A0A087X501_POEFO Loading...

Gastrin/cholecystokinin type B receptor

Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

AlphaFold DB , UniProt , Accession A0A087X501, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 456 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	29	Very low	28.1	Very low	241 Å²	241	127.9 Å²	127.9	100%	1.187	71%	0.711	S	S	*	*				0	22.8	0	-106.3	173.8	-81.3	0	0	113.1
2	E	29.8	Very low	28	Very low	189 Å²	189	128.3 Å²	128.3	88%	0.883	70%	0.703	S	S	*	*			trans	-118.6	14.6	178.2	-79.3	173.2	129.6	0	0	113.8
3	A	27.8	Very low	28	Very low	89 Å²	89	130.4 Å²	130.4	74%	0.736	71%	0.712	S	S	*	*	S	Bend	trans	-92	-2.2	173.7	0	0	0	0	0	113.6
4	H	24.9	Very low	27.8	Very low	159 Å²	159	131.9 Å²	131.9	74%	0.736	72%	0.717	S	S	*	*	S	Bend	trans	-104.9	-7.6	-174.6	-93.1	-75.3	0	0	0	115.1
5	A	27.3	Very low	27.6	Very low	76 Å²	76	128.9 Å²	128.9	63%	0.628	71%	0.71	S	S	*	*	S	Bend	trans	-89.8	-29.5	-178.3	0	0	0	0	0	113.6
6	A	28.6	Very low	27.8	Very low	85 Å²	85	128.4 Å²	128.4	70%	0.702	71%	0.712	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.4	-16.2	-179.6	0	0	0	0	0	113.9	R8	A6-R8 VanDerWaalsContact C-N 3.34Å
7	N	28	Very low	27.8	Very low	98 Å²	98	126.9 Å²	126.9	52%	0.524	71%	0.711	S	S	.	*	T	Hydrogen-bonded Turn	trans	-87.8	-2.6	-179.1	-147.4	8.1	0	0	0	113.2	K11	N7-K11 WeakPolarHBondContact O-CG 3.39Å
8	R	27.8	Very low	27.6	Very low	178 Å²	178	132.8 Å²	132.8	67%	0.672	72%	0.72	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.7	-37	-179.8	-146.6	176.9	-76.2	-154.7	-1	111.8	A6 A10 K11 E12	A6-R8 VanDerWaalsContact C-N 3.34Å; R8-A10 PolarHBondContact O-N 3.28Å; R8-K11 PolarHBondContact O-N 3.49Å; R8-E12 PolarHBondContact O-N 3.31Å
9	S	30.2	Very low	27.4	Very low	88 Å²	88	135.8 Å²	135.8	62%	0.615	73%	0.729	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.5	-19.1	-179.6	-57.3	0	0	0	0	115.2
10	A	28.3	Very low	27.5	Very low	63 Å²	63	134.7 Å²	134.7	52%	0.521	73%	0.73	S	S	.	*	T	Hydrogen-bonded Turn	trans	-87.4	-20.9	170.7	0	0	0	0	0	112.9	R8	R8-A10 PolarHBondContact O-N 3.28Å
11	K	28	Very low	27.5	Very low	141 Å²	141	131.9 Å²	131.9	61%	0.613	73%	0.732	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.4	-27.6	176.8	-81	-175	175	-172.7	0	113	N7 R8 S15	N7-K11 WeakPolarHBondContact O-CG 3.39Å; R8-K11 PolarHBondContact O-N 3.49Å; K11-S15 WeakPolarHBondContact O-CB 3.46Å; K11-S15 PolarHBondContact O-N 3.11Å; K11-S15 PolarHBondContact O-OG 2.94Å
12	E	26.7	Very low	27.2	Very low	132 Å²	132	128.3 Å²	128.3	62%	0.617	72%	0.717	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.4	-14.9	-178.9	-79.3	-176.6	155.7	0	0	115.3	R8	R8-E12 PolarHBondContact O-N 3.31Å
13	L	27.9	Very low	27.1	Very low	156 Å²	156	125.7 Å²	125.7	82%	0.817	71%	0.714	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.8	-3.3	175.7	-74.4	171.6	0	0	0	114
14	L	25.5	Very low	26.9	Very low	151 Å²	151	126.9 Å²	126.9	79%	0.791	72%	0.717	S	S	*	*	T	Hydrogen-bonded Turn	trans	-120.2	-0.7	178.1	-78.3	166.2	0	0	0	113.7
15	S	23.9	Very low	27.6	Very low	88 Å²	88	126.1 Å²	126.1	62%	0.615	72%	0.723	S	S	*	*	S	Bend	trans	-91.2	10.8	-178.8	68.2	0	0	0	0	115.4	K11	K11-S15 WeakPolarHBondContact O-CB 3.46Å; K11-S15 PolarHBondContact O-N 3.11Å; K11-S15 PolarHBondContact O-OG 2.94Å
16	V	30.8	Very low	27.6	Very low	121 Å²	121	125.9 Å²	125.9	73%	0.733	73%	0.729	S	S	*	*	S	Bend	trans	-97.7	-5.6	-173.3	178.8	0	0	0	0	114.3
17	C	27.8	Very low	27.6	Very low	103 Å²	103	129.2 Å²	129.2	70%	0.696	74%	0.735	S	S	*	*	S	Bend	trans	-148.1	40	-176.1	-83.9	0	0	0	0	115.9
18	W	25.2	Very low	27.6	Very low	233 Å²	233	131.3 Å²	131.3	88%	0.883	75%	0.751	S	S	*	*			trans	-151.2	84.4	168.8	-155	-87.1	0	0	0	113.9
19	E	24.1	Very low	28	Very low	190 Å²	190	128 Å²	128	89%	0.888	76%	0.755	S	S	*	*			trans	-129.4	125.2	150.1	-83.2	-168.1	140.5	0	0	108.8	G21	E19-G21 PolarHBondContact O-N 3.42Å
20	P	28.5	Very low	27.9	Very low	113 Å²	113	130.2 Å²	130.2	73%	0.734	77%	0.765	S	S	*	*			trans	-76.6	118.9	169.2	29.7	-27.1	0	0	0	108.5	N22	P20-N22 PolarHBondContact O-N 2.89Å
21	G	27.1	Very low	27.9	Very low	75 Å²	75	134.6 Å²	134.6	77%	0.773	78%	0.779	S	S	*	*			trans	-61.2	125.1	-179.6	0	0	0	0	0	112.5	E19	E19-G21 PolarHBondContact O-N 3.42Å
22	N	23.8	Very low	28	Very low	166 Å²	166	135.9 Å²	135.9	89%	0.888	79%	0.792	S	S	*	*			trans	-94	105.4	160.3	-121.6	3.2	0	0	0	107.4	P20 S24	P20-N22 PolarHBondContact O-N 2.89Å; N22-S24 PolarHBondContact O-N 2.99Å
23	V	26.3	Very low	28.2	Very low	134 Å²	134	138.6 Å²	138.6	81%	0.812	81%	0.807	S	S	*	*			trans	-74.1	114.9	176.3	175.8	0	0	0	0	108.5
24	S	25.2	Very low	28.5	Very low	115 Å²	115	138 Å²	138	80%	0.804	81%	0.805	S	S	*	*			trans	-108.4	125.6	162.5	47.3	0	0	0	0	108.5	N22	N22-S24 PolarHBondContact O-N 2.99Å
25	V	38.9	Very low	28.8	Very low	142 Å²	142	139.2 Å²	139.2	86%	0.861	81%	0.806	S	S	*	*			trans	-79.6	124.9	-179.9	174.6	0	0	0	0	108.7
26	G	26.3	Very low	29.1	Very low	72 Å²	72	141.6 Å²	141.6	74%	0.742	81%	0.812	S	S	*	*			trans	-162.2	114.2	172.6	0	0	0	0	0	112
27	N	29.7	Very low	29.5	Very low	155 Å²	155	141.3 Å²	141.3	83%	0.829	81%	0.811	S	S	*	*			trans	-49.9	133.5	-179.6	-79.9	-19.4	0	0	0	114.5
28	T	28.1	Very low	29.9	Very low	142 Å²	142	141.5 Å²	141.5	87%	0.871	81%	0.809	S	S	*	*				-179.4	140.5	114.2	23.5	0	0	0	0	111.3
29	S	35.8	Very low	31	Very low	109 Å²	109	135.3 Å²	135.3	76%	0.762	80%	0.8	S	S	*	*			trans	-69.9	128	-177	46.4	0	0	0	0	114.3
30	V	28.5	Very low	32	Very low	134 Å²	134	129.4 Å²	129.4	81%	0.812	78%	0.78	S	S	*	*			trans	-158	121.2	141.7	-177.3	0	0	0	0	109.9
31	D	27.6	Very low	33.3	Very low	154 Å²	154	130.7 Å²	130.7	82%	0.824	78%	0.781	S	S	*	*			trans	29	122.2	158.4	-61.2	-37.9	0	0	0	123.4	M33	D31-M33 PolarHBondContact O-N 3.5Å
32	L	31.1	Very low	34.4	Very low	168 Å²	168	130.5 Å²	130.5	88%	0.88	77%	0.767	S	S	*	*			trans	-64.1	115.5	163	-75.1	147	0	0	0	111.5
33	M	29.3	Very low	36	Very low	190 Å²	190	126 Å²	126	94%	0.936	75%	0.749	S	S	*	*			trans	-126.5	117.3	142.8	-91.7	-164.6	159.9	0	0	108.8	D31 Q35	D31-M33 PolarHBondContact O-N 3.5Å; M33-Q35 PolarHBondContact O-N 3.25Å
34	D	34.3	Very low	37.7	Very low	143 Å²	143	124.4 Å²	124.4	77%	0.765	74%	0.739	S	S	*	*			trans	-53.3	111.5	177.7	-79.2	-51.5	0	0	0	112.6
35	Q	32	Very low	39.6	Very low	177 Å²	177	124.3 Å²	124.3	83%	0.827	73%	0.729	S	S	*	*			trans	-119.7	82.6	147.3	-84.3	-173.2	6.3	0	0	109.2	M33 T37	M33-Q35 PolarHBondContact O-N 3.25Å; Q35-T37 PolarHBondContact O-N 3.27Å
36	N	30.7	Very low	40.8	Very low	138 Å²	138	122.3 Å²	122.3	74%	0.738	71%	0.713	S	S	*	*			trans	-69.3	71.1	170.1	-145	0.3	0	0	0	109.5	T38	N36-T38 VanDerWaalsContact C-N 3.27Å; N36-T38 PolarHBondContact O-N 3.39Å
37	T	39.2	Very low	42.5	Very low	115 Å²	115	128.5 Å²	128.5	71%	0.706	71%	0.714	S	S	*	*			trans	-82.3	78.5	176.6	-39.9	0	0	0	0	108.8	Q35 C39	Q35-T37 PolarHBondContact O-N 3.27Å; T37-C39 PolarHBondContact O-N 3.39Å; T37-C39 VanDerWaalsContact O-N 3.16Å
38	T	36.6	Very low	44.1	Very low	106 Å²	106	123.7 Å²	123.7	65%	0.65	70%	0.696	S	S	*	*			trans	-69.8	103.7	169.4	30.7	0	0	0	0	108.9	N36 S40	N36-T38 VanDerWaalsContact C-N 3.27Å; N36-T38 PolarHBondContact O-N 3.39Å; T38-S40 PolarHBondContact O-N 3.24Å
39	C	48	Very low	46.1	Very low	104 Å²	104	119.8 Å²	119.8	70%	0.703	67%	0.672	S	S	*	*			trans	-53.3	111.8	163.8	-77	0	0	0	0	108.4	T37 N41	T37-C39 PolarHBondContact O-N 3.39Å; T37-C39 VanDerWaalsContact O-N 3.16Å; C39-N41 PolarHBondContact O-N 3.16Å
40	S	45.7	Very low	47.7	Very low	66 Å²	66	122.9 Å²	122.9	46%	0.462	67%	0.667	S	S	.	*			trans	-71	105.2	-166.1	-29.6	0	0	0	0	110.3	T38 S42 S43	T38-S40 PolarHBondContact O-N 3.24Å; S40-S42 WeakPolarHBondContact CB-OG 3.46Å; S40-S42 PolarHBondContact O-N 2.85Å; S40-S43 PolarHBondContact O-N 2.88Å; S40-S43 PolarHBondContact O-OG 3.45Å
41	N	54.1	Low	49.5	Very low	140 Å²	140	118.9 Å²	118.9	75%	0.749	65%	0.648	S	S	*	*	H	α-helix	trans	-51.8	-26.6	172.4	-79.2	-21.4	0	0	0	112.9	C39 L45	C39-N41 PolarHBondContact O-N 3.16Å; N41-L45 VanDerWaalsContact O-CB 3.27Å; N41-L45 WeakPolarHBondContact O-CB 3.49Å; N41-L45 PolarHBondContact O-N 3.4Å
42	S	51.7	Low	51.7	Low	71 Å²	71	120.8 Å²	120.8	50%	0.497	64%	0.644	S	S	.	*	H	α-helix	trans	-63.9	-35	174.7	47.7	0	0	0	0	113.6	S40 N46	S40-S42 WeakPolarHBondContact CB-OG 3.46Å; S40-S42 PolarHBondContact O-N 2.85Å; S42-N46 WeakPolarHBondContact O-CB 3.24Å; S42-N46 PolarHBondContact O-N 2.93Å; S42-N46 PolarHBondContact O-ND2 3.41Å; S42-N46 VanDerWaalsContact O-ND2 3.1Å
43	S	57.6	Low	54	Low	71 Å²	71	118.8 Å²	118.8	50%	0.497	63%	0.63	S	S	.	*	H	α-helix	trans	-73.4	-38.2	179.8	70.2	0	0	0	0	112.5	S40 R47	S40-S43 PolarHBondContact O-N 2.88Å; S40-S43 PolarHBondContact O-OG 3.45Å; S43-R47 WeakPolarHBondContact O-CB 3.3Å; S43-R47 PolarHBondContact O-N 3.34Å
44	V	61.8	Low	56.2	Low	100 Å²	100	113 Å²	113	61%	0.606	60%	0.601	S	S	*	*	H	α-helix	trans	-72.2	-44.7	177.4	180	0	0	0	0	110.4	R47 A48	V44-R47 PolarHBondContact O-N 2.64Å; V44-A48 WeakPolarHBondContact O-CB 3.19Å; V44-A48 PolarHBondContact O-N 3.5Å
45	L	65.1	Low	58.4	Low	113 Å²	113	108.9 Å²	108.9	59%	0.592	58%	0.579	S	S	*	*	H	α-helix	trans	-61	-46	174.1	-172.7	66.4	0	0	0	110.9	N41 R47 A48 T49	N41-L45 VanDerWaalsContact O-CB 3.27Å; N41-L45 WeakPolarHBondContact O-CB 3.49Å; N41-L45 PolarHBondContact O-N 3.4Å; L45-R47 VanDerWaalsContact C-N 3.31Å; L45-R47 PolarHBondContact O-N 3.03Å; L45-A48 PolarHBondContact O-N 3.15Å; L45-T49 WeakPolarHBondContact O-CB 3.47Å; L45-T49 PolarHBondContact O-N 3.35Å; L45-T49 PolarHBondContact O-OG1 3.43Å
46	N	63.4	Low	60.9	Low	100 Å²	100	104 Å²	104	54%	0.535	57%	0.565	S	S	.	*	H	α-helix	trans	-62.7	-35.6	176.7	-78.1	-23.9	0	0	0	112.9	S42 R50	S42-N46 WeakPolarHBondContact O-CB 3.24Å; S42-N46 PolarHBondContact O-N 2.93Å; S42-N46 PolarHBondContact O-ND2 3.41Å; S42-N46 VanDerWaalsContact O-ND2 3.1Å; N46-R50 WeakPolarHBondContact O-CB 3.42Å; N46-R50 PolarHBondContact O-N 3.5Å
47	R	62.8	Low	63.5	Low	203 Å²	203	102.6 Å²	102.6	77%	0.766	55%	0.552	S	S	*	*	H	α-helix	trans	-69.9	-40.8	175.7	-170.4	177.5	-76	-158	-1.8	111.7	S43 V44 L45 A51	S43-R47 WeakPolarHBondContact O-CB 3.3Å; S43-R47 PolarHBondContact O-N 3.34Å; V44-R47 PolarHBondContact O-N 2.64Å; L45-R47 VanDerWaalsContact C-N 3.31Å; L45-R47 PolarHBondContact O-N 3.03Å; R47-A51 WeakPolarHBondContact O-CB 3.45Å; R47-A51 PolarHBondContact O-N 2.95Å
48	A	63.1	Low	65.6	Low	54 Å²	54	99.1 Å²	99.1	45%	0.446	53%	0.526	S	S	.	.	H	α-helix	trans	-67.8	-42.3	176.4	0	0	0	0	0	112.4	V44 L45 A51 R52	V44-A48 WeakPolarHBondContact O-CB 3.19Å; V44-A48 PolarHBondContact O-N 3.5Å; L45-A48 PolarHBondContact O-N 3.15Å; A48-A51 PolarHBondContact O-N 3.33Å; A48-R52 PolarHBondContact O-N 3Å
49	T	69.4	Low	68	Low	60 Å²	60	97.2 Å²	97.2	37%	0.368	51%	0.512	S	S	.	.	H	α-helix	trans	-63.9	-47.4	175.6	-53.1	0	0	0	0	110.7	L45 A51 R52 E53	L45-T49 WeakPolarHBondContact O-CB 3.47Å; L45-T49 PolarHBondContact O-N 3.35Å; L45-T49 PolarHBondContact O-OG1 3.43Å; T49-A51 VanDerWaalsContact C-N 3.31Å; T49-A51 PolarHBondContact O-N 3.44Å; T49-R52 PolarHBondContact O-N 2.8Å; T49-E53 WeakPolarHBondContact O-CG 3.48Å; T49-E53 PolarHBondContact O-N 3.01Å
50	R	68.8	Low	70	Confident	174 Å²	174	97.4 Å²	97.4	66%	0.657	51%	0.505	S	S	*	.	H	α-helix	trans	-61.2	-38.7	176.8	-169	-177.1	-65.1	-178.5	-0.9	112.1	N46 E53 M54	N46-R50 WeakPolarHBondContact O-CB 3.42Å; N46-R50 PolarHBondContact O-N 3.5Å; R50-E53 PolarHBondContact O-N 2.76Å; R50-M54 HydrophobicContact CG-CG 4.5Å; R50-M54 WeakPolarHBondContact O-CB 3.21Å; R50-M54 WeakPolarHBondContact O-CG 3.32Å; R50-M54 PolarHBondContact O-N 2.96Å
51	A	68.1	Low	72.2	Confident	49 Å²	49	96.2 Å²	96.2	41%	0.405	49%	0.493	S	S	.	.	H	α-helix	trans	-62.4	-46.8	175	0	0	0	0	0	111.8	R47 A48 T49 E53 M54 D55	R47-A51 WeakPolarHBondContact O-CB 3.45Å; R47-A51 PolarHBondContact O-N 2.95Å; A48-A51 PolarHBondContact O-N 3.33Å; T49-A51 VanDerWaalsContact C-N 3.31Å; T49-A51 PolarHBondContact O-N 3.44Å; A51-E53 PolarHBondContact O-N 3.06Å; A51-M54 PolarHBondContact O-N 2.94Å; A51-D55 PolarHBondContact O-N 2.98Å
52	R	73.6	Confident	73.8	Confident	195 Å²	195	89.9 Å²	89.9	74%	0.736	46%	0.459	S	S	*	.	H	α-helix	trans	-64.7	-37.3	177	-75.7	-167.9	176.5	-177.1	1.2	113.6	A48 T49 S56	A48-R52 PolarHBondContact O-N 3Å; T49-R52 PolarHBondContact O-N 2.8Å; R52-S56 WeakPolarHBondContact O-CB 3.39Å; R52-S56 PolarHBondContact O-N 2.96Å; R52-S56 PolarHBondContact O-OG 2.96Å
53	E	78.9	Confident	75.7	Confident	126 Å²	126	89 Å²	89	59%	0.589	45%	0.452	S	S	*	.	H	α-helix	trans	-64.8	-44.3	175	-74.9	179.9	160.7	0	0	111.2	T49 R50 A51 D55 S56 F57	T49-E53 WeakPolarHBondContact O-CG 3.48Å; T49-E53 PolarHBondContact O-N 3.01Å; R50-E53 PolarHBondContact O-N 2.76Å; A51-E53 PolarHBondContact O-N 3.06Å; E53-D55 PolarHBondContact O-N 2.77Å; E53-S56 PolarHBondContact O-N 3.35Å; E53-F57 WeakPolarHBondContact O-CB 3.41Å; E53-F57 PolarHBondContact O-N 3.29Å
54	M	75.9	Confident	77.4	Confident	67 Å²	67	89.8 Å²	89.8	33%	0.33	45%	0.451	S	S	.	.	H	α-helix	trans	-64.3	-39.6	177.8	-68.7	-65.3	-73.2	0	0	111.9	R50 A51 R58 A370 F374	R50-M54 HydrophobicContact CG-CG 4.5Å; R50-M54 WeakPolarHBondContact O-CB 3.21Å; R50-M54 WeakPolarHBondContact O-CG 3.32Å; R50-M54 PolarHBondContact O-N 2.96Å; A51-M54 PolarHBondContact O-N 2.94Å; M54-R58 WeakPolarHBondContact O-CB 3.28Å; M54-R58 WeakPolarHBondContact O-CD 3.3Å; M54-R58 WeakPolarHBondContact O-CG 3.35Å; M54-R58 PolarHBondContact O-N 2.66Å; M54-A370 HydrophobicContact CE-CB 4.44Å; M54-F374 HydrophobicContact CE-CE2 3.61Å; M54-F374 HydrophobicContact CE-CZ 3.76Å
55	D	78.9	Confident	78.9	Confident	58 Å²	58	85.6 Å²	85.6	31%	0.31	43%	0.425	S	S	.	.	H	α-helix	trans	-68.5	-40.8	175.3	-69.5	-26.6	0	0	0	111.9	A51 E53 F57 R58 I59	A51-D55 PolarHBondContact O-N 2.98Å; E53-D55 PolarHBondContact O-N 2.77Å; D55-F57 PolarHBondContact O-N 3.26Å; D55-R58 PolarHBondContact O-N 3.45Å; D55-R58 IonicContact OD1-CZ 2.76Å; D55-R58 IonicContact OD1-NH1 2.71Å; D55-R58 PolarHBondContact OD1-NH1 3.34Å; D55-I59 WeakPolarHBondContact O-CD1 3.35Å; D55-I59 VanDerWaalsContact O-CG1 3.24Å; D55-I59 WeakPolarHBondContact O-CG1 3.48Å; D55-I59 PolarHBondContact O-N 3.01Å
56	S	84.9	Confident	80.2	Confident	75 Å²	75	83.5 Å²	83.5	52%	0.524	41%	0.411	S	S	.	.	H	α-helix	trans	-61.5	-44.5	175.8	-58.6	0	0	0	0	111.7	R52 E53 I59 L60	R52-S56 WeakPolarHBondContact O-CB 3.39Å; R52-S56 PolarHBondContact O-N 2.96Å; R52-S56 PolarHBondContact O-OG 2.96Å; E53-S56 PolarHBondContact O-N 3.35Å; S56-I59 PolarHBondContact O-N 3.3Å; S56-L60 PolarHBondContact O-N 3.16Å
57	F	86.1	Confident	81.7	Confident	108 Å²	108	82.8 Å²	82.8	47%	0.474	41%	0.407	S	S	.	.	H	α-helix	trans	-63.1	-42.9	175.5	-177.9	-112.5	0	0	0	112.2	E53 D55 L60 L61 F374	E53-F57 WeakPolarHBondContact O-CB 3.41Å; E53-F57 PolarHBondContact O-N 3.29Å; D55-F57 PolarHBondContact O-N 3.26Å; F57-L60 PolarHBondContact O-N 2.98Å; F57-L61 HydrophobicContact CD1-CD1 3.89Å; F57-L61 HydrophobicContact CE1-CD1 3.36Å; F57-L61 HydrophobicContact CE1-CG 4.27Å; F57-L61 HydrophobicContact CE2-CD1 4.21Å; F57-L61 HydrophobicContact CE2-CG 4.33Å; F57-L61 HydrophobicContact CZ-CD1 3.55Å; F57-L61 HydrophobicContact CZ-CD2 4.42Å; F57-L61 HydrophobicContact CZ-CG 4.15Å; F57-L61 WeakPolarHBondContact O-CG 3.48Å; F57-L61 PolarHBondContact O-N 2.92Å; F57-F374 HydrophobicContact CD1-CE1 4.14Å; F57-F374 HydrophobicContact CD1-CZ 4.26Å; F57-F374 HydrophobicContact CE1-CE1 4.11Å
58	R	83.3	Confident	83.2	Confident	41 Å²	41	76.7 Å²	76.7	16%	0.155	39%	0.389	C	S	.	.	H	α-helix	trans	-60.5	-46.9	174.9	-72.8	165.5	-165.2	166.9	7.7	111.8	M54 D55 L60 L61 Y62 F374	M54-R58 WeakPolarHBondContact O-CB 3.28Å; M54-R58 WeakPolarHBondContact O-CD 3.3Å; M54-R58 WeakPolarHBondContact O-CG 3.35Å; M54-R58 PolarHBondContact O-N 2.66Å; D55-R58 PolarHBondContact O-N 3.45Å; D55-R58 IonicContact OD1-CZ 2.76Å; D55-R58 IonicContact OD1-NH1 2.71Å; D55-R58 PolarHBondContact OD1-NH1 3.34Å; R58-L60 VanDerWaalsContact C-N 3.29Å; R58-L60 PolarHBondContact O-N 3.07Å; R58-L61 PolarHBondContact O-N 2.99Å; R58-Y62 WeakPolarHBondContact O-CB 3.4Å; R58-Y62 WeakPolarHBondContact O-CD2 3.36Å; R58-Y62 PolarHBondContact O-N 3.33Å; R58-F374 HydrophobicContact CG-CE1 4.21Å; R58-F374 HydrophobicContact CG-CZ 4.06Å
59	I	87.4	Confident	84.7	Confident	67 Å²	67	74.1 Å²	74.1	34%	0.344	37%	0.368	S	S	.	.	H	α-helix	trans	-58.9	-44.2	178.9	-70	162.3	0	0	0	110.3	D55 S56 Y62 S63 I117	D55-I59 WeakPolarHBondContact O-CD1 3.35Å; D55-I59 VanDerWaalsContact O-CG1 3.24Å; D55-I59 WeakPolarHBondContact O-CG1 3.48Å; D55-I59 PolarHBondContact O-N 3.01Å; S56-I59 PolarHBondContact O-N 3.3Å; I59-Y62 PolarHBondContact O-N 3.22Å; I59-S63 VanDerWaalsContact O-CB 3.25Å; I59-S63 WeakPolarHBondContact O-CB 3.19Å; I59-S63 PolarHBondContact O-N 3.33Å; I59-S63 PolarHBondContact O-OG 3.46Å; I59-I117 HydrophobicContact CD1-CD1 3.94Å; I59-I117 HydrophobicContact CG1-CD1 3.59Å; I59-I117 HydrophobicContact CG1-CG1 4.44Å
60	L	90.3	Very high	85.9	Confident	107 Å²	107	72.7 Å²	72.7	56%	0.56	36%	0.359	S	S	*	.	H	α-helix	trans	-60.7	-47.1	177.7	-175.9	145.8	0	0	0	111.4	S56 F57 R58 S63 L64	S56-L60 PolarHBondContact O-N 3.16Å; F57-L60 PolarHBondContact O-N 2.98Å; R58-L60 VanDerWaalsContact C-N 3.29Å; R58-L60 PolarHBondContact O-N 3.07Å; L60-S63 PolarHBondContact O-N 3.43Å; L60-L64 WeakPolarHBondContact O-CB 3.31Å; L60-L64 PolarHBondContact O-N 3.23Å
61	L	90.1	Very high	87.1	Confident	41 Å²	41	71 Å²	71	22%	0.215	36%	0.356	C	S	.	.	H	α-helix	trans	-65.9	-44.8	178.9	-70.4	179	0	0	0	112.7	F57 R58 S63 L64 I65 F374 L377	F57-L61 HydrophobicContact CD1-CD1 3.89Å; F57-L61 HydrophobicContact CE1-CD1 3.36Å; F57-L61 HydrophobicContact CE1-CG 4.27Å; F57-L61 HydrophobicContact CE2-CD1 4.21Å; F57-L61 HydrophobicContact CE2-CG 4.33Å; F57-L61 HydrophobicContact CZ-CD1 3.55Å; F57-L61 HydrophobicContact CZ-CD2 4.42Å; F57-L61 HydrophobicContact CZ-CG 4.15Å; F57-L61 WeakPolarHBondContact O-CG 3.48Å; F57-L61 PolarHBondContact O-N 2.92Å; R58-L61 PolarHBondContact O-N 2.99Å; L61-S63 VanDerWaalsContact C-N 3.32Å; L61-S63 PolarHBondContact O-N 2.83Å; L61-L64 PolarHBondContact O-N 3.28Å; L61-I65 WeakPolarHBondContact O-CG1 3.27Å; L61-I65 PolarHBondContact O-N 3.28Å; L61-F374 HydrophobicContact CD1-CE1 4.49Å; L61-L377 HydrophobicContact CB-CD1 4.07Å; L61-L377 HydrophobicContact CB-CD2 3.78Å; L61-L377 HydrophobicContact CD1-CD2 3.58Å; L61-L377 HydrophobicContact CG-CD2 4.32Å
62	Y	89	Confident	88.2	Confident	8 Å²	8	69.4 Å²	69.4	3%	0.031	35%	0.345	C	S	.	.	H	α-helix	trans	-60.2	-44.3	175.8	-97.2	-87	0	0	0	111.4	R58 I59 L64 I65 F66 L113 L377 Y380	R58-Y62 WeakPolarHBondContact O-CB 3.4Å; R58-Y62 WeakPolarHBondContact O-CD2 3.36Å; R58-Y62 PolarHBondContact O-N 3.33Å; I59-Y62 PolarHBondContact O-N 3.22Å; Y62-L64 PolarHBondContact O-N 3.45Å; Y62-I65 PolarHBondContact O-N 2.9Å; Y62-F66 WeakPolarHBondContact O-CB 3.32Å; Y62-F66 PolarHBondContact O-N 2.84Å; Y62-L113 HydrophobicContact CD1-CB 4.25Å; Y62-L113 HydrophobicContact CD1-CD1 4.11Å; Y62-L113 HydrophobicContact CD1-CD2 4.39Å; Y62-L113 HydrophobicContact CD1-CG 4.48Å; Y62-L113 HydrophobicContact CD2-CD1 3.67Å; Y62-L113 HydrophobicContact CE2-CD1 4.15Å; Y62-L113 HydrophobicContact CG-CD1 3.67Å; Y62-L113 HydrophobicContact CG-CD2 4.16Å; Y62-L113 HydrophobicContact CG-CG 4.36Å; Y62-L377 HydrophobicContact CD1-CD1 4.28Å; Y62-L377 HydrophobicContact CD2-CD1 3.46Å; Y62-L377 VanDerWaalsContact CD2-CD1 3.46Å; Y62-L377 HydrophobicContact CE1-CD1 4.42Å; Y62-L377 HydrophobicContact CE2-CB 4.19Å; Y62-L377 HydrophobicContact CE2-CD1 3.6Å; Y62-L377 HydrophobicContact CE2-CG 4.49Å; Y62-L377 HydrophobicContact CG-CD1 3.81Å; Y62-Y380 AromaticContact CE1-CD2 3.59Å; Y62-Y380 HydrophobicContact CE1-CD2 3.59Å; Y62-Y380 AromaticContact CE1-CE2 3.66Å; Y62-Y380 HydrophobicContact CE1-CE2 3.66Å
63	S	90.9	Very high	89.2	Confident	52 Å²	52	60.2 Å²	60.2	36%	0.364	31%	0.31	S	S	.	.	H	α-helix	trans	-62.8	-43.4	178.1	-58.8	0	0	0	0	111.1	I59 L60 L61 F66 L67	I59-S63 VanDerWaalsContact O-CB 3.25Å; I59-S63 WeakPolarHBondContact O-CB 3.19Å; I59-S63 PolarHBondContact O-N 3.33Å; I59-S63 PolarHBondContact O-OG 3.46Å; L60-S63 PolarHBondContact O-N 3.43Å; L61-S63 VanDerWaalsContact C-N 3.32Å; L61-S63 PolarHBondContact O-N 2.83Å; S63-F66 PolarHBondContact O-N 2.92Å; S63-L67 WeakPolarHBondContact O-CB 3.49Å; S63-L67 WeakPolarHBondContact O-CG 3.33Å; S63-L67 PolarHBondContact O-N 3.01Å
64	L	92.7	Very high	90	Very high	87 Å²	87	58.1 Å²	58.1	46%	0.455	30%	0.303	S	S	.	.	H	α-helix	trans	-61.6	-49.5	176.5	180	63.9	0	0	0	111.7	L60 L61 Y62 F66 L67 L68	L60-L64 WeakPolarHBondContact O-CB 3.31Å; L60-L64 PolarHBondContact O-N 3.23Å; L61-L64 PolarHBondContact O-N 3.28Å; Y62-L64 PolarHBondContact O-N 3.45Å; L64-F66 VanDerWaalsContact C-N 3.34Å; L64-F66 PolarHBondContact O-N 2.9Å; L64-L67 PolarHBondContact O-N 3.25Å; L64-L68 HydrophobicContact CD1-CD1 3.93Å; L64-L68 HydrophobicContact CD1-CG 4.15Å; L64-L68 HydrophobicContact CG-CD1 3.91Å; L64-L68 HydrophobicContact CG-CG 4.48Å; L64-L68 WeakPolarHBondContact O-CB 3.29Å; L64-L68 VanDerWaalsContact O-CG 3.25Å; L64-L68 WeakPolarHBondContact O-CG 3.3Å; L64-L68 PolarHBondContact O-N 3.17Å
65	I	93.4	Very high	90.7	Very high	13 Å²	13	57.2 Å²	57.2	7%	0.067	30%	0.299	C	S	.	.	H	α-helix	trans	-62.2	-43.7	178.9	-69	175.8	0	0	0	110.8	L61 Y62 L68 S69 M109 L377 T381 C384	L61-I65 WeakPolarHBondContact O-CG1 3.27Å; L61-I65 PolarHBondContact O-N 3.28Å; Y62-I65 PolarHBondContact O-N 2.9Å; I65-L68 PolarHBondContact O-N 3.03Å; I65-S69 WeakPolarHBondContact O-CB 3.32Å; I65-S69 PolarHBondContact O-N 2.93Å; I65-M109 HydrophobicContact CG2-CE 4.08Å; I65-M109 HydrophobicContact CG2-SD 4.12Å; I65-L377 HydrophobicContact CD1-CD1 3.48Å; I65-L377 VanDerWaalsContact CD1-CD1 3.48Å; I65-L377 HydrophobicContact CD1-CG 3.73Å; I65-T381 WeakPolarHBondContact CD1-OG1 3.39Å; I65-C384 HydrophobicContact CG2-CB 4.36Å
66	F	93.8	Very high	91.3	Very high	68 Å²	68	54.7 Å²	54.7	30%	0.298	29%	0.286	S	S	.	.	H	α-helix	trans	-58.5	-52.1	177.6	172.7	-98.4	0	0	0	111.2	Y62 S63 L64 L68 S69 V70 A105 M109 P110	Y62-F66 WeakPolarHBondContact O-CB 3.32Å; Y62-F66 PolarHBondContact O-N 2.84Å; S63-F66 PolarHBondContact O-N 2.92Å; L64-F66 VanDerWaalsContact C-N 3.34Å; L64-F66 PolarHBondContact O-N 2.9Å; F66-L68 PolarHBondContact O-N 3.16Å; F66-S69 PolarHBondContact O-N 3.45Å; F66-V70 HydrophobicContact CD2-CG2 4.16Å; F66-V70 HydrophobicContact CE1-CG2 4.29Å; F66-V70 HydrophobicContact CE2-CG2 3.81Å; F66-V70 HydrophobicContact CZ-CG2 3.89Å; F66-V70 WeakPolarHBondContact O-CG2 3.27Å; F66-V70 PolarHBondContact O-N 2.95Å; F66-A105 WeakPolarHBondContact CD2-O 3.39Å; F66-A105 VanDerWaalsContact CE2-O 3.27Å; F66-A105 WeakPolarHBondContact CE2-O 3.01Å; F66-M109 HydrophobicContact CB-SD 4.32Å; F66-M109 HydrophobicContact CD2-CB 4.4Å; F66-M109 HydrophobicContact CD2-SD 4.47Å; F66-P110 HydrophobicContact CD2-CG 4.4Å; F66-P110 HydrophobicContact CE2-CG 3.99Å
67	L	93.8	Very high	91.6	Very high	86 Å²	86	52.8 Å²	52.8	45%	0.45	27%	0.269	S	S	.	.	H	α-helix	trans	-61.9	-48.2	179.8	-66.6	169.4	0	0	0	110.9	S63 L64 S69 V70 F71	S63-L67 WeakPolarHBondContact O-CB 3.49Å; S63-L67 WeakPolarHBondContact O-CG 3.33Å; S63-L67 PolarHBondContact O-N 3.01Å; L64-L67 PolarHBondContact O-N 3.25Å; L67-S69 VanDerWaalsContact C-N 3.3Å; L67-S69 PolarHBondContact O-N 3Å; L67-V70 PolarHBondContact O-N 3.36Å; L67-F71 HydrophobicContact CB-CD2 4.16Å; L67-F71 HydrophobicContact CB-CE2 4.26Å; L67-F71 HydrophobicContact CD2-CD2 4.46Å; L67-F71 HydrophobicContact CD2-CE2 3.77Å; L67-F71 WeakPolarHBondContact O-CB 3.34Å; L67-F71 WeakPolarHBondContact O-CD2 3.26Å; L67-F71 PolarHBondContact O-N 3.45Å
68	L	93.6	Very high	91.8	Very high	75 Å²	75	50.4 Å²	50.4	39%	0.393	26%	0.263	S	S	.	.	H	α-helix	trans	-59.9	-41.4	178.3	-71.9	174.7	0	0	0	112	L64 I65 F66 G72 C384	L64-L68 HydrophobicContact CD1-CD1 3.93Å; L64-L68 HydrophobicContact CD1-CG 4.15Å; L64-L68 HydrophobicContact CG-CD1 3.91Å; L64-L68 HydrophobicContact CG-CG 4.48Å; L64-L68 WeakPolarHBondContact O-CB 3.29Å; L64-L68 VanDerWaalsContact O-CG 3.25Å; L64-L68 WeakPolarHBondContact O-CG 3.3Å; L64-L68 PolarHBondContact O-N 3.17Å; I65-L68 PolarHBondContact O-N 3.03Å; F66-L68 PolarHBondContact O-N 3.16Å; L68-G72 WeakPolarHBondContact O-CA 3.43Å; L68-G72 PolarHBondContact O-N 3.46Å; L68-C384 HydrophobicContact CB-CB 3.85Å
69	S	94.6	Very high	91.9	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-66.8	-49.8	178.7	-171.9	0	0	0	0	111.6	I65 F66 L67 N73	I65-S69 WeakPolarHBondContact O-CB 3.32Å; I65-S69 PolarHBondContact O-N 2.93Å; F66-S69 PolarHBondContact O-N 3.45Å; L67-S69 VanDerWaalsContact C-N 3.3Å; L67-S69 PolarHBondContact O-N 3Å; S69-N73 VanDerWaalsContact O-CB 3.25Å; S69-N73 WeakPolarHBondContact O-CB 3.38Å; S69-N73 PolarHBondContact O-N 2.98Å; S69-N73 PolarHBondContact O-ND2 2.91Å; S69-N73 PolarHBondContact OG-ND2 3.47Å
70	V	95.3	Very high	91.9	Very high	29 Å²	29	45.7 Å²	45.7	18%	0.176	24%	0.242	C	C	.	.	H	α-helix	trans	-63	-53.7	-179.4	172.4	0	0	0	0	110.7	F66 L67 L74 L102 A105	F66-V70 HydrophobicContact CD2-CG2 4.16Å; F66-V70 HydrophobicContact CE1-CG2 4.29Å; F66-V70 HydrophobicContact CE2-CG2 3.81Å; F66-V70 HydrophobicContact CZ-CG2 3.89Å; F66-V70 WeakPolarHBondContact O-CG2 3.27Å; F66-V70 PolarHBondContact O-N 2.95Å; L67-V70 PolarHBondContact O-N 3.36Å; V70-L74 WeakPolarHBondContact O-CB 3.13Å; V70-L74 PolarHBondContact O-N 3.5Å; V70-L102 HydrophobicContact CB-CD1 4.43Å; V70-L102 HydrophobicContact CG1-CD1 4.26Å; V70-L102 HydrophobicContact CG2-CD1 4.34Å; V70-A105 HydrophobicContact CG2-CB 3.81Å
71	F	93.8	Very high	91.7	Very high	139 Å²	139	45.5 Å²	45.5	61%	0.61	24%	0.239	S	C	*	.	H	α-helix	trans	-66.8	-42	-177.9	-72.3	-65	0	0	0	112.1	L67 L75	L67-F71 HydrophobicContact CB-CD2 4.16Å; L67-F71 HydrophobicContact CB-CE2 4.26Å; L67-F71 HydrophobicContact CD2-CD2 4.46Å; L67-F71 HydrophobicContact CD2-CE2 3.77Å; L67-F71 WeakPolarHBondContact O-CB 3.34Å; L67-F71 WeakPolarHBondContact O-CD2 3.26Å; L67-F71 PolarHBondContact O-N 3.45Å; F71-L75 WeakPolarHBondContact O-CB 3.49Å; F71-L75 PolarHBondContact O-N 3.26Å
72	G	92.6	Very high	91.4	Very high	16 Å²	16	48.5 Å²	48.5	17%	0.165	26%	0.255	C	S	.	.	H	α-helix	trans	-63.5	-50.9	-179.7	0	0	0	0	0	112.3	L68 L75 I76	L68-G72 WeakPolarHBondContact O-CA 3.43Å; L68-G72 PolarHBondContact O-N 3.46Å; G72-L75 PolarHBondContact O-N 2.89Å; G72-I76 WeakPolarHBondContact O-CG1 3.31Å; G72-I76 PolarHBondContact O-N 3.01Å; G72-I76 VanDerWaalsContact O-N 3.13Å
73	N	94.7	Very high	90.9	Very high	1 Å²	1	49.9 Å²	49.9	1%	0.005	26%	0.263	C	S	.	.	H	α-helix	trans	-70.6	-37.6	-178.9	-71.4	-60.1	0	0	0	112.1	S69 L75 I76 I77 A98 D101 L102 A383 P387	S69-N73 VanDerWaalsContact O-CB 3.25Å; S69-N73 WeakPolarHBondContact O-CB 3.38Å; S69-N73 PolarHBondContact O-N 2.98Å; S69-N73 PolarHBondContact O-ND2 2.91Å; S69-N73 PolarHBondContact OG-ND2 3.47Å; N73-L75 VanDerWaalsContact C-N 3.32Å; N73-L75 PolarHBondContact O-N 2.95Å; N73-I76 PolarHBondContact O-N 2.95Å; N73-I77 WeakPolarHBondContact O-CG1 3.46Å; N73-I77 PolarHBondContact O-N 3.18Å; N73-A98 HydrophobicContact CB-CB 4.19Å; N73-D101 WeakPolarHBondContact ND2-CB 3.43Å; N73-L102 HydrophobicContact CB-CB 4.48Å; N73-A383 PolarHBondContact ND2-O 2.86Å; N73-P387 VanDerWaalsContact OD1-CG 3.28Å; N73-P387 WeakPolarHBondContact OD1-CG 3.48Å
74	L	94.1	Very high	90.3	Very high	83 Å²	83	55.1 Å²	55.1	44%	0.435	28%	0.279	S	S	.	.	H	α-helix	trans	-61.8	-41	173.2	-175.4	63	0	0	0	111.7	V70 I76 I77 V78	V70-L74 WeakPolarHBondContact O-CB 3.13Å; V70-L74 PolarHBondContact O-N 3.5Å; L74-I76 PolarHBondContact O-N 2.85Å; L74-I77 PolarHBondContact O-N 3.46Å; L74-V78 HydrophobicContact CD1-CG2 4.45Å; L74-V78 HydrophobicContact CG-CG2 4.47Å; L74-V78 WeakPolarHBondContact O-CG2 3.2Å; L74-V78 PolarHBondContact O-N 2.8Å
75	L	90.8	Very high	89.3	Confident	48 Å²	48	62.8 Å²	62.8	25%	0.251	30%	0.302	S	S	.	.	H	α-helix	trans	-62.3	-41.6	176.8	-178	60.8	0	0	0	111.9	F71 G72 N73 V78 V79 L401 F405	F71-L75 WeakPolarHBondContact O-CB 3.49Å; F71-L75 PolarHBondContact O-N 3.26Å; G72-L75 PolarHBondContact O-N 2.89Å; N73-L75 VanDerWaalsContact C-N 3.32Å; N73-L75 PolarHBondContact O-N 2.95Å; L75-V78 PolarHBondContact O-N 2.94Å; L75-V79 HydrophobicContact CD1-CG2 3.94Å; L75-V79 HydrophobicContact CG-CG2 4.33Å; L75-V79 WeakPolarHBondContact O-CB 3.35Å; L75-V79 VanDerWaalsContact O-CG2 3.25Å; L75-V79 WeakPolarHBondContact O-CG2 3.18Å; L75-V79 PolarHBondContact O-N 3.14Å; L75-L401 HydrophobicContact CD2-CD1 3.57Å; L75-L401 HydrophobicContact CG-CD1 4.14Å; L75-F405 HydrophobicContact CD1-CE2 4.1Å; L75-F405 HydrophobicContact CD1-CZ 3.99Å
76	I	91.1	Very high	88.3	Confident	5 Å²	5	63.7 Å²	63.7	3%	0.026	31%	0.306	C	S	.	.	H	α-helix	trans	-57.9	-50.8	173.2	-66.3	172	0	0	0	110.6	G72 N73 L74 V78 V79 L80 A98 P387 Y390 F397	G72-I76 WeakPolarHBondContact O-CG1 3.31Å; G72-I76 PolarHBondContact O-N 3.01Å; G72-I76 VanDerWaalsContact O-N 3.13Å; N73-I76 PolarHBondContact O-N 2.95Å; L74-I76 PolarHBondContact O-N 2.85Å; I76-V78 VanDerWaalsContact C-N 3.35Å; I76-V78 PolarHBondContact O-N 3.01Å; I76-V79 PolarHBondContact O-N 3.35Å; I76-L80 HydrophobicContact CG2-CD1 3.65Å; I76-L80 HydrophobicContact CG2-CG 4.22Å; I76-L80 WeakPolarHBondContact O-CB 3.29Å; I76-L80 VanDerWaalsContact O-CG 3.27Å; I76-L80 WeakPolarHBondContact O-CG 3.42Å; I76-L80 PolarHBondContact O-N 2.9Å; I76-A98 HydrophobicContact CB-CB 4.14Å; I76-A98 HydrophobicContact CD1-CB 4.46Å; I76-A98 HydrophobicContact CG2-CB 3.95Å; I76-P387 HydrophobicContact CD1-CB 3.79Å; I76-P387 HydrophobicContact CD1-CG 3.78Å; I76-P387 HydrophobicContact CG1-CB 4.42Å; I76-Y390 HydrophobicContact CD1-CD2 4.19Å; I76-F397 HydrophobicContact CB-CZ 4.47Å; I76-F397 HydrophobicContact CG1-CE2 4.44Å; I76-F397 HydrophobicContact CG1-CZ 3.94Å
77	I	92	Very high	87.5	Confident	34 Å²	34	65.4 Å²	65.4	17%	0.174	31%	0.311	C	S	.	.	H	α-helix	trans	-56.2	-51.1	-179.6	-67.2	164.6	0	0	0	109.9	N73 L74 L80 M81 L95 A98 V99 L102	N73-I77 WeakPolarHBondContact O-CG1 3.46Å; N73-I77 PolarHBondContact O-N 3.18Å; L74-I77 PolarHBondContact O-N 3.46Å; I77-L80 PolarHBondContact O-N 2.62Å; I77-M81 HydrophobicContact CG2-CG 4.32Å; I77-M81 WeakPolarHBondContact O-CB 3.49Å; I77-M81 WeakPolarHBondContact O-CG 3.46Å; I77-M81 PolarHBondContact O-N 2.89Å; I77-L95 HydrophobicContact CB-CD1 4.13Å; I77-L95 HydrophobicContact CG1-CD1 3.84Å; I77-L95 HydrophobicContact CG2-CD1 4.11Å; I77-A98 HydrophobicContact CD1-CB 4.31Å; I77-A98 HydrophobicContact CG1-CB 3.89Å; I77-V99 HydrophobicContact CD1-CG2 4.18Å; I77-L102 HydrophobicContact CD1-CD2 4.09Å
78	V	89.9	Confident	87.1	Confident	59 Å²	59	64.3 Å²	64.3	36%	0.358	31%	0.308	S	S	.	.	H	α-helix	trans	-61.4	-49	-179.2	171.1	0	0	0	0	111.8	L74 L75 I76 L80 M81 L82	L74-V78 HydrophobicContact CD1-CG2 4.45Å; L74-V78 HydrophobicContact CG-CG2 4.47Å; L74-V78 WeakPolarHBondContact O-CG2 3.2Å; L74-V78 PolarHBondContact O-N 2.8Å; L75-V78 PolarHBondContact O-N 2.94Å; I76-V78 VanDerWaalsContact C-N 3.35Å; I76-V78 PolarHBondContact O-N 3.01Å; V78-L80 VanDerWaalsContact C-N 3.33Å; V78-L80 PolarHBondContact O-N 3.46Å; V78-M81 PolarHBondContact O-N 3.42Å; V78-L82 HydrophobicContact CG1-CD1 3.57Å; V78-L82 HydrophobicContact CG1-CG 4.23Å; V78-L82 WeakPolarHBondContact O-CB 3.31Å; V78-L82 VanDerWaalsContact O-CG 3.28Å; V78-L82 WeakPolarHBondContact O-CG 3.48Å; V78-L82 PolarHBondContact O-N 3.01Å
79	V	86.9	Confident	86.7	Confident	0 Å²	0	61.9 Å²	61.9	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-61.8	-40.8	-178.6	169.2	0	0	0	0	111.3	L75 I76 N83 F397 A400	L75-V79 HydrophobicContact CD1-CG2 3.94Å; L75-V79 HydrophobicContact CG-CG2 4.33Å; L75-V79 WeakPolarHBondContact O-CB 3.35Å; L75-V79 VanDerWaalsContact O-CG2 3.25Å; L75-V79 WeakPolarHBondContact O-CG2 3.18Å; L75-V79 PolarHBondContact O-N 3.14Å; I76-V79 PolarHBondContact O-N 3.35Å; V79-N83 WeakPolarHBondContact O-CB 3.47Å; V79-N83 PolarHBondContact O-N 2.89Å; V79-N83 PolarHBondContact O-ND2 3.1Å; V79-F397 HydrophobicContact CB-CE2 4.28Å; V79-F397 HydrophobicContact CB-CZ 4.21Å; V79-F397 HydrophobicContact CG1-CD2 4.41Å; V79-F397 HydrophobicContact CG1-CE2 3.91Å; V79-F397 HydrophobicContact CG1-CZ 4.14Å; V79-F397 HydrophobicContact CG2-CZ 4.5Å; V79-A400 HydrophobicContact CG1-CB 3.94Å
80	L	86.6	Confident	86.2	Confident	9 Å²	9	62.4 Å²	62.4	5%	0.047	30%	0.299	C	S	.	.	H	α-helix	trans	-72.8	-35.6	179.4	-67.6	-178.7	0	0	0	112.7	I76 I77 V78 M86 N91 L94 L95	I76-L80 HydrophobicContact CG2-CD1 3.65Å; I76-L80 HydrophobicContact CG2-CG 4.22Å; I76-L80 WeakPolarHBondContact O-CB 3.29Å; I76-L80 VanDerWaalsContact O-CG 3.27Å; I76-L80 WeakPolarHBondContact O-CG 3.42Å; I76-L80 PolarHBondContact O-N 2.9Å; I77-L80 PolarHBondContact O-N 2.62Å; V78-L80 VanDerWaalsContact C-N 3.33Å; V78-L80 PolarHBondContact O-N 3.46Å; L80-M86 HydrophobicContact CD2-CB 4.38Å; L80-N91 HydrophobicContact CD1-CB 4.45Å; L80-N91 WeakPolarHBondContact CD1-O 3.31Å; L80-N91 HydrophobicContact CD2-CB 3.91Å; L80-L94 HydrophobicContact CD1-CB 4.28Å; L80-L95 HydrophobicContact CD1-CB 4.12Å
81	M	85.1	Confident	85.9	Confident	103 Å²	103	61.9 Å²	61.9	51%	0.507	30%	0.295	S	S	.	.	H	α-helix	trans	-71.7	-41.9	179.4	-73.1	-62.7	-76.5	0	0	112.7	I77 V78 R87 L95	I77-M81 HydrophobicContact CG2-CG 4.32Å; I77-M81 WeakPolarHBondContact O-CB 3.49Å; I77-M81 WeakPolarHBondContact O-CG 3.46Å; I77-M81 PolarHBondContact O-N 2.89Å; V78-M81 PolarHBondContact O-N 3.42Å; M81-R87 PolarHBondContact O-NH2 2.99Å; M81-L95 HydrophobicContact SD-CD2 4.41Å
82	L	83.6	Confident	85.7	Confident	104 Å²	104	55.8 Å²	55.8	55%	0.545	27%	0.27	S	S	.	.	H	α-helix	trans	-72.4	-35.2	-179.7	-67.8	177.2	0	0	0	112.6	V78 K84 T404	V78-L82 HydrophobicContact CG1-CD1 3.57Å; V78-L82 HydrophobicContact CG1-CG 4.23Å; V78-L82 WeakPolarHBondContact O-CB 3.31Å; V78-L82 VanDerWaalsContact O-CG 3.28Å; V78-L82 WeakPolarHBondContact O-CG 3.48Å; V78-L82 PolarHBondContact O-N 3.01Å; L82-K84 PolarHBondContact O-N 3.32Å; L82-T404 HydrophobicContact CD1-CG2 3.74Å
83	N	79.8	Confident	85.7	Confident	37 Å²	37	55.4 Å²	55.4	20%	0.198	26%	0.264	C	S	.	.			trans	-92.1	86.6	-177.6	-68.2	-60.8	0	0	0	111.6	V79 R85 M86 T404	V79-N83 WeakPolarHBondContact O-CB 3.47Å; V79-N83 PolarHBondContact O-N 2.89Å; V79-N83 PolarHBondContact O-ND2 3.1Å; N83-R85 PolarHBondContact O-N 3.34Å; N83-M86 HydrophobicContact CB-CB 4.04Å; N83-M86 HydrophobicContact CB-CG 3.89Å; N83-M86 WeakPolarHBondContact O-CB 3.18Å; N83-M86 PolarHBondContact O-N 2.87Å; N83-T404 PolarHBondContact ND2-OG1 3.15Å
84	K	77.2	Confident	85.5	Confident	161 Å²	161	55.9 Å²	55.9	70%	0.7	27%	0.266	S	S	*	.	G	3₁₀ helix	trans	-51.1	-34.1	176.3	-70.7	-174.5	179.9	179.6	0	113.4	L82 M86 R87	L82-K84 PolarHBondContact O-N 3.32Å; K84-M86 PolarHBondContact O-N 3.35Å; K84-R87 WeakPolarHBondContact O-CB 3.46Å; K84-R87 WeakPolarHBondContact O-CG 3.37Å; K84-R87 PolarHBondContact O-N 3.4Å
85	R	72.8	Confident	85.4	Confident	248 Å²	248	54.2 Å²	54.2	94%	0.936	26%	0.257	S	S	*	.	G	3₁₀ helix	trans	-65.9	-20.1	177.8	-160.1	-179.8	-161.5	176.6	6.9	113.8	N83	N83-R85 PolarHBondContact O-N 3.34Å
86	M	72.1	Confident	85.6	Confident	32 Å²	32	52.3 Å²	52.3	16%	0.158	25%	0.248	C	C	.	.	G	3₁₀ helix	trans	-93.2	7.8	178.5	-68.6	-72.9	-77.8	0	0	112.4	L80 N83 K84 T88 N91 A400	L80-M86 HydrophobicContact CD2-CB 4.38Å; N83-M86 HydrophobicContact CB-CB 4.04Å; N83-M86 HydrophobicContact CB-CG 3.89Å; N83-M86 WeakPolarHBondContact O-CB 3.18Å; N83-M86 PolarHBondContact O-N 2.87Å; K84-M86 PolarHBondContact O-N 3.35Å; M86-T88 PolarHBondContact O-N 3.41Å; M86-N91 WeakPolarHBondContact O-CB 3.49Å; M86-N91 PolarHBondContact O-ND2 3.5Å; M86-A400 HydrophobicContact CE-CB 4.48Å
87	R	78.3	Confident	85.7	Confident	105 Å²	105	52.1 Å²	52.1	40%	0.396	25%	0.247	S	C	.	.			trans	-78.7	70.6	177.3	-64.3	179.5	-175.6	179.6	-1.4	111.8	M81 K84 R169	M81-R87 PolarHBondContact O-NH2 2.99Å; K84-R87 WeakPolarHBondContact O-CB 3.46Å; K84-R87 WeakPolarHBondContact O-CG 3.37Å; K84-R87 PolarHBondContact O-N 3.4Å; R87-R169 PolarHBondContact O-NE 3.16Å; R87-R169 PolarHBondContact O-NH2 2.88Å
88	T	84.9	Confident	85.9	Confident	63 Å²	63	50.6 Å²	50.6	39%	0.387	24%	0.24	S	C	.	.			trans	-100.7	161.7	174.6	62.9	0	0	0	0	110.7	M86 T90 N91 S92	M86-T88 PolarHBondContact O-N 3.41Å; T88-T90 VanDerWaalsContact C-N 3.34Å; T88-T90 PolarHBondContact O-N 3.43Å; T88-N91 PolarHBondContact O-N 2.91Å; T88-N91 WeakPolarHBondContact OG1-CB 3.44Å; T88-N91 VanDerWaalsContact OG1-CG 3.23Å; T88-N91 PolarHBondContact OG1-N 2.85Å; T88-N91 PolarHBondContact OG1-ND2 2.85Å; T88-S92 PolarHBondContact O-N 2.92Å; T88-S92 PolarHBondContact O-OG 3.4Å
89	V	84.4	Confident	86.2	Confident	24 Å²	24	50.4 Å²	50.4	15%	0.145	24%	0.239	C	C	.	.	H	α-helix	trans	-50.1	-51.1	177.3	171.6	0	0	0	0	111.4	N91 S92 F93 E152 R169 A172	V89-N91 VanDerWaalsContact C-N 3.31Å; V89-N91 PolarHBondContact O-N 3.43Å; V89-S92 WeakPolarHBondContact O-CB 3.25Å; V89-S92 PolarHBondContact O-N 3.43Å; V89-F93 HydrophobicContact CG1-CD2 4.44Å; V89-F93 HydrophobicContact CG1-CE2 3.93Å; V89-F93 WeakPolarHBondContact O-CD2 3.45Å; V89-F93 PolarHBondContact O-N 2.91Å; V89-E152 HydrophobicContact CG1-CG 4.03Å; V89-R169 HydrophobicContact CG2-CG 4.39Å; V89-A172 HydrophobicContact CB-CB 4.39Å; V89-A172 HydrophobicContact CG1-CB 3.75Å; V89-A172 HydrophobicContact CG2-CB 4.43Å
90	T	84.5	Confident	86.7	Confident	11 Å²	11	50.4 Å²	50.4	7%	0.067	24%	0.239	C	C	.	.	H	α-helix	trans	-60	-41.5	177.5	-43.6	0	0	0	0	112.5	T88 S92 F93 L94 E152 R153	T88-T90 VanDerWaalsContact C-N 3.34Å; T88-T90 PolarHBondContact O-N 3.43Å; T90-S92 PolarHBondContact O-N 3.3Å; T90-F93 WeakPolarHBondContact O-CB 3.5Å; T90-F93 PolarHBondContact O-N 2.92Å; T90-L94 HydrophobicContact CG2-CG 4.42Å; T90-L94 WeakPolarHBondContact O-CG 3.48Å; T90-L94 PolarHBondContact O-N 2.87Å; T90-E152 WeakPolarHBondContact CB-OE2 3.28Å; T90-E152 WeakPolarHBondContact CG2-OE2 3.4Å; T90-E152 PolarHBondContact OG1-OE1 3Å; T90-E152 PolarHBondContact OG1-OE2 3.36Å; T90-R153 VanDerWaalsContact OG1-CZ 3.28Å; T90-R153 PolarHBondContact OG1-NH1 2.89Å; T90-R153 PolarHBondContact OG1-NH2 3.34Å
91	N	87.8	Confident	87.1	Confident	17 Å²	17	50 Å²	50	9%	0.091	24%	0.237	C	C	.	.	H	α-helix	trans	-69.7	-25.3	-176.3	-70.8	-1.6	0	0	0	111.7	L80 M86 T88 V89 L94 L95	L80-N91 HydrophobicContact CD1-CB 4.45Å; L80-N91 WeakPolarHBondContact CD1-O 3.31Å; L80-N91 HydrophobicContact CD2-CB 3.91Å; M86-N91 WeakPolarHBondContact O-CB 3.49Å; M86-N91 PolarHBondContact O-ND2 3.5Å; T88-N91 PolarHBondContact O-N 2.91Å; T88-N91 WeakPolarHBondContact OG1-CB 3.44Å; T88-N91 VanDerWaalsContact OG1-CG 3.23Å; T88-N91 PolarHBondContact OG1-N 2.85Å; T88-N91 PolarHBondContact OG1-ND2 2.85Å; V89-N91 VanDerWaalsContact C-N 3.31Å; V89-N91 PolarHBondContact O-N 3.43Å; N91-L94 PolarHBondContact O-N 3.28Å; N91-L95 WeakPolarHBondContact O-CB 3.5Å; N91-L95 PolarHBondContact O-N 3.13Å
92	S	90.5	Very high	87.6	Confident	11 Å²	11	46.7 Å²	46.7	8%	0.077	22%	0.221	C	C	.	.	H	α-helix	trans	-64.7	-40.1	167.9	-62.4	0	0	0	0	112.2	T88 V89 T90 L95 S96	T88-S92 PolarHBondContact O-N 2.92Å; T88-S92 PolarHBondContact O-OG 3.4Å; V89-S92 WeakPolarHBondContact O-CB 3.25Å; V89-S92 PolarHBondContact O-N 3.43Å; T90-S92 PolarHBondContact O-N 3.3Å; S92-L95 WeakPolarHBondContact O-CB 3.3Å; S92-L95 PolarHBondContact O-N 3.41Å; S92-S96 PolarHBondContact O-N 3.05Å
93	F	91.9	Very high	88.2	Confident	8 Å²	8	43.1 Å²	43.1	4%	0.035	20%	0.202	C	C	.	.	H	α-helix	trans	-67.3	-39.9	173.8	-68.6	-65	0	0	0	112.5	V89 T90 L95 S96 L97 A148 I149 E152 A172 V175 I176	V89-F93 HydrophobicContact CG1-CD2 4.44Å; V89-F93 HydrophobicContact CG1-CE2 3.93Å; V89-F93 WeakPolarHBondContact O-CD2 3.45Å; V89-F93 PolarHBondContact O-N 2.91Å; T90-F93 WeakPolarHBondContact O-CB 3.5Å; T90-F93 PolarHBondContact O-N 2.92Å; F93-L95 VanDerWaalsContact C-N 3.27Å; F93-L95 PolarHBondContact O-N 3.34Å; F93-S96 WeakPolarHBondContact O-CB 3.21Å; F93-S96 PolarHBondContact O-N 3.3Å; F93-L97 PolarHBondContact O-N 2.84Å; F93-A148 HydrophobicContact CD1-CB 4.03Å; F93-A148 HydrophobicContact CE1-CB 3.7Å; F93-A148 HydrophobicContact CZ-CB 4.2Å; F93-I149 HydrophobicContact CB-CD1 4.06Å; F93-I149 HydrophobicContact CB-CG1 3.56Å; F93-I149 HydrophobicContact CG-CG1 4.19Å; F93-E152 HydrophobicContact CE2-CB 4.27Å; F93-E152 HydrophobicContact CE2-CG 4.28Å; F93-A172 HydrophobicContact CE2-CB 4.32Å; F93-A172 HydrophobicContact CZ-CB 4.32Å; F93-V175 HydrophobicContact CE1-CB 4.17Å; F93-V175 HydrophobicContact CE1-CG1 3.83Å; F93-V175 HydrophobicContact CZ-CB 4.2Å; F93-V175 HydrophobicContact CZ-CG1 4.09Å; F93-I176 HydrophobicContact CD1-CD1 4.03Å; F93-I176 HydrophobicContact CD1-CG1 3.65Å; F93-I176 HydrophobicContact CE1-CD1 4.26Å; F93-I176 HydrophobicContact CE1-CG1 3.65Å
94	L	90.8	Very high	88.8	Confident	12 Å²	12	41.4 Å²	41.4	6%	0.063	19%	0.192	C	C	.	.	H	α-helix	trans	-62.5	-36.2	174.1	-64.7	-179.6	0	0	0	112.1	L80 T90 N91 A98 I149 Y390	L80-L94 HydrophobicContact CD1-CB 4.28Å; T90-L94 HydrophobicContact CG2-CG 4.42Å; T90-L94 WeakPolarHBondContact O-CG 3.48Å; T90-L94 PolarHBondContact O-N 2.87Å; N91-L94 PolarHBondContact O-N 3.28Å; L94-A98 WeakPolarHBondContact O-CB 3.3Å; L94-A98 PolarHBondContact O-N 3.42Å; L94-I149 HydrophobicContact CD2-CD1 4.18Å; L94-Y390 HydrophobicContact CD2-CD1 3.94Å; L94-Y390 HydrophobicContact CD2-CD2 4.2Å; L94-Y390 HydrophobicContact CD2-CE1 3.42Å; L94-Y390 VanDerWaalsContact CD2-CE1 3.42Å; L94-Y390 HydrophobicContact CD2-CE2 3.74Å; L94-Y390 HydrophobicContact CD2-CG 4.32Å
95	L	92.8	Very high	89.7	Confident	47 Å²	47	33.8 Å²	33.8	25%	0.246	16%	0.159	C	C	.	.	H	α-helix	trans	-65.3	-45.6	173.9	-177.4	67.2	0	0	0	111.1	I77 L80 M81 N91 S92 F93 L97 A98 V99	I77-L95 HydrophobicContact CB-CD1 4.13Å; I77-L95 HydrophobicContact CG1-CD1 3.84Å; I77-L95 HydrophobicContact CG2-CD1 4.11Å; L80-L95 HydrophobicContact CD1-CB 4.12Å; M81-L95 HydrophobicContact SD-CD2 4.41Å; N91-L95 WeakPolarHBondContact O-CB 3.5Å; N91-L95 PolarHBondContact O-N 3.13Å; S92-L95 WeakPolarHBondContact O-CB 3.3Å; S92-L95 PolarHBondContact O-N 3.41Å; F93-L95 VanDerWaalsContact C-N 3.27Å; F93-L95 PolarHBondContact O-N 3.34Å; L95-L97 VanDerWaalsContact C-N 3.32Å; L95-L97 PolarHBondContact O-N 2.93Å; L95-A98 PolarHBondContact O-N 3.07Å; L95-V99 WeakPolarHBondContact O-CG2 3.39Å; L95-V99 PolarHBondContact O-N 2.76Å
96	S	94.6	Very high	90.7	Very high	8 Å²	8	25.5 Å²	25.5	6%	0.056	13%	0.133	C	C	.	.	H	α-helix	trans	-57.9	-44.8	175.7	-174.2	0	0	0	0	111.8	S92 F93 V99 S100 W180	S92-S96 PolarHBondContact O-N 3.05Å; F93-S96 WeakPolarHBondContact O-CB 3.21Å; F93-S96 PolarHBondContact O-N 3.3Å; S96-V99 PolarHBondContact O-N 3.22Å; S96-S100 PolarHBondContact O-N 3.4Å; S96-S100 VanDerWaalsContact O-N 3.09Å; S96-S100 PolarHBondContact O-OG 3.38Å; S96-W180 PolarHBondContact OG-NE1 3.46Å; S96-W180 VanDerWaalsContact OG-NE1 3.08Å
97	L	94	Very high	91.5	Very high	2 Å²	2	28.3 Å²	28.3	1%	0.01	14%	0.144	C	C	.	.	H	α-helix	trans	-62.4	-42.7	177.5	-173.8	65.8	0	0	0	112	F93 L95 V99 S100 D101 L146 I149 N386 Y390	F93-L97 PolarHBondContact O-N 2.84Å; L95-L97 VanDerWaalsContact C-N 3.32Å; L95-L97 PolarHBondContact O-N 2.93Å; L97-V99 VanDerWaalsContact C-N 3.29Å; L97-V99 PolarHBondContact O-N 3.15Å; L97-S100 PolarHBondContact O-N 3.45Å; L97-S100 PolarHBondContact O-OG 3.09Å; L97-D101 WeakPolarHBondContact O-CB 3.41Å; L97-D101 VanDerWaalsContact O-CG 3.3Å; L97-D101 PolarHBondContact O-N 3.11Å; L97-L146 HydrophobicContact CD2-CD2 4.14Å; L97-I149 HydrophobicContact CD2-CD1 4.47Å; L97-N386 HydrophobicContact CD2-CB 4.49Å; L97-Y390 HydrophobicContact CD2-CE2 3.96Å; L97-Y390 VanDerWaalsContact CD2-OH 3.28Å; L97-Y390 WeakPolarHBondContact CD2-OH 3.38Å
98	A	95.4	Very high	92.1	Very high	1 Å²	1	23.3 Å²	23.3	1%	0.008	13%	0.125	C	C	.	.	H	α-helix	trans	-64.7	-33.4	177	0	0	0	0	0	112.6	N73 I76 I77 L94 L95 L102	N73-A98 HydrophobicContact CB-CB 4.19Å; I76-A98 HydrophobicContact CB-CB 4.14Å; I76-A98 HydrophobicContact CD1-CB 4.46Å; I76-A98 HydrophobicContact CG2-CB 3.95Å; I77-A98 HydrophobicContact CD1-CB 4.31Å; I77-A98 HydrophobicContact CG1-CB 3.89Å; L94-A98 WeakPolarHBondContact O-CB 3.3Å; L94-A98 PolarHBondContact O-N 3.42Å; L95-A98 PolarHBondContact O-N 3.07Å; A98-L102 VanDerWaalsContact O-CB 3.26Å; A98-L102 WeakPolarHBondContact O-CB 3.5Å; A98-L102 PolarHBondContact O-N 2.85Å
99	V	96.1	Very high	92.4	Very high	56 Å²	56	20.4 Å²	20.4	34%	0.339	11%	0.108	S	C	.	.	H	α-helix	trans	-69.3	-44.4	175.9	172.9	0	0	0	0	111.3	I77 L95 S96 L97 L102 M103 W180	I77-V99 HydrophobicContact CD1-CG2 4.18Å; L95-V99 WeakPolarHBondContact O-CG2 3.39Å; L95-V99 PolarHBondContact O-N 2.76Å; S96-V99 PolarHBondContact O-N 3.22Å; L97-V99 VanDerWaalsContact C-N 3.29Å; L97-V99 PolarHBondContact O-N 3.15Å; V99-L102 PolarHBondContact O-N 3.19Å; V99-M103 PolarHBondContact O-N 3.15Å; V99-W180 HydrophobicContact CB-CZ2 4.38Å; V99-W180 HydrophobicContact CG1-CH2 3.73Å; V99-W180 HydrophobicContact CG1-CZ2 3.81Å
100	S	96.9	Very high	92.6	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-66.7	-39.8	177.7	55.1	0	0	0	0	112.4	S96 L97 L102 M103 M104 S142	S96-S100 PolarHBondContact O-N 3.4Å; S96-S100 VanDerWaalsContact O-N 3.09Å; S96-S100 PolarHBondContact O-OG 3.38Å; L97-S100 PolarHBondContact O-N 3.45Å; L97-S100 PolarHBondContact O-OG 3.09Å; S100-L102 VanDerWaalsContact C-N 3.34Å; S100-L102 PolarHBondContact O-N 3.44Å; S100-M103 WeakPolarHBondContact O-CB 3.28Å; S100-M103 PolarHBondContact O-N 3.09Å; S100-M104 PolarHBondContact O-N 3.04Å; S100-S142 WeakPolarHBondContact CB-OG 3.22Å; S100-S142 PolarHBondContact OG-OG 3.35Å
101	D	96	Very high	92.9	Very high	1 Å²	1	22.9 Å²	22.9	1%	0.005	12%	0.119	C	C	.	.	H	α-helix	trans	-68.6	-33.4	177.3	-69.5	-15.5	0	0	0	112	N73 L97 M104 A105 S142 A383 N386	N73-D101 WeakPolarHBondContact ND2-CB 3.43Å; L97-D101 WeakPolarHBondContact O-CB 3.41Å; L97-D101 VanDerWaalsContact O-CG 3.3Å; L97-D101 PolarHBondContact O-N 3.11Å; D101-M104 PolarHBondContact O-N 3.49Å; D101-A105 WeakPolarHBondContact O-CB 3.45Å; D101-A105 PolarHBondContact O-N 3.1Å; D101-S142 PolarHBondContact OD1-OG 3.15Å; D101-A383 HydrophobicContact CB-CB 4Å; D101-N386 PolarHBondContact OD2-ND2 3.25Å
102	L	95.9	Very high	92.8	Very high	33 Å²	33	23.2 Å²	23.2	17%	0.173	12%	0.122	C	C	.	.	H	α-helix	trans	-68.4	-38.9	172.5	-172.7	66	0	0	0	111.8	V70 N73 I77 A98 V99 S100 M104 A105 I106	V70-L102 HydrophobicContact CB-CD1 4.43Å; V70-L102 HydrophobicContact CG1-CD1 4.26Å; V70-L102 HydrophobicContact CG2-CD1 4.34Å; N73-L102 HydrophobicContact CB-CB 4.48Å; I77-L102 HydrophobicContact CD1-CD2 4.09Å; A98-L102 VanDerWaalsContact O-CB 3.26Å; A98-L102 WeakPolarHBondContact O-CB 3.5Å; A98-L102 PolarHBondContact O-N 2.85Å; V99-L102 PolarHBondContact O-N 3.19Å; S100-L102 VanDerWaalsContact C-N 3.34Å; S100-L102 PolarHBondContact O-N 3.44Å; L102-M104 VanDerWaalsContact C-N 3.33Å; L102-A105 PolarHBondContact O-N 3.29Å; L102-I106 HydrophobicContact CD1-CD1 3.78Å; L102-I106 HydrophobicContact CD1-CG1 4.14Å; L102-I106 HydrophobicContact CD2-CD1 4.28Å; L102-I106 HydrophobicContact CG-CD1 3.71Å; L102-I106 HydrophobicContact CG-CG1 4.34Å; L102-I106 WeakPolarHBondContact O-CG1 3.37Å; L102-I106 PolarHBondContact O-N 3.09Å
103	M	95.2	Very high	92.6	Very high	29 Å²	29	24 Å²	24	14%	0.143	13%	0.125	C	C	.	.	H	α-helix	trans	-60.1	-44.5	173.3	-175.8	167.6	70.6	0	0	110.9	V99 S100 F107 L134 V137 S138 I141	V99-M103 PolarHBondContact O-N 3.15Å; S100-M103 WeakPolarHBondContact O-CB 3.28Å; S100-M103 PolarHBondContact O-N 3.09Å; M103-F107 HydrophobicContact CG-CD2 4.05Å; M103-F107 WeakPolarHBondContact O-CB 3.4Å; M103-F107 PolarHBondContact O-N 2.81Å; M103-L134 HydrophobicContact SD-CD2 3.92Å; M103-V137 HydrophobicContact CE-CB 4.26Å; M103-V137 HydrophobicContact CE-CG1 3.77Å; M103-S138 WeakPolarHBondContact CE-OG 3.4Å; M103-S138 WeakPolarHBondContact CG-OG 3.37Å; M103-I141 HydrophobicContact CE-CD1 4.2Å
104	M	93.6	Very high	92.3	Very high	1 Å²	1	26.8 Å²	26.8	1%	0.005	14%	0.14	C	C	.	.	H	α-helix	trans	-59.7	-46.1	173.1	-176.2	173.8	-74.8	0	0	112.2	S100 D101 L102 C108 M109 S138 V139 W346 Y380 A383	S100-M104 PolarHBondContact O-N 3.04Å; D101-M104 PolarHBondContact O-N 3.49Å; L102-M104 VanDerWaalsContact C-N 3.33Å; M104-C108 HydrophobicContact CG-CB 4.32Å; M104-C108 WeakPolarHBondContact O-CA 3.46Å; M104-C108 WeakPolarHBondContact O-CB 3.2Å; M104-C108 PolarHBondContact O-N 2.93Å; M104-M109 HydrophobicContact CG-CE 4.33Å; M104-M109 PolarHBondContact O-N 2.94Å; M104-S138 PolarHBondContact N-OG 3.41Å; M104-V139 HydrophobicContact CE-CB 4.33Å; M104-V139 HydrophobicContact CE-CG2 3.36Å; M104-W346 HydrophobicContact CE-CH2 3.93Å; M104-W346 HydrophobicContact CE-CZ2 4.44Å; M104-Y380 HydrophobicContact CG-CD1 4.17Å; M104-Y380 HydrophobicContact CG-CE1 4.31Å; M104-Y380 HydrophobicContact SD-CD1 3.92Å; M104-Y380 HydrophobicContact SD-CE1 4.36Å; M104-A383 HydrophobicContact SD-CB 4.21Å
105	A	94.6	Very high	92.1	Very high	0 Å²	0	27 Å²	27	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-63.4	-45.7	-178.5	0	0	0	0	0	112.5	F66 V70 D101 L102 M109 P110	F66-A105 WeakPolarHBondContact CD2-O 3.39Å; F66-A105 VanDerWaalsContact CE2-O 3.27Å; F66-A105 WeakPolarHBondContact CE2-O 3.01Å; V70-A105 HydrophobicContact CG2-CB 3.81Å; D101-A105 WeakPolarHBondContact O-CB 3.45Å; D101-A105 PolarHBondContact O-N 3.1Å; L102-A105 PolarHBondContact O-N 3.29Å; A105-M109 HydrophobicContact CB-CE 4.26Å; A105-M109 HydrophobicContact CB-SD 4.36Å; A105-P110 VanDerWaalsContact O-CD 3.27Å; A105-P110 WeakPolarHBondContact O-CD 3.46Å
106	I	93.3	Very high	91.5	Very high	74 Å²	74	28.9 Å²	28.9	38%	0.379	15%	0.152	S	C	.	.	H	α-helix	trans	-78.9	-46.1	-173.7	-64.4	174.5	0	0	0	111.8	L102	L102-I106 HydrophobicContact CD1-CD1 3.78Å; L102-I106 HydrophobicContact CD1-CG1 4.14Å; L102-I106 HydrophobicContact CD2-CD1 4.28Å; L102-I106 HydrophobicContact CG-CD1 3.71Å; L102-I106 HydrophobicContact CG-CG1 4.34Å; L102-I106 WeakPolarHBondContact O-CG1 3.37Å; L102-I106 PolarHBondContact O-N 3.09Å
107	F	90.8	Very high	90.9	Very high	92 Å²	92	32.2 Å²	32.2	40%	0.404	17%	0.169	S	C	.	.	H	α-helix	trans	-95.7	-19.1	-170.9	-67.5	-77.8	0	0	0	114.1	M103 F111 L134	M103-F107 HydrophobicContact CG-CD2 4.05Å; M103-F107 WeakPolarHBondContact O-CB 3.4Å; M103-F107 PolarHBondContact O-N 2.81Å; F107-F111 WeakPolarHBondContact O-CD2 3.23Å; F107-L134 HydrophobicContact CB-CB 4.44Å; F107-L134 HydrophobicContact CB-CD1 3.89Å; F107-L134 HydrophobicContact CD1-CD1 3.95Å; F107-L134 HydrophobicContact CD2-CD1 4.12Å; F107-L134 HydrophobicContact CG-CD1 3.72Å
108	C	90.4	Very high	90.4	Very high	0 Å²	0	36.8 Å²	36.8	0%	0	19%	0.192	C	C	.	.	T	Hydrogen-bonded Turn	trans	-107.7	-49.2	-173.4	-46.7	0	0	0	0	111.7	M104 F111 T112 M135	M104-C108 HydrophobicContact CG-CB 4.32Å; M104-C108 WeakPolarHBondContact O-CA 3.46Å; M104-C108 WeakPolarHBondContact O-CB 3.2Å; M104-C108 PolarHBondContact O-N 2.93Å; C108-F111 PolarHBondContact O-N 3.02Å; C108-T112 VanDerWaalsContact O-CB 3.28Å; C108-T112 WeakPolarHBondContact O-CB 3.22Å; C108-T112 PolarHBondContact O-N 3.41Å; C108-T112 PolarHBondContact O-OG1 3.34Å; C108-M135 HydrophobicContact CB-CB 4.23Å; C108-M135 HydrophobicContact CB-CG 4.34Å; C108-M135 WeakPolarHBondContact SG-CA 3.28Å; C108-M135 PolarHBondContact SG-N 3.26Å
109	M	90.5	Very high	89.8	Confident	2 Å²	2	38.9 Å²	38.9	1%	0.01	21%	0.214	C	C	.	.	H	α-helix	trans	-62.1	-50.4	-171.9	-57.4	-177.5	-172.2	0	0	113.4	I65 F66 M104 A105 F111 T112 L113 Y380 A383	I65-M109 HydrophobicContact CG2-CE 4.08Å; I65-M109 HydrophobicContact CG2-SD 4.12Å; F66-M109 HydrophobicContact CB-SD 4.32Å; F66-M109 HydrophobicContact CD2-CB 4.4Å; F66-M109 HydrophobicContact CD2-SD 4.47Å; M104-M109 HydrophobicContact CG-CE 4.33Å; M104-M109 PolarHBondContact O-N 2.94Å; A105-M109 HydrophobicContact CB-CE 4.26Å; A105-M109 HydrophobicContact CB-SD 4.36Å; M109-F111 PolarHBondContact O-N 3.4Å; M109-T112 PolarHBondContact O-N 3.39Å; M109-L113 VanDerWaalsContact O-CB 3.27Å; M109-L113 WeakPolarHBondContact O-CB 3.48Å; M109-L113 PolarHBondContact O-N 3.37Å; M109-Y380 HydrophobicContact CE-CD1 4.15Å; M109-Y380 HydrophobicContact CE-CG 4.14Å; M109-Y380 HydrophobicContact CG-CD1 4.2Å; M109-Y380 HydrophobicContact CG-CD2 4.4Å; M109-Y380 HydrophobicContact CG-CE1 4.47Å; M109-Y380 HydrophobicContact CG-CG 4.18Å; M109-A383 HydrophobicContact CE-CB 4.15Å
110	P	89.8	Confident	89.3	Confident	37 Å²	37	37.4 Å²	37.4	24%	0.24	20%	0.204	C	C	.	.	H	α-helix	trans	-65.1	-42.2	-179.7	-21.6	33.8	0	0	0	112.9	F66 A105 T112 L113 I114	F66-P110 HydrophobicContact CD2-CG 4.4Å; F66-P110 HydrophobicContact CE2-CG 3.99Å; A105-P110 VanDerWaalsContact O-CD 3.27Å; A105-P110 WeakPolarHBondContact O-CD 3.46Å; P110-T112 VanDerWaalsContact C-N 3.26Å; P110-T112 PolarHBondContact O-N 3.11Å; P110-L113 PolarHBondContact O-N 3.47Å; P110-I114 WeakPolarHBondContact O-CB 3.32Å; P110-I114 WeakPolarHBondContact O-CG1 3.43Å; P110-I114 PolarHBondContact O-N 3.45Å
111	F	90.3	Very high	89	Confident	49 Å²	49	38.1 Å²	38.1	22%	0.215	21%	0.208	C	C	.	.	H	α-helix	trans	-75.6	-13.8	-177.8	-64.5	-84.3	0	0	0	113.5	F107 C108 M109 P115 F123 V131	F107-F111 WeakPolarHBondContact O-CD2 3.23Å; C108-F111 PolarHBondContact O-N 3.02Å; M109-F111 PolarHBondContact O-N 3.4Å; F111-P115 WeakPolarHBondContact O-CD 3.36Å; F111-P115 VanDerWaalsContact O-CG 3.22Å; F111-P115 WeakPolarHBondContact O-CG 3.4Å; F111-F123 AromaticContact CD1-CD1 3.85Å; F111-F123 HydrophobicContact CD1-CD1 3.85Å; F111-F123 AromaticContact CD1-CD2 3.79Å; F111-F123 HydrophobicContact CD1-CD2 3.79Å; F111-F123 AromaticContact CD1-CE1 3.91Å; F111-F123 HydrophobicContact CD1-CE1 3.91Å; F111-F123 AromaticContact CD1-CE2 3.84Å; F111-F123 HydrophobicContact CD1-CE2 3.84Å; F111-F123 AromaticContact CD1-CG 3.79Å; F111-F123 HydrophobicContact CD1-CG 3.79Å; F111-F123 AromaticContact CD1-CZ 3.9Å; F111-F123 HydrophobicContact CD1-CZ 3.9Å; F111-F123 AromaticContact CE1-CD1 3.68Å; F111-F123 HydrophobicContact CE1-CD1 3.68Å; F111-F123 HydrophobicContact CE1-CD2 4.46Å; F111-F123 AromaticContact CE1-CE1 3.77Å; F111-F123 HydrophobicContact CE1-CE1 3.77Å; F111-F123 HydrophobicContact CE1-CG 4.04Å; F111-F123 HydrophobicContact CE1-CZ 4.2Å; F111-V131 HydrophobicContact CB-CB 4.37Å; F111-V131 HydrophobicContact CB-CG1 3.83Å; F111-V131 HydrophobicContact CB-CG2 3.62Å; F111-V131 HydrophobicContact CD1-CG2 4.18Å; F111-V131 HydrophobicContact CD2-CG2 4.2Å; F111-V131 HydrophobicContact CG-CG2 3.75Å
112	T	85.5	Confident	88.8	Confident	25 Å²	25	43 Å²	43	15%	0.153	23%	0.232	C	C	.	.	H	α-helix	trans	-90.2	-40.3	168.1	-54.3	0	0	0	0	110.9	C108 M109 P110 N116 Y380	C108-T112 VanDerWaalsContact O-CB 3.28Å; C108-T112 WeakPolarHBondContact O-CB 3.22Å; C108-T112 PolarHBondContact O-N 3.41Å; C108-T112 PolarHBondContact O-OG1 3.34Å; M109-T112 PolarHBondContact O-N 3.39Å; P110-T112 VanDerWaalsContact C-N 3.26Å; P110-T112 PolarHBondContact O-N 3.11Å; T112-N116 WeakPolarHBondContact O-CB 3.5Å; T112-N116 PolarHBondContact O-N 2.93Å; T112-N116 PolarHBondContact O-ND2 2.88Å; T112-Y380 PolarHBondContact OG1-OH 2.86Å
113	L	85.1	Confident	88.6	Confident	28 Å²	28	44.4 Å²	44.4	15%	0.147	24%	0.237	C	C	.	.	H	α-helix	trans	-67.5	-50	-176.6	179.8	62.8	0	0	0	112.6	Y62 M109 P110 N116 I117	Y62-L113 HydrophobicContact CD1-CB 4.25Å; Y62-L113 HydrophobicContact CD1-CD1 4.11Å; Y62-L113 HydrophobicContact CD1-CD2 4.39Å; Y62-L113 HydrophobicContact CD1-CG 4.48Å; Y62-L113 HydrophobicContact CD2-CD1 3.67Å; Y62-L113 HydrophobicContact CE2-CD1 4.15Å; Y62-L113 HydrophobicContact CG-CD1 3.67Å; Y62-L113 HydrophobicContact CG-CD2 4.16Å; Y62-L113 HydrophobicContact CG-CG 4.36Å; M109-L113 VanDerWaalsContact O-CB 3.27Å; M109-L113 WeakPolarHBondContact O-CB 3.48Å; M109-L113 PolarHBondContact O-N 3.37Å; P110-L113 PolarHBondContact O-N 3.47Å; L113-N116 PolarHBondContact O-N 2.92Å; L113-I117 HydrophobicContact CD1-CD1 3.66Å; L113-I117 HydrophobicContact CD1-CG1 4.1Å; L113-I117 HydrophobicContact CD2-CD1 4.39Å; L113-I117 HydrophobicContact CG-CD1 3.7Å; L113-I117 HydrophobicContact CG-CG1 4.46Å; L113-I117 WeakPolarHBondContact O-CG1 3.39Å; L113-I117 PolarHBondContact O-N 2.85Å
114	I	87.4	Confident	88.5	Confident	65 Å²	65	44.4 Å²	44.4	33%	0.333	25%	0.245	S	C	.	.	H	α-helix	trans	-59.7	-48.7	-173.7	-67.9	164.2	0	0	0	111.2	P110 N116 I117 L118 F123	P110-I114 WeakPolarHBondContact O-CB 3.32Å; P110-I114 WeakPolarHBondContact O-CG1 3.43Å; P110-I114 PolarHBondContact O-N 3.45Å; I114-N116 VanDerWaalsContact C-N 3.34Å; I114-N116 PolarHBondContact O-N 3.23Å; I114-I117 PolarHBondContact O-N 3.25Å; I114-L118 HydrophobicContact CG2-CD1 3.6Å; I114-L118 HydrophobicContact CG2-CG 4.33Å; I114-L118 WeakPolarHBondContact O-CB 3.47Å; I114-L118 WeakPolarHBondContact O-CG 3.33Å; I114-L118 PolarHBondContact O-N 2.87Å; I114-F123 HydrophobicContact CB-CE2 4.12Å; I114-F123 HydrophobicContact CB-CZ 4.08Å; I114-F123 HydrophobicContact CD1-CZ 3.8Å; I114-F123 HydrophobicContact CG2-CE2 4.05Å; I114-F123 HydrophobicContact CG2-CZ 3.91Å
115	P	85.4	Confident	88.5	Confident	17 Å²	17	47 Å²	47	11%	0.11	27%	0.266	C	S	.	.	H	α-helix	trans	-67.5	-31.9	177.7	-23.3	37.6	0	0	0	113.7	F111 I117 G119 D120 F121 F123	F111-P115 WeakPolarHBondContact O-CD 3.36Å; F111-P115 VanDerWaalsContact O-CG 3.22Å; F111-P115 WeakPolarHBondContact O-CG 3.4Å; P115-I117 VanDerWaalsContact C-N 3.3Å; P115-I117 PolarHBondContact O-N 3.45Å; P115-G119 VanDerWaalsContact O-CA 3.3Å; P115-G119 WeakPolarHBondContact O-CA 3.39Å; P115-G119 PolarHBondContact O-N 2.83Å; P115-D120 VanDerWaalsContact CA-O 3.3Å; P115-D120 WeakPolarHBondContact CA-O 3.45Å; P115-D120 WeakPolarHBondContact CB-O 3.46Å; P115-D120 PolarHBondContact O-N 3.32Å; P115-F121 HydrophobicContact CB-CB 4.37Å; P115-F121 HydrophobicContact CB-CD2 3.96Å; P115-F121 HydrophobicContact CG-CD2 3.52Å; P115-F121 HydrophobicContact CG-CE2 4.02Å; P115-F121 HydrophobicContact CG-CG 4.36Å; P115-F123 HydrophobicContact CG-CD2 4.24Å; P115-F123 HydrophobicContact CG-CE2 3.96Å
116	N	81.6	Confident	88.4	Confident	87 Å²	87	51.6 Å²	51.6	47%	0.465	29%	0.294	S	S	.	.	H	α-helix	trans	-65.5	-33.2	175.2	-80.2	-26.2	0	0	0	112.4	T112 L113 I114	T112-N116 WeakPolarHBondContact O-CB 3.5Å; T112-N116 PolarHBondContact O-N 2.93Å; T112-N116 PolarHBondContact O-ND2 2.88Å; L113-N116 PolarHBondContact O-N 2.92Å; I114-N116 VanDerWaalsContact C-N 3.34Å; I114-N116 PolarHBondContact O-N 3.23Å
117	I	81.6	Confident	88.4	Confident	78 Å²	78	51.3 Å²	51.3	40%	0.4	29%	0.292	S	S	.	.	H	α-helix	trans	-79.8	-45.4	176.6	-63.7	166.4	0	0	0	110.8	I59 L113 I114 P115 G119	I59-I117 HydrophobicContact CD1-CD1 3.94Å; I59-I117 HydrophobicContact CG1-CD1 3.59Å; I59-I117 HydrophobicContact CG1-CG1 4.44Å; L113-I117 HydrophobicContact CD1-CD1 3.66Å; L113-I117 HydrophobicContact CD1-CG1 4.1Å; L113-I117 HydrophobicContact CD2-CD1 4.39Å; L113-I117 HydrophobicContact CG-CD1 3.7Å; L113-I117 HydrophobicContact CG-CG1 4.46Å; L113-I117 WeakPolarHBondContact O-CG1 3.39Å; L113-I117 PolarHBondContact O-N 2.85Å; I114-I117 PolarHBondContact O-N 3.25Å; P115-I117 VanDerWaalsContact C-N 3.3Å; P115-I117 PolarHBondContact O-N 3.45Å; I117-G119 VanDerWaalsContact C-N 3.28Å; I117-G119 PolarHBondContact O-N 3.35Å
118	L	83.6	Confident	88.5	Confident	97 Å²	97	47 Å²	47	51%	0.508	27%	0.273	S	S	.	.	H	α-helix	trans	-76.2	-16.3	-176.6	-66.5	176.8	0	0	0	113.2	I114 D120 I122	I114-L118 HydrophobicContact CG2-CD1 3.6Å; I114-L118 HydrophobicContact CG2-CG 4.33Å; I114-L118 WeakPolarHBondContact O-CB 3.47Å; I114-L118 WeakPolarHBondContact O-CG 3.33Å; I114-L118 PolarHBondContact O-N 2.87Å; L118-D120 HydrophobicContact CB-CB 4.33Å; L118-D120 PolarHBondContact O-N 2.9Å; L118-I122 HydrophobicContact CD1-CD1 4.24Å
119	G	82	Confident	88.7	Confident	45 Å²	45	50.9 Å²	50.9	46%	0.464	29%	0.291	S	S	.	.	T	Hydrogen-bonded Turn	trans	58.2	29.8	-166.9	0	0	0	0	0	111.8	P115 I117	P115-G119 VanDerWaalsContact O-CA 3.3Å; P115-G119 WeakPolarHBondContact O-CA 3.39Å; P115-G119 PolarHBondContact O-N 2.83Å; I117-G119 VanDerWaalsContact C-N 3.28Å; I117-G119 PolarHBondContact O-N 3.35Å
120	D	86	Confident	88.9	Confident	26 Å²	26	53.9 Å²	53.9	14%	0.139	31%	0.306	C	S	.	.	S	Bend	trans	-155.4	129.6	-175.6	-152.1	-21	0	0	0	112.6	P115 L118 I122 K201 N208	P115-D120 VanDerWaalsContact CA-O 3.3Å; P115-D120 WeakPolarHBondContact CA-O 3.45Å; P115-D120 WeakPolarHBondContact CB-O 3.46Å; P115-D120 PolarHBondContact O-N 3.32Å; L118-D120 HydrophobicContact CB-CB 4.33Å; L118-D120 PolarHBondContact O-N 2.9Å; D120-I122 HydrophobicContact CB-CG2 4.26Å; D120-I122 PolarHBondContact O-N 3.4Å; D120-K201 VanDerWaalsContact CB-NZ 3.33Å; D120-K201 VanDerWaalsContact CG-NZ 3.28Å; D120-K201 IonicContact OD2-NZ 3.96Å; D120-K201 PolarHBondContact OD2-NZ 3.12Å; D120-N208 PolarHBondContact OD1-N 3.33Å
121	F	91.1	Very high	89	Confident	15 Å²	15	52.7 Å²	52.7	7%	0.066	30%	0.298	C	S	.	.			trans	-90.4	92.4	174.2	-165.2	-85.3	0	0	0	111	P115 F123 G124 M127 C128 L196 N208 C210	P115-F121 HydrophobicContact CB-CB 4.37Å; P115-F121 HydrophobicContact CB-CD2 3.96Å; P115-F121 HydrophobicContact CG-CD2 3.52Å; P115-F121 HydrophobicContact CG-CE2 4.02Å; P115-F121 HydrophobicContact CG-CG 4.36Å; F121-F123 HydrophobicContact CD1-CB 4.38Å; F121-F123 HydrophobicContact CE1-CB 3.65Å; F121-F123 HydrophobicContact CE1-CD2 4.37Å; F121-F123 HydrophobicContact CE2-CD2 4.11Å; F121-F123 HydrophobicContact CZ-CB 3.85Å; F121-F123 HydrophobicContact CZ-CD2 4.04Å; F121-F123 HydrophobicContact CZ-CG 4.43Å; F121-G124 WeakPolarHBondContact CE1-O 3.26Å; F121-M127 HydrophobicContact CE1-CB 4.38Å; F121-M127 HydrophobicContact CZ-CB 4.24Å; F121-C128 HydrophobicContact CD1-CB 4.49Å; F121-C128 HydrophobicContact CE1-CB 3.89Å; F121-C128 HydrophobicContact CZ-CB 4.14Å; F121-L196 HydrophobicContact CB-CD1 4.16Å; F121-L196 HydrophobicContact CD1-CD1 3.61Å; F121-L196 HydrophobicContact CE1-CD1 4.44Å; F121-L196 HydrophobicContact CG-CD1 4.17Å; F121-N208 WeakPolarHBondContact CB-O 3.24Å; F121-N208 PolarHBondContact N-O 3.29Å; F121-C210 HydrophobicContact CD1-CB 4.44Å; F121-C210 HydrophobicContact CD2-CB 3.97Å; F121-C210 HydrophobicContact CE2-CB 4.25Å; F121-C210 HydrophobicContact CG-CB 4.08Å
122	I	91.1	Very high	89.1	Confident	103 Å²	103	51.1 Å²	51.1	53%	0.528	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-8.5	-175.2	64.4	170.7	0	0	0	114.8	L118 D120 G124	L118-I122 HydrophobicContact CD1-CD1 4.24Å; D120-I122 HydrophobicContact CB-CG2 4.26Å; D120-I122 PolarHBondContact O-N 3.4Å; I122-G124 VanDerWaalsContact C-N 3.31Å; I122-G124 PolarHBondContact O-N 2.89Å
123	F	91.6	Very high	89.6	Confident	62 Å²	62	52.5 Å²	52.5	27%	0.272	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.4	-1.5	-170.7	-56.3	-76.6	0	0	0	114.8	F111 I114 P115 F121 M127	F111-F123 AromaticContact CD1-CD1 3.85Å; F111-F123 HydrophobicContact CD1-CD1 3.85Å; F111-F123 AromaticContact CD1-CD2 3.79Å; F111-F123 HydrophobicContact CD1-CD2 3.79Å; F111-F123 AromaticContact CD1-CE1 3.91Å; F111-F123 HydrophobicContact CD1-CE1 3.91Å; F111-F123 AromaticContact CD1-CE2 3.84Å; F111-F123 HydrophobicContact CD1-CE2 3.84Å; F111-F123 AromaticContact CD1-CG 3.79Å; F111-F123 HydrophobicContact CD1-CG 3.79Å; F111-F123 AromaticContact CD1-CZ 3.9Å; F111-F123 HydrophobicContact CD1-CZ 3.9Å; F111-F123 AromaticContact CE1-CD1 3.68Å; F111-F123 HydrophobicContact CE1-CD1 3.68Å; F111-F123 HydrophobicContact CE1-CD2 4.46Å; F111-F123 AromaticContact CE1-CE1 3.77Å; F111-F123 HydrophobicContact CE1-CE1 3.77Å; F111-F123 HydrophobicContact CE1-CG 4.04Å; F111-F123 HydrophobicContact CE1-CZ 4.2Å; I114-F123 HydrophobicContact CB-CE2 4.12Å; I114-F123 HydrophobicContact CB-CZ 4.08Å; I114-F123 HydrophobicContact CD1-CZ 3.8Å; I114-F123 HydrophobicContact CG2-CE2 4.05Å; I114-F123 HydrophobicContact CG2-CZ 3.91Å; P115-F123 HydrophobicContact CG-CD2 4.24Å; P115-F123 HydrophobicContact CG-CE2 3.96Å; F121-F123 HydrophobicContact CD1-CB 4.38Å; F121-F123 HydrophobicContact CE1-CB 3.65Å; F121-F123 HydrophobicContact CE1-CD2 4.37Å; F121-F123 HydrophobicContact CE2-CD2 4.11Å; F121-F123 HydrophobicContact CZ-CB 3.85Å; F121-F123 HydrophobicContact CZ-CD2 4.04Å; F121-F123 HydrophobicContact CZ-CG 4.43Å; F123-M127 HydrophobicContact CB-CB 3.63Å; F123-M127 HydrophobicContact CB-CG 4Å; F123-M127 WeakPolarHBondContact O-CB 3.33Å; F123-M127 WeakPolarHBondContact O-CG 3.38Å
124	G	92.8	Very high	90.1	Very high	29 Å²	29	52.8 Å²	52.8	30%	0.299	30%	0.298	S	S	.	.	H	α-helix	trans	79.4	173.1	176.7	0	0	0	0	0	115.5	F121 I122 T126 M127 C128	F121-G124 WeakPolarHBondContact CE1-O 3.26Å; I122-G124 VanDerWaalsContact C-N 3.31Å; I122-G124 PolarHBondContact O-N 2.89Å; G124-T126 VanDerWaalsContact C-N 3.35Å; G124-T126 PolarHBondContact O-N 3.18Å; G124-M127 PolarHBondContact O-N 3.01Å; G124-C128 PolarHBondContact O-N 3.29Å
125	A	93.2	Very high	90.4	Very high	55 Å²	55	51.4 Å²	51.4	46%	0.455	29%	0.291	S	S	.	.	H	α-helix	trans	-65.1	-34.8	-169.7	0	0	0	0	0	113.6	C128 K129 L196	A125-C128 WeakPolarHBondContact O-CB 3.38Å; A125-C128 PolarHBondContact O-N 2.9Å; A125-K129 PolarHBondContact O-N 3.17Å; A125-L196 HydrophobicContact CB-CB 4.18Å; A125-L196 HydrophobicContact CB-CD2 4.34Å
126	T	93.8	Very high	90.8	Very high	97 Å²	97	51 Å²	51	60%	0.595	29%	0.29	S	S	*	.	H	α-helix	trans	-64	-45.9	179.4	-51.5	0	0	0	0	111.6	G124 C128 K129 I130	G124-T126 VanDerWaalsContact C-N 3.35Å; G124-T126 PolarHBondContact O-N 3.18Å; T126-C128 VanDerWaalsContact C-N 3.35Å; T126-C128 PolarHBondContact O-N 3.43Å; T126-K129 PolarHBondContact O-N 3.47Å; T126-I130 HydrophobicContact CG2-CD1 3.79Å; T126-I130 WeakPolarHBondContact O-CG1 3.46Å; T126-I130 PolarHBondContact O-N 3.03Å
127	M	92.9	Very high	91.6	Very high	68 Å²	68	46.9 Å²	46.9	34%	0.335	27%	0.268	S	S	.	.	H	α-helix	trans	-69.2	-34	179.1	-70	-62.7	135.3	0	0	112.1	F121 F123 G124 K129 I130 V131	F121-M127 HydrophobicContact CE1-CB 4.38Å; F121-M127 HydrophobicContact CZ-CB 4.24Å; F123-M127 HydrophobicContact CB-CB 3.63Å; F123-M127 HydrophobicContact CB-CG 4Å; F123-M127 WeakPolarHBondContact O-CB 3.33Å; F123-M127 WeakPolarHBondContact O-CG 3.38Å; G124-M127 PolarHBondContact O-N 3.01Å; M127-K129 VanDerWaalsContact C-N 3.26Å; M127-K129 PolarHBondContact O-N 3.14Å; M127-I130 HydrophobicContact CE-CD1 3.99Å; M127-I130 PolarHBondContact O-N 3.49Å; M127-V131 VanDerWaalsContact O-CB 3.27Å; M127-V131 WeakPolarHBondContact O-CB 3.5Å; M127-V131 WeakPolarHBondContact O-CG2 3.12Å; M127-V131 PolarHBondContact O-N 3.06Å
128	C	93.8	Very high	92.2	Very high	1 Å²	1	43.2 Å²	43.2	1%	0.007	25%	0.249	C	C	.	.	H	α-helix	trans	-54.1	-43.6	172.8	169.7	0	0	0	0	111.8	F121 G124 A125 T126 A132 C210	F121-C128 HydrophobicContact CD1-CB 4.49Å; F121-C128 HydrophobicContact CE1-CB 3.89Å; F121-C128 HydrophobicContact CZ-CB 4.14Å; G124-C128 PolarHBondContact O-N 3.29Å; A125-C128 WeakPolarHBondContact O-CB 3.38Å; A125-C128 PolarHBondContact O-N 2.9Å; T126-C128 VanDerWaalsContact C-N 3.35Å; T126-C128 PolarHBondContact O-N 3.43Å; C128-A132 WeakPolarHBondContact O-CB 3.49Å; C128-A132 PolarHBondContact O-N 3.38Å; C128-C210 WeakPolarHBondContact CA-SG 3.13Å; C128-C210 HydrophobicContact CB-CB 3.74Å; C128-C210 WeakPolarHBondContact CB-SG 3.38Å; C128-C210 PolarHBondContact O-SG 3.16Å; C128-C210 VanDerWaalsContact SG-CA 3.57Å; C128-C210 WeakPolarHBondContact SG-CB 3.17Å; C128-C210 CovalentContact SG-SG 2.03Å; C128-C210 PolarHBondContact SG-SG 3.04Å
129	K	94.8	Very high	92.8	Very high	83 Å²	83	39 Å²	39	36%	0.361	23%	0.227	S	C	.	.	H	α-helix	trans	-72.8	-47.1	177.4	-66.2	-179.4	173.8	-143.9	0	112.9	A125 T126 M127 Y133 P191 N194	A125-K129 PolarHBondContact O-N 3.17Å; T126-K129 PolarHBondContact O-N 3.47Å; M127-K129 VanDerWaalsContact C-N 3.26Å; M127-K129 PolarHBondContact O-N 3.14Å; K129-Y133 VanDerWaalsContact O-CB 3.3Å; K129-Y133 WeakPolarHBondContact O-CB 3.39Å; K129-Y133 PolarHBondContact O-N 3.45Å; K129-P191 HydrophobicContact CB-CB 4.27Å; K129-P191 VanDerWaalsContact CD-O 3.28Å; K129-P191 WeakPolarHBondContact CD-O 3.42Å; K129-P191 WeakPolarHBondContact CE-O 3.32Å; K129-P191 PolarHBondContact NZ-O 3Å; K129-P191 VanDerWaalsContact NZ-O 3.11Å; K129-N194 WeakPolarHBondContact CE-O 3.47Å; K129-N194 HydrophobicContact CG-CB 4.43Å
130	I	94.1	Very high	93.5	Very high	64 Å²	64	36.9 Å²	36.9	33%	0.328	21%	0.205	S	C	.	.	H	α-helix	trans	-64.4	-46.9	-176.1	-69.2	173.1	0	0	0	111.2	T126 M127 Y133 L134	T126-I130 HydrophobicContact CG2-CD1 3.79Å; T126-I130 WeakPolarHBondContact O-CG1 3.46Å; T126-I130 PolarHBondContact O-N 3.03Å; M127-I130 HydrophobicContact CE-CD1 3.99Å; M127-I130 PolarHBondContact O-N 3.49Å; I130-Y133 PolarHBondContact O-N 2.92Å; I130-L134 HydrophobicContact CG2-CD1 3.68Å; I130-L134 HydrophobicContact CG2-CG 4.14Å; I130-L134 WeakPolarHBondContact O-CB 3.39Å; I130-L134 WeakPolarHBondContact O-CG 3.46Å; I130-L134 PolarHBondContact O-N 3.02Å
131	V	92.6	Very high	94	Very high	12 Å²	12	35.7 Å²	35.7	7%	0.073	20%	0.199	C	C	.	.	H	α-helix	trans	-63.6	-47.7	-176.9	171.6	0	0	0	0	110.6	F111 M127 Y133 L134 M135	F111-V131 HydrophobicContact CB-CB 4.37Å; F111-V131 HydrophobicContact CB-CG1 3.83Å; F111-V131 HydrophobicContact CB-CG2 3.62Å; F111-V131 HydrophobicContact CD1-CG2 4.18Å; F111-V131 HydrophobicContact CD2-CG2 4.2Å; F111-V131 HydrophobicContact CG-CG2 3.75Å; M127-V131 VanDerWaalsContact O-CB 3.27Å; M127-V131 WeakPolarHBondContact O-CB 3.5Å; M127-V131 WeakPolarHBondContact O-CG2 3.12Å; M127-V131 PolarHBondContact O-N 3.06Å; V131-Y133 VanDerWaalsContact C-N 3.33Å; V131-Y133 PolarHBondContact O-N 3.34Å; V131-L134 PolarHBondContact O-N 2.93Å; V131-M135 VanDerWaalsContact O-CB 3.24Å; V131-M135 WeakPolarHBondContact O-CB 3.2Å; V131-M135 PolarHBondContact O-N 3.45Å
132	A	92.2	Very high	94.2	Very high	17 Å²	17	35.3 Å²	35.3	14%	0.14	20%	0.198	C	C	.	.	H	α-helix	trans	-62.1	-41.1	178.2	0	0	0	0	0	112.1	C128 G136 Y190 N194	C128-A132 WeakPolarHBondContact O-CB 3.49Å; C128-A132 PolarHBondContact O-N 3.38Å; A132-G136 PolarHBondContact O-N 3.44Å; A132-G136 VanDerWaalsContact O-N 3.1Å; A132-Y190 HydrophobicContact CB-CD1 4.16Å; A132-N194 WeakPolarHBondContact CB-ND2 3.46Å
133	Y	95.6	Very high	94.4	Very high	54 Å²	54	30.5 Å²	30.5	21%	0.212	17%	0.173	C	C	.	.	H	α-helix	trans	-64.2	-53	176.6	-177.7	-119	0	0	0	112.3	K129 I130 V131 M135 G136 V137 L184 M187 P191	K129-Y133 VanDerWaalsContact O-CB 3.3Å; K129-Y133 WeakPolarHBondContact O-CB 3.39Å; K129-Y133 PolarHBondContact O-N 3.45Å; I130-Y133 PolarHBondContact O-N 2.92Å; V131-Y133 VanDerWaalsContact C-N 3.33Å; V131-Y133 PolarHBondContact O-N 3.34Å; Y133-M135 PolarHBondContact O-N 3.3Å; Y133-G136 PolarHBondContact O-N 2.95Å; Y133-V137 HydrophobicContact CD1-CG2 4.33Å; Y133-V137 HydrophobicContact CD2-CG2 4.03Å; Y133-V137 HydrophobicContact CE1-CG2 4.03Å; Y133-V137 HydrophobicContact CE2-CG2 3.71Å; Y133-V137 HydrophobicContact CG-CG2 4.34Å; Y133-V137 WeakPolarHBondContact O-CB 3.41Å; Y133-V137 VanDerWaalsContact O-CG2 3.27Å; Y133-V137 WeakPolarHBondContact O-CG2 3Å; Y133-V137 PolarHBondContact O-N 3.05Å; Y133-L184 HydrophobicContact CE1-CD2 4.29Å; Y133-L184 WeakPolarHBondContact OH-CD2 3.22Å; Y133-L184 PolarHBondContact OH-O 3.26Å; Y133-M187 HydrophobicContact CD2-CB 3.88Å; Y133-M187 WeakPolarHBondContact CD2-O 3.48Å; Y133-M187 HydrophobicContact CE2-CB 3.67Å; Y133-P191 HydrophobicContact CD2-CG 3.91Å; Y133-P191 HydrophobicContact CE2-CG 4.45Å; Y133-P191 HydrophobicContact CG-CG 4.2Å
134	L	95.3	Very high	94.6	Very high	33 Å²	33	29.1 Å²	29.1	17%	0.173	17%	0.168	C	C	.	.	H	α-helix	trans	-64.4	-30.9	-179.5	-67.7	-178.5	0	0	0	112	M103 F107 I130 V131 S138	M103-L134 HydrophobicContact SD-CD2 3.92Å; F107-L134 HydrophobicContact CB-CB 4.44Å; F107-L134 HydrophobicContact CB-CD1 3.89Å; F107-L134 HydrophobicContact CD1-CD1 3.95Å; F107-L134 HydrophobicContact CD2-CD1 4.12Å; F107-L134 HydrophobicContact CG-CD1 3.72Å; I130-L134 HydrophobicContact CG2-CD1 3.68Å; I130-L134 HydrophobicContact CG2-CG 4.14Å; I130-L134 WeakPolarHBondContact O-CB 3.39Å; I130-L134 WeakPolarHBondContact O-CG 3.46Å; I130-L134 PolarHBondContact O-N 3.02Å; V131-L134 PolarHBondContact O-N 2.93Å; L134-S138 VanDerWaalsContact O-CB 3.27Å; L134-S138 WeakPolarHBondContact O-CB 3.38Å; L134-S138 PolarHBondContact O-N 3.27Å; L134-S138 PolarHBondContact O-OG 2.88Å
135	M	93.6	Very high	94.7	Very high	37 Å²	37	27.8 Å²	27.8	18%	0.182	15%	0.153	C	C	.	.	H	α-helix	trans	-60.6	-57.6	171.1	-175.2	178.3	179.3	0	0	110.5	C108 V131 Y133 V137 S138 V139 Y380	C108-M135 HydrophobicContact CB-CB 4.23Å; C108-M135 HydrophobicContact CB-CG 4.34Å; C108-M135 WeakPolarHBondContact SG-CA 3.28Å; C108-M135 PolarHBondContact SG-N 3.26Å; V131-M135 VanDerWaalsContact O-CB 3.24Å; V131-M135 WeakPolarHBondContact O-CB 3.2Å; V131-M135 PolarHBondContact O-N 3.45Å; Y133-M135 PolarHBondContact O-N 3.3Å; M135-V137 VanDerWaalsContact C-N 3.32Å; M135-V137 PolarHBondContact O-N 3.28Å; M135-S138 PolarHBondContact O-N 3.43Å; M135-V139 VanDerWaalsContact O-CG2 3.26Å; M135-V139 WeakPolarHBondContact O-CG2 3.24Å; M135-V139 PolarHBondContact O-N 3.22Å; M135-Y380 HydrophobicContact CE-CE1 4.07Å; M135-Y380 WeakPolarHBondContact CE-OH 3.47Å
136	G	94	Very high	94.7	Very high	8 Å²	8	25.7 Å²	25.7	8%	0.082	14%	0.135	C	C	.	.	H	α-helix	trans	-58	-42	179	0	0	0	0	0	113.2	A132 Y133 V139 S140 M187	A132-G136 PolarHBondContact O-N 3.44Å; A132-G136 VanDerWaalsContact O-N 3.1Å; Y133-G136 PolarHBondContact O-N 2.95Å; G136-V139 PolarHBondContact O-N 3.32Å; G136-S140 WeakPolarHBondContact O-CB 3.4Å; G136-S140 PolarHBondContact O-N 3.23Å; G136-S140 PolarHBondContact O-OG 3.45Å; G136-M187 VanDerWaalsContact C-CG 3.47Å; G136-M187 WeakPolarHBondContact CA-SD 3.22Å
137	V	97.3	Very high	94.7	Very high	1 Å²	1	22 Å²	22	1%	0.006	11%	0.112	C	C	.	.	H	α-helix	trans	-64	-44.9	177.9	173.3	0	0	0	0	110.8	M103 Y133 M135 V139 S140 I141 L184 M187	M103-V137 HydrophobicContact CE-CB 4.26Å; M103-V137 HydrophobicContact CE-CG1 3.77Å; Y133-V137 HydrophobicContact CD1-CG2 4.33Å; Y133-V137 HydrophobicContact CD2-CG2 4.03Å; Y133-V137 HydrophobicContact CE1-CG2 4.03Å; Y133-V137 HydrophobicContact CE2-CG2 3.71Å; Y133-V137 HydrophobicContact CG-CG2 4.34Å; Y133-V137 WeakPolarHBondContact O-CB 3.41Å; Y133-V137 VanDerWaalsContact O-CG2 3.27Å; Y133-V137 WeakPolarHBondContact O-CG2 3Å; Y133-V137 PolarHBondContact O-N 3.05Å; M135-V137 VanDerWaalsContact C-N 3.32Å; M135-V137 PolarHBondContact O-N 3.28Å; V137-V139 PolarHBondContact O-N 3.13Å; V137-S140 PolarHBondContact O-N 3.3Å; V137-I141 HydrophobicContact CG1-CD1 3.58Å; V137-I141 HydrophobicContact CG1-CG1 4.24Å; V137-I141 VanDerWaalsContact O-CG1 3.3Å; V137-I141 WeakPolarHBondContact O-CG1 3.38Å; V137-I141 PolarHBondContact O-N 2.9Å; V137-L184 HydrophobicContact CG1-CD2 3.86Å; V137-L184 HydrophobicContact CG1-CG 4.41Å; V137-L184 HydrophobicContact CG2-CD2 4.1Å; V137-M187 HydrophobicContact CG2-CB 3.6Å; V137-M187 HydrophobicContact CG2-CG 3.87Å
138	S	96.1	Very high	94.8	Very high	0 Å²	0	19.4 Å²	19.4	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-60.2	-47.3	178.8	-58.4	0	0	0	0	111.4	M103 M104 L134 M135 S140 I141 S142	M103-S138 WeakPolarHBondContact CE-OG 3.4Å; M103-S138 WeakPolarHBondContact CG-OG 3.37Å; M104-S138 PolarHBondContact N-OG 3.41Å; L134-S138 VanDerWaalsContact O-CB 3.27Å; L134-S138 WeakPolarHBondContact O-CB 3.38Å; L134-S138 PolarHBondContact O-N 3.27Å; L134-S138 PolarHBondContact O-OG 2.88Å; M135-S138 PolarHBondContact O-N 3.43Å; S138-S140 VanDerWaalsContact C-N 3.3Å; S138-S140 PolarHBondContact O-N 3.48Å; S138-I141 PolarHBondContact O-N 3.32Å; S138-S142 WeakPolarHBondContact O-CB 3.29Å; S138-S142 PolarHBondContact O-N 3.27Å; S138-S142 PolarHBondContact O-OG 2.94Å
139	V	94.6	Very high	94.6	Very high	10 Å²	10	19.6 Å²	19.6	6%	0.061	10%	0.102	C	C	.	.	H	α-helix	trans	-57.8	-45.1	177.5	178	0	0	0	0	111	M104 M135 G136 V137 S142 T143 W346 Y350	M104-V139 HydrophobicContact CE-CB 4.33Å; M104-V139 HydrophobicContact CE-CG2 3.36Å; M135-V139 VanDerWaalsContact O-CG2 3.26Å; M135-V139 WeakPolarHBondContact O-CG2 3.24Å; M135-V139 PolarHBondContact O-N 3.22Å; G136-V139 PolarHBondContact O-N 3.32Å; V137-V139 PolarHBondContact O-N 3.13Å; V139-S142 PolarHBondContact O-N 3.12Å; V139-T143 WeakPolarHBondContact O-CB 3.45Å; V139-T143 PolarHBondContact O-N 2.88Å; V139-T143 PolarHBondContact O-OG1 3.36Å; V139-W346 HydrophobicContact CB-CH2 4.19Å; V139-W346 HydrophobicContact CB-CZ3 4.36Å; V139-W346 HydrophobicContact CG1-CE3 4.12Å; V139-W346 HydrophobicContact CG1-CH2 3.78Å; V139-W346 HydrophobicContact CG1-CZ2 4.25Å; V139-W346 HydrophobicContact CG1-CZ3 3.65Å; V139-W346 HydrophobicContact CG2-CH2 3.5Å; V139-W346 HydrophobicContact CG2-CZ2 4.44Å; V139-W346 HydrophobicContact CG2-CZ3 3.73Å; V139-Y350 WeakPolarHBondContact CG1-OH 3.13Å
140	S	96.8	Very high	94.5	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-66.4	-47.1	-177.9	-58	0	0	0	0	112.1	G136 V137 S138 S142 T143 F144 S183 M187	G136-S140 WeakPolarHBondContact O-CB 3.4Å; G136-S140 PolarHBondContact O-N 3.23Å; G136-S140 PolarHBondContact O-OG 3.45Å; V137-S140 PolarHBondContact O-N 3.3Å; S138-S140 VanDerWaalsContact C-N 3.3Å; S138-S140 PolarHBondContact O-N 3.48Å; S140-S142 VanDerWaalsContact C-N 3.35Å; S140-S142 PolarHBondContact O-N 2.84Å; S140-T143 PolarHBondContact O-N 3.47Å; S140-F144 VanDerWaalsContact O-CD2 3.28Å; S140-F144 WeakPolarHBondContact O-CD2 3.44Å; S140-F144 WeakPolarHBondContact O-CG 3.47Å; S140-F144 PolarHBondContact O-N 3.01Å; S140-S183 WeakPolarHBondContact CB-OG 3.47Å; S140-M187 WeakPolarHBondContact OG-CE 3.36Å
141	I	97.3	Very high	94.3	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-61.6	-45.8	178.1	-66	168	0	0	0	110	M103 V137 S138 T143 S145 W180 S183	M103-I141 HydrophobicContact CE-CD1 4.2Å; V137-I141 HydrophobicContact CG1-CD1 3.58Å; V137-I141 HydrophobicContact CG1-CG1 4.24Å; V137-I141 VanDerWaalsContact O-CG1 3.3Å; V137-I141 WeakPolarHBondContact O-CG1 3.38Å; V137-I141 PolarHBondContact O-N 2.9Å; S138-I141 PolarHBondContact O-N 3.32Å; I141-T143 VanDerWaalsContact C-N 3.34Å; I141-T143 PolarHBondContact O-N 3.42Å; I141-S145 WeakPolarHBondContact O-CB 3.29Å; I141-S145 PolarHBondContact O-N 3.17Å; I141-S145 PolarHBondContact O-OG 2.77Å; I141-W180 HydrophobicContact CD1-CD2 3.62Å; I141-W180 HydrophobicContact CD1-CE3 3.56Å; I141-W180 HydrophobicContact CD1-CG 4.19Å; I141-W180 HydrophobicContact CD1-CH2 4.02Å; I141-W180 HydrophobicContact CD1-CZ2 4.08Å; I141-W180 HydrophobicContact CD1-CZ3 3.77Å; I141-W180 HydrophobicContact CG1-CD2 4.4Å; I141-W180 HydrophobicContact CG2-CZ2 4.39Å; I141-S183 VanDerWaalsContact CG1-CB 3.49Å; I141-S183 WeakPolarHBondContact CG1-OG 3.22Å; I141-S183 PolarHBondContact N-OG 3.1Å
142	S	95.4	Very high	94.1	Very high	7 Å²	7	16.6 Å²	16.6	5%	0.049	9%	0.089	C	C	.	.	H	α-helix	trans	-60.9	-44.9	179	-67.9	0	0	0	0	110.9	S100 D101 S138 V139 S140 S145 L146	S100-S142 WeakPolarHBondContact CB-OG 3.22Å; S100-S142 PolarHBondContact OG-OG 3.35Å; D101-S142 PolarHBondContact OD1-OG 3.15Å; S138-S142 WeakPolarHBondContact O-CB 3.29Å; S138-S142 PolarHBondContact O-N 3.27Å; S138-S142 PolarHBondContact O-OG 2.94Å; V139-S142 PolarHBondContact O-N 3.12Å; S140-S142 VanDerWaalsContact C-N 3.35Å; S140-S142 PolarHBondContact O-N 2.84Å; S142-S145 PolarHBondContact O-N 3.39Å; S142-L146 WeakPolarHBondContact O-CG 3.39Å; S142-L146 PolarHBondContact O-N 3.02Å
143	T	95.3	Very high	93.9	Very high	2 Å²	2	18.4 Å²	18.4	1%	0.012	9%	0.092	C	C	.	.	H	α-helix	trans	-62	-53.1	178.6	-60.3	0	0	0	0	112.5	V139 S140 I141 S145 L146 V147 L231 P235 F342	V139-T143 WeakPolarHBondContact O-CB 3.45Å; V139-T143 PolarHBondContact O-N 2.88Å; V139-T143 PolarHBondContact O-OG1 3.36Å; S140-T143 PolarHBondContact O-N 3.47Å; I141-T143 VanDerWaalsContact C-N 3.34Å; I141-T143 PolarHBondContact O-N 3.42Å; T143-S145 VanDerWaalsContact C-N 3.25Å; T143-S145 PolarHBondContact O-N 3.32Å; T143-L146 WeakPolarHBondContact O-CB 3.26Å; T143-L146 PolarHBondContact O-N 2.7Å; T143-L146 VanDerWaalsContact O-N 3.15Å; T143-V147 PolarHBondContact O-N 3.22Å; T143-V147 VanDerWaalsContact O-N 3.12Å; T143-L231 VanDerWaalsContact CG2-O 3.3Å; T143-L231 WeakPolarHBondContact CG2-O 3.48Å; T143-P235 HydrophobicContact CG2-CB 3.57Å; T143-P235 HydrophobicContact CG2-CG 3.46Å; T143-P235 VanDerWaalsContact CG2-CG 3.46Å; T143-F342 HydrophobicContact CG2-CE2 3.95Å; T143-F342 HydrophobicContact CG2-CZ 4.05Å
144	F	96.1	Very high	93.6	Very high	34 Å²	34	19.1 Å²	19.1	15%	0.149	10%	0.095	C	C	.	.	H	α-helix	trans	-66.5	-30.1	179.3	-61.8	-38.6	0	0	0	112.2	S140 V147 A148 T179 V182 S183 I230 L231	S140-F144 VanDerWaalsContact O-CD2 3.28Å; S140-F144 WeakPolarHBondContact O-CD2 3.44Å; S140-F144 WeakPolarHBondContact O-CG 3.47Å; S140-F144 PolarHBondContact O-N 3.01Å; F144-V147 PolarHBondContact O-N 3.48Å; F144-A148 WeakPolarHBondContact O-CB 3.3Å; F144-A148 PolarHBondContact O-N 3.49Å; F144-T179 HydrophobicContact CB-CG2 3.76Å; F144-V182 HydrophobicContact CE2-CG1 3.9Å; F144-V182 HydrophobicContact CZ-CG1 4.37Å; F144-S183 WeakPolarHBondContact CD2-OG 3.24Å; F144-I230 HydrophobicContact CE1-CG2 4.26Å; F144-I230 HydrophobicContact CZ-CG2 3.86Å; F144-L231 HydrophobicContact CE1-CD2 4.11Å; F144-L231 HydrophobicContact CE2-CD2 4.21Å; F144-L231 HydrophobicContact CZ-CD2 3.69Å
145	S	94.6	Very high	93.2	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-65.9	-39.9	172.7	-61.8	0	0	0	0	111.7	I141 S142 T143 A148 I149	I141-S145 WeakPolarHBondContact O-CB 3.29Å; I141-S145 PolarHBondContact O-N 3.17Å; I141-S145 PolarHBondContact O-OG 2.77Å; S142-S145 PolarHBondContact O-N 3.39Å; T143-S145 VanDerWaalsContact C-N 3.25Å; T143-S145 PolarHBondContact O-N 3.32Å; S145-A148 PolarHBondContact O-N 2.97Å; S145-I149 WeakPolarHBondContact O-CB 3.41Å; S145-I149 WeakPolarHBondContact O-CD1 3.39Å; S145-I149 WeakPolarHBondContact O-CG1 3.39Å; S145-I149 PolarHBondContact O-N 3.34Å
146	L	92.6	Very high	92.7	Very high	12 Å²	12	18.9 Å²	18.9	6%	0.063	10%	0.102	C	C	.	.	H	α-helix	trans	-62.5	-42.6	174.3	-70.9	176	0	0	0	111.9	L97 S142 T143 I149 A150 M239 I338 F342	L97-L146 HydrophobicContact CD2-CD2 4.14Å; S142-L146 WeakPolarHBondContact O-CG 3.39Å; S142-L146 PolarHBondContact O-N 3.02Å; T143-L146 WeakPolarHBondContact O-CB 3.26Å; T143-L146 PolarHBondContact O-N 2.7Å; T143-L146 VanDerWaalsContact O-N 3.15Å; L146-I149 PolarHBondContact O-N 3.44Å; L146-A150 PolarHBondContact O-N 3.31Å; L146-M239 HydrophobicContact CB-SD 4.03Å; L146-I338 HydrophobicContact CD2-CG2 3.66Å; L146-F342 HydrophobicContact CD1-CD2 4.05Å
147	V	94.9	Very high	92.2	Very high	20 Å²	20	20.7 Å²	20.7	12%	0.121	11%	0.109	C	C	.	.	H	α-helix	trans	-61.6	-46.6	173.8	175	0	0	0	0	111.1	T143 F144 I149 A150 I151 P235 V238 M239	T143-V147 PolarHBondContact O-N 3.22Å; T143-V147 VanDerWaalsContact O-N 3.12Å; F144-V147 PolarHBondContact O-N 3.48Å; V147-I149 VanDerWaalsContact C-N 3.31Å; V147-I149 PolarHBondContact O-N 3.3Å; V147-A150 WeakPolarHBondContact O-CB 3.07Å; V147-A150 PolarHBondContact O-N 3.06Å; V147-A150 VanDerWaalsContact O-N 3.11Å; V147-I151 HydrophobicContact CG1-CD1 3.81Å; V147-I151 HydrophobicContact CG1-CG1 4.44Å; V147-I151 WeakPolarHBondContact O-CG1 3.25Å; V147-I151 PolarHBondContact O-N 3.14Å; V147-P235 HydrophobicContact CG2-CB 3.55Å; V147-P235 HydrophobicContact CG2-CG 4.35Å; V147-V238 HydrophobicContact CG1-CB 4.32Å; V147-V238 HydrophobicContact CG1-CG1 3.72Å; V147-M239 HydrophobicContact CG2-CG 4.32Å
148	A	93.4	Very high	91.6	Very high	12 Å²	12	21.8 Å²	21.8	10%	0.099	12%	0.116	C	C	.	.	H	α-helix	trans	-61.1	-40	177.7	0	0	0	0	0	111.9	F93 F144 S145 I151 E152 V175	F93-A148 HydrophobicContact CD1-CB 4.03Å; F93-A148 HydrophobicContact CE1-CB 3.7Å; F93-A148 HydrophobicContact CZ-CB 4.2Å; F144-A148 WeakPolarHBondContact O-CB 3.3Å; F144-A148 PolarHBondContact O-N 3.49Å; S145-A148 PolarHBondContact O-N 2.97Å; A148-I151 PolarHBondContact O-N 3.44Å; A148-E152 VanDerWaalsContact O-CB 3.3Å; A148-E152 WeakPolarHBondContact O-CB 3.4Å; A148-E152 PolarHBondContact O-N 2.96Å; A148-V175 HydrophobicContact CB-CG1 4Å
149	I	91.3	Very high	90.9	Very high	5 Å²	5	25.1 Å²	25.1	3%	0.026	13%	0.134	C	C	.	.	H	α-helix	trans	-62.1	-45.4	172.9	-68.4	162.7	0	0	0	110.1	F93 L94 L97 S145 L146 V147 I151 E152 R153 L335	F93-I149 HydrophobicContact CB-CD1 4.06Å; F93-I149 HydrophobicContact CB-CG1 3.56Å; F93-I149 HydrophobicContact CG-CG1 4.19Å; L94-I149 HydrophobicContact CD2-CD1 4.18Å; L97-I149 HydrophobicContact CD2-CD1 4.47Å; S145-I149 WeakPolarHBondContact O-CB 3.41Å; S145-I149 WeakPolarHBondContact O-CD1 3.39Å; S145-I149 WeakPolarHBondContact O-CG1 3.39Å; S145-I149 PolarHBondContact O-N 3.34Å; L146-I149 PolarHBondContact O-N 3.44Å; V147-I149 VanDerWaalsContact C-N 3.31Å; V147-I149 PolarHBondContact O-N 3.3Å; I149-I151 PolarHBondContact O-N 3.35Å; I149-E152 PolarHBondContact O-N 3.42Å; I149-R153 HydrophobicContact CG2-CG 4.33Å; I149-R153 WeakPolarHBondContact O-CB 3.2Å; I149-R153 VanDerWaalsContact O-CG 3.23Å; I149-R153 WeakPolarHBondContact O-CG 3.24Å; I149-R153 PolarHBondContact O-N 3.16Å; I149-L335 HydrophobicContact CG2-CD2 4.42Å
150	A	91.1	Very high	90.1	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-58.8	-46.1	178	0	0	0	0	0	112.2	L146 V147 R153 Y154 M239 A242 Y243	L146-A150 PolarHBondContact O-N 3.31Å; V147-A150 WeakPolarHBondContact O-CB 3.07Å; V147-A150 PolarHBondContact O-N 3.06Å; V147-A150 VanDerWaalsContact O-N 3.11Å; A150-R153 PolarHBondContact O-N 3.48Å; A150-Y154 WeakPolarHBondContact O-CB 3.25Å; A150-Y154 PolarHBondContact O-N 3.4Å; A150-M239 HydrophobicContact CB-CG 4.15Å; A150-A242 HydrophobicContact CB-CB 4.19Å; A150-Y243 WeakPolarHBondContact CA-OH 3.39Å; A150-Y243 HydrophobicContact CB-CD2 4.48Å; A150-Y243 HydrophobicContact CB-CE1 4.02Å; A150-Y243 HydrophobicContact CB-CE2 3.71Å; A150-Y243 VanDerWaalsContact CB-CZ 3.44Å; A150-Y243 WeakPolarHBondContact CB-OH 3.14Å
151	I	90.8	Very high	89.1	Confident	81 Å²	81	35.6 Å²	35.6	42%	0.415	19%	0.193	S	C	.	.	H	α-helix	trans	-66.9	-40.9	178.6	-65.4	169.5	0	0	0	111.4	V147 A148 I149 R153 Y154 S155 V238	V147-I151 HydrophobicContact CG1-CD1 3.81Å; V147-I151 HydrophobicContact CG1-CG1 4.44Å; V147-I151 WeakPolarHBondContact O-CG1 3.25Å; V147-I151 PolarHBondContact O-N 3.14Å; A148-I151 PolarHBondContact O-N 3.44Å; I149-I151 PolarHBondContact O-N 3.35Å; I151-R153 VanDerWaalsContact C-N 3.32Å; I151-R153 PolarHBondContact O-N 3.1Å; I151-Y154 PolarHBondContact O-N 3.42Å; I151-S155 WeakPolarHBondContact O-CB 3.36Å; I151-S155 PolarHBondContact O-N 2.93Å; I151-S155 PolarHBondContact O-OG 3.5Å; I151-V238 HydrophobicContact CD1-CG1 4.2Å; I151-V238 HydrophobicContact CG1-CG1 4.24Å
152	E	88.8	Confident	88.1	Confident	16 Å²	16	43.5 Å²	43.5	8%	0.075	23%	0.227	C	C	.	.	H	α-helix	trans	-58.3	-46.8	174.1	-179.2	-89	129.1	0	0	110.7	V89 T90 F93 A148 I149 S155 A156 Q167	V89-E152 HydrophobicContact CG1-CG 4.03Å; T90-E152 WeakPolarHBondContact CB-OE2 3.28Å; T90-E152 WeakPolarHBondContact CG2-OE2 3.4Å; T90-E152 PolarHBondContact OG1-OE1 3Å; T90-E152 PolarHBondContact OG1-OE2 3.36Å; F93-E152 HydrophobicContact CE2-CB 4.27Å; F93-E152 HydrophobicContact CE2-CG 4.28Å; A148-E152 VanDerWaalsContact O-CB 3.3Å; A148-E152 WeakPolarHBondContact O-CB 3.4Å; A148-E152 PolarHBondContact O-N 2.96Å; I149-E152 PolarHBondContact O-N 3.42Å; E152-S155 PolarHBondContact O-N 3.4Å; E152-A156 WeakPolarHBondContact O-CB 3.44Å; E152-A156 PolarHBondContact O-N 3.25Å; E152-Q167 PolarHBondContact O-NE2 2.99Å
153	R	88.1	Confident	87.1	Confident	54 Å²	54	43.8 Å²	43.8	20%	0.204	23%	0.229	C	C	.	.	H	α-helix	trans	-64.9	-43.3	178	-68.4	-52.1	-171.6	-152.4	4.8	112.7	T90 I149 A150 I151 A156 I157 I246 L335	T90-R153 VanDerWaalsContact OG1-CZ 3.28Å; T90-R153 PolarHBondContact OG1-NH1 2.89Å; T90-R153 PolarHBondContact OG1-NH2 3.34Å; I149-R153 HydrophobicContact CG2-CG 4.33Å; I149-R153 WeakPolarHBondContact O-CB 3.2Å; I149-R153 VanDerWaalsContact O-CG 3.23Å; I149-R153 WeakPolarHBondContact O-CG 3.24Å; I149-R153 PolarHBondContact O-N 3.16Å; A150-R153 PolarHBondContact O-N 3.48Å; I151-R153 VanDerWaalsContact C-N 3.32Å; I151-R153 PolarHBondContact O-N 3.1Å; R153-A156 PolarHBondContact O-N 3.4Å; R153-I157 WeakPolarHBondContact O-CB 3.33Å; R153-I157 VanDerWaalsContact O-CG1 3.29Å; R153-I157 WeakPolarHBondContact O-CG1 3.16Å; R153-I157 PolarHBondContact O-N 3.45Å; R153-I157 VanDerWaalsContact O-N 3.07Å; R153-I246 HydrophobicContact CB-CD1 4.06Å; R153-L335 HydrophobicContact CB-CD1 4.26Å; R153-L335 HydrophobicContact CG-CD1 3.92Å; R153-L335 HydrophobicContact CG-CD2 4.31Å
154	Y	88.3	Confident	86	Confident	70 Å²	70	54.3 Å²	54.3	28%	0.275	27%	0.269	S	S	.	.	H	α-helix	trans	-59.3	-49.8	176.8	167.4	-101.8	0	0	0	110.6	A150 I151 A156 I157 C158 L245 I246	A150-Y154 WeakPolarHBondContact O-CB 3.25Å; A150-Y154 PolarHBondContact O-N 3.4Å; I151-Y154 PolarHBondContact O-N 3.42Å; Y154-A156 PolarHBondContact O-N 2.97Å; Y154-I157 PolarHBondContact O-N 3.3Å; Y154-C158 HydrophobicContact CD2-CB 3.93Å; Y154-C158 VanDerWaalsContact CD2-SG 3.58Å; Y154-C158 HydrophobicContact CE2-CB 3.61Å; Y154-C158 WeakPolarHBondContact O-CB 3.22Å; Y154-C158 PolarHBondContact O-N 3.23Å; Y154-L245 HydrophobicContact CD2-CB 4.03Å; Y154-L245 HydrophobicContact CD2-CD1 4.34Å; Y154-L245 HydrophobicContact CE2-CB 3.75Å; Y154-L245 HydrophobicContact CE2-CD1 3.65Å; Y154-L245 HydrophobicContact CE2-CG 4.36Å; Y154-I246 HydrophobicContact CD2-CG1 4.26Å
155	S	86.9	Confident	84.8	Confident	33 Å²	33	56.7 Å²	56.7	23%	0.231	30%	0.295	C	S	.	.	H	α-helix	trans	-61.1	-44.5	-179.2	-57.4	0	0	0	0	111.7	I151 E152 I157 N159 S163	I151-S155 WeakPolarHBondContact O-CB 3.36Å; I151-S155 PolarHBondContact O-N 2.93Å; I151-S155 PolarHBondContact O-OG 3.5Å; E152-S155 PolarHBondContact O-N 3.4Å; S155-I157 VanDerWaalsContact C-N 3.34Å; S155-I157 PolarHBondContact O-N 2.85Å; S155-N159 CarbonylContact O-C 3.47Å; S155-N159 VanDerWaalsContact O-C 3.25Å; S155-N159 WeakPolarHBondContact O-CA 3.33Å; S155-N159 PolarHBondContact O-N 3.35Å; S155-N159 VanDerWaalsContact O-N 3.16Å; S155-S163 VanDerWaalsContact O-CB 3.26Å; S155-S163 WeakPolarHBondContact O-CB 3.4Å
156	A	83.8	Confident	83.6	Confident	32 Å²	32	65 Å²	65	26%	0.264	33%	0.326	S	S	.	.	H	α-helix	trans	-67.9	-29.7	-179.1	0	0	0	0	0	114.1	E152 R153 Y154	E152-A156 WeakPolarHBondContact O-CB 3.44Å; E152-A156 PolarHBondContact O-N 3.25Å; R153-A156 PolarHBondContact O-N 3.4Å; Y154-A156 PolarHBondContact O-N 2.97Å
157	I	83.4	Confident	82.7	Confident	46 Å²	46	66.7 Å²	66.7	24%	0.236	33%	0.334	C	S	.	.	H	α-helix	trans	-95.9	-49.5	-174.9	-63.6	169.5	0	0	0	111.3	R153 Y154 S155 I246	R153-I157 WeakPolarHBondContact O-CB 3.33Å; R153-I157 VanDerWaalsContact O-CG1 3.29Å; R153-I157 WeakPolarHBondContact O-CG1 3.16Å; R153-I157 PolarHBondContact O-N 3.45Å; R153-I157 VanDerWaalsContact O-N 3.07Å; Y154-I157 PolarHBondContact O-N 3.3Å; S155-I157 VanDerWaalsContact C-N 3.34Å; S155-I157 PolarHBondContact O-N 2.85Å; I157-I246 HydrophobicContact CD1-CG2 3.84Å; I157-I246 HydrophobicContact CG2-CG2 4.37Å
158	C	83.7	Confident	82.1	Confident	24 Å²	24	68.7 Å²	68.7	16%	0.162	35%	0.346	C	S	.	.	H	α-helix	trans	-82.8	-27.7	-174.3	-62	0	0	0	0	112.7	Y154	Y154-C158 HydrophobicContact CD2-CB 3.93Å; Y154-C158 VanDerWaalsContact CD2-SG 3.58Å; Y154-C158 HydrophobicContact CE2-CB 3.61Å; Y154-C158 WeakPolarHBondContact O-CB 3.22Å; Y154-C158 PolarHBondContact O-N 3.23Å
159	N	81.5	Confident	81.6	Confident	69 Å²	69	75.2 Å²	75.2	37%	0.369	37%	0.368	S	S	.	.			trans	-130.8	58	-177.1	-68.3	-49.3	0	0	0	112.7	S155 L161 K162 S163	S155-N159 CarbonylContact O-C 3.47Å; S155-N159 VanDerWaalsContact O-C 3.25Å; S155-N159 WeakPolarHBondContact O-CA 3.33Å; S155-N159 PolarHBondContact O-N 3.35Å; S155-N159 VanDerWaalsContact O-N 3.16Å; N159-L161 VanDerWaalsContact C-N 3.3Å; N159-L161 PolarHBondContact O-N 3.45Å; N159-L161 VanDerWaalsContact O-N 3.17Å; N159-K162 HydrophobicContact CB-CB 4.49Å; N159-K162 PolarHBondContact O-N 3.41Å; N159-S163 WeakPolarHBondContact O-CB 3.26Å; N159-S163 PolarHBondContact O-N 3.42Å; N159-S163 PolarHBondContact O-OG 2.69Å
160	P	77.3	Confident	81.4	Confident	77 Å²	77	78.6 Å²	78.6	50%	0.5	39%	0.392	S	S	.	.	H	α-helix	trans	-62.2	-29.9	-167.8	24.9	-35.4	0	0	0	114.8	S163 R164	P160-S163 WeakPolarHBondContact CA-OG 3.48Å; P160-S163 PolarHBondContact O-OG 2.9Å; P160-S163 VanDerWaalsContact O-OG 3.13Å; P160-R164 PolarHBondContact O-N 2.92Å
161	L	76.4	Confident	81.3	Confident	153 Å²	153	81.4 Å²	81.4	80%	0.801	41%	0.405	S	S	*	.	H	α-helix	trans	-77.2	-42.4	179.7	-65.1	175.6	0	0	0	112.1	N159	N159-L161 VanDerWaalsContact C-N 3.3Å; N159-L161 PolarHBondContact O-N 3.45Å; N159-L161 VanDerWaalsContact O-N 3.17Å
162	K	76.1	Confident	81.2	Confident	166 Å²	166	77.6 Å²	77.6	72%	0.722	39%	0.386	S	S	*	.	H	α-helix	trans	-70.7	-37.3	174.6	-71.3	-173.9	177.8	-179.1	0	111.4	N159 R164 A165 W166	N159-K162 HydrophobicContact CB-CB 4.49Å; N159-K162 PolarHBondContact O-N 3.41Å; K162-R164 VanDerWaalsContact C-N 3.28Å; K162-R164 PolarHBondContact O-N 3.2Å; K162-A165 PolarHBondContact O-N 3.39Å; K162-A165 VanDerWaalsContact O-N 3.15Å; K162-W166 PolarHBondContact O-N 3.32Å; K162-W166 VanDerWaalsContact O-N 3.09Å
163	S	75.1	Confident	81.4	Confident	13 Å²	13	83 Å²	83	9%	0.091	41%	0.406	C	S	.	.	H	α-helix	trans	-64.3	-32.8	179.6	80.7	0	0	0	0	112.3	S155 N159 P160 A165 W166 Q167	S155-S163 VanDerWaalsContact O-CB 3.26Å; S155-S163 WeakPolarHBondContact O-CB 3.4Å; N159-S163 WeakPolarHBondContact O-CB 3.26Å; N159-S163 PolarHBondContact O-N 3.42Å; N159-S163 PolarHBondContact O-OG 2.69Å; P160-S163 WeakPolarHBondContact CA-OG 3.48Å; P160-S163 PolarHBondContact O-OG 2.9Å; P160-S163 VanDerWaalsContact O-OG 3.13Å; S163-A165 PolarHBondContact O-N 3.21Å; S163-W166 PolarHBondContact O-N 3.27Å; S163-Q167 WeakPolarHBondContact O-CB 3.23Å; S163-Q167 WeakPolarHBondContact O-CG 3.43Å; S163-Q167 PolarHBondContact O-N 2.66Å
164	R	72.8	Confident	81.6	Confident	224 Å²	224	89.4 Å²	89.4	85%	0.845	43%	0.43	S	S	*	.	H	α-helix	trans	-62.3	-31.6	175.9	-162.3	176.5	85.5	169.1	4.9	112.9	P160 K162	P160-R164 PolarHBondContact O-N 2.92Å; K162-R164 VanDerWaalsContact C-N 3.28Å; K162-R164 PolarHBondContact O-N 3.2Å
165	A	69.6	Low	81.9	Confident	83 Å²	83	88 Å²	88	69%	0.686	43%	0.429	S	S	*	.	H	α-helix	trans	-83.2	-35.5	176.2	0	0	0	0	0	112.5	K162 S163	K162-A165 PolarHBondContact O-N 3.39Å; K162-A165 VanDerWaalsContact O-N 3.15Å; S163-A165 PolarHBondContact O-N 3.21Å
166	W	68.9	Low	82.4	Confident	174 Å²	174	87.3 Å²	87.3	66%	0.659	42%	0.423	S	S	*	.	H	α-helix	trans	-91.4	-32.7	-173.2	-166.3	-82.7	0	0	0	114.8	K162 S163 T168 H171	K162-W166 PolarHBondContact O-N 3.32Å; K162-W166 VanDerWaalsContact O-N 3.09Å; S163-W166 PolarHBondContact O-N 3.27Å; W166-T168 VanDerWaalsContact C-N 3.28Å; W166-T168 PolarHBondContact O-N 2.87Å; W166-H171 AromaticContact CD1-NE2 3.93Å; W166-H171 AromaticContact CE2-NE2 3.8Å; W166-H171 AromaticContact NE1-CD2 3.51Å; W166-H171 AromaticContact NE1-CE1 3.49Å; W166-H171 PolarHBondContact NE1-CE1 2.83Å; W166-H171 AromaticContact NE1-NE2 3.04Å; W166-H171 PolarHBondContact NE1-NE2 2.96Å
167	Q	73.7	Confident	83	Confident	48 Å²	48	88.4 Å²	88.4	22%	0.224	43%	0.432	C	S	.	.			trans	-83.4	64	-174.8	-69	-176.5	-32.9	0	0	112.9	E152 S163	E152-Q167 PolarHBondContact O-NE2 2.99Å; S163-Q167 WeakPolarHBondContact O-CB 3.23Å; S163-Q167 WeakPolarHBondContact O-CG 3.43Å; S163-Q167 PolarHBondContact O-N 2.66Å
168	T	83.7	Confident	83.6	Confident	63 Å²	63	88.7 Å²	88.7	39%	0.387	44%	0.441	S	S	.	.			trans	-82.8	156.7	171.4	62.3	0	0	0	0	111.2	W166 S170 H171 A172	W166-T168 VanDerWaalsContact C-N 3.28Å; W166-T168 PolarHBondContact O-N 2.87Å; T168-S170 VanDerWaalsContact C-N 3.27Å; T168-S170 PolarHBondContact O-N 3.05Å; T168-S170 PolarHBondContact OG1-OG 2.9Å; T168-S170 VanDerWaalsContact OG1-OG 3.05Å; T168-H171 PolarHBondContact O-N 2.93Å; T168-H171 WeakPolarHBondContact OG1-CB 3.3Å; T168-H171 PolarHBondContact OG1-N 3.23Å; T168-A172 PolarHBondContact O-N 2.94Å; T168-A172 VanDerWaalsContact O-N 3.13Å
169	R	81.7	Confident	84.2	Confident	149 Å²	149	88.2 Å²	88.2	56%	0.562	44%	0.437	S	S	*	.	H	α-helix	trans	-62.3	-35.5	174.3	-69.1	-171.1	-178.4	112.5	-2.4	112	R87 V89 A172 Y173	R87-R169 PolarHBondContact O-NE 3.16Å; R87-R169 PolarHBondContact O-NH2 2.88Å; V89-R169 HydrophobicContact CG2-CG 4.39Å; R169-A172 WeakPolarHBondContact O-CB 3.46Å; R169-A172 PolarHBondContact O-N 3.46Å; R169-Y173 HydrophobicContact CB-CE2 4.36Å; R169-Y173 WeakPolarHBondContact O-CD2 3.41Å; R169-Y173 PolarHBondContact O-N 3.34Å
170	S	87.4	Confident	85	Confident	76 Å²	76	88.5 Å²	88.5	53%	0.531	43%	0.433	S	S	.	.	H	α-helix	trans	-64.2	-42.8	176.7	49.6	0	0	0	0	111.7	T168 A172 Y173 R174	T168-S170 VanDerWaalsContact C-N 3.27Å; T168-S170 PolarHBondContact O-N 3.05Å; T168-S170 PolarHBondContact OG1-OG 2.9Å; T168-S170 VanDerWaalsContact OG1-OG 3.05Å; S170-A172 VanDerWaalsContact C-N 3.32Å; S170-A172 PolarHBondContact O-N 2.96Å; S170-Y173 PolarHBondContact O-N 3.02Å; S170-R174 WeakPolarHBondContact O-CG 3.47Å; S170-R174 PolarHBondContact O-N 2.91Å
171	H	88.4	Confident	86	Confident	59 Å²	59	88.7 Å²	88.7	27%	0.273	43%	0.433	S	S	.	.	H	α-helix	trans	-59.2	-44.6	172.8	-177.1	-82.7	0	0	0	111.3	W166 T168 Y173 R174 V175	W166-H171 AromaticContact CD1-NE2 3.93Å; W166-H171 AromaticContact CE2-NE2 3.8Å; W166-H171 AromaticContact NE1-CD2 3.51Å; W166-H171 AromaticContact NE1-CE1 3.49Å; W166-H171 PolarHBondContact NE1-CE1 2.83Å; W166-H171 AromaticContact NE1-NE2 3.04Å; W166-H171 PolarHBondContact NE1-NE2 2.96Å; T168-H171 PolarHBondContact O-N 2.93Å; T168-H171 WeakPolarHBondContact OG1-CB 3.3Å; T168-H171 PolarHBondContact OG1-N 3.23Å; H171-Y173 PolarHBondContact O-N 2.93Å; H171-R174 PolarHBondContact O-N 3.07Å; H171-V175 VanDerWaalsContact CE1-CG2 3.46Å; H171-V175 WeakPolarHBondContact CE1-CG2 3.5Å; H171-V175 WeakPolarHBondContact O-CG2 3.15Å; H171-V175 PolarHBondContact O-N 3.48Å
172	A	89.9	Confident	87	Confident	0 Å²	0	84.6 Å²	84.6	0%	0	41%	0.414	C	S	.	.	H	α-helix	trans	-57.3	-48.4	177.1	0	0	0	0	0	112.5	V89 F93 T168 R169 S170 R174 V175 I176	V89-A172 HydrophobicContact CB-CB 4.39Å; V89-A172 HydrophobicContact CG1-CB 3.75Å; V89-A172 HydrophobicContact CG2-CB 4.43Å; F93-A172 HydrophobicContact CE2-CB 4.32Å; F93-A172 HydrophobicContact CZ-CB 4.32Å; T168-A172 PolarHBondContact O-N 2.94Å; T168-A172 VanDerWaalsContact O-N 3.13Å; R169-A172 WeakPolarHBondContact O-CB 3.46Å; R169-A172 PolarHBondContact O-N 3.46Å; S170-A172 VanDerWaalsContact C-N 3.32Å; S170-A172 PolarHBondContact O-N 2.96Å; A172-R174 VanDerWaalsContact C-N 3.33Å; A172-R174 PolarHBondContact O-N 3.28Å; A172-V175 PolarHBondContact O-N 3.45Å; A172-I176 WeakPolarHBondContact O-CG1 3.48Å; A172-I176 PolarHBondContact O-N 2.67Å
173	Y	92.4	Very high	88	Confident	130 Å²	130	76.7 Å²	76.7	51%	0.51	38%	0.38	S	S	.	.	H	α-helix	trans	-64.9	-35.5	177.8	-71.9	-58.9	0	0	0	112.8	R169 S170 H171 I176 A177	R169-Y173 HydrophobicContact CB-CE2 4.36Å; R169-Y173 WeakPolarHBondContact O-CD2 3.41Å; R169-Y173 PolarHBondContact O-N 3.34Å; S170-Y173 PolarHBondContact O-N 3.02Å; H171-Y173 PolarHBondContact O-N 2.93Å; Y173-I176 HydrophobicContact CD1-CD1 4.5Å; Y173-I176 PolarHBondContact O-N 2.94Å; Y173-A177 WeakPolarHBondContact O-CB 3.43Å; Y173-A177 PolarHBondContact O-N 3.35Å
174	R	93.6	Very high	89.1	Confident	188 Å²	188	79.1 Å²	79.1	71%	0.709	39%	0.391	S	S	*	.	H	α-helix	trans	-63.5	-43	173.1	-74.9	176.3	62.3	-165.5	-1.7	112	S170 H171 A172 A177 A178	S170-R174 WeakPolarHBondContact O-CG 3.47Å; S170-R174 PolarHBondContact O-N 2.91Å; H171-R174 PolarHBondContact O-N 3.07Å; A172-R174 VanDerWaalsContact C-N 3.33Å; A172-R174 PolarHBondContact O-N 3.28Å; R174-A177 PolarHBondContact O-N 3.46Å; R174-A178 WeakPolarHBondContact O-CB 3.39Å; R174-A178 PolarHBondContact O-N 3.42Å
175	V	94.4	Very high	90.2	Very high	40 Å²	40	74 Å²	74	24%	0.242	38%	0.38	C	S	.	.	H	α-helix	trans	-62.3	-46.2	175.5	175	0	0	0	0	110.2	F93 A148 H171 A172 A177 A178 T179	F93-V175 HydrophobicContact CE1-CB 4.17Å; F93-V175 HydrophobicContact CE1-CG1 3.83Å; F93-V175 HydrophobicContact CZ-CB 4.2Å; F93-V175 HydrophobicContact CZ-CG1 4.09Å; A148-V175 HydrophobicContact CB-CG1 4Å; H171-V175 VanDerWaalsContact CE1-CG2 3.46Å; H171-V175 WeakPolarHBondContact CE1-CG2 3.5Å; H171-V175 WeakPolarHBondContact O-CG2 3.15Å; H171-V175 PolarHBondContact O-N 3.48Å; A172-V175 PolarHBondContact O-N 3.45Å; V175-A177 PolarHBondContact O-N 2.95Å; V175-A178 PolarHBondContact O-N 3.4Å; V175-T179 HydrophobicContact CG1-CG2 4.42Å; V175-T179 WeakPolarHBondContact O-CG2 3.45Å; V175-T179 PolarHBondContact O-N 3.06Å
176	I	95.9	Very high	91.5	Very high	20 Å²	20	71.7 Å²	71.7	10%	0.103	36%	0.357	C	S	.	.	H	α-helix	trans	-59.9	-48.4	176.5	-65.8	166.2	0	0	0	110.6	F93 A172 Y173 A178 T179 W180	F93-I176 HydrophobicContact CD1-CD1 4.03Å; F93-I176 HydrophobicContact CD1-CG1 3.65Å; F93-I176 HydrophobicContact CE1-CD1 4.26Å; F93-I176 HydrophobicContact CE1-CG1 3.65Å; A172-I176 WeakPolarHBondContact O-CG1 3.48Å; A172-I176 PolarHBondContact O-N 2.67Å; Y173-I176 HydrophobicContact CD1-CD1 4.5Å; Y173-I176 PolarHBondContact O-N 2.94Å; I176-A178 VanDerWaalsContact C-N 3.27Å; I176-A178 PolarHBondContact O-N 3.05Å; I176-T179 PolarHBondContact O-N 2.94Å; I176-T179 VanDerWaalsContact O-N 3.16Å; I176-T179 PolarHBondContact O-OG1 3.49Å; I176-W180 PolarHBondContact O-N 2.88Å
177	A	96.8	Very high	92.8	Very high	55 Å²	55	63.5 Å²	63.5	46%	0.455	33%	0.326	S	S	.	.	H	α-helix	trans	-58.2	-42	177.7	0	0	0	0	0	111.7	Y173 R174 V175 W180 V181	Y173-A177 WeakPolarHBondContact O-CB 3.43Å; Y173-A177 PolarHBondContact O-N 3.35Å; R174-A177 PolarHBondContact O-N 3.46Å; V175-A177 PolarHBondContact O-N 2.95Å; A177-W180 PolarHBondContact O-N 3.23Å; A177-V181 VanDerWaalsContact O-CG2 3.32Å; A177-V181 WeakPolarHBondContact O-CG2 3.35Å; A177-V181 PolarHBondContact O-N 3.03Å
178	A	96.6	Very high	93.8	Very high	52 Å²	52	64.4 Å²	64.4	43%	0.43	34%	0.335	S	S	.	.	H	α-helix	trans	-63.5	-42.7	175.9	0	0	0	0	0	112.5	R174 V175 I176 W180 V181 V182	R174-A178 WeakPolarHBondContact O-CB 3.39Å; R174-A178 PolarHBondContact O-N 3.42Å; V175-A178 PolarHBondContact O-N 3.4Å; I176-A178 VanDerWaalsContact C-N 3.27Å; I176-A178 PolarHBondContact O-N 3.05Å; A178-W180 VanDerWaalsContact C-N 3.3Å; A178-W180 PolarHBondContact O-N 3.22Å; A178-V181 PolarHBondContact O-N 3.34Å; A178-V182 WeakPolarHBondContact O-CB 3.35Å; A178-V182 VanDerWaalsContact O-CG2 3.29Å; A178-V182 WeakPolarHBondContact O-CG2 3.28Å; A178-V182 PolarHBondContact O-N 3.22Å
179	T	96.6	Very high	94.3	Very high	14 Å²	14	62.8 Å²	62.8	9%	0.086	33%	0.326	C	S	.	.	H	α-helix	trans	-63	-38.4	177.9	59.1	0	0	0	0	111.8	F144 V175 I176 S183	F144-T179 HydrophobicContact CB-CG2 3.76Å; V175-T179 HydrophobicContact CG1-CG2 4.42Å; V175-T179 WeakPolarHBondContact O-CG2 3.45Å; V175-T179 PolarHBondContact O-N 3.06Å; I176-T179 PolarHBondContact O-N 2.94Å; I176-T179 VanDerWaalsContact O-N 3.16Å; I176-T179 PolarHBondContact O-OG1 3.49Å; T179-S183 VanDerWaalsContact O-CB 3.25Å; T179-S183 WeakPolarHBondContact O-CB 3.37Å; T179-S183 PolarHBondContact O-N 3.46Å; T179-S183 PolarHBondContact O-OG 3.35Å
180	W	97.9	Very high	94.9	Very high	75 Å²	75	57.3 Å²	57.3	28%	0.284	31%	0.305	S	S	.	.	H	α-helix	trans	-65.5	-49.8	175	-81	69.2	0	0	0	111.9	S96 V99 I141 I176 A177 A178 V182 S183 L184	S96-W180 PolarHBondContact OG-NE1 3.46Å; S96-W180 VanDerWaalsContact OG-NE1 3.08Å; V99-W180 HydrophobicContact CB-CZ2 4.38Å; V99-W180 HydrophobicContact CG1-CH2 3.73Å; V99-W180 HydrophobicContact CG1-CZ2 3.81Å; I141-W180 HydrophobicContact CD1-CD2 3.62Å; I141-W180 HydrophobicContact CD1-CE3 3.56Å; I141-W180 HydrophobicContact CD1-CG 4.19Å; I141-W180 HydrophobicContact CD1-CH2 4.02Å; I141-W180 HydrophobicContact CD1-CZ2 4.08Å; I141-W180 HydrophobicContact CD1-CZ3 3.77Å; I141-W180 HydrophobicContact CG1-CD2 4.4Å; I141-W180 HydrophobicContact CG2-CZ2 4.39Å; I176-W180 PolarHBondContact O-N 2.88Å; A177-W180 PolarHBondContact O-N 3.23Å; A178-W180 VanDerWaalsContact C-N 3.3Å; A178-W180 PolarHBondContact O-N 3.22Å; W180-V182 PolarHBondContact O-N 2.87Å; W180-S183 PolarHBondContact O-N 3.28Å; W180-L184 WeakPolarHBondContact O-CB 2.92Å; W180-L184 VanDerWaalsContact O-CG 3.24Å; W180-L184 WeakPolarHBondContact O-CG 3.27Å; W180-L184 PolarHBondContact O-N 3.12Å
181	V	98	Very high	95.2	Very high	80 Å²	80	55.5 Å²	55.5	49%	0.485	29%	0.292	S	S	.	.	H	α-helix	trans	-59.5	-49.1	179.1	170.1	0	0	0	0	110.9	A177 A178 S183 L184 L185	A177-V181 VanDerWaalsContact O-CG2 3.32Å; A177-V181 WeakPolarHBondContact O-CG2 3.35Å; A177-V181 PolarHBondContact O-N 3.03Å; A178-V181 PolarHBondContact O-N 3.34Å; V181-S183 VanDerWaalsContact C-N 3.32Å; V181-S183 PolarHBondContact O-N 3.37Å; V181-L184 PolarHBondContact O-N 2.87Å; V181-L185 HydrophobicContact CG1-CD1 3.8Å; V181-L185 HydrophobicContact CG1-CG 4.37Å; V181-L185 WeakPolarHBondContact O-CB 3.35Å; V181-L185 VanDerWaalsContact O-CG 3.27Å; V181-L185 WeakPolarHBondContact O-CG 3.33Å; V181-L185 PolarHBondContact O-N 2.73Å
182	V	96.9	Very high	95.5	Very high	68 Å²	68	56.7 Å²	56.7	41%	0.412	30%	0.303	S	S	.	.	H	α-helix	trans	-60.9	-42.8	178.2	172.5	0	0	0	0	111	F144 A178 W180 L184 L185 V186	F144-V182 HydrophobicContact CE2-CG1 3.9Å; F144-V182 HydrophobicContact CZ-CG1 4.37Å; A178-V182 WeakPolarHBondContact O-CB 3.35Å; A178-V182 VanDerWaalsContact O-CG2 3.29Å; A178-V182 WeakPolarHBondContact O-CG2 3.28Å; A178-V182 PolarHBondContact O-N 3.22Å; W180-V182 PolarHBondContact O-N 2.87Å; V182-L184 PolarHBondContact O-N 3.24Å; V182-L185 PolarHBondContact O-N 3Å; V182-V186 HydrophobicContact CG1-CG2 4.03Å; V182-V186 WeakPolarHBondContact O-CB 3.33Å; V182-V186 VanDerWaalsContact O-CG2 3.25Å; V182-V186 WeakPolarHBondContact O-CG2 2.88Å; V182-V186 PolarHBondContact O-N 2.79Å
183	S	97.9	Very high	95.8	Very high	0 Å²	0	59.5 Å²	59.5	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-63.9	-41.6	178.7	-60.9	0	0	0	0	112.6	S140 I141 F144 T179 W180 V181 M187	S140-S183 WeakPolarHBondContact CB-OG 3.47Å; I141-S183 VanDerWaalsContact CG1-CB 3.49Å; I141-S183 WeakPolarHBondContact CG1-OG 3.22Å; I141-S183 PolarHBondContact N-OG 3.1Å; F144-S183 WeakPolarHBondContact CD2-OG 3.24Å; T179-S183 VanDerWaalsContact O-CB 3.25Å; T179-S183 WeakPolarHBondContact O-CB 3.37Å; T179-S183 PolarHBondContact O-N 3.46Å; T179-S183 PolarHBondContact O-OG 3.35Å; W180-S183 PolarHBondContact O-N 3.28Å; V181-S183 VanDerWaalsContact C-N 3.32Å; V181-S183 PolarHBondContact O-N 3.37Å; S183-M187 WeakPolarHBondContact O-CB 3.39Å; S183-M187 WeakPolarHBondContact O-CG 3.38Å; S183-M187 PolarHBondContact O-N 2.98Å
184	L	97.3	Very high	95.8	Very high	64 Å²	64	53.5 Å²	53.5	34%	0.335	29%	0.292	S	S	.	.	H	α-helix	trans	-63.3	-45	176.2	-70	165.6	0	0	0	110.7	Y133 V137 W180 V181 V182 M187 V188	Y133-L184 HydrophobicContact CE1-CD2 4.29Å; Y133-L184 WeakPolarHBondContact OH-CD2 3.22Å; Y133-L184 PolarHBondContact OH-O 3.26Å; V137-L184 HydrophobicContact CG1-CD2 3.86Å; V137-L184 HydrophobicContact CG1-CG 4.41Å; V137-L184 HydrophobicContact CG2-CD2 4.1Å; W180-L184 WeakPolarHBondContact O-CB 2.92Å; W180-L184 VanDerWaalsContact O-CG 3.24Å; W180-L184 WeakPolarHBondContact O-CG 3.27Å; W180-L184 PolarHBondContact O-N 3.12Å; V181-L184 PolarHBondContact O-N 2.87Å; V182-L184 PolarHBondContact O-N 3.24Å; L184-M187 PolarHBondContact O-N 3.42Å; L184-V188 WeakPolarHBondContact O-CG2 3.49Å
185	L	96.9	Very high	95.8	Very high	116 Å²	116	47.3 Å²	47.3	61%	0.607	28%	0.275	S	S	*	.	H	α-helix	trans	-66.7	-47.4	-179.9	-70.4	174.1	0	0	0	112.8	V181 V182 M187 V188	V181-L185 HydrophobicContact CG1-CD1 3.8Å; V181-L185 HydrophobicContact CG1-CG 4.37Å; V181-L185 WeakPolarHBondContact O-CB 3.35Å; V181-L185 VanDerWaalsContact O-CG 3.27Å; V181-L185 WeakPolarHBondContact O-CG 3.33Å; V181-L185 PolarHBondContact O-N 2.73Å; V182-L185 PolarHBondContact O-N 3Å; L185-M187 PolarHBondContact O-N 3.44Å; L185-V188 WeakPolarHBondContact O-CB 3.43Å; L185-V188 VanDerWaalsContact O-CG2 3.32Å; L185-V188 WeakPolarHBondContact O-CG2 3.42Å; L185-V188 PolarHBondContact O-N 3.45Å
186	V	95.6	Very high	95.9	Very high	35 Å²	35	47.5 Å²	47.5	21%	0.212	28%	0.275	C	S	.	.	H	α-helix	trans	-59.3	-33.6	179.6	170.1	0	0	0	0	110.2	V182 P189 W223 L227	V182-V186 HydrophobicContact CG1-CG2 4.03Å; V182-V186 WeakPolarHBondContact O-CB 3.33Å; V182-V186 VanDerWaalsContact O-CG2 3.25Å; V182-V186 WeakPolarHBondContact O-CG2 2.88Å; V182-V186 PolarHBondContact O-N 2.79Å; V186-P189 WeakPolarHBondContact O-CD 3.41Å; V186-W223 VanDerWaalsContact O-CH2 3.24Å; V186-W223 WeakPolarHBondContact O-CH2 3.49Å; V186-L227 HydrophobicContact CG1-CD2 4.4Å
187	M	96.2	Very high	95.7	Very high	1 Å²	1	49.4 Å²	49.4	1%	0.005	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.1	-0.9	-173.6	-64.7	-66.5	143.9	0	0	115.2	Y133 G136 V137 S140 S183 L184 L185 P189 Y190 L227 L231	Y133-M187 HydrophobicContact CD2-CB 3.88Å; Y133-M187 WeakPolarHBondContact CD2-O 3.48Å; Y133-M187 HydrophobicContact CE2-CB 3.67Å; G136-M187 VanDerWaalsContact C-CG 3.47Å; G136-M187 WeakPolarHBondContact CA-SD 3.22Å; V137-M187 HydrophobicContact CG2-CB 3.6Å; V137-M187 HydrophobicContact CG2-CG 3.87Å; S140-M187 WeakPolarHBondContact OG-CE 3.36Å; S183-M187 WeakPolarHBondContact O-CB 3.39Å; S183-M187 WeakPolarHBondContact O-CG 3.38Å; S183-M187 PolarHBondContact O-N 2.98Å; L184-M187 PolarHBondContact O-N 3.42Å; L185-M187 PolarHBondContact O-N 3.44Å; M187-P189 VanDerWaalsContact C-N 3.29Å; M187-P189 VanDerWaalsContact O-N 3.17Å; M187-Y190 HydrophobicContact CB-CD2 4.34Å; M187-Y190 WeakPolarHBondContact O-CB 3.47Å; M187-Y190 PolarHBondContact O-N 2.69Å; M187-Y190 VanDerWaalsContact O-N 3.08Å; M187-Y190 HydrophobicContact SD-CD2 3.63Å; M187-Y190 HydrophobicContact SD-CE2 3.39Å; M187-Y190 WeakPolarHBondContact SD-CE2 3.23Å; M187-L227 HydrophobicContact CE-CD2 3.66Å; M187-L231 HydrophobicContact CE-CD1 3.53Å
188	V	95.8	Very high	95.5	Very high	67 Å²	67	50.7 Å²	50.7	41%	0.406	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.1	-34.5	-178.9	170	0	0	0	0	114.7	L184 L185 Y190 P191	L184-V188 WeakPolarHBondContact O-CG2 3.49Å; L185-V188 WeakPolarHBondContact O-CB 3.43Å; L185-V188 VanDerWaalsContact O-CG2 3.32Å; L185-V188 WeakPolarHBondContact O-CG2 3.42Å; L185-V188 PolarHBondContact O-N 3.45Å; V188-Y190 VanDerWaalsContact C-N 3.25Å; V188-Y190 PolarHBondContact O-N 2.98Å; V188-P191 WeakPolarHBondContact O-CD 3.17Å; V188-P191 VanDerWaalsContact O-CG 3.24Å; V188-P191 WeakPolarHBondContact O-CG 3.44Å
189	P	95	Very high	95.1	Very high	29 Å²	29	51.9 Å²	51.9	19%	0.188	28%	0.284	C	S	.	.	H	α-helix	trans	-62.7	-26.9	178.2	-30.8	41.7	0	0	0	114.7	V186 M187 V192 F193 W214 W223	V186-P189 WeakPolarHBondContact O-CD 3.41Å; M187-P189 VanDerWaalsContact C-N 3.29Å; M187-P189 VanDerWaalsContact O-N 3.17Å; P189-V192 PolarHBondContact O-N 2.96Å; P189-F193 HydrophobicContact CB-CD2 3.93Å; P189-F193 HydrophobicContact CB-CE2 4.09Å; P189-F193 VanDerWaalsContact O-CD2 3.24Å; P189-F193 WeakPolarHBondContact O-CD2 3.49Å; P189-F193 PolarHBondContact O-N 3.08Å; P189-W214 HydrophobicContact CB-CH2 3.82Å; P189-W214 HydrophobicContact CB-CZ3 4.46Å; P189-W223 HydrophobicContact CB-CE3 4.41Å; P189-W223 HydrophobicContact CB-CH2 3.73Å; P189-W223 HydrophobicContact CB-CZ2 4.03Å; P189-W223 HydrophobicContact CB-CZ3 3.96Å; P189-W223 HydrophobicContact CG-CE3 4.3Å; P189-W223 HydrophobicContact CG-CH2 3.48Å; P189-W223 VanDerWaalsContact CG-CH2 3.48Å; P189-W223 HydrophobicContact CG-CZ2 4.28Å; P189-W223 HydrophobicContact CG-CZ3 3.51Å
190	Y	93.4	Very high	94.7	Very high	34 Å²	34	56.7 Å²	56.7	13%	0.133	32%	0.315	C	S	.	.	H	α-helix	trans	-56.8	-54.7	179.3	-81.4	-81.4	0	0	0	113.7	A132 M187 V188 V192 N194 L212 W223 L227	A132-Y190 HydrophobicContact CB-CD1 4.16Å; M187-Y190 HydrophobicContact CB-CD2 4.34Å; M187-Y190 WeakPolarHBondContact O-CB 3.47Å; M187-Y190 PolarHBondContact O-N 2.69Å; M187-Y190 VanDerWaalsContact O-N 3.08Å; M187-Y190 HydrophobicContact SD-CD2 3.63Å; M187-Y190 HydrophobicContact SD-CE2 3.39Å; M187-Y190 WeakPolarHBondContact SD-CE2 3.23Å; V188-Y190 VanDerWaalsContact C-N 3.25Å; V188-Y190 PolarHBondContact O-N 2.98Å; Y190-V192 PolarHBondContact O-N 3.32Å; Y190-N194 WeakPolarHBondContact O-CB 2.92Å; Y190-N194 PolarHBondContact O-N 3.27Å; Y190-N194 PolarHBondContact O-ND2 2.87Å; Y190-L212 HydrophobicContact CD1-CD1 4.16Å; Y190-L212 HydrophobicContact CD1-CD2 4.13Å; Y190-L212 HydrophobicContact CE1-CD1 4.08Å; Y190-L212 HydrophobicContact CE1-CD2 4.01Å; Y190-W223 AromaticContact CD2-CZ2 3.9Å; Y190-W223 HydrophobicContact CD2-CZ2 3.9Å; Y190-W223 AromaticContact CE2-CZ2 3.6Å; Y190-W223 HydrophobicContact CE2-CZ2 3.6Å; Y190-L227 HydrophobicContact CE2-CD1 4.3Å; Y190-L227 WeakPolarHBondContact OH-CD1 3.42Å
191	P	94.6	Very high	94.1	Very high	38 Å²	38	55.8 Å²	55.8	25%	0.247	31%	0.313	C	S	.	.	H	α-helix	trans	-69.5	-18.3	179.1	25.9	-36.4	0	0	0	114.1	K129 Y133 V188	K129-P191 HydrophobicContact CB-CB 4.27Å; K129-P191 VanDerWaalsContact CD-O 3.28Å; K129-P191 WeakPolarHBondContact CD-O 3.42Å; K129-P191 WeakPolarHBondContact CE-O 3.32Å; K129-P191 PolarHBondContact NZ-O 3Å; K129-P191 VanDerWaalsContact NZ-O 3.11Å; Y133-P191 HydrophobicContact CD2-CG 3.91Å; Y133-P191 HydrophobicContact CE2-CG 4.45Å; Y133-P191 HydrophobicContact CG-CG 4.2Å; V188-P191 WeakPolarHBondContact O-CD 3.17Å; V188-P191 VanDerWaalsContact O-CG 3.24Å; V188-P191 WeakPolarHBondContact O-CG 3.44Å
192	V	94.7	Very high	93.2	Very high	85 Å²	85	56 Å²	56	52%	0.515	33%	0.331	S	S	.	.	H	α-helix	trans	-76.3	-50.2	176	178.6	0	0	0	0	110.3	P189 Y190	P189-V192 PolarHBondContact O-N 2.96Å; Y190-V192 PolarHBondContact O-N 3.32Å
193	F	94.6	Very high	92.5	Very high	58 Å²	58	60.1 Å²	60.1	25%	0.254	35%	0.351	S	S	.	.	H	α-helix	trans	-99	-9.9	-171.5	-60.2	-68.2	0	0	0	114.9	P189 V195 D213 W214 P215	P189-F193 HydrophobicContact CB-CD2 3.93Å; P189-F193 HydrophobicContact CB-CE2 4.09Å; P189-F193 VanDerWaalsContact O-CD2 3.24Å; P189-F193 WeakPolarHBondContact O-CD2 3.49Å; P189-F193 PolarHBondContact O-N 3.08Å; F193-V195 PolarHBondContact O-N 3.41Å; F193-D213 PolarHBondContact O-N 2.89Å; F193-W214 HydrophobicContact CD1-CE3 4.35Å; F193-W214 AromaticContact CD2-CE3 3.78Å; F193-W214 HydrophobicContact CD2-CE3 3.78Å; F193-W214 AromaticContact CD2-CH2 3.62Å; F193-W214 HydrophobicContact CD2-CH2 3.62Å; F193-W214 HydrophobicContact CD2-CZ2 4.39Å; F193-W214 AromaticContact CD2-CZ3 3.27Å; F193-W214 HydrophobicContact CD2-CZ3 3.27Å; F193-W214 HydrophobicContact CE2-CE3 4Å; F193-W214 HydrophobicContact CE2-CH2 4.06Å; F193-W214 AromaticContact CE2-CZ3 3.38Å; F193-W214 HydrophobicContact CE2-CZ3 3.38Å; F193-W214 HydrophobicContact CG-CD2 4.49Å; F193-W214 AromaticContact CG-CE3 3.98Å; F193-W214 HydrophobicContact CG-CE3 3.98Å; F193-W214 HydrophobicContact CG-CH2 4.38Å; F193-W214 AromaticContact CG-CZ3 3.95Å; F193-W214 HydrophobicContact CG-CZ3 3.95Å; F193-W214 HydrophobicContact CZ-CE3 4.38Å; F193-W214 HydrophobicContact CZ-CZ3 4.12Å; F193-P215 HydrophobicContact CE1-CG 4.32Å
194	N	93.8	Very high	91.7	Very high	5 Å²	5	63.8 Å²	63.8	3%	0.027	39%	0.389	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.9	121.1	169.8	-88.2	-78.3	0	0	0	110.9	K129 A132 Y190 L212	K129-N194 WeakPolarHBondContact CE-O 3.47Å; K129-N194 HydrophobicContact CG-CB 4.43Å; A132-N194 WeakPolarHBondContact CB-ND2 3.46Å; Y190-N194 WeakPolarHBondContact O-CB 2.92Å; Y190-N194 PolarHBondContact O-N 3.27Å; Y190-N194 PolarHBondContact O-ND2 2.87Å; N194-L212 WeakPolarHBondContact ND2-CD1 3.38Å; N194-L212 VanDerWaalsContact OD1-CD1 3.28Å; N194-L212 WeakPolarHBondContact OD1-CD1 3.39Å
195	V	93.9	Very high	91.3	Very high	58 Å²	58	64.4 Å²	64.4	35%	0.352	40%	0.395	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127	140.2	-179.2	-176.5	0	0	0	0	109.3	F193 K197 R211 D213	F193-V195 PolarHBondContact O-N 3.41Å; V195-K197 HydrophobicContact CG1-CG 4.32Å; V195-R211 PolarHBondContact N-O 3.43Å; V195-R211 PolarHBondContact O-N 3Å; V195-R211 VanDerWaalsContact O-N 3.09Å; V195-D213 HydrophobicContact CB-CB 4.48Å; V195-D213 HydrophobicContact CG2-CB 4.24Å
196	L	94.6	Very high	90.9	Very high	44 Å²	44	63.5 Å²	63.5	23%	0.23	39%	0.394	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.4	116.3	169.7	-170.1	72.6	0	0	0	108.4	F121 A125 N208	F121-L196 HydrophobicContact CB-CD1 4.16Å; F121-L196 HydrophobicContact CD1-CD1 3.61Å; F121-L196 HydrophobicContact CE1-CD1 4.44Å; F121-L196 HydrophobicContact CG-CD1 4.17Å; A125-L196 HydrophobicContact CB-CB 4.18Å; A125-L196 HydrophobicContact CB-CD2 4.34Å; L196-N208 HydrophobicContact CD1-CB 3.91Å; L196-N208 HydrophobicContact CD2-CB 4.33Å; L196-N208 HydrophobicContact CG-CB 4.13Å
197	K	92.1	Very high	90.6	Very high	59 Å²	59	61.8 Å²	61.8	26%	0.257	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.6	137	175.9	-61.9	-153.4	-170	-178.6	0	110.9	V195 N208 M209 R211 D213	V195-K197 HydrophobicContact CG1-CG 4.32Å; K197-N208 CarbonylContact O-C 3.25Å; K197-N208 WeakPolarHBondContact O-CA 3.27Å; K197-M209 PolarHBondContact N-O 2.86Å; K197-M209 PolarHBondContact O-N 2.96Å; K197-R211 VanDerWaalsContact NZ-NH2 3.1Å; K197-D213 VanDerWaalsContact CE-CG 3.47Å; K197-D213 VanDerWaalsContact CE-OD2 3.22Å; K197-D213 WeakPolarHBondContact CE-OD2 3.24Å; K197-D213 IonicContact NZ-OD1 3.57Å; K197-D213 PolarHBondContact NZ-OD1 3.42Å; K197-D213 IonicContact NZ-OD2 2.74Å; K197-D213 PolarHBondContact NZ-OD2 2.87Å
198	S	92.4	Very high	90.4	Very high	83 Å²	83	64 Å²	64	58%	0.58	40%	0.396	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-92.1	144.9	177.4	-54.6	0	0	0	0	111.1	G207 N208	S198-G207 CarbonylContact C-O 3.57Å; S198-G207 WeakPolarHBondContact CA-O 3.23Å; S198-N208 WeakPolarHBondContact CB-OD1 3.42Å; S198-N208 PolarHBondContact OG-OD1 3.07Å
199	F	88.3	Confident	90.1	Very high	77 Å²	77	65.3 Å²	65.3	34%	0.338	40%	0.399	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.6	145.7	177.8	66.5	-87.2	0	0	0	110.9	K201 G207 M209	F199-K201 HydrophobicContact CD2-CG 4.32Å; F199-K201 HydrophobicContact CE2-CG 3.74Å; F199-K201 HydrophobicContact CZ-CG 4.41Å; F199-G207 WeakPolarHBondContact CD1-O 3.45Å; F199-G207 PolarHBondContact N-O 3.48Å; F199-G207 PolarHBondContact O-N 2.92Å; F199-M209 HydrophobicContact CD1-CB 4.23Å; F199-M209 HydrophobicContact CE1-CB 4.06Å
200	P	88.9	Confident	89.9	Confident	115 Å²	115	65.8 Å²	65.8	75%	0.747	40%	0.402	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-72.5	131.2	176	29.1	-32.7	0	0	0	110.6
201	K	84.8	Confident	89.7	Confident	55 Å²	55	69.2 Å²	69.2	24%	0.239	42%	0.415	C	S	.	.			trans	-91.6	155	173.1	-71.5	176	161.6	178.3	0	110.4	D120 F199 N203 G204 T205	D120-K201 VanDerWaalsContact CB-NZ 3.33Å; D120-K201 VanDerWaalsContact CG-NZ 3.28Å; D120-K201 IonicContact OD2-NZ 3.96Å; D120-K201 PolarHBondContact OD2-NZ 3.12Å; F199-K201 HydrophobicContact CD2-CG 4.32Å; F199-K201 HydrophobicContact CE2-CG 3.74Å; F199-K201 HydrophobicContact CZ-CG 4.41Å; K201-N203 PolarHBondContact O-N 3.28Å; K201-G204 PolarHBondContact O-N 3.23Å; K201-T205 WeakPolarHBondContact CB-O 3.32Å; K201-T205 PolarHBondContact N-O 3.32Å
202	G	78.8	Confident	89.5	Confident	85 Å²	85	69.2 Å²	69.2	88%	0.876	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.5	-21.2	179.5	0	0	0	0	0	115	G204	G202-G204 VanDerWaalsContact C-N 3.29Å; G202-G204 PolarHBondContact O-N 2.94Å
203	N	83.1	Confident	89.4	Confident	155 Å²	155	68.2 Å²	68.2	83%	0.829	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.2	12	178.5	-63.8	7.3	0	0	0	113.3	K201 T205	K201-N203 PolarHBondContact O-N 3.28Å; N203-T205 PolarHBondContact O-N 3.46Å
204	G	81.3	Confident	89.3	Confident	76 Å²	76	67.1 Å²	67.1	78%	0.784	40%	0.399	S	S	*	.	S	Bend	trans	77.8	2.3	-178.4	0	0	0	0	0	114.9	K201 G202	K201-G204 PolarHBondContact O-N 3.23Å; G202-G204 VanDerWaalsContact C-N 3.29Å; G202-G204 PolarHBondContact O-N 2.94Å
205	T	88.1	Confident	89.2	Confident	78 Å²	78	71.9 Å²	71.9	48%	0.479	43%	0.43	S	S	.	.	P	Polyproline II helix	trans	-90.2	163	174	56.7	0	0	0	0	111.6	K201 N203	K201-T205 WeakPolarHBondContact CB-O 3.32Å; K201-T205 PolarHBondContact N-O 3.32Å; N203-T205 PolarHBondContact O-N 3.46Å
206	V	89.9	Confident	89.2	Confident	96 Å²	96	71.4 Å²	71.4	58%	0.582	43%	0.429	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-100.5	124.7	173.8	-177.4	0	0	0	0	108.7
207	G	88.7	Confident	89.1	Confident	0 Å²	0	76 Å²	76	0%	0	45%	0.449	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	161.2	170.1	0	0	0	0	0	111.6	S198 F199	S198-G207 CarbonylContact C-O 3.57Å; S198-G207 WeakPolarHBondContact CA-O 3.23Å; F199-G207 WeakPolarHBondContact CD1-O 3.45Å; F199-G207 PolarHBondContact N-O 3.48Å; F199-G207 PolarHBondContact O-N 2.92Å
208	N	92.4	Very high	89.2	Confident	46 Å²	46	79.1 Å²	79.1	25%	0.246	47%	0.465	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.2	143.1	175.1	-61.7	-53.1	0	0	0	111	D120 F121 L196 K197 S198	D120-N208 PolarHBondContact OD1-N 3.33Å; F121-N208 WeakPolarHBondContact CB-O 3.24Å; F121-N208 PolarHBondContact N-O 3.29Å; L196-N208 HydrophobicContact CD1-CB 3.91Å; L196-N208 HydrophobicContact CD2-CB 4.33Å; L196-N208 HydrophobicContact CG-CB 4.13Å; K197-N208 CarbonylContact O-C 3.25Å; K197-N208 WeakPolarHBondContact O-CA 3.27Å; S198-N208 WeakPolarHBondContact CB-OD1 3.42Å; S198-N208 PolarHBondContact OG-OD1 3.07Å
209	M	89.3	Confident	89.2	Confident	96 Å²	96	76.5 Å²	76.5	47%	0.473	45%	0.448	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.2	131.6	175	-176	169.3	79.5	0	0	109.9	K197 F199 R211	K197-M209 PolarHBondContact N-O 2.86Å; K197-M209 PolarHBondContact O-N 2.96Å; F199-M209 HydrophobicContact CD1-CB 4.23Å; F199-M209 HydrophobicContact CE1-CB 4.06Å; M209-R211 HydrophobicContact CE-CB 4.39Å; M209-R211 HydrophobicContact CE-CG 4.44Å
210	C	90.9	Very high	89.4	Confident	38 Å²	38	75.6 Å²	75.6	26%	0.257	45%	0.445	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.4	120	172	-178.1	0	0	0	0	109	F121 C128	F121-C210 HydrophobicContact CD1-CB 4.44Å; F121-C210 HydrophobicContact CD2-CB 3.97Å; F121-C210 HydrophobicContact CE2-CB 4.25Å; F121-C210 HydrophobicContact CG-CB 4.08Å; C128-C210 WeakPolarHBondContact CA-SG 3.13Å; C128-C210 HydrophobicContact CB-CB 3.74Å; C128-C210 WeakPolarHBondContact CB-SG 3.38Å; C128-C210 PolarHBondContact O-SG 3.16Å; C128-C210 VanDerWaalsContact SG-CA 3.57Å; C128-C210 WeakPolarHBondContact SG-CB 3.17Å; C128-C210 CovalentContact SG-SG 2.03Å; C128-C210 PolarHBondContact SG-SG 3.04Å
211	R	89.1	Confident	89.7	Confident	107 Å²	107	72.4 Å²	72.4	40%	0.404	42%	0.42	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-142	154.4	176.4	65.8	172.6	178.2	131	-9.7	112	V195 K197 M209 D213	V195-R211 PolarHBondContact N-O 3.43Å; V195-R211 PolarHBondContact O-N 3Å; V195-R211 VanDerWaalsContact O-N 3.09Å; K197-R211 VanDerWaalsContact NZ-NH2 3.1Å; M209-R211 HydrophobicContact CE-CB 4.39Å; M209-R211 HydrophobicContact CE-CG 4.44Å; R211-D213 IonicContact NH1-OD1 2.69Å
212	L	90	Very high	90.1	Very high	38 Å²	38	74.1 Å²	74.1	20%	0.199	44%	0.436	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.1	132.3	166.8	-80.1	82.4	0	0	0	108.8	Y190 N194 W214	Y190-L212 HydrophobicContact CD1-CD1 4.16Å; Y190-L212 HydrophobicContact CD1-CD2 4.13Å; Y190-L212 HydrophobicContact CE1-CD1 4.08Å; Y190-L212 HydrophobicContact CE1-CD2 4.01Å; N194-L212 WeakPolarHBondContact ND2-CD1 3.38Å; N194-L212 VanDerWaalsContact OD1-CD1 3.28Å; N194-L212 WeakPolarHBondContact OD1-CD1 3.39Å; L212-W214 HydrophobicContact CD2-CZ2 3.7Å
213	D	91.8	Very high	90.9	Very high	63 Å²	63	71.1 Å²	71.1	34%	0.337	40%	0.398	S	S	.	.			trans	-121.9	94	177.5	-159.2	46	0	0	0	108.6	F193 V195 K197 R211	F193-D213 PolarHBondContact O-N 2.89Å; V195-D213 HydrophobicContact CB-CB 4.48Å; V195-D213 HydrophobicContact CG2-CB 4.24Å; K197-D213 VanDerWaalsContact CE-CG 3.47Å; K197-D213 VanDerWaalsContact CE-OD2 3.22Å; K197-D213 WeakPolarHBondContact CE-OD2 3.24Å; K197-D213 IonicContact NZ-OD1 3.57Å; K197-D213 PolarHBondContact NZ-OD1 3.42Å; K197-D213 IonicContact NZ-OD2 2.74Å; K197-D213 PolarHBondContact NZ-OD2 2.87Å; R211-D213 IonicContact NH1-OD1 2.69Å
214	W	92.5	Very high	91.4	Very high	36 Å²	36	65.3 Å²	65.3	14%	0.136	36%	0.364	C	S	.	.			trans	-82.1	145.2	179.4	-68	102.5	0	0	0	110.9	P189 F193 L212 S216 A219 E220 W223	P189-W214 HydrophobicContact CB-CH2 3.82Å; P189-W214 HydrophobicContact CB-CZ3 4.46Å; F193-W214 HydrophobicContact CD1-CE3 4.35Å; F193-W214 AromaticContact CD2-CE3 3.78Å; F193-W214 HydrophobicContact CD2-CE3 3.78Å; F193-W214 AromaticContact CD2-CH2 3.62Å; F193-W214 HydrophobicContact CD2-CH2 3.62Å; F193-W214 HydrophobicContact CD2-CZ2 4.39Å; F193-W214 AromaticContact CD2-CZ3 3.27Å; F193-W214 HydrophobicContact CD2-CZ3 3.27Å; F193-W214 HydrophobicContact CE2-CE3 4Å; F193-W214 HydrophobicContact CE2-CH2 4.06Å; F193-W214 AromaticContact CE2-CZ3 3.38Å; F193-W214 HydrophobicContact CE2-CZ3 3.38Å; F193-W214 HydrophobicContact CG-CD2 4.49Å; F193-W214 AromaticContact CG-CE3 3.98Å; F193-W214 HydrophobicContact CG-CE3 3.98Å; F193-W214 HydrophobicContact CG-CH2 4.38Å; F193-W214 AromaticContact CG-CZ3 3.95Å; F193-W214 HydrophobicContact CG-CZ3 3.95Å; F193-W214 HydrophobicContact CZ-CE3 4.38Å; F193-W214 HydrophobicContact CZ-CZ3 4.12Å; L212-W214 HydrophobicContact CD2-CZ2 3.7Å; W214-S216 PolarHBondContact O-N 3.41Å; W214-A219 HydrophobicContact CE3-CB 4.18Å; W214-E220 HydrophobicContact CB-CB 3.99Å; W214-E220 HydrophobicContact CG-CB 3.81Å; W214-E220 HydrophobicContact CG-CG 4.32Å; W214-W223 HydrophobicContact CH2-CB 3.89Å; W214-W223 AromaticContact CH2-CD1 3.94Å; W214-W223 AromaticContact CH2-CD2 3.59Å; W214-W223 HydrophobicContact CH2-CD2 3.59Å; W214-W223 HydrophobicContact CH2-CE3 4.07Å; W214-W223 AromaticContact CH2-CG 3.51Å; W214-W223 HydrophobicContact CH2-CG 3.51Å; W214-W223 HydrophobicContact CZ2-CB 3.76Å; W214-W223 AromaticContact CZ2-CD1 3.24Å; W214-W223 AromaticContact CZ2-CD2 3.74Å; W214-W223 HydrophobicContact CZ2-CD2 3.74Å; W214-W223 AromaticContact CZ2-CE2 3.91Å; W214-W223 AromaticContact CZ2-CG 3.27Å; W214-W223 HydrophobicContact CZ2-CG 3.27Å; W214-W223 AromaticContact CZ2-NE1 3.59Å; W214-W223 HydrophobicContact CZ3-CB 4.5Å
215	P	92.6	Very high	92.1	Very high	105 Å²	105	64 Å²	64	68%	0.682	34%	0.341	S	S	*	.	S	Bend	trans	-71.3	-18.6	179.9	29	-35.1	0	0	0	113.4	F193	F193-P215 HydrophobicContact CE1-CG 4.32Å
216	S	94.5	Very high	92.4	Very high	48 Å²	48	63.8 Å²	63.8	34%	0.336	34%	0.336	S	S	.	.	S	Bend	trans	-150.6	151.7	178.2	60.8	0	0	0	0	110.9	W214 Q218 A219 E220	W214-S216 PolarHBondContact O-N 3.41Å; S216-Q218 VanDerWaalsContact C-N 3.27Å; S216-Q218 PolarHBondContact O-N 3.46Å; S216-A219 PolarHBondContact O-N 2.93Å; S216-A219 VanDerWaalsContact OG-CB 3.23Å; S216-A219 WeakPolarHBondContact OG-CB 3.33Å; S216-A219 PolarHBondContact OG-N 3.05Å; S216-E220 PolarHBondContact O-N 3.36Å
217	E	91.2	Very high	92.7	Very high	140 Å²	140	59.5 Å²	59.5	65%	0.654	31%	0.31	S	S	*	.	H	α-helix	trans	-61.5	-37	174.5	-66.1	-176.6	172.2	0	0	111.4	A219 E220 Q221	E217-A219 VanDerWaalsContact C-N 3.3Å; E217-A219 PolarHBondContact O-N 2.99Å; E217-E220 PolarHBondContact O-N 2.81Å; E217-Q221 WeakPolarHBondContact O-CG 3.47Å; E217-Q221 PolarHBondContact O-N 3.43Å
218	Q	94.1	Very high	93	Very high	124 Å²	124	60.8 Å²	60.8	58%	0.579	32%	0.317	S	S	*	.	H	α-helix	trans	-63.2	-37.5	176.9	-62.4	82.2	11.2	0	0	111.7	S216 T222	S216-Q218 VanDerWaalsContact C-N 3.27Å; S216-Q218 PolarHBondContact O-N 3.46Å; Q218-T222 WeakPolarHBondContact O-CB 3.47Å; Q218-T222 PolarHBondContact O-N 3.05Å; Q218-T222 PolarHBondContact O-OG1 3.19Å
219	A	94.1	Very high	93.2	Very high	29 Å²	29	62.2 Å²	62.2	24%	0.24	32%	0.324	C	S	.	.	H	α-helix	trans	-66.8	-41.7	176	0	0	0	0	0	111.6	W214 S216 E217 W223	W214-A219 HydrophobicContact CE3-CB 4.18Å; S216-A219 PolarHBondContact O-N 2.93Å; S216-A219 VanDerWaalsContact OG-CB 3.23Å; S216-A219 WeakPolarHBondContact OG-CB 3.33Å; S216-A219 PolarHBondContact OG-N 3.05Å; E217-A219 VanDerWaalsContact C-N 3.3Å; E217-A219 PolarHBondContact O-N 2.99Å; A219-W223 VanDerWaalsContact O-CB 3.24Å; A219-W223 WeakPolarHBondContact O-CB 3.39Å; A219-W223 PolarHBondContact O-N 2.91Å
220	E	91.6	Very high	93.5	Very high	57 Å²	57	59.7 Å²	59.7	27%	0.266	31%	0.312	S	S	.	.	H	α-helix	trans	-60.2	-50.8	175.3	-177	171.4	-179.9	0	0	111.7	W214 S216 E217 W223 Y224 A357	W214-E220 HydrophobicContact CB-CB 3.99Å; W214-E220 HydrophobicContact CG-CB 3.81Å; W214-E220 HydrophobicContact CG-CG 4.32Å; S216-E220 PolarHBondContact O-N 3.36Å; E217-E220 PolarHBondContact O-N 2.81Å; E220-W223 WeakPolarHBondContact O-CB 3.48Å; E220-W223 PolarHBondContact O-N 3.37Å; E220-Y224 HydrophobicContact CG-CD2 3.8Å; E220-Y224 HydrophobicContact CG-CE2 3.66Å; E220-Y224 WeakPolarHBondContact O-CD2 2.9Å; E220-Y224 PolarHBondContact O-N 3.14Å; E220-A357 HydrophobicContact CG-CB 4.17Å
221	Q	94.3	Very high	93.7	Very high	48 Å²	48	58 Å²	58	22%	0.224	30%	0.3	C	S	.	.	H	α-helix	trans	-59.9	-49.4	177.8	-71	169.3	-1.1	0	0	111.6	E217 W223 Y224 V225 A357 F358	E217-Q221 WeakPolarHBondContact O-CG 3.47Å; E217-Q221 PolarHBondContact O-N 3.43Å; Q221-W223 PolarHBondContact O-N 2.85Å; Q221-Y224 PolarHBondContact O-N 3.21Å; Q221-V225 WeakPolarHBondContact O-CB 3.46Å; Q221-V225 VanDerWaalsContact O-CG2 3.26Å; Q221-V225 WeakPolarHBondContact O-CG2 3.48Å; Q221-V225 PolarHBondContact O-N 2.96Å; Q221-A357 HydrophobicContact CG-CB 4.25Å; Q221-A357 WeakPolarHBondContact CG-O 3.43Å; Q221-A357 PolarHBondContact NE2-O 3.32Å; Q221-F358 HydrophobicContact CB-CE1 4.48Å; Q221-F358 HydrophobicContact CB-CZ 4.38Å; Q221-F358 HydrophobicContact CG-CD1 4.25Å; Q221-F358 HydrophobicContact CG-CE1 4.2Å; Q221-F358 HydrophobicContact CG-CZ 4.45Å
222	T	94.9	Very high	93.9	Very high	92 Å²	92	53.4 Å²	53.4	56%	0.564	28%	0.283	S	S	*	.	H	α-helix	trans	-57.7	-42.5	178.8	-60.9	0	0	0	0	110.5	Q218 L226	Q218-T222 WeakPolarHBondContact O-CB 3.47Å; Q218-T222 PolarHBondContact O-N 3.05Å; Q218-T222 PolarHBondContact O-OG1 3.19Å; T222-L226 WeakPolarHBondContact O-CB 3.3Å; T222-L226 PolarHBondContact O-N 3.22Å
223	W	94.6	Very high	94.2	Very high	21 Å²	21	56.7 Å²	56.7	8%	0.08	30%	0.296	C	S	.	.	H	α-helix	trans	-62.3	-52.4	179.4	179	-108.2	0	0	0	112.8	V186 P189 Y190 W214 A219 E220 Q221 V225 L226 L227	V186-W223 VanDerWaalsContact O-CH2 3.24Å; V186-W223 WeakPolarHBondContact O-CH2 3.49Å; P189-W223 HydrophobicContact CB-CE3 4.41Å; P189-W223 HydrophobicContact CB-CH2 3.73Å; P189-W223 HydrophobicContact CB-CZ2 4.03Å; P189-W223 HydrophobicContact CB-CZ3 3.96Å; P189-W223 HydrophobicContact CG-CE3 4.3Å; P189-W223 HydrophobicContact CG-CH2 3.48Å; P189-W223 VanDerWaalsContact CG-CH2 3.48Å; P189-W223 HydrophobicContact CG-CZ2 4.28Å; P189-W223 HydrophobicContact CG-CZ3 3.51Å; Y190-W223 AromaticContact CD2-CZ2 3.9Å; Y190-W223 HydrophobicContact CD2-CZ2 3.9Å; Y190-W223 AromaticContact CE2-CZ2 3.6Å; Y190-W223 HydrophobicContact CE2-CZ2 3.6Å; W214-W223 HydrophobicContact CH2-CB 3.89Å; W214-W223 AromaticContact CH2-CD1 3.94Å; W214-W223 AromaticContact CH2-CD2 3.59Å; W214-W223 HydrophobicContact CH2-CD2 3.59Å; W214-W223 HydrophobicContact CH2-CE3 4.07Å; W214-W223 AromaticContact CH2-CG 3.51Å; W214-W223 HydrophobicContact CH2-CG 3.51Å; W214-W223 HydrophobicContact CZ2-CB 3.76Å; W214-W223 AromaticContact CZ2-CD1 3.24Å; W214-W223 AromaticContact CZ2-CD2 3.74Å; W214-W223 HydrophobicContact CZ2-CD2 3.74Å; W214-W223 AromaticContact CZ2-CE2 3.91Å; W214-W223 AromaticContact CZ2-CG 3.27Å; W214-W223 HydrophobicContact CZ2-CG 3.27Å; W214-W223 AromaticContact CZ2-NE1 3.59Å; W214-W223 HydrophobicContact CZ3-CB 4.5Å; A219-W223 VanDerWaalsContact O-CB 3.24Å; A219-W223 WeakPolarHBondContact O-CB 3.39Å; A219-W223 PolarHBondContact O-N 2.91Å; E220-W223 WeakPolarHBondContact O-CB 3.48Å; E220-W223 PolarHBondContact O-N 3.37Å; Q221-W223 PolarHBondContact O-N 2.85Å; W223-V225 PolarHBondContact O-N 3.33Å; W223-L226 PolarHBondContact O-N 2.96Å; W223-L227 HydrophobicContact CD2-CD1 4.39Å; W223-L227 HydrophobicContact CD2-CG 4.37Å; W223-L227 HydrophobicContact CH2-CD2 4.26Å; W223-L227 HydrophobicContact CZ2-CD1 3.96Å; W223-L227 HydrophobicContact CZ2-CD2 4.02Å; W223-L227 HydrophobicContact CZ2-CG 4.18Å; W223-L227 VanDerWaalsContact NE1-CD1 3.32Å; W223-L227 WeakPolarHBondContact O-CG 3.37Å; W223-L227 PolarHBondContact O-N 3.3Å
224	Y	93.9	Very high	94.4	Very high	34 Å²	34	58.1 Å²	58.1	13%	0.133	30%	0.303	C	S	.	.	H	α-helix	trans	-67.5	-36.4	-178.3	-74.5	-66.6	0	0	0	112.6	E220 Q221 L227 L228 N353 A357	E220-Y224 HydrophobicContact CG-CD2 3.8Å; E220-Y224 HydrophobicContact CG-CE2 3.66Å; E220-Y224 WeakPolarHBondContact O-CD2 2.9Å; E220-Y224 PolarHBondContact O-N 3.14Å; Q221-Y224 PolarHBondContact O-N 3.21Å; Y224-L227 PolarHBondContact O-N 3.42Å; Y224-L228 WeakPolarHBondContact O-CB 3.45Å; Y224-L228 PolarHBondContact O-N 3.15Å; Y224-N353 HydrophobicContact CD1-CB 3.76Å; Y224-N353 HydrophobicContact CE1-CB 3.88Å; Y224-A357 HydrophobicContact CD2-CB 3.62Å; Y224-A357 HydrophobicContact CE2-CB 4.41Å; Y224-A357 HydrophobicContact CG-CB 4.26Å
225	V	95.4	Very high	94.5	Very high	48 Å²	48	56.6 Å²	56.6	29%	0.291	30%	0.297	S	S	.	.	H	α-helix	trans	-64.5	-43.4	172.7	171.7	0	0	0	0	111.1	Q221 W223 L227 L228 I229 T354 F358	Q221-V225 WeakPolarHBondContact O-CB 3.46Å; Q221-V225 VanDerWaalsContact O-CG2 3.26Å; Q221-V225 WeakPolarHBondContact O-CG2 3.48Å; Q221-V225 PolarHBondContact O-N 2.96Å; W223-V225 PolarHBondContact O-N 3.33Å; V225-L227 PolarHBondContact O-N 3.3Å; V225-L228 WeakPolarHBondContact O-CB 3.49Å; V225-L228 PolarHBondContact O-N 3.41Å; V225-I229 HydrophobicContact CG1-CD1 3.85Å; V225-I229 WeakPolarHBondContact O-CG1 3.43Å; V225-I229 PolarHBondContact O-N 3.24Å; V225-T354 HydrophobicContact CG2-CG2 4.43Å; V225-F358 HydrophobicContact CG2-CE2 3.87Å; V225-F358 HydrophobicContact CG2-CZ 3.97Å
226	L	95.7	Very high	94.6	Very high	73 Å²	73	51.6 Å²	51.6	38%	0.382	27%	0.265	S	S	.	.	H	α-helix	trans	-60.9	-45.8	177.2	-175.4	71.6	0	0	0	111.2	T222 W223 I229 I230	T222-L226 WeakPolarHBondContact O-CB 3.3Å; T222-L226 PolarHBondContact O-N 3.22Å; W223-L226 PolarHBondContact O-N 2.96Å; L226-I229 PolarHBondContact O-N 3.26Å; L226-I230 HydrophobicContact CD1-CD1 3.65Å; L226-I230 HydrophobicContact CD1-CG1 4.23Å; L226-I230 HydrophobicContact CD2-CD1 4.34Å; L226-I230 HydrophobicContact CG-CD1 3.72Å; L226-I230 HydrophobicContact CG-CG1 4.4Å; L226-I230 WeakPolarHBondContact O-CB 3.32Å; L226-I230 WeakPolarHBondContact O-CG1 3.27Å; L226-I230 PolarHBondContact O-N 3.38Å
227	L	94.4	Very high	94.6	Very high	7 Å²	7	53 Å²	53	4%	0.037	27%	0.272	C	S	.	.	H	α-helix	trans	-62.2	-43.5	176.1	-70.3	-176.8	0	0	0	112.1	V186 M187 Y190 W223 Y224 V225 I229 I230 L231	V186-L227 HydrophobicContact CG1-CD2 4.4Å; M187-L227 HydrophobicContact CE-CD2 3.66Å; Y190-L227 HydrophobicContact CE2-CD1 4.3Å; Y190-L227 WeakPolarHBondContact OH-CD1 3.42Å; W223-L227 HydrophobicContact CD2-CD1 4.39Å; W223-L227 HydrophobicContact CD2-CG 4.37Å; W223-L227 HydrophobicContact CH2-CD2 4.26Å; W223-L227 HydrophobicContact CZ2-CD1 3.96Å; W223-L227 HydrophobicContact CZ2-CD2 4.02Å; W223-L227 HydrophobicContact CZ2-CG 4.18Å; W223-L227 VanDerWaalsContact NE1-CD1 3.32Å; W223-L227 WeakPolarHBondContact O-CG 3.37Å; W223-L227 PolarHBondContact O-N 3.3Å; Y224-L227 PolarHBondContact O-N 3.42Å; V225-L227 PolarHBondContact O-N 3.3Å; L227-I229 VanDerWaalsContact C-N 3.3Å; L227-I229 PolarHBondContact O-N 3.49Å; L227-I230 PolarHBondContact O-N 3.27Å; L227-L231 HydrophobicContact CD2-CD1 3.82Å; L227-L231 WeakPolarHBondContact O-CA 3.4Å; L227-L231 VanDerWaalsContact O-CB 3.26Å; L227-L231 WeakPolarHBondContact O-CB 3.47Å; L227-L231 PolarHBondContact O-N 3.26Å
228	L	95.3	Very high	94.8	Very high	27 Å²	27	48.8 Å²	48.8	14%	0.141	26%	0.255	C	S	.	.	H	α-helix	trans	-58.6	-41.7	175.3	173.8	67.7	0	0	0	111.4	Y224 V225 F232 F233 Y350 T354	Y224-L228 WeakPolarHBondContact O-CB 3.45Å; Y224-L228 PolarHBondContact O-N 3.15Å; V225-L228 WeakPolarHBondContact O-CB 3.49Å; V225-L228 PolarHBondContact O-N 3.41Å; L228-F232 HydrophobicContact CD1-CB 4.2Å; L228-F232 HydrophobicContact CD1-CD1 3.86Å; L228-F232 HydrophobicContact CD1-CG 4.32Å; L228-F232 WeakPolarHBondContact O-CA 3.27Å; L228-F232 VanDerWaalsContact O-CB 3.24Å; L228-F232 WeakPolarHBondContact O-CB 3.39Å; L228-F232 PolarHBondContact O-N 3.35Å; L228-F232 VanDerWaalsContact O-N 3.17Å; L228-F233 HydrophobicContact CD1-CD2 4.09Å; L228-F233 HydrophobicContact CD1-CE2 3.74Å; L228-F233 HydrophobicContact CD2-CD2 4.38Å; L228-F233 HydrophobicContact CD2-CE2 3.75Å; L228-F233 HydrophobicContact CG-CD2 3.77Å; L228-F233 HydrophobicContact CG-CE2 3.55Å; L228-F233 PolarHBondContact O-N 3.18Å; L228-Y350 HydrophobicContact CD1-CG 4.32Å; L228-T354 HydrophobicContact CD2-CG2 4.37Å
229	I	96.3	Very high	94.8	Very high	75 Å²	75	42.9 Å²	42.9	39%	0.385	23%	0.228	S	C	.	.	I	π-helix	trans	-69.8	-52.6	178.4	-68	168.5	0	0	0	111	V225 L226 L227 F233 I234	V225-I229 HydrophobicContact CG1-CD1 3.85Å; V225-I229 WeakPolarHBondContact O-CG1 3.43Å; V225-I229 PolarHBondContact O-N 3.24Å; L226-I229 PolarHBondContact O-N 3.26Å; L227-I229 VanDerWaalsContact C-N 3.3Å; L227-I229 PolarHBondContact O-N 3.49Å; I229-F233 PolarHBondContact O-N 2.92Å; I229-I234 HydrophobicContact CG2-CD1 3.71Å; I229-I234 HydrophobicContact CG2-CG1 4.05Å; I229-I234 WeakPolarHBondContact O-CB 3.45Å; I229-I234 WeakPolarHBondContact O-CG1 3.43Å; I229-I234 PolarHBondContact O-N 3.46Å
230	I	95.8	Very high	94.7	Very high	43 Å²	43	46 Å²	46	22%	0.221	24%	0.24	C	C	.	.	I	π-helix	trans	-71.7	-38.6	-171.7	-68.3	-179.5	0	0	0	112.2	F144 L226 L227 P235	F144-I230 HydrophobicContact CE1-CG2 4.26Å; F144-I230 HydrophobicContact CZ-CG2 3.86Å; L226-I230 HydrophobicContact CD1-CD1 3.65Å; L226-I230 HydrophobicContact CD1-CG1 4.23Å; L226-I230 HydrophobicContact CD2-CD1 4.34Å; L226-I230 HydrophobicContact CG-CD1 3.72Å; L226-I230 HydrophobicContact CG-CG1 4.4Å; L226-I230 WeakPolarHBondContact O-CB 3.32Å; L226-I230 WeakPolarHBondContact O-CG1 3.27Å; L226-I230 PolarHBondContact O-N 3.38Å; L227-I230 PolarHBondContact O-N 3.27Å; I230-P235 WeakPolarHBondContact O-CD 3.45Å; I230-P235 WeakPolarHBondContact O-CG 3.31Å
231	L	94.9	Very high	94.8	Very high	3 Å²	3	48 Å²	48	2%	0.016	25%	0.251	C	S	.	.	I	π-helix	trans	-104.7	-8.1	-171.9	-58.5	177	0	0	0	113.8	T143 F144 M187 L227 F342 Y350	T143-L231 VanDerWaalsContact CG2-O 3.3Å; T143-L231 WeakPolarHBondContact CG2-O 3.48Å; F144-L231 HydrophobicContact CE1-CD2 4.11Å; F144-L231 HydrophobicContact CE2-CD2 4.21Å; F144-L231 HydrophobicContact CZ-CD2 3.69Å; M187-L231 HydrophobicContact CE-CD1 3.53Å; L227-L231 HydrophobicContact CD2-CD1 3.82Å; L227-L231 WeakPolarHBondContact O-CA 3.4Å; L227-L231 VanDerWaalsContact O-CB 3.26Å; L227-L231 WeakPolarHBondContact O-CB 3.47Å; L227-L231 PolarHBondContact O-N 3.26Å; L231-F342 WeakPolarHBondContact O-CZ 3.22Å; L231-Y350 HydrophobicContact CB-CE1 4.38Å; L231-Y350 VanDerWaalsContact CB-OH 3.23Å; L231-Y350 WeakPolarHBondContact CB-OH 3.35Å
232	F	94.9	Very high	94.7	Very high	10 Å²	10	46.1 Å²	46.1	4%	0.044	24%	0.243	C	C	.	.	I	π-helix	trans	-126.9	-60.5	179.5	-175.6	-100.2	0	0	0	112.7	L228 G236 F342 F343 W346 M347 Y350	L228-F232 HydrophobicContact CD1-CB 4.2Å; L228-F232 HydrophobicContact CD1-CD1 3.86Å; L228-F232 HydrophobicContact CD1-CG 4.32Å; L228-F232 WeakPolarHBondContact O-CA 3.27Å; L228-F232 VanDerWaalsContact O-CB 3.24Å; L228-F232 WeakPolarHBondContact O-CB 3.39Å; L228-F232 PolarHBondContact O-N 3.35Å; L228-F232 VanDerWaalsContact O-N 3.17Å; F232-G236 WeakPolarHBondContact O-CA 3.49Å; F232-G236 PolarHBondContact O-N 3.4Å; F232-F342 AromaticContact CD2-CE1 3.77Å; F232-F342 HydrophobicContact CD2-CE1 3.77Å; F232-F342 HydrophobicContact CD2-CZ 4.14Å; F232-F342 HydrophobicContact CE2-CE1 4.17Å; F232-F343 HydrophobicContact CE1-CD1 4.24Å; F232-F343 HydrophobicContact CE1-CE1 4.28Å; F232-F343 AromaticContact CE2-CD1 3.81Å; F232-F343 HydrophobicContact CE2-CD1 3.81Å; F232-F343 HydrophobicContact CE2-CE1 4.3Å; F232-F343 AromaticContact CZ-CD1 3.47Å; F232-F343 HydrophobicContact CZ-CD1 3.47Å; F232-F343 VanDerWaalsContact CZ-CD1 3.47Å; F232-F343 AromaticContact CZ-CE1 3.92Å; F232-F343 HydrophobicContact CZ-CE1 3.92Å; F232-W346 HydrophobicContact CD2-CB 4.14Å; F232-W346 HydrophobicContact CE2-CB 4.22Å; F232-M347 HydrophobicContact CE1-CG 4.48Å; F232-M347 HydrophobicContact CE2-CB 3.97Å; F232-M347 HydrophobicContact CZ-CB 3.62Å; F232-M347 HydrophobicContact CZ-CG 3.87Å; F232-Y350 HydrophobicContact CB-CD2 3.84Å; F232-Y350 HydrophobicContact CB-CE2 3.98Å; F232-Y350 HydrophobicContact CB-CG 4.31Å; F232-Y350 AromaticContact CD2-CD2 3.79Å; F232-Y350 HydrophobicContact CD2-CD2 3.79Å; F232-Y350 HydrophobicContact CD2-CE2 4.17Å; F232-Y350 AromaticContact CG-CD2 4Å; F232-Y350 HydrophobicContact CG-CD2 4Å; F232-Y350 HydrophobicContact CG-CE2 4.46Å
233	F	95.5	Very high	94.4	Very high	108 Å²	108	41.9 Å²	41.9	47%	0.474	22%	0.217	S	C	.	.	I	π-helix	trans	-69.7	-52.5	-175.1	-76.7	-64.8	0	0	0	113.8	L228 I229 G236 V237	L228-F233 HydrophobicContact CD1-CD2 4.09Å; L228-F233 HydrophobicContact CD1-CE2 3.74Å; L228-F233 HydrophobicContact CD2-CD2 4.38Å; L228-F233 HydrophobicContact CD2-CE2 3.75Å; L228-F233 HydrophobicContact CG-CD2 3.77Å; L228-F233 HydrophobicContact CG-CE2 3.55Å; L228-F233 PolarHBondContact O-N 3.18Å; I229-F233 PolarHBondContact O-N 2.92Å; F233-G236 PolarHBondContact O-N 3.08Å; F233-V237 WeakPolarHBondContact O-CB 3.44Å; F233-V237 VanDerWaalsContact O-CG2 3.31Å; F233-V237 WeakPolarHBondContact O-CG2 3.45Å; F233-V237 PolarHBondContact O-N 2.79Å
234	I	95.8	Very high	94.1	Very high	93 Å²	93	42.8 Å²	42.8	48%	0.477	23%	0.233	S	C	.	.	H	α-helix	trans	-59.5	-50.8	179.9	-67.7	170.7	0	0	0	110.6	I229 G236 V237 V238	I229-I234 HydrophobicContact CG2-CD1 3.71Å; I229-I234 HydrophobicContact CG2-CG1 4.05Å; I229-I234 WeakPolarHBondContact O-CB 3.45Å; I229-I234 WeakPolarHBondContact O-CG1 3.43Å; I229-I234 PolarHBondContact O-N 3.46Å; I234-G236 VanDerWaalsContact C-N 3.34Å; I234-G236 PolarHBondContact O-N 3.03Å; I234-V237 PolarHBondContact O-N 3.43Å; I234-V238 HydrophobicContact CG2-CG2 4.49Å; I234-V238 VanDerWaalsContact O-CG2 3.3Å; I234-V238 WeakPolarHBondContact O-CG2 3.47Å; I234-V238 PolarHBondContact O-N 2.92Å
235	P	95.4	Very high	94	Very high	3 Å²	3	43.8 Å²	43.8	2%	0.019	24%	0.241	C	C	.	.	H	α-helix	trans	-57.7	-45	175.1	-28.8	38.9	0	0	0	112.8	T143 V147 I230 V238 M239 F342	T143-P235 HydrophobicContact CG2-CB 3.57Å; T143-P235 HydrophobicContact CG2-CG 3.46Å; T143-P235 VanDerWaalsContact CG2-CG 3.46Å; V147-P235 HydrophobicContact CG2-CB 3.55Å; V147-P235 HydrophobicContact CG2-CG 4.35Å; I230-P235 WeakPolarHBondContact O-CD 3.45Å; I230-P235 WeakPolarHBondContact O-CG 3.31Å; P235-V238 PolarHBondContact O-N 2.99Å; P235-M239 HydrophobicContact CB-CE 4.36Å; P235-M239 WeakPolarHBondContact O-CB 3.46Å; P235-M239 WeakPolarHBondContact O-CE 3.45Å; P235-M239 VanDerWaalsContact O-CG 3.28Å; P235-M239 WeakPolarHBondContact O-CG 3.28Å; P235-M239 PolarHBondContact O-N 3.47Å; P235-F342 HydrophobicContact CB-CZ 4.38Å
236	G	94.3	Very high	93.6	Very high	1 Å²	1	41.5 Å²	41.5	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-58.9	-49.2	179.3	0	0	0	0	0	112.4	F232 F233 I234 M239 I240	F232-G236 WeakPolarHBondContact O-CA 3.49Å; F232-G236 PolarHBondContact O-N 3.4Å; F233-G236 PolarHBondContact O-N 3.08Å; I234-G236 VanDerWaalsContact C-N 3.34Å; I234-G236 PolarHBondContact O-N 3.03Å; G236-M239 PolarHBondContact O-N 3.5Å; G236-I240 WeakPolarHBondContact O-CB 3.47Å; G236-I240 VanDerWaalsContact O-CG1 3.22Å; G236-I240 WeakPolarHBondContact O-CG1 3.47Å; G236-I240 PolarHBondContact O-N 3.43Å
237	V	95.2	Very high	93.2	Very high	78 Å²	78	40 Å²	40	47%	0.473	22%	0.222	S	C	.	.	H	α-helix	trans	-62.1	-47.1	178.2	170.6	0	0	0	0	111	F233 I234 M239 I240 I241	F233-V237 WeakPolarHBondContact O-CB 3.44Å; F233-V237 VanDerWaalsContact O-CG2 3.31Å; F233-V237 WeakPolarHBondContact O-CG2 3.45Å; F233-V237 PolarHBondContact O-N 2.79Å; I234-V237 PolarHBondContact O-N 3.43Å; V237-M239 VanDerWaalsContact C-N 3.32Å; V237-M239 PolarHBondContact O-N 3.27Å; V237-I240 PolarHBondContact O-N 3.24Å; V237-I241 HydrophobicContact CG1-CD1 3.63Å; V237-I241 HydrophobicContact CG1-CG1 4.35Å; V237-I241 WeakPolarHBondContact O-CB 3.5Å; V237-I241 VanDerWaalsContact O-CG1 3.31Å; V237-I241 WeakPolarHBondContact O-CG1 3.37Å; V237-I241 PolarHBondContact O-N 3.09Å
238	V	95.4	Very high	92.8	Very high	51 Å²	51	48 Å²	48	31%	0.309	25%	0.252	S	S	.	.	H	α-helix	trans	-60.6	-43.6	178.6	174.6	0	0	0	0	110.9	V147 I151 I234 P235 A242	V147-V238 HydrophobicContact CG1-CB 4.32Å; V147-V238 HydrophobicContact CG1-CG1 3.72Å; I151-V238 HydrophobicContact CD1-CG1 4.2Å; I151-V238 HydrophobicContact CG1-CG1 4.24Å; I234-V238 HydrophobicContact CG2-CG2 4.49Å; I234-V238 VanDerWaalsContact O-CG2 3.3Å; I234-V238 WeakPolarHBondContact O-CG2 3.47Å; I234-V238 PolarHBondContact O-N 2.92Å; P235-V238 PolarHBondContact O-N 2.99Å; V238-A242 WeakPolarHBondContact O-CB 3.44Å; V238-A242 PolarHBondContact O-N 3.05Å
239	M	92.8	Very high	92.4	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-63.3	-48.3	176.5	-74.4	-171.6	-69.1	0	0	111.9	L146 V147 A150 P235 G236 V237 I241 A242 Y243 V339 F342	L146-M239 HydrophobicContact CB-SD 4.03Å; V147-M239 HydrophobicContact CG2-CG 4.32Å; A150-M239 HydrophobicContact CB-CG 4.15Å; P235-M239 HydrophobicContact CB-CE 4.36Å; P235-M239 WeakPolarHBondContact O-CB 3.46Å; P235-M239 WeakPolarHBondContact O-CE 3.45Å; P235-M239 VanDerWaalsContact O-CG 3.28Å; P235-M239 WeakPolarHBondContact O-CG 3.28Å; P235-M239 PolarHBondContact O-N 3.47Å; G236-M239 PolarHBondContact O-N 3.5Å; V237-M239 VanDerWaalsContact C-N 3.32Å; V237-M239 PolarHBondContact O-N 3.27Å; M239-I241 PolarHBondContact O-N 3.42Å; M239-A242 PolarHBondContact O-N 3.26Å; M239-Y243 HydrophobicContact CB-CD2 4.15Å; M239-Y243 HydrophobicContact CB-CE2 4.05Å; M239-Y243 HydrophobicContact CG-CE2 4.25Å; M239-Y243 WeakPolarHBondContact O-CB 3.21Å; M239-Y243 WeakPolarHBondContact O-CD2 3.31Å; M239-Y243 PolarHBondContact O-N 3.36Å; M239-V339 HydrophobicContact CB-CG2 4.23Å; M239-F342 HydrophobicContact CE-CB 4.36Å; M239-F342 HydrophobicContact CE-CD1 3.56Å; M239-F342 HydrophobicContact CE-CD2 4.22Å; M239-F342 HydrophobicContact CE-CE1 3.8Å; M239-F342 HydrophobicContact CE-CE2 4.42Å; M239-F342 HydrophobicContact CE-CG 3.78Å; M239-F342 HydrophobicContact CE-CZ 4.22Å
240	I	92.4	Very high	91.6	Very high	95 Å²	95	47 Å²	47	49%	0.487	25%	0.245	S	C	.	.	H	α-helix	trans	-58.5	-47.7	179.6	-71.7	165.5	0	0	0	110.6	G236 V237 G244 V339 F343	G236-I240 WeakPolarHBondContact O-CB 3.47Å; G236-I240 VanDerWaalsContact O-CG1 3.22Å; G236-I240 WeakPolarHBondContact O-CG1 3.47Å; G236-I240 PolarHBondContact O-N 3.43Å; V237-I240 PolarHBondContact O-N 3.24Å; I240-G244 PolarHBondContact O-N 3.26Å; I240-V339 HydrophobicContact CG1-CG1 4.3Å; I240-F343 HydrophobicContact CD1-CE2 3.86Å; I240-F343 HydrophobicContact CD1-CZ 3.66Å; I240-F343 HydrophobicContact CG1-CE2 4.17Å; I240-F343 HydrophobicContact CG1-CZ 4.36Å
241	I	93.4	Very high	91	Very high	98 Å²	98	51.8 Å²	51.8	50%	0.503	26%	0.262	S	S	.	.	H	α-helix	trans	-63.5	-50.3	178.9	-66.9	171	0	0	0	110.3	V237 M239 Y243 G244 L245	V237-I241 HydrophobicContact CG1-CD1 3.63Å; V237-I241 HydrophobicContact CG1-CG1 4.35Å; V237-I241 WeakPolarHBondContact O-CB 3.5Å; V237-I241 VanDerWaalsContact O-CG1 3.31Å; V237-I241 WeakPolarHBondContact O-CG1 3.37Å; V237-I241 PolarHBondContact O-N 3.09Å; M239-I241 PolarHBondContact O-N 3.42Å; I241-Y243 PolarHBondContact O-N 3.29Å; I241-G244 PolarHBondContact O-N 3.02Å; I241-L245 HydrophobicContact CG2-CD1 3.96Å; I241-L245 HydrophobicContact CG2-CG 4.39Å; I241-L245 VanDerWaalsContact O-CG 3.31Å; I241-L245 WeakPolarHBondContact O-CG 3.25Å; I241-L245 PolarHBondContact O-N 3.28Å
242	A	91.8	Very high	90.5	Very high	8 Å²	8	59.3 Å²	59.3	7%	0.066	29%	0.29	C	S	.	.	H	α-helix	trans	-57.8	-48.7	-178.5	0	0	0	0	0	111.6	A150 V238 M239 L245 I246	A150-A242 HydrophobicContact CB-CB 4.19Å; V238-A242 WeakPolarHBondContact O-CB 3.44Å; V238-A242 PolarHBondContact O-N 3.05Å; M239-A242 PolarHBondContact O-N 3.26Å; A242-L245 PolarHBondContact O-N 3.05Å; A242-I246 WeakPolarHBondContact O-CD1 3.19Å; A242-I246 WeakPolarHBondContact O-CG1 3.49Å; A242-I246 PolarHBondContact O-N 2.73Å
243	Y	88.4	Confident	89.8	Confident	3 Å²	3	60.3 Å²	60.3	1%	0.012	30%	0.303	C	S	.	.	H	α-helix	trans	-74.7	-29.4	-179.5	-63.2	-54.6	0	0	0	113.5	A150 M239 I241 I246 S247 L335 V339	A150-Y243 WeakPolarHBondContact CA-OH 3.39Å; A150-Y243 HydrophobicContact CB-CD2 4.48Å; A150-Y243 HydrophobicContact CB-CE1 4.02Å; A150-Y243 HydrophobicContact CB-CE2 3.71Å; A150-Y243 VanDerWaalsContact CB-CZ 3.44Å; A150-Y243 WeakPolarHBondContact CB-OH 3.14Å; M239-Y243 HydrophobicContact CB-CD2 4.15Å; M239-Y243 HydrophobicContact CB-CE2 4.05Å; M239-Y243 HydrophobicContact CG-CE2 4.25Å; M239-Y243 WeakPolarHBondContact O-CB 3.21Å; M239-Y243 WeakPolarHBondContact O-CD2 3.31Å; M239-Y243 PolarHBondContact O-N 3.36Å; I241-Y243 PolarHBondContact O-N 3.29Å; Y243-I246 HydrophobicContact CD1-CD1 3.66Å; Y243-I246 HydrophobicContact CE1-CD1 4.14Å; Y243-I246 PolarHBondContact O-N 2.95Å; Y243-S247 WeakPolarHBondContact O-CB 3.32Å; Y243-S247 PolarHBondContact O-N 3.38Å; Y243-S247 PolarHBondContact O-OG 2.65Å; Y243-L335 HydrophobicContact CD1-CB 3.85Å; Y243-L335 HydrophobicContact CD1-CD1 4.31Å; Y243-L335 HydrophobicContact CE1-CB 3.52Å; Y243-L335 HydrophobicContact CE1-CD1 3.8Å; Y243-L335 HydrophobicContact CE1-CD2 3.9Å; Y243-L335 HydrophobicContact CE1-CG 3.91Å; Y243-V339 HydrophobicContact CD2-CG2 3.18Å; Y243-V339 HydrophobicContact CE2-CG2 3.29Å; Y243-V339 HydrophobicContact CG-CG2 4.27Å
244	G	89.7	Confident	88.9	Confident	41 Å²	41	55.7 Å²	55.7	42%	0.423	28%	0.283	S	S	.	.	H	α-helix	trans	-61.6	-47.2	169.9	0	0	0	0	0	111.8	I240 I241 S247 R248	I240-G244 PolarHBondContact O-N 3.26Å; I241-G244 PolarHBondContact O-N 3.02Å; G244-S247 PolarHBondContact O-N 2.97Å; G244-R248 PolarHBondContact O-N 2.94Å
245	L	90.6	Very high	88.1	Confident	54 Å²	54	55.4 Å²	55.4	28%	0.283	28%	0.28	S	S	.	.	H	α-helix	trans	-64.3	-42.3	176	-67.4	175.1	0	0	0	112.2	Y154 I241 A242 S247 R248 E249	Y154-L245 HydrophobicContact CD2-CB 4.03Å; Y154-L245 HydrophobicContact CD2-CD1 4.34Å; Y154-L245 HydrophobicContact CE2-CB 3.75Å; Y154-L245 HydrophobicContact CE2-CD1 3.65Å; Y154-L245 HydrophobicContact CE2-CG 4.36Å; I241-L245 HydrophobicContact CG2-CD1 3.96Å; I241-L245 HydrophobicContact CG2-CG 4.39Å; I241-L245 VanDerWaalsContact O-CG 3.31Å; I241-L245 WeakPolarHBondContact O-CG 3.25Å; I241-L245 PolarHBondContact O-N 3.28Å; A242-L245 PolarHBondContact O-N 3.05Å; L245-S247 VanDerWaalsContact C-N 3.31Å; L245-S247 PolarHBondContact O-N 3.31Å; L245-R248 PolarHBondContact O-N 3.36Å; L245-E249 WeakPolarHBondContact O-CB 3.31Å; L245-E249 PolarHBondContact O-N 2.74Å
246	I	88	Confident	87.4	Confident	0 Å²	0	61.5 Å²	61.5	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-58.9	-44.4	174.2	-70.4	160.9	0	0	0	110.8	R153 Y154 I157 A242 Y243 E249 L250 I332	R153-I246 HydrophobicContact CB-CD1 4.06Å; Y154-I246 HydrophobicContact CD2-CG1 4.26Å; I157-I246 HydrophobicContact CD1-CG2 3.84Å; I157-I246 HydrophobicContact CG2-CG2 4.37Å; A242-I246 WeakPolarHBondContact O-CD1 3.19Å; A242-I246 WeakPolarHBondContact O-CG1 3.49Å; A242-I246 PolarHBondContact O-N 2.73Å; Y243-I246 HydrophobicContact CD1-CD1 3.66Å; Y243-I246 HydrophobicContact CE1-CD1 4.14Å; Y243-I246 PolarHBondContact O-N 2.95Å; I246-E249 PolarHBondContact O-N 3.24Å; I246-L250 WeakPolarHBondContact O-CB 3.48Å; I246-L250 PolarHBondContact O-N 3.01Å; I246-I332 HydrophobicContact CG2-CD1 3.51Å; I246-I332 HydrophobicContact CG2-CG1 3.63Å; I246-I332 HydrophobicContact CG2-CG2 4.43Å
247	S	86.1	Confident	86.5	Confident	41 Å²	41	64.1 Å²	64.1	29%	0.287	32%	0.318	S	S	.	.	H	α-helix	trans	-64.8	-42.4	-179.1	-61.5	0	0	0	0	111.5	Y243 G244 L245 L250 Y251	Y243-S247 WeakPolarHBondContact O-CB 3.32Å; Y243-S247 PolarHBondContact O-N 3.38Å; Y243-S247 PolarHBondContact O-OG 2.65Å; G244-S247 PolarHBondContact O-N 2.97Å; L245-S247 VanDerWaalsContact C-N 3.31Å; L245-S247 PolarHBondContact O-N 3.31Å; S247-L250 PolarHBondContact O-N 2.81Å; S247-Y251 WeakPolarHBondContact O-CB 3.48Å; S247-Y251 PolarHBondContact O-N 3.46Å
248	R	87.3	Confident	85.5	Confident	177 Å²	177	64.6 Å²	64.6	67%	0.668	32%	0.318	S	S	*	.	H	α-helix	trans	-63.1	-47.9	175.9	-171.4	178	72.9	172.2	2.4	112	G244 L245 L250 Y251 R252	G244-R248 PolarHBondContact O-N 2.94Å; L245-R248 PolarHBondContact O-N 3.36Å; R248-L250 VanDerWaalsContact C-N 3.31Å; R248-L250 PolarHBondContact O-N 2.99Å; R248-Y251 PolarHBondContact O-N 3.24Å; R248-R252 PolarHBondContact O-N 3.13Å
249	E	85.7	Confident	84.5	Confident	58 Å²	58	64.4 Å²	64.4	27%	0.271	32%	0.319	S	S	.	.	H	α-helix	trans	-63.2	-41.6	-179.7	-171.8	57.7	-146.7	0	0	111.3	L245 I246 R252 G253	L245-E249 WeakPolarHBondContact O-CB 3.31Å; L245-E249 PolarHBondContact O-N 2.74Å; I246-E249 PolarHBondContact O-N 3.24Å; E249-R252 VanDerWaalsContact CD-NH2 3.27Å; E249-R252 PolarHBondContact O-N 3.12Å; E249-R252 IonicContact OE1-CZ 3.47Å; E249-R252 IonicContact OE1-NE 3.61Å; E249-R252 IonicContact OE1-NH2 2.98Å; E249-R252 PolarHBondContact OE1-NH2 2.67Å; E249-R252 IonicContact OE2-CZ 2.76Å; E249-R252 IonicContact OE2-NE 2.77Å; E249-R252 IonicContact OE2-NH2 3.58Å; E249-R252 PolarHBondContact OE2-NH2 3.14Å; E249-G253 PolarHBondContact O-N 3.24Å
250	L	80	Confident	83.7	Confident	21 Å²	21	69.2 Å²	69.2	11%	0.11	34%	0.342	C	S	.	.	H	α-helix	trans	-62.1	-50.2	174.7	-169.3	82	0	0	0	110.5	I246 S247 R248 R252 G253 I254 L325 K328 R329 I332	I246-L250 WeakPolarHBondContact O-CB 3.48Å; I246-L250 PolarHBondContact O-N 3.01Å; S247-L250 PolarHBondContact O-N 2.81Å; R248-L250 VanDerWaalsContact C-N 3.31Å; R248-L250 PolarHBondContact O-N 2.99Å; L250-R252 VanDerWaalsContact C-N 3.26Å; L250-R252 PolarHBondContact O-N 3.44Å; L250-G253 PolarHBondContact O-N 3.48Å; L250-G253 VanDerWaalsContact O-N 3.07Å; L250-I254 HydrophobicContact CD2-CD1 4.22Å; L250-I254 HydrophobicContact CG-CD1 4.13Å; L250-I254 VanDerWaalsContact O-CG1 3.27Å; L250-I254 WeakPolarHBondContact O-CG1 3.34Å; L250-I254 PolarHBondContact O-N 3.22Å; L250-L325 HydrophobicContact CD1-CD1 4.12Å; L250-K328 HydrophobicContact CD1-CB 3.84Å; L250-K328 HydrophobicContact CD1-CD 4.3Å; L250-R329 HydrophobicContact CD2-CB 4.42Å; L250-R329 HydrophobicContact CD2-CG 3.57Å; L250-I332 HydrophobicContact CB-CD1 3.83Å; L250-I332 HydrophobicContact CD1-CD1 3.79Å; L250-I332 HydrophobicContact CD2-CD1 3.4Å; L250-I332 VanDerWaalsContact CD2-CD1 3.4Å; L250-I332 HydrophobicContact CG-CD1 3.84Å
251	Y	82.4	Confident	82.7	Confident	145 Å²	145	67.2 Å²	67.2	57%	0.569	33%	0.332	S	S	*	.	H	α-helix	trans	-57.2	-42.2	-178.8	-170.9	-94.5	0	0	0	111.8	S247 R248 I254 Q255	S247-Y251 WeakPolarHBondContact O-CB 3.48Å; S247-Y251 PolarHBondContact O-N 3.46Å; R248-Y251 PolarHBondContact O-N 3.24Å; Y251-I254 PolarHBondContact O-N 2.78Å; Y251-Q255 HydrophobicContact CD1-CG 4.02Å; Y251-Q255 HydrophobicContact CE1-CG 3.64Å; Y251-Q255 WeakPolarHBondContact O-CG 3.48Å; Y251-Q255 PolarHBondContact O-N 3Å; Y251-Q255 PolarHBondContact OH-NE2 3.25Å
252	R	84.4	Confident	81.7	Confident	160 Å²	160	70.4 Å²	70.4	60%	0.604	34%	0.342	S	S	*	.	H	α-helix	trans	-61	-44.9	174.5	-169.7	177	69.5	163.8	2.7	112.3	R248 E249 L250 I254 Q255 F256	R248-R252 PolarHBondContact O-N 3.13Å; E249-R252 VanDerWaalsContact CD-NH2 3.27Å; E249-R252 PolarHBondContact O-N 3.12Å; E249-R252 IonicContact OE1-CZ 3.47Å; E249-R252 IonicContact OE1-NE 3.61Å; E249-R252 IonicContact OE1-NH2 2.98Å; E249-R252 PolarHBondContact OE1-NH2 2.67Å; E249-R252 IonicContact OE2-CZ 2.76Å; E249-R252 IonicContact OE2-NE 2.77Å; E249-R252 IonicContact OE2-NH2 3.58Å; E249-R252 PolarHBondContact OE2-NH2 3.14Å; L250-R252 VanDerWaalsContact C-N 3.26Å; L250-R252 PolarHBondContact O-N 3.44Å; R252-I254 VanDerWaalsContact C-N 3.26Å; R252-I254 PolarHBondContact O-N 3.07Å; R252-Q255 PolarHBondContact O-N 2.87Å; R252-F256 PolarHBondContact O-N 3.17Å
253	G	80.4	Confident	80.7	Confident	32 Å²	32	76.4 Å²	76.4	33%	0.33	37%	0.369	S	S	.	.	H	α-helix	trans	-61.3	-33.3	176.4	0	0	0	0	0	113.3	E249 L250 E257	E249-G253 PolarHBondContact O-N 3.24Å; L250-G253 PolarHBondContact O-N 3.48Å; L250-G253 VanDerWaalsContact O-N 3.07Å; G253-E257 PolarHBondContact O-N 2.98Å; G253-E257 VanDerWaalsContact O-N 3.16Å
254	I	76.8	Confident	79.7	Confident	10 Å²	10	78.6 Å²	78.6	5%	0.051	38%	0.382	C	S	.	.	H	α-helix	trans	-74.6	-43.2	177.7	-59.3	-174.5	0	0	0	111.6	L250 Y251 R252 F256 E257 L258 L325 R329	L250-I254 HydrophobicContact CD2-CD1 4.22Å; L250-I254 HydrophobicContact CG-CD1 4.13Å; L250-I254 VanDerWaalsContact O-CG1 3.27Å; L250-I254 WeakPolarHBondContact O-CG1 3.34Å; L250-I254 PolarHBondContact O-N 3.22Å; Y251-I254 PolarHBondContact O-N 2.78Å; R252-I254 VanDerWaalsContact C-N 3.26Å; R252-I254 PolarHBondContact O-N 3.07Å; I254-F256 PolarHBondContact O-N 2.73Å; I254-E257 PolarHBondContact O-N 3.43Å; I254-L258 HydrophobicContact CG2-CD1 3.81Å; I254-L258 HydrophobicContact CG2-CG 4.39Å; I254-L258 WeakPolarHBondContact O-CB 3.24Å; I254-L258 WeakPolarHBondContact O-CG 3.09Å; I254-L258 PolarHBondContact O-N 3.07Å; I254-L325 HydrophobicContact CB-CD2 4.16Å; I254-L325 HydrophobicContact CD1-CD1 3.82Å; I254-L325 HydrophobicContact CD1-CD2 3.91Å; I254-L325 HydrophobicContact CD1-CG 3.89Å; I254-L325 HydrophobicContact CG1-CD1 3.42Å; I254-L325 VanDerWaalsContact CG1-CD1 3.42Å; I254-L325 HydrophobicContact CG1-CD2 3.49Å; I254-L325 VanDerWaalsContact CG1-CD2 3.49Å; I254-L325 HydrophobicContact CG1-CG 3.76Å; I254-L325 HydrophobicContact CG2-CD2 4.03Å; I254-R329 HydrophobicContact CD1-CG 4.04Å
255	Q	79.8	Confident	78.5	Confident	87 Å²	87	79 Å²	79	41%	0.407	38%	0.381	S	S	.	.	H	α-helix	trans	-59	-39.9	175.2	-75.9	-67.6	-7.8	0	0	110.8	Y251 R252 L258 S259	Y251-Q255 HydrophobicContact CD1-CG 4.02Å; Y251-Q255 HydrophobicContact CE1-CG 3.64Å; Y251-Q255 WeakPolarHBondContact O-CG 3.48Å; Y251-Q255 PolarHBondContact O-N 3Å; Y251-Q255 PolarHBondContact OH-NE2 3.25Å; R252-Q255 PolarHBondContact O-N 2.87Å; Q255-L258 PolarHBondContact O-N 3.37Å; Q255-S259 PolarHBondContact O-N 3.44Å; Q255-S259 PolarHBondContact O-OG 3.08Å
256	F	79.6	Confident	77	Confident	132 Å²	132	78.5 Å²	78.5	58%	0.579	39%	0.39	S	S	*	.	H	α-helix	trans	-65.1	-42.1	175.8	-173.3	-96	0	0	0	113.5	R252 I254 S259 Q260	R252-F256 PolarHBondContact O-N 3.17Å; I254-F256 PolarHBondContact O-N 2.73Å; F256-S259 WeakPolarHBondContact CA-OG 3.24Å; F256-S259 PolarHBondContact O-N 3.48Å; F256-S259 PolarHBondContact O-OG 3.15Å; F256-Q260 WeakPolarHBondContact O-CB 3.27Å; F256-Q260 PolarHBondContact O-N 3.47Å
257	E	76.3	Confident	75.5	Confident	55 Å²	55	86 Å²	86	26%	0.257	42%	0.424	S	S	.	.	H	α-helix	trans	-67.8	-36.2	174.8	-72.6	-155.6	-162.9	0	0	111.9	G253 I254 Q260 N261 S321	G253-E257 PolarHBondContact O-N 2.98Å; G253-E257 VanDerWaalsContact O-N 3.16Å; I254-E257 PolarHBondContact O-N 3.43Å; E257-Q260 PolarHBondContact O-N 3.31Å; E257-N261 WeakPolarHBondContact O-CB 3.47Å; E257-N261 PolarHBondContact O-N 3.36Å; E257-S321 VanDerWaalsContact OE2-CB 3.29Å; E257-S321 WeakPolarHBondContact OE2-CB 3.32Å; E257-S321 PolarHBondContact OE2-OG 3.26Å
258	L	74.2	Confident	74	Confident	88 Å²	88	89 Å²	89	46%	0.461	43%	0.433	S	S	.	.	H	α-helix	trans	-66.5	-39.1	174.9	-77.8	163.9	0	0	0	112.5	I254 Q255 N261 K262	I254-L258 HydrophobicContact CG2-CD1 3.81Å; I254-L258 HydrophobicContact CG2-CG 4.39Å; I254-L258 WeakPolarHBondContact O-CB 3.24Å; I254-L258 WeakPolarHBondContact O-CG 3.09Å; I254-L258 PolarHBondContact O-N 3.07Å; Q255-L258 PolarHBondContact O-N 3.37Å; L258-N261 PolarHBondContact O-N 2.88Å; L258-K262 WeakPolarHBondContact O-CG 3.28Å; L258-K262 PolarHBondContact O-N 2.95Å
259	S	75.5	Confident	72.4	Confident	48 Å²	48	87.4 Å²	87.4	34%	0.336	44%	0.437	S	S	.	.	H	α-helix	trans	-66.8	-44.3	175.7	58.6	0	0	0	0	111.2	Q255 F256 N261 K262 E263	Q255-S259 PolarHBondContact O-N 3.44Å; Q255-S259 PolarHBondContact O-OG 3.08Å; F256-S259 WeakPolarHBondContact CA-OG 3.24Å; F256-S259 PolarHBondContact O-N 3.48Å; F256-S259 PolarHBondContact O-OG 3.15Å; S259-N261 VanDerWaalsContact C-N 3.34Å; S259-N261 PolarHBondContact O-N 3.37Å; S259-K262 WeakPolarHBondContact O-CB 3.35Å; S259-K262 PolarHBondContact O-N 2.84Å; S259-K262 VanDerWaalsContact O-N 3.15Å; S259-E263 PolarHBondContact O-N 3.02Å
260	Q	75.5	Confident	70.6	Confident	101 Å²	101	87.5 Å²	87.5	47%	0.472	45%	0.454	S	S	.	.	H	α-helix	trans	-62.1	-41.4	175.7	-174.8	166.3	73.3	0	0	111.7	F256 E257 K262 E263 T264	F256-Q260 WeakPolarHBondContact O-CB 3.27Å; F256-Q260 PolarHBondContact O-N 3.47Å; E257-Q260 PolarHBondContact O-N 3.31Å; Q260-K262 VanDerWaalsContact C-N 3.32Å; Q260-K262 PolarHBondContact O-N 3.46Å; Q260-E263 PolarHBondContact O-N 3.11Å; Q260-T264 PolarHBondContact O-N 3.34Å; Q260-T264 PolarHBondContact O-OG1 3.14Å
261	N	70.9	Confident	69	Low	53 Å²	53	93.2 Å²	93.2	28%	0.283	49%	0.489	S	S	.	.	H	α-helix	trans	-63.5	-35.6	175.4	-79.2	-10	0	0	0	112.5	E257 L258 S259 A265	E257-N261 WeakPolarHBondContact O-CB 3.47Å; E257-N261 PolarHBondContact O-N 3.36Å; L258-N261 PolarHBondContact O-N 2.88Å; S259-N261 VanDerWaalsContact C-N 3.34Å; S259-N261 PolarHBondContact O-N 3.37Å; N261-A265 VanDerWaalsContact O-CB 3.24Å; N261-A265 WeakPolarHBondContact O-CB 3.4Å; N261-A265 PolarHBondContact O-N 3.2Å
262	K	71.9	Confident	67.4	Low	164 Å²	164	89.8 Å²	89.8	71%	0.713	50%	0.498	S	S	*	.	H	α-helix	trans	-67.3	-43.5	174.6	-79.3	-178	177.2	-176.3	0	112.4	L258 S259 Q260 A265 G266	L258-K262 WeakPolarHBondContact O-CG 3.28Å; L258-K262 PolarHBondContact O-N 2.95Å; S259-K262 WeakPolarHBondContact O-CB 3.35Å; S259-K262 PolarHBondContact O-N 2.84Å; S259-K262 VanDerWaalsContact O-N 3.15Å; Q260-K262 VanDerWaalsContact C-N 3.32Å; Q260-K262 PolarHBondContact O-N 3.46Å; K262-A265 PolarHBondContact O-N 3.07Å; K262-G266 PolarHBondContact O-N 3.33Å
263	E	71.5	Confident	65.2	Low	135 Å²	135	92.4 Å²	92.4	63%	0.631	51%	0.508	S	S	*	.	H	α-helix	trans	-62.6	-46.6	176	-72.1	171.7	-177	0	0	111.3	S259 Q260 A265 G266 Q267	S259-E263 PolarHBondContact O-N 3.02Å; Q260-E263 PolarHBondContact O-N 3.11Å; E263-A265 VanDerWaalsContact C-N 3.32Å; E263-A265 PolarHBondContact O-N 3.21Å; E263-G266 PolarHBondContact O-N 3.23Å; E263-Q267 PolarHBondContact O-N 3.42Å
264	T	66.3	Low	63.3	Low	48 Å²	48	96.1 Å²	96.1	29%	0.294	54%	0.536	S	S	.	.	H	α-helix	trans	-65.3	-34.9	179.1	-34.7	0	0	0	0	112.2	Q260 K268	Q260-T264 PolarHBondContact O-N 3.34Å; Q260-T264 PolarHBondContact O-OG1 3.14Å; T264-K268 PolarHBondContact O-N 3.05Å
265	A	64.6	Low	61.4	Low	49 Å²	49	100.6 Å²	100.6	41%	0.405	56%	0.563	S	S	.	*	H	α-helix	trans	-73.4	-37.6	175	0	0	0	0	0	112.5	N261 K262 E263 Q267 K268 N269	N261-A265 VanDerWaalsContact O-CB 3.24Å; N261-A265 WeakPolarHBondContact O-CB 3.4Å; N261-A265 PolarHBondContact O-N 3.2Å; K262-A265 PolarHBondContact O-N 3.07Å; E263-A265 VanDerWaalsContact C-N 3.32Å; E263-A265 PolarHBondContact O-N 3.21Å; A265-Q267 VanDerWaalsContact C-N 3.33Å; A265-Q267 PolarHBondContact O-N 2.97Å; A265-K268 PolarHBondContact O-N 3.32Å; A265-N269 PolarHBondContact O-N 3.26Å; A265-N269 VanDerWaalsContact O-N 3.16Å
266	G	59.5	Low	59.4	Low	44 Å²	44	101.6 Å²	101.6	45%	0.454	59%	0.586	S	S	.	*	H	α-helix	trans	-62.2	-39.9	173.9	0	0	0	0	0	112.3	K262 E263 N269 G270	K262-G266 PolarHBondContact O-N 3.33Å; E263-G266 PolarHBondContact O-N 3.23Å; G266-N269 PolarHBondContact O-N 2.82Å; G266-G270 PolarHBondContact O-N 2.94Å; G266-G270 VanDerWaalsContact O-N 3.11Å
267	Q	57	Low	57.2	Low	157 Å²	157	98.7 Å²	98.7	73%	0.734	59%	0.594	S	S	*	*	H	α-helix	trans	-73.4	-28.4	179.3	-159.4	150.1	12.9	0	0	113.4	E263 A265	E263-Q267 PolarHBondContact O-N 3.42Å; A265-Q267 VanDerWaalsContact C-N 3.33Å; A265-Q267 PolarHBondContact O-N 2.97Å
268	K	54.6	Low	55.6	Low	105 Å²	105	101.8 Å²	101.8	46%	0.457	62%	0.619	S	S	.	*	H	α-helix	trans	-73.6	-26.5	171.2	-84.2	178	-177.1	172.8	0	113.7	T264 A265 N311 E314	T264-K268 PolarHBondContact O-N 3.05Å; A265-K268 PolarHBondContact O-N 3.32Å; K268-N311 VanDerWaalsContact CE-OD1 3.3Å; K268-N311 WeakPolarHBondContact CE-OD1 3.36Å; K268-N311 PolarHBondContact NZ-OD1 3.26Å; K268-E314 IonicContact NZ-OE2 3.57Å; K268-E314 PolarHBondContact NZ-OE2 3.49Å
269	N	52.7	Low	53.9	Low	144 Å²	144	102.1 Å²	102.1	77%	0.77	63%	0.628	S	S	*	*	S	Bend	trans	-91.5	-4.1	176.6	-65.1	-12.3	0	0	0	112.9	A265 G266	A265-N269 PolarHBondContact O-N 3.26Å; A265-N269 VanDerWaalsContact O-N 3.16Å; G266-N269 PolarHBondContact O-N 2.82Å
270	G	48	Very low	51.9	Low	60 Å²	60	107.1 Å²	107.1	62%	0.619	65%	0.651	S	S	*	*			trans	-106.1	29.8	-175.8	0	0	0	0	0	115.3	G266	G266-G270 PolarHBondContact O-N 2.94Å; G266-G270 VanDerWaalsContact O-N 3.11Å
271	V	47.4	Very low	50.1	Low	140 Å²	140	109.8 Å²	109.8	85%	0.848	67%	0.669	S	S	*	*			trans	-102.4	99.3	167.3	-179.2	0	0	0	0	108.4
272	G	48.4	Very low	48.2	Very low	73 Å²	73	114.7 Å²	114.7	75%	0.753	70%	0.695	S	S	*	*			trans	155.5	48.7	171.1	0	0	0	0	0	115.8
273	R	37.7	Very low	46.5	Very low	216 Å²	216	114.6 Å²	114.6	82%	0.815	70%	0.702	S	S	*	*			trans	-158.2	79.5	153.4	-151.8	145.7	167.4	153.6	-5.3	112.3	T275	R273-T275 HydrophobicContact CG-CG2 3.74Å; R273-T275 PolarHBondContact O-N 2.98Å
274	A	40.3	Very low	44.8	Very low	110 Å²	110	111.8 Å²	111.8	91%	0.909	71%	0.71	S	S	*	*			trans	-75.7	95.3	151.2	0	0	0	0	0	106.7
275	T	37.2	Very low	43.3	Very low	103 Å²	103	114.7 Å²	114.7	63%	0.632	73%	0.731	S	S	*	*			trans	-91.6	107.7	161.8	34.9	0	0	0	0	107.7	R273	R273-T275 HydrophobicContact CG-CG2 3.74Å; R273-T275 PolarHBondContact O-N 2.98Å
276	A	39.1	Very low	41.8	Very low	108 Å²	108	122.3 Å²	122.3	89%	0.893	75%	0.751	S	S	*	*			trans	-66	139.9	162.6	0	0	0	0	0	110
277	G	31.9	Very low	40.5	Very low	71 Å²	71	126.6 Å²	126.6	73%	0.732	76%	0.762	S	S	*	*			trans	166.9	143.7	170	0	0	0	0	0	111.3
278	P	42.5	Very low	39.2	Very low	121 Å²	121	128 Å²	128	79%	0.786	77%	0.768	S	S	*	*			trans	-105.7	163.6	-130.6	38.6	-32.9	0	0	0	115.4
279	S	39.3	Very low	38.1	Very low	95 Å²	95	129.5 Å²	129.5	66%	0.664	79%	0.786	S	S	*	*			trans	34.2	117.9	150.5	57.6	0	0	0	0	119.4
280	D	32.7	Very low	37.1	Very low	153 Å²	153	127.2 Å²	127.2	82%	0.818	78%	0.782	S	S	*	*				-178.8	159.2	112.9	-85.1	-15.1	0	0	0	110.9
281	D	38	Very low	36.3	Very low	157 Å²	157	134.3 Å²	134.3	84%	0.84	80%	0.795	S	S	*	*			trans	-58.1	157.8	-160.1	-58.8	-58.5	0	0	0	118.2
282	D	32.4	Very low	35.4	Very low	156 Å²	156	136.8 Å²	136.8	83%	0.834	80%	0.795	S	S	*	*				143.3	146.3	127.8	-159.7	33.8	0	0	0	115.2
283	D	36.3	Very low	34.7	Very low	161 Å²	161	139.1 Å²	139.1	86%	0.861	80%	0.796	S	S	*	*			trans	-69.9	153.9	-153.5	-78.5	-45.4	0	0	0	118.5
284	G	35	Very low	34.3	Very low	77 Å²	77	134.4 Å²	134.4	79%	0.794	80%	0.797	S	S	*	*			trans	176.2	83.5	167.8	0	0	0	0	0	116.6
285	C	35.4	Very low	33.8	Very low	109 Å²	109	137.9 Å²	137.9	74%	0.736	79%	0.792	S	S	*	*			trans	-46.9	136.7	175.2	-175.3	0	0	0	0	115.8
286	Y	32.1	Very low	33.6	Very low	208 Å²	208	137.2 Å²	137.2	82%	0.816	80%	0.797	S	S	*	*				-173.5	115.2	119.3	-100.8	-75.7	0	0	0	112.6
287	I	33.4	Very low	33.4	Very low	134 Å²	134	137.8 Å²	137.8	69%	0.687	79%	0.789	S	S	*	*			trans	44.7	97.4	153.9	-56.5	176.3	0	0	0	118.2	V289	I287-V289 HydrophobicContact CG2-CG2 4.39Å
288	Q	28.8	Very low	33.7	Very low	186 Å²	186	143.1 Å²	143.1	87%	0.869	80%	0.795	S	S	*	*			trans	-76.6	122.5	154.5	-76.9	-160.7	-6.9	0	0	110.9
289	V	32.3	Very low	33	Very low	138 Å²	138	145 Å²	145	84%	0.836	80%	0.798	S	S	*	*			trans	-90.5	109.2	154.7	176.3	0	0	0	0	107.7	I287 K291	I287-V289 HydrophobicContact CG2-CG2 4.39Å; V289-K291 PolarHBondContact O-N 3.08Å
290	S	30.5	Very low	33.5	Very low	96 Å²	96	145.4 Å²	145.4	67%	0.671	80%	0.797	S	S	*	*			trans	-62.5	124.8	-179	-157	0	0	0	0	111.9
291	K	31.9	Very low	33.8	Very low	208 Å²	208	144.3 Å²	144.3	90%	0.904	80%	0.796	S	S	*	*			trans	-117.7	104.7	151.1	-102.9	-175.5	178.2	177.7	0	107.5	V289	V289-K291 PolarHBondContact O-N 3.08Å
292	K	28.3	Very low	33.8	Very low	192 Å²	192	143.4 Å²	143.4	84%	0.835	79%	0.791	S	S	*	*			trans	-59.7	138.4	175.3	-137.2	173.1	-174	176.4	0	110
293	P	34.6	Very low	34.2	Very low	122 Å²	122	140.9 Å²	140.9	79%	0.792	79%	0.786	S	S	*	*			trans	-85.6	138.1	171.7	34.1	-29.3	0	0	0	109.1
294	S	29.2	Very low	34.5	Very low	118 Å²	118	137.4 Å²	137.4	83%	0.825	77%	0.774	S	S	*	*			trans	-118.1	103	165.9	44.5	0	0	0	0	109.1
295	F	29.7	Very low	34.9	Very low	183 Å²	183	136.5 Å²	136.5	80%	0.803	76%	0.756	S	S	*	*			trans	64.4	96	144.8	-135.3	-104.2	0	0	0	117.6	V297	F295-V297 HydrophobicContact CD1-CG2 3.84Å; F295-V297 HydrophobicContact CE1-CG2 3.68Å
296	A	32.8	Very low	35.6	Very low	89 Å²	89	135.6 Å²	135.6	74%	0.736	75%	0.747	S	S	*	*			trans	-73.9	120.1	154.9	0	0	0	0	0	108.9
297	V	33.6	Very low	36.5	Very low	120 Å²	120	129.6 Å²	129.6	73%	0.727	73%	0.732	S	S	*	*			trans	-103.5	106.9	142.4	177.2	0	0	0	0	104.2	F295	F295-V297 HydrophobicContact CD1-CG2 3.84Å; F295-V297 HydrophobicContact CE1-CG2 3.68Å
298	E	38.5	Very low	37.4	Very low	182 Å²	182	126.9 Å²	126.9	85%	0.85	72%	0.722	S	S	*	*			trans	-68.3	131	172.2	-75.8	-174.4	140.2	0	0	109.6
299	L	28.4	Very low	38.8	Very low	162 Å²	162	123.7 Å²	123.7	85%	0.848	71%	0.709	S	S	*	*			trans	-127.2	125.2	154.7	-158	73.9	0	0	0	107.1
300	P	50.2	Low	40	Very low	102 Å²	102	122.5 Å²	122.5	66%	0.662	70%	0.697	S	S	*	*			trans	-78.3	158.6	-172	31	-32.6	0	0	0	111
301	T	38.4	Very low	41.2	Very low	130 Å²	130	119.8 Å²	119.8	80%	0.798	68%	0.675	S	S	*	*	S	Bend	trans	92.8	79.1	169.6	72.5	0	0	0	0	117.7
302	L	38.6	Very low	42.4	Very low	139 Å²	139	117.1 Å²	117.1	73%	0.728	66%	0.664	S	S	*	*			trans	178.6	44.2	142.8	-101.4	145.8	0	0	0	112.9
303	S	39.8	Very low	43.8	Very low	103 Å²	103	110.8 Å²	110.8	72%	0.72	65%	0.647	S	S	*	*	H	α-helix	trans	-87	-4.3	-177.4	64.6	0	0	0	0	115.5	T307	S303-T307 PolarHBondContact O-OG1 3.05Å
304	S	43.9	Very low	44.9	Very low	88 Å²	88	108.7 Å²	108.7	62%	0.615	63%	0.627	S	S	*	*	H	α-helix	trans	-78.6	-38.7	177.4	173	0	0	0	0	112.6	T308	S304-T308 PolarHBondContact O-N 3.21Å; S304-T308 PolarHBondContact O-OG1 3.23Å
305	S	43.1	Very low	46.2	Very low	58 Å²	58	110.3 Å²	110.3	41%	0.406	62%	0.615	S	S	.	*	H	α-helix	trans	-73.7	-38.2	-171.8	-55.6	0	0	0	0	113.3	T308 I309	S305-T308 PolarHBondContact O-N 3.32Å; S305-I309 VanDerWaalsContact O-CG1 3.28Å; S305-I309 WeakPolarHBondContact O-CG1 3.41Å; S305-I309 PolarHBondContact O-N 2.89Å
306	T	49.2	Very low	47.3	Very low	90 Å²	90	104 Å²	104	55%	0.552	60%	0.597	S	S	*	*	H	α-helix	trans	-68.1	-42.2	-178.1	-46.4	0	0	0	0	111.8	T308 I309 L310	T306-T308 VanDerWaalsContact C-N 3.31Å; T306-T308 PolarHBondContact O-N 3.34Å; T306-I309 PolarHBondContact O-N 2.89Å; T306-L310 WeakPolarHBondContact O-CB 3.01Å; T306-L310 PolarHBondContact O-N 3.21Å
307	T	51.7	Low	48.5	Very low	81 Å²	81	109.7 Å²	109.7	50%	0.497	60%	0.599	S	S	.	*	H	α-helix	trans	-65.8	-35.1	177	-36.8	0	0	0	0	111.4	S303 N311	S303-T307 PolarHBondContact O-OG1 3.05Å; T307-N311 WeakPolarHBondContact O-CB 3.26Å; T307-N311 PolarHBondContact O-N 3.1Å; T307-N311 PolarHBondContact O-ND2 3.35Å
308	T	52.3	Low	49.6	Very low	78 Å²	78	105.6 Å²	105.6	48%	0.479	58%	0.576	S	S	.	*	H	α-helix	trans	-71.8	-38.1	177.3	-47	0	0	0	0	111.8	S304 S305 T306 K312	S304-T308 PolarHBondContact O-N 3.21Å; S304-T308 PolarHBondContact O-OG1 3.23Å; S305-T308 PolarHBondContact O-N 3.32Å; T306-T308 VanDerWaalsContact C-N 3.31Å; T306-T308 PolarHBondContact O-N 3.34Å; T308-K312 WeakPolarHBondContact O-CB 3.48Å; T308-K312 PolarHBondContact O-N 3.25Å
309	I	57.8	Low	50.6	Low	119 Å²	119	101.7 Å²	101.7	61%	0.61	56%	0.561	S	S	*	*	H	α-helix	trans	-68.9	-43.1	175.5	-68	168.4	0	0	0	110.9	S305 T306 K312 A313	S305-I309 VanDerWaalsContact O-CG1 3.28Å; S305-I309 WeakPolarHBondContact O-CG1 3.41Å; S305-I309 PolarHBondContact O-N 2.89Å; T306-I309 PolarHBondContact O-N 2.89Å; I309-K312 PolarHBondContact O-N 3.49Å; I309-A313 VanDerWaalsContact O-CB 3.32Å; I309-A313 WeakPolarHBondContact O-CB 3.42Å; I309-A313 PolarHBondContact O-N 2.65Å
310	L	57.9	Low	52.1	Low	112 Å²	112	97.4 Å²	97.4	59%	0.586	54%	0.541	S	S	*	.	H	α-helix	trans	-64.7	-44.3	176.8	-126.8	154.7	0	0	0	111.3	T306 K312 A313 E314	T306-L310 WeakPolarHBondContact O-CB 3.01Å; T306-L310 PolarHBondContact O-N 3.21Å; L310-K312 VanDerWaalsContact C-N 3.34Å; L310-K312 PolarHBondContact O-N 3.41Å; L310-A313 PolarHBondContact O-N 2.9Å; L310-E314 WeakPolarHBondContact O-CB 3.18Å; L310-E314 PolarHBondContact O-N 3.43Å
311	N	55.9	Low	52.8	Low	39 Å²	39	94 Å²	94	21%	0.209	52%	0.52	C	S	.	.	H	α-helix	trans	-63.9	-35.5	173.6	-79.7	-41.9	0	0	0	113.1	K268 T307 R315	K268-N311 VanDerWaalsContact CE-OD1 3.3Å; K268-N311 WeakPolarHBondContact CE-OD1 3.36Å; K268-N311 PolarHBondContact NZ-OD1 3.26Å; T307-N311 WeakPolarHBondContact O-CB 3.26Å; T307-N311 PolarHBondContact O-N 3.1Å; T307-N311 PolarHBondContact O-ND2 3.35Å; N311-R315 VanDerWaalsContact O-CB 3.3Å; N311-R315 WeakPolarHBondContact O-CB 3.27Å; N311-R315 WeakPolarHBondContact O-CG 3.32Å; N311-R315 PolarHBondContact O-N 3.4Å
312	K	55.8	Low	54	Low	153 Å²	153	91.5 Å²	91.5	67%	0.665	50%	0.499	S	S	*	.	H	α-helix	trans	-72.7	-39	176.4	-170.4	173.4	-177.3	175.9	0	111.5	T308 I309 L310 A316	T308-K312 WeakPolarHBondContact O-CB 3.48Å; T308-K312 PolarHBondContact O-N 3.25Å; I309-K312 PolarHBondContact O-N 3.49Å; L310-K312 VanDerWaalsContact C-N 3.34Å; L310-K312 PolarHBondContact O-N 3.41Å; K312-A316 WeakPolarHBondContact O-CB 3.41Å; K312-A316 PolarHBondContact O-N 3.04Å
313	A	58.2	Low	55.3	Low	58 Å²	58	87.6 Å²	87.6	48%	0.479	49%	0.487	S	S	.	.	H	α-helix	trans	-67.3	-39.9	174.6	0	0	0	0	0	111.8	I309 L310 A316 R317	I309-A313 VanDerWaalsContact O-CB 3.32Å; I309-A313 WeakPolarHBondContact O-CB 3.42Å; I309-A313 PolarHBondContact O-N 2.65Å; L310-A313 PolarHBondContact O-N 2.9Å; A313-A316 PolarHBondContact O-N 2.84Å; A313-R317 VanDerWaalsContact O-CB 3.3Å; A313-R317 WeakPolarHBondContact O-CB 3.46Å; A313-R317 PolarHBondContact O-N 3.26Å
314	E	57.1	Low	56.5	Low	78 Å²	78	89.1 Å²	89.1	36%	0.364	48%	0.481	S	S	.	.	H	α-helix	trans	-70.9	-45.2	177.7	-166.5	172.4	-145.1	0	0	111.9	K268 L310 A316 R317 S318	K268-E314 IonicContact NZ-OE2 3.57Å; K268-E314 PolarHBondContact NZ-OE2 3.49Å; L310-E314 WeakPolarHBondContact O-CB 3.18Å; L310-E314 PolarHBondContact O-N 3.43Å; E314-A316 VanDerWaalsContact C-N 3.34Å; E314-A316 PolarHBondContact O-N 2.99Å; E314-R317 PolarHBondContact O-N 3.27Å; E314-S318 WeakPolarHBondContact O-CB 3.48Å; E314-S318 PolarHBondContact O-N 2.99Å
315	R	56.8	Low	57.5	Low	152 Å²	152	86.1 Å²	86.1	57%	0.574	46%	0.458	S	S	*	.	H	α-helix	trans	-60.9	-40.2	170.1	-78.9	-170.9	-142.6	115.5	2.2	112.3	N311 R317 N319	N311-R315 VanDerWaalsContact O-CB 3.3Å; N311-R315 WeakPolarHBondContact O-CB 3.27Å; N311-R315 WeakPolarHBondContact O-CG 3.32Å; N311-R315 PolarHBondContact O-N 3.4Å; R315-R317 VanDerWaalsContact C-N 3.34Å; R315-N319 VanDerWaalsContact O-CB 3.27Å; R315-N319 WeakPolarHBondContact O-CB 3.26Å; R315-N319 PolarHBondContact O-N 3.05Å; R315-N319 PolarHBondContact O-ND2 3.31Å
316	A	53.7	Low	58.7	Low	52 Å²	52	88.6 Å²	88.6	43%	0.43	46%	0.463	S	S	.	.	H	α-helix	trans	-65.7	-37.9	176.6	0	0	0	0	0	111.6	K312 A313 E314 T320	K312-A316 WeakPolarHBondContact O-CB 3.41Å; K312-A316 PolarHBondContact O-N 3.04Å; A313-A316 PolarHBondContact O-N 2.84Å; E314-A316 VanDerWaalsContact C-N 3.34Å; E314-A316 PolarHBondContact O-N 2.99Å; A316-T320 WeakPolarHBondContact O-CB 3.37Å; A316-T320 PolarHBondContact O-N 2.95Å; A316-T320 VanDerWaalsContact O-N 3.1Å; A316-T320 PolarHBondContact O-OG1 2.94Å
317	R	56.8	Low	59.5	Low	208 Å²	208	86.9 Å²	86.9	79%	0.785	46%	0.458	S	S	*	.	H	α-helix	trans	-69	-43.2	177.1	-168.7	177.3	-179.6	122.1	-3.7	112.3	A313 E314 R315 T320 S321	A313-R317 VanDerWaalsContact O-CB 3.3Å; A313-R317 WeakPolarHBondContact O-CB 3.46Å; A313-R317 PolarHBondContact O-N 3.26Å; E314-R317 PolarHBondContact O-N 3.27Å; R315-R317 VanDerWaalsContact C-N 3.34Å; R317-T320 PolarHBondContact O-N 3.39Å; R317-S321 PolarHBondContact O-N 2.98Å
318	S	57.5	Low	60.2	Low	33 Å²	33	88.7 Å²	88.7	23%	0.231	46%	0.459	C	S	.	.	H	α-helix	trans	-63.6	-49.9	174.1	153.5	0	0	0	0	112.1	E314 T320 S321 E322	E314-S318 WeakPolarHBondContact O-CB 3.48Å; E314-S318 PolarHBondContact O-N 2.99Å; S318-T320 PolarHBondContact O-N 3.41Å; S318-T320 VanDerWaalsContact O-N 3.14Å; S318-S321 PolarHBondContact O-N 3.37Å; S318-S321 PolarHBondContact O-OG 3.44Å; S318-E322 PolarHBondContact O-N 2.92Å
319	N	59	Low	61.2	Low	101 Å²	101	91 Å²	91	54%	0.54	46%	0.459	S	S	.	.	H	α-helix	trans	-59.7	-31.8	175.9	-73.1	-13.8	0	0	0	112.1	R315 A323	R315-N319 VanDerWaalsContact O-CB 3.27Å; R315-N319 WeakPolarHBondContact O-CB 3.26Å; R315-N319 PolarHBondContact O-N 3.05Å; R315-N319 PolarHBondContact O-ND2 3.31Å; N319-A323 VanDerWaalsContact O-CB 3.25Å; N319-A323 WeakPolarHBondContact O-CB 3.4Å; N319-A323 PolarHBondContact O-N 3.23Å; N319-A323 VanDerWaalsContact O-N 3.09Å
320	T	60.5	Low	62	Low	71 Å²	71	91.5 Å²	91.5	44%	0.436	45%	0.453	S	S	.	.	H	α-helix	trans	-75	-33	176.3	-53.7	0	0	0	0	112.4	A316 R317 S318 K324	A316-T320 WeakPolarHBondContact O-CB 3.37Å; A316-T320 PolarHBondContact O-N 2.95Å; A316-T320 VanDerWaalsContact O-N 3.1Å; A316-T320 PolarHBondContact O-OG1 2.94Å; R317-T320 PolarHBondContact O-N 3.39Å; S318-T320 PolarHBondContact O-N 3.41Å; S318-T320 VanDerWaalsContact O-N 3.14Å; T320-K324 HydrophobicContact CG2-CD 4.36Å; T320-K324 WeakPolarHBondContact O-CB 3.49Å; T320-K324 WeakPolarHBondContact O-CD 3.21Å; T320-K324 WeakPolarHBondContact O-CG 3.25Å; T320-K324 PolarHBondContact O-N 2.85Å; T320-K324 VanDerWaalsContact O-N 3.15Å
321	S	64.1	Low	62.6	Low	31 Å²	31	88.7 Å²	88.7	22%	0.217	44%	0.44	C	S	.	.	H	α-helix	trans	-72.3	-44.4	175.1	72.9	0	0	0	0	111.2	E257 R317 S318 A323 K324 L325	E257-S321 VanDerWaalsContact OE2-CB 3.29Å; E257-S321 WeakPolarHBondContact OE2-CB 3.32Å; E257-S321 PolarHBondContact OE2-OG 3.26Å; R317-S321 PolarHBondContact O-N 2.98Å; S318-S321 PolarHBondContact O-N 3.37Å; S318-S321 PolarHBondContact O-OG 3.44Å; S321-A323 PolarHBondContact O-N 2.91Å; S321-K324 WeakPolarHBondContact O-CB 3.2Å; S321-K324 PolarHBondContact O-N 2.99Å; S321-L325 WeakPolarHBondContact O-CB 3.25Å; S321-L325 PolarHBondContact O-N 3.42Å
322	E	65	Low	63.3	Low	78 Å²	78	87.3 Å²	87.3	36%	0.364	43%	0.433	S	S	.	.	H	α-helix	trans	-61.2	-45.3	175.9	-70.7	-170.9	177.1	0	0	112.1	S318 K324 L325 Q326	S318-E322 PolarHBondContact O-N 2.92Å; E322-K324 VanDerWaalsContact C-N 3.35Å; E322-K324 PolarHBondContact O-N 3.17Å; E322-L325 WeakPolarHBondContact O-CB 3.36Å; E322-L325 PolarHBondContact O-N 3.22Å; E322-Q326 WeakPolarHBondContact O-CB 3.35Å; E322-Q326 VanDerWaalsContact O-CG 3.31Å; E322-Q326 WeakPolarHBondContact O-CG 3.28Å; E322-Q326 PolarHBondContact O-N 3.29Å
323	A	64.8	Low	64.4	Low	57 Å²	57	87 Å²	87	47%	0.471	43%	0.427	S	S	.	.	H	α-helix	trans	-63.6	-38.5	176	0	0	0	0	0	112.5	N319 S321 L325 A327	N319-A323 VanDerWaalsContact O-CB 3.25Å; N319-A323 WeakPolarHBondContact O-CB 3.4Å; N319-A323 PolarHBondContact O-N 3.23Å; N319-A323 VanDerWaalsContact O-N 3.09Å; S321-A323 PolarHBondContact O-N 2.91Å; A323-L325 VanDerWaalsContact C-N 3.34Å; A323-A327 WeakPolarHBondContact O-CB 3.2Å; A323-A327 PolarHBondContact O-N 2.97Å; A323-A327 VanDerWaalsContact O-N 3.09Å
324	K	64.9	Low	65.4	Low	135 Å²	135	84.9 Å²	84.9	59%	0.587	41%	0.408	S	S	*	.	H	α-helix	trans	-65	-38.1	173.7	-79.1	172.6	-179.5	175.3	0	111.6	T320 S321 E322 A327 K328	T320-K324 HydrophobicContact CG2-CD 4.36Å; T320-K324 WeakPolarHBondContact O-CB 3.49Å; T320-K324 WeakPolarHBondContact O-CD 3.21Å; T320-K324 WeakPolarHBondContact O-CG 3.25Å; T320-K324 PolarHBondContact O-N 2.85Å; T320-K324 VanDerWaalsContact O-N 3.15Å; S321-K324 WeakPolarHBondContact O-CB 3.2Å; S321-K324 PolarHBondContact O-N 2.99Å; E322-K324 VanDerWaalsContact C-N 3.35Å; E322-K324 PolarHBondContact O-N 3.17Å; K324-A327 PolarHBondContact O-N 3.48Å; K324-K328 WeakPolarHBondContact O-CG 3.23Å; K324-K328 PolarHBondContact O-N 3.13Å; K324-K328 VanDerWaalsContact O-N 3.11Å
325	L	65.7	Low	66.4	Low	25 Å²	25	81.2 Å²	81.2	13%	0.131	39%	0.391	C	S	.	.	H	α-helix	trans	-71.3	-42.1	179.6	-178	69	0	0	0	112.4	L250 I254 S321 E322 A323 A327 K328 R329	L250-L325 HydrophobicContact CD1-CD1 4.12Å; I254-L325 HydrophobicContact CB-CD2 4.16Å; I254-L325 HydrophobicContact CD1-CD1 3.82Å; I254-L325 HydrophobicContact CD1-CD2 3.91Å; I254-L325 HydrophobicContact CD1-CG 3.89Å; I254-L325 HydrophobicContact CG1-CD1 3.42Å; I254-L325 VanDerWaalsContact CG1-CD1 3.42Å; I254-L325 HydrophobicContact CG1-CD2 3.49Å; I254-L325 VanDerWaalsContact CG1-CD2 3.49Å; I254-L325 HydrophobicContact CG1-CG 3.76Å; I254-L325 HydrophobicContact CG2-CD2 4.03Å; S321-L325 WeakPolarHBondContact O-CB 3.25Å; S321-L325 PolarHBondContact O-N 3.42Å; E322-L325 WeakPolarHBondContact O-CB 3.36Å; E322-L325 PolarHBondContact O-N 3.22Å; A323-L325 VanDerWaalsContact C-N 3.34Å; L325-A327 VanDerWaalsContact C-N 3.29Å; L325-A327 PolarHBondContact O-N 3.26Å; L325-K328 WeakPolarHBondContact O-CB 3.23Å; L325-K328 PolarHBondContact O-N 3.43Å; L325-K328 VanDerWaalsContact O-N 3.15Å; L325-R329 PolarHBondContact O-N 3.17Å
326	Q	67.8	Low	67.5	Low	110 Å²	110	78.5 Å²	78.5	51%	0.514	39%	0.386	S	S	.	.	H	α-helix	trans	-60.4	-39.2	172.2	-72.1	179.4	8.2	0	0	111.8	E322 R329 R330	E322-Q326 WeakPolarHBondContact O-CB 3.35Å; E322-Q326 VanDerWaalsContact O-CG 3.31Å; E322-Q326 WeakPolarHBondContact O-CG 3.28Å; E322-Q326 PolarHBondContact O-N 3.29Å; Q326-R329 PolarHBondContact O-N 2.89Å; Q326-R330 PolarHBondContact O-N 2.92Å; Q326-R330 VanDerWaalsContact O-N 3.1Å
327	A	65.8	Low	69.1	Low	54 Å²	54	79.1 Å²	79.1	45%	0.446	38%	0.384	S	S	.	.	H	α-helix	trans	-62.7	-41.3	173.9	0	0	0	0	0	112	A323 K324 L325 R330 V331	A323-A327 WeakPolarHBondContact O-CB 3.2Å; A323-A327 PolarHBondContact O-N 2.97Å; A323-A327 VanDerWaalsContact O-N 3.09Å; K324-A327 PolarHBondContact O-N 3.48Å; L325-A327 VanDerWaalsContact C-N 3.29Å; L325-A327 PolarHBondContact O-N 3.26Å; A327-R330 PolarHBondContact O-N 2.95Å; A327-V331 WeakPolarHBondContact O-CG2 3.35Å; A327-V331 PolarHBondContact O-N 3.17Å
328	K	67.8	Low	70.5	Confident	119 Å²	119	69.5 Å²	69.5	52%	0.517	35%	0.348	S	S	.	.	H	α-helix	trans	-63.6	-43.6	174.5	-71.4	179.4	177.9	-175.6	0	112.3	L250 K324 L325 R330 V331 I332	L250-K328 HydrophobicContact CD1-CB 3.84Å; L250-K328 HydrophobicContact CD1-CD 4.3Å; K324-K328 WeakPolarHBondContact O-CG 3.23Å; K324-K328 PolarHBondContact O-N 3.13Å; K324-K328 VanDerWaalsContact O-N 3.11Å; L325-K328 WeakPolarHBondContact O-CB 3.23Å; L325-K328 PolarHBondContact O-N 3.43Å; L325-K328 VanDerWaalsContact O-N 3.15Å; K328-R330 VanDerWaalsContact C-N 3.34Å; K328-R330 PolarHBondContact O-N 3.36Å; K328-V331 PolarHBondContact O-N 2.97Å; K328-I332 WeakPolarHBondContact O-CG1 3.37Å; K328-I332 PolarHBondContact O-N 2.98Å
329	R	71.9	Confident	71.9	Confident	126 Å²	126	68.5 Å²	68.5	48%	0.475	34%	0.341	S	S	.	.	H	α-helix	trans	-56.8	-43.7	175.1	-86.3	-176	167.4	168.8	2.2	112.7	L250 I254 L325 Q326 V331 I332 R333	L250-R329 HydrophobicContact CD2-CB 4.42Å; L250-R329 HydrophobicContact CD2-CG 3.57Å; I254-R329 HydrophobicContact CD1-CG 4.04Å; L325-R329 PolarHBondContact O-N 3.17Å; Q326-R329 PolarHBondContact O-N 2.89Å; R329-V331 VanDerWaalsContact C-N 3.33Å; R329-V331 PolarHBondContact O-N 3.35Å; R329-I332 PolarHBondContact O-N 3.37Å; R329-R333 PolarHBondContact O-N 3.36Å
330	R	74.8	Confident	73.3	Confident	129 Å²	129	66 Å²	66	49%	0.487	33%	0.334	S	S	.	.	H	α-helix	trans	-61.8	-41.5	178.4	-72.9	-176.5	-171.5	-144.9	4	112.1	Q326 A327 K328 M334	Q326-R330 PolarHBondContact O-N 2.92Å; Q326-R330 VanDerWaalsContact O-N 3.1Å; A327-R330 PolarHBondContact O-N 2.95Å; K328-R330 VanDerWaalsContact C-N 3.34Å; K328-R330 PolarHBondContact O-N 3.36Å; R330-M334 WeakPolarHBondContact O-CB 3.43Å; R330-M334 PolarHBondContact O-N 2.83Å
331	V	71.3	Confident	74.8	Confident	53 Å²	53	64.9 Å²	64.9	32%	0.321	33%	0.325	S	S	.	.	H	α-helix	trans	-64.4	-41.2	177	175.8	0	0	0	0	110.7	A327 K328 R329 M334 L335	A327-V331 WeakPolarHBondContact O-CG2 3.35Å; A327-V331 PolarHBondContact O-N 3.17Å; K328-V331 PolarHBondContact O-N 2.97Å; R329-V331 VanDerWaalsContact C-N 3.33Å; R329-V331 PolarHBondContact O-N 3.35Å; V331-M334 VanDerWaalsContact O-CB 3.32Å; V331-M334 WeakPolarHBondContact O-CB 3.18Å; V331-M334 PolarHBondContact O-N 2.96Å; V331-L335 HydrophobicContact CG1-CD1 3.95Å; V331-L335 VanDerWaalsContact O-CG 3.22Å; V331-L335 WeakPolarHBondContact O-CG 3.18Å; V331-L335 PolarHBondContact O-N 3.37Å
332	I	70.6	Confident	76	Confident	11 Å²	11	63.6 Å²	63.6	6%	0.056	32%	0.316	C	S	.	.	H	α-helix	trans	-68.9	-42.6	179.5	-67.8	164.4	0	0	0	111.6	I246 L250 K328 R329 M334 L335 M336	I246-I332 HydrophobicContact CG2-CD1 3.51Å; I246-I332 HydrophobicContact CG2-CG1 3.63Å; I246-I332 HydrophobicContact CG2-CG2 4.43Å; L250-I332 HydrophobicContact CB-CD1 3.83Å; L250-I332 HydrophobicContact CD1-CD1 3.79Å; L250-I332 HydrophobicContact CD2-CD1 3.4Å; L250-I332 VanDerWaalsContact CD2-CD1 3.4Å; L250-I332 HydrophobicContact CG-CD1 3.84Å; K328-I332 WeakPolarHBondContact O-CG1 3.37Å; K328-I332 PolarHBondContact O-N 2.98Å; R329-I332 PolarHBondContact O-N 3.37Å; I332-M334 VanDerWaalsContact C-N 3.25Å; I332-M334 PolarHBondContact O-N 3.3Å; I332-L335 WeakPolarHBondContact O-CB 3.36Å; I332-L335 PolarHBondContact O-N 3.46Å; I332-M336 PolarHBondContact O-N 2.84Å
333	R	78.9	Confident	77.3	Confident	145 Å²	145	62.4 Å²	62.4	55%	0.547	31%	0.309	S	S	.	.	H	α-helix	trans	-57.9	-41	172.9	-174.4	177.4	63.7	-167.9	3	111.5	R329 L335 M336 V337	R329-R333 PolarHBondContact O-N 3.36Å; R333-L335 VanDerWaalsContact C-N 3.32Å; R333-L335 PolarHBondContact O-N 2.89Å; R333-M336 PolarHBondContact O-N 3.43Å; R333-V337 WeakPolarHBondContact O-CG2 3.34Å; R333-V337 PolarHBondContact O-N 2.9Å; R333-V337 VanDerWaalsContact O-N 3.14Å
334	M	78.7	Confident	78.7	Confident	14 Å²	14	64.4 Å²	64.4	7%	0.069	31%	0.311	C	S	.	.	H	α-helix	trans	-60	-42.2	174	-173.2	-167.9	87.7	0	0	111.6	R330 V331 I332 V337 I338 I389 Y390 M393	R330-M334 WeakPolarHBondContact O-CB 3.43Å; R330-M334 PolarHBondContact O-N 2.83Å; V331-M334 VanDerWaalsContact O-CB 3.32Å; V331-M334 WeakPolarHBondContact O-CB 3.18Å; V331-M334 PolarHBondContact O-N 2.96Å; I332-M334 VanDerWaalsContact C-N 3.25Å; I332-M334 PolarHBondContact O-N 3.3Å; M334-V337 PolarHBondContact O-N 3.35Å; M334-I338 HydrophobicContact CE-CD1 4.25Å; M334-I338 WeakPolarHBondContact O-CG1 3.25Å; M334-I338 PolarHBondContact O-N 2.88Å; M334-I338 VanDerWaalsContact O-N 3.16Å; M334-I389 HydrophobicContact CG-CG2 3.27Å; M334-I389 HydrophobicContact SD-CG2 4.01Å; M334-Y390 HydrophobicContact CE-CD1 4.02Å; M334-Y390 HydrophobicContact CE-CE1 4.05Å; M334-Y390 HydrophobicContact SD-CD1 4.38Å; M334-M393 HydrophobicContact CB-CB 3.96Å; M334-M393 HydrophobicContact CB-CG 4.3Å; M334-M393 HydrophobicContact CG-CB 3.56Å; M334-M393 HydrophobicContact CG-CG 3.99Å; M334-M393 HydrophobicContact SD-CB 3.56Å; M334-M393 VanDerWaalsContact SD-CB 3.56Å
335	L	77.4	Confident	80	Confident	2 Å²	2	58.1 Å²	58.1	1%	0.01	28%	0.284	C	S	.	.	H	α-helix	trans	-69.2	-39	-179.9	-65.5	163.2	0	0	0	112.4	I149 R153 Y243 V331 I332 R333 V337 I338 V339	I149-L335 HydrophobicContact CG2-CD2 4.42Å; R153-L335 HydrophobicContact CB-CD1 4.26Å; R153-L335 HydrophobicContact CG-CD1 3.92Å; R153-L335 HydrophobicContact CG-CD2 4.31Å; Y243-L335 HydrophobicContact CD1-CB 3.85Å; Y243-L335 HydrophobicContact CD1-CD1 4.31Å; Y243-L335 HydrophobicContact CE1-CB 3.52Å; Y243-L335 HydrophobicContact CE1-CD1 3.8Å; Y243-L335 HydrophobicContact CE1-CD2 3.9Å; Y243-L335 HydrophobicContact CE1-CG 3.91Å; V331-L335 HydrophobicContact CG1-CD1 3.95Å; V331-L335 VanDerWaalsContact O-CG 3.22Å; V331-L335 WeakPolarHBondContact O-CG 3.18Å; V331-L335 PolarHBondContact O-N 3.37Å; I332-L335 WeakPolarHBondContact O-CB 3.36Å; I332-L335 PolarHBondContact O-N 3.46Å; R333-L335 VanDerWaalsContact C-N 3.32Å; R333-L335 PolarHBondContact O-N 2.89Å; L335-V337 VanDerWaalsContact C-N 3.31Å; L335-V337 PolarHBondContact O-N 2.93Å; L335-I338 HydrophobicContact CD2-CD1 4.33Å; L335-I338 WeakPolarHBondContact O-CB 3.35Å; L335-I338 PolarHBondContact O-N 3.47Å; L335-V339 WeakPolarHBondContact O-CG2 3.44Å; L335-V339 PolarHBondContact O-N 3.36Å; L335-V339 VanDerWaalsContact O-N 3.17Å
336	M	81.1	Confident	81.3	Confident	94 Å²	94	57.4 Å²	57.4	46%	0.463	28%	0.28	S	S	.	.	H	α-helix	trans	-62	-38.6	173.6	-68.5	-63.1	-70	0	0	112.2	I332 R333 I338 V339 A340	I332-M336 PolarHBondContact O-N 2.84Å; R333-M336 PolarHBondContact O-N 3.43Å; M336-I338 VanDerWaalsContact C-N 3.33Å; M336-I338 PolarHBondContact O-N 2.91Å; M336-V339 PolarHBondContact O-N 3.11Å; M336-A340 PolarHBondContact O-N 2.76Å
337	V	87.5	Confident	82.5	Confident	65 Å²	65	56.9 Å²	56.9	39%	0.394	28%	0.278	S	S	.	.	H	α-helix	trans	-62.2	-41.2	174.5	169	0	0	0	0	111.1	R333 M334 L335 V339 A340 L341 I389	R333-V337 WeakPolarHBondContact O-CG2 3.34Å; R333-V337 PolarHBondContact O-N 2.9Å; R333-V337 VanDerWaalsContact O-N 3.14Å; M334-V337 PolarHBondContact O-N 3.35Å; L335-V337 VanDerWaalsContact C-N 3.31Å; L335-V337 PolarHBondContact O-N 2.93Å; V337-V339 VanDerWaalsContact C-N 3.33Å; V337-V339 PolarHBondContact O-N 2.86Å; V337-A340 PolarHBondContact O-N 2.95Å; V337-L341 HydrophobicContact CG1-CD1 3.67Å; V337-L341 HydrophobicContact CG1-CG 4.38Å; V337-L341 WeakPolarHBondContact O-CB 3.26Å; V337-L341 WeakPolarHBondContact O-CD1 3.11Å; V337-L341 VanDerWaalsContact O-CG 3.3Å; V337-L341 WeakPolarHBondContact O-CG 3.33Å; V337-L341 PolarHBondContact O-N 3.09Å; V337-I389 HydrophobicContact CG1-CD1 4.3Å
338	I	85.1	Confident	83.8	Confident	6 Å²	6	55.9 Å²	55.9	3%	0.031	27%	0.267	C	S	.	.	H	α-helix	trans	-60	-43.4	176.7	-68.7	167.3	0	0	0	111.1	L146 M334 L335 M336 L341 F342 I389 Y390	L146-I338 HydrophobicContact CD2-CG2 3.66Å; M334-I338 HydrophobicContact CE-CD1 4.25Å; M334-I338 WeakPolarHBondContact O-CG1 3.25Å; M334-I338 PolarHBondContact O-N 2.88Å; M334-I338 VanDerWaalsContact O-N 3.16Å; L335-I338 HydrophobicContact CD2-CD1 4.33Å; L335-I338 WeakPolarHBondContact O-CB 3.35Å; L335-I338 PolarHBondContact O-N 3.47Å; M336-I338 VanDerWaalsContact C-N 3.33Å; M336-I338 PolarHBondContact O-N 2.91Å; I338-L341 PolarHBondContact O-N 3.33Å; I338-F342 PolarHBondContact O-N 3.48Å; I338-I389 HydrophobicContact CD1-CG2 4.07Å; I338-I389 HydrophobicContact CG1-CD1 3.69Å; I338-I389 HydrophobicContact CG1-CG2 3.97Å; I338-Y390 HydrophobicContact CD1-CE1 3.97Å
339	V	86.7	Confident	84.9	Confident	13 Å²	13	50.8 Å²	50.8	8%	0.079	25%	0.246	C	C	.	.	H	α-helix	trans	-63	-49	177.4	-179.8	0	0	0	0	111.4	M239 I240 Y243 L335 M336 V337 L341 F342 F343	M239-V339 HydrophobicContact CB-CG2 4.23Å; I240-V339 HydrophobicContact CG1-CG1 4.3Å; Y243-V339 HydrophobicContact CD2-CG2 3.18Å; Y243-V339 HydrophobicContact CE2-CG2 3.29Å; Y243-V339 HydrophobicContact CG-CG2 4.27Å; L335-V339 WeakPolarHBondContact O-CG2 3.44Å; L335-V339 PolarHBondContact O-N 3.36Å; L335-V339 VanDerWaalsContact O-N 3.17Å; M336-V339 PolarHBondContact O-N 3.11Å; V337-V339 VanDerWaalsContact C-N 3.33Å; V337-V339 PolarHBondContact O-N 2.86Å; V339-L341 VanDerWaalsContact C-N 3.27Å; V339-L341 PolarHBondContact O-N 2.71Å; V339-F342 WeakPolarHBondContact O-CB 3.39Å; V339-F342 PolarHBondContact O-N 2.03Å; V339-F342 VanDerWaalsContact O-N 3.14Å; V339-F343 HydrophobicContact CG1-CD2 3.95Å; V339-F343 HydrophobicContact CG1-CE2 3.61Å; V339-F343 WeakPolarHBondContact O-CD2 3.21Å; V339-F343 PolarHBondContact O-N 2.86Å
340	A	89.8	Confident	85.8	Confident	48 Å²	48	45.5 Å²	45.5	40%	0.397	23%	0.226	S	C	.	.	H	α-helix	trans	-58.4	-43.1	-179.9	0	0	0	0	0	111.2	M336 V337 F342 F343 I344	M336-A340 PolarHBondContact O-N 2.76Å; V337-A340 PolarHBondContact O-N 2.95Å; A340-F342 PolarHBondContact O-N 3.5Å; A340-F343 PolarHBondContact O-N 3.43Å; A340-I344 WeakPolarHBondContact O-CD1 3.22Å; A340-I344 VanDerWaalsContact O-CG1 3.26Å; A340-I344 WeakPolarHBondContact O-CG1 3.3Å; A340-I344 PolarHBondContact O-N 2.89Å
341	L	90.5	Very high	86.6	Confident	47 Å²	47	42.3 Å²	42.3	25%	0.246	22%	0.223	C	C	.	.	H	α-helix	trans	-67.3	-34.1	177.8	-72.4	166.5	0	0	0	113	V337 I338 V339 F343 I344 C345 V385 I389	V337-L341 HydrophobicContact CG1-CD1 3.67Å; V337-L341 HydrophobicContact CG1-CG 4.38Å; V337-L341 WeakPolarHBondContact O-CB 3.26Å; V337-L341 WeakPolarHBondContact O-CD1 3.11Å; V337-L341 VanDerWaalsContact O-CG 3.3Å; V337-L341 WeakPolarHBondContact O-CG 3.33Å; V337-L341 PolarHBondContact O-N 3.09Å; I338-L341 PolarHBondContact O-N 3.33Å; V339-L341 VanDerWaalsContact C-N 3.27Å; V339-L341 PolarHBondContact O-N 2.71Å; L341-F343 VanDerWaalsContact C-N 3.34Å; L341-F343 PolarHBondContact O-N 3.34Å; L341-I344 PolarHBondContact O-N 3.33Å; L341-C345 WeakPolarHBondContact O-CB 3.03Å; L341-C345 PolarHBondContact O-N 3.04Å; L341-C345 PolarHBondContact O-SG 2.99Å; L341-C345 VanDerWaalsContact O-SG 3.41Å; L341-V385 HydrophobicContact CD1-CG1 3.54Å; L341-I389 HydrophobicContact CD1-CD1 3.53Å; L341-I389 HydrophobicContact CD1-CG1 4.4Å
342	F	90.4	Very high	87.5	Confident	5 Å²	5	40.6 Å²	40.6	2%	0.022	21%	0.213	C	C	.	.	H	α-helix	trans	-57.3	-49	172.4	176.4	-95.4	0	0	0	110.9	T143 L146 L231 F232 P235 M239 I338 V339 A340 W346	T143-F342 HydrophobicContact CG2-CE2 3.95Å; T143-F342 HydrophobicContact CG2-CZ 4.05Å; L146-F342 HydrophobicContact CD1-CD2 4.05Å; L231-F342 WeakPolarHBondContact O-CZ 3.22Å; F232-F342 AromaticContact CD2-CE1 3.77Å; F232-F342 HydrophobicContact CD2-CE1 3.77Å; F232-F342 HydrophobicContact CD2-CZ 4.14Å; F232-F342 HydrophobicContact CE2-CE1 4.17Å; P235-F342 HydrophobicContact CB-CZ 4.38Å; M239-F342 HydrophobicContact CE-CB 4.36Å; M239-F342 HydrophobicContact CE-CD1 3.56Å; M239-F342 HydrophobicContact CE-CD2 4.22Å; M239-F342 HydrophobicContact CE-CE1 3.8Å; M239-F342 HydrophobicContact CE-CE2 4.42Å; M239-F342 HydrophobicContact CE-CG 3.78Å; M239-F342 HydrophobicContact CE-CZ 4.22Å; I338-F342 PolarHBondContact O-N 3.48Å; V339-F342 WeakPolarHBondContact O-CB 3.39Å; V339-F342 PolarHBondContact O-N 2.03Å; V339-F342 VanDerWaalsContact O-N 3.14Å; A340-F342 PolarHBondContact O-N 3.5Å; F342-W346 AromaticContact CD2-CD1 3.57Å; F342-W346 HydrophobicContact CD2-CG 4.44Å; F342-W346 AromaticContact CE2-CD1 3.85Å; F342-W346 HydrophobicContact CE2-CG 4.38Å; F342-W346 VanDerWaalsContact O-CB 3.29Å; F342-W346 WeakPolarHBondContact O-CB 3.28Å; F342-W346 VanDerWaalsContact O-CD1 3.24Å; F342-W346 PolarHBondContact O-N 3.46Å
343	F	91.9	Very high	88.5	Confident	53 Å²	53	41.7 Å²	41.7	23%	0.232	22%	0.219	C	C	.	.	H	α-helix	trans	-64.8	-47.2	177.1	-71.4	-74.8	0	0	0	112.3	F232 I240 V339 A340 L341 C345 M347	F232-F343 HydrophobicContact CE1-CD1 4.24Å; F232-F343 HydrophobicContact CE1-CE1 4.28Å; F232-F343 AromaticContact CE2-CD1 3.81Å; F232-F343 HydrophobicContact CE2-CD1 3.81Å; F232-F343 HydrophobicContact CE2-CE1 4.3Å; F232-F343 AromaticContact CZ-CD1 3.47Å; F232-F343 HydrophobicContact CZ-CD1 3.47Å; F232-F343 VanDerWaalsContact CZ-CD1 3.47Å; F232-F343 AromaticContact CZ-CE1 3.92Å; F232-F343 HydrophobicContact CZ-CE1 3.92Å; I240-F343 HydrophobicContact CD1-CE2 3.86Å; I240-F343 HydrophobicContact CD1-CZ 3.66Å; I240-F343 HydrophobicContact CG1-CE2 4.17Å; I240-F343 HydrophobicContact CG1-CZ 4.36Å; V339-F343 HydrophobicContact CG1-CD2 3.95Å; V339-F343 HydrophobicContact CG1-CE2 3.61Å; V339-F343 WeakPolarHBondContact O-CD2 3.21Å; V339-F343 PolarHBondContact O-N 2.86Å; A340-F343 PolarHBondContact O-N 3.43Å; L341-F343 VanDerWaalsContact C-N 3.34Å; L341-F343 PolarHBondContact O-N 3.34Å; F343-C345 PolarHBondContact O-N 3.05Å; F343-M347 WeakPolarHBondContact O-CB 3.39Å; F343-M347 PolarHBondContact O-N 3.25Å
344	I	93.4	Very high	89	Confident	99 Å²	99	35.9 Å²	35.9	51%	0.508	20%	0.199	S	C	.	.	H	α-helix	trans	-62.1	-43.1	-177.8	-68.3	164.5	0	0	0	111.7	A340 L341 P348	A340-I344 WeakPolarHBondContact O-CD1 3.22Å; A340-I344 VanDerWaalsContact O-CG1 3.26Å; A340-I344 WeakPolarHBondContact O-CG1 3.3Å; A340-I344 PolarHBondContact O-N 2.89Å; L341-I344 PolarHBondContact O-N 3.33Å; I344-P348 WeakPolarHBondContact O-CD 3.34Å
345	C	92.9	Very high	89.6	Confident	3 Å²	3	40.5 Å²	40.5	2%	0.02	22%	0.216	C	C	.	.	H	α-helix	trans	-76.7	-37.6	-176.8	-71.3	0	0	0	0	113	L341 F343 L378 S379	L341-C345 WeakPolarHBondContact O-CB 3.03Å; L341-C345 PolarHBondContact O-N 3.04Å; L341-C345 PolarHBondContact O-SG 2.99Å; L341-C345 VanDerWaalsContact O-SG 3.41Å; F343-C345 PolarHBondContact O-N 3.05Å; C345-L378 PolarHBondContact SG-O 3.24Å; C345-S379 WeakPolarHBondContact O-CA 3.25Å
346	W	92.4	Very high	90.1	Very high	10 Å²	10	42.9 Å²	42.9	4%	0.038	23%	0.226	C	C	.	.	H	α-helix	trans	-100.1	-30.1	-169.9	-67.8	102.4	0	0	0	114.5	M104 V139 F232 F342 L349 Y350 S382	M104-W346 HydrophobicContact CE-CH2 3.93Å; M104-W346 HydrophobicContact CE-CZ2 4.44Å; V139-W346 HydrophobicContact CB-CH2 4.19Å; V139-W346 HydrophobicContact CB-CZ3 4.36Å; V139-W346 HydrophobicContact CG1-CE3 4.12Å; V139-W346 HydrophobicContact CG1-CH2 3.78Å; V139-W346 HydrophobicContact CG1-CZ2 4.25Å; V139-W346 HydrophobicContact CG1-CZ3 3.65Å; V139-W346 HydrophobicContact CG2-CH2 3.5Å; V139-W346 HydrophobicContact CG2-CZ2 4.44Å; V139-W346 HydrophobicContact CG2-CZ3 3.73Å; F232-W346 HydrophobicContact CD2-CB 4.14Å; F232-W346 HydrophobicContact CE2-CB 4.22Å; F342-W346 AromaticContact CD2-CD1 3.57Å; F342-W346 HydrophobicContact CD2-CG 4.44Å; F342-W346 AromaticContact CE2-CD1 3.85Å; F342-W346 HydrophobicContact CE2-CG 4.38Å; F342-W346 VanDerWaalsContact O-CB 3.29Å; F342-W346 WeakPolarHBondContact O-CB 3.28Å; F342-W346 VanDerWaalsContact O-CD1 3.24Å; F342-W346 PolarHBondContact O-N 3.46Å; W346-L349 HydrophobicContact CE3-CD2 4.11Å; W346-L349 HydrophobicContact CZ3-CD2 3.9Å; W346-L349 PolarHBondContact O-N 3.35Å; W346-Y350 HydrophobicContact CB-CD2 3.98Å; W346-Y350 HydrophobicContact CB-CE2 3.89Å; W346-Y350 HydrophobicContact CD2-CE2 4.4Å; W346-Y350 AromaticContact CE3-CE2 3.98Å; W346-Y350 HydrophobicContact CE3-CE2 3.98Å; W346-Y350 HydrophobicContact CG-CE2 4.4Å; W346-Y350 VanDerWaalsContact O-CD2 3.27Å; W346-Y350 WeakPolarHBondContact O-CD2 3.42Å; W346-Y350 PolarHBondContact O-N 2.93Å; W346-Y350 VanDerWaalsContact O-N 3.12Å; W346-S382 VanDerWaalsContact CZ2-OG 3.22Å; W346-S382 WeakPolarHBondContact CZ2-OG 3.15Å; W346-S382 PolarHBondContact NE1-OG 2.94Å
347	M	92.8	Very high	90.5	Very high	99 Å²	99	38.8 Å²	38.8	49%	0.488	21%	0.208	S	C	.	.	H	α-helix	trans	-54.7	-47.9	-177.3	-172.9	-171.5	88.5	0	0	112.5	F232 F343 L349 Y350 S351	F232-M347 HydrophobicContact CE1-CG 4.48Å; F232-M347 HydrophobicContact CE2-CB 3.97Å; F232-M347 HydrophobicContact CZ-CB 3.62Å; F232-M347 HydrophobicContact CZ-CG 3.87Å; F343-M347 WeakPolarHBondContact O-CB 3.39Å; F343-M347 PolarHBondContact O-N 3.25Å; M347-L349 VanDerWaalsContact C-N 3.28Å; M347-L349 PolarHBondContact O-N 2.96Å; M347-Y350 PolarHBondContact O-N 3.3Å; M347-S351 WeakPolarHBondContact O-CB 3.43Å; M347-S351 PolarHBondContact O-N 2.73Å; M347-S351 PolarHBondContact O-OG 3.37Å
348	P	93.1	Very high	90.6	Very high	33 Å²	33	41.5 Å²	41.5	21%	0.214	21%	0.214	C	C	.	.	H	α-helix	trans	-62.3	-37.4	-176.4	-25.1	39	0	0	0	112.5	I344 V352 I375 L378	I344-P348 WeakPolarHBondContact O-CD 3.34Å; P348-V352 WeakPolarHBondContact O-CB 3.45Å; P348-V352 WeakPolarHBondContact O-CG2 3.24Å; P348-V352 PolarHBondContact O-N 2.94Å; P348-I375 HydrophobicContact CB-CG1 4.42Å; P348-I375 HydrophobicContact CB-CG2 4.15Å; P348-L378 HydrophobicContact CB-CD2 4.5Å; P348-L378 HydrophobicContact CG-CD2 3.84Å
349	L	90.9	Very high	90.8	Very high	11 Å²	11	44.6 Å²	44.6	6%	0.058	23%	0.231	C	C	.	.	H	α-helix	trans	-67.7	-48.3	179.1	-177.5	67.2	0	0	0	111.4	W346 M347 V352 N353 I375	W346-L349 HydrophobicContact CE3-CD2 4.11Å; W346-L349 HydrophobicContact CZ3-CD2 3.9Å; W346-L349 PolarHBondContact O-N 3.35Å; M347-L349 VanDerWaalsContact C-N 3.28Å; M347-L349 PolarHBondContact O-N 2.96Å; L349-V352 PolarHBondContact O-N 3.38Å; L349-N353 WeakPolarHBondContact O-CB 3.44Å; L349-N353 PolarHBondContact O-N 3.49Å; L349-N353 PolarHBondContact O-ND2 3.48Å; L349-I375 HydrophobicContact CB-CG2 4Å; L349-I375 HydrophobicContact CD1-CG2 4.07Å
350	Y	92.4	Very high	90.6	Very high	16 Å²	16	47.3 Å²	47.3	6%	0.063	25%	0.245	C	C	.	.	H	α-helix	trans	-67.1	-37.8	179.6	-74.7	-67.2	0	0	0	112.4	V139 L228 L231 F232 W346 M347 T354	V139-Y350 WeakPolarHBondContact CG1-OH 3.13Å; L228-Y350 HydrophobicContact CD1-CG 4.32Å; L231-Y350 HydrophobicContact CB-CE1 4.38Å; L231-Y350 VanDerWaalsContact CB-OH 3.23Å; L231-Y350 WeakPolarHBondContact CB-OH 3.35Å; F232-Y350 HydrophobicContact CB-CD2 3.84Å; F232-Y350 HydrophobicContact CB-CE2 3.98Å; F232-Y350 HydrophobicContact CB-CG 4.31Å; F232-Y350 AromaticContact CD2-CD2 3.79Å; F232-Y350 HydrophobicContact CD2-CD2 3.79Å; F232-Y350 HydrophobicContact CD2-CE2 4.17Å; F232-Y350 AromaticContact CG-CD2 4Å; F232-Y350 HydrophobicContact CG-CD2 4Å; F232-Y350 HydrophobicContact CG-CE2 4.46Å; W346-Y350 HydrophobicContact CB-CD2 3.98Å; W346-Y350 HydrophobicContact CB-CE2 3.89Å; W346-Y350 HydrophobicContact CD2-CE2 4.4Å; W346-Y350 AromaticContact CE3-CE2 3.98Å; W346-Y350 HydrophobicContact CE3-CE2 3.98Å; W346-Y350 HydrophobicContact CG-CE2 4.4Å; W346-Y350 VanDerWaalsContact O-CD2 3.27Å; W346-Y350 WeakPolarHBondContact O-CD2 3.42Å; W346-Y350 PolarHBondContact O-N 2.93Å; W346-Y350 VanDerWaalsContact O-N 3.12Å; M347-Y350 PolarHBondContact O-N 3.3Å; Y350-T354 WeakPolarHBondContact O-CB 3.38Å; Y350-T354 PolarHBondContact O-N 3.4Å; Y350-T354 PolarHBondContact O-OG1 2.83Å
351	S	91.4	Very high	90.2	Very high	62 Å²	62	53.7 Å²	53.7	43%	0.434	26%	0.264	S	S	.	.	H	α-helix	trans	-61.7	-46.1	175.1	-64.3	0	0	0	0	111.7	M347 T354 W355	M347-S351 WeakPolarHBondContact O-CB 3.43Å; M347-S351 PolarHBondContact O-N 2.73Å; M347-S351 PolarHBondContact O-OG 3.37Å; S351-T354 PolarHBondContact O-N 2.89Å; S351-W355 WeakPolarHBondContact O-CB 3.33Å; S351-W355 PolarHBondContact O-N 3.37Å
352	V	90	Very high	89.9	Confident	16 Å²	16	53.5 Å²	53.5	10%	0.097	27%	0.267	C	S	.	.	H	α-helix	trans	-68.6	-41.5	179.6	165.2	0	0	0	0	112.6	P348 L349 T354 W355 K356 L367 I375	P348-V352 WeakPolarHBondContact O-CB 3.45Å; P348-V352 WeakPolarHBondContact O-CG2 3.24Å; P348-V352 PolarHBondContact O-N 2.94Å; L349-V352 PolarHBondContact O-N 3.38Å; V352-T354 VanDerWaalsContact C-N 3.29Å; V352-T354 PolarHBondContact O-N 3.34Å; V352-W355 PolarHBondContact O-N 2.78Å; V352-K356 HydrophobicContact CG1-CD 4.31Å; V352-K356 HydrophobicContact CG1-CG 4.47Å; V352-K356 WeakPolarHBondContact O-CG 3.17Å; V352-K356 PolarHBondContact O-N 3.43Å; V352-L367 HydrophobicContact CB-CD2 4.09Å; V352-L367 HydrophobicContact CG1-CD2 3.28Å; V352-L367 HydrophobicContact CG2-CD2 3.6Å; V352-I375 HydrophobicContact CB-CD1 4.5Å; V352-I375 HydrophobicContact CG2-CD1 3.64Å
353	N	90.3	Very high	89.5	Confident	35 Å²	35	53.3 Å²	53.3	19%	0.187	27%	0.266	C	S	.	.	H	α-helix	trans	-62.7	-40.3	177.3	-71.9	-15.1	0	0	0	111.4	Y224 L349 A357	Y224-N353 HydrophobicContact CD1-CB 3.76Å; Y224-N353 HydrophobicContact CE1-CB 3.88Å; L349-N353 WeakPolarHBondContact O-CB 3.44Å; L349-N353 PolarHBondContact O-N 3.49Å; L349-N353 PolarHBondContact O-ND2 3.48Å; N353-A357 PolarHBondContact O-N 3.25Å
354	T	90.7	Very high	88.8	Confident	22 Å²	22	55.9 Å²	55.9	14%	0.135	28%	0.279	C	S	.	.	H	α-helix	trans	-66.8	-45	175	-51.4	0	0	0	0	110.5	V225 L228 Y350 S351 V352 K356 A357 F358	V225-T354 HydrophobicContact CG2-CG2 4.43Å; L228-T354 HydrophobicContact CD2-CG2 4.37Å; Y350-T354 WeakPolarHBondContact O-CB 3.38Å; Y350-T354 PolarHBondContact O-N 3.4Å; Y350-T354 PolarHBondContact O-OG1 2.83Å; S351-T354 PolarHBondContact O-N 2.89Å; V352-T354 VanDerWaalsContact C-N 3.29Å; V352-T354 PolarHBondContact O-N 3.34Å; T354-K356 PolarHBondContact O-N 3.34Å; T354-A357 WeakPolarHBondContact O-CB 3.28Å; T354-A357 PolarHBondContact O-N 3.43Å; T354-A357 VanDerWaalsContact O-N 3.12Å; T354-F358 HydrophobicContact CG2-CD2 3.93Å; T354-F358 HydrophobicContact CG2-CE2 3.72Å; T354-F358 VanDerWaalsContact O-CD2 3.28Å; T354-F358 WeakPolarHBondContact O-CD2 3.27Å; T354-F358 PolarHBondContact O-N 3.4Å
355	W	91.4	Very high	88	Confident	111 Å²	111	55.2 Å²	55.2	42%	0.42	28%	0.282	S	S	.	.	H	α-helix	trans	-59	-46.3	178.1	-173.5	4.5	0	0	0	111.9	S351 V352 A357 F358 D359 A363 A366 L367	S351-W355 WeakPolarHBondContact O-CB 3.33Å; S351-W355 PolarHBondContact O-N 3.37Å; V352-W355 PolarHBondContact O-N 2.78Å; W355-A357 PolarHBondContact O-N 3.5Å; W355-F358 PolarHBondContact O-N 2.84Å; W355-F358 VanDerWaalsContact O-N 3.1Å; W355-D359 PolarHBondContact O-N 3.5Å; W355-A363 HydrophobicContact CD2-CB 4.32Å; W355-A363 HydrophobicContact CG-CB 4.23Å; W355-A366 HydrophobicContact CH2-CB 4.2Å; W355-L367 HydrophobicContact CE3-CD1 4.33Å; W355-L367 HydrophobicContact CH2-CD1 4.46Å; W355-L367 HydrophobicContact CZ3-CD1 3.95Å
356	K	87.6	Confident	87.2	Confident	52 Å²	52	57.9 Å²	57.9	23%	0.226	31%	0.305	C	S	.	.	H	α-helix	trans	-57.4	-35.6	176	-75.9	-177.6	174.8	-170.9	0	113.1	V352 T354 F358 N360 A363	V352-K356 HydrophobicContact CG1-CD 4.31Å; V352-K356 HydrophobicContact CG1-CG 4.47Å; V352-K356 WeakPolarHBondContact O-CG 3.17Å; V352-K356 PolarHBondContact O-N 3.43Å; T354-K356 PolarHBondContact O-N 3.34Å; K356-F358 VanDerWaalsContact C-N 3.35Å; K356-N360 WeakPolarHBondContact O-CA 3.36Å; K356-N360 WeakPolarHBondContact O-CB 3.35Å; K356-N360 PolarHBondContact O-N 3.23Å; K356-A363 HydrophobicContact CB-CB 4.5Å; K356-A363 HydrophobicContact CG-CB 3.71Å
357	A	88.6	Confident	86.3	Confident	9 Å²	9	58 Å²	58	7%	0.074	31%	0.306	C	S	.	.	H	α-helix	trans	-69.8	-29	178.8	0	0	0	0	0	113.6	E220 Q221 Y224 N353 T354 W355	E220-A357 HydrophobicContact CG-CB 4.17Å; Q221-A357 HydrophobicContact CG-CB 4.25Å; Q221-A357 WeakPolarHBondContact CG-O 3.43Å; Q221-A357 PolarHBondContact NE2-O 3.32Å; Y224-A357 HydrophobicContact CD2-CB 3.62Å; Y224-A357 HydrophobicContact CE2-CB 4.41Å; Y224-A357 HydrophobicContact CG-CB 4.26Å; N353-A357 PolarHBondContact O-N 3.25Å; T354-A357 WeakPolarHBondContact O-CB 3.28Å; T354-A357 PolarHBondContact O-N 3.43Å; T354-A357 VanDerWaalsContact O-N 3.12Å; W355-A357 PolarHBondContact O-N 3.5Å
358	F	90.8	Very high	85	Confident	121 Å²	121	57.4 Å²	57.4	53%	0.531	31%	0.312	S	S	.	.	H	α-helix	trans	-94.1	-37	179.3	-76.3	-79.4	0	0	0	113.3	Q221 V225 T354 W355 K356	Q221-F358 HydrophobicContact CB-CE1 4.48Å; Q221-F358 HydrophobicContact CB-CZ 4.38Å; Q221-F358 HydrophobicContact CG-CD1 4.25Å; Q221-F358 HydrophobicContact CG-CE1 4.2Å; Q221-F358 HydrophobicContact CG-CZ 4.45Å; V225-F358 HydrophobicContact CG2-CE2 3.87Å; V225-F358 HydrophobicContact CG2-CZ 3.97Å; T354-F358 HydrophobicContact CG2-CD2 3.93Å; T354-F358 HydrophobicContact CG2-CE2 3.72Å; T354-F358 VanDerWaalsContact O-CD2 3.28Å; T354-F358 WeakPolarHBondContact O-CD2 3.27Å; T354-F358 PolarHBondContact O-N 3.4Å; W355-F358 PolarHBondContact O-N 2.84Å; W355-F358 VanDerWaalsContact O-N 3.1Å; K356-F358 VanDerWaalsContact C-N 3.35Å
359	D	88.1	Confident	83.6	Confident	72 Å²	72	58.5 Å²	58.5	39%	0.385	33%	0.329	S	S	.	.			trans	-147.4	83.1	-179.4	-174.9	-3.4	0	0	0	110.8	W355 K361 S362 A363	W355-D359 PolarHBondContact O-N 3.5Å; D359-K361 VanDerWaalsContact C-N 3.3Å; D359-K361 PolarHBondContact O-N 2.93Å; D359-K361 PolarHBondContact OD1-N 2.95Å; D359-S362 WeakPolarHBondContact OD1-CB 3.27Å; D359-S362 PolarHBondContact OD1-N 3.48Å; D359-S362 WeakPolarHBondContact OD2-CB 3.39Å; D359-A363 WeakPolarHBondContact O-CB 3.27Å; D359-A363 PolarHBondContact O-N 3.41Å; D359-A363 VanDerWaalsContact O-N 3.08Å
360	N	82.4	Confident	82.2	Confident	70 Å²	70	59.3 Å²	59.3	37%	0.374	34%	0.337	S	S	.	.	H	α-helix	trans	-64.6	-33.5	-179.8	-168.6	51.9	0	0	0	112.4	K356 E364	K356-N360 WeakPolarHBondContact O-CA 3.36Å; K356-N360 WeakPolarHBondContact O-CB 3.35Å; K356-N360 PolarHBondContact O-N 3.23Å; N360-E364 VanDerWaalsContact ND2-CD 3.26Å; N360-E364 PolarHBondContact ND2-OE1 2.91Å; N360-E364 VanDerWaalsContact O-CB 3.27Å; N360-E364 WeakPolarHBondContact O-CB 3.09Å; N360-E364 VanDerWaalsContact O-CG 3.31Å; N360-E364 WeakPolarHBondContact O-CG 3.32Å; N360-E364 PolarHBondContact O-N 3.45Å; N360-E364 PolarHBondContact OD1-OE1 2.87Å
361	K	82.1	Confident	81.2	Confident	181 Å²	181	61.1 Å²	61.1	79%	0.787	35%	0.351	S	S	*	.	H	α-helix	trans	-69.3	-48.2	-176.3	-70.4	-179.1	-178.3	173	0	111.5	D359 S365	D359-K361 VanDerWaalsContact C-N 3.3Å; D359-K361 PolarHBondContact O-N 2.93Å; D359-K361 PolarHBondContact OD1-N 2.95Å; K361-S365 WeakPolarHBondContact O-CB 3.47Å; K361-S365 PolarHBondContact O-N 3.17Å; K361-S365 PolarHBondContact O-OG 2.86Å
362	S	84.3	Confident	80.5	Confident	44 Å²	44	60 Å²	60	31%	0.308	34%	0.34	S	S	.	.	H	α-helix	trans	-64.3	-45.2	175.5	-176	0	0	0	0	110.9	D359 E364 S365 A366	D359-S362 WeakPolarHBondContact OD1-CB 3.27Å; D359-S362 PolarHBondContact OD1-N 3.48Å; D359-S362 WeakPolarHBondContact OD2-CB 3.39Å; S362-E364 PolarHBondContact O-N 2.82Å; S362-S365 PolarHBondContact O-N 2.74Å; S362-S365 PolarHBondContact O-OG 3.24Å; S362-A366 WeakPolarHBondContact O-CB 3.23Å; S362-A366 PolarHBondContact O-N 3.41Å
363	A	80.9	Confident	80	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-60.7	-47.1	178.5	0	0	0	0	0	112.2	W355 K356 D359 S365 A366 L367	W355-A363 HydrophobicContact CD2-CB 4.32Å; W355-A363 HydrophobicContact CG-CB 4.23Å; K356-A363 HydrophobicContact CB-CB 4.5Å; K356-A363 HydrophobicContact CG-CB 3.71Å; D359-A363 WeakPolarHBondContact O-CB 3.27Å; D359-A363 PolarHBondContact O-N 3.41Å; D359-A363 VanDerWaalsContact O-N 3.08Å; A363-S365 VanDerWaalsContact C-N 3.34Å; A363-S365 PolarHBondContact O-N 2.9Å; A363-A366 PolarHBondContact O-N 3.46Å; A363-L367 WeakPolarHBondContact O-CB 3.21Å; A363-L367 WeakPolarHBondContact O-CD1 3.38Å; A363-L367 PolarHBondContact O-N 3.43Å
364	E	77.2	Confident	79.6	Confident	108 Å²	108	61.4 Å²	61.4	51%	0.505	35%	0.345	S	S	.	.	H	α-helix	trans	-62.6	-39.5	177.1	-78.6	-177.7	178.9	0	0	112.2	N360 S362 S368	N360-E364 VanDerWaalsContact ND2-CD 3.26Å; N360-E364 PolarHBondContact ND2-OE1 2.91Å; N360-E364 VanDerWaalsContact O-CB 3.27Å; N360-E364 WeakPolarHBondContact O-CB 3.09Å; N360-E364 VanDerWaalsContact O-CG 3.31Å; N360-E364 WeakPolarHBondContact O-CG 3.32Å; N360-E364 PolarHBondContact O-N 3.45Å; N360-E364 PolarHBondContact OD1-OE1 2.87Å; S362-E364 PolarHBondContact O-N 2.82Å; E364-S368 WeakPolarHBondContact O-CA 3.43Å; E364-S368 VanDerWaalsContact O-CB 3.23Å; E364-S368 WeakPolarHBondContact O-CB 3.18Å; E364-S368 PolarHBondContact O-N 3.44Å
365	S	77.1	Confident	79.5	Confident	84 Å²	84	61.8 Å²	61.8	59%	0.587	35%	0.346	S	S	*	.	H	α-helix	trans	-63.8	-43.8	177.4	74.2	0	0	0	0	112.1	K361 S362 A363 S368	K361-S365 WeakPolarHBondContact O-CB 3.47Å; K361-S365 PolarHBondContact O-N 3.17Å; K361-S365 PolarHBondContact O-OG 2.86Å; S362-S365 PolarHBondContact O-N 2.74Å; S362-S365 PolarHBondContact O-OG 3.24Å; A363-S365 VanDerWaalsContact C-N 3.34Å; A363-S365 PolarHBondContact O-N 2.9Å; S365-S368 PolarHBondContact O-OG 3.39Å
366	A	77	Confident	79.2	Confident	60 Å²	60	58.4 Å²	58.4	50%	0.496	34%	0.335	S	S	.	.	H	α-helix	trans	-78.5	-29.5	-178	0	0	0	0	0	113.5	W355 S362 A363	W355-A366 HydrophobicContact CH2-CB 4.2Å; S362-A366 WeakPolarHBondContact O-CB 3.23Å; S362-A366 PolarHBondContact O-N 3.41Å; A363-A366 PolarHBondContact O-N 3.46Å
367	L	73.7	Confident	79.2	Confident	12 Å²	12	56.6 Å²	56.6	6%	0.063	33%	0.328	C	S	.	.	H	α-helix	trans	-108.5	6.7	-174.5	-80.8	77.5	0	0	0	114.2	V352 W355 A363 G369 I372 I375	V352-L367 HydrophobicContact CB-CD2 4.09Å; V352-L367 HydrophobicContact CG1-CD2 3.28Å; V352-L367 HydrophobicContact CG2-CD2 3.6Å; W355-L367 HydrophobicContact CE3-CD1 4.33Å; W355-L367 HydrophobicContact CH2-CD1 4.46Å; W355-L367 HydrophobicContact CZ3-CD1 3.95Å; A363-L367 WeakPolarHBondContact O-CB 3.21Å; A363-L367 WeakPolarHBondContact O-CD1 3.38Å; A363-L367 PolarHBondContact O-N 3.43Å; L367-G369 PolarHBondContact O-N 2.89Å; L367-I372 HydrophobicContact CB-CD1 3.95Å; L367-I372 HydrophobicContact CB-CG1 3.76Å; L367-I372 HydrophobicContact CD2-CG1 3.94Å; L367-I372 HydrophobicContact CG-CG1 4.39Å; L367-I372 WeakPolarHBondContact O-CD1 3.11Å; L367-I372 WeakPolarHBondContact O-CG1 3.46Å; L367-I375 HydrophobicContact CD2-CD1 4.31Å
368	S	64	Low	79.3	Confident	87 Å²	87	59.1 Å²	59.1	61%	0.608	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.7	123.2	178.7	53.1	0	0	0	0	112	E364 S365	E364-S368 WeakPolarHBondContact O-CA 3.43Å; E364-S368 VanDerWaalsContact O-CB 3.23Å; E364-S368 WeakPolarHBondContact O-CB 3.18Å; E364-S368 PolarHBondContact O-N 3.44Å; S365-S368 PolarHBondContact O-OG 3.39Å
369	G	64.8	Low	79.4	Confident	55 Å²	55	53.4 Å²	53.4	57%	0.567	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	85.8	-120.2	174.2	0	0	0	0	0	115.7	L367	L367-G369 PolarHBondContact O-N 2.89Å
370	A	60.5	Low	79.6	Confident	29 Å²	29	50 Å²	50	24%	0.24	30%	0.296	C	S	.	.	H	α-helix	trans	-56.8	-40.9	-168.3	0	0	0	0	0	117.2	M54 I372 S373 F374	M54-A370 HydrophobicContact CE-CB 4.44Å; A370-I372 PolarHBondContact O-N 2.92Å; A370-S373 PolarHBondContact O-N 3.35Å; A370-F374 HydrophobicContact CB-CD2 4.46Å; A370-F374 HydrophobicContact CB-CE2 4.18Å; A370-F374 WeakPolarHBondContact O-CD2 3.26Å; A370-F374 PolarHBondContact O-N 3.48Å
371	P	73.2	Confident	80	Confident	53 Å²	53	48.3 Å²	48.3	34%	0.344	29%	0.289	S	S	.	.	H	α-helix	trans	-62.8	-37.6	-169.9	-25.1	36	0	0	0	113.6	S373 F374 I375	P371-S373 PolarHBondContact O-N 3.31Å; P371-F374 PolarHBondContact O-N 3.01Å; P371-I375 VanDerWaalsContact O-CG1 3.31Å; P371-I375 WeakPolarHBondContact O-CG1 3.46Å; P371-I375 PolarHBondContact O-N 3.4Å; P371-I375 VanDerWaalsContact O-N 3.08Å
372	I	76.6	Confident	80.4	Confident	40 Å²	40	40.4 Å²	40.4	21%	0.205	26%	0.256	C	S	.	.	H	α-helix	trans	-63.1	-45.2	-178.2	-64.5	164.8	0	0	0	110.8	L367 A370 F374 I375 H376	L367-I372 HydrophobicContact CB-CD1 3.95Å; L367-I372 HydrophobicContact CB-CG1 3.76Å; L367-I372 HydrophobicContact CD2-CG1 3.94Å; L367-I372 HydrophobicContact CG-CG1 4.39Å; L367-I372 WeakPolarHBondContact O-CD1 3.11Å; L367-I372 WeakPolarHBondContact O-CG1 3.46Å; A370-I372 PolarHBondContact O-N 2.92Å; I372-F374 VanDerWaalsContact C-N 3.3Å; I372-F374 PolarHBondContact O-N 3.05Å; I372-I375 WeakPolarHBondContact O-CB 3.13Å; I372-I375 PolarHBondContact O-N 2.99Å; I372-I375 VanDerWaalsContact O-N 3.15Å; I372-H376 PolarHBondContact O-CD2 2.99Å; I372-H376 PolarHBondContact O-N 3.48Å
373	S	77.9	Confident	80.8	Confident	18 Å²	18	38.3 Å²	38.3	13%	0.126	24%	0.241	C	C	.	.	H	α-helix	trans	-62.3	-37	-180	-61.4	0	0	0	0	112.5	A370 P371 L377	A370-S373 PolarHBondContact O-N 3.35Å; P371-S373 PolarHBondContact O-N 3.31Å; S373-L377 WeakPolarHBondContact O-CB 3.17Å; S373-L377 PolarHBondContact O-N 2.73Å
374	F	83.3	Confident	81.2	Confident	61 Å²	61	38.6 Å²	38.6	27%	0.268	24%	0.243	S	C	.	.	H	α-helix	trans	-71.1	-33.6	175.4	-72.3	-67.1	0	0	0	112.7	M54 F57 R58 L61 A370 P371 I372 L377 L378	M54-F374 HydrophobicContact CE-CE2 3.61Å; M54-F374 HydrophobicContact CE-CZ 3.76Å; F57-F374 HydrophobicContact CD1-CE1 4.14Å; F57-F374 HydrophobicContact CD1-CZ 4.26Å; F57-F374 HydrophobicContact CE1-CE1 4.11Å; R58-F374 HydrophobicContact CG-CE1 4.21Å; R58-F374 HydrophobicContact CG-CZ 4.06Å; L61-F374 HydrophobicContact CD1-CE1 4.49Å; A370-F374 HydrophobicContact CB-CD2 4.46Å; A370-F374 HydrophobicContact CB-CE2 4.18Å; A370-F374 WeakPolarHBondContact O-CD2 3.26Å; A370-F374 PolarHBondContact O-N 3.48Å; P371-F374 PolarHBondContact O-N 3.01Å; I372-F374 VanDerWaalsContact C-N 3.3Å; I372-F374 PolarHBondContact O-N 3.05Å; F374-L377 HydrophobicContact CD1-CD2 4.15Å; F374-L377 WeakPolarHBondContact O-CB 3.39Å; F374-L377 PolarHBondContact O-N 3.36Å; F374-L378 WeakPolarHBondContact O-CB 3.38Å; F374-L378 PolarHBondContact O-N 3.02Å
375	I	87.8	Confident	81.7	Confident	31 Å²	31	34.9 Å²	34.9	16%	0.159	23%	0.228	C	C	.	.	H	α-helix	trans	-65.4	-44	174.3	-68.8	172.6	0	0	0	110.7	P348 L349 V352 L367 P371 I372 L378 S379	P348-I375 HydrophobicContact CB-CG1 4.42Å; P348-I375 HydrophobicContact CB-CG2 4.15Å; L349-I375 HydrophobicContact CB-CG2 4Å; L349-I375 HydrophobicContact CD1-CG2 4.07Å; V352-I375 HydrophobicContact CB-CD1 4.5Å; V352-I375 HydrophobicContact CG2-CD1 3.64Å; L367-I375 HydrophobicContact CD2-CD1 4.31Å; P371-I375 VanDerWaalsContact O-CG1 3.31Å; P371-I375 WeakPolarHBondContact O-CG1 3.46Å; P371-I375 PolarHBondContact O-N 3.4Å; P371-I375 VanDerWaalsContact O-N 3.08Å; I372-I375 WeakPolarHBondContact O-CB 3.13Å; I372-I375 PolarHBondContact O-N 2.99Å; I372-I375 VanDerWaalsContact O-N 3.15Å; I375-L378 PolarHBondContact O-N 3.31Å; I375-S379 PolarHBondContact O-N 3.5Å; I375-S379 VanDerWaalsContact O-N 3.11Å
376	H	85.8	Confident	82.1	Confident	40 Å²	40	31.6 Å²	31.6	19%	0.185	20%	0.204	C	C	.	.	H	α-helix	trans	-61.7	-44.3	172.2	-73.8	-68.3	0	0	0	111.8	I372 L378 S379 Y380	I372-H376 PolarHBondContact O-CD2 2.99Å; I372-H376 PolarHBondContact O-N 3.48Å; H376-L378 VanDerWaalsContact C-N 3.3Å; H376-L378 PolarHBondContact O-N 2.88Å; H376-S379 PolarHBondContact O-N 2.97Å; H376-S379 VanDerWaalsContact O-N 3.14Å; H376-S379 PolarHBondContact O-OG 3.04Å; H376-Y380 HydrophobicContact CB-CE2 4.1Å; H376-Y380 WeakPolarHBondContact O-CD2 3.11Å; H376-Y380 PolarHBondContact O-N 3.29Å
377	L	87.8	Confident	82.5	Confident	14 Å²	14	28.9 Å²	28.9	7%	0.073	18%	0.181	C	C	.	.	H	α-helix	trans	-57.7	-43.2	176.9	-173.4	80.1	0	0	0	112.3	L61 Y62 I65 S373 F374 S379 Y380 T381	L61-L377 HydrophobicContact CB-CD1 4.07Å; L61-L377 HydrophobicContact CB-CD2 3.78Å; L61-L377 HydrophobicContact CD1-CD2 3.58Å; L61-L377 HydrophobicContact CG-CD2 4.32Å; Y62-L377 HydrophobicContact CD1-CD1 4.28Å; Y62-L377 HydrophobicContact CD2-CD1 3.46Å; Y62-L377 VanDerWaalsContact CD2-CD1 3.46Å; Y62-L377 HydrophobicContact CE1-CD1 4.42Å; Y62-L377 HydrophobicContact CE2-CB 4.19Å; Y62-L377 HydrophobicContact CE2-CD1 3.6Å; Y62-L377 HydrophobicContact CE2-CG 4.49Å; Y62-L377 HydrophobicContact CG-CD1 3.81Å; I65-L377 HydrophobicContact CD1-CD1 3.48Å; I65-L377 VanDerWaalsContact CD1-CD1 3.48Å; I65-L377 HydrophobicContact CD1-CG 3.73Å; S373-L377 WeakPolarHBondContact O-CB 3.17Å; S373-L377 PolarHBondContact O-N 2.73Å; F374-L377 HydrophobicContact CD1-CD2 4.15Å; F374-L377 WeakPolarHBondContact O-CB 3.39Å; F374-L377 PolarHBondContact O-N 3.36Å; L377-S379 VanDerWaalsContact C-N 3.32Å; L377-S379 PolarHBondContact O-N 3.1Å; L377-Y380 PolarHBondContact O-N 3.5Å; L377-T381 PolarHBondContact O-N 3Å; L377-T381 PolarHBondContact O-OG1 3.31Å
378	L	91.1	Very high	83	Confident	62 Å²	62	31.6 Å²	31.6	33%	0.325	20%	0.195	S	C	.	.	H	α-helix	trans	-62.9	-39.4	177.6	-179	57.5	0	0	0	111.5	C345 P348 F374 I375 H376 T381	C345-L378 PolarHBondContact SG-O 3.24Å; P348-L378 HydrophobicContact CB-CD2 4.5Å; P348-L378 HydrophobicContact CG-CD2 3.84Å; F374-L378 WeakPolarHBondContact O-CB 3.38Å; F374-L378 PolarHBondContact O-N 3.02Å; I375-L378 PolarHBondContact O-N 3.31Å; H376-L378 VanDerWaalsContact C-N 3.3Å; H376-L378 PolarHBondContact O-N 2.88Å; L378-T381 VanDerWaalsContact O-CB 3.31Å; L378-T381 WeakPolarHBondContact O-CB 3.41Å; L378-T381 PolarHBondContact O-N 3.31Å
379	S	91.7	Very high	83.9	Confident	0 Å²	0	28 Å²	28	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-64.4	-42.4	173.6	74.9	0	0	0	0	112.3	C345 I375 H376 L377 T381 S382	C345-S379 WeakPolarHBondContact O-CA 3.25Å; I375-S379 PolarHBondContact O-N 3.5Å; I375-S379 VanDerWaalsContact O-N 3.11Å; H376-S379 PolarHBondContact O-N 2.97Å; H376-S379 VanDerWaalsContact O-N 3.14Å; H376-S379 PolarHBondContact O-OG 3.04Å; L377-S379 VanDerWaalsContact C-N 3.32Å; L377-S379 PolarHBondContact O-N 3.1Å; S379-T381 PolarHBondContact O-N 3.32Å; S379-S382 WeakPolarHBondContact O-CB 3.18Å; S379-S382 PolarHBondContact O-N 3.4Å; S379-S382 VanDerWaalsContact O-N 3.13Å; S379-S382 PolarHBondContact O-OG 2.79Å
380	Y	91.8	Very high	84.4	Confident	0 Å²	0	25.8 Å²	25.8	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-66	-23.6	177.8	-65.9	-39.2	0	0	0	113.9	Y62 M104 M109 T112 M135 H376 L377 S382 A383	Y62-Y380 AromaticContact CE1-CD2 3.59Å; Y62-Y380 HydrophobicContact CE1-CD2 3.59Å; Y62-Y380 AromaticContact CE1-CE2 3.66Å; Y62-Y380 HydrophobicContact CE1-CE2 3.66Å; M104-Y380 HydrophobicContact CG-CD1 4.17Å; M104-Y380 HydrophobicContact CG-CE1 4.31Å; M104-Y380 HydrophobicContact SD-CD1 3.92Å; M104-Y380 HydrophobicContact SD-CE1 4.36Å; M109-Y380 HydrophobicContact CE-CD1 4.15Å; M109-Y380 HydrophobicContact CE-CG 4.14Å; M109-Y380 HydrophobicContact CG-CD1 4.2Å; M109-Y380 HydrophobicContact CG-CD2 4.4Å; M109-Y380 HydrophobicContact CG-CE1 4.47Å; M109-Y380 HydrophobicContact CG-CG 4.18Å; T112-Y380 PolarHBondContact OG1-OH 2.86Å; M135-Y380 HydrophobicContact CE-CE1 4.07Å; M135-Y380 WeakPolarHBondContact CE-OH 3.47Å; H376-Y380 HydrophobicContact CB-CE2 4.1Å; H376-Y380 WeakPolarHBondContact O-CD2 3.11Å; H376-Y380 PolarHBondContact O-N 3.29Å; L377-Y380 PolarHBondContact O-N 3.5Å; Y380-S382 PolarHBondContact O-N 3.2Å; Y380-A383 WeakPolarHBondContact O-CB 3.43Å; Y380-A383 PolarHBondContact O-N 2.8Å; Y380-A383 VanDerWaalsContact O-N 3.12Å
381	T	91.9	Very high	85	Confident	36 Å²	36	25.7 Å²	25.7	22%	0.221	14%	0.141	C	C	.	.	H	α-helix	trans	-60.1	-27.6	175.1	-56.3	0	0	0	0	111.5	I65 L377 L378 S379 A383 C384 V385	I65-T381 WeakPolarHBondContact CD1-OG1 3.39Å; L377-T381 PolarHBondContact O-N 3Å; L377-T381 PolarHBondContact O-OG1 3.31Å; L378-T381 VanDerWaalsContact O-CB 3.31Å; L378-T381 WeakPolarHBondContact O-CB 3.41Å; L378-T381 PolarHBondContact O-N 3.31Å; S379-T381 PolarHBondContact O-N 3.32Å; T381-A383 PolarHBondContact O-N 3.28Å; T381-C384 PolarHBondContact O-N 3.47Å; T381-C384 PolarHBondContact O-SG 3.43Å; T381-V385 HydrophobicContact CG2-CG2 3.63Å; T381-V385 WeakPolarHBondContact O-CB 3.03Å; T381-V385 VanDerWaalsContact O-CG2 3.25Å; T381-V385 WeakPolarHBondContact O-CG2 3.27Å; T381-V385 PolarHBondContact O-N 3.2Å
382	S	90.9	Very high	84.8	Confident	14 Å²	14	30.2 Å²	30.2	10%	0.098	16%	0.155	C	C	.	.	H	α-helix	trans	-60.4	-34.7	177	74.3	0	0	0	0	112.6	W346 S379 Y380 N386	W346-S382 VanDerWaalsContact CZ2-OG 3.22Å; W346-S382 WeakPolarHBondContact CZ2-OG 3.15Å; W346-S382 PolarHBondContact NE1-OG 2.94Å; S379-S382 WeakPolarHBondContact O-CB 3.18Å; S379-S382 PolarHBondContact O-N 3.4Å; S379-S382 VanDerWaalsContact O-N 3.13Å; S379-S382 PolarHBondContact O-OG 2.79Å; Y380-S382 PolarHBondContact O-N 3.2Å; S382-N386 PolarHBondContact O-N 3.38Å; S382-N386 PolarHBondContact O-ND2 3.04Å; S382-N386 PolarHBondContact O-OD1 2.94Å
383	A	91.4	Very high	84.1	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-71.5	-31.9	-178.5	0	0	0	0	0	112.9	N73 D101 M104 M109 Y380 T381 P387	N73-A383 PolarHBondContact ND2-O 2.86Å; D101-A383 HydrophobicContact CB-CB 4Å; M104-A383 HydrophobicContact SD-CB 4.21Å; M109-A383 HydrophobicContact CE-CB 4.15Å; Y380-A383 WeakPolarHBondContact O-CB 3.43Å; Y380-A383 PolarHBondContact O-N 2.8Å; Y380-A383 VanDerWaalsContact O-N 3.12Å; T381-A383 PolarHBondContact O-N 3.28Å; A383-P387 WeakPolarHBondContact O-CD 3.39Å
384	C	89.1	Confident	83.5	Confident	6 Å²	6	33.2 Å²	33.2	4%	0.041	17%	0.169	C	C	.	.	H	α-helix	trans	-88.8	-28.1	179.6	72	0	0	0	0	113.1	I65 L68 T381 P387 I388	I65-C384 HydrophobicContact CG2-CB 4.36Å; L68-C384 HydrophobicContact CB-CB 3.85Å; T381-C384 PolarHBondContact O-N 3.47Å; T381-C384 PolarHBondContact O-SG 3.43Å; C384-P387 WeakPolarHBondContact O-CD 3.47Å; C384-I388 WeakPolarHBondContact O-CG1 3.3Å
385	V	89.1	Confident	82.7	Confident	30 Å²	30	33.6 Å²	33.6	18%	0.182	18%	0.176	C	C	.	.	H	α-helix	trans	-74.2	-30.2	-179.6	175.8	0	0	0	0	111.8	L341 T381 I388 I389	L341-V385 HydrophobicContact CD1-CG1 3.54Å; T381-V385 HydrophobicContact CG2-CG2 3.63Å; T381-V385 WeakPolarHBondContact O-CB 3.03Å; T381-V385 VanDerWaalsContact O-CG2 3.25Å; T381-V385 WeakPolarHBondContact O-CG2 3.27Å; T381-V385 PolarHBondContact O-N 3.2Å; V385-I388 WeakPolarHBondContact O-CB 3.2Å; V385-I388 PolarHBondContact O-N 2.99Å; V385-I389 HydrophobicContact CG1-CD1 3.77Å; V385-I389 HydrophobicContact CG1-CG1 3.86Å; V385-I389 WeakPolarHBondContact O-CG1 3.12Å; V385-I389 PolarHBondContact O-N 3.44Å
386	N	85.7	Confident	81.7	Confident	15 Å²	15	41.1 Å²	41.1	8%	0.08	20%	0.203	C	C	.	.	H	α-helix	trans	-50.6	-57.1	177.5	-77.5	-18.5	0	0	0	112.4	L97 D101 S382 I388 I389 Y390	L97-N386 HydrophobicContact CD2-CB 4.49Å; D101-N386 PolarHBondContact OD2-ND2 3.25Å; S382-N386 PolarHBondContact O-N 3.38Å; S382-N386 PolarHBondContact O-ND2 3.04Å; S382-N386 PolarHBondContact O-OD1 2.94Å; N386-I388 VanDerWaalsContact C-N 3.33Å; N386-I388 PolarHBondContact O-N 2.87Å; N386-I389 PolarHBondContact O-N 3.44Å; N386-Y390 HydrophobicContact CB-CE2 4.07Å; N386-Y390 WeakPolarHBondContact O-CD2 3.43Å; N386-Y390 WeakPolarHBondContact O-CE2 3.3Å; N386-Y390 PolarHBondContact O-N 2.95Å; N386-Y390 VanDerWaalsContact O-N 3.16Å
387	P	85.1	Confident	80.9	Confident	3 Å²	3	39.5 Å²	39.5	2%	0.019	20%	0.195	C	C	.	.	H	α-helix	trans	-56.5	-38.8	173	-25.4	30.2	0	0	0	115.8	N73 I76 A383 C384 I389 Y390 C391	N73-P387 VanDerWaalsContact OD1-CG 3.28Å; N73-P387 WeakPolarHBondContact OD1-CG 3.48Å; I76-P387 HydrophobicContact CD1-CB 3.79Å; I76-P387 HydrophobicContact CD1-CG 3.78Å; I76-P387 HydrophobicContact CG1-CB 4.42Å; A383-P387 WeakPolarHBondContact O-CD 3.39Å; C384-P387 WeakPolarHBondContact O-CD 3.47Å; P387-I389 VanDerWaalsContact C-N 3.35Å; P387-Y390 PolarHBondContact O-N 3.39Å; P387-C391 WeakPolarHBondContact O-CB 3.5Å; P387-C391 PolarHBondContact O-N 2.79Å; P387-C391 PolarHBondContact O-SG 3.34Å
388	I	83.9	Confident	80.4	Confident	69 Å²	69	44.3 Å²	44.3	35%	0.354	21%	0.212	S	C	.	.	H	α-helix	trans	-62.8	-46.2	-179.5	-62.8	172.9	0	0	0	109.6	C384 V385 N386 Y390 C391 F392	C384-I388 WeakPolarHBondContact O-CG1 3.3Å; V385-I388 WeakPolarHBondContact O-CB 3.2Å; V385-I388 PolarHBondContact O-N 2.99Å; N386-I388 VanDerWaalsContact C-N 3.33Å; N386-I388 PolarHBondContact O-N 2.87Å; I388-Y390 PolarHBondContact O-N 2.93Å; I388-C391 PolarHBondContact O-N 3.43Å; I388-F392 HydrophobicContact CG2-CD2 3.72Å; I388-F392 HydrophobicContact CG2-CE2 4.07Å; I388-F392 WeakPolarHBondContact O-CB 3.45Å; I388-F392 WeakPolarHBondContact O-CD2 3.48Å; I388-F392 PolarHBondContact O-N 3.28Å
389	I	82.1	Confident	79.6	Confident	13 Å²	13	49 Å²	49	7%	0.067	23%	0.23	C	C	.	.	H	α-helix	trans	-57.5	-50.1	176.9	-65.5	171.7	0	0	0	110.1	M334 V337 I338 L341 V385 N386 P387 M393	M334-I389 HydrophobicContact CG-CG2 3.27Å; M334-I389 HydrophobicContact SD-CG2 4.01Å; V337-I389 HydrophobicContact CG1-CD1 4.3Å; I338-I389 HydrophobicContact CD1-CG2 4.07Å; I338-I389 HydrophobicContact CG1-CD1 3.69Å; I338-I389 HydrophobicContact CG1-CG2 3.97Å; L341-I389 HydrophobicContact CD1-CD1 3.53Å; L341-I389 HydrophobicContact CD1-CG1 4.4Å; V385-I389 HydrophobicContact CG1-CD1 3.77Å; V385-I389 HydrophobicContact CG1-CG1 3.86Å; V385-I389 WeakPolarHBondContact O-CG1 3.12Å; V385-I389 PolarHBondContact O-N 3.44Å; N386-I389 PolarHBondContact O-N 3.44Å; P387-I389 VanDerWaalsContact C-N 3.35Å; I389-M393 VanDerWaalsContact O-CB 3.24Å; I389-M393 WeakPolarHBondContact O-CB 3.4Å; I389-M393 PolarHBondContact O-N 3.48Å
390	Y	76.7	Confident	78.5	Confident	7 Å²	7	49.4 Å²	49.4	3%	0.027	23%	0.233	C	C	.	.	H	α-helix	trans	-67.3	-39.5	-177.9	-58.1	-51.7	0	0	0	112.5	I76 L94 L97 M334 I338 N386 P387 I388 N394	I76-Y390 HydrophobicContact CD1-CD2 4.19Å; L94-Y390 HydrophobicContact CD2-CD1 3.94Å; L94-Y390 HydrophobicContact CD2-CD2 4.2Å; L94-Y390 HydrophobicContact CD2-CE1 3.42Å; L94-Y390 VanDerWaalsContact CD2-CE1 3.42Å; L94-Y390 HydrophobicContact CD2-CE2 3.74Å; L94-Y390 HydrophobicContact CD2-CG 4.32Å; L97-Y390 HydrophobicContact CD2-CE2 3.96Å; L97-Y390 VanDerWaalsContact CD2-OH 3.28Å; L97-Y390 WeakPolarHBondContact CD2-OH 3.38Å; M334-Y390 HydrophobicContact CE-CD1 4.02Å; M334-Y390 HydrophobicContact CE-CE1 4.05Å; M334-Y390 HydrophobicContact SD-CD1 4.38Å; I338-Y390 HydrophobicContact CD1-CE1 3.97Å; N386-Y390 HydrophobicContact CB-CE2 4.07Å; N386-Y390 WeakPolarHBondContact O-CD2 3.43Å; N386-Y390 WeakPolarHBondContact O-CE2 3.3Å; N386-Y390 PolarHBondContact O-N 2.95Å; N386-Y390 VanDerWaalsContact O-N 3.16Å; P387-Y390 PolarHBondContact O-N 3.39Å; I388-Y390 PolarHBondContact O-N 2.93Å; Y390-N394 WeakPolarHBondContact O-CB 3.22Å; Y390-N394 PolarHBondContact O-N 3.28Å; Y390-N394 VanDerWaalsContact O-N 3.14Å
391	C	72.1	Confident	77.7	Confident	27 Å²	27	51 Å²	51	18%	0.182	24%	0.242	C	C	.	.	H	α-helix	trans	-65.3	-48.5	177.7	-77.4	0	0	0	0	112.4	P387 I388 F397 R398	P387-C391 WeakPolarHBondContact O-CB 3.5Å; P387-C391 PolarHBondContact O-N 2.79Å; P387-C391 PolarHBondContact O-SG 3.34Å; I388-C391 PolarHBondContact O-N 3.43Å; C391-F397 WeakPolarHBondContact SG-CE1 3.39Å; C391-R398 VanDerWaalsContact O-CD 3.23Å; C391-R398 WeakPolarHBondContact O-CD 3.35Å; C391-R398 WeakPolarHBondContact O-CG 3.34Å
392	F	68.3	Low	76.9	Confident	148 Å²	148	54.9 Å²	54.9	65%	0.649	26%	0.261	S	S	*	.	H	α-helix	trans	-77.1	-38.4	-175.8	-84	-86.1	0	0	0	112.6	I388	I388-F392 HydrophobicContact CG2-CD2 3.72Å; I388-F392 HydrophobicContact CG2-CE2 4.07Å; I388-F392 WeakPolarHBondContact O-CB 3.45Å; I388-F392 WeakPolarHBondContact O-CD2 3.48Å; I388-F392 PolarHBondContact O-N 3.28Å
393	M	63.8	Low	76.1	Confident	81 Å²	81	57 Å²	57	40%	0.399	28%	0.275	S	S	.	.	H	α-helix	trans	-94.4	-18.8	-169.6	-62.6	-68.1	172.6	0	0	113.9	M334 I389	M334-M393 HydrophobicContact CB-CB 3.96Å; M334-M393 HydrophobicContact CB-CG 4.3Å; M334-M393 HydrophobicContact CG-CB 3.56Å; M334-M393 HydrophobicContact CG-CG 3.99Å; M334-M393 HydrophobicContact SD-CB 3.56Å; M334-M393 VanDerWaalsContact SD-CB 3.56Å; I389-M393 VanDerWaalsContact O-CB 3.24Å; I389-M393 WeakPolarHBondContact O-CB 3.4Å; I389-M393 PolarHBondContact O-N 3.48Å
394	N	65.1	Low	75.2	Confident	40 Å²	40	57.6 Å²	57.6	21%	0.214	28%	0.279	C	S	.	.			trans	-100.1	99.8	177.6	-166.7	-20.8	0	0	0	112.4	Y390 R396 F397 R398	Y390-N394 WeakPolarHBondContact O-CB 3.22Å; Y390-N394 PolarHBondContact O-N 3.28Å; Y390-N394 VanDerWaalsContact O-N 3.14Å; N394-R396 PolarHBondContact O-N 3.18Å; N394-R396 WeakPolarHBondContact OD1-CB 3.27Å; N394-R396 PolarHBondContact OD1-N 3.05Å; N394-R396 VanDerWaalsContact OD1-N 3.1Å; N394-F397 HydrophobicContact CB-CB 3.79Å; N394-F397 WeakPolarHBondContact O-CB 3.39Å; N394-F397 PolarHBondContact O-N 3.24Å; N394-F397 PolarHBondContact OD1-N 3.48Å; N394-R398 PolarHBondContact O-N 3.36Å
395	T	66.1	Low	74.5	Confident	70 Å²	70	62.3 Å²	62.3	43%	0.429	30%	0.299	S	S	.	.	H	α-helix	trans	-58.8	-30.8	178.3	50.9	0	0	0	0	113.6	K399	T395-K399 WeakPolarHBondContact O-CG 3.43Å; T395-K399 PolarHBondContact O-N 3.26Å
396	R	66.4	Low	73.6	Confident	189 Å²	189	63.7 Å²	63.7	71%	0.713	31%	0.314	S	S	*	.	H	α-helix	trans	-71.7	-37.3	175.6	-65.2	-176.6	-179.1	-179.7	0.7	111.4	N394 K399 A400	N394-R396 PolarHBondContact O-N 3.18Å; N394-R396 WeakPolarHBondContact OD1-CB 3.27Å; N394-R396 PolarHBondContact OD1-N 3.05Å; N394-R396 VanDerWaalsContact OD1-N 3.1Å; R396-K399 PolarHBondContact O-N 2.94Å; R396-A400 WeakPolarHBondContact O-CB 3.24Å; R396-A400 PolarHBondContact O-N 2.71Å
397	F	69.1	Low	72.3	Confident	5 Å²	5	65.8 Å²	65.8	2%	0.022	33%	0.329	C	S	.	.	H	α-helix	trans	-64.8	-44.9	175.4	-168.5	-90.2	0	0	0	111	I76 V79 C391 N394 K399 A400 L401	I76-F397 HydrophobicContact CB-CZ 4.47Å; I76-F397 HydrophobicContact CG1-CE2 4.44Å; I76-F397 HydrophobicContact CG1-CZ 3.94Å; V79-F397 HydrophobicContact CB-CE2 4.28Å; V79-F397 HydrophobicContact CB-CZ 4.21Å; V79-F397 HydrophobicContact CG1-CD2 4.41Å; V79-F397 HydrophobicContact CG1-CE2 3.91Å; V79-F397 HydrophobicContact CG1-CZ 4.14Å; V79-F397 HydrophobicContact CG2-CZ 4.5Å; C391-F397 WeakPolarHBondContact SG-CE1 3.39Å; N394-F397 HydrophobicContact CB-CB 3.79Å; N394-F397 WeakPolarHBondContact O-CB 3.39Å; N394-F397 PolarHBondContact O-N 3.24Å; N394-F397 PolarHBondContact OD1-N 3.48Å; F397-K399 VanDerWaalsContact C-N 3.34Å; F397-K399 PolarHBondContact O-N 3Å; F397-A400 WeakPolarHBondContact O-CB 3.39Å; F397-A400 PolarHBondContact O-N 2.83Å; F397-A400 VanDerWaalsContact O-N 3.14Å; F397-L401 HydrophobicContact CD1-CD1 4.46Å; F397-L401 HydrophobicContact CE1-CD1 3.9Å; F397-L401 WeakPolarHBondContact O-CB 3.48Å; F397-L401 PolarHBondContact O-N 2.92Å
398	R	76.3	Confident	71	Confident	116 Å²	116	68.3 Å²	68.3	44%	0.438	35%	0.346	S	S	.	.	H	α-helix	trans	-57.5	-43.5	174.6	-67.8	-166	-77.4	153.2	-6.4	113.2	C391 N394 L401 L402	C391-R398 VanDerWaalsContact O-CD 3.23Å; C391-R398 WeakPolarHBondContact O-CD 3.35Å; C391-R398 WeakPolarHBondContact O-CG 3.34Å; N394-R398 PolarHBondContact O-N 3.36Å; R398-L401 PolarHBondContact O-N 2.95Å; R398-L402 WeakPolarHBondContact O-CB 3.24Å; R398-L402 WeakPolarHBondContact O-CG 3.46Å; R398-L402 PolarHBondContact O-N 2.94Å
399	K	74.7	Confident	69.7	Low	159 Å²	159	68.9 Å²	68.9	69%	0.691	36%	0.355	S	S	*	.	H	α-helix	trans	-63.6	-42.5	175.6	-72.4	-178.1	-179.8	-171.3	0	112	T395 R396 F397 S403	T395-K399 WeakPolarHBondContact O-CG 3.43Å; T395-K399 PolarHBondContact O-N 3.26Å; R396-K399 PolarHBondContact O-N 2.94Å; F397-K399 VanDerWaalsContact C-N 3.34Å; F397-K399 PolarHBondContact O-N 3Å; K399-S403 WeakPolarHBondContact O-CB 3.38Å; K399-S403 PolarHBondContact O-N 2.86Å; K399-S403 PolarHBondContact O-OG 2.85Å
400	A	69.8	Low	68.3	Low	9 Å²	9	76.8 Å²	76.8	7%	0.074	38%	0.384	C	S	.	.	H	α-helix	trans	-63.1	-45.2	176.1	0	0	0	0	0	111.4	V79 M86 R396 F397 S403 T404	V79-A400 HydrophobicContact CG1-CB 3.94Å; M86-A400 HydrophobicContact CE-CB 4.48Å; R396-A400 WeakPolarHBondContact O-CB 3.24Å; R396-A400 PolarHBondContact O-N 2.71Å; F397-A400 WeakPolarHBondContact O-CB 3.39Å; F397-A400 PolarHBondContact O-N 2.83Å; F397-A400 VanDerWaalsContact O-N 3.14Å; A400-S403 WeakPolarHBondContact CA-OG 3.44Å; A400-S403 PolarHBondContact O-N 2.88Å; A400-S403 VanDerWaalsContact O-N 3.17Å; A400-S403 PolarHBondContact O-OG 2.99Å; A400-T404 PolarHBondContact O-N 3.16Å; A400-T404 PolarHBondContact O-OG1 2.8Å; A400-T404 VanDerWaalsContact O-OG1 3.07Å
401	L	74.8	Confident	67.2	Low	34 Å²	34	80.4 Å²	80.4	18%	0.178	40%	0.404	C	S	.	.	H	α-helix	trans	-57.9	-50.4	176.1	-177	146	0	0	0	111.5	L75 F397 R398 S403 T404 F405	L75-L401 HydrophobicContact CD2-CD1 3.57Å; L75-L401 HydrophobicContact CG-CD1 4.14Å; F397-L401 HydrophobicContact CD1-CD1 4.46Å; F397-L401 HydrophobicContact CE1-CD1 3.9Å; F397-L401 WeakPolarHBondContact O-CB 3.48Å; F397-L401 PolarHBondContact O-N 2.92Å; R398-L401 PolarHBondContact O-N 2.95Å; L401-S403 VanDerWaalsContact C-N 3.31Å; L401-S403 PolarHBondContact O-N 3.05Å; L401-T404 PolarHBondContact O-N 3.01Å; L401-F405 HydrophobicContact CD1-CE2 4.36Å; L401-F405 HydrophobicContact CD2-CD2 3.61Å; L401-F405 HydrophobicContact CD2-CE2 3.58Å; L401-F405 HydrophobicContact CG-CD2 3.88Å; L401-F405 HydrophobicContact CG-CE2 3.64Å; L401-F405 WeakPolarHBondContact O-CD2 3.45Å; L401-F405 PolarHBondContact O-N 2.72Å
402	L	75.6	Confident	66.2	Low	118 Å²	118	88.5 Å²	88.5	62%	0.618	43%	0.431	S	S	*	.	H	α-helix	trans	-58.9	-40.4	174.9	-73.3	167.7	0	0	0	112.2	R398 F405 A406	R398-L402 WeakPolarHBondContact O-CB 3.24Å; R398-L402 WeakPolarHBondContact O-CG 3.46Å; R398-L402 PolarHBondContact O-N 2.94Å; L402-F405 PolarHBondContact O-N 3.38Å; L402-A406 VanDerWaalsContact O-CB 3.26Å; L402-A406 WeakPolarHBondContact O-CB 3.38Å; L402-A406 PolarHBondContact O-N 2.81Å
403	S	73.1	Confident	65.4	Low	57 Å²	57	86.9 Å²	86.9	40%	0.399	43%	0.428	S	S	.	.	H	α-helix	trans	-67.5	-36.1	177.2	74.3	0	0	0	0	112.9	K399 A400 L401 C407	K399-S403 WeakPolarHBondContact O-CB 3.38Å; K399-S403 PolarHBondContact O-N 2.86Å; K399-S403 PolarHBondContact O-OG 2.85Å; A400-S403 WeakPolarHBondContact CA-OG 3.44Å; A400-S403 PolarHBondContact O-N 2.88Å; A400-S403 VanDerWaalsContact O-N 3.17Å; A400-S403 PolarHBondContact O-OG 2.99Å; L401-S403 VanDerWaalsContact C-N 3.31Å; L401-S403 PolarHBondContact O-N 3.05Å; S403-C407 VanDerWaalsContact O-CB 3.23Å; S403-C407 WeakPolarHBondContact O-CB 3.33Å; S403-C407 PolarHBondContact O-N 2.99Å
404	T	72	Confident	64.7	Low	13 Å²	13	86.3 Å²	86.3	8%	0.08	43%	0.432	C	S	.	.	H	α-helix	trans	-67.7	-45.7	175.6	-60.5	0	0	0	0	110.4	L82 N83 A400 L401 C407 C408	L82-T404 HydrophobicContact CD1-CG2 3.74Å; N83-T404 PolarHBondContact ND2-OG1 3.15Å; A400-T404 PolarHBondContact O-N 3.16Å; A400-T404 PolarHBondContact O-OG1 2.8Å; A400-T404 VanDerWaalsContact O-OG1 3.07Å; L401-T404 PolarHBondContact O-N 3.01Å; T404-C407 PolarHBondContact O-N 3.19Å; T404-C408 WeakPolarHBondContact O-CB 3.49Å; T404-C408 PolarHBondContact O-N 3.34Å; T404-C408 PolarHBondContact O-SG 3.29Å; T404-C408 VanDerWaalsContact O-SG 3.34Å
405	F	75.1	Confident	64.1	Low	105 Å²	105	92.6 Å²	92.6	46%	0.461	45%	0.452	S	S	.	.	H	α-helix	trans	-63.9	-42.5	174.5	-77.3	-68.7	0	0	0	112.2	L75 L401 L402 C407 C408 C409	L75-F405 HydrophobicContact CD1-CE2 4.1Å; L75-F405 HydrophobicContact CD1-CZ 3.99Å; L401-F405 HydrophobicContact CD1-CE2 4.36Å; L401-F405 HydrophobicContact CD2-CD2 3.61Å; L401-F405 HydrophobicContact CD2-CE2 3.58Å; L401-F405 HydrophobicContact CG-CD2 3.88Å; L401-F405 HydrophobicContact CG-CE2 3.64Å; L401-F405 WeakPolarHBondContact O-CD2 3.45Å; L401-F405 PolarHBondContact O-N 2.72Å; L402-F405 PolarHBondContact O-N 3.38Å; F405-C407 PolarHBondContact O-N 3.37Å; F405-C408 PolarHBondContact O-N 2.69Å; F405-C409 VanDerWaalsContact O-CB 3.26Å; F405-C409 WeakPolarHBondContact O-CB 3.32Å; F405-C409 PolarHBondContact O-N 2.85Å; F405-C409 PolarHBondContact O-SG 2.8Å
406	A	70.1	Confident	63.4	Low	60 Å²	60	99 Å²	99	50%	0.496	47%	0.469	S	S	.	.	H	α-helix	trans	-62.4	-40.4	175.5	0	0	0	0	0	112.3	L402 R410	L402-A406 VanDerWaalsContact O-CB 3.26Å; L402-A406 WeakPolarHBondContact O-CB 3.38Å; L402-A406 PolarHBondContact O-N 2.81Å; A406-R410 WeakPolarHBondContact O-CB 3.41Å; A406-R410 PolarHBondContact O-N 3.4Å
407	C	58.3	Low	62.8	Low	59 Å²	59	94.6 Å²	94.6	40%	0.399	46%	0.458	S	S	.	.	H	α-helix	trans	-71.5	-39.1	177.1	-168.2	0	0	0	0	112.2	S403 T404 F405 R410 N411	S403-C407 VanDerWaalsContact O-CB 3.23Å; S403-C407 WeakPolarHBondContact O-CB 3.33Å; S403-C407 PolarHBondContact O-N 2.99Å; T404-C407 PolarHBondContact O-N 3.19Å; F405-C407 PolarHBondContact O-N 3.37Å; C407-R410 PolarHBondContact O-N 2.79Å; C407-N411 VanDerWaalsContact O-CB 3.23Å; C407-N411 WeakPolarHBondContact O-CB 3.38Å; C407-N411 PolarHBondContact O-N 2.82Å
408	C	58.7	Low	61.7	Low	55 Å²	55	101.3 Å²	101.3	37%	0.372	48%	0.483	S	S	.	.	H	α-helix	trans	-67.4	-39.9	174.3	-74.3	0	0	0	0	112.1	T404 F405 R412	T404-C408 WeakPolarHBondContact O-CB 3.49Å; T404-C408 PolarHBondContact O-N 3.34Å; T404-C408 PolarHBondContact O-SG 3.29Å; T404-C408 VanDerWaalsContact O-SG 3.34Å; F405-C408 PolarHBondContact O-N 2.69Å; C408-R412 WeakPolarHBondContact O-CB 3.45Å; C408-R412 WeakPolarHBondContact O-CG 3.09Å; C408-R412 PolarHBondContact O-N 2.91Å
409	C	55.3	Low	60.3	Low	82 Å²	82	102.9 Å²	102.9	55%	0.554	49%	0.49	S	S	*	.	H	α-helix	trans	-65.9	-43.2	173.2	-69.4	0	0	0	0	111.1	F405 R412 L413	F405-C409 VanDerWaalsContact O-CB 3.26Å; F405-C409 WeakPolarHBondContact O-CB 3.32Å; F405-C409 PolarHBondContact O-N 2.85Å; F405-C409 PolarHBondContact O-SG 2.8Å; C409-R412 PolarHBondContact O-N 2.88Å; C409-L413 WeakPolarHBondContact O-CB 3.46Å; C409-L413 PolarHBondContact O-N 3.02Å
410	R	53.5	Low	58.7	Low	179 Å²	179	104.4 Å²	104.4	68%	0.675	49%	0.491	S	S	*	.	H	α-helix	trans	-68	-37.4	177	-163.3	164.3	74.8	178.1	6	112.5	A406 C407 L413 C414	A406-R410 WeakPolarHBondContact O-CB 3.41Å; A406-R410 PolarHBondContact O-N 3.4Å; C407-R410 PolarHBondContact O-N 2.79Å; R410-L413 PolarHBondContact O-N 3.47Å; R410-C414 VanDerWaalsContact O-CB 3.24Å; R410-C414 WeakPolarHBondContact O-CB 3.22Å; R410-C414 PolarHBondContact O-N 3.33Å; R410-C414 PolarHBondContact O-SG 3.43Å
411	N	53.2	Low	57.4	Low	83 Å²	83	113.2 Å²	113.2	44%	0.444	52%	0.522	S	S	.	.	H	α-helix	trans	-72.8	-31	174.8	-83.2	-10.4	0	0	0	113.1	C407 R415	C407-N411 VanDerWaalsContact O-CB 3.23Å; C407-N411 WeakPolarHBondContact O-CB 3.38Å; C407-N411 PolarHBondContact O-N 2.82Å; N411-R415 VanDerWaalsContact O-CB 3.27Å; N411-R415 WeakPolarHBondContact O-CB 3.5Å; N411-R415 WeakPolarHBondContact O-CG 3.21Å; N411-R415 PolarHBondContact O-N 2.85Å
412	R	51.5	Low	55.7	Low	196 Å²	196	117.6 Å²	117.6	74%	0.74	54%	0.536	S	S	*	.	H	α-helix	trans	-70.2	-39.7	170.2	-75.9	-175.2	-160.8	-157.9	6	111.5	C408 C409 R416	C408-R412 WeakPolarHBondContact O-CB 3.45Å; C408-R412 WeakPolarHBondContact O-CG 3.09Å; C408-R412 PolarHBondContact O-N 2.91Å; C409-R412 PolarHBondContact O-N 2.88Å; R412-R416 WeakPolarHBondContact O-CB 3.37Å; R412-R416 PolarHBondContact O-N 3.27Å
413	L	51.3	Low	54	Low	115 Å²	115	122.3 Å²	122.3	60%	0.602	55%	0.546	S	S	*	.	H	α-helix	trans	-67.5	-45.3	175.2	-138.7	80	0	0	0	111.2	C409 R410 R416 I417	C409-L413 WeakPolarHBondContact O-CB 3.46Å; C409-L413 PolarHBondContact O-N 3.02Å; R410-L413 PolarHBondContact O-N 3.47Å; L413-R416 PolarHBondContact O-N 3.06Å; L413-I417 HydrophobicContact CG-CD1 4.39Å; L413-I417 WeakPolarHBondContact O-CB 3.35Å; L413-I417 WeakPolarHBondContact O-CD1 3.48Å; L413-I417 VanDerWaalsContact O-CG1 3.22Å; L413-I417 WeakPolarHBondContact O-CG1 3.45Å; L413-I417 PolarHBondContact O-N 2.95Å
414	C	49.4	Very low	52.6	Low	69 Å²	69	127 Å²	127	47%	0.466	56%	0.562	S	S	.	*	H	α-helix	trans	-65.6	-37.2	175	-73.4	0	0	0	0	112.3	R410 W418	R410-C414 VanDerWaalsContact O-CB 3.24Å; R410-C414 WeakPolarHBondContact O-CB 3.22Å; R410-C414 PolarHBondContact O-N 3.33Å; R410-C414 PolarHBondContact O-SG 3.43Å; C414-W418 WeakPolarHBondContact O-CB 3.27Å; C414-W418 PolarHBondContact O-N 2.99Å
415	R	52.5	Low	51.2	Low	172 Å²	172	129.3 Å²	129.3	65%	0.649	59%	0.588	S	S	*	*	H	α-helix	trans	-65.7	-43	171	-84.1	-176.6	-150.4	-134.6	0	111.9	N411 W418 W419	N411-R415 VanDerWaalsContact O-CB 3.27Å; N411-R415 WeakPolarHBondContact O-CB 3.5Å; N411-R415 WeakPolarHBondContact O-CG 3.21Å; N411-R415 PolarHBondContact O-N 2.85Å; R415-W418 PolarHBondContact O-N 3.43Å; R415-W419 WeakPolarHBondContact O-CB 3.48Å; R415-W419 PolarHBondContact O-N 3.05Å
416	R	50.9	Low	49.5	Very low	205 Å²	205	131.6 Å²	131.6	77%	0.774	60%	0.6	S	S	*	*	H	α-helix	trans	-62.3	-42.7	175.9	-92.2	-173.1	-178.9	-179.8	0.2	112.2	R412 L413 R420	R412-R416 WeakPolarHBondContact O-CB 3.37Å; R412-R416 PolarHBondContact O-N 3.27Å; L413-R416 PolarHBondContact O-N 3.06Å; R416-R420 WeakPolarHBondContact O-CB 3.36Å; R416-R420 PolarHBondContact O-N 2.95Å
417	I	53.3	Low	48	Very low	96 Å²	96	136.1 Å²	136.1	49%	0.492	62%	0.616	S	S	.	*	H	α-helix	trans	-68.1	-40.2	178	-66	164.5	0	0	0	110.7	L413 R420 R421	L413-I417 HydrophobicContact CG-CD1 4.39Å; L413-I417 WeakPolarHBondContact O-CB 3.35Å; L413-I417 WeakPolarHBondContact O-CD1 3.48Å; L413-I417 VanDerWaalsContact O-CG1 3.22Å; L413-I417 WeakPolarHBondContact O-CG1 3.45Å; L413-I417 PolarHBondContact O-N 2.95Å; I417-R420 PolarHBondContact O-N 3.45Å; I417-R421 WeakPolarHBondContact O-CB 3.37Å; I417-R421 PolarHBondContact O-N 3.24Å
418	W	46	Very low	46.8	Very low	145 Å²	145	136.1 Å²	136.1	55%	0.549	63%	0.626	S	S	.	*	H	α-helix	trans	-67.5	-40.9	177	-166.4	84.7	0	0	0	112.4	C414 R415 R422	C414-W418 WeakPolarHBondContact O-CB 3.27Å; C414-W418 PolarHBondContact O-N 2.99Å; R415-W418 PolarHBondContact O-N 3.43Å; W418-R422 WeakPolarHBondContact O-CB 3.37Å; W418-R422 PolarHBondContact O-N 3.45Å
419	W	46.3	Very low	45.9	Very low	150 Å²	150	141.2 Å²	141.2	57%	0.568	65%	0.648	S	S	*	*	H	α-helix	trans	-68.3	-33.4	173.7	-81	111.7	0	0	0	113	R415 R423	R415-W419 WeakPolarHBondContact O-CB 3.48Å; R415-W419 PolarHBondContact O-N 3.05Å; W419-R423 PolarHBondContact O-N 3.4Å
420	R	42.7	Very low	44.7	Very low	190 Å²	190	145 Å²	145	72%	0.717	66%	0.663	S	S	*	*	H	α-helix	trans	-69.2	-44.2	174.6	-157.9	179.3	-143.7	-175.4	4.1	111.5	R416 I417 R422 R423 E424	R416-R420 WeakPolarHBondContact O-CB 3.36Å; R416-R420 PolarHBondContact O-N 2.95Å; I417-R420 PolarHBondContact O-N 3.45Å; R420-R422 VanDerWaalsContact C-N 3.32Å; R420-R422 PolarHBondContact O-N 3.42Å; R420-R423 PolarHBondContact O-N 3.36Å; R420-E424 PolarHBondContact O-N 3.36Å
421	R	41.7	Very low	43.6	Very low	195 Å²	195	140.5 Å²	140.5	74%	0.736	66%	0.664	S	S	*	*	H	α-helix	trans	-68.1	-27.9	177.1	-171.4	175.4	-87.8	178.8	-8.6	113.1	I417 G425	I417-R421 WeakPolarHBondContact O-CB 3.37Å; I417-R421 PolarHBondContact O-N 3.24Å; R421-G425 PolarHBondContact O-N 3.27Å
422	R	38.3	Very low	42.6	Very low	126 Å²	126	143 Å²	143	48%	0.475	68%	0.682	S	S	.	*	H	α-helix	trans	-75.9	-29.9	174.6	-161.2	173.2	-174.4	173.2	2.9	112.8	W418 R420 G425	W418-R422 WeakPolarHBondContact O-CB 3.37Å; W418-R422 PolarHBondContact O-N 3.45Å; R420-R422 VanDerWaalsContact C-N 3.32Å; R420-R422 PolarHBondContact O-N 3.42Å; R422-G425 PolarHBondContact O-N 3.35Å
423	R	40	Very low	41.5	Very low	216 Å²	216	139 Å²	139	82%	0.815	68%	0.684	S	S	*	*	H	α-helix	trans	-77.8	-20.1	177.8	-151.1	-177.6	-78.5	-173.1	-7.5	113.3	W419 R420	W419-R423 PolarHBondContact O-N 3.4Å; R420-R423 PolarHBondContact O-N 3.36Å
424	E	45.4	Very low	40.5	Very low	157 Å²	157	142.8 Å²	142.8	73%	0.734	70%	0.701	S	S	*	*	S	Bend	trans	-94.9	-4	172.9	-72.9	170.8	179.5	0	0	113	R420	R420-E424 PolarHBondContact O-N 3.36Å
425	G	41.9	Very low	39.6	Very low	61 Å²	61	142.6 Å²	142.6	63%	0.629	71%	0.71	S	S	*	*	S	Bend	trans	-112.9	9.6	-173.8	0	0	0	0	0	115.2	R421 R422	R421-G425 PolarHBondContact O-N 3.27Å; R422-G425 PolarHBondContact O-N 3.35Å
426	E	39.4	Very low	38.6	Very low	152 Å²	152	141.1 Å²	141.1	71%	0.71	72%	0.721	S	S	*	*			trans	-107.7	8.6	-179.6	-120.3	170.6	136.3	0	0	113.5
427	D	37.8	Very low	37.5	Very low	155 Å²	155	136.8 Å²	136.8	83%	0.829	72%	0.722	S	S	*	*	S	Bend	trans	-93.8	94.7	160.9	-68.5	-27.7	0	0	0	107.9	I429	D427-I429 PolarHBondContact O-N 3.4Å
428	G	34.3	Very low	36.7	Very low	59 Å²	59	140.9 Å²	140.9	61%	0.608	74%	0.741	S	S	*	*			trans	-46.1	128.4	179.2	0	0	0	0	0	112.2
429	I	38.9	Very low	36.1	Very low	163 Å²	163	140.1 Å²	140.1	84%	0.836	75%	0.752	S	S	*	*				56.7	95	86.3	-57.9	165.2	0	0	0	110.3	D427	D427-I429 PolarHBondContact O-N 3.4Å
430	N	29.9	Very low	35.3	Very low	162 Å²	162	139.2 Å²	139.2	87%	0.866	76%	0.764	S	S	*	*			trans	-139	127.9	144.9	-91.4	-20.8	0	0	0	109.5
431	A	31.8	Very low	34.5	Very low	84 Å²	84	135.3 Å²	135.3	69%	0.694	77%	0.765	S	S	*	*			trans	72.9	108.8	148.2	0	0	0	0	0	120.3
432	T	31.6	Very low	34.2	Very low	134 Å²	134	134.1 Å²	134.1	82%	0.822	77%	0.77	S	S	*	*			trans	55	115.1	131.3	38.4	0	0	0	0	121.7
433	S	28.2	Very low	33.8	Very low	113 Å²	113	133.3 Å²	133.3	79%	0.79	78%	0.783	S	S	*	*			trans	144	110.2	131.8	66	0	0	0	0	108.8
434	M	30.3	Very low	33.4	Very low	195 Å²	195	131.1 Å²	131.1	96%	0.961	78%	0.78	S	S	*	*				66.1	114.9	90.2	-144.4	-173.7	177.6	0	0	113.3
435	G	30.6	Very low	32.6	Very low	64 Å²	64	134 Å²	134	66%	0.66	79%	0.79	S	S	*	*			trans	107.4	127	148.1	0	0	0	0	0	117.9
436	T	30.8	Very low	32.1	Very low	142 Å²	142	135.5 Å²	135.5	87%	0.871	79%	0.791	S	S	*	*			trans	72.7	92.5	146.6	27.5	0	0	0	0	119.5
437	S	28.7	Very low	31.6	Very low	114 Å²	114	139.3 Å²	139.3	80%	0.797	80%	0.801	S	S	*	*				165.4	107	95.1	54.9	0	0	0	0	110.8
438	M	35.6	Very low	31.4	Very low	181 Å²	181	138.2 Å²	138.2	89%	0.892	80%	0.8	S	S	*	*			trans	-68.9	163.4	143.7	-80	-172	178	0	0	108.8
439	V	33.3	Very low	31.2	Very low	130 Å²	130	141.9 Å²	141.9	79%	0.788	81%	0.811	S	S	*	*			trans	112.2	112.4	-178.4	174.7	0	0	0	0	106.6
440	T	31.2	Very low	30.7	Very low	131 Å²	131	140.4 Å²	140.4	80%	0.804	81%	0.809	S	S	*	*			cis	-171.5	157	29	13.9	0	0	0	0	104.4
441	S	25.6	Very low	30.7	Very low	107 Å²	107	137.9 Å²	137.9	75%	0.748	80%	0.804	S	S	*	*			cis	-166.9	136.9	27.7	178.6	0	0	0	0	107.7
442	M	34	Very low	30.7	Very low	171 Å²	171	140.3 Å²	140.3	84%	0.842	81%	0.81	S	S	*	*			trans	-100.6	138.2	159.9	-80.5	-148.4	73.9	0	0	109.6
443	S	29.9	Very low	30.8	Very low	108 Å²	108	140.3 Å²	140.3	76%	0.755	81%	0.81	S	S	*	*			trans	-155.7	103.7	145.1	57	0	0	0	0	108.3
444	K	32.7	Very low	30.9	Very low	171 Å²	171	138.6 Å²	138.6	74%	0.743	81%	0.81	S	S	*	*				50.1	113.9	85.3	-96.2	-176.2	179.2	168.9	0	115.5
445	F	29.2	Very low	31.2	Very low	216 Å²	216	135.5 Å²	135.5	95%	0.947	80%	0.802	S	S	*	*				-148.7	126.1	126.3	-113.2	-80.6	0	0	0	110.5
446	S	29.3	Very low	31.3	Very low	93 Å²	93	142.5 Å²	142.5	65%	0.65	84%	0.839	S	S	*	*			trans	-77.9	158	-175.5	-62.5	0	0	0	0	113.6
447	Y	30.8	Very low	31.4	Very low	232 Å²	232	142.5 Å²	142.5	91%	0.91	84%	0.837	S	S	*	*			trans	-120.4	123.2	151.3	-84.7	-85.8	0	0	0	109.2
448	T	32.2	Very low	31.5	Very low	133 Å²	133	144 Å²	144	82%	0.816	84%	0.839	S	S	*	*			trans	-75.1	137.4	171.7	33.6	0	0	0	0	110.5
449	T	30.9	Very low	31.3	Very low	135 Å²	135	141.9 Å²	141.9	83%	0.828	84%	0.836	S	S	*	*			trans	-117.5	120.2	164.4	-9.5	0	0	0	0	106.9
450	V	28.9	Very low	31.2	Very low	132 Å²	132	142.6 Å²	142.6	80%	0.8	84%	0.839	S	S	*	*			trans	-88.9	115	172.6	176.2	0	0	0	0	107.1
451	S	29.4	Very low	31.2	Very low	109 Å²	109	143.4 Å²	143.4	76%	0.762	84%	0.842	S	S	*	*			trans	-118.8	111	163.6	-71.2	0	0	0	0	107.3
452	T	31.4	Very low	31.5	Very low	135 Å²	135	145.8 Å²	145.8	83%	0.828	85%	0.848	S	S	*	*			trans	-82.2	115.2	168.9	35.5	0	0	0	0	109.2
453	V	33.9	Very low	31.4	Very low	134 Å²	134	144 Å²	144	81%	0.812	85%	0.848	S	S	*	*			trans	-106.8	124.9	159.2	178.1	0	0	0	0	105.8
454	G	30.1	Very low	31.5	Very low	78 Å²	78	146.8 Å²	146.8	80%	0.804	86%	0.855	S	S	*	*			trans	-131.5	113.7	170	0	0	0	0	0	108.7
455	T	36.9	Very low	31.4	Very low	129 Å²	129	144.8 Å²	144.8	79%	0.791	87%	0.865	S	S	*	*			trans	-96.8	122.8	164.5	41.2	0	0	0	0	108.6
456	C	33.5	Very low	31.6	Very low	211 Å²	211	138.3 Å²	138.3	100%	1.426	86%	0.857	S	S	*	*			trans	-162	0	133	-94.4	0	0	0	0	106.8

Retrieved 456 of 456 residues in 184.9 ms (Link to these results)

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