A0A087X522_POEFO Loading...

Carboxypeptidase M

AlphaFold DB , UniProt , Accession A0A087X522, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 454 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40Very low39.6Very low252 Ų252146.3 Ų146.3100%1.24181%0.813SS**  099.90-60-173.290.700106.7
2S34.7Very low39.9Very low119 Ų119147.1 Ų147.183%0.83281%0.813SS**  trans-114117.2-179.8-169.70000107.2
3S38.3Very low40Very low117 Ų117144.3 Ų144.382%0.81880%0.803SS**  trans-95.6110.1-178.7-166.80000107.9
4S39.6Very low40.3Very low100 Ų100141.2 Ų141.270%0.69979%0.792SS**  trans-86.4108.3172-62.60000109.2F6S4-F6 PolarHBondContact O-N 3.41Å
5L42.4Very low41Very low146 Ų146138.3 Ų138.376%0.76478%0.779SS**  trans-76.3107.6171.7-164.975.4000108.4L7L5-L7 HydrophobicContact CD2-CD1 4.2Å; L5-L7 PolarHBondContact O-N 3.23Å
6F42.1Very low41.8Very low192 Ų192138.9 Ų138.984%0.84278%0.779SS**  trans-74.9102.1168.1-92.4-88.5000108.6S4 L8S4-F6 PolarHBondContact O-N 3.41Å; F6-L8 PolarHBondContact O-N 3.31Å
7L39.7Very low43.4Very low135 Ų135140.6 Ų140.671%0.70778%0.782SS**  trans-73106.9162.1-97.7111.7000108.3L5 L9L5-L7 HydrophobicContact CD2-CD1 4.2Å; L5-L7 PolarHBondContact O-N 3.23Å; L7-L9 PolarHBondContact O-N 3.12Å; L7-L9 VanDerWaalsContact O-N 3.12Å
8L40.7Very low46.1Very low165 Ų165133.9 Ų133.986%0.86474%0.744SS**  trans-67.6101.8157.6-101.795.6000107.4F6 S10F6-L8 PolarHBondContact O-N 3.31Å; L8-S10 PolarHBondContact O-N 3.08Å; L8-S10 VanDerWaalsContact O-N 3.08Å
9L38.2Very low48.6Very low140 Ų140132.6 Ų132.673%0.73373%0.732SS**  trans-71.197.1164.3-133.685.4000107L7 L11L7-L9 PolarHBondContact O-N 3.12Å; L7-L9 VanDerWaalsContact O-N 3.12Å; L9-L11 VanDerWaalsContact C-N 3.33Å; L9-L11 PolarHBondContact O-N 2.98Å
10S41.5Very low50.9Low97 Ų97129.4 Ų129.468%0.67871%0.71SS**  trans-63.998.7161.650.70000107.3L8 L12L8-S10 PolarHBondContact O-N 3.08Å; L8-S10 VanDerWaalsContact O-N 3.08Å; S10-L12 VanDerWaalsContact C-N 3.27Å; S10-L12 PolarHBondContact O-N 2.9Å
11L38.7Very low53.1Low146 Ų146127 Ų12776%0.76469%0.69SS**  trans-60.794.6166.2-80.4152.7000107.1L9 V13L9-L11 VanDerWaalsContact C-N 3.33Å; L9-L11 PolarHBondContact O-N 2.98Å; L11-V13 PolarHBondContact O-N 2.87Å
12L42.4Very low55.8Low156 Ų156116.9 Ų116.982%0.81764%0.639SS**  trans-62.693153.7-91.494.5000105.2S10 P14S10-L12 VanDerWaalsContact C-N 3.27Å; S10-L12 PolarHBondContact O-N 2.9Å; L12-P14 VanDerWaalsContact O-CD 3.25Å; L12-P14 WeakPolarHBondContact O-CD 3.25Å; L12-P14 VanDerWaalsContact O-N 3.17Å
13V41.9Very low58.8Low111 Ų111111.9 Ų111.967%0.67360%0.602SS**  trans-61.9115162.8-177.50000104.4L11 T15L11-V13 PolarHBondContact O-N 2.87Å; V13-T15 PolarHBondContact O-N 3.08Å; V13-T15 VanDerWaalsContact O-N 3.08Å
14P44.2Very low61.6Low101 Ų101109.7 Ų109.766%0.65658%0.581SS**  trans-57.6124.3172.624.8-30.4000105.7L12 L16L12-P14 VanDerWaalsContact O-CD 3.25Å; L12-P14 WeakPolarHBondContact O-CD 3.25Å; L12-P14 VanDerWaalsContact O-N 3.17Å; P14-L16 PolarHBondContact O-N 2.65Å
15T50.4Low64.3Low97 Ų97105.6 Ų105.660%0.59555%0.552SS**  trans-51.6105.517344.70000106.9V13 M17V13-T15 PolarHBondContact O-N 3.08Å; V13-T15 VanDerWaalsContact O-N 3.08Å; T15-M17 PolarHBondContact O-N 3.11Å
16L53.7Low66.9Low149 Ų149107 Ų10778%0.7855%0.547SS*.  trans-55.1114.9175.5-110.889.6000105.9P14 L18P14-L16 PolarHBondContact O-N 2.65Å; L16-L18 PolarHBondContact O-N 3.16Å
17M69.3Low69.6Low167 Ų167100.3 Ų100.382%0.82352%0.518SS*.PPolyproline II helixtrans-58.7128.4169.6-65.5-173.88400106.7T15 E19T15-M17 PolarHBondContact O-N 3.11Å; M17-E19 PolarHBondContact O-N 3Å; M17-E19 VanDerWaalsContact O-N 3.11Å
18L91.2Very high72.4Confident21 Ų2194.1 Ų94.111%0.1149%0.486CS..PPolyproline II helixtrans-60.6117.3178.7179.870.2000108.9L16 H23 Y31 L95 Q96 A99L16-L18 PolarHBondContact O-N 3.16Å; L18-H23 WeakPolarHBondContact CD1-NE2 3.48Å; L18-Y31 HydrophobicContact CB-CE2 4.32Å; L18-Y31 HydrophobicContact CD1-CD2 3.82Å; L18-Y31 HydrophobicContact CD1-CE2 3.81Å; L18-Y31 HydrophobicContact CD1-CG 4.29Å; L18-Y31 HydrophobicContact CD2-CE1 4.43Å; L18-Y31 HydrophobicContact CD2-CE2 4.37Å; L18-Y31 HydrophobicContact CG-CE2 4.39Å; L18-L95 HydrophobicContact CD2-CB 3.44Å; L18-L95 VanDerWaalsContact CD2-CB 3.44Å; L18-Q96 HydrophobicContact CD2-CG 4.31Å; L18-Q96 PolarHBondContact O-NE2 3.11Å; L18-A99 HydrophobicContact CB-CB 4.39Å
19E93.6Very high75.1Confident108 Ų10890 Ų9051%0.50546%0.462SS..PPolyproline II helixtrans-65.2146.9-175.4-65.3179.5165.400111.8M17 R21 H23 Q96M17-E19 PolarHBondContact O-N 3Å; M17-E19 VanDerWaalsContact O-N 3.11Å; E19-R21 VanDerWaalsContact C-N 3.34Å; E19-R21 HydrophobicContact CB-CG 4.13Å; E19-R21 PolarHBondContact O-N 2.91Å; E19-R21 WeakPolarHBondContact OE2-CD 3.42Å; E19-R21 IonicContact OE2-NE 3.11Å; E19-R21 PolarHBondContact OE2-NE 3.13Å; E19-H23 PolarHBondContact O-CE1 3.33Å; E19-H23 VanDerWaalsContact O-CE1 3.31Å; E19-Q96 PolarHBondContact O-NE2 3.47Å
20F96.3Very high77.9Confident69 Ų6988.2 Ų88.230%0.30345%0.45SS..SBendtrans-81.582.9170.9-76.4-75.9000110.5Q96 L301 P302 W305F20-Q96 HydrophobicContact CD1-CG 4.3Å; F20-Q96 HydrophobicContact CE1-CG 3.67Å; F20-Q96 HydrophobicContact CZ-CG 4.21Å; F20-L301 HydrophobicContact CB-CB 4.17Å; F20-L301 HydrophobicContact CD1-CB 4.02Å; F20-P302 HydrophobicContact CB-CG 3.73Å; F20-P302 HydrophobicContact CD1-CB 4.48Å; F20-P302 HydrophobicContact CD1-CG 4.29Å; F20-P302 HydrophobicContact CD2-CB 4.08Å; F20-P302 HydrophobicContact CD2-CG 3.89Å; F20-P302 HydrophobicContact CE2-CB 4.33Å; F20-P302 HydrophobicContact CG-CB 4.16Å; F20-P302 HydrophobicContact CG-CG 3.71Å; F20-W305 HydrophobicContact CE1-CB 3.52Å; F20-W305 AromaticContact CE1-CD1 3.97Å; F20-W305 AromaticContact CE1-CG 3.78Å; F20-W305 HydrophobicContact CE1-CG 3.78Å; F20-W305 HydrophobicContact CZ-CB 3.98Å; F20-W305 AromaticContact CZ-CD1 3.52Å; F20-W305 AromaticContact CZ-CG 3.82Å; F20-W305 HydrophobicContact CZ-CG 3.82Å
21R95.6Very high80.6Confident78 Ų7885.6 Ų85.629%0.29443%0.425SS..SBendtrans-150.9171.1174.465.1177.5179.885.1-7.4111.1E19 H23 E27E19-R21 VanDerWaalsContact C-N 3.34Å; E19-R21 HydrophobicContact CB-CG 4.13Å; E19-R21 PolarHBondContact O-N 2.91Å; E19-R21 WeakPolarHBondContact OE2-CD 3.42Å; E19-R21 IonicContact OE2-NE 3.11Å; E19-R21 PolarHBondContact OE2-NE 3.13Å; R21-H23 PolarHBondContact O-CE1 3.37Å; R21-H23 PolarHBondContact O-ND1 3.49Å; R21-E27 IonicContact CZ-OE1 3.54Å; R21-E27 IonicContact CZ-OE2 2.82Å; R21-E27 VanDerWaalsContact NH1-CD 3.29Å; R21-E27 IonicContact NH1-OE1 3.68Å; R21-E27 PolarHBondContact NH1-OE1 3.09Å; R21-E27 IonicContact NH1-OE2 3.7Å; R21-E27 PolarHBondContact NH1-OE2 3.39Å; R21-E27 IonicContact NH2-OE1 2.71Å; R21-E27 PolarHBondContact NH2-OE1 3.3Å; R21-E27 IonicContact NH2-OE2 2.96Å
22Y97Very high83.5Confident40 Ų4078.6 Ų78.616%0.15739%0.389CS..  trans-73.4128.3168.3-61.1-58.5000110V88 V92 F295 P296 P298 L301Y22-V88 HydrophobicContact CD1-CB 4.4Å; Y22-V88 HydrophobicContact CD1-CG2 4.2Å; Y22-V88 HydrophobicContact CE1-CB 3.98Å; Y22-V88 HydrophobicContact CE1-CG2 3.39Å; Y22-V92 HydrophobicContact CD1-CG2 3.86Å; Y22-V92 HydrophobicContact CE1-CG2 3.92Å; Y22-F295 HydrophobicContact CD1-CE1 4.24Å; Y22-F295 HydrophobicContact CD2-CD1 4.46Å; Y22-F295 AromaticContact CD2-CE1 3.55Å; Y22-F295 HydrophobicContact CD2-CE1 3.55Å; Y22-F295 HydrophobicContact CD2-CZ 4.27Å; Y22-F295 HydrophobicContact CE1-CD1 4.44Å; Y22-F295 HydrophobicContact CE1-CE1 4.04Å; Y22-F295 AromaticContact CE2-CD1 3.76Å; Y22-F295 HydrophobicContact CE2-CD1 3.76Å; Y22-F295 AromaticContact CE2-CE1 3.28Å; Y22-F295 HydrophobicContact CE2-CE1 3.28Å; Y22-F295 HydrophobicContact CE2-CZ 4.34Å; Y22-F295 HydrophobicContact CG-CE1 4.02Å; Y22-F295 HydrophobicContact CG-CZ 4.37Å; Y22-F295 AromaticContact CZ-CD1 3.74Å; Y22-F295 AromaticContact CZ-CE1 3.53Å; Y22-P296 WeakPolarHBondContact OH-CD 3.45Å; Y22-P296 PolarHBondContact OH-O 2.96Å; Y22-P298 HydrophobicContact CD2-CG 3.96Å; Y22-P298 HydrophobicContact CE2-CG 3.8Å; Y22-L301 HydrophobicContact CE1-CD1 4.21Å; Y22-L301 HydrophobicContact CE1-CD2 4.15Å
23H97.2Very high86.2Confident15 Ų1574.6 Ų74.67%0.06937%0.371CS..  trans-107.1126.8176.5-66.466.1000108.1L18 E19 R21 E27 I28 R91 L95L18-H23 WeakPolarHBondContact CD1-NE2 3.48Å; E19-H23 PolarHBondContact O-CE1 3.33Å; E19-H23 VanDerWaalsContact O-CE1 3.31Å; R21-H23 PolarHBondContact O-CE1 3.37Å; R21-H23 PolarHBondContact O-ND1 3.49Å; H23-E27 VanDerWaalsContact CA-OE2 3.29Å; H23-E27 WeakPolarHBondContact CA-OE2 3.48Å; H23-E27 HydrophobicContact CB-CB 4.06Å; H23-I28 HydrophobicContact CB-CG1 3.87Å; H23-R91 PolarHBondContact O-NE 2.95Å; H23-R91 PolarHBondContact O-NH2 3.46Å; H23-L95 HydrophobicContact CB-CD1 4.47Å
24D97.2Very high88.8Confident70 Ų7074.2 Ų74.237%0.37436%0.362SS..  trans-66.7171.1175.274.237.4000111.6R26 E27 I28 R91D24-R26 PolarHBondContact O-N 3.01Å; D24-R26 WeakPolarHBondContact OD1-CA 3.38Å; D24-R26 VanDerWaalsContact OD1-CB 3.31Å; D24-R26 WeakPolarHBondContact OD1-CB 3.43Å; D24-R26 PolarHBondContact OD1-N 2.84Å; D24-E27 PolarHBondContact N-OE2 2.88Å; D24-E27 PolarHBondContact O-N 2.88Å; D24-E27 WeakPolarHBondContact OD1-CG 3.3Å; D24-E27 PolarHBondContact OD1-N 3.38Å; D24-I28 PolarHBondContact O-N 2.82Å; D24-R91 VanDerWaalsContact C-NH2 3.29Å; D24-R91 PolarHBondContact O-NH2 3.35Å
25N97.6Very high91.4Very high14 Ų1470 Ų708%0.07533%0.334CS..Hα-helixtrans-61-33.1-176.6-69.5-36.9000112.9E29 Q56 R91 P129 D133N25-E29 PolarHBondContact O-N 3.36Å; N25-E29 VanDerWaalsContact O-N 3.08Å; N25-Q56 VanDerWaalsContact CG-OE1 3.32Å; N25-Q56 PolarHBondContact ND2-NE2 2.85Å; N25-Q56 PolarHBondContact ND2-OE1 3.19Å; N25-R91 VanDerWaalsContact OD1-CZ 3.27Å; N25-R91 PolarHBondContact OD1-NH1 3.37Å; N25-R91 PolarHBondContact OD1-NH2 2.74Å; N25-P129 WeakPolarHBondContact ND2-CB 3.42Å; N25-P129 PolarHBondContact ND2-O 2.79Å; N25-P129 WeakPolarHBondContact OD1-CB 3.22Å; N25-D133 PolarHBondContact ND2-OD1 2.87Å; N25-D133 PolarHBondContact ND2-OD2 2.88Å
26R97.1Very high93.6Very high175 Ų17566.6 Ų66.666%0.6631%0.314SS*.Hα-helixtrans-73.2-41.8178-178.2-175.8178.5-179.41.9111.2D24 I28 E29 Q30D24-R26 PolarHBondContact O-N 3.01Å; D24-R26 WeakPolarHBondContact OD1-CA 3.38Å; D24-R26 VanDerWaalsContact OD1-CB 3.31Å; D24-R26 WeakPolarHBondContact OD1-CB 3.43Å; D24-R26 PolarHBondContact OD1-N 2.84Å; R26-I28 VanDerWaalsContact C-N 3.34Å; R26-E29 PolarHBondContact O-N 2.95Å; R26-Q30 WeakPolarHBondContact O-CB 3.27Å; R26-Q30 VanDerWaalsContact O-CG 3.27Å; R26-Q30 WeakPolarHBondContact O-CG 3.43Å; R26-Q30 PolarHBondContact O-N 3.1Å
27E97.8Very high95.8Very high53 Ų5362.7 Ų62.725%0.24830%0.304CS..Hα-helixtrans-64.2-39.2176.4-69.1-178.6127.400111.5R21 H23 D24 Q30 Y31R21-E27 IonicContact CZ-OE1 3.54Å; R21-E27 IonicContact CZ-OE2 2.82Å; R21-E27 VanDerWaalsContact NH1-CD 3.29Å; R21-E27 IonicContact NH1-OE1 3.68Å; R21-E27 PolarHBondContact NH1-OE1 3.09Å; R21-E27 IonicContact NH1-OE2 3.7Å; R21-E27 PolarHBondContact NH1-OE2 3.39Å; R21-E27 IonicContact NH2-OE1 2.71Å; R21-E27 PolarHBondContact NH2-OE1 3.3Å; R21-E27 IonicContact NH2-OE2 2.96Å; H23-E27 VanDerWaalsContact CA-OE2 3.29Å; H23-E27 WeakPolarHBondContact CA-OE2 3.48Å; H23-E27 HydrophobicContact CB-CB 4.06Å; D24-E27 PolarHBondContact N-OE2 2.88Å; D24-E27 PolarHBondContact O-N 2.88Å; D24-E27 WeakPolarHBondContact OD1-CG 3.3Å; D24-E27 PolarHBondContact OD1-N 3.38Å; E27-Q30 PolarHBondContact O-N 3.28Å; E27-Y31 VanDerWaalsContact O-CB 3.3Å; E27-Y31 WeakPolarHBondContact O-CB 3.19Å; E27-Y31 PolarHBondContact O-N 3.41Å
28I98.1Very high97.1Very high4 Ų458.8 Ų58.82%0.02129%0.286CS..Hα-helixtrans-61.9-48.7172.1-70.5-164.5000111H23 D24 R26 Q30 Y31 L32 R91 L95 P125H23-I28 HydrophobicContact CB-CG1 3.87Å; D24-I28 PolarHBondContact O-N 2.82Å; R26-I28 VanDerWaalsContact C-N 3.34Å; I28-Q30 VanDerWaalsContact C-N 3.33Å; I28-Q30 PolarHBondContact O-N 2.89Å; I28-Y31 PolarHBondContact O-N 2.9Å; I28-L32 HydrophobicContact CG2-CD1 3.73Å; I28-L32 HydrophobicContact CG2-CG 4.1Å; I28-L32 WeakPolarHBondContact O-CB 3.19Å; I28-L32 VanDerWaalsContact O-CG 3.28Å; I28-L32 WeakPolarHBondContact O-CG 3.33Å; I28-L32 PolarHBondContact O-N 2.94Å; I28-R91 HydrophobicContact CD1-CG 3.75Å; I28-L95 HydrophobicContact CD1-CD1 3.71Å; I28-L95 HydrophobicContact CD1-CD2 4.26Å; I28-L95 HydrophobicContact CD1-CG 4.35Å; I28-L95 HydrophobicContact CG1-CD1 3.81Å; I28-L95 HydrophobicContact CG1-CD2 4.35Å; I28-L95 HydrophobicContact CG2-CD2 4.16Å; I28-P125 HydrophobicContact CD1-CB 4.47Å
29E97.9Very high97.4Very high80 Ų8058.3 Ų58.337%0.37428%0.284SS..Hα-helixtrans-55.6-50177.1173172.4173.700111.1N25 R26 Y31 L32 V33 W59N25-E29 PolarHBondContact O-N 3.36Å; N25-E29 VanDerWaalsContact O-N 3.08Å; R26-E29 PolarHBondContact O-N 2.95Å; E29-Y31 VanDerWaalsContact C-N 3.34Å; E29-Y31 PolarHBondContact O-N 2.94Å; E29-L32 PolarHBondContact O-N 2.91Å; E29-V33 HydrophobicContact CG-CG2 4.33Å; E29-V33 WeakPolarHBondContact O-CB 3.25Å; E29-V33 VanDerWaalsContact O-CG2 3.27Å; E29-V33 WeakPolarHBondContact O-CG2 3.31Å; E29-V33 PolarHBondContact O-N 2.85Å; E29-W59 HydrophobicContact CG-CZ2 4.09Å; E29-W59 VanDerWaalsContact CG-NE1 3.35Å
30Q98Very high97.6Very high102 Ų10256.2 Ų56.248%0.47728%0.279SS..Hα-helixtrans-59.6-44.1179.2-73.2174.1-17.600112R26 E27 I28 Q34R26-Q30 WeakPolarHBondContact O-CB 3.27Å; R26-Q30 VanDerWaalsContact O-CG 3.27Å; R26-Q30 WeakPolarHBondContact O-CG 3.43Å; R26-Q30 PolarHBondContact O-N 3.1Å; E27-Q30 PolarHBondContact O-N 3.28Å; I28-Q30 VanDerWaalsContact C-N 3.33Å; I28-Q30 PolarHBondContact O-N 2.89Å; Q30-Q34 VanDerWaalsContact O-CB 3.3Å; Q30-Q34 WeakPolarHBondContact O-CB 3.44Å; Q30-Q34 PolarHBondContact O-N 3.49Å
31Y98.1Very high97.6Very high41 Ų4158.4 Ų58.416%0.16129%0.294CS..Hα-helixtrans-60.8-49176.2170.6-102.2000111.8L18 E27 I28 E29 V33 Q34 V35 L95 I98 A99L18-Y31 HydrophobicContact CB-CE2 4.32Å; L18-Y31 HydrophobicContact CD1-CD2 3.82Å; L18-Y31 HydrophobicContact CD1-CE2 3.81Å; L18-Y31 HydrophobicContact CD1-CG 4.29Å; L18-Y31 HydrophobicContact CD2-CE1 4.43Å; L18-Y31 HydrophobicContact CD2-CE2 4.37Å; L18-Y31 HydrophobicContact CG-CE2 4.39Å; E27-Y31 VanDerWaalsContact O-CB 3.3Å; E27-Y31 WeakPolarHBondContact O-CB 3.19Å; E27-Y31 PolarHBondContact O-N 3.41Å; I28-Y31 PolarHBondContact O-N 2.9Å; E29-Y31 VanDerWaalsContact C-N 3.34Å; E29-Y31 PolarHBondContact O-N 2.94Å; Y31-V33 PolarHBondContact O-N 3.28Å; Y31-Q34 PolarHBondContact O-N 2.9Å; Y31-V35 HydrophobicContact CD1-CG2 4.41Å; Y31-V35 HydrophobicContact CD2-CG2 3.96Å; Y31-V35 HydrophobicContact CE1-CG2 3.99Å; Y31-V35 HydrophobicContact CE2-CG2 3.48Å; Y31-V35 VanDerWaalsContact CE2-CG2 3.48Å; Y31-V35 HydrophobicContact CG-CG2 4.41Å; Y31-V35 WeakPolarHBondContact O-CB 3.34Å; Y31-V35 WeakPolarHBondContact O-CG2 3.34Å; Y31-V35 PolarHBondContact O-N 2.89Å; Y31-L95 HydrophobicContact CD1-CD2 3.89Å; Y31-L95 HydrophobicContact CE1-CB 4.37Å; Y31-L95 HydrophobicContact CE1-CD2 4.01Å; Y31-L95 PolarHBondContact OH-O 2.9Å; Y31-I98 HydrophobicContact CE1-CG2 4.18Å; Y31-A99 PolarHBondContact OH-N 2.85Å
32L98.6Very high97.7Very high0 Ų054.7 Ų54.70%028%0.28CS..Hα-helixtrans-65.5-40.3-178.5-66.8178.5000111.9I28 E29 S36 L45 W59 L61 L95 I98 P125I28-L32 HydrophobicContact CG2-CD1 3.73Å; I28-L32 HydrophobicContact CG2-CG 4.1Å; I28-L32 WeakPolarHBondContact O-CB 3.19Å; I28-L32 VanDerWaalsContact O-CG 3.28Å; I28-L32 WeakPolarHBondContact O-CG 3.33Å; I28-L32 PolarHBondContact O-N 2.94Å; E29-L32 PolarHBondContact O-N 2.91Å; L32-S36 VanDerWaalsContact O-CB 3.31Å; L32-S36 WeakPolarHBondContact O-CB 3.27Å; L32-S36 PolarHBondContact O-N 3.26Å; L32-L45 HydrophobicContact CB-CD1 3.83Å; L32-L45 HydrophobicContact CB-CD2 4.08Å; L32-L45 HydrophobicContact CD1-CD1 4.19Å; L32-W59 HydrophobicContact CD1-CB 3.6Å; L32-W59 HydrophobicContact CD1-CG 4.32Å; L32-L61 HydrophobicContact CD2-CB 4.23Å; L32-L61 HydrophobicContact CD2-CD2 4.3Å; L32-L95 HydrophobicContact CD2-CD2 4.33Å; L32-I98 HydrophobicContact CD2-CD1 3.65Å; L32-P125 HydrophobicContact CD1-CG 4.33Å
33V98.5Very high97.8Very high71 Ų7152.8 Ų52.843%0.4327%0.273SS..Hα-helixtrans-60.8-47.2174.6168.90000110.2E29 Y31 S36 A37 L45E29-V33 HydrophobicContact CG-CG2 4.33Å; E29-V33 WeakPolarHBondContact O-CB 3.25Å; E29-V33 VanDerWaalsContact O-CG2 3.27Å; E29-V33 WeakPolarHBondContact O-CG2 3.31Å; E29-V33 PolarHBondContact O-N 2.85Å; Y31-V33 PolarHBondContact O-N 3.28Å; V33-S36 PolarHBondContact O-N 2.97Å; V33-A37 WeakPolarHBondContact O-CB 3.46Å; V33-A37 PolarHBondContact O-N 3.46Å; V33-L45 HydrophobicContact CB-CD2 4.29Å; V33-L45 HydrophobicContact CG2-CD2 3.59Å
34Q97.9Very high97.9Very high103 Ų10354.2 Ų54.248%0.48128%0.279SS..Hα-helixtrans-64-48.8179.8-173.562.244.400111.7Q30 Y31 S36 A37 D38Q30-Q34 VanDerWaalsContact O-CB 3.3Å; Q30-Q34 WeakPolarHBondContact O-CB 3.44Å; Q30-Q34 PolarHBondContact O-N 3.49Å; Y31-Q34 PolarHBondContact O-N 2.9Å; Q34-S36 VanDerWaalsContact C-N 3.27Å; Q34-S36 PolarHBondContact O-N 3.27Å; Q34-A37 PolarHBondContact O-N 2.92Å; Q34-A37 VanDerWaalsContact O-N 3.13Å; Q34-D38 PolarHBondContact NE2-OD1 3.24Å; Q34-D38 PolarHBondContact NE2-OD2 3.16Å; Q34-D38 WeakPolarHBondContact O-CB 3.34Å; Q34-D38 VanDerWaalsContact O-CG 3.31Å; Q34-D38 PolarHBondContact O-N 3.42Å
35V97.9Very high98Very high14 Ų1452.3 Ų52.39%0.08527%0.269CS..Hα-helixtrans-58.4-41.6177.2168.90000111.2Y31 D38 N39 T43 L61 I98 V102Y31-V35 HydrophobicContact CD1-CG2 4.41Å; Y31-V35 HydrophobicContact CD2-CG2 3.96Å; Y31-V35 HydrophobicContact CE1-CG2 3.99Å; Y31-V35 HydrophobicContact CE2-CG2 3.48Å; Y31-V35 VanDerWaalsContact CE2-CG2 3.48Å; Y31-V35 HydrophobicContact CG-CG2 4.41Å; Y31-V35 WeakPolarHBondContact O-CB 3.34Å; Y31-V35 WeakPolarHBondContact O-CG2 3.34Å; Y31-V35 PolarHBondContact O-N 2.89Å; V35-D38 PolarHBondContact O-N 3.04Å; V35-N39 WeakPolarHBondContact O-CB 3.46Å; V35-N39 PolarHBondContact O-N 2.99Å; V35-N39 VanDerWaalsContact O-N 3.11Å; V35-N39 PolarHBondContact O-ND2 3.41Å; V35-T43 HydrophobicContact CG1-CG2 4.45Å; V35-L61 HydrophobicContact CG1-CD2 3.97Å; V35-I98 HydrophobicContact CG1-CG2 3.93Å; V35-V102 HydrophobicContact CG1-CG2 4.04Å
36S98.1Very high98Very high25 Ų2553.7 Ų53.718%0.17527%0.273CS..Hα-helixtrans-66.8-36.2177.9-172.20000113L32 V33 Q34 T43 L45L32-S36 VanDerWaalsContact O-CB 3.31Å; L32-S36 WeakPolarHBondContact O-CB 3.27Å; L32-S36 PolarHBondContact O-N 3.26Å; V33-S36 PolarHBondContact O-N 2.97Å; Q34-S36 VanDerWaalsContact C-N 3.27Å; Q34-S36 PolarHBondContact O-N 3.27Å; S36-T43 WeakPolarHBondContact CA-OG1 3.35Å; S36-T43 PolarHBondContact O-OG1 2.9Å; S36-L45 PolarHBondContact OG-N 2.87Å
37A97.9Very high98.1Very high67 Ų6747.3 Ų47.355%0.55426%0.255SS*.Hα-helixtrans-72-37.217800000111.9V33 Q34 P40V33-A37 WeakPolarHBondContact O-CB 3.46Å; V33-A37 PolarHBondContact O-N 3.46Å; Q34-A37 PolarHBondContact O-N 2.92Å; Q34-A37 VanDerWaalsContact O-N 3.13Å; A37-P40 WeakPolarHBondContact O-CD 3.47Å
38D97.4Very high98.1Very high84 Ų8446.1 Ų46.145%0.44925%0.251SS..Hα-helixtrans-82.1-12.2-178.2-67.1-19.3000113.8Q34 V35 R106Q34-D38 PolarHBondContact NE2-OD1 3.24Å; Q34-D38 PolarHBondContact NE2-OD2 3.16Å; Q34-D38 WeakPolarHBondContact O-CB 3.34Å; Q34-D38 VanDerWaalsContact O-CG 3.31Å; Q34-D38 PolarHBondContact O-N 3.42Å; V35-D38 PolarHBondContact O-N 3.04Å; D38-R106 PolarHBondContact O-NH2 3.11Å
39N97.5Very high98.1Very high12 Ų1247 Ų476%0.06426%0.261CS..  trans-136.950.4-177.1-55-82.1000112.9V35 D41 I42 T43 V102 R106V35-N39 WeakPolarHBondContact O-CB 3.46Å; V35-N39 PolarHBondContact O-N 2.99Å; V35-N39 VanDerWaalsContact O-N 3.11Å; V35-N39 PolarHBondContact O-ND2 3.41Å; N39-D41 PolarHBondContact O-N 3.01Å; N39-D41 VanDerWaalsContact O-N 3.11Å; N39-I42 HydrophobicContact CB-CD1 4.32Å; N39-I42 HydrophobicContact CB-CG1 3.92Å; N39-I42 PolarHBondContact O-N 2.95Å; N39-I42 VanDerWaalsContact O-N 3.16Å; N39-T43 HydrophobicContact CB-CG2 4.04Å; N39-T43 PolarHBondContact O-N 3.33Å; N39-T43 PolarHBondContact O-OG1 3.29Å; N39-V102 WeakPolarHBondContact OD1-CG1 3.37Å; N39-R106 VanDerWaalsContact CG-NH2 3.27Å; N39-R106 PolarHBondContact ND2-NH2 2.88Å; N39-R106 PolarHBondContact OD1-NE 3.3Å; N39-R106 PolarHBondContact OD1-NH2 2.86Å
40P97.4Very high98.1Very high63 Ų6348.7 Ų48.741%0.40927%0.267SS..THydrogen-bonded Turntrans-64.8-21.7-170.728.8-36.5000113.6A37 I42A37-P40 WeakPolarHBondContact O-CD 3.47Å; P40-I42 VanDerWaalsContact C-N 3.32Å
41D96.8Very high98.1Very high115 Ų11544.1 Ų44.162%0.61525%0.246SC*.THydrogen-bonded Turntrans-71.2-28.4-179.9-61.2-33.5000112.8N39N39-D41 PolarHBondContact O-N 3.01Å; N39-D41 VanDerWaalsContact O-N 3.11Å
42I98.3Very high97.8Very high1 Ų144.6 Ų44.61%0.00525%0.253CS..THydrogen-bonded Turntrans-123.3-2-174.556.8149.8000114.1N39 P40 L63 G64 L65 V102 Y105 L116N39-I42 HydrophobicContact CB-CD1 4.32Å; N39-I42 HydrophobicContact CB-CG1 3.92Å; N39-I42 PolarHBondContact O-N 2.95Å; N39-I42 VanDerWaalsContact O-N 3.16Å; P40-I42 VanDerWaalsContact C-N 3.32Å; I42-L63 CarbonylContact O-C 3.57Å; I42-L63 WeakPolarHBondContact O-CA 3.46Å; I42-G64 CarbonylContact C-O 3.5Å; I42-G64 WeakPolarHBondContact CA-O 3.37Å; I42-G64 PolarHBondContact O-N 3.38Å; I42-L65 HydrophobicContact CG2-CD2 3.96Å; I42-V102 HydrophobicContact CD1-CG2 4.23Å; I42-Y105 HydrophobicContact CD1-CD1 3.57Å; I42-Y105 HydrophobicContact CD1-CD2 4.36Å; I42-Y105 HydrophobicContact CD1-CE1 4.24Å; I42-Y105 HydrophobicContact CD1-CG 3.64Å; I42-Y105 HydrophobicContact CG1-CD1 3.99Å; I42-Y105 HydrophobicContact CG1-CE1 4.16Å; I42-Y105 HydrophobicContact CG1-CG 4.35Å; I42-Y105 HydrophobicContact CG2-CD1 4.04Å; I42-Y105 HydrophobicContact CG2-CD2 3.72Å; I42-Y105 HydrophobicContact CG2-CE1 3.71Å; I42-Y105 HydrophobicContact CG2-CE2 3.39Å; I42-Y105 HydrophobicContact CG2-CG 4.05Å; I42-L116 HydrophobicContact CD1-CD1 4.24Å
43T98.7Very high97.3Very high0 Ų048.2 Ų48.20%027%0.269CS..EExtended strand (participates in β ladder)trans-130.9152.6-177.762.80000113.4V35 S36 N39 L61 A62 L63 P67 V102V35-T43 HydrophobicContact CG1-CG2 4.45Å; S36-T43 WeakPolarHBondContact CA-OG1 3.35Å; S36-T43 PolarHBondContact O-OG1 2.9Å; N39-T43 HydrophobicContact CB-CG2 4.04Å; N39-T43 PolarHBondContact O-N 3.33Å; N39-T43 PolarHBondContact O-OG1 3.29Å; T43-L61 HydrophobicContact CG2-CD2 4.33Å; T43-A62 CarbonylContact C-O 3.29Å; T43-A62 VanDerWaalsContact CA-O 3.25Å; T43-A62 WeakPolarHBondContact CA-O 3.32Å; T43-L63 HydrophobicContact CG2-CD2 4.14Å; T43-L63 HydrophobicContact CG2-CG 4.25Å; T43-P67 WeakPolarHBondContact O-CG 3.46Å; T43-V102 HydrophobicContact CG2-CG2 4.42Å
44H98.7Very high96.7Very high45 Ų4550 Ų5021%0.20829%0.291CS..EExtended strand (participates in β ladder)trans-147.9110.4172175.9-98.7000109.6Y46 A62 P67 R68H44-Y46 AromaticContact CE1-CD1 3.86Å; H44-Y46 AromaticContact ND1-CD1 3.43Å; H44-Y46 WeakPolarHBondContact ND1-CD1 3.19Å; H44-A62 HydrophobicContact CB-CB 4.4Å; H44-A62 PolarHBondContact N-O 2.89Å; H44-A62 PolarHBondContact O-N 2.98Å; H44-P67 HydrophobicContact CB-CB 3.89Å; H44-P67 HydrophobicContact CB-CG 4.44Å; H44-R68 HydrophobicContact CB-CG 4.07Å
45L98.8Very high96.5Very high30 Ų3046.1 Ų46.116%0.15728%0.279CS..EExtended strand (participates in β ladder)trans-84.3134.2173.2-177.964.1000110.9L32 V33 S36 W59 V60 L61L32-L45 HydrophobicContact CB-CD1 3.83Å; L32-L45 HydrophobicContact CB-CD2 4.08Å; L32-L45 HydrophobicContact CD1-CD1 4.19Å; V33-L45 HydrophobicContact CB-CD2 4.29Å; V33-L45 HydrophobicContact CG2-CD2 3.59Å; S36-L45 PolarHBondContact OG-N 2.87Å; L45-W59 HydrophobicContact CD1-CB 4.13Å; L45-W59 HydrophobicContact CD1-CD2 4.25Å; L45-W59 HydrophobicContact CD1-CE3 3.76Å; L45-W59 HydrophobicContact CD1-CG 4.44Å; L45-W59 HydrophobicContact CD2-CE3 4.11Å; L45-W59 HydrophobicContact CD2-CZ3 4.25Å; L45-W59 HydrophobicContact CG-CE3 3.78Å; L45-W59 HydrophobicContact CG-CZ3 4.08Å; L45-V60 WeakPolarHBondContact CD1-O 3.5Å; L45-L61 HydrophobicContact CB-CD1 3.94Å; L45-L61 HydrophobicContact CD1-CD1 4.27Å
46Y98.8Very high96.4Very high43 Ų4347.5 Ų47.517%0.16928%0.284CS..EExtended strand (participates in β ladder)trans-151.1164.5172.564.3-77.7000110.4H44 I48 V60 A62 H122 W185H44-Y46 AromaticContact CE1-CD1 3.86Å; H44-Y46 AromaticContact ND1-CD1 3.43Å; H44-Y46 WeakPolarHBondContact ND1-CD1 3.19Å; Y46-I48 HydrophobicContact CD2-CG2 4.09Å; Y46-I48 HydrophobicContact CE2-CG2 3.55Å; Y46-V60 HydrophobicContact CD1-CB 4.37Å; Y46-V60 WeakPolarHBondContact CD1-O 3.36Å; Y46-V60 HydrophobicContact CD2-CB 4.48Å; Y46-V60 HydrophobicContact CE1-CB 3.82Å; Y46-V60 HydrophobicContact CE1-CG1 3.73Å; Y46-V60 HydrophobicContact CE2-CB 3.95Å; Y46-V60 HydrophobicContact CE2-CG1 4.36Å; Y46-V60 HydrophobicContact CE2-CG2 4.36Å; Y46-V60 PolarHBondContact N-O 3.01Å; Y46-V60 PolarHBondContact O-N 3.28Å; Y46-V60 WeakPolarHBondContact OH-CG1 3.25Å; Y46-A62 HydrophobicContact CE1-CB 4.05Å; Y46-H122 AromaticContact CE1-ND1 3.93Å; Y46-H122 AromaticContact CZ-ND1 3.74Å; Y46-H122 PolarHBondContact OH-CE1 3.42Å; Y46-H122 PolarHBondContact OH-ND1 3.11Å; Y46-W185 AromaticContact CZ-NE1 3.97Å; Y46-W185 PolarHBondContact OH-NE1 3.23Å
47S98.5Very high96.4Very high40 Ų4049.1 Ų49.128%0.2829%0.289SS..EExtended strand (participates in β ladder)trans-108.6138.2175.21760000110G49 Q57 L58S47-G49 PolarHBondContact OG-N 3.24Å; S47-G49 PolarHBondContact OG-O 3.01Å; S47-Q57 VanDerWaalsContact CB-OE1 3.24Å; S47-Q57 PolarHBondContact OG-OE1 2.9Å; S47-L58 WeakPolarHBondContact CA-O 3.42Å
48I98.6Very high96.4Very high29 Ų2945.9 Ų45.915%0.14926%0.263CS..EExtended strand (participates in β ladder)trans-93.8-6176.759.9166.1000113.1Y46 L58 V60 L124 A181 V182 W185Y46-I48 HydrophobicContact CD2-CG2 4.09Å; Y46-I48 HydrophobicContact CE2-CG2 3.55Å; I48-L58 HydrophobicContact CD1-CB 4.23Å; I48-L58 HydrophobicContact CD1-CD2 4.36Å; I48-L58 HydrophobicContact CG1-CB 3.59Å; I48-L58 HydrophobicContact CG1-CD2 4.38Å; I48-L58 WeakPolarHBondContact CG1-O 3.28Å; I48-L58 PolarHBondContact N-O 2.89Å; I48-V60 HydrophobicContact CD1-CG2 4.34Å; I48-V60 HydrophobicContact CG1-CG2 4.26Å; I48-V60 HydrophobicContact CG2-CG2 3.67Å; I48-L124 HydrophobicContact CD1-CD2 3.85Å; I48-A181 HydrophobicContact CD1-CB 4.41Å; I48-A181 HydrophobicContact CG1-CB 4.29Å; I48-A181 WeakPolarHBondContact O-CB 3.42Å; I48-V182 HydrophobicContact CD1-CG2 4.01Å; I48-W185 HydrophobicContact CB-CB 4.03Å; I48-W185 HydrophobicContact CB-CG 4.26Å; I48-W185 HydrophobicContact CD1-CB 4.15Å; I48-W185 HydrophobicContact CD1-CD2 4.17Å; I48-W185 HydrophobicContact CD1-CE3 3.87Å; I48-W185 HydrophobicContact CD1-CG 4.31Å; I48-W185 HydrophobicContact CG2-CB 3.79Å; I48-W185 HydrophobicContact CG2-CD2 3.97Å; I48-W185 HydrophobicContact CG2-CG 3.5Å; I48-W185 VanDerWaalsContact CG2-CG 3.5Å
49G98.1Very high96.5Very high23 Ų2344.1 Ų44.124%0.23725%0.25CC..EExtended strand (participates in β ladder)trans158.2-168.4-175.600000111.5S47 L58S47-G49 PolarHBondContact OG-N 3.24Å; S47-G49 PolarHBondContact OG-O 3.01Å; G49-L58 PolarHBondContact O-N 2.91Å
50K98.3Very high96.6Very high115 Ų11543.6 Ų43.650%0.525%0.247SC..EExtended strand (participates in β ladder)trans-128.5146.9179.7-64.2-178.9178.6-170.30110.5G55 Q56 Q57 A177K50-G55 WeakPolarHBondContact CD-O 3.22Å; K50-Q56 CarbonylContact C-O 3.54Å; K50-Q56 WeakPolarHBondContact CA-O 3.3Å; K50-Q57 VanDerWaalsContact CE-NE2 3.28Å; K50-A177 WeakPolarHBondContact O-CB 3.45Å
51S96.9Very high96.6Very high6 Ų640.6 Ų40.64%0.04223%0.227CC..  trans-69.6169.8169.372.40000111.2K53 G55 Q56 L58 D130 E178S51-K53 PolarHBondContact OG-O 3.34Å; S51-G55 WeakPolarHBondContact O-CA 3.24Å; S51-Q56 PolarHBondContact N-O 2.69Å; S51-Q56 VanDerWaalsContact OG-CB 3.31Å; S51-Q56 WeakPolarHBondContact OG-CB 3.46Å; S51-Q56 PolarHBondContact OG-N 2.82Å; S51-Q56 VanDerWaalsContact OG-N 3.13Å; S51-L58 VanDerWaalsContact N-CD1 3.29Å; S51-D130 VanDerWaalsContact CB-CG 3.46Å; S51-D130 VanDerWaalsContact CB-OD1 3.3Å; S51-D130 WeakPolarHBondContact CB-OD1 3.24Å; S51-D130 WeakPolarHBondContact CB-OD2 3.3Å; S51-D130 VanDerWaalsContact OG-CG 3.23Å; S51-D130 PolarHBondContact OG-OD1 3.35Å; S51-D130 PolarHBondContact OG-OD2 2.76Å; S51-E178 VanDerWaalsContact CA-OE1 3.27Å; S51-E178 WeakPolarHBondContact CA-OE1 3.48Å; S51-E178 WeakPolarHBondContact CB-OE1 3.19Å
52V93.3Very high96.7Very high50 Ų5035.1 Ų35.130%0.30320%0.198SC..SBendtrans-71.4-46.8-177.31790000111.9D130 H148 A177 E178V52-D130 PolarHBondContact N-OD2 3.18Å; V52-D130 VanDerWaalsContact N-OD2 3.09Å; V52-H148 HydrophobicContact CB-CB 4.1Å; V52-H148 HydrophobicContact CG1-CB 4.33Å; V52-A177 HydrophobicContact CG2-CB 4.03Å; V52-E178 PolarHBondContact N-OE1 3.39Å; V52-E178 VanDerWaalsContact N-OE1 3.13Å
53K87.7Confident96.8Very high77 Ų7735 Ų3534%0.33520%0.198SC..SBendtrans-83.7120.2-174.4-163.2-174.4-170.6170.70110.4S51 G55 D130 E134 H148S51-K53 PolarHBondContact OG-O 3.34Å; K53-G55 PolarHBondContact O-N 3.28Å; K53-D130 HydrophobicContact CB-CB 4.05Å; K53-D130 VanDerWaalsContact CB-OD2 3.29Å; K53-D130 WeakPolarHBondContact CB-OD2 3.38Å; K53-D130 PolarHBondContact N-OD2 3.37Å; K53-E134 IonicContact NZ-OE1 3.29Å; K53-E134 PolarHBondContact NZ-OE1 3.06Å; K53-H148 HydrophobicContact CB-CB 3.96Å; K53-H148 WeakPolarHBondContact CD-ND1 3.49Å
54A85.3Confident96.7Very high107 Ų10735.1 Ų35.188%0.88420%0.199SC*.THydrogen-bonded Turntrans57.21.3-179.900000115.9
55G93Very high96.6Very high23 Ų2336.6 Ų36.624%0.23721%0.207CC..THydrogen-bonded Turntrans70.642.4176.700000113.9K50 S51 K53K50-G55 WeakPolarHBondContact CD-O 3.22Å; S51-G55 WeakPolarHBondContact O-CA 3.24Å; K53-G55 PolarHBondContact O-N 3.28Å
56Q96.4Very high96.4Very high42 Ų4241.3 Ų41.320%0.19622%0.223CC..  trans-62.7138.2178.5-51.5-16974.200110.3N25 K50 S51 P129 D130 D133N25-Q56 VanDerWaalsContact CG-OE1 3.32Å; N25-Q56 PolarHBondContact ND2-NE2 2.85Å; N25-Q56 PolarHBondContact ND2-OE1 3.19Å; K50-Q56 CarbonylContact C-O 3.54Å; K50-Q56 WeakPolarHBondContact CA-O 3.3Å; S51-Q56 PolarHBondContact N-O 2.69Å; S51-Q56 VanDerWaalsContact OG-CB 3.31Å; S51-Q56 WeakPolarHBondContact OG-CB 3.46Å; S51-Q56 PolarHBondContact OG-N 2.82Å; S51-Q56 VanDerWaalsContact OG-N 3.13Å; Q56-P129 HydrophobicContact CB-CB 4.29Å; Q56-P129 HydrophobicContact CB-CG 3.99Å; Q56-D130 PolarHBondContact NE2-OD1 2.88Å; Q56-D133 PolarHBondContact NE2-OD2 3.49Å; Q56-D133 PolarHBondContact OE1-OD2 3.44Å
57Q98.1Very high96.2Very high59 Ų5939.7 Ų39.728%0.27622%0.218SC..EExtended strand (participates in β ladder)trans-74.8135.2-175.4-60.5-74.6-7.600110.7S47 K50 W59S47-Q57 VanDerWaalsContact CB-OE1 3.24Å; S47-Q57 PolarHBondContact OG-OE1 2.9Å; K50-Q57 VanDerWaalsContact CE-NE2 3.28Å; Q57-W59 VanDerWaalsContact C-N 3.34Å; Q57-W59 HydrophobicContact CB-CD2 3.83Å; Q57-W59 HydrophobicContact CB-CG 4.16Å; Q57-W59 HydrophobicContact CB-CH2 4.39Å; Q57-W59 HydrophobicContact CB-CZ2 3.71Å; Q57-W59 HydrophobicContact CG-CH2 4.23Å; Q57-W59 HydrophobicContact CG-CZ2 3.63Å; Q57-W59 PolarHBondContact O-N 3.01Å; Q57-W59 VanDerWaalsContact O-N 3.12Å
58L98.8Very high96.2Very high0 Ų045.8 Ų45.80%024%0.235CC..EExtended strand (participates in β ladder)trans-84.885.2169.9-82.464.2000107.9S47 I48 G49 S51 L124 P129 E178 A181S47-L58 WeakPolarHBondContact CA-O 3.42Å; I48-L58 HydrophobicContact CD1-CB 4.23Å; I48-L58 HydrophobicContact CD1-CD2 4.36Å; I48-L58 HydrophobicContact CG1-CB 3.59Å; I48-L58 HydrophobicContact CG1-CD2 4.38Å; I48-L58 WeakPolarHBondContact CG1-O 3.28Å; I48-L58 PolarHBondContact N-O 2.89Å; G49-L58 PolarHBondContact O-N 2.91Å; S51-L58 VanDerWaalsContact N-CD1 3.29Å; L58-L124 HydrophobicContact CB-CD1 4.35Å; L58-P129 HydrophobicContact CD1-CG 4.38Å; L58-E178 HydrophobicContact CD2-CB 4.12Å; L58-E178 HydrophobicContact CD2-CG 4.26Å; L58-A181 HydrophobicContact CD2-CB 3.95Å
59W98.8Very high96Very high47 Ų4753 Ų5318%0.17826%0.26CS..EExtended strand (participates in β ladder)trans-73.5130.7-175.5-69.5119.4000112.7E29 L32 L45 Q57 L124 P125E29-W59 HydrophobicContact CG-CZ2 4.09Å; E29-W59 VanDerWaalsContact CG-NE1 3.35Å; L32-W59 HydrophobicContact CD1-CB 3.6Å; L32-W59 HydrophobicContact CD1-CG 4.32Å; L45-W59 HydrophobicContact CD1-CB 4.13Å; L45-W59 HydrophobicContact CD1-CD2 4.25Å; L45-W59 HydrophobicContact CD1-CE3 3.76Å; L45-W59 HydrophobicContact CD1-CG 4.44Å; L45-W59 HydrophobicContact CD2-CE3 4.11Å; L45-W59 HydrophobicContact CD2-CZ3 4.25Å; L45-W59 HydrophobicContact CG-CE3 3.78Å; L45-W59 HydrophobicContact CG-CZ3 4.08Å; Q57-W59 VanDerWaalsContact C-N 3.34Å; Q57-W59 HydrophobicContact CB-CD2 3.83Å; Q57-W59 HydrophobicContact CB-CG 4.16Å; Q57-W59 HydrophobicContact CB-CH2 4.39Å; Q57-W59 HydrophobicContact CB-CZ2 3.71Å; Q57-W59 HydrophobicContact CG-CH2 4.23Å; Q57-W59 HydrophobicContact CG-CZ2 3.63Å; Q57-W59 PolarHBondContact O-N 3.01Å; Q57-W59 VanDerWaalsContact O-N 3.12Å; W59-L124 WeakPolarHBondContact O-CD1 3.42Å; W59-P125 WeakPolarHBondContact O-CD 3.48Å
60V98.9Very high95.9Very high0 Ų053.6 Ų53.60%026%0.257CS..EExtended strand (participates in β ladder)trans-121128.9171.2-1760000109.6L45 Y46 I48 H122 I123 L124 W185L45-V60 WeakPolarHBondContact CD1-O 3.5Å; Y46-V60 HydrophobicContact CD1-CB 4.37Å; Y46-V60 WeakPolarHBondContact CD1-O 3.36Å; Y46-V60 HydrophobicContact CD2-CB 4.48Å; Y46-V60 HydrophobicContact CE1-CB 3.82Å; Y46-V60 HydrophobicContact CE1-CG1 3.73Å; Y46-V60 HydrophobicContact CE2-CB 3.95Å; Y46-V60 HydrophobicContact CE2-CG1 4.36Å; Y46-V60 HydrophobicContact CE2-CG2 4.36Å; Y46-V60 PolarHBondContact N-O 3.01Å; Y46-V60 PolarHBondContact O-N 3.28Å; Y46-V60 WeakPolarHBondContact OH-CG1 3.25Å; I48-V60 HydrophobicContact CD1-CG2 4.34Å; I48-V60 HydrophobicContact CG1-CG2 4.26Å; I48-V60 HydrophobicContact CG2-CG2 3.67Å; V60-H122 HydrophobicContact CG1-CB 3.91Å; V60-I123 WeakPolarHBondContact CA-O 3.28Å; V60-L124 HydrophobicContact CG2-CB 4.08Å; V60-L124 HydrophobicContact CG2-CD1 4.03Å; V60-L124 HydrophobicContact CG2-CG 4.49Å; V60-W185 HydrophobicContact CG1-CH2 4.48Å; V60-W185 HydrophobicContact CG1-CZ2 3.97Å; V60-W185 HydrophobicContact CG2-CH2 4.5Å; V60-W185 HydrophobicContact CG2-CZ2 4.34Å
61L98.9Very high95.8Very high0 Ų048.3 Ų48.30%024%0.235CC..EExtended strand (participates in β ladder)trans-100.9113169.2-166.273.8000108.7L32 V35 T43 L45 L63 I98 I123L32-L61 HydrophobicContact CD2-CB 4.23Å; L32-L61 HydrophobicContact CD2-CD2 4.3Å; V35-L61 HydrophobicContact CG1-CD2 3.97Å; T43-L61 HydrophobicContact CG2-CD2 4.33Å; L45-L61 HydrophobicContact CB-CD1 3.94Å; L45-L61 HydrophobicContact CD1-CD1 4.27Å; L61-L63 HydrophobicContact CD2-CD1 4.26Å; L61-L63 HydrophobicContact CD2-CD2 4.41Å; L61-L63 HydrophobicContact CD2-CG 4.32Å; L61-L63 HydrophobicContact CG-CD1 4.34Å; L61-L63 HydrophobicContact CG-CG 4.46Å; L61-L63 WeakPolarHBondContact O-CD1 3.31Å; L61-I98 HydrophobicContact CB-CD1 4.24Å; L61-I98 HydrophobicContact CD2-CB 4.42Å; L61-I98 HydrophobicContact CD2-CD1 3.89Å; L61-I98 HydrophobicContact CD2-CG1 4.04Å; L61-I98 HydrophobicContact CD2-CG2 3.49Å; L61-I98 VanDerWaalsContact CD2-CG2 3.49Å; L61-I123 PolarHBondContact N-O 3Å; L61-I123 PolarHBondContact O-N 3.43Å
62A98.8Very high95.8Very high0 Ų051.2 Ų51.20%025%0.252CS..EExtended strand (participates in β ladder)trans-83.4134.5167.600000109.7T43 H44 Y46 I121T43-A62 CarbonylContact C-O 3.29Å; T43-A62 VanDerWaalsContact CA-O 3.25Å; T43-A62 WeakPolarHBondContact CA-O 3.32Å; H44-A62 HydrophobicContact CB-CB 4.4Å; H44-A62 PolarHBondContact N-O 2.89Å; H44-A62 PolarHBondContact O-N 2.98Å; Y46-A62 HydrophobicContact CE1-CB 4.05Å; A62-I121 CarbonylContact C-O 3.52Å; A62-I121 VanDerWaalsContact CA-O 3.3Å; A62-I121 WeakPolarHBondContact CA-O 3.3Å
63L98.8Very high96Very high0 Ų050 Ų500%025%0.249CC..EExtended strand (participates in β ladder)trans-123137.5176.6-54.897.6000111.2I42 T43 L61 I98 L101 V102 L116 R120 I121 I123I42-L63 CarbonylContact O-C 3.57Å; I42-L63 WeakPolarHBondContact O-CA 3.46Å; T43-L63 HydrophobicContact CG2-CD2 4.14Å; T43-L63 HydrophobicContact CG2-CG 4.25Å; L61-L63 HydrophobicContact CD2-CD1 4.26Å; L61-L63 HydrophobicContact CD2-CD2 4.41Å; L61-L63 HydrophobicContact CD2-CG 4.32Å; L61-L63 HydrophobicContact CG-CD1 4.34Å; L61-L63 HydrophobicContact CG-CG 4.46Å; L61-L63 WeakPolarHBondContact O-CD1 3.31Å; L63-I98 HydrophobicContact CD1-CG1 4.43Å; L63-L101 HydrophobicContact CD2-CB 4.15Å; L63-L101 HydrophobicContact CD2-CD1 4.27Å; L63-V102 HydrophobicContact CD2-CG2 4.19Å; L63-L116 HydrophobicContact CB-CD2 3.82Å; L63-R120 WeakPolarHBondContact O-CA 3.4Å; L63-I121 HydrophobicContact CB-CB 4.49Å; L63-I121 PolarHBondContact N-O 2.83Å; L63-I121 PolarHBondContact O-N 2.73Å; L63-I123 HydrophobicContact CD1-CD1 3.84Å; L63-I123 HydrophobicContact CD1-CG1 4.14Å
64G98.1Very high96.5Very high2 Ų247.2 Ų47.22%0.02124%0.238CC..SBendtrans153.9168.6176.600000111.3I42 R66 P67 L116I42-G64 CarbonylContact C-O 3.5Å; I42-G64 WeakPolarHBondContact CA-O 3.37Å; I42-G64 PolarHBondContact O-N 3.38Å; G64-R66 PolarHBondContact O-N 3.32Å; G64-R66 VanDerWaalsContact O-N 3.1Å; G64-P67 WeakPolarHBondContact O-CD 3.1Å; G64-L116 CarbonylContact C-O 3.56Å; G64-L116 VanDerWaalsContact CA-O 3.24Å; G64-L116 WeakPolarHBondContact CA-O 3.25Å
65L95.2Very high97.1Very high75 Ų7542.1 Ų42.139%0.39320%0.196SC..SBendtrans-67.8-11.3-177.6-63.2-169.2000114.4I42 Y105 L116 N117I42-L65 HydrophobicContact CG2-CD2 3.96Å; L65-Y105 HydrophobicContact CD2-CE2 3.98Å; L65-L116 PolarHBondContact N-O 2.98Å; L65-N117 HydrophobicContact CD1-CB 3.69Å; L65-N117 WeakPolarHBondContact CD1-OD1 3.33Å; L65-N117 HydrophobicContact CG-CB 4.21Å
66R94.6Very high97.4Very high129 Ų12941 Ų4149%0.48719%0.185SC..SBendtrans-130.267171.6-72.4-175.8-88.5171.6-4.7109.2G64 R68G64-R66 PolarHBondContact O-N 3.32Å; G64-R66 VanDerWaalsContact O-N 3.1Å; R66-R68 VanDerWaalsContact C-N 3.31Å; R66-R68 PolarHBondContact O-N 3.08Å
67P96.3Very high97.5Very high10 Ų1039 Ų397%0.06518%0.176CC..THydrogen-bonded Turntrans-72.7-25.5-162.929.8-34.3000113T43 H44 G64 R120T43-P67 WeakPolarHBondContact O-CG 3.46Å; H44-P67 HydrophobicContact CB-CB 3.89Å; H44-P67 HydrophobicContact CB-CG 4.44Å; G64-P67 WeakPolarHBondContact O-CD 3.1Å; P67-R120 PolarHBondContact O-NE 3.16Å; P67-R120 PolarHBondContact O-NH2 3.28Å
68R97.1Very high97.6Very high167 Ų16736.2 Ų36.263%0.6316%0.163SC*.THydrogen-bonded Turntrans-83.7-18.1-174.5-53.5-161.6172.1-139.5-0.8115.2H44 R66H44-R68 HydrophobicContact CB-CG 4.07Å; R66-R68 VanDerWaalsContact C-N 3.31Å; R66-R68 PolarHBondContact O-N 3.08Å
69R94.4Very high97.6Very high182 Ų18236.2 Ų36.269%0.68716%0.163SC*.SBendtrans-151.1143.8-171.961.8-176.7174.6-162.9-1.9111.1
70H96.1Very high97.6Very high35 Ų3534 Ų3416%0.16216%0.155CC..  trans-52.7148.8169.6179.763.1000111.9V74 E76 H356 E358H70-V74 PolarHBondContact CE1-O 3.28Å; H70-E76 IonicContact CE1-OE1 3.05Å; H70-E76 IonicContact CG-OE1 3.78Å; H70-E76 IonicContact ND1-OE1 2.95Å; H70-E76 PolarHBondContact ND1-OE1 2.99Å; H70-H356 AromaticContact CD2-CD2 3.72Å; H70-E358 IonicContact CD2-OE2 3.42Å; H70-E358 IonicContact CE1-OE1 3.68Å; H70-E358 IonicContact CE1-OE2 2.71Å; H70-E358 IonicContact NE2-OE1 2.94Å; H70-E358 IonicContact NE2-OE2 3.74Å; H70-E358 PolarHBondContact NE2-OE2 3.17Å
71A96.6Very high97.6Very high4 Ų434.1 Ų34.13%0.03316%0.155CC..  trans-134114.6-176.100000109.6G73 V74A71-G73 PolarHBondContact O-N 2.79Å; A71-V74 HydrophobicContact CB-CB 3.91Å; A71-V74 HydrophobicContact CB-CG2 3.79Å; A71-V74 VanDerWaalsContact O-CB 3.28Å; A71-V74 WeakPolarHBondContact O-CB 3.39Å; A71-V74 PolarHBondContact O-N 2.88Å
72V97.4Very high97.6Very high67 Ų6734.1 Ų34.141%0.40616%0.155SC..THydrogen-bonded Turntrans-50.1126.5-178.2175.10000111.6V74 Q326 H356 E358V72-V74 VanDerWaalsContact C-N 3.34Å; V72-Q326 HydrophobicContact CG1-CG 4.25Å; V72-H356 HydrophobicContact CG2-CB 3.97Å; V72-E358 VanDerWaalsContact CA-OE1 3.25Å; V72-E358 WeakPolarHBondContact CA-OE1 3.33Å; V72-E358 HydrophobicContact CG1-CG 3.95Å
73G96.8Very high97.6Very high23 Ų2334.2 Ų34.224%0.23716%0.155CC..THydrogen-bonded Turntrans83.7-4.9-177.900000115.8A71 K324 E358 Y360A71-G73 PolarHBondContact O-N 2.79Å; G73-K324 WeakPolarHBondContact O-CE 3.36Å; G73-K324 PolarHBondContact O-NZ 3.29Å; G73-E358 PolarHBondContact N-OE1 3.06Å; G73-Y360 WeakPolarHBondContact CA-OH 3.39Å; G73-Y360 PolarHBondContact N-OH 3.08Å
74V98.4Very high97.6Very high19 Ų1934.3 Ų34.312%0.11516%0.156CC..  trans-96109.8171.3178.30000107.5H70 A71 V72 R120H70-V74 PolarHBondContact CE1-O 3.28Å; A71-V74 HydrophobicContact CB-CB 3.91Å; A71-V74 HydrophobicContact CB-CG2 3.79Å; A71-V74 VanDerWaalsContact O-CB 3.28Å; A71-V74 WeakPolarHBondContact O-CB 3.39Å; A71-V74 PolarHBondContact O-N 2.88Å; V72-V74 VanDerWaalsContact C-N 3.34Å; V74-R120 HydrophobicContact CG1-CB 4.22Å
75P98.6Very high97.6Very high0 Ų034.2 Ų34.20%016%0.155CC..  trans-66.5146.7179.228.6-36.7000112S118 R120 V192 V319 Y360P75-S118 WeakPolarHBondContact CD-O 3.34Å; P75-R120 PolarHBondContact O-N 3.5Å; P75-R120 VanDerWaalsContact O-N 3.12Å; P75-V192 HydrophobicContact CB-CB 4.33Å; P75-V192 HydrophobicContact CB-CG2 3.88Å; P75-V319 HydrophobicContact CB-CG2 3.68Å; P75-V319 HydrophobicContact CG-CG1 3.9Å; P75-V319 HydrophobicContact CG-CG2 4Å; P75-Y360 HydrophobicContact CB-CD1 4.07Å; P75-Y360 HydrophobicContact CB-CE1 3.8Å
76E98.8Very high97.7Very high1 Ų130.7 Ų30.71%0.00514%0.136CC..EExtended strand (participates in β ladder)trans-89.9124.3172-53.2-66.8162.900109H70 R120 H122 E189 T190 F191 V192H70-E76 IonicContact CE1-OE1 3.05Å; H70-E76 IonicContact CG-OE1 3.78Å; H70-E76 IonicContact ND1-OE1 2.95Å; H70-E76 PolarHBondContact ND1-OE1 2.99Å; E76-R120 IonicContact OE1-NH1 2.76Å; E76-R120 PolarHBondContact OE1-NH1 3.26Å; E76-R120 VanDerWaalsContact OE2-CB 3.24Å; E76-R120 WeakPolarHBondContact OE2-CB 3.46Å; E76-R120 VanDerWaalsContact OE2-CD 3.3Å; E76-R120 WeakPolarHBondContact OE2-CD 3.39Å; E76-R120 VanDerWaalsContact OE2-CG 3.22Å; E76-R120 WeakPolarHBondContact OE2-CG 3.48Å; E76-R120 IonicContact OE2-CZ 3.06Å; E76-R120 IonicContact OE2-NE 3.28Å; E76-R120 IonicContact OE2-NH1 3.35Å; E76-R120 PolarHBondContact OE2-NH1 2.89Å; E76-H122 IonicContact OE2-CD2 3.35Å; E76-H122 IonicContact OE2-NE2 3.74Å; E76-H122 PolarHBondContact OE2-NE2 3.33Å; E76-E189 HydrophobicContact CG-CB 4.42Å; E76-T190 WeakPolarHBondContact CB-O 3.32Å; E76-F191 HydrophobicContact CB-CD1 3.86Å; E76-F191 HydrophobicContact CB-CE1 4.15Å; E76-V192 PolarHBondContact O-N 3.31Å
77F98.9Very high97.9Very high0 Ų024.7 Ų24.70%011%0.114CC..EExtended strand (participates in β ladder)trans-112.9148.5174.6173.6-82.2000109.4Y79 T119 R120 I121 H122 L193 Y315 I316 V319F77-Y79 HydrophobicContact CE1-CD1 4.26Å; F77-Y79 AromaticContact CE1-CD2 3.43Å; F77-Y79 HydrophobicContact CE1-CD2 3.43Å; F77-Y79 VanDerWaalsContact CE1-CD2 3.43Å; F77-Y79 HydrophobicContact CE1-CE1 4.48Å; F77-Y79 AromaticContact CE1-CE2 3.68Å; F77-Y79 HydrophobicContact CE1-CE2 3.68Å; F77-Y79 AromaticContact CE1-CG 3.73Å; F77-Y79 HydrophobicContact CE1-CG 3.73Å; F77-Y79 HydrophobicContact CZ-CD1 4.05Å; F77-Y79 AromaticContact CZ-CD2 3.79Å; F77-Y79 HydrophobicContact CZ-CD2 3.79Å; F77-Y79 AromaticContact CZ-CE1 3.91Å; F77-Y79 HydrophobicContact CZ-CE1 3.91Å; F77-Y79 AromaticContact CZ-CE2 3.6Å; F77-Y79 HydrophobicContact CZ-CE2 3.6Å; F77-Y79 AromaticContact CZ-CG 3.99Å; F77-Y79 HydrophobicContact CZ-CG 3.99Å; F77-Y79 AromaticContact CZ-CZ 3.66Å; F77-T119 HydrophobicContact CB-CG2 3.75Å; F77-R120 PolarHBondContact N-O 3.38Å; F77-I121 HydrophobicContact CD1-CG2 3.91Å; F77-I121 HydrophobicContact CE1-CG2 4.47Å; F77-H122 PolarHBondContact O-N 3.02Å; F77-L193 WeakPolarHBondContact CA-O 3.48Å; F77-L193 HydrophobicContact CD2-CB 3.94Å; F77-L193 HydrophobicContact CD2-CD2 4.05Å; F77-L193 HydrophobicContact CD2-CG 4.02Å; F77-L193 WeakPolarHBondContact CD2-O 3.22Å; F77-L193 HydrophobicContact CE2-CB 4.32Å; F77-L193 HydrophobicContact CE2-CD2 3.91Å; F77-L193 HydrophobicContact CE2-CG 3.9Å; F77-Y315 AromaticContact CE2-CD1 3.75Å; F77-Y315 HydrophobicContact CE2-CD1 3.75Å; F77-Y315 AromaticContact CE2-CE1 3.81Å; F77-Y315 HydrophobicContact CE2-CE1 3.81Å; F77-Y315 AromaticContact CZ-CD1 3.87Å; F77-Y315 HydrophobicContact CZ-CD1 3.87Å; F77-Y315 HydrophobicContact CZ-CE1 4.08Å; F77-I316 HydrophobicContact CD1-CG1 4.09Å; F77-I316 HydrophobicContact CD1-CG2 4.2Å; F77-I316 HydrophobicContact CD2-CG2 4.29Å; F77-I316 HydrophobicContact CE1-CD1 4.48Å; F77-I316 HydrophobicContact CE1-CG1 3.64Å; F77-I316 HydrophobicContact CE2-CB 4.38Å; F77-I316 HydrophobicContact CE2-CG1 4.14Å; F77-I316 HydrophobicContact CG-CG2 4.08Å; F77-I316 HydrophobicContact CZ-CB 4.4Å; F77-I316 HydrophobicContact CZ-CG1 3.68Å; F77-V319 HydrophobicContact CB-CG2 4.33Å; F77-V319 HydrophobicContact CD2-CB 4.33Å
78K98.9Very high97.9Very high0 Ų024.2 Ų24.20%011%0.111CC..EExtended strand (participates in β ladder)trans-137.914816963.9178.1174.267.40116.3H122 W185 L186 F191 L193 S194 A195 N277 E285K78-H122 CarbonylContact C-O 3.45Å; K78-H122 WeakPolarHBondContact CA-O 3.31Å; K78-H122 HydrophobicContact CB-CB 4.06Å; K78-W185 HydrophobicContact CB-CH2 3.73Å; K78-W185 HydrophobicContact CB-CZ2 4.12Å; K78-W185 HydrophobicContact CD-CE3 4.38Å; K78-W185 HydrophobicContact CD-CH2 3.48Å; K78-W185 VanDerWaalsContact CD-CH2 3.48Å; K78-W185 HydrophobicContact CD-CZ2 4.02Å; K78-W185 HydrophobicContact CD-CZ3 3.68Å; K78-W185 HydrophobicContact CG-CH2 4.21Å; K78-L186 HydrophobicContact CD-CD2 4.45Å; K78-F191 HydrophobicContact CB-CD1 3.84Å; K78-F191 HydrophobicContact CB-CE1 3.69Å; K78-F191 HydrophobicContact CB-CZ 4.38Å; K78-F191 HydrophobicContact CD-CD1 3.76Å; K78-F191 HydrophobicContact CD-CD2 3.91Å; K78-F191 HydrophobicContact CD-CE1 3.9Å; K78-F191 HydrophobicContact CD-CE2 4.01Å; K78-F191 HydrophobicContact CD-CG 3.78Å; K78-F191 HydrophobicContact CD-CZ 4.04Å; K78-F191 HydrophobicContact CG-CD1 3.75Å; K78-F191 HydrophobicContact CG-CE1 4.03Å; K78-F191 HydrophobicContact CG-CG 4.16Å; K78-L193 PolarHBondContact N-O 2.85Å; K78-L193 VanDerWaalsContact N-O 3.08Å; K78-S194 WeakPolarHBondContact CG-OG 3.34Å; K78-S194 VanDerWaalsContact NZ-CB 3.29Å; K78-S194 PolarHBondContact NZ-OG 3.44Å; K78-S194 WeakPolarHBondContact O-CA 3.33Å; K78-S194 PolarHBondContact O-OG 3Å; K78-A195 PolarHBondContact O-N 2.87Å; K78-N277 VanDerWaalsContact CE-OD1 3.32Å; K78-N277 WeakPolarHBondContact CE-OD1 3.44Å; K78-N277 PolarHBondContact NZ-OD1 2.02Å; K78-E285 IonicContact NZ-OE2 3.97Å; K78-E285 PolarHBondContact NZ-OE2 3.41Å
79Y99Very high98Very high0 Ų016.4 Ų16.40%08%0.082CC..EExtended strand (participates in β ladder)trans-115.1136.5161.7-87.2-51.5000110.4F77 L94 L97 H122 L124 A195 L197 L288 L312 Y315 I316F77-Y79 HydrophobicContact CE1-CD1 4.26Å; F77-Y79 AromaticContact CE1-CD2 3.43Å; F77-Y79 HydrophobicContact CE1-CD2 3.43Å; F77-Y79 VanDerWaalsContact CE1-CD2 3.43Å; F77-Y79 HydrophobicContact CE1-CE1 4.48Å; F77-Y79 AromaticContact CE1-CE2 3.68Å; F77-Y79 HydrophobicContact CE1-CE2 3.68Å; F77-Y79 AromaticContact CE1-CG 3.73Å; F77-Y79 HydrophobicContact CE1-CG 3.73Å; F77-Y79 HydrophobicContact CZ-CD1 4.05Å; F77-Y79 AromaticContact CZ-CD2 3.79Å; F77-Y79 HydrophobicContact CZ-CD2 3.79Å; F77-Y79 AromaticContact CZ-CE1 3.91Å; F77-Y79 HydrophobicContact CZ-CE1 3.91Å; F77-Y79 AromaticContact CZ-CE2 3.6Å; F77-Y79 HydrophobicContact CZ-CE2 3.6Å; F77-Y79 AromaticContact CZ-CG 3.99Å; F77-Y79 HydrophobicContact CZ-CG 3.99Å; F77-Y79 AromaticContact CZ-CZ 3.66Å; Y79-L94 HydrophobicContact CD2-CD2 3.9Å; Y79-L94 HydrophobicContact CG-CD2 3.8Å; Y79-L97 HydrophobicContact CD2-CD2 3.78Å; Y79-L97 HydrophobicContact CE2-CD2 3.94Å; Y79-H122 PolarHBondContact N-O 2.83Å; Y79-L124 PolarHBondContact O-N 3.05Å; Y79-A195 WeakPolarHBondContact CA-O 3.29Å; Y79-A195 HydrophobicContact CD1-CB 3.81Å; Y79-A195 WeakPolarHBondContact CD1-O 3.45Å; Y79-A195 HydrophobicContact CE1-CB 3.47Å; Y79-A195 VanDerWaalsContact CE1-CB 3.47Å; Y79-L197 HydrophobicContact CD1-CD1 3.43Å; Y79-L197 VanDerWaalsContact CD1-CD1 3.43Å; Y79-L197 HydrophobicContact CE1-CD1 3.82Å; Y79-L197 HydrophobicContact CG-CD1 4.29Å; Y79-L288 HydrophobicContact CE1-CD1 4.18Å; Y79-L312 HydrophobicContact CE1-CD2 4.13Å; Y79-L312 HydrophobicContact CE2-CB 4.39Å; Y79-L312 HydrophobicContact CE2-CD2 3.79Å; Y79-L312 WeakPolarHBondContact OH-CA 3.25Å; Y79-L312 PolarHBondContact OH-O 3.32Å; Y79-Y315 HydrophobicContact CE1-CD1 4.02Å; Y79-Y315 HydrophobicContact CE1-CE1 4.35Å; Y79-Y315 AromaticContact CZ-CD1 3.83Å; Y79-Y315 WeakPolarHBondContact OH-CB 3.37Å; Y79-Y315 WeakPolarHBondContact OH-CD1 3.39Å; Y79-I316 HydrophobicContact CD2-CG1 4.45Å; Y79-I316 HydrophobicContact CE2-CD1 4Å; Y79-I316 HydrophobicContact CE2-CG1 3.74Å
80V99Very high98.2Very high1 Ų17.7 Ų7.71%0.0065%0.049CC..EExtended strand (participates in β ladder)trans-121.8137.9172.6-178.80000108.4L124 M127 W185 A195 N196 L197 M273V80-L124 HydrophobicContact CG1-CD2 3.93Å; V80-L124 HydrophobicContact CG1-CG 4.33Å; V80-L124 HydrophobicContact CG2-CB 4.35Å; V80-L124 HydrophobicContact CG2-CD2 4.31Å; V80-M127 HydrophobicContact CG1-CB 3.99Å; V80-M127 HydrophobicContact CG1-SD 4.28Å; V80-W185 HydrophobicContact CG2-CH2 4.33Å; V80-W185 HydrophobicContact CG2-CZ3 3.83Å; V80-A195 PolarHBondContact N-O 3.31Å; V80-N196 HydrophobicContact CB-CB 4.38Å; V80-N196 CarbonylContact O-C 3.54Å; V80-N196 VanDerWaalsContact O-CA 3.24Å; V80-N196 WeakPolarHBondContact O-CA 3.39Å; V80-L197 PolarHBondContact O-N 3.16Å; V80-M273 HydrophobicContact CB-CE 4.16Å; V80-M273 HydrophobicContact CG1-CE 3.96Å
81A98.9Very high98.3Very high1 Ų16.2 Ų6.21%0.0084%0.042CC..EExtended strand (participates in β ladder)trans-135.1165.8173.600000112.1M83 G90 L94 L124 T126 M127 L197A81-M83 PolarHBondContact O-N 3.26Å; A81-G90 VanDerWaalsContact CB-C 3.41Å; A81-L94 HydrophobicContact CB-CD1 3.46Å; A81-L94 VanDerWaalsContact CB-CD1 3.46Å; A81-L94 HydrophobicContact CB-CG 4.09Å; A81-L124 PolarHBondContact N-O 3.26Å; A81-T126 WeakPolarHBondContact O-CA 3.4Å; A81-M127 PolarHBondContact O-N 3.01Å; A81-L197 HydrophobicContact CB-CB 3.91Å; A81-L197 HydrophobicContact CB-CD2 4.46Å
82N98.8Very high98.4Very high0 Ų06.2 Ų6.20%04%0.042CC..  trans56.743.4167.5-173.7-127.9000111.4H84 G85 E87 R91 T126 N128N82-H84 VanDerWaalsContact C-N 3.27Å; N82-H84 PolarHBondContact ND2-O 3.37Å; N82-G85 VanDerWaalsContact ND2-C 3.34Å; N82-G85 WeakPolarHBondContact ND2-CA 3.41Å; N82-G85 PolarHBondContact ND2-O 3.07Å; N82-E87 PolarHBondContact ND2-O 3.09Å; N82-E87 VanDerWaalsContact ND2-O 3.14Å; N82-R91 HydrophobicContact CB-CB 3.91Å; N82-R91 PolarHBondContact OD1-NH1 3.04Å; N82-T126 PolarHBondContact OD1-OG1 2.82Å; N82-N128 WeakPolarHBondContact O-CB 3.26Å; N82-N128 PolarHBondContact O-N 3.28Å
83M98.8Very high98.5Very high2 Ų23 Ų31%0.012%0.022CC..SBendtrans-73.1-26.216774.3178.1-53.500111.5A81 M127 N128 L153 N154 F157 H198 M273A81-M83 PolarHBondContact O-N 3.26Å; M83-M127 HydrophobicContact CB-CB 4.02Å; M83-M127 HydrophobicContact CB-CG 4.19Å; M83-M127 HydrophobicContact CB-SD 3.64Å; M83-M127 HydrophobicContact CE-CE 4.48Å; M83-M127 HydrophobicContact CE-SD 4.14Å; M83-N128 WeakPolarHBondContact O-CB 3.46Å; M83-N128 PolarHBondContact O-ND2 2.99Å; M83-L153 HydrophobicContact CE-CB 4.09Å; M83-N154 VanDerWaalsContact CE-CA 3.49Å; M83-N154 HydrophobicContact CE-CB 3.39Å; M83-N154 HydrophobicContact SD-CB 3.78Å; M83-F157 HydrophobicContact CE-CE2 4.35Å; M83-H198 WeakPolarHBondContact CG-CE1 3.41Å; M83-H198 WeakPolarHBondContact CG-NE2 3.23Å; M83-H198 PolarHBondContact SD-CE1 3.42Å; M83-H198 PolarHBondContact SD-NE2 3.04Å; M83-M273 HydrophobicContact CE-CB 4.2Å; M83-M273 HydrophobicContact CE-CE 4.29Å; M83-M273 HydrophobicContact SD-CE 3.94Å
84H98.6Very high98.6Very high3 Ų32 Ų21%0.0141%0.011CC..SBendtrans-96.2121.9156.6-58.8136.8000108.8N82 N86 E87 R145 D152 H198N82-H84 VanDerWaalsContact C-N 3.27Å; N82-H84 PolarHBondContact ND2-O 3.37Å; H84-N86 VanDerWaalsContact C-N 3.26Å; H84-N86 PolarHBondContact O-N 3.43Å; H84-E87 HydrophobicContact CB-CB 4.09Å; H84-E87 VanDerWaalsContact CB-CD 3.46Å; H84-E87 HydrophobicContact CB-CG 3.89Å; H84-E87 WeakPolarHBondContact CB-OE1 3.45Å; H84-E87 IonicContact CE1-OE1 2.71Å; H84-E87 IonicContact CG-OE1 2.63Å; H84-E87 IonicContact CG-OE2 3.28Å; H84-E87 IonicContact ND1-OE1 3.07Å; H84-E87 PolarHBondContact ND1-OE1 2.95Å; H84-E87 IonicContact ND1-OE2 3.79Å; H84-E87 PolarHBondContact ND1-OE2 2.73Å; H84-E87 PolarHBondContact O-N 3.37Å; H84-E87 VanDerWaalsContact O-N 3.09Å; H84-R145 VanDerWaalsContact CA-O 3.28Å; H84-R145 WeakPolarHBondContact CA-O 3.47Å; H84-R145 HydrophobicContact CB-CG 3.85Å; H84-R145 PolarHBondContact CE1-NH1 3.03Å; H84-R145 PolarHBondContact CE1-NH2 3.47Å; H84-R145 PolarHBondContact ND1-NH1 3.3Å; H84-R145 VanDerWaalsContact NE2-CZ 3.34Å; H84-R145 PolarHBondContact NE2-NH2 3.33Å; H84-R145 VanDerWaalsContact NE2-NH2 3.17Å; H84-D152 IonicContact CD2-OD1 2.81Å; H84-D152 IonicContact NE2-OD1 2.94Å; H84-D152 PolarHBondContact NE2-OD1 3.01Å; H84-D152 VanDerWaalsContact NE2-OD1 3.11Å; H84-D152 IonicContact NE2-OD2 3.46Å; H84-H198 AromaticContact CE1-CE1 3.31Å; H84-H198 PolarHBondContact CE1-CE1 3.36Å; H84-H198 AromaticContact CE1-ND1 3.57Å; H84-H198 AromaticContact ND1-CE1 3.33Å; H84-H198 PolarHBondContact ND1-CE1 2.96Å; H84-H198 VanDerWaalsContact ND1-CE1 3.33Å; H84-H198 AromaticContact ND1-ND1 3.26Å; H84-H198 PolarHBondContact ND1-ND1 3.32Å
85G97.9Very high98.6Very high0 Ų01.2 Ų1.20%01%0.006CC..THydrogen-bonded Turntrans-63.7-29.7-170.200000114.2N82 V88 F132 G144 R145N82-G85 VanDerWaalsContact ND2-C 3.34Å; N82-G85 WeakPolarHBondContact ND2-CA 3.41Å; N82-G85 PolarHBondContact ND2-O 3.07Å; G85-V88 WeakPolarHBondContact O-CG1 3.35Å; G85-F132 WeakPolarHBondContact O-CA 3.12Å; G85-G144 CarbonylContact C-O 3.11Å; G85-G144 WeakPolarHBondContact CA-O 3.34Å; G85-G144 PolarHBondContact N-O 3.28Å; G85-R145 PolarHBondContact N-O 3.03Å
86N97.9Very high98.6Very high0 Ų01.9 Ų1.90%01%0.009CC..THydrogen-bonded Turntrans-87.7-1.8177.470.8-29.1000115H84 V88 A135 M141 Q143 G144 R145 K294H84-N86 VanDerWaalsContact C-N 3.26Å; H84-N86 PolarHBondContact O-N 3.43Å; N86-V88 PolarHBondContact O-N 2.95Å; N86-A135 HydrophobicContact CB-CB 3.8Å; N86-M141 PolarHBondContact ND2-O 3.04Å; N86-Q143 VanDerWaalsContact CB-O 3.25Å; N86-Q143 WeakPolarHBondContact CB-O 3.3Å; N86-G144 PolarHBondContact N-O 3.48Å; N86-R145 VanDerWaalsContact OD1-CA 3.24Å; N86-R145 WeakPolarHBondContact OD1-CA 3.27Å; N86-R145 WeakPolarHBondContact OD1-CB 3.16Å; N86-K294 CarbonylContact O-C 3.54Å; N86-K294 WeakPolarHBondContact O-CB 3.27Å; N86-K294 VanDerWaalsContact O-O 3.1Å
87E98.2Very high98.6Very high4 Ų41.9 Ų1.92%0.0191%0.009CC..  trans-97.185.2174.1-67.4170-153.600108.1N82 H84 R145 H198 G199 K294N82-E87 PolarHBondContact ND2-O 3.09Å; N82-E87 VanDerWaalsContact ND2-O 3.14Å; H84-E87 HydrophobicContact CB-CB 4.09Å; H84-E87 VanDerWaalsContact CB-CD 3.46Å; H84-E87 HydrophobicContact CB-CG 3.89Å; H84-E87 WeakPolarHBondContact CB-OE1 3.45Å; H84-E87 IonicContact CE1-OE1 2.71Å; H84-E87 IonicContact CG-OE1 2.63Å; H84-E87 IonicContact CG-OE2 3.28Å; H84-E87 IonicContact ND1-OE1 3.07Å; H84-E87 PolarHBondContact ND1-OE1 2.95Å; H84-E87 IonicContact ND1-OE2 3.79Å; H84-E87 PolarHBondContact ND1-OE2 2.73Å; H84-E87 PolarHBondContact O-N 3.37Å; H84-E87 VanDerWaalsContact O-N 3.09Å; E87-R145 IonicContact OE1-CZ 2.72Å; E87-R145 IonicContact OE1-NH1 2.91Å; E87-R145 PolarHBondContact OE1-NH1 2.79Å; E87-H198 WeakPolarHBondContact OE2-CB 3.31Å; E87-H198 IonicContact OE2-CE1 2.88Å; E87-H198 IonicContact OE2-CG 3.06Å; E87-H198 IonicContact OE2-ND1 3.55Å; E87-H198 PolarHBondContact OE2-ND1 3.27Å; E87-G199 VanDerWaalsContact CG-O 3.3Å; E87-G199 WeakPolarHBondContact CG-O 3.39Å; E87-G199 PolarHBondContact OE2-N 3.05Å; E87-K294 HydrophobicContact CG-CB 4.2Å; E87-K294 HydrophobicContact CG-CD 4.15Å; E87-K294 HydrophobicContact CG-CG 4.07Å
88V97.8Very high98.6Very high0 Ų01.9 Ų1.90%01%0.009CC..  trans-99.3-14.5-158-62.50000114.9Y22 G85 N86 G90 R91 V92 F132 K294 F295Y22-V88 HydrophobicContact CD1-CB 4.4Å; Y22-V88 HydrophobicContact CD1-CG2 4.2Å; Y22-V88 HydrophobicContact CE1-CB 3.98Å; Y22-V88 HydrophobicContact CE1-CG2 3.39Å; G85-V88 WeakPolarHBondContact O-CG1 3.35Å; N86-V88 PolarHBondContact O-N 2.95Å; V88-G90 VanDerWaalsContact C-N 3.34Å; V88-G90 PolarHBondContact O-N 3.44Å; V88-R91 WeakPolarHBondContact O-CB 3.46Å; V88-R91 PolarHBondContact O-N 3.31Å; V88-V92 PolarHBondContact O-N 3.29Å; V88-F132 HydrophobicContact CG1-CD2 3.74Å; V88-F132 HydrophobicContact CG1-CE2 3.79Å; V88-K294 PolarHBondContact N-O 3.49Å; V88-K294 VanDerWaalsContact N-O 3.09Å; V88-F295 HydrophobicContact CB-CD2 4.34Å; V88-F295 HydrophobicContact CB-CE2 4.31Å; V88-F295 HydrophobicContact CG1-CD2 3.56Å; V88-F295 HydrophobicContact CG1-CE2 3.38Å; V88-F295 HydrophobicContact CG1-CG 4.26Å; V88-F295 HydrophobicContact CG1-CZ 3.94Å; V88-F295 HydrophobicContact CG2-CB 4.18Å; V88-F295 HydrophobicContact CG2-CD1 3.69Å; V88-F295 HydrophobicContact CG2-CD2 3.79Å; V88-F295 HydrophobicContact CG2-CE1 3.97Å; V88-F295 HydrophobicContact CG2-CE2 4.07Å; V88-F295 HydrophobicContact CG2-CG 3.59Å; V88-F295 HydrophobicContact CG2-CZ 4.14Å
89L98.4Very high98.6Very high2 Ų23.1 Ų3.11%0.012%0.02CC..Hα-helixtrans-60.1-46.5-176.9-179.656.7000111.1R91 V92 L93 L290 S291 L301 L304L89-R91 VanDerWaalsContact C-N 3.26Å; L89-R91 PolarHBondContact O-N 3.48Å; L89-V92 PolarHBondContact O-N 3.05Å; L89-L93 HydrophobicContact CD1-CD1 4.47Å; L89-L93 HydrophobicContact CD1-CD2 3.89Å; L89-L93 HydrophobicContact CD1-CG 3.96Å; L89-L93 HydrophobicContact CG-CD1 4.11Å; L89-L93 HydrophobicContact CG-CD2 4.41Å; L89-L93 HydrophobicContact CG-CG 4.01Å; L89-L93 WeakPolarHBondContact O-CG 3.26Å; L89-L93 PolarHBondContact O-N 2.9Å; L89-L290 HydrophobicContact CD2-CB 3.8Å; L89-L290 HydrophobicContact CG-CB 4.42Å; L89-S291 WeakPolarHBondContact CD2-OG 3.43Å; L89-L301 HydrophobicContact CD1-CD2 4.05Å; L89-L304 HydrophobicContact CD1-CB 3.84Å; L89-L304 HydrophobicContact CD1-CD1 3.9Å; L89-L304 HydrophobicContact CD1-CG 4.48Å; L89-L304 HydrophobicContact CD2-CB 4.18Å; L89-L304 HydrophobicContact CD2-CD1 4.08Å; L89-L304 HydrophobicContact CD2-CD2 4.25Å; L89-L304 HydrophobicContact CD2-CG 4.4Å
90G98.8Very high98.5Very high0 Ų04.1 Ų4.10%03%0.025CC..Hα-helixtrans-56.3-38.8178.400000113.3A81 V88 V92 L93 L94A81-G90 VanDerWaalsContact CB-C 3.41Å; V88-G90 VanDerWaalsContact C-N 3.34Å; V88-G90 PolarHBondContact O-N 3.44Å; G90-V92 VanDerWaalsContact C-N 3.32Å; G90-V92 PolarHBondContact O-N 2.67Å; G90-L93 PolarHBondContact O-N 3.03Å; G90-L94 WeakPolarHBondContact O-CB 3.5Å; G90-L94 WeakPolarHBondContact O-CG 3.38Å; G90-L94 PolarHBondContact O-N 3.07Å
91R98.4Very high98.5Very high3 Ų34.1 Ų4.11%0.0112%0.024CC..Hα-helixtrans-56.9-46.1175.4-178.1-176.6173.6104.21.4111.3H23 D24 N25 I28 N82 V88 L89 L95 P125 T126H23-R91 PolarHBondContact O-NE 2.95Å; H23-R91 PolarHBondContact O-NH2 3.46Å; D24-R91 VanDerWaalsContact C-NH2 3.29Å; D24-R91 PolarHBondContact O-NH2 3.35Å; N25-R91 VanDerWaalsContact OD1-CZ 3.27Å; N25-R91 PolarHBondContact OD1-NH1 3.37Å; N25-R91 PolarHBondContact OD1-NH2 2.74Å; I28-R91 HydrophobicContact CD1-CG 3.75Å; N82-R91 HydrophobicContact CB-CB 3.91Å; N82-R91 PolarHBondContact OD1-NH1 3.04Å; V88-R91 WeakPolarHBondContact O-CB 3.46Å; V88-R91 PolarHBondContact O-N 3.31Å; L89-R91 VanDerWaalsContact C-N 3.26Å; L89-R91 PolarHBondContact O-N 3.48Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 2.88Å; R91-P125 WeakPolarHBondContact CA-O 3.22Å; R91-T126 PolarHBondContact NH1-OG1 3.05Å; R91-T126 VanDerWaalsContact NH1-OG1 3.08Å
92V98.6Very high98.5Very high5 Ų54.4 Ų4.43%0.033%0.026CC..Hα-helixtrans-69.6-46.6178.7179.20000111.1Y22 V88 L89 G90 L94 L95 Q96 L301Y22-V92 HydrophobicContact CD1-CG2 3.86Å; Y22-V92 HydrophobicContact CE1-CG2 3.92Å; V88-V92 PolarHBondContact O-N 3.29Å; L89-V92 PolarHBondContact O-N 3.05Å; G90-V92 VanDerWaalsContact C-N 3.32Å; G90-V92 PolarHBondContact O-N 2.67Å; V92-L94 VanDerWaalsContact C-N 3.28Å; V92-L94 PolarHBondContact O-N 2.99Å; V92-L95 PolarHBondContact O-N 3.24Å; V92-Q96 HydrophobicContact CG1-CG 4.33Å; V92-Q96 WeakPolarHBondContact O-CG 3.48Å; V92-Q96 PolarHBondContact O-N 2.82Å; V92-L301 HydrophobicContact CG1-CD1 4.34Å; V92-L301 HydrophobicContact CG1-CD2 4.38Å; V92-L301 HydrophobicContact CG2-CD1 4.39Å; V92-L301 HydrophobicContact CG2-CD2 4.34Å
93L98.9Very high98.4Very high0 Ų08.8 Ų8.80%04%0.043CC..Hα-helixtrans-60.7-38-177.9-62.6-169.7000112.2L89 G90 Q96 L97 L290 W305 N308 L312L89-L93 HydrophobicContact CD1-CD1 4.47Å; L89-L93 HydrophobicContact CD1-CD2 3.89Å; L89-L93 HydrophobicContact CD1-CG 3.96Å; L89-L93 HydrophobicContact CG-CD1 4.11Å; L89-L93 HydrophobicContact CG-CD2 4.41Å; L89-L93 HydrophobicContact CG-CG 4.01Å; L89-L93 WeakPolarHBondContact O-CG 3.26Å; L89-L93 PolarHBondContact O-N 2.9Å; G90-L93 PolarHBondContact O-N 3.03Å; L93-Q96 PolarHBondContact O-N 3.37Å; L93-L97 WeakPolarHBondContact O-CB 3.39Å; L93-L97 PolarHBondContact O-N 3.28Å; L93-L290 HydrophobicContact CD1-CD1 3.68Å; L93-W305 HydrophobicContact CD2-CB 4.07Å; L93-W305 HydrophobicContact CD2-CE3 3.96Å; L93-W305 WeakPolarHBondContact O-CZ3 3.39Å; L93-N308 HydrophobicContact CD1-CB 3.65Å; L93-L312 HydrophobicContact CB-CD1 4.21Å; L93-L312 HydrophobicContact CD1-CD1 4.39Å
94L98.9Very high98.4Very high0 Ų08.7 Ų8.70%04%0.042CC..Hα-helixtrans-69.3-34.7179.3-70.9-167.8000112.9Y79 A81 G90 V92 L97 I98 I123 L197Y79-L94 HydrophobicContact CD2-CD2 3.9Å; Y79-L94 HydrophobicContact CG-CD2 3.8Å; A81-L94 HydrophobicContact CB-CD1 3.46Å; A81-L94 VanDerWaalsContact CB-CD1 3.46Å; A81-L94 HydrophobicContact CB-CG 4.09Å; G90-L94 WeakPolarHBondContact O-CB 3.5Å; G90-L94 WeakPolarHBondContact O-CG 3.38Å; G90-L94 PolarHBondContact O-N 3.07Å; V92-L94 VanDerWaalsContact C-N 3.28Å; V92-L94 PolarHBondContact O-N 2.99Å; L94-L97 HydrophobicContact CD2-CD2 4.19Å; L94-L97 PolarHBondContact O-N 3.16Å; L94-I98 WeakPolarHBondContact O-CG1 3.19Å; L94-I98 PolarHBondContact O-N 3.15Å; L94-I123 HydrophobicContact CB-CG2 3.66Å; L94-I123 HydrophobicContact CD1-CG2 3.95Å; L94-I123 HydrophobicContact CD2-CG2 4.31Å; L94-I123 HydrophobicContact CG-CG2 4.16Å; L94-L197 HydrophobicContact CD1-CD2 4.43Å; L94-L197 HydrophobicContact CD2-CD2 3.82Å; L94-L197 HydrophobicContact CG-CD2 3.95Å
95L98.8Very high98.3Very high3 Ų311.5 Ų11.52%0.0165%0.053CC..Hα-helixtrans-67.7-40.6171.7-58.7172000111.6L18 H23 I28 Y31 L32 R91 V92 L97 I98 A99 P125L18-L95 HydrophobicContact CD2-CB 3.44Å; L18-L95 VanDerWaalsContact CD2-CB 3.44Å; H23-L95 HydrophobicContact CB-CD1 4.47Å; I28-L95 HydrophobicContact CD1-CD1 3.71Å; I28-L95 HydrophobicContact CD1-CD2 4.26Å; I28-L95 HydrophobicContact CD1-CG 4.35Å; I28-L95 HydrophobicContact CG1-CD1 3.81Å; I28-L95 HydrophobicContact CG1-CD2 4.35Å; I28-L95 HydrophobicContact CG2-CD2 4.16Å; Y31-L95 HydrophobicContact CD1-CD2 3.89Å; Y31-L95 HydrophobicContact CE1-CB 4.37Å; Y31-L95 HydrophobicContact CE1-CD2 4.01Å; Y31-L95 PolarHBondContact OH-O 2.9Å; L32-L95 HydrophobicContact CD2-CD2 4.33Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 2.88Å; V92-L95 PolarHBondContact O-N 3.24Å; L95-L97 VanDerWaalsContact C-N 3.32Å; L95-L97 PolarHBondContact O-N 2.89Å; L95-I98 WeakPolarHBondContact O-CB 3.49Å; L95-I98 PolarHBondContact O-N 2.94Å; L95-A99 PolarHBondContact O-N 3Å; L95-P125 HydrophobicContact CD2-CB 4.01Å; L95-P125 HydrophobicContact CD2-CG 3.89Å; L95-P125 HydrophobicContact CG-CB 4.41Å
96Q98.7Very high98.3Very high15 Ų1516.1 Ų16.17%0.077%0.07CC..Hα-helixtrans-66.4-35176.6-66.7-67.4-17.800112L18 E19 F20 V92 L93 A99 E100 W305L18-Q96 HydrophobicContact CD2-CG 4.31Å; L18-Q96 PolarHBondContact O-NE2 3.11Å; E19-Q96 PolarHBondContact O-NE2 3.47Å; F20-Q96 HydrophobicContact CD1-CG 4.3Å; F20-Q96 HydrophobicContact CE1-CG 3.67Å; F20-Q96 HydrophobicContact CZ-CG 4.21Å; V92-Q96 HydrophobicContact CG1-CG 4.33Å; V92-Q96 WeakPolarHBondContact O-CG 3.48Å; V92-Q96 PolarHBondContact O-N 2.82Å; L93-Q96 PolarHBondContact O-N 3.37Å; Q96-A99 PolarHBondContact O-N 2.86Å; Q96-E100 WeakPolarHBondContact O-CB 3.46Å; Q96-E100 PolarHBondContact O-N 2.73Å; Q96-W305 HydrophobicContact CB-CD2 3.78Å; Q96-W305 HydrophobicContact CB-CE3 3.58Å; Q96-W305 HydrophobicContact CB-CG 4.47Å; Q96-W305 HydrophobicContact CB-CH2 4.12Å; Q96-W305 HydrophobicContact CB-CZ2 4.25Å; Q96-W305 HydrophobicContact CB-CZ3 3.77Å
97L98.8Very high98.2Very high0 Ų020.3 Ų20.30%09%0.093CC..Hα-helixtrans-64.4-42.1172.3179.763.4000112.3Y79 L93 L94 L95 A99 E100 L101 I123 W305 L312 L313 I316Y79-L97 HydrophobicContact CD2-CD2 3.78Å; Y79-L97 HydrophobicContact CE2-CD2 3.94Å; L93-L97 WeakPolarHBondContact O-CB 3.39Å; L93-L97 PolarHBondContact O-N 3.28Å; L94-L97 HydrophobicContact CD2-CD2 4.19Å; L94-L97 PolarHBondContact O-N 3.16Å; L95-L97 VanDerWaalsContact C-N 3.32Å; L95-L97 PolarHBondContact O-N 2.89Å; L97-A99 VanDerWaalsContact C-N 3.34Å; L97-E100 PolarHBondContact O-N 2.91Å; L97-L101 HydrophobicContact CD1-CD1 4.24Å; L97-L101 HydrophobicContact CD1-CG 4.26Å; L97-L101 HydrophobicContact CG-CD1 4.08Å; L97-L101 WeakPolarHBondContact O-CG 3.2Å; L97-L101 PolarHBondContact O-N 2.86Å; L97-I123 HydrophobicContact CD2-CD1 3.96Å; L97-I123 HydrophobicContact CG-CD1 4.18Å; L97-W305 HydrophobicContact CB-CH2 4.16Å; L97-W305 HydrophobicContact CB-CZ3 4.17Å; L97-W305 HydrophobicContact CD1-CH2 4.49Å; L97-L312 HydrophobicContact CD2-CB 4.49Å; L97-L313 HydrophobicContact CD1-CD2 3.83Å; L97-L313 HydrophobicContact CD1-CG 4.37Å; L97-I316 HydrophobicContact CD2-CD1 4.18Å
98I98.8Very high98.2Very high0 Ų025.8 Ų25.80%012%0.122CC..Hα-helixtrans-57-50.3172.2-70.7166.2000110Y31 L32 V35 L61 L63 L94 L95 E100 L101 V102 I123Y31-I98 HydrophobicContact CE1-CG2 4.18Å; L32-I98 HydrophobicContact CD2-CD1 3.65Å; V35-I98 HydrophobicContact CG1-CG2 3.93Å; L61-I98 HydrophobicContact CB-CD1 4.24Å; L61-I98 HydrophobicContact CD2-CB 4.42Å; L61-I98 HydrophobicContact CD2-CD1 3.89Å; L61-I98 HydrophobicContact CD2-CG1 4.04Å; L61-I98 HydrophobicContact CD2-CG2 3.49Å; L61-I98 VanDerWaalsContact CD2-CG2 3.49Å; L63-I98 HydrophobicContact CD1-CG1 4.43Å; L94-I98 WeakPolarHBondContact O-CG1 3.19Å; L94-I98 PolarHBondContact O-N 3.15Å; L95-I98 WeakPolarHBondContact O-CB 3.49Å; L95-I98 PolarHBondContact O-N 2.94Å; I98-E100 VanDerWaalsContact C-N 3.3Å; I98-E100 PolarHBondContact O-N 2.67Å; I98-L101 PolarHBondContact O-N 2.83Å; I98-V102 WeakPolarHBondContact O-CB 3.44Å; I98-V102 WeakPolarHBondContact O-CG2 3.31Å; I98-V102 PolarHBondContact O-N 2.93Å; I98-I123 HydrophobicContact CD1-CB 4.21Å; I98-I123 HydrophobicContact CD1-CD1 4.46Å; I98-I123 HydrophobicContact CD1-CG2 3.86Å; I98-I123 HydrophobicContact CG1-CB 4.31Å; I98-I123 HydrophobicContact CG1-CD1 3.64Å; I98-I123 HydrophobicContact CG1-CG2 4.14Å
99A98.2Very high98.2Very high27 Ų2729.5 Ų29.522%0.22314%0.14CC..Hα-helixtrans-58.1-42.9178.800000111.9L18 Y31 L95 Q96 L97 R103L18-A99 HydrophobicContact CB-CB 4.39Å; Y31-A99 PolarHBondContact OH-N 2.85Å; L95-A99 PolarHBondContact O-N 3Å; Q96-A99 PolarHBondContact O-N 2.86Å; L97-A99 VanDerWaalsContact C-N 3.34Å; A99-R103 WeakPolarHBondContact O-CB 3.35Å; A99-R103 PolarHBondContact O-N 2.77Å
100E98.1Very high98.1Very high21 Ų2133.9 Ų33.910%0.09817%0.167CC..Hα-helixtrans-67.4-42.2-179.6-177.762-166.100113Q96 L97 I98 R103 G104 W111 W305 K309Q96-E100 WeakPolarHBondContact O-CB 3.46Å; Q96-E100 PolarHBondContact O-N 2.73Å; L97-E100 PolarHBondContact O-N 2.91Å; I98-E100 VanDerWaalsContact C-N 3.3Å; I98-E100 PolarHBondContact O-N 2.67Å; E100-R103 IonicContact OE1-CZ 3.93Å; E100-R103 IonicContact OE1-NE 3.33Å; E100-R103 IonicContact OE1-NH2 3.74Å; E100-R103 PolarHBondContact OE1-NH2 3.05Å; E100-R103 IonicContact OE2-CZ 3.85Å; E100-R103 IonicContact OE2-NE 2.79Å; E100-R103 PolarHBondContact OE2-NE 3.47Å; E100-R103 IonicContact OE2-NH2 3.74Å; E100-R103 PolarHBondContact OE2-NH2 2.95Å; E100-G104 PolarHBondContact O-N 2.86Å; E100-W111 HydrophobicContact CG-CH2 4.02Å; E100-W111 HydrophobicContact CG-CZ2 4.44Å; E100-W305 HydrophobicContact CB-CH2 4.24Å; E100-W305 HydrophobicContact CB-CZ2 3.99Å; E100-W305 HydrophobicContact CG-CZ2 4.28Å; E100-K309 VanDerWaalsContact CD-CE 3.42Å; E100-K309 VanDerWaalsContact OE1-CE 3.23Å; E100-K309 WeakPolarHBondContact OE1-CE 3.46Å; E100-K309 IonicContact OE1-NZ 3.65Å; E100-K309 PolarHBondContact OE1-NZ 2.76Å; E100-K309 IonicContact OE2-NZ 3.87Å; E100-K309 PolarHBondContact OE2-NZ 3.11Å
101L98.5Very high98Very high0 Ų037 Ų370%018%0.179CC..Hα-helixtrans-63.9-46.7176.7-72.3167.5000111.2L63 L97 I98 G104 Y105 W111 S112 L115 I121 I123 L313L63-L101 HydrophobicContact CD2-CB 4.15Å; L63-L101 HydrophobicContact CD2-CD1 4.27Å; L97-L101 HydrophobicContact CD1-CD1 4.24Å; L97-L101 HydrophobicContact CD1-CG 4.26Å; L97-L101 HydrophobicContact CG-CD1 4.08Å; L97-L101 WeakPolarHBondContact O-CG 3.2Å; L97-L101 PolarHBondContact O-N 2.86Å; I98-L101 PolarHBondContact O-N 2.83Å; L101-G104 PolarHBondContact O-N 3.39Å; L101-Y105 PolarHBondContact O-N 2.81Å; L101-W111 HydrophobicContact CD2-CZ3 4.06Å; L101-S112 PolarHBondContact O-OG 2.7Å; L101-L115 HydrophobicContact CD2-CD2 3.96Å; L101-I121 HydrophobicContact CD1-CD1 4.12Å; L101-I121 HydrophobicContact CD2-CD1 4.37Å; L101-I123 HydrophobicContact CD1-CD1 4.35Å; L101-L313 HydrophobicContact CD2-CD2 4.19Å
102V98.3Very high98Very high7 Ų736.9 Ų36.94%0.04218%0.178CC..Hα-helixtrans-63.5-44.5177.7168.40000111.2V35 N39 I42 T43 L63 I98 Y105 R106V35-V102 HydrophobicContact CG1-CG2 4.04Å; N39-V102 WeakPolarHBondContact OD1-CG1 3.37Å; I42-V102 HydrophobicContact CD1-CG2 4.23Å; T43-V102 HydrophobicContact CG2-CG2 4.42Å; L63-V102 HydrophobicContact CD2-CG2 4.19Å; I98-V102 WeakPolarHBondContact O-CB 3.44Å; I98-V102 WeakPolarHBondContact O-CG2 3.31Å; I98-V102 PolarHBondContact O-N 2.93Å; V102-Y105 PolarHBondContact O-N 3.13Å; V102-R106 WeakPolarHBondContact O-CG 3.32Å; V102-R106 PolarHBondContact O-N 2.77Å
103R97.4Very high98Very high93 Ų9339.4 Ų39.435%0.35119%0.191SC..Hα-helixtrans-59.3-50.5175.3-174.5-169.369.875.2-2110.6A99 E100 Y105 R106 D107A99-R103 WeakPolarHBondContact O-CB 3.35Å; A99-R103 PolarHBondContact O-N 2.77Å; E100-R103 IonicContact OE1-CZ 3.93Å; E100-R103 IonicContact OE1-NE 3.33Å; E100-R103 IonicContact OE1-NH2 3.74Å; E100-R103 PolarHBondContact OE1-NH2 3.05Å; E100-R103 IonicContact OE2-CZ 3.85Å; E100-R103 IonicContact OE2-NE 2.79Å; E100-R103 PolarHBondContact OE2-NE 3.47Å; E100-R103 IonicContact OE2-NH2 3.74Å; E100-R103 PolarHBondContact OE2-NH2 2.95Å; R103-Y105 VanDerWaalsContact C-N 3.27Å; R103-Y105 PolarHBondContact O-N 3.42Å; R103-R106 PolarHBondContact O-N 3.12Å; R103-R106 VanDerWaalsContact O-N 3.16Å; R103-D107 WeakPolarHBondContact CG-OD2 3.34Å; R103-D107 IonicContact CZ-OD2 3.8Å; R103-D107 IonicContact NH1-OD2 3.97Å; R103-D107 PolarHBondContact NH1-OD2 2.82Å; R103-D107 WeakPolarHBondContact O-CB 3.46Å; R103-D107 VanDerWaalsContact O-CG 3.25Å; R103-D107 PolarHBondContact O-N 2.89Å
104G97.8Very high97.9Very high0 Ų043.5 Ų43.50%021%0.21CC..Hα-helixtrans-58.4-37.6177.900000113E100 L101 N108 E109E100-G104 PolarHBondContact O-N 2.86Å; L101-G104 PolarHBondContact O-N 3.39Å; G104-N108 PolarHBondContact O-N 2.99Å; G104-E109 WeakPolarHBondContact O-CB 3.19Å; G104-E109 PolarHBondContact O-N 3.34Å
105Y97.7Very high97.9Very high61 Ų6143.5 Ų43.524%0.23921%0.21CC..Hα-helixtrans-65-49174.5178-99.4000112I42 L65 L101 V102 R103 D107 N108 S112 L113 L116I42-Y105 HydrophobicContact CD1-CD1 3.57Å; I42-Y105 HydrophobicContact CD1-CD2 4.36Å; I42-Y105 HydrophobicContact CD1-CE1 4.24Å; I42-Y105 HydrophobicContact CD1-CG 3.64Å; I42-Y105 HydrophobicContact CG1-CD1 3.99Å; I42-Y105 HydrophobicContact CG1-CE1 4.16Å; I42-Y105 HydrophobicContact CG1-CG 4.35Å; I42-Y105 HydrophobicContact CG2-CD1 4.04Å; I42-Y105 HydrophobicContact CG2-CD2 3.72Å; I42-Y105 HydrophobicContact CG2-CE1 3.71Å; I42-Y105 HydrophobicContact CG2-CE2 3.39Å; I42-Y105 HydrophobicContact CG2-CG 4.05Å; L65-Y105 HydrophobicContact CD2-CE2 3.98Å; L101-Y105 PolarHBondContact O-N 2.81Å; V102-Y105 PolarHBondContact O-N 3.13Å; R103-Y105 VanDerWaalsContact C-N 3.27Å; R103-Y105 PolarHBondContact O-N 3.42Å; Y105-D107 VanDerWaalsContact C-N 3.28Å; Y105-D107 PolarHBondContact O-N 3.12Å; Y105-N108 PolarHBondContact O-N 2.98Å; Y105-N108 VanDerWaalsContact O-N 3.09Å; Y105-S112 PolarHBondContact N-OG 3.32Å; Y105-L113 HydrophobicContact CD2-CD2 3.56Å; Y105-L113 HydrophobicContact CE2-CD2 3.84Å; Y105-L116 HydrophobicContact CD2-CD1 4.08Å; Y105-L116 HydrophobicContact CG-CD1 4.29Å
106R96.5Very high97.8Very high98 Ų9843.4 Ų43.437%0.3721%0.21SC..Hα-helixtrans-62.4-36.3179.8-72.9174.5173.3-179.6-9.4112.6D38 N39 V102 R103 N108D38-R106 PolarHBondContact O-NH2 3.11Å; N39-R106 VanDerWaalsContact CG-NH2 3.27Å; N39-R106 PolarHBondContact ND2-NH2 2.88Å; N39-R106 PolarHBondContact OD1-NE 3.3Å; N39-R106 PolarHBondContact OD1-NH2 2.86Å; V102-R106 WeakPolarHBondContact O-CG 3.32Å; V102-R106 PolarHBondContact O-N 2.77Å; R103-R106 PolarHBondContact O-N 3.12Å; R103-R106 VanDerWaalsContact O-N 3.16Å; R106-N108 PolarHBondContact O-N 3.43Å
107D97.5Very high97.8Very high87 Ų8747.5 Ų47.547%0.46523%0.232SC..THydrogen-bonded Turntrans-80.60.2179.3-65-11.1000112.4R103 Y105 E109R103-D107 WeakPolarHBondContact CG-OD2 3.34Å; R103-D107 IonicContact CZ-OD2 3.8Å; R103-D107 IonicContact NH1-OD2 3.97Å; R103-D107 PolarHBondContact NH1-OD2 2.82Å; R103-D107 WeakPolarHBondContact O-CB 3.46Å; R103-D107 VanDerWaalsContact O-CG 3.25Å; R103-D107 PolarHBondContact O-N 2.89Å; Y105-D107 VanDerWaalsContact C-N 3.28Å; Y105-D107 PolarHBondContact O-N 3.12Å; D107-E109 HydrophobicContact CB-CG 3.97Å; D107-E109 PolarHBondContact O-N 3.49Å
108N97.3Very high97.8Very high120 Ų12048.3 Ų48.364%0.64224%0.237SC*.THydrogen-bonded Turntrans55.435.9-174.1-64.7-61.3000113.7G104 Y105 R106 T110 L113G104-N108 PolarHBondContact O-N 2.99Å; Y105-N108 PolarHBondContact O-N 2.98Å; Y105-N108 VanDerWaalsContact O-N 3.09Å; R106-N108 PolarHBondContact O-N 3.43Å; N108-T110 PolarHBondContact O-N 3.38Å; N108-L113 HydrophobicContact CB-CD1 4.37Å
109E98Very high97.8Very high78 Ų7848.3 Ų48.336%0.36424%0.237SC..  trans-68.8126.7177.4-69.3-71.6173.800110.7G104 D107 W111 S112 L113G104-E109 WeakPolarHBondContact O-CB 3.19Å; G104-E109 PolarHBondContact O-N 3.34Å; D107-E109 HydrophobicContact CB-CG 3.97Å; D107-E109 PolarHBondContact O-N 3.49Å; E109-W111 VanDerWaalsContact C-N 3.3Å; E109-W111 PolarHBondContact O-N 2.86Å; E109-S112 PolarHBondContact O-N 2.94Å; E109-S112 VanDerWaalsContact O-N 3.11Å; E109-L113 WeakPolarHBondContact O-CG 3.22Å; E109-L113 PolarHBondContact O-N 3.27Å
110T97.4Very high97.8Very high94 Ų9447.4 Ų47.458%0.57723%0.228SC*.Hα-helixtrans-57.9-42-172.7-61.80000112.2N108 S112 Q114N108-T110 PolarHBondContact O-N 3.38Å; T110-S112 VanDerWaalsContact C-N 3.35Å; T110-S112 PolarHBondContact O-N 3.39Å; T110-Q114 HydrophobicContact CG2-CG 4.31Å; T110-Q114 WeakPolarHBondContact O-CB 3.35Å; T110-Q114 VanDerWaalsContact O-CG 3.25Å; T110-Q114 WeakPolarHBondContact O-CG 3.19Å; T110-Q114 PolarHBondContact O-N 2.97Å
111W96.4Very high97.9Very high66 Ų6646.4 Ų46.425%0.2522%0.224CC..Hα-helixtrans-63.9-38.2-179.467.5-94.5000112.4E100 L101 E109 L115 L313E100-W111 HydrophobicContact CG-CH2 4.02Å; E100-W111 HydrophobicContact CG-CZ2 4.44Å; L101-W111 HydrophobicContact CD2-CZ3 4.06Å; E109-W111 VanDerWaalsContact C-N 3.3Å; E109-W111 PolarHBondContact O-N 2.86Å; W111-L115 WeakPolarHBondContact O-CB 3.42Å; W111-L115 PolarHBondContact O-N 2.92Å; W111-L115 VanDerWaalsContact O-N 3.09Å; W111-L313 HydrophobicContact CE3-CD2 4.48Å; W111-L313 HydrophobicContact CH2-CD1 4.46Å; W111-L313 HydrophobicContact CZ3-CD1 4.14Å; W111-L313 HydrophobicContact CZ3-CD2 3.8Å
112S97.8Very high97.9Very high0 Ų046.4 Ų46.40%022%0.224CC..Hα-helixtrans-74.3-44.6-179-176.20000110.4L101 Y105 E109 T110 Q114 L115 L116L101-S112 PolarHBondContact O-OG 2.7Å; Y105-S112 PolarHBondContact N-OG 3.32Å; E109-S112 PolarHBondContact O-N 2.94Å; E109-S112 VanDerWaalsContact O-N 3.11Å; T110-S112 VanDerWaalsContact C-N 3.35Å; T110-S112 PolarHBondContact O-N 3.39Å; S112-Q114 VanDerWaalsContact C-N 3.33Å; S112-Q114 PolarHBondContact O-N 3.43Å; S112-L115 PolarHBondContact O-N 2.8Å; S112-L116 WeakPolarHBondContact O-CB 3.48Å; S112-L116 WeakPolarHBondContact O-CG 3.46Å; S112-L116 PolarHBondContact O-N 2.91Å
113L97.8Very high97.9Very high58 Ų5846 Ų4630%0.30422%0.222SC..Hα-helixtrans-59.6-43.4175.6-66.8178.4000111.9Y105 N108 E109 N117Y105-L113 HydrophobicContact CD2-CD2 3.56Å; Y105-L113 HydrophobicContact CE2-CD2 3.84Å; N108-L113 HydrophobicContact CB-CD1 4.37Å; E109-L113 WeakPolarHBondContact O-CG 3.22Å; E109-L113 PolarHBondContact O-N 3.27Å; L113-N117 WeakPolarHBondContact O-CB 3.38Å; L113-N117 PolarHBondContact O-N 2.79Å
114Q97.6Very high98Very high85 Ų8541.6 Ų41.640%0.39721%0.205SC..Hα-helixtrans-61.4-49176.2-76.3176.8-36.700111.2T110 S112 N117 S118 Y393T110-Q114 HydrophobicContact CG2-CG 4.31Å; T110-Q114 WeakPolarHBondContact O-CB 3.35Å; T110-Q114 VanDerWaalsContact O-CG 3.25Å; T110-Q114 WeakPolarHBondContact O-CG 3.19Å; T110-Q114 PolarHBondContact O-N 2.97Å; S112-Q114 VanDerWaalsContact C-N 3.33Å; S112-Q114 PolarHBondContact O-N 3.43Å; Q114-N117 PolarHBondContact O-N 3.36Å; Q114-S118 WeakPolarHBondContact O-CB 3.39Å; Q114-S118 PolarHBondContact O-N 3.3Å; Q114-S118 PolarHBondContact O-OG 3.5Å; Q114-Y393 HydrophobicContact CB-CD1 4Å; Q114-Y393 HydrophobicContact CB-CD2 3.92Å; Q114-Y393 HydrophobicContact CB-CE1 3.83Å; Q114-Y393 HydrophobicContact CB-CE2 3.76Å; Q114-Y393 HydrophobicContact CB-CG 4.03Å; Q114-Y393 HydrophobicContact CG-CD2 4.41Å; Q114-Y393 HydrophobicContact CG-CE2 4.26Å
115L98.1Very high98Very high1 Ų141.7 Ų41.71%0.00521%0.205CC..Hα-helixtrans-64.7-44.7-177.8-165.867.4000112.8L101 W111 S112 N117 S118 T119 I121 L313 I316 Q317 Y393L101-L115 HydrophobicContact CD2-CD2 3.96Å; W111-L115 WeakPolarHBondContact O-CB 3.42Å; W111-L115 PolarHBondContact O-N 2.92Å; W111-L115 VanDerWaalsContact O-N 3.09Å; S112-L115 PolarHBondContact O-N 2.8Å; L115-N117 VanDerWaalsContact C-N 3.33Å; L115-N117 PolarHBondContact O-N 2.97Å; L115-S118 PolarHBondContact O-N 2.85Å; L115-S118 PolarHBondContact O-OG 2.86Å; L115-T119 WeakPolarHBondContact O-CB 3.47Å; L115-T119 PolarHBondContact O-N 3.13Å; L115-I121 HydrophobicContact CD2-CD1 4.06Å; L115-I121 HydrophobicContact CG-CD1 4.1Å; L115-L313 HydrophobicContact CD2-CD2 4.27Å; L115-I316 HydrophobicContact CD1-CB 4.48Å; L115-I316 HydrophobicContact CD1-CG2 3.86Å; L115-I316 HydrophobicContact CD2-CB 4.49Å; L115-I316 HydrophobicContact CD2-CD1 4.47Å; L115-I316 HydrophobicContact CD2-CG2 4.15Å; L115-I316 HydrophobicContact CG-CG2 4.25Å; L115-Q317 HydrophobicContact CD1-CG 3.89Å; L115-Y393 HydrophobicContact CB-CD1 4.48Å; L115-Y393 HydrophobicContact CB-CE1 4.02Å; L115-Y393 HydrophobicContact CD1-CD1 4.13Å; L115-Y393 HydrophobicContact CD1-CE1 3.91Å
116L98.3Very high98.1Very high1 Ų139.1 Ų39.11%0.00520%0.196CC..Hα-helixtrans-73.8-22.6179.7-66.6176.1000113.2I42 L63 G64 L65 Y105 S112 I121I42-L116 HydrophobicContact CD1-CD1 4.24Å; L63-L116 HydrophobicContact CB-CD2 3.82Å; G64-L116 CarbonylContact C-O 3.56Å; G64-L116 VanDerWaalsContact CA-O 3.24Å; G64-L116 WeakPolarHBondContact CA-O 3.25Å; L65-L116 PolarHBondContact N-O 2.98Å; Y105-L116 HydrophobicContact CD2-CD1 4.08Å; Y105-L116 HydrophobicContact CG-CD1 4.29Å; S112-L116 WeakPolarHBondContact O-CB 3.48Å; S112-L116 WeakPolarHBondContact O-CG 3.46Å; S112-L116 PolarHBondContact O-N 2.91Å; L116-I121 HydrophobicContact CD2-CD1 4.17Å
117N98Very high98.2Very high101 Ų10134.5 Ų34.554%0.5418%0.178SC..Hα-helixtrans-79.4-37172.7-178.440.2000111.9L65 L113 Q114 L115L65-N117 HydrophobicContact CD1-CB 3.69Å; L65-N117 WeakPolarHBondContact CD1-OD1 3.33Å; L65-N117 HydrophobicContact CG-CB 4.21Å; L113-N117 WeakPolarHBondContact O-CB 3.38Å; L113-N117 PolarHBondContact O-N 2.79Å; Q114-N117 PolarHBondContact O-N 3.36Å; L115-N117 VanDerWaalsContact C-N 3.33Å; L115-N117 PolarHBondContact O-N 2.97Å
118S98.4Very high98.3Very high16 Ų1630.3 Ų30.311%0.11216%0.156CC..Hα-helixtrans-89.6-20.6-173.767.90000114.5P75 Q114 L115 H320 Y393P75-S118 WeakPolarHBondContact CD-O 3.34Å; Q114-S118 WeakPolarHBondContact O-CB 3.39Å; Q114-S118 PolarHBondContact O-N 3.3Å; Q114-S118 PolarHBondContact O-OG 3.5Å; L115-S118 PolarHBondContact O-N 2.85Å; L115-S118 PolarHBondContact O-OG 2.86Å; S118-H320 PolarHBondContact O-CE1 3.14Å; S118-H320 PolarHBondContact OG-CE1 3.45Å; S118-H320 PolarHBondContact OG-NE2 2.95Å; S118-Y393 VanDerWaalsContact CB-O 3.25Å; S118-Y393 WeakPolarHBondContact CB-O 3.1Å
119T98.8Very high98.3Very high0 Ų024.7 Ų24.70%013%0.126CC..  trans-136.6145.5-172.2-57.30000110.7F77 L115 I121 I316 V319 H320F77-T119 HydrophobicContact CB-CG2 3.75Å; L115-T119 WeakPolarHBondContact O-CB 3.47Å; L115-T119 PolarHBondContact O-N 3.13Å; T119-I121 HydrophobicContact CG2-CG1 3.78Å; T119-I316 HydrophobicContact CG2-CG2 4.4Å; T119-V319 HydrophobicContact CG2-CG1 3.92Å; T119-H320 PolarHBondContact OG1-CE1 3.31Å; T119-H320 PolarHBondContact OG1-NE2 3.41Å
120R98.8Very high98.3Very high8 Ų821 Ų213%0.0311%0.109CC..EExtended strand (participates in β ladder)trans-104.2113.9164.7-176.9168.6171.4-111.46108.8L63 P67 V74 P75 E76 F77 H122 E189L63-R120 WeakPolarHBondContact O-CA 3.4Å; P67-R120 PolarHBondContact O-NE 3.16Å; P67-R120 PolarHBondContact O-NH2 3.28Å; V74-R120 HydrophobicContact CG1-CB 4.22Å; P75-R120 PolarHBondContact O-N 3.5Å; P75-R120 VanDerWaalsContact O-N 3.12Å; E76-R120 IonicContact OE1-NH1 2.76Å; E76-R120 PolarHBondContact OE1-NH1 3.26Å; E76-R120 VanDerWaalsContact OE2-CB 3.24Å; E76-R120 WeakPolarHBondContact OE2-CB 3.46Å; E76-R120 VanDerWaalsContact OE2-CD 3.3Å; E76-R120 WeakPolarHBondContact OE2-CD 3.39Å; E76-R120 VanDerWaalsContact OE2-CG 3.22Å; E76-R120 WeakPolarHBondContact OE2-CG 3.48Å; E76-R120 IonicContact OE2-CZ 3.06Å; E76-R120 IonicContact OE2-NE 3.28Å; E76-R120 IonicContact OE2-NH1 3.35Å; E76-R120 PolarHBondContact OE2-NH1 2.89Å; F77-R120 PolarHBondContact N-O 3.38Å; R120-H122 PolarHBondContact NH1-CE1 3.22Å; R120-H122 VanDerWaalsContact NH1-CE1 3.34Å; R120-H122 PolarHBondContact NH1-NE2 3.5Å; R120-H122 VanDerWaalsContact NH1-NE2 3.18Å; R120-E189 IonicContact CZ-OE1 3.88Å; R120-E189 IonicContact NH1-OE1 3.24Å; R120-E189 PolarHBondContact NH1-OE1 3.47Å; R120-E189 IonicContact NH1-OE2 3.95Å; R120-E189 PolarHBondContact NH1-OE2 2.92Å; R120-E189 IonicContact NH2-OE1 2.89Å; R120-E189 PolarHBondContact NH2-OE1 3.05Å
121I98.9Very high98.3Very high0 Ų016.5 Ų16.50%08%0.082CC..EExtended strand (participates in β ladder)trans-103.2123.9-169-55.5170.1000108.1A62 L63 F77 L101 L115 L116 T119 I123 I316A62-I121 CarbonylContact C-O 3.52Å; A62-I121 VanDerWaalsContact CA-O 3.3Å; A62-I121 WeakPolarHBondContact CA-O 3.3Å; L63-I121 HydrophobicContact CB-CB 4.49Å; L63-I121 PolarHBondContact N-O 2.83Å; L63-I121 PolarHBondContact O-N 2.73Å; F77-I121 HydrophobicContact CD1-CG2 3.91Å; F77-I121 HydrophobicContact CE1-CG2 4.47Å; L101-I121 HydrophobicContact CD1-CD1 4.12Å; L101-I121 HydrophobicContact CD2-CD1 4.37Å; L115-I121 HydrophobicContact CD2-CD1 4.06Å; L115-I121 HydrophobicContact CG-CD1 4.1Å; L116-I121 HydrophobicContact CD2-CD1 4.17Å; T119-I121 HydrophobicContact CG2-CG1 3.78Å; I121-I123 HydrophobicContact CG2-CD1 4.22Å; I121-I123 HydrophobicContact CG2-CG1 4.02Å; I121-I316 HydrophobicContact CD1-CD1 4.42Å; I121-I316 HydrophobicContact CD1-CG2 3.99Å; I121-I316 HydrophobicContact CG1-CG2 4.07Å
122H98.9Very high98.4Very high0 Ų014.5 Ų14.50%08%0.075CC..EExtended strand (participates in β ladder)trans-110.2128176.7-63.4-111.5000111.1Y46 V60 E76 F77 K78 Y79 R120 W185 F191Y46-H122 AromaticContact CE1-ND1 3.93Å; Y46-H122 AromaticContact CZ-ND1 3.74Å; Y46-H122 PolarHBondContact OH-CE1 3.42Å; Y46-H122 PolarHBondContact OH-ND1 3.11Å; V60-H122 HydrophobicContact CG1-CB 3.91Å; E76-H122 IonicContact OE2-CD2 3.35Å; E76-H122 IonicContact OE2-NE2 3.74Å; E76-H122 PolarHBondContact OE2-NE2 3.33Å; F77-H122 PolarHBondContact O-N 3.02Å; K78-H122 CarbonylContact C-O 3.45Å; K78-H122 WeakPolarHBondContact CA-O 3.31Å; K78-H122 HydrophobicContact CB-CB 4.06Å; Y79-H122 PolarHBondContact N-O 2.83Å; R120-H122 PolarHBondContact NH1-CE1 3.22Å; R120-H122 VanDerWaalsContact NH1-CE1 3.34Å; R120-H122 PolarHBondContact NH1-NE2 3.5Å; R120-H122 VanDerWaalsContact NH1-NE2 3.18Å; H122-W185 HydrophobicContact CB-CH2 4.29Å; H122-W185 HydrophobicContact CB-CZ2 3.64Å; H122-F191 HydrophobicContact CB-CE1 4.07Å; H122-F191 HydrophobicContact CB-CZ 4.39Å; H122-F191 AromaticContact CD2-CE1 3.65Å; H122-F191 AromaticContact CG-CE1 3.81Å
123I98.9Very high98.3Very high0 Ų018.4 Ų18.40%010%0.096CC..EExtended strand (participates in β ladder)trans-121117.4-176.9-61.6-177.9000109V60 L61 L63 L94 L97 I98 L101 I121 P125V60-I123 WeakPolarHBondContact CA-O 3.28Å; L61-I123 PolarHBondContact N-O 3Å; L61-I123 PolarHBondContact O-N 3.43Å; L63-I123 HydrophobicContact CD1-CD1 3.84Å; L63-I123 HydrophobicContact CD1-CG1 4.14Å; L94-I123 HydrophobicContact CB-CG2 3.66Å; L94-I123 HydrophobicContact CD1-CG2 3.95Å; L94-I123 HydrophobicContact CD2-CG2 4.31Å; L94-I123 HydrophobicContact CG-CG2 4.16Å; L97-I123 HydrophobicContact CD2-CD1 3.96Å; L97-I123 HydrophobicContact CG-CD1 4.18Å; I98-I123 HydrophobicContact CD1-CB 4.21Å; I98-I123 HydrophobicContact CD1-CD1 4.46Å; I98-I123 HydrophobicContact CD1-CG2 3.86Å; I98-I123 HydrophobicContact CG1-CB 4.31Å; I98-I123 HydrophobicContact CG1-CD1 3.64Å; I98-I123 HydrophobicContact CG1-CG2 4.14Å; L101-I123 HydrophobicContact CD1-CD1 4.35Å; I121-I123 HydrophobicContact CG2-CD1 4.22Å; I121-I123 HydrophobicContact CG2-CG1 4.02Å; I123-P125 HydrophobicContact CG2-CG 4.25Å; I123-P125 WeakPolarHBondContact O-CD 3.39Å
124L98.9Very high98.2Very high0 Ų018.7 Ų18.70%010%0.095CC..EExtended strand (participates in β ladder)trans-105.795.2170.8176.155.7000108.7I48 L58 W59 V60 Y79 V80 A81 T126 M127 V182 W185I48-L124 HydrophobicContact CD1-CD2 3.85Å; L58-L124 HydrophobicContact CB-CD1 4.35Å; W59-L124 WeakPolarHBondContact O-CD1 3.42Å; V60-L124 HydrophobicContact CG2-CB 4.08Å; V60-L124 HydrophobicContact CG2-CD1 4.03Å; V60-L124 HydrophobicContact CG2-CG 4.49Å; Y79-L124 PolarHBondContact O-N 3.05Å; V80-L124 HydrophobicContact CG1-CD2 3.93Å; V80-L124 HydrophobicContact CG1-CG 4.33Å; V80-L124 HydrophobicContact CG2-CB 4.35Å; V80-L124 HydrophobicContact CG2-CD2 4.31Å; A81-L124 PolarHBondContact N-O 3.26Å; L124-T126 VanDerWaalsContact C-N 3.28Å; L124-T126 VanDerWaalsContact CD1-O 3.32Å; L124-T126 WeakPolarHBondContact CD1-O 3.5Å; L124-T126 PolarHBondContact O-N 2.61Å; L124-M127 HydrophobicContact CD2-CB 4.14Å; L124-V182 HydrophobicContact CD2-CG2 4.34Å; L124-W185 HydrophobicContact CB-CH2 4.42Å; L124-W185 HydrophobicContact CB-CZ3 4.41Å; L124-W185 HydrophobicContact CD2-CZ3 4.15Å
125P98.8Very high98.1Very high1 Ų115.6 Ų15.61%0.0068%0.084CC..SBendtrans-66.7-28.2-174.5-22.435000113.9I28 L32 W59 R91 L95 I123I28-P125 HydrophobicContact CD1-CB 4.47Å; L32-P125 HydrophobicContact CD1-CG 4.33Å; W59-P125 WeakPolarHBondContact O-CD 3.48Å; R91-P125 WeakPolarHBondContact CA-O 3.22Å; L95-P125 HydrophobicContact CD2-CB 4.01Å; L95-P125 HydrophobicContact CD2-CG 3.89Å; L95-P125 HydrophobicContact CG-CB 4.41Å; I123-P125 HydrophobicContact CG2-CG 4.25Å; I123-P125 WeakPolarHBondContact O-CD 3.39Å
126T98.7Very high97.8Very high8 Ų816.6 Ų16.65%0.0499%0.09CC..  trans-145.2115.4179.1-174.70000110.8A81 N82 R91 L124 P129A81-T126 WeakPolarHBondContact O-CA 3.4Å; N82-T126 PolarHBondContact OD1-OG1 2.82Å; R91-T126 PolarHBondContact NH1-OG1 3.05Å; R91-T126 VanDerWaalsContact NH1-OG1 3.08Å; L124-T126 VanDerWaalsContact C-N 3.28Å; L124-T126 VanDerWaalsContact CD1-O 3.32Å; L124-T126 WeakPolarHBondContact CD1-O 3.5Å; L124-T126 PolarHBondContact O-N 2.61Å; T126-P129 HydrophobicContact CG2-CB 4.12Å
127M98.8Very high97.4Very high0 Ų021.4 Ų21.40%012%0.119CC..SBendtrans-84.5-29.6170.9176.9-179.3174.400111.5V80 A81 M83 L124 P129 L153 F157 E178 V179 V182 M273V80-M127 HydrophobicContact CG1-CB 3.99Å; V80-M127 HydrophobicContact CG1-SD 4.28Å; A81-M127 PolarHBondContact O-N 3.01Å; M83-M127 HydrophobicContact CB-CB 4.02Å; M83-M127 HydrophobicContact CB-CG 4.19Å; M83-M127 HydrophobicContact CB-SD 3.64Å; M83-M127 HydrophobicContact CE-CE 4.48Å; M83-M127 HydrophobicContact CE-SD 4.14Å; L124-M127 HydrophobicContact CD2-CB 4.14Å; M127-P129 VanDerWaalsContact C-CD 3.41Å; M127-P129 VanDerWaalsContact O-CD 3.3Å; M127-P129 WeakPolarHBondContact O-CD 3.41Å; M127-L153 HydrophobicContact CE-CB 4.34Å; M127-L153 HydrophobicContact CE-CD1 4.16Å; M127-L153 HydrophobicContact CG-CD1 4.31Å; M127-F157 HydrophobicContact CE-CE2 3.94Å; M127-F157 HydrophobicContact CE-CZ 3.85Å; M127-E178 HydrophobicContact CE-CB 4.28Å; M127-E178 HydrophobicContact CG-CB 4.44Å; M127-E178 WeakPolarHBondContact O-CG 3.43Å; M127-V179 HydrophobicContact CE-CG2 4.43Å; M127-V182 HydrophobicContact CE-CB 4.27Å; M127-V182 HydrophobicContact CE-CG2 3.7Å; M127-V182 HydrophobicContact CG-CG2 4.14Å; M127-V182 HydrophobicContact SD-CG2 3.87Å; M127-M273 HydrophobicContact CE-SD 4.48Å; M127-M273 HydrophobicContact SD-CE 4.47Å; M127-M273 HydrophobicContact SD-SD 3.95Å
128N98.7Very high96.9Very high0 Ų019.8 Ų19.80%011%0.11CC..  trans-119.970.5-179.8-173.28000111.7N82 M83 D130 G131 F132 R145 A146 N147 L153N82-N128 WeakPolarHBondContact O-CB 3.26Å; N82-N128 PolarHBondContact O-N 3.28Å; M83-N128 WeakPolarHBondContact O-CB 3.46Å; M83-N128 PolarHBondContact O-ND2 2.99Å; N128-D130 PolarHBondContact O-N 3.32Å; N128-G131 PolarHBondContact O-N 2.82Å; N128-G131 PolarHBondContact OD1-N 2.95Å; N128-F132 PolarHBondContact O-N 2.82Å; N128-R145 PolarHBondContact ND2-O 2.83Å; N128-A146 VanDerWaalsContact ND2-C 3.27Å; N128-A146 PolarHBondContact ND2-O 2.96Å; N128-N147 PolarHBondContact ND2-N 3.13Å; N128-N147 WeakPolarHBondContact OD1-CA 3.31Å; N128-L153 HydrophobicContact CB-CD1 3.71Å
129P98.4Very high96.4Very high2 Ų221.2 Ų21.21%0.01312%0.12CC..Hα-helixtrans-63.1-32.1179.426.2-34.6000112.3N25 Q56 L58 T126 M127 F132 D133N25-P129 WeakPolarHBondContact ND2-CB 3.42Å; N25-P129 PolarHBondContact ND2-O 2.79Å; N25-P129 WeakPolarHBondContact OD1-CB 3.22Å; Q56-P129 HydrophobicContact CB-CB 4.29Å; Q56-P129 HydrophobicContact CB-CG 3.99Å; L58-P129 HydrophobicContact CD1-CG 4.38Å; T126-P129 HydrophobicContact CG2-CB 4.12Å; M127-P129 VanDerWaalsContact C-CD 3.41Å; M127-P129 VanDerWaalsContact O-CD 3.3Å; M127-P129 WeakPolarHBondContact O-CD 3.41Å; P129-F132 WeakPolarHBondContact O-CB 3.5Å; P129-F132 PolarHBondContact O-N 3.26Å; P129-D133 PolarHBondContact O-N 3.24Å; P129-D133 VanDerWaalsContact O-N 3.13Å
130D98.3Very high95.8Very high0 Ų026.7 Ų26.70%015%0.149CC..Hα-helixtrans-68.3-43.6179.9-60.1-15.5000112.2S51 V52 K53 Q56 N128 F132 D133 E134 H148S51-D130 VanDerWaalsContact CB-CG 3.46Å; S51-D130 VanDerWaalsContact CB-OD1 3.3Å; S51-D130 WeakPolarHBondContact CB-OD1 3.24Å; S51-D130 WeakPolarHBondContact CB-OD2 3.3Å; S51-D130 VanDerWaalsContact OG-CG 3.23Å; S51-D130 PolarHBondContact OG-OD1 3.35Å; S51-D130 PolarHBondContact OG-OD2 2.76Å; V52-D130 PolarHBondContact N-OD2 3.18Å; V52-D130 VanDerWaalsContact N-OD2 3.09Å; K53-D130 HydrophobicContact CB-CB 4.05Å; K53-D130 VanDerWaalsContact CB-OD2 3.29Å; K53-D130 WeakPolarHBondContact CB-OD2 3.38Å; K53-D130 PolarHBondContact N-OD2 3.37Å; Q56-D130 PolarHBondContact NE2-OD1 2.88Å; N128-D130 PolarHBondContact O-N 3.32Å; D130-F132 VanDerWaalsContact C-N 3.25Å; D130-F132 PolarHBondContact O-N 3.15Å; D130-D133 PolarHBondContact O-N 3.45Å; D130-E134 PolarHBondContact O-N 3.21Å; D130-H148 HydrophobicContact CB-CB 3.99Å
131G97.8Very high95.1Very high0 Ų031.1 Ų31.10%017%0.171CC..Hα-helixtrans-62.3-35.7174.700000111.7N128 E134 A135 G144 A146N128-G131 PolarHBondContact O-N 2.82Å; N128-G131 PolarHBondContact OD1-N 2.95Å; G131-E134 CarbonylContact O-C 3.52Å; G131-E134 PolarHBondContact O-N 3.36Å; G131-A135 WeakPolarHBondContact O-CB 3.5Å; G131-A135 PolarHBondContact O-N 3.43Å; G131-G144 CarbonylContact C-O 3.53Å; G131-G144 WeakPolarHBondContact CA-O 3.49Å; G131-G144 CarbonylContact O-C 3.6Å; G131-G144 WeakPolarHBondContact O-CA 3.32Å; G131-A146 WeakPolarHBondContact CA-O 3.46Å
132F97.4Very high94.4Very high24 Ų2435.1 Ų35.111%0.10520%0.199CC..Hα-helixtrans-63.5-43.7175.3174-91.5000112G85 V88 N128 P129 D130 E134 A135 F295G85-F132 WeakPolarHBondContact O-CA 3.12Å; V88-F132 HydrophobicContact CG1-CD2 3.74Å; V88-F132 HydrophobicContact CG1-CE2 3.79Å; N128-F132 PolarHBondContact O-N 2.82Å; P129-F132 WeakPolarHBondContact O-CB 3.5Å; P129-F132 PolarHBondContact O-N 3.26Å; D130-F132 VanDerWaalsContact C-N 3.25Å; D130-F132 PolarHBondContact O-N 3.15Å; F132-E134 PolarHBondContact O-N 2.92Å; F132-A135 WeakPolarHBondContact O-CB 3.3Å; F132-A135 PolarHBondContact O-N 3.4Å; F132-F295 HydrophobicContact CE2-CZ 4.46Å
133D96.7Very high94.2Very high82 Ų8240.5 Ų40.544%0.43922%0.224SC..Hα-helixtrans-62.8-25.1177.1-71.7-27.6000112.7N25 Q56 P129 D130N25-D133 PolarHBondContact ND2-OD1 2.87Å; N25-D133 PolarHBondContact ND2-OD2 2.88Å; Q56-D133 PolarHBondContact NE2-OD2 3.49Å; Q56-D133 PolarHBondContact OE1-OD2 3.44Å; P129-D133 PolarHBondContact O-N 3.24Å; P129-D133 VanDerWaalsContact O-N 3.13Å; D130-D133 PolarHBondContact O-N 3.45Å
134E95.7Very high94Very high63 Ų6341 Ų4129%0.29423%0.229SC..Hα-helixtrans-98.3-4.9-179.8-65.4-179.7-169.100113.5K53 D130 G131 F132 Q143 H148K53-E134 IonicContact NZ-OE1 3.29Å; K53-E134 PolarHBondContact NZ-OE1 3.06Å; D130-E134 PolarHBondContact O-N 3.21Å; G131-E134 CarbonylContact O-C 3.52Å; G131-E134 PolarHBondContact O-N 3.36Å; F132-E134 PolarHBondContact O-N 2.92Å; E134-Q143 WeakPolarHBondContact O-CG 3.34Å; E134-Q143 PolarHBondContact O-NE2 3.11Å; E134-H148 IonicContact OE1-CE1 2.86Å; E134-H148 IonicContact OE1-ND1 3.82Å; E134-H148 PolarHBondContact OE1-ND1 2.74Å
135A95.4Very high94Very high20 Ų2043.4 Ų43.417%0.16524%0.238CC..  trans-68137.3-175.100000112N86 G131 F132 F295N86-A135 HydrophobicContact CB-CB 3.8Å; G131-A135 WeakPolarHBondContact O-CB 3.5Å; G131-A135 PolarHBondContact O-N 3.43Å; F132-A135 WeakPolarHBondContact O-CB 3.3Å; F132-A135 PolarHBondContact O-N 3.4Å; A135-F295 HydrophobicContact CB-CE2 4.15Å
136D90.1Very high93.9Very high23 Ų2344.7 Ų44.712%0.12325%0.249CC..  trans-73.3161.1161.167.443.5000109.8N138 M141 Q143 F295D136-N138 PolarHBondContact O-N 3.45Å; D136-N138 WeakPolarHBondContact OD1-CB 3.4Å; D136-N138 PolarHBondContact OD1-N 2.93Å; D136-M141 WeakPolarHBondContact OD2-CB 3.2Å; D136-Q143 HydrophobicContact CB-CB 4.13Å; D136-Q143 WeakPolarHBondContact OD2-CB 3.47Å; D136-F295 WeakPolarHBondContact O-CD2 3.3Å; D136-F295 WeakPolarHBondContact O-CE2 3.16Å
137T90.4Very high93.9Very high101 Ų10144.4 Ų44.462%0.6225%0.247SC*.SBendtrans-94.131.2176.265.80000111.4F295T137-F295 HydrophobicContact CG2-CD1 4.4Å; T137-F295 HydrophobicContact CG2-CE1 3.92Å; T137-F295 HydrophobicContact CG2-CE2 4.43Å; T137-F295 HydrophobicContact CG2-CZ 3.96Å
138N87.6Confident93.8Very high67 Ų6748 Ų4836%0.35826%0.263SS..  trans-93.3153.1-177.8-167.6-72.3000111.1D136 L140 M141 F295D136-N138 PolarHBondContact O-N 3.45Å; D136-N138 WeakPolarHBondContact OD1-CB 3.4Å; D136-N138 PolarHBondContact OD1-N 2.93Å; N138-L140 PolarHBondContact OD1-N 2.86Å; N138-M141 HydrophobicContact CB-CB 3.95Å; N138-M141 HydrophobicContact CB-CG 3.95Å; N138-M141 HydrophobicContact CB-SD 4.05Å; N138-M141 PolarHBondContact OD1-N 2.86Å; N138-F295 VanDerWaalsContact O-CB 3.26Å; N138-F295 WeakPolarHBondContact O-CB 3.46Å
139C89Confident93.7Very high47 Ų4752.4 Ų52.432%0.31829%0.287SS..SBendtrans-70-37.8-177.6-1570000114C293 K294C139-C293 WeakPolarHBondContact CA-SG 3.42Å; C139-C293 HydrophobicContact CB-CB 4.34Å; C139-C293 WeakPolarHBondContact CB-SG 3.36Å; C139-C293 WeakPolarHBondContact SG-CA 3.48Å; C139-C293 WeakPolarHBondContact SG-CB 3.44Å; C139-C293 CovalentContact SG-SG 2.04Å; C139-C293 PolarHBondContact SG-SG 2.97Å; C139-K294 WeakPolarHBondContact O-CB 3.43Å; C139-K294 PolarHBondContact O-N 3.17Å
140L85.6Confident93.6Very high115 Ų11555.1 Ų55.160%0.60232%0.315SS*.SBendtrans-121.2-22-167.6-61.3177.8000114N138N138-L140 PolarHBondContact OD1-N 2.86Å
141M83.2Confident93.5Very high101 Ų10157.4 Ų57.450%0.49833%0.329SS..  trans-65.2163.5-177.5-65.4-176.865.500112.2N86 D136 N138N86-M141 PolarHBondContact ND2-O 3.04Å; D136-M141 WeakPolarHBondContact OD2-CB 3.2Å; N138-M141 HydrophobicContact CB-CB 3.95Å; N138-M141 HydrophobicContact CB-CG 3.95Å; N138-M141 HydrophobicContact CB-SD 4.05Å; N138-M141 PolarHBondContact OD1-N 2.86Å
142S84.9Confident93.5Very high84 Ų8459 Ų5959%0.58734%0.338SS*.  trans-108.42.5-173.456.40000114.3G144 R145S142-G144 PolarHBondContact O-N 3.44Å; S142-R145 WeakPolarHBondContact O-CB 3.31Å; S142-R145 PolarHBondContact O-N 3.23Å; S142-R145 VanDerWaalsContact O-N 3.07Å
143Q94.8Very high93.6Very high113 Ų11357.9 Ų57.953%0.52833%0.333SS..THydrogen-bonded Turntrans-63132.9178.6-167.1-175.7-33.700109.8N86 E134 D136 R145N86-Q143 VanDerWaalsContact CB-O 3.25Å; N86-Q143 WeakPolarHBondContact CB-O 3.3Å; E134-Q143 WeakPolarHBondContact O-CG 3.34Å; E134-Q143 PolarHBondContact O-NE2 3.11Å; D136-Q143 HydrophobicContact CB-CB 4.13Å; D136-Q143 WeakPolarHBondContact OD2-CB 3.47Å; Q143-R145 VanDerWaalsContact C-N 3.27Å; Q143-R145 PolarHBondContact O-N 2.85Å
144G95.8Very high93.7Very high10 Ų1054.1 Ų54.110%0.10331%0.313CS..THydrogen-bonded Turntrans77.24.2-175.200000115.2G85 N86 G131 S142G85-G144 CarbonylContact C-O 3.11Å; G85-G144 WeakPolarHBondContact CA-O 3.34Å; G85-G144 PolarHBondContact N-O 3.28Å; N86-G144 PolarHBondContact N-O 3.48Å; G131-G144 CarbonylContact C-O 3.53Å; G131-G144 WeakPolarHBondContact CA-O 3.49Å; G131-G144 CarbonylContact O-C 3.6Å; G131-G144 WeakPolarHBondContact O-CA 3.32Å; S142-G144 PolarHBondContact O-N 3.44Å
145R97.8Very high93.7Very high50 Ų5055.5 Ų55.519%0.18932%0.315CS..  trans-63.9-53.8173.1-178.7-172.2168.786.9-4.4111.7H84 G85 N86 E87 N128 S142 Q143 D152H84-R145 VanDerWaalsContact CA-O 3.28Å; H84-R145 WeakPolarHBondContact CA-O 3.47Å; H84-R145 HydrophobicContact CB-CG 3.85Å; H84-R145 PolarHBondContact CE1-NH1 3.03Å; H84-R145 PolarHBondContact CE1-NH2 3.47Å; H84-R145 PolarHBondContact ND1-NH1 3.3Å; H84-R145 VanDerWaalsContact NE2-CZ 3.34Å; H84-R145 PolarHBondContact NE2-NH2 3.33Å; H84-R145 VanDerWaalsContact NE2-NH2 3.17Å; G85-R145 PolarHBondContact N-O 3.03Å; N86-R145 VanDerWaalsContact OD1-CA 3.24Å; N86-R145 WeakPolarHBondContact OD1-CA 3.27Å; N86-R145 WeakPolarHBondContact OD1-CB 3.16Å; E87-R145 IonicContact OE1-CZ 2.72Å; E87-R145 IonicContact OE1-NH1 2.91Å; E87-R145 PolarHBondContact OE1-NH1 2.79Å; N128-R145 PolarHBondContact ND2-O 2.83Å; S142-R145 WeakPolarHBondContact O-CB 3.31Å; S142-R145 PolarHBondContact O-N 3.23Å; S142-R145 VanDerWaalsContact O-N 3.07Å; Q143-R145 VanDerWaalsContact C-N 3.27Å; Q143-R145 PolarHBondContact O-N 2.85Å; R145-D152 IonicContact CZ-OD2 3.96Å; R145-D152 VanDerWaalsContact CZ-OD2 3.32Å; R145-D152 IonicContact NE-OD2 2.79Å; R145-D152 PolarHBondContact NE-OD2 3.35Å; R145-D152 IonicContact NH2-OD2 2.71Å; R145-D152 PolarHBondContact NH2-OD2 3.42Å
146A97.8Very high93.5Very high28 Ų2855.1 Ų55.123%0.23131%0.313CS..SBendtrans-70.7166.4-179.100000111.5N128 G131 G150 V151N128-A146 VanDerWaalsContact ND2-C 3.27Å; N128-A146 PolarHBondContact ND2-O 2.96Å; G131-A146 WeakPolarHBondContact CA-O 3.46Å; A146-G150 VanDerWaalsContact CB-C 3.49Å; A146-V151 CarbonylContact C-O 3.49Å; A146-V151 WeakPolarHBondContact CA-O 3.48Å; A146-V151 WeakPolarHBondContact CB-O 3.43Å
147N97.8Very high93.8Very high3 Ų354.2 Ų54.22%0.01631%0.308CS..  trans-73.8-178.2167.782.8-19.8000111.2N128 N149 G150 V151 L153 E176 E178N128-N147 PolarHBondContact ND2-N 3.13Å; N128-N147 WeakPolarHBondContact OD1-CA 3.31Å; N147-N149 PolarHBondContact O-N 2.86Å; N147-N149 VanDerWaalsContact O-N 3.14Å; N147-N149 PolarHBondContact OD1-N 3.06Å; N147-G150 PolarHBondContact O-N 3.09Å; N147-V151 PolarHBondContact N-O 2.88Å; N147-V151 WeakPolarHBondContact OD1-CB 3.5Å; N147-V151 PolarHBondContact OD1-N 3.2Å; N147-V151 PolarHBondContact OD1-O 2.84Å; N147-L153 HydrophobicContact CB-CD1 4.31Å; N147-L153 HydrophobicContact CB-CD2 3.79Å; N147-L153 HydrophobicContact CB-CG 4.06Å; N147-E176 WeakPolarHBondContact ND2-CG 3.39Å; N147-E176 PolarHBondContact ND2-OE2 3.29Å; N147-E178 PolarHBondContact ND2-OE2 3.26Å; N147-E178 VanDerWaalsContact ND2-OE2 3.08Å
148H97.2Very high93.8Very high74 Ų7449.5 Ų49.534%0.34328%0.279SS..THydrogen-bonded Turntrans-56.8-32.1-177.1-174.156.4000114.6V52 K53 D130 E134 G150V52-H148 HydrophobicContact CB-CB 4.1Å; V52-H148 HydrophobicContact CG1-CB 4.33Å; K53-H148 HydrophobicContact CB-CB 3.96Å; K53-H148 WeakPolarHBondContact CD-ND1 3.49Å; D130-H148 HydrophobicContact CB-CB 3.99Å; E134-H148 IonicContact OE1-CE1 2.86Å; E134-H148 IonicContact OE1-ND1 3.82Å; E134-H148 PolarHBondContact OE1-ND1 2.74Å; H148-G150 PolarHBondContact O-N 2.64Å
149N96.8Very high93.9Very high94 Ų9446.9 Ų46.950%0.50327%0.265SS..THydrogen-bonded Turntrans-81.24.5177.9-71.2-27.6000113.2N147 V151 E176N147-N149 PolarHBondContact O-N 2.86Å; N147-N149 VanDerWaalsContact O-N 3.14Å; N147-N149 PolarHBondContact OD1-N 3.06Å; N149-V151 VanDerWaalsContact C-N 3.33Å; N149-V151 HydrophobicContact CB-CG2 4.34Å; N149-E176 PolarHBondContact ND2-OE2 3.16Å
150G96.4Very high93.8Very high58 Ų5845.6 Ų45.660%0.59826%0.258SS*.SBendtrans76.417.8-177.100000113.9A146 N147 H148A146-G150 VanDerWaalsContact CB-C 3.49Å; N147-G150 PolarHBondContact O-N 3.09Å; H148-G150 PolarHBondContact O-N 2.64Å
151V96.7Very high93.7Very high48 Ų4840.6 Ų40.629%0.29123%0.231SC..  trans-93.6132.41791790000110.9A146 N147 N149 L153 E176A146-V151 CarbonylContact C-O 3.49Å; A146-V151 WeakPolarHBondContact CA-O 3.48Å; A146-V151 WeakPolarHBondContact CB-O 3.43Å; N147-V151 PolarHBondContact N-O 2.88Å; N147-V151 WeakPolarHBondContact OD1-CB 3.5Å; N147-V151 PolarHBondContact OD1-N 3.2Å; N147-V151 PolarHBondContact OD1-O 2.84Å; N149-V151 VanDerWaalsContact C-N 3.33Å; N149-V151 HydrophobicContact CB-CG2 4.34Å; V151-L153 PolarHBondContact O-N 3.23Å; V151-E176 HydrophobicContact CB-CG 3.75Å; V151-E176 HydrophobicContact CG1-CG 3.73Å; V151-E176 HydrophobicContact CG2-CG 3.98Å
152D97.6Very high93.1Very high35 Ų3536.2 Ų36.219%0.18721%0.212CC..  trans-73.1109.2168-173.2-42.8000109H84 R145 N154 R155 G156H84-D152 IonicContact CD2-OD1 2.81Å; H84-D152 IonicContact NE2-OD1 2.94Å; H84-D152 PolarHBondContact NE2-OD1 3.01Å; H84-D152 VanDerWaalsContact NE2-OD1 3.11Å; H84-D152 IonicContact NE2-OD2 3.46Å; R145-D152 IonicContact CZ-OD2 3.96Å; R145-D152 VanDerWaalsContact CZ-OD2 3.32Å; R145-D152 IonicContact NE-OD2 2.79Å; R145-D152 PolarHBondContact NE-OD2 3.35Å; R145-D152 IonicContact NH2-OD2 2.71Å; R145-D152 PolarHBondContact NH2-OD2 3.42Å; D152-N154 PolarHBondContact O-N 2.89Å; D152-N154 WeakPolarHBondContact OD1-CA 3.27Å; D152-N154 PolarHBondContact OD1-N 3.27Å; D152-R155 HydrophobicContact CB-CB 4.3Å; D152-R155 HydrophobicContact CB-CG 4.04Å; D152-R155 PolarHBondContact O-N 2.97Å; D152-R155 PolarHBondContact OD1-N 3.42Å; D152-G156 PolarHBondContact O-N 3.13Å
153L98.3Very high91.8Very high0 Ų033.3 Ų33.30%019%0.194CC..G310 helixtrans-61.8-28.2-177.4-61.5-175.1000112.4M83 M127 N128 N147 V151 R155 G156 F157 E176 E178 V179M83-L153 HydrophobicContact CE-CB 4.09Å; M127-L153 HydrophobicContact CE-CB 4.34Å; M127-L153 HydrophobicContact CE-CD1 4.16Å; M127-L153 HydrophobicContact CG-CD1 4.31Å; N128-L153 HydrophobicContact CB-CD1 3.71Å; N147-L153 HydrophobicContact CB-CD1 4.31Å; N147-L153 HydrophobicContact CB-CD2 3.79Å; N147-L153 HydrophobicContact CB-CG 4.06Å; V151-L153 PolarHBondContact O-N 3.23Å; L153-R155 PolarHBondContact O-N 3.27Å; L153-G156 PolarHBondContact O-N 3.32Å; L153-G156 VanDerWaalsContact O-N 3.11Å; L153-F157 WeakPolarHBondContact O-CD2 3.29Å; L153-E176 HydrophobicContact CD2-CB 3.92Å; L153-E176 HydrophobicContact CD2-CG 4.24Å; L153-E178 HydrophobicContact CD1-CB 3.78Å; L153-E178 HydrophobicContact CD1-CG 4.08Å; L153-E178 HydrophobicContact CD2-CB 4.21Å; L153-V179 HydrophobicContact CD2-CG2 4.04Å
154N98.3Very high90Very high3 Ų333.6 Ų33.62%0.01620%0.199CC..G310 helixtrans-86.515.5176.4-15421.8000112.9M83 D152 G271 G272 M273M83-N154 VanDerWaalsContact CE-CA 3.49Å; M83-N154 HydrophobicContact CE-CB 3.39Å; M83-N154 HydrophobicContact SD-CB 3.78Å; D152-N154 PolarHBondContact O-N 2.89Å; D152-N154 WeakPolarHBondContact OD1-CA 3.27Å; D152-N154 PolarHBondContact OD1-N 3.27Å; N154-G271 CarbonylContact C-O 3.49Å; N154-G272 VanDerWaalsContact OD1-CA 3.31Å; N154-G272 WeakPolarHBondContact OD1-CA 3.37Å; N154-M273 PolarHBondContact OD1-N 3.32Å
155R95.8Very high88Confident92 Ų9239.3 Ų39.335%0.34722%0.218SC..G310 helixtrans-122.56.2161.2-56.7-64.5-179.4-78.9-0.2111.1D152 L153 L269 E270 G271D152-R155 HydrophobicContact CB-CB 4.3Å; D152-R155 HydrophobicContact CB-CG 4.04Å; D152-R155 PolarHBondContact O-N 2.97Å; D152-R155 PolarHBondContact OD1-N 3.42Å; L153-R155 PolarHBondContact O-N 3.27Å; R155-L269 VanDerWaalsContact CZ-CG 3.4Å; R155-L269 VanDerWaalsContact NH1-CG 3.29Å; R155-E270 WeakPolarHBondContact CD-O 3.21Å; R155-G271 CarbonylContact C-O 3.54Å; R155-G271 WeakPolarHBondContact CA-O 3.44Å
156G92.9Very high85.8Confident12 Ų1242.7 Ų42.712%0.12423%0.234CC..SBendtrans-95.2-7.2-169.700000114.5D152 L153 R175 G271D152-G156 PolarHBondContact O-N 3.13Å; L153-G156 PolarHBondContact O-N 3.32Å; L153-G156 VanDerWaalsContact O-N 3.11Å; G156-R175 WeakPolarHBondContact O-CD 3.17Å; G156-R175 PolarHBondContact O-NH1 3.09Å; G156-G271 PolarHBondContact N-O 2.71Å
157F94.8Very high83.4Confident4 Ų450.1 Ų50.12%0.01826%0.263CS..SBendtrans-88.6158.4-178.1-73.4-100.5000112.9M83 M127 L153 R175 V179 V182 I183 G271 M273 Y276M83-F157 HydrophobicContact CE-CE2 4.35Å; M127-F157 HydrophobicContact CE-CE2 3.94Å; M127-F157 HydrophobicContact CE-CZ 3.85Å; L153-F157 WeakPolarHBondContact O-CD2 3.29Å; F157-R175 PolarHBondContact O-NH1 3.1Å; F157-V179 HydrophobicContact CD1-CG1 3.99Å; F157-V179 HydrophobicContact CD2-CG1 4.12Å; F157-V179 HydrophobicContact CD2-CG2 4.38Å; F157-V179 HydrophobicContact CE1-CG1 3.97Å; F157-V179 HydrophobicContact CE2-CG1 4.08Å; F157-V179 HydrophobicContact CE2-CG2 4.05Å; F157-V179 HydrophobicContact CG-CG1 4.06Å; F157-V179 HydrophobicContact CZ-CG1 4.02Å; F157-V179 HydrophobicContact CZ-CG2 4.49Å; F157-V182 HydrophobicContact CE1-CB 4.42Å; F157-V182 HydrophobicContact CE1-CG1 4.07Å; F157-V182 HydrophobicContact CZ-CB 4.17Å; F157-V182 HydrophobicContact CZ-CG1 3.98Å; F157-I183 HydrophobicContact CD1-CD1 4.23Å; F157-I183 HydrophobicContact CD1-CG1 4.05Å; F157-I183 HydrophobicContact CE1-CD1 4.49Å; F157-I183 HydrophobicContact CE1-CG1 3.92Å; F157-G271 WeakPolarHBondContact CB-O 3.21Å; F157-G271 PolarHBondContact N-O 3.29Å; F157-G271 VanDerWaalsContact O-CA 3.27Å; F157-G271 WeakPolarHBondContact O-CA 3.3Å; F157-M273 HydrophobicContact CD1-CG 4.47Å; F157-M273 HydrophobicContact CD2-CB 3.8Å; F157-M273 HydrophobicContact CD2-CG 4.39Å; F157-M273 HydrophobicContact CE1-CB 4.32Å; F157-M273 HydrophobicContact CE1-CG 3.87Å; F157-M273 HydrophobicContact CE1-SD 4.43Å; F157-M273 HydrophobicContact CE2-CB 3.53Å; F157-M273 HydrophobicContact CE2-CG 3.8Å; F157-M273 HydrophobicContact CE2-SD 4.09Å; F157-M273 HydrophobicContact CG-CB 4.32Å; F157-M273 HydrophobicContact CZ-CB 3.81Å; F157-M273 HydrophobicContact CZ-CG 3.5Å; F157-M273 VanDerWaalsContact CZ-CG 3.5Å; F157-M273 HydrophobicContact CZ-SD 3.65Å; F157-Y276 HydrophobicContact CB-CG 4.38Å; F157-Y276 AromaticContact CD1-CD1 3.87Å; F157-Y276 HydrophobicContact CD1-CD1 3.87Å; F157-Y276 HydrophobicContact CD1-CD2 4.34Å; F157-Y276 AromaticContact CD1-CG 3.76Å; F157-Y276 HydrophobicContact CD1-CG 3.76Å; F157-Y276 HydrophobicContact CE1-CD1 4.31Å; F157-Y276 HydrophobicContact CG-CG 4.49Å
158P91.6Very high81.1Confident2 Ų255.5 Ų55.51%0.01329%0.289CS..  trans-56138.9168.7-22.932000111.4L170 E172 R175 I183 Y276 W280P158-L170 HydrophobicContact CB-CD2 3.67Å; P158-E172 HydrophobicContact CG-CG 4.07Å; P158-R175 VanDerWaalsContact CA-NH2 3.29Å; P158-R175 VanDerWaalsContact CG-CZ 3.43Å; P158-R175 VanDerWaalsContact CG-NH2 3.34Å; P158-R175 VanDerWaalsContact N-NH1 3.17Å; P158-I183 HydrophobicContact CG-CD1 4.36Å; P158-Y276 HydrophobicContact CB-CD2 3.91Å; P158-Y276 HydrophobicContact CB-CE2 3.94Å; P158-Y276 HydrophobicContact CG-CD2 3.77Å; P158-Y276 HydrophobicContact CG-CE2 3.48Å; P158-Y276 VanDerWaalsContact CG-CE2 3.48Å; P158-W280 HydrophobicContact CB-CH2 3.94Å; P158-W280 HydrophobicContact CB-CZ2 4.36Å; P158-W280 HydrophobicContact CB-CZ3 4.15Å; P158-W280 WeakPolarHBondContact O-CH2 3.5Å; P158-W280 WeakPolarHBondContact O-CZ3 3.26Å
159D89.4Confident78.9Confident12 Ų1259.7 Ų59.76%0.06431%0.308CS..  trans-118126.4-176.6-174.4-78000111.3F161 A162 G163 N210 E270 G271D159-F161 VanDerWaalsContact C-N 3.26Å; D159-F161 PolarHBondContact O-N 3.11Å; D159-F161 WeakPolarHBondContact OD1-CA 3.49Å; D159-F161 WeakPolarHBondContact OD1-CB 3.26Å; D159-F161 PolarHBondContact OD1-N 2.98Å; D159-A162 HydrophobicContact CB-CB 3.81Å; D159-A162 WeakPolarHBondContact OD1-CB 3.41Å; D159-A162 PolarHBondContact OD1-N 3.25Å; D159-G163 PolarHBondContact O-N 3.08Å; D159-N210 VanDerWaalsContact CG-ND2 3.25Å; D159-N210 PolarHBondContact OD1-ND2 2.93Å; D159-N210 PolarHBondContact OD2-ND2 3.2Å; D159-E270 HydrophobicContact CB-CG 4.14Å; D159-E270 WeakPolarHBondContact OD2-CA 3.44Å; D159-G271 PolarHBondContact OD2-N 3.29Å
160A86.1Confident77.3Confident20 Ų2057 Ų5717%0.16529%0.294CS..THydrogen-bonded Turntrans-73.2-20.7-171.400000112.7V279 W280 M348A160-V279 HydrophobicContact CB-CG1 4.13Å; A160-V279 HydrophobicContact CB-CG2 4.07Å; A160-W280 HydrophobicContact CB-CH2 3.82Å; A160-W280 HydrophobicContact CB-CZ2 4.3Å; A160-W280 HydrophobicContact CB-CZ3 4.37Å; A160-M348 HydrophobicContact CB-SD 3.7Å
161F83.8Confident76.2Confident9 Ų956.6 Ų56.64%0.03928%0.278CS..THydrogen-bonded Turntrans-101-30.5-176.1-55-88.2000111.9D159 L164 Y208 N210 D212 M348D159-F161 VanDerWaalsContact C-N 3.26Å; D159-F161 PolarHBondContact O-N 3.11Å; D159-F161 WeakPolarHBondContact OD1-CA 3.49Å; D159-F161 WeakPolarHBondContact OD1-CB 3.26Å; D159-F161 PolarHBondContact OD1-N 2.98Å; F161-L164 WeakPolarHBondContact O-CB 3.3Å; F161-L164 PolarHBondContact O-N 3.19Å; F161-Y208 AromaticContact CE2-CD1 3.93Å; F161-Y208 HydrophobicContact CE2-CD1 3.93Å; F161-Y208 HydrophobicContact CE2-CE1 4.48Å; F161-Y208 AromaticContact CE2-CG 3.99Å; F161-Y208 HydrophobicContact CE2-CG 3.99Å; F161-Y208 AromaticContact CZ-CD1 3.93Å; F161-Y208 HydrophobicContact CZ-CD1 3.93Å; F161-Y208 AromaticContact CZ-CD2 3.87Å; F161-Y208 HydrophobicContact CZ-CD2 3.87Å; F161-Y208 HydrophobicContact CZ-CE1 4.33Å; F161-Y208 HydrophobicContact CZ-CE2 4.24Å; F161-Y208 AromaticContact CZ-CG 3.68Å; F161-Y208 HydrophobicContact CZ-CG 3.68Å; F161-N210 HydrophobicContact CB-CB 4.5Å; F161-N210 HydrophobicContact CD2-CB 3.62Å; F161-N210 HydrophobicContact CE2-CB 4.1Å; F161-N210 WeakPolarHBondContact CE2-O 3.36Å; F161-N210 HydrophobicContact CG-CB 4.3Å; F161-N210 WeakPolarHBondContact CZ-O 3.32Å; F161-D212 HydrophobicContact CD1-CB 4.03Å; F161-D212 VanDerWaalsContact CD1-N 3.29Å; F161-M348 HydrophobicContact CD1-CE 4.06Å; F161-M348 HydrophobicContact CE1-CE 3.3Å; F161-M348 HydrophobicContact CE2-CE 4.12Å; F161-M348 HydrophobicContact CZ-CE 3.35Å
162A71.2Confident75.5Confident10 Ų1055.3 Ų55.38%0.08327%0.269CS..THydrogen-bonded Turntrans-69.2-38.9175.600000111.7D159 L164 R165 K166 E270D159-A162 HydrophobicContact CB-CB 3.81Å; D159-A162 WeakPolarHBondContact OD1-CB 3.41Å; D159-A162 PolarHBondContact OD1-N 3.25Å; A162-L164 PolarHBondContact O-N 3Å; A162-R165 PolarHBondContact O-N 3.35Å; A162-K166 PolarHBondContact O-N 3.02Å; A162-E270 HydrophobicContact CB-CG 4.03Å; A162-E270 WeakPolarHBondContact CB-OE1 3.42Å
163G56.6Low74.7Confident22 Ų2261.3 Ų61.323%0.22730%0.295CS..THydrogen-bonded Turntrans-61.8-21.2175.300000114D159 R165D159-G163 PolarHBondContact O-N 3.08Å; G163-R165 VanDerWaalsContact C-N 3.31Å
164L57Low74Confident119 Ų11968.6 Ų68.662%0.62333%0.33SS*.THydrogen-bonded Turntrans-75.2-20172.3-61.5173.2000112.8F161 A162 D212F161-L164 WeakPolarHBondContact O-CB 3.3Å; F161-L164 PolarHBondContact O-N 3.19Å; A162-L164 PolarHBondContact O-N 3Å; L164-D212 HydrophobicContact CD1-CB 4.1Å
165R54.5Low73.7Confident131 Ų13170.8 Ų70.849%0.49434%0.338SS..THydrogen-bonded Turntrans-111-33.5-173.2-65.2-176.7178.5178.94113.5A162 G163 D212 Q213A162-R165 PolarHBondContact O-N 3.35Å; G163-R165 VanDerWaalsContact C-N 3.31Å; R165-D212 PolarHBondContact NH2-O 2.79Å; R165-Q213 PolarHBondContact NH2-O 3.18Å
166K51.7Low73.7Confident120 Ų12068.1 Ų68.152%0.52233%0.329SS..SBendtrans-119.8131176.4-66.8173.3-178.5168.90106.6A162 Q168A162-K166 PolarHBondContact O-N 3.02Å; K166-Q168 HydrophobicContact CB-CB 3.98Å; K166-Q168 PolarHBondContact O-N 3.23Å
167Q47.1Very low74Confident184 Ų18468.5 Ų68.586%0.8633%0.331SS*.  trans-65.952.4160.6-75.2164.9-59.100109.5E169Q167-E169 PolarHBondContact O-N 3.08Å
168Q48.7Very low74.1Confident117 Ų11768.3 Ų68.355%0.54733%0.33SS..  trans-81.1109.5175.4-160.7160.4-300104.4K166 L170K166-Q168 HydrophobicContact CB-CB 3.98Å; K166-Q168 PolarHBondContact O-N 3.23Å; Q168-L170 PolarHBondContact O-N 2.8Å
169E52.6Low74.5Confident161 Ų16168.2 Ų68.275%0.75233%0.33SS*.  trans-52.2120.6171.4-68.5-176.1160.500107.1Q167 N171Q167-E169 PolarHBondContact O-N 3.08Å; E169-N171 HydrophobicContact CB-CB 4.37Å; E169-N171 PolarHBondContact O-N 3.47Å
170L61.9Low74.8Confident38 Ų3873.2 Ų73.220%0.19935%0.348CS..  trans-68.836.7176.2-65.6156.4000110.1P158 Q168 E172 Y422P158-L170 HydrophobicContact CB-CD2 3.67Å; Q168-L170 PolarHBondContact O-N 2.8Å; L170-E172 PolarHBondContact O-N 3.17Å; L170-Y422 HydrophobicContact CB-CD1 3.69Å; L170-Y422 HydrophobicContact CB-CE1 4.43Å; L170-Y422 HydrophobicContact CD1-CD1 3.83Å; L170-Y422 HydrophobicContact CD1-CG 4.49Å; L170-Y422 HydrophobicContact CG-CD1 4.37Å
171N73.3Confident75.4Confident49 Ų4972.7 Ų72.726%0.26234%0.344SS..  trans-67.3101.5-170.7-169.6-8.5000109.5E169 E173 Q174E169-N171 HydrophobicContact CB-CB 4.37Å; E169-N171 PolarHBondContact O-N 3.47Å; N171-E173 PolarHBondContact O-N 3.23Å; N171-E173 WeakPolarHBondContact OD1-CB 3.14Å; N171-E173 PolarHBondContact OD1-N 3.25Å; N171-E173 VanDerWaalsContact OD1-N 3.08Å; N171-Q174 PolarHBondContact O-N 3.22Å
172E82.1Confident76.1Confident22 Ų2272.3 Ų72.310%0.10334%0.342CS..G310 helixtrans-67.5-25.8-179.8-64.1175.2168.300111.9P158 L170 Q174 R175 R180 I183 R187 Y276 Y422P158-E172 HydrophobicContact CG-CG 4.07Å; L170-E172 PolarHBondContact O-N 3.17Å; E172-Q174 PolarHBondContact O-N 2.94Å; E172-R175 WeakPolarHBondContact O-CB 3.38Å; E172-R175 PolarHBondContact O-N 3.19Å; E172-R180 WeakPolarHBondContact O-CD 3.45Å; E172-R180 WeakPolarHBondContact O-CG 3.47Å; E172-I183 HydrophobicContact CB-CD1 4.33Å; E172-I183 HydrophobicContact CG-CD1 3.97Å; E172-I183 HydrophobicContact CG-CG2 4.5Å; E172-I183 WeakPolarHBondContact OE2-CG2 3.37Å; E172-R187 VanDerWaalsContact CD-NH2 3.27Å; E172-R187 IonicContact OE1-NH2 2.67Å; E172-R187 PolarHBondContact OE1-NH2 3.44Å; E172-R187 IonicContact OE2-CZ 3.95Å; E172-R187 IonicContact OE2-NH1 3.83Å; E172-R187 PolarHBondContact OE2-NH1 2.81Å; E172-R187 IonicContact OE2-NH2 3.05Å; E172-R187 PolarHBondContact OE2-NH2 3.13Å; E172-Y276 PolarHBondContact OE1-OH 3.33Å; E172-Y422 PolarHBondContact OE1-OH 3.28Å
173E80.6Confident77.3Confident160 Ų16071.9 Ų71.975%0.74834%0.338SS*.G310 helixtrans-66.6-25.5-178.3-59.8-173.9164.700113N171 R175 R180N171-E173 PolarHBondContact O-N 3.23Å; N171-E173 WeakPolarHBondContact OD1-CB 3.14Å; N171-E173 PolarHBondContact OD1-N 3.25Å; N171-E173 VanDerWaalsContact OD1-N 3.08Å; E173-R175 VanDerWaalsContact C-N 3.33Å; E173-R180 WeakPolarHBondContact O-CD 3.4Å
174Q85.2Confident79.3Confident154 Ų15472.7 Ų72.772%0.7235%0.346SS*.G310 helixtrans-87.70.3179.6-67.3179.9-16.300113.5N171 E172N171-Q174 PolarHBondContact O-N 3.22Å; E172-Q174 PolarHBondContact O-N 2.94Å
175R91.3Very high81.3Confident48 Ų4867.2 Ų67.218%0.18132%0.317CS..SBendtrans-82.2161.8-179-59.9177.6-174.2-81.3-5.5111.5G156 F157 P158 E172 E173 V179 R180G156-R175 WeakPolarHBondContact O-CD 3.17Å; G156-R175 PolarHBondContact O-NH1 3.09Å; F157-R175 PolarHBondContact O-NH1 3.1Å; P158-R175 VanDerWaalsContact CA-NH2 3.29Å; P158-R175 VanDerWaalsContact CG-CZ 3.43Å; P158-R175 VanDerWaalsContact CG-NH2 3.34Å; P158-R175 VanDerWaalsContact N-NH1 3.17Å; E172-R175 WeakPolarHBondContact O-CB 3.38Å; E172-R175 PolarHBondContact O-N 3.19Å; E173-R175 VanDerWaalsContact C-N 3.33Å; R175-V179 HydrophobicContact CB-CB 4.15Å; R175-V179 HydrophobicContact CB-CG1 3.99Å; R175-V179 HydrophobicContact CG-CG1 4.48Å; R175-R180 HydrophobicContact CB-CG 4.06Å; R175-R180 WeakPolarHBondContact O-CD 3.38Å; R175-R180 PolarHBondContact O-NE 3.04Å
176E96.4Very high83.3Confident37 Ų3761.5 Ų61.517%0.17330%0.296CS..  trans-53.4150.7175.9-67.5-56120.100111.9N147 N149 V151 L153 E178 V179 R180N147-E176 WeakPolarHBondContact ND2-CG 3.39Å; N147-E176 PolarHBondContact ND2-OE2 3.29Å; N149-E176 PolarHBondContact ND2-OE2 3.16Å; V151-E176 HydrophobicContact CB-CG 3.75Å; V151-E176 HydrophobicContact CG1-CG 3.73Å; V151-E176 HydrophobicContact CG2-CG 3.98Å; L153-E176 HydrophobicContact CD2-CB 3.92Å; L153-E176 HydrophobicContact CD2-CG 4.24Å; E176-E178 PolarHBondContact O-N 2.98Å; E176-V179 HydrophobicContact CB-CG2 4.26Å; E176-V179 PolarHBondContact O-N 3.25Å; E176-V179 VanDerWaalsContact O-N 3.09Å; E176-R180 PolarHBondContact O-N 2.98Å
177A97.5Very high85.4Confident20 Ų2062.7 Ų62.717%0.16530%0.298CS..Hα-helixtrans-57.9-39.3-173.200000112K50 V52 R180 A181K50-A177 WeakPolarHBondContact O-CB 3.45Å; V52-A177 HydrophobicContact CG2-CB 4.03Å; A177-R180 PolarHBondContact O-N 3.36Å; A177-A181 WeakPolarHBondContact O-CB 3.39Å; A177-A181 PolarHBondContact O-N 3.37Å
178E98.6Very high87.7Confident0 Ų057.4 Ų57.40%028%0.281CS..Hα-helixtrans-66.3-43177.8-57.580.3-17500111.6S51 V52 L58 M127 N147 L153 E176 A181 V182S51-E178 VanDerWaalsContact CA-OE1 3.27Å; S51-E178 WeakPolarHBondContact CA-OE1 3.48Å; S51-E178 WeakPolarHBondContact CB-OE1 3.19Å; V52-E178 PolarHBondContact N-OE1 3.39Å; V52-E178 VanDerWaalsContact N-OE1 3.13Å; L58-E178 HydrophobicContact CD2-CB 4.12Å; L58-E178 HydrophobicContact CD2-CG 4.26Å; M127-E178 HydrophobicContact CE-CB 4.28Å; M127-E178 HydrophobicContact CG-CB 4.44Å; M127-E178 WeakPolarHBondContact O-CG 3.43Å; N147-E178 PolarHBondContact ND2-OE2 3.26Å; N147-E178 VanDerWaalsContact ND2-OE2 3.08Å; L153-E178 HydrophobicContact CD1-CB 3.78Å; L153-E178 HydrophobicContact CD1-CG 4.08Å; L153-E178 HydrophobicContact CD2-CB 4.21Å; E176-E178 PolarHBondContact O-N 2.98Å; E178-A181 WeakPolarHBondContact O-CB 3.49Å; E178-A181 PolarHBondContact O-N 3.24Å; E178-V182 WeakPolarHBondContact O-CG2 3.33Å; E178-V182 PolarHBondContact O-N 3.33Å
179V98.1Very high89.9Confident0 Ų053.7 Ų53.70%026%0.264CS..Hα-helixtrans-63.8-45.8176.7176.50000110.4M127 L153 F157 R175 E176 A181 V182 I183M127-V179 HydrophobicContact CE-CG2 4.43Å; L153-V179 HydrophobicContact CD2-CG2 4.04Å; F157-V179 HydrophobicContact CD1-CG1 3.99Å; F157-V179 HydrophobicContact CD2-CG1 4.12Å; F157-V179 HydrophobicContact CD2-CG2 4.38Å; F157-V179 HydrophobicContact CE1-CG1 3.97Å; F157-V179 HydrophobicContact CE2-CG1 4.08Å; F157-V179 HydrophobicContact CE2-CG2 4.05Å; F157-V179 HydrophobicContact CG-CG1 4.06Å; F157-V179 HydrophobicContact CZ-CG1 4.02Å; F157-V179 HydrophobicContact CZ-CG2 4.49Å; R175-V179 HydrophobicContact CB-CB 4.15Å; R175-V179 HydrophobicContact CB-CG1 3.99Å; R175-V179 HydrophobicContact CG-CG1 4.48Å; E176-V179 HydrophobicContact CB-CG2 4.26Å; E176-V179 PolarHBondContact O-N 3.25Å; E176-V179 VanDerWaalsContact O-N 3.09Å; V179-A181 VanDerWaalsContact C-N 3.32Å; V179-A181 PolarHBondContact O-N 3.2Å; V179-V182 PolarHBondContact O-N 3.32Å; V179-I183 HydrophobicContact CG1-CD1 3.8Å; V179-I183 HydrophobicContact CG1-CG1 4.34Å; V179-I183 WeakPolarHBondContact O-CB 3.32Å; V179-I183 WeakPolarHBondContact O-CG1 3.46Å; V179-I183 PolarHBondContact O-N 2.93Å
180R97.1Very high92Very high116 Ų11647.9 Ų47.944%0.43824%0.239SC..Hα-helixtrans-62.1-40.4177.2-72.6-172.9-66.6114.40.4112.3E172 E173 R175 E176 A177 I183 G184E172-R180 WeakPolarHBondContact O-CD 3.45Å; E172-R180 WeakPolarHBondContact O-CG 3.47Å; E173-R180 WeakPolarHBondContact O-CD 3.4Å; R175-R180 HydrophobicContact CB-CG 4.06Å; R175-R180 WeakPolarHBondContact O-CD 3.38Å; R175-R180 PolarHBondContact O-NE 3.04Å; E176-R180 PolarHBondContact O-N 2.98Å; A177-R180 PolarHBondContact O-N 3.36Å; R180-I183 PolarHBondContact O-N 3.4Å; R180-G184 PolarHBondContact O-N 3.41Å
181A98.3Very high93.8Very high10 Ų1046.3 Ų46.38%0.08323%0.231CC..Hα-helixtrans-60.1-46.9175.800000111.3I48 L58 A177 E178 V179 G184 W185I48-A181 HydrophobicContact CD1-CB 4.41Å; I48-A181 HydrophobicContact CG1-CB 4.29Å; I48-A181 WeakPolarHBondContact O-CB 3.42Å; L58-A181 HydrophobicContact CD2-CB 3.95Å; A177-A181 WeakPolarHBondContact O-CB 3.39Å; A177-A181 PolarHBondContact O-N 3.37Å; E178-A181 WeakPolarHBondContact O-CB 3.49Å; E178-A181 PolarHBondContact O-N 3.24Å; V179-A181 VanDerWaalsContact C-N 3.32Å; V179-A181 PolarHBondContact O-N 3.2Å; A181-G184 PolarHBondContact O-N 3.36Å; A181-W185 VanDerWaalsContact O-CB 3.3Å; A181-W185 WeakPolarHBondContact O-CB 3.26Å; A181-W185 PolarHBondContact O-N 2.94Å
182V98.7Very high95Very high0 Ų044.3 Ų44.30%022%0.22CC..Hα-helixtrans-66.8-41.8177.71730000112I48 L124 M127 F157 E178 V179 G184 W185 L186 M273I48-V182 HydrophobicContact CD1-CG2 4.01Å; L124-V182 HydrophobicContact CD2-CG2 4.34Å; M127-V182 HydrophobicContact CE-CB 4.27Å; M127-V182 HydrophobicContact CE-CG2 3.7Å; M127-V182 HydrophobicContact CG-CG2 4.14Å; M127-V182 HydrophobicContact SD-CG2 3.87Å; F157-V182 HydrophobicContact CE1-CB 4.42Å; F157-V182 HydrophobicContact CE1-CG1 4.07Å; F157-V182 HydrophobicContact CZ-CB 4.17Å; F157-V182 HydrophobicContact CZ-CG1 3.98Å; E178-V182 WeakPolarHBondContact O-CG2 3.33Å; E178-V182 PolarHBondContact O-N 3.33Å; V179-V182 PolarHBondContact O-N 3.32Å; V182-G184 PolarHBondContact O-N 2.93Å; V182-W185 WeakPolarHBondContact O-CB 3.22Å; V182-W185 PolarHBondContact O-N 3.4Å; V182-L186 HydrophobicContact CG1-CD1 4.11Å; V182-L186 HydrophobicContact CG1-CG 4.35Å; V182-L186 WeakPolarHBondContact O-CB 3.34Å; V182-L186 VanDerWaalsContact O-CG 3.31Å; V182-L186 WeakPolarHBondContact O-CG 3.49Å; V182-L186 PolarHBondContact O-N 2.91Å; V182-M273 HydrophobicContact CG1-SD 3.85Å
183I97.1Very high95.8Very high2 Ų243.2 Ų43.21%0.0122%0.215CC..Hα-helixtrans-60.2-46174.8-72.7175.6000111.3F157 P158 E172 V179 R180 W185 L186 R187 Y276F157-I183 HydrophobicContact CD1-CD1 4.23Å; F157-I183 HydrophobicContact CD1-CG1 4.05Å; F157-I183 HydrophobicContact CE1-CD1 4.49Å; F157-I183 HydrophobicContact CE1-CG1 3.92Å; P158-I183 HydrophobicContact CG-CD1 4.36Å; E172-I183 HydrophobicContact CB-CD1 4.33Å; E172-I183 HydrophobicContact CG-CD1 3.97Å; E172-I183 HydrophobicContact CG-CG2 4.5Å; E172-I183 WeakPolarHBondContact OE2-CG2 3.37Å; V179-I183 HydrophobicContact CG1-CD1 3.8Å; V179-I183 HydrophobicContact CG1-CG1 4.34Å; V179-I183 WeakPolarHBondContact O-CB 3.32Å; V179-I183 WeakPolarHBondContact O-CG1 3.46Å; V179-I183 PolarHBondContact O-N 2.93Å; R180-I183 PolarHBondContact O-N 3.4Å; I183-W185 VanDerWaalsContact C-N 3.29Å; I183-W185 PolarHBondContact O-N 3.49Å; I183-L186 PolarHBondContact O-N 3.39Å; I183-R187 PolarHBondContact O-N 2.96Å; I183-Y276 HydrophobicContact CD1-CE2 4.44Å; I183-Y276 HydrophobicContact CG1-CE1 3.8Å; I183-Y276 WeakPolarHBondContact CG2-OH 3.1Å
184G97.4Very high96.7Very high38 Ų3835.6 Ų35.639%0.39218%0.18SC..Hα-helixtrans-61.2-40.3175.500000112R180 A181 V182 R187 S188R180-G184 PolarHBondContact O-N 3.41Å; A181-G184 PolarHBondContact O-N 3.36Å; V182-G184 PolarHBondContact O-N 2.93Å; G184-R187 PolarHBondContact O-N 3.18Å; G184-S188 PolarHBondContact O-N 3.32Å
185W98.4Very high97.3Very high5 Ų528.3 Ų28.32%0.01915%0.145CC..Hα-helixtrans-65.2-42.9176.8179.240.3000112.9Y46 I48 V60 K78 V80 H122 L124 A181 V182 I183 R187 S188 F191Y46-W185 AromaticContact CZ-NE1 3.97Å; Y46-W185 PolarHBondContact OH-NE1 3.23Å; I48-W185 HydrophobicContact CB-CB 4.03Å; I48-W185 HydrophobicContact CB-CG 4.26Å; I48-W185 HydrophobicContact CD1-CB 4.15Å; I48-W185 HydrophobicContact CD1-CD2 4.17Å; I48-W185 HydrophobicContact CD1-CE3 3.87Å; I48-W185 HydrophobicContact CD1-CG 4.31Å; I48-W185 HydrophobicContact CG2-CB 3.79Å; I48-W185 HydrophobicContact CG2-CD2 3.97Å; I48-W185 HydrophobicContact CG2-CG 3.5Å; I48-W185 VanDerWaalsContact CG2-CG 3.5Å; V60-W185 HydrophobicContact CG1-CH2 4.48Å; V60-W185 HydrophobicContact CG1-CZ2 3.97Å; V60-W185 HydrophobicContact CG2-CH2 4.5Å; V60-W185 HydrophobicContact CG2-CZ2 4.34Å; K78-W185 HydrophobicContact CB-CH2 3.73Å; K78-W185 HydrophobicContact CB-CZ2 4.12Å; K78-W185 HydrophobicContact CD-CE3 4.38Å; K78-W185 HydrophobicContact CD-CH2 3.48Å; K78-W185 VanDerWaalsContact CD-CH2 3.48Å; K78-W185 HydrophobicContact CD-CZ2 4.02Å; K78-W185 HydrophobicContact CD-CZ3 3.68Å; K78-W185 HydrophobicContact CG-CH2 4.21Å; V80-W185 HydrophobicContact CG2-CH2 4.33Å; V80-W185 HydrophobicContact CG2-CZ3 3.83Å; H122-W185 HydrophobicContact CB-CH2 4.29Å; H122-W185 HydrophobicContact CB-CZ2 3.64Å; L124-W185 HydrophobicContact CB-CH2 4.42Å; L124-W185 HydrophobicContact CB-CZ3 4.41Å; L124-W185 HydrophobicContact CD2-CZ3 4.15Å; A181-W185 VanDerWaalsContact O-CB 3.3Å; A181-W185 WeakPolarHBondContact O-CB 3.26Å; A181-W185 PolarHBondContact O-N 2.94Å; V182-W185 WeakPolarHBondContact O-CB 3.22Å; V182-W185 PolarHBondContact O-N 3.4Å; I183-W185 VanDerWaalsContact C-N 3.29Å; I183-W185 PolarHBondContact O-N 3.49Å; W185-R187 PolarHBondContact O-N 2.54Å; W185-R187 VanDerWaalsContact O-N 3.15Å; W185-S188 WeakPolarHBondContact O-CB 3.34Å; W185-S188 PolarHBondContact O-N 3.49Å; W185-S188 PolarHBondContact O-OG 2.92Å; W185-F191 HydrophobicContact CD2-CE2 4.08Å; W185-F191 HydrophobicContact CD2-CZ 4.25Å; W185-F191 AromaticContact CE2-CE2 3.61Å; W185-F191 AromaticContact CE2-CZ 3.34Å; W185-F191 HydrophobicContact CG-CE2 4.33Å; W185-F191 HydrophobicContact CH2-CZ 4.27Å; W185-F191 HydrophobicContact CZ2-CE1 4.01Å; W185-F191 AromaticContact CZ2-CE2 3.95Å; W185-F191 HydrophobicContact CZ2-CE2 3.95Å; W185-F191 AromaticContact CZ2-CZ 3.33Å; W185-F191 HydrophobicContact CZ2-CZ 3.33Å; W185-F191 AromaticContact NE1-CE2 3.55Å; W185-F191 AromaticContact NE1-CZ 3.31Å; W185-F191 VanDerWaalsContact NE1-CZ 3.31Å
186L97.9Very high97.7Very high10 Ų1026 Ų265%0.05214%0.137CC..Hα-helixtrans-58.6-25.3174.6-75.4170.4000113.3K78 V182 I183 F191 Y276 N277 A281K78-L186 HydrophobicContact CD-CD2 4.45Å; V182-L186 HydrophobicContact CG1-CD1 4.11Å; V182-L186 HydrophobicContact CG1-CG 4.35Å; V182-L186 WeakPolarHBondContact O-CB 3.34Å; V182-L186 VanDerWaalsContact O-CG 3.31Å; V182-L186 WeakPolarHBondContact O-CG 3.49Å; V182-L186 PolarHBondContact O-N 2.91Å; I183-L186 PolarHBondContact O-N 3.39Å; L186-F191 HydrophobicContact CD2-CD2 4.06Å; L186-Y276 HydrophobicContact CD1-CD1 3.66Å; L186-Y276 HydrophobicContact CD1-CE1 3.64Å; L186-N277 VanDerWaalsContact CD2-OD1 3.24Å; L186-N277 WeakPolarHBondContact CD2-OD1 3.42Å; L186-A281 HydrophobicContact CB-CB 4.04Å; L186-A281 HydrophobicContact CD1-CB 4.2Å; L186-A281 HydrophobicContact CD2-CB 3.9Å; L186-A281 HydrophobicContact CG-CB 4.28Å
187R94.8Very high97.8Very high146 Ų14624.4 Ų24.455%0.55113%0.129SC*.Hα-helixtrans-85.9-20.2175-68.3171.6168.7152.1-1113.8E172 I183 G184 W185 Y422E172-R187 VanDerWaalsContact CD-NH2 3.27Å; E172-R187 IonicContact OE1-NH2 2.67Å; E172-R187 PolarHBondContact OE1-NH2 3.44Å; E172-R187 IonicContact OE2-CZ 3.95Å; E172-R187 IonicContact OE2-NH1 3.83Å; E172-R187 PolarHBondContact OE2-NH1 2.81Å; E172-R187 IonicContact OE2-NH2 3.05Å; E172-R187 PolarHBondContact OE2-NH2 3.13Å; I183-R187 PolarHBondContact O-N 2.96Å; G184-R187 PolarHBondContact O-N 3.18Å; W185-R187 PolarHBondContact O-N 2.54Å; W185-R187 VanDerWaalsContact O-N 3.15Å; R187-Y422 PolarHBondContact NH2-OH 3.27Å
188S95.5Very high97.9Very high73 Ų7323.6 Ų23.651%0.5112%0.122SC..Hα-helixtrans-80.3-22.2-174.370.50000113.6G184 W185G184-S188 PolarHBondContact O-N 3.32Å; W185-S188 WeakPolarHBondContact O-CB 3.34Å; W185-S188 PolarHBondContact O-N 3.49Å; W185-S188 PolarHBondContact O-OG 2.92Å
189E95.9Very high97.8Very high39 Ų3923.8 Ų23.818%0.18212%0.124CC..SBendtrans-137.2157.2-176.6-61.7-69.8-16800110.1E76 R120 F191E76-E189 HydrophobicContact CG-CB 4.42Å; R120-E189 IonicContact CZ-OE1 3.88Å; R120-E189 IonicContact NH1-OE1 3.24Å; R120-E189 PolarHBondContact NH1-OE1 3.47Å; R120-E189 IonicContact NH1-OE2 3.95Å; R120-E189 PolarHBondContact NH1-OE2 2.92Å; R120-E189 IonicContact NH2-OE1 2.89Å; R120-E189 PolarHBondContact NH2-OE1 3.05Å; E189-F191 HydrophobicContact CB-CD2 4.13Å; E189-F191 HydrophobicContact CB-CE1 4.41Å; E189-F191 HydrophobicContact CB-CE2 3.69Å; E189-F191 HydrophobicContact CB-CZ 3.81Å; E189-F191 HydrophobicContact CG-CE2 4.33Å; E189-F191 HydrophobicContact CG-CZ 4.17Å; E189-F191 PolarHBondContact O-N 3.1Å
190T96.6Very high97.6Very high38 Ų3824.7 Ų24.723%0.23313%0.134CC..  trans-91.171.4176.8-51.30000110.3E76 V192 N354 Y360E76-T190 WeakPolarHBondContact CB-O 3.32Å; T190-V192 PolarHBondContact O-N 3.04Å; T190-N354 HydrophobicContact CG2-CB 4.27Å; T190-N354 WeakPolarHBondContact OG1-CB 3.18Å; T190-N354 PolarHBondContact OG1-ND2 2.94Å; T190-N354 VanDerWaalsContact OG1-ND2 3.11Å; T190-Y360 HydrophobicContact CG2-CD2 4.28Å
191F98.8Very high97.5Very high5 Ų519.2 Ų19.22%0.02211%0.113CC..EExtended strand (participates in β ladder)trans-62.2130.8177.9-70.5-65.7000111.9E76 K78 H122 W185 L186 E189 C283E76-F191 HydrophobicContact CB-CD1 3.86Å; E76-F191 HydrophobicContact CB-CE1 4.15Å; K78-F191 HydrophobicContact CB-CD1 3.84Å; K78-F191 HydrophobicContact CB-CE1 3.69Å; K78-F191 HydrophobicContact CB-CZ 4.38Å; K78-F191 HydrophobicContact CD-CD1 3.76Å; K78-F191 HydrophobicContact CD-CD2 3.91Å; K78-F191 HydrophobicContact CD-CE1 3.9Å; K78-F191 HydrophobicContact CD-CE2 4.01Å; K78-F191 HydrophobicContact CD-CG 3.78Å; K78-F191 HydrophobicContact CD-CZ 4.04Å; K78-F191 HydrophobicContact CG-CD1 3.75Å; K78-F191 HydrophobicContact CG-CE1 4.03Å; K78-F191 HydrophobicContact CG-CG 4.16Å; H122-F191 HydrophobicContact CB-CE1 4.07Å; H122-F191 HydrophobicContact CB-CZ 4.39Å; H122-F191 AromaticContact CD2-CE1 3.65Å; H122-F191 AromaticContact CG-CE1 3.81Å; W185-F191 HydrophobicContact CD2-CE2 4.08Å; W185-F191 HydrophobicContact CD2-CZ 4.25Å; W185-F191 AromaticContact CE2-CE2 3.61Å; W185-F191 AromaticContact CE2-CZ 3.34Å; W185-F191 HydrophobicContact CG-CE2 4.33Å; W185-F191 HydrophobicContact CH2-CZ 4.27Å; W185-F191 HydrophobicContact CZ2-CE1 4.01Å; W185-F191 AromaticContact CZ2-CE2 3.95Å; W185-F191 HydrophobicContact CZ2-CE2 3.95Å; W185-F191 AromaticContact CZ2-CZ 3.33Å; W185-F191 HydrophobicContact CZ2-CZ 3.33Å; W185-F191 AromaticContact NE1-CE2 3.55Å; W185-F191 AromaticContact NE1-CZ 3.31Å; W185-F191 VanDerWaalsContact NE1-CZ 3.31Å; L186-F191 HydrophobicContact CD2-CD2 4.06Å; E189-F191 HydrophobicContact CB-CD2 4.13Å; E189-F191 HydrophobicContact CB-CE1 4.41Å; E189-F191 HydrophobicContact CB-CE2 3.69Å; E189-F191 HydrophobicContact CB-CZ 3.81Å; E189-F191 HydrophobicContact CG-CE2 4.33Å; E189-F191 HydrophobicContact CG-CZ 4.17Å; E189-F191 PolarHBondContact O-N 3.1Å; F191-C283 HydrophobicContact CB-CB 3.97Å; F191-C283 WeakPolarHBondContact O-CB 3.37Å
192V98.9Very high97.4Very high7 Ų719.9 Ų19.94%0.04212%0.115CC..EExtended strand (participates in β ladder)trans-103.7-47-176.6-179.40000111.2P75 E76 T190 L284 V319 Y360 L362P75-V192 HydrophobicContact CB-CB 4.33Å; P75-V192 HydrophobicContact CB-CG2 3.88Å; E76-V192 PolarHBondContact O-N 3.31Å; T190-V192 PolarHBondContact O-N 3.04Å; V192-L284 PolarHBondContact O-N 2.92Å; V192-L284 VanDerWaalsContact O-N 3.11Å; V192-V319 HydrophobicContact CB-CG2 3.85Å; V192-V319 HydrophobicContact CG1-CG2 4.02Å; V192-Y360 HydrophobicContact CG1-CG 4.43Å; V192-Y360 HydrophobicContact CG2-CD1 3.83Å; V192-Y360 HydrophobicContact CG2-CD2 3.84Å; V192-Y360 HydrophobicContact CG2-CE1 4.47Å; V192-Y360 HydrophobicContact CG2-CG 3.49Å; V192-Y360 VanDerWaalsContact CG2-CG 3.49Å; V192-L362 HydrophobicContact CG1-CD1 4.16Å; V192-L362 HydrophobicContact CG1-CD2 3.78Å; V192-L362 HydrophobicContact CG1-CG 3.9Å
193L98.9Very high97.4Very high0 Ų019.9 Ų19.90%012%0.115CC..EExtended strand (participates in β ladder)trans-134.3142.2-178.8-177.366.6000109.8F77 K78 L233 L284 Y315 Q318 V319 L362F77-L193 WeakPolarHBondContact CA-O 3.48Å; F77-L193 HydrophobicContact CD2-CB 3.94Å; F77-L193 HydrophobicContact CD2-CD2 4.05Å; F77-L193 HydrophobicContact CD2-CG 4.02Å; F77-L193 WeakPolarHBondContact CD2-O 3.22Å; F77-L193 HydrophobicContact CE2-CB 4.32Å; F77-L193 HydrophobicContact CE2-CD2 3.91Å; F77-L193 HydrophobicContact CE2-CG 3.9Å; K78-L193 PolarHBondContact N-O 2.85Å; K78-L193 VanDerWaalsContact N-O 3.08Å; L193-L233 HydrophobicContact CD1-CD1 3.67Å; L193-L233 HydrophobicContact CD1-CD2 3.97Å; L193-L233 HydrophobicContact CD1-CG 4.46Å; L193-L233 HydrophobicContact CD2-CD2 4.23Å; L193-L284 CarbonylContact C-O 3.5Å; L193-L284 WeakPolarHBondContact CA-O 3.49Å; L193-L284 HydrophobicContact CD1-CB 4.28Å; L193-Y315 HydrophobicContact CD1-CE1 4.28Å; L193-Y315 WeakPolarHBondContact CD1-OH 3.18Å; L193-Y315 HydrophobicContact CD2-CD1 4.46Å; L193-Y315 HydrophobicContact CD2-CE1 4.13Å; L193-Y315 WeakPolarHBondContact CD2-O 3.39Å; L193-Y315 HydrophobicContact CG-CE1 4.01Å; L193-Q318 HydrophobicContact CD2-CB 3.88Å; L193-V319 HydrophobicContact CB-CB 4.05Å; L193-V319 HydrophobicContact CB-CG2 3.8Å; L193-V319 HydrophobicContact CD2-CB 4.12Å; L193-L362 HydrophobicContact CB-CD1 4.15Å; L193-L362 HydrophobicContact CD1-CD1 4Å
194S98.9Very high97.4Very high0 Ų019.8 Ų19.80%011%0.114CC..EExtended strand (participates in β ladder)trans-143.3159.4179.6-179.50000112.5K78 C283 L284 E285 L286 Y315K78-S194 WeakPolarHBondContact CG-OG 3.34Å; K78-S194 VanDerWaalsContact NZ-CB 3.29Å; K78-S194 PolarHBondContact NZ-OG 3.44Å; K78-S194 WeakPolarHBondContact O-CA 3.33Å; K78-S194 PolarHBondContact O-OG 3Å; S194-C283 VanDerWaalsContact CB-SG 3.52Å; S194-L284 PolarHBondContact N-O 3.36Å; S194-E285 VanDerWaalsContact CB-OE2 3.3Å; S194-E285 WeakPolarHBondContact CB-OE2 3.47Å; S194-E285 WeakPolarHBondContact O-CA 3.45Å; S194-E285 PolarHBondContact OG-OE2 2.92Å; S194-L286 PolarHBondContact O-N 3.43Å; S194-Y315 WeakPolarHBondContact O-CE1 3.05Å; S194-Y315 PolarHBondContact O-OH 2.82Å
195A98.9Very high97.5Very high0 Ų018.1 Ų18.10%010%0.097CC..EExtended strand (participates in β ladder)trans-140148.6152.100000111.4K78 Y79 V80 L197 L286 L288 Y315K78-A195 PolarHBondContact O-N 2.87Å; Y79-A195 WeakPolarHBondContact CA-O 3.29Å; Y79-A195 HydrophobicContact CD1-CB 3.81Å; Y79-A195 WeakPolarHBondContact CD1-O 3.45Å; Y79-A195 HydrophobicContact CE1-CB 3.47Å; Y79-A195 VanDerWaalsContact CE1-CB 3.47Å; V80-A195 PolarHBondContact N-O 3.31Å; A195-L197 HydrophobicContact CB-CD1 4.4Å; A195-L286 CarbonylContact C-O 3.6Å; A195-L286 WeakPolarHBondContact CA-O 3.33Å; A195-L286 HydrophobicContact CB-CB 4.39Å; A195-L288 HydrophobicContact CB-CD1 3.54Å; A195-L288 HydrophobicContact CB-CG 3.87Å; A195-Y315 HydrophobicContact CB-CD1 4.37Å; A195-Y315 HydrophobicContact CB-CE1 3.65Å
196N98.8Very high97.5Very high1 Ų119.2 Ų19.21%0.00510%0.101CC..EExtended strand (participates in β ladder)trans-107.7134.317072.371.6000109.9V80 H198 M273 E285 L286 T287 L288V80-N196 HydrophobicContact CB-CB 4.38Å; V80-N196 CarbonylContact O-C 3.54Å; V80-N196 VanDerWaalsContact O-CA 3.24Å; V80-N196 WeakPolarHBondContact O-CA 3.39Å; N196-H198 PolarHBondContact OD1-CD2 3.4Å; N196-H198 PolarHBondContact OD1-NE2 3.1Å; N196-M273 HydrophobicContact CB-CE 3.32Å; N196-E285 PolarHBondContact ND2-OE1 3.41Å; N196-L286 PolarHBondContact N-O 3.09Å; N196-L286 PolarHBondContact ND2-O 3.25Å; N196-T287 PolarHBondContact ND2-OG1 2.97Å; N196-T287 WeakPolarHBondContact O-CA 3.43Å; N196-T287 WeakPolarHBondContact OD1-CG2 3.36Å; N196-T287 PolarHBondContact OD1-OG1 3.23Å; N196-L288 PolarHBondContact O-N 3.18Å
197L98.9Very high97.5Very high2 Ų218.8 Ų18.81%0.0110%0.099CC..EExtended strand (participates in β ladder)trans-106.5127.1-168.2-7761.7000110.7Y79 V80 A81 L94 A195 L288 L290 L312Y79-L197 HydrophobicContact CD1-CD1 3.43Å; Y79-L197 VanDerWaalsContact CD1-CD1 3.43Å; Y79-L197 HydrophobicContact CE1-CD1 3.82Å; Y79-L197 HydrophobicContact CG-CD1 4.29Å; V80-L197 PolarHBondContact O-N 3.16Å; A81-L197 HydrophobicContact CB-CB 3.91Å; A81-L197 HydrophobicContact CB-CD2 4.46Å; L94-L197 HydrophobicContact CD1-CD2 4.43Å; L94-L197 HydrophobicContact CD2-CD2 3.82Å; L94-L197 HydrophobicContact CG-CD2 3.95Å; A195-L197 HydrophobicContact CB-CD1 4.4Å; L197-L288 HydrophobicContact CD1-CD1 4.27Å; L197-L290 HydrophobicContact CB-CD1 3.85Å; L197-L290 HydrophobicContact CD2-CD1 3.81Å; L197-L290 HydrophobicContact CG-CD1 3.82Å; L197-L312 HydrophobicContact CD2-CD2 4.29Å
198H98.7Very high97.6Very high4 Ų412.1 Ų12.12%0.0197%0.074CC..EExtended strand (participates in β ladder)trans-127.9174-173.3-79.6-93.8000112.4M83 H84 E87 N196 T287 L288 E289 L290M83-H198 WeakPolarHBondContact CG-CE1 3.41Å; M83-H198 WeakPolarHBondContact CG-NE2 3.23Å; M83-H198 PolarHBondContact SD-CE1 3.42Å; M83-H198 PolarHBondContact SD-NE2 3.04Å; H84-H198 AromaticContact CE1-CE1 3.31Å; H84-H198 PolarHBondContact CE1-CE1 3.36Å; H84-H198 AromaticContact CE1-ND1 3.57Å; H84-H198 AromaticContact ND1-CE1 3.33Å; H84-H198 PolarHBondContact ND1-CE1 2.96Å; H84-H198 VanDerWaalsContact ND1-CE1 3.33Å; H84-H198 AromaticContact ND1-ND1 3.26Å; H84-H198 PolarHBondContact ND1-ND1 3.32Å; E87-H198 WeakPolarHBondContact OE2-CB 3.31Å; E87-H198 IonicContact OE2-CE1 2.88Å; E87-H198 IonicContact OE2-CG 3.06Å; E87-H198 IonicContact OE2-ND1 3.55Å; E87-H198 PolarHBondContact OE2-ND1 3.27Å; N196-H198 PolarHBondContact OD1-CD2 3.4Å; N196-H198 PolarHBondContact OD1-NE2 3.1Å; H198-T287 HydrophobicContact CB-CG2 4.45Å; H198-L288 PolarHBondContact N-O 2.89Å; H198-E289 VanDerWaalsContact CB-CD 3.42Å; H198-E289 HydrophobicContact CB-CG 4.37Å; H198-E289 WeakPolarHBondContact CB-OE1 3.37Å; H198-E289 VanDerWaalsContact CB-OE2 3.31Å; H198-E289 WeakPolarHBondContact CB-OE2 3.18Å; H198-L290 PolarHBondContact O-N 3.03Å
199G96.4Very high97.6Very high3 Ų38.9 Ų8.93%0.0315%0.051CC..  trans-145.2158.2170.600000111.6E87 E289E87-G199 VanDerWaalsContact CG-O 3.3Å; E87-G199 WeakPolarHBondContact CG-O 3.39Å; E87-G199 PolarHBondContact OE2-N 3.05Å; G199-E289 WeakPolarHBondContact CA-OE2 2.91Å; G199-E289 PolarHBondContact N-OE2 2.84Å
200G94.3Very high97.4Very high20 Ų207.1 Ų7.121%0.2064%0.042CC..SBendtrans121.1-12.9-17300000112.9S291 C292G200-S291 PolarHBondContact N-O 3.41Å; G200-C292 WeakPolarHBondContact CA-O 3.36Å
201A95.3Very high96.9Very high1 Ų15.6 Ų5.61%0.0083%0.033CC..EExtended strand (participates in β ladder)trans-146.5-176.8170.500000110.5V203 W266 E289 S291A201-V203 HydrophobicContact CB-CG1 4.29Å; A201-W266 HydrophobicContact CB-CH2 3.77Å; A201-W266 HydrophobicContact CB-CZ2 3.87Å; A201-E289 HydrophobicContact CB-CB 3.89Å; A201-E289 HydrophobicContact CB-CG 4.05Å; A201-E289 CarbonylContact O-C 3.2Å; A201-E289 WeakPolarHBondContact O-CB 3.42Å; A201-S291 PolarHBondContact N-O 2.82Å; A201-S291 CarbonylContact O-C 3.57Å; A201-S291 PolarHBondContact O-N 2.99Å; A201-S291 VanDerWaalsContact O-N 3.15Å; A201-S291 VanDerWaalsContact O-O 3.09Å
202M96.2Very high95.8Very high24 Ų249.7 Ų9.712%0.1186%0.055CC..EExtended strand (participates in β ladder)trans-134.385.6172.3-161.9176.4-60.800111M244 L249 E289M202-M244 HydrophobicContact CG-CB 4.38Å; M202-M244 HydrophobicContact CG-CE 4.2Å; M202-M244 HydrophobicContact CG-CG 4.33Å; M202-L249 HydrophobicContact CB-CB 4.26Å; M202-L249 HydrophobicContact CB-CD1 4.25Å; M202-L249 HydrophobicContact CG-CD1 3.93Å; M202-L249 HydrophobicContact SD-CB 4.14Å; M202-L249 HydrophobicContact SD-CD1 3.23Å; M202-L249 WeakPolarHBondContact SD-CD1 3.44Å; M202-L249 HydrophobicContact SD-CG 4.22Å; M202-E289 WeakPolarHBondContact CA-O 3.22Å
203V98.1Very high94.1Very high0 Ų014 Ų140%08%0.075CC..EExtended strand (participates in β ladder)trans-162.3147.5-173.2630000111.1A201 F256 T261 W266 E289A201-V203 HydrophobicContact CB-CG1 4.29Å; V203-F256 HydrophobicContact CB-CB 4.36Å; V203-F256 HydrophobicContact CB-CD1 4.34Å; V203-F256 HydrophobicContact CB-CD2 3.58Å; V203-F256 HydrophobicContact CB-CE2 3.8Å; V203-F256 HydrophobicContact CB-CG 3.85Å; V203-F256 HydrophobicContact CB-CZ 4.29Å; V203-F256 HydrophobicContact CG1-CD2 4.12Å; V203-F256 HydrophobicContact CG1-CE1 4.39Å; V203-F256 HydrophobicContact CG1-CE2 3.79Å; V203-F256 HydrophobicContact CG1-CZ 3.94Å; V203-F256 HydrophobicContact CG2-CB 3.8Å; V203-F256 HydrophobicContact CG2-CD1 3.78Å; V203-F256 HydrophobicContact CG2-CD2 3.84Å; V203-F256 HydrophobicContact CG2-CE1 4.27Å; V203-F256 HydrophobicContact CG2-CE2 4.3Å; V203-F256 HydrophobicContact CG2-CG 3.54Å; V203-F256 HydrophobicContact CG2-CZ 4.5Å; V203-T261 HydrophobicContact CG1-CG2 4.35Å; V203-T261 HydrophobicContact CG2-CG2 3.7Å; V203-W266 HydrophobicContact CG1-CE3 4.42Å; V203-W266 HydrophobicContact CG1-CH2 4.3Å; V203-W266 HydrophobicContact CG1-CZ3 4.07Å; V203-E289 HydrophobicContact CG1-CB 3.99Å; V203-E289 HydrophobicContact CG1-CG 4.06Å; V203-E289 PolarHBondContact N-O 3.04Å; V203-E289 VanDerWaalsContact N-O 3.14Å; V203-E289 WeakPolarHBondContact O-CB 2.82Å; V203-E289 PolarHBondContact O-N 2.91Å
204A98.6Very high91.8Very high0 Ų017.5 Ų17.50%011%0.111CC..EExtended strand (participates in β ladder)trans-92106.2164.900000109.9A234 M244 G259 I260 T261 L288A204-A234 HydrophobicContact CB-CB 3.91Å; A204-M244 HydrophobicContact CB-SD 4.15Å; A204-G259 PolarHBondContact N-O 3.17Å; A204-I260 HydrophobicContact CB-CG2 4.33Å; A204-I260 VanDerWaalsContact O-CA 3.29Å; A204-I260 WeakPolarHBondContact O-CA 3.41Å; A204-T261 PolarHBondContact O-N 3.35Å; A204-L288 HydrophobicContact CB-CD2 3.81Å
205S98.6Very high89.4Confident3 Ų319.9 Ų19.92%0.02113%0.128CC..EExtended strand (participates in β ladder)trans-88138.2177.1-173.20000110.7T261 G263 Q274 T287S205-T261 CarbonylContact C-O 3.51Å; S205-T261 VanDerWaalsContact CA-O 3.28Å; S205-T261 WeakPolarHBondContact CA-O 3.04Å; S205-G263 WeakPolarHBondContact OG-CA 3.28Å; S205-Q274 PolarHBondContact O-OE1 3.47Å; S205-Q274 VanDerWaalsContact O-OE1 3.11Å; S205-T287 PolarHBondContact N-O 3.27Å; S205-T287 PolarHBondContact O-N 3.34Å
206Y98.8Very high87.2Confident28 Ų2826 Ų2611%0.1116%0.164CC..EExtended strand (participates in β ladder)trans-130155.6-17861.3-93.8000113.1F230 V231 A234 I260 T261 N262 G263Y206-F230 HydrophobicContact CD2-CB 4.04Å; Y206-F230 HydrophobicContact CG-CB 4.24Å; Y206-V231 HydrophobicContact CE1-CG2 4.17Å; Y206-V231 HydrophobicContact CE2-CG2 3.84Å; Y206-A234 HydrophobicContact CD1-CB 3.95Å; Y206-I260 HydrophobicContact CE1-CB 4.25Å; Y206-I260 HydrophobicContact CE1-CD1 4.01Å; Y206-I260 HydrophobicContact CE1-CG1 4.31Å; Y206-T261 VanDerWaalsContact CD1-C 3.49Å; Y206-T261 WeakPolarHBondContact CD1-O 3.44Å; Y206-T261 WeakPolarHBondContact CE1-O 3.36Å; Y206-T261 PolarHBondContact N-O 2.83Å; Y206-N262 HydrophobicContact CD2-CB 4.43Å; Y206-N262 HydrophobicContact CE2-CB 3.77Å; Y206-G263 PolarHBondContact O-N 2.84Å
207P98.3Very high84.7Confident0 Ų036.9 Ų36.90%021%0.206CC..SBendtrans-55.8155-178.6-32.438.4000116A224 F230 N262 Q274 E285P207-A224 HydrophobicContact CB-CB 4.47Å; P207-F230 HydrophobicContact CB-CD2 4.45Å; P207-F230 HydrophobicContact CB-CE2 4.08Å; P207-F230 HydrophobicContact CB-CZ 4.11Å; P207-F230 HydrophobicContact CG-CD1 4.17Å; P207-F230 HydrophobicContact CG-CE1 3.65Å; P207-F230 HydrophobicContact CG-CE2 4.06Å; P207-F230 HydrophobicContact CG-CZ 3.58Å; P207-N262 PolarHBondContact O-ND2 2.93Å; P207-N262 VanDerWaalsContact O-ND2 3.08Å; P207-Q274 HydrophobicContact CG-CG 3.83Å; P207-E285 WeakPolarHBondContact CD-O 2.97Å
208Y96.9Very high82.3Confident7 Ų742.9 Ų42.93%0.02724%0.235CC..  cis-86.5150.8-7-66.8-74000112.6F161 N210 S222 A224 N262 Y264 D275 Y278 V279 M348F161-Y208 AromaticContact CE2-CD1 3.93Å; F161-Y208 HydrophobicContact CE2-CD1 3.93Å; F161-Y208 HydrophobicContact CE2-CE1 4.48Å; F161-Y208 AromaticContact CE2-CG 3.99Å; F161-Y208 HydrophobicContact CE2-CG 3.99Å; F161-Y208 AromaticContact CZ-CD1 3.93Å; F161-Y208 HydrophobicContact CZ-CD1 3.93Å; F161-Y208 AromaticContact CZ-CD2 3.87Å; F161-Y208 HydrophobicContact CZ-CD2 3.87Å; F161-Y208 HydrophobicContact CZ-CE1 4.33Å; F161-Y208 HydrophobicContact CZ-CE2 4.24Å; F161-Y208 AromaticContact CZ-CG 3.68Å; F161-Y208 HydrophobicContact CZ-CG 3.68Å; Y208-N210 WeakPolarHBondContact CB-O 3.37Å; Y208-S222 PolarHBondContact N-O 3.28Å; Y208-A224 HydrophobicContact CD2-CB 4.08Å; Y208-A224 VanDerWaalsContact CE2-CA 3.49Å; Y208-A224 HydrophobicContact CE2-CB 3.83Å; Y208-N262 PolarHBondContact N-ND2 3.21Å; Y208-Y264 WeakPolarHBondContact O-CB 3.49Å; Y208-Y264 PolarHBondContact O-N 3.18Å; Y208-D275 WeakPolarHBondContact CA-OD1 3.48Å; Y208-D275 HydrophobicContact CD1-CB 4.41Å; Y208-Y278 HydrophobicContact CD1-CD1 4.5Å; Y208-Y278 AromaticContact CE1-CD1 3.6Å; Y208-Y278 HydrophobicContact CE1-CD1 3.6Å; Y208-Y278 AromaticContact CE1-CE1 3.9Å; Y208-Y278 HydrophobicContact CE1-CE1 3.9Å; Y208-Y278 AromaticContact CZ-CD1 3.9Å; Y208-Y278 AromaticContact CZ-CE1 3.68Å; Y208-Y278 WeakPolarHBondContact OH-CE1 3.36Å; Y208-V279 HydrophobicContact CE1-CG2 3.95Å; Y208-M348 HydrophobicContact CE1-CE 4.49Å; Y208-M348 HydrophobicContact CE2-CE 4.3Å
209D95.5Very high80.3Confident5 Ų548.3 Ų48.33%0.02727%0.269CS..SBendtrans-81.1-21.8172.3-78.9-14.3000112.3G263 L269 Q274 D275D209-G263 WeakPolarHBondContact OD1-CA 3.41Å; D209-L269 CarbonylContact C-O 3.48Å; D209-L269 HydrophobicContact CB-CB 4.03Å; D209-L269 HydrophobicContact CB-CD2 4.02Å; D209-L269 HydrophobicContact CB-CG 4.45Å; D209-L269 PolarHBondContact O-N 2.63Å; D209-Q274 PolarHBondContact OD1-NE2 2.83Å; D209-Q274 PolarHBondContact OD2-NE2 2.77Å; D209-Q274 VanDerWaalsContact OD2-NE2 3.16Å; D209-D275 PolarHBondContact N-OD1 2.8Å; D209-D275 VanDerWaalsContact N-OD1 3.07Å; D209-D275 PolarHBondContact N-OD2 2.93Å
210N91.8Very high79.2Confident1 Ų150.6 Ų50.61%0.00528%0.284CS..  trans-127.9171.3179.7-156.60.4000112.9D159 F161 Y208 S222 K268 L269 D275D159-N210 VanDerWaalsContact CG-ND2 3.25Å; D159-N210 PolarHBondContact OD1-ND2 2.93Å; D159-N210 PolarHBondContact OD2-ND2 3.2Å; F161-N210 HydrophobicContact CB-CB 4.5Å; F161-N210 HydrophobicContact CD2-CB 3.62Å; F161-N210 HydrophobicContact CE2-CB 4.1Å; F161-N210 WeakPolarHBondContact CE2-O 3.36Å; F161-N210 HydrophobicContact CG-CB 4.3Å; F161-N210 WeakPolarHBondContact CZ-O 3.32Å; Y208-N210 WeakPolarHBondContact CB-O 3.37Å; N210-S222 VanDerWaalsContact O-CB 3.22Å; N210-S222 WeakPolarHBondContact O-CB 3.19Å; N210-S222 PolarHBondContact O-OG 3.09Å; N210-K268 WeakPolarHBondContact OD1-CE 3.21Å; N210-L269 WeakPolarHBondContact CB-O 3.12Å; N210-D275 PolarHBondContact N-OD2 3.49Å
211S86.4Confident78.8Confident6 Ų652.4 Ų52.44%0.04229%0.292CS..  trans-149.6153.7178.7-170.10000112.7Q213 Y264S211-Q213 VanDerWaalsContact C-N 3.32Å; S211-Q213 PolarHBondContact OG-N 3.39Å; S211-Y264 VanDerWaalsContact CB-CZ 3.45Å
212D74Confident78.7Confident92 Ų9252.7 Ų52.749%0.49229%0.294SS..SBendtrans-83.9-5.4171.568.2-17.1000113.1F161 L164 R165 G214F161-D212 HydrophobicContact CD1-CB 4.03Å; F161-D212 VanDerWaalsContact CD1-N 3.29Å; L164-D212 HydrophobicContact CD1-CB 4.1Å; R165-D212 PolarHBondContact NH2-O 2.79Å; D212-G214 PolarHBondContact O-N 3.28Å
213Q64.6Low78.6Confident97 Ų9756 Ų5645%0.45331%0.311SS..  trans-72127.8178.2-61.2-167.317.900111.1R165 S211 S215R165-Q213 PolarHBondContact NH2-O 3.18Å; S211-Q213 VanDerWaalsContact C-N 3.32Å; S211-Q213 PolarHBondContact OG-N 3.39Å; Q213-S215 PolarHBondContact O-N 2.87Å
214G50.9Low78.5Confident73 Ų7356.1 Ų56.175%0.75331%0.313SS*.  trans-83.34.1-16300000116.7D212D212-G214 PolarHBondContact O-N 3.28Å
215S48.6Very low78.4Confident51 Ų5157.9 Ų57.936%0.35732%0.324SS..  trans-131.3120.6-174.859.30000112.5Q213 W217 M218Q213-S215 PolarHBondContact O-N 2.87Å; S215-W217 PolarHBondContact O-N 2.89Å; S215-M218 PolarHBondContact O-N 3.01Å
216V52.2Low78.4Confident127 Ų12757.8 Ų57.877%0.7732%0.323SS*.THydrogen-bonded Turntrans-54.6-12.6168.4179.20000112.4
217W46.7Very low78.4Confident231 Ų23158.2 Ų58.288%0.87533%0.328SS*.THydrogen-bonded Turntrans-94-0.6-170.8-55.6115.9000115.6S215S215-W217 PolarHBondContact O-N 2.89Å
218M47.3Very low78.4Confident127 Ų12761.1 Ų61.163%0.62634%0.343SS*.  trans-125.3102.1172.8-107.1175.7153.300109.2S215 S220S215-M218 PolarHBondContact O-N 3.01Å; M218-S220 PolarHBondContact O-N 2.9Å
219V57.4Low78.5Confident119 Ų11960.8 Ų60.872%0.72134%0.342SS*.  trans-74.763.7175.5-1700000109.1
220S72.5Confident78.7Confident50 Ų5060.6 Ų60.635%0.3534%0.34SS..  trans-94.6135.6169-66.60000108.8M218 Y264M218-S220 PolarHBondContact O-N 2.9Å; S220-Y264 WeakPolarHBondContact O-CD1 3.25Å
221P86.1Confident79Confident58 Ų5862 Ų6238%0.37735%0.349SS..  trans-59.8145.7177.325.5-34.3000111.2I223 N262 S265P221-I223 HydrophobicContact CB-CD1 3.6Å; P221-I223 HydrophobicContact CB-CG1 4.17Å; P221-I223 HydrophobicContact CG-CD1 3.65Å; P221-I223 HydrophobicContact CG-CG1 4.03Å; P221-I223 PolarHBondContact O-N 3.24Å; P221-N262 HydrophobicContact CB-CB 4.19Å; P221-S265 VanDerWaalsContact CA-OG 3.26Å; P221-S265 WeakPolarHBondContact CA-OG 3.4Å; P221-S265 WeakPolarHBondContact CB-OG 3.36Å
222S93Very high79.6Confident8 Ų864 Ų646%0.05636%0.358CS..  trans-89.593.3172.5-166.10000108.6Y208 N210 N262Y208-S222 PolarHBondContact N-O 3.28Å; N210-S222 VanDerWaalsContact O-CB 3.22Å; N210-S222 WeakPolarHBondContact O-CB 3.19Å; N210-S222 PolarHBondContact O-OG 3.09Å; S222-N262 PolarHBondContact N-OD1 2.73Å; S222-N262 VanDerWaalsContact N-OD1 3.1Å; S222-N262 PolarHBondContact O-ND2 2.94Å
223I94.3Very high80.8Confident92 Ų9259.6 Ų59.647%0.47233%0.334SS..  trans-82.2125.4-166.8-60.2-63.6000111.6P221 D227P221-I223 HydrophobicContact CB-CD1 3.6Å; P221-I223 HydrophobicContact CB-CG1 4.17Å; P221-I223 HydrophobicContact CG-CD1 3.65Å; P221-I223 HydrophobicContact CG-CG1 4.03Å; P221-I223 PolarHBondContact O-N 3.24Å; I223-D227 HydrophobicContact CG2-CB 3.75Å
224A95.8Very high82.4Confident4 Ų455 Ų553%0.03331%0.313CS..  trans-78.8151.6173.200000112.2P207 Y208 D226 D227 F230 Y278P207-A224 HydrophobicContact CB-CB 4.47Å; Y208-A224 HydrophobicContact CD2-CB 4.08Å; Y208-A224 VanDerWaalsContact CE2-CA 3.49Å; Y208-A224 HydrophobicContact CE2-CB 3.83Å; A224-D226 PolarHBondContact O-N 2.8Å; A224-D226 VanDerWaalsContact O-N 3.09Å; A224-D227 VanDerWaalsContact O-CB 3.24Å; A224-D227 WeakPolarHBondContact O-CB 3.34Å; A224-D227 PolarHBondContact O-N 2.72Å; A224-F230 HydrophobicContact CB-CD2 3.92Å; A224-F230 HydrophobicContact CB-CE2 3.92Å; A224-Y278 HydrophobicContact CB-CE1 3.81Å
225P97.1Very high84.7Confident37 Ų3754.9 Ų54.924%0.2429%0.291CS..THydrogen-bonded Turntrans-57.2-23.1171.7-29.336.1000114.7Y278 R345 R346P225-Y278 WeakPolarHBondContact CD-OH 3.34Å; P225-R345 HydrophobicContact CB-CB 4.36Å; P225-R346 WeakPolarHBondContact CG-O 3.26Å
226D98.3Very high87.1Confident0 Ų053.2 Ų53.20%028%0.279CS..THydrogen-bonded Turntrans-107.926.2178.1-69.7-72.5000112.3A224 D228 V229 F230 Y278 L284 R345 N347 R361A224-D226 PolarHBondContact O-N 2.8Å; A224-D226 VanDerWaalsContact O-N 3.09Å; D226-D228 VanDerWaalsContact C-N 3.33Å; D226-D228 PolarHBondContact O-N 3.04Å; D226-V229 WeakPolarHBondContact O-CB 3.07Å; D226-V229 PolarHBondContact O-N 3.48Å; D226-F230 HydrophobicContact CB-CD2 4.28Å; D226-F230 HydrophobicContact CB-CE2 4.22Å; D226-F230 WeakPolarHBondContact O-CD2 3.46Å; D226-F230 PolarHBondContact O-N 3.17Å; D226-Y278 HydrophobicContact CB-CE2 4.18Å; D226-Y278 WeakPolarHBondContact CB-OH 3.3Å; D226-Y278 PolarHBondContact N-OH 2.78Å; D226-Y278 PolarHBondContact OD2-OH 3.14Å; D226-L284 HydrophobicContact CB-CD2 4.4Å; D226-R345 WeakPolarHBondContact OD1-CD 3.33Å; D226-R345 IonicContact OD1-CZ 2.78Å; D226-R345 IonicContact OD1-NE 3.32Å; D226-R345 IonicContact OD1-NH1 2.78Å; D226-R345 PolarHBondContact OD1-NH1 2.87Å; D226-N347 PolarHBondContact OD2-ND2 2.86Å; D226-N347 VanDerWaalsContact OD2-ND2 3.09Å; D226-R361 VanDerWaalsContact CG-NH2 3.3Å; D226-R361 IonicContact OD1-CZ 3.52Å; D226-R361 IonicContact OD1-NH2 3.78Å; D226-R361 PolarHBondContact OD1-NH2 2.84Å; D226-R361 IonicContact OD2-CZ 4Å; D226-R361 IonicContact OD2-NH1 3.51Å; D226-R361 IonicContact OD2-NH2 2.7Å; D226-R361 PolarHBondContact OD2-NH2 2.93Å
227D98.5Very high89.3Confident38 Ų3847.2 Ų47.220%0.20324%0.243CC..Hα-helixtrans-53.6-42-176.4-176.979.5000114I223 A224 V229 F230 V231I223-D227 HydrophobicContact CG2-CB 3.75Å; A224-D227 VanDerWaalsContact O-CB 3.24Å; A224-D227 WeakPolarHBondContact O-CB 3.34Å; A224-D227 PolarHBondContact O-N 2.72Å; D227-V229 VanDerWaalsContact C-N 3.3Å; D227-V229 PolarHBondContact O-N 3.08Å; D227-F230 PolarHBondContact O-N 3.34Å; D227-F230 VanDerWaalsContact O-N 3.17Å; D227-V231 WeakPolarHBondContact O-CB 3.49Å; D227-V231 VanDerWaalsContact O-CG2 3.31Å; D227-V231 WeakPolarHBondContact O-CG2 3.5Å; D227-V231 PolarHBondContact O-N 3.01Å
228D98.7Very high91.8Very high61 Ų6136.2 Ų36.233%0.32620%0.201SC..Hα-helixtrans-59.3-41.117764.4-31.4000112.5D226 H232 R345 L364D226-D228 VanDerWaalsContact C-N 3.33Å; D226-D228 PolarHBondContact O-N 3.04Å; D228-H232 WeakPolarHBondContact O-CB 3.32Å; D228-H232 PolarHBondContact O-N 3.1Å; D228-R345 IonicContact OD1-CZ 2.87Å; D228-R345 VanDerWaalsContact OD1-CZ 3.28Å; D228-R345 IonicContact OD1-NH1 3.21Å; D228-R345 PolarHBondContact OD1-NH1 3.4Å; D228-R345 IonicContact OD1-NH2 3.77Å; D228-R345 PolarHBondContact OD1-NH2 3.2Å; D228-R345 IonicContact OD2-CZ 2.79Å; D228-R345 IonicContact OD2-NH1 3.07Å; D228-R345 IonicContact OD2-NH2 3.58Å; D228-R345 PolarHBondContact OD2-NH2 2.86Å; D228-L364 HydrophobicContact CB-CD1 4.2Å
229V98.9Very high94.3Very high0 Ų035.7 Ų35.70%019%0.193CC..Hα-helixtrans-69.1-44.2175.8179.60000109.9D226 D227 H232 L233 L284 L362 L364D226-V229 WeakPolarHBondContact O-CB 3.07Å; D226-V229 PolarHBondContact O-N 3.48Å; D227-V229 VanDerWaalsContact C-N 3.3Å; D227-V229 PolarHBondContact O-N 3.08Å; V229-H232 WeakPolarHBondContact O-CB 3.24Å; V229-H232 PolarHBondContact O-N 3.14Å; V229-L233 HydrophobicContact CG1-CD1 3.88Å; V229-L233 HydrophobicContact CG1-CG 4.18Å; V229-L233 WeakPolarHBondContact O-CB 3.44Å; V229-L233 WeakPolarHBondContact O-CG 3.43Å; V229-L233 PolarHBondContact O-N 2.85Å; V229-L284 HydrophobicContact CB-CD2 4.4Å; V229-L284 HydrophobicContact CG1-CD2 3.79Å; V229-L362 HydrophobicContact CG1-CB 4.09Å; V229-L364 HydrophobicContact CG2-CG 4.15Å
230F98.9Very high96.2Very high0 Ų032.1 Ų32.10%017%0.17CC..Hα-helixtrans-61.3-45.3177.4-82.6-58.4000113Y206 P207 A224 D226 D227 H232 L233 A234 Y278 L284 L286Y206-F230 HydrophobicContact CD2-CB 4.04Å; Y206-F230 HydrophobicContact CG-CB 4.24Å; P207-F230 HydrophobicContact CB-CD2 4.45Å; P207-F230 HydrophobicContact CB-CE2 4.08Å; P207-F230 HydrophobicContact CB-CZ 4.11Å; P207-F230 HydrophobicContact CG-CD1 4.17Å; P207-F230 HydrophobicContact CG-CE1 3.65Å; P207-F230 HydrophobicContact CG-CE2 4.06Å; P207-F230 HydrophobicContact CG-CZ 3.58Å; A224-F230 HydrophobicContact CB-CD2 3.92Å; A224-F230 HydrophobicContact CB-CE2 3.92Å; D226-F230 HydrophobicContact CB-CD2 4.28Å; D226-F230 HydrophobicContact CB-CE2 4.22Å; D226-F230 WeakPolarHBondContact O-CD2 3.46Å; D226-F230 PolarHBondContact O-N 3.17Å; D227-F230 PolarHBondContact O-N 3.34Å; D227-F230 VanDerWaalsContact O-N 3.17Å; F230-H232 VanDerWaalsContact C-N 3.34Å; F230-H232 PolarHBondContact O-N 3.07Å; F230-L233 PolarHBondContact O-N 3.39Å; F230-A234 WeakPolarHBondContact O-CB 3.32Å; F230-A234 PolarHBondContact O-N 3.32Å; F230-Y278 HydrophobicContact CE2-CD1 4.17Å; F230-Y278 AromaticContact CE2-CD2 3.99Å; F230-Y278 HydrophobicContact CE2-CD2 3.99Å; F230-Y278 HydrophobicContact CE2-CE1 4.02Å; F230-Y278 AromaticContact CE2-CE2 3.84Å; F230-Y278 HydrophobicContact CE2-CE2 3.84Å; F230-Y278 HydrophobicContact CE2-CG 4.14Å; F230-Y278 AromaticContact CE2-CZ 3.84Å; F230-Y278 HydrophobicContact CZ-CD1 4.28Å; F230-Y278 AromaticContact CZ-CD2 3.74Å; F230-Y278 HydrophobicContact CZ-CD2 3.74Å; F230-Y278 HydrophobicContact CZ-CE2 4.05Å; F230-Y278 AromaticContact CZ-CG 3.86Å; F230-Y278 HydrophobicContact CZ-CG 3.86Å; F230-L284 HydrophobicContact CD1-CD2 4.45Å; F230-L284 HydrophobicContact CE1-CB 3.73Å; F230-L284 HydrophobicContact CE1-CD2 4.08Å; F230-L284 HydrophobicContact CE1-CG 3.86Å; F230-L284 HydrophobicContact CE2-CD2 4.32Å; F230-L284 HydrophobicContact CE2-CG 4.3Å; F230-L284 HydrophobicContact CZ-CB 3.97Å; F230-L284 HydrophobicContact CZ-CD2 4.01Å; F230-L284 HydrophobicContact CZ-CG 3.63Å; F230-L286 HydrophobicContact CD1-CD2 3.77Å; F230-L286 HydrophobicContact CE1-CD2 4.41Å
231V98.9Very high97.5Very high32 Ų3229.9 Ų29.919%0.19415%0.154CC..Hα-helixtrans-60.2-45174.8169.60000110.4Y206 D227 A234 K235 I260Y206-V231 HydrophobicContact CE1-CG2 4.17Å; Y206-V231 HydrophobicContact CE2-CG2 3.84Å; D227-V231 WeakPolarHBondContact O-CB 3.49Å; D227-V231 VanDerWaalsContact O-CG2 3.31Å; D227-V231 WeakPolarHBondContact O-CG2 3.5Å; D227-V231 PolarHBondContact O-N 3.01Å; V231-A234 PolarHBondContact O-N 3.1Å; V231-K235 HydrophobicContact CG1-CD 4.36Å; V231-K235 WeakPolarHBondContact O-CB 3.21Å; V231-K235 WeakPolarHBondContact O-CG 3.32Å; V231-K235 PolarHBondContact O-N 2.9Å; V231-I260 HydrophobicContact CG1-CD1 3.94Å
232H98.9Very high98Very high47 Ų4729.6 Ų29.622%0.21816%0.156CC..Hα-helixtrans-59.4-50174.9171.185.8000111.9D228 V229 F230 A234 K235 V236 Q318 L364D228-H232 WeakPolarHBondContact O-CB 3.32Å; D228-H232 PolarHBondContact O-N 3.1Å; V229-H232 WeakPolarHBondContact O-CB 3.24Å; V229-H232 PolarHBondContact O-N 3.14Å; F230-H232 VanDerWaalsContact C-N 3.34Å; F230-H232 PolarHBondContact O-N 3.07Å; H232-A234 VanDerWaalsContact C-N 3.32Å; H232-A234 PolarHBondContact O-N 2.54Å; H232-K235 PolarHBondContact O-N 3.21Å; H232-V236 WeakPolarHBondContact O-CG2 3.39Å; H232-V236 PolarHBondContact O-N 2.86Å; H232-Q318 PolarHBondContact NE2-OE1 3.21Å; H232-L364 HydrophobicContact CB-CD1 4.18Å; H232-L364 HydrophobicContact CB-CD2 3.64Å; H232-L364 HydrophobicContact CB-CG 4.49Å; H232-L364 VanDerWaalsContact CG-CD2 3.45Å
233L98.9Very high98.2Very high0 Ų030.2 Ų30.20%016%0.16CC..Hα-helixtrans-57.5-44.6178.8-73172.9000111.6L193 V229 F230 V236 Y237 L284 L286 Y315 Q318 L321L193-L233 HydrophobicContact CD1-CD1 3.67Å; L193-L233 HydrophobicContact CD1-CD2 3.97Å; L193-L233 HydrophobicContact CD1-CG 4.46Å; L193-L233 HydrophobicContact CD2-CD2 4.23Å; V229-L233 HydrophobicContact CG1-CD1 3.88Å; V229-L233 HydrophobicContact CG1-CG 4.18Å; V229-L233 WeakPolarHBondContact O-CB 3.44Å; V229-L233 WeakPolarHBondContact O-CG 3.43Å; V229-L233 PolarHBondContact O-N 2.85Å; F230-L233 PolarHBondContact O-N 3.39Å; L233-V236 PolarHBondContact O-N 2.93Å; L233-Y237 PolarHBondContact O-N 3.11Å; L233-L284 HydrophobicContact CD1-CB 4.41Å; L233-L284 HydrophobicContact CD1-CD2 4.14Å; L233-L286 HydrophobicContact CB-CD1 3.98Å; L233-Y315 HydrophobicContact CB-CE2 4.06Å; L233-Y315 HydrophobicContact CD2-CE2 4.28Å; L233-Q318 HydrophobicContact CD2-CB 3.39Å; L233-Q318 HydrophobicContact CD2-CG 3.89Å; L233-L321 HydrophobicContact CD2-CD1 4.15Å
234A98.9Very high98.4Very high0 Ų025.8 Ų25.80%014%0.138CC..Hα-helixtrans-65.1-42.8178.300000111.4A204 Y206 F230 V231 H232 Y237 S238 I260 L286A204-A234 HydrophobicContact CB-CB 3.91Å; Y206-A234 HydrophobicContact CD1-CB 3.95Å; F230-A234 WeakPolarHBondContact O-CB 3.32Å; F230-A234 PolarHBondContact O-N 3.32Å; V231-A234 PolarHBondContact O-N 3.1Å; H232-A234 VanDerWaalsContact C-N 3.32Å; H232-A234 PolarHBondContact O-N 2.54Å; A234-Y237 PolarHBondContact O-N 2.78Å; A234-S238 WeakPolarHBondContact O-CB 3.38Å; A234-S238 PolarHBondContact O-N 2.98Å; A234-I260 HydrophobicContact CB-CB 4.03Å; A234-I260 HydrophobicContact CB-CG2 3.58Å; A234-L286 HydrophobicContact CB-CD1 3.96Å
235K98.9Very high98.5Very high70 Ų7028.6 Ų28.630%0.30415%0.15SC..Hα-helixtrans-64.7-38.7174.9-71.7-169.2-173.6-1540112.1V231 H232 Y237 S238 Y239 D258 I260V231-K235 HydrophobicContact CG1-CD 4.36Å; V231-K235 WeakPolarHBondContact O-CB 3.21Å; V231-K235 WeakPolarHBondContact O-CG 3.32Å; V231-K235 PolarHBondContact O-N 2.9Å; H232-K235 PolarHBondContact O-N 3.21Å; K235-Y237 VanDerWaalsContact C-N 3.28Å; K235-Y237 PolarHBondContact O-N 3.36Å; K235-S238 PolarHBondContact O-N 2.77Å; K235-Y239 HydrophobicContact CB-CD2 3.96Å; K235-Y239 HydrophobicContact CB-CE2 4.18Å; K235-Y239 HydrophobicContact CD-CE2 4.15Å; K235-Y239 HydrophobicContact CG-CD2 4.37Å; K235-Y239 HydrophobicContact CG-CE2 4.11Å; K235-Y239 WeakPolarHBondContact O-CB 3.48Å; K235-Y239 WeakPolarHBondContact O-CD2 3.33Å; K235-Y239 PolarHBondContact O-N 2.73Å; K235-D258 WeakPolarHBondContact CE-OD2 3.31Å; K235-D258 IonicContact NZ-OD2 2.73Å; K235-D258 PolarHBondContact NZ-OD2 3.19Å; K235-I260 HydrophobicContact CD-CD1 4.44Å; K235-I260 HydrophobicContact CG-CD1 3.9Å; K235-I260 HydrophobicContact CG-CG2 4.15Å
236V98.9Very high98.4Very high17 Ų1733.2 Ų33.210%0.10317%0.166CC..Hα-helixtrans-56.7-45.4176.2167.30000110.5H232 L233 N240 A314 Q318H232-V236 WeakPolarHBondContact O-CG2 3.39Å; H232-V236 PolarHBondContact O-N 2.86Å; L233-V236 PolarHBondContact O-N 2.93Å; V236-N240 WeakPolarHBondContact O-CB 3.3Å; V236-N240 PolarHBondContact O-N 2.75Å; V236-N240 PolarHBondContact O-ND2 2.82Å; V236-A314 HydrophobicContact CG1-CB 4.13Å; V236-Q318 HydrophobicContact CB-CG 4.26Å; V236-Q318 HydrophobicContact CG1-CG 3.79Å; V236-Q318 HydrophobicContact CG2-CG 4.19Å
237Y98.9Very high98Very high0 Ų033.3 Ų33.30%017%0.168CC..Hα-helixtrans-66.4-54.3175.8-163.8-84.5000111.3L233 A234 K235 Y239 N240 H241 M244 L288 L290 N308 A311 L312 Y315L233-Y237 PolarHBondContact O-N 3.11Å; A234-Y237 PolarHBondContact O-N 2.78Å; K235-Y237 VanDerWaalsContact C-N 3.28Å; K235-Y237 PolarHBondContact O-N 3.36Å; Y237-Y239 PolarHBondContact O-N 3.28Å; Y237-N240 PolarHBondContact O-N 3.43Å; Y237-H241 PolarHBondContact O-N 2.91Å; Y237-M244 HydrophobicContact CD1-CE 4.08Å; Y237-M244 HydrophobicContact CD1-SD 3.95Å; Y237-M244 HydrophobicContact CE1-CE 3.9Å; Y237-M244 HydrophobicContact CE1-SD 4.38Å; Y237-L288 HydrophobicContact CD1-CD1 4.39Å; Y237-L288 HydrophobicContact CD1-CD2 3.93Å; Y237-L288 HydrophobicContact CD2-CD1 3.59Å; Y237-L288 HydrophobicContact CD2-CD2 4.15Å; Y237-L288 HydrophobicContact CE1-CD1 4.25Å; Y237-L288 HydrophobicContact CE1-CD2 4.39Å; Y237-L288 HydrophobicContact CE2-CD1 3.43Å; Y237-L288 VanDerWaalsContact CE2-CD1 3.43Å; Y237-L288 HydrophobicContact CG-CD1 4.08Å; Y237-L288 HydrophobicContact CG-CD2 3.8Å; Y237-L290 HydrophobicContact CE1-CD2 3.97Å; Y237-L290 VanDerWaalsContact OH-CD2 3.3Å; Y237-L290 WeakPolarHBondContact OH-CD2 3.16Å; Y237-N308 PolarHBondContact OH-OD1 3.26Å; Y237-A311 HydrophobicContact CD1-CB 4.07Å; Y237-A311 HydrophobicContact CD2-CB 3.82Å; Y237-A311 HydrophobicContact CE1-CB 3.94Å; Y237-A311 HydrophobicContact CE2-CB 3.68Å; Y237-A311 HydrophobicContact CG-CB 4.01Å; Y237-A311 WeakPolarHBondContact O-CB 3.47Å; Y237-L312 HydrophobicContact CE2-CD2 3.96Å; Y237-L312 HydrophobicContact CE2-CG 4.21Å; Y237-Y315 HydrophobicContact CD2-CD2 4.5Å; Y237-Y315 HydrophobicContact CD2-CG 4.32Å
238S98.8Very high97.3Very high0 Ų036.9 Ų36.90%019%0.187CC..Hα-helixtrans-58.6-42.6-173.5175.70000114.2A234 K235 H241 H245 D258 G259A234-S238 WeakPolarHBondContact O-CB 3.38Å; A234-S238 PolarHBondContact O-N 2.98Å; K235-S238 PolarHBondContact O-N 2.77Å; S238-H241 WeakPolarHBondContact O-CB 3.18Å; S238-H241 PolarHBondContact O-N 3.23Å; S238-H245 PolarHBondContact O-N 2.88Å; S238-H245 PolarHBondContact O-ND1 3.11Å; S238-H245 WeakPolarHBondContact OG-CA 3.38Å; S238-H245 PolarHBondContact OG-N 2.99Å; S238-H245 VanDerWaalsContact OG-N 3.08Å; S238-D258 WeakPolarHBondContact CB-O 3.47Å; S238-D258 PolarHBondContact OG-O 2.99Å; S238-G259 WeakPolarHBondContact OG-CA 3.24Å
239Y98.8Very high96.5Very high117 Ų11736.8 Ų36.846%0.45919%0.186SC..Hα-helixtrans-80.7-20.3179.7-79.4-87.5000113.8K235 Y237 H245 D258K235-Y239 HydrophobicContact CB-CD2 3.96Å; K235-Y239 HydrophobicContact CB-CE2 4.18Å; K235-Y239 HydrophobicContact CD-CE2 4.15Å; K235-Y239 HydrophobicContact CG-CD2 4.37Å; K235-Y239 HydrophobicContact CG-CE2 4.11Å; K235-Y239 WeakPolarHBondContact O-CB 3.48Å; K235-Y239 WeakPolarHBondContact O-CD2 3.33Å; K235-Y239 PolarHBondContact O-N 2.73Å; Y237-Y239 PolarHBondContact O-N 3.28Å; Y239-H245 HydrophobicContact CD1-CB 3.92Å; Y239-H245 HydrophobicContact CD2-CB 4.42Å; Y239-H245 HydrophobicContact CE1-CB 4.04Å; Y239-H245 HydrophobicContact CG-CB 4.13Å; Y239-D258 HydrophobicContact CE2-CB 3.96Å; Y239-D258 PolarHBondContact OH-OD1 2.62Å
240N98.8Very high96Very high43 Ų4337.2 Ų37.223%0.2319%0.189CC..Hα-helixtrans-87.6-16.7170.7-77.4-75.9000112.7V236 Y237 K310 A311 A314V236-N240 WeakPolarHBondContact O-CB 3.3Å; V236-N240 PolarHBondContact O-N 2.75Å; V236-N240 PolarHBondContact O-ND2 2.82Å; Y237-N240 PolarHBondContact O-N 3.43Å; N240-K310 HydrophobicContact CB-CD 4.41Å; N240-K310 HydrophobicContact CB-CG 4.32Å; N240-K310 WeakPolarHBondContact OD1-CE 3.48Å; N240-K310 PolarHBondContact OD1-NZ 2.79Å; N240-K310 VanDerWaalsContact OD1-NZ 3.12Å; N240-A311 HydrophobicContact CB-CB 4.07Å; N240-A314 HydrophobicContact CB-CB 4.26Å
241H98.8Very high95Very high4 Ų445.9 Ų45.92%0.01924%0.235CC..SBendtrans-69.5146.6166.5-171.5-97000110.3Y237 S238 S243 M244 D307 N308 A311Y237-H241 PolarHBondContact O-N 2.91Å; S238-H241 WeakPolarHBondContact O-CB 3.18Å; S238-H241 PolarHBondContact O-N 3.23Å; H241-S243 PolarHBondContact CE1-OG 2.84Å; H241-S243 PolarHBondContact ND1-N 2.83Å; H241-S243 PolarHBondContact O-N 2.85Å; H241-M244 HydrophobicContact CB-CB 3.75Å; H241-M244 WeakPolarHBondContact ND1-CB 3.31Å; H241-M244 PolarHBondContact ND1-N 3.21Å; H241-D307 WeakPolarHBondContact CA-O 3.23Å; H241-D307 PolarHBondContact CD2-O 2.94Å; H241-N308 VanDerWaalsContact CD2-CG 3.44Å; H241-N308 PolarHBondContact CD2-OD1 3.45Å; H241-N308 PolarHBondContact NE2-ND2 2.78Å; H241-N308 VanDerWaalsContact NE2-ND2 3.15Å; H241-N308 PolarHBondContact NE2-OD1 3.07Å; H241-A311 HydrophobicContact CB-CB 4.27Å
242A98.1Very high93.6Very high52 Ų5250 Ų5043%0.4326%0.257SS..SBendtrans-57.7-34.6-176.200000114.1D307A242-D307 HydrophobicContact CB-CB 3.75Å; A242-D307 WeakPolarHBondContact CB-OD1 3.46Å; A242-D307 PolarHBondContact N-O 3.31Å; A242-D307 VanDerWaalsContact N-O 3.16Å
243S96.9Very high92.1Very high20 Ų2048.5 Ų48.514%0.1425%0.251CS..SBendtrans-139.3-10.9-171.258.10000115.9H241 H245 K246 L249H241-S243 PolarHBondContact CE1-OG 2.84Å; H241-S243 PolarHBondContact ND1-N 2.83Å; H241-S243 PolarHBondContact O-N 2.85Å; S243-H245 VanDerWaalsContact C-N 3.3Å; S243-H245 PolarHBondContact O-N 2.95Å; S243-K246 WeakPolarHBondContact O-CB 3.42Å; S243-K246 VanDerWaalsContact O-CG 3.26Å; S243-K246 WeakPolarHBondContact O-CG 3.38Å; S243-K246 PolarHBondContact O-N 3.25Å; S243-L249 WeakPolarHBondContact O-CD1 3.44Å
244M97.9Very high90.6Very high0 Ų050.6 Ų50.60%027%0.273CS..G310 helixtrans-61-41.1-165.3-179.4178.2-73.100111.3M202 A204 Y237 H241 K246 G247 G259 E289M202-M244 HydrophobicContact CG-CB 4.38Å; M202-M244 HydrophobicContact CG-CE 4.2Å; M202-M244 HydrophobicContact CG-CG 4.33Å; A204-M244 HydrophobicContact CB-SD 4.15Å; Y237-M244 HydrophobicContact CD1-CE 4.08Å; Y237-M244 HydrophobicContact CD1-SD 3.95Å; Y237-M244 HydrophobicContact CE1-CE 3.9Å; Y237-M244 HydrophobicContact CE1-SD 4.38Å; H241-M244 HydrophobicContact CB-CB 3.75Å; H241-M244 WeakPolarHBondContact ND1-CB 3.31Å; H241-M244 PolarHBondContact ND1-N 3.21Å; M244-K246 PolarHBondContact O-N 3.09Å; M244-G247 PolarHBondContact O-N 3.14Å; M244-G259 WeakPolarHBondContact O-CA 3.41Å; M244-E289 VanDerWaalsContact CE-O 3.24Å; M244-E289 WeakPolarHBondContact CE-O 3.47Å
245H97.1Very high89.9Confident62 Ų6255.5 Ų55.529%0.28730%0.304SS..G310 helixtrans-56.4-15.6176.663.3-89.7000115.4S238 Y239 S243 G247S238-H245 PolarHBondContact O-N 2.88Å; S238-H245 PolarHBondContact O-ND1 3.11Å; S238-H245 WeakPolarHBondContact OG-CA 3.38Å; S238-H245 PolarHBondContact OG-N 2.99Å; S238-H245 VanDerWaalsContact OG-N 3.08Å; Y239-H245 HydrophobicContact CD1-CB 3.92Å; Y239-H245 HydrophobicContact CD2-CB 4.42Å; Y239-H245 HydrophobicContact CE1-CB 4.04Å; Y239-H245 HydrophobicContact CG-CB 4.13Å; S243-H245 VanDerWaalsContact C-N 3.3Å; S243-H245 PolarHBondContact O-N 2.95Å; H245-G247 VanDerWaalsContact C-N 3.27Å; H245-G247 PolarHBondContact O-N 2.97Å
246K95.6Very high89.7Confident134 Ų13452.8 Ų52.858%0.58329%0.293SS*.G310 helixtrans-70.9-23.2175.5-61.9176.4-177.3176.60112.6S243 M244 N248 L249S243-K246 WeakPolarHBondContact O-CB 3.42Å; S243-K246 VanDerWaalsContact O-CG 3.26Å; S243-K246 WeakPolarHBondContact O-CG 3.38Å; S243-K246 PolarHBondContact O-N 3.25Å; M244-K246 PolarHBondContact O-N 3.09Å; K246-N248 PolarHBondContact O-N 2.98Å; K246-L249 HydrophobicContact CB-CD1 4.5Å; K246-L249 HydrophobicContact CB-CD2 4.22Å; K246-L249 HydrophobicContact CB-CG 4.49Å; K246-L249 HydrophobicContact CD-CD2 4.35Å
247G89.6Confident89.5Confident3 Ų359.6 Ų59.63%0.03132%0.323CS..  trans75.1-17.2167.500000118.5M244 H245 F256M244-G247 PolarHBondContact O-N 3.14Å; H245-G247 VanDerWaalsContact C-N 3.27Å; H245-G247 PolarHBondContact O-N 2.97Å; G247-F256 WeakPolarHBondContact CA-O 3.35Å; G247-F256 PolarHBondContact O-N 3.09Å
248N83.3Confident89.4Confident113 Ų11361.5 Ų61.560%0.60433%0.334SS*.  trans-124.566.7-175.3-73.6-47.4000110.9K246 P255K246-N248 PolarHBondContact O-N 2.98Å; N248-P255 WeakPolarHBondContact OD1-CA 3.21Å; N248-P255 WeakPolarHBondContact OD1-CB 3.44Å
249L83.4Confident89.3Confident58 Ų5861.5 Ų61.530%0.30433%0.334SS..  trans-114.7-27.6-167.4-62.7164.1000113.7M202 S243 K246M202-L249 HydrophobicContact CB-CB 4.26Å; M202-L249 HydrophobicContact CB-CD1 4.25Å; M202-L249 HydrophobicContact CG-CD1 3.93Å; M202-L249 HydrophobicContact SD-CB 4.14Å; M202-L249 HydrophobicContact SD-CD1 3.23Å; M202-L249 WeakPolarHBondContact SD-CD1 3.44Å; M202-L249 HydrophobicContact SD-CG 4.22Å; S243-L249 WeakPolarHBondContact O-CD1 3.44Å; K246-L249 HydrophobicContact CB-CD1 4.5Å; K246-L249 HydrophobicContact CB-CD2 4.22Å; K246-L249 HydrophobicContact CB-CG 4.49Å; K246-L249 HydrophobicContact CD-CD2 4.35Å
250C87.7Confident89.3Confident10 Ų1056.9 Ų56.97%0.06832%0.316CS..SBendtrans-111.9135.9175.5-41.70000109D252 S253 C292C250-D252 PolarHBondContact O-N 3.05Å; C250-S253 WeakPolarHBondContact CB-OG 3.45Å; C250-S253 PolarHBondContact O-N 2.85Å; C250-S253 PolarHBondContact O-OG 2.82Å; C250-C292 WeakPolarHBondContact CA-SG 3.26Å; C250-C292 HydrophobicContact CB-CB 3.66Å; C250-C292 WeakPolarHBondContact CB-SG 3.37Å; C250-C292 WeakPolarHBondContact SG-CA 3.27Å; C250-C292 WeakPolarHBondContact SG-CB 3.29Å; C250-C292 CovalentContact SG-SG 2.03Å; C250-C292 PolarHBondContact SG-SG 3.35Å
251D76.9Confident89.2Confident182 Ų18255.6 Ų55.697%0.97331%0.31SS*.THydrogen-bonded Turntrans-65.4-22.8-172.7-66.9-34.5000113.5
252D69.9Low89.2Confident119 Ų11955.6 Ų55.664%0.63631%0.31SS*.THydrogen-bonded Turntrans-107.2-4.4-173.660.8-18.4000114.2C250C250-D252 PolarHBondContact O-N 3.05Å
253S67.4Low89.1Confident15 Ų1553.2 Ų53.211%0.10529%0.291CS..SBendtrans-107.4121174.7730000109.1C250C250-S253 WeakPolarHBondContact CB-OG 3.45Å; C250-S253 PolarHBondContact O-N 2.85Å; C250-S253 PolarHBondContact O-OG 2.82Å
254G67.2Low88.9Confident44 Ų4453.8 Ų53.845%0.45429%0.29SS..  trans-56.2169.9-17900000113.7F256G254-F256 WeakPolarHBondContact O-CD2 3.49Å; G254-F256 PolarHBondContact O-N 3.46Å; G254-F256 VanDerWaalsContact O-N 3.07Å
255P85.7Confident88.7Confident102 Ų10255.7 Ų55.766%0.66230%0.304SS*.  trans-59.3114.3-179.222.4-32.7000112.1N248N248-P255 WeakPolarHBondContact OD1-CA 3.21Å; N248-P255 WeakPolarHBondContact OD1-CB 3.44Å
256F93.6Very high88.5Confident14 Ų1456.4 Ų56.46%0.06130%0.304CS..  trans-93.195.2170.7-58.6-61.6000109.7V203 G247 G254 D258 G259 T261 W266V203-F256 HydrophobicContact CB-CB 4.36Å; V203-F256 HydrophobicContact CB-CD1 4.34Å; V203-F256 HydrophobicContact CB-CD2 3.58Å; V203-F256 HydrophobicContact CB-CE2 3.8Å; V203-F256 HydrophobicContact CB-CG 3.85Å; V203-F256 HydrophobicContact CB-CZ 4.29Å; V203-F256 HydrophobicContact CG1-CD2 4.12Å; V203-F256 HydrophobicContact CG1-CE1 4.39Å; V203-F256 HydrophobicContact CG1-CE2 3.79Å; V203-F256 HydrophobicContact CG1-CZ 3.94Å; V203-F256 HydrophobicContact CG2-CB 3.8Å; V203-F256 HydrophobicContact CG2-CD1 3.78Å; V203-F256 HydrophobicContact CG2-CD2 3.84Å; V203-F256 HydrophobicContact CG2-CE1 4.27Å; V203-F256 HydrophobicContact CG2-CE2 4.3Å; V203-F256 HydrophobicContact CG2-CG 3.54Å; V203-F256 HydrophobicContact CG2-CZ 4.5Å; G247-F256 WeakPolarHBondContact CA-O 3.35Å; G247-F256 PolarHBondContact O-N 3.09Å; G254-F256 WeakPolarHBondContact O-CD2 3.49Å; G254-F256 PolarHBondContact O-N 3.46Å; G254-F256 VanDerWaalsContact O-N 3.07Å; F256-D258 PolarHBondContact O-N 3.5Å; F256-G259 WeakPolarHBondContact O-CA 3.47Å; F256-G259 PolarHBondContact O-N 3.34Å; F256-T261 HydrophobicContact CD1-CG2 4.26Å; F256-T261 HydrophobicContact CE1-CG2 4.14Å; F256-W266 AromaticContact CE1-CD1 3.98Å; F256-W266 HydrophobicContact CE1-CD2 4.22Å; F256-W266 HydrophobicContact CE1-CG 4.04Å; F256-W266 HydrophobicContact CZ-CD2 4.14Å; F256-W266 AromaticContact CZ-CE2 3.81Å; F256-W266 HydrophobicContact CZ-CG 4.33Å; F256-W266 HydrophobicContact CZ-CZ2 4.24Å; F256-W266 AromaticContact CZ-NE1 3.78Å
257Q94.5Very high88.2Confident159 Ų15954 Ų5474%0.74329%0.292SS*.G310 helixtrans-54.4132177.1-175174.23.500110.5G259 I260Q257-G259 PolarHBondContact O-N 3.42Å; Q257-G259 VanDerWaalsContact O-N 3.09Å; Q257-I260 PolarHBondContact O-N 2.89Å
258D97.2Very high88.3Confident41 Ų4158.5 Ų58.522%0.21931%0.311CS..G310 helixtrans57.815.2-174.3-55.8-23000114.5K235 S238 Y239 F256 I260K235-D258 WeakPolarHBondContact CE-OD2 3.31Å; K235-D258 IonicContact NZ-OD2 2.73Å; K235-D258 PolarHBondContact NZ-OD2 3.19Å; S238-D258 WeakPolarHBondContact CB-O 3.47Å; S238-D258 PolarHBondContact OG-O 2.99Å; Y239-D258 HydrophobicContact CE2-CB 3.96Å; Y239-D258 PolarHBondContact OH-OD1 2.62Å; F256-D258 PolarHBondContact O-N 3.5Å; D258-I260 VanDerWaalsContact C-N 3.27Å; D258-I260 HydrophobicContact CB-CG1 4.4Å; D258-I260 PolarHBondContact O-N 2.82Å
259G97.6Very high88.8Confident0 Ų053.3 Ų53.30%028%0.283CS..G310 helixtrans6527.1-178.100000114.2A204 S238 M244 F256 Q257A204-G259 PolarHBondContact N-O 3.17Å; S238-G259 WeakPolarHBondContact OG-CA 3.24Å; M244-G259 WeakPolarHBondContact O-CA 3.41Å; F256-G259 WeakPolarHBondContact O-CA 3.47Å; F256-G259 PolarHBondContact O-N 3.34Å; Q257-G259 PolarHBondContact O-N 3.42Å; Q257-G259 VanDerWaalsContact O-N 3.09Å
260I98.1Very high89.2Confident19 Ų1953.7 Ų53.710%0.09728%0.283CS..EExtended strand (participates in β ladder)trans-128.4158.2178.367.8166.8000111.1A204 Y206 V231 A234 K235 Q257 D258A204-I260 HydrophobicContact CB-CG2 4.33Å; A204-I260 VanDerWaalsContact O-CA 3.29Å; A204-I260 WeakPolarHBondContact O-CA 3.41Å; Y206-I260 HydrophobicContact CE1-CB 4.25Å; Y206-I260 HydrophobicContact CE1-CD1 4.01Å; Y206-I260 HydrophobicContact CE1-CG1 4.31Å; V231-I260 HydrophobicContact CG1-CD1 3.94Å; A234-I260 HydrophobicContact CB-CB 4.03Å; A234-I260 HydrophobicContact CB-CG2 3.58Å; K235-I260 HydrophobicContact CD-CD1 4.44Å; K235-I260 HydrophobicContact CG-CD1 3.9Å; K235-I260 HydrophobicContact CG-CG2 4.15Å; Q257-I260 PolarHBondContact O-N 2.89Å; D258-I260 VanDerWaalsContact C-N 3.27Å; D258-I260 HydrophobicContact CB-CG1 4.4Å; D258-I260 PolarHBondContact O-N 2.82Å
261T97.1Very high89.4Confident17 Ų1753.4 Ų53.410%0.10428%0.282CS..EExtended strand (participates in β ladder)trans-152.1146171-170.90000112V203 A204 S205 Y206 F256 W266V203-T261 HydrophobicContact CG1-CG2 4.35Å; V203-T261 HydrophobicContact CG2-CG2 3.7Å; A204-T261 PolarHBondContact O-N 3.35Å; S205-T261 CarbonylContact C-O 3.51Å; S205-T261 VanDerWaalsContact CA-O 3.28Å; S205-T261 WeakPolarHBondContact CA-O 3.04Å; Y206-T261 VanDerWaalsContact CD1-C 3.49Å; Y206-T261 WeakPolarHBondContact CD1-O 3.44Å; Y206-T261 WeakPolarHBondContact CE1-O 3.36Å; Y206-T261 PolarHBondContact N-O 2.83Å; F256-T261 HydrophobicContact CD1-CG2 4.26Å; F256-T261 HydrophobicContact CE1-CG2 4.14Å; T261-W266 HydrophobicContact CG2-CB 3.9Å; T261-W266 HydrophobicContact CG2-CD2 4.32Å; T261-W266 HydrophobicContact CG2-CE3 4Å; T261-W266 HydrophobicContact CG2-CG 4.33Å
262N97.6Very high90.4Very high3 Ų344.8 Ų44.82%0.01624%0.236CC..EExtended strand (participates in β ladder)trans-67.2136159.5174.3-102.1000107.9Y206 P207 Y208 P221 S222 Y264 S265 W266Y206-N262 HydrophobicContact CD2-CB 4.43Å; Y206-N262 HydrophobicContact CE2-CB 3.77Å; P207-N262 PolarHBondContact O-ND2 2.93Å; P207-N262 VanDerWaalsContact O-ND2 3.08Å; Y208-N262 PolarHBondContact N-ND2 3.21Å; P221-N262 HydrophobicContact CB-CB 4.19Å; S222-N262 PolarHBondContact N-OD1 2.73Å; S222-N262 VanDerWaalsContact N-OD1 3.1Å; S222-N262 PolarHBondContact O-ND2 2.94Å; N262-Y264 PolarHBondContact O-N 3.48Å; N262-Y264 PolarHBondContact OD1-N 3.48Å; N262-S265 PolarHBondContact O-N 3.48Å; N262-S265 PolarHBondContact OD1-N 3.16Å; N262-S265 VanDerWaalsContact OD1-N 3.13Å; N262-S265 PolarHBondContact OD1-OG 2.69Å; N262-W266 PolarHBondContact O-N 2.81Å; N262-W266 VanDerWaalsContact O-N 3.12Å
263G96.3Very high91.8Very high3 Ų339.1 Ų39.13%0.03121%0.206CC..Hα-helixtrans-57.5-51.3-175.700000112.2S205 Y206 D209 S265 W266 Y267S205-G263 WeakPolarHBondContact OG-CA 3.28Å; Y206-G263 PolarHBondContact O-N 2.84Å; D209-G263 WeakPolarHBondContact OD1-CA 3.41Å; G263-S265 VanDerWaalsContact C-N 3.34Å; G263-S265 PolarHBondContact O-N 3.12Å; G263-W266 WeakPolarHBondContact O-CB 3.14Å; G263-W266 PolarHBondContact O-N 3.16Å; G263-Y267 PolarHBondContact O-N 3.19Å
264Y94.1Very high93.3Very high31 Ų3138.4 Ų38.412%0.12220%0.201CC..Hα-helixtrans-63.9-35.9179.4-169.5-105.8000113.3Y208 S211 S220 N262 W266 K268Y208-Y264 WeakPolarHBondContact O-CB 3.49Å; Y208-Y264 PolarHBondContact O-N 3.18Å; S211-Y264 VanDerWaalsContact CB-CZ 3.45Å; S220-Y264 WeakPolarHBondContact O-CD1 3.25Å; N262-Y264 PolarHBondContact O-N 3.48Å; N262-Y264 PolarHBondContact OD1-N 3.48Å; Y264-W266 VanDerWaalsContact C-N 3.26Å; Y264-W266 PolarHBondContact O-N 3.15Å; Y264-K268 HydrophobicContact CD2-CB 4.07Å; Y264-K268 HydrophobicContact CD2-CG 4.21Å; Y264-K268 HydrophobicContact CE2-CB 3.75Å; Y264-K268 HydrophobicContact CE2-CD 4.27Å; Y264-K268 HydrophobicContact CE2-CG 3.77Å
265S92.2Very high94.7Very high41 Ų4136.6 Ų36.629%0.28718%0.181SC..Hα-helixtrans-63.4-31173.4-70.20000113.4P221 N262 G263P221-S265 VanDerWaalsContact CA-OG 3.26Å; P221-S265 WeakPolarHBondContact CA-OG 3.4Å; P221-S265 WeakPolarHBondContact CB-OG 3.36Å; N262-S265 PolarHBondContact O-N 3.48Å; N262-S265 PolarHBondContact OD1-N 3.16Å; N262-S265 VanDerWaalsContact OD1-N 3.13Å; N262-S265 PolarHBondContact OD1-OG 2.69Å; G263-S265 VanDerWaalsContact C-N 3.34Å; G263-S265 PolarHBondContact O-N 3.12Å
266W92.9Very high95.2Very high76 Ų7632 Ų3229%0.28815%0.15SC..Hα-helixtrans-76.2-57.8175-179.418.4000110.5A201 V203 F256 T261 N262 G263 Y264 E289A201-W266 HydrophobicContact CB-CH2 3.77Å; A201-W266 HydrophobicContact CB-CZ2 3.87Å; V203-W266 HydrophobicContact CG1-CE3 4.42Å; V203-W266 HydrophobicContact CG1-CH2 4.3Å; V203-W266 HydrophobicContact CG1-CZ3 4.07Å; F256-W266 AromaticContact CE1-CD1 3.98Å; F256-W266 HydrophobicContact CE1-CD2 4.22Å; F256-W266 HydrophobicContact CE1-CG 4.04Å; F256-W266 HydrophobicContact CZ-CD2 4.14Å; F256-W266 AromaticContact CZ-CE2 3.81Å; F256-W266 HydrophobicContact CZ-CG 4.33Å; F256-W266 HydrophobicContact CZ-CZ2 4.24Å; F256-W266 AromaticContact CZ-NE1 3.78Å; T261-W266 HydrophobicContact CG2-CB 3.9Å; T261-W266 HydrophobicContact CG2-CD2 4.32Å; T261-W266 HydrophobicContact CG2-CE3 4Å; T261-W266 HydrophobicContact CG2-CG 4.33Å; N262-W266 PolarHBondContact O-N 2.81Å; N262-W266 VanDerWaalsContact O-N 3.12Å; G263-W266 WeakPolarHBondContact O-CB 3.14Å; G263-W266 PolarHBondContact O-N 3.16Å; Y264-W266 VanDerWaalsContact C-N 3.26Å; Y264-W266 PolarHBondContact O-N 3.15Å; W266-E289 HydrophobicContact CH2-CG 3.89Å; W266-E289 HydrophobicContact CZ3-CG 3.98Å
267Y90.3Very high95.5Very high83 Ų8331.3 Ų31.333%0.32515%0.147SC..  trans-163.2150.8169.764-87.7000111G263 L269G263-Y267 PolarHBondContact O-N 3.19Å; Y267-L269 HydrophobicContact CD2-CB 4.28Å; Y267-L269 HydrophobicContact CE2-CB 3.86Å; Y267-L269 HydrophobicContact CE2-CD1 3.96Å; Y267-L269 HydrophobicContact CE2-CG 4.36Å; Y267-L269 PolarHBondContact O-N 2.74Å
268K91.9Very high95.6Very high98 Ų9823.9 Ų23.943%0.42611%0.112SC..  trans-63.5124.5174.7179.5-175.9179.2-144.50110.9N210 Y264 E270N210-K268 WeakPolarHBondContact OD1-CE 3.21Å; Y264-K268 HydrophobicContact CD2-CB 4.07Å; Y264-K268 HydrophobicContact CD2-CG 4.21Å; Y264-K268 HydrophobicContact CE2-CB 3.75Å; Y264-K268 HydrophobicContact CE2-CD 4.27Å; Y264-K268 HydrophobicContact CE2-CG 3.77Å; K268-E270 IonicContact NZ-OE2 2.94Å; K268-E270 PolarHBondContact NZ-OE2 3.08Å
269L92.6Very high95.5Very high5 Ų522.3 Ų22.33%0.02610%0.104CC..  trans-127.8114.4174.7178.9161.8000110R155 D209 N210 Y267R155-L269 VanDerWaalsContact CZ-CG 3.4Å; R155-L269 VanDerWaalsContact NH1-CG 3.29Å; D209-L269 CarbonylContact C-O 3.48Å; D209-L269 HydrophobicContact CB-CB 4.03Å; D209-L269 HydrophobicContact CB-CD2 4.02Å; D209-L269 HydrophobicContact CB-CG 4.45Å; D209-L269 PolarHBondContact O-N 2.63Å; N210-L269 WeakPolarHBondContact CB-O 3.12Å; Y267-L269 HydrophobicContact CD2-CB 4.28Å; Y267-L269 HydrophobicContact CE2-CB 3.86Å; Y267-L269 HydrophobicContact CE2-CD1 3.96Å; Y267-L269 HydrophobicContact CE2-CG 4.36Å; Y267-L269 PolarHBondContact O-N 2.74Å
270E92.2Very high95.4Very high66 Ų6624.7 Ų24.731%0.30811%0.113SC..SBendtrans-98.4133.4180-175.8170.9146.100110.5R155 D159 A162 K268R155-E270 WeakPolarHBondContact CD-O 3.21Å; D159-E270 HydrophobicContact CB-CG 4.14Å; D159-E270 WeakPolarHBondContact OD2-CA 3.44Å; A162-E270 HydrophobicContact CB-CG 4.03Å; A162-E270 WeakPolarHBondContact CB-OE1 3.42Å; K268-E270 IonicContact NZ-OE2 2.94Å; K268-E270 PolarHBondContact NZ-OE2 3.08Å
271G93.2Very high95.3Very high3 Ų324.7 Ų24.73%0.03112%0.116CC..SBendtrans77.531.917600000114.8N154 R155 G156 F157 D159N154-G271 CarbonylContact C-O 3.49Å; R155-G271 CarbonylContact C-O 3.54Å; R155-G271 WeakPolarHBondContact CA-O 3.44Å; G156-G271 PolarHBondContact N-O 2.71Å; F157-G271 WeakPolarHBondContact CB-O 3.21Å; F157-G271 PolarHBondContact N-O 3.29Å; F157-G271 VanDerWaalsContact O-CA 3.27Å; F157-G271 WeakPolarHBondContact O-CA 3.3Å; D159-G271 PolarHBondContact OD2-N 3.29Å
272G96.9Very high95.2Very high2 Ų226.3 Ų26.32%0.02112%0.123CC..  trans-77.7151.5178.100000114.1N154 Q274 Y276N154-G272 VanDerWaalsContact OD1-CA 3.31Å; N154-G272 WeakPolarHBondContact OD1-CA 3.37Å; G272-Q274 VanDerWaalsContact C-N 3.32Å; G272-Y276 PolarHBondContact O-N 2.75Å
273M98.6Very high95.3Very high0 Ų026.2 Ų26.20%012%0.122CC..Hα-helixtrans-66.5-35.2175.7-172.9169.162.700112.1V80 M83 M127 N154 F157 V182 N196 Y276 N277V80-M273 HydrophobicContact CB-CE 4.16Å; V80-M273 HydrophobicContact CG1-CE 3.96Å; M83-M273 HydrophobicContact CE-CB 4.2Å; M83-M273 HydrophobicContact CE-CE 4.29Å; M83-M273 HydrophobicContact SD-CE 3.94Å; M127-M273 HydrophobicContact CE-SD 4.48Å; M127-M273 HydrophobicContact SD-CE 4.47Å; M127-M273 HydrophobicContact SD-SD 3.95Å; N154-M273 PolarHBondContact OD1-N 3.32Å; F157-M273 HydrophobicContact CD1-CG 4.47Å; F157-M273 HydrophobicContact CD2-CB 3.8Å; F157-M273 HydrophobicContact CD2-CG 4.39Å; F157-M273 HydrophobicContact CE1-CB 4.32Å; F157-M273 HydrophobicContact CE1-CG 3.87Å; F157-M273 HydrophobicContact CE1-SD 4.43Å; F157-M273 HydrophobicContact CE2-CB 3.53Å; F157-M273 HydrophobicContact CE2-CG 3.8Å; F157-M273 HydrophobicContact CE2-SD 4.09Å; F157-M273 HydrophobicContact CG-CB 4.32Å; F157-M273 HydrophobicContact CZ-CB 3.81Å; F157-M273 HydrophobicContact CZ-CG 3.5Å; F157-M273 VanDerWaalsContact CZ-CG 3.5Å; F157-M273 HydrophobicContact CZ-SD 3.65Å; V182-M273 HydrophobicContact CG1-SD 3.85Å; N196-M273 HydrophobicContact CB-CE 3.32Å; M273-Y276 PolarHBondContact O-N 2.93Å; M273-N277 PolarHBondContact O-N 2.97Å; M273-N277 PolarHBondContact O-ND2 2.88Å
274Q98.7Very high95.4Very high0 Ų026.2 Ų26.20%012%0.121CC..Hα-helixtrans-59.2-54.3-177.1-170.6-168.3-99.200112S205 P207 D209 G272 Y276 N277 Y278 E285 T287S205-Q274 PolarHBondContact O-OE1 3.47Å; S205-Q274 VanDerWaalsContact O-OE1 3.11Å; P207-Q274 HydrophobicContact CG-CG 3.83Å; D209-Q274 PolarHBondContact OD1-NE2 2.83Å; D209-Q274 PolarHBondContact OD2-NE2 2.77Å; D209-Q274 VanDerWaalsContact OD2-NE2 3.16Å; G272-Q274 VanDerWaalsContact C-N 3.32Å; Q274-Y276 VanDerWaalsContact C-N 3.29Å; Q274-Y276 PolarHBondContact O-N 2.85Å; Q274-N277 WeakPolarHBondContact O-CB 3.35Å; Q274-N277 PolarHBondContact O-N 2.96Å; Q274-Y278 PolarHBondContact O-N 3.06Å; Q274-E285 HydrophobicContact CG-CB 4.37Å; Q274-E285 HydrophobicContact CG-CG 4.48Å; Q274-E285 WeakPolarHBondContact CG-O 3.48Å; Q274-T287 VanDerWaalsContact OE1-CB 3.25Å; Q274-T287 PolarHBondContact OE1-OG1 3.41Å
275D97.6Very high95.6Very high5 Ų524.7 Ų24.73%0.02712%0.116CC..Hα-helixtrans-65.9-33.9178.4-75.42.8000111.4Y208 D209 N210 N277 Y278 V279Y208-D275 WeakPolarHBondContact CA-OD1 3.48Å; Y208-D275 HydrophobicContact CD1-CB 4.41Å; D209-D275 PolarHBondContact N-OD1 2.8Å; D209-D275 VanDerWaalsContact N-OD1 3.07Å; D209-D275 PolarHBondContact N-OD2 2.93Å; N210-D275 PolarHBondContact N-OD2 3.49Å; D275-N277 PolarHBondContact O-N 2.66Å; D275-Y278 PolarHBondContact O-N 2.69Å; D275-V279 WeakPolarHBondContact O-CB 3.28Å; D275-V279 WeakPolarHBondContact O-CG2 3.47Å; D275-V279 PolarHBondContact O-N 2.94Å
276Y96.9Very high95.9Very high5 Ų522.8 Ų22.82%0.0210%0.102CC..Hα-helixtrans-61.3-44.4177.2-177.8-91.7000112.5F157 P158 E172 I183 L186 G272 M273 Q274 Y278 W280 A281F157-Y276 HydrophobicContact CB-CG 4.38Å; F157-Y276 AromaticContact CD1-CD1 3.87Å; F157-Y276 HydrophobicContact CD1-CD1 3.87Å; F157-Y276 HydrophobicContact CD1-CD2 4.34Å; F157-Y276 AromaticContact CD1-CG 3.76Å; F157-Y276 HydrophobicContact CD1-CG 3.76Å; F157-Y276 HydrophobicContact CE1-CD1 4.31Å; F157-Y276 HydrophobicContact CG-CG 4.49Å; P158-Y276 HydrophobicContact CB-CD2 3.91Å; P158-Y276 HydrophobicContact CB-CE2 3.94Å; P158-Y276 HydrophobicContact CG-CD2 3.77Å; P158-Y276 HydrophobicContact CG-CE2 3.48Å; P158-Y276 VanDerWaalsContact CG-CE2 3.48Å; E172-Y276 PolarHBondContact OE1-OH 3.33Å; I183-Y276 HydrophobicContact CD1-CE2 4.44Å; I183-Y276 HydrophobicContact CG1-CE1 3.8Å; I183-Y276 WeakPolarHBondContact CG2-OH 3.1Å; L186-Y276 HydrophobicContact CD1-CD1 3.66Å; L186-Y276 HydrophobicContact CD1-CE1 3.64Å; G272-Y276 PolarHBondContact O-N 2.75Å; M273-Y276 PolarHBondContact O-N 2.93Å; Q274-Y276 VanDerWaalsContact C-N 3.29Å; Q274-Y276 PolarHBondContact O-N 2.85Å; Y276-Y278 VanDerWaalsContact C-N 3.3Å; Y276-Y278 PolarHBondContact O-N 3.03Å; Y276-W280 HydrophobicContact CD2-CB 4.47Å; Y276-W280 AromaticContact CD2-CD2 3.94Å; Y276-W280 HydrophobicContact CD2-CD2 3.94Å; Y276-W280 AromaticContact CD2-CE3 3.15Å; Y276-W280 HydrophobicContact CD2-CE3 3.15Å; Y276-W280 AromaticContact CD2-CZ3 3.56Å; Y276-W280 HydrophobicContact CD2-CZ3 3.56Å; Y276-W280 HydrophobicContact CE2-CB 4.04Å; Y276-W280 AromaticContact CE2-CD2 3.92Å; Y276-W280 HydrophobicContact CE2-CD2 3.92Å; Y276-W280 AromaticContact CE2-CE3 3.62Å; Y276-W280 HydrophobicContact CE2-CE3 3.62Å; Y276-W280 HydrophobicContact CE2-CG 4.13Å; Y276-W280 HydrophobicContact CE2-CZ3 4.28Å; Y276-W280 AromaticContact CG-CE3 3.87Å; Y276-W280 HydrophobicContact CG-CE3 3.87Å; Y276-W280 HydrophobicContact CG-CZ3 4.34Å; Y276-W280 PolarHBondContact O-N 2.96Å; Y276-A281 PolarHBondContact O-N 3.39Å
277N98.6Very high96.2Very high0 Ų019.5 Ų19.50%09%0.091CC..Hα-helixtrans-55.9-46.8177.3-87.8-97.9000111.5K78 L186 M273 Q274 D275 A281 Q282 C283 E285K78-N277 VanDerWaalsContact CE-OD1 3.32Å; K78-N277 WeakPolarHBondContact CE-OD1 3.44Å; K78-N277 PolarHBondContact NZ-OD1 2.02Å; L186-N277 VanDerWaalsContact CD2-OD1 3.24Å; L186-N277 WeakPolarHBondContact CD2-OD1 3.42Å; M273-N277 PolarHBondContact O-N 2.97Å; M273-N277 PolarHBondContact O-ND2 2.88Å; Q274-N277 WeakPolarHBondContact O-CB 3.35Å; Q274-N277 PolarHBondContact O-N 2.96Å; D275-N277 PolarHBondContact O-N 2.66Å; N277-A281 CarbonylContact O-C 3.58Å; N277-A281 VanDerWaalsContact O-C 3.29Å; N277-A281 WeakPolarHBondContact O-CA 3.4Å; N277-A281 WeakPolarHBondContact O-CB 3.5Å; N277-A281 PolarHBondContact O-N 3.31Å; N277-A281 VanDerWaalsContact O-N 3.1Å; N277-Q282 PolarHBondContact O-N 3.18Å; N277-C283 CarbonylContact C-O 3.08Å; N277-C283 HydrophobicContact CB-CB 4.26Å; N277-C283 WeakPolarHBondContact CB-O 3.21Å; N277-C283 PolarHBondContact O-N 3.45Å; N277-E285 HydrophobicContact CB-CB 3.72Å; N277-E285 VanDerWaalsContact ND2-CD 3.26Å; N277-E285 PolarHBondContact ND2-OE1 3.26Å; N277-E285 PolarHBondContact ND2-OE2 3.11Å; N277-E285 VanDerWaalsContact ND2-OE2 3.1Å; N277-E285 PolarHBondContact OD1-OE2 3.36Å
278Y98Very high96.6Very high3 Ų315.6 Ų15.61%0.0128%0.075CC..Hα-helixtrans-74.5-41.8-175.1178.8-124.4000112.5Y208 A224 P225 D226 F230 Q274 D275 Y276 C283 L284 N347 F351Y208-Y278 HydrophobicContact CD1-CD1 4.5Å; Y208-Y278 AromaticContact CE1-CD1 3.6Å; Y208-Y278 HydrophobicContact CE1-CD1 3.6Å; Y208-Y278 AromaticContact CE1-CE1 3.9Å; Y208-Y278 HydrophobicContact CE1-CE1 3.9Å; Y208-Y278 AromaticContact CZ-CD1 3.9Å; Y208-Y278 AromaticContact CZ-CE1 3.68Å; Y208-Y278 WeakPolarHBondContact OH-CE1 3.36Å; A224-Y278 HydrophobicContact CB-CE1 3.81Å; P225-Y278 WeakPolarHBondContact CD-OH 3.34Å; D226-Y278 HydrophobicContact CB-CE2 4.18Å; D226-Y278 WeakPolarHBondContact CB-OH 3.3Å; D226-Y278 PolarHBondContact N-OH 2.78Å; D226-Y278 PolarHBondContact OD2-OH 3.14Å; F230-Y278 HydrophobicContact CE2-CD1 4.17Å; F230-Y278 AromaticContact CE2-CD2 3.99Å; F230-Y278 HydrophobicContact CE2-CD2 3.99Å; F230-Y278 HydrophobicContact CE2-CE1 4.02Å; F230-Y278 AromaticContact CE2-CE2 3.84Å; F230-Y278 HydrophobicContact CE2-CE2 3.84Å; F230-Y278 HydrophobicContact CE2-CG 4.14Å; F230-Y278 AromaticContact CE2-CZ 3.84Å; F230-Y278 HydrophobicContact CZ-CD1 4.28Å; F230-Y278 AromaticContact CZ-CD2 3.74Å; F230-Y278 HydrophobicContact CZ-CD2 3.74Å; F230-Y278 HydrophobicContact CZ-CE2 4.05Å; F230-Y278 AromaticContact CZ-CG 3.86Å; F230-Y278 HydrophobicContact CZ-CG 3.86Å; Q274-Y278 PolarHBondContact O-N 3.06Å; D275-Y278 PolarHBondContact O-N 2.69Å; Y276-Y278 VanDerWaalsContact C-N 3.3Å; Y276-Y278 PolarHBondContact O-N 3.03Å; Y278-C283 VanDerWaalsContact CA-O 3.26Å; Y278-C283 WeakPolarHBondContact CA-O 3.45Å; Y278-C283 PolarHBondContact N-O 2.84Å; Y278-L284 HydrophobicContact CD2-CD1 4.16Å; Y278-L284 HydrophobicContact CD2-CG 4.12Å; Y278-L284 HydrophobicContact CE2-CD1 4.27Å; Y278-L284 HydrophobicContact CE2-CG 4.3Å; Y278-N347 VanDerWaalsContact CZ-ND2 3.3Å; Y278-N347 PolarHBondContact OH-ND2 3.41Å; Y278-F351 HydrophobicContact CE2-CE2 4.48Å; Y278-F351 HydrophobicContact CE2-CZ 4.45Å
279V95.1Very high96.9Very high8 Ų811.5 Ų11.55%0.0486%0.058CC..Hα-helixtrans-73.9-52.2-178.2176.40000111.3A160 Y208 D275 M348 C349A160-V279 HydrophobicContact CB-CG1 4.13Å; A160-V279 HydrophobicContact CB-CG2 4.07Å; Y208-V279 HydrophobicContact CE1-CG2 3.95Å; D275-V279 WeakPolarHBondContact O-CB 3.28Å; D275-V279 WeakPolarHBondContact O-CG2 3.47Å; D275-V279 PolarHBondContact O-N 2.94Å; V279-M348 HydrophobicContact CG1-CB 4.33Å; V279-M348 HydrophobicContact CG2-SD 4.05Å; V279-C349 HydrophobicContact CG1-CB 4.36Å; V279-C349 WeakPolarHBondContact O-CB 3.21Å
280W93.9Very high97.2Very high50 Ų5011.3 Ų11.319%0.1896%0.056CC..Hα-helixtrans-105-27.7-170.8-66.8-82000114.8P158 A160 Y276P158-W280 HydrophobicContact CB-CH2 3.94Å; P158-W280 HydrophobicContact CB-CZ2 4.36Å; P158-W280 HydrophobicContact CB-CZ3 4.15Å; P158-W280 WeakPolarHBondContact O-CH2 3.5Å; P158-W280 WeakPolarHBondContact O-CZ3 3.26Å; A160-W280 HydrophobicContact CB-CH2 3.82Å; A160-W280 HydrophobicContact CB-CZ2 4.3Å; A160-W280 HydrophobicContact CB-CZ3 4.37Å; Y276-W280 HydrophobicContact CD2-CB 4.47Å; Y276-W280 AromaticContact CD2-CD2 3.94Å; Y276-W280 HydrophobicContact CD2-CD2 3.94Å; Y276-W280 AromaticContact CD2-CE3 3.15Å; Y276-W280 HydrophobicContact CD2-CE3 3.15Å; Y276-W280 AromaticContact CD2-CZ3 3.56Å; Y276-W280 HydrophobicContact CD2-CZ3 3.56Å; Y276-W280 HydrophobicContact CE2-CB 4.04Å; Y276-W280 AromaticContact CE2-CD2 3.92Å; Y276-W280 HydrophobicContact CE2-CD2 3.92Å; Y276-W280 AromaticContact CE2-CE3 3.62Å; Y276-W280 HydrophobicContact CE2-CE3 3.62Å; Y276-W280 HydrophobicContact CE2-CG 4.13Å; Y276-W280 HydrophobicContact CE2-CZ3 4.28Å; Y276-W280 AromaticContact CG-CE3 3.87Å; Y276-W280 HydrophobicContact CG-CE3 3.87Å; Y276-W280 HydrophobicContact CG-CZ3 4.34Å; Y276-W280 PolarHBondContact O-N 2.96Å
281A95.8Very high97.4Very high20 Ų208.4 Ų8.417%0.1654%0.043CC..SBendtrans-97-2.2-177.500000114L186 Y276 N277 C283L186-A281 HydrophobicContact CB-CB 4.04Å; L186-A281 HydrophobicContact CD1-CB 4.2Å; L186-A281 HydrophobicContact CD2-CB 3.9Å; L186-A281 HydrophobicContact CG-CB 4.28Å; Y276-A281 PolarHBondContact O-N 3.39Å; N277-A281 CarbonylContact O-C 3.58Å; N277-A281 VanDerWaalsContact O-C 3.29Å; N277-A281 WeakPolarHBondContact O-CA 3.4Å; N277-A281 WeakPolarHBondContact O-CB 3.5Å; N277-A281 PolarHBondContact O-N 3.31Å; N277-A281 VanDerWaalsContact O-N 3.1Å; A281-C283 HydrophobicContact CB-CB 4.44Å; A281-C283 PolarHBondContact O-N 3.47Å; A281-C283 VanDerWaalsContact O-N 3.14Å
282Q96.3Very high97.4Very high51 Ų5110 Ų1024%0.2385%0.054CC..  trans57.224.2-177.7-46.3-179.5157.600113.4N277 F351 R352N277-Q282 PolarHBondContact O-N 3.18Å; Q282-F351 HydrophobicContact CB-CD1 3.88Å; Q282-F351 HydrophobicContact CB-CD2 4.41Å; Q282-F351 HydrophobicContact CB-CE1 3.74Å; Q282-F351 HydrophobicContact CB-CE2 4.26Å; Q282-F351 HydrophobicContact CB-CG 4.23Å; Q282-F351 HydrophobicContact CB-CZ 3.93Å; Q282-F351 HydrophobicContact CG-CD1 4.5Å; Q282-F351 HydrophobicContact CG-CD2 4.45Å; Q282-F351 HydrophobicContact CG-CG 4.38Å; Q282-F351 WeakPolarHBondContact O-CE1 3.33Å; Q282-R352 PolarHBondContact NE2-O 3.09Å
283C98.4Very high97.4Very high0 Ų011.1 Ų11.10%06%0.061CC..  trans-110.9126.3-177.4177.10000108.9F191 S194 N277 Y278 A281 E285F191-C283 HydrophobicContact CB-CB 3.97Å; F191-C283 WeakPolarHBondContact O-CB 3.37Å; S194-C283 VanDerWaalsContact CB-SG 3.52Å; N277-C283 CarbonylContact C-O 3.08Å; N277-C283 HydrophobicContact CB-CB 4.26Å; N277-C283 WeakPolarHBondContact CB-O 3.21Å; N277-C283 PolarHBondContact O-N 3.45Å; Y278-C283 VanDerWaalsContact CA-O 3.26Å; Y278-C283 WeakPolarHBondContact CA-O 3.45Å; Y278-C283 PolarHBondContact N-O 2.84Å; A281-C283 HydrophobicContact CB-CB 4.44Å; A281-C283 PolarHBondContact O-N 3.47Å; A281-C283 VanDerWaalsContact O-N 3.14Å; C283-E285 PolarHBondContact O-N 3.03Å
284L98.8Very high97.3Very high3 Ų312.9 Ų12.92%0.0167%0.069CC..EExtended strand (participates in β ladder)trans-78.6117.3174.9-78.871.5000108.2V192 L193 S194 D226 V229 F230 L233 Y278 F351 L362V192-L284 PolarHBondContact O-N 2.92Å; V192-L284 VanDerWaalsContact O-N 3.11Å; L193-L284 CarbonylContact C-O 3.5Å; L193-L284 WeakPolarHBondContact CA-O 3.49Å; L193-L284 HydrophobicContact CD1-CB 4.28Å; S194-L284 PolarHBondContact N-O 3.36Å; D226-L284 HydrophobicContact CB-CD2 4.4Å; V229-L284 HydrophobicContact CB-CD2 4.4Å; V229-L284 HydrophobicContact CG1-CD2 3.79Å; F230-L284 HydrophobicContact CD1-CD2 4.45Å; F230-L284 HydrophobicContact CE1-CB 3.73Å; F230-L284 HydrophobicContact CE1-CD2 4.08Å; F230-L284 HydrophobicContact CE1-CG 3.86Å; F230-L284 HydrophobicContact CE2-CD2 4.32Å; F230-L284 HydrophobicContact CE2-CG 4.3Å; F230-L284 HydrophobicContact CZ-CB 3.97Å; F230-L284 HydrophobicContact CZ-CD2 4.01Å; F230-L284 HydrophobicContact CZ-CG 3.63Å; L233-L284 HydrophobicContact CD1-CB 4.41Å; L233-L284 HydrophobicContact CD1-CD2 4.14Å; Y278-L284 HydrophobicContact CD2-CD1 4.16Å; Y278-L284 HydrophobicContact CD2-CG 4.12Å; Y278-L284 HydrophobicContact CE2-CD1 4.27Å; Y278-L284 HydrophobicContact CE2-CG 4.3Å; L284-F351 HydrophobicContact CD1-CZ 4.18Å; L284-L362 HydrophobicContact CB-CD1 4.18Å; L284-L362 HydrophobicContact CD1-CD1 4.3Å; L284-L362 HydrophobicContact CD2-CB 4.32Å; L284-L362 HydrophobicContact CD2-CD1 4.11Å; L284-L362 HydrophobicContact CG-CD1 4.42Å
285E98.9Very high97.2Very high0 Ų013.6 Ų13.60%07%0.072CC..EExtended strand (participates in β ladder)trans-117.1138.6178.3-172.8165.5100.400111.1K78 S194 N196 P207 Q274 N277 C283K78-E285 IonicContact NZ-OE2 3.97Å; K78-E285 PolarHBondContact NZ-OE2 3.41Å; S194-E285 VanDerWaalsContact CB-OE2 3.3Å; S194-E285 WeakPolarHBondContact CB-OE2 3.47Å; S194-E285 WeakPolarHBondContact O-CA 3.45Å; S194-E285 PolarHBondContact OG-OE2 2.92Å; N196-E285 PolarHBondContact ND2-OE1 3.41Å; P207-E285 WeakPolarHBondContact CD-O 2.97Å; Q274-E285 HydrophobicContact CG-CB 4.37Å; Q274-E285 HydrophobicContact CG-CG 4.48Å; Q274-E285 WeakPolarHBondContact CG-O 3.48Å; N277-E285 HydrophobicContact CB-CB 3.72Å; N277-E285 VanDerWaalsContact ND2-CD 3.26Å; N277-E285 PolarHBondContact ND2-OE1 3.26Å; N277-E285 PolarHBondContact ND2-OE2 3.11Å; N277-E285 VanDerWaalsContact ND2-OE2 3.1Å; N277-E285 PolarHBondContact OD1-OE2 3.36Å; C283-E285 PolarHBondContact O-N 3.03Å
286L98.9Very high97.1Very high0 Ų013.5 Ų13.50%07%0.072CC..EExtended strand (participates in β ladder)trans-107.3154.8166-64.9-170.6000111.2S194 A195 N196 F230 L233 A234 L288 Y315S194-L286 PolarHBondContact O-N 3.43Å; A195-L286 CarbonylContact C-O 3.6Å; A195-L286 WeakPolarHBondContact CA-O 3.33Å; A195-L286 HydrophobicContact CB-CB 4.39Å; N196-L286 PolarHBondContact N-O 3.09Å; N196-L286 PolarHBondContact ND2-O 3.25Å; F230-L286 HydrophobicContact CD1-CD2 3.77Å; F230-L286 HydrophobicContact CE1-CD2 4.41Å; L233-L286 HydrophobicContact CB-CD1 3.98Å; A234-L286 HydrophobicContact CB-CD1 3.96Å; L286-L288 HydrophobicContact CB-CD2 4.22Å; L286-L288 HydrophobicContact CD1-CD2 4.41Å; L286-Y315 HydrophobicContact CD1-CE2 3.54Å; L286-Y315 HydrophobicContact CG-CE2 4.14Å; L286-Y315 VanDerWaalsContact CG-OH 3.31Å; L286-Y315 WeakPolarHBondContact CG-OH 3.18Å
287T98.9Very high97.1Very high8 Ų818.5 Ų18.55%0.04910%0.095CC..EExtended strand (participates in β ladder)trans-101.7118167-58.10000108.4N196 H198 S205 Q274N196-T287 PolarHBondContact ND2-OG1 2.97Å; N196-T287 WeakPolarHBondContact O-CA 3.43Å; N196-T287 WeakPolarHBondContact OD1-CG2 3.36Å; N196-T287 PolarHBondContact OD1-OG1 3.23Å; H198-T287 HydrophobicContact CB-CG2 4.45Å; S205-T287 PolarHBondContact N-O 3.27Å; S205-T287 PolarHBondContact O-N 3.34Å; Q274-T287 VanDerWaalsContact OE1-CB 3.25Å; Q274-T287 PolarHBondContact OE1-OG1 3.41Å
288L98.9Very high97Very high0 Ų021.1 Ų21.10%011%0.112CC..EExtended strand (participates in β ladder)trans-106107.7-176.9-57.8176.8000109.6Y79 A195 N196 L197 H198 A204 Y237 L286 L290Y79-L288 HydrophobicContact CE1-CD1 4.18Å; A195-L288 HydrophobicContact CB-CD1 3.54Å; A195-L288 HydrophobicContact CB-CG 3.87Å; N196-L288 PolarHBondContact O-N 3.18Å; L197-L288 HydrophobicContact CD1-CD1 4.27Å; H198-L288 PolarHBondContact N-O 2.89Å; A204-L288 HydrophobicContact CB-CD2 3.81Å; Y237-L288 HydrophobicContact CD1-CD1 4.39Å; Y237-L288 HydrophobicContact CD1-CD2 3.93Å; Y237-L288 HydrophobicContact CD2-CD1 3.59Å; Y237-L288 HydrophobicContact CD2-CD2 4.15Å; Y237-L288 HydrophobicContact CE1-CD1 4.25Å; Y237-L288 HydrophobicContact CE1-CD2 4.39Å; Y237-L288 HydrophobicContact CE2-CD1 3.43Å; Y237-L288 VanDerWaalsContact CE2-CD1 3.43Å; Y237-L288 HydrophobicContact CG-CD1 4.08Å; Y237-L288 HydrophobicContact CG-CD2 3.8Å; L286-L288 HydrophobicContact CB-CD2 4.22Å; L286-L288 HydrophobicContact CD1-CD2 4.41Å; L288-L290 HydrophobicContact CB-CD2 3.8Å; L288-L290 WeakPolarHBondContact O-CG 3.25Å
289E98.4Very high97Very high13 Ų1329.4 Ų29.46%0.06115%0.148CC..EExtended strand (participates in β ladder)trans-86.8110.6173.4-66.4-73.9178.700108.8H198 G199 A201 M202 V203 M244 W266H198-E289 VanDerWaalsContact CB-CD 3.42Å; H198-E289 HydrophobicContact CB-CG 4.37Å; H198-E289 WeakPolarHBondContact CB-OE1 3.37Å; H198-E289 VanDerWaalsContact CB-OE2 3.31Å; H198-E289 WeakPolarHBondContact CB-OE2 3.18Å; G199-E289 WeakPolarHBondContact CA-OE2 2.91Å; G199-E289 PolarHBondContact N-OE2 2.84Å; A201-E289 HydrophobicContact CB-CB 3.89Å; A201-E289 HydrophobicContact CB-CG 4.05Å; A201-E289 CarbonylContact O-C 3.2Å; A201-E289 WeakPolarHBondContact O-CB 3.42Å; M202-E289 WeakPolarHBondContact CA-O 3.22Å; V203-E289 HydrophobicContact CG1-CB 3.99Å; V203-E289 HydrophobicContact CG1-CG 4.06Å; V203-E289 PolarHBondContact N-O 3.04Å; V203-E289 VanDerWaalsContact N-O 3.14Å; V203-E289 WeakPolarHBondContact O-CB 2.82Å; V203-E289 PolarHBondContact O-N 2.91Å; M244-E289 VanDerWaalsContact CE-O 3.24Å; M244-E289 WeakPolarHBondContact CE-O 3.47Å; W266-E289 HydrophobicContact CH2-CG 3.89Å; W266-E289 HydrophobicContact CZ3-CG 3.98Å
290L98.1Very high97.1Very high0 Ų033 Ų330%017%0.165CC..EExtended strand (participates in β ladder)trans-98.7-20.5-162-57.3178.2000114.3L89 L93 L197 H198 Y237 L288L89-L290 HydrophobicContact CD2-CB 3.8Å; L89-L290 HydrophobicContact CG-CB 4.42Å; L93-L290 HydrophobicContact CD1-CD1 3.68Å; L197-L290 HydrophobicContact CB-CD1 3.85Å; L197-L290 HydrophobicContact CD2-CD1 3.81Å; L197-L290 HydrophobicContact CG-CD1 3.82Å; H198-L290 PolarHBondContact O-N 3.03Å; Y237-L290 HydrophobicContact CE1-CD2 3.97Å; Y237-L290 VanDerWaalsContact OH-CD2 3.3Å; Y237-L290 WeakPolarHBondContact OH-CD2 3.16Å; L288-L290 HydrophobicContact CB-CD2 3.8Å; L288-L290 WeakPolarHBondContact O-CG 3.25Å
291S95.7Very high97.3Very high5 Ų530.6 Ų30.64%0.03516%0.156CC..EExtended strand (participates in β ladder)trans-157.4137.9-175.352.80000110.9L89 G200 A201 C293L89-S291 WeakPolarHBondContact CD2-OG 3.43Å; G200-S291 PolarHBondContact N-O 3.41Å; A201-S291 PolarHBondContact N-O 2.82Å; A201-S291 CarbonylContact O-C 3.57Å; A201-S291 PolarHBondContact O-N 2.99Å; A201-S291 VanDerWaalsContact O-N 3.15Å; A201-S291 VanDerWaalsContact O-O 3.09Å; S291-C293 WeakPolarHBondContact CB-O 3.32Å; S291-C293 PolarHBondContact O-N 2.96Å; S291-C293 PolarHBondContact OG-O 2.71Å
292C94.5Very high97.4Very high36 Ų3632.1 Ų32.124%0.24316%0.164CC..SBendtrans-57.1-40.1171.3-48.20000111G200 C250G200-C292 WeakPolarHBondContact CA-O 3.36Å; C250-C292 WeakPolarHBondContact CA-SG 3.26Å; C250-C292 HydrophobicContact CB-CB 3.66Å; C250-C292 WeakPolarHBondContact CB-SG 3.37Å; C250-C292 WeakPolarHBondContact SG-CA 3.27Å; C250-C292 WeakPolarHBondContact SG-CB 3.29Å; C250-C292 CovalentContact SG-SG 2.03Å; C250-C292 PolarHBondContact SG-SG 3.35Å
293C95.6Very high97.5Very high27 Ų2732.4 Ų32.418%0.18218%0.175CC..SBendtrans-80.6121.4174.8-151.90000110.8C139 S291 F295 P296C139-C293 WeakPolarHBondContact CA-SG 3.42Å; C139-C293 HydrophobicContact CB-CB 4.34Å; C139-C293 WeakPolarHBondContact CB-SG 3.36Å; C139-C293 WeakPolarHBondContact SG-CA 3.48Å; C139-C293 WeakPolarHBondContact SG-CB 3.44Å; C139-C293 CovalentContact SG-SG 2.04Å; C139-C293 PolarHBondContact SG-SG 2.97Å; S291-C293 WeakPolarHBondContact CB-O 3.32Å; S291-C293 PolarHBondContact O-N 2.96Å; S291-C293 PolarHBondContact OG-O 2.71Å; C293-F295 VanDerWaalsContact C-N 3.33Å; C293-P296 HydrophobicContact CB-CB 4.32Å
294K96.3Very high97.5Very high36 Ų3633.7 Ų33.716%0.15718%0.182CC..SBendtrans-66.3-39177.2-63.8-177.6176.3169.20111.9N86 E87 V88 C139N86-K294 CarbonylContact O-C 3.54Å; N86-K294 WeakPolarHBondContact O-CB 3.27Å; N86-K294 VanDerWaalsContact O-O 3.1Å; E87-K294 HydrophobicContact CG-CB 4.2Å; E87-K294 HydrophobicContact CG-CD 4.15Å; E87-K294 HydrophobicContact CG-CG 4.07Å; V88-K294 PolarHBondContact N-O 3.49Å; V88-K294 VanDerWaalsContact N-O 3.09Å; C139-K294 WeakPolarHBondContact O-CB 3.43Å; C139-K294 PolarHBondContact O-N 3.17Å
295F97.1Very high97.5Very high15 Ų1534.2 Ų34.27%0.06618%0.183CC..SBendtrans-126.476.2-179.7-143.6-58.4000111.3Y22 V88 F132 A135 D136 T137 N138 C293Y22-F295 HydrophobicContact CD1-CE1 4.24Å; Y22-F295 HydrophobicContact CD2-CD1 4.46Å; Y22-F295 AromaticContact CD2-CE1 3.55Å; Y22-F295 HydrophobicContact CD2-CE1 3.55Å; Y22-F295 HydrophobicContact CD2-CZ 4.27Å; Y22-F295 HydrophobicContact CE1-CD1 4.44Å; Y22-F295 HydrophobicContact CE1-CE1 4.04Å; Y22-F295 AromaticContact CE2-CD1 3.76Å; Y22-F295 HydrophobicContact CE2-CD1 3.76Å; Y22-F295 AromaticContact CE2-CE1 3.28Å; Y22-F295 HydrophobicContact CE2-CE1 3.28Å; Y22-F295 HydrophobicContact CE2-CZ 4.34Å; Y22-F295 HydrophobicContact CG-CE1 4.02Å; Y22-F295 HydrophobicContact CG-CZ 4.37Å; Y22-F295 AromaticContact CZ-CD1 3.74Å; Y22-F295 AromaticContact CZ-CE1 3.53Å; V88-F295 HydrophobicContact CB-CD2 4.34Å; V88-F295 HydrophobicContact CB-CE2 4.31Å; V88-F295 HydrophobicContact CG1-CD2 3.56Å; V88-F295 HydrophobicContact CG1-CE2 3.38Å; V88-F295 HydrophobicContact CG1-CG 4.26Å; V88-F295 HydrophobicContact CG1-CZ 3.94Å; V88-F295 HydrophobicContact CG2-CB 4.18Å; V88-F295 HydrophobicContact CG2-CD1 3.69Å; V88-F295 HydrophobicContact CG2-CD2 3.79Å; V88-F295 HydrophobicContact CG2-CE1 3.97Å; V88-F295 HydrophobicContact CG2-CE2 4.07Å; V88-F295 HydrophobicContact CG2-CG 3.59Å; V88-F295 HydrophobicContact CG2-CZ 4.14Å; F132-F295 HydrophobicContact CE2-CZ 4.46Å; A135-F295 HydrophobicContact CB-CE2 4.15Å; D136-F295 WeakPolarHBondContact O-CD2 3.3Å; D136-F295 WeakPolarHBondContact O-CE2 3.16Å; T137-F295 HydrophobicContact CG2-CD1 4.4Å; T137-F295 HydrophobicContact CG2-CE1 3.92Å; T137-F295 HydrophobicContact CG2-CE2 4.43Å; T137-F295 HydrophobicContact CG2-CZ 3.96Å; N138-F295 VanDerWaalsContact O-CB 3.26Å; N138-F295 WeakPolarHBondContact O-CB 3.46Å; C293-F295 VanDerWaalsContact C-N 3.33Å
296P96.9Very high97.5Very high4 Ų440.3 Ų40.33%0.02621%0.214CC..  trans-64.1165.6-178.825.7-32000112.5Y22 C293 L301 L304Y22-P296 WeakPolarHBondContact OH-CD 3.45Å; Y22-P296 PolarHBondContact OH-O 2.96Å; C293-P296 HydrophobicContact CB-CB 4.32Å; P296-L301 HydrophobicContact CG-CD2 4.41Å; P296-L304 HydrophobicContact CB-CD1 3.94Å; P296-L304 HydrophobicContact CG-CD1 3.83Å
297Q96.2Very high97.5Very high109 Ų10942.9 Ų42.951%0.50923%0.227SC..  trans-73144176.9-66.7-71.6-31.800110.5K299 E300Q297-K299 HydrophobicContact CB-CG 4.05Å; Q297-K299 PolarHBondContact O-N 2.88Å; Q297-E300 HydrophobicContact CB-CG 4.35Å; Q297-E300 WeakPolarHBondContact CB-OE2 3.19Å; Q297-E300 PolarHBondContact N-OE2 2.74Å; Q297-E300 WeakPolarHBondContact O-CB 3.45Å; Q297-E300 PolarHBondContact O-N 3.11Å
298P96.3Very high97.5Very high56 Ų5642.5 Ų42.536%0.36423%0.225SC..G310 helixtrans-52.9-33.4-178.5-29.334.9000114.9Y22 E300 L301Y22-P298 HydrophobicContact CD2-CG 3.96Å; Y22-P298 HydrophobicContact CE2-CG 3.8Å; P298-E300 PolarHBondContact O-N 3.17Å; P298-E300 VanDerWaalsContact O-N 3.16Å; P298-L301 HydrophobicContact CB-CD1 4.37Å; P298-L301 WeakPolarHBondContact O-CB 3.31Å; P298-L301 WeakPolarHBondContact O-CG 3.39Å; P298-L301 PolarHBondContact O-N 2.91Å
299K97.4Very high97.5Very high176 Ų17644.9 Ų44.977%0.76524%0.235SC*.G310 helixtrans-61.6-19.9177.267.6-179.9-179.8177.20114.2Q297Q297-K299 HydrophobicContact CB-CG 4.05Å; Q297-K299 PolarHBondContact O-N 2.88Å
300E97.9Very high97.5Very high84 Ų8450.7 Ų50.739%0.39326%0.26SS..G310 helixtrans-88.8-20.8-178.8-57.3176.894.600112Q297 P298 P302 A303 L304Q297-E300 HydrophobicContact CB-CG 4.35Å; Q297-E300 WeakPolarHBondContact CB-OE2 3.19Å; Q297-E300 PolarHBondContact N-OE2 2.74Å; Q297-E300 WeakPolarHBondContact O-CB 3.45Å; Q297-E300 PolarHBondContact O-N 3.11Å; P298-E300 PolarHBondContact O-N 3.17Å; P298-E300 VanDerWaalsContact O-N 3.16Å; E300-P302 VanDerWaalsContact C-CD 3.47Å; E300-A303 PolarHBondContact O-N 3.4Å; E300-A303 VanDerWaalsContact O-N 3.09Å; E300-L304 HydrophobicContact CB-CD1 4Å; E300-L304 HydrophobicContact CB-CG 4.5Å; E300-L304 WeakPolarHBondContact O-CG 3.49Å; E300-L304 PolarHBondContact O-N 3.19Å
301L98.3Very high97.5Very high0 Ų050.7 Ų50.70%026%0.26CS..Hα-helixtrans-55.6-41.1-174.5-61.3174.6000114.3F20 Y22 L89 V92 P296 P298 A303 L304 W305F20-L301 HydrophobicContact CB-CB 4.17Å; F20-L301 HydrophobicContact CD1-CB 4.02Å; Y22-L301 HydrophobicContact CE1-CD1 4.21Å; Y22-L301 HydrophobicContact CE1-CD2 4.15Å; L89-L301 HydrophobicContact CD1-CD2 4.05Å; V92-L301 HydrophobicContact CG1-CD1 4.34Å; V92-L301 HydrophobicContact CG1-CD2 4.38Å; V92-L301 HydrophobicContact CG2-CD1 4.39Å; V92-L301 HydrophobicContact CG2-CD2 4.34Å; P296-L301 HydrophobicContact CG-CD2 4.41Å; P298-L301 HydrophobicContact CB-CD1 4.37Å; P298-L301 WeakPolarHBondContact O-CB 3.31Å; P298-L301 WeakPolarHBondContact O-CG 3.39Å; P298-L301 PolarHBondContact O-N 2.91Å; L301-A303 VanDerWaalsContact C-N 3.34Å; L301-A303 PolarHBondContact O-N 3.09Å; L301-L304 PolarHBondContact O-N 2.72Å; L301-W305 WeakPolarHBondContact O-CB 3.36Å; L301-W305 PolarHBondContact O-N 3.02Å
302P98.1Very high97.7Very high51 Ų5150.4 Ų50.433%0.33126%0.259SS..Hα-helixtrans-62-40.5176.9-21.432000113.1F20 E300 M306F20-P302 HydrophobicContact CB-CG 3.73Å; F20-P302 HydrophobicContact CD1-CB 4.48Å; F20-P302 HydrophobicContact CD1-CG 4.29Å; F20-P302 HydrophobicContact CD2-CB 4.08Å; F20-P302 HydrophobicContact CD2-CG 3.89Å; F20-P302 HydrophobicContact CE2-CB 4.33Å; F20-P302 HydrophobicContact CG-CB 4.16Å; F20-P302 HydrophobicContact CG-CG 3.71Å; E300-P302 VanDerWaalsContact C-CD 3.47Å; P302-M306 WeakPolarHBondContact O-CG 3.28Å; P302-M306 PolarHBondContact O-N 3Å; P302-M306 VanDerWaalsContact O-N 3.1Å
303A98.4Very high97.9Very high58 Ų5849.9 Ų49.948%0.47925%0.253SS..Hα-helixtrans-69.4-45.3178.800000110.8E300 L301 W305 M306 D307E300-A303 PolarHBondContact O-N 3.4Å; E300-A303 VanDerWaalsContact O-N 3.09Å; L301-A303 VanDerWaalsContact C-N 3.34Å; L301-A303 PolarHBondContact O-N 3.09Å; A303-W305 VanDerWaalsContact C-N 3.26Å; A303-W305 PolarHBondContact O-N 3.39Å; A303-M306 WeakPolarHBondContact O-CB 3.41Å; A303-M306 PolarHBondContact O-N 2.9Å; A303-D307 PolarHBondContact O-N 3.33Å
304L98.4Very high98Very high27 Ų2749.1 Ų49.114%0.14125%0.249CC..Hα-helixtrans-61.2-34.8176.9-67.2167.6000112.4L89 P296 E300 L301 D307 N308L89-L304 HydrophobicContact CD1-CB 3.84Å; L89-L304 HydrophobicContact CD1-CD1 3.9Å; L89-L304 HydrophobicContact CD1-CG 4.48Å; L89-L304 HydrophobicContact CD2-CB 4.18Å; L89-L304 HydrophobicContact CD2-CD1 4.08Å; L89-L304 HydrophobicContact CD2-CD2 4.25Å; L89-L304 HydrophobicContact CD2-CG 4.4Å; P296-L304 HydrophobicContact CB-CD1 3.94Å; P296-L304 HydrophobicContact CG-CD1 3.83Å; E300-L304 HydrophobicContact CB-CD1 4Å; E300-L304 HydrophobicContact CB-CG 4.5Å; E300-L304 WeakPolarHBondContact O-CG 3.49Å; E300-L304 PolarHBondContact O-N 3.19Å; L301-L304 PolarHBondContact O-N 2.72Å; L304-D307 PolarHBondContact O-N 2.71Å; L304-N308 PolarHBondContact O-N 3.03Å; L304-N308 PolarHBondContact O-ND2 3.34Å
305W98.7Very high98.2Very high13 Ų1347.4 Ų47.45%0.04924%0.242CC..Hα-helixtrans-64.3-47170.4165.6-109.6000112.4F20 L93 Q96 L97 E100 L301 A303 D307 N308 K309 L312F20-W305 HydrophobicContact CE1-CB 3.52Å; F20-W305 AromaticContact CE1-CD1 3.97Å; F20-W305 AromaticContact CE1-CG 3.78Å; F20-W305 HydrophobicContact CE1-CG 3.78Å; F20-W305 HydrophobicContact CZ-CB 3.98Å; F20-W305 AromaticContact CZ-CD1 3.52Å; F20-W305 AromaticContact CZ-CG 3.82Å; F20-W305 HydrophobicContact CZ-CG 3.82Å; L93-W305 HydrophobicContact CD2-CB 4.07Å; L93-W305 HydrophobicContact CD2-CE3 3.96Å; L93-W305 WeakPolarHBondContact O-CZ3 3.39Å; Q96-W305 HydrophobicContact CB-CD2 3.78Å; Q96-W305 HydrophobicContact CB-CE3 3.58Å; Q96-W305 HydrophobicContact CB-CG 4.47Å; Q96-W305 HydrophobicContact CB-CH2 4.12Å; Q96-W305 HydrophobicContact CB-CZ2 4.25Å; Q96-W305 HydrophobicContact CB-CZ3 3.77Å; L97-W305 HydrophobicContact CB-CH2 4.16Å; L97-W305 HydrophobicContact CB-CZ3 4.17Å; L97-W305 HydrophobicContact CD1-CH2 4.49Å; E100-W305 HydrophobicContact CB-CH2 4.24Å; E100-W305 HydrophobicContact CB-CZ2 3.99Å; E100-W305 HydrophobicContact CG-CZ2 4.28Å; L301-W305 WeakPolarHBondContact O-CB 3.36Å; L301-W305 PolarHBondContact O-N 3.02Å; A303-W305 VanDerWaalsContact C-N 3.26Å; A303-W305 PolarHBondContact O-N 3.39Å; W305-D307 PolarHBondContact O-N 3.26Å; W305-N308 PolarHBondContact O-N 3.23Å; W305-N308 VanDerWaalsContact O-N 3.13Å; W305-K309 HydrophobicContact CD2-CB 4.21Å; W305-K309 HydrophobicContact CE3-CB 4.45Å; W305-K309 HydrophobicContact CH2-CB 4.08Å; W305-K309 HydrophobicContact CH2-CD 4.47Å; W305-K309 HydrophobicContact CH2-CG 3.96Å; W305-K309 HydrophobicContact CZ2-CB 3.85Å; W305-K309 HydrophobicContact CZ2-CD 3.62Å; W305-K309 HydrophobicContact CZ2-CG 3.59Å; W305-K309 HydrophobicContact CZ3-CB 4.38Å; W305-K309 WeakPolarHBondContact O-CB 3.44Å; W305-K309 PolarHBondContact O-N 3.39Å; W305-L312 HydrophobicContact CZ3-CD1 3.89Å
306M98.6Very high98.3Very high129 Ų12946.7 Ų46.764%0.63524%0.238SC*.Hα-helixtrans-59.9-36.5177.4-72.8-60.2-58.900112.1P302 A303 N308P302-M306 WeakPolarHBondContact O-CG 3.28Å; P302-M306 PolarHBondContact O-N 3Å; P302-M306 VanDerWaalsContact O-N 3.1Å; A303-M306 WeakPolarHBondContact O-CB 3.41Å; A303-M306 PolarHBondContact O-N 2.9Å; M306-N308 VanDerWaalsContact C-N 3.3Å; M306-N308 PolarHBondContact O-N 3.31Å
307D98.6Very high98.3Very high54 Ų5449 Ų4929%0.28925%0.249SC..Hα-helixtrans-66.8-30.8177.8-68.8-17.1000113H241 A242 A303 L304 W305H241-D307 WeakPolarHBondContact CA-O 3.23Å; H241-D307 PolarHBondContact CD2-O 2.94Å; A242-D307 HydrophobicContact CB-CB 3.75Å; A242-D307 WeakPolarHBondContact CB-OD1 3.46Å; A242-D307 PolarHBondContact N-O 3.31Å; A242-D307 VanDerWaalsContact N-O 3.16Å; A303-D307 PolarHBondContact O-N 3.33Å; L304-D307 PolarHBondContact O-N 2.71Å; W305-D307 PolarHBondContact O-N 3.26Å
308N98.9Very high98.5Very high0 Ų044 Ų440%023%0.226CC..Hα-helixtrans-103.4-26.1-173.1-78-85.6000114.7L93 Y237 H241 L304 W305 M306 K310 A311 L312L93-N308 HydrophobicContact CD1-CB 3.65Å; Y237-N308 PolarHBondContact OH-OD1 3.26Å; H241-N308 VanDerWaalsContact CD2-CG 3.44Å; H241-N308 PolarHBondContact CD2-OD1 3.45Å; H241-N308 PolarHBondContact NE2-ND2 2.78Å; H241-N308 VanDerWaalsContact NE2-ND2 3.15Å; H241-N308 PolarHBondContact NE2-OD1 3.07Å; L304-N308 PolarHBondContact O-N 3.03Å; L304-N308 PolarHBondContact O-ND2 3.34Å; W305-N308 PolarHBondContact O-N 3.23Å; W305-N308 VanDerWaalsContact O-N 3.13Å; M306-N308 VanDerWaalsContact C-N 3.3Å; M306-N308 PolarHBondContact O-N 3.31Å; N308-K310 VanDerWaalsContact C-N 3.3Å; N308-K310 PolarHBondContact O-N 3.09Å; N308-A311 WeakPolarHBondContact O-CA 3.44Å; N308-A311 WeakPolarHBondContact O-CB 3.5Å; N308-A311 PolarHBondContact O-N 2.85Å; N308-L312 HydrophobicContact CB-CD1 4.25Å; N308-L312 PolarHBondContact O-N 2.86Å
309K98.8Very high98.6Very high49 Ų4941.5 Ų41.521%0.21321%0.209CC..Hα-helixtrans-50.1-48.4-172.2173.7179174.41680112.7E100 W305 L313E100-K309 VanDerWaalsContact CD-CE 3.42Å; E100-K309 VanDerWaalsContact OE1-CE 3.23Å; E100-K309 WeakPolarHBondContact OE1-CE 3.46Å; E100-K309 IonicContact OE1-NZ 3.65Å; E100-K309 PolarHBondContact OE1-NZ 2.76Å; E100-K309 IonicContact OE2-NZ 3.87Å; E100-K309 PolarHBondContact OE2-NZ 3.11Å; W305-K309 HydrophobicContact CD2-CB 4.21Å; W305-K309 HydrophobicContact CE3-CB 4.45Å; W305-K309 HydrophobicContact CH2-CB 4.08Å; W305-K309 HydrophobicContact CH2-CD 4.47Å; W305-K309 HydrophobicContact CH2-CG 3.96Å; W305-K309 HydrophobicContact CZ2-CB 3.85Å; W305-K309 HydrophobicContact CZ2-CD 3.62Å; W305-K309 HydrophobicContact CZ2-CG 3.59Å; W305-K309 HydrophobicContact CZ3-CB 4.38Å; W305-K309 WeakPolarHBondContact O-CB 3.44Å; W305-K309 PolarHBondContact O-N 3.39Å; K309-L313 HydrophobicContact CG-CD1 4.34Å; K309-L313 WeakPolarHBondContact O-CG 3.4Å; K309-L313 PolarHBondContact O-N 3.29Å
310K98.8Very high98.7Very high135 Ų13533.1 Ų33.159%0.58717%0.173SC*.Hα-helixtrans-65.5-41.3179.9-169.8-171.4-179.7-1570111.6N240 N308 A314N240-K310 HydrophobicContact CB-CD 4.41Å; N240-K310 HydrophobicContact CB-CG 4.32Å; N240-K310 WeakPolarHBondContact OD1-CE 3.48Å; N240-K310 PolarHBondContact OD1-NZ 2.79Å; N240-K310 VanDerWaalsContact OD1-NZ 3.12Å; N308-K310 VanDerWaalsContact C-N 3.3Å; N308-K310 PolarHBondContact O-N 3.09Å; K310-A314 WeakPolarHBondContact O-CB 3.16Å; K310-A314 PolarHBondContact O-N 3.43Å
311A98.9Very high98.7Very high0 Ų029.2 Ų29.20%016%0.155CC..Hα-helixtrans-64-45.5179.100000112.2Y237 N240 H241 N308 L313 A314 Y315Y237-A311 HydrophobicContact CD1-CB 4.07Å; Y237-A311 HydrophobicContact CD2-CB 3.82Å; Y237-A311 HydrophobicContact CE1-CB 3.94Å; Y237-A311 HydrophobicContact CE2-CB 3.68Å; Y237-A311 HydrophobicContact CG-CB 4.01Å; Y237-A311 WeakPolarHBondContact O-CB 3.47Å; N240-A311 HydrophobicContact CB-CB 4.07Å; H241-A311 HydrophobicContact CB-CB 4.27Å; N308-A311 WeakPolarHBondContact O-CA 3.44Å; N308-A311 WeakPolarHBondContact O-CB 3.5Å; N308-A311 PolarHBondContact O-N 2.85Å; A311-L313 PolarHBondContact O-N 3.27Å; A311-A314 PolarHBondContact O-N 2.87Å; A311-Y315 VanDerWaalsContact O-CB 3.28Å; A311-Y315 WeakPolarHBondContact O-CB 3.24Å; A311-Y315 PolarHBondContact O-N 3.25Å
312L98.9Very high98.7Very high0 Ų029.2 Ų29.20%016%0.155CC..Hα-helixtrans-58.1-50177-69.6165.6000111.3Y79 L93 L97 L197 Y237 W305 N308 Y315 I316Y79-L312 HydrophobicContact CE1-CD2 4.13Å; Y79-L312 HydrophobicContact CE2-CB 4.39Å; Y79-L312 HydrophobicContact CE2-CD2 3.79Å; Y79-L312 WeakPolarHBondContact OH-CA 3.25Å; Y79-L312 PolarHBondContact OH-O 3.32Å; L93-L312 HydrophobicContact CB-CD1 4.21Å; L93-L312 HydrophobicContact CD1-CD1 4.39Å; L97-L312 HydrophobicContact CD2-CB 4.49Å; L197-L312 HydrophobicContact CD2-CD2 4.29Å; Y237-L312 HydrophobicContact CE2-CD2 3.96Å; Y237-L312 HydrophobicContact CE2-CG 4.21Å; W305-L312 HydrophobicContact CZ3-CD1 3.89Å; N308-L312 HydrophobicContact CB-CD1 4.25Å; N308-L312 PolarHBondContact O-N 2.86Å; L312-Y315 PolarHBondContact O-N 2.84Å; L312-I316 WeakPolarHBondContact O-CG1 3.38Å; L312-I316 PolarHBondContact O-N 2.93Å; L312-I316 VanDerWaalsContact O-N 3.16Å
313L98.8Very high98.8Very high24 Ų2426.9 Ų26.913%0.12614%0.139CC..Hα-helixtrans-65.5-44179.5-68.2172000112.4L97 L101 W111 L115 K309 A311 Y315 I316 Q317L97-L313 HydrophobicContact CD1-CD2 3.83Å; L97-L313 HydrophobicContact CD1-CG 4.37Å; L101-L313 HydrophobicContact CD2-CD2 4.19Å; W111-L313 HydrophobicContact CE3-CD2 4.48Å; W111-L313 HydrophobicContact CH2-CD1 4.46Å; W111-L313 HydrophobicContact CZ3-CD1 4.14Å; W111-L313 HydrophobicContact CZ3-CD2 3.8Å; L115-L313 HydrophobicContact CD2-CD2 4.27Å; K309-L313 HydrophobicContact CG-CD1 4.34Å; K309-L313 WeakPolarHBondContact O-CG 3.4Å; K309-L313 PolarHBondContact O-N 3.29Å; A311-L313 PolarHBondContact O-N 3.27Å; L313-Y315 VanDerWaalsContact C-N 3.26Å; L313-Y315 PolarHBondContact O-N 3.32Å; L313-I316 PolarHBondContact O-N 3.2Å; L313-Q317 WeakPolarHBondContact O-CG 3.48Å; L313-Q317 PolarHBondContact O-N 2.79Å
314A98.8Very high98.8Very high12 Ų1224.5 Ų24.510%0.09912%0.118CC..Hα-helixtrans-63-33.6178.800000112.4V236 N240 K310 A311 Q318V236-A314 HydrophobicContact CG1-CB 4.13Å; N240-A314 HydrophobicContact CB-CB 4.26Å; K310-A314 WeakPolarHBondContact O-CB 3.16Å; K310-A314 PolarHBondContact O-N 3.43Å; A311-A314 PolarHBondContact O-N 2.87Å; A314-Q318 WeakPolarHBondContact O-CG 3.41Å; A314-Q318 PolarHBondContact O-NE2 3.39Å
315Y98.9Very high98.8Very high0 Ų023.7 Ų23.70%012%0.117CC..Hα-helixtrans-72.2-42.8177.7-173.6-97.1000112.4F77 Y79 L193 S194 A195 L233 Y237 L286 A311 L312 L313 Q317 Q318F77-Y315 AromaticContact CE2-CD1 3.75Å; F77-Y315 HydrophobicContact CE2-CD1 3.75Å; F77-Y315 AromaticContact CE2-CE1 3.81Å; F77-Y315 HydrophobicContact CE2-CE1 3.81Å; F77-Y315 AromaticContact CZ-CD1 3.87Å; F77-Y315 HydrophobicContact CZ-CD1 3.87Å; F77-Y315 HydrophobicContact CZ-CE1 4.08Å; Y79-Y315 HydrophobicContact CE1-CD1 4.02Å; Y79-Y315 HydrophobicContact CE1-CE1 4.35Å; Y79-Y315 AromaticContact CZ-CD1 3.83Å; Y79-Y315 WeakPolarHBondContact OH-CB 3.37Å; Y79-Y315 WeakPolarHBondContact OH-CD1 3.39Å; L193-Y315 HydrophobicContact CD1-CE1 4.28Å; L193-Y315 WeakPolarHBondContact CD1-OH 3.18Å; L193-Y315 HydrophobicContact CD2-CD1 4.46Å; L193-Y315 HydrophobicContact CD2-CE1 4.13Å; L193-Y315 WeakPolarHBondContact CD2-O 3.39Å; L193-Y315 HydrophobicContact CG-CE1 4.01Å; S194-Y315 WeakPolarHBondContact O-CE1 3.05Å; S194-Y315 PolarHBondContact O-OH 2.82Å; A195-Y315 HydrophobicContact CB-CD1 4.37Å; A195-Y315 HydrophobicContact CB-CE1 3.65Å; L233-Y315 HydrophobicContact CB-CE2 4.06Å; L233-Y315 HydrophobicContact CD2-CE2 4.28Å; Y237-Y315 HydrophobicContact CD2-CD2 4.5Å; Y237-Y315 HydrophobicContact CD2-CG 4.32Å; L286-Y315 HydrophobicContact CD1-CE2 3.54Å; L286-Y315 HydrophobicContact CG-CE2 4.14Å; L286-Y315 VanDerWaalsContact CG-OH 3.31Å; L286-Y315 WeakPolarHBondContact CG-OH 3.18Å; A311-Y315 VanDerWaalsContact O-CB 3.28Å; A311-Y315 WeakPolarHBondContact O-CB 3.24Å; A311-Y315 PolarHBondContact O-N 3.25Å; L312-Y315 PolarHBondContact O-N 2.84Å; L313-Y315 VanDerWaalsContact C-N 3.26Å; L313-Y315 PolarHBondContact O-N 3.32Å; Y315-Q317 PolarHBondContact O-N 3.04Å; Y315-Q318 WeakPolarHBondContact O-CB 3.48Å; Y315-Q318 PolarHBondContact O-N 2.96Å
316I98.9Very high98.8Very high0 Ų025 Ų250%012%0.123CC..Hα-helixtrans-55.7-43.3174.2-60.4163.8000110.2F77 Y79 L97 L115 T119 I121 L312 L313 Q318 V319F77-I316 HydrophobicContact CD1-CG1 4.09Å; F77-I316 HydrophobicContact CD1-CG2 4.2Å; F77-I316 HydrophobicContact CD2-CG2 4.29Å; F77-I316 HydrophobicContact CE1-CD1 4.48Å; F77-I316 HydrophobicContact CE1-CG1 3.64Å; F77-I316 HydrophobicContact CE2-CB 4.38Å; F77-I316 HydrophobicContact CE2-CG1 4.14Å; F77-I316 HydrophobicContact CG-CG2 4.08Å; F77-I316 HydrophobicContact CZ-CB 4.4Å; F77-I316 HydrophobicContact CZ-CG1 3.68Å; Y79-I316 HydrophobicContact CD2-CG1 4.45Å; Y79-I316 HydrophobicContact CE2-CD1 4Å; Y79-I316 HydrophobicContact CE2-CG1 3.74Å; L97-I316 HydrophobicContact CD2-CD1 4.18Å; L115-I316 HydrophobicContact CD1-CB 4.48Å; L115-I316 HydrophobicContact CD1-CG2 3.86Å; L115-I316 HydrophobicContact CD2-CB 4.49Å; L115-I316 HydrophobicContact CD2-CD1 4.47Å; L115-I316 HydrophobicContact CD2-CG2 4.15Å; L115-I316 HydrophobicContact CG-CG2 4.25Å; T119-I316 HydrophobicContact CG2-CG2 4.4Å; I121-I316 HydrophobicContact CD1-CD1 4.42Å; I121-I316 HydrophobicContact CD1-CG2 3.99Å; I121-I316 HydrophobicContact CG1-CG2 4.07Å; L312-I316 WeakPolarHBondContact O-CG1 3.38Å; L312-I316 PolarHBondContact O-N 2.93Å; L312-I316 VanDerWaalsContact O-N 3.16Å; L313-I316 PolarHBondContact O-N 3.2Å; I316-Q318 PolarHBondContact O-N 2.84Å; I316-Q318 VanDerWaalsContact O-N 3.1Å; I316-V319 WeakPolarHBondContact O-CB 3.39Å; I316-V319 WeakPolarHBondContact O-CG1 3.5Å; I316-V319 PolarHBondContact O-N 3.31Å; I316-V319 VanDerWaalsContact O-N 3.09Å
317Q98.6Very high98.8Very high52 Ų5218.8 Ų18.824%0.2439%0.093CC..Hα-helixtrans-58.2-25.2178.7-72.1174.1-20.400113.3L115 L313 Y315 V319 H320 Y393L115-Q317 HydrophobicContact CD1-CG 3.89Å; L313-Q317 WeakPolarHBondContact O-CG 3.48Å; L313-Q317 PolarHBondContact O-N 2.79Å; Y315-Q317 PolarHBondContact O-N 3.04Å; Q317-V319 PolarHBondContact O-N 2.94Å; Q317-H320 WeakPolarHBondContact O-CB 3.49Å; Q317-H320 PolarHBondContact O-N 3.36Å; Q317-Y393 HydrophobicContact CG-CE1 4.12Å; Q317-Y393 PolarHBondContact NE2-OH 3.38Å
318Q98.9Very high98.8Very high5 Ų518.2 Ų18.22%0.0239%0.088CC..G310 helixtrans-69.4-12.6179-58-54.8-6200113.9L193 H232 L233 V236 A314 Y315 I316 H320 L321 Y388L193-Q318 HydrophobicContact CD2-CB 3.88Å; H232-Q318 PolarHBondContact NE2-OE1 3.21Å; L233-Q318 HydrophobicContact CD2-CB 3.39Å; L233-Q318 HydrophobicContact CD2-CG 3.89Å; V236-Q318 HydrophobicContact CB-CG 4.26Å; V236-Q318 HydrophobicContact CG1-CG 3.79Å; V236-Q318 HydrophobicContact CG2-CG 4.19Å; A314-Q318 WeakPolarHBondContact O-CG 3.41Å; A314-Q318 PolarHBondContact O-NE2 3.39Å; Y315-Q318 WeakPolarHBondContact O-CB 3.48Å; Y315-Q318 PolarHBondContact O-N 2.96Å; I316-Q318 PolarHBondContact O-N 2.84Å; I316-Q318 VanDerWaalsContact O-N 3.1Å; Q318-H320 PolarHBondContact O-N 3.33Å; Q318-L321 HydrophobicContact CB-CD1 4.13Å; Q318-L321 WeakPolarHBondContact O-CB 3.33Å; Q318-L321 WeakPolarHBondContact O-CG 3.31Å; Q318-L321 PolarHBondContact O-N 2.04Å; Q318-Y388 PolarHBondContact NE2-OH 3.01Å
319V98.9Very high98.6Very high3 Ų319.3 Ų19.32%0.0189%0.094CC..G310 helixtrans-60-13.317278.90000112.5P75 F77 T119 V192 L193 I316 Q317P75-V319 HydrophobicContact CB-CG2 3.68Å; P75-V319 HydrophobicContact CG-CG1 3.9Å; P75-V319 HydrophobicContact CG-CG2 4Å; F77-V319 HydrophobicContact CB-CG2 4.33Å; F77-V319 HydrophobicContact CD2-CB 4.33Å; T119-V319 HydrophobicContact CG2-CG1 3.92Å; V192-V319 HydrophobicContact CB-CG2 3.85Å; V192-V319 HydrophobicContact CG1-CG2 4.02Å; L193-V319 HydrophobicContact CB-CB 4.05Å; L193-V319 HydrophobicContact CB-CG2 3.8Å; L193-V319 HydrophobicContact CD2-CB 4.12Å; I316-V319 WeakPolarHBondContact O-CB 3.39Å; I316-V319 WeakPolarHBondContact O-CG1 3.5Å; I316-V319 PolarHBondContact O-N 3.31Å; I316-V319 VanDerWaalsContact O-N 3.09Å; Q317-V319 PolarHBondContact O-N 2.94Å
320H98.9Very high98.1Very high0 Ų018.8 Ų18.80%010%0.102CC..G310 helixtrans-96.712.2177.2-59.4-46.3000114.2S118 T119 Q317 Q318 G389 Y393 S394 A395S118-H320 PolarHBondContact O-CE1 3.14Å; S118-H320 PolarHBondContact OG-CE1 3.45Å; S118-H320 PolarHBondContact OG-NE2 2.95Å; T119-H320 PolarHBondContact OG1-CE1 3.31Å; T119-H320 PolarHBondContact OG1-NE2 3.41Å; Q317-H320 WeakPolarHBondContact O-CB 3.49Å; Q317-H320 PolarHBondContact O-N 3.36Å; Q318-H320 PolarHBondContact O-N 3.33Å; H320-G389 CarbonylContact O-C 3.33Å; H320-G389 WeakPolarHBondContact O-CA 3.33Å; H320-Y393 VanDerWaalsContact CD2-C 3.46Å; H320-Y393 WeakPolarHBondContact CD2-CA 3.45Å; H320-Y393 PolarHBondContact CE1-O 3.15Å; H320-Y393 VanDerWaalsContact CG-C 3.41Å; H320-Y393 PolarHBondContact ND1-O 2.89Å; H320-S394 CarbonylContact O-C 3.59Å; H320-A395 WeakPolarHBondContact O-CA 3.32Å; H320-A395 PolarHBondContact O-N 3.1Å; H320-A395 VanDerWaalsContact O-N 3.11Å
321L98.9Very high97.7Very high2 Ų222.3 Ų22.31%0.0111%0.112CC..  trans-68.4158.2168.1-75.2168.6000111.9L233 Q318 L362 Y388 P390 A395L233-L321 HydrophobicContact CD2-CD1 4.15Å; Q318-L321 HydrophobicContact CB-CD1 4.13Å; Q318-L321 WeakPolarHBondContact O-CB 3.33Å; Q318-L321 WeakPolarHBondContact O-CG 3.31Å; Q318-L321 PolarHBondContact O-N 2.04Å; L321-L362 HydrophobicContact CB-CD2 4.05Å; L321-Y388 HydrophobicContact CD2-CD2 3.89Å; L321-Y388 HydrophobicContact CD2-CE2 3.75Å; L321-P390 HydrophobicContact CD2-CG 3.67Å; L321-P390 HydrophobicContact CG-CG 3.73Å; L321-A395 WeakPolarHBondContact O-CB 3.36Å
322G98.7Very high97.4Very high0 Ų024.1 Ų24.10%013%0.131CC..SBendtrans74.3-139.5166.500000115.7R361 L363 A395 M396G322-R361 VanDerWaalsContact CA-O 3.31Å; G322-R361 WeakPolarHBondContact CA-O 3.35Å; G322-L363 WeakPolarHBondContact CA-O 3.3Å; G322-L363 PolarHBondContact N-O 2.97Å; G322-L363 VanDerWaalsContact N-O 3.11Å; G322-A395 WeakPolarHBondContact O-CB 3.48Å; G322-M396 PolarHBondContact O-N 3.13Å
323V98.8Very high97.3Very high1 Ų129.8 Ų29.81%0.00616%0.158CC..EExtended strand (participates in β ladder)trans-125.8140.2-172.7-170.50000110.3Y359 R361 F370 L384 V386 M396 H398V323-Y359 HydrophobicContact CB-CE2 4.43Å; V323-Y359 HydrophobicContact CG1-CE2 4.02Å; V323-Y359 WeakPolarHBondContact CG1-OH 3.44Å; V323-R361 PolarHBondContact N-O 2.85Å; V323-R361 PolarHBondContact O-N 3.22Å; V323-F370 HydrophobicContact CB-CZ 4.03Å; V323-F370 HydrophobicContact CG2-CE2 4.17Å; V323-F370 HydrophobicContact CG2-CZ 3.8Å; V323-L384 HydrophobicContact CG1-CD1 4.06Å; V323-L384 HydrophobicContact CG2-CD1 4.4Å; V323-V386 HydrophobicContact CG2-CB 4.48Å; V323-V386 HydrophobicContact CG2-CG1 4.28Å; V323-V386 HydrophobicContact CG2-CG2 3.43Å; V323-V386 VanDerWaalsContact CG2-CG2 3.43Å; V323-M396 CarbonylContact C-O 3.55Å; V323-M396 WeakPolarHBondContact CA-O 3.46Å; V323-M396 WeakPolarHBondContact CG1-O 3.44Å; V323-M396 HydrophobicContact CG2-CB 4.4Å; V323-M396 HydrophobicContact CG2-SD 4.44Å; V323-H398 HydrophobicContact CG1-CB 3.84Å
324K98.8Very high97.2Very high8 Ų831.4 Ų31.44%0.03517%0.171CC..EExtended strand (participates in β ladder)trans-136.1159.1171.167.3-179.1172.1-178.80111.2G73 Y359 Y360 S394 A395 M396 K397 H398G73-K324 WeakPolarHBondContact O-CE 3.36Å; G73-K324 PolarHBondContact O-NZ 3.29Å; K324-Y359 VanDerWaalsContact CA-O 3.31Å; K324-Y359 WeakPolarHBondContact CA-O 3.33Å; K324-Y360 HydrophobicContact CB-CD1 3.52Å; K324-Y360 HydrophobicContact CB-CE1 3.75Å; K324-Y360 HydrophobicContact CB-CG 4.29Å; K324-Y360 HydrophobicContact CD-CD1 4.17Å; K324-Y360 HydrophobicContact CD-CE1 3.75Å; K324-Y360 HydrophobicContact CG-CD1 4.49Å; K324-Y360 HydrophobicContact CG-CE1 4.37Å; K324-S394 VanDerWaalsContact CE-OG 3.22Å; K324-S394 WeakPolarHBondContact CE-OG 2.87Å; K324-S394 PolarHBondContact NZ-OG 3.28Å; K324-A395 HydrophobicContact CB-CB 4.28Å; K324-A395 HydrophobicContact CD-CB 4.04Å; K324-A395 HydrophobicContact CG-CB 3.91Å; K324-M396 PolarHBondContact N-O 3.08Å; K324-K397 HydrophobicContact CG-CG 4.35Å; K324-K397 CarbonylContact O-C 3.59Å; K324-K397 VanDerWaalsContact O-CA 3.26Å; K324-K397 WeakPolarHBondContact O-CA 3.38Å; K324-H398 PolarHBondContact O-N 3.35Å
325G98.6Very high97.2Very high11 Ų1131.2 Ų31.211%0.11317%0.168CC..EExtended strand (participates in β ladder)trans159.9-154.7169.400000111.2E358 Y359 H398G325-E358 CarbonylContact O-C 3.51Å; G325-E358 WeakPolarHBondContact O-CA 3.17Å; G325-Y359 PolarHBondContact N-O 2.81Å; G325-Y359 VanDerWaalsContact N-O 3.11Å; G325-Y359 VanDerWaalsContact O-CD1 3.27Å; G325-Y359 WeakPolarHBondContact O-CD1 3.31Å; G325-Y359 PolarHBondContact O-N 3.39Å; G325-H398 VanDerWaalsContact CA-O 3.32Å; G325-H398 WeakPolarHBondContact CA-O 3.24Å
326Q98.7Very high97.1Very high39 Ų3935.9 Ų35.918%0.18219%0.19CC..EExtended strand (participates in β ladder)trans-124147.5-175.1-67.8177-79.500112.1V72 F328 H356 G357 E358 N399 F400V72-Q326 HydrophobicContact CG1-CG 4.25Å; Q326-F328 HydrophobicContact CB-CD2 4.27Å; Q326-F328 HydrophobicContact CB-CE1 4.29Å; Q326-F328 HydrophobicContact CB-CE2 3.53Å; Q326-F328 HydrophobicContact CB-CZ 3.54Å; Q326-F328 HydrophobicContact CG-CZ 4.26Å; Q326-H356 PolarHBondContact NE2-O 2.81Å; Q326-G357 CarbonylContact C-O 3.47Å; Q326-G357 VanDerWaalsContact CA-O 3.22Å; Q326-G357 WeakPolarHBondContact CA-O 3.41Å; Q326-E358 HydrophobicContact CG-CB 4.47Å; Q326-E358 HydrophobicContact CG-CG 3.69Å; Q326-N399 PolarHBondContact N-OD1 3.06Å; Q326-N399 CarbonylContact O-C 3.34Å; Q326-N399 WeakPolarHBondContact O-CA 3.39Å; Q326-N399 WeakPolarHBondContact O-CB 3.36Å; Q326-F400 PolarHBondContact O-N 2.98Å
327V98.8Very high97Very high0 Ų039.8 Ų39.80%021%0.211CC..EExtended strand (participates in β ladder)trans-97.8126.5167.8-176.10000108.6P334 V335 A338 V340 T353 G357 Y359 V372 F400 L402V327-P334 WeakPolarHBondContact O-CA 3.34Å; V327-V335 HydrophobicContact CG1-CB 4.22Å; V327-V335 PolarHBondContact O-N 3.15Å; V327-A338 HydrophobicContact CB-CB 4.24Å; V327-A338 HydrophobicContact CG1-CB 3.95Å; V327-A338 HydrophobicContact CG2-CB 4.32Å; V327-V340 HydrophobicContact CG2-CG2 3.84Å; V327-T353 HydrophobicContact CB-CG2 3.94Å; V327-T353 HydrophobicContact CG2-CG2 3.45Å; V327-T353 VanDerWaalsContact CG2-CG2 3.45Å; V327-G357 PolarHBondContact N-O 3.35Å; V327-Y359 HydrophobicContact CG2-CD1 4.17Å; V327-V372 HydrophobicContact CG1-CG1 4.08Å; V327-V372 HydrophobicContact CG2-CG1 4.05Å; V327-F400 CarbonylContact C-O 3.54Å; V327-F400 WeakPolarHBondContact CA-O 3.46Å; V327-F400 HydrophobicContact CG1-CB 4.46Å; V327-F400 HydrophobicContact CG2-CB 4.23Å; V327-F400 HydrophobicContact CG2-CD2 4.25Å; V327-L402 HydrophobicContact CG1-CD1 3.74Å; V327-L402 HydrophobicContact CG1-CG 3.82Å
328F98.1Very high96.9Very high42 Ų4237.3 Ų37.318%0.18420%0.199CC..EExtended strand (participates in β ladder)trans-115.6152.1177.7-61.1-79.3000111.5Q326 G332 M333 P334 N399 F400 K401 L402Q326-F328 HydrophobicContact CB-CD2 4.27Å; Q326-F328 HydrophobicContact CB-CE1 4.29Å; Q326-F328 HydrophobicContact CB-CE2 3.53Å; Q326-F328 HydrophobicContact CB-CZ 3.54Å; Q326-F328 HydrophobicContact CG-CZ 4.26Å; F328-G332 VanDerWaalsContact CD1-O 3.31Å; F328-G332 WeakPolarHBondContact CD1-O 3.41Å; F328-M333 CarbonylContact C-O 3.5Å; F328-M333 VanDerWaalsContact CA-O 3.27Å; F328-M333 WeakPolarHBondContact CA-O 3.24Å; F328-P334 HydrophobicContact CD1-CB 4.43Å; F328-P334 HydrophobicContact CE1-CB 4.34Å; F328-N399 HydrophobicContact CD2-CB 4.2Å; F328-N399 HydrophobicContact CE2-CB 3.94Å; F328-F400 PolarHBondContact N-O 3.12Å; F328-K401 CarbonylContact O-C 3.49Å; F328-K401 WeakPolarHBondContact O-CA 3.1Å; F328-L402 PolarHBondContact O-N 3.09Å
329D94.3Very high96.9Very high23 Ų2337.3 Ų37.312%0.12320%0.2CC..  trans-82-176.9169.877.5-1.8000112.2W331 G332 M333 V335 K401D329-W331 PolarHBondContact O-N 2.95Å; D329-W331 VanDerWaalsContact O-N 3.16Å; D329-W331 WeakPolarHBondContact OD1-CA 3.42Å; D329-W331 WeakPolarHBondContact OD1-CB 3.34Å; D329-W331 PolarHBondContact OD1-N 3.23Å; D329-G332 PolarHBondContact O-N 2.63Å; D329-G332 VanDerWaalsContact O-N 3.07Å; D329-G332 PolarHBondContact OD1-N 3.45Å; D329-M333 PolarHBondContact N-O 2.82Å; D329-M333 PolarHBondContact OD1-N 2.7Å; D329-V335 HydrophobicContact CB-CG2 3.81Å; D329-K401 VanDerWaalsContact O-CE 3.3Å; D329-K401 WeakPolarHBondContact O-CE 3.12Å
330G89.8Confident96.8Very high38 Ų3837.2 Ų37.239%0.39220%0.199SC..THydrogen-bonded Turntrans-58-27.317800000114.1K401 L402G330-K401 WeakPolarHBondContact O-CE 3.36Å; G330-K401 PolarHBondContact O-NZ 3.07Å; G330-L402 PolarHBondContact N-O 2.9Å
331W90.3Very high96.7Very high208 Ų20840.3 Ų40.379%0.78821%0.214SC*.THydrogen-bonded Turntrans-90.9-3.5-179.3-55.1109.2000113.3D329D329-W331 PolarHBondContact O-N 2.95Å; D329-W331 VanDerWaalsContact O-N 3.16Å; D329-W331 WeakPolarHBondContact OD1-CA 3.42Å; D329-W331 WeakPolarHBondContact OD1-CB 3.34Å; D329-W331 PolarHBondContact OD1-N 3.23Å
332G92.8Very high96.6Very high39 Ų3940.4 Ų40.440%0.40221%0.214SC..SBendtrans83.415.3-178.200000113.8F328 D329F328-G332 VanDerWaalsContact CD1-O 3.31Å; F328-G332 WeakPolarHBondContact CD1-O 3.41Å; D329-G332 PolarHBondContact O-N 2.63Å; D329-G332 VanDerWaalsContact O-N 3.07Å; D329-G332 PolarHBondContact OD1-N 3.45Å
333M96.1Very high96.5Very high118 Ų11845.6 Ų45.658%0.58124%0.239SC*.  trans-85.6138.1175-65-61.2-65.700110.5F328 D329F328-M333 CarbonylContact C-O 3.5Å; F328-M333 VanDerWaalsContact CA-O 3.27Å; F328-M333 WeakPolarHBondContact CA-O 3.24Å; D329-M333 PolarHBondContact N-O 2.82Å; D329-M333 PolarHBondContact OD1-N 2.7Å
334P97.6Very high96.3Very high59 Ų5949 Ų4938%0.38327%0.274SS..BIsolated β-bridgetrans-64.2136.6177.726-33.2000111V327 F328 H356V327-P334 WeakPolarHBondContact O-CA 3.34Å; F328-P334 HydrophobicContact CD1-CB 4.43Å; F328-P334 HydrophobicContact CE1-CB 4.34Å; P334-H356 VanDerWaalsContact CB-O 3.26Å; P334-H356 WeakPolarHBondContact CB-O 3.1Å
335V97.8Very high96.1Very high8 Ų849.6 Ų49.65%0.04828%0.276CS..  trans-104.3110.4-176.7-178.40000109.6V327 D329 A338 T353 G357 Y374V327-V335 HydrophobicContact CG1-CB 4.22Å; V327-V335 PolarHBondContact O-N 3.15Å; D329-V335 HydrophobicContact CB-CG2 3.81Å; V335-A338 HydrophobicContact CB-CB 4.44Å; V335-A338 HydrophobicContact CG1-CB 3.91Å; V335-T353 WeakPolarHBondContact O-CB 3.45Å; V335-T353 PolarHBondContact O-OG1 2.89Å; V335-G357 VanDerWaalsContact O-CA 3.31Å; V335-G357 WeakPolarHBondContact O-CA 3.38Å; V335-Y374 HydrophobicContact CG1-CD1 3.61Å; V335-Y374 HydrophobicContact CG1-CD2 3.57Å; V335-Y374 HydrophobicContact CG1-CE1 3.69Å; V335-Y374 HydrophobicContact CG1-CE2 3.62Å; V335-Y374 HydrophobicContact CG1-CG 3.58Å
336Q97.3Very high95.7Very high97 Ų9759.6 Ų59.645%0.45331%0.31SS..THydrogen-bonded Turntrans-75.1146.3170.2-179178.92000111.1A338 N354 Y374Q336-A338 PolarHBondContact O-N 2.79Å; Q336-N354 WeakPolarHBondContact CA-O 2.97Å; Q336-N354 WeakPolarHBondContact CG-O 2.92Å; Q336-Y374 WeakPolarHBondContact O-CE2 3.33Å
337N96.4Very high95.3Very high83 Ų8358.6 Ų58.644%0.44431%0.306SS..THydrogen-bonded Turntrans64.415.9177.2-63.6-37.8000115.9R352 T353N337-R352 PolarHBondContact O-NH1 2.74Å; N337-T353 PolarHBondContact N-O 2.68Å; N337-T353 PolarHBondContact N-OG1 3.33Å
338A97.8Very high94.9Very high0 Ų062.4 Ų62.40%033%0.325CS..  trans-64.9133.6165.800000109.5V327 V335 Q336 R352 T353 Y374V327-A338 HydrophobicContact CB-CB 4.24Å; V327-A338 HydrophobicContact CG1-CB 3.95Å; V327-A338 HydrophobicContact CG2-CB 4.32Å; V335-A338 HydrophobicContact CB-CB 4.44Å; V335-A338 HydrophobicContact CG1-CB 3.91Å; Q336-A338 PolarHBondContact O-N 2.79Å; A338-R352 CarbonylContact O-C 3.58Å; A338-R352 WeakPolarHBondContact O-CA 3.23Å; A338-T353 HydrophobicContact CB-CG2 4.13Å; A338-T353 PolarHBondContact N-OG1 3.05Å; A338-T353 PolarHBondContact O-N 3.17Å; A338-Y374 HydrophobicContact CB-CD2 4.21Å; A338-Y374 HydrophobicContact CB-CG 4.47Å
339V97.9Very high94.6Very high5 Ų561 Ų613%0.0332%0.32CS..EExtended strand (participates in β ladder)trans-79.6128.6176.4173.90000108.5E341 P350 F351 R352 V372 S373V339-E341 HydrophobicContact CG1-CG 3.61Å; V339-P350 HydrophobicContact CG1-CB 3.88Å; V339-F351 WeakPolarHBondContact CA-O 3.43Å; V339-R352 HydrophobicContact CG2-CG 4.15Å; V339-V372 CarbonylContact O-C 3.54Å; V339-V372 VanDerWaalsContact O-CA 3.25Å; V339-V372 WeakPolarHBondContact O-CA 3.19Å; V339-S373 PolarHBondContact N-O 2.96Å; V339-S373 PolarHBondContact O-N 3.4Å
340V97.7Very high94.5Very high1 Ų160.1 Ų60.11%0.00632%0.316CS..EExtended strand (participates in β ladder)trans-123.593.8178.7-1760000108.5V327 F351 T353 Y359 F370 V372 F400V327-V340 HydrophobicContact CG2-CG2 3.84Å; V340-F351 PolarHBondContact N-O 2.78Å; V340-T353 HydrophobicContact CG2-CG2 3.99Å; V340-Y359 HydrophobicContact CB-CD2 4.46Å; V340-Y359 HydrophobicContact CB-CG 4.35Å; V340-Y359 HydrophobicContact CG1-CD2 3.7Å; V340-Y359 HydrophobicContact CG1-CE2 4.06Å; V340-Y359 HydrophobicContact CG1-CG 3.98Å; V340-Y359 HydrophobicContact CG2-CD1 4.35Å; V340-Y359 HydrophobicContact CG2-CG 4.06Å; V340-F370 HydrophobicContact CG1-CD1 3.96Å; V340-F370 HydrophobicContact CG1-CE1 4.36Å; V340-V372 HydrophobicContact CG1-CG2 4.34Å; V340-V372 HydrophobicContact CG2-CG1 4.18Å; V340-F400 HydrophobicContact CG1-CE2 4.03Å
341E95.2Very high94.8Very high65 Ų6558.8 Ų58.830%0.30430%0.299SS..EExtended strand (participates in β ladder)trans-106.2153-176.8-75.3179.1130.500112V339 P350 F370 K371V339-E341 HydrophobicContact CG1-CG 3.61Å; E341-P350 HydrophobicContact CG-CB 4.41Å; E341-F370 CarbonylContact O-C 3.38Å; E341-F370 VanDerWaalsContact O-CA 3.29Å; E341-F370 WeakPolarHBondContact O-CA 3.36Å; E341-K371 PolarHBondContact N-O 2.71Å; E341-K371 PolarHBondContact O-N 3.39Å
342V97.8Very high95.1Very high4 Ų451.8 Ų51.82%0.02427%0.273CS..EExtended strand (participates in β ladder)trans-107.5127.2172.3178.20000107.8G344 R345 L363 Y368 F370V342-G344 PolarHBondContact O-N 2.86Å; V342-R345 HydrophobicContact CB-CB 4.23Å; V342-R345 HydrophobicContact CB-CG 4.18Å; V342-R345 HydrophobicContact CG1-CG 4.14Å; V342-R345 PolarHBondContact O-N 3.33Å; V342-L363 HydrophobicContact CG2-CD1 4.1Å; V342-L363 HydrophobicContact CG2-CD2 4.35Å; V342-Y368 HydrophobicContact CG1-CD1 3.65Å; V342-Y368 HydrophobicContact CG1-CG 4.25Å; V342-F370 HydrophobicContact CG2-CD1 3.97Å; V342-F370 HydrophobicContact CG2-CE1 3.63Å; V342-F370 HydrophobicContact CG2-CE2 4.47Å; V342-F370 HydrophobicContact CG2-CZ 3.91Å
343E96.3Very high95.4Very high109 Ų10950.1 Ų50.151%0.50925%0.254SS..THydrogen-bonded Turntrans-56.9131.2178.3-175.2156.5-130.400111R345 T369 K371E343-R345 VanDerWaalsContact C-N 3.34Å; E343-T369 PolarHBondContact N-O 2.94Å; E343-K371 IonicContact OE1-NZ 3.2Å; E343-K371 PolarHBondContact OE1-NZ 3.34Å
344G93.8Very high95.4Very high73 Ų7345.5 Ų45.575%0.75323%0.232SC*.THydrogen-bonded Turntrans89.5-14.1-173.200000114.9V342V342-G344 PolarHBondContact O-N 2.86Å
345R94.9Very high95.4Very high20 Ų2049.1 Ų49.18%0.07524%0.244CC..  trans-107.881.8178.7-56.3-165.4-179.6-115-15.7111.3P225 D226 D228 V342 E343 N347 L363P225-R345 HydrophobicContact CB-CB 4.36Å; D226-R345 WeakPolarHBondContact OD1-CD 3.33Å; D226-R345 IonicContact OD1-CZ 2.78Å; D226-R345 IonicContact OD1-NE 3.32Å; D226-R345 IonicContact OD1-NH1 2.78Å; D226-R345 PolarHBondContact OD1-NH1 2.87Å; D228-R345 IonicContact OD1-CZ 2.87Å; D228-R345 VanDerWaalsContact OD1-CZ 3.28Å; D228-R345 IonicContact OD1-NH1 3.21Å; D228-R345 PolarHBondContact OD1-NH1 3.4Å; D228-R345 IonicContact OD1-NH2 3.77Å; D228-R345 PolarHBondContact OD1-NH2 3.2Å; D228-R345 IonicContact OD2-CZ 2.79Å; D228-R345 IonicContact OD2-NH1 3.07Å; D228-R345 IonicContact OD2-NH2 3.58Å; D228-R345 PolarHBondContact OD2-NH2 2.86Å; V342-R345 HydrophobicContact CB-CB 4.23Å; V342-R345 HydrophobicContact CB-CG 4.18Å; V342-R345 HydrophobicContact CG1-CG 4.14Å; V342-R345 PolarHBondContact O-N 3.33Å; E343-R345 VanDerWaalsContact C-N 3.34Å; R345-N347 PolarHBondContact O-N 3.09Å; R345-N347 PolarHBondContact O-OD1 2.91Å; R345-L363 VanDerWaalsContact NE-CD2 3.33Å
346R90.3Very high95.3Very high221 Ų22151.8 Ų51.883%0.83426%0.256SS*.  trans-85.685.2179.7-65.3-175.9-175.2-179.21.5110.9P225P225-R346 WeakPolarHBondContact CG-O 3.26Å
347N91.2Very high95.4Very high17 Ų1747.2 Ų47.29%0.09123%0.234CC..  trans-64142.2172.8-5995.5000110.6D226 Y278 R345 C349 F351D226-N347 PolarHBondContact OD2-ND2 2.86Å; D226-N347 VanDerWaalsContact OD2-ND2 3.09Å; Y278-N347 VanDerWaalsContact CZ-ND2 3.3Å; Y278-N347 PolarHBondContact OH-ND2 3.41Å; R345-N347 PolarHBondContact O-N 3.09Å; R345-N347 PolarHBondContact O-OD1 2.91Å; N347-C349 WeakPolarHBondContact CB-O 3.14Å; N347-C349 PolarHBondContact O-N 3.18Å; N347-C349 VanDerWaalsContact O-N 3.17Å; N347-F351 HydrophobicContact CB-CD2 4.43Å
348M90.1Very high95.5Very high80 Ų8043.3 Ų43.339%0.39421%0.214SC..SBendtrans-54.9-35174.8-66.7-177.3177.200111.5A160 F161 Y208 V279A160-M348 HydrophobicContact CB-SD 3.7Å; F161-M348 HydrophobicContact CD1-CE 4.06Å; F161-M348 HydrophobicContact CE1-CE 3.3Å; F161-M348 HydrophobicContact CE2-CE 4.12Å; F161-M348 HydrophobicContact CZ-CE 3.35Å; Y208-M348 HydrophobicContact CE1-CE 4.49Å; Y208-M348 HydrophobicContact CE2-CE 4.3Å; V279-M348 HydrophobicContact CG1-CB 4.33Å; V279-M348 HydrophobicContact CG2-SD 4.05Å
349C91Very high95.5Very high12 Ų1243.6 Ų43.68%0.08122%0.215CC..SBendtrans-122.4119175.3-100.90000108.8V279 N347 C420V279-C349 HydrophobicContact CG1-CB 4.36Å; V279-C349 WeakPolarHBondContact O-CB 3.21Å; N347-C349 WeakPolarHBondContact CB-O 3.14Å; N347-C349 PolarHBondContact O-N 3.18Å; N347-C349 VanDerWaalsContact O-N 3.17Å; C349-C420 WeakPolarHBondContact CA-SG 3.33Å; C349-C420 HydrophobicContact CB-CB 4.27Å; C349-C420 WeakPolarHBondContact CB-SG 3.26Å; C349-C420 WeakPolarHBondContact SG-CB 3.48Å; C349-C420 CovalentContact SG-SG 2.02Å; C349-C420 PolarHBondContact SG-SG 3.46Å
350P93.3Very high95.5Very high6 Ų644.3 Ų44.34%0.03922%0.217CC..  trans-68.3139.3-175.626.3-34.2000110.9V339 E341V339-P350 HydrophobicContact CG1-CB 3.88Å; E341-P350 HydrophobicContact CG-CB 4.41Å
351F95.8Very high95.6Very high9 Ų944.4 Ų44.44%0.03922%0.217CC..  trans-69134176.7-84.9-129000110.4Y278 Q282 L284 V339 V340 N347 R361Y278-F351 HydrophobicContact CE2-CE2 4.48Å; Y278-F351 HydrophobicContact CE2-CZ 4.45Å; Q282-F351 HydrophobicContact CB-CD1 3.88Å; Q282-F351 HydrophobicContact CB-CD2 4.41Å; Q282-F351 HydrophobicContact CB-CE1 3.74Å; Q282-F351 HydrophobicContact CB-CE2 4.26Å; Q282-F351 HydrophobicContact CB-CG 4.23Å; Q282-F351 HydrophobicContact CB-CZ 3.93Å; Q282-F351 HydrophobicContact CG-CD1 4.5Å; Q282-F351 HydrophobicContact CG-CD2 4.45Å; Q282-F351 HydrophobicContact CG-CG 4.38Å; Q282-F351 WeakPolarHBondContact O-CE1 3.33Å; L284-F351 HydrophobicContact CD1-CZ 4.18Å; V339-F351 WeakPolarHBondContact CA-O 3.43Å; V340-F351 PolarHBondContact N-O 2.78Å; N347-F351 HydrophobicContact CB-CD2 4.43Å; F351-R361 VanDerWaalsContact CE1-NH1 3.26Å
352R97.1Very high95.7Very high62 Ų6241.6 Ų41.623%0.23420%0.204CC..BIsolated β-bridgetrans-127.5152.8-175-68.8174.1-175-82.2-2.4111.9Q282 N337 A338 V339Q282-R352 PolarHBondContact NE2-O 3.09Å; N337-R352 PolarHBondContact O-NH1 2.74Å; A338-R352 CarbonylContact O-C 3.58Å; A338-R352 WeakPolarHBondContact O-CA 3.23Å; V339-R352 HydrophobicContact CG2-CG 4.15Å
353T98.4Very high95.8Very high3 Ų341.4 Ų41.42%0.01820%0.203CC..  trans-69.2144.3172.853.60000112.9V327 V335 N337 A338 V340 G357 E358V327-T353 HydrophobicContact CB-CG2 3.94Å; V327-T353 HydrophobicContact CG2-CG2 3.45Å; V327-T353 VanDerWaalsContact CG2-CG2 3.45Å; V335-T353 WeakPolarHBondContact O-CB 3.45Å; V335-T353 PolarHBondContact O-OG1 2.89Å; N337-T353 PolarHBondContact N-O 2.68Å; N337-T353 PolarHBondContact N-OG1 3.33Å; A338-T353 HydrophobicContact CB-CG2 4.13Å; A338-T353 PolarHBondContact N-OG1 3.05Å; A338-T353 PolarHBondContact O-N 3.17Å; V340-T353 HydrophobicContact CG2-CG2 3.99Å; T353-G357 VanDerWaalsContact CG2-O 3.26Å; T353-G357 WeakPolarHBondContact CG2-O 3.42Å; T353-E358 CarbonylContact C-O 3.43Å; T353-E358 WeakPolarHBondContact CA-O 3.19Å; T353-E358 WeakPolarHBondContact CB-O 3.23Å
354N96.8Very high95.9Very high21 Ų2137.8 Ų37.811%0.11219%0.187CC..  trans-75.7-174.6175.875.86.2000112.3T190 Q336 H356 G357 E358T190-N354 HydrophobicContact CG2-CB 4.27Å; T190-N354 WeakPolarHBondContact OG1-CB 3.18Å; T190-N354 PolarHBondContact OG1-ND2 2.94Å; T190-N354 VanDerWaalsContact OG1-ND2 3.11Å; Q336-N354 WeakPolarHBondContact CA-O 2.97Å; Q336-N354 WeakPolarHBondContact CG-O 2.92Å; N354-H356 PolarHBondContact O-N 3.16Å; N354-H356 VanDerWaalsContact O-N 3.15Å; N354-H356 WeakPolarHBondContact OD1-CA 3.27Å; N354-H356 WeakPolarHBondContact OD1-CB 3.32Å; N354-H356 PolarHBondContact OD1-N 2.94Å; N354-G357 WeakPolarHBondContact O-CA 3.4Å; N354-G357 PolarHBondContact O-N 2.91Å; N354-G357 PolarHBondContact OD1-N 2.79Å; N354-E358 PolarHBondContact N-O 3.32Å; N354-E358 PolarHBondContact ND2-OE2 2.96Å; N354-E358 WeakPolarHBondContact OD1-CB 3.47Å; N354-E358 PolarHBondContact OD1-N 3.07Å
355Q95.8Very high96.1Very high135 Ų13537.8 Ų37.863%0.63117%0.174SC*.THydrogen-bonded Turntrans-60.7-20.2179.169.6-176.61.900115G357Q355-G357 VanDerWaalsContact C-N 3.34Å
356H97.2Very high96.3Very high65 Ų6538.1 Ų38.130%0.30118%0.184SC..THydrogen-bonded Turntrans-95.28.3175.2-58.3-60.1000112.3H70 V72 Q326 P334 N354 E358H70-H356 AromaticContact CD2-CD2 3.72Å; V72-H356 HydrophobicContact CG2-CB 3.97Å; Q326-H356 PolarHBondContact NE2-O 2.81Å; P334-H356 VanDerWaalsContact CB-O 3.26Å; P334-H356 WeakPolarHBondContact CB-O 3.1Å; N354-H356 PolarHBondContact O-N 3.16Å; N354-H356 VanDerWaalsContact O-N 3.15Å; N354-H356 WeakPolarHBondContact OD1-CA 3.27Å; N354-H356 WeakPolarHBondContact OD1-CB 3.32Å; N354-H356 PolarHBondContact OD1-N 2.94Å; H356-E358 HydrophobicContact CB-CG 4.14Å; H356-E358 WeakPolarHBondContact CB-OE2 3.33Å; H356-E358 IonicContact CD2-OE2 2.73Å; H356-E358 PolarHBondContact O-N 2.72Å
357G98.2Very high96.7Very high0 Ų033.3 Ų33.30%017%0.174CC..SBendtrans71.112-175.200000113.6Q326 V327 V335 T353 N354 Q355Q326-G357 CarbonylContact C-O 3.47Å; Q326-G357 VanDerWaalsContact CA-O 3.22Å; Q326-G357 WeakPolarHBondContact CA-O 3.41Å; V327-G357 PolarHBondContact N-O 3.35Å; V335-G357 VanDerWaalsContact O-CA 3.31Å; V335-G357 WeakPolarHBondContact O-CA 3.38Å; T353-G357 VanDerWaalsContact CG2-O 3.26Å; T353-G357 WeakPolarHBondContact CG2-O 3.42Å; N354-G357 WeakPolarHBondContact O-CA 3.4Å; N354-G357 PolarHBondContact O-N 2.91Å; N354-G357 PolarHBondContact OD1-N 2.79Å; Q355-G357 VanDerWaalsContact C-N 3.34Å
358E98.1Very high97Very high2 Ų234.1 Ų34.11%0.00918%0.176CC..EExtended strand (participates in β ladder)trans-81.6145.9-176.9-63.8169.993.200112.6H70 V72 G73 G325 Q326 T353 N354 H356 Y360H70-E358 IonicContact CD2-OE2 3.42Å; H70-E358 IonicContact CE1-OE1 3.68Å; H70-E358 IonicContact CE1-OE2 2.71Å; H70-E358 IonicContact NE2-OE1 2.94Å; H70-E358 IonicContact NE2-OE2 3.74Å; H70-E358 PolarHBondContact NE2-OE2 3.17Å; V72-E358 VanDerWaalsContact CA-OE1 3.25Å; V72-E358 WeakPolarHBondContact CA-OE1 3.33Å; V72-E358 HydrophobicContact CG1-CG 3.95Å; G73-E358 PolarHBondContact N-OE1 3.06Å; G325-E358 CarbonylContact O-C 3.51Å; G325-E358 WeakPolarHBondContact O-CA 3.17Å; Q326-E358 HydrophobicContact CG-CB 4.47Å; Q326-E358 HydrophobicContact CG-CG 3.69Å; T353-E358 CarbonylContact C-O 3.43Å; T353-E358 WeakPolarHBondContact CA-O 3.19Å; T353-E358 WeakPolarHBondContact CB-O 3.23Å; N354-E358 PolarHBondContact N-O 3.32Å; N354-E358 PolarHBondContact ND2-OE2 2.96Å; N354-E358 WeakPolarHBondContact OD1-CB 3.47Å; N354-E358 PolarHBondContact OD1-N 3.07Å; H356-E358 HydrophobicContact CB-CG 4.14Å; H356-E358 WeakPolarHBondContact CB-OE2 3.33Å; H356-E358 IonicContact CD2-OE2 2.73Å; H356-E358 PolarHBondContact O-N 2.72Å; E358-Y360 HydrophobicContact CB-CE2 4.01Å; E358-Y360 PolarHBondContact OE1-OH 3.29Å
359Y98.6Very high97.4Very high6 Ų631.9 Ų31.92%0.02417%0.167CC..EExtended strand (participates in β ladder)trans-128.7152167.672.9-82.4000110.4V323 K324 G325 V327 V340 R361 F370 H398 F400V323-Y359 HydrophobicContact CB-CE2 4.43Å; V323-Y359 HydrophobicContact CG1-CE2 4.02Å; V323-Y359 WeakPolarHBondContact CG1-OH 3.44Å; K324-Y359 VanDerWaalsContact CA-O 3.31Å; K324-Y359 WeakPolarHBondContact CA-O 3.33Å; G325-Y359 PolarHBondContact N-O 2.81Å; G325-Y359 VanDerWaalsContact N-O 3.11Å; G325-Y359 VanDerWaalsContact O-CD1 3.27Å; G325-Y359 WeakPolarHBondContact O-CD1 3.31Å; G325-Y359 PolarHBondContact O-N 3.39Å; V327-Y359 HydrophobicContact CG2-CD1 4.17Å; V340-Y359 HydrophobicContact CB-CD2 4.46Å; V340-Y359 HydrophobicContact CB-CG 4.35Å; V340-Y359 HydrophobicContact CG1-CD2 3.7Å; V340-Y359 HydrophobicContact CG1-CE2 4.06Å; V340-Y359 HydrophobicContact CG1-CG 3.98Å; V340-Y359 HydrophobicContact CG2-CD1 4.35Å; V340-Y359 HydrophobicContact CG2-CG 4.06Å; Y359-R361 HydrophobicContact CD2-CG 4.3Å; Y359-F370 HydrophobicContact CE2-CE1 4.45Å; Y359-H398 WeakPolarHBondContact CE1-O 3.22Å; Y359-H398 PolarHBondContact OH-O 2.86Å; Y359-F400 HydrophobicContact CD1-CD2 4.35Å; Y359-F400 AromaticContact CE1-CD2 3.56Å; Y359-F400 HydrophobicContact CE1-CD2 3.56Å; Y359-F400 AromaticContact CE1-CE2 3.71Å; Y359-F400 HydrophobicContact CE1-CE2 3.71Å; Y359-F400 AromaticContact CE2-CE2 3.91Å; Y359-F400 HydrophobicContact CE2-CE2 3.91Å; Y359-F400 AromaticContact CZ-CD2 3.69Å; Y359-F400 AromaticContact CZ-CE2 3.3Å; Y359-F400 WeakPolarHBondContact OH-CE2 3.08Å
360Y98.6Very high97.8Very high19 Ų1931.3 Ų31.38%0.07516%0.163CC..EExtended strand (participates in β ladder)trans-133.5127.1172.5-62.9-95.6000107.7G73 P75 T190 V192 K324 E358G73-Y360 WeakPolarHBondContact CA-OH 3.39Å; G73-Y360 PolarHBondContact N-OH 3.08Å; P75-Y360 HydrophobicContact CB-CD1 4.07Å; P75-Y360 HydrophobicContact CB-CE1 3.8Å; T190-Y360 HydrophobicContact CG2-CD2 4.28Å; V192-Y360 HydrophobicContact CG1-CG 4.43Å; V192-Y360 HydrophobicContact CG2-CD1 3.83Å; V192-Y360 HydrophobicContact CG2-CD2 3.84Å; V192-Y360 HydrophobicContact CG2-CE1 4.47Å; V192-Y360 HydrophobicContact CG2-CG 3.49Å; V192-Y360 VanDerWaalsContact CG2-CG 3.49Å; K324-Y360 HydrophobicContact CB-CD1 3.52Å; K324-Y360 HydrophobicContact CB-CE1 3.75Å; K324-Y360 HydrophobicContact CB-CG 4.29Å; K324-Y360 HydrophobicContact CD-CD1 4.17Å; K324-Y360 HydrophobicContact CD-CE1 3.75Å; K324-Y360 HydrophobicContact CG-CD1 4.49Å; K324-Y360 HydrophobicContact CG-CE1 4.37Å; E358-Y360 HydrophobicContact CB-CE2 4.01Å; E358-Y360 PolarHBondContact OE1-OH 3.29Å
361R98.3Very high98Very high3 Ų334.6 Ų34.61%0.01118%0.177CC..EExtended strand (participates in β ladder)trans-130.8103.3176.7-76.1-60.3-54.6173.22.2108.7D226 G322 V323 F351 Y359 L363 F370D226-R361 VanDerWaalsContact CG-NH2 3.3Å; D226-R361 IonicContact OD1-CZ 3.52Å; D226-R361 IonicContact OD1-NH2 3.78Å; D226-R361 PolarHBondContact OD1-NH2 2.84Å; D226-R361 IonicContact OD2-CZ 4Å; D226-R361 IonicContact OD2-NH1 3.51Å; D226-R361 IonicContact OD2-NH2 2.7Å; D226-R361 PolarHBondContact OD2-NH2 2.93Å; G322-R361 VanDerWaalsContact CA-O 3.31Å; G322-R361 WeakPolarHBondContact CA-O 3.35Å; V323-R361 PolarHBondContact N-O 2.85Å; V323-R361 PolarHBondContact O-N 3.22Å; F351-R361 VanDerWaalsContact CE1-NH1 3.26Å; Y359-R361 HydrophobicContact CD2-CG 4.3Å; R361-L363 HydrophobicContact CB-CD1 4.49Å; R361-L363 PolarHBondContact O-N 3.11Å; R361-F370 HydrophobicContact CB-CE1 4.27Å; R361-F370 HydrophobicContact CG-CE1 4.18Å
362L98.8Very high98.1Very high6 Ų634.2 Ų34.23%0.03118%0.175CC..  trans-68.1123.1172.3-59.3-179.8000108.6V192 L193 V229 L284 L321V192-L362 HydrophobicContact CG1-CD1 4.16Å; V192-L362 HydrophobicContact CG1-CD2 3.78Å; V192-L362 HydrophobicContact CG1-CG 3.9Å; L193-L362 HydrophobicContact CB-CD1 4.15Å; L193-L362 HydrophobicContact CD1-CD1 4Å; V229-L362 HydrophobicContact CG1-CB 4.09Å; L284-L362 HydrophobicContact CB-CD1 4.18Å; L284-L362 HydrophobicContact CD1-CD1 4.3Å; L284-L362 HydrophobicContact CD2-CB 4.32Å; L284-L362 HydrophobicContact CD2-CD1 4.11Å; L284-L362 HydrophobicContact CG-CD1 4.42Å; L321-L362 HydrophobicContact CB-CD2 4.05Å
363L98.8Very high98.1Very high0 Ų032.7 Ų32.70%017%0.174CC..  trans-145.7147.8-178.5-63.6170.7000108G322 V342 R345 R361 Y368 F370 V386G322-L363 WeakPolarHBondContact CA-O 3.3Å; G322-L363 PolarHBondContact N-O 2.97Å; G322-L363 VanDerWaalsContact N-O 3.11Å; V342-L363 HydrophobicContact CG2-CD1 4.1Å; V342-L363 HydrophobicContact CG2-CD2 4.35Å; R345-L363 VanDerWaalsContact NE-CD2 3.33Å; R361-L363 HydrophobicContact CB-CD1 4.49Å; R361-L363 PolarHBondContact O-N 3.11Å; L363-Y368 HydrophobicContact CB-CD2 4.5Å; L363-Y368 HydrophobicContact CB-CE2 3.98Å; L363-Y368 HydrophobicContact CD1-CD1 4.17Å; L363-Y368 HydrophobicContact CD1-CD2 3.94Å; L363-Y368 HydrophobicContact CD1-CE1 4.46Å; L363-Y368 HydrophobicContact CD1-CE2 4.24Å; L363-Y368 HydrophobicContact CD1-CG 3.88Å; L363-Y368 HydrophobicContact CD2-CD1 4.19Å; L363-Y368 HydrophobicContact CD2-CE1 3.92Å; L363-F370 HydrophobicContact CD1-CE2 4.24Å; L363-F370 HydrophobicContact CD1-CZ 3.65Å; L363-V386 HydrophobicContact CB-CG1 4.44Å; L363-V386 HydrophobicContact CD1-CG2 4.41Å
364L98.8Very high98Very high34 Ų3436.5 Ų36.518%0.17819%0.189CC..  trans-72.6167.2170-61.1-174.9000110.7D228 V229 H232 G366 Y368D228-L364 HydrophobicContact CB-CD1 4.2Å; V229-L364 HydrophobicContact CG2-CG 4.15Å; H232-L364 HydrophobicContact CB-CD1 4.18Å; H232-L364 HydrophobicContact CB-CD2 3.64Å; H232-L364 HydrophobicContact CB-CG 4.49Å; H232-L364 VanDerWaalsContact CG-CD2 3.45Å; L364-G366 PolarHBondContact O-N 3.05Å; L364-Y368 VanDerWaalsContact O-CE2 3.23Å; L364-Y368 WeakPolarHBondContact O-CE2 3.47Å; L364-Y368 PolarHBondContact O-OH 2.94Å; L364-Y368 VanDerWaalsContact O-OH 3.09Å
365P98.8Very high97.8Very high73 Ų7340.5 Ų40.547%0.47422%0.216SC..SBendtrans-59.8128.6174.2-24.735.7000111.6V386 Y388P365-V386 CarbonylContact C-O 3.49Å; P365-V386 WeakPolarHBondContact CA-O 3.4Å; P365-Y388 HydrophobicContact CG-CD2 3.96Å; P365-Y388 HydrophobicContact CG-CG 4.35Å
366G98.4Very high97.5Very high27 Ų2736.9 Ų36.928%0.27822%0.215SC..EExtended strand (participates in β ladder)trans166.2178-174.600000113.8L364 Y368 V386L364-G366 PolarHBondContact O-N 3.05Å; G366-Y368 WeakPolarHBondContact O-CD2 3.33Å; G366-V386 PolarHBondContact N-O 2.86Å; G366-V386 WeakPolarHBondContact O-CB 3Å; G366-V386 PolarHBondContact O-N 3.37Å
367N98.5Very high97.4Very high120 Ų12035 Ų3564%0.64221%0.206SC*.EExtended strand (participates in β ladder)trans-99.8126.6176.4-66.6-28.3000110.1L384 S385N367-L384 WeakPolarHBondContact CA-O 2.94Å; N367-S385 WeakPolarHBondContact OD1-CA 3.02Å; N367-S385 WeakPolarHBondContact OD1-CB 3.43Å; N367-S385 PolarHBondContact OD1-OG 3.47Å
368Y98.6Very high97.1Very high33 Ų3339.2 Ų39.213%0.12923%0.226CC..EExtended strand (participates in β ladder)trans-131.4135.7-174.9-62.9-87.4000111V342 L363 L364 G366 T383 L384 V386V342-Y368 HydrophobicContact CG1-CD1 3.65Å; V342-Y368 HydrophobicContact CG1-CG 4.25Å; L363-Y368 HydrophobicContact CB-CD2 4.5Å; L363-Y368 HydrophobicContact CB-CE2 3.98Å; L363-Y368 HydrophobicContact CD1-CD1 4.17Å; L363-Y368 HydrophobicContact CD1-CD2 3.94Å; L363-Y368 HydrophobicContact CD1-CE1 4.46Å; L363-Y368 HydrophobicContact CD1-CE2 4.24Å; L363-Y368 HydrophobicContact CD1-CG 3.88Å; L363-Y368 HydrophobicContact CD2-CD1 4.19Å; L363-Y368 HydrophobicContact CD2-CE1 3.92Å; L364-Y368 VanDerWaalsContact O-CE2 3.23Å; L364-Y368 WeakPolarHBondContact O-CE2 3.47Å; L364-Y368 PolarHBondContact O-OH 2.94Å; L364-Y368 VanDerWaalsContact O-OH 3.09Å; G366-Y368 WeakPolarHBondContact O-CD2 3.33Å; Y368-T383 CarbonylContact O-C 3.55Å; Y368-T383 VanDerWaalsContact O-CA 3.3Å; Y368-T383 WeakPolarHBondContact O-CA 3.44Å; Y368-L384 PolarHBondContact N-O 2.72Å; Y368-L384 PolarHBondContact O-N 3.4Å; Y368-V386 HydrophobicContact CD2-CB 4.06Å; Y368-V386 HydrophobicContact CD2-CG2 3.58Å; Y368-V386 HydrophobicContact CE2-CB 4.12Å; Y368-V386 HydrophobicContact CE2-CG2 4.11Å
369T98.6Very high97Very high33 Ų3343.5 Ų43.520%0.20225%0.252CS..EExtended strand (participates in β ladder)trans-94116.2171.7-61.50000109.4E343 T381 T383E343-T369 PolarHBondContact N-O 2.94Å; T369-T381 HydrophobicContact CG2-CG2 3.43Å; T369-T381 VanDerWaalsContact CG2-CG2 3.43Å; T369-T383 PolarHBondContact OG1-OG1 3.2Å
370F98.5Very high97Very high0 Ų045.4 Ų45.40%026%0.263CS..EExtended strand (participates in β ladder)trans-89.3139.4175-74.8-101.5000110.3V323 V340 E341 V342 Y359 R361 L363 T381 E382 L384 F400V323-F370 HydrophobicContact CB-CZ 4.03Å; V323-F370 HydrophobicContact CG2-CE2 4.17Å; V323-F370 HydrophobicContact CG2-CZ 3.8Å; V340-F370 HydrophobicContact CG1-CD1 3.96Å; V340-F370 HydrophobicContact CG1-CE1 4.36Å; E341-F370 CarbonylContact O-C 3.38Å; E341-F370 VanDerWaalsContact O-CA 3.29Å; E341-F370 WeakPolarHBondContact O-CA 3.36Å; V342-F370 HydrophobicContact CG2-CD1 3.97Å; V342-F370 HydrophobicContact CG2-CE1 3.63Å; V342-F370 HydrophobicContact CG2-CE2 4.47Å; V342-F370 HydrophobicContact CG2-CZ 3.91Å; Y359-F370 HydrophobicContact CE2-CE1 4.45Å; R361-F370 HydrophobicContact CB-CE1 4.27Å; R361-F370 HydrophobicContact CG-CE1 4.18Å; L363-F370 HydrophobicContact CD1-CE2 4.24Å; L363-F370 HydrophobicContact CD1-CZ 3.65Å; F370-T381 VanDerWaalsContact O-CA 3.27Å; F370-T381 WeakPolarHBondContact O-CA 3.45Å; F370-E382 PolarHBondContact N-O 3.05Å; F370-E382 PolarHBondContact O-N 2.69Å; F370-L384 HydrophobicContact CD2-CB 4.34Å; F370-L384 HydrophobicContact CD2-CD1 3.77Å; F370-L384 HydrophobicContact CD2-CG 3.98Å; F370-L384 HydrophobicContact CE2-CB 4.19Å; F370-L384 HydrophobicContact CE2-CD1 3.73Å; F370-L384 HydrophobicContact CE2-CG 4.17Å; F370-L384 HydrophobicContact CZ-CD1 4.42Å; F370-F400 HydrophobicContact CB-CE1 4.2Å; F370-F400 HydrophobicContact CB-CZ 3.66Å; F370-F400 HydrophobicContact CD1-CE2 4.19Å; F370-F400 AromaticContact CD1-CZ 3.9Å; F370-F400 HydrophobicContact CD1-CZ 3.9Å; F370-F400 HydrophobicContact CD2-CZ 4.43Å; F370-F400 HydrophobicContact CG-CE2 4.48Å; F370-F400 AromaticContact CG-CZ 3.74Å; F370-F400 HydrophobicContact CG-CZ 3.74Å
371K97.9Very high96.9Very high76 Ų7648.4 Ų48.433%0.3328%0.283SS..EExtended strand (participates in β ladder)trans-117.9116.6168.5-68.4-178-174.9170.10108.4E341 E343 L380 T381E341-K371 PolarHBondContact N-O 2.71Å; E341-K371 PolarHBondContact O-N 3.39Å; E343-K371 IonicContact OE1-NZ 3.2Å; E343-K371 PolarHBondContact OE1-NZ 3.34Å; K371-L380 CarbonylContact C-O 3.56Å; K371-L380 WeakPolarHBondContact CA-O 3.45Å; K371-T381 HydrophobicContact CG-CG2 4.28Å
372V98.1Very high96.9Very high0 Ų051.5 Ų51.50%030%0.298CS..EExtended strand (participates in β ladder)trans-112.4124.9-179.8-170.60000109.4V327 V339 V340 V379 L380 F400 L402V327-V372 HydrophobicContact CG1-CG1 4.08Å; V327-V372 HydrophobicContact CG2-CG1 4.05Å; V339-V372 CarbonylContact O-C 3.54Å; V339-V372 VanDerWaalsContact O-CA 3.25Å; V339-V372 WeakPolarHBondContact O-CA 3.19Å; V340-V372 HydrophobicContact CG1-CG2 4.34Å; V340-V372 HydrophobicContact CG2-CG1 4.18Å; V372-V379 WeakPolarHBondContact O-CA 3.42Å; V372-L380 HydrophobicContact CB-CB 4.23Å; V372-L380 HydrophobicContact CG2-CD2 4.43Å; V372-L380 PolarHBondContact N-O 3.02Å; V372-L380 PolarHBondContact O-N 2.03Å; V372-F400 HydrophobicContact CG2-CB 4.29Å; V372-F400 HydrophobicContact CG2-CD1 4.05Å; V372-F400 HydrophobicContact CG2-CD2 3.58Å; V372-F400 HydrophobicContact CG2-CE1 4.2Å; V372-F400 HydrophobicContact CG2-CE2 3.73Å; V372-F400 HydrophobicContact CG2-CG 3.72Å; V372-F400 HydrophobicContact CG2-CZ 4.05Å; V372-L402 HydrophobicContact CB-CD2 4.34Å; V372-L402 HydrophobicContact CG1-CD2 3.99Å
373S96.5Very high96.9Very high31 Ų3155.5 Ų55.522%0.21732%0.322CS..EExtended strand (participates in β ladder)trans-134.6145.1-178.1690000112.3V339V339-S373 PolarHBondContact N-O 2.96Å; V339-S373 PolarHBondContact O-N 3.4Å
374Y95.7Very high96.9Very high82 Ų8256 Ų5632%0.32233%0.325SS..  trans-153.5141.2175.5-175.6-111.8000109V335 Q336 A338 G376 H377 L402V335-Y374 HydrophobicContact CG1-CD1 3.61Å; V335-Y374 HydrophobicContact CG1-CD2 3.57Å; V335-Y374 HydrophobicContact CG1-CE1 3.69Å; V335-Y374 HydrophobicContact CG1-CE2 3.62Å; V335-Y374 HydrophobicContact CG1-CG 3.58Å; Q336-Y374 WeakPolarHBondContact O-CE2 3.33Å; A338-Y374 HydrophobicContact CB-CD2 4.21Å; A338-Y374 HydrophobicContact CB-CG 4.47Å; Y374-G376 PolarHBondContact O-N 3.02Å; Y374-H377 AromaticContact CD1-CE1 3.64Å; Y374-H377 AromaticContact CD1-ND1 3.41Å; Y374-H377 WeakPolarHBondContact CD1-ND1 3.29Å; Y374-H377 AromaticContact CE1-CE1 3.97Å; Y374-H377 WeakPolarHBondContact O-CB 2.98Å; Y374-H377 PolarHBondContact O-N 2.86Å; Y374-H377 VanDerWaalsContact O-N 3.1Å; Y374-L402 HydrophobicContact CG-CD1 4.36Å
375P93.1Very high96.9Very high105 Ų10558.3 Ų58.368%0.68234%0.344SS*.THydrogen-bonded Turntrans-51.7136.5-177.7-29.837000113.6H377P375-H377 VanDerWaalsContact C-N 3.25Å; P375-H377 PolarHBondContact O-N 3.5Å; P375-H377 PolarHBondContact O-ND1 3Å
376G90.3Very high96.9Very high59 Ų5955 Ų5561%0.60832%0.323SS*.THydrogen-bonded Turntrans74.67.3-17900000115.4Y374 V405Y374-G376 PolarHBondContact O-N 3.02Å; G376-V405 PolarHBondContact O-N 3.45Å
377H93.3Very high96.9Very high26 Ų2656.7 Ų56.712%0.1233%0.329CS..BIsolated β-bridgetrans-120.2154.3178.1-62.569.1000111.4Y374 P375 L402 R403Y374-H377 AromaticContact CD1-CE1 3.64Å; Y374-H377 AromaticContact CD1-ND1 3.41Å; Y374-H377 WeakPolarHBondContact CD1-ND1 3.29Å; Y374-H377 AromaticContact CE1-CE1 3.97Å; Y374-H377 WeakPolarHBondContact O-CB 2.98Å; Y374-H377 PolarHBondContact O-N 2.86Å; Y374-H377 VanDerWaalsContact O-N 3.1Å; P375-H377 VanDerWaalsContact C-N 3.25Å; P375-H377 PolarHBondContact O-N 3.5Å; P375-H377 PolarHBondContact O-ND1 3Å; H377-L402 HydrophobicContact CB-CB 4.16Å; H377-L402 HydrophobicContact CB-CD1 4.34Å; H377-R403 CarbonylContact C-O 3.58Å; H377-R403 VanDerWaalsContact CA-O 3.28Å; H377-R403 WeakPolarHBondContact CA-O 3.28Å; H377-R403 WeakPolarHBondContact CB-O 3.46Å
378E93.9Very high96.8Very high89 Ų8954.6 Ų54.642%0.41631%0.312SS..PPolyproline II helixtrans-65.1142.7170.1-64.3176.5174.900109.5L380 R403 V405E378-L380 PolarHBondContact O-N 2.95Å; E378-R403 PolarHBondContact N-O 3.07Å; E378-V405 HydrophobicContact CG-CG2 4.16Å
379V95.9Very high96.8Very high92 Ų9253.1 Ų53.156%0.55831%0.307SS*.PPolyproline II helixtrans-71.6117.7173.3179.40000108.4V372V372-V379 WeakPolarHBondContact O-CA 3.42Å
380L96.8Very high96.8Very high46 Ų4651.7 Ų51.724%0.24130%0.298CS..EExtended strand (participates in β ladder)trans-82.8131.7174.8-174.487.9000108.7K371 V372 E378 F400 L402K371-L380 CarbonylContact C-O 3.56Å; K371-L380 WeakPolarHBondContact CA-O 3.45Å; V372-L380 HydrophobicContact CB-CB 4.23Å; V372-L380 HydrophobicContact CG2-CD2 4.43Å; V372-L380 PolarHBondContact N-O 3.02Å; V372-L380 PolarHBondContact O-N 2.03Å; E378-L380 PolarHBondContact O-N 2.95Å; L380-F400 HydrophobicContact CD2-CB 3.84Å; L380-F400 HydrophobicContact CD2-CD1 3.35Å; L380-F400 HydrophobicContact CD2-CE1 4.19Å; L380-F400 HydrophobicContact CD2-CG 3.93Å; L380-L402 HydrophobicContact CB-CD2 4.11Å
381T97.8Very high96.6Very high81 Ų8159.1 Ų59.150%0.49733%0.333SS..EExtended strand (participates in β ladder)trans-123.5125.2170.6-57.30000109.2T369 F370 K371T369-T381 HydrophobicContact CG2-CG2 3.43Å; T369-T381 VanDerWaalsContact CG2-CG2 3.43Å; F370-T381 VanDerWaalsContact O-CA 3.27Å; F370-T381 WeakPolarHBondContact O-CA 3.45Å; K371-T381 HydrophobicContact CG-CG2 4.28Å
382E98.3Very high96.6Very high69 Ų6962.4 Ų62.432%0.32235%0.35SS..EExtended strand (participates in β ladder)trans-145137.6-177.1-172.7175.5179.300110.6F370 L384 H398 F400F370-E382 PolarHBondContact N-O 3.05Å; F370-E382 PolarHBondContact O-N 2.69Å; E382-L384 HydrophobicContact CG-CD2 4.04Å; E382-H398 IonicContact OE1-CE1 2.74Å; E382-H398 PolarHBondContact OE1-CE1 3.46Å; E382-H398 IonicContact OE1-NE2 3.66Å; E382-H398 PolarHBondContact OE1-NE2 3.37Å; E382-H398 IonicContact OE2-CE1 3.42Å; E382-H398 IonicContact OE2-NE2 2.85Å; E382-H398 PolarHBondContact OE2-NE2 3.39Å; E382-F400 HydrophobicContact CB-CE1 4.24Å; E382-F400 WeakPolarHBondContact OE2-CE1 3.18Å
383T98.5Very high96.5Very high90 Ų9063.9 Ų63.955%0.55236%0.355SS*.EExtended strand (participates in β ladder)trans-99.8125.9177.1-56.30000110.3Y368 T369Y368-T383 CarbonylContact O-C 3.55Å; Y368-T383 VanDerWaalsContact O-CA 3.3Å; Y368-T383 WeakPolarHBondContact O-CA 3.44Å; T369-T383 PolarHBondContact OG1-OG1 3.2Å
384L98.6Very high96.6Very high9 Ų963.8 Ų63.85%0.04735%0.354CS..EExtended strand (participates in β ladder)trans-115.3142.7179.7-55.2-178.8000110.6V323 N367 Y368 F370 E382 M396 H398 F400V323-L384 HydrophobicContact CG1-CD1 4.06Å; V323-L384 HydrophobicContact CG2-CD1 4.4Å; N367-L384 WeakPolarHBondContact CA-O 2.94Å; Y368-L384 PolarHBondContact N-O 2.72Å; Y368-L384 PolarHBondContact O-N 3.4Å; F370-L384 HydrophobicContact CD2-CB 4.34Å; F370-L384 HydrophobicContact CD2-CD1 3.77Å; F370-L384 HydrophobicContact CD2-CG 3.98Å; F370-L384 HydrophobicContact CE2-CB 4.19Å; F370-L384 HydrophobicContact CE2-CD1 3.73Å; F370-L384 HydrophobicContact CE2-CG 4.17Å; F370-L384 HydrophobicContact CZ-CD1 4.42Å; E382-L384 HydrophobicContact CG-CD2 4.04Å; L384-M396 HydrophobicContact CB-CE 4.4Å; L384-M396 HydrophobicContact CD2-CE 4.41Å; L384-H398 HydrophobicContact CD1-CB 4Å; L384-F400 HydrophobicContact CD1-CZ 4.16Å
385S98.5Very high96.8Very high84 Ų8460.1 Ų60.159%0.58734%0.341SS*.EExtended strand (participates in β ladder)trans-98107.8170.1-162.80000109.1N367 M396N367-S385 WeakPolarHBondContact OD1-CA 3.02Å; N367-S385 WeakPolarHBondContact OD1-CB 3.43Å; N367-S385 PolarHBondContact OD1-OG 3.47Å; S385-M396 VanDerWaalsContact O-SD 3.39Å
386V98.6Very high97Very high4 Ų457.6 Ų57.62%0.02432%0.321CS..EExtended strand (participates in β ladder)trans-90.2120.8-171.51790000109.6V323 L363 P365 G366 Y368V323-V386 HydrophobicContact CG2-CB 4.48Å; V323-V386 HydrophobicContact CG2-CG1 4.28Å; V323-V386 HydrophobicContact CG2-CG2 3.43Å; V323-V386 VanDerWaalsContact CG2-CG2 3.43Å; L363-V386 HydrophobicContact CB-CG1 4.44Å; L363-V386 HydrophobicContact CD1-CG2 4.41Å; P365-V386 CarbonylContact C-O 3.49Å; P365-V386 WeakPolarHBondContact CA-O 3.4Å; G366-V386 PolarHBondContact N-O 2.86Å; G366-V386 WeakPolarHBondContact O-CB 3Å; G366-V386 PolarHBondContact O-N 3.37Å; Y368-V386 HydrophobicContact CD2-CB 4.06Å; Y368-V386 HydrophobicContact CD2-CG2 3.58Å; Y368-V386 HydrophobicContact CE2-CB 4.12Å; Y368-V386 HydrophobicContact CE2-CG2 4.11Å
387P98.3Very high97.4Very high62 Ų6262 Ų6240%0.40332%0.323SS..  trans-85.3173.6174.836.3-35.3000112.2G389 M396P387-G389 PolarHBondContact O-N 2.94Å; P387-M396 HydrophobicContact CG-CB 4.3Å
388Y98.2Very high97.7Very high75 Ų7562.5 Ų62.529%0.29433%0.325SS..  trans-77.7108.2168.8-169-113.1000110.6Q318 L321 P365 P390 E391Q318-Y388 PolarHBondContact NE2-OH 3.01Å; L321-Y388 HydrophobicContact CD2-CD2 3.89Å; L321-Y388 HydrophobicContact CD2-CE2 3.75Å; P365-Y388 HydrophobicContact CG-CD2 3.96Å; P365-Y388 HydrophobicContact CG-CG 4.35Å; Y388-P390 HydrophobicContact CD2-CG 4.43Å; Y388-P390 HydrophobicContact CE1-CB 4.1Å; Y388-P390 HydrophobicContact CE1-CG 4.28Å; Y388-P390 HydrophobicContact CE2-CG 3.86Å; Y388-E391 HydrophobicContact CD1-CG 4.19Å; Y388-E391 HydrophobicContact CE1-CG 3.9Å
389G97.7Very high97.9Very high2 Ų262.3 Ų62.32%0.02133%0.328CS..  trans-87.1-29.2-175.900000118.2H320 P387 E391 Q392 Y393 S394H320-G389 CarbonylContact O-C 3.33Å; H320-G389 WeakPolarHBondContact O-CA 3.33Å; P387-G389 PolarHBondContact O-N 2.94Å; G389-E391 VanDerWaalsContact C-N 3.33Å; G389-E391 PolarHBondContact O-N 2.86Å; G389-Q392 PolarHBondContact O-N 3.03Å; G389-Y393 PolarHBondContact O-N 2.94Å; G389-S394 VanDerWaalsContact CA-O 3.26Å; G389-S394 WeakPolarHBondContact CA-O 3.36Å; G389-S394 PolarHBondContact O-N 2.92Å
390P98Very high98Very high3 Ų358 Ų582%0.01930%0.301CS..G310 helixtrans-52.9-39.9-174.5-33.438.6000116.1L321 Y388 Q392 Y393L321-P390 HydrophobicContact CD2-CG 3.67Å; L321-P390 HydrophobicContact CG-CG 3.73Å; Y388-P390 HydrophobicContact CD2-CG 4.43Å; Y388-P390 HydrophobicContact CE1-CB 4.1Å; Y388-P390 HydrophobicContact CE1-CG 4.28Å; Y388-P390 HydrophobicContact CE2-CG 3.86Å; P390-Q392 PolarHBondContact O-N 3.35Å; P390-Y393 PolarHBondContact O-N 2.97Å; P390-Y393 VanDerWaalsContact O-N 3.16Å
391E95.6Very high98.1Very high156 Ų15661.6 Ų61.673%0.72932%0.315SS*.G310 helixtrans-65.7-24.7177.9-75.4174-171.200113.7Y388 G389Y388-E391 HydrophobicContact CD1-CG 4.19Å; Y388-E391 HydrophobicContact CE1-CG 3.9Å; G389-E391 VanDerWaalsContact C-N 3.33Å; G389-E391 PolarHBondContact O-N 2.86Å
392Q96.2Very high98Very high146 Ų14657.8 Ų57.868%0.68229%0.292SS*.G310 helixtrans-97.62.7179.7-60.7177.534.200112.3G389 P390 S394G389-Q392 PolarHBondContact O-N 3.03Å; P390-Q392 PolarHBondContact O-N 3.35Å; Q392-S394 PolarHBondContact O-N 2.67Å; Q392-S394 VanDerWaalsContact O-N 3.13Å
393Y97.8Very high97.7Very high31 Ų3162.9 Ų62.912%0.12231%0.308CS..THydrogen-bonded Turntrans53.730.7-175.5-63.7-97.6000113.1Q114 L115 S118 Q317 H320 G389 P390Q114-Y393 HydrophobicContact CB-CD1 4Å; Q114-Y393 HydrophobicContact CB-CD2 3.92Å; Q114-Y393 HydrophobicContact CB-CE1 3.83Å; Q114-Y393 HydrophobicContact CB-CE2 3.76Å; Q114-Y393 HydrophobicContact CB-CG 4.03Å; Q114-Y393 HydrophobicContact CG-CD2 4.41Å; Q114-Y393 HydrophobicContact CG-CE2 4.26Å; L115-Y393 HydrophobicContact CB-CD1 4.48Å; L115-Y393 HydrophobicContact CB-CE1 4.02Å; L115-Y393 HydrophobicContact CD1-CD1 4.13Å; L115-Y393 HydrophobicContact CD1-CE1 3.91Å; S118-Y393 VanDerWaalsContact CB-O 3.25Å; S118-Y393 WeakPolarHBondContact CB-O 3.1Å; Q317-Y393 HydrophobicContact CG-CE1 4.12Å; Q317-Y393 PolarHBondContact NE2-OH 3.38Å; H320-Y393 VanDerWaalsContact CD2-C 3.46Å; H320-Y393 WeakPolarHBondContact CD2-CA 3.45Å; H320-Y393 PolarHBondContact CE1-O 3.15Å; H320-Y393 VanDerWaalsContact CG-C 3.41Å; H320-Y393 PolarHBondContact ND1-O 2.89Å; G389-Y393 PolarHBondContact O-N 2.94Å; P390-Y393 PolarHBondContact O-N 2.97Å; P390-Y393 VanDerWaalsContact O-N 3.16Å
394S98.3Very high97.3Very high28 Ų2866.4 Ų66.420%0.19631%0.311CS..SBendtrans-158.6131.8175.6-173.10000111.9H320 K324 G389 Q392H320-S394 CarbonylContact O-C 3.59Å; K324-S394 VanDerWaalsContact CE-OG 3.22Å; K324-S394 WeakPolarHBondContact CE-OG 2.87Å; K324-S394 PolarHBondContact NZ-OG 3.28Å; G389-S394 VanDerWaalsContact CA-O 3.26Å; G389-S394 WeakPolarHBondContact CA-O 3.36Å; G389-S394 PolarHBondContact O-N 2.92Å; Q392-S394 PolarHBondContact O-N 2.67Å; Q392-S394 VanDerWaalsContact O-N 3.13Å
395A98.5Very high96.6Very high5 Ų570 Ų704%0.04133%0.333CS..PPolyproline II helixtrans-61.1158.2160.300000110.8H320 L321 G322 K324 K397H320-A395 WeakPolarHBondContact O-CA 3.32Å; H320-A395 PolarHBondContact O-N 3.1Å; H320-A395 VanDerWaalsContact O-N 3.11Å; L321-A395 WeakPolarHBondContact O-CB 3.36Å; G322-A395 WeakPolarHBondContact O-CB 3.48Å; K324-A395 HydrophobicContact CB-CB 4.28Å; K324-A395 HydrophobicContact CD-CB 4.04Å; K324-A395 HydrophobicContact CG-CB 3.91Å; A395-K397 PolarHBondContact O-N 3.49Å
396M98.6Very high95.6Very high52 Ų5269.7 Ų69.726%0.25634%0.336SS..EExtended strand (participates in β ladder)trans-57.4126.7172.5176.2-177.2176.200109.3G322 V323 K324 L384 S385 P387G322-M396 PolarHBondContact O-N 3.13Å; V323-M396 CarbonylContact C-O 3.55Å; V323-M396 WeakPolarHBondContact CA-O 3.46Å; V323-M396 WeakPolarHBondContact CG1-O 3.44Å; V323-M396 HydrophobicContact CG2-CB 4.4Å; V323-M396 HydrophobicContact CG2-SD 4.44Å; K324-M396 PolarHBondContact N-O 3.08Å; L384-M396 HydrophobicContact CB-CE 4.4Å; L384-M396 HydrophobicContact CD2-CE 4.41Å; S385-M396 VanDerWaalsContact O-SD 3.39Å; P387-M396 HydrophobicContact CG-CB 4.3Å
397K98.7Very high93.7Very high153 Ų15376 Ų7667%0.66538%0.38SS*.EExtended strand (participates in β ladder)trans-88.2121.3178-64.8-179.3-176.5175.90109.4K324 A395K324-K397 HydrophobicContact CG-CG 4.35Å; K324-K397 CarbonylContact O-C 3.59Å; K324-K397 VanDerWaalsContact O-CA 3.26Å; K324-K397 WeakPolarHBondContact O-CA 3.38Å; A395-K397 PolarHBondContact O-N 3.49Å
398H98.6Very high91.2Very high35 Ų3576.4 Ų76.416%0.16239%0.389CS..  trans-143.1133.2175.6-170.273.2000110.4V323 K324 G325 Y359 E382 L384 F400V323-H398 HydrophobicContact CG1-CB 3.84Å; K324-H398 PolarHBondContact O-N 3.35Å; G325-H398 VanDerWaalsContact CA-O 3.32Å; G325-H398 WeakPolarHBondContact CA-O 3.24Å; Y359-H398 WeakPolarHBondContact CE1-O 3.22Å; Y359-H398 PolarHBondContact OH-O 2.86Å; E382-H398 IonicContact OE1-CE1 2.74Å; E382-H398 PolarHBondContact OE1-CE1 3.46Å; E382-H398 IonicContact OE1-NE2 3.66Å; E382-H398 PolarHBondContact OE1-NE2 3.37Å; E382-H398 IonicContact OE2-CE1 3.42Å; E382-H398 IonicContact OE2-NE2 2.85Å; E382-H398 PolarHBondContact OE2-NE2 3.39Å; L384-H398 HydrophobicContact CD1-CB 4Å; H398-F400 AromaticContact CD2-CD1 3.64Å; H398-F400 AromaticContact CD2-CE1 3.32Å; H398-F400 WeakPolarHBondContact CD2-CE1 3.49Å; H398-F400 AromaticContact CD2-CZ 3.65Å; H398-F400 AromaticContact NE2-CD1 3.63Å; H398-F400 AromaticContact NE2-CE1 3.46Å; H398-F400 WeakPolarHBondContact NE2-CE1 3.37Å
399N98.5Very high88.7Confident86 Ų8680.3 Ų80.346%0.4642%0.42SS..  trans-111135.5177.8-68.7-24.9000109.3Q326 F328Q326-N399 PolarHBondContact N-OD1 3.06Å; Q326-N399 CarbonylContact O-C 3.34Å; Q326-N399 WeakPolarHBondContact O-CA 3.39Å; Q326-N399 WeakPolarHBondContact O-CB 3.36Å; F328-N399 HydrophobicContact CD2-CB 4.2Å; F328-N399 HydrophobicContact CE2-CB 3.94Å
400F98.5Very high86Confident1 Ų185.2 Ų85.20%0.00445%0.45CS..EExtended strand (participates in β ladder)trans-98.1143.3174.9-63.5-65.2000110.3Q326 V327 F328 V340 Y359 F370 V372 L380 E382 L384 H398Q326-F400 PolarHBondContact O-N 2.98Å; V327-F400 CarbonylContact C-O 3.54Å; V327-F400 WeakPolarHBondContact CA-O 3.46Å; V327-F400 HydrophobicContact CG1-CB 4.46Å; V327-F400 HydrophobicContact CG2-CB 4.23Å; V327-F400 HydrophobicContact CG2-CD2 4.25Å; F328-F400 PolarHBondContact N-O 3.12Å; V340-F400 HydrophobicContact CG1-CE2 4.03Å; Y359-F400 HydrophobicContact CD1-CD2 4.35Å; Y359-F400 AromaticContact CE1-CD2 3.56Å; Y359-F400 HydrophobicContact CE1-CD2 3.56Å; Y359-F400 AromaticContact CE1-CE2 3.71Å; Y359-F400 HydrophobicContact CE1-CE2 3.71Å; Y359-F400 AromaticContact CE2-CE2 3.91Å; Y359-F400 HydrophobicContact CE2-CE2 3.91Å; Y359-F400 AromaticContact CZ-CD2 3.69Å; Y359-F400 AromaticContact CZ-CE2 3.3Å; Y359-F400 WeakPolarHBondContact OH-CE2 3.08Å; F370-F400 HydrophobicContact CB-CE1 4.2Å; F370-F400 HydrophobicContact CB-CZ 3.66Å; F370-F400 HydrophobicContact CD1-CE2 4.19Å; F370-F400 AromaticContact CD1-CZ 3.9Å; F370-F400 HydrophobicContact CD1-CZ 3.9Å; F370-F400 HydrophobicContact CD2-CZ 4.43Å; F370-F400 HydrophobicContact CG-CE2 4.48Å; F370-F400 AromaticContact CG-CZ 3.74Å; F370-F400 HydrophobicContact CG-CZ 3.74Å; V372-F400 HydrophobicContact CG2-CB 4.29Å; V372-F400 HydrophobicContact CG2-CD1 4.05Å; V372-F400 HydrophobicContact CG2-CD2 3.58Å; V372-F400 HydrophobicContact CG2-CE1 4.2Å; V372-F400 HydrophobicContact CG2-CE2 3.73Å; V372-F400 HydrophobicContact CG2-CG 3.72Å; V372-F400 HydrophobicContact CG2-CZ 4.05Å; L380-F400 HydrophobicContact CD2-CB 3.84Å; L380-F400 HydrophobicContact CD2-CD1 3.35Å; L380-F400 HydrophobicContact CD2-CE1 4.19Å; L380-F400 HydrophobicContact CD2-CG 3.93Å; E382-F400 HydrophobicContact CB-CE1 4.24Å; E382-F400 WeakPolarHBondContact OE2-CE1 3.18Å; L384-F400 HydrophobicContact CD1-CZ 4.16Å; H398-F400 AromaticContact CD2-CD1 3.64Å; H398-F400 AromaticContact CD2-CE1 3.32Å; H398-F400 WeakPolarHBondContact CD2-CE1 3.49Å; H398-F400 AromaticContact CD2-CZ 3.65Å; H398-F400 AromaticContact NE2-CD1 3.63Å; H398-F400 AromaticContact NE2-CE1 3.46Å; H398-F400 WeakPolarHBondContact NE2-CE1 3.37Å
401K97.5Very high83.3Confident122 Ų12297.1 Ų97.153%0.5349%0.494SS..EExtended strand (participates in β ladder)trans-123.3114.2175.4-170.2174.5-177.9175.20110.5F328 D329 G330F328-K401 CarbonylContact O-C 3.49Å; F328-K401 WeakPolarHBondContact O-CA 3.1Å; D329-K401 VanDerWaalsContact O-CE 3.3Å; D329-K401 WeakPolarHBondContact O-CE 3.12Å; G330-K401 WeakPolarHBondContact O-CE 3.36Å; G330-K401 PolarHBondContact O-NZ 3.07Å
402L95.9Very high80.7Confident1 Ų195.1 Ų95.11%0.00549%0.492CS..  trans-81.6145.3-179.2-65178.2000111.7V327 F328 G330 V372 Y374 H377 L380V327-L402 HydrophobicContact CG1-CD1 3.74Å; V327-L402 HydrophobicContact CG1-CG 3.82Å; F328-L402 PolarHBondContact O-N 3.09Å; G330-L402 PolarHBondContact N-O 2.9Å; V372-L402 HydrophobicContact CB-CD2 4.34Å; V372-L402 HydrophobicContact CG1-CD2 3.99Å; Y374-L402 HydrophobicContact CG-CD1 4.36Å; H377-L402 HydrophobicContact CB-CB 4.16Å; H377-L402 HydrophobicContact CB-CD1 4.34Å; L380-L402 HydrophobicContact CB-CD2 4.11Å
403R93.4Very high77.8Confident176 Ų17696.9 Ų96.966%0.66450%0.501SS*.  trans-106.9136.5173.4-60.1-17977.9173.61.7109.1H377 E378H377-R403 CarbonylContact C-O 3.58Å; H377-R403 VanDerWaalsContact CA-O 3.28Å; H377-R403 WeakPolarHBondContact CA-O 3.28Å; H377-R403 WeakPolarHBondContact CB-O 3.46Å; E378-R403 PolarHBondContact N-O 3.07Å
404R88.8Confident74.9Confident163 Ų16399.5 Ų99.562%0.61553%0.529SS*.BIsolated β-bridgetrans-69.1142.6173.3-77.5-169.7177.9-165.80.8109.9A406R404-A406 PolarHBondContact O-N 3.41Å
405V85.4Confident71.9Confident84 Ų84106.4 Ų106.451%0.50956%0.558SS.*PPolyproline II helixtrans-63.1125.7170.9-174.50000108.2G376 E378 S407G376-V405 PolarHBondContact O-N 3.45Å; E378-V405 HydrophobicContact CG-CG2 4.16Å; V405-S407 PolarHBondContact O-N 3.27Å
406A75.7Confident69.1Low79 Ų79111.9 Ų111.965%0.65359%0.593SS**PPolyproline II helixtrans-60.3133.3173.100000109R404 A408R404-A406 PolarHBondContact O-N 3.41Å; A406-A408 VanDerWaalsContact C-N 3.29Å; A406-A408 PolarHBondContact O-N 3Å
407S59.8Low66.3Low137 Ų137112.6 Ų112.696%0.95860%0.603SS**  trans-65.289.3-177.9-1600000110.3V405V405-S407 PolarHBondContact O-N 3.27Å
408A45.7Very low63.5Low70 Ų70108.1 Ų108.158%0.57959%0.59SS**  trans-114.3132.2159.600000106.4A406 V410A406-A408 VanDerWaalsContact C-N 3.29Å; A406-A408 PolarHBondContact O-N 3Å; A408-V410 PolarHBondContact O-N 3.22Å
409T44.8Very low61Low156 Ų156109.7 Ų109.796%0.95761%0.605SS**  trans-53.778.4175.938.20000112.4
410V42.2Very low59.2Low105 Ų105107.8 Ų107.864%0.63660%0.597SS**  trans-129.1105.6166-170.50000105.8A408 V412A408-V410 PolarHBondContact O-N 3.22Å; V410-V412 HydrophobicContact CB-CG2 4.13Å; V410-V412 HydrophobicContact CG1-CG2 3.5Å; V410-V412 PolarHBondContact O-N 3.45Å
411R41.1Very low56.9Low254 Ų254113 Ų11396%0.95863%0.625SS**  trans-66.380.3158.1-80.8-177.3174.7-177.9-1.5106.5Q413R411-Q413 PolarHBondContact O-N 2.91Å; R411-Q413 VanDerWaalsContact O-N 3.15Å
412V40.2Very low54.5Low113 Ų113111.6 Ų111.669%0.68562%0.617SS**  trans-68.4108.5159.9-176.60000103.9V410 A414V410-V412 HydrophobicContact CB-CG2 4.13Å; V410-V412 HydrophobicContact CG1-CG2 3.5Å; V410-V412 PolarHBondContact O-N 3.45Å; V412-A414 VanDerWaalsContact C-N 3.25Å; V412-A414 PolarHBondContact O-N 3.03Å
413Q35.7Very low51.4Low184 Ų184115.6 Ų115.686%0.8665%0.646SS**  trans-56104.6158.1-83.3177.6-35.800104.8R411 E415R411-Q413 PolarHBondContact O-N 2.91Å; R411-Q413 VanDerWaalsContact O-N 3.15Å; Q413-E415 PolarHBondContact O-N 2.88Å
414A36.4Very low48.7Very low86 Ų86113.1 Ų113.171%0.71165%0.645SS**  trans-54.1116.7164.400000104.9V412V412-A414 VanDerWaalsContact C-N 3.25Å; V412-A414 PolarHBondContact O-N 3.03Å
415E36.5Very low45.8Very low172 Ų172111.9 Ų111.980%0.80465%0.65SS**  trans-51.2129.5161.8-75.2-164.2162.600105.5Q413 S417Q413-E415 PolarHBondContact O-N 2.88Å; E415-S417 PolarHBondContact O-N 3.26Å
416P38.4Very low43.2Very low121 Ų121113.6 Ų113.679%0.78666%0.662SS**  trans-56.3109.1177.621.8-29.6000106.3
417S39.8Very low41Very low66 Ų66121.7 Ų121.746%0.46268%0.676SS.*  trans-50.1130.9164.4-51.60000105.2E415 S419E415-S417 PolarHBondContact O-N 3.26Å; S417-S419 PolarHBondContact O-N 3.42Å
418P41.6Very low39.5Very low60 Ų60119.3 Ų119.339%0.3967%0.673SS.*  trans-48.6108.1179-2531.8000107.8C420 L425P418-C420 PolarHBondContact O-N 3.13Å; P418-L425 HydrophobicContact CB-CD2 4.37Å
419S44.8Very low38.6Very low68 Ų68119.6 Ų119.648%0.47668%0.683SS.*  trans-73.9122.6174.755.60000104.3S417 N421S417-S419 PolarHBondContact O-N 3.42Å; S419-N421 PolarHBondContact O-N 2.94Å
420C60.7Low37.7Very low45 Ų45117 Ų11730%0.30468%0.677SS.*  trans-65.325.6158.5-62.10000111.8C349 P418 Y422C349-C420 WeakPolarHBondContact CA-SG 3.33Å; C349-C420 HydrophobicContact CB-CB 4.27Å; C349-C420 WeakPolarHBondContact CB-SG 3.26Å; C349-C420 WeakPolarHBondContact SG-CB 3.48Å; C349-C420 CovalentContact SG-SG 2.02Å; C349-C420 PolarHBondContact SG-SG 3.46Å; P418-C420 PolarHBondContact O-N 3.13Å; C420-Y422 PolarHBondContact O-N 3.39Å
421N49.9Very low37.1Very low110 Ų110116.8 Ų116.859%0.58869%0.687SS**SBendtrans-67.7131.4160-82.3-16.7000105.7S419 S423S419-N421 PolarHBondContact O-N 2.94Å; N421-S423 PolarHBondContact O-N 2.72Å
422Y48.3Very low36.6Very low93 Ų93110 Ų11037%0.36568%0.684SS.*SBendtrans-527.2178.3-62.6-92.1000115.5L170 E172 R187 C420L170-Y422 HydrophobicContact CB-CD1 3.69Å; L170-Y422 HydrophobicContact CB-CE1 4.43Å; L170-Y422 HydrophobicContact CD1-CD1 3.83Å; L170-Y422 HydrophobicContact CD1-CG 4.49Å; L170-Y422 HydrophobicContact CG-CD1 4.37Å; E172-Y422 PolarHBondContact OE1-OH 3.28Å; R187-Y422 PolarHBondContact NH2-OH 3.27Å; C420-Y422 PolarHBondContact O-N 3.39Å
423S30.5Very low35.9Very low86 Ų86108.2 Ų108.260%0.60169%0.689SS**SBendtrans-112.998.8-179-0.70000109.8N421N421-S423 PolarHBondContact O-N 2.72Å
424L36.3Very low35.5Very low124 Ų124104.4 Ų104.465%0.64968%0.683SS**  trans33.3110.6145.4-62.3164.5000117.4
425L28.1Very low35.1Very low137 Ų137104.6 Ų104.672%0.71769%0.685SS**  trans-63.3127.3150.5-73.5166.5000108.7P418 R427P418-L425 HydrophobicContact CB-CD2 4.37Å; L425-R427 PolarHBondContact O-N 2.95Å
426P30Very low34.6Very low119 Ų119107.8 Ų107.877%0.77369%0.689SS**  trans-68.3131.1168.7-9.824.3000109.3G428P426-G428 PolarHBondContact O-N 3.44Å
427R31.1Very low34.2Very low250 Ų250109.8 Ų109.894%0.94369%0.693SS**  trans-56.7108.8165.1-86.2-179.4171.1-178.5-2.4109.4L425 G429L425-R427 PolarHBondContact O-N 2.95Å; R427-G429 PolarHBondContact O-N 2.86Å; R427-G429 VanDerWaalsContact O-N 3.13Å
428G27.2Very low33.5Very low86 Ų86110.1 Ų110.189%0.88771%0.708SS**  trans-72.694.1162.300000109.8P426P426-G428 PolarHBondContact O-N 3.44Å
429G27.4Very low32.9Very low76 Ų76115.3 Ų115.378%0.78473%0.731SS**  trans-103.2110.9167.400000110R427R427-G429 PolarHBondContact O-N 2.86Å; R427-G429 VanDerWaalsContact O-N 3.13Å
430A25.9Very low32.2Very low102 Ų102118.6 Ų118.684%0.84375%0.749SS**  trans-141.874.8158.700000108.5
431A29.2Very low30.7Very low101 Ų101123.2 Ų123.284%0.83578%0.775SS**  trans-72.1132.6154.900000107.7G433A431-G433 PolarHBondContact O-N 3.19Å
432A30.5Very low29.5Very low110 Ų110120.9 Ų120.991%0.90978%0.776SS**  trans-52.1116.5179.800000111.8
433G26.2Very low28.5Very low76 Ų76126.1 Ų126.178%0.78480%0.802SS**  trans-96.9111168.800000109.9A431A431-G433 PolarHBondContact O-N 3.19Å
434S27.7Very low28.4Very low105 Ų105127.1 Ų127.173%0.73481%0.809SS**  trans-55.6133.217250.10000112.4W436S434-W436 PolarHBondContact O-N 3.5Å
435A27.3Very low28.1Very low90 Ų90128.8 Ų128.874%0.74482%0.817SS**  trans-60.9126.8176.300000112.7
436W26.8Very low28.2Very low239 Ų239128.7 Ų128.791%0.90582%0.822SS**  trans-128.9110.9157.9-83.966.5000108.1S434S434-W436 PolarHBondContact O-N 3.5Å
437N28.2Very low28.3Very low162 Ų162129 Ų12987%0.86682%0.822SS**  trans-69.6136.3176.3-83.1-22000110.4
438G26.4Very low28.3Very low74 Ų74123.2 Ų123.276%0.76381%0.814SS**  trans-68.4152.7173.600000113.1
439L28.3Very low28.6Very low169 Ų169126.4 Ų126.489%0.88581%0.81SS**  trans-138.7109.7156-105.6156.8000107.6
440T29.5Very low28.8Very low137 Ų137131.6 Ų131.684%0.8481%0.814SS**  trans-70.5129.4166.640.50000110.5
441V30.3Very low29.4Very low142 Ų142132.5 Ų132.586%0.86181%0.809SS**  trans-143.2126.9152-178.20000107.9
442G25.4Very low29.6Very low60 Ų60134.4 Ų134.462%0.61981%0.81SS**  trans-92-165-179.300000114.6
443F27Very low29.7Very low204 Ų204137 Ų13790%0.89581%0.805SS**  trans80.5102.7171.2-75.5-76.5000117.8
444S27.4Very low30.4Very low107 Ų107144.8 Ų144.875%0.74883%0.829SS**  149.713992-84.10000113.8
445L29.6Very low30.6Very low159 Ų159146.8 Ų146.883%0.83283%0.834SS**  trans-40.8132.8163.5-112.878.3000113.6
446V30.8Very low30.7Very low134 Ų134149.7 Ų149.781%0.81284%0.838SS**  trans-148.4113.8135.4178.80000109.5V448V446-V448 HydrophobicContact CG1-CG2 4.21Å
447T31.5Very low31Very low126 Ų126144.8 Ų144.877%0.77384%0.835SS**  trans-70.4131159.424.20000111
448V32.4Very low31.1Very low129 Ų129143.8 Ų143.878%0.78283%0.833SS**  trans-142.6120.8149.9176.70000109.4V446V446-V448 HydrophobicContact CG1-CG2 4.21Å
449L32.9Very low31.4Very low153 Ų153148.1 Ų148.180%0.80184%0.837SS**  trans-64.1140.3164-86.6121.4000110.8
450Q32.1Very low31.6Very low184 Ų184146.7 Ų146.786%0.8683%0.834SS**  -169.9117126.2-107.8161.9-13.600112.1
451T36.9Very low31.8Very low121 Ų121147.4 Ų147.474%0.74283%0.834SS**  trans-40.1144.8148.541.20000112.9
452V33.7Very low31.9Very low141 Ų141147.8 Ų147.886%0.85583%0.832SS**  -171.6138.2122151.80000108.5
453M33.8Very low32.4Very low164 Ų164155.2 Ų155.281%0.80885%0.849SS**  trans-59.9142.2174.2-64.4153.857.500112.2
454D40.9Very low32.9Very low240 Ų240150.7 Ų150.7100%1.28385%0.845SS**  -156.70117.8-89.8-22.2000109.3

Retrieved 454 of 454 residues in 338.3 ms (Link to these results)