A0A087X5U0_POEFO Loading...

Iron-sulfur cluster co-chaperone protein HscB

Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Required for incorporation of iron-sulfur clusters into SDHB, the iron-sulfur protein subunit of succinate dehydrogenase that is involved in complex II of the mitochondrial electron transport chain. Recruited to SDHB by interaction with SDHAF1 which first binds SDHB and then recruits the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20. Plays an essential role in hematopoiesis. Acts as a co-chaperone in iron-sulfur cluster assembly in the cytoplasm. Also mediates complex formation between components of the cytosolic iron-sulfur biogenesis pathway and the CIA targeting complex composed of CIAO1, DIPK1B/FAM69B and MMS19 by binding directly to the scaffold protein ISCU and to CIAO1. This facilitates iron-sulfur cluster insertion into a number of cytoplasmic and nuclear proteins including POLD1, ELP3, DPYD and PPAT.

AlphaFold DB , UniProt , Accession A0A087X5U0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 276 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	I	44.3	Very low	32.4	Very low	223 Å²	223	154.4 Å²	154.4	100%	1.144	83%	0.833	S	S	*	*				0	79.5	0	-56	173.2	0	0	0	105.9
2	A	34.4	Very low	32.1	Very low	90 Å²	90	154.1 Å²	154.1	74%	0.744	83%	0.829	S	S	*	*				54.8	107.5	116.7	0	0	0	0	0	112.5
3	A	36	Very low	31.9	Very low	93 Å²	93	155.6 Å²	155.6	77%	0.769	84%	0.836	S	S	*	*				63.6	133.6	54	0	0	0	0	0	114.9
4	N	32.7	Very low	31.6	Very low	138 Å²	138	160.9 Å²	160.9	74%	0.738	84%	0.838	S	S	*	*			trans	99.7	140.6	174.9	-73.7	-21.9	0	0	0	116.7
5	R	33.7	Very low	31.4	Very low	207 Å²	207	159.8 Å²	159.8	78%	0.781	84%	0.84	S	S	*	*			cis	-171.1	150.3	-5	-117.1	167.5	-165.5	-155.9	-1.6	108.3
6	M	31.9	Very low	31.1	Very low	168 Å²	168	156 Å²	156	83%	0.828	83%	0.831	S	S	*	*			trans	-56	157.4	158.5	-68.7	167.7	133.1	0	0	112.5
7	F	30.1	Very low	30.9	Very low	193 Å²	193	153.8 Å²	153.8	85%	0.846	83%	0.831	S	S	*	*				-171.6	137.8	117.1	-100.9	-72	0	0	0	113.1
8	H	28.8	Very low	30.8	Very low	164 Å²	164	151.1 Å²	151.1	76%	0.759	83%	0.826	S	S	*	*			trans	-54	156.7	166.2	-89.2	-98.9	0	0	0	114.4
9	T	29.9	Very low	30.6	Very low	141 Å²	141	152.9 Å²	152.9	87%	0.865	83%	0.833	S	S	*	*				-179.4	151.9	108.9	27.7	0	0	0	0	114.2
10	N	28.1	Very low	30.6	Very low	150 Å²	150	156.9 Å²	156.9	80%	0.802	84%	0.835	S	S	*	*			trans	-53.9	154.2	-178.6	-70.2	-42.8	0	0	0	116.1
11	C	26.3	Very low	30.5	Very low	131 Å²	131	154.1 Å²	154.1	89%	0.885	84%	0.835	S	S	*	*			trans	-148.1	119.6	135.2	-151.9	0	0	0	0	111.9
12	L	28.8	Very low	29.8	Very low	151 Å²	151	148.1 Å²	148.1	79%	0.791	82%	0.818	S	S	*	*			trans	-69	148.9	169.9	-66	156.6	0	0	0	109.7
13	L	29.6	Very low	29.5	Very low	174 Å²	174	155 Å²	155	91%	0.911	83%	0.825	S	S	*	*			trans	-159	121.3	137.7	-103.8	159.5	0	0	0	111.1
14	R	27.3	Very low	29	Very low	229 Å²	229	156.6 Å²	156.6	86%	0.864	83%	0.829	S	S	*	*			trans	-61.6	142.3	171.6	-74.2	167.4	160.4	173.7	-6.5	111.1
15	V	29.6	Very low	28.8	Very low	145 Å²	145	157.5 Å²	157.5	88%	0.879	83%	0.833	S	S	*	*			trans	-139.4	117.5	134.1	-175.2	0	0	0	0	109.2
16	S	26.3	Very low	28.6	Very low	99 Å²	99	156 Å²	156	69%	0.692	84%	0.838	S	S	*	*			trans	-83.2	140.6	173.2	40	0	0	0	0	111.4
17	S	27.4	Very low	28.6	Very low	118 Å²	118	154.1 Å²	154.1	83%	0.825	84%	0.838	S	S	*	*			trans	-178.6	124.4	131.5	31.7	0	0	0	0	114.6
18	S	28.5	Very low	28.4	Very low	106 Å²	106	151.7 Å²	151.7	74%	0.741	83%	0.834	S	S	*	*			trans	70.3	83.3	141.1	-131.2	0	0	0	0	120.4
19	L	27.7	Very low	28.4	Very low	185 Å²	185	153.3 Å²	153.3	97%	0.969	83%	0.833	S	S	*	*			trans	-79.5	110.3	149.9	-90.9	130.8	0	0	0	109.2
20	R	30.2	Very low	28.2	Very low	232 Å²	232	154.3 Å²	154.3	88%	0.875	83%	0.828	S	S	*	*			trans	-85	123	163.2	-80.1	-175	-174.7	-175.8	2.1	109.3	A22	R20-A22 PolarHBondContact O-N 3.47Å
21	A	28.6	Very low	28.2	Very low	100 Å²	100	152 Å²	152	83%	0.826	83%	0.829	S	S	*	*			trans	-64.1	124	171.8	0	0	0	0	0	111.1
22	A	29.9	Very low	28.2	Very low	96 Å²	96	150.3 Å²	150.3	79%	0.793	82%	0.824	S	S	*	*			trans	-104	102.4	164.9	0	0	0	0	0	108.6	R20	R20-A22 PolarHBondContact O-N 3.47Å
23	R	28.7	Very low	28.8	Very low	234 Å²	234	148.6 Å²	148.6	88%	0.883	82%	0.822	S	S	*	*			trans	-70.4	118.3	164.4	-74.8	177.4	177.8	-163.4	-1.8	108.1
24	C	25.6	Very low	28.7	Very low	127 Å²	127	150.3 Å²	150.3	86%	0.858	82%	0.823	S	S	*	*			trans	-100.1	106.9	161.6	-75.1	0	0	0	0	108.5
25	L	27.8	Very low	28.6	Very low	157 Å²	157	145.3 Å²	145.3	82%	0.822	82%	0.818	S	S	*	*			trans	-87.9	127	164.9	-82.5	158.1	0	0	0	108
26	M	29.4	Very low	28.5	Very low	177 Å²	177	144.9 Å²	144.9	87%	0.872	82%	0.815	S	S	*	*			trans	-66.7	154.6	157.3	-68.4	-72.1	160.5	0	0	109.2
27	P	31.4	Very low	28.5	Very low	128 Å²	128	145.9 Å²	145.9	83%	0.831	82%	0.817	S	S	*	*				-142.2	160.8	107.3	33.3	-16.9	0	0	0	115
28	N	26.2	Very low	28.4	Very low	142 Å²	142	146 Å²	146	76%	0.759	82%	0.816	S	S	*	*			trans	-97.3	159.6	-177.6	-164	-0.4	0	0	0	111
29	R	28.7	Very low	28.3	Very low	197 Å²	197	145.3 Å²	145.3	74%	0.743	81%	0.811	S	S	*	*			trans	93.5	117.7	153.1	-66.8	-172.1	167.2	-177	-2	122.6
30	H	26.9	Very low	28.4	Very low	163 Å²	163	144.9 Å²	144.9	76%	0.755	80%	0.804	S	S	*	*				55.8	122.1	129.9	-56.6	-51.6	0	0	0	121.5
31	A	26.6	Very low	28.3	Very low	102 Å²	102	141.2 Å²	141.2	84%	0.843	80%	0.797	S	S	*	*				166.6	127.5	109.1	0	0	0	0	0	112.2
32	A	26.8	Very low	28.1	Very low	94 Å²	94	142 Å²	142	78%	0.777	80%	0.795	S	S	*	*			trans	-89.7	-174	152.4	0	0	0	0	0	108.4
33	P	41.1	Very low	28	Very low	115 Å²	115	144.4 Å²	144.4	75%	0.747	79%	0.792	S	S	*	*			cis	-130.3	-179.8	-14.9	35.6	-17.1	0	0	0	112.2
34	K	27.3	Very low	28	Very low	211 Å²	211	138.7 Å²	138.7	92%	0.917	79%	0.787	S	S	*	*			trans	-172.7	139.7	140.8	-101.3	160.2	-169	-177.3	0	113.5
35	T	25.2	Very low	28	Very low	124 Å²	124	136.2 Å²	136.2	76%	0.761	78%	0.776	S	S	*	*			trans	-83.9	154.3	-175.8	44.7	0	0	0	0	114.8
36	V	27.5	Very low	28	Very low	136 Å²	136	137.2 Å²	137.2	82%	0.824	77%	0.774	S	S	*	*			trans	-159.2	95.8	144.2	178.6	0	0	0	0	107.4
37	T	27.5	Very low	27.9	Very low	119 Å²	119	136.5 Å²	136.5	73%	0.73	77%	0.768	S	S	*	*				55	109.3	102.4	59	0	0	0	0	116.5
38	C	25.3	Very low	28	Very low	121 Å²	121	139.6 Å²	139.6	82%	0.818	77%	0.769	S	S	*	*				81.6	141.6	92.4	-136.6	0	0	0	0	112.7
39	S	26.9	Very low	28.1	Very low	91 Å²	91	142.5 Å²	142.5	64%	0.636	78%	0.775	S	S	*	*			cis	-172.6	156.1	35.4	-37.4	0	0	0	0	111.5
40	H	27.9	Very low	28.3	Very low	177 Å²	177	140.3 Å²	140.3	82%	0.819	78%	0.778	S	S	*	*			trans	160.6	97	130.2	-99.3	-88.5	0	0	0	109.5
41	H	29	Very low	28.4	Very low	154 Å²	154	139.1 Å²	139.1	71%	0.713	78%	0.782	S	S	*	*				53.7	124.1	97.9	-89.3	-34.4	0	0	0	115.5
42	C	24.8	Very low	28.6	Very low	118 Å²	118	142.9 Å²	142.9	80%	0.797	78%	0.782	S	S	*	*				-166.9	119.2	76.7	-161.4	0	0	0	0	109.6
43	M	27.3	Very low	28.5	Very low	146 Å²	146	147.5 Å²	147.5	72%	0.719	79%	0.787	S	S	*	*				53.4	132.2	104.2	-60.5	-78.9	151.7	0	0	114.4
44	S	28	Very low	27.9	Very low	113 Å²	113	152 Å²	152	79%	0.79	79%	0.789	S	S	*	*			cis	-162.5	152.8	33.1	-40.5	0	0	0	0	112
45	A	27	Very low	27.8	Very low	75 Å²	75	149 Å²	149	62%	0.62	78%	0.783	S	S	*	*			trans	-76.9	162.2	166.2	0	0	0	0	0	112.7
46	F	26.7	Very low	28	Very low	178 Å²	178	147.8 Å²	147.8	78%	0.781	79%	0.786	S	S	*	*				164.5	142.5	105.6	-95.4	-67	0	0	0	116.1
47	H	28.3	Very low	28.1	Very low	163 Å²	163	148.6 Å²	148.6	76%	0.755	79%	0.786	S	S	*	*			trans	64.4	116.7	142.4	-77.6	-54.4	0	0	0	124.3
48	K	32.6	Very low	28.2	Very low	192 Å²	192	153.1 Å²	153.1	84%	0.835	80%	0.795	S	S	*	*			trans	-56.9	145.2	145.7	-78.7	176.6	169.8	-179.3	0	112.5
49	K	27.9	Very low	28.2	Very low	204 Å²	204	150.8 Å²	150.8	89%	0.887	79%	0.792	S	S	*	*			trans	-151.6	127.2	145.7	-112	-178	-179	-178.8	0	110.3
50	D	32.6	Very low	28.2	Very low	151 Å²	151	150.1 Å²	150.1	81%	0.807	80%	0.8	S	S	*	*			trans	-76.4	146.1	169.8	-58.5	-64	0	0	0	110.8
51	T	30.6	Very low	28.5	Very low	138 Å²	138	146.7 Å²	146.7	85%	0.847	79%	0.793	S	S	*	*			trans	-156.9	119.6	156.4	-38.8	0	0	0	0	109.6
52	E	29.3	Very low	28.8	Very low	181 Å²	181	142.9 Å²	142.9	85%	0.846	80%	0.796	S	S	*	*			trans	-79.5	142.6	164.1	-75.1	-179.2	122.9	0	0	110.4
53	H	26.2	Very low	29.1	Very low	191 Å²	191	146.8 Å²	146.8	88%	0.884	80%	0.795	S	S	*	*			trans	-162	144.7	140.4	-120.1	-77.7	0	0	0	112.3
54	R	27.4	Very low	29.5	Very low	208 Å²	208	151.6 Å²	151.6	79%	0.785	81%	0.805	S	S	*	*			trans	-67.4	149.5	-176.8	-59	166.1	132.7	173.3	-6.6	114.2
55	D	25.9	Very low	29.8	Very low	148 Å²	148	152.5 Å²	152.5	79%	0.791	81%	0.806	S	S	*	*				157.7	153.3	101.5	-92.1	-42	0	0	0	113.9
56	A	29	Very low	30.1	Very low	99 Å²	99	156.3 Å²	156.3	82%	0.818	82%	0.816	S	S	*	*			trans	93.6	106.9	155	0	0	0	0	0	121.1
57	N	29.7	Very low	30.3	Very low	153 Å²	153	156.9 Å²	156.9	82%	0.818	82%	0.818	S	S	*	*			trans	-35	145.3	154	-95.3	-29.5	0	0	0	115.9
58	F	28.9	Very low	30.5	Very low	214 Å²	214	155 Å²	155	94%	0.939	82%	0.818	S	S	*	*			trans	-165.5	126.6	132.6	-107	-77.1	0	0	0	112.6
59	G	26.9	Very low	30.3	Very low	73 Å²	73	154.1 Å²	154.1	75%	0.753	82%	0.815	S	S	*	*			trans	50.5	126.7	143.4	0	0	0	0	0	122.6
60	G	26.2	Very low	30.6	Very low	77 Å²	77	148.9 Å²	148.9	79%	0.794	80%	0.804	S	S	*	*			trans	-67.3	-158.5	171.6	0	0	0	0	0	115.6
61	P	33.8	Very low	30.7	Very low	104 Å²	104	146.7 Å²	146.7	68%	0.675	80%	0.8	S	S	*	*			cis	-125.2	172.2	20.2	37.4	-19.7	0	0	0	115	Y63	P61-Y63 WeakPolarHBondContact O-CE1 3.33Å
62	G	35.2	Very low	30.7	Very low	75 Å²	75	149.4 Å²	149.4	77%	0.773	80%	0.795	S	S	*	*			trans	-71.3	155.8	-170.5	0	0	0	0	0	117
63	Y	32.2	Very low	31.1	Very low	200 Å²	200	145.6 Å²	145.6	78%	0.784	79%	0.788	S	S	*	*			trans	-135.5	113.2	160	-7.1	-80.7	0	0	0	106.8	P61 T65	P61-Y63 WeakPolarHBondContact O-CE1 3.33Å; Y63-T65 PolarHBondContact O-N 3.12Å
64	R	35.5	Very low	31.6	Very low	247 Å²	247	145.8 Å²	145.8	93%	0.932	78%	0.783	S	S	*	*			trans	-66.8	122.7	163.8	-76.6	-179.4	-179.7	-144	0.2	107.7
65	T	34.8	Very low	32.2	Very low	132 Å²	132	140.7 Å²	140.7	81%	0.81	78%	0.778	S	S	*	*			trans	-131.7	132	157.6	55.4	0	0	0	0	109.7	Y63	Y63-T65 PolarHBondContact O-N 3.12Å
66	N	31.5	Very low	33	Very low	154 Å²	154	140.1 Å²	140.1	82%	0.824	78%	0.781	S	S	*	*			trans	-60.2	129.9	-165.9	-77.9	-34.3	0	0	0	112.6	V68	N66-V68 VanDerWaalsContact C-N 3.31Å; N66-V68 PolarHBondContact O-N 3.48Å
67	K	31	Very low	34	Very low	190 Å²	190	140.4 Å²	140.4	83%	0.826	78%	0.777	S	S	*	*			trans	-66.4	91.3	162.1	-131.3	178.7	-173.3	179.2	0	107.6	F69	K67-F69 PolarHBondContact O-N 3.18Å
68	V	32.7	Very low	35.3	Very low	125 Å²	125	140 Å²	140	76%	0.758	77%	0.77	S	S	*	*			trans	-71.5	99.1	166.3	179.2	0	0	0	0	106.2	N66 S70	N66-V68 VanDerWaalsContact C-N 3.31Å; N66-V68 PolarHBondContact O-N 3.48Å; V68-S70 PolarHBondContact O-N 3.06Å
69	F	29.8	Very low	36.7	Very low	173 Å²	173	133.6 Å²	133.6	76%	0.759	76%	0.756	S	S	*	*			trans	-63.4	93.1	163.8	-109.5	-95.8	0	0	0	106.7	K67 S71	K67-F69 PolarHBondContact O-N 3.18Å; F69-S71 VanDerWaalsContact C-N 3.27Å; F69-S71 PolarHBondContact O-N 2.95Å
70	S	33.3	Very low	38.8	Very low	94 Å²	94	137.3 Å²	137.3	66%	0.657	75%	0.752	S	S	*	*			trans	-71.5	93.7	166.6	-175.9	0	0	0	0	106.6	V68 R72	V68-S70 PolarHBondContact O-N 3.06Å; S70-R72 PolarHBondContact O-N 3.23Å
71	S	35.4	Very low	41.4	Very low	104 Å²	104	137.7 Å²	137.7	73%	0.727	74%	0.735	S	S	*	*			trans	-59	91.1	167.4	-47.9	0	0	0	0	107.4	F69 S73	F69-S71 VanDerWaalsContact C-N 3.27Å; F69-S71 PolarHBondContact O-N 2.95Å; S71-S73 PolarHBondContact O-N 2.64Å
72	R	31.1	Very low	44.2	Very low	196 Å²	196	137.3 Å²	137.3	74%	0.74	73%	0.727	S	S	*	*			trans	-66.1	91.3	166.5	-84.8	-180	175.5	173.7	-1.8	106.9	S70 Y74	S70-R72 PolarHBondContact O-N 3.23Å; R72-Y74 HydrophobicContact CB-CE2 4.31Å; R72-Y74 WeakPolarHBondContact O-CD2 3.35Å; R72-Y74 PolarHBondContact O-N 2.94Å
73	S	36.7	Very low	46.9	Very low	101 Å²	101	133.7 Å²	133.7	71%	0.706	69%	0.691	S	S	*	*			trans	-60	103.7	159.9	44.9	0	0	0	0	107.2	S71 S75	S71-S73 PolarHBondContact O-N 2.64Å; S73-S75 VanDerWaalsContact C-N 3.29Å; S73-S75 PolarHBondContact O-N 3.45Å
74	Y	36.8	Very low	49.9	Very low	195 Å²	195	126.4 Å²	126.4	77%	0.765	66%	0.662	S	S	*	*			trans	-69.9	92.6	168.8	-73.9	-89.3	0	0	0	107.5	R72 T76	R72-Y74 HydrophobicContact CB-CE2 4.31Å; R72-Y74 WeakPolarHBondContact O-CD2 3.35Å; R72-Y74 PolarHBondContact O-N 2.94Å; Y74-T76 PolarHBondContact O-N 3.29Å
75	S	39.6	Very low	52.7	Low	100 Å²	100	118.9 Å²	118.9	70%	0.699	64%	0.64	S	S	*	*			trans	-69.7	109	162.2	-61.3	0	0	0	0	107	S73 S77	S73-S75 VanDerWaalsContact C-N 3.29Å; S73-S75 PolarHBondContact O-N 3.45Å; S75-S77 PolarHBondContact O-N 3.22Å
76	T	42.8	Very low	55.5	Low	136 Å²	136	114.7 Å²	114.7	83%	0.834	62%	0.616	S	S	*	*			trans	-69.3	79.6	164.2	47.8	0	0	0	0	107.8	Y74 E78	Y74-T76 PolarHBondContact O-N 3.29Å; T76-E78 PolarHBondContact O-N 2.99Å; T76-E78 VanDerWaalsContact O-N 3.09Å
77	S	49.5	Very low	58.4	Low	105 Å²	105	113.9 Å²	113.9	73%	0.734	61%	0.605	S	S	*	*			trans	-71.9	99.2	168.7	56.6	0	0	0	0	107.4	S75 A79	S75-S77 PolarHBondContact O-N 3.22Å; S77-A79 PolarHBondContact O-N 3Å; S77-A79 VanDerWaalsContact O-N 3.1Å
78	E	57.4	Low	61.2	Low	144 Å²	144	110 Å²	110	67%	0.673	59%	0.59	S	S	*	*			trans	-52	119.6	161.9	-77.1	176.4	151.8	0	0	107.4	T76 K80	T76-E78 PolarHBondContact O-N 2.99Å; T76-E78 VanDerWaalsContact O-N 3.09Å; E78-K80 PolarHBondContact O-N 3.04Å
79	A	59.4	Low	63.9	Low	80 Å²	80	108.3 Å²	108.3	66%	0.661	58%	0.576	S	S	*	*			trans	-64.3	102	-177.2	0	0	0	0	0	108.4	S77 L81	S77-A79 PolarHBondContact O-N 3Å; S77-A79 VanDerWaalsContact O-N 3.1Å; A79-L81 PolarHBondContact O-N 3.34Å; A79-L81 VanDerWaalsContact O-N 3.15Å
80	K	69.6	Low	66.6	Low	152 Å²	152	100.8 Å²	100.8	66%	0.661	54%	0.544	S	S	*	.			trans	-67	114.4	177.3	-62.3	-175.1	179.7	-174.8	0	108.4	E78 L89	E78-K80 PolarHBondContact O-N 3.04Å; K80-L89 HydrophobicContact CB-CD2 3.98Å
81	L	82.3	Confident	68.6	Low	84 Å²	84	102.9 Å²	102.9	44%	0.44	55%	0.547	S	S	.	.	P	Polyproline II helix	trans	-82.1	141	177.3	-65.8	172.7	0	0	0	110	A79 L90 E108	A79-L81 PolarHBondContact O-N 3.34Å; A79-L81 VanDerWaalsContact O-N 3.15Å; L81-L90 HydrophobicContact CB-CD1 4.19Å; L81-L90 WeakPolarHBondContact O-CB 3.45Å; L81-L90 WeakPolarHBondContact O-CG 3.41Å; L81-L90 PolarHBondContact O-N 3.42Å; L81-E108 HydrophobicContact CD1-CG 4.42Å
82	N	90.8	Very high	70.4	Confident	96 Å²	96	107.4 Å²	107.4	51%	0.513	55%	0.548	S	S	.	.	B	Isolated β-bridge	trans	-90.6	143	175.4	-68	45.8	0	0	0	110.6	W84 K87 L89	N82-W84 PolarHBondContact O-N 2.95Å; N82-K87 PolarHBondContact ND2-O 3.43Å; N82-L89 WeakPolarHBondContact OD1-CD2 3.37Å
83	C	93.4	Very high	72.4	Confident	0 Å²	0	100.2 Å²	100.2	0%	0	53%	0.526	C	S	.	.	P	Polyproline II helix	trans	-59.8	130	174.1	177.3	0	0	0	0	111.2	N85 C86 K87 Q88 L90 C98 C101 Q105	C83-N85 PolarHBondContact O-N 2.94Å; C83-N85 PolarHBondContact SG-N 3.06Å; C83-N85 VanDerWaalsContact SG-N 3.41Å; C83-C86 VanDerWaalsContact SG-SG 3.64Å; C83-K87 VanDerWaalsContact O-CA 3.22Å; C83-K87 WeakPolarHBondContact O-CA 3.4Å; C83-K87 PolarHBondContact O-N 3.03Å; C83-Q88 WeakPolarHBondContact CB-O 3.5Å; C83-Q88 PolarHBondContact N-O 2.9Å; C83-L90 HydrophobicContact CB-CD2 4.3Å; C83-C98 HydrophobicContact CB-CB 4.23Å; C83-C98 VanDerWaalsContact SG-CB 3.58Å; C83-C98 VanDerWaalsContact SG-SG 3.62Å; C83-C101 VanDerWaalsContact SG-SG 3.67Å; C83-Q105 PolarHBondContact SG-NE2 2.92Å; C83-Q105 VanDerWaalsContact SG-NE2 3.38Å
84	W	93.8	Very high	74.5	Confident	46 Å²	46	96.8 Å²	96.8	17%	0.174	50%	0.502	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-27.9	-179.8	67.7	-93.2	0	0	0	113.2	N82 K87 A103 I104 Q105 K152 E153 Y156	N82-W84 PolarHBondContact O-N 2.95Å; W84-K87 PolarHBondContact O-NZ 2.79Å; W84-A103 HydrophobicContact CZ2-CB 4.05Å; W84-I104 PolarHBondContact NE1-O 3.35Å; W84-Q105 VanDerWaalsContact CD1-OE1 3.3Å; W84-K152 HydrophobicContact CD2-CD 4.16Å; W84-K152 HydrophobicContact CE3-CD 3.65Å; W84-K152 HydrophobicContact CE3-CG 4.43Å; W84-K152 HydrophobicContact CH2-CB 4.29Å; W84-K152 HydrophobicContact CH2-CD 4.09Å; W84-K152 HydrophobicContact CH2-CG 4.15Å; W84-K152 HydrophobicContact CZ2-CG 4.38Å; W84-K152 HydrophobicContact CZ3-CD 3.62Å; W84-K152 HydrophobicContact CZ3-CG 4.2Å; W84-E153 HydrophobicContact CH2-CG 4.02Å; W84-E153 HydrophobicContact CZ2-CG 3.76Å; W84-Y156 AromaticContact CD1-CE2 3.64Å; W84-Y156 HydrophobicContact CD2-CE2 4.02Å; W84-Y156 AromaticContact CE2-CE2 3.72Å; W84-Y156 AromaticContact CG-CE2 3.96Å; W84-Y156 HydrophobicContact CG-CE2 3.96Å; W84-Y156 HydrophobicContact CZ2-CD2 4.37Å; W84-Y156 HydrophobicContact CZ2-CE2 4.32Å; W84-Y156 AromaticContact NE1-CD2 3.68Å; W84-Y156 AromaticContact NE1-CE2 3.48Å
85	N	94.5	Very high	77	Confident	89 Å²	89	88.6 Å²	88.6	48%	0.476	47%	0.473	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-63.2	-176.9	-169.7	32.2	0	0	0	111.9	C83 A103	C83-N85 PolarHBondContact O-N 2.94Å; C83-N85 PolarHBondContact SG-N 3.06Å; C83-N85 VanDerWaalsContact SG-N 3.41Å; N85-A103 HydrophobicContact CB-CB 3.91Å
86	C	94.4	Very high	79.5	Confident	45 Å²	45	84.7 Å²	84.7	30%	0.304	44%	0.443	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97.5	-2.2	-173.4	71.2	0	0	0	0	115.5	C83 Q88 C98 C101	C83-C86 VanDerWaalsContact SG-SG 3.64Å; C86-Q88 PolarHBondContact O-N 3Å; C86-C98 PolarHBondContact SG-SG 2.87Å; C86-C101 HydrophobicContact CB-CB 3.91Å; C86-C101 VanDerWaalsContact SG-SG 3.6Å
87	K	92.5	Very high	82	Confident	136 Å²	136	81.1 Å²	81.1	59%	0.591	42%	0.416	S	S	*	.			trans	63.8	-0.9	179.7	-47.8	-52.9	-175.8	-167.9	0	116.7	N82 C83 W84	N82-K87 PolarHBondContact ND2-O 3.43Å; C83-K87 VanDerWaalsContact O-CA 3.22Å; C83-K87 WeakPolarHBondContact O-CA 3.4Å; C83-K87 PolarHBondContact O-N 3.03Å; W84-K87 PolarHBondContact O-NZ 2.79Å
88	Q	90.4	Very high	84.1	Confident	110 Å²	110	76.2 Å²	76.2	51%	0.514	38%	0.382	S	S	.	.	P	Polyproline II helix	trans	-63.2	150.6	171.8	-66.5	-65.5	-12.2	0	0	111.6	C83 C86	C83-Q88 WeakPolarHBondContact CB-O 3.5Å; C83-Q88 PolarHBondContact N-O 2.9Å; C86-Q88 PolarHBondContact O-N 3Å
89	L	89	Confident	85.7	Confident	88 Å²	88	73.6 Å²	73.6	46%	0.461	37%	0.372	S	S	.	.	B	Isolated β-bridge	trans	-66.7	142.5	177.1	-67.9	168.6	0	0	0	110.5	K80 N82	K80-L89 HydrophobicContact CB-CD2 3.98Å; N82-L89 WeakPolarHBondContact OD1-CD2 3.37Å
90	L	85.7	Confident	87.3	Confident	16 Å²	16	73.7 Å²	73.7	8%	0.084	37%	0.368	C	S	.	.	P	Polyproline II helix	trans	-88.5	126.9	170.5	-60.2	175.1	0	0	0	108.8	L81 C83 C98 Q105	L81-L90 HydrophobicContact CB-CD1 4.19Å; L81-L90 WeakPolarHBondContact O-CB 3.45Å; L81-L90 WeakPolarHBondContact O-CG 3.41Å; L81-L90 PolarHBondContact O-N 3.42Å; C83-L90 HydrophobicContact CB-CD2 4.3Å; L90-C98 HydrophobicContact CD2-CB 4.23Å; L90-Q105 HydrophobicContact CD1-CG 4.04Å; L90-Q105 HydrophobicContact CD2-CG 4.13Å
91	D	74.8	Confident	88.4	Confident	137 Å²	137	68.6 Å²	68.6	73%	0.733	35%	0.351	S	S	*	.	S	Bend	trans	-80.3	-17.1	-174.8	-70.7	-25.4	0	0	0	113.5
92	R	74.2	Confident	89	Confident	200 Å²	200	71.1 Å²	71.1	76%	0.755	36%	0.359	S	S	*	.	S	Bend	trans	-137.2	145	-177	-61	-174.8	-176.1	-169.6	0.1	111.5	S95	R92-S95 WeakPolarHBondContact O-CB 3.44Å; R92-S95 PolarHBondContact O-N 2.96Å
93	T	72.3	Confident	89.2	Confident	45 Å²	45	66.6 Å²	66.6	28%	0.276	34%	0.335	S	S	.	.	S	Bend	trans	-126.7	123.2	173.3	42.2	0	0	0	0	109.5	E108	T93-E108 WeakPolarHBondContact CB-OE1 3.11Å; T93-E108 WeakPolarHBondContact CB-OE2 3.44Å
94	P	81.5	Confident	89.3	Confident	29 Å²	29	66.6 Å²	66.6	19%	0.188	34%	0.335	C	S	.	.	S	Bend	cis	-78.2	133.5	-1.5	30.5	-32.8	0	0	0	112.8	E108 A111 I116	P94-E108 WeakPolarHBondContact CA-OE2 3.42Å; P94-E108 HydrophobicContact CB-CB 4.39Å; P94-E108 WeakPolarHBondContact CB-OE2 3.39Å; P94-A111 HydrophobicContact CB-CB 4.49Å; P94-I116 HydrophobicContact CG-CG1 4.22Å
95	S	88.3	Confident	89.3	Confident	22 Å²	22	64.6 Å²	64.6	15%	0.154	33%	0.328	C	S	.	.			trans	-105.8	123	170	175.9	0	0	0	0	110.6	R92 F97 Q105	R92-S95 WeakPolarHBondContact O-CB 3.44Å; R92-S95 PolarHBondContact O-N 2.96Å; S95-F97 PolarHBondContact OG-O 3.48Å; S95-Q105 WeakPolarHBondContact O-CB 3.46Å
96	F	93.3	Very high	89.3	Confident	19 Å²	19	62.9 Å²	62.9	8%	0.083	32%	0.321	C	S	.	.	S	Bend	trans	-80.9	-27.5	177	-63.3	-74.8	0	0	0	113	I104 Q105 I116 L137 L141 V164	F96-I104 CarbonylContact O-C 3.57Å; F96-I104 WeakPolarHBondContact O-CA 3.24Å; F96-Q105 PolarHBondContact O-N 3.47Å; F96-I116 HydrophobicContact CZ-CG2 4.11Å; F96-L137 HydrophobicContact CD2-CD2 3.84Å; F96-L137 HydrophobicContact CE2-CD1 4.31Å; F96-L137 HydrophobicContact CE2-CD2 3.46Å; F96-L137 VanDerWaalsContact CE2-CD2 3.46Å; F96-L137 HydrophobicContact CZ-CD1 4.07Å; F96-L137 HydrophobicContact CZ-CD2 3.86Å; F96-L141 HydrophobicContact CB-CD2 4.05Å; F96-L141 HydrophobicContact CD1-CD1 3.54Å; F96-L141 HydrophobicContact CD1-CD2 4.18Å; F96-L141 HydrophobicContact CD1-CG 4.49Å; F96-L141 HydrophobicContact CE1-CD1 3.78Å; F96-L141 HydrophobicContact CG-CD1 4.11Å; F96-L141 HydrophobicContact CG-CD2 4.38Å; F96-V164 HydrophobicContact CE1-CG2 4.12Å; F96-V164 HydrophobicContact CZ-CG2 4.39Å
97	F	94.6	Very high	89.1	Confident	61 Å²	61	62.6 Å²	62.6	27%	0.268	32%	0.319	S	S	.	.	B	Isolated β-bridge	trans	-139.2	140.5	-175.3	-63.8	-81.4	0	0	0	110.5	S95 D99 I104 L141 F146	S95-F97 PolarHBondContact OG-O 3.48Å; F97-D99 PolarHBondContact O-N 3.17Å; F97-I104 HydrophobicContact CD1-CB 4.13Å; F97-I104 HydrophobicContact CE1-CB 3.98Å; F97-I104 HydrophobicContact CE1-CG1 4.36Å; F97-L141 HydrophobicContact CE2-CD2 3.75Å; F97-L141 HydrophobicContact CZ-CD2 3.64Å; F97-F146 HydrophobicContact CE1-CE1 4.45Å; F97-F146 AromaticContact CE1-CZ 3.92Å; F97-F146 HydrophobicContact CE1-CZ 3.92Å; F97-F146 HydrophobicContact CZ-CZ 4.25Å
98	C	94.1	Very high	88.9	Confident	1 Å²	1	58.9 Å²	58.9	1%	0.007	30%	0.304	C	S	.	.			trans	-70.5	129.6	174.3	175.4	0	0	0	0	111	C83 C86 L90 S100 C101 K102 A103 Q105	C83-C98 HydrophobicContact CB-CB 4.23Å; C83-C98 VanDerWaalsContact SG-CB 3.58Å; C83-C98 VanDerWaalsContact SG-SG 3.62Å; C86-C98 PolarHBondContact SG-SG 2.87Å; L90-C98 HydrophobicContact CD2-CB 4.23Å; C98-S100 VanDerWaalsContact C-N 3.29Å; C98-S100 PolarHBondContact O-N 3.22Å; C98-S100 PolarHBondContact SG-N 2.97Å; C98-C101 VanDerWaalsContact SG-SG 3.61Å; C98-K102 WeakPolarHBondContact O-CA 3.33Å; C98-K102 PolarHBondContact O-N 3.43Å; C98-A103 PolarHBondContact N-O 3.47Å; C98-Q105 HydrophobicContact CB-CG 4.46Å
99	D	91.2	Very high	88.6	Confident	89 Å²	89	62.8 Å²	62.8	48%	0.476	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-32.1	180	-70.9	-54.5	0	0	0	113.6	F97 K102	F97-D99 PolarHBondContact O-N 3.17Å; D99-K102 WeakPolarHBondContact O-CE 3.38Å; D99-K102 PolarHBondContact O-NZ 3.2Å
100	S	92.6	Very high	88.4	Confident	83 Å²	83	62.6 Å²	62.6	58%	0.58	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.5	-49.9	-179	-59.6	0	0	0	0	113.5	C98	C98-S100 VanDerWaalsContact C-N 3.29Å; C98-S100 PolarHBondContact O-N 3.22Å; C98-S100 PolarHBondContact SG-N 2.97Å
101	C	93.8	Very high	88.6	Confident	44 Å²	44	62.6 Å²	62.6	30%	0.297	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	-111.9	-2.3	-172.3	72.1	0	0	0	0	114.8	C83 C86 C98 A103	C83-C101 VanDerWaalsContact SG-SG 3.67Å; C86-C101 HydrophobicContact CB-CB 3.91Å; C86-C101 VanDerWaalsContact SG-SG 3.6Å; C98-C101 VanDerWaalsContact SG-SG 3.61Å; C101-A103 PolarHBondContact O-N 3.3Å; C101-A103 VanDerWaalsContact SG-CB 3.58Å
102	K	93.3	Very high	89.6	Confident	137 Å²	137	57 Å²	57	60%	0.596	32%	0.315	S	S	*	.			trans	58.7	7.8	-178.1	-52.6	-51.6	-173.3	-160	0	115.9	C98 D99 I104	C98-K102 WeakPolarHBondContact O-CA 3.33Å; C98-K102 PolarHBondContact O-N 3.43Å; D99-K102 WeakPolarHBondContact O-CE 3.38Å; D99-K102 PolarHBondContact O-NZ 3.2Å; K102-I104 PolarHBondContact O-N 2.92Å
103	A	94.8	Very high	90.6	Very high	2 Å²	2	48.8 Å²	48.8	2%	0.017	28%	0.284	C	S	.	.	P	Polyproline II helix	trans	-62.2	135.2	172.4	0	0	0	0	0	110.2	W84 N85 C98 C101 Q105	W84-A103 HydrophobicContact CZ2-CB 4.05Å; N85-A103 HydrophobicContact CB-CB 3.91Å; C98-A103 PolarHBondContact N-O 3.47Å; C101-A103 PolarHBondContact O-N 3.3Å; C101-A103 VanDerWaalsContact SG-CB 3.58Å; A103-Q105 PolarHBondContact O-NE2 3.33Å
104	I	95.9	Very high	91.8	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	27%	0.272	C	S	.	.	B	Isolated β-bridge	trans	-60.9	135.2	171.8	-177.8	161.8	0	0	0	109.8	W84 F96 F97 K102 L141 F146 E153 S157 Q160	W84-I104 PolarHBondContact NE1-O 3.35Å; F96-I104 CarbonylContact O-C 3.57Å; F96-I104 WeakPolarHBondContact O-CA 3.24Å; F97-I104 HydrophobicContact CD1-CB 4.13Å; F97-I104 HydrophobicContact CE1-CB 3.98Å; F97-I104 HydrophobicContact CE1-CG1 4.36Å; K102-I104 PolarHBondContact O-N 2.92Å; I104-L141 HydrophobicContact CD1-CD2 3.75Å; I104-L141 HydrophobicContact CG1-CD2 4.44Å; I104-F146 HydrophobicContact CB-CE1 3.94Å; I104-F146 HydrophobicContact CB-CZ 4.27Å; I104-F146 HydrophobicContact CD1-CE1 4.17Å; I104-F146 HydrophobicContact CD1-CE2 4.3Å; I104-F146 HydrophobicContact CD1-CZ 3.83Å; I104-F146 HydrophobicContact CG2-CD1 4.24Å; I104-F146 HydrophobicContact CG2-CE1 3.78Å; I104-E153 HydrophobicContact CG2-CB 3.73Å; I104-E153 HydrophobicContact CG2-CG 3.81Å; I104-S157 VanDerWaalsContact CD1-CA 3.46Å; I104-Q160 HydrophobicContact CD1-CG 4.4Å
105	Q	95	Very high	92.4	Very high	4 Å²	4	51.4 Å²	51.4	2%	0.019	29%	0.289	C	S	.	.	P	Polyproline II helix	trans	-97.8	151.8	-178.7	-62.2	-50.9	-70.4	0	0	111.1	C83 W84 L90 S95 F96 C98 A103 Q160	C83-Q105 PolarHBondContact SG-NE2 2.92Å; C83-Q105 VanDerWaalsContact SG-NE2 3.38Å; W84-Q105 VanDerWaalsContact CD1-OE1 3.3Å; L90-Q105 HydrophobicContact CD1-CG 4.04Å; L90-Q105 HydrophobicContact CD2-CG 4.13Å; S95-Q105 WeakPolarHBondContact O-CB 3.46Å; F96-Q105 PolarHBondContact O-N 3.47Å; C98-Q105 HydrophobicContact CB-CG 4.46Å; A103-Q105 PolarHBondContact O-NE2 3.33Å; Q105-Q160 PolarHBondContact O-NE2 3.2Å
106	P	93.3	Very high	92.7	Very high	53 Å²	53	50.4 Å²	50.4	34%	0.344	28%	0.282	S	S	.	.	P	Polyproline II helix	trans	-59.5	153.4	174	26.3	-35.3	0	0	0	111.2	Y156 Q160	P106-Y156 HydrophobicContact CB-CD1 4.04Å; P106-Y156 HydrophobicContact CB-CE1 3.77Å; P106-Y156 HydrophobicContact CB-CE2 4.36Å; P106-Y156 HydrophobicContact CB-CG 4.45Å; P106-Q160 VanDerWaalsContact C-NE2 3.34Å; P106-Q160 PolarHBondContact O-NE2 3.25Å
107	P	91.8	Very high	92.8	Very high	39 Å²	39	49.6 Å²	49.6	25%	0.253	28%	0.278	S	S	.	.	P	Polyproline II helix	trans	-57.6	139.5	170.9	-19.2	29.9	0	0	0	111.7	Q160 L163	P107-Q160 HydrophobicContact CG-CG 3.96Å; P107-L163 HydrophobicContact CB-CD2 3.74Å
108	E	87.6	Confident	92.7	Very high	58 Å²	58	52.5 Å²	52.5	27%	0.271	30%	0.297	S	S	.	.	P	Polyproline II helix	trans	-78.1	125.8	176.1	-176.4	178	178.8	0	0	110.4	L81 T93 P94 A111	L81-E108 HydrophobicContact CD1-CG 4.42Å; T93-E108 WeakPolarHBondContact CB-OE1 3.11Å; T93-E108 WeakPolarHBondContact CB-OE2 3.44Å; P94-E108 WeakPolarHBondContact CA-OE2 3.42Å; P94-E108 HydrophobicContact CB-CB 4.39Å; P94-E108 WeakPolarHBondContact CB-OE2 3.39Å; E108-A111 HydrophobicContact CB-CB 4.02Å; E108-A111 HydrophobicContact CG-CB 4.14Å
109	E	83.4	Confident	92.7	Very high	191 Å²	191	54.1 Å²	54.1	89%	0.893	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.1	129.1	175.3	-64.7	-178.8	-171	0	0	110.1	A111	E109-A111 VanDerWaalsContact C-N 3.33Å; E109-A111 PolarHBondContact O-N 3.41Å
110	G	84.5	Confident	92.8	Very high	85 Å²	85	56 Å²	56	88%	0.876	32%	0.317	S	S	*	.	T	Hydrogen-bonded Turn	trans	83	-1.9	178.7	0	0	0	0	0	115.6	S112	G110-S112 PolarHBondContact O-N 2.98Å
111	A	90.6	Very high	92.7	Very high	15 Å²	15	56.9 Å²	56.9	12%	0.124	31%	0.309	C	S	.	.			trans	-64.4	130.9	171.8	0	0	0	0	0	110.8	P94 E108 E109 I116	P94-A111 HydrophobicContact CB-CB 4.49Å; E108-A111 HydrophobicContact CB-CB 4.02Å; E108-A111 HydrophobicContact CG-CB 4.14Å; E109-A111 VanDerWaalsContact C-N 3.33Å; E109-A111 PolarHBondContact O-N 3.41Å; A111-I116 HydrophobicContact CB-CD1 4.17Å; A111-I116 HydrophobicContact CB-CG1 4.16Å
112	S	94.9	Very high	92.7	Very high	20 Å²	20	57.4 Å²	57.4	14%	0.14	31%	0.311	C	S	.	.			trans	-70.5	151.1	177.8	74.9	0	0	0	0	111.6	G110 F114 K115 I116 Y180	G110-S112 PolarHBondContact O-N 2.98Å; S112-F114 PolarHBondContact O-N 3.26Å; S112-K115 PolarHBondContact O-N 3.25Å; S112-K115 WeakPolarHBondContact OG-CG 3.48Å; S112-K115 PolarHBondContact OG-N 2.63Å; S112-I116 WeakPolarHBondContact O-CG1 3.3Å; S112-I116 PolarHBondContact O-N 3.44Å; S112-Y180 WeakPolarHBondContact CA-OH 3.5Å
113	Y	96.8	Very high	92.6	Very high	27 Å²	27	50.9 Å²	50.9	11%	0.106	28%	0.283	C	S	.	.	H	α-helix	trans	-61.3	-31.3	177.3	-63.9	-17.8	0	0	0	112	I116 L117 L163 K166 A167 T170 Y180	Y113-I116 HydrophobicContact CD1-CD1 3.97Å; Y113-I116 PolarHBondContact O-N 3.02Å; Y113-L117 WeakPolarHBondContact O-CB 3.49Å; Y113-L117 PolarHBondContact O-N 3.05Å; Y113-L163 HydrophobicContact CD1-CD1 4.48Å; Y113-L163 HydrophobicContact CE1-CD1 3.86Å; Y113-K166 HydrophobicContact CE2-CG 4.49Å; Y113-K166 VanDerWaalsContact OH-CD 3.27Å; Y113-K166 WeakPolarHBondContact OH-CD 3.21Å; Y113-K166 WeakPolarHBondContact OH-CE 3.29Å; Y113-K166 PolarHBondContact OH-NZ 3.02Å; Y113-A167 HydrophobicContact CD1-CB 3.72Å; Y113-A167 HydrophobicContact CD2-CB 4.32Å; Y113-A167 HydrophobicContact CE1-CB 4.44Å; Y113-A167 HydrophobicContact CG-CB 3.66Å; Y113-T170 HydrophobicContact CD2-CG2 3.91Å; Y113-T170 HydrophobicContact CE2-CG2 3.99Å; Y113-Y180 AromaticContact CD2-CD1 3.95Å; Y113-Y180 HydrophobicContact CD2-CD1 3.95Å; Y113-Y180 AromaticContact CD2-CD2 3.93Å; Y113-Y180 HydrophobicContact CD2-CD2 3.93Å; Y113-Y180 AromaticContact CD2-CE1 3.67Å; Y113-Y180 HydrophobicContact CD2-CE1 3.67Å; Y113-Y180 AromaticContact CD2-CE2 3.66Å; Y113-Y180 HydrophobicContact CD2-CE2 3.66Å; Y113-Y180 HydrophobicContact CD2-CG 4.07Å; Y113-Y180 AromaticContact CD2-CZ 3.52Å; Y113-Y180 AromaticContact CE2-CD2 3.97Å; Y113-Y180 HydrophobicContact CE2-CD2 3.97Å; Y113-Y180 AromaticContact CE2-CE2 3.77Å; Y113-Y180 HydrophobicContact CE2-CE2 3.77Å; Y113-Y180 HydrophobicContact CE2-CG 4.46Å; Y113-Y180 AromaticContact CG-CE1 3.8Å; Y113-Y180 HydrophobicContact CG-CE1 3.8Å; Y113-Y180 HydrophobicContact CG-CE2 4.15Å; Y113-Y180 AromaticContact CG-CZ 3.61Å; Y113-Y180 PolarHBondContact N-OH 3.37Å
114	F	95.8	Very high	92.4	Very high	5 Å²	5	54.6 Å²	54.6	2%	0.022	31%	0.305	C	S	.	.	H	α-helix	trans	-61.9	-44.5	173	-63.1	-84	0	0	0	111.6	S112 L117 D118 C119 D120 Y121 L125 L171 R177 Y180 M181 L184	S112-F114 PolarHBondContact O-N 3.26Å; F114-L117 CarbonylContact O-C 3.19Å; F114-D118 PolarHBondContact O-N 2.97Å; F114-C119 PolarHBondContact O-N 3.24Å; F114-D120 WeakPolarHBondContact CD1-O 3.46Å; F114-Y121 AromaticContact CD2-CD2 3.54Å; F114-Y121 HydrophobicContact CD2-CD2 3.54Å; F114-Y121 HydrophobicContact CD2-CE2 4Å; F114-Y121 AromaticContact CE2-CD2 3.67Å; F114-Y121 HydrophobicContact CE2-CD2 3.67Å; F114-Y121 AromaticContact CE2-CE2 3.79Å; F114-Y121 HydrophobicContact CE2-CE2 3.79Å; F114-Y121 HydrophobicContact CG-CD2 4.02Å; F114-Y121 HydrophobicContact CZ-CD2 4.24Å; F114-Y121 HydrophobicContact CZ-CE2 4.48Å; F114-L125 HydrophobicContact CE1-CD1 4.01Å; F114-L125 HydrophobicContact CE1-CD2 4.4Å; F114-L171 HydrophobicContact CD1-CD1 4.03Å; F114-L171 HydrophobicContact CD1-CD2 4.3Å; F114-L171 HydrophobicContact CD2-CD2 4.34Å; F114-L171 HydrophobicContact CE1-CD1 4.32Å; F114-L171 HydrophobicContact CE1-CD2 3.89Å; F114-L171 HydrophobicContact CE2-CD2 3.9Å; F114-L171 HydrophobicContact CG-CD1 4.31Å; F114-L171 HydrophobicContact CZ-CD2 3.66Å; F114-R177 HydrophobicContact CZ-CG 4.31Å; F114-Y180 HydrophobicContact CD2-CD1 4.37Å; F114-Y180 AromaticContact CD2-CE1 3.85Å; F114-Y180 HydrophobicContact CD2-CE1 3.85Å; F114-Y180 AromaticContact CE2-CD1 3.79Å; F114-Y180 HydrophobicContact CE2-CD1 3.79Å; F114-Y180 AromaticContact CE2-CE1 3.73Å; F114-Y180 HydrophobicContact CE2-CE1 3.73Å; F114-M181 HydrophobicContact CE2-CG 3.77Å; F114-M181 HydrophobicContact CZ-CG 3.59Å; F114-M181 HydrophobicContact CZ-SD 3.86Å; F114-L184 HydrophobicContact CD2-CD1 4.22Å; F114-L184 HydrophobicContact CE2-CD1 4.18Å
115	K	94.6	Very high	92.1	Very high	124 Å²	124	55.7 Å²	55.7	54%	0.539	31%	0.311	S	S	.	.	H	α-helix	trans	-66.3	-42.4	174.5	-72.3	-174.8	177.4	-169.7	0	112.4	S112 L117 D118	S112-K115 PolarHBondContact O-N 3.25Å; S112-K115 WeakPolarHBondContact OG-CG 3.48Å; S112-K115 PolarHBondContact OG-N 2.63Å; K115-L117 VanDerWaalsContact C-N 3.34Å; K115-L117 PolarHBondContact O-N 2.83Å; K115-D118 PolarHBondContact O-N 3.1Å
116	I	94.6	Very high	92	Very high	2 Å²	2	59.2 Å²	59.2	1%	0.01	33%	0.33	C	S	.	.	H	α-helix	trans	-62	-42.7	179.2	-70.3	157.9	0	0	0	111.3	P94 F96 A111 S112 Y113 D118 L163 V164 A167	P94-I116 HydrophobicContact CG-CG1 4.22Å; F96-I116 HydrophobicContact CZ-CG2 4.11Å; A111-I116 HydrophobicContact CB-CD1 4.17Å; A111-I116 HydrophobicContact CB-CG1 4.16Å; S112-I116 WeakPolarHBondContact O-CG1 3.3Å; S112-I116 PolarHBondContact O-N 3.44Å; Y113-I116 HydrophobicContact CD1-CD1 3.97Å; Y113-I116 PolarHBondContact O-N 3.02Å; I116-D118 VanDerWaalsContact C-N 3.33Å; I116-L163 HydrophobicContact CD1-CD1 4.08Å; I116-L163 HydrophobicContact CD1-CD2 3.73Å; I116-L163 HydrophobicContact CD1-CG 3.94Å; I116-V164 HydrophobicContact CG2-CG2 4.12Å; I116-A167 HydrophobicContact CG2-CB 4.36Å
117	L	95.4	Very high	92	Very high	1 Å²	1	60.1 Å²	60.1	1%	0.005	33%	0.334	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.8	9.4	179.3	-71.7	169.9	0	0	0	113.7	Y113 F114 K115 C119 L130 R133 L137 V164 A167 L171	Y113-L117 WeakPolarHBondContact O-CB 3.49Å; Y113-L117 PolarHBondContact O-N 3.05Å; F114-L117 CarbonylContact O-C 3.19Å; K115-L117 VanDerWaalsContact C-N 3.34Å; K115-L117 PolarHBondContact O-N 2.83Å; L117-C119 VanDerWaalsContact C-N 3.33Å; L117-C119 PolarHBondContact O-N 3.33Å; L117-L130 HydrophobicContact CB-CD1 4.06Å; L117-L130 HydrophobicContact CD1-CD1 3.83Å; L117-L130 HydrophobicContact CG-CD1 4.47Å; L117-R133 WeakPolarHBondContact O-CG 3.24Å; L117-L137 HydrophobicContact CD2-CD1 4.04Å; L117-V164 HydrophobicContact CD2-CG1 4.33Å; L117-A167 VanDerWaalsContact CD1-C 3.49Å; L117-A167 HydrophobicContact CD1-CB 3.64Å; L117-A167 HydrophobicContact CG-CB 4.05Å; L117-L171 HydrophobicContact CB-CD1 4.49Å; L117-L171 HydrophobicContact CD1-CD1 3.91Å; L117-L171 HydrophobicContact CD1-CG 4.45Å
118	D	93.4	Very high	92.2	Very high	123 Å²	123	64.4 Å²	64.4	66%	0.658	35%	0.351	S	S	*	.	T	Hydrogen-bonded Turn	trans	48.4	52.8	174.3	-165.9	33.1	0	0	0	112.6	F114 K115 I116	F114-D118 PolarHBondContact O-N 2.97Å; K115-D118 PolarHBondContact O-N 3.1Å; I116-D118 VanDerWaalsContact C-N 3.33Å
119	C	93.6	Very high	92.6	Very high	35 Å²	35	68.6 Å²	68.6	24%	0.236	37%	0.368	C	S	.	.			trans	-132.8	160	178.8	70.9	0	0	0	0	111.5	F114 L117	F114-C119 PolarHBondContact O-N 3.24Å; L117-C119 VanDerWaalsContact C-N 3.33Å; L117-C119 PolarHBondContact O-N 3.33Å
120	D	92	Very high	93.2	Very high	127 Å²	127	59.7 Å²	59.7	68%	0.679	33%	0.327	S	S	*	.			trans	-63.5	146	-178.2	-57.8	-42.7	0	0	0	111.6	F114 T122 L125	F114-D120 WeakPolarHBondContact CD1-O 3.46Å; D120-T122 HydrophobicContact CB-CG2 4.19Å; D120-T122 PolarHBondContact O-N 2.66Å; D120-L125 WeakPolarHBondContact O-CD2 3.31Å
121	Y	92.3	Very high	93.8	Very high	102 Å²	102	59.9 Å²	59.9	40%	0.4	31%	0.305	S	S	.	.	S	Bend	trans	-77.5	75.3	172.6	-176.1	-97.5	0	0	0	109.4	F114 M181 L184 E185	F114-Y121 AromaticContact CD2-CD2 3.54Å; F114-Y121 HydrophobicContact CD2-CD2 3.54Å; F114-Y121 HydrophobicContact CD2-CE2 4Å; F114-Y121 AromaticContact CE2-CD2 3.67Å; F114-Y121 HydrophobicContact CE2-CD2 3.67Å; F114-Y121 AromaticContact CE2-CE2 3.79Å; F114-Y121 HydrophobicContact CE2-CE2 3.79Å; F114-Y121 HydrophobicContact CG-CD2 4.02Å; F114-Y121 HydrophobicContact CZ-CD2 4.24Å; F114-Y121 HydrophobicContact CZ-CE2 4.48Å; Y121-M181 HydrophobicContact CD1-CE 4.39Å; Y121-M181 HydrophobicContact CE1-CE 3.93Å; Y121-M181 HydrophobicContact CE2-CE 4.3Å; Y121-M181 HydrophobicContact CE2-CG 4.26Å; Y121-L184 HydrophobicContact CE2-CD1 3.71Å; Y121-E185 PolarHBondContact OH-OE1 3.04Å
122	T	91.9	Very high	94.1	Very high	55 Å²	55	65.3 Å²	65.3	34%	0.337	33%	0.325	S	S	.	.			trans	-135.1	151.5	177.6	59.5	0	0	0	0	110.3	D120 T124 L125	D120-T122 HydrophobicContact CB-CG2 4.19Å; D120-T122 PolarHBondContact O-N 2.66Å; T122-T124 PolarHBondContact OG1-O 2.74Å; T122-L125 WeakPolarHBondContact OG1-CD2 3.22Å
123	F	93.3	Very high	94.2	Very high	1 Å²	1	67.5 Å²	67.5	0%	0.004	33%	0.331	C	S	.	.	S	Bend	trans	-75.7	-38	175.2	-179.6	-99.9	0	0	0	110.4	L125 P174 R177 M181 T236 I239 D240 L243 M258	F123-L125 PolarHBondContact O-N 3.36Å; F123-P174 WeakPolarHBondContact CE2-O 3.48Å; F123-P174 HydrophobicContact CZ-CB 3.94Å; F123-R177 HydrophobicContact CD2-CG 4.42Å; F123-R177 WeakPolarHBondContact O-CD 3.34Å; F123-R177 PolarHBondContact O-NH1 3.05Å; F123-M181 HydrophobicContact CB-CE 4.3Å; F123-M181 HydrophobicContact CB-SD 3.88Å; F123-M181 HydrophobicContact CD2-SD 4.06Å; F123-M181 HydrophobicContact CG-SD 4.5Å; F123-T236 HydrophobicContact CD1-CG2 4.18Å; F123-T236 HydrophobicContact CE1-CG2 3.56Å; F123-T236 WeakPolarHBondContact CE1-O 3.42Å; F123-I239 HydrophobicContact CD1-CB 4.39Å; F123-I239 HydrophobicContact CD1-CG2 4.01Å; F123-I239 HydrophobicContact CD2-CG2 3.99Å; F123-I239 HydrophobicContact CE1-CB 4Å; F123-I239 HydrophobicContact CE1-CG2 3.82Å; F123-I239 HydrophobicContact CE2-CG2 3.81Å; F123-I239 HydrophobicContact CG-CG2 4.08Å; F123-I239 HydrophobicContact CZ-CB 4.21Å; F123-I239 HydrophobicContact CZ-CD1 4.35Å; F123-I239 HydrophobicContact CZ-CG2 3.72Å; F123-D240 HydrophobicContact CB-CB 4.33Å; F123-D240 VanDerWaalsContact CB-OD1 3.31Å; F123-D240 WeakPolarHBondContact CB-OD1 3.38Å; F123-D240 HydrophobicContact CD1-CB 4.04Å; F123-D240 PolarHBondContact N-OD1 3.01Å; F123-L243 HydrophobicContact CB-CD1 3.79Å; F123-L243 HydrophobicContact CD2-CD1 3.93Å; F123-L243 HydrophobicContact CG-CD1 4.03Å; F123-M258 HydrophobicContact CZ-CE 4.31Å; F123-M258 HydrophobicContact CZ-SD 4.5Å
124	T	89.6	Confident	94.2	Very high	80 Å²	80	68.6 Å²	68.6	49%	0.491	34%	0.335	S	S	.	.	S	Bend	trans	-78.5	104.1	169.8	-53.8	0	0	0	0	111	T122 D240	T122-T124 PolarHBondContact OG1-O 2.74Å; T124-D240 PolarHBondContact N-OD1 3.31Å; T124-D240 PolarHBondContact OG1-OD1 3.37Å; T124-D240 PolarHBondContact OG1-OD2 3.23Å
125	L	90.3	Very high	94.3	Very high	23 Å²	23	71.7 Å²	71.7	12%	0.12	35%	0.351	C	S	.	.			trans	-112.6	144.2	176.9	-64	-180	0	0	0	112.7	F114 D120 T122 F123 T127 L171	F114-L125 HydrophobicContact CE1-CD1 4.01Å; F114-L125 HydrophobicContact CE1-CD2 4.4Å; D120-L125 WeakPolarHBondContact O-CD2 3.31Å; T122-L125 WeakPolarHBondContact OG1-CD2 3.22Å; F123-L125 PolarHBondContact O-N 3.36Å; L125-T127 PolarHBondContact O-N 3Å; L125-L171 HydrophobicContact CD1-CB 4.24Å; L125-L171 HydrophobicContact CD1-CD1 4.44Å
126	D	93.1	Very high	94.4	Very high	78 Å²	78	69.8 Å²	69.8	42%	0.417	34%	0.344	S	S	.	.			trans	-72.3	102.9	165.6	-179.2	-22	0	0	0	110.2	H128 K129 L130	D126-H128 PolarHBondContact O-N 3.38Å; D126-H128 WeakPolarHBondContact OD1-CA 3.36Å; D126-H128 WeakPolarHBondContact OD1-CB 3.35Å; D126-H128 PolarHBondContact OD1-N 2.91Å; D126-K129 HydrophobicContact CB-CB 4.11Å; D126-K129 HydrophobicContact CB-CD 4.01Å; D126-K129 HydrophobicContact CB-CG 4.23Å; D126-K129 PolarHBondContact O-N 3.11Å; D126-K129 PolarHBondContact OD1-N 3.46Å; D126-K129 VanDerWaalsContact OD2-CD 3.24Å; D126-K129 WeakPolarHBondContact OD2-CD 3.29Å; D126-K129 WeakPolarHBondContact OD2-CE 3.39Å; D126-K129 VanDerWaalsContact OD2-CG 3.25Å; D126-K129 WeakPolarHBondContact OD2-CG 3.49Å; D126-K129 IonicContact OD2-NZ 3.89Å; D126-L130 WeakPolarHBondContact O-CB 3.4Å; D126-L130 PolarHBondContact O-N 3.11Å
127	T	93.2	Very high	94.5	Very high	71 Å²	71	69.9 Å²	69.9	44%	0.436	35%	0.345	S	S	.	.	H	α-helix	trans	-65.8	-26.1	-178.3	55.8	0	0	0	0	112.9	L125 Q131 L172	L125-T127 PolarHBondContact O-N 3Å; T127-Q131 WeakPolarHBondContact O-CB 3.48Å; T127-Q131 PolarHBondContact O-N 3.47Å; T127-L172 HydrophobicContact CG2-CD1 4.37Å
128	H	95.3	Very high	94.6	Very high	129 Å²	129	70.8 Å²	70.8	60%	0.597	35%	0.349	S	S	*	.	H	α-helix	trans	-74.4	-42.8	177.9	-179.5	-95.3	0	0	0	111.2	D126 L130 Q131 K132	D126-H128 PolarHBondContact O-N 3.38Å; D126-H128 WeakPolarHBondContact OD1-CA 3.36Å; D126-H128 WeakPolarHBondContact OD1-CB 3.35Å; D126-H128 PolarHBondContact OD1-N 2.91Å; H128-L130 VanDerWaalsContact C-N 3.34Å; H128-Q131 PolarHBondContact O-N 2.93Å; H128-K132 WeakPolarHBondContact O-CB 3.13Å; H128-K132 PolarHBondContact O-N 2.74Å
129	K	95.3	Very high	94.8	Very high	146 Å²	146	73.6 Å²	73.6	64%	0.635	35%	0.351	S	S	*	.	H	α-helix	trans	-60.4	-44.9	170.4	-76.5	177.1	-169.2	171.9	0	111.3	D126 Q131 K132 R133	D126-K129 HydrophobicContact CB-CB 4.11Å; D126-K129 HydrophobicContact CB-CD 4.01Å; D126-K129 HydrophobicContact CB-CG 4.23Å; D126-K129 PolarHBondContact O-N 3.11Å; D126-K129 PolarHBondContact OD1-N 3.46Å; D126-K129 VanDerWaalsContact OD2-CD 3.24Å; D126-K129 WeakPolarHBondContact OD2-CD 3.29Å; D126-K129 WeakPolarHBondContact OD2-CE 3.39Å; D126-K129 VanDerWaalsContact OD2-CG 3.25Å; D126-K129 WeakPolarHBondContact OD2-CG 3.49Å; D126-K129 IonicContact OD2-NZ 3.89Å; K129-Q131 PolarHBondContact O-N 2.92Å; K129-K132 PolarHBondContact O-N 3.45Å; K129-R133 WeakPolarHBondContact O-CB 3.36Å; K129-R133 PolarHBondContact O-N 2.83Å
130	L	96.2	Very high	94.8	Very high	5 Å²	5	75.1 Å²	75.1	3%	0.026	36%	0.359	C	S	.	.	H	α-helix	trans	-57.3	-48.6	177.2	-171	71.7	0	0	0	111.5	L117 D126 H128 R133 Y134 Y168 L171	L117-L130 HydrophobicContact CB-CD1 4.06Å; L117-L130 HydrophobicContact CD1-CD1 3.83Å; L117-L130 HydrophobicContact CG-CD1 4.47Å; D126-L130 WeakPolarHBondContact O-CB 3.4Å; D126-L130 PolarHBondContact O-N 3.11Å; H128-L130 VanDerWaalsContact C-N 3.34Å; L130-R133 PolarHBondContact O-N 2.85Å; L130-Y134 WeakPolarHBondContact O-CB 3.35Å; L130-Y134 PolarHBondContact O-N 3.06Å; L130-Y168 HydrophobicContact CD2-CD2 4.17Å; L130-Y168 HydrophobicContact CD2-CE2 4.28Å; L130-Y168 HydrophobicContact CG-CD2 4.04Å; L130-Y168 HydrophobicContact CG-CE2 4.24Å; L130-L171 HydrophobicContact CD1-CB 4.31Å; L130-L171 HydrophobicContact CD1-CD1 4.26Å; L130-L171 HydrophobicContact CD2-CB 3.95Å
131	Q	97.3	Very high	95	Very high	89 Å²	89	69 Å²	69	42%	0.416	33%	0.326	S	S	.	.	H	α-helix	trans	-63.2	-43.4	178.4	-174.4	-179.2	12.1	0	0	112	T127 H128 K129 R133 Y134 L135 Y168	T127-Q131 WeakPolarHBondContact O-CB 3.48Å; T127-Q131 PolarHBondContact O-N 3.47Å; H128-Q131 PolarHBondContact O-N 2.93Å; K129-Q131 PolarHBondContact O-N 2.92Å; Q131-R133 VanDerWaalsContact C-N 3.32Å; Q131-R133 PolarHBondContact O-N 3.34Å; Q131-Y134 WeakPolarHBondContact O-CB 3.49Å; Q131-Y134 PolarHBondContact O-N 3.03Å; Q131-L135 HydrophobicContact CG-CD1 4.29Å; Q131-L135 WeakPolarHBondContact O-CG 3.3Å; Q131-L135 PolarHBondContact O-N 3.48Å; Q131-Y168 HydrophobicContact CB-CE2 4.26Å
132	K	97.4	Very high	95.2	Very high	128 Å²	128	67.6 Å²	67.6	56%	0.557	32%	0.323	S	S	*	.	H	α-helix	trans	-58.4	-45.9	176.9	-177.7	-179.4	179.6	-177.7	0	111.1	H128 K129 L135 Q136	H128-K132 WeakPolarHBondContact O-CB 3.13Å; H128-K132 PolarHBondContact O-N 2.74Å; K129-K132 PolarHBondContact O-N 3.45Å; K132-L135 PolarHBondContact O-N 3.01Å; K132-Q136 VanDerWaalsContact O-CG 3.31Å; K132-Q136 WeakPolarHBondContact O-CG 3.27Å; K132-Q136 PolarHBondContact O-N 3.45Å
133	R	96.7	Very high	95.3	Very high	66 Å²	66	67.4 Å²	67.4	25%	0.249	32%	0.323	C	S	.	.	H	α-helix	trans	-67	-43.5	179.6	-178.2	46.3	176.2	169.6	0.9	112.1	L117 K129 L130 Q131 L135 Q136 L137	L117-R133 WeakPolarHBondContact O-CG 3.24Å; K129-R133 WeakPolarHBondContact O-CB 3.36Å; K129-R133 PolarHBondContact O-N 2.83Å; L130-R133 PolarHBondContact O-N 2.85Å; Q131-R133 VanDerWaalsContact C-N 3.32Å; Q131-R133 PolarHBondContact O-N 3.34Å; R133-L135 VanDerWaalsContact C-N 3.35Å; R133-L135 PolarHBondContact O-N 3.46Å; R133-Q136 WeakPolarHBondContact O-CB 3.48Å; R133-Q136 PolarHBondContact O-N 2.89Å; R133-L137 HydrophobicContact CG-CD1 4.49Å; R133-L137 WeakPolarHBondContact O-CG 3.5Å; R133-L137 PolarHBondContact O-N 3.24Å
134	Y	97.7	Very high	95.5	Very high	50 Å²	50	72.7 Å²	72.7	20%	0.196	35%	0.351	C	S	.	.	H	α-helix	trans	-53.1	-49.9	171.8	163.7	-105.6	0	0	0	112.2	L130 Q131 Q136 L137 Q138 V164 N165 Y168	L130-Y134 WeakPolarHBondContact O-CB 3.35Å; L130-Y134 PolarHBondContact O-N 3.06Å; Q131-Y134 WeakPolarHBondContact O-CB 3.49Å; Q131-Y134 PolarHBondContact O-N 3.03Å; Y134-Q136 PolarHBondContact O-N 2.9Å; Y134-L137 PolarHBondContact O-N 3.16Å; Y134-Q138 HydrophobicContact CD2-CG 4.12Å; Y134-Q138 HydrophobicContact CE1-CG 4.46Å; Y134-Q138 HydrophobicContact CE2-CG 3.54Å; Y134-Q138 PolarHBondContact O-N 3.49Å; Y134-V164 HydrophobicContact CD2-CG1 3.78Å; Y134-V164 HydrophobicContact CE2-CG1 4.21Å; Y134-N165 WeakPolarHBondContact CE2-OD1 3.48Å; Y134-N165 PolarHBondContact OH-OD1 3.38Å; Y134-N165 VanDerWaalsContact OH-OD1 3.05Å; Y134-Y168 HydrophobicContact CD1-CD1 4.01Å; Y134-Y168 HydrophobicContact CD1-CD2 4.27Å; Y134-Y168 HydrophobicContact CD1-CE1 4.05Å; Y134-Y168 HydrophobicContact CD1-CE2 4.3Å; Y134-Y168 HydrophobicContact CD1-CG 4.12Å; Y134-Y168 VanDerWaalsContact CD2-CB 3.47Å; Y134-Y168 AromaticContact CD2-CD1 3.92Å; Y134-Y168 HydrophobicContact CD2-CD1 3.92Å; Y134-Y168 HydrophobicContact CD2-CD2 4.16Å; Y134-Y168 AromaticContact CD2-CG 3.58Å; Y134-Y168 HydrophobicContact CD2-CG 3.58Å; Y134-Y168 HydrophobicContact CE1-CD1 4.11Å; Y134-Y168 HydrophobicContact CE1-CE1 4.16Å; Y134-Y168 AromaticContact CE2-CD1 4Å; Y134-Y168 HydrophobicContact CE2-CD1 4Å; Y134-Y168 HydrophobicContact CE2-CG 4.09Å; Y134-Y168 AromaticContact CG-CD1 3.92Å; Y134-Y168 HydrophobicContact CG-CD1 3.92Å; Y134-Y168 AromaticContact CG-CD2 3.74Å; Y134-Y168 HydrophobicContact CG-CD2 3.74Å; Y134-Y168 HydrophobicContact CG-CE1 4.35Å; Y134-Y168 HydrophobicContact CG-CE2 4.19Å; Y134-Y168 AromaticContact CG-CG 3.58Å; Y134-Y168 HydrophobicContact CG-CG 3.58Å
135	L	97.7	Very high	95.8	Very high	71 Å²	71	73.2 Å²	73.2	37%	0.372	35%	0.351	S	S	.	.	H	α-helix	trans	-64.3	-38.8	179.4	-69.9	173.7	0	0	0	112.4	Q131 K132 R133 R139	Q131-L135 HydrophobicContact CG-CD1 4.29Å; Q131-L135 WeakPolarHBondContact O-CG 3.3Å; Q131-L135 PolarHBondContact O-N 3.48Å; K132-L135 PolarHBondContact O-N 3.01Å; R133-L135 VanDerWaalsContact C-N 3.35Å; R133-L135 PolarHBondContact O-N 3.46Å; L135-R139 WeakPolarHBondContact O-CB 3.31Å; L135-R139 VanDerWaalsContact O-CG 3.23Å; L135-R139 WeakPolarHBondContact O-CG 3.49Å; L135-R139 PolarHBondContact O-N 3.02Å
136	Q	96.8	Very high	96.1	Very high	83 Å²	83	72.8 Å²	72.8	39%	0.388	35%	0.348	S	S	.	.	H	α-helix	trans	-60.6	-47.3	175.1	-74.2	171.2	-12.5	0	0	111.6	K132 R133 Y134 R139 T140	K132-Q136 VanDerWaalsContact O-CG 3.31Å; K132-Q136 WeakPolarHBondContact O-CG 3.27Å; K132-Q136 PolarHBondContact O-N 3.45Å; R133-Q136 WeakPolarHBondContact O-CB 3.48Å; R133-Q136 PolarHBondContact O-N 2.89Å; Y134-Q136 PolarHBondContact O-N 2.9Å; Q136-R139 PolarHBondContact O-N 3.42Å; Q136-T140 PolarHBondContact O-N 3.05Å
137	L	96.4	Very high	96.1	Very high	5 Å²	5	72.4 Å²	72.4	3%	0.026	35%	0.351	C	S	.	.	H	α-helix	trans	-63.7	-49.5	178.8	-72.1	175.6	0	0	0	111.2	F96 L117 R133 Y134 R139 T140 L141 V164	F96-L137 HydrophobicContact CD2-CD2 3.84Å; F96-L137 HydrophobicContact CE2-CD1 4.31Å; F96-L137 HydrophobicContact CE2-CD2 3.46Å; F96-L137 VanDerWaalsContact CE2-CD2 3.46Å; F96-L137 HydrophobicContact CZ-CD1 4.07Å; F96-L137 HydrophobicContact CZ-CD2 3.86Å; L117-L137 HydrophobicContact CD2-CD1 4.04Å; R133-L137 HydrophobicContact CG-CD1 4.49Å; R133-L137 WeakPolarHBondContact O-CG 3.5Å; R133-L137 PolarHBondContact O-N 3.24Å; Y134-L137 PolarHBondContact O-N 3.16Å; L137-R139 VanDerWaalsContact C-N 3.32Å; L137-R139 PolarHBondContact O-N 3.32Å; L137-T140 PolarHBondContact O-N 3.43Å; L137-T140 PolarHBondContact O-OG1 3Å; L137-L141 HydrophobicContact CB-CD1 4.2Å; L137-L141 HydrophobicContact CD2-CD1 4.32Å; L137-L141 WeakPolarHBondContact O-CB 3.44Å; L137-L141 WeakPolarHBondContact O-CG 3.42Å; L137-L141 PolarHBondContact O-N 3.45Å; L137-V164 HydrophobicContact CB-CG1 3.98Å; L137-V164 HydrophobicContact CB-CG2 4.35Å; L137-V164 HydrophobicContact CD1-CG1 4.17Å; L137-V164 HydrophobicContact CD1-CG2 4.07Å
138	Q	97	Very high	96.3	Very high	20 Å²	20	77.6 Å²	77.6	9%	0.093	37%	0.371	C	S	.	.	H	α-helix	trans	-57.1	-43.5	178.4	-83.1	-61.7	-21.4	0	0	112.2	Y134 T140 L141 H142 S161 V164 N165	Y134-Q138 HydrophobicContact CD2-CG 4.12Å; Y134-Q138 HydrophobicContact CE1-CG 4.46Å; Y134-Q138 HydrophobicContact CE2-CG 3.54Å; Y134-Q138 PolarHBondContact O-N 3.49Å; Q138-T140 PolarHBondContact O-N 2.97Å; Q138-T140 VanDerWaalsContact O-N 3.12Å; Q138-L141 PolarHBondContact O-N 2.98Å; Q138-H142 VanDerWaalsContact O-CB 3.24Å; Q138-H142 WeakPolarHBondContact O-CB 3.3Å; Q138-H142 PolarHBondContact O-N 3.02Å; Q138-S161 VanDerWaalsContact CD-OG 3.32Å; Q138-S161 PolarHBondContact NE2-O 2.96Å; Q138-S161 PolarHBondContact NE2-OG 3.42Å; Q138-S161 PolarHBondContact OE1-OG 3.22Å; Q138-V164 HydrophobicContact CG-CG1 4.47Å; Q138-N165 VanDerWaalsContact NE2-CG 3.33Å; Q138-N165 PolarHBondContact NE2-OD1 2.98Å
139	R	96.9	Very high	96.3	Very high	182 Å²	182	76.9 Å²	76.9	69%	0.687	37%	0.366	S	S	*	.	H	α-helix	trans	-56.1	-32.4	176.5	-76.6	172.2	-170.8	172.8	3.3	113.7	L135 Q136 L137 N145	L135-R139 WeakPolarHBondContact O-CB 3.31Å; L135-R139 VanDerWaalsContact O-CG 3.23Å; L135-R139 WeakPolarHBondContact O-CG 3.49Å; L135-R139 PolarHBondContact O-N 3.02Å; Q136-R139 PolarHBondContact O-N 3.42Å; L137-R139 VanDerWaalsContact C-N 3.32Å; L137-R139 PolarHBondContact O-N 3.32Å; R139-N145 PolarHBondContact O-ND2 2.92Å
140	T	95.6	Very high	96.3	Very high	66 Å²	66	72.6 Å²	72.6	41%	0.405	35%	0.354	S	S	.	.	H	α-helix	trans	-90.7	-32.1	-179.7	59.6	0	0	0	0	113.3	Q136 L137 Q138 F146	Q136-T140 PolarHBondContact O-N 3.05Å; L137-T140 PolarHBondContact O-N 3.43Å; L137-T140 PolarHBondContact O-OG1 3Å; Q138-T140 PolarHBondContact O-N 2.97Å; Q138-T140 VanDerWaalsContact O-N 3.12Å; T140-F146 WeakPolarHBondContact O-CE2 3.33Å
141	L	96	Very high	96.4	Very high	0 Å²	0	77.9 Å²	77.9	0%	0	39%	0.387	C	S	.	.	H	α-helix	trans	-101.6	-6.4	-170.7	-61.2	170.4	0	0	0	113.9	F96 F97 I104 L137 Q138 S157 Q160 V164	F96-L141 HydrophobicContact CB-CD2 4.05Å; F96-L141 HydrophobicContact CD1-CD1 3.54Å; F96-L141 HydrophobicContact CD1-CD2 4.18Å; F96-L141 HydrophobicContact CD1-CG 4.49Å; F96-L141 HydrophobicContact CE1-CD1 3.78Å; F96-L141 HydrophobicContact CG-CD1 4.11Å; F96-L141 HydrophobicContact CG-CD2 4.38Å; F97-L141 HydrophobicContact CE2-CD2 3.75Å; F97-L141 HydrophobicContact CZ-CD2 3.64Å; I104-L141 HydrophobicContact CD1-CD2 3.75Å; I104-L141 HydrophobicContact CG1-CD2 4.44Å; L137-L141 HydrophobicContact CB-CD1 4.2Å; L137-L141 HydrophobicContact CD2-CD1 4.32Å; L137-L141 WeakPolarHBondContact O-CB 3.44Å; L137-L141 WeakPolarHBondContact O-CG 3.42Å; L137-L141 PolarHBondContact O-N 3.45Å; Q138-L141 PolarHBondContact O-N 2.98Å; L141-S157 PolarHBondContact O-OG 3.25Å; L141-Q160 HydrophobicContact CD1-CB 4.28Å; L141-Q160 HydrophobicContact CD2-CB 4.33Å; L141-V164 HydrophobicContact CD1-CG2 4.03Å
142	H	95.3	Very high	96.3	Very high	72 Å²	72	77.6 Å²	77.6	33%	0.333	38%	0.384	S	S	.	.			trans	-59.4	134.8	-176	-164.5	-94.3	0	0	0	111.9	Q138 D144 N145 F146	Q138-H142 VanDerWaalsContact O-CB 3.24Å; Q138-H142 WeakPolarHBondContact O-CB 3.3Å; Q138-H142 PolarHBondContact O-N 3.02Å; H142-D144 IonicContact CE1-OD1 3.34Å; H142-D144 PolarHBondContact CE1-OD1 3Å; H142-D144 IonicContact CE1-OD2 3.15Å; H142-D144 PolarHBondContact CE1-OD2 3.4Å; H142-D144 WeakPolarHBondContact ND1-CB 3.47Å; H142-D144 PolarHBondContact ND1-N 2.9Å; H142-D144 IonicContact ND1-OD1 3.51Å; H142-D144 IonicContact ND1-OD2 3.32Å; H142-D144 PolarHBondContact ND1-OD2 3.39Å; H142-D144 PolarHBondContact O-N 3.28Å; H142-D144 VanDerWaalsContact O-N 3.09Å; H142-N145 WeakPolarHBondContact O-CB 3.36Å; H142-N145 PolarHBondContact O-N 3.25Å; H142-F146 WeakPolarHBondContact O-CD2 3.28Å
143	P	95.5	Very high	96.3	Very high	50 Å²	50	73.1 Å²	73.1	33%	0.325	37%	0.365	S	S	.	.	G	3₁₀ helix	trans	-51.7	-33.9	-178.7	-30.6	37.3	0	0	0	115.1	N145 F146 S147 S157	P143-N145 PolarHBondContact O-N 3.46Å; P143-F146 WeakPolarHBondContact O-CA 3.49Å; P143-F146 PolarHBondContact O-N 2.98Å; P143-S147 PolarHBondContact O-N 3.08Å; P143-S157 VanDerWaalsContact CA-OG 3.25Å; P143-S157 WeakPolarHBondContact CA-OG 3.23Å
144	D	96.3	Very high	96.3	Very high	112 Å²	112	73.7 Å²	73.7	60%	0.599	37%	0.371	S	S	*	.	G	3₁₀ helix	trans	-57	-34.3	179.3	-63.9	-0.4	0	0	0	112.8	H142 F146 S147	H142-D144 IonicContact CE1-OD1 3.34Å; H142-D144 PolarHBondContact CE1-OD1 3Å; H142-D144 IonicContact CE1-OD2 3.15Å; H142-D144 PolarHBondContact CE1-OD2 3.4Å; H142-D144 WeakPolarHBondContact ND1-CB 3.47Å; H142-D144 PolarHBondContact ND1-N 2.9Å; H142-D144 IonicContact ND1-OD1 3.51Å; H142-D144 IonicContact ND1-OD2 3.32Å; H142-D144 PolarHBondContact ND1-OD2 3.39Å; H142-D144 PolarHBondContact O-N 3.28Å; H142-D144 VanDerWaalsContact O-N 3.09Å; D144-F146 PolarHBondContact O-N 3.26Å; D144-S147 PolarHBondContact O-N 3.42Å; D144-S147 PolarHBondContact O-OG 2.93Å
145	N	95.2	Very high	96.3	Very high	91 Å²	91	77 Å²	77	49%	0.487	39%	0.387	S	S	.	.	G	3₁₀ helix	trans	-68.2	-18	177.6	-64.3	-15.8	0	0	0	112.9	R139 H142 P143	R139-N145 PolarHBondContact O-ND2 2.92Å; H142-N145 WeakPolarHBondContact O-CB 3.36Å; H142-N145 PolarHBondContact O-N 3.25Å; P143-N145 PolarHBondContact O-N 3.46Å
146	F	96.8	Very high	96.2	Very high	15 Å²	15	75.3 Å²	75.3	7%	0.066	38%	0.377	C	S	.	.	G	3₁₀ helix	trans	-111.1	3	-174.8	-62.2	-95.6	0	0	0	112.8	F97 I104 T140 H142 P143 D144 Q148 K149 E153 Q154 S157	F97-F146 HydrophobicContact CE1-CE1 4.45Å; F97-F146 AromaticContact CE1-CZ 3.92Å; F97-F146 HydrophobicContact CE1-CZ 3.92Å; F97-F146 HydrophobicContact CZ-CZ 4.25Å; I104-F146 HydrophobicContact CB-CE1 3.94Å; I104-F146 HydrophobicContact CB-CZ 4.27Å; I104-F146 HydrophobicContact CD1-CE1 4.17Å; I104-F146 HydrophobicContact CD1-CE2 4.3Å; I104-F146 HydrophobicContact CD1-CZ 3.83Å; I104-F146 HydrophobicContact CG2-CD1 4.24Å; I104-F146 HydrophobicContact CG2-CE1 3.78Å; T140-F146 WeakPolarHBondContact O-CE2 3.33Å; H142-F146 WeakPolarHBondContact O-CD2 3.28Å; P143-F146 WeakPolarHBondContact O-CA 3.49Å; P143-F146 PolarHBondContact O-N 2.98Å; D144-F146 PolarHBondContact O-N 3.26Å; F146-Q148 PolarHBondContact O-N 3.27Å; F146-K149 HydrophobicContact CB-CB 4.2Å; F146-K149 HydrophobicContact CB-CG 4.17Å; F146-K149 HydrophobicContact CD1-CB 4.29Å; F146-K149 HydrophobicContact CD1-CG 3.92Å; F146-K149 HydrophobicContact CG-CG 4.42Å; F146-K149 VanDerWaalsContact O-CB 3.28Å; F146-K149 WeakPolarHBondContact O-CB 3.43Å; F146-K149 PolarHBondContact O-N 3.43Å; F146-E153 HydrophobicContact CD1-CB 4.15Å; F146-Q154 HydrophobicContact CB-CG 4.31Å; F146-Q154 WeakPolarHBondContact O-CG 3.48Å; F146-S157 WeakPolarHBondContact CD2-OG 3.43Å
147	S	94.8	Very high	96.3	Very high	70 Å²	70	71.4 Å²	71.4	49%	0.49	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.4	-30.1	-179	55.4	0	0	0	0	114.8	P143 D144 Q154	P143-S147 PolarHBondContact O-N 3.08Å; D144-S147 PolarHBondContact O-N 3.42Å; D144-S147 PolarHBondContact O-OG 2.93Å; S147-Q154 PolarHBondContact O-NE2 3.2Å
148	Q	95.9	Very high	96.3	Very high	180 Å²	180	72.6 Å²	72.6	84%	0.841	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103	7.5	177.7	-57.4	-59.6	-35.5	0	0	113.7	F146	F146-Q148 PolarHBondContact O-N 3.27Å
149	K	95.6	Very high	96.3	Very high	114 Å²	114	74.2 Å²	74.2	50%	0.496	39%	0.385	S	S	.	.	S	Bend	trans	-91.6	176.5	-179.9	-63.3	-68.2	-174	175.6	0	111.2	F146 E153 Q154	F146-K149 HydrophobicContact CB-CB 4.2Å; F146-K149 HydrophobicContact CB-CG 4.17Å; F146-K149 HydrophobicContact CD1-CB 4.29Å; F146-K149 HydrophobicContact CD1-CG 3.92Å; F146-K149 HydrophobicContact CG-CG 4.42Å; F146-K149 VanDerWaalsContact O-CB 3.28Å; F146-K149 WeakPolarHBondContact O-CB 3.43Å; F146-K149 PolarHBondContact O-N 3.43Å; K149-E153 HydrophobicContact CB-CB 3.98Å; K149-Q154 PolarHBondContact O-NE2 3.43Å
150	S	96.4	Very high	96.3	Very high	55 Å²	55	65.8 Å²	65.8	39%	0.385	35%	0.354	S	S	.	.			trans	-60.8	152.5	177.1	65.7	0	0	0	0	111.8	K152 E153 Q154	S150-K152 PolarHBondContact O-N 2.87Å; S150-K152 VanDerWaalsContact O-N 3.15Å; S150-E153 PolarHBondContact N-OE2 3.44Å; S150-E153 PolarHBondContact O-N 3.25Å; S150-E153 VanDerWaalsContact OG-CG 3.24Å; S150-E153 WeakPolarHBondContact OG-CG 3.18Å; S150-E153 PolarHBondContact OG-N 3.42Å; S150-E153 PolarHBondContact OG-OE2 3.04Å; S150-Q154 PolarHBondContact O-N 2.99Å
151	V	96.6	Very high	96.3	Very high	117 Å²	117	63 Å²	63	71%	0.709	34%	0.337	S	S	*	.	H	α-helix	trans	-52.9	-39.6	179.3	177.4	0	0	0	0	111.6	Q154 E155	V151-Q154 WeakPolarHBondContact O-CB 3.32Å; V151-Q154 PolarHBondContact O-N 3.45Å; V151-E155 PolarHBondContact O-N 2.8Å
152	K	96.2	Very high	96.4	Very high	82 Å²	82	65.8 Å²	65.8	36%	0.357	36%	0.36	S	S	.	.	H	α-helix	trans	-66	-38.7	178.8	-171	164.6	-178.8	176	0	112.9	W84 S150 Y156	W84-K152 HydrophobicContact CD2-CD 4.16Å; W84-K152 HydrophobicContact CE3-CD 3.65Å; W84-K152 HydrophobicContact CE3-CG 4.43Å; W84-K152 HydrophobicContact CH2-CB 4.29Å; W84-K152 HydrophobicContact CH2-CD 4.09Å; W84-K152 HydrophobicContact CH2-CG 4.15Å; W84-K152 HydrophobicContact CZ2-CG 4.38Å; W84-K152 HydrophobicContact CZ3-CD 3.62Å; W84-K152 HydrophobicContact CZ3-CG 4.2Å; S150-K152 PolarHBondContact O-N 2.87Å; S150-K152 VanDerWaalsContact O-N 3.15Å; K152-Y156 HydrophobicContact CD-CE2 4.17Å; K152-Y156 VanDerWaalsContact CE-CZ 3.46Å; K152-Y156 WeakPolarHBondContact CE-OH 3.49Å; K152-Y156 HydrophobicContact CG-CD2 4.14Å; K152-Y156 HydrophobicContact CG-CE2 3.58Å; K152-Y156 WeakPolarHBondContact O-CD2 3.47Å; K152-Y156 VanDerWaalsContact O-CG 3.27Å; K152-Y156 PolarHBondContact O-N 3.23Å; K152-Y156 VanDerWaalsContact O-N 3.08Å
153	E	96.6	Very high	96.4	Very high	34 Å²	34	64 Å²	64	16%	0.159	35%	0.353	C	S	.	.	H	α-helix	trans	-70.3	-36.2	174.6	-70	173.9	107.6	0	0	112.1	W84 I104 F146 K149 S150 Y156 S157	W84-E153 HydrophobicContact CH2-CG 4.02Å; W84-E153 HydrophobicContact CZ2-CG 3.76Å; I104-E153 HydrophobicContact CG2-CB 3.73Å; I104-E153 HydrophobicContact CG2-CG 3.81Å; F146-E153 HydrophobicContact CD1-CB 4.15Å; K149-E153 HydrophobicContact CB-CB 3.98Å; S150-E153 PolarHBondContact N-OE2 3.44Å; S150-E153 PolarHBondContact O-N 3.25Å; S150-E153 VanDerWaalsContact OG-CG 3.24Å; S150-E153 WeakPolarHBondContact OG-CG 3.18Å; S150-E153 PolarHBondContact OG-N 3.42Å; S150-E153 PolarHBondContact OG-OE2 3.04Å; E153-Y156 PolarHBondContact O-N 2.88Å; E153-S157 VanDerWaalsContact O-CB 3.3Å; E153-S157 WeakPolarHBondContact O-CB 3.39Å; E153-S157 PolarHBondContact O-N 3Å
154	Q	97.3	Very high	96.5	Very high	79 Å²	79	61.7 Å²	61.7	37%	0.369	34%	0.337	S	S	.	.	H	α-helix	trans	-61.9	-45.6	173.7	-69.2	178.9	30.3	0	0	111.5	F146 S147 K149 S150 V151 S157 G158	F146-Q154 HydrophobicContact CB-CG 4.31Å; F146-Q154 WeakPolarHBondContact O-CG 3.48Å; S147-Q154 PolarHBondContact O-NE2 3.2Å; K149-Q154 PolarHBondContact O-NE2 3.43Å; S150-Q154 PolarHBondContact O-N 2.99Å; V151-Q154 WeakPolarHBondContact O-CB 3.32Å; V151-Q154 PolarHBondContact O-N 3.45Å; Q154-S157 PolarHBondContact O-N 3.14Å; Q154-G158 PolarHBondContact O-N 3.26Å
155	E	97.2	Very high	96.5	Very high	118 Å²	118	58.6 Å²	58.6	55%	0.551	32%	0.321	S	S	*	.	H	α-helix	trans	-58.8	-51.5	175.6	-176.1	-177.8	-178.9	0	0	111.3	V151 S157 G158 S159	V151-E155 PolarHBondContact O-N 2.8Å; E155-S157 VanDerWaalsContact C-N 3.33Å; E155-S157 PolarHBondContact O-N 2.92Å; E155-G158 PolarHBondContact O-N 3.03Å; E155-G158 VanDerWaalsContact O-N 3.15Å; E155-S159 PolarHBondContact O-N 3.16Å; E155-S159 PolarHBondContact O-OG 3.02Å
156	Y	96.9	Very high	96.6	Very high	37 Å²	37	60.1 Å²	60.1	15%	0.145	32%	0.323	C	S	.	.	H	α-helix	trans	-63.9	-36.8	179.9	-65.5	-21.8	0	0	0	113.2	W84 P106 K152 E153 S159 Q160	W84-Y156 AromaticContact CD1-CE2 3.64Å; W84-Y156 HydrophobicContact CD2-CE2 4.02Å; W84-Y156 AromaticContact CE2-CE2 3.72Å; W84-Y156 AromaticContact CG-CE2 3.96Å; W84-Y156 HydrophobicContact CG-CE2 3.96Å; W84-Y156 HydrophobicContact CZ2-CD2 4.37Å; W84-Y156 HydrophobicContact CZ2-CE2 4.32Å; W84-Y156 AromaticContact NE1-CD2 3.68Å; W84-Y156 AromaticContact NE1-CE2 3.48Å; P106-Y156 HydrophobicContact CB-CD1 4.04Å; P106-Y156 HydrophobicContact CB-CE1 3.77Å; P106-Y156 HydrophobicContact CB-CE2 4.36Å; P106-Y156 HydrophobicContact CB-CG 4.45Å; K152-Y156 HydrophobicContact CD-CE2 4.17Å; K152-Y156 VanDerWaalsContact CE-CZ 3.46Å; K152-Y156 WeakPolarHBondContact CE-OH 3.49Å; K152-Y156 HydrophobicContact CG-CD2 4.14Å; K152-Y156 HydrophobicContact CG-CE2 3.58Å; K152-Y156 WeakPolarHBondContact O-CD2 3.47Å; K152-Y156 VanDerWaalsContact O-CG 3.27Å; K152-Y156 PolarHBondContact O-N 3.23Å; K152-Y156 VanDerWaalsContact O-N 3.08Å; E153-Y156 PolarHBondContact O-N 2.88Å; Y156-S159 PolarHBondContact O-N 3.36Å; Y156-Q160 VanDerWaalsContact O-CB 3.23Å; Y156-Q160 WeakPolarHBondContact O-CB 3.39Å; Y156-Q160 WeakPolarHBondContact O-CG 3.37Å; Y156-Q160 PolarHBondContact O-N 2.88Å
157	S	97.5	Very high	96.6	Very high	0 Å²	0	59.4 Å²	59.4	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-61.5	-45.5	172.3	168.7	0	0	0	0	111.8	I104 L141 P143 F146 E153 Q154 E155 S161	I104-S157 VanDerWaalsContact CD1-CA 3.46Å; L141-S157 PolarHBondContact O-OG 3.25Å; P143-S157 VanDerWaalsContact CA-OG 3.25Å; P143-S157 WeakPolarHBondContact CA-OG 3.23Å; F146-S157 WeakPolarHBondContact CD2-OG 3.43Å; E153-S157 VanDerWaalsContact O-CB 3.3Å; E153-S157 WeakPolarHBondContact O-CB 3.39Å; E153-S157 PolarHBondContact O-N 3Å; Q154-S157 PolarHBondContact O-N 3.14Å; E155-S157 VanDerWaalsContact C-N 3.33Å; E155-S157 PolarHBondContact O-N 2.92Å; S157-S161 VanDerWaalsContact O-CB 3.25Å; S157-S161 WeakPolarHBondContact O-CB 3.31Å; S157-S161 PolarHBondContact O-N 2.84Å
158	G	97	Very high	96.8	Very high	31 Å²	31	57.5 Å²	57.5	32%	0.32	30%	0.302	S	S	.	.	H	α-helix	trans	-57.7	-52	174.5	0	0	0	0	0	112.5	Q154 E155 S161 A162	Q154-G158 PolarHBondContact O-N 3.26Å; E155-G158 PolarHBondContact O-N 3.03Å; E155-G158 VanDerWaalsContact O-N 3.15Å; G158-S161 PolarHBondContact O-N 2.85Å; G158-A162 WeakPolarHBondContact O-CB 3.37Å; G158-A162 PolarHBondContact O-N 3.49Å
159	S	96.4	Very high	96.8	Very high	53 Å²	53	56 Å²	56	37%	0.371	29%	0.293	S	S	.	.	H	α-helix	trans	-63.8	-43.2	-179.4	-55.9	0	0	0	0	112.7	E155 Y156 A162 L163	E155-S159 PolarHBondContact O-N 3.16Å; E155-S159 PolarHBondContact O-OG 3.02Å; Y156-S159 PolarHBondContact O-N 3.36Å; S159-A162 PolarHBondContact O-N 2.77Å; S159-L163 WeakPolarHBondContact O-CB 3.44Å; S159-L163 PolarHBondContact O-N 2.86Å
160	Q	96.4	Very high	96.9	Very high	6 Å²	6	51.9 Å²	51.9	3%	0.028	28%	0.277	C	S	.	.	H	α-helix	trans	-66.4	-44.9	178.4	-72	-76.1	20	0	0	111.7	I104 Q105 P106 P107 L141 Y156 A162 L163 V164	I104-Q160 HydrophobicContact CD1-CG 4.4Å; Q105-Q160 PolarHBondContact O-NE2 3.2Å; P106-Q160 VanDerWaalsContact C-NE2 3.34Å; P106-Q160 PolarHBondContact O-NE2 3.25Å; P107-Q160 HydrophobicContact CG-CG 3.96Å; L141-Q160 HydrophobicContact CD1-CB 4.28Å; L141-Q160 HydrophobicContact CD2-CB 4.33Å; Y156-Q160 VanDerWaalsContact O-CB 3.23Å; Y156-Q160 WeakPolarHBondContact O-CB 3.39Å; Y156-Q160 WeakPolarHBondContact O-CG 3.37Å; Y156-Q160 PolarHBondContact O-N 2.88Å; Q160-A162 VanDerWaalsContact C-N 3.33Å; Q160-A162 PolarHBondContact O-N 2.86Å; Q160-L163 PolarHBondContact O-N 3.38Å; Q160-V164 WeakPolarHBondContact O-CG2 3.48Å; Q160-V164 PolarHBondContact O-N 3.35Å
161	S	96.9	Very high	96.9	Very high	8 Å²	8	49.2 Å²	49.2	6%	0.056	26%	0.259	C	S	.	.	H	α-helix	trans	-61.2	-42.6	176.5	179.4	0	0	0	0	111.3	Q138 S157 G158 V164 N165	Q138-S161 VanDerWaalsContact CD-OG 3.32Å; Q138-S161 PolarHBondContact NE2-O 2.96Å; Q138-S161 PolarHBondContact NE2-OG 3.42Å; Q138-S161 PolarHBondContact OE1-OG 3.22Å; S157-S161 VanDerWaalsContact O-CB 3.25Å; S157-S161 WeakPolarHBondContact O-CB 3.31Å; S157-S161 PolarHBondContact O-N 2.84Å; G158-S161 PolarHBondContact O-N 2.85Å; S161-V164 PolarHBondContact O-N 3.07Å; S161-N165 WeakPolarHBondContact O-CB 3.5Å; S161-N165 PolarHBondContact O-N 3.31Å; S161-N165 PolarHBondContact O-ND2 3.25Å
162	A	96.7	Very high	96.9	Very high	57 Å²	57	46.5 Å²	46.5	47%	0.471	24%	0.24	S	C	.	.	H	α-helix	trans	-62.8	-42.1	175.4	0	0	0	0	0	112.5	G158 S159 Q160 N165 K166	G158-A162 WeakPolarHBondContact O-CB 3.37Å; G158-A162 PolarHBondContact O-N 3.49Å; S159-A162 PolarHBondContact O-N 2.77Å; Q160-A162 VanDerWaalsContact C-N 3.33Å; Q160-A162 PolarHBondContact O-N 2.86Å; A162-N165 WeakPolarHBondContact O-CB 3.41Å; A162-N165 PolarHBondContact O-N 3.5Å; A162-K166 PolarHBondContact O-N 3.48Å
163	L	96.6	Very high	96.8	Very high	36 Å²	36	48.9 Å²	48.9	19%	0.188	25%	0.251	C	S	.	.	H	α-helix	trans	-63.4	-47.2	176.7	178.4	60.4	0	0	0	111.8	P107 Y113 I116 S159 Q160 N165 K166 A167	P107-L163 HydrophobicContact CB-CD2 3.74Å; Y113-L163 HydrophobicContact CD1-CD1 4.48Å; Y113-L163 HydrophobicContact CE1-CD1 3.86Å; I116-L163 HydrophobicContact CD1-CD1 4.08Å; I116-L163 HydrophobicContact CD1-CD2 3.73Å; I116-L163 HydrophobicContact CD1-CG 3.94Å; S159-L163 WeakPolarHBondContact O-CB 3.44Å; S159-L163 PolarHBondContact O-N 2.86Å; Q160-L163 PolarHBondContact O-N 3.38Å; L163-N165 VanDerWaalsContact C-N 3.29Å; L163-N165 PolarHBondContact O-N 2.69Å; L163-K166 PolarHBondContact O-N 3.01Å; L163-K166 VanDerWaalsContact O-N 3.15Å; L163-A167 WeakPolarHBondContact O-CB 3.48Å; L163-A167 PolarHBondContact O-N 3.28Å
164	V	97	Very high	96.6	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-60.8	-39.8	176.8	169.3	0	0	0	0	111.1	F96 I116 L117 Y134 L137 Q138 L141 Q160 S161 A167 Y168	F96-V164 HydrophobicContact CE1-CG2 4.12Å; F96-V164 HydrophobicContact CZ-CG2 4.39Å; I116-V164 HydrophobicContact CG2-CG2 4.12Å; L117-V164 HydrophobicContact CD2-CG1 4.33Å; Y134-V164 HydrophobicContact CD2-CG1 3.78Å; Y134-V164 HydrophobicContact CE2-CG1 4.21Å; L137-V164 HydrophobicContact CB-CG1 3.98Å; L137-V164 HydrophobicContact CB-CG2 4.35Å; L137-V164 HydrophobicContact CD1-CG1 4.17Å; L137-V164 HydrophobicContact CD1-CG2 4.07Å; Q138-V164 HydrophobicContact CG-CG1 4.47Å; L141-V164 HydrophobicContact CD1-CG2 4.03Å; Q160-V164 WeakPolarHBondContact O-CG2 3.48Å; Q160-V164 PolarHBondContact O-N 3.35Å; S161-V164 PolarHBondContact O-N 3.07Å; V164-A167 PolarHBondContact O-N 3.16Å; V164-Y168 VanDerWaalsContact O-CB 3.32Å; V164-Y168 WeakPolarHBondContact O-CB 3.19Å; V164-Y168 PolarHBondContact O-N 3.29Å
165	N	97.2	Very high	96.5	Very high	47 Å²	47	47.7 Å²	47.7	25%	0.251	25%	0.25	S	S	.	.	H	α-helix	trans	-61.8	-45.4	173.8	-74.8	-24.4	0	0	0	112.1	Y134 Q138 S161 A162 L163 Y168 K169	Y134-N165 WeakPolarHBondContact CE2-OD1 3.48Å; Y134-N165 PolarHBondContact OH-OD1 3.38Å; Y134-N165 VanDerWaalsContact OH-OD1 3.05Å; Q138-N165 VanDerWaalsContact NE2-CG 3.33Å; Q138-N165 PolarHBondContact NE2-OD1 2.98Å; S161-N165 WeakPolarHBondContact O-CB 3.5Å; S161-N165 PolarHBondContact O-N 3.31Å; S161-N165 PolarHBondContact O-ND2 3.25Å; A162-N165 WeakPolarHBondContact O-CB 3.41Å; A162-N165 PolarHBondContact O-N 3.5Å; L163-N165 VanDerWaalsContact C-N 3.29Å; L163-N165 PolarHBondContact O-N 2.69Å; N165-Y168 PolarHBondContact O-N 3.03Å; N165-K169 WeakPolarHBondContact O-CB 3.45Å; N165-K169 WeakPolarHBondContact O-CG 3.36Å; N165-K169 PolarHBondContact O-N 2.91Å
166	K	97	Very high	96.4	Very high	123 Å²	123	43.7 Å²	43.7	54%	0.535	24%	0.235	S	C	.	.	H	α-helix	trans	-63.6	-47.3	178.2	-172.9	178.7	179	-168	0	110.9	Y113 A162 L163 Y168 K169 T170	Y113-K166 HydrophobicContact CE2-CG 4.49Å; Y113-K166 VanDerWaalsContact OH-CD 3.27Å; Y113-K166 WeakPolarHBondContact OH-CD 3.21Å; Y113-K166 WeakPolarHBondContact OH-CE 3.29Å; Y113-K166 PolarHBondContact OH-NZ 3.02Å; A162-K166 PolarHBondContact O-N 3.48Å; L163-K166 PolarHBondContact O-N 3.01Å; L163-K166 VanDerWaalsContact O-N 3.15Å; K166-Y168 VanDerWaalsContact C-N 3.34Å; K166-Y168 PolarHBondContact O-N 3.35Å; K166-K169 PolarHBondContact O-N 3.26Å; K166-T170 WeakPolarHBondContact O-CB 3.39Å; K166-T170 PolarHBondContact O-N 3.32Å; K166-T170 PolarHBondContact O-OG1 2.94Å
167	A	97	Very high	96.3	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-57	-48	176.5	0	0	0	0	0	110.9	Y113 I116 L117 L163 V164 T170 L171	Y113-A167 HydrophobicContact CD1-CB 3.72Å; Y113-A167 HydrophobicContact CD2-CB 4.32Å; Y113-A167 HydrophobicContact CE1-CB 4.44Å; Y113-A167 HydrophobicContact CG-CB 3.66Å; I116-A167 HydrophobicContact CG2-CB 4.36Å; L117-A167 VanDerWaalsContact CD1-C 3.49Å; L117-A167 HydrophobicContact CD1-CB 3.64Å; L117-A167 HydrophobicContact CG-CB 4.05Å; L163-A167 WeakPolarHBondContact O-CB 3.48Å; L163-A167 PolarHBondContact O-N 3.28Å; V164-A167 PolarHBondContact O-N 3.16Å; A167-T170 PolarHBondContact O-N 2.93Å; A167-L171 WeakPolarHBondContact O-CB 3.49Å; A167-L171 WeakPolarHBondContact O-CG 3.45Å; A167-L171 PolarHBondContact O-N 3.17Å
168	Y	97.9	Very high	96.2	Very high	30 Å²	30	42.3 Å²	42.3	12%	0.118	23%	0.23	C	C	.	.	H	α-helix	trans	-63.8	-49.4	-178.2	173.9	-110.6	0	0	0	111.4	L130 Q131 Y134 V164 N165 K166 T170 L171 L172	L130-Y168 HydrophobicContact CD2-CD2 4.17Å; L130-Y168 HydrophobicContact CD2-CE2 4.28Å; L130-Y168 HydrophobicContact CG-CD2 4.04Å; L130-Y168 HydrophobicContact CG-CE2 4.24Å; Q131-Y168 HydrophobicContact CB-CE2 4.26Å; Y134-Y168 HydrophobicContact CD1-CD1 4.01Å; Y134-Y168 HydrophobicContact CD1-CD2 4.27Å; Y134-Y168 HydrophobicContact CD1-CE1 4.05Å; Y134-Y168 HydrophobicContact CD1-CE2 4.3Å; Y134-Y168 HydrophobicContact CD1-CG 4.12Å; Y134-Y168 VanDerWaalsContact CD2-CB 3.47Å; Y134-Y168 AromaticContact CD2-CD1 3.92Å; Y134-Y168 HydrophobicContact CD2-CD1 3.92Å; Y134-Y168 HydrophobicContact CD2-CD2 4.16Å; Y134-Y168 AromaticContact CD2-CG 3.58Å; Y134-Y168 HydrophobicContact CD2-CG 3.58Å; Y134-Y168 HydrophobicContact CE1-CD1 4.11Å; Y134-Y168 HydrophobicContact CE1-CE1 4.16Å; Y134-Y168 AromaticContact CE2-CD1 4Å; Y134-Y168 HydrophobicContact CE2-CD1 4Å; Y134-Y168 HydrophobicContact CE2-CG 4.09Å; Y134-Y168 AromaticContact CG-CD1 3.92Å; Y134-Y168 HydrophobicContact CG-CD1 3.92Å; Y134-Y168 AromaticContact CG-CD2 3.74Å; Y134-Y168 HydrophobicContact CG-CD2 3.74Å; Y134-Y168 HydrophobicContact CG-CE1 4.35Å; Y134-Y168 HydrophobicContact CG-CE2 4.19Å; Y134-Y168 AromaticContact CG-CG 3.58Å; Y134-Y168 HydrophobicContact CG-CG 3.58Å; V164-Y168 VanDerWaalsContact O-CB 3.32Å; V164-Y168 WeakPolarHBondContact O-CB 3.19Å; V164-Y168 PolarHBondContact O-N 3.29Å; N165-Y168 PolarHBondContact O-N 3.03Å; K166-Y168 VanDerWaalsContact C-N 3.34Å; K166-Y168 PolarHBondContact O-N 3.35Å; Y168-T170 VanDerWaalsContact C-N 3.26Å; Y168-T170 PolarHBondContact O-N 3.25Å; Y168-L171 PolarHBondContact O-N 3.03Å; Y168-L172 HydrophobicContact CE1-CD2 4.05Å; Y168-L172 HydrophobicContact CE2-CD1 4.16Å; Y168-L172 WeakPolarHBondContact O-CB 3.39Å; Y168-L172 PolarHBondContact O-N 2.97Å
169	K	96.9	Very high	96	Very high	150 Å²	150	43.7 Å²	43.7	65%	0.652	23%	0.229	S	C	*	.	H	α-helix	trans	-59.4	-39	177.9	-72.6	178.1	-179.8	-177.5	0	112.2	N165 K166	N165-K169 WeakPolarHBondContact O-CB 3.45Å; N165-K169 WeakPolarHBondContact O-CG 3.36Å; N165-K169 PolarHBondContact O-N 2.91Å; K166-K169 PolarHBondContact O-N 3.26Å
170	T	96.9	Very high	96	Very high	26 Å²	26	42 Å²	42	16%	0.16	22%	0.215	C	C	.	.	H	α-helix	trans	-69.2	-49	-179.8	-54.4	0	0	0	0	111.2	Y113 K166 A167 Y168 L172 S176 R177 Y180	Y113-T170 HydrophobicContact CD2-CG2 3.91Å; Y113-T170 HydrophobicContact CE2-CG2 3.99Å; K166-T170 WeakPolarHBondContact O-CB 3.39Å; K166-T170 PolarHBondContact O-N 3.32Å; K166-T170 PolarHBondContact O-OG1 2.94Å; A167-T170 PolarHBondContact O-N 2.93Å; Y168-T170 VanDerWaalsContact C-N 3.26Å; Y168-T170 PolarHBondContact O-N 3.25Å; T170-L172 VanDerWaalsContact C-N 3.33Å; T170-L172 PolarHBondContact O-N 3.46Å; T170-S176 CarbonylContact O-C 3.57Å; T170-S176 WeakPolarHBondContact O-CB 3.26Å; T170-S176 PolarHBondContact O-OG 3.27Å; T170-R177 PolarHBondContact O-N 3.21Å; T170-R177 VanDerWaalsContact O-N 3.09Å; T170-Y180 HydrophobicContact CG2-CD1 4.44Å; T170-Y180 HydrophobicContact CG2-CD2 4.45Å; T170-Y180 HydrophobicContact CG2-CG 3.92Å
171	L	96.9	Very high	95.9	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-76.2	-17.9	-179.5	-62.2	-169.2	0	0	0	113.1	F114 L117 L125 L130 A167 Y168 R177 Y180	F114-L171 HydrophobicContact CD1-CD1 4.03Å; F114-L171 HydrophobicContact CD1-CD2 4.3Å; F114-L171 HydrophobicContact CD2-CD2 4.34Å; F114-L171 HydrophobicContact CE1-CD1 4.32Å; F114-L171 HydrophobicContact CE1-CD2 3.89Å; F114-L171 HydrophobicContact CE2-CD2 3.9Å; F114-L171 HydrophobicContact CG-CD1 4.31Å; F114-L171 HydrophobicContact CZ-CD2 3.66Å; L117-L171 HydrophobicContact CB-CD1 4.49Å; L117-L171 HydrophobicContact CD1-CD1 3.91Å; L117-L171 HydrophobicContact CD1-CG 4.45Å; L125-L171 HydrophobicContact CD1-CB 4.24Å; L125-L171 HydrophobicContact CD1-CD1 4.44Å; L130-L171 HydrophobicContact CD1-CB 4.31Å; L130-L171 HydrophobicContact CD1-CD1 4.26Å; L130-L171 HydrophobicContact CD2-CB 3.95Å; A167-L171 WeakPolarHBondContact O-CB 3.49Å; A167-L171 WeakPolarHBondContact O-CG 3.45Å; A167-L171 PolarHBondContact O-N 3.17Å; Y168-L171 PolarHBondContact O-N 3.03Å; L171-R177 HydrophobicContact CD2-CG 4.17Å; L171-R177 PolarHBondContact O-NE 3.05Å; L171-R177 PolarHBondContact O-NH2 2.87Å; L171-Y180 HydrophobicContact CD2-CD1 3.88Å; L171-Y180 HydrophobicContact CD2-CE1 4.28Å
172	L	95.8	Very high	95.7	Very high	59 Å²	59	41.7 Å²	41.7	31%	0.309	21%	0.213	S	C	.	.	H	α-helix	trans	-68.8	-45.7	-177.1	-178.9	66	0	0	0	112.7	T127 Y168 T170 R177	T127-L172 HydrophobicContact CG2-CD1 4.37Å; Y168-L172 HydrophobicContact CE1-CD2 4.05Å; Y168-L172 HydrophobicContact CE2-CD1 4.16Å; Y168-L172 WeakPolarHBondContact O-CB 3.39Å; Y168-L172 PolarHBondContact O-N 2.97Å; T170-L172 VanDerWaalsContact C-N 3.33Å; T170-L172 PolarHBondContact O-N 3.46Å; L172-R177 PolarHBondContact O-NH2 3.29Å
173	K	93.7	Very high	95.6	Very high	133 Å²	133	43.9 Å²	43.9	58%	0.578	21%	0.213	S	C	*	.	S	Bend	trans	-91.1	134.1	-177.4	-58	-174.9	176.3	-169.9	0	110.5	L175 S176 R177	K173-L175 VanDerWaalsContact C-N 3.34Å; K173-L175 PolarHBondContact O-N 3.23Å; K173-S176 WeakPolarHBondContact CB-OG 3.3Å; K173-S176 PolarHBondContact O-N 3.06Å; K173-S176 PolarHBondContact O-OG 2.88Å; K173-S176 VanDerWaalsContact O-OG 3.13Å; K173-R177 VanDerWaalsContact O-CB 3.31Å; K173-R177 WeakPolarHBondContact O-CB 3.45Å; K173-R177 PolarHBondContact O-N 2.98Å
174	P	94.3	Very high	95.4	Very high	51 Å²	51	45.5 Å²	45.5	33%	0.331	22%	0.222	S	C	.	.	H	α-helix	trans	-54.1	-46.3	-179.9	-27.6	34.8	0	0	0	113.2	F123 R177 G178 M258	F123-P174 WeakPolarHBondContact CE2-O 3.48Å; F123-P174 HydrophobicContact CZ-CB 3.94Å; P174-R177 WeakPolarHBondContact O-CB 3.43Å; P174-R177 PolarHBondContact O-N 3.3Å; P174-G178 PolarHBondContact O-N 3.43Å; P174-M258 HydrophobicContact CB-CE 4.43Å; P174-M258 HydrophobicContact CB-SD 4.17Å
175	L	93.6	Very high	95.1	Very high	37 Å²	37	50.5 Å²	50.5	19%	0.194	25%	0.245	C	C	.	.	H	α-helix	trans	-57.4	-56.2	179.4	-179.7	62.4	0	0	0	111.9	K173 R177 G178 L179 L255 M258 K259 A262	K173-L175 VanDerWaalsContact C-N 3.34Å; K173-L175 PolarHBondContact O-N 3.23Å; L175-R177 VanDerWaalsContact C-N 3.27Å; L175-R177 PolarHBondContact O-N 3.47Å; L175-G178 PolarHBondContact O-N 3.19Å; L175-L179 HydrophobicContact CD1-CG 4.48Å; L175-L179 HydrophobicContact CG-CD1 4.46Å; L175-L179 VanDerWaalsContact O-CG 3.3Å; L175-L179 WeakPolarHBondContact O-CG 3.48Å; L175-L179 PolarHBondContact O-N 2.95Å; L175-L255 HydrophobicContact CD1-CD2 4.21Å; L175-M258 HydrophobicContact CB-CG 4.44Å; L175-M258 HydrophobicContact CB-SD 4.15Å; L175-M258 HydrophobicContact CD1-CB 4.34Å; L175-M258 HydrophobicContact CD1-CG 4.19Å; L175-M258 HydrophobicContact CD1-SD 4.4Å; L175-K259 HydrophobicContact CD1-CB 4.14Å; L175-K259 HydrophobicContact CD2-CB 4.22Å; L175-K259 HydrophobicContact CD2-CG 4.27Å; L175-A262 HydrophobicContact CD2-CB 4.22Å
176	S	94.8	Very high	94.8	Very high	33 Å²	33	51 Å²	51	23%	0.231	26%	0.262	C	S	.	.	H	α-helix	trans	-65	-31.6	-179.2	53	0	0	0	0	112.9	T170 K173 Y180	T170-S176 CarbonylContact O-C 3.57Å; T170-S176 WeakPolarHBondContact O-CB 3.26Å; T170-S176 PolarHBondContact O-OG 3.27Å; K173-S176 WeakPolarHBondContact CB-OG 3.3Å; K173-S176 PolarHBondContact O-N 3.06Å; K173-S176 PolarHBondContact O-OG 2.88Å; K173-S176 VanDerWaalsContact O-OG 3.13Å; S176-Y180 VanDerWaalsContact O-CB 3.31Å; S176-Y180 WeakPolarHBondContact O-CB 3.18Å; S176-Y180 PolarHBondContact O-N 3.38Å
177	R	96.3	Very high	94.2	Very high	9 Å²	9	46.9 Å²	46.9	3%	0.034	25%	0.245	C	C	.	.	H	α-helix	trans	-63.2	-49	174.5	-177	-169.6	-56.7	161.3	1.5	110.9	F114 F123 T170 L171 L172 K173 P174 L175 Y180 M181	F114-R177 HydrophobicContact CZ-CG 4.31Å; F123-R177 HydrophobicContact CD2-CG 4.42Å; F123-R177 WeakPolarHBondContact O-CD 3.34Å; F123-R177 PolarHBondContact O-NH1 3.05Å; T170-R177 PolarHBondContact O-N 3.21Å; T170-R177 VanDerWaalsContact O-N 3.09Å; L171-R177 HydrophobicContact CD2-CG 4.17Å; L171-R177 PolarHBondContact O-NE 3.05Å; L171-R177 PolarHBondContact O-NH2 2.87Å; L172-R177 PolarHBondContact O-NH2 3.29Å; K173-R177 VanDerWaalsContact O-CB 3.31Å; K173-R177 WeakPolarHBondContact O-CB 3.45Å; K173-R177 PolarHBondContact O-N 2.98Å; P174-R177 WeakPolarHBondContact O-CB 3.43Å; P174-R177 PolarHBondContact O-N 3.3Å; L175-R177 VanDerWaalsContact C-N 3.27Å; L175-R177 PolarHBondContact O-N 3.47Å; R177-Y180 WeakPolarHBondContact O-CB 3.35Å; R177-Y180 PolarHBondContact O-N 2.98Å; R177-M181 HydrophobicContact CG-SD 4.33Å; R177-M181 WeakPolarHBondContact O-CG 3.19Å; R177-M181 PolarHBondContact O-N 2.94Å
178	G	94.6	Very high	93.3	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-63.8	-43.7	179.3	0	0	0	0	0	112.5	P174 L175 Y180 M181 L182	P174-G178 PolarHBondContact O-N 3.43Å; L175-G178 PolarHBondContact O-N 3.19Å; G178-Y180 VanDerWaalsContact C-N 3.27Å; G178-Y180 PolarHBondContact O-N 3.44Å; G178-M181 PolarHBondContact O-N 3.26Å; G178-M181 VanDerWaalsContact O-N 3.16Å; G178-L182 WeakPolarHBondContact O-CG 3.33Å; G178-L182 PolarHBondContact O-N 3.09Å
179	L	93.6	Very high	92.1	Very high	59 Å²	59	53.2 Å²	53.2	31%	0.309	28%	0.276	S	S	.	.	H	α-helix	trans	-57.9	-42.4	174.5	-63.3	-176.3	0	0	0	112.2	L175 L182 E183 L189 L255	L175-L179 HydrophobicContact CD1-CG 4.48Å; L175-L179 HydrophobicContact CG-CD1 4.46Å; L175-L179 VanDerWaalsContact O-CG 3.3Å; L175-L179 WeakPolarHBondContact O-CG 3.48Å; L175-L179 PolarHBondContact O-N 2.95Å; L179-L182 PolarHBondContact O-N 3.41Å; L179-E183 PolarHBondContact O-N 3.37Å; L179-L189 HydrophobicContact CD2-CD1 3.1Å; L179-L189 HydrophobicContact CD2-CG 3.65Å; L179-L189 HydrophobicContact CG-CD1 4.47Å; L179-L255 HydrophobicContact CD2-CB 4.39Å; L179-L255 HydrophobicContact CD2-CD1 4.45Å
180	Y	95.6	Very high	90.4	Very high	17 Å²	17	53 Å²	53	7%	0.067	28%	0.275	C	S	.	.	H	α-helix	trans	-66.6	-38.9	177.3	176.5	-113.9	0	0	0	112.6	S112 Y113 F114 T170 L171 S176 R177 G178 E183 L184	S112-Y180 WeakPolarHBondContact CA-OH 3.5Å; Y113-Y180 AromaticContact CD2-CD1 3.95Å; Y113-Y180 HydrophobicContact CD2-CD1 3.95Å; Y113-Y180 AromaticContact CD2-CD2 3.93Å; Y113-Y180 HydrophobicContact CD2-CD2 3.93Å; Y113-Y180 AromaticContact CD2-CE1 3.67Å; Y113-Y180 HydrophobicContact CD2-CE1 3.67Å; Y113-Y180 AromaticContact CD2-CE2 3.66Å; Y113-Y180 HydrophobicContact CD2-CE2 3.66Å; Y113-Y180 HydrophobicContact CD2-CG 4.07Å; Y113-Y180 AromaticContact CD2-CZ 3.52Å; Y113-Y180 AromaticContact CE2-CD2 3.97Å; Y113-Y180 HydrophobicContact CE2-CD2 3.97Å; Y113-Y180 AromaticContact CE2-CE2 3.77Å; Y113-Y180 HydrophobicContact CE2-CE2 3.77Å; Y113-Y180 HydrophobicContact CE2-CG 4.46Å; Y113-Y180 AromaticContact CG-CE1 3.8Å; Y113-Y180 HydrophobicContact CG-CE1 3.8Å; Y113-Y180 HydrophobicContact CG-CE2 4.15Å; Y113-Y180 AromaticContact CG-CZ 3.61Å; Y113-Y180 PolarHBondContact N-OH 3.37Å; F114-Y180 HydrophobicContact CD2-CD1 4.37Å; F114-Y180 AromaticContact CD2-CE1 3.85Å; F114-Y180 HydrophobicContact CD2-CE1 3.85Å; F114-Y180 AromaticContact CE2-CD1 3.79Å; F114-Y180 HydrophobicContact CE2-CD1 3.79Å; F114-Y180 AromaticContact CE2-CE1 3.73Å; F114-Y180 HydrophobicContact CE2-CE1 3.73Å; T170-Y180 HydrophobicContact CG2-CD1 4.44Å; T170-Y180 HydrophobicContact CG2-CD2 4.45Å; T170-Y180 HydrophobicContact CG2-CG 3.92Å; L171-Y180 HydrophobicContact CD2-CD1 3.88Å; L171-Y180 HydrophobicContact CD2-CE1 4.28Å; S176-Y180 VanDerWaalsContact O-CB 3.31Å; S176-Y180 WeakPolarHBondContact O-CB 3.18Å; S176-Y180 PolarHBondContact O-N 3.38Å; R177-Y180 WeakPolarHBondContact O-CB 3.35Å; R177-Y180 PolarHBondContact O-N 2.98Å; G178-Y180 VanDerWaalsContact C-N 3.27Å; G178-Y180 PolarHBondContact O-N 3.44Å; Y180-E183 WeakPolarHBondContact O-CB 3.44Å; Y180-E183 PolarHBondContact O-N 3.11Å; Y180-L184 HydrophobicContact CD1-CD1 4.15Å; Y180-L184 HydrophobicContact CE1-CD1 3.55Å; Y180-L184 HydrophobicContact CE1-CG 4.19Å; Y180-L184 HydrophobicContact CE2-CD1 4.36Å; Y180-L184 HydrophobicContact CE2-CD2 4.19Å; Y180-L184 HydrophobicContact CE2-CG 4.1Å; Y180-L184 WeakPolarHBondContact O-CG 3.45Å; Y180-L184 PolarHBondContact O-N 3.46Å
181	M	95.1	Very high	88.5	Confident	5 Å²	5	60 Å²	60	3%	0.025	31%	0.306	C	S	.	.	H	α-helix	trans	-62.6	-42.3	174.3	-70.2	175.9	76.1	0	0	111.5	F114 Y121 F123 R177 G178 E183 L184 E185 L243	F114-M181 HydrophobicContact CE2-CG 3.77Å; F114-M181 HydrophobicContact CZ-CG 3.59Å; F114-M181 HydrophobicContact CZ-SD 3.86Å; Y121-M181 HydrophobicContact CD1-CE 4.39Å; Y121-M181 HydrophobicContact CE1-CE 3.93Å; Y121-M181 HydrophobicContact CE2-CE 4.3Å; Y121-M181 HydrophobicContact CE2-CG 4.26Å; F123-M181 HydrophobicContact CB-CE 4.3Å; F123-M181 HydrophobicContact CB-SD 3.88Å; F123-M181 HydrophobicContact CD2-SD 4.06Å; F123-M181 HydrophobicContact CG-SD 4.5Å; R177-M181 HydrophobicContact CG-SD 4.33Å; R177-M181 WeakPolarHBondContact O-CG 3.19Å; R177-M181 PolarHBondContact O-N 2.94Å; G178-M181 PolarHBondContact O-N 3.26Å; G178-M181 VanDerWaalsContact O-N 3.16Å; M181-E183 VanDerWaalsContact C-N 3.34Å; M181-E183 PolarHBondContact O-N 3.3Å; M181-L184 WeakPolarHBondContact O-CB 3.16Å; M181-L184 PolarHBondContact O-N 3.29Å; M181-E185 PolarHBondContact O-N 3.13Å; M181-L243 HydrophobicContact CE-CD1 4.04Å; M181-L243 HydrophobicContact SD-CD1 4.07Å
182	L	93.1	Very high	86.3	Confident	3 Å²	3	64.1 Å²	64.1	2%	0.016	35%	0.348	C	S	.	.	H	α-helix	trans	-63.3	-39.6	174.2	-65.4	-168.3	0	0	0	112.5	G178 L179 L184 E185 G186 M187 L243 L248 A251 K252 L255	G178-L182 WeakPolarHBondContact O-CG 3.33Å; G178-L182 PolarHBondContact O-N 3.09Å; L179-L182 PolarHBondContact O-N 3.41Å; L182-L184 VanDerWaalsContact C-N 3.29Å; L182-L184 PolarHBondContact O-N 3.11Å; L182-E185 CarbonylContact O-C 3.59Å; L182-E185 WeakPolarHBondContact O-CA 3.46Å; L182-E185 PolarHBondContact O-N 2.82Å; L182-E185 VanDerWaalsContact O-N 3.07Å; L182-G186 PolarHBondContact O-N 3.29Å; L182-M187 CarbonylContact C-O 3.49Å; L182-M187 HydrophobicContact CB-CB 4.28Å; L182-M187 HydrophobicContact CB-CE 4.35Å; L182-M187 HydrophobicContact CD1-CE 4.08Å; L182-M187 HydrophobicContact CD2-CE 3.58Å; L182-M187 HydrophobicContact CG-CE 4.21Å; L182-M187 PolarHBondContact O-N 2.74Å; L182-M187 VanDerWaalsContact O-O 3.11Å; L182-L243 HydrophobicContact CD2-CD2 3.74Å; L182-L248 HydrophobicContact CD2-CD2 4.19Å; L182-A251 HydrophobicContact CD2-CB 4.17Å; L182-K252 HydrophobicContact CD1-CB 4.06Å; L182-K252 HydrophobicContact CD1-CG 4.24Å; L182-L255 HydrophobicContact CD1-CD1 3.54Å; L182-L255 HydrophobicContact CG-CD1 3.83Å
183	E	93.1	Very high	84	Confident	103 Å²	103	65.3 Å²	65.3	48%	0.481	36%	0.359	S	S	.	.	H	α-helix	trans	-61	-39.1	176.2	173.9	174.3	-160.5	0	0	111.7	L179 Y180 M181 E185 G186 M187	L179-E183 PolarHBondContact O-N 3.37Å; Y180-E183 WeakPolarHBondContact O-CB 3.44Å; Y180-E183 PolarHBondContact O-N 3.11Å; M181-E183 VanDerWaalsContact C-N 3.34Å; M181-E183 PolarHBondContact O-N 3.3Å; E183-E185 PolarHBondContact O-N 3.44Å; E183-G186 PolarHBondContact O-N 2.63Å; E183-M187 WeakPolarHBondContact CA-O 3.21Å; E183-M187 PolarHBondContact N-O 3.15Å
184	L	93.3	Very high	82	Confident	70 Å²	70	61.5 Å²	61.5	37%	0.366	34%	0.344	S	S	.	.	H	α-helix	trans	-63.6	-29.1	174.8	-71.1	174.2	0	0	0	112.8	F114 Y121 Y180 M181 L182 G186	F114-L184 HydrophobicContact CD2-CD1 4.22Å; F114-L184 HydrophobicContact CE2-CD1 4.18Å; Y121-L184 HydrophobicContact CE2-CD1 3.71Å; Y180-L184 HydrophobicContact CD1-CD1 4.15Å; Y180-L184 HydrophobicContact CE1-CD1 3.55Å; Y180-L184 HydrophobicContact CE1-CG 4.19Å; Y180-L184 HydrophobicContact CE2-CD1 4.36Å; Y180-L184 HydrophobicContact CE2-CD2 4.19Å; Y180-L184 HydrophobicContact CE2-CG 4.1Å; Y180-L184 WeakPolarHBondContact O-CG 3.45Å; Y180-L184 PolarHBondContact O-N 3.46Å; M181-L184 WeakPolarHBondContact O-CB 3.16Å; M181-L184 PolarHBondContact O-N 3.29Å; L182-L184 VanDerWaalsContact C-N 3.29Å; L182-L184 PolarHBondContact O-N 3.11Å; L184-G186 VanDerWaalsContact C-N 3.25Å; L184-G186 PolarHBondContact O-N 3.04Å
185	E	91.1	Very high	79.9	Confident	106 Å²	106	64.2 Å²	64.2	50%	0.495	36%	0.364	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.8	5.1	173.3	-60.4	-58.9	142	0	0	113	Y121 M181 L182 E183 M187 L248	Y121-E185 PolarHBondContact OH-OE1 3.04Å; M181-E185 PolarHBondContact O-N 3.13Å; L182-E185 CarbonylContact O-C 3.59Å; L182-E185 WeakPolarHBondContact O-CA 3.46Å; L182-E185 PolarHBondContact O-N 2.82Å; L182-E185 VanDerWaalsContact O-N 3.07Å; E183-E185 PolarHBondContact O-N 3.44Å; E185-M187 VanDerWaalsContact C-N 3.33Å; E185-L248 HydrophobicContact CB-CD1 3.82Å; E185-L248 HydrophobicContact CB-CD2 4.35Å; E185-L248 HydrophobicContact CG-CD1 4.28Å; E185-L248 HydrophobicContact CG-CD2 4.1Å
186	G	89.7	Confident	78	Confident	58 Å²	58	68 Å²	68	60%	0.598	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	79.2	13	179.3	0	0	0	0	0	114.4	L182 E183 L184	L182-G186 PolarHBondContact O-N 3.29Å; E183-G186 PolarHBondContact O-N 2.63Å; L184-G186 VanDerWaalsContact C-N 3.25Å; L184-G186 PolarHBondContact O-N 3.04Å
187	M	85.4	Confident	76.3	Confident	36 Å²	36	67.9 Å²	67.9	18%	0.177	39%	0.39	C	S	.	.			trans	-102.4	134.1	175.6	-68.5	-153.8	-48.7	0	0	112.1	L182 E183 E185 L248 K252	L182-M187 CarbonylContact C-O 3.49Å; L182-M187 HydrophobicContact CB-CB 4.28Å; L182-M187 HydrophobicContact CB-CE 4.35Å; L182-M187 HydrophobicContact CD1-CE 4.08Å; L182-M187 HydrophobicContact CD2-CE 3.58Å; L182-M187 HydrophobicContact CG-CE 4.21Å; L182-M187 PolarHBondContact O-N 2.74Å; L182-M187 VanDerWaalsContact O-O 3.11Å; E183-M187 WeakPolarHBondContact CA-O 3.21Å; E183-M187 PolarHBondContact N-O 3.15Å; E185-M187 VanDerWaalsContact C-N 3.33Å; M187-L248 HydrophobicContact CE-CB 3.39Å; M187-L248 HydrophobicContact CE-CD1 4.18Å; M187-L248 HydrophobicContact CE-CD2 4.3Å; M187-L248 HydrophobicContact CE-CG 4.14Å; M187-L248 WeakPolarHBondContact CE-O 3.21Å; M187-L248 HydrophobicContact SD-CB 3.81Å; M187-L248 HydrophobicContact SD-CD1 4.33Å; M187-K252 HydrophobicContact CE-CB 4.46Å
188	H	78.3	Confident	75.3	Confident	121 Å²	121	72 Å²	72	56%	0.56	41%	0.413	S	S	*	.			trans	-119.1	135.9	175.9	-61	-74.4	0	0	0	110.7	K190	H188-K190 PolarHBondContact O-N 2.81Å
189	L	72	Confident	74.8	Confident	42 Å²	42	76.7 Å²	76.7	22%	0.22	45%	0.445	C	S	.	.	P	Polyproline II helix	trans	-70.2	118	160.8	-68	-165.4	0	0	0	108.1	L179 K252	L179-L189 HydrophobicContact CD2-CD1 3.1Å; L179-L189 HydrophobicContact CD2-CG 3.65Å; L179-L189 HydrophobicContact CG-CD1 4.47Å; L189-K252 HydrophobicContact CD2-CB 4.42Å; L189-K252 HydrophobicContact CD2-CD 3.91Å; L189-K252 HydrophobicContact CD2-CG 3.17Å
190	K	62.3	Low	74.5	Confident	146 Å²	146	79.3 Å²	79.3	64%	0.635	46%	0.456	S	S	*	.	P	Polyproline II helix	trans	-83	121.2	171.2	-73.1	-177.2	179.7	174.8	0	108.2	H188 G192 T193	H188-K190 PolarHBondContact O-N 2.81Å; K190-G192 PolarHBondContact O-N 3.2Å; K190-G192 VanDerWaalsContact O-N 3.16Å; K190-T193 VanDerWaalsContact CB-OG1 3.22Å; K190-T193 WeakPolarHBondContact CB-OG1 3.48Å
191	E	56.3	Low	74.2	Confident	172 Å²	172	79 Å²	79	80%	0.804	46%	0.455	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.7	121	172.3	-68.5	-171.1	144.9	0	0	110
192	G	50.8	Low	73.9	Confident	86 Å²	86	82.5 Å²	82.5	89%	0.887	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	88.4	7.1	171.7	0	0	0	0	0	116.9	K190	K190-G192 PolarHBondContact O-N 3.2Å; K190-G192 VanDerWaalsContact O-N 3.16Å
193	T	46.7	Very low	73.8	Confident	85 Å²	85	87 Å²	87	52%	0.521	50%	0.495	S	S	.	.	T	Hydrogen-bonded Turn	trans	-123.1	-4.1	176.5	18.9	0	0	0	0	115.9	K190 S195	K190-T193 VanDerWaalsContact CB-OG1 3.22Å; K190-T193 WeakPolarHBondContact CB-OG1 3.48Å; T193-S195 PolarHBondContact O-N 3.09Å; T193-S195 PolarHBondContact O-OG 2.88Å
194	D	51.5	Low	73.8	Confident	52 Å²	52	83.9 Å²	83.9	28%	0.278	48%	0.481	S	S	.	.			trans	-78.9	74.5	177.8	-66.1	-34.8	0	0	0	110.2	V196 K252	D194-V196 VanDerWaalsContact C-N 3.28Å; D194-V196 PolarHBondContact O-N 2.87Å; D194-K252 WeakPolarHBondContact OD1-CE 3.34Å; D194-K252 IonicContact OD1-NZ 2.74Å; D194-K252 PolarHBondContact OD1-NZ 2.93Å; D194-K252 IonicContact OD2-NZ 3.78Å
195	S	51.6	Low	73.7	Confident	108 Å²	108	81.7 Å²	81.7	76%	0.755	47%	0.469	S	S	*	.			trans	-85.4	58.9	179.7	41.5	0	0	0	0	110.5	T193	T193-S195 PolarHBondContact O-N 3.09Å; T193-S195 PolarHBondContact O-OG 2.88Å
196	V	53.4	Low	73.8	Confident	118 Å²	118	83.1 Å²	83.1	72%	0.715	48%	0.478	S	S	*	.			trans	-150.5	54.7	160.2	-161.6	0	0	0	0	109	D194 D198	D194-V196 VanDerWaalsContact C-N 3.28Å; D194-V196 PolarHBondContact O-N 2.87Å; V196-D198 PolarHBondContact O-N 2.94Å
197	A	59.4	Low	74.1	Confident	30 Å²	30	85.6 Å²	85.6	25%	0.248	47%	0.473	C	S	.	.			trans	-71.7	109.8	155.8	0	0	0	0	0	105.5	S199 F201 L202	A197-S199 PolarHBondContact O-N 2.68Å; A197-F201 HydrophobicContact CB-CD1 4.06Å; A197-L202 HydrophobicContact CB-CD1 4.03Å; A197-L202 HydrophobicContact CB-CD2 3.49Å; A197-L202 VanDerWaalsContact CB-CD2 3.49Å; A197-L202 HydrophobicContact CB-CG 3.58Å
198	D	75.2	Confident	74.6	Confident	96 Å²	96	84.7 Å²	84.7	51%	0.513	47%	0.469	S	S	.	.			trans	-47.2	140.1	175.8	177.3	33.2	0	0	0	110	V196 H200 F201 L202	V196-D198 PolarHBondContact O-N 2.94Å; D198-H200 PolarHBondContact O-N 3.19Å; D198-H200 VanDerWaalsContact O-N 3.12Å; D198-H200 WeakPolarHBondContact OD2-CB 3.14Å; D198-F201 HydrophobicContact CB-CB 4.31Å; D198-F201 WeakPolarHBondContact O-CA 3.41Å; D198-F201 WeakPolarHBondContact O-CB 3.1Å; D198-F201 PolarHBondContact O-N 3.09Å; D198-L202 PolarHBondContact O-N 3.34Å
199	S	83.8	Confident	75.4	Confident	97 Å²	97	80.4 Å²	80.4	68%	0.678	45%	0.45	S	S	*	.	H	α-helix	trans	-56.8	-34.4	-175.1	-176	0	0	0	0	111.4	A197 M203	A197-S199 PolarHBondContact O-N 2.68Å; S199-M203 PolarHBondContact O-N 2.66Å
200	H	87	Confident	76.5	Confident	115 Å²	115	83.9 Å²	83.9	53%	0.532	47%	0.465	S	S	.	.	H	α-helix	trans	-64.3	-45.8	175.6	-177.2	-83.5	0	0	0	111.6	D198 L202 M203 E204	D198-H200 PolarHBondContact O-N 3.19Å; D198-H200 VanDerWaalsContact O-N 3.12Å; D198-H200 WeakPolarHBondContact OD2-CB 3.14Å; H200-L202 PolarHBondContact O-N 3.28Å; H200-M203 PolarHBondContact O-N 3.41Å; H200-E204 PolarHBondContact O-N 2.83Å
201	F	89.1	Confident	78.2	Confident	10 Å²	10	79 Å²	79	4%	0.044	45%	0.452	C	S	.	.	H	α-helix	trans	-62.7	-40.6	178.7	176.8	-106.9	0	0	0	112.7	A197 D198 E204 L205 Q257 Y260 Y261	A197-F201 HydrophobicContact CB-CD1 4.06Å; D198-F201 HydrophobicContact CB-CB 4.31Å; D198-F201 WeakPolarHBondContact O-CA 3.41Å; D198-F201 WeakPolarHBondContact O-CB 3.1Å; D198-F201 PolarHBondContact O-N 3.09Å; F201-E204 PolarHBondContact O-N 3.32Å; F201-L205 WeakPolarHBondContact O-CB 3.2Å; F201-L205 PolarHBondContact O-N 2.97Å; F201-Q257 HydrophobicContact CD1-CG 4.29Å; F201-Q257 HydrophobicContact CD2-CG 4.12Å; F201-Q257 HydrophobicContact CE1-CB 4.44Å; F201-Q257 HydrophobicContact CE1-CG 4.1Å; F201-Q257 HydrophobicContact CE2-CB 3.89Å; F201-Q257 HydrophobicContact CE2-CG 3.91Å; F201-Q257 HydrophobicContact CG-CG 4.29Å; F201-Q257 HydrophobicContact CZ-CB 3.82Å; F201-Q257 HydrophobicContact CZ-CG 3.9Å; F201-Y260 AromaticContact CE1-CD2 3.71Å; F201-Y260 HydrophobicContact CE1-CD2 3.71Å; F201-Y260 HydrophobicContact CE1-CE2 4.33Å; F201-Y260 HydrophobicContact CE1-CG 4.16Å; F201-Y260 HydrophobicContact CZ-CD2 4.03Å; F201-Y260 HydrophobicContact CZ-CG 4.24Å; F201-Y261 HydrophobicContact CD2-CE2 4.43Å; F201-Y261 HydrophobicContact CE2-CD2 4.25Å; F201-Y261 AromaticContact CE2-CE2 3.51Å; F201-Y261 HydrophobicContact CE2-CE2 3.51Å; F201-Y261 AromaticContact CE2-CZ 3.73Å; F201-Y261 HydrophobicContact CZ-CE2 4.32Å
202	L	88.9	Confident	80	Confident	78 Å²	78	71.2 Å²	71.2	41%	0.408	42%	0.416	S	S	.	.	H	α-helix	trans	-63.9	-41.6	176.3	-71.7	177.3	0	0	0	112.2	A197 D198 H200 L205 M206	A197-L202 HydrophobicContact CB-CD1 4.03Å; A197-L202 HydrophobicContact CB-CD2 3.49Å; A197-L202 VanDerWaalsContact CB-CD2 3.49Å; A197-L202 HydrophobicContact CB-CG 3.58Å; D198-L202 PolarHBondContact O-N 3.34Å; H200-L202 PolarHBondContact O-N 3.28Å; L202-L205 PolarHBondContact O-N 2.77Å; L202-M206 WeakPolarHBondContact O-CG 3.31Å; L202-M206 PolarHBondContact O-N 3.13Å
203	M	91.1	Very high	82.1	Confident	98 Å²	98	74 Å²	74	48%	0.483	41%	0.406	S	S	.	.	H	α-helix	trans	-62.5	-47.1	176.6	-175.1	173	69.2	0	0	110.9	S199 H200 L205 M206 E207	S199-M203 PolarHBondContact O-N 2.66Å; H200-M203 PolarHBondContact O-N 3.41Å; M203-L205 VanDerWaalsContact C-N 3.3Å; M203-L205 PolarHBondContact O-N 3.34Å; M203-M206 WeakPolarHBondContact O-CB 3.28Å; M203-M206 PolarHBondContact O-N 2.68Å; M203-E207 WeakPolarHBondContact O-CG 3.31Å; M203-E207 PolarHBondContact O-N 2.79Å
204	E	92.2	Very high	84.5	Confident	37 Å²	37	76 Å²	76	17%	0.173	41%	0.409	C	S	.	.	H	α-helix	trans	-58.5	-41.8	175.7	-171.4	-170.7	157.3	0	0	112	H200 F201 M206 E207 I208 K231 Y261	H200-E204 PolarHBondContact O-N 2.83Å; F201-E204 PolarHBondContact O-N 3.32Å; E204-M206 VanDerWaalsContact C-N 3.32Å; E204-M206 PolarHBondContact O-N 3.29Å; E204-E207 PolarHBondContact O-N 3.44Å; E204-I208 HydrophobicContact CG-CD1 4.14Å; E204-I208 WeakPolarHBondContact O-CD1 3.35Å; E204-I208 VanDerWaalsContact O-CG1 3.24Å; E204-I208 WeakPolarHBondContact O-CG1 3.48Å; E204-I208 PolarHBondContact O-N 3.03Å; E204-K231 WeakPolarHBondContact OE1-CD 3.07Å; E204-K231 WeakPolarHBondContact OE1-CE 3.41Å; E204-K231 IonicContact OE1-NZ 2.63Å; E204-K231 PolarHBondContact OE1-NZ 3.35Å; E204-Y261 PolarHBondContact OE1-OH 3.39Å; E204-Y261 PolarHBondContact OE2-OH 3.41Å
205	L	92.6	Very high	86.6	Confident	24 Å²	24	73.7 Å²	73.7	13%	0.126	40%	0.398	C	S	.	.	H	α-helix	trans	-62.7	-39.7	175.4	179.7	61.5	0	0	0	111.7	F201 L202 M203 N209 Y260 I264	F201-L205 WeakPolarHBondContact O-CB 3.2Å; F201-L205 PolarHBondContact O-N 2.97Å; L202-L205 PolarHBondContact O-N 2.77Å; M203-L205 VanDerWaalsContact C-N 3.3Å; M203-L205 PolarHBondContact O-N 3.34Å; L205-N209 PolarHBondContact O-N 2.77Å; L205-N209 VanDerWaalsContact O-N 3.11Å; L205-N209 PolarHBondContact O-ND2 2.85Å; L205-Y260 HydrophobicContact CD2-CD1 3.5Å; L205-Y260 HydrophobicContact CD2-CE1 4.08Å; L205-Y260 HydrophobicContact CD2-CG 3.99Å; L205-I264 HydrophobicContact CD1-CD1 3.31Å; L205-I264 HydrophobicContact CD1-CG1 3.85Å
206	M	92.6	Very high	88.6	Confident	137 Å²	137	75.3 Å²	75.3	68%	0.675	39%	0.394	S	S	*	.	H	α-helix	trans	-63.8	-48.5	175.7	-71	175.9	61.8	0	0	111.2	L202 M203 E204 I208 N209 E210	L202-M206 WeakPolarHBondContact O-CG 3.31Å; L202-M206 PolarHBondContact O-N 3.13Å; M203-M206 WeakPolarHBondContact O-CB 3.28Å; M203-M206 PolarHBondContact O-N 2.68Å; E204-M206 VanDerWaalsContact C-N 3.32Å; E204-M206 PolarHBondContact O-N 3.29Å; M206-I208 VanDerWaalsContact C-N 3.32Å; M206-I208 PolarHBondContact O-N 2.88Å; M206-N209 PolarHBondContact O-N 3.33Å; M206-N209 VanDerWaalsContact O-N 3.11Å; M206-E210 PolarHBondContact O-N 2.98Å
207	E	95.3	Very high	90.6	Very high	109 Å²	109	72 Å²	72	51%	0.509	37%	0.374	S	S	.	.	H	α-helix	trans	-57	-43.4	178	-70.6	173.1	-172.2	0	0	111.9	M203 E204 E210 A211	M203-E207 WeakPolarHBondContact O-CG 3.31Å; M203-E207 PolarHBondContact O-N 2.79Å; E204-E207 PolarHBondContact O-N 3.44Å; E207-E210 PolarHBondContact O-N 3.34Å; E207-A211 VanDerWaalsContact O-CB 3.31Å; E207-A211 WeakPolarHBondContact O-CB 3.44Å; E207-A211 PolarHBondContact O-N 3.38Å
208	I	95.8	Very high	92.3	Very high	18 Å²	18	72.9 Å²	72.9	9%	0.092	38%	0.377	C	S	.	.	H	α-helix	trans	-65.5	-40.3	177.7	-65.4	164	0	0	0	111.4	E204 M206 L212 I224 Y261 I264	E204-I208 HydrophobicContact CG-CD1 4.14Å; E204-I208 WeakPolarHBondContact O-CD1 3.35Å; E204-I208 VanDerWaalsContact O-CG1 3.24Å; E204-I208 WeakPolarHBondContact O-CG1 3.48Å; E204-I208 PolarHBondContact O-N 3.03Å; M206-I208 VanDerWaalsContact C-N 3.32Å; M206-I208 PolarHBondContact O-N 2.88Å; I208-L212 VanDerWaalsContact O-CB 3.23Å; I208-L212 WeakPolarHBondContact O-CB 3.37Å; I208-L212 PolarHBondContact O-N 3.47Å; I208-I224 HydrophobicContact CG2-CG2 4.06Å; I208-Y261 HydrophobicContact CD1-CD1 4.4Å; I208-Y261 HydrophobicContact CD1-CE1 3.75Å; I208-I264 HydrophobicContact CB-CD1 4.22Å; I208-I264 HydrophobicContact CD1-CD1 4.12Å; I208-I264 HydrophobicContact CG2-CD1 3.73Å; I208-I264 HydrophobicContact CG2-CG1 4.33Å; I208-I264 HydrophobicContact CG2-CG2 3.69Å
209	N	95.6	Very high	93.3	Very high	30 Å²	30	74.5 Å²	74.5	16%	0.16	38%	0.382	C	S	.	.	H	α-helix	trans	-68	-42.1	178.3	-77.4	-71.6	0	0	0	111.5	L205 M206 L212 E213 K267	L205-N209 PolarHBondContact O-N 2.77Å; L205-N209 VanDerWaalsContact O-N 3.11Å; L205-N209 PolarHBondContact O-ND2 2.85Å; M206-N209 PolarHBondContact O-N 3.33Å; M206-N209 VanDerWaalsContact O-N 3.11Å; N209-L212 PolarHBondContact O-N 3.46Å; N209-E213 WeakPolarHBondContact O-CG 3.48Å; N209-E213 PolarHBondContact O-N 3.16Å; N209-K267 PolarHBondContact OD1-NZ 3.23Å
210	E	96.3	Very high	93.9	Very high	115 Å²	115	74.2 Å²	74.2	54%	0.537	37%	0.369	S	S	.	.	H	α-helix	trans	-61.7	-50.2	175.9	-176	170.2	-155.4	0	0	110.8	M206 E207 L212 E213 E214	M206-E210 PolarHBondContact O-N 2.98Å; E207-E210 PolarHBondContact O-N 3.34Å; E210-L212 PolarHBondContact O-N 3.21Å; E210-E213 PolarHBondContact O-N 2.64Å; E210-E214 HydrophobicContact CG-CG 4.46Å; E210-E214 WeakPolarHBondContact O-CG 3.47Å; E210-E214 PolarHBondContact O-N 2.91Å
211	A	96.3	Very high	94.3	Very high	43 Å²	43	68.8 Å²	68.8	36%	0.355	34%	0.344	S	S	.	.	H	α-helix	trans	-57.9	-38.4	175.2	0	0	0	0	0	112.2	E207 A215 I224	E207-A211 VanDerWaalsContact O-CB 3.31Å; E207-A211 WeakPolarHBondContact O-CB 3.44Å; E207-A211 PolarHBondContact O-N 3.38Å; A211-A215 WeakPolarHBondContact O-CB 3.44Å; A211-A215 PolarHBondContact O-N 3.1Å; A211-I224 HydrophobicContact CB-CD1 4.05Å; A211-I224 WeakPolarHBondContact O-CD1 3.49Å
212	L	95.9	Very high	94.6	Very high	9 Å²	9	71.9 Å²	71.9	5%	0.047	36%	0.361	C	S	.	.	H	α-helix	trans	-68.2	-36.5	176.3	-175.9	62.1	0	0	0	111.8	I208 N209 E210 V221 I224 K267 V268 K271	I208-L212 VanDerWaalsContact O-CB 3.23Å; I208-L212 WeakPolarHBondContact O-CB 3.37Å; I208-L212 PolarHBondContact O-N 3.47Å; N209-L212 PolarHBondContact O-N 3.46Å; E210-L212 PolarHBondContact O-N 3.21Å; L212-V221 HydrophobicContact CD1-CG1 3.93Å; L212-V221 HydrophobicContact CD1-CG2 4.4Å; L212-I224 HydrophobicContact CB-CD1 4.27Å; L212-I224 HydrophobicContact CD1-CD1 4.3Å; L212-K267 HydrophobicContact CD2-CB 3.64Å; L212-K267 HydrophobicContact CD2-CD 4.44Å; L212-V268 HydrophobicContact CD1-CG2 3.87Å; L212-V268 HydrophobicContact CD2-CG2 4.06Å; L212-K271 HydrophobicContact CD1-CD 4.04Å; L212-K271 HydrophobicContact CG-CD 4.3Å; L212-K271 WeakPolarHBondContact O-CD 3.3Å; L212-K271 WeakPolarHBondContact O-CE 3.48Å; L212-K271 PolarHBondContact O-NZ 3.35Å
213	E	95	Very high	95	Very high	145 Å²	145	74.6 Å²	74.6	68%	0.678	37%	0.37	S	S	*	.	H	α-helix	trans	-70	-42.3	176	-75.5	177.7	-167	0	0	111.7	N209 E210 K271	N209-E213 WeakPolarHBondContact O-CG 3.48Å; N209-E213 PolarHBondContact O-N 3.16Å; E210-E213 PolarHBondContact O-N 2.64Å; E213-K271 PolarHBondContact O-NZ 2.96Å
214	E	95.8	Very high	95.3	Very high	126 Å²	126	71 Å²	71	59%	0.589	35%	0.353	S	S	*	.	H	α-helix	trans	-71.7	-27	-179.6	-69.7	-174.2	160.8	0	0	113.7	E210 Q216	E210-E214 HydrophobicContact CG-CG 4.46Å; E210-E214 WeakPolarHBondContact O-CG 3.47Å; E210-E214 PolarHBondContact O-N 2.91Å; E214-Q216 WeakPolarHBondContact O-CG 3.49Å; E214-Q216 PolarHBondContact O-N 2.97Å; E214-Q216 PolarHBondContact O-NE2 2.94Å
215	A	95.9	Very high	95.4	Very high	5 Å²	5	69.5 Å²	69.5	4%	0.041	35%	0.347	C	S	.	.			trans	-53.9	122.3	180	0	0	0	0	0	111.9	A211 E220 V221 I224 K271	A211-A215 WeakPolarHBondContact O-CB 3.44Å; A211-A215 PolarHBondContact O-N 3.1Å; A215-E220 WeakPolarHBondContact CA-OE2 3.11Å; A215-E220 HydrophobicContact CB-CB 3.84Å; A215-V221 HydrophobicContact CB-CG2 3.59Å; A215-I224 HydrophobicContact CB-CD1 4.38Å; A215-K271 WeakPolarHBondContact O-CE 3.24Å; A215-K271 PolarHBondContact O-NZ 2.9Å
216	Q	94.1	Very high	95.6	Very high	141 Å²	141	74.9 Å²	74.9	66%	0.659	37%	0.371	S	S	*	.			trans	-105.2	-11.7	-177.4	-62.3	-54.9	-52.8	0	0	112.7	E214 E220 F275	E214-Q216 WeakPolarHBondContact O-CG 3.49Å; E214-Q216 PolarHBondContact O-N 2.97Å; E214-Q216 PolarHBondContact O-NE2 2.94Å; Q216-E220 PolarHBondContact N-OE2 3.33Å; Q216-F275 WeakPolarHBondContact O-CE1 3.25Å
217	T	95.8	Very high	95.8	Very high	50 Å²	50	72.5 Å²	72.5	31%	0.307	36%	0.361	S	S	.	.	S	Bend	trans	-122.5	150	-175.9	63.6	0	0	0	0	111.7	E219 E220 V221	T217-E219 WeakPolarHBondContact CB-OE2 3.45Å; T217-E219 PolarHBondContact O-N 3.05Å; T217-E220 PolarHBondContact N-OE2 2.96Å; T217-E220 VanDerWaalsContact N-OE2 3.15Å; T217-E220 PolarHBondContact O-N 3.28Å; T217-E220 WeakPolarHBondContact OG1-CB 3.37Å; T217-E220 WeakPolarHBondContact OG1-CG 3.46Å; T217-E220 PolarHBondContact OG1-N 3.02Å; T217-E220 PolarHBondContact OG1-OE2 3.39Å; T217-E220 VanDerWaalsContact OG1-OE2 3.09Å; T217-V221 PolarHBondContact O-N 3.03Å
218	P	95.2	Very high	95.8	Very high	47 Å²	47	67.4 Å²	67.4	31%	0.305	34%	0.337	S	S	.	.	H	α-helix	trans	-62.6	-27.5	174.6	24.6	-32	0	0	0	112.1	N222 L272 F275	P218-N222 VanDerWaalsContact O-CB 3.3Å; P218-N222 WeakPolarHBondContact O-CB 3.49Å; P218-N222 VanDerWaalsContact O-CG 3.31Å; P218-N222 PolarHBondContact O-N 3.32Å; P218-N222 PolarHBondContact O-ND2 3.39Å; P218-L272 HydrophobicContact CB-CD2 4.3Å; P218-F275 HydrophobicContact CB-CB 4.5Å
219	E	95.8	Very high	95.7	Very high	131 Å²	131	72.2 Å²	72.2	61%	0.612	36%	0.358	S	S	*	.	H	α-helix	trans	-65.3	-45	175.9	-67	72.3	-157.4	0	0	112.2	T217 N222 K223	T217-E219 WeakPolarHBondContact CB-OE2 3.45Å; T217-E219 PolarHBondContact O-N 3.05Å; E219-N222 PolarHBondContact O-N 3.46Å; E219-K223 PolarHBondContact O-N 3.3Å
220	E	95.8	Very high	95.8	Very high	91 Å²	91	72.3 Å²	72.3	43%	0.425	37%	0.366	S	S	.	.	H	α-helix	trans	-62.4	-45.6	176.2	-74.5	162.4	170.8	0	0	111.5	A215 Q216 T217 N222 K223 I224	A215-E220 WeakPolarHBondContact CA-OE2 3.11Å; A215-E220 HydrophobicContact CB-CB 3.84Å; Q216-E220 PolarHBondContact N-OE2 3.33Å; T217-E220 PolarHBondContact N-OE2 2.96Å; T217-E220 VanDerWaalsContact N-OE2 3.15Å; T217-E220 PolarHBondContact O-N 3.28Å; T217-E220 WeakPolarHBondContact OG1-CB 3.37Å; T217-E220 WeakPolarHBondContact OG1-CG 3.46Å; T217-E220 PolarHBondContact OG1-N 3.02Å; T217-E220 PolarHBondContact OG1-OE2 3.39Å; T217-E220 VanDerWaalsContact OG1-OE2 3.09Å; E220-N222 VanDerWaalsContact C-N 3.34Å; E220-N222 PolarHBondContact O-N 3.26Å; E220-K223 WeakPolarHBondContact O-CB 3.46Å; E220-K223 PolarHBondContact O-N 2.85Å; E220-I224 WeakPolarHBondContact O-CG1 3.43Å; E220-I224 PolarHBondContact O-N 2.83Å; E220-I224 VanDerWaalsContact O-N 3.11Å
221	V	96.2	Very high	95.7	Very high	0 Å²	0	69.9 Å²	69.9	0%	0	35%	0.354	C	S	.	.	H	α-helix	trans	-64.3	-40	178	-179.4	0	0	0	0	111.3	L212 A215 T217 K223 I224 G225 V268 K271 L272 F275	L212-V221 HydrophobicContact CD1-CG1 3.93Å; L212-V221 HydrophobicContact CD1-CG2 4.4Å; A215-V221 HydrophobicContact CB-CG2 3.59Å; T217-V221 PolarHBondContact O-N 3.03Å; V221-K223 VanDerWaalsContact C-N 3.33Å; V221-K223 PolarHBondContact O-N 3.47Å; V221-I224 PolarHBondContact O-N 3.5Å; V221-G225 PolarHBondContact O-N 3.26Å; V221-V268 HydrophobicContact CG1-CG1 3.9Å; V221-K271 HydrophobicContact CG1-CB 4.34Å; V221-K271 HydrophobicContact CG2-CD 3.97Å; V221-K271 HydrophobicContact CG2-CG 4.11Å; V221-L272 HydrophobicContact CB-CD2 3.86Å; V221-L272 HydrophobicContact CB-CG 4.3Å; V221-L272 HydrophobicContact CG1-CD1 4.4Å; V221-L272 HydrophobicContact CG1-CD2 3.75Å; V221-L272 HydrophobicContact CG1-CG 3.61Å; V221-F275 HydrophobicContact CG2-CE2 3.89Å
222	N	95.6	Very high	95.6	Very high	76 Å²	76	69 Å²	69	41%	0.406	34%	0.343	S	S	.	.	H	α-helix	trans	-63	-38.7	175.1	-84.3	-52	0	0	0	112.4	P218 E219 E220 G225 Q226 L272	P218-N222 VanDerWaalsContact O-CB 3.3Å; P218-N222 WeakPolarHBondContact O-CB 3.49Å; P218-N222 VanDerWaalsContact O-CG 3.31Å; P218-N222 PolarHBondContact O-N 3.32Å; P218-N222 PolarHBondContact O-ND2 3.39Å; E219-N222 PolarHBondContact O-N 3.46Å; E220-N222 VanDerWaalsContact C-N 3.34Å; E220-N222 PolarHBondContact O-N 3.26Å; N222-G225 CarbonylContact O-C 3.59Å; N222-G225 PolarHBondContact O-N 2.88Å; N222-Q226 WeakPolarHBondContact O-CG 3.1Å; N222-Q226 PolarHBondContact O-N 2.7Å; N222-L272 WeakPolarHBondContact OD1-CD1 3.28Å
223	K	96.7	Very high	95.5	Very high	134 Å²	134	71 Å²	71	58%	0.583	36%	0.36	S	S	*	.	H	α-helix	trans	-60.9	-48.9	175.7	-174	-176	175.5	-170.9	0	111.2	E219 E220 V221 G225 Q226 D227	E219-K223 PolarHBondContact O-N 3.3Å; E220-K223 WeakPolarHBondContact O-CB 3.46Å; E220-K223 PolarHBondContact O-N 2.85Å; V221-K223 VanDerWaalsContact C-N 3.33Å; V221-K223 PolarHBondContact O-N 3.47Å; K223-G225 PolarHBondContact O-N 3.32Å; K223-Q226 WeakPolarHBondContact O-CB 3.13Å; K223-Q226 PolarHBondContact O-N 2.97Å; K223-D227 PolarHBondContact O-N 3.45Å
224	I	96.3	Very high	95.5	Very high	24 Å²	24	68.6 Å²	68.6	12%	0.123	35%	0.353	C	S	.	.	H	α-helix	trans	-58	-40.5	175	-63.4	168.5	0	0	0	110.8	I208 A211 L212 A215 E220 V221 D227 T228 V268	I208-I224 HydrophobicContact CG2-CG2 4.06Å; A211-I224 HydrophobicContact CB-CD1 4.05Å; A211-I224 WeakPolarHBondContact O-CD1 3.49Å; L212-I224 HydrophobicContact CB-CD1 4.27Å; L212-I224 HydrophobicContact CD1-CD1 4.3Å; A215-I224 HydrophobicContact CB-CD1 4.38Å; E220-I224 WeakPolarHBondContact O-CG1 3.43Å; E220-I224 PolarHBondContact O-N 2.83Å; E220-I224 VanDerWaalsContact O-N 3.11Å; V221-I224 PolarHBondContact O-N 3.5Å; I224-D227 PolarHBondContact O-N 2.99Å; I224-T228 WeakPolarHBondContact O-CB 3.27Å; I224-T228 PolarHBondContact O-N 3.41Å; I224-T228 PolarHBondContact O-OG1 3.34Å; I224-V268 HydrophobicContact CG2-CG2 4.14Å
225	G	95.6	Very high	95.4	Very high	5 Å²	5	63.1 Å²	63.1	5%	0.052	33%	0.327	C	S	.	.	H	α-helix	trans	-61.8	-39.9	174.7	0	0	0	0	0	113.8	V221 N222 K223 K229	V221-G225 PolarHBondContact O-N 3.26Å; N222-G225 CarbonylContact O-C 3.59Å; N222-G225 PolarHBondContact O-N 2.88Å; K223-G225 PolarHBondContact O-N 3.32Å; G225-K229 WeakPolarHBondContact O-CB 3.33Å; G225-K229 VanDerWaalsContact O-CG 3.26Å; G225-K229 WeakPolarHBondContact O-CG 3.2Å; G225-K229 PolarHBondContact O-N 3.41Å
226	Q	96.6	Very high	95.4	Very high	136 Å²	136	64.5 Å²	64.5	64%	0.636	34%	0.335	S	S	*	.	H	α-helix	trans	-67.4	-46.4	176.1	-73	175	-2.1	0	0	111.4	N222 K223 T228 K229 G230	N222-Q226 WeakPolarHBondContact O-CG 3.1Å; N222-Q226 PolarHBondContact O-N 2.7Å; K223-Q226 WeakPolarHBondContact O-CB 3.13Å; K223-Q226 PolarHBondContact O-N 2.97Å; Q226-T228 VanDerWaalsContact C-N 3.32Å; Q226-T228 PolarHBondContact O-N 3.24Å; Q226-K229 WeakPolarHBondContact O-CB 3.46Å; Q226-K229 PolarHBondContact O-N 3.36Å; Q226-K229 VanDerWaalsContact O-N 3.17Å; Q226-G230 PolarHBondContact O-N 3.35Å
227	D	95.7	Very high	95.4	Very high	87 Å²	87	64.6 Å²	64.6	47%	0.465	34%	0.336	S	S	.	.	H	α-helix	trans	-61	-43.3	178.1	-65.6	-19.5	0	0	0	110.9	K223 I224 K229 G230 K231	K223-D227 PolarHBondContact O-N 3.45Å; I224-D227 PolarHBondContact O-N 2.99Å; D227-K229 VanDerWaalsContact C-N 3.35Å; D227-K229 PolarHBondContact O-N 3.07Å; D227-G230 PolarHBondContact O-N 3.05Å; D227-K231 WeakPolarHBondContact O-CG 3.11Å; D227-K231 PolarHBondContact O-N 2.93Å; D227-K231 VanDerWaalsContact O-N 3.08Å
228	T	95.6	Very high	95.3	Very high	2 Å²	2	66.8 Å²	66.8	1%	0.012	35%	0.345	C	S	.	.	H	α-helix	trans	-62.7	-40.1	175.9	-58.1	0	0	0	0	112	I224 Q226 K231 L232 Y261 I264	I224-T228 WeakPolarHBondContact O-CB 3.27Å; I224-T228 PolarHBondContact O-N 3.41Å; I224-T228 PolarHBondContact O-OG1 3.34Å; Q226-T228 VanDerWaalsContact C-N 3.32Å; Q226-T228 PolarHBondContact O-N 3.24Å; T228-K231 PolarHBondContact O-N 2.91Å; T228-L232 HydrophobicContact CG2-CD1 4.33Å; T228-L232 WeakPolarHBondContact O-CG 3.48Å; T228-L232 PolarHBondContact O-N 2.98Å; T228-Y261 HydrophobicContact CG2-CD1 4.27Å; T228-I264 HydrophobicContact CG2-CB 4.24Å; T228-I264 HydrophobicContact CG2-CG2 4.08Å
229	K	95	Very high	95.3	Very high	119 Å²	119	64.6 Å²	64.6	52%	0.517	33%	0.33	S	S	.	.	H	α-helix	trans	-65.6	-37.7	175.5	-78.4	173.4	-178.6	177.7	0	112.5	G225 Q226 D227 L232 A233 E265	G225-K229 WeakPolarHBondContact O-CB 3.33Å; G225-K229 VanDerWaalsContact O-CG 3.26Å; G225-K229 WeakPolarHBondContact O-CG 3.2Å; G225-K229 PolarHBondContact O-N 3.41Å; Q226-K229 WeakPolarHBondContact O-CB 3.46Å; Q226-K229 PolarHBondContact O-N 3.36Å; Q226-K229 VanDerWaalsContact O-N 3.17Å; D227-K229 VanDerWaalsContact C-N 3.35Å; D227-K229 PolarHBondContact O-N 3.07Å; K229-L232 PolarHBondContact O-N 3.28Å; K229-A233 PolarHBondContact O-N 3.46Å; K229-E265 VanDerWaalsContact CE-OE1 3.28Å; K229-E265 WeakPolarHBondContact CE-OE1 3.11Å
230	G	96	Very high	95.2	Very high	33 Å²	33	60.7 Å²	60.7	34%	0.34	31%	0.314	S	S	.	.	H	α-helix	trans	-57.8	-52.7	172.2	0	0	0	0	0	111.3	Q226 D227 L232 A233 D234	Q226-G230 PolarHBondContact O-N 3.35Å; D227-G230 PolarHBondContact O-N 3.05Å; G230-L232 VanDerWaalsContact C-N 3.29Å; G230-L232 PolarHBondContact O-N 3.24Å; G230-A233 WeakPolarHBondContact O-CA 3.22Å; G230-A233 WeakPolarHBondContact O-CB 3.5Å; G230-A233 PolarHBondContact O-N 3.46Å; G230-D234 PolarHBondContact O-N 3.41Å
231	K	94.6	Very high	95.1	Very high	64 Å²	64	58.5 Å²	58.5	28%	0.278	31%	0.311	S	S	.	.	H	α-helix	trans	-58.3	-39.4	177.4	-65.6	177.3	-174.8	178.3	0	112.9	E204 D227 T228 A233 D234 L235 Y261	E204-K231 WeakPolarHBondContact OE1-CD 3.07Å; E204-K231 WeakPolarHBondContact OE1-CE 3.41Å; E204-K231 IonicContact OE1-NZ 2.63Å; E204-K231 PolarHBondContact OE1-NZ 3.35Å; D227-K231 WeakPolarHBondContact O-CG 3.11Å; D227-K231 PolarHBondContact O-N 2.93Å; D227-K231 VanDerWaalsContact O-N 3.08Å; T228-K231 PolarHBondContact O-N 2.91Å; K231-A233 VanDerWaalsContact C-N 3.34Å; K231-D234 PolarHBondContact O-N 2.91Å; K231-L235 WeakPolarHBondContact O-CB 3.32Å; K231-L235 WeakPolarHBondContact O-CG 3.32Å; K231-L235 PolarHBondContact O-N 2.95Å; K231-Y261 HydrophobicContact CB-CD1 4.47Å; K231-Y261 HydrophobicContact CB-CE1 4.27Å; K231-Y261 HydrophobicContact CB-CE2 4.4Å; K231-Y261 HydrophobicContact CD-CD1 4.27Å; K231-Y261 HydrophobicContact CD-CE1 3.47Å; K231-Y261 VanDerWaalsContact CD-CE1 3.47Å; K231-Y261 HydrophobicContact CG-CE1 4.49Å
232	L	94.3	Very high	95	Very high	24 Å²	24	58.8 Å²	58.8	13%	0.126	31%	0.313	C	S	.	.	H	α-helix	trans	-65.2	-35.8	174.9	-75.9	170.8	0	0	0	112.7	T228 K229 G230 T236 M258 E265	T228-L232 HydrophobicContact CG2-CD1 4.33Å; T228-L232 WeakPolarHBondContact O-CG 3.48Å; T228-L232 PolarHBondContact O-N 2.98Å; K229-L232 PolarHBondContact O-N 3.28Å; G230-L232 VanDerWaalsContact C-N 3.29Å; G230-L232 PolarHBondContact O-N 3.24Å; L232-T236 WeakPolarHBondContact O-CB 3.33Å; L232-T236 PolarHBondContact O-N 3.45Å; L232-T236 PolarHBondContact O-OG1 3.45Å; L232-M258 HydrophobicContact CD2-CG 3.78Å; L232-E265 HydrophobicContact CD1-CB 4.47Å
233	A	94.2	Very high	94.8	Very high	50 Å²	50	56.4 Å²	56.4	41%	0.413	30%	0.301	S	S	.	.	H	α-helix	trans	-66.9	-46.6	175.2	0	0	0	0	0	110.9	K229 G230 K231 L235 T236 E237	K229-A233 PolarHBondContact O-N 3.46Å; G230-A233 WeakPolarHBondContact O-CA 3.22Å; G230-A233 WeakPolarHBondContact O-CB 3.5Å; G230-A233 PolarHBondContact O-N 3.46Å; K231-A233 VanDerWaalsContact C-N 3.34Å; A233-L235 PolarHBondContact O-N 3.15Å; A233-T236 WeakPolarHBondContact O-CA 3.41Å; A233-T236 VanDerWaalsContact O-CB 3.27Å; A233-T236 WeakPolarHBondContact O-CB 3.37Å; A233-T236 PolarHBondContact O-N 2.9Å; A233-E237 PolarHBondContact O-N 2.91Å; A233-E237 VanDerWaalsContact O-N 3.16Å
234	D	95.1	Very high	94.5	Very high	96 Å²	96	58 Å²	58	51%	0.513	31%	0.31	S	S	.	.	H	α-helix	trans	-59.7	-46	177.1	-59.4	-24.5	0	0	0	111.3	G230 K231 T236 E237 L238	G230-D234 PolarHBondContact O-N 3.41Å; K231-D234 PolarHBondContact O-N 2.91Å; D234-T236 PolarHBondContact O-N 3.44Å; D234-E237 PolarHBondContact O-N 3.15Å; D234-L238 WeakPolarHBondContact O-CG 3.42Å; D234-L238 PolarHBondContact O-N 2.93Å
235	L	94.7	Very high	94.4	Very high	10 Å²	10	62.7 Å²	62.7	5%	0.052	33%	0.331	C	S	.	.	H	α-helix	trans	-60.6	-35.2	174.6	-75.8	174.8	0	0	0	112.4	K231 A233 E237 L238 I239 L254 Q257 M258 Y261	K231-L235 WeakPolarHBondContact O-CB 3.32Å; K231-L235 WeakPolarHBondContact O-CG 3.32Å; K231-L235 PolarHBondContact O-N 2.95Å; A233-L235 PolarHBondContact O-N 3.15Å; L235-E237 VanDerWaalsContact C-N 3.35Å; L235-L238 PolarHBondContact O-N 2.94Å; L235-I239 WeakPolarHBondContact O-CB 3.43Å; L235-I239 VanDerWaalsContact O-CD1 3.3Å; L235-I239 WeakPolarHBondContact O-CD1 3.39Å; L235-I239 WeakPolarHBondContact O-CG1 3.46Å; L235-I239 PolarHBondContact O-N 2.96Å; L235-L254 HydrophobicContact CD2-CD2 3.77Å; L235-Q257 HydrophobicContact CD1-CB 4.23Å; L235-Q257 HydrophobicContact CD2-CB 4.4Å; L235-M258 HydrophobicContact CB-CE 4.06Å; L235-M258 HydrophobicContact CD1-CB 4.2Å; L235-Y261 HydrophobicContact CD1-CD2 3.49Å; L235-Y261 VanDerWaalsContact CD1-CD2 3.49Å; L235-Y261 HydrophobicContact CD1-CE2 3.77Å
236	T	93.9	Very high	94.1	Very high	34 Å²	34	64.8 Å²	64.8	21%	0.209	35%	0.353	C	S	.	.	H	α-helix	trans	-62.9	-44.3	178.6	-62.6	0	0	0	0	110.6	F123 L232 A233 D234 I239 D240 M258	F123-T236 HydrophobicContact CD1-CG2 4.18Å; F123-T236 HydrophobicContact CE1-CG2 3.56Å; F123-T236 WeakPolarHBondContact CE1-O 3.42Å; L232-T236 WeakPolarHBondContact O-CB 3.33Å; L232-T236 PolarHBondContact O-N 3.45Å; L232-T236 PolarHBondContact O-OG1 3.45Å; A233-T236 WeakPolarHBondContact O-CA 3.41Å; A233-T236 VanDerWaalsContact O-CB 3.27Å; A233-T236 WeakPolarHBondContact O-CB 3.37Å; A233-T236 PolarHBondContact O-N 2.9Å; D234-T236 PolarHBondContact O-N 3.44Å; T236-I239 PolarHBondContact O-N 3.37Å; T236-D240 WeakPolarHBondContact O-CB 3.37Å; T236-D240 PolarHBondContact O-N 2.93Å; T236-M258 WeakPolarHBondContact OG1-CE 3.47Å
237	E	94.2	Very high	94	Very high	144 Å²	144	63.5 Å²	63.5	67%	0.673	35%	0.345	S	S	*	.	H	α-helix	trans	-65.7	-43.6	177	-64.3	-175.1	176.3	0	0	111.9	A233 D234 L235 I239 D240 A241	A233-E237 PolarHBondContact O-N 2.91Å; A233-E237 VanDerWaalsContact O-N 3.16Å; D234-E237 PolarHBondContact O-N 3.15Å; L235-E237 VanDerWaalsContact C-N 3.35Å; E237-I239 PolarHBondContact O-N 3.39Å; E237-D240 PolarHBondContact O-N 3.24Å; E237-A241 PolarHBondContact O-N 3.42Å
238	L	95.1	Very high	93.8	Very high	96 Å²	96	61.4 Å²	61.4	50%	0.503	33%	0.334	S	S	.	.	H	α-helix	trans	-63.2	-40.3	177.6	-67.8	173	0	0	0	112.3	D234 L235 A242 L254	D234-L238 WeakPolarHBondContact O-CG 3.42Å; D234-L238 PolarHBondContact O-N 2.93Å; L235-L238 PolarHBondContact O-N 2.94Å; L238-A242 WeakPolarHBondContact O-CB 3.5Å; L238-A242 PolarHBondContact O-N 2.96Å; L238-L254 HydrophobicContact CB-CD1 3.84Å; L238-L254 HydrophobicContact CB-CD2 4.31Å; L238-L254 HydrophobicContact CD1-CD2 4.3Å
239	I	94.4	Very high	93.6	Very high	0 Å²	0	66.7 Å²	66.7	0%	0	36%	0.362	C	S	.	.	H	α-helix	trans	-66.6	-44.3	177	-70.3	161.8	0	0	0	110.6	F123 L235 T236 E237 A241 A242 L243 L254 L255 M258	F123-I239 HydrophobicContact CD1-CB 4.39Å; F123-I239 HydrophobicContact CD1-CG2 4.01Å; F123-I239 HydrophobicContact CD2-CG2 3.99Å; F123-I239 HydrophobicContact CE1-CB 4Å; F123-I239 HydrophobicContact CE1-CG2 3.82Å; F123-I239 HydrophobicContact CE2-CG2 3.81Å; F123-I239 HydrophobicContact CG-CG2 4.08Å; F123-I239 HydrophobicContact CZ-CB 4.21Å; F123-I239 HydrophobicContact CZ-CD1 4.35Å; F123-I239 HydrophobicContact CZ-CG2 3.72Å; L235-I239 WeakPolarHBondContact O-CB 3.43Å; L235-I239 VanDerWaalsContact O-CD1 3.3Å; L235-I239 WeakPolarHBondContact O-CD1 3.39Å; L235-I239 WeakPolarHBondContact O-CG1 3.46Å; L235-I239 PolarHBondContact O-N 2.96Å; T236-I239 PolarHBondContact O-N 3.37Å; E237-I239 PolarHBondContact O-N 3.39Å; I239-A241 VanDerWaalsContact C-N 3.32Å; I239-A241 PolarHBondContact O-N 3.42Å; I239-A242 PolarHBondContact O-N 3.04Å; I239-L243 HydrophobicContact CG2-CD1 3.66Å; I239-L243 HydrophobicContact CG2-CG 4.2Å; I239-L243 WeakPolarHBondContact O-CB 3.48Å; I239-L243 VanDerWaalsContact O-CG 3.29Å; I239-L243 WeakPolarHBondContact O-CG 3.31Å; I239-L243 PolarHBondContact O-N 3.36Å; I239-L254 HydrophobicContact CD1-CB 4.07Å; I239-L254 HydrophobicContact CG1-CB 3.44Å; I239-L254 VanDerWaalsContact CG1-CB 3.44Å; I239-L254 HydrophobicContact CG1-CD1 4.09Å; I239-L254 HydrophobicContact CG1-CG 4.4Å; I239-L255 HydrophobicContact CD1-CD2 3.89Å; I239-L255 HydrophobicContact CD1-CG 3.99Å; I239-L255 HydrophobicContact CG1-CG 4.44Å; I239-L255 HydrophobicContact CG2-CD2 4.48Å; I239-L255 HydrophobicContact CG2-CG 4.36Å; I239-M258 HydrophobicContact CD1-CB 4.33Å; I239-M258 HydrophobicContact CD1-CE 3.49Å; I239-M258 VanDerWaalsContact CD1-CE 3.49Å; I239-M258 HydrophobicContact CD1-SD 4Å
240	D	93.3	Very high	93.4	Very high	50 Å²	50	63.9 Å²	63.9	27%	0.267	36%	0.355	S	S	.	.	H	α-helix	trans	-58.7	-45.9	177.5	-162.5	45.3	0	0	0	110.7	F123 T124 T236 E237 L243 H244	F123-D240 HydrophobicContact CB-CB 4.33Å; F123-D240 VanDerWaalsContact CB-OD1 3.31Å; F123-D240 WeakPolarHBondContact CB-OD1 3.38Å; F123-D240 HydrophobicContact CD1-CB 4.04Å; F123-D240 PolarHBondContact N-OD1 3.01Å; T124-D240 PolarHBondContact N-OD1 3.31Å; T124-D240 PolarHBondContact OG1-OD1 3.37Å; T124-D240 PolarHBondContact OG1-OD2 3.23Å; T236-D240 WeakPolarHBondContact O-CB 3.37Å; T236-D240 PolarHBondContact O-N 2.93Å; E237-D240 PolarHBondContact O-N 3.24Å; D240-L243 PolarHBondContact O-N 2.86Å; D240-H244 WeakPolarHBondContact O-CB 3.33Å; D240-H244 PolarHBondContact O-N 2.93Å
241	A	94.3	Very high	93.3	Very high	44 Å²	44	62.3 Å²	62.3	36%	0.364	34%	0.339	S	S	.	.	H	α-helix	trans	-62.3	-47.2	175.6	0	0	0	0	0	112.5	E237 I239 L243 H244 E245	E237-A241 PolarHBondContact O-N 3.42Å; I239-A241 VanDerWaalsContact C-N 3.32Å; I239-A241 PolarHBondContact O-N 3.42Å; A241-L243 VanDerWaalsContact C-N 3.35Å; A241-L243 PolarHBondContact O-N 3.04Å; A241-H244 PolarHBondContact O-N 3.41Å; A241-E245 WeakPolarHBondContact O-CG 3.48Å; A241-E245 PolarHBondContact O-N 2.92Å
242	A	94.3	Very high	93.1	Very high	6 Å²	6	61.6 Å²	61.6	5%	0.05	34%	0.336	C	S	.	.	H	α-helix	trans	-62	-41.3	179.7	0	0	0	0	0	112.3	L238 I239 E245 G246 K247 T250 A251 L254	L238-A242 WeakPolarHBondContact O-CB 3.5Å; L238-A242 PolarHBondContact O-N 2.96Å; I239-A242 PolarHBondContact O-N 3.04Å; A242-E245 PolarHBondContact O-N 2.88Å; A242-G246 PolarHBondContact O-N 3.23Å; A242-K247 HydrophobicContact CB-CB 4.48Å; A242-K247 PolarHBondContact O-N 3.48Å; A242-T250 HydrophobicContact CB-CG2 4.34Å; A242-A251 HydrophobicContact CB-CB 4.09Å; A242-L254 HydrophobicContact CB-CD1 4.26Å
243	L	91.4	Very high	92.9	Very high	26 Å²	26	65.6 Å²	65.6	14%	0.136	35%	0.354	C	S	.	.	H	α-helix	trans	-66.7	-40.3	175.4	-71.4	171.3	0	0	0	111.5	F123 M181 L182 I239 D240 A241 E245 G246 L248 A251	F123-L243 HydrophobicContact CB-CD1 3.79Å; F123-L243 HydrophobicContact CD2-CD1 3.93Å; F123-L243 HydrophobicContact CG-CD1 4.03Å; M181-L243 HydrophobicContact CE-CD1 4.04Å; M181-L243 HydrophobicContact SD-CD1 4.07Å; L182-L243 HydrophobicContact CD2-CD2 3.74Å; I239-L243 HydrophobicContact CG2-CD1 3.66Å; I239-L243 HydrophobicContact CG2-CG 4.2Å; I239-L243 WeakPolarHBondContact O-CB 3.48Å; I239-L243 VanDerWaalsContact O-CG 3.29Å; I239-L243 WeakPolarHBondContact O-CG 3.31Å; I239-L243 PolarHBondContact O-N 3.36Å; D240-L243 PolarHBondContact O-N 2.86Å; A241-L243 VanDerWaalsContact C-N 3.35Å; A241-L243 PolarHBondContact O-N 3.04Å; L243-E245 VanDerWaalsContact C-N 3.33Å; L243-E245 PolarHBondContact O-N 2.85Å; L243-G246 PolarHBondContact O-N 3.04Å; L243-L248 HydrophobicContact CD2-CD2 4.44Å; L243-A251 HydrophobicContact CD2-CB 3.74Å; L243-A251 HydrophobicContact CG-CB 3.98Å
244	H	90.5	Very high	92.9	Very high	169 Å²	169	64.3 Å²	64.3	78%	0.782	34%	0.34	S	S	*	.	H	α-helix	trans	-64.5	-37.1	177.3	-167.3	65.1	0	0	0	112.7	D240 A241 G246	D240-H244 WeakPolarHBondContact O-CB 3.33Å; D240-H244 PolarHBondContact O-N 2.93Å; A241-H244 PolarHBondContact O-N 3.41Å; H244-G246 VanDerWaalsContact C-N 3.27Å; H244-G246 PolarHBondContact O-N 3.29Å
245	E	93.1	Very high	92.8	Very high	121 Å²	121	59.7 Å²	59.7	57%	0.565	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-4.4	176.2	-68.1	-179.1	-170.7	0	0	113.8	A241 A242 L243 K247	A241-E245 WeakPolarHBondContact O-CG 3.48Å; A241-E245 PolarHBondContact O-N 2.92Å; A242-E245 PolarHBondContact O-N 2.88Å; L243-E245 VanDerWaalsContact C-N 3.33Å; L243-E245 PolarHBondContact O-N 2.85Å; E245-K247 VanDerWaalsContact C-N 3.26Å; E245-K247 HydrophobicContact CB-CD 4.33Å; E245-K247 HydrophobicContact CB-CG 4.23Å; E245-K247 PolarHBondContact O-N 2.93Å; E245-K247 WeakPolarHBondContact OE2-CD 3.44Å; E245-K247 WeakPolarHBondContact OE2-CE 3.37Å; E245-K247 IonicContact OE2-NZ 2.64Å; E245-K247 PolarHBondContact OE2-NZ 3.44Å
246	G	90.8	Very high	92.6	Very high	50 Å²	50	60.4 Å²	60.4	52%	0.515	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	71.3	17.5	-176.5	0	0	0	0	0	114.2	A242 L243 H244 L248	A242-G246 PolarHBondContact O-N 3.23Å; L243-G246 PolarHBondContact O-N 3.04Å; H244-G246 VanDerWaalsContact C-N 3.27Å; H244-G246 PolarHBondContact O-N 3.29Å; G246-L248 PolarHBondContact O-N 2.91Å
247	K	93.7	Very high	92.5	Very high	108 Å²	108	61.5 Å²	61.5	47%	0.47	32%	0.323	S	S	.	.			trans	-81.9	71.7	176.9	-69.5	177.3	178.7	163.2	0	110.4	A242 E245 D249 T250 A251	A242-K247 HydrophobicContact CB-CB 4.48Å; A242-K247 PolarHBondContact O-N 3.48Å; E245-K247 VanDerWaalsContact C-N 3.26Å; E245-K247 HydrophobicContact CB-CD 4.33Å; E245-K247 HydrophobicContact CB-CG 4.23Å; E245-K247 PolarHBondContact O-N 2.93Å; E245-K247 WeakPolarHBondContact OE2-CD 3.44Å; E245-K247 WeakPolarHBondContact OE2-CE 3.37Å; E245-K247 IonicContact OE2-NZ 2.64Å; E245-K247 PolarHBondContact OE2-NZ 3.44Å; K247-D249 PolarHBondContact O-N 2.84Å; K247-T250 PolarHBondContact O-N 3.19Å; K247-A251 PolarHBondContact O-N 2.97Å
248	L	91.3	Very high	92.5	Very high	43 Å²	43	54.9 Å²	54.9	23%	0.225	29%	0.292	C	S	.	.	H	α-helix	trans	-58.5	-46.7	-173.6	-74.1	-164.3	0	0	0	113.3	L182 E185 M187 L243 G246 T250 A251 K252	L182-L248 HydrophobicContact CD2-CD2 4.19Å; E185-L248 HydrophobicContact CB-CD1 3.82Å; E185-L248 HydrophobicContact CB-CD2 4.35Å; E185-L248 HydrophobicContact CG-CD1 4.28Å; E185-L248 HydrophobicContact CG-CD2 4.1Å; M187-L248 HydrophobicContact CE-CB 3.39Å; M187-L248 HydrophobicContact CE-CD1 4.18Å; M187-L248 HydrophobicContact CE-CD2 4.3Å; M187-L248 HydrophobicContact CE-CG 4.14Å; M187-L248 WeakPolarHBondContact CE-O 3.21Å; M187-L248 HydrophobicContact SD-CB 3.81Å; M187-L248 HydrophobicContact SD-CD1 4.33Å; L243-L248 HydrophobicContact CD2-CD2 4.44Å; G246-L248 PolarHBondContact O-N 2.91Å; L248-T250 VanDerWaalsContact C-N 3.34Å; L248-T250 PolarHBondContact O-N 3.45Å; L248-A251 PolarHBondContact O-N 2.81Å; L248-K252 WeakPolarHBondContact O-CB 3.13Å; L248-K252 PolarHBondContact O-N 3.48Å
249	D	90.8	Very high	92.4	Very high	114 Å²	114	54 Å²	54	61%	0.61	28%	0.284	S	S	*	.	H	α-helix	trans	-62	-40.5	177.9	-66.4	-50.6	0	0	0	112.4	K247 K252 E253	K247-D249 PolarHBondContact O-N 2.84Å; D249-K252 VanDerWaalsContact O-CB 3.24Å; D249-K252 WeakPolarHBondContact O-CB 3.23Å; D249-K252 PolarHBondContact O-N 3.47Å; D249-E253 PolarHBondContact O-N 3.05Å
250	T	92	Very high	92.3	Very high	60 Å²	60	58 Å²	58	37%	0.368	30%	0.3	S	S	.	.	H	α-helix	trans	-64.8	-44.3	175.6	-52.4	0	0	0	0	111.3	A242 K247 L248 K252 E253 L254	A242-T250 HydrophobicContact CB-CG2 4.34Å; K247-T250 PolarHBondContact O-N 3.19Å; L248-T250 VanDerWaalsContact C-N 3.34Å; L248-T250 PolarHBondContact O-N 3.45Å; T250-K252 PolarHBondContact O-N 2.84Å; T250-E253 PolarHBondContact O-N 2.92Å; T250-L254 HydrophobicContact CG2-CD1 4.03Å; T250-L254 HydrophobicContact CG2-CG 4.45Å; T250-L254 VanDerWaalsContact O-CG 3.3Å; T250-L254 WeakPolarHBondContact O-CG 3.22Å; T250-L254 PolarHBondContact O-N 3.01Å
251	A	93.1	Very high	92.3	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-60.1	-36.6	174.9	0	0	0	0	0	111.6	L182 A242 L243 K247 L248 L255	L182-A251 HydrophobicContact CD2-CB 4.17Å; A242-A251 HydrophobicContact CB-CB 4.09Å; L243-A251 HydrophobicContact CD2-CB 3.74Å; L243-A251 HydrophobicContact CG-CB 3.98Å; K247-A251 PolarHBondContact O-N 2.97Å; L248-A251 PolarHBondContact O-N 2.81Å; A251-L255 VanDerWaalsContact O-CB 3.3Å; A251-L255 WeakPolarHBondContact O-CB 3.25Å; A251-L255 WeakPolarHBondContact O-CD1 3.4Å; A251-L255 VanDerWaalsContact O-CG 3.31Å; A251-L255 WeakPolarHBondContact O-CG 2.9Å; A251-L255 PolarHBondContact O-N 3.46Å
252	K	91.4	Very high	92.3	Very high	49 Å²	49	55.1 Å²	55.1	21%	0.213	28%	0.281	C	S	.	.	H	α-helix	trans	-62.3	-46.8	175.6	-165.8	-165.8	169.9	-158.9	0	112.2	L182 M187 L189 D194 L248 D249 T250 T256	L182-K252 HydrophobicContact CD1-CB 4.06Å; L182-K252 HydrophobicContact CD1-CG 4.24Å; M187-K252 HydrophobicContact CE-CB 4.46Å; L189-K252 HydrophobicContact CD2-CB 4.42Å; L189-K252 HydrophobicContact CD2-CD 3.91Å; L189-K252 HydrophobicContact CD2-CG 3.17Å; D194-K252 WeakPolarHBondContact OD1-CE 3.34Å; D194-K252 IonicContact OD1-NZ 2.74Å; D194-K252 PolarHBondContact OD1-NZ 2.93Å; D194-K252 IonicContact OD2-NZ 3.78Å; L248-K252 WeakPolarHBondContact O-CB 3.13Å; L248-K252 PolarHBondContact O-N 3.48Å; D249-K252 VanDerWaalsContact O-CB 3.24Å; D249-K252 WeakPolarHBondContact O-CB 3.23Å; D249-K252 PolarHBondContact O-N 3.47Å; T250-K252 PolarHBondContact O-N 2.84Å; K252-T256 PolarHBondContact O-N 3.33Å; K252-T256 PolarHBondContact O-OG1 3.41Å
253	E	90.3	Very high	92.2	Very high	107 Å²	107	58.8 Å²	58.8	50%	0.5	30%	0.299	S	S	.	.	H	α-helix	trans	-63.1	-47.5	176.7	-71.2	173.4	176	0	0	111.3	D249 T250 L255 T256 Q257	D249-E253 PolarHBondContact O-N 3.05Å; T250-E253 PolarHBondContact O-N 2.92Å; E253-L255 PolarHBondContact O-N 3.48Å; E253-T256 WeakPolarHBondContact O-CA 3.42Å; E253-T256 VanDerWaalsContact O-CB 3.29Å; E253-T256 WeakPolarHBondContact O-CB 3.37Å; E253-T256 PolarHBondContact O-N 3.45Å; E253-T256 VanDerWaalsContact O-N 3.1Å; E253-Q257 PolarHBondContact O-N 3.45Å
254	L	93.2	Very high	92.4	Very high	23 Å²	23	57.6 Å²	57.6	12%	0.12	29%	0.293	C	S	.	.	H	α-helix	trans	-63.1	-40.1	178.5	-67.1	168.8	0	0	0	112.4	L235 L238 I239 A242 T250 T256 Q257 M258	L235-L254 HydrophobicContact CD2-CD2 3.77Å; L238-L254 HydrophobicContact CB-CD1 3.84Å; L238-L254 HydrophobicContact CB-CD2 4.31Å; L238-L254 HydrophobicContact CD1-CD2 4.3Å; I239-L254 HydrophobicContact CD1-CB 4.07Å; I239-L254 HydrophobicContact CG1-CB 3.44Å; I239-L254 VanDerWaalsContact CG1-CB 3.44Å; I239-L254 HydrophobicContact CG1-CD1 4.09Å; I239-L254 HydrophobicContact CG1-CG 4.4Å; A242-L254 HydrophobicContact CB-CD1 4.26Å; T250-L254 HydrophobicContact CG2-CD1 4.03Å; T250-L254 HydrophobicContact CG2-CG 4.45Å; T250-L254 VanDerWaalsContact O-CG 3.3Å; T250-L254 WeakPolarHBondContact O-CG 3.22Å; T250-L254 PolarHBondContact O-N 3.01Å; L254-T256 VanDerWaalsContact C-N 3.27Å; L254-T256 PolarHBondContact O-N 2.82Å; L254-Q257 PolarHBondContact O-N 2.84Å; L254-M258 WeakPolarHBondContact O-CB 3.14Å; L254-M258 PolarHBondContact O-N 3Å
255	L	92.9	Very high	92.6	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-65.5	-32.5	174.4	-80.5	165.1	0	0	0	112.2	L175 L179 L182 I239 A251 E253 M258 K259	L175-L255 HydrophobicContact CD1-CD2 4.21Å; L179-L255 HydrophobicContact CD2-CB 4.39Å; L179-L255 HydrophobicContact CD2-CD1 4.45Å; L182-L255 HydrophobicContact CD1-CD1 3.54Å; L182-L255 HydrophobicContact CG-CD1 3.83Å; I239-L255 HydrophobicContact CD1-CD2 3.89Å; I239-L255 HydrophobicContact CD1-CG 3.99Å; I239-L255 HydrophobicContact CG1-CG 4.44Å; I239-L255 HydrophobicContact CG2-CD2 4.48Å; I239-L255 HydrophobicContact CG2-CG 4.36Å; A251-L255 VanDerWaalsContact O-CB 3.3Å; A251-L255 WeakPolarHBondContact O-CB 3.25Å; A251-L255 WeakPolarHBondContact O-CD1 3.4Å; A251-L255 VanDerWaalsContact O-CG 3.31Å; A251-L255 WeakPolarHBondContact O-CG 2.9Å; A251-L255 PolarHBondContact O-N 3.46Å; E253-L255 PolarHBondContact O-N 3.48Å; L255-M258 HydrophobicContact CD2-SD 4.28Å; L255-M258 PolarHBondContact O-N 3.21Å; L255-K259 PolarHBondContact O-N 3.38Å
256	T	90.1	Very high	92.7	Very high	25 Å²	25	50.7 Å²	50.7	15%	0.153	26%	0.261	C	S	.	.	H	α-helix	trans	-65.1	-45	173.2	-57.5	0	0	0	0	110.4	K252 E253 L254 K259 Y260	K252-T256 PolarHBondContact O-N 3.33Å; K252-T256 PolarHBondContact O-OG1 3.41Å; E253-T256 WeakPolarHBondContact O-CA 3.42Å; E253-T256 VanDerWaalsContact O-CB 3.29Å; E253-T256 WeakPolarHBondContact O-CB 3.37Å; E253-T256 PolarHBondContact O-N 3.45Å; E253-T256 VanDerWaalsContact O-N 3.1Å; L254-T256 VanDerWaalsContact C-N 3.27Å; L254-T256 PolarHBondContact O-N 2.82Å; T256-K259 VanDerWaalsContact O-CB 3.32Å; T256-K259 WeakPolarHBondContact O-CB 3.39Å; T256-K259 PolarHBondContact O-N 3.12Å; T256-Y260 HydrophobicContact CG2-CE2 4.05Å; T256-Y260 WeakPolarHBondContact O-CD2 3.23Å
257	Q	92.1	Very high	92.9	Very high	57 Å²	57	53.1 Å²	53.1	27%	0.266	26%	0.258	S	S	.	.	H	α-helix	trans	-61.5	-45.5	173.6	-65.4	178.8	3.8	0	0	111.9	F201 L235 E253 L254 K259 Y260 Y261	F201-Q257 HydrophobicContact CD1-CG 4.29Å; F201-Q257 HydrophobicContact CD2-CG 4.12Å; F201-Q257 HydrophobicContact CE1-CB 4.44Å; F201-Q257 HydrophobicContact CE1-CG 4.1Å; F201-Q257 HydrophobicContact CE2-CB 3.89Å; F201-Q257 HydrophobicContact CE2-CG 3.91Å; F201-Q257 HydrophobicContact CG-CG 4.29Å; F201-Q257 HydrophobicContact CZ-CB 3.82Å; F201-Q257 HydrophobicContact CZ-CG 3.9Å; L235-Q257 HydrophobicContact CD1-CB 4.23Å; L235-Q257 HydrophobicContact CD2-CB 4.4Å; E253-Q257 PolarHBondContact O-N 3.45Å; L254-Q257 PolarHBondContact O-N 2.84Å; Q257-K259 PolarHBondContact O-N 3.33Å; Q257-Y260 PolarHBondContact O-N 3.47Å; Q257-Y261 WeakPolarHBondContact O-CD2 3.49Å; Q257-Y261 PolarHBondContact O-N 2.88Å
258	M	94.2	Very high	93	Very high	4 Å²	4	48.3 Å²	48.3	2%	0.02	24%	0.237	C	C	.	.	H	α-helix	trans	-56.5	-37	176.5	-178.6	178	-82.5	0	0	112	F123 P174 L175 L232 L235 T236 I239 L254 L255 Y260 Y261 A262	F123-M258 HydrophobicContact CZ-CE 4.31Å; F123-M258 HydrophobicContact CZ-SD 4.5Å; P174-M258 HydrophobicContact CB-CE 4.43Å; P174-M258 HydrophobicContact CB-SD 4.17Å; L175-M258 HydrophobicContact CB-CG 4.44Å; L175-M258 HydrophobicContact CB-SD 4.15Å; L175-M258 HydrophobicContact CD1-CB 4.34Å; L175-M258 HydrophobicContact CD1-CG 4.19Å; L175-M258 HydrophobicContact CD1-SD 4.4Å; L232-M258 HydrophobicContact CD2-CG 3.78Å; L235-M258 HydrophobicContact CB-CE 4.06Å; L235-M258 HydrophobicContact CD1-CB 4.2Å; T236-M258 WeakPolarHBondContact OG1-CE 3.47Å; I239-M258 HydrophobicContact CD1-CB 4.33Å; I239-M258 HydrophobicContact CD1-CE 3.49Å; I239-M258 VanDerWaalsContact CD1-CE 3.49Å; I239-M258 HydrophobicContact CD1-SD 4Å; L254-M258 WeakPolarHBondContact O-CB 3.14Å; L254-M258 PolarHBondContact O-N 3Å; L255-M258 HydrophobicContact CD2-SD 4.28Å; L255-M258 PolarHBondContact O-N 3.21Å; M258-Y260 VanDerWaalsContact C-N 3.33Å; M258-Y260 PolarHBondContact O-N 3.24Å; M258-Y261 PolarHBondContact O-N 2.85Å; M258-A262 VanDerWaalsContact O-CB 3.28Å; M258-A262 WeakPolarHBondContact O-CB 3.24Å; M258-A262 PolarHBondContact O-N 3.02Å
259	K	92.3	Very high	93.2	Very high	77 Å²	77	50.6 Å²	50.6	34%	0.335	25%	0.246	S	C	.	.	H	α-helix	trans	-58.3	-42.9	175.7	-173.4	-178.9	179.2	174.9	0	112.1	L175 L255 T256 Q257 N263	L175-K259 HydrophobicContact CD1-CB 4.14Å; L175-K259 HydrophobicContact CD2-CB 4.22Å; L175-K259 HydrophobicContact CD2-CG 4.27Å; L255-K259 PolarHBondContact O-N 3.38Å; T256-K259 VanDerWaalsContact O-CB 3.32Å; T256-K259 WeakPolarHBondContact O-CB 3.39Å; T256-K259 PolarHBondContact O-N 3.12Å; Q257-K259 PolarHBondContact O-N 3.33Å; K259-N263 VanDerWaalsContact O-CG 3.26Å; K259-N263 PolarHBondContact O-N 3.02Å; K259-N263 VanDerWaalsContact O-N 3.11Å; K259-N263 PolarHBondContact O-ND2 3.15Å
260	Y	92.4	Very high	93.4	Very high	84 Å²	84	47.5 Å²	47.5	33%	0.329	24%	0.236	S	C	.	.	H	α-helix	trans	-70.1	-44.6	179.8	-72.4	-79.3	0	0	0	112.2	F201 L205 T256 Q257 M258 A262 N263 I264	F201-Y260 AromaticContact CE1-CD2 3.71Å; F201-Y260 HydrophobicContact CE1-CD2 3.71Å; F201-Y260 HydrophobicContact CE1-CE2 4.33Å; F201-Y260 HydrophobicContact CE1-CG 4.16Å; F201-Y260 HydrophobicContact CZ-CD2 4.03Å; F201-Y260 HydrophobicContact CZ-CG 4.24Å; L205-Y260 HydrophobicContact CD2-CD1 3.5Å; L205-Y260 HydrophobicContact CD2-CE1 4.08Å; L205-Y260 HydrophobicContact CD2-CG 3.99Å; T256-Y260 HydrophobicContact CG2-CE2 4.05Å; T256-Y260 WeakPolarHBondContact O-CD2 3.23Å; Q257-Y260 PolarHBondContact O-N 3.47Å; M258-Y260 VanDerWaalsContact C-N 3.33Å; M258-Y260 PolarHBondContact O-N 3.24Å; Y260-A262 VanDerWaalsContact C-N 3.31Å; Y260-A262 PolarHBondContact O-N 3.47Å; Y260-N263 WeakPolarHBondContact O-CB 3.36Å; Y260-N263 PolarHBondContact O-N 2.9Å; Y260-N263 VanDerWaalsContact O-N 3.14Å; Y260-I264 WeakPolarHBondContact O-CG1 3.08Å; Y260-I264 PolarHBondContact O-N 2.87Å
261	Y	94.5	Very high	93.5	Very high	11 Å²	11	46.6 Å²	46.6	4%	0.043	23%	0.227	C	C	.	.	H	α-helix	trans	-64.7	-35.3	175.3	-70.3	-65.3	0	0	0	112.5	F201 E204 I208 T228 K231 L235 Q257 M258 N263 I264 E265	F201-Y261 HydrophobicContact CD2-CE2 4.43Å; F201-Y261 HydrophobicContact CE2-CD2 4.25Å; F201-Y261 AromaticContact CE2-CE2 3.51Å; F201-Y261 HydrophobicContact CE2-CE2 3.51Å; F201-Y261 AromaticContact CE2-CZ 3.73Å; F201-Y261 HydrophobicContact CZ-CE2 4.32Å; E204-Y261 PolarHBondContact OE1-OH 3.39Å; E204-Y261 PolarHBondContact OE2-OH 3.41Å; I208-Y261 HydrophobicContact CD1-CD1 4.4Å; I208-Y261 HydrophobicContact CD1-CE1 3.75Å; T228-Y261 HydrophobicContact CG2-CD1 4.27Å; K231-Y261 HydrophobicContact CB-CD1 4.47Å; K231-Y261 HydrophobicContact CB-CE1 4.27Å; K231-Y261 HydrophobicContact CB-CE2 4.4Å; K231-Y261 HydrophobicContact CD-CD1 4.27Å; K231-Y261 HydrophobicContact CD-CE1 3.47Å; K231-Y261 VanDerWaalsContact CD-CE1 3.47Å; K231-Y261 HydrophobicContact CG-CE1 4.49Å; L235-Y261 HydrophobicContact CD1-CD2 3.49Å; L235-Y261 VanDerWaalsContact CD1-CD2 3.49Å; L235-Y261 HydrophobicContact CD1-CE2 3.77Å; Q257-Y261 WeakPolarHBondContact O-CD2 3.49Å; Q257-Y261 PolarHBondContact O-N 2.88Å; M258-Y261 PolarHBondContact O-N 2.85Å; Y261-N263 VanDerWaalsContact C-N 3.3Å; Y261-N263 PolarHBondContact O-N 2.7Å; Y261-I264 HydrophobicContact CD1-CD1 3.9Å; Y261-I264 HydrophobicContact CE1-CD1 4.48Å; Y261-I264 WeakPolarHBondContact O-CB 3.3Å; Y261-I264 PolarHBondContact O-N 2.91Å; Y261-E265 PolarHBondContact O-N 2.97Å
262	A	92.9	Very high	93.6	Very high	23 Å²	23	48.5 Å²	48.5	19%	0.19	24%	0.237	C	C	.	.	H	α-helix	trans	-62.3	-38.5	172.9	0	0	0	0	0	111.7	L175 M258 Y260 E265 E266	L175-A262 HydrophobicContact CD2-CB 4.22Å; M258-A262 VanDerWaalsContact O-CB 3.28Å; M258-A262 WeakPolarHBondContact O-CB 3.24Å; M258-A262 PolarHBondContact O-N 3.02Å; Y260-A262 VanDerWaalsContact C-N 3.31Å; Y260-A262 PolarHBondContact O-N 3.47Å; A262-E265 PolarHBondContact O-N 2.87Å; A262-E266 PolarHBondContact O-N 3.48Å; A262-E266 VanDerWaalsContact O-N 3.13Å
263	N	93.4	Very high	93.7	Very high	83 Å²	83	49.3 Å²	49.3	44%	0.444	25%	0.249	S	C	.	.	H	α-helix	trans	-65.2	-39.3	173.5	-67.9	-21.2	0	0	0	111.9	K259 Y260 Y261 E265 E266 K267	K259-N263 VanDerWaalsContact O-CG 3.26Å; K259-N263 PolarHBondContact O-N 3.02Å; K259-N263 VanDerWaalsContact O-N 3.11Å; K259-N263 PolarHBondContact O-ND2 3.15Å; Y260-N263 WeakPolarHBondContact O-CB 3.36Å; Y260-N263 PolarHBondContact O-N 2.9Å; Y260-N263 VanDerWaalsContact O-N 3.14Å; Y261-N263 VanDerWaalsContact C-N 3.3Å; Y261-N263 PolarHBondContact O-N 2.7Å; N263-E265 VanDerWaalsContact C-N 3.34Å; N263-E266 PolarHBondContact O-N 2.65Å; N263-K267 WeakPolarHBondContact O-CG 3.25Å; N263-K267 PolarHBondContact O-N 3.08Å
264	I	95	Very high	93.8	Very high	2 Å²	2	50.5 Å²	50.5	1%	0.01	26%	0.258	C	S	.	.	H	α-helix	trans	-61.1	-45	172.8	-64.6	165.6	0	0	0	110.1	L205 I208 T228 Y260 Y261 E266 K267 V268	L205-I264 HydrophobicContact CD1-CD1 3.31Å; L205-I264 HydrophobicContact CD1-CG1 3.85Å; I208-I264 HydrophobicContact CB-CD1 4.22Å; I208-I264 HydrophobicContact CD1-CD1 4.12Å; I208-I264 HydrophobicContact CG2-CD1 3.73Å; I208-I264 HydrophobicContact CG2-CG1 4.33Å; I208-I264 HydrophobicContact CG2-CG2 3.69Å; T228-I264 HydrophobicContact CG2-CB 4.24Å; T228-I264 HydrophobicContact CG2-CG2 4.08Å; Y260-I264 WeakPolarHBondContact O-CG1 3.08Å; Y260-I264 PolarHBondContact O-N 2.87Å; Y261-I264 HydrophobicContact CD1-CD1 3.9Å; Y261-I264 HydrophobicContact CE1-CD1 4.48Å; Y261-I264 WeakPolarHBondContact O-CB 3.3Å; Y261-I264 PolarHBondContact O-N 2.91Å; I264-E266 VanDerWaalsContact C-N 3.26Å; I264-E266 PolarHBondContact O-N 2.99Å; I264-K267 CarbonylContact O-C 3.41Å; I264-K267 WeakPolarHBondContact O-CA 3.49Å; I264-K267 WeakPolarHBondContact O-CB 3.39Å; I264-K267 PolarHBondContact O-N 2.99Å; I264-V268 HydrophobicContact CG2-CG2 4.12Å; I264-V268 WeakPolarHBondContact O-CG2 3.43Å; I264-V268 PolarHBondContact O-N 2.77Å
265	E	94.8	Very high	93.5	Very high	43 Å²	43	53.6 Å²	53.6	20%	0.201	27%	0.271	C	S	.	.	H	α-helix	trans	-57.4	-40.3	178.9	-160.2	-160.3	-149.8	0	0	111.7	K229 L232 Y261 A262 N263 V268 K269	K229-E265 VanDerWaalsContact CE-OE1 3.28Å; K229-E265 WeakPolarHBondContact CE-OE1 3.11Å; L232-E265 HydrophobicContact CD1-CB 4.47Å; Y261-E265 PolarHBondContact O-N 2.97Å; A262-E265 PolarHBondContact O-N 2.87Å; N263-E265 VanDerWaalsContact C-N 3.34Å; E265-V268 PolarHBondContact O-N 3.25Å; E265-K269 WeakPolarHBondContact O-CG 3.49Å; E265-K269 PolarHBondContact O-N 2.89Å; E265-K269 IonicContact OE2-NZ 2.79Å; E265-K269 PolarHBondContact OE2-NZ 3.09Å
266	E	94.8	Very high	92.8	Very high	101 Å²	101	64 Å²	64	47%	0.472	32%	0.322	S	S	.	.	H	α-helix	trans	-67.5	-39.5	174.5	-65.3	-59.7	129.2	0	0	112.4	A262 N263 I264 K269 A270	A262-E266 PolarHBondContact O-N 3.48Å; A262-E266 VanDerWaalsContact O-N 3.13Å; N263-E266 PolarHBondContact O-N 2.65Å; I264-E266 VanDerWaalsContact C-N 3.26Å; I264-E266 PolarHBondContact O-N 2.99Å; E266-K269 PolarHBondContact O-N 3.03Å; E266-K269 IonicContact OE1-NZ 2.77Å; E266-K269 PolarHBondContact OE1-NZ 3.15Å; E266-A270 PolarHBondContact O-N 3.34Å
267	K	95.6	Very high	93	Very high	101 Å²	101	66 Å²	66	44%	0.439	33%	0.331	S	S	.	.	H	α-helix	trans	-63	-40.5	173.2	-69.6	-177.7	-179.2	-171	0	112.2	N209 L212 N263 I264 A270 K271	N209-K267 PolarHBondContact OD1-NZ 3.23Å; L212-K267 HydrophobicContact CD2-CB 3.64Å; L212-K267 HydrophobicContact CD2-CD 4.44Å; N263-K267 WeakPolarHBondContact O-CG 3.25Å; N263-K267 PolarHBondContact O-N 3.08Å; I264-K267 CarbonylContact O-C 3.41Å; I264-K267 WeakPolarHBondContact O-CA 3.49Å; I264-K267 WeakPolarHBondContact O-CB 3.39Å; I264-K267 PolarHBondContact O-N 2.99Å; K267-A270 PolarHBondContact O-N 3.32Å; K267-K271 WeakPolarHBondContact O-CB 3.24Å; K267-K271 PolarHBondContact O-N 2.76Å
268	V	96.3	Very high	93	Very high	7 Å²	7	66.4 Å²	66.4	4%	0.042	33%	0.334	C	S	.	.	H	α-helix	trans	-60.2	-47.8	175.1	167.7	0	0	0	0	110.2	L212 V221 I224 I264 E265 A270 K271 L272	L212-V268 HydrophobicContact CD1-CG2 3.87Å; L212-V268 HydrophobicContact CD2-CG2 4.06Å; V221-V268 HydrophobicContact CG1-CG1 3.9Å; I224-V268 HydrophobicContact CG2-CG2 4.14Å; I264-V268 HydrophobicContact CG2-CG2 4.12Å; I264-V268 WeakPolarHBondContact O-CG2 3.43Å; I264-V268 PolarHBondContact O-N 2.77Å; E265-V268 PolarHBondContact O-N 3.25Å; V268-A270 VanDerWaalsContact C-N 3.33Å; V268-A270 PolarHBondContact O-N 3.27Å; V268-K271 PolarHBondContact O-N 3.15Å; V268-L272 HydrophobicContact CG1-CD1 4.1Å; V268-L272 WeakPolarHBondContact O-CB 3.47Å; V268-L272 WeakPolarHBondContact O-CG 3.08Å; V268-L272 PolarHBondContact O-N 3.28Å
269	K	95.3	Very high	92.9	Very high	92 Å²	92	69.9 Å²	69.9	40%	0.4	35%	0.351	S	S	.	.	H	α-helix	trans	-59.7	-43.3	176.7	-70.7	169	-163.5	159.2	0	111.9	E265 E266 L272 S273	E265-K269 WeakPolarHBondContact O-CG 3.49Å; E265-K269 PolarHBondContact O-N 2.89Å; E265-K269 IonicContact OE2-NZ 2.79Å; E265-K269 PolarHBondContact OE2-NZ 3.09Å; E266-K269 PolarHBondContact O-N 3.03Å; E266-K269 IonicContact OE1-NZ 2.77Å; E266-K269 PolarHBondContact OE1-NZ 3.15Å; K269-L272 PolarHBondContact O-N 3.5Å; K269-S273 PolarHBondContact O-N 3.18Å; K269-S273 VanDerWaalsContact O-N 3.07Å
270	A	95.6	Very high	93	Very high	49 Å²	49	69.5 Å²	69.5	41%	0.405	35%	0.352	S	S	.	.	H	α-helix	trans	-62.8	-48.6	177.4	0	0	0	0	0	111.5	E266 K267 V268 L272 S273 D274	E266-A270 PolarHBondContact O-N 3.34Å; K267-A270 PolarHBondContact O-N 3.32Å; V268-A270 VanDerWaalsContact C-N 3.33Å; V268-A270 PolarHBondContact O-N 3.27Å; A270-L272 VanDerWaalsContact C-N 3.32Å; A270-L272 PolarHBondContact O-N 3Å; A270-S273 PolarHBondContact O-N 3.28Å; A270-S273 PolarHBondContact O-OG 3.43Å; A270-D274 PolarHBondContact O-N 3Å; A270-D274 VanDerWaalsContact O-N 3.16Å
271	K	94.3	Very high	93	Very high	41 Å²	41	68.6 Å²	68.6	18%	0.178	35%	0.354	C	S	.	.	H	α-helix	trans	-64.1	-36.9	179	-170.3	166.4	178.8	165.3	0	112.3	L212 E213 A215 V221 K267 V268 S273 D274 F275	L212-K271 HydrophobicContact CD1-CD 4.04Å; L212-K271 HydrophobicContact CG-CD 4.3Å; L212-K271 WeakPolarHBondContact O-CD 3.3Å; L212-K271 WeakPolarHBondContact O-CE 3.48Å; L212-K271 PolarHBondContact O-NZ 3.35Å; E213-K271 PolarHBondContact O-NZ 2.96Å; A215-K271 WeakPolarHBondContact O-CE 3.24Å; A215-K271 PolarHBondContact O-NZ 2.9Å; V221-K271 HydrophobicContact CG1-CB 4.34Å; V221-K271 HydrophobicContact CG2-CD 3.97Å; V221-K271 HydrophobicContact CG2-CG 4.11Å; K267-K271 WeakPolarHBondContact O-CB 3.24Å; K267-K271 PolarHBondContact O-N 2.76Å; V268-K271 PolarHBondContact O-N 3.15Å; K271-S273 VanDerWaalsContact C-N 3.31Å; K271-S273 PolarHBondContact O-N 3.31Å; K271-D274 WeakPolarHBondContact O-CB 3.4Å; K271-D274 PolarHBondContact O-N 3Å; K271-F275 HydrophobicContact CG-CE2 3.98Å; K271-F275 WeakPolarHBondContact O-CD2 3.38Å
272	L	94.4	Very high	92.9	Very high	40 Å²	40	72.4 Å²	72.4	21%	0.209	38%	0.375	C	S	.	.	H	α-helix	trans	-61.6	-38.8	171.9	-75.7	171.4	0	0	0	112.4	P218 V221 N222 V268 K269 A270 D274 F275	P218-L272 HydrophobicContact CB-CD2 4.3Å; V221-L272 HydrophobicContact CB-CD2 3.86Å; V221-L272 HydrophobicContact CB-CG 4.3Å; V221-L272 HydrophobicContact CG1-CD1 4.4Å; V221-L272 HydrophobicContact CG1-CD2 3.75Å; V221-L272 HydrophobicContact CG1-CG 3.61Å; N222-L272 WeakPolarHBondContact OD1-CD1 3.28Å; V268-L272 HydrophobicContact CG1-CD1 4.1Å; V268-L272 WeakPolarHBondContact O-CB 3.47Å; V268-L272 WeakPolarHBondContact O-CG 3.08Å; V268-L272 PolarHBondContact O-N 3.28Å; K269-L272 PolarHBondContact O-N 3.5Å; A270-L272 VanDerWaalsContact C-N 3.32Å; A270-L272 PolarHBondContact O-N 3Å; L272-D274 VanDerWaalsContact C-N 3.25Å; L272-D274 PolarHBondContact O-N 3.45Å; L272-F275 PolarHBondContact O-N 2.87Å
273	S	93.2	Very high	92.9	Very high	66 Å²	66	75.9 Å²	75.9	46%	0.462	39%	0.388	S	S	.	.	H	α-helix	trans	-68.1	-24	176.6	62.9	0	0	0	0	113.6	K269 A270 K271 F275 M276	K269-S273 PolarHBondContact O-N 3.18Å; K269-S273 VanDerWaalsContact O-N 3.07Å; A270-S273 PolarHBondContact O-N 3.28Å; A270-S273 PolarHBondContact O-OG 3.43Å; K271-S273 VanDerWaalsContact C-N 3.31Å; K271-S273 PolarHBondContact O-N 3.31Å; S273-F275 PolarHBondContact O-N 2.84Å; S273-M276 PolarHBondContact O-N 3.02Å
274	D	92.6	Very high	92.9	Very high	132 Å²	132	75.4 Å²	75.4	71%	0.706	38%	0.383	S	S	*	.	H	α-helix	trans	-71.6	-18.8	175.4	-62.9	-25.9	0	0	0	112.8	A270 K271 L272	A270-D274 PolarHBondContact O-N 3Å; A270-D274 VanDerWaalsContact O-N 3.16Å; K271-D274 WeakPolarHBondContact O-CB 3.4Å; K271-D274 PolarHBondContact O-N 3Å; L272-D274 VanDerWaalsContact C-N 3.25Å; L272-D274 PolarHBondContact O-N 3.45Å
275	F	87.4	Confident	92.7	Very high	87 Å²	87	81.5 Å²	81.5	38%	0.382	42%	0.415	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-7.8	175.7	-69.7	-72.4	0	0	0	114	Q216 P218 V221 K271 L272 S273	Q216-F275 WeakPolarHBondContact O-CE1 3.25Å; P218-F275 HydrophobicContact CB-CB 4.5Å; V221-F275 HydrophobicContact CG2-CE2 3.89Å; K271-F275 HydrophobicContact CG-CE2 3.98Å; K271-F275 WeakPolarHBondContact O-CD2 3.38Å; L272-F275 PolarHBondContact O-N 2.87Å; S273-F275 PolarHBondContact O-N 2.84Å
276	M	78.4	Confident	92.5	Very high	219 Å²	219	85 Å²	85	100%	1.079	43%	0.434	S	S	*	.			trans	-94.1	0	-178.4	-64.6	-173.4	74.7	0	0	112.2	S273	S273-M276 PolarHBondContact O-N 3.02Å

Retrieved 276 of 276 residues in 433.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).