A0A087X6W6_POEFO Loading...

Solute carrier organic anion transporter family member

AlphaFold DB , UniProt , Accession A0A087X6W6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 657 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M36.1Very low33.7Very low233 Ų233139.5 Ų139.5100%1.14886%0.855SS**  047.10-158179.4-78.400111.4
2V32.3Very low33.9Very low146 Ų146136.7 Ų136.789%0.88586%0.856SS**  trans-137.910.4170.5-1790000109.4
3A33.1Very low34Very low86 Ų86131.8 Ų131.871%0.71185%0.849SS**SBendtrans-104.1-8.4-175.100000114.3
4D31.9Very low34.8Very low143 Ų143139.1 Ų139.177%0.76585%0.851SS**SBendtrans-113.67.8-169.6-69-45.8000115.7
5I34.1Very low35.5Very low163 Ų163145.8 Ų145.884%0.83686%0.855SS**SBendtrans-96.93.9178.7-61.7178.1000113
6M34.6Very low36.6Very low185 Ų185151.4 Ų151.491%0.91186%0.857SS**SBendtrans-99.47.6178.9-70.5-1727400115.4
7N34.1Very low38.7Very low162 Ų162145.4 Ų145.487%0.86683%0.826SS**SBendtrans-112.513.9-175.1-93.4-7.4000116.1
8S33Very low41.1Very low118 Ų118141.6 Ų141.683%0.82581%0.808SS**  trans-14483.6174.5-174.30000112.2
9A30.6Very low43.4Very low102 Ų102136.8 Ų136.884%0.84378%0.778SS**  trans-158.4106.5153.600000108.5
10G30.5Very low45.5Very low71 Ų71138.4 Ų138.473%0.73277%0.77SS**  trans-67146.2176.900000113.3
11S40.7Very low47.6Very low126 Ų126133.9 Ų133.988%0.88175%0.748SS**SBendtrans41.476.7148.666.20000118.7
12A36Very low50.2Low105 Ų105123.1 Ų123.187%0.86870%0.695SS**SBendtrans-167.2124.1144.600000110.1
13G35.4Very low53.1Low74 Ų74122.2 Ų122.276%0.76368%0.679SS**  trans90.780.6171.500000114.6R15G13-R15 PolarHBondContact O-N 3.45Å
14R44.4Very low56Low234 Ų234120.1 Ų120.188%0.88366%0.658SS**  trans-64.483.1165.5-157.9-175.4-71.2-158.61107.8W16R14-W16 PolarHBondContact O-N 3.5Å
15R45.9Very low59Low239 Ų239113.3 Ų113.390%0.90262%0.621SS**  trans-58.2102.1-179.4-159.3173.9-174.8178.71.6107.4G13 S17G13-R15 PolarHBondContact O-N 3.45Å; R15-S17 PolarHBondContact O-N 2.69Å
16W53.8Low61.8Low236 Ų236105.9 Ų105.989%0.89458%0.584SS**  trans-60.888.8175.2-98.730.7000107.9R14 P18R14-W16 PolarHBondContact O-N 3.5Å; W16-P18 WeakPolarHBondContact O-CD 3.43Å
17S71.5Confident64.7Low48 Ų48102.2 Ų102.234%0.33657%0.567SS.*  trans-73.4117.9165.5172.20000106.7R15 F19 R20R15-S17 PolarHBondContact O-N 2.69Å; S17-F19 PolarHBondContact O-N 2.75Å; S17-F19 PolarHBondContact OG-N 2.68Å; S17-R20 PolarHBondContact O-N 3.32Å
18P81.7Confident67.7Low77 Ų7795.4 Ų95.450%0.553%0.532SS..G310 helixtrans-57.6-24.2177.923.2-32.7000111.8W16 R20 S21 V24W16-P18 WeakPolarHBondContact O-CD 3.43Å; P18-R20 PolarHBondContact O-N 2.89Å; P18-S21 WeakPolarHBondContact O-CB 3.5Å; P18-S21 PolarHBondContact O-N 3.41Å; P18-V24 WeakPolarHBondContact O-CB 3.41Å; P18-V24 WeakPolarHBondContact O-CG2 3.47Å
19F85.3Confident70.6Confident52 Ų5289.8 Ų89.823%0.22849%0.493CS..G310 helixtrans-74.30.1177.2-55.9-77.1000114.7S17 P259 F262 F263 P264 M267S17-F19 PolarHBondContact O-N 2.75Å; S17-F19 PolarHBondContact OG-N 2.68Å; F19-P259 HydrophobicContact CE1-CB 4.11Å; F19-F262 HydrophobicContact CB-CB 4.35Å; F19-F262 HydrophobicContact CD1-CB 3.84Å; F19-F262 HydrophobicContact CD2-CB 3.74Å; F19-F262 HydrophobicContact CD2-CG 4.44Å; F19-F262 HydrophobicContact CE1-CB 4.02Å; F19-F262 HydrophobicContact CE1-CD2 4.35Å; F19-F262 HydrophobicContact CE2-CB 3.92Å; F19-F262 HydrophobicContact CE2-CD2 4.46Å; F19-F262 HydrophobicContact CE2-CG 4.16Å; F19-F262 HydrophobicContact CG-CB 3.69Å; F19-F262 HydrophobicContact CZ-CB 4.05Å; F19-F262 HydrophobicContact CZ-CD2 4.08Å; F19-F262 HydrophobicContact CZ-CG 4.2Å; F19-F263 HydrophobicContact CB-CD1 4.03Å; F19-F263 HydrophobicContact CB-CE1 4.16Å; F19-F263 HydrophobicContact CD1-CD1 4.3Å; F19-F263 AromaticContact CD1-CE1 3.99Å; F19-F263 HydrophobicContact CD1-CE1 3.99Å; F19-F263 HydrophobicContact CD1-CE2 4.28Å; F19-F263 AromaticContact CD1-CZ 3.96Å; F19-F263 HydrophobicContact CD1-CZ 3.96Å; F19-F263 VanDerWaalsContact O-CD1 3.25Å; F19-F263 WeakPolarHBondContact O-CD1 3.23Å; F19-P264 WeakPolarHBondContact O-CD 3Å; F19-M267 WeakPolarHBondContact O-CE 3.06Å
20R85.4Confident73.7Confident167 Ų16785.2 Ų85.263%0.6346%0.455SS*.G310 helixtrans-95.97.1169.1-68.9-173.6178.3-162.20.2113.4S17 P18S17-R20 PolarHBondContact O-N 3.32Å; P18-R20 PolarHBondContact O-N 2.89Å
21S90.3Very high76.8Confident44 Ų4485 Ų8531%0.30844%0.436SS..  trans-101.8129.3176.8-179.40000111.9P18 K23 V24 F25 M267P18-S21 WeakPolarHBondContact O-CB 3.5Å; P18-S21 PolarHBondContact O-N 3.41Å; S21-K23 PolarHBondContact O-N 3.08Å; S21-K23 PolarHBondContact OG-N 3.35Å; S21-V24 PolarHBondContact O-N 2.85Å; S21-F25 PolarHBondContact O-N 2.97Å; S21-M267 VanDerWaalsContact C-SD 3.55Å
22I90.3Very high79.5Confident7 Ų779 Ų794%0.03639%0.394CS..Hα-helixtrans-63.5-33.3176.3-167.558.1000111.7V24 F25 V26 I180 A184 Y192 M267 E270I22-V24 VanDerWaalsContact C-N 3.31Å; I22-V24 PolarHBondContact O-N 2.83Å; I22-F25 HydrophobicContact CD1-CB 4.34Å; I22-F25 HydrophobicContact CD1-CD1 4.42Å; I22-F25 WeakPolarHBondContact O-CB 3.29Å; I22-F25 PolarHBondContact O-N 3.06Å; I22-F25 VanDerWaalsContact O-N 3.16Å; I22-V26 HydrophobicContact CG1-CG2 4.49Å; I22-V26 VanDerWaalsContact O-CG2 3.28Å; I22-V26 WeakPolarHBondContact O-CG2 3.49Å; I22-V26 PolarHBondContact O-N 3.48Å; I22-I180 HydrophobicContact CD1-CG1 4.41Å; I22-A184 HydrophobicContact CG1-CB 4.22Å; I22-Y192 HydrophobicContact CG1-CE2 4.35Å; I22-Y192 HydrophobicContact CG2-CE2 4.02Å; I22-M267 WeakPolarHBondContact CA-SD 3.44Å; I22-M267 HydrophobicContact CB-SD 3.82Å; I22-M267 HydrophobicContact CD1-SD 3.91Å; I22-M267 HydrophobicContact CG1-SD 4.48Å; I22-M267 PolarHBondContact N-SD 3.08Å; I22-E270 HydrophobicContact CG2-CB 4.17Å; I22-E270 HydrophobicContact CG2-CG 4.37Å
23K92.3Very high82.2Confident127 Ų12774 Ų7455%0.55235%0.353SS*.Hα-helixtrans-61.5-40.3177.7-62176.2-175.3175.30111.4S21 V26 L27 Y192 E270S21-K23 PolarHBondContact O-N 3.08Å; S21-K23 PolarHBondContact OG-N 3.35Å; K23-V26 PolarHBondContact O-N 3.35Å; K23-L27 PolarHBondContact O-N 3.26Å; K23-Y192 WeakPolarHBondContact CG-OH 3.49Å; K23-E270 WeakPolarHBondContact CE-OE1 3.14Å
24V94.1Very high85.1Confident42 Ų4271.3 Ų71.326%0.25532%0.321SS..Hα-helixtrans-69.1-40.8176.1178.50000110.6P18 S21 I22 V26 L27 C28 F263P18-V24 WeakPolarHBondContact O-CB 3.41Å; P18-V24 WeakPolarHBondContact O-CG2 3.47Å; S21-V24 PolarHBondContact O-N 2.85Å; I22-V24 VanDerWaalsContact C-N 3.31Å; I22-V24 PolarHBondContact O-N 2.83Å; V24-V26 PolarHBondContact O-N 3.01Å; V24-L27 PolarHBondContact O-N 3.39Å; V24-C28 WeakPolarHBondContact O-CB 3.41Å; V24-C28 PolarHBondContact O-N 3.45Å; V24-C28 PolarHBondContact O-SG 3.25Å; V24-C28 VanDerWaalsContact O-SG 3.35Å; V24-F263 HydrophobicContact CG1-CE1 4.46Å; V24-F263 HydrophobicContact CG1-CZ 4.16Å
25F94.7Very high87.5Confident0 Ų060.1 Ų60.10%028%0.279CS..Hα-helixtrans-59.6-45.7173.6-176.6-88.5000111.9S21 I22 L27 C28 H29 P89 I92 Y179 I180 Y260 F263 M267S21-F25 PolarHBondContact O-N 2.97Å; I22-F25 HydrophobicContact CD1-CB 4.34Å; I22-F25 HydrophobicContact CD1-CD1 4.42Å; I22-F25 WeakPolarHBondContact O-CB 3.29Å; I22-F25 PolarHBondContact O-N 3.06Å; I22-F25 VanDerWaalsContact O-N 3.16Å; F25-L27 VanDerWaalsContact C-N 3.34Å; F25-L27 PolarHBondContact O-N 3.03Å; F25-C28 PolarHBondContact O-N 3.22Å; F25-H29 HydrophobicContact CD1-CB 4.41Å; F25-H29 HydrophobicContact CE1-CB 4.17Å; F25-H29 WeakPolarHBondContact O-CB 3.44Å; F25-H29 PolarHBondContact O-N 3.5Å; F25-P89 HydrophobicContact CE2-CG 4.33Å; F25-I92 HydrophobicContact CZ-CD1 4.11Å; F25-Y179 AromaticContact CD1-CD1 3.79Å; F25-Y179 HydrophobicContact CD1-CD1 3.79Å; F25-Y179 HydrophobicContact CD1-CE1 4.31Å; F25-Y179 AromaticContact CD2-CD1 3.87Å; F25-Y179 HydrophobicContact CD2-CD1 3.87Å; F25-Y179 AromaticContact CD2-CE1 3.76Å; F25-Y179 HydrophobicContact CD2-CE1 3.76Å; F25-Y179 AromaticContact CE1-CD1 3.56Å; F25-Y179 HydrophobicContact CE1-CD1 3.56Å; F25-Y179 HydrophobicContact CE1-CE1 4.4Å; F25-Y179 HydrophobicContact CE1-CG 4.17Å; F25-Y179 AromaticContact CE2-CD1 3.62Å; F25-Y179 HydrophobicContact CE2-CD1 3.62Å; F25-Y179 AromaticContact CE2-CE1 3.83Å; F25-Y179 HydrophobicContact CE2-CE1 3.83Å; F25-Y179 HydrophobicContact CE2-CG 4.19Å; F25-Y179 AromaticContact CG-CD1 3.95Å; F25-Y179 HydrophobicContact CG-CD1 3.95Å; F25-Y179 HydrophobicContact CG-CE1 4Å; F25-Y179 AromaticContact CZ-CD1 3.45Å; F25-Y179 HydrophobicContact CZ-CD1 3.45Å; F25-Y179 VanDerWaalsContact CZ-CD1 3.45Å; F25-Y179 HydrophobicContact CZ-CE1 4.16Å; F25-Y179 AromaticContact CZ-CG 3.82Å; F25-Y179 HydrophobicContact CZ-CG 3.82Å; F25-I180 HydrophobicContact CD1-CD1 4.18Å; F25-I180 HydrophobicContact CD1-CG1 3.73Å; F25-I180 HydrophobicContact CE1-CD1 4.11Å; F25-I180 HydrophobicContact CE1-CG1 3.78Å; F25-Y260 HydrophobicContact CE2-CD1 4.44Å; F25-Y260 AromaticContact CE2-CE1 3.71Å; F25-Y260 HydrophobicContact CE2-CE1 3.71Å; F25-Y260 HydrophobicContact CZ-CE1 4.12Å; F25-F263 HydrophobicContact CB-CD1 4.4Å; F25-F263 HydrophobicContact CB-CE1 3.8Å; F25-F263 HydrophobicContact CB-CZ 3.99Å; F25-F263 AromaticContact CD2-CD1 3.94Å; F25-F263 HydrophobicContact CD2-CD1 3.94Å; F25-F263 AromaticContact CD2-CD2 3.92Å; F25-F263 HydrophobicContact CD2-CD2 3.92Å; F25-F263 HydrophobicContact CD2-CE1 4.02Å; F25-F263 HydrophobicContact CD2-CE2 4Å; F25-F263 AromaticContact CD2-CG 3.92Å; F25-F263 HydrophobicContact CD2-CG 3.92Å; F25-F263 HydrophobicContact CD2-CZ 4.06Å; F25-F263 HydrophobicContact CE2-CD2 4.4Å; F25-F263 HydrophobicContact CG-CE1 4.43Å; F25-F263 HydrophobicContact CG-CZ 4.49Å; F25-M267 HydrophobicContact CB-CE 4.2Å
26V94.1Very high89.8Confident8 Ų849.5 Ų49.55%0.04824%0.24CC..Hα-helixtrans-60.3-43.3177.7173.40000111.1I22 K23 V24 S30 I180 Y192I22-V26 HydrophobicContact CG1-CG2 4.49Å; I22-V26 VanDerWaalsContact O-CG2 3.28Å; I22-V26 WeakPolarHBondContact O-CG2 3.49Å; I22-V26 PolarHBondContact O-N 3.48Å; K23-V26 PolarHBondContact O-N 3.35Å; V24-V26 PolarHBondContact O-N 3.01Å; V26-S30 WeakPolarHBondContact O-CB 3.44Å; V26-S30 PolarHBondContact O-N 2.79Å; V26-S30 PolarHBondContact O-OG 2.95Å; V26-I180 HydrophobicContact CG2-CD1 3.85Å; V26-I180 HydrophobicContact CG2-CG1 3.92Å; V26-I180 HydrophobicContact CG2-CG2 4.4Å; V26-Y192 HydrophobicContact CG1-CD1 4.22Å; V26-Y192 HydrophobicContact CG1-CG 4.27Å; V26-Y192 HydrophobicContact CG2-CD1 4.24Å; V26-Y192 HydrophobicContact CG2-CD2 3.78Å; V26-Y192 HydrophobicContact CG2-CE2 4.39Å; V26-Y192 HydrophobicContact CG2-CG 3.69Å
27L95.1Very high91.7Very high108 Ų10839.8 Ų39.857%0.56521%0.205SC*.Hα-helixtrans-62.3-52.8176.1178.364.9000111.7K23 V24 F25 H29 S30 L31K23-L27 PolarHBondContact O-N 3.26Å; V24-L27 PolarHBondContact O-N 3.39Å; F25-L27 VanDerWaalsContact C-N 3.34Å; F25-L27 PolarHBondContact O-N 3.03Å; L27-H29 VanDerWaalsContact C-N 3.29Å; L27-H29 PolarHBondContact O-N 2.95Å; L27-S30 WeakPolarHBondContact O-CB 3.3Å; L27-S30 PolarHBondContact O-N 3.15Å; L27-L31 HydrophobicContact CD1-CD1 4.41Å; L27-L31 HydrophobicContact CG-CD1 4.4Å; L27-L31 WeakPolarHBondContact O-CG 3.29Å; L27-L31 PolarHBondContact O-N 3.44Å
28C95.9Very high92.9Very high19 Ų1938.2 Ų38.213%0.12819%0.193CC..Hα-helixtrans-59.7-41.9178.8-690000111.6V24 F25 L31 L32 P259 F263V24-C28 WeakPolarHBondContact O-CB 3.41Å; V24-C28 PolarHBondContact O-N 3.45Å; V24-C28 PolarHBondContact O-SG 3.25Å; V24-C28 VanDerWaalsContact O-SG 3.35Å; F25-C28 PolarHBondContact O-N 3.22Å; C28-L31 PolarHBondContact O-N 3.24Å; C28-L32 WeakPolarHBondContact O-CB 3.4Å; C28-L32 PolarHBondContact O-N 3.33Å; C28-P259 HydrophobicContact CB-CB 4.28Å; C28-F263 HydrophobicContact CB-CE2 4.04Å; C28-F263 HydrophobicContact CB-CZ 4.22Å
29H95.8Very high93.6Very high0 Ų034.6 Ų34.60%017%0.169CC..Hα-helixtrans-69.3-38.8-179.8-165.546.5000112.5F25 L27 L31 L32 Q33 I172 G176 L196 Y260F25-H29 HydrophobicContact CD1-CB 4.41Å; F25-H29 HydrophobicContact CE1-CB 4.17Å; F25-H29 WeakPolarHBondContact O-CB 3.44Å; F25-H29 PolarHBondContact O-N 3.5Å; L27-H29 VanDerWaalsContact C-N 3.29Å; L27-H29 PolarHBondContact O-N 2.95Å; H29-L31 VanDerWaalsContact C-N 3.35Å; H29-L31 PolarHBondContact O-N 3.28Å; H29-L32 PolarHBondContact O-N 3.39Å; H29-Q33 VanDerWaalsContact O-CB 3.3Å; H29-Q33 WeakPolarHBondContact O-CB 3.19Å; H29-Q33 PolarHBondContact O-N 3.43Å; H29-I172 PolarHBondContact CE1-O 3.13Å; H29-G176 WeakPolarHBondContact NE2-CA 3.24Å; H29-L196 WeakPolarHBondContact CD2-CD2 3.07Å; H29-Y260 WeakPolarHBondContact CA-OH 3.35Å; H29-Y260 WeakPolarHBondContact CB-OH 3.31Å; H29-Y260 VanDerWaalsContact CG-OH 3.3Å; H29-Y260 PolarHBondContact ND1-OH 2.6Å
30S94.7Very high93.9Very high6 Ų633 Ų334%0.04216%0.164CC..Hα-helixtrans-59.8-44172.9-66.20000112V26 L27 L34V26-S30 WeakPolarHBondContact O-CB 3.44Å; V26-S30 PolarHBondContact O-N 2.79Å; V26-S30 PolarHBondContact O-OG 2.95Å; L27-S30 WeakPolarHBondContact O-CB 3.3Å; L27-S30 PolarHBondContact O-N 3.15Å; S30-L34 WeakPolarHBondContact O-CB 3.12Å; S30-L34 PolarHBondContact O-N 2.8Å
31L95.8Very high94.4Very high66 Ų6625.1 Ų25.135%0.34614%0.135SC..Hα-helixtrans-67.2-42.7176.7-68.6173.3000112.1L27 C28 H29 L34 A35 T256L27-L31 HydrophobicContact CD1-CD1 4.41Å; L27-L31 HydrophobicContact CG-CD1 4.4Å; L27-L31 WeakPolarHBondContact O-CG 3.29Å; L27-L31 PolarHBondContact O-N 3.44Å; C28-L31 PolarHBondContact O-N 3.24Å; H29-L31 VanDerWaalsContact C-N 3.35Å; H29-L31 PolarHBondContact O-N 3.28Å; L31-L34 PolarHBondContact O-N 3.04Å; L31-A35 WeakPolarHBondContact O-CB 3.35Å; L31-A35 PolarHBondContact O-N 3.06Å; L31-T256 HydrophobicContact CB-CG2 3.84Å
32L96.4Very high94.7Very high0 Ų023 Ų230%012%0.12CC..Hα-helixtrans-62-44.2176.3175.462.1000111.7C28 H29 L34 A35 Q36 I92 A96 I172 L253 Y260C28-L32 WeakPolarHBondContact O-CB 3.4Å; C28-L32 PolarHBondContact O-N 3.33Å; H29-L32 PolarHBondContact O-N 3.39Å; L32-L34 VanDerWaalsContact C-N 3.33Å; L32-L34 PolarHBondContact O-N 3Å; L32-A35 PolarHBondContact O-N 3.09Å; L32-Q36 WeakPolarHBondContact O-CB 3.17Å; L32-Q36 PolarHBondContact O-N 3.32Å; L32-I92 HydrophobicContact CD2-CG2 3.45Å; L32-I92 VanDerWaalsContact CD2-CG2 3.45Å; L32-A96 HydrophobicContact CD1-CB 3.56Å; L32-A96 HydrophobicContact CD2-CB 4.05Å; L32-A96 HydrophobicContact CG-CB 4.43Å; L32-I172 HydrophobicContact CD2-CG2 4Å; L32-I172 HydrophobicContact CG-CG2 4.18Å; L32-L253 HydrophobicContact CD1-CD2 3.97Å; L32-Y260 HydrophobicContact CB-CE2 4.27Å; L32-Y260 HydrophobicContact CD2-CD2 4.14Å; L32-Y260 HydrophobicContact CD2-CE2 3.44Å; L32-Y260 VanDerWaalsContact CD2-CE2 3.44Å; L32-Y260 HydrophobicContact CG-CE2 4.44Å
33Q94.3Very high94.9Very high1 Ų122.8 Ų22.81%0.00512%0.119CC..Hα-helixtrans-63.7-41178.3-169.568.355.500111.3H29 L37 L196 T200H29-Q33 VanDerWaalsContact O-CB 3.3Å; H29-Q33 WeakPolarHBondContact O-CB 3.19Å; H29-Q33 PolarHBondContact O-N 3.43Å; Q33-L37 HydrophobicContact CG-CD1 4.07Å; Q33-L37 WeakPolarHBondContact O-CB 3.39Å; Q33-L37 WeakPolarHBondContact O-CG 3.33Å; Q33-L37 PolarHBondContact O-N 2.76Å; Q33-L37 VanDerWaalsContact O-N 3.09Å; Q33-L196 HydrophobicContact CB-CD2 4.3Å; Q33-L196 HydrophobicContact CG-CD2 4.33Å; Q33-T200 HydrophobicContact CG-CG2 3.62Å
34L94.7Very high95.1Very high16 Ų1618.9 Ų18.98%0.08410%0.102CC..Hα-helixtrans-61.5-47.4173.2-177.4154.8000111.1S30 L31 L32 Q36 L37 L38 M199 I202 L206 F252S30-L34 WeakPolarHBondContact O-CB 3.12Å; S30-L34 PolarHBondContact O-N 2.8Å; L31-L34 PolarHBondContact O-N 3.04Å; L32-L34 VanDerWaalsContact C-N 3.33Å; L32-L34 PolarHBondContact O-N 3Å; L34-Q36 PolarHBondContact O-N 3.2Å; L34-L37 PolarHBondContact O-N 2.78Å; L34-L38 HydrophobicContact CD2-CD1 4.47Å; L34-L38 VanDerWaalsContact O-CB 3.23Å; L34-L38 WeakPolarHBondContact O-CB 3.38Å; L34-L38 PolarHBondContact O-N 2.86Å; L34-M199 HydrophobicContact CB-CE 3.98Å; L34-M199 HydrophobicContact CD1-CE 3.26Å; L34-M199 HydrophobicContact CD1-SD 4.25Å; L34-M199 HydrophobicContact CG-CE 4.26Å; L34-I202 HydrophobicContact CD1-CG2 3.98Å; L34-L206 HydrophobicContact CD1-CD1 3.81Å; L34-L206 HydrophobicContact CD2-CD1 3.89Å; L34-L206 HydrophobicContact CG-CD1 4.12Å; L34-F252 HydrophobicContact CD2-CE1 3.55Å; L34-F252 HydrophobicContact CD2-CZ 4.14Å
35A95.4Very high95.2Very high0 Ų017 Ų170%09%0.091CC..Hα-helixtrans-59.4-44.7179.200000112.2L31 L32 L38 V39 F252 L253 T256L31-A35 WeakPolarHBondContact O-CB 3.35Å; L31-A35 PolarHBondContact O-N 3.06Å; L32-A35 PolarHBondContact O-N 3.09Å; A35-L38 WeakPolarHBondContact O-CB 3.41Å; A35-L38 PolarHBondContact O-N 3.35Å; A35-V39 PolarHBondContact O-N 3.15Å; A35-F252 HydrophobicContact CB-CD1 3.35Å; A35-F252 HydrophobicContact CB-CE1 3.43Å; A35-F252 VanDerWaalsContact CB-CE1 3.43Å; A35-F252 HydrophobicContact CB-CG 4.2Å; A35-F252 HydrophobicContact CB-CZ 4.34Å; A35-L253 HydrophobicContact CB-CD2 3.69Å; A35-L253 HydrophobicContact CB-CG 3.9Å; A35-T256 HydrophobicContact CB-CG2 4.49Å
36Q95.2Very high95.2Very high16 Ų1617 Ų178%0.0759%0.091CC..Hα-helixtrans-64.9-44.5179.4178.7-87-42.900112.2L32 L34 L38 V39 A169 I172 L253L32-Q36 WeakPolarHBondContact O-CB 3.17Å; L32-Q36 PolarHBondContact O-N 3.32Å; L34-Q36 PolarHBondContact O-N 3.2Å; Q36-L38 VanDerWaalsContact C-N 3.34Å; Q36-V39 PolarHBondContact O-N 3.32Å; Q36-A169 HydrophobicContact CG-CB 4.18Å; Q36-I172 HydrophobicContact CB-CD1 4.39Å; Q36-I172 HydrophobicContact CG-CD1 4.13Å; Q36-L253 HydrophobicContact CB-CD2 4.09Å
37L93.9Very high95.3Very high31 Ų3116.9 Ų16.916%0.1629%0.09CC..Hα-helixtrans-76.4-24.5-179.2-66.6169000112.8Q33 L34 V39 S40 G41 T200 P204Q33-L37 HydrophobicContact CG-CD1 4.07Å; Q33-L37 WeakPolarHBondContact O-CB 3.39Å; Q33-L37 WeakPolarHBondContact O-CG 3.33Å; Q33-L37 PolarHBondContact O-N 2.76Å; Q33-L37 VanDerWaalsContact O-N 3.09Å; L34-L37 PolarHBondContact O-N 2.78Å; L37-V39 VanDerWaalsContact C-N 3.34Å; L37-S40 PolarHBondContact O-N 3.28Å; L37-G41 PolarHBondContact O-N 3.32Å; L37-T200 HydrophobicContact CD1-CG2 3.85Å; L37-T200 WeakPolarHBondContact CD1-O 3Å; L37-P204 HydrophobicContact CB-CG 4.21Å
38L95.8Very high95.2Very high16 Ų1612 Ų128%0.0847%0.065CC..Hα-helixtrans-59.2-43.9169.7-177.5156.1000111L34 A35 Q36 S40 G41 Y42 G203 L206 A249L34-L38 HydrophobicContact CD2-CD1 4.47Å; L34-L38 VanDerWaalsContact O-CB 3.23Å; L34-L38 WeakPolarHBondContact O-CB 3.38Å; L34-L38 PolarHBondContact O-N 2.86Å; A35-L38 WeakPolarHBondContact O-CB 3.41Å; A35-L38 PolarHBondContact O-N 3.35Å; Q36-L38 VanDerWaalsContact C-N 3.34Å; L38-S40 VanDerWaalsContact C-N 3.3Å; L38-S40 PolarHBondContact O-N 3.39Å; L38-G41 PolarHBondContact O-N 3.42Å; L38-Y42 WeakPolarHBondContact O-CB 3.11Å; L38-Y42 PolarHBondContact O-N 2.84Å; L38-G203 WeakPolarHBondContact CA-O 3.28Å; L38-L206 HydrophobicContact CD1-CB 4.05Å; L38-A249 HydrophobicContact CD2-CB 3.56Å
39V96.4Very high95.1Very high0 Ų011.1 Ų11.10%06%0.059CC..Hα-helixtrans-57.9-43.4175.4178.20000111.3A35 Q36 L37 Y42 M43 L165 F246 A249 L253A35-V39 PolarHBondContact O-N 3.15Å; Q36-V39 PolarHBondContact O-N 3.32Å; L37-V39 VanDerWaalsContact C-N 3.34Å; V39-Y42 PolarHBondContact O-N 2.97Å; V39-M43 PolarHBondContact O-N 3.08Å; V39-L165 HydrophobicContact CG1-CD1 4.15Å; V39-L165 HydrophobicContact CG1-CD2 3.7Å; V39-F246 HydrophobicContact CG1-CD1 4.41Å; V39-F246 HydrophobicContact CG1-CE1 4.36Å; V39-A249 HydrophobicContact CG2-CB 3.62Å; V39-L253 HydrophobicContact CG2-CD1 3.51Å; V39-L253 HydrophobicContact CG2-CG 4.43Å
40S92.4Very high95Very high19 Ų1911.3 Ų11.313%0.1336%0.06CC..Hα-helixtrans-65.3-42.8178.5-174.30000112.2L37 L38 M43 K44L37-S40 PolarHBondContact O-N 3.28Å; L38-S40 VanDerWaalsContact C-N 3.3Å; L38-S40 PolarHBondContact O-N 3.39Å; S40-M43 PolarHBondContact O-N 3.29Å; S40-K44 PolarHBondContact O-N 3.17Å
41G94.3Very high94.9Very high1 Ų111.2 Ų11.21%0.016%0.059CC..Hα-helixtrans-64.4-41.3174.700000112.8L37 L38 K44 S45L37-G41 PolarHBondContact O-N 3.32Å; L38-G41 PolarHBondContact O-N 3.42Å; G41-K44 PolarHBondContact O-N 3Å; G41-S45 PolarHBondContact O-N 3.33Å
42Y97Very high94.6Very high0 Ų09.7 Ų9.70%05%0.049CC..Hα-helixtrans-65.8-38.6177.6-176.7-101.3000112.5L38 V39 K44 S45 S46 T210 L214 M215 A241 W242 G245 F246L38-Y42 WeakPolarHBondContact O-CB 3.11Å; L38-Y42 PolarHBondContact O-N 2.84Å; V39-Y42 PolarHBondContact O-N 2.97Å; Y42-K44 VanDerWaalsContact C-N 3.33Å; Y42-K44 PolarHBondContact O-N 2.76Å; Y42-S45 WeakPolarHBondContact CA-OG 3.28Å; Y42-S45 PolarHBondContact O-N 3.05Å; Y42-S45 PolarHBondContact O-OG 3.44Å; Y42-S46 WeakPolarHBondContact O-CB 3.45Å; Y42-S46 PolarHBondContact O-N 3.48Å; Y42-S46 VanDerWaalsContact O-N 3.14Å; Y42-S46 PolarHBondContact O-OG 3.13Å; Y42-T210 HydrophobicContact CD2-CG2 4.32Å; Y42-L214 HydrophobicContact CE2-CD1 4.08Å; Y42-M215 HydrophobicContact CE2-CE 4.29Å; Y42-A241 PolarHBondContact OH-O 2.95Å; Y42-W242 WeakPolarHBondContact CE1-O 3.41Å; Y42-W242 VanDerWaalsContact OH-C 3.28Å; Y42-W242 WeakPolarHBondContact OH-CA 3.43Å; Y42-W242 PolarHBondContact OH-O 2.92Å; Y42-G245 VanDerWaalsContact CE1-CA 3.5Å; Y42-G245 WeakPolarHBondContact OH-CA 3.28Å; Y42-G245 PolarHBondContact OH-N 3.06Å; Y42-F246 AromaticContact CD1-CD1 3.94Å; Y42-F246 HydrophobicContact CD1-CD1 3.94Å; Y42-F246 HydrophobicContact CD1-CD2 4.35Å; Y42-F246 AromaticContact CD1-CE1 3.79Å; Y42-F246 HydrophobicContact CD1-CE1 3.79Å; Y42-F246 HydrophobicContact CD1-CE2 4.22Å; Y42-F246 HydrophobicContact CD1-CG 4.19Å; Y42-F246 AromaticContact CD1-CZ 3.92Å; Y42-F246 HydrophobicContact CD1-CZ 3.92Å; Y42-F246 HydrophobicContact CE1-CD1 4.26Å; Y42-F246 AromaticContact CE1-CD2 3.89Å; Y42-F246 HydrophobicContact CE1-CD2 3.89Å; Y42-F246 HydrophobicContact CE1-CE1 4.29Å; Y42-F246 AromaticContact CE1-CE2 3.92Å; Y42-F246 HydrophobicContact CE1-CE2 3.92Å; Y42-F246 HydrophobicContact CE1-CG 4.04Å; Y42-F246 HydrophobicContact CE1-CZ 4.11Å
43M95.7Very high94.3Very high3 Ų310 Ų102%0.0155%0.05CC..Hα-helixtrans-56.8-49.2173.517859.6-176.900111.1V39 S40 S45 S46 I47 I50 L64 M106 Q162 F246V39-M43 PolarHBondContact O-N 3.08Å; S40-M43 PolarHBondContact O-N 3.29Å; M43-S45 VanDerWaalsContact C-N 3.34Å; M43-S45 PolarHBondContact O-N 2.65Å; M43-S46 PolarHBondContact O-N 3.49Å; M43-S46 VanDerWaalsContact O-N 3.14Å; M43-I47 PolarHBondContact O-N 2.8Å; M43-I50 HydrophobicContact CE-CD1 4.22Å; M43-I50 HydrophobicContact SD-CD1 4.18Å; M43-L64 HydrophobicContact CE-CD1 4.12Å; M43-L64 HydrophobicContact CE-CD2 3.37Å; M43-L64 HydrophobicContact CE-CG 3.4Å; M43-M106 HydrophobicContact CE-CE 3.7Å; M43-M106 HydrophobicContact SD-CE 3.42Å; M43-M106 WeakPolarHBondContact SD-CE 3.43Å; M43-Q162 VanDerWaalsContact CG-NE2 3.31Å; M43-F246 HydrophobicContact CB-CE1 4.36Å; M43-F246 HydrophobicContact CB-CZ 4.29Å; M43-F246 HydrophobicContact SD-CE1 4.39Å; M43-F246 HydrophobicContact SD-CZ 3.63Å
44K95.1Very high94Very high44 Ų4410.6 Ų10.619%0.1915%0.052CC..Hα-helixtrans-63.3-39.2-179.6-68.2173.4-176.4175.10112.3S40 G41 Y42 S46 I47 F208 A334S40-K44 PolarHBondContact O-N 3.17Å; G41-K44 PolarHBondContact O-N 3Å; Y42-K44 VanDerWaalsContact C-N 3.33Å; Y42-K44 PolarHBondContact O-N 2.76Å; K44-S46 PolarHBondContact O-N 3.47Å; K44-I47 PolarHBondContact O-N 3.1Å; K44-F208 HydrophobicContact CB-CE1 4.41Å; K44-F208 HydrophobicContact CB-CZ 3.8Å; K44-A334 HydrophobicContact CD-CB 4.46Å
45S95.9Very high93.7Very high2 Ų210.6 Ų10.61%0.0146%0.056CC..Hα-helixtrans-68.9-17.4177.375.30000113.9G41 Y42 M43 G211 N353G41-S45 PolarHBondContact O-N 3.33Å; Y42-S45 WeakPolarHBondContact CA-OG 3.28Å; Y42-S45 PolarHBondContact O-N 3.05Å; Y42-S45 PolarHBondContact O-OG 3.44Å; M43-S45 VanDerWaalsContact C-N 3.34Å; M43-S45 PolarHBondContact O-N 2.65Å; S45-G211 WeakPolarHBondContact OG-CA 3.41Å; S45-N353 WeakPolarHBondContact CA-OD1 3.45Å; S45-N353 WeakPolarHBondContact CB-OD1 3.41Å; S45-N353 PolarHBondContact O-ND2 3.04Å
46S96.2Very high93.5Very high0 Ų011.1 Ų11.10%06%0.059CC..THydrogen-bonded Turntrans-96.8-7.2-177.2-56.40000114.3Y42 M43 K44 S48 T49 I50 M215Y42-S46 WeakPolarHBondContact O-CB 3.45Å; Y42-S46 PolarHBondContact O-N 3.48Å; Y42-S46 VanDerWaalsContact O-N 3.14Å; Y42-S46 PolarHBondContact O-OG 3.13Å; M43-S46 PolarHBondContact O-N 3.49Å; M43-S46 VanDerWaalsContact O-N 3.14Å; K44-S46 PolarHBondContact O-N 3.47Å; S46-S48 PolarHBondContact O-N 3.07Å; S46-T49 WeakPolarHBondContact O-CB 3.26Å; S46-T49 PolarHBondContact O-N 3.46Å; S46-T49 VanDerWaalsContact O-N 3.13Å; S46-I50 WeakPolarHBondContact O-CG1 3.24Å; S46-I50 PolarHBondContact O-N 2.84Å; S46-M215 WeakPolarHBondContact OG-CE 3.4Å
47I94.9Very high93.4Very high6 Ų611.4 Ų11.43%0.0316%0.062CC..Hα-helixtrans-56.6-50.8-170.4-76.1171.7000112.9M43 K44 T49 I50 E51 A65 T335 F336M43-I47 PolarHBondContact O-N 2.8Å; K44-I47 PolarHBondContact O-N 3.1Å; I47-T49 PolarHBondContact O-N 2.99Å; I47-T49 VanDerWaalsContact O-N 3.16Å; I47-I50 PolarHBondContact O-N 3.22Å; I47-E51 HydrophobicContact CG2-CG 4.24Å; I47-E51 WeakPolarHBondContact CG2-OE1 3.36Å; I47-E51 WeakPolarHBondContact O-CB 3.46Å; I47-E51 VanDerWaalsContact O-CG 3.3Å; I47-E51 WeakPolarHBondContact O-CG 3.27Å; I47-E51 PolarHBondContact O-N 3.41Å; I47-A65 HydrophobicContact CD1-CB 3.79Å; I47-T335 HydrophobicContact CD1-CG2 3.22Å; I47-F336 HydrophobicContact CG2-CE1 3.9Å
48S92.8Very high93.5Very high7 Ų710 Ų105%0.0496%0.055CC..Hα-helixtrans-63.1-27.6-176.564.30000112.5S46 R52 E342S46-S48 PolarHBondContact O-N 3.07Å; S48-R52 WeakPolarHBondContact O-CD 3.37Å; S48-R52 VanDerWaalsContact O-CG 3.22Å; S48-R52 WeakPolarHBondContact O-CG 3.49Å; S48-R52 PolarHBondContact O-N 2.94Å; S48-E342 WeakPolarHBondContact CB-OE2 3.34Å; S48-E342 PolarHBondContact OG-OE2 3.29Å
49T94.1Very high93.5Very high0 Ų013.2 Ų13.20%07%0.07CC..Hα-helixtrans-76.4-44.7177.1-60.60000111.8S46 I47 E51 R52 R53 M215 V239 G240 W242S46-T49 WeakPolarHBondContact O-CB 3.26Å; S46-T49 PolarHBondContact O-N 3.46Å; S46-T49 VanDerWaalsContact O-N 3.13Å; I47-T49 PolarHBondContact O-N 2.99Å; I47-T49 VanDerWaalsContact O-N 3.16Å; T49-E51 VanDerWaalsContact C-N 3.31Å; T49-E51 PolarHBondContact O-N 3.44Å; T49-R52 PolarHBondContact O-N 3.13Å; T49-R53 PolarHBondContact O-N 2.9Å; T49-M215 HydrophobicContact CG2-SD 4.13Å; T49-V239 HydrophobicContact CG2-CB 4.25Å; T49-V239 HydrophobicContact CG2-CG1 3.33Å; T49-G240 WeakPolarHBondContact CG2-O 3.33Å; T49-W242 HydrophobicContact CG2-CB 3.98Å; T49-W242 HydrophobicContact CG2-CG 4.15Å
50I93.8Very high93.4Very high3 Ų317.7 Ų17.72%0.0159%0.089CC..Hα-helixtrans-62.5-40.9176-65.3171.2000110.2M43 S46 I47 R53 Y54 L56 L158 W242M43-I50 HydrophobicContact CE-CD1 4.22Å; M43-I50 HydrophobicContact SD-CD1 4.18Å; S46-I50 WeakPolarHBondContact O-CG1 3.24Å; S46-I50 PolarHBondContact O-N 2.84Å; I47-I50 PolarHBondContact O-N 3.22Å; I50-R53 PolarHBondContact O-N 2.88Å; I50-Y54 HydrophobicContact CG2-CD2 4.05Å; I50-Y54 PolarHBondContact O-N 3.01Å; I50-L56 HydrophobicContact CG2-CD1 3.93Å; I50-L158 HydrophobicContact CG2-CD1 3.96Å; I50-W242 HydrophobicContact CD1-CD2 4.45Å; I50-W242 HydrophobicContact CD1-CE3 4.04Å; I50-W242 HydrophobicContact CG1-CB 4.39Å; I50-W242 HydrophobicContact CG1-CD2 3.87Å; I50-W242 HydrophobicContact CG1-CE3 3.96Å; I50-W242 HydrophobicContact CG1-CG 4.04Å
51E92.3Very high93.5Very high5 Ų516.9 Ų16.92%0.0238%0.083CC..Hα-helixtrans-56.8-50.1174.5-77173.7171.400112.5I47 T49 G55 L56 S58 S61 K339 S573I47-E51 HydrophobicContact CG2-CG 4.24Å; I47-E51 WeakPolarHBondContact CG2-OE1 3.36Å; I47-E51 WeakPolarHBondContact O-CB 3.46Å; I47-E51 VanDerWaalsContact O-CG 3.3Å; I47-E51 WeakPolarHBondContact O-CG 3.27Å; I47-E51 PolarHBondContact O-N 3.41Å; T49-E51 VanDerWaalsContact C-N 3.31Å; T49-E51 PolarHBondContact O-N 3.44Å; E51-G55 CarbonylContact O-C 3.41Å; E51-G55 WeakPolarHBondContact O-CA 3.46Å; E51-G55 PolarHBondContact O-N 2.93Å; E51-L56 HydrophobicContact CG-CB 4.21Å; E51-L56 PolarHBondContact O-N 2.71Å; E51-L56 VanDerWaalsContact O-N 3.09Å; E51-S58 WeakPolarHBondContact OE1-CA 3.25Å; E51-S61 VanDerWaalsContact CD-OG 3.29Å; E51-S61 WeakPolarHBondContact CG-OG 3.45Å; E51-S61 WeakPolarHBondContact OE1-CB 3.3Å; E51-S61 PolarHBondContact OE1-OG 3.4Å; E51-K339 IonicContact OE1-NZ 2.82Å; E51-K339 WeakPolarHBondContact OE2-CE 3.43Å; E51-K339 IonicContact OE2-NZ 3.79Å; E51-K339 PolarHBondContact OE2-NZ 3.07Å; E51-S573 WeakPolarHBondContact O-CB 3.49Å
52R90.1Very high93.6Very high34 Ų3416.9 Ų16.913%0.1288%0.083CC..Hα-helixtrans-63.7-43.1179.4-72170-176.1-151.9-5.9111.7S48 T49 L236 W238 V239 E342S48-R52 WeakPolarHBondContact O-CD 3.37Å; S48-R52 VanDerWaalsContact O-CG 3.22Å; S48-R52 WeakPolarHBondContact O-CG 3.49Å; S48-R52 PolarHBondContact O-N 2.94Å; T49-R52 PolarHBondContact O-N 3.13Å; R52-L236 PolarHBondContact NH1-O 3.41Å; R52-L236 VanDerWaalsContact NH1-O 3.17Å; R52-W238 PolarHBondContact NH1-O 3.29Å; R52-V239 HydrophobicContact CB-CG2 4.02Å; R52-E342 IonicContact CZ-OE1 3.45Å; R52-E342 IonicContact NE-OE1 3.01Å; R52-E342 IonicContact NH2-OE1 2.78Å; R52-E342 PolarHBondContact NH2-OE1 3.16Å
53R89.3Confident93.6Very high6 Ų619.8 Ų19.82%0.02310%0.098CC..Hα-helixtrans-66-44.2-178-174.5171.6178.6119.13112.6T49 I50 H110 G114 Y116 V219 D220 V239 W242T49-R53 PolarHBondContact O-N 2.9Å; I50-R53 PolarHBondContact O-N 2.88Å; R53-H110 PolarHBondContact NH1-ND1 3.14Å; R53-H110 PolarHBondContact NH2-ND1 3.11Å; R53-G114 PolarHBondContact NH2-O 3.32Å; R53-Y116 HydrophobicContact CG-CD2 4.4Å; R53-V219 VanDerWaalsContact NH1-CG1 3.28Å; R53-D220 IonicContact CZ-OD1 3.46Å; R53-D220 IonicContact NH1-OD1 3.76Å; R53-D220 PolarHBondContact NH1-OD1 3.18Å; R53-D220 IonicContact NH1-OD2 2.64Å; R53-D220 IonicContact NH2-OD1 2.61Å; R53-D220 PolarHBondContact NH2-OD1 3.34Å; R53-D220 VanDerWaalsContact NH2-OD1 3.13Å; R53-V239 HydrophobicContact CB-CG1 3.95Å; R53-W242 VanDerWaalsContact CD-NE1 3.33Å
54Y88.8Confident93.6Very high14 Ų1419.7 Ų19.76%0.05510%0.098CC..Hα-helixtrans-109.57-170.8-63.5-65.4000114.1I50 L56 P109 S113 V154 W242I50-Y54 HydrophobicContact CG2-CD2 4.05Å; I50-Y54 PolarHBondContact O-N 3.01Å; Y54-L56 VanDerWaalsContact C-N 3.32Å; Y54-L56 PolarHBondContact O-N 3.06Å; Y54-P109 VanDerWaalsContact OH-C 3.29Å; Y54-P109 WeakPolarHBondContact OH-CB 3.15Å; Y54-P109 PolarHBondContact OH-O 2.79Å; Y54-S113 WeakPolarHBondContact CE1-OG 3.48Å; Y54-S113 PolarHBondContact OH-OG 3.09Å; Y54-S113 VanDerWaalsContact OH-OG 3.05Å; Y54-V154 HydrophobicContact CD1-CB 4.17Å; Y54-V154 HydrophobicContact CD1-CG1 3.85Å; Y54-V154 HydrophobicContact CD1-CG2 4.07Å; Y54-V154 HydrophobicContact CD2-CG1 3.88Å; Y54-V154 HydrophobicContact CE1-CB 4.18Å; Y54-V154 HydrophobicContact CE1-CG1 3.82Å; Y54-V154 HydrophobicContact CE1-CG2 3.68Å; Y54-V154 HydrophobicContact CE2-CG1 3.82Å; Y54-V154 HydrophobicContact CG-CG1 3.89Å; Y54-W242 HydrophobicContact CE2-CH2 4.28Å; Y54-W242 AromaticContact CE2-CZ2 3.61Å; Y54-W242 HydrophobicContact CE2-CZ2 3.61Å
55G87.8Confident93.5Very high16 Ų1617.9 Ų17.917%0.1659%0.091CC..THydrogen-bonded Turntrans64.432.5177.700000114.2E51 T572 S573E51-G55 CarbonylContact O-C 3.41Å; E51-G55 WeakPolarHBondContact O-CA 3.46Å; E51-G55 PolarHBondContact O-N 2.93Å; G55-T572 CarbonylContact O-C 3.57Å; G55-T572 VanDerWaalsContact O-C 3.27Å; G55-T572 WeakPolarHBondContact O-CA 3.4Å; G55-S573 VanDerWaalsContact C-N 3.34Å; G55-S573 PolarHBondContact O-N 3.39Å
56L91.2Very high93.5Very high11 Ų1118.1 Ų18.16%0.0589%0.093CC..  trans-77.6143-179.8-53.3-179.7000111I50 E51 Y54 K60 Y155 S573I50-L56 HydrophobicContact CG2-CD1 3.93Å; E51-L56 HydrophobicContact CG-CB 4.21Å; E51-L56 PolarHBondContact O-N 2.71Å; E51-L56 VanDerWaalsContact O-N 3.09Å; Y54-L56 VanDerWaalsContact C-N 3.32Å; Y54-L56 PolarHBondContact O-N 3.06Å; L56-K60 HydrophobicContact CB-CB 4.5Å; L56-Y155 HydrophobicContact CD1-CD2 3.9Å; L56-Y155 HydrophobicContact CD1-CE2 4.32Å; L56-Y155 HydrophobicContact CD2-CD2 3.84Å; L56-Y155 HydrophobicContact CD2-CG 4.34Å; L56-S573 WeakPolarHBondContact O-CB 3.28Å
57S93.6Very high93.4Very high21 Ų2120.8 Ų20.815%0.14710%0.104CC..  trans-75.3157.5167.493.70000110.1Q59 K60 S61 D558S57-Q59 PolarHBondContact O-N 3.45Å; S57-Q59 PolarHBondContact OG-N 3.06Å; S57-K60 PolarHBondContact O-N 3.29Å; S57-K60 VanDerWaalsContact O-N 3.11Å; S57-K60 PolarHBondContact OG-N 3.28Å; S57-S61 PolarHBondContact O-N 2.94Å; S57-S61 PolarHBondContact O-OG 3.49Å; S57-D558 WeakPolarHBondContact CB-OD2 3.29Å; S57-D558 PolarHBondContact OG-OD2 2.98Å
58S95.9Very high93.2Very high1 Ų121 Ų211%0.00711%0.106CC..Hα-helixtrans-66.1-31.4-178.8-30.40000111.5E51 S61 G62 F336 K339 G554 I557 D558E51-S58 WeakPolarHBondContact OE1-CA 3.25Å; S58-S61 PolarHBondContact O-N 3.29Å; S58-G62 PolarHBondContact O-N 3.5Å; S58-F336 WeakPolarHBondContact O-CZ 3.47Å; S58-K339 PolarHBondContact OG-NZ 3.07Å; S58-G554 WeakPolarHBondContact CB-O 3.38Å; S58-G554 WeakPolarHBondContact O-CA 3.49Å; S58-I557 WeakPolarHBondContact OG-CG2 3.49Å; S58-D558 WeakPolarHBondContact CA-OD1 3.47Å; S58-D558 WeakPolarHBondContact CB-OD1 3.35Å; S58-D558 PolarHBondContact N-OD1 3.12Å; S58-D558 PolarHBondContact N-OD2 3.24Å; S58-D558 VanDerWaalsContact N-OD2 3.09Å; S58-D558 PolarHBondContact OG-OD1 3.13Å
59Q95.6Very high93.1Very high85 Ų8522.2 Ų22.240%0.39711%0.11SC..Hα-helixtrans-61.1-46.9171-171.7-175.611.600111.9S57 S61 G62 I63 V551 D558S57-Q59 PolarHBondContact O-N 3.45Å; S57-Q59 PolarHBondContact OG-N 3.06Å; Q59-S61 VanDerWaalsContact C-N 3.32Å; Q59-S61 PolarHBondContact O-N 2.9Å; Q59-G62 PolarHBondContact O-N 3.4Å; Q59-G62 VanDerWaalsContact O-N 3.16Å; Q59-I63 WeakPolarHBondContact O-CG1 3.44Å; Q59-I63 PolarHBondContact O-N 3.04Å; Q59-V551 HydrophobicContact CG-CG1 4.12Å; Q59-D558 WeakPolarHBondContact CB-OD2 3.49Å; Q59-D558 PolarHBondContact N-OD2 3.24Å
60K94.9Very high93Very high94 Ų9424.5 Ų24.541%0.40912%0.124SC..Hα-helixtrans-61.4-40.4177.3-73.9-175180177.50111.8L56 S57 G62 I63 L64 Y155L56-K60 HydrophobicContact CB-CB 4.5Å; S57-K60 PolarHBondContact O-N 3.29Å; S57-K60 VanDerWaalsContact O-N 3.11Å; S57-K60 PolarHBondContact OG-N 3.28Å; K60-G62 VanDerWaalsContact C-N 3.34Å; K60-I63 PolarHBondContact O-N 2.99Å; K60-L64 WeakPolarHBondContact O-CB 3.44Å; K60-L64 PolarHBondContact O-N 2.92Å; K60-Y155 HydrophobicContact CB-CE2 3.97Å; K60-Y155 PolarHBondContact O-OH 3.3Å
61S95.3Very high92.6Very high2 Ų224.5 Ų24.51%0.01413%0.125CC..Hα-helixtrans-66.8-35.6174.7-540000112.9E51 S57 S58 Q59 L64 A65E51-S61 VanDerWaalsContact CD-OG 3.29Å; E51-S61 WeakPolarHBondContact CG-OG 3.45Å; E51-S61 WeakPolarHBondContact OE1-CB 3.3Å; E51-S61 PolarHBondContact OE1-OG 3.4Å; S57-S61 PolarHBondContact O-N 2.94Å; S57-S61 PolarHBondContact O-OG 3.49Å; S58-S61 PolarHBondContact O-N 3.29Å; Q59-S61 VanDerWaalsContact C-N 3.32Å; Q59-S61 PolarHBondContact O-N 2.9Å; S61-L64 WeakPolarHBondContact O-CB 3.23Å; S61-L64 PolarHBondContact O-N 3.27Å; S61-A65 WeakPolarHBondContact O-CB 3.49Å; S61-A65 PolarHBondContact O-N 3.5Å
62G96.2Very high92.3Very high0 Ų025.1 Ų25.10%013%0.129CC..Hα-helixtrans-62.4-43.9174.200000111.4S58 Q59 K60 L64 A65 A66 P550S58-G62 PolarHBondContact O-N 3.5Å; Q59-G62 PolarHBondContact O-N 3.4Å; Q59-G62 VanDerWaalsContact O-N 3.16Å; K60-G62 VanDerWaalsContact C-N 3.34Å; G62-L64 VanDerWaalsContact C-N 3.33Å; G62-L64 PolarHBondContact O-N 3.48Å; G62-A65 PolarHBondContact O-N 3Å; G62-A66 WeakPolarHBondContact O-CB 3.39Å; G62-A66 PolarHBondContact O-N 2.89Å; G62-P550 WeakPolarHBondContact O-CB 3.18Å
63I96.2Very high92Very high61 Ų6125.1 Ų25.131%0.31313%0.133SC..Hα-helixtrans-59.7-47.7173-65.6168.9000109.8Q59 K60 A65 A66 F67 L159 V551Q59-I63 WeakPolarHBondContact O-CG1 3.44Å; Q59-I63 PolarHBondContact O-N 3.04Å; K60-I63 PolarHBondContact O-N 2.99Å; I63-A65 PolarHBondContact O-N 2.86Å; I63-A66 PolarHBondContact O-N 3.28Å; I63-A66 VanDerWaalsContact O-N 3.16Å; I63-F67 HydrophobicContact CG2-CD2 4.48Å; I63-F67 WeakPolarHBondContact O-CB 3.2Å; I63-F67 PolarHBondContact O-N 2.86Å; I63-L159 HydrophobicContact CG2-CD2 4.29Å; I63-V551 HydrophobicContact CB-CG2 4.4Å; I63-V551 HydrophobicContact CG1-CG1 4.07Å; I63-V551 HydrophobicContact CG1-CG2 3.69Å
64L95.8Very high91.6Very high2 Ų229.2 Ų29.21%0.0116%0.158CC..Hα-helixtrans-58.7-46-179.9175.761.6000111.9M43 K60 S61 G62 A66 F67 Y155 L158 L159 Q162M43-L64 HydrophobicContact CE-CD1 4.12Å; M43-L64 HydrophobicContact CE-CD2 3.37Å; M43-L64 HydrophobicContact CE-CG 3.4Å; K60-L64 WeakPolarHBondContact O-CB 3.44Å; K60-L64 PolarHBondContact O-N 2.92Å; S61-L64 WeakPolarHBondContact O-CB 3.23Å; S61-L64 PolarHBondContact O-N 3.27Å; G62-L64 VanDerWaalsContact C-N 3.33Å; G62-L64 PolarHBondContact O-N 3.48Å; L64-A66 PolarHBondContact O-N 2.95Å; L64-F67 PolarHBondContact O-N 3.21Å; L64-Y155 HydrophobicContact CB-CE2 4.16Å; L64-L158 HydrophobicContact CD1-CB 3.63Å; L64-L158 HydrophobicContact CD2-CB 4.06Å; L64-L158 HydrophobicContact CD2-CD1 4.03Å; L64-L159 HydrophobicContact CB-CD2 4.34Å; L64-L159 HydrophobicContact CD1-CD2 3.91Å; L64-L159 HydrophobicContact CD1-CG 4.26Å; L64-Q162 HydrophobicContact CD1-CG 3.76Å; L64-Q162 WeakPolarHBondContact O-CG 3.44Å
65A94.1Very high91.4Very high6 Ų631.2 Ų31.25%0.0517%0.169CC..Hα-helixtrans-65.6-24.3179.100000114.1I47 S61 G62 I63 N68 T335I47-A65 HydrophobicContact CD1-CB 3.79Å; S61-A65 WeakPolarHBondContact O-CB 3.49Å; S61-A65 PolarHBondContact O-N 3.5Å; G62-A65 PolarHBondContact O-N 3Å; I63-A65 PolarHBondContact O-N 2.86Å; A65-N68 PolarHBondContact O-OD1 3.4Å; A65-T335 HydrophobicContact CB-CG2 3.69Å
66A94.4Very high91Very high6 Ų632.4 Ų32.45%0.0517%0.171CC..Hα-helixtrans-97.2-10.3-178.300000113.7G62 I63 L64 N68 E69 P550G62-A66 WeakPolarHBondContact O-CB 3.39Å; G62-A66 PolarHBondContact O-N 2.89Å; I63-A66 PolarHBondContact O-N 3.28Å; I63-A66 VanDerWaalsContact O-N 3.16Å; L64-A66 PolarHBondContact O-N 2.95Å; A66-N68 VanDerWaalsContact C-N 3.26Å; A66-N68 PolarHBondContact O-N 2.91Å; A66-E69 WeakPolarHBondContact O-CB 3.48Å; A66-E69 PolarHBondContact O-N 2.96Å; A66-P550 HydrophobicContact CB-CB 4.44Å; A66-P550 HydrophobicContact CB-CG 4.24Å
67F93.9Very high90.2Very high56 Ų5633.6 Ų33.625%0.24618%0.179CC..Hα-helixtrans-69.8-22.7-168-155-112.6000113.7I63 L64 E69 V70 L159 Q162 L163I63-F67 HydrophobicContact CG2-CD2 4.48Å; I63-F67 WeakPolarHBondContact O-CB 3.2Å; I63-F67 PolarHBondContact O-N 2.86Å; L64-F67 PolarHBondContact O-N 3.21Å; F67-E69 PolarHBondContact O-N 3.22Å; F67-V70 HydrophobicContact CD2-CG2 4.09Å; F67-V70 HydrophobicContact CE2-CG2 4.37Å; F67-V70 WeakPolarHBondContact O-CB 3.1Å; F67-V70 PolarHBondContact O-N 3.34Å; F67-L159 HydrophobicContact CB-CD2 3.88Å; F67-L159 HydrophobicContact CD1-CB 4.03Å; F67-L159 HydrophobicContact CD1-CD2 3.9Å; F67-L159 WeakPolarHBondContact CD1-O 3.34Å; F67-L159 HydrophobicContact CD2-CD2 3.93Å; F67-L159 HydrophobicContact CE1-CB 4Å; F67-L159 HydrophobicContact CE1-CD2 4.37Å; F67-L159 HydrophobicContact CE2-CD2 4.43Å; F67-L159 HydrophobicContact CG-CD2 3.64Å; F67-Q162 HydrophobicContact CB-CB 3.96Å; F67-Q162 HydrophobicContact CD1-CB 4.46Å; F67-L163 HydrophobicContact CD1-CB 3.91Å; F67-L163 HydrophobicContact CE1-CB 3.79Å; F67-L163 HydrophobicContact CE1-CD1 4.31Å; F67-L163 HydrophobicContact CE1-CD2 4.41Å; F67-L163 HydrophobicContact CE1-CG 4.39Å
68N91.9Very high89.4Confident12 Ų1236.2 Ų36.26%0.06419%0.188CC..Hα-helixtrans-61.1-30.5171.170.3-43.3000112.7A65 A66 V70 G71 N72 Q162 G166A65-N68 PolarHBondContact O-OD1 3.4Å; A66-N68 VanDerWaalsContact C-N 3.26Å; A66-N68 PolarHBondContact O-N 2.91Å; N68-V70 VanDerWaalsContact C-N 3.26Å; N68-V70 PolarHBondContact O-N 3.11Å; N68-G71 PolarHBondContact O-N 3.4Å; N68-N72 PolarHBondContact O-N 3.15Å; N68-N72 VanDerWaalsContact O-N 3.14Å; N68-Q162 WeakPolarHBondContact CA-O 3.27Å; N68-Q162 WeakPolarHBondContact CB-O 3.38Å; N68-G166 WeakPolarHBondContact O-CA 3.41Å
69E91.1Very high88.5Confident31 Ų3137.1 Ų37.115%0.14519%0.193CC..Hα-helixtrans-69.4-27.1178.3-59.8-56.3144.600112.1A66 F67 N72 T73 R542 F546A66-E69 WeakPolarHBondContact O-CB 3.48Å; A66-E69 PolarHBondContact O-N 2.96Å; F67-E69 PolarHBondContact O-N 3.22Å; E69-N72 PolarHBondContact O-N 3.36Å; E69-T73 VanDerWaalsContact O-CB 3.25Å; E69-T73 WeakPolarHBondContact O-CB 3.1Å; E69-T73 PolarHBondContact O-N 3.33Å; E69-T73 PolarHBondContact O-OG1 2.96Å; E69-R542 IonicContact OE2-NE 3.53Å; E69-F546 HydrophobicContact CG-CB 3.8Å
70V90.3Very high87.2Confident48 Ų4836.9 Ų36.929%0.29120%0.201SC..Hα-helixtrans-62.9-53.3175.4-179.60000109.8F67 N68 N72 T73 V74 L547F67-V70 HydrophobicContact CD2-CG2 4.09Å; F67-V70 HydrophobicContact CE2-CG2 4.37Å; F67-V70 WeakPolarHBondContact O-CB 3.1Å; F67-V70 PolarHBondContact O-N 3.34Å; N68-V70 VanDerWaalsContact C-N 3.26Å; N68-V70 PolarHBondContact O-N 3.11Å; V70-N72 VanDerWaalsContact C-N 3.28Å; V70-N72 PolarHBondContact O-N 3.46Å; V70-T73 PolarHBondContact O-N 3.41Å; V70-V74 WeakPolarHBondContact O-CG2 3.32Å; V70-V74 PolarHBondContact O-N 2.89Å; V70-L547 HydrophobicContact CG2-CD1 3.85Å
71G86Confident86.1Confident3 Ų333.2 Ų33.23%0.03119%0.185CC..Hα-helixtrans-59.8-40177.600000112.3N68 L75N68-G71 PolarHBondContact O-N 3.4Å; G71-L75 PolarHBondContact O-N 3.38Å
72N85.4Confident85Confident19 Ų1937.1 Ų37.110%0.10220%0.202CC..Hα-helixtrans-69.8-41-179.5-157.2-24.5000112.9N68 E69 V70 L75 I76 V170 R542N68-N72 PolarHBondContact O-N 3.15Å; N68-N72 VanDerWaalsContact O-N 3.14Å; E69-N72 PolarHBondContact O-N 3.36Å; V70-N72 VanDerWaalsContact C-N 3.28Å; V70-N72 PolarHBondContact O-N 3.46Å; N72-L75 PolarHBondContact O-N 3.49Å; N72-I76 WeakPolarHBondContact O-CB 3.33Å; N72-I76 PolarHBondContact O-N 3.44Å; N72-V170 HydrophobicContact CB-CG2 4.17Å; N72-V170 WeakPolarHBondContact OD1-CG2 3.4Å; N72-R542 PolarHBondContact ND2-NH2 3.08Å; N72-R542 VanDerWaalsContact ND2-NH2 3.16Å; N72-R542 PolarHBondContact O-NH1 3.44Å; N72-R542 PolarHBondContact OD1-NH1 2.97Å; N72-R542 PolarHBondContact OD1-NH2 2.85Å
73T84.3Confident83.7Confident34 Ų3437.5 Ų37.521%0.20921%0.206CC..Hα-helixtrans-64.8-40.8-178.5-59.30000112.1E69 V70 L75 R542 V543E69-T73 VanDerWaalsContact O-CB 3.25Å; E69-T73 WeakPolarHBondContact O-CB 3.1Å; E69-T73 PolarHBondContact O-N 3.33Å; E69-T73 PolarHBondContact O-OG1 2.96Å; V70-T73 PolarHBondContact O-N 3.41Å; T73-L75 PolarHBondContact O-N 3.46Å; T73-R542 WeakPolarHBondContact OG1-CB 3.48Å; T73-R542 WeakPolarHBondContact OG1-CD 3.47Å; T73-V543 HydrophobicContact CG2-CG2 4.11Å
74V81.1Confident82.3Confident91 Ų9137.3 Ų37.355%0.55221%0.21SC*.Hα-helixtrans-65.7-40-179.8174.50000111.3V70 F78V70-V74 WeakPolarHBondContact O-CG2 3.32Å; V70-V74 PolarHBondContact O-N 2.89Å; V74-F78 VanDerWaalsContact O-CD2 3.26Å; V74-F78 WeakPolarHBondContact O-CD2 3.45Å; V74-F78 VanDerWaalsContact O-CE2 3.29Å; V74-F78 WeakPolarHBondContact O-CE2 3.41Å
75L83.8Confident81.5Confident56 Ų5642.5 Ų42.529%0.29323%0.23SC..Hα-helixtrans-95.3-18.6-169.3-66.8178.8000115.2G71 N72 T73 V77 F78 V79 I167 V170G71-L75 PolarHBondContact O-N 3.38Å; N72-L75 PolarHBondContact O-N 3.49Å; T73-L75 PolarHBondContact O-N 3.46Å; L75-V77 VanDerWaalsContact C-N 3.29Å; L75-V77 PolarHBondContact O-N 2.84Å; L75-F78 HydrophobicContact CD2-CD2 4.36Å; L75-F78 PolarHBondContact O-N 3.25Å; L75-F78 VanDerWaalsContact O-N 3.13Å; L75-V79 PolarHBondContact O-N 3.02Å; L75-I167 HydrophobicContact CD1-CB 3.96Å; L75-I167 HydrophobicContact CD1-CD1 4.5Å; L75-I167 HydrophobicContact CD1-CG1 3.72Å; L75-I167 HydrophobicContact CD1-CG2 3.56Å; L75-V170 HydrophobicContact CB-CB 4.45Å; L75-V170 HydrophobicContact CB-CG1 4.2Å; L75-V170 HydrophobicContact CB-CG2 3.99Å
76I79.1Confident81.1Confident42 Ų4243.3 Ų43.322%0.21523%0.234CC..Hα-helixtrans-64.2-32.9-174.9-164.8149.9000113.6N72 F78 V79 S80 V170N72-I76 WeakPolarHBondContact O-CB 3.33Å; N72-I76 PolarHBondContact O-N 3.44Å; I76-F78 VanDerWaalsContact C-N 3.31Å; I76-F78 PolarHBondContact O-N 3.31Å; I76-V79 PolarHBondContact O-N 2.98Å; I76-S80 PolarHBondContact O-N 3.41Å; I76-S80 VanDerWaalsContact O-N 3.1Å; I76-S80 PolarHBondContact O-OG 3.41Å; I76-V170 HydrophobicContact CB-CG1 3.97Å; I76-V170 HydrophobicContact CG1-CG1 4.31Å
77V74.3Confident80.9Confident36 Ų3644.7 Ų44.722%0.21824%0.239CC..Hα-helixtrans-62.4-41.3176-179.60000110.7L75 F81 F299 L300L75-V77 VanDerWaalsContact C-N 3.29Å; L75-V77 PolarHBondContact O-N 2.84Å; V77-F81 PolarHBondContact O-N 3.45Å; V77-F299 HydrophobicContact CG1-CE1 3.91Å; V77-L300 HydrophobicContact CG1-CD2 4.31Å
78F76.9Confident80.8Confident75 Ų7543.5 Ų43.533%0.32923%0.233SC..Hα-helixtrans-71.2-43.7179.2-62.1-81.6000112.1V74 L75 I76 S80 F81 F82 L296V74-F78 VanDerWaalsContact O-CD2 3.26Å; V74-F78 WeakPolarHBondContact O-CD2 3.45Å; V74-F78 VanDerWaalsContact O-CE2 3.29Å; V74-F78 WeakPolarHBondContact O-CE2 3.41Å; L75-F78 HydrophobicContact CD2-CD2 4.36Å; L75-F78 PolarHBondContact O-N 3.25Å; L75-F78 VanDerWaalsContact O-N 3.13Å; I76-F78 VanDerWaalsContact C-N 3.31Å; I76-F78 PolarHBondContact O-N 3.31Å; F78-S80 PolarHBondContact O-N 3.49Å; F78-F81 WeakPolarHBondContact O-CB 3.33Å; F78-F81 PolarHBondContact O-N 2.86Å; F78-F82 HydrophobicContact CB-CD2 4.33Å; F78-F82 HydrophobicContact CB-CE2 4.2Å; F78-F82 WeakPolarHBondContact O-CD2 3.39Å; F78-F82 PolarHBondContact O-N 3.08Å; F78-L296 HydrophobicContact CD1-CD1 4.41Å; F78-L296 HydrophobicContact CE1-CD2 4.36Å
79V76.8Confident80.9Confident20 Ų2042.9 Ų42.912%0.12123%0.23CC..Hα-helixtrans-58-38.2176.9168.40000111L75 I76 F81 F82 G83 V170 P174 F175L75-V79 PolarHBondContact O-N 3.02Å; I76-V79 PolarHBondContact O-N 2.98Å; V79-F81 VanDerWaalsContact C-N 3.3Å; V79-F81 PolarHBondContact O-N 3.03Å; V79-F82 PolarHBondContact O-N 3.07Å; V79-G83 PolarHBondContact O-N 3.14Å; V79-G83 VanDerWaalsContact O-N 3.15Å; V79-V170 HydrophobicContact CB-CG1 3.97Å; V79-V170 HydrophobicContact CG1-CG1 4.41Å; V79-V170 HydrophobicContact CG2-CB 4.27Å; V79-V170 HydrophobicContact CG2-CG1 3.52Å; V79-P174 HydrophobicContact CG1-CB 4.41Å; V79-P174 HydrophobicContact CG1-CG 4.49Å; V79-F175 HydrophobicContact CB-CZ 4.37Å; V79-F175 HydrophobicContact CG1-CD1 4.05Å; V79-F175 HydrophobicContact CG1-CE1 3.44Å; V79-F175 VanDerWaalsContact CG1-CE1 3.44Å; V79-F175 HydrophobicContact CG1-CE2 4.11Å; V79-F175 HydrophobicContact CG1-CZ 3.51Å; V79-F175 VanDerWaalsContact O-CE1 3.28Å; V79-F175 WeakPolarHBondContact O-CE1 3.44Å
80S68.8Low81Confident81 Ų8149 Ų4957%0.56625%0.252SS*.Hα-helixtrans-64.6-33177.9-55.30000112.6I76 F78I76-S80 PolarHBondContact O-N 3.41Å; I76-S80 VanDerWaalsContact O-N 3.1Å; I76-S80 PolarHBondContact O-OG 3.41Å; F78-S80 PolarHBondContact O-N 3.49Å
81F71.4Confident81.2Confident17 Ų1752.9 Ų52.98%0.07526%0.262CS..Hα-helixtrans-74.7-42.4174.7177.3-99.3000112.7V77 F78 V79 G83 L294 L296 F299V77-F81 PolarHBondContact O-N 3.45Å; F78-F81 WeakPolarHBondContact O-CB 3.33Å; F78-F81 PolarHBondContact O-N 2.86Å; V79-F81 VanDerWaalsContact C-N 3.3Å; V79-F81 PolarHBondContact O-N 3.03Å; F81-G83 VanDerWaalsContact C-N 3.33Å; F81-G83 PolarHBondContact O-N 3.35Å; F81-L294 WeakPolarHBondContact CE2-O 3.04Å; F81-L296 HydrophobicContact CD1-CD1 4.15Å; F81-L296 HydrophobicContact CD1-CG 4.34Å; F81-L296 HydrophobicContact CE1-CB 4.04Å; F81-L296 HydrophobicContact CE1-CD1 4.14Å; F81-L296 HydrophobicContact CE1-CG 4.28Å; F81-L296 HydrophobicContact CZ-CB 4Å; F81-F299 HydrophobicContact CD2-CG 4.49Å
82F72.3Confident81.6Confident83 Ų8352.8 Ų52.836%0.36426%0.26SS..Hα-helixtrans-79-12.7-174.7-69.8-64000114.3F78 V79 S84 R85 V86 L296F78-F82 HydrophobicContact CB-CD2 4.33Å; F78-F82 HydrophobicContact CB-CE2 4.2Å; F78-F82 WeakPolarHBondContact O-CD2 3.39Å; F78-F82 PolarHBondContact O-N 3.08Å; V79-F82 PolarHBondContact O-N 3.07Å; F82-S84 PolarHBondContact O-N 3.44Å; F82-R85 PolarHBondContact O-N 3.34Å; F82-V86 HydrophobicContact CB-CG1 4.05Å; F82-V86 WeakPolarHBondContact O-CG2 3.47Å; F82-V86 PolarHBondContact O-N 3.24Å; F82-L296 HydrophobicContact CE2-CD1 4.38Å; F82-L296 HydrophobicContact CZ-CD1 3.89Å
83G69.6Low82.1Confident8 Ų852 Ų528%0.08226%0.258CS..THydrogen-bonded Turntrans-55.3-43.4-166.300000116.5V79 F81 R85 R88V79-G83 PolarHBondContact O-N 3.14Å; V79-G83 VanDerWaalsContact O-N 3.15Å; F81-G83 VanDerWaalsContact C-N 3.33Å; F81-G83 PolarHBondContact O-N 3.35Å; G83-R85 VanDerWaalsContact C-N 3.32Å; G83-R85 PolarHBondContact O-N 2.86Å; G83-R88 VanDerWaalsContact O-CG 3.28Å; G83-R88 WeakPolarHBondContact O-CG 3.46Å; G83-R88 PolarHBondContact O-NE 3.27Å
84S67.9Low82.7Confident57 Ų5752.4 Ų52.440%0.39927%0.268SS..THydrogen-bonded Turntrans-80.9-11.5178.6600000114F82F82-S84 PolarHBondContact O-N 3.44Å
85R78.5Confident83.4Confident112 Ų11248.4 Ų48.442%0.42325%0.245SC..THydrogen-bonded Turntrans-100.5-13.6-171.9-59-172.6-178.9-173.46.6113.5F82 G83 R292F82-R85 PolarHBondContact O-N 3.34Å; G83-R85 VanDerWaalsContact C-N 3.32Å; G83-R85 PolarHBondContact O-N 2.86Å; R85-R292 PolarHBondContact NH2-O 3.06Å
86V86.1Confident84Confident22 Ų2245.8 Ų45.813%0.13323%0.232CC..SBendtrans-112.4164.5-173.9-59.80000113.2F82 R88 Y91 F175F82-V86 HydrophobicContact CB-CG1 4.05Å; F82-V86 WeakPolarHBondContact O-CG2 3.47Å; F82-V86 PolarHBondContact O-N 3.24Å; V86-R88 VanDerWaalsContact C-N 3.3Å; V86-R88 HydrophobicContact CG2-CG 4.46Å; V86-R88 PolarHBondContact O-N 2.93Å; V86-Y91 HydrophobicContact CB-CD2 3.83Å; V86-Y91 HydrophobicContact CB-CE2 3.59Å; V86-Y91 HydrophobicContact CG1-CE2 3.88Å; V86-Y91 HydrophobicContact CG2-CD2 3.92Å; V86-Y91 HydrophobicContact CG2-CE2 4.15Å; V86-Y91 HydrophobicContact CG2-CG 4.32Å; V86-F175 HydrophobicContact CG2-CE2 4.06Å; V86-F175 HydrophobicContact CG2-CZ 3.99Å
87H90.1Very high84.9Confident36 Ų3647.2 Ų47.217%0.16724%0.239CC..  trans-74.981.6169.9-167.3-45.3000110.4R90 Y91 F263 R265H87-R90 HydrophobicContact CB-CB 4.4Å; H87-R90 PolarHBondContact O-N 3.39Å; H87-Y91 PolarHBondContact O-N 3.39Å; H87-F263 PolarHBondContact CE1-O 3.48Å; H87-R265 HydrophobicContact CB-CG 4.45Å; H87-R265 PolarHBondContact CE1-N 2Å; H87-R265 VanDerWaalsContact CE1-N 3.35Å; H87-R265 WeakPolarHBondContact NE2-CA 3.39Å; H87-R265 PolarHBondContact NE2-N 3.49Å
88R90.9Very high86Confident30 Ų3048 Ų4811%0.11324%0.242CC..Hα-helixtrans-43.8-51.2-172.9-68.9-177.2-155.3160.99.3114.5G83 V86 R90 Y91 I92 F175 S178 Y179 D182G83-R88 VanDerWaalsContact O-CG 3.28Å; G83-R88 WeakPolarHBondContact O-CG 3.46Å; G83-R88 PolarHBondContact O-NE 3.27Å; V86-R88 VanDerWaalsContact C-N 3.3Å; V86-R88 HydrophobicContact CG2-CG 4.46Å; V86-R88 PolarHBondContact O-N 2.93Å; R88-R90 VanDerWaalsContact C-N 3.33Å; R88-R90 PolarHBondContact O-N 3.34Å; R88-Y91 PolarHBondContact O-N 3.5Å; R88-I92 WeakPolarHBondContact O-CG1 3.36Å; R88-I92 PolarHBondContact O-N 3.04Å; R88-F175 HydrophobicContact CB-CB 4.09Å; R88-F175 HydrophobicContact CB-CG 4.33Å; R88-F175 HydrophobicContact CG-CB 4.25Å; R88-F175 HydrophobicContact CG-CD1 4.31Å; R88-F175 HydrophobicContact CG-CG 4.15Å; R88-S178 PolarHBondContact NH1-O 3.4Å; R88-S178 PolarHBondContact NH1-OG 3.11Å; R88-Y179 HydrophobicContact CB-CD2 4.18Å; R88-D182 IonicContact CZ-OD2 3.13Å; R88-D182 IonicContact NH1-OD2 2.65Å; R88-D182 PolarHBondContact NH1-OD2 3.46Å; R88-D182 IonicContact NH2-OD2 2.76Å; R88-D182 PolarHBondContact NH2-OD2 2.94Å
89P93.7Very high86.9Confident0 Ų044.4 Ų44.40%023%0.226CC..Hα-helixtrans-57.1-39.6178.4-29.136.3000114.9F25 Y91 I92 G93 Y179 Y260 F263F25-P89 HydrophobicContact CE2-CG 4.33Å; P89-Y91 PolarHBondContact O-N 3.25Å; P89-I92 WeakPolarHBondContact O-CB 3.25Å; P89-I92 PolarHBondContact O-N 2.88Å; P89-G93 PolarHBondContact O-N 3.3Å; P89-Y179 HydrophobicContact CG-CD2 3.97Å; P89-Y179 HydrophobicContact CG-CE2 3.49Å; P89-Y179 VanDerWaalsContact CG-CE2 3.49Å; P89-Y260 HydrophobicContact CB-CD1 4.09Å; P89-Y260 WeakPolarHBondContact O-CB 3.24Å; P89-Y260 VanDerWaalsContact O-CD1 3.3Å; P89-Y260 WeakPolarHBondContact O-CD1 3.47Å; P89-F263 HydrophobicContact CB-CB 3.76Å; P89-F263 HydrophobicContact CG-CB 4.06Å
90R94.1Very high87.9Confident160 Ų16043.9 Ų43.960%0.60422%0.224SC*.Hα-helixtrans-68.5-35.8179.6-72.6-175.8-177.8-178.40.4112.3H87 R88 G93 G94H87-R90 HydrophobicContact CB-CB 4.4Å; H87-R90 PolarHBondContact O-N 3.39Å; R88-R90 VanDerWaalsContact C-N 3.33Å; R88-R90 PolarHBondContact O-N 3.34Å; R90-G93 PolarHBondContact O-N 3.31Å; R90-G94 PolarHBondContact O-N 2.88Å
91Y93.8Very high89.3Confident129 Ų12945 Ų4551%0.50622%0.222SC..Hα-helixtrans-69.7-35.8174-84.5-99.7000112.2V86 H87 R88 P89 G94 G95 P171 F175V86-Y91 HydrophobicContact CB-CD2 3.83Å; V86-Y91 HydrophobicContact CB-CE2 3.59Å; V86-Y91 HydrophobicContact CG1-CE2 3.88Å; V86-Y91 HydrophobicContact CG2-CD2 3.92Å; V86-Y91 HydrophobicContact CG2-CE2 4.15Å; V86-Y91 HydrophobicContact CG2-CG 4.32Å; H87-Y91 PolarHBondContact O-N 3.39Å; R88-Y91 PolarHBondContact O-N 3.5Å; P89-Y91 PolarHBondContact O-N 3.25Å; Y91-G94 PolarHBondContact O-N 3.29Å; Y91-G95 PolarHBondContact O-N 3.2Å; Y91-P171 WeakPolarHBondContact O-CG 3.48Å; Y91-F175 HydrophobicContact CD1-CE2 4.46Å; Y91-F175 HydrophobicContact CG-CE2 4.19Å
92I95.4Very high90.6Very high0 Ų044.1 Ų44.10%022%0.219CC..Hα-helixtrans-61.2-49.5171.2-63.8166.6000109.8F25 L32 R88 P89 G94 G95 A96 I172 F175 Y260F25-I92 HydrophobicContact CZ-CD1 4.11Å; L32-I92 HydrophobicContact CD2-CG2 3.45Å; L32-I92 VanDerWaalsContact CD2-CG2 3.45Å; R88-I92 WeakPolarHBondContact O-CG1 3.36Å; R88-I92 PolarHBondContact O-N 3.04Å; P89-I92 WeakPolarHBondContact O-CB 3.25Å; P89-I92 PolarHBondContact O-N 2.88Å; I92-G94 PolarHBondContact O-N 3.32Å; I92-G95 PolarHBondContact O-N 3.22Å; I92-A96 WeakPolarHBondContact O-CB 3.4Å; I92-A96 PolarHBondContact O-N 3.36Å; I92-I172 HydrophobicContact CG2-CG1 4.5Å; I92-F175 HydrophobicContact CD1-CB 3.76Å; I92-F175 HydrophobicContact CG1-CB 3.7Å; I92-F175 HydrophobicContact CG1-CD2 4.42Å; I92-Y260 HydrophobicContact CB-CD1 3.79Å; I92-Y260 HydrophobicContact CB-CE1 3.75Å; I92-Y260 HydrophobicContact CD1-CD1 4.47Å; I92-Y260 HydrophobicContact CD1-CE1 3.88Å; I92-Y260 HydrophobicContact CG1-CE1 4.44Å; I92-Y260 HydrophobicContact CG2-CD1 3.7Å; I92-Y260 HydrophobicContact CG2-CD2 4.45Å; I92-Y260 HydrophobicContact CG2-CE1 3.33Å; I92-Y260 HydrophobicContact CG2-CE2 4.15Å; I92-Y260 HydrophobicContact CG2-CG 4.24Å
93G96.1Very high91.7Very high4 Ų440.2 Ų40.24%0.04120%0.201CC..Hα-helixtrans-60-44.7176.900000113.1P89 R90 A96 L97P89-G93 PolarHBondContact O-N 3.3Å; R90-G93 PolarHBondContact O-N 3.31Å; G93-A96 WeakPolarHBondContact O-CB 3.5Å; G93-A96 PolarHBondContact O-N 3.34Å; G93-L97 WeakPolarHBondContact O-CG 3.22Å; G93-L97 PolarHBondContact O-N 3.1Å
94G96.1Very high93Very high41 Ų4143.1 Ų43.142%0.42322%0.215SC..Hα-helixtrans-62.6-42.9176.200000113.1R90 Y91 I92 L97 L98R90-G94 PolarHBondContact O-N 2.88Å; Y91-G94 PolarHBondContact O-N 3.29Å; I92-G94 PolarHBondContact O-N 3.32Å; G94-L97 PolarHBondContact O-N 3.5Å; G94-L98 PolarHBondContact O-N 2.93Å
95G95.5Very high94.4Very high8 Ų842.1 Ų42.18%0.08221%0.205CC..Hα-helixtrans-62.8-41.4173.300000112.7Y91 I92 L98 A99 G168Y91-G95 PolarHBondContact O-N 3.2Å; I92-G95 PolarHBondContact O-N 3.22Å; G95-L98 PolarHBondContact O-N 3.32Å; G95-A99 WeakPolarHBondContact O-CB 3.38Å; G95-A99 PolarHBondContact O-N 3.23Å; G95-G168 CarbonylContact C-O 3.16Å; G95-G168 WeakPolarHBondContact CA-O 3.33Å; G95-G168 CarbonylContact O-C 3.42Å; G95-G168 VanDerWaalsContact O-CA 3.23Å; G95-G168 WeakPolarHBondContact O-CA 3.24Å; G95-G168 VanDerWaalsContact O-O 3.11Å
96A97.1Very high95.2Very high0 Ų036.8 Ų36.80%019%0.185CC..Hα-helixtrans-63.6-41.3175.700000112.8L32 I92 G93 A99 C100 I172 A257L32-A96 HydrophobicContact CD1-CB 3.56Å; L32-A96 HydrophobicContact CD2-CB 4.05Å; L32-A96 HydrophobicContact CG-CB 4.43Å; I92-A96 WeakPolarHBondContact O-CB 3.4Å; I92-A96 PolarHBondContact O-N 3.36Å; G93-A96 WeakPolarHBondContact O-CB 3.5Å; G93-A96 PolarHBondContact O-N 3.34Å; A96-A99 PolarHBondContact O-N 3.29Å; A96-C100 WeakPolarHBondContact O-CB 3.5Å; A96-C100 PolarHBondContact O-N 3.23Å; A96-I172 HydrophobicContact CB-CD1 4.41Å; A96-A257 HydrophobicContact CB-CB 3.68Å
97L97.8Very high95.7Very high73 Ų7335.8 Ų35.838%0.38218%0.179SC..Hα-helixtrans-65.3-39.1174.3-71174.1000111.8G93 G94 C100 L101 F254 A257G93-L97 WeakPolarHBondContact O-CG 3.22Å; G93-L97 PolarHBondContact O-N 3.1Å; G94-L97 PolarHBondContact O-N 3.5Å; L97-C100 WeakPolarHBondContact O-CB 3.41Å; L97-C100 PolarHBondContact O-N 2.95Å; L97-L101 PolarHBondContact O-N 3.35Å; L97-F254 HydrophobicContact CD2-CD2 3.87Å; L97-F254 HydrophobicContact CD2-CE2 4.06Å; L97-A257 HydrophobicContact CD2-CB 4.05Å; L97-A257 HydrophobicContact CG-CB 4.24Å
98L97.3Very high95.9Very high51 Ų5136.3 Ų36.327%0.26718%0.184SC..Hα-helixtrans-64.4-41.7173.4-176.461.5000111.6G94 G95 C100 L101 A102 L164 I167G94-L98 PolarHBondContact O-N 2.93Å; G95-L98 PolarHBondContact O-N 3.32Å; L98-C100 VanDerWaalsContact C-N 3.32Å; L98-C100 PolarHBondContact O-N 3.39Å; L98-L101 PolarHBondContact O-N 3.36Å; L98-A102 VanDerWaalsContact O-CB 3.31Å; L98-A102 WeakPolarHBondContact O-CB 3.5Å; L98-A102 PolarHBondContact O-N 3.19Å; L98-L164 HydrophobicContact CD1-CD2 4.35Å; L98-I167 HydrophobicContact CD2-CB 4.16Å; L98-I167 HydrophobicContact CD2-CG2 3.5Å; L98-I167 VanDerWaalsContact CD2-CG2 3.5Å
99A96.8Very high96Very high0 Ų034.9 Ų34.90%018%0.179CC..Hα-helixtrans-63.3-37174.100000112.2G95 A96 A102 S103 L165 L253G95-A99 WeakPolarHBondContact O-CB 3.38Å; G95-A99 PolarHBondContact O-N 3.23Å; A96-A99 PolarHBondContact O-N 3.29Å; A99-A102 PolarHBondContact O-N 3.42Å; A99-S103 WeakPolarHBondContact O-CB 3.45Å; A99-S103 PolarHBondContact O-N 3.48Å; A99-L165 HydrophobicContact CB-CD1 3.86Å; A99-L253 HydrophobicContact CB-CD1 4.45Å
100C97.5Very high95.9Very high10 Ų1034.9 Ų34.97%0.06818%0.179CC..Hα-helixtrans-61.8-50172.3176.80000111.2A96 L97 L98 A102 S103 L104 S250 L253A96-C100 WeakPolarHBondContact O-CB 3.5Å; A96-C100 PolarHBondContact O-N 3.23Å; L97-C100 WeakPolarHBondContact O-CB 3.41Å; L97-C100 PolarHBondContact O-N 2.95Å; L98-C100 VanDerWaalsContact C-N 3.32Å; L98-C100 PolarHBondContact O-N 3.39Å; C100-A102 VanDerWaalsContact C-N 3.3Å; C100-A102 PolarHBondContact O-N 3.43Å; C100-S103 PolarHBondContact O-N 3.36Å; C100-L104 PolarHBondContact O-N 3.19Å; C100-S250 PolarHBondContact SG-O 3.31Å; C100-S250 VanDerWaalsContact SG-O 3.36Å; C100-L253 HydrophobicContact CB-CB 4.21Å
101L97.8Very high95.7Very high103 Ų10332.6 Ų32.654%0.53917%0.173SC..Hα-helixtrans-60.8-40.8177.1-179.261.6000111.6L97 L98 L104 L105L97-L101 PolarHBondContact O-N 3.35Å; L98-L101 PolarHBondContact O-N 3.36Å; L101-L104 PolarHBondContact O-N 2.92Å; L101-L105 WeakPolarHBondContact O-CB 3.49Å; L101-L105 PolarHBondContact O-N 3.03Å
102A97.5Very high95.5Very high0 Ų032 Ų320%018%0.178CC..Hα-helixtrans-61.1-43.8174.800000112.2L98 A99 C100 L105 M106 G161 L164 L165L98-A102 VanDerWaalsContact O-CB 3.31Å; L98-A102 WeakPolarHBondContact O-CB 3.5Å; L98-A102 PolarHBondContact O-N 3.19Å; A99-A102 PolarHBondContact O-N 3.42Å; C100-A102 VanDerWaalsContact C-N 3.3Å; C100-A102 PolarHBondContact O-N 3.43Å; A102-L105 WeakPolarHBondContact O-CB 3.48Å; A102-L105 PolarHBondContact O-N 3.31Å; A102-M106 WeakPolarHBondContact O-CG 3.36Å; A102-M106 PolarHBondContact O-N 3.38Å; A102-G161 WeakPolarHBondContact CB-O 3.45Å; A102-L164 HydrophobicContact CB-CB 3.69Å; A102-L165 HydrophobicContact CB-CB 3.89Å; A102-L165 VanDerWaalsContact CB-N 3.32Å
103S97Very high95Very high0 Ų032.5 Ų32.50%018%0.182CC..Hα-helixtrans-64.5-39.1175.1-174.40000111.9A99 C100 M106 A107 F246A99-S103 WeakPolarHBondContact O-CB 3.45Å; A99-S103 PolarHBondContact O-N 3.48Å; C100-S103 PolarHBondContact O-N 3.36Å; S103-M106 WeakPolarHBondContact O-CB 3.46Å; S103-M106 PolarHBondContact O-N 2.81Å; S103-A107 PolarHBondContact O-N 3.45Å; S103-F246 WeakPolarHBondContact O-CB 3.41Å; S103-F246 PolarHBondContact OG-O 3.41Å; S103-F246 VanDerWaalsContact OG-O 3.08Å
104L97.1Very high94.3Very high69 Ų6934.4 Ų34.436%0.36120%0.202SC..Hα-helixtrans-62.9-43.2172.7-72.5169.9000111.4C100 L101 M106 A107 V108 L247 S250C100-L104 PolarHBondContact O-N 3.19Å; L101-L104 PolarHBondContact O-N 2.92Å; L104-M106 PolarHBondContact O-N 3.48Å; L104-A107 WeakPolarHBondContact O-CB 3.39Å; L104-A107 PolarHBondContact O-N 2.85Å; L104-V108 PolarHBondContact O-N 3.37Å; L104-L247 HydrophobicContact CD2-CD2 3.85Å; L104-S250 VanDerWaalsContact CD2-OG 3.24Å; L104-S250 WeakPolarHBondContact CD2-OG 3.49Å
105L96.7Very high93.7Very high37 Ų3737.2 Ų37.219%0.19420%0.204CC..Hα-helixtrans-58.5-35176.9-167.664.8000112.1L101 A102 A107 V108 P109 L157 L160 L164L101-L105 WeakPolarHBondContact O-CB 3.49Å; L101-L105 PolarHBondContact O-N 3.03Å; A102-L105 WeakPolarHBondContact O-CB 3.48Å; A102-L105 PolarHBondContact O-N 3.31Å; L105-A107 VanDerWaalsContact C-N 3.27Å; L105-A107 PolarHBondContact O-N 2.84Å; L105-V108 HydrophobicContact CD1-CG2 4.39Å; L105-V108 WeakPolarHBondContact O-CB 3.09Å; L105-V108 PolarHBondContact O-N 3.44Å; L105-P109 WeakPolarHBondContact O-CD 3.17Å; L105-L157 HydrophobicContact CD1-CD1 3.55Å; L105-L157 HydrophobicContact CD1-CG 4.49Å; L105-L157 HydrophobicContact CD2-CD1 4.25Å; L105-L157 HydrophobicContact CG-CD1 3.84Å; L105-L160 HydrophobicContact CD2-CB 4.37Å; L105-L160 HydrophobicContact CD2-CD2 4.04Å; L105-L160 HydrophobicContact CD2-CG 3.92Å; L105-L164 HydrophobicContact CD2-CD1 3.97Å
106M95.6Very high93.2Very high0 Ų038 Ų380%021%0.205CC..Hα-helixtrans-64.2-28.8174-69.2-67.5-59.100113M43 A102 S103 L104 P109 L158 Q162 W242 F246M43-M106 HydrophobicContact CE-CE 3.7Å; M43-M106 HydrophobicContact SD-CE 3.42Å; M43-M106 WeakPolarHBondContact SD-CE 3.43Å; A102-M106 WeakPolarHBondContact O-CG 3.36Å; A102-M106 PolarHBondContact O-N 3.38Å; S103-M106 WeakPolarHBondContact O-CB 3.46Å; S103-M106 PolarHBondContact O-N 2.81Å; L104-M106 PolarHBondContact O-N 3.48Å; M106-P109 VanDerWaalsContact O-CD 3.31Å; M106-P109 WeakPolarHBondContact O-CD 3.45Å; M106-L158 HydrophobicContact CE-CB 4.38Å; M106-L158 HydrophobicContact CE-CD2 3.48Å; M106-L158 VanDerWaalsContact CE-CD2 3.48Å; M106-L158 HydrophobicContact SD-CB 4.38Å; M106-L158 HydrophobicContact SD-CD2 3.95Å; M106-Q162 HydrophobicContact CE-CG 4.36Å; M106-Q162 HydrophobicContact SD-CG 4.07Å; M106-W242 WeakPolarHBondContact O-CZ3 3.38Å; M106-F246 HydrophobicContact CB-CD1 3.89Å; M106-F246 HydrophobicContact CB-CD2 4.03Å; M106-F246 HydrophobicContact CB-CE1 4.03Å; M106-F246 HydrophobicContact CB-CE2 4.16Å; M106-F246 HydrophobicContact CB-CG 3.91Å; M106-F246 HydrophobicContact CB-CZ 4.18Å; M106-F246 HydrophobicContact CE-CE1 4.45Å; M106-F246 HydrophobicContact CE-CE2 4.39Å; M106-F246 HydrophobicContact CE-CZ 3.96Å; M106-F246 HydrophobicContact CG-CE1 4.4Å
107A96.2Very high92.1Very high1 Ų140.2 Ų40.21%0.00822%0.216CC..Hα-helixtrans-81-26.2177.400000113.3S103 L104 L105 H110 F111 W243 F246 L247S103-A107 PolarHBondContact O-N 3.45Å; L104-A107 WeakPolarHBondContact O-CB 3.39Å; L104-A107 PolarHBondContact O-N 2.85Å; L105-A107 VanDerWaalsContact C-N 3.27Å; L105-A107 PolarHBondContact O-N 2.84Å; A107-H110 PolarHBondContact O-N 2.88Å; A107-F111 HydrophobicContact CB-CE2 4.43Å; A107-W243 HydrophobicContact CB-CB 4.42Å; A107-F246 HydrophobicContact CB-CB 3.95Å; A107-L247 HydrophobicContact CB-CD2 3.81Å; A107-L247 HydrophobicContact CB-CG 4.22Å
108V94.3Very high91.1Very high47 Ų4737.4 Ų37.429%0.28520%0.2SC..Hα-helixtrans-50.8-41.4-176.2173.60000114.6L104 L105 H110 F111 L112 L157L104-V108 PolarHBondContact O-N 3.37Å; L105-V108 HydrophobicContact CD1-CG2 4.39Å; L105-V108 WeakPolarHBondContact O-CB 3.09Å; L105-V108 PolarHBondContact O-N 3.44Å; V108-H110 PolarHBondContact O-N 3.16Å; V108-H110 VanDerWaalsContact O-N 3.08Å; V108-F111 PolarHBondContact O-N 3.13Å; V108-L112 HydrophobicContact CG1-CD1 3.56Å; V108-L112 HydrophobicContact CG1-CG 3.75Å; V108-L112 PolarHBondContact O-N 2.92Å; V108-L112 VanDerWaalsContact O-N 3.13Å; V108-L157 HydrophobicContact CB-CD2 4.31Å; V108-L157 HydrophobicContact CG1-CD2 4Å
109P92.5Very high89.5Confident0 Ų036.4 Ų36.40%020%0.197CC..Hα-helixtrans-54.1-33.7-177.8-25.831.3000114.4Y54 L105 M106 F111 L112 S113 V154 L157 L158 W242Y54-P109 VanDerWaalsContact OH-C 3.29Å; Y54-P109 WeakPolarHBondContact OH-CB 3.15Å; Y54-P109 PolarHBondContact OH-O 2.79Å; L105-P109 WeakPolarHBondContact O-CD 3.17Å; M106-P109 VanDerWaalsContact O-CD 3.31Å; M106-P109 WeakPolarHBondContact O-CD 3.45Å; P109-F111 VanDerWaalsContact C-N 3.34Å; P109-F111 PolarHBondContact O-N 2.85Å; P109-L112 PolarHBondContact O-N 3.07Å; P109-S113 VanDerWaalsContact O-CB 3.24Å; P109-S113 WeakPolarHBondContact O-CB 3.28Å; P109-S113 PolarHBondContact O-N 2.86Å; P109-S113 PolarHBondContact O-OG 3.33Å; P109-V154 HydrophobicContact CB-CB 4.41Å; P109-V154 HydrophobicContact CB-CG1 3.7Å; P109-V154 HydrophobicContact CB-CG2 4.07Å; P109-V154 HydrophobicContact CG-CG1 4.13Å; P109-L157 HydrophobicContact CG-CD2 3.89Å; P109-L157 HydrophobicContact CG-CG 4.36Å; P109-L158 HydrophobicContact CG-CD2 3.86Å; P109-L158 HydrophobicContact CG-CG 4.13Å; P109-W242 HydrophobicContact CB-CH2 4.01Å; P109-W242 HydrophobicContact CG-CH2 4.26Å
110H91.7Very high87.9Confident0 Ų038.1 Ų38.10%021%0.206CC..Hα-helixtrans-64.5-38.7178.3169.378000112.4R53 A107 V108 V219 D220 D222 K223 W242 W243R53-H110 PolarHBondContact NH1-ND1 3.14Å; R53-H110 PolarHBondContact NH2-ND1 3.11Å; A107-H110 PolarHBondContact O-N 2.88Å; V108-H110 PolarHBondContact O-N 3.16Å; V108-H110 VanDerWaalsContact O-N 3.08Å; H110-V219 PolarHBondContact CE1-O 2.86Å; H110-D220 IonicContact CE1-OD1 3.56Å; H110-D220 PolarHBondContact CE1-OD1 3.48Å; H110-D220 IonicContact ND1-OD1 3.74Å; H110-D222 IonicContact CE1-OD1 2.82Å; H110-D222 IonicContact NE2-OD1 3.13Å; H110-D222 PolarHBondContact NE2-OD1 3.2Å; H110-D222 IonicContact NE2-OD2 3.5Å; H110-D222 PolarHBondContact NE2-OD2 3.47Å; H110-K223 PolarHBondContact O-NZ 2.99Å; H110-W242 HydrophobicContact CB-CH2 4.27Å; H110-W242 HydrophobicContact CB-CZ2 3.85Å; H110-W243 HydrophobicContact CB-CB 3.67Å; H110-W243 HydrophobicContact CB-CG 3.71Å; H110-W243 AromaticContact CD2-CD1 3.53Å; H110-W243 AromaticContact CD2-CD2 3.67Å; H110-W243 AromaticContact CD2-CE2 3.57Å; H110-W243 AromaticContact CD2-CG 3.65Å; H110-W243 AromaticContact CD2-NE1 3.48Å; H110-W243 PolarHBondContact CD2-NE1 2.99Å; H110-W243 AromaticContact CE1-CD1 3.65Å; H110-W243 AromaticContact CE1-CE2 3.9Å; H110-W243 AromaticContact CE1-NE1 3.22Å; H110-W243 PolarHBondContact CE1-NE1 3.26Å; H110-W243 AromaticContact CG-CD1 3.19Å; H110-W243 AromaticContact CG-CG 3.51Å; H110-W243 AromaticContact CG-NE1 3.54Å; H110-W243 AromaticContact ND1-CD1 3.28Å; H110-W243 VanDerWaalsContact ND1-CD1 3.28Å; H110-W243 AromaticContact ND1-NE1 3.4Å; H110-W243 PolarHBondContact ND1-NE1 3.18Å; H110-W243 AromaticContact NE2-CD1 3.82Å; H110-W243 AromaticContact NE2-CE2 3.49Å; H110-W243 AromaticContact NE2-CZ2 3.85Å; H110-W243 AromaticContact NE2-NE1 3.3Å; H110-W243 PolarHBondContact NE2-NE1 3.45Å
111F91.1Very high85.6Confident111 Ų11139.7 Ų39.749%0.48721%0.212SC..Hα-helixtrans-77-28.7179.9-58.9-70.9000112.8A107 V108 P109 W243 L247A107-F111 HydrophobicContact CB-CE2 4.43Å; V108-F111 PolarHBondContact O-N 3.13Å; P109-F111 VanDerWaalsContact C-N 3.34Å; P109-F111 PolarHBondContact O-N 2.85Å; F111-W243 HydrophobicContact CE1-CZ3 4.38Å; F111-W243 HydrophobicContact CE2-CE3 4.28Å; F111-W243 HydrophobicContact CZ-CD2 4.43Å; F111-W243 AromaticContact CZ-CE3 3.71Å; F111-W243 HydrophobicContact CZ-CE3 3.71Å; F111-W243 AromaticContact CZ-CZ3 3.79Å; F111-W243 HydrophobicContact CZ-CZ3 3.79Å; F111-L247 HydrophobicContact CZ-CD1 4.21Å
112L88.3Confident83.3Confident116 Ų11638.4 Ų38.461%0.60721%0.206SC*.Hα-helixtrans-79.3-26.6174-63.5-178.9000112.9V108 P109 L157V108-L112 HydrophobicContact CG1-CD1 3.56Å; V108-L112 HydrophobicContact CG1-CG 3.75Å; V108-L112 PolarHBondContact O-N 2.92Å; V108-L112 VanDerWaalsContact O-N 3.13Å; P109-L112 PolarHBondContact O-N 3.07Å; L112-L157 HydrophobicContact CD1-CD2 4.06Å
113S85.3Confident81.1Confident11 Ų1140.2 Ų40.28%0.07722%0.216CC..SBendtrans-83.4146.1-179.2-560000111.3Y54 P109 K223Y54-S113 WeakPolarHBondContact CE1-OG 3.48Å; Y54-S113 PolarHBondContact OH-OG 3.09Å; Y54-S113 VanDerWaalsContact OH-OG 3.05Å; P109-S113 VanDerWaalsContact O-CB 3.24Å; P109-S113 WeakPolarHBondContact O-CB 3.28Å; P109-S113 PolarHBondContact O-N 2.86Å; P109-S113 PolarHBondContact O-OG 3.33Å; S113-K223 PolarHBondContact O-NZ 3.04Å
114G82.1Confident78.5Confident45 Ų4545.2 Ų45.246%0.46425%0.247SC..  trans-59.2-179.5166.500000113.3R53R53-G114 PolarHBondContact NH2-O 3.32Å
115H82.1Confident75.8Confident99 Ų9946.5 Ų46.546%0.45826%0.262SS..  trans-61.3149.417163.9-83.5000110.1I117H115-I117 VanDerWaalsContact NE2-CG1 3.33Å; H115-I117 WeakPolarHBondContact NE2-CG1 3.45Å; H115-I117 PolarHBondContact O-N 2.87Å
116Y84.9Confident73.1Confident25 Ų2550.6 Ų50.610%0.09829%0.289CS..  trans-74.2110.2179.7172.6-114.6000109.3R53 Y118 Y218 V219 D220 R237 V239R53-Y116 HydrophobicContact CG-CD2 4.4Å; Y116-Y118 HydrophobicContact CD1-CD1 4.34Å; Y116-Y118 HydrophobicContact CE1-CD1 4.29Å; Y116-Y218 WeakPolarHBondContact CD1-OH 3.44Å; Y116-V219 HydrophobicContact CD1-CG1 4.49Å; Y116-V219 HydrophobicContact CG-CG1 4.41Å; Y116-D220 WeakPolarHBondContact CA-OD2 3.38Å; Y116-D220 WeakPolarHBondContact CB-OD2 3.09Å; Y116-D220 PolarHBondContact N-OD2 2.81Å; Y116-R237 WeakPolarHBondContact CE1-O 3.41Å; Y116-R237 PolarHBondContact OH-O 2.96Å; Y116-R237 VanDerWaalsContact OH-O 3.11Å; Y116-V239 HydrophobicContact CD1-CG2 4.15Å; Y116-V239 HydrophobicContact CD2-CG2 4.42Å; Y116-V239 HydrophobicContact CE1-CB 4.38Å; Y116-V239 HydrophobicContact CE1-CG2 3.63Å; Y116-V239 HydrophobicContact CE2-CG2 3.93Å; Y116-V239 VanDerWaalsContact CZ-CG2 3.5Å
117I75.8Confident70.5Confident47 Ų4756.6 Ų56.624%0.24132%0.321CS..  trans-91.5124.2-179.2-61.9171.8000109.3H115 I122H115-I117 VanDerWaalsContact NE2-CG1 3.33Å; H115-I117 WeakPolarHBondContact NE2-CG1 3.45Å; H115-I117 PolarHBondContact O-N 2.87Å; I117-I122 HydrophobicContact CG2-CB 4.45Å; I117-I122 HydrophobicContact CG2-CD1 3.6Å; I117-I122 HydrophobicContact CG2-CG1 3.08Å
118Y75.8Confident68.2Low13 Ų1363.8 Ų63.85%0.05136%0.359CS..  trans-123.8160.9171.764.3-85.1000110.5Y116 D120 M121 I122 L231Y116-Y118 HydrophobicContact CD1-CD1 4.34Å; Y116-Y118 HydrophobicContact CE1-CD1 4.29Å; Y118-D120 VanDerWaalsContact C-N 3.31Å; Y118-D120 HydrophobicContact CD2-CB 3.97Å; Y118-D120 HydrophobicContact CE2-CB 3.61Å; Y118-D120 PolarHBondContact O-N 3.37Å; Y118-D120 VanDerWaalsContact O-N 3.1Å; Y118-M121 HydrophobicContact CD1-CE 4.39Å; Y118-M121 HydrophobicContact CD1-CG 4.29Å; Y118-M121 HydrophobicContact CE1-CB 4.44Å; Y118-M121 HydrophobicContact CE1-CE 3.84Å; Y118-M121 HydrophobicContact CE1-CG 3.68Å; Y118-M121 HydrophobicContact CE1-SD 4.42Å; Y118-M121 HydrophobicContact CE2-CG 4.27Å; Y118-M121 PolarHBondContact O-N 2.88Å; Y118-I122 PolarHBondContact O-N 3.23Å; Y118-L231 HydrophobicContact CD1-CD1 4Å; Y118-L231 HydrophobicContact CD2-CD1 4.35Å; Y118-L231 HydrophobicContact CD2-CD2 4.46Å; Y118-L231 HydrophobicContact CE1-CD1 3.7Å; Y118-L231 HydrophobicContact CE1-CG 4.32Å; Y118-L231 HydrophobicContact CE2-CD1 4.07Å; Y118-L231 HydrophobicContact CE2-CD2 3.98Å; Y118-L231 HydrophobicContact CE2-CG 4.11Å; Y118-L231 HydrophobicContact CG-CD1 4.32Å
119T64.3Low66.1Low31 Ų3168.4 Ų68.419%0.1938%0.375CS..Hα-helixtrans-50-41.4-166.1-42.60000115M121 T123 A436 F437T119-M121 VanDerWaalsContact C-N 3.34Å; T119-M121 PolarHBondContact O-N 3Å; T119-T123 PolarHBondContact O-OG1 3.44Å; T119-A436 HydrophobicContact CG2-CB 3.8Å; T119-F437 VanDerWaalsContact CB-O 3.29Å; T119-F437 WeakPolarHBondContact CB-O 3.42Å; T119-F437 PolarHBondContact OG1-N 3.21Å; T119-F437 PolarHBondContact OG1-O 3.22Å
120D61.8Low64.5Low35 Ų3569.8 Ų69.819%0.18739%0.385CS..Hα-helixtrans-61.6-40.8179-100-30.2000112.3Y118 T123 R237 N438Y118-D120 VanDerWaalsContact C-N 3.31Å; Y118-D120 HydrophobicContact CD2-CB 3.97Å; Y118-D120 HydrophobicContact CE2-CB 3.61Å; Y118-D120 PolarHBondContact O-N 3.37Å; Y118-D120 VanDerWaalsContact O-N 3.1Å; D120-T123 PolarHBondContact O-N 2.91Å; D120-T123 PolarHBondContact O-OG1 2.96Å; D120-R237 IonicContact OD2-CZ 3.28Å; D120-R237 IonicContact OD2-NH1 3.82Å; D120-R237 PolarHBondContact OD2-NH1 3.45Å; D120-R237 IonicContact OD2-NH2 3.11Å; D120-N438 PolarHBondContact OD1-ND2 3.34Å; D120-N438 PolarHBondContact OD2-ND2 3.33Å
121M50.5Low63.3Low43 Ų4371.2 Ų71.221%0.21240%0.4CS..Hα-helixtrans-76.7-27.2-177.2-77.7-129.2-8100114.5Y118 T119 T123 T124 L224Y118-M121 HydrophobicContact CD1-CE 4.39Å; Y118-M121 HydrophobicContact CD1-CG 4.29Å; Y118-M121 HydrophobicContact CE1-CB 4.44Å; Y118-M121 HydrophobicContact CE1-CE 3.84Å; Y118-M121 HydrophobicContact CE1-CG 3.68Å; Y118-M121 HydrophobicContact CE1-SD 4.42Å; Y118-M121 HydrophobicContact CE2-CG 4.27Å; Y118-M121 PolarHBondContact O-N 2.88Å; T119-M121 VanDerWaalsContact C-N 3.34Å; T119-M121 PolarHBondContact O-N 3Å; M121-T123 PolarHBondContact O-N 3.41Å; M121-T124 PolarHBondContact O-OG1 3.13Å; M121-L224 HydrophobicContact CE-CD1 4.01Å
122I49.6Very low62.8Low77 Ų7766.8 Ų66.840%0.39538%0.381SS..Hα-helixtrans-60.7-31.5175.3-63.2174.1000110.3I117 Y118 S125I117-I122 HydrophobicContact CG2-CB 4.45Å; I117-I122 HydrophobicContact CG2-CD1 3.6Å; I117-I122 HydrophobicContact CG2-CG1 3.08Å; Y118-I122 PolarHBondContact O-N 3.23Å; I122-S125 PolarHBondContact O-OG 3.43Å
123T49.7Very low62.5Low37 Ų3761.5 Ų61.523%0.22735%0.354CS..Hα-helixtrans-93.6-14.9-16819.30000114.7T119 D120 M121 S125 S130T119-T123 PolarHBondContact O-OG1 3.44Å; D120-T123 PolarHBondContact O-N 2.91Å; D120-T123 PolarHBondContact O-OG1 2.96Å; M121-T123 PolarHBondContact O-N 3.41Å; T123-S125 PolarHBondContact O-N 2.94Å; T123-S130 VanDerWaalsContact CB-CB 3.47Å; T123-S130 WeakPolarHBondContact CB-OG 3.39Å; T123-S130 WeakPolarHBondContact O-CB 3.31Å; T123-S130 PolarHBondContact O-OG 3.33Å
124T43.7Very low62.2Low105 Ų10566.2 Ų66.264%0.64437%0.373SS*.THydrogen-bonded Turntrans-72.5-4.2-178.944.70000114.7M121M121-T124 PolarHBondContact O-OG1 3.13Å
125S40.9Very low61.3Low96 Ų9668.2 Ų68.267%0.67138%0.38SS*.THydrogen-bonded Turntrans-82.2-7.7-17452.60000115.8I122 T123I122-S125 PolarHBondContact O-OG 3.43Å; T123-S125 PolarHBondContact O-N 2.94Å
126T38.3Very low60.1Low124 Ų12466.7 Ų66.776%0.76138%0.381SS*.THydrogen-bonded Turntrans-150.5-6.517717.30000120.3
127D42.7Very low58.5Low125 Ų12573 Ų7367%0.66842%0.415SS*.  trans-164.6134.6174.2-105.4-36.1000113.3K129 S130D127-K129 PolarHBondContact O-N 3.38Å; D127-S130 VanDerWaalsContact O-CB 3.28Å; D127-S130 WeakPolarHBondContact O-CB 3.47Å; D127-S130 PolarHBondContact O-N 3Å; D127-S130 PolarHBondContact O-OG 3.46Å
128N46.1Very low57.2Low153 Ų15375.2 Ų75.282%0.81843%0.433SS*.THydrogen-bonded Turntrans-60.62.8-179.4-84.6-22.8000116
129K51.2Low55.7Low144 Ų14479.5 Ų79.563%0.62646%0.464SS*.THydrogen-bonded Turntrans-109.23.7-178.2-65.3-179179.9174.70113.9D127D127-K129 PolarHBondContact O-N 3.38Å
130S58Low54.8Low29 Ų2985.1 Ų85.120%0.20349%0.493CS..THydrogen-bonded Turntrans-78.1129.7-168.362.20000112.8T123 D127T123-S130 VanDerWaalsContact CB-CB 3.47Å; T123-S130 WeakPolarHBondContact CB-OG 3.39Å; T123-S130 WeakPolarHBondContact O-CB 3.31Å; T123-S130 PolarHBondContact O-OG 3.33Å; D127-S130 VanDerWaalsContact O-CB 3.28Å; D127-S130 WeakPolarHBondContact O-CB 3.47Å; D127-S130 PolarHBondContact O-N 3Å; D127-S130 PolarHBondContact O-OG 3.46Å
131G67.7Low54.2Low30 Ų3089.3 Ų89.331%0.30951%0.512SS..THydrogen-bonded Turntrans103.6-11.3-175.300000114.5C452G131-C452 WeakPolarHBondContact O-CB 3.48Å; G131-C452 PolarHBondContact O-N 2.97Å; G131-C452 VanDerWaalsContact O-N 3.13Å
132L80.3Confident54.1Low18 Ų1892.5 Ų92.59%0.09453%0.534CS..SBendtrans-92.2167.6172.3-64.3169.2000110.8F134 P451 C456 K459 F470L132-F134 PolarHBondContact O-N 3.26Å; L132-P451 HydrophobicContact CD2-CB 4Å; L132-C456 WeakPolarHBondContact CB-O 3.32Å; L132-C456 HydrophobicContact CD2-CB 4.02Å; L132-K459 HydrophobicContact CD1-CB 4.29Å; L132-K459 HydrophobicContact CD1-CD 4.48Å; L132-K459 HydrophobicContact CD1-CG 4.17Å; L132-K459 HydrophobicContact CD2-CB 4.42Å; L132-F470 HydrophobicContact CD2-CD1 3.74Å; L132-F470 HydrophobicContact CD2-CE1 4.09Å
133C82.2Confident54.5Low5 Ų591.3 Ų91.33%0.03453%0.531CS..  trans-68.7122.4175.7171.70000110.9C430 C456 L457C133-C430 HydrophobicContact CB-CB 3.68Å; C133-C430 WeakPolarHBondContact CB-SG 3.29Å; C133-C430 WeakPolarHBondContact SG-CB 3.36Å; C133-C430 CovalentContact SG-SG 2.02Å; C133-C430 PolarHBondContact SG-SG 3.33Å; C133-C456 WeakPolarHBondContact CB-O 3.45Å; C133-C456 PolarHBondContact N-O 3.06Å; C133-L457 HydrophobicContact CB-CD2 4.36Å; C133-L457 WeakPolarHBondContact O-CD2 3.44Å
134F78.3Confident54.7Low109 Ų10996.3 Ų96.348%0.47855%0.552SS.*  trans-124.4143.3174.5-159.4-100000111.4L132 S136 C430L132-F134 PolarHBondContact O-N 3.26Å; F134-S136 WeakPolarHBondContact CD1-OG 3.48Å; F134-S136 WeakPolarHBondContact CE1-OG 3.2Å; F134-C430 CarbonylContact O-C 3.54Å; F134-C430 VanDerWaalsContact O-C 3.26Å; F134-C430 VanDerWaalsContact O-CA 3.28Å; F134-C430 WeakPolarHBondContact O-CA 3.32Å; F134-C430 VanDerWaalsContact O-O 3.13Å
135S63.6Low55.1Low88 Ų8899 Ų9962%0.61556%0.555SS**SBendtrans-88.71.7-174.7-58.40000115
136S57.5Low55.4Low67 Ų67102.8 Ų102.847%0.46956%0.559SS.*SBendtrans-111.2136169.784.30000111F134 P138F134-S136 WeakPolarHBondContact CD1-OG 3.48Å; F134-S136 WeakPolarHBondContact CE1-OG 3.2Å; S136-P138 WeakPolarHBondContact O-CD 3.38Å
137L50.3Low56.1Low156 Ų156100.9 Ų100.982%0.81755%0.545SS*.  trans-58118.1173.9-117.672.8000109.9S139L137-S139 PolarHBondContact O-N 3.05Å
138P50Low56.6Low95 Ų9596.2 Ų96.262%0.61752%0.521SS*.  trans-72.2130.2164.7-10.328.1000108.8S136S136-P138 WeakPolarHBondContact O-CD 3.38Å
139S43Very low57Low102 Ų10294.3 Ų94.371%0.71351%0.511SS*.  trans-34.7141.4171.5164.60000114.8L137 Q141L137-S139 PolarHBondContact O-N 3.05Å; S139-Q141 PolarHBondContact O-N 3.41Å
140N45Very low57.3Low149 Ų14990.6 Ų90.680%0.79750%0.501SS*.  trans-687.5157.6-79.5-20.2000113.8T142N140-T142 PolarHBondContact O-N 3.25Å
141Q49.8Very low57.5Low124 Ų12492.6 Ų92.658%0.57951%0.507SS*.  trans-68.194162.9-86.1-177.5-2.900106.8S139 C143S139-Q141 PolarHBondContact O-N 3.41Å; Q141-C143 VanDerWaalsContact C-N 3.35Å; Q141-C143 PolarHBondContact O-N 2.72Å
142T48.5Very low57.6Low110 Ų11098.1 Ų98.168%0.67552%0.518SS*.  trans-62.4103.8161.846.40000106.5N140 H144N140-T142 PolarHBondContact O-N 3.25Å; T142-H144 PolarHBondContact O-N 3.18Å
143C58.3Low57.7Low51 Ų51100.2 Ų100.235%0.34554%0.539SS..  trans-50.1117.6165.9157.60000107.4Q141 K145 C568Q141-C143 VanDerWaalsContact C-N 3.35Å; Q141-C143 PolarHBondContact O-N 2.72Å; C143-K145 VanDerWaalsContact C-N 3.25Å; C143-K145 PolarHBondContact O-N 2.67Å; C143-C568 HydrophobicContact CB-CB 3.77Å; C143-C568 WeakPolarHBondContact CB-SG 3.46Å; C143-C568 WeakPolarHBondContact SG-CB 3.2Å; C143-C568 CovalentContact SG-SG 2Å; C143-C568 PolarHBondContact SG-SG 2.86Å
144H54.2Low58.1Low143 Ų143100.2 Ų100.266%0.66254%0.539SS*.  trans-67.290.4172.1-85.3-73000108.3T142 K146 D147T142-H144 PolarHBondContact O-N 3.18Å; H144-K146 PolarHBondContact O-N 3.09Å; H144-D147 PolarHBondContact O-N 3.16Å; H144-D147 VanDerWaalsContact O-N 3.15Å
145K50.9Low58.7Low162 Ų16297.1 Ų97.170%0.70452%0.524SS*.Hα-helixtrans-48.3-22.1173.3-90.8-179.7172.9177.50113.7C143 D147 S148 D149C143-K145 VanDerWaalsContact C-N 3.25Å; C143-K145 PolarHBondContact O-N 2.67Å; K145-D147 VanDerWaalsContact C-N 3.28Å; K145-D147 PolarHBondContact O-N 3.08Å; K145-S148 WeakPolarHBondContact O-CB 3.3Å; K145-S148 PolarHBondContact O-N 3.27Å; K145-S148 PolarHBondContact O-OG 3.48Å; K145-D149 PolarHBondContact O-N 2.86Å
146K48Very low60.2Low174 Ų17496.4 Ų96.476%0.75752%0.517SS*.Hα-helixtrans-60.1-31.9-180-142.7171.4-174.2178.20113.5H144H144-K146 PolarHBondContact O-N 3.09Å
147D52.3Low61.9Low85 Ų8594.9 Ų94.946%0.45550%0.503SS..Hα-helixtrans-77.7-25.7173.6-75.9-22000112.3H144 K145 T150 Q151H144-D147 PolarHBondContact O-N 3.16Å; H144-D147 VanDerWaalsContact O-N 3.15Å; K145-D147 VanDerWaalsContact C-N 3.28Å; K145-D147 PolarHBondContact O-N 3.08Å; D147-T150 PolarHBondContact O-OG1 2.94Å; D147-Q151 WeakPolarHBondContact O-CG 3.08Å; D147-Q151 PolarHBondContact O-N 3.2Å
148S53.3Low64Low26 Ų2687.4 Ų87.418%0.18247%0.465CS..Hα-helixtrans-71.2-39.4178.678.10000112.1K145 T150 Q151 W152K145-S148 WeakPolarHBondContact O-CB 3.3Å; K145-S148 PolarHBondContact O-N 3.27Å; K145-S148 PolarHBondContact O-OG 3.48Å; S148-T150 VanDerWaalsContact C-N 3.35Å; S148-T150 PolarHBondContact O-N 3.28Å; S148-Q151 WeakPolarHBondContact O-CB 3.32Å; S148-Q151 PolarHBondContact O-N 2.95Å; S148-Q151 VanDerWaalsContact O-N 3.15Å; S148-W152 PolarHBondContact O-N 3.43Å; S148-W152 VanDerWaalsContact O-N 3.09Å
149D54Low66.2Low114 Ų11484.2 Ų84.261%0.6144%0.442SS*.Hα-helixtrans-65-36.5-176.4-68.9-23.6000112.7K145K145-D149 PolarHBondContact O-N 2.86Å
150T58.2Low68.8Low66 Ų6683.2 Ų83.241%0.40543%0.428SS..Hα-helixtrans-72.7-35174.337.70000112.1D147 S148 A153 V154D147-T150 PolarHBondContact O-OG1 2.94Å; S148-T150 VanDerWaalsContact C-N 3.35Å; S148-T150 PolarHBondContact O-N 3.28Å; T150-A153 PolarHBondContact O-N 3.47Å; T150-V154 WeakPolarHBondContact O-CG2 3.34Å
151Q63Low71.2Confident70 Ų7076.1 Ų76.133%0.32739%0.39SS..Hα-helixtrans-66.4-35.1177.3-64.6-101.3-4000112.5D147 S148 A153 V154D147-Q151 WeakPolarHBondContact O-CG 3.08Å; D147-Q151 PolarHBondContact O-N 3.2Å; S148-Q151 WeakPolarHBondContact O-CB 3.32Å; S148-Q151 PolarHBondContact O-N 2.95Å; S148-Q151 VanDerWaalsContact O-N 3.15Å; Q151-A153 VanDerWaalsContact C-N 3.31Å; Q151-A153 PolarHBondContact O-N 3.34Å; Q151-V154 PolarHBondContact O-N 2.97Å
152W69.4Low73.4Confident146 Ų14670.3 Ų70.355%0.55336%0.363SS*.Hα-helixtrans-63.8-32.8177.1-75.4109.4000113.4S148 P156S148-W152 PolarHBondContact O-N 3.43Å; S148-W152 VanDerWaalsContact O-N 3.09Å; W152-P156 WeakPolarHBondContact O-CD 3.37Å
153A82.6Confident75.7Confident63 Ų6367.4 Ų67.452%0.52134%0.343SS..Hα-helixtrans-76.8-21.6179.900000113.5T150 Q151 P156 L157T150-A153 PolarHBondContact O-N 3.47Å; Q151-A153 VanDerWaalsContact C-N 3.31Å; Q151-A153 PolarHBondContact O-N 3.34Å; A153-P156 WeakPolarHBondContact O-CD 3.45Å; A153-L157 WeakPolarHBondContact O-CB 3.46Å; A153-L157 PolarHBondContact O-N 2.88Å
154V89.8Confident77.5Confident5 Ų567 Ų673%0.0334%0.337CS..Hα-helixtrans-66.6-45.2-175.8170.70000112.3Y54 P109 T150 Q151 L157 L158Y54-V154 HydrophobicContact CD1-CB 4.17Å; Y54-V154 HydrophobicContact CD1-CG1 3.85Å; Y54-V154 HydrophobicContact CD1-CG2 4.07Å; Y54-V154 HydrophobicContact CD2-CG1 3.88Å; Y54-V154 HydrophobicContact CE1-CB 4.18Å; Y54-V154 HydrophobicContact CE1-CG1 3.82Å; Y54-V154 HydrophobicContact CE1-CG2 3.68Å; Y54-V154 HydrophobicContact CE2-CG1 3.82Å; Y54-V154 HydrophobicContact CG-CG1 3.89Å; P109-V154 HydrophobicContact CB-CB 4.41Å; P109-V154 HydrophobicContact CB-CG1 3.7Å; P109-V154 HydrophobicContact CB-CG2 4.07Å; P109-V154 HydrophobicContact CG-CG1 4.13Å; T150-V154 WeakPolarHBondContact O-CG2 3.34Å; Q151-V154 PolarHBondContact O-N 2.97Å; V154-L157 WeakPolarHBondContact O-CB 3.36Å; V154-L157 PolarHBondContact O-N 2.8Å; V154-L158 HydrophobicContact CG1-CD1 3.73Å; V154-L158 HydrophobicContact CG1-CG 4.15Å; V154-L158 WeakPolarHBondContact O-CG 3.17Å; V154-L158 PolarHBondContact O-N 3.06Å
155Y91.8Very high79.5Confident43 Ų4360.3 Ų60.317%0.16931%0.306CS..Hα-helixtrans-64.6-47.3-176-176.8-107.4000112.9L56 K60 L64 L157 L158 L159L56-Y155 HydrophobicContact CD1-CD2 3.9Å; L56-Y155 HydrophobicContact CD1-CE2 4.32Å; L56-Y155 HydrophobicContact CD2-CD2 3.84Å; L56-Y155 HydrophobicContact CD2-CG 4.34Å; K60-Y155 HydrophobicContact CB-CE2 3.97Å; K60-Y155 PolarHBondContact O-OH 3.3Å; L64-Y155 HydrophobicContact CB-CE2 4.16Å; Y155-L157 VanDerWaalsContact C-N 3.29Å; Y155-L157 PolarHBondContact O-N 3.08Å; Y155-L158 PolarHBondContact O-N 3.24Å; Y155-L159 HydrophobicContact CD1-CD1 3.94Å; Y155-L159 HydrophobicContact CE1-CD1 3.53Å; Y155-L159 HydrophobicContact CE1-CG 4.25Å; Y155-L159 WeakPolarHBondContact O-CG 3.44Å; Y155-L159 PolarHBondContact O-N 3.16Å
156P93.7Very high81.6Confident73 Ų7352.6 Ų52.647%0.47427%0.273SS..Hα-helixtrans-57.8-37.6170.5-25.134.5000113.7W152 A153 L159 L160W152-P156 WeakPolarHBondContact O-CD 3.37Å; A153-P156 WeakPolarHBondContact O-CD 3.45Å; P156-L159 PolarHBondContact O-N 3.45Å; P156-L160 WeakPolarHBondContact O-CB 3.41Å; P156-L160 PolarHBondContact O-N 3.29Å
157L94.3Very high83.8Confident35 Ų3546.8 Ų46.818%0.18325%0.25CC..Hα-helixtrans-65.1-43.5178.3-175.660.7000112L105 V108 P109 L112 A153 V154 Y155 L160 G161L105-L157 HydrophobicContact CD1-CD1 3.55Å; L105-L157 HydrophobicContact CD1-CG 4.49Å; L105-L157 HydrophobicContact CD2-CD1 4.25Å; L105-L157 HydrophobicContact CG-CD1 3.84Å; V108-L157 HydrophobicContact CB-CD2 4.31Å; V108-L157 HydrophobicContact CG1-CD2 4Å; P109-L157 HydrophobicContact CG-CD2 3.89Å; P109-L157 HydrophobicContact CG-CG 4.36Å; L112-L157 HydrophobicContact CD1-CD2 4.06Å; A153-L157 WeakPolarHBondContact O-CB 3.46Å; A153-L157 PolarHBondContact O-N 2.88Å; V154-L157 WeakPolarHBondContact O-CB 3.36Å; V154-L157 PolarHBondContact O-N 2.8Å; Y155-L157 VanDerWaalsContact C-N 3.29Å; Y155-L157 PolarHBondContact O-N 3.08Å; L157-L160 PolarHBondContact O-N 2.92Å; L157-G161 PolarHBondContact O-N 3.34Å
158L95.1Very high85.8Confident0 Ų042.7 Ų42.70%023%0.228CC..Hα-helixtrans-63.9-40.3174.4-68.5170.9000111.5I50 L64 M106 P109 V154 Y155 G161 Q162I50-L158 HydrophobicContact CG2-CD1 3.96Å; L64-L158 HydrophobicContact CD1-CB 3.63Å; L64-L158 HydrophobicContact CD2-CB 4.06Å; L64-L158 HydrophobicContact CD2-CD1 4.03Å; M106-L158 HydrophobicContact CE-CB 4.38Å; M106-L158 HydrophobicContact CE-CD2 3.48Å; M106-L158 VanDerWaalsContact CE-CD2 3.48Å; M106-L158 HydrophobicContact SD-CB 4.38Å; M106-L158 HydrophobicContact SD-CD2 3.95Å; P109-L158 HydrophobicContact CG-CD2 3.86Å; P109-L158 HydrophobicContact CG-CG 4.13Å; V154-L158 HydrophobicContact CG1-CD1 3.73Å; V154-L158 HydrophobicContact CG1-CG 4.15Å; V154-L158 WeakPolarHBondContact O-CG 3.17Å; V154-L158 PolarHBondContact O-N 3.06Å; Y155-L158 PolarHBondContact O-N 3.24Å; L158-G161 PolarHBondContact O-N 3.45Å; L158-Q162 WeakPolarHBondContact O-CG 3.21Å; L158-Q162 PolarHBondContact O-N 3.08Å
159L96.1Very high87.6Confident28 Ų2842 Ų4215%0.14722%0.224CC..Hα-helixtrans-63.5-42.9174.2-73.1174.4000111.7I63 L64 F67 Y155 P156 G161 Q162 L163I63-L159 HydrophobicContact CG2-CD2 4.29Å; L64-L159 HydrophobicContact CB-CD2 4.34Å; L64-L159 HydrophobicContact CD1-CD2 3.91Å; L64-L159 HydrophobicContact CD1-CG 4.26Å; F67-L159 HydrophobicContact CB-CD2 3.88Å; F67-L159 HydrophobicContact CD1-CB 4.03Å; F67-L159 HydrophobicContact CD1-CD2 3.9Å; F67-L159 WeakPolarHBondContact CD1-O 3.34Å; F67-L159 HydrophobicContact CD2-CD2 3.93Å; F67-L159 HydrophobicContact CE1-CB 4Å; F67-L159 HydrophobicContact CE1-CD2 4.37Å; F67-L159 HydrophobicContact CE2-CD2 4.43Å; F67-L159 HydrophobicContact CG-CD2 3.64Å; Y155-L159 HydrophobicContact CD1-CD1 3.94Å; Y155-L159 HydrophobicContact CE1-CD1 3.53Å; Y155-L159 HydrophobicContact CE1-CG 4.25Å; Y155-L159 WeakPolarHBondContact O-CG 3.44Å; Y155-L159 PolarHBondContact O-N 3.16Å; P156-L159 PolarHBondContact O-N 3.45Å; L159-G161 VanDerWaalsContact C-N 3.31Å; L159-G161 PolarHBondContact O-N 3.08Å; L159-Q162 PolarHBondContact O-N 2.96Å; L159-L163 WeakPolarHBondContact O-CB 3.19Å; L159-L163 PolarHBondContact O-N 3.2Å
160L96.2Very high89.4Confident81 Ų8136.7 Ų36.742%0.42420%0.196SC..Hα-helixtrans-60.2-42.9175.5-179.260.8000111.3L105 P156 L157 L163 L164L105-L160 HydrophobicContact CD2-CB 4.37Å; L105-L160 HydrophobicContact CD2-CD2 4.04Å; L105-L160 HydrophobicContact CD2-CG 3.92Å; P156-L160 WeakPolarHBondContact O-CB 3.41Å; P156-L160 PolarHBondContact O-N 3.29Å; L157-L160 PolarHBondContact O-N 2.92Å; L160-L163 PolarHBondContact O-N 3.27Å; L160-L164 HydrophobicContact CD1-CD1 4.29Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 4.2Å; L160-L164 VanDerWaalsContact O-CG 3.32Å; L160-L164 WeakPolarHBondContact O-CG 3.28Å; L160-L164 PolarHBondContact O-N 3.42Å
161G96.6Very high90.9Very high0 Ų034.2 Ų34.20%018%0.18CC..Hα-helixtrans-57-48.817300000112.5A102 L157 L158 L159 L163 L164 L165A102-G161 WeakPolarHBondContact CB-O 3.45Å; L157-G161 PolarHBondContact O-N 3.34Å; L158-G161 PolarHBondContact O-N 3.45Å; L159-G161 VanDerWaalsContact C-N 3.31Å; L159-G161 PolarHBondContact O-N 3.08Å; G161-L163 PolarHBondContact O-N 3.1Å; G161-L164 PolarHBondContact O-N 2.79Å; G161-L165 WeakPolarHBondContact O-CB 3.36Å; G161-L165 PolarHBondContact O-N 3.22Å
162Q96.3Very high92.3Very high2 Ų230.9 Ų30.91%0.00917%0.165CC..Hα-helixtrans-63.8-39.6177.9-70.6-64.5-30.300112.9M43 L64 F67 N68 M106 L158 L159 L165 G166M43-Q162 VanDerWaalsContact CG-NE2 3.31Å; L64-Q162 HydrophobicContact CD1-CG 3.76Å; L64-Q162 WeakPolarHBondContact O-CG 3.44Å; F67-Q162 HydrophobicContact CB-CB 3.96Å; F67-Q162 HydrophobicContact CD1-CB 4.46Å; N68-Q162 WeakPolarHBondContact CA-O 3.27Å; N68-Q162 WeakPolarHBondContact CB-O 3.38Å; M106-Q162 HydrophobicContact CE-CG 4.36Å; M106-Q162 HydrophobicContact SD-CG 4.07Å; L158-Q162 WeakPolarHBondContact O-CG 3.21Å; L158-Q162 PolarHBondContact O-N 3.08Å; L159-Q162 PolarHBondContact O-N 2.96Å; Q162-L165 PolarHBondContact O-N 3.42Å; Q162-G166 PolarHBondContact O-N 3.39Å
163L95.9Very high93.2Very high49 Ų4927.2 Ų27.226%0.25715%0.154SC..Hα-helixtrans-61.4-50.6176.3-177.764.8000111.5F67 L159 L160 G161 L165 G166 I167F67-L163 HydrophobicContact CD1-CB 3.91Å; F67-L163 HydrophobicContact CE1-CB 3.79Å; F67-L163 HydrophobicContact CE1-CD1 4.31Å; F67-L163 HydrophobicContact CE1-CD2 4.41Å; F67-L163 HydrophobicContact CE1-CG 4.39Å; L159-L163 WeakPolarHBondContact O-CB 3.19Å; L159-L163 PolarHBondContact O-N 3.2Å; L160-L163 PolarHBondContact O-N 3.27Å; G161-L163 PolarHBondContact O-N 3.1Å; L163-L165 VanDerWaalsContact C-N 3.3Å; L163-L165 PolarHBondContact O-N 3.4Å; L163-G166 WeakPolarHBondContact O-CA 3.45Å; L163-G166 PolarHBondContact O-N 3.49Å; L163-G166 VanDerWaalsContact O-N 3.13Å; L163-I167 HydrophobicContact CG-CD1 4.14Å; L163-I167 WeakPolarHBondContact O-CG1 3.15Å; L163-I167 PolarHBondContact O-N 3.34Å
164L96.5Very high93.4Very high42 Ų4226.1 Ų26.122%0.2214%0.142CC..Hα-helixtrans-63.2-36.9178.5-67.6177.5000111.8L98 A102 L105 L160 G161 G166 I167 G168L98-L164 HydrophobicContact CD1-CD2 4.35Å; A102-L164 HydrophobicContact CB-CB 3.69Å; L105-L164 HydrophobicContact CD2-CD1 3.97Å; L160-L164 HydrophobicContact CD1-CD1 4.29Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 4.2Å; L160-L164 VanDerWaalsContact O-CG 3.32Å; L160-L164 WeakPolarHBondContact O-CG 3.28Å; L160-L164 PolarHBondContact O-N 3.42Å; G161-L164 PolarHBondContact O-N 2.79Å; L164-G166 VanDerWaalsContact C-N 3.33Å; L164-I167 HydrophobicContact CD2-CD1 4.43Å; L164-I167 PolarHBondContact O-N 2.78Å; L164-G168 PolarHBondContact O-N 3.4Å
165L95.7Very high93.4Very high2 Ų226.1 Ų26.11%0.0114%0.141CC..Hα-helixtrans-61.7-43173.5-176.466.1000111V39 A99 A102 G161 Q162 L163 G168 A169V39-L165 HydrophobicContact CG1-CD1 4.15Å; V39-L165 HydrophobicContact CG1-CD2 3.7Å; A99-L165 HydrophobicContact CB-CD1 3.86Å; A102-L165 HydrophobicContact CB-CB 3.89Å; A102-L165 VanDerWaalsContact CB-N 3.32Å; G161-L165 WeakPolarHBondContact O-CB 3.36Å; G161-L165 PolarHBondContact O-N 3.22Å; Q162-L165 PolarHBondContact O-N 3.42Å; L163-L165 VanDerWaalsContact C-N 3.3Å; L163-L165 PolarHBondContact O-N 3.4Å; L165-G168 PolarHBondContact O-N 3.07Å; L165-A169 VanDerWaalsContact O-CB 3.3Å; L165-A169 WeakPolarHBondContact O-CB 3.5Å; L165-A169 PolarHBondContact O-N 3.49Å
166G94.1Very high93.4Very high1 Ų124.1 Ų24.11%0.0113%0.133CC..Hα-helixtrans-59.2-46.8173.900000113.2N68 Q162 L163 L164 A169 V170N68-G166 WeakPolarHBondContact O-CA 3.41Å; Q162-G166 PolarHBondContact O-N 3.39Å; L163-G166 WeakPolarHBondContact O-CA 3.45Å; L163-G166 PolarHBondContact O-N 3.49Å; L163-G166 VanDerWaalsContact O-N 3.13Å; L164-G166 VanDerWaalsContact C-N 3.33Å; G166-A169 PolarHBondContact O-N 3.36Å; G166-V170 WeakPolarHBondContact O-CG2 3.48Å; G166-V170 PolarHBondContact O-N 3.09Å
167I94.5Very high93Very high51 Ų5123.6 Ų23.626%0.26213%0.126SC..Hα-helixtrans-62.7-47.3176.9-67172000111L75 L98 L163 L164 A169 V170L75-I167 HydrophobicContact CD1-CB 3.96Å; L75-I167 HydrophobicContact CD1-CD1 4.5Å; L75-I167 HydrophobicContact CD1-CG1 3.72Å; L75-I167 HydrophobicContact CD1-CG2 3.56Å; L98-I167 HydrophobicContact CD2-CB 4.16Å; L98-I167 HydrophobicContact CD2-CG2 3.5Å; L98-I167 VanDerWaalsContact CD2-CG2 3.5Å; L163-I167 HydrophobicContact CG-CD1 4.14Å; L163-I167 WeakPolarHBondContact O-CG1 3.15Å; L163-I167 PolarHBondContact O-N 3.34Å; L164-I167 HydrophobicContact CD2-CD1 4.43Å; L164-I167 PolarHBondContact O-N 2.78Å; I167-A169 VanDerWaalsContact C-N 3.3Å; I167-A169 PolarHBondContact O-N 3.02Å; I167-V170 WeakPolarHBondContact O-CG2 3.41Å; I167-V170 PolarHBondContact O-N 3.42Å
168G94.5Very high92.7Very high0 Ų023.6 Ų23.60%013%0.129CC..Hα-helixtrans-66.1-30.6-179.700000113.5G95 L164 L165 P171G95-G168 CarbonylContact C-O 3.16Å; G95-G168 WeakPolarHBondContact CA-O 3.33Å; G95-G168 CarbonylContact O-C 3.42Å; G95-G168 VanDerWaalsContact O-CA 3.23Å; G95-G168 WeakPolarHBondContact O-CA 3.24Å; G95-G168 VanDerWaalsContact O-O 3.11Å; L164-G168 PolarHBondContact O-N 3.4Å; L165-G168 PolarHBondContact O-N 3.07Å; G168-P171 WeakPolarHBondContact O-CD 3.3Å
169A92.3Very high92.5Very high11 Ų1123.6 Ų23.69%0.09113%0.129CC..Hα-helixtrans-75.1-22.6179.600000114.1Q36 L165 G166 I167 I172Q36-A169 HydrophobicContact CG-CB 4.18Å; L165-A169 VanDerWaalsContact O-CB 3.3Å; L165-A169 WeakPolarHBondContact O-CB 3.5Å; L165-A169 PolarHBondContact O-N 3.49Å; G166-A169 PolarHBondContact O-N 3.36Å; I167-A169 VanDerWaalsContact C-N 3.3Å; I167-A169 PolarHBondContact O-N 3.02Å; A169-I172 PolarHBondContact O-N 3.05Å
170V90.6Very high92.2Very high3 Ų322.3 Ų22.32%0.01812%0.122CC..THydrogen-bonded Turntrans-57.3-50-172.8-169.60000114.4N72 L75 I76 V79 G166 I167 I172 P174N72-V170 HydrophobicContact CB-CG2 4.17Å; N72-V170 WeakPolarHBondContact OD1-CG2 3.4Å; L75-V170 HydrophobicContact CB-CB 4.45Å; L75-V170 HydrophobicContact CB-CG1 4.2Å; L75-V170 HydrophobicContact CB-CG2 3.99Å; I76-V170 HydrophobicContact CB-CG1 3.97Å; I76-V170 HydrophobicContact CG1-CG1 4.31Å; V79-V170 HydrophobicContact CB-CG1 3.97Å; V79-V170 HydrophobicContact CG1-CG1 4.41Å; V79-V170 HydrophobicContact CG2-CB 4.27Å; V79-V170 HydrophobicContact CG2-CG1 3.52Å; G166-V170 WeakPolarHBondContact O-CG2 3.48Å; G166-V170 PolarHBondContact O-N 3.09Å; I167-V170 WeakPolarHBondContact O-CG2 3.41Å; I167-V170 PolarHBondContact O-N 3.42Å; V170-I172 VanDerWaalsContact C-N 3.29Å; V170-I172 PolarHBondContact O-N 3.33Å; V170-P174 WeakPolarHBondContact O-CD 3.37Å; V170-P174 WeakPolarHBondContact O-CG 3.46Å
171P90.8Very high91.7Very high13 Ų1322.9 Ų22.98%0.08413%0.125CC..THydrogen-bonded Turntrans-73.9-18.3-177.829.6-36.7000113.4Y91 G168 F175Y91-P171 WeakPolarHBondContact O-CG 3.48Å; G168-P171 WeakPolarHBondContact O-CD 3.3Å; P171-F175 HydrophobicContact CB-CD2 3.69Å; P171-F175 HydrophobicContact CB-CE2 3.83Å; P171-F175 WeakPolarHBondContact O-CB 3.42Å; P171-F175 WeakPolarHBondContact O-CG 3.32Å; P171-F175 PolarHBondContact O-N 3.38Å
172I92.2Very high91.3Very high0 Ų026 Ų260%014%0.143CC..Hα-helixtrans-61.9-62.8-168.7-61.4-180000110.5H29 L32 Q36 I92 A96 A169 V170 G176H29-I172 PolarHBondContact CE1-O 3.13Å; L32-I172 HydrophobicContact CD2-CG2 4Å; L32-I172 HydrophobicContact CG-CG2 4.18Å; Q36-I172 HydrophobicContact CB-CD1 4.39Å; Q36-I172 HydrophobicContact CG-CD1 4.13Å; I92-I172 HydrophobicContact CG2-CG1 4.5Å; A96-I172 HydrophobicContact CB-CD1 4.41Å; A169-I172 PolarHBondContact O-N 3.05Å; V170-I172 VanDerWaalsContact C-N 3.29Å; V170-I172 PolarHBondContact O-N 3.33Å; I172-G176 PolarHBondContact O-N 3.28Å; I172-G176 VanDerWaalsContact O-N 3.11Å
173Q88.1Confident91Very high70 Ų7027.4 Ų27.433%0.32715%0.148SC..Hα-helixtrans-72.3-48.1-171.7-169.2173.65.900113.6F175 G176 I177Q173-F175 PolarHBondContact O-N 3.08Å; Q173-G176 PolarHBondContact O-N 2.93Å; Q173-I177 HydrophobicContact CG-CD1 3.88Å; Q173-I177 WeakPolarHBondContact O-CG1 3.39Å; Q173-I177 PolarHBondContact O-N 3.27Å
174P86.8Confident90.7Very high40 Ų4025.6 Ų25.626%0.2614%0.14SC..Hα-helixtrans-64.9-41.8-178.2-20.734.3000113.3V79 V170 S178V79-P174 HydrophobicContact CG1-CB 4.41Å; V79-P174 HydrophobicContact CG1-CG 4.49Å; V170-P174 WeakPolarHBondContact O-CD 3.37Å; V170-P174 WeakPolarHBondContact O-CG 3.46Å; P174-S178 WeakPolarHBondContact O-CB 3.16Å; P174-S178 PolarHBondContact O-N 3.43Å; P174-S178 VanDerWaalsContact O-N 3.08Å; P174-S178 PolarHBondContact O-OG 2.98Å
175F89.9Confident90.3Very high5 Ų524.1 Ų24.12%0.02213%0.133CC..Hα-helixtrans-73.1-33.4178.7-66.5-16.8000112.3V79 V86 R88 Y91 I92 P171 Q173 S178 Y179V79-F175 HydrophobicContact CB-CZ 4.37Å; V79-F175 HydrophobicContact CG1-CD1 4.05Å; V79-F175 HydrophobicContact CG1-CE1 3.44Å; V79-F175 VanDerWaalsContact CG1-CE1 3.44Å; V79-F175 HydrophobicContact CG1-CE2 4.11Å; V79-F175 HydrophobicContact CG1-CZ 3.51Å; V79-F175 VanDerWaalsContact O-CE1 3.28Å; V79-F175 WeakPolarHBondContact O-CE1 3.44Å; V86-F175 HydrophobicContact CG2-CE2 4.06Å; V86-F175 HydrophobicContact CG2-CZ 3.99Å; R88-F175 HydrophobicContact CB-CB 4.09Å; R88-F175 HydrophobicContact CB-CG 4.33Å; R88-F175 HydrophobicContact CG-CB 4.25Å; R88-F175 HydrophobicContact CG-CD1 4.31Å; R88-F175 HydrophobicContact CG-CG 4.15Å; Y91-F175 HydrophobicContact CD1-CE2 4.46Å; Y91-F175 HydrophobicContact CG-CE2 4.19Å; I92-F175 HydrophobicContact CD1-CB 3.76Å; I92-F175 HydrophobicContact CG1-CB 3.7Å; I92-F175 HydrophobicContact CG1-CD2 4.42Å; P171-F175 HydrophobicContact CB-CD2 3.69Å; P171-F175 HydrophobicContact CB-CE2 3.83Å; P171-F175 WeakPolarHBondContact O-CB 3.42Å; P171-F175 WeakPolarHBondContact O-CG 3.32Å; P171-F175 PolarHBondContact O-N 3.38Å; Q173-F175 PolarHBondContact O-N 3.08Å; F175-S178 WeakPolarHBondContact CA-OG 3.48Å; F175-S178 PolarHBondContact O-OG 3.33Å; F175-Y179 WeakPolarHBondContact O-CB 3.2Å; F175-Y179 PolarHBondContact O-N 3.28Å
176G90.6Very high89.4Confident0 Ų034.8 Ų34.80%017%0.173CC..Hα-helixtrans-67.6-44175.200000113H29 I172 Q173 Y179 I180H29-G176 WeakPolarHBondContact NE2-CA 3.24Å; I172-G176 PolarHBondContact O-N 3.28Å; I172-G176 VanDerWaalsContact O-N 3.11Å; Q173-G176 PolarHBondContact O-N 2.93Å; G176-Y179 PolarHBondContact O-N 2.74Å; G176-I180 WeakPolarHBondContact O-CD1 3.35Å; G176-I180 WeakPolarHBondContact O-CG1 3.4Å; G176-I180 PolarHBondContact O-N 3.26Å
177I87Confident88.7Confident62 Ų6245 Ų4532%0.31821%0.212SC..Hα-helixtrans-59.6-52.6175-70.1170.3000110.6Q173 Y179 I180 D181 L193Q173-I177 HydrophobicContact CG-CD1 3.88Å; Q173-I177 WeakPolarHBondContact O-CG1 3.39Å; Q173-I177 PolarHBondContact O-N 3.27Å; I177-Y179 VanDerWaalsContact C-N 3.33Å; I177-Y179 PolarHBondContact O-N 2.82Å; I177-I180 PolarHBondContact O-N 2.95Å; I177-D181 PolarHBondContact O-N 2.9Å; I177-L193 HydrophobicContact CB-CD2 4.21Å; I177-L193 HydrophobicContact CG1-CD2 4.15Å; I177-L193 HydrophobicContact CG2-CD2 3.83Å
178S87.9Confident88.1Confident35 Ų3544.9 Ų44.925%0.24521%0.212CC..Hα-helixtrans-64.5-35.4-179.555.80000112.9R88 P174 F175 D182R88-S178 PolarHBondContact NH1-O 3.4Å; R88-S178 PolarHBondContact NH1-OG 3.11Å; P174-S178 WeakPolarHBondContact O-CB 3.16Å; P174-S178 PolarHBondContact O-N 3.43Å; P174-S178 VanDerWaalsContact O-N 3.08Å; P174-S178 PolarHBondContact O-OG 2.98Å; F175-S178 WeakPolarHBondContact CA-OG 3.48Å; F175-S178 PolarHBondContact O-OG 3.33Å; S178-D182 WeakPolarHBondContact O-CB 3.41Å; S178-D182 VanDerWaalsContact O-CG 3.23Å; S178-D182 PolarHBondContact O-N 3.35Å; S178-D182 VanDerWaalsContact O-N 3.08Å
179Y89.5Confident87.5Confident1 Ų145.3 Ų45.30%0.00421%0.214CC..Hα-helixtrans-67.5-39175.6-167-87.1000111.5F25 R88 P89 F175 G176 I177 Y183 P264 M267F25-Y179 AromaticContact CD1-CD1 3.79Å; F25-Y179 HydrophobicContact CD1-CD1 3.79Å; F25-Y179 HydrophobicContact CD1-CE1 4.31Å; F25-Y179 AromaticContact CD2-CD1 3.87Å; F25-Y179 HydrophobicContact CD2-CD1 3.87Å; F25-Y179 AromaticContact CD2-CE1 3.76Å; F25-Y179 HydrophobicContact CD2-CE1 3.76Å; F25-Y179 AromaticContact CE1-CD1 3.56Å; F25-Y179 HydrophobicContact CE1-CD1 3.56Å; F25-Y179 HydrophobicContact CE1-CE1 4.4Å; F25-Y179 HydrophobicContact CE1-CG 4.17Å; F25-Y179 AromaticContact CE2-CD1 3.62Å; F25-Y179 HydrophobicContact CE2-CD1 3.62Å; F25-Y179 AromaticContact CE2-CE1 3.83Å; F25-Y179 HydrophobicContact CE2-CE1 3.83Å; F25-Y179 HydrophobicContact CE2-CG 4.19Å; F25-Y179 AromaticContact CG-CD1 3.95Å; F25-Y179 HydrophobicContact CG-CD1 3.95Å; F25-Y179 HydrophobicContact CG-CE1 4Å; F25-Y179 AromaticContact CZ-CD1 3.45Å; F25-Y179 HydrophobicContact CZ-CD1 3.45Å; F25-Y179 VanDerWaalsContact CZ-CD1 3.45Å; F25-Y179 HydrophobicContact CZ-CE1 4.16Å; F25-Y179 AromaticContact CZ-CG 3.82Å; F25-Y179 HydrophobicContact CZ-CG 3.82Å; R88-Y179 HydrophobicContact CB-CD2 4.18Å; P89-Y179 HydrophobicContact CG-CD2 3.97Å; P89-Y179 HydrophobicContact CG-CE2 3.49Å; P89-Y179 VanDerWaalsContact CG-CE2 3.49Å; F175-Y179 WeakPolarHBondContact O-CB 3.2Å; F175-Y179 PolarHBondContact O-N 3.28Å; G176-Y179 PolarHBondContact O-N 2.74Å; I177-Y179 VanDerWaalsContact C-N 3.33Å; I177-Y179 PolarHBondContact O-N 2.82Å; Y179-Y183 AromaticContact CD1-CD2 3.81Å; Y179-Y183 HydrophobicContact CD1-CD2 3.81Å; Y179-Y183 HydrophobicContact CD1-CE2 4.24Å; Y179-Y183 HydrophobicContact CD2-CD2 4.04Å; Y179-Y183 AromaticContact CD2-CE2 3.6Å; Y179-Y183 HydrophobicContact CD2-CE2 3.6Å; Y179-Y183 AromaticContact CE1-CD2 3.68Å; Y179-Y183 HydrophobicContact CE1-CD2 3.68Å; Y179-Y183 HydrophobicContact CE1-CE2 4.06Å; Y179-Y183 AromaticContact CE2-CD2 3.93Å; Y179-Y183 HydrophobicContact CE2-CD2 3.93Å; Y179-Y183 AromaticContact CE2-CE2 3.4Å; Y179-Y183 HydrophobicContact CE2-CE2 3.4Å; Y179-Y183 VanDerWaalsContact CE2-CE2 3.4Å; Y179-Y183 AromaticContact CG-CD2 3.99Å; Y179-Y183 HydrophobicContact CG-CD2 3.99Å; Y179-Y183 HydrophobicContact CG-CE2 4.03Å; Y179-Y183 AromaticContact CZ-CD2 3.74Å; Y179-Y183 AromaticContact CZ-CE2 3.64Å; Y179-Y183 WeakPolarHBondContact O-CD2 3.37Å; Y179-Y183 PolarHBondContact O-N 3.36Å; Y179-P264 PolarHBondContact OH-O 3Å; Y179-P264 VanDerWaalsContact OH-O 3.08Å; Y179-M267 HydrophobicContact CE1-CB 4.45Å; Y179-M267 HydrophobicContact CE1-CE 4.03Å; Y179-M267 HydrophobicContact CE1-SD 4.43Å
180I90.1Very high86.8Confident0 Ų048.8 Ų48.80%024%0.236CC..Hα-helixtrans-65.9-44175.8-71.9162.4000111I22 F25 V26 G176 I177 D182 Y183 A184 Y192 L193 L196I22-I180 HydrophobicContact CD1-CG1 4.41Å; F25-I180 HydrophobicContact CD1-CD1 4.18Å; F25-I180 HydrophobicContact CD1-CG1 3.73Å; F25-I180 HydrophobicContact CE1-CD1 4.11Å; F25-I180 HydrophobicContact CE1-CG1 3.78Å; V26-I180 HydrophobicContact CG2-CD1 3.85Å; V26-I180 HydrophobicContact CG2-CG1 3.92Å; V26-I180 HydrophobicContact CG2-CG2 4.4Å; G176-I180 WeakPolarHBondContact O-CD1 3.35Å; G176-I180 WeakPolarHBondContact O-CG1 3.4Å; G176-I180 PolarHBondContact O-N 3.26Å; I177-I180 PolarHBondContact O-N 2.95Å; I180-D182 VanDerWaalsContact C-N 3.33Å; I180-D182 PolarHBondContact O-N 2.92Å; I180-Y183 PolarHBondContact O-N 3.38Å; I180-A184 HydrophobicContact CG2-CB 4.25Å; I180-A184 WeakPolarHBondContact O-CB 3.42Å; I180-A184 PolarHBondContact O-N 2.88Å; I180-Y192 HydrophobicContact CG2-CD2 4.15Å; I180-Y192 HydrophobicContact CG2-CG 4.47Å; I180-L193 HydrophobicContact CB-CD2 4.43Å; I180-L193 HydrophobicContact CG2-CD2 4.2Å; I180-L196 HydrophobicContact CD1-CD1 3.1Å
181D86.4Confident86.4Confident93 Ų9353.7 Ų53.750%0.49726%0.262SS..Hα-helixtrans-64.8-36.6-178.7-162.153.9000112.8I177 Y183 S189I177-D181 PolarHBondContact O-N 2.9Å; D181-Y183 VanDerWaalsContact C-N 3.34Å; D181-Y183 PolarHBondContact O-N 3.03Å; D181-S189 PolarHBondContact OD1-OG 2.89Å
182D87.4Confident86.3Confident67 Ų6754 Ų5436%0.35826%0.261SS..Hα-helixtrans-69.6-28.2179.7-76-12.2000113.7R88 S178 I180 K269R88-D182 IonicContact CZ-OD2 3.13Å; R88-D182 IonicContact NH1-OD2 2.65Å; R88-D182 PolarHBondContact NH1-OD2 3.46Å; R88-D182 IonicContact NH2-OD2 2.76Å; R88-D182 PolarHBondContact NH2-OD2 2.94Å; S178-D182 WeakPolarHBondContact O-CB 3.41Å; S178-D182 VanDerWaalsContact O-CG 3.23Å; S178-D182 PolarHBondContact O-N 3.35Å; S178-D182 VanDerWaalsContact O-N 3.08Å; I180-D182 VanDerWaalsContact C-N 3.33Å; I180-D182 PolarHBondContact O-N 2.92Å; D182-K269 WeakPolarHBondContact O-CE 3.12Å
183Y89.9Confident85.7Confident30 Ų3055.9 Ų55.912%0.11827%0.271CS..Hα-helixtrans-119.1-17.2-169.5-60.5-63000115.4Y179 I180 D181 E266 M267 K269 E270Y179-Y183 AromaticContact CD1-CD2 3.81Å; Y179-Y183 HydrophobicContact CD1-CD2 3.81Å; Y179-Y183 HydrophobicContact CD1-CE2 4.24Å; Y179-Y183 HydrophobicContact CD2-CD2 4.04Å; Y179-Y183 AromaticContact CD2-CE2 3.6Å; Y179-Y183 HydrophobicContact CD2-CE2 3.6Å; Y179-Y183 AromaticContact CE1-CD2 3.68Å; Y179-Y183 HydrophobicContact CE1-CD2 3.68Å; Y179-Y183 HydrophobicContact CE1-CE2 4.06Å; Y179-Y183 AromaticContact CE2-CD2 3.93Å; Y179-Y183 HydrophobicContact CE2-CD2 3.93Å; Y179-Y183 AromaticContact CE2-CE2 3.4Å; Y179-Y183 HydrophobicContact CE2-CE2 3.4Å; Y179-Y183 VanDerWaalsContact CE2-CE2 3.4Å; Y179-Y183 AromaticContact CG-CD2 3.99Å; Y179-Y183 HydrophobicContact CG-CD2 3.99Å; Y179-Y183 HydrophobicContact CG-CE2 4.03Å; Y179-Y183 AromaticContact CZ-CD2 3.74Å; Y179-Y183 AromaticContact CZ-CE2 3.64Å; Y179-Y183 WeakPolarHBondContact O-CD2 3.37Å; Y179-Y183 PolarHBondContact O-N 3.36Å; I180-Y183 PolarHBondContact O-N 3.38Å; D181-Y183 VanDerWaalsContact C-N 3.34Å; D181-Y183 PolarHBondContact O-N 3.03Å; Y183-E266 HydrophobicContact CE1-CB 4.42Å; Y183-E266 VanDerWaalsContact OH-CA 3.3Å; Y183-E266 WeakPolarHBondContact OH-CA 3.19Å; Y183-M267 HydrophobicContact CD1-CB 3.87Å; Y183-M267 WeakPolarHBondContact CD1-O 2.87Å; Y183-M267 HydrophobicContact CD2-CB 4.01Å; Y183-M267 HydrophobicContact CE1-CB 4.28Å; Y183-M267 VanDerWaalsContact CE1-N 3.34Å; Y183-M267 WeakPolarHBondContact CE1-O 3.42Å; Y183-M267 HydrophobicContact CE2-CB 4.45Å; Y183-M267 HydrophobicContact CG-CB 3.75Å; Y183-K269 HydrophobicContact CD1-CG 4.37Å; Y183-E270 PolarHBondContact O-N 3.42Å
184A89.2Confident85.1Confident12 Ų1254.3 Ų54.310%0.09927%0.274CS..SBendtrans-78152.6172.800000111.3I22 I180 Y192I22-A184 HydrophobicContact CG1-CB 4.22Å; I180-A184 HydrophobicContact CG2-CB 4.25Å; I180-A184 WeakPolarHBondContact O-CB 3.42Å; I180-A184 PolarHBondContact O-N 2.88Å; A184-Y192 HydrophobicContact CB-CD2 3.73Å; A184-Y192 HydrophobicContact CB-CE2 3.96Å
185S88.2Confident85Confident11 Ų1155.9 Ų55.98%0.07728%0.279CS..  trans-64151.1171.859.40000110.5R187 N188 S189 E270S185-R187 PolarHBondContact O-N 3.49Å; S185-R187 VanDerWaalsContact O-N 3.09Å; S185-N188 PolarHBondContact O-N 3.31Å; S185-N188 VanDerWaalsContact OG-CB 3.29Å; S185-N188 WeakPolarHBondContact OG-CB 3.41Å; S185-N188 VanDerWaalsContact OG-CG 3.3Å; S185-N188 PolarHBondContact OG-N 2.88Å; S185-N188 PolarHBondContact OG-ND2 2.71Å; S185-S189 PolarHBondContact O-N 3.21Å; S185-E270 WeakPolarHBondContact CB-OE2 3.43Å; S185-E270 PolarHBondContact N-OE2 3.04Å; S185-E270 VanDerWaalsContact N-OE2 3.13Å; S185-E270 PolarHBondContact OG-OE2 3.43Å
186R78Confident84.8Confident225 Ų22555.9 Ų55.985%0.84928%0.279SS*.THydrogen-bonded Turntrans-58.2-29.1179.9-71.5-158.9-175.7-136.45.8112.7P190R186-P190 WeakPolarHBondContact O-CD 3.41Å
187R79.6Confident84.3Confident216 Ų21660.3 Ų60.382%0.81530%0.302SS*.THydrogen-bonded Turntrans-73.5-38.3176.7-171.5176.3177.8177.9-0.8112.9S185S185-R187 PolarHBondContact O-N 3.49Å; S185-R187 VanDerWaalsContact O-N 3.09Å
188N81.9Confident83.9Confident49 Ų4959.6 Ų59.626%0.26231%0.306SS..THydrogen-bonded Turntrans-94.5-23.7-175.5-63.6-23.1000114.1S185 L191 Y192 E270S185-N188 PolarHBondContact O-N 3.31Å; S185-N188 VanDerWaalsContact OG-CB 3.29Å; S185-N188 WeakPolarHBondContact OG-CB 3.41Å; S185-N188 VanDerWaalsContact OG-CG 3.3Å; S185-N188 PolarHBondContact OG-N 2.88Å; S185-N188 PolarHBondContact OG-ND2 2.71Å; N188-L191 WeakPolarHBondContact O-CB 3.49Å; N188-L191 PolarHBondContact O-N 3.05Å; N188-Y192 HydrophobicContact CB-CD2 4.45Å; N188-Y192 HydrophobicContact CB-CE2 3.94Å; N188-Y192 PolarHBondContact O-N 3.39Å; N188-Y192 VanDerWaalsContact O-N 3.08Å; N188-E270 WeakPolarHBondContact CB-OE2 3.4Å; N188-E270 VanDerWaalsContact ND2-CD 3.29Å; N188-E270 PolarHBondContact ND2-OE1 3.28Å; N188-E270 VanDerWaalsContact ND2-OE1 3.11Å; N188-E270 PolarHBondContact ND2-OE2 3.39Å
189S81.1Confident83.9Confident8 Ų859.6 Ų59.66%0.05630%0.303CS..Hα-helixtrans-49.8-48.5179.1173.20000112.7D181 S185 L191 Y192 L193D181-S189 PolarHBondContact OD1-OG 2.89Å; S185-S189 PolarHBondContact O-N 3.21Å; S189-L191 VanDerWaalsContact C-N 3.3Å; S189-L191 PolarHBondContact O-N 3.39Å; S189-Y192 PolarHBondContact O-N 3.36Å; S189-L193 WeakPolarHBondContact O-CG 3.43Å; S189-L193 PolarHBondContact O-N 3.48Å
190P77.6Confident83.6Confident84 Ų8461 Ų6155%0.54531%0.311SS..Hα-helixtrans-61.2-34.7178.4-23.834.7000114.1R186 G194R186-P190 WeakPolarHBondContact O-CD 3.41Å; P190-G194 PolarHBondContact O-N 3.39Å
191L83.3Confident83.2Confident107 Ų10763.2 Ų63.256%0.5633%0.327SS*.Hα-helixtrans-67.9-46.3177.4177.365.6000110.7N188 S189 G194 I195N188-L191 WeakPolarHBondContact O-CB 3.49Å; N188-L191 PolarHBondContact O-N 3.05Å; S189-L191 VanDerWaalsContact C-N 3.3Å; S189-L191 PolarHBondContact O-N 3.39Å; L191-G194 PolarHBondContact O-N 3.3Å; L191-I195 HydrophobicContact CG-CD1 4.36Å; L191-I195 WeakPolarHBondContact O-CG1 3.2Å; L191-I195 PolarHBondContact O-N 3.04Å
192Y86.7Confident83.3Confident19 Ų1962.1 Ų62.18%0.07532%0.32CS..Hα-helixtrans-63.8-42.3178.8-63.7-21.1000112.4I22 K23 V26 I180 A184 N188 S189 G194 I195 L196 E270I22-Y192 HydrophobicContact CG1-CE2 4.35Å; I22-Y192 HydrophobicContact CG2-CE2 4.02Å; K23-Y192 WeakPolarHBondContact CG-OH 3.49Å; V26-Y192 HydrophobicContact CG1-CD1 4.22Å; V26-Y192 HydrophobicContact CG1-CG 4.27Å; V26-Y192 HydrophobicContact CG2-CD1 4.24Å; V26-Y192 HydrophobicContact CG2-CD2 3.78Å; V26-Y192 HydrophobicContact CG2-CE2 4.39Å; V26-Y192 HydrophobicContact CG2-CG 3.69Å; I180-Y192 HydrophobicContact CG2-CD2 4.15Å; I180-Y192 HydrophobicContact CG2-CG 4.47Å; A184-Y192 HydrophobicContact CB-CD2 3.73Å; A184-Y192 HydrophobicContact CB-CE2 3.96Å; N188-Y192 HydrophobicContact CB-CD2 4.45Å; N188-Y192 HydrophobicContact CB-CE2 3.94Å; N188-Y192 PolarHBondContact O-N 3.39Å; N188-Y192 VanDerWaalsContact O-N 3.08Å; S189-Y192 PolarHBondContact O-N 3.36Å; Y192-G194 VanDerWaalsContact C-N 3.32Å; Y192-G194 PolarHBondContact O-N 3.45Å; Y192-I195 PolarHBondContact O-N 3.09Å; Y192-L196 PolarHBondContact O-N 3.49Å; Y192-L196 VanDerWaalsContact O-N 3.11Å; Y192-E270 PolarHBondContact OH-OE1 3.44Å
193L81.1Confident83.5Confident40 Ų4059 Ų5921%0.20930%0.303CS..Hα-helixtrans-64.6-37.3173.9-64.9179.1000111.8I177 I180 S189 L196 L197I177-L193 HydrophobicContact CB-CD2 4.21Å; I177-L193 HydrophobicContact CG1-CD2 4.15Å; I177-L193 HydrophobicContact CG2-CD2 3.83Å; I180-L193 HydrophobicContact CB-CD2 4.43Å; I180-L193 HydrophobicContact CG2-CD2 4.2Å; S189-L193 WeakPolarHBondContact O-CG 3.43Å; S189-L193 PolarHBondContact O-N 3.48Å; L193-L196 WeakPolarHBondContact O-CB 3.37Å; L193-L196 PolarHBondContact O-N 3.02Å; L193-L197 WeakPolarHBondContact O-CG 3.31Å; L193-L197 PolarHBondContact O-N 3.35Å
194G75.6Confident83.6Confident37 Ų3758.9 Ų58.938%0.38131%0.307SS..Hα-helixtrans-61.2-43.9173.800000113.2P190 L191 Y192 L196 L197 A198P190-G194 PolarHBondContact O-N 3.39Å; L191-G194 PolarHBondContact O-N 3.3Å; Y192-G194 VanDerWaalsContact C-N 3.32Å; Y192-G194 PolarHBondContact O-N 3.45Å; G194-L196 VanDerWaalsContact C-N 3.34Å; G194-L196 PolarHBondContact O-N 2.87Å; G194-L197 PolarHBondContact O-N 3.49Å; G194-A198 PolarHBondContact O-N 3.21Å
195I84.9Confident83.8Confident72 Ų7259 Ų5937%0.36931%0.308SS..Hα-helixtrans-60-45.6174.9-67.8166000110.3L191 Y192 L197 A198 M199L191-I195 HydrophobicContact CG-CD1 4.36Å; L191-I195 WeakPolarHBondContact O-CG1 3.2Å; L191-I195 PolarHBondContact O-N 3.04Å; Y192-I195 PolarHBondContact O-N 3.09Å; I195-L197 PolarHBondContact O-N 2.92Å; I195-A198 WeakPolarHBondContact O-CB 3.21Å; I195-A198 PolarHBondContact O-N 3.45Å; I195-M199 HydrophobicContact CG2-CG 4.48Å; I195-M199 VanDerWaalsContact O-CG 3.3Å; I195-M199 WeakPolarHBondContact O-CG 3.41Å; I195-M199 PolarHBondContact O-N 3.26Å
196L85.6Confident84.1Confident5 Ų561.7 Ų61.73%0.02632%0.321CS..Hα-helixtrans-58.5-47.8177.5-107.4140.6000112.9H29 Q33 I180 Y192 L193 G194 A198 M199 T200H29-L196 WeakPolarHBondContact CD2-CD2 3.07Å; Q33-L196 HydrophobicContact CB-CD2 4.3Å; Q33-L196 HydrophobicContact CG-CD2 4.33Å; I180-L196 HydrophobicContact CD1-CD1 3.1Å; Y192-L196 PolarHBondContact O-N 3.49Å; Y192-L196 VanDerWaalsContact O-N 3.11Å; L193-L196 WeakPolarHBondContact O-CB 3.37Å; L193-L196 PolarHBondContact O-N 3.02Å; G194-L196 VanDerWaalsContact C-N 3.34Å; G194-L196 PolarHBondContact O-N 2.87Å; L196-A198 VanDerWaalsContact C-N 3.32Å; L196-A198 PolarHBondContact O-N 3.49Å; L196-M199 PolarHBondContact O-N 3.32Å; L196-T200 WeakPolarHBondContact O-CG2 3.46Å; L196-T200 PolarHBondContact O-N 3.11Å
197L79.2Confident85Confident93 Ų9351 Ų5149%0.48728%0.28SS..Hα-helixtrans-63.3-37.7177.7-69170.8000111.8L193 G194 I195 M199 T200L193-L197 WeakPolarHBondContact O-CG 3.31Å; L193-L197 PolarHBondContact O-N 3.35Å; G194-L197 PolarHBondContact O-N 3.49Å; I195-L197 PolarHBondContact O-N 2.92Å; L197-M199 PolarHBondContact O-N 2.97Å; L197-T200 PolarHBondContact O-N 3.02Å; L197-T200 PolarHBondContact O-OG1 3.32Å
198A79.6Confident85.8Confident47 Ų4740.8 Ų40.839%0.38824%0.242SC..Hα-helixtrans-61.1-45173.600000111.7G194 I195 L196 T200 S201 I202G194-A198 PolarHBondContact O-N 3.21Å; I195-A198 WeakPolarHBondContact O-CB 3.21Å; I195-A198 PolarHBondContact O-N 3.45Å; L196-A198 VanDerWaalsContact C-N 3.32Å; L196-A198 PolarHBondContact O-N 3.49Å; A198-T200 PolarHBondContact O-N 2.98Å; A198-S201 PolarHBondContact O-N 2.69Å; A198-I202 PolarHBondContact O-N 3.08Å
199M86.1Confident86.5Confident36 Ų3640.8 Ų40.818%0.17724%0.243CC..Hα-helixtrans-63.6-29.3178-64.7-63.6-8100112.6L34 I195 L196 L197 S201 I202 G203L34-M199 HydrophobicContact CB-CE 3.98Å; L34-M199 HydrophobicContact CD1-CE 3.26Å; L34-M199 HydrophobicContact CD1-SD 4.25Å; L34-M199 HydrophobicContact CG-CE 4.26Å; I195-M199 HydrophobicContact CG2-CG 4.48Å; I195-M199 VanDerWaalsContact O-CG 3.3Å; I195-M199 WeakPolarHBondContact O-CG 3.41Å; I195-M199 PolarHBondContact O-N 3.26Å; L196-M199 PolarHBondContact O-N 3.32Å; L197-M199 PolarHBondContact O-N 2.97Å; M199-S201 PolarHBondContact O-N 3.31Å; M199-I202 PolarHBondContact O-N 3.2Å; M199-I202 HydrophobicContact SD-CD1 3.96Å; M199-G203 PolarHBondContact O-N 3.09Å; M199-G203 VanDerWaalsContact O-N 3.12Å
200T84.1Confident87.2Confident29 Ų2942.1 Ų42.118%0.17825%0.252CS..Hα-helixtrans-63.9-2617366.40000113.9Q33 L37 L196 L197 A198 P204Q33-T200 HydrophobicContact CG-CG2 3.62Å; L37-T200 HydrophobicContact CD1-CG2 3.85Å; L37-T200 WeakPolarHBondContact CD1-O 3Å; L196-T200 WeakPolarHBondContact O-CG2 3.46Å; L196-T200 PolarHBondContact O-N 3.11Å; L197-T200 PolarHBondContact O-N 3.02Å; L197-T200 PolarHBondContact O-OG1 3.32Å; A198-T200 PolarHBondContact O-N 2.98Å; T200-P204 WeakPolarHBondContact O-CD 3.48Å
201S81.3Confident88Confident48 Ų4838.1 Ų38.134%0.33623%0.226SC..Hα-helixtrans-87.6-30.9177.8-56.30000112.3A198 M199A198-S201 PolarHBondContact O-N 2.69Å; M199-S201 PolarHBondContact O-N 3.31Å
202I89.1Confident88.6Confident70 Ų7033.1 Ų33.136%0.35920%0.199SC..Hα-helixtrans-72.4-37.4179.6-65.9168.9000111.6L34 A198 M199 A205 L206L34-I202 HydrophobicContact CD1-CG2 3.98Å; A198-I202 PolarHBondContact O-N 3.08Å; M199-I202 PolarHBondContact O-N 3.2Å; M199-I202 HydrophobicContact SD-CD1 3.96Å; I202-A205 WeakPolarHBondContact O-CB 3.5Å; I202-A205 PolarHBondContact O-N 3.38Å; I202-A205 VanDerWaalsContact O-N 3.16Å; I202-L206 HydrophobicContact CG2-CD1 3.77Å; I202-L206 HydrophobicContact CG2-CG 4.03Å; I202-L206 PolarHBondContact O-N 3.4Å
203G92.1Very high89.1Confident0 Ų037.7 Ų37.70%022%0.22CC..Hα-helixtrans-51.4-56.2-179.100000113.9L38 M199 A205 L206 G207L38-G203 WeakPolarHBondContact CA-O 3.28Å; M199-G203 PolarHBondContact O-N 3.09Å; M199-G203 VanDerWaalsContact O-N 3.12Å; G203-A205 VanDerWaalsContact C-N 3.32Å; G203-A205 PolarHBondContact O-N 3.15Å; G203-L206 PolarHBondContact O-N 3.39Å; G203-G207 PolarHBondContact O-N 3.32Å
204P92.1Very high89.8Confident29 Ų2936.4 Ų36.419%0.18821%0.213CC..Hα-helixtrans-60.8-38.1177.7-25.536.2000113.4L37 T200 G207 F208L37-P204 HydrophobicContact CB-CG 4.21Å; T200-P204 WeakPolarHBondContact O-CD 3.48Å; P204-G207 PolarHBondContact O-N 3Å; P204-G207 VanDerWaalsContact O-N 3.14Å; P204-F208 VanDerWaalsContact O-CD2 3.28Å; P204-F208 WeakPolarHBondContact O-CD2 3.5Å; P204-F208 PolarHBondContact O-N 3.43Å
205A92.5Very high90.7Very high15 Ų1534.7 Ų34.712%0.12420%0.195CC..Hα-helixtrans-60-47.3177.400000111.4I202 G203 G207 F208 V209 M361I202-A205 WeakPolarHBondContact O-CB 3.5Å; I202-A205 PolarHBondContact O-N 3.38Å; I202-A205 VanDerWaalsContact O-N 3.16Å; G203-A205 VanDerWaalsContact C-N 3.32Å; G203-A205 PolarHBondContact O-N 3.15Å; A205-G207 VanDerWaalsContact C-N 3.31Å; A205-G207 PolarHBondContact O-N 3.38Å; A205-F208 PolarHBondContact O-N 3.03Å; A205-V209 WeakPolarHBondContact O-CG2 3.3Å; A205-V209 PolarHBondContact O-N 2.96Å; A205-M361 HydrophobicContact CB-CB 3.6Å; A205-M361 HydrophobicContact CB-CG 4.01Å
206L94.9Very high91.1Very high67 Ų6737.1 Ų37.135%0.35120%0.2SC..Hα-helixtrans-62.5-38173.8-69.3176.1000111.7L34 L38 I202 G203 F208 V209 T210L34-L206 HydrophobicContact CD1-CD1 3.81Å; L34-L206 HydrophobicContact CD2-CD1 3.89Å; L34-L206 HydrophobicContact CG-CD1 4.12Å; L38-L206 HydrophobicContact CD1-CB 4.05Å; I202-L206 HydrophobicContact CG2-CD1 3.77Å; I202-L206 HydrophobicContact CG2-CG 4.03Å; I202-L206 PolarHBondContact O-N 3.4Å; G203-L206 PolarHBondContact O-N 3.39Å; L206-F208 VanDerWaalsContact C-N 3.33Å; L206-F208 PolarHBondContact O-N 3.32Å; L206-V209 PolarHBondContact O-N 3.38Å; L206-T210 WeakPolarHBondContact O-CB 3.39Å; L206-T210 PolarHBondContact O-N 2.93Å; L206-T210 PolarHBondContact O-OG1 3Å
207G96.3Very high91.4Very high0 Ų041 Ų410%022%0.216CC..Hα-helixtrans-58.3-40.817400000113.7G203 P204 A205 G211G203-G207 PolarHBondContact O-N 3.32Å; P204-G207 PolarHBondContact O-N 3Å; P204-G207 VanDerWaalsContact O-N 3.14Å; A205-G207 VanDerWaalsContact C-N 3.31Å; A205-G207 PolarHBondContact O-N 3.38Å; G207-G211 PolarHBondContact O-N 3.19Å
208F96.2Very high92.1Very high1 Ų137 Ų370%0.00420%0.195CC..Hα-helixtrans-68.7-41.1173.4-82.8-76.1000112.8K44 P204 A205 L206 G211 S212 A334 P338 I356 M361K44-F208 HydrophobicContact CB-CE1 4.41Å; K44-F208 HydrophobicContact CB-CZ 3.8Å; P204-F208 VanDerWaalsContact O-CD2 3.28Å; P204-F208 WeakPolarHBondContact O-CD2 3.5Å; P204-F208 PolarHBondContact O-N 3.43Å; A205-F208 PolarHBondContact O-N 3.03Å; L206-F208 VanDerWaalsContact C-N 3.33Å; L206-F208 PolarHBondContact O-N 3.32Å; F208-G211 CarbonylContact O-C 3.48Å; F208-G211 WeakPolarHBondContact O-CA 3.4Å; F208-G211 PolarHBondContact O-N 3.29Å; F208-S212 PolarHBondContact O-N 3.36Å; F208-A334 VanDerWaalsContact CZ-O 3.23Å; F208-A334 WeakPolarHBondContact CZ-O 3.07Å; F208-P338 HydrophobicContact CD1-CG 4.35Å; F208-P338 HydrophobicContact CE1-CG 3.68Å; F208-I356 HydrophobicContact CD1-CB 4.16Å; F208-I356 HydrophobicContact CD1-CG2 4.14Å; F208-I356 HydrophobicContact CD2-CG2 4.17Å; F208-I356 HydrophobicContact CE1-CB 4.47Å; F208-I356 HydrophobicContact CE1-CG2 4.16Å; F208-I356 HydrophobicContact CE2-CG2 4.18Å; F208-I356 HydrophobicContact CG-CB 4.41Å; F208-I356 HydrophobicContact CG-CG2 4.17Å; F208-I356 HydrophobicContact CZ-CG2 4.19Å; F208-M361 HydrophobicContact CD2-CE 4.09Å; F208-M361 HydrophobicContact CE2-CE 3.84Å
209V96.3Very high92.7Very high49 Ų4934.7 Ų34.730%0.29718%0.176SC..Hα-helixtrans-66.4-44.3178.1172.90000111.3A205 L206 G211 S212 F213 M354A205-V209 WeakPolarHBondContact O-CG2 3.3Å; A205-V209 PolarHBondContact O-N 2.96Å; L206-V209 PolarHBondContact O-N 3.38Å; V209-G211 VanDerWaalsContact C-N 3.3Å; V209-G211 PolarHBondContact O-N 3.36Å; V209-S212 VanDerWaalsContact O-CB 3.3Å; V209-S212 WeakPolarHBondContact O-CB 3.4Å; V209-S212 PolarHBondContact O-N 3.03Å; V209-S212 VanDerWaalsContact O-N 3.12Å; V209-F213 PolarHBondContact O-N 3.26Å; V209-M354 HydrophobicContact CG1-CE 4.31Å; V209-M354 HydrophobicContact CG2-SD 4.4Å
210T96Very high92.9Very high37 Ų3733 Ų3323%0.22717%0.168CC..Hα-helixtrans-60.6-41.5172.2-59.30000110.8Y42 L206 S212 F213 L214Y42-T210 HydrophobicContact CD2-CG2 4.32Å; L206-T210 WeakPolarHBondContact O-CB 3.39Å; L206-T210 PolarHBondContact O-N 2.93Å; L206-T210 PolarHBondContact O-OG1 3Å; T210-S212 PolarHBondContact O-N 2.86Å; T210-F213 PolarHBondContact O-N 3Å; T210-L214 HydrophobicContact CG2-CD1 3.66Å; T210-L214 HydrophobicContact CG2-CG 4.18Å; T210-L214 WeakPolarHBondContact O-CG 3.34Å; T210-L214 PolarHBondContact O-N 2.85Å
211G95.7Very high93.2Very high0 Ų035.5 Ų35.50%018%0.176CC..Hα-helixtrans-55.4-47.8169.900000112.6S45 G207 F208 V209 F213 L214 M215S45-G211 WeakPolarHBondContact OG-CA 3.41Å; G207-G211 PolarHBondContact O-N 3.19Å; F208-G211 CarbonylContact O-C 3.48Å; F208-G211 WeakPolarHBondContact O-CA 3.4Å; F208-G211 PolarHBondContact O-N 3.29Å; V209-G211 VanDerWaalsContact C-N 3.3Å; V209-G211 PolarHBondContact O-N 3.36Å; G211-F213 VanDerWaalsContact C-N 3.29Å; G211-F213 PolarHBondContact O-N 3.16Å; G211-L214 PolarHBondContact O-N 2.98Å; G211-M215 VanDerWaalsContact O-CB 3.31Å; G211-M215 WeakPolarHBondContact O-CB 3.47Å; G211-M215 WeakPolarHBondContact O-CG 3.47Å; G211-M215 PolarHBondContact O-N 3.49Å
212S96.3Very high93.5Very high1 Ų136.6 Ų36.61%0.00718%0.179CC..Hα-helixtrans-56.1-43.8177.1-179.40000112.4F208 V209 T210 P350F208-S212 PolarHBondContact O-N 3.36Å; V209-S212 VanDerWaalsContact O-CB 3.3Å; V209-S212 WeakPolarHBondContact O-CB 3.4Å; V209-S212 PolarHBondContact O-N 3.03Å; V209-S212 VanDerWaalsContact O-N 3.12Å; T210-S212 PolarHBondContact O-N 2.86Å; S212-P350 VanDerWaalsContact CB-O 3.26Å; S212-P350 WeakPolarHBondContact CB-O 3.42Å; S212-P350 VanDerWaalsContact O-CB 3.29Å; S212-P350 WeakPolarHBondContact O-CB 3.46Å; S212-P350 PolarHBondContact OG-O 3.5Å
213F96.3Very high93.4Very high116 Ų11637 Ų3751%0.50918%0.178SC..Hα-helixtrans-70.4-49.7-180-177-103000112.4V209 T210 G211 M215 R216 F217V209-F213 PolarHBondContact O-N 3.26Å; T210-F213 PolarHBondContact O-N 3Å; G211-F213 VanDerWaalsContact C-N 3.29Å; G211-F213 PolarHBondContact O-N 3.16Å; F213-M215 PolarHBondContact O-N 3.19Å; F213-R216 VanDerWaalsContact O-CB 3.32Å; F213-R216 WeakPolarHBondContact O-CB 3.5Å; F213-R216 WeakPolarHBondContact O-CG 3.47Å; F213-R216 PolarHBondContact O-N 2.81Å; F213-F217 HydrophobicContact CD1-CE2 4.45Å; F213-F217 AromaticContact CE1-CE2 3.96Å; F213-F217 HydrophobicContact CE1-CE2 3.96Å; F213-F217 HydrophobicContact CZ-CE2 4.24Å; F213-F217 HydrophobicContact CZ-CZ 4.41Å
214L95.8Very high93Very high13 Ų1338.3 Ų38.37%0.06819%0.185CC..Hα-helixtrans-73.8-27-172.5-61.3179.7000113.4Y42 T210 G211 R216 F217 L244Y42-L214 HydrophobicContact CE2-CD1 4.08Å; T210-L214 HydrophobicContact CG2-CD1 3.66Å; T210-L214 HydrophobicContact CG2-CG 4.18Å; T210-L214 WeakPolarHBondContact O-CG 3.34Å; T210-L214 PolarHBondContact O-N 2.85Å; G211-L214 PolarHBondContact O-N 2.98Å; L214-R216 PolarHBondContact O-N 3.21Å; L214-F217 PolarHBondContact O-N 3.2Å; L214-L244 HydrophobicContact CD1-CG 4.43Å; L214-L244 HydrophobicContact CD2-CD2 3.85Å; L214-L244 HydrophobicContact CD2-CG 4.18Å
215M94.1Very high92.4Very high0 Ų040.4 Ų40.40%020%0.198CC..THydrogen-bonded Turntrans-71.5-5.9176.2-63.6-62.7160.400113.8Y42 S46 T49 G211 F213 F217 W238 W242 I349 P350Y42-M215 HydrophobicContact CE2-CE 4.29Å; S46-M215 WeakPolarHBondContact OG-CE 3.4Å; T49-M215 HydrophobicContact CG2-SD 4.13Å; G211-M215 VanDerWaalsContact O-CB 3.31Å; G211-M215 WeakPolarHBondContact O-CB 3.47Å; G211-M215 WeakPolarHBondContact O-CG 3.47Å; G211-M215 PolarHBondContact O-N 3.49Å; F213-M215 PolarHBondContact O-N 3.19Å; M215-F217 VanDerWaalsContact C-N 3.3Å; M215-W238 PolarHBondContact O-NE1 3.04Å; M215-W242 HydrophobicContact CE-CB 3.67Å; M215-W242 HydrophobicContact SD-CB 4.17Å; M215-I349 HydrophobicContact CB-CG2 4.01Å; M215-I349 HydrophobicContact CG-CG2 4Å; M215-P350 HydrophobicContact CB-CG 4.15Å
216R93.6Very high91.5Very high124 Ų12450.9 Ų50.947%0.46823%0.234SC..THydrogen-bonded Turntrans-73.5-22.4172.8-65.5178.4-178.3-165.1-1.7113.1F213 L214 Q233 W238 P350F213-R216 VanDerWaalsContact O-CB 3.32Å; F213-R216 WeakPolarHBondContact O-CB 3.5Å; F213-R216 WeakPolarHBondContact O-CG 3.47Å; F213-R216 PolarHBondContact O-N 2.81Å; L214-R216 PolarHBondContact O-N 3.21Å; R216-Q233 PolarHBondContact O-NE2 3.37Å; R216-W238 VanDerWaalsContact O-CZ2 3.27Å; R216-W238 WeakPolarHBondContact O-CZ2 3.42Å; R216-P350 HydrophobicContact CG-CB 3.97Å; R216-P350 HydrophobicContact CG-CG 3.75Å
217F92.7Very high90.2Very high86 Ų8651.2 Ų51.238%0.37725%0.254SS..SBendtrans-87.5137.4176.4-59.9-78.4000109.5F213 L214 M215 F221 G240 A241F213-F217 HydrophobicContact CD1-CE2 4.45Å; F213-F217 AromaticContact CE1-CE2 3.96Å; F213-F217 HydrophobicContact CE1-CE2 3.96Å; F213-F217 HydrophobicContact CZ-CE2 4.24Å; F213-F217 HydrophobicContact CZ-CZ 4.41Å; L214-F217 PolarHBondContact O-N 3.2Å; M215-F217 VanDerWaalsContact C-N 3.3Å; F217-F221 HydrophobicContact CB-CD1 4.02Å; F217-F221 HydrophobicContact CB-CE1 4.27Å; F217-G240 CarbonylContact O-C 3.27Å; F217-G240 VanDerWaalsContact O-CA 3.28Å; F217-G240 WeakPolarHBondContact O-CA 3.36Å; F217-A241 HydrophobicContact CB-CB 3.95Å; F217-A241 PolarHBondContact O-N 3.01Å
218Y92.7Very high89Confident8 Ų856 Ų563%0.03128%0.277CS..BIsolated β-bridgetrans-67.1141.4177.2-178.9-107.2000110.7Y116 D220 F221 L224 I229 L231 W238Y116-Y218 WeakPolarHBondContact CD1-OH 3.44Å; Y218-D220 VanDerWaalsContact C-N 3.29Å; Y218-D220 HydrophobicContact CE1-CB 4.23Å; Y218-D220 PolarHBondContact O-N 3.01Å; Y218-D220 VanDerWaalsContact O-N 3.1Å; Y218-F221 WeakPolarHBondContact O-CB 3.46Å; Y218-F221 WeakPolarHBondContact O-CD1 3.47Å; Y218-F221 PolarHBondContact O-N 3.42Å; Y218-F221 VanDerWaalsContact O-N 3.12Å; Y218-L224 HydrophobicContact CE1-CD1 4.28Å; Y218-I229 HydrophobicContact CD1-CD1 4.08Å; Y218-I229 HydrophobicContact CD1-CG1 4.23Å; Y218-I229 HydrophobicContact CD1-CG2 4.11Å; Y218-I229 HydrophobicContact CD2-CG2 4.27Å; Y218-I229 HydrophobicContact CG-CD1 4.48Å; Y218-I229 HydrophobicContact CG-CG2 3.86Å; Y218-L231 HydrophobicContact CE2-CD1 3.79Å; Y218-W238 HydrophobicContact CD2-CD2 4.38Å; Y218-W238 AromaticContact CD2-CE3 3.93Å; Y218-W238 HydrophobicContact CD2-CE3 3.93Å; Y218-W238 HydrophobicContact CD2-CH2 4.24Å; Y218-W238 AromaticContact CD2-CZ3 3.85Å; Y218-W238 HydrophobicContact CD2-CZ3 3.85Å; Y218-W238 HydrophobicContact CG-CH2 4.43Å; Y218-W238 HydrophobicContact CG-CZ3 4.36Å
219V92.3Very high88.1Confident0 Ų057.8 Ų57.80%029%0.286CS..THydrogen-bonded Turntrans-58.2-33.3-165.971.30000116.1R53 H110 Y116 V239 G240 W243R53-V219 VanDerWaalsContact NH1-CG1 3.28Å; H110-V219 PolarHBondContact CE1-O 2.86Å; Y116-V219 HydrophobicContact CD1-CG1 4.49Å; Y116-V219 HydrophobicContact CG-CG1 4.41Å; V219-V239 HydrophobicContact CB-CB 4.04Å; V219-V239 HydrophobicContact CB-CG1 3.65Å; V219-V239 WeakPolarHBondContact CB-O 3.42Å; V219-V239 HydrophobicContact CG1-CB 3.83Å; V219-V239 HydrophobicContact CG1-CG1 3.75Å; V219-V239 HydrophobicContact CG2-CG1 3.85Å; V219-V239 PolarHBondContact N-O 3.35Å; V219-G240 WeakPolarHBondContact CB-O 3.47Å; V219-G240 VanDerWaalsContact CG2-O 3.32Å; V219-G240 WeakPolarHBondContact CG2-O 3.46Å; V219-W243 PolarHBondContact O-NE1 3.48Å
220D90.9Very high87Confident0 Ų059.5 Ų59.50%029%0.29CS..THydrogen-bonded Turntrans-112.234.4-179.3-57.7-48.9000112R53 H110 Y116 Y218 D222 K223 L224R53-D220 IonicContact CZ-OD1 3.46Å; R53-D220 IonicContact NH1-OD1 3.76Å; R53-D220 PolarHBondContact NH1-OD1 3.18Å; R53-D220 IonicContact NH1-OD2 2.64Å; R53-D220 IonicContact NH2-OD1 2.61Å; R53-D220 PolarHBondContact NH2-OD1 3.34Å; R53-D220 VanDerWaalsContact NH2-OD1 3.13Å; H110-D220 IonicContact CE1-OD1 3.56Å; H110-D220 PolarHBondContact CE1-OD1 3.48Å; H110-D220 IonicContact ND1-OD1 3.74Å; Y116-D220 WeakPolarHBondContact CA-OD2 3.38Å; Y116-D220 WeakPolarHBondContact CB-OD2 3.09Å; Y116-D220 PolarHBondContact N-OD2 2.81Å; Y218-D220 VanDerWaalsContact C-N 3.29Å; Y218-D220 HydrophobicContact CE1-CB 4.23Å; Y218-D220 PolarHBondContact O-N 3.01Å; Y218-D220 VanDerWaalsContact O-N 3.1Å; D220-D222 WeakPolarHBondContact CA-OD1 3.47Å; D220-D222 PolarHBondContact O-N 2.84Å; D220-D222 VanDerWaalsContact O-N 3.12Å; D220-K223 HydrophobicContact CB-CB 4.19Å; D220-K223 HydrophobicContact CB-CD 4.24Å; D220-K223 HydrophobicContact CB-CG 4.34Å; D220-K223 PolarHBondContact O-N 3.31Å; D220-K223 IonicContact OD1-NZ 2.88Å; D220-L224 PolarHBondContact O-N 3.29Å
221F89.9Confident86.3Confident82 Ų8258.3 Ų58.336%0.3628%0.283SS..THydrogen-bonded Turntrans-59.5-17.9173.678.6-95.1000113.3F217 Y218 A241 W243 L244F217-F221 HydrophobicContact CB-CD1 4.02Å; F217-F221 HydrophobicContact CB-CE1 4.27Å; Y218-F221 WeakPolarHBondContact O-CB 3.46Å; Y218-F221 WeakPolarHBondContact O-CD1 3.47Å; Y218-F221 PolarHBondContact O-N 3.42Å; Y218-F221 VanDerWaalsContact O-N 3.12Å; F221-A241 HydrophobicContact CD1-CB 4.12Å; F221-A241 HydrophobicContact CE1-CB 3.86Å; F221-W243 HydrophobicContact CE1-CH2 4.36Å; F221-W243 AromaticContact CE1-CZ2 3.78Å; F221-W243 HydrophobicContact CE1-CZ2 3.78Å; F221-W243 HydrophobicContact CZ-CH2 4.2Å; F221-W243 HydrophobicContact CZ-CZ2 4.05Å; F221-L244 HydrophobicContact CE1-CD2 4.28Å; F221-L244 HydrophobicContact CZ-CD2 4.22Å
222D88.6Confident85.7Confident71 Ų7164.7 Ų64.738%0.3831%0.312SS..THydrogen-bonded Turntrans-83.5-20.3175.164.7-57.3000113.1H110 D220 W243H110-D222 IonicContact CE1-OD1 2.82Å; H110-D222 IonicContact NE2-OD1 3.13Å; H110-D222 PolarHBondContact NE2-OD1 3.2Å; H110-D222 IonicContact NE2-OD2 3.5Å; H110-D222 PolarHBondContact NE2-OD2 3.47Å; D220-D222 WeakPolarHBondContact CA-OD1 3.47Å; D220-D222 PolarHBondContact O-N 2.84Å; D220-D222 VanDerWaalsContact O-N 3.12Å; D222-W243 HydrophobicContact CB-CZ2 4.33Å
223K85.8Confident85.1Confident78 Ų7868 Ų6834%0.33933%0.328SS..THydrogen-bonded Turntrans-105.2-25.5-177.4-52.4179.4-175.5171.40113H110 S113 D220H110-K223 PolarHBondContact O-NZ 2.99Å; S113-K223 PolarHBondContact O-NZ 3.04Å; D220-K223 HydrophobicContact CB-CB 4.19Å; D220-K223 HydrophobicContact CB-CD 4.24Å; D220-K223 HydrophobicContact CB-CG 4.34Å; D220-K223 PolarHBondContact O-N 3.31Å; D220-K223 IonicContact OD1-NZ 2.88Å
224L83.3Confident84.5Confident28 Ų2868.7 Ų68.715%0.14733%0.331CS..SBendtrans-118.3140.8-175.6-63.6171.5000111.9M121 Y218 D220 I229M121-L224 HydrophobicContact CE-CD1 4.01Å; Y218-L224 HydrophobicContact CE1-CD1 4.28Å; D220-L224 PolarHBondContact O-N 3.29Å; L224-I229 HydrophobicContact CB-CG1 4.5Å
225P80.7Confident84Confident72 Ų7269.2 Ų69.247%0.46833%0.334SS..  trans-68.2150.8171.329.8-33.3000111G227 E228P225-G227 PolarHBondContact O-N 3.46Å; P225-E228 HydrophobicContact CG-CB 4.31Å; P225-E228 VanDerWaalsContact CG-CD 3.41Å; P225-E228 HydrophobicContact CG-CG 3.85Å; P225-E228 WeakPolarHBondContact CG-OE1 3.48Å; P225-E228 PolarHBondContact O-N 3.08Å
226R73.2Confident83.5Confident235 Ų23571 Ų7189%0.88734%0.343SS*.G310 helixtrans-56.4-29.5-174.5-67.9-175.9-175.9178.92.4114.4E228 I229R226-E228 VanDerWaalsContact C-N 3.28Å; R226-E228 PolarHBondContact O-N 3.48Å; R226-I229 PolarHBondContact O-N 3.49Å
227G67.5Low83.3Confident75 Ų7566 Ų6677%0.77332%0.324SS*.G310 helixtrans-70.2-21179.600000114.3P225P225-G227 PolarHBondContact O-N 3.46Å
228E71.9Confident83.2Confident101 Ų10162.7 Ų62.747%0.47231%0.309SS..G310 helixtrans-90.4-6.6178.7-69173.8-152.900112.5P225 R226 E230P225-E228 HydrophobicContact CG-CB 4.31Å; P225-E228 VanDerWaalsContact CG-CD 3.41Å; P225-E228 HydrophobicContact CG-CG 3.85Å; P225-E228 WeakPolarHBondContact CG-OE1 3.48Å; P225-E228 PolarHBondContact O-N 3.08Å; R226-E228 VanDerWaalsContact C-N 3.28Å; R226-E228 PolarHBondContact O-N 3.48Å; E228-E230 PolarHBondContact O-N 2.9Å
229I77.4Confident83.2Confident37 Ų3762.3 Ų62.319%0.1931%0.308CS..  trans-88.589179.2-53.9174.4000108.7Y218 L224 R226 L231Y218-I229 HydrophobicContact CD1-CD1 4.08Å; Y218-I229 HydrophobicContact CD1-CG1 4.23Å; Y218-I229 HydrophobicContact CD1-CG2 4.11Å; Y218-I229 HydrophobicContact CD2-CG2 4.27Å; Y218-I229 HydrophobicContact CG-CD1 4.48Å; Y218-I229 HydrophobicContact CG-CG2 3.86Å; L224-I229 HydrophobicContact CB-CG1 4.5Å; R226-I229 PolarHBondContact O-N 3.49Å; I229-L231 VanDerWaalsContact C-N 3.34Å
230E72.5Confident83.2Confident85 Ų8562.3 Ų62.340%0.39731%0.308SS..  trans-84.4-6.9-177.5-64-178.617600114E228E228-E230 PolarHBondContact O-N 2.9Å
231L80.9Confident83.4Confident13 Ų1362.3 Ų62.37%0.06831%0.308CS..  trans-88139.3-174-64.9172.5000112.8Y118 Y218 I229 D235 R237 W238Y118-L231 HydrophobicContact CD1-CD1 4Å; Y118-L231 HydrophobicContact CD2-CD1 4.35Å; Y118-L231 HydrophobicContact CD2-CD2 4.46Å; Y118-L231 HydrophobicContact CE1-CD1 3.7Å; Y118-L231 HydrophobicContact CE1-CG 4.32Å; Y118-L231 HydrophobicContact CE2-CD1 4.07Å; Y118-L231 HydrophobicContact CE2-CD2 3.98Å; Y118-L231 HydrophobicContact CE2-CG 4.11Å; Y118-L231 HydrophobicContact CG-CD1 4.32Å; Y218-L231 HydrophobicContact CE2-CD1 3.79Å; I229-L231 VanDerWaalsContact C-N 3.34Å; L231-D235 HydrophobicContact CD2-CB 4.34Å; L231-D235 WeakPolarHBondContact CD2-OD2 3.09Å; L231-R237 HydrophobicContact CD1-CB 4.33Å; L231-R237 HydrophobicContact CD2-CB 4.26Å; L231-W238 HydrophobicContact CB-CE3 4.05Å; L231-W238 VanDerWaalsContact O-CZ3 3.27Å; L231-W238 WeakPolarHBondContact O-CZ3 3.21Å
232E82.6Confident83.7Confident133 Ų13358.4 Ų58.462%0.62129%0.291SS*.  trans-94.5157.6169.9-62.5-171.2170.900112K234 D235E232-K234 PolarHBondContact O-N 3.44Å; E232-K234 VanDerWaalsContact O-N 3.09Å; E232-D235 VanDerWaalsContact O-CB 3.26Å; E232-D235 WeakPolarHBondContact O-CB 3.41Å; E232-D235 PolarHBondContact O-N 3.1Å
233Q84.2Confident84Confident71 Ų7155.8 Ų55.833%0.33228%0.275SS..THydrogen-bonded Turntrans-61.3-21.7-179.2-68.7179.64.500114.5R216 W238 T348R216-Q233 PolarHBondContact O-NE2 3.37Å; Q233-W238 HydrophobicContact CG-CD2 4.35Å; Q233-W238 HydrophobicContact CG-CH2 4.12Å; Q233-W238 HydrophobicContact CG-CZ2 3.84Å; Q233-W238 HydrophobicContact CG-CZ3 4.49Å; Q233-T348 HydrophobicContact CB-CG2 4.33Å
234K84.4Confident84.5Confident130 Ų13053.9 Ų53.957%0.56527%0.269SS*.THydrogen-bonded Turntrans-84.5-15.4178.6-163.8178.1177.2-170.90112.3E232 T348E232-K234 PolarHBondContact O-N 3.44Å; E232-K234 VanDerWaalsContact O-N 3.09Å; K234-T348 HydrophobicContact CB-CG2 4.47Å
235D84.6Confident85.1Confident25 Ų2552.6 Ų52.613%0.13426%0.262CS..SBendtrans-64.4136.9179.5-165.3-49.6000110.6L231 E232 R237 W238L231-D235 HydrophobicContact CD2-CB 4.34Å; L231-D235 WeakPolarHBondContact CD2-OD2 3.09Å; E232-D235 VanDerWaalsContact O-CB 3.26Å; E232-D235 WeakPolarHBondContact O-CB 3.41Å; E232-D235 PolarHBondContact O-N 3.1Å; D235-R237 PolarHBondContact O-N 3.31Å; D235-R237 VanDerWaalsContact OD1-CB 3.26Å; D235-R237 WeakPolarHBondContact OD1-CB 3.47Å; D235-R237 WeakPolarHBondContact OD1-CG 3.14Å; D235-R237 PolarHBondContact OD1-N 2.87Å; D235-R237 IonicContact OD1-NE 3.34Å; D235-R237 PolarHBondContact OD1-NE 3.24Å; D235-R237 VanDerWaalsContact OD1-NE 3.11Å; D235-R237 IonicContact OD2-CZ 3.75Å; D235-R237 IonicContact OD2-NE 3.29Å; D235-R237 PolarHBondContact OD2-NE 3.38Å; D235-R237 IonicContact OD2-NH2 3.73Å; D235-R237 PolarHBondContact OD2-NH2 3.09Å; D235-W238 VanDerWaalsContact O-CB 3.26Å; D235-W238 WeakPolarHBondContact O-CB 3.25Å; D235-W238 PolarHBondContact O-N 2.98Å
236L85Confident85.9Confident37 Ų3749.2 Ų49.219%0.19424%0.24CC..THydrogen-bonded Turntrans-62.1-22.6177.6-67.8-177.5000112.6R52 F437 P439 T487 Y576R52-L236 PolarHBondContact NH1-O 3.41Å; R52-L236 VanDerWaalsContact NH1-O 3.17Å; L236-F437 HydrophobicContact CB-CE1 3.99Å; L236-F437 HydrophobicContact CB-CZ 4.26Å; L236-F437 HydrophobicContact CD1-CZ 3.97Å; L236-P439 HydrophobicContact CB-CG 4.41Å; L236-P439 HydrophobicContact CD1-CG 4.16Å; L236-P439 HydrophobicContact CG-CG 4.5Å; L236-T487 HydrophobicContact CD1-CG2 3.61Å; L236-T487 HydrophobicContact CG-CG2 3.82Å; L236-Y576 HydrophobicContact CD1-CE1 3.99Å
237R88.3Confident87Confident20 Ų2040.2 Ų40.28%0.07521%0.209CC..THydrogen-bonded Turntrans-83.5-10.8178.1-58.5172.6-68171.32.8113.1Y116 D120 L231 D235 V239 F437 N438Y116-R237 WeakPolarHBondContact CE1-O 3.41Å; Y116-R237 PolarHBondContact OH-O 2.96Å; Y116-R237 VanDerWaalsContact OH-O 3.11Å; D120-R237 IonicContact OD2-CZ 3.28Å; D120-R237 IonicContact OD2-NH1 3.82Å; D120-R237 PolarHBondContact OD2-NH1 3.45Å; D120-R237 IonicContact OD2-NH2 3.11Å; L231-R237 HydrophobicContact CD1-CB 4.33Å; L231-R237 HydrophobicContact CD2-CB 4.26Å; D235-R237 PolarHBondContact O-N 3.31Å; D235-R237 VanDerWaalsContact OD1-CB 3.26Å; D235-R237 WeakPolarHBondContact OD1-CB 3.47Å; D235-R237 WeakPolarHBondContact OD1-CG 3.14Å; D235-R237 PolarHBondContact OD1-N 2.87Å; D235-R237 IonicContact OD1-NE 3.34Å; D235-R237 PolarHBondContact OD1-NE 3.24Å; D235-R237 VanDerWaalsContact OD1-NE 3.11Å; D235-R237 IonicContact OD2-CZ 3.75Å; D235-R237 IonicContact OD2-NE 3.29Å; D235-R237 PolarHBondContact OD2-NE 3.38Å; D235-R237 IonicContact OD2-NH2 3.73Å; D235-R237 PolarHBondContact OD2-NH2 3.09Å; R237-V239 PolarHBondContact O-N 3.47Å; R237-F437 WeakPolarHBondContact CD-O 3.3Å; R237-F437 HydrophobicContact CG-CD1 4.02Å; R237-F437 HydrophobicContact CG-CE1 4.26Å; R237-N438 PolarHBondContact NH1-ND2 3.49Å; R237-N438 PolarHBondContact NH1-OD1 3.02Å; R237-N438 PolarHBondContact NH2-OD1 3.32Å; R237-N438 VanDerWaalsContact NH2-OD1 3.15Å
238W90.9Very high88.4Confident16 Ų1640.2 Ų40.26%0.06119%0.194CC..  trans-61.8133.1-179.7-179.5-90.2000112R52 M215 R216 Y218 L231 Q233 D235R52-W238 PolarHBondContact NH1-O 3.29Å; M215-W238 PolarHBondContact O-NE1 3.04Å; R216-W238 VanDerWaalsContact O-CZ2 3.27Å; R216-W238 WeakPolarHBondContact O-CZ2 3.42Å; Y218-W238 HydrophobicContact CD2-CD2 4.38Å; Y218-W238 AromaticContact CD2-CE3 3.93Å; Y218-W238 HydrophobicContact CD2-CE3 3.93Å; Y218-W238 HydrophobicContact CD2-CH2 4.24Å; Y218-W238 AromaticContact CD2-CZ3 3.85Å; Y218-W238 HydrophobicContact CD2-CZ3 3.85Å; Y218-W238 HydrophobicContact CG-CH2 4.43Å; Y218-W238 HydrophobicContact CG-CZ3 4.36Å; L231-W238 HydrophobicContact CB-CE3 4.05Å; L231-W238 VanDerWaalsContact O-CZ3 3.27Å; L231-W238 WeakPolarHBondContact O-CZ3 3.21Å; Q233-W238 HydrophobicContact CG-CD2 4.35Å; Q233-W238 HydrophobicContact CG-CH2 4.12Å; Q233-W238 HydrophobicContact CG-CZ2 3.84Å; Q233-W238 HydrophobicContact CG-CZ3 4.49Å; D235-W238 VanDerWaalsContact O-CB 3.26Å; D235-W238 WeakPolarHBondContact O-CB 3.25Å; D235-W238 PolarHBondContact O-N 2.98Å
239V92.3Very high89.5Confident0 Ų035.4 Ų35.40%017%0.172CC..  trans-125.8120.7173.5-179.60000106.9T49 R52 R53 Y116 V219 R237T49-V239 HydrophobicContact CG2-CB 4.25Å; T49-V239 HydrophobicContact CG2-CG1 3.33Å; R52-V239 HydrophobicContact CB-CG2 4.02Å; R53-V239 HydrophobicContact CB-CG1 3.95Å; Y116-V239 HydrophobicContact CD1-CG2 4.15Å; Y116-V239 HydrophobicContact CD2-CG2 4.42Å; Y116-V239 HydrophobicContact CE1-CB 4.38Å; Y116-V239 HydrophobicContact CE1-CG2 3.63Å; Y116-V239 HydrophobicContact CE2-CG2 3.93Å; Y116-V239 VanDerWaalsContact CZ-CG2 3.5Å; V219-V239 HydrophobicContact CB-CB 4.04Å; V219-V239 HydrophobicContact CB-CG1 3.65Å; V219-V239 WeakPolarHBondContact CB-O 3.42Å; V219-V239 HydrophobicContact CG1-CB 3.83Å; V219-V239 HydrophobicContact CG1-CG1 3.75Å; V219-V239 HydrophobicContact CG2-CG1 3.85Å; V219-V239 PolarHBondContact N-O 3.35Å; R237-V239 PolarHBondContact O-N 3.47Å
240G93.4Very high90.4Very high0 Ų033.8 Ų33.80%016%0.164CC..BIsolated β-bridgetrans-76.1162.317700000113.4T49 F217 V219 W242T49-G240 WeakPolarHBondContact CG2-O 3.33Å; F217-G240 CarbonylContact O-C 3.27Å; F217-G240 VanDerWaalsContact O-CA 3.28Å; F217-G240 WeakPolarHBondContact O-CA 3.36Å; V219-G240 WeakPolarHBondContact CB-O 3.47Å; V219-G240 VanDerWaalsContact CG2-O 3.32Å; V219-G240 WeakPolarHBondContact CG2-O 3.46Å; G240-W242 PolarHBondContact O-N 2.93Å
241A94.4Very high91.6Very high0 Ų033.1 Ų33.10%017%0.168CC..  trans-72.668.6177.600000112.9Y42 F217 F221 W243 L244Y42-A241 PolarHBondContact OH-O 2.95Å; F217-A241 HydrophobicContact CB-CB 3.95Å; F217-A241 PolarHBondContact O-N 3.01Å; F221-A241 HydrophobicContact CD1-CB 4.12Å; F221-A241 HydrophobicContact CE1-CB 3.86Å; A241-W243 VanDerWaalsContact C-N 3.29Å; A241-W243 PolarHBondContact O-N 3.09Å; A241-L244 HydrophobicContact CB-CB 4.37Å; A241-L244 PolarHBondContact O-N 3.25Å
242W95.4Very high92.3Very high0 Ų035.7 Ų35.70%018%0.179CC..Hα-helixtrans-67.2-22.7-176.366-91.4000114.6Y42 T49 I50 R53 Y54 M106 P109 H110 M215 G240 F246Y42-W242 WeakPolarHBondContact CE1-O 3.41Å; Y42-W242 VanDerWaalsContact OH-C 3.28Å; Y42-W242 WeakPolarHBondContact OH-CA 3.43Å; Y42-W242 PolarHBondContact OH-O 2.92Å; T49-W242 HydrophobicContact CG2-CB 3.98Å; T49-W242 HydrophobicContact CG2-CG 4.15Å; I50-W242 HydrophobicContact CD1-CD2 4.45Å; I50-W242 HydrophobicContact CD1-CE3 4.04Å; I50-W242 HydrophobicContact CG1-CB 4.39Å; I50-W242 HydrophobicContact CG1-CD2 3.87Å; I50-W242 HydrophobicContact CG1-CE3 3.96Å; I50-W242 HydrophobicContact CG1-CG 4.04Å; R53-W242 VanDerWaalsContact CD-NE1 3.33Å; Y54-W242 HydrophobicContact CE2-CH2 4.28Å; Y54-W242 AromaticContact CE2-CZ2 3.61Å; Y54-W242 HydrophobicContact CE2-CZ2 3.61Å; M106-W242 WeakPolarHBondContact O-CZ3 3.38Å; P109-W242 HydrophobicContact CB-CH2 4.01Å; P109-W242 HydrophobicContact CG-CH2 4.26Å; H110-W242 HydrophobicContact CB-CH2 4.27Å; H110-W242 HydrophobicContact CB-CZ2 3.85Å; M215-W242 HydrophobicContact CE-CB 3.67Å; M215-W242 HydrophobicContact SD-CB 4.17Å; G240-W242 PolarHBondContact O-N 2.93Å; W242-F246 HydrophobicContact CE3-CD2 4.07Å; W242-F246 AromaticContact CE3-CE2 3.82Å; W242-F246 HydrophobicContact CE3-CE2 3.82Å; W242-F246 HydrophobicContact CZ3-CD2 4.15Å; W242-F246 HydrophobicContact CZ3-CE2 4.05Å; W242-F246 VanDerWaalsContact O-CD2 3.31Å; W242-F246 WeakPolarHBondContact O-CD2 3.31Å
243W95.8Very high92.9Very high16 Ų1629.3 Ų29.36%0.06115%0.149CC..Hα-helixtrans-76.3-29179.257.5-92.4000111.8A107 H110 F111 V219 F221 D222 A241 G245 F246 L247A107-W243 HydrophobicContact CB-CB 4.42Å; H110-W243 HydrophobicContact CB-CB 3.67Å; H110-W243 HydrophobicContact CB-CG 3.71Å; H110-W243 AromaticContact CD2-CD1 3.53Å; H110-W243 AromaticContact CD2-CD2 3.67Å; H110-W243 AromaticContact CD2-CE2 3.57Å; H110-W243 AromaticContact CD2-CG 3.65Å; H110-W243 AromaticContact CD2-NE1 3.48Å; H110-W243 PolarHBondContact CD2-NE1 2.99Å; H110-W243 AromaticContact CE1-CD1 3.65Å; H110-W243 AromaticContact CE1-CE2 3.9Å; H110-W243 AromaticContact CE1-NE1 3.22Å; H110-W243 PolarHBondContact CE1-NE1 3.26Å; H110-W243 AromaticContact CG-CD1 3.19Å; H110-W243 AromaticContact CG-CG 3.51Å; H110-W243 AromaticContact CG-NE1 3.54Å; H110-W243 AromaticContact ND1-CD1 3.28Å; H110-W243 VanDerWaalsContact ND1-CD1 3.28Å; H110-W243 AromaticContact ND1-NE1 3.4Å; H110-W243 PolarHBondContact ND1-NE1 3.18Å; H110-W243 AromaticContact NE2-CD1 3.82Å; H110-W243 AromaticContact NE2-CE2 3.49Å; H110-W243 AromaticContact NE2-CZ2 3.85Å; H110-W243 AromaticContact NE2-NE1 3.3Å; H110-W243 PolarHBondContact NE2-NE1 3.45Å; F111-W243 HydrophobicContact CE1-CZ3 4.38Å; F111-W243 HydrophobicContact CE2-CE3 4.28Å; F111-W243 HydrophobicContact CZ-CD2 4.43Å; F111-W243 AromaticContact CZ-CE3 3.71Å; F111-W243 HydrophobicContact CZ-CE3 3.71Å; F111-W243 AromaticContact CZ-CZ3 3.79Å; F111-W243 HydrophobicContact CZ-CZ3 3.79Å; V219-W243 PolarHBondContact O-NE1 3.48Å; F221-W243 HydrophobicContact CE1-CH2 4.36Å; F221-W243 AromaticContact CE1-CZ2 3.78Å; F221-W243 HydrophobicContact CE1-CZ2 3.78Å; F221-W243 HydrophobicContact CZ-CH2 4.2Å; F221-W243 HydrophobicContact CZ-CZ2 4.05Å; D222-W243 HydrophobicContact CB-CZ2 4.33Å; A241-W243 VanDerWaalsContact C-N 3.29Å; A241-W243 PolarHBondContact O-N 3.09Å; W243-G245 PolarHBondContact O-N 2.89Å; W243-F246 WeakPolarHBondContact O-CB 3.37Å; W243-F246 PolarHBondContact O-N 3.47Å; W243-L247 HydrophobicContact CE3-CD1 3.64Å; W243-L247 HydrophobicContact CE3-CG 4.33Å; W243-L247 HydrophobicContact CZ3-CD1 3.51Å; W243-L247 PolarHBondContact O-N 3.39Å
244L95.8Very high93.6Very high38 Ų3830.5 Ų30.520%0.19915%0.154CC..Hα-helixtrans-65.3-38.2-172.4-177.957000112.1L214 F221 A241 F246 L247 V248L214-L244 HydrophobicContact CD1-CG 4.43Å; L214-L244 HydrophobicContact CD2-CD2 3.85Å; L214-L244 HydrophobicContact CD2-CG 4.18Å; F221-L244 HydrophobicContact CE1-CD2 4.28Å; F221-L244 HydrophobicContact CZ-CD2 4.22Å; A241-L244 HydrophobicContact CB-CB 4.37Å; A241-L244 PolarHBondContact O-N 3.25Å; L244-F246 VanDerWaalsContact C-N 3.3Å; L244-F246 PolarHBondContact O-N 3.16Å; L244-L247 WeakPolarHBondContact O-CB 3.41Å; L244-L247 PolarHBondContact O-N 3.23Å; L244-L247 VanDerWaalsContact O-N 3.16Å; L244-V248 WeakPolarHBondContact O-CG2 3.24Å; L244-V248 PolarHBondContact O-N 3.44Å
245G95.2Very high94.2Very high1 Ų129.6 Ų29.61%0.0115%0.154CC..Hα-helixtrans-72.8-24.2-179.700000113.3Y42 W243 L247 V248 A249Y42-G245 VanDerWaalsContact CE1-CA 3.5Å; Y42-G245 WeakPolarHBondContact OH-CA 3.28Å; Y42-G245 PolarHBondContact OH-N 3.06Å; W243-G245 PolarHBondContact O-N 2.89Å; G245-L247 VanDerWaalsContact C-N 3.32Å; G245-V248 PolarHBondContact O-N 3.46Å; G245-A249 WeakPolarHBondContact O-CB 3.13Å; G245-A249 PolarHBondContact O-N 3.08Å
246F97.4Very high94.7Very high0 Ų028.9 Ų28.90%015%0.151CC..Hα-helixtrans-68.5-31.7170.2-70.3-59.1000112.3V39 Y42 M43 S103 M106 A107 W242 W243 L244 S250V39-F246 HydrophobicContact CG1-CD1 4.41Å; V39-F246 HydrophobicContact CG1-CE1 4.36Å; Y42-F246 AromaticContact CD1-CD1 3.94Å; Y42-F246 HydrophobicContact CD1-CD1 3.94Å; Y42-F246 HydrophobicContact CD1-CD2 4.35Å; Y42-F246 AromaticContact CD1-CE1 3.79Å; Y42-F246 HydrophobicContact CD1-CE1 3.79Å; Y42-F246 HydrophobicContact CD1-CE2 4.22Å; Y42-F246 HydrophobicContact CD1-CG 4.19Å; Y42-F246 AromaticContact CD1-CZ 3.92Å; Y42-F246 HydrophobicContact CD1-CZ 3.92Å; Y42-F246 HydrophobicContact CE1-CD1 4.26Å; Y42-F246 AromaticContact CE1-CD2 3.89Å; Y42-F246 HydrophobicContact CE1-CD2 3.89Å; Y42-F246 HydrophobicContact CE1-CE1 4.29Å; Y42-F246 AromaticContact CE1-CE2 3.92Å; Y42-F246 HydrophobicContact CE1-CE2 3.92Å; Y42-F246 HydrophobicContact CE1-CG 4.04Å; Y42-F246 HydrophobicContact CE1-CZ 4.11Å; M43-F246 HydrophobicContact CB-CE1 4.36Å; M43-F246 HydrophobicContact CB-CZ 4.29Å; M43-F246 HydrophobicContact SD-CE1 4.39Å; M43-F246 HydrophobicContact SD-CZ 3.63Å; S103-F246 WeakPolarHBondContact O-CB 3.41Å; S103-F246 PolarHBondContact OG-O 3.41Å; S103-F246 VanDerWaalsContact OG-O 3.08Å; M106-F246 HydrophobicContact CB-CD1 3.89Å; M106-F246 HydrophobicContact CB-CD2 4.03Å; M106-F246 HydrophobicContact CB-CE1 4.03Å; M106-F246 HydrophobicContact CB-CE2 4.16Å; M106-F246 HydrophobicContact CB-CG 3.91Å; M106-F246 HydrophobicContact CB-CZ 4.18Å; M106-F246 HydrophobicContact CE-CE1 4.45Å; M106-F246 HydrophobicContact CE-CE2 4.39Å; M106-F246 HydrophobicContact CE-CZ 3.96Å; M106-F246 HydrophobicContact CG-CE1 4.4Å; A107-F246 HydrophobicContact CB-CB 3.95Å; W242-F246 HydrophobicContact CE3-CD2 4.07Å; W242-F246 AromaticContact CE3-CE2 3.82Å; W242-F246 HydrophobicContact CE3-CE2 3.82Å; W242-F246 HydrophobicContact CZ3-CD2 4.15Å; W242-F246 HydrophobicContact CZ3-CE2 4.05Å; W242-F246 VanDerWaalsContact O-CD2 3.31Å; W242-F246 WeakPolarHBondContact O-CD2 3.31Å; W243-F246 WeakPolarHBondContact O-CB 3.37Å; W243-F246 PolarHBondContact O-N 3.47Å; L244-F246 VanDerWaalsContact C-N 3.3Å; L244-F246 PolarHBondContact O-N 3.16Å; F246-S250 WeakPolarHBondContact O-CB 3.3Å; F246-S250 PolarHBondContact O-N 2.95Å; F246-S250 PolarHBondContact O-OG 3.18Å
247L96.9Very high95.3Very high47 Ų4727.3 Ų27.325%0.24614%0.143CC..Hα-helixtrans-71.5-43.4172.6-60-177.4000112L104 A107 F111 W243 L244 G245 S250 S251L104-L247 HydrophobicContact CD2-CD2 3.85Å; A107-L247 HydrophobicContact CB-CD2 3.81Å; A107-L247 HydrophobicContact CB-CG 4.22Å; F111-L247 HydrophobicContact CZ-CD1 4.21Å; W243-L247 HydrophobicContact CE3-CD1 3.64Å; W243-L247 HydrophobicContact CE3-CG 4.33Å; W243-L247 HydrophobicContact CZ3-CD1 3.51Å; W243-L247 PolarHBondContact O-N 3.39Å; L244-L247 WeakPolarHBondContact O-CB 3.41Å; L244-L247 PolarHBondContact O-N 3.23Å; L244-L247 VanDerWaalsContact O-N 3.16Å; G245-L247 VanDerWaalsContact C-N 3.32Å; L247-S250 WeakPolarHBondContact CA-OG 3.43Å; L247-S250 PolarHBondContact O-OG 2.83Å; L247-S251 WeakPolarHBondContact O-CB 3.43Å; L247-S251 PolarHBondContact O-N 2.82Å; L247-S251 PolarHBondContact O-OG 2.87Å
248V96.2Very high95.6Very high74 Ų7429.5 Ų29.545%0.44816%0.156SC..Hα-helixtrans-62.8-47.1175.71750000110.5L244 G245 S251 F252L244-V248 WeakPolarHBondContact O-CG2 3.24Å; L244-V248 PolarHBondContact O-N 3.44Å; G245-V248 PolarHBondContact O-N 3.46Å; V248-S251 PolarHBondContact O-N 3.25Å; V248-F252 PolarHBondContact O-N 3.12Å; V248-F252 VanDerWaalsContact O-N 3.09Å
249A95.7Very high95.8Very high1 Ų130 Ų301%0.00816%0.161CC..Hα-helixtrans-68.9-38.4-178.400000112.6L38 V39 G245 F252 L253L38-A249 HydrophobicContact CD2-CB 3.56Å; V39-A249 HydrophobicContact CG2-CB 3.62Å; G245-A249 WeakPolarHBondContact O-CB 3.13Å; G245-A249 PolarHBondContact O-N 3.08Å; A249-F252 PolarHBondContact O-N 3Å; A249-L253 WeakPolarHBondContact O-CB 3.4Å; A249-L253 PolarHBondContact O-N 2.9Å
250S96.9Very high96Very high3 Ų330 Ų302%0.02116%0.161CC..Hα-helixtrans-65.3-40.5174.153.90000112.2C100 L104 F246 L247 F252 L253 F254C100-S250 PolarHBondContact SG-O 3.31Å; C100-S250 VanDerWaalsContact SG-O 3.36Å; L104-S250 VanDerWaalsContact CD2-OG 3.24Å; L104-S250 WeakPolarHBondContact CD2-OG 3.49Å; F246-S250 WeakPolarHBondContact O-CB 3.3Å; F246-S250 PolarHBondContact O-N 2.95Å; F246-S250 PolarHBondContact O-OG 3.18Å; L247-S250 WeakPolarHBondContact CA-OG 3.43Å; L247-S250 PolarHBondContact O-OG 2.83Å; S250-F252 VanDerWaalsContact C-N 3.32Å; S250-F252 PolarHBondContact O-N 3.22Å; S250-L253 PolarHBondContact O-N 2.62Å; S250-F254 WeakPolarHBondContact O-CB 3.44Å; S250-F254 PolarHBondContact O-N 3.05Å
251S96.9Very high95.9Very high70 Ų7035.1 Ų35.149%0.4919%0.188SC..Hα-helixtrans-59.1-44.9174.3-58.60000111.3L247 V248 F254 L255L247-S251 WeakPolarHBondContact O-CB 3.43Å; L247-S251 PolarHBondContact O-N 2.82Å; L247-S251 PolarHBondContact O-OG 2.87Å; V248-S251 PolarHBondContact O-N 3.25Å; S251-F254 PolarHBondContact O-N 3.38Å; S251-L255 VanDerWaalsContact O-CG 3.32Å; S251-L255 WeakPolarHBondContact O-CG 3.5Å; S251-L255 PolarHBondContact O-N 3.31Å; S251-L255 VanDerWaalsContact O-N 3.07Å
252F96.3Very high95.9Very high67 Ų6741.3 Ų41.329%0.29422%0.215SC..Hα-helixtrans-67.4-38.9177.4-175.3-128.5000112.9L34 A35 V248 A249 S250 L255 T256L34-F252 HydrophobicContact CD2-CE1 3.55Å; L34-F252 HydrophobicContact CD2-CZ 4.14Å; A35-F252 HydrophobicContact CB-CD1 3.35Å; A35-F252 HydrophobicContact CB-CE1 3.43Å; A35-F252 VanDerWaalsContact CB-CE1 3.43Å; A35-F252 HydrophobicContact CB-CG 4.2Å; A35-F252 HydrophobicContact CB-CZ 4.34Å; V248-F252 PolarHBondContact O-N 3.12Å; V248-F252 VanDerWaalsContact O-N 3.09Å; A249-F252 PolarHBondContact O-N 3Å; S250-F252 VanDerWaalsContact C-N 3.32Å; S250-F252 PolarHBondContact O-N 3.22Å; F252-L255 PolarHBondContact O-N 3.48Å; F252-T256 HydrophobicContact CD2-CG2 4.25Å; F252-T256 HydrophobicContact CE2-CG2 3.85Å; F252-T256 HydrophobicContact CZ-CG2 4.07Å; F252-T256 WeakPolarHBondContact O-CG2 3.29Å; F252-T256 PolarHBondContact O-N 2.92Å; F252-T256 PolarHBondContact O-OG1 3.46Å
253L95.9Very high95.8Very high0 Ų041.5 Ų41.50%022%0.216CC..Hα-helixtrans-61.8-43.9172.2-90.1172.7000112.6L32 A35 Q36 V39 A99 C100 A249 S250 T256 A257L32-L253 HydrophobicContact CD1-CD2 3.97Å; A35-L253 HydrophobicContact CB-CD2 3.69Å; A35-L253 HydrophobicContact CB-CG 3.9Å; Q36-L253 HydrophobicContact CB-CD2 4.09Å; V39-L253 HydrophobicContact CG2-CD1 3.51Å; V39-L253 HydrophobicContact CG2-CG 4.43Å; A99-L253 HydrophobicContact CB-CD1 4.45Å; C100-L253 HydrophobicContact CB-CB 4.21Å; A249-L253 WeakPolarHBondContact O-CB 3.4Å; A249-L253 PolarHBondContact O-N 2.9Å; S250-L253 PolarHBondContact O-N 2.62Å; L253-T256 WeakPolarHBondContact CA-OG1 3.3Å; L253-T256 PolarHBondContact O-N 3.4Å; L253-T256 PolarHBondContact O-OG1 2.8Å; L253-A257 WeakPolarHBondContact O-CB 3.48Å; L253-A257 PolarHBondContact O-N 2.98Å
254F97.4Very high95.6Very high96 Ų9642.6 Ų42.642%0.42123%0.225SC..Hα-helixtrans-60.2-49.3177.9-179.6-103.9000111L97 S250 S251 T256 A257 L258L97-F254 HydrophobicContact CD2-CD2 3.87Å; L97-F254 HydrophobicContact CD2-CE2 4.06Å; S250-F254 WeakPolarHBondContact O-CB 3.44Å; S250-F254 PolarHBondContact O-N 3.05Å; S251-F254 PolarHBondContact O-N 3.38Å; F254-T256 VanDerWaalsContact C-N 3.3Å; F254-T256 PolarHBondContact O-N 3.15Å; F254-A257 WeakPolarHBondContact O-CB 3.21Å; F254-A257 PolarHBondContact O-N 3.31Å; F254-A257 VanDerWaalsContact O-N 3.1Å; F254-L258 HydrophobicContact CE1-CD1 4.11Å; F254-L258 HydrophobicContact CE1-CD2 4.27Å; F254-L258 HydrophobicContact CE1-CG 4.4Å; F254-L258 HydrophobicContact CE2-CD2 4.38Å; F254-L258 HydrophobicContact CZ-CD2 3.98Å; F254-L258 PolarHBondContact O-N 3.43Å
255L97.1Very high95.3Very high110 Ų11047 Ų4758%0.57624%0.239SC*.Hα-helixtrans-59.7-40.5178.2-69.1173.5000112.4S251 F252 A257 P259S251-L255 VanDerWaalsContact O-CG 3.32Å; S251-L255 WeakPolarHBondContact O-CG 3.5Å; S251-L255 PolarHBondContact O-N 3.31Å; S251-L255 VanDerWaalsContact O-N 3.07Å; F252-L255 PolarHBondContact O-N 3.48Å; L255-A257 VanDerWaalsContact C-N 3.31Å; L255-A257 PolarHBondContact O-N 3.26Å; L255-P259 WeakPolarHBondContact O-CD 3.5Å
256T96.3Very high94.9Very high11 Ų1153.5 Ų53.57%0.06727%0.269CS..Hα-helixtrans-76.3-16.6178.653.50000113.6L31 A35 F252 L253 F254 P259L31-T256 HydrophobicContact CB-CG2 3.84Å; A35-T256 HydrophobicContact CB-CG2 4.49Å; F252-T256 HydrophobicContact CD2-CG2 4.25Å; F252-T256 HydrophobicContact CE2-CG2 3.85Å; F252-T256 HydrophobicContact CZ-CG2 4.07Å; F252-T256 WeakPolarHBondContact O-CG2 3.29Å; F252-T256 PolarHBondContact O-N 2.92Å; F252-T256 PolarHBondContact O-OG1 3.46Å; L253-T256 WeakPolarHBondContact CA-OG1 3.3Å; L253-T256 PolarHBondContact O-N 3.4Å; L253-T256 PolarHBondContact O-OG1 2.8Å; F254-T256 VanDerWaalsContact C-N 3.3Å; F254-T256 PolarHBondContact O-N 3.15Å; T256-P259 WeakPolarHBondContact O-CD 3.13Å
257A96.6Very high94.5Very high4 Ų454 Ų543%0.03327%0.271CS..Hα-helixtrans-79.8-33174.200000113.3A96 L97 L253 F254 L255 P259 Y260A96-A257 HydrophobicContact CB-CB 3.68Å; L97-A257 HydrophobicContact CD2-CB 4.05Å; L97-A257 HydrophobicContact CG-CB 4.24Å; L253-A257 WeakPolarHBondContact O-CB 3.48Å; L253-A257 PolarHBondContact O-N 2.98Å; F254-A257 WeakPolarHBondContact O-CB 3.21Å; F254-A257 PolarHBondContact O-N 3.31Å; F254-A257 VanDerWaalsContact O-N 3.1Å; L255-A257 VanDerWaalsContact C-N 3.31Å; L255-A257 PolarHBondContact O-N 3.26Å; A257-P259 VanDerWaalsContact C-CD 3.47Å; A257-Y260 WeakPolarHBondContact O-CB 3.45Å; A257-Y260 PolarHBondContact O-N 3.29Å; A257-Y260 VanDerWaalsContact O-N 3.13Å
258L95.3Very high94Very high65 Ų6555.5 Ų55.534%0.3428%0.284SS..G310 helixtrans-55-41.8-175.7-65.4175.6000115.1F254 Y260 L261F254-L258 HydrophobicContact CE1-CD1 4.11Å; F254-L258 HydrophobicContact CE1-CD2 4.27Å; F254-L258 HydrophobicContact CE1-CG 4.4Å; F254-L258 HydrophobicContact CE2-CD2 4.38Å; F254-L258 HydrophobicContact CZ-CD2 3.98Å; F254-L258 PolarHBondContact O-N 3.43Å; L258-Y260 PolarHBondContact O-N 3Å; L258-L261 HydrophobicContact CD2-CD1 4.42Å; L258-L261 WeakPolarHBondContact O-CB 3.32Å; L258-L261 PolarHBondContact O-N 3.29Å; L258-L261 VanDerWaalsContact O-N 3.12Å
259P95.3Very high93.5Very high26 Ų2659.1 Ų59.117%0.16929%0.294CS..G310 helixtrans-54.2-28.7177.9-30.138000114.5F19 C28 L255 T256 A257 L261 F262 F263F19-P259 HydrophobicContact CE1-CB 4.11Å; C28-P259 HydrophobicContact CB-CB 4.28Å; L255-P259 WeakPolarHBondContact O-CD 3.5Å; T256-P259 WeakPolarHBondContact O-CD 3.13Å; A257-P259 VanDerWaalsContact C-CD 3.47Å; P259-L261 PolarHBondContact O-N 3.23Å; P259-F262 PolarHBondContact O-N 3.32Å; P259-F263 HydrophobicContact CB-CE2 3.9Å; P259-F263 VanDerWaalsContact O-CD2 3.29Å; P259-F263 WeakPolarHBondContact O-CD2 3.38Å; P259-F263 PolarHBondContact O-N 3.23Å
260Y94.9Very high92.9Very high1 Ų160.7 Ų60.70%0.00430%0.301CS..G310 helixtrans-70.3-13.5-177.8-73-88.4000114.8F25 H29 L32 P89 I92 A257 L258 F262 F263F25-Y260 HydrophobicContact CE2-CD1 4.44Å; F25-Y260 AromaticContact CE2-CE1 3.71Å; F25-Y260 HydrophobicContact CE2-CE1 3.71Å; F25-Y260 HydrophobicContact CZ-CE1 4.12Å; H29-Y260 WeakPolarHBondContact CA-OH 3.35Å; H29-Y260 WeakPolarHBondContact CB-OH 3.31Å; H29-Y260 VanDerWaalsContact CG-OH 3.3Å; H29-Y260 PolarHBondContact ND1-OH 2.6Å; L32-Y260 HydrophobicContact CB-CE2 4.27Å; L32-Y260 HydrophobicContact CD2-CD2 4.14Å; L32-Y260 HydrophobicContact CD2-CE2 3.44Å; L32-Y260 VanDerWaalsContact CD2-CE2 3.44Å; L32-Y260 HydrophobicContact CG-CE2 4.44Å; P89-Y260 HydrophobicContact CB-CD1 4.09Å; P89-Y260 WeakPolarHBondContact O-CB 3.24Å; P89-Y260 VanDerWaalsContact O-CD1 3.3Å; P89-Y260 WeakPolarHBondContact O-CD1 3.47Å; I92-Y260 HydrophobicContact CB-CD1 3.79Å; I92-Y260 HydrophobicContact CB-CE1 3.75Å; I92-Y260 HydrophobicContact CD1-CD1 4.47Å; I92-Y260 HydrophobicContact CD1-CE1 3.88Å; I92-Y260 HydrophobicContact CG1-CE1 4.44Å; I92-Y260 HydrophobicContact CG2-CD1 3.7Å; I92-Y260 HydrophobicContact CG2-CD2 4.45Å; I92-Y260 HydrophobicContact CG2-CE1 3.33Å; I92-Y260 HydrophobicContact CG2-CE2 4.15Å; I92-Y260 HydrophobicContact CG2-CG 4.24Å; A257-Y260 WeakPolarHBondContact O-CB 3.45Å; A257-Y260 PolarHBondContact O-N 3.29Å; A257-Y260 VanDerWaalsContact O-N 3.13Å; L258-Y260 PolarHBondContact O-N 3Å; Y260-F262 VanDerWaalsContact C-N 3.26Å; Y260-F263 HydrophobicContact CD1-CD2 4.27Å; Y260-F263 HydrophobicContact CG-CD2 4.49Å
261L92.4Very high91.9Very high107 Ų10767.2 Ų67.256%0.5634%0.336SS*.G310 helixtrans-71.7-24.4170.3-59.3177.4000112.1L258 P259L258-L261 HydrophobicContact CD2-CD1 4.42Å; L258-L261 WeakPolarHBondContact O-CB 3.32Å; L258-L261 PolarHBondContact O-N 3.29Å; L258-L261 VanDerWaalsContact O-N 3.12Å; P259-L261 PolarHBondContact O-N 3.23Å
262F93.8Very high90.1Very high130 Ų13069 Ų6957%0.5734%0.336SS*.THydrogen-bonded Turntrans-104-18.3-172.4-56.1-77.1000114F19 P259 Y260F19-F262 HydrophobicContact CB-CB 4.35Å; F19-F262 HydrophobicContact CD1-CB 3.84Å; F19-F262 HydrophobicContact CD2-CB 3.74Å; F19-F262 HydrophobicContact CD2-CG 4.44Å; F19-F262 HydrophobicContact CE1-CB 4.02Å; F19-F262 HydrophobicContact CE1-CD2 4.35Å; F19-F262 HydrophobicContact CE2-CB 3.92Å; F19-F262 HydrophobicContact CE2-CD2 4.46Å; F19-F262 HydrophobicContact CE2-CG 4.16Å; F19-F262 HydrophobicContact CG-CB 3.69Å; F19-F262 HydrophobicContact CZ-CB 4.05Å; F19-F262 HydrophobicContact CZ-CD2 4.08Å; F19-F262 HydrophobicContact CZ-CG 4.2Å; P259-F262 PolarHBondContact O-N 3.32Å; Y260-F262 VanDerWaalsContact C-N 3.26Å
263F94.1Very high87.8Confident5 Ų575 Ų752%0.02237%0.366CS..SBendtrans-67.8132.6177-76.6-63.7000111.4F19 V24 F25 C28 H87 P89 P259 Y260 M267F19-F263 HydrophobicContact CB-CD1 4.03Å; F19-F263 HydrophobicContact CB-CE1 4.16Å; F19-F263 HydrophobicContact CD1-CD1 4.3Å; F19-F263 AromaticContact CD1-CE1 3.99Å; F19-F263 HydrophobicContact CD1-CE1 3.99Å; F19-F263 HydrophobicContact CD1-CE2 4.28Å; F19-F263 AromaticContact CD1-CZ 3.96Å; F19-F263 HydrophobicContact CD1-CZ 3.96Å; F19-F263 VanDerWaalsContact O-CD1 3.25Å; F19-F263 WeakPolarHBondContact O-CD1 3.23Å; V24-F263 HydrophobicContact CG1-CE1 4.46Å; V24-F263 HydrophobicContact CG1-CZ 4.16Å; F25-F263 HydrophobicContact CB-CD1 4.4Å; F25-F263 HydrophobicContact CB-CE1 3.8Å; F25-F263 HydrophobicContact CB-CZ 3.99Å; F25-F263 AromaticContact CD2-CD1 3.94Å; F25-F263 HydrophobicContact CD2-CD1 3.94Å; F25-F263 AromaticContact CD2-CD2 3.92Å; F25-F263 HydrophobicContact CD2-CD2 3.92Å; F25-F263 HydrophobicContact CD2-CE1 4.02Å; F25-F263 HydrophobicContact CD2-CE2 4Å; F25-F263 AromaticContact CD2-CG 3.92Å; F25-F263 HydrophobicContact CD2-CG 3.92Å; F25-F263 HydrophobicContact CD2-CZ 4.06Å; F25-F263 HydrophobicContact CE2-CD2 4.4Å; F25-F263 HydrophobicContact CG-CE1 4.43Å; F25-F263 HydrophobicContact CG-CZ 4.49Å; C28-F263 HydrophobicContact CB-CE2 4.04Å; C28-F263 HydrophobicContact CB-CZ 4.22Å; H87-F263 PolarHBondContact CE1-O 3.48Å; P89-F263 HydrophobicContact CB-CB 3.76Å; P89-F263 HydrophobicContact CG-CB 4.06Å; P259-F263 HydrophobicContact CB-CE2 3.9Å; P259-F263 VanDerWaalsContact O-CD2 3.29Å; P259-F263 WeakPolarHBondContact O-CD2 3.38Å; P259-F263 PolarHBondContact O-N 3.23Å; Y260-F263 HydrophobicContact CD1-CD2 4.27Å; Y260-F263 HydrophobicContact CG-CD2 4.49Å; F263-M267 HydrophobicContact CD1-CE 3.99Å; F263-M267 HydrophobicContact CE1-CE 4.26Å
264P92.1Very high85.4Confident38 Ų3878.1 Ų78.125%0.24740%0.398CS..  trans-70.4164.7-179.731.5-36.3000111.8F19 Y179 E266F19-P264 WeakPolarHBondContact O-CD 3Å; Y179-P264 PolarHBondContact OH-O 3Å; Y179-P264 VanDerWaalsContact OH-O 3.08Å; P264-E266 VanDerWaalsContact C-N 3.27Å; P264-E266 WeakPolarHBondContact CB-O 3.3Å; P264-E266 WeakPolarHBondContact CG-O 3.47Å; P264-E266 PolarHBondContact O-N 3.36Å
265R89.4Confident82.7Confident132 Ų13279.6 Ų79.650%0.49841%0.41SS..SBendtrans-61.6-41.2173-174.1179.4176163.10.5111.5H87H87-R265 HydrophobicContact CB-CG 4.45Å; H87-R265 PolarHBondContact CE1-N 2Å; H87-R265 VanDerWaalsContact CE1-N 3.35Å; H87-R265 WeakPolarHBondContact NE2-CA 3.39Å; H87-R265 PolarHBondContact NE2-N 3.49Å
266E86.9Confident79.9Confident137 Ų13783.9 Ų83.964%0.6443%0.427SS*.SBendtrans-128.9134.4-178.6-58.7179.3-178.600109.2Y183 P264Y183-E266 HydrophobicContact CE1-CB 4.42Å; Y183-E266 VanDerWaalsContact OH-CA 3.3Å; Y183-E266 WeakPolarHBondContact OH-CA 3.19Å; P264-E266 VanDerWaalsContact C-N 3.27Å; P264-E266 WeakPolarHBondContact CB-O 3.3Å; P264-E266 WeakPolarHBondContact CG-O 3.47Å; P264-E266 PolarHBondContact O-N 3.36Å
267M87.3Confident77.3Confident9 Ų991.8 Ų91.84%0.04446%0.463CS..  trans-105.4147.8-179.6-170171.7-79.300109.6F19 S21 I22 F25 Y179 Y183 F263 K269F19-M267 WeakPolarHBondContact O-CE 3.06Å; S21-M267 VanDerWaalsContact C-SD 3.55Å; I22-M267 WeakPolarHBondContact CA-SD 3.44Å; I22-M267 HydrophobicContact CB-SD 3.82Å; I22-M267 HydrophobicContact CD1-SD 3.91Å; I22-M267 HydrophobicContact CG1-SD 4.48Å; I22-M267 PolarHBondContact N-SD 3.08Å; F25-M267 HydrophobicContact CB-CE 4.2Å; Y179-M267 HydrophobicContact CE1-CB 4.45Å; Y179-M267 HydrophobicContact CE1-CE 4.03Å; Y179-M267 HydrophobicContact CE1-SD 4.43Å; Y183-M267 HydrophobicContact CD1-CB 3.87Å; Y183-M267 WeakPolarHBondContact CD1-O 2.87Å; Y183-M267 HydrophobicContact CD2-CB 4.01Å; Y183-M267 HydrophobicContact CE1-CB 4.28Å; Y183-M267 VanDerWaalsContact CE1-N 3.34Å; Y183-M267 WeakPolarHBondContact CE1-O 3.42Å; Y183-M267 HydrophobicContact CE2-CB 4.45Å; Y183-M267 HydrophobicContact CG-CB 3.75Å; F263-M267 HydrophobicContact CD1-CE 3.99Å; F263-M267 HydrophobicContact CE1-CE 4.26Å; M267-K269 PolarHBondContact O-N 3.4Å
268P87.2Confident74.4Confident80 Ų8096.8 Ų96.852%0.51950%0.498SS..PPolyproline II helixtrans-57.1129.9166-20.632.5000109.1
269K85.5Confident71.9Confident149 Ų149105.9 Ų105.965%0.64853%0.528SS*.PPolyproline II helixtrans-60140.2174.4-70.8-172175-177.10109.5D182 Y183 M267 N271D182-K269 WeakPolarHBondContact O-CE 3.12Å; Y183-K269 HydrophobicContact CD1-CG 4.37Å; M267-K269 PolarHBondContact O-N 3.4Å; K269-N271 PolarHBondContact O-N 2.85Å
270E84.4Confident69.3Low35 Ų35109.9 Ų109.916%0.16455%0.552CS.*PPolyproline II helixtrans-60119.4173.8-171.1-178.8-144.800109.2I22 K23 Y183 S185 N188 Y192 E272I22-E270 HydrophobicContact CG2-CB 4.17Å; I22-E270 HydrophobicContact CG2-CG 4.37Å; K23-E270 WeakPolarHBondContact CE-OE1 3.14Å; Y183-E270 PolarHBondContact O-N 3.42Å; S185-E270 WeakPolarHBondContact CB-OE2 3.43Å; S185-E270 PolarHBondContact N-OE2 3.04Å; S185-E270 VanDerWaalsContact N-OE2 3.13Å; S185-E270 PolarHBondContact OG-OE2 3.43Å; N188-E270 WeakPolarHBondContact CB-OE2 3.4Å; N188-E270 VanDerWaalsContact ND2-CD 3.29Å; N188-E270 PolarHBondContact ND2-OE1 3.28Å; N188-E270 VanDerWaalsContact ND2-OE1 3.11Å; N188-E270 PolarHBondContact ND2-OE2 3.39Å; Y192-E270 PolarHBondContact OH-OE1 3.44Å; E270-E272 PolarHBondContact O-N 3.11Å
271N74.4Confident66.6Low140 Ų140116.5 Ų116.575%0.74959%0.587SS**PPolyproline II helixtrans-65135.2179.5-67.8-21.6000109.9K269 E273K269-N271 PolarHBondContact O-N 2.85Å; N271-E273 PolarHBondContact O-N 3.32Å
272E58.8Low64.1Low107 Ų107118.2 Ų118.250%0.560%0.596SS.*  trans-71.293.3167-70.4175.8165.400108E270 G274E270-E272 PolarHBondContact O-N 3.11Å; E272-G274 PolarHBondContact O-N 3.01Å
273E48.6Very low61.2Low194 Ų194120.9 Ų120.991%0.90761%0.61SS**THydrogen-bonded Turntrans-67.483.4163.1-71.7178.6178.600107.4N271N271-E273 PolarHBondContact O-N 3.32Å
274G45.6Very low58.4Low65 Ų65125.3 Ų125.367%0.6764%0.639SS**THydrogen-bonded Turntrans165.7-33.2177.500000117.4E272E272-G274 PolarHBondContact O-N 3.01Å
275D41.1Very low55.5Low127 Ų127128.5 Ų128.568%0.67966%0.66SS**  trans-112.373.9-170.8-72.1-19.7000111.8
276Q38.1Very low53Low200 Ų200127.4 Ų127.494%0.93567%0.67SS**  trans-98.78.2165.8-119.6-1785.900113.5
277E41.1Very low50.4Low176 Ų176129.8 Ų129.882%0.82268%0.683SS**SBendtrans-111.3127.6168.7-84.4-178.7153.200110.6
278S36.9Very low47.9Very low110 Ų110135 Ų13577%0.76972%0.715SS**  trans85.252.5-177.575.70000117.9T280S278-T280 PolarHBondContact O-N 3.16Å
279R41.3Very low45.5Very low256 Ų256136.2 Ų136.297%0.96672%0.718SS**  trans-82.475146.2-94.6-174.2170175-2.9110.2
280T41.5Very low43.6Very low110 Ų110133.8 Ų133.868%0.67572%0.717SS**  trans-145.9133.4153.110.70000107.4S278S278-T280 PolarHBondContact O-N 3.16Å
281D38.2Very low41.8Very low140 Ų140135.3 Ų135.375%0.74973%0.729SS**SBendtrans94.6103.9163.1-50.6-29.7000118.3
282I39.7Very low40.4Very low143 Ų143136.5 Ų136.573%0.73372%0.723SS**  trans67.686149.7-47.3166.5000113.1P284I282-P284 WeakPolarHBondContact O-CD 3.29Å
283E32.9Very low39.9Very low185 Ų185138.4 Ų138.486%0.86474%0.736SS**  trans-52111.2146.6-147.9172.9-168.900105.8
284P35.7Very low40.4Very low98 Ų98131.6 Ų131.664%0.63671%0.706SS**  trans-55.7135.7170.623.3-30.1000105.6I282I282-P284 WeakPolarHBondContact O-CD 3.29Å
285P31.1Very low41.5Very low105 Ų105132.6 Ų132.668%0.68270%0.699SS**  trans-49138.4178.821.3-31.7000107M287P285-M287 PolarHBondContact O-N 2.88Å
286P36.8Very low42.7Very low110 Ų110129.1 Ų129.171%0.71468%0.68SS**  trans-50.5115.9173.821.9-30.5000104.6T288P286-T288 PolarHBondContact O-N 3.47Å
287M32.9Very low44.2Very low186 Ų186126 Ų12692%0.91667%0.669SS**  trans-55101.9167.3-101.8-170.7163.300102.8P285 D289P285-M287 PolarHBondContact O-N 2.88Å; M287-D289 PolarHBondContact O-N 2.87Å
288T33.3Very low45.8Very low118 Ų118122.6 Ų122.672%0.72465%0.654SS**  trans-59.293.7167.230.70000103P286 P290P286-T288 PolarHBondContact O-N 3.47Å; T288-P290 WeakPolarHBondContact O-CD 3.39Å
289D38.3Very low47.5Very low106 Ų106119.4 Ų119.457%0.56763%0.626SS**  trans-49.1112.5168.3-112.4-29.5000104.4M287 V291 R292M287-D289 PolarHBondContact O-N 2.87Å; D289-V291 PolarHBondContact O-N 2.72Å; D289-R292 PolarHBondContact O-N 3.45Å
290P44.2Very low49.1Very low99 Ų99110.7 Ų110.764%0.64360%0.598SS**G310 helixtrans-59.6-10.9-177.321.2-30.3000111.5T288 L294T288-P290 WeakPolarHBondContact O-CD 3.39Å; P290-L294 WeakPolarHBondContact O-CD1 3.41Å
291V48.4Very low50.9Low67 Ų67114 Ų11441%0.40660%0.603SS.*G310 helixtrans-71.2-23.4174.2-168.90000113.4D289 D293 L294D289-V291 PolarHBondContact O-N 2.72Å; V291-D293 VanDerWaalsContact C-N 3.26Å; V291-D293 PolarHBondContact O-N 2.87Å; V291-L294 PolarHBondContact O-N 3.36Å
292R44.1Very low52.4Low165 Ų165109 Ų10962%0.62358%0.579SS**G310 helixtrans-66.5-26.2-179.6-92.2-176.4172.8-178.2-0.1113.3R85 D289R85-R292 PolarHBondContact NH2-O 3.06Å; D289-R292 PolarHBondContact O-N 3.45Å
293D47.4Very low54.1Low146 Ų146104.6 Ų104.678%0.78156%0.555SS**G310 helixtrans-105.3-0-179.9-66.8-31.9000114.1V291V291-D293 VanDerWaalsContact C-N 3.26Å; V291-D293 PolarHBondContact O-N 2.87Å
294L59.1Low56.3Low51 Ų5199.5 Ų99.527%0.26754%0.538SS..  trans-74.1135176.7-104.180.2000111.4F81 P290 V291 Q298 F299F81-L294 WeakPolarHBondContact CE2-O 3.04Å; P290-L294 WeakPolarHBondContact O-CD1 3.41Å; V291-L294 PolarHBondContact O-N 3.36Å; L294-Q298 HydrophobicContact CD2-CB 4.01Å; L294-Q298 HydrophobicContact CG-CB 4.08Å; L294-F299 HydrophobicContact CD2-CB 4.39Å
295T70.5Confident58.3Low87 Ų87104.9 Ų104.953%0.53455%0.546SS..  trans-70.7145.7167.4-47.40000108.9L297 Q298 F299T295-L297 PolarHBondContact O-N 2.87Å; T295-L297 VanDerWaalsContact O-N 3.08Å; T295-Q298 VanDerWaalsContact N-OE1 3.1Å; T295-Q298 WeakPolarHBondContact O-CA 3.45Å; T295-Q298 WeakPolarHBondContact O-CB 3.4Å; T295-Q298 PolarHBondContact O-N 3Å; T295-Q298 PolarHBondContact OG1-OE1 3.44Å; T295-F299 PolarHBondContact O-N 3.5Å; T295-F299 VanDerWaalsContact O-N 3.08Å
296L66.1Low60.2Low53 Ų53102.6 Ų102.628%0.27753%0.527SS..Hα-helixtrans-50.6-38.8179.9-167.5159.7000112F78 F81 F82 F299 L300F78-L296 HydrophobicContact CD1-CD1 4.41Å; F78-L296 HydrophobicContact CE1-CD2 4.36Å; F81-L296 HydrophobicContact CD1-CD1 4.15Å; F81-L296 HydrophobicContact CD1-CG 4.34Å; F81-L296 HydrophobicContact CE1-CB 4.04Å; F81-L296 HydrophobicContact CE1-CD1 4.14Å; F81-L296 HydrophobicContact CE1-CG 4.28Å; F81-L296 HydrophobicContact CZ-CB 4Å; F82-L296 HydrophobicContact CE2-CD1 4.38Å; F82-L296 HydrophobicContact CZ-CD1 3.89Å; L296-F299 PolarHBondContact O-N 3.28Å; L296-L300 HydrophobicContact CD2-CD1 3.43Å; L296-L300 VanDerWaalsContact CD2-CD1 3.43Å; L296-L300 HydrophobicContact CD2-CG 4.01Å; L296-L300 PolarHBondContact O-N 2.87Å
297L69.1Low62.1Low134 Ų13497.8 Ų97.870%0.70250%0.496SS*.Hα-helixtrans-64.4-38176.3-165.874.6000113.1T295 K301T295-L297 PolarHBondContact O-N 2.87Å; T295-L297 VanDerWaalsContact O-N 3.08Å; L297-K301 VanDerWaalsContact O-CB 3.29Å; L297-K301 WeakPolarHBondContact O-CB 3.3Å; L297-K301 PolarHBondContact O-N 3.19Å
298Q75.2Confident64.3Low106 Ų10694.5 Ų94.550%0.49548%0.482SS..Hα-helixtrans-70.8-36.8177.3-69.7170.2-26.400111.2L294 T295 K301 S302L294-Q298 HydrophobicContact CD2-CB 4.01Å; L294-Q298 HydrophobicContact CG-CB 4.08Å; T295-Q298 VanDerWaalsContact N-OE1 3.1Å; T295-Q298 WeakPolarHBondContact O-CA 3.45Å; T295-Q298 WeakPolarHBondContact O-CB 3.4Å; T295-Q298 PolarHBondContact O-N 3Å; T295-Q298 PolarHBondContact OG1-OE1 3.44Å; Q298-K301 PolarHBondContact O-N 3.12Å; Q298-S302 WeakPolarHBondContact O-CB 3.37Å; Q298-S302 PolarHBondContact O-N 3.39Å; Q298-S302 PolarHBondContact O-OG 2.85Å; Q298-S302 VanDerWaalsContact O-OG 3.06Å
299F72Confident66.4Low43 Ų4396.1 Ų96.119%0.18948%0.475CS..Hα-helixtrans-65.1-46.8174.1177.2-100.7000111.7V77 F81 L294 T295 L296 K301 S302 F303V77-F299 HydrophobicContact CG1-CE1 3.91Å; F81-F299 HydrophobicContact CD2-CG 4.49Å; L294-F299 HydrophobicContact CD2-CB 4.39Å; T295-F299 PolarHBondContact O-N 3.5Å; T295-F299 VanDerWaalsContact O-N 3.08Å; L296-F299 PolarHBondContact O-N 3.28Å; F299-K301 VanDerWaalsContact C-N 3.3Å; F299-K301 PolarHBondContact O-N 3.38Å; F299-S302 PolarHBondContact O-N 3.33Å; F299-S302 PolarHBondContact O-OG 2.84Å; F299-S302 VanDerWaalsContact O-OG 3.09Å; F299-F303 HydrophobicContact CZ-CD2 4.49Å; F299-F303 WeakPolarHBondContact O-CB 3.49Å; F299-F303 PolarHBondContact O-N 3.38Å
300L75.3Confident68.3Low72 Ų7291.6 Ų91.638%0.37745%0.451SS..Hα-helixtrans-63.7-34.5176-75.7175.8000112.8V77 L296 P304V77-L300 HydrophobicContact CG1-CD2 4.31Å; L296-L300 HydrophobicContact CD2-CD1 3.43Å; L296-L300 VanDerWaalsContact CD2-CD1 3.43Å; L296-L300 HydrophobicContact CD2-CG 4.01Å; L296-L300 PolarHBondContact O-N 2.87Å; L300-P304 WeakPolarHBondContact O-CD 3.49Å
301K77.8Confident70.1Confident179 Ų17989 Ų8978%0.77843%0.431SS*.Hα-helixtrans-75.2-30.9179-167173.8-177.2176.80112.8L297 Q298 F299L297-K301 VanDerWaalsContact O-CB 3.29Å; L297-K301 WeakPolarHBondContact O-CB 3.3Å; L297-K301 PolarHBondContact O-N 3.19Å; Q298-K301 PolarHBondContact O-N 3.12Å; F299-K301 VanDerWaalsContact C-N 3.3Å; F299-K301 PolarHBondContact O-N 3.38Å
302S71.1Confident71.7Confident37 Ų3790 Ų9026%0.25944%0.441SS..Hα-helixtrans-83.8-28178.263.60000113Q298 F299 R305 I306Q298-S302 WeakPolarHBondContact O-CB 3.37Å; Q298-S302 PolarHBondContact O-N 3.39Å; Q298-S302 PolarHBondContact O-OG 2.85Å; Q298-S302 VanDerWaalsContact O-OG 3.06Å; F299-S302 PolarHBondContact O-N 3.33Å; F299-S302 PolarHBondContact O-OG 2.84Å; F299-S302 VanDerWaalsContact O-OG 3.09Å; S302-R305 PolarHBondContact O-N 3.25Å; S302-I306 WeakPolarHBondContact O-CG1 3.29Å; S302-I306 PolarHBondContact O-N 2.93Å; S302-I306 VanDerWaalsContact O-N 3.15Å
303F75.2Confident73.7Confident49 Ų4983.3 Ų83.322%0.21542%0.424CS..Hα-helixtrans-53.4-48.8-176.8-177.5-90.9000114.9F299 R305 I306 A307 F532 M539F299-F303 HydrophobicContact CZ-CD2 4.49Å; F299-F303 WeakPolarHBondContact O-CB 3.49Å; F299-F303 PolarHBondContact O-N 3.38Å; F303-R305 VanDerWaalsContact C-N 3.29Å; F303-R305 PolarHBondContact O-N 3.33Å; F303-I306 PolarHBondContact O-N 3.35Å; F303-A307 HydrophobicContact CE1-CB 4.4Å; F303-A307 VanDerWaalsContact O-CB 3.24Å; F303-A307 WeakPolarHBondContact O-CB 3.47Å; F303-A307 PolarHBondContact O-N 3.29Å; F303-F532 AromaticContact CD2-CE2 3.72Å; F303-F532 HydrophobicContact CD2-CE2 3.72Å; F303-F532 HydrophobicContact CD2-CZ 4.29Å; F303-F532 AromaticContact CE2-CE2 3.69Å; F303-F532 HydrophobicContact CE2-CE2 3.69Å; F303-F532 HydrophobicContact CE2-CZ 4.17Å; F303-M539 HydrophobicContact CE1-SD 4.25Å; F303-M539 HydrophobicContact CZ-SD 4.16Å
304P78.3Confident75.6Confident79 Ų7979.4 Ų79.451%0.51341%0.406SS..Hα-helixtrans-62.9-36.6-178.6-20.731.8000112.4L300 L308L300-P304 WeakPolarHBondContact O-CD 3.49Å; P304-L308 VanDerWaalsContact O-CB 3.27Å; P304-L308 WeakPolarHBondContact O-CB 3.23Å; P304-L308 PolarHBondContact O-N 2.81Å
305R78.9Confident77.1Confident211 Ų21177.2 Ų77.280%0.79640%0.395SS*.Hα-helixtrans-68.7-43.2-179.7-170.8178.3-177.4-179.20.7111.3S302 F303 R309S302-R305 PolarHBondContact O-N 3.25Å; F303-R305 VanDerWaalsContact C-N 3.29Å; F303-R305 PolarHBondContact O-N 3.33Å; R305-R309 WeakPolarHBondContact O-CB 3.36Å; R305-R309 PolarHBondContact O-N 3.31Å
306I70.8Confident78.1Confident57 Ų5773.4 Ų73.429%0.29237%0.371SS..Hα-helixtrans-69.8-41.9177.6-55.4168000109.6S302 F303 L308 R309 T310 F532S302-I306 WeakPolarHBondContact O-CG1 3.29Å; S302-I306 PolarHBondContact O-N 2.93Å; S302-I306 VanDerWaalsContact O-N 3.15Å; F303-I306 PolarHBondContact O-N 3.35Å; I306-L308 PolarHBondContact O-N 3.25Å; I306-R309 WeakPolarHBondContact O-CB 3.38Å; I306-R309 PolarHBondContact O-N 3.16Å; I306-T310 PolarHBondContact O-N 3.36Å; I306-T310 PolarHBondContact O-OG1 2.66Å; I306-T310 VanDerWaalsContact O-OG1 3.07Å; I306-F532 VanDerWaalsContact C-CE1 3.49Å; I306-F532 HydrophobicContact CB-CE1 4.04Å; I306-F532 HydrophobicContact CB-CE2 4.18Å; I306-F532 HydrophobicContact CB-CZ 3.74Å; I306-F532 HydrophobicContact CG2-CD1 3.69Å; I306-F532 HydrophobicContact CG2-CD2 4.16Å; I306-F532 HydrophobicContact CG2-CE1 3.43Å; I306-F532 VanDerWaalsContact CG2-CE1 3.43Å; I306-F532 HydrophobicContact CG2-CE2 3.92Å; I306-F532 HydrophobicContact CG2-CG 4.05Å; I306-F532 HydrophobicContact CG2-CZ 3.56Å
307A75.8Confident79.5Confident8 Ų873.7 Ų73.77%0.06637%0.372CS..Hα-helixtrans-58-46.6175.400000111.5F303 R309 T310 L311 F532 V536F303-A307 HydrophobicContact CE1-CB 4.4Å; F303-A307 VanDerWaalsContact O-CB 3.24Å; F303-A307 WeakPolarHBondContact O-CB 3.47Å; F303-A307 PolarHBondContact O-N 3.29Å; A307-R309 PolarHBondContact O-N 3.33Å; A307-T310 PolarHBondContact O-N 3.09Å; A307-L311 WeakPolarHBondContact O-CB 3.32Å; A307-L311 VanDerWaalsContact O-CG 3.24Å; A307-L311 WeakPolarHBondContact O-CG 3.46Å; A307-L311 PolarHBondContact O-N 3.35Å; A307-F532 HydrophobicContact CB-CE1 4.37Å; A307-F532 HydrophobicContact CB-CZ 3.94Å; A307-F532 VanDerWaalsContact N-CZ 3.28Å; A307-V536 HydrophobicContact CB-CG2 4.35Å
308L78.8Confident80.7Confident118 Ų11868.9 Ų68.962%0.61835%0.347SS*.Hα-helixtrans-65.5-39.2178.7-166.570.4000112.1P304 I306 L311 S312P304-L308 VanDerWaalsContact O-CB 3.27Å; P304-L308 WeakPolarHBondContact O-CB 3.23Å; P304-L308 PolarHBondContact O-N 2.81Å; I306-L308 PolarHBondContact O-N 3.25Å; L308-L311 PolarHBondContact O-N 3.4Å; L308-S312 WeakPolarHBondContact O-CB 3.27Å; L308-S312 PolarHBondContact O-N 3.12Å; L308-S312 PolarHBondContact O-OG 3.06Å
309R78.7Confident81.7Confident151 Ų15163.9 Ų63.957%0.5732%0.324SS*.Hα-helixtrans-60.1-46.4173.6-172-179.2771734.5111.3R305 I306 A307 S312 D529R305-R309 WeakPolarHBondContact O-CB 3.36Å; R305-R309 PolarHBondContact O-N 3.31Å; I306-R309 WeakPolarHBondContact O-CB 3.38Å; I306-R309 PolarHBondContact O-N 3.16Å; A307-R309 PolarHBondContact O-N 3.33Å; R309-S312 WeakPolarHBondContact O-CB 3.42Å; R309-S312 PolarHBondContact O-N 2.96Å; R309-D529 IonicContact CZ-OD2 3.73Å; R309-D529 IonicContact NE-OD2 3.93Å; R309-D529 IonicContact NH2-OD1 3.08Å; R309-D529 PolarHBondContact NH2-OD1 3.45Å; R309-D529 IonicContact NH2-OD2 3.65Å; R309-D529 PolarHBondContact NH2-OD2 2.81Å
310T77.5Confident82.8Confident11 Ų1161.8 Ų61.87%0.06732%0.315CS..Hα-helixtrans-65.1-42.3178.1-54.80000111.6I306 A307 S312 G313 Y316 F532 A533I306-T310 PolarHBondContact O-N 3.36Å; I306-T310 PolarHBondContact O-OG1 2.66Å; I306-T310 VanDerWaalsContact O-OG1 3.07Å; A307-T310 PolarHBondContact O-N 3.09Å; T310-S312 PolarHBondContact O-N 3.29Å; T310-G313 PolarHBondContact O-N 3.44Å; T310-Y316 HydrophobicContact CG2-CD1 4.08Å; T310-Y316 HydrophobicContact CG2-CE1 3.7Å; T310-Y316 HydrophobicContact CG2-CE2 4.5Å; T310-Y316 VanDerWaalsContact O-CD1 3.3Å; T310-Y316 WeakPolarHBondContact O-CD1 3.44Å; T310-F532 HydrophobicContact CG2-CD1 4.49Å; T310-F532 WeakPolarHBondContact OG1-CD1 3.38Å; T310-F532 WeakPolarHBondContact OG1-CE1 3.26Å; T310-A533 HydrophobicContact CG2-CB 3.81Å
311L81.5Confident83.8Confident45 Ų4561.1 Ų61.124%0.23631%0.311CS..Hα-helixtrans-69.1-20.6177.5-69.5169.1000113.5A307 L308 G313 Y316 L317 V536 L540A307-L311 WeakPolarHBondContact O-CB 3.32Å; A307-L311 VanDerWaalsContact O-CG 3.24Å; A307-L311 WeakPolarHBondContact O-CG 3.46Å; A307-L311 PolarHBondContact O-N 3.35Å; L308-L311 PolarHBondContact O-N 3.4Å; L311-G313 PolarHBondContact O-N 2.86Å; L311-Y316 HydrophobicContact CD2-CE1 4.12Å; L311-L317 HydrophobicContact CD2-CD1 3.86Å; L311-V536 HydrophobicContact CD1-CG1 4.49Å; L311-V536 HydrophobicContact CD2-CG1 3.98Å; L311-V536 HydrophobicContact CG-CG1 4.21Å; L311-L540 HydrophobicContact CD2-CD1 3.85Å
312S82.6Confident84.7Confident87 Ų8752.6 Ų52.661%0.60827%0.274SS*.THydrogen-bonded Turntrans-71.3-12.8174.7-620000113L308 R309 T310 P314L308-S312 WeakPolarHBondContact O-CB 3.27Å; L308-S312 PolarHBondContact O-N 3.12Å; L308-S312 PolarHBondContact O-OG 3.06Å; R309-S312 WeakPolarHBondContact O-CB 3.42Å; R309-S312 PolarHBondContact O-N 2.96Å; T310-S312 PolarHBondContact O-N 3.29Å; S312-P314 WeakPolarHBondContact O-CD 3.39Å
313G86.2Confident85.8Confident25 Ų2551.2 Ų51.226%0.25826%0.264SS..  trans-72108172.800000111.7T310 L311 I315 Y316 L317T310-G313 PolarHBondContact O-N 3.44Å; L311-G313 PolarHBondContact O-N 2.86Å; G313-I315 PolarHBondContact O-N 2.87Å; G313-Y316 PolarHBondContact O-N 2.99Å; G313-L317 PolarHBondContact O-N 3.11Å
314P87.1Confident86.9Confident64 Ų6449.3 Ų49.342%0.41626%0.256SS..Hα-helixtrans-64.8-36.9-168.723.9-34.5000113.2S312 L318S312-P314 WeakPolarHBondContact O-CD 3.39Å; P314-L318 WeakPolarHBondContact O-CB 3.39Å; P314-L318 WeakPolarHBondContact O-CD1 3.27Å; P314-L318 WeakPolarHBondContact O-CG 3.36Å; P314-L318 PolarHBondContact O-N 2.97Å; P314-L318 VanDerWaalsContact O-N 3.1Å
315I91.2Very high87.8Confident6 Ų647.3 Ų47.33%0.03124%0.241CC..Hα-helixtrans-69.6-44.4178.4-66.4165.8000110.7G313 L318 V319 T524 T604 A607 L608G313-I315 PolarHBondContact O-N 2.87Å; I315-L318 PolarHBondContact O-N 3.27Å; I315-V319 HydrophobicContact CG2-CG2 4.47Å; I315-V319 VanDerWaalsContact O-CG2 3.24Å; I315-V319 WeakPolarHBondContact O-CG2 3.48Å; I315-V319 PolarHBondContact O-N 3.48Å; I315-V319 VanDerWaalsContact O-N 3.08Å; I315-T524 HydrophobicContact CG2-CG2 3.55Å; I315-T604 HydrophobicContact CG2-CG2 4.16Å; I315-A607 HydrophobicContact CG1-CB 4.03Å; I315-L608 HydrophobicContact CD1-CD2 3.66Å; I315-L608 HydrophobicContact CD1-CG 4.17Å; I315-L608 HydrophobicContact CG1-CD2 4.47Å; I315-L608 HydrophobicContact CG2-CD2 4.49Å
316Y91.8Very high88.6Confident7 Ų737.8 Ų37.83%0.02721%0.206CC..Hα-helixtrans-59.8-51.2177.8167.1-97.2000110.6T310 L311 G313 L318 V319 V320 V521 V525 A533 Q537T310-Y316 HydrophobicContact CG2-CD1 4.08Å; T310-Y316 HydrophobicContact CG2-CE1 3.7Å; T310-Y316 HydrophobicContact CG2-CE2 4.5Å; T310-Y316 VanDerWaalsContact O-CD1 3.3Å; T310-Y316 WeakPolarHBondContact O-CD1 3.44Å; L311-Y316 HydrophobicContact CD2-CE1 4.12Å; G313-Y316 PolarHBondContact O-N 2.99Å; Y316-L318 PolarHBondContact O-N 3.23Å; Y316-V319 PolarHBondContact O-N 3.31Å; Y316-V320 HydrophobicContact CD2-CG2 4.05Å; Y316-V320 HydrophobicContact CE1-CG2 4.12Å; Y316-V320 HydrophobicContact CE2-CG2 3.59Å; Y316-V320 HydrophobicContact CG-CG2 4.48Å; Y316-V320 WeakPolarHBondContact O-CB 3.44Å; Y316-V320 WeakPolarHBondContact O-CG2 3.06Å; Y316-V320 PolarHBondContact O-N 3.19Å; Y316-V521 HydrophobicContact CD2-CG1 3.87Å; Y316-V521 HydrophobicContact CE2-CG1 3.63Å; Y316-V525 HydrophobicContact CD2-CG2 3.67Å; Y316-V525 HydrophobicContact CE2-CG2 4.3Å; Y316-V525 HydrophobicContact CG-CG2 4.27Å; Y316-A533 HydrophobicContact CD2-CB 4.43Å; Y316-A533 HydrophobicContact CE2-CB 3.73Å; Y316-A533 PolarHBondContact OH-O 3.4Å; Y316-Q537 PolarHBondContact OH-N 2.85Å
317L93.8Very high89.7Confident59 Ų5935.7 Ų35.731%0.30920%0.197SC..Hα-helixtrans-59-46.9-179.7-178.763.9000112L311 G313 V319 V320 L321L311-L317 HydrophobicContact CD2-CD1 3.86Å; G313-L317 PolarHBondContact O-N 3.11Å; L317-V319 PolarHBondContact O-N 3.4Å; L317-V320 PolarHBondContact O-N 2.91Å; L317-L321 HydrophobicContact CD1-CD1 4.25Å; L317-L321 HydrophobicContact CD1-CG 4.24Å; L317-L321 HydrophobicContact CG-CD1 4.02Å; L317-L321 HydrophobicContact CG-CG 4.41Å; L317-L321 WeakPolarHBondContact O-CB 3.43Å; L317-L321 VanDerWaalsContact O-CG 3.3Å; L317-L321 WeakPolarHBondContact O-CG 3.32Å; L317-L321 PolarHBondContact O-N 3.46Å
318L95.4Very high90.7Very high33 Ų3335.4 Ų35.417%0.17319%0.194CC..Hα-helixtrans-61.8-42.9179.5-72.2168.9000112.3P314 I315 Y316 L321 A322 C600 L603 T604P314-L318 WeakPolarHBondContact O-CB 3.39Å; P314-L318 WeakPolarHBondContact O-CD1 3.27Å; P314-L318 WeakPolarHBondContact O-CG 3.36Å; P314-L318 PolarHBondContact O-N 2.97Å; P314-L318 VanDerWaalsContact O-N 3.1Å; I315-L318 PolarHBondContact O-N 3.27Å; Y316-L318 PolarHBondContact O-N 3.23Å; L318-L321 PolarHBondContact O-N 2.9Å; L318-A322 PolarHBondContact O-N 3.31Å; L318-C600 WeakPolarHBondContact O-CB 3.34Å; L318-L603 HydrophobicContact CD1-CB 3.89Å; L318-L603 HydrophobicContact CD2-CB 3.9Å; L318-L603 HydrophobicContact CD2-CD1 3.97Å; L318-T604 VanDerWaalsContact CB-OG1 3.29Å; L318-T604 WeakPolarHBondContact CB-OG1 3.34Å
319V95.3Very high91.5Very high0 Ų029.8 Ų29.80%017%0.165CC..Hα-helixtrans-66.9-40.8177.8176.50000111.1I315 Y316 L317 A322 L323 M520 V521 T604I315-V319 HydrophobicContact CG2-CG2 4.47Å; I315-V319 VanDerWaalsContact O-CG2 3.24Å; I315-V319 WeakPolarHBondContact O-CG2 3.48Å; I315-V319 PolarHBondContact O-N 3.48Å; I315-V319 VanDerWaalsContact O-N 3.08Å; Y316-V319 PolarHBondContact O-N 3.31Å; L317-V319 PolarHBondContact O-N 3.4Å; V319-A322 WeakPolarHBondContact O-CB 3.38Å; V319-A322 PolarHBondContact O-N 2.74Å; V319-L323 HydrophobicContact CG1-CD1 4.32Å; V319-L323 WeakPolarHBondContact O-CG 3.22Å; V319-L323 PolarHBondContact O-N 3.3Å; V319-M520 HydrophobicContact CG1-CB 4.25Å; V319-M520 HydrophobicContact CG2-CE 3.68Å; V319-V521 HydrophobicContact CB-CG2 4.38Å; V319-V521 HydrophobicContact CG1-CG2 3.69Å; V319-T604 HydrophobicContact CG2-CG2 3.76Å
320V95.3Very high92.3Very high0 Ų026 Ų260%016%0.158CC..Hα-helixtrans-65.5-40.8176.4172.60000111.3Y316 L317 A322 L323 V324 V521 Q537 L540Y316-V320 HydrophobicContact CD2-CG2 4.05Å; Y316-V320 HydrophobicContact CE1-CG2 4.12Å; Y316-V320 HydrophobicContact CE2-CG2 3.59Å; Y316-V320 HydrophobicContact CG-CG2 4.48Å; Y316-V320 WeakPolarHBondContact O-CB 3.44Å; Y316-V320 WeakPolarHBondContact O-CG2 3.06Å; Y316-V320 PolarHBondContact O-N 3.19Å; L317-V320 PolarHBondContact O-N 2.91Å; V320-A322 VanDerWaalsContact C-N 3.33Å; V320-A322 PolarHBondContact O-N 3.22Å; V320-L323 CarbonylContact O-C 3.51Å; V320-L323 WeakPolarHBondContact O-CB 3.32Å; V320-L323 PolarHBondContact O-N 2.97Å; V320-V324 HydrophobicContact CG1-CG2 4.38Å; V320-V324 VanDerWaalsContact O-CG2 3.31Å; V320-V324 WeakPolarHBondContact O-CG2 3.41Å; V320-V324 PolarHBondContact O-N 3.44Å; V320-V521 HydrophobicContact CG2-CG2 4.16Å; V320-Q537 HydrophobicContact CG1-CB 4.44Å; V320-Q537 HydrophobicContact CG1-CG 4.2Å; V320-Q537 HydrophobicContact CG2-CB 4.21Å; V320-Q537 HydrophobicContact CG2-CG 4.1Å; V320-L540 HydrophobicContact CG1-CB 4.34Å; V320-L540 HydrophobicContact CG1-CD1 3.61Å
321L96Very high93.1Very high57 Ų5725.7 Ų25.730%0.29816%0.157SC..Hα-helixtrans-63.8-37174.1-72.9173.9000112.3L317 L318 L323 V324 N325L317-L321 HydrophobicContact CD1-CD1 4.25Å; L317-L321 HydrophobicContact CD1-CG 4.24Å; L317-L321 HydrophobicContact CG-CD1 4.02Å; L317-L321 HydrophobicContact CG-CG 4.41Å; L317-L321 WeakPolarHBondContact O-CB 3.43Å; L317-L321 VanDerWaalsContact O-CG 3.3Å; L317-L321 WeakPolarHBondContact O-CG 3.32Å; L317-L321 PolarHBondContact O-N 3.46Å; L318-L321 PolarHBondContact O-N 2.9Å; L321-L323 VanDerWaalsContact C-N 3.34Å; L321-V324 PolarHBondContact O-N 3.24Å; L321-N325 PolarHBondContact O-N 3Å; L321-N325 PolarHBondContact O-ND2 3.49Å
322A96.9Very high93.8Very high0 Ų023.6 Ų23.60%015%0.146CC..Hα-helixtrans-60.5-46.8172.200000110.9L318 V319 V320 V324 N325 M326 C600 F601L318-A322 PolarHBondContact O-N 3.31Å; V319-A322 WeakPolarHBondContact O-CB 3.38Å; V319-A322 PolarHBondContact O-N 2.74Å; V320-A322 VanDerWaalsContact C-N 3.33Å; V320-A322 PolarHBondContact O-N 3.22Å; A322-V324 PolarHBondContact O-N 3.48Å; A322-N325 PolarHBondContact O-N 3.21Å; A322-M326 VanDerWaalsContact O-CG 3.32Å; A322-M326 WeakPolarHBondContact O-CG 3.37Å; A322-M326 PolarHBondContact O-N 3.46Å; A322-M326 VanDerWaalsContact O-N 3.12Å; A322-C600 HydrophobicContact CB-CB 3.58Å; A322-F601 HydrophobicContact CB-CD1 4.29Å; A322-F601 HydrophobicContact CB-CD2 4.11Å; A322-F601 HydrophobicContact CB-CE1 3.98Å; A322-F601 HydrophobicContact CB-CE2 3.8Å; A322-F601 HydrophobicContact CB-CG 4.33Å; A322-F601 HydrophobicContact CB-CZ 3.71Å
323L95.6Very high94.4Very high9 Ų920.5 Ų20.55%0.04712%0.123CC..Hα-helixtrans-65.1-35.4177.1-76.7168.4000113V319 V320 L321 M326 A327 V521 F541V319-L323 HydrophobicContact CG1-CD1 4.32Å; V319-L323 WeakPolarHBondContact O-CG 3.22Å; V319-L323 PolarHBondContact O-N 3.3Å; V320-L323 CarbonylContact O-C 3.51Å; V320-L323 WeakPolarHBondContact O-CB 3.32Å; V320-L323 PolarHBondContact O-N 2.97Å; L321-L323 VanDerWaalsContact C-N 3.34Å; L323-M326 PolarHBondContact O-N 2.89Å; L323-A327 VanDerWaalsContact O-CB 3.29Å; L323-A327 WeakPolarHBondContact O-CB 3.37Å; L323-A327 PolarHBondContact O-N 3.22Å; L323-V521 HydrophobicContact CD1-CG2 4.18Å; L323-F541 HydrophobicContact CB-CE1 3.51Å; L323-F541 HydrophobicContact CB-CZ 3.56Å; L323-F541 HydrophobicContact CD1-CZ 4.19Å; L323-F541 HydrophobicContact CG-CZ 4.31Å
324V97.2Very high94.7Very high9 Ų920 Ų206%0.05512%0.116CC..Hα-helixtrans-61.7-46.2173.6165.60000110.5V320 L321 A322 M326 A327 A328 L540 F541 L544 A545V320-V324 HydrophobicContact CG1-CG2 4.38Å; V320-V324 VanDerWaalsContact O-CG2 3.31Å; V320-V324 WeakPolarHBondContact O-CG2 3.41Å; V320-V324 PolarHBondContact O-N 3.44Å; L321-V324 PolarHBondContact O-N 3.24Å; A322-V324 PolarHBondContact O-N 3.48Å; V324-M326 VanDerWaalsContact C-N 3.31Å; V324-M326 PolarHBondContact O-N 3.03Å; V324-A327 PolarHBondContact O-N 2.98Å; V324-A328 WeakPolarHBondContact O-CB 3.41Å; V324-A328 PolarHBondContact O-N 3.34Å; V324-L540 HydrophobicContact CG2-CB 4.19Å; V324-F541 HydrophobicContact CG2-CD1 3.81Å; V324-F541 HydrophobicContact CG2-CE1 4.18Å; V324-L544 HydrophobicContact CG1-CB 3.6Å; V324-L544 HydrophobicContact CG1-CD1 4.46Å; V324-A545 HydrophobicContact CG1-CB 4.19Å; V324-A545 WeakPolarHBondContact O-CB 3.35Å
325N97.1Very high95.1Very high36 Ų3617 Ų1719%0.19310%0.097CC..Hα-helixtrans-58.7-44.6175.8-82.1-86.7000111.6L321 A322 A328 L329 F593 A597L321-N325 PolarHBondContact O-N 3Å; L321-N325 PolarHBondContact O-ND2 3.49Å; A322-N325 PolarHBondContact O-N 3.21Å; N325-A328 PolarHBondContact O-N 2.68Å; N325-L329 WeakPolarHBondContact O-CB 3.46Å; N325-L329 PolarHBondContact O-N 3.08Å; N325-F593 HydrophobicContact CB-CD1 4.45Å; N325-F593 WeakPolarHBondContact CB-O 3.01Å; N325-A597 HydrophobicContact CB-CB 4.08Å
326M95.6Very high95.4Very high12 Ų1216.8 Ų16.86%0.05910%0.095CC..Hα-helixtrans-66-39.4177.8-64-65.6-77.800112.3A322 L323 V324 L329 V330 I393 I510 A597A322-M326 VanDerWaalsContact O-CG 3.32Å; A322-M326 WeakPolarHBondContact O-CG 3.37Å; A322-M326 PolarHBondContact O-N 3.46Å; A322-M326 VanDerWaalsContact O-N 3.12Å; L323-M326 PolarHBondContact O-N 2.89Å; V324-M326 VanDerWaalsContact C-N 3.31Å; V324-M326 PolarHBondContact O-N 3.03Å; M326-L329 WeakPolarHBondContact O-CB 3.42Å; M326-V330 VanDerWaalsContact O-CG2 3.31Å; M326-V330 WeakPolarHBondContact O-CG2 3.46Å; M326-V330 PolarHBondContact O-N 3.13Å; M326-I393 HydrophobicContact CE-CD1 3.45Å; M326-I393 VanDerWaalsContact CE-CD1 3.45Å; M326-I393 HydrophobicContact SD-CD1 3.66Å; M326-I510 HydrophobicContact CE-CB 3.79Å; M326-I510 HydrophobicContact CE-CG1 3.84Å; M326-I510 HydrophobicContact CE-CG2 3.4Å; M326-I510 VanDerWaalsContact CE-CG2 3.4Å; M326-A597 HydrophobicContact CG-CB 3.89Å; M326-A597 HydrophobicContact SD-CB 3.83Å
327A95.1Very high95.6Very high12 Ų1216.6 Ų16.610%0.09910%0.095CC..Hα-helixtrans-67.1-39.417600000111.8L323 V324 V330 S331 F541 A545 F546L323-A327 VanDerWaalsContact O-CB 3.29Å; L323-A327 WeakPolarHBondContact O-CB 3.37Å; L323-A327 PolarHBondContact O-N 3.22Å; V324-A327 PolarHBondContact O-N 2.98Å; A327-V330 PolarHBondContact O-N 3.29Å; A327-S331 VanDerWaalsContact O-CB 3.29Å; A327-S331 WeakPolarHBondContact O-CB 3.42Å; A327-S331 PolarHBondContact O-N 2.82Å; A327-F541 HydrophobicContact CB-CD1 4.46Å; A327-F541 HydrophobicContact CB-CG 4.41Å; A327-A545 HydrophobicContact CB-CB 3.7Å; A327-F546 HydrophobicContact CB-CE1 4.04Å; A327-F546 HydrophobicContact CB-CZ 4.2Å
328A96.9Very high95.7Very high2 Ų214.1 Ų14.12%0.0178%0.082CC..Hα-helixtrans-64.4-43.817800000110.8V324 N325 S331 G332 A545 F593V324-A328 WeakPolarHBondContact O-CB 3.41Å; V324-A328 PolarHBondContact O-N 3.34Å; N325-A328 PolarHBondContact O-N 2.68Å; A328-S331 PolarHBondContact O-N 3.3Å; A328-G332 PolarHBondContact O-N 3.17Å; A328-A545 HydrophobicContact CB-CB 3.8Å; A328-F593 HydrophobicContact CB-CD1 4.01Å; A328-F593 HydrophobicContact CB-CE1 3.62Å; A328-F593 HydrophobicContact CB-CE2 4.35Å; A328-F593 HydrophobicContact CB-CZ 3.81Å
329L95.9Very high95.8Very high0 Ų013 Ų130%08%0.076CC..Hα-helixtrans-54.7-57.4171.2171.366000111.5N325 M326 S331 G332 L333 I510 M590 F593 V594N325-L329 WeakPolarHBondContact O-CB 3.46Å; N325-L329 PolarHBondContact O-N 3.08Å; M326-L329 WeakPolarHBondContact O-CB 3.42Å; L329-S331 VanDerWaalsContact C-N 3.3Å; L329-S331 PolarHBondContact O-N 3.22Å; L329-G332 PolarHBondContact O-N 3.36Å; L329-L333 HydrophobicContact CD1-CD1 3.68Å; L329-L333 HydrophobicContact CD1-CG 3.94Å; L329-L333 HydrophobicContact CG-CD1 4.2Å; L329-L333 WeakPolarHBondContact O-CB 3.48Å; L329-L333 WeakPolarHBondContact O-CG 3.41Å; L329-L333 PolarHBondContact O-N 3.21Å; L329-I510 HydrophobicContact CD2-CD1 3.6Å; L329-I510 HydrophobicContact CD2-CG1 4.36Å; L329-M590 HydrophobicContact CD1-CB 3.55Å; L329-M590 HydrophobicContact CD1-CG 3.53Å; L329-M590 HydrophobicContact CD1-SD 4.39Å; L329-F593 HydrophobicContact CB-CB 3.94Å; L329-F593 HydrophobicContact CB-CD2 4.33Å; L329-F593 HydrophobicContact CB-CG 4.34Å; L329-V594 HydrophobicContact CD2-CG2 3.74Å
330V93.8Very high95.8Very high71 Ų7113 Ų1343%0.438%0.076SC..Hα-helixtrans-61.4-39.8-177.7171.50000111.3M326 A327 A334 I510M326-V330 VanDerWaalsContact O-CG2 3.31Å; M326-V330 WeakPolarHBondContact O-CG2 3.46Å; M326-V330 PolarHBondContact O-N 3.13Å; A327-V330 PolarHBondContact O-N 3.29Å; V330-A334 WeakPolarHBondContact O-CB 3.28Å; V330-A334 PolarHBondContact O-N 3.4Å; V330-I510 HydrophobicContact CG2-CG2 3.93Å
331S94.6Very high95.8Very high6 Ų613 Ų134%0.0428%0.076CC..Hα-helixtrans-61.3-49178-164.20000112.5A327 A328 L329 T335 P550A327-S331 VanDerWaalsContact O-CB 3.29Å; A327-S331 WeakPolarHBondContact O-CB 3.42Å; A327-S331 PolarHBondContact O-N 2.82Å; A328-S331 PolarHBondContact O-N 3.3Å; L329-S331 VanDerWaalsContact C-N 3.3Å; L329-S331 PolarHBondContact O-N 3.22Å; S331-T335 WeakPolarHBondContact O-CB 3.49Å; S331-T335 PolarHBondContact O-N 2.99Å; S331-T335 VanDerWaalsContact O-N 3.13Å; S331-T335 PolarHBondContact O-OG1 3.35Å; S331-P550 WeakPolarHBondContact OG-CD 3.2Å; S331-P550 WeakPolarHBondContact OG-CG 3.43Å
332G95.6Very high95.7Very high0 Ų010.6 Ų10.60%06%0.063CC..Hα-helixtrans-65.5-46.5-179.900000112.8A328 L329 T335 F336A328-G332 PolarHBondContact O-N 3.17Å; L329-G332 PolarHBondContact O-N 3.36Å; G332-T335 PolarHBondContact O-N 3.02Å; G332-F336 PolarHBondContact O-N 3.42Å
333L95.3Very high95.4Very high23 Ų2312.1 Ų12.112%0.127%0.07CC..Hα-helixtrans-64.7-45.1177.1-65.7-171000111.8L329 T335 F336 M337 Y553 F586 M590L329-L333 HydrophobicContact CD1-CD1 3.68Å; L329-L333 HydrophobicContact CD1-CG 3.94Å; L329-L333 HydrophobicContact CG-CD1 4.2Å; L329-L333 WeakPolarHBondContact O-CB 3.48Å; L329-L333 WeakPolarHBondContact O-CG 3.41Å; L329-L333 PolarHBondContact O-N 3.21Å; L333-T335 PolarHBondContact O-N 3.35Å; L333-F336 PolarHBondContact O-N 3.01Å; L333-M337 HydrophobicContact CB-CE 4.39Å; L333-M337 HydrophobicContact CD1-CE 4.05Å; L333-M337 HydrophobicContact CD2-CE 3.65Å; L333-M337 HydrophobicContact CG-CE 4.23Å; L333-M337 WeakPolarHBondContact O-CA 3.42Å; L333-M337 WeakPolarHBondContact O-CB 3.32Å; L333-M337 PolarHBondContact O-N 3.21Å; L333-Y553 HydrophobicContact CD2-CE1 3.86Å; L333-F586 HydrophobicContact CD2-CE1 3.7Å; L333-F586 HydrophobicContact CD2-CZ 3.97Å; L333-M590 HydrophobicContact CD1-CE 4.28Å; L333-M590 HydrophobicContact CD1-SD 3.91Å
334A93.1Very high95.3Very high14 Ų1411.7 Ų11.712%0.1167%0.067CC..Hα-helixtrans-58.7-33.1176.600000111.8K44 F208 V330K44-A334 HydrophobicContact CD-CB 4.46Å; F208-A334 VanDerWaalsContact CZ-O 3.23Å; F208-A334 WeakPolarHBondContact CZ-O 3.07Å; V330-A334 WeakPolarHBondContact O-CB 3.28Å; V330-A334 PolarHBondContact O-N 3.4Å
335T96.1Very high95.1Very high2 Ų211.2 Ų11.21%0.0127%0.065CC..Hα-helixtrans-78.5-44.1-178.1-53.80000112.6I47 A65 S331 G332 L333 P550I47-T335 HydrophobicContact CD1-CG2 3.22Å; A65-T335 HydrophobicContact CB-CG2 3.69Å; S331-T335 WeakPolarHBondContact O-CB 3.49Å; S331-T335 PolarHBondContact O-N 2.99Å; S331-T335 VanDerWaalsContact O-N 3.13Å; S331-T335 PolarHBondContact O-OG1 3.35Å; G332-T335 PolarHBondContact O-N 3.02Å; L333-T335 PolarHBondContact O-N 3.35Å; T335-P550 HydrophobicContact CG2-CB 4.15Å
336F97.5Very high94.8Very high0 Ų011 Ų110%07%0.066CC..Hα-helixtrans-117.9-5.3-168.8-71.6-71000115.6I47 S58 G332 L333 P338 K339 F340 P550 I557 F586I47-F336 HydrophobicContact CG2-CE1 3.9Å; S58-F336 WeakPolarHBondContact O-CZ 3.47Å; G332-F336 PolarHBondContact O-N 3.42Å; L333-F336 PolarHBondContact O-N 3.01Å; F336-P338 VanDerWaalsContact C-CD 3.48Å; F336-K339 HydrophobicContact CD1-CD 4.15Å; F336-K339 WeakPolarHBondContact O-CB 3.22Å; F336-K339 PolarHBondContact O-N 2.81Å; F336-F340 PolarHBondContact O-N 3.14Å; F336-P550 HydrophobicContact CE2-CB 4.44Å; F336-P550 WeakPolarHBondContact CE2-O 3.21Å; F336-I557 HydrophobicContact CB-CD1 3.68Å; F336-I557 HydrophobicContact CD1-CD1 3.45Å; F336-I557 VanDerWaalsContact CD1-CD1 3.45Å; F336-I557 HydrophobicContact CD2-CD1 4.17Å; F336-I557 HydrophobicContact CE1-CD1 4.11Å; F336-I557 HydrophobicContact CG-CD1 3.49Å; F336-I557 VanDerWaalsContact CG-CD1 3.49Å; F336-F586 HydrophobicContact CB-CE2 3.69Å; F336-F586 HydrophobicContact CB-CZ 4.03Å
337M96.3Very high94.6Very high4 Ų412.5 Ų12.52%0.027%0.073CC..Hα-helixtrans-60.7-38.1176-167.967.488.100113.4L333 K339 F340 I341 I356 F499 M503 F586L333-M337 HydrophobicContact CB-CE 4.39Å; L333-M337 HydrophobicContact CD1-CE 4.05Å; L333-M337 HydrophobicContact CD2-CE 3.65Å; L333-M337 HydrophobicContact CG-CE 4.23Å; L333-M337 WeakPolarHBondContact O-CA 3.42Å; L333-M337 WeakPolarHBondContact O-CB 3.32Å; L333-M337 PolarHBondContact O-N 3.21Å; M337-K339 VanDerWaalsContact C-N 3.33Å; M337-K339 PolarHBondContact O-N 2.95Å; M337-F340 WeakPolarHBondContact O-CB 2.94Å; M337-F340 PolarHBondContact O-N 3.45Å; M337-F340 VanDerWaalsContact O-N 3.16Å; M337-F340 HydrophobicContact SD-CB 4.12Å; M337-F340 HydrophobicContact SD-CD1 3.82Å; M337-F340 HydrophobicContact SD-CG 4.2Å; M337-I341 HydrophobicContact CG-CD1 4.06Å; M337-I341 HydrophobicContact CG-CG1 4.35Å; M337-I341 WeakPolarHBondContact O-CG1 3.48Å; M337-I341 PolarHBondContact O-N 2.78Å; M337-I356 HydrophobicContact CB-CD1 3.99Å; M337-I356 HydrophobicContact CG-CD1 3.62Å; M337-F499 HydrophobicContact SD-CZ 4.41Å; M337-M503 HydrophobicContact CE-CG 4.22Å; M337-M503 HydrophobicContact CE-SD 3.98Å; M337-M503 HydrophobicContact CG-CE 4.41Å; M337-M503 HydrophobicContact CG-SD 3.82Å; M337-M503 HydrophobicContact SD-SD 4.18Å; M337-F586 HydrophobicContact CE-CE1 4.3Å; M337-F586 HydrophobicContact SD-CE1 4.01Å
338P95.9Very high94.5Very high6 Ų613.5 Ų13.54%0.0398%0.078CC..Hα-helixtrans-57.2-46.7173.1-19.827.4000112.1F208 F336 F340 I341 E342 S352 N353 I356F208-P338 HydrophobicContact CD1-CG 4.35Å; F208-P338 HydrophobicContact CE1-CG 3.68Å; F336-P338 VanDerWaalsContact C-CD 3.48Å; P338-F340 VanDerWaalsContact C-N 3.32Å; P338-F340 PolarHBondContact O-N 3.23Å; P338-I341 PolarHBondContact O-N 2.86Å; P338-E342 VanDerWaalsContact O-CB 3.27Å; P338-E342 WeakPolarHBondContact O-CB 3.37Å; P338-E342 PolarHBondContact O-N 3.29Å; P338-S352 WeakPolarHBondContact O-CB 3.5Å; P338-N353 WeakPolarHBondContact CB-OD1 3.22Å; P338-I356 HydrophobicContact CG-CG1 3.9Å
339K95.9Very high94.3Very high9 Ų913.6 Ų13.64%0.0398%0.078CC..Hα-helixtrans-62.2-38.8175.7-178.7176.2-179.31720111.9E51 S58 F336 M337 K343 Y577E51-K339 IonicContact OE1-NZ 2.82Å; E51-K339 WeakPolarHBondContact OE2-CE 3.43Å; E51-K339 IonicContact OE2-NZ 3.79Å; E51-K339 PolarHBondContact OE2-NZ 3.07Å; S58-K339 PolarHBondContact OG-NZ 3.07Å; F336-K339 HydrophobicContact CD1-CD 4.15Å; F336-K339 WeakPolarHBondContact O-CB 3.22Å; F336-K339 PolarHBondContact O-N 2.81Å; M337-K339 VanDerWaalsContact C-N 3.33Å; M337-K339 PolarHBondContact O-N 2.95Å; K339-K343 WeakPolarHBondContact O-CG 3.13Å; K339-K343 PolarHBondContact O-N 2.88Å; K339-Y577 VanDerWaalsContact CE-OH 3.3Å; K339-Y577 WeakPolarHBondContact CE-OH 3.5Å; K339-Y577 PolarHBondContact NZ-OH 3.26Å
340F96.1Very high94.3Very high0 Ų013.8 Ų13.80%08%0.079CC..Hα-helixtrans-59.6-51.4174.3-178.9-92.8000111F336 M337 P338 E342 K343 Q344 F345 F499 F582 R583 F586 L587F336-F340 PolarHBondContact O-N 3.14Å; M337-F340 WeakPolarHBondContact O-CB 2.94Å; M337-F340 PolarHBondContact O-N 3.45Å; M337-F340 VanDerWaalsContact O-N 3.16Å; M337-F340 HydrophobicContact SD-CB 4.12Å; M337-F340 HydrophobicContact SD-CD1 3.82Å; M337-F340 HydrophobicContact SD-CG 4.2Å; P338-F340 VanDerWaalsContact C-N 3.32Å; P338-F340 PolarHBondContact O-N 3.23Å; F340-E342 PolarHBondContact O-N 2.99Å; F340-K343 PolarHBondContact O-N 2.99Å; F340-Q344 HydrophobicContact CD1-CB 4.27Å; F340-Q344 HydrophobicContact CE1-CB 3.94Å; F340-Q344 HydrophobicContact CE1-CG 3.91Å; F340-Q344 HydrophobicContact CE2-CB 4.32Å; F340-Q344 HydrophobicContact CE2-CG 4.33Å; F340-Q344 HydrophobicContact CZ-CB 3.98Å; F340-Q344 HydrophobicContact CZ-CG 3.7Å; F340-Q344 WeakPolarHBondContact O-CA 3.39Å; F340-Q344 WeakPolarHBondContact O-CB 3.3Å; F340-Q344 PolarHBondContact O-N 2.98Å; F340-F345 HydrophobicContact CE1-CE2 4.45Å; F340-F499 HydrophobicContact CD1-CE1 4.4Å; F340-F499 AromaticContact CD1-CZ 3.96Å; F340-F499 HydrophobicContact CD1-CZ 3.96Å; F340-F499 HydrophobicContact CE1-CE1 4.18Å; F340-F499 AromaticContact CE1-CE2 3.86Å; F340-F499 HydrophobicContact CE1-CE2 3.86Å; F340-F499 AromaticContact CE1-CZ 3.44Å; F340-F499 HydrophobicContact CE1-CZ 3.44Å; F340-F499 VanDerWaalsContact CE1-CZ 3.44Å; F340-F499 HydrophobicContact CZ-CZ 4.48Å; F340-F582 HydrophobicContact CB-CZ 4.33Å; F340-F582 HydrophobicContact CD2-CD2 4.23Å; F340-F582 HydrophobicContact CD2-CE1 4.28Å; F340-F582 AromaticContact CD2-CE2 3.72Å; F340-F582 HydrophobicContact CD2-CE2 3.72Å; F340-F582 AromaticContact CD2-CZ 3.78Å; F340-F582 HydrophobicContact CD2-CZ 3.78Å; F340-F582 HydrophobicContact CE2-CD2 4.44Å; F340-F582 HydrophobicContact CE2-CE2 4.36Å; F340-R583 HydrophobicContact CE2-CB 4.39Å; F340-R583 HydrophobicContact CZ-CB 4.27Å; F340-R583 HydrophobicContact CZ-CG 4.15Å; F340-F586 HydrophobicContact CB-CD1 4.36Å; F340-F586 HydrophobicContact CB-CE1 3.94Å; F340-F586 HydrophobicContact CB-CZ 4.11Å; F340-F586 HydrophobicContact CD2-CB 4.17Å; F340-F586 AromaticContact CD2-CD1 3.48Å; F340-F586 HydrophobicContact CD2-CD1 3.48Å; F340-F586 VanDerWaalsContact CD2-CD1 3.48Å; F340-F586 HydrophobicContact CD2-CD2 4.48Å; F340-F586 AromaticContact CD2-CE1 3.94Å; F340-F586 HydrophobicContact CD2-CE1 3.94Å; F340-F586 AromaticContact CD2-CG 3.81Å; F340-F586 HydrophobicContact CD2-CG 3.81Å; F340-F586 HydrophobicContact CE2-CB 4.2Å; F340-F586 AromaticContact CE2-CD1 3.92Å; F340-F586 HydrophobicContact CE2-CD1 3.92Å; F340-F586 HydrophobicContact CE2-CG 4.26Å; F340-F586 AromaticContact CG-CD1 3.92Å; F340-F586 HydrophobicContact CG-CD1 3.92Å; F340-F586 AromaticContact CG-CE1 3.9Å; F340-F586 HydrophobicContact CG-CE1 3.9Å; F340-L587 HydrophobicContact CE1-CD1 4.45Å; F340-L587 HydrophobicContact CE2-CG 4.49Å; F340-L587 HydrophobicContact CZ-CD1 3.97Å; F340-L587 HydrophobicContact CZ-CG 4.13Å
341I95.2Very high94.3Very high0 Ų013.8 Ų13.80%08%0.076CC..Hα-helixtrans-63.3-44.1179.7-64.8167.2000110.9M337 P338 K343 F345 Q347 S352 M355 I356 L496 F499 I500 M503M337-I341 HydrophobicContact CG-CD1 4.06Å; M337-I341 HydrophobicContact CG-CG1 4.35Å; M337-I341 WeakPolarHBondContact O-CG1 3.48Å; M337-I341 PolarHBondContact O-N 2.78Å; P338-I341 PolarHBondContact O-N 2.86Å; I341-K343 VanDerWaalsContact C-N 3.33Å; I341-K343 PolarHBondContact O-N 3.2Å; I341-F345 PolarHBondContact O-N 3.39Å; I341-F345 VanDerWaalsContact O-N 3.17Å; I341-Q347 HydrophobicContact CG2-CB 4.41Å; I341-Q347 HydrophobicContact CG2-CG 4.35Å; I341-S352 WeakPolarHBondContact CG2-OG 3.45Å; I341-M355 HydrophobicContact CD1-CB 4.46Å; I341-M355 HydrophobicContact CG2-SD 3.98Å; I341-I356 HydrophobicContact CD1-CD1 3.77Å; I341-L496 HydrophobicContact CG2-CD1 4.07Å; I341-F499 HydrophobicContact CG1-CE1 4.32Å; I341-I500 HydrophobicContact CD1-CD1 3.93Å; I341-M503 HydrophobicContact CD1-SD 4.41Å
342E93.1Very high94.3Very high8 Ų813.5 Ų13.54%0.0377%0.074CC..Hα-helixtrans-52.6-49.5176.9-177.7-157.612500111.2S48 R52 P338 F340 S346 Q347 I349 S352S48-E342 WeakPolarHBondContact CB-OE2 3.34Å; S48-E342 PolarHBondContact OG-OE2 3.29Å; R52-E342 IonicContact CZ-OE1 3.45Å; R52-E342 IonicContact NE-OE1 3.01Å; R52-E342 IonicContact NH2-OE1 2.78Å; R52-E342 PolarHBondContact NH2-OE1 3.16Å; P338-E342 VanDerWaalsContact O-CB 3.27Å; P338-E342 WeakPolarHBondContact O-CB 3.37Å; P338-E342 PolarHBondContact O-N 3.29Å; F340-E342 PolarHBondContact O-N 2.99Å; E342-S346 CarbonylContact O-C 3.47Å; E342-S346 VanDerWaalsContact O-CA 3.32Å; E342-S346 WeakPolarHBondContact O-CA 3.41Å; E342-S346 PolarHBondContact O-N 3.19Å; E342-Q347 WeakPolarHBondContact CG-O 3.23Å; E342-Q347 PolarHBondContact O-N 3.05Å; E342-Q347 VanDerWaalsContact O-N 3.08Å; E342-I349 HydrophobicContact CG-CG1 4.17Å; E342-I349 WeakPolarHBondContact OE2-CG1 3.09Å; E342-S352 PolarHBondContact N-OG 3.37Å
343K92.3Very high94.4Very high31 Ų3113.5 Ų13.514%0.1357%0.074CC..Hα-helixtrans-84.4-41.4-176.7-62.6-58-176.5-179.30113.8K339 F340 I341 F345 Y577 F582K339-K343 WeakPolarHBondContact O-CG 3.13Å; K339-K343 PolarHBondContact O-N 2.88Å; F340-K343 PolarHBondContact O-N 2.99Å; I341-K343 VanDerWaalsContact C-N 3.33Å; I341-K343 PolarHBondContact O-N 3.2Å; K343-F345 VanDerWaalsContact C-N 3.32Å; K343-F345 PolarHBondContact O-N 3.39Å; K343-Y577 HydrophobicContact CD-CD2 4.47Å; K343-Y577 HydrophobicContact CG-CD2 4.36Å; K343-Y577 HydrophobicContact CG-CE2 4.45Å; K343-F582 HydrophobicContact CB-CE1 4Å
344Q93.5Very high94.4Very high0 Ų015.9 Ų15.90%09%0.085CC..Hα-helixtrans-72.4-25.5-173.8-171.559.34600113.1F340 C408 L579F340-Q344 HydrophobicContact CD1-CB 4.27Å; F340-Q344 HydrophobicContact CE1-CB 3.94Å; F340-Q344 HydrophobicContact CE1-CG 3.91Å; F340-Q344 HydrophobicContact CE2-CB 4.32Å; F340-Q344 HydrophobicContact CE2-CG 4.33Å; F340-Q344 HydrophobicContact CZ-CB 3.98Å; F340-Q344 HydrophobicContact CZ-CG 3.7Å; F340-Q344 WeakPolarHBondContact O-CA 3.39Å; F340-Q344 WeakPolarHBondContact O-CB 3.3Å; F340-Q344 PolarHBondContact O-N 2.98Å; Q344-C408 PolarHBondContact NE2-O 2.88Å; Q344-C408 WeakPolarHBondContact O-CB 3.37Å; Q344-C408 PolarHBondContact O-SG 3.02Å; Q344-L579 PolarHBondContact OE1-O 2.92Å
345F92.2Very high94.4Very high0 Ų016.4 Ų16.40%09%0.086CC..THydrogen-bonded Turntrans-125.612.2-177.4-62.4-81.6000113.3F340 I341 K343 Q347 L495 L496 F499F340-F345 HydrophobicContact CE1-CE2 4.45Å; I341-F345 PolarHBondContact O-N 3.39Å; I341-F345 VanDerWaalsContact O-N 3.17Å; K343-F345 VanDerWaalsContact C-N 3.32Å; K343-F345 PolarHBondContact O-N 3.39Å; F345-Q347 VanDerWaalsContact C-N 3.26Å; F345-Q347 HydrophobicContact CB-CG 3.89Å; F345-Q347 PolarHBondContact O-N 3.33Å; F345-Q347 PolarHBondContact O-NE2 3Å; F345-L495 HydrophobicContact CE1-CB 4.01Å; F345-L496 HydrophobicContact CB-CD1 3.97Å; F345-L496 HydrophobicContact CD1-CB 3.95Å; F345-L496 HydrophobicContact CD1-CD1 4.18Å; F345-L496 HydrophobicContact CD2-CD1 3.78Å; F345-L496 HydrophobicContact CE1-CB 4.4Å; F345-L496 HydrophobicContact CE2-CD1 4.31Å; F345-L496 HydrophobicContact CG-CB 4.29Å; F345-L496 HydrophobicContact CG-CD1 3.72Å; F345-F499 HydrophobicContact CE1-CB 4.4Å; F345-F499 HydrophobicContact CE2-CB 4.2Å; F345-F499 AromaticContact CE2-CD1 3.72Å; F345-F499 HydrophobicContact CE2-CD1 3.72Å; F345-F499 HydrophobicContact CE2-CD2 4.11Å; F345-F499 HydrophobicContact CE2-CE1 4.11Å; F345-F499 HydrophobicContact CE2-CE2 4.46Å; F345-F499 AromaticContact CE2-CG 3.73Å; F345-F499 HydrophobicContact CE2-CG 3.73Å; F345-F499 HydrophobicContact CE2-CZ 4.48Å; F345-F499 HydrophobicContact CZ-CB 3.65Å; F345-F499 HydrophobicContact CZ-CD1 4.04Å; F345-F499 AromaticContact CZ-CD2 3.86Å; F345-F499 HydrophobicContact CZ-CD2 3.86Å; F345-F499 AromaticContact CZ-CG 3.57Å; F345-F499 HydrophobicContact CZ-CG 3.57Å
346S90.4Very high94.3Very high31 Ų3116.7 Ų16.722%0.2179%0.087CC..THydrogen-bonded Turntrans51.942.4-180-49.30000113.3E342 S490E342-S346 CarbonylContact O-C 3.47Å; E342-S346 VanDerWaalsContact O-CA 3.32Å; E342-S346 WeakPolarHBondContact O-CA 3.41Å; E342-S346 PolarHBondContact O-N 3.19Å; S346-S490 WeakPolarHBondContact OG-CB 3.45Å; S346-S490 PolarHBondContact OG-OG 2.81Å; S346-S490 VanDerWaalsContact OG-OG 3.08Å
347Q91.6Very high94.1Very high44 Ų4416.9 Ų16.921%0.2069%0.089CC..  trans-96.4158.6-178.4-61.5-55.4-47.600111.5I341 E342 F345 L496I341-Q347 HydrophobicContact CG2-CB 4.41Å; I341-Q347 HydrophobicContact CG2-CG 4.35Å; E342-Q347 WeakPolarHBondContact CG-O 3.23Å; E342-Q347 PolarHBondContact O-N 3.05Å; E342-Q347 VanDerWaalsContact O-N 3.08Å; F345-Q347 VanDerWaalsContact C-N 3.26Å; F345-Q347 HydrophobicContact CB-CG 3.89Å; F345-Q347 PolarHBondContact O-N 3.33Å; F345-Q347 PolarHBondContact O-NE2 3Å; Q347-L496 HydrophobicContact CG-CD2 3.77Å
348T93.1Very high93.8Very high33 Ų3318.4 Ų18.420%0.20211%0.106CC..  trans-75.1149.9177.868.50000111.3Q233 K234 P350 L351 S352Q233-T348 HydrophobicContact CB-CG2 4.33Å; K234-T348 HydrophobicContact CB-CG2 4.47Å; T348-P350 VanDerWaalsContact C-N 3.34Å; T348-L351 PolarHBondContact O-N 3.47Å; T348-L351 VanDerWaalsContact O-N 3.08Å; T348-L351 WeakPolarHBondContact OG1-CB 3.48Å; T348-L351 PolarHBondContact OG1-N 3.38Å; T348-S352 PolarHBondContact O-N 3.48Å; T348-S352 PolarHBondContact O-OG 3.46Å
349I92.6Very high93.6Very high4 Ų421.9 Ų21.92%0.02112%0.124CC..Hα-helixtrans-52.5-46.4176.5-62.7160.4000111.6M215 E342 L351 N353M215-I349 HydrophobicContact CB-CG2 4.01Å; M215-I349 HydrophobicContact CG-CG2 4Å; E342-I349 HydrophobicContact CG-CG1 4.17Å; E342-I349 WeakPolarHBondContact OE2-CG1 3.09Å; I349-L351 PolarHBondContact O-N 3.13Å; I349-N353 WeakPolarHBondContact O-CB 3.15Å; I349-N353 PolarHBondContact O-N 3.14Å; I349-N353 VanDerWaalsContact O-N 3.1Å; I349-N353 PolarHBondContact O-ND2 3.24Å
350P95.3Very high93.3Very high4 Ų421.7 Ų21.73%0.02612%0.124CC..Hα-helixtrans-53.6-47.6173.9-32.339.3000114.5S212 M215 R216 T348 N353 M354S212-P350 VanDerWaalsContact CB-O 3.26Å; S212-P350 WeakPolarHBondContact CB-O 3.42Å; S212-P350 VanDerWaalsContact O-CB 3.29Å; S212-P350 WeakPolarHBondContact O-CB 3.46Å; S212-P350 PolarHBondContact OG-O 3.5Å; M215-P350 HydrophobicContact CB-CG 4.15Å; R216-P350 HydrophobicContact CG-CB 3.97Å; R216-P350 HydrophobicContact CG-CG 3.75Å; T348-P350 VanDerWaalsContact C-N 3.34Å; P350-N353 PolarHBondContact O-N 2.89Å; P350-M354 PolarHBondContact O-N 2.74Å
351L94.6Very high93Very high70 Ų7023.7 Ų23.737%0.36613%0.134SC..Hα-helixtrans-70.4-42-174.5-178.359.9000111.4T348 I349 N353 M354 M355T348-L351 PolarHBondContact O-N 3.47Å; T348-L351 VanDerWaalsContact O-N 3.08Å; T348-L351 WeakPolarHBondContact OG1-CB 3.48Å; T348-L351 PolarHBondContact OG1-N 3.38Å; I349-L351 PolarHBondContact O-N 3.13Å; L351-N353 VanDerWaalsContact C-N 3.32Å; L351-N353 PolarHBondContact O-N 3.44Å; L351-M354 WeakPolarHBondContact O-CB 3.3Å; L351-M354 PolarHBondContact O-N 3.29Å; L351-M354 VanDerWaalsContact O-N 3.16Å; L351-M355 HydrophobicContact CD1-CE 3.89Å; L351-M355 HydrophobicContact CD2-CE 4Å; L351-M355 HydrophobicContact CG-CE 3.67Å; L351-M355 WeakPolarHBondContact O-CG 3.36Å; L351-M355 PolarHBondContact O-N 3.14Å
352S95.5Very high92.8Very high0 Ų026.8 Ų26.80%015%0.154CC..Hα-helixtrans-59.5-43.2175.3-59.80000111.9P338 I341 E342 T348 M355 I356P338-S352 WeakPolarHBondContact O-CB 3.5Å; I341-S352 WeakPolarHBondContact CG2-OG 3.45Å; E342-S352 PolarHBondContact N-OG 3.37Å; T348-S352 PolarHBondContact O-N 3.48Å; T348-S352 PolarHBondContact O-OG 3.46Å; S352-M355 PolarHBondContact O-N 2.98Å; S352-I356 PolarHBondContact O-N 3.32Å
353N96.1Very high92.8Very high0 Ų029 Ų290%017%0.166CC..Hα-helixtrans-64.4-38.9175-79.6-29.3000112.6S45 P338 I349 P350 L351 M355 I356 G357S45-N353 WeakPolarHBondContact CA-OD1 3.45Å; S45-N353 WeakPolarHBondContact CB-OD1 3.41Å; S45-N353 PolarHBondContact O-ND2 3.04Å; P338-N353 WeakPolarHBondContact CB-OD1 3.22Å; I349-N353 WeakPolarHBondContact O-CB 3.15Å; I349-N353 PolarHBondContact O-N 3.14Å; I349-N353 VanDerWaalsContact O-N 3.1Å; I349-N353 PolarHBondContact O-ND2 3.24Å; P350-N353 PolarHBondContact O-N 2.89Å; L351-N353 VanDerWaalsContact C-N 3.32Å; L351-N353 PolarHBondContact O-N 3.44Å; N353-M355 VanDerWaalsContact C-N 3.34Å; N353-M355 PolarHBondContact O-N 3.32Å; N353-I356 PolarHBondContact O-N 3.05Å; N353-G357 PolarHBondContact O-N 3.13Å
354M95.8Very high92.8Very high73 Ų7328.3 Ų28.336%0.3617%0.166SC..Hα-helixtrans-63.5-38.8176-176.15872.600112V209 P350 L351 I356 G358V209-M354 HydrophobicContact CG1-CE 4.31Å; V209-M354 HydrophobicContact CG2-SD 4.4Å; P350-M354 PolarHBondContact O-N 2.74Å; L351-M354 WeakPolarHBondContact O-CB 3.3Å; L351-M354 PolarHBondContact O-N 3.29Å; L351-M354 VanDerWaalsContact O-N 3.16Å; M354-I356 VanDerWaalsContact C-N 3.33Å; M354-I356 PolarHBondContact O-N 2.97Å; M354-G358 VanDerWaalsContact O-CA 3.3Å; M354-G358 WeakPolarHBondContact O-CA 3.15Å; M354-G358 PolarHBondContact O-N 3.09Å
355M94.4Very high92.5Very high25 Ų2530.7 Ų30.712%0.12318%0.18CC..Iπ-helixtrans-62.9-40177.5-70.2171.318000111.9I341 L351 S352 N353 I359 G360 L496 I500I341-M355 HydrophobicContact CD1-CB 4.46Å; I341-M355 HydrophobicContact CG2-SD 3.98Å; L351-M355 HydrophobicContact CD1-CE 3.89Å; L351-M355 HydrophobicContact CD2-CE 4Å; L351-M355 HydrophobicContact CG-CE 3.67Å; L351-M355 WeakPolarHBondContact O-CG 3.36Å; L351-M355 PolarHBondContact O-N 3.14Å; S352-M355 PolarHBondContact O-N 2.98Å; N353-M355 VanDerWaalsContact C-N 3.34Å; N353-M355 PolarHBondContact O-N 3.32Å; M355-I359 WeakPolarHBondContact O-CB 3.36Å; M355-I359 PolarHBondContact O-N 3.2Å; M355-G360 PolarHBondContact O-N 2.82Å; M355-G360 VanDerWaalsContact O-N 3.09Å; M355-L496 HydrophobicContact CE-CD1 4.39Å; M355-L496 HydrophobicContact CE-CD2 3.77Å; M355-L496 HydrophobicContact CE-CG 4.25Å; M355-L496 HydrophobicContact SD-CD1 4.25Å; M355-I500 HydrophobicContact CB-CD1 4.12Å; M355-I500 HydrophobicContact CG-CD1 4.24Å; M355-I500 HydrophobicContact SD-CD1 3.67Å; M355-I500 HydrophobicContact SD-CG1 3.97Å
356I93.8Very high92.5Very high9 Ų934.8 Ų34.85%0.04620%0.202CC..Iπ-helixtrans-70.8-52.3176.9-55-46.9000111.3F208 M337 P338 I341 S352 N353 M354 G360 M361 M503F208-I356 HydrophobicContact CD1-CB 4.16Å; F208-I356 HydrophobicContact CD1-CG2 4.14Å; F208-I356 HydrophobicContact CD2-CG2 4.17Å; F208-I356 HydrophobicContact CE1-CB 4.47Å; F208-I356 HydrophobicContact CE1-CG2 4.16Å; F208-I356 HydrophobicContact CE2-CG2 4.18Å; F208-I356 HydrophobicContact CG-CB 4.41Å; F208-I356 HydrophobicContact CG-CG2 4.17Å; F208-I356 HydrophobicContact CZ-CG2 4.19Å; M337-I356 HydrophobicContact CB-CD1 3.99Å; M337-I356 HydrophobicContact CG-CD1 3.62Å; P338-I356 HydrophobicContact CG-CG1 3.9Å; I341-I356 HydrophobicContact CD1-CD1 3.77Å; S352-I356 PolarHBondContact O-N 3.32Å; N353-I356 PolarHBondContact O-N 3.05Å; M354-I356 VanDerWaalsContact C-N 3.33Å; M354-I356 PolarHBondContact O-N 2.97Å; I356-G360 WeakPolarHBondContact O-CA 3.49Å; I356-G360 PolarHBondContact O-N 2.91Å; I356-M361 HydrophobicContact CG2-CE 4.35Å; I356-M361 PolarHBondContact O-N 3.23Å; I356-M503 HydrophobicContact CD1-CE 3.45Å; I356-M503 VanDerWaalsContact CD1-CE 3.45Å; I356-M503 HydrophobicContact CD1-SD 4.18Å
357G92.1Very high92.6Very high3 Ų333.3 Ų33.33%0.03119%0.192CC..Iπ-helixtrans-73.4-37.8-174.700000114.4N353 P362N353-G357 PolarHBondContact O-N 3.13Å; G357-P362 WeakPolarHBondContact O-CD 3.41Å
358G91.4Very high92.5Very high37 Ų3733.4 Ų33.438%0.38120%0.195SC..Iπ-helixtrans-91.3-24.7-174.400000115M354M354-G358 VanDerWaalsContact O-CA 3.3Å; M354-G358 WeakPolarHBondContact O-CA 3.15Å; M354-G358 PolarHBondContact O-N 3.09Å
359I90.7Very high92.3Very high79 Ų7936.1 Ų36.141%0.40521%0.211SC..Iπ-helixtrans-117.8-53.1-179.7-56.4174.1000110.8M355 P362 L363 I500M355-I359 WeakPolarHBondContact O-CB 3.36Å; M355-I359 PolarHBondContact O-N 3.2Å; I359-P362 WeakPolarHBondContact O-CD 3.21Å; I359-L363 HydrophobicContact CG2-CD1 3.96Å; I359-L363 WeakPolarHBondContact O-CG 3.41Å; I359-L363 PolarHBondContact O-N 2.9Å; I359-I500 HydrophobicContact CD1-CG2 4.18Å
360G89.8Confident92.2Very high5 Ų539.5 Ų39.55%0.05223%0.229CC..Iπ-helixtrans-61.7-49.5-17400000114.2M355 I356 A364 S507M355-G360 PolarHBondContact O-N 2.82Å; M355-G360 VanDerWaalsContact O-N 3.09Å; I356-G360 WeakPolarHBondContact O-CA 3.49Å; I356-G360 PolarHBondContact O-N 2.91Å; G360-A364 PolarHBondContact O-N 3.17Å; G360-A364 VanDerWaalsContact O-N 3.1Å; G360-S507 PolarHBondContact O-OG 2.76Å
361M90.3Very high92Very high41 Ų4139.3 Ų39.320%0.20223%0.228CC..Hα-helixtrans-69.1-44.2-177.4-66.5-70.2-17900113.5A205 F208 I356 L363 A364 V365A205-M361 HydrophobicContact CB-CB 3.6Å; A205-M361 HydrophobicContact CB-CG 4.01Å; F208-M361 HydrophobicContact CD2-CE 4.09Å; F208-M361 HydrophobicContact CE2-CE 3.84Å; I356-M361 HydrophobicContact CG2-CE 4.35Å; I356-M361 PolarHBondContact O-N 3.23Å; M361-L363 VanDerWaalsContact C-N 3.34Å; M361-L363 PolarHBondContact O-N 3.35Å; M361-A364 WeakPolarHBondContact O-CB 3.31Å; M361-A364 PolarHBondContact O-N 3.11Å; M361-A364 VanDerWaalsContact O-N 3.16Å; M361-V365 PolarHBondContact O-N 2.86Å
362P90.8Very high91.5Very high65 Ų6537 Ų3742%0.42222%0.221SC..Hα-helixtrans-59.6-40.5174.3-28.838000113.7G357 I359 A364 V365 L366G357-P362 WeakPolarHBondContact O-CD 3.41Å; I359-P362 WeakPolarHBondContact O-CD 3.21Å; P362-A364 VanDerWaalsContact C-N 3.32Å; P362-A364 PolarHBondContact O-N 3.43Å; P362-V365 PolarHBondContact O-N 3.49Å; P362-L366 PolarHBondContact O-N 2.64Å
363L92.8Very high91.1Very high56 Ų5639.5 Ų39.529%0.29324%0.241SC..Hα-helixtrans-64.6-36.5175.1-74.5175.4000112.2I359 M361 L366 G367 F508I359-L363 HydrophobicContact CG2-CD1 3.96Å; I359-L363 WeakPolarHBondContact O-CG 3.41Å; I359-L363 PolarHBondContact O-N 2.9Å; M361-L363 VanDerWaalsContact C-N 3.34Å; M361-L363 PolarHBondContact O-N 3.35Å; L363-L366 PolarHBondContact O-N 3.25Å; L363-G367 PolarHBondContact O-N 3.1Å; L363-F508 WeakPolarHBondContact O-CD2 3.21Å
364A91.2Very high90.8Very high16 Ų1641.9 Ų41.913%0.13225%0.254CS..Hα-helixtrans-61.2-47.7173.100000111.5G360 M361 P362 L366 G367 V368 S511G360-A364 PolarHBondContact O-N 3.17Å; G360-A364 VanDerWaalsContact O-N 3.1Å; M361-A364 WeakPolarHBondContact O-CB 3.31Å; M361-A364 PolarHBondContact O-N 3.11Å; M361-A364 VanDerWaalsContact O-N 3.16Å; P362-A364 VanDerWaalsContact C-N 3.32Å; P362-A364 PolarHBondContact O-N 3.43Å; A364-L366 PolarHBondContact O-N 3.05Å; A364-G367 WeakPolarHBondContact O-CA 3.3Å; A364-G367 PolarHBondContact O-N 3.21Å; A364-G367 VanDerWaalsContact O-N 3.11Å; A364-V368 PolarHBondContact O-N 3.46Å; A364-S511 WeakPolarHBondContact CA-OG 3.45Å; A364-S511 VanDerWaalsContact CB-OG 3.23Å; A364-S511 WeakPolarHBondContact CB-OG 3.31Å; A364-S511 WeakPolarHBondContact O-CB 3.31Å
365V88.4Confident90.3Very high50 Ų5038.8 Ų38.830%0.30324%0.238SC..Hα-helixtrans-58.4-46.5176.8173.90000111.3M361 P362 G367 V368 V369M361-V365 PolarHBondContact O-N 2.86Å; P362-V365 PolarHBondContact O-N 3.49Å; V365-G367 VanDerWaalsContact C-N 3.26Å; V365-G367 PolarHBondContact O-N 3.36Å; V365-V368 PolarHBondContact O-N 3.49Å; V365-V369 WeakPolarHBondContact O-CG2 3.34Å; V365-V369 PolarHBondContact O-N 2.82Å; V365-V369 VanDerWaalsContact O-N 3.1Å
366L91.6Very high89.8Confident86 Ų8647.4 Ų47.445%0.4527%0.27SS..Hα-helixtrans-58.4-40.6176.6-176.263.2000111.6P362 L363 A364 V369 L370 F508P362-L366 PolarHBondContact O-N 2.64Å; L363-L366 PolarHBondContact O-N 3.25Å; A364-L366 PolarHBondContact O-N 3.05Å; L366-V369 PolarHBondContact O-N 3.09Å; L366-L370 HydrophobicContact CD1-CD1 4.13Å; L366-L370 HydrophobicContact CD1-CG 4.23Å; L366-L370 HydrophobicContact CG-CD1 4.05Å; L366-L370 HydrophobicContact CG-CG 4.48Å; L366-L370 WeakPolarHBondContact O-CB 3.45Å; L366-L370 WeakPolarHBondContact O-CG 3.45Å; L366-L370 PolarHBondContact O-N 2.81Å; L366-F508 HydrophobicContact CB-CD2 4.49Å; L366-F508 HydrophobicContact CB-CE2 4.43Å; L366-F508 HydrophobicContact CD2-CE2 4.31Å; L366-F508 HydrophobicContact CG-CD2 4.47Å; L366-F508 HydrophobicContact CG-CE2 4.03Å
367G93.1Very high89.5Confident0 Ų056.9 Ų56.90%031%0.305CS..Hα-helixtrans-57.8-53.1174.500000112.5L363 A364 V365 V369 L370 G371 F508 F512L363-G367 PolarHBondContact O-N 3.1Å; A364-G367 WeakPolarHBondContact O-CA 3.3Å; A364-G367 PolarHBondContact O-N 3.21Å; A364-G367 VanDerWaalsContact O-N 3.11Å; V365-G367 VanDerWaalsContact C-N 3.26Å; V365-G367 PolarHBondContact O-N 3.36Å; G367-V369 VanDerWaalsContact C-N 3.32Å; G367-V369 PolarHBondContact O-N 2.85Å; G367-L370 PolarHBondContact O-N 3.23Å; G367-G371 PolarHBondContact O-N 2.67Å; G367-F508 VanDerWaalsContact CA-CE2 3.46Å; G367-F512 VanDerWaalsContact O-CA 3.3Å; G367-F512 WeakPolarHBondContact O-CA 3.44Å
368V89.6Confident89.4Confident45 Ų4563 Ų6327%0.27333%0.331SS..Hα-helixtrans-56.3-46.2179.8177.40000111.5A364 V365 G371 G372 T515A364-V368 PolarHBondContact O-N 3.46Å; V365-V368 PolarHBondContact O-N 3.49Å; V368-G371 PolarHBondContact O-N 3.19Å; V368-G372 PolarHBondContact O-N 2.85Å; V368-T515 WeakPolarHBondContact CG1-OG1 3.24Å; V368-T515 PolarHBondContact O-OG1 2.61Å
369V87.7Confident89.2Confident90 Ų9067.8 Ų67.855%0.54535%0.348SS..Hα-helixtrans-64.2-48.1-179.6173.40000110.9V365 L366 G367 G371 G372 A373V365-V369 WeakPolarHBondContact O-CG2 3.34Å; V365-V369 PolarHBondContact O-N 2.82Å; V365-V369 VanDerWaalsContact O-N 3.1Å; L366-V369 PolarHBondContact O-N 3.09Å; G367-V369 VanDerWaalsContact C-N 3.32Å; G367-V369 PolarHBondContact O-N 2.85Å; V369-G371 VanDerWaalsContact C-N 3.34Å; V369-G371 PolarHBondContact O-N 3.33Å; V369-G372 PolarHBondContact O-N 3.01Å; V369-A373 WeakPolarHBondContact O-CB 3.48Å; V369-A373 PolarHBondContact O-N 3.42Å
370L91.4Very high89Confident76 Ų7665.5 Ų65.540%0.39834%0.336SS..Hα-helixtrans-65.7-36179-72.3-179.5000112.3L366 G367 G372 A373 L374 F508 F512L366-L370 HydrophobicContact CD1-CD1 4.13Å; L366-L370 HydrophobicContact CD1-CG 4.23Å; L366-L370 HydrophobicContact CG-CD1 4.05Å; L366-L370 HydrophobicContact CG-CG 4.48Å; L366-L370 WeakPolarHBondContact O-CB 3.45Å; L366-L370 WeakPolarHBondContact O-CG 3.45Å; L366-L370 PolarHBondContact O-N 2.81Å; G367-L370 PolarHBondContact O-N 3.23Å; L370-G372 VanDerWaalsContact C-N 3.33Å; L370-G372 PolarHBondContact O-N 2.97Å; L370-A373 PolarHBondContact O-N 3.32Å; L370-L374 WeakPolarHBondContact O-CB 3.48Å; L370-L374 PolarHBondContact O-N 2.76Å; L370-F508 HydrophobicContact CD1-CE2 3.8Å; L370-F508 HydrophobicContact CD1-CZ 3.73Å; L370-F512 HydrophobicContact CB-CD2 4.31Å
371G90.6Very high89.1Confident0 Ų068.8 Ų68.80%036%0.358CS..Hα-helixtrans-61-41.3172.800000112.4G367 V368 V369 M375 F512G367-G371 PolarHBondContact O-N 2.67Å; V368-G371 PolarHBondContact O-N 3.19Å; V369-G371 VanDerWaalsContact C-N 3.34Å; V369-G371 PolarHBondContact O-N 3.33Å; G371-M375 VanDerWaalsContact O-CG 3.31Å; G371-M375 WeakPolarHBondContact O-CG 3.29Å; G371-M375 PolarHBondContact O-N 3.13Å; G371-M375 VanDerWaalsContact O-N 3.16Å; G371-F512 VanDerWaalsContact CA-CD2 3.47Å; G371-F512 VanDerWaalsContact CA-CE2 3.48Å
372G85.4Confident89Confident22 Ų2268.1 Ų68.123%0.22736%0.356CS..Hα-helixtrans-68.1-44.8174.100000113.4V368 V369 L370 L374 M375 R376V368-G372 PolarHBondContact O-N 2.85Å; V369-G372 PolarHBondContact O-N 3.01Å; L370-G372 VanDerWaalsContact C-N 3.33Å; L370-G372 PolarHBondContact O-N 2.97Å; G372-L374 VanDerWaalsContact C-N 3.31Å; G372-L374 PolarHBondContact O-N 3.05Å; G372-M375 PolarHBondContact O-N 3.44Å; G372-R376 PolarHBondContact O-N 3.41Å
373A85.3Confident89.1Confident51 Ų5171.1 Ų71.142%0.42136%0.359SS..Hα-helixtrans-60.4-41.2177.500000111.7V369 L370 R376 R377V369-A373 WeakPolarHBondContact O-CB 3.48Å; V369-A373 PolarHBondContact O-N 3.42Å; L370-A373 PolarHBondContact O-N 3.32Å; A373-R376 PolarHBondContact O-N 3.14Å; A373-R377 WeakPolarHBondContact O-CB 3.35Å; A373-R377 PolarHBondContact O-N 3.03Å
374L91.3Very high89Confident50 Ų5069.4 Ų69.426%0.26236%0.355SS..Hα-helixtrans-65.3-46.2177.3-166.274.7000111.9L370 G372 R376 R377 F378 L388 F512L370-L374 WeakPolarHBondContact O-CB 3.48Å; L370-L374 PolarHBondContact O-N 2.76Å; G372-L374 VanDerWaalsContact C-N 3.31Å; G372-L374 PolarHBondContact O-N 3.05Å; L374-R376 VanDerWaalsContact C-N 3.27Å; L374-R376 PolarHBondContact O-N 3.31Å; L374-R377 PolarHBondContact O-N 3.16Å; L374-F378 HydrophobicContact CD1-CD2 3.53Å; L374-F378 HydrophobicContact CD1-CE2 3.36Å; L374-F378 HydrophobicContact CG-CD2 3.94Å; L374-F378 HydrophobicContact CG-CE2 4.27Å; L374-F378 PolarHBondContact O-N 3.32Å; L374-F378 VanDerWaalsContact O-N 3.14Å; L374-L388 HydrophobicContact CD2-CD1 3.87Å; L374-L388 HydrophobicContact CD2-CD2 3.79Å; L374-L388 HydrophobicContact CD2-CG 4.5Å; L374-F512 HydrophobicContact CB-CE2 4.49Å; L374-F512 HydrophobicContact CD2-CE2 4.19Å; L374-F512 HydrophobicContact CD2-CZ 3.57Å
375M85.7Confident89.1Confident8 Ų868.6 Ų68.64%0.03935%0.348CS..Hα-helixtrans-57.6-40.2176.4-79.6-69.7-64.300112.4G371 G372 N379 M380 A385 P516 M519G371-M375 VanDerWaalsContact O-CG 3.31Å; G371-M375 WeakPolarHBondContact O-CG 3.29Å; G371-M375 PolarHBondContact O-N 3.13Å; G371-M375 VanDerWaalsContact O-N 3.16Å; G372-M375 PolarHBondContact O-N 3.44Å; M375-N379 PolarHBondContact O-N 2.84Å; M375-M380 HydrophobicContact CE-CB 4.28Å; M375-M380 PolarHBondContact O-N 3.31Å; M375-M380 HydrophobicContact SD-CB 3.79Å; M375-M380 HydrophobicContact SD-CG 4.23Å; M375-M380 HydrophobicContact SD-SD 3.81Å; M375-A385 HydrophobicContact CE-CB 3.92Å; M375-A385 HydrophobicContact SD-CB 3.84Å; M375-P516 HydrophobicContact CG-CB 3.91Å; M375-P516 HydrophobicContact CG-CG 3.74Å; M375-P516 HydrophobicContact SD-CB 3.83Å; M375-P516 HydrophobicContact SD-CG 4.25Å; M375-M519 HydrophobicContact CE-CB 3.91Å; M375-M519 HydrophobicContact CE-CG 4.42Å
376R83.8Confident89.4Confident206 Ų20666.2 Ų66.278%0.77733%0.334SS*.Hα-helixtrans-70-50.8176.7-178.6178.6176.7177.6-0.7111.8G372 A373 L374 F378 N379G372-R376 PolarHBondContact O-N 3.41Å; A373-R376 PolarHBondContact O-N 3.14Å; L374-R376 VanDerWaalsContact C-N 3.27Å; L374-R376 PolarHBondContact O-N 3.31Å; R376-F378 VanDerWaalsContact C-N 3.29Å; R376-F378 PolarHBondContact O-N 2.87Å; R376-N379 PolarHBondContact O-N 3.06Å; R376-N379 PolarHBondContact O-OD1 3.48Å
377R87.1Confident89.6Confident208 Ų20868.2 Ų68.279%0.78534%0.339SS*.Hα-helixtrans-60.2-38.8-174.5-174.3176-178.4177.10.6112.5A373 L374A373-R377 WeakPolarHBondContact O-CB 3.35Å; A373-R377 PolarHBondContact O-N 3.03Å; L374-R377 PolarHBondContact O-N 3.16Å
378F89.3Confident89.7Confident131 Ų13169.8 Ų69.858%0.57535%0.347SS*.THydrogen-bonded Turntrans-97.62.7-177.5-70.6-71.7000114.1L374 R376 M380L374-F378 HydrophobicContact CD1-CD2 3.53Å; L374-F378 HydrophobicContact CD1-CE2 3.36Å; L374-F378 HydrophobicContact CG-CD2 3.94Å; L374-F378 HydrophobicContact CG-CE2 4.27Å; L374-F378 PolarHBondContact O-N 3.32Å; L374-F378 VanDerWaalsContact O-N 3.14Å; R376-F378 VanDerWaalsContact C-N 3.29Å; R376-F378 PolarHBondContact O-N 2.87Å; F378-M380 HydrophobicContact CB-CG 3.63Å; F378-M380 HydrophobicContact CB-SD 4.42Å; F378-M380 PolarHBondContact O-N 3.4Å; F378-M380 VanDerWaalsContact O-N 3.09Å
379N87.9Confident90Very high138 Ų13867.7 Ų67.774%0.73833%0.334SS*.THydrogen-bonded Turntrans42.147.3-174.9-82-32.8000112.4M375 R376 S381M375-N379 PolarHBondContact O-N 2.84Å; R376-N379 PolarHBondContact O-N 3.06Å; R376-N379 PolarHBondContact O-OD1 3.48Å; N379-S381 PolarHBondContact O-N 3.44Å
380M85.8Confident90.4Very high31 Ų3164.1 Ų64.115%0.15331%0.312CS..  trans-63.5131.8-166.1-62.4-178.670.900111.1M375 F378 G384 L388 R523M375-M380 HydrophobicContact CE-CB 4.28Å; M375-M380 PolarHBondContact O-N 3.31Å; M375-M380 HydrophobicContact SD-CB 3.79Å; M375-M380 HydrophobicContact SD-CG 4.23Å; M375-M380 HydrophobicContact SD-SD 3.81Å; F378-M380 HydrophobicContact CB-CG 3.63Å; F378-M380 HydrophobicContact CB-SD 4.42Å; F378-M380 PolarHBondContact O-N 3.4Å; F378-M380 VanDerWaalsContact O-N 3.09Å; M380-G384 WeakPolarHBondContact CE-O 3.13Å; M380-L388 HydrophobicContact CE-CB 3.77Å; M380-L388 HydrophobicContact CE-CD2 3.9Å; M380-L388 HydrophobicContact CE-CG 4.35Å; M380-L388 HydrophobicContact SD-CD2 3.91Å; M380-R523 PolarHBondContact O-NH1 3.26Å
381S91.5Very high90.7Very high74 Ų7463.1 Ų63.152%0.51732%0.315SS..  trans-69.4168171.269.20000111.6N379 R383 G384 A385N379-S381 PolarHBondContact O-N 3.44Å; S381-R383 PolarHBondContact O-N 3.01Å; S381-G384 WeakPolarHBondContact O-CA 3.45Å; S381-G384 PolarHBondContact O-N 3.34Å; S381-G384 PolarHBondContact OG-N 3.32Å; S381-A385 PolarHBondContact O-N 2.92Å
382V89.4Confident91Very high28 Ų2863.5 Ų63.517%0.1732%0.319CS..Hα-helixtrans-55.7-37.5176179.90000111.7S386 M520 R523 T524 L608V382-S386 WeakPolarHBondContact O-CB 3.42Å; V382-S386 PolarHBondContact O-N 3.38Å; V382-M520 HydrophobicContact CG1-CE 4.35Å; V382-M520 HydrophobicContact CG1-CG 4.29Å; V382-R523 HydrophobicContact CG2-CB 3.53Å; V382-R523 HydrophobicContact CG2-CG 4.46Å; V382-T524 HydrophobicContact CG1-CG2 3.79Å; V382-T524 HydrophobicContact CG2-CG2 4.48Å; V382-L608 HydrophobicContact CG1-CD1 4.12Å; V382-L608 HydrophobicContact CG1-CD2 4.04Å
383R91.6Very high91.5Very high128 Ų12862.5 Ų62.548%0.48331%0.308SS..Hα-helixtrans-67.3-40175.2-65.8-176-171.9158.311.8112S381 K387 L608 A612S381-R383 PolarHBondContact O-N 3.01Å; R383-K387 WeakPolarHBondContact O-CG 3.31Å; R383-K387 PolarHBondContact O-N 3.24Å; R383-K387 VanDerWaalsContact O-N 3.15Å; R383-L608 HydrophobicContact CG-CB 4.38Å; R383-A612 VanDerWaalsContact CZ-CB 3.42Å
384G92.4Very high92.1Very high19 Ų1964 Ų6420%0.19631%0.309CS..Hα-helixtrans-63.2-47.8175.100000111.8M380 S381 S386 K387 L388M380-G384 WeakPolarHBondContact CE-O 3.13Å; S381-G384 WeakPolarHBondContact O-CA 3.45Å; S381-G384 PolarHBondContact O-N 3.34Å; S381-G384 PolarHBondContact OG-N 3.32Å; G384-S386 VanDerWaalsContact C-N 3.34Å; G384-S386 PolarHBondContact O-N 3.35Å; G384-K387 PolarHBondContact O-N 3.42Å; G384-L388 PolarHBondContact O-N 3.44Å
385A92.5Very high92.3Very high0 Ų066 Ų660%032%0.319CS..Hα-helixtrans-59.4-43.6176.800000111.8M375 S381 K387 L388 C389 M520M375-A385 HydrophobicContact CE-CB 3.92Å; M375-A385 HydrophobicContact SD-CB 3.84Å; S381-A385 PolarHBondContact O-N 2.92Å; A385-K387 VanDerWaalsContact C-N 3.34Å; A385-K387 PolarHBondContact O-N 2.88Å; A385-L388 WeakPolarHBondContact O-CB 3.48Å; A385-L388 PolarHBondContact O-N 2.88Å; A385-C389 PolarHBondContact O-N 3.05Å; A385-C389 PolarHBondContact O-SG 3.42Å; A385-C389 VanDerWaalsContact O-SG 3.4Å; A385-M520 HydrophobicContact CB-CG 3.66Å; A385-M520 HydrophobicContact CB-SD 3.88Å
386S94.8Very high92.8Very high0 Ų065.7 Ų65.70%032%0.317CS..Hα-helixtrans-62.2-38.9177.3-164.80000112.7V382 G384 T390 M605V382-S386 WeakPolarHBondContact O-CB 3.42Å; V382-S386 PolarHBondContact O-N 3.38Å; G384-S386 VanDerWaalsContact C-N 3.34Å; G384-S386 PolarHBondContact O-N 3.35Å; S386-T390 WeakPolarHBondContact O-CB 3.22Å; S386-T390 PolarHBondContact O-N 3.49Å; S386-T390 PolarHBondContact O-OG1 3.27Å; S386-M605 WeakPolarHBondContact OG-CG 3.21Å
387K95.3Very high93.4Very high128 Ų12856.9 Ų56.956%0.55729%0.286SS*.Hα-helixtrans-64.9-44.2173.9-73178-178.8-176.20111.4R383 G384 A385 T390 A391 M605R383-K387 WeakPolarHBondContact O-CG 3.31Å; R383-K387 PolarHBondContact O-N 3.24Å; R383-K387 VanDerWaalsContact O-N 3.15Å; G384-K387 PolarHBondContact O-N 3.42Å; A385-K387 VanDerWaalsContact C-N 3.34Å; A385-K387 PolarHBondContact O-N 2.88Å; K387-T390 PolarHBondContact O-N 3.03Å; K387-A391 WeakPolarHBondContact O-CB 3.47Å; K387-A391 PolarHBondContact O-N 3.31Å; K387-M605 HydrophobicContact CD-CE 4.3Å; K387-M605 HydrophobicContact CG-CE 3.42Å; K387-M605 VanDerWaalsContact CG-CE 3.42Å; K387-M605 HydrophobicContact CG-SD 3.7Å
388L95.6Very high93.8Very high33 Ų3352.6 Ų52.617%0.17328%0.277CS..Hα-helixtrans-60.5-49.6177.9179.768.6000111.4L374 M380 G384 A385 T390 A391 A392 F512 P516L374-L388 HydrophobicContact CD2-CD1 3.87Å; L374-L388 HydrophobicContact CD2-CD2 3.79Å; L374-L388 HydrophobicContact CD2-CG 4.5Å; M380-L388 HydrophobicContact CE-CB 3.77Å; M380-L388 HydrophobicContact CE-CD2 3.9Å; M380-L388 HydrophobicContact CE-CG 4.35Å; M380-L388 HydrophobicContact SD-CD2 3.91Å; G384-L388 PolarHBondContact O-N 3.44Å; A385-L388 WeakPolarHBondContact O-CB 3.48Å; A385-L388 PolarHBondContact O-N 2.88Å; L388-T390 VanDerWaalsContact C-N 3.32Å; L388-T390 PolarHBondContact O-N 3.25Å; L388-A391 PolarHBondContact O-N 3.43Å; L388-A392 WeakPolarHBondContact O-CB 3.47Å; L388-A392 PolarHBondContact O-N 2.99Å; L388-F512 HydrophobicContact CD1-CE1 3.9Å; L388-F512 HydrophobicContact CD1-CZ 4.09Å; L388-F512 HydrophobicContact CD2-CE1 4.03Å; L388-F512 HydrophobicContact CD2-CZ 4.08Å; L388-F512 HydrophobicContact CG-CE1 3.97Å; L388-F512 HydrophobicContact CG-CZ 4.37Å; L388-P516 HydrophobicContact CD2-CB 4.42Å; L388-P516 HydrophobicContact CD2-CG 4.04Å
389C96.2Very high94.1Very high0 Ų046.9 Ų46.90%025%0.254CS..Hα-helixtrans-59.5-43.8176.9-67.30000111.3A385 A391 A392 I393 S517 F601A385-C389 PolarHBondContact O-N 3.05Å; A385-C389 PolarHBondContact O-SG 3.42Å; A385-C389 VanDerWaalsContact O-SG 3.4Å; C389-A391 PolarHBondContact O-N 3.5Å; C389-A392 PolarHBondContact O-N 3.33Å; C389-I393 WeakPolarHBondContact O-CB 3.28Å; C389-I393 VanDerWaalsContact O-CG1 3.28Å; C389-I393 WeakPolarHBondContact O-CG1 3.36Å; C389-I393 PolarHBondContact O-N 3.27Å; C389-S517 PolarHBondContact SG-OG 3.09Å; C389-F601 HydrophobicContact CB-CD1 3.88Å; C389-F601 HydrophobicContact CB-CD2 4.2Å; C389-F601 HydrophobicContact CB-CE1 3.71Å; C389-F601 HydrophobicContact CB-CE2 4.04Å; C389-F601 HydrophobicContact CB-CG 4.14Å; C389-F601 HydrophobicContact CB-CZ 3.81Å
390T96.8Very high94.4Very high15 Ų1540.4 Ų40.49%0.09222%0.219CC..Hα-helixtrans-60.6-47.5177.6-52.90000111.4S386 K387 L388 I393 L394 L598 L602S386-T390 WeakPolarHBondContact O-CB 3.22Å; S386-T390 PolarHBondContact O-N 3.49Å; S386-T390 PolarHBondContact O-OG1 3.27Å; K387-T390 PolarHBondContact O-N 3.03Å; L388-T390 VanDerWaalsContact C-N 3.32Å; L388-T390 PolarHBondContact O-N 3.25Å; T390-I393 PolarHBondContact O-N 2.66Å; T390-L394 HydrophobicContact CG2-CD1 4.34Å; T390-L394 WeakPolarHBondContact O-CG 3.42Å; T390-L394 PolarHBondContact O-N 3.1Å; T390-L598 HydrophobicContact CG2-CD1 4Å; T390-L602 HydrophobicContact CG2-CD2 3.65Å; T390-L602 HydrophobicContact CG2-CG 4.25Å
391A97.2Very high94.8Very high55 Ų5542.8 Ų42.846%0.45523%0.232SC..Hα-helixtrans-63.6-42.1178.700000112.2K387 L388 C389 L394 L395K387-A391 WeakPolarHBondContact O-CB 3.47Å; K387-A391 PolarHBondContact O-N 3.31Å; L388-A391 PolarHBondContact O-N 3.43Å; C389-A391 PolarHBondContact O-N 3.5Å; A391-L394 PolarHBondContact O-N 3.31Å; A391-L395 PolarHBondContact O-N 3.02Å
392A96.8Very high95Very high9 Ų941.7 Ų41.77%0.07422%0.223CC..Hα-helixtrans-65.2-42.1177.200000112L388 C389 L394 L395 C396 I509 F512 T513L388-A392 WeakPolarHBondContact O-CB 3.47Å; L388-A392 PolarHBondContact O-N 2.99Å; C389-A392 PolarHBondContact O-N 3.33Å; A392-L394 VanDerWaalsContact C-N 3.35Å; A392-L394 PolarHBondContact O-N 2.7Å; A392-L395 WeakPolarHBondContact O-CB 3.45Å; A392-L395 PolarHBondContact O-N 3.15Å; A392-C396 WeakPolarHBondContact O-CB 3.46Å; A392-C396 PolarHBondContact O-N 3.47Å; A392-I509 HydrophobicContact CB-CG2 4.2Å; A392-I509 WeakPolarHBondContact O-CG2 3.49Å; A392-F512 HydrophobicContact CB-CD1 4.21Å; A392-F512 HydrophobicContact CB-CE1 4.42Å; A392-T513 HydrophobicContact CB-CG2 3.4Å; A392-T513 VanDerWaalsContact CB-CG2 3.4Å
393I96.5Very high95.2Very high0 Ų040.4 Ų40.40%022%0.215CC..Hα-helixtrans-67.6-34.7176.2-65.7-59.4000111.9M326 C389 T390 C396 L397 T513 V594 L598 F601M326-I393 HydrophobicContact CE-CD1 3.45Å; M326-I393 VanDerWaalsContact CE-CD1 3.45Å; M326-I393 HydrophobicContact SD-CD1 3.66Å; C389-I393 WeakPolarHBondContact O-CB 3.28Å; C389-I393 VanDerWaalsContact O-CG1 3.28Å; C389-I393 WeakPolarHBondContact O-CG1 3.36Å; C389-I393 PolarHBondContact O-N 3.27Å; T390-I393 PolarHBondContact O-N 2.66Å; I393-C396 VanDerWaalsContact O-CB 3.28Å; I393-C396 WeakPolarHBondContact O-CB 3.49Å; I393-C396 PolarHBondContact O-N 3.32Å; I393-L397 PolarHBondContact O-N 3.14Å; I393-T513 HydrophobicContact CD1-CG2 4.09Å; I393-T513 HydrophobicContact CG1-CG2 4.32Å; I393-V594 HydrophobicContact CG2-CG1 3.79Å; I393-L598 HydrophobicContact CB-CD1 4.44Å; I393-L598 HydrophobicContact CG2-CB 3.68Å; I393-L598 HydrophobicContact CG2-CD1 4.09Å; I393-L598 HydrophobicContact CG2-CG 4.42Å; I393-F601 HydrophobicContact CG1-CD2 3.94Å; I393-F601 HydrophobicContact CG1-CE2 3.92Å
394L96.6Very high95.4Very high83 Ų8335.6 Ų35.644%0.43520%0.199SC..Hα-helixtrans-61.8-44.3170.3-74.5167.6000111.5T390 A391 A392 C396 L397 I398 L598T390-L394 HydrophobicContact CG2-CD1 4.34Å; T390-L394 WeakPolarHBondContact O-CG 3.42Å; T390-L394 PolarHBondContact O-N 3.1Å; A391-L394 PolarHBondContact O-N 3.31Å; A392-L394 VanDerWaalsContact C-N 3.35Å; A392-L394 PolarHBondContact O-N 2.7Å; L394-C396 VanDerWaalsContact C-N 3.29Å; L394-C396 PolarHBondContact O-N 3.01Å; L394-L397 WeakPolarHBondContact O-CB 3.42Å; L394-L397 PolarHBondContact O-N 3.12Å; L394-I398 WeakPolarHBondContact O-CG1 3.46Å; L394-I398 PolarHBondContact O-N 3.49Å; L394-I398 VanDerWaalsContact O-N 3.15Å; L394-L598 HydrophobicContact CD2-CD1 3.97Å; L394-L598 HydrophobicContact CD2-CD2 3.69Å; L394-L598 HydrophobicContact CG-CD1 3.85Å; L394-L598 HydrophobicContact CG-CD2 4.46Å
395L96.4Very high95.5Very high93 Ų9342.4 Ų42.449%0.48722%0.223SC..Hα-helixtrans-63.5-36.7174.6-173.364.7000111.9A391 A392 L397 I398 S399 I509A391-L395 PolarHBondContact O-N 3.02Å; A392-L395 WeakPolarHBondContact O-CB 3.45Å; A392-L395 PolarHBondContact O-N 3.15Å; L395-L397 VanDerWaalsContact C-N 3.34Å; L395-L397 PolarHBondContact O-N 3.29Å; L395-I398 PolarHBondContact O-N 3.25Å; L395-S399 PolarHBondContact O-N 3.49Å; L395-I509 HydrophobicContact CB-CD1 4.45Å; L395-I509 HydrophobicContact CD2-CD1 3.86Å; L395-I509 HydrophobicContact CD2-CG1 4.3Å; L395-I509 HydrophobicContact CG-CD1 3.77Å
396C96.3Very high95.5Very high0 Ų043.9 Ų43.90%023%0.231CC..Hα-helixtrans-58.4-45.3173.9-175.70000111A392 I393 L394 I398 S399 A400 I509 I510 V594A392-C396 WeakPolarHBondContact O-CB 3.46Å; A392-C396 PolarHBondContact O-N 3.47Å; I393-C396 VanDerWaalsContact O-CB 3.28Å; I393-C396 WeakPolarHBondContact O-CB 3.49Å; I393-C396 PolarHBondContact O-N 3.32Å; L394-C396 VanDerWaalsContact C-N 3.29Å; L394-C396 PolarHBondContact O-N 3.01Å; C396-I398 VanDerWaalsContact C-N 3.35Å; C396-I398 PolarHBondContact O-N 3.23Å; C396-S399 PolarHBondContact O-N 3.09Å; C396-S399 PolarHBondContact O-OG 2.93Å; C396-A400 VanDerWaalsContact O-CB 3.23Å; C396-A400 WeakPolarHBondContact O-CB 3.45Å; C396-A400 PolarHBondContact O-N 3.27Å; C396-I509 HydrophobicContact CB-CG2 3.83Å; C396-I510 VanDerWaalsContact SG-CG1 3.58Å; C396-V594 HydrophobicContact CB-CG1 4.31Å
397L95.8Very high95.4Very high22 Ų2244.3 Ų44.312%0.11524%0.236CC..Hα-helixtrans-60.4-43.1175.5-72.8172.7000112.1I393 L394 L395 S399 A400 L401 V591 V594 L598I393-L397 PolarHBondContact O-N 3.14Å; L394-L397 WeakPolarHBondContact O-CB 3.42Å; L394-L397 PolarHBondContact O-N 3.12Å; L395-L397 VanDerWaalsContact C-N 3.34Å; L395-L397 PolarHBondContact O-N 3.29Å; L397-S399 VanDerWaalsContact C-N 3.28Å; L397-S399 PolarHBondContact O-N 3.47Å; L397-A400 PolarHBondContact O-N 3.4Å; L397-L401 WeakPolarHBondContact O-CB 3.48Å; L397-L401 VanDerWaalsContact O-CG 3.29Å; L397-L401 WeakPolarHBondContact O-CG 3.32Å; L397-L401 PolarHBondContact O-N 3.37Å; L397-V591 HydrophobicContact CD2-CG1 4.09Å; L397-V594 HydrophobicContact CD2-CB 3.84Å; L397-V594 HydrophobicContact CD2-CG1 3.4Å; L397-V594 VanDerWaalsContact CD2-CG1 3.4Å; L397-V594 HydrophobicContact CG-CG1 3.58Å; L397-L598 HydrophobicContact CD1-CD2 3.64Å
398I95.7Very high95.2Very high118 Ų11838.3 Ų38.361%0.60521%0.21SC*.Hα-helixtrans-60.1-40.7177.4-64.4168.1000110.8L394 L395 C396 P402L394-I398 WeakPolarHBondContact O-CG1 3.46Å; L394-I398 PolarHBondContact O-N 3.49Å; L394-I398 VanDerWaalsContact O-N 3.15Å; L395-I398 PolarHBondContact O-N 3.25Å; C396-I398 VanDerWaalsContact C-N 3.35Å; C396-I398 PolarHBondContact O-N 3.23Å; I398-P402 WeakPolarHBondContact O-CD 3.43Å; I398-P402 WeakPolarHBondContact O-CG 3.43Å
399S95Very high95Very high11 Ų1140.9 Ų40.98%0.07723%0.23CC..Hα-helixtrans-74.5-30.9176.468.30000113.9L395 C396 L397 T506L395-S399 PolarHBondContact O-N 3.49Å; C396-S399 PolarHBondContact O-N 3.09Å; C396-S399 PolarHBondContact O-OG 2.93Å; L397-S399 VanDerWaalsContact C-N 3.28Å; L397-S399 PolarHBondContact O-N 3.47Å; S399-T506 WeakPolarHBondContact CB-OG1 3.35Å; S399-T506 PolarHBondContact OG-OG1 2.76Å
400A94.1Very high94.7Very high1 Ų141.4 Ų41.41%0.00823%0.233CC..Hα-helixtrans-84.3-36.3-173.200000113.9C396 L397 M403 T506 M590 V591C396-A400 VanDerWaalsContact O-CB 3.23Å; C396-A400 WeakPolarHBondContact O-CB 3.45Å; C396-A400 PolarHBondContact O-N 3.27Å; L397-A400 PolarHBondContact O-N 3.4Å; A400-M403 HydrophobicContact CB-CE 4.01Å; A400-M403 WeakPolarHBondContact O-CB 3.2Å; A400-M403 PolarHBondContact O-N 2.89Å; A400-T506 HydrophobicContact CB-CG2 4.39Å; A400-M590 HydrophobicContact CB-CE 3.96Å; A400-V591 HydrophobicContact CB-CG2 4.48Å
401L94.8Very high94.2Very high81 Ų8142.9 Ų42.942%0.42424%0.239SC..G310 helixtrans-59.9-43.5-177.7-73.9168.6000113.7L397 M403 I404 V591L397-L401 WeakPolarHBondContact O-CB 3.48Å; L397-L401 VanDerWaalsContact O-CG 3.29Å; L397-L401 WeakPolarHBondContact O-CG 3.32Å; L397-L401 PolarHBondContact O-N 3.37Å; L401-M403 PolarHBondContact O-N 3.48Å; L401-I404 HydrophobicContact CD2-CD1 4.38Å; L401-I404 WeakPolarHBondContact O-CB 3.43Å; L401-I404 PolarHBondContact O-N 2.88Å; L401-I404 VanDerWaalsContact O-N 3.15Å; L401-V591 HydrophobicContact CD2-CG1 4.12Å; L401-V591 HydrophobicContact CD2-CG2 4.14Å
402P94.9Very high93.8Very high51 Ų5146.4 Ų46.433%0.33125%0.245SC..G310 helixtrans-57.9-31.6176.6-26.135.3000113.4I398 I404 F405 I406 L502I398-P402 WeakPolarHBondContact O-CD 3.43Å; I398-P402 WeakPolarHBondContact O-CG 3.43Å; P402-I404 PolarHBondContact O-N 3.19Å; P402-F405 PolarHBondContact O-N 2.99Å; P402-I406 WeakPolarHBondContact O-CG1 3.33Å; P402-I406 PolarHBondContact O-N 3.22Å; P402-L502 HydrophobicContact CB-CD1 4.11Å
403M94.4Very high93.4Very high1 Ų146.1 Ų46.11%0.00524%0.242CC..G310 helixtrans-61.2-27.3-179.6-61.6-165-7900112.8A400 L401 F405 I406 F499 L502 M503 T506 L587 M590A400-M403 HydrophobicContact CB-CE 4.01Å; A400-M403 WeakPolarHBondContact O-CB 3.2Å; A400-M403 PolarHBondContact O-N 2.89Å; L401-M403 PolarHBondContact O-N 3.48Å; M403-F405 PolarHBondContact O-N 3.39Å; M403-I406 PolarHBondContact O-N 3.33Å; M403-F499 HydrophobicContact CB-CD2 4.32Å; M403-F499 HydrophobicContact CB-CE2 4.02Å; M403-F499 HydrophobicContact CG-CD2 4.45Å; M403-F499 HydrophobicContact CG-CE2 4.37Å; M403-F499 HydrophobicContact SD-CE2 4.19Å; M403-F499 HydrophobicContact SD-CZ 4.5Å; M403-L502 HydrophobicContact CG-CB 3.82Å; M403-L502 HydrophobicContact CG-CD1 4.17Å; M403-L502 HydrophobicContact SD-CB 4.08Å; M403-M503 HydrophobicContact SD-CB 4.14Å; M403-T506 HydrophobicContact CE-CG2 4.32Å; M403-L587 HydrophobicContact CB-CD1 3.93Å; M403-L587 WeakPolarHBondContact O-CD1 3.5Å; M403-M590 HydrophobicContact CE-CE 3.66Å; M403-M590 HydrophobicContact CE-SD 3.93Å
404I95.4Very high92.9Very high28 Ų2847 Ų4714%0.14425%0.249CC..G310 helixtrans-62.7-27.7176.2-64.6175.2000111.7L401 P402 R583 K584 L587 V591L401-I404 HydrophobicContact CD2-CD1 4.38Å; L401-I404 WeakPolarHBondContact O-CB 3.43Å; L401-I404 PolarHBondContact O-N 2.88Å; L401-I404 VanDerWaalsContact O-N 3.15Å; P402-I404 PolarHBondContact O-N 3.19Å; I404-R583 VanDerWaalsContact O-CD 3.24Å; I404-R583 WeakPolarHBondContact O-CD 3.26Å; I404-R583 WeakPolarHBondContact O-CG 3.43Å; I404-R583 PolarHBondContact O-NE 3.25Å; I404-K584 HydrophobicContact CG2-CG 4.21Å; I404-L587 HydrophobicContact CG1-CB 3.85Å; I404-V591 HydrophobicContact CD1-CG2 3.95Å
405F93.9Very high92.2Very high162 Ų16247.4 Ų47.471%0.71125%0.248SC*.THydrogen-bonded Turntrans-95.1-15.2-178.2-57.1-77.9000112.8P402 M403P402-F405 PolarHBondContact O-N 2.99Å; M403-F405 PolarHBondContact O-N 3.39Å
406I93.7Very high91.6Very high30 Ų3044.2 Ų44.215%0.15423%0.233CC..  trans-95.5108.4-177.2-60.2168.1000110.1P402 M403 L495 F499 L502 R583P402-I406 WeakPolarHBondContact O-CG1 3.33Å; P402-I406 PolarHBondContact O-N 3.22Å; M403-I406 PolarHBondContact O-N 3.33Å; I406-L495 HydrophobicContact CG2-CB 3.94Å; I406-L495 WeakPolarHBondContact CG2-O 3.45Å; I406-F499 HydrophobicContact CG2-CB 3.97Å; I406-F499 HydrophobicContact CG2-CD2 4.4Å; I406-L502 HydrophobicContact CD1-CD1 3.45Å; I406-L502 VanDerWaalsContact CD1-CD1 3.45Å; I406-R583 WeakPolarHBondContact O-CD 3.28Å
407G91.2Very high91Very high10 Ų1047.5 Ų47.510%0.10325%0.246CC..SBendtrans169170.5169.200000112R583G407-R583 VanDerWaalsContact C-NH1 3.33Å; G407-R583 PolarHBondContact O-NH1 3.33Å
408C92Very high90.1Very high2 Ų249.6 Ų49.61%0.01426%0.261CS..PPolyproline II helixtrans-63.8142.7176.1-56.10000113Q344 C492 L579 R583Q344-C408 PolarHBondContact NE2-O 2.88Å; Q344-C408 WeakPolarHBondContact O-CB 3.37Å; Q344-C408 PolarHBondContact O-SG 3.02Å; C408-C492 VanDerWaalsContact CA-SG 3.52Å; C408-C492 HydrophobicContact CB-CB 4.01Å; C408-C492 WeakPolarHBondContact CB-SG 3.29Å; C408-C492 WeakPolarHBondContact SG-CB 3.27Å; C408-C492 CovalentContact SG-SG 1.99Å; C408-C492 PolarHBondContact SG-SG 3.28Å; C408-L579 HydrophobicContact CB-CD1 4.21Å; C408-R583 PolarHBondContact O-NH1 3.07Å
409S90.9Very high88.8Confident86 Ų8650.5 Ų50.560%0.60127%0.267SS*.PPolyproline II helixtrans-70.5155.416856.20000110.2Q411S409-Q411 PolarHBondContact O-N 3.32Å
410T90.6Very high87.1Confident11 Ų1159 Ų597%0.06730%0.297CS..PPolyproline II helixtrans-58.9124.5175.9-49.70000110.1Y417 I562 N578 L579 D580T410-Y417 VanDerWaalsContact CB-CE1 3.44Å; T410-Y417 HydrophobicContact CG2-CD1 3.39Å; T410-Y417 HydrophobicContact CG2-CD2 4.39Å; T410-Y417 HydrophobicContact CG2-CE1 3.37Å; T410-Y417 HydrophobicContact CG2-CE2 4.37Å; T410-Y417 HydrophobicContact CG2-CG 3.92Å; T410-I562 HydrophobicContact CG2-CD1 4.35Å; T410-N578 PolarHBondContact OG1-OD1 3.2Å; T410-L579 PolarHBondContact OG1-N 2.91Å; T410-D580 PolarHBondContact N-OD2 2.9Å; T410-D580 PolarHBondContact OG1-N 3.29Å; T410-D580 VanDerWaalsContact OG1-N 3.16Å; T410-D580 PolarHBondContact OG1-OD2 3.28Å
411Q86.3Confident85Confident46 Ų4667.1 Ų67.122%0.21534%0.34CS..PPolyproline II helixtrans-66.1147-179.667.6-165.7800111.3S409 V413S409-Q411 PolarHBondContact O-N 3.32Å; Q411-V413 HydrophobicContact CG-CG2 3.77Å; Q411-V413 PolarHBondContact O-N 2.83Å
412K88.9Confident82.9Confident130 Ų13066.9 Ų66.957%0.56535%0.346SS*.PPolyproline II helixtrans-77.7116174.7-66.4-179.4-176.8176.10108.4Y417 E447K412-Y417 WeakPolarHBondContact CA-O 3.28Å; K412-E447 PolarHBondContact O-N 2.96Å; K412-E447 VanDerWaalsContact O-N 3.12Å
413V88.8Confident80.9Confident3 Ų369.1 Ų69.12%0.01836%0.362CS..BIsolated β-bridgetrans-117.5118.6176.1-176.50000106.6Q411 E415 V416 Y417 E447 Y576Q411-V413 HydrophobicContact CG-CG2 3.77Å; Q411-V413 PolarHBondContact O-N 2.83Å; V413-E415 PolarHBondContact O-N 2.87Å; V413-V416 HydrophobicContact CB-CB 3.97Å; V413-V416 HydrophobicContact CG1-CB 3.84Å; V413-V416 HydrophobicContact CG1-CG2 3.87Å; V413-V416 PolarHBondContact O-N 2.71Å; V413-Y417 PolarHBondContact N-O 2.88Å; V413-Y417 PolarHBondContact O-N 3.49Å; V413-Y417 VanDerWaalsContact O-O 3.13Å; V413-E447 CarbonylContact C-O 3.58Å; V413-E447 VanDerWaalsContact CA-O 3.31Å; V413-E447 WeakPolarHBondContact CA-O 3.37Å; V413-E447 HydrophobicContact CG2-CB 4.4Å; V413-Y576 HydrophobicContact CG1-CD2 4.22Å; V413-Y576 HydrophobicContact CG1-CE2 3.82Å; V413-Y576 HydrophobicContact CG2-CD1 4.24Å; V413-Y576 HydrophobicContact CG2-CD2 4.42Å; V413-Y576 HydrophobicContact CG2-CE1 4.16Å; V413-Y576 HydrophobicContact CG2-CE2 4.34Å; V413-Y576 HydrophobicContact CG2-CG 4.37Å
414A85.6Confident79Confident18 Ų1870.7 Ų70.715%0.14937%0.373CS..THydrogen-bonded Turntrans-52.3135.9178.900000110V416 E447 Y448A414-V416 PolarHBondContact O-N 3.34Å; A414-E447 PolarHBondContact N-O 3.48Å; A414-Y448 HydrophobicContact CB-CD1 3.51Å; A414-Y448 HydrophobicContact CB-CE1 3.48Å; A414-Y448 VanDerWaalsContact CB-CE1 3.48Å; A414-Y448 HydrophobicContact CB-CG 4.18Å
415E81.3Confident77.5Confident91 Ų9178.2 Ų78.243%0.42540%0.404SS..THydrogen-bonded Turntrans65.5-4.6-178.3-56.8174.9176.800116.5V413 P424 S427V413-E415 PolarHBondContact O-N 2.87Å; E415-P424 HydrophobicContact CG-CG 3.83Å; E415-P424 VanDerWaalsContact OE1-CD 3.26Å; E415-P424 WeakPolarHBondContact OE1-CD 3.34Å; E415-P424 VanDerWaalsContact OE1-CG 3.27Å; E415-P424 WeakPolarHBondContact OE1-CG 3.44Å; E415-S427 PolarHBondContact OE1-OG 3.12Å
416V83.9Confident76.8Confident27 Ų2771.5 Ų71.516%0.16438%0.378CS..THydrogen-bonded Turntrans-117.5-45.8-176.2-1800000111.7V413 A414 I562 L563V413-V416 HydrophobicContact CB-CB 3.97Å; V413-V416 HydrophobicContact CG1-CB 3.84Å; V413-V416 HydrophobicContact CG1-CG2 3.87Å; V413-V416 PolarHBondContact O-N 2.71Å; A414-V416 PolarHBondContact O-N 3.34Å; V416-I562 HydrophobicContact CG1-CB 4.31Å; V416-I562 HydrophobicContact CG1-CD1 4.04Å; V416-I562 HydrophobicContact CG1-CG1 4.12Å; V416-L563 HydrophobicContact CG1-CB 3.92Å; V416-L563 HydrophobicContact CG2-CD1 4.4Å; V416-L563 HydrophobicContact CG2-CD2 4.25Å
417Y84.4Confident76.2Confident68 Ų6870.9 Ų70.927%0.26738%0.376SS..BIsolated β-bridgetrans-158.2132.8-176.5-169.8-92.4000113.9T410 K412 V413 I562 N578T410-Y417 VanDerWaalsContact CB-CE1 3.44Å; T410-Y417 HydrophobicContact CG2-CD1 3.39Å; T410-Y417 HydrophobicContact CG2-CD2 4.39Å; T410-Y417 HydrophobicContact CG2-CE1 3.37Å; T410-Y417 HydrophobicContact CG2-CE2 4.37Å; T410-Y417 HydrophobicContact CG2-CG 3.92Å; K412-Y417 WeakPolarHBondContact CA-O 3.28Å; V413-Y417 PolarHBondContact N-O 2.88Å; V413-Y417 PolarHBondContact O-N 3.49Å; V413-Y417 VanDerWaalsContact O-O 3.13Å; Y417-I562 HydrophobicContact CD2-CD1 4.48Å; Y417-I562 HydrophobicContact CG-CD1 4.24Å; Y417-N578 WeakPolarHBondContact CE2-ND2 3.42Å; Y417-N578 PolarHBondContact OH-ND2 3.15Å
418P76.9Confident75.6Confident66 Ų6674.4 Ų74.443%0.42940%0.404SS..SBendcis-67.3146.3-728.6-33.9000110.8R420P418-R420 PolarHBondContact O-N 3.06Å
419D68.3Low75Confident137 Ų13776.4 Ų76.473%0.73343%0.425SS*.  trans-65.783.6178.3-165.63.2000109.6
420R59.1Low74.5Confident190 Ų19072.5 Ų72.572%0.71740%0.398SS*.  trans-87.7124.6167.1-72.8-178.7171.8-167.8-3.2104.5P418 S422P418-R420 PolarHBondContact O-N 3.06Å; R420-S422 WeakPolarHBondContact CB-OG 3.32Å; R420-S422 PolarHBondContact O-N 2.92Å
421N50.6Low74Confident171 Ų17173.8 Ų73.891%0.91441%0.413SS*.SBendtrans-54.922.3171.1-87.5-9.8000115.1
422S50.7Low73.7Confident76 Ų7673 Ų7353%0.53141%0.412SS..  trans-112.188.4176.956.60000108.5R420 P424R420-S422 WeakPolarHBondContact CB-OG 3.32Å; R420-S422 PolarHBondContact O-N 2.92Å; S422-P424 VanDerWaalsContact O-CD 3.28Å; S422-P424 WeakPolarHBondContact O-CD 3.45Å
423S51Low73.2Confident98 Ų9868.7 Ų68.769%0.68540%0.398SS*.  trans-54.4117.7153.7-45.20000106.8K425S423-K425 VanDerWaalsContact C-N 3.34Å; S423-K425 PolarHBondContact O-N 3.03Å
424P55.3Low72.5Confident35 Ų3572.5 Ų72.523%0.22742%0.422CS..  trans-70104.7166.633.5-30.3000105.1E415 S422 C426E415-P424 HydrophobicContact CG-CG 3.83Å; E415-P424 VanDerWaalsContact OE1-CD 3.26Å; E415-P424 WeakPolarHBondContact OE1-CD 3.34Å; E415-P424 VanDerWaalsContact OE1-CG 3.27Å; E415-P424 WeakPolarHBondContact OE1-CG 3.44Å; S422-P424 VanDerWaalsContact O-CD 3.28Å; S422-P424 WeakPolarHBondContact O-CD 3.45Å; P424-C426 VanDerWaalsContact CB-SG 3.54Å; P424-C426 PolarHBondContact O-N 3.12Å; P424-C426 PolarHBondContact O-SG 3.15Å
425K63.2Low72Confident185 Ų18574.2 Ų74.280%0.80443%0.429SS*.THydrogen-bonded Turntrans-54.6-0.9176.2-60.8175.2-179.8177.10113.6S423 A428S423-K425 VanDerWaalsContact C-N 3.34Å; S423-K425 PolarHBondContact O-N 3.03Å; K425-A428 WeakPolarHBondContact O-CB 3.17Å; K425-A428 PolarHBondContact O-N 3.1Å
426C80.9Confident71.9Confident22 Ų2270.2 Ų70.215%0.14941%0.411CS..THydrogen-bonded Turntrans-65.5-35.5-178.158.20000113.4P424 R474 C475 Y477P424-C426 VanDerWaalsContact CB-SG 3.54Å; P424-C426 PolarHBondContact O-N 3.12Å; P424-C426 PolarHBondContact O-SG 3.15Å; C426-R474 HydrophobicContact CB-CB 4.42Å; C426-C475 HydrophobicContact CB-CB 4.14Å; C426-C475 WeakPolarHBondContact CB-SG 3.32Å; C426-C475 WeakPolarHBondContact SG-CA 3.42Å; C426-C475 WeakPolarHBondContact SG-CB 3.44Å; C426-C475 CovalentContact SG-SG 2.03Å; C426-C475 PolarHBondContact SG-SG 2.65Å; C426-Y477 WeakPolarHBondContact CB-OH 3.19Å
427S81.4Confident72.1Confident17 Ų1769.7 Ų69.712%0.11941%0.407CS..SBendtrans-91.1-9.7-179.362.30000112.9E415 G429 C430 H453E415-S427 PolarHBondContact OE1-OG 3.12Å; S427-G429 PolarHBondContact O-N 2.88Å; S427-G429 VanDerWaalsContact O-N 3.11Å; S427-C430 WeakPolarHBondContact O-CB 3.37Å; S427-C430 PolarHBondContact O-N 2.83Å; S427-C430 PolarHBondContact O-SG 3.18Å; S427-H453 WeakPolarHBondContact CB-O 3.3Å
428A78.1Confident72.3Confident83 Ų8366.9 Ų66.969%0.68640%0.396SS*.G310 helixtrans-60-27.1-175.900000113.5K425 C430K425-A428 WeakPolarHBondContact O-CB 3.17Å; K425-A428 PolarHBondContact O-N 3.1Å; A428-C430 VanDerWaalsContact C-N 3.33Å
429G79.4Confident73Confident44 Ų4463.8 Ų63.845%0.45438%0.376SS..G310 helixtrans-85.84.7176.100000115.1S427S427-G429 PolarHBondContact O-N 2.88Å; S427-G429 VanDerWaalsContact O-N 3.11Å
430C80.7Confident74.1Confident5 Ų557.2 Ų57.23%0.03434%0.341CS..G310 helixtrans-98.5-9.1-172.2-58.80000114.6C133 F134 S427 A428 C432C133-C430 HydrophobicContact CB-CB 3.68Å; C133-C430 WeakPolarHBondContact CB-SG 3.29Å; C133-C430 WeakPolarHBondContact SG-CB 3.36Å; C133-C430 CovalentContact SG-SG 2.02Å; C133-C430 PolarHBondContact SG-SG 3.33Å; F134-C430 CarbonylContact O-C 3.54Å; F134-C430 VanDerWaalsContact O-C 3.26Å; F134-C430 VanDerWaalsContact O-CA 3.28Å; F134-C430 WeakPolarHBondContact O-CA 3.32Å; F134-C430 VanDerWaalsContact O-O 3.13Å; S427-C430 WeakPolarHBondContact O-CB 3.37Å; S427-C430 PolarHBondContact O-N 2.83Å; S427-C430 PolarHBondContact O-SG 3.18Å; A428-C430 VanDerWaalsContact C-N 3.33Å; C430-C432 WeakPolarHBondContact CB-SG 3.05Å; C430-C432 PolarHBondContact O-N 3.27Å
431G79.4Confident75.6Confident37 Ų3749.3 Ų49.338%0.38132%0.315SS..  trans5632.9-179.800000114.4
432C80.3Confident77.6Confident29 Ų2941.3 Ų41.320%0.19627%0.273CS..  trans-65.2132.1-171.8-570000112.2C430 C452C430-C432 WeakPolarHBondContact CB-SG 3.05Å; C430-C432 PolarHBondContact O-N 3.27Å; C432-C452 WeakPolarHBondContact CA-SG 2.96Å; C432-C452 HydrophobicContact CB-CB 3.95Å; C432-C452 WeakPolarHBondContact CB-SG 3.4Å; C432-C452 WeakPolarHBondContact SG-CB 3.37Å; C432-C452 PolarHBondContact SG-O 2.99Å; C432-C452 CovalentContact SG-SG 2.04Å; C432-C452 PolarHBondContact SG-SG 3.28Å
433P77.3Confident79.6Confident41 Ų4140.1 Ų40.127%0.26626%0.264SS..  trans-60.1137.5175.9-22.932.3000111.8D435 A436P433-D435 WeakPolarHBondContact CB-OD1 3.47Å; P433-D435 PolarHBondContact O-N 3.42Å; P433-A436 HydrophobicContact CB-CB 4.18Å; P433-A436 VanDerWaalsContact O-CB 3.24Å; P433-A436 WeakPolarHBondContact O-CB 3.31Å; P433-A436 PolarHBondContact O-N 2.95Å; P433-A436 VanDerWaalsContact O-N 3.1Å
434P74.6Confident81.3Confident83 Ų8338.2 Ų38.254%0.53925%0.246SC..THydrogen-bonded Turntrans-69.3-17.3-177.529-35.7000113.2R449P434-R449 PolarHBondContact O-NH1 3.21Å; P434-R449 PolarHBondContact O-NH2 3Å
435D74.3Confident82.9Confident54 Ų5438.9 Ų38.929%0.28926%0.26SS..THydrogen-bonded Turntrans-91.3-9.7175.162.6-31.5000113.1P433 F437 E566P433-D435 WeakPolarHBondContact CB-OD1 3.47Å; P433-D435 PolarHBondContact O-N 3.42Å; D435-F437 PolarHBondContact O-N 3.46Å; D435-E566 WeakPolarHBondContact CB-O 3.47Å
436A80.8Confident84.1Confident6 Ų633.4 Ų33.45%0.0524%0.237CC..  trans-59.7122.6-177.100000112.1T119 P433 R449T119-A436 HydrophobicContact CG2-CB 3.8Å; P433-A436 HydrophobicContact CB-CB 4.18Å; P433-A436 VanDerWaalsContact O-CB 3.24Å; P433-A436 WeakPolarHBondContact O-CB 3.31Å; P433-A436 PolarHBondContact O-N 2.95Å; P433-A436 VanDerWaalsContact O-N 3.1Å; A436-R449 WeakPolarHBondContact O-CD 3.49Å; A436-R449 PolarHBondContact O-NE 3.31Å
437F87.3Confident84.6Confident17 Ų1732.4 Ų32.48%0.07523%0.23CC..  trans-140.6109.1179.6-170.2-105.6000110.8T119 L236 R237 D435 P439 R449 L575 Y576T119-F437 VanDerWaalsContact CB-O 3.29Å; T119-F437 WeakPolarHBondContact CB-O 3.42Å; T119-F437 PolarHBondContact OG1-N 3.21Å; T119-F437 PolarHBondContact OG1-O 3.22Å; L236-F437 HydrophobicContact CB-CE1 3.99Å; L236-F437 HydrophobicContact CB-CZ 4.26Å; L236-F437 HydrophobicContact CD1-CZ 3.97Å; R237-F437 WeakPolarHBondContact CD-O 3.3Å; R237-F437 HydrophobicContact CG-CD1 4.02Å; R237-F437 HydrophobicContact CG-CE1 4.26Å; D435-F437 PolarHBondContact O-N 3.46Å; F437-P439 HydrophobicContact CE1-CG 4.42Å; F437-P439 HydrophobicContact CZ-CG 4.36Å; F437-R449 HydrophobicContact CD2-CG 3.83Å; F437-R449 HydrophobicContact CE2-CG 4.44Å; F437-L575 HydrophobicContact CB-CD1 4.43Å; F437-L575 HydrophobicContact CD1-CD2 3.99Å; F437-L575 HydrophobicContact CD2-CB 4.37Å; F437-L575 HydrophobicContact CD2-CD1 3.63Å; F437-L575 HydrophobicContact CD2-CD2 4.26Å; F437-L575 HydrophobicContact CD2-CG 4.3Å; F437-L575 HydrophobicContact CE1-CD2 3.97Å; F437-L575 HydrophobicContact CE2-CB 3.86Å; F437-L575 HydrophobicContact CE2-CD1 4Å; F437-L575 HydrophobicContact CE2-CD2 4.25Å; F437-L575 HydrophobicContact CE2-CG 4.25Å; F437-L575 HydrophobicContact CG-CD1 4.01Å; F437-L575 HydrophobicContact CG-CD2 4.13Å; F437-L575 HydrophobicContact CZ-CB 4.08Å; F437-L575 HydrophobicContact CZ-CD2 4.11Å; F437-Y576 HydrophobicContact CE2-CD2 4.49Å; F437-Y576 AromaticContact CE2-CE2 3.79Å; F437-Y576 HydrophobicContact CE2-CE2 3.79Å; F437-Y576 HydrophobicContact CZ-CE2 4.5Å
438N88.8Confident85Confident8 Ų832 Ų324%0.04323%0.226CC..  trans-154.278.6175.9-176.84.8000107.9D120 R237 I440 R449 S450 P451D120-N438 PolarHBondContact OD1-ND2 3.34Å; D120-N438 PolarHBondContact OD2-ND2 3.33Å; R237-N438 PolarHBondContact NH1-ND2 3.49Å; R237-N438 PolarHBondContact NH1-OD1 3.02Å; R237-N438 PolarHBondContact NH2-OD1 3.32Å; R237-N438 VanDerWaalsContact NH2-OD1 3.15Å; N438-I440 PolarHBondContact O-N 3.46Å; N438-R449 CarbonylContact C-O 3.55Å; N438-R449 VanDerWaalsContact C-O 3.3Å; N438-R449 PolarHBondContact N-O 3.41Å; N438-S450 VanDerWaalsContact O-CA 3.25Å; N438-S450 WeakPolarHBondContact O-CA 3.49Å; N438-P451 WeakPolarHBondContact O-CD 3.41Å
439P90.8Very high85.5Confident1 Ų129.5 Ų29.51%0.00620%0.199CC..  trans-58.7137.1-168.125.8-35.9000112L236 F437 Y448 G486 T487L236-P439 HydrophobicContact CB-CG 4.41Å; L236-P439 HydrophobicContact CD1-CG 4.16Å; L236-P439 HydrophobicContact CG-CG 4.5Å; F437-P439 HydrophobicContact CE1-CG 4.42Å; F437-P439 HydrophobicContact CZ-CG 4.36Å; P439-Y448 WeakPolarHBondContact CA-O 3.48Å; P439-G486 CarbonylContact C-O 3.48Å; P439-G486 CarbonylContact O-C 3.42Å; P439-G486 VanDerWaalsContact O-CA 3.26Å; P439-G486 WeakPolarHBondContact O-CA 3.32Å; P439-G486 PolarHBondContact O-N 3.26Å; P439-T487 HydrophobicContact CB-CG2 4.35Å; P439-T487 HydrophobicContact CG-CG2 4.42Å
440I91.4Very high86Confident0 Ų027.6 Ų27.60%018%0.179CC..EExtended strand (participates in β ladder)trans-131.5149.8175.858.9167.3000110.5N438 E447 Y448 P451 A454 F470 A483 Q484 G486N438-I440 PolarHBondContact O-N 3.46Å; I440-E447 WeakPolarHBondContact O-CA 3.49Å; I440-Y448 PolarHBondContact N-O 3.34Å; I440-Y448 VanDerWaalsContact N-O 3.08Å; I440-Y448 PolarHBondContact O-N 3.06Å; I440-P451 HydrophobicContact CD1-CB 4.37Å; I440-P451 HydrophobicContact CD1-CG 4.47Å; I440-P451 HydrophobicContact CG2-CG 3.94Å; I440-A454 HydrophobicContact CD1-CB 3.54Å; I440-F470 HydrophobicContact CG2-CD2 3.79Å; I440-F470 HydrophobicContact CG2-CE2 3.64Å; I440-F470 HydrophobicContact CG2-CZ 4.48Å; I440-A483 HydrophobicContact CB-CB 4.3Å; I440-A483 HydrophobicContact CD1-CB 3.67Å; I440-A483 HydrophobicContact CG1-CB 4.31Å; I440-Q484 CarbonylContact C-O 3.59Å; I440-Q484 WeakPolarHBondContact CA-O 3.46Å; I440-Q484 WeakPolarHBondContact CB-O 3.48Å; I440-G486 CarbonylContact C-O 3.54Å; I440-G486 WeakPolarHBondContact CA-O 3.34Å; I440-G486 PolarHBondContact N-O 3.26Å
441C92.1Very high86.4Confident24 Ų2427.5 Ų27.516%0.16218%0.178CC..EExtended strand (participates in β ladder)trans-100.5116.1174.1-172.10000110.5A483 Q484 G486 C488C441-A483 CarbonylContact O-C 3.43Å; C441-A483 WeakPolarHBondContact O-CA 3.29Å; C441-A483 WeakPolarHBondContact O-CB 3.28Å; C441-Q484 PolarHBondContact N-O 3.02Å; C441-Q484 PolarHBondContact O-N 3.37Å; C441-G486 PolarHBondContact N-O 3.48Å; C441-C488 WeakPolarHBondContact CA-SG 3.44Å; C441-C488 HydrophobicContact CB-CB 3.9Å; C441-C488 WeakPolarHBondContact CB-SG 3.49Å; C441-C488 WeakPolarHBondContact SG-CA 3.21Å; C441-C488 WeakPolarHBondContact SG-CB 3.17Å; C441-C488 CovalentContact SG-SG 2.04Å; C441-C488 PolarHBondContact SG-SG 3.12Å
442G92.4Very high86.8Confident3 Ų326.1 Ų26.13%0.03116%0.162CC..EExtended strand (participates in β ladder)trans-69151.5173.200000111.6N444 G445 E446G442-N444 WeakPolarHBondContact CA-OD1 3.41Å; G442-N444 PolarHBondContact O-N 3.45Å; G442-N444 VanDerWaalsContact O-N 3.15Å; G442-G445 PolarHBondContact O-N 3.28Å; G442-E446 PolarHBondContact N-O 2.81Å
443S91.7Very high87.1Confident51 Ų5126 Ų2636%0.35716%0.159SC..THydrogen-bonded Turntrans-61.5-17.7173.951.60000113.6G445 I476 D478 S480 S482S443-G445 PolarHBondContact O-N 3.16Å; S443-I476 WeakPolarHBondContact OG-CG2 3.18Å; S443-D478 WeakPolarHBondContact CB-OD2 3.1Å; S443-D478 PolarHBondContact OG-OD1 3.04Å; S443-D478 PolarHBondContact OG-OD2 2.89Å; S443-S480 WeakPolarHBondContact CB-OG 3.22Å; S443-S480 PolarHBondContact OG-OG 3.11Å; S443-S482 WeakPolarHBondContact CB-O 3.34Å; S443-S482 PolarHBondContact N-O 3Å; S443-S482 PolarHBondContact OG-O 3.1Å
444N88.2Confident87.7Confident57 Ų5724 Ų2431%0.30515%0.146SC..THydrogen-bonded Turntrans-74.4-2.816865.4-21.7000114.5G442 E446 Y448 I476 D478G442-N444 WeakPolarHBondContact CA-OD1 3.41Å; G442-N444 PolarHBondContact O-N 3.45Å; G442-N444 VanDerWaalsContact O-N 3.15Å; N444-E446 VanDerWaalsContact C-N 3.31Å; N444-E446 PolarHBondContact ND2-OE2 3.42Å; N444-E446 PolarHBondContact OD1-N 2.9Å; N444-Y448 PolarHBondContact ND2-OH 2.76Å; N444-I476 HydrophobicContact CB-CG2 4.26Å; N444-D478 HydrophobicContact CB-CB 4.39Å
445G87.8Confident88.4Confident50 Ų5020 Ų2052%0.51512%0.12SC..SBendtrans74.917-177.500000114.3G442 S443G442-G445 PolarHBondContact O-N 3.28Å; S443-G445 PolarHBondContact O-N 3.16Å
446E89Confident89.2Confident69 Ų6917.5 Ų17.532%0.32211%0.107SC..  trans-104.2140.2172.4-61.3-168.9152.200110.8G442 N444 Y448G442-E446 PolarHBondContact N-O 2.81Å; N444-E446 VanDerWaalsContact C-N 3.31Å; N444-E446 PolarHBondContact ND2-OE2 3.42Å; N444-E446 PolarHBondContact OD1-N 2.9Å; E446-Y448 HydrophobicContact CB-CE2 4.19Å; E446-Y448 WeakPolarHBondContact O-CD2 3.23Å; E446-Y448 WeakPolarHBondContact O-CE2 3.35Å
447E91.1Very high89.5Confident2 Ų220.3 Ų20.31%0.00912%0.121CC..EExtended strand (participates in β ladder)trans-89.4138.1179-172168.114300110.6K412 V413 A414 I440 T487 C488 Y576K412-E447 PolarHBondContact O-N 2.96Å; K412-E447 VanDerWaalsContact O-N 3.12Å; V413-E447 CarbonylContact C-O 3.58Å; V413-E447 VanDerWaalsContact CA-O 3.31Å; V413-E447 WeakPolarHBondContact CA-O 3.37Å; V413-E447 HydrophobicContact CG2-CB 4.4Å; A414-E447 PolarHBondContact N-O 3.48Å; I440-E447 WeakPolarHBondContact O-CA 3.49Å; E447-T487 WeakPolarHBondContact OE1-CG2 3.27Å; E447-T487 WeakPolarHBondContact OE2-CA 3.37Å; E447-T487 VanDerWaalsContact OE2-CB 3.26Å; E447-T487 WeakPolarHBondContact OE2-CB 3.16Å; E447-C488 PolarHBondContact OE2-N 3.22Å; E447-Y576 WeakPolarHBondContact OE1-CE1 3.35Å; E447-Y576 PolarHBondContact OE1-OH 2.81Å
448Y90.1Very high89.4Confident9 Ų923.2 Ų23.24%0.03514%0.137CC..EExtended strand (participates in β ladder)trans-118.2144.1177-61.1-102.6000109.9A414 P439 I440 N444 E446 S450 A454 C475 I476A414-Y448 HydrophobicContact CB-CD1 3.51Å; A414-Y448 HydrophobicContact CB-CE1 3.48Å; A414-Y448 VanDerWaalsContact CB-CE1 3.48Å; A414-Y448 HydrophobicContact CB-CG 4.18Å; P439-Y448 WeakPolarHBondContact CA-O 3.48Å; I440-Y448 PolarHBondContact N-O 3.34Å; I440-Y448 VanDerWaalsContact N-O 3.08Å; I440-Y448 PolarHBondContact O-N 3.06Å; N444-Y448 PolarHBondContact ND2-OH 2.76Å; E446-Y448 HydrophobicContact CB-CE2 4.19Å; E446-Y448 WeakPolarHBondContact O-CD2 3.23Å; E446-Y448 WeakPolarHBondContact O-CE2 3.35Å; Y448-S450 VanDerWaalsContact C-N 3.25Å; Y448-S450 PolarHBondContact O-N 3.28Å; Y448-A454 HydrophobicContact CD1-CB 3.78Å; Y448-A454 HydrophobicContact CD2-CB 4.23Å; Y448-A454 HydrophobicContact CE1-CB 4.38Å; Y448-A454 HydrophobicContact CG-CB 3.7Å; Y448-C475 HydrophobicContact CE1-CB 3.87Å; Y448-C475 PolarHBondContact OH-O 2.8Å; Y448-I476 HydrophobicContact CE2-CD1 4.29Å; Y448-I476 HydrophobicContact CE2-CG1 3.95Å
449R88.4Confident89.3Confident30 Ų3026.5 Ų26.511%0.11315%0.151CC..SBendtrans-60-33.3-176.7-171.6-175.5172.7176.4-2113.7P434 A436 F437 N438 L563P434-R449 PolarHBondContact O-NH1 3.21Å; P434-R449 PolarHBondContact O-NH2 3Å; A436-R449 WeakPolarHBondContact O-CD 3.49Å; A436-R449 PolarHBondContact O-NE 3.31Å; F437-R449 HydrophobicContact CD2-CG 3.83Å; F437-R449 HydrophobicContact CE2-CG 4.44Å; N438-R449 CarbonylContact C-O 3.55Å; N438-R449 VanDerWaalsContact C-O 3.3Å; N438-R449 PolarHBondContact N-O 3.41Å; R449-L563 HydrophobicContact CG-CD2 4.28Å
450S88.7Confident89.1Confident3 Ų329.7 Ų29.72%0.02117%0.17CC..  trans-158.8163.1178.166.60000111.7N438 Y448 C452 H453 A454N438-S450 VanDerWaalsContact O-CA 3.25Å; N438-S450 WeakPolarHBondContact O-CA 3.49Å; Y448-S450 VanDerWaalsContact C-N 3.25Å; Y448-S450 PolarHBondContact O-N 3.28Å; S450-C452 VanDerWaalsContact C-N 3.26Å; S450-C452 PolarHBondContact O-N 3.16Å; S450-H453 PolarHBondContact O-N 2.97Å; S450-H453 VanDerWaalsContact O-N 3.15Å; S450-H453 PolarHBondContact OG-N 2.97Å; S450-H453 PolarHBondContact OG-ND1 3.2Å; S450-A454 PolarHBondContact O-N 3.1Å
451P89.3Confident88.6Confident4 Ų433 Ų333%0.02619%0.186CC..THydrogen-bonded Turntrans-55.9-38.3171.2-23.633.4000113.4L132 N438 I440 A454 G455 C456 F470L132-P451 HydrophobicContact CD2-CB 4Å; N438-P451 WeakPolarHBondContact O-CD 3.41Å; I440-P451 HydrophobicContact CD1-CB 4.37Å; I440-P451 HydrophobicContact CD1-CG 4.47Å; I440-P451 HydrophobicContact CG2-CG 3.94Å; P451-A454 PolarHBondContact O-N 3.29Å; P451-G455 PolarHBondContact O-N 3.03Å; P451-C456 HydrophobicContact CB-CB 4.3Å; P451-C456 WeakPolarHBondContact O-CB 3.41Å; P451-C456 PolarHBondContact O-N 3.47Å; P451-F470 HydrophobicContact CB-CD1 3.79Å; P451-F470 HydrophobicContact CB-CE1 3.8Å; P451-F470 HydrophobicContact CB-CG 4.28Å; P451-F470 HydrophobicContact CB-CZ 4.32Å; P451-F470 HydrophobicContact CG-CD1 3.95Å; P451-F470 HydrophobicContact CG-CD2 4.4Å; P451-F470 HydrophobicContact CG-CE1 3.51Å; P451-F470 HydrophobicContact CG-CE2 4.02Å; P451-F470 HydrophobicContact CG-CG 4.36Å; P451-F470 HydrophobicContact CG-CZ 3.55Å
452C87.8Confident87.9Confident7 Ų736.1 Ų36.15%0.04720%0.202CC..THydrogen-bonded Turntrans-61.6-46.9175.1-171.90000112.1G131 C432 S450 A454 G455G131-C452 WeakPolarHBondContact O-CB 3.48Å; G131-C452 PolarHBondContact O-N 2.97Å; G131-C452 VanDerWaalsContact O-N 3.13Å; C432-C452 WeakPolarHBondContact CA-SG 2.96Å; C432-C452 HydrophobicContact CB-CB 3.95Å; C432-C452 WeakPolarHBondContact CB-SG 3.4Å; C432-C452 WeakPolarHBondContact SG-CB 3.37Å; C432-C452 PolarHBondContact SG-O 2.99Å; C432-C452 CovalentContact SG-SG 2.04Å; C432-C452 PolarHBondContact SG-SG 3.28Å; S450-C452 VanDerWaalsContact C-N 3.26Å; S450-C452 PolarHBondContact O-N 3.16Å; C452-A454 PolarHBondContact O-N 3.44Å; C452-G455 WeakPolarHBondContact O-CA 3.49Å; C452-G455 PolarHBondContact O-N 3.41Å
453H87.7Confident87.1Confident26 Ų2640.6 Ų40.612%0.1224%0.238CC..THydrogen-bonded Turntrans-68.1-24.3-179.9-72.473.4000112.3S427 S450 G455S427-H453 WeakPolarHBondContact CB-O 3.3Å; S450-H453 PolarHBondContact O-N 2.97Å; S450-H453 VanDerWaalsContact O-N 3.15Å; S450-H453 PolarHBondContact OG-N 2.97Å; S450-H453 PolarHBondContact OG-ND1 3.2Å; H453-G455 VanDerWaalsContact C-N 3.26Å
454A89.9Confident85.9Confident0 Ų044 Ų440%025%0.252CS..THydrogen-bonded Turntrans-79.9-4.4168.800000113.8I440 Y448 S450 P451 C452 C456 C473 R474 C475I440-A454 HydrophobicContact CD1-CB 3.54Å; Y448-A454 HydrophobicContact CD1-CB 3.78Å; Y448-A454 HydrophobicContact CD2-CB 4.23Å; Y448-A454 HydrophobicContact CE1-CB 4.38Å; Y448-A454 HydrophobicContact CG-CB 3.7Å; S450-A454 PolarHBondContact O-N 3.1Å; P451-A454 PolarHBondContact O-N 3.29Å; C452-A454 PolarHBondContact O-N 3.44Å; A454-C456 VanDerWaalsContact C-N 3.34Å; A454-C473 CarbonylContact O-C 3.54Å; A454-C473 WeakPolarHBondContact O-CB 3.09Å; A454-R474 PolarHBondContact O-N 2.96Å; A454-C475 VanDerWaalsContact O-CB 3.26Å; A454-C475 WeakPolarHBondContact O-CB 3.07Å; A454-C475 PolarHBondContact O-N 2.83Å
455G89.5Confident85Confident0 Ų046.8 Ų46.80%027%0.267CS..THydrogen-bonded Turntrans72.523.5-179.200000114P451 C452 H453 C473 R474P451-G455 PolarHBondContact O-N 3.03Å; C452-G455 WeakPolarHBondContact O-CA 3.49Å; C452-G455 PolarHBondContact O-N 3.41Å; H453-G455 VanDerWaalsContact C-N 3.26Å; G455-C473 WeakPolarHBondContact O-CA 3.43Å; G455-R474 PolarHBondContact O-N 3.3Å; G455-R474 VanDerWaalsContact O-N 3.1Å
456C90Very high84.3Confident0 Ų048.6 Ų48.60%026%0.261CS..  trans-71.7133-177.7-57.40000111.6L132 C133 P451 A454 F470 C473L132-C456 WeakPolarHBondContact CB-O 3.32Å; L132-C456 HydrophobicContact CD2-CB 4.02Å; C133-C456 WeakPolarHBondContact CB-O 3.45Å; C133-C456 PolarHBondContact N-O 3.06Å; P451-C456 HydrophobicContact CB-CB 4.3Å; P451-C456 WeakPolarHBondContact O-CB 3.41Å; P451-C456 PolarHBondContact O-N 3.47Å; A454-C456 VanDerWaalsContact C-N 3.34Å; C456-F470 HydrophobicContact CB-CB 4.12Å; C456-C473 VanDerWaalsContact CA-SG 3.59Å; C456-C473 HydrophobicContact CB-CB 4.08Å; C456-C473 WeakPolarHBondContact CB-SG 3.44Å; C456-C473 WeakPolarHBondContact SG-CB 3.49Å; C456-C473 CovalentContact SG-SG 2.04Å; C456-C473 PolarHBondContact SG-SG 3.28Å
457L87.9Confident83.6Confident66 Ų6646.9 Ų46.935%0.34626%0.256SS..  trans-99.3-24.8-178.4-63.3173.1000113C133 T471 N472C133-L457 HydrophobicContact CB-CD2 4.36Å; C133-L457 WeakPolarHBondContact O-CD2 3.44Å; L457-T471 PolarHBondContact N-O 3.3Å; L457-N472 HydrophobicContact CB-CB 4.08Å; L457-N472 HydrophobicContact CD1-CB 4.21Å; L457-N472 HydrophobicContact CG-CB 4.44Å; L457-N472 PolarHBondContact N-O 3.12Å
458N85.3Confident83.2Confident78 Ų7849.7 Ų49.742%0.41727%0.273SS..EExtended strand (participates in β ladder)trans-131.5146.9-173.9-68-27.1000111F470 T471 N472N458-F470 WeakPolarHBondContact O-CA 3.48Å; N458-T471 WeakPolarHBondContact CB-OG1 2.95Å; N458-T471 PolarHBondContact N-O 2.92Å; N458-T471 PolarHBondContact O-N 2.84Å; N458-N472 PolarHBondContact ND2-ND2 3.32Å
459K86.8Confident83.2Confident77 Ų7751.5 Ų51.534%0.33528%0.284SS..EExtended strand (participates in β ladder)trans-120.4135.3168.466.3-179-176.8175.10109.7L132 M461 F470L132-K459 HydrophobicContact CD1-CB 4.29Å; L132-K459 HydrophobicContact CD1-CD 4.48Å; L132-K459 HydrophobicContact CD1-CG 4.17Å; L132-K459 HydrophobicContact CD2-CB 4.42Å; K459-M461 HydrophobicContact CD-SD 3.84Å; K459-M461 HydrophobicContact CG-SD 3.98Å; K459-F470 HydrophobicContact CB-CD1 3.81Å; K459-F470 HydrophobicContact CB-CE1 3.77Å
460V85.2Confident83.3Confident67 Ų6750.4 Ų50.441%0.40628%0.28SS..EExtended strand (participates in β ladder)trans-99.1131.6174.6-175.80000107.5P467 T468 N469 T471V460-P467 CarbonylContact O-C 3.26Å; V460-P467 WeakPolarHBondContact O-CA 3.36Å; V460-T468 PolarHBondContact O-N 2.94Å; V460-T468 PolarHBondContact O-OG1 2.85Å; V460-N469 HydrophobicContact CB-CB 4.27Å; V460-N469 HydrophobicContact CG2-CB 4.43Å; V460-N469 PolarHBondContact N-O 2.84Å; V460-T471 HydrophobicContact CG2-CG2 4.28Å
461M81.3Confident83.3Confident69 Ų6952 Ų5234%0.3429%0.289SS..EExtended strand (participates in β ladder)trans-112.4146.9-176.9-51.3-63.2-74.600110K459 N465 K466 P467K459-M461 HydrophobicContact CD-SD 3.84Å; K459-M461 HydrophobicContact CG-SD 3.98Å; M461-N465 VanDerWaalsContact CE-C 3.49Å; M461-N465 WeakPolarHBondContact CE-O 3.29Å; M461-K466 CarbonylContact C-O 3.57Å; M461-K466 VanDerWaalsContact CA-O 3.27Å; M461-K466 WeakPolarHBondContact CA-O 3.3Å; M461-P467 HydrophobicContact SD-CB 3.96Å
462D78.8Confident83.4Confident91 Ų9156.2 Ų56.249%0.48731%0.311SS..  trans-80.9175.3170.5-151-10.7000112.1D464 N465 K466 T468D462-D464 PolarHBondContact O-N 3.16Å; D462-N465 PolarHBondContact O-N 2.92Å; D462-K466 PolarHBondContact N-O 3.41Å; D462-T468 HydrophobicContact CB-CG2 3.62Å
463A74.1Confident83.5Confident96 Ų9656.1 Ų56.179%0.79331%0.311SS*.THydrogen-bonded Turntrans-55.4-28173.400000113.6N465A463-N465 VanDerWaalsContact C-N 3.3Å; A463-N465 PolarHBondContact O-N 3.3Å
464D67.4Low83.6Confident124 Ų12460.4 Ų60.466%0.66333%0.326SS*.THydrogen-bonded Turntrans-88.816175.3-68.4-35.3000113.3D462 K466D462-D464 PolarHBondContact O-N 3.16Å; D464-K466 HydrophobicContact CB-CG 4.46Å; D464-K466 PolarHBondContact O-N 2.82Å
465N68.9Low83.5Confident115 Ų11560.6 Ų60.662%0.61533%0.327SS*.SBendtrans55.432.5-175.1-87.4-3.5000113.9M461 D462 A463M461-N465 VanDerWaalsContact CE-C 3.49Å; M461-N465 WeakPolarHBondContact CE-O 3.29Å; D462-N465 PolarHBondContact O-N 2.92Å; A463-N465 VanDerWaalsContact C-N 3.3Å; A463-N465 PolarHBondContact O-N 3.3Å
466K72.5Confident83.5Confident87 Ų8761 Ų6138%0.37833%0.329SS..  trans-98.8136.2173.5-69-178.6-179.1176.90111M461 D462 D464 T468M461-K466 CarbonylContact C-O 3.57Å; M461-K466 VanDerWaalsContact CA-O 3.27Å; M461-K466 WeakPolarHBondContact CA-O 3.3Å; D462-K466 PolarHBondContact N-O 3.41Å; D464-K466 HydrophobicContact CB-CG 4.46Å; D464-K466 PolarHBondContact O-N 2.82Å; K466-T468 PolarHBondContact O-N 3.35Å
467P75.4Confident83.2Confident33 Ų3369 Ų6921%0.21436%0.361CS..EExtended strand (participates in β ladder)trans-63.9125.7174.627.1-31.9000109.4V460 M461 F470 P485V460-P467 CarbonylContact O-C 3.26Å; V460-P467 WeakPolarHBondContact O-CA 3.36Å; M461-P467 HydrophobicContact SD-CB 3.96Å; P467-F470 HydrophobicContact CB-CE2 4.49Å; P467-F470 HydrophobicContact CB-CZ 4.09Å; P467-P485 HydrophobicContact CB-CG 4.45Å; P467-P485 WeakPolarHBondContact O-CG 2.94Å
468T82.8Confident82.7Confident62 Ų6269 Ų6938%0.3836%0.361SS..EExtended strand (participates in β ladder)trans-105.1-31.3177.851.50000111.9V460 D462 K466 P485V460-T468 PolarHBondContact O-N 2.94Å; V460-T468 PolarHBondContact O-OG1 2.85Å; D462-T468 HydrophobicContact CB-CG2 3.62Å; K466-T468 PolarHBondContact O-N 3.35Å; T468-P485 WeakPolarHBondContact O-CD 3.43Å
469N89.6Confident81.9Confident47 Ų4769.4 Ų69.425%0.25138%0.383SS..EExtended strand (participates in β ladder)trans-155144.6-179-156.5-7.1000111.3V460 A483V460-N469 HydrophobicContact CB-CB 4.27Å; V460-N469 HydrophobicContact CG2-CB 4.43Å; V460-N469 PolarHBondContact N-O 2.84Å; N469-A483 PolarHBondContact OD1-N 2.02Å; N469-A483 PolarHBondContact OD1-O 3.21Å
470F89.9Confident81.5Confident7 Ų768.8 Ų68.83%0.03139%0.389CS..EExtended strand (participates in β ladder)trans-105.1136.1169.4-63.2-83.7000108.7L132 I440 P451 C456 N458 K459 P467 S482 A483 P485L132-F470 HydrophobicContact CD2-CD1 3.74Å; L132-F470 HydrophobicContact CD2-CE1 4.09Å; I440-F470 HydrophobicContact CG2-CD2 3.79Å; I440-F470 HydrophobicContact CG2-CE2 3.64Å; I440-F470 HydrophobicContact CG2-CZ 4.48Å; P451-F470 HydrophobicContact CB-CD1 3.79Å; P451-F470 HydrophobicContact CB-CE1 3.8Å; P451-F470 HydrophobicContact CB-CG 4.28Å; P451-F470 HydrophobicContact CB-CZ 4.32Å; P451-F470 HydrophobicContact CG-CD1 3.95Å; P451-F470 HydrophobicContact CG-CD2 4.4Å; P451-F470 HydrophobicContact CG-CE1 3.51Å; P451-F470 HydrophobicContact CG-CE2 4.02Å; P451-F470 HydrophobicContact CG-CG 4.36Å; P451-F470 HydrophobicContact CG-CZ 3.55Å; C456-F470 HydrophobicContact CB-CB 4.12Å; N458-F470 WeakPolarHBondContact O-CA 3.48Å; K459-F470 HydrophobicContact CB-CD1 3.81Å; K459-F470 HydrophobicContact CB-CE1 3.77Å; P467-F470 HydrophobicContact CB-CE2 4.49Å; P467-F470 HydrophobicContact CB-CZ 4.09Å; F470-S482 CarbonylContact O-C 3.3Å; F470-S482 WeakPolarHBondContact O-CA 3.43Å; F470-A483 HydrophobicContact CB-CB 4.32Å; F470-A483 PolarHBondContact N-O 3.01Å; F470-A483 PolarHBondContact O-N 3.38Å; F470-P485 HydrophobicContact CE2-CB 4.32Å; F470-P485 HydrophobicContact CE2-CG 4.06Å
471T90.3Very high81.6Confident36 Ų3666.1 Ų66.122%0.22138%0.375CS..EExtended strand (participates in β ladder)trans-131.1162.8-174.5560000111.7L457 N458 V460 C473L457-T471 PolarHBondContact N-O 3.3Å; N458-T471 WeakPolarHBondContact CB-OG1 2.95Å; N458-T471 PolarHBondContact N-O 2.92Å; N458-T471 PolarHBondContact O-N 2.84Å; V460-T471 HydrophobicContact CG2-CG2 4.28Å; T471-C473 VanDerWaalsContact C-N 3.34Å
472N90.1Very high82.1Confident92 Ų9264.1 Ų64.149%0.49237%0.367SS..  trans5844.6-175.3-63.3-35.2000112.4L457 N458 G481L457-N472 HydrophobicContact CB-CB 4.08Å; L457-N472 HydrophobicContact CD1-CB 4.21Å; L457-N472 HydrophobicContact CG-CB 4.44Å; L457-N472 PolarHBondContact N-O 3.12Å; N458-N472 PolarHBondContact ND2-ND2 3.32Å; N472-G481 PolarHBondContact N-O 3.22Å; N472-G481 VanDerWaalsContact N-O 3.12Å
473C90.7Very high82.7Confident5 Ų559.8 Ų59.83%0.03435%0.345CS..  trans-83.8110.5178.4-52.90000111.2A454 G455 C456 T471 C475 I476 G481A454-C473 CarbonylContact O-C 3.54Å; A454-C473 WeakPolarHBondContact O-CB 3.09Å; G455-C473 WeakPolarHBondContact O-CA 3.43Å; C456-C473 VanDerWaalsContact CA-SG 3.59Å; C456-C473 HydrophobicContact CB-CB 4.08Å; C456-C473 WeakPolarHBondContact CB-SG 3.44Å; C456-C473 WeakPolarHBondContact SG-CB 3.49Å; C456-C473 CovalentContact SG-SG 2.04Å; C456-C473 PolarHBondContact SG-SG 3.28Å; T471-C473 VanDerWaalsContact C-N 3.34Å; C473-C475 PolarHBondContact O-N 2.88Å; C473-I476 HydrophobicContact CB-CB 4.33Å; C473-I476 HydrophobicContact CB-CD1 3.54Å; C473-I476 HydrophobicContact CB-CG1 3.82Å; C473-I476 PolarHBondContact O-N 2.93Å; C473-G481 WeakPolarHBondContact CB-O 3.21Å; C473-G481 PolarHBondContact N-O 3.5Å
474R89.6Confident83.5Confident117 Ų11761.6 Ų61.644%0.44234%0.336SS..THydrogen-bonded Turntrans-64.5-23.1-175.1-65.2-179-176.8170.82.5114.6C426 A454 G455C426-R474 HydrophobicContact CB-CB 4.42Å; A454-R474 PolarHBondContact O-N 2.96Å; G455-R474 PolarHBondContact O-N 3.3Å; G455-R474 VanDerWaalsContact O-N 3.1Å
475C87.9Confident84.5Confident3 Ų358.2 Ų58.22%0.0232%0.321CS..THydrogen-bonded Turntrans-92.94.1-176.3-59.90000113.7C426 Y448 A454 C473C426-C475 HydrophobicContact CB-CB 4.14Å; C426-C475 WeakPolarHBondContact CB-SG 3.32Å; C426-C475 WeakPolarHBondContact SG-CA 3.42Å; C426-C475 WeakPolarHBondContact SG-CB 3.44Å; C426-C475 CovalentContact SG-SG 2.03Å; C426-C475 PolarHBondContact SG-SG 2.65Å; Y448-C475 HydrophobicContact CE1-CB 3.87Å; Y448-C475 PolarHBondContact OH-O 2.8Å; A454-C475 VanDerWaalsContact O-CB 3.26Å; A454-C475 WeakPolarHBondContact O-CB 3.07Å; A454-C475 PolarHBondContact O-N 2.83Å; C473-C475 PolarHBondContact O-N 2.88Å
476I90Very high85.4Confident9 Ų953.7 Ų53.75%0.04630%0.302CS..  trans-110.7106.5-178.5-54.2-178000108.5S443 N444 Y448 C473 D478 S482 A483S443-I476 WeakPolarHBondContact OG-CG2 3.18Å; N444-I476 HydrophobicContact CB-CG2 4.26Å; Y448-I476 HydrophobicContact CE2-CD1 4.29Å; Y448-I476 HydrophobicContact CE2-CG1 3.95Å; C473-I476 HydrophobicContact CB-CB 4.33Å; C473-I476 HydrophobicContact CB-CD1 3.54Å; C473-I476 HydrophobicContact CB-CG1 3.82Å; C473-I476 PolarHBondContact O-N 2.93Å; I476-D478 PolarHBondContact O-N 3.18Å; I476-S482 WeakPolarHBondContact CD1-O 3.39Å; I476-A483 HydrophobicContact CD1-CB 3.79Å
477Y82.2Confident86.1Confident169 Ų16951.3 Ų51.366%0.66330%0.295SS*.  trans-100.650.7-169.8-55.5-78.3000113.4C426C426-Y477 WeakPolarHBondContact CB-OH 3.19Å
478D79Confident86.7Confident65 Ų6552.1 Ų52.135%0.34830%0.3SS..SBendtrans-118.85.9-177.678.1-28.7000113.9S443 N444 I476 S480 G481S443-D478 WeakPolarHBondContact CB-OD2 3.1Å; S443-D478 PolarHBondContact OG-OD1 3.04Å; S443-D478 PolarHBondContact OG-OD2 2.89Å; N444-D478 HydrophobicContact CB-CB 4.39Å; I476-D478 PolarHBondContact O-N 3.18Å; D478-S480 VanDerWaalsContact C-N 3.26Å; D478-S480 PolarHBondContact O-N 3.45Å; D478-S480 PolarHBondContact OD1-N 2.96Å; D478-S480 PolarHBondContact OD1-OG 2.91Å; D478-S480 VanDerWaalsContact OD1-OG 3.12Å; D478-S480 PolarHBondContact OD2-OG 3.05Å; D478-G481 PolarHBondContact OD1-N 3.36Å
479G67.8Low86.6Confident86 Ų8650.2 Ų50.289%0.88729%0.294SS*.SBendtrans83.7-19.1-178.800000115.1
480S78.2Confident86Confident65 Ų6549.7 Ų49.746%0.45529%0.294SS..SBendtrans-91.8-31.5174.379.50000112.3S443 D478 S482S443-S480 WeakPolarHBondContact CB-OG 3.22Å; S443-S480 PolarHBondContact OG-OG 3.11Å; D478-S480 VanDerWaalsContact C-N 3.26Å; D478-S480 PolarHBondContact O-N 3.45Å; D478-S480 PolarHBondContact OD1-N 2.96Å; D478-S480 PolarHBondContact OD1-OG 2.91Å; D478-S480 VanDerWaalsContact OD1-OG 3.12Å; D478-S480 PolarHBondContact OD2-OG 3.05Å; S480-S482 PolarHBondContact O-N 2.9Å; S480-S482 PolarHBondContact OG-OG 3.41Å; S480-S482 VanDerWaalsContact OG-OG 3.12Å
481G86.6Confident85.4Confident11 Ų1155.1 Ų55.111%0.11333%0.332CS..  trans5734.2177.400000112.6N472 C473 D478N472-G481 PolarHBondContact N-O 3.22Å; N472-G481 VanDerWaalsContact N-O 3.12Å; C473-G481 WeakPolarHBondContact CB-O 3.21Å; C473-G481 PolarHBondContact N-O 3.5Å; D478-G481 PolarHBondContact OD1-N 3.36Å
482S91.6Very high85.2Confident26 Ų2654 Ų5418%0.18233%0.326CS..  trans-117.8154.1-172.768.20000112.2S443 F470 I476 S480S443-S482 WeakPolarHBondContact CB-O 3.34Å; S443-S482 PolarHBondContact N-O 3Å; S443-S482 PolarHBondContact OG-O 3.1Å; F470-S482 CarbonylContact O-C 3.3Å; F470-S482 WeakPolarHBondContact O-CA 3.43Å; I476-S482 WeakPolarHBondContact CD1-O 3.39Å; S480-S482 PolarHBondContact O-N 2.9Å; S480-S482 PolarHBondContact OG-OG 3.41Å; S480-S482 VanDerWaalsContact OG-OG 3.12Å
483A92.1Very high84.9Confident1 Ų153.3 Ų53.31%0.00833%0.328CS..EExtended strand (participates in β ladder)trans-147.2137.2179.300000112.5I440 C441 N469 F470 I476I440-A483 HydrophobicContact CB-CB 4.3Å; I440-A483 HydrophobicContact CD1-CB 3.67Å; I440-A483 HydrophobicContact CG1-CB 4.31Å; C441-A483 CarbonylContact O-C 3.43Å; C441-A483 WeakPolarHBondContact O-CA 3.29Å; C441-A483 WeakPolarHBondContact O-CB 3.28Å; N469-A483 PolarHBondContact OD1-N 2.02Å; N469-A483 PolarHBondContact OD1-O 3.21Å; F470-A483 HydrophobicContact CB-CB 4.32Å; F470-A483 PolarHBondContact N-O 3.01Å; F470-A483 PolarHBondContact O-N 3.38Å; I476-A483 HydrophobicContact CD1-CB 3.79Å
484Q91.8Very high84.8Confident133 Ų13359.3 Ų59.362%0.62136%0.355SS*.EExtended strand (participates in β ladder)trans-87.8145.1176.6-66.1-177.42.300111.1I440 C441I440-Q484 CarbonylContact C-O 3.59Å; I440-Q484 WeakPolarHBondContact CA-O 3.46Å; I440-Q484 WeakPolarHBondContact CB-O 3.48Å; C441-Q484 PolarHBondContact N-O 3.02Å; C441-Q484 PolarHBondContact O-N 3.37Å
485P87.8Confident85Confident53 Ų5355.9 Ų55.934%0.34435%0.346SS..EExtended strand (participates in β ladder)trans-59.1143.5171.2-14.823.2000112.5P467 T468 F470P467-P485 HydrophobicContact CB-CG 4.45Å; P467-P485 WeakPolarHBondContact O-CG 2.94Å; T468-P485 WeakPolarHBondContact O-CD 3.43Å; F470-P485 HydrophobicContact CE2-CB 4.32Å; F470-P485 HydrophobicContact CE2-CG 4.06Å
486G87.6Confident85.3Confident20 Ų2056.6 Ų56.621%0.20635%0.349CS..SBendtrans91.3-176.2178.200000113.6P439 I440 C441P439-G486 CarbonylContact C-O 3.48Å; P439-G486 CarbonylContact O-C 3.42Å; P439-G486 VanDerWaalsContact O-CA 3.26Å; P439-G486 WeakPolarHBondContact O-CA 3.32Å; P439-G486 PolarHBondContact O-N 3.26Å; I440-G486 CarbonylContact C-O 3.54Å; I440-G486 WeakPolarHBondContact CA-O 3.34Å; I440-G486 PolarHBondContact N-O 3.26Å; C441-G486 PolarHBondContact N-O 3.48Å
487T87.9Confident85.4Confident37 Ų3762 Ų6223%0.22738%0.378CS..  trans-76.1159.8-178.466.30000111.2L236 P439 E447 G489L236-T487 HydrophobicContact CD1-CG2 3.61Å; L236-T487 HydrophobicContact CG-CG2 3.82Å; P439-T487 HydrophobicContact CB-CG2 4.35Å; P439-T487 HydrophobicContact CG-CG2 4.42Å; E447-T487 WeakPolarHBondContact OE1-CG2 3.27Å; E447-T487 WeakPolarHBondContact OE2-CA 3.37Å; E447-T487 VanDerWaalsContact OE2-CB 3.26Å; E447-T487 WeakPolarHBondContact OE2-CB 3.16Å; T487-G489 PolarHBondContact O-N 3.4Å; T487-G489 PolarHBondContact OG1-N 3.49Å
488C87.4Confident86.1Confident50 Ų5056.4 Ų56.434%0.33836%0.362SS..  trans-66.5-0.6173.2-71.60000113.8C441 E447C441-C488 WeakPolarHBondContact CA-SG 3.44Å; C441-C488 HydrophobicContact CB-CB 3.9Å; C441-C488 WeakPolarHBondContact CB-SG 3.49Å; C441-C488 WeakPolarHBondContact SG-CA 3.21Å; C441-C488 WeakPolarHBondContact SG-CB 3.17Å; C441-C488 CovalentContact SG-SG 2.04Å; C441-C488 PolarHBondContact SG-SG 3.12Å; E447-C488 PolarHBondContact OE2-N 3.22Å
489G79.8Confident86.8Confident23 Ų2353.3 Ų53.324%0.23735%0.345CS..  trans66.6-169.8-173.300000111.9T487T487-G489 PolarHBondContact O-N 3.4Å; T487-G489 PolarHBondContact OG1-N 3.49Å
490S77.9Confident88.1Confident36 Ų3650 Ų5025%0.25231%0.307SS..  trans-142.5119.8-17668.80000110S346 C492S346-S490 WeakPolarHBondContact OG-CB 3.45Å; S346-S490 PolarHBondContact OG-OG 2.81Å; S346-S490 VanDerWaalsContact OG-OG 3.08Å; S490-C492 WeakPolarHBondContact CB-SG 3.26Å; S490-C492 PolarHBondContact O-N 2.97Å; S490-C492 PolarHBondContact OG-SG 3.42Å
491S77.6Confident89Confident120 Ų12051.4 Ų51.484%0.83931%0.309SS*.THydrogen-bonded Turntrans-70.213.1-175.6-48.20000115.2H494S491-H494 PolarHBondContact O-ND1 2.87Å
492C86.6Confident89.4Confident14 Ų1452.7 Ų52.710%0.09531%0.313CS..THydrogen-bonded Turntrans-111.315.3-17039.10000112.5C408 S490 H494 L495C408-C492 VanDerWaalsContact CA-SG 3.52Å; C408-C492 HydrophobicContact CB-CB 4.01Å; C408-C492 WeakPolarHBondContact CB-SG 3.29Å; C408-C492 WeakPolarHBondContact SG-CB 3.27Å; C408-C492 CovalentContact SG-SG 1.99Å; C408-C492 PolarHBondContact SG-SG 3.28Å; S490-C492 WeakPolarHBondContact CB-SG 3.26Å; S490-C492 PolarHBondContact O-N 2.97Å; S490-C492 PolarHBondContact OG-SG 3.42Å; C492-H494 PolarHBondContact O-N 3.36Å; C492-L495 HydrophobicContact CB-CD1 3.98Å; C492-L495 HydrophobicContact CB-CG 4.46Å; C492-L495 WeakPolarHBondContact O-CB 3.29Å; C492-L495 PolarHBondContact O-N 2.99Å
493S83.4Confident89.6Confident77 Ų7752.5 Ų52.554%0.53831%0.309SS..G310 helixtrans-54.7-33.9176.655.80000112.8L495 L496S493-L495 PolarHBondContact O-N 2.92Å; S493-L496 VanDerWaalsContact O-CB 3.28Å; S493-L496 WeakPolarHBondContact O-CB 3.38Å; S493-L496 PolarHBondContact O-N 3.34Å; S493-L496 VanDerWaalsContact O-N 3.13Å
494H89.1Confident89.7Confident130 Ų13052.7 Ų52.760%0.60231%0.311SS*.G310 helixtrans-61.9-22.3175.869.9-85.9000113.9S491 C492 L496 P498S491-H494 PolarHBondContact O-ND1 2.87Å; C492-H494 PolarHBondContact O-N 3.36Å; H494-L496 VanDerWaalsContact C-N 3.35Å; H494-P498 WeakPolarHBondContact O-CD 3.37Å
495L93.3Very high90Very high46 Ų4650 Ų5024%0.24130%0.3CS..G310 helixtrans-81.8-12.9178.2-62.2178.4000113.3F345 I406 C492 S493 P498 F499F345-L495 HydrophobicContact CE1-CB 4.01Å; I406-L495 HydrophobicContact CG2-CB 3.94Å; I406-L495 WeakPolarHBondContact CG2-O 3.45Å; C492-L495 HydrophobicContact CB-CD1 3.98Å; C492-L495 HydrophobicContact CB-CG 4.46Å; C492-L495 WeakPolarHBondContact O-CB 3.29Å; C492-L495 PolarHBondContact O-N 2.99Å; S493-L495 PolarHBondContact O-N 2.92Å; L495-P498 WeakPolarHBondContact O-CD 3.43Å; L495-P498 WeakPolarHBondContact O-CG 3.26Å; L495-F499 WeakPolarHBondContact O-CB 3.46Å; L495-F499 PolarHBondContact O-N 3.46Å
496L93.4Very high90.3Very high18 Ų1847.6 Ų47.69%0.09428%0.284CS..Hα-helixtrans-66.6-46.1-179.517861.8000111.7I341 F345 Q347 M355 S493 H494 F499 I500I341-L496 HydrophobicContact CG2-CD1 4.07Å; F345-L496 HydrophobicContact CB-CD1 3.97Å; F345-L496 HydrophobicContact CD1-CB 3.95Å; F345-L496 HydrophobicContact CD1-CD1 4.18Å; F345-L496 HydrophobicContact CD2-CD1 3.78Å; F345-L496 HydrophobicContact CE1-CB 4.4Å; F345-L496 HydrophobicContact CE2-CD1 4.31Å; F345-L496 HydrophobicContact CG-CB 4.29Å; F345-L496 HydrophobicContact CG-CD1 3.72Å; Q347-L496 HydrophobicContact CG-CD2 3.77Å; M355-L496 HydrophobicContact CE-CD1 4.39Å; M355-L496 HydrophobicContact CE-CD2 3.77Å; M355-L496 HydrophobicContact CE-CG 4.25Å; M355-L496 HydrophobicContact SD-CD1 4.25Å; S493-L496 VanDerWaalsContact O-CB 3.28Å; S493-L496 WeakPolarHBondContact O-CB 3.38Å; S493-L496 PolarHBondContact O-N 3.34Å; S493-L496 VanDerWaalsContact O-N 3.13Å; H494-L496 VanDerWaalsContact C-N 3.35Å; L496-F499 WeakPolarHBondContact O-CB 3.3Å; L496-F499 PolarHBondContact O-N 3.01Å; L496-I500 HydrophobicContact CD1-CD1 4.38Å; L496-I500 HydrophobicContact CD1-CG1 4.03Å; L496-I500 HydrophobicContact CG-CG1 4.4Å; L496-I500 WeakPolarHBondContact O-CG1 3.21Å; L496-I500 PolarHBondContact O-N 3.19Å
497L93.4Very high90.6Very high122 Ų12248 Ų4864%0.63928%0.284SS*.Hα-helixtrans-59.4-52.4-179.4-174.667.9000113F499 I500 I501L497-F499 VanDerWaalsContact C-N 3.26Å; L497-F499 PolarHBondContact O-N 3.05Å; L497-I500 PolarHBondContact O-N 2.99Å; L497-I501 HydrophobicContact CD1-CD1 4.49Å; L497-I501 HydrophobicContact CG-CD1 4.15Å; L497-I501 WeakPolarHBondContact O-CG1 3.24Å; L497-I501 PolarHBondContact O-N 3.21Å
498P94.9Very high91Very high51 Ų5148.9 Ų48.933%0.33129%0.285SS..Hα-helixtrans-62.4-33.7176.823.2-32.5000112.3H494 L495 I501 L502H494-P498 WeakPolarHBondContact O-CD 3.37Å; L495-P498 WeakPolarHBondContact O-CD 3.43Å; L495-P498 WeakPolarHBondContact O-CG 3.26Å; P498-I501 PolarHBondContact O-N 3.05Å; P498-L502 WeakPolarHBondContact O-CG 3.26Å; P498-L502 PolarHBondContact O-N 2.94Å
499F95.7Very high91.4Very high0 Ų047 Ų470%027%0.271CS..Hα-helixtrans-61.7-47.3173.9-178.4-90.9000112.2M337 F340 I341 F345 M403 I406 L495 L496 L497 I501 L502 M503 L587M337-F499 HydrophobicContact SD-CZ 4.41Å; F340-F499 HydrophobicContact CD1-CE1 4.4Å; F340-F499 AromaticContact CD1-CZ 3.96Å; F340-F499 HydrophobicContact CD1-CZ 3.96Å; F340-F499 HydrophobicContact CE1-CE1 4.18Å; F340-F499 AromaticContact CE1-CE2 3.86Å; F340-F499 HydrophobicContact CE1-CE2 3.86Å; F340-F499 AromaticContact CE1-CZ 3.44Å; F340-F499 HydrophobicContact CE1-CZ 3.44Å; F340-F499 VanDerWaalsContact CE1-CZ 3.44Å; F340-F499 HydrophobicContact CZ-CZ 4.48Å; I341-F499 HydrophobicContact CG1-CE1 4.32Å; F345-F499 HydrophobicContact CE1-CB 4.4Å; F345-F499 HydrophobicContact CE2-CB 4.2Å; F345-F499 AromaticContact CE2-CD1 3.72Å; F345-F499 HydrophobicContact CE2-CD1 3.72Å; F345-F499 HydrophobicContact CE2-CD2 4.11Å; F345-F499 HydrophobicContact CE2-CE1 4.11Å; F345-F499 HydrophobicContact CE2-CE2 4.46Å; F345-F499 AromaticContact CE2-CG 3.73Å; F345-F499 HydrophobicContact CE2-CG 3.73Å; F345-F499 HydrophobicContact CE2-CZ 4.48Å; F345-F499 HydrophobicContact CZ-CB 3.65Å; F345-F499 HydrophobicContact CZ-CD1 4.04Å; F345-F499 AromaticContact CZ-CD2 3.86Å; F345-F499 HydrophobicContact CZ-CD2 3.86Å; F345-F499 AromaticContact CZ-CG 3.57Å; F345-F499 HydrophobicContact CZ-CG 3.57Å; M403-F499 HydrophobicContact CB-CD2 4.32Å; M403-F499 HydrophobicContact CB-CE2 4.02Å; M403-F499 HydrophobicContact CG-CD2 4.45Å; M403-F499 HydrophobicContact CG-CE2 4.37Å; M403-F499 HydrophobicContact SD-CE2 4.19Å; M403-F499 HydrophobicContact SD-CZ 4.5Å; I406-F499 HydrophobicContact CG2-CB 3.97Å; I406-F499 HydrophobicContact CG2-CD2 4.4Å; L495-F499 WeakPolarHBondContact O-CB 3.46Å; L495-F499 PolarHBondContact O-N 3.46Å; L496-F499 WeakPolarHBondContact O-CB 3.3Å; L496-F499 PolarHBondContact O-N 3.01Å; L497-F499 VanDerWaalsContact C-N 3.26Å; L497-F499 PolarHBondContact O-N 3.05Å; F499-I501 VanDerWaalsContact C-N 3.35Å; F499-I501 PolarHBondContact O-N 2.78Å; F499-L502 PolarHBondContact O-N 2.89Å; F499-M503 HydrophobicContact CE1-SD 4.3Å; F499-M503 VanDerWaalsContact O-CB 3.31Å; F499-M503 WeakPolarHBondContact O-CB 3.45Å; F499-M503 PolarHBondContact O-N 3.47Å; F499-L587 HydrophobicContact CE2-CD1 4Å
500I95Very high92.1Very high17 Ų1746.4 Ų46.49%0.08726%0.263CS..Hα-helixtrans-65.4-37.9179.4-65.8-60.6000111.7I341 M355 I359 L496 L497 M503 G504I341-I500 HydrophobicContact CD1-CD1 3.93Å; M355-I500 HydrophobicContact CB-CD1 4.12Å; M355-I500 HydrophobicContact CG-CD1 4.24Å; M355-I500 HydrophobicContact SD-CD1 3.67Å; M355-I500 HydrophobicContact SD-CG1 3.97Å; I359-I500 HydrophobicContact CD1-CG2 4.18Å; L496-I500 HydrophobicContact CD1-CD1 4.38Å; L496-I500 HydrophobicContact CD1-CG1 4.03Å; L496-I500 HydrophobicContact CG-CG1 4.4Å; L496-I500 WeakPolarHBondContact O-CG1 3.21Å; L496-I500 PolarHBondContact O-N 3.19Å; L497-I500 PolarHBondContact O-N 2.99Å; I500-M503 PolarHBondContact O-N 3.32Å; I500-G504 PolarHBondContact O-N 3.1Å
501I95.5Very high92.8Very high95 Ų9545.4 Ų45.449%0.48726%0.255SS..Hα-helixtrans-61.8-50175.2-68.2168.3000110.4L497 P498 F499 M503 G504 I505L497-I501 HydrophobicContact CD1-CD1 4.49Å; L497-I501 HydrophobicContact CG-CD1 4.15Å; L497-I501 WeakPolarHBondContact O-CG1 3.24Å; L497-I501 PolarHBondContact O-N 3.21Å; P498-I501 PolarHBondContact O-N 3.05Å; F499-I501 VanDerWaalsContact C-N 3.35Å; F499-I501 PolarHBondContact O-N 2.78Å; I501-M503 PolarHBondContact O-N 2.95Å; I501-G504 PolarHBondContact O-N 3.23Å; I501-I505 HydrophobicContact CG2-CD1 3.91Å; I501-I505 WeakPolarHBondContact O-CG1 3.27Å; I501-I505 PolarHBondContact O-N 3.47Å
502L95.9Very high93.6Very high37 Ų3741 Ų4119%0.19422%0.221CC..Hα-helixtrans-61.6-45177.8-75169.4000111.6P402 M403 I406 P498 F499 G504 I505 T506P402-L502 HydrophobicContact CB-CD1 4.11Å; M403-L502 HydrophobicContact CG-CB 3.82Å; M403-L502 HydrophobicContact CG-CD1 4.17Å; M403-L502 HydrophobicContact SD-CB 4.08Å; I406-L502 HydrophobicContact CD1-CD1 3.45Å; I406-L502 VanDerWaalsContact CD1-CD1 3.45Å; P498-L502 WeakPolarHBondContact O-CG 3.26Å; P498-L502 PolarHBondContact O-N 2.94Å; F499-L502 PolarHBondContact O-N 2.89Å; L502-G504 VanDerWaalsContact C-N 3.3Å; L502-G504 PolarHBondContact O-N 2.62Å; L502-I505 PolarHBondContact O-N 2.89Å; L502-T506 WeakPolarHBondContact O-CB 3.48Å; L502-T506 PolarHBondContact O-N 3.23Å; L502-T506 PolarHBondContact O-OG1 3.07Å
503M95.3Very high93.9Very high23 Ų2340.5 Ų40.511%0.11322%0.218CC..Hα-helixtrans-59.4-41.4176.6-169-164.811400111.7M337 I341 I356 M403 F499 I500 I501 T506 S507M337-M503 HydrophobicContact CE-CG 4.22Å; M337-M503 HydrophobicContact CE-SD 3.98Å; M337-M503 HydrophobicContact CG-CE 4.41Å; M337-M503 HydrophobicContact CG-SD 3.82Å; M337-M503 HydrophobicContact SD-SD 4.18Å; I341-M503 HydrophobicContact CD1-SD 4.41Å; I356-M503 HydrophobicContact CD1-CE 3.45Å; I356-M503 VanDerWaalsContact CD1-CE 3.45Å; I356-M503 HydrophobicContact CD1-SD 4.18Å; M403-M503 HydrophobicContact SD-CB 4.14Å; F499-M503 HydrophobicContact CE1-SD 4.3Å; F499-M503 VanDerWaalsContact O-CB 3.31Å; F499-M503 WeakPolarHBondContact O-CB 3.45Å; F499-M503 PolarHBondContact O-N 3.47Å; I500-M503 PolarHBondContact O-N 3.32Å; I501-M503 PolarHBondContact O-N 2.95Å; M503-T506 PolarHBondContact O-N 3.43Å; M503-S507 VanDerWaalsContact O-CB 3.3Å; M503-S507 WeakPolarHBondContact O-CB 3.41Å; M503-S507 PolarHBondContact O-N 2.81Å
504G95.4Very high94.3Very high4 Ų442 Ų424%0.04122%0.216CC..Hα-helixtrans-63.2-46.5175.600000112.5I500 I501 L502 S507 F508I500-G504 PolarHBondContact O-N 3.1Å; I501-G504 PolarHBondContact O-N 3.23Å; L502-G504 VanDerWaalsContact C-N 3.3Å; L502-G504 PolarHBondContact O-N 2.62Å; G504-S507 PolarHBondContact O-N 3.18Å; G504-F508 WeakPolarHBondContact O-CB 3.41Å; G504-F508 PolarHBondContact O-N 3.17Å
505I96.1Very high94.2Very high78 Ų7837.5 Ų37.540%0.420%0.198SC..Hα-helixtrans-59.8-46.9174.8-68.9167.1000110.4I501 L502 F508 I509I501-I505 HydrophobicContact CG2-CD1 3.91Å; I501-I505 WeakPolarHBondContact O-CG1 3.27Å; I501-I505 PolarHBondContact O-N 3.47Å; L502-I505 PolarHBondContact O-N 2.89Å; I505-F508 WeakPolarHBondContact O-CB 3.4Å; I505-F508 PolarHBondContact O-N 2.82Å; I505-I509 HydrophobicContact CG2-CD1 3.64Å; I505-I509 HydrophobicContact CG2-CG1 4.41Å; I505-I509 VanDerWaalsContact O-CG1 3.27Å; I505-I509 WeakPolarHBondContact O-CG1 3.47Å; I505-I509 PolarHBondContact O-N 3.05Å
506T95.2Very high94.2Very high2 Ų235.3 Ų35.31%0.01219%0.186CC..Hα-helixtrans-62.9-44.7178.4-57.80000111.6S399 A400 M403 L502 M503 F508 I509 I510 M590S399-T506 WeakPolarHBondContact CB-OG1 3.35Å; S399-T506 PolarHBondContact OG-OG1 2.76Å; A400-T506 HydrophobicContact CB-CG2 4.39Å; M403-T506 HydrophobicContact CE-CG2 4.32Å; L502-T506 WeakPolarHBondContact O-CB 3.48Å; L502-T506 PolarHBondContact O-N 3.23Å; L502-T506 PolarHBondContact O-OG1 3.07Å; M503-T506 PolarHBondContact O-N 3.43Å; T506-F508 VanDerWaalsContact C-N 3.31Å; T506-F508 PolarHBondContact O-N 3.26Å; T506-I509 PolarHBondContact O-N 3.08Å; T506-I510 HydrophobicContact CG2-CD1 3.63Å; T506-I510 HydrophobicContact CG2-CG1 4.23Å; T506-I510 WeakPolarHBondContact O-CB 3.41Å; T506-I510 WeakPolarHBondContact O-CD1 3.31Å; T506-I510 WeakPolarHBondContact O-CG1 3.37Å; T506-I510 PolarHBondContact O-N 3.42Å; T506-M590 HydrophobicContact CG2-CE 3.24Å
507S94.1Very high94.1Very high28 Ų2834.5 Ų34.520%0.19618%0.182CC..Hα-helixtrans-57.9-43.7175.5-176.30000111.9G360 M503 G504 S511G360-S507 PolarHBondContact O-OG 2.76Å; M503-S507 VanDerWaalsContact O-CB 3.3Å; M503-S507 WeakPolarHBondContact O-CB 3.41Å; M503-S507 PolarHBondContact O-N 2.81Å; G504-S507 PolarHBondContact O-N 3.18Å; S507-S511 VanDerWaalsContact O-CB 3.31Å; S507-S511 WeakPolarHBondContact O-CB 3.41Å; S507-S511 PolarHBondContact O-N 3Å; S507-S511 PolarHBondContact O-OG 3.35Å
508F95.8Very high93.9Very high55 Ų5532.4 Ų32.424%0.24117%0.166CC..Hα-helixtrans-60.4-50.9175.6173.2-93.7000111.8L363 L366 G367 L370 G504 I505 T506 S511 F512L363-F508 WeakPolarHBondContact O-CD2 3.21Å; L366-F508 HydrophobicContact CB-CD2 4.49Å; L366-F508 HydrophobicContact CB-CE2 4.43Å; L366-F508 HydrophobicContact CD2-CE2 4.31Å; L366-F508 HydrophobicContact CG-CD2 4.47Å; L366-F508 HydrophobicContact CG-CE2 4.03Å; G367-F508 VanDerWaalsContact CA-CE2 3.46Å; L370-F508 HydrophobicContact CD1-CE2 3.8Å; L370-F508 HydrophobicContact CD1-CZ 3.73Å; G504-F508 WeakPolarHBondContact O-CB 3.41Å; G504-F508 PolarHBondContact O-N 3.17Å; I505-F508 WeakPolarHBondContact O-CB 3.4Å; I505-F508 PolarHBondContact O-N 2.82Å; T506-F508 VanDerWaalsContact C-N 3.31Å; T506-F508 PolarHBondContact O-N 3.26Å; F508-S511 PolarHBondContact O-N 3.16Å; F508-F512 VanDerWaalsContact O-CB 3.29Å; F508-F512 WeakPolarHBondContact O-CB 3.03Å; F508-F512 PolarHBondContact O-N 3.45Å
509I95.9Very high93.5Very high10 Ų1032.9 Ų32.95%0.05117%0.165CC..Hα-helixtrans-64-44.8-178-64.8162.2000111.2A392 L395 C396 I505 T506 S511 F512 T513A392-I509 HydrophobicContact CB-CG2 4.2Å; A392-I509 WeakPolarHBondContact O-CG2 3.49Å; L395-I509 HydrophobicContact CB-CD1 4.45Å; L395-I509 HydrophobicContact CD2-CD1 3.86Å; L395-I509 HydrophobicContact CD2-CG1 4.3Å; L395-I509 HydrophobicContact CG-CD1 3.77Å; C396-I509 HydrophobicContact CB-CG2 3.83Å; I505-I509 HydrophobicContact CG2-CD1 3.64Å; I505-I509 HydrophobicContact CG2-CG1 4.41Å; I505-I509 VanDerWaalsContact O-CG1 3.27Å; I505-I509 WeakPolarHBondContact O-CG1 3.47Å; I505-I509 PolarHBondContact O-N 3.05Å; T506-I509 PolarHBondContact O-N 3.08Å; I509-S511 VanDerWaalsContact C-N 3.32Å; I509-S511 PolarHBondContact O-N 3.4Å; I509-F512 WeakPolarHBondContact O-CB 3.15Å; I509-F512 PolarHBondContact O-N 3.28Å; I509-T513 PolarHBondContact O-N 3.1Å
510I93.9Very high93.2Very high12 Ų1233 Ų336%0.06217%0.166CC..Hα-helixtrans-55.3-52.3175.9-71.6167.3000109.3M326 L329 V330 C396 T506 F512 T513 M590M326-I510 HydrophobicContact CE-CB 3.79Å; M326-I510 HydrophobicContact CE-CG1 3.84Å; M326-I510 HydrophobicContact CE-CG2 3.4Å; M326-I510 VanDerWaalsContact CE-CG2 3.4Å; L329-I510 HydrophobicContact CD2-CD1 3.6Å; L329-I510 HydrophobicContact CD2-CG1 4.36Å; V330-I510 HydrophobicContact CG2-CG2 3.93Å; C396-I510 VanDerWaalsContact SG-CG1 3.58Å; T506-I510 HydrophobicContact CG2-CD1 3.63Å; T506-I510 HydrophobicContact CG2-CG1 4.23Å; T506-I510 WeakPolarHBondContact O-CB 3.41Å; T506-I510 WeakPolarHBondContact O-CD1 3.31Å; T506-I510 WeakPolarHBondContact O-CG1 3.37Å; T506-I510 PolarHBondContact O-N 3.42Å; I510-F512 VanDerWaalsContact C-N 3.32Å; I510-F512 PolarHBondContact O-N 3.25Å; I510-T513 PolarHBondContact O-N 3.46Å; I510-T513 VanDerWaalsContact O-N 3.15Å; I510-T513 PolarHBondContact O-OG1 3.1Å; I510-M590 HydrophobicContact CD1-CE 4.39Å
511S92.7Very high92.9Very high14 Ų1432.2 Ų32.210%0.09816%0.162CC..Hα-helixtrans-68.2-31.5-176.6-53.90000112.7A364 S507 F508 I509 T513 Q514A364-S511 WeakPolarHBondContact CA-OG 3.45Å; A364-S511 VanDerWaalsContact CB-OG 3.23Å; A364-S511 WeakPolarHBondContact CB-OG 3.31Å; A364-S511 WeakPolarHBondContact O-CB 3.31Å; S507-S511 VanDerWaalsContact O-CB 3.31Å; S507-S511 WeakPolarHBondContact O-CB 3.41Å; S507-S511 PolarHBondContact O-N 3Å; S507-S511 PolarHBondContact O-OG 3.35Å; F508-S511 PolarHBondContact O-N 3.16Å; I509-S511 VanDerWaalsContact C-N 3.32Å; I509-S511 PolarHBondContact O-N 3.4Å; S511-T513 PolarHBondContact O-N 3.44Å; S511-Q514 WeakPolarHBondContact O-CB 3.16Å; S511-Q514 PolarHBondContact O-N 3.02Å; S511-Q514 VanDerWaalsContact O-N 3.14Å
512F94.4Very high92.4Very high29 Ų2929.7 Ų29.713%0.12715%0.149CC..Hα-helixtrans-59.6-33.1172.8173.4-89.6000113.2G367 L370 G371 L374 L388 A392 F508 I509 I510 Q514 P516G367-F512 VanDerWaalsContact O-CA 3.3Å; G367-F512 WeakPolarHBondContact O-CA 3.44Å; L370-F512 HydrophobicContact CB-CD2 4.31Å; G371-F512 VanDerWaalsContact CA-CD2 3.47Å; G371-F512 VanDerWaalsContact CA-CE2 3.48Å; L374-F512 HydrophobicContact CB-CE2 4.49Å; L374-F512 HydrophobicContact CD2-CE2 4.19Å; L374-F512 HydrophobicContact CD2-CZ 3.57Å; L388-F512 HydrophobicContact CD1-CE1 3.9Å; L388-F512 HydrophobicContact CD1-CZ 4.09Å; L388-F512 HydrophobicContact CD2-CE1 4.03Å; L388-F512 HydrophobicContact CD2-CZ 4.08Å; L388-F512 HydrophobicContact CG-CE1 3.97Å; L388-F512 HydrophobicContact CG-CZ 4.37Å; A392-F512 HydrophobicContact CB-CD1 4.21Å; A392-F512 HydrophobicContact CB-CE1 4.42Å; F508-F512 VanDerWaalsContact O-CB 3.29Å; F508-F512 WeakPolarHBondContact O-CB 3.03Å; F508-F512 PolarHBondContact O-N 3.45Å; I509-F512 WeakPolarHBondContact O-CB 3.15Å; I509-F512 PolarHBondContact O-N 3.28Å; I510-F512 VanDerWaalsContact C-N 3.32Å; I510-F512 PolarHBondContact O-N 3.25Å; F512-Q514 VanDerWaalsContact C-N 3.31Å; F512-Q514 PolarHBondContact O-N 2.85Å; F512-P516 WeakPolarHBondContact O-CD 3.48Å
513T94.1Very high91.9Very high3 Ų333.1 Ų33.12%0.01816%0.159CC..THydrogen-bonded Turntrans-77.2-13177.767.10000114.6A392 I393 I509 I510 S511 S517A392-T513 HydrophobicContact CB-CG2 3.4Å; A392-T513 VanDerWaalsContact CB-CG2 3.4Å; I393-T513 HydrophobicContact CD1-CG2 4.09Å; I393-T513 HydrophobicContact CG1-CG2 4.32Å; I509-T513 PolarHBondContact O-N 3.1Å; I510-T513 PolarHBondContact O-N 3.46Å; I510-T513 VanDerWaalsContact O-N 3.15Å; I510-T513 PolarHBondContact O-OG1 3.1Å; S511-T513 PolarHBondContact O-N 3.44Å; T513-S517 VanDerWaalsContact O-CB 3.23Å; T513-S517 WeakPolarHBondContact O-CB 3.45Å; T513-S517 PolarHBondContact O-N 3.48Å; T513-S517 VanDerWaalsContact O-N 3.16Å; T513-S517 PolarHBondContact O-OG 3.21Å
514Q91Very high91.5Very high109 Ų10933.8 Ų33.851%0.50917%0.165SC..Hα-helixtrans-64.2-54-175.6-118.3-144.91500112.3S511 F512 S517 Y518S511-Q514 WeakPolarHBondContact O-CB 3.16Å; S511-Q514 PolarHBondContact O-N 3.02Å; S511-Q514 VanDerWaalsContact O-N 3.14Å; F512-Q514 VanDerWaalsContact C-N 3.31Å; F512-Q514 PolarHBondContact O-N 2.85Å; Q514-S517 PolarHBondContact O-N 3.27Å; Q514-Y518 PolarHBondContact O-N 2.69Å
515T88.1Confident91Very high35 Ų3534.3 Ų34.322%0.21517%0.167CC..Hα-helixtrans-62.2-48.7-177-48.40000112.8V368 S517 Y518 M519V368-T515 WeakPolarHBondContact CG1-OG1 3.24Å; V368-T515 PolarHBondContact O-OG1 2.61Å; T515-S517 VanDerWaalsContact C-N 3.3Å; T515-S517 PolarHBondContact O-N 2.88Å; T515-Y518 PolarHBondContact O-N 2.83Å; T515-M519 WeakPolarHBondContact O-CG 3.23Å; T515-M519 PolarHBondContact O-N 3.49Å
516P92Very high90.3Very high0 Ų033.7 Ų33.70%017%0.168CC..Hα-helixtrans-57.7-40.7175-23.733.4000113.1M375 L388 F512 M519 M520M375-P516 HydrophobicContact CG-CB 3.91Å; M375-P516 HydrophobicContact CG-CG 3.74Å; M375-P516 HydrophobicContact SD-CB 3.83Å; M375-P516 HydrophobicContact SD-CG 4.25Å; L388-P516 HydrophobicContact CD2-CB 4.42Å; L388-P516 HydrophobicContact CD2-CG 4.04Å; F512-P516 WeakPolarHBondContact O-CD 3.48Å; P516-M519 PolarHBondContact O-N 3.32Å; P516-M520 WeakPolarHBondContact O-CG 3.19Å; P516-M520 PolarHBondContact O-N 3.36Å
517S92.8Very high89.4Confident1 Ų138.3 Ų38.31%0.00720%0.198CC..Hα-helixtrans-68.2-41.4-179.5-58.30000112C389 T513 Q514 T515 M519 M520 V521 F601C389-S517 PolarHBondContact SG-OG 3.09Å; T513-S517 VanDerWaalsContact O-CB 3.23Å; T513-S517 WeakPolarHBondContact O-CB 3.45Å; T513-S517 PolarHBondContact O-N 3.48Å; T513-S517 VanDerWaalsContact O-N 3.16Å; T513-S517 PolarHBondContact O-OG 3.21Å; Q514-S517 PolarHBondContact O-N 3.27Å; T515-S517 VanDerWaalsContact C-N 3.3Å; T515-S517 PolarHBondContact O-N 2.88Å; S517-M519 VanDerWaalsContact C-N 3.35Å; S517-M519 PolarHBondContact O-N 3.27Å; S517-M520 WeakPolarHBondContact O-CB 3.46Å; S517-M520 PolarHBondContact O-N 3.44Å; S517-V521 PolarHBondContact O-N 3.34Å; S517-F601 VanDerWaalsContact OG-CZ 3.27Å; S517-F601 WeakPolarHBondContact OG-CZ 3.15Å
518Y88.1Confident88.4Confident77 Ų7745.1 Ų45.130%0.30223%0.227SC..Hα-helixtrans-62-41.9173.7-172.2-107.2000112Q514 T515 M520 V521 L522 V534Q514-Y518 PolarHBondContact O-N 2.69Å; T515-Y518 PolarHBondContact O-N 2.83Å; Y518-M520 VanDerWaalsContact C-N 3.29Å; Y518-M520 PolarHBondContact O-N 3.03Å; Y518-V521 WeakPolarHBondContact O-CB 3.29Å; Y518-V521 PolarHBondContact O-N 3.32Å; Y518-L522 HydrophobicContact CD1-CD1 4.05Å; Y518-L522 HydrophobicContact CE1-CD1 3.65Å; Y518-L522 HydrophobicContact CE1-CG 4.2Å; Y518-L522 PolarHBondContact O-N 2.78Å; Y518-L522 VanDerWaalsContact O-N 3.16Å; Y518-V534 HydrophobicContact CE2-CG1 4.33Å; Y518-V534 HydrophobicContact CE2-CG2 4.26Å
519M86Confident87.3Confident62 Ų6244 Ų4431%0.30522%0.223SC..Hα-helixtrans-65.3-30.2175.4-70.7-62.5-77.100113.1M375 T515 P516 S517 L522 R523M375-M519 HydrophobicContact CE-CB 3.91Å; M375-M519 HydrophobicContact CE-CG 4.42Å; T515-M519 WeakPolarHBondContact O-CG 3.23Å; T515-M519 PolarHBondContact O-N 3.49Å; P516-M519 PolarHBondContact O-N 3.32Å; S517-M519 VanDerWaalsContact C-N 3.35Å; S517-M519 PolarHBondContact O-N 3.27Å; M519-L522 HydrophobicContact SD-CD1 4.26Å; M519-R523 WeakPolarHBondContact O-CB 3.27Å; M519-R523 VanDerWaalsContact O-CG 3.28Å; M519-R523 WeakPolarHBondContact O-CG 3.32Å; M519-R523 PolarHBondContact O-N 2.9Å; M519-R523 VanDerWaalsContact O-N 3.08Å
520M90.5Very high86.3Confident2 Ų247.3 Ų47.31%0.0124%0.237CC..Hα-helixtrans-65.2-41.8172.3-71.9174.461.900111.7V319 V382 A385 P516 S517 Y518 R523 T524 T604V319-M520 HydrophobicContact CG1-CB 4.25Å; V319-M520 HydrophobicContact CG2-CE 3.68Å; V382-M520 HydrophobicContact CG1-CE 4.35Å; V382-M520 HydrophobicContact CG1-CG 4.29Å; A385-M520 HydrophobicContact CB-CG 3.66Å; A385-M520 HydrophobicContact CB-SD 3.88Å; P516-M520 WeakPolarHBondContact O-CG 3.19Å; P516-M520 PolarHBondContact O-N 3.36Å; S517-M520 WeakPolarHBondContact O-CB 3.46Å; S517-M520 PolarHBondContact O-N 3.44Å; Y518-M520 VanDerWaalsContact C-N 3.29Å; Y518-M520 PolarHBondContact O-N 3.03Å; M520-R523 PolarHBondContact O-N 2.86Å; M520-T524 WeakPolarHBondContact O-CB 3.45Å; M520-T524 WeakPolarHBondContact O-CG2 3.47Å; M520-T524 PolarHBondContact O-N 3.44Å; M520-T524 VanDerWaalsContact O-N 3.08Å; M520-T524 PolarHBondContact O-OG1 2.85Å; M520-T604 HydrophobicContact CE-CG2 3.74Å
521V88.6Confident85.2Confident1 Ų151.8 Ų51.81%0.00627%0.27CS..Hα-helixtrans-57.6-52.7175.11710000110.2Y316 V319 V320 L323 S517 Y518 R523 T524 V525Y316-V521 HydrophobicContact CD2-CG1 3.87Å; Y316-V521 HydrophobicContact CE2-CG1 3.63Å; V319-V521 HydrophobicContact CB-CG2 4.38Å; V319-V521 HydrophobicContact CG1-CG2 3.69Å; V320-V521 HydrophobicContact CG2-CG2 4.16Å; L323-V521 HydrophobicContact CD1-CG2 4.18Å; S517-V521 PolarHBondContact O-N 3.34Å; Y518-V521 WeakPolarHBondContact O-CB 3.29Å; Y518-V521 PolarHBondContact O-N 3.32Å; V521-R523 VanDerWaalsContact C-N 3.28Å; V521-R523 PolarHBondContact O-N 3.37Å; V521-T524 PolarHBondContact O-N 3.45Å; V521-T524 PolarHBondContact O-OG1 3.49Å; V521-T524 VanDerWaalsContact O-OG1 3.08Å; V521-V525 WeakPolarHBondContact O-CG2 3.28Å; V521-V525 PolarHBondContact O-N 2.95Å
522L83.9Confident84.4Confident41 Ų4153.2 Ų53.222%0.21527%0.274CS..Hα-helixtrans-61.6-33.3-178.6-66.3-179.5000113.7Y518 M519 K530 V534Y518-L522 HydrophobicContact CD1-CD1 4.05Å; Y518-L522 HydrophobicContact CE1-CD1 3.65Å; Y518-L522 HydrophobicContact CE1-CG 4.2Å; Y518-L522 PolarHBondContact O-N 2.78Å; Y518-L522 VanDerWaalsContact O-N 3.16Å; M519-L522 HydrophobicContact SD-CD1 4.26Å; L522-K530 WeakPolarHBondContact O-CE 3.49Å; L522-V534 HydrophobicContact CD2-CG2 3.63Å
523R86.7Confident83.7Confident109 Ų10951.9 Ų51.941%0.41127%0.269SS..Hα-helixtrans-87-10.8-177.8-71.5174.4175.7168.8-7.4114.2M380 V382 M519 M520 V521M380-R523 PolarHBondContact O-NH1 3.26Å; V382-R523 HydrophobicContact CG2-CB 3.53Å; V382-R523 HydrophobicContact CG2-CG 4.46Å; M519-R523 WeakPolarHBondContact O-CB 3.27Å; M519-R523 VanDerWaalsContact O-CG 3.28Å; M519-R523 WeakPolarHBondContact O-CG 3.32Å; M519-R523 PolarHBondContact O-N 2.9Å; M519-R523 VanDerWaalsContact O-N 3.08Å; M520-R523 PolarHBondContact O-N 2.86Å; V521-R523 VanDerWaalsContact C-N 3.28Å; V521-R523 PolarHBondContact O-N 3.37Å
524T86.6Confident83.1Confident38 Ų3852.8 Ų52.823%0.23327%0.274CS..Hα-helixtrans-100.1-10.2-178.853.10000113.2I315 V382 M520 V521I315-T524 HydrophobicContact CG2-CG2 3.55Å; V382-T524 HydrophobicContact CG1-CG2 3.79Å; V382-T524 HydrophobicContact CG2-CG2 4.48Å; M520-T524 WeakPolarHBondContact O-CB 3.45Å; M520-T524 WeakPolarHBondContact O-CG2 3.47Å; M520-T524 PolarHBondContact O-N 3.44Å; M520-T524 VanDerWaalsContact O-N 3.08Å; M520-T524 PolarHBondContact O-OG1 2.85Å; V521-T524 PolarHBondContact O-N 3.45Å; V521-T524 PolarHBondContact O-OG1 3.49Å; V521-T524 VanDerWaalsContact O-OG1 3.08Å
525V85.7Confident82.5Confident15 Ų1549.6 Ų49.69%0.09127%0.27CS..SBendtrans-106.1139.8178.9-178.90000109.5Y316 V521 D529 A533Y316-V525 HydrophobicContact CD2-CG2 3.67Å; Y316-V525 HydrophobicContact CE2-CG2 4.3Å; Y316-V525 HydrophobicContact CG-CG2 4.27Å; V521-V525 WeakPolarHBondContact O-CG2 3.28Å; V521-V525 PolarHBondContact O-N 2.95Å; V525-D529 HydrophobicContact CG1-CB 3.53Å; V525-A533 HydrophobicContact CB-CB 4.36Å; V525-A533 HydrophobicContact CG1-CB 3.89Å; V525-A533 HydrophobicContact CG2-CB 3.87Å
526P80.3Confident82.3Confident64 Ų6448 Ų4842%0.41626%0.26SS..  trans-53.5148.3172.6-24.734.1000111.9E528 D529 K530P526-E528 HydrophobicContact CB-CG 4.41Å; P526-E528 PolarHBondContact O-N 3.24Å; P526-E528 VanDerWaalsContact O-N 3.13Å; P526-D529 PolarHBondContact O-N 3.22Å; P526-K530 PolarHBondContact O-N 3.01Å
527P75.6Confident82.1Confident99 Ų9948.1 Ų48.164%0.64326%0.261SS*.G310 helixtrans-55.7-34.7-176.522.7-32.7000113.5D529P527-D529 VanDerWaalsContact C-N 3.31Å; P527-D529 PolarHBondContact O-N 2.89Å
528E73Confident81.7Confident171 Ų17153.1 Ų53.180%0.79928%0.281SS*.G310 helixtrans-62.9-33.7178.1-16.9176.8-14300112.7P526P526-E528 HydrophobicContact CB-CG 4.41Å; P526-E528 PolarHBondContact O-N 3.24Å; P526-E528 VanDerWaalsContact O-N 3.13Å
529D73.3Confident81.6Confident31 Ų3152.3 Ų52.317%0.16628%0.28CS..G310 helixtrans-102.5-1.4-171.7-77.7-10.6000112.7R309 V525 P526 P527 F532 A533R309-D529 IonicContact CZ-OD2 3.73Å; R309-D529 IonicContact NE-OD2 3.93Å; R309-D529 IonicContact NH2-OD1 3.08Å; R309-D529 PolarHBondContact NH2-OD1 3.45Å; R309-D529 IonicContact NH2-OD2 3.65Å; R309-D529 PolarHBondContact NH2-OD2 2.81Å; V525-D529 HydrophobicContact CG1-CB 3.53Å; P526-D529 PolarHBondContact O-N 3.22Å; P527-D529 VanDerWaalsContact C-N 3.31Å; P527-D529 PolarHBondContact O-N 2.89Å; D529-F532 PolarHBondContact O-N 2.83Å; D529-A533 WeakPolarHBondContact O-CB 3Å; D529-A533 PolarHBondContact O-N 3.4Å
530K75.8Confident81.7Confident80 Ų8050.7 Ų50.735%0.34827%0.273SS..Hα-helixtrans-58.9-52.2-173.1-78.8175.1-176.1167.20113.4L522 P526 F532 A533 V534L522-K530 WeakPolarHBondContact O-CE 3.49Å; P526-K530 PolarHBondContact O-N 3.01Å; K530-F532 VanDerWaalsContact C-N 3.27Å; K530-F532 PolarHBondContact O-N 2.79Å; K530-A533 PolarHBondContact O-N 2.78Å; K530-V534 WeakPolarHBondContact O-CG2 3.19Å; K530-V534 PolarHBondContact O-N 3.45Å
531S70.9Confident81.7Confident107 Ų10751.1 Ų51.175%0.74828%0.275SS*.Hα-helixtrans-62.4-38.8-178-55.90000111.3G535S531-G535 PolarHBondContact O-N 2.79Å
532F75.9Confident81.8Confident44 Ų4452.5 Ų52.519%0.19328%0.28CS..Hα-helixtrans-65.6-46.3175.5-177.9-94.6000111.9F303 I306 A307 T310 D529 K530 V534 G535 V536F303-F532 AromaticContact CD2-CE2 3.72Å; F303-F532 HydrophobicContact CD2-CE2 3.72Å; F303-F532 HydrophobicContact CD2-CZ 4.29Å; F303-F532 AromaticContact CE2-CE2 3.69Å; F303-F532 HydrophobicContact CE2-CE2 3.69Å; F303-F532 HydrophobicContact CE2-CZ 4.17Å; I306-F532 VanDerWaalsContact C-CE1 3.49Å; I306-F532 HydrophobicContact CB-CE1 4.04Å; I306-F532 HydrophobicContact CB-CE2 4.18Å; I306-F532 HydrophobicContact CB-CZ 3.74Å; I306-F532 HydrophobicContact CG2-CD1 3.69Å; I306-F532 HydrophobicContact CG2-CD2 4.16Å; I306-F532 HydrophobicContact CG2-CE1 3.43Å; I306-F532 VanDerWaalsContact CG2-CE1 3.43Å; I306-F532 HydrophobicContact CG2-CE2 3.92Å; I306-F532 HydrophobicContact CG2-CG 4.05Å; I306-F532 HydrophobicContact CG2-CZ 3.56Å; A307-F532 HydrophobicContact CB-CE1 4.37Å; A307-F532 HydrophobicContact CB-CZ 3.94Å; A307-F532 VanDerWaalsContact N-CZ 3.28Å; T310-F532 HydrophobicContact CG2-CD1 4.49Å; T310-F532 WeakPolarHBondContact OG1-CD1 3.38Å; T310-F532 WeakPolarHBondContact OG1-CE1 3.26Å; D529-F532 PolarHBondContact O-N 2.83Å; K530-F532 VanDerWaalsContact C-N 3.27Å; K530-F532 PolarHBondContact O-N 2.79Å; F532-V534 PolarHBondContact O-N 2.92Å; F532-G535 WeakPolarHBondContact O-CA 3.46Å; F532-G535 PolarHBondContact O-N 3.42Å; F532-G535 VanDerWaalsContact O-N 3.11Å; F532-V536 HydrophobicContact CD1-CG2 4.09Å; F532-V536 HydrophobicContact CE1-CG2 3.55Å; F532-V536 HydrophobicContact CE2-CG2 4.48Å; F532-V536 HydrophobicContact CZ-CG2 3.77Å; F532-V536 WeakPolarHBondContact O-CG2 3.28Å; F532-V536 PolarHBondContact O-N 3.18Å
533A80.1Confident82.2Confident1 Ų154 Ų541%0.00829%0.29CS..Hα-helixtrans-60.6-43.317700000112.3T310 Y316 V525 D529 K530 G535 V536 Q537T310-A533 HydrophobicContact CG2-CB 3.81Å; Y316-A533 HydrophobicContact CD2-CB 4.43Å; Y316-A533 HydrophobicContact CE2-CB 3.73Å; Y316-A533 PolarHBondContact OH-O 3.4Å; V525-A533 HydrophobicContact CB-CB 4.36Å; V525-A533 HydrophobicContact CG1-CB 3.89Å; V525-A533 HydrophobicContact CG2-CB 3.87Å; D529-A533 WeakPolarHBondContact O-CB 3Å; D529-A533 PolarHBondContact O-N 3.4Å; K530-A533 PolarHBondContact O-N 2.78Å; A533-G535 VanDerWaalsContact C-N 3.3Å; A533-G535 PolarHBondContact O-N 3.46Å; A533-V536 PolarHBondContact O-N 3.19Å; A533-Q537 WeakPolarHBondContact O-CB 3.41Å; A533-Q537 PolarHBondContact O-N 3.38Å
534V80.6Confident82.5Confident21 Ų2152.7 Ų52.713%0.12729%0.291CS..Hα-helixtrans-60-41.9173.6172.80000111.1Y518 L522 K530 F532 Q537 Y538Y518-V534 HydrophobicContact CE2-CG1 4.33Å; Y518-V534 HydrophobicContact CE2-CG2 4.26Å; L522-V534 HydrophobicContact CD2-CG2 3.63Å; K530-V534 WeakPolarHBondContact O-CG2 3.19Å; K530-V534 PolarHBondContact O-N 3.45Å; F532-V534 PolarHBondContact O-N 2.92Å; V534-Q537 WeakPolarHBondContact O-CB 3.05Å; V534-Q537 PolarHBondContact O-N 3.23Å; V534-Y538 HydrophobicContact CG1-CD2 3.75Å; V534-Y538 HydrophobicContact CG1-CE2 3.59Å; V534-Y538 VanDerWaalsContact O-CD2 3.27Å; V534-Y538 WeakPolarHBondContact O-CD2 3.25Å; V534-Y538 PolarHBondContact O-N 2.99Å
535G79.1Confident82.9Confident42 Ų4250.9 Ų50.943%0.43328%0.28SS..Hα-helixtrans-58.7-46.8174.100000113.2S531 F532 A533 Q537 Y538 M539S531-G535 PolarHBondContact O-N 2.79Å; F532-G535 WeakPolarHBondContact O-CA 3.46Å; F532-G535 PolarHBondContact O-N 3.42Å; F532-G535 VanDerWaalsContact O-N 3.11Å; A533-G535 VanDerWaalsContact C-N 3.3Å; A533-G535 PolarHBondContact O-N 3.46Å; G535-Q537 PolarHBondContact O-N 2.84Å; G535-Y538 PolarHBondContact O-N 3.15Å; G535-M539 PolarHBondContact O-N 2.98Å
536V83.2Confident83.3Confident1 Ų153 Ų531%0.00629%0.288CS..Hα-helixtrans-63-40.9176.1173.50000111.4A307 L311 F532 A533 M539 L540A307-V536 HydrophobicContact CB-CG2 4.35Å; L311-V536 HydrophobicContact CD1-CG1 4.49Å; L311-V536 HydrophobicContact CD2-CG1 3.98Å; L311-V536 HydrophobicContact CG-CG1 4.21Å; F532-V536 HydrophobicContact CD1-CG2 4.09Å; F532-V536 HydrophobicContact CE1-CG2 3.55Å; F532-V536 HydrophobicContact CE2-CG2 4.48Å; F532-V536 HydrophobicContact CZ-CG2 3.77Å; F532-V536 WeakPolarHBondContact O-CG2 3.28Å; F532-V536 PolarHBondContact O-N 3.18Å; A533-V536 PolarHBondContact O-N 3.19Å; V536-M539 WeakPolarHBondContact O-CB 3.4Å; V536-M539 PolarHBondContact O-N 3.46Å; V536-L540 HydrophobicContact CG1-CD1 4.26Å; V536-L540 WeakPolarHBondContact O-CG 3.46Å; V536-L540 PolarHBondContact O-N 3.44Å
537Q87.3Confident83.9Confident4 Ų453.1 Ų53.12%0.01929%0.285CS..Hα-helixtrans-58-49.8175.8177.3-167.3-3500111.7Y316 V320 A533 V534 G535 M539 L540 F541Y316-Q537 PolarHBondContact OH-N 2.85Å; V320-Q537 HydrophobicContact CG1-CB 4.44Å; V320-Q537 HydrophobicContact CG1-CG 4.2Å; V320-Q537 HydrophobicContact CG2-CB 4.21Å; V320-Q537 HydrophobicContact CG2-CG 4.1Å; A533-Q537 WeakPolarHBondContact O-CB 3.41Å; A533-Q537 PolarHBondContact O-N 3.38Å; V534-Q537 WeakPolarHBondContact O-CB 3.05Å; V534-Q537 PolarHBondContact O-N 3.23Å; G535-Q537 PolarHBondContact O-N 2.84Å; Q537-M539 VanDerWaalsContact C-N 3.34Å; Q537-M539 PolarHBondContact O-N 3.22Å; Q537-L540 PolarHBondContact O-N 3.41Å; Q537-F541 HydrophobicContact CG-CD1 4.4Å; Q537-F541 HydrophobicContact CG-CE1 3.8Å; Q537-F541 HydrophobicContact CG-CE2 4.31Å; Q537-F541 HydrophobicContact CG-CZ 3.75Å; Q537-F541 WeakPolarHBondContact O-CD1 3.09Å; Q537-F541 PolarHBondContact O-N 3.18Å
538Y85.1Confident84.8Confident106 Ų10650.1 Ų50.142%0.41627%0.265SS..Hα-helixtrans-65.5-36.4178.8-81.7-70.4000112.6V534 G535 L540 F541 R542V534-Y538 HydrophobicContact CG1-CD2 3.75Å; V534-Y538 HydrophobicContact CG1-CE2 3.59Å; V534-Y538 VanDerWaalsContact O-CD2 3.27Å; V534-Y538 WeakPolarHBondContact O-CD2 3.25Å; V534-Y538 PolarHBondContact O-N 2.99Å; G535-Y538 PolarHBondContact O-N 3.15Å; Y538-L540 VanDerWaalsContact C-N 3.32Å; Y538-L540 PolarHBondContact O-N 3.47Å; Y538-F541 HydrophobicContact CD1-CD2 4.09Å; Y538-F541 HydrophobicContact CE1-CD2 4.4Å; Y538-F541 PolarHBondContact O-N 3.21Å; Y538-R542 WeakPolarHBondContact O-CG 3.36Å; Y538-R542 PolarHBondContact O-N 3.15Å; Y538-R542 VanDerWaalsContact O-N 3.08Å
539M84.8Confident85.9Confident60 Ų6042 Ų4230%0.29623%0.227SC..Hα-helixtrans-58.9-45172.3-175.8-174.672.400111F303 G535 V536 Q537 R542 V543F303-M539 HydrophobicContact CE1-SD 4.25Å; F303-M539 HydrophobicContact CZ-SD 4.16Å; G535-M539 PolarHBondContact O-N 2.98Å; V536-M539 WeakPolarHBondContact O-CB 3.4Å; V536-M539 PolarHBondContact O-N 3.46Å; Q537-M539 VanDerWaalsContact C-N 3.34Å; Q537-M539 PolarHBondContact O-N 3.22Å; M539-R542 PolarHBondContact O-N 2.79Å; M539-V543 WeakPolarHBondContact O-CG2 3.17Å; M539-V543 PolarHBondContact O-N 2.82Å; M539-V543 VanDerWaalsContact O-N 3.09Å
540L89.6Confident87Confident27 Ų2740.6 Ų40.614%0.14122%0.22CC..Hα-helixtrans-65.5-37.2176.3-70.7174.5000112.6L311 V320 V324 V536 Q537 Y538 R542 L544L311-L540 HydrophobicContact CD2-CD1 3.85Å; V320-L540 HydrophobicContact CG1-CB 4.34Å; V320-L540 HydrophobicContact CG1-CD1 3.61Å; V324-L540 HydrophobicContact CG2-CB 4.19Å; V536-L540 HydrophobicContact CG1-CD1 4.26Å; V536-L540 WeakPolarHBondContact O-CG 3.46Å; V536-L540 PolarHBondContact O-N 3.44Å; Q537-L540 PolarHBondContact O-N 3.41Å; Y538-L540 VanDerWaalsContact C-N 3.32Å; Y538-L540 PolarHBondContact O-N 3.47Å; L540-R542 VanDerWaalsContact C-N 3.31Å; L540-R542 PolarHBondContact O-N 3.03Å; L540-L544 HydrophobicContact CD2-CD1 3.82Å; L540-L544 HydrophobicContact CD2-CG 4.37Å; L540-L544 VanDerWaalsContact O-CB 3.28Å; L540-L544 WeakPolarHBondContact O-CB 3.42Å; L540-L544 PolarHBondContact O-N 2.94Å
541F90.8Very high88Confident12 Ų1238.2 Ų38.25%0.05321%0.212CC..Hα-helixtrans-58.8-44.2173.3-720000111.5L323 V324 A327 Q537 Y538 A545 F546L323-F541 HydrophobicContact CB-CE1 3.51Å; L323-F541 HydrophobicContact CB-CZ 3.56Å; L323-F541 HydrophobicContact CD1-CZ 4.19Å; L323-F541 HydrophobicContact CG-CZ 4.31Å; V324-F541 HydrophobicContact CG2-CD1 3.81Å; V324-F541 HydrophobicContact CG2-CE1 4.18Å; A327-F541 HydrophobicContact CB-CD1 4.46Å; A327-F541 HydrophobicContact CB-CG 4.41Å; Q537-F541 HydrophobicContact CG-CD1 4.4Å; Q537-F541 HydrophobicContact CG-CE1 3.8Å; Q537-F541 HydrophobicContact CG-CE2 4.31Å; Q537-F541 HydrophobicContact CG-CZ 3.75Å; Q537-F541 WeakPolarHBondContact O-CD1 3.09Å; Q537-F541 PolarHBondContact O-N 3.18Å; Y538-F541 HydrophobicContact CD1-CD2 4.09Å; Y538-F541 HydrophobicContact CE1-CD2 4.4Å; Y538-F541 PolarHBondContact O-N 3.21Å; F541-A545 CarbonylContact O-C 3.14Å; F541-A545 WeakPolarHBondContact O-CA 3.41Å; F541-A545 WeakPolarHBondContact O-CB 3.43Å; F541-A545 PolarHBondContact O-N 2.99Å; F541-F546 HydrophobicContact CB-CD2 4.1Å; F541-F546 HydrophobicContact CB-CE2 3.75Å; F541-F546 HydrophobicContact CB-CZ 4.4Å; F541-F546 HydrophobicContact CD2-CE2 4.39Å; F541-F546 PolarHBondContact O-N 3.39Å
542R90.1Very high89.3Confident30 Ų3037 Ų3711%0.11320%0.197CC..Iπ-helixtrans-65.5-50-179.4-67.5-179-178.4-178.7-4.7112E69 N72 T73 Y538 M539 L540 F546 L547E69-R542 IonicContact OE2-NE 3.53Å; N72-R542 PolarHBondContact ND2-NH2 3.08Å; N72-R542 VanDerWaalsContact ND2-NH2 3.16Å; N72-R542 PolarHBondContact O-NH1 3.44Å; N72-R542 PolarHBondContact OD1-NH1 2.97Å; N72-R542 PolarHBondContact OD1-NH2 2.85Å; T73-R542 WeakPolarHBondContact OG1-CB 3.48Å; T73-R542 WeakPolarHBondContact OG1-CD 3.47Å; Y538-R542 WeakPolarHBondContact O-CG 3.36Å; Y538-R542 PolarHBondContact O-N 3.15Å; Y538-R542 VanDerWaalsContact O-N 3.08Å; M539-R542 PolarHBondContact O-N 2.79Å; L540-R542 VanDerWaalsContact C-N 3.31Å; L540-R542 PolarHBondContact O-N 3.03Å; R542-F546 HydrophobicContact CG-CD2 4.25Å; R542-L547 WeakPolarHBondContact O-CB 3.32Å; R542-L547 PolarHBondContact O-N 3.28Å
543V91Very high90.4Very high72 Ų7235 Ų3544%0.43619%0.188SC..Iπ-helixtrans-74.1-41-173.6178.20000112.2T73 M539 P548T73-V543 HydrophobicContact CG2-CG2 4.11Å; M539-V543 WeakPolarHBondContact O-CG2 3.17Å; M539-V543 PolarHBondContact O-N 2.82Å; M539-V543 VanDerWaalsContact O-N 3.09Å; V543-P548 WeakPolarHBondContact O-CD 3.13Å
544L94.1Very high91.2Very high81 Ų8134.9 Ų34.942%0.42419%0.187SC..Iπ-helixtrans-101.2-15.3-171.9-57.7-178.2000114.3V324 L540 P548V324-L544 HydrophobicContact CG1-CB 3.6Å; V324-L544 HydrophobicContact CG1-CD1 4.46Å; L540-L544 HydrophobicContact CD2-CD1 3.82Å; L540-L544 HydrophobicContact CD2-CG 4.37Å; L540-L544 VanDerWaalsContact O-CB 3.28Å; L540-L544 WeakPolarHBondContact O-CB 3.42Å; L540-L544 PolarHBondContact O-N 2.94Å; L544-P548 WeakPolarHBondContact O-CG 3.35Å
545A95.3Very high92Very high0 Ų036 Ų360%020%0.196CC..Iπ-helixtrans-122-60.4-177.800000113.4V324 A327 A328 F541 G549V324-A545 HydrophobicContact CG1-CB 4.19Å; V324-A545 WeakPolarHBondContact O-CB 3.35Å; A327-A545 HydrophobicContact CB-CB 3.7Å; A328-A545 HydrophobicContact CB-CB 3.8Å; F541-A545 CarbonylContact O-C 3.14Å; F541-A545 WeakPolarHBondContact O-CA 3.41Å; F541-A545 WeakPolarHBondContact O-CB 3.43Å; F541-A545 PolarHBondContact O-N 2.99Å; A545-G549 VanDerWaalsContact O-CA 3.25Å; A545-G549 WeakPolarHBondContact O-CA 3.35Å; A545-G549 PolarHBondContact O-N 3.09Å
546F93.4Very high92.8Very high60 Ų6035.8 Ų35.826%0.26319%0.185SC..Iπ-helixtrans-72.3-35.6-172.1-60.1-44.9000113.1E69 A327 F541 R542 P550E69-F546 HydrophobicContact CG-CB 3.8Å; A327-F546 HydrophobicContact CB-CE1 4.04Å; A327-F546 HydrophobicContact CB-CZ 4.2Å; F541-F546 HydrophobicContact CB-CD2 4.1Å; F541-F546 HydrophobicContact CB-CE2 3.75Å; F541-F546 HydrophobicContact CB-CZ 4.4Å; F541-F546 HydrophobicContact CD2-CE2 4.39Å; F541-F546 PolarHBondContact O-N 3.39Å; R542-F546 HydrophobicContact CG-CD2 4.25Å; F546-P550 WeakPolarHBondContact O-CD 3.39Å
547L93.1Very high93.5Very high66 Ų6635.8 Ų35.835%0.34619%0.185SC..THydrogen-bonded Turntrans-71.3-55.6175.5-167.4158.5000112.5V70 R542 V551V70-L547 HydrophobicContact CG2-CD1 3.85Å; R542-L547 WeakPolarHBondContact O-CB 3.32Å; R542-L547 PolarHBondContact O-N 3.28Å; L547-V551 WeakPolarHBondContact O-CG2 3.45Å
548P95.3Very high93.9Very high36 Ų3636.4 Ų36.423%0.23419%0.188CC..Hα-helixtrans-79.6-27-177.629.7-36.6000114.2V543 L544 V551 L552V543-P548 WeakPolarHBondContact O-CD 3.13Å; L544-P548 WeakPolarHBondContact O-CG 3.35Å; P548-V551 PolarHBondContact O-N 3.05Å; P548-L552 HydrophobicContact CB-CD1 4.39Å; P548-L552 WeakPolarHBondContact O-CB 3.14Å; P548-L552 VanDerWaalsContact O-CG 3.3Å; P548-L552 WeakPolarHBondContact O-CG 3.24Å; P548-L552 PolarHBondContact O-N 3.18Å
549G96Very high94.5Very high0 Ų035 Ų350%019%0.191CC..Hα-helixtrans-55.1-59.7-172.400000113.7A545 V551 L552 Y553A545-G549 VanDerWaalsContact O-CA 3.25Å; A545-G549 WeakPolarHBondContact O-CA 3.35Å; A545-G549 PolarHBondContact O-N 3.09Å; G549-V551 VanDerWaalsContact C-N 3.29Å; G549-V551 PolarHBondContact O-N 2.78Å; G549-L552 PolarHBondContact O-N 3.15Å; G549-Y553 WeakPolarHBondContact O-CD2 3.38Å; G549-Y553 PolarHBondContact O-N 3.13Å; G549-Y553 VanDerWaalsContact O-N 3.12Å
550P96.3Very high95Very high2 Ų232.5 Ų32.51%0.01318%0.179CC..Hα-helixtrans-57.1-39.8175.7-28.138.8000113G62 A66 S331 T335 F336 F546 L552 Y553 G554G62-P550 WeakPolarHBondContact O-CB 3.18Å; A66-P550 HydrophobicContact CB-CB 4.44Å; A66-P550 HydrophobicContact CB-CG 4.24Å; S331-P550 WeakPolarHBondContact OG-CD 3.2Å; S331-P550 WeakPolarHBondContact OG-CG 3.43Å; T335-P550 HydrophobicContact CG2-CB 4.15Å; F336-P550 HydrophobicContact CE2-CB 4.44Å; F336-P550 WeakPolarHBondContact CE2-O 3.21Å; F546-P550 WeakPolarHBondContact O-CD 3.39Å; P550-L552 PolarHBondContact O-N 3.18Å; P550-Y553 PolarHBondContact O-N 3.46Å; P550-G554 PolarHBondContact O-N 3.15Å
551V97.1Very high95.3Very high31 Ų3132.1 Ų32.119%0.18818%0.178CC..Hα-helixtrans-64.1-43.4179.9-175.20000111.6Q59 I63 L547 P548 G549 G554 S555Q59-V551 HydrophobicContact CG-CG1 4.12Å; I63-V551 HydrophobicContact CB-CG2 4.4Å; I63-V551 HydrophobicContact CG1-CG1 4.07Å; I63-V551 HydrophobicContact CG1-CG2 3.69Å; L547-V551 WeakPolarHBondContact O-CG2 3.45Å; P548-V551 PolarHBondContact O-N 3.05Å; G549-V551 VanDerWaalsContact C-N 3.29Å; G549-V551 PolarHBondContact O-N 2.78Å; V551-G554 PolarHBondContact O-N 3.28Å; V551-S555 WeakPolarHBondContact O-CB 3.4Å; V551-S555 PolarHBondContact O-N 3.11Å
552L97.6Very high95.4Very high82 Ų8234 Ų3443%0.42919%0.188SC..Hα-helixtrans-62-48.8177.1-72.8171000111.4P548 G549 P550 G554 S555 I556 L589 F593P548-L552 HydrophobicContact CB-CD1 4.39Å; P548-L552 WeakPolarHBondContact O-CB 3.14Å; P548-L552 VanDerWaalsContact O-CG 3.3Å; P548-L552 WeakPolarHBondContact O-CG 3.24Å; P548-L552 PolarHBondContact O-N 3.18Å; G549-L552 PolarHBondContact O-N 3.15Å; P550-L552 PolarHBondContact O-N 3.18Å; L552-G554 PolarHBondContact O-N 2.89Å; L552-S555 PolarHBondContact O-N 3.26Å; L552-I556 WeakPolarHBondContact O-CG1 3.35Å; L552-I556 PolarHBondContact O-N 3.4Å; L552-L589 HydrophobicContact CB-CD2 4.27Å; L552-F593 HydrophobicContact CD1-CZ 4.19Å
553Y98.1Very high95.4Very high0 Ų033.9 Ų33.90%019%0.19CC..Hα-helixtrans-62.3-42.8176.7-87.6-87.5000112L333 G549 P550 S555 I556 I557 F586 L589 M590 F593L333-Y553 HydrophobicContact CD2-CE1 3.86Å; G549-Y553 WeakPolarHBondContact O-CD2 3.38Å; G549-Y553 PolarHBondContact O-N 3.13Å; G549-Y553 VanDerWaalsContact O-N 3.12Å; P550-Y553 PolarHBondContact O-N 3.46Å; Y553-S555 PolarHBondContact O-N 3.27Å; Y553-I556 PolarHBondContact O-N 2.04Å; Y553-I557 WeakPolarHBondContact O-CD1 3.04Å; Y553-I557 VanDerWaalsContact O-CG1 3.24Å; Y553-I557 WeakPolarHBondContact O-CG1 3.45Å; Y553-I557 PolarHBondContact O-N 2.72Å; Y553-F586 AromaticContact CD1-CD2 3.55Å; Y553-F586 HydrophobicContact CD1-CD2 3.55Å; Y553-F586 HydrophobicContact CD1-CE1 4.48Å; Y553-F586 AromaticContact CD1-CE2 3.32Å; Y553-F586 HydrophobicContact CD1-CE2 3.32Å; Y553-F586 HydrophobicContact CD1-CG 4.24Å; Y553-F586 AromaticContact CD1-CZ 3.83Å; Y553-F586 HydrophobicContact CD1-CZ 3.83Å; Y553-F586 HydrophobicContact CE1-CD1 4.42Å; Y553-F586 HydrophobicContact CE1-CD2 4.05Å; Y553-F586 HydrophobicContact CE1-CE1 4.27Å; Y553-F586 AromaticContact CE1-CE2 3.9Å; Y553-F586 HydrophobicContact CE1-CE2 3.9Å; Y553-F586 HydrophobicContact CE1-CG 4.3Å; Y553-F586 HydrophobicContact CE1-CZ 4Å; Y553-F586 WeakPolarHBondContact CE1-O 3.44Å; Y553-F586 HydrophobicContact CG-CE2 4.31Å; Y553-L589 HydrophobicContact CD1-CD2 4.01Å; Y553-L589 HydrophobicContact CD2-CD2 3.54Å; Y553-L589 HydrophobicContact CE1-CB 4.35Å; Y553-L589 HydrophobicContact CE1-CD2 4.02Å; Y553-L589 HydrophobicContact CE1-CG 4.38Å; Y553-L589 HydrophobicContact CE2-CD2 3.55Å; Y553-L589 HydrophobicContact CE2-CG 4.04Å; Y553-L589 HydrophobicContact CG-CD2 3.82Å; Y553-M590 VanDerWaalsContact OH-CA 3.29Å; Y553-M590 WeakPolarHBondContact OH-CA 2.93Å; Y553-M590 WeakPolarHBondContact OH-CB 3.16Å; Y553-M590 PolarHBondContact OH-N 3.25Å; Y553-F593 HydrophobicContact CE2-CD2 4.22Å; Y553-F593 AromaticContact CE2-CE2 3.79Å; Y553-F593 HydrophobicContact CE2-CE2 3.79Å
554G97.1Very high95.4Very high0 Ų032.9 Ų32.90%018%0.178CC..Hα-helixtrans-58.7-46.3174.600000112.6S58 P550 V551 L552 I556 I557 D558S58-G554 WeakPolarHBondContact CB-O 3.38Å; S58-G554 WeakPolarHBondContact O-CA 3.49Å; P550-G554 PolarHBondContact O-N 3.15Å; V551-G554 PolarHBondContact O-N 3.28Å; L552-G554 PolarHBondContact O-N 2.89Å; G554-I556 VanDerWaalsContact C-N 3.34Å; G554-I556 PolarHBondContact O-N 3.43Å; G554-I557 PolarHBondContact O-N 3.08Å; G554-D558 PolarHBondContact O-N 2.98Å
555S96.9Very high95Very high45 Ų4529.2 Ų29.232%0.31516%0.16SC..Hα-helixtrans-61.4-41.7176.6-176.20000112V551 L552 Y553 I557 D558 T559V551-S555 WeakPolarHBondContact O-CB 3.4Å; V551-S555 PolarHBondContact O-N 3.11Å; L552-S555 PolarHBondContact O-N 3.26Å; Y553-S555 PolarHBondContact O-N 3.27Å; S555-I557 PolarHBondContact O-N 2.93Å; S555-D558 PolarHBondContact O-N 2.93Å; S555-T559 WeakPolarHBondContact O-CG2 3.39Å; S555-T559 PolarHBondContact O-N 3.17Å; S555-T559 VanDerWaalsContact O-N 3.1Å
556I97.5Very high94.3Very high37 Ų3733.3 Ų33.319%0.1918%0.179CC..Hα-helixtrans-61.6-43.8177-74.8-176.8000111.4L552 Y553 G554 D558 T559 R585 L589L552-I556 WeakPolarHBondContact O-CG1 3.35Å; L552-I556 PolarHBondContact O-N 3.4Å; Y553-I556 PolarHBondContact O-N 2.04Å; G554-I556 VanDerWaalsContact C-N 3.34Å; G554-I556 PolarHBondContact O-N 3.43Å; I556-D558 VanDerWaalsContact C-N 3.29Å; I556-D558 PolarHBondContact O-N 3.21Å; I556-T559 PolarHBondContact O-N 3.33Å; I556-T559 PolarHBondContact O-OG1 3.35Å; I556-R585 HydrophobicContact CG2-CB 3.51Å; I556-L589 HydrophobicContact CD1-CB 3.64Å; I556-L589 HydrophobicContact CD1-CD1 4.25Å; I556-L589 HydrophobicContact CD1-CD2 3.44Å; I556-L589 VanDerWaalsContact CD1-CD2 3.44Å; I556-L589 HydrophobicContact CD1-CG 3.94Å
557I97.3Very high93.4Very high0 Ų034.8 Ų34.80%019%0.185CC..Hα-helixtrans-59.4-43.9176.6-64.4160.9000110.3S58 F336 Y553 G554 S555 T559 T560 Y577 F582 F586S58-I557 WeakPolarHBondContact OG-CG2 3.49Å; F336-I557 HydrophobicContact CB-CD1 3.68Å; F336-I557 HydrophobicContact CD1-CD1 3.45Å; F336-I557 VanDerWaalsContact CD1-CD1 3.45Å; F336-I557 HydrophobicContact CD2-CD1 4.17Å; F336-I557 HydrophobicContact CE1-CD1 4.11Å; F336-I557 HydrophobicContact CG-CD1 3.49Å; F336-I557 VanDerWaalsContact CG-CD1 3.49Å; Y553-I557 WeakPolarHBondContact O-CD1 3.04Å; Y553-I557 VanDerWaalsContact O-CG1 3.24Å; Y553-I557 WeakPolarHBondContact O-CG1 3.45Å; Y553-I557 PolarHBondContact O-N 2.72Å; G554-I557 PolarHBondContact O-N 3.08Å; S555-I557 PolarHBondContact O-N 2.93Å; I557-T559 VanDerWaalsContact C-N 3.26Å; I557-T559 PolarHBondContact O-N 2.53Å; I557-T560 PolarHBondContact O-N 3.43Å; I557-T560 VanDerWaalsContact O-N 3.12Å; I557-T560 PolarHBondContact O-OG1 3.03Å; I557-Y577 HydrophobicContact CG2-CD1 4.28Å; I557-Y577 HydrophobicContact CG2-CE1 3.48Å; I557-Y577 VanDerWaalsContact CG2-CE1 3.48Å; I557-Y577 WeakPolarHBondContact O-CE1 3.09Å; I557-F582 HydrophobicContact CB-CE2 4.34Å; I557-F582 HydrophobicContact CD1-CE2 4.42Å; I557-F582 HydrophobicContact CG1-CD2 4.4Å; I557-F582 HydrophobicContact CG1-CE2 3.55Å; I557-F582 HydrophobicContact CG1-CZ 3.98Å; I557-F582 HydrophobicContact CG2-CE2 4.3Å; I557-F582 HydrophobicContact CG2-CZ 4.18Å; I557-F586 HydrophobicContact CD1-CD2 4.26Å; I557-F586 HydrophobicContact CD1-CE2 4.08Å; I557-F586 HydrophobicContact CG1-CD2 4.03Å; I557-F586 HydrophobicContact CG1-CE2 4.37Å
558D96.4Very high92.4Very high18 Ų1835 Ų3510%0.09619%0.191CC..Hα-helixtrans-65-31-179.9-69.9-14.5000111.9S57 S58 Q59 G554 S555 I556 T560 C561 W564S57-D558 WeakPolarHBondContact CB-OD2 3.29Å; S57-D558 PolarHBondContact OG-OD2 2.98Å; S58-D558 WeakPolarHBondContact CA-OD1 3.47Å; S58-D558 WeakPolarHBondContact CB-OD1 3.35Å; S58-D558 PolarHBondContact N-OD1 3.12Å; S58-D558 PolarHBondContact N-OD2 3.24Å; S58-D558 VanDerWaalsContact N-OD2 3.09Å; S58-D558 PolarHBondContact OG-OD1 3.13Å; Q59-D558 WeakPolarHBondContact CB-OD2 3.49Å; Q59-D558 PolarHBondContact N-OD2 3.24Å; G554-D558 PolarHBondContact O-N 2.98Å; S555-D558 PolarHBondContact O-N 2.93Å; I556-D558 VanDerWaalsContact C-N 3.29Å; I556-D558 PolarHBondContact O-N 3.21Å; D558-T560 PolarHBondContact O-N 3.25Å; D558-C561 WeakPolarHBondContact O-CB 3.26Å; D558-C561 PolarHBondContact O-N 3.47Å; D558-W564 HydrophobicContact CB-CH2 3.91Å; D558-W564 HydrophobicContact CB-CZ2 4.17Å; D558-W564 WeakPolarHBondContact O-CZ2 3.03Å
559T96.3Very high91.3Very high77 Ų7736.1 Ų36.147%0.47221%0.21SC..THydrogen-bonded Turntrans-67.3-14.9175.573.30000114.7S555 I556 I557 R585S555-T559 WeakPolarHBondContact O-CG2 3.39Å; S555-T559 PolarHBondContact O-N 3.17Å; S555-T559 VanDerWaalsContact O-N 3.1Å; I556-T559 PolarHBondContact O-N 3.33Å; I556-T559 PolarHBondContact O-OG1 3.35Å; I557-T559 VanDerWaalsContact C-N 3.26Å; I557-T559 PolarHBondContact O-N 2.53Å; T559-R585 VanDerWaalsContact CB-NH1 3.31Å; T559-R585 PolarHBondContact O-NH1 3.46Å; T559-R585 PolarHBondContact OG1-NH1 3.3Å
560T96.1Very high90.4Very high6 Ų640.4 Ų40.44%0.03723%0.23CC..THydrogen-bonded Turntrans-101.61.9-179.169.20000112.5I557 D558 I562 Y577 N578 F582I557-T560 PolarHBondContact O-N 3.43Å; I557-T560 VanDerWaalsContact O-N 3.12Å; I557-T560 PolarHBondContact O-OG1 3.03Å; D558-T560 PolarHBondContact O-N 3.25Å; T560-I562 PolarHBondContact O-N 3.47Å; T560-Y577 WeakPolarHBondContact O-CA 2.93Å; T560-N578 PolarHBondContact O-N 3.37Å; T560-F582 HydrophobicContact CG2-CB 4.23Å
561C94.6Very high89.7Confident19 Ų1948 Ų4813%0.12826%0.258CS..EExtended strand (participates in β ladder)trans-67.1129.2175.9-171.10000111.4D558 L563 W564 C574 Y577D558-C561 WeakPolarHBondContact O-CB 3.26Å; D558-C561 PolarHBondContact O-N 3.47Å; C561-L563 VanDerWaalsContact SG-C 3.52Å; C561-L563 PolarHBondContact SG-O 3.04Å; C561-L563 VanDerWaalsContact SG-O 3.32Å; C561-W564 HydrophobicContact CB-CD2 4.2Å; C561-W564 HydrophobicContact CB-CH2 4.23Å; C561-W564 HydrophobicContact CB-CZ2 3.32Å; C561-W564 PolarHBondContact SG-NE1 3.06Å; C561-W564 VanDerWaalsContact SG-NE1 3.38Å; C561-C574 WeakPolarHBondContact CA-SG 3.4Å; C561-C574 HydrophobicContact CB-CB 3.81Å; C561-C574 WeakPolarHBondContact CB-SG 3.36Å; C561-C574 WeakPolarHBondContact SG-CB 3.2Å; C561-C574 CovalentContact SG-SG 2.02Å; C561-C574 PolarHBondContact SG-SG 2.84Å; C561-Y577 HydrophobicContact CB-CD1 4.39Å; C561-Y577 HydrophobicContact CB-CE1 4.36Å
562I93.1Very high89.2Confident51 Ų5147.6 Ų47.626%0.26226%0.255SS..EExtended strand (participates in β ladder)trans-104.5-28.1176.453.3173.2000112.2T410 V416 Y417 T560 Y576 N578T410-I562 HydrophobicContact CG2-CD1 4.35Å; V416-I562 HydrophobicContact CG1-CB 4.31Å; V416-I562 HydrophobicContact CG1-CD1 4.04Å; V416-I562 HydrophobicContact CG1-CG1 4.12Å; Y417-I562 HydrophobicContact CD2-CD1 4.48Å; Y417-I562 HydrophobicContact CG-CD1 4.24Å; T560-I562 PolarHBondContact O-N 3.47Å; I562-Y576 VanDerWaalsContact CG1-C 3.47Å; I562-Y576 WeakPolarHBondContact CG1-O 3.31Å; I562-Y576 PolarHBondContact N-O 3.16Å; I562-N578 HydrophobicContact CG2-CB 3.73Å
563L90.9Very high88.8Confident29 Ų2944.3 Ų44.315%0.15224%0.24CC..EExtended strand (participates in β ladder)trans-134.1114.1173-173.869.2000110.2V416 R449 C561 C574 L575 Y576V416-L563 HydrophobicContact CG1-CB 3.92Å; V416-L563 HydrophobicContact CG2-CD1 4.4Å; V416-L563 HydrophobicContact CG2-CD2 4.25Å; R449-L563 HydrophobicContact CG-CD2 4.28Å; C561-L563 VanDerWaalsContact SG-C 3.52Å; C561-L563 PolarHBondContact SG-O 3.04Å; C561-L563 VanDerWaalsContact SG-O 3.32Å; L563-C574 PolarHBondContact O-SG 3.03Å; L563-L575 HydrophobicContact CD2-CB 4.38Å; L563-L575 HydrophobicContact CD2-CD1 4.19Å; L563-L575 HydrophobicContact CG-CD1 4.46Å; L563-L575 PolarHBondContact O-N 3.25Å; L563-Y576 HydrophobicContact CB-CD2 4.01Å; L563-Y576 HydrophobicContact CD2-CD2 3.67Å; L563-Y576 HydrophobicContact CD2-CE2 4.09Å; L563-Y576 HydrophobicContact CG-CD2 4.48Å; L563-Y576 PolarHBondContact N-O 3.11Å; L563-Y576 PolarHBondContact O-N 3.48Å
564W91Very high88.6Confident50 Ų5044.8 Ų44.819%0.18924%0.243CC..EExtended strand (participates in β ladder)trans-81.7140.3171.4-71.994.6000110.3D558 C561 R571 T572 C574D558-W564 HydrophobicContact CB-CH2 3.91Å; D558-W564 HydrophobicContact CB-CZ2 4.17Å; D558-W564 WeakPolarHBondContact O-CZ2 3.03Å; C561-W564 HydrophobicContact CB-CD2 4.2Å; C561-W564 HydrophobicContact CB-CH2 4.23Å; C561-W564 HydrophobicContact CB-CZ2 3.32Å; C561-W564 PolarHBondContact SG-NE1 3.06Å; C561-W564 VanDerWaalsContact SG-NE1 3.38Å; W564-R571 HydrophobicContact CB-CG 4.01Å; W564-R571 HydrophobicContact CD2-CG 3.99Å; W564-R571 VanDerWaalsContact CD2-CZ 3.42Å; W564-R571 HydrophobicContact CE3-CG 3.72Å; W564-R571 HydrophobicContact CG-CG 4.08Å; W564-R571 VanDerWaalsContact CG-NE 3.33Å; W564-R571 HydrophobicContact CZ3-CG 4.49Å; W564-R571 VanDerWaalsContact NE1-CZ 3.31Å; W564-R571 VanDerWaalsContact NE1-NH2 3.16Å; W564-T572 WeakPolarHBondContact CZ3-O 3.11Å; W564-C574 HydrophobicContact CD2-CB 4.42Å; W564-C574 HydrophobicContact CE3-CB 4.09Å; W564-C574 HydrophobicContact CH2-CB 4.26Å; W564-C574 HydrophobicContact CZ3-CB 4.04Å
565G85.2Confident88.3Confident4 Ų446.2 Ų46.24%0.04125%0.25CS..EExtended strand (participates in β ladder)trans-69.5151.1165.300000110R571 T572 S573G565-R571 WeakPolarHBondContact O-CA 3.49Å; G565-T572 WeakPolarHBondContact CA-OG1 3.26Å; G565-T572 PolarHBondContact O-N 3.39Å; G565-T572 PolarHBondContact O-OG1 2.85Å; G565-T572 VanDerWaalsContact O-OG1 3.13Å; G565-S573 PolarHBondContact N-O 3.1Å
566E80.9Confident88Confident86 Ų8644.3 Ų44.340%0.40224%0.236SC..EExtended strand (participates in β ladder)trans-132.2132.5176.9-168.2176158.700108D435 G569 Q570D435-E566 WeakPolarHBondContact CB-O 3.47Å; E566-G569 VanDerWaalsContact OE1-CA 3.3Å; E566-G569 WeakPolarHBondContact OE1-CA 3.42Å; E566-Q570 WeakPolarHBondContact CA-O 3.42Å
567K74.5Confident87.8Confident91 Ų9143.2 Ų43.240%0.39623%0.23SC..EExtended strand (participates in β ladder)trans-132.2120.7169.4-72.7-173176.8-172.60107G569 Q570 T572K567-G569 VanDerWaalsContact C-N 3.35Å; K567-G569 PolarHBondContact O-N 2.98Å; K567-Q570 PolarHBondContact N-O 3Å; K567-Q570 WeakPolarHBondContact O-CB 3.04Å; K567-Q570 PolarHBondContact O-N 3.37Å; K567-T572 HydrophobicContact CB-CG2 3.84Å; K567-T572 HydrophobicContact CD-CG2 4.22Å; K567-T572 HydrophobicContact CG-CG2 3.89Å
568C72.6Confident87.7Confident70 Ų7044.9 Ų44.947%0.47324%0.239SC..THydrogen-bonded Turntrans56.241176.7-59.50000115.1C143 Q570C143-C568 HydrophobicContact CB-CB 3.77Å; C143-C568 WeakPolarHBondContact CB-SG 3.46Å; C143-C568 WeakPolarHBondContact SG-CB 3.2Å; C143-C568 CovalentContact SG-SG 2Å; C143-C568 PolarHBondContact SG-SG 2.86Å; C568-Q570 PolarHBondContact O-N 3.16Å
569G71.3Confident87.6Confident60 Ų6044.6 Ų44.662%0.61924%0.237SC*.THydrogen-bonded Turntrans75.92-177.500000114.3E566 K567E566-G569 VanDerWaalsContact OE1-CA 3.3Å; E566-G569 WeakPolarHBondContact OE1-CA 3.42Å; K567-G569 VanDerWaalsContact C-N 3.35Å; K567-G569 PolarHBondContact O-N 2.98Å
570Q76.9Confident87.5Confident90 Ų9042.8 Ų42.842%0.42123%0.225SC..EExtended strand (participates in β ladder)trans-109.1135.2178-63.5-172.83.700111.4E566 K567 C568 T572E566-Q570 WeakPolarHBondContact CA-O 3.42Å; K567-Q570 PolarHBondContact N-O 3Å; K567-Q570 WeakPolarHBondContact O-CB 3.04Å; K567-Q570 PolarHBondContact O-N 3.37Å; C568-Q570 PolarHBondContact O-N 3.16Å; Q570-T572 PolarHBondContact O-N 2.9Å
571R83.4Confident87.4Confident163 Ų16343.3 Ų43.362%0.61523%0.231SC*.EExtended strand (participates in β ladder)trans-70125.9176.8175.3164.5161.2-177.7-7.4111.1W564 G565W564-R571 HydrophobicContact CB-CG 4.01Å; W564-R571 HydrophobicContact CD2-CG 3.99Å; W564-R571 VanDerWaalsContact CD2-CZ 3.42Å; W564-R571 HydrophobicContact CE3-CG 3.72Å; W564-R571 HydrophobicContact CG-CG 4.08Å; W564-R571 VanDerWaalsContact CG-NE 3.33Å; W564-R571 HydrophobicContact CZ3-CG 4.49Å; W564-R571 VanDerWaalsContact NE1-CZ 3.31Å; W564-R571 VanDerWaalsContact NE1-NH2 3.16Å; G565-R571 WeakPolarHBondContact O-CA 3.49Å
572T86.4Confident87.5Confident21 Ų2142.4 Ų42.413%0.12923%0.225CC..EExtended strand (participates in β ladder)trans-106.6-157.5179.765.50000111.6G55 W564 G565 K567 Q570G55-T572 CarbonylContact O-C 3.57Å; G55-T572 VanDerWaalsContact O-C 3.27Å; G55-T572 WeakPolarHBondContact O-CA 3.4Å; W564-T572 WeakPolarHBondContact CZ3-O 3.11Å; G565-T572 WeakPolarHBondContact CA-OG1 3.26Å; G565-T572 PolarHBondContact O-N 3.39Å; G565-T572 PolarHBondContact O-OG1 2.85Å; G565-T572 VanDerWaalsContact O-OG1 3.13Å; K567-T572 HydrophobicContact CB-CG2 3.84Å; K567-T572 HydrophobicContact CD-CG2 4.22Å; K567-T572 HydrophobicContact CG-CG2 3.89Å; Q570-T572 PolarHBondContact O-N 2.9Å
573S89.3Confident87.6Confident14 Ų1440.8 Ų40.810%0.09822%0.215CC..EExtended strand (participates in β ladder)trans-60.9149.617457.80000111.2E51 G55 L56 G565E51-S573 WeakPolarHBondContact O-CB 3.49Å; G55-S573 VanDerWaalsContact C-N 3.34Å; G55-S573 PolarHBondContact O-N 3.39Å; L56-S573 WeakPolarHBondContact O-CB 3.28Å; G565-S573 PolarHBondContact N-O 3.1Å
574C92.6Very high87.9Confident9 Ų945.3 Ų45.36%0.06123%0.234CC..EExtended strand (participates in β ladder)trans-67.4134.4175.6-176.10000111.6C561 L563 W564 Y576 Y577C561-C574 WeakPolarHBondContact CA-SG 3.4Å; C561-C574 HydrophobicContact CB-CB 3.81Å; C561-C574 WeakPolarHBondContact CB-SG 3.36Å; C561-C574 WeakPolarHBondContact SG-CB 3.2Å; C561-C574 CovalentContact SG-SG 2.02Å; C561-C574 PolarHBondContact SG-SG 2.84Å; L563-C574 PolarHBondContact O-SG 3.03Å; W564-C574 HydrophobicContact CD2-CB 4.42Å; W564-C574 HydrophobicContact CE3-CB 4.09Å; W564-C574 HydrophobicContact CH2-CB 4.26Å; W564-C574 HydrophobicContact CZ3-CB 4.04Å; C574-Y576 PolarHBondContact SG-O 3.15Å; C574-Y577 HydrophobicContact CB-CE1 3.76Å; C574-Y577 HydrophobicContact CB-CE2 3.94Å; C574-Y577 VanDerWaalsContact CB-CZ 3.43Å; C574-Y577 WeakPolarHBondContact CB-OH 3.11Å; C574-Y577 VanDerWaalsContact SG-CE1 3.57Å
575L90.3Very high88.2Confident31 Ų3149 Ų4916%0.16225%0.248CC..EExtended strand (participates in β ladder)trans-91-47.6-179.3-62172.5000111.2F437 L563F437-L575 HydrophobicContact CB-CD1 4.43Å; F437-L575 HydrophobicContact CD1-CD2 3.99Å; F437-L575 HydrophobicContact CD2-CB 4.37Å; F437-L575 HydrophobicContact CD2-CD1 3.63Å; F437-L575 HydrophobicContact CD2-CD2 4.26Å; F437-L575 HydrophobicContact CD2-CG 4.3Å; F437-L575 HydrophobicContact CE1-CD2 3.97Å; F437-L575 HydrophobicContact CE2-CB 3.86Å; F437-L575 HydrophobicContact CE2-CD1 4Å; F437-L575 HydrophobicContact CE2-CD2 4.25Å; F437-L575 HydrophobicContact CE2-CG 4.25Å; F437-L575 HydrophobicContact CG-CD1 4.01Å; F437-L575 HydrophobicContact CG-CD2 4.13Å; F437-L575 HydrophobicContact CZ-CB 4.08Å; F437-L575 HydrophobicContact CZ-CD2 4.11Å; L563-L575 HydrophobicContact CD2-CB 4.38Å; L563-L575 HydrophobicContact CD2-CD1 4.19Å; L563-L575 HydrophobicContact CG-CD1 4.46Å; L563-L575 PolarHBondContact O-N 3.25Å
576Y91.7Very high88.8Confident5 Ų548.8 Ų48.82%0.0225%0.246CC..EExtended strand (participates in β ladder)trans-124.4140.6177.5-68.4-63.4000112.5L236 V413 F437 E447 I562 L563 C574L236-Y576 HydrophobicContact CD1-CE1 3.99Å; V413-Y576 HydrophobicContact CG1-CD2 4.22Å; V413-Y576 HydrophobicContact CG1-CE2 3.82Å; V413-Y576 HydrophobicContact CG2-CD1 4.24Å; V413-Y576 HydrophobicContact CG2-CD2 4.42Å; V413-Y576 HydrophobicContact CG2-CE1 4.16Å; V413-Y576 HydrophobicContact CG2-CE2 4.34Å; V413-Y576 HydrophobicContact CG2-CG 4.37Å; F437-Y576 HydrophobicContact CE2-CD2 4.49Å; F437-Y576 AromaticContact CE2-CE2 3.79Å; F437-Y576 HydrophobicContact CE2-CE2 3.79Å; F437-Y576 HydrophobicContact CZ-CE2 4.5Å; E447-Y576 WeakPolarHBondContact OE1-CE1 3.35Å; E447-Y576 PolarHBondContact OE1-OH 2.81Å; I562-Y576 VanDerWaalsContact CG1-C 3.47Å; I562-Y576 WeakPolarHBondContact CG1-O 3.31Å; I562-Y576 PolarHBondContact N-O 3.16Å; L563-Y576 HydrophobicContact CB-CD2 4.01Å; L563-Y576 HydrophobicContact CD2-CD2 3.67Å; L563-Y576 HydrophobicContact CD2-CE2 4.09Å; L563-Y576 HydrophobicContact CG-CD2 4.48Å; L563-Y576 PolarHBondContact N-O 3.11Å; L563-Y576 PolarHBondContact O-N 3.48Å; C574-Y576 PolarHBondContact SG-O 3.15Å
577Y93.7Very high89.5Confident13 Ų1344.7 Ų44.75%0.05123%0.227CC..EExtended strand (participates in β ladder)trans-116.4145178.2-66.1-87.7000110.7K339 K343 I557 T560 C561 C574 L579 F582K339-Y577 VanDerWaalsContact CE-OH 3.3Å; K339-Y577 WeakPolarHBondContact CE-OH 3.5Å; K339-Y577 PolarHBondContact NZ-OH 3.26Å; K343-Y577 HydrophobicContact CD-CD2 4.47Å; K343-Y577 HydrophobicContact CG-CD2 4.36Å; K343-Y577 HydrophobicContact CG-CE2 4.45Å; I557-Y577 HydrophobicContact CG2-CD1 4.28Å; I557-Y577 HydrophobicContact CG2-CE1 3.48Å; I557-Y577 VanDerWaalsContact CG2-CE1 3.48Å; I557-Y577 WeakPolarHBondContact O-CE1 3.09Å; T560-Y577 WeakPolarHBondContact O-CA 2.93Å; C561-Y577 HydrophobicContact CB-CD1 4.39Å; C561-Y577 HydrophobicContact CB-CE1 4.36Å; C574-Y577 HydrophobicContact CB-CE1 3.76Å; C574-Y577 HydrophobicContact CB-CE2 3.94Å; C574-Y577 VanDerWaalsContact CB-CZ 3.43Å; C574-Y577 WeakPolarHBondContact CB-OH 3.11Å; C574-Y577 VanDerWaalsContact SG-CE1 3.57Å; Y577-L579 PolarHBondContact O-N 3.22Å; Y577-L579 VanDerWaalsContact O-N 3.1Å; Y577-F582 HydrophobicContact CG-CD1 4.46Å
578N94.6Very high90.6Very high35 Ų3541.3 Ų41.319%0.18722%0.218CC..  trans-69.7101162.2-174.3-50.5000108.2T410 Y417 T560 I562 D580 G581 F582T410-N578 PolarHBondContact OG1-OD1 3.2Å; Y417-N578 WeakPolarHBondContact CE2-ND2 3.42Å; Y417-N578 PolarHBondContact OH-ND2 3.15Å; T560-N578 PolarHBondContact O-N 3.37Å; I562-N578 HydrophobicContact CG2-CB 3.73Å; N578-D580 VanDerWaalsContact C-N 3.31Å; N578-D580 PolarHBondContact O-N 3.25Å; N578-D580 PolarHBondContact OD1-N 3.49Å; N578-G581 PolarHBondContact O-N 2.99Å; N578-G581 PolarHBondContact OD1-N 3.33Å; N578-F582 WeakPolarHBondContact O-CB 3.46Å; N578-F582 PolarHBondContact O-N 3.17Å
579L93.9Very high91.8Very high13 Ų1339.2 Ų39.27%0.06820%0.202CC..Hα-helixtrans-65.4-33.4-174-60.9-176.1000112.4Q344 C408 T410 Y577 F582 R583Q344-L579 PolarHBondContact OE1-O 2.92Å; C408-L579 HydrophobicContact CB-CD1 4.21Å; T410-L579 PolarHBondContact OG1-N 2.91Å; Y577-L579 PolarHBondContact O-N 3.22Å; Y577-L579 VanDerWaalsContact O-N 3.1Å; L579-F582 HydrophobicContact CD2-CD1 4.48Å; L579-F582 PolarHBondContact O-N 2.02Å; L579-R583 WeakPolarHBondContact O-CB 3.33Å; L579-R583 PolarHBondContact O-N 2.83Å
580D94Very high93Very high39 Ų3936.6 Ų36.621%0.20917%0.173CC..Hα-helixtrans-69.8-44.6178.4-65.2-65.1000111.7T410 N578 F582 R583 K584T410-D580 PolarHBondContact N-OD2 2.9Å; T410-D580 PolarHBondContact OG1-N 3.29Å; T410-D580 VanDerWaalsContact OG1-N 3.16Å; T410-D580 PolarHBondContact OG1-OD2 3.28Å; N578-D580 VanDerWaalsContact C-N 3.31Å; N578-D580 PolarHBondContact O-N 3.25Å; N578-D580 PolarHBondContact OD1-N 3.49Å; D580-F582 VanDerWaalsContact C-N 3.34Å; D580-R583 IonicContact OD1-CZ 3.91Å; D580-R583 IonicContact OD1-NH1 3.56Å; D580-R583 IonicContact OD1-NH2 3.11Å; D580-R583 PolarHBondContact OD1-NH2 2.87Å; D580-R583 VanDerWaalsContact OD1-NH2 3.11Å; D580-K584 WeakPolarHBondContact O-CB 3.4Å; D580-K584 WeakPolarHBondContact O-CD 3.33Å; D580-K584 WeakPolarHBondContact O-CG 3.21Å; D580-K584 PolarHBondContact O-N 3.08Å; D580-K584 VanDerWaalsContact O-N 3.15Å
581G95.6Very high94Very high16 Ų1633.3 Ų33.317%0.16516%0.159CC..Hα-helixtrans-64.6-40.1171.800000111.7N578 K584 R585N578-G581 PolarHBondContact O-N 2.99Å; N578-G581 PolarHBondContact OD1-N 3.33Å; G581-K584 PolarHBondContact O-N 3.33Å; G581-R585 WeakPolarHBondContact O-CB 3.27Å; G581-R585 VanDerWaalsContact O-CG 3.32Å; G581-R585 WeakPolarHBondContact O-CG 3.39Å; G581-R585 PolarHBondContact O-N 3.07Å
582F95.9Very high94.6Very high0 Ų029.9 Ų29.90%016%0.156CC..Hα-helixtrans-62.3-53.5-179.5-173.9-169.6000110.5F340 K343 I557 T560 Y577 N578 L579 D580 K584 R585 F586F340-F582 HydrophobicContact CB-CZ 4.33Å; F340-F582 HydrophobicContact CD2-CD2 4.23Å; F340-F582 HydrophobicContact CD2-CE1 4.28Å; F340-F582 AromaticContact CD2-CE2 3.72Å; F340-F582 HydrophobicContact CD2-CE2 3.72Å; F340-F582 AromaticContact CD2-CZ 3.78Å; F340-F582 HydrophobicContact CD2-CZ 3.78Å; F340-F582 HydrophobicContact CE2-CD2 4.44Å; F340-F582 HydrophobicContact CE2-CE2 4.36Å; K343-F582 HydrophobicContact CB-CE1 4Å; I557-F582 HydrophobicContact CB-CE2 4.34Å; I557-F582 HydrophobicContact CD1-CE2 4.42Å; I557-F582 HydrophobicContact CG1-CD2 4.4Å; I557-F582 HydrophobicContact CG1-CE2 3.55Å; I557-F582 HydrophobicContact CG1-CZ 3.98Å; I557-F582 HydrophobicContact CG2-CE2 4.3Å; I557-F582 HydrophobicContact CG2-CZ 4.18Å; T560-F582 HydrophobicContact CG2-CB 4.23Å; Y577-F582 HydrophobicContact CG-CD1 4.46Å; N578-F582 WeakPolarHBondContact O-CB 3.46Å; N578-F582 PolarHBondContact O-N 3.17Å; L579-F582 HydrophobicContact CD2-CD1 4.48Å; L579-F582 PolarHBondContact O-N 2.02Å; D580-F582 VanDerWaalsContact C-N 3.34Å; F582-K584 PolarHBondContact O-N 3.02Å; F582-R585 PolarHBondContact O-N 2.94Å; F582-F586 HydrophobicContact CD2-CB 3.91Å; F582-F586 HydrophobicContact CD2-CG 4.48Å; F582-F586 HydrophobicContact CE2-CB 3.89Å; F582-F586 AromaticContact CE2-CD2 3.78Å; F582-F586 HydrophobicContact CE2-CD2 3.78Å; F582-F586 AromaticContact CE2-CG 3.96Å; F582-F586 HydrophobicContact CE2-CG 3.96Å; F582-F586 WeakPolarHBondContact O-CB 3.47Å; F582-F586 PolarHBondContact O-N 2.96Å
583R95.6Very high95.2Very high17 Ų1730 Ų306%0.06416%0.155CC..Hα-helixtrans-54.6-50.8174.9-175.3173.164.4-108.20.1112.5F340 I404 I406 G407 C408 L579 D580 L587F340-R583 HydrophobicContact CE2-CB 4.39Å; F340-R583 HydrophobicContact CZ-CB 4.27Å; F340-R583 HydrophobicContact CZ-CG 4.15Å; I404-R583 VanDerWaalsContact O-CD 3.24Å; I404-R583 WeakPolarHBondContact O-CD 3.26Å; I404-R583 WeakPolarHBondContact O-CG 3.43Å; I404-R583 PolarHBondContact O-NE 3.25Å; I406-R583 WeakPolarHBondContact O-CD 3.28Å; G407-R583 VanDerWaalsContact C-NH1 3.33Å; G407-R583 PolarHBondContact O-NH1 3.33Å; C408-R583 PolarHBondContact O-NH1 3.07Å; L579-R583 WeakPolarHBondContact O-CB 3.33Å; L579-R583 PolarHBondContact O-N 2.83Å; D580-R583 IonicContact OD1-CZ 3.91Å; D580-R583 IonicContact OD1-NH1 3.56Å; D580-R583 IonicContact OD1-NH2 3.11Å; D580-R583 PolarHBondContact OD1-NH2 2.87Å; D580-R583 VanDerWaalsContact OD1-NH2 3.11Å; R583-L587 HydrophobicContact CG-CD1 3.78Å; R583-L587 WeakPolarHBondContact O-CB 3.4Å; R583-L587 PolarHBondContact O-N 2.85Å
584K96.1Very high95.5Very high125 Ų12529.3 Ų29.354%0.54315%0.15SC..Hα-helixtrans-63.3-44.8-177.2-71.6171.1-173.7175.50112.9I404 D580 G581 F582 G588I404-K584 HydrophobicContact CG2-CG 4.21Å; D580-K584 WeakPolarHBondContact O-CB 3.4Å; D580-K584 WeakPolarHBondContact O-CD 3.33Å; D580-K584 WeakPolarHBondContact O-CG 3.21Å; D580-K584 PolarHBondContact O-N 3.08Å; D580-K584 VanDerWaalsContact O-N 3.15Å; G581-K584 PolarHBondContact O-N 3.33Å; F582-K584 PolarHBondContact O-N 3.02Å; K584-G588 WeakPolarHBondContact O-CA 3.27Å; K584-G588 PolarHBondContact O-N 3.21Å
585R97.4Very high95.8Very high126 Ų12631.6 Ų31.648%0.47517%0.166SC..Hα-helixtrans-77.1-41.5-177.6-63.4179.7-175.9165.74.6112.1I556 T559 G581 F582 L589I556-R585 HydrophobicContact CG2-CB 3.51Å; T559-R585 VanDerWaalsContact CB-NH1 3.31Å; T559-R585 PolarHBondContact O-NH1 3.46Å; T559-R585 PolarHBondContact OG1-NH1 3.3Å; G581-R585 WeakPolarHBondContact O-CB 3.27Å; G581-R585 VanDerWaalsContact O-CG 3.32Å; G581-R585 WeakPolarHBondContact O-CG 3.39Å; G581-R585 PolarHBondContact O-N 3.07Å; F582-R585 PolarHBondContact O-N 2.94Å; R585-L589 PolarHBondContact O-N 3.13Å
586F97.5Very high96.1Very high0 Ų031 Ų310%017%0.167CC..Hα-helixtrans-67-51.9-179-174.5-91.2000112L333 F336 M337 F340 Y553 I557 F582 L589 M590L333-F586 HydrophobicContact CD2-CE1 3.7Å; L333-F586 HydrophobicContact CD2-CZ 3.97Å; F336-F586 HydrophobicContact CB-CE2 3.69Å; F336-F586 HydrophobicContact CB-CZ 4.03Å; M337-F586 HydrophobicContact CE-CE1 4.3Å; M337-F586 HydrophobicContact SD-CE1 4.01Å; F340-F586 HydrophobicContact CB-CD1 4.36Å; F340-F586 HydrophobicContact CB-CE1 3.94Å; F340-F586 HydrophobicContact CB-CZ 4.11Å; F340-F586 HydrophobicContact CD2-CB 4.17Å; F340-F586 AromaticContact CD2-CD1 3.48Å; F340-F586 HydrophobicContact CD2-CD1 3.48Å; F340-F586 VanDerWaalsContact CD2-CD1 3.48Å; F340-F586 HydrophobicContact CD2-CD2 4.48Å; F340-F586 AromaticContact CD2-CE1 3.94Å; F340-F586 HydrophobicContact CD2-CE1 3.94Å; F340-F586 AromaticContact CD2-CG 3.81Å; F340-F586 HydrophobicContact CD2-CG 3.81Å; F340-F586 HydrophobicContact CE2-CB 4.2Å; F340-F586 AromaticContact CE2-CD1 3.92Å; F340-F586 HydrophobicContact CE2-CD1 3.92Å; F340-F586 HydrophobicContact CE2-CG 4.26Å; F340-F586 AromaticContact CG-CD1 3.92Å; F340-F586 HydrophobicContact CG-CD1 3.92Å; F340-F586 AromaticContact CG-CE1 3.9Å; F340-F586 HydrophobicContact CG-CE1 3.9Å; Y553-F586 AromaticContact CD1-CD2 3.55Å; Y553-F586 HydrophobicContact CD1-CD2 3.55Å; Y553-F586 HydrophobicContact CD1-CE1 4.48Å; Y553-F586 AromaticContact CD1-CE2 3.32Å; Y553-F586 HydrophobicContact CD1-CE2 3.32Å; Y553-F586 HydrophobicContact CD1-CG 4.24Å; Y553-F586 AromaticContact CD1-CZ 3.83Å; Y553-F586 HydrophobicContact CD1-CZ 3.83Å; Y553-F586 HydrophobicContact CE1-CD1 4.42Å; Y553-F586 HydrophobicContact CE1-CD2 4.05Å; Y553-F586 HydrophobicContact CE1-CE1 4.27Å; Y553-F586 AromaticContact CE1-CE2 3.9Å; Y553-F586 HydrophobicContact CE1-CE2 3.9Å; Y553-F586 HydrophobicContact CE1-CG 4.3Å; Y553-F586 HydrophobicContact CE1-CZ 4Å; Y553-F586 WeakPolarHBondContact CE1-O 3.44Å; Y553-F586 HydrophobicContact CG-CE2 4.31Å; I557-F586 HydrophobicContact CD1-CD2 4.26Å; I557-F586 HydrophobicContact CD1-CE2 4.08Å; I557-F586 HydrophobicContact CG1-CD2 4.03Å; I557-F586 HydrophobicContact CG1-CE2 4.37Å; F582-F586 HydrophobicContact CD2-CB 3.91Å; F582-F586 HydrophobicContact CD2-CG 4.48Å; F582-F586 HydrophobicContact CE2-CB 3.89Å; F582-F586 AromaticContact CE2-CD2 3.78Å; F582-F586 HydrophobicContact CE2-CD2 3.78Å; F582-F586 AromaticContact CE2-CG 3.96Å; F582-F586 HydrophobicContact CE2-CG 3.96Å; F582-F586 WeakPolarHBondContact O-CB 3.47Å; F582-F586 PolarHBondContact O-N 2.96Å; F586-L589 PolarHBondContact O-N 3.47Å; F586-M590 PolarHBondContact O-N 3.45Å
587L97.3Very high96.4Very high1 Ų130.8 Ų30.81%0.00517%0.167CC..Hα-helixtrans-76-26.7177.3-60.2175.7000111.9F340 M403 I404 F499 R583 M590 V591F340-L587 HydrophobicContact CE1-CD1 4.45Å; F340-L587 HydrophobicContact CE2-CG 4.49Å; F340-L587 HydrophobicContact CZ-CD1 3.97Å; F340-L587 HydrophobicContact CZ-CG 4.13Å; M403-L587 HydrophobicContact CB-CD1 3.93Å; M403-L587 WeakPolarHBondContact O-CD1 3.5Å; I404-L587 HydrophobicContact CG1-CB 3.85Å; F499-L587 HydrophobicContact CE2-CD1 4Å; R583-L587 HydrophobicContact CG-CD1 3.78Å; R583-L587 WeakPolarHBondContact O-CB 3.4Å; R583-L587 PolarHBondContact O-N 2.85Å; L587-M590 HydrophobicContact CD2-SD 4.31Å; L587-M590 VanDerWaalsContact O-CB 3.29Å; L587-M590 WeakPolarHBondContact O-CB 3.43Å; L587-M590 PolarHBondContact O-N 2.86Å; L587-V591 PolarHBondContact O-N 1.99Å
588G96.9Very high96.6Very high20 Ų2031.2 Ų31.221%0.20617%0.17CC..Hα-helixtrans-60.7-44.217000000112.3K584 M590 V591 V592K584-G588 WeakPolarHBondContact O-CA 3.27Å; K584-G588 PolarHBondContact O-N 3.21Å; G588-M590 VanDerWaalsContact C-N 3.26Å; G588-M590 PolarHBondContact O-N 3.12Å; G588-V591 PolarHBondContact O-N 3.08Å; G588-V591 VanDerWaalsContact O-N 3.1Å; G588-V592 WeakPolarHBondContact O-CG2 3.22Å; G588-V592 PolarHBondContact O-N 2.95Å
589L97.4Very high96.7Very high26 Ų2634.4 Ų34.414%0.13619%0.186CC..Hα-helixtrans-60.8-37.8173.8-179.262.3000111.6L552 Y553 I556 R585 F586 V591 V592 F593L552-L589 HydrophobicContact CB-CD2 4.27Å; Y553-L589 HydrophobicContact CD1-CD2 4.01Å; Y553-L589 HydrophobicContact CD2-CD2 3.54Å; Y553-L589 HydrophobicContact CE1-CB 4.35Å; Y553-L589 HydrophobicContact CE1-CD2 4.02Å; Y553-L589 HydrophobicContact CE1-CG 4.38Å; Y553-L589 HydrophobicContact CE2-CD2 3.55Å; Y553-L589 HydrophobicContact CE2-CG 4.04Å; Y553-L589 HydrophobicContact CG-CD2 3.82Å; I556-L589 HydrophobicContact CD1-CB 3.64Å; I556-L589 HydrophobicContact CD1-CD1 4.25Å; I556-L589 HydrophobicContact CD1-CD2 3.44Å; I556-L589 VanDerWaalsContact CD1-CD2 3.44Å; I556-L589 HydrophobicContact CD1-CG 3.94Å; R585-L589 PolarHBondContact O-N 3.13Å; F586-L589 PolarHBondContact O-N 3.47Å; L589-V591 PolarHBondContact O-N 3.11Å; L589-V592 WeakPolarHBondContact O-CB 3.21Å; L589-V592 PolarHBondContact O-N 2.03Å; L589-F593 HydrophobicContact CD1-CD2 4.19Å; L589-F593 HydrophobicContact CD1-CE2 3.69Å; L589-F593 HydrophobicContact CD1-CZ 4.17Å; L589-F593 HydrophobicContact CD2-CE2 3.96Å; L589-F593 HydrophobicContact CG-CD2 4.04Å; L589-F593 HydrophobicContact CG-CE2 3.63Å; L589-F593 VanDerWaalsContact O-CD2 3.31Å; L589-F593 WeakPolarHBondContact O-CD2 3.43Å; L589-F593 PolarHBondContact O-N 3.18Å; L589-F593 VanDerWaalsContact O-N 3.12Å
590M96.8Very high96.9Very high4 Ų434.5 Ų34.52%0.0219%0.187CC..Hα-helixtrans-58-48.2172.4153174.7-161.200111.4L329 L333 A400 M403 T506 I510 Y553 F586 L587 G588 V592 F593 V594L329-M590 HydrophobicContact CD1-CB 3.55Å; L329-M590 HydrophobicContact CD1-CG 3.53Å; L329-M590 HydrophobicContact CD1-SD 4.39Å; L333-M590 HydrophobicContact CD1-CE 4.28Å; L333-M590 HydrophobicContact CD1-SD 3.91Å; A400-M590 HydrophobicContact CB-CE 3.96Å; M403-M590 HydrophobicContact CE-CE 3.66Å; M403-M590 HydrophobicContact CE-SD 3.93Å; T506-M590 HydrophobicContact CG2-CE 3.24Å; I510-M590 HydrophobicContact CD1-CE 4.39Å; Y553-M590 VanDerWaalsContact OH-CA 3.29Å; Y553-M590 WeakPolarHBondContact OH-CA 2.93Å; Y553-M590 WeakPolarHBondContact OH-CB 3.16Å; Y553-M590 PolarHBondContact OH-N 3.25Å; F586-M590 PolarHBondContact O-N 3.45Å; L587-M590 HydrophobicContact CD2-SD 4.31Å; L587-M590 VanDerWaalsContact O-CB 3.29Å; L587-M590 WeakPolarHBondContact O-CB 3.43Å; L587-M590 PolarHBondContact O-N 2.86Å; G588-M590 VanDerWaalsContact C-N 3.26Å; G588-M590 PolarHBondContact O-N 3.12Å; M590-V592 VanDerWaalsContact C-N 3.31Å; M590-V592 PolarHBondContact O-N 3.45Å; M590-F593 PolarHBondContact O-N 3.47Å; M590-V594 WeakPolarHBondContact O-CG2 3.32Å; M590-V594 PolarHBondContact O-N 3.43Å; M590-V594 VanDerWaalsContact O-N 3.09Å
591V96.9Very high97Very high22 Ų2232.7 Ų32.713%0.13318%0.178CC..Hα-helixtrans-62.3-37.8177.4172.60000111.7L397 A400 L401 I404 L587 G588 L589 F593 V594 C595L397-V591 HydrophobicContact CD2-CG1 4.09Å; A400-V591 HydrophobicContact CB-CG2 4.48Å; L401-V591 HydrophobicContact CD2-CG1 4.12Å; L401-V591 HydrophobicContact CD2-CG2 4.14Å; I404-V591 HydrophobicContact CD1-CG2 3.95Å; L587-V591 PolarHBondContact O-N 1.99Å; G588-V591 PolarHBondContact O-N 3.08Å; G588-V591 VanDerWaalsContact O-N 3.1Å; L589-V591 PolarHBondContact O-N 3.11Å; V591-F593 PolarHBondContact O-N 2.75Å; V591-V594 PolarHBondContact O-N 3.39Å; V591-C595 WeakPolarHBondContact O-CB 3.48Å; V591-C595 PolarHBondContact O-N 2.95Å; V591-C595 PolarHBondContact O-SG 2.65Å; V591-C595 VanDerWaalsContact O-SG 3.34Å
592V97.4Very high97.1Very high91 Ų9135.8 Ų35.855%0.55219%0.19SC*.Hα-helixtrans-58.3-47.8175.7169.90000111.4G588 L589 M590 V594 C595 G596G588-V592 WeakPolarHBondContact O-CG2 3.22Å; G588-V592 PolarHBondContact O-N 2.95Å; L589-V592 WeakPolarHBondContact O-CB 3.21Å; L589-V592 PolarHBondContact O-N 2.03Å; M590-V592 VanDerWaalsContact C-N 3.31Å; M590-V592 PolarHBondContact O-N 3.45Å; V592-V594 PolarHBondContact O-N 2.89Å; V592-C595 PolarHBondContact O-N 3.22Å; V592-G596 PolarHBondContact O-N 3.17Å
593F97.6Very high97.1Very high23 Ų2339.5 Ų39.510%0.10121%0.209CC..Hα-helixtrans-63.8-40.1176.6-74.1-57.8000112.4N325 A328 L329 L552 Y553 L589 M590 V591 G596 A597N325-F593 HydrophobicContact CB-CD1 4.45Å; N325-F593 WeakPolarHBondContact CB-O 3.01Å; A328-F593 HydrophobicContact CB-CD1 4.01Å; A328-F593 HydrophobicContact CB-CE1 3.62Å; A328-F593 HydrophobicContact CB-CE2 4.35Å; A328-F593 HydrophobicContact CB-CZ 3.81Å; L329-F593 HydrophobicContact CB-CB 3.94Å; L329-F593 HydrophobicContact CB-CD2 4.33Å; L329-F593 HydrophobicContact CB-CG 4.34Å; L552-F593 HydrophobicContact CD1-CZ 4.19Å; Y553-F593 HydrophobicContact CE2-CD2 4.22Å; Y553-F593 AromaticContact CE2-CE2 3.79Å; Y553-F593 HydrophobicContact CE2-CE2 3.79Å; L589-F593 HydrophobicContact CD1-CD2 4.19Å; L589-F593 HydrophobicContact CD1-CE2 3.69Å; L589-F593 HydrophobicContact CD1-CZ 4.17Å; L589-F593 HydrophobicContact CD2-CE2 3.96Å; L589-F593 HydrophobicContact CG-CD2 4.04Å; L589-F593 HydrophobicContact CG-CE2 3.63Å; L589-F593 VanDerWaalsContact O-CD2 3.31Å; L589-F593 WeakPolarHBondContact O-CD2 3.43Å; L589-F593 PolarHBondContact O-N 3.18Å; L589-F593 VanDerWaalsContact O-N 3.12Å; M590-F593 PolarHBondContact O-N 3.47Å; V591-F593 PolarHBondContact O-N 2.75Å; F593-G596 PolarHBondContact O-N 3.32Å; F593-A597 PolarHBondContact O-N 2.95Å
594V97.1Very high97.1Very high0 Ų038.7 Ų38.70%021%0.206CC..Hα-helixtrans-63.8-41.8176.3-179.80000111.1L329 I393 C396 L397 M590 V591 V592 A597 L598L329-V594 HydrophobicContact CD2-CG2 3.74Å; I393-V594 HydrophobicContact CG2-CG1 3.79Å; C396-V594 HydrophobicContact CB-CG1 4.31Å; L397-V594 HydrophobicContact CD2-CB 3.84Å; L397-V594 HydrophobicContact CD2-CG1 3.4Å; L397-V594 VanDerWaalsContact CD2-CG1 3.4Å; L397-V594 HydrophobicContact CG-CG1 3.58Å; M590-V594 WeakPolarHBondContact O-CG2 3.32Å; M590-V594 PolarHBondContact O-N 3.43Å; M590-V594 VanDerWaalsContact O-N 3.09Å; V591-V594 PolarHBondContact O-N 3.39Å; V592-V594 PolarHBondContact O-N 2.89Å; V594-A597 PolarHBondContact O-N 3.27Å; V594-L598 WeakPolarHBondContact O-CB 3.35Å; V594-L598 PolarHBondContact O-N 3.38Å
595C97.7Very high97Very high57 Ų5733.8 Ų33.839%0.38519%0.186SC..Hα-helixtrans-63.8-40174-73.30000112.2V591 V592 L598 L599V591-C595 WeakPolarHBondContact O-CB 3.48Å; V591-C595 PolarHBondContact O-N 2.95Å; V591-C595 PolarHBondContact O-SG 2.65Å; V591-C595 VanDerWaalsContact O-SG 3.34Å; V592-C595 PolarHBondContact O-N 3.22Å; C595-L598 WeakPolarHBondContact O-CB 3.08Å; C595-L598 PolarHBondContact O-N 2.92Å; C595-L599 WeakPolarHBondContact O-CB 3.33Å; C595-L599 PolarHBondContact O-N 2.73Å
596G97.5Very high96.8Very high19 Ų1930.9 Ų30.920%0.19618%0.182CC..Hα-helixtrans-60.5-44.1173.700000112.3V592 F593 L599 C600V592-G596 PolarHBondContact O-N 3.17Å; F593-G596 PolarHBondContact O-N 3.32Å; G596-L599 PolarHBondContact O-N 2.79Å; G596-C600 PolarHBondContact O-N 3.31Å; G596-C600 VanDerWaalsContact O-N 3.11Å; G596-C600 PolarHBondContact O-SG 2.82Å
597A97.3Very high96.6Very high0 Ų031.9 Ų31.90%019%0.19CC..Hα-helixtrans-63.8-43.1173.700000112.1N325 M326 F593 V594 L599 C600 F601N325-A597 HydrophobicContact CB-CB 4.08Å; M326-A597 HydrophobicContact CG-CB 3.89Å; M326-A597 HydrophobicContact SD-CB 3.83Å; F593-A597 PolarHBondContact O-N 2.95Å; V594-A597 PolarHBondContact O-N 3.27Å; A597-L599 PolarHBondContact O-N 3.28Å; A597-C600 PolarHBondContact O-N 2.93Å; A597-F601 WeakPolarHBondContact O-CD2 3.38Å; A597-F601 PolarHBondContact O-N 2.87Å
598L97.3Very high96.3Very high22 Ų2232.7 Ų32.712%0.11519%0.194CC..Hα-helixtrans-58.9-48.4176.8-178.860.9000111.4T390 I393 L394 L397 V594 C595 C600 F601 L602T390-L598 HydrophobicContact CG2-CD1 4Å; I393-L598 HydrophobicContact CB-CD1 4.44Å; I393-L598 HydrophobicContact CG2-CB 3.68Å; I393-L598 HydrophobicContact CG2-CD1 4.09Å; I393-L598 HydrophobicContact CG2-CG 4.42Å; L394-L598 HydrophobicContact CD2-CD1 3.97Å; L394-L598 HydrophobicContact CD2-CD2 3.69Å; L394-L598 HydrophobicContact CG-CD1 3.85Å; L394-L598 HydrophobicContact CG-CD2 4.46Å; L397-L598 HydrophobicContact CD1-CD2 3.64Å; V594-L598 WeakPolarHBondContact O-CB 3.35Å; V594-L598 PolarHBondContact O-N 3.38Å; C595-L598 WeakPolarHBondContact O-CB 3.08Å; C595-L598 PolarHBondContact O-N 2.92Å; L598-C600 VanDerWaalsContact C-N 3.3Å; L598-C600 PolarHBondContact O-N 2.85Å; L598-F601 PolarHBondContact O-N 2.91Å; L598-L602 HydrophobicContact CD1-CD1 4.25Å; L598-L602 HydrophobicContact CD1-CG 4.21Å; L598-L602 HydrophobicContact CG-CD1 3.95Å; L598-L602 HydrophobicContact CG-CG 4.35Å; L598-L602 WeakPolarHBondContact O-CB 3.11Å; L598-L602 VanDerWaalsContact O-CG 3.32Å; L598-L602 WeakPolarHBondContact O-CG 3.44Å; L598-L602 PolarHBondContact O-N 2.76Å
599L97.9Very high96Very high101 Ų10139.8 Ų39.853%0.52922%0.215SC..Hα-helixtrans-57.4-46.1177.8179.263000110.8C595 G596 A597 F601 L602 L603C595-L599 WeakPolarHBondContact O-CB 3.33Å; C595-L599 PolarHBondContact O-N 2.73Å; G596-L599 PolarHBondContact O-N 2.79Å; A597-L599 PolarHBondContact O-N 3.28Å; L599-F601 PolarHBondContact O-N 3.4Å; L599-L602 PolarHBondContact O-N 2.83Å; L599-L603 HydrophobicContact CD1-CD1 4.28Å; L599-L603 HydrophobicContact CD1-CG 4.29Å; L599-L603 HydrophobicContact CG-CD1 4.11Å; L599-L603 WeakPolarHBondContact O-CB 3.47Å; L599-L603 VanDerWaalsContact O-CG 3.27Å; L599-L603 WeakPolarHBondContact O-CG 3.01Å; L599-L603 PolarHBondContact O-N 3.2Å
600C97.6Very high95.6Very high15 Ų1547.8 Ų47.810%0.10124%0.243CC..Hα-helixtrans-62.3-41.6178.1-67.60000112.6L318 A322 G596 A597 L598 L603 T604L318-C600 WeakPolarHBondContact O-CB 3.34Å; A322-C600 HydrophobicContact CB-CB 3.58Å; G596-C600 PolarHBondContact O-N 3.31Å; G596-C600 VanDerWaalsContact O-N 3.11Å; G596-C600 PolarHBondContact O-SG 2.82Å; A597-C600 PolarHBondContact O-N 2.93Å; L598-C600 VanDerWaalsContact C-N 3.3Å; L598-C600 PolarHBondContact O-N 2.85Å; C600-L603 PolarHBondContact O-N 2.79Å; C600-T604 WeakPolarHBondContact O-CB 3.01Å; C600-T604 PolarHBondContact O-N 2.85Å; C600-T604 PolarHBondContact O-OG1 3.31Å
601F96.8Very high95Very high1 Ų154.2 Ų54.20%0.00427%0.268CS..Hα-helixtrans-69-37.2175.9-75.2-55.5000113.1A322 C389 I393 S517 A597 L598 L599 T604 M605A322-F601 HydrophobicContact CB-CD1 4.29Å; A322-F601 HydrophobicContact CB-CD2 4.11Å; A322-F601 HydrophobicContact CB-CE1 3.98Å; A322-F601 HydrophobicContact CB-CE2 3.8Å; A322-F601 HydrophobicContact CB-CG 4.33Å; A322-F601 HydrophobicContact CB-CZ 3.71Å; C389-F601 HydrophobicContact CB-CD1 3.88Å; C389-F601 HydrophobicContact CB-CD2 4.2Å; C389-F601 HydrophobicContact CB-CE1 3.71Å; C389-F601 HydrophobicContact CB-CE2 4.04Å; C389-F601 HydrophobicContact CB-CG 4.14Å; C389-F601 HydrophobicContact CB-CZ 3.81Å; I393-F601 HydrophobicContact CG1-CD2 3.94Å; I393-F601 HydrophobicContact CG1-CE2 3.92Å; S517-F601 VanDerWaalsContact OG-CZ 3.27Å; S517-F601 WeakPolarHBondContact OG-CZ 3.15Å; A597-F601 WeakPolarHBondContact O-CD2 3.38Å; A597-F601 PolarHBondContact O-N 2.87Å; L598-F601 PolarHBondContact O-N 2.91Å; L599-F601 PolarHBondContact O-N 3.4Å; F601-T604 WeakPolarHBondContact O-CB 3.26Å; F601-T604 PolarHBondContact O-N 3.1Å; F601-M605 PolarHBondContact O-N 2.04Å
602L96.4Very high94.1Very high81 Ų8154.1 Ų54.142%0.42427%0.269SS..Hα-helixtrans-63.7-45173.6-72.8173.2000111.5T390 L598 L599 T604 M605 V606T390-L602 HydrophobicContact CG2-CD2 3.65Å; T390-L602 HydrophobicContact CG2-CG 4.25Å; L598-L602 HydrophobicContact CD1-CD1 4.25Å; L598-L602 HydrophobicContact CD1-CG 4.21Å; L598-L602 HydrophobicContact CG-CD1 3.95Å; L598-L602 HydrophobicContact CG-CG 4.35Å; L598-L602 WeakPolarHBondContact O-CB 3.11Å; L598-L602 VanDerWaalsContact O-CG 3.32Å; L598-L602 WeakPolarHBondContact O-CG 3.44Å; L598-L602 PolarHBondContact O-N 2.76Å; L599-L602 PolarHBondContact O-N 2.83Å; L602-T604 VanDerWaalsContact C-N 3.3Å; L602-T604 PolarHBondContact O-N 3.4Å; L602-M605 WeakPolarHBondContact O-CB 3.4Å; L602-M605 PolarHBondContact O-N 2.92Å; L602-V606 WeakPolarHBondContact O-CG2 3.28Å; L602-V606 PolarHBondContact O-N 2.04Å
603L96.4Very high92.7Very high78 Ų7851.2 Ų51.241%0.40826%0.257SS..Hα-helixtrans-62.8-38.4174.4-69.7175.1000111.5L318 L599 C600 M605 V606 A607L318-L603 HydrophobicContact CD1-CB 3.89Å; L318-L603 HydrophobicContact CD2-CB 3.9Å; L318-L603 HydrophobicContact CD2-CD1 3.97Å; L599-L603 HydrophobicContact CD1-CD1 4.28Å; L599-L603 HydrophobicContact CD1-CG 4.29Å; L599-L603 HydrophobicContact CG-CD1 4.11Å; L599-L603 WeakPolarHBondContact O-CB 3.47Å; L599-L603 VanDerWaalsContact O-CG 3.27Å; L599-L603 WeakPolarHBondContact O-CG 3.01Å; L599-L603 PolarHBondContact O-N 3.2Å; C600-L603 PolarHBondContact O-N 2.79Å; L603-M605 VanDerWaalsContact C-N 3.34Å; L603-M605 PolarHBondContact O-N 3.23Å; L603-V606 PolarHBondContact O-N 3.04Å; L603-A607 WeakPolarHBondContact O-CB 3.44Å; L603-A607 PolarHBondContact O-N 3.27Å
604T95.3Very high91.1Very high0 Ų053.5 Ų53.50%028%0.281CS..Hα-helixtrans-60.6-44.4174-60.10000111.2I315 L318 V319 M520 C600 F601 L602 V606 A607 L608I315-T604 HydrophobicContact CG2-CG2 4.16Å; L318-T604 VanDerWaalsContact CB-OG1 3.29Å; L318-T604 WeakPolarHBondContact CB-OG1 3.34Å; V319-T604 HydrophobicContact CG2-CG2 3.76Å; M520-T604 HydrophobicContact CE-CG2 3.74Å; C600-T604 WeakPolarHBondContact O-CB 3.01Å; C600-T604 PolarHBondContact O-N 2.85Å; C600-T604 PolarHBondContact O-OG1 3.31Å; F601-T604 WeakPolarHBondContact O-CB 3.26Å; F601-T604 PolarHBondContact O-N 3.1Å; L602-T604 VanDerWaalsContact C-N 3.3Å; L602-T604 PolarHBondContact O-N 3.4Å; T604-V606 VanDerWaalsContact C-N 3.35Å; T604-V606 PolarHBondContact O-N 3.05Å; T604-A607 PolarHBondContact O-N 2.86Å; T604-L608 HydrophobicContact CG2-CD1 3.92Å; T604-L608 HydrophobicContact CG2-CG 4.4Å; T604-L608 WeakPolarHBondContact O-CB 3.35Å; T604-L608 VanDerWaalsContact O-CG 3.3Å; T604-L608 WeakPolarHBondContact O-CG 3.42Å; T604-L608 PolarHBondContact O-N 3.38Å
605M94.3Very high89.1Confident22 Ų2262.4 Ų62.411%0.10832%0.32CS..Hα-helixtrans-59.1-44.1174.7-83-68.4-68.300112S386 K387 F601 L602 L603 L608 R609S386-M605 WeakPolarHBondContact OG-CG 3.21Å; K387-M605 HydrophobicContact CD-CE 4.3Å; K387-M605 HydrophobicContact CG-CE 3.42Å; K387-M605 VanDerWaalsContact CG-CE 3.42Å; K387-M605 HydrophobicContact CG-SD 3.7Å; F601-M605 PolarHBondContact O-N 2.04Å; L602-M605 WeakPolarHBondContact O-CB 3.4Å; L602-M605 PolarHBondContact O-N 2.92Å; L603-M605 VanDerWaalsContact C-N 3.34Å; L603-M605 PolarHBondContact O-N 3.23Å; M605-L608 PolarHBondContact O-N 3.41Å; M605-R609 WeakPolarHBondContact O-CG 2.98Å; M605-R609 PolarHBondContact O-N 2.78Å
606V94Very high86.7Confident66 Ų6667.4 Ų67.440%0.434%0.337SS..Hα-helixtrans-64-45.8176.6173.60000111L602 L603 T604 L608 R609 R610L602-V606 WeakPolarHBondContact O-CG2 3.28Å; L602-V606 PolarHBondContact O-N 2.04Å; L603-V606 PolarHBondContact O-N 3.04Å; T604-V606 VanDerWaalsContact C-N 3.35Å; T604-V606 PolarHBondContact O-N 3.05Å; V606-L608 VanDerWaalsContact C-N 3.35Å; V606-L608 PolarHBondContact O-N 2.98Å; V606-R609 PolarHBondContact O-N 3.42Å; V606-R610 WeakPolarHBondContact O-CG 3.48Å; V606-R610 PolarHBondContact O-N 3.12Å
607A93.1Very high84.1Confident21 Ų2173.5 Ų73.517%0.17437%0.365CS..Hα-helixtrans-61.2-41.917800000112.2I315 L603 T604 R610 R611I315-A607 HydrophobicContact CG1-CB 4.03Å; L603-A607 WeakPolarHBondContact O-CB 3.44Å; L603-A607 PolarHBondContact O-N 3.27Å; T604-A607 PolarHBondContact O-N 2.86Å; A607-R610 PolarHBondContact O-N 3.15Å; A607-R611 PolarHBondContact O-N 2.9Å; A607-R611 VanDerWaalsContact O-N 3.1Å
608L91.4Very high81.5Confident17 Ų1778.7 Ų78.79%0.08940%0.398CS..Hα-helixtrans-65.3-36.5176-75.1168.8000112.7I315 V382 R383 T604 M605 V606 A612I315-L608 HydrophobicContact CD1-CD2 3.66Å; I315-L608 HydrophobicContact CD1-CG 4.17Å; I315-L608 HydrophobicContact CG1-CD2 4.47Å; I315-L608 HydrophobicContact CG2-CD2 4.49Å; V382-L608 HydrophobicContact CG1-CD1 4.12Å; V382-L608 HydrophobicContact CG1-CD2 4.04Å; R383-L608 HydrophobicContact CG-CB 4.38Å; T604-L608 HydrophobicContact CG2-CD1 3.92Å; T604-L608 HydrophobicContact CG2-CG 4.4Å; T604-L608 WeakPolarHBondContact O-CB 3.35Å; T604-L608 VanDerWaalsContact O-CG 3.3Å; T604-L608 WeakPolarHBondContact O-CG 3.42Å; T604-L608 PolarHBondContact O-N 3.38Å; M605-L608 PolarHBondContact O-N 3.41Å; V606-L608 VanDerWaalsContact C-N 3.35Å; V606-L608 PolarHBondContact O-N 2.98Å; L608-A612 PolarHBondContact O-N 2.98Å
609R89.8Confident78.7Confident170 Ų17085.9 Ų85.964%0.64244%0.436SS*.Hα-helixtrans-68.5-43.4174.6-74.3179.4-173.4-1713.5111.9M605 V606 R611 A612 G613M605-R609 WeakPolarHBondContact O-CG 2.98Å; M605-R609 PolarHBondContact O-N 2.78Å; V606-R609 PolarHBondContact O-N 3.42Å; R609-R611 PolarHBondContact O-N 3.12Å; R609-A612 WeakPolarHBondContact O-CA 3.39Å; R609-A612 WeakPolarHBondContact O-CB 3.44Å; R609-A612 PolarHBondContact O-N 2.94Å; R609-A612 VanDerWaalsContact O-N 3.09Å; R609-G613 PolarHBondContact O-N 3.02Å
610R88.6Confident75.6Confident193 Ų19392.8 Ų92.873%0.72846%0.455SS*.Hα-helixtrans-61.8-42.4178.1-72.9-176.7179.7-177.10.3112.2V606 A607 A612 G613 A614V606-R610 WeakPolarHBondContact O-CG 3.48Å; V606-R610 PolarHBondContact O-N 3.12Å; A607-R610 PolarHBondContact O-N 3.15Å; R610-A612 VanDerWaalsContact C-N 3.27Å; R610-A612 PolarHBondContact O-N 3.21Å; R610-G613 PolarHBondContact O-N 2.5Å; R610-A614 WeakPolarHBondContact O-CB 3.01Å; R610-A614 PolarHBondContact O-N 2.86Å
611R84.6Confident72.6Confident140 Ų14098.2 Ų98.253%0.52849%0.488SS..Hα-helixtrans-62.7-33.1173.3-74.5-167.3179.9-170.6-2.9112.9A607 R609 F615A607-R611 PolarHBondContact O-N 2.9Å; A607-R611 VanDerWaalsContact O-N 3.1Å; R609-R611 PolarHBondContact O-N 3.12Å; R611-F615 PolarHBondContact O-N 3.44Å
612A77.6Confident69.4Low19 Ų19106 Ų10616%0.15753%0.53CS..Hα-helixtrans-65-46.5174.700000112.2R383 L608 R609 R610 F615R383-A612 VanDerWaalsContact CZ-CB 3.42Å; L608-A612 PolarHBondContact O-N 2.98Å; R609-A612 WeakPolarHBondContact O-CA 3.39Å; R609-A612 WeakPolarHBondContact O-CB 3.44Å; R609-A612 PolarHBondContact O-N 2.94Å; R609-A612 VanDerWaalsContact O-N 3.09Å; R610-A612 VanDerWaalsContact C-N 3.27Å; R610-A612 PolarHBondContact O-N 3.21Å; A612-F615 PolarHBondContact O-N 3.39Å
613G68.3Low66.2Low30 Ų30105.8 Ų105.831%0.30955%0.547SS..Hα-helixtrans-70-35.8-179.200000113.1R609 R610 F615 Q616 L617R609-G613 PolarHBondContact O-N 3.02Å; R610-G613 PolarHBondContact O-N 2.5Å; G613-F615 VanDerWaalsContact C-N 3.28Å; G613-F615 PolarHBondContact O-N 3.12Å; G613-Q616 PolarHBondContact O-N 2.92Å; G613-Q616 VanDerWaalsContact O-N 3.09Å; G613-L617 PolarHBondContact O-N 3.32Å
614A64.7Low62.8Low72 Ų72112.6 Ų112.660%0.59557%0.567SS**Hα-helixtrans-64.6-31175.300000112.9R610 Q616R610-A614 WeakPolarHBondContact O-CB 3.01Å; R610-A614 PolarHBondContact O-N 2.86Å; A614-Q616 VanDerWaalsContact C-N 3.28Å; A614-Q616 PolarHBondContact O-N 3.22Å
615F54.7Low59.5Low187 Ų187122 Ų12282%0.8260%0.604SS**THydrogen-bonded Turntrans-77.8-12175.2-151.6-95.3000112.9R611 A612 G613R611-F615 PolarHBondContact O-N 3.44Å; A612-F615 PolarHBondContact O-N 3.39Å; G613-F615 VanDerWaalsContact C-N 3.28Å; G613-F615 PolarHBondContact O-N 3.12Å
616Q46.6Very low56.2Low162 Ų162130.5 Ų130.576%0.75764%0.644SS**THydrogen-bonded Turntrans-98.9-11.1178.4-77.6179.3-3000114.1G613 A614G613-Q616 PolarHBondContact O-N 2.92Å; G613-Q616 VanDerWaalsContact O-N 3.09Å; A614-Q616 VanDerWaalsContact C-N 3.28Å; A614-Q616 PolarHBondContact O-N 3.22Å
617L43.6Very low53Low147 Ų147135.1 Ų135.177%0.7766%0.662SS**  trans-102.182165.8-87.498000108.9G613G613-L617 PolarHBondContact O-N 3.32Å
618P41.9Very low49.7Very low108 Ų108140.6 Ų140.670%0.70169%0.693SS**SBend-146.4101.799.732.2-13.2000111.6
619L39.1Very low46.5Very low173 Ų173143 Ų14391%0.90672%0.723SS**SBendtrans178.251.8159.6-99.8160.7000109.6
620R33.4Very low43.3Very low246 Ų246143.5 Ų143.593%0.92873%0.732SS**  trans-144.353.2172.7-141.3-179-175.6-169.50.4112.9
621T34.7Very low40.2Very low130 Ų130142.3 Ų142.380%0.79874%0.735SS**  trans-143.4101.1156.238.30000107.3
622N29.1Very low37.3Very low165 Ų165142 Ų14288%0.88275%0.749SS**  trans-169.6104.7134-98.8-1.5000109.7
623G29.3Very low34.7Very low76 Ų76145.4 Ų145.478%0.78478%0.777SS**  trans-91.2117.4152.900000108.9
624R24.7Very low32.8Very low220 Ų220150.4 Ų150.483%0.8380%0.804SS**  trans52.2114.4144.9-77.2-167.3169173.5-4.2122.6
625Y27Very low31Very low197 Ų197155.5 Ų155.577%0.77382%0.815SS**  trans61.2119.5135.7-60.5-70.7000122.3
626E23.4Very low29.6Very low202 Ų202156.7 Ų156.794%0.94482%0.82SS**  -152148.8124.4-114.5175.5176.900111.2
627M26.6Very low28.6Very low162 Ų162155.9 Ų155.980%0.79882%0.816SS**  trans-102.7145.6-168.2-86.7-128.5-61.600113.3
628V25.1Very low27.7Very low136 Ų136158.4 Ų158.482%0.82482%0.824SS**  trans57.8127.1139.5-175.80000120.5
629G23.5Very low27Very low68 Ų68161.9 Ų161.970%0.70183%0.829SS**  trans157.981.4152.700000117.2
630E23.5Very low26.4Very low180 Ų180158.1 Ų158.184%0.84182%0.822SS**  trans32.9122.8137.2-121169.9140.200122.6
631Q22.6Very low26.3Very low168 Ų168152.8 Ų152.879%0.78582%0.82SS**  166124.5109.1-95.2-179.6-4.900115
632T23.5Very low26Very low135 Ų135155.9 Ų155.983%0.82883%0.825SS**  trans64.2136.2143.945.10000124.2
633A24.1Very low25.9Very low90 Ų90158 Ų15874%0.74483%0.826SS**  trans-69.9177.8173.800000114.2
634P28.3Very low25.9Very low135 Ų135162.2 Ų162.288%0.87783%0.825SS**  -139.2152.592.934.4-18.8000116.6
635E25.7Very low26.1Very low178 Ų178161.2 Ų161.283%0.83283%0.83SS**  trans-66.1150.6174.2-112.7170.5139.600114.5
636K26Very low26.2Very low213 Ų213160.1 Ų160.193%0.92683%0.83SS**  trans-139.2121.3148.2-93.4-172177.9-1800110.4
637E24.9Very low26.4Very low144 Ų144155.3 Ų155.367%0.67382%0.824SS**  trans-60.3144.1177-77.9174.6106.700114.2K639E637-K639 WeakPolarHBondContact OE1-CE 3.33Å; E637-K639 IonicContact OE1-NZ 3.45Å; E637-K639 PolarHBondContact OE1-NZ 3.03Å
638Q26.4Very low26.8Very low201 Ų201153.6 Ų153.694%0.93983%0.825SS**  trans-148.1114.9139.1-119.7169.32.400110.4
639K26.3Very low26.9Very low181 Ų181155.3 Ų155.379%0.78782%0.824SS**  trans-75.2140.9-177-77.3169.6174.1157.40112.4E637E637-K639 WeakPolarHBondContact OE1-CE 3.33Å; E637-K639 IonicContact OE1-NZ 3.45Å; E637-K639 PolarHBondContact OE1-NZ 3.03Å
640A26.7Very low27.1Very low94 Ų94160.6 Ų160.678%0.77783%0.828SS**  trans-108.3143.7154.900000108.8
641P31.6Very low27.3Very low134 Ų134161.3 Ų161.387%0.8783%0.831SS**  trans-94.5125.3177.433.2-26.8000111.6
642E27.1Very low27.6Very low195 Ų195161.4 Ų161.491%0.91183%0.832SS**  trans-95.3131.1168.5-160.8171.6-166.700108.3
643K28.4Very low28.1Very low209 Ų209161.2 Ų161.291%0.90983%0.831SS**  trans-101.9113.3171.6-88.7-173.9175.7-178.20109.1
644E28.7Very low29Very low164 Ų164162.6 Ų162.677%0.76683%0.832SS**  trans-58.2143164.5-80.4176.6107.600111.8
645Q28.5Very low29.1Very low199 Ų199164.7 Ų164.793%0.9383%0.832SS**  trans-131.5100.2159.5-138167.912.200108.9
646K29.5Very low29.4Very low175 Ų175165.6 Ų165.676%0.76183%0.833SS**  trans-86.2139.3165.8-83.9175.5177.7164.10109.3
647A27.8Very low29.9Very low100 Ų100165.6 Ų165.683%0.82685%0.851SS**  trans-82.7149.5160.700000110.6
648P34.6Very low30.1Very low126 Ų126166.7 Ų166.782%0.81886%0.86SS**  trans-123.4153.2149.134.3-21.5000112.3
649E26.9Very low30.3Very low172 Ų172164.8 Ų164.880%0.80486%0.856SS**  trans-95154.7175.4-162.2-171.1154.400110.8
650K27.8Very low30.6Very low180 Ų180163.9 Ų163.978%0.78386%0.86SS**  trans87112.6166.7-58.1-171177.1-178.40118.9
651E27.4Very low30.8Very low195 Ų195168.1 Ų168.191%0.91187%0.865SS**  169.2152.989.2-161.9159.317800111.4
652Q30.1Very low30.8Very low170 Ų170170.2 Ų170.279%0.79486%0.864SS**  trans-84.1153.8-158.9-73.4165.3-46.100117.1
653T33.2Very low31Very low131 Ų131168.5 Ų168.580%0.80486%0.861SS**  trans68.7154.3146.440.40000119.8
654P43.9Very low31.2Very low118 Ų118165.6 Ų165.677%0.76686%0.858SS**  cis-136.6153.925.238-18000119.2
655M30.3Very low31.4Very low180 Ų180165.8 Ų165.889%0.88787%0.865SS**  34.3143.8127.7-137.2177.6-161.400123.7
656K31.7Very low31.6Very low197 Ų197163 Ų16386%0.85786%0.859SS**  trans102.7123.8167.8-63.1177.4178.6179.80112.4
657T36Very low31.8Very low212 Ų212161.9 Ų161.9100%1.30187%0.868SS**  cis-147.9021.2-47.20000109.5

Retrieved 657 of 657 residues in 834 ms (Link to these results)