A0A087X760_POEFO Loading...

Sema domain-containing protein

AlphaFold DB , UniProt , Accession A0A087X760, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 861 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.4Very low35.4Very low254 Ų254136.4 Ų136.4100%1.25176%0.755SS**  0122.90-65.1151.488.500107.3
2G38.7Very low35.1Very low82 Ų82136.9 Ų136.985%0.84575%0.754SS**  trans177.813.6-173.100000119.3
3G32.9Very low34.8Very low55 Ų55134.3 Ų134.357%0.56774%0.744SS**SBendtrans-107.8-23.3-178.500000115.8
4T36.9Very low34.4Very low132 Ų132129.2 Ų129.281%0.8174%0.737SS**THydrogen-bonded Turntrans-92.7-3-161.634.50000116.3
5R37.4Very low34.3Very low224 Ų224135.3 Ų135.385%0.84574%0.744SS**THydrogen-bonded Turntrans-91.9-16.7179.3-80.3-171.6171-175.9-3.1115.3
6V41.5Very low33.8Very low106 Ų106136.8 Ų136.864%0.64274%0.744SS**Hα-helixtrans-83.3-41.4-176.3-177.20000112.2L8 L9 M10V6-L8 VanDerWaalsContact C-N 3.27Å; V6-L8 PolarHBondContact O-N 2.72Å; V6-L9 PolarHBondContact O-N 3.3Å; V6-M10 PolarHBondContact O-N 3.32Å
7L36Very low33.8Very low126 Ų126143.1 Ų143.166%0.6675%0.754SS**Hα-helixtrans-62.1-33.8177.4-94.774.8000112.8L9 M10 L11L7-L9 VanDerWaalsContact C-N 3.34Å; L7-L9 PolarHBondContact O-N 3.08Å; L7-M10 PolarHBondContact O-N 3.21Å; L7-L11 PolarHBondContact O-N 3.31Å; L7-L11 VanDerWaalsContact O-N 3.14Å
8L32.9Very low33.9Very low115 Ų115140.4 Ų140.460%0.60275%0.749SS**Hα-helixtrans-72.1-26.1-176.6-147.377.1000113.1V6 L12V6-L8 VanDerWaalsContact C-N 3.27Å; V6-L8 PolarHBondContact O-N 2.72Å; L8-L12 WeakPolarHBondContact O-CG 3.18Å
9L31.8Very low34.3Very low123 Ų123136.4 Ų136.464%0.64474%0.738SS**Hα-helixtrans-76.1-39.7171-99.274.2000111.7V6 L7 L11 L12 V13V6-L9 PolarHBondContact O-N 3.3Å; L7-L9 VanDerWaalsContact C-N 3.34Å; L7-L9 PolarHBondContact O-N 3.08Å; L9-L11 PolarHBondContact O-N 3.16Å; L9-L12 PolarHBondContact O-N 2.98Å; L9-V13 PolarHBondContact O-N 2.9Å; L9-V13 VanDerWaalsContact O-N 3.07Å
10M32Very low35.1Very low150 Ų150134 Ų13474%0.73974%0.738SS**Hα-helixtrans-61.8-29.9175.8-77.6-64.9-160.100112.8V6 L7 L12V6-M10 PolarHBondContact O-N 3.32Å; L7-M10 PolarHBondContact O-N 3.21Å; M10-L12 VanDerWaalsContact C-N 3.32Å
11L30.8Very low36.3Very low133 Ų133129.4 Ų129.470%0.69671%0.712SS**THydrogen-bonded Turntrans-78.7-8.6173.7-76.4164.3000114.5L7 L9L7-L11 PolarHBondContact O-N 3.31Å; L7-L11 VanDerWaalsContact O-N 3.14Å; L9-L11 PolarHBondContact O-N 3.16Å
12L31.4Very low37.7Very low143 Ų143122.1 Ų122.175%0.74968%0.678SS**THydrogen-bonded Turntrans-112-9178.4-70.7172.9000113.9L8 L9 M10 G14L8-L12 WeakPolarHBondContact O-CG 3.18Å; L9-L12 PolarHBondContact O-N 2.98Å; M10-L12 VanDerWaalsContact C-N 3.32Å; L12-G14 VanDerWaalsContact C-N 3.27Å
13V31.9Very low39.3Very low103 Ų103120.8 Ų120.862%0.62465%0.647SS**  trans-9823.6163.1-160.30000110.9L9 W15L9-V13 PolarHBondContact O-N 2.9Å; L9-V13 VanDerWaalsContact O-N 3.07Å; V13-W15 PolarHBondContact O-N 3.45Å
14G28.7Very low41.6Very low63 Ų63121 Ų12165%0.64964%0.636SS**  trans-67.258.7152.900000110.5L12 E16L12-G14 VanDerWaalsContact C-N 3.27Å; G14-E16 PolarHBondContact O-N 3.19Å
15W32.7Very low44.1Very low220 Ų220115.2 Ų115.283%0.83360%0.6SS**  trans-68.6100.7176.4-140.6-21.4000106.6V13 R17V13-W15 PolarHBondContact O-N 3.45Å; W15-R17 VanDerWaalsContact C-N 3.34Å; W15-R17 PolarHBondContact O-N 3.3Å
16E27.3Very low46.7Very low160 Ų160107.9 Ų107.975%0.74858%0.58SS**  trans-52.6109.4156.8-73.3-168141.500106.2G14 S18G14-E16 PolarHBondContact O-N 3.19Å; E16-S18 PolarHBondContact O-N 3.38Å
17R32.9Very low49.2Very low243 Ų243103.5 Ų103.592%0.91755%0.554SS**  trans-67.177156.6-79-174.6171.1-169.2-2.1106W15 A19W15-R17 VanDerWaalsContact C-N 3.34Å; W15-R17 PolarHBondContact O-N 3.3Å; R17-A19 PolarHBondContact O-N 3.36Å
18S35.3Very low52Low95 Ų9597.5 Ų97.566%0.66452%0.522SS*.  trans-52.894.8160.4-65.90000105.8E16 A20E16-S18 PolarHBondContact O-N 3.38Å; S18-A20 PolarHBondContact O-N 2.94Å
19A41.7Very low55Low64 Ų6493.6 Ų93.653%0.52950%0.501SS..  trans-56.4109.2-169.400000106.9R17 L21R17-A19 PolarHBondContact O-N 3.36Å; A19-L21 PolarHBondContact O-N 3.44Å
20A50.7Low58Low89 Ų8990.2 Ų90.274%0.73649%0.485SS*.  trans-62.7108-172.800000106.6S18 N22S18-A20 PolarHBondContact O-N 2.94Å; A20-N22 PolarHBondContact O-N 2.97Å
21L60.9Low61Low38 Ų3883.7 Ų83.720%0.19945%0.453CS..PPolyproline II helixtrans-46.8122.8-177.2178.969.4000107.5A19 W23 L288 P409 L410 L412A19-L21 PolarHBondContact O-N 3.44Å; L21-W23 PolarHBondContact O-N 3.32Å; L21-L288 HydrophobicContact CD2-CD1 3.87Å; L21-L288 HydrophobicContact CD2-CD2 4.11Å; L21-P409 WeakPolarHBondContact CD1-O 3.24Å; L21-P409 HydrophobicContact CD2-CB 4.11Å; L21-L410 WeakPolarHBondContact CD1-O 3.1Å; L21-L412 HydrophobicContact CD2-CB 4.24Å
22N67.1Low64Low100 Ų10085.3 Ų85.354%0.53545%0.45SS..PPolyproline II helixtrans-69.8118.9-177.7-167.41000108A20 P25A20-N22 PolarHBondContact O-N 2.97Å; N22-P25 HydrophobicContact CB-CB 4.36Å
23W72.5Confident66.9Low54 Ų5480.7 Ų80.721%0.20542%0.423CS..SBendtrans-89117.4-175.4-87.733.6000109.4L21 L288 R291 W322 L412L21-W23 PolarHBondContact O-N 3.32Å; W23-L288 HydrophobicContact CZ2-CD1 3.79Å; W23-R291 HydrophobicContact CZ2-CG 4.48Å; W23-W322 HydrophobicContact CH2-CE3 4.16Å; W23-W322 AromaticContact CH2-CH2 3.59Å; W23-W322 HydrophobicContact CH2-CH2 3.59Å; W23-W322 HydrophobicContact CH2-CZ2 4.48Å; W23-W322 AromaticContact CH2-CZ3 3.37Å; W23-W322 HydrophobicContact CH2-CZ3 3.37Å; W23-W322 HydrophobicContact CZ2-CZ3 4.47Å; W23-W322 HydrophobicContact CZ3-CE3 4.35Å; W23-W322 AromaticContact CZ3-CH2 3.99Å; W23-W322 HydrophobicContact CZ3-CH2 3.99Å; W23-W322 HydrophobicContact CZ3-CZ2 4.47Å; W23-W322 AromaticContact CZ3-CZ3 3.9Å; W23-W322 HydrophobicContact CZ3-CZ3 3.9Å; W23-L412 HydrophobicContact CD2-CD2 3.61Å; W23-L412 HydrophobicContact CE3-CD2 4.21Å; W23-L412 HydrophobicContact CG-CD2 3.93Å; W23-L412 HydrophobicContact CH2-CD2 4.24Å; W23-L412 HydrophobicContact CZ2-CD2 3.61Å
24N82.1Confident69.7Low61 Ų6182.7 Ų82.733%0.32643%0.426SS..SBendtrans59.861.6-173.4-160.586.7000112.3V26 L412 T413 K414N24-V26 PolarHBondContact O-N 2.79Å; N24-L412 VanDerWaalsContact CA-O 3.29Å; N24-L412 WeakPolarHBondContact CA-O 3.21Å; N24-L412 PolarHBondContact N-O 3.44Å; N24-T413 WeakPolarHBondContact OD1-CG2 3.32Å; N24-K414 PolarHBondContact OD1-N 3.04Å; N24-K414 PolarHBondContact OD1-O 2.69Å
25P88.2Confident72.4Confident10 Ų1085.1 Ų85.17%0.06542%0.424CS..PPolyproline II helixtrans-62.7128-178.127.7-33.1000110.4N22 L411 L412 V458N22-P25 HydrophobicContact CB-CB 4.36Å; P25-L411 HydrophobicContact CG-CD1 3.41Å; P25-L411 VanDerWaalsContact CG-CD1 3.41Å; P25-L412 WeakPolarHBondContact CD-O 3.43Å; P25-V458 HydrophobicContact CB-CG2 4.35Å; P25-V458 HydrophobicContact CG-CG2 3.97Å
26V91.3Very high74.8Confident70 Ų7074.6 Ų74.642%0.42438%0.384SS..PPolyproline II helixtrans-71.8128.4-178.2178.40000109.8N24 R28 N588 L589N24-V26 PolarHBondContact O-N 2.79Å; V26-R28 PolarHBondContact O-N 2.93Å; V26-N588 HydrophobicContact CG1-CB 3.66Å; V26-L589 HydrophobicContact CB-CD2 3.91Å; V26-L589 HydrophobicContact CG1-CD2 4.36Å
27P95.3Very high77.5Confident13 Ų1370.3 Ų70.38%0.08436%0.364CS..PPolyproline II helixtrans-58.8126.2173.1-2434.8000111.4K29 V458 E461 N588P27-K29 VanDerWaalsContact C-N 3.31Å; P27-K29 PolarHBondContact O-N 3.07Å; P27-V458 HydrophobicContact CB-CB 4.44Å; P27-V458 HydrophobicContact CB-CG1 3.71Å; P27-V458 HydrophobicContact CG-CG1 3.84Å; P27-E461 HydrophobicContact CB-CB 4.03Å; P27-E461 HydrophobicContact CB-CG 3.94Å; P27-E461 HydrophobicContact CG-CB 4.07Å; P27-E461 HydrophobicContact CG-CG 4.05Å; P27-N588 WeakPolarHBondContact O-CB 3.34Å; P27-N588 PolarHBondContact O-ND2 3.38Å
28R95.6Very high79.8Confident1 Ų166.1 Ų66.10%0.00436%0.36CS..SBendtrans-58.4-41.9-174.4-173.1-169.4170.9-107.9-10112V26 V458 I459 D507 L510 A511 S587 N588 L589 E639V26-R28 PolarHBondContact O-N 2.93Å; R28-V458 PolarHBondContact N-O 3.11Å; R28-I459 WeakPolarHBondContact CB-O 3.42Å; R28-D507 IonicContact CZ-OD1 2.68Å; R28-D507 VanDerWaalsContact CZ-OD1 3.27Å; R28-D507 PolarHBondContact NH1-O 3.44Å; R28-D507 IonicContact NH1-OD1 2.89Å; R28-D507 PolarHBondContact NH1-OD1 2.83Å; R28-D507 IonicContact NH2-OD1 2.84Å; R28-D507 PolarHBondContact NH2-OD1 2.93Å; R28-L510 VanDerWaalsContact CD-O 3.27Å; R28-L510 WeakPolarHBondContact CD-O 3.45Å; R28-L510 PolarHBondContact NE-O 3.18Å; R28-A511 VanDerWaalsContact NH1-CA 3.35Å; R28-S587 WeakPolarHBondContact CG-OG 3.29Å; R28-S587 CarbonylContact O-C 3.59Å; R28-S587 VanDerWaalsContact O-CA 3.31Å; R28-S587 WeakPolarHBondContact O-CA 3.49Å; R28-S587 PolarHBondContact O-OG 3.18Å; R28-N588 PolarHBondContact O-N 2.81Å; R28-L589 HydrophobicContact CB-CD1 3.98Å; R28-L589 HydrophobicContact CB-CG 4.38Å; R28-L589 HydrophobicContact CG-CD1 4.03Å; R28-L589 HydrophobicContact CG-CG 4.37Å; R28-E639 IonicContact CZ-OE1 3.63Å; R28-E639 IonicContact CZ-OE2 3.56Å; R28-E639 IonicContact NE-OE1 2.98Å; R28-E639 PolarHBondContact NE-OE1 3.43Å; R28-E639 IonicContact NE-OE2 2.71Å; R28-E639 PolarHBondContact NE-OE2 3.02Å; R28-E639 IonicContact NH2-OE1 3.94Å; R28-E639 IonicContact NH2-OE2 3.88Å; R28-E639 PolarHBondContact NH2-OE2 3.08Å
29K94.8Very high82.1Confident33 Ų3363.2 Ų63.214%0.14334%0.339CS..EExtended strand (participates in β ladder)trans-123.4148167.5-60-163.8-176.6-167.90111.6P27 I459 E460 E461 R501 Y502 D507 V586P27-K29 VanDerWaalsContact C-N 3.31Å; P27-K29 PolarHBondContact O-N 3.07Å; K29-I459 PolarHBondContact N-O 2.78Å; K29-E460 HydrophobicContact CB-CB 4.31Å; K29-E460 CarbonylContact O-C 3.59Å; K29-E460 WeakPolarHBondContact O-CA 3.36Å; K29-E460 WeakPolarHBondContact O-CB 3.43Å; K29-E461 PolarHBondContact O-N 3.43Å; K29-R501 PolarHBondContact NZ-O 3.27Å; K29-Y502 HydrophobicContact CD-CE1 4.12Å; K29-D507 VanDerWaalsContact CE-OD1 3.31Å; K29-D507 WeakPolarHBondContact CE-OD1 3.24Å; K29-D507 IonicContact NZ-OD1 2.68Å; K29-D507 PolarHBondContact NZ-OD1 2.81Å; K29-D507 IonicContact NZ-OD2 2.8Å; K29-D507 PolarHBondContact NZ-OD2 2.84Å; K29-V586 VanDerWaalsContact CE-O 3.29Å; K29-V586 WeakPolarHBondContact CE-O 3.45Å
30T95.2Very high84.4Confident52 Ų5260.8 Ų60.832%0.31932%0.317SS..EExtended strand (participates in β ladder)trans-114119.4171.4-57.10000107.8W445 E461 N588T30-W445 HydrophobicContact CG2-CH2 4.24Å; T30-W445 HydrophobicContact CG2-CZ3 3.88Å; T30-E461 WeakPolarHBondContact CB-OE1 3.46Å; T30-E461 HydrophobicContact CG2-CG 3.87Å; T30-E461 VanDerWaalsContact CG2-OE1 3.29Å; T30-E461 WeakPolarHBondContact CG2-OE1 3.38Å; T30-E461 PolarHBondContact OG1-OE1 2.79Å; T30-N588 PolarHBondContact OG1-ND2 2.84Å
31V95.1Very high86.5Confident12 Ų1258.3 Ų58.37%0.07330%0.297CS..EExtended strand (participates in β ladder)trans-105.5115.2178.8-179.60000108.4D35 E461 I462 Q463V31-D35 HydrophobicContact CG1-CB 4.13Å; V31-E461 PolarHBondContact N-O 2.86Å; V31-I462 HydrophobicContact CB-CG1 4.34Å; V31-I462 HydrophobicContact CB-CG2 4.39Å; V31-I462 HydrophobicContact CG1-CG2 4.38Å; V31-Q463 PolarHBondContact O-N 3.27Å
32R94.4Very high88.1Confident168 Ų16859.3 Ų59.363%0.63430%0.298SS*.  trans-79.5165.8178.7-59.7177.9166.8-170.7-5.4110.4Q34 D35 G36R32-Q34 VanDerWaalsContact C-N 3.29Å; R32-Q34 PolarHBondContact O-N 2.75Å; R32-D35 WeakPolarHBondContact CB-OD2 3.44Å; R32-D35 PolarHBondContact N-OD2 2.96Å; R32-D35 PolarHBondContact O-N 3.27Å; R32-D35 VanDerWaalsContact O-N 3.15Å; R32-G36 PolarHBondContact O-N 3.01Å
33Y92.3Very high89.6Confident45 Ų4555.3 Ų55.318%0.17628%0.276CS..Hα-helixtrans-53.6-46.1-177.9177.2-94000112.4D35 G36 Q37 R42 F465 D466Y33-D35 PolarHBondContact O-N 2.66Å; Y33-G36 PolarHBondContact O-N 2.87Å; Y33-Q37 HydrophobicContact CE1-CB 4.37Å; Y33-Q37 WeakPolarHBondContact O-CB 3.38Å; Y33-Q37 PolarHBondContact O-N 2.84Å; Y33-R42 VanDerWaalsContact CE2-NH2 3.27Å; Y33-F465 VanDerWaalsContact CD2-C 3.41Å; Y33-D466 HydrophobicContact CD1-CB 3.89Å; Y33-D466 HydrophobicContact CD2-CB 4.11Å; Y33-D466 HydrophobicContact CE1-CB 3.87Å; Y33-D466 HydrophobicContact CE2-CB 4.03Å; Y33-D466 HydrophobicContact CG-CB 4.03Å
34Q90.1Very high90.7Very high145 Ų14556.3 Ų56.368%0.67829%0.291SS*.Hα-helixtrans-62.8-37.8-179.4-65.3174.4-600113.1R32R32-Q34 VanDerWaalsContact C-N 3.29Å; R32-Q34 PolarHBondContact O-N 2.75Å
35D85.5Confident91.4Very high114 Ų11455.3 Ų55.361%0.6129%0.287SS*.Hα-helixtrans-79.7-22.1178.1-44.6-58.7000112.5V31 R32 Y33V31-D35 HydrophobicContact CG1-CB 4.13Å; R32-D35 WeakPolarHBondContact CB-OD2 3.44Å; R32-D35 PolarHBondContact N-OD2 2.96Å; R32-D35 PolarHBondContact O-N 3.27Å; R32-D35 VanDerWaalsContact O-N 3.15Å; Y33-D35 PolarHBondContact O-N 2.66Å
36G82.5Confident91.8Very high0 Ų064.3 Ų64.30%033%0.328CS..Hα-helixtrans-96-32.3-174.100000114.6R32 Y33 D38 S39R32-G36 PolarHBondContact O-N 3.01Å; Y33-G36 PolarHBondContact O-N 2.87Å; G36-D38 PolarHBondContact O-N 3.19Å; G36-S39 PolarHBondContact O-N 3.41Å; G36-S39 PolarHBondContact O-OG 3.16Å
37Q83.1Confident91.9Very high69 Ų6963.4 Ų63.432%0.32233%0.333SS..G310 helixtrans-53.9-44.4-164.561.4-177.12.800114.2Y33 S39 M40Y33-Q37 HydrophobicContact CE1-CB 4.37Å; Y33-Q37 WeakPolarHBondContact O-CB 3.38Å; Y33-Q37 PolarHBondContact O-N 2.84Å; Q37-S39 PolarHBondContact O-N 3.36Å; Q37-S39 VanDerWaalsContact O-N 3.11Å; Q37-M40 PolarHBondContact O-N 3.18Å
38D81.7Confident92Very high155 Ų15563.6 Ų63.683%0.82933%0.334SS*.G310 helixtrans-69.2-11.9-177.1-58.2-25.6000113.1G36G36-D38 PolarHBondContact O-N 3.19Å
39S83.3Confident92.1Very high34 Ų3467.4 Ų67.424%0.23835%0.351CS..G310 helixtrans-97.710.3175.266.70000114.1G36 Q37 P495 N498 R501G36-S39 PolarHBondContact O-N 3.41Å; G36-S39 PolarHBondContact O-OG 3.16Å; Q37-S39 PolarHBondContact O-N 3.36Å; Q37-S39 VanDerWaalsContact O-N 3.11Å; S39-P495 WeakPolarHBondContact O-CD 3.46Å; S39-N498 WeakPolarHBondContact CB-ND2 3.35Å; S39-R501 PolarHBondContact OG-NH2 3.25Å; S39-R501 VanDerWaalsContact OG-NH2 3.17Å
40M90.8Very high92.2Very high13 Ų1367.1 Ų67.16%0.06435%0.351CS..  trans-133116.8-176.1-52-166.6-86.400111.1Q37 I462 L464 L494Q37-M40 PolarHBondContact O-N 3.18Å; M40-I462 HydrophobicContact SD-CG2 4.43Å; M40-L464 HydrophobicContact SD-CD2 4.14Å; M40-L494 HydrophobicContact CB-CD1 4.26Å; M40-L494 HydrophobicContact CB-CG 4.45Å; M40-L494 HydrophobicContact CG-CD1 4.05Å; M40-L494 HydrophobicContact CG-CD2 4.41Å; M40-L494 HydrophobicContact CG-CG 3.83Å; M40-L494 HydrophobicContact SD-CD1 3.75Å; M40-L494 HydrophobicContact SD-CD2 3.79Å; M40-L494 HydrophobicContact SD-CG 3.75Å
41A94.3Very high92.4Very high37 Ų3764.7 Ų64.731%0.30634%0.336SS..EExtended strand (participates in β ladder)trans-75.7150.4170.200000110.2I79 L492 Q493A41-I79 HydrophobicContact CB-CG1 4.28Å; A41-L492 CarbonylContact O-C 3.58Å; A41-L492 WeakPolarHBondContact O-CA 3.41Å; A41-Q493 HydrophobicContact CB-CB 4.22Å; A41-Q493 PolarHBondContact N-O 2.82Å; A41-Q493 VanDerWaalsContact N-O 3.1Å; A41-Q493 PolarHBondContact O-N 2.88Å
42R95.4Very high92.4Very high59 Ų5965.4 Ų65.422%0.22334%0.341CS..EExtended strand (participates in β ladder)trans-134.2145.6-170.3-58.1-174.2173.5-96.2-9.4111.2Y33 L464 E490 V491 L492Y33-R42 VanDerWaalsContact CE2-NH2 3.27Å; R42-L464 PolarHBondContact NH1-O 2.94Å; R42-L464 PolarHBondContact NH2-O 3.3Å; R42-E490 WeakPolarHBondContact CD-OE2 3.46Å; R42-E490 IonicContact CZ-OE2 2.69Å; R42-E490 IonicContact NE-OE2 2.69Å; R42-E490 VanDerWaalsContact NH1-CD 3.34Å; R42-E490 IonicContact NH1-OE1 2.73Å; R42-E490 IonicContact NH1-OE2 2.71Å; R42-E490 PolarHBondContact NH1-OE2 2.84Å; R42-V491 CarbonylContact C-O 3.57Å; R42-V491 WeakPolarHBondContact CA-O 3.17Å; R42-L492 HydrophobicContact CB-CD2 4.46Å; R42-L492 HydrophobicContact CG-CD2 3.79Å; R42-L492 VanDerWaalsContact NH1-CD2 3.28Å
43F97.7Very high92.5Very high17 Ų1759.6 Ų59.68%0.07532%0.322CS..EExtended strand (participates in β ladder)trans-137.4127171.9177.2-91.4000110.8V45 Y51 F72 L74 I79 E490 V491F43-V45 HydrophobicContact CE1-CG2 4.07Å; F43-V45 HydrophobicContact CE2-CG2 4.34Å; F43-V45 HydrophobicContact CZ-CG2 3.63Å; F43-Y51 HydrophobicContact CD1-CE1 4.48Å; F43-Y51 HydrophobicContact CE1-CE1 4.31Å; F43-F72 HydrophobicContact CE1-CB 4.43Å; F43-F72 AromaticContact CE1-CD1 3.94Å; F43-F72 HydrophobicContact CE1-CD1 3.94Å; F43-F72 AromaticContact CE1-CD2 4Å; F43-F72 HydrophobicContact CE1-CD2 4Å; F43-F72 HydrophobicContact CE1-CE1 4.14Å; F43-F72 HydrophobicContact CE1-CE2 4.19Å; F43-F72 AromaticContact CE1-CG 3.85Å; F43-F72 HydrophobicContact CE1-CG 3.85Å; F43-F72 HydrophobicContact CE1-CZ 4.25Å; F43-F72 HydrophobicContact CZ-CB 4.5Å; F43-F72 AromaticContact CZ-CD1 3.66Å; F43-F72 HydrophobicContact CZ-CD1 3.66Å; F43-F72 AromaticContact CZ-CE1 3.93Å; F43-F72 HydrophobicContact CZ-CE1 3.93Å; F43-F72 AromaticContact CZ-CG 3.99Å; F43-F72 HydrophobicContact CZ-CG 3.99Å; F43-F72 HydrophobicContact CZ-CZ 4.47Å; F43-L74 HydrophobicContact CB-CD1 4.12Å; F43-L74 HydrophobicContact CD1-CD1 3.7Å; F43-L74 HydrophobicContact CD1-CD2 4.3Å; F43-L74 HydrophobicContact CD2-CD1 4.15Å; F43-L74 HydrophobicContact CD2-CD2 3.82Å; F43-L74 HydrophobicContact CE1-CD1 4.15Å; F43-L74 HydrophobicContact CE1-CD2 4.07Å; F43-L74 HydrophobicContact CE2-CD2 3.57Å; F43-L74 HydrophobicContact CG-CD1 3.7Å; F43-L74 HydrophobicContact CG-CD2 4.19Å; F43-L74 HydrophobicContact CZ-CD2 3.71Å; F43-I79 HydrophobicContact CB-CB 4.45Å; F43-I79 HydrophobicContact CB-CD1 4.05Å; F43-I79 HydrophobicContact CB-CG1 4.25Å; F43-I79 WeakPolarHBondContact CD2-O 3.06Å; F43-E490 CarbonylContact O-C 3.52Å; F43-E490 WeakPolarHBondContact O-CA 3.16Å; F43-E490 WeakPolarHBondContact O-CB 3.24Å; F43-V491 HydrophobicContact CB-CB 4.45Å; F43-V491 PolarHBondContact N-O 2.03Å; F43-V491 PolarHBondContact O-N 3.38Å
44S96.8Very high92.7Very high74 Ų7458 Ų5852%0.51732%0.316SS..  trans-154.4153.5170.7590000110.5S489S44-S489 WeakPolarHBondContact CB-O 3.25Å
45V97.2Very high93Very high40 Ų4051.9 Ų51.924%0.24229%0.289CS..  trans-123.9134177.9177.70000109.4F43 G47 V48 Y51 F72F43-V45 HydrophobicContact CE1-CG2 4.07Å; F43-V45 HydrophobicContact CE2-CG2 4.34Å; F43-V45 HydrophobicContact CZ-CG2 3.63Å; V45-G47 PolarHBondContact O-N 2.84Å; V45-V48 HydrophobicContact CB-CB 4.28Å; V45-V48 HydrophobicContact CB-CG2 4.19Å; V45-V48 HydrophobicContact CG1-CG2 4.09Å; V45-V48 PolarHBondContact O-N 2.91Å; V45-Y51 PolarHBondContact N-OH 3.35Å; V45-Y51 PolarHBondContact O-OH 2.98Å; V45-F72 HydrophobicContact CB-CE1 4.35Å; V45-F72 HydrophobicContact CB-CZ 4.16Å; V45-F72 HydrophobicContact CG2-CE1 3.69Å; V45-F72 HydrophobicContact CG2-CZ 3.9Å
46Q95.6Very high93.5Very high200 Ų20048.1 Ų48.194%0.93527%0.269SS*.THydrogen-bonded Turntrans-59.6123.4-175.6-172.4178.4600111.3V48Q46-V48 VanDerWaalsContact C-N 3.34Å
47G94.4Very high93.9Very high51 Ų5149.1 Ų49.153%0.52628%0.276SS..THydrogen-bonded Turntrans88.8-10.7-178.800000115.2V45 F49V45-G47 PolarHBondContact O-N 2.84Å; G47-F49 WeakPolarHBondContact O-CD2 3.42Å; G47-F49 VanDerWaalsContact O-CE2 3.26Å; G47-F49 WeakPolarHBondContact O-CE2 3.32Å
48V96.8Very high93.7Very high16 Ų1650.5 Ų50.510%0.09729%0.285CS..  trans-96.7137175-175.90000109.9V45 Q46 Y51 A67 F72V45-V48 HydrophobicContact CB-CB 4.28Å; V45-V48 HydrophobicContact CB-CG2 4.19Å; V45-V48 HydrophobicContact CG1-CG2 4.09Å; V45-V48 PolarHBondContact O-N 2.91Å; Q46-V48 VanDerWaalsContact C-N 3.34Å; V48-Y51 HydrophobicContact CG1-CE1 4.1Å; V48-Y51 WeakPolarHBondContact O-CE2 3.49Å; V48-Y51 PolarHBondContact O-OH 2.84Å; V48-A67 HydrophobicContact CG1-CB 3.62Å; V48-F72 HydrophobicContact CB-CZ 4.39Å; V48-F72 HydrophobicContact CG1-CE2 3.96Å; V48-F72 HydrophobicContact CG1-CZ 3.94Å; V48-F72 HydrophobicContact CG2-CZ 4.33Å
49F97Very high93.7Very high82 Ų8250.9 Ų50.936%0.3628%0.282SS..  trans-140.3168.7-172.3-60.8-84.6000111.3G47 R68 R488G47-F49 WeakPolarHBondContact O-CD2 3.42Å; G47-F49 VanDerWaalsContact O-CE2 3.26Å; G47-F49 WeakPolarHBondContact O-CE2 3.32Å; F49-R68 WeakPolarHBondContact O-CB 3.45Å; F49-R68 PolarHBondContact O-N 2.92Å; F49-R488 CarbonylContact C-O 3.57Å; F49-R488 VanDerWaalsContact CA-O 3.3Å; F49-R488 WeakPolarHBondContact CA-O 3.28Å; F49-R488 WeakPolarHBondContact CB-O 2.99Å
50N97.6Very high93.9Very high27 Ų2750.7 Ų50.714%0.14428%0.277CS..  trans57.562.4173.2-62.4108000113.5S52 A67 R68 Y113 R488N50-S52 PolarHBondContact O-N 3.01Å; N50-S52 PolarHBondContact O-OG 2.81Å; N50-A67 WeakPolarHBondContact O-CA 3.05Å; N50-R68 HydrophobicContact CB-CB 4.42Å; N50-Y113 HydrophobicContact CB-CD1 4.23Å; N50-Y113 HydrophobicContact CB-CE1 3.78Å; N50-R488 PolarHBondContact N-O 2.84Å
51Y98Very high93.9Very high0 Ų058.8 Ų58.80%031%0.307CS..  trans-72.661.3176.4-55.5-98.7000110.2F43 V45 V48 V65 A67 F72 S473 G486 S487 S489 V491F43-Y51 HydrophobicContact CD1-CE1 4.48Å; F43-Y51 HydrophobicContact CE1-CE1 4.31Å; V45-Y51 PolarHBondContact N-OH 3.35Å; V45-Y51 PolarHBondContact O-OH 2.98Å; V48-Y51 HydrophobicContact CG1-CE1 4.1Å; V48-Y51 WeakPolarHBondContact O-CE2 3.49Å; V48-Y51 PolarHBondContact O-OH 2.84Å; Y51-V65 HydrophobicContact CD1-CG1 3.96Å; Y51-A67 HydrophobicContact CD1-CB 3.98Å; Y51-A67 HydrophobicContact CE1-CB 4.29Å; Y51-A67 HydrophobicContact CG-CB 4.39Å; Y51-F72 HydrophobicContact CD1-CE2 4.24Å; Y51-F72 HydrophobicContact CE1-CD2 4.42Å; Y51-F72 AromaticContact CE1-CE2 3.73Å; Y51-F72 HydrophobicContact CE1-CE2 3.73Å; Y51-F72 HydrophobicContact CE1-CZ 4.37Å; Y51-S473 PolarHBondContact O-OG 3.29Å; Y51-S473 VanDerWaalsContact O-OG 3.13Å; Y51-G486 WeakPolarHBondContact O-CA 3.44Å; Y51-S487 PolarHBondContact N-O 3.36Å; Y51-S489 VanDerWaalsContact CE2-C 3.44Å; Y51-S489 WeakPolarHBondContact CE2-O 3.44Å; Y51-V491 HydrophobicContact CD1-CG2 3.89Å; Y51-V491 HydrophobicContact CG-CG2 3.95Å
52S95.1Very high94Very high28 Ų2858.1 Ų58.120%0.19630%0.299CS..  trans-96.8-7.8-161.755.80000114.3N50 G66 S473N50-S52 PolarHBondContact O-N 3.01Å; N50-S52 PolarHBondContact O-OG 2.81Å; S52-G66 PolarHBondContact N-O 3.41Å; S52-S473 WeakPolarHBondContact O-CB 3.43Å
53M96.8Very high94.1Very high45 Ų4555.3 Ų55.322%0.22229%0.289CS..EExtended strand (participates in β ladder)trans-117.5122.6170.1-170.367.1-166.300109.9T55 V65 G66 I114 L117M53-T55 WeakPolarHBondContact CE-OG1 3.37Å; M53-V65 CarbonylContact O-C 3.5Å; M53-V65 WeakPolarHBondContact O-CA 3.39Å; M53-G66 PolarHBondContact N-O 2.89Å; M53-G66 VanDerWaalsContact N-O 3.15Å; M53-G66 PolarHBondContact O-N 2.86Å; M53-I114 HydrophobicContact CB-CG2 4.46Å; M53-L117 HydrophobicContact CE-CB 4.36Å; M53-L117 WeakPolarHBondContact CE-O 3.44Å; M53-L117 HydrophobicContact CG-CB 3.79Å
54L97.6Very high94.1Very high11 Ų1155.2 Ų55.26%0.05829%0.288CS..EExtended strand (participates in β ladder)trans-120140.2173.2-66.9177.6000109.3L63 V65 S473 V491L54-L63 HydrophobicContact CB-CD1 4.48Å; L54-L63 HydrophobicContact CD2-CD1 4.41Å; L54-V65 HydrophobicContact CD2-CB 4.29Å; L54-V65 HydrophobicContact CD2-CG1 3.97Å; L54-V65 HydrophobicContact CD2-CG2 3.77Å; L54-S473 WeakPolarHBondContact CD1-OG 3.41Å; L54-S473 WeakPolarHBondContact CG-OG 3.46Å; L54-V491 HydrophobicContact CD2-CG1 4.12Å; L54-V491 HydrophobicContact CD2-CG2 4.21Å
55T96.2Very high94.2Very high18 Ų1851.7 Ų51.711%0.1126%0.263CS..EExtended strand (participates in β ladder)trans-152.5115-177.8-53.70000110.5M53 Y64 L117M53-T55 WeakPolarHBondContact CE-OG1 3.37Å; T55-Y64 PolarHBondContact N-O 3.18Å; T55-Y64 PolarHBondContact O-N 2.98Å; T55-L117 PolarHBondContact OG1-O 3.32Å; T55-L117 VanDerWaalsContact OG1-O 3.05Å
56L95Very high94.2Very high34 Ų3449.8 Ų49.818%0.17825%0.252CS..EExtended strand (participates in β ladder)trans-75139.7169.4-70167.2000109.8E60 L63 P76 T475 I476 Y484L56-E60 HydrophobicContact CB-CG 4.46Å; L56-E60 HydrophobicContact CD1-CG 4.18Å; L56-L63 HydrophobicContact CD2-CB 4.23Å; L56-L63 HydrophobicContact CD2-CD1 3.93Å; L56-L63 HydrophobicContact CG-CD1 4.28Å; L56-P76 HydrophobicContact CD2-CB 4.18Å; L56-P76 HydrophobicContact CD2-CG 4.25Å; L56-T475 HydrophobicContact CD1-CG2 3.85Å; L56-T475 HydrophobicContact CG-CG2 4Å; L56-I476 WeakPolarHBondContact CD1-O 3.45Å; L56-Y484 HydrophobicContact CD1-CD2 4.45Å; L56-Y484 HydrophobicContact CD1-CE2 4.1Å; L56-Y484 HydrophobicContact CD2-CD2 4.32Å; L56-Y484 HydrophobicContact CD2-CE2 3.82Å; L56-Y484 HydrophobicContact CG-CE2 4.4Å
57S90.9Very high94.4Very high21 Ų2140.3 Ų40.315%0.14721%0.207CC..PPolyproline II helixtrans-65.7166.2171.480.30000111.4H59 E60 R61 V62S57-H59 PolarHBondContact O-N 3.31Å; S57-E60 WeakPolarHBondContact O-CA 3.49Å; S57-E60 PolarHBondContact O-N 2.03Å; S57-R61 PolarHBondContact OG-N 3.22Å; S57-V62 PolarHBondContact N-O 3.38Å; S57-V62 PolarHBondContact OG-N 3.46Å; S57-V62 VanDerWaalsContact OG-N 3.12Å
58D79.5Confident94.5Very high98 Ų9839.9 Ų39.952%0.52419%0.19SC..G310 helixtrans-50.2135.4160.5-59.1-66.2000110.1E60 S119D58-E60 PolarHBondContact O-N 2.93Å; D58-S119 WeakPolarHBondContact OD2-CB 3.49Å; D58-S119 PolarHBondContact OD2-OG 2.83Å
59H81.9Confident94.6Very high163 Ų16340.4 Ų40.476%0.75519%0.191SC*.G310 helixtrans55.921.6-171-51.3-77.1000116.4S57 R61S57-H59 PolarHBondContact O-N 3.31Å; H59-R61 HydrophobicContact CB-CG 4.32Å; H59-R61 PolarHBondContact O-N 3.24Å; H59-R61 VanDerWaalsContact O-N 3.16Å
60E87.8Confident94.6Very high30 Ų3036.9 Ų36.914%0.1418%0.176CC..G310 helixtrans52.438.2174.1-53.7-178.5165.700113.4L56 S57 D58 S477 H478 S479 K480L56-E60 HydrophobicContact CB-CG 4.46Å; L56-E60 HydrophobicContact CD1-CG 4.18Å; S57-E60 WeakPolarHBondContact O-CA 3.49Å; S57-E60 PolarHBondContact O-N 2.03Å; D58-E60 PolarHBondContact O-N 2.93Å; E60-S477 VanDerWaalsContact CD-OG 3.31Å; E60-S477 WeakPolarHBondContact OE1-CA 3.02Å; E60-S477 WeakPolarHBondContact OE2-CB 3.14Å; E60-S477 PolarHBondContact OE2-OG 3.18Å; E60-H478 PolarHBondContact OE1-N 2.77Å; E60-S479 WeakPolarHBondContact OE2-CB 3.1Å; E60-S479 PolarHBondContact OE2-N 3.27Å; E60-S479 PolarHBondContact OE2-OG 3.36Å; E60-K480 WeakPolarHBondContact O-CE 3.44Å
61R90.6Very high94.6Very high183 Ų18335.6 Ų35.669%0.69117%0.169SC*.  trans-85.4-28.7-178.6-65.7-175.5178.7-179.51113.7S57 H59 P76S57-R61 PolarHBondContact OG-N 3.22Å; H59-R61 HydrophobicContact CB-CG 4.32Å; H59-R61 PolarHBondContact O-N 3.24Å; H59-R61 VanDerWaalsContact O-N 3.16Å; R61-P76 VanDerWaalsContact O-CD 3.26Å; R61-P76 WeakPolarHBondContact O-CD 3.14Å
62V95.3Very high94.7Very high24 Ų2435.6 Ų35.615%0.14517%0.169CC..  trans-135.6141179.8-173.40000109.1S57 Y64 A73 L83S57-V62 PolarHBondContact N-O 3.38Å; S57-V62 PolarHBondContact OG-N 3.46Å; S57-V62 VanDerWaalsContact OG-N 3.12Å; V62-Y64 HydrophobicContact CB-CE1 4.04Å; V62-Y64 HydrophobicContact CB-CE2 4.17Å; V62-Y64 HydrophobicContact CG1-CD1 3.71Å; V62-Y64 HydrophobicContact CG1-CE1 3.41Å; V62-Y64 VanDerWaalsContact CG1-CE1 3.41Å; V62-Y64 HydrophobicContact CG1-CE2 4.31Å; V62-Y64 HydrophobicContact CG1-CG 4.29Å; V62-A73 HydrophobicContact CG1-CB 3.74Å; V62-L83 HydrophobicContact CG1-CD1 4.34Å; V62-L83 HydrophobicContact CG2-CD1 4.03Å
63L97.6Very high94.8Very high0 Ų034.3 Ų34.30%016%0.16CC..EExtended strand (participates in β ladder)trans-101.7106.3167.6174.765.7000107.1L54 L56 V65 L74 P76 I79 Y484L54-L63 HydrophobicContact CB-CD1 4.48Å; L54-L63 HydrophobicContact CD2-CD1 4.41Å; L56-L63 HydrophobicContact CD2-CB 4.23Å; L56-L63 HydrophobicContact CD2-CD1 3.93Å; L56-L63 HydrophobicContact CG-CD1 4.28Å; L63-V65 HydrophobicContact CD2-CG2 4.46Å; L63-V65 HydrophobicContact CG-CG2 4.16Å; L63-L74 HydrophobicContact CB-CB 4.38Å; L63-L74 PolarHBondContact N-O 3.08Å; L63-L74 PolarHBondContact O-N 2.98Å; L63-P76 HydrophobicContact CB-CB 4.49Å; L63-P76 HydrophobicContact CB-CG 4.1Å; L63-I79 HydrophobicContact CD2-CG2 3.79Å; L63-Y484 HydrophobicContact CD1-CD2 4.42Å; L63-Y484 HydrophobicContact CD1-CG 4.36Å; L63-Y484 HydrophobicContact CD2-CD1 3.62Å; L63-Y484 HydrophobicContact CD2-CE1 4.19Å; L63-Y484 HydrophobicContact CD2-CG 3.8Å
64Y98.1Very high94.8Very high15 Ų1532.1 Ų32.16%0.05915%0.15CC..EExtended strand (participates in β ladder)trans-83136172.9-56.6-66.7000109.9T55 V62 F72 A73 L125 F145T55-Y64 PolarHBondContact N-O 3.18Å; T55-Y64 PolarHBondContact O-N 2.98Å; V62-Y64 HydrophobicContact CB-CE1 4.04Å; V62-Y64 HydrophobicContact CB-CE2 4.17Å; V62-Y64 HydrophobicContact CG1-CD1 3.71Å; V62-Y64 HydrophobicContact CG1-CE1 3.41Å; V62-Y64 VanDerWaalsContact CG1-CE1 3.41Å; V62-Y64 HydrophobicContact CG1-CE2 4.31Å; V62-Y64 HydrophobicContact CG1-CG 4.29Å; Y64-F72 WeakPolarHBondContact CA-O 3.42Å; Y64-A73 HydrophobicContact CD1-CB 3.93Å; Y64-A73 HydrophobicContact CE1-CB 3.98Å; Y64-L125 HydrophobicContact CD1-CD1 3.82Å; Y64-L125 HydrophobicContact CD2-CD1 3.87Å; Y64-L125 HydrophobicContact CD2-CD2 4.22Å; Y64-L125 HydrophobicContact CE1-CD1 3.75Å; Y64-L125 HydrophobicContact CE2-CD1 3.8Å; Y64-L125 HydrophobicContact CE2-CD2 3.66Å; Y64-L125 HydrophobicContact CE2-CG 4.35Å; Y64-L125 HydrophobicContact CG-CD1 3.86Å; Y64-F145 HydrophobicContact CD1-CD2 4.13Å; Y64-F145 AromaticContact CD1-CE2 3.4Å; Y64-F145 HydrophobicContact CD1-CE2 3.4Å; Y64-F145 HydrophobicContact CD1-CZ 4.03Å; Y64-F145 AromaticContact CE1-CD2 3.82Å; Y64-F145 HydrophobicContact CE1-CD2 3.82Å; Y64-F145 AromaticContact CE1-CE2 3.57Å; Y64-F145 HydrophobicContact CE1-CE2 3.57Å; Y64-F145 HydrophobicContact CG-CE2 4.49Å
65V98.6Very high94.8Very high0 Ų032.4 Ų32.40%015%0.151CC..EExtended strand (participates in β ladder)trans-126.9122.2-178-174.50000109Y51 M53 L54 L63 L71 F72 L74 V491Y51-V65 HydrophobicContact CD1-CG1 3.96Å; M53-V65 CarbonylContact O-C 3.5Å; M53-V65 WeakPolarHBondContact O-CA 3.39Å; L54-V65 HydrophobicContact CD2-CB 4.29Å; L54-V65 HydrophobicContact CD2-CG1 3.97Å; L54-V65 HydrophobicContact CD2-CG2 3.77Å; L63-V65 HydrophobicContact CD2-CG2 4.46Å; L63-V65 HydrophobicContact CG-CG2 4.16Å; V65-L71 CarbonylContact O-C 3.59Å; V65-L71 VanDerWaalsContact O-CA 3.28Å; V65-L71 WeakPolarHBondContact O-CA 3.39Å; V65-F72 HydrophobicContact CB-CB 4.25Å; V65-F72 HydrophobicContact CB-CD2 4.26Å; V65-F72 HydrophobicContact CG1-CD2 4.39Å; V65-F72 PolarHBondContact N-O 3.18Å; V65-F72 PolarHBondContact O-N 2.83Å; V65-L74 HydrophobicContact CG2-CD1 3.75Å; V65-L74 HydrophobicContact CG2-CG 4.2Å; V65-V491 HydrophobicContact CG1-CG2 3.85Å; V65-V491 HydrophobicContact CG2-CG2 4.34Å
66G98.4Very high94.8Very high0 Ų031.6 Ų31.60%015%0.146CC..EExtended strand (participates in β ladder)trans-97.9123168.300000110.3S52 M53S52-G66 PolarHBondContact N-O 3.41Å; M53-G66 PolarHBondContact N-O 2.89Å; M53-G66 VanDerWaalsContact N-O 3.15Å; M53-G66 PolarHBondContact O-N 2.86Å
67A98.3Very high94.7Very high0 Ų034 Ų340%016%0.159CC..  trans-114.9-165.6178.400000111.2V48 N50 Y51 T70 F72 I114V48-A67 HydrophobicContact CG1-CB 3.62Å; N50-A67 WeakPolarHBondContact O-CA 3.05Å; Y51-A67 HydrophobicContact CD1-CB 3.98Å; Y51-A67 HydrophobicContact CE1-CB 4.29Å; Y51-A67 HydrophobicContact CG-CB 4.39Å; A67-T70 PolarHBondContact N-O 3.12Å; A67-F72 HydrophobicContact CB-CE2 4.07Å; A67-I114 WeakPolarHBondContact O-CG1 3.39Å; A67-I114 PolarHBondContact O-N 3.06Å
68R97.9Very high94.9Very high43 Ų4336.1 Ų36.116%0.16217%0.169CC..BIsolated β-bridgetrans-78.4116.9165.6-167.5-175.875164.3-1109.8F49 N50 T70 Q107 F111 Y113F49-R68 WeakPolarHBondContact O-CB 3.45Å; F49-R68 PolarHBondContact O-N 2.92Å; N50-R68 HydrophobicContact CB-CB 4.42Å; R68-T70 PolarHBondContact O-N 3.05Å; R68-Q107 PolarHBondContact NH1-O 2.92Å; R68-F111 HydrophobicContact CG-CB 3.82Å; R68-F111 HydrophobicContact CG-CD1 4.45Å; R68-F111 HydrophobicContact CG-CG 4.26Å; R68-Y113 HydrophobicContact CB-CD1 4.14Å; R68-Y113 HydrophobicContact CB-CE1 3.93Å; R68-Y113 WeakPolarHBondContact CD-OH 3.22Å; R68-Y113 HydrophobicContact CG-CD1 4.07Å; R68-Y113 HydrophobicContact CG-CD2 4.31Å; R68-Y113 HydrophobicContact CG-CE1 3.74Å; R68-Y113 HydrophobicContact CG-CE2 3.99Å; R68-Y113 HydrophobicContact CG-CG 4.35Å
69E97.5Very high95.7Very high27 Ų2731.5 Ų31.513%0.12614%0.144CC..SBendtrans641.3178.9-50.7-149.8125.600117.2W89 P90 A91 K96 F111 N112E69-W89 CarbonylContact O-C 3.6Å; E69-W89 PolarHBondContact O-N 2.74Å; E69-P90 HydrophobicContact CB-CB 4.05Å; E69-P90 VanDerWaalsContact CD-CB 3.49Å; E69-P90 HydrophobicContact CG-CB 4.26Å; E69-P90 WeakPolarHBondContact OE1-CA 3.02Å; E69-A91 PolarHBondContact OE1-N 3.08Å; E69-K96 WeakPolarHBondContact OE1-CE 3.28Å; E69-K96 IonicContact OE1-NZ 2.69Å; E69-K96 PolarHBondContact OE1-NZ 2.86Å; E69-K96 IonicContact OE2-NZ 2.65Å; E69-K96 PolarHBondContact OE2-NZ 3.13Å; E69-F111 HydrophobicContact CG-CB 4.09Å; E69-F111 HydrophobicContact CG-CD1 4.13Å; E69-F111 WeakPolarHBondContact OE2-CD1 3.02Å; E69-N112 WeakPolarHBondContact CA-O 3.31Å; E69-N112 HydrophobicContact CG-CB 4.27Å; E69-N112 PolarHBondContact N-O 3.39Å; E69-N112 PolarHBondContact OE1-N 2.96Å; E69-N112 VanDerWaalsContact OE1-N 3.16Å
70T97.9Very high96.3Very high7 Ų727.2 Ų27.24%0.04313%0.133CC..EExtended strand (participates in β ladder)trans-139149-178-52.50000111.8A67 R68 F72 Q86 I87 D88A67-T70 PolarHBondContact N-O 3.12Å; R68-T70 PolarHBondContact O-N 3.05Å; T70-F72 HydrophobicContact CG2-CD1 4.33Å; T70-F72 HydrophobicContact CG2-CD2 4.46Å; T70-F72 HydrophobicContact CG2-CE1 3.68Å; T70-F72 HydrophobicContact CG2-CE2 3.84Å; T70-F72 HydrophobicContact CG2-CZ 3.42Å; T70-F72 VanDerWaalsContact CG2-CZ 3.42Å; T70-Q86 HydrophobicContact CG2-CB 3.85Å; T70-Q86 HydrophobicContact CG2-CG 4.01Å; T70-I87 CarbonylContact C-O 3.59Å; T70-I87 VanDerWaalsContact CA-O 3.3Å; T70-I87 WeakPolarHBondContact CA-O 3.44Å; T70-D88 WeakPolarHBondContact CG2-OD1 3.45Å; T70-D88 PolarHBondContact OG1-OD1 2.97Å
71L98.5Very high96.6Very high0 Ų032.6 Ų32.60%015%0.152CC..EExtended strand (participates in β ladder)trans-120.9147.1165.6-5199.2000111.9V65 Q86 I87 W89 I114 L117 I140 F145V65-L71 CarbonylContact O-C 3.59Å; V65-L71 VanDerWaalsContact O-CA 3.28Å; V65-L71 WeakPolarHBondContact O-CA 3.39Å; L71-Q86 WeakPolarHBondContact O-CA 3.39Å; L71-I87 HydrophobicContact CB-CB 4.28Å; L71-I87 HydrophobicContact CD1-CB 3.96Å; L71-I87 HydrophobicContact CD1-CG2 3.95Å; L71-I87 PolarHBondContact N-O 3.18Å; L71-I87 PolarHBondContact O-N 3.21Å; L71-W89 HydrophobicContact CD1-CB 4.38Å; L71-W89 HydrophobicContact CD1-CE3 4.24Å; L71-I114 HydrophobicContact CD1-CD1 4.09Å; L71-I114 HydrophobicContact CD1-CG1 4.42Å; L71-I114 HydrophobicContact CD2-CD1 4.29Å; L71-I114 HydrophobicContact CD2-CG1 4.19Å; L71-I114 HydrophobicContact CD2-CG2 4.17Å; L71-I114 HydrophobicContact CG-CD1 4.21Å; L71-I114 HydrophobicContact CG-CG1 4.04Å; L71-L117 HydrophobicContact CD2-CD1 3.9Å; L71-L117 HydrophobicContact CD2-CD2 4.03Å; L71-I140 HydrophobicContact CD2-CD1 3.9Å; L71-F145 HydrophobicContact CB-CE1 4.26Å; L71-F145 HydrophobicContact CB-CZ 4.05Å
72F98.3Very high96.9Very high0 Ų027 Ų270%013%0.134CC..EExtended strand (participates in β ladder)trans-126.6157.5179.1-50.6-85.4000112.1F43 V45 V48 Y51 Y64 V65 A67 T70 L74 Q86F43-F72 HydrophobicContact CE1-CB 4.43Å; F43-F72 AromaticContact CE1-CD1 3.94Å; F43-F72 HydrophobicContact CE1-CD1 3.94Å; F43-F72 AromaticContact CE1-CD2 4Å; F43-F72 HydrophobicContact CE1-CD2 4Å; F43-F72 HydrophobicContact CE1-CE1 4.14Å; F43-F72 HydrophobicContact CE1-CE2 4.19Å; F43-F72 AromaticContact CE1-CG 3.85Å; F43-F72 HydrophobicContact CE1-CG 3.85Å; F43-F72 HydrophobicContact CE1-CZ 4.25Å; F43-F72 HydrophobicContact CZ-CB 4.5Å; F43-F72 AromaticContact CZ-CD1 3.66Å; F43-F72 HydrophobicContact CZ-CD1 3.66Å; F43-F72 AromaticContact CZ-CE1 3.93Å; F43-F72 HydrophobicContact CZ-CE1 3.93Å; F43-F72 AromaticContact CZ-CG 3.99Å; F43-F72 HydrophobicContact CZ-CG 3.99Å; F43-F72 HydrophobicContact CZ-CZ 4.47Å; V45-F72 HydrophobicContact CB-CE1 4.35Å; V45-F72 HydrophobicContact CB-CZ 4.16Å; V45-F72 HydrophobicContact CG2-CE1 3.69Å; V45-F72 HydrophobicContact CG2-CZ 3.9Å; V48-F72 HydrophobicContact CB-CZ 4.39Å; V48-F72 HydrophobicContact CG1-CE2 3.96Å; V48-F72 HydrophobicContact CG1-CZ 3.94Å; V48-F72 HydrophobicContact CG2-CZ 4.33Å; Y51-F72 HydrophobicContact CD1-CE2 4.24Å; Y51-F72 HydrophobicContact CE1-CD2 4.42Å; Y51-F72 AromaticContact CE1-CE2 3.73Å; Y51-F72 HydrophobicContact CE1-CE2 3.73Å; Y51-F72 HydrophobicContact CE1-CZ 4.37Å; Y64-F72 WeakPolarHBondContact CA-O 3.42Å; V65-F72 HydrophobicContact CB-CB 4.25Å; V65-F72 HydrophobicContact CB-CD2 4.26Å; V65-F72 HydrophobicContact CG1-CD2 4.39Å; V65-F72 PolarHBondContact N-O 3.18Å; V65-F72 PolarHBondContact O-N 2.83Å; A67-F72 HydrophobicContact CB-CE2 4.07Å; T70-F72 HydrophobicContact CG2-CD1 4.33Å; T70-F72 HydrophobicContact CG2-CD2 4.46Å; T70-F72 HydrophobicContact CG2-CE1 3.68Å; T70-F72 HydrophobicContact CG2-CE2 3.84Å; T70-F72 HydrophobicContact CG2-CZ 3.42Å; T70-F72 VanDerWaalsContact CG2-CZ 3.42Å; F72-L74 HydrophobicContact CB-CD2 4.05Å; F72-L74 HydrophobicContact CB-CG 4.33Å; F72-Q86 HydrophobicContact CD1-CB 3.8Å; F72-Q86 HydrophobicContact CE1-CB 3.86Å
73A97.7Very high96.8Very high1 Ų127.8 Ų27.81%0.00814%0.137CC..EExtended strand (participates in β ladder)trans-127.2108.8170.400000108.5V62 Y64 L83 R84 F145V62-A73 HydrophobicContact CG1-CB 3.74Å; Y64-A73 HydrophobicContact CD1-CB 3.93Å; Y64-A73 HydrophobicContact CE1-CB 3.98Å; A73-L83 PolarHBondContact O-N 3.01Å; A73-R84 HydrophobicContact CB-CB 4.16Å; A73-R84 HydrophobicContact CB-CG 4.38Å; A73-F145 HydrophobicContact CB-CD1 4.1Å; A73-F145 HydrophobicContact CB-CD2 4.12Å; A73-F145 HydrophobicContact CB-CE1 4.07Å; A73-F145 HydrophobicContact CB-CE2 4.11Å; A73-F145 HydrophobicContact CB-CG 4.12Å; A73-F145 HydrophobicContact CB-CZ 4.08Å
74L97.7Very high96.7Very high0 Ų032.8 Ų32.80%016%0.156CC..EExtended strand (participates in β ladder)trans-110.6155.7-172.5-50.6-179.3000111.5F43 L63 V65 F72 P76 I79 Q82F43-L74 HydrophobicContact CB-CD1 4.12Å; F43-L74 HydrophobicContact CD1-CD1 3.7Å; F43-L74 HydrophobicContact CD1-CD2 4.3Å; F43-L74 HydrophobicContact CD2-CD1 4.15Å; F43-L74 HydrophobicContact CD2-CD2 3.82Å; F43-L74 HydrophobicContact CE1-CD1 4.15Å; F43-L74 HydrophobicContact CE1-CD2 4.07Å; F43-L74 HydrophobicContact CE2-CD2 3.57Å; F43-L74 HydrophobicContact CG-CD1 3.7Å; F43-L74 HydrophobicContact CG-CD2 4.19Å; F43-L74 HydrophobicContact CZ-CD2 3.71Å; L63-L74 HydrophobicContact CB-CB 4.38Å; L63-L74 PolarHBondContact N-O 3.08Å; L63-L74 PolarHBondContact O-N 2.98Å; V65-L74 HydrophobicContact CG2-CD1 3.75Å; V65-L74 HydrophobicContact CG2-CG 4.2Å; F72-L74 HydrophobicContact CB-CD2 4.05Å; F72-L74 HydrophobicContact CB-CG 4.33Å; L74-P76 WeakPolarHBondContact O-CD 3.43Å; L74-I79 HydrophobicContact CD1-CB 4.2Å; L74-Q82 HydrophobicContact CD2-CB 4.01Å; L74-Q82 HydrophobicContact CD2-CG 4.27Å
75D96.6Very high96.6Very high17 Ų1736.9 Ų36.99%0.09118%0.184CC..EExtended strand (participates in β ladder)trans-75.1117.2173.3-166.4-35.4000109.4N77 D78 I79 R81 L83D75-N77 PolarHBondContact O-N 3.47Å; D75-N77 VanDerWaalsContact O-N 3.11Å; D75-N77 WeakPolarHBondContact OD1-CB 3.22Å; D75-N77 PolarHBondContact OD1-N 3.45Å; D75-N77 PolarHBondContact OD1-ND2 3.1Å; D75-D78 CarbonylContact O-C 3.57Å; D75-D78 PolarHBondContact O-N 3.31Å; D75-D78 VanDerWaalsContact O-N 3.07Å; D75-D78 VanDerWaalsContact O-O 3.09Å; D75-I79 PolarHBondContact O-N 2.8Å; D75-R81 HydrophobicContact CB-CB 4.04Å; D75-R81 HydrophobicContact CB-CG 4.33Å; D75-R81 WeakPolarHBondContact CB-O 3.49Å; D75-R81 PolarHBondContact N-O 2.92Å; D75-R81 IonicContact OD2-CZ 2.74Å; D75-R81 IonicContact OD2-NH1 2.74Å; D75-R81 PolarHBondContact OD2-NH1 2.03Å; D75-L83 HydrophobicContact CB-CD1 4.15Å; D75-L83 HydrophobicContact CB-CD2 3.9Å; D75-L83 HydrophobicContact CB-CG 3.9Å
76P96.1Very high96.5Very high0 Ų040 Ų400%020%0.198CC..THydrogen-bonded Turntrans-69.5-9.9-177.4-18.332.1000113.7L56 R61 L63 L74 K480 Y484 Q493L56-P76 HydrophobicContact CD2-CB 4.18Å; L56-P76 HydrophobicContact CD2-CG 4.25Å; R61-P76 VanDerWaalsContact O-CD 3.26Å; R61-P76 WeakPolarHBondContact O-CD 3.14Å; L63-P76 HydrophobicContact CB-CB 4.49Å; L63-P76 HydrophobicContact CB-CG 4.1Å; L74-P76 WeakPolarHBondContact O-CD 3.43Å; P76-K480 HydrophobicContact CB-CD 3.87Å; P76-Y484 HydrophobicContact CB-CE1 4.46Å; P76-Y484 WeakPolarHBondContact CB-OH 3.25Å; P76-Y484 PolarHBondContact O-OH 2.85Å; P76-Q493 PolarHBondContact O-NE2 3.28Å
77N94.5Very high96.5Very high85 Ų8540.7 Ų40.746%0.45520%0.202SC..THydrogen-bonded Turntrans-83.4-29172.9-47.1-77.7000111.5D75 K480 Q493D75-N77 PolarHBondContact O-N 3.47Å; D75-N77 VanDerWaalsContact O-N 3.11Å; D75-N77 WeakPolarHBondContact OD1-CB 3.22Å; D75-N77 PolarHBondContact OD1-N 3.45Å; D75-N77 PolarHBondContact OD1-ND2 3.1Å; N77-K480 PolarHBondContact OD1-NZ 2.92Å; N77-Q493 PolarHBondContact O-NE2 2.93Å
78D94.7Very high96.4Very high66 Ų6645.4 Ų45.435%0.35323%0.227SC..EExtended strand (participates in β ladder)trans-152.396.1179.7169.912.2000109.3D75 S80 R81D75-D78 CarbonylContact O-C 3.57Å; D75-D78 PolarHBondContact O-N 3.31Å; D75-D78 VanDerWaalsContact O-N 3.07Å; D75-D78 VanDerWaalsContact O-O 3.09Å; D78-S80 VanDerWaalsContact CG-OG 3.3Å; D78-S80 PolarHBondContact O-N 3.48Å; D78-S80 VanDerWaalsContact O-N 3.09Å; D78-S80 VanDerWaalsContact OD1-CB 3.32Å; D78-S80 WeakPolarHBondContact OD1-CB 3.48Å; D78-S80 PolarHBondContact OD1-N 2.73Å; D78-S80 VanDerWaalsContact OD1-N 3.07Å; D78-S80 PolarHBondContact OD1-OG 2.71Å; D78-S80 PolarHBondContact OD2-OG 3.02Å; D78-R81 WeakPolarHBondContact O-CB 3.44Å; D78-R81 PolarHBondContact O-N 3.28Å
79I96.6Very high96.4Very high0 Ų043.8 Ų43.80%022%0.221CC..EExtended strand (participates in β ladder)trans-66-13.5-174.863.4164.8000114.1A41 F43 L63 L74 D75 R81 Y484 V491 L492 Q493A41-I79 HydrophobicContact CB-CG1 4.28Å; F43-I79 HydrophobicContact CB-CB 4.45Å; F43-I79 HydrophobicContact CB-CD1 4.05Å; F43-I79 HydrophobicContact CB-CG1 4.25Å; F43-I79 WeakPolarHBondContact CD2-O 3.06Å; L63-I79 HydrophobicContact CD2-CG2 3.79Å; L74-I79 HydrophobicContact CD1-CB 4.2Å; D75-I79 PolarHBondContact O-N 2.8Å; I79-R81 PolarHBondContact O-N 2.86Å; I79-Y484 HydrophobicContact CG2-CD1 3.9Å; I79-Y484 HydrophobicContact CG2-CE1 3.98Å; I79-V491 HydrophobicContact CD1-CB 4.25Å; I79-V491 HydrophobicContact CD1-CG1 3.95Å; I79-V491 VanDerWaalsContact CD1-O 3.3Å; I79-V491 WeakPolarHBondContact CD1-O 3.16Å; I79-L492 VanDerWaalsContact CD1-C 3.48Å; I79-Q493 HydrophobicContact CB-CB 4.46Å; I79-Q493 HydrophobicContact CD1-CB 3.72Å; I79-Q493 HydrophobicContact CG1-CB 3.74Å; I79-Q493 HydrophobicContact CG2-CB 3.96Å; I79-Q493 HydrophobicContact CG2-CG 4.46Å
80S93.4Very high96.4Very high74 Ų7445.5 Ų45.552%0.51724%0.235SC..EExtended strand (participates in β ladder)trans-66.7-23.8172.777.90000111.5D78 Q82D78-S80 VanDerWaalsContact CG-OG 3.3Å; D78-S80 PolarHBondContact O-N 3.48Å; D78-S80 VanDerWaalsContact O-N 3.09Å; D78-S80 VanDerWaalsContact OD1-CB 3.32Å; D78-S80 WeakPolarHBondContact OD1-CB 3.48Å; D78-S80 PolarHBondContact OD1-N 2.73Å; D78-S80 VanDerWaalsContact OD1-N 3.07Å; D78-S80 PolarHBondContact OD1-OG 2.71Å; D78-S80 PolarHBondContact OD2-OG 3.02Å; S80-Q82 PolarHBondContact O-N 3.17Å
81R95Very high96.3Very high142 Ų14245.2 Ų45.254%0.53623%0.233SC..EExtended strand (participates in β ladder)trans-88.7101.4178.5-172.4-172.1-176.1-1537.9111.5D75 D78 I79D75-R81 HydrophobicContact CB-CB 4.04Å; D75-R81 HydrophobicContact CB-CG 4.33Å; D75-R81 WeakPolarHBondContact CB-O 3.49Å; D75-R81 PolarHBondContact N-O 2.92Å; D75-R81 IonicContact OD2-CZ 2.74Å; D75-R81 IonicContact OD2-NH1 2.74Å; D75-R81 PolarHBondContact OD2-NH1 2.03Å; D78-R81 WeakPolarHBondContact O-CB 3.44Å; D78-R81 PolarHBondContact O-N 3.28Å; I79-R81 PolarHBondContact O-N 2.86Å
82Q95.3Very high96.1Very high66 Ų6647.4 Ų47.431%0.30825%0.247SC..EExtended strand (participates in β ladder)trans-70.8128.4167.4-178.7166.9-19.700111.1L74 S80 R84 Q86L74-Q82 HydrophobicContact CD2-CB 4.01Å; L74-Q82 HydrophobicContact CD2-CG 4.27Å; S80-Q82 PolarHBondContact O-N 3.17Å; Q82-R84 WeakPolarHBondContact CG-O 3.42Å; Q82-R84 PolarHBondContact NE2-O 3.15Å; Q82-Q86 VanDerWaalsContact NE2-N 3.15Å
83L95.1Very high96.1Very high41 Ų4153.6 Ų53.622%0.21528%0.276CS..  trans-91.5-19.5-173.9-72.1179.7000114.6V62 A73 D75V62-L83 HydrophobicContact CG1-CD1 4.34Å; V62-L83 HydrophobicContact CG2-CD1 4.03Å; A73-L83 PolarHBondContact O-N 3.01Å; D75-L83 HydrophobicContact CB-CD1 4.15Å; D75-L83 HydrophobicContact CB-CD2 3.9Å; D75-L83 HydrophobicContact CB-CG 3.9Å
84R94.7Very high96Very high105 Ų10557.4 Ų57.440%0.39630%0.296SS..SBendtrans-147.7155.3-179.2-63-66.4-173.7-79-3.9110.2A73 Q82 D143 F145A73-R84 HydrophobicContact CB-CB 4.16Å; A73-R84 HydrophobicContact CB-CG 4.38Å; Q82-R84 WeakPolarHBondContact CG-O 3.42Å; Q82-R84 PolarHBondContact NE2-O 3.15Å; R84-D143 PolarHBondContact NE-O 2.78Å; R84-D143 PolarHBondContact NH2-O 3.4Å; R84-D143 VanDerWaalsContact NH2-O 3.14Å; R84-F145 HydrophobicContact CB-CB 3.63Å; R84-F145 HydrophobicContact CB-CD1 4.33Å; R84-F145 HydrophobicContact CB-CG 4.23Å; R84-F145 HydrophobicContact CG-CB 3.83Å
85P95.4Very high95.9Very high100 Ų10060.1 Ų60.165%0.64931%0.308SS*.  trans-50.7149.9171.3-25.235.3000112.2F145P85-F145 WeakPolarHBondContact O-CD1 3.18Å
86Q96.6Very high96Very high65 Ų6560.5 Ų60.530%0.30431%0.309SS..  trans-73.6151.5178.172.3-170.953.300111T70 L71 F72 Q82 D88T70-Q86 HydrophobicContact CG2-CB 3.85Å; T70-Q86 HydrophobicContact CG2-CG 4.01Å; L71-Q86 WeakPolarHBondContact O-CA 3.39Å; F72-Q86 HydrophobicContact CD1-CB 3.8Å; F72-Q86 HydrophobicContact CE1-CB 3.86Å; Q82-Q86 VanDerWaalsContact NE2-N 3.15Å; Q86-D88 PolarHBondContact NE2-OD1 2.7Å; Q86-D88 PolarHBondContact NE2-OD2 3.18Å
87I97.9Very high96.1Very high15 Ų1568.8 Ų68.88%0.07734%0.341CS..EExtended strand (participates in β ladder)trans-98.1107.2170.8-58.2169.2000107.6T70 L71 W89 I140 F145 L147T70-I87 CarbonylContact C-O 3.59Å; T70-I87 VanDerWaalsContact CA-O 3.3Å; T70-I87 WeakPolarHBondContact CA-O 3.44Å; L71-I87 HydrophobicContact CB-CB 4.28Å; L71-I87 HydrophobicContact CD1-CB 3.96Å; L71-I87 HydrophobicContact CD1-CG2 3.95Å; L71-I87 PolarHBondContact N-O 3.18Å; L71-I87 PolarHBondContact O-N 3.21Å; I87-W89 HydrophobicContact CG2-CB 4.43Å; I87-W89 PolarHBondContact O-N 2.95Å; I87-I140 HydrophobicContact CD1-CB 4.39Å; I87-I140 HydrophobicContact CD1-CD1 3.87Å; I87-I140 HydrophobicContact CD1-CG1 3.93Å; I87-I140 HydrophobicContact CD1-CG2 3.57Å; I87-F145 HydrophobicContact CD1-CD1 3.65Å; I87-F145 HydrophobicContact CD1-CD2 4.29Å; I87-F145 HydrophobicContact CD1-CE1 3.6Å; I87-F145 HydrophobicContact CD1-CE2 4.23Å; I87-F145 HydrophobicContact CD1-CG 4.01Å; I87-F145 HydrophobicContact CD1-CZ 3.91Å; I87-F145 VanDerWaalsContact CD1-O 3.27Å; I87-F145 WeakPolarHBondContact CD1-O 3.13Å; I87-F145 HydrophobicContact CG1-CD1 3.66Å; I87-F145 HydrophobicContact CG1-CE1 3.71Å; I87-F145 HydrophobicContact CG1-CG 4.4Å; I87-F145 HydrophobicContact CG1-CZ 4.49Å; I87-F145 WeakPolarHBondContact CG1-O 3.34Å; I87-L147 HydrophobicContact CD1-CB 4.28Å; I87-L147 HydrophobicContact CG2-CB 3.89Å; I87-L147 HydrophobicContact CG2-CD1 4.35Å
88D97.2Very high96.2Very high99 Ų9967.4 Ų67.453%0.52933%0.331SS..EExtended strand (participates in β ladder)trans-81.2115.4168.1-64.3-44.5000109.5T70 Q86T70-D88 WeakPolarHBondContact CG2-OD1 3.45Å; T70-D88 PolarHBondContact OG1-OD1 2.97Å; Q86-D88 PolarHBondContact NE2-OD1 2.7Å; Q86-D88 PolarHBondContact NE2-OD2 3.18Å
89W97.1Very high96.3Very high9 Ų964.3 Ų64.33%0.03432%0.315CS..  trans-129.363.4179.1-172.129000110.9E69 L71 I87 N112 I114 T127 Y131 K136 L147 L152E69-W89 CarbonylContact O-C 3.6Å; E69-W89 PolarHBondContact O-N 2.74Å; L71-W89 HydrophobicContact CD1-CB 4.38Å; L71-W89 HydrophobicContact CD1-CE3 4.24Å; I87-W89 HydrophobicContact CG2-CB 4.43Å; I87-W89 PolarHBondContact O-N 2.95Å; W89-N112 VanDerWaalsContact CD2-ND2 3.34Å; W89-N112 WeakPolarHBondContact O-CB 3.47Å; W89-N112 PolarHBondContact O-ND2 2.84Å; W89-I114 HydrophobicContact CE3-CD1 3.49Å; W89-I114 VanDerWaalsContact CE3-CD1 3.49Å; W89-I114 HydrophobicContact CZ3-CD1 3.69Å; W89-T127 HydrophobicContact CE3-CG2 4.29Å; W89-T127 HydrophobicContact CH2-CG2 4.23Å; W89-T127 HydrophobicContact CZ3-CG2 3.64Å; W89-Y131 AromaticContact CD1-CE2 3.98Å; W89-Y131 AromaticContact NE1-CE2 3.49Å; W89-K136 WeakPolarHBondContact CH2-O 3.14Å; W89-K136 HydrophobicContact CZ2-CB 4.07Å; W89-L147 HydrophobicContact CD2-CD1 4.06Å; W89-L147 HydrophobicContact CE3-CD1 4.09Å; W89-L147 HydrophobicContact CG-CD1 4.43Å; W89-L152 HydrophobicContact CZ2-CD2 3.62Å
90P97Very high96.4Very high63 Ų6367.2 Ų67.241%0.40933%0.332SS..PPolyproline II helixtrans-72.4158.8177.931.8-36.9000112.8E69E69-P90 HydrophobicContact CB-CB 4.05Å; E69-P90 VanDerWaalsContact CD-CB 3.49Å; E69-P90 HydrophobicContact CG-CB 4.26Å; E69-P90 WeakPolarHBondContact OE1-CA 3.02Å
91A96.1Very high96.5Very high2 Ų268.3 Ų68.32%0.01734%0.34CS..PPolyproline II helixtrans-75.8133.116800000110.6E69 K96 N112 Y131 A132E69-A91 PolarHBondContact OE1-N 3.08Å; A91-K96 HydrophobicContact CB-CG 4.11Å; A91-K96 WeakPolarHBondContact O-CD 3.41Å; A91-K96 WeakPolarHBondContact O-CE 3.04Å; A91-N112 HydrophobicContact CB-CB 4.39Å; A91-Y131 HydrophobicContact CB-CD2 4.5Å; A91-A132 HydrophobicContact CB-CB 3.62Å
92P95.9Very high96.6Very high46 Ų4666.4 Ų66.430%0.29934%0.335SS..PPolyproline II helixtrans-57.5152.2178.4-29.937000114.5D94 K95 K96 Y131P92-D94 VanDerWaalsContact C-N 3.34Å; P92-D94 WeakPolarHBondContact CB-OD1 3.5Å; P92-D94 PolarHBondContact O-N 2.96Å; P92-K95 HydrophobicContact CB-CB 4.49Å; P92-K95 HydrophobicContact CB-CG 4.31Å; P92-K95 CarbonylContact O-C 3.51Å; P92-K95 WeakPolarHBondContact O-CA 3.36Å; P92-K95 PolarHBondContact O-N 2.86Å; P92-K96 WeakPolarHBondContact O-CG 3.37Å; P92-K96 PolarHBondContact O-N 3.22Å; P92-Y131 VanDerWaalsContact CD-OH 3.27Å; P92-Y131 WeakPolarHBondContact CD-OH 3.43Å; P92-Y131 HydrophobicContact CG-CE1 4.32Å; P92-Y131 WeakPolarHBondContact CG-OH 3.32Å
93Q96.6Very high96.6Very high130 Ų13066.7 Ų66.761%0.60736%0.357SS*.Hα-helixtrans-71.5-24.3-171.6-64-65.8-7.900114R97Q93-R97 WeakPolarHBondContact O-CB 3.15Å; Q93-R97 VanDerWaalsContact O-CG 3.29Å; Q93-R97 WeakPolarHBondContact O-CG 3.19Å; Q93-R97 PolarHBondContact O-N 3.17Å; Q93-R97 PolarHBondContact O-NE 2.82Å
94D96.8Very high96.6Very high80 Ų8066.8 Ų66.843%0.42836%0.355SS..Hα-helixtrans-64.2-48.5163.158.9-62000111.3P92 K96 R97 E98P92-D94 VanDerWaalsContact C-N 3.34Å; P92-D94 WeakPolarHBondContact CB-OD1 3.5Å; P92-D94 PolarHBondContact O-N 2.96Å; D94-K96 PolarHBondContact O-N 2.76Å; D94-R97 WeakPolarHBondContact O-CB 3.19Å; D94-R97 PolarHBondContact O-N 3.45Å; D94-R97 VanDerWaalsContact O-N 3.14Å; D94-E98 PolarHBondContact O-N 3.45Å
95K96.1Very high96.7Very high57 Ų5764.9 Ų64.925%0.24835%0.353CS..Hα-helixtrans-67.2-35.1179.6-60.4-44.3-165.5152.60113.5P92 E98 C99P92-K95 HydrophobicContact CB-CB 4.49Å; P92-K95 HydrophobicContact CB-CG 4.31Å; P92-K95 CarbonylContact O-C 3.51Å; P92-K95 WeakPolarHBondContact O-CA 3.36Å; P92-K95 PolarHBondContact O-N 2.86Å; K95-E98 WeakPolarHBondContact CD-OE2 3.33Å; K95-E98 IonicContact NZ-OE2 3.49Å; K95-E98 PolarHBondContact NZ-OE2 3.17Å; K95-E98 PolarHBondContact O-N 3.43Å; K95-C99 WeakPolarHBondContact O-CB 3.47Å; K95-C99 PolarHBondContact O-N 2.74Å
96K97.6Very high96.6Very high26 Ų2665 Ų6511%0.11335%0.348CS..Hα-helixtrans-62-45.1169-68.2-173.3168.8166.60111.7E69 A91 P92 D94 C99 V100 C110 A132E69-K96 WeakPolarHBondContact OE1-CE 3.28Å; E69-K96 IonicContact OE1-NZ 2.69Å; E69-K96 PolarHBondContact OE1-NZ 2.86Å; E69-K96 IonicContact OE2-NZ 2.65Å; E69-K96 PolarHBondContact OE2-NZ 3.13Å; A91-K96 HydrophobicContact CB-CG 4.11Å; A91-K96 WeakPolarHBondContact O-CD 3.41Å; A91-K96 WeakPolarHBondContact O-CE 3.04Å; P92-K96 WeakPolarHBondContact O-CG 3.37Å; P92-K96 PolarHBondContact O-N 3.22Å; D94-K96 PolarHBondContact O-N 2.76Å; K96-C99 PolarHBondContact O-N 2.81Å; K96-V100 VanDerWaalsContact O-CG2 3.29Å; K96-V100 WeakPolarHBondContact O-CG2 3.36Å; K96-V100 PolarHBondContact O-N 3.1Å; K96-C110 WeakPolarHBondContact CE-O 3.46Å; K96-C110 WeakPolarHBondContact CG-O 3.31Å; K96-A132 HydrophobicContact CG-CB 4.33Å
97R97.6Very high96.3Very high174 Ų17468.7 Ų68.766%0.65737%0.365SS*.Hα-helixtrans-64.2-39.8174.5-75.8175.7-67.6162.32.3112.5Q93 D94 V100 S101Q93-R97 WeakPolarHBondContact O-CB 3.15Å; Q93-R97 VanDerWaalsContact O-CG 3.29Å; Q93-R97 WeakPolarHBondContact O-CG 3.19Å; Q93-R97 PolarHBondContact O-N 3.17Å; Q93-R97 PolarHBondContact O-NE 2.82Å; D94-R97 WeakPolarHBondContact O-CB 3.19Å; D94-R97 PolarHBondContact O-N 3.45Å; D94-R97 VanDerWaalsContact O-N 3.14Å; R97-V100 PolarHBondContact O-N 3.02Å; R97-S101 WeakPolarHBondContact O-CB 3.37Å; R97-S101 PolarHBondContact O-N 2.84Å; R97-S101 PolarHBondContact O-OG 2.96Å
98E97.3Very high96.1Very high56 Ų5671 Ų7126%0.26238%0.38SS..Hα-helixtrans-61.9-45.4176.2-160.6-159.4131.200111.3D94 K95 V100 S101 K102 Q134D94-E98 PolarHBondContact O-N 3.45Å; K95-E98 WeakPolarHBondContact CD-OE2 3.33Å; K95-E98 IonicContact NZ-OE2 3.49Å; K95-E98 PolarHBondContact NZ-OE2 3.17Å; K95-E98 PolarHBondContact O-N 3.43Å; E98-V100 PolarHBondContact O-N 2.89Å; E98-S101 WeakPolarHBondContact CA-OG 3.45Å; E98-S101 PolarHBondContact O-N 2.89Å; E98-S101 PolarHBondContact O-OG 3.21Å; E98-K102 WeakPolarHBondContact O-CG 3.48Å; E98-K102 PolarHBondContact O-N 2.89Å; E98-K102 WeakPolarHBondContact OE1-CE 3.35Å; E98-K102 IonicContact OE1-NZ 2.74Å; E98-K102 PolarHBondContact OE1-NZ 2.8Å; E98-Q134 PolarHBondContact OE1-NE2 3.18Å; E98-Q134 VanDerWaalsContact OE1-NE2 3.1Å; E98-Q134 PolarHBondContact OE2-NE2 2.96Å
99C97.3Very high96Very high1 Ų168.4 Ų68.41%0.00737%0.365CS..Hα-helixtrans-57.6-47.4173.3173.50000112K95 K96 S101 K102 K104 C110 A132K95-C99 WeakPolarHBondContact O-CB 3.47Å; K95-C99 PolarHBondContact O-N 2.74Å; K96-C99 PolarHBondContact O-N 2.81Å; C99-S101 PolarHBondContact O-N 2.93Å; C99-K102 PolarHBondContact O-N 3.37Å; C99-K102 VanDerWaalsContact O-N 3.11Å; C99-K104 PolarHBondContact O-N 3.29Å; C99-C110 VanDerWaalsContact C-SG 3.53Å; C99-C110 HydrophobicContact CB-CB 3.73Å; C99-C110 WeakPolarHBondContact CB-SG 3.23Å; C99-C110 WeakPolarHBondContact SG-CA 3.4Å; C99-C110 WeakPolarHBondContact SG-CB 3.17Å; C99-C110 CovalentContact SG-SG 2.04Å; C99-C110 PolarHBondContact SG-SG 2.83Å; C99-A132 HydrophobicContact CB-CB 4.11Å
100V97.5Very high96Very high61 Ų6168.1 Ų68.137%0.3736%0.364SS..Hα-helixtrans-64.6-38.3177.5175.40000112.2K96 R97 E98 K102 G103 N106 C110K96-V100 VanDerWaalsContact O-CG2 3.29Å; K96-V100 WeakPolarHBondContact O-CG2 3.36Å; K96-V100 PolarHBondContact O-N 3.1Å; R97-V100 PolarHBondContact O-N 3.02Å; E98-V100 PolarHBondContact O-N 2.89Å; V100-K102 PolarHBondContact O-N 2.9Å; V100-G103 PolarHBondContact O-N 3.12Å; V100-N106 HydrophobicContact CG2-CB 3.53Å; V100-C110 HydrophobicContact CG2-CB 4.22Å
101S97.3Very high96.1Very high97 Ų9766.4 Ų66.468%0.67835%0.35SS*.Hα-helixtrans-64.8-20175.271.60000113.6R97 E98 C99 G103R97-S101 WeakPolarHBondContact O-CB 3.37Å; R97-S101 PolarHBondContact O-N 2.84Å; R97-S101 PolarHBondContact O-OG 2.96Å; E98-S101 WeakPolarHBondContact CA-OG 3.45Å; E98-S101 PolarHBondContact O-N 2.89Å; E98-S101 PolarHBondContact O-OG 3.21Å; C99-S101 PolarHBondContact O-N 2.93Å; S101-G103 VanDerWaalsContact C-N 3.28Å
102K95.6Very high96.2Very high101 Ų10166.3 Ų66.344%0.43935%0.35SS..THydrogen-bonded Turntrans-90.618.3171.7-63.2173.9-173.1175.30112.8E98 C99 V100 F184E98-K102 WeakPolarHBondContact O-CG 3.48Å; E98-K102 PolarHBondContact O-N 2.89Å; E98-K102 WeakPolarHBondContact OE1-CE 3.35Å; E98-K102 IonicContact OE1-NZ 2.74Å; E98-K102 PolarHBondContact OE1-NZ 2.8Å; C99-K102 PolarHBondContact O-N 3.37Å; C99-K102 VanDerWaalsContact O-N 3.11Å; V100-K102 PolarHBondContact O-N 2.9Å; K102-F184 HydrophobicContact CB-CE1 4.15Å; K102-F184 HydrophobicContact CB-CE2 4.15Å; K102-F184 HydrophobicContact CB-CZ 3.51Å; K102-F184 HydrophobicContact CD-CD2 4.36Å; K102-F184 HydrophobicContact CD-CE2 3.79Å; K102-F184 HydrophobicContact CD-CZ 3.94Å; K102-F184 HydrophobicContact CG-CZ 4.33Å
103G95.6Very high96.3Very high73 Ų7365 Ų6575%0.75334%0.339SS*.THydrogen-bonded Turntrans81.811.8172.800000115.7V100 S101V100-G103 PolarHBondContact O-N 3.12Å; S101-G103 VanDerWaalsContact C-N 3.28Å
104K96.5Very high96.4Very high43 Ų4358.9 Ų58.919%0.18731%0.31CS..  trans-93.1150.7-178-70.9-73.9-175.2169.80112.9C99 E109 F133 D162 F184C99-K104 PolarHBondContact O-N 3.29Å; K104-E109 HydrophobicContact CB-CB 4.29Å; K104-E109 HydrophobicContact CD-CB 4.43Å; K104-E109 HydrophobicContact CD-CG 4.47Å; K104-E109 WeakPolarHBondContact CD-OE1 3.18Å; K104-E109 VanDerWaalsContact CD-OE2 3.25Å; K104-E109 WeakPolarHBondContact CD-OE2 3.45Å; K104-E109 IonicContact NZ-OE1 3.66Å; K104-E109 PolarHBondContact NZ-OE1 2.83Å; K104-F133 HydrophobicContact CD-CE1 3.85Å; K104-F133 HydrophobicContact CD-CE2 4.07Å; K104-F133 HydrophobicContact CD-CZ 3.58Å; K104-F133 HydrophobicContact CG-CD1 4.47Å; K104-F133 HydrophobicContact CG-CE1 4.28Å; K104-F133 HydrophobicContact CG-CE2 4.35Å; K104-F133 HydrophobicContact CG-CZ 4.2Å; K104-D162 IonicContact NZ-OD2 3.7Å; K104-D162 PolarHBondContact NZ-OD2 3.38Å; K104-F184 HydrophobicContact CG-CZ 4Å
105N95.1Very high96.4Very high65 Ų6557.9 Ų57.935%0.34830%0.3SS..  trans-71.3126.3-171-172.8-54.7000113Q107 T108 E109 C110N105-Q107 VanDerWaalsContact C-N 3.34Å; N105-Q107 PolarHBondContact O-N 3.33Å; N105-Q107 WeakPolarHBondContact OD1-CA 3.21Å; N105-Q107 PolarHBondContact OD1-N 2.82Å; N105-T108 WeakPolarHBondContact CB-OG1 3.34Å; N105-T108 PolarHBondContact OD1-N 2.81Å; N105-T108 PolarHBondContact OD1-OG1 3.19Å; N105-E109 HydrophobicContact CB-CB 4.11Å; N105-E109 HydrophobicContact CB-CG 4.05Å; N105-E109 VanDerWaalsContact CB-OE2 3.31Å; N105-E109 WeakPolarHBondContact CB-OE2 3.31Å; N105-E109 PolarHBondContact N-OE2 2.85Å; N105-E109 WeakPolarHBondContact O-CB 3.47Å; N105-E109 PolarHBondContact O-N 2.94Å; N105-C110 PolarHBondContact O-N 3.14Å
106N94.1Very high96.5Very high102 Ų10255.5 Ų55.555%0.54529%0.29SS..THydrogen-bonded Turntrans-76.1-11.9-177.268.7-20.5000115.4V100 F111V100-N106 HydrophobicContact CG2-CB 3.53Å; N106-F111 VanDerWaalsContact O-CE2 3.28Å; N106-F111 WeakPolarHBondContact O-CE2 3.32Å; N106-F111 WeakPolarHBondContact O-CZ 3.36Å
107Q91.1Very high96.4Very high142 Ų14254.3 Ų54.366%0.66429%0.285SS*.THydrogen-bonded Turntrans-105.1-24.4179.6-67176.81.900113.2R68 N105 F111R68-Q107 PolarHBondContact NH1-O 2.92Å; N105-Q107 VanDerWaalsContact C-N 3.34Å; N105-Q107 PolarHBondContact O-N 3.33Å; N105-Q107 WeakPolarHBondContact OD1-CA 3.21Å; N105-Q107 PolarHBondContact OD1-N 2.82Å; Q107-F111 WeakPolarHBondContact O-CE2 3.29Å
108T92.9Very high96.3Very high64 Ų6448.8 Ų48.839%0.39327%0.267SS..THydrogen-bonded Turntrans-123.8-34.6-176.658.40000115.5N105 Y113N105-T108 WeakPolarHBondContact CB-OG1 3.34Å; N105-T108 PolarHBondContact OD1-N 2.81Å; N105-T108 PolarHBondContact OD1-OG1 3.19Å; T108-Y113 VanDerWaalsContact O-CE2 3.24Å; T108-Y113 WeakPolarHBondContact O-CE2 3.4Å; T108-Y113 PolarHBondContact O-OH 3.21Å
109E95.4Very high96.2Very high45 Ų4547.6 Ų47.621%0.2126%0.264CS..THydrogen-bonded Turntrans-101.1-42.3-169.6-74.6-178.411600113K104 N105 F111 F133K104-E109 HydrophobicContact CB-CB 4.29Å; K104-E109 HydrophobicContact CD-CB 4.43Å; K104-E109 HydrophobicContact CD-CG 4.47Å; K104-E109 WeakPolarHBondContact CD-OE1 3.18Å; K104-E109 VanDerWaalsContact CD-OE2 3.25Å; K104-E109 WeakPolarHBondContact CD-OE2 3.45Å; K104-E109 IonicContact NZ-OE1 3.66Å; K104-E109 PolarHBondContact NZ-OE1 2.83Å; N105-E109 HydrophobicContact CB-CB 4.11Å; N105-E109 HydrophobicContact CB-CG 4.05Å; N105-E109 VanDerWaalsContact CB-OE2 3.31Å; N105-E109 WeakPolarHBondContact CB-OE2 3.31Å; N105-E109 PolarHBondContact N-OE2 2.85Å; N105-E109 WeakPolarHBondContact O-CB 3.47Å; N105-E109 PolarHBondContact O-N 2.94Å; E109-F111 VanDerWaalsContact C-N 3.25Å; E109-F111 PolarHBondContact O-N 2.87Å; E109-F133 HydrophobicContact CB-CE2 3.84Å; E109-F133 HydrophobicContact CB-CZ 4.43Å; E109-F133 HydrophobicContact CG-CE2 4.45Å
110C97.6Very high96Very high2 Ų249.7 Ų49.71%0.01427%0.272CS..SBendtrans-82.958.5-173-610000113.7K96 C99 V100 N105 A132K96-C110 WeakPolarHBondContact CE-O 3.46Å; K96-C110 WeakPolarHBondContact CG-O 3.31Å; C99-C110 VanDerWaalsContact C-SG 3.53Å; C99-C110 HydrophobicContact CB-CB 3.73Å; C99-C110 WeakPolarHBondContact CB-SG 3.23Å; C99-C110 WeakPolarHBondContact SG-CA 3.4Å; C99-C110 WeakPolarHBondContact SG-CB 3.17Å; C99-C110 CovalentContact SG-SG 2.04Å; C99-C110 PolarHBondContact SG-SG 2.83Å; V100-C110 HydrophobicContact CG2-CB 4.22Å; N105-C110 PolarHBondContact O-N 3.14Å; C110-A132 HydrophobicContact CB-CB 4.37Å
111F97.9Very high95.6Very high28 Ų2848.6 Ų48.612%0.12327%0.265CS..SBendtrans-132.9165.1175.5-64.5-99000110.2R68 E69 N106 Q107 E109 Y113 T130 A132R68-F111 HydrophobicContact CG-CB 3.82Å; R68-F111 HydrophobicContact CG-CD1 4.45Å; R68-F111 HydrophobicContact CG-CG 4.26Å; E69-F111 HydrophobicContact CG-CB 4.09Å; E69-F111 HydrophobicContact CG-CD1 4.13Å; E69-F111 WeakPolarHBondContact OE2-CD1 3.02Å; N106-F111 VanDerWaalsContact O-CE2 3.28Å; N106-F111 WeakPolarHBondContact O-CE2 3.32Å; N106-F111 WeakPolarHBondContact O-CZ 3.36Å; Q107-F111 WeakPolarHBondContact O-CE2 3.29Å; E109-F111 VanDerWaalsContact C-N 3.25Å; E109-F111 PolarHBondContact O-N 2.87Å; F111-Y113 HydrophobicContact CB-CD2 4.16Å; F111-Y113 HydrophobicContact CB-CE2 3.84Å; F111-Y113 PolarHBondContact O-N 2.83Å; F111-T130 PolarHBondContact O-OG1 2.79Å; F111-A132 PolarHBondContact O-N 3.13Å
112N98.1Very high95.2Very high0 Ų052 Ų520%027%0.269CS..  trans-79.7108.1163.8-169.422.8000110.6E69 W89 A91 G129 T130 Y131E69-N112 WeakPolarHBondContact CA-O 3.31Å; E69-N112 HydrophobicContact CG-CB 4.27Å; E69-N112 PolarHBondContact N-O 3.39Å; E69-N112 PolarHBondContact OE1-N 2.96Å; E69-N112 VanDerWaalsContact OE1-N 3.16Å; W89-N112 VanDerWaalsContact CD2-ND2 3.34Å; W89-N112 WeakPolarHBondContact O-CB 3.47Å; W89-N112 PolarHBondContact O-ND2 2.84Å; A91-N112 HydrophobicContact CB-CB 4.39Å; N112-G129 VanDerWaalsContact OD1-CA 3.28Å; N112-G129 WeakPolarHBondContact OD1-CA 3.34Å; N112-T130 PolarHBondContact OD1-N 2.7Å; N112-Y131 HydrophobicContact CB-CD2 4.12Å; N112-Y131 WeakPolarHBondContact OD1-CA 3.31Å; N112-Y131 PolarHBondContact OD1-N 3.22Å
113Y98.4Very high95Very high19 Ų1949.3 Ų49.38%0.07526%0.262CS..BIsolated β-bridgetrans-96.7123.3168.4-76.2-94.1000108.9N50 R68 T108 F111 R115 G129 T130 P163N50-Y113 HydrophobicContact CB-CD1 4.23Å; N50-Y113 HydrophobicContact CB-CE1 3.78Å; R68-Y113 HydrophobicContact CB-CD1 4.14Å; R68-Y113 HydrophobicContact CB-CE1 3.93Å; R68-Y113 WeakPolarHBondContact CD-OH 3.22Å; R68-Y113 HydrophobicContact CG-CD1 4.07Å; R68-Y113 HydrophobicContact CG-CD2 4.31Å; R68-Y113 HydrophobicContact CG-CE1 3.74Å; R68-Y113 HydrophobicContact CG-CE2 3.99Å; R68-Y113 HydrophobicContact CG-CG 4.35Å; T108-Y113 VanDerWaalsContact O-CE2 3.24Å; T108-Y113 WeakPolarHBondContact O-CE2 3.4Å; T108-Y113 PolarHBondContact O-OH 3.21Å; F111-Y113 HydrophobicContact CB-CD2 4.16Å; F111-Y113 HydrophobicContact CB-CE2 3.84Å; F111-Y113 PolarHBondContact O-N 2.83Å; Y113-R115 PolarHBondContact O-N 3.16Å; Y113-G129 CarbonylContact O-C 3.55Å; Y113-G129 WeakPolarHBondContact O-CA 3.47Å; Y113-T130 PolarHBondContact N-OG1 2.75Å; Y113-T130 PolarHBondContact O-N 2.9Å; Y113-P163 HydrophobicContact CD1-CB 4.29Å; Y113-P163 HydrophobicContact CD2-CB 3.63Å; Y113-P163 HydrophobicContact CD2-CG 3.92Å; Y113-P163 HydrophobicContact CE2-CB 4.14Å; Y113-P163 HydrophobicContact CE2-CG 4.08Å; Y113-P163 HydrophobicContact CG-CB 3.72Å
114I98.4Very high95Very high0 Ų048.7 Ų48.70%024%0.239CC..EExtended strand (participates in β ladder)trans-69.4125173.1-53.9-57.9000108.9M53 A67 L71 W89M53-I114 HydrophobicContact CB-CG2 4.46Å; A67-I114 WeakPolarHBondContact O-CG1 3.39Å; A67-I114 PolarHBondContact O-N 3.06Å; L71-I114 HydrophobicContact CD1-CD1 4.09Å; L71-I114 HydrophobicContact CD1-CG1 4.42Å; L71-I114 HydrophobicContact CD2-CD1 4.29Å; L71-I114 HydrophobicContact CD2-CG1 4.19Å; L71-I114 HydrophobicContact CD2-CG2 4.17Å; L71-I114 HydrophobicContact CG-CD1 4.21Å; L71-I114 HydrophobicContact CG-CG1 4.04Å; W89-I114 HydrophobicContact CE3-CD1 3.49Å; W89-I114 VanDerWaalsContact CE3-CD1 3.49Å; W89-I114 HydrophobicContact CZ3-CD1 3.69Å
115R97.3Very high95Very high60 Ų6046.9 Ų46.923%0.22623%0.231CC..EExtended strand (participates in β ladder)trans-121.4-15.6-179-57.7-64.8-77.7-176.9-11.8113Y113 C128 T130 P160 P163 K165 H167Y113-R115 PolarHBondContact O-N 3.16Å; R115-C128 PolarHBondContact N-O 3.37Å; R115-T130 HydrophobicContact CG-CG2 3.9Å; R115-P160 HydrophobicContact CB-CG 4.38Å; R115-P160 HydrophobicContact CG-CG 4.02Å; R115-P163 PolarHBondContact NH1-O 2.92Å; R115-P163 PolarHBondContact NH2-O 3.06Å; R115-P163 VanDerWaalsContact NH2-O 3.08Å; R115-K165 PolarHBondContact NH2-O 3.33Å; R115-H167 PolarHBondContact O-CE1 3.46Å; R115-H167 VanDerWaalsContact O-CE1 3.27Å; R115-H167 PolarHBondContact O-ND1 3.14Å
116F97.5Very high95Very high6 Ų643.8 Ų43.83%0.02622%0.215CC..EExtended strand (participates in β ladder)trans-137.7138.9172.7-171.7-92000110.7Q118 Y126 T127 C128 I171 L176F116-Q118 HydrophobicContact CE1-CB 3.78Å; F116-Q118 HydrophobicContact CE2-CB 4.46Å; F116-Q118 HydrophobicContact CZ-CB 3.58Å; F116-Y126 AromaticContact CD1-CD1 3.94Å; F116-Y126 HydrophobicContact CD1-CD1 3.94Å; F116-Y126 AromaticContact CE1-CD1 3.88Å; F116-Y126 HydrophobicContact CE1-CD1 3.88Å; F116-T127 CarbonylContact O-C 3.5Å; F116-T127 VanDerWaalsContact O-CA 3.24Å; F116-T127 WeakPolarHBondContact O-CA 3.41Å; F116-T127 PolarHBondContact O-OG1 2.83Å; F116-C128 HydrophobicContact CB-CB 4.02Å; F116-C128 PolarHBondContact N-O 2.75Å; F116-C128 VanDerWaalsContact N-O 3.08Å; F116-C128 PolarHBondContact O-N 2.91Å; F116-I171 HydrophobicContact CE1-CD1 3.81Å; F116-I171 HydrophobicContact CE1-CG1 4.3Å; F116-I171 HydrophobicContact CZ-CD1 3.98Å; F116-I171 HydrophobicContact CZ-CG1 4.01Å; F116-L176 HydrophobicContact CD2-CD1 4.42Å; F116-L176 HydrophobicContact CE1-CD1 4.18Å; F116-L176 HydrophobicContact CE2-CD1 3.81Å; F116-L176 HydrophobicContact CZ-CD1 3.67Å
117L97.1Very high95.2Very high2 Ų239 Ų391%0.0119%0.189CC..EExtended strand (participates in β ladder)trans-158.4119.5175.8-174.958.5000107.7M53 T55 L71 L125 Y126 I140M53-L117 HydrophobicContact CE-CB 4.36Å; M53-L117 WeakPolarHBondContact CE-O 3.44Å; M53-L117 HydrophobicContact CG-CB 3.79Å; T55-L117 PolarHBondContact OG1-O 3.32Å; T55-L117 VanDerWaalsContact OG1-O 3.05Å; L71-L117 HydrophobicContact CD2-CD1 3.9Å; L71-L117 HydrophobicContact CD2-CD2 4.03Å; L117-L125 HydrophobicContact CD1-CB 4.5Å; L117-L125 HydrophobicContact CD1-CD1 4.2Å; L117-Y126 WeakPolarHBondContact CA-O 3.24Å; L117-I140 HydrophobicContact CD1-CD1 4Å
118Q95.5Very high95.5Very high58 Ų5832.2 Ų32.227%0.27116%0.157SC..EExtended strand (participates in β ladder)trans-155.4154.7176.8-162.4178.9-0.600111.5F116 Y120 L125 Y126 I171F116-Q118 HydrophobicContact CE1-CB 3.78Å; F116-Q118 HydrophobicContact CE2-CB 4.46Å; F116-Q118 HydrophobicContact CZ-CB 3.58Å; Q118-Y120 PolarHBondContact O-N 3.46Å; Q118-L125 CarbonylContact O-C 3.54Å; Q118-L125 VanDerWaalsContact O-CA 3.24Å; Q118-L125 WeakPolarHBondContact O-CA 2.93Å; Q118-L125 WeakPolarHBondContact O-CB 2.96Å; Q118-Y126 PolarHBondContact N-O 2.98Å; Q118-Y126 PolarHBondContact O-N 3.08Å; Q118-I171 HydrophobicContact CB-CD1 4.35Å
119S93.8Very high95.8Very high30 Ų3029.1 Ų29.121%0.2114%0.139CC..EExtended strand (participates in β ladder)trans-54.7123.7163.4-169.10000109.8D58D58-S119 WeakPolarHBondContact OD2-CB 3.49Å; D58-S119 PolarHBondContact OD2-OG 2.83Å
120Y92.9Very high95.9Very high46 Ų4627 Ų2718%0.1813%0.128CC..EExtended strand (participates in β ladder)trans-100.2-36.3173.3171-97.6000110.5Q118 H124 Y139 I171 K174 L195Q118-Y120 PolarHBondContact O-N 3.46Å; Y120-H124 WeakPolarHBondContact CA-O 3.28Å; Y120-H124 WeakPolarHBondContact CB-O 3.37Å; Y120-H124 PolarHBondContact N-O 2.88Å; Y120-Y139 HydrophobicContact CD1-CD1 4.01Å; Y120-Y139 AromaticContact CD1-CE1 3.65Å; Y120-Y139 HydrophobicContact CD1-CE1 3.65Å; Y120-Y139 HydrophobicContact CD2-CE1 4.02Å; Y120-Y139 HydrophobicContact CE1-CD1 4.41Å; Y120-Y139 AromaticContact CE1-CE1 3.73Å; Y120-Y139 HydrophobicContact CE1-CE1 3.73Å; Y120-Y139 HydrophobicContact CE2-CE1 4.06Å; Y120-Y139 HydrophobicContact CG-CD1 4.27Å; Y120-Y139 AromaticContact CG-CE1 3.83Å; Y120-Y139 HydrophobicContact CG-CE1 3.83Å; Y120-Y139 AromaticContact CZ-CE1 3.94Å; Y120-I171 HydrophobicContact CD2-CD1 4.1Å; Y120-I171 HydrophobicContact CD2-CG2 4.28Å; Y120-K174 HydrophobicContact CE2-CB 3.8Å; Y120-K174 HydrophobicContact CE2-CG 4.38Å; Y120-K174 WeakPolarHBondContact CE2-O 3.31Å; Y120-L195 HydrophobicContact CD2-CD1 4.42Å; Y120-L195 HydrophobicContact CE2-CD1 4.22Å
121N90.4Very high95.9Very high38 Ų3828.2 Ų28.220%0.20313%0.133CC..EExtended strand (participates in β ladder)trans-159.9178.7164.466.260.5000110.2T123 H124N121-T123 PolarHBondContact O-N 2.83Å; N121-T123 PolarHBondContact OD1-N 2.89Å; N121-T123 PolarHBondContact OD1-OG1 3.1Å; N121-H124 PolarHBondContact N-O 3.17Å; N121-H124 CarbonylContact O-C 3.41Å; N121-H124 PolarHBondContact O-N 3.11Å; N121-H124 PolarHBondContact OD1-N 2.82Å
122H88.8Confident95.9Very high167 Ų16726.9 Ų26.977%0.77313%0.127SC*.THydrogen-bonded Turntrans-57.7-16.7-176.964-91.2000116.6
123T91.6Very high95.8Very high46 Ų4627 Ų2728%0.28213%0.128SC..THydrogen-bonded Turntrans-110-12.9173.244.70000113.9N121 K141 A142N121-T123 PolarHBondContact O-N 2.83Å; N121-T123 PolarHBondContact OD1-N 2.89Å; N121-T123 PolarHBondContact OD1-OG1 3.1Å; T123-K141 CarbonylContact O-C 3.56Å; T123-K141 WeakPolarHBondContact O-CA 3.49Å; T123-A142 PolarHBondContact O-N 3.03Å
124H94.1Very high95.7Very high59 Ų5927.7 Ų27.727%0.27313%0.132SC..EExtended strand (participates in β ladder)trans-139.1131.9-169.9-67.879.3000113Y120 N121 I140Y120-H124 WeakPolarHBondContact CA-O 3.28Å; Y120-H124 WeakPolarHBondContact CB-O 3.37Å; Y120-H124 PolarHBondContact N-O 2.88Å; N121-H124 PolarHBondContact N-O 3.17Å; N121-H124 CarbonylContact O-C 3.41Å; N121-H124 PolarHBondContact O-N 3.11Å; N121-H124 PolarHBondContact OD1-N 2.82Å; H124-I140 CarbonylContact C-O 3.6Å; H124-I140 VanDerWaalsContact CA-O 3.28Å; H124-I140 WeakPolarHBondContact CA-O 3.2Å
125L96.1Very high95.7Very high6 Ų627.8 Ų27.83%0.03113%0.132CC..EExtended strand (participates in β ladder)trans-86.7161.4159.1-39.8176.8000109.3Y64 L117 Q118 Y139 I140 F145Y64-L125 HydrophobicContact CD1-CD1 3.82Å; Y64-L125 HydrophobicContact CD2-CD1 3.87Å; Y64-L125 HydrophobicContact CD2-CD2 4.22Å; Y64-L125 HydrophobicContact CE1-CD1 3.75Å; Y64-L125 HydrophobicContact CE2-CD1 3.8Å; Y64-L125 HydrophobicContact CE2-CD2 3.66Å; Y64-L125 HydrophobicContact CE2-CG 4.35Å; Y64-L125 HydrophobicContact CG-CD1 3.86Å; L117-L125 HydrophobicContact CD1-CB 4.5Å; L117-L125 HydrophobicContact CD1-CD1 4.2Å; Q118-L125 CarbonylContact O-C 3.54Å; Q118-L125 VanDerWaalsContact O-CA 3.24Å; Q118-L125 WeakPolarHBondContact O-CA 2.93Å; Q118-L125 WeakPolarHBondContact O-CB 2.96Å; L125-Y139 VanDerWaalsContact O-CA 3.3Å; L125-Y139 WeakPolarHBondContact O-CA 3.22Å; L125-I140 HydrophobicContact CB-CB 4.19Å; L125-I140 HydrophobicContact CD1-CB 4.45Å; L125-I140 HydrophobicContact CD1-CG2 4.46Å; L125-I140 PolarHBondContact N-O 3.13Å; L125-I140 PolarHBondContact O-N 2.73Å; L125-F145 HydrophobicContact CD1-CE2 3.98Å
126Y96.6Very high95.7Very high0 Ų027.2 Ų27.20%013%0.131CC..EExtended strand (participates in β ladder)trans-122.1136.5166.3-178-94.5000109.2F116 L117 Q118 C128 C137 Y139 E153 K158 I171 L176 L195F116-Y126 AromaticContact CD1-CD1 3.94Å; F116-Y126 HydrophobicContact CD1-CD1 3.94Å; F116-Y126 AromaticContact CE1-CD1 3.88Å; F116-Y126 HydrophobicContact CE1-CD1 3.88Å; L117-Y126 WeakPolarHBondContact CA-O 3.24Å; Q118-Y126 PolarHBondContact N-O 2.98Å; Q118-Y126 PolarHBondContact O-N 3.08Å; Y126-C128 WeakPolarHBondContact CE1-SG 3.41Å; Y126-C137 HydrophobicContact CE1-CB 3.99Å; Y126-C137 HydrophobicContact CE2-CB 4.05Å; Y126-C137 VanDerWaalsContact CZ-CB 3.45Å; Y126-C137 WeakPolarHBondContact OH-CB 3.3Å; Y126-C137 PolarHBondContact OH-SG 3.28Å; Y126-C137 VanDerWaalsContact OH-SG 3.33Å; Y126-Y139 AromaticContact CD2-CD1 3.8Å; Y126-Y139 HydrophobicContact CD2-CD1 3.8Å; Y126-Y139 HydrophobicContact CD2-CD2 4.34Å; Y126-Y139 AromaticContact CD2-CE1 3.5Å; Y126-Y139 HydrophobicContact CD2-CE1 3.5Å; Y126-Y139 VanDerWaalsContact CD2-CE1 3.5Å; Y126-Y139 HydrophobicContact CD2-CE2 4.06Å; Y126-Y139 HydrophobicContact CD2-CG 4.2Å; Y126-Y139 AromaticContact CD2-CZ 3.62Å; Y126-Y139 HydrophobicContact CE2-CE1 4.24Å; Y126-Y139 HydrophobicContact CE2-CE2 4.14Å; Y126-Y139 AromaticContact CE2-CZ 3.88Å; Y126-Y139 HydrophobicContact CG-CE1 4.36Å; Y126-E153 PolarHBondContact OH-OE2 3.02Å; Y126-K158 WeakPolarHBondContact OH-CD 3.48Å; Y126-K158 PolarHBondContact OH-NZ 2.85Å; Y126-K158 VanDerWaalsContact OH-NZ 3.07Å; Y126-I171 HydrophobicContact CD1-CD1 4.29Å; Y126-I171 HydrophobicContact CG-CD1 4.39Å; Y126-L176 HydrophobicContact CE1-CD2 3.85Å; Y126-L195 HydrophobicContact CD1-CD1 4.18Å; Y126-L195 HydrophobicContact CD2-CD1 4.04Å; Y126-L195 HydrophobicContact CE1-CD1 3.96Å; Y126-L195 HydrophobicContact CE2-CD1 3.78Å; Y126-L195 HydrophobicContact CE2-CD2 4.09Å; Y126-L195 HydrophobicContact CG-CD1 4.21Å
127T97.8Very high95.7Very high0 Ų027 Ų270%013%0.13CC..EExtended strand (participates in β ladder)trans-132.1150.6-176.7-173.40000111.6W89 F116 C137 N138 I140 L147W89-T127 HydrophobicContact CE3-CG2 4.29Å; W89-T127 HydrophobicContact CH2-CG2 4.23Å; W89-T127 HydrophobicContact CZ3-CG2 3.64Å; F116-T127 CarbonylContact O-C 3.5Å; F116-T127 VanDerWaalsContact O-CA 3.24Å; F116-T127 WeakPolarHBondContact O-CA 3.41Å; F116-T127 PolarHBondContact O-OG1 2.83Å; T127-C137 CarbonylContact O-C 3.6Å; T127-C137 WeakPolarHBondContact O-CA 3.31Å; T127-C137 VanDerWaalsContact O-CB 3.28Å; T127-C137 WeakPolarHBondContact O-CB 3.19Å; T127-N138 HydrophobicContact CG2-CB 4.46Å; T127-N138 PolarHBondContact N-O 2.77Å; T127-N138 PolarHBondContact O-N 2.94Å; T127-I140 HydrophobicContact CG2-CD1 3.7Å; T127-I140 HydrophobicContact CG2-CG1 3.99Å; T127-L147 HydrophobicContact CG2-CD1 4.08Å
128C97.7Very high95.6Very high0 Ų027.1 Ų27.10%013%0.131CC..EExtended strand (participates in β ladder)trans-139.2149.8168-54.40000111.5R115 F116 Y126 K136 C137 C159R115-C128 PolarHBondContact N-O 3.37Å; F116-C128 HydrophobicContact CB-CB 4.02Å; F116-C128 PolarHBondContact N-O 2.75Å; F116-C128 VanDerWaalsContact N-O 3.08Å; F116-C128 PolarHBondContact O-N 2.91Å; Y126-C128 WeakPolarHBondContact CE1-SG 3.41Å; C128-K136 VanDerWaalsContact CA-O 3.25Å; C128-K136 WeakPolarHBondContact CA-O 3.35Å; C128-C137 HydrophobicContact CB-CB 4.03Å; C128-C137 WeakPolarHBondContact CB-SG 3.27Å; C128-C137 WeakPolarHBondContact SG-CB 3.26Å; C128-C137 CovalentContact SG-SG 2.04Å; C128-C137 PolarHBondContact SG-SG 3.09Å; C128-C159 HydrophobicContact CB-CB 3.6Å
129G97.9Very high95.6Very high0 Ų027.2 Ų27.20%013%0.129CC..EExtended strand (participates in β ladder)trans-145164.1172.200000113.8N112 Y113 Y131 P135 K136N112-G129 VanDerWaalsContact OD1-CA 3.28Å; N112-G129 WeakPolarHBondContact OD1-CA 3.34Å; Y113-G129 CarbonylContact O-C 3.55Å; Y113-G129 WeakPolarHBondContact O-CA 3.47Å; G129-Y131 PolarHBondContact O-N 2.77Å; G129-P135 WeakPolarHBondContact O-CA 3.46Å; G129-K136 PolarHBondContact N-O 2.68Å; G129-K136 PolarHBondContact O-N 3.12Å; G129-K136 VanDerWaalsContact O-N 3.11Å
130T98Very high95.8Very high0 Ų025.8 Ų25.80%012%0.119CC..  trans-63.3-24.7-174.659.70000113.5F111 N112 Y113 R115 A132 F133 Q134 P160 P163F111-T130 PolarHBondContact O-OG1 2.79Å; N112-T130 PolarHBondContact OD1-N 2.7Å; Y113-T130 PolarHBondContact N-OG1 2.75Å; Y113-T130 PolarHBondContact O-N 2.9Å; R115-T130 HydrophobicContact CG-CG2 3.9Å; T130-A132 VanDerWaalsContact C-N 3.3Å; T130-A132 PolarHBondContact O-N 3.05Å; T130-F133 PolarHBondContact O-N 2.77Å; T130-Q134 CarbonylContact O-C 3.37Å; T130-Q134 PolarHBondContact O-N 2.96Å; T130-P160 WeakPolarHBondContact CG2-O 3.12Å; T130-P163 HydrophobicContact CG2-CB 4.14Å
131Y97.6Very high95.9Very high28 Ų2828.3 Ų28.311%0.1113%0.131CC..THydrogen-bonded Turntrans45.448.2175-153-107.3000114W89 A91 P92 N112 G129 Q134 K136W89-Y131 AromaticContact CD1-CE2 3.98Å; W89-Y131 AromaticContact NE1-CE2 3.49Å; A91-Y131 HydrophobicContact CB-CD2 4.5Å; P92-Y131 VanDerWaalsContact CD-OH 3.27Å; P92-Y131 WeakPolarHBondContact CD-OH 3.43Å; P92-Y131 HydrophobicContact CG-CE1 4.32Å; P92-Y131 WeakPolarHBondContact CG-OH 3.32Å; N112-Y131 HydrophobicContact CB-CD2 4.12Å; N112-Y131 WeakPolarHBondContact OD1-CA 3.31Å; N112-Y131 PolarHBondContact OD1-N 3.22Å; G129-Y131 PolarHBondContact O-N 2.77Å; Y131-Q134 PolarHBondContact O-N 2.55Å; Y131-K136 HydrophobicContact CD1-CB 4.48Å; Y131-K136 HydrophobicContact CD1-CG 3.74Å; Y131-K136 HydrophobicContact CE1-CG 4.14Å; Y131-K136 HydrophobicContact CG-CB 4.28Å; Y131-K136 HydrophobicContact CG-CG 4.01Å
132A97.5Very high96Very high0 Ų027.4 Ų27.40%013%0.129CC..THydrogen-bonded Turntrans53.458-172.700000113.5A91 K96 C99 C110 F111 T130 Q134A91-A132 HydrophobicContact CB-CB 3.62Å; K96-A132 HydrophobicContact CG-CB 4.33Å; C99-A132 HydrophobicContact CB-CB 4.11Å; C110-A132 HydrophobicContact CB-CB 4.37Å; F111-A132 PolarHBondContact O-N 3.13Å; T130-A132 VanDerWaalsContact C-N 3.3Å; T130-A132 PolarHBondContact O-N 3.05Å; A132-Q134 VanDerWaalsContact C-N 3.3Å; A132-Q134 PolarHBondContact O-N 3.41Å
133F97.1Very high96.1Very high3 Ų324.6 Ų24.61%0.01312%0.12CC..THydrogen-bonded Turntrans60.534.2-179.6-73.3-112.6000113.9K104 E109 T130 Y161 D162 F184K104-F133 HydrophobicContact CD-CE1 3.85Å; K104-F133 HydrophobicContact CD-CE2 4.07Å; K104-F133 HydrophobicContact CD-CZ 3.58Å; K104-F133 HydrophobicContact CG-CD1 4.47Å; K104-F133 HydrophobicContact CG-CE1 4.28Å; K104-F133 HydrophobicContact CG-CE2 4.35Å; K104-F133 HydrophobicContact CG-CZ 4.2Å; E109-F133 HydrophobicContact CB-CE2 3.84Å; E109-F133 HydrophobicContact CB-CZ 4.43Å; E109-F133 HydrophobicContact CG-CE2 4.45Å; T130-F133 PolarHBondContact O-N 2.77Å; F133-Y161 WeakPolarHBondContact CA-O 3.38Å; F133-Y161 WeakPolarHBondContact CG-O 3.38Å; F133-Y161 WeakPolarHBondContact O-CD1 3.39Å; F133-D162 HydrophobicContact CD1-CB 4.45Å; F133-D162 HydrophobicContact CE1-CB 3.47Å; F133-D162 VanDerWaalsContact CE1-CB 3.47Å; F133-D162 WeakPolarHBondContact CE1-OD2 3.3Å; F133-D162 VanDerWaalsContact CZ-CA 3.48Å; F133-D162 HydrophobicContact CZ-CB 3.64Å; F133-D162 VanDerWaalsContact CZ-CG 3.45Å; F133-D162 WeakPolarHBondContact CZ-OD2 3.43Å; F133-F184 HydrophobicContact CB-CD2 3.76Å; F133-F184 HydrophobicContact CB-CE2 3.52Å; F133-F184 AromaticContact CD1-CD2 3.92Å; F133-F184 HydrophobicContact CD1-CD2 3.92Å; F133-F184 AromaticContact CD1-CE2 3.7Å; F133-F184 HydrophobicContact CD1-CE2 3.7Å; F133-F184 HydrophobicContact CD1-CZ 4.2Å; F133-F184 HydrophobicContact CG-CD2 4.29Å; F133-F184 AromaticContact CG-CE2 3.89Å; F133-F184 HydrophobicContact CG-CE2 3.89Å
134Q96.8Very high96.1Very high33 Ų3325.7 Ų25.715%0.15412%0.124CC..SBendtrans-142.464.9174-61.7-175.339.700110.3E98 T130 Y131 A132 K136E98-Q134 PolarHBondContact OE1-NE2 3.18Å; E98-Q134 VanDerWaalsContact OE1-NE2 3.1Å; E98-Q134 PolarHBondContact OE2-NE2 2.96Å; T130-Q134 CarbonylContact O-C 3.37Å; T130-Q134 PolarHBondContact O-N 2.96Å; Y131-Q134 PolarHBondContact O-N 2.55Å; A132-Q134 VanDerWaalsContact C-N 3.3Å; A132-Q134 PolarHBondContact O-N 3.41Å; Q134-K136 WeakPolarHBondContact O-CE 3.42Å; Q134-K136 WeakPolarHBondContact O-CG 3.18Å; Q134-K136 PolarHBondContact O-N 3.38Å
135P97.2Very high96.2Very high1 Ų123.2 Ų23.21%0.00611%0.112CC..  trans-50.3132.3-161.5-30.937.7000114.2G129 G155 C159 P160 Y161G129-P135 WeakPolarHBondContact O-CA 3.46Å; P135-G155 VanDerWaalsContact O-CA 3.26Å; P135-G155 WeakPolarHBondContact O-CA 3.29Å; P135-G155 PolarHBondContact O-N 3.48Å; P135-C159 HydrophobicContact CB-CB 4.07Å; P135-P160 VanDerWaalsContact CG-O 3.29Å; P135-P160 WeakPolarHBondContact CG-O 3.42Å; P135-Y161 VanDerWaalsContact CD-CD1 3.49Å; P135-Y161 VanDerWaalsContact CD-CE1 3.5Å; P135-Y161 HydrophobicContact CG-CD1 4.19Å; P135-Y161 HydrophobicContact CG-CD2 3.85Å; P135-Y161 HydrophobicContact CG-CE1 4.42Å; P135-Y161 HydrophobicContact CG-CE2 4.11Å; P135-Y161 HydrophobicContact CG-CG 3.87Å
136K97.5Very high96.1Very high49 Ų4925.8 Ų25.821%0.21313%0.128CC..EExtended strand (participates in β ladder)trans-127.5155.7176.2-62.1-58.7157.2-167.20111.3W89 C128 G129 Y131 Q134 L152 E153 D154W89-K136 WeakPolarHBondContact CH2-O 3.14Å; W89-K136 HydrophobicContact CZ2-CB 4.07Å; C128-K136 VanDerWaalsContact CA-O 3.25Å; C128-K136 WeakPolarHBondContact CA-O 3.35Å; G129-K136 PolarHBondContact N-O 2.68Å; G129-K136 PolarHBondContact O-N 3.12Å; G129-K136 VanDerWaalsContact O-N 3.11Å; Y131-K136 HydrophobicContact CD1-CB 4.48Å; Y131-K136 HydrophobicContact CD1-CG 3.74Å; Y131-K136 HydrophobicContact CE1-CG 4.14Å; Y131-K136 HydrophobicContact CG-CB 4.28Å; Y131-K136 HydrophobicContact CG-CG 4.01Å; Q134-K136 WeakPolarHBondContact O-CE 3.42Å; Q134-K136 WeakPolarHBondContact O-CG 3.18Å; Q134-K136 PolarHBondContact O-N 3.38Å; K136-L152 HydrophobicContact CB-CD2 4.27Å; K136-E153 WeakPolarHBondContact CA-O 3.42Å; K136-E153 WeakPolarHBondContact CD-O 3.24Å; K136-D154 IonicContact NZ-OD1 2.7Å; K136-D154 PolarHBondContact NZ-OD1 2.64Å
137C97.1Very high96.1Very high0 Ų027.1 Ų27.10%014%0.135CC..EExtended strand (participates in β ladder)trans-130.7161176-55.20000111Y126 T127 C128 E153 G155Y126-C137 HydrophobicContact CE1-CB 3.99Å; Y126-C137 HydrophobicContact CE2-CB 4.05Å; Y126-C137 VanDerWaalsContact CZ-CB 3.45Å; Y126-C137 WeakPolarHBondContact OH-CB 3.3Å; Y126-C137 PolarHBondContact OH-SG 3.28Å; Y126-C137 VanDerWaalsContact OH-SG 3.33Å; T127-C137 CarbonylContact O-C 3.6Å; T127-C137 WeakPolarHBondContact O-CA 3.31Å; T127-C137 VanDerWaalsContact O-CB 3.28Å; T127-C137 WeakPolarHBondContact O-CB 3.19Å; C128-C137 HydrophobicContact CB-CB 4.03Å; C128-C137 WeakPolarHBondContact CB-SG 3.27Å; C128-C137 WeakPolarHBondContact SG-CB 3.26Å; C128-C137 CovalentContact SG-SG 2.04Å; C128-C137 PolarHBondContact SG-SG 3.09Å; C137-E153 HydrophobicContact CB-CB 4.23Å; C137-E153 PolarHBondContact N-O 3.18Å; C137-E153 PolarHBondContact O-N 2.68Å; C137-G155 VanDerWaalsContact SG-CA 3.59Å
138N96.3Very high95.8Very high5 Ų531.4 Ų31.43%0.02716%0.158CC..EExtended strand (participates in β ladder)trans-158.9166.4177.9-147.3-40.8000110.6T127 L147 N148T127-N138 HydrophobicContact CG2-CB 4.46Å; T127-N138 PolarHBondContact N-O 2.77Å; T127-N138 PolarHBondContact O-N 2.94Å; N138-L147 HydrophobicContact CB-CD1 3.78Å; N138-L147 HydrophobicContact CB-CG 4Å; N138-N148 PolarHBondContact ND2-O 3.21Å
139Y95.8Very high95.3Very high61 Ų6136 Ų3624%0.23919%0.188CC..EExtended strand (participates in β ladder)trans-94.7144.8167-59.6-92.3000110Y120 L125 Y126 E153Y120-Y139 HydrophobicContact CD1-CD1 4.01Å; Y120-Y139 AromaticContact CD1-CE1 3.65Å; Y120-Y139 HydrophobicContact CD1-CE1 3.65Å; Y120-Y139 HydrophobicContact CD2-CE1 4.02Å; Y120-Y139 HydrophobicContact CE1-CD1 4.41Å; Y120-Y139 AromaticContact CE1-CE1 3.73Å; Y120-Y139 HydrophobicContact CE1-CE1 3.73Å; Y120-Y139 HydrophobicContact CE2-CE1 4.06Å; Y120-Y139 HydrophobicContact CG-CD1 4.27Å; Y120-Y139 AromaticContact CG-CE1 3.83Å; Y120-Y139 HydrophobicContact CG-CE1 3.83Å; Y120-Y139 AromaticContact CZ-CE1 3.94Å; L125-Y139 VanDerWaalsContact O-CA 3.3Å; L125-Y139 WeakPolarHBondContact O-CA 3.22Å; Y126-Y139 AromaticContact CD2-CD1 3.8Å; Y126-Y139 HydrophobicContact CD2-CD1 3.8Å; Y126-Y139 HydrophobicContact CD2-CD2 4.34Å; Y126-Y139 AromaticContact CD2-CE1 3.5Å; Y126-Y139 HydrophobicContact CD2-CE1 3.5Å; Y126-Y139 VanDerWaalsContact CD2-CE1 3.5Å; Y126-Y139 HydrophobicContact CD2-CE2 4.06Å; Y126-Y139 HydrophobicContact CD2-CG 4.2Å; Y126-Y139 AromaticContact CD2-CZ 3.62Å; Y126-Y139 HydrophobicContact CE2-CE1 4.24Å; Y126-Y139 HydrophobicContact CE2-CE2 4.14Å; Y126-Y139 AromaticContact CE2-CZ 3.88Å; Y126-Y139 HydrophobicContact CG-CE1 4.36Å; Y139-E153 VanDerWaalsContact CE2-OE1 3.24Å; Y139-E153 WeakPolarHBondContact CE2-OE1 3.34Å; Y139-E153 PolarHBondContact OH-OE1 3Å
140I96.9Very high94.7Very high0 Ų040.4 Ų40.40%023%0.225CC..EExtended strand (participates in β ladder)trans-114.7127.4170.8-60.1164.5000107L71 I87 L117 H124 L125 T127 A142 F145 T146 L147L71-I140 HydrophobicContact CD2-CD1 3.9Å; I87-I140 HydrophobicContact CD1-CB 4.39Å; I87-I140 HydrophobicContact CD1-CD1 3.87Å; I87-I140 HydrophobicContact CD1-CG1 3.93Å; I87-I140 HydrophobicContact CD1-CG2 3.57Å; L117-I140 HydrophobicContact CD1-CD1 4Å; H124-I140 CarbonylContact C-O 3.6Å; H124-I140 VanDerWaalsContact CA-O 3.28Å; H124-I140 WeakPolarHBondContact CA-O 3.2Å; L125-I140 HydrophobicContact CB-CB 4.19Å; L125-I140 HydrophobicContact CD1-CB 4.45Å; L125-I140 HydrophobicContact CD1-CG2 4.46Å; L125-I140 PolarHBondContact N-O 3.13Å; L125-I140 PolarHBondContact O-N 2.73Å; T127-I140 HydrophobicContact CG2-CD1 3.7Å; T127-I140 HydrophobicContact CG2-CG1 3.99Å; I140-A142 PolarHBondContact O-N 2.71Å; I140-F145 HydrophobicContact CG2-CD2 3.7Å; I140-F145 HydrophobicContact CG2-CE2 3.97Å; I140-F145 HydrophobicContact CG2-CG 4.3Å; I140-T146 WeakPolarHBondContact CA-O 3.25Å; I140-L147 HydrophobicContact CG1-CB 4.26Å; I140-L147 HydrophobicContact CG1-CD1 4.09Å
141K95.5Very high94.4Very high98 Ų9842.8 Ų42.843%0.42624%0.244SC..EExtended strand (participates in β ladder)trans-68.9126.9169.8-68.4179.3-167.7164.40109.5T123 D144 F145 T146T123-K141 CarbonylContact O-C 3.56Å; T123-K141 WeakPolarHBondContact O-CA 3.49Å; K141-D144 VanDerWaalsContact CB-OD1 3.24Å; K141-D144 WeakPolarHBondContact CB-OD1 3.3Å; K141-D144 WeakPolarHBondContact CD-OD2 3.38Å; K141-D144 IonicContact NZ-OD2 3.92Å; K141-D144 PolarHBondContact NZ-OD2 3.2Å; K141-F145 WeakPolarHBondContact O-CA 3Å; K141-F145 PolarHBondContact O-N 2.9Å; K141-T146 PolarHBondContact N-O 2.9Å
142A92.6Very high94.2Very high19 Ų1944.3 Ų44.316%0.15725%0.254CS..THydrogen-bonded Turntrans-71.7-31.9-174.900000113.4T123 I140T123-A142 PolarHBondContact O-N 3.03Å; I140-A142 PolarHBondContact O-N 2.71Å
143D89.9Confident94.1Very high109 Ų10946.9 Ų46.958%0.58327%0.266SS*.THydrogen-bonded Turntrans-71.8-47.3-173-66.2-50.2000113.3R84R84-D143 PolarHBondContact NE-O 2.78Å; R84-D143 PolarHBondContact NH2-O 3.4Å; R84-D143 VanDerWaalsContact NH2-O 3.14Å
144D91.3Very high93.9Very high69 Ų6950.5 Ų50.537%0.36929%0.285SS..THydrogen-bonded Turntrans-98.5-12.7179.863.123.9000113.4K141 T146K141-D144 VanDerWaalsContact CB-OD1 3.24Å; K141-D144 WeakPolarHBondContact CB-OD1 3.3Å; K141-D144 WeakPolarHBondContact CD-OD2 3.38Å; K141-D144 IonicContact NZ-OD2 3.92Å; K141-D144 PolarHBondContact NZ-OD2 3.2Å; D144-T146 HydrophobicContact CB-CG2 4.19Å; D144-T146 VanDerWaalsContact CG-OG1 3.22Å; D144-T146 VanDerWaalsContact OD1-CB 3.31Å; D144-T146 WeakPolarHBondContact OD1-CB 3.31Å; D144-T146 WeakPolarHBondContact OD1-CG2 3.16Å; D144-T146 PolarHBondContact OD1-N 2.9Å; D144-T146 PolarHBondContact OD1-OG1 3.29Å; D144-T146 PolarHBondContact OD2-OG1 2.8Å
145F96.3Very high93.8Very high6 Ų648.9 Ų48.93%0.02628%0.278CS..THydrogen-bonded Turntrans56.346.2-173.6-156-114.9000113.2Y64 L71 A73 R84 P85 I87 L125 I140 K141Y64-F145 HydrophobicContact CD1-CD2 4.13Å; Y64-F145 AromaticContact CD1-CE2 3.4Å; Y64-F145 HydrophobicContact CD1-CE2 3.4Å; Y64-F145 HydrophobicContact CD1-CZ 4.03Å; Y64-F145 AromaticContact CE1-CD2 3.82Å; Y64-F145 HydrophobicContact CE1-CD2 3.82Å; Y64-F145 AromaticContact CE1-CE2 3.57Å; Y64-F145 HydrophobicContact CE1-CE2 3.57Å; Y64-F145 HydrophobicContact CG-CE2 4.49Å; L71-F145 HydrophobicContact CB-CE1 4.26Å; L71-F145 HydrophobicContact CB-CZ 4.05Å; A73-F145 HydrophobicContact CB-CD1 4.1Å; A73-F145 HydrophobicContact CB-CD2 4.12Å; A73-F145 HydrophobicContact CB-CE1 4.07Å; A73-F145 HydrophobicContact CB-CE2 4.11Å; A73-F145 HydrophobicContact CB-CG 4.12Å; A73-F145 HydrophobicContact CB-CZ 4.08Å; R84-F145 HydrophobicContact CB-CB 3.63Å; R84-F145 HydrophobicContact CB-CD1 4.33Å; R84-F145 HydrophobicContact CB-CG 4.23Å; R84-F145 HydrophobicContact CG-CB 3.83Å; P85-F145 WeakPolarHBondContact O-CD1 3.18Å; I87-F145 HydrophobicContact CD1-CD1 3.65Å; I87-F145 HydrophobicContact CD1-CD2 4.29Å; I87-F145 HydrophobicContact CD1-CE1 3.6Å; I87-F145 HydrophobicContact CD1-CE2 4.23Å; I87-F145 HydrophobicContact CD1-CG 4.01Å; I87-F145 HydrophobicContact CD1-CZ 3.91Å; I87-F145 VanDerWaalsContact CD1-O 3.27Å; I87-F145 WeakPolarHBondContact CD1-O 3.13Å; I87-F145 HydrophobicContact CG1-CD1 3.66Å; I87-F145 HydrophobicContact CG1-CE1 3.71Å; I87-F145 HydrophobicContact CG1-CG 4.4Å; I87-F145 HydrophobicContact CG1-CZ 4.49Å; I87-F145 WeakPolarHBondContact CG1-O 3.34Å; L125-F145 HydrophobicContact CD1-CE2 3.98Å; I140-F145 HydrophobicContact CG2-CD2 3.7Å; I140-F145 HydrophobicContact CG2-CE2 3.97Å; I140-F145 HydrophobicContact CG2-CG 4.3Å; K141-F145 WeakPolarHBondContact O-CA 3Å; K141-F145 PolarHBondContact O-N 2.9Å
146T95.8Very high93.7Very high61 Ų6153.2 Ų53.237%0.37430%0.297SS..EExtended strand (participates in β ladder)trans-106.8147.7175.9640000113.4I140 K141 D144I140-T146 WeakPolarHBondContact CA-O 3.25Å; K141-T146 PolarHBondContact N-O 2.9Å; D144-T146 HydrophobicContact CB-CG2 4.19Å; D144-T146 VanDerWaalsContact CG-OG1 3.22Å; D144-T146 VanDerWaalsContact OD1-CB 3.31Å; D144-T146 WeakPolarHBondContact OD1-CB 3.31Å; D144-T146 WeakPolarHBondContact OD1-CG2 3.16Å; D144-T146 PolarHBondContact OD1-N 2.9Å; D144-T146 PolarHBondContact OD1-OG1 3.29Å; D144-T146 PolarHBondContact OD2-OG1 2.8Å
147L94.8Very high93.5Very high27 Ų2750.9 Ų50.914%0.14129%0.287CS..EExtended strand (participates in β ladder)trans-121141176.4176.4149.8000108.9I87 W89 T127 N138 I140 P149I87-L147 HydrophobicContact CD1-CB 4.28Å; I87-L147 HydrophobicContact CG2-CB 3.89Å; I87-L147 HydrophobicContact CG2-CD1 4.35Å; W89-L147 HydrophobicContact CD2-CD1 4.06Å; W89-L147 HydrophobicContact CE3-CD1 4.09Å; W89-L147 HydrophobicContact CG-CD1 4.43Å; T127-L147 HydrophobicContact CG2-CD1 4.08Å; N138-L147 HydrophobicContact CB-CD1 3.78Å; N138-L147 HydrophobicContact CB-CG 4Å; I140-L147 HydrophobicContact CG1-CB 4.26Å; I140-L147 HydrophobicContact CG1-CD1 4.09Å; L147-P149 VanDerWaalsContact O-CD 3.29Å; L147-P149 WeakPolarHBondContact O-CD 3.37Å
148N92.6Very high93.4Very high90 Ų9051.2 Ų51.248%0.48129%0.288SS..  trans-96.5103.5178.6179.42.6000111.2N138 A150 A151N138-N148 PolarHBondContact ND2-O 3.21Å; N148-A150 PolarHBondContact O-N 2.83Å; N148-A150 VanDerWaalsContact O-N 3.11Å; N148-A150 WeakPolarHBondContact OD1-CB 3.4Å; N148-A150 PolarHBondContact OD1-N 3.34Å; N148-A150 VanDerWaalsContact OD1-N 3.07Å; N148-A151 HydrophobicContact CB-CB 4.13Å; N148-A151 PolarHBondContact O-N 3Å
149P86.3Confident93.4Very high96 Ų9651 Ų5162%0.62329%0.287SS*.THydrogen-bonded Turntrans-67.3-13.6-17629-36.5000114.2L147 L152L147-P149 VanDerWaalsContact O-CD 3.29Å; L147-P149 WeakPolarHBondContact O-CD 3.37Å; P149-L152 WeakPolarHBondContact O-CD1 3.23Å; P149-L152 WeakPolarHBondContact O-CG 3.43Å
150A86.1Confident93.4Very high94 Ų9448 Ų4878%0.77728%0.275SS*.THydrogen-bonded Turntrans-83.8-14.1173.900000113.5N148N148-A150 PolarHBondContact O-N 2.83Å; N148-A150 VanDerWaalsContact O-N 3.11Å; N148-A150 WeakPolarHBondContact OD1-CB 3.4Å; N148-A150 PolarHBondContact OD1-N 3.34Å; N148-A150 VanDerWaalsContact OD1-N 3.07Å
151A90.9Very high93.4Very high50 Ų5049.8 Ų49.841%0.41328%0.282SS..  trans-107.543.2-175.600000112.6N148 E153N148-A151 HydrophobicContact CB-CB 4.13Å; N148-A151 PolarHBondContact O-N 3Å; A151-E153 PolarHBondContact O-N 3.27Å
152L93.8Very high93.4Very high59 Ų5946.1 Ų46.131%0.30927%0.267SS..  trans-74.7115.7-178.8-69166.8000111.4W89 K136 P149W89-L152 HydrophobicContact CZ2-CD2 3.62Å; K136-L152 HydrophobicContact CB-CD2 4.27Å; P149-L152 WeakPolarHBondContact O-CD1 3.23Å; P149-L152 WeakPolarHBondContact O-CG 3.43Å
153E94.8Very high93.6Very high54 Ų5446.1 Ų46.125%0.25227%0.266SS..EExtended strand (participates in β ladder)trans-75.9152.5168-74.5-167.2-159.700111.1Y126 K136 C137 Y139 A151 K158 L195Y126-E153 PolarHBondContact OH-OE2 3.02Å; K136-E153 WeakPolarHBondContact CA-O 3.42Å; K136-E153 WeakPolarHBondContact CD-O 3.24Å; C137-E153 HydrophobicContact CB-CB 4.23Å; C137-E153 PolarHBondContact N-O 3.18Å; C137-E153 PolarHBondContact O-N 2.68Å; Y139-E153 VanDerWaalsContact CE2-OE1 3.24Å; Y139-E153 WeakPolarHBondContact CE2-OE1 3.34Å; Y139-E153 PolarHBondContact OH-OE1 3Å; A151-E153 PolarHBondContact O-N 3.27Å; E153-K158 IonicContact OE2-NZ 3.17Å; E153-K158 PolarHBondContact OE2-NZ 3.44Å; E153-L195 WeakPolarHBondContact OE2-CD2 3.38Å
154D94Very high93.8Very high79 Ų7945.2 Ų45.242%0.42227%0.273SS..EExtended strand (participates in β ladder)trans-69.4136.5167.7-166.957.5000112K136 K156 K158K136-D154 IonicContact NZ-OD1 2.7Å; K136-D154 PolarHBondContact NZ-OD1 2.64Å; D154-K156 WeakPolarHBondContact OD2-CB 3.32Å; D154-K156 PolarHBondContact OD2-N 2.9Å; D154-K158 WeakPolarHBondContact O-CE 3.35Å; D154-K158 PolarHBondContact O-NZ 3.05Å
155G95.2Very high94Very high0 Ų046 Ų460%027%0.273CS..  trans-102.12.3-176.800000114.7P135 C137 G157 K158 C159P135-G155 VanDerWaalsContact O-CA 3.26Å; P135-G155 WeakPolarHBondContact O-CA 3.29Å; P135-G155 PolarHBondContact O-N 3.48Å; C137-G155 VanDerWaalsContact SG-CA 3.59Å; G155-G157 PolarHBondContact O-N 3.09Å; G155-K158 WeakPolarHBondContact O-CA 3.26Å; G155-K158 WeakPolarHBondContact O-CB 3.33Å; G155-K158 PolarHBondContact O-N 2.02Å; G155-C159 PolarHBondContact O-N 2.81Å
156K95.1Very high93.8Very high91 Ų9146.3 Ų46.340%0.39628%0.278SS..BIsolated β-bridgetrans-56.5123.9-178.8-170.5176.3-174.1179.50111.1D154 K158 Y161 N182D154-K156 WeakPolarHBondContact OD2-CB 3.32Å; D154-K156 PolarHBondContact OD2-N 2.9Å; K156-K158 PolarHBondContact O-N 2.88Å; K156-K158 VanDerWaalsContact O-N 3.13Å; K156-Y161 HydrophobicContact CG-CE2 4.31Å; K156-N182 WeakPolarHBondContact CE-O 3.27Å; K156-N182 VanDerWaalsContact CG-O 3.3Å; K156-N182 WeakPolarHBondContact CG-O 3.36Å
157G93.4Very high93.9Very high0 Ų044.6 Ų44.60%027%0.266CS..THydrogen-bonded Turntrans72.3-7.7-175.500000115.7G155 S178 T180 L192G155-G157 PolarHBondContact O-N 3.09Å; G157-S178 PolarHBondContact O-OG 3.04Å; G157-T180 WeakPolarHBondContact O-CG2 2.87Å; G157-L192 WeakPolarHBondContact O-CD2 3.48Å
158K94.9Very high94Very high7 Ų744.2 Ų44.23%0.0326%0.264CS..THydrogen-bonded Turntrans-91.2-32.2170.7-53.8-178.3-173.91580112Y126 E153 D154 G155 K156 H167 L176 L192 N194Y126-K158 WeakPolarHBondContact OH-CD 3.48Å; Y126-K158 PolarHBondContact OH-NZ 2.85Å; Y126-K158 VanDerWaalsContact OH-NZ 3.07Å; E153-K158 IonicContact OE2-NZ 3.17Å; E153-K158 PolarHBondContact OE2-NZ 3.44Å; D154-K158 WeakPolarHBondContact O-CE 3.35Å; D154-K158 PolarHBondContact O-NZ 3.05Å; G155-K158 WeakPolarHBondContact O-CA 3.26Å; G155-K158 WeakPolarHBondContact O-CB 3.33Å; G155-K158 PolarHBondContact O-N 2.02Å; K156-K158 PolarHBondContact O-N 2.88Å; K156-K158 VanDerWaalsContact O-N 3.13Å; K158-H167 PolarHBondContact O-NE2 3.01Å; K158-L176 HydrophobicContact CB-CD2 3.93Å; K158-L176 HydrophobicContact CD-CD2 4.18Å; K158-L176 HydrophobicContact CG-CD2 4.09Å; K158-L192 HydrophobicContact CG-CD2 4.38Å; K158-N194 VanDerWaalsContact CE-ND2 3.27Å; K158-N194 WeakPolarHBondContact CE-ND2 3.5Å
159C94.8Very high94.2Very high0 Ų040.7 Ų40.70%025%0.25CC..BIsolated β-bridgetrans-143.6145.1-174.9174.60000109.6C128 P135 G155C128-C159 HydrophobicContact CB-CB 3.6Å; P135-C159 HydrophobicContact CB-CB 4.07Å; G155-C159 PolarHBondContact O-N 2.81Å
160P96.4Very high94.7Very high0 Ų037.1 Ų37.10%023%0.225CC..  trans-69.5152.5178.129.5-36.5000111.2R115 T130 P135 H167 T180R115-P160 HydrophobicContact CB-CG 4.38Å; R115-P160 HydrophobicContact CG-CG 4.02Å; T130-P160 WeakPolarHBondContact CG2-O 3.12Å; P135-P160 VanDerWaalsContact CG-O 3.29Å; P135-P160 WeakPolarHBondContact CG-O 3.42Å; P160-H167 VanDerWaalsContact CD-CD2 3.46Å; P160-H167 WeakPolarHBondContact CD-CD2 3.45Å; P160-H167 HydrophobicContact CG-CB 3.89Å; P160-T180 WeakPolarHBondContact CA-OG1 3.44Å; P160-T180 WeakPolarHBondContact CB-OG1 3.21Å
161Y97.1Very high95.1Very high36 Ų3633.5 Ų33.514%0.14119%0.193CC..SBendtrans-68.9-42.6168.1-76.5-105.8000111.6F133 P135 K156 N182 N183 F184F133-Y161 WeakPolarHBondContact CA-O 3.38Å; F133-Y161 WeakPolarHBondContact CG-O 3.38Å; F133-Y161 WeakPolarHBondContact O-CD1 3.39Å; P135-Y161 VanDerWaalsContact CD-CD1 3.49Å; P135-Y161 VanDerWaalsContact CD-CE1 3.5Å; P135-Y161 HydrophobicContact CG-CD1 4.19Å; P135-Y161 HydrophobicContact CG-CD2 3.85Å; P135-Y161 HydrophobicContact CG-CE1 4.42Å; P135-Y161 HydrophobicContact CG-CE2 4.11Å; P135-Y161 HydrophobicContact CG-CG 3.87Å; K156-Y161 HydrophobicContact CG-CE2 4.31Å; Y161-N182 WeakPolarHBondContact CE2-O 3.36Å; Y161-N183 VanDerWaalsContact CD2-C 3.5Å; Y161-N183 WeakPolarHBondContact CD2-O 3.32Å; Y161-F184 HydrophobicContact CD1-CB 4.05Å; Y161-F184 HydrophobicContact CD1-CD2 4.36Å; Y161-F184 HydrophobicContact CE1-CB 4.38Å
162D96.3Very high95.3Very high22 Ų2231.4 Ų31.412%0.11818%0.175CC..SBendtrans-101.2125.9-172.5-169.6-51.7000110.9K104 F133 A164 K165K104-D162 IonicContact NZ-OD2 3.7Å; K104-D162 PolarHBondContact NZ-OD2 3.38Å; F133-D162 HydrophobicContact CD1-CB 4.45Å; F133-D162 HydrophobicContact CE1-CB 3.47Å; F133-D162 VanDerWaalsContact CE1-CB 3.47Å; F133-D162 WeakPolarHBondContact CE1-OD2 3.3Å; F133-D162 VanDerWaalsContact CZ-CA 3.48Å; F133-D162 HydrophobicContact CZ-CB 3.64Å; F133-D162 VanDerWaalsContact CZ-CG 3.45Å; F133-D162 WeakPolarHBondContact CZ-OD2 3.43Å; D162-A164 PolarHBondContact O-N 2.84Å; D162-A164 WeakPolarHBondContact OD1-CB 3.29Å; D162-A164 PolarHBondContact OD1-N 3.12Å; D162-K165 HydrophobicContact CB-CB 4.36Å; D162-K165 HydrophobicContact CB-CG 3.69Å; D162-K165 PolarHBondContact O-N 3.27Å
163P95.6Very high95.2Very high19 Ų1933.6 Ų33.612%0.12319%0.187CC..THydrogen-bonded Turntrans-67.5-17.6-176.928.3-35000113.8Y113 R115 T130Y113-P163 HydrophobicContact CD1-CB 4.29Å; Y113-P163 HydrophobicContact CD2-CB 3.63Å; Y113-P163 HydrophobicContact CD2-CG 3.92Å; Y113-P163 HydrophobicContact CE2-CB 4.14Å; Y113-P163 HydrophobicContact CE2-CG 4.08Å; Y113-P163 HydrophobicContact CG-CB 3.72Å; R115-P163 PolarHBondContact NH1-O 2.92Å; R115-P163 PolarHBondContact NH2-O 3.06Å; R115-P163 VanDerWaalsContact NH2-O 3.08Å; T130-P163 HydrophobicContact CG2-CB 4.14Å
164A94.2Very high95Very high89 Ų8936.3 Ų36.374%0.73620%0.198SC*.THydrogen-bonded Turntrans-86.5-11.4178.200000113.5D162D162-A164 PolarHBondContact O-N 2.84Å; D162-A164 WeakPolarHBondContact OD1-CB 3.29Å; D162-A164 PolarHBondContact OD1-N 3.12Å
165K94.7Very high95Very high86 Ų8634 Ų3437%0.37418%0.184SC..SBendtrans-85.7145.6-176.2-65.9-70.7-172.31690112.9R115 D162 L181R115-K165 PolarHBondContact NH2-O 3.33Å; D162-K165 HydrophobicContact CB-CB 4.36Å; D162-K165 HydrophobicContact CB-CG 3.69Å; D162-K165 PolarHBondContact O-N 3.27Å; K165-L181 HydrophobicContact CB-CD1 3.87Å; K165-L181 HydrophobicContact CD-CD1 3.72Å; K165-L181 HydrophobicContact CG-CD1 3.77Å
166G93.8Very high95.1Very high12 Ų1234 Ų3412%0.12418%0.184CC..  trans-56.3141173.100000113.2D215 F216G166-D215 WeakPolarHBondContact CA-OD1 3.35Å; G166-D215 PolarHBondContact N-OD1 2.87Å; G166-F216 CarbonylContact C-O 3.53Å; G166-F216 VanDerWaalsContact CA-O 3.24Å; G166-F216 WeakPolarHBondContact CA-O 3.31Å
167H96.4Very high95.2Very high26 Ų2629.6 Ų29.612%0.1217%0.165CC..  trans-156.2147.9-179.6161.9-92000108.7R115 K158 P160 A179 F216R115-H167 PolarHBondContact O-CE1 3.46Å; R115-H167 VanDerWaalsContact O-CE1 3.27Å; R115-H167 PolarHBondContact O-ND1 3.14Å; K158-H167 PolarHBondContact O-NE2 3.01Å; P160-H167 VanDerWaalsContact CD-CD2 3.46Å; P160-H167 WeakPolarHBondContact CD-CD2 3.45Å; P160-H167 HydrophobicContact CG-CB 3.89Å; H167-A179 WeakPolarHBondContact CA-O 3.38Å; H167-F216 PolarHBondContact N-O 3.39Å; H167-F216 VanDerWaalsContact N-O 3.13Å
168T97.8Very high95.4Very high18 Ų1829.6 Ų29.611%0.1117%0.165CC..EExtended strand (participates in β ladder)trans-154.3162.9166.5-164.50000110.4S178 A179 F216 G218 S219 F238T168-S178 WeakPolarHBondContact O-CA 3.49Å; T168-A179 HydrophobicContact CG2-CB 4Å; T168-A179 PolarHBondContact N-O 3.33Å; T168-A179 VanDerWaalsContact N-O 3.12Å; T168-A179 PolarHBondContact O-N 3.36Å; T168-F216 HydrophobicContact CG2-CB 4.49Å; T168-G218 VanDerWaalsContact OG1-C 3.28Å; T168-G218 VanDerWaalsContact OG1-CA 3.26Å; T168-G218 WeakPolarHBondContact OG1-CA 3.29Å; T168-S219 PolarHBondContact OG1-N 3.21Å; T168-S219 VanDerWaalsContact OG1-N 3.16Å; T168-S219 PolarHBondContact OG1-OG 3.21Å; T168-S219 VanDerWaalsContact OG1-OG 3.05Å; T168-F238 HydrophobicContact CG2-CD1 4.36Å
169G96.2Very high95.6Very high17 Ų1729.3 Ų29.318%0.17516%0.164CC..EExtended strand (participates in β ladder)trans-178.5170.1171.100000112.3Y177 S219G169-Y177 CarbonylContact C-O 3.58Å; G169-Y177 WeakPolarHBondContact CA-O 3.41Å; G169-S219 WeakPolarHBondContact CA-OG 3.46Å; G169-S219 PolarHBondContact N-OG 2.89Å
170L96.5Very high95.7Very high21 Ų2129.3 Ų29.311%0.1116%0.164CC..EExtended strand (participates in β ladder)trans-152.5149.4172.362.8158.7000110.8V172 Y177 S219 L221 I236L170-V172 HydrophobicContact CD1-CG2 3.58Å; L170-V172 HydrophobicContact CG-CG2 4.03Å; L170-Y177 PolarHBondContact N-O 3.18Å; L170-Y177 PolarHBondContact O-N 3.41Å; L170-S219 VanDerWaalsContact CD2-OG 3.23Å; L170-S219 WeakPolarHBondContact CD2-OG 3.31Å; L170-L221 HydrophobicContact CD1-CB 3.77Å; L170-I236 HydrophobicContact CD2-CG2 4Å
171I95.8Very high95.7Very high18 Ų1829.8 Ų29.89%0.09217%0.167CC..EExtended strand (participates in β ladder)trans-87.9129.2167.9-68.2161.7000109.2F116 Q118 Y120 Y126 E175 L176F116-I171 HydrophobicContact CE1-CD1 3.81Å; F116-I171 HydrophobicContact CE1-CG1 4.3Å; F116-I171 HydrophobicContact CZ-CD1 3.98Å; F116-I171 HydrophobicContact CZ-CG1 4.01Å; Q118-I171 HydrophobicContact CB-CD1 4.35Å; Y120-I171 HydrophobicContact CD2-CD1 4.1Å; Y120-I171 HydrophobicContact CD2-CG2 4.28Å; Y126-I171 HydrophobicContact CD1-CD1 4.29Å; Y126-I171 HydrophobicContact CG-CD1 4.39Å; I171-E175 CarbonylContact C-O 3.47Å; I171-E175 WeakPolarHBondContact CA-O 3.43Å; I171-L176 HydrophobicContact CG1-CB 4.19Å; I171-L176 HydrophobicContact CG1-CD1 4.07Å
172V94.3Very high95.5Very high6 Ų629.9 Ų29.94%0.03617%0.169CC..EExtended strand (participates in β ladder)trans-132.4127.6172.9-177.80000107.5L170 K174 E175 Y177 L221 I236 K263L170-V172 HydrophobicContact CD1-CG2 3.58Å; L170-V172 HydrophobicContact CG-CG2 4.03Å; V172-K174 PolarHBondContact O-N 2.98Å; V172-E175 PolarHBondContact N-O 3.35Å; V172-E175 PolarHBondContact O-N 3.28Å; V172-E175 VanDerWaalsContact O-O 3.14Å; V172-Y177 HydrophobicContact CB-CD2 4.25Å; V172-Y177 HydrophobicContact CB-CE2 4.09Å; V172-Y177 HydrophobicContact CG2-CD2 4.42Å; V172-L221 HydrophobicContact CG1-CD1 4.32Å; V172-L221 HydrophobicContact CG1-CD2 3.94Å; V172-L221 HydrophobicContact CG2-CB 4.23Å; V172-L221 HydrophobicContact CG2-CD2 4.07Å; V172-I236 HydrophobicContact CG2-CD1 3.89Å; V172-K263 HydrophobicContact CG1-CD 3.76Å
173D91.8Very high95.4Very high105 Ų10529.9 Ų29.956%0.56117%0.169SC*.THydrogen-bonded Turntrans51.831.5176.7-53.9-21.1000114.4E175 K263D173-E175 VanDerWaalsContact C-N 3.33Å; D173-K263 WeakPolarHBondContact OD2-CD 3.16Å; D173-K263 WeakPolarHBondContact OD2-CE 3.42Å; D173-K263 IonicContact OD2-NZ 3.72Å; D173-K263 PolarHBondContact OD2-NZ 3.5Å
174K91.8Very high95.2Very high111 Ų11131.5 Ų31.548%0.48317%0.174SC..THydrogen-bonded Turntrans72.49.3-174.6-53175.7-173.4171.10116.3Y120 V172 G196Y120-K174 HydrophobicContact CE2-CB 3.8Å; Y120-K174 HydrophobicContact CE2-CG 4.38Å; Y120-K174 WeakPolarHBondContact CE2-O 3.31Å; V172-K174 PolarHBondContact O-N 2.98Å; K174-G196 PolarHBondContact O-N 3.17Å
175E93.8Very high95.1Very high29 Ų2933.6 Ų33.614%0.13617%0.173CC..EExtended strand (participates in β ladder)trans-98.5132167.1-55.1-172.611300109.7I171 V172 D173 Y177 R193I171-E175 CarbonylContact C-O 3.47Å; I171-E175 WeakPolarHBondContact CA-O 3.43Å; V172-E175 PolarHBondContact N-O 3.35Å; V172-E175 PolarHBondContact O-N 3.28Å; V172-E175 VanDerWaalsContact O-O 3.14Å; D173-E175 VanDerWaalsContact C-N 3.33Å; E175-Y177 HydrophobicContact CB-CD2 4.49Å; E175-Y177 HydrophobicContact CB-CE2 3.94Å; E175-Y177 PolarHBondContact OE2-OH 3.43Å; E175-R193 HydrophobicContact CB-CG 3.91Å; E175-R193 WeakPolarHBondContact OE1-CD 3.38Å; E175-R193 IonicContact OE1-CZ 3.23Å; E175-R193 IonicContact OE1-NE 3.82Å; E175-R193 PolarHBondContact OE1-NE 2.63Å; E175-R193 IonicContact OE1-NH2 2.81Å; E175-R193 WeakPolarHBondContact OE2-CD 3.4Å; E175-R193 IonicContact OE2-CZ 3.05Å; E175-R193 IonicContact OE2-NE 3.52Å; E175-R193 PolarHBondContact OE2-NE 2.54Å
176L95.9Very high95Very high0 Ų030.3 Ų30.30%016%0.163CC..EExtended strand (participates in β ladder)trans-85.3117.6170.917264000109.5F116 Y126 K158 I171 R193 N194 L195F116-L176 HydrophobicContact CD2-CD1 4.42Å; F116-L176 HydrophobicContact CE1-CD1 4.18Å; F116-L176 HydrophobicContact CE2-CD1 3.81Å; F116-L176 HydrophobicContact CZ-CD1 3.67Å; Y126-L176 HydrophobicContact CE1-CD2 3.85Å; K158-L176 HydrophobicContact CB-CD2 3.93Å; K158-L176 HydrophobicContact CD-CD2 4.18Å; K158-L176 HydrophobicContact CG-CD2 4.09Å; I171-L176 HydrophobicContact CG1-CB 4.19Å; I171-L176 HydrophobicContact CG1-CD1 4.07Å; L176-R193 WeakPolarHBondContact O-CA 3.28Å; L176-N194 WeakPolarHBondContact CA-O 3.22Å; L176-N194 PolarHBondContact N-O 3.08Å; L176-N194 PolarHBondContact O-N 2.89Å; L176-L195 HydrophobicContact CB-CD1 3.81Å; L176-L195 HydrophobicContact CB-CG 4.03Å
177Y97.8Very high94.9Very high0 Ų033.6 Ų33.60%018%0.181CC..EExtended strand (participates in β ladder)trans-94.2122.7165.7-67.9-101.4000108.1G169 L170 V172 E175 L192 R193 I236 V261 K263 W276G169-Y177 CarbonylContact C-O 3.58Å; G169-Y177 WeakPolarHBondContact CA-O 3.41Å; L170-Y177 PolarHBondContact N-O 3.18Å; L170-Y177 PolarHBondContact O-N 3.41Å; V172-Y177 HydrophobicContact CB-CD2 4.25Å; V172-Y177 HydrophobicContact CB-CE2 4.09Å; V172-Y177 HydrophobicContact CG2-CD2 4.42Å; E175-Y177 HydrophobicContact CB-CD2 4.49Å; E175-Y177 HydrophobicContact CB-CE2 3.94Å; E175-Y177 PolarHBondContact OE2-OH 3.43Å; Y177-L192 CarbonylContact C-O 3.45Å; Y177-L192 WeakPolarHBondContact CA-O 3.23Å; Y177-R193 HydrophobicContact CD1-CB 4.19Å; Y177-R193 HydrophobicContact CD1-CG 4.37Å; Y177-R193 HydrophobicContact CD2-CG 4.48Å; Y177-R193 HydrophobicContact CE1-CB 4.18Å; Y177-R193 HydrophobicContact CE1-CG 4.11Å; Y177-R193 HydrophobicContact CE2-CG 4.19Å; Y177-R193 WeakPolarHBondContact OH-CD 3.11Å; Y177-R193 PolarHBondContact OH-NH1 2.87Å; Y177-I236 HydrophobicContact CD1-CB 4.11Å; Y177-I236 HydrophobicContact CD1-CG1 3.68Å; Y177-I236 HydrophobicContact CD1-CG2 4.1Å; Y177-I236 HydrophobicContact CD2-CG1 4.33Å; Y177-I236 HydrophobicContact CE1-CB 4.43Å; Y177-I236 HydrophobicContact CE1-CG1 3.65Å; Y177-I236 HydrophobicContact CE2-CG1 4.35Å; Y177-I236 HydrophobicContact CG-CG1 4.02Å; Y177-I236 HydrophobicContact CG-CG2 4.18Å; Y177-V261 HydrophobicContact CE1-CG2 4.4Å; Y177-K263 WeakPolarHBondContact OH-CG 3.1Å; Y177-K263 PolarHBondContact OH-O 3.41Å; Y177-W276 HydrophobicContact CD1-CH2 4.22Å; Y177-W276 AromaticContact CE1-CH2 3.84Å; Y177-W276 HydrophobicContact CE1-CH2 3.84Å
178S97.8Very high94.9Very high0 Ų035.4 Ų35.40%019%0.189CC..EExtended strand (participates in β ladder)trans-137.6148.5-175.856.60000112.2G157 T168 I191 L192G157-S178 PolarHBondContact O-OG 3.04Å; T168-S178 WeakPolarHBondContact O-CA 3.49Å; S178-I191 WeakPolarHBondContact O-CA 3.5Å; S178-L192 PolarHBondContact N-O 3.07Å; S178-L192 PolarHBondContact O-N 2.88Å
179A98.3Very high94.8Very high0 Ų035.1 Ų35.10%019%0.188CC..EExtended strand (participates in β ladder)trans-134116.6176.600000110.2H167 T168 V190 I191 F216 F238H167-A179 WeakPolarHBondContact CA-O 3.38Å; T168-A179 HydrophobicContact CG2-CB 4Å; T168-A179 PolarHBondContact N-O 3.33Å; T168-A179 VanDerWaalsContact N-O 3.12Å; T168-A179 PolarHBondContact O-N 3.36Å; A179-V190 WeakPolarHBondContact CA-O 3.36Å; A179-I191 HydrophobicContact CB-CG1 3.81Å; A179-F216 HydrophobicContact CB-CD1 3.56Å; A179-F216 HydrophobicContact CB-CE1 3.75Å; A179-F216 HydrophobicContact CB-CG 3.96Å; A179-F216 HydrophobicContact CB-CZ 4.28Å; A179-F238 HydrophobicContact CB-CD1 3.67Å; A179-F238 HydrophobicContact CB-CE1 3.92Å
180T97.4Very high94.9Very high0 Ų034.8 Ų34.80%018%0.182CC..EExtended strand (participates in β ladder)trans-166.2-171-170.9-157.20000112.7G157 P160 V190 F216G157-T180 WeakPolarHBondContact O-CG2 2.87Å; P160-T180 WeakPolarHBondContact CA-OG1 3.44Å; P160-T180 WeakPolarHBondContact CB-OG1 3.21Å; T180-V190 PolarHBondContact N-O 3.11Å; T180-V190 PolarHBondContact O-N 3.06Å; T180-F216 WeakPolarHBondContact O-CE2 3.36Å
181L95.8Very high95Very high11 Ų1133.8 Ų33.86%0.05818%0.177CC..EExtended strand (participates in β ladder)trans-101.2125.5177.8-55.1168.4000110K165 N183 E188 P189K165-L181 HydrophobicContact CB-CD1 3.87Å; K165-L181 HydrophobicContact CD-CD1 3.72Å; K165-L181 HydrophobicContact CG-CD1 3.77Å; L181-N183 PolarHBondContact O-N 3.28Å; L181-E188 CarbonylContact C-O 3.17Å; L181-E188 WeakPolarHBondContact CA-O 3.42Å; L181-P189 HydrophobicContact CD2-CB 4.16Å
182N93.6Very high95Very high38 Ų3833.4 Ų33.420%0.20318%0.175CC..  trans-83.6-6.6-167.2-172.367.7000114.1K156 Y161 E188 V190K156-N182 WeakPolarHBondContact CE-O 3.27Å; K156-N182 VanDerWaalsContact CG-O 3.3Å; K156-N182 WeakPolarHBondContact CG-O 3.36Å; Y161-N182 WeakPolarHBondContact CE2-O 3.36Å; N182-E188 HydrophobicContact CB-CB 3.82Å; N182-E188 WeakPolarHBondContact CB-O 3.48Å; N182-E188 PolarHBondContact N-O 3.07Å; N182-E188 PolarHBondContact ND2-OE2 3.1Å; N182-V190 HydrophobicContact CB-CB 4.31Å; N182-V190 HydrophobicContact CB-CG1 3.91Å
183N93.6Very high95.1Very high21 Ų2133.4 Ų33.411%0.11218%0.175CC..SBendtrans-138.2165.3-174.5712.3000113.4Y161 L181 L185 G186 T187 E188Y161-N183 VanDerWaalsContact CD2-C 3.5Å; Y161-N183 WeakPolarHBondContact CD2-O 3.32Å; L181-N183 PolarHBondContact O-N 3.28Å; N183-L185 VanDerWaalsContact C-N 3.29Å; N183-L185 PolarHBondContact O-N 3.36Å; N183-G186 PolarHBondContact O-N 3.09Å; N183-G186 VanDerWaalsContact O-N 3.17Å; N183-G186 PolarHBondContact OD1-N 2.95Å; N183-T187 PolarHBondContact ND2-OG1 3.16Å; N183-T187 PolarHBondContact OD1-N 3.21Å; N183-E188 HydrophobicContact CB-CB 4.38Å; N183-E188 HydrophobicContact CB-CG 4.41Å; N183-E188 WeakPolarHBondContact CB-OE1 3.22Å; N183-E188 VanDerWaalsContact ND2-CD 3.3Å; N183-E188 VanDerWaalsContact ND2-CG 3.33Å; N183-E188 WeakPolarHBondContact ND2-CG 3.35Å; N183-E188 PolarHBondContact ND2-OE1 3.43Å; N183-E188 PolarHBondContact OD1-N 2.9Å
184F92.9Very high95Very high53 Ų5330.9 Ų30.923%0.23216%0.161CC..THydrogen-bonded Turntrans-58.9-35.8-177.7179.1-86000113.5K102 K104 F133 Y161 G186K102-F184 HydrophobicContact CB-CE1 4.15Å; K102-F184 HydrophobicContact CB-CE2 4.15Å; K102-F184 HydrophobicContact CB-CZ 3.51Å; K102-F184 HydrophobicContact CD-CD2 4.36Å; K102-F184 HydrophobicContact CD-CE2 3.79Å; K102-F184 HydrophobicContact CD-CZ 3.94Å; K102-F184 HydrophobicContact CG-CZ 4.33Å; K104-F184 HydrophobicContact CG-CZ 4Å; F133-F184 HydrophobicContact CB-CD2 3.76Å; F133-F184 HydrophobicContact CB-CE2 3.52Å; F133-F184 AromaticContact CD1-CD2 3.92Å; F133-F184 HydrophobicContact CD1-CD2 3.92Å; F133-F184 AromaticContact CD1-CE2 3.7Å; F133-F184 HydrophobicContact CD1-CE2 3.7Å; F133-F184 HydrophobicContact CD1-CZ 4.2Å; F133-F184 HydrophobicContact CG-CD2 4.29Å; F133-F184 AromaticContact CG-CE2 3.89Å; F133-F184 HydrophobicContact CG-CE2 3.89Å; Y161-F184 HydrophobicContact CD1-CB 4.05Å; Y161-F184 HydrophobicContact CD1-CD2 4.36Å; Y161-F184 HydrophobicContact CE1-CB 4.38Å; F184-G186 VanDerWaalsContact C-N 3.3Å; F184-G186 PolarHBondContact O-N 2.67Å
185L92.2Very high94.4Very high134 Ų13426.6 Ų26.670%0.70214%0.143SC*.THydrogen-bonded Turntrans-76.2-16.5-178.7-62.4176000113.3N183 T187N183-L185 VanDerWaalsContact C-N 3.29Å; N183-L185 PolarHBondContact O-N 3.36Å; L185-T187 HydrophobicContact CB-CG2 4.05Å
186G90.7Very high93.3Very high16 Ų1626.4 Ų26.417%0.16515%0.149CC..SBendtrans72.731-175.200000114N183 F184N183-G186 PolarHBondContact O-N 3.09Å; N183-G186 VanDerWaalsContact O-N 3.17Å; N183-G186 PolarHBondContact OD1-N 2.95Å; F184-G186 VanDerWaalsContact C-N 3.3Å; F184-G186 PolarHBondContact O-N 2.67Å
187T92.8Very high91.5Very high82 Ų8235.3 Ų35.350%0.50319%0.191SC..  trans-109.5-15.2-17655.50000114.4N183 L185 P189N183-T187 PolarHBondContact ND2-OG1 3.16Å; N183-T187 PolarHBondContact OD1-N 3.21Å; L185-T187 HydrophobicContact CB-CG2 4.05Å; T187-P189 WeakPolarHBondContact O-CD 3.32Å
188E95.6Very high89.7Confident63 Ų6339.4 Ų39.429%0.29421%0.21SC..  trans-100.392.6176.8-76.6165.8-127.100111.7L181 N182 N183 Y206L181-E188 CarbonylContact C-O 3.17Å; L181-E188 WeakPolarHBondContact CA-O 3.42Å; N182-E188 HydrophobicContact CB-CB 3.82Å; N182-E188 WeakPolarHBondContact CB-O 3.48Å; N182-E188 PolarHBondContact N-O 3.07Å; N182-E188 PolarHBondContact ND2-OE2 3.1Å; N183-E188 HydrophobicContact CB-CB 4.38Å; N183-E188 HydrophobicContact CB-CG 4.41Å; N183-E188 WeakPolarHBondContact CB-OE1 3.22Å; N183-E188 VanDerWaalsContact ND2-CD 3.3Å; N183-E188 VanDerWaalsContact ND2-CG 3.33Å; N183-E188 WeakPolarHBondContact ND2-CG 3.35Å; N183-E188 PolarHBondContact ND2-OE1 3.43Å; N183-E188 PolarHBondContact OD1-N 2.9Å; E188-Y206 HydrophobicContact CB-CE2 4.35Å; E188-Y206 HydrophobicContact CG-CE2 4.02Å
189P97.4Very high87.7Confident13 Ų1348.5 Ų48.58%0.08425%0.252CS..EExtended strand (participates in β ladder)trans-72.7136.8173.830.6-36.2000112.2L181 T187 L211 P214 F216L181-P189 HydrophobicContact CD2-CB 4.16Å; T187-P189 WeakPolarHBondContact O-CD 3.32Å; P189-L211 HydrophobicContact CB-CB 4.05Å; P189-L211 HydrophobicContact CB-CD1 4.14Å; P189-L211 HydrophobicContact CG-CB 3.82Å; P189-P214 HydrophobicContact CB-CG 3.38Å; P189-P214 HydrophobicContact CG-CG 4.12Å; P189-F216 HydrophobicContact CB-CE2 4.27Å; P189-F216 HydrophobicContact CB-CZ 4.24Å
190V97.5Very high86.6Confident9 Ų951.4 Ų51.46%0.05526%0.264CS..EExtended strand (participates in β ladder)trans-137.4136.4177.1710000111.7A179 T180 N182 L192 K203 S204A179-V190 WeakPolarHBondContact CA-O 3.36Å; T180-V190 PolarHBondContact N-O 3.11Å; T180-V190 PolarHBondContact O-N 3.06Å; N182-V190 HydrophobicContact CB-CB 4.31Å; N182-V190 HydrophobicContact CB-CG1 3.91Å; V190-L192 HydrophobicContact CG2-CB 4.19Å; V190-K203 HydrophobicContact CG2-CB 3.9Å; V190-S204 WeakPolarHBondContact CA-OG 3.42Å
191I98.4Very high86.2Confident0 Ų053.6 Ų53.60%028%0.279CS..EExtended strand (participates in β ladder)trans-105.9117.1159.2-67.4169.3000106.7S178 A179 K203 S204 L211 F216 F238 W276 F279S178-I191 WeakPolarHBondContact O-CA 3.5Å; A179-I191 HydrophobicContact CB-CG1 3.81Å; I191-K203 CarbonylContact O-C 3.57Å; I191-K203 WeakPolarHBondContact O-CA 3.4Å; I191-S204 PolarHBondContact N-OG 3.11Å; I191-S204 PolarHBondContact O-N 2.98Å; I191-L211 HydrophobicContact CD1-CD1 4.25Å; I191-L211 HydrophobicContact CD1-CD2 4Å; I191-L211 HydrophobicContact CG1-CD1 4.13Å; I191-F216 HydrophobicContact CD1-CE1 4.35Å; I191-F216 HydrophobicContact CG1-CE1 4.11Å; I191-F216 HydrophobicContact CG1-CZ 4.44Å; I191-F238 HydrophobicContact CD1-CB 4.41Å; I191-F238 HydrophobicContact CD1-CD2 4.37Å; I191-F238 HydrophobicContact CD1-CG 4.31Å; I191-F238 HydrophobicContact CG2-CD2 4.01Å; I191-F238 HydrophobicContact CG2-CE1 4.1Å; I191-F238 HydrophobicContact CG2-CE2 3.52Å; I191-F238 HydrophobicContact CG2-CG 4.47Å; I191-F238 HydrophobicContact CG2-CZ 3.57Å; I191-W276 PolarHBondContact O-NE1 3.23Å; I191-F279 HydrophobicContact CD1-CD2 4.46Å; I191-F279 HydrophobicContact CD1-CE2 3.67Å; I191-F279 HydrophobicContact CD1-CZ 4.41Å
192L96Very high86Confident11 Ų1153.1 Ų53.16%0.05828%0.277CS..EExtended strand (participates in β ladder)trans-125.4140.3-164.6-178.472000110.6G157 K158 Y177 S178 V190 N194 M202 K203G157-L192 WeakPolarHBondContact O-CD2 3.48Å; K158-L192 HydrophobicContact CG-CD2 4.38Å; Y177-L192 CarbonylContact C-O 3.45Å; Y177-L192 WeakPolarHBondContact CA-O 3.23Å; S178-L192 PolarHBondContact N-O 3.07Å; S178-L192 PolarHBondContact O-N 2.88Å; V190-L192 HydrophobicContact CG2-CB 4.19Å; L192-N194 HydrophobicContact CD2-CB 4.11Å; L192-N194 HydrophobicContact CG-CB 4.21Å; L192-M202 CarbonylContact C-O 3.58Å; L192-M202 WeakPolarHBondContact CA-O 3.39Å; L192-K203 HydrophobicContact CD1-CB 3.98Å
193R96Very high86.1Confident6 Ų656 Ų562%0.02329%0.287CS..EExtended strand (participates in β ladder)trans-111.7131.1155.9-179.5176.693.6-136.4-8.4109.6E175 L176 Y177 S201 M202 K263 D265 W276E175-R193 HydrophobicContact CB-CG 3.91Å; E175-R193 WeakPolarHBondContact OE1-CD 3.38Å; E175-R193 IonicContact OE1-CZ 3.23Å; E175-R193 IonicContact OE1-NE 3.82Å; E175-R193 PolarHBondContact OE1-NE 2.63Å; E175-R193 IonicContact OE1-NH2 2.81Å; E175-R193 WeakPolarHBondContact OE2-CD 3.4Å; E175-R193 IonicContact OE2-CZ 3.05Å; E175-R193 IonicContact OE2-NE 3.52Å; E175-R193 PolarHBondContact OE2-NE 2.54Å; L176-R193 WeakPolarHBondContact O-CA 3.28Å; Y177-R193 HydrophobicContact CD1-CB 4.19Å; Y177-R193 HydrophobicContact CD1-CG 4.37Å; Y177-R193 HydrophobicContact CD2-CG 4.48Å; Y177-R193 HydrophobicContact CE1-CB 4.18Å; Y177-R193 HydrophobicContact CE1-CG 4.11Å; Y177-R193 HydrophobicContact CE2-CG 4.19Å; Y177-R193 WeakPolarHBondContact OH-CD 3.11Å; Y177-R193 PolarHBondContact OH-NH1 2.87Å; R193-S201 VanDerWaalsContact O-CA 3.31Å; R193-S201 WeakPolarHBondContact O-CA 3.48Å; R193-S201 WeakPolarHBondContact O-CB 3.45Å; R193-M202 HydrophobicContact CB-CB 4.25Å; R193-M202 PolarHBondContact N-O 3.27Å; R193-M202 PolarHBondContact O-N 3.21Å; R193-M202 VanDerWaalsContact O-N 3.08Å; R193-K263 PolarHBondContact NH1-O 2.9Å; R193-D265 PolarHBondContact NH1-O 2.79Å; R193-D265 PolarHBondContact NH2-O 2.88Å; R193-W276 HydrophobicContact CB-CH2 3.47Å; R193-W276 VanDerWaalsContact CB-CH2 3.47Å; R193-W276 HydrophobicContact CB-CZ2 3.67Å; R193-W276 HydrophobicContact CG-CH2 4.44Å
194N89.5Confident86.3Confident51 Ų5155.2 Ų55.227%0.27328%0.283SS..EExtended strand (participates in β ladder)trans-148.7169.5-177.7-159.6-20.2000108.6K158 L176 L192K158-N194 VanDerWaalsContact CE-ND2 3.27Å; K158-N194 WeakPolarHBondContact CE-ND2 3.5Å; L176-N194 WeakPolarHBondContact CA-O 3.22Å; L176-N194 PolarHBondContact N-O 3.08Å; L176-N194 PolarHBondContact O-N 2.89Å; L192-N194 HydrophobicContact CD2-CB 4.11Å; L192-N194 HydrophobicContact CG-CB 4.21Å
195L78.8Confident86.5Confident21 Ų2154 Ų5411%0.1128%0.278CS..  trans62.4163.6-163.2-41-178.9000112.8Y120 Y126 E153 L176Y120-L195 HydrophobicContact CD2-CD1 4.42Å; Y120-L195 HydrophobicContact CE2-CD1 4.22Å; Y126-L195 HydrophobicContact CD1-CD1 4.18Å; Y126-L195 HydrophobicContact CD2-CD1 4.04Å; Y126-L195 HydrophobicContact CE1-CD1 3.96Å; Y126-L195 HydrophobicContact CE2-CD1 3.78Å; Y126-L195 HydrophobicContact CE2-CD2 4.09Å; Y126-L195 HydrophobicContact CG-CD1 4.21Å; E153-L195 WeakPolarHBondContact OE2-CD2 3.38Å; L176-L195 HydrophobicContact CB-CD1 3.81Å; L176-L195 HydrophobicContact CB-CG 4.03Å
196G70.8Confident86.6Confident26 Ų2655 Ų5527%0.26827%0.274SS..SBendtrans114.4179.7-179.700000113.7K174K174-G196 PolarHBondContact O-N 3.17Å
197Q58.7Low86.8Confident186 Ų18657.6 Ų57.687%0.86928%0.284SS*.SBendtrans-81.3-20.1178.5-70.8-178.4-39.300113.2H199Q197-H199 PolarHBondContact O-N 2.7Å
198Q59.4Low86.9Confident86 Ų8657.1 Ų57.140%0.40228%0.282SS..SBendtrans-83.2106173.2-62-156.421.700109Y200Q198-Y200 HydrophobicContact CB-CD1 4.25Å; Q198-Y200 HydrophobicContact CB-CE1 3.87Å; Q198-Y200 PolarHBondContact O-N 2.97Å; Q198-Y200 VanDerWaalsContact OE1-CZ 3.28Å; Q198-Y200 PolarHBondContact OE1-OH 3.15Å
199H56.9Low86.8Confident192 Ų19255.4 Ų55.489%0.88928%0.278SS*.  trans-70.831.2-172.6-61.1-72.4000115.3Q197Q197-H199 PolarHBondContact O-N 2.7Å
200Y75.6Confident86.8Confident61 Ų6154.9 Ų54.924%0.23928%0.275CS..SBendtrans-137.5131.7174.965.9-82.4000111.4Q198 M202 L266 K274Q198-Y200 HydrophobicContact CB-CD1 4.25Å; Q198-Y200 HydrophobicContact CB-CE1 3.87Å; Q198-Y200 PolarHBondContact O-N 2.97Å; Q198-Y200 VanDerWaalsContact OE1-CZ 3.28Å; Q198-Y200 PolarHBondContact OE1-OH 3.15Å; Y200-M202 HydrophobicContact CE2-CG 4.23Å; Y200-M202 HydrophobicContact CE2-SD 4.23Å; Y200-L266 WeakPolarHBondContact OH-CB 3.31Å; Y200-K274 HydrophobicContact CD2-CG 4.13Å
201S87.6Confident86.8Confident46 Ų4654.9 Ų54.932%0.32227%0.274SS..  trans-79.8142.1177.351.90000111.9R193R193-S201 VanDerWaalsContact O-CA 3.31Å; R193-S201 WeakPolarHBondContact O-CA 3.48Å; R193-S201 WeakPolarHBondContact O-CB 3.45Å
202M93.2Very high86.7Confident1 Ų155.7 Ų55.71%0.00528%0.279CS..EExtended strand (participates in β ladder)trans-105.8129.8177.1-80.2-71.6-72.100109.2L192 R193 Y200 D265 K274 K275 W276L192-M202 CarbonylContact C-O 3.58Å; L192-M202 WeakPolarHBondContact CA-O 3.39Å; R193-M202 HydrophobicContact CB-CB 4.25Å; R193-M202 PolarHBondContact N-O 3.27Å; R193-M202 PolarHBondContact O-N 3.21Å; R193-M202 VanDerWaalsContact O-N 3.08Å; Y200-M202 HydrophobicContact CE2-CG 4.23Å; Y200-M202 HydrophobicContact CE2-SD 4.23Å; M202-D265 VanDerWaalsContact CE-OD1 3.24Å; M202-D265 WeakPolarHBondContact CE-OD1 3.11Å; M202-K274 VanDerWaalsContact SD-C 3.55Å; M202-K275 VanDerWaalsContact CE-C 3.49Å; M202-K275 WeakPolarHBondContact CE-O 3.13Å; M202-W276 HydrophobicContact CB-CD2 4.38Å; M202-W276 HydrophobicContact CB-CE3 4.31Å; M202-W276 HydrophobicContact CB-CH2 3.83Å; M202-W276 HydrophobicContact CB-CZ2 3.89Å; M202-W276 HydrophobicContact CB-CZ3 4.04Å; M202-W276 HydrophobicContact CE-CD2 4.1Å; M202-W276 HydrophobicContact CE-CE3 3.61Å; M202-W276 HydrophobicContact CE-CZ3 4.07Å
203K95.4Very high86.7Confident97 Ų9761.6 Ų61.642%0.42231%0.306SS..EExtended strand (participates in β ladder)trans-137.9159.5-175.859.4-173.8172.8-176.10114.5V190 I191 L192 K274 K275 W276V190-K203 HydrophobicContact CG2-CB 3.9Å; I191-K203 CarbonylContact O-C 3.57Å; I191-K203 WeakPolarHBondContact O-CA 3.4Å; L192-K203 HydrophobicContact CD1-CB 3.98Å; K203-K274 PolarHBondContact N-O 2.89Å; K203-K275 HydrophobicContact CG-CD 3.85Å; K203-K275 VanDerWaalsContact O-CA 3.26Å; K203-K275 WeakPolarHBondContact O-CA 3.38Å; K203-K275 WeakPolarHBondContact O-CD 3.46Å; K203-W276 VanDerWaalsContact C-CD1 3.43Å; K203-W276 PolarHBondContact O-N 3.19Å
204S97.5Very high86.8Confident5 Ų561.7 Ų61.74%0.03531%0.307CS..  trans-61.9158.9170.550.90000112.8V190 I191 K275V190-S204 WeakPolarHBondContact CA-OG 3.42Å; I191-S204 PolarHBondContact N-OG 3.11Å; I191-S204 PolarHBondContact O-N 2.98Å; S204-K275 WeakPolarHBondContact O-CD 3.35Å; S204-K275 PolarHBondContact O-NZ 2.93Å
205E96.3Very high87.2Confident27 Ų2762 Ų6213%0.12631%0.309CS..  trans-74.9144165.1-71.1-76.6-139.800111.6L207 W210 L272 K275 K396E205-L207 VanDerWaalsContact C-N 3.27Å; E205-L207 HydrophobicContact CB-CD1 4.15Å; E205-L207 HydrophobicContact CB-CG 4.27Å; E205-L207 PolarHBondContact O-N 3.42Å; E205-L207 VanDerWaalsContact O-N 3.1Å; E205-W210 HydrophobicContact CB-CD2 3.72Å; E205-W210 HydrophobicContact CB-CE3 4.09Å; E205-W210 HydrophobicContact CB-CG 4.12Å; E205-W210 HydrophobicContact CB-CH2 4.25Å; E205-W210 HydrophobicContact CB-CZ2 3.93Å; E205-W210 HydrophobicContact CB-CZ3 4.34Å; E205-W210 HydrophobicContact CG-CD2 4.39Å; E205-W210 HydrophobicContact CG-CH2 3.92Å; E205-W210 HydrophobicContact CG-CZ2 3.66Å; E205-W210 HydrophobicContact CG-CZ3 4.42Å; E205-W210 VanDerWaalsContact N-CE3 3.29Å; E205-L272 HydrophobicContact CG-CD2 3.69Å; E205-K275 HydrophobicContact CG-CB 4.47Å; E205-K275 HydrophobicContact CG-CD 4.36Å; E205-K275 HydrophobicContact CG-CG 4.28Å; E205-K275 VanDerWaalsContact OE2-CE 3.29Å; E205-K275 WeakPolarHBondContact OE2-CE 3.2Å; E205-K275 IonicContact OE2-NZ 2.72Å; E205-K275 PolarHBondContact OE2-NZ 3.39Å; E205-K396 WeakPolarHBondContact OE1-CE 3.32Å; E205-K396 IonicContact OE1-NZ 3.42Å; E205-K396 PolarHBondContact OE1-NZ 3.36Å
206Y94.8Very high88.1Confident156 Ų15661.2 Ų61.261%0.61231%0.305SS*.SBendtrans-87.674177-173.4-120.6000108.9E188E188-Y206 HydrophobicContact CB-CE2 4.35Å; E188-Y206 HydrophobicContact CG-CE2 4.02Å
207L95.1Very high89.4Confident70 Ų7061.3 Ų61.337%0.36630%0.3SS..  trans-138.8133.8-179-67.1173.9000108.6E205 A209 W210 L211 K396E205-L207 VanDerWaalsContact C-N 3.27Å; E205-L207 HydrophobicContact CB-CD1 4.15Å; E205-L207 HydrophobicContact CB-CG 4.27Å; E205-L207 PolarHBondContact O-N 3.42Å; E205-L207 VanDerWaalsContact O-N 3.1Å; L207-A209 PolarHBondContact O-N 2.77Å; L207-A209 VanDerWaalsContact O-N 3.14Å; L207-W210 WeakPolarHBondContact O-CA 3.44Å; L207-W210 WeakPolarHBondContact O-CB 3.39Å; L207-W210 PolarHBondContact O-N 3.37Å; L207-L211 PolarHBondContact O-N 2.76Å; L207-K396 HydrophobicContact CD1-CG 4.49Å
208P93.6Very high91.3Very high72 Ų7252.8 Ų52.847%0.46826%0.262SS..THydrogen-bonded Turntrans-54.9-34177.4-29.937.2000113.7W210 L211 N212 L245P208-W210 PolarHBondContact O-N 2.77Å; P208-W210 VanDerWaalsContact O-N 3.16Å; P208-L211 CarbonylContact O-C 3.56Å; P208-L211 PolarHBondContact O-N 3.12Å; P208-N212 HydrophobicContact CB-CB 4.5Å; P208-L245 VanDerWaalsContact C-CD1 3.5Å; P208-L245 HydrophobicContact CB-CD1 3.72Å; P208-L245 WeakPolarHBondContact O-CD1 3.3Å
209A94.3Very high93.1Very high27 Ų2750 Ų5022%0.22325%0.252CS..THydrogen-bonded Turntrans-57-30.217400000113.1L207 K281 W356 P399L207-A209 PolarHBondContact O-N 2.77Å; L207-A209 VanDerWaalsContact O-N 3.14Å; A209-K281 WeakPolarHBondContact O-CE 3.36Å; A209-K281 PolarHBondContact O-NZ 2.94Å; A209-W356 HydrophobicContact CB-CH2 4.27Å; A209-P399 HydrophobicContact CB-CG 4.37Å; A209-P399 VanDerWaalsContact O-CG 3.27Å; A209-P399 WeakPolarHBondContact O-CG 3.46Å
210W97.4Very high95.1Very high2 Ų241.2 Ų41.21%0.00821%0.213CC..THydrogen-bonded Turntrans-84.5-52.6177-77.655.2000112.3E205 L207 P208 L272 W276 F279 K281 K396 P399E205-W210 HydrophobicContact CB-CD2 3.72Å; E205-W210 HydrophobicContact CB-CE3 4.09Å; E205-W210 HydrophobicContact CB-CG 4.12Å; E205-W210 HydrophobicContact CB-CH2 4.25Å; E205-W210 HydrophobicContact CB-CZ2 3.93Å; E205-W210 HydrophobicContact CB-CZ3 4.34Å; E205-W210 HydrophobicContact CG-CD2 4.39Å; E205-W210 HydrophobicContact CG-CH2 3.92Å; E205-W210 HydrophobicContact CG-CZ2 3.66Å; E205-W210 HydrophobicContact CG-CZ3 4.42Å; E205-W210 VanDerWaalsContact N-CE3 3.29Å; L207-W210 WeakPolarHBondContact O-CA 3.44Å; L207-W210 WeakPolarHBondContact O-CB 3.39Å; L207-W210 PolarHBondContact O-N 3.37Å; P208-W210 PolarHBondContact O-N 2.77Å; P208-W210 VanDerWaalsContact O-N 3.16Å; W210-L272 HydrophobicContact CH2-CD2 4.02Å; W210-L272 HydrophobicContact CZ2-CD2 3.95Å; W210-W276 HydrophobicContact CH2-CB 4.43Å; W210-W276 WeakPolarHBondContact CH2-O 3.5Å; W210-W276 HydrophobicContact CZ3-CB 4.25Å; W210-F279 HydrophobicContact CB-CE1 4.1Å; W210-F279 AromaticContact CD2-CD1 3.72Å; W210-F279 HydrophobicContact CD2-CD1 3.72Å; W210-F279 HydrophobicContact CD2-CE1 4.04Å; W210-F279 HydrophobicContact CE3-CB 4.16Å; W210-F279 AromaticContact CE3-CD1 3.24Å; W210-F279 HydrophobicContact CE3-CD1 3.24Å; W210-F279 AromaticContact CE3-CE1 3.73Å; W210-F279 HydrophobicContact CE3-CE1 3.73Å; W210-F279 AromaticContact CE3-CG 3.78Å; W210-F279 HydrophobicContact CE3-CG 3.78Å; W210-F279 HydrophobicContact CG-CD1 4.34Å; W210-F279 HydrophobicContact CG-CE1 4.22Å; W210-F279 HydrophobicContact CH2-CB 4.07Å; W210-F279 HydrophobicContact CH2-CD1 4.37Å; W210-F279 HydrophobicContact CZ3-CB 3.6Å; W210-F279 AromaticContact CZ3-CD1 3.62Å; W210-F279 HydrophobicContact CZ3-CD1 3.62Å; W210-F279 AromaticContact CZ3-CG 3.74Å; W210-F279 HydrophobicContact CZ3-CG 3.74Å; W210-K281 WeakPolarHBondContact O-CD 2.95Å; W210-K281 WeakPolarHBondContact O-CE 3.35Å; W210-K281 PolarHBondContact O-NZ 3.41Å; W210-K396 PolarHBondContact NE1-O 3.03Å; W210-P399 HydrophobicContact CG-CB 4.39Å; W210-P399 HydrophobicContact CG-CG 4.22Å
211L97.9Very high96.1Very high9 Ų940.3 Ų40.35%0.04721%0.212CC..  trans-146.7121.1-178.3-67.1171.4000108.8P189 I191 L207 P208 P214 F216 F240 F279P189-L211 HydrophobicContact CB-CB 4.05Å; P189-L211 HydrophobicContact CB-CD1 4.14Å; P189-L211 HydrophobicContact CG-CB 3.82Å; I191-L211 HydrophobicContact CD1-CD1 4.25Å; I191-L211 HydrophobicContact CD1-CD2 4Å; I191-L211 HydrophobicContact CG1-CD1 4.13Å; L207-L211 PolarHBondContact O-N 2.76Å; P208-L211 CarbonylContact O-C 3.56Å; P208-L211 PolarHBondContact O-N 3.12Å; L211-P214 HydrophobicContact CB-CG 4.25Å; L211-P214 HydrophobicContact CD2-CG 4.41Å; L211-F216 HydrophobicContact CD1-CZ 4.32Å; L211-F216 HydrophobicContact CD2-CE1 4.33Å; L211-F216 HydrophobicContact CD2-CZ 4.41Å; L211-F240 HydrophobicContact CD2-CE1 4.25Å; L211-F240 HydrophobicContact CD2-CE2 3.9Å; L211-F240 HydrophobicContact CD2-CZ 3.63Å; L211-F279 HydrophobicContact CD2-CZ 4.31Å
212N96.7Very high96.6Very high18 Ų1838.3 Ų38.310%0.09620%0.198CC..SBendtrans-123.294.5-176.1-166.244.2000111.9P208 E242 R243 L245P208-N212 HydrophobicContact CB-CB 4.5Å; N212-E242 PolarHBondContact N-OE2 3.03Å; N212-E242 VanDerWaalsContact N-OE2 3.11Å; N212-E242 WeakPolarHBondContact O-CB 3.38Å; N212-R243 WeakPolarHBondContact ND2-CB 3.29Å; N212-R243 WeakPolarHBondContact ND2-CG 3.4Å; N212-R243 PolarHBondContact ND2-O 2.85Å; N212-R243 PolarHBondContact O-N 2.76Å; N212-L245 HydrophobicContact CB-CD1 4.43Å; N212-L245 HydrophobicContact CB-CG 4.45Å; N212-L245 WeakPolarHBondContact ND2-CD2 3.48Å
213E96Very high96.7Very high134 Ų13445.2 Ų45.263%0.62622%0.224SC*.SBendtrans52.449.8-177.8-55.8176.7138.600114R243E213-R243 WeakPolarHBondContact OE2-CD 3.39Å; E213-R243 IonicContact OE2-NH1 3Å
214P97.5Very high96.7Very high8 Ų840.6 Ų40.65%0.05220%0.204CC..  trans-76.6141.2-172.833.3-38.3000114.6P189 L211 F216 F240 S241 E242P189-P214 HydrophobicContact CB-CG 3.38Å; P189-P214 HydrophobicContact CG-CG 4.12Å; L211-P214 HydrophobicContact CB-CG 4.25Å; L211-P214 HydrophobicContact CD2-CG 4.41Å; P214-F216 HydrophobicContact CB-CE1 4.11Å; P214-F216 HydrophobicContact CB-CE2 4.25Å; P214-F216 HydrophobicContact CB-CZ 3.96Å; P214-F216 HydrophobicContact CG-CD2 4.47Å; P214-F216 HydrophobicContact CG-CE1 4.07Å; P214-F216 HydrophobicContact CG-CE2 3.66Å; P214-F216 HydrophobicContact CG-CZ 3.43Å; P214-F216 VanDerWaalsContact CG-CZ 3.43Å; P214-F240 HydrophobicContact CB-CB 4.44Å; P214-F240 HydrophobicContact CB-CD2 3.68Å; P214-F240 HydrophobicContact CB-CE2 4.23Å; P214-F240 HydrophobicContact CB-CG 4.32Å; P214-S241 CarbonylContact C-O 3.52Å; P214-S241 WeakPolarHBondContact CA-O 3.49Å; P214-E242 HydrophobicContact CB-CB 4.21Å
215D97.4Very high96.5Very high58 Ų5842.6 Ų42.631%0.3122%0.218SC..EExtended strand (participates in β ladder)trans-99.3107.2163.7-17329.8000109G166 F240 S241 R299G166-D215 WeakPolarHBondContact CA-OD1 3.35Å; G166-D215 PolarHBondContact N-OD1 2.87Å; D215-F240 VanDerWaalsContact O-CA 3.23Å; D215-F240 WeakPolarHBondContact O-CA 3.17Å; D215-F240 VanDerWaalsContact O-CB 3.22Å; D215-F240 WeakPolarHBondContact O-CB 3.3Å; D215-S241 PolarHBondContact N-O 2.89Å; D215-S241 PolarHBondContact O-N 2.96Å; D215-R299 IonicContact OD2-NH1 2.79Å
216F98.4Very high96.3Very high5 Ų545 Ų452%0.02224%0.238CC..EExtended strand (participates in β ladder)trans-81.4127.4-173.9-64-73.7000112.3G166 H167 T168 A179 T180 P189 I191 L211 P214 F240G166-F216 CarbonylContact C-O 3.53Å; G166-F216 VanDerWaalsContact CA-O 3.24Å; G166-F216 WeakPolarHBondContact CA-O 3.31Å; H167-F216 PolarHBondContact N-O 3.39Å; H167-F216 VanDerWaalsContact N-O 3.13Å; T168-F216 HydrophobicContact CG2-CB 4.49Å; A179-F216 HydrophobicContact CB-CD1 3.56Å; A179-F216 HydrophobicContact CB-CE1 3.75Å; A179-F216 HydrophobicContact CB-CG 3.96Å; A179-F216 HydrophobicContact CB-CZ 4.28Å; T180-F216 WeakPolarHBondContact O-CE2 3.36Å; P189-F216 HydrophobicContact CB-CE2 4.27Å; P189-F216 HydrophobicContact CB-CZ 4.24Å; I191-F216 HydrophobicContact CD1-CE1 4.35Å; I191-F216 HydrophobicContact CG1-CE1 4.11Å; I191-F216 HydrophobicContact CG1-CZ 4.44Å; L211-F216 HydrophobicContact CD1-CZ 4.32Å; L211-F216 HydrophobicContact CD2-CE1 4.33Å; L211-F216 HydrophobicContact CD2-CZ 4.41Å; P214-F216 HydrophobicContact CB-CE1 4.11Å; P214-F216 HydrophobicContact CB-CE2 4.25Å; P214-F216 HydrophobicContact CB-CZ 3.96Å; P214-F216 HydrophobicContact CG-CD2 4.47Å; P214-F216 HydrophobicContact CG-CE1 4.07Å; P214-F216 HydrophobicContact CG-CE2 3.66Å; P214-F216 HydrophobicContact CG-CZ 3.43Å; P214-F216 VanDerWaalsContact CG-CZ 3.43Å; F216-F240 HydrophobicContact CD1-CB 3.81Å; F216-F240 HydrophobicContact CD1-CD1 4.21Å; F216-F240 HydrophobicContact CD1-CG 4.15Å; F216-F240 HydrophobicContact CE1-CB 4.39Å; F216-F240 HydrophobicContact CE1-CD1 4.23Å; F216-F240 HydrophobicContact CE1-CG 4.27Å; F216-F240 HydrophobicContact CG-CB 4.5Å
217V97.8Very high95.9Very high28 Ų2840.4 Ų40.417%0.1724%0.238CC..EExtended strand (participates in β ladder)trans-113-39.1-167.4175.50000113.6F239 L298 R299 V301V217-F239 WeakPolarHBondContact CB-O 3.23Å; V217-F239 PolarHBondContact N-O 3.32Å; V217-L298 HydrophobicContact CB-CD2 4.24Å; V217-L298 HydrophobicContact CB-CG 4.45Å; V217-L298 HydrophobicContact CG1-CD2 4.3Å; V217-L298 HydrophobicContact CG1-CG 4.16Å; V217-L298 HydrophobicContact CG2-CB 4.45Å; V217-L298 HydrophobicContact CG2-CD2 4.35Å; V217-L298 HydrophobicContact CG2-CG 4.28Å; V217-L298 WeakPolarHBondContact CG2-O 3.46Å; V217-R299 VanDerWaalsContact CG1-C 3.45Å; V217-V301 HydrophobicContact CG1-CG2 4.26Å
218G97.5Very high95.6Very high7 Ų738.8 Ų38.87%0.07223%0.232CC..EExtended strand (participates in β ladder)trans-172.2160.1-172.300000113.6T168 F239T168-G218 VanDerWaalsContact OG1-C 3.28Å; T168-G218 VanDerWaalsContact OG1-CA 3.26Å; T168-G218 WeakPolarHBondContact OG1-CA 3.29Å; G218-F239 PolarHBondContact N-O 2.93Å; G218-F239 PolarHBondContact O-N 3Å
219S98.1Very high95.4Very high26 Ų2643.8 Ų43.818%0.18225%0.249CC..EExtended strand (participates in β ladder)trans-146.7155.4176.552.50000111.8T168 G169 L170 Y237T168-S219 PolarHBondContact OG1-N 3.21Å; T168-S219 VanDerWaalsContact OG1-N 3.16Å; T168-S219 PolarHBondContact OG1-OG 3.21Å; T168-S219 VanDerWaalsContact OG1-OG 3.05Å; G169-S219 WeakPolarHBondContact CA-OG 3.46Å; G169-S219 PolarHBondContact N-OG 2.89Å; L170-S219 VanDerWaalsContact CD2-OG 3.23Å; L170-S219 WeakPolarHBondContact CD2-OG 3.31Å; S219-Y237 CarbonylContact C-O 3.53Å; S219-Y237 WeakPolarHBondContact CA-O 3.34Å; S219-Y237 VanDerWaalsContact CB-O 3.29Å; S219-Y237 WeakPolarHBondContact CB-O 3.35Å
220A98.1Very high95.3Very high8 Ų848 Ų487%0.06627%0.268CS..EExtended strand (participates in β ladder)trans-150.2143.6-175.600000112.7Y237 F239 T303 F314A220-Y237 PolarHBondContact N-O 2.87Å; A220-Y237 PolarHBondContact O-N 3.23Å; A220-F239 HydrophobicContact CB-CE2 4.5Å; A220-T303 HydrophobicContact CB-CG2 4.17Å; A220-T303 WeakPolarHBondContact CB-OG1 3.36Å; A220-F314 HydrophobicContact CB-CE1 4.25Å
221L97.9Very high95Very high43 Ų4349 Ų4923%0.22528%0.279CS..EExtended strand (participates in β ladder)trans-86.7125.4165.3168.364.3000109.3L170 V172 R223 D234 I236L170-L221 HydrophobicContact CD1-CB 3.77Å; V172-L221 HydrophobicContact CG1-CD1 4.32Å; V172-L221 HydrophobicContact CG1-CD2 3.94Å; V172-L221 HydrophobicContact CG2-CB 4.23Å; V172-L221 HydrophobicContact CG2-CD2 4.07Å; L221-R223 HydrophobicContact CD1-CG 4.24Å; L221-R223 HydrophobicContact CD2-CG 4.08Å; L221-R223 HydrophobicContact CG-CG 4.05Å; L221-D234 HydrophobicContact CD1-CB 3.95Å; L221-I236 HydrophobicContact CB-CD1 4.14Å; L221-I236 HydrophobicContact CD1-CD1 3.61Å; L221-I236 HydrophobicContact CG-CD1 4.46Å
222V97.6Very high94.8Very high4 Ų449.8 Ų49.82%0.02428%0.283CS..EExtended strand (participates in β ladder)trans-113.1118.1166.4-174.90000108.3E224 K235 Y237 W309 F314 I335V222-E224 VanDerWaalsContact C-N 3.26Å; V222-E224 HydrophobicContact CB-CG 4.35Å; V222-E224 HydrophobicContact CG1-CG 3.66Å; V222-E224 PolarHBondContact O-N 3.3Å; V222-K235 PolarHBondContact N-O 2.99Å; V222-K235 PolarHBondContact O-N 3.48Å; V222-Y237 HydrophobicContact CB-CD2 4.06Å; V222-Y237 HydrophobicContact CB-CE2 4Å; V222-Y237 HydrophobicContact CG2-CD2 3.57Å; V222-Y237 HydrophobicContact CG2-CE2 3.83Å; V222-Y237 HydrophobicContact CG2-CG 4.46Å; V222-W309 HydrophobicContact CG1-CB 4.26Å; V222-W309 HydrophobicContact CG1-CE3 4.27Å; V222-F314 HydrophobicContact CG2-CE1 4.44Å; V222-F314 HydrophobicContact CG2-CZ 3.95Å; V222-I335 HydrophobicContact CG1-CD1 4.25Å; V222-I335 HydrophobicContact CG1-CG1 4.15Å; V222-I335 HydrophobicContact CG2-CD1 4.21Å
223R96.1Very high94.7Very high145 Ų14550.5 Ų50.555%0.54729%0.287SS..  trans-83.664.8-178.5-66.5-165.5179.4103.2-0.8112.5L221 S225 S226 D234L221-R223 HydrophobicContact CD1-CG 4.24Å; L221-R223 HydrophobicContact CD2-CG 4.08Å; L221-R223 HydrophobicContact CG-CG 4.05Å; R223-S225 PolarHBondContact O-N 2.75Å; R223-S226 VanDerWaalsContact O-CB 3.27Å; R223-S226 WeakPolarHBondContact O-CB 3.29Å; R223-S226 PolarHBondContact O-N 2.84Å; R223-S226 VanDerWaalsContact O-N 3.07Å; R223-D234 WeakPolarHBondContact CA-OD1 3.47Å; R223-D234 WeakPolarHBondContact CB-OD1 3.31Å
224E94.6Very high94.8Very high1 Ų144.3 Ų44.31%0.00526%0.258CS..THydrogen-bonded Turntrans-63.6-22-179.5-61.1-170.5-164.400113V222 S226 K235 Y237 W309 K339V222-E224 VanDerWaalsContact C-N 3.26Å; V222-E224 HydrophobicContact CB-CG 4.35Å; V222-E224 HydrophobicContact CG1-CG 3.66Å; V222-E224 PolarHBondContact O-N 3.3Å; E224-S226 PolarHBondContact O-N 3.08Å; E224-K235 WeakPolarHBondContact OE2-CD 3.14Å; E224-K235 WeakPolarHBondContact OE2-CE 3.47Å; E224-K235 IonicContact OE2-NZ 3.33Å; E224-K235 PolarHBondContact OE2-NZ 2.79Å; E224-Y237 PolarHBondContact OE1-OH 3.41Å; E224-W309 HydrophobicContact CB-CD2 4.38Å; E224-W309 HydrophobicContact CB-CH2 4.46Å; E224-W309 HydrophobicContact CB-CZ2 4.26Å; E224-W309 HydrophobicContact CG-CD2 4.12Å; E224-W309 HydrophobicContact CG-CE3 3.86Å; E224-W309 HydrophobicContact CG-CH2 4.22Å; E224-W309 HydrophobicContact CG-CZ2 4.44Å; E224-W309 HydrophobicContact CG-CZ3 3.92Å; E224-W309 PolarHBondContact O-NE1 3.06Å; E224-K339 WeakPolarHBondContact OE2-CE 3.5Å
225S94.1Very high94.8Very high47 Ų4744 Ų4433%0.32926%0.256SS..THydrogen-bonded Turntrans-61.3-27.4171.770.20000113.7R223 G227 S228 D232 D234R223-S225 PolarHBondContact O-N 2.75Å; S225-G227 PolarHBondContact O-N 2.88Å; S225-S228 WeakPolarHBondContact O-CB 3.3Å; S225-S228 PolarHBondContact O-N 2.89Å; S225-D232 VanDerWaalsContact CA-O 3.23Å; S225-D232 WeakPolarHBondContact CA-O 3.19Å; S225-D232 VanDerWaalsContact CB-O 3.26Å; S225-D232 WeakPolarHBondContact CB-O 3.42Å; S225-D234 WeakPolarHBondContact CB-OD1 3.22Å; S225-D234 PolarHBondContact OG-OD1 3.4Å
226S92Very high94.8Very high77 Ų7741.3 Ų41.354%0.53824%0.241SC..THydrogen-bonded Turntrans-68.1103.2-175-179.90000111.2R223 E224 W309R223-S226 VanDerWaalsContact O-CB 3.27Å; R223-S226 WeakPolarHBondContact O-CB 3.29Å; R223-S226 PolarHBondContact O-N 2.84Å; R223-S226 VanDerWaalsContact O-N 3.07Å; E224-S226 PolarHBondContact O-N 3.08Å; S226-W309 PolarHBondContact O-NE1 3.13Å
227G85.3Confident94.9Very high60 Ų6041 Ų4162%0.61924%0.24SC*.THydrogen-bonded Turntrans74.129.6-17400000113.4S225 R310S225-G227 PolarHBondContact O-N 2.88Å; G227-R310 PolarHBondContact O-NH2 3.3Å
228S89Confident94.9Very high35 Ų3539.7 Ų39.725%0.24523%0.232CC..  trans-81126.5168.1-171.30000110.4S225 D232S225-S228 WeakPolarHBondContact O-CB 3.3Å; S225-S228 PolarHBondContact O-N 2.89Å; S228-D232 WeakPolarHBondContact OG-CB 3.48Å; S228-D232 PolarHBondContact OG-N 2.82Å
229Q90.4Very high95Very high178 Ų17839.4 Ų39.483%0.83223%0.229SC*.SBendtrans-83.7-29.2174.2-65.5-179.1-3.800111.3G231 N374Q229-G231 VanDerWaalsContact C-N 3.3Å; Q229-G231 PolarHBondContact O-N 3.34Å; Q229-N374 PolarHBondContact O-ND2 2.87Å; Q229-N374 VanDerWaalsContact O-ND2 3.08Å
230D91Very high95Very high115 Ų11538.2 Ų38.262%0.61522%0.22SC*.SBendtrans-85.63.1-176.6-49.4-57.7000113.4D232 T373 N374D230-D232 VanDerWaalsContact C-N 3.28Å; D230-D232 PolarHBondContact O-N 3.19Å; D230-T373 CarbonylContact O-C 3.59Å; D230-T373 WeakPolarHBondContact O-CA 3.38Å; D230-T373 WeakPolarHBondContact O-CB 3.27Å; D230-N374 PolarHBondContact O-N 3.37Å
231G91.1Very high95Very high22 Ų2238 Ų3823%0.22722%0.219CC..  trans6826.1-17900000114.3Q229 N374Q229-G231 VanDerWaalsContact C-N 3.3Å; Q229-G231 PolarHBondContact O-N 3.34Å; G231-N374 PolarHBondContact N-ND2 2.94Å
232D93.4Very high95Very high26 Ų2636.1 Ų36.114%0.13921%0.209CC..  trans-64.7154.3173.4-166.58.2000111.5S225 S228 D230 K235 C371S225-D232 VanDerWaalsContact CA-O 3.23Å; S225-D232 WeakPolarHBondContact CA-O 3.19Å; S225-D232 VanDerWaalsContact CB-O 3.26Å; S225-D232 WeakPolarHBondContact CB-O 3.42Å; S228-D232 WeakPolarHBondContact OG-CB 3.48Å; S228-D232 PolarHBondContact OG-N 2.82Å; D230-D232 VanDerWaalsContact C-N 3.28Å; D230-D232 PolarHBondContact O-N 3.19Å; D232-K235 IonicContact OD1-NZ 2.68Å; D232-K235 PolarHBondContact OD1-NZ 2.86Å; D232-K235 IonicContact OD2-NZ 3.4Å; D232-K235 PolarHBondContact OD2-NZ 2.87Å; D232-C371 WeakPolarHBondContact OD1-CB 3.26Å
233D95.8Very high94.9Very high33 Ų3339.6 Ų39.618%0.17622%0.221CC..  trans-104.1162.6-171.4-176.131.5000112.7K235 K263 G264 C371D233-K235 PolarHBondContact O-NZ 2.85Å; D233-K263 PolarHBondContact OD2-N 2.83Å; D233-K263 VanDerWaalsContact OD2-N 3.09Å; D233-G264 PolarHBondContact OD2-N 3.08Å; D233-C371 HydrophobicContact CB-CB 3.83Å
234D97.4Very high94.7Very high5 Ų533.1 Ų33.13%0.02720%0.199CC..  trans-58.1144.4167.5-71.3-9.1000110.9L221 R223 S225 K263L221-D234 HydrophobicContact CD1-CB 3.95Å; R223-D234 WeakPolarHBondContact CA-OD1 3.47Å; R223-D234 WeakPolarHBondContact CB-OD1 3.31Å; S225-D234 WeakPolarHBondContact CB-OD1 3.22Å; S225-D234 PolarHBondContact OG-OD1 3.4Å; D234-K263 HydrophobicContact CB-CB 3.95Å; D234-K263 HydrophobicContact CB-CD 3.99Å; D234-K263 WeakPolarHBondContact O-CB 3.42Å; D234-K263 PolarHBondContact O-N 2.94Å; D234-K263 WeakPolarHBondContact OD2-CE 3.49Å; D234-K263 IonicContact OD2-NZ 2.71Å; D234-K263 PolarHBondContact OD2-NZ 3.42Å
235K97.9Very high94.5Very high2 Ų236 Ų361%0.00921%0.214CC..EExtended strand (participates in β ladder)trans-126.5134.7-176.4-63.3178.5-167.461.10111.1V222 E224 D232 D233 Y237 V261 C371V222-K235 PolarHBondContact N-O 2.99Å; V222-K235 PolarHBondContact O-N 3.48Å; E224-K235 WeakPolarHBondContact OE2-CD 3.14Å; E224-K235 WeakPolarHBondContact OE2-CE 3.47Å; E224-K235 IonicContact OE2-NZ 3.33Å; E224-K235 PolarHBondContact OE2-NZ 2.79Å; D232-K235 IonicContact OD1-NZ 2.68Å; D232-K235 PolarHBondContact OD1-NZ 2.86Å; D232-K235 IonicContact OD2-NZ 3.4Å; D232-K235 PolarHBondContact OD2-NZ 2.87Å; D233-K235 PolarHBondContact O-NZ 2.85Å; K235-Y237 HydrophobicContact CB-CD2 4.2Å; K235-Y237 HydrophobicContact CB-CE2 3.69Å; K235-V261 CarbonylContact C-O 3.58Å; K235-V261 WeakPolarHBondContact CA-O 3.2Å; K235-C371 WeakPolarHBondContact CE-SG 3.47Å
236I98.6Very high94.3Very high0 Ų035 Ų350%020%0.204CC..EExtended strand (participates in β ladder)trans-98.7113.8175.5-50.1-55.9000108.1L170 V172 Y177 L221 F238 R260 V261L170-I236 HydrophobicContact CD2-CG2 4Å; V172-I236 HydrophobicContact CG2-CD1 3.89Å; Y177-I236 HydrophobicContact CD1-CB 4.11Å; Y177-I236 HydrophobicContact CD1-CG1 3.68Å; Y177-I236 HydrophobicContact CD1-CG2 4.1Å; Y177-I236 HydrophobicContact CD2-CG1 4.33Å; Y177-I236 HydrophobicContact CE1-CB 4.43Å; Y177-I236 HydrophobicContact CE1-CG1 3.65Å; Y177-I236 HydrophobicContact CE2-CG1 4.35Å; Y177-I236 HydrophobicContact CG-CG1 4.02Å; Y177-I236 HydrophobicContact CG-CG2 4.18Å; L221-I236 HydrophobicContact CB-CD1 4.14Å; L221-I236 HydrophobicContact CD1-CD1 3.61Å; L221-I236 HydrophobicContact CG-CD1 4.46Å; I236-F238 HydrophobicContact CB-CE2 4.22Å; I236-F238 HydrophobicContact CG2-CD2 4.43Å; I236-F238 HydrophobicContact CG2-CE1 4.36Å; I236-F238 HydrophobicContact CG2-CE2 3.69Å; I236-F238 HydrophobicContact CG2-CZ 3.66Å; I236-R260 VanDerWaalsContact O-CA 3.28Å; I236-R260 WeakPolarHBondContact O-CA 3.46Å; I236-V261 HydrophobicContact CB-CG2 4.01Å; I236-V261 PolarHBondContact N-O 3.44Å; I236-V261 PolarHBondContact O-N 2.93Å
237Y98.8Very high94Very high0 Ų034 Ų340%019%0.193CC..EExtended strand (participates in β ladder)trans-92.7139.8179.3-78.8-95.3000110.6S219 A220 V222 E224 K235 V258 A259 R260 F314 I335 V338 F342S219-Y237 CarbonylContact C-O 3.53Å; S219-Y237 WeakPolarHBondContact CA-O 3.34Å; S219-Y237 VanDerWaalsContact CB-O 3.29Å; S219-Y237 WeakPolarHBondContact CB-O 3.35Å; A220-Y237 PolarHBondContact N-O 2.87Å; A220-Y237 PolarHBondContact O-N 3.23Å; V222-Y237 HydrophobicContact CB-CD2 4.06Å; V222-Y237 HydrophobicContact CB-CE2 4Å; V222-Y237 HydrophobicContact CG2-CD2 3.57Å; V222-Y237 HydrophobicContact CG2-CE2 3.83Å; V222-Y237 HydrophobicContact CG2-CG 4.46Å; E224-Y237 PolarHBondContact OE1-OH 3.41Å; K235-Y237 HydrophobicContact CB-CD2 4.2Å; K235-Y237 HydrophobicContact CB-CE2 3.69Å; Y237-V258 HydrophobicContact CD1-CG2 3.65Å; Y237-V258 HydrophobicContact CE1-CG2 4.21Å; Y237-A259 CarbonylContact C-O 3.51Å; Y237-A259 VanDerWaalsContact CA-O 3.3Å; Y237-A259 WeakPolarHBondContact CA-O 3.33Å; Y237-R260 HydrophobicContact CD1-CB 4.07Å; Y237-R260 HydrophobicContact CE1-CB 3.93Å; Y237-R260 HydrophobicContact CE2-CB 4.46Å; Y237-R260 HydrophobicContact CG-CB 4.4Å; Y237-F314 HydrophobicContact CD1-CZ 4.48Å; Y237-F314 HydrophobicContact CG-CZ 4.32Å; Y237-I335 HydrophobicContact CE1-CD1 4.31Å; Y237-I335 HydrophobicContact CE2-CD1 4.01Å; Y237-V338 HydrophobicContact CE1-CG1 3.78Å; Y237-F342 AromaticContact CE1-CE2 3.96Å; Y237-F342 HydrophobicContact CE1-CE2 3.96Å
238F98.8Very high93.4Very high0 Ų038.7 Ų38.70%020%0.203CC..EExtended strand (participates in β ladder)trans-127.1139.7176.9-62.9-86.4000110.3T168 A179 I191 I236 V258 A259 V261T168-F238 HydrophobicContact CG2-CD1 4.36Å; A179-F238 HydrophobicContact CB-CD1 3.67Å; A179-F238 HydrophobicContact CB-CE1 3.92Å; I191-F238 HydrophobicContact CD1-CB 4.41Å; I191-F238 HydrophobicContact CD1-CD2 4.37Å; I191-F238 HydrophobicContact CD1-CG 4.31Å; I191-F238 HydrophobicContact CG2-CD2 4.01Å; I191-F238 HydrophobicContact CG2-CE1 4.1Å; I191-F238 HydrophobicContact CG2-CE2 3.52Å; I191-F238 HydrophobicContact CG2-CG 4.47Å; I191-F238 HydrophobicContact CG2-CZ 3.57Å; I236-F238 HydrophobicContact CB-CE2 4.22Å; I236-F238 HydrophobicContact CG2-CD2 4.43Å; I236-F238 HydrophobicContact CG2-CE1 4.36Å; I236-F238 HydrophobicContact CG2-CE2 3.69Å; I236-F238 HydrophobicContact CG2-CZ 3.66Å; F238-V258 WeakPolarHBondContact O-CA 3.38Å; F238-A259 PolarHBondContact N-O 3.49Å; F238-A259 PolarHBondContact O-N 2.77Å; F238-V261 HydrophobicContact CE2-CG2 4.12Å
239F98.8Very high92.5Very high1 Ų140.2 Ų40.20%0.00421%0.213CC..EExtended strand (participates in β ladder)trans-126.7128.6-175.3-60.8-87.5000109.9V217 G218 A220 V258 L284 L298 V301 F314V217-F239 WeakPolarHBondContact CB-O 3.23Å; V217-F239 PolarHBondContact N-O 3.32Å; G218-F239 PolarHBondContact N-O 2.93Å; G218-F239 PolarHBondContact O-N 3Å; A220-F239 HydrophobicContact CB-CE2 4.5Å; F239-V258 HydrophobicContact CD1-CB 4.02Å; F239-V258 HydrophobicContact CD1-CG2 4Å; F239-V258 HydrophobicContact CE1-CB 3.84Å; F239-V258 HydrophobicContact CE1-CG2 3.47Å; F239-V258 VanDerWaalsContact CE1-CG2 3.47Å; F239-V258 HydrophobicContact CZ-CG2 3.93Å; F239-L284 HydrophobicContact CD1-CD2 4.12Å; F239-L284 HydrophobicContact CE1-CD2 4.48Å; F239-L298 HydrophobicContact CB-CD2 3.88Å; F239-V301 HydrophobicContact CB-CB 4.44Å; F239-V301 HydrophobicContact CB-CG2 3.77Å; F239-V301 HydrophobicContact CD1-CG1 4.43Å; F239-V301 HydrophobicContact CD1-CG2 4.17Å; F239-V301 HydrophobicContact CD2-CB 4.5Å; F239-V301 HydrophobicContact CD2-CG1 4.02Å; F239-V301 HydrophobicContact CE2-CG1 4.18Å; F239-V301 HydrophobicContact CG-CB 4.37Å; F239-V301 HydrophobicContact CG-CG1 4.16Å; F239-V301 HydrophobicContact CG-CG2 3.92Å; F239-V301 HydrophobicContact CZ-CG1 4.46Å; F239-F314 HydrophobicContact CE1-CB 4.5Å; F239-F314 HydrophobicContact CE1-CD1 4.43Å; F239-F314 HydrophobicContact CE1-CD2 4.4Å; F239-F314 HydrophobicContact CE1-CG 4.2Å; F239-F314 HydrophobicContact CE2-CD1 4.06Å; F239-F314 HydrophobicContact CE2-CE1 4.05Å; F239-F314 HydrophobicContact CZ-CB 4.37Å; F239-F314 AromaticContact CZ-CD1 3.53Å; F239-F314 HydrophobicContact CZ-CD1 3.53Å; F239-F314 AromaticContact CZ-CD2 4Å; F239-F314 HydrophobicContact CZ-CD2 4Å; F239-F314 AromaticContact CZ-CE1 3.66Å; F239-F314 HydrophobicContact CZ-CE1 3.66Å; F239-F314 HydrophobicContact CZ-CE2 4.1Å; F239-F314 AromaticContact CZ-CG 3.7Å; F239-F314 HydrophobicContact CZ-CG 3.7Å; F239-F314 AromaticContact CZ-CZ 3.93Å; F239-F314 HydrophobicContact CZ-CZ 3.93Å
240F98.7Very high91.2Very high0 Ų040.3 Ų40.30%022%0.22CC..EExtended strand (participates in β ladder)trans-158.1161.9-174.555.3-86.7000111.4L211 P214 D215 F216 E242 R257 A259 K281L211-F240 HydrophobicContact CD2-CE1 4.25Å; L211-F240 HydrophobicContact CD2-CE2 3.9Å; L211-F240 HydrophobicContact CD2-CZ 3.63Å; P214-F240 HydrophobicContact CB-CB 4.44Å; P214-F240 HydrophobicContact CB-CD2 3.68Å; P214-F240 HydrophobicContact CB-CE2 4.23Å; P214-F240 HydrophobicContact CB-CG 4.32Å; D215-F240 VanDerWaalsContact O-CA 3.23Å; D215-F240 WeakPolarHBondContact O-CA 3.17Å; D215-F240 VanDerWaalsContact O-CB 3.22Å; D215-F240 WeakPolarHBondContact O-CB 3.3Å; F216-F240 HydrophobicContact CD1-CB 3.81Å; F216-F240 HydrophobicContact CD1-CD1 4.21Å; F216-F240 HydrophobicContact CD1-CG 4.15Å; F216-F240 HydrophobicContact CE1-CB 4.39Å; F216-F240 HydrophobicContact CE1-CD1 4.23Å; F216-F240 HydrophobicContact CE1-CG 4.27Å; F216-F240 HydrophobicContact CG-CB 4.5Å; F240-E242 HydrophobicContact CD2-CB 3.99Å; F240-E242 HydrophobicContact CD2-CG 4.48Å; F240-E242 HydrophobicContact CE2-CB 4Å; F240-E242 HydrophobicContact CE2-CG 4.13Å; F240-R257 HydrophobicContact CD1-CB 4.33Å; F240-R257 HydrophobicContact CD2-CB 3.95Å; F240-R257 HydrophobicContact CD2-CG 4.13Å; F240-R257 HydrophobicContact CE1-CB 4.08Å; F240-R257 HydrophobicContact CE2-CB 3.69Å; F240-R257 HydrophobicContact CE2-CG 3.67Å; F240-R257 HydrophobicContact CG-CB 4.27Å; F240-R257 HydrophobicContact CZ-CB 3.75Å; F240-R257 HydrophobicContact CZ-CG 4.09Å; F240-R257 PolarHBondContact N-O 2.86Å; F240-R257 PolarHBondContact O-N 3.19Å; F240-A259 HydrophobicContact CE1-CB 3.74Å; F240-A259 HydrophobicContact CZ-CB 4.27Å; F240-K281 HydrophobicContact CZ-CD 4.32Å
241S98.1Very high90.3Very high5 Ų540 Ų404%0.03522%0.222CC..EExtended strand (participates in β ladder)trans-98141.2161.8-570000108.4P214 D215 V255 L298P214-S241 CarbonylContact C-O 3.52Å; P214-S241 WeakPolarHBondContact CA-O 3.49Å; D215-S241 PolarHBondContact N-O 2.89Å; D215-S241 PolarHBondContact O-N 2.96Å; S241-V255 WeakPolarHBondContact CA-O 3.27Å; S241-L298 PolarHBondContact OG-N 2.68Å; S241-L298 PolarHBondContact OG-O 3.09Å
242E96.9Very high89.6Confident2 Ų245.5 Ų45.51%0.00924%0.242CC..EExtended strand (participates in β ladder)trans-139.9162.5172.976.4170.6176.300111.1N212 P214 F240 A244 T254 V255 R257 K281N212-E242 PolarHBondContact N-OE2 3.03Å; N212-E242 VanDerWaalsContact N-OE2 3.11Å; N212-E242 WeakPolarHBondContact O-CB 3.38Å; P214-E242 HydrophobicContact CB-CB 4.21Å; F240-E242 HydrophobicContact CD2-CB 3.99Å; F240-E242 HydrophobicContact CD2-CG 4.48Å; F240-E242 HydrophobicContact CE2-CB 4Å; F240-E242 HydrophobicContact CE2-CG 4.13Å; E242-A244 PolarHBondContact O-N 2.8Å; E242-T254 CarbonylContact O-C 3.59Å; E242-T254 WeakPolarHBondContact O-CA 3.35Å; E242-V255 PolarHBondContact N-O 3.09Å; E242-V255 PolarHBondContact O-N 2.97Å; E242-R257 HydrophobicContact CG-CG 3.83Å; E242-R257 IonicContact OE1-CZ 3.59Å; E242-R257 VanDerWaalsContact OE1-CZ 3.23Å; E242-R257 IonicContact OE1-NE 3.79Å; E242-R257 PolarHBondContact OE1-NE 3.12Å; E242-R257 IonicContact OE1-NH2 2.8Å; E242-R257 PolarHBondContact OE1-NH2 2.97Å; E242-K281 VanDerWaalsContact OE1-CE 3.27Å; E242-K281 WeakPolarHBondContact OE1-CE 3.48Å; E242-K281 IonicContact OE1-NZ 2.76Å; E242-K281 PolarHBondContact OE1-NZ 2.91Å; E242-K281 IonicContact OE2-NZ 3.12Å; E242-K281 PolarHBondContact OE2-NZ 2.89Å
243R95.4Very high89.3Confident77 Ų7747 Ų4729%0.29125%0.249SC..EExtended strand (participates in β ladder)trans-69.7120.2170.9172.7-175.8170.2145.711.9110N212 E213 E252N212-R243 WeakPolarHBondContact ND2-CB 3.29Å; N212-R243 WeakPolarHBondContact ND2-CG 3.4Å; N212-R243 PolarHBondContact ND2-O 2.85Å; N212-R243 PolarHBondContact O-N 2.76Å; E213-R243 WeakPolarHBondContact OE2-CD 3.39Å; E213-R243 IonicContact OE2-NH1 3Å; R243-E252 IonicContact CZ-OE1 2.67Å; R243-E252 IonicContact CZ-OE2 2.76Å; R243-E252 IonicContact NH1-OE1 3.23Å; R243-E252 PolarHBondContact NH1-OE1 2.82Å; R243-E252 IonicContact NH1-OE2 3.89Å; R243-E252 PolarHBondContact NH1-OE2 2.89Å; R243-E252 IonicContact NH2-OE1 2.67Å; R243-E252 PolarHBondContact NH2-OE1 3.35Å; R243-E252 IonicContact NH2-OE2 3.63Å
244A93.7Very high89.2Confident10 Ų1047.7 Ų47.78%0.08326%0.255CS..  trans-63.6141.5177.900000111.3E242 L247 L253 V255E242-A244 PolarHBondContact O-N 2.8Å; A244-L247 HydrophobicContact CB-CB 4.23Å; A244-L247 HydrophobicContact CB-CD1 4.03Å; A244-L247 HydrophobicContact CB-CG 4.1Å; A244-L253 WeakPolarHBondContact CB-O 3.38Å; A244-L253 PolarHBondContact N-O 3.13Å; A244-V255 HydrophobicContact CB-CG1 4.04Å; A244-V255 HydrophobicContact CB-CG2 3.83Å
245L90.1Very high89.1Confident62 Ų6247.4 Ų47.433%0.32525%0.254SS..SBendtrans-105.3-19.8168.3-65.7175000111.2P208 N212 W356P208-L245 VanDerWaalsContact C-CD1 3.5Å; P208-L245 HydrophobicContact CB-CD1 3.72Å; P208-L245 WeakPolarHBondContact O-CD1 3.3Å; N212-L245 HydrophobicContact CB-CD1 4.43Å; N212-L245 HydrophobicContact CB-CG 4.45Å; N212-L245 WeakPolarHBondContact ND2-CD2 3.48Å; L245-W356 HydrophobicContact CB-CZ2 4.18Å; L245-W356 PolarHBondContact O-NE1 3.08Å
246E90Very high89.1Confident25 Ų2547.3 Ų47.312%0.11725%0.253CS..SBendtrans-96.23-169.882.2-79.4-166.500115.2R257 K347 W356 L400E246-R257 VanDerWaalsContact CD-NH2 3.34Å; E246-R257 IonicContact OE1-CZ 3.78Å; E246-R257 IonicContact OE1-NH1 3.76Å; E246-R257 PolarHBondContact OE1-NH1 2.89Å; E246-R257 IonicContact OE1-NH2 3.53Å; E246-R257 PolarHBondContact OE1-NH2 2.83Å; E246-R257 VanDerWaalsContact OE1-NH2 3.11Å; E246-R257 IonicContact OE2-CZ 2.76Å; E246-R257 IonicContact OE2-NH1 3.92Å; E246-R257 IonicContact OE2-NH2 3.96Å; E246-R257 PolarHBondContact OE2-NH2 3.07Å; E246-K347 HydrophobicContact CB-CD 3.78Å; E246-K347 HydrophobicContact CG-CD 3.88Å; E246-W356 HydrophobicContact CB-CB 3.75Å; E246-W356 HydrophobicContact CB-CD2 4.13Å; E246-W356 HydrophobicContact CB-CG 3.72Å; E246-L400 HydrophobicContact CB-CD2 4.05Å; E246-L400 HydrophobicContact CG-CD2 4.05Å
247L85.1Confident89.1Confident57 Ų5747.4 Ų47.430%0.29825%0.253SS..  trans-116.8115.4179.5-58.5179.5000108.6A244 L253 V255A244-L247 HydrophobicContact CB-CB 4.23Å; A244-L247 HydrophobicContact CB-CD1 4.03Å; A244-L247 HydrophobicContact CB-CG 4.1Å; L247-L253 HydrophobicContact CB-CD2 4.47Å; L247-L253 HydrophobicContact CD1-CD2 3.65Å; L247-L253 HydrophobicContact CD1-CG 4.29Å; L247-V255 HydrophobicContact CD1-CG1 3.72Å
248D72.9Confident89.1Confident157 Ų15747.4 Ų47.484%0.8425%0.254SS*.  trans-85.4110.1177.1-159.69.8000107.8
249C69.1Low89.1Confident67 Ų6747.4 Ų47.445%0.45325%0.254SS..  trans-149.5144.9-170.8-72.10000109.4T251C249-T251 WeakPolarHBondContact CB-O 3.34Å; C249-T251 PolarHBondContact O-N 2.91Å; C249-T251 VanDerWaalsContact O-N 3.15Å
250D64.6Low89.1Confident181 Ų18148 Ų4897%0.96826%0.256SS*.SBendtrans-65.9-15.2178.2-58.5-55.6000113.5
251T71.1Confident89Confident108 Ų10848 Ų4866%0.66326%0.256SS*.SBendtrans-121.7148.117554.70000111.3C249 L253C249-T251 WeakPolarHBondContact CB-O 3.34Å; C249-T251 PolarHBondContact O-N 2.91Å; C249-T251 VanDerWaalsContact O-N 3.15Å; T251-L253 PolarHBondContact O-N 3.36Å; T251-L253 VanDerWaalsContact O-N 3.08Å
252E75.8Confident89Confident138 Ų13847.9 Ų47.965%0.64526%0.255SS*.  trans-69.6104.8-178.6-53.2-169.4153.800110.5R243R243-E252 IonicContact CZ-OE1 2.67Å; R243-E252 IonicContact CZ-OE2 2.76Å; R243-E252 IonicContact NH1-OE1 3.23Å; R243-E252 PolarHBondContact NH1-OE1 2.82Å; R243-E252 IonicContact NH1-OE2 3.89Å; R243-E252 PolarHBondContact NH1-OE2 2.89Å; R243-E252 IonicContact NH2-OE1 2.67Å; R243-E252 PolarHBondContact NH2-OE1 3.35Å; R243-E252 IonicContact NH2-OE2 3.63Å
253L87.8Confident89Confident56 Ų5649.7 Ų49.729%0.29326%0.263SS..  trans-93.6111.8-170.5-177.155.2000112.5A244 L247 T251A244-L253 WeakPolarHBondContact CB-O 3.38Å; A244-L253 PolarHBondContact N-O 3.13Å; L247-L253 HydrophobicContact CB-CD2 4.47Å; L247-L253 HydrophobicContact CD1-CD2 3.65Å; L247-L253 HydrophobicContact CD1-CG 4.29Å; T251-L253 PolarHBondContact O-N 3.36Å; T251-L253 VanDerWaalsContact O-N 3.08Å
254T93.1Very high88.9Confident48 Ų4848.1 Ų48.129%0.29427%0.271SS..EExtended strand (participates in β ladder)trans-65.4144.3166.5-56.10000111.1E242 N296E242-T254 CarbonylContact O-C 3.59Å; E242-T254 WeakPolarHBondContact O-CA 3.35Å; T254-N296 VanDerWaalsContact O-CB 3.26Å; T254-N296 WeakPolarHBondContact O-CB 3.39Å
255V95.6Very high89Confident0 Ų047.8 Ų47.80%027%0.268CS..EExtended strand (participates in β ladder)trans-137.7144.9171.1-67.50000112.1S241 E242 A244 L247 R257 N296S241-V255 WeakPolarHBondContact CA-O 3.27Å; E242-V255 PolarHBondContact N-O 3.09Å; E242-V255 PolarHBondContact O-N 2.97Å; A244-V255 HydrophobicContact CB-CG1 4.04Å; A244-V255 HydrophobicContact CB-CG2 3.83Å; L247-V255 HydrophobicContact CD1-CG1 3.72Å; V255-R257 VanDerWaalsContact CG2-CZ 3.49Å; V255-N296 CarbonylContact C-O 3.57Å
256A98Very high89.3Confident0 Ų046.5 Ų46.50%026%0.261CS..EExtended strand (participates in β ladder)trans-75.7142.8171.600000111.6L284 N296 L298 F318A256-L284 HydrophobicContact CB-CB 4.35Å; A256-L284 WeakPolarHBondContact CB-O 3.44Å; A256-L284 PolarHBondContact O-N 2.85Å; A256-N296 PolarHBondContact N-O 3.25Å; A256-L298 HydrophobicContact CB-CB 3.81Å; A256-F318 HydrophobicContact CB-CD1 4.18Å; A256-F318 HydrophobicContact CB-CE1 3.68Å
257R98.4Very high89.5Confident1 Ų145.3 Ų45.30%0.00426%0.255CS..EExtended strand (participates in β ladder)trans-126.8149.1-178.2-63.4-61.3-162.4-151-7.6111.5F240 E242 E246 V255 A282F240-R257 HydrophobicContact CD1-CB 4.33Å; F240-R257 HydrophobicContact CD2-CB 3.95Å; F240-R257 HydrophobicContact CD2-CG 4.13Å; F240-R257 HydrophobicContact CE1-CB 4.08Å; F240-R257 HydrophobicContact CE2-CB 3.69Å; F240-R257 HydrophobicContact CE2-CG 3.67Å; F240-R257 HydrophobicContact CG-CB 4.27Å; F240-R257 HydrophobicContact CZ-CB 3.75Å; F240-R257 HydrophobicContact CZ-CG 4.09Å; F240-R257 PolarHBondContact N-O 2.86Å; F240-R257 PolarHBondContact O-N 3.19Å; E242-R257 HydrophobicContact CG-CG 3.83Å; E242-R257 IonicContact OE1-CZ 3.59Å; E242-R257 VanDerWaalsContact OE1-CZ 3.23Å; E242-R257 IonicContact OE1-NE 3.79Å; E242-R257 PolarHBondContact OE1-NE 3.12Å; E242-R257 IonicContact OE1-NH2 2.8Å; E242-R257 PolarHBondContact OE1-NH2 2.97Å; E246-R257 VanDerWaalsContact CD-NH2 3.34Å; E246-R257 IonicContact OE1-CZ 3.78Å; E246-R257 IonicContact OE1-NH1 3.76Å; E246-R257 PolarHBondContact OE1-NH1 2.89Å; E246-R257 IonicContact OE1-NH2 3.53Å; E246-R257 PolarHBondContact OE1-NH2 2.83Å; E246-R257 VanDerWaalsContact OE1-NH2 3.11Å; E246-R257 IonicContact OE2-CZ 2.76Å; E246-R257 IonicContact OE2-NH1 3.92Å; E246-R257 IonicContact OE2-NH2 3.96Å; E246-R257 PolarHBondContact OE2-NH2 3.07Å; V255-R257 VanDerWaalsContact CG2-CZ 3.49Å; R257-A282 WeakPolarHBondContact CA-O 3.16Å; R257-A282 WeakPolarHBondContact CD-O 3.34Å
258V98.8Very high90Very high1 Ų142.7 Ų42.71%0.00624%0.242CC..EExtended strand (participates in β ladder)trans-115.3131.5153.957.10000107.4Y237 F238 F239 K281 A282 L284 V338 F342Y237-V258 HydrophobicContact CD1-CG2 3.65Å; Y237-V258 HydrophobicContact CE1-CG2 4.21Å; F238-V258 WeakPolarHBondContact O-CA 3.38Å; F239-V258 HydrophobicContact CD1-CB 4.02Å; F239-V258 HydrophobicContact CD1-CG2 4Å; F239-V258 HydrophobicContact CE1-CB 3.84Å; F239-V258 HydrophobicContact CE1-CG2 3.47Å; F239-V258 VanDerWaalsContact CE1-CG2 3.47Å; F239-V258 HydrophobicContact CZ-CG2 3.93Å; V258-K281 CarbonylContact O-C 3.5Å; V258-K281 WeakPolarHBondContact O-CA 3.31Å; V258-A282 HydrophobicContact CG1-CB 4.31Å; V258-A282 PolarHBondContact N-O 2.99Å; V258-A282 PolarHBondContact O-N 3.28Å; V258-L284 HydrophobicContact CB-CD1 4.47Å; V258-L284 HydrophobicContact CG1-CB 4.46Å; V258-L284 HydrophobicContact CG1-CD1 4.22Å; V258-V338 HydrophobicContact CG1-CG1 4.2Å; V258-V338 HydrophobicContact CG2-CG1 4.21Å; V258-F342 HydrophobicContact CG1-CE2 4.39Å; V258-F342 HydrophobicContact CG1-CZ 4.29Å
259A98.8Very high91Very high0 Ų039.5 Ų39.50%023%0.229CC..EExtended strand (participates in β ladder)trans-124.1161.7172.800000110.5Y237 F238 F240 F279 Q280 K281Y237-A259 CarbonylContact C-O 3.51Å; Y237-A259 VanDerWaalsContact CA-O 3.3Å; Y237-A259 WeakPolarHBondContact CA-O 3.33Å; F238-A259 PolarHBondContact N-O 3.49Å; F238-A259 PolarHBondContact O-N 2.77Å; F240-A259 HydrophobicContact CE1-CB 3.74Å; F240-A259 HydrophobicContact CZ-CB 4.27Å; A259-F279 HydrophobicContact CB-CE2 3.78Å; A259-F279 HydrophobicContact CB-CZ 4.25Å; A259-Q280 CarbonylContact C-O 3.43Å; A259-Q280 WeakPolarHBondContact CA-O 3.24Å; A259-Q280 WeakPolarHBondContact CB-O 3.49Å; A259-K281 HydrophobicContact CB-CB 3.76Å
260R98.3Very high92.2Very high12 Ų1244.9 Ų44.95%0.04524%0.239CC..EExtended strand (participates in β ladder)trans-143156.3176.669.4-178.6-168.11624.6112.5I236 Y237 F279 Q280 F342I236-R260 VanDerWaalsContact O-CA 3.28Å; I236-R260 WeakPolarHBondContact O-CA 3.46Å; Y237-R260 HydrophobicContact CD1-CB 4.07Å; Y237-R260 HydrophobicContact CE1-CB 3.93Å; Y237-R260 HydrophobicContact CE2-CB 4.46Å; Y237-R260 HydrophobicContact CG-CB 4.4Å; R260-F279 WeakPolarHBondContact O-CA 3.28Å; R260-Q280 HydrophobicContact CG-CB 4.47Å; R260-Q280 PolarHBondContact N-O 3.21Å; R260-Q280 PolarHBondContact O-N 2.79Å; R260-Q280 VanDerWaalsContact O-N 3.17Å; R260-F342 HydrophobicContact CG-CD1 4.31Å; R260-F342 HydrophobicContact CG-CD2 4.43Å; R260-F342 HydrophobicContact CG-CE1 4.15Å; R260-F342 HydrophobicContact CG-CE2 4.27Å; R260-F342 HydrophobicContact CG-CG 4.45Å; R260-F342 HydrophobicContact CG-CZ 4.12Å; R260-F342 VanDerWaalsContact CZ-CB 3.41Å
261V98.6Very high93.7Very high0 Ų037.2 Ų37.20%020%0.199CC..EExtended strand (participates in β ladder)trans-135.5157.3162.2-59.60000109Y177 K235 I236 F238 W276 F279Y177-V261 HydrophobicContact CE1-CG2 4.4Å; K235-V261 CarbonylContact C-O 3.58Å; K235-V261 WeakPolarHBondContact CA-O 3.2Å; I236-V261 HydrophobicContact CB-CG2 4.01Å; I236-V261 PolarHBondContact N-O 3.44Å; I236-V261 PolarHBondContact O-N 2.93Å; F238-V261 HydrophobicContact CE2-CG2 4.12Å; V261-W276 HydrophobicContact CB-CD2 4.29Å; V261-W276 HydrophobicContact CB-CE3 4.06Å; V261-W276 HydrophobicContact CB-CZ3 4.33Å; V261-W276 HydrophobicContact CG1-CB 4.32Å; V261-W276 HydrophobicContact CG1-CD2 3.83Å; V261-W276 HydrophobicContact CG1-CE3 4.1Å; V261-W276 HydrophobicContact CG1-CG 3.91Å; V261-W276 HydrophobicContact CG2-CE3 4.35Å; V261-W276 HydrophobicContact CG2-CH2 4.23Å; V261-W276 HydrophobicContact CG2-CZ2 4.5Å; V261-W276 HydrophobicContact CG2-CZ3 4.17Å; V261-F279 HydrophobicContact CG1-CB 4.14Å; V261-F279 HydrophobicContact CG1-CD2 4.1Å
262C97.8Very high94.9Very high3 Ų332.4 Ų32.42%0.0217%0.169CC..EExtended strand (participates in β ladder)trans-84144.6171-55.90000110.3D265 T278 C371C262-D265 WeakPolarHBondContact O-CB 3.42Å; C262-D265 PolarHBondContact O-N 3.41Å; C262-T278 HydrophobicContact CB-CG2 3.85Å; C262-T278 PolarHBondContact N-OG1 2.78Å; C262-C371 HydrophobicContact CB-CB 3.87Å; C262-C371 WeakPolarHBondContact CB-SG 3.43Å; C262-C371 WeakPolarHBondContact SG-CA 3.11Å; C262-C371 WeakPolarHBondContact SG-CB 3.36Å; C262-C371 PolarHBondContact SG-N 3.14Å; C262-C371 CovalentContact SG-SG 2.03Å; C262-C371 PolarHBondContact SG-SG 2.85Å
263K96.1Very high95.9Very high40 Ų4031.9 Ų31.917%0.17417%0.167CC..THydrogen-bonded Turntrans-62.2-46.8-177.1-170.4179.567.2177.30111.6V172 D173 Y177 R193 D233 D234 D265V172-K263 HydrophobicContact CG1-CD 3.76Å; D173-K263 WeakPolarHBondContact OD2-CD 3.16Å; D173-K263 WeakPolarHBondContact OD2-CE 3.42Å; D173-K263 IonicContact OD2-NZ 3.72Å; D173-K263 PolarHBondContact OD2-NZ 3.5Å; Y177-K263 WeakPolarHBondContact OH-CG 3.1Å; Y177-K263 PolarHBondContact OH-O 3.41Å; R193-K263 PolarHBondContact NH1-O 2.9Å; D233-K263 PolarHBondContact OD2-N 2.83Å; D233-K263 VanDerWaalsContact OD2-N 3.09Å; D234-K263 HydrophobicContact CB-CB 3.95Å; D234-K263 HydrophobicContact CB-CD 3.99Å; D234-K263 WeakPolarHBondContact O-CB 3.42Å; D234-K263 PolarHBondContact O-N 2.94Å; D234-K263 WeakPolarHBondContact OD2-CE 3.49Å; D234-K263 IonicContact OD2-NZ 2.71Å; D234-K263 PolarHBondContact OD2-NZ 3.42Å; K263-D265 VanDerWaalsContact C-N 3.26Å; K263-D265 PolarHBondContact O-N 3.02Å
264G94.3Very high96.2Very high45 Ų4535.2 Ų35.246%0.46418%0.179SC..THydrogen-bonded Turntrans-79.614.2-179.800000116.1D233 L266D233-G264 PolarHBondContact OD2-N 3.08Å; G264-L266 PolarHBondContact O-N 2.75Å
265D96.1Very high96.4Very high2 Ų234.6 Ų34.61%0.01117%0.172CC..  trans-67.9126.9173.7-173.3-19.2000110.5R193 M202 C262 K263 G267 W276 T277 T278R193-D265 PolarHBondContact NH1-O 2.79Å; R193-D265 PolarHBondContact NH2-O 2.88Å; M202-D265 VanDerWaalsContact CE-OD1 3.24Å; M202-D265 WeakPolarHBondContact CE-OD1 3.11Å; C262-D265 WeakPolarHBondContact O-CB 3.42Å; C262-D265 PolarHBondContact O-N 3.41Å; K263-D265 VanDerWaalsContact C-N 3.26Å; K263-D265 PolarHBondContact O-N 3.02Å; D265-G267 PolarHBondContact OD1-N 2.9Å; D265-W276 HydrophobicContact CB-CE3 3.88Å; D265-W276 HydrophobicContact CB-CZ3 3.99Å; D265-W276 WeakPolarHBondContact OD2-CA 3.41Å; D265-T277 PolarHBondContact OD1-N 3.44Å; D265-T277 PolarHBondContact OD2-N 3.46Å; D265-T278 HydrophobicContact CB-CG2 4.04Å; D265-T278 WeakPolarHBondContact OD2-CB 3.46Å; D265-T278 WeakPolarHBondContact OD2-CG2 3.36Å; D265-T278 PolarHBondContact OD2-N 2.8Å; D265-T278 PolarHBondContact OD2-OG1 3.42Å
266L95Very high96.5Very high35 Ų3534.6 Ų34.618%0.18317%0.172CC..  trans-112.71.4-177.7-51.9-173.4000112.4Y200 G264 S384 L385Y200-L266 WeakPolarHBondContact OH-CB 3.31Å; G264-L266 PolarHBondContact O-N 2.75Å; L266-S384 WeakPolarHBondContact CA-OG 3.41Å; L266-S384 WeakPolarHBondContact CB-OG 3.44Å; L266-S384 PolarHBondContact N-OG 2.9Å; L266-L385 HydrophobicContact CB-CD1 4.14Å; L266-L385 HydrophobicContact CB-CG 3.99Å; L266-L385 HydrophobicContact CD1-CD1 4.04Å
267G95.5Very high96.5Very high0 Ų034.8 Ų34.80%017%0.173CC..  trans81.8-177.4-169.200000112.9D265 K275 S384 L385D265-G267 PolarHBondContact OD1-N 2.9Å; G267-K275 VanDerWaalsContact CA-O 3.29Å; G267-K275 WeakPolarHBondContact CA-O 3.3Å; G267-S384 PolarHBondContact N-OG 3.03Å; G267-S384 CarbonylContact O-C 3.51Å; G267-S384 VanDerWaalsContact O-CB 3.32Å; G267-S384 WeakPolarHBondContact O-CB 3.4Å; G267-S384 PolarHBondContact O-OG 3.15Å; G267-L385 WeakPolarHBondContact O-CA 3.36Å; G267-L385 WeakPolarHBondContact O-CD2 2.98Å; G267-L385 PolarHBondContact O-N 3.26Å; G267-L385 VanDerWaalsContact O-N 3.14Å
268G95.7Very high96.5Very high2 Ų234.9 Ų34.92%0.02117%0.174CC..  trans-105.7154.1176.200000112.9T271 L272 Q273G268-T271 CarbonylContact C-O 3.48Å; G268-T271 VanDerWaalsContact CA-O 3.26Å; G268-T271 WeakPolarHBondContact CA-O 3.42Å; G268-L272 PolarHBondContact N-O 3.12Å; G268-Q273 WeakPolarHBondContact O-CA 3.38Å; G268-Q273 WeakPolarHBondContact O-CG 3.34Å
269T93.8Very high96.5Very high91 Ų9135 Ų3556%0.55818%0.175SC*.SBendtrans-70.6-32.1-175.1-660000113.9Q273 L385T269-Q273 WeakPolarHBondContact O-CG 3.33Å; T269-Q273 PolarHBondContact O-NE2 2.7Å; T269-L385 WeakPolarHBondContact CB-O 3.34Å; T269-L385 PolarHBondContact OG1-O 3.07Å
270R93.9Very high96.4Very high180 Ų18035.1 Ų35.168%0.67918%0.175SC*.SBendtrans-125.7-62.5-179.3-177.3171.868.3143.4-4.9111.7D389R270-D389 IonicContact CZ-OD2 2.64Å; R270-D389 IonicContact NE-OD1 2.84Å; R270-D389 IonicContact NE-OD2 3.33Å; R270-D389 PolarHBondContact NE-OD2 2.85Å; R270-D389 IonicContact NH2-OD2 3.16Å; R270-D389 PolarHBondContact NH2-OD2 3.02Å
271T96.2Very high96.5Very high20 Ų2034.7 Ų34.712%0.12317%0.174CC..THydrogen-bonded Turntrans-74.5143.9165.6-550000109.3G268 Q273 D389 L392 N393G268-T271 CarbonylContact C-O 3.48Å; G268-T271 VanDerWaalsContact CA-O 3.26Å; G268-T271 WeakPolarHBondContact CA-O 3.42Å; T271-Q273 PolarHBondContact O-N 2.85Å; T271-D389 WeakPolarHBondContact CB-OD1 3.09Å; T271-D389 PolarHBondContact N-OD1 2.79Å; T271-D389 VanDerWaalsContact N-OD1 3.11Å; T271-D389 PolarHBondContact OG1-OD1 3.36Å; T271-L392 HydrophobicContact CG2-CB 3.72Å; T271-N393 PolarHBondContact OG1-ND2 2.89Å
272L96.4Very high96.5Very high7 Ų734.7 Ų34.74%0.03717%0.174CC..THydrogen-bonded Turntrans56.738.7177.5-67165.9000115E205 W210 G268 K274 K275 T277 L392 K396E205-L272 HydrophobicContact CG-CD2 3.69Å; W210-L272 HydrophobicContact CH2-CD2 4.02Å; W210-L272 HydrophobicContact CZ2-CD2 3.95Å; G268-L272 PolarHBondContact N-O 3.12Å; L272-K274 PolarHBondContact O-N 2.86Å; L272-K275 HydrophobicContact CB-CB 3.95Å; L272-K275 HydrophobicContact CD2-CB 3.56Å; L272-K275 HydrophobicContact CD2-CG 4.3Å; L272-K275 HydrophobicContact CG-CB 4.38Å; L272-K275 PolarHBondContact O-N 2.94Å; L272-T277 HydrophobicContact CB-CG2 4.44Å; L272-L392 HydrophobicContact CD1-CB 4.39Å; L272-L392 HydrophobicContact CD1-CD2 4.46Å; L272-L392 WeakPolarHBondContact CD1-O 3.47Å; L272-K396 HydrophobicContact CD1-CB 4.2Å; L272-K396 HydrophobicContact CD2-CB 4.25Å; L272-K396 HydrophobicContact CD2-CD 4.12Å; L272-K396 HydrophobicContact CD2-CG 4.34Å; L272-K396 HydrophobicContact CG-CB 4.34Å; L272-K396 HydrophobicContact CG-CD 4.49Å
273Q95.6Very high96.4Very high126 Ų12636.4 Ų36.459%0.58918%0.18SC*.THydrogen-bonded Turntrans-58.7121.6170.9-74.1177.1-13.100111.7G268 T269 T271 K275G268-Q273 WeakPolarHBondContact O-CA 3.38Å; G268-Q273 WeakPolarHBondContact O-CG 3.34Å; T269-Q273 WeakPolarHBondContact O-CG 3.33Å; T269-Q273 PolarHBondContact O-NE2 2.7Å; T271-Q273 PolarHBondContact O-N 2.85Å; Q273-K275 PolarHBondContact O-N 2.86Å
274K93.8Very high96.5Very high127 Ų12734.7 Ų34.755%0.55217%0.172SC*.THydrogen-bonded Turntrans55.727-174.7-54.1-178-178.7179.50113.4Y200 M202 K203 L272Y200-K274 HydrophobicContact CD2-CG 4.13Å; M202-K274 VanDerWaalsContact SD-C 3.55Å; K203-K274 PolarHBondContact N-O 2.89Å; L272-K274 PolarHBondContact O-N 2.86Å
275K97Very high96.5Very high34 Ų3433.2 Ų33.215%0.14815%0.153CC..BIsolated β-bridgetrans-126.5143.2177.1-59.8-64.3-176.8124.50110M202 K203 S204 E205 G267 L272 Q273 T277M202-K275 VanDerWaalsContact CE-C 3.49Å; M202-K275 WeakPolarHBondContact CE-O 3.13Å; K203-K275 HydrophobicContact CG-CD 3.85Å; K203-K275 VanDerWaalsContact O-CA 3.26Å; K203-K275 WeakPolarHBondContact O-CA 3.38Å; K203-K275 WeakPolarHBondContact O-CD 3.46Å; S204-K275 WeakPolarHBondContact O-CD 3.35Å; S204-K275 PolarHBondContact O-NZ 2.93Å; E205-K275 HydrophobicContact CG-CB 4.47Å; E205-K275 HydrophobicContact CG-CD 4.36Å; E205-K275 HydrophobicContact CG-CG 4.28Å; E205-K275 VanDerWaalsContact OE2-CE 3.29Å; E205-K275 WeakPolarHBondContact OE2-CE 3.2Å; E205-K275 IonicContact OE2-NZ 2.72Å; E205-K275 PolarHBondContact OE2-NZ 3.39Å; G267-K275 VanDerWaalsContact CA-O 3.29Å; G267-K275 WeakPolarHBondContact CA-O 3.3Å; L272-K275 HydrophobicContact CB-CB 3.95Å; L272-K275 HydrophobicContact CD2-CB 3.56Å; L272-K275 HydrophobicContact CD2-CG 4.3Å; L272-K275 HydrophobicContact CG-CB 4.38Å; L272-K275 PolarHBondContact O-N 2.94Å; Q273-K275 PolarHBondContact O-N 2.86Å; K275-T277 PolarHBondContact O-N 2.79Å
276W98Very high96.5Very high1 Ų133.1 Ų33.10%0.00415%0.153CC..  trans-52.2125.7178.6-58.6117.5000112.1Y177 I191 R193 M202 K203 W210 V261 D265 F279Y177-W276 HydrophobicContact CD1-CH2 4.22Å; Y177-W276 AromaticContact CE1-CH2 3.84Å; Y177-W276 HydrophobicContact CE1-CH2 3.84Å; I191-W276 PolarHBondContact O-NE1 3.23Å; R193-W276 HydrophobicContact CB-CH2 3.47Å; R193-W276 VanDerWaalsContact CB-CH2 3.47Å; R193-W276 HydrophobicContact CB-CZ2 3.67Å; R193-W276 HydrophobicContact CG-CH2 4.44Å; M202-W276 HydrophobicContact CB-CD2 4.38Å; M202-W276 HydrophobicContact CB-CE3 4.31Å; M202-W276 HydrophobicContact CB-CH2 3.83Å; M202-W276 HydrophobicContact CB-CZ2 3.89Å; M202-W276 HydrophobicContact CB-CZ3 4.04Å; M202-W276 HydrophobicContact CE-CD2 4.1Å; M202-W276 HydrophobicContact CE-CE3 3.61Å; M202-W276 HydrophobicContact CE-CZ3 4.07Å; K203-W276 VanDerWaalsContact C-CD1 3.43Å; K203-W276 PolarHBondContact O-N 3.19Å; W210-W276 HydrophobicContact CH2-CB 4.43Å; W210-W276 WeakPolarHBondContact CH2-O 3.5Å; W210-W276 HydrophobicContact CZ3-CB 4.25Å; V261-W276 HydrophobicContact CB-CD2 4.29Å; V261-W276 HydrophobicContact CB-CE3 4.06Å; V261-W276 HydrophobicContact CB-CZ3 4.33Å; V261-W276 HydrophobicContact CG1-CB 4.32Å; V261-W276 HydrophobicContact CG1-CD2 3.83Å; V261-W276 HydrophobicContact CG1-CE3 4.1Å; V261-W276 HydrophobicContact CG1-CG 3.91Å; V261-W276 HydrophobicContact CG2-CE3 4.35Å; V261-W276 HydrophobicContact CG2-CH2 4.23Å; V261-W276 HydrophobicContact CG2-CZ2 4.5Å; V261-W276 HydrophobicContact CG2-CZ3 4.17Å; D265-W276 HydrophobicContact CB-CE3 3.88Å; D265-W276 HydrophobicContact CB-CZ3 3.99Å; D265-W276 WeakPolarHBondContact OD2-CA 3.41Å; W276-F279 HydrophobicContact CB-CB 3.76Å; W276-F279 HydrophobicContact CG-CB 4.43Å
277T98.1Very high96.4Very high3 Ų332 Ų322%0.01815%0.147CC..SBendtrans-87.5-16.9166.375.60000111.7D265 L272 K275 S384 L392D265-T277 PolarHBondContact OD1-N 3.44Å; D265-T277 PolarHBondContact OD2-N 3.46Å; L272-T277 HydrophobicContact CB-CG2 4.44Å; K275-T277 PolarHBondContact O-N 2.79Å; T277-S384 WeakPolarHBondContact OG1-CB 3.47Å; T277-L392 HydrophobicContact CG2-CD2 3.43Å; T277-L392 VanDerWaalsContact CG2-CD2 3.43Å
278T98.3Very high96Very high4 Ų432.6 Ų32.63%0.02515%0.151CC..SBendtrans-104.33.8-172.563.60000114.7C262 D265 Q280 S370C262-T278 HydrophobicContact CB-CG2 3.85Å; C262-T278 PolarHBondContact N-OG1 2.78Å; D265-T278 HydrophobicContact CB-CG2 4.04Å; D265-T278 WeakPolarHBondContact OD2-CB 3.46Å; D265-T278 WeakPolarHBondContact OD2-CG2 3.36Å; D265-T278 PolarHBondContact OD2-N 2.8Å; D265-T278 PolarHBondContact OD2-OG1 3.42Å; T278-Q280 PolarHBondContact O-N 3.42Å; T278-S370 WeakPolarHBondContact CG2-O 3.41Å
279F98.8Very high95.4Very high4 Ų435.8 Ų35.82%0.01817%0.171CC..  trans-69119.4179.4179.6-101.4000112.2I191 W210 L211 A259 R260 V261 W276 K281 P399I191-F279 HydrophobicContact CD1-CD2 4.46Å; I191-F279 HydrophobicContact CD1-CE2 3.67Å; I191-F279 HydrophobicContact CD1-CZ 4.41Å; W210-F279 HydrophobicContact CB-CE1 4.1Å; W210-F279 AromaticContact CD2-CD1 3.72Å; W210-F279 HydrophobicContact CD2-CD1 3.72Å; W210-F279 HydrophobicContact CD2-CE1 4.04Å; W210-F279 HydrophobicContact CE3-CB 4.16Å; W210-F279 AromaticContact CE3-CD1 3.24Å; W210-F279 HydrophobicContact CE3-CD1 3.24Å; W210-F279 AromaticContact CE3-CE1 3.73Å; W210-F279 HydrophobicContact CE3-CE1 3.73Å; W210-F279 AromaticContact CE3-CG 3.78Å; W210-F279 HydrophobicContact CE3-CG 3.78Å; W210-F279 HydrophobicContact CG-CD1 4.34Å; W210-F279 HydrophobicContact CG-CE1 4.22Å; W210-F279 HydrophobicContact CH2-CB 4.07Å; W210-F279 HydrophobicContact CH2-CD1 4.37Å; W210-F279 HydrophobicContact CZ3-CB 3.6Å; W210-F279 AromaticContact CZ3-CD1 3.62Å; W210-F279 HydrophobicContact CZ3-CD1 3.62Å; W210-F279 AromaticContact CZ3-CG 3.74Å; W210-F279 HydrophobicContact CZ3-CG 3.74Å; L211-F279 HydrophobicContact CD2-CZ 4.31Å; A259-F279 HydrophobicContact CB-CE2 3.78Å; A259-F279 HydrophobicContact CB-CZ 4.25Å; R260-F279 WeakPolarHBondContact O-CA 3.28Å; V261-F279 HydrophobicContact CG1-CB 4.14Å; V261-F279 HydrophobicContact CG1-CD2 4.1Å; W276-F279 HydrophobicContact CB-CB 3.76Å; W276-F279 HydrophobicContact CG-CB 4.43Å; F279-K281 HydrophobicContact CZ-CB 4.35Å; F279-K281 HydrophobicContact CZ-CD 4.48Å; F279-P399 HydrophobicContact CD1-CB 3.86Å; F279-P399 HydrophobicContact CE1-CB 3.9Å
280Q98.3Very high94.9Very high2 Ų237.2 Ų37.21%0.00917%0.171CC..EExtended strand (participates in β ladder)trans-135145.5172-60.9177.1-3500109.4A259 R260 T278 F342 P368 G369 P399 M401A259-Q280 CarbonylContact C-O 3.43Å; A259-Q280 WeakPolarHBondContact CA-O 3.24Å; A259-Q280 WeakPolarHBondContact CB-O 3.49Å; R260-Q280 HydrophobicContact CG-CB 4.47Å; R260-Q280 PolarHBondContact N-O 3.21Å; R260-Q280 PolarHBondContact O-N 2.79Å; R260-Q280 VanDerWaalsContact O-N 3.17Å; T278-Q280 PolarHBondContact O-N 3.42Å; Q280-F342 HydrophobicContact CB-CD1 3.59Å; Q280-F342 HydrophobicContact CB-CE1 3.7Å; Q280-P368 PolarHBondContact NE2-O 2.67Å; Q280-G369 PolarHBondContact NE2-O 2.8Å; Q280-G369 PolarHBondContact OE1-O 3.49Å; Q280-P399 CarbonylContact C-O 3.56Å; Q280-P399 WeakPolarHBondContact CA-O 3.33Å; Q280-M401 HydrophobicContact CB-SD 4.47Å
281K98.6Very high94.1Very high3 Ų334.4 Ų34.41%0.01316%0.161CC..EExtended strand (participates in β ladder)trans-130.6147.1171.571.2177.8177.2-173.70112.5A209 W210 F240 E242 V258 A259 F279 P399 L400 M401A209-K281 WeakPolarHBondContact O-CE 3.36Å; A209-K281 PolarHBondContact O-NZ 2.94Å; W210-K281 WeakPolarHBondContact O-CD 2.95Å; W210-K281 WeakPolarHBondContact O-CE 3.35Å; W210-K281 PolarHBondContact O-NZ 3.41Å; F240-K281 HydrophobicContact CZ-CD 4.32Å; E242-K281 VanDerWaalsContact OE1-CE 3.27Å; E242-K281 WeakPolarHBondContact OE1-CE 3.48Å; E242-K281 IonicContact OE1-NZ 2.76Å; E242-K281 PolarHBondContact OE1-NZ 2.91Å; E242-K281 IonicContact OE2-NZ 3.12Å; E242-K281 PolarHBondContact OE2-NZ 2.89Å; V258-K281 CarbonylContact O-C 3.5Å; V258-K281 WeakPolarHBondContact O-CA 3.31Å; A259-K281 HydrophobicContact CB-CB 3.76Å; F279-K281 HydrophobicContact CZ-CB 4.35Å; F279-K281 HydrophobicContact CZ-CD 4.48Å; K281-P399 PolarHBondContact N-O 3.09Å; K281-L400 HydrophobicContact CG-CD1 4.11Å; K281-L400 WeakPolarHBondContact O-CA 3.29Å; K281-M401 PolarHBondContact O-N 2.91Å
282A98.4Very high93.5Very high0 Ų042 Ų420%020%0.195CC..EExtended strand (participates in β ladder)trans-132.415617700000110.6R257 V258 V341 F342 M401R257-A282 WeakPolarHBondContact CA-O 3.16Å; R257-A282 WeakPolarHBondContact CD-O 3.34Å; V258-A282 HydrophobicContact CG1-CB 4.31Å; V258-A282 PolarHBondContact N-O 2.99Å; V258-A282 PolarHBondContact O-N 3.28Å; A282-V341 HydrophobicContact CB-CG1 3.55Å; A282-F342 HydrophobicContact CB-CE1 4.09Å; A282-F342 HydrophobicContact CB-CZ 4.09Å; A282-M401 HydrophobicContact CB-CB 4.12Å; A282-M401 HydrophobicContact CB-CG 4.14Å
283R97.4Very high92.9Very high39 Ų3943.3 Ų43.315%0.14720%0.203CC..EExtended strand (participates in β ladder)trans-71.7130.6172-170.9176.4178-169.3-1.3109.9E285 N296 K404 A405R283-E285 IonicContact CZ-OE1 3.33Å; R283-E285 IonicContact NE-OE1 3.11Å; R283-E285 IonicContact NH1-OE1 2.85Å; R283-E285 PolarHBondContact NH1-OE1 2.87Å; R283-E285 IonicContact NH2-OE1 2.89Å; R283-N296 PolarHBondContact NH2-OD1 3.38Å; R283-K404 HydrophobicContact CB-CB 4.09Å; R283-A405 PolarHBondContact O-N 2.75Å
284L97.1Very high92.5Very high3 Ų339.3 Ų39.32%0.01619%0.189CC..EExtended strand (participates in β ladder)trans-101.5101.2171.8-170.571.2000107.1F239 A256 V258 L298 F318 Y333 A405F239-L284 HydrophobicContact CD1-CD2 4.12Å; F239-L284 HydrophobicContact CE1-CD2 4.48Å; A256-L284 HydrophobicContact CB-CB 4.35Å; A256-L284 WeakPolarHBondContact CB-O 3.44Å; A256-L284 PolarHBondContact O-N 2.85Å; V258-L284 HydrophobicContact CB-CD1 4.47Å; V258-L284 HydrophobicContact CG1-CB 4.46Å; V258-L284 HydrophobicContact CG1-CD1 4.22Å; L284-L298 HydrophobicContact CD2-CD2 4.41Å; L284-F318 HydrophobicContact CD2-CE1 4.43Å; L284-F318 HydrophobicContact CD2-CZ 3.97Å; L284-F318 HydrophobicContact CG-CZ 4.2Å; L284-Y333 HydrophobicContact CD1-CD1 3.51Å; L284-Y333 HydrophobicContact CD1-CD2 3.82Å; L284-Y333 HydrophobicContact CD1-CE1 3.48Å; L284-Y333 VanDerWaalsContact CD1-CE1 3.48Å; L284-Y333 HydrophobicContact CD1-CE2 3.84Å; L284-Y333 HydrophobicContact CD1-CG 3.68Å; L284-Y333 HydrophobicContact CD2-CE2 4.18Å; L284-Y333 HydrophobicContact CG-CD1 4.44Å; L284-Y333 HydrophobicContact CG-CD2 4.37Å; L284-Y333 HydrophobicContact CG-CE1 3.96Å; L284-Y333 HydrophobicContact CG-CE2 3.93Å; L284-A405 HydrophobicContact CD1-CB 3.95Å
285E95.3Very high92.5Very high15 Ų1533.4 Ų33.47%0.0716%0.163CC..EExtended strand (participates in β ladder)trans-103.3120.3-172.7-167.2-176.2-87.500110.8R283 S287 Y333 K404 A405 L406 G407R283-E285 IonicContact CZ-OE1 3.33Å; R283-E285 IonicContact NE-OE1 3.11Å; R283-E285 IonicContact NH1-OE1 2.85Å; R283-E285 PolarHBondContact NH1-OE1 2.87Å; R283-E285 IonicContact NH2-OE1 2.89Å; E285-S287 PolarHBondContact OE2-OG 2.94Å; E285-Y333 PolarHBondContact O-OH 3.44Å; E285-K404 HydrophobicContact CB-CD 4.16Å; E285-K404 WeakPolarHBondContact OE1-CD 3.48Å; E285-K404 IonicContact OE1-NZ 2.64Å; E285-K404 PolarHBondContact OE1-NZ 2.85Å; E285-K404 IonicContact OE2-NZ 2.77Å; E285-K404 PolarHBondContact OE2-NZ 3.04Å; E285-A405 PolarHBondContact N-O 2.8Å; E285-L406 HydrophobicContact CB-CD2 4.37Å; E285-L406 WeakPolarHBondContact OE2-CD2 3.26Å; E285-G407 PolarHBondContact O-N 2.78Å
286C95.6Very high92.2Very high0 Ų032.5 Ų32.50%016%0.16CC..EExtended strand (participates in β ladder)trans-100.5114.1168.4-174.10000107.3S294 F295 F318 C331 Y333 G407C286-S294 CarbonylContact O-C 3.53Å; C286-S294 WeakPolarHBondContact O-CA 3.4Å; C286-F295 HydrophobicContact CB-CB 4.17Å; C286-F295 PolarHBondContact O-N 3.07Å; C286-F318 HydrophobicContact CB-CB 4.41Å; C286-F318 HydrophobicContact CB-CD1 3.85Å; C286-F318 HydrophobicContact CB-CD2 3.66Å; C286-F318 HydrophobicContact CB-CE1 3.91Å; C286-F318 HydrophobicContact CB-CE2 3.77Å; C286-F318 HydrophobicContact CB-CG 3.73Å; C286-F318 HydrophobicContact CB-CZ 3.88Å; C286-C331 WeakPolarHBondContact CA-SG 3.48Å; C286-C331 HydrophobicContact CB-CB 3.79Å; C286-C331 WeakPolarHBondContact CB-SG 3.28Å; C286-C331 WeakPolarHBondContact SG-CB 3.36Å; C286-C331 CovalentContact SG-SG 2.04Å; C286-C331 PolarHBondContact SG-SG 3.31Å; C286-Y333 WeakPolarHBondContact CA-OH 3.35Å; C286-Y333 WeakPolarHBondContact CB-OH 3.3Å; C286-Y333 PolarHBondContact N-OH 2.9Å; C286-G407 WeakPolarHBondContact CA-O 3.21Å
287S92.3Very high92Very high10 Ų1034.9 Ų34.97%0.0717%0.173CC..EExtended strand (participates in β ladder)trans-150.9157.5-171.562.10000115.4E285 V293 G407 P409E285-S287 PolarHBondContact OE2-OG 2.94Å; S287-V293 WeakPolarHBondContact CA-O 3.49Å; S287-V293 WeakPolarHBondContact CB-O 3.19Å; S287-G407 PolarHBondContact N-O 2.74Å; S287-P409 WeakPolarHBondContact O-CD 3.28Å
288L86.5Confident92Very high14 Ų1434.7 Ų34.77%0.07317%0.172CC..EExtended strand (participates in β ladder)trans-12286.2169.3-70.2172.1000108.3L21 W23 E290 R291 H292 V293 P409 L412L21-L288 HydrophobicContact CD2-CD1 3.87Å; L21-L288 HydrophobicContact CD2-CD2 4.11Å; W23-L288 HydrophobicContact CZ2-CD1 3.79Å; L288-E290 PolarHBondContact O-N 2.82Å; L288-R291 CarbonylContact O-C 3.58Å; L288-R291 PolarHBondContact O-N 2.9Å; L288-H292 PolarHBondContact O-N 2.69Å; L288-H292 VanDerWaalsContact O-N 3.15Å; L288-V293 PolarHBondContact N-O 2.91Å; L288-V293 PolarHBondContact O-N 3Å; L288-P409 HydrophobicContact CD1-CG 4.29Å; L288-P409 HydrophobicContact CD2-CG 4.3Å; L288-P409 HydrophobicContact CG-CG 3.95Å; L288-L412 HydrophobicContact CD1-CD2 4.2Å
289P84.2Confident91.9Very high69 Ų6939.4 Ų39.445%0.44819%0.189SC..G310 helixtrans-54.9-35.3-177.5-27.436000113.5R291 H292P289-R291 PolarHBondContact O-N 2.87Å; P289-R291 VanDerWaalsContact O-N 3.11Å; P289-H292 PolarHBondContact O-N 3.01Å; P289-H292 VanDerWaalsContact O-N 3.1Å
290E83.3Confident91.9Very high120 Ų12039.5 Ų39.556%0.56119%0.191SC*.G310 helixtrans-66.8-11.4-179.1-54.372.8-155.100113.3L288 R408L288-E290 PolarHBondContact O-N 2.82Å; E290-R408 IonicContact OE1-CZ 3.21Å; E290-R408 VanDerWaalsContact OE1-CZ 3.23Å; E290-R408 IonicContact OE1-NH1 2.9Å; E290-R408 PolarHBondContact OE1-NH1 2.8Å; E290-R408 IonicContact OE1-NH2 3.82Å; E290-R408 PolarHBondContact OE1-NH2 2.9Å; E290-R408 IonicContact OE2-CZ 2.78Å; E290-R408 IonicContact OE2-NH1 3.89Å; E290-R408 PolarHBondContact OE2-NH1 3.19Å
291R77.9Confident91.9Very high121 Ų12140.9 Ų40.946%0.45720%0.199SC..G310 helixtrans-129.716176.7-63.6-178.6178.9-150.74.1112W23 L288 P289 V293W23-R291 HydrophobicContact CZ2-CG 4.48Å; L288-R291 CarbonylContact O-C 3.58Å; L288-R291 PolarHBondContact O-N 2.9Å; P289-R291 PolarHBondContact O-N 2.87Å; P289-R291 VanDerWaalsContact O-N 3.11Å; R291-V293 PolarHBondContact O-N 3.31Å; R291-V293 VanDerWaalsContact O-N 3.11Å
292H82.6Confident91.9Very high181 Ų18142.7 Ų42.784%0.83821%0.207SC*.THydrogen-bonded Turntrans5326.6176.5-57-71.3000116.5L288 P289L288-H292 PolarHBondContact O-N 2.69Å; L288-H292 VanDerWaalsContact O-N 3.15Å; P289-H292 PolarHBondContact O-N 3.01Å; P289-H292 VanDerWaalsContact O-N 3.1Å
293V83.1Confident91.8Very high34 Ų3444.6 Ų44.621%0.20622%0.219CC..EExtended strand (participates in β ladder)trans-117.5140.3-176.3164.90000113.4S287 L288 R291 F295 W322S287-V293 WeakPolarHBondContact CA-O 3.49Å; S287-V293 WeakPolarHBondContact CB-O 3.19Å; L288-V293 PolarHBondContact N-O 2.91Å; L288-V293 PolarHBondContact O-N 3Å; R291-V293 PolarHBondContact O-N 3.31Å; R291-V293 VanDerWaalsContact O-N 3.11Å; V293-F295 HydrophobicContact CG1-CE1 4.23Å; V293-F295 HydrophobicContact CG1-CE2 3.99Å; V293-F295 HydrophobicContact CG1-CZ 3.72Å; V293-W322 HydrophobicContact CB-CE3 4.43Å; V293-W322 HydrophobicContact CB-CZ3 3.81Å; V293-W322 HydrophobicContact CG1-CE3 4.21Å; V293-W322 HydrophobicContact CG1-CZ3 4.03Å; V293-W322 HydrophobicContact CG2-CE3 3.82Å; V293-W322 HydrophobicContact CG2-CH2 3.8Å; V293-W322 HydrophobicContact CG2-CZ3 3.26Å
294S88.4Confident91.8Very high42 Ų4243 Ų4329%0.29421%0.213SC..EExtended strand (participates in β ladder)trans-129.2141.917859.90000110.7C286 N296C286-S294 CarbonylContact O-C 3.53Å; C286-S294 WeakPolarHBondContact O-CA 3.4Å; S294-N296 PolarHBondContact OG-ND2 3.31Å
295F92.5Very high91.6Very high2 Ų246.7 Ų46.71%0.00924%0.237CC..EExtended strand (participates in β ladder)trans-107102179.6-52.9-92.1000107.6C286 V293 F318 A320 V327 A329 P409 L412C286-F295 HydrophobicContact CB-CB 4.17Å; C286-F295 PolarHBondContact O-N 3.07Å; V293-F295 HydrophobicContact CG1-CE1 4.23Å; V293-F295 HydrophobicContact CG1-CE2 3.99Å; V293-F295 HydrophobicContact CG1-CZ 3.72Å; F295-F318 HydrophobicContact CB-CB 3.48Å; F295-F318 VanDerWaalsContact CB-CB 3.48Å; F295-F318 HydrophobicContact CB-CG 4.3Å; F295-F318 WeakPolarHBondContact O-CD1 3.28Å; F295-A320 HydrophobicContact CB-CB 4.48Å; F295-A320 HydrophobicContact CD1-CB 3.46Å; F295-A320 VanDerWaalsContact CD1-CB 3.46Å; F295-A320 HydrophobicContact CE1-CB 3.96Å; F295-A320 HydrophobicContact CG-CB 4.27Å; F295-V327 HydrophobicContact CE1-CB 4.28Å; F295-V327 HydrophobicContact CE1-CG1 3.94Å; F295-A329 HydrophobicContact CB-CB 4.32Å; F295-A329 HydrophobicContact CD1-CB 3.71Å; F295-A329 HydrophobicContact CD2-CB 3.83Å; F295-A329 HydrophobicContact CE1-CB 3.98Å; F295-A329 HydrophobicContact CE2-CB 4.1Å; F295-A329 HydrophobicContact CG-CB 3.66Å; F295-A329 HydrophobicContact CZ-CB 4.19Å; F295-P409 HydrophobicContact CD2-CG 4.14Å; F295-P409 HydrophobicContact CE2-CG 3.87Å; F295-L412 HydrophobicContact CE1-CD1 3.59Å; F295-L412 HydrophobicContact CE2-CD1 4.14Å; F295-L412 HydrophobicContact CZ-CD1 3.31Å
296N90.8Very high91.5Very high16 Ų1646.8 Ų46.89%0.08624%0.243CC..  trans-100.2-16.8-165.8-66.9-59.8000114.3T254 V255 A256 R283 S294T254-N296 VanDerWaalsContact O-CB 3.26Å; T254-N296 WeakPolarHBondContact O-CB 3.39Å; V255-N296 CarbonylContact C-O 3.57Å; A256-N296 PolarHBondContact N-O 3.25Å; R283-N296 PolarHBondContact NH2-OD1 3.38Å; S294-N296 PolarHBondContact OG-ND2 3.31Å
297N95Very high91.2Very high50 Ų5053.4 Ų53.427%0.26729%0.286SS..EExtended strand (participates in β ladder)trans-97.6100.4-179.1-53.9-76.6000110F318 H319N297-F318 CarbonylContact O-C 3.51Å; N297-F318 VanDerWaalsContact O-CA 3.23Å; N297-F318 WeakPolarHBondContact O-CA 3.19Å; N297-H319 HydrophobicContact CB-CB 4.36Å; N297-H319 PolarHBondContact N-O 2.79Å; N297-H319 PolarHBondContact ND2-O 2.86Å; N297-H319 VanDerWaalsContact ND2-O 3.16Å; N297-H319 PolarHBondContact O-N 3.38Å
298L97.9Very high91.2Very high0 Ų056 Ų560%030%0.299CS..EExtended strand (participates in β ladder)trans-72.6139.5174-172.872.3000110.4V217 F239 S241 A256 L284 V301 F318V217-L298 HydrophobicContact CB-CD2 4.24Å; V217-L298 HydrophobicContact CB-CG 4.45Å; V217-L298 HydrophobicContact CG1-CD2 4.3Å; V217-L298 HydrophobicContact CG1-CG 4.16Å; V217-L298 HydrophobicContact CG2-CB 4.45Å; V217-L298 HydrophobicContact CG2-CD2 4.35Å; V217-L298 HydrophobicContact CG2-CG 4.28Å; V217-L298 WeakPolarHBondContact CG2-O 3.46Å; F239-L298 HydrophobicContact CB-CD2 3.88Å; S241-L298 PolarHBondContact OG-N 2.68Å; S241-L298 PolarHBondContact OG-O 3.09Å; A256-L298 HydrophobicContact CB-CB 3.81Å; L284-L298 HydrophobicContact CD2-CD2 4.41Å; L298-V301 HydrophobicContact CD1-CG2 3.91Å; L298-V301 HydrophobicContact CD2-CG2 3.74Å; L298-V301 HydrophobicContact CG-CG2 4.12Å; L298-F318 HydrophobicContact CB-CD1 4.27Å; L298-F318 HydrophobicContact CB-CE1 4.26Å; L298-F318 HydrophobicContact CD1-CD1 3.96Å; L298-F318 HydrophobicContact CD1-CD2 4.21Å; L298-F318 HydrophobicContact CD1-CE1 3.57Å; L298-F318 HydrophobicContact CD1-CE2 3.81Å; L298-F318 HydrophobicContact CD1-CG 4.27Å; L298-F318 HydrophobicContact CD1-CZ 3.48Å; L298-F318 VanDerWaalsContact CD1-CZ 3.48Å; L298-F318 HydrophobicContact CG-CE1 4.48Å
299R96.6Very high91.5Very high102 Ų10257.2 Ų57.239%0.38530%0.302SS..EExtended strand (participates in β ladder)trans-128.8-28.3-173.6-63.3-59.9-160.6-165.62.8115.9D215 V217 I317 H319D215-R299 IonicContact OD2-NH1 2.79Å; V217-R299 VanDerWaalsContact CG1-C 3.45Å; R299-I317 HydrophobicContact CB-CG2 4.13Å; R299-I317 PolarHBondContact N-O 3.47Å; R299-H319 HydrophobicContact CG-CB 4.45Å; R299-H319 PolarHBondContact NE-ND1 3.45Å
300A97.7Very high92Very high7 Ų760.1 Ų60.16%0.05830%0.304CS..EExtended strand (participates in β ladder)trans-152.8149.5172.600000109.2G316 I317A300-G316 WeakPolarHBondContact O-CA 3.44Å; A300-I317 HydrophobicContact CB-CB 4.28Å; A300-I317 HydrophobicContact CB-CD1 4.06Å; A300-I317 HydrophobicContact CB-CG1 4.48Å; A300-I317 PolarHBondContact O-N 3.38Å
301V98.3Very high92.6Very high30 Ų3055.6 Ų55.618%0.18229%0.29CS..EExtended strand (participates in β ladder)trans-129.3138.41701740000109.4V217 F239 L298 Y315V217-V301 HydrophobicContact CG1-CG2 4.26Å; F239-V301 HydrophobicContact CB-CB 4.44Å; F239-V301 HydrophobicContact CB-CG2 3.77Å; F239-V301 HydrophobicContact CD1-CG1 4.43Å; F239-V301 HydrophobicContact CD1-CG2 4.17Å; F239-V301 HydrophobicContact CD2-CB 4.5Å; F239-V301 HydrophobicContact CD2-CG1 4.02Å; F239-V301 HydrophobicContact CE2-CG1 4.18Å; F239-V301 HydrophobicContact CG-CB 4.37Å; F239-V301 HydrophobicContact CG-CG1 4.16Å; F239-V301 HydrophobicContact CG-CG2 3.92Å; F239-V301 HydrophobicContact CZ-CG1 4.46Å; L298-V301 HydrophobicContact CD1-CG2 3.91Å; L298-V301 HydrophobicContact CD2-CG2 3.74Å; L298-V301 HydrophobicContact CG-CG2 4.12Å; V301-Y315 CarbonylContact C-O 3.59Å; V301-Y315 VanDerWaalsContact CA-O 3.26Å; V301-Y315 WeakPolarHBondContact CA-O 3.44Å
302F98.1Very high93.5Very high41 Ų4150.3 Ų50.318%0.1827%0.271CS..EExtended strand (participates in β ladder)trans-120.1134.3167.6-171.6-91000109.3L304 Y315 L421 A422 V423 I476F302-L304 HydrophobicContact CD1-CB 4.38Å; F302-L304 HydrophobicContact CE1-CB 4.28Å; F302-L304 HydrophobicContact CE1-CD1 4.29Å; F302-Y315 PolarHBondContact N-O 2.92Å; F302-Y315 PolarHBondContact O-N 3.35Å; F302-L421 HydrophobicContact CB-CB 4.44Å; F302-L421 HydrophobicContact CB-CD2 3.99Å; F302-L421 HydrophobicContact CB-CG 4.05Å; F302-L421 WeakPolarHBondContact CD2-O 3.48Å; F302-A422 HydrophobicContact CD2-CB 4.4Å; F302-A422 HydrophobicContact CE2-CB 4.18Å; F302-V423 HydrophobicContact CB-CG2 4.37Å; F302-V423 HydrophobicContact CD1-CB 3.65Å; F302-V423 HydrophobicContact CD1-CG2 3.67Å; F302-V423 HydrophobicContact CE1-CB 3.7Å; F302-V423 HydrophobicContact CE1-CG2 4.24Å; F302-V423 VanDerWaalsContact CE1-O 3.3Å; F302-V423 WeakPolarHBondContact CE1-O 3.26Å; F302-V423 HydrophobicContact CG-CB 4.49Å; F302-V423 HydrophobicContact CG-CG2 4.16Å; F302-V423 WeakPolarHBondContact CZ-O 3.23Å; F302-I476 HydrophobicContact CE2-CG2 4.2Å; F302-I476 HydrophobicContact CZ-CG2 4.15Å
303T97.6Very high94.2Very high40 Ų4041.9 Ų41.925%0.24523%0.232CC..EExtended strand (participates in β ladder)trans-103.5110.4177.1-57.90000109A220 P305 T312 F314A220-T303 HydrophobicContact CB-CG2 4.17Å; A220-T303 WeakPolarHBondContact CB-OG1 3.36Å; T303-P305 WeakPolarHBondContact O-CD 3.45Å; T303-T312 HydrophobicContact CG2-CG2 3.6Å; T303-F314 HydrophobicContact CG2-CD1 3.86Å; T303-F314 HydrophobicContact CG2-CE1 3.71Å; T303-F314 WeakPolarHBondContact OG1-CD1 3.46Å
304L96.8Very high94.9Very high5 Ų540.4 Ų40.43%0.02622%0.223CC..EExtended strand (participates in β ladder)trans-93.8106.7175.6-17768.1000108.7F302 T312 T313 Y315 V423 R425F302-L304 HydrophobicContact CD1-CB 4.38Å; F302-L304 HydrophobicContact CE1-CB 4.28Å; F302-L304 HydrophobicContact CE1-CD1 4.29Å; L304-T312 WeakPolarHBondContact O-CA 3.35Å; L304-T313 PolarHBondContact N-O 3.38Å; L304-T313 PolarHBondContact O-N 2.86Å; L304-Y315 HydrophobicContact CB-CD2 4.35Å; L304-Y315 HydrophobicContact CB-CE2 4.18Å; L304-Y315 HydrophobicContact CD2-CE2 3.96Å; L304-V423 HydrophobicContact CD1-CG1 4.4Å; L304-V423 HydrophobicContact CD2-CG1 3.99Å; L304-R425 HydrophobicContact CD1-CB 4.42Å
305P93.8Very high95.4Very high81 Ų8138.4 Ų38.453%0.52621%0.209SC..  trans-65.2152.9-179.927.1-34.8000111.9T303 R425T303-P305 WeakPolarHBondContact O-CD 3.45Å; P305-R425 PolarHBondContact O-NH1 2.8Å; P305-R425 PolarHBondContact O-NH2 3.49Å
306G91.6Very high95.7Very high18 Ų1838.4 Ų38.419%0.18621%0.21CC..  trans-85.5-180168.600000112.8D308 G311G306-D308 CarbonylContact C-O 3.47Å; G306-D308 VanDerWaalsContact C-O 3.28Å; G306-D308 VanDerWaalsContact CA-O 3.23Å; G306-D308 WeakPolarHBondContact CA-O 3.38Å; G306-G311 VanDerWaalsContact CA-O 3.28Å; G306-G311 WeakPolarHBondContact CA-O 3.45Å; G306-G311 PolarHBondContact N-O 3.03Å
307P89.7Confident96.1Very high139 Ų13937.6 Ų37.690%0.90321%0.206SC*.SBendtrans-62.7-31.8162.9-18.732.6000111.9
308D92.4Very high96.2Very high64 Ų6435.2 Ų35.234%0.34219%0.193SC..SBendtrans-119.2178.2162.485-27.4000109.9G306 R310 G311G306-D308 CarbonylContact C-O 3.47Å; G306-D308 VanDerWaalsContact C-O 3.28Å; G306-D308 VanDerWaalsContact CA-O 3.23Å; G306-D308 WeakPolarHBondContact CA-O 3.38Å; D308-R310 VanDerWaalsContact C-N 3.27Å; D308-R310 PolarHBondContact O-N 2.83Å; D308-R310 WeakPolarHBondContact OD1-CA 3.37Å; D308-R310 WeakPolarHBondContact OD1-CB 3.33Å; D308-R310 PolarHBondContact OD1-N 3.42Å; D308-R310 WeakPolarHBondContact OD2-CB 3.48Å; D308-R310 WeakPolarHBondContact OD2-CD 3.37Å; D308-R310 VanDerWaalsContact OD2-CG 3.22Å; D308-R310 WeakPolarHBondContact OD2-CG 3.38Å; D308-R310 IonicContact OD2-CZ 2.7Å; D308-R310 IonicContact OD2-NE 3.9Å; D308-R310 IonicContact OD2-NH1 2.6Å; D308-R310 PolarHBondContact OD2-NH1 2.73Å; D308-G311 PolarHBondContact O-N 2.76Å; D308-G311 PolarHBondContact OD1-N 3.35Å
309W93.6Very high96Very high39 Ų3936.6 Ų36.615%0.14820%0.199CC..G310 helixtrans-65.9-29.6177.770.6-104.4000112.6V222 E224 S226 G311 T312 I335 K339V222-W309 HydrophobicContact CG1-CB 4.26Å; V222-W309 HydrophobicContact CG1-CE3 4.27Å; E224-W309 HydrophobicContact CB-CD2 4.38Å; E224-W309 HydrophobicContact CB-CH2 4.46Å; E224-W309 HydrophobicContact CB-CZ2 4.26Å; E224-W309 HydrophobicContact CG-CD2 4.12Å; E224-W309 HydrophobicContact CG-CE3 3.86Å; E224-W309 HydrophobicContact CG-CH2 4.22Å; E224-W309 HydrophobicContact CG-CZ2 4.44Å; E224-W309 HydrophobicContact CG-CZ3 3.92Å; E224-W309 PolarHBondContact O-NE1 3.06Å; S226-W309 PolarHBondContact O-NE1 3.13Å; W309-G311 VanDerWaalsContact C-N 3.28Å; W309-G311 PolarHBondContact O-N 3.07Å; W309-T312 WeakPolarHBondContact O-CB 3.35Å; W309-T312 PolarHBondContact O-N 2.69Å; W309-T312 VanDerWaalsContact O-N 3.09Å; W309-T312 PolarHBondContact O-OG1 3.32Å; W309-I335 HydrophobicContact CE3-CG1 4.33Å; W309-I335 HydrophobicContact CE3-CG2 4.39Å; W309-I335 HydrophobicContact CZ3-CG1 4.29Å; W309-I335 WeakPolarHBondContact O-CG2 3.38Å; W309-K339 HydrophobicContact CH2-CD 4.02Å; W309-K339 HydrophobicContact CZ3-CD 4.24Å
310R95.1Very high95.6Very high130 Ų13032.5 Ų32.549%0.49119%0.187SC..G310 helixtrans-68-28.4-177.1-56.7175.3-176.283.80.3112.3G227 D308 T312 I335G227-R310 PolarHBondContact O-NH2 3.3Å; D308-R310 VanDerWaalsContact C-N 3.27Å; D308-R310 PolarHBondContact O-N 2.83Å; D308-R310 WeakPolarHBondContact OD1-CA 3.37Å; D308-R310 WeakPolarHBondContact OD1-CB 3.33Å; D308-R310 PolarHBondContact OD1-N 3.42Å; D308-R310 WeakPolarHBondContact OD2-CB 3.48Å; D308-R310 WeakPolarHBondContact OD2-CD 3.37Å; D308-R310 VanDerWaalsContact OD2-CG 3.22Å; D308-R310 WeakPolarHBondContact OD2-CG 3.38Å; D308-R310 IonicContact OD2-CZ 2.7Å; D308-R310 IonicContact OD2-NE 3.9Å; D308-R310 IonicContact OD2-NH1 2.6Å; D308-R310 PolarHBondContact OD2-NH1 2.73Å; R310-T312 PolarHBondContact O-N 3.41Å; R310-I335 WeakPolarHBondContact O-CG2 3.5Å
311G94.9Very high94.9Very high26 Ų2639.2 Ų39.227%0.26822%0.217SC..G310 helixtrans-78.111.517100000115.7G306 D308 W309G306-G311 VanDerWaalsContact CA-O 3.28Å; G306-G311 WeakPolarHBondContact CA-O 3.45Å; G306-G311 PolarHBondContact N-O 3.03Å; D308-G311 PolarHBondContact O-N 2.76Å; D308-G311 PolarHBondContact OD1-N 3.35Å; W309-G311 VanDerWaalsContact C-N 3.28Å; W309-G311 PolarHBondContact O-N 3.07Å
312T97.4Very high93.9Very high9 Ų942.8 Ų42.86%0.05523%0.228CC..  trans-75.1126.1179.2-570000111.5T303 L304 W309 R310 F314 Q334 I335T303-T312 HydrophobicContact CG2-CG2 3.6Å; L304-T312 WeakPolarHBondContact O-CA 3.35Å; W309-T312 WeakPolarHBondContact O-CB 3.35Å; W309-T312 PolarHBondContact O-N 2.69Å; W309-T312 VanDerWaalsContact O-N 3.09Å; W309-T312 PolarHBondContact O-OG1 3.32Å; R310-T312 PolarHBondContact O-N 3.41Å; T312-F314 HydrophobicContact CG2-CE1 4.31Å; T312-Q334 PolarHBondContact O-OE1 3.17Å; T312-I335 WeakPolarHBondContact O-CG2 3.3Å; T312-I335 PolarHBondContact O-N 2.89Å
313T97.4Very high93Very high4 Ų443.9 Ų43.93%0.02525%0.25CC..EExtended strand (participates in β ladder)trans-115.5127.1177.3-46.10000110.4L304 Y315 Q332 Y333 Q334L304-T313 PolarHBondContact N-O 3.38Å; L304-T313 PolarHBondContact O-N 2.86Å; T313-Y315 HydrophobicContact CG2-CD2 4.14Å; T313-Y315 HydrophobicContact CG2-CE2 3.59Å; T313-Q332 HydrophobicContact CG2-CB 4.03Å; T313-Y333 WeakPolarHBondContact CA-O 3.37Å; T313-Q334 VanDerWaalsContact OG1-CD 3.29Å; T313-Q334 PolarHBondContact OG1-NE2 3.01Å; T313-Q334 VanDerWaalsContact OG1-NE2 3.07Å; T313-Q334 PolarHBondContact OG1-OE1 2.97Å
314F98.4Very high92.2Very high3 Ų350.2 Ų50.21%0.01328%0.283CS..EExtended strand (participates in β ladder)trans-91127.6168.6-52.8-66.6000109.6A220 V222 Y237 F239 T303 T312 Q332 Y333 I335 V338A220-F314 HydrophobicContact CB-CE1 4.25Å; V222-F314 HydrophobicContact CG2-CE1 4.44Å; V222-F314 HydrophobicContact CG2-CZ 3.95Å; Y237-F314 HydrophobicContact CD1-CZ 4.48Å; Y237-F314 HydrophobicContact CG-CZ 4.32Å; F239-F314 HydrophobicContact CE1-CB 4.5Å; F239-F314 HydrophobicContact CE1-CD1 4.43Å; F239-F314 HydrophobicContact CE1-CD2 4.4Å; F239-F314 HydrophobicContact CE1-CG 4.2Å; F239-F314 HydrophobicContact CE2-CD1 4.06Å; F239-F314 HydrophobicContact CE2-CE1 4.05Å; F239-F314 HydrophobicContact CZ-CB 4.37Å; F239-F314 AromaticContact CZ-CD1 3.53Å; F239-F314 HydrophobicContact CZ-CD1 3.53Å; F239-F314 AromaticContact CZ-CD2 4Å; F239-F314 HydrophobicContact CZ-CD2 4Å; F239-F314 AromaticContact CZ-CE1 3.66Å; F239-F314 HydrophobicContact CZ-CE1 3.66Å; F239-F314 HydrophobicContact CZ-CE2 4.1Å; F239-F314 AromaticContact CZ-CG 3.7Å; F239-F314 HydrophobicContact CZ-CG 3.7Å; F239-F314 AromaticContact CZ-CZ 3.93Å; F239-F314 HydrophobicContact CZ-CZ 3.93Å; T303-F314 HydrophobicContact CG2-CD1 3.86Å; T303-F314 HydrophobicContact CG2-CE1 3.71Å; T303-F314 WeakPolarHBondContact OG1-CD1 3.46Å; T312-F314 HydrophobicContact CG2-CE1 4.31Å; F314-Q332 CarbonylContact O-C 3.59Å; F314-Q332 WeakPolarHBondContact O-CA 3.29Å; F314-Y333 PolarHBondContact N-O 2.86Å; F314-Y333 PolarHBondContact O-N 2.76Å; F314-I335 HydrophobicContact CE2-CB 4.4Å; F314-I335 HydrophobicContact CE2-CD1 3.79Å; F314-I335 HydrophobicContact CZ-CD1 3.99Å; F314-V338 HydrophobicContact CD2-CG2 4.32Å; F314-V338 HydrophobicContact CE2-CG2 4.43Å
315Y98.3Very high91.6Very high0 Ų053 Ų530%030%0.3CS..EExtended strand (participates in β ladder)trans-106.2133.3169.3-71-93.1000109.6V301 F302 L304 T313 C331 Q332 L410 L421 V423 N435 L437V301-Y315 CarbonylContact C-O 3.59Å; V301-Y315 VanDerWaalsContact CA-O 3.26Å; V301-Y315 WeakPolarHBondContact CA-O 3.44Å; F302-Y315 PolarHBondContact N-O 2.92Å; F302-Y315 PolarHBondContact O-N 3.35Å; L304-Y315 HydrophobicContact CB-CD2 4.35Å; L304-Y315 HydrophobicContact CB-CE2 4.18Å; L304-Y315 HydrophobicContact CD2-CE2 3.96Å; T313-Y315 HydrophobicContact CG2-CD2 4.14Å; T313-Y315 HydrophobicContact CG2-CE2 3.59Å; Y315-C331 WeakPolarHBondContact CA-O 3.26Å; Y315-Q332 HydrophobicContact CD1-CB 3.72Å; Y315-Q332 HydrophobicContact CE1-CB 3.47Å; Y315-Q332 VanDerWaalsContact CE1-CB 3.47Å; Y315-Q332 HydrophobicContact CE1-CG 4.41Å; Y315-Q332 VanDerWaalsContact CE1-OE1 3.31Å; Y315-Q332 HydrophobicContact CG-CB 4.4Å; Y315-Q332 VanDerWaalsContact CZ-OE1 3.3Å; Y315-Q332 PolarHBondContact OH-OE1 2.82Å; Y315-L410 HydrophobicContact CD1-CD1 4.31Å; Y315-L410 HydrophobicContact CE1-CD1 3.74Å; Y315-L421 VanDerWaalsContact CB-CD2 3.43Å; Y315-L421 HydrophobicContact CG-CD2 4.44Å; Y315-V423 HydrophobicContact CD2-CG2 4Å; Y315-V423 HydrophobicContact CE2-CG1 4.34Å; Y315-V423 HydrophobicContact CG-CG2 4.14Å; Y315-N435 PolarHBondContact OH-ND2 3.07Å; Y315-L437 HydrophobicContact CE1-CD1 4.45Å
316G98.2Very high91.3Very high2 Ų251.9 Ų51.92%0.02129%0.289CS..EExtended strand (participates in β ladder)trans-124.8135.6178.800000112.5A300 F318 V330 C331A300-G316 WeakPolarHBondContact O-CA 3.44Å; G316-F318 VanDerWaalsContact O-CD2 3.27Å; G316-F318 WeakPolarHBondContact O-CD2 3.41Å; G316-F318 WeakPolarHBondContact O-CE2 3.44Å; G316-V330 WeakPolarHBondContact O-CA 3.41Å; G316-C331 PolarHBondContact N-O 2.79Å; G316-C331 PolarHBondContact O-N 3.16Å
317I98.4Very high91.4Very high0 Ų051.3 Ų51.30%028%0.282CS..EExtended strand (participates in β ladder)trans-87.3129.6164.1-69.1169.2000108.3R299 A300 V330 F418 K420 L421 I439R299-I317 HydrophobicContact CB-CG2 4.13Å; R299-I317 PolarHBondContact N-O 3.47Å; A300-I317 HydrophobicContact CB-CB 4.28Å; A300-I317 HydrophobicContact CB-CD1 4.06Å; A300-I317 HydrophobicContact CB-CG1 4.48Å; A300-I317 PolarHBondContact O-N 3.38Å; I317-V330 HydrophobicContact CG1-CG2 4.25Å; I317-F418 HydrophobicContact CD1-CB 3.94Å; I317-F418 HydrophobicContact CG1-CB 4.36Å; I317-F418 HydrophobicContact CG2-CB 3.68Å; I317-K420 WeakPolarHBondContact CD1-O 2.97Å; I317-L421 HydrophobicContact CD1-CB 3.76Å; I317-L421 HydrophobicContact CG1-CB 4.26Å; I317-I439 HydrophobicContact CD1-CG2 4.25Å
318F97.5Very high91.6Very high0 Ų044.7 Ų44.70%024%0.239CC..EExtended strand (participates in β ladder)trans-125.8145.6177.7-58-106.4000111.2A256 L284 C286 F295 N297 L298 G316 S328 A329 C331 Y333A256-F318 HydrophobicContact CB-CD1 4.18Å; A256-F318 HydrophobicContact CB-CE1 3.68Å; L284-F318 HydrophobicContact CD2-CE1 4.43Å; L284-F318 HydrophobicContact CD2-CZ 3.97Å; L284-F318 HydrophobicContact CG-CZ 4.2Å; C286-F318 HydrophobicContact CB-CB 4.41Å; C286-F318 HydrophobicContact CB-CD1 3.85Å; C286-F318 HydrophobicContact CB-CD2 3.66Å; C286-F318 HydrophobicContact CB-CE1 3.91Å; C286-F318 HydrophobicContact CB-CE2 3.77Å; C286-F318 HydrophobicContact CB-CG 3.73Å; C286-F318 HydrophobicContact CB-CZ 3.88Å; F295-F318 HydrophobicContact CB-CB 3.48Å; F295-F318 VanDerWaalsContact CB-CB 3.48Å; F295-F318 HydrophobicContact CB-CG 4.3Å; F295-F318 WeakPolarHBondContact O-CD1 3.28Å; N297-F318 CarbonylContact O-C 3.51Å; N297-F318 VanDerWaalsContact O-CA 3.23Å; N297-F318 WeakPolarHBondContact O-CA 3.19Å; L298-F318 HydrophobicContact CB-CD1 4.27Å; L298-F318 HydrophobicContact CB-CE1 4.26Å; L298-F318 HydrophobicContact CD1-CD1 3.96Å; L298-F318 HydrophobicContact CD1-CD2 4.21Å; L298-F318 HydrophobicContact CD1-CE1 3.57Å; L298-F318 HydrophobicContact CD1-CE2 3.81Å; L298-F318 HydrophobicContact CD1-CG 4.27Å; L298-F318 HydrophobicContact CD1-CZ 3.48Å; L298-F318 VanDerWaalsContact CD1-CZ 3.48Å; L298-F318 HydrophobicContact CG-CE1 4.48Å; G316-F318 VanDerWaalsContact O-CD2 3.27Å; G316-F318 WeakPolarHBondContact O-CD2 3.41Å; G316-F318 WeakPolarHBondContact O-CE2 3.44Å; F318-S328 WeakPolarHBondContact O-CA 3.31Å; F318-A329 PolarHBondContact N-O 2.82Å; F318-A329 PolarHBondContact O-N 2.63Å; F318-C331 HydrophobicContact CD2-CB 4.27Å; F318-C331 HydrophobicContact CE2-CB 3.81Å; F318-Y333 AromaticContact CE2-CE2 3.93Å; F318-Y333 HydrophobicContact CE2-CE2 3.93Å; F318-Y333 AromaticContact CZ-CE2 3.77Å; F318-Y333 HydrophobicContact CZ-CE2 3.77Å; F318-Y333 AromaticContact CZ-CZ 3.88Å; F318-Y333 VanDerWaalsContact CZ-OH 3.23Å; F318-Y333 WeakPolarHBondContact CZ-OH 3.28Å
319H93.8Very high91.8Very high29 Ų2941.6 Ų41.613%0.13422%0.223CC..EExtended strand (participates in β ladder)trans-111.7143.1172.1-66.3170.9000111.5N297 R299 V327 S328 F418N297-H319 HydrophobicContact CB-CB 4.36Å; N297-H319 PolarHBondContact N-O 2.79Å; N297-H319 PolarHBondContact ND2-O 2.86Å; N297-H319 VanDerWaalsContact ND2-O 3.16Å; N297-H319 PolarHBondContact O-N 3.38Å; R299-H319 HydrophobicContact CG-CB 4.45Å; R299-H319 PolarHBondContact NE-ND1 3.45Å; H319-V327 WeakPolarHBondContact CA-O 3.34Å; H319-S328 PolarHBondContact CD2-OG 2.93Å; H319-F418 PolarHBondContact CE1-O 2.93Å; H319-F418 PolarHBondContact NE2-O 3.4Å
320A89.1Confident91.9Very high15 Ų1539.8 Ų39.812%0.12422%0.216CC..EExtended strand (participates in β ladder)trans-140.3167.4164.600000110.1F295 V327F295-A320 HydrophobicContact CB-CB 4.48Å; F295-A320 HydrophobicContact CD1-CB 3.46Å; F295-A320 VanDerWaalsContact CD1-CB 3.46Å; F295-A320 HydrophobicContact CE1-CB 3.96Å; F295-A320 HydrophobicContact CG-CB 4.27Å; A320-V327 PolarHBondContact N-O 2.88Å; A320-V327 PolarHBondContact O-N 2.73Å
321Q82.8Confident92Very high149 Ų14933.6 Ų33.670%0.69619%0.192SC*.EExtended strand (participates in β ladder)trans-110.6137.9169-60.9-167.7-54.300109.3D326Q321-D326 WeakPolarHBondContact CG-OD1 3.25Å; Q321-D326 PolarHBondContact NE2-OD1 2.83Å
322W76.4Confident92Very high105 Ų10535 Ų3540%0.39819%0.192SC..EExtended strand (participates in β ladder)trans-12092.7177.4-172.7-59.1000108.2W23 V293 D324 V325 V327W23-W322 HydrophobicContact CH2-CE3 4.16Å; W23-W322 AromaticContact CH2-CH2 3.59Å; W23-W322 HydrophobicContact CH2-CH2 3.59Å; W23-W322 HydrophobicContact CH2-CZ2 4.48Å; W23-W322 AromaticContact CH2-CZ3 3.37Å; W23-W322 HydrophobicContact CH2-CZ3 3.37Å; W23-W322 HydrophobicContact CZ2-CZ3 4.47Å; W23-W322 HydrophobicContact CZ3-CE3 4.35Å; W23-W322 AromaticContact CZ3-CH2 3.99Å; W23-W322 HydrophobicContact CZ3-CH2 3.99Å; W23-W322 HydrophobicContact CZ3-CZ2 4.47Å; W23-W322 AromaticContact CZ3-CZ3 3.9Å; W23-W322 HydrophobicContact CZ3-CZ3 3.9Å; V293-W322 HydrophobicContact CB-CE3 4.43Å; V293-W322 HydrophobicContact CB-CZ3 3.81Å; V293-W322 HydrophobicContact CG1-CE3 4.21Å; V293-W322 HydrophobicContact CG1-CZ3 4.03Å; V293-W322 HydrophobicContact CG2-CE3 3.82Å; V293-W322 HydrophobicContact CG2-CH2 3.8Å; V293-W322 HydrophobicContact CG2-CZ3 3.26Å; W322-D324 PolarHBondContact O-N 3.42Å; W322-V325 PolarHBondContact N-O 3.5Å; W322-V325 PolarHBondContact O-N 3.16Å; W322-V327 HydrophobicContact CB-CG2 3.83Å
323G79.6Confident92Very high63 Ų6335 Ų3565%0.64919%0.191SC*.THydrogen-bonded Turntrans56-132.7-16100000109.2V325G323-V325 PolarHBondContact O-N 2.83Å
324D80.8Confident92Very high174 Ų17438 Ų3893%0.9321%0.205SC*.THydrogen-bonded Turntrans-81.712.9-179-48.4-55.2000114.4W322W322-D324 PolarHBondContact O-N 3.42Å
325V84.1Confident91.9Very high63 Ų6337.9 Ų37.938%0.38220%0.204SC..EExtended strand (participates in β ladder)trans-114.7118.4-175.5-178.10000111.4W322 G323 V327 K414W322-V325 PolarHBondContact N-O 3.5Å; W322-V325 PolarHBondContact O-N 3.16Å; G323-V325 PolarHBondContact O-N 2.83Å; V325-V327 HydrophobicContact CG1-CG2 4.46Å; V325-K414 HydrophobicContact CG1-CB 4.09Å
326D88.6Confident91.8Very high58 Ų5839.3 Ų39.331%0.3122%0.219SC..EExtended strand (participates in β ladder)trans-63.4137.9167.3-76.9-8.8000111Q321 G415 N417Q321-D326 WeakPolarHBondContact CG-OD1 3.25Å; Q321-D326 PolarHBondContact NE2-OD1 2.83Å; D326-G415 PolarHBondContact O-N 2.91Å; D326-N417 WeakPolarHBondContact CB-OD1 3.08Å; D326-N417 PolarHBondContact OD2-ND2 2.85Å
327V92Very high91.8Very high5 Ų543 Ų433%0.0324%0.238CC..EExtended strand (participates in β ladder)trans-133.9124.8-179.7-169.40000110.4F295 H319 A320 W322 V325 L412 T413 K414F295-V327 HydrophobicContact CE1-CB 4.28Å; F295-V327 HydrophobicContact CE1-CG1 3.94Å; H319-V327 WeakPolarHBondContact CA-O 3.34Å; A320-V327 PolarHBondContact N-O 2.88Å; A320-V327 PolarHBondContact O-N 2.73Å; W322-V327 HydrophobicContact CB-CG2 3.83Å; V325-V327 HydrophobicContact CG1-CG2 4.46Å; V327-L412 HydrophobicContact CG1-CD1 3.51Å; V327-L412 HydrophobicContact CG1-CG 4.07Å; V327-T413 WeakPolarHBondContact CA-O 3.43Å; V327-T413 WeakPolarHBondContact CG1-O 3.49Å; V327-K414 HydrophobicContact CG1-CG 4.44Å; V327-K414 HydrophobicContact CG2-CG 4.27Å
328S95.1Very high91.7Very high0 Ų043 Ų430%024%0.239CC..EExtended strand (participates in β ladder)trans-96.5136.2171.5-63.70000111.1F318 H319 L412 T413 V416 N417 F418F318-S328 WeakPolarHBondContact O-CA 3.31Å; H319-S328 PolarHBondContact CD2-OG 2.93Å; S328-L412 WeakPolarHBondContact O-CA 3.39Å; S328-T413 PolarHBondContact N-O 3.49Å; S328-T413 PolarHBondContact O-N 3.3Å; S328-V416 WeakPolarHBondContact CB-O 3.33Å; S328-V416 PolarHBondContact OG-O 2.98Å; S328-N417 WeakPolarHBondContact OG-CA 3.46Å; S328-F418 PolarHBondContact OG-N 3.42Å
329A95.4Very high91.7Very high0 Ų044.9 Ų44.90%025%0.247CC..EExtended strand (participates in β ladder)trans-124.7149.917300000111F295 F318 P409 L411 L412F295-A329 HydrophobicContact CB-CB 4.32Å; F295-A329 HydrophobicContact CD1-CB 3.71Å; F295-A329 HydrophobicContact CD2-CB 3.83Å; F295-A329 HydrophobicContact CE1-CB 3.98Å; F295-A329 HydrophobicContact CE2-CB 4.1Å; F295-A329 HydrophobicContact CG-CB 3.66Å; F295-A329 HydrophobicContact CZ-CB 4.19Å; F318-A329 PolarHBondContact N-O 2.82Å; F318-A329 PolarHBondContact O-N 2.63Å; A329-P409 HydrophobicContact CB-CB 4.27Å; A329-P409 HydrophobicContact CB-CG 4.26Å; A329-L411 WeakPolarHBondContact CA-O 3.24Å; A329-L412 HydrophobicContact CB-CD1 3.9Å
330V96.9Very high91.9Very high0 Ų049.4 Ų49.40%027%0.266CS..EExtended strand (participates in β ladder)trans-118.3118.9168.5-171.50000109.6G316 I317 P409 L410 L411 F418 L421 L437 I439G316-V330 WeakPolarHBondContact O-CA 3.41Å; I317-V330 HydrophobicContact CG1-CG2 4.25Å; V330-P409 CarbonylContact O-C 3.58Å; V330-P409 WeakPolarHBondContact O-CA 3.28Å; V330-L410 PolarHBondContact O-N 2.88Å; V330-L411 HydrophobicContact CB-CB 4.25Å; V330-L411 HydrophobicContact CG2-CB 4.26Å; V330-L411 HydrophobicContact CG2-CD2 4.28Å; V330-L411 PolarHBondContact N-O 2.88Å; V330-F418 HydrophobicContact CG2-CD2 4.1Å; V330-F418 HydrophobicContact CG2-CE2 4.13Å; V330-L421 HydrophobicContact CG1-CD2 4.46Å; V330-L437 HydrophobicContact CG1-CD2 3.9Å; V330-I439 HydrophobicContact CG2-CD1 4.08Å
331C96.6Very high92.3Very high0 Ų049.3 Ų49.30%026%0.264CS..EExtended strand (participates in β ladder)trans-110.5153174.8-81.70000111.1C286 Y315 G316 F318 Y333 G407C286-C331 WeakPolarHBondContact CA-SG 3.48Å; C286-C331 HydrophobicContact CB-CB 3.79Å; C286-C331 WeakPolarHBondContact CB-SG 3.28Å; C286-C331 WeakPolarHBondContact SG-CB 3.36Å; C286-C331 CovalentContact SG-SG 2.04Å; C286-C331 PolarHBondContact SG-SG 3.31Å; Y315-C331 WeakPolarHBondContact CA-O 3.26Å; G316-C331 PolarHBondContact N-O 2.79Å; G316-C331 PolarHBondContact O-N 3.16Å; F318-C331 HydrophobicContact CD2-CB 4.27Å; F318-C331 HydrophobicContact CE2-CB 3.81Å; C331-Y333 HydrophobicContact CB-CE2 3.73Å; C331-G407 PolarHBondContact SG-O 2.89Å; C331-G407 VanDerWaalsContact SG-O 3.4Å
332Q95.8Very high93Very high56 Ų5642.2 Ų42.226%0.26223%0.231SC..EExtended strand (participates in β ladder)trans-118149.4171.574.9178.39.600111.4T313 F314 Y315 L410T313-Q332 HydrophobicContact CG2-CB 4.03Å; F314-Q332 CarbonylContact O-C 3.59Å; F314-Q332 WeakPolarHBondContact O-CA 3.29Å; Y315-Q332 HydrophobicContact CD1-CB 3.72Å; Y315-Q332 HydrophobicContact CE1-CB 3.47Å; Y315-Q332 VanDerWaalsContact CE1-CB 3.47Å; Y315-Q332 HydrophobicContact CE1-CG 4.41Å; Y315-Q332 VanDerWaalsContact CE1-OE1 3.31Å; Y315-Q332 HydrophobicContact CG-CB 4.4Å; Y315-Q332 VanDerWaalsContact CZ-OE1 3.3Å; Y315-Q332 PolarHBondContact OH-OE1 2.82Å; Q332-L410 HydrophobicContact CB-CD1 4.01Å; Q332-L410 HydrophobicContact CG-CD1 3.97Å; Q332-L410 HydrophobicContact CG-CD2 4.41Å; Q332-L410 HydrophobicContact CG-CG 4.4Å
333Y97.4Very high93.9Very high9 Ų941.7 Ų41.74%0.03523%0.233CC..EExtended strand (participates in β ladder)trans-138.9127.6-179.1-54-92.3000109.4L284 E285 C286 T313 F314 F318 C331 A405 G407L284-Y333 HydrophobicContact CD1-CD1 3.51Å; L284-Y333 HydrophobicContact CD1-CD2 3.82Å; L284-Y333 HydrophobicContact CD1-CE1 3.48Å; L284-Y333 VanDerWaalsContact CD1-CE1 3.48Å; L284-Y333 HydrophobicContact CD1-CE2 3.84Å; L284-Y333 HydrophobicContact CD1-CG 3.68Å; L284-Y333 HydrophobicContact CD2-CE2 4.18Å; L284-Y333 HydrophobicContact CG-CD1 4.44Å; L284-Y333 HydrophobicContact CG-CD2 4.37Å; L284-Y333 HydrophobicContact CG-CE1 3.96Å; L284-Y333 HydrophobicContact CG-CE2 3.93Å; E285-Y333 PolarHBondContact O-OH 3.44Å; C286-Y333 WeakPolarHBondContact CA-OH 3.35Å; C286-Y333 WeakPolarHBondContact CB-OH 3.3Å; C286-Y333 PolarHBondContact N-OH 2.9Å; T313-Y333 WeakPolarHBondContact CA-O 3.37Å; F314-Y333 PolarHBondContact N-O 2.86Å; F314-Y333 PolarHBondContact O-N 2.76Å; F318-Y333 AromaticContact CE2-CE2 3.93Å; F318-Y333 HydrophobicContact CE2-CE2 3.93Å; F318-Y333 AromaticContact CZ-CE2 3.77Å; F318-Y333 HydrophobicContact CZ-CE2 3.77Å; F318-Y333 AromaticContact CZ-CZ 3.88Å; F318-Y333 VanDerWaalsContact CZ-OH 3.23Å; F318-Y333 WeakPolarHBondContact CZ-OH 3.28Å; C331-Y333 HydrophobicContact CB-CE2 3.73Å; Y333-A405 HydrophobicContact CD1-CB 4.3Å; Y333-G407 VanDerWaalsContact CE1-N 3.28Å
334Q96.6Very high94.7Very high67 Ų6739.8 Ų39.831%0.31321%0.213SC..EExtended strand (participates in β ladder)trans-83.7140.4173.4-61.7-59.3-13.700110.5T312 T313 G336 D337 V338T312-Q334 PolarHBondContact O-OE1 3.17Å; T313-Q334 VanDerWaalsContact OG1-CD 3.29Å; T313-Q334 PolarHBondContact OG1-NE2 3.01Å; T313-Q334 VanDerWaalsContact OG1-NE2 3.07Å; T313-Q334 PolarHBondContact OG1-OE1 2.97Å; Q334-G336 PolarHBondContact O-N 2.84Å; Q334-G336 VanDerWaalsContact O-N 3.17Å; Q334-D337 PolarHBondContact O-N 3.04Å; Q334-V338 PolarHBondContact O-N 2.89Å
335I97.2Very high95.5Very high0 Ų033.2 Ų33.20%018%0.18CC..Hα-helixtrans-54.2-36178-177.260.5000112.4V222 Y237 W309 R310 T312 F314 D337 V338 K339V222-I335 HydrophobicContact CG1-CD1 4.25Å; V222-I335 HydrophobicContact CG1-CG1 4.15Å; V222-I335 HydrophobicContact CG2-CD1 4.21Å; Y237-I335 HydrophobicContact CE1-CD1 4.31Å; Y237-I335 HydrophobicContact CE2-CD1 4.01Å; W309-I335 HydrophobicContact CE3-CG1 4.33Å; W309-I335 HydrophobicContact CE3-CG2 4.39Å; W309-I335 HydrophobicContact CZ3-CG1 4.29Å; W309-I335 WeakPolarHBondContact O-CG2 3.38Å; R310-I335 WeakPolarHBondContact O-CG2 3.5Å; T312-I335 WeakPolarHBondContact O-CG2 3.3Å; T312-I335 PolarHBondContact O-N 2.89Å; F314-I335 HydrophobicContact CE2-CB 4.4Å; F314-I335 HydrophobicContact CE2-CD1 3.79Å; F314-I335 HydrophobicContact CZ-CD1 3.99Å; I335-D337 VanDerWaalsContact C-N 3.3Å; I335-D337 PolarHBondContact O-N 3.04Å; I335-V338 PolarHBondContact O-N 2.95Å; I335-K339 WeakPolarHBondContact O-CB 3.49Å; I335-K339 PolarHBondContact O-N 2.8Å
336G96.3Very high96.1Very high31 Ų3130.4 Ų30.432%0.3216%0.163SC..Hα-helixtrans-61.3-34.8178.200000113.7Q334 K340Q334-G336 PolarHBondContact O-N 2.84Å; Q334-G336 VanDerWaalsContact O-N 3.17Å; G336-K340 WeakPolarHBondContact O-CE 3.47Å; G336-K340 VanDerWaalsContact O-CG 3.26Å; G336-K340 WeakPolarHBondContact O-CG 3.24Å; G336-K340 PolarHBondContact O-N 2.72Å
337D96.6Very high96.5Very high79 Ų7929 Ų2942%0.42215%0.154SC..Hα-helixtrans-81-33.9177.7-61.4-48.5000111.8Q334 I335 K340 V341Q334-D337 PolarHBondContact O-N 3.04Å; I335-D337 VanDerWaalsContact C-N 3.3Å; I335-D337 PolarHBondContact O-N 3.04Å; D337-K340 IonicContact OD1-NZ 2.72Å; D337-K340 PolarHBondContact OD1-NZ 3.31Å; D337-V341 PolarHBondContact O-N 3.25Å
338V98.1Very high96.5Very high1 Ų131.8 Ų31.81%0.00617%0.167CC..Hα-helixtrans-62.9-42.2170.4174.20000110.9Y237 V258 F314 Q334 I335 V341 F342 A405Y237-V338 HydrophobicContact CE1-CG1 3.78Å; V258-V338 HydrophobicContact CG1-CG1 4.2Å; V258-V338 HydrophobicContact CG2-CG1 4.21Å; F314-V338 HydrophobicContact CD2-CG2 4.32Å; F314-V338 HydrophobicContact CE2-CG2 4.43Å; Q334-V338 PolarHBondContact O-N 2.89Å; I335-V338 PolarHBondContact O-N 2.95Å; V338-V341 PolarHBondContact O-N 3.05Å; V338-F342 HydrophobicContact CG1-CD2 4.15Å; V338-F342 HydrophobicContact CG1-CE2 3.7Å; V338-F342 WeakPolarHBondContact O-CD2 3.35Å; V338-F342 PolarHBondContact O-N 2.91Å; V338-A405 HydrophobicContact CG2-CB 4.18Å
339K96.3Very high96.3Very high39 Ų3936 Ų3617%0.1718%0.183CC..Hα-helixtrans-63.5-45.7179.7-166174.8-169.4-78.10112E224 W309 I335 V341 F342 E343E224-K339 WeakPolarHBondContact OE2-CE 3.5Å; W309-K339 HydrophobicContact CH2-CD 4.02Å; W309-K339 HydrophobicContact CZ3-CD 4.24Å; I335-K339 WeakPolarHBondContact O-CB 3.49Å; I335-K339 PolarHBondContact O-N 2.8Å; K339-V341 PolarHBondContact O-N 2.96Å; K339-F342 PolarHBondContact O-N 3.32Å; K339-E343 WeakPolarHBondContact CG-OE1 3.21Å; K339-E343 IonicContact NZ-OE1 3.18Å; K339-E343 PolarHBondContact NZ-OE1 3.02Å; K339-E343 WeakPolarHBondContact O-CG 3.44Å; K339-E343 PolarHBondContact O-N 3Å; K339-E343 VanDerWaalsContact O-N 3.07Å
340K97.4Very high95.9Very high124 Ų12440.1 Ų40.154%0.53920%0.199SC..Hα-helixtrans-53-38.7174.9-70.6165.4-157.6167.90112.9G336 D337 E343 G344G336-K340 WeakPolarHBondContact O-CE 3.47Å; G336-K340 VanDerWaalsContact O-CG 3.26Å; G336-K340 WeakPolarHBondContact O-CG 3.24Å; G336-K340 PolarHBondContact O-N 2.72Å; D337-K340 IonicContact OD1-NZ 2.72Å; D337-K340 PolarHBondContact OD1-NZ 3.31Å; K340-E343 CarbonylContact O-C 3.52Å; K340-E343 PolarHBondContact O-N 2.74Å; K340-G344 PolarHBondContact O-N 2.93Å
341V98.3Very high95.4Very high13 Ų1346.9 Ų46.98%0.07923%0.23CC..Hα-helixtrans-66.9-39.3179.81730000111.7A282 D337 V338 K339 E343 G344 M401 D403A282-V341 HydrophobicContact CB-CG1 3.55Å; D337-V341 PolarHBondContact O-N 3.25Å; V338-V341 PolarHBondContact O-N 3.05Å; K339-V341 PolarHBondContact O-N 2.96Å; V341-E343 VanDerWaalsContact C-N 3.29Å; V341-E343 PolarHBondContact O-N 2.76Å; V341-G344 PolarHBondContact O-N 2.94Å; V341-M401 HydrophobicContact CG1-CB 4.07Å; V341-M401 HydrophobicContact CG1-CG 4.41Å; V341-M401 WeakPolarHBondContact O-CE 3.3Å; V341-D403 HydrophobicContact CG1-CB 4.25Å; V341-D403 WeakPolarHBondContact CG1-O 3.39Å
342F98Very high95Very high0 Ų052.2 Ų52.20%028%0.275CS..Hα-helixtrans-73.6-20174.7-68.2-67.8000113.7Y237 V258 R260 Q280 A282 V338 K339 R367 M401Y237-F342 AromaticContact CE1-CE2 3.96Å; Y237-F342 HydrophobicContact CE1-CE2 3.96Å; V258-F342 HydrophobicContact CG1-CE2 4.39Å; V258-F342 HydrophobicContact CG1-CZ 4.29Å; R260-F342 HydrophobicContact CG-CD1 4.31Å; R260-F342 HydrophobicContact CG-CD2 4.43Å; R260-F342 HydrophobicContact CG-CE1 4.15Å; R260-F342 HydrophobicContact CG-CE2 4.27Å; R260-F342 HydrophobicContact CG-CG 4.45Å; R260-F342 HydrophobicContact CG-CZ 4.12Å; R260-F342 VanDerWaalsContact CZ-CB 3.41Å; Q280-F342 HydrophobicContact CB-CD1 3.59Å; Q280-F342 HydrophobicContact CB-CE1 3.7Å; A282-F342 HydrophobicContact CB-CE1 4.09Å; A282-F342 HydrophobicContact CB-CZ 4.09Å; V338-F342 HydrophobicContact CG1-CD2 4.15Å; V338-F342 HydrophobicContact CG1-CE2 3.7Å; V338-F342 WeakPolarHBondContact O-CD2 3.35Å; V338-F342 PolarHBondContact O-N 2.91Å; K339-F342 PolarHBondContact O-N 3.32Å; F342-R367 PolarHBondContact O-NH2 2.97Å; F342-M401 HydrophobicContact CD1-CG 3.77Å; F342-M401 HydrophobicContact CD1-SD 4.25Å; F342-M401 HydrophobicContact CE1-CG 4.19Å
343E95.7Very high94.5Very high94 Ų9452.7 Ų52.744%0.43928%0.284SS..Hα-helixtrans-83.7-15.4169.8-68162.7169.800112.4K339 K340 V341 R367K339-E343 WeakPolarHBondContact CG-OE1 3.21Å; K339-E343 IonicContact NZ-OE1 3.18Å; K339-E343 PolarHBondContact NZ-OE1 3.02Å; K339-E343 WeakPolarHBondContact O-CG 3.44Å; K339-E343 PolarHBondContact O-N 3Å; K339-E343 VanDerWaalsContact O-N 3.07Å; K340-E343 CarbonylContact O-C 3.52Å; K340-E343 PolarHBondContact O-N 2.74Å; V341-E343 VanDerWaalsContact C-N 3.29Å; V341-E343 PolarHBondContact O-N 2.76Å; E343-R367 VanDerWaalsContact O-CZ 3.23Å; E343-R367 PolarHBondContact O-NH1 3.3Å; E343-R367 PolarHBondContact O-NH2 2.9Å; E343-R367 VanDerWaalsContact O-NH2 3.09Å
344G96.1Very high93.9Very high22 Ų2256.8 Ų56.823%0.22730%0.303CS..SBendtrans-74.6-154.4-179.700000115.6K340 V341 R367K340-G344 PolarHBondContact O-N 2.93Å; V341-G344 PolarHBondContact O-N 2.94Å; G344-R367 PolarHBondContact O-NH2 2.82Å
345S96.7Very high93.6Very high36 Ų3661.2 Ų61.225%0.25232%0.317SS..  trans-85.8146.7-176.9-58.50000112.5E402 D403S345-E402 WeakPolarHBondContact O-CB 3.35Å; S345-E402 PolarHBondContact O-N 2.88Å; S345-D403 PolarHBondContact N-OD2 3.48Å
346Y98Very high93.3Very high4 Ų463.2 Ų63.22%0.01633%0.325CS..BIsolated β-bridgetrans-79.4162171-53.9-88.5000111.7Y359 T363 R367 P368 F394 H398 M401Y346-Y359 WeakPolarHBondContact O-CB 3.23Å; Y346-Y359 PolarHBondContact O-N 3.27Å; Y346-T363 HydrophobicContact CE2-CG2 3.8Å; Y346-R367 VanDerWaalsContact OH-CG 3.3Å; Y346-R367 WeakPolarHBondContact OH-CG 3.48Å; Y346-R367 PolarHBondContact OH-NE 2.82Å; Y346-R367 VanDerWaalsContact OH-NE 3.12Å; Y346-R367 PolarHBondContact OH-NH2 3.3Å; Y346-P368 PolarHBondContact OH-O 3.18Å; Y346-F394 HydrophobicContact CD1-CE1 4.09Å; Y346-F394 AromaticContact CD2-CE1 3.68Å; Y346-F394 HydrophobicContact CD2-CE1 3.68Å; Y346-F394 AromaticContact CD2-CZ 3.93Å; Y346-F394 HydrophobicContact CD2-CZ 3.93Å; Y346-F394 HydrophobicContact CE1-CE1 4.32Å; Y346-F394 AromaticContact CE2-CE1 3.95Å; Y346-F394 HydrophobicContact CE2-CE1 3.95Å; Y346-F394 HydrophobicContact CE2-CZ 4.42Å; Y346-F394 AromaticContact CG-CE1 3.78Å; Y346-F394 HydrophobicContact CG-CE1 3.78Å; Y346-F394 HydrophobicContact CG-CZ 4.25Å; Y346-H398 HydrophobicContact CD1-CB 4.21Å; Y346-H398 HydrophobicContact CG-CB 4.36Å; Y346-M401 HydrophobicContact CD1-CE 3.95Å; Y346-M401 HydrophobicContact CD1-SD 3.93Å; Y346-M401 HydrophobicContact CE1-CE 4.03Å; Y346-M401 HydrophobicContact CE1-SD 4.09Å; Y346-M401 HydrophobicContact CG-CE 4.38Å
347K95.5Very high93.1Very high30 Ų3062.4 Ų62.413%0.1332%0.317CS..EExtended strand (participates in β ladder)trans-110.1137.7172.3-155.4176.4-155.8100.50110.2E246 W356 L400 E402E246-K347 HydrophobicContact CB-CD 3.78Å; E246-K347 HydrophobicContact CG-CD 3.88Å; K347-W356 HydrophobicContact CD-CB 4.31Å; K347-W356 HydrophobicContact CD-CE3 4.46Å; K347-W356 HydrophobicContact CG-CB 4.41Å; K347-W356 HydrophobicContact CG-CE3 4.13Å; K347-L400 HydrophobicContact CB-CB 4.42Å; K347-L400 HydrophobicContact CB-CD2 4.28Å; K347-L400 HydrophobicContact CB-CG 4.06Å; K347-L400 HydrophobicContact CD-CD2 3.76Å; K347-L400 HydrophobicContact CD-CG 4.22Å; K347-L400 PolarHBondContact N-O 2.81Å; K347-E402 HydrophobicContact CB-CB 4.38Å; K347-E402 WeakPolarHBondContact CD-OE2 3.4Å; K347-E402 VanDerWaalsContact CE-OE2 3.25Å; K347-E402 WeakPolarHBondContact CE-OE2 3.5Å; K347-E402 VanDerWaalsContact CG-OE2 3.27Å; K347-E402 WeakPolarHBondContact CG-OE2 3.33Å; K347-E402 IonicContact NZ-OE2 3.85Å; K347-E402 PolarHBondContact NZ-OE2 2.93Å
348E93.2Very high93Very high62 Ų6263.9 Ų63.929%0.2932%0.316SS..EExtended strand (participates in β ladder)trans-127.8147.1-178.5-178.1178.7-139.100110.2W356 G357 Y359 H398E348-W356 VanDerWaalsContact C-CE3 3.44Å; E348-W356 WeakPolarHBondContact O-CA 3.46Å; E348-G357 PolarHBondContact N-O 3.04Å; E348-G357 PolarHBondContact O-N 3.42Å; E348-Y359 HydrophobicContact CB-CD2 4.26Å; E348-Y359 WeakPolarHBondContact OE2-CD2 3.48Å; E348-H398 WeakPolarHBondContact CG-NE2 3.28Å; E348-H398 IonicContact OE1-NE2 3.95Å; E348-H398 PolarHBondContact OE1-NE2 2.75Å
349Y90Very high92.9Very high88 Ų8866.1 Ų66.135%0.34533%0.325SS..EExtended strand (participates in β ladder)trans-82.8109.8166.9-177-101.4000109.7E351 Q354 W356Y349-E351 HydrophobicContact CD1-CG 4.18Å; Y349-E351 HydrophobicContact CE1-CG 4.24Å; Y349-E351 PolarHBondContact O-N 2.59Å; Y349-Q354 VanDerWaalsContact CE2-C 3.45Å; Y349-Q354 VanDerWaalsContact CE2-O 3.29Å; Y349-Q354 WeakPolarHBondContact CE2-O 2.93Å; Y349-Q354 VanDerWaalsContact OH-C 3.23Å; Y349-Q354 VanDerWaalsContact OH-CA 3.27Å; Y349-Q354 WeakPolarHBondContact OH-CA 3.36Å; Y349-Q354 PolarHBondContact OH-O 2.96Å; Y349-Q354 PolarHBondContact OH-OE1 3.01Å; Y349-W356 AromaticContact CD2-CD1 3.65Å; Y349-W356 HydrophobicContact CD2-CD2 4.3Å; Y349-W356 HydrophobicContact CD2-CG 4.1Å; Y349-W356 AromaticContact CD2-NE1 3.61Å
350R88.1Confident92.7Very high87 Ų8769.3 Ų69.333%0.32835%0.348SS..EExtended strand (participates in β ladder)trans-88.196.8-177.3-66.7175.8172.6-116.7-0.3109.5A352 S353 Q354 R355 R358 T360R350-A352 VanDerWaalsContact C-N 3.27Å; R350-A352 PolarHBondContact O-N 2.92Å; R350-S353 WeakPolarHBondContact CB-OG 3.37Å; R350-S353 CarbonylContact O-C 3.5Å; R350-S353 PolarHBondContact O-N 2.87Å; R350-S353 PolarHBondContact O-OG 2.96Å; R350-Q354 PolarHBondContact O-N 3.4Å; R350-R355 PolarHBondContact N-O 3.33Å; R350-R355 PolarHBondContact O-N 2.88Å; R350-R358 PolarHBondContact NE-O 2.78Å; R350-R358 PolarHBondContact NH2-O 3.17Å; R350-T360 PolarHBondContact NH2-OG1 2.81Å
351E86.5Confident92.5Very high142 Ų14265.4 Ų65.466%0.66434%0.343SS*.G310 helixtrans-51.9-42.8-177.2-64.2-174.7161.300113.2Y349 S353 Q354Y349-E351 HydrophobicContact CD1-CG 4.18Å; Y349-E351 HydrophobicContact CE1-CG 4.24Å; Y349-E351 PolarHBondContact O-N 2.59Å; E351-S353 PolarHBondContact O-N 3.2Å; E351-S353 VanDerWaalsContact O-N 3.14Å; E351-Q354 PolarHBondContact O-N 3.24Å; E351-Q354 PolarHBondContact O-NE2 2.83Å
352A87.5Confident92.3Very high113 Ų11369 Ų6993%0.93437%0.374SS*.G310 helixtrans-61.7-21.5-179.400000114.6R350R350-A352 VanDerWaalsContact C-N 3.27Å; R350-A352 PolarHBondContact O-N 2.92Å
353S84.4Confident92.2Very high65 Ų6572.1 Ų72.146%0.45539%0.393SS..G310 helixtrans-117.78.617453.20000113.2R350 E351 R355R350-S353 WeakPolarHBondContact CB-OG 3.37Å; R350-S353 CarbonylContact O-C 3.5Å; R350-S353 PolarHBondContact O-N 2.87Å; R350-S353 PolarHBondContact O-OG 2.96Å; E351-S353 PolarHBondContact O-N 3.2Å; E351-S353 VanDerWaalsContact O-N 3.14Å; S353-R355 WeakPolarHBondContact O-CG 3.47Å; S353-R355 PolarHBondContact O-N 2.85Å; S353-R355 WeakPolarHBondContact OG-CG 3.43Å
354Q86.4Confident92.2Very high95 Ų9569.1 Ų69.144%0.44438%0.382SS..THydrogen-bonded Turntrans50.625.6179.3-66.2-73-78.600115.2Y349 R350 E351Y349-Q354 VanDerWaalsContact CE2-C 3.45Å; Y349-Q354 VanDerWaalsContact CE2-O 3.29Å; Y349-Q354 WeakPolarHBondContact CE2-O 2.93Å; Y349-Q354 VanDerWaalsContact OH-C 3.23Å; Y349-Q354 VanDerWaalsContact OH-CA 3.27Å; Y349-Q354 WeakPolarHBondContact OH-CA 3.36Å; Y349-Q354 PolarHBondContact OH-O 2.96Å; Y349-Q354 PolarHBondContact OH-OE1 3.01Å; R350-Q354 PolarHBondContact O-N 3.4Å; E351-Q354 PolarHBondContact O-N 3.24Å; E351-Q354 PolarHBondContact O-NE2 2.83Å
355R88.8Confident92.2Very high160 Ų16073 Ų7360%0.60441%0.405SS*.EExtended strand (participates in β ladder)trans-140.4158.7-171.766179.7-75.2171.71.1113.2R350 S353R350-R355 PolarHBondContact N-O 3.33Å; R350-R355 PolarHBondContact O-N 2.88Å; S353-R355 WeakPolarHBondContact O-CG 3.47Å; S353-R355 PolarHBondContact O-N 2.85Å; S353-R355 WeakPolarHBondContact OG-CG 3.43Å
356W91.4Very high92.2Very high43 Ų4371.4 Ų71.416%0.16339%0.394CS..EExtended strand (participates in β ladder)trans-77.8154169.3-66.884.7000112.6A209 L245 E246 K347 E348 Y349 L400A209-W356 HydrophobicContact CB-CH2 4.27Å; L245-W356 HydrophobicContact CB-CZ2 4.18Å; L245-W356 PolarHBondContact O-NE1 3.08Å; E246-W356 HydrophobicContact CB-CB 3.75Å; E246-W356 HydrophobicContact CB-CD2 4.13Å; E246-W356 HydrophobicContact CB-CG 3.72Å; K347-W356 HydrophobicContact CD-CB 4.31Å; K347-W356 HydrophobicContact CD-CE3 4.46Å; K347-W356 HydrophobicContact CG-CB 4.41Å; K347-W356 HydrophobicContact CG-CE3 4.13Å; E348-W356 VanDerWaalsContact C-CE3 3.44Å; E348-W356 WeakPolarHBondContact O-CA 3.46Å; Y349-W356 AromaticContact CD2-CD1 3.65Å; Y349-W356 HydrophobicContact CD2-CD2 4.3Å; Y349-W356 HydrophobicContact CD2-CG 4.1Å; Y349-W356 AromaticContact CD2-NE1 3.61Å; W356-L400 HydrophobicContact CZ3-CD2 4.48Å
357G92.1Very high92.1Very high14 Ų1474.9 Ų74.914%0.14441%0.407CS..EExtended strand (participates in β ladder)trans-178.3175.2168.800000112.7E348 Y359E348-G357 PolarHBondContact N-O 3.04Å; E348-G357 PolarHBondContact O-N 3.42Å; G357-Y359 PolarHBondContact O-N 3.35Å
358R94.9Very high92.2Very high109 Ų10973.5 Ų73.541%0.41140%0.401SS..EExtended strand (participates in β ladder)trans-46.5132.9176.5-171.5169.1-82.2-156.4-7.6112.6R350 E402 D403R350-R358 PolarHBondContact NE-O 2.78Å; R350-R358 PolarHBondContact NH2-O 3.17Å; R358-E402 HydrophobicContact CB-CB 4.43Å; R358-E402 HydrophobicContact CB-CG 3.73Å; R358-E402 WeakPolarHBondContact CB-OE1 3.29Å; R358-E402 HydrophobicContact CG-CB 4.43Å; R358-E402 HydrophobicContact CG-CG 3.98Å; R358-E402 VanDerWaalsContact N-CD 3.33Å; R358-E402 PolarHBondContact N-OE1 2.9Å; R358-E402 PolarHBondContact N-OE2 2.83Å; R358-D403 IonicContact CZ-OD1 2.7Å; R358-D403 IonicContact NH2-OD1 2.79Å; R358-D403 PolarHBondContact NH2-OD1 2.88Å; R358-D403 IonicContact NH2-OD2 2.76Å
359Y95Very high92.4Very high49 Ų4970.8 Ų70.819%0.19239%0.39CS..  trans-70.2133.1166.9-178.9-102.8000110.3Y346 E348 G357 G361 A362 F394Y346-Y359 WeakPolarHBondContact O-CB 3.23Å; Y346-Y359 PolarHBondContact O-N 3.27Å; E348-Y359 HydrophobicContact CB-CD2 4.26Å; E348-Y359 WeakPolarHBondContact OE2-CD2 3.48Å; G357-Y359 PolarHBondContact O-N 3.35Å; Y359-G361 WeakPolarHBondContact CE1-O 3.47Å; Y359-G361 VanDerWaalsContact CZ-CA 3.48Å; Y359-G361 WeakPolarHBondContact OH-CA 3.4Å; Y359-A362 PolarHBondContact OH-O 3Å; Y359-F394 HydrophobicContact CD1-CE2 4.16Å; Y359-F394 AromaticContact CD1-CZ 3.82Å; Y359-F394 HydrophobicContact CD1-CZ 3.82Å; Y359-F394 HydrophobicContact CD2-CE2 4.47Å; Y359-F394 HydrophobicContact CD2-CZ 4.43Å; Y359-F394 AromaticContact CE1-CE2 3.62Å; Y359-F394 HydrophobicContact CE1-CE2 3.62Å; Y359-F394 AromaticContact CE1-CZ 3.75Å; Y359-F394 HydrophobicContact CE1-CZ 3.75Å; Y359-F394 HydrophobicContact CE2-CE2 4Å; Y359-F394 HydrophobicContact CE2-CZ 4.4Å; Y359-F394 HydrophobicContact CG-CZ 4.17Å; Y359-F394 AromaticContact CZ-CE2 3.55Å
360T93.4Very high92.7Very high106 Ų10667.9 Ų67.965%0.6538%0.382SS*.  trans-127.613.8-174.857.20000114.1R350R350-T360 PolarHBondContact NH2-OG1 2.81Å
361G92.4Very high93.1Very high42 Ų4263.9 Ų63.943%0.43337%0.367SS..SBendtrans-92.3-173.817400000113.1Y359 T363Y359-G361 WeakPolarHBondContact CE1-O 3.47Å; Y359-G361 VanDerWaalsContact CZ-CA 3.48Å; Y359-G361 WeakPolarHBondContact OH-CA 3.4Å; G361-T363 PolarHBondContact O-N 3.2Å
362A94.5Very high93.6Very high89 Ų8958.1 Ų58.174%0.73634%0.341SS*.PPolyproline II helixtrans-72.8124.8173.700000110.8Y359Y359-A362 PolarHBondContact OH-O 3Å
363T95.6Very high94Very high64 Ų6454.2 Ų54.239%0.39331%0.306SS..PPolyproline II helixtrans-76.7132.7172.9-60.50000109.5Y346 G361 P368Y346-T363 HydrophobicContact CE2-CG2 3.8Å; G361-T363 PolarHBondContact O-N 3.2Å; T363-P368 HydrophobicContact CG2-CG 4.25Å
364P96.5Very high94.6Very high32 Ų3254.4 Ų54.421%0.20830%0.302CS..PPolyproline II helixtrans-57.4160.2174.1-27.635.4000114.5P366 P368 T391 F394P364-P366 CarbonylContact C-O 3.53Å; P364-P368 HydrophobicContact CB-CG 4.13Å; P364-P368 HydrophobicContact CG-CG 4.11Å; P364-T391 WeakPolarHBondContact CB-OG1 3.39Å; P364-F394 HydrophobicContact CG-CB 3.9Å; P364-F394 HydrophobicContact CG-CD2 3.87Å; P364-F394 HydrophobicContact CG-CG 4.02Å
365S94.8Very high95Very high103 Ų10353.1 Ų53.172%0.7230%0.303SS*.SBendtrans-123.8133.1170.6-169.40000110
366P96.1Very high95.3Very high3 Ų346.3 Ų46.32%0.01928%0.279CS..SBendcis-56.1159-7.1-29.839.5000114.4P364 P368 D376 Y381 L387 T391P364-P366 CarbonylContact C-O 3.53Å; P366-P368 WeakPolarHBondContact O-CD 3.34Å; P366-D376 VanDerWaalsContact CB-OD1 3.28Å; P366-D376 WeakPolarHBondContact CB-OD1 3.41Å; P366-D376 WeakPolarHBondContact CG-OD1 3.22Å; P366-Y381 HydrophobicContact CG-CD2 3.42Å; P366-Y381 VanDerWaalsContact CG-CD2 3.42Å; P366-Y381 HydrophobicContact CG-CE2 3.55Å; P366-Y381 HydrophobicContact CG-CG 3.99Å; P366-L387 HydrophobicContact CB-CD2 3.79Å; P366-L387 HydrophobicContact CG-CD2 3.75Å; P366-T391 WeakPolarHBondContact O-CG2 3.49Å; P366-T391 PolarHBondContact O-OG1 2.97Å
367R96.9Very high95.6Very high77 Ų7748.9 Ų48.929%0.29129%0.288SS..  trans-64.7125.7-172.8179.4176167.7111.63.1111F342 E343 G344 Y346 G369 S370F342-R367 PolarHBondContact O-NH2 2.97Å; E343-R367 VanDerWaalsContact O-CZ 3.23Å; E343-R367 PolarHBondContact O-NH1 3.3Å; E343-R367 PolarHBondContact O-NH2 2.9Å; E343-R367 VanDerWaalsContact O-NH2 3.09Å; G344-R367 PolarHBondContact O-NH2 2.82Å; Y346-R367 VanDerWaalsContact OH-CG 3.3Å; Y346-R367 WeakPolarHBondContact OH-CG 3.48Å; Y346-R367 PolarHBondContact OH-NE 2.82Å; Y346-R367 VanDerWaalsContact OH-NE 3.12Å; Y346-R367 PolarHBondContact OH-NH2 3.3Å; R367-G369 PolarHBondContact O-N 3.04Å; R367-S370 PolarHBondContact O-N 3.3Å; R367-S370 VanDerWaalsContact O-N 3.17Å; R367-S370 PolarHBondContact O-OG 3.31Å; R367-S370 VanDerWaalsContact O-OG 3.1Å
368P98.1Very high95.8Very high1 Ų155.9 Ų55.91%0.00632%0.317CS..THydrogen-bonded Turntrans-56.4113.1179-27.535.4000113.6Q280 Y346 T363 P364 P366 T391 F394 A395Q280-P368 PolarHBondContact NE2-O 2.67Å; Y346-P368 PolarHBondContact OH-O 3.18Å; T363-P368 HydrophobicContact CG2-CG 4.25Å; P364-P368 HydrophobicContact CB-CG 4.13Å; P364-P368 HydrophobicContact CG-CG 4.11Å; P366-P368 WeakPolarHBondContact O-CD 3.34Å; P368-T391 HydrophobicContact CB-CG2 4.36Å; P368-T391 HydrophobicContact CG-CG2 4.12Å; P368-F394 HydrophobicContact CB-CB 4.26Å; P368-F394 HydrophobicContact CB-CD1 3.52Å; P368-F394 HydrophobicContact CB-CE1 4.27Å; P368-F394 HydrophobicContact CB-CG 4.22Å; P368-F394 HydrophobicContact CG-CB 3.86Å; P368-F394 HydrophobicContact CG-CD1 3.42Å; P368-F394 VanDerWaalsContact CG-CD1 3.42Å; P368-F394 HydrophobicContact CG-CE1 4.14Å; P368-F394 HydrophobicContact CG-CG 3.75Å; P368-A395 HydrophobicContact CB-CB 4.1Å
369G96.2Very high95.8Very high4 Ų456 Ų564%0.04133%0.326CS..THydrogen-bonded Turntrans88.68.1176.800000116.2Q280 R367Q280-G369 PolarHBondContact NE2-O 2.8Å; Q280-G369 PolarHBondContact OE1-O 3.49Å; R367-G369 PolarHBondContact O-N 3.04Å
370S96.4Very high95.8Very high28 Ų2855.6 Ų55.620%0.19634%0.337CS..PPolyproline II helixtrans-78.1162.4164.3640000111.5T278 R367T278-S370 WeakPolarHBondContact CG2-O 3.41Å; R367-S370 PolarHBondContact O-N 3.3Å; R367-S370 VanDerWaalsContact O-N 3.17Å; R367-S370 PolarHBondContact O-OG 3.31Å; R367-S370 VanDerWaalsContact O-OG 3.1Å
371C97.2Very high95.9Very high2 Ų253.4 Ų53.41%0.01432%0.317CS..PPolyproline II helixtrans-71.6163.1163.3-47.70000109.7D232 D233 K235 C262 T373D232-C371 WeakPolarHBondContact OD1-CB 3.26Å; D233-C371 HydrophobicContact CB-CB 3.83Å; K235-C371 WeakPolarHBondContact CE-SG 3.47Å; C262-C371 HydrophobicContact CB-CB 3.87Å; C262-C371 WeakPolarHBondContact CB-SG 3.43Å; C262-C371 WeakPolarHBondContact SG-CA 3.11Å; C262-C371 WeakPolarHBondContact SG-CB 3.36Å; C262-C371 PolarHBondContact SG-N 3.14Å; C262-C371 CovalentContact SG-SG 2.03Å; C262-C371 PolarHBondContact SG-SG 2.85Å; C371-T373 PolarHBondContact O-N 3.39Å
372I97.1Very high96Very high22 Ų2256.2 Ų56.211%0.11332%0.322CS..PPolyproline II helixtrans-76.4121175.4-51.3-56.8000108.7D376 R377 Y381 L387I372-D376 HydrophobicContact CG2-CB 3.79Å; I372-R377 VanDerWaalsContact C-NH1 3.27Å; I372-R377 HydrophobicContact CG2-CG 4.22Å; I372-R377 PolarHBondContact O-NH1 2.81Å; I372-Y381 WeakPolarHBondContact CG2-O 3.46Å; I372-L387 HydrophobicContact CD1-CD1 4.13Å; I372-L387 HydrophobicContact CD1-CD2 3.86Å; I372-L387 HydrophobicContact CD1-CG 4.08Å
373T96.1Very high96.1Very high31 Ų3153.3 Ų53.319%0.1930%0.297CS..  trans-98.4177.3-178.867.30000112.7D230 C371 S375 D376 R377D230-T373 CarbonylContact O-C 3.59Å; D230-T373 WeakPolarHBondContact O-CA 3.38Å; D230-T373 WeakPolarHBondContact O-CB 3.27Å; C371-T373 PolarHBondContact O-N 3.39Å; T373-S375 VanDerWaalsContact C-N 3.33Å; T373-S375 PolarHBondContact OG1-N 3.48Å; T373-D376 WeakPolarHBondContact CB-OD2 3.5Å; T373-D376 PolarHBondContact N-OD2 3.38Å; T373-D376 PolarHBondContact O-N 2.79Å; T373-D376 VanDerWaalsContact OG1-CG 3.32Å; T373-D376 PolarHBondContact OG1-N 3.44Å; T373-D376 PolarHBondContact OG1-OD2 2.84Å; T373-R377 WeakPolarHBondContact O-CG 3.27Å; T373-R377 PolarHBondContact O-N 2.85Å; T373-R377 VanDerWaalsContact O-N 3.16Å; T373-R377 PolarHBondContact O-NH1 2.92Å
374N95.8Very high96.1Very high69 Ų6950.4 Ų50.437%0.36928%0.279SS..Hα-helixtrans-59.8-43.5172.2-72.7-19.2000111.2Q229 D230 G231 D376 R377 E378Q229-N374 PolarHBondContact O-ND2 2.87Å; Q229-N374 VanDerWaalsContact O-ND2 3.08Å; D230-N374 PolarHBondContact O-N 3.37Å; G231-N374 PolarHBondContact N-ND2 2.94Å; N374-D376 VanDerWaalsContact C-N 3.31Å; N374-D376 PolarHBondContact O-N 3.45Å; N374-R377 WeakPolarHBondContact O-CB 3.47Å; N374-R377 PolarHBondContact O-N 3.41Å; N374-R377 VanDerWaalsContact O-N 3.13Å; N374-E378 WeakPolarHBondContact O-CG 3.35Å; N374-E378 PolarHBondContact O-N 2.86Å
375S95.4Very high96.1Very high67 Ų6751.9 Ų51.947%0.46928%0.284SS..Hα-helixtrans-60.1-39.4175.7-1780000112.1T373 R377 E378 N379T373-S375 VanDerWaalsContact C-N 3.33Å; T373-S375 PolarHBondContact OG1-N 3.48Å; S375-R377 VanDerWaalsContact C-N 3.35Å; S375-R377 PolarHBondContact O-N 2.79Å; S375-E378 PolarHBondContact O-N 3.5Å; S375-N379 PolarHBondContact O-N 2.94Å; S375-N379 PolarHBondContact O-ND2 3.15Å
376D96.3Very high96.2Very high17 Ų1751.4 Ų51.49%0.09127%0.271CS..Hα-helixtrans-64.4-39.7176-61.3-58.8000111.8P366 I372 T373 N374 N379 G380 Y381P366-D376 VanDerWaalsContact CB-OD1 3.28Å; P366-D376 WeakPolarHBondContact CB-OD1 3.41Å; P366-D376 WeakPolarHBondContact CG-OD1 3.22Å; I372-D376 HydrophobicContact CG2-CB 3.79Å; T373-D376 WeakPolarHBondContact CB-OD2 3.5Å; T373-D376 PolarHBondContact N-OD2 3.38Å; T373-D376 PolarHBondContact O-N 2.79Å; T373-D376 VanDerWaalsContact OG1-CG 3.32Å; T373-D376 PolarHBondContact OG1-N 3.44Å; T373-D376 PolarHBondContact OG1-OD2 2.84Å; N374-D376 VanDerWaalsContact C-N 3.31Å; N374-D376 PolarHBondContact O-N 3.45Å; D376-N379 CarbonylContact O-C 3.41Å; D376-N379 PolarHBondContact O-N 3.04Å; D376-G380 PolarHBondContact O-N 3.24Å; D376-Y381 CarbonylContact C-O 3.58Å; D376-Y381 WeakPolarHBondContact O-CA 3.36Å; D376-Y381 WeakPolarHBondContact O-CB 3.43Å; D376-Y381 WeakPolarHBondContact O-CD2 3.44Å; D376-Y381 PolarHBondContact O-N 2.95Å
377R96.2Very high96.3Very high97 Ų9752 Ų5237%0.36627%0.274SS..Hα-helixtrans-65.7-43.2176-68.6171.3-18082.2-6112.2I372 T373 N374 S375 N379 G380I372-R377 VanDerWaalsContact C-NH1 3.27Å; I372-R377 HydrophobicContact CG2-CG 4.22Å; I372-R377 PolarHBondContact O-NH1 2.81Å; T373-R377 WeakPolarHBondContact O-CG 3.27Å; T373-R377 PolarHBondContact O-N 2.85Å; T373-R377 VanDerWaalsContact O-N 3.16Å; T373-R377 PolarHBondContact O-NH1 2.92Å; N374-R377 WeakPolarHBondContact O-CB 3.47Å; N374-R377 PolarHBondContact O-N 3.41Å; N374-R377 VanDerWaalsContact O-N 3.13Å; S375-R377 VanDerWaalsContact C-N 3.35Å; S375-R377 PolarHBondContact O-N 2.79Å; R377-N379 PolarHBondContact O-N 2.95Å; R377-G380 PolarHBondContact O-N 3.42Å
378E96.4Very high96.3Very high162 Ų16250.2 Ų50.276%0.75727%0.272SS*.Hα-helixtrans-60.1-32.6173.8-72170.7-171.100112N374 S375 G380N374-E378 WeakPolarHBondContact O-CG 3.35Å; N374-E378 PolarHBondContact O-N 2.86Å; S375-E378 PolarHBondContact O-N 3.5Å; E378-G380 VanDerWaalsContact C-N 3.28Å; E378-G380 PolarHBondContact O-N 2.85Å
379N95.4Very high96.2Very high110 Ų11052.2 Ų52.259%0.58828%0.283SS*.THydrogen-bonded Turntrans-86.312.3173.3-73.3-89.9000113.9S375 D376 R377 Y381S375-N379 PolarHBondContact O-N 2.94Å; S375-N379 PolarHBondContact O-ND2 3.15Å; D376-N379 CarbonylContact O-C 3.41Å; D376-N379 PolarHBondContact O-N 3.04Å; R377-N379 PolarHBondContact O-N 2.95Å; N379-Y381 HydrophobicContact CB-CD2 4.05Å; N379-Y381 HydrophobicContact CB-CE2 3.96Å
380G95.5Very high96.2Very high41 Ų4155.2 Ų55.242%0.42331%0.307SS..THydrogen-bonded Turntrans91-0.9172.600000116.1D376 R377 E378 N382 Q386D376-G380 PolarHBondContact O-N 3.24Å; R377-G380 PolarHBondContact O-N 3.42Å; E378-G380 VanDerWaalsContact C-N 3.28Å; E378-G380 PolarHBondContact O-N 2.85Å; G380-N382 PolarHBondContact O-N 2.84Å; G380-Q386 PolarHBondContact O-NE2 3.31Å
381Y95.8Very high96.3Very high61 Ų6154 Ų5424%0.23930%0.298CS..  trans-93.186.7179.1-48.2-68.4000110.2P366 I372 D376 N379 Q386 P388P366-Y381 HydrophobicContact CG-CD2 3.42Å; P366-Y381 VanDerWaalsContact CG-CD2 3.42Å; P366-Y381 HydrophobicContact CG-CE2 3.55Å; P366-Y381 HydrophobicContact CG-CG 3.99Å; I372-Y381 WeakPolarHBondContact CG2-O 3.46Å; D376-Y381 CarbonylContact C-O 3.58Å; D376-Y381 WeakPolarHBondContact O-CA 3.36Å; D376-Y381 WeakPolarHBondContact O-CB 3.43Å; D376-Y381 WeakPolarHBondContact O-CD2 3.44Å; D376-Y381 PolarHBondContact O-N 2.95Å; N379-Y381 HydrophobicContact CB-CD2 4.05Å; N379-Y381 HydrophobicContact CB-CE2 3.96Å; Y381-Q386 HydrophobicContact CD1-CB 4.41Å; Y381-Q386 VanDerWaalsContact CD1-O 3.3Å; Y381-Q386 WeakPolarHBondContact CD1-O 3.48Å; Y381-P388 HydrophobicContact CE1-CG 3.84Å
382N94.8Very high96.3Very high101 Ų10154 Ų5454%0.5430%0.298SS..  trans-82.2-13.5179-68.2-48.7000113.8G380G380-N382 PolarHBondContact O-N 2.84Å
383S95.2Very high96.3Very high28 Ų2856.3 Ų56.320%0.19631%0.311CS..SBendtrans-157.2165.1178.462.40000111.8L385 Q386S383-L385 PolarHBondContact O-N 2.78Å; S383-L385 VanDerWaalsContact O-N 3.14Å; S383-Q386 PolarHBondContact O-N 3.13Å; S383-Q386 PolarHBondContact OG-OE1 3.38Å
384S96.4Very high96.4Very high2 Ų255.6 Ų55.61%0.01431%0.305CS..G310 helixtrans-56-28.8176.460.20000113.6L266 G267 T277 Q386 L387L266-S384 WeakPolarHBondContact CA-OG 3.41Å; L266-S384 WeakPolarHBondContact CB-OG 3.44Å; L266-S384 PolarHBondContact N-OG 2.9Å; G267-S384 PolarHBondContact N-OG 3.03Å; G267-S384 CarbonylContact O-C 3.51Å; G267-S384 VanDerWaalsContact O-CB 3.32Å; G267-S384 WeakPolarHBondContact O-CB 3.4Å; G267-S384 PolarHBondContact O-OG 3.15Å; T277-S384 WeakPolarHBondContact OG1-CB 3.47Å; S384-Q386 PolarHBondContact O-N 2.9Å; S384-L387 WeakPolarHBondContact O-CB 3.19Å; S384-L387 WeakPolarHBondContact O-CG 3.23Å; S384-L387 PolarHBondContact O-N 3.46Å; S384-L387 VanDerWaalsContact O-N 3.16Å
385L96.1Very high96.5Very high63 Ų6352.7 Ų52.733%0.3329%0.291SS..G310 helixtrans-60.9-27.8178.6-68.2168.6000112.6L266 G267 T269 S383L266-L385 HydrophobicContact CB-CD1 4.14Å; L266-L385 HydrophobicContact CB-CG 3.99Å; L266-L385 HydrophobicContact CD1-CD1 4.04Å; G267-L385 WeakPolarHBondContact O-CA 3.36Å; G267-L385 WeakPolarHBondContact O-CD2 2.98Å; G267-L385 PolarHBondContact O-N 3.26Å; G267-L385 VanDerWaalsContact O-N 3.14Å; T269-L385 WeakPolarHBondContact CB-O 3.34Å; T269-L385 PolarHBondContact OG1-O 3.07Å; S383-L385 PolarHBondContact O-N 2.78Å; S383-L385 VanDerWaalsContact O-N 3.14Å
386Q96.8Very high96.6Very high94 Ų9452.9 Ų52.944%0.43928%0.283SS..G310 helixtrans-93-4.3-177.6-63.6171.1-74.800113.1G380 Y381 S383 S384G380-Q386 PolarHBondContact O-NE2 3.31Å; Y381-Q386 HydrophobicContact CD1-CB 4.41Å; Y381-Q386 VanDerWaalsContact CD1-O 3.3Å; Y381-Q386 WeakPolarHBondContact CD1-O 3.48Å; S383-Q386 PolarHBondContact O-N 3.13Å; S383-Q386 PolarHBondContact OG-OE1 3.38Å; S384-Q386 PolarHBondContact O-N 2.9Å
387L97.6Very high96.6Very high16 Ų1659.1 Ų59.18%0.08431%0.31CS..SBendtrans-61.5141.6-179.5-72.3173.5000111.7P366 I372 S384 L392P366-L387 HydrophobicContact CB-CD2 3.79Å; P366-L387 HydrophobicContact CG-CD2 3.75Å; I372-L387 HydrophobicContact CD1-CD1 4.13Å; I372-L387 HydrophobicContact CD1-CD2 3.86Å; I372-L387 HydrophobicContact CD1-CG 4.08Å; S384-L387 WeakPolarHBondContact O-CB 3.19Å; S384-L387 WeakPolarHBondContact O-CG 3.23Å; S384-L387 PolarHBondContact O-N 3.46Å; S384-L387 VanDerWaalsContact O-N 3.16Å; L387-L392 HydrophobicContact CB-CD1 4.4Å; L387-L392 HydrophobicContact CB-CD2 3.89Å; L387-L392 HydrophobicContact CB-CG 4.06Å; L387-L392 HydrophobicContact CD1-CD2 4.01Å
388P97.3Very high96.6Very high39 Ų3955 Ų5525%0.25330%0.295SS..  trans-60.3139.8178-2334.2000112.1Y381 A390 T391 L392Y381-P388 HydrophobicContact CE1-CG 3.84Å; P388-A390 PolarHBondContact O-N 3.49Å; P388-T391 WeakPolarHBondContact O-CB 3.41Å; P388-T391 PolarHBondContact O-N 2.89Å; P388-L392 PolarHBondContact O-N 3.3Å; P388-L392 VanDerWaalsContact O-N 3.08Å
389D96Very high96.7Very high43 Ų4347.4 Ų47.423%0.2326%0.259CS..Hα-helixtrans-56.9-23.8176.4-83.3-57.3000112.9R270 T271 N393R270-D389 IonicContact CZ-OD2 2.64Å; R270-D389 IonicContact NE-OD1 2.84Å; R270-D389 IonicContact NE-OD2 3.33Å; R270-D389 PolarHBondContact NE-OD2 2.85Å; R270-D389 IonicContact NH2-OD2 3.16Å; R270-D389 PolarHBondContact NH2-OD2 3.02Å; T271-D389 WeakPolarHBondContact CB-OD1 3.09Å; T271-D389 PolarHBondContact N-OD1 2.79Å; T271-D389 VanDerWaalsContact N-OD1 3.11Å; T271-D389 PolarHBondContact OG1-OD1 3.36Å; D389-N393 VanDerWaalsContact O-CB 3.28Å; D389-N393 WeakPolarHBondContact O-CB 3.39Å; D389-N393 PolarHBondContact O-N 3.47Å; D389-N393 PolarHBondContact O-ND2 3.48Å
390A96.5Very high96.8Very high66 Ų6642.4 Ų42.455%0.54523%0.232SC..Hα-helixtrans-63.2-48.7171.800000112.1P388 F394P388-A390 PolarHBondContact O-N 3.49Å; A390-F394 WeakPolarHBondContact O-CB 3.04Å; A390-F394 PolarHBondContact O-N 3.29Å
391T97.9Very high96.9Very high3 Ų340.6 Ų40.62%0.01821%0.213CC..Hα-helixtrans-61.4-43.4174.2-66.20000111.1P364 P366 P368 P388 F394 A395P364-T391 WeakPolarHBondContact CB-OG1 3.39Å; P366-T391 WeakPolarHBondContact O-CG2 3.49Å; P366-T391 PolarHBondContact O-OG1 2.97Å; P368-T391 HydrophobicContact CB-CG2 4.36Å; P368-T391 HydrophobicContact CG-CG2 4.12Å; P388-T391 WeakPolarHBondContact O-CB 3.41Å; P388-T391 PolarHBondContact O-N 2.89Å; T391-F394 PolarHBondContact O-N 2.88Å; T391-A395 WeakPolarHBondContact O-CB 3.42Å; T391-A395 PolarHBondContact O-N 3.06Å
392L98.2Very high96.9Very high2 Ų240.2 Ų40.21%0.0121%0.213CC..Hα-helixtrans-68.7-42.3-179-61.8177.4000113.1T271 L272 T277 L387 P388 F394 A395 K396T271-L392 HydrophobicContact CG2-CB 3.72Å; L272-L392 HydrophobicContact CD1-CB 4.39Å; L272-L392 HydrophobicContact CD1-CD2 4.46Å; L272-L392 WeakPolarHBondContact CD1-O 3.47Å; T277-L392 HydrophobicContact CG2-CD2 3.43Å; T277-L392 VanDerWaalsContact CG2-CD2 3.43Å; L387-L392 HydrophobicContact CB-CD1 4.4Å; L387-L392 HydrophobicContact CB-CD2 3.89Å; L387-L392 HydrophobicContact CB-CG 4.06Å; L387-L392 HydrophobicContact CD1-CD2 4.01Å; P388-L392 PolarHBondContact O-N 3.3Å; P388-L392 VanDerWaalsContact O-N 3.08Å; L392-F394 VanDerWaalsContact C-N 3.31Å; L392-A395 PolarHBondContact O-N 2.87Å; L392-K396 WeakPolarHBondContact O-CB 3.32Å; L392-K396 PolarHBondContact O-N 3.3Å
393N97.4Very high97Very high70 Ų7037.8 Ų37.837%0.37420%0.2SC..Hα-helixtrans-68.7-31.9175.1-80.4-76.9000111.9T271 D389 K397T271-N393 PolarHBondContact OG1-ND2 2.89Å; D389-N393 VanDerWaalsContact O-CB 3.28Å; D389-N393 WeakPolarHBondContact O-CB 3.39Å; D389-N393 PolarHBondContact O-N 3.47Å; D389-N393 PolarHBondContact O-ND2 3.48Å; N393-K397 WeakPolarHBondContact O-CG 3.19Å; N393-K397 PolarHBondContact O-N 3.33Å
394F98Very high97Very high17 Ų1740.7 Ų40.78%0.07521%0.209CC..Hα-helixtrans-65.3-51.2171.6-168.3-73.8000111.1Y346 Y359 P364 P368 A390 T391 L392 K396 K397 H398Y346-F394 HydrophobicContact CD1-CE1 4.09Å; Y346-F394 AromaticContact CD2-CE1 3.68Å; Y346-F394 HydrophobicContact CD2-CE1 3.68Å; Y346-F394 AromaticContact CD2-CZ 3.93Å; Y346-F394 HydrophobicContact CD2-CZ 3.93Å; Y346-F394 HydrophobicContact CE1-CE1 4.32Å; Y346-F394 AromaticContact CE2-CE1 3.95Å; Y346-F394 HydrophobicContact CE2-CE1 3.95Å; Y346-F394 HydrophobicContact CE2-CZ 4.42Å; Y346-F394 AromaticContact CG-CE1 3.78Å; Y346-F394 HydrophobicContact CG-CE1 3.78Å; Y346-F394 HydrophobicContact CG-CZ 4.25Å; Y359-F394 HydrophobicContact CD1-CE2 4.16Å; Y359-F394 AromaticContact CD1-CZ 3.82Å; Y359-F394 HydrophobicContact CD1-CZ 3.82Å; Y359-F394 HydrophobicContact CD2-CE2 4.47Å; Y359-F394 HydrophobicContact CD2-CZ 4.43Å; Y359-F394 AromaticContact CE1-CE2 3.62Å; Y359-F394 HydrophobicContact CE1-CE2 3.62Å; Y359-F394 AromaticContact CE1-CZ 3.75Å; Y359-F394 HydrophobicContact CE1-CZ 3.75Å; Y359-F394 HydrophobicContact CE2-CE2 4Å; Y359-F394 HydrophobicContact CE2-CZ 4.4Å; Y359-F394 HydrophobicContact CG-CZ 4.17Å; Y359-F394 AromaticContact CZ-CE2 3.55Å; P364-F394 HydrophobicContact CG-CB 3.9Å; P364-F394 HydrophobicContact CG-CD2 3.87Å; P364-F394 HydrophobicContact CG-CG 4.02Å; P368-F394 HydrophobicContact CB-CB 4.26Å; P368-F394 HydrophobicContact CB-CD1 3.52Å; P368-F394 HydrophobicContact CB-CE1 4.27Å; P368-F394 HydrophobicContact CB-CG 4.22Å; P368-F394 HydrophobicContact CG-CB 3.86Å; P368-F394 HydrophobicContact CG-CD1 3.42Å; P368-F394 VanDerWaalsContact CG-CD1 3.42Å; P368-F394 HydrophobicContact CG-CE1 4.14Å; P368-F394 HydrophobicContact CG-CG 3.75Å; A390-F394 WeakPolarHBondContact O-CB 3.04Å; A390-F394 PolarHBondContact O-N 3.29Å; T391-F394 PolarHBondContact O-N 2.88Å; L392-F394 VanDerWaalsContact C-N 3.31Å; F394-K396 VanDerWaalsContact C-N 3.28Å; F394-K396 PolarHBondContact O-N 3.35Å; F394-K397 PolarHBondContact O-N 3.04Å; F394-K397 VanDerWaalsContact O-N 3.07Å; F394-H398 HydrophobicContact CD1-CB 3.9Å; F394-H398 AromaticContact CD1-CG 3.96Å; F394-H398 AromaticContact CD1-ND1 3.37Å; F394-H398 WeakPolarHBondContact CD1-ND1 3.1Å; F394-H398 AromaticContact CD2-CE1 3.92Å; F394-H398 AromaticContact CD2-ND1 3.59Å; F394-H398 HydrophobicContact CE1-CB 3.59Å; F394-H398 AromaticContact CE1-CG 3.63Å; F394-H398 AromaticContact CE1-ND1 3.32Å; F394-H398 VanDerWaalsContact CE1-ND1 3.32Å; F394-H398 WeakPolarHBondContact CE1-ND1 3.31Å; F394-H398 AromaticContact CE2-CE1 3.73Å; F394-H398 AromaticContact CE2-ND1 3.54Å; F394-H398 AromaticContact CG-ND1 3.51Å; F394-H398 HydrophobicContact CZ-CB 4.29Å; F394-H398 AromaticContact CZ-CE1 3.89Å; F394-H398 AromaticContact CZ-CG 3.88Å; F394-H398 AromaticContact CZ-ND1 3.41Å; F394-H398 WeakPolarHBondContact CZ-ND1 3.39Å; F394-H398 WeakPolarHBondContact O-CB 3.21Å; F394-H398 PolarHBondContact O-N 2.92Å; F394-H398 PolarHBondContact O-ND1 2.8Å
395A97.8Very high97.1Very high8 Ų840.8 Ų40.87%0.06621%0.21CC..Hα-helixtrans-56.4-42.917800000111.7P368 T391 L392 K397 H398P368-A395 HydrophobicContact CB-CB 4.1Å; T391-A395 WeakPolarHBondContact O-CB 3.42Å; T391-A395 PolarHBondContact O-N 3.06Å; L392-A395 PolarHBondContact O-N 2.87Å; A395-K397 VanDerWaalsContact C-N 3.29Å; A395-K397 PolarHBondContact O-N 3.35Å; A395-H398 PolarHBondContact O-N 3.29Å
396K97.5Very high97Very high70 Ų7043.2 Ų43.230%0.30422%0.223SC..Hα-helixtrans-60-34.7176.7-178.4164.6174.2162.10113.8E205 L207 W210 L272 L392 F394E205-K396 WeakPolarHBondContact OE1-CE 3.32Å; E205-K396 IonicContact OE1-NZ 3.42Å; E205-K396 PolarHBondContact OE1-NZ 3.36Å; L207-K396 HydrophobicContact CD1-CG 4.49Å; W210-K396 PolarHBondContact NE1-O 3.03Å; L272-K396 HydrophobicContact CD1-CB 4.2Å; L272-K396 HydrophobicContact CD2-CB 4.25Å; L272-K396 HydrophobicContact CD2-CD 4.12Å; L272-K396 HydrophobicContact CD2-CG 4.34Å; L272-K396 HydrophobicContact CG-CB 4.34Å; L272-K396 HydrophobicContact CG-CD 4.49Å; L392-K396 WeakPolarHBondContact O-CB 3.32Å; L392-K396 PolarHBondContact O-N 3.3Å; F394-K396 VanDerWaalsContact C-N 3.28Å; F394-K396 PolarHBondContact O-N 3.35Å
397K95.8Very high96.8Very high149 Ų14939 Ų3965%0.64820%0.204SC*.Hα-helixtrans-87.6-29.3179.6-71.6-176.1176-1690113.8N393 F394 A395 P399N393-K397 WeakPolarHBondContact O-CG 3.19Å; N393-K397 PolarHBondContact O-N 3.33Å; F394-K397 PolarHBondContact O-N 3.04Å; F394-K397 VanDerWaalsContact O-N 3.07Å; A395-K397 VanDerWaalsContact C-N 3.29Å; A395-K397 PolarHBondContact O-N 3.35Å; K397-P399 VanDerWaalsContact O-CD 3.27Å; K397-P399 WeakPolarHBondContact O-CD 3.49Å
398H96.7Very high96.5Very high11 Ų1144.8 Ų44.85%0.05123%0.225CC..  trans-120.656-171-56110.7000113.6Y346 E348 F394 A395 L400Y346-H398 HydrophobicContact CD1-CB 4.21Å; Y346-H398 HydrophobicContact CG-CB 4.36Å; E348-H398 WeakPolarHBondContact CG-NE2 3.28Å; E348-H398 IonicContact OE1-NE2 3.95Å; E348-H398 PolarHBondContact OE1-NE2 2.75Å; F394-H398 HydrophobicContact CD1-CB 3.9Å; F394-H398 AromaticContact CD1-CG 3.96Å; F394-H398 AromaticContact CD1-ND1 3.37Å; F394-H398 WeakPolarHBondContact CD1-ND1 3.1Å; F394-H398 AromaticContact CD2-CE1 3.92Å; F394-H398 AromaticContact CD2-ND1 3.59Å; F394-H398 HydrophobicContact CE1-CB 3.59Å; F394-H398 AromaticContact CE1-CG 3.63Å; F394-H398 AromaticContact CE1-ND1 3.32Å; F394-H398 VanDerWaalsContact CE1-ND1 3.32Å; F394-H398 WeakPolarHBondContact CE1-ND1 3.31Å; F394-H398 AromaticContact CE2-CE1 3.73Å; F394-H398 AromaticContact CE2-ND1 3.54Å; F394-H398 AromaticContact CG-ND1 3.51Å; F394-H398 HydrophobicContact CZ-CB 4.29Å; F394-H398 AromaticContact CZ-CE1 3.89Å; F394-H398 AromaticContact CZ-CG 3.88Å; F394-H398 AromaticContact CZ-ND1 3.41Å; F394-H398 WeakPolarHBondContact CZ-ND1 3.39Å; F394-H398 WeakPolarHBondContact O-CB 3.21Å; F394-H398 PolarHBondContact O-N 2.92Å; F394-H398 PolarHBondContact O-ND1 2.8Å; A395-H398 PolarHBondContact O-N 3.29Å; H398-L400 PolarHBondContact O-N 2.9Å
399P97.3Very high96.3Very high1 Ų143.2 Ų43.21%0.00622%0.215CC..  trans-72.2-16.4176.433.5-38.6000112.8A209 W210 F279 Q280 K281 K397A209-P399 HydrophobicContact CB-CG 4.37Å; A209-P399 VanDerWaalsContact O-CG 3.27Å; A209-P399 WeakPolarHBondContact O-CG 3.46Å; W210-P399 HydrophobicContact CG-CB 4.39Å; W210-P399 HydrophobicContact CG-CG 4.22Å; F279-P399 HydrophobicContact CD1-CB 3.86Å; F279-P399 HydrophobicContact CE1-CB 3.9Å; Q280-P399 CarbonylContact C-O 3.56Å; Q280-P399 WeakPolarHBondContact CA-O 3.33Å; K281-P399 PolarHBondContact N-O 3.09Å; K397-P399 VanDerWaalsContact O-CD 3.27Å; K397-P399 WeakPolarHBondContact O-CD 3.49Å
400L98.1Very high96.1Very high6 Ų641.9 Ų41.93%0.03121%0.208CC..EExtended strand (participates in β ladder)trans-97.6127.9-174.6179.560.1000111.4E246 K281 K347 W356 H398E246-L400 HydrophobicContact CB-CD2 4.05Å; E246-L400 HydrophobicContact CG-CD2 4.05Å; K281-L400 HydrophobicContact CG-CD1 4.11Å; K281-L400 WeakPolarHBondContact O-CA 3.29Å; K347-L400 HydrophobicContact CB-CB 4.42Å; K347-L400 HydrophobicContact CB-CD2 4.28Å; K347-L400 HydrophobicContact CB-CG 4.06Å; K347-L400 HydrophobicContact CD-CD2 3.76Å; K347-L400 HydrophobicContact CD-CG 4.22Å; K347-L400 PolarHBondContact N-O 2.81Å; W356-L400 HydrophobicContact CZ3-CD2 4.48Å; H398-L400 PolarHBondContact O-N 2.9Å
401M98.1Very high96Very high3 Ų338.8 Ų38.82%0.01518%0.182CC..EExtended strand (participates in β ladder)trans-77.2147.9169.9-50.5-46.4-62.900111.2Q280 K281 A282 V341 F342 Y346Q280-M401 HydrophobicContact CB-SD 4.47Å; K281-M401 PolarHBondContact O-N 2.91Å; A282-M401 HydrophobicContact CB-CB 4.12Å; A282-M401 HydrophobicContact CB-CG 4.14Å; V341-M401 HydrophobicContact CG1-CB 4.07Å; V341-M401 HydrophobicContact CG1-CG 4.41Å; V341-M401 WeakPolarHBondContact O-CE 3.3Å; F342-M401 HydrophobicContact CD1-CG 3.77Å; F342-M401 HydrophobicContact CD1-SD 4.25Å; F342-M401 HydrophobicContact CE1-CG 4.19Å; Y346-M401 HydrophobicContact CD1-CE 3.95Å; Y346-M401 HydrophobicContact CD1-SD 3.93Å; Y346-M401 HydrophobicContact CE1-CE 4.03Å; Y346-M401 HydrophobicContact CE1-SD 4.09Å; Y346-M401 HydrophobicContact CG-CE 4.38Å
402E96.3Very high95.7Very high52 Ų5238.8 Ų38.824%0.24318%0.182CC..EExtended strand (participates in β ladder)trans-74.1-43175.3170.369.2165.600111.8S345 K347 R358S345-E402 WeakPolarHBondContact O-CB 3.35Å; S345-E402 PolarHBondContact O-N 2.88Å; K347-E402 HydrophobicContact CB-CB 4.38Å; K347-E402 WeakPolarHBondContact CD-OE2 3.4Å; K347-E402 VanDerWaalsContact CE-OE2 3.25Å; K347-E402 WeakPolarHBondContact CE-OE2 3.5Å; K347-E402 VanDerWaalsContact CG-OE2 3.27Å; K347-E402 WeakPolarHBondContact CG-OE2 3.33Å; K347-E402 IonicContact NZ-OE2 3.85Å; K347-E402 PolarHBondContact NZ-OE2 2.93Å; R358-E402 HydrophobicContact CB-CB 4.43Å; R358-E402 HydrophobicContact CB-CG 3.73Å; R358-E402 WeakPolarHBondContact CB-OE1 3.29Å; R358-E402 HydrophobicContact CG-CB 4.43Å; R358-E402 HydrophobicContact CG-CG 3.98Å; R358-E402 VanDerWaalsContact N-CD 3.33Å; R358-E402 PolarHBondContact N-OE1 2.9Å; R358-E402 PolarHBondContact N-OE2 2.83Å
403D96.8Very high95.4Very high51 Ų5138.9 Ų38.927%0.27318%0.183SC..EExtended strand (participates in β ladder)trans-80.4162-176.2-53.2-54.3000110.6V341 S345 R358V341-D403 HydrophobicContact CG1-CB 4.25Å; V341-D403 WeakPolarHBondContact CG1-O 3.39Å; S345-D403 PolarHBondContact N-OD2 3.48Å; R358-D403 IonicContact CZ-OD1 2.7Å; R358-D403 IonicContact NH2-OD1 2.79Å; R358-D403 PolarHBondContact NH2-OD1 2.88Å; R358-D403 IonicContact NH2-OD2 2.76Å
404K95.5Very high95.1Very high89 Ų8939.8 Ų39.839%0.38718%0.183SC..EExtended strand (participates in β ladder)trans-129.1141.9-171.952.6170.7169.8164.50112.7R283 E285 L406R283-K404 HydrophobicContact CB-CB 4.09Å; E285-K404 HydrophobicContact CB-CD 4.16Å; E285-K404 WeakPolarHBondContact OE1-CD 3.48Å; E285-K404 IonicContact OE1-NZ 2.64Å; E285-K404 PolarHBondContact OE1-NZ 2.85Å; E285-K404 IonicContact OE2-NZ 2.77Å; E285-K404 PolarHBondContact OE2-NZ 3.04Å; K404-L406 HydrophobicContact CD-CD2 3.75Å; K404-L406 HydrophobicContact CG-CD2 4.01Å; K404-L406 HydrophobicContact CG-CG 4.45Å; K404-L406 PolarHBondContact O-N 2.9Å
405A96.9Very high94.6Very high3 Ų341.5 Ų41.53%0.02521%0.206CC..EExtended strand (participates in β ladder)trans-77.1114.6171.600000108.7R283 L284 E285 Y333 V338R283-A405 PolarHBondContact O-N 2.75Å; L284-A405 HydrophobicContact CD1-CB 3.95Å; E285-A405 PolarHBondContact N-O 2.8Å; Y333-A405 HydrophobicContact CD1-CB 4.3Å; V338-A405 HydrophobicContact CG2-CB 4.18Å
406L94.8Very high94.4Very high115 Ų11542.9 Ų42.960%0.60221%0.214SC*.EExtended strand (participates in β ladder)trans-93.9131.4-175.5-67.2175.1000111.4E285 K404E285-L406 HydrophobicContact CB-CD2 4.37Å; E285-L406 WeakPolarHBondContact OE2-CD2 3.26Å; K404-L406 HydrophobicContact CD-CD2 3.75Å; K404-L406 HydrophobicContact CG-CD2 4.01Å; K404-L406 HydrophobicContact CG-CG 4.45Å; K404-L406 PolarHBondContact O-N 2.9Å
407G92.9Very high94.2Very high5 Ų541 Ų415%0.05221%0.207CC..EExtended strand (participates in β ladder)trans-130.8133.9172.500000110.1E285 C286 S287 C331 Y333E285-G407 PolarHBondContact O-N 2.78Å; C286-G407 WeakPolarHBondContact CA-O 3.21Å; S287-G407 PolarHBondContact N-O 2.74Å; C331-G407 PolarHBondContact SG-O 2.89Å; C331-G407 VanDerWaalsContact SG-O 3.4Å; Y333-G407 VanDerWaalsContact CE1-N 3.28Å
408R91Very high94.3Very high137 Ų13734 Ų3452%0.51718%0.176SC..  trans-93.3137.9168.4-71.1-178.6173.7-84.66109.1E290 L410E290-R408 IonicContact OE1-CZ 3.21Å; E290-R408 VanDerWaalsContact OE1-CZ 3.23Å; E290-R408 IonicContact OE1-NH1 2.9Å; E290-R408 PolarHBondContact OE1-NH1 2.8Å; E290-R408 IonicContact OE1-NH2 3.82Å; E290-R408 PolarHBondContact OE1-NH2 2.9Å; E290-R408 IonicContact OE2-CZ 2.78Å; E290-R408 IonicContact OE2-NH1 3.89Å; E290-R408 PolarHBondContact OE2-NH1 3.19Å; R408-L410 PolarHBondContact O-N 3.04Å
409P92.4Very high94.4Very high7 Ų734.7 Ų34.75%0.04518%0.181CC..EExtended strand (participates in β ladder)trans-57.6126173.7-27.534.5000111.9L21 S287 L288 F295 A329 V330L21-P409 WeakPolarHBondContact CD1-O 3.24Å; L21-P409 HydrophobicContact CD2-CB 4.11Å; S287-P409 WeakPolarHBondContact O-CD 3.28Å; L288-P409 HydrophobicContact CD1-CG 4.29Å; L288-P409 HydrophobicContact CD2-CG 4.3Å; L288-P409 HydrophobicContact CG-CG 3.95Å; F295-P409 HydrophobicContact CD2-CG 4.14Å; F295-P409 HydrophobicContact CE2-CG 3.87Å; A329-P409 HydrophobicContact CB-CB 4.27Å; A329-P409 HydrophobicContact CB-CG 4.26Å; V330-P409 CarbonylContact O-C 3.58Å; V330-P409 WeakPolarHBondContact O-CA 3.28Å
410L93Very high94.4Very high15 Ų1537.7 Ų37.78%0.07920%0.195CC..EExtended strand (participates in β ladder)trans-80.8-37.3167.8-58.5175.5000110.7L21 Y315 V330 Q332 R408 I451 A456L21-L410 WeakPolarHBondContact CD1-O 3.1Å; Y315-L410 HydrophobicContact CD1-CD1 4.31Å; Y315-L410 HydrophobicContact CE1-CD1 3.74Å; V330-L410 PolarHBondContact O-N 2.88Å; Q332-L410 HydrophobicContact CB-CD1 4.01Å; Q332-L410 HydrophobicContact CG-CD1 3.97Å; Q332-L410 HydrophobicContact CG-CD2 4.41Å; Q332-L410 HydrophobicContact CG-CG 4.4Å; R408-L410 PolarHBondContact O-N 3.04Å; L410-I451 HydrophobicContact CB-CD1 4.15Å; L410-I451 HydrophobicContact CD1-CD1 4.07Å; L410-I451 HydrophobicContact CD1-CG1 4.31Å; L410-I451 HydrophobicContact CD1-CG2 4.49Å; L410-A456 WeakPolarHBondContact O-CB 3.21Å
411L93.8Very high94.4Very high1 Ų138 Ų381%0.00520%0.196CC..EExtended strand (participates in β ladder)trans-130.1140.5179.7178.963.2000109.1P25 A329 V330 F418 I439 V449 A456 V458P25-L411 HydrophobicContact CG-CD1 3.41Å; P25-L411 VanDerWaalsContact CG-CD1 3.41Å; A329-L411 WeakPolarHBondContact CA-O 3.24Å; V330-L411 HydrophobicContact CB-CB 4.25Å; V330-L411 HydrophobicContact CG2-CB 4.26Å; V330-L411 HydrophobicContact CG2-CD2 4.28Å; V330-L411 PolarHBondContact N-O 2.88Å; L411-F418 HydrophobicContact CD2-CE2 3.71Å; L411-F418 HydrophobicContact CD2-CZ 3.82Å; L411-F418 HydrophobicContact CG-CE2 4.22Å; L411-F418 HydrophobicContact CG-CZ 4.45Å; L411-I439 HydrophobicContact CD2-CD1 3.41Å; L411-I439 VanDerWaalsContact CD2-CD1 3.41Å; L411-V449 HydrophobicContact CD2-CG1 4.42Å; L411-V449 HydrophobicContact CD2-CG2 4.16Å; L411-A456 HydrophobicContact CB-CB 4.3Å; L411-A456 HydrophobicContact CD1-CB 4.42Å; L411-V458 HydrophobicContact CD1-CG2 4.11Å
412L91.8Very high94.3Very high3 Ų337.8 Ų37.82%0.01620%0.195CC..EExtended strand (participates in β ladder)trans-143.6119.1178.1-175.273000110.2L21 W23 N24 P25 L288 F295 V327 S328 A329L21-L412 HydrophobicContact CD2-CB 4.24Å; W23-L412 HydrophobicContact CD2-CD2 3.61Å; W23-L412 HydrophobicContact CE3-CD2 4.21Å; W23-L412 HydrophobicContact CG-CD2 3.93Å; W23-L412 HydrophobicContact CH2-CD2 4.24Å; W23-L412 HydrophobicContact CZ2-CD2 3.61Å; N24-L412 VanDerWaalsContact CA-O 3.29Å; N24-L412 WeakPolarHBondContact CA-O 3.21Å; N24-L412 PolarHBondContact N-O 3.44Å; P25-L412 WeakPolarHBondContact CD-O 3.43Å; L288-L412 HydrophobicContact CD1-CD2 4.2Å; F295-L412 HydrophobicContact CE1-CD1 3.59Å; F295-L412 HydrophobicContact CE2-CD1 4.14Å; F295-L412 HydrophobicContact CZ-CD1 3.31Å; V327-L412 HydrophobicContact CG1-CD1 3.51Å; V327-L412 HydrophobicContact CG1-CG 4.07Å; S328-L412 WeakPolarHBondContact O-CA 3.39Å; A329-L412 HydrophobicContact CB-CD1 3.9Å
413T91.3Very high94.4Very high4 Ų435.3 Ų35.33%0.02518%0.184CC..EExtended strand (participates in β ladder)trans-132.6136.1-174-50.70000110.5N24 V327 S328 V416 F418N24-T413 WeakPolarHBondContact OD1-CG2 3.32Å; V327-T413 WeakPolarHBondContact CA-O 3.43Å; V327-T413 WeakPolarHBondContact CG1-O 3.49Å; S328-T413 PolarHBondContact N-O 3.49Å; S328-T413 PolarHBondContact O-N 3.3Å; T413-V416 HydrophobicContact CG2-CB 3.75Å; T413-V416 HydrophobicContact CG2-CG2 3.73Å; T413-F418 HydrophobicContact CG2-CZ 4.43Å; T413-F418 WeakPolarHBondContact OG1-CZ 3.22Å
414K90.5Very high94.4Very high88 Ų8833.1 Ų33.138%0.38317%0.172SC..EExtended strand (participates in β ladder)trans-100.9141.8-178.8-63.5-173.2175.2-170.50110.6N24 V325 V327 V416N24-K414 PolarHBondContact OD1-N 3.04Å; N24-K414 PolarHBondContact OD1-O 2.69Å; V325-K414 HydrophobicContact CG1-CB 4.09Å; V327-K414 HydrophobicContact CG1-CG 4.44Å; V327-K414 HydrophobicContact CG2-CG 4.27Å; K414-V416 PolarHBondContact O-N 3.14Å; K414-V416 VanDerWaalsContact O-N 3.14Å
415G88.6Confident94.4Very high54 Ų5432.9 Ų32.956%0.55717%0.168SC*.SBendtrans67.27.8177.200000115.2D326D326-G415 PolarHBondContact O-N 2.91Å
416V92.4Very high94.3Very high37 Ų3733.5 Ų33.522%0.22417%0.172CC..  trans-121.8121.4176.4-176.70000108.1S328 T413 K414 F418 T441S328-V416 WeakPolarHBondContact CB-O 3.33Å; S328-V416 PolarHBondContact OG-O 2.98Å; T413-V416 HydrophobicContact CG2-CB 3.75Å; T413-V416 HydrophobicContact CG2-CG2 3.73Å; K414-V416 PolarHBondContact O-N 3.14Å; K414-V416 VanDerWaalsContact O-N 3.14Å; V416-F418 HydrophobicContact CB-CE1 4.41Å; V416-F418 HydrophobicContact CG1-CD1 3.91Å; V416-F418 HydrophobicContact CG1-CE1 3.71Å; V416-T441 HydrophobicContact CG1-CG2 3.72Å
417N94.9Very high94.2Very high31 Ų3131.9 Ų31.917%0.16617%0.17CC..  trans-100.9100.1-175-71.5-1.9000109.5D326 S328 T441 A442D326-N417 WeakPolarHBondContact CB-OD1 3.08Å; D326-N417 PolarHBondContact OD2-ND2 2.85Å; S328-N417 WeakPolarHBondContact OG-CA 3.46Å; N417-T441 CarbonylContact O-C 3.43Å; N417-T441 WeakPolarHBondContact O-CA 3.04Å; N417-A442 HydrophobicContact CB-CB 4.11Å; N417-A442 PolarHBondContact O-N 3.03Å
418F97.9Very high94.2Very high0 Ų032 Ų320%017%0.171CC..EExtended strand (participates in β ladder)trans-70.6138.1177.8-60.8-24.8000111I317 H319 S328 V330 L411 T413 V416 I439 G440 T441I317-F418 HydrophobicContact CD1-CB 3.94Å; I317-F418 HydrophobicContact CG1-CB 4.36Å; I317-F418 HydrophobicContact CG2-CB 3.68Å; H319-F418 PolarHBondContact CE1-O 2.93Å; H319-F418 PolarHBondContact NE2-O 3.4Å; S328-F418 PolarHBondContact OG-N 3.42Å; V330-F418 HydrophobicContact CG2-CD2 4.1Å; V330-F418 HydrophobicContact CG2-CE2 4.13Å; L411-F418 HydrophobicContact CD2-CE2 3.71Å; L411-F418 HydrophobicContact CD2-CZ 3.82Å; L411-F418 HydrophobicContact CG-CE2 4.22Å; L411-F418 HydrophobicContact CG-CZ 4.45Å; T413-F418 HydrophobicContact CG2-CZ 4.43Å; T413-F418 WeakPolarHBondContact OG1-CZ 3.22Å; V416-F418 HydrophobicContact CB-CE1 4.41Å; V416-F418 HydrophobicContact CG1-CD1 3.91Å; V416-F418 HydrophobicContact CG1-CE1 3.71Å; F418-I439 HydrophobicContact CB-CG2 3.81Å; F418-I439 HydrophobicContact CD1-CG2 3.56Å; F418-I439 HydrophobicContact CD2-CG2 3.81Å; F418-I439 HydrophobicContact CE1-CG2 3.96Å; F418-I439 HydrophobicContact CE2-CD1 4.34Å; F418-I439 HydrophobicContact CE2-CG2 4.22Å; F418-I439 HydrophobicContact CG-CG2 3.47Å; F418-I439 VanDerWaalsContact CG-CG2 3.47Å; F418-I439 HydrophobicContact CZ-CG2 4.27Å; F418-G440 CarbonylContact C-O 3.55Å; F418-G440 WeakPolarHBondContact CA-O 3.24Å; F418-T441 HydrophobicContact CD1-CG2 4.14Å; F418-T441 HydrophobicContact CE1-CG2 4.49Å
419T97.4Very high94.3Very high26 Ų2628.3 Ų28.316%0.1616%0.162CC..EExtended strand (participates in β ladder)trans-120-33.8-173.458.50000114.5G440 A442 V471T419-G440 PolarHBondContact N-O 2.68Å; T419-G440 PolarHBondContact OG1-O 3.48Å; T419-A442 HydrophobicContact CG2-CB 3.83Å; T419-V471 WeakPolarHBondContact CB-O 3.46Å; T419-V471 PolarHBondContact OG1-O 3.08Å
420K97.6Very high94.2Very high65 Ų6531.1 Ų31.128%0.28318%0.176SC..EExtended strand (participates in β ladder)trans-146.3152.9-174.3-64.5-69.4160.5-980111.2I317 G440 V471 D472 L474I317-K420 WeakPolarHBondContact CD1-O 2.97Å; K420-G440 PolarHBondContact O-N 2.88Å; K420-V471 HydrophobicContact CB-CG1 4.15Å; K420-V471 HydrophobicContact CG-CG1 4.22Å; K420-V471 WeakPolarHBondContact CG-O 3.44Å; K420-D472 WeakPolarHBondContact CE-O 3.41Å; K420-L474 HydrophobicContact CB-CB 3.77Å; K420-L474 HydrophobicContact CB-CD2 4.21Å; K420-L474 HydrophobicContact CG-CB 4.49Å
421L97.6Very high94.1Very high11 Ų1138.8 Ų38.86%0.05821%0.212CC..EExtended strand (participates in β ladder)trans-137.5136.4-176.5-179.465.7000111F302 Y315 I317 V330 V423 L437 F438 I439F302-L421 HydrophobicContact CB-CB 4.44Å; F302-L421 HydrophobicContact CB-CD2 3.99Å; F302-L421 HydrophobicContact CB-CG 4.05Å; F302-L421 WeakPolarHBondContact CD2-O 3.48Å; Y315-L421 VanDerWaalsContact CB-CD2 3.43Å; Y315-L421 HydrophobicContact CG-CD2 4.44Å; I317-L421 HydrophobicContact CD1-CB 3.76Å; I317-L421 HydrophobicContact CG1-CB 4.26Å; V330-L421 HydrophobicContact CG1-CD2 4.46Å; L421-V423 HydrophobicContact CD1-CG2 4.22Å; L421-V423 HydrophobicContact CD2-CG2 4.22Å; L421-V423 HydrophobicContact CG-CG2 4.08Å; L421-L437 HydrophobicContact CD1-CB 4.09Å; L421-L437 HydrophobicContact CD1-CD2 4.24Å; L421-L437 HydrophobicContact CD1-CG 4.03Å; L421-F438 WeakPolarHBondContact CA-O 3.06Å; L421-I439 HydrophobicContact CD1-CG1 3.83Å
422A98Very high94.1Very high0 Ų045.2 Ų45.20%024%0.236CC..EExtended strand (participates in β ladder)trans-129151.7160.400000109.6F302 F438 L474 I476 L483F302-A422 HydrophobicContact CD2-CB 4.4Å; F302-A422 HydrophobicContact CE2-CB 4.18Å; A422-F438 HydrophobicContact CB-CB 4.36Å; A422-F438 PolarHBondContact N-O 3.13Å; A422-F438 PolarHBondContact O-N 3.38Å; A422-L474 HydrophobicContact CB-CD2 4.06Å; A422-L474 HydrophobicContact CB-CG 4.12Å; A422-I476 HydrophobicContact CB-CB 4.19Å; A422-I476 HydrophobicContact CB-CG2 4.03Å; A422-L483 HydrophobicContact CB-CD1 4.04Å
423V97.6Very high94.1Very high0 Ų048.1 Ų48.10%026%0.26CS..EExtended strand (participates in β ladder)trans-134.7126.2-179.7-171.40000110.3F302 L304 Y315 L421 N435 M436 L437 H478F302-V423 HydrophobicContact CB-CG2 4.37Å; F302-V423 HydrophobicContact CD1-CB 3.65Å; F302-V423 HydrophobicContact CD1-CG2 3.67Å; F302-V423 HydrophobicContact CE1-CB 3.7Å; F302-V423 HydrophobicContact CE1-CG2 4.24Å; F302-V423 VanDerWaalsContact CE1-O 3.3Å; F302-V423 WeakPolarHBondContact CE1-O 3.26Å; F302-V423 HydrophobicContact CG-CB 4.49Å; F302-V423 HydrophobicContact CG-CG2 4.16Å; F302-V423 WeakPolarHBondContact CZ-O 3.23Å; L304-V423 HydrophobicContact CD1-CG1 4.4Å; L304-V423 HydrophobicContact CD2-CG1 3.99Å; Y315-V423 HydrophobicContact CD2-CG2 4Å; Y315-V423 HydrophobicContact CE2-CG1 4.34Å; Y315-V423 HydrophobicContact CG-CG2 4.14Å; L421-V423 HydrophobicContact CD1-CG2 4.22Å; L421-V423 HydrophobicContact CD2-CG2 4.22Å; L421-V423 HydrophobicContact CG-CG2 4.08Å; V423-N435 HydrophobicContact CG1-CB 4.22Å; V423-M436 VanDerWaalsContact CA-O 3.31Å; V423-M436 WeakPolarHBondContact CA-O 3.42Å; V423-L437 HydrophobicContact CG1-CD1 4.11Å; V423-L437 HydrophobicContact CG2-CD1 4.37Å; V423-L437 HydrophobicContact CG2-CG 4.09Å; V423-H478 PolarHBondContact O-CE1 2.86Å
424D96.7Very high94.3Very high5 Ų548.7 Ų48.73%0.02726%0.262CS..EExtended strand (participates in β ladder)trans-98.8153.5165.3-157.49.2000110.4N435 M436 F438 I476 H478 K481 L496 Y515D424-N435 WeakPolarHBondContact O-CA 3.45Å; D424-M436 PolarHBondContact N-O 2.62Å; D424-M436 PolarHBondContact O-N 3.28Å; D424-F438 HydrophobicContact CB-CE2 4.31Å; D424-I476 HydrophobicContact CB-CD1 3.75Å; D424-H478 IonicContact OD1-CE1 3.37Å; D424-H478 IonicContact OD1-CG 2.77Å; D424-H478 IonicContact OD1-ND1 3.77Å; D424-H478 PolarHBondContact OD1-ND1 2.99Å; D424-K481 IonicContact OD1-NZ 2.83Å; D424-K481 IonicContact OD2-NZ 3.55Å; D424-K481 PolarHBondContact OD2-NZ 2.85Å; D424-L496 HydrophobicContact CB-CD1 4.47Å; D424-Y515 VanDerWaalsContact CB-OH 3.29Å; D424-Y515 WeakPolarHBondContact CB-OH 3.29Å; D424-Y515 PolarHBondContact OD2-OH 3.16Å
425R95.4Very high94.6Very high84 Ų8445.9 Ų45.932%0.31725%0.251SS..EExtended strand (participates in β ladder)trans-111112166.8-174179.2-65.4129.2-8.2108.2L304 P305 A433 Y434 N435L304-R425 HydrophobicContact CD1-CB 4.42Å; P305-R425 PolarHBondContact O-NH1 2.8Å; P305-R425 PolarHBondContact O-NH2 3.49Å; R425-A433 HydrophobicContact CG-CB 4.17Å; R425-Y434 WeakPolarHBondContact CA-O 3.26Å; R425-N435 PolarHBondContact NE-OD1 3.33Å
426V94.4Very high95Very high15 Ų1543.3 Ų43.39%0.09123%0.225CC..EExtended strand (participates in β ladder)trans-121.2134.7-16951.60000110.3Y434 M436 P514 Y515V426-Y434 PolarHBondContact N-O 2.68Å; V426-Y434 PolarHBondContact O-N 3.47Å; V426-M436 HydrophobicContact CG1-CB 4.11Å; V426-P514 HydrophobicContact CG1-CB 3.62Å; V426-P514 HydrophobicContact CG1-CG 3.58Å; V426-P514 HydrophobicContact CG2-CB 4.06Å; V426-Y515 HydrophobicContact CB-CE1 3.95Å; V426-Y515 HydrophobicContact CG1-CE1 4.37Å; V426-Y515 HydrophobicContact CG2-CD1 3.8Å; V426-Y515 HydrophobicContact CG2-CE1 3.75Å
427S93.3Very high95.3Very high82 Ų8241.6 Ų41.657%0.57321%0.214SC*.EExtended strand (participates in β ladder)trans-86.7128.2175.1-58.60000110.6R432S427-R432 WeakPolarHBondContact CA-O 3.3Å
428G92.4Very high95.5Very high7 Ų740.1 Ų40.17%0.07221%0.207CC..  trans-75.3172169.800000112.5D430 Q431 R432G428-D430 PolarHBondContact O-N 3.5Å; G428-Q431 WeakPolarHBondContact O-CA 3.43Å; G428-Q431 PolarHBondContact O-N 3.32Å; G428-R432 PolarHBondContact N-O 3.21Å
429L93.8Very high95.5Very high60 Ų6040.1 Ų40.131%0.31421%0.207SC..THydrogen-bonded Turntrans-64.6-17.2172.7-65-173.3000113.1Q431 A517 I528 L538 Q540L429-Q431 PolarHBondContact O-N 3.25Å; L429-A517 HydrophobicContact CD1-CB 3.69Å; L429-A517 HydrophobicContact CG-CB 4.5Å; L429-I528 HydrophobicContact CD2-CD1 3.94Å; L429-I528 HydrophobicContact CD2-CG1 4.29Å; L429-I528 HydrophobicContact CD2-CG2 3.98Å; L429-I528 HydrophobicContact CG-CD1 3.95Å; L429-L538 HydrophobicContact CD1-CB 3.63Å; L429-L538 HydrophobicContact CD2-CD1 4.48Å; L429-Q540 HydrophobicContact CB-CB 4.25Å; L429-Q540 HydrophobicContact CD1-CB 3.82Å; L429-Q540 HydrophobicContact CG-CB 4.09Å
430D90.6Very high95.6Very high65 Ų6538.9 Ų38.935%0.34820%0.199SC..THydrogen-bonded Turntrans-80.28170.673.7-19.1000113.3G428 R432 Y434G428-D430 PolarHBondContact O-N 3.5Å; D430-R432 PolarHBondContact O-N 3.03Å; D430-R432 VanDerWaalsContact O-N 3.13Å; D430-R432 WeakPolarHBondContact OD1-CB 3.28Å; D430-R432 PolarHBondContact OD1-N 2.93Å; D430-R432 VanDerWaalsContact OD1-N 3.14Å; D430-R432 WeakPolarHBondContact OD2-CD 3.04Å; D430-R432 WeakPolarHBondContact OD2-CG 3.37Å; D430-R432 IonicContact OD2-CZ 3.81Å; D430-R432 IonicContact OD2-NE 2.77Å; D430-R432 IonicContact OD2-NH1 3.54Å; D430-R432 PolarHBondContact OD2-NH1 2.04Å; D430-Y434 PolarHBondContact OD2-OH 3.4Å
431Q90.9Very high95.6Very high177 Ų17735.9 Ų35.983%0.82719%0.186SC*.SBendtrans63.16.6-177.6-52.6178.97.800114.7G428 L429G428-Q431 WeakPolarHBondContact O-CA 3.43Å; G428-Q431 PolarHBondContact O-N 3.32Å; L429-Q431 PolarHBondContact O-N 3.25Å
432R92.6Very high95.5Very high135 Ų13537 Ų3751%0.50920%0.197SC..  trans-82.9142.7175.5-60-172.9-174.9128.7-12.5110.6S427 G428 D430 Y434S427-R432 WeakPolarHBondContact CA-O 3.3Å; G428-R432 PolarHBondContact N-O 3.21Å; D430-R432 PolarHBondContact O-N 3.03Å; D430-R432 VanDerWaalsContact O-N 3.13Å; D430-R432 WeakPolarHBondContact OD1-CB 3.28Å; D430-R432 PolarHBondContact OD1-N 2.93Å; D430-R432 VanDerWaalsContact OD1-N 3.14Å; D430-R432 WeakPolarHBondContact OD2-CD 3.04Å; D430-R432 WeakPolarHBondContact OD2-CG 3.37Å; D430-R432 IonicContact OD2-CZ 3.81Å; D430-R432 IonicContact OD2-NE 2.77Å; D430-R432 IonicContact OD2-NH1 3.54Å; D430-R432 PolarHBondContact OD2-NH1 2.04Å; R432-Y434 HydrophobicContact CB-CD2 4.43Å; R432-Y434 HydrophobicContact CB-CE2 3.69Å; R432-Y434 VanDerWaalsContact O-CD2 3.31Å; R432-Y434 WeakPolarHBondContact O-CD2 3.49Å; R432-Y434 WeakPolarHBondContact O-CE2 3.46Å
433A93.3Very high95.5Very high65 Ų6540.8 Ų40.854%0.53721%0.214SC..EExtended strand (participates in β ladder)trans-83.9127.8172.500000110.5R425R425-A433 HydrophobicContact CG-CB 4.17Å
434Y95.3Very high95.5Very high16 Ų1640.8 Ų40.86%0.06322%0.215CC..EExtended strand (participates in β ladder)trans-116.6148.2173.9-62.2-94.8000109.8R425 V426 D430 R432 L450 L452 L542 M543R425-Y434 WeakPolarHBondContact CA-O 3.26Å; V426-Y434 PolarHBondContact N-O 2.68Å; V426-Y434 PolarHBondContact O-N 3.47Å; D430-Y434 PolarHBondContact OD2-OH 3.4Å; R432-Y434 HydrophobicContact CB-CD2 4.43Å; R432-Y434 HydrophobicContact CB-CE2 3.69Å; R432-Y434 VanDerWaalsContact O-CD2 3.31Å; R432-Y434 WeakPolarHBondContact O-CD2 3.49Å; R432-Y434 WeakPolarHBondContact O-CE2 3.46Å; Y434-L450 HydrophobicContact CD1-CD1 4.41Å; Y434-L450 HydrophobicContact CG-CD1 4.32Å; Y434-L452 HydrophobicContact CD1-CD2 4.39Å; Y434-L452 HydrophobicContact CE1-CD2 4.1Å; Y434-L542 HydrophobicContact CD2-CD1 3.7Å; Y434-L542 HydrophobicContact CE1-CB 4.4Å; Y434-L542 HydrophobicContact CE1-CD1 4.43Å; Y434-L542 HydrophobicContact CE2-CD1 3.46Å; Y434-L542 VanDerWaalsContact CE2-CD1 3.46Å; Y434-L542 HydrophobicContact CG-CD1 4.31Å; Y434-M543 HydrophobicContact CE1-SD 4.19Å
435N96.5Very high95.5Very high29 Ų2943.7 Ų43.716%0.15523%0.225CC..EExtended strand (participates in β ladder)trans-99127.1173.6-64.8-13.8000108.9Y315 V423 D424 R425 I451Y315-N435 PolarHBondContact OH-ND2 3.07Å; V423-N435 HydrophobicContact CG1-CB 4.22Å; D424-N435 WeakPolarHBondContact O-CA 3.45Å; R425-N435 PolarHBondContact NE-OD1 3.33Å; N435-I451 PolarHBondContact O-N 3.07Å; N435-I451 VanDerWaalsContact O-N 3.08Å
436M97.3Very high95.6Very high0 Ų039.8 Ų39.80%021%0.211CC..EExtended strand (participates in β ladder)trans-115.2116.5-176-179.468.3-178.300109.7V423 D424 V426 F438 R448 L450 I459 P514 Y515V423-M436 VanDerWaalsContact CA-O 3.31Å; V423-M436 WeakPolarHBondContact CA-O 3.42Å; D424-M436 PolarHBondContact N-O 2.62Å; D424-M436 PolarHBondContact O-N 3.28Å; V426-M436 HydrophobicContact CG1-CB 4.11Å; M436-F438 HydrophobicContact CB-CE2 4.37Å; M436-F438 HydrophobicContact CE-CE1 4.46Å; M436-F438 HydrophobicContact CE-CZ 4.42Å; M436-F438 HydrophobicContact CG-CD2 4.48Å; M436-F438 HydrophobicContact CG-CE2 3.74Å; M436-F438 HydrophobicContact CG-CZ 3.85Å; M436-R448 HydrophobicContact CE-CB 3.58Å; M436-R448 HydrophobicContact CE-CG 4.22Å; M436-L450 HydrophobicContact SD-CB 4.26Å; M436-L450 HydrophobicContact SD-CD1 4.3Å; M436-I459 HydrophobicContact CE-CD1 3.85Å; M436-I459 HydrophobicContact SD-CD1 4.03Å; M436-P514 HydrophobicContact SD-CG 4.26Å; M436-Y515 HydrophobicContact CG-CE2 3.89Å
437L98.3Very high95.8Very high0 Ų039.3 Ų39.30%021%0.208CC..EExtended strand (participates in β ladder)trans-94.2138.9-178.4-75.560.2000110.5Y315 V330 L421 V423 I439 V449 I451Y315-L437 HydrophobicContact CE1-CD1 4.45Å; V330-L437 HydrophobicContact CG1-CD2 3.9Å; L421-L437 HydrophobicContact CD1-CB 4.09Å; L421-L437 HydrophobicContact CD1-CD2 4.24Å; L421-L437 HydrophobicContact CD1-CG 4.03Å; V423-L437 HydrophobicContact CG1-CD1 4.11Å; V423-L437 HydrophobicContact CG2-CD1 4.37Å; V423-L437 HydrophobicContact CG2-CG 4.09Å; L437-I439 HydrophobicContact CB-CD1 4.33Å; L437-I439 HydrophobicContact CB-CG1 4.18Å; L437-I439 HydrophobicContact CD2-CD1 4.38Å; L437-V449 HydrophobicContact CB-CB 4.26Å; L437-V449 PolarHBondContact N-O 3.38Å; L437-V449 PolarHBondContact O-N 2.99Å; L437-I451 HydrophobicContact CD1-CD1 3.99Å; L437-I451 HydrophobicContact CD1-CG1 3.53Å; L437-I451 HydrophobicContact CD2-CD1 4.26Å
438F98.6Very high96Very high1 Ų135.6 Ų35.60%0.00418%0.181CC..EExtended strand (participates in β ladder)trans-119.5113.2173-63.2-89.5000107.6L421 A422 D424 M436 L446 R448 L474 I476 L483 L496 Y515L421-F438 WeakPolarHBondContact CA-O 3.06Å; A422-F438 HydrophobicContact CB-CB 4.36Å; A422-F438 PolarHBondContact N-O 3.13Å; A422-F438 PolarHBondContact O-N 3.38Å; D424-F438 HydrophobicContact CB-CE2 4.31Å; M436-F438 HydrophobicContact CB-CE2 4.37Å; M436-F438 HydrophobicContact CE-CE1 4.46Å; M436-F438 HydrophobicContact CE-CZ 4.42Å; M436-F438 HydrophobicContact CG-CD2 4.48Å; M436-F438 HydrophobicContact CG-CE2 3.74Å; M436-F438 HydrophobicContact CG-CZ 3.85Å; F438-L446 HydrophobicContact CB-CD1 4.22Å; F438-R448 HydrophobicContact CD1-CG 4Å; F438-R448 HydrophobicContact CE1-CG 4.06Å; F438-L474 WeakPolarHBondContact O-CD2 3.42Å; F438-I476 HydrophobicContact CD2-CD1 4.39Å; F438-I476 HydrophobicContact CE2-CD1 4.16Å; F438-L483 HydrophobicContact CB-CD1 4.21Å; F438-L483 HydrophobicContact CB-CD2 3.94Å; F438-L483 HydrophobicContact CD1-CD2 3.75Å; F438-L483 HydrophobicContact CG-CD1 4.36Å; F438-L483 HydrophobicContact CG-CD2 4.04Å; F438-L496 HydrophobicContact CE1-CB 4.45Å; F438-L496 HydrophobicContact CE1-CD2 4.12Å; F438-L496 HydrophobicContact CE2-CD2 4.2Å; F438-L496 HydrophobicContact CZ-CB 3.97Å; F438-L496 HydrophobicContact CZ-CD1 4.39Å; F438-L496 HydrophobicContact CZ-CD2 3.78Å; F438-L496 HydrophobicContact CZ-CG 4.23Å; F438-Y515 HydrophobicContact CZ-CE2 4.04Å
439I98.6Very high96.3Very high0 Ų035.3 Ų35.30%018%0.178CC..EExtended strand (participates in β ladder)trans-121.3114.8-166.5-52.3177.5000110.1I317 V330 L411 F418 L421 L437 L446 Q447 V449I317-I439 HydrophobicContact CD1-CG2 4.25Å; V330-I439 HydrophobicContact CG2-CD1 4.08Å; L411-I439 HydrophobicContact CD2-CD1 3.41Å; L411-I439 VanDerWaalsContact CD2-CD1 3.41Å; F418-I439 HydrophobicContact CB-CG2 3.81Å; F418-I439 HydrophobicContact CD1-CG2 3.56Å; F418-I439 HydrophobicContact CD2-CG2 3.81Å; F418-I439 HydrophobicContact CE1-CG2 3.96Å; F418-I439 HydrophobicContact CE2-CD1 4.34Å; F418-I439 HydrophobicContact CE2-CG2 4.22Å; F418-I439 HydrophobicContact CG-CG2 3.47Å; F418-I439 VanDerWaalsContact CG-CG2 3.47Å; F418-I439 HydrophobicContact CZ-CG2 4.27Å; L421-I439 HydrophobicContact CD1-CG1 3.83Å; L437-I439 HydrophobicContact CB-CD1 4.33Å; L437-I439 HydrophobicContact CB-CG1 4.18Å; L437-I439 HydrophobicContact CD2-CD1 4.38Å; I439-L446 CarbonylContact O-C 3.38Å; I439-L446 WeakPolarHBondContact O-CA 3.49Å; I439-Q447 HydrophobicContact CB-CB 4.39Å; I439-Q447 PolarHBondContact N-O 2.85Å; I439-Q447 PolarHBondContact O-N 2.81Å; I439-V449 HydrophobicContact CD1-CG2 3.98Å
440G98.4Very high96.5Very high0 Ų032.4 Ų32.40%016%0.163CC..EExtended strand (participates in β ladder)trans-84147.7174.500000112.5F418 T419 K420 W445F418-G440 CarbonylContact C-O 3.55Å; F418-G440 WeakPolarHBondContact CA-O 3.24Å; T419-G440 PolarHBondContact N-O 2.68Å; T419-G440 PolarHBondContact OG1-O 3.48Å; K420-G440 PolarHBondContact O-N 2.88Å; G440-W445 CarbonylContact C-O 3.57Å; G440-W445 WeakPolarHBondContact CA-O 3.23Å
441T97.9Very high96.7Very high2 Ų230 Ų301%0.01215%0.149CC..EExtended strand (participates in β ladder)trans-114.4161.6178.1800000113.5V416 N417 F418 Q443 G444 W445 V471V416-T441 HydrophobicContact CG1-CG2 3.72Å; N417-T441 CarbonylContact O-C 3.43Å; N417-T441 WeakPolarHBondContact O-CA 3.04Å; F418-T441 HydrophobicContact CD1-CG2 4.14Å; F418-T441 HydrophobicContact CE1-CG2 4.49Å; T441-Q443 PolarHBondContact O-N 2.84Å; T441-Q443 PolarHBondContact OG1-N 3.11Å; T441-G444 PolarHBondContact O-N 2.89Å; T441-G444 PolarHBondContact OG1-N 2.79Å; T441-W445 HydrophobicContact CG2-CB 3.98Å; T441-W445 PolarHBondContact N-O 2.82Å; T441-W445 WeakPolarHBondContact OG1-CB 3.49Å; T441-W445 PolarHBondContact OG1-N 3.32Å; T441-V471 PolarHBondContact O-N 2.93Å
442A96.7Very high96.6Very high35 Ų3522.1 Ų22.129%0.28911%0.113SC..THydrogen-bonded Turntrans-67.2-16.6174.900000113.4N417 T419 Q469 P470N417-A442 HydrophobicContact CB-CB 4.11Å; N417-A442 PolarHBondContact O-N 3.03Å; T419-A442 HydrophobicContact CG2-CB 3.83Å; A442-Q469 CarbonylContact O-C 3.48Å; A442-P470 WeakPolarHBondContact O-CA 3.46Å
443Q96.6Very high96.2Very high78 Ų7819 Ų1936%0.36412%0.122SC..THydrogen-bonded Turntrans-99.80-179.2-66.278.114.100113.4T441 Q469T441-Q443 PolarHBondContact O-N 2.84Å; T441-Q443 PolarHBondContact OG1-N 3.11Å; Q443-Q469 CarbonylContact C-O 3.56Å
444G97.3Very high95.5Very high1 Ų119.6 Ų19.61%0.0112%0.123CC..SBendtrans92.730.5174.500000115T441 L464 Q469T441-G444 PolarHBondContact O-N 2.89Å; T441-G444 PolarHBondContact OG1-N 2.79Å; G444-L464 VanDerWaalsContact O-CB 3.29Å; G444-L464 WeakPolarHBondContact O-CB 3.33Å; G444-L464 PolarHBondContact O-N 2.91Å; G444-Q469 WeakPolarHBondContact CA-O 3.13Å; G444-Q469 PolarHBondContact N-O 3.46Å
445W97.8Very high94.9Very high65 Ų6523.2 Ų23.225%0.24614%0.141CC..EExtended strand (participates in β ladder)trans-111.5154.1176.7-61.671.9000111T30 G440 T441 E461 I462 Q463T30-W445 HydrophobicContact CG2-CH2 4.24Å; T30-W445 HydrophobicContact CG2-CZ3 3.88Å; G440-W445 CarbonylContact C-O 3.57Å; G440-W445 WeakPolarHBondContact CA-O 3.23Å; T441-W445 HydrophobicContact CG2-CB 3.98Å; T441-W445 PolarHBondContact N-O 2.82Å; T441-W445 WeakPolarHBondContact OG1-CB 3.49Å; T441-W445 PolarHBondContact OG1-N 3.32Å; W445-E461 HydrophobicContact CE3-CB 4.3Å; W445-E461 HydrophobicContact CE3-CG 4.02Å; W445-E461 HydrophobicContact CZ3-CG 4.07Å; W445-I462 CarbonylContact C-O 3.6Å; W445-I462 VanDerWaalsContact CA-O 3.31Å; W445-I462 WeakPolarHBondContact CA-O 3.49Å; W445-Q463 HydrophobicContact CD2-CB 4.17Å; W445-Q463 HydrophobicContact CD2-CG 4.49Å; W445-Q463 HydrophobicContact CE3-CB 3.92Å; W445-Q463 HydrophobicContact CH2-CB 3.71Å; W445-Q463 HydrophobicContact CH2-CG 4.19Å; W445-Q463 HydrophobicContact CZ2-CB 3.96Å; W445-Q463 HydrophobicContact CZ2-CG 3.94Å; W445-Q463 HydrophobicContact CZ3-CB 3.69Å
446L98.2Very high94.8Very high2 Ų222.4 Ų22.41%0.0114%0.137CC..EExtended strand (participates in β ladder)trans-116.8123167.5179.575.2000109.4F438 I439 R448 E461 I462 L464 L483 I485 L494F438-L446 HydrophobicContact CB-CD1 4.22Å; I439-L446 CarbonylContact O-C 3.38Å; I439-L446 WeakPolarHBondContact O-CA 3.49Å; L446-R448 HydrophobicContact CD2-CG 4.48Å; L446-E461 CarbonylContact O-C 3.49Å; L446-E461 WeakPolarHBondContact O-CA 3.42Å; L446-I462 PolarHBondContact N-O 2.76Å; L446-I462 PolarHBondContact O-N 3.18Å; L446-L464 HydrophobicContact CB-CD1 4.15Å; L446-L464 HydrophobicContact CB-CD2 3.9Å; L446-L464 HydrophobicContact CB-CG 4.16Å; L446-L483 HydrophobicContact CD1-CD2 3.91Å; L446-L483 HydrophobicContact CD2-CD2 3.58Å; L446-L483 HydrophobicContact CG-CD2 4.42Å; L446-I485 HydrophobicContact CD2-CD1 4.23Å; L446-L494 HydrophobicContact CD2-CD2 3.83Å
447Q97.8Very high94.6Very high6 Ų623.2 Ų23.23%0.02814%0.141CC..EExtended strand (participates in β ladder)trans-96.5133.8167.8-67.3-170.9-18.700110.8I439 V449 V458 E461I439-Q447 HydrophobicContact CB-CB 4.39Å; I439-Q447 PolarHBondContact N-O 2.85Å; I439-Q447 PolarHBondContact O-N 2.81Å; Q447-V449 HydrophobicContact CB-CG2 4.1Å; Q447-V458 HydrophobicContact CB-CG1 4.38Å; Q447-E461 HydrophobicContact CG-CB 3.99Å
448R97.8Very high94.6Very high4 Ų423.3 Ų23.32%0.01514%0.142CC..EExtended strand (participates in β ladder)trans-105.6113175.7-75.5-176.972.5-115.9-9.7108.6M436 F438 L446 I459 E460 L496 D513M436-R448 HydrophobicContact CE-CB 3.58Å; M436-R448 HydrophobicContact CE-CG 4.22Å; F438-R448 HydrophobicContact CD1-CG 4Å; F438-R448 HydrophobicContact CE1-CG 4.06Å; L446-R448 HydrophobicContact CD2-CG 4.48Å; R448-I459 PolarHBondContact O-N 2.78Å; R448-E460 HydrophobicContact CB-CG 4.08Å; R448-E460 VanDerWaalsContact CD-OE1 3.29Å; R448-E460 WeakPolarHBondContact CD-OE1 3.36Å; R448-E460 HydrophobicContact CG-CG 4.36Å; R448-E460 IonicContact CZ-OE1 2.7Å; R448-E460 PolarHBondContact N-O 3.38Å; R448-E460 IonicContact NE-OE1 3.54Å; R448-E460 IonicContact NH1-OE1 2.85Å; R448-E460 PolarHBondContact NH1-OE1 3.04Å; R448-L496 PolarHBondContact NE-O 3.16Å; R448-L496 PolarHBondContact NH2-O 3.41Å; R448-D513 IonicContact CZ-OD2 3.89Å; R448-D513 IonicContact NH1-OD2 3.33Å; R448-D513 PolarHBondContact NH1-OD2 3.17Å; R448-D513 IonicContact NH2-OD1 2.68Å; R448-D513 PolarHBondContact NH2-OD1 2.68Å; R448-D513 IonicContact NH2-OD2 3.73Å; R448-D513 PolarHBondContact NH2-OD2 2.71Å
449V97.9Very high94.5Very high0 Ų023.3 Ų23.30%014%0.142CC..EExtended strand (participates in β ladder)trans-131121.2-166.3-167.70000112L411 L437 I439 Q447 A456 H457 V458L411-V449 HydrophobicContact CD2-CG1 4.42Å; L411-V449 HydrophobicContact CD2-CG2 4.16Å; L437-V449 HydrophobicContact CB-CB 4.26Å; L437-V449 PolarHBondContact N-O 3.38Å; L437-V449 PolarHBondContact O-N 2.99Å; I439-V449 HydrophobicContact CD1-CG2 3.98Å; Q447-V449 HydrophobicContact CB-CG2 4.1Å; V449-A456 HydrophobicContact CG1-CB 3.9Å; V449-H457 CarbonylContact C-O 3.53Å; V449-H457 WeakPolarHBondContact CA-O 3.44Å; V449-V458 HydrophobicContact CG1-CG2 4.08Å; V449-V458 HydrophobicContact CG2-CB 4.41Å; V449-V458 HydrophobicContact CG2-CG1 4.17Å; V449-V458 HydrophobicContact CG2-CG2 3.99Å
450L97.3Very high94.4Very high0 Ų023.4 Ų23.40%014%0.142CC..EExtended strand (participates in β ladder)trans-91.7133.5175.9-173.965.2000111.1Y434 M436 L452 A456 H457 I459 R512 P514 L542Y434-L450 HydrophobicContact CD1-CD1 4.41Å; Y434-L450 HydrophobicContact CG-CD1 4.32Å; M436-L450 HydrophobicContact SD-CB 4.26Å; M436-L450 HydrophobicContact SD-CD1 4.3Å; L450-L452 HydrophobicContact CD2-CD1 4.21Å; L450-L452 HydrophobicContact CD2-CD2 3.82Å; L450-L452 HydrophobicContact CD2-CG 4.01Å; L450-L452 HydrophobicContact CG-CD1 4.4Å; L450-L452 HydrophobicContact CG-CD2 4.36Å; L450-L452 HydrophobicContact CG-CG 4.08Å; L450-A456 WeakPolarHBondContact O-CA 3.37Å; L450-H457 PolarHBondContact N-O 2.86Å; L450-H457 PolarHBondContact O-N 3.48Å; L450-I459 HydrophobicContact CB-CD1 3.91Å; L450-R512 VanDerWaalsContact CD2-O 3.26Å; L450-R512 WeakPolarHBondContact CD2-O 3.28Å; L450-P514 HydrophobicContact CD1-CB 4.31Å; L450-P514 HydrophobicContact CD1-CG 3.88Å; L450-L542 HydrophobicContact CD2-CD2 4.47Å
451I95.2Very high94.3Very high13 Ų1325.3 Ų25.37%0.06715%0.151CC..EExtended strand (participates in β ladder)trans-92.7125.9171.4-51.9-54.6000110.4L410 N435 L437 A456L410-I451 HydrophobicContact CB-CD1 4.15Å; L410-I451 HydrophobicContact CD1-CD1 4.07Å; L410-I451 HydrophobicContact CD1-CG1 4.31Å; L410-I451 HydrophobicContact CD1-CG2 4.49Å; N435-I451 PolarHBondContact O-N 3.07Å; N435-I451 VanDerWaalsContact O-N 3.08Å; L437-I451 HydrophobicContact CD1-CD1 3.99Å; L437-I451 HydrophobicContact CD1-CG1 3.53Å; L437-I451 HydrophobicContact CD2-CD1 4.26Å; I451-A456 HydrophobicContact CD1-CB 3.93Å
452L90.1Very high94.3Very high13 Ų1325.5 Ų25.57%0.06815%0.152CC..EExtended strand (participates in β ladder)trans-123.871.2-172.5-68.9147.7000108.5Y434 L450 S454 E455 H457 R512 L542 M543Y434-L452 HydrophobicContact CD1-CD2 4.39Å; Y434-L452 HydrophobicContact CE1-CD2 4.1Å; L450-L452 HydrophobicContact CD2-CD1 4.21Å; L450-L452 HydrophobicContact CD2-CD2 3.82Å; L450-L452 HydrophobicContact CD2-CG 4.01Å; L450-L452 HydrophobicContact CG-CD1 4.4Å; L450-L452 HydrophobicContact CG-CD2 4.36Å; L450-L452 HydrophobicContact CG-CG 4.08Å; L452-S454 PolarHBondContact O-N 2.84Å; L452-S454 VanDerWaalsContact O-N 3.09Å; L452-E455 HydrophobicContact CB-CB 4.28Å; L452-E455 PolarHBondContact N-O 2.81Å; L452-E455 PolarHBondContact O-N 3.42Å; L452-H457 HydrophobicContact CD1-CB 3.47Å; L452-H457 VanDerWaalsContact CD1-CB 3.47Å; L452-R512 VanDerWaalsContact CD1-CZ 3.48Å; L452-L542 WeakPolarHBondContact CD2-O 3.39Å; L452-M543 HydrophobicContact CD2-SD 3.63Å
453G84.3Confident94.3Very high68 Ų6825.7 Ų25.770%0.70115%0.147SC*.THydrogen-bonded Turntrans69.4-102.6-170.100000111.1
454S77.4Confident94.4Very high78 Ų7822 Ų2255%0.54513%0.13SC..THydrogen-bonded Turntrans-103.2-6.1176.152.90000114.3L452L452-S454 PolarHBondContact O-N 2.84Å; L452-S454 VanDerWaalsContact O-N 3.09Å
455E83.8Confident94.3Very high93 Ų9322 Ų2244%0.43513%0.13SC..EExtended strand (participates in β ladder)trans-92.5142.9175.1-174.2-171.6134.700110.6L452 R512L452-E455 HydrophobicContact CB-CB 4.28Å; L452-E455 PolarHBondContact N-O 2.81Å; L452-E455 PolarHBondContact O-N 3.42Å; E455-R512 IonicContact OE1-NH1 3.73Å; E455-R512 PolarHBondContact OE1-NH1 2.89Å
456A92.6Very high94Very high11 Ų1124.1 Ų24.19%0.09115%0.146CC..EExtended strand (participates in β ladder)trans-111.3119.9166.800000110.1L410 L411 V449 L450 I451L410-A456 WeakPolarHBondContact O-CB 3.21Å; L411-A456 HydrophobicContact CB-CB 4.3Å; L411-A456 HydrophobicContact CD1-CB 4.42Å; V449-A456 HydrophobicContact CG1-CB 3.9Å; L450-A456 WeakPolarHBondContact O-CA 3.37Å; I451-A456 HydrophobicContact CD1-CB 3.93Å
457H94.9Very high93.8Very high18 Ų1828.1 Ų28.18%0.08317%0.174CC..EExtended strand (participates in β ladder)trans-102.6114.3176.3178.365.9000110.1V449 L450 L452 I459V449-H457 CarbonylContact C-O 3.53Å; V449-H457 WeakPolarHBondContact CA-O 3.44Å; L450-H457 PolarHBondContact N-O 2.86Å; L450-H457 PolarHBondContact O-N 3.48Å; L452-H457 HydrophobicContact CD1-CB 3.47Å; L452-H457 VanDerWaalsContact CD1-CB 3.47Å; H457-I459 PolarHBondContact O-N 3.07Å
458V96.8Very high93.7Very high2 Ų232 Ų321%0.01221%0.207CC..EExtended strand (participates in β ladder)trans-82.4102.7176-172.40000108.7P25 P27 R28 L411 Q447 V449P25-V458 HydrophobicContact CB-CG2 4.35Å; P25-V458 HydrophobicContact CG-CG2 3.97Å; P27-V458 HydrophobicContact CB-CB 4.44Å; P27-V458 HydrophobicContact CB-CG1 3.71Å; P27-V458 HydrophobicContact CG-CG1 3.84Å; R28-V458 PolarHBondContact N-O 3.11Å; L411-V458 HydrophobicContact CD1-CG2 4.11Å; Q447-V458 HydrophobicContact CB-CG1 4.38Å; V449-V458 HydrophobicContact CG1-CG2 4.08Å; V449-V458 HydrophobicContact CG2-CB 4.41Å; V449-V458 HydrophobicContact CG2-CG1 4.17Å; V449-V458 HydrophobicContact CG2-CG2 3.99Å
459I97.1Very high93.7Very high1 Ų133.2 Ų33.21%0.00521%0.212CC..EExtended strand (participates in β ladder)trans-68.7-48.5-175.3-66.6163000110.2R28 K29 M436 R448 L450 H457 Y502 D513R28-I459 WeakPolarHBondContact CB-O 3.42Å; K29-I459 PolarHBondContact N-O 2.78Å; M436-I459 HydrophobicContact CE-CD1 3.85Å; M436-I459 HydrophobicContact SD-CD1 4.03Å; R448-I459 PolarHBondContact O-N 2.78Å; L450-I459 HydrophobicContact CB-CD1 3.91Å; H457-I459 PolarHBondContact O-N 3.07Å; I459-Y502 WeakPolarHBondContact CG2-OH 3.2Å; I459-D513 HydrophobicContact CD1-CB 4.32Å; I459-D513 HydrophobicContact CG2-CB 4.32Å
460E96Very high93.6Very high1 Ų135.5 Ų35.51%0.00523%0.228CC..EExtended strand (participates in β ladder)trans-155.8156.9174.661-175.2169.700112.1K29 R448 I462 R501K29-E460 HydrophobicContact CB-CB 4.31Å; K29-E460 CarbonylContact O-C 3.59Å; K29-E460 WeakPolarHBondContact O-CA 3.36Å; K29-E460 WeakPolarHBondContact O-CB 3.43Å; R448-E460 HydrophobicContact CB-CG 4.08Å; R448-E460 VanDerWaalsContact CD-OE1 3.29Å; R448-E460 WeakPolarHBondContact CD-OE1 3.36Å; R448-E460 HydrophobicContact CG-CG 4.36Å; R448-E460 IonicContact CZ-OE1 2.7Å; R448-E460 PolarHBondContact N-O 3.38Å; R448-E460 IonicContact NE-OE1 3.54Å; R448-E460 IonicContact NH1-OE1 2.85Å; R448-E460 PolarHBondContact NH1-OE1 3.04Å; E460-I462 HydrophobicContact CG-CD1 4.38Å; E460-I462 HydrophobicContact CG-CG1 4.19Å; E460-R501 IonicContact OE1-NH1 2.68Å; E460-R501 PolarHBondContact OE1-NH1 3.33Å; E460-R501 VanDerWaalsContact OE1-NH1 3.12Å; E460-R501 IonicContact OE2-CZ 3.58Å; E460-R501 IonicContact OE2-NH1 3.38Å; E460-R501 PolarHBondContact OE2-NH1 2.85Å
461E96.9Very high93.7Very high40 Ų4035.6 Ų35.619%0.18723%0.228CC..EExtended strand (participates in β ladder)trans-111.5141.2160.770.4-17116100109.5P27 K29 T30 V31 W445 L446 Q447P27-E461 HydrophobicContact CB-CB 4.03Å; P27-E461 HydrophobicContact CB-CG 3.94Å; P27-E461 HydrophobicContact CG-CB 4.07Å; P27-E461 HydrophobicContact CG-CG 4.05Å; K29-E461 PolarHBondContact O-N 3.43Å; T30-E461 WeakPolarHBondContact CB-OE1 3.46Å; T30-E461 HydrophobicContact CG2-CG 3.87Å; T30-E461 VanDerWaalsContact CG2-OE1 3.29Å; T30-E461 WeakPolarHBondContact CG2-OE1 3.38Å; T30-E461 PolarHBondContact OG1-OE1 2.79Å; V31-E461 PolarHBondContact N-O 2.86Å; W445-E461 HydrophobicContact CE3-CB 4.3Å; W445-E461 HydrophobicContact CE3-CG 4.02Å; W445-E461 HydrophobicContact CZ3-CG 4.07Å; L446-E461 CarbonylContact O-C 3.49Å; L446-E461 WeakPolarHBondContact O-CA 3.42Å; Q447-E461 HydrophobicContact CG-CB 3.99Å
462I97.6Very high93.8Very high6 Ų637.1 Ų37.13%0.03124%0.236CC..EExtended strand (participates in β ladder)trans-126124.3-176.2-51.9175.2000108.7V31 M40 W445 L446 E460 L464 L494V31-I462 HydrophobicContact CB-CG1 4.34Å; V31-I462 HydrophobicContact CB-CG2 4.39Å; V31-I462 HydrophobicContact CG1-CG2 4.38Å; M40-I462 HydrophobicContact SD-CG2 4.43Å; W445-I462 CarbonylContact C-O 3.6Å; W445-I462 VanDerWaalsContact CA-O 3.31Å; W445-I462 WeakPolarHBondContact CA-O 3.49Å; L446-I462 PolarHBondContact N-O 2.76Å; L446-I462 PolarHBondContact O-N 3.18Å; E460-I462 HydrophobicContact CG-CD1 4.38Å; E460-I462 HydrophobicContact CG-CG1 4.19Å; I462-L464 HydrophobicContact CG2-CD2 4.48Å; I462-L464 PolarHBondContact O-N 2.93Å; I462-L494 HydrophobicContact CD1-CD2 4.5Å
463Q97.6Very high94.1Very high39 Ų3936.9 Ų36.918%0.18224%0.236CC..EExtended strand (participates in β ladder)trans-74.8115.9169.6-170.6-174.4-5.200109.3V31 W445 F465V31-Q463 PolarHBondContact O-N 3.27Å; W445-Q463 HydrophobicContact CD2-CB 4.17Å; W445-Q463 HydrophobicContact CD2-CG 4.49Å; W445-Q463 HydrophobicContact CE3-CB 3.92Å; W445-Q463 HydrophobicContact CH2-CB 3.71Å; W445-Q463 HydrophobicContact CH2-CG 4.19Å; W445-Q463 HydrophobicContact CZ2-CB 3.96Å; W445-Q463 HydrophobicContact CZ2-CG 3.94Å; W445-Q463 HydrophobicContact CZ3-CB 3.69Å; Q463-F465 WeakPolarHBondContact CG-O 3.42Å; Q463-F465 PolarHBondContact NE2-O 2.87Å
464L97.3Very high94.7Very high0 Ų034.7 Ų34.70%021%0.208CC..  trans-83.5-35.2-174.3-61.7178.6000112.7M40 R42 G444 L446 I462 V471 I485 L492 L494M40-L464 HydrophobicContact SD-CD2 4.14Å; R42-L464 PolarHBondContact NH1-O 2.94Å; R42-L464 PolarHBondContact NH2-O 3.3Å; G444-L464 VanDerWaalsContact O-CB 3.29Å; G444-L464 WeakPolarHBondContact O-CB 3.33Å; G444-L464 PolarHBondContact O-N 2.91Å; L446-L464 HydrophobicContact CB-CD1 4.15Å; L446-L464 HydrophobicContact CB-CD2 3.9Å; L446-L464 HydrophobicContact CB-CG 4.16Å; I462-L464 HydrophobicContact CG2-CD2 4.48Å; I462-L464 PolarHBondContact O-N 2.93Å; L464-V471 HydrophobicContact CD1-CG2 3.58Å; L464-I485 HydrophobicContact CD1-CD1 3.73Å; L464-I485 HydrophobicContact CD1-CG2 4.02Å; L464-I485 HydrophobicContact CD2-CD1 3.75Å; L464-I485 HydrophobicContact CG-CD1 4.41Å; L464-L492 HydrophobicContact CB-CD1 3.67Å; L464-L492 HydrophobicContact CD1-CD1 4.45Å; L464-L492 HydrophobicContact CD2-CD1 4.07Å; L464-L492 HydrophobicContact CG-CD1 4.29Å; L464-L494 HydrophobicContact CD2-CD1 4.37Å; L464-L494 HydrophobicContact CD2-CD2 3.75Å
465F95.3Very high95.6Very high3 Ų332.5 Ų32.51%0.01319%0.191CC..  trans-128.8142.7-170.9-46.9-68.5000110.6Y33 Q463 S467 Q469 V471 S487 E490 L492Y33-F465 VanDerWaalsContact CD2-C 3.41Å; Q463-F465 WeakPolarHBondContact CG-O 3.42Å; Q463-F465 PolarHBondContact NE2-O 2.87Å; F465-S467 VanDerWaalsContact CB-O 3.28Å; F465-S467 WeakPolarHBondContact CB-O 3.46Å; F465-Q469 HydrophobicContact CB-CG 4.19Å; F465-Q469 HydrophobicContact CD1-CG 4.47Å; F465-Q469 HydrophobicContact CD2-CG 3.47Å; F465-Q469 VanDerWaalsContact CD2-CG 3.47Å; F465-Q469 HydrophobicContact CE2-CG 3.95Å; F465-Q469 HydrophobicContact CG-CG 3.79Å; F465-Q469 VanDerWaalsContact CG-NE2 3.25Å; F465-V471 HydrophobicContact CE2-CG2 4.45Å; F465-S487 WeakPolarHBondContact CE1-OG 3.47Å; F465-S487 VanDerWaalsContact CZ-CB 3.42Å; F465-E490 HydrophobicContact CD1-CG 4.28Å; F465-E490 WeakPolarHBondContact CD1-OE1 3.33Å; F465-E490 HydrophobicContact CE1-CG 3.79Å; F465-L492 HydrophobicContact CD1-CD1 4.23Å; F465-L492 HydrophobicContact CE1-CD1 3.54Å; F465-L492 HydrophobicContact CE1-CD2 4.14Å; F465-L492 HydrophobicContact CE1-CG 3.85Å; F465-L492 HydrophobicContact CZ-CD1 3.84Å; F465-L492 HydrophobicContact CZ-CG 4.32Å
466D92Very high96.2Very high108 Ų10828.7 Ų28.758%0.57817%0.174SC*.SBendtrans-65.1-52.5175.5-178.860.3000110.5Y33Y33-D466 HydrophobicContact CD1-CB 3.89Å; Y33-D466 HydrophobicContact CD2-CB 4.11Å; Y33-D466 HydrophobicContact CE1-CB 3.87Å; Y33-D466 HydrophobicContact CE2-CB 4.03Å; Y33-D466 HydrophobicContact CG-CB 4.03Å
467S94.3Very high96.4Very high87 Ų8728.1 Ų28.161%0.60817%0.169SC*.SBendtrans-83.4129.4168.4-65.30000111.5F465 Q469F465-S467 VanDerWaalsContact CB-O 3.28Å; F465-S467 WeakPolarHBondContact CB-O 3.46Å; S467-Q469 PolarHBondContact O-N 3.34Å
468A96Very high96.2Very high86 Ų8630.8 Ų30.871%0.71118%0.181SC*.  trans-63.5124.8179.700000112.3
469Q96.5Very high95.9Very high30 Ų3035 Ų3514%0.1421%0.211CC..  trans-155.1154.4178.963.5178-38.800110.1A442 Q443 G444 F465 S467 S487 S489A442-Q469 CarbonylContact O-C 3.48Å; Q443-Q469 CarbonylContact C-O 3.56Å; G444-Q469 WeakPolarHBondContact CA-O 3.13Å; G444-Q469 PolarHBondContact N-O 3.46Å; F465-Q469 HydrophobicContact CB-CG 4.19Å; F465-Q469 HydrophobicContact CD1-CG 4.47Å; F465-Q469 HydrophobicContact CD2-CG 3.47Å; F465-Q469 VanDerWaalsContact CD2-CG 3.47Å; F465-Q469 HydrophobicContact CE2-CG 3.95Å; F465-Q469 HydrophobicContact CG-CG 3.79Å; F465-Q469 VanDerWaalsContact CG-NE2 3.25Å; S467-Q469 PolarHBondContact O-N 3.34Å; Q469-S487 PolarHBondContact NE2-OG 3.12Å; Q469-S487 PolarHBondContact OE1-OG 3.38Å; Q469-S489 PolarHBondContact NE2-OG 2.9Å; Q469-S489 PolarHBondContact OE1-OG 2.78Å
470P97.4Very high95.7Very high49 Ų4937.6 Ų37.632%0.31822%0.222SC..  trans-66.6149.1-178.127.2-36000113.3A442 D472A442-P470 WeakPolarHBondContact O-CA 3.46Å; P470-D472 WeakPolarHBondContact CG-OD1 3.28Å; P470-D472 PolarHBondContact O-N 2.93Å
471V98.4Very high95.6Very high1 Ų139.6 Ų39.61%0.00623%0.231CC..  trans-74.4103.3156.4174.80000107.9T419 K420 T441 L464 F465 S473 I485T419-V471 WeakPolarHBondContact CB-O 3.46Å; T419-V471 PolarHBondContact OG1-O 3.08Å; K420-V471 HydrophobicContact CB-CG1 4.15Å; K420-V471 HydrophobicContact CG-CG1 4.22Å; K420-V471 WeakPolarHBondContact CG-O 3.44Å; T441-V471 PolarHBondContact O-N 2.93Å; L464-V471 HydrophobicContact CD1-CG2 3.58Å; F465-V471 HydrophobicContact CE2-CG2 4.45Å; V471-S473 WeakPolarHBondContact CG1-O 3.28Å; V471-I485 HydrophobicContact CB-CG2 4.36Å; V471-I485 HydrophobicContact CG1-CG2 3.54Å; V471-I485 HydrophobicContact CG2-CG2 4.02Å
472D96.6Very high95.5Very high46 Ų4641 Ų4125%0.24624%0.235CC..  trans-82.5-33-177.6-75.5-26.4000111.7K420 P470 G486 R488K420-D472 WeakPolarHBondContact CE-O 3.41Å; P470-D472 WeakPolarHBondContact CG-OD1 3.28Å; P470-D472 PolarHBondContact O-N 2.93Å; D472-G486 PolarHBondContact N-O 2.85Å; D472-R488 PolarHBondContact OD2-N 3.04Å
473S96.9Very high95.5Very high8 Ų840.9 Ų40.96%0.05623%0.234CC..EExtended strand (participates in β ladder)trans-144.6153.2179.267.90000112.2Y51 S52 L54 V471 G486Y51-S473 PolarHBondContact O-OG 3.29Å; Y51-S473 VanDerWaalsContact O-OG 3.13Å; S52-S473 WeakPolarHBondContact O-CB 3.43Å; L54-S473 WeakPolarHBondContact CD1-OG 3.41Å; L54-S473 WeakPolarHBondContact CG-OG 3.46Å; V471-S473 WeakPolarHBondContact CG1-O 3.28Å; S473-G486 PolarHBondContact N-O 3.16Å; S473-G486 PolarHBondContact O-N 3.41Å; S473-G486 WeakPolarHBondContact OG-CA 3.34Å; S473-G486 PolarHBondContact OG-N 3.05Å
474L97.4Very high95.6Very high21 Ų2139 Ų3911%0.1123%0.226CC..EExtended strand (participates in β ladder)trans-148.8131.5-177.6-166.662000109.4K420 A422 F438 L483 Y484 I485K420-L474 HydrophobicContact CB-CB 3.77Å; K420-L474 HydrophobicContact CB-CD2 4.21Å; K420-L474 HydrophobicContact CG-CB 4.49Å; A422-L474 HydrophobicContact CB-CD2 4.06Å; A422-L474 HydrophobicContact CB-CG 4.12Å; F438-L474 WeakPolarHBondContact O-CD2 3.42Å; L474-L483 HydrophobicContact CD1-CD1 3.77Å; L474-L483 HydrophobicContact CD1-CD2 3.96Å; L474-L483 HydrophobicContact CD1-CG 3.79Å; L474-L483 HydrophobicContact CG-CD1 4.07Å; L474-Y484 WeakPolarHBondContact CA-O 3.02Å; L474-I485 HydrophobicContact CD1-CB 4.26Å; L474-I485 HydrophobicContact CD1-CD1 4.26Å; L474-I485 HydrophobicContact CD1-CG1 3.73Å; L474-I485 HydrophobicContact CD1-CG2 4.09Å
475T96.6Very high95.6Very high33 Ų3339 Ų3920%0.20223%0.226CC..EExtended strand (participates in β ladder)trans-148137.1-178.6-67.70000109.9L56 Y484L56-T475 HydrophobicContact CD1-CG2 3.85Å; L56-T475 HydrophobicContact CG-CG2 4Å; T475-Y484 PolarHBondContact N-O 3.27Å; T475-Y484 PolarHBondContact O-N 3.38Å
476I96.6Very high95.8Very high12 Ų1238.9 Ų38.96%0.06223%0.225CC..EExtended strand (participates in β ladder)trans-110.3134.6-177179.3162.3000110.5L56 F302 A422 D424 F438 L483 L496L56-I476 WeakPolarHBondContact CD1-O 3.45Å; F302-I476 HydrophobicContact CE2-CG2 4.2Å; F302-I476 HydrophobicContact CZ-CG2 4.15Å; A422-I476 HydrophobicContact CB-CB 4.19Å; A422-I476 HydrophobicContact CB-CG2 4.03Å; D424-I476 HydrophobicContact CB-CD1 3.75Å; F438-I476 HydrophobicContact CD2-CD1 4.39Å; F438-I476 HydrophobicContact CE2-CD1 4.16Å; I476-L483 HydrophobicContact CB-CD1 4.12Å; I476-L496 HydrophobicContact CD1-CD1 3.82Å; I476-L496 HydrophobicContact CD1-CD2 3.92Å; I476-L496 HydrophobicContact CG1-CD1 4.37Å; I476-L496 HydrophobicContact CG1-CD2 4.17Å
477S95.6Very high96Very high0 Ų033.7 Ų33.70%020%0.198CC..EExtended strand (participates in β ladder)trans-95.2110.8163159.50000108.5E60 S479 K480 K481 Y482E60-S477 VanDerWaalsContact CD-OG 3.31Å; E60-S477 WeakPolarHBondContact OE1-CA 3.02Å; E60-S477 WeakPolarHBondContact OE2-CB 3.14Å; E60-S477 PolarHBondContact OE2-OG 3.18Å; S477-S479 VanDerWaalsContact C-N 3.31Å; S477-K480 WeakPolarHBondContact OG-CB 3.49Å; S477-K480 WeakPolarHBondContact OG-CG 3.39Å; S477-K480 PolarHBondContact OG-N 3.23Å; S477-K481 WeakPolarHBondContact O-CA 3.41Å; S477-K481 PolarHBondContact O-N 3.03Å; S477-Y482 PolarHBondContact N-O 3.2Å
478H91.4Very high96.1Very high73 Ų7336.5 Ų36.534%0.33820%0.195SC..THydrogen-bonded Turntrans-74.5-26.1179.6-64.7-87.9000111.5E60 V423 D424 K481E60-H478 PolarHBondContact OE1-N 2.77Å; V423-H478 PolarHBondContact O-CE1 2.86Å; D424-H478 IonicContact OD1-CE1 3.37Å; D424-H478 IonicContact OD1-CG 2.77Å; D424-H478 IonicContact OD1-ND1 3.77Å; D424-H478 PolarHBondContact OD1-ND1 2.99Å; H478-K481 WeakPolarHBondContact O-CD 3.37Å; H478-K481 WeakPolarHBondContact O-CE 3.37Å; H478-K481 PolarHBondContact O-NZ 2.75Å
479S91.4Very high96.2Very high91 Ų9134.4 Ų34.464%0.63618%0.175SC*.THydrogen-bonded Turntrans-86.9-40-177.385.50000113.7E60 S477E60-S479 WeakPolarHBondContact OE2-CB 3.1Å; E60-S479 PolarHBondContact OE2-N 3.27Å; E60-S479 PolarHBondContact OE2-OG 3.36Å; S477-S479 VanDerWaalsContact C-N 3.31Å
480K91.6Very high96.2Very high55 Ų5534.2 Ų34.224%0.23917%0.174CC..THydrogen-bonded Turntrans-89.2-10179-51177.1174.7-67.10113.1E60 P76 N77 S477 Y482E60-K480 WeakPolarHBondContact O-CE 3.44Å; P76-K480 HydrophobicContact CB-CD 3.87Å; N77-K480 PolarHBondContact OD1-NZ 2.92Å; S477-K480 WeakPolarHBondContact OG-CB 3.49Å; S477-K480 WeakPolarHBondContact OG-CG 3.39Å; S477-K480 PolarHBondContact OG-N 3.23Å; K480-Y482 HydrophobicContact CB-CD2 3.75Å; K480-Y482 HydrophobicContact CB-CE2 4.33Å; K480-Y482 VanDerWaalsContact O-CD2 3.31Å; K480-Y482 WeakPolarHBondContact O-CD2 3.08Å; K480-Y482 PolarHBondContact O-N 3.25Å
481K93.6Very high96.2Very high43 Ų4331.9 Ų31.919%0.18716%0.159CC..THydrogen-bonded Turntrans5649.3-178.3-60.2-63.7-178.7-160.40112.5D424 S477 H478 L496 R527D424-K481 IonicContact OD1-NZ 2.83Å; D424-K481 IonicContact OD2-NZ 3.55Å; D424-K481 PolarHBondContact OD2-NZ 2.85Å; S477-K481 WeakPolarHBondContact O-CA 3.41Å; S477-K481 PolarHBondContact O-N 3.03Å; H478-K481 WeakPolarHBondContact O-CD 3.37Å; H478-K481 WeakPolarHBondContact O-CE 3.37Å; H478-K481 PolarHBondContact O-NZ 2.75Å; K481-L496 HydrophobicContact CB-CD1 4.35Å; K481-L496 HydrophobicContact CB-CG 4.31Å; K481-L496 HydrophobicContact CD-CD1 3.69Å; K481-L496 PolarHBondContact O-N 3.48Å; K481-L496 VanDerWaalsContact O-N 3.09Å; K481-R527 VanDerWaalsContact CB-NH2 3.29Å
482Y95.9Very high96.2Very high71 Ų7131.9 Ų31.928%0.27816%0.159SC..EExtended strand (participates in β ladder)trans-122.5154169-70.8-74.9000112S477 K480 Q493 L494 P495S477-Y482 PolarHBondContact N-O 3.2Å; K480-Y482 HydrophobicContact CB-CD2 3.75Å; K480-Y482 HydrophobicContact CB-CE2 4.33Å; K480-Y482 VanDerWaalsContact O-CD2 3.31Å; K480-Y482 WeakPolarHBondContact O-CD2 3.08Å; K480-Y482 PolarHBondContact O-N 3.25Å; Y482-Q493 HydrophobicContact CD1-CG 3.6Å; Y482-Q493 HydrophobicContact CE1-CG 4.16Å; Y482-Q493 VanDerWaalsContact CE1-NE2 3.33Å; Y482-Q493 HydrophobicContact CG-CG 4.01Å; Y482-L494 CarbonylContact C-O 3.58Å; Y482-L494 VanDerWaalsContact CA-O 3.32Å; Y482-L494 WeakPolarHBondContact CA-O 3.5Å; Y482-P495 HydrophobicContact CE1-CB 4.41Å
483L97.7Very high96.3Very high2 Ų230 Ų301%0.0115%0.149CC..EExtended strand (participates in β ladder)trans-117.3125.5171.8-174.672.6000108.1A422 F438 L446 L474 I476 I485 L494 L496A422-L483 HydrophobicContact CB-CD1 4.04Å; F438-L483 HydrophobicContact CB-CD1 4.21Å; F438-L483 HydrophobicContact CB-CD2 3.94Å; F438-L483 HydrophobicContact CD1-CD2 3.75Å; F438-L483 HydrophobicContact CG-CD1 4.36Å; F438-L483 HydrophobicContact CG-CD2 4.04Å; L446-L483 HydrophobicContact CD1-CD2 3.91Å; L446-L483 HydrophobicContact CD2-CD2 3.58Å; L446-L483 HydrophobicContact CG-CD2 4.42Å; L474-L483 HydrophobicContact CD1-CD1 3.77Å; L474-L483 HydrophobicContact CD1-CD2 3.96Å; L474-L483 HydrophobicContact CD1-CG 3.79Å; L474-L483 HydrophobicContact CG-CD1 4.07Å; I476-L483 HydrophobicContact CB-CD1 4.12Å; L483-I485 HydrophobicContact CD2-CD1 4.21Å; L483-I485 HydrophobicContact CD2-CG1 4.43Å; L483-I485 HydrophobicContact CG-CG1 4.3Å; L483-L494 PolarHBondContact N-O 3.34Å; L483-L494 PolarHBondContact O-N 3.07Å; L483-L496 HydrophobicContact CB-CD2 3.82Å
484Y98.4Very high96.2Very high0 Ų029.9 Ų29.90%015%0.147CC..EExtended strand (participates in β ladder)trans-103.8133.2176.8-46.3-79.8000109.3L56 L63 P76 I79 L474 T475 L492 Q493L56-Y484 HydrophobicContact CD1-CD2 4.45Å; L56-Y484 HydrophobicContact CD1-CE2 4.1Å; L56-Y484 HydrophobicContact CD2-CD2 4.32Å; L56-Y484 HydrophobicContact CD2-CE2 3.82Å; L56-Y484 HydrophobicContact CG-CE2 4.4Å; L63-Y484 HydrophobicContact CD1-CD2 4.42Å; L63-Y484 HydrophobicContact CD1-CG 4.36Å; L63-Y484 HydrophobicContact CD2-CD1 3.62Å; L63-Y484 HydrophobicContact CD2-CE1 4.19Å; L63-Y484 HydrophobicContact CD2-CG 3.8Å; P76-Y484 HydrophobicContact CB-CE1 4.46Å; P76-Y484 WeakPolarHBondContact CB-OH 3.25Å; P76-Y484 PolarHBondContact O-OH 2.85Å; I79-Y484 HydrophobicContact CG2-CD1 3.9Å; I79-Y484 HydrophobicContact CG2-CE1 3.98Å; L474-Y484 WeakPolarHBondContact CA-O 3.02Å; T475-Y484 PolarHBondContact N-O 3.27Å; T475-Y484 PolarHBondContact O-N 3.38Å; Y484-L492 CarbonylContact C-O 3.28Å; Y484-L492 VanDerWaalsContact CA-O 3.29Å; Y484-L492 WeakPolarHBondContact CA-O 3.05Å; Y484-Q493 HydrophobicContact CD1-CB 4.08Å; Y484-Q493 HydrophobicContact CD1-CG 4.11Å; Y484-Q493 HydrophobicContact CE1-CB 4.28Å; Y484-Q493 HydrophobicContact CE1-CG 3.83Å
485I98.6Very high96.1Very high0 Ų030.6 Ų30.60%015%0.153CC..EExtended strand (participates in β ladder)trans-130.6125.1-172.3-39.8-174.1000108.5L446 L464 V471 L474 L483 V491 L492 L494L446-I485 HydrophobicContact CD2-CD1 4.23Å; L464-I485 HydrophobicContact CD1-CD1 3.73Å; L464-I485 HydrophobicContact CD1-CG2 4.02Å; L464-I485 HydrophobicContact CD2-CD1 3.75Å; L464-I485 HydrophobicContact CG-CD1 4.41Å; V471-I485 HydrophobicContact CB-CG2 4.36Å; V471-I485 HydrophobicContact CG1-CG2 3.54Å; V471-I485 HydrophobicContact CG2-CG2 4.02Å; L474-I485 HydrophobicContact CD1-CB 4.26Å; L474-I485 HydrophobicContact CD1-CD1 4.26Å; L474-I485 HydrophobicContact CD1-CG1 3.73Å; L474-I485 HydrophobicContact CD1-CG2 4.09Å; L483-I485 HydrophobicContact CD2-CD1 4.21Å; L483-I485 HydrophobicContact CD2-CG1 4.43Å; L483-I485 HydrophobicContact CG-CG1 4.3Å; I485-V491 CarbonylContact O-C 3.58Å; I485-V491 VanDerWaalsContact O-CA 3.3Å; I485-V491 WeakPolarHBondContact O-CA 3.38Å; I485-L492 HydrophobicContact CB-CB 4.23Å; I485-L492 PolarHBondContact N-O 2.92Å; I485-L492 PolarHBondContact O-N 3.31Å; I485-L494 HydrophobicContact CD1-CD1 3.76Å; I485-L494 HydrophobicContact CD1-CD2 4.08Å; I485-L494 HydrophobicContact CD1-CG 4.46Å; I485-L494 HydrophobicContact CG1-CD1 4.26Å
486G98.1Very high96Very high0 Ų029 Ų290%014%0.144CC..EExtended strand (participates in β ladder)trans-112144.6177.100000112.1Y51 D472 S473Y51-G486 WeakPolarHBondContact O-CA 3.44Å; D472-G486 PolarHBondContact N-O 2.85Å; S473-G486 PolarHBondContact N-O 3.16Å; S473-G486 PolarHBondContact O-N 3.41Å; S473-G486 WeakPolarHBondContact OG-CA 3.34Å; S473-G486 PolarHBondContact OG-N 3.05Å
487S97.9Very high96Very high0 Ų028.6 Ų28.60%014%0.141CC..  trans-137.9-167.3-179.273.90000111.7Y51 F465 Q469 S489 E490Y51-S487 PolarHBondContact N-O 3.36Å; F465-S487 WeakPolarHBondContact CE1-OG 3.47Å; F465-S487 VanDerWaalsContact CZ-CB 3.42Å; Q469-S487 PolarHBondContact NE2-OG 3.12Å; Q469-S487 PolarHBondContact OE1-OG 3.38Å; S487-S489 PolarHBondContact OG-N 3.19Å; S487-S489 PolarHBondContact OG-OG 3.46Å; S487-E490 PolarHBondContact N-O 2.86Å; S487-E490 PolarHBondContact OG-N 3.19Å; S487-E490 PolarHBondContact OG-O 3.03Å
488R96.2Very high95.9Very high145 Ų14530.3 Ų30.355%0.54715%0.151SC..SBendtrans-68.7-33.1173.9-173.8173.8179.4-163-2.3112.9F49 N50 D472F49-R488 CarbonylContact C-O 3.57Å; F49-R488 VanDerWaalsContact CA-O 3.3Å; F49-R488 WeakPolarHBondContact CA-O 3.28Å; F49-R488 WeakPolarHBondContact CB-O 2.99Å; N50-R488 PolarHBondContact N-O 2.84Å; D472-R488 PolarHBondContact OD2-N 3.04Å
489S96.6Very high96.1Very high42 Ų4227.1 Ų27.129%0.29414%0.136SC..SBendtrans-97.2-32.3-17662.20000115.4S44 Y51 Q469 S487S44-S489 WeakPolarHBondContact CB-O 3.25Å; Y51-S489 VanDerWaalsContact CE2-C 3.44Å; Y51-S489 WeakPolarHBondContact CE2-O 3.44Å; Q469-S489 PolarHBondContact NE2-OG 2.9Å; Q469-S489 PolarHBondContact OE1-OG 2.78Å; S487-S489 PolarHBondContact OG-N 3.19Å; S487-S489 PolarHBondContact OG-OG 3.46Å
490E96.9Very high96.1Very high27 Ų2726.8 Ų26.813%0.12613%0.134CC..  trans-161.7173.9-164.668.8-157.5107.700113.5R42 F43 F465 S487 L492R42-E490 WeakPolarHBondContact CD-OE2 3.46Å; R42-E490 IonicContact CZ-OE2 2.69Å; R42-E490 IonicContact NE-OE2 2.69Å; R42-E490 VanDerWaalsContact NH1-CD 3.34Å; R42-E490 IonicContact NH1-OE1 2.73Å; R42-E490 IonicContact NH1-OE2 2.71Å; R42-E490 PolarHBondContact NH1-OE2 2.84Å; F43-E490 CarbonylContact O-C 3.52Å; F43-E490 WeakPolarHBondContact O-CA 3.16Å; F43-E490 WeakPolarHBondContact O-CB 3.24Å; F465-E490 HydrophobicContact CD1-CG 4.28Å; F465-E490 WeakPolarHBondContact CD1-OE1 3.33Å; F465-E490 HydrophobicContact CE1-CG 3.79Å; S487-E490 PolarHBondContact N-O 2.86Å; S487-E490 PolarHBondContact OG-N 3.19Å; S487-E490 PolarHBondContact OG-O 3.03Å; E490-L492 HydrophobicContact CG-CD2 3.77Å; E490-L492 HydrophobicContact CG-CG 4.39Å; E490-L492 WeakPolarHBondContact OE2-CD2 3.27Å
491V98.3Very high96Very high0 Ų026.3 Ų26.30%013%0.131CC..EExtended strand (participates in β ladder)trans-109.7138.8161.7-1760000109R42 F43 Y51 L54 V65 I79 I485R42-V491 CarbonylContact C-O 3.57Å; R42-V491 WeakPolarHBondContact CA-O 3.17Å; F43-V491 HydrophobicContact CB-CB 4.45Å; F43-V491 PolarHBondContact N-O 2.03Å; F43-V491 PolarHBondContact O-N 3.38Å; Y51-V491 HydrophobicContact CD1-CG2 3.89Å; Y51-V491 HydrophobicContact CG-CG2 3.95Å; L54-V491 HydrophobicContact CD2-CG1 4.12Å; L54-V491 HydrophobicContact CD2-CG2 4.21Å; V65-V491 HydrophobicContact CG1-CG2 3.85Å; V65-V491 HydrophobicContact CG2-CG2 4.34Å; I79-V491 HydrophobicContact CD1-CB 4.25Å; I79-V491 HydrophobicContact CD1-CG1 3.95Å; I79-V491 VanDerWaalsContact CD1-O 3.3Å; I79-V491 WeakPolarHBondContact CD1-O 3.16Å; I485-V491 CarbonylContact O-C 3.58Å; I485-V491 VanDerWaalsContact O-CA 3.3Å; I485-V491 WeakPolarHBondContact O-CA 3.38Å
492L97.9Very high96Very high0 Ų024.4 Ų24.40%012%0.123CC..EExtended strand (participates in β ladder)trans-112.1150.3173.5-50.1-178.3000111A41 R42 I79 L464 F465 Y484 I485 E490 L494A41-L492 CarbonylContact O-C 3.58Å; A41-L492 WeakPolarHBondContact O-CA 3.41Å; R42-L492 HydrophobicContact CB-CD2 4.46Å; R42-L492 HydrophobicContact CG-CD2 3.79Å; R42-L492 VanDerWaalsContact NH1-CD2 3.28Å; I79-L492 VanDerWaalsContact CD1-C 3.48Å; L464-L492 HydrophobicContact CB-CD1 3.67Å; L464-L492 HydrophobicContact CD1-CD1 4.45Å; L464-L492 HydrophobicContact CD2-CD1 4.07Å; L464-L492 HydrophobicContact CG-CD1 4.29Å; F465-L492 HydrophobicContact CD1-CD1 4.23Å; F465-L492 HydrophobicContact CE1-CD1 3.54Å; F465-L492 HydrophobicContact CE1-CD2 4.14Å; F465-L492 HydrophobicContact CE1-CG 3.85Å; F465-L492 HydrophobicContact CZ-CD1 3.84Å; F465-L492 HydrophobicContact CZ-CG 4.32Å; Y484-L492 CarbonylContact C-O 3.28Å; Y484-L492 VanDerWaalsContact CA-O 3.29Å; Y484-L492 WeakPolarHBondContact CA-O 3.05Å; I485-L492 HydrophobicContact CB-CB 4.23Å; I485-L492 PolarHBondContact N-O 2.92Å; I485-L492 PolarHBondContact O-N 3.31Å; E490-L492 HydrophobicContact CG-CD2 3.77Å; E490-L492 HydrophobicContact CG-CG 4.39Å; E490-L492 WeakPolarHBondContact OE2-CD2 3.27Å; L492-L494 HydrophobicContact CB-CD1 3.64Å; L492-L494 HydrophobicContact CD1-CD1 4.25Å
493Q97.8Very high95.7Very high7 Ų725.7 Ų25.73%0.03313%0.131CC..EExtended strand (participates in β ladder)trans-123.8117.1168.6172.2-169.3-0.900108.8A41 P76 N77 I79 Y482 Y484A41-Q493 HydrophobicContact CB-CB 4.22Å; A41-Q493 PolarHBondContact N-O 2.82Å; A41-Q493 VanDerWaalsContact N-O 3.1Å; A41-Q493 PolarHBondContact O-N 2.88Å; P76-Q493 PolarHBondContact O-NE2 3.28Å; N77-Q493 PolarHBondContact O-NE2 2.93Å; I79-Q493 HydrophobicContact CB-CB 4.46Å; I79-Q493 HydrophobicContact CD1-CB 3.72Å; I79-Q493 HydrophobicContact CG1-CB 3.74Å; I79-Q493 HydrophobicContact CG2-CB 3.96Å; I79-Q493 HydrophobicContact CG2-CG 4.46Å; Y482-Q493 HydrophobicContact CD1-CG 3.6Å; Y482-Q493 HydrophobicContact CE1-CG 4.16Å; Y482-Q493 VanDerWaalsContact CE1-NE2 3.33Å; Y482-Q493 HydrophobicContact CG-CG 4.01Å; Y484-Q493 HydrophobicContact CD1-CB 4.08Å; Y484-Q493 HydrophobicContact CD1-CG 4.11Å; Y484-Q493 HydrophobicContact CE1-CB 4.28Å; Y484-Q493 HydrophobicContact CE1-CG 3.83Å
494L96.1Very high95.4Very high6 Ų626.3 Ų26.33%0.03114%0.136CC..EExtended strand (participates in β ladder)trans-115.5139179.3-78.371.2000110.2M40 L446 I462 L464 Y482 L483 I485 L492M40-L494 HydrophobicContact CB-CD1 4.26Å; M40-L494 HydrophobicContact CB-CG 4.45Å; M40-L494 HydrophobicContact CG-CD1 4.05Å; M40-L494 HydrophobicContact CG-CD2 4.41Å; M40-L494 HydrophobicContact CG-CG 3.83Å; M40-L494 HydrophobicContact SD-CD1 3.75Å; M40-L494 HydrophobicContact SD-CD2 3.79Å; M40-L494 HydrophobicContact SD-CG 3.75Å; L446-L494 HydrophobicContact CD2-CD2 3.83Å; I462-L494 HydrophobicContact CD1-CD2 4.5Å; L464-L494 HydrophobicContact CD2-CD1 4.37Å; L464-L494 HydrophobicContact CD2-CD2 3.75Å; Y482-L494 CarbonylContact C-O 3.58Å; Y482-L494 VanDerWaalsContact CA-O 3.32Å; Y482-L494 WeakPolarHBondContact CA-O 3.5Å; L483-L494 PolarHBondContact N-O 3.34Å; L483-L494 PolarHBondContact O-N 3.07Å; I485-L494 HydrophobicContact CD1-CD1 3.76Å; I485-L494 HydrophobicContact CD1-CD2 4.08Å; I485-L494 HydrophobicContact CD1-CG 4.46Å; I485-L494 HydrophobicContact CG1-CD1 4.26Å; L492-L494 HydrophobicContact CB-CD1 3.64Å; L492-L494 HydrophobicContact CD1-CD1 4.25Å
495P95Very high95Very high36 Ų3628.9 Ų28.923%0.23415%0.148CC..EExtended strand (participates in β ladder)trans-65.8148.2166.529.1-33.9000110.7S39 Y482 A497S39-P495 WeakPolarHBondContact O-CD 3.46Å; Y482-P495 HydrophobicContact CE1-CB 4.41Å; P495-A497 PolarHBondContact O-N 2.87Å; P495-A497 VanDerWaalsContact O-N 3.08Å
496L95.3Very high94.7Very high0 Ų029.1 Ų29.10%015%0.149CC..SBendtrans-62.9-17.6-180-64.5-165.9000114.5D424 F438 R448 I476 K481 L483 Y515D424-L496 HydrophobicContact CB-CD1 4.47Å; F438-L496 HydrophobicContact CE1-CB 4.45Å; F438-L496 HydrophobicContact CE1-CD2 4.12Å; F438-L496 HydrophobicContact CE2-CD2 4.2Å; F438-L496 HydrophobicContact CZ-CB 3.97Å; F438-L496 HydrophobicContact CZ-CD1 4.39Å; F438-L496 HydrophobicContact CZ-CD2 3.78Å; F438-L496 HydrophobicContact CZ-CG 4.23Å; R448-L496 PolarHBondContact NE-O 3.16Å; R448-L496 PolarHBondContact NH2-O 3.41Å; I476-L496 HydrophobicContact CD1-CD1 3.82Å; I476-L496 HydrophobicContact CD1-CD2 3.92Å; I476-L496 HydrophobicContact CG1-CD1 4.37Å; I476-L496 HydrophobicContact CG1-CD2 4.17Å; K481-L496 HydrophobicContact CB-CD1 4.35Å; K481-L496 HydrophobicContact CB-CG 4.31Å; K481-L496 HydrophobicContact CD-CD1 3.69Å; K481-L496 PolarHBondContact O-N 3.48Å; K481-L496 VanDerWaalsContact O-N 3.09Å; L483-L496 HydrophobicContact CB-CD2 3.82Å; L496-Y515 HydrophobicContact CB-CE1 4.2Å; L496-Y515 HydrophobicContact CB-CE2 4.09Å; L496-Y515 HydrophobicContact CD1-CE1 4.05Å
497A94.9Very high94.5Very high2 Ų229.6 Ų29.62%0.01715%0.152CC..  trans-153.3154.9170.400000111.7P495 Y515P495-A497 PolarHBondContact O-N 2.87Å; P495-A497 VanDerWaalsContact O-N 3.08Å; A497-Y515 HydrophobicContact CB-CD2 3.77Å; A497-Y515 HydrophobicContact CB-CG 4.01Å
498N94Very high94.4Very high37 Ų3729.8 Ų29.820%0.19815%0.153CC..  trans-129.276.9174.1-170.50.7000110.9S39 S500 R501S39-N498 WeakPolarHBondContact CB-ND2 3.35Å; N498-S500 VanDerWaalsContact C-N 3.25Å; N498-S500 PolarHBondContact O-N 3Å; N498-S500 PolarHBondContact OD1-OG 2.85Å; N498-R501 HydrophobicContact CB-CG 4.44Å; N498-R501 WeakPolarHBondContact O-CB 3.46Å; N498-R501 WeakPolarHBondContact O-CG 3.35Å; N498-R501 PolarHBondContact O-N 3.46Å
499C95.3Very high94.3Very high5 Ų523.2 Ų23.23%0.03413%0.129CC..G310 helixtrans-65.3-20.1-168.3-51.80000115R501 Y502 C516 C525 R527C499-R501 PolarHBondContact O-N 2.95Å; C499-R501 VanDerWaalsContact O-N 3.15Å; C499-Y502 WeakPolarHBondContact O-CD2 3.43Å; C499-Y502 PolarHBondContact O-N 3.05Å; C499-C516 WeakPolarHBondContact CA-SG 3.31Å; C499-C516 HydrophobicContact CB-CB 3.77Å; C499-C516 WeakPolarHBondContact CB-SG 3.35Å; C499-C516 WeakPolarHBondContact SG-CA 3.48Å; C499-C516 WeakPolarHBondContact SG-CB 3.46Å; C499-C516 CovalentContact SG-SG 2.03Å; C499-C516 PolarHBondContact SG-SG 2.83Å; C499-C525 WeakPolarHBondContact O-CB 3.46Å; C499-R527 WeakPolarHBondContact SG-CG 3.35Å
500S92.1Very high94.2Very high85 Ų8521.4 Ų21.459%0.59412%0.116SC*.G310 helixtrans-65.6-14.3176.759.70000113.4N498 Y502N498-S500 VanDerWaalsContact C-N 3.25Å; N498-S500 PolarHBondContact O-N 3Å; N498-S500 PolarHBondContact OD1-OG 2.85Å; S500-Y502 PolarHBondContact O-N 3.47Å
501R89.9Confident94.2Very high45 Ų4520.1 Ų20.117%0.1711%0.11CC..G310 helixtrans-64-7.9167.7-65.6-178.8178.4160.44.9113.9K29 S39 E460 N498 C499K29-R501 PolarHBondContact NZ-O 3.27Å; S39-R501 PolarHBondContact OG-NH2 3.25Å; S39-R501 VanDerWaalsContact OG-NH2 3.17Å; E460-R501 IonicContact OE1-NH1 2.68Å; E460-R501 PolarHBondContact OE1-NH1 3.33Å; E460-R501 VanDerWaalsContact OE1-NH1 3.12Å; E460-R501 IonicContact OE2-CZ 3.58Å; E460-R501 IonicContact OE2-NH1 3.38Å; E460-R501 PolarHBondContact OE2-NH1 2.85Å; N498-R501 HydrophobicContact CB-CG 4.44Å; N498-R501 WeakPolarHBondContact O-CB 3.46Å; N498-R501 WeakPolarHBondContact O-CG 3.35Å; N498-R501 PolarHBondContact O-N 3.46Å; C499-R501 PolarHBondContact O-N 2.95Å; C499-R501 VanDerWaalsContact O-N 3.15Å
502Y92.8Very high94Very high2 Ų221.1 Ų21.11%0.00811%0.114CC..  trans-114.393179.3-45.9-59.9000110.6K29 I459 C499 S500 S504 D507 A511 D513 C525K29-Y502 HydrophobicContact CD-CE1 4.12Å; I459-Y502 WeakPolarHBondContact CG2-OH 3.2Å; C499-Y502 WeakPolarHBondContact O-CD2 3.43Å; C499-Y502 PolarHBondContact O-N 3.05Å; S500-Y502 PolarHBondContact O-N 3.47Å; Y502-S504 VanDerWaalsContact C-N 3.29Å; Y502-S504 PolarHBondContact O-N 2.81Å; Y502-D507 WeakPolarHBondContact CA-OD2 3.45Å; Y502-A511 HydrophobicContact CD1-CB 3.63Å; Y502-A511 HydrophobicContact CD2-CB 3.97Å; Y502-A511 HydrophobicContact CE1-CB 3.42Å; Y502-A511 VanDerWaalsContact CE1-CB 3.42Å; Y502-A511 HydrophobicContact CE2-CB 3.75Å; Y502-A511 HydrophobicContact CG-CB 3.92Å; Y502-A511 VanDerWaalsContact CZ-CB 3.49Å; Y502-D513 HydrophobicContact CE2-CB 4.33Å; Y502-C525 WeakPolarHBondContact O-CB 3.44Å
503Q89.4Confident94Very high99 Ų9921.2 Ų21.246%0.46311%0.114SC..  trans-81.30.8-163-63-178.6-10.800115.1P561Q503-P561 HydrophobicContact CB-CG 3.81Å; Q503-P561 HydrophobicContact CG-CG 4.48Å
504S91.2Very high93.9Very high15 Ų1521 Ų2111%0.10511%0.113CC..SBendtrans-153.7159.9-176.7630000111.8Y502 D507 C508 W518Y502-S504 VanDerWaalsContact C-N 3.29Å; Y502-S504 PolarHBondContact O-N 2.81Å; S504-D507 PolarHBondContact O-N 3.1Å; S504-C508 WeakPolarHBondContact O-CB 3.33Å; S504-C508 PolarHBondContact O-N 3.17Å; S504-W518 VanDerWaalsContact CA-CZ3 3.44Å
505Q91.3Very high94Very high54 Ų5421.1 Ų21.125%0.25211%0.113SC..Hα-helixtrans-52.7-47.6-179.2-174.2167.239.500113.7C508 L509 W518 N520 S539 F554Q505-C508 PolarHBondContact O-N 2.8Å; Q505-L509 HydrophobicContact CG-CD1 4.04Å; Q505-L509 VanDerWaalsContact O-CG 3.31Å; Q505-L509 WeakPolarHBondContact O-CG 3.46Å; Q505-L509 PolarHBondContact O-N 3.46Å; Q505-L509 VanDerWaalsContact O-N 3.08Å; Q505-W518 VanDerWaalsContact CA-CD2 3.43Å; Q505-W518 HydrophobicContact CB-CD2 3.66Å; Q505-W518 HydrophobicContact CB-CE3 4.26Å; Q505-W518 HydrophobicContact CB-CG 3.82Å; Q505-W518 HydrophobicContact CB-CZ2 4.07Å; Q505-W518 HydrophobicContact CG-CB 4.21Å; Q505-W518 HydrophobicContact CG-CD2 4.1Å; Q505-W518 HydrophobicContact CG-CG 3.67Å; Q505-W518 VanDerWaalsContact N-CZ3 3.31Å; Q505-W518 VanDerWaalsContact NE2-CD1 3.3Å; Q505-N520 PolarHBondContact NE2-OD1 3.22Å; Q505-S539 PolarHBondContact NE2-OG 2.85Å; Q505-F554 HydrophobicContact CG-CE1 4.46Å
506P92.5Very high94.1Very high4 Ų419.5 Ų19.53%0.02610%0.103CC..Hα-helixtrans-69-39-178.9-12.226.6000111.9C508 L509 L510 F554 V558 V642 F644P506-C508 VanDerWaalsContact C-N 3.33Å; P506-C508 PolarHBondContact O-N 3.47Å; P506-L509 PolarHBondContact O-N 2.8Å; P506-L510 HydrophobicContact CB-CD1 4.48Å; P506-L510 WeakPolarHBondContact O-CB 3.24Å; P506-L510 WeakPolarHBondContact O-CG 3.37Å; P506-L510 PolarHBondContact O-N 3.12Å; P506-F554 HydrophobicContact CB-CD2 4.19Å; P506-F554 HydrophobicContact CB-CE2 3.85Å; P506-F554 HydrophobicContact CB-CZ 4.03Å; P506-F554 HydrophobicContact CG-CD1 3.88Å; P506-F554 HydrophobicContact CG-CD2 4.04Å; P506-F554 HydrophobicContact CG-CE1 3.77Å; P506-F554 HydrophobicContact CG-CE2 3.92Å; P506-F554 HydrophobicContact CG-CG 4.01Å; P506-F554 HydrophobicContact CG-CZ 3.79Å; P506-V558 HydrophobicContact CG-CG2 3.89Å; P506-V642 HydrophobicContact CB-CB 4.45Å; P506-V642 HydrophobicContact CB-CG1 3.69Å; P506-V642 HydrophobicContact CB-CG2 4.3Å; P506-V642 HydrophobicContact CG-CG1 3.97Å; P506-F644 HydrophobicContact CB-CE1 4.06Å; P506-F644 HydrophobicContact CB-CZ 3.81Å; P506-F644 HydrophobicContact CG-CE1 4.36Å
507D93.2Very high94.1Very high10 Ų1019.5 Ų19.55%0.05310%0.103CC..Hα-helixtrans-64.7-37.7177.7-174.724.6000111.8R28 K29 Y502 S504 A511 F644R28-D507 IonicContact CZ-OD1 2.68Å; R28-D507 VanDerWaalsContact CZ-OD1 3.27Å; R28-D507 PolarHBondContact NH1-O 3.44Å; R28-D507 IonicContact NH1-OD1 2.89Å; R28-D507 PolarHBondContact NH1-OD1 2.83Å; R28-D507 IonicContact NH2-OD1 2.84Å; R28-D507 PolarHBondContact NH2-OD1 2.93Å; K29-D507 VanDerWaalsContact CE-OD1 3.31Å; K29-D507 WeakPolarHBondContact CE-OD1 3.24Å; K29-D507 IonicContact NZ-OD1 2.68Å; K29-D507 PolarHBondContact NZ-OD1 2.81Å; K29-D507 IonicContact NZ-OD2 2.8Å; K29-D507 PolarHBondContact NZ-OD2 2.84Å; Y502-D507 WeakPolarHBondContact CA-OD2 3.45Å; S504-D507 PolarHBondContact O-N 3.1Å; D507-A511 VanDerWaalsContact O-CB 3.29Å; D507-A511 WeakPolarHBondContact O-CB 3.49Å; D507-A511 PolarHBondContact O-N 2.94Å; D507-F644 HydrophobicContact CB-CE1 4.01Å; D507-F644 HydrophobicContact CB-CZ 4.14Å
508C95.2Very high94.2Very high5 Ų520.6 Ų20.63%0.03411%0.106CC..Hα-helixtrans-65.9-38.5175.5-172.70000112.6S504 Q505 P506 W518 C525S504-C508 WeakPolarHBondContact O-CB 3.33Å; S504-C508 PolarHBondContact O-N 3.17Å; Q505-C508 PolarHBondContact O-N 2.8Å; P506-C508 VanDerWaalsContact C-N 3.33Å; P506-C508 PolarHBondContact O-N 3.47Å; C508-W518 HydrophobicContact CB-CB 4.13Å; C508-W518 HydrophobicContact CB-CE3 4Å; C508-W518 PolarHBondContact SG-N 3.1Å; C508-C525 HydrophobicContact CB-CB 3.56Å; C508-C525 WeakPolarHBondContact CB-SG 3.47Å; C508-C525 WeakPolarHBondContact SG-CB 3.48Å; C508-C525 CovalentContact SG-SG 2.03Å; C508-C525 PolarHBondContact SG-SG 3.09Å
509L94.8Very high94.2Very high6 Ų619.7 Ų19.73%0.03110%0.102CC..Hα-helixtrans-74.8-43.9175.7-64.8174.3000111.8Q505 P506 A511 R512 S539 D541 F547 F554Q505-L509 HydrophobicContact CG-CD1 4.04Å; Q505-L509 VanDerWaalsContact O-CG 3.31Å; Q505-L509 WeakPolarHBondContact O-CG 3.46Å; Q505-L509 PolarHBondContact O-N 3.46Å; Q505-L509 VanDerWaalsContact O-N 3.08Å; P506-L509 PolarHBondContact O-N 2.8Å; L509-A511 VanDerWaalsContact C-N 3.25Å; L509-A511 PolarHBondContact O-N 3.48Å; L509-R512 PolarHBondContact O-N 2.88Å; L509-R512 VanDerWaalsContact O-N 3.12Å; L509-S539 WeakPolarHBondContact CD2-O 3.26Å; L509-D541 HydrophobicContact CD2-CB 4.22Å; L509-F547 HydrophobicContact CB-CE2 4Å; L509-F547 HydrophobicContact CB-CZ 4.01Å; L509-F547 HydrophobicContact CD1-CZ 4.49Å; L509-F554 HydrophobicContact CD1-CZ 4.49Å
510L94.9Very high94Very high5 Ų523 Ų233%0.02612%0.119CC..Hα-helixtrans-69.7-19.8178.9-70169.9000113.3R28 P506 R512 L544 F547 E639 Q640 V642 F644R28-L510 VanDerWaalsContact CD-O 3.27Å; R28-L510 WeakPolarHBondContact CD-O 3.45Å; R28-L510 PolarHBondContact NE-O 3.18Å; P506-L510 HydrophobicContact CB-CD1 4.48Å; P506-L510 WeakPolarHBondContact O-CB 3.24Å; P506-L510 WeakPolarHBondContact O-CG 3.37Å; P506-L510 PolarHBondContact O-N 3.12Å; L510-R512 PolarHBondContact O-N 3.25Å; L510-L544 HydrophobicContact CD2-CD2 4.05Å; L510-F547 HydrophobicContact CD1-CE1 4.36Å; L510-F547 HydrophobicContact CD2-CD1 4.13Å; L510-F547 HydrophobicContact CD2-CE1 3.68Å; L510-F547 HydrophobicContact CD2-CE2 4.3Å; L510-F547 HydrophobicContact CD2-CZ 3.78Å; L510-F547 HydrophobicContact CG-CE1 3.96Å; L510-F547 HydrophobicContact CG-CZ 3.84Å; L510-E639 HydrophobicContact CD1-CB 4.2Å; L510-E639 HydrophobicContact CD1-CG 4.18Å; L510-Q640 HydrophobicContact CD2-CB 3.74Å; L510-Q640 HydrophobicContact CD2-CG 3.62Å; L510-V642 HydrophobicContact CD1-CB 4.37Å; L510-V642 HydrophobicContact CD1-CG2 4.23Å; L510-F644 HydrophobicContact CD1-CE2 4.09Å; L510-F644 HydrophobicContact CD1-CZ 4.07Å
511A95.8Very high94Very high0 Ų026 Ų260%012%0.124CC..THydrogen-bonded Turntrans-61.9-25.316900000113.5R28 Y502 D507 L509 D513R28-A511 VanDerWaalsContact NH1-CA 3.35Å; Y502-A511 HydrophobicContact CD1-CB 3.63Å; Y502-A511 HydrophobicContact CD2-CB 3.97Å; Y502-A511 HydrophobicContact CE1-CB 3.42Å; Y502-A511 VanDerWaalsContact CE1-CB 3.42Å; Y502-A511 HydrophobicContact CE2-CB 3.75Å; Y502-A511 HydrophobicContact CG-CB 3.92Å; Y502-A511 VanDerWaalsContact CZ-CB 3.49Å; D507-A511 VanDerWaalsContact O-CB 3.29Å; D507-A511 WeakPolarHBondContact O-CB 3.49Å; D507-A511 PolarHBondContact O-N 2.94Å; L509-A511 VanDerWaalsContact C-N 3.25Å; L509-A511 PolarHBondContact O-N 3.48Å; A511-D513 HydrophobicContact CB-CB 4.46Å; A511-D513 PolarHBondContact O-N 2.95Å
512R95.8Very high94Very high21 Ų2126.3 Ų26.38%0.07914%0.14CC..  trans49.229.7-177.5-53.117280.4-179.99.1112.9L450 L452 E455 L509 L510 L542 L544L450-R512 VanDerWaalsContact CD2-O 3.26Å; L450-R512 WeakPolarHBondContact CD2-O 3.28Å; L452-R512 VanDerWaalsContact CD1-CZ 3.48Å; E455-R512 IonicContact OE1-NH1 3.73Å; E455-R512 PolarHBondContact OE1-NH1 2.89Å; L509-R512 PolarHBondContact O-N 2.88Å; L509-R512 VanDerWaalsContact O-N 3.12Å; L510-R512 PolarHBondContact O-N 3.25Å; R512-L542 VanDerWaalsContact C-CD2 3.47Å; R512-L542 PolarHBondContact NE-O 2.85Å; R512-L542 PolarHBondContact NH2-O 3.08Å; R512-L542 WeakPolarHBondContact O-CD2 3.46Å; R512-L544 HydrophobicContact CG-CD2 3.95Å; R512-L544 HydrophobicContact CG-CG 4.2Å
513D97.1Very high93.9Very high2 Ų235.9 Ų35.91%0.01118%0.177CC..  trans-82.8118.5-177.6-173-36.8000109.7R448 I459 Y502 A511 Y515 C516 Q540R448-D513 IonicContact CZ-OD2 3.89Å; R448-D513 IonicContact NH1-OD2 3.33Å; R448-D513 PolarHBondContact NH1-OD2 3.17Å; R448-D513 IonicContact NH2-OD1 2.68Å; R448-D513 PolarHBondContact NH2-OD1 2.68Å; R448-D513 IonicContact NH2-OD2 3.73Å; R448-D513 PolarHBondContact NH2-OD2 2.71Å; I459-D513 HydrophobicContact CD1-CB 4.32Å; I459-D513 HydrophobicContact CG2-CB 4.32Å; Y502-D513 HydrophobicContact CE2-CB 4.33Å; A511-D513 HydrophobicContact CB-CB 4.46Å; A511-D513 PolarHBondContact O-N 2.95Å; D513-Y515 PolarHBondContact O-N 3.02Å; D513-Y515 VanDerWaalsContact OD1-CD2 3.3Å; D513-Y515 WeakPolarHBondContact OD1-CD2 3.43Å; D513-Y515 PolarHBondContact OD1-N 3.11Å; D513-C516 HydrophobicContact CB-CB 3.97Å; D513-C516 VanDerWaalsContact CG-SG 3.5Å; D513-C516 PolarHBondContact O-N 3.37Å; D513-C516 VanDerWaalsContact O-N 3.08Å; D513-Q540 PolarHBondContact O-NE2 3.33Å
514P96.4Very high94.1Very high1 Ų133.1 Ų33.11%0.00617%0.171CC..THydrogen-bonded Turntrans-66.9-21.4-173.130.4-38.6000113.6V426 M436 L450 Q540 L542V426-P514 HydrophobicContact CG1-CB 3.62Å; V426-P514 HydrophobicContact CG1-CG 3.58Å; V426-P514 HydrophobicContact CG2-CB 4.06Å; M436-P514 HydrophobicContact SD-CG 4.26Å; L450-P514 HydrophobicContact CD1-CB 4.31Å; L450-P514 HydrophobicContact CD1-CG 3.88Å; P514-Q540 PolarHBondContact O-NE2 2.7Å; P514-L542 HydrophobicContact CB-CD1 4.08Å; P514-L542 HydrophobicContact CB-CD2 4.5Å
515Y96.6Very high94.3Very high10 Ų1032.9 Ų32.94%0.03917%0.169CC..THydrogen-bonded Turntrans-86.5-11.8176.7-49.4-81.8000112.8D424 V426 M436 F438 L496 A497 D513 R527 I528D424-Y515 VanDerWaalsContact CB-OH 3.29Å; D424-Y515 WeakPolarHBondContact CB-OH 3.29Å; D424-Y515 PolarHBondContact OD2-OH 3.16Å; V426-Y515 HydrophobicContact CB-CE1 3.95Å; V426-Y515 HydrophobicContact CG1-CE1 4.37Å; V426-Y515 HydrophobicContact CG2-CD1 3.8Å; V426-Y515 HydrophobicContact CG2-CE1 3.75Å; M436-Y515 HydrophobicContact CG-CE2 3.89Å; F438-Y515 HydrophobicContact CZ-CE2 4.04Å; L496-Y515 HydrophobicContact CB-CE1 4.2Å; L496-Y515 HydrophobicContact CB-CE2 4.09Å; L496-Y515 HydrophobicContact CD1-CE1 4.05Å; A497-Y515 HydrophobicContact CB-CD2 3.77Å; A497-Y515 HydrophobicContact CB-CG 4.01Å; D513-Y515 PolarHBondContact O-N 3.02Å; D513-Y515 VanDerWaalsContact OD1-CD2 3.3Å; D513-Y515 WeakPolarHBondContact OD1-CD2 3.43Å; D513-Y515 PolarHBondContact OD1-N 3.11Å; Y515-R527 WeakPolarHBondContact O-CA 3.46Å; Y515-I528 WeakPolarHBondContact O-CG1 3.41Å; Y515-I528 PolarHBondContact O-N 3.16Å
516C97Very high94.5Very high1 Ų131.9 Ų31.91%0.00717%0.166CC..EExtended strand (participates in β ladder)trans-108.4142-173.8-58.80000112.5C499 D513 V526 Q540C499-C516 WeakPolarHBondContact CA-SG 3.31Å; C499-C516 HydrophobicContact CB-CB 3.77Å; C499-C516 WeakPolarHBondContact CB-SG 3.35Å; C499-C516 WeakPolarHBondContact SG-CA 3.48Å; C499-C516 WeakPolarHBondContact SG-CB 3.46Å; C499-C516 CovalentContact SG-SG 2.03Å; C499-C516 PolarHBondContact SG-SG 2.83Å; D513-C516 HydrophobicContact CB-CB 3.97Å; D513-C516 VanDerWaalsContact CG-SG 3.5Å; D513-C516 PolarHBondContact O-N 3.37Å; D513-C516 VanDerWaalsContact O-N 3.08Å; C516-V526 WeakPolarHBondContact CA-O 3.37Å; C516-Q540 PolarHBondContact O-NE2 3.15Å
517A96.8Very high94.7Very high1 Ų133.3 Ų33.31%0.00817%0.171CC..EExtended strand (participates in β ladder)trans-142.4152.7169.400000110.9L429 V526 I528 L538 Q540L429-A517 HydrophobicContact CD1-CB 3.69Å; L429-A517 HydrophobicContact CG-CB 4.5Å; A517-V526 PolarHBondContact N-O 3.36Å; A517-V526 WeakPolarHBondContact O-CG2 3.37Å; A517-V526 PolarHBondContact O-N 2.79Å; A517-I528 HydrophobicContact CB-CD1 4.03Å; A517-I528 HydrophobicContact CB-CG1 3.73Å; A517-L538 HydrophobicContact CB-CB 4.03Å; A517-L538 HydrophobicContact CB-CD1 4.42Å; A517-Q540 HydrophobicContact CB-CB 4.33Å
518W95.9Very high94.7Very high24 Ų2434.8 Ų34.89%0.09118%0.179CC..EExtended strand (participates in β ladder)trans-84.7117.4173.6178.9-93000110.4S504 Q505 C508 R523 A524 C525 L538 S539S504-W518 VanDerWaalsContact CA-CZ3 3.44Å; Q505-W518 VanDerWaalsContact CA-CD2 3.43Å; Q505-W518 HydrophobicContact CB-CD2 3.66Å; Q505-W518 HydrophobicContact CB-CE3 4.26Å; Q505-W518 HydrophobicContact CB-CG 3.82Å; Q505-W518 HydrophobicContact CB-CZ2 4.07Å; Q505-W518 HydrophobicContact CG-CB 4.21Å; Q505-W518 HydrophobicContact CG-CD2 4.1Å; Q505-W518 HydrophobicContact CG-CG 3.67Å; Q505-W518 VanDerWaalsContact N-CZ3 3.31Å; Q505-W518 VanDerWaalsContact NE2-CD1 3.3Å; C508-W518 HydrophobicContact CB-CB 4.13Å; C508-W518 HydrophobicContact CB-CE3 4Å; C508-W518 PolarHBondContact SG-N 3.1Å; W518-R523 WeakPolarHBondContact CH2-O 3.22Å; W518-R523 HydrophobicContact CZ2-CB 4.12Å; W518-R523 WeakPolarHBondContact CZ2-O 3.23Å; W518-A524 VanDerWaalsContact CZ3-C 3.48Å; W518-C525 HydrophobicContact CE3-CB 4.14Å; W518-L538 CarbonylContact O-C 3.48Å; W518-L538 WeakPolarHBondContact O-CA 3.42Å; W518-S539 PolarHBondContact N-O 3.2Å; W518-S539 PolarHBondContact O-N 3.3Å; W518-S539 PolarHBondContact O-OG 2.95Å
519D95.2Very high94.4Very high18 Ų1838.2 Ų38.210%0.09620%0.197CC..EExtended strand (participates in β ladder)trans-78.4116.2170.1-179-2.8000109.6E521 G522 R523 A524 V526 H531 S537 L538D519-E521 VanDerWaalsContact C-N 3.32Å; D519-E521 PolarHBondContact OD1-N 3.46Å; D519-G522 VanDerWaalsContact CG-N 3.25Å; D519-G522 PolarHBondContact OD1-N 2.83Å; D519-G522 VanDerWaalsContact OD1-N 3.08Å; D519-G522 PolarHBondContact OD2-N 3.24Å; D519-R523 VanDerWaalsContact O-CA 3.25Å; D519-R523 WeakPolarHBondContact O-CA 3.37Å; D519-R523 PolarHBondContact O-N 3.21Å; D519-A524 PolarHBondContact N-O 3.49Å; D519-A524 PolarHBondContact O-N 2.85Å; D519-V526 HydrophobicContact CB-CG1 4.34Å; D519-V526 HydrophobicContact CB-CG2 4.04Å; D519-H531 IonicContact OD2-CE1 3.38Å; D519-H531 PolarHBondContact OD2-CE1 2.97Å; D519-H531 IonicContact OD2-ND1 3.87Å; D519-S537 PolarHBondContact OD1-OG 2.97Å; D519-L538 HydrophobicContact CB-CD2 3.81Å
520N91.2Very high94.2Very high74 Ų7443.4 Ų43.440%0.39622%0.224SC..THydrogen-bonded Turntrans-74.6-22.2-179.4-68.5-81.2000113.1Q505 S537 S539Q505-N520 PolarHBondContact NE2-OD1 3.22Å; N520-S537 WeakPolarHBondContact CB-O 3.33Å; N520-S537 PolarHBondContact N-O 3.03Å; N520-S537 PolarHBondContact ND2-O 3.41Å; N520-S539 PolarHBondContact ND2-OG 3.33Å
521E91Very high93.9Very high150 Ų15045.2 Ų45.270%0.70123%0.232SC*.THydrogen-bonded Turntrans-86.9-53.2178-68.3172.6-15400110.3D519 R523 S537D519-E521 VanDerWaalsContact C-N 3.32Å; D519-E521 PolarHBondContact OD1-N 3.46Å; E521-R523 PolarHBondContact O-N 2.75Å; E521-S537 WeakPolarHBondContact OE1-CB 3.42Å
522G89.3Confident93.4Very high50 Ų5057 Ų5752%0.51528%0.277SS..THydrogen-bonded Turntrans-69.4-14.3175.500000114.8D519 A524D519-G522 VanDerWaalsContact CG-N 3.25Å; D519-G522 PolarHBondContact OD1-N 2.83Å; D519-G522 VanDerWaalsContact OD1-N 3.08Å; D519-G522 PolarHBondContact OD2-N 3.24Å; G522-A524 VanDerWaalsContact C-N 3.3Å; G522-A524 PolarHBondContact O-N 3.48Å
523R91.1Very high92.7Very high203 Ų20358.2 Ų58.277%0.76630%0.296SS*.THydrogen-bonded Turntrans52.243.5-178.1-59.8-177176.3-171.1-0.2113.4W518 D519 E521W518-R523 WeakPolarHBondContact CH2-O 3.22Å; W518-R523 HydrophobicContact CZ2-CB 4.12Å; W518-R523 WeakPolarHBondContact CZ2-O 3.23Å; D519-R523 VanDerWaalsContact O-CA 3.25Å; D519-R523 WeakPolarHBondContact O-CA 3.37Å; D519-R523 PolarHBondContact O-N 3.21Å; E521-R523 PolarHBondContact O-N 2.75Å
524A93.9Very high92.1Very high41 Ų4161.3 Ų61.334%0.33932%0.317SS..EExtended strand (participates in β ladder)trans-143.3155.2-178.800000111.5W518 D519 G522 V526W518-A524 VanDerWaalsContact CZ3-C 3.48Å; D519-A524 PolarHBondContact N-O 3.49Å; D519-A524 PolarHBondContact O-N 2.85Å; G522-A524 VanDerWaalsContact C-N 3.3Å; G522-A524 PolarHBondContact O-N 3.48Å; A524-V526 HydrophobicContact CB-CG1 4.26Å
525C95.9Very high91.6Very high10 Ų1065.9 Ų65.97%0.06835%0.346CS..EExtended strand (participates in β ladder)trans-83.8116.1167.8-162.60000109.3C499 Y502 C508 W518C499-C525 WeakPolarHBondContact O-CB 3.46Å; Y502-C525 WeakPolarHBondContact O-CB 3.44Å; C508-C525 HydrophobicContact CB-CB 3.56Å; C508-C525 WeakPolarHBondContact CB-SG 3.47Å; C508-C525 WeakPolarHBondContact SG-CB 3.48Å; C508-C525 CovalentContact SG-SG 2.03Å; C508-C525 PolarHBondContact SG-SG 3.09Å; W518-C525 HydrophobicContact CE3-CB 4.14Å
526V96Very high91.1Very high33 Ų3370.2 Ų70.220%0.238%0.378CS..EExtended strand (participates in β ladder)trans-118154.6-171.3-62.30000111.3C516 A517 D519 A524 H531 L538C516-V526 WeakPolarHBondContact CA-O 3.37Å; A517-V526 PolarHBondContact N-O 3.36Å; A517-V526 WeakPolarHBondContact O-CG2 3.37Å; A517-V526 PolarHBondContact O-N 2.79Å; D519-V526 HydrophobicContact CB-CG1 4.34Å; D519-V526 HydrophobicContact CB-CG2 4.04Å; A524-V526 HydrophobicContact CB-CG1 4.26Å; V526-H531 HydrophobicContact CG2-CB 4.42Å; V526-L538 HydrophobicContact CG2-CD2 3.81Å
527R94.8Very high90.8Very high34 Ų3470.6 Ų70.613%0.12838%0.38CS..EExtended strand (participates in β ladder)trans-71.6125.4166.8-90.1-177.164.7162.9-7.2109.6K481 C499 Y515 D529 L530 H531K481-R527 VanDerWaalsContact CB-NH2 3.29Å; C499-R527 WeakPolarHBondContact SG-CG 3.35Å; Y515-R527 WeakPolarHBondContact O-CA 3.46Å; R527-D529 VanDerWaalsContact C-N 3.27Å; R527-D529 WeakPolarHBondContact CB-OD1 3.37Å; R527-D529 IonicContact CZ-OD1 3.17Å; R527-D529 IonicContact CZ-OD2 3.27Å; R527-D529 IonicContact NE-OD1 2.74Å; R527-D529 PolarHBondContact NE-OD1 2.6Å; R527-D529 IonicContact NE-OD2 2.78Å; R527-D529 IonicContact NH2-OD1 2.76Å; R527-D529 PolarHBondContact NH2-OD1 2.85Å; R527-D529 IonicContact NH2-OD2 2.81Å; R527-D529 PolarHBondContact NH2-OD2 2.81Å; R527-D529 PolarHBondContact O-N 3.36Å; R527-L530 HydrophobicContact CB-CB 4.11Å; R527-L530 HydrophobicContact CB-CD1 4.08Å; R527-L530 HydrophobicContact CB-CG 4.03Å; R527-L530 PolarHBondContact O-N 3.32Å; R527-H531 PolarHBondContact O-N 2.89Å; R527-H531 VanDerWaalsContact O-N 3.16Å
528I93.9Very high90.7Very high41 Ų4171.3 Ų71.321%0.2138%0.384CS..G310 helixtrans-60.8-39-178.3-63.3165.2000110.7L429 Y515 A517 L530 H531L429-I528 HydrophobicContact CD2-CD1 3.94Å; L429-I528 HydrophobicContact CD2-CG1 4.29Å; L429-I528 HydrophobicContact CD2-CG2 3.98Å; L429-I528 HydrophobicContact CG-CD1 3.95Å; Y515-I528 WeakPolarHBondContact O-CG1 3.41Å; Y515-I528 PolarHBondContact O-N 3.16Å; A517-I528 HydrophobicContact CB-CD1 4.03Å; A517-I528 HydrophobicContact CB-CG1 3.73Å; I528-L530 VanDerWaalsContact C-N 3.27Å; I528-L530 PolarHBondContact O-N 2.85Å; I528-H531 PolarHBondContact O-N 2.7Å
529D89.9Confident90.6Very high78 Ų7870.4 Ų70.442%0.41738%0.381SS..G310 helixtrans-75-12.1-178.370-52.4000114.5R527R527-D529 VanDerWaalsContact C-N 3.27Å; R527-D529 WeakPolarHBondContact CB-OD1 3.37Å; R527-D529 IonicContact CZ-OD1 3.17Å; R527-D529 IonicContact CZ-OD2 3.27Å; R527-D529 IonicContact NE-OD1 2.74Å; R527-D529 PolarHBondContact NE-OD1 2.6Å; R527-D529 IonicContact NE-OD2 2.78Å; R527-D529 IonicContact NH2-OD1 2.76Å; R527-D529 PolarHBondContact NH2-OD1 2.85Å; R527-D529 IonicContact NH2-OD2 2.81Å; R527-D529 PolarHBondContact NH2-OD2 2.81Å; R527-D529 PolarHBondContact O-N 3.36Å
530L90.3Very high90.6Very high115 Ų11570.5 Ų70.560%0.60238%0.381SS*.G310 helixtrans-107.9-7.1176.4-57.8-177.9000113R527 I528R527-L530 HydrophobicContact CB-CB 4.11Å; R527-L530 HydrophobicContact CB-CD1 4.08Å; R527-L530 HydrophobicContact CB-CG 4.03Å; R527-L530 PolarHBondContact O-N 3.32Å; I528-L530 VanDerWaalsContact C-N 3.27Å; I528-L530 PolarHBondContact O-N 2.85Å
531H88.9Confident90.7Very high43 Ų4367.7 Ų67.720%0.19937%0.366CS..  trans-74132.1-178.8-17681.4000111.1D519 V526 R527 I528 G533 L538D519-H531 IonicContact OD2-CE1 3.38Å; D519-H531 PolarHBondContact OD2-CE1 2.97Å; D519-H531 IonicContact OD2-ND1 3.87Å; V526-H531 HydrophobicContact CG2-CB 4.42Å; R527-H531 PolarHBondContact O-N 2.89Å; R527-H531 VanDerWaalsContact O-N 3.16Å; I528-H531 PolarHBondContact O-N 2.7Å; H531-G533 PolarHBondContact CD2-N 2.99Å; H531-G533 VanDerWaalsContact CD2-N 3.3Å; H531-G533 PolarHBondContact CD2-O 2.92Å; H531-G533 VanDerWaalsContact NE2-C 3.29Å; H531-G533 WeakPolarHBondContact NE2-CA 3.48Å; H531-G533 PolarHBondContact NE2-N 3.33Å; H531-G533 VanDerWaalsContact NE2-N 3.19Å; H531-L538 HydrophobicContact CB-CD1 4.42Å
532R83.9Confident90.9Very high247 Ų24760.8 Ų60.893%0.93233%0.334SS*.  trans-108.1-5.3-176.8-61-172.4-178.8-160.60.5114.6
533G81.1Confident90.9Very high47 Ų4762.1 Ų62.149%0.48533%0.328SS..SBendtrans-85.4-168.6174.900000112.4H531H531-G533 PolarHBondContact CD2-N 2.99Å; H531-G533 VanDerWaalsContact CD2-N 3.3Å; H531-G533 PolarHBondContact CD2-O 2.92Å; H531-G533 VanDerWaalsContact NE2-C 3.29Å; H531-G533 WeakPolarHBondContact NE2-CA 3.48Å; H531-G533 PolarHBondContact NE2-N 3.33Å; H531-G533 VanDerWaalsContact NE2-N 3.19Å
534S84Confident90.9Very high66 Ų6653.2 Ų53.246%0.46230%0.295SS..  trans-74.6130.2176.1-176.10000110.9S536 S537S534-S536 WeakPolarHBondContact CB-OG 3.47Å; S534-S536 PolarHBondContact O-N 3.11Å; S534-S536 PolarHBondContact OG-N 3.25Å; S534-S536 PolarHBondContact OG-OG 2.95Å; S534-S537 PolarHBondContact O-N 2.95Å; S534-S537 PolarHBondContact O-OG 3.22Å
535T86.6Confident90.5Very high98 Ų9853.9 Ų53.960%0.60129%0.293SS*.G310 helixtrans-60.1-13.1173.252.90000113.4S537 L538T535-S537 VanDerWaalsContact C-N 3.33Å; T535-L538 HydrophobicContact CG2-CD1 4.38Å; T535-L538 WeakPolarHBondContact O-CB 3.38Å; T535-L538 PolarHBondContact O-N 3.07Å
536S87Confident89.9Confident101 Ų10158.6 Ų58.671%0.70631%0.309SS*.G310 helixtrans-69.9-20.6171.465.80000114.8S534 L538S534-S536 WeakPolarHBondContact CB-OG 3.47Å; S534-S536 PolarHBondContact O-N 3.11Å; S534-S536 PolarHBondContact OG-N 3.25Å; S534-S536 PolarHBondContact OG-OG 2.95Å; S536-L538 VanDerWaalsContact C-N 3.32Å
537S90Very high89.4Confident8 Ų858.1 Ų58.16%0.05631%0.305CS..G310 helixtrans-81.2-15.6173.679.50000112.3D519 N520 E521 S534 T535D519-S537 PolarHBondContact OD1-OG 2.97Å; N520-S537 WeakPolarHBondContact CB-O 3.33Å; N520-S537 PolarHBondContact N-O 3.03Å; N520-S537 PolarHBondContact ND2-O 3.41Å; E521-S537 WeakPolarHBondContact OE1-CB 3.42Å; S534-S537 PolarHBondContact O-N 2.95Å; S534-S537 PolarHBondContact O-OG 3.22Å; T535-S537 VanDerWaalsContact C-N 3.33Å
538L95.1Very high88.8Confident16 Ų1661.1 Ų61.18%0.08433%0.331CS..EExtended strand (participates in β ladder)trans-82.4150.5-175.5-58.1-176.6000112.3L429 A517 W518 D519 V526 H531 T535 S536L429-L538 HydrophobicContact CD1-CB 3.63Å; L429-L538 HydrophobicContact CD2-CD1 4.48Å; A517-L538 HydrophobicContact CB-CB 4.03Å; A517-L538 HydrophobicContact CB-CD1 4.42Å; W518-L538 CarbonylContact O-C 3.48Å; W518-L538 WeakPolarHBondContact O-CA 3.42Å; D519-L538 HydrophobicContact CB-CD2 3.81Å; V526-L538 HydrophobicContact CG2-CD2 3.81Å; H531-L538 HydrophobicContact CB-CD1 4.42Å; T535-L538 HydrophobicContact CG2-CD1 4.38Å; T535-L538 WeakPolarHBondContact O-CB 3.38Å; T535-L538 PolarHBondContact O-N 3.07Å; S536-L538 VanDerWaalsContact C-N 3.32Å
539S94Very high88.2Confident5 Ų567 Ų674%0.03535%0.35CS..EExtended strand (participates in β ladder)trans-139.9129.7177.650.80000112.4Q505 L509 W518 N520Q505-S539 PolarHBondContact NE2-OG 2.85Å; L509-S539 WeakPolarHBondContact CD2-O 3.26Å; W518-S539 PolarHBondContact N-O 3.2Å; W518-S539 PolarHBondContact O-N 3.3Å; W518-S539 PolarHBondContact O-OG 2.95Å; N520-S539 PolarHBondContact ND2-OG 3.33Å
540Q95.2Very high87.4Confident21 Ų2165.5 Ų65.510%0.09835%0.353CS..  trans-139.7155.3-180-165.2-176.653.800108.5L429 D513 P514 C516 A517 L542 R546L429-Q540 HydrophobicContact CB-CB 4.25Å; L429-Q540 HydrophobicContact CD1-CB 3.82Å; L429-Q540 HydrophobicContact CG-CB 4.09Å; D513-Q540 PolarHBondContact O-NE2 3.33Å; P514-Q540 PolarHBondContact O-NE2 2.7Å; C516-Q540 PolarHBondContact O-NE2 3.15Å; A517-Q540 HydrophobicContact CB-CB 4.33Å; Q540-L542 HydrophobicContact CG-CD2 3.79Å; Q540-L542 HydrophobicContact CG-CG 3.94Å; Q540-R546 PolarHBondContact O-NH2 3.35Å
541D93.1Very high86.6Confident14 Ų1467.7 Ų67.78%0.07536%0.358CS..  trans-153.368.5177.7-169.810.5000112.3L509 M543 L544 D545 R546 F547L509-D541 HydrophobicContact CD2-CB 4.22Å; D541-M543 PolarHBondContact O-N 2.91Å; D541-L544 PolarHBondContact O-N 2.04Å; D541-L544 PolarHBondContact OD1-N 2.81Å; D541-L544 WeakPolarHBondContact OD2-CA 3.49Å; D541-D545 VanDerWaalsContact CG-N 3.33Å; D541-D545 PolarHBondContact OD1-N 3.08Å; D541-D545 PolarHBondContact OD2-N 2.85Å; D541-D545 VanDerWaalsContact OD2-N 3.12Å; D541-R546 HydrophobicContact CB-CG 4.4Å; D541-R546 WeakPolarHBondContact OD2-CB 3.3Å; D541-R546 VanDerWaalsContact OD2-CG 3.22Å; D541-R546 WeakPolarHBondContact OD2-CG 3.41Å; D541-R546 PolarHBondContact OD2-N 2.92Å; D541-F547 WeakPolarHBondContact OD2-CD2 3.42Å
542L93.8Very high85.9Confident6 Ų666.9 Ų66.93%0.03136%0.359CS..THydrogen-bonded Turntrans-62.4-27.3-174.6-55.7177.9000113.4Y434 L450 L452 R512 P514 Q540Y434-L542 HydrophobicContact CD2-CD1 3.7Å; Y434-L542 HydrophobicContact CE1-CB 4.4Å; Y434-L542 HydrophobicContact CE1-CD1 4.43Å; Y434-L542 HydrophobicContact CE2-CD1 3.46Å; Y434-L542 VanDerWaalsContact CE2-CD1 3.46Å; Y434-L542 HydrophobicContact CG-CD1 4.31Å; L450-L542 HydrophobicContact CD2-CD2 4.47Å; L452-L542 WeakPolarHBondContact CD2-O 3.39Å; R512-L542 VanDerWaalsContact C-CD2 3.47Å; R512-L542 PolarHBondContact NE-O 2.85Å; R512-L542 PolarHBondContact NH2-O 3.08Å; R512-L542 WeakPolarHBondContact O-CD2 3.46Å; P514-L542 HydrophobicContact CB-CD1 4.08Å; P514-L542 HydrophobicContact CB-CD2 4.5Å; Q540-L542 HydrophobicContact CG-CD2 3.79Å; Q540-L542 HydrophobicContact CG-CG 3.94Å
543M91.2Very high85.1Confident78 Ų7862.2 Ų62.238%0.38435%0.345SS..THydrogen-bonded Turntrans-91.6-1.3177.9-61.6-56-61.200113.7Y434 L452 D541 D545Y434-M543 HydrophobicContact CE1-SD 4.19Å; L452-M543 HydrophobicContact CD2-SD 3.63Å; D541-M543 PolarHBondContact O-N 2.91Å; M543-D545 HydrophobicContact CB-CB 4.35Å; M543-D545 PolarHBondContact O-N 2.93Å
544L89.9Confident84.9Confident15 Ų1562.9 Ų62.98%0.07934%0.335CS..  trans52.235.9-170.9-57.9-179.9000113L510 R512 D541 R546 F547 S548 Q640L510-L544 HydrophobicContact CD2-CD2 4.05Å; R512-L544 HydrophobicContact CG-CD2 3.95Å; R512-L544 HydrophobicContact CG-CG 4.2Å; D541-L544 PolarHBondContact O-N 2.04Å; D541-L544 PolarHBondContact OD1-N 2.81Å; D541-L544 WeakPolarHBondContact OD2-CA 3.49Å; L544-R546 VanDerWaalsContact C-N 3.33Å; L544-R546 PolarHBondContact O-N 3.01Å; L544-F547 HydrophobicContact CB-CB 4.35Å; L544-F547 HydrophobicContact CB-CD2 4.15Å; L544-F547 HydrophobicContact CD2-CD2 3.71Å; L544-F547 HydrophobicContact CD2-CE2 3.84Å; L544-F547 HydrophobicContact CD2-CG 4.46Å; L544-F547 PolarHBondContact O-N 3.47Å; L544-S548 WeakPolarHBondContact O-CB 3.46Å; L544-S548 PolarHBondContact O-N 3.24Å; L544-S548 PolarHBondContact O-OG 2.69Å; L544-Q640 HydrophobicContact CD1-CG 4.25Å
545D85.9Confident83.8Confident56 Ų5666.4 Ų66.430%0.29935%0.349SS..Hα-helixtrans-73.4-26.6-172.6-137.1-18.3000111.5D541 M543 R549D541-D545 VanDerWaalsContact CG-N 3.33Å; D541-D545 PolarHBondContact OD1-N 3.08Å; D541-D545 PolarHBondContact OD2-N 2.85Å; D541-D545 VanDerWaalsContact OD2-N 3.12Å; M543-D545 HydrophobicContact CB-CB 4.35Å; M543-D545 PolarHBondContact O-N 2.93Å; D545-R549 WeakPolarHBondContact O-CB 3.48Å; D545-R549 WeakPolarHBondContact O-CD 3.09Å; D545-R549 WeakPolarHBondContact O-CG 3.45Å; D545-R549 PolarHBondContact O-N 2.8Å; D545-R549 IonicContact OD1-CZ 3.13Å; D545-R549 IonicContact OD1-NE 2.71Å; D545-R549 PolarHBondContact OD1-NE 2.72Å; D545-R549 IonicContact OD1-NH2 2.73Å; D545-R549 PolarHBondContact OD1-NH2 3.25Å; D545-R549 IonicContact OD2-CZ 3.79Å; D545-R549 IonicContact OD2-NH2 3.2Å; D545-R549 PolarHBondContact OD2-NH2 2.82Å
546R83.7Confident83.1Confident109 Ų10970 Ų7041%0.41136%0.356SS..Hα-helixtrans-74.9-39.2172.8-54.2173.1-165.8-1353.7111.1Q540 D541 L544 G550 K551 A552Q540-R546 PolarHBondContact O-NH2 3.35Å; D541-R546 HydrophobicContact CB-CG 4.4Å; D541-R546 WeakPolarHBondContact OD2-CB 3.3Å; D541-R546 VanDerWaalsContact OD2-CG 3.22Å; D541-R546 WeakPolarHBondContact OD2-CG 3.41Å; D541-R546 PolarHBondContact OD2-N 2.92Å; L544-R546 VanDerWaalsContact C-N 3.33Å; L544-R546 PolarHBondContact O-N 3.01Å; R546-G550 PolarHBondContact O-N 3.13Å; R546-K551 CarbonylContact O-C 3.56Å; R546-K551 WeakPolarHBondContact O-CA 3.48Å; R546-K551 PolarHBondContact O-N 2.93Å; R546-A552 HydrophobicContact CB-CB 4.06Å; R546-A552 PolarHBondContact O-N 2.63Å
547F85.4Confident82.3Confident23 Ų2368.5 Ų68.510%0.10134%0.343CS..Hα-helixtrans-68.9-52.9178.6-62.2-97.7000110.5L509 L510 D541 L544 R549 G550 A552 F554 Q640 V642L509-F547 HydrophobicContact CB-CE2 4Å; L509-F547 HydrophobicContact CB-CZ 4.01Å; L509-F547 HydrophobicContact CD1-CZ 4.49Å; L510-F547 HydrophobicContact CD1-CE1 4.36Å; L510-F547 HydrophobicContact CD2-CD1 4.13Å; L510-F547 HydrophobicContact CD2-CE1 3.68Å; L510-F547 HydrophobicContact CD2-CE2 4.3Å; L510-F547 HydrophobicContact CD2-CZ 3.78Å; L510-F547 HydrophobicContact CG-CE1 3.96Å; L510-F547 HydrophobicContact CG-CZ 3.84Å; D541-F547 WeakPolarHBondContact OD2-CD2 3.42Å; L544-F547 HydrophobicContact CB-CB 4.35Å; L544-F547 HydrophobicContact CB-CD2 4.15Å; L544-F547 HydrophobicContact CD2-CD2 3.71Å; L544-F547 HydrophobicContact CD2-CE2 3.84Å; L544-F547 HydrophobicContact CD2-CG 4.46Å; L544-F547 PolarHBondContact O-N 3.47Å; F547-R549 PolarHBondContact O-N 3.14Å; F547-R549 VanDerWaalsContact O-N 3.1Å; F547-G550 PolarHBondContact O-N 3.14Å; F547-A552 HydrophobicContact CB-CB 4.4Å; F547-A552 HydrophobicContact CD1-CB 3.68Å; F547-A552 HydrophobicContact CD2-CB 4.1Å; F547-A552 HydrophobicContact CE1-CB 3.89Å; F547-A552 HydrophobicContact CE2-CB 4.29Å; F547-A552 HydrophobicContact CG-CB 3.79Å; F547-A552 HydrophobicContact CZ-CB 4.19Å; F547-F554 HydrophobicContact CE1-CE2 4.09Å; F547-F554 HydrophobicContact CZ-CE2 4.3Å; F547-Q640 HydrophobicContact CD1-CB 4.11Å; F547-V642 HydrophobicContact CD1-CG2 4.39Å; F547-V642 HydrophobicContact CE1-CG2 3.82Å
548S81.9Confident81.8Confident97 Ų9769.6 Ų69.668%0.67835%0.35SS*.Hα-helixtrans-59.1-26.7-178.9-55.70000113.8L544L544-S548 WeakPolarHBondContact O-CB 3.46Å; L544-S548 PolarHBondContact O-N 3.24Å; L544-S548 PolarHBondContact O-OG 2.69Å
549R80.1Confident80.7Confident163 Ų16372.4 Ų72.462%0.61537%0.371SS*.THydrogen-bonded Turntrans-97.69.8177.6-59.4179-158.3-14912.6113.8D545 F547 K551D545-R549 WeakPolarHBondContact O-CB 3.48Å; D545-R549 WeakPolarHBondContact O-CD 3.09Å; D545-R549 WeakPolarHBondContact O-CG 3.45Å; D545-R549 PolarHBondContact O-N 2.8Å; D545-R549 IonicContact OD1-CZ 3.13Å; D545-R549 IonicContact OD1-NE 2.71Å; D545-R549 PolarHBondContact OD1-NE 2.72Å; D545-R549 IonicContact OD1-NH2 2.73Å; D545-R549 PolarHBondContact OD1-NH2 3.25Å; D545-R549 IonicContact OD2-CZ 3.79Å; D545-R549 IonicContact OD2-NH2 3.2Å; D545-R549 PolarHBondContact OD2-NH2 2.82Å; F547-R549 PolarHBondContact O-N 3.14Å; F547-R549 VanDerWaalsContact O-N 3.1Å; R549-K551 HydrophobicContact CB-CG 4.27Å; R549-K551 PolarHBondContact O-N 2.86Å
550G74.4Confident79.6Confident47 Ų4773.5 Ų73.549%0.48538%0.376SS..THydrogen-bonded Turntrans63.819.2-179.500000115R546 F547R546-G550 PolarHBondContact O-N 3.13Å; F547-G550 PolarHBondContact O-N 3.14Å
551K72.3Confident77.9Confident162 Ų16276.8 Ų76.870%0.70440%0.399SS*.  trans-89.9-24.3179.6-65.2-169.7175.7-170.30112.9R546 R549 K553R546-K551 CarbonylContact O-C 3.56Å; R546-K551 WeakPolarHBondContact O-CA 3.48Å; R546-K551 PolarHBondContact O-N 2.93Å; R549-K551 HydrophobicContact CB-CG 4.27Å; R549-K551 PolarHBondContact O-N 2.86Å; K551-K553 VanDerWaalsContact C-N 3.27Å; K551-K553 PolarHBondContact O-N 3.39Å
552A74.6Confident76.5Confident26 Ų2677.4 Ų77.422%0.21541%0.405CS..  trans-7777.817100000110R546 F547 F554R546-A552 HydrophobicContact CB-CB 4.06Å; R546-A552 PolarHBondContact O-N 2.63Å; F547-A552 HydrophobicContact CB-CB 4.4Å; F547-A552 HydrophobicContact CD1-CB 3.68Å; F547-A552 HydrophobicContact CD2-CB 4.1Å; F547-A552 HydrophobicContact CE1-CB 3.89Å; F547-A552 HydrophobicContact CE2-CB 4.29Å; F547-A552 HydrophobicContact CG-CB 3.79Å; F547-A552 HydrophobicContact CZ-CB 4.19Å; A552-F554 HydrophobicContact CB-CE2 4.06Å
553K67.5Low74.7Confident149 Ų14982.4 Ų82.465%0.64844%0.437SS*.  trans-93115.3175.6-71.3-164.8174.1-168.10110.9K551K551-K553 VanDerWaalsContact C-N 3.27Å; K551-K553 PolarHBondContact O-N 3.39Å
554F77.4Confident73.2Confident61 Ų6184.3 Ų84.327%0.26845%0.445SS..  trans-115.473.9171.8-60-71000108.2Q505 P506 L509 F547 A552 K556 V642Q505-F554 HydrophobicContact CG-CE1 4.46Å; P506-F554 HydrophobicContact CB-CD2 4.19Å; P506-F554 HydrophobicContact CB-CE2 3.85Å; P506-F554 HydrophobicContact CB-CZ 4.03Å; P506-F554 HydrophobicContact CG-CD1 3.88Å; P506-F554 HydrophobicContact CG-CD2 4.04Å; P506-F554 HydrophobicContact CG-CE1 3.77Å; P506-F554 HydrophobicContact CG-CE2 3.92Å; P506-F554 HydrophobicContact CG-CG 4.01Å; P506-F554 HydrophobicContact CG-CZ 3.79Å; L509-F554 HydrophobicContact CD1-CZ 4.49Å; F547-F554 HydrophobicContact CE1-CE2 4.09Å; F547-F554 HydrophobicContact CZ-CE2 4.3Å; A552-F554 HydrophobicContact CB-CE2 4.06Å; F554-K556 PolarHBondContact O-N 2.84Å; F554-V642 HydrophobicContact CB-CG1 4.47Å; F554-V642 HydrophobicContact CD2-CG1 4.2Å; F554-V642 HydrophobicContact CD2-CG2 3.72Å; F554-V642 HydrophobicContact CE2-CG2 4.18Å
555D61.1Low72Confident140 Ų14084.6 Ų84.675%0.74945%0.447SS*.  trans-65.63.8-169.5-56.9-38.5000114.8
556K72.1Confident70.9Confident174 Ų17485.6 Ų85.676%0.75746%0.458SS*.SBendtrans-135.5138.8173.6-65.8-175-179.5-179.30109.5F554 V558F554-K556 PolarHBondContact O-N 2.84Å; K556-V558 PolarHBondContact O-N 2.79Å
557P70.2Confident70.6Confident68 Ų6889.1 Ų89.144%0.44247%0.471SS..PPolyproline II helixtrans-58134.5175.7-23.233.1000112S559 Y636 K643P557-S559 PolarHBondContact O-N 3.39Å; P557-Y636 HydrophobicContact CB-CD1 3.91Å; P557-Y636 HydrophobicContact CB-CE1 3.47Å; P557-Y636 VanDerWaalsContact CB-CE1 3.47Å; P557-Y636 HydrophobicContact CG-CD1 4.46Å; P557-Y636 HydrophobicContact CG-CE1 3.79Å; P557-K643 VanDerWaalsContact CA-O 3.32Å; P557-K643 WeakPolarHBondContact CA-O 3.46Å
558V79.3Confident70.6Confident31 Ų3191.6 Ų91.619%0.18849%0.485CS..EExtended strand (participates in β ladder)trans-84.8116.3-177.4176.20000108.5P506 K556 K643 F644 Q645P506-V558 HydrophobicContact CG-CG2 3.89Å; K556-V558 PolarHBondContact O-N 2.79Å; V558-K643 PolarHBondContact N-O 3.33Å; V558-F644 HydrophobicContact CB-CD1 4.08Å; V558-F644 HydrophobicContact CG1-CD1 4.13Å; V558-F644 HydrophobicContact CG1-CE1 4.45Å; V558-F644 CarbonylContact O-C 3.6Å; V558-F644 VanDerWaalsContact O-CA 3.28Å; V558-F644 WeakPolarHBondContact O-CA 3.41Å; V558-Q645 PolarHBondContact O-N 3.01Å
559S71.6Confident71Confident76 Ų7691 Ų9153%0.53147%0.468SS..EExtended strand (participates in β ladder)trans-77.7128.6172.5-640000109.9P557 Q645P557-S559 PolarHBondContact O-N 3.39Å; S559-Q645 PolarHBondContact OG-NE2 3.22Å
560I70.8Confident71.6Confident27 Ų2789.6 Ų89.614%0.13847%0.472CS..PPolyproline II helixtrans-70.6131.1175.1-57.5165.5000108.5S562 V586 F644 T646I560-S562 PolarHBondContact O-N 3.07Å; I560-V586 HydrophobicContact CD1-CG1 3.4Å; I560-V586 HydrophobicContact CG1-CG1 4.08Å; I560-F644 HydrophobicContact CG1-CB 4.46Å; I560-T646 HydrophobicContact CD1-CG2 3.46Å; I560-T646 VanDerWaalsContact CD1-CG2 3.46Å
561P59.7Low72.4Confident90 Ų9089.2 Ų89.258%0.58446%0.461SS*.SBendtrans-75.769.7177.632.2-36000111.8Q503Q503-P561 HydrophobicContact CB-CG 3.81Å; Q503-P561 HydrophobicContact CG-CG 4.48Å
562S63.3Low73.3Confident28 Ų2886.2 Ų86.220%0.19646%0.456CS..  trans-130.1132.4172.8169.60000110.2I560 E564 H565 S566I560-S562 PolarHBondContact O-N 3.07Å; S562-E564 VanDerWaalsContact C-N 3.25Å; S562-E564 PolarHBondContact O-N 3.17Å; S562-H565 VanDerWaalsContact CB-ND1 3.32Å; S562-H565 WeakPolarHBondContact CB-ND1 3.27Å; S562-H565 PolarHBondContact O-N 3.16Å; S562-H565 PolarHBondContact OG-ND1 2.8Å; S562-S566 PolarHBondContact O-N 3.29Å
563P56.4Low74Confident110 Ų11085.6 Ų85.671%0.71445%0.45SS*.THydrogen-bonded Turntrans-56.7-38.4178.6-26.234.9000113.1S566P563-S566 PolarHBondContact O-OG 2.84Å
564E60.4Low75Confident118 Ų11880.7 Ų80.755%0.55143%0.432SS*.THydrogen-bonded Turntrans-68.2-48-179-56.4-160.6132.900112.1S562 S566 R567S562-E564 VanDerWaalsContact C-N 3.25Å; S562-E564 PolarHBondContact O-N 3.17Å; E564-S566 PolarHBondContact O-N 2.91Å; E564-R567 WeakPolarHBondContact O-CB 3.36Å; E564-R567 PolarHBondContact O-N 3.06Å
565H63.8Low75.6Confident22 Ų2281 Ų8110%0.10244%0.439CS..THydrogen-bonded Turntrans-65.4-20.4-177.5-67.572.9000113S562 T646S562-H565 VanDerWaalsContact CB-ND1 3.32Å; S562-H565 WeakPolarHBondContact CB-ND1 3.27Å; S562-H565 PolarHBondContact O-N 3.16Å; S562-H565 PolarHBondContact OG-ND1 2.8Å; H565-T646 WeakPolarHBondContact CA-O 3.12Å; H565-T646 WeakPolarHBondContact CB-O 3.47Å; H565-T646 PolarHBondContact CD2-O 3.19Å
566S63.3Low76.8Confident77 Ų7776.6 Ų76.654%0.53843%0.426SS..THydrogen-bonded Turntrans-83.2-17.9174.676.80000114.3S562 P563 E564S562-S566 PolarHBondContact O-N 3.29Å; P563-S566 PolarHBondContact O-OG 2.84Å; E564-S566 PolarHBondContact O-N 2.91Å
567R77.4Confident77.6Confident182 Ų18270.8 Ų70.869%0.68741%0.408SS*.SBendtrans-82.4128.5-167.8-173.3176.7-179.9177.71111.6E564 R569E564-R567 WeakPolarHBondContact O-CB 3.36Å; E564-R567 PolarHBondContact O-N 3.06Å; R567-R569 PolarHBondContact O-N 2.95Å
568L85.3Confident78.5Confident76 Ų7671.9 Ų71.940%0.39841%0.41SS..EExtended strand (participates in β ladder)trans-69.9118.6167.8-171.466.3000109.7R648 Q650L568-R648 WeakPolarHBondContact CA-O 3.45Å; L568-R648 HydrophobicContact CD1-CB 4.05Å; L568-Q650 HydrophobicContact CD1-CB 4.14Å; L568-Q650 HydrophobicContact CD2-CB 4.16Å; L568-Q650 HydrophobicContact CG-CB 4.16Å
569R90.1Very high79.1Confident85 Ų8570.5 Ų70.532%0.32140%0.401SS..EExtended strand (participates in β ladder)trans-97.1116.5177.4-56.7-178.1-167.4-112.78.3109.6R567 E647 R648 Y649 Q650R567-R569 PolarHBondContact O-N 2.95Å; R569-E647 IonicContact CZ-OE1 3.68Å; R569-E647 IonicContact CZ-OE2 2.86Å; R569-E647 IonicContact NE-OE1 2.7Å; R569-E647 IonicContact NE-OE2 3.18Å; R569-E647 PolarHBondContact NE-OE2 2.75Å; R569-E647 VanDerWaalsContact NH2-CD 3.33Å; R569-E647 IonicContact NH2-OE1 3.54Å; R569-E647 PolarHBondContact NH2-OE1 2.9Å; R569-E647 IonicContact NH2-OE2 3.37Å; R569-E647 PolarHBondContact NH2-OE2 2.69Å; R569-R648 PolarHBondContact N-O 2.84Å; R569-Y649 HydrophobicContact CB-CD1 3.68Å; R569-Y649 HydrophobicContact CB-CE1 3.91Å; R569-Y649 HydrophobicContact CG-CD1 4.47Å; R569-Y649 HydrophobicContact CG-CE1 4.29Å; R569-Y649 CarbonylContact O-C 3.6Å; R569-Y649 VanDerWaalsContact O-CA 3.23Å; R569-Y649 WeakPolarHBondContact O-CA 3.41Å; R569-Q650 PolarHBondContact O-N 3.11Å
570N92.1Very high80.1Confident132 Ų13270.6 Ų70.671%0.70640%0.398SS*.EExtended strand (participates in β ladder)trans-80133.4175.7-65.5-5.1000109.9Q650N570-Q650 WeakPolarHBondContact CA-O 3.36Å
571V91.6Very high81.2Confident39 Ų3969.3 Ų69.324%0.23639%0.392CS..EExtended strand (participates in β ladder)trans-132.9126.2-178.8-176.60000109.4V573 L581 Y649 Q650 V651 A652V571-V573 HydrophobicContact CG1-CG2 3.9Å; V571-L581 HydrophobicContact CG1-CD2 4.35Å; V571-L581 HydrophobicContact CG2-CD2 4.13Å; V571-Y649 HydrophobicContact CG2-CD1 3.71Å; V571-Y649 HydrophobicContact CG2-CE1 4.44Å; V571-Q650 PolarHBondContact N-O 2.89Å; V571-V651 CarbonylContact O-C 3.48Å; V571-V651 WeakPolarHBondContact O-CA 3.28Å; V571-A652 PolarHBondContact O-N 3.3Å
572T91.1Very high82.8Confident99 Ų9968.1 Ų68.161%0.60738%0.384SS*.EExtended strand (participates in β ladder)trans-108.9123.8174.648.50000110A652T572-A652 WeakPolarHBondContact CA-O 3.49Å; T572-A652 HydrophobicContact CG2-CB 4.46Å
573V89.8Confident84Confident14 Ų1466.9 Ų66.99%0.08538%0.376CS..EExtended strand (participates in β ladder)trans-122.2140.6-178.6-170.30000109.3V571 M579 A625 A652 V653 V654V571-V573 HydrophobicContact CG1-CG2 3.9Å; V573-M579 HydrophobicContact CG1-CB 4.37Å; V573-M579 HydrophobicContact CG2-CB 4.17Å; V573-M579 HydrophobicContact CG2-CG 3.96Å; V573-M579 HydrophobicContact CG2-SD 4Å; V573-A625 HydrophobicContact CB-CB 4.5Å; V573-A625 HydrophobicContact CG1-CB 3.77Å; V573-A652 PolarHBondContact N-O 2.82Å; V573-V653 CarbonylContact O-C 3.59Å; V573-V653 VanDerWaalsContact O-CA 3.3Å; V573-V653 WeakPolarHBondContact O-CA 3.44Å; V573-V654 WeakPolarHBondContact O-CG2 3.29Å; V573-V654 PolarHBondContact O-N 2.71Å
574V89.6Confident85.5Confident45 Ų4566 Ų6627%0.27336%0.362SS..EExtended strand (participates in β ladder)trans-83.8143175.7-1750000109.7G576 S577 V654 A657V574-G576 PolarHBondContact O-N 2.94Å; V574-S577 VanDerWaalsContact O-CB 3.27Å; V574-S577 WeakPolarHBondContact O-CB 3.48Å; V574-S577 PolarHBondContact O-N 2.99Å; V574-S577 PolarHBondContact O-OG 3.39Å; V574-V654 CarbonylContact C-O 3.53Å; V574-V654 WeakPolarHBondContact CA-O 3.45Å; V574-V654 HydrophobicContact CG2-CG2 4.42Å; V574-A657 HydrophobicContact CG2-CB 3.97Å
575V89.9Confident86.9Confident69 Ų6962.3 Ų62.342%0.41835%0.345SS..THydrogen-bonded Turntrans-52131.2177.9169.40000111S577 A625 Q627 V653 V654V575-S577 VanDerWaalsContact C-N 3.31Å; V575-S577 PolarHBondContact O-N 3.23Å; V575-A625 CarbonylContact C-O 3.55Å; V575-A625 VanDerWaalsContact CA-O 3.25Å; V575-A625 WeakPolarHBondContact CA-O 3.26Å; V575-Q627 HydrophobicContact CG2-CG 4.48Å; V575-V653 HydrophobicContact CG2-CG1 3.73Å; V575-V654 PolarHBondContact N-O 3.42Å
576G85Confident88.1Confident46 Ų4662.5 Ų62.547%0.47435%0.348SS..THydrogen-bonded Turntrans80.42.2-178.700000115.2V574 A625V574-G576 PolarHBondContact O-N 2.94Å; G576-A625 PolarHBondContact N-O 2.77Å
577S89.3Confident89.5Confident53 Ų5359 Ų5937%0.37132%0.323SS..SBendtrans-89.2144.6171.8-55.60000111.6V574 V575 M579 A625V574-S577 VanDerWaalsContact O-CB 3.27Å; V574-S577 WeakPolarHBondContact O-CB 3.48Å; V574-S577 PolarHBondContact O-N 2.99Å; V574-S577 PolarHBondContact O-OG 3.39Å; V575-S577 VanDerWaalsContact C-N 3.31Å; V575-S577 PolarHBondContact O-N 3.23Å; S577-M579 PolarHBondContact O-N 2.82Å; S577-A625 WeakPolarHBondContact O-CB 3.46Å; S577-A625 PolarHBondContact O-N 3.24Å
578D89.7Confident90.3Very high90 Ų9053 Ų5348%0.48131%0.305SS..PPolyproline II helixtrans-67.9126.9172.9-81.419.6000111.2P623 E624D578-P623 VanDerWaalsContact OD1-CA 3.22Å; D578-P623 WeakPolarHBondContact OD1-CA 3.12Å; D578-E624 PolarHBondContact OD1-N 3.25Å; D578-E624 VanDerWaalsContact OD1-N 3.13Å
579M90.8Very high90.6Very high2 Ų253.1 Ų53.11%0.0131%0.306CS..EExtended strand (participates in β ladder)trans-93.6127.8175.4179172.56200111V573 S577 L581 I621 V622 A625 Y633 V651V573-M579 HydrophobicContact CG1-CB 4.37Å; V573-M579 HydrophobicContact CG2-CB 4.17Å; V573-M579 HydrophobicContact CG2-CG 3.96Å; V573-M579 HydrophobicContact CG2-SD 4Å; S577-M579 PolarHBondContact O-N 2.82Å; M579-L581 HydrophobicContact CE-CD1 4Å; M579-L581 HydrophobicContact CE-CG 4.31Å; M579-L581 HydrophobicContact CG-CD2 3.92Å; M579-L581 HydrophobicContact CG-CG 3.91Å; M579-L581 HydrophobicContact SD-CD1 3.99Å; M579-L581 HydrophobicContact SD-CD2 3.91Å; M579-L581 HydrophobicContact SD-CG 3.94Å; M579-I621 WeakPolarHBondContact O-CA 3.29Å; M579-V622 HydrophobicContact CB-CB 4.33Å; M579-V622 HydrophobicContact CE-CB 3.93Å; M579-V622 HydrophobicContact CE-CG2 3.64Å; M579-V622 PolarHBondContact N-O 2.99Å; M579-V622 PolarHBondContact O-N 3.45Å; M579-A625 HydrophobicContact CB-CB 4.45Å; M579-Y633 HydrophobicContact CE-CE1 3.86Å; M579-Y633 HydrophobicContact CE-CE2 4.3Å; M579-V651 HydrophobicContact CE-CG1 4.36Å; M579-V651 HydrophobicContact CE-CG2 4.38Å; M579-V651 HydrophobicContact SD-CB 4.24Å; M579-V651 HydrophobicContact SD-CG1 3.52Å; M579-V651 VanDerWaalsContact SD-CG1 3.52Å; M579-V651 HydrophobicContact SD-CG2 3.64Å
580V93.1Very high90.7Very high78 Ų7849.6 Ų49.647%0.47330%0.295SS..EExtended strand (participates in β ladder)trans-114.9111.4175.5-177.30000109.5A619 L620 I621V580-A619 HydrophobicContact CG1-CB 3.79Å; V580-L620 WeakPolarHBondContact CA-O 3.32Å; V580-I621 HydrophobicContact CB-CD1 4.33Å; V580-I621 HydrophobicContact CG1-CD1 3.89Å; V580-I621 HydrophobicContact CG2-CD1 3.89Å
581L93.4Very high90.7Very high1 Ų149.2 Ų49.21%0.00529%0.289CS..EExtended strand (participates in β ladder)trans-112.1105.6175.2-57.3-175.8000109.8V571 M579 W594 A619 L620 Y633 Y649 V651V571-L581 HydrophobicContact CG1-CD2 4.35Å; V571-L581 HydrophobicContact CG2-CD2 4.13Å; M579-L581 HydrophobicContact CE-CD1 4Å; M579-L581 HydrophobicContact CE-CG 4.31Å; M579-L581 HydrophobicContact CG-CD2 3.92Å; M579-L581 HydrophobicContact CG-CG 3.91Å; M579-L581 HydrophobicContact SD-CD1 3.99Å; M579-L581 HydrophobicContact SD-CD2 3.91Å; M579-L581 HydrophobicContact SD-CG 3.94Å; L581-W594 HydrophobicContact CB-CH2 3.75Å; L581-W594 HydrophobicContact CB-CZ3 4.28Å; L581-W594 HydrophobicContact CD1-CZ3 4.26Å; L581-A619 CarbonylContact O-C 3.47Å; L581-A619 WeakPolarHBondContact O-CA 3.04Å; L581-L620 HydrophobicContact CB-CB 4.42Å; L581-L620 PolarHBondContact N-O 2.91Å; L581-L620 PolarHBondContact O-N 3.08Å; L581-Y633 HydrophobicContact CD1-CD1 3.49Å; L581-Y633 VanDerWaalsContact CD1-CD1 3.49Å; L581-Y633 HydrophobicContact CD1-CD2 4.38Å; L581-Y633 HydrophobicContact CD1-CE1 4.1Å; L581-Y633 HydrophobicContact CD1-CG 3.68Å; L581-Y649 HydrophobicContact CB-CD2 4.22Å; L581-Y649 HydrophobicContact CB-CE2 4.1Å; L581-Y649 HydrophobicContact CD1-CD2 4.2Å; L581-Y649 HydrophobicContact CD1-CG 4.25Å; L581-Y649 HydrophobicContact CD2-CD1 3.88Å; L581-Y649 HydrophobicContact CD2-CD2 4.45Å; L581-Y649 HydrophobicContact CD2-CE1 4.26Å; L581-Y649 HydrophobicContact CD2-CG 4Å; L581-V651 HydrophobicContact CD1-CG2 4.06Å; L581-V651 HydrophobicContact CD2-CG2 4.38Å
582P92.8Very high90.7Very high65 Ų6548.5 Ų48.542%0.42229%0.285SS..EExtended strand (participates in β ladder)trans-54.7156174-27.335.6000113.4Y649P582-Y649 WeakPolarHBondContact O-CE2 3.44Å; P582-Y649 PolarHBondContact O-OH 3.02Å
583C90.3Very high90.7Very high2 Ų245.2 Ų45.21%0.01426%0.262CS..  trans-151.1117.3166.3173.90000110.9W594 F613 K618 C635 T646C583-W594 HydrophobicContact CB-CH2 4.14Å; C583-W594 HydrophobicContact CB-CZ2 3.52Å; C583-F613 HydrophobicContact CB-CE2 4.17Å; C583-K618 PolarHBondContact N-O 3.47Å; C583-C635 HydrophobicContact CB-CB 3.63Å; C583-C635 WeakPolarHBondContact CB-SG 3.41Å; C583-C635 WeakPolarHBondContact SG-CB 3.35Å; C583-C635 CovalentContact SG-SG 2.02Å; C583-C635 PolarHBondContact SG-SG 3.44Å; C583-T646 PolarHBondContact SG-OG1 2.87Å
584Q87.6Confident90.9Very high92 Ų9244.6 Ų44.643%0.4326%0.259SS..  trans-72.9130.2171.2-53.3-164.337.300108.9T646Q584-T646 WeakPolarHBondContact O-CB 3.49Å; Q584-T646 WeakPolarHBondContact O-CG2 3.42Å; Q584-T646 PolarHBondContact O-OG1 2.87Å
585L89.6Confident91.1Very high39 Ų3943.3 Ų43.320%0.20425%0.251CS..  trans-101.6138.2174.4-59.6177.5000108.8S587 P592 F613 S637L585-S587 PolarHBondContact O-N 2.82Å; L585-P592 HydrophobicContact CD2-CB 4.3Å; L585-F613 HydrophobicContact CD1-CE1 4.34Å; L585-F613 HydrophobicContact CD1-CZ 4.25Å; L585-S637 WeakPolarHBondContact CA-OG 3.43Å
586V89.3Confident91.2Very high27 Ų2741.1 Ų41.116%0.16424%0.237CC..SBendtrans-72.8-15.7-175.1-59.10000113.8K29 I560 S637 F644 T646K29-V586 VanDerWaalsContact CE-O 3.29Å; K29-V586 WeakPolarHBondContact CE-O 3.45Å; I560-V586 HydrophobicContact CD1-CG1 3.4Å; I560-V586 HydrophobicContact CG1-CG1 4.08Å; V586-S637 PolarHBondContact N-OG 2.98Å; V586-S637 VanDerWaalsContact N-OG 3.09Å; V586-F644 HydrophobicContact CG1-CB 3.89Å; V586-F644 HydrophobicContact CG1-CG 4.11Å; V586-F644 HydrophobicContact CG2-CB 4.38Å; V586-F644 HydrophobicContact CG2-CD2 3.55Å; V586-F644 HydrophobicContact CG2-CE2 3.83Å; V586-F644 HydrophobicContact CG2-CG 3.94Å; V586-F644 HydrophobicContact CG2-CZ 4.43Å; V586-T646 HydrophobicContact CG1-CG2 4.28Å
587S92.4Very high91.4Very high2 Ų242.9 Ų42.91%0.01424%0.236CC..SBendtrans-149.8142.6-174.5161.90000108.3R28 L585 L589 A590 E639R28-S587 WeakPolarHBondContact CG-OG 3.29Å; R28-S587 CarbonylContact O-C 3.59Å; R28-S587 VanDerWaalsContact O-CA 3.31Å; R28-S587 WeakPolarHBondContact O-CA 3.49Å; R28-S587 PolarHBondContact O-OG 3.18Å; L585-S587 PolarHBondContact O-N 2.82Å; S587-L589 PolarHBondContact O-N 3.01Å; S587-L589 WeakPolarHBondContact OG-CB 3.38Å; S587-L589 PolarHBondContact OG-N 2.89Å; S587-A590 WeakPolarHBondContact O-CB 3.47Å; S587-A590 PolarHBondContact O-N 2.87Å; S587-E639 VanDerWaalsContact CB-OE1 3.3Å; S587-E639 WeakPolarHBondContact CB-OE1 3.01Å; S587-E639 WeakPolarHBondContact CB-OE2 3.27Å; S587-E639 VanDerWaalsContact OG-CD 3.31Å; S587-E639 PolarHBondContact OG-OE1 3.27Å
588N93.4Very high91.3Very high57 Ų5745.5 Ų45.531%0.30525%0.246SC..THydrogen-bonded Turntrans-70.3-12.6172.3-61.7-42.1000112.5V26 P27 R28 T30V26-N588 HydrophobicContact CG1-CB 3.66Å; P27-N588 WeakPolarHBondContact O-CB 3.34Å; P27-N588 PolarHBondContact O-ND2 3.38Å; R28-N588 PolarHBondContact O-N 2.81Å; T30-N588 PolarHBondContact OG1-ND2 2.84Å
589L92.9Very high91.4Very high79 Ų7950.8 Ų50.841%0.41426%0.259SS..THydrogen-bonded Turntrans-90.8-10.4173-57.8177.9000112.7V26 R28 S587V26-L589 HydrophobicContact CB-CD2 3.91Å; V26-L589 HydrophobicContact CG1-CD2 4.36Å; R28-L589 HydrophobicContact CB-CD1 3.98Å; R28-L589 HydrophobicContact CB-CG 4.38Å; R28-L589 HydrophobicContact CG-CD1 4.03Å; R28-L589 HydrophobicContact CG-CG 4.37Å; S587-L589 PolarHBondContact O-N 3.01Å; S587-L589 WeakPolarHBondContact OG-CB 3.38Å; S587-L589 PolarHBondContact OG-N 2.89Å
590A92.3Very high91.4Very high10 Ų1055.8 Ų55.88%0.08328%0.282CS..  trans-77.2155.6179.300000112.3S587 S637 E638 E639S587-A590 WeakPolarHBondContact O-CB 3.47Å; S587-A590 PolarHBondContact O-N 2.87Å; A590-S637 WeakPolarHBondContact CB-OG 3.11Å; A590-E638 CarbonylContact C-O 3.5Å; A590-E638 VanDerWaalsContact CA-O 3.23Å; A590-E638 WeakPolarHBondContact CA-O 3.49Å; A590-E638 WeakPolarHBondContact CB-O 3.45Å; A590-E639 HydrophobicContact CB-CB 4.04Å
591Q91.5Very high91.2Very high125 Ų12553.7 Ų53.758%0.58427%0.268SS*.EExtended strand (participates in β ladder)trans-107.7151.9174.1-60.3-168.116.400110.9E638Q591-E638 PolarHBondContact N-O 3.38Å; Q591-E638 PolarHBondContact O-N 2.8Å
592P91.7Very high90.7Very high24 Ų2460 Ų6016%0.15630%0.298CS..EExtended strand (participates in β ladder)trans-77.8126.7174.132.6-35.2000110.5L585 L603 F613L585-P592 HydrophobicContact CD2-CB 4.3Å; P592-L603 HydrophobicContact CG-CD1 4.17Å; P592-F613 HydrophobicContact CB-CB 4.46Å; P592-F613 HydrophobicContact CB-CD1 4.25Å; P592-F613 HydrophobicContact CB-CD2 3.72Å; P592-F613 HydrophobicContact CB-CE1 4.38Å; P592-F613 HydrophobicContact CB-CE2 3.88Å; P592-F613 HydrophobicContact CB-CG 3.9Å; P592-F613 HydrophobicContact CB-CZ 4.2Å; P592-F613 HydrophobicContact CG-CB 3.81Å; P592-F613 HydrophobicContact CG-CD1 3.65Å; P592-F613 HydrophobicContact CG-CD2 3.89Å; P592-F613 HydrophobicContact CG-CE1 4.1Å; P592-F613 HydrophobicContact CG-CE2 4.33Å; P592-F613 HydrophobicContact CG-CG 3.5Å; P592-F613 HydrophobicContact CG-CZ 4.41Å
593F91.7Very high90.2Very high30 Ų3059.9 Ų59.913%0.13229%0.293CS..EExtended strand (participates in β ladder)trans-119.9115.7173.3-179.3-91.4000109V595 E600 Y636 E638 K643F593-V595 HydrophobicContact CD1-CG2 4.19Å; F593-V595 HydrophobicContact CE1-CG2 3.57Å; F593-V595 HydrophobicContact CZ-CG2 4.42Å; F593-E600 HydrophobicContact CE2-CG 3.61Å; F593-E600 VanDerWaalsContact CE2-OE2 3.24Å; F593-E600 WeakPolarHBondContact CE2-OE2 3.47Å; F593-E600 HydrophobicContact CZ-CB 4.22Å; F593-E600 HydrophobicContact CZ-CG 3.6Å; F593-E600 VanDerWaalsContact CZ-OE2 3.22Å; F593-E600 WeakPolarHBondContact CZ-OE2 3.42Å; F593-Y636 AromaticContact CD1-CD2 3.89Å; F593-Y636 HydrophobicContact CD1-CD2 3.89Å; F593-Y636 HydrophobicContact CD1-CG 4.37Å; F593-Y636 HydrophobicContact CE1-CD2 4.48Å; F593-Y636 PolarHBondContact N-O 3.11Å; F593-Y636 PolarHBondContact O-N 3.22Å; F593-E638 HydrophobicContact CB-CB 4.29Å; F593-K643 HydrophobicContact CD1-CD 3.81Å; F593-K643 HydrophobicContact CE1-CD 4.03Å; F593-K643 VanDerWaalsContact CE1-NZ 3.33Å; F593-K643 HydrophobicContact CG-CD 4.21Å
594W93.1Very high89.2Confident1 Ų161.4 Ų61.40%0.00431%0.309CS..EExtended strand (participates in β ladder)trans-108.7140.5-173.4-76.289.1000112.4L581 C583 L601 F613 L620 Y633 C635 Y649L581-W594 HydrophobicContact CB-CH2 3.75Å; L581-W594 HydrophobicContact CB-CZ3 4.28Å; L581-W594 HydrophobicContact CD1-CZ3 4.26Å; C583-W594 HydrophobicContact CB-CH2 4.14Å; C583-W594 HydrophobicContact CB-CZ2 3.52Å; W594-L601 HydrophobicContact CB-CB 3.98Å; W594-L601 HydrophobicContact CB-CD2 4.07Å; W594-L601 PolarHBondContact O-N 2.69Å; W594-F613 AromaticContact NE1-CD2 3.87Å; W594-L620 HydrophobicContact CD2-CB 4.19Å; W594-L620 HydrophobicContact CD2-CD2 3.8Å; W594-L620 HydrophobicContact CE3-CD2 3.91Å; W594-L620 HydrophobicContact CG-CD2 4.21Å; W594-L620 HydrophobicContact CH2-CB 4.02Å; W594-L620 HydrophobicContact CH2-CD2 4.43Å; W594-L620 HydrophobicContact CZ2-CB 3.43Å; W594-L620 VanDerWaalsContact CZ2-CB 3.43Å; W594-L620 HydrophobicContact CZ2-CD2 4.36Å; W594-L620 HydrophobicContact CZ3-CD2 4.23Å; W594-Y633 HydrophobicContact CE3-CD1 4.31Å; W594-Y633 HydrophobicContact CZ3-CD1 4.44Å; W594-C635 HydrophobicContact CD2-CB 3.97Å; W594-C635 VanDerWaalsContact CE2-SG 3.54Å; W594-C635 HydrophobicContact CE3-CB 3.94Å; W594-C635 HydrophobicContact CH2-CB 3.73Å; W594-C635 HydrophobicContact CZ2-CB 3.74Å; W594-C635 HydrophobicContact CZ3-CB 3.82Å; W594-Y649 HydrophobicContact CH2-CD2 4.32Å; W594-Y649 HydrophobicContact CH2-CE2 4.04Å; W594-Y649 HydrophobicContact CZ3-CD2 4.17Å; W594-Y649 HydrophobicContact CZ3-CE2 4.33Å
595V92.8Very high88Confident18 Ų1863.2 Ų63.211%0.10932%0.322CS..EExtended strand (participates in β ladder)trans-124.8129.7175.6176.20000109.3F593 R599 Y633 I634 Y636F593-V595 HydrophobicContact CD1-CG2 4.19Å; F593-V595 HydrophobicContact CE1-CG2 3.57Å; F593-V595 HydrophobicContact CZ-CG2 4.42Å; V595-R599 CarbonylContact C-O 3.46Å; V595-R599 VanDerWaalsContact CA-O 3.28Å; V595-R599 WeakPolarHBondContact CA-O 3.38Å; V595-R599 WeakPolarHBondContact CG1-O 3.33Å; V595-Y633 CarbonylContact O-C 3.45Å; V595-Y633 WeakPolarHBondContact O-CA 3.48Å; V595-I634 PolarHBondContact N-O 2.81Å; V595-I634 PolarHBondContact O-N 2.72Å; V595-Y636 HydrophobicContact CB-CE2 4.08Å; V595-Y636 HydrophobicContact CG2-CD2 4.12Å; V595-Y636 HydrophobicContact CG2-CE2 3.65Å
596V92Very high86.7Confident22 Ų2265.8 Ų65.813%0.13334%0.341CS..EExtended strand (participates in β ladder)trans-123.6121.7178.9-178.40000108.9D598 R599 L601 R632 Y633V596-D598 PolarHBondContact O-N 3.41Å; V596-R599 PolarHBondContact N-O 3.38Å; V596-R599 PolarHBondContact O-N 2.85Å; V596-L601 HydrophobicContact CG2-CB 4.02Å; V596-L601 HydrophobicContact CG2-CD1 4.3Å; V596-L601 HydrophobicContact CG2-CD2 4.02Å; V596-L601 HydrophobicContact CG2-CG 4.35Å; V596-R632 WeakPolarHBondContact CA-O 3.33Å; V596-Y633 HydrophobicContact CG1-CD2 4.13Å; V596-Y633 HydrophobicContact CG1-CE1 4.36Å; V596-Y633 HydrophobicContact CG1-CE2 3.7Å; V596-Y633 HydrophobicContact CG2-CD1 3.45Å; V596-Y633 VanDerWaalsContact CG2-CD1 3.45Å; V596-Y633 HydrophobicContact CG2-CD2 4.22Å; V596-Y633 HydrophobicContact CG2-CE1 3.35Å; V596-Y633 HydrophobicContact CG2-CE2 4.12Å; V596-Y633 HydrophobicContact CG2-CG 3.87Å
597N90.5Very high85.4Confident84 Ų8474 Ų7445%0.44938%0.377SS..THydrogen-bonded Turntrans48.444.2-177.9-61.6-32.9000112.4R599 A630 G631 R632N597-R599 PolarHBondContact O-N 3.49Å; N597-A630 PolarHBondContact ND2-O 2.95Å; N597-G631 WeakPolarHBondContact OD1-CA 3.41Å; N597-R632 PolarHBondContact N-O 3.03Å; N597-R632 PolarHBondContact OD1-N 3.07Å
598D87.4Confident84.1Confident108 Ų10877.6 Ų77.658%0.57841%0.407SS*.THydrogen-bonded Turntrans60.923.3-179.3-55.6-29.2000115.6V596 R632V596-D598 PolarHBondContact O-N 3.41Å; D598-R632 IonicContact OD1-CZ 3.66Å; D598-R632 IonicContact OD1-NE 3.93Å; D598-R632 IonicContact OD1-NH2 2.66Å; D598-R632 PolarHBondContact OD1-NH2 3.41Å; D598-R632 IonicContact OD2-CZ 3.8Å; D598-R632 IonicContact OD2-NH2 2.75Å; D598-R632 PolarHBondContact OD2-NH2 2.81Å
599R90.4Very high82.9Confident201 Ų20177.4 Ų77.476%0.75842%0.419SS*.EExtended strand (participates in β ladder)trans-117.8147.5167.7-60.7-176.8179.5-165.4-1.7111.1V595 V596 N597V595-R599 CarbonylContact C-O 3.46Å; V595-R599 VanDerWaalsContact CA-O 3.28Å; V595-R599 WeakPolarHBondContact CA-O 3.38Å; V595-R599 WeakPolarHBondContact CG1-O 3.33Å; V596-R599 PolarHBondContact N-O 3.38Å; V596-R599 PolarHBondContact O-N 2.85Å; N597-R599 PolarHBondContact O-N 3.49Å
600E90.8Very high82.4Confident107 Ų10774.5 Ų74.550%0.541%0.408SS..EExtended strand (participates in β ladder)trans-66.4129.8175.5-174.9173.6135.100111.4F593 Q602F593-E600 HydrophobicContact CE2-CG 3.61Å; F593-E600 VanDerWaalsContact CE2-OE2 3.24Å; F593-E600 WeakPolarHBondContact CE2-OE2 3.47Å; F593-E600 HydrophobicContact CZ-CB 4.22Å; F593-E600 HydrophobicContact CZ-CG 3.6Å; F593-E600 VanDerWaalsContact CZ-OE2 3.22Å; F593-E600 WeakPolarHBondContact CZ-OE2 3.42Å; E600-Q602 PolarHBondContact OE1-NE2 3Å
601L88.7Confident82.1Confident34 Ų3475.8 Ų75.818%0.17842%0.416CS..  trans-89.7105.7174.3-177.968.9000109.2W594 V596 L603 P611 L620 Y633W594-L601 HydrophobicContact CB-CB 3.98Å; W594-L601 HydrophobicContact CB-CD2 4.07Å; W594-L601 PolarHBondContact O-N 2.69Å; V596-L601 HydrophobicContact CG2-CB 4.02Å; V596-L601 HydrophobicContact CG2-CD1 4.3Å; V596-L601 HydrophobicContact CG2-CD2 4.02Å; V596-L601 HydrophobicContact CG2-CG 4.35Å; L601-L603 HydrophobicContact CD2-CD2 4.31Å; L601-L603 PolarHBondContact O-N 3.19Å; L601-P611 HydrophobicContact CD1-CB 4.39Å; L601-P611 HydrophobicContact CD1-CG 4.17Å; L601-P611 HydrophobicContact CD2-CB 4.19Å; L601-P611 HydrophobicContact CG-CB 4.45Å; L601-L620 HydrophobicContact CD2-CD1 4.04Å; L601-L620 HydrophobicContact CD2-CD2 3.66Å; L601-Y633 HydrophobicContact CD2-CE1 4.43Å
602Q84.3Confident82Confident133 Ų13373.5 Ų73.562%0.62140%0.402SS*.PPolyproline II helixtrans-64.5120.7170.5-61.4-55.3-45.400109.4E600E600-Q602 PolarHBondContact OE1-NE2 3Å
603L81.9Confident81.9Confident63 Ų6374 Ų7433%0.3340%0.401SS..PPolyproline II helixtrans-82.8125.5175.2-58.8178.4000108.6P592 L601 P611 F613 L620P592-L603 HydrophobicContact CG-CD1 4.17Å; L601-L603 HydrophobicContact CD2-CD2 4.31Å; L601-L603 PolarHBondContact O-N 3.19Å; L603-P611 CarbonylContact C-O 3.04Å; L603-P611 WeakPolarHBondContact CA-O 3.41Å; L603-F613 HydrophobicContact CD1-CB 4.06Å; L603-L620 HydrophobicContact CD2-CD1 3.56Å
604G69.1Low81.8Confident34 Ų3474.9 Ų74.935%0.35141%0.408SS..PPolyproline II helixtrans-86.3163.7-178.200000113.4P611G604-P611 PolarHBondContact N-O 3.06Å
605D63.3Low81.4Confident129 Ų12984.1 Ų84.169%0.6944%0.443SS*.PPolyproline II helixtrans-64.2148.1170.1-110.7-42.4000111.1E607 A608D605-E607 PolarHBondContact O-N 2.92Å; D605-E607 VanDerWaalsContact O-N 3.13Å; D605-A608 WeakPolarHBondContact O-CB 3.36Å; D605-A608 PolarHBondContact O-N 2.98Å
606P60.7Low81Confident93 Ų9389.6 Ų89.660%0.60448%0.476SS*.G310 helixtrans-58-31-175.2-2635.4000114.5A608P606-A608 VanDerWaalsContact C-N 3.34Å
607E61.8Low80.8Confident199 Ų19993.9 Ų93.993%0.9350%0.498SS*.G310 helixtrans-78.5-16-179.1-58.4-173.4168.200113.2D605 G609D605-E607 PolarHBondContact O-N 2.92Å; D605-E607 VanDerWaalsContact O-N 3.13Å; E607-G609 VanDerWaalsContact C-N 3.31Å; E607-G609 PolarHBondContact O-N 2.99Å
608A65.3Low80.7Confident78 Ų7894.4 Ų94.465%0.64550%0.496SS*.G310 helixtrans-85.73.8-174.500000114.3D605 P606 G610D605-A608 WeakPolarHBondContact O-CB 3.36Å; D605-A608 PolarHBondContact O-N 2.98Å; P606-A608 VanDerWaalsContact C-N 3.34Å; A608-G610 PolarHBondContact O-N 2.96Å; A608-G610 VanDerWaalsContact O-N 3.12Å
609G69.8Low80.9Confident54 Ų5489.3 Ų89.356%0.55747%0.469SS*.THydrogen-bonded Turntrans6513179.500000115.1E607 P623E607-G609 VanDerWaalsContact C-N 3.31Å; E607-G609 PolarHBondContact O-N 2.99Å; G609-P623 WeakPolarHBondContact O-CG 3.18Å
610G81.3Confident81.1Confident18 Ų1879.8 Ų79.819%0.18643%0.433CS..SBendtrans-92.5-177.4-174.500000115.3A608 R612 P623A608-G610 PolarHBondContact O-N 2.96Å; A608-G610 VanDerWaalsContact O-N 3.12Å; G610-R612 PolarHBondContact O-N 2.8Å; G610-P623 WeakPolarHBondContact O-CD 3.3Å
611P86.8Confident81.1Confident36 Ų3675.1 Ų75.123%0.23441%0.411CS..  trans-59.3124.4169-16.328.5000110.6L601 L603 G604 L620 I621 V622L601-P611 HydrophobicContact CD1-CB 4.39Å; L601-P611 HydrophobicContact CD1-CG 4.17Å; L601-P611 HydrophobicContact CD2-CB 4.19Å; L601-P611 HydrophobicContact CG-CB 4.45Å; L603-P611 CarbonylContact C-O 3.04Å; L603-P611 WeakPolarHBondContact CA-O 3.41Å; G604-P611 PolarHBondContact N-O 3.06Å; P611-L620 HydrophobicContact CB-CD1 4.23Å; P611-I621 WeakPolarHBondContact CA-O 3.26Å; P611-V622 HydrophobicContact CB-CG1 4.33Å; P611-V622 HydrophobicContact CB-CG2 4.28Å; P611-V622 HydrophobicContact CG-CG1 4.16Å
612R89.8Confident81.2Confident78 Ų7873.6 Ų73.629%0.29440%0.404SS..EExtended strand (participates in β ladder)trans-135.6149.8-17664.9-178.4-175.6-85.1-0.1111.3G610 I621G610-R612 PolarHBondContact O-N 2.8Å; R612-I621 HydrophobicContact CG-CB 4.05Å; R612-I621 PolarHBondContact N-O 3.24Å; R612-I621 PolarHBondContact O-N 3.5Å
613F89.5Confident81.4Confident33 Ų3368.4 Ų68.415%0.14538%0.381CS..EExtended strand (participates in β ladder)trans-98.5117.4173.3-174.3-94.3000111.5C583 L585 P592 W594 L603 R615 K618 A619C583-F613 HydrophobicContact CB-CE2 4.17Å; L585-F613 HydrophobicContact CD1-CE1 4.34Å; L585-F613 HydrophobicContact CD1-CZ 4.25Å; P592-F613 HydrophobicContact CB-CB 4.46Å; P592-F613 HydrophobicContact CB-CD1 4.25Å; P592-F613 HydrophobicContact CB-CD2 3.72Å; P592-F613 HydrophobicContact CB-CE1 4.38Å; P592-F613 HydrophobicContact CB-CE2 3.88Å; P592-F613 HydrophobicContact CB-CG 3.9Å; P592-F613 HydrophobicContact CB-CZ 4.2Å; P592-F613 HydrophobicContact CG-CB 3.81Å; P592-F613 HydrophobicContact CG-CD1 3.65Å; P592-F613 HydrophobicContact CG-CD2 3.89Å; P592-F613 HydrophobicContact CG-CE1 4.1Å; P592-F613 HydrophobicContact CG-CE2 4.33Å; P592-F613 HydrophobicContact CG-CG 3.5Å; P592-F613 HydrophobicContact CG-CZ 4.41Å; W594-F613 AromaticContact NE1-CD2 3.87Å; L603-F613 HydrophobicContact CD1-CB 4.06Å; F613-R615 HydrophobicContact CD1-CG 4.15Å; F613-R615 HydrophobicContact CE1-CG 4.32Å; F613-K618 VanDerWaalsContact CZ-C 3.49Å; F613-K618 HydrophobicContact CZ-CB 4.31Å; F613-A619 CarbonylContact C-O 3.52Å; F613-A619 WeakPolarHBondContact CA-O 3.33Å; F613-A619 VanDerWaalsContact CD2-C 3.41Å; F613-A619 WeakPolarHBondContact CD2-O 3.26Å
614D88.3Confident81.6Confident50 Ų5072.6 Ų72.627%0.26740%0.399SS..EExtended strand (participates in β ladder)trans-82118.3172.1-170-62.7000110T616 L617 K618 A619 I621D614-T616 VanDerWaalsContact C-N 3.34Å; D614-T616 VanDerWaalsContact OD1-CA 3.31Å; D614-T616 WeakPolarHBondContact OD1-CA 3.44Å; D614-T616 VanDerWaalsContact OD1-CB 3.22Å; D614-T616 WeakPolarHBondContact OD1-CB 3.48Å; D614-T616 PolarHBondContact OD1-N 3.41Å; D614-L617 HydrophobicContact CB-CB 4.17Å; D614-L617 HydrophobicContact CB-CD1 4.31Å; D614-L617 HydrophobicContact CB-CG 4.42Å; D614-L617 PolarHBondContact OD1-N 3.24Å; D614-K618 WeakPolarHBondContact O-CA 3.46Å; D614-K618 PolarHBondContact O-N 3.2Å; D614-A619 PolarHBondContact N-O 2.99Å; D614-A619 PolarHBondContact O-N 3.25Å; D614-A619 VanDerWaalsContact O-N 3.08Å; D614-I621 HydrophobicContact CB-CD1 4.31Å; D614-I621 HydrophobicContact CB-CG1 3.94Å
615R84.3Confident82.4Confident195 Ų19571 Ų7174%0.73638%0.382SS*.THydrogen-bonded Turntrans-75.3-20.6-179.1-66.8-173.8177.8-160.2-0.4113.9F613F613-R615 HydrophobicContact CD1-CG 4.15Å; F613-R615 HydrophobicContact CE1-CG 4.32Å
616T85.1Confident83.5Confident132 Ų13266 Ų6681%0.8136%0.361SS*.THydrogen-bonded Turntrans-81.6-47.6-179.5-45.40000110.1D614 K618D614-T616 VanDerWaalsContact C-N 3.34Å; D614-T616 VanDerWaalsContact OD1-CA 3.31Å; D614-T616 WeakPolarHBondContact OD1-CA 3.44Å; D614-T616 VanDerWaalsContact OD1-CB 3.22Å; D614-T616 WeakPolarHBondContact OD1-CB 3.48Å; D614-T616 PolarHBondContact OD1-N 3.41Å; T616-K618 VanDerWaalsContact C-N 3.27Å
617L86.9Confident84.6Confident112 Ų11268.1 Ų68.159%0.58636%0.363SS*.THydrogen-bonded Turntrans-76.5-15.9173.5-59.5176.4000112.6D614 A619 I621D614-L617 HydrophobicContact CB-CB 4.17Å; D614-L617 HydrophobicContact CB-CD1 4.31Å; D614-L617 HydrophobicContact CB-CG 4.42Å; D614-L617 PolarHBondContact OD1-N 3.24Å; L617-A619 VanDerWaalsContact C-N 3.33Å; L617-A619 HydrophobicContact CB-CB 4.11Å; L617-A619 PolarHBondContact O-N 3.13Å; L617-I621 HydrophobicContact CD1-CD1 4.07Å
618K89.6Confident85.6Confident96 Ų9667.4 Ų67.442%0.41736%0.362SS..THydrogen-bonded Turntrans50.251.7-170.1-60.5-170.2177-167.70111.1C583 F613 D614 T616C583-K618 PolarHBondContact N-O 3.47Å; F613-K618 VanDerWaalsContact CZ-C 3.49Å; F613-K618 HydrophobicContact CZ-CB 4.31Å; D614-K618 WeakPolarHBondContact O-CA 3.46Å; D614-K618 PolarHBondContact O-N 3.2Å; T616-K618 VanDerWaalsContact C-N 3.27Å
619A92.2Very high86.6Confident1 Ų166 Ų661%0.00834%0.342CS..EExtended strand (participates in β ladder)trans-142.6146.2-17200000112.7V580 L581 F613 D614 L617 I621V580-A619 HydrophobicContact CG1-CB 3.79Å; L581-A619 CarbonylContact O-C 3.47Å; L581-A619 WeakPolarHBondContact O-CA 3.04Å; F613-A619 CarbonylContact C-O 3.52Å; F613-A619 WeakPolarHBondContact CA-O 3.33Å; F613-A619 VanDerWaalsContact CD2-C 3.41Å; F613-A619 WeakPolarHBondContact CD2-O 3.26Å; D614-A619 PolarHBondContact N-O 2.99Å; D614-A619 PolarHBondContact O-N 3.25Å; D614-A619 VanDerWaalsContact O-N 3.08Å; L617-A619 VanDerWaalsContact C-N 3.33Å; L617-A619 HydrophobicContact CB-CB 4.11Å; L617-A619 PolarHBondContact O-N 3.13Å; A619-I621 HydrophobicContact CB-CD1 4.25Å
620L93.2Very high87.6Confident0 Ų065.2 Ų65.20%033%0.33CS..EExtended strand (participates in β ladder)trans-73.4124.3161.3175.168.9000108.7V580 L581 W594 L601 L603 P611 V622 Y633V580-L620 WeakPolarHBondContact CA-O 3.32Å; L581-L620 HydrophobicContact CB-CB 4.42Å; L581-L620 PolarHBondContact N-O 2.91Å; L581-L620 PolarHBondContact O-N 3.08Å; W594-L620 HydrophobicContact CD2-CB 4.19Å; W594-L620 HydrophobicContact CD2-CD2 3.8Å; W594-L620 HydrophobicContact CE3-CD2 3.91Å; W594-L620 HydrophobicContact CG-CD2 4.21Å; W594-L620 HydrophobicContact CH2-CB 4.02Å; W594-L620 HydrophobicContact CH2-CD2 4.43Å; W594-L620 HydrophobicContact CZ2-CB 3.43Å; W594-L620 VanDerWaalsContact CZ2-CB 3.43Å; W594-L620 HydrophobicContact CZ2-CD2 4.36Å; W594-L620 HydrophobicContact CZ3-CD2 4.23Å; L601-L620 HydrophobicContact CD2-CD1 4.04Å; L601-L620 HydrophobicContact CD2-CD2 3.66Å; L603-L620 HydrophobicContact CD2-CD1 3.56Å; P611-L620 HydrophobicContact CB-CD1 4.23Å; L620-V622 HydrophobicContact CD1-CG2 4.27Å; L620-V622 HydrophobicContact CD2-CG2 3.84Å; L620-V622 HydrophobicContact CG-CG2 3.76Å; L620-Y633 HydrophobicContact CD2-CD1 3.92Å; L620-Y633 HydrophobicContact CD2-CE1 3.94Å
621I92Very high88.1Confident9 Ų964.7 Ų64.75%0.04633%0.325CS..EExtended strand (participates in β ladder)trans-103.9121.2170.6-44.3-59.3000107.1M579 V580 P611 R612 D614 L617 A619M579-I621 WeakPolarHBondContact O-CA 3.29Å; V580-I621 HydrophobicContact CB-CD1 4.33Å; V580-I621 HydrophobicContact CG1-CD1 3.89Å; V580-I621 HydrophobicContact CG2-CD1 3.89Å; P611-I621 WeakPolarHBondContact CA-O 3.26Å; R612-I621 HydrophobicContact CG-CB 4.05Å; R612-I621 PolarHBondContact N-O 3.24Å; R612-I621 PolarHBondContact O-N 3.5Å; D614-I621 HydrophobicContact CB-CD1 4.31Å; D614-I621 HydrophobicContact CB-CG1 3.94Å; L617-I621 HydrophobicContact CD1-CD1 4.07Å; A619-I621 HydrophobicContact CB-CD1 4.25Å
622V90.6Very high88.5Confident3 Ų366.9 Ų66.92%0.01833%0.328CS..EExtended strand (participates in β ladder)trans-116.6106.5171.7-164.40000107.7M579 P611 L620M579-V622 HydrophobicContact CB-CB 4.33Å; M579-V622 HydrophobicContact CE-CB 3.93Å; M579-V622 HydrophobicContact CE-CG2 3.64Å; M579-V622 PolarHBondContact N-O 2.99Å; M579-V622 PolarHBondContact O-N 3.45Å; P611-V622 HydrophobicContact CB-CG1 4.33Å; P611-V622 HydrophobicContact CB-CG2 4.28Å; P611-V622 HydrophobicContact CG-CG1 4.16Å; L620-V622 HydrophobicContact CD1-CG2 4.27Å; L620-V622 HydrophobicContact CD2-CG2 3.84Å; L620-V622 HydrophobicContact CG-CG2 3.76Å
623P88.6Confident88.6Confident23 Ų2363.5 Ų63.515%0.14932%0.316CS..  trans-72.8157.9-177.531-35.2000112.1D578 G609 G610 A625D578-P623 VanDerWaalsContact OD1-CA 3.22Å; D578-P623 WeakPolarHBondContact OD1-CA 3.12Å; G609-P623 WeakPolarHBondContact O-CG 3.18Å; G610-P623 WeakPolarHBondContact O-CD 3.3Å; P623-A625 PolarHBondContact O-N 3.21Å
624E86.6Confident88.8Confident151 Ų15162.2 Ų62.271%0.70631%0.31SS*.SBendtrans45.358.6173.6-62.5-171.4179.200114D578 G626D578-E624 PolarHBondContact OD1-N 3.25Å; D578-E624 VanDerWaalsContact OD1-N 3.13Å; E624-G626 PolarHBondContact O-N 2.96Å; E624-G626 VanDerWaalsContact O-N 3.12Å
625A85.4Confident89Confident0 Ų059.8 Ų59.80%030%0.297CS..  trans-58.8119.6-167.900000113.3V573 V575 G576 S577 M579 P623V573-A625 HydrophobicContact CB-CB 4.5Å; V573-A625 HydrophobicContact CG1-CB 3.77Å; V575-A625 CarbonylContact C-O 3.55Å; V575-A625 VanDerWaalsContact CA-O 3.25Å; V575-A625 WeakPolarHBondContact CA-O 3.26Å; G576-A625 PolarHBondContact N-O 2.77Å; S577-A625 WeakPolarHBondContact O-CB 3.46Å; S577-A625 PolarHBondContact O-N 3.24Å; M579-A625 HydrophobicContact CB-CB 4.45Å; P623-A625 PolarHBondContact O-N 3.21Å
626G85.1Confident89.3Confident24 Ų2451.9 Ų51.925%0.24727%0.268CS..  trans-104.2163.1178.200000113.2E624 M628 Q629E624-G626 PolarHBondContact O-N 2.96Å; E624-G626 VanDerWaalsContact O-N 3.12Å; G626-M628 PolarHBondContact O-N 3.02Å; G626-M628 VanDerWaalsContact O-N 3.08Å; G626-Q629 WeakPolarHBondContact O-CB 3.39Å; G626-Q629 PolarHBondContact O-N 3.07Å
627Q83.8Confident89.7Confident139 Ų13945.6 Ų45.665%0.6523%0.229SC*.G310 helixtrans-53.9-32.1179-82-175-30.600114V575 Q629 A630V575-Q627 HydrophobicContact CG2-CG 4.48Å; Q627-Q629 PolarHBondContact O-N 2.89Å; Q627-Q629 VanDerWaalsContact O-N 3.17Å; Q627-A630 WeakPolarHBondContact O-CB 3.38Å; Q627-A630 PolarHBondContact O-N 2.64Å; Q627-A630 VanDerWaalsContact O-N 3.11Å
628M83.6Confident89.9Confident183 Ų18342.7 Ų42.790%0.90121%0.213SC*.G310 helixtrans-65.2-12.8176.3-63.9-58.6-65.200114.2G626G626-M628 PolarHBondContact O-N 3.02Å; G626-M628 VanDerWaalsContact O-N 3.08Å
629Q86.5Confident90Very high50 Ų5038.8 Ų38.823%0.23420%0.196CC..G310 helixtrans-97.54.1176.5-56.4176.36.800112.6G626 Q627 Y633G626-Q629 WeakPolarHBondContact O-CB 3.39Å; G626-Q629 PolarHBondContact O-N 3.07Å; Q627-Q629 PolarHBondContact O-N 2.89Å; Q627-Q629 VanDerWaalsContact O-N 3.17Å; Q629-Y633 VanDerWaalsContact O-CE2 3.31Å; Q629-Y633 WeakPolarHBondContact O-CE2 3.38Å; Q629-Y633 PolarHBondContact O-OH 3.02Å; Q629-Y633 VanDerWaalsContact O-OH 3.1Å
630A90.2Very high89.8Confident36 Ų3644.8 Ų44.830%0.29822%0.224SC..  trans-70.3141.4169.400000110.7N597 Q627 V653N597-A630 PolarHBondContact ND2-O 2.95Å; Q627-A630 WeakPolarHBondContact O-CB 3.38Å; Q627-A630 PolarHBondContact O-N 2.64Å; Q627-A630 VanDerWaalsContact O-N 3.11Å; A630-V653 HydrophobicContact CB-CB 4.44Å; A630-V653 HydrophobicContact CB-CG2 4.24Å
631G92.6Very high89.5Confident7 Ų747.5 Ų47.57%0.07225%0.252CS..EExtended strand (participates in β ladder)trans155.6-174-17800000116.1N597 Q650 V651N597-G631 WeakPolarHBondContact OD1-CA 3.41Å; G631-Q650 PolarHBondContact O-NE2 2.83Å; G631-V651 PolarHBondContact N-O 3.28Å; G631-V651 PolarHBondContact O-N 3.48Å
632R93.7Very high89.4Confident83 Ų8347.4 Ų47.431%0.31325%0.252SS..EExtended strand (participates in β ladder)trans-89.3115.8173.2-173.9175.975.7-156.25.4109.7V596 N597 D598 I634 Y649V596-R632 WeakPolarHBondContact CA-O 3.33Å; N597-R632 PolarHBondContact N-O 3.03Å; N597-R632 PolarHBondContact OD1-N 3.07Å; D598-R632 IonicContact OD1-CZ 3.66Å; D598-R632 IonicContact OD1-NE 3.93Å; D598-R632 IonicContact OD1-NH2 2.66Å; D598-R632 PolarHBondContact OD1-NH2 3.41Å; D598-R632 IonicContact OD2-CZ 3.8Å; D598-R632 IonicContact OD2-NH2 2.75Å; D598-R632 PolarHBondContact OD2-NH2 2.81Å; R632-I634 HydrophobicContact CG-CG1 4.38Å; R632-Y649 WeakPolarHBondContact CA-O 3.25Å
633Y93.8Very high89.3Confident6 Ų649.9 Ų49.92%0.02426%0.262CS..EExtended strand (participates in β ladder)trans-100.4138.1173.3-73.8-119.6000109.1M579 L581 W594 V595 V596 L601 L620 Q629 Y649 V651M579-Y633 HydrophobicContact CE-CE1 3.86Å; M579-Y633 HydrophobicContact CE-CE2 4.3Å; L581-Y633 HydrophobicContact CD1-CD1 3.49Å; L581-Y633 VanDerWaalsContact CD1-CD1 3.49Å; L581-Y633 HydrophobicContact CD1-CD2 4.38Å; L581-Y633 HydrophobicContact CD1-CE1 4.1Å; L581-Y633 HydrophobicContact CD1-CG 3.68Å; W594-Y633 HydrophobicContact CE3-CD1 4.31Å; W594-Y633 HydrophobicContact CZ3-CD1 4.44Å; V595-Y633 CarbonylContact O-C 3.45Å; V595-Y633 WeakPolarHBondContact O-CA 3.48Å; V596-Y633 HydrophobicContact CG1-CD2 4.13Å; V596-Y633 HydrophobicContact CG1-CE1 4.36Å; V596-Y633 HydrophobicContact CG1-CE2 3.7Å; V596-Y633 HydrophobicContact CG2-CD1 3.45Å; V596-Y633 VanDerWaalsContact CG2-CD1 3.45Å; V596-Y633 HydrophobicContact CG2-CD2 4.22Å; V596-Y633 HydrophobicContact CG2-CE1 3.35Å; V596-Y633 HydrophobicContact CG2-CE2 4.12Å; V596-Y633 HydrophobicContact CG2-CG 3.87Å; L601-Y633 HydrophobicContact CD2-CE1 4.43Å; L620-Y633 HydrophobicContact CD2-CD1 3.92Å; L620-Y633 HydrophobicContact CD2-CE1 3.94Å; Q629-Y633 VanDerWaalsContact O-CE2 3.31Å; Q629-Y633 WeakPolarHBondContact O-CE2 3.38Å; Q629-Y633 PolarHBondContact O-OH 3.02Å; Q629-Y633 VanDerWaalsContact O-OH 3.1Å; Y633-Y649 PolarHBondContact N-O 2.78Å; Y633-Y649 PolarHBondContact O-N 2.85Å; Y633-V651 HydrophobicContact CD2-CB 4.12Å; Y633-V651 HydrophobicContact CD2-CG2 3.55Å; Y633-V651 HydrophobicContact CE2-CB 4.08Å; Y633-V651 HydrophobicContact CE2-CG2 3.83Å; Y633-V651 HydrophobicContact CG-CG2 4.24Å
634I92.4Very high89.4Confident6 Ų648.9 Ų48.93%0.03126%0.255CS..EExtended strand (participates in β ladder)trans-131.1126.9172.8-53.1177.5000107.8V595 R632 Y636 Q645 E647 R648V595-I634 PolarHBondContact N-O 2.81Å; V595-I634 PolarHBondContact O-N 2.72Å; R632-I634 HydrophobicContact CG-CG1 4.38Å; I634-Y636 HydrophobicContact CB-CE2 3.95Å; I634-Y636 HydrophobicContact CG2-CD2 4.11Å; I634-Y636 HydrophobicContact CG2-CE1 4.23Å; I634-Y636 HydrophobicContact CG2-CE2 3.49Å; I634-Y636 VanDerWaalsContact CG2-CE2 3.49Å; I634-Q645 HydrophobicContact CG2-CG 3.77Å; I634-E647 WeakPolarHBondContact CA-O 3.21Å; I634-R648 HydrophobicContact CG2-CG 4.29Å
635C92.4Very high89.6Confident0 Ų042.9 Ų42.90%023%0.227CC..EExtended strand (participates in β ladder)trans-92.6137.6167.7-165.70000110.5C583 W594 T646 E647C583-C635 HydrophobicContact CB-CB 3.63Å; C583-C635 WeakPolarHBondContact CB-SG 3.41Å; C583-C635 WeakPolarHBondContact SG-CB 3.35Å; C583-C635 CovalentContact SG-SG 2.02Å; C583-C635 PolarHBondContact SG-SG 3.44Å; W594-C635 HydrophobicContact CD2-CB 3.97Å; W594-C635 VanDerWaalsContact CE2-SG 3.54Å; W594-C635 HydrophobicContact CE3-CB 3.94Å; W594-C635 HydrophobicContact CH2-CB 3.73Å; W594-C635 HydrophobicContact CZ2-CB 3.74Å; W594-C635 HydrophobicContact CZ3-CB 3.82Å; C635-T646 PolarHBondContact O-N 3.42Å; C635-T646 PolarHBondContact O-OG1 3.38Å; C635-E647 HydrophobicContact CB-CB 4.26Å; C635-E647 PolarHBondContact N-O 2.89Å
636Y91.6Very high89.7Confident28 Ų2842.9 Ų42.911%0.1123%0.227CC..EExtended strand (participates in β ladder)trans-118.4141.7164.4-55.5-95.9000109.1P557 F593 V595 I634 K643 F644 Q645P557-Y636 HydrophobicContact CB-CD1 3.91Å; P557-Y636 HydrophobicContact CB-CE1 3.47Å; P557-Y636 VanDerWaalsContact CB-CE1 3.47Å; P557-Y636 HydrophobicContact CG-CD1 4.46Å; P557-Y636 HydrophobicContact CG-CE1 3.79Å; F593-Y636 AromaticContact CD1-CD2 3.89Å; F593-Y636 HydrophobicContact CD1-CD2 3.89Å; F593-Y636 HydrophobicContact CD1-CG 4.37Å; F593-Y636 HydrophobicContact CE1-CD2 4.48Å; F593-Y636 PolarHBondContact N-O 3.11Å; F593-Y636 PolarHBondContact O-N 3.22Å; V595-Y636 HydrophobicContact CB-CE2 4.08Å; V595-Y636 HydrophobicContact CG2-CD2 4.12Å; V595-Y636 HydrophobicContact CG2-CE2 3.65Å; I634-Y636 HydrophobicContact CB-CE2 3.95Å; I634-Y636 HydrophobicContact CG2-CD2 4.11Å; I634-Y636 HydrophobicContact CG2-CE1 4.23Å; I634-Y636 HydrophobicContact CG2-CE2 3.49Å; I634-Y636 VanDerWaalsContact CG2-CE2 3.49Å; Y636-K643 HydrophobicContact CD1-CB 4.18Å; Y636-K643 HydrophobicContact CG-CB 4.4Å; Y636-F644 CarbonylContact C-O 3.54Å; Y636-F644 WeakPolarHBondContact CA-O 3.32Å; Y636-Q645 HydrophobicContact CD1-CB 3.75Å; Y636-Q645 HydrophobicContact CD1-CG 4.15Å; Y636-Q645 HydrophobicContact CE1-CB 3.66Å; Y636-Q645 HydrophobicContact CE1-CG 3.77Å
637S92.2Very high89.9Confident0 Ų041.8 Ų41.80%022%0.216CC..EExtended strand (participates in β ladder)trans-91.8121.8165.2-172.50000107.6L585 V586 A590 F644L585-S637 WeakPolarHBondContact CA-OG 3.43Å; V586-S637 PolarHBondContact N-OG 2.98Å; V586-S637 VanDerWaalsContact N-OG 3.09Å; A590-S637 WeakPolarHBondContact CB-OG 3.11Å; S637-F644 PolarHBondContact N-O 3.38Å; S637-F644 WeakPolarHBondContact O-CD2 3.37Å; S637-F644 PolarHBondContact O-N 3.31Å
638E91.3Very high90.3Very high52 Ų5238.8 Ų38.824%0.24320%0.199CC..EExtended strand (participates in β ladder)trans-109.6122.7-176.9-178.6159-147.100112A590 Q591 F593 V642 K643A590-E638 CarbonylContact C-O 3.5Å; A590-E638 VanDerWaalsContact CA-O 3.23Å; A590-E638 WeakPolarHBondContact CA-O 3.49Å; A590-E638 WeakPolarHBondContact CB-O 3.45Å; Q591-E638 PolarHBondContact N-O 3.38Å; Q591-E638 PolarHBondContact O-N 2.8Å; F593-E638 HydrophobicContact CB-CB 4.29Å; E638-V642 VanDerWaalsContact CA-O 3.31Å; E638-V642 WeakPolarHBondContact CA-O 3.27Å; E638-K643 HydrophobicContact CB-CG 4.27Å; E638-K643 HydrophobicContact CG-CG 4.19Å; E638-K643 WeakPolarHBondContact OE1-CE 3.27Å; E638-K643 IonicContact OE1-NZ 3.41Å; E638-K643 WeakPolarHBondContact OE2-CE 3.16Å; E638-K643 IonicContact OE2-NZ 3.69Å; E638-K643 PolarHBondContact OE2-NZ 2.98Å
639E91.8Very high90.7Very high13 Ų1330.5 Ų30.56%0.06116%0.157CC..EExtended strand (participates in β ladder)trans-137.4123.3178.2-171.2174.9-148.400109.5R28 L510 S587 A590 G641 V642R28-E639 IonicContact CZ-OE1 3.63Å; R28-E639 IonicContact CZ-OE2 3.56Å; R28-E639 IonicContact NE-OE1 2.98Å; R28-E639 PolarHBondContact NE-OE1 3.43Å; R28-E639 IonicContact NE-OE2 2.71Å; R28-E639 PolarHBondContact NE-OE2 3.02Å; R28-E639 IonicContact NH2-OE1 3.94Å; R28-E639 IonicContact NH2-OE2 3.88Å; R28-E639 PolarHBondContact NH2-OE2 3.08Å; L510-E639 HydrophobicContact CD1-CB 4.2Å; L510-E639 HydrophobicContact CD1-CG 4.18Å; S587-E639 VanDerWaalsContact CB-OE1 3.3Å; S587-E639 WeakPolarHBondContact CB-OE1 3.01Å; S587-E639 WeakPolarHBondContact CB-OE2 3.27Å; S587-E639 VanDerWaalsContact OG-CD 3.31Å; S587-E639 PolarHBondContact OG-OE1 3.27Å; A590-E639 HydrophobicContact CB-CB 4.04Å; E639-G641 PolarHBondContact O-N 2.91Å; E639-G641 VanDerWaalsContact O-N 3.16Å; E639-V642 PolarHBondContact N-O 2.92Å; E639-V642 WeakPolarHBondContact O-CB 3.06Å; E639-V642 PolarHBondContact O-N 2.94Å
640Q89.1Confident91.1Very high127 Ų12731.7 Ų31.759%0.59316%0.163SC*.THydrogen-bonded Turntrans50.436.5-176-58.5-66.6-13.700114L510 L544 F547 V642L510-Q640 HydrophobicContact CD2-CB 3.74Å; L510-Q640 HydrophobicContact CD2-CG 3.62Å; L544-Q640 HydrophobicContact CD1-CG 4.25Å; F547-Q640 HydrophobicContact CD1-CB 4.11Å; Q640-V642 VanDerWaalsContact C-N 3.3Å; Q640-V642 PolarHBondContact O-N 3.38Å
641G86.6Confident91.3Very high58 Ų5830 Ų3060%0.59815%0.149SC*.THydrogen-bonded Turntrans793.6-177.800000115.2E639E639-G641 PolarHBondContact O-N 2.91Å; E639-G641 VanDerWaalsContact O-N 3.16Å
642V88.9Confident91.3Very high6 Ų631.9 Ų31.94%0.03616%0.164CC..EExtended strand (participates in β ladder)trans-94123174.9-171.40000110.2P506 L510 F547 F554 E638 E639 Q640 F644P506-V642 HydrophobicContact CB-CB 4.45Å; P506-V642 HydrophobicContact CB-CG1 3.69Å; P506-V642 HydrophobicContact CB-CG2 4.3Å; P506-V642 HydrophobicContact CG-CG1 3.97Å; L510-V642 HydrophobicContact CD1-CB 4.37Å; L510-V642 HydrophobicContact CD1-CG2 4.23Å; F547-V642 HydrophobicContact CD1-CG2 4.39Å; F547-V642 HydrophobicContact CE1-CG2 3.82Å; F554-V642 HydrophobicContact CB-CG1 4.47Å; F554-V642 HydrophobicContact CD2-CG1 4.2Å; F554-V642 HydrophobicContact CD2-CG2 3.72Å; F554-V642 HydrophobicContact CE2-CG2 4.18Å; E638-V642 VanDerWaalsContact CA-O 3.31Å; E638-V642 WeakPolarHBondContact CA-O 3.27Å; E639-V642 PolarHBondContact N-O 2.92Å; E639-V642 WeakPolarHBondContact O-CB 3.06Å; E639-V642 PolarHBondContact O-N 2.94Å; Q640-V642 VanDerWaalsContact C-N 3.3Å; Q640-V642 PolarHBondContact O-N 3.38Å; V642-F644 HydrophobicContact CB-CE2 4.15Å; V642-F644 HydrophobicContact CG1-CD2 4.41Å; V642-F644 HydrophobicContact CG1-CE1 4.47Å; V642-F644 HydrophobicContact CG1-CE2 3.97Å; V642-F644 HydrophobicContact CG1-CZ 4.03Å
643K90Very high91.1Very high55 Ų5528.6 Ų28.624%0.23915%0.153CC..EExtended strand (participates in β ladder)trans-98110179.6-65.6-176.5177.8-173.40111.2P557 V558 F593 Y636 E638P557-K643 VanDerWaalsContact CA-O 3.32Å; P557-K643 WeakPolarHBondContact CA-O 3.46Å; V558-K643 PolarHBondContact N-O 3.33Å; F593-K643 HydrophobicContact CD1-CD 3.81Å; F593-K643 HydrophobicContact CE1-CD 4.03Å; F593-K643 VanDerWaalsContact CE1-NZ 3.33Å; F593-K643 HydrophobicContact CG-CD 4.21Å; Y636-K643 HydrophobicContact CD1-CB 4.18Å; Y636-K643 HydrophobicContact CG-CB 4.4Å; E638-K643 HydrophobicContact CB-CG 4.27Å; E638-K643 HydrophobicContact CG-CG 4.19Å; E638-K643 WeakPolarHBondContact OE1-CE 3.27Å; E638-K643 IonicContact OE1-NZ 3.41Å; E638-K643 WeakPolarHBondContact OE2-CE 3.16Å; E638-K643 IonicContact OE2-NZ 3.69Å; E638-K643 PolarHBondContact OE2-NZ 2.98Å
644F90.3Very high90.8Very high2 Ų230.5 Ų30.51%0.00917%0.165CC..EExtended strand (participates in β ladder)trans-92.5118.1172.1-58.5-90.7000109.4P506 D507 L510 V558 I560 V586 Y636 S637 V642 T646P506-F644 HydrophobicContact CB-CE1 4.06Å; P506-F644 HydrophobicContact CB-CZ 3.81Å; P506-F644 HydrophobicContact CG-CE1 4.36Å; D507-F644 HydrophobicContact CB-CE1 4.01Å; D507-F644 HydrophobicContact CB-CZ 4.14Å; L510-F644 HydrophobicContact CD1-CE2 4.09Å; L510-F644 HydrophobicContact CD1-CZ 4.07Å; V558-F644 HydrophobicContact CB-CD1 4.08Å; V558-F644 HydrophobicContact CG1-CD1 4.13Å; V558-F644 HydrophobicContact CG1-CE1 4.45Å; V558-F644 CarbonylContact O-C 3.6Å; V558-F644 VanDerWaalsContact O-CA 3.28Å; V558-F644 WeakPolarHBondContact O-CA 3.41Å; I560-F644 HydrophobicContact CG1-CB 4.46Å; V586-F644 HydrophobicContact CG1-CB 3.89Å; V586-F644 HydrophobicContact CG1-CG 4.11Å; V586-F644 HydrophobicContact CG2-CB 4.38Å; V586-F644 HydrophobicContact CG2-CD2 3.55Å; V586-F644 HydrophobicContact CG2-CE2 3.83Å; V586-F644 HydrophobicContact CG2-CG 3.94Å; V586-F644 HydrophobicContact CG2-CZ 4.43Å; Y636-F644 CarbonylContact C-O 3.54Å; Y636-F644 WeakPolarHBondContact CA-O 3.32Å; S637-F644 PolarHBondContact N-O 3.38Å; S637-F644 WeakPolarHBondContact O-CD2 3.37Å; S637-F644 PolarHBondContact O-N 3.31Å; V642-F644 HydrophobicContact CB-CE2 4.15Å; V642-F644 HydrophobicContact CG1-CD2 4.41Å; V642-F644 HydrophobicContact CG1-CE1 4.47Å; V642-F644 HydrophobicContact CG1-CE2 3.97Å; V642-F644 HydrophobicContact CG1-CZ 4.03Å; F644-T646 WeakPolarHBondContact O-CG2 3.27Å; F644-T646 PolarHBondContact O-N 3.07Å
645Q89.9Confident90.1Very high25 Ų2534.1 Ų34.112%0.11720%0.196CC..EExtended strand (participates in β ladder)trans-75122.9177.8-170.4-164-105.900109.7V558 S559 I634 Y636V558-Q645 PolarHBondContact O-N 3.01Å; S559-Q645 PolarHBondContact OG-NE2 3.22Å; I634-Q645 HydrophobicContact CG2-CG 3.77Å; Y636-Q645 HydrophobicContact CD1-CB 3.75Å; Y636-Q645 HydrophobicContact CD1-CG 4.15Å; Y636-Q645 HydrophobicContact CE1-CB 3.66Å; Y636-Q645 HydrophobicContact CE1-CG 3.77Å
646T88.2Confident89Confident0 Ų037.9 Ų37.90%022%0.222CC..EExtended strand (participates in β ladder)trans-118-44-169.160.60000114.3I560 H565 C583 Q584 V586 C635 F644I560-T646 HydrophobicContact CD1-CG2 3.46Å; I560-T646 VanDerWaalsContact CD1-CG2 3.46Å; H565-T646 WeakPolarHBondContact CA-O 3.12Å; H565-T646 WeakPolarHBondContact CB-O 3.47Å; H565-T646 PolarHBondContact CD2-O 3.19Å; C583-T646 PolarHBondContact SG-OG1 2.87Å; Q584-T646 WeakPolarHBondContact O-CB 3.49Å; Q584-T646 WeakPolarHBondContact O-CG2 3.42Å; Q584-T646 PolarHBondContact O-OG1 2.87Å; V586-T646 HydrophobicContact CG1-CG2 4.28Å; C635-T646 PolarHBondContact O-N 3.42Å; C635-T646 PolarHBondContact O-OG1 3.38Å; F644-T646 WeakPolarHBondContact O-CG2 3.27Å; F644-T646 PolarHBondContact O-N 3.07Å
647E89.2Confident87.2Confident2 Ų239.3 Ų39.31%0.00924%0.24CC..EExtended strand (participates in β ladder)trans-140.4149.4-176.2-73.9-69.6-179.900111.5R569 I634 C635 Y649R569-E647 IonicContact CZ-OE1 3.68Å; R569-E647 IonicContact CZ-OE2 2.86Å; R569-E647 IonicContact NE-OE1 2.7Å; R569-E647 IonicContact NE-OE2 3.18Å; R569-E647 PolarHBondContact NE-OE2 2.75Å; R569-E647 VanDerWaalsContact NH2-CD 3.33Å; R569-E647 IonicContact NH2-OE1 3.54Å; R569-E647 PolarHBondContact NH2-OE1 2.9Å; R569-E647 IonicContact NH2-OE2 3.37Å; R569-E647 PolarHBondContact NH2-OE2 2.69Å; I634-E647 WeakPolarHBondContact CA-O 3.21Å; C635-E647 HydrophobicContact CB-CB 4.26Å; C635-E647 PolarHBondContact N-O 2.89Å; E647-Y649 HydrophobicContact CB-CE2 3.67Å; E647-Y649 HydrophobicContact CG-CE2 4.46Å
648R91.6Very high85.1Confident76 Ų7642.4 Ų42.429%0.28726%0.26SS..EExtended strand (participates in β ladder)trans-137.3121.4-176.5-63.4179.366.1156.9-0.2110.4L568 R569 I634L568-R648 WeakPolarHBondContact CA-O 3.45Å; L568-R648 HydrophobicContact CD1-CB 4.05Å; R569-R648 PolarHBondContact N-O 2.84Å; I634-R648 HydrophobicContact CG2-CG 4.29Å
649Y93.1Very high82.8Confident8 Ų846.4 Ų46.43%0.03129%0.288CS..EExtended strand (participates in β ladder)trans-120.5145.7179.5-56.8-92.3000111.9R569 V571 L581 P582 W594 R632 Y633 E647R569-Y649 HydrophobicContact CB-CD1 3.68Å; R569-Y649 HydrophobicContact CB-CE1 3.91Å; R569-Y649 HydrophobicContact CG-CD1 4.47Å; R569-Y649 HydrophobicContact CG-CE1 4.29Å; R569-Y649 CarbonylContact O-C 3.6Å; R569-Y649 VanDerWaalsContact O-CA 3.23Å; R569-Y649 WeakPolarHBondContact O-CA 3.41Å; V571-Y649 HydrophobicContact CG2-CD1 3.71Å; V571-Y649 HydrophobicContact CG2-CE1 4.44Å; L581-Y649 HydrophobicContact CB-CD2 4.22Å; L581-Y649 HydrophobicContact CB-CE2 4.1Å; L581-Y649 HydrophobicContact CD1-CD2 4.2Å; L581-Y649 HydrophobicContact CD1-CG 4.25Å; L581-Y649 HydrophobicContact CD2-CD1 3.88Å; L581-Y649 HydrophobicContact CD2-CD2 4.45Å; L581-Y649 HydrophobicContact CD2-CE1 4.26Å; L581-Y649 HydrophobicContact CD2-CG 4Å; P582-Y649 WeakPolarHBondContact O-CE2 3.44Å; P582-Y649 PolarHBondContact O-OH 3.02Å; W594-Y649 HydrophobicContact CH2-CD2 4.32Å; W594-Y649 HydrophobicContact CH2-CE2 4.04Å; W594-Y649 HydrophobicContact CZ3-CD2 4.17Å; W594-Y649 HydrophobicContact CZ3-CE2 4.33Å; R632-Y649 WeakPolarHBondContact CA-O 3.25Å; Y633-Y649 PolarHBondContact N-O 2.78Å; Y633-Y649 PolarHBondContact O-N 2.85Å; E647-Y649 HydrophobicContact CB-CE2 3.67Å; E647-Y649 HydrophobicContact CG-CE2 4.46Å
650Q94.6Very high80.3Confident75 Ų7553.1 Ų53.135%0.3532%0.317SS..EExtended strand (participates in β ladder)trans-113.5105.2165.1-174.462.151.800108L568 R569 N570 V571 G631L568-Q650 HydrophobicContact CD1-CB 4.14Å; L568-Q650 HydrophobicContact CD2-CB 4.16Å; L568-Q650 HydrophobicContact CG-CB 4.16Å; R569-Q650 PolarHBondContact O-N 3.11Å; N570-Q650 WeakPolarHBondContact CA-O 3.36Å; V571-Q650 PolarHBondContact N-O 2.89Å; G631-Q650 PolarHBondContact O-NE2 2.83Å
651V94.1Very high78Confident2 Ų255.3 Ų55.31%0.01233%0.329CS..EExtended strand (participates in β ladder)trans-93.3129.8-176.4179.70000109.8V571 M579 L581 G631 Y633 V653V571-V651 CarbonylContact O-C 3.48Å; V571-V651 WeakPolarHBondContact O-CA 3.28Å; M579-V651 HydrophobicContact CE-CG1 4.36Å; M579-V651 HydrophobicContact CE-CG2 4.38Å; M579-V651 HydrophobicContact SD-CB 4.24Å; M579-V651 HydrophobicContact SD-CG1 3.52Å; M579-V651 VanDerWaalsContact SD-CG1 3.52Å; M579-V651 HydrophobicContact SD-CG2 3.64Å; L581-V651 HydrophobicContact CD1-CG2 4.06Å; L581-V651 HydrophobicContact CD2-CG2 4.38Å; G631-V651 PolarHBondContact N-O 3.28Å; G631-V651 PolarHBondContact O-N 3.48Å; Y633-V651 HydrophobicContact CD2-CB 4.12Å; Y633-V651 HydrophobicContact CD2-CG2 3.55Å; Y633-V651 HydrophobicContact CE2-CB 4.08Å; Y633-V651 HydrophobicContact CE2-CG2 3.83Å; Y633-V651 HydrophobicContact CG-CG2 4.24Å; V651-V653 HydrophobicContact CG1-CG2 4.03Å
652A92.3Very high75.5Confident45 Ų4560.5 Ų60.537%0.37234%0.338SS..EExtended strand (participates in β ladder)trans-120.5124.716800000109.4V571 T572 V573V571-A652 PolarHBondContact O-N 3.3Å; T572-A652 WeakPolarHBondContact CA-O 3.49Å; T572-A652 HydrophobicContact CG2-CB 4.46Å; V573-A652 PolarHBondContact N-O 2.82Å
653V89.4Confident73Confident14 Ų1464.1 Ų64.19%0.08537%0.368CS..EExtended strand (participates in β ladder)trans-104.3124.8179-174.60000109.5V573 V575 A630 V651V573-V653 CarbonylContact O-C 3.59Å; V573-V653 VanDerWaalsContact O-CA 3.3Å; V573-V653 WeakPolarHBondContact O-CA 3.44Å; V575-V653 HydrophobicContact CG2-CG1 3.73Å; A630-V653 HydrophobicContact CB-CB 4.44Å; A630-V653 HydrophobicContact CB-CG2 4.24Å; V651-V653 HydrophobicContact CG1-CG2 4.03Å
654V87.9Confident70.6Confident46 Ų4672 Ų7228%0.27940%0.396SS..EExtended strand (participates in β ladder)trans-119.5137.5-170.5-71.40000112V573 V574 V575 S656V573-V654 WeakPolarHBondContact O-CG2 3.29Å; V573-V654 PolarHBondContact O-N 2.71Å; V574-V654 CarbonylContact C-O 3.53Å; V574-V654 WeakPolarHBondContact CA-O 3.45Å; V574-V654 HydrophobicContact CG2-CG2 4.42Å; V575-V654 PolarHBondContact N-O 3.42Å; V654-S656 WeakPolarHBondContact CB-O 3.49Å; V654-S656 WeakPolarHBondContact CG2-O 3.37Å; V654-S656 PolarHBondContact O-N 3.29Å
655A78.6Confident67.9Low82 Ų8274.9 Ų74.968%0.67842%0.421SS*.SBendtrans-66.2-21.2-171.100000114.5
656S68Low65.6Low80 Ų8079.9 Ų79.956%0.55946%0.455SS*.SBendtrans-138.3165.6165.560.50000107.9V654V654-S656 WeakPolarHBondContact CB-O 3.49Å; V654-S656 WeakPolarHBondContact CG2-O 3.37Å; V654-S656 PolarHBondContact O-N 3.29Å
657A54.8Low63.6Low57 Ų5785.4 Ų85.447%0.47149%0.485SS..  trans-50.4136.9163.200000108.8V574 V659V574-A657 HydrophobicContact CG2-CB 3.97Å; A657-V659 PolarHBondContact O-N 2.64Å; A657-V659 VanDerWaalsContact O-N 3.13Å
658P48.2Very low61.7Low65 Ų6590 Ų9042%0.42252%0.518SS..  trans-61.1125.1172.927.5-31.1000106.2F660P658-F660 HydrophobicContact CG-CD2 4.16Å; P658-F660 HydrophobicContact CG-CE2 4.04Å; P658-F660 PolarHBondContact O-N 3.24Å
659V42.7Very low60.1Low137 Ų13789.6 Ų89.683%0.8353%0.526SS*.  trans-66.391.8164179.90000105.2A657 M661A657-V659 PolarHBondContact O-N 2.64Å; A657-V659 VanDerWaalsContact O-N 3.13Å; V659-M661 VanDerWaalsContact C-N 3.3Å; V659-M661 PolarHBondContact O-N 2.74Å
660F39.3Very low58.4Low154 Ų15494 Ų9468%0.67555%0.548SS*.  trans-53.1107.6154.1-85-93.7000105.2P658 E662P658-F660 HydrophobicContact CG-CD2 4.16Å; P658-F660 HydrophobicContact CG-CE2 4.04Å; P658-F660 PolarHBondContact O-N 3.24Å; F660-E662 PolarHBondContact O-N 3.46Å; F660-E662 VanDerWaalsContact O-N 3.13Å
661M39.7Very low56.9Low173 Ų17392.6 Ų92.685%0.85255%0.554SS**  trans-48.2121.5142.7-84.2-172.163.400105.3V659 A663V659-M661 VanDerWaalsContact C-N 3.3Å; V659-M661 PolarHBondContact O-N 2.74Å; M661-A663 PolarHBondContact O-N 2.88Å
662E35.6Very low55.5Low167 Ų16798.6 Ų98.678%0.7859%0.585SS**  trans-45.799.3-175.9-161.786.8-162.100109.3F660 R664F660-E662 PolarHBondContact O-N 3.46Å; F660-E662 VanDerWaalsContact O-N 3.13Å; E662-R664 PolarHBondContact O-N 3.2Å
663A35.8Very low54.5Low81 Ų81101.9 Ų101.967%0.66959%0.592SS**  trans-7383.917300000104.4M661 A665M661-A663 PolarHBondContact O-N 2.88Å; A663-A665 PolarHBondContact O-N 2.76Å
664R39Very low53.8Low220 Ų220108.2 Ų108.283%0.8361%0.614SS**  trans-30.6112.8-164.8-83.7-173.6168.499.6-4.9110E662 P666E662-R664 PolarHBondContact O-N 3.2Å; R664-P666 VanDerWaalsContact O-N 3.17Å
665A34.5Very low53.3Low64 Ų64110.3 Ų110.353%0.52963%0.627SS.*  trans-50.2127.4168.500000107.3A663 D667A663-A665 PolarHBondContact O-N 2.76Å; A665-D667 PolarHBondContact O-N 3.14Å; A665-D667 VanDerWaalsContact O-N 3.12Å
666P40.4Very low53.4Low129 Ų129111.3 Ų111.384%0.83862%0.62SS**SBendtrans-56.3124.4176.124.3-33000107.2R664 S668R664-P666 VanDerWaalsContact O-N 3.17Å; P666-S668 PolarHBondContact O-N 3.46Å
667D46.6Very low54.1Low116 Ų116110.3 Ų110.362%0.6261%0.611SS**  trans-45.1131.5-146.5-73.8-59.1000114.6A665 S669 M670A665-D667 PolarHBondContact O-N 3.14Å; A665-D667 VanDerWaalsContact O-N 3.12Å; D667-S669 VanDerWaalsContact CB-OG 3.24Å; D667-S669 WeakPolarHBondContact CB-OG 3.37Å; D667-S669 PolarHBondContact O-N 3.38Å; D667-S669 PolarHBondContact O-OG 2.83Å; D667-M670 PolarHBondContact O-N 3.03Å
668S50.4Low55.6Low100 Ų100113 Ų11370%0.69962%0.615SS**THydrogen-bonded Turntrans-61.8-0.9168.954.80000113.4P666 M670 G671 L672P666-S668 PolarHBondContact O-N 3.46Å; S668-M670 PolarHBondContact O-N 3.42Å; S668-G671 PolarHBondContact O-N 2.04Å; S668-L672 PolarHBondContact O-N 2.7Å
669S56.8Low57.4Low67 Ų67113.7 Ų113.747%0.46962%0.619SS.*Hα-helixtrans-50-31.3163.470.90000112.8D667 G671 L672 F673D667-S669 VanDerWaalsContact CB-OG 3.24Å; D667-S669 WeakPolarHBondContact CB-OG 3.37Å; D667-S669 PolarHBondContact O-N 3.38Å; D667-S669 PolarHBondContact O-OG 2.83Å; S669-G671 PolarHBondContact O-N 2.93Å; S669-L672 PolarHBondContact O-N 2.79Å; S669-F673 WeakPolarHBondContact O-CB 3.18Å; S669-F673 PolarHBondContact O-N 2.77Å
670M57.2Low59.6Low100 Ų100112 Ų11249%0.49360%0.604SS.*Hα-helixtrans-62.9-39.1175.4-86.4-85.281.400112.9D667 S668 F673 W674D667-M670 PolarHBondContact O-N 3.03Å; S668-M670 PolarHBondContact O-N 3.42Å; M670-F673 HydrophobicContact CE-CB 3.94Å; M670-F673 HydrophobicContact CE-CD1 3.43Å; M670-F673 VanDerWaalsContact CE-CD1 3.43Å; M670-F673 HydrophobicContact CE-CE1 4.09Å; M670-F673 HydrophobicContact CE-CG 3.82Å; M670-F673 PolarHBondContact O-N 3.1Å; M670-W674 PolarHBondContact O-N 3.35Å
671G63.7Low62.1Low46 Ų46106.3 Ų106.347%0.47459%0.59SS.*Hα-helixtrans-65.6-46.9176.800000111.6S668 S669 F673 W674 V675S668-G671 PolarHBondContact O-N 2.04Å; S669-G671 PolarHBondContact O-N 2.93Å; G671-F673 PolarHBondContact O-N 3.5Å; G671-W674 PolarHBondContact O-N 2.91Å; G671-V675 WeakPolarHBondContact O-CG2 3.29Å; G671-V675 PolarHBondContact O-N 2.79Å
672L65.8Low64.4Low127 Ų127100.6 Ų100.667%0.66557%0.57SS**Hα-helixtrans-61.8-41.9174.1-79.2164.5000112.1S668 S669 V675 L676S668-L672 PolarHBondContact O-N 2.7Å; S669-L672 PolarHBondContact O-N 2.79Å; L672-V675 PolarHBondContact O-N 3Å; L672-L676 WeakPolarHBondContact O-CB 3.3Å; L672-L676 PolarHBondContact O-N 3.21Å
673F71.1Confident67Low115 Ų11594.7 Ų94.750%0.50455%0.55SS..Hα-helixtrans-64.2-43.5177.7-178.7-90000111.7S669 M670 G671 L676 V677S669-F673 WeakPolarHBondContact O-CB 3.18Å; S669-F673 PolarHBondContact O-N 2.77Å; M670-F673 HydrophobicContact CE-CB 3.94Å; M670-F673 HydrophobicContact CE-CD1 3.43Å; M670-F673 VanDerWaalsContact CE-CD1 3.43Å; M670-F673 HydrophobicContact CE-CE1 4.09Å; M670-F673 HydrophobicContact CE-CG 3.82Å; M670-F673 PolarHBondContact O-N 3.1Å; G671-F673 PolarHBondContact O-N 3.5Å; F673-L676 CarbonylContact O-C 3.53Å; F673-L676 PolarHBondContact O-N 2.76Å; F673-V677 HydrophobicContact CD1-CG2 3.92Å; F673-V677 HydrophobicContact CE1-CG2 3.61Å; F673-V677 HydrophobicContact CE2-CG2 4.45Å; F673-V677 HydrophobicContact CG-CG2 4.48Å; F673-V677 HydrophobicContact CZ-CG2 3.9Å; F673-V677 WeakPolarHBondContact O-CB 3.46Å; F673-V677 VanDerWaalsContact O-CG2 3.31Å; F673-V677 WeakPolarHBondContact O-CG2 3.39Å; F673-V677 PolarHBondContact O-N 3.32Å
674W73.9Confident69.6Low147 Ų14794.4 Ų94.456%0.55754%0.542SS*.Hα-helixtrans-65.1-38.6174.4-81.7111000112.1M670 G671 L676 V677 I678M670-W674 PolarHBondContact O-N 3.35Å; G671-W674 PolarHBondContact O-N 2.91Å; W674-L676 VanDerWaalsContact C-N 3.34Å; W674-L676 PolarHBondContact O-N 2.82Å; W674-V677 HydrophobicContact CE3-CG1 4.4Å; W674-V677 HydrophobicContact CZ3-CG1 4.43Å; W674-V677 PolarHBondContact O-N 2.69Å; W674-I678 VanDerWaalsContact O-CB 3.3Å; W674-I678 WeakPolarHBondContact O-CB 3.43Å; W674-I678 WeakPolarHBondContact O-CD1 3.13Å; W674-I678 WeakPolarHBondContact O-CG1 3.25Å; W674-I678 PolarHBondContact O-N 2.86Å
675V78Confident72.1Confident90 Ų9089.5 Ų89.555%0.54553%0.531SS..Hα-helixtrans-62.7-40.5171.3170.80000111.4G671 L672 I678 T679G671-V675 WeakPolarHBondContact O-CG2 3.29Å; G671-V675 PolarHBondContact O-N 2.79Å; L672-V675 PolarHBondContact O-N 3Å; V675-I678 PolarHBondContact O-N 2.65Å; V675-T679 HydrophobicContact CG1-CG2 4.47Å; V675-T679 WeakPolarHBondContact O-CB 3.03Å; V675-T679 WeakPolarHBondContact O-CG2 3.38Å; V675-T679 PolarHBondContact O-N 3.17Å; V675-T679 PolarHBondContact O-OG1 3.48Å
676L79.9Confident74.8Confident103 Ų10392.2 Ų92.254%0.53954%0.537SS..Hα-helixtrans-69.2-37.9178.5-144.7161.5000111.5L672 F673 W674 T679 L680L672-L676 WeakPolarHBondContact O-CB 3.3Å; L672-L676 PolarHBondContact O-N 3.21Å; F673-L676 CarbonylContact O-C 3.53Å; F673-L676 PolarHBondContact O-N 2.76Å; W674-L676 VanDerWaalsContact C-N 3.34Å; W674-L676 PolarHBondContact O-N 2.82Å; L676-T679 WeakPolarHBondContact CA-OG1 3.31Å; L676-T679 PolarHBondContact O-OG1 3.36Å; L676-L680 HydrophobicContact CD2-CD1 3.51Å; L676-L680 HydrophobicContact CD2-CG 3.97Å; L676-L680 VanDerWaalsContact O-CB 3.23Å; L676-L680 WeakPolarHBondContact O-CB 2.97Å; L676-L680 WeakPolarHBondContact O-CG 3.33Å; L676-L680 PolarHBondContact O-N 3.1Å
677V83.5Confident77.2Confident59 Ų5991.9 Ų91.936%0.35853%0.527SS..Hα-helixtrans-69.5-39.8173.5167.40000111.9F673 W674 G681F673-V677 HydrophobicContact CD1-CG2 3.92Å; F673-V677 HydrophobicContact CE1-CG2 3.61Å; F673-V677 HydrophobicContact CE2-CG2 4.45Å; F673-V677 HydrophobicContact CG-CG2 4.48Å; F673-V677 HydrophobicContact CZ-CG2 3.9Å; F673-V677 WeakPolarHBondContact O-CB 3.46Å; F673-V677 VanDerWaalsContact O-CG2 3.31Å; F673-V677 WeakPolarHBondContact O-CG2 3.39Å; F673-V677 PolarHBondContact O-N 3.32Å; W674-V677 HydrophobicContact CE3-CG1 4.4Å; W674-V677 HydrophobicContact CZ3-CG1 4.43Å; W674-V677 PolarHBondContact O-N 2.69Å; V677-G681 WeakPolarHBondContact O-CA 3.35Å; V677-G681 PolarHBondContact O-N 2.79Å
678I86.9Confident79.3Confident112 Ų11291.5 Ų91.557%0.57452%0.524SS*.Hα-helixtrans-69.2-40.8176.7-71.2164.9000110.6W674 V675 G681 A682W674-I678 VanDerWaalsContact O-CB 3.3Å; W674-I678 WeakPolarHBondContact O-CB 3.43Å; W674-I678 WeakPolarHBondContact O-CD1 3.13Å; W674-I678 WeakPolarHBondContact O-CG1 3.25Å; W674-I678 PolarHBondContact O-N 2.86Å; V675-I678 PolarHBondContact O-N 2.65Å; I678-G681 PolarHBondContact O-N 2.7Å; I678-A682 WeakPolarHBondContact O-CB 3.09Å; I678-A682 PolarHBondContact O-N 3.11Å
679T84.9Confident81.1Confident80 Ų8090.6 Ų90.649%0.49152%0.515SS..Hα-helixtrans-71.4-40.5176.749.90000112.4V675 L676 G681 A682 A683V675-T679 HydrophobicContact CG1-CG2 4.47Å; V675-T679 WeakPolarHBondContact O-CB 3.03Å; V675-T679 WeakPolarHBondContact O-CG2 3.38Å; V675-T679 PolarHBondContact O-N 3.17Å; V675-T679 PolarHBondContact O-OG1 3.48Å; L676-T679 WeakPolarHBondContact CA-OG1 3.31Å; L676-T679 PolarHBondContact O-OG1 3.36Å; T679-G681 VanDerWaalsContact C-N 3.33Å; T679-A682 PolarHBondContact O-N 2.57Å; T679-A683 VanDerWaalsContact O-CB 3.28Å; T679-A683 WeakPolarHBondContact O-CB 3.49Å; T679-A683 PolarHBondContact O-N 2.95Å
680L88.7Confident82.6Confident101 Ų10189.5 Ų89.553%0.52951%0.51SS..Hα-helixtrans-62.5-39.5168.8-80.4171.9000112L676 A683 C684L676-L680 HydrophobicContact CD2-CD1 3.51Å; L676-L680 HydrophobicContact CD2-CG 3.97Å; L676-L680 VanDerWaalsContact O-CB 3.23Å; L676-L680 WeakPolarHBondContact O-CB 2.97Å; L676-L680 WeakPolarHBondContact O-CG 3.33Å; L676-L680 PolarHBondContact O-N 3.1Å; L680-A683 PolarHBondContact O-N 2.94Å; L680-C684 VanDerWaalsContact O-CB 3.28Å; L680-C684 WeakPolarHBondContact O-CB 3.2Å; L680-C684 PolarHBondContact O-N 3.14Å; L680-C684 PolarHBondContact O-SG 2.85Å
681G91.1Very high84.1Confident36 Ų3687.4 Ų87.437%0.37151%0.508SS..Hα-helixtrans-62.4-47.6176.100000111.9V677 I678 T679 C684 L685V677-G681 WeakPolarHBondContact O-CA 3.35Å; V677-G681 PolarHBondContact O-N 2.79Å; I678-G681 PolarHBondContact O-N 2.7Å; T679-G681 VanDerWaalsContact C-N 3.33Å; G681-C684 PolarHBondContact O-N 2.88Å; G681-L685 VanDerWaalsContact O-CB 3.31Å; G681-L685 WeakPolarHBondContact O-CB 3.16Å; G681-L685 PolarHBondContact O-N 3Å
682A89.1Confident85.2Confident52 Ų5289.5 Ų89.543%0.4351%0.508SS..Hα-helixtrans-63.2-42.8174.800000112.1I678 T679 L685 L686I678-A682 WeakPolarHBondContact O-CB 3.09Å; I678-A682 PolarHBondContact O-N 3.11Å; T679-A682 PolarHBondContact O-N 2.57Å; A682-L685 PolarHBondContact O-N 3.26Å; A682-L686 WeakPolarHBondContact O-CB 3.43Å; A682-L686 WeakPolarHBondContact O-CG 3.29Å; A682-L686 PolarHBondContact O-N 3.08Å
683A91.1Very high86.1Confident43 Ų4389.9 Ų89.936%0.35550%0.501SS..Hα-helixtrans-63.5-43.3175.400000111.9T679 L680 L686 L687T679-A683 VanDerWaalsContact O-CB 3.28Å; T679-A683 WeakPolarHBondContact O-CB 3.49Å; T679-A683 PolarHBondContact O-N 2.95Å; L680-A683 PolarHBondContact O-N 2.94Å; A683-L686 PolarHBondContact O-N 3.16Å; A683-L687 WeakPolarHBondContact O-CB 3.44Å; A683-L687 VanDerWaalsContact O-CG 3.25Å; A683-L687 WeakPolarHBondContact O-CG 3.44Å; A683-L687 PolarHBondContact O-N 2.85Å
684C89.6Confident86.7Confident76 Ų7689.1 Ų89.151%0.51450%0.502SS..Hα-helixtrans-64.2-39.5174.3-720000111.8L680 G681 L687 L688L680-C684 VanDerWaalsContact O-CB 3.28Å; L680-C684 WeakPolarHBondContact O-CB 3.2Å; L680-C684 PolarHBondContact O-N 3.14Å; L680-C684 PolarHBondContact O-SG 2.85Å; G681-C684 PolarHBondContact O-N 2.88Å; C684-L687 PolarHBondContact O-N 2.79Å; C684-L688 WeakPolarHBondContact O-CB 3.38Å; C684-L688 PolarHBondContact O-N 2.92Å
685L91.3Very high87Confident116 Ų11690.3 Ų90.361%0.60751%0.506SS*.Hα-helixtrans-68.6-41.2178.2-159.1157.2000111G681 A682 L688 V689G681-L685 VanDerWaalsContact O-CB 3.31Å; G681-L685 WeakPolarHBondContact O-CB 3.16Å; G681-L685 PolarHBondContact O-N 3Å; A682-L685 PolarHBondContact O-N 3.26Å; L685-L688 PolarHBondContact O-N 2.99Å; L685-V689 HydrophobicContact CD2-CG2 4.03Å; L685-V689 WeakPolarHBondContact O-CB 3.39Å; L685-V689 WeakPolarHBondContact O-CG2 3.15Å; L685-V689 PolarHBondContact O-N 2.84Å
686L90.8Very high87Confident122 Ų12295.3 Ų95.364%0.63952%0.516SS*.Hα-helixtrans-62.1-43.9171.1-74.4169.9000112.1A682 A683 L688 V689 A690A682-L686 WeakPolarHBondContact O-CB 3.43Å; A682-L686 WeakPolarHBondContact O-CG 3.29Å; A682-L686 PolarHBondContact O-N 3.08Å; A683-L686 PolarHBondContact O-N 3.16Å; L686-L688 VanDerWaalsContact C-N 3.33Å; L686-L688 PolarHBondContact O-N 3.15Å; L686-V689 PolarHBondContact O-N 2.87Å; L686-A690 VanDerWaalsContact O-CB 3.28Å; L686-A690 WeakPolarHBondContact O-CB 3.28Å; L686-A690 PolarHBondContact O-N 2.7Å
687L90.6Very high87Confident121 Ų12198 Ų9863%0.63452%0.519SS*.Hα-helixtrans-65-35174.8-75.1169.5000112.3A683 C684 A690 A691A683-L687 WeakPolarHBondContact O-CB 3.44Å; A683-L687 VanDerWaalsContact O-CG 3.25Å; A683-L687 WeakPolarHBondContact O-CG 3.44Å; A683-L687 PolarHBondContact O-N 2.85Å; C684-L687 PolarHBondContact O-N 2.79Å; L687-A690 PolarHBondContact O-N 3.42Å; L687-A691 WeakPolarHBondContact O-CB 3.35Å; L687-A691 PolarHBondContact O-N 3.48Å
688L90.9Very high86.2Confident108 Ų108100.2 Ų100.257%0.56553%0.528SS*.Hα-helixtrans-73.3-39.4177.3-162.8157.7000110.9C684 L685 L686 A691 L692C684-L688 WeakPolarHBondContact O-CB 3.38Å; C684-L688 PolarHBondContact O-N 2.92Å; L685-L688 PolarHBondContact O-N 2.99Å; L686-L688 VanDerWaalsContact C-N 3.33Å; L686-L688 PolarHBondContact O-N 3.15Å; L688-A691 PolarHBondContact O-N 3.01Å; L688-L692 HydrophobicContact CD2-CD1 3.61Å; L688-L692 HydrophobicContact CD2-CG 4.05Å; L688-L692 WeakPolarHBondContact O-CB 3.45Å; L688-L692 VanDerWaalsContact O-CG 3.31Å; L688-L692 WeakPolarHBondContact O-CG 3.43Å; L688-L692 PolarHBondContact O-N 3.31Å
689V89.6Confident85.4Confident82 Ų82102.1 Ų102.150%0.49753%0.532SS..Hα-helixtrans-63-44.2169.7168.60000110.9L685 L686 L692 Y693L685-V689 HydrophobicContact CD2-CG2 4.03Å; L685-V689 WeakPolarHBondContact O-CB 3.39Å; L685-V689 WeakPolarHBondContact O-CG2 3.15Å; L685-V689 PolarHBondContact O-N 2.84Å; L686-V689 PolarHBondContact O-N 2.87Å; V689-L692 PolarHBondContact O-N 2.64Å; V689-Y693 VanDerWaalsContact O-CB 3.32Å; V689-Y693 WeakPolarHBondContact O-CB 3.43Å; V689-Y693 PolarHBondContact O-N 2.8Å
690A88.1Confident84.5Confident44 Ų44104 Ų10436%0.36454%0.539SS..Hα-helixtrans-63.1-41.417500000111.8L686 L687 Y693 L694L686-A690 VanDerWaalsContact O-CB 3.28Å; L686-A690 WeakPolarHBondContact O-CB 3.28Å; L686-A690 PolarHBondContact O-N 2.7Å; L687-A690 PolarHBondContact O-N 3.42Å; A690-Y693 PolarHBondContact O-N 3.21Å; A690-L694 VanDerWaalsContact O-CB 3.28Å; A690-L694 WeakPolarHBondContact O-CB 3.47Å; A690-L694 VanDerWaalsContact O-CG 3.28Å; A690-L694 WeakPolarHBondContact O-CG 3.41Å; A690-L694 PolarHBondContact O-N 3.29Å
691A87.8Confident83.1Confident55 Ų55102.3 Ų102.346%0.45554%0.539SS..Hα-helixtrans-66.8-38.2175.200000112.2L687 L688 R695L687-A691 WeakPolarHBondContact O-CB 3.35Å; L687-A691 PolarHBondContact O-N 3.48Å; L688-A691 PolarHBondContact O-N 3.01Å; A691-R695 WeakPolarHBondContact O-CB 3.37Å; A691-R695 PolarHBondContact O-N 2.86Å
692L86.8Confident81.5Confident91 Ų91106.1 Ų106.148%0.47655%0.55SS..Hα-helixtrans-69.5-36.8173.2-74.2177000112.2L688 V689 R695 R696L688-L692 HydrophobicContact CD2-CD1 3.61Å; L688-L692 HydrophobicContact CD2-CG 4.05Å; L688-L692 WeakPolarHBondContact O-CB 3.45Å; L688-L692 VanDerWaalsContact O-CG 3.31Å; L688-L692 WeakPolarHBondContact O-CG 3.43Å; L688-L692 PolarHBondContact O-N 3.31Å; V689-L692 PolarHBondContact O-N 2.64Å; L692-R695 PolarHBondContact O-N 3.41Å; L692-R696 WeakPolarHBondContact O-CB 3.32Å; L692-R696 PolarHBondContact O-N 3.22Å
693Y85.2Confident79.8Confident134 Ų134106.9 Ų106.953%0.52556%0.563SS.*Hα-helixtrans-65.2-48.3172.9178.2-90.2000111.1V689 A690 R695 R696 R697V689-Y693 VanDerWaalsContact O-CB 3.32Å; V689-Y693 WeakPolarHBondContact O-CB 3.43Å; V689-Y693 PolarHBondContact O-N 2.8Å; A690-Y693 PolarHBondContact O-N 3.21Å; Y693-R695 PolarHBondContact O-N 2.96Å; Y693-R696 WeakPolarHBondContact O-CB 3.49Å; Y693-R696 PolarHBondContact O-N 3.11Å; Y693-R697 HydrophobicContact CE1-CG 4.22Å; Y693-R697 PolarHBondContact O-N 3.46Å; Y693-R697 PolarHBondContact OH-NE 2.93Å
694L82.3Confident77.8Confident99 Ų99113.9 Ų113.952%0.51859%0.585SS.*Hα-helixtrans-62.2-40.3174.4-75.5166.9000111.5A690 R697 L698A690-L694 VanDerWaalsContact O-CB 3.28Å; A690-L694 WeakPolarHBondContact O-CB 3.47Å; A690-L694 VanDerWaalsContact O-CG 3.28Å; A690-L694 WeakPolarHBondContact O-CG 3.41Å; A690-L694 PolarHBondContact O-N 3.29Å; L694-R697 CarbonylContact O-C 3.59Å; L694-R697 PolarHBondContact O-N 2.77Å; L694-L698 WeakPolarHBondContact O-CB 3.49Å; L694-L698 WeakPolarHBondContact O-CD1 3.42Å; L694-L698 PolarHBondContact O-N 2.84Å
695R80.4Confident75.9Confident172 Ų172113.3 Ų113.365%0.64959%0.592SS**Hα-helixtrans-68.3-32.5175.2-166.8177.8-169.8-163.34.6112.3A691 L692 Y693 K699A691-R695 WeakPolarHBondContact O-CB 3.37Å; A691-R695 PolarHBondContact O-N 2.86Å; L692-R695 PolarHBondContact O-N 3.41Å; Y693-R695 PolarHBondContact O-N 2.96Å; R695-K699 WeakPolarHBondContact O-CB 3.46Å; R695-K699 WeakPolarHBondContact O-CG 3.33Å; R695-K699 PolarHBondContact O-N 3.48Å
696R79.3Confident73.6Confident196 Ų196112.1 Ų112.174%0.7460%0.599SS**Hα-helixtrans-66.6-46167.7-87.7-176.5166.4-177.6-3.5111.3L692 Y693 K699 L700L692-R696 WeakPolarHBondContact O-CB 3.32Å; L692-R696 PolarHBondContact O-N 3.22Å; Y693-R696 WeakPolarHBondContact O-CB 3.49Å; Y693-R696 PolarHBondContact O-N 3.11Å; R696-K699 PolarHBondContact O-N 3.04Å; R696-L700 WeakPolarHBondContact O-CB 3.27Å; R696-L700 WeakPolarHBondContact O-CG 3.29Å; R696-L700 PolarHBondContact O-N 3.32Å
697R78.4Confident71Confident160 Ų160114.1 Ų114.160%0.60461%0.61SS**Hα-helixtrans-60-44.3173.8-98.5-166.2176.7-123.54.6112.2Y693 L694 L700 A701Y693-R697 HydrophobicContact CE1-CG 4.22Å; Y693-R697 PolarHBondContact O-N 3.46Å; Y693-R697 PolarHBondContact OH-NE 2.93Å; L694-R697 CarbonylContact O-C 3.59Å; L694-R697 PolarHBondContact O-N 2.77Å; R697-L700 CarbonylContact O-C 3.51Å; R697-L700 PolarHBondContact O-N 2.94Å; R697-A701 WeakPolarHBondContact O-CB 3.47Å; R697-A701 PolarHBondContact O-N 3.04Å
698L68.6Low68.4Low104 Ų104117 Ų11755%0.54562%0.623SS.*Hα-helixtrans-64.5-40.9175.6-101.3110000111.8L694 L700 A701 L702L694-L698 WeakPolarHBondContact O-CB 3.49Å; L694-L698 WeakPolarHBondContact O-CD1 3.42Å; L694-L698 PolarHBondContact O-N 2.84Å; L698-L700 VanDerWaalsContact C-N 3.31Å; L698-L700 PolarHBondContact O-N 3Å; L698-A701 PolarHBondContact O-N 2.67Å; L698-L702 HydrophobicContact CD2-CD1 4.33Å; L698-L702 WeakPolarHBondContact O-CB 3.49Å; L698-L702 PolarHBondContact O-N 3.2Å
699K68.9Low65.7Low153 Ų153121 Ų12167%0.66564%0.636SS**Hα-helixtrans-62.8-36.2171.6-82-165.5171.1-1630112.6R695 R696 A701 G703R695-K699 WeakPolarHBondContact O-CB 3.46Å; R695-K699 WeakPolarHBondContact O-CG 3.33Å; R695-K699 PolarHBondContact O-N 3.48Å; R696-K699 PolarHBondContact O-N 3.04Å; K699-A701 VanDerWaalsContact C-N 3.35Å; K699-G703 WeakPolarHBondContact O-CA 3.4Å; K699-G703 PolarHBondContact O-N 3.44Å
700L65.6Low63.2Low120 Ų120123 Ų12363%0.62865%0.65SS**Hα-helixtrans-73.4-22.8174.8-78.6161.7000113.7R696 R697 L698 K704R696-L700 WeakPolarHBondContact O-CB 3.27Å; R696-L700 WeakPolarHBondContact O-CG 3.29Å; R696-L700 PolarHBondContact O-N 3.32Å; R697-L700 CarbonylContact O-C 3.51Å; R697-L700 PolarHBondContact O-N 2.94Å; L698-L700 VanDerWaalsContact C-N 3.31Å; L698-L700 PolarHBondContact O-N 3Å; L700-K704 WeakPolarHBondContact O-CG 3.49Å
701A60.8Low60.5Low64 Ų64129.1 Ų129.153%0.52968%0.676SS.*Hα-helixtrans-84.4-49173.800000111.7R697 L698 K699 G703 K704 G705R697-A701 WeakPolarHBondContact O-CB 3.47Å; R697-A701 PolarHBondContact O-N 3.04Å; L698-A701 PolarHBondContact O-N 2.67Å; K699-A701 VanDerWaalsContact C-N 3.35Å; A701-G703 VanDerWaalsContact C-N 3.33Å; A701-G703 PolarHBondContact O-N 3.02Å; A701-K704 PolarHBondContact O-N 3.46Å; A701-G705 PolarHBondContact O-N 3.03Å
702L55.8Low57.9Low116 Ų116135.7 Ų135.761%0.60770%0.697SS**Hα-helixtrans-64.2-36.8175.3-76159.8000111.8L698 K704 G705L698-L702 HydrophobicContact CD2-CD1 4.33Å; L698-L702 WeakPolarHBondContact O-CB 3.49Å; L698-L702 PolarHBondContact O-N 3.2Å; L702-K704 PolarHBondContact O-N 3.07Å; L702-K704 VanDerWaalsContact O-N 3.08Å; L702-G705 PolarHBondContact O-N 3.3Å
703G54.4Low55.1Low68 Ų68136.2 Ų136.270%0.70171%0.708SS**THydrogen-bonded Turntrans-68.22.8170.900000115K699 A701K699-G703 WeakPolarHBondContact O-CA 3.4Å; K699-G703 PolarHBondContact O-N 3.44Å; A701-G703 VanDerWaalsContact C-N 3.33Å; A701-G703 PolarHBondContact O-N 3.02Å
704K49Very low52.4Low190 Ų190135 Ų13583%0.82672%0.715SS**THydrogen-bonded Turntrans-119.810.2168.8-70.4-173.9173.8-168.30112.7L700 A701 L702L700-K704 WeakPolarHBondContact O-CG 3.49Å; A701-K704 PolarHBondContact O-N 3.46Å; L702-K704 PolarHBondContact O-N 3.07Å; L702-K704 VanDerWaalsContact O-N 3.08Å
705G50.3Low49.9Very low64 Ų64138 Ų13866%0.6673%0.731SS**SBendtrans-134.634.4-171.500000114A701 L702A701-G705 PolarHBondContact O-N 3.03Å; L702-G705 PolarHBondContact O-N 3.3Å
706A41.5Very low47.5Very low91 Ų91136.2 Ų136.275%0.75274%0.739SS**  trans-151.262.7-178.800000112.4
707D36.2Very low44.9Very low164 Ų164137.3 Ų137.388%0.87775%0.745SS**  trans-142.486.3166.3-139.1-20.3000110.2
708M37.8Very low43.4Very low181 Ų181134.2 Ų134.289%0.89275%0.745SS**  trans-125.387.5-178.9-168.8168.975.600110.5
709K33.4Very low41.7Very low193 Ų193136.3 Ų136.384%0.83976%0.755SS**  trans37.6109.3160-64.1-173.7177.6-175.90118
710P37.4Very low39.8Very low123 Ų123135.2 Ų135.280%0.79976%0.762SS**PPolyproline II helixtrans-69.4166.4155.633-34.7000111.5
711L31.5Very low38.1Very low174 Ų174137.1 Ų137.191%0.91177%0.772SS**PPolyproline II helixtrans-76.4165.4176.4-132.875.7000112.5
712E32.3Very low38Very low192 Ų192139.1 Ų139.190%0.89778%0.779SS**PPolyproline II helixtrans-71149.8-175-58.7172.899.800114.4
713S28.2Very low36.7Very low102 Ų102143.5 Ų143.571%0.71379%0.794SS**  -162.8125.2126.8-165.20000113.8
714T28.2Very low35.7Very low109 Ų109149.1 Ų149.167%0.66980%0.802SS**  trans55106.714454.90000122.8
715L29.9Very low36.3Very low161 Ų161145 Ų14584%0.84379%0.794SS**  90.1138.5114-77.9167000123.8
716V29.4Very low37Very low136 Ų136146.7 Ų146.782%0.82479%0.794SS**  trans89.7141.8161.9-161.10000118.7
717Y25.1Very low36.5Very low218 Ų218148.7 Ų148.786%0.85580%0.796SS**  trans-134.5-174.2-162.9-102.9-64.1000108.2
718P48.2Very low36.1Very low95 Ų95149.4 Ų149.462%0.61779%0.792SS**  cis-138.8-157.1-20.429.5-3.8000113.4
719I31.5Very low36.1Very low148 Ų148146.2 Ų146.276%0.75978%0.782SS**  trans79.6131.4154-65.9169000117.8
720T29.5Very low36.8Very low130 Ų130142.8 Ų142.880%0.79878%0.78SS**  cis-157.1160-15.925.40000112.8
721L30.3Very low36.6Very low161 Ų161142 Ų14284%0.84378%0.777SS**  trans-77.9-171.5164.1-83.1157.2000113
722P58.8Low36.4Very low105 Ų105142.7 Ų142.768%0.68277%0.773SS**  cis-136-171.6-34.135-16.7000113.3
723K28.6Very low36.4Very low209 Ų209141.4 Ų141.491%0.90977%0.769SS**  -166172.2117.9-107.9174.7-178.1-179.20114.7
724E32.8Very low37.3Very low186 Ų186141.5 Ų141.587%0.86977%0.767SS**  trans-139.4-174.1-149.9-110.1-152.3132.300113.7
725P60.9Low37.4Very low103 Ų103141.4 Ų141.467%0.66977%0.771SS**  trans-111.7-124.5-153.832.7-10.2000111.8
726P64.7Low37.6Very low100 Ų100141 Ų14165%0.64977%0.77SS**  cis-136-178-30.636.6-17.2000116
727T31.5Very low37.8Very low132 Ų132143.4 Ų143.481%0.8177%0.772SS**  172.2123.5129.629.20000110.3
728F29Very low38.1Very low179 Ų179139 Ų13979%0.78576%0.763SS**  66.911978.4-99.6-104.1000115.2
729V36.3Very low37.3Very low114 Ų114144.4 Ų144.469%0.69177%0.771SS**  cis80114.634-177.10000113
730P49.9Very low37Very low122 Ų122145.9 Ų145.979%0.79277%0.772SS**  -140.2174.292.828.1-7.9000113
731S31.5Very low37Very low105 Ų105150.7 Ų150.773%0.73478%0.776SS**  cis-155.3-160-11.348.70000106.9
732K28.3Very low36.9Very low189 Ų189150.2 Ų150.282%0.82277%0.769SS**  cis-160-176.411.6-149174.8177.2179.40110.3
733M32Very low35.4Very low166 Ų166152 Ų15282%0.81878%0.779SS**  trans-144.1-175.8-177.2-76.7-77-85.700108.3
734P47.4Very low35.3Very low104 Ų104145.6 Ų145.668%0.67577%0.772SS**  cis-148.4-170.113.845.7-25.5000119
735S30.7Very low35.2Very low106 Ų106140.9 Ų140.974%0.74177%0.765SS**  trans104.7143.9138.7660000121.4
736D33Very low33.8Very low153 Ų153142 Ų14282%0.81877%0.765SS**  trans-121.5157-169.9-51.9-90.8000111.8
737E35Very low32.1Very low186 Ų186146 Ų14687%0.86977%0.769SS**  160.9128.1115.7-81.8-145.4143.200114.9
738D31.6Very low32.1Very low125 Ų125148.3 Ų148.367%0.66876%0.764SS**  trans43.1133.8142.6-105.131.8000126.1
739R29.4Very low32.2Very low209 Ų209148.8 Ų148.879%0.78976%0.762SS**  trans93.8117.6137.2-76.7168.6-171.2-131.4-2.9124.1
740F26.8Very low31.9Very low180 Ų180148.3 Ų148.379%0.78976%0.763SS**  51.4116.9128.6-95.8-100.3000120.7
741W29.7Very low31Very low231 Ų231150 Ų15088%0.87577%0.766SS**  -160.6178.3114.1-95.3112.4000110
742E27.3Very low31Very low150 Ų150148.8 Ų148.870%0.70177%0.77SS**  trans-94170.8-168.5-58179.2110.300114.7
743T27.9Very low31.1Very low144 Ų144145.7 Ų145.788%0.88377%0.772SS**  trans69.2135.1161.365.30000120.1
744G26.6Very low31Very low74 Ų74145.2 Ų145.276%0.76377%0.772SS**  trans116.982.4138.400000120.3
745A30.5Very low30.2Very low87 Ų87150.2 Ų150.272%0.71978%0.783SS**  trans66.4137.4141.400000123.1
746N30.3Very low30.1Very low127 Ų127152 Ų15268%0.67978%0.783SS**  trans72.3150.4155.5-55.6-15.3000117.4
747Y29.6Very low29.8Very low184 Ų184151.2 Ų151.272%0.72278%0.783SS**  cis-149.6150.419.7-101.1-62.9000113.9
748Y31.1Very low29.7Very low179 Ų179147.7 Ų147.770%0.70278%0.777SS**  trans57.7155.8153.4-73.7-63.3000120.4
749Y30.9Very low29.5Very low190 Ų190145.4 Ų145.475%0.74578%0.782SS**  cis-134.7118.6-2.5-103.3-76.4000107.6
750S30.9Very low29.4Very low103 Ų103144.6 Ų144.672%0.7279%0.787SS**  79.9110.997.779.20000118.7
751D31Very low29.5Very low158 Ų158140.7 Ų140.785%0.84579%0.788SS**  trans-112.810916256.7-41000110.6S753D751-S753 PolarHBondContact O-N 2.82Å
752G30.7Very low29.5Very low80 Ų80138.1 Ų138.183%0.82579%0.791SS**  trans-85.398-171.800000113.8
753S31.3Very low29.6Very low123 Ų123134.7 Ų134.786%0.8680%0.795SS**  trans-152104.1167.6-80.90000112.4D751D751-S753 PolarHBondContact O-N 2.82Å
754L30.2Very low30.2Very low157 Ų157134.3 Ų134.382%0.82280%0.795SS**  trans-119.7110-170-130.8168000111.5I756L754-I756 HydrophobicContact CD2-CG1 4.08Å
755K28.8Very low30.4Very low208 Ų208136.2 Ų136.290%0.90480%0.797SS**  trans-81.9140.7162.8-84-178173.4178.30109.3
756I30Very low30.4Very low144 Ų144137.3 Ų137.374%0.73880%0.799SS**  trans-121.5131.4170.3-60.6178.5000109.5L754L754-I756 HydrophobicContact CD2-CG1 4.08Å
757V27Very low30.4Very low136 Ų136137.5 Ų137.582%0.82480%0.804SS**  trans-131.5134.2162.5178.40000105.8
758P32Very low30.4Very low113 Ų113134 Ų13473%0.73481%0.807SS**  trans-87.7151-159.733.2-36.7000115.2
759G26.9Very low30.4Very low76 Ų76130 Ų13078%0.78481%0.806SS**  trans-117.4153.4168.300000112.1
760H28.8Very low30.3Very low192 Ų192127.2 Ų127.289%0.88981%0.808SS**  trans-97.9148.6-174-68.135.5000113.4
761A28.3Very low30.2Very low98 Ų98127.2 Ų127.281%0.8182%0.815SS**  trans-162.995.1150.100000114.4
762L30.1Very low30.2Very low178 Ų178125 Ų12593%0.93281%0.811SS**  trans30.5111.1139.7-59.3170.9000123
763G29Very low30.8Very low77 Ų77126.5 Ų126.579%0.79481%0.806SS**  trans81.5165.7130.300000119.9
764P39.8Very low30.8Very low137 Ų137125.8 Ų125.889%0.8980%0.802SS**  cis-110.7-168.76.341.3-32000115
765S31.2Very low30.7Very low113 Ų113122.2 Ų122.279%0.7979%0.794SS**  trans-93.5149-162.454.40000117.7
766S31.1Very low30.8Very low110 Ų110120 Ų12077%0.76979%0.791SS**  -172.6118.3126.356.50000116.1
767V30.7Very low31Very low131 Ų131119 Ų11979%0.79479%0.794SS**  trans49.9119.1130.2-170.10000122.4
768S29.8Very low31.1Very low110 Ų110116.3 Ų116.377%0.76979%0.793SS**  trans67.7165.4149.877.70000119.3
769S30.4Very low31.1Very low97 Ų97119.4 Ų119.468%0.67880%0.798SS**  cis-168.7143.7-35.553.20000110.9
770T28.8Very low31.4Very low131 Ų131121.4 Ų121.480%0.80480%0.797SS**  trans50.2132.5153.453.40000122.7
771A29.5Very low31.3Very low103 Ų103118 Ų11885%0.85178%0.784SS**  trans85.6137.7144.800000121.7
772S30.6Very low31.2Very low110 Ų110121.8 Ų121.877%0.76979%0.785SS**  trans-72.8174.5159.2-32.20000110.6
773P43.1Very low31Very low112 Ų112118.3 Ų118.373%0.72778%0.775SS**  cis-149.2-171.123.943.5-21.7000118.4
774S31.4Very low31Very low109 Ų109121 Ų12176%0.76278%0.779SS**  trans81.5111.4146.3-62.90000123.7
775A27.4Very low30.5Very low81 Ų81120.4 Ų120.467%0.66978%0.778SS**  92.7114.1121.600000124.4
776I30Very low30.4Very low161 Ų161126.9 Ų126.983%0.82679%0.785SS**  63.3142.2121.1-60.6170.4000119.5
777P35.8Very low30.2Very low124 Ų124129.6 Ų129.681%0.80579%0.79SS**  cis-130.2176.4-1937.3-20.1000115.1
778G29Very low30Very low79 Ų79128 Ų12881%0.81479%0.785SS**  trans162.6107.8160.300000116
779Q31.2Very low30Very low179 Ų179130.5 Ų130.584%0.83679%0.789SS**  trans-119.1147.9171.6-102.7-173.4-5.800109.4
780P34.2Very low29.8Very low118 Ų118131.2 Ų131.277%0.76679%0.789SS**  -145.6-179.872.832.1-9.9000115
781I26.1Very low29.8Very low119 Ų119132.3 Ų132.361%0.6179%0.79SS**  cis-163.6152.6-27.8-101.2166.3000107.6
782H25.3Very low29.8Very low179 Ų179135.4 Ų135.483%0.82979%0.791SS**  trans63.3148.3171.5-64.7-34.9000118.5
783S26Very low29.7Very low104 Ų104140.9 Ų140.973%0.72779%0.794SS**  cis-161.2132.3-2045.90000110.6
784P29.8Very low28.9Very low134 Ų134138.9 Ų138.987%0.8779%0.794SS**  trans-104146.4-179.137-32.3000114.1
785S28.5Very low28.9Very low124 Ų124138.7 Ų138.787%0.86779%0.793SS**  trans-125.365.7179.452.60000114
786R29.6Very low29.2Very low250 Ų250138.1 Ų138.194%0.94380%0.795SS**  trans-145.3110.3158.5-100-170.4178.4-165.3-0.2110.5
787L26.8Very low29.2Very low166 Ų166136.1 Ų136.187%0.86980%0.795SS**  trans-87121168.2-88.4162.7000109.4
788S26.3Very low29.3Very low98 Ų98138.7 Ų138.769%0.68580%0.802SS**  trans-94127.9162.8-173.90000108.1
789L30.3Very low29.2Very low163 Ų163138.2 Ų138.285%0.85380%0.797SS**  trans-112.878176.4-73.7174.2000110
790T25.8Very low29Very low111 Ų111140.7 Ų140.768%0.68180%0.801SS**  trans-88.3146.7158.1420000109.7
791N29.9Very low28.8Very low154 Ų154142.6 Ų142.682%0.82480%0.803SS**  trans64.3101-180-56.6-27.9000116.5
792I28.7Very low28.8Very low169 Ų169148 Ų14887%0.86782%0.816SS**  -157.1122.4120.4-94.9145.9000107.6
793R28.8Very low28.8Very low224 Ų224147 Ų14785%0.84582%0.815SS**  trans-94.5125.5158.4-85.7-175173-177.6-2.8106.8
794G26.7Very low28.9Very low71 Ų71149.6 Ų149.673%0.73282%0.821SS**  trans-171.5122.9176.600000109.8
795S31.3Very low28.7Very low105 Ų105151.5 Ų151.573%0.73482%0.823SS**  trans-92.6147.6-168.8-169.60000113.4
796G34.1Very low28.6Very low69 Ų69151.2 Ų151.271%0.71182%0.821SS**  trans80.480.1137.300000118.8
797S29.7Very low28.7Very low119 Ų119146.2 Ų146.283%0.83282%0.818SS**  trans-157.2149.7142.752.40000111.9
798N36.5Very low28.8Very low178 Ų178143.5 Ų143.595%0.95282%0.82SS**  trans-75.8124.3171.4-69.9-33.2000109.2
799G27.2Very low28.9Very low69 Ų69142.2 Ų142.271%0.71182%0.822SS**  trans-151.5108.4-178.900000114
800Y28.3Very low28.8Very low230 Ų230143.3 Ų143.390%0.90282%0.823SS**  trans-66.6140.2153.6-77-98.7000108.5R802Y800-R802 PolarHBondContact O-N 3.14Å
801I28.5Very low29Very low158 Ų158144.6 Ų144.681%0.8182%0.821SS**  trans-70.197.6178.1-58176.5000109.5L803I801-L803 HydrophobicContact CG2-CD2 4.46Å; I801-L803 HydrophobicContact CG2-CG 4.47Å
802R26.6Very low28.9Very low234 Ų234147.3 Ų147.388%0.88382%0.82SS**  trans-88.9110.9159.3-84.7-175.3167.9172.5-3.4108.7Y800 N804Y800-R802 PolarHBondContact O-N 3.14Å; R802-N804 PolarHBondContact O-N 2.92Å
803L25.5Very low28.9Very low157 Ų157144.4 Ų144.482%0.82282%0.821SS**  trans-68.9124.1164.5-67.1170.2000108.8I801I801-L803 HydrophobicContact CG2-CD2 4.46Å; I801-L803 HydrophobicContact CG2-CG 4.47Å
804N27.4Very low29Very low159 Ų159139.7 Ų139.785%0.8582%0.822SS**  trans-148.7134.4163.4-118.4-2.2000108R802R802-N804 PolarHBondContact O-N 2.92Å
805L27.1Very low29.2Very low173 Ų173140.3 Ų140.391%0.90683%0.829SS**PPolyproline II helixtrans-79.8139.1-176.5-68.286.8000110.6
806S26.3Very low29.1Very low119 Ų119140.6 Ų140.683%0.83284%0.837SS**PPolyproline II helixtrans-87.1122.5170.854.90000111.2
807T30.1Very low28.9Very low144 Ų144140.6 Ų140.688%0.88384%0.837SS**PPolyproline II helixtrans-94133.6156.748.30000109.1
808A28.9Very low29Very low110 Ų110142.6 Ų142.691%0.90985%0.845SS**PPolyproline II helixtrans-84.6161.9-174.400000113.3
809G29.2Very low28.7Very low70 Ų70137.7 Ų137.772%0.72284%0.836SS**  trans-173.5132.2172.100000111.7
810E29.3Very low28.9Very low186 Ų186138.4 Ų138.487%0.86984%0.843SS**  trans-69.8169.3179-66.9131.5118.500113.3
811E28.3Very low29Very low138 Ų138131.6 Ų131.665%0.64584%0.843SS**  cis-154.9177.9-13-124.5-152.1131.600111.1
812R28.4Very low29Very low211 Ų211127.8 Ų127.880%0.79684%0.842SS**  trans-7.6127.3159.6-64.5169.2164128.6-10.8119
813A29.3Very low29.2Very low108 Ų108125.4 Ų125.489%0.89385%0.846SS**  -158.9148.9129.900000112.1
814S30.3Very low29.4Very low125 Ų125122 Ų12287%0.87485%0.85SS**  trans-105.9139.2174.656.20000111.4
815G30.3Very low29.5Very low84 Ų84117.8 Ų117.887%0.86684%0.843SS**  trans163.7130.6166.700000113.6
816A31Very low29.6Very low111 Ų111118.7 Ų118.792%0.91785%0.848SS**  trans-119.4139170.200000109.4
817G29.9Very low29.7Very low69 Ų69116.5 Ų116.571%0.71184%0.844SS**  trans149.611016400000116.8
818V31.7Very low29.7Very low162 Ų162117 Ų11798%0.98285%0.847SS**  trans63.2129.2141.8-169.40000119.4
819G29.9Very low29.7Very low75 Ų75115.3 Ų115.377%0.77384%0.84SS**  trans153.6104.2151.700000116.9
820G30.5Very low29.6Very low84 Ų84115.6 Ų115.687%0.86684%0.843SS**  trans-64.8152-173.700000119.7
821G29.7Very low29.6Very low87 Ų87115 Ų11590%0.89785%0.845SS**  81.5143.8129.100000120.8
822G29.9Very low29.8Very low77 Ų77114.7 Ų114.779%0.79485%0.849SS**  trans14191.7157.300000118.8
823L29.9Very low30Very low185 Ų185116 Ų11697%0.96986%0.855SS**  trans11.9132.7145-67.4158.6000122.5
824G30.3Very low30.4Very low86 Ų86115.1 Ų115.189%0.88784%0.842SS**  trans90.1156.8151.800000117.3
825G29.4Very low30.9Very low70 Ų70113 Ų11372%0.72283%0.827SS**  cis162122.3-13.400000114.9
826L29.8Very low31.4Very low192 Ų192114.7 Ų114.7100%1.00582%0.823SS**  trans63.9149.9166.6-60.6166.4000119.2
827G28.3Very low31.8Very low73 Ų73117.7 Ų117.775%0.75382%0.816SS**  trans140.364152.400000122
828V29.9Very low32.3Very low155 Ų155121.1 Ų121.194%0.93981%0.811SS**  trans18.8132.6140.7-176.70000121.5
829G27.6Very low33Very low73 Ų73118.6 Ų118.675%0.75379%0.789SS**  135.299.8123.700000122.4
830G27.9Very low33.9Very low77 Ų77120.2 Ų120.279%0.79478%0.776SS**  trans82154.415200000117.9
831N30Very low34.4Very low172 Ų172121.2 Ų121.292%0.9276%0.761SS**  cis-149159.1-2.8-132.213.4000111.3
832D32.7Very low35Very low133 Ų133124.5 Ų124.571%0.71175%0.746SS**  trans-74.9151.8-174.6-91.3-66.9000115.6
833Y31.5Very low35.7Very low239 Ų239128.8 Ų128.894%0.93774%0.738SS**  trans-141.999.2142.2-102.8-79.3000109.5
834S37.2Very low36.4Very low89 Ų89124 Ų12462%0.62272%0.717SS**  trans-84.4132.5-178.254.90000112.6
835S41.8Very low36.9Very low80 Ų80126.4 Ų126.456%0.55971%0.709SS**  trans-87155.9173.974.60000112.8F837S835-F837 PolarHBondContact O-N 3.45Å
836P41.2Very low37.5Very low119 Ų119130.9 Ų130.977%0.77371%0.711SS**THydrogen-bonded Turntrans-64.7-11.4-170.2-2435.2000116.2K838P836-K838 VanDerWaalsContact C-N 3.26Å; P836-K838 PolarHBondContact O-N 3.5Å
837F38.5Very low38.1Very low174 Ų174129.6 Ų129.676%0.76370%0.7SS**Hα-helixtrans-72.5-17-172.9-153.8-100.2000113.7S835S835-F837 PolarHBondContact O-N 3.45Å
838K41Very low38.4Very low141 Ų141137.7 Ų137.761%0.61371%0.708SS**Hα-helixtrans-80.9-31.8-173.4-149.7172.8-174.2177.80113.2P836 R842P836-K838 VanDerWaalsContact C-N 3.26Å; P836-K838 PolarHBondContact O-N 3.5Å; K838-R842 PolarHBondContact O-N 2.88Å
839E47.1Very low38.6Very low110 Ų110135.9 Ų135.951%0.51470%0.702SS.*Hα-helixtrans-74.5-41.2179.7-107.846.3-123.700112.3L841 R842 R843E839-L841 VanDerWaalsContact C-N 3.34Å; E839-L841 PolarHBondContact O-N 3.47Å; E839-R842 WeakPolarHBondContact O-CA 3.32Å; E839-R842 VanDerWaalsContact O-CB 3.31Å; E839-R842 WeakPolarHBondContact O-CB 3.5Å; E839-R842 PolarHBondContact O-N 3.39Å; E839-R842 VanDerWaalsContact O-N 3.07Å; E839-R843 PolarHBondContact O-N 3.21Å
840E46.9Very low39Very low108 Ų108139 Ų13951%0.50571%0.706SS.*Hα-helixtrans-67.3-35.6-179-160.258.1-143.700112R842 R843 T844E840-R842 VanDerWaalsContact C-N 3.31Å; E840-R842 PolarHBondContact O-N 3.37Å; E840-R843 PolarHBondContact O-N 3.38Å; E840-T844 PolarHBondContact O-N 2.93Å; E840-T844 VanDerWaalsContact O-N 3.13Å; E840-T844 PolarHBondContact O-OG1 3.13Å
841L41Very low39.2Very low105 Ų105142.9 Ų142.955%0.5571%0.708SS.*Hα-helixtrans-67-32.4172-168.967.4000112.1E839 T844 L845E839-L841 VanDerWaalsContact C-N 3.34Å; E839-L841 PolarHBondContact O-N 3.47Å; L841-T844 WeakPolarHBondContact CA-OG1 3.44Å; L841-T844 PolarHBondContact O-OG1 3.49Å; L841-L845 HydrophobicContact CG-CD1 4.46Å; L841-L845 WeakPolarHBondContact O-CD1 3.49Å; L841-L845 WeakPolarHBondContact O-CG 3.31Å; L841-L845 PolarHBondContact O-N 3.43Å
842R43.8Very low39.3Very low157 Ų157140 Ų14059%0.59270%0.699SS**Hα-helixtrans-69.4-42.5173.9-120.1180-176.1139.51.3111.8K838 E839 E840 L845 Q846K838-R842 PolarHBondContact O-N 2.88Å; E839-R842 WeakPolarHBondContact O-CA 3.32Å; E839-R842 VanDerWaalsContact O-CB 3.31Å; E839-R842 WeakPolarHBondContact O-CB 3.5Å; E839-R842 PolarHBondContact O-N 3.39Å; E839-R842 VanDerWaalsContact O-N 3.07Å; E840-R842 VanDerWaalsContact C-N 3.31Å; E840-R842 PolarHBondContact O-N 3.37Å; R842-L845 PolarHBondContact O-N 3.07Å; R842-Q846 PolarHBondContact O-N 3.34Å
843R43.6Very low39.7Very low166 Ų166141.9 Ų141.963%0.62671%0.709SS**Hα-helixtrans-63.7-41.2-179.1-166.6-179.9-171179.72.8112.4E839 E840E839-R843 PolarHBondContact O-N 3.21Å; E840-R843 PolarHBondContact O-N 3.38Å
844T44.3Very low39.5Very low86 Ų86135 Ų13553%0.52870%0.701SS.*Hα-helixtrans-71.4-30.3177.940.40000113.5E840 L841 Q846E840-T844 PolarHBondContact O-N 2.93Å; E840-T844 VanDerWaalsContact O-N 3.13Å; E840-T844 PolarHBondContact O-OG1 3.13Å; L841-T844 WeakPolarHBondContact CA-OG1 3.44Å; L841-T844 PolarHBondContact O-OG1 3.49Å; T844-Q846 VanDerWaalsContact C-N 3.34Å; T844-Q846 PolarHBondContact O-N 3.32Å
845L40.6Very low39.2Very low136 Ų136137.7 Ų137.771%0.71271%0.708SS**Hα-helixtrans-75.7-15.2178-74.7170.6000114.6L841 R842L841-L845 HydrophobicContact CG-CD1 4.46Å; L841-L845 WeakPolarHBondContact O-CD1 3.49Å; L841-L845 WeakPolarHBondContact O-CG 3.31Å; L841-L845 PolarHBondContact O-N 3.43Å; R842-L845 PolarHBondContact O-N 3.07Å
846Q41.8Very low38.8Very low163 Ų163139.5 Ų139.576%0.76272%0.718SS**THydrogen-bonded Turntrans-91.10.4-178.8-72.7-176.5-28.700114.8R842 T844R842-Q846 PolarHBondContact O-N 3.34Å; T844-Q846 VanDerWaalsContact C-N 3.34Å; T844-Q846 PolarHBondContact O-N 3.32Å
847Q43.3Very low38.4Very low166 Ų166142.7 Ų142.778%0.77672%0.723SS**  trans-107.321.8-172.1-69.8-164.4-3600115.9
848R34.2Very low38.2Very low243 Ų243143.6 Ų143.692%0.91773%0.73SS**  trans-110.1124.7169.5-86-174.1168.1-179.4-3.9112.1
849S33.9Very low37.5Very low117 Ų117142.6 Ų142.682%0.81874%0.74SS**  trans-75.3157.1172.544.30000112.1
850V36Very low36.6Very low139 Ų139143.2 Ų143.284%0.84276%0.757SS**  trans-83.9139.9177.5-179.30000110.3
851L32.3Very low35.9Very low157 Ų157148.7 Ų148.782%0.82280%0.797SS**  trans-125.3149.2162.3-80.1170.2000108.7
852P32.7Very low35.7Very low113 Ų113150.9 Ų150.973%0.73481%0.809SS**  trans-80.2171.8-166.233-37.3000114.4
853D40.3Very low35.2Very low172 Ų172150.5 Ų150.592%0.9282%0.821SS**  trans-53.6137.9-166.5-57.6-77.7000116.3
854A28.7Very low34.8Very low94 Ų94149.7 Ų149.778%0.77783%0.832SS**  trans-131142.716600000110.1
855N29.3Very low34.2Very low145 Ų145153.4 Ų153.478%0.77585%0.85SS**  trans-76.8132.2-165.2-161.736.8000112.7E857N855-E857 PolarHBondContact O-N 2.99Å
856P33.3Very low33.8Very low118 Ų118154.5 Ų154.577%0.76686%0.858SS**SBendtrans-87.864.3-167.636.1-38000114.5
857E33.2Very low33.3Very low187 Ų187153.9 Ų153.987%0.87487%0.865SS**SBendtrans-126.315.1168-76-151.9135.300114.5N855N855-E857 PolarHBondContact O-N 2.99Å
858E34.3Very low32.6Very low192 Ų192153.1 Ų153.190%0.89787%0.871SS**SBendtrans-141.553.9-175.2-148.3168.7-12700115.5
859S27.6Very low32.4Very low120 Ų120146.2 Ų146.284%0.83987%0.867SS**  trans-153.697.5166.169.50000115.7
860S27.4Very low32.3Very low123 Ų123148.6 Ų148.686%0.8687%0.872SS**  trans-158.4105.9149.7630000110
861V32.8Very low32Very low223 Ų223149.5 Ų149.5100%1.35287%0.874SS**  trans-109.40167.3177.30000107.3

Retrieved 861 of 861 residues in 557.3 ms (Link to these results)