A0A087X7R3_POEFO Loading...

Pyrimidinergic receptor P2Y6

AlphaFold DB , UniProt , Accession A0A087X7R3, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 361 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37	Very low	31.3	Very low	248 Å²	248	160.6 Å²	160.6	100%	1.222	85%	0.85	S	S	*	*				0	94.4	0	-163.3	170.3	172.9	0	0	107.5
2	Q	29.4	Very low	31.3	Very low	174 Å²	174	156 Å²	156	81%	0.813	84%	0.84	S	S	*	*			trans	-73	140.2	170.9	-79.3	153.5	-55.9	0	0	109.3
3	H	26.5	Very low	31.1	Very low	177 Å²	177	156.2 Å²	156.2	82%	0.819	84%	0.839	S	S	*	*				178.7	150.5	105.5	-107.7	-83.8	0	0	0	113.1
4	F	30.1	Very low	31	Very low	192 Å²	192	156.6 Å²	156.6	84%	0.842	84%	0.839	S	S	*	*			trans	-87.5	177.7	-171	-109.1	-97.2	0	0	0	115
5	L	33.6	Very low	30.7	Very low	140 Å²	140	153.8 Å²	153.8	73%	0.733	84%	0.836	S	S	*	*			trans	113.5	131.3	155.1	-61.7	160.9	0	0	0	112.6
6	N	27.3	Very low	30.9	Very low	146 Å²	146	160 Å²	160	78%	0.781	84%	0.843	S	S	*	*			cis	-163.5	153.4	12.3	-102.2	-26.2	0	0	0	110.9
7	S	27.2	Very low	30.8	Very low	111 Å²	111	155.8 Å²	155.8	78%	0.776	84%	0.837	S	S	*	*			trans	-67.6	178.5	166.5	-53.9	0	0	0	0	112.6
8	P	35.7	Very low	30.8	Very low	120 Å²	120	155.9 Å²	155.9	78%	0.779	84%	0.835	S	S	*	*			cis	-146	-166.8	25.4	46.5	-23.2	0	0	0	115.6
9	P	33.2	Very low	31.2	Very low	122 Å²	122	153.9 Å²	153.9	79%	0.792	83%	0.832	S	S	*	*			trans	-93.9	153.7	-165.4	37.4	-30.4	0	0	0	114.1
10	T	31.4	Very low	31	Very low	146 Å²	146	151.7 Å²	151.7	90%	0.896	83%	0.828	S	S	*	*			trans	-87.2	103.8	176.7	22.1	0	0	0	0	111.9
11	E	33	Very low	31	Very low	191 Å²	191	152.2 Å²	152.2	89%	0.893	83%	0.83	S	S	*	*			trans	-98.7	133.4	148.3	-79.6	-170.5	154	0	0	109
12	S	30.8	Very low	30.5	Very low	105 Å²	105	148.3 Å²	148.3	73%	0.734	81%	0.813	S	S	*	*			trans	-140.9	113.6	161	52.4	0	0	0	0	107.7
13	L	28.8	Very low	30.4	Very low	158 Å²	158	147 Å²	147	83%	0.827	81%	0.811	S	S	*	*				57.8	118.2	84.8	-74.5	152.7	0	0	0	110.9
14	I	29.9	Very low	30.5	Very low	163 Å²	163	144.5 Å²	144.5	84%	0.836	81%	0.814	S	S	*	*				-169.7	125.2	83.1	-76.2	146	0	0	0	109.2
15	S	26.3	Very low	30.3	Very low	114 Å²	114	140.2 Å²	140.2	80%	0.797	80%	0.804	S	S	*	*				-179.7	95.3	117.9	-159.9	0	0	0	0	110.2
16	R	34.3	Very low	30	Very low	253 Å²	253	141.6 Å²	141.6	96%	0.955	81%	0.806	S	S	*	*			trans	-86	132.6	154.8	-85.2	178.4	170	162.1	-3.2	107
17	A	29.9	Very low	29.9	Very low	88 Å²	88	143 Å²	143	73%	0.727	81%	0.812	S	S	*	*			trans	-165.2	141.8	144.3	0	0	0	0	0	111.6
18	I	29.8	Very low	29.8	Very low	158 Å²	158	146 Å²	146	81%	0.81	81%	0.814	S	S	*	*			trans	93.5	95.2	164	-45.7	164.3	0	0	0	117
19	P	39.1	Very low	29.3	Very low	119 Å²	119	145.7 Å²	145.7	77%	0.773	82%	0.815	S	S	*	*			trans	-103.2	140.9	152.5	34.8	-23.4	0	0	0	110.8
20	S	26.8	Very low	29.2	Very low	108 Å²	108	148.8 Å²	148.8	76%	0.755	82%	0.818	S	S	*	*			trans	-160.1	109.5	153.3	-46.7	0	0	0	0	109.6	L22	S20-L22 PolarHBondContact O-N 2.8Å
21	D	31.3	Very low	29.5	Very low	164 Å²	164	146.3 Å²	146.3	88%	0.877	81%	0.805	S	S	*	*			trans	-47.3	119	151.7	-61.8	-63	0	0	0	110
22	L	26.2	Very low	29.3	Very low	165 Å²	165	145.2 Å²	145.2	86%	0.864	81%	0.805	S	S	*	*			trans	-165	93.4	158.9	-144.9	80.5	0	0	0	109.2	S20	S20-L22 PolarHBondContact O-N 2.8Å
23	L	26.4	Very low	29.2	Very low	147 Å²	147	144 Å²	144	77%	0.77	81%	0.81	S	S	*	*				171	65.9	123.9	-158.6	72.5	0	0	0	110
24	S	28.6	Very low	29.2	Very low	124 Å²	124	142.4 Å²	142.4	87%	0.867	81%	0.806	S	S	*	*			trans	-85.3	106	152.5	17.5	0	0	0	0	107.7
25	T	26.9	Very low	29.2	Very low	103 Å²	103	144 Å²	144	63%	0.632	81%	0.81	S	S	*	*			trans	-133.1	108.8	158.2	38.4	0	0	0	0	109.2
26	H	26.9	Very low	29.5	Very low	168 Å²	168	145.2 Å²	145.2	78%	0.778	81%	0.806	S	S	*	*			trans	34	118.7	142.5	-71.8	-77.7	0	0	0	120
27	L	25.2	Very low	29.3	Very low	175 Å²	175	138.4 Å²	138.4	92%	0.916	80%	0.797	S	S	*	*				-164.2	112.1	121.6	-104.4	140.3	0	0	0	109.9
28	E	25.6	Very low	29.4	Very low	176 Å²	176	140.6 Å²	140.6	82%	0.822	80%	0.801	S	S	*	*			trans	-81.9	139.6	166.9	-74.3	175.1	135.2	0	0	110.3
29	S	25.9	Very low	29.5	Very low	113 Å²	113	135.7 Å²	135.7	79%	0.79	79%	0.789	S	S	*	*			trans	172.2	103.8	130.3	38.2	0	0	0	0	112.3
30	E	30.2	Very low	29	Very low	186 Å²	186	134.9 Å²	134.9	87%	0.869	79%	0.787	S	S	*	*			trans	52.9	159.6	135.6	-79.5	-91.4	122.6	0	0	122
31	P	38.6	Very low	29.6	Very low	95 Å²	95	139.4 Å²	139.4	62%	0.617	79%	0.793	S	S	*	*				-112.7	152.9	-120.2	40.2	-33.1	0	0	0	114.5
32	N	28.8	Very low	29.8	Very low	168 Å²	168	136.1 Å²	136.1	90%	0.898	78%	0.783	S	S	*	*			trans	-155.4	106.2	148.7	-104.7	-23.1	0	0	0	109.9	T34	N32-T34 PolarHBondContact O-N 3.34Å; N32-T34 VanDerWaalsContact O-N 3.11Å
33	G	26.9	Very low	30.4	Very low	80 Å²	80	136.5 Å²	136.5	83%	0.825	79%	0.786	S	S	*	*			trans	-73	97	-177.7	0	0	0	0	0	112.2
34	T	29.8	Very low	31.1	Very low	123 Å²	123	133.3 Å²	133.3	76%	0.755	78%	0.78	S	S	*	*			trans	-89.7	112	150.6	38.2	0	0	0	0	108.4	N32 I36	N32-T34 PolarHBondContact O-N 3.34Å; N32-T34 VanDerWaalsContact O-N 3.11Å; T34-I36 PolarHBondContact O-N 2.82Å
35	H	30.7	Very low	32.2	Very low	196 Å²	196	131.6 Å²	131.6	91%	0.907	77%	0.768	S	S	*	*			trans	-58	94	170.2	-85.2	-97.2	0	0	0	110.2	S37	H35-S37 PolarHBondContact O-N 3.3Å
36	I	31	Very low	33.7	Very low	141 Å²	141	133.7 Å²	133.7	72%	0.723	78%	0.775	S	S	*	*			trans	-84.8	97.3	160.7	-59.5	178.7	0	0	0	105.8	T34 V38	T34-I36 PolarHBondContact O-N 2.82Å; I36-V38 PolarHBondContact O-N 3.28Å
37	S	30.5	Very low	35.7	Very low	109 Å²	109	136.1 Å²	136.1	76%	0.762	78%	0.777	S	S	*	*			trans	-58.8	100.9	166.9	51.3	0	0	0	0	108.5	H35 G39	H35-S37 PolarHBondContact O-N 3.3Å; S37-G39 PolarHBondContact O-N 3.3Å
38	V	31.9	Very low	38.3	Very low	135 Å²	135	129.6 Å²	129.6	82%	0.818	75%	0.746	S	S	*	*			trans	-65	91.3	164	178.5	0	0	0	0	106.1	I36 S40	I36-V38 PolarHBondContact O-N 3.28Å; V38-S40 PolarHBondContact O-N 3.5Å; V38-S40 VanDerWaalsContact O-N 3.09Å
39	G	32.2	Very low	41	Very low	54 Å²	54	125.9 Å²	125.9	56%	0.557	74%	0.736	S	S	*	*			trans	-57.1	115.1	174	0	0	0	0	0	108.6	S37 F41	S37-G39 PolarHBondContact O-N 3.3Å; G39-F41 PolarHBondContact O-N 3.49Å
40	S	29.6	Very low	43.8	Very low	103 Å²	103	124 Å²	124	72%	0.72	71%	0.712	S	S	*	*			trans	-43.3	112.6	170.1	180	0	0	0	0	109.5	V38 S42	V38-S40 PolarHBondContact O-N 3.5Å; V38-S40 VanDerWaalsContact O-N 3.09Å; S40-S42 PolarHBondContact O-N 3.1Å
41	F	37.3	Very low	46.5	Very low	203 Å²	203	122.8 Å²	122.8	89%	0.89	70%	0.704	S	S	*	*			trans	-63	89.1	166.7	-93.5	-97	0	0	0	107.1	G39 N43	G39-F41 PolarHBondContact O-N 3.49Å; F41-N43 PolarHBondContact O-N 3.28Å
42	S	36.9	Very low	48.8	Very low	95 Å²	95	119.1 Å²	119.1	66%	0.664	68%	0.678	S	S	*	*			trans	-56.7	126.2	167.2	-60.9	0	0	0	0	106.9	S40 A44	S40-S42 PolarHBondContact O-N 3.1Å; S42-A44 PolarHBondContact O-N 2.96Å
43	N	37.9	Very low	51.7	Low	173 Å²	173	116 Å²	116	93%	0.925	66%	0.661	S	S	*	*			trans	-61.8	69.9	169.5	-87.8	-29.9	0	0	0	109.9	F41 S45	F41-N43 PolarHBondContact O-N 3.28Å; N43-S45 PolarHBondContact O-N 2.94Å; N43-S45 VanDerWaalsContact O-N 3.1Å
44	A	42.7	Very low	54.8	Low	79 Å²	79	115.2 Å²	115.2	65%	0.653	64%	0.636	S	S	*	*			trans	-69.1	105.8	165.2	0	0	0	0	0	105.6	S42 L46	S42-A44 PolarHBondContact O-N 2.96Å; A44-L46 PolarHBondContact O-N 3.16Å
45	S	49.9	Very low	57.8	Low	88 Å²	88	110.2 Å²	110.2	62%	0.615	60%	0.603	S	S	*	*			trans	-44.7	111	163.7	58.7	0	0	0	0	107.5	N43 R47	N43-S45 PolarHBondContact O-N 2.94Å; N43-S45 VanDerWaalsContact O-N 3.1Å; S45-R47 VanDerWaalsContact C-N 3.25Å; S45-R47 PolarHBondContact O-N 3.33Å
46	L	58.7	Low	60.7	Low	148 Å²	148	103.5 Å²	103.5	78%	0.775	57%	0.571	S	S	*	*			trans	-68.1	85.4	-172.3	-152.1	90	0	0	0	108.7	A44 C48	A44-L46 PolarHBondContact O-N 3.16Å; L46-C48 PolarHBondContact O-N 2.92Å
47	R	69.1	Low	63.7	Low	218 Å²	218	103.1 Å²	103.1	82%	0.823	57%	0.57	S	S	*	*			trans	-74.5	98.4	179.6	-75.5	-174.7	179	177	0.7	108.2	S45 T49	S45-R47 VanDerWaalsContact C-N 3.25Å; S45-R47 PolarHBondContact O-N 3.33Å; R47-T49 PolarHBondContact O-N 2.97Å
48	C	79.8	Confident	66.8	Low	38 Å²	38	100.9 Å²	100.9	26%	0.257	55%	0.549	S	S	.	.	P	Polyproline II helix	trans	-60.4	127.2	173.9	-60.5	0	0	0	0	110.7	L46 Y50 C305	L46-C48 PolarHBondContact O-N 2.92Å; C48-Y50 HydrophobicContact CB-CE2 4.31Å; C48-C305 WeakPolarHBondContact CA-SG 3.47Å; C48-C305 HydrophobicContact CB-CB 3.76Å; C48-C305 WeakPolarHBondContact CB-SG 3.43Å; C48-C305 VanDerWaalsContact SG-CA 3.52Å; C48-C305 WeakPolarHBondContact SG-CB 3.42Å; C48-C305 CovalentContact SG-SG 2.04Å; C48-C305 PolarHBondContact SG-SG 3.26Å
49	T	83.1	Confident	69.8	Low	99 Å²	99	94.6 Å²	94.6	61%	0.607	51%	0.51	S	S	*	.	P	Polyproline II helix	trans	-99.2	117.6	175.1	-63.5	0	0	0	0	109.8	R47	R47-T49 PolarHBondContact O-N 2.97Å
50	Y	84.9	Confident	72.9	Confident	73 Å²	73	92.5 Å²	92.5	29%	0.286	49%	0.487	S	S	.	.	P	Polyproline II helix	trans	-86.3	130.3	180	-65.2	-94.1	0	0	0	111.1	C48 E52 R308 N309 A312	C48-Y50 HydrophobicContact CB-CE2 4.31Å; Y50-E52 WeakPolarHBondContact CB-OE1 3.4Å; Y50-R308 HydrophobicContact CE1-CB 4.22Å; Y50-N309 VanDerWaalsContact CA-OD1 3.28Å; Y50-N309 WeakPolarHBondContact CA-OD1 3.23Å; Y50-N309 HydrophobicContact CD1-CB 4.27Å; Y50-A312 HydrophobicContact CD1-CB 3.66Å; Y50-A312 HydrophobicContact CE1-CB 3.7Å
51	K	86.3	Confident	76.1	Confident	161 Å²	161	90 Å²	90	70%	0.7	47%	0.473	S	S	*	.			trans	-96.6	87.7	178.1	-67.9	-177.7	-179.2	179	0	109.6	N309	K51-N309 PolarHBondContact N-OD1 2.95Å
52	E	86.8	Confident	78.9	Confident	17 Å²	17	81.8 Å²	81.8	8%	0.079	44%	0.439	C	S	.	.			trans	-123.3	23.2	-168.4	-57.2	178.6	166.4	0	0	113.5	Y50 F54 K55 K316	Y50-E52 WeakPolarHBondContact CB-OE1 3.4Å; E52-F54 HydrophobicContact CB-CE1 4.33Å; E52-F54 PolarHBondContact O-N 2.77Å; E52-K55 HydrophobicContact CB-CD 3.92Å; E52-K55 WeakPolarHBondContact O-CB 3.48Å; E52-K55 WeakPolarHBondContact O-CD 3.21Å; E52-K55 WeakPolarHBondContact O-CG 3.32Å; E52-K55 PolarHBondContact O-N 3.46Å; E52-K55 VanDerWaalsContact O-N 3.08Å; E52-K55 IonicContact OE2-NZ 3.18Å; E52-K55 PolarHBondContact OE2-NZ 2.88Å; E52-K316 HydrophobicContact CG-CD 4.43Å; E52-K316 IonicContact OE1-NZ 2.62Å; E52-K316 PolarHBondContact OE1-NZ 2.81Å; E52-K316 WeakPolarHBondContact OE2-CD 3.27Å; E52-K316 WeakPolarHBondContact OE2-CE 3.41Å; E52-K316 IonicContact OE2-NZ 2.9Å; E52-K316 PolarHBondContact OE2-NZ 2.97Å
53	D	89.3	Confident	81.8	Confident	102 Å²	102	77.3 Å²	77.3	55%	0.545	41%	0.408	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62	-28.5	-173.9	-65.6	-53.6	0	0	0	113.3	K55 K56	D53-K55 PolarHBondContact O-N 3.05Å; D53-K55 VanDerWaalsContact O-N 3.09Å; D53-K56 WeakPolarHBondContact O-CB 3.34Å; D53-K56 WeakPolarHBondContact O-CG 3.19Å; D53-K56 PolarHBondContact O-N 3.23Å; D53-K56 VanDerWaalsContact O-N 3.1Å; D53-K56 WeakPolarHBondContact OD1-CE 3.32Å; D53-K56 IonicContact OD1-NZ 2.65Å; D53-K56 PolarHBondContact OD1-NZ 2.94Å
54	F	91.9	Very high	84.7	Confident	65 Å²	65	72.9 Å²	72.9	29%	0.285	38%	0.383	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.8	-31.5	175.2	76.3	-86.2	0	0	0	112.8	E52 K56 I57 L58 I313 K316 S317	E52-F54 HydrophobicContact CB-CE1 4.33Å; E52-F54 PolarHBondContact O-N 2.77Å; F54-K56 PolarHBondContact O-N 3.09Å; F54-I57 PolarHBondContact O-N 3.43Å; F54-I57 VanDerWaalsContact O-N 3.13Å; F54-L58 HydrophobicContact CD2-CB 4.29Å; F54-L58 HydrophobicContact CD2-CD2 3.87Å; F54-L58 HydrophobicContact CE2-CD2 3.93Å; F54-L58 WeakPolarHBondContact O-CB 3.48Å; F54-L58 PolarHBondContact O-N 2.84Å; F54-I313 HydrophobicContact CE1-CB 4.21Å; F54-I313 HydrophobicContact CE1-CG1 4.01Å; F54-I313 HydrophobicContact CE1-CG2 3.82Å; F54-I313 HydrophobicContact CZ-CB 4.47Å; F54-I313 HydrophobicContact CZ-CG2 4.01Å; F54-K316 HydrophobicContact CZ-CB 3.96Å; F54-S317 VanDerWaalsContact CE2-OG 3.23Å; F54-S317 WeakPolarHBondContact CE2-OG 3.39Å; F54-S317 WeakPolarHBondContact CZ-OG 3.3Å
55	K	92.6	Very high	87.3	Confident	17 Å²	17	72.6 Å²	72.6	7%	0.074	37%	0.373	C	S	.	.	H	α-helix	trans	-65.8	-25.1	-175.7	89.6	-173.1	155.9	173.5	0	112.1	E52 D53 I57 L59 P60 Y116 D120 K316	E52-K55 HydrophobicContact CB-CD 3.92Å; E52-K55 WeakPolarHBondContact O-CB 3.48Å; E52-K55 WeakPolarHBondContact O-CD 3.21Å; E52-K55 WeakPolarHBondContact O-CG 3.32Å; E52-K55 PolarHBondContact O-N 3.46Å; E52-K55 VanDerWaalsContact O-N 3.08Å; E52-K55 IonicContact OE2-NZ 3.18Å; E52-K55 PolarHBondContact OE2-NZ 2.88Å; D53-K55 PolarHBondContact O-N 3.05Å; D53-K55 VanDerWaalsContact O-N 3.09Å; K55-I57 PolarHBondContact O-N 3.49Å; K55-L59 HydrophobicContact CB-CD1 3.67Å; K55-L59 HydrophobicContact CB-CG 4.43Å; K55-L59 HydrophobicContact CG-CD1 4.2Å; K55-L59 WeakPolarHBondContact O-CB 3.4Å; K55-L59 PolarHBondContact O-N 3.01Å; K55-L59 VanDerWaalsContact O-N 3.15Å; K55-P60 VanDerWaalsContact O-CD 3.28Å; K55-P60 WeakPolarHBondContact O-CD 3.46Å; K55-Y116 HydrophobicContact CD-CD1 4.39Å; K55-Y116 HydrophobicContact CD-CE1 4.46Å; K55-Y116 HydrophobicContact CG-CD1 4.27Å; K55-D120 VanDerWaalsContact CE-CG 3.46Å; K55-D120 WeakPolarHBondContact CE-OD1 3.44Å; K55-D120 WeakPolarHBondContact CE-OD2 3.44Å; K55-D120 VanDerWaalsContact NZ-CG 3.27Å; K55-D120 IonicContact NZ-OD1 2.65Å; K55-D120 PolarHBondContact NZ-OD1 3.46Å; K55-D120 IonicContact NZ-OD2 2.78Å; K55-D120 PolarHBondContact NZ-OD2 2.78Å; K55-K316 HydrophobicContact CD-CD 4Å
56	K	92.4	Very high	89.6	Confident	55 Å²	55	68.4 Å²	68.4	24%	0.239	34%	0.344	C	S	.	.	H	α-helix	trans	-67.5	-21.9	178	-58.8	169.1	180	169.4	0	112.7	D53 F54 P60 H119	D53-K56 WeakPolarHBondContact O-CB 3.34Å; D53-K56 WeakPolarHBondContact O-CG 3.19Å; D53-K56 PolarHBondContact O-N 3.23Å; D53-K56 VanDerWaalsContact O-N 3.1Å; D53-K56 WeakPolarHBondContact OD1-CE 3.32Å; D53-K56 IonicContact OD1-NZ 2.65Å; D53-K56 PolarHBondContact OD1-NZ 2.94Å; F54-K56 PolarHBondContact O-N 3.09Å; K56-P60 WeakPolarHBondContact O-CD 3.28Å; K56-P60 VanDerWaalsContact O-CG 3.3Å; K56-P60 WeakPolarHBondContact O-CG 3.45Å; K56-H119 WeakPolarHBondContact CE-CD2 3.25Å; K56-H119 PolarHBondContact NZ-CD2 2.95Å; K56-H119 VanDerWaalsContact NZ-CD2 3.29Å
57	I	94.4	Very high	91.4	Very high	134 Å²	134	64.8 Å²	64.8	69%	0.687	32%	0.322	S	S	*	.	H	α-helix	trans	-105.9	-51.5	178.2	-58.3	175	0	0	0	109.3	F54 K55 A61	F54-I57 PolarHBondContact O-N 3.43Å; F54-I57 VanDerWaalsContact O-N 3.13Å; K55-I57 PolarHBondContact O-N 3.49Å; I57-A61 WeakPolarHBondContact O-CB 3.09Å; I57-A61 PolarHBondContact O-N 3.25Å
58	L	95.1	Very high	92.8	Very high	62 Å²	62	58.6 Å²	58.6	33%	0.325	31%	0.308	S	S	.	.	H	α-helix	trans	-61.4	-50.2	-174.4	179.9	65.5	0	0	0	112.7	F54 V62 P320	F54-L58 HydrophobicContact CD2-CB 4.29Å; F54-L58 HydrophobicContact CD2-CD2 3.87Å; F54-L58 HydrophobicContact CE2-CD2 3.93Å; F54-L58 WeakPolarHBondContact O-CB 3.48Å; F54-L58 PolarHBondContact O-N 2.84Å; L58-V62 HydrophobicContact CD1-CG2 4.1Å; L58-V62 WeakPolarHBondContact O-CG2 3.36Å; L58-V62 PolarHBondContact O-N 3.09Å; L58-V62 VanDerWaalsContact O-N 3.07Å; L58-P320 HydrophobicContact CG-CG 4.46Å
59	L	95.4	Very high	93.6	Very high	2 Å²	2	60.1 Å²	60.1	1%	0.01	31%	0.314	C	S	.	.	H	α-helix	trans	-67.6	-50.1	-175.3	-70.1	160.2	0	0	0	111.6	K55 A61 V62 Y63 Y116 P320	K55-L59 HydrophobicContact CB-CD1 3.67Å; K55-L59 HydrophobicContact CB-CG 4.43Å; K55-L59 HydrophobicContact CG-CD1 4.2Å; K55-L59 WeakPolarHBondContact O-CB 3.4Å; K55-L59 PolarHBondContact O-N 3.01Å; K55-L59 VanDerWaalsContact O-N 3.15Å; L59-A61 PolarHBondContact O-N 3.43Å; L59-V62 PolarHBondContact O-N 3.31Å; L59-Y63 HydrophobicContact CB-CD2 4.47Å; L59-Y63 HydrophobicContact CB-CE2 4.24Å; L59-Y63 HydrophobicContact CD2-CE1 4.26Å; L59-Y63 HydrophobicContact CD2-CE2 4.05Å; L59-Y63 VanDerWaalsContact O-CB 3.25Å; L59-Y63 WeakPolarHBondContact O-CB 3.45Å; L59-Y63 WeakPolarHBondContact O-CD2 3.01Å; L59-Y63 PolarHBondContact O-N 2.88Å; L59-Y116 HydrophobicContact CB-CD2 3.72Å; L59-Y116 HydrophobicContact CB-CE2 4.33Å; L59-Y116 HydrophobicContact CB-CG 3.85Å; L59-Y116 HydrophobicContact CD1-CD1 3.53Å; L59-Y116 HydrophobicContact CD1-CD2 3.84Å; L59-Y116 HydrophobicContact CD1-CE1 3.52Å; L59-Y116 HydrophobicContact CD1-CE2 3.84Å; L59-Y116 HydrophobicContact CD1-CG 3.71Å; L59-Y116 HydrophobicContact CG-CD2 4.33Å; L59-Y116 HydrophobicContact CG-CG 4.42Å; L59-P320 HydrophobicContact CD2-CG 3.77Å
60	P	96.9	Very high	94.2	Very high	10 Å²	10	55.4 Å²	55.4	7%	0.065	29%	0.285	C	S	.	.	H	α-helix	trans	-58.1	-45.7	175.2	-29.1	39.3	0	0	0	112.9	K55 K56 V62 Y63 I64 I113 A117	K55-P60 VanDerWaalsContact O-CD 3.28Å; K55-P60 WeakPolarHBondContact O-CD 3.46Å; K56-P60 WeakPolarHBondContact O-CD 3.28Å; K56-P60 VanDerWaalsContact O-CG 3.3Å; K56-P60 WeakPolarHBondContact O-CG 3.45Å; P60-V62 PolarHBondContact O-N 2.81Å; P60-Y63 PolarHBondContact O-N 3.04Å; P60-I64 WeakPolarHBondContact O-CB 3.28Å; P60-I64 WeakPolarHBondContact O-CD1 3.49Å; P60-I64 WeakPolarHBondContact O-CG1 3.44Å; P60-I64 PolarHBondContact O-N 2.86Å; P60-I113 HydrophobicContact CB-CG2 4.35Å; P60-A117 HydrophobicContact CB-CB 4.49Å; P60-A117 HydrophobicContact CG-CB 4.12Å
61	A	97.3	Very high	94.8	Very high	52 Å²	52	54.1 Å²	54.1	43%	0.43	28%	0.282	S	S	.	.	H	α-helix	trans	-59.1	-49.9	-178.8	0	0	0	0	0	111.8	I57 L59 I64 V65	I57-A61 WeakPolarHBondContact O-CB 3.09Å; I57-A61 PolarHBondContact O-N 3.25Å; L59-A61 PolarHBondContact O-N 3.43Å; A61-I64 PolarHBondContact O-N 3.42Å; A61-V65 WeakPolarHBondContact O-CG2 3.2Å; A61-V65 PolarHBondContact O-N 2.94Å; A61-V65 VanDerWaalsContact O-N 3.17Å
62	V	96.6	Very high	95.2	Very high	30 Å²	30	49.6 Å²	49.6	18%	0.182	27%	0.269	C	S	.	.	H	α-helix	trans	-67.7	-41.5	179.1	179.9	0	0	0	0	111.1	L58 L59 P60 I64 V65 V66 P320 M324	L58-V62 HydrophobicContact CD1-CG2 4.1Å; L58-V62 WeakPolarHBondContact O-CG2 3.36Å; L58-V62 PolarHBondContact O-N 3.09Å; L58-V62 VanDerWaalsContact O-N 3.07Å; L59-V62 PolarHBondContact O-N 3.31Å; P60-V62 PolarHBondContact O-N 2.81Å; V62-I64 VanDerWaalsContact C-N 3.33Å; V62-I64 PolarHBondContact O-N 2.95Å; V62-V65 WeakPolarHBondContact O-CB 3.43Å; V62-V65 PolarHBondContact O-N 3.4Å; V62-V66 HydrophobicContact CG1-CG2 4.13Å; V62-V66 VanDerWaalsContact O-CG2 3.25Å; V62-V66 WeakPolarHBondContact O-CG2 3.3Å; V62-V66 PolarHBondContact O-N 3.27Å; V62-P320 HydrophobicContact CB-CB 3.87Å; V62-P320 HydrophobicContact CG1-CB 3.57Å; V62-P320 HydrophobicContact CG2-CB 4.09Å; V62-M324 HydrophobicContact CG1-CG 4.18Å; V62-M324 HydrophobicContact CG1-SD 4.46Å
63	Y	97.6	Very high	95.6	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-66.6	-32.6	179.1	-68.2	-11.1	0	0	0	113	L59 P60 V66 F67 L109 L112 Y116 S323	L59-Y63 HydrophobicContact CB-CD2 4.47Å; L59-Y63 HydrophobicContact CB-CE2 4.24Å; L59-Y63 HydrophobicContact CD2-CE1 4.26Å; L59-Y63 HydrophobicContact CD2-CE2 4.05Å; L59-Y63 VanDerWaalsContact O-CB 3.25Å; L59-Y63 WeakPolarHBondContact O-CB 3.45Å; L59-Y63 WeakPolarHBondContact O-CD2 3.01Å; L59-Y63 PolarHBondContact O-N 2.88Å; P60-Y63 PolarHBondContact O-N 3.04Å; Y63-V66 PolarHBondContact O-N 3.22Å; Y63-F67 WeakPolarHBondContact O-CB 3.31Å; Y63-F67 PolarHBondContact O-N 2.84Å; Y63-L109 HydrophobicContact CD1-CD2 4.23Å; Y63-L109 HydrophobicContact CD2-CD2 4.36Å; Y63-L109 HydrophobicContact CG-CD2 4.07Å; Y63-L112 HydrophobicContact CD2-CB 3.83Å; Y63-L112 HydrophobicContact CD2-CD1 4.49Å; Y63-L112 HydrophobicContact CE2-CB 3.84Å; Y63-L112 HydrophobicContact CE2-CD1 3.94Å; Y63-L112 HydrophobicContact CE2-CG 4.49Å; Y63-Y116 HydrophobicContact CD2-CD2 4.39Å; Y63-Y116 AromaticContact CE2-CD2 3.98Å; Y63-Y116 HydrophobicContact CE2-CD2 3.98Å; Y63-Y116 AromaticContact CE2-CE2 3.83Å; Y63-Y116 HydrophobicContact CE2-CE2 3.83Å; Y63-S323 VanDerWaalsContact CE1-OG 3.28Å; Y63-S323 WeakPolarHBondContact CE1-OG 3.35Å
64	I	98.1	Very high	95.9	Very high	81 Å²	81	46.4 Å²	46.4	42%	0.415	25%	0.253	S	S	.	.	H	α-helix	trans	-63.1	-46	170.8	-71.5	163.6	0	0	0	110.2	P60 A61 V62 V66 F67 V68 I113	P60-I64 WeakPolarHBondContact O-CB 3.28Å; P60-I64 WeakPolarHBondContact O-CD1 3.49Å; P60-I64 WeakPolarHBondContact O-CG1 3.44Å; P60-I64 PolarHBondContact O-N 2.86Å; A61-I64 PolarHBondContact O-N 3.42Å; V62-I64 VanDerWaalsContact C-N 3.33Å; V62-I64 PolarHBondContact O-N 2.95Å; I64-V66 PolarHBondContact O-N 3.35Å; I64-F67 WeakPolarHBondContact O-CB 3.38Å; I64-F67 PolarHBondContact O-N 2.82Å; I64-V68 HydrophobicContact CG2-CG2 4.27Å; I64-V68 WeakPolarHBondContact O-CB 3.45Å; I64-V68 WeakPolarHBondContact O-CG2 3.14Å; I64-V68 PolarHBondContact O-N 3.31Å; I64-I113 HydrophobicContact CD1-CG2 4.14Å; I64-I113 HydrophobicContact CG1-CD1 3.81Å; I64-I113 HydrophobicContact CG1-CG1 4.19Å; I64-I113 HydrophobicContact CG1-CG2 3.93Å
65	V	97.5	Very high	96	Very high	73 Å²	73	44.6 Å²	44.6	44%	0.442	25%	0.249	S	C	.	.	H	α-helix	trans	-60.8	-47.3	176.6	172.8	0	0	0	0	110.9	A61 V62 F67 V68 L69	A61-V65 WeakPolarHBondContact O-CG2 3.2Å; A61-V65 PolarHBondContact O-N 2.94Å; A61-V65 VanDerWaalsContact O-N 3.17Å; V62-V65 WeakPolarHBondContact O-CB 3.43Å; V62-V65 PolarHBondContact O-N 3.4Å; V65-F67 VanDerWaalsContact C-N 3.27Å; V65-F67 PolarHBondContact O-N 3.49Å; V65-V68 PolarHBondContact O-N 3.09Å; V65-L69 HydrophobicContact CG1-CD1 3.79Å; V65-L69 HydrophobicContact CG1-CG 4.37Å; V65-L69 WeakPolarHBondContact O-CB 3.22Å; V65-L69 WeakPolarHBondContact O-CG 3.41Å; V65-L69 PolarHBondContact O-N 3.28Å
66	V	97.2	Very high	96	Very high	0 Å²	0	48 Å²	48	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-60.5	-39.3	176.6	177.5	0	0	0	0	110.8	V62 Y63 I64 G70 V106 L109 S323 M324 F327	V62-V66 HydrophobicContact CG1-CG2 4.13Å; V62-V66 VanDerWaalsContact O-CG2 3.25Å; V62-V66 WeakPolarHBondContact O-CG2 3.3Å; V62-V66 PolarHBondContact O-N 3.27Å; Y63-V66 PolarHBondContact O-N 3.22Å; I64-V66 PolarHBondContact O-N 3.35Å; V66-G70 WeakPolarHBondContact O-CA 3.33Å; V66-G70 PolarHBondContact O-N 3.38Å; V66-V106 HydrophobicContact CG1-CG2 4.2Å; V66-L109 HydrophobicContact CB-CD1 3.82Å; V66-L109 HydrophobicContact CG1-CD1 3.5Å; V66-S323 VanDerWaalsContact CG1-O 3.28Å; V66-S323 WeakPolarHBondContact CG1-O 3.15Å; V66-M324 HydrophobicContact CG2-CG 4.25Å; V66-F327 HydrophobicContact CB-CD1 4.29Å; V66-F327 HydrophobicContact CG1-CD1 4.39Å; V66-F327 HydrophobicContact CG2-CD1 3.91Å; V66-F327 HydrophobicContact CG2-CE1 3.73Å
67	F	97.9	Very high	95.9	Very high	72 Å²	72	46.7 Å²	46.7	32%	0.316	27%	0.268	S	S	.	.	H	α-helix	trans	-63.9	-55.1	176.7	179.7	-105.1	0	0	0	112.7	Y63 I64 V65 L69 G70 I71 V106 L109 P110 I113	Y63-F67 WeakPolarHBondContact O-CB 3.31Å; Y63-F67 PolarHBondContact O-N 2.84Å; I64-F67 WeakPolarHBondContact O-CB 3.38Å; I64-F67 PolarHBondContact O-N 2.82Å; V65-F67 VanDerWaalsContact C-N 3.27Å; V65-F67 PolarHBondContact O-N 3.49Å; F67-L69 VanDerWaalsContact C-N 3.33Å; F67-L69 PolarHBondContact O-N 3.12Å; F67-G70 PolarHBondContact O-N 2.94Å; F67-I71 HydrophobicContact CD2-CG1 4.03Å; F67-I71 HydrophobicContact CE2-CD1 4.24Å; F67-I71 HydrophobicContact CE2-CG1 3.82Å; F67-I71 HydrophobicContact CZ-CG1 4.34Å; F67-I71 WeakPolarHBondContact O-CG1 3.16Å; F67-I71 PolarHBondContact O-N 3.18Å; F67-V106 HydrophobicContact CB-CG1 4.45Å; F67-V106 HydrophobicContact CD2-CG1 3.95Å; F67-V106 WeakPolarHBondContact CD2-O 3.11Å; F67-L109 HydrophobicContact CB-CD1 4.3Å; F67-P110 HydrophobicContact CD2-CG 4.1Å; F67-P110 HydrophobicContact CE2-CG 3.77Å; F67-P110 HydrophobicContact CZ-CG 4.19Å; F67-I113 HydrophobicContact CB-CD1 4.41Å
68	V	97.8	Very high	95.8	Very high	87 Å²	87	42.1 Å²	42.1	53%	0.527	25%	0.245	S	C	.	.	H	α-helix	trans	-64.3	-36.7	-175.9	171.7	0	0	0	0	111.8	I64 V65 P72	I64-V68 HydrophobicContact CG2-CG2 4.27Å; I64-V68 WeakPolarHBondContact O-CB 3.45Å; I64-V68 WeakPolarHBondContact O-CG2 3.14Å; I64-V68 PolarHBondContact O-N 3.31Å; V65-V68 PolarHBondContact O-N 3.09Å; V68-P72 WeakPolarHBondContact O-CD 3.06Å; V68-P72 WeakPolarHBondContact O-CG 3.36Å
69	L	96.6	Very high	95.6	Very high	71 Å²	71	42.8 Å²	42.8	37%	0.372	25%	0.248	S	C	.	.	H	α-helix	trans	-84.8	-41.4	177.4	-61.6	-178.4	0	0	0	112.4	V65 F67 P72 L73 F327	V65-L69 HydrophobicContact CG1-CD1 3.79Å; V65-L69 HydrophobicContact CG1-CG 4.37Å; V65-L69 WeakPolarHBondContact O-CB 3.22Å; V65-L69 WeakPolarHBondContact O-CG 3.41Å; V65-L69 PolarHBondContact O-N 3.28Å; F67-L69 VanDerWaalsContact C-N 3.33Å; F67-L69 PolarHBondContact O-N 3.12Å; L69-P72 WeakPolarHBondContact O-CD 3.42Å; L69-P72 WeakPolarHBondContact O-CG 3.17Å; L69-L73 HydrophobicContact CB-CD1 4.19Å; L69-L73 VanDerWaalsContact O-CB 3.28Å; L69-L73 WeakPolarHBondContact O-CB 3.28Å; L69-L73 WeakPolarHBondContact O-CD1 3.38Å; L69-L73 WeakPolarHBondContact O-CG 3.32Å; L69-L73 PolarHBondContact O-N 3.07Å; L69-F327 HydrophobicContact CB-CB 3.91Å; L69-F327 HydrophobicContact CB-CG 4.25Å; L69-F327 HydrophobicContact CD1-CD2 4.22Å; L69-F327 HydrophobicContact CD1-CE2 4.49Å; L69-F327 HydrophobicContact CD1-CG 4.34Å
70	G	96.3	Very high	95.2	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-66.9	-41.4	-172.2	0	0	0	0	0	113.5	V66 F67 N74	V66-G70 WeakPolarHBondContact O-CA 3.33Å; V66-G70 PolarHBondContact O-N 3.38Å; F67-G70 PolarHBondContact O-N 2.94Å; G70-N74 WeakPolarHBondContact O-CB 3.39Å; G70-N74 PolarHBondContact O-N 2.88Å; G70-N74 PolarHBondContact O-ND2 3.25Å
71	I	96.6	Very high	94.8	Very high	46 Å²	46	44.1 Å²	44.1	24%	0.236	25%	0.253	C	S	.	.	H	α-helix	trans	-58.2	-59.7	177.9	-67.2	-61.7	0	0	0	111.8	F67 L73 A75 F103 V106 T107	F67-I71 HydrophobicContact CD2-CG1 4.03Å; F67-I71 HydrophobicContact CE2-CD1 4.24Å; F67-I71 HydrophobicContact CE2-CG1 3.82Å; F67-I71 HydrophobicContact CZ-CG1 4.34Å; F67-I71 WeakPolarHBondContact O-CG1 3.16Å; F67-I71 PolarHBondContact O-N 3.18Å; I71-L73 PolarHBondContact O-N 3.15Å; I71-A75 WeakPolarHBondContact O-CB 3.43Å; I71-A75 PolarHBondContact O-N 3.01Å; I71-F103 HydrophobicContact CD1-CD2 4.31Å; I71-F103 HydrophobicContact CD1-CE2 4.02Å; I71-F103 HydrophobicContact CG2-CE2 4.31Å; I71-V106 HydrophobicContact CD1-CB 4.17Å; I71-V106 HydrophobicContact CD1-CG1 3.69Å; I71-V106 HydrophobicContact CG1-CG1 3.7Å; I71-T107 HydrophobicContact CD1-CG2 3.68Å
72	P	95.6	Very high	94.2	Very high	65 Å²	65	49.4 Å²	49.4	42%	0.422	26%	0.262	S	S	.	.	H	α-helix	trans	-65.9	-40.1	-176.6	24.5	-33.8	0	0	0	112.3	V68 L69 V76	V68-P72 WeakPolarHBondContact O-CD 3.06Å; V68-P72 WeakPolarHBondContact O-CG 3.36Å; L69-P72 WeakPolarHBondContact O-CD 3.42Å; L69-P72 WeakPolarHBondContact O-CG 3.17Å; P72-V76 WeakPolarHBondContact O-CB 3.48Å; P72-V76 WeakPolarHBondContact O-CG2 3.47Å; P72-V76 PolarHBondContact O-N 3.07Å
73	L	94.1	Very high	93.7	Very high	52 Å²	52	55.9 Å²	55.9	27%	0.272	28%	0.283	S	S	.	.	H	α-helix	trans	-62.5	-49.5	-178.8	-73.4	170.8	0	0	0	111.8	L69 I71 V76 V77 F327 P330 I331	L69-L73 HydrophobicContact CB-CD1 4.19Å; L69-L73 VanDerWaalsContact O-CB 3.28Å; L69-L73 WeakPolarHBondContact O-CB 3.28Å; L69-L73 WeakPolarHBondContact O-CD1 3.38Å; L69-L73 WeakPolarHBondContact O-CG 3.32Å; L69-L73 PolarHBondContact O-N 3.07Å; I71-L73 PolarHBondContact O-N 3.15Å; L73-V76 PolarHBondContact O-N 3.39Å; L73-V77 WeakPolarHBondContact O-CG2 3.36Å; L73-V77 PolarHBondContact O-N 3.28Å; L73-F327 HydrophobicContact CD1-CB 3.84Å; L73-P330 HydrophobicContact CB-CB 3.95Å; L73-P330 HydrophobicContact CB-CG 4.15Å; L73-I331 HydrophobicContact CD1-CD1 4Å; L73-I331 HydrophobicContact CD1-CG1 3.86Å; L73-I331 HydrophobicContact CD2-CG1 4.4Å
74	N	95.4	Very high	92.9	Very high	1 Å²	1	58.7 Å²	58.7	1%	0.005	30%	0.3	C	S	.	.	H	α-helix	trans	-70.6	-38.7	179.7	-70	-62	0	0	0	112.1	G70 V76 V77 I78 A99 D102 F103 S326 P330	G70-N74 WeakPolarHBondContact O-CB 3.39Å; G70-N74 PolarHBondContact O-N 2.88Å; G70-N74 PolarHBondContact O-ND2 3.25Å; N74-V76 VanDerWaalsContact C-N 3.32Å; N74-V76 PolarHBondContact O-N 3.39Å; N74-V77 PolarHBondContact O-N 3.35Å; N74-I78 VanDerWaalsContact O-CG1 3.3Å; N74-I78 WeakPolarHBondContact O-CG1 3.25Å; N74-I78 PolarHBondContact O-N 3.45Å; N74-A99 HydrophobicContact CB-CB 4.45Å; N74-D102 WeakPolarHBondContact ND2-CB 3.16Å; N74-D102 WeakPolarHBondContact OD1-CB 3.49Å; N74-F103 HydrophobicContact CB-CB 4.13Å; N74-F103 HydrophobicContact CB-CD2 4.33Å; N74-S326 PolarHBondContact ND2-O 2.9Å; N74-P330 WeakPolarHBondContact OD1-CG 3.37Å
75	A	94.6	Very high	91.8	Very high	26 Å²	26	60.6 Å²	60.6	22%	0.215	30%	0.302	C	S	.	.	H	α-helix	trans	-58.6	-43.6	174.5	0	0	0	0	0	111.7	I71 V77 I78 L79 F103	I71-A75 WeakPolarHBondContact O-CB 3.43Å; I71-A75 PolarHBondContact O-N 3.01Å; A75-V77 PolarHBondContact O-N 3.05Å; A75-I78 PolarHBondContact O-N 2.86Å; A75-L79 VanDerWaalsContact O-CB 3.3Å; A75-L79 WeakPolarHBondContact O-CB 3.34Å; A75-L79 WeakPolarHBondContact O-CG 3.3Å; A75-L79 PolarHBondContact O-N 3.04Å; A75-F103 HydrophobicContact CB-CE2 4.28Å
76	V	92.1	Very high	90.6	Very high	89 Å²	89	61.7 Å²	61.7	54%	0.539	31%	0.311	S	S	.	.	H	α-helix	trans	-61.5	-42.3	176.2	167.3	0	0	0	0	111.5	P72 L73 N74 K80	P72-V76 WeakPolarHBondContact O-CB 3.48Å; P72-V76 WeakPolarHBondContact O-CG2 3.47Å; P72-V76 PolarHBondContact O-N 3.07Å; L73-V76 PolarHBondContact O-N 3.39Å; N74-V76 VanDerWaalsContact C-N 3.32Å; N74-V76 PolarHBondContact O-N 3.39Å; V76-K80 WeakPolarHBondContact O-CB 2.97Å; V76-K80 PolarHBondContact O-N 2.93Å
77	V	90.9	Very high	89.3	Confident	27 Å²	27	69.6 Å²	69.6	16%	0.164	35%	0.347	C	S	.	.	H	α-helix	trans	-61.7	-49.8	176.7	173	0	0	0	0	110.7	L73 N74 A75 K80 I81 A99 P330	L73-V77 WeakPolarHBondContact O-CG2 3.36Å; L73-V77 PolarHBondContact O-N 3.28Å; N74-V77 PolarHBondContact O-N 3.35Å; A75-V77 PolarHBondContact O-N 3.05Å; V77-K80 PolarHBondContact O-N 3.43Å; V77-I81 HydrophobicContact CG1-CD1 3.75Å; V77-I81 VanDerWaalsContact O-CG1 3.31Å; V77-I81 WeakPolarHBondContact O-CG1 3.33Å; V77-I81 PolarHBondContact O-N 3.33Å; V77-A99 HydrophobicContact CB-CB 4.07Å; V77-A99 HydrophobicContact CG1-CB 3.7Å; V77-P330 HydrophobicContact CG2-CB 4.24Å
78	I	92.9	Very high	88.5	Confident	39 Å²	39	66.9 Å²	66.9	20%	0.2	34%	0.336	C	S	.	.	H	α-helix	trans	-59	-51.9	179.1	-66.7	165.7	0	0	0	110.3	N74 A75 K80 I81 W82 L96 A99 I100 F103	N74-I78 VanDerWaalsContact O-CG1 3.3Å; N74-I78 WeakPolarHBondContact O-CG1 3.25Å; N74-I78 PolarHBondContact O-N 3.45Å; A75-I78 PolarHBondContact O-N 2.86Å; I78-K80 PolarHBondContact O-N 2.92Å; I78-I81 PolarHBondContact O-N 3.5Å; I78-W82 VanDerWaalsContact O-CB 3.28Å; I78-W82 WeakPolarHBondContact O-CB 3.2Å; I78-W82 PolarHBondContact O-N 2.99Å; I78-L96 HydrophobicContact CB-CD1 4.33Å; I78-L96 HydrophobicContact CG1-CD1 4.15Å; I78-L96 HydrophobicContact CG2-CD1 4.19Å; I78-A99 HydrophobicContact CD1-CB 4.42Å; I78-A99 HydrophobicContact CG1-CB 3.88Å; I78-I100 HydrophobicContact CD1-CG1 4.19Å; I78-I100 HydrophobicContact CG1-CG1 4.35Å; I78-F103 HydrophobicContact CD1-CB 4.04Å; I78-F103 HydrophobicContact CD1-CG 4.26Å
79	L	91	Very high	87.7	Confident	76 Å²	76	65.3 Å²	65.3	40%	0.398	33%	0.329	S	S	.	.	H	α-helix	trans	-62.1	-42	-178.7	-71.6	172.5	0	0	0	112.2	A75 W82 R83	A75-L79 VanDerWaalsContact O-CB 3.3Å; A75-L79 WeakPolarHBondContact O-CB 3.34Å; A75-L79 WeakPolarHBondContact O-CG 3.3Å; A75-L79 PolarHBondContact O-N 3.04Å; L79-W82 HydrophobicContact CD2-CE3 4.35Å; L79-W82 PolarHBondContact O-N 3.31Å; L79-R83 WeakPolarHBondContact O-CB 3.16Å; L79-R83 WeakPolarHBondContact O-CG 3.25Å; L79-R83 PolarHBondContact O-N 3.42Å
80	K	86.8	Confident	87	Confident	40 Å²	40	64.5 Å²	64.5	17%	0.174	32%	0.321	C	S	.	.	H	α-helix	trans	-63.6	-43.9	178.4	-178.1	176.6	-177.5	175.7	0	111.7	V76 V77 I78 T84 Y340 S343 T344	V76-K80 WeakPolarHBondContact O-CB 2.97Å; V76-K80 PolarHBondContact O-N 2.93Å; V77-K80 PolarHBondContact O-N 3.43Å; I78-K80 PolarHBondContact O-N 2.92Å; K80-T84 PolarHBondContact O-N 3.17Å; K80-T84 PolarHBondContact O-OG1 2.88Å; K80-Y340 HydrophobicContact CD-CD1 4.16Å; K80-Y340 HydrophobicContact CD-CE1 3.97Å; K80-Y340 PolarHBondContact NZ-O 3.07Å; K80-S343 VanDerWaalsContact CE-OG 3.28Å; K80-S343 WeakPolarHBondContact CE-OG 3.28Å; K80-S343 PolarHBondContact NZ-OG 2.87Å; K80-T344 PolarHBondContact NZ-OG1 3.28Å; K80-T344 VanDerWaalsContact NZ-OG1 3.07Å
81	I	87.1	Confident	86.3	Confident	0 Å²	0	64.8 Å²	64.8	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-69.8	-40	178.7	-65.5	168.9	0	0	0	110.1	V77 I78 R83 T84 R85 I88 N92 M95 L96	V77-I81 HydrophobicContact CG1-CD1 3.75Å; V77-I81 VanDerWaalsContact O-CG1 3.31Å; V77-I81 WeakPolarHBondContact O-CG1 3.33Å; V77-I81 PolarHBondContact O-N 3.33Å; I78-I81 PolarHBondContact O-N 3.5Å; I81-R83 PolarHBondContact O-N 3.47Å; I81-T84 CarbonylContact O-C 3.45Å; I81-T84 PolarHBondContact O-N 3.29Å; I81-T84 VanDerWaalsContact O-N 3.12Å; I81-T84 PolarHBondContact O-OG1 3.26Å; I81-R85 PolarHBondContact O-N 3.16Å; I81-R85 VanDerWaalsContact O-N 3.09Å; I81-I88 HydrophobicContact CG2-CD1 3.45Å; I81-I88 VanDerWaalsContact CG2-CD1 3.45Å; I81-I88 HydrophobicContact CG2-CG1 4.02Å; I81-N92 HydrophobicContact CD1-CB 4.34Å; I81-N92 HydrophobicContact CG1-CB 4.36Å; I81-N92 HydrophobicContact CG2-CB 4.32Å; I81-M95 HydrophobicContact CD1-CB 4.37Å; I81-L96 HydrophobicContact CB-CD1 4.39Å; I81-L96 HydrophobicContact CD1-CB 3.98Å; I81-L96 HydrophobicContact CG2-CB 4.18Å; I81-L96 HydrophobicContact CG2-CD1 4.36Å; I81-L96 HydrophobicContact CG2-CD2 4.11Å; I81-L96 HydrophobicContact CG2-CG 4.46Å
82	W	86.3	Confident	85.9	Confident	163 Å²	163	63.6 Å²	63.6	62%	0.617	32%	0.316	S	S	*	.	H	α-helix	trans	-61.5	-44.5	177.5	-172.9	50.6	0	0	0	112.2	I78 L79 T84 R85	I78-W82 VanDerWaalsContact O-CB 3.28Å; I78-W82 WeakPolarHBondContact O-CB 3.2Å; I78-W82 PolarHBondContact O-N 2.99Å; L79-W82 HydrophobicContact CD2-CE3 4.35Å; L79-W82 PolarHBondContact O-N 3.31Å; W82-T84 PolarHBondContact O-N 2.96Å; W82-R85 WeakPolarHBondContact O-CB 3.28Å; W82-R85 WeakPolarHBondContact O-CG 3.44Å; W82-R85 PolarHBondContact O-N 2.97Å
83	R	84.9	Confident	85.6	Confident	165 Å²	165	60.5 Å²	60.5	62%	0.623	30%	0.296	S	S	*	.	H	α-helix	trans	-66.2	-18.2	175.1	-72.2	178.6	178.8	167.6	0.7	114.3	L79 I81 F347	L79-R83 WeakPolarHBondContact O-CB 3.16Å; L79-R83 WeakPolarHBondContact O-CG 3.25Å; L79-R83 PolarHBondContact O-N 3.42Å; I81-R83 PolarHBondContact O-N 3.47Å; R83-F347 VanDerWaalsContact NH1-CZ 3.28Å
84	T	80.6	Confident	85.5	Confident	59 Å²	59	58.4 Å²	58.4	36%	0.362	29%	0.285	S	S	.	.	T	Hydrogen-bonded Turn	trans	-110	14.1	179.9	54.6	0	0	0	0	113.1	K80 I81 W82 P86 H87 I88	K80-T84 PolarHBondContact O-N 3.17Å; K80-T84 PolarHBondContact O-OG1 2.88Å; I81-T84 CarbonylContact O-C 3.45Å; I81-T84 PolarHBondContact O-N 3.29Å; I81-T84 VanDerWaalsContact O-N 3.12Å; I81-T84 PolarHBondContact O-OG1 3.26Å; W82-T84 PolarHBondContact O-N 2.96Å; T84-P86 VanDerWaalsContact C-CD 3.42Å; T84-H87 CarbonylContact O-C 3.48Å; T84-H87 PolarHBondContact O-N 3.19Å; T84-I88 PolarHBondContact O-N 3.06Å
85	R	75.1	Confident	85.3	Confident	121 Å²	121	58.8 Å²	58.8	46%	0.457	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-41	-47.3	-179.6	-85.8	-92.2	-174.6	137.2	1.4	116.1	I81 W82 H87 I88	I81-R85 PolarHBondContact O-N 3.16Å; I81-R85 VanDerWaalsContact O-N 3.09Å; W82-R85 WeakPolarHBondContact O-CB 3.28Å; W82-R85 WeakPolarHBondContact O-CG 3.44Å; W82-R85 PolarHBondContact O-N 2.97Å; R85-H87 PolarHBondContact O-N 3.44Å; R85-H87 VanDerWaalsContact O-N 3.15Å; R85-I88 WeakPolarHBondContact O-CB 3.33Å; R85-I88 WeakPolarHBondContact O-CG2 3.2Å; R85-I88 PolarHBondContact O-N 3.18Å
86	P	71.9	Confident	85.2	Confident	96 Å²	96	57.8 Å²	57.8	62%	0.623	28%	0.278	S	S	*	.	G	3₁₀ helix	trans	-61.9	-24.9	-178.7	21.1	-31.9	0	0	0	113.3	T84	T84-P86 VanDerWaalsContact C-CD 3.42Å
87	H	71.9	Confident	85.4	Confident	166 Å²	166	54 Å²	54	77%	0.769	26%	0.255	S	S	*	.	G	3₁₀ helix	trans	-112.7	26.7	179.9	-55	-68.5	0	0	0	112.9	T84 R85 S89	T84-H87 CarbonylContact O-C 3.48Å; T84-H87 PolarHBondContact O-N 3.19Å; R85-H87 PolarHBondContact O-N 3.44Å; R85-H87 VanDerWaalsContact O-N 3.15Å; H87-S89 PolarHBondContact O-N 3.18Å
88	I	79.7	Confident	85.6	Confident	16 Å²	16	53 Å²	53	8%	0.082	25%	0.248	C	C	.	.			trans	-65.5	121.5	-177.3	-163	172.3	0	0	0	111.6	I81 T84 R85 N92 I93	I81-I88 HydrophobicContact CG2-CD1 3.45Å; I81-I88 VanDerWaalsContact CG2-CD1 3.45Å; I81-I88 HydrophobicContact CG2-CG1 4.02Å; T84-I88 PolarHBondContact O-N 3.06Å; R85-I88 WeakPolarHBondContact O-CB 3.33Å; R85-I88 WeakPolarHBondContact O-CG2 3.2Å; R85-I88 PolarHBondContact O-N 3.18Å; I88-N92 HydrophobicContact CD1-CB 4.35Å; I88-N92 HydrophobicContact CG1-CB 3.66Å; I88-I93 HydrophobicContact CD1-CG1 3.73Å; I88-I93 HydrophobicContact CG1-CG1 4.02Å; I88-I93 HydrophobicContact CG2-CG1 4.47Å
89	S	81.9	Confident	85.7	Confident	53 Å²	53	51.3 Å²	51.3	37%	0.371	24%	0.24	S	C	.	.			trans	-79.1	156.5	172.6	75.3	0	0	0	0	111.4	H87 N91 N92 I93	H87-S89 PolarHBondContact O-N 3.18Å; S89-N91 VanDerWaalsContact C-N 3.25Å; S89-N91 PolarHBondContact O-N 2.95Å; S89-N92 WeakPolarHBondContact O-CA 3.42Å; S89-N92 WeakPolarHBondContact O-CB 3.38Å; S89-N92 PolarHBondContact O-N 3.48Å; S89-N92 VanDerWaalsContact OG-CG 3.24Å; S89-N92 PolarHBondContact OG-N 3.46Å; S89-N92 PolarHBondContact OG-ND2 3.36Å; S89-N92 PolarHBondContact OG-OD1 3.38Å; S89-I93 PolarHBondContact O-N 2.83Å; S89-I93 VanDerWaalsContact O-N 3.16Å
90	R	81.8	Confident	85.9	Confident	54 Å²	54	50.5 Å²	50.5	20%	0.204	24%	0.235	C	C	.	.	H	α-helix	trans	-53.7	-41.9	175.2	-67.1	176.4	-73.7	147.2	-0.9	112.8	N92 I93 Y94 N153 L166 G170 A174	R90-N92 VanDerWaalsContact C-N 3.27Å; R90-N92 PolarHBondContact O-N 3.14Å; R90-I93 WeakPolarHBondContact O-CB 3.29Å; R90-I93 PolarHBondContact O-N 3.37Å; R90-Y94 VanDerWaalsContact O-CD2 3.29Å; R90-Y94 WeakPolarHBondContact O-CD2 3.31Å; R90-Y94 PolarHBondContact O-N 3.48Å; R90-N153 PolarHBondContact NH1-OD1 2.91Å; R90-L166 VanDerWaalsContact NH2-CG 3.25Å; R90-G170 WeakPolarHBondContact CD-O 3.44Å; R90-A174 HydrophobicContact CB-CB 4.25Å; R90-A174 HydrophobicContact CG-CB 4.13Å
91	N	82.1	Confident	86.4	Confident	6 Å²	6	48.6 Å²	48.6	3%	0.032	23%	0.227	C	C	.	.	H	α-helix	trans	-61	-36.5	175.5	-166	82	0	0	0	112.2	S89 I93 M95 R154 Q337	S89-N91 VanDerWaalsContact C-N 3.25Å; S89-N91 PolarHBondContact O-N 2.95Å; N91-I93 VanDerWaalsContact C-N 3.31Å; N91-M95 WeakPolarHBondContact ND2-CE 3.32Å; N91-M95 PolarHBondContact ND2-SD 3.37Å; N91-M95 VanDerWaalsContact ND2-SD 3.38Å; N91-M95 VanDerWaalsContact O-CG 3.31Å; N91-M95 WeakPolarHBondContact O-CG 3.41Å; N91-M95 PolarHBondContact O-N 3.34Å; N91-R154 PolarHBondContact ND2-NH2 2.99Å; N91-R154 PolarHBondContact OD1-NH2 3.38Å; N91-Q337 PolarHBondContact ND2-NE2 3.45Å
92	N	86.4	Confident	86.9	Confident	21 Å²	21	48.6 Å²	48.6	11%	0.112	23%	0.227	C	C	.	.	H	α-helix	trans	-70.4	-26.6	175.8	-66.9	-5.1	0	0	0	112.2	I81 I88 S89 R90 M95 L96 Y340	I81-N92 HydrophobicContact CD1-CB 4.34Å; I81-N92 HydrophobicContact CG1-CB 4.36Å; I81-N92 HydrophobicContact CG2-CB 4.32Å; I88-N92 HydrophobicContact CD1-CB 4.35Å; I88-N92 HydrophobicContact CG1-CB 3.66Å; S89-N92 WeakPolarHBondContact O-CA 3.42Å; S89-N92 WeakPolarHBondContact O-CB 3.38Å; S89-N92 PolarHBondContact O-N 3.48Å; S89-N92 VanDerWaalsContact OG-CG 3.24Å; S89-N92 PolarHBondContact OG-N 3.46Å; S89-N92 PolarHBondContact OG-ND2 3.36Å; S89-N92 PolarHBondContact OG-OD1 3.38Å; R90-N92 VanDerWaalsContact C-N 3.27Å; R90-N92 PolarHBondContact O-N 3.14Å; N92-M95 HydrophobicContact CB-CE 4.3Å; N92-M95 WeakPolarHBondContact OD1-CE 3.33Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.31Å; N92-Y340 PolarHBondContact OD1-OH 3.1Å
93	I	91.3	Very high	87.4	Confident	0 Å²	0	44 Å²	44	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-67	-47.3	175	-64.2	172.2	0	0	0	110.2	I88 S89 R90 N91 L96 N97 R171 A174 W175	I88-I93 HydrophobicContact CD1-CG1 3.73Å; I88-I93 HydrophobicContact CG1-CG1 4.02Å; I88-I93 HydrophobicContact CG2-CG1 4.47Å; S89-I93 PolarHBondContact O-N 2.83Å; S89-I93 VanDerWaalsContact O-N 3.16Å; R90-I93 WeakPolarHBondContact O-CB 3.29Å; R90-I93 PolarHBondContact O-N 3.37Å; N91-I93 VanDerWaalsContact C-N 3.31Å; I93-L96 PolarHBondContact O-N 2.86Å; I93-N97 PolarHBondContact O-N 3.35Å; I93-N97 VanDerWaalsContact O-N 3.11Å; I93-N97 PolarHBondContact O-ND2 2.92Å; I93-R171 HydrophobicContact CD1-CG 3.62Å; I93-A174 HydrophobicContact CB-CB 4.41Å; I93-A174 HydrophobicContact CD1-CB 3.93Å; I93-A174 HydrophobicContact CG2-CB 4.39Å; I93-W175 HydrophobicContact CD1-CG 4.33Å; I93-W175 HydrophobicContact CG1-CZ2 4.39Å; I93-W175 HydrophobicContact CG2-CD2 3.8Å; I93-W175 HydrophobicContact CG2-CE3 3.99Å; I93-W175 HydrophobicContact CG2-CG 4.25Å; I93-W175 HydrophobicContact CG2-CH2 4.43Å; I93-W175 HydrophobicContact CG2-CZ2 4.25Å; I93-W175 HydrophobicContact CG2-CZ3 4.3Å
94	Y	91.8	Very high	88	Confident	9 Å²	9	39.8 Å²	39.8	4%	0.035	20%	0.201	C	C	.	.	H	α-helix	trans	-63.5	-44.5	175.8	-57.6	-57.9	0	0	0	111.9	R90 L96 N97 L98 F146 C149 I150 N153 I177 C178	R90-Y94 VanDerWaalsContact O-CD2 3.29Å; R90-Y94 WeakPolarHBondContact O-CD2 3.31Å; R90-Y94 PolarHBondContact O-N 3.48Å; Y94-L96 VanDerWaalsContact C-N 3.29Å; Y94-L96 PolarHBondContact O-N 2.96Å; Y94-N97 PolarHBondContact O-N 3.27Å; Y94-L98 WeakPolarHBondContact O-CB 3.46Å; Y94-L98 PolarHBondContact O-N 2.87Å; Y94-F146 HydrophobicContact CD1-CD1 4.47Å; Y94-C149 HydrophobicContact CD1-CB 3.73Å; Y94-C149 HydrophobicContact CE1-CB 3.74Å; Y94-C149 HydrophobicContact CG-CB 4.15Å; Y94-I150 HydrophobicContact CD2-CG1 4.38Å; Y94-I150 HydrophobicContact CG-CG1 4.26Å; Y94-N153 HydrophobicContact CE2-CB 4.02Å; Y94-I177 HydrophobicContact CE1-CB 4.27Å; Y94-I177 HydrophobicContact CE1-CG2 3.86Å; Y94-I177 WeakPolarHBondContact OH-CD1 3.41Å; Y94-C178 WeakPolarHBondContact CD1-SG 3.23Å
95	M	90.3	Very high	88.8	Confident	9 Å²	9	37 Å²	37	4%	0.044	18%	0.184	C	C	.	.	H	α-helix	trans	-64.1	-32.7	176.7	-70.2	-176.3	-52.3	0	0	112.9	I81 N91 N92 A99 I150 F333 Q337 Y340	I81-M95 HydrophobicContact CD1-CB 4.37Å; N91-M95 WeakPolarHBondContact ND2-CE 3.32Å; N91-M95 PolarHBondContact ND2-SD 3.37Å; N91-M95 VanDerWaalsContact ND2-SD 3.38Å; N91-M95 VanDerWaalsContact O-CG 3.31Å; N91-M95 WeakPolarHBondContact O-CG 3.41Å; N91-M95 PolarHBondContact O-N 3.34Å; N92-M95 HydrophobicContact CB-CE 4.3Å; N92-M95 WeakPolarHBondContact OD1-CE 3.33Å; M95-A99 WeakPolarHBondContact O-CB 3.37Å; M95-A99 PolarHBondContact O-N 2.93Å; M95-I150 HydrophobicContact CG-CD1 4.04Å; M95-F333 HydrophobicContact SD-CD1 4.32Å; M95-F333 HydrophobicContact SD-CG 4.37Å; M95-Q337 PolarHBondContact SD-NE2 3.38Å; M95-Q337 VanDerWaalsContact SD-NE2 3.37Å; M95-Y340 HydrophobicContact CE-CE2 3.78Å; M95-Y340 WeakPolarHBondContact CE-OH 3.31Å
96	L	92.9	Very high	89.9	Confident	5 Å²	5	31.2 Å²	31.2	3%	0.026	16%	0.162	C	C	.	.	H	α-helix	trans	-65.8	-46	174.8	177.1	62.8	0	0	0	111.1	I78 I81 N92 I93 Y94 A99 I100 W175	I78-L96 HydrophobicContact CB-CD1 4.33Å; I78-L96 HydrophobicContact CG1-CD1 4.15Å; I78-L96 HydrophobicContact CG2-CD1 4.19Å; I81-L96 HydrophobicContact CB-CD1 4.39Å; I81-L96 HydrophobicContact CD1-CB 3.98Å; I81-L96 HydrophobicContact CG2-CB 4.18Å; I81-L96 HydrophobicContact CG2-CD1 4.36Å; I81-L96 HydrophobicContact CG2-CD2 4.11Å; I81-L96 HydrophobicContact CG2-CG 4.46Å; N92-L96 WeakPolarHBondContact O-CB 3.49Å; N92-L96 PolarHBondContact O-N 3.31Å; I93-L96 PolarHBondContact O-N 2.86Å; Y94-L96 VanDerWaalsContact C-N 3.29Å; Y94-L96 PolarHBondContact O-N 2.96Å; L96-A99 PolarHBondContact O-N 3.06Å; L96-I100 HydrophobicContact CD1-CD1 4.14Å; L96-I100 HydrophobicContact CD1-CG1 4.43Å; L96-I100 HydrophobicContact CG-CD1 3.97Å; L96-I100 VanDerWaalsContact O-CG1 3.25Å; L96-I100 WeakPolarHBondContact O-CG1 3.38Å; L96-I100 PolarHBondContact O-N 3.11Å; L96-W175 HydrophobicContact CD2-CH2 3.96Å; L96-W175 HydrophobicContact CD2-CZ2 4.47Å
97	N	95.8	Very high	91.1	Very high	10 Å²	10	29.8 Å²	29.8	5%	0.053	15%	0.151	C	C	.	.	H	α-helix	trans	-67.8	-37.8	179.3	-76.2	-89	0	0	0	112.1	I93 Y94 I100 A101 F146 C178 W182	I93-N97 PolarHBondContact O-N 3.35Å; I93-N97 VanDerWaalsContact O-N 3.11Å; I93-N97 PolarHBondContact O-ND2 2.92Å; Y94-N97 PolarHBondContact O-N 3.27Å; N97-I100 PolarHBondContact O-N 3.32Å; N97-A101 PolarHBondContact O-N 3.19Å; N97-F146 HydrophobicContact CB-CD1 4.07Å; N97-F146 HydrophobicContact CB-CD2 4.34Å; N97-F146 HydrophobicContact CB-CE1 3.49Å; N97-F146 VanDerWaalsContact CB-CE1 3.49Å; N97-F146 HydrophobicContact CB-CE2 3.81Å; N97-F146 HydrophobicContact CB-CG 4.5Å; N97-F146 HydrophobicContact CB-CZ 3.38Å; N97-C178 PolarHBondContact ND2-SG 2.94Å; N97-C178 VanDerWaalsContact ND2-SG 3.44Å; N97-W182 PolarHBondContact OD1-NE1 3.44Å
98	L	94.8	Very high	92.3	Very high	5 Å²	5	22.6 Å²	22.6	3%	0.026	12%	0.12	C	C	.	.	H	α-helix	trans	-57.7	-52.4	170.7	-178.9	62.9	0	0	0	111.1	Y94 I100 A101 D102 F146 L147 I150 D329 F333	Y94-L98 WeakPolarHBondContact O-CB 3.46Å; Y94-L98 PolarHBondContact O-N 2.87Å; L98-I100 VanDerWaalsContact C-N 3.27Å; L98-I100 PolarHBondContact O-N 3.05Å; L98-A101 WeakPolarHBondContact O-CB 3.49Å; L98-A101 PolarHBondContact O-N 2.89Å; L98-D102 PolarHBondContact O-N 3.47Å; L98-F146 HydrophobicContact CB-CB 4.18Å; L98-F146 HydrophobicContact CB-CD2 4.47Å; L98-F146 HydrophobicContact CD1-CB 4.29Å; L98-L147 HydrophobicContact CD2-CD2 4.16Å; L98-I150 HydrophobicContact CD2-CD1 4.45Å; L98-D329 HydrophobicContact CD2-CB 4.24Å; L98-F333 HydrophobicContact CD2-CE2 3.81Å
99	A	95.3	Very high	93.1	Very high	3 Å²	3	21.8 Å²	21.8	3%	0.025	12%	0.116	C	C	.	.	H	α-helix	trans	-62.5	-32.6	178.8	0	0	0	0	0	113.1	N74 V77 I78 M95 L96 F103	N74-A99 HydrophobicContact CB-CB 4.45Å; V77-A99 HydrophobicContact CB-CB 4.07Å; V77-A99 HydrophobicContact CG1-CB 3.7Å; I78-A99 HydrophobicContact CD1-CB 4.42Å; I78-A99 HydrophobicContact CG1-CB 3.88Å; M95-A99 WeakPolarHBondContact O-CB 3.37Å; M95-A99 PolarHBondContact O-N 2.93Å; L96-A99 PolarHBondContact O-N 3.06Å; A99-F103 WeakPolarHBondContact O-CB 3.39Å; A99-F103 PolarHBondContact O-N 3.32Å
100	I	96.6	Very high	93.9	Very high	59 Å²	59	22 Å²	22	30%	0.303	12%	0.116	S	C	.	.	H	α-helix	trans	-66.2	-45.9	172.3	-71.1	165	0	0	0	110.3	I78 L96 N97 L98 D102 F103 L104 W182	I78-I100 HydrophobicContact CD1-CG1 4.19Å; I78-I100 HydrophobicContact CG1-CG1 4.35Å; L96-I100 HydrophobicContact CD1-CD1 4.14Å; L96-I100 HydrophobicContact CD1-CG1 4.43Å; L96-I100 HydrophobicContact CG-CD1 3.97Å; L96-I100 VanDerWaalsContact O-CG1 3.25Å; L96-I100 WeakPolarHBondContact O-CG1 3.38Å; L96-I100 PolarHBondContact O-N 3.11Å; N97-I100 PolarHBondContact O-N 3.32Å; L98-I100 VanDerWaalsContact C-N 3.27Å; L98-I100 PolarHBondContact O-N 3.05Å; I100-D102 VanDerWaalsContact C-N 3.34Å; I100-D102 PolarHBondContact O-N 3.13Å; I100-F103 PolarHBondContact O-N 3.06Å; I100-L104 HydrophobicContact CG2-CD1 3.89Å; I100-L104 HydrophobicContact CG2-CG 4.35Å; I100-L104 WeakPolarHBondContact O-CB 3.21Å; I100-L104 VanDerWaalsContact O-CG 3.25Å; I100-L104 WeakPolarHBondContact O-CG 3.37Å; I100-L104 PolarHBondContact O-N 3.04Å; I100-W182 HydrophobicContact CG2-CZ2 4.3Å
101	A	96.9	Very high	94.6	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.7	-42.1	178	0	0	0	0	0	112.1	N97 L98 Y105 N139 W182	N97-A101 PolarHBondContact O-N 3.19Å; L98-A101 WeakPolarHBondContact O-CB 3.49Å; L98-A101 PolarHBondContact O-N 2.89Å; A101-Y105 PolarHBondContact O-N 2.94Å; A101-N139 VanDerWaalsContact C-ND2 3.27Å; A101-N139 PolarHBondContact O-ND2 3.18Å; A101-N139 VanDerWaalsContact O-ND2 3.11Å; A101-W182 HydrophobicContact CB-CH2 3.77Å; A101-W182 HydrophobicContact CB-CZ2 4.17Å
102	D	96.9	Very high	95.3	Very high	1 Å²	1	21.5 Å²	21.5	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-64.3	-49.4	174.7	-68.1	-31.4	0	0	0	111.2	N74 L98 I100 L104 Y105 V106 N139 S326	N74-D102 WeakPolarHBondContact ND2-CB 3.16Å; N74-D102 WeakPolarHBondContact OD1-CB 3.49Å; L98-D102 PolarHBondContact O-N 3.47Å; I100-D102 VanDerWaalsContact C-N 3.34Å; I100-D102 PolarHBondContact O-N 3.13Å; D102-L104 VanDerWaalsContact C-N 3.35Å; D102-L104 PolarHBondContact O-N 3.27Å; D102-Y105 PolarHBondContact O-N 3Å; D102-Y105 VanDerWaalsContact O-N 3.11Å; D102-V106 WeakPolarHBondContact O-CB 3.23Å; D102-V106 WeakPolarHBondContact O-CG2 3.47Å; D102-V106 PolarHBondContact O-N 3.14Å; D102-N139 VanDerWaalsContact CA-ND2 3.26Å; D102-N139 WeakPolarHBondContact CA-ND2 3.27Å; D102-N139 PolarHBondContact N-ND2 3.41Å; D102-N139 PolarHBondContact OD1-ND2 3.48Å; D102-S326 PolarHBondContact OD1-OG 2.62Å
103	F	96.8	Very high	95.9	Very high	66 Å²	66	21.9 Å²	21.9	29%	0.289	12%	0.119	S	C	.	.	H	α-helix	trans	-57.9	-46.6	179.6	-172.7	-92.8	0	0	0	112	I71 N74 A75 I78 A99 I100 Y105 V106 T107	I71-F103 HydrophobicContact CD1-CD2 4.31Å; I71-F103 HydrophobicContact CD1-CE2 4.02Å; I71-F103 HydrophobicContact CG2-CE2 4.31Å; N74-F103 HydrophobicContact CB-CB 4.13Å; N74-F103 HydrophobicContact CB-CD2 4.33Å; A75-F103 HydrophobicContact CB-CE2 4.28Å; I78-F103 HydrophobicContact CD1-CB 4.04Å; I78-F103 HydrophobicContact CD1-CG 4.26Å; A99-F103 WeakPolarHBondContact O-CB 3.39Å; A99-F103 PolarHBondContact O-N 3.32Å; I100-F103 PolarHBondContact O-N 3.06Å; F103-Y105 VanDerWaalsContact C-N 3.28Å; F103-Y105 PolarHBondContact O-N 3.46Å; F103-V106 PolarHBondContact O-N 2.91Å; F103-T107 HydrophobicContact CD1-CG2 4.2Å; F103-T107 HydrophobicContact CE1-CG2 3.86Å; F103-T107 HydrophobicContact CZ-CG2 4.15Å; F103-T107 WeakPolarHBondContact O-CG2 3.37Å; F103-T107 PolarHBondContact O-N 3.5Å; F103-T107 VanDerWaalsContact O-N 3.07Å; F103-T107 PolarHBondContact O-OG1 2.94Å
104	L	96.8	Very high	96.2	Very high	76 Å²	76	26.8 Å²	26.8	40%	0.398	14%	0.138	S	C	.	.	H	α-helix	trans	-62.6	-33	177.7	-70.6	172.3	0	0	0	113	I100 D102 T107 Q135	I100-L104 HydrophobicContact CG2-CD1 3.89Å; I100-L104 HydrophobicContact CG2-CG 4.35Å; I100-L104 WeakPolarHBondContact O-CB 3.21Å; I100-L104 VanDerWaalsContact O-CG 3.25Å; I100-L104 WeakPolarHBondContact O-CG 3.37Å; I100-L104 PolarHBondContact O-N 3.04Å; D102-L104 VanDerWaalsContact C-N 3.35Å; D102-L104 PolarHBondContact O-N 3.27Å; L104-T107 PolarHBondContact O-OG1 2.87Å; L104-Q135 WeakPolarHBondContact O-CG 3.18Å
105	Y	97.7	Very high	96.4	Very high	0 Å²	0	26.4 Å²	26.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-75.8	-44.9	175.7	169.2	-116.9	0	0	0	112.5	A101 D102 F103 T107 S108 L109 Q135 F136 N139 S323 S326	A101-Y105 PolarHBondContact O-N 2.94Å; D102-Y105 PolarHBondContact O-N 3Å; D102-Y105 VanDerWaalsContact O-N 3.11Å; F103-Y105 VanDerWaalsContact C-N 3.28Å; F103-Y105 PolarHBondContact O-N 3.46Å; Y105-T107 VanDerWaalsContact C-N 3.26Å; Y105-T107 PolarHBondContact O-N 3.21Å; Y105-S108 WeakPolarHBondContact O-CA 3.2Å; Y105-S108 WeakPolarHBondContact O-CB 3.05Å; Y105-S108 PolarHBondContact O-N 2.98Å; Y105-S108 PolarHBondContact O-OG 3.07Å; Y105-L109 HydrophobicContact CE1-CD2 4.05Å; Y105-L109 HydrophobicContact CE2-CD2 3.91Å; Y105-L109 PolarHBondContact O-N 3.07Å; Y105-L109 WeakPolarHBondContact OH-CD2 3.43Å; Y105-Q135 HydrophobicContact CD2-CG 4.23Å; Y105-F136 HydrophobicContact CD2-CB 4.36Å; Y105-F136 HydrophobicContact CE2-CB 3.89Å; Y105-F136 AromaticContact CE2-CD2 3.85Å; Y105-F136 HydrophobicContact CE2-CD2 3.85Å; Y105-F136 HydrophobicContact CE2-CG 4.38Å; Y105-F136 AromaticContact CZ-CD2 3.8Å; Y105-F136 WeakPolarHBondContact OH-CD2 3.41Å; Y105-N139 HydrophobicContact CD1-CB 4.34Å; Y105-N139 HydrophobicContact CG-CB 3.91Å; Y105-S323 WeakPolarHBondContact OH-CB 3.31Å; Y105-S323 PolarHBondContact OH-OG 3.47Å; Y105-S326 WeakPolarHBondContact CD1-OG 3.37Å
106	V	97.8	Very high	96.6	Very high	0 Å²	0	26.1 Å²	26.1	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-61.2	-37.4	-179	178.7	0	0	0	0	111	V66 F67 I71 D102 F103 S108 L109	V66-V106 HydrophobicContact CG1-CG2 4.2Å; F67-V106 HydrophobicContact CB-CG1 4.45Å; F67-V106 HydrophobicContact CD2-CG1 3.95Å; F67-V106 WeakPolarHBondContact CD2-O 3.11Å; I71-V106 HydrophobicContact CD1-CB 4.17Å; I71-V106 HydrophobicContact CD1-CG1 3.69Å; I71-V106 HydrophobicContact CG1-CG1 3.7Å; D102-V106 WeakPolarHBondContact O-CB 3.23Å; D102-V106 WeakPolarHBondContact O-CG2 3.47Å; D102-V106 PolarHBondContact O-N 3.14Å; F103-V106 PolarHBondContact O-N 2.91Å; V106-S108 PolarHBondContact O-N 3.39Å; V106-L109 HydrophobicContact CB-CD1 4.46Å; V106-L109 HydrophobicContact CG1-CD1 4.2Å; V106-L109 HydrophobicContact CG2-CD1 4.49Å; V106-L109 WeakPolarHBondContact O-CB 3.32Å; V106-L109 PolarHBondContact O-N 3.23Å; V106-L109 VanDerWaalsContact O-N 3.15Å
107	T	97.3	Very high	96.8	Very high	66 Å²	66	28.2 Å²	28.2	41%	0.405	15%	0.153	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-20	174.8	55.1	0	0	0	0	113.9	I71 F103 L104 Y105 P110	I71-T107 HydrophobicContact CD1-CG2 3.68Å; F103-T107 HydrophobicContact CD1-CG2 4.2Å; F103-T107 HydrophobicContact CE1-CG2 3.86Å; F103-T107 HydrophobicContact CZ-CG2 4.15Å; F103-T107 WeakPolarHBondContact O-CG2 3.37Å; F103-T107 PolarHBondContact O-N 3.5Å; F103-T107 VanDerWaalsContact O-N 3.07Å; F103-T107 PolarHBondContact O-OG1 2.94Å; L104-T107 PolarHBondContact O-OG1 2.87Å; Y105-T107 VanDerWaalsContact C-N 3.26Å; Y105-T107 PolarHBondContact O-N 3.21Å; T107-P110 WeakPolarHBondContact O-CD 3.46Å
108	S	96.8	Very high	96.8	Very high	15 Å²	15	29.3 Å²	29.3	11%	0.105	16%	0.161	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.6	-16.3	176.1	80.5	0	0	0	0	113.8	Y105 V106 L111	Y105-S108 WeakPolarHBondContact O-CA 3.2Å; Y105-S108 WeakPolarHBondContact O-CB 3.05Å; Y105-S108 PolarHBondContact O-N 2.98Å; Y105-S108 PolarHBondContact O-OG 3.07Å; V106-S108 PolarHBondContact O-N 3.39Å; S108-L111 PolarHBondContact O-N 3.43Å
109	L	97.4	Very high	96.7	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-59	-34.9	-177.1	-69.7	179.1	0	0	0	115.6	Y63 V66 F67 Y105 V106 L111 L112 I113	Y63-L109 HydrophobicContact CD1-CD2 4.23Å; Y63-L109 HydrophobicContact CD2-CD2 4.36Å; Y63-L109 HydrophobicContact CG-CD2 4.07Å; V66-L109 HydrophobicContact CB-CD1 3.82Å; V66-L109 HydrophobicContact CG1-CD1 3.5Å; F67-L109 HydrophobicContact CB-CD1 4.3Å; Y105-L109 HydrophobicContact CE1-CD2 4.05Å; Y105-L109 HydrophobicContact CE2-CD2 3.91Å; Y105-L109 PolarHBondContact O-N 3.07Å; Y105-L109 WeakPolarHBondContact OH-CD2 3.43Å; V106-L109 HydrophobicContact CB-CD1 4.46Å; V106-L109 HydrophobicContact CG1-CD1 4.2Å; V106-L109 HydrophobicContact CG2-CD1 4.49Å; V106-L109 WeakPolarHBondContact O-CB 3.32Å; V106-L109 PolarHBondContact O-N 3.23Å; V106-L109 VanDerWaalsContact O-N 3.15Å; L109-L111 PolarHBondContact O-N 3.38Å; L109-L111 VanDerWaalsContact O-N 3.13Å; L109-L112 HydrophobicContact CD2-CD1 4.24Å; L109-L112 WeakPolarHBondContact O-CA 3.49Å; L109-L112 PolarHBondContact O-N 2.99Å; L109-I113 HydrophobicContact CB-CD1 4.31Å; L109-I113 WeakPolarHBondContact O-CG1 3.37Å; L109-I113 PolarHBondContact O-N 3.47Å
110	P	97.9	Very high	96.7	Very high	57 Å²	57	35 Å²	35	37%	0.37	19%	0.188	S	C	.	.	H	α-helix	trans	-52.9	-35.9	177.9	-29.9	37.7	0	0	0	113.8	F67 T107 I113 Y114	F67-P110 HydrophobicContact CD2-CG 4.1Å; F67-P110 HydrophobicContact CE2-CG 3.77Å; F67-P110 HydrophobicContact CZ-CG 4.19Å; T107-P110 WeakPolarHBondContact O-CD 3.46Å; P110-I113 PolarHBondContact O-N 3.46Å; P110-Y114 PolarHBondContact O-N 2.76Å
111	L	97.9	Very high	96.6	Very high	50 Å²	50	36.5 Å²	36.5	26%	0.262	19%	0.191	S	C	.	.	H	α-helix	trans	-66.5	-40.2	176.7	-62.3	170.9	0	0	0	111.9	S108 L109 N115 W122 F124 V132	S108-L111 PolarHBondContact O-N 3.43Å; L109-L111 PolarHBondContact O-N 3.38Å; L109-L111 VanDerWaalsContact O-N 3.13Å; L111-N115 WeakPolarHBondContact O-CB 3.36Å; L111-N115 PolarHBondContact O-N 3.22Å; L111-W122 HydrophobicContact CB-CH2 3.79Å; L111-W122 HydrophobicContact CB-CZ3 4.2Å; L111-F124 HydrophobicContact CB-CD2 4.37Å; L111-F124 HydrophobicContact CB-CE2 4.28Å; L111-F124 HydrophobicContact CD2-CB 4.35Å; L111-F124 HydrophobicContact CD2-CD1 3.59Å; L111-F124 HydrophobicContact CD2-CD2 3.67Å; L111-F124 HydrophobicContact CD2-CE1 3.65Å; L111-F124 HydrophobicContact CD2-CE2 3.72Å; L111-F124 HydrophobicContact CD2-CG 3.6Å; L111-F124 HydrophobicContact CD2-CZ 3.72Å; L111-V132 HydrophobicContact CB-CG2 4.16Å; L111-V132 HydrophobicContact CD1-CG2 3.51Å; L111-V132 HydrophobicContact CG-CG2 4.47Å
112	L	96.6	Very high	96.7	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-71.7	-38.3	175.9	-67.7	179.1	0	0	0	112.2	Y63 L109 Y114 N115 Y116 W122 V132	Y63-L112 HydrophobicContact CD2-CB 3.83Å; Y63-L112 HydrophobicContact CD2-CD1 4.49Å; Y63-L112 HydrophobicContact CE2-CB 3.84Å; Y63-L112 HydrophobicContact CE2-CD1 3.94Å; Y63-L112 HydrophobicContact CE2-CG 4.49Å; L109-L112 HydrophobicContact CD2-CD1 4.24Å; L109-L112 WeakPolarHBondContact O-CA 3.49Å; L109-L112 PolarHBondContact O-N 2.99Å; L112-Y114 VanDerWaalsContact C-N 3.35Å; L112-N115 WeakPolarHBondContact O-CB 3.34Å; L112-N115 PolarHBondContact O-N 3.12Å; L112-Y116 HydrophobicContact CB-CD2 4.42Å; L112-Y116 HydrophobicContact CB-CE2 4.31Å; L112-Y116 HydrophobicContact CD2-CE2 4.24Å; L112-Y116 WeakPolarHBondContact O-CD2 3.49Å; L112-Y116 PolarHBondContact O-N 3.38Å; L112-W122 HydrophobicContact CD2-CZ3 4.43Å; L112-V132 HydrophobicContact CD1-CG1 3.71Å; L112-V132 HydrophobicContact CD2-CG1 3.46Å; L112-V132 VanDerWaalsContact CD2-CG1 3.46Å; L112-V132 HydrophobicContact CG-CG1 3.42Å; L112-V132 VanDerWaalsContact CG-CG1 3.42Å
113	I	97.8	Very high	96.6	Very high	28 Å²	28	39.3 Å²	39.3	14%	0.144	21%	0.209	C	C	.	.	H	α-helix	trans	-58.1	-51.1	175.4	-68.2	162.6	0	0	0	109.1	P60 I64 F67 L109 P110 N115 Y116 A117	P60-I113 HydrophobicContact CB-CG2 4.35Å; I64-I113 HydrophobicContact CD1-CG2 4.14Å; I64-I113 HydrophobicContact CG1-CD1 3.81Å; I64-I113 HydrophobicContact CG1-CG1 4.19Å; I64-I113 HydrophobicContact CG1-CG2 3.93Å; F67-I113 HydrophobicContact CB-CD1 4.41Å; L109-I113 HydrophobicContact CB-CD1 4.31Å; L109-I113 WeakPolarHBondContact O-CG1 3.37Å; L109-I113 PolarHBondContact O-N 3.47Å; P110-I113 PolarHBondContact O-N 3.46Å; I113-N115 VanDerWaalsContact C-N 3.33Å; I113-N115 PolarHBondContact O-N 3.18Å; I113-Y116 PolarHBondContact O-N 2.62Å; I113-A117 WeakPolarHBondContact O-CB 3.26Å; I113-A117 PolarHBondContact O-N 3.47Å
114	Y	97.8	Very high	96.7	Very high	103 Å²	103	40 Å²	40	40%	0.404	21%	0.212	S	C	.	.	H	α-helix	trans	-59.1	-44.9	175.9	-178.3	-86.4	0	0	0	111.7	P110 L112 Y116 S118 Y121 P123 F124	P110-Y114 PolarHBondContact O-N 2.76Å; L112-Y114 VanDerWaalsContact C-N 3.35Å; Y114-Y116 PolarHBondContact O-N 2.82Å; Y114-S118 WeakPolarHBondContact CE1-OG 3.21Å; Y114-S118 WeakPolarHBondContact O-CB 3.34Å; Y114-S118 PolarHBondContact O-N 3.06Å; Y114-S118 PolarHBondContact O-OG 3.11Å; Y114-Y121 HydrophobicContact CE1-CD1 4.22Å; Y114-P123 HydrophobicContact CD1-CG 4.26Å; Y114-P123 HydrophobicContact CE1-CG 3.6Å; Y114-F124 AromaticContact CD1-CE2 3.64Å; Y114-F124 HydrophobicContact CD1-CE2 3.64Å; Y114-F124 AromaticContact CD1-CZ 3.53Å; Y114-F124 HydrophobicContact CD1-CZ 3.53Å; Y114-F124 HydrophobicContact CE1-CE2 4.41Å; Y114-F124 HydrophobicContact CE1-CZ 4.17Å; Y114-F124 HydrophobicContact CG-CE2 4.18Å; Y114-F124 AromaticContact CG-CZ 3.78Å; Y114-F124 HydrophobicContact CG-CZ 3.78Å
115	N	96.2	Very high	96.7	Very high	2 Å²	2	38.2 Å²	38.2	1%	0.011	21%	0.212	C	C	.	.	H	α-helix	trans	-57.5	-51.5	-178.7	179	-120.9	0	0	0	112.4	L111 L112 I113 S118 D120 Y121 W122	L111-N115 WeakPolarHBondContact O-CB 3.36Å; L111-N115 PolarHBondContact O-N 3.22Å; L112-N115 WeakPolarHBondContact O-CB 3.34Å; L112-N115 PolarHBondContact O-N 3.12Å; I113-N115 VanDerWaalsContact C-N 3.33Å; I113-N115 PolarHBondContact O-N 3.18Å; N115-S118 CarbonylContact O-C 3.51Å; N115-S118 PolarHBondContact O-N 2.83Å; N115-D120 PolarHBondContact ND2-O 3.32Å; N115-D120 CarbonylContact O-C 3.57Å; N115-D120 WeakPolarHBondContact O-CA 3.5Å; N115-D120 PolarHBondContact O-N 2.74Å; N115-Y121 WeakPolarHBondContact CA-O 3.47Å; N115-Y121 VanDerWaalsContact ND2-C 3.29Å; N115-Y121 PolarHBondContact ND2-O 2.93Å; N115-W122 HydrophobicContact CB-CE3 3.75Å; N115-W122 HydrophobicContact CB-CZ3 3.97Å
116	Y	95.8	Very high	96.6	Very high	2 Å²	2	42.4 Å²	42.4	1%	0.008	23%	0.231	C	C	.	.	H	α-helix	trans	-75.4	-35.4	-177.4	-67.7	-61.5	0	0	0	112.8	K55 L59 Y63 L112 I113 Y114 S118 H119 D120 D209 R319	K55-Y116 HydrophobicContact CD-CD1 4.39Å; K55-Y116 HydrophobicContact CD-CE1 4.46Å; K55-Y116 HydrophobicContact CG-CD1 4.27Å; L59-Y116 HydrophobicContact CB-CD2 3.72Å; L59-Y116 HydrophobicContact CB-CE2 4.33Å; L59-Y116 HydrophobicContact CB-CG 3.85Å; L59-Y116 HydrophobicContact CD1-CD1 3.53Å; L59-Y116 HydrophobicContact CD1-CD2 3.84Å; L59-Y116 HydrophobicContact CD1-CE1 3.52Å; L59-Y116 HydrophobicContact CD1-CE2 3.84Å; L59-Y116 HydrophobicContact CD1-CG 3.71Å; L59-Y116 HydrophobicContact CG-CD2 4.33Å; L59-Y116 HydrophobicContact CG-CG 4.42Å; Y63-Y116 HydrophobicContact CD2-CD2 4.39Å; Y63-Y116 AromaticContact CE2-CD2 3.98Å; Y63-Y116 HydrophobicContact CE2-CD2 3.98Å; Y63-Y116 AromaticContact CE2-CE2 3.83Å; Y63-Y116 HydrophobicContact CE2-CE2 3.83Å; L112-Y116 HydrophobicContact CB-CD2 4.42Å; L112-Y116 HydrophobicContact CB-CE2 4.31Å; L112-Y116 HydrophobicContact CD2-CE2 4.24Å; L112-Y116 WeakPolarHBondContact O-CD2 3.49Å; L112-Y116 PolarHBondContact O-N 3.38Å; I113-Y116 PolarHBondContact O-N 2.62Å; Y114-Y116 PolarHBondContact O-N 2.82Å; Y116-S118 VanDerWaalsContact C-N 3.3Å; Y116-S118 PolarHBondContact O-N 2.98Å; Y116-H119 PolarHBondContact O-N 3.29Å; Y116-D120 WeakPolarHBondContact CD1-OD1 3.44Å; Y116-D209 PolarHBondContact OH-OD1 3.26Å; Y116-R319 PolarHBondContact OH-NH1 2.87Å
117	A	96.4	Very high	96.6	Very high	50 Å²	50	47.9 Å²	47.9	41%	0.413	26%	0.26	S	S	.	.	H	α-helix	trans	-64.6	-36.6	173.6	0	0	0	0	0	111.6	P60 I113 H119	P60-A117 HydrophobicContact CB-CB 4.49Å; P60-A117 HydrophobicContact CG-CB 4.12Å; I113-A117 WeakPolarHBondContact O-CB 3.26Å; I113-A117 PolarHBondContact O-N 3.47Å; A117-H119 PolarHBondContact O-N 3.36Å; A117-H119 PolarHBondContact O-ND1 2.65Å
118	S	95.9	Very high	96.6	Very high	32 Å²	32	45.7 Å²	45.7	22%	0.224	25%	0.248	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.7	28.3	177.8	-53.4	0	0	0	0	113.2	Y114 N115 Y116 D120 Y121	Y114-S118 WeakPolarHBondContact CE1-OG 3.21Å; Y114-S118 WeakPolarHBondContact O-CB 3.34Å; Y114-S118 PolarHBondContact O-N 3.06Å; Y114-S118 PolarHBondContact O-OG 3.11Å; N115-S118 CarbonylContact O-C 3.51Å; N115-S118 PolarHBondContact O-N 2.83Å; Y116-S118 VanDerWaalsContact C-N 3.3Å; Y116-S118 PolarHBondContact O-N 2.98Å; S118-D120 PolarHBondContact O-N 3.49Å; S118-Y121 WeakPolarHBondContact O-CB 3.45Å; S118-Y121 PolarHBondContact O-N 3.35Å
119	H	92.9	Very high	96.7	Very high	97 Å²	97	45 Å²	45	45%	0.449	24%	0.243	S	C	.	.	T	Hydrogen-bonded Turn	trans	59	50.1	174.4	-58.5	56	0	0	0	113.2	K56 Y116 A117 Y121	K56-H119 WeakPolarHBondContact CE-CD2 3.25Å; K56-H119 PolarHBondContact NZ-CD2 2.95Å; K56-H119 VanDerWaalsContact NZ-CD2 3.29Å; Y116-H119 PolarHBondContact O-N 3.29Å; A117-H119 PolarHBondContact O-N 3.36Å; A117-H119 PolarHBondContact O-ND1 2.65Å; H119-Y121 PolarHBondContact O-N 3.39Å
120	D	93.8	Very high	96.7	Very high	31 Å²	31	47 Å²	47	17%	0.166	25%	0.252	C	S	.	.	T	Hydrogen-bonded Turn	trans	64.4	8.6	-176.5	-52.5	-55.6	0	0	0	115.4	K55 N115 Y116 S118 W122 V206	K55-D120 VanDerWaalsContact CE-CG 3.46Å; K55-D120 WeakPolarHBondContact CE-OD1 3.44Å; K55-D120 WeakPolarHBondContact CE-OD2 3.44Å; K55-D120 VanDerWaalsContact NZ-CG 3.27Å; K55-D120 IonicContact NZ-OD1 2.65Å; K55-D120 PolarHBondContact NZ-OD1 3.46Å; K55-D120 IonicContact NZ-OD2 2.78Å; K55-D120 PolarHBondContact NZ-OD2 2.78Å; N115-D120 PolarHBondContact ND2-O 3.32Å; N115-D120 CarbonylContact O-C 3.57Å; N115-D120 WeakPolarHBondContact O-CA 3.5Å; N115-D120 PolarHBondContact O-N 2.74Å; Y116-D120 WeakPolarHBondContact CD1-OD1 3.44Å; S118-D120 PolarHBondContact O-N 3.49Å; D120-W122 PolarHBondContact O-N 3.36Å; D120-V206 HydrophobicContact CB-CG1 4.2Å
121	Y	95.9	Very high	96.7	Very high	91 Å²	91	48.3 Å²	48.3	36%	0.357	26%	0.256	S	S	.	.	B	Isolated β-bridge	trans	-66.9	131.3	177.2	179.2	-122.3	0	0	0	111.8	Y114 N115 S118 H119 P123 R204 T205	Y114-Y121 HydrophobicContact CE1-CD1 4.22Å; N115-Y121 WeakPolarHBondContact CA-O 3.47Å; N115-Y121 VanDerWaalsContact ND2-C 3.29Å; N115-Y121 PolarHBondContact ND2-O 2.93Å; S118-Y121 WeakPolarHBondContact O-CB 3.45Å; S118-Y121 PolarHBondContact O-N 3.35Å; H119-Y121 PolarHBondContact O-N 3.39Å; Y121-P123 HydrophobicContact CD1-CG 4.36Å; Y121-P123 HydrophobicContact CE1-CB 3.75Å; Y121-P123 HydrophobicContact CE1-CG 3.97Å; Y121-R204 HydrophobicContact CD2-CB 4.41Å; Y121-T205 CarbonylContact C-O 3.58Å; Y121-T205 WeakPolarHBondContact CA-O 3.26Å
122	W	97.4	Very high	96.7	Very high	2 Å²	2	46.1 Å²	46.1	1%	0.008	24%	0.244	C	C	.	.			trans	-124	95.8	-177.6	-172.2	-90.7	0	0	0	111.8	L111 L112 N115 D120 F124 G125 A128 C129 V132 T205 C207	L111-W122 HydrophobicContact CB-CH2 3.79Å; L111-W122 HydrophobicContact CB-CZ3 4.2Å; L112-W122 HydrophobicContact CD2-CZ3 4.43Å; N115-W122 HydrophobicContact CB-CE3 3.75Å; N115-W122 HydrophobicContact CB-CZ3 3.97Å; D120-W122 PolarHBondContact O-N 3.36Å; W122-F124 AromaticContact CD2-CD2 3.93Å; W122-F124 HydrophobicContact CD2-CD2 3.93Å; W122-F124 AromaticContact CE2-CD2 3.85Å; W122-F124 AromaticContact CE3-CD2 3.99Å; W122-F124 HydrophobicContact CE3-CD2 3.99Å; W122-F124 AromaticContact CH2-CD2 3.91Å; W122-F124 HydrophobicContact CH2-CD2 3.91Å; W122-F124 HydrophobicContact CZ2-CB 3.85Å; W122-F124 AromaticContact CZ2-CD2 3.82Å; W122-F124 HydrophobicContact CZ2-CD2 3.82Å; W122-F124 HydrophobicContact CZ2-CG 4.3Å; W122-F124 AromaticContact CZ3-CD2 3.98Å; W122-F124 HydrophobicContact CZ3-CD2 3.98Å; W122-F124 HydrophobicContact CZ3-CE2 4.44Å; W122-G125 PolarHBondContact NE1-O 3.43Å; W122-A128 VanDerWaalsContact CZ2-C 3.49Å; W122-A128 HydrophobicContact CZ2-CB 3.8Å; W122-C129 VanDerWaalsContact CZ2-CA 3.49Å; W122-C129 HydrophobicContact CZ2-CB 4.08Å; W122-C129 VanDerWaalsContact CZ2-N 3.3Å; W122-V132 HydrophobicContact CH2-CB 4.35Å; W122-V132 HydrophobicContact CH2-CG2 4.08Å; W122-T205 PolarHBondContact N-O 3.4Å; W122-T205 WeakPolarHBondContact O-CG2 3.47Å; W122-C207 HydrophobicContact CB-CB 3.95Å; W122-C207 HydrophobicContact CD2-CB 3.53Å; W122-C207 HydrophobicContact CE3-CB 3.77Å; W122-C207 HydrophobicContact CG-CB 3.59Å
123	P	96.8	Very high	96.7	Very high	58 Å²	58	46.2 Å²	46.2	38%	0.377	25%	0.245	S	C	.	.			trans	-87.4	-10	178.9	33.1	-35	0	0	0	114.2	Y114 Y121 G125	Y114-P123 HydrophobicContact CD1-CG 4.26Å; Y114-P123 HydrophobicContact CE1-CG 3.6Å; Y121-P123 HydrophobicContact CD1-CG 4.36Å; Y121-P123 HydrophobicContact CE1-CB 3.75Å; Y121-P123 HydrophobicContact CE1-CG 3.97Å; P123-G125 PolarHBondContact O-N 3.21Å
124	F	97.4	Very high	96.7	Very high	80 Å²	80	46.1 Å²	46.1	35%	0.351	24%	0.243	S	C	.	.	S	Bend	trans	-82.1	6.9	-166.5	-48.4	-70.4	0	0	0	115.1	L111 Y114 W122 A128	L111-F124 HydrophobicContact CB-CD2 4.37Å; L111-F124 HydrophobicContact CB-CE2 4.28Å; L111-F124 HydrophobicContact CD2-CB 4.35Å; L111-F124 HydrophobicContact CD2-CD1 3.59Å; L111-F124 HydrophobicContact CD2-CD2 3.67Å; L111-F124 HydrophobicContact CD2-CE1 3.65Å; L111-F124 HydrophobicContact CD2-CE2 3.72Å; L111-F124 HydrophobicContact CD2-CG 3.6Å; L111-F124 HydrophobicContact CD2-CZ 3.72Å; Y114-F124 AromaticContact CD1-CE2 3.64Å; Y114-F124 HydrophobicContact CD1-CE2 3.64Å; Y114-F124 AromaticContact CD1-CZ 3.53Å; Y114-F124 HydrophobicContact CD1-CZ 3.53Å; Y114-F124 HydrophobicContact CE1-CE2 4.41Å; Y114-F124 HydrophobicContact CE1-CZ 4.17Å; Y114-F124 HydrophobicContact CG-CE2 4.18Å; Y114-F124 AromaticContact CG-CZ 3.78Å; Y114-F124 HydrophobicContact CG-CZ 3.78Å; W122-F124 AromaticContact CD2-CD2 3.93Å; W122-F124 HydrophobicContact CD2-CD2 3.93Å; W122-F124 AromaticContact CE2-CD2 3.85Å; W122-F124 AromaticContact CE3-CD2 3.99Å; W122-F124 HydrophobicContact CE3-CD2 3.99Å; W122-F124 AromaticContact CH2-CD2 3.91Å; W122-F124 HydrophobicContact CH2-CD2 3.91Å; W122-F124 HydrophobicContact CZ2-CB 3.85Å; W122-F124 AromaticContact CZ2-CD2 3.82Å; W122-F124 HydrophobicContact CZ2-CD2 3.82Å; W122-F124 HydrophobicContact CZ2-CG 4.3Å; W122-F124 AromaticContact CZ3-CD2 3.98Å; W122-F124 HydrophobicContact CZ3-CD2 3.98Å; W122-F124 HydrophobicContact CZ3-CE2 4.44Å; F124-A128 HydrophobicContact CB-CB 3.76Å; F124-A128 VanDerWaalsContact O-CB 3.25Å; F124-A128 WeakPolarHBondContact O-CB 3.36Å
125	G	97	Very high	96.6	Very high	38 Å²	38	42.9 Å²	42.9	39%	0.392	23%	0.232	S	C	.	.	H	α-helix	trans	77.2	169.6	-178.7	0	0	0	0	0	114.8	W122 P123 C129	W122-G125 PolarHBondContact NE1-O 3.43Å; P123-G125 PolarHBondContact O-N 3.21Å; G125-C129 PolarHBondContact O-N 3.44Å
126	E	96.6	Very high	96.6	Very high	88 Å²	88	43 Å²	43	41%	0.411	23%	0.232	S	C	.	.	H	α-helix	trans	-68.5	-38.4	-172.2	-170.2	177.1	159.3	0	0	113.2	A128 C129 K130 T198	E126-A128 PolarHBondContact O-N 3.07Å; E126-C129 WeakPolarHBondContact O-CB 3.47Å; E126-C129 PolarHBondContact O-N 2.64Å; E126-K130 HydrophobicContact CG-CD 4.36Å; E126-K130 PolarHBondContact O-N 2.93Å; E126-K130 WeakPolarHBondContact OE1-CE 3.12Å; E126-K130 IonicContact OE1-NZ 3.87Å; E126-K130 PolarHBondContact OE1-NZ 3.37Å; E126-T198 HydrophobicContact CB-CG2 4.37Å
127	L	97.3	Very high	96.7	Very high	116 Å²	116	43 Å²	43	61%	0.607	23%	0.232	S	C	*	.	H	α-helix	trans	-60.7	-46.5	179.4	178.4	61.5	0	0	0	111.5	C129 K130 L131	L127-C129 VanDerWaalsContact C-N 3.29Å; L127-C129 PolarHBondContact O-N 3.37Å; L127-K130 PolarHBondContact O-N 3.3Å; L127-L131 HydrophobicContact CD1-CD1 4.17Å; L127-L131 HydrophobicContact CD1-CG 4.18Å; L127-L131 HydrophobicContact CG-CD1 3.93Å; L127-L131 HydrophobicContact CG-CG 4.39Å; L127-L131 WeakPolarHBondContact O-CB 3.47Å; L127-L131 WeakPolarHBondContact O-CG 3.03Å; L127-L131 PolarHBondContact O-N 3.37Å
128	A	97.8	Very high	96.7	Very high	19 Å²	19	40.8 Å²	40.8	16%	0.157	21%	0.214	C	C	.	.	H	α-helix	trans	-62.6	-38.3	177	0	0	0	0	0	111.5	W122 F124 E126 L131 V132	W122-A128 VanDerWaalsContact CZ2-C 3.49Å; W122-A128 HydrophobicContact CZ2-CB 3.8Å; F124-A128 HydrophobicContact CB-CB 3.76Å; F124-A128 VanDerWaalsContact O-CB 3.25Å; F124-A128 WeakPolarHBondContact O-CB 3.36Å; E126-A128 PolarHBondContact O-N 3.07Å; A128-L131 PolarHBondContact O-N 3.15Å; A128-V132 WeakPolarHBondContact O-CB 3.47Å; A128-V132 VanDerWaalsContact O-CG2 3.27Å; A128-V132 WeakPolarHBondContact O-CG2 3.43Å; A128-V132 PolarHBondContact O-N 3.37Å
129	C	97.9	Very high	96.8	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-58.2	-52.1	175	174.5	0	0	0	0	110	W122 G125 E126 L127 L131 V132 R133 T198 C207	W122-C129 VanDerWaalsContact CZ2-CA 3.49Å; W122-C129 HydrophobicContact CZ2-CB 4.08Å; W122-C129 VanDerWaalsContact CZ2-N 3.3Å; G125-C129 PolarHBondContact O-N 3.44Å; E126-C129 WeakPolarHBondContact O-CB 3.47Å; E126-C129 PolarHBondContact O-N 2.64Å; L127-C129 VanDerWaalsContact C-N 3.29Å; L127-C129 PolarHBondContact O-N 3.37Å; C129-L131 PolarHBondContact O-N 2.89Å; C129-V132 PolarHBondContact O-N 3.36Å; C129-R133 VanDerWaalsContact O-CG 3.3Å; C129-R133 WeakPolarHBondContact O-CG 3.32Å; C129-R133 PolarHBondContact O-N 3.08Å; C129-T198 HydrophobicContact CB-CG2 3.92Å; C129-C207 VanDerWaalsContact CA-SG 3.5Å; C129-C207 HydrophobicContact CB-CB 3.8Å; C129-C207 WeakPolarHBondContact CB-SG 3.38Å; C129-C207 VanDerWaalsContact SG-CA 3.56Å; C129-C207 WeakPolarHBondContact SG-CB 3.33Å; C129-C207 CovalentContact SG-SG 2.03Å; C129-C207 PolarHBondContact SG-SG 3.47Å
130	K	97.7	Very high	97	Very high	44 Å²	44	34.9 Å²	34.9	19%	0.191	18%	0.183	C	C	.	.	H	α-helix	trans	-59	-47.3	178.2	-71.7	175.1	178.7	176.1	0	112.4	E126 L127 V132 R133 F134 F193 A196	E126-K130 HydrophobicContact CG-CD 4.36Å; E126-K130 PolarHBondContact O-N 2.93Å; E126-K130 WeakPolarHBondContact OE1-CE 3.12Å; E126-K130 IonicContact OE1-NZ 3.87Å; E126-K130 PolarHBondContact OE1-NZ 3.37Å; L127-K130 PolarHBondContact O-N 3.3Å; K130-V132 PolarHBondContact O-N 3.24Å; K130-R133 PolarHBondContact O-N 2.94Å; K130-F134 WeakPolarHBondContact O-CB 3.31Å; K130-F134 PolarHBondContact O-N 2.87Å; K130-F193 HydrophobicContact CB-CD1 3.74Å; K130-F193 HydrophobicContact CB-CE1 4.04Å; K130-F193 HydrophobicContact CD-CD1 4.2Å; K130-F193 VanDerWaalsContact CD-O 3.31Å; K130-F193 WeakPolarHBondContact CD-O 3.34Å; K130-F193 WeakPolarHBondContact CE-O 3.47Å; K130-F193 HydrophobicContact CG-CD1 4.45Å; K130-F193 PolarHBondContact NZ-O 3.27Å; K130-A196 WeakPolarHBondContact CE-O 3.47Å; K130-A196 HydrophobicContact CG-CB 4.18Å; K130-A196 VanDerWaalsContact CG-O 3.27Å; K130-A196 WeakPolarHBondContact CG-O 3.49Å
131	L	97.6	Very high	97.1	Very high	84 Å²	84	33.4 Å²	33.4	44%	0.44	18%	0.175	S	C	.	.	H	α-helix	trans	-60.6	-44.7	179.8	-74.7	171.7	0	0	0	112.2	L127 A128 C129 F134 Q135 F193	L127-L131 HydrophobicContact CD1-CD1 4.17Å; L127-L131 HydrophobicContact CD1-CG 4.18Å; L127-L131 HydrophobicContact CG-CD1 3.93Å; L127-L131 HydrophobicContact CG-CG 4.39Å; L127-L131 WeakPolarHBondContact O-CB 3.47Å; L127-L131 WeakPolarHBondContact O-CG 3.03Å; L127-L131 PolarHBondContact O-N 3.37Å; A128-L131 PolarHBondContact O-N 3.15Å; C129-L131 PolarHBondContact O-N 2.89Å; L131-F134 PolarHBondContact O-N 3.11Å; L131-Q135 VanDerWaalsContact O-CB 3.23Å; L131-Q135 WeakPolarHBondContact O-CB 3.37Å; L131-Q135 PolarHBondContact O-N 3.11Å; L131-F193 HydrophobicContact CD2-CE1 4.02Å; L131-F193 HydrophobicContact CD2-CZ 3.89Å; L131-F193 HydrophobicContact CG-CE1 4.45Å
132	V	97.6	Very high	97.2	Very high	4 Å²	4	29 Å²	29	2%	0.024	16%	0.158	C	C	.	.	H	α-helix	trans	-67.4	-39.2	179.6	170.7	0	0	0	0	111.6	L111 L112 W122 A128 C129 K130 F136	L111-V132 HydrophobicContact CB-CG2 4.16Å; L111-V132 HydrophobicContact CD1-CG2 3.51Å; L111-V132 HydrophobicContact CG-CG2 4.47Å; L112-V132 HydrophobicContact CD1-CG1 3.71Å; L112-V132 HydrophobicContact CD2-CG1 3.46Å; L112-V132 VanDerWaalsContact CD2-CG1 3.46Å; L112-V132 HydrophobicContact CG-CG1 3.42Å; L112-V132 VanDerWaalsContact CG-CG1 3.42Å; W122-V132 HydrophobicContact CH2-CB 4.35Å; W122-V132 HydrophobicContact CH2-CG2 4.08Å; A128-V132 WeakPolarHBondContact O-CB 3.47Å; A128-V132 VanDerWaalsContact O-CG2 3.27Å; A128-V132 WeakPolarHBondContact O-CG2 3.43Å; A128-V132 PolarHBondContact O-N 3.37Å; C129-V132 PolarHBondContact O-N 3.36Å; K130-V132 PolarHBondContact O-N 3.24Å; V132-F136 PolarHBondContact O-N 3.28Å; V132-F136 VanDerWaalsContact O-N 3.09Å
133	R	96.9	Very high	97.1	Very high	1 Å²	1	29 Å²	29	0%	0.004	16%	0.158	C	C	.	.	H	α-helix	trans	-65.7	-44.7	173.6	-60.6	-40.9	170.9	159.9	-1.1	111.6	C129 K130 Q135 F136 Y137 T192 A196 C207 Y208 D209 R319	C129-R133 VanDerWaalsContact O-CG 3.3Å; C129-R133 WeakPolarHBondContact O-CG 3.32Å; C129-R133 PolarHBondContact O-N 3.08Å; K130-R133 PolarHBondContact O-N 2.94Å; R133-Q135 VanDerWaalsContact C-N 3.33Å; R133-Q135 PolarHBondContact O-N 3.48Å; R133-F136 PolarHBondContact O-N 3.04Å; R133-Y137 VanDerWaalsContact O-CD2 3.23Å; R133-Y137 WeakPolarHBondContact O-CD2 3.22Å; R133-Y137 PolarHBondContact O-N 3.26Å; R133-Y137 VanDerWaalsContact O-N 3.14Å; R133-T192 HydrophobicContact CB-CG2 3.74Å; R133-A196 HydrophobicContact CB-CB 3.9Å; R133-A196 HydrophobicContact CG-CB 3.82Å; R133-C207 PolarHBondContact NE-SG 3.39Å; R133-C207 PolarHBondContact NH2-O 2.95Å; R133-Y208 PolarHBondContact NE-O 3.21Å; R133-D209 IonicContact CZ-OD1 3.99Å; R133-D209 IonicContact NH1-OD1 3.2Å; R133-D209 PolarHBondContact NH1-OD1 3.28Å; R133-D209 IonicContact NH2-OD1 2.93Å; R133-D209 PolarHBondContact NH2-OD1 3.49Å; R133-R319 VanDerWaalsContact NH1-CZ 3.3Å
134	F	97.2	Very high	97	Very high	27 Å²	27	26.2 Å²	26.2	12%	0.118	14%	0.14	C	C	.	.	H	α-helix	trans	-60.4	-43.8	176.9	175.4	-98.2	0	0	0	111.7	K130 L131 F136 Y137 S138 L186 C189 T192 F193	K130-F134 WeakPolarHBondContact O-CB 3.31Å; K130-F134 PolarHBondContact O-N 2.87Å; L131-F134 PolarHBondContact O-N 3.11Å; F134-F136 PolarHBondContact O-N 2.95Å; F134-Y137 PolarHBondContact O-N 3.11Å; F134-S138 WeakPolarHBondContact CE1-OG 3.38Å; F134-S138 WeakPolarHBondContact CZ-OG 3.44Å; F134-S138 VanDerWaalsContact O-CB 3.25Å; F134-S138 WeakPolarHBondContact O-CB 3.16Å; F134-S138 PolarHBondContact O-N 2.96Å; F134-S138 PolarHBondContact O-OG 3.49Å; F134-L186 HydrophobicContact CE1-CD2 4.23Å; F134-L186 HydrophobicContact CZ-CD2 3.62Å; F134-C189 HydrophobicContact CD2-CB 3.76Å; F134-C189 HydrophobicContact CE2-CB 3.49Å; F134-C189 VanDerWaalsContact CE2-CB 3.49Å; F134-C189 HydrophobicContact CZ-CB 4.39Å; F134-T192 HydrophobicContact CB-CG2 4.32Å; F134-F193 HydrophobicContact CB-CE2 3.94Å; F134-F193 HydrophobicContact CB-CZ 4.1Å; F134-F193 HydrophobicContact CD1-CE2 4.01Å; F134-F193 HydrophobicContact CD1-CZ 4.21Å; F134-F193 AromaticContact CD2-CD2 3.92Å; F134-F193 HydrophobicContact CD2-CD2 3.92Å; F134-F193 AromaticContact CD2-CE2 3.41Å; F134-F193 HydrophobicContact CD2-CE2 3.41Å; F134-F193 VanDerWaalsContact CD2-CE2 3.41Å; F134-F193 HydrophobicContact CD2-CZ 4.31Å; F134-F193 HydrophobicContact CE1-CE2 4.37Å; F134-F193 HydrophobicContact CE2-CD2 4.4Å; F134-F193 AromaticContact CE2-CE2 3.81Å; F134-F193 HydrophobicContact CE2-CE2 3.81Å; F134-F193 HydrophobicContact CG-CD2 4.32Å; F134-F193 AromaticContact CG-CE2 3.5Å; F134-F193 HydrophobicContact CG-CE2 3.5Å; F134-F193 VanDerWaalsContact CG-CE2 3.5Å; F134-F193 AromaticContact CG-CZ 3.94Å; F134-F193 HydrophobicContact CG-CZ 3.94Å; F134-F193 HydrophobicContact CZ-CE2 4.26Å
135	Q	97.1	Very high	96.9	Very high	35 Å²	35	23.8 Å²	23.8	16%	0.164	13%	0.13	C	C	.	.	H	α-helix	trans	-65	-39.7	179.7	-170.7	62.8	42.8	0	0	111.7	L104 Y105 L131 R133 S138 N139	L104-Q135 WeakPolarHBondContact O-CG 3.18Å; Y105-Q135 HydrophobicContact CD2-CG 4.23Å; L131-Q135 VanDerWaalsContact O-CB 3.23Å; L131-Q135 WeakPolarHBondContact O-CB 3.37Å; L131-Q135 PolarHBondContact O-N 3.11Å; R133-Q135 VanDerWaalsContact C-N 3.33Å; R133-Q135 PolarHBondContact O-N 3.48Å; Q135-S138 PolarHBondContact O-N 2.91Å; Q135-N139 VanDerWaalsContact O-CB 3.3Å; Q135-N139 WeakPolarHBondContact O-CB 3.5Å; Q135-N139 PolarHBondContact O-N 3.24Å
136	F	96.8	Very high	96.8	Very high	3 Å²	3	22 Å²	22	1%	0.013	11%	0.112	C	C	.	.	H	α-helix	trans	-58.4	-50.8	172.8	172.6	-96.4	0	0	0	111.9	Y105 V132 R133 F134 L140 F287 R319 A322	Y105-F136 HydrophobicContact CD2-CB 4.36Å; Y105-F136 HydrophobicContact CE2-CB 3.89Å; Y105-F136 AromaticContact CE2-CD2 3.85Å; Y105-F136 HydrophobicContact CE2-CD2 3.85Å; Y105-F136 HydrophobicContact CE2-CG 4.38Å; Y105-F136 AromaticContact CZ-CD2 3.8Å; Y105-F136 WeakPolarHBondContact OH-CD2 3.41Å; V132-F136 PolarHBondContact O-N 3.28Å; V132-F136 VanDerWaalsContact O-N 3.09Å; R133-F136 PolarHBondContact O-N 3.04Å; F134-F136 PolarHBondContact O-N 2.95Å; F136-L140 HydrophobicContact CE1-CD2 4.41Å; F136-L140 WeakPolarHBondContact O-CB 3.42Å; F136-L140 PolarHBondContact O-N 2.94Å; F136-F287 HydrophobicContact CE1-CE1 4.15Å; F136-F287 AromaticContact CE1-CE2 3.93Å; F136-F287 HydrophobicContact CE1-CE2 3.93Å; F136-F287 AromaticContact CE1-CZ 3.51Å; F136-F287 HydrophobicContact CE1-CZ 3.51Å; F136-F287 HydrophobicContact CZ-CD2 4.32Å; F136-F287 HydrophobicContact CZ-CE1 4.29Å; F136-F287 AromaticContact CZ-CE2 3.72Å; F136-F287 HydrophobicContact CZ-CE2 3.72Å; F136-F287 AromaticContact CZ-CZ 3.71Å; F136-F287 HydrophobicContact CZ-CZ 3.71Å; F136-R319 HydrophobicContact CE2-CG 4.28Å; F136-R319 HydrophobicContact CZ-CG 4.04Å; F136-A322 HydrophobicContact CE2-CB 4.14Å; F136-A322 HydrophobicContact CZ-CB 4.04Å
137	Y	97.1	Very high	96.5	Very high	3 Å²	3	17.8 Å²	17.8	1%	0.012	9%	0.092	C	C	.	.	H	α-helix	trans	-68.7	-38.5	179.6	-75.3	-65.3	0	0	0	112.7	R133 F134 L140 H141 T192 L210 L226 F287	R133-Y137 VanDerWaalsContact O-CD2 3.23Å; R133-Y137 WeakPolarHBondContact O-CD2 3.22Å; R133-Y137 PolarHBondContact O-N 3.26Å; R133-Y137 VanDerWaalsContact O-N 3.14Å; F134-Y137 PolarHBondContact O-N 3.11Å; Y137-L140 HydrophobicContact CD1-CD2 4.5Å; Y137-L140 PolarHBondContact O-N 3.16Å; Y137-H141 WeakPolarHBondContact O-CB 3.25Å; Y137-H141 PolarHBondContact O-CD2 2.68Å; Y137-H141 PolarHBondContact O-N 2.88Å; Y137-T192 HydrophobicContact CD2-CG2 4.23Å; Y137-L210 WeakPolarHBondContact OH-CD2 3.42Å; Y137-L226 HydrophobicContact CD1-CD2 3.83Å; Y137-L226 HydrophobicContact CE1-CD2 4.14Å; Y137-L226 HydrophobicContact CG-CD2 4.3Å; Y137-F287 HydrophobicContact CE1-CE1 4.43Å; Y137-F287 HydrophobicContact CE1-CZ 4.2Å
138	S	97.1	Very high	96.3	Very high	4 Å²	4	13.3 Å²	13.3	3%	0.028	7%	0.069	C	C	.	.	H	α-helix	trans	-64.7	-41.8	178.1	-60.7	0	0	0	0	111.6	F134 Q135 G142 V185	F134-S138 WeakPolarHBondContact CE1-OG 3.38Å; F134-S138 WeakPolarHBondContact CZ-OG 3.44Å; F134-S138 VanDerWaalsContact O-CB 3.25Å; F134-S138 WeakPolarHBondContact O-CB 3.16Å; F134-S138 PolarHBondContact O-N 2.96Å; F134-S138 PolarHBondContact O-OG 3.49Å; Q135-S138 PolarHBondContact O-N 2.91Å; S138-G142 WeakPolarHBondContact O-CA 3.25Å; S138-G142 PolarHBondContact O-N 3.13Å; S138-V185 WeakPolarHBondContact O-CG1 3.34Å
139	N	97.3	Very high	96	Very high	3 Å²	3	13.4 Å²	13.4	2%	0.016	7%	0.069	C	C	.	.	H	α-helix	trans	-64.8	-48.2	173.2	170.6	-91.8	0	0	0	111.7	A101 D102 Y105 Q135 H141 G142 S143 N325	A101-N139 VanDerWaalsContact C-ND2 3.27Å; A101-N139 PolarHBondContact O-ND2 3.18Å; A101-N139 VanDerWaalsContact O-ND2 3.11Å; D102-N139 VanDerWaalsContact CA-ND2 3.26Å; D102-N139 WeakPolarHBondContact CA-ND2 3.27Å; D102-N139 PolarHBondContact N-ND2 3.41Å; D102-N139 PolarHBondContact OD1-ND2 3.48Å; Y105-N139 HydrophobicContact CD1-CB 4.34Å; Y105-N139 HydrophobicContact CG-CB 3.91Å; Q135-N139 VanDerWaalsContact O-CB 3.3Å; Q135-N139 WeakPolarHBondContact O-CB 3.5Å; Q135-N139 PolarHBondContact O-N 3.24Å; N139-H141 PolarHBondContact O-N 3.11Å; N139-G142 PolarHBondContact O-N 3.28Å; N139-S143 WeakPolarHBondContact O-CB 3.25Å; N139-S143 PolarHBondContact O-N 3.16Å; N139-S143 PolarHBondContact O-OG 2.97Å; N139-N325 PolarHBondContact OD1-ND2 3.32Å; N139-N325 PolarHBondContact OD1-OD1 3.34Å
140	L	96.2	Very high	95.5	Very high	1 Å²	1	13.4 Å²	13.4	1%	0.005	7%	0.069	C	C	.	.	H	α-helix	trans	-56.4	-54.6	-179	176.1	62.3	0	0	0	111.7	F136 Y137 S143 I144 F284 F287 A322	F136-L140 HydrophobicContact CE1-CD2 4.41Å; F136-L140 WeakPolarHBondContact O-CB 3.42Å; F136-L140 PolarHBondContact O-N 2.94Å; Y137-L140 HydrophobicContact CD1-CD2 4.5Å; Y137-L140 PolarHBondContact O-N 3.16Å; L140-S143 PolarHBondContact O-N 3.17Å; L140-I144 HydrophobicContact CD1-CD1 4.18Å; L140-I144 HydrophobicContact CG-CD1 4.31Å; L140-I144 WeakPolarHBondContact O-CD1 3.34Å; L140-I144 WeakPolarHBondContact O-CG1 3.48Å; L140-I144 PolarHBondContact O-N 3.23Å; L140-F284 HydrophobicContact CD1-CD1 3.43Å; L140-F284 VanDerWaalsContact CD1-CD1 3.43Å; L140-F284 HydrophobicContact CD1-CE1 3.83Å; L140-F284 HydrophobicContact CD1-CG 4.44Å; L140-F287 HydrophobicContact CD2-CD1 3.55Å; L140-F287 HydrophobicContact CD2-CE1 3.27Å; L140-F287 HydrophobicContact CD2-CZ 4.24Å; L140-A322 HydrophobicContact CD1-CB 4.18Å
141	H	96.9	Very high	94.9	Very high	0 Å²	0	11.3 Å²	11.3	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-74.3	-36.1	-177.8	-67	-59.7	0	0	0	112.7	Y137 N139 S143 I144 L145 L226 G230 H288	Y137-H141 WeakPolarHBondContact O-CB 3.25Å; Y137-H141 PolarHBondContact O-CD2 2.68Å; Y137-H141 PolarHBondContact O-N 2.88Å; N139-H141 PolarHBondContact O-N 3.11Å; H141-S143 VanDerWaalsContact C-N 3.32Å; H141-S143 PolarHBondContact O-N 3.35Å; H141-I144 PolarHBondContact O-N 3.29Å; H141-L145 WeakPolarHBondContact O-CG 3.28Å; H141-L145 PolarHBondContact O-N 2.85Å; H141-L226 PolarHBondContact CE1-O 3.37Å; H141-L226 WeakPolarHBondContact NE2-CD1 3.41Å; H141-L226 VanDerWaalsContact NE2-CG 3.26Å; H141-L226 WeakPolarHBondContact NE2-CG 3.43Å; H141-G230 VanDerWaalsContact ND1-C 3.31Å; H141-G230 VanDerWaalsContact ND1-CA 3.33Å; H141-G230 WeakPolarHBondContact ND1-CA 3.28Å; H141-G230 PolarHBondContact ND1-O 3.15Å; H141-H288 AromaticContact CE1-CE1 3.61Å
142	G	97	Very high	94.4	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-59.5	-44.8	172.5	0	0	0	0	0	111.6	S138 N139 L145 F146	S138-G142 WeakPolarHBondContact O-CA 3.25Å; S138-G142 PolarHBondContact O-N 3.13Å; N139-G142 PolarHBondContact O-N 3.28Å; G142-L145 PolarHBondContact O-N 3.27Å; G142-F146 WeakPolarHBondContact O-CB 3.41Å; G142-F146 WeakPolarHBondContact O-CD2 3.49Å; G142-F146 WeakPolarHBondContact O-CG 3.39Å; G142-F146 PolarHBondContact O-N 3.24Å
143	S	95.6	Very high	93.7	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-62.5	-47.2	178.8	-57.7	0	0	0	0	111.9	N139 L140 H141 L145 F146 L147 N325	N139-S143 WeakPolarHBondContact O-CB 3.25Å; N139-S143 PolarHBondContact O-N 3.16Å; N139-S143 PolarHBondContact O-OG 2.97Å; L140-S143 PolarHBondContact O-N 3.17Å; H141-S143 VanDerWaalsContact C-N 3.32Å; H141-S143 PolarHBondContact O-N 3.35Å; S143-L145 VanDerWaalsContact C-N 3.33Å; S143-L145 PolarHBondContact O-N 2.89Å; S143-F146 PolarHBondContact O-N 3.33Å; S143-L147 VanDerWaalsContact O-CB 3.32Å; S143-L147 WeakPolarHBondContact O-CB 3.37Å; S143-L147 WeakPolarHBondContact O-CG 3.18Å; S143-L147 PolarHBondContact O-N 3.48Å; S143-N325 VanDerWaalsContact CB-ND2 3.32Å; S143-N325 WeakPolarHBondContact CB-ND2 3.22Å; S143-N325 PolarHBondContact OG-ND2 3.21Å; S143-N325 VanDerWaalsContact OG-ND2 3.1Å
144	I	95.5	Very high	92.9	Very high	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-56.4	-46.2	175.5	-70.6	162.7	0	0	0	111.4	L140 H141 T148 F231 P234 F280 F284	L140-I144 HydrophobicContact CD1-CD1 4.18Å; L140-I144 HydrophobicContact CG-CD1 4.31Å; L140-I144 WeakPolarHBondContact O-CD1 3.34Å; L140-I144 WeakPolarHBondContact O-CG1 3.48Å; L140-I144 PolarHBondContact O-N 3.23Å; H141-I144 PolarHBondContact O-N 3.29Å; I144-T148 WeakPolarHBondContact O-CB 3.28Å; I144-T148 PolarHBondContact O-N 3.45Å; I144-T148 PolarHBondContact O-OG1 3.49Å; I144-F231 HydrophobicContact CD1-CB 4.28Å; I144-F231 HydrophobicContact CD1-CD2 3.95Å; I144-P234 HydrophobicContact CG2-CB 3.47Å; I144-P234 VanDerWaalsContact CG2-CB 3.47Å; I144-P234 HydrophobicContact CG2-CG 3.95Å; I144-F280 HydrophobicContact CG1-CE1 4.28Å; I144-F280 HydrophobicContact CG2-CE1 4.02Å; I144-F280 HydrophobicContact CG2-CZ 4.02Å; I144-F284 HydrophobicContact CD1-CB 4.39Å; I144-F284 HydrophobicContact CD1-CD1 4.32Å; I144-F284 HydrophobicContact CD1-CD2 4.4Å; I144-F284 HydrophobicContact CD1-CG 4.12Å; I144-F284 HydrophobicContact CG1-CD1 4.16Å; I144-F284 HydrophobicContact CG1-CD2 3.67Å; I144-F284 HydrophobicContact CG1-CE1 4.28Å; I144-F284 HydrophobicContact CG1-CE2 3.81Å; I144-F284 HydrophobicContact CG1-CG 3.87Å; I144-F284 HydrophobicContact CG1-CZ 4.13Å
145	L	95.8	Very high	92.1	Very high	29 Å²	29	13.7 Å²	13.7	15%	0.152	7%	0.069	C	C	.	.	H	α-helix	trans	-70.3	-41.1	-179.4	-70.4	174.6	0	0	0	112.3	H141 G142 S143 T148 C149 V181 V184 V185 P234	H141-L145 WeakPolarHBondContact O-CG 3.28Å; H141-L145 PolarHBondContact O-N 2.85Å; G142-L145 PolarHBondContact O-N 3.27Å; S143-L145 VanDerWaalsContact C-N 3.33Å; S143-L145 PolarHBondContact O-N 2.89Å; L145-T148 WeakPolarHBondContact O-CB 3.38Å; L145-T148 PolarHBondContact O-N 2.83Å; L145-C149 PolarHBondContact O-N 3.46Å; L145-C149 PolarHBondContact O-SG 3.33Å; L145-V181 HydrophobicContact CB-CG1 3.68Å; L145-V181 HydrophobicContact CB-CG2 4.37Å; L145-V181 HydrophobicContact CD1-CG1 4.13Å; L145-V184 HydrophobicContact CD1-CG1 4.06Å; L145-V185 HydrophobicContact CD1-CG2 3.79Å; L145-P234 HydrophobicContact CD2-CB 4.25Å; L145-P234 HydrophobicContact CD2-CG 3.71Å
146	F	94.6	Very high	91.3	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-66.4	-39.3	175.9	-73.4	-54.5	0	0	0	112.4	Y94 N97 L98 G142 S143 T148 C149 I150 C178 V181 W182	Y94-F146 HydrophobicContact CD1-CD1 4.47Å; N97-F146 HydrophobicContact CB-CD1 4.07Å; N97-F146 HydrophobicContact CB-CD2 4.34Å; N97-F146 HydrophobicContact CB-CE1 3.49Å; N97-F146 VanDerWaalsContact CB-CE1 3.49Å; N97-F146 HydrophobicContact CB-CE2 3.81Å; N97-F146 HydrophobicContact CB-CG 4.5Å; N97-F146 HydrophobicContact CB-CZ 3.38Å; L98-F146 HydrophobicContact CB-CB 4.18Å; L98-F146 HydrophobicContact CB-CD2 4.47Å; L98-F146 HydrophobicContact CD1-CB 4.29Å; G142-F146 WeakPolarHBondContact O-CB 3.41Å; G142-F146 WeakPolarHBondContact O-CD2 3.49Å; G142-F146 WeakPolarHBondContact O-CG 3.39Å; G142-F146 PolarHBondContact O-N 3.24Å; S143-F146 PolarHBondContact O-N 3.33Å; F146-T148 VanDerWaalsContact C-N 3.3Å; F146-T148 PolarHBondContact O-N 3.43Å; F146-C149 PolarHBondContact O-N 2.83Å; F146-I150 VanDerWaalsContact O-CG1 3.26Å; F146-I150 WeakPolarHBondContact O-CG1 3.33Å; F146-I150 PolarHBondContact O-N 3.18Å; F146-C178 HydrophobicContact CE1-CB 4.07Å; F146-V181 HydrophobicContact CD1-CG1 4.16Å; F146-V181 HydrophobicContact CD2-CG1 4.41Å; F146-V181 HydrophobicContact CE1-CB 3.94Å; F146-V181 HydrophobicContact CE1-CG1 3.71Å; F146-V181 HydrophobicContact CE1-CG2 4.42Å; F146-V181 HydrophobicContact CE2-CG1 3.99Å; F146-V181 HydrophobicContact CG-CG1 4.45Å; F146-V181 HydrophobicContact CZ-CB 4.1Å; F146-V181 HydrophobicContact CZ-CG1 3.58Å; F146-W182 HydrophobicContact CE2-CZ2 4.29Å; F146-W182 AromaticContact CZ-NE1 3.7Å
147	L	90.7	Very high	90.3	Very high	1 Å²	1	15.3 Å²	15.3	1%	0.005	9%	0.086	C	C	.	.	H	α-helix	trans	-63.5	-37.7	172.6	-70.9	170.7	0	0	0	111.5	L98 S143 I150 S151 V276 V279 F280 F284 F333	L98-L147 HydrophobicContact CD2-CD2 4.16Å; S143-L147 VanDerWaalsContact O-CB 3.32Å; S143-L147 WeakPolarHBondContact O-CB 3.37Å; S143-L147 WeakPolarHBondContact O-CG 3.18Å; S143-L147 PolarHBondContact O-N 3.48Å; L147-I150 PolarHBondContact O-N 2.9Å; L147-S151 WeakPolarHBondContact O-CB 3.34Å; L147-S151 PolarHBondContact O-N 3.17Å; L147-S151 PolarHBondContact O-OG 3.17Å; L147-V276 HydrophobicContact CD2-CG2 4.43Å; L147-V279 HydrophobicContact CD1-CG1 3.99Å; L147-F280 HydrophobicContact CB-CE2 4.36Å; L147-F284 HydrophobicContact CD1-CE2 3.61Å; L147-F284 HydrophobicContact CD1-CZ 4Å; L147-F333 HydrophobicContact CD2-CE2 3.81Å; L147-F333 HydrophobicContact CD2-CZ 3.6Å
148	T	91.9	Very high	89.1	Confident	21 Å²	21	16.7 Å²	16.7	13%	0.129	9%	0.094	C	C	.	.	H	α-helix	trans	-60.5	-49.3	170.9	-57.4	0	0	0	0	111.1	I144 L145 F146 I150 S151 V152 V238	I144-T148 WeakPolarHBondContact O-CB 3.28Å; I144-T148 PolarHBondContact O-N 3.45Å; I144-T148 PolarHBondContact O-OG1 3.49Å; L145-T148 WeakPolarHBondContact O-CB 3.38Å; L145-T148 PolarHBondContact O-N 2.83Å; F146-T148 VanDerWaalsContact C-N 3.3Å; F146-T148 PolarHBondContact O-N 3.43Å; T148-I150 VanDerWaalsContact C-N 3.34Å; T148-I150 PolarHBondContact O-N 2.86Å; T148-S151 WeakPolarHBondContact O-CB 3.33Å; T148-S151 PolarHBondContact O-N 3Å; T148-S151 VanDerWaalsContact O-N 3.14Å; T148-V152 HydrophobicContact CG2-CG2 4.36Å; T148-V152 WeakPolarHBondContact O-CG2 3.49Å; T148-V152 PolarHBondContact O-N 2.98Å; T148-V238 HydrophobicContact CG2-CG2 3.94Å; T148-V238 WeakPolarHBondContact OG1-CG2 3.22Å
149	C	91.6	Very high	87.8	Confident	22 Å²	22	17.7 Å²	17.7	15%	0.149	10%	0.1	C	C	.	.	H	α-helix	trans	-59.6	-42.1	176.8	-66.6	0	0	0	0	112.6	Y94 L145 F146 S151 N153	Y94-C149 HydrophobicContact CD1-CB 3.73Å; Y94-C149 HydrophobicContact CE1-CB 3.74Å; Y94-C149 HydrophobicContact CG-CB 4.15Å; L145-C149 PolarHBondContact O-N 3.46Å; L145-C149 PolarHBondContact O-SG 3.33Å; F146-C149 PolarHBondContact O-N 2.83Å; C149-S151 VanDerWaalsContact C-N 3.33Å; C149-S151 PolarHBondContact O-N 3.5Å; C149-N153 WeakPolarHBondContact O-CB 3.37Å; C149-N153 PolarHBondContact O-N 3.43Å
150	I	87.5	Confident	86.6	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-60.4	-45.5	175.3	-70.2	165.1	0	0	0	110.1	Y94 M95 L98 F146 L147 T148 R154 M272 F333	Y94-I150 HydrophobicContact CD2-CG1 4.38Å; Y94-I150 HydrophobicContact CG-CG1 4.26Å; M95-I150 HydrophobicContact CG-CD1 4.04Å; L98-I150 HydrophobicContact CD2-CD1 4.45Å; F146-I150 VanDerWaalsContact O-CG1 3.26Å; F146-I150 WeakPolarHBondContact O-CG1 3.33Å; F146-I150 PolarHBondContact O-N 3.18Å; L147-I150 PolarHBondContact O-N 2.9Å; T148-I150 VanDerWaalsContact C-N 3.34Å; T148-I150 PolarHBondContact O-N 2.86Å; I150-R154 WeakPolarHBondContact O-CB 3.49Å; I150-R154 WeakPolarHBondContact O-CG 3.5Å; I150-R154 PolarHBondContact O-N 3.47Å; I150-R154 VanDerWaalsContact O-N 3.11Å; I150-M272 HydrophobicContact CG2-SD 4.15Å; I150-F333 HydrophobicContact CD1-CE1 4.49Å; I150-F333 HydrophobicContact CD1-CE2 4.44Å; I150-F333 HydrophobicContact CD1-CZ 3.86Å; I150-F333 HydrophobicContact CG2-CE1 4.28Å; I150-F333 HydrophobicContact CG2-CZ 4.44Å
151	S	85.8	Confident	85.2	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-62.3	-48.1	179.6	-58.8	0	0	0	0	112.1	L147 T148 C149 R154 Y155 Y242	L147-S151 WeakPolarHBondContact O-CB 3.34Å; L147-S151 PolarHBondContact O-N 3.17Å; L147-S151 PolarHBondContact O-OG 3.17Å; T148-S151 WeakPolarHBondContact O-CB 3.33Å; T148-S151 PolarHBondContact O-N 3Å; T148-S151 VanDerWaalsContact O-N 3.14Å; C149-S151 VanDerWaalsContact C-N 3.33Å; C149-S151 PolarHBondContact O-N 3.5Å; S151-R154 WeakPolarHBondContact O-CB 3.32Å; S151-R154 PolarHBondContact O-N 2.85Å; S151-Y155 PolarHBondContact O-N 2.91Å; S151-Y242 WeakPolarHBondContact CB-OH 3.06Å; S151-Y242 PolarHBondContact OG-OH 2.79Å
152	V	85.8	Confident	83.5	Confident	51 Å²	51	32.3 Å²	32.3	31%	0.309	17%	0.171	S	C	.	.	H	α-helix	trans	-64.8	-46.7	178	172.2	0	0	0	0	111.3	T148 R154 Y155 I156	T148-V152 HydrophobicContact CG2-CG2 4.36Å; T148-V152 WeakPolarHBondContact O-CG2 3.49Å; T148-V152 PolarHBondContact O-N 2.98Å; V152-R154 PolarHBondContact O-N 2.9Å; V152-R154 VanDerWaalsContact O-N 3.16Å; V152-Y155 WeakPolarHBondContact O-CB 3.19Å; V152-Y155 PolarHBondContact O-N 3.26Å; V152-I156 HydrophobicContact CG1-CD1 3.8Å; V152-I156 HydrophobicContact CG1-CG1 4.34Å; V152-I156 WeakPolarHBondContact O-CG1 3.45Å; V152-I156 PolarHBondContact O-N 3.1Å
153	N	84.3	Confident	81.8	Confident	16 Å²	16	33.1 Å²	33.1	9%	0.086	18%	0.177	C	C	.	.	H	α-helix	trans	-58.2	-32.7	178	170.4	73.7	0	0	0	112.1	R90 Y94 C149 G157	R90-N153 PolarHBondContact NH1-OD1 2.91Å; Y94-N153 HydrophobicContact CE2-CB 4.02Å; C149-N153 WeakPolarHBondContact O-CB 3.37Å; C149-N153 PolarHBondContact O-N 3.43Å; N153-G157 PolarHBondContact O-N 3.43Å; N153-G157 VanDerWaalsContact O-N 3.13Å
154	R	80	Confident	79.7	Confident	50 Å²	50	38.4 Å²	38.4	19%	0.189	21%	0.21	C	C	.	.	H	α-helix	trans	-78.3	-42.9	177.9	-74.7	-92	-155.5	-108.2	-0	112.6	N91 I150 S151 V152 I156 G157 I158 M272	N91-R154 PolarHBondContact ND2-NH2 2.99Å; N91-R154 PolarHBondContact OD1-NH2 3.38Å; I150-R154 WeakPolarHBondContact O-CB 3.49Å; I150-R154 WeakPolarHBondContact O-CG 3.5Å; I150-R154 PolarHBondContact O-N 3.47Å; I150-R154 VanDerWaalsContact O-N 3.11Å; S151-R154 WeakPolarHBondContact O-CB 3.32Å; S151-R154 PolarHBondContact O-N 2.85Å; V152-R154 PolarHBondContact O-N 2.9Å; V152-R154 VanDerWaalsContact O-N 3.16Å; R154-I156 VanDerWaalsContact C-N 3.35Å; R154-I156 PolarHBondContact O-N 3.31Å; R154-G157 PolarHBondContact O-N 3.47Å; R154-I158 WeakPolarHBondContact O-CD1 3.45Å; R154-I158 WeakPolarHBondContact O-CG1 3.34Å; R154-I158 PolarHBondContact O-N 3.05Å; R154-I158 VanDerWaalsContact O-N 3.11Å; R154-M272 HydrophobicContact CB-CE 3.39Å; R154-M272 HydrophobicContact CB-SD 3.83Å; R154-M272 VanDerWaalsContact CD-SD 3.57Å; R154-M272 HydrophobicContact CG-CE 3.66Å; R154-M272 HydrophobicContact CG-SD 3.34Å; R154-M272 WeakPolarHBondContact CG-SD 3.47Å; R154-M272 PolarHBondContact NE-SD 3.37Å; R154-M272 VanDerWaalsContact NE-SD 3.42Å
155	Y	80	Confident	77.9	Confident	49 Å²	49	44.7 Å²	44.7	19%	0.192	23%	0.234	C	C	.	.	H	α-helix	trans	-52.8	-52.8	170.2	169.7	-100.2	0	0	0	110.8	S151 V152 G157 I158 C159 C241 R244 M245	S151-Y155 PolarHBondContact O-N 2.91Å; V152-Y155 WeakPolarHBondContact O-CB 3.19Å; V152-Y155 PolarHBondContact O-N 3.26Å; Y155-G157 VanDerWaalsContact C-N 3.34Å; Y155-G157 PolarHBondContact O-N 3.35Å; Y155-I158 PolarHBondContact O-N 3.27Å; Y155-I158 VanDerWaalsContact O-N 3.16Å; Y155-C159 HydrophobicContact CD2-CB 4.34Å; Y155-C159 HydrophobicContact CE2-CB 3.97Å; Y155-C159 WeakPolarHBondContact CE2-SG 3.46Å; Y155-C159 WeakPolarHBondContact O-CB 3.15Å; Y155-C159 PolarHBondContact O-N 3.15Å; Y155-C241 HydrophobicContact CG-CB 4.48Å; Y155-R244 HydrophobicContact CE2-CB 3.74Å; Y155-M245 HydrophobicContact CD2-CB 4.32Å
156	I	79.5	Confident	76	Confident	37 Å²	37	45.1 Å²	45.1	19%	0.19	24%	0.236	C	C	.	.	H	α-helix	trans	-59.6	-44.4	178.6	-62.5	169.2	0	0	0	111	V152 R154 I158 H160 W165 L166	V152-I156 HydrophobicContact CG1-CD1 3.8Å; V152-I156 HydrophobicContact CG1-CG1 4.34Å; V152-I156 WeakPolarHBondContact O-CG1 3.45Å; V152-I156 PolarHBondContact O-N 3.1Å; R154-I156 VanDerWaalsContact C-N 3.35Å; R154-I156 PolarHBondContact O-N 3.31Å; I156-I158 PolarHBondContact O-N 3.09Å; I156-H160 HydrophobicContact CG2-CB 4.35Å; I156-H160 CarbonylContact O-C 3.26Å; I156-H160 VanDerWaalsContact O-C 3.26Å; I156-H160 WeakPolarHBondContact O-CA 3.34Å; I156-H160 PolarHBondContact O-N 3.38Å; I156-W165 HydrophobicContact CG2-CZ2 3.86Å; I156-L166 HydrophobicContact CG2-CD1 3.61Å
157	G	75.7	Confident	74.2	Confident	34 Å²	34	53.7 Å²	53.7	35%	0.351	27%	0.273	S	S	.	.	H	α-helix	trans	-66	-19.9	-179.1	0	0	0	0	0	115.2	N153 R154 Y155	N153-G157 PolarHBondContact O-N 3.43Å; N153-G157 VanDerWaalsContact O-N 3.13Å; R154-G157 PolarHBondContact O-N 3.47Å; Y155-G157 VanDerWaalsContact C-N 3.34Å; Y155-G157 PolarHBondContact O-N 3.35Å
158	I	71.7	Confident	72.5	Confident	33 Å²	33	61.3 Å²	61.3	17%	0.169	31%	0.309	C	S	.	.	H	α-helix	trans	-98.9	-48.3	179.4	-66.9	161.9	0	0	0	110.6	R154 Y155 I156 M245 L249 A269	R154-I158 WeakPolarHBondContact O-CD1 3.45Å; R154-I158 WeakPolarHBondContact O-CG1 3.34Å; R154-I158 PolarHBondContact O-N 3.05Å; R154-I158 VanDerWaalsContact O-N 3.11Å; Y155-I158 PolarHBondContact O-N 3.27Å; Y155-I158 VanDerWaalsContact O-N 3.16Å; I156-I158 PolarHBondContact O-N 3.09Å; I158-M245 HydrophobicContact CD1-SD 3.65Å; I158-L249 HydrophobicContact CG2-CD1 4.26Å; I158-A269 HydrophobicContact CD1-CB 3.41Å; I158-A269 VanDerWaalsContact CD1-CB 3.41Å
159	C	70.9	Confident	71.1	Confident	25 Å²	25	62.9 Å²	62.9	17%	0.169	33%	0.329	C	S	.	.	H	α-helix	trans	-85	-23.3	-173	-57.8	0	0	0	0	112.8	Y155 I248	Y155-C159 HydrophobicContact CD2-CB 4.34Å; Y155-C159 HydrophobicContact CE2-CB 3.97Å; Y155-C159 WeakPolarHBondContact CE2-SG 3.46Å; Y155-C159 WeakPolarHBondContact O-CB 3.15Å; Y155-C159 PolarHBondContact O-N 3.15Å; C159-I248 HydrophobicContact CB-CD1 3.98Å; C159-I248 WeakPolarHBondContact SG-CD1 3.41Å
160	H	72.4	Confident	70.4	Confident	91 Å²	91	62.1 Å²	62.1	42%	0.421	33%	0.325	S	S	.	.			trans	-133.9	61.9	-177.7	-55.6	-70	0	0	0	112	I156 F162 A163	I156-H160 HydrophobicContact CG2-CB 4.35Å; I156-H160 CarbonylContact O-C 3.26Å; I156-H160 VanDerWaalsContact O-C 3.26Å; I156-H160 WeakPolarHBondContact O-CA 3.34Å; I156-H160 PolarHBondContact O-N 3.38Å; H160-F162 PolarHBondContact O-N 3.37Å; H160-A163 HydrophobicContact CB-CB 4.44Å; H160-A163 PolarHBondContact O-N 3.12Å
161	P	66.2	Low	70.2	Confident	55 Å²	55	68.6 Å²	68.6	36%	0.357	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.1	-19	-172.6	27.8	-36.3	0	0	0	114.7	V260	P161-V260 HydrophobicContact CG-CG1 4.17Å
162	F	62.1	Low	70.2	Confident	164 Å²	164	79 Å²	79	72%	0.719	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.4	3.5	-179	-60.9	-71.4	0	0	0	114.3	H160 V164 V258	H160-F162 PolarHBondContact O-N 3.37Å; F162-V164 PolarHBondContact O-N 2.96Å; F162-V164 VanDerWaalsContact O-N 3.07Å; F162-V258 HydrophobicContact CE2-CG1 4.48Å
163	A	60.9	Low	70.3	Confident	17 Å²	17	80.4 Å²	80.4	14%	0.14	39%	0.393	C	S	.	.			trans	-62.6	114	178.1	0	0	0	0	0	110.7	H160 W165 L166	H160-A163 HydrophobicContact CB-CB 4.44Å; H160-A163 PolarHBondContact O-N 3.12Å; A163-W165 HydrophobicContact CB-CD2 3.86Å; A163-W165 HydrophobicContact CB-CE3 3.94Å; A163-W165 HydrophobicContact CB-CH2 3.64Å; A163-W165 HydrophobicContact CB-CZ2 3.54Å; A163-W165 HydrophobicContact CB-CZ3 3.84Å; A163-W165 PolarHBondContact O-N 2.95Å; A163-W165 VanDerWaalsContact O-N 3.14Å; A163-L166 HydrophobicContact CB-CD1 3.94Å; A163-L166 VanDerWaalsContact O-CB 3.32Å; A163-L166 WeakPolarHBondContact O-CB 3.48Å; A163-L166 PolarHBondContact O-N 3.01Å
164	V	51.2	Low	70.6	Confident	112 Å²	112	79.7 Å²	79.7	68%	0.679	39%	0.389	S	S	*	.	G	3₁₀ helix	trans	-57.7	-31.1	-169.5	178	0	0	0	0	113	F162 L166 K167	F162-V164 PolarHBondContact O-N 2.96Å; F162-V164 VanDerWaalsContact O-N 3.07Å; V164-L166 PolarHBondContact O-N 2.95Å; V164-L166 VanDerWaalsContact O-N 3.07Å; V164-K167 PolarHBondContact O-N 3.13Å
165	W	58.1	Low	71.2	Confident	132 Å²	132	81.7 Å²	81.7	50%	0.5	40%	0.396	S	S	.	.	G	3₁₀ helix	trans	-64.1	-11.8	175.5	71.5	75.6	0	0	0	114.4	I156 A163	I156-W165 HydrophobicContact CG2-CZ2 3.86Å; A163-W165 HydrophobicContact CB-CD2 3.86Å; A163-W165 HydrophobicContact CB-CE3 3.94Å; A163-W165 HydrophobicContact CB-CH2 3.64Å; A163-W165 HydrophobicContact CB-CZ2 3.54Å; A163-W165 HydrophobicContact CB-CZ3 3.84Å; A163-W165 PolarHBondContact O-N 2.95Å; A163-W165 VanDerWaalsContact O-N 3.14Å
166	L	55.2	Low	72	Confident	37 Å²	37	81.4 Å²	81.4	19%	0.194	41%	0.409	C	S	.	.	G	3₁₀ helix	trans	-74.7	-24.3	172.2	-95.2	85.2	0	0	0	113.4	R90 I156 A163 V164	R90-L166 VanDerWaalsContact NH2-CG 3.25Å; I156-L166 HydrophobicContact CG2-CD1 3.61Å; A163-L166 HydrophobicContact CB-CD1 3.94Å; A163-L166 VanDerWaalsContact O-CB 3.32Å; A163-L166 WeakPolarHBondContact O-CB 3.48Å; A163-L166 PolarHBondContact O-N 3.01Å; V164-L166 PolarHBondContact O-N 2.95Å; V164-L166 VanDerWaalsContact O-N 3.07Å
167	K	57.5	Low	72.7	Confident	181 Å²	181	82.7 Å²	82.7	79%	0.787	42%	0.415	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.7	-41.3	-171.2	-74.2	-177.2	176.4	-179.6	0	112.8	V164	V164-K167 PolarHBondContact O-N 3.13Å
168	E	54	Low	73.7	Confident	161 Å²	161	81 Å²	81	75%	0.752	40%	0.398	S	S	*	.	S	Bend	trans	-120.5	140.6	180	-82.5	164.5	172.2	0	0	111.8	G170	E168-G170 PolarHBondContact O-N 3.32Å
169	G	63.3	Low	75	Confident	54 Å²	54	82.1 Å²	82.1	56%	0.557	41%	0.412	S	S	*	.	S	Bend	trans	71.7	-13.6	175.7	0	0	0	0	0	117.2	R171 R172 M173	G169-R171 PolarHBondContact O-N 3.41Å; G169-R172 PolarHBondContact O-N 3.34Å; G169-M173 PolarHBondContact O-N 3.1Å
170	G	75.9	Confident	76.3	Confident	6 Å²	6	82.5 Å²	82.5	6%	0.062	42%	0.42	C	S	.	.	H	α-helix	trans	-57.3	-21.3	-174.2	0	0	0	0	0	116.1	R90 E168 A174	R90-G170 WeakPolarHBondContact CD-O 3.44Å; E168-G170 PolarHBondContact O-N 3.32Å; G170-A174 WeakPolarHBondContact O-CB 3.22Å; G170-A174 PolarHBondContact O-N 2.77Å
171	R	83.3	Confident	77.5	Confident	136 Å²	136	78.8 Å²	78.8	51%	0.513	40%	0.404	S	S	.	.	H	α-helix	trans	-72.9	-44.5	173.7	-170	174	60.4	-156.1	-3.1	112.5	I93 G169 M173 A174 W175	I93-R171 HydrophobicContact CD1-CG 3.62Å; G169-R171 PolarHBondContact O-N 3.41Å; R171-M173 VanDerWaalsContact C-N 3.32Å; R171-A174 PolarHBondContact O-N 3.28Å; R171-W175 PolarHBondContact O-N 2.67Å; R171-W175 VanDerWaalsContact O-N 3.13Å
172	R	86.7	Confident	79	Confident	217 Å²	217	78.7 Å²	78.7	82%	0.819	40%	0.396	S	S	*	.	H	α-helix	trans	-63.8	-43.1	176.9	-72.8	-177.3	-177.5	156.4	0.2	109.8	G169 A174 W175 G176	G169-R172 PolarHBondContact O-N 3.34Å; R172-A174 PolarHBondContact O-N 2.98Å; R172-W175 PolarHBondContact O-N 2.97Å; R172-G176 PolarHBondContact O-N 3.39Å
173	M	87.8	Confident	80.7	Confident	82 Å²	82	75.5 Å²	75.5	40%	0.404	39%	0.39	S	S	.	.	H	α-helix	trans	-59.3	-44.8	174.2	-172.5	-178.7	72.1	0	0	112.2	G169 R171 W175 G176 I177	G169-M173 PolarHBondContact O-N 3.1Å; R171-M173 VanDerWaalsContact C-N 3.32Å; M173-W175 VanDerWaalsContact C-N 3.34Å; M173-W175 PolarHBondContact O-N 2.96Å; M173-G176 PolarHBondContact O-N 3.38Å; M173-I177 HydrophobicContact CE-CD1 4.47Å; M173-I177 HydrophobicContact CG-CD1 3.97Å; M173-I177 HydrophobicContact CG-CG1 4.45Å; M173-I177 VanDerWaalsContact O-CG1 3.31Å; M173-I177 WeakPolarHBondContact O-CG1 3.27Å; M173-I177 PolarHBondContact O-N 3.42Å
174	A	90.3	Very high	82.5	Confident	0 Å²	0	78 Å²	78	0%	0	40%	0.404	C	S	.	.	H	α-helix	trans	-61.4	-39.9	177.8	0	0	0	0	0	112.9	R90 I93 G170 R171 R172 I177 C178	R90-A174 HydrophobicContact CB-CB 4.25Å; R90-A174 HydrophobicContact CG-CB 4.13Å; I93-A174 HydrophobicContact CB-CB 4.41Å; I93-A174 HydrophobicContact CD1-CB 3.93Å; I93-A174 HydrophobicContact CG2-CB 4.39Å; G170-A174 WeakPolarHBondContact O-CB 3.22Å; G170-A174 PolarHBondContact O-N 2.77Å; R171-A174 PolarHBondContact O-N 3.28Å; R172-A174 PolarHBondContact O-N 2.98Å; A174-I177 PolarHBondContact O-N 3.32Å; A174-C178 PolarHBondContact O-N 3.42Å; A174-C178 PolarHBondContact O-SG 2.68Å
175	W	93.5	Very high	84.7	Confident	92 Å²	92	72.7 Å²	72.7	35%	0.348	37%	0.372	S	S	.	.	H	α-helix	trans	-65	-43.2	172.4	-81.5	115.3	0	0	0	112.4	I93 L96 R171 R172 M173 I177 C178 A179	I93-W175 HydrophobicContact CD1-CG 4.33Å; I93-W175 HydrophobicContact CG1-CZ2 4.39Å; I93-W175 HydrophobicContact CG2-CD2 3.8Å; I93-W175 HydrophobicContact CG2-CE3 3.99Å; I93-W175 HydrophobicContact CG2-CG 4.25Å; I93-W175 HydrophobicContact CG2-CH2 4.43Å; I93-W175 HydrophobicContact CG2-CZ2 4.25Å; I93-W175 HydrophobicContact CG2-CZ3 4.3Å; L96-W175 HydrophobicContact CD2-CH2 3.96Å; L96-W175 HydrophobicContact CD2-CZ2 4.47Å; R171-W175 PolarHBondContact O-N 2.67Å; R171-W175 VanDerWaalsContact O-N 3.13Å; R172-W175 PolarHBondContact O-N 2.97Å; M173-W175 VanDerWaalsContact C-N 3.34Å; M173-W175 PolarHBondContact O-N 2.96Å; W175-I177 VanDerWaalsContact C-N 3.35Å; W175-I177 PolarHBondContact O-N 3.18Å; W175-C178 PolarHBondContact O-N 2.97Å; W175-A179 PolarHBondContact O-N 3.47Å
176	G	94.9	Very high	86.6	Confident	44 Å²	44	70.4 Å²	70.4	45%	0.454	37%	0.369	S	S	.	.	H	α-helix	trans	-59.6	-43	174.5	0	0	0	0	0	112.6	R172 M173 C178 A179 G180	R172-G176 PolarHBondContact O-N 3.39Å; M173-G176 PolarHBondContact O-N 3.38Å; G176-C178 PolarHBondContact O-N 3.09Å; G176-A179 PolarHBondContact O-N 3.47Å; G176-G180 PolarHBondContact O-N 2.82Å
177	I	95.3	Very high	88.7	Confident	63 Å²	63	76.2 Å²	76.2	32%	0.323	39%	0.393	S	S	.	.	H	α-helix	trans	-61.4	-44.7	174	-68.1	165.2	0	0	0	110.5	Y94 M173 A174 W175 A179 G180 V181	Y94-I177 HydrophobicContact CE1-CB 4.27Å; Y94-I177 HydrophobicContact CE1-CG2 3.86Å; Y94-I177 WeakPolarHBondContact OH-CD1 3.41Å; M173-I177 HydrophobicContact CE-CD1 4.47Å; M173-I177 HydrophobicContact CG-CD1 3.97Å; M173-I177 HydrophobicContact CG-CG1 4.45Å; M173-I177 VanDerWaalsContact O-CG1 3.31Å; M173-I177 WeakPolarHBondContact O-CG1 3.27Å; M173-I177 PolarHBondContact O-N 3.42Å; A174-I177 PolarHBondContact O-N 3.32Å; W175-I177 VanDerWaalsContact C-N 3.35Å; W175-I177 PolarHBondContact O-N 3.18Å; I177-A179 VanDerWaalsContact C-N 3.35Å; I177-A179 PolarHBondContact O-N 3.47Å; I177-G180 PolarHBondContact O-N 2.91Å; I177-V181 HydrophobicContact CG2-CG2 4.44Å; I177-V181 WeakPolarHBondContact O-CG2 3.25Å; I177-V181 PolarHBondContact O-N 3.49Å
178	C	96.9	Very high	90.6	Very high	0 Å²	0	68.6 Å²	68.6	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-63.5	-41.4	178.3	-66.1	0	0	0	0	112.1	Y94 N97 F146 A174 W175 G176 G180 V181 W182	Y94-C178 WeakPolarHBondContact CD1-SG 3.23Å; N97-C178 PolarHBondContact ND2-SG 2.94Å; N97-C178 VanDerWaalsContact ND2-SG 3.44Å; F146-C178 HydrophobicContact CE1-CB 4.07Å; A174-C178 PolarHBondContact O-N 3.42Å; A174-C178 PolarHBondContact O-SG 2.68Å; W175-C178 PolarHBondContact O-N 2.97Å; G176-C178 PolarHBondContact O-N 3.09Å; C178-G180 VanDerWaalsContact C-N 3.33Å; C178-V181 PolarHBondContact O-N 3.35Å; C178-W182 PolarHBondContact O-N 3.5Å
179	A	97.8	Very high	92.6	Very high	55 Å²	55	61 Å²	61	46%	0.455	33%	0.325	S	S	.	.	H	α-helix	trans	-60.9	-43.9	174.1	0	0	0	0	0	111.2	W175 G176 I177 V181 W182 V183	W175-A179 PolarHBondContact O-N 3.47Å; G176-A179 PolarHBondContact O-N 3.47Å; I177-A179 VanDerWaalsContact C-N 3.35Å; I177-A179 PolarHBondContact O-N 3.47Å; A179-V181 PolarHBondContact O-N 3.38Å; A179-W182 PolarHBondContact O-N 2.87Å; A179-V183 WeakPolarHBondContact O-CG2 3.2Å; A179-V183 PolarHBondContact O-N 3.48Å
180	G	98.1	Very high	94.2	Very high	33 Å²	33	60.6 Å²	60.6	34%	0.34	32%	0.317	S	S	.	.	H	α-helix	trans	-60	-43.6	173.9	0	0	0	0	0	113	G176 I177 C178 W182 V183 V184	G176-G180 PolarHBondContact O-N 2.82Å; I177-G180 PolarHBondContact O-N 2.91Å; C178-G180 VanDerWaalsContact C-N 3.33Å; G180-W182 PolarHBondContact O-N 3.49Å; G180-V183 PolarHBondContact O-N 2.96Å; G180-V184 WeakPolarHBondContact O-CG2 3.3Å; G180-V184 PolarHBondContact O-N 2.72Å
181	V	98	Very high	95.2	Very high	13 Å²	13	62.4 Å²	62.4	8%	0.079	33%	0.327	C	S	.	.	H	α-helix	trans	-59.1	-46.9	174.6	169.2	0	0	0	0	110.7	L145 F146 I177 C178 A179 V183 V184 V185	L145-V181 HydrophobicContact CB-CG1 3.68Å; L145-V181 HydrophobicContact CB-CG2 4.37Å; L145-V181 HydrophobicContact CD1-CG1 4.13Å; F146-V181 HydrophobicContact CD1-CG1 4.16Å; F146-V181 HydrophobicContact CD2-CG1 4.41Å; F146-V181 HydrophobicContact CE1-CB 3.94Å; F146-V181 HydrophobicContact CE1-CG1 3.71Å; F146-V181 HydrophobicContact CE1-CG2 4.42Å; F146-V181 HydrophobicContact CE2-CG1 3.99Å; F146-V181 HydrophobicContact CG-CG1 4.45Å; F146-V181 HydrophobicContact CZ-CB 4.1Å; F146-V181 HydrophobicContact CZ-CG1 3.58Å; I177-V181 HydrophobicContact CG2-CG2 4.44Å; I177-V181 WeakPolarHBondContact O-CG2 3.25Å; I177-V181 PolarHBondContact O-N 3.49Å; C178-V181 PolarHBondContact O-N 3.35Å; A179-V181 PolarHBondContact O-N 3.38Å; V181-V183 PolarHBondContact O-N 3.23Å; V181-V184 PolarHBondContact O-N 3.34Å; V181-V185 HydrophobicContact CG1-CG2 4.2Å; V181-V185 WeakPolarHBondContact O-CB 3.32Å; V181-V185 WeakPolarHBondContact O-CG2 3.4Å; V181-V185 PolarHBondContact O-N 3.24Å
182	W	98.3	Very high	95.8	Very high	53 Å²	53	56.1 Å²	56.1	20%	0.201	30%	0.304	C	S	.	.	H	α-helix	trans	-58.7	-47.5	175.8	-80	113.6	0	0	0	111.9	N97 I100 A101 F146 C178 A179 G180 V184 V185 L186	N97-W182 PolarHBondContact OD1-NE1 3.44Å; I100-W182 HydrophobicContact CG2-CZ2 4.3Å; A101-W182 HydrophobicContact CB-CH2 3.77Å; A101-W182 HydrophobicContact CB-CZ2 4.17Å; F146-W182 HydrophobicContact CE2-CZ2 4.29Å; F146-W182 AromaticContact CZ-NE1 3.7Å; C178-W182 PolarHBondContact O-N 3.5Å; A179-W182 PolarHBondContact O-N 2.87Å; G180-W182 PolarHBondContact O-N 3.49Å; W182-V184 VanDerWaalsContact C-N 3.33Å; W182-V184 PolarHBondContact O-N 3.48Å; W182-V185 PolarHBondContact O-N 2.88Å; W182-L186 WeakPolarHBondContact O-CB 3.48Å; W182-L186 WeakPolarHBondContact O-CG 3.35Å; W182-L186 PolarHBondContact O-N 3.14Å
183	V	98.5	Very high	96.2	Very high	98 Å²	98	49.3 Å²	49.3	59%	0.594	28%	0.28	S	S	*	.	H	α-helix	trans	-57.3	-46.3	176.8	170.7	0	0	0	0	111.5	A179 G180 V181 L186 F187	A179-V183 WeakPolarHBondContact O-CG2 3.2Å; A179-V183 PolarHBondContact O-N 3.48Å; G180-V183 PolarHBondContact O-N 2.96Å; V181-V183 PolarHBondContact O-N 3.23Å; V183-L186 PolarHBondContact O-N 2.91Å; V183-F187 VanDerWaalsContact O-CB 3.29Å; V183-F187 WeakPolarHBondContact O-CB 3.21Å; V183-F187 PolarHBondContact O-N 3.42Å
184	V	98.3	Very high	96.6	Very high	70 Å²	70	49.5 Å²	49.5	42%	0.424	29%	0.287	S	S	.	.	H	α-helix	trans	-61.7	-45.2	177.5	170.1	0	0	0	0	111.3	L145 G180 V181 W182 F187 L188	L145-V184 HydrophobicContact CD1-CG1 4.06Å; G180-V184 WeakPolarHBondContact O-CG2 3.3Å; G180-V184 PolarHBondContact O-N 2.72Å; V181-V184 PolarHBondContact O-N 3.34Å; W182-V184 VanDerWaalsContact C-N 3.33Å; W182-V184 PolarHBondContact O-N 3.48Å; V184-F187 PolarHBondContact O-N 2.92Å; V184-L188 HydrophobicContact CG1-CD1 3.81Å; V184-L188 HydrophobicContact CG1-CG 4.28Å; V184-L188 WeakPolarHBondContact O-CB 3.47Å; V184-L188 VanDerWaalsContact O-CG 3.28Å; V184-L188 WeakPolarHBondContact O-CG 3.21Å; V184-L188 PolarHBondContact O-N 3.2Å
185	V	98.1	Very high	96.8	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-62.8	-47.8	178.5	170.9	0	0	0	0	111	S138 L145 V181 W182 F187 L188 C189	S138-V185 WeakPolarHBondContact O-CG1 3.34Å; L145-V185 HydrophobicContact CD1-CG2 3.79Å; V181-V185 HydrophobicContact CG1-CG2 4.2Å; V181-V185 WeakPolarHBondContact O-CB 3.32Å; V181-V185 WeakPolarHBondContact O-CG2 3.4Å; V181-V185 PolarHBondContact O-N 3.24Å; W182-V185 PolarHBondContact O-N 2.88Å; V185-F187 VanDerWaalsContact C-N 3.31Å; V185-F187 PolarHBondContact O-N 3.5Å; V185-L188 PolarHBondContact O-N 2.86Å; V185-C189 VanDerWaalsContact O-CB 3.24Å; V185-C189 WeakPolarHBondContact O-CB 3.33Å; V185-C189 PolarHBondContact O-N 3.18Å; V185-C189 PolarHBondContact O-SG 2.88Å
186	L	97.8	Very high	96.9	Very high	84 Å²	84	46.6 Å²	46.6	44%	0.44	28%	0.276	S	S	.	.	H	α-helix	trans	-59.8	-44.6	178.2	-67.4	174.9	0	0	0	110.4	F134 W182 V183 C189 A190	F134-L186 HydrophobicContact CE1-CD2 4.23Å; F134-L186 HydrophobicContact CZ-CD2 3.62Å; W182-L186 WeakPolarHBondContact O-CB 3.48Å; W182-L186 WeakPolarHBondContact O-CG 3.35Å; W182-L186 PolarHBondContact O-N 3.14Å; V183-L186 PolarHBondContact O-N 2.91Å; L186-C189 PolarHBondContact O-N 3.3Å; L186-A190 WeakPolarHBondContact O-CA 3.34Å; L186-A190 VanDerWaalsContact O-CB 3.24Å; L186-A190 WeakPolarHBondContact O-CB 3.41Å; L186-A190 PolarHBondContact O-N 3.47Å
187	F	97.9	Very high	96.9	Very high	158 Å²	158	45.3 Å²	45.3	69%	0.693	26%	0.262	S	S	*	.	H	α-helix	trans	-62.1	-50.3	176.8	178.2	-98.8	0	0	0	112.4	V183 V184 V185 C189 A190	V183-F187 VanDerWaalsContact O-CB 3.29Å; V183-F187 WeakPolarHBondContact O-CB 3.21Å; V183-F187 PolarHBondContact O-N 3.42Å; V184-F187 PolarHBondContact O-N 2.92Å; V185-F187 VanDerWaalsContact C-N 3.31Å; V185-F187 PolarHBondContact O-N 3.5Å; F187-C189 VanDerWaalsContact C-N 3.29Å; F187-C189 PolarHBondContact O-N 3.41Å; F187-A190 PolarHBondContact O-N 3.25Å
188	L	97.1	Very high	97	Very high	22 Å²	22	44 Å²	44	12%	0.115	26%	0.256	C	S	.	.	H	α-helix	trans	-62.9	-35.6	178.7	-72.2	175.8	0	0	0	112.3	V184 V185 Y222 L226 L229	V184-L188 HydrophobicContact CG1-CD1 3.81Å; V184-L188 HydrophobicContact CG1-CG 4.28Å; V184-L188 WeakPolarHBondContact O-CB 3.47Å; V184-L188 VanDerWaalsContact O-CG 3.28Å; V184-L188 WeakPolarHBondContact O-CG 3.21Å; V184-L188 PolarHBondContact O-N 3.2Å; V185-L188 PolarHBondContact O-N 2.86Å; L188-Y222 VanDerWaalsContact O-CE2 3.24Å; L188-Y222 WeakPolarHBondContact O-CE2 3.49Å; L188-Y222 PolarHBondContact O-OH 3.24Å; L188-L226 HydrophobicContact CB-CD1 3.93Å; L188-L229 HydrophobicContact CD2-CB 4.05Å; L188-L229 HydrophobicContact CD2-CD1 3.88Å
189	C	97.5	Very high	96.9	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-89.4	-16.7	-176.8	-60	0	0	0	0	113.2	F134 V185 L186 F187 P191 T192	F134-C189 HydrophobicContact CD2-CB 3.76Å; F134-C189 HydrophobicContact CE2-CB 3.49Å; F134-C189 VanDerWaalsContact CE2-CB 3.49Å; F134-C189 HydrophobicContact CZ-CB 4.39Å; V185-C189 VanDerWaalsContact O-CB 3.24Å; V185-C189 WeakPolarHBondContact O-CB 3.33Å; V185-C189 PolarHBondContact O-N 3.18Å; V185-C189 PolarHBondContact O-SG 2.88Å; L186-C189 PolarHBondContact O-N 3.3Å; F187-C189 VanDerWaalsContact C-N 3.29Å; F187-C189 PolarHBondContact O-N 3.41Å; C189-P191 VanDerWaalsContact C-CD 3.46Å; C189-T192 WeakPolarHBondContact O-CB 3.43Å; C189-T192 PolarHBondContact O-N 3.46Å; C189-T192 PolarHBondContact O-OG1 3.48Å
190	A	97.3	Very high	96.6	Very high	47 Å²	47	47.8 Å²	47.8	39%	0.388	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.2	-42.6	-176.7	0	0	0	0	0	114.3	L186 F187 T192 F193	L186-A190 WeakPolarHBondContact O-CA 3.34Å; L186-A190 VanDerWaalsContact O-CB 3.24Å; L186-A190 WeakPolarHBondContact O-CB 3.41Å; L186-A190 PolarHBondContact O-N 3.47Å; F187-A190 PolarHBondContact O-N 3.25Å; A190-T192 PolarHBondContact O-N 2.8Å; A190-F193 PolarHBondContact O-N 2.8Å
191	P	96.6	Very high	96.2	Very high	43 Å²	43	50.6 Å²	50.6	28%	0.279	28%	0.277	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-14.7	178.1	-22.6	34.2	0	0	0	114.1	C189 F193 T194 F195 Y222	C189-P191 VanDerWaalsContact C-CD 3.46Å; P191-F193 PolarHBondContact O-N 2.81Å; P191-T194 WeakPolarHBondContact O-CB 3.25Å; P191-T194 PolarHBondContact O-N 2.85Å; P191-F195 HydrophobicContact CB-CD2 4.23Å; P191-F195 HydrophobicContact CB-CE2 4.21Å; P191-F195 VanDerWaalsContact O-CD2 3.25Å; P191-F195 WeakPolarHBondContact O-CD2 3.22Å; P191-F195 PolarHBondContact O-N 3.3Å; P191-F195 VanDerWaalsContact O-N 3.17Å; P191-Y222 HydrophobicContact CB-CD1 4.24Å; P191-Y222 HydrophobicContact CB-CD2 3.84Å; P191-Y222 HydrophobicContact CB-CE1 4.02Å; P191-Y222 HydrophobicContact CB-CE2 3.61Å; P191-Y222 HydrophobicContact CB-CG 4.15Å; P191-Y222 HydrophobicContact CG-CD2 3.91Å; P191-Y222 HydrophobicContact CG-CE2 3.55Å
192	T	95.6	Very high	95.6	Very high	5 Å²	5	59.1 Å²	59.1	3%	0.031	31%	0.308	C	S	.	.	H	α-helix	trans	-55	-34.8	170.9	-56.8	0	0	0	0	111.7	R133 F134 Y137 C189 A190 T194 F195 A196 Y222	R133-T192 HydrophobicContact CB-CG2 3.74Å; F134-T192 HydrophobicContact CB-CG2 4.32Å; Y137-T192 HydrophobicContact CD2-CG2 4.23Å; C189-T192 WeakPolarHBondContact O-CB 3.43Å; C189-T192 PolarHBondContact O-N 3.46Å; C189-T192 PolarHBondContact O-OG1 3.48Å; A190-T192 PolarHBondContact O-N 2.8Å; T192-T194 PolarHBondContact O-N 2.85Å; T192-F195 PolarHBondContact O-N 2.88Å; T192-A196 HydrophobicContact CG2-CB 4.01Å; T192-A196 WeakPolarHBondContact O-CB 3.34Å; T192-A196 PolarHBondContact O-N 2.91Å; T192-Y222 PolarHBondContact OG1-OH 3.36Å
193	F	95.8	Very high	95.2	Very high	73 Å²	73	64.2 Å²	64.2	32%	0.32	34%	0.338	S	S	.	.	H	α-helix	trans	-66.4	-22	176.5	-77.3	-83.9	0	0	0	113.7	K130 L131 F134 A190 P191	K130-F193 HydrophobicContact CB-CD1 3.74Å; K130-F193 HydrophobicContact CB-CE1 4.04Å; K130-F193 HydrophobicContact CD-CD1 4.2Å; K130-F193 VanDerWaalsContact CD-O 3.31Å; K130-F193 WeakPolarHBondContact CD-O 3.34Å; K130-F193 WeakPolarHBondContact CE-O 3.47Å; K130-F193 HydrophobicContact CG-CD1 4.45Å; K130-F193 PolarHBondContact NZ-O 3.27Å; L131-F193 HydrophobicContact CD2-CE1 4.02Å; L131-F193 HydrophobicContact CD2-CZ 3.89Å; L131-F193 HydrophobicContact CG-CE1 4.45Å; F134-F193 HydrophobicContact CB-CE2 3.94Å; F134-F193 HydrophobicContact CB-CZ 4.1Å; F134-F193 HydrophobicContact CD1-CE2 4.01Å; F134-F193 HydrophobicContact CD1-CZ 4.21Å; F134-F193 AromaticContact CD2-CD2 3.92Å; F134-F193 HydrophobicContact CD2-CD2 3.92Å; F134-F193 AromaticContact CD2-CE2 3.41Å; F134-F193 HydrophobicContact CD2-CE2 3.41Å; F134-F193 VanDerWaalsContact CD2-CE2 3.41Å; F134-F193 HydrophobicContact CD2-CZ 4.31Å; F134-F193 HydrophobicContact CE1-CE2 4.37Å; F134-F193 HydrophobicContact CE2-CD2 4.4Å; F134-F193 AromaticContact CE2-CE2 3.81Å; F134-F193 HydrophobicContact CE2-CE2 3.81Å; F134-F193 HydrophobicContact CG-CD2 4.32Å; F134-F193 AromaticContact CG-CE2 3.5Å; F134-F193 HydrophobicContact CG-CE2 3.5Å; F134-F193 VanDerWaalsContact CG-CE2 3.5Å; F134-F193 AromaticContact CG-CZ 3.94Å; F134-F193 HydrophobicContact CG-CZ 3.94Å; F134-F193 HydrophobicContact CZ-CE2 4.26Å; A190-F193 PolarHBondContact O-N 2.8Å; P191-F193 PolarHBondContact O-N 2.81Å
194	T	94.9	Very high	94.9	Very high	87 Å²	87	65.5 Å²	65.5	53%	0.534	33%	0.333	S	S	.	.	H	α-helix	trans	-86.3	-35.4	177.2	-53.8	0	0	0	0	111.9	P191 T192 R215	P191-T194 WeakPolarHBondContact O-CB 3.25Å; P191-T194 PolarHBondContact O-N 2.85Å; T192-T194 PolarHBondContact O-N 2.85Å; T194-R215 PolarHBondContact O-NH1 3.29Å
195	F	95.4	Very high	94.8	Very high	29 Å²	29	64.5 Å²	64.5	13%	0.127	33%	0.327	C	S	.	.	H	α-helix	trans	-97.8	-38.2	-172.4	-71	-69	0	0	0	114.5	P191 T192 A197 S211 D218 Y219 Y222	P191-F195 HydrophobicContact CB-CD2 4.23Å; P191-F195 HydrophobicContact CB-CE2 4.21Å; P191-F195 VanDerWaalsContact O-CD2 3.25Å; P191-F195 WeakPolarHBondContact O-CD2 3.22Å; P191-F195 PolarHBondContact O-N 3.3Å; P191-F195 VanDerWaalsContact O-N 3.17Å; T192-F195 PolarHBondContact O-N 2.88Å; F195-A197 PolarHBondContact O-N 2.88Å; F195-S211 WeakPolarHBondContact O-CA 3.34Å; F195-D218 HydrophobicContact CE1-CB 4.01Å; F195-D218 WeakPolarHBondContact CZ-O 3.39Å; F195-Y219 HydrophobicContact CB-CD2 3.58Å; F195-Y219 HydrophobicContact CB-CE2 4.03Å; F195-Y219 AromaticContact CD1-CD2 3.89Å; F195-Y219 HydrophobicContact CD1-CD2 3.89Å; F195-Y219 HydrophobicContact CD1-CG 4.44Å; F195-Y219 AromaticContact CD2-CD2 3.85Å; F195-Y219 HydrophobicContact CD2-CD2 3.85Å; F195-Y219 HydrophobicContact CD2-CE2 4.39Å; F195-Y219 HydrophobicContact CE2-CD2 4.48Å; F195-Y219 AromaticContact CG-CD2 3.53Å; F195-Y219 HydrophobicContact CG-CD2 3.53Å; F195-Y219 HydrophobicContact CG-CE2 4.28Å; F195-Y219 HydrophobicContact CG-CG 4.48Å; F195-Y222 AromaticContact CD2-CD1 3.64Å; F195-Y222 HydrophobicContact CD2-CD1 3.64Å; F195-Y222 HydrophobicContact CD2-CE1 4.18Å; F195-Y222 HydrophobicContact CD2-CG 4.28Å; F195-Y222 AromaticContact CE2-CD1 3.8Å; F195-Y222 HydrophobicContact CE2-CD1 3.8Å; F195-Y222 AromaticContact CE2-CG 3.97Å; F195-Y222 HydrophobicContact CE2-CG 3.97Å
196	A	95.1	Very high	94.7	Very high	1 Å²	1	65 Å²	65	1%	0.008	33%	0.33	C	S	.	.			trans	-67.3	126.9	173.5	0	0	0	0	0	108.5	K130 R133 T192	K130-A196 WeakPolarHBondContact CE-O 3.47Å; K130-A196 HydrophobicContact CG-CB 4.18Å; K130-A196 VanDerWaalsContact CG-O 3.27Å; K130-A196 WeakPolarHBondContact CG-O 3.49Å; R133-A196 HydrophobicContact CB-CB 3.9Å; R133-A196 HydrophobicContact CG-CB 3.82Å; T192-A196 HydrophobicContact CG2-CB 4.01Å; T192-A196 WeakPolarHBondContact O-CB 3.34Å; T192-A196 PolarHBondContact O-N 2.91Å
197	A	95.8	Very high	94.6	Very high	17 Å²	17	61.3 Å²	61.3	14%	0.14	31%	0.311	C	S	.	.			trans	-151.5	156.6	-178.1	0	0	0	0	0	110	F195 Y208 T212	F195-A197 PolarHBondContact O-N 2.88Å; A197-Y208 WeakPolarHBondContact O-CD2 3.18Å; A197-Y208 PolarHBondContact O-N 3.47Å; A197-Y208 VanDerWaalsContact O-N 3.09Å; A197-T212 HydrophobicContact CB-CG2 4Å
198	T	96.6	Very high	94.4	Very high	35 Å²	35	56.1 Å²	56.1	22%	0.215	29%	0.287	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.1	156.2	164.4	46	0	0	0	0	110.4	E126 C129 T205 V206	E126-T198 HydrophobicContact CB-CG2 4.37Å; C129-T198 HydrophobicContact CB-CG2 3.92Å; T198-T205 HydrophobicContact CG2-CG2 4.32Å; T198-V206 CarbonylContact C-O 3.58Å; T198-V206 WeakPolarHBondContact CA-O 3.29Å
199	G	93.9	Very high	93.9	Very high	19 Å²	19	56.2 Å²	56.2	20%	0.196	29%	0.288	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-158.5	178.6	167	0	0	0	0	0	111.4	T205 V206	G199-T205 CarbonylContact O-C 3.53Å; G199-T205 WeakPolarHBondContact O-CA 3.39Å; G199-V206 PolarHBondContact N-O 3.39Å; G199-V206 WeakPolarHBondContact O-CG2 3.36Å; G199-V206 PolarHBondContact O-N 3.26Å
200	I	92.8	Very high	93.6	Very high	116 Å²	116	56.7 Å²	56.7	60%	0.595	29%	0.29	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-101.7	124.5	-179.2	-56.1	-61.7	0	0	0	109.4	R204	I200-R204 WeakPolarHBondContact CA-O 3.17Å
201	Q	88.2	Confident	93.5	Very high	92 Å²	92	54.7 Å²	54.7	43%	0.43	27%	0.274	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.2	124.7	172.8	-171.6	171.6	13.3	0	0	108.9	N203 R204 V206	Q201-N203 VanDerWaalsContact C-N 3.3Å; Q201-N203 PolarHBondContact O-N 2.9Å; Q201-R204 PolarHBondContact N-O 3.22Å; Q201-R204 PolarHBondContact O-N 2.84Å; Q201-V206 HydrophobicContact CB-CG1 3.97Å; Q201-V206 HydrophobicContact CB-CG2 3.98Å
202	R	86.6	Confident	93.3	Very high	193 Å²	193	54 Å²	54	73%	0.728	27%	0.268	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.5	48.1	-178.9	-60.1	176.9	177.6	169.8	-1.6	112.8	R204	R202-R204 PolarHBondContact O-N 3.43Å
203	N	89.8	Confident	92.9	Very high	159 Å²	159	57.8 Å²	57.8	85%	0.85	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.5	26	-177.8	-154.7	32.6	0	0	0	114.9	Q201	Q201-N203 VanDerWaalsContact C-N 3.3Å; Q201-N203 PolarHBondContact O-N 2.9Å
204	R	91.7	Very high	92.6	Very high	126 Å²	126	63.8 Å²	63.8	48%	0.475	32%	0.319	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-130	142.2	176.2	-65	-176.8	-179.2	-176.5	-1.1	110.7	Y121 I200 Q201 R202 V206	Y121-R204 HydrophobicContact CD2-CB 4.41Å; I200-R204 WeakPolarHBondContact CA-O 3.17Å; Q201-R204 PolarHBondContact N-O 3.22Å; Q201-R204 PolarHBondContact O-N 2.84Å; R202-R204 PolarHBondContact O-N 3.43Å; R204-V206 PolarHBondContact O-N 2.87Å
205	T	96	Very high	92.5	Very high	48 Å²	48	65.4 Å²	65.4	29%	0.294	32%	0.316	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.7	124.2	170.7	-51.4	0	0	0	0	109.3	Y121 W122 T198 G199	Y121-T205 CarbonylContact C-O 3.58Å; Y121-T205 WeakPolarHBondContact CA-O 3.26Å; W122-T205 PolarHBondContact N-O 3.4Å; W122-T205 WeakPolarHBondContact O-CG2 3.47Å; T198-T205 HydrophobicContact CG2-CG2 4.32Å; G199-T205 CarbonylContact O-C 3.53Å; G199-T205 WeakPolarHBondContact O-CA 3.39Å
206	V	95.6	Very high	92.3	Very high	11 Å²	11	65 Å²	65	7%	0.067	32%	0.316	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.2	152.7	175.9	-58.8	0	0	0	0	109.9	D120 T198 G199 Q201 R204 Y208	D120-V206 HydrophobicContact CB-CG1 4.2Å; T198-V206 CarbonylContact C-O 3.58Å; T198-V206 WeakPolarHBondContact CA-O 3.29Å; G199-V206 PolarHBondContact N-O 3.39Å; G199-V206 WeakPolarHBondContact O-CG2 3.36Å; G199-V206 PolarHBondContact O-N 3.26Å; Q201-V206 HydrophobicContact CB-CG1 3.97Å; Q201-V206 HydrophobicContact CB-CG2 3.98Å; R204-V206 PolarHBondContact O-N 2.87Å; V206-Y208 HydrophobicContact CG2-CD2 4.47Å; V206-Y208 HydrophobicContact CG2-CE1 4.4Å; V206-Y208 HydrophobicContact CG2-CE2 3.99Å
207	C	96.3	Very high	92.2	Very high	7 Å²	7	69.4 Å²	69.4	5%	0.047	34%	0.343	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-106.1	113.3	171.7	170.2	0	0	0	0	109	W122 C129 R133	W122-C207 HydrophobicContact CB-CB 3.95Å; W122-C207 HydrophobicContact CD2-CB 3.53Å; W122-C207 HydrophobicContact CE3-CB 3.77Å; W122-C207 HydrophobicContact CG-CB 3.59Å; C129-C207 VanDerWaalsContact CA-SG 3.5Å; C129-C207 HydrophobicContact CB-CB 3.8Å; C129-C207 WeakPolarHBondContact CB-SG 3.38Å; C129-C207 VanDerWaalsContact SG-CA 3.56Å; C129-C207 WeakPolarHBondContact SG-CB 3.33Å; C129-C207 CovalentContact SG-SG 2.03Å; C129-C207 PolarHBondContact SG-SG 3.47Å; R133-C207 PolarHBondContact NE-SG 3.39Å; R133-C207 PolarHBondContact NH2-O 2.95Å
208	Y	93.1	Very high	92.2	Very high	48 Å²	48	73.1 Å²	73.1	19%	0.188	36%	0.36	C	S	.	.			trans	-69.8	141	-177.4	-71.4	-80.7	0	0	0	112.1	R133 A197 V206 T212 P213	R133-Y208 PolarHBondContact NE-O 3.21Å; A197-Y208 WeakPolarHBondContact O-CD2 3.18Å; A197-Y208 PolarHBondContact O-N 3.47Å; A197-Y208 VanDerWaalsContact O-N 3.09Å; V206-Y208 HydrophobicContact CG2-CD2 4.47Å; V206-Y208 HydrophobicContact CG2-CE1 4.4Å; V206-Y208 HydrophobicContact CG2-CE2 3.99Å; Y208-T212 HydrophobicContact CD2-CG2 3.7Å; Y208-T212 HydrophobicContact CE2-CG2 3.87Å; Y208-T212 HydrophobicContact CG-CG2 4.47Å; Y208-P213 HydrophobicContact CE1-CG 4.09Å
209	D	87.2	Confident	92.1	Very high	25 Å²	25	71.6 Å²	71.6	13%	0.134	35%	0.351	C	S	.	.	S	Bend	trans	-70.3	-37.5	-177.6	-65.4	-21.5	0	0	0	113.6	Y116 R133 R319	Y116-D209 PolarHBondContact OH-OD1 3.26Å; R133-D209 IonicContact CZ-OD1 3.99Å; R133-D209 IonicContact NH1-OD1 3.2Å; R133-D209 PolarHBondContact NH1-OD1 3.28Å; R133-D209 IonicContact NH2-OD1 2.93Å; R133-D209 PolarHBondContact NH2-OD1 3.49Å; D209-R319 IonicContact OD1-CZ 2.65Å; D209-R319 IonicContact OD1-NH1 2.88Å; D209-R319 PolarHBondContact OD1-NH1 2.91Å; D209-R319 IonicContact OD2-NH1 2.73Å; D209-R319 PolarHBondContact OD2-NH1 2.87Å
210	L	92.4	Very high	92.2	Very high	10 Å²	10	74.3 Å²	74.3	5%	0.052	36%	0.355	C	S	.	.	S	Bend	trans	-119.9	-67.8	-173.8	-65.2	165.2	0	0	0	110.7	Y137 Y219 K291 Y294 L295 Y315	Y137-L210 WeakPolarHBondContact OH-CD2 3.42Å; L210-Y219 HydrophobicContact CB-CD1 4.37Å; L210-Y219 HydrophobicContact CB-CE1 3.98Å; L210-Y219 HydrophobicContact CB-CE2 4.5Å; L210-Y219 HydrophobicContact CD2-CE1 3.78Å; L210-Y219 WeakPolarHBondContact CD2-OH 3.47Å; L210-Y219 HydrophobicContact CG-CE1 4.38Å; L210-Y219 WeakPolarHBondContact O-CE2 3.2Å; L210-K291 HydrophobicContact CD2-CD 4.36Å; L210-K291 HydrophobicContact CD2-CG 4.41Å; L210-Y294 HydrophobicContact CD1-CD1 3.87Å; L210-Y294 HydrophobicContact CD1-CE1 3.79Å; L210-L295 HydrophobicContact CD1-CD2 3.85Å; L210-Y315 HydrophobicContact CD1-CE1 4.29Å
211	S	93.9	Very high	92.4	Very high	5 Å²	5	72.6 Å²	72.6	4%	0.035	35%	0.352	C	S	.	.			trans	-155.4	163.9	176.6	64.2	0	0	0	0	109.7	F195 R215 Y219 R298	F195-S211 WeakPolarHBondContact O-CA 3.34Å; S211-R215 PolarHBondContact OG-O 2.9Å; S211-R215 VanDerWaalsContact OG-O 3.05Å; S211-Y219 WeakPolarHBondContact OG-CB 3.28Å; S211-R298 PolarHBondContact OG-NH2 3.21Å
212	T	92	Very high	92.8	Very high	27 Å²	27	69.5 Å²	69.5	17%	0.166	34%	0.337	C	S	.	.			trans	-61	154.7	169.3	61.5	0	0	0	0	110.5	A197 Y208 K214 R215 S216	A197-T212 HydrophobicContact CB-CG2 4Å; Y208-T212 HydrophobicContact CD2-CG2 3.7Å; Y208-T212 HydrophobicContact CE2-CG2 3.87Å; Y208-T212 HydrophobicContact CG-CG2 4.47Å; T212-K214 PolarHBondContact O-N 3.29Å; T212-K214 VanDerWaalsContact O-N 3.15Å; T212-R215 CarbonylContact O-C 3.55Å; T212-R215 PolarHBondContact O-N 3.07Å; T212-S216 PolarHBondContact O-N 3.44Å
213	P	87.9	Confident	93.3	Very high	86 Å²	86	60.3 Å²	60.3	56%	0.558	30%	0.302	S	S	*	.	G	3₁₀ helix	trans	-55.2	-33.8	177.7	-27.8	35.4	0	0	0	113.4	Y208 R215 S216	Y208-P213 HydrophobicContact CE1-CG 4.09Å; P213-R215 VanDerWaalsContact C-N 3.33Å; P213-R215 PolarHBondContact O-N 3.47Å; P213-S216 PolarHBondContact O-N 3.15Å; P213-S216 PolarHBondContact O-OG 3.49Å; P213-S216 VanDerWaalsContact O-OG 3.1Å
214	K	88.9	Confident	93.7	Very high	199 Å²	199	55.5 Å²	55.5	87%	0.865	28%	0.275	S	S	*	.	G	3₁₀ helix	trans	-67.4	-30.1	178.4	-64.6	-176.2	178.2	-176.4	0	113.3	T212	T212-K214 PolarHBondContact O-N 3.29Å; T212-K214 VanDerWaalsContact O-N 3.15Å
215	R	92.8	Very high	93.9	Very high	121 Å²	121	51.6 Å²	51.6	46%	0.457	27%	0.269	S	S	.	.	G	3₁₀ helix	trans	-104.9	25.1	-179.3	-64.9	-172.6	175.9	-177.5	-2.5	112.2	T194 S211 T212 P213 Y219	T194-R215 PolarHBondContact O-NH1 3.29Å; S211-R215 PolarHBondContact OG-O 2.9Å; S211-R215 VanDerWaalsContact OG-O 3.05Å; T212-R215 CarbonylContact O-C 3.55Å; T212-R215 PolarHBondContact O-N 3.07Å; P213-R215 VanDerWaalsContact C-N 3.33Å; P213-R215 PolarHBondContact O-N 3.47Å; R215-Y219 VanDerWaalsContact O-CB 3.23Å; R215-Y219 WeakPolarHBondContact O-CB 3.13Å; R215-Y219 PolarHBondContact O-N 3.05Å; R215-Y219 VanDerWaalsContact O-N 3.1Å
216	S	91.3	Very high	93.9	Very high	19 Å²	19	49.4 Å²	49.4	13%	0.133	26%	0.256	C	S	.	.	H	α-helix	trans	-69.8	-38.8	-179.1	58.6	0	0	0	0	112.6	T212 P213 Y220 R298	T212-S216 PolarHBondContact O-N 3.44Å; P213-S216 PolarHBondContact O-N 3.15Å; P213-S216 PolarHBondContact O-OG 3.49Å; P213-S216 VanDerWaalsContact O-OG 3.1Å; S216-Y220 PolarHBondContact O-N 2.89Å; S216-R298 VanDerWaalsContact CB-NH2 3.27Å
217	V	93.4	Very high	94	Very high	94 Å²	94	49.6 Å²	49.6	57%	0.57	26%	0.257	S	S	*	.	H	α-helix	trans	-70.2	-46.5	178.6	-179.4	0	0	0	0	110.1	Y219 Y220 P221 T299	V217-Y219 VanDerWaalsContact C-N 3.27Å; V217-Y219 PolarHBondContact O-N 3.19Å; V217-Y220 VanDerWaalsContact O-CB 3.29Å; V217-Y220 WeakPolarHBondContact O-CB 3.17Å; V217-Y220 PolarHBondContact O-N 3.47Å; V217-Y220 VanDerWaalsContact O-N 3.12Å; V217-P221 VanDerWaalsContact O-CD 3.31Å; V217-P221 WeakPolarHBondContact O-CD 3.3Å; V217-T299 HydrophobicContact CG2-CG2 4.48Å
218	D	94.9	Very high	94	Very high	96 Å²	96	54.7 Å²	54.7	51%	0.513	28%	0.279	S	S	.	.	H	α-helix	trans	-62.3	-33.9	177	-52.1	-27.4	0	0	0	112.8	F195 P221	F195-D218 HydrophobicContact CE1-CB 4.01Å; F195-D218 WeakPolarHBondContact CZ-O 3.39Å; D218-P221 WeakPolarHBondContact O-CD 3.18Å; D218-P221 WeakPolarHBondContact O-CG 3.36Å
219	Y	96	Very high	94.1	Very high	2 Å²	2	56.2 Å²	56.2	1%	0.008	29%	0.29	C	S	.	.	H	α-helix	trans	-71.7	-29.1	177.2	179.9	-90.5	0	0	0	112.8	F195 L210 S211 R215 V217 Y222 G223 L295	F195-Y219 HydrophobicContact CB-CD2 3.58Å; F195-Y219 HydrophobicContact CB-CE2 4.03Å; F195-Y219 AromaticContact CD1-CD2 3.89Å; F195-Y219 HydrophobicContact CD1-CD2 3.89Å; F195-Y219 HydrophobicContact CD1-CG 4.44Å; F195-Y219 AromaticContact CD2-CD2 3.85Å; F195-Y219 HydrophobicContact CD2-CD2 3.85Å; F195-Y219 HydrophobicContact CD2-CE2 4.39Å; F195-Y219 HydrophobicContact CE2-CD2 4.48Å; F195-Y219 AromaticContact CG-CD2 3.53Å; F195-Y219 HydrophobicContact CG-CD2 3.53Å; F195-Y219 HydrophobicContact CG-CE2 4.28Å; F195-Y219 HydrophobicContact CG-CG 4.48Å; L210-Y219 HydrophobicContact CB-CD1 4.37Å; L210-Y219 HydrophobicContact CB-CE1 3.98Å; L210-Y219 HydrophobicContact CB-CE2 4.5Å; L210-Y219 HydrophobicContact CD2-CE1 3.78Å; L210-Y219 WeakPolarHBondContact CD2-OH 3.47Å; L210-Y219 HydrophobicContact CG-CE1 4.38Å; L210-Y219 WeakPolarHBondContact O-CE2 3.2Å; S211-Y219 WeakPolarHBondContact OG-CB 3.28Å; R215-Y219 VanDerWaalsContact O-CB 3.23Å; R215-Y219 WeakPolarHBondContact O-CB 3.13Å; R215-Y219 PolarHBondContact O-N 3.05Å; R215-Y219 VanDerWaalsContact O-N 3.1Å; V217-Y219 VanDerWaalsContact C-N 3.27Å; V217-Y219 PolarHBondContact O-N 3.19Å; Y219-Y222 AromaticContact CD2-CD1 3.86Å; Y219-Y222 HydrophobicContact CD2-CD1 3.86Å; Y219-Y222 AromaticContact CE2-CD1 3.51Å; Y219-Y222 HydrophobicContact CE2-CD1 3.51Å; Y219-Y222 AromaticContact CE2-CE1 3.79Å; Y219-Y222 HydrophobicContact CE2-CE1 3.79Å; Y219-Y222 WeakPolarHBondContact O-CB 3.15Å; Y219-Y222 PolarHBondContact O-N 2.86Å; Y219-G223 PolarHBondContact O-N 3.48Å; Y219-L295 HydrophobicContact CD1-CD2 3.81Å; Y219-L295 HydrophobicContact CE1-CD1 4.09Å; Y219-L295 HydrophobicContact CE1-CD2 3.73Å
220	Y	96.1	Very high	94.4	Very high	76 Å²	76	55 Å²	55	30%	0.298	28%	0.283	S	S	.	.	H	α-helix	trans	-52.2	-54	-173.7	177.8	-96.8	0	0	0	114.3	S216 V217 Y222 G223 M224 L295 V296 T299	S216-Y220 PolarHBondContact O-N 2.89Å; V217-Y220 VanDerWaalsContact O-CB 3.29Å; V217-Y220 WeakPolarHBondContact O-CB 3.17Å; V217-Y220 PolarHBondContact O-N 3.47Å; V217-Y220 VanDerWaalsContact O-N 3.12Å; Y220-Y222 VanDerWaalsContact C-N 3.3Å; Y220-Y222 PolarHBondContact O-N 3.31Å; Y220-G223 PolarHBondContact O-N 2.99Å; Y220-G223 VanDerWaalsContact O-N 3.14Å; Y220-M224 HydrophobicContact CD1-CG 4.27Å; Y220-M224 HydrophobicContact CD2-CG 4.23Å; Y220-M224 HydrophobicContact CE1-CG 3.91Å; Y220-M224 HydrophobicContact CE2-CG 3.84Å; Y220-M224 HydrophobicContact CE2-SD 4Å; Y220-M224 HydrophobicContact CG-CG 4.42Å; Y220-M224 WeakPolarHBondContact O-CG 3.28Å; Y220-M224 PolarHBondContact O-N 3.07Å; Y220-L295 HydrophobicContact CD2-CB 4.14Å; Y220-L295 WeakPolarHBondContact CD2-O 3.29Å; Y220-L295 HydrophobicContact CE2-CB 4.39Å; Y220-V296 HydrophobicContact CE2-CG2 4.03Å; Y220-T299 HydrophobicContact CD2-CG2 3.94Å; Y220-T299 HydrophobicContact CG-CG2 4.09Å
221	P	96.9	Very high	94.6	Very high	80 Å²	80	55 Å²	55	52%	0.519	28%	0.283	S	S	.	.	H	α-helix	trans	-59.9	-41.2	180	23.2	-34.3	0	0	0	112.2	V217 D218 M224 A225	V217-P221 VanDerWaalsContact O-CD 3.31Å; V217-P221 WeakPolarHBondContact O-CD 3.3Å; D218-P221 WeakPolarHBondContact O-CD 3.18Å; D218-P221 WeakPolarHBondContact O-CG 3.36Å; P221-M224 PolarHBondContact O-N 3.37Å; P221-A225 WeakPolarHBondContact O-CB 3.48Å; P221-A225 PolarHBondContact O-N 3.47Å
222	Y	96.9	Very high	94.6	Very high	28 Å²	28	58 Å²	58	11%	0.11	30%	0.298	C	S	.	.	H	α-helix	trans	-61.4	-47.9	174.6	169.8	-120.5	0	0	0	111.7	L188 P191 T192 F195 Y219 Y220 M224 A225 L226	L188-Y222 VanDerWaalsContact O-CE2 3.24Å; L188-Y222 WeakPolarHBondContact O-CE2 3.49Å; L188-Y222 PolarHBondContact O-OH 3.24Å; P191-Y222 HydrophobicContact CB-CD1 4.24Å; P191-Y222 HydrophobicContact CB-CD2 3.84Å; P191-Y222 HydrophobicContact CB-CE1 4.02Å; P191-Y222 HydrophobicContact CB-CE2 3.61Å; P191-Y222 HydrophobicContact CB-CG 4.15Å; P191-Y222 HydrophobicContact CG-CD2 3.91Å; P191-Y222 HydrophobicContact CG-CE2 3.55Å; T192-Y222 PolarHBondContact OG1-OH 3.36Å; F195-Y222 AromaticContact CD2-CD1 3.64Å; F195-Y222 HydrophobicContact CD2-CD1 3.64Å; F195-Y222 HydrophobicContact CD2-CE1 4.18Å; F195-Y222 HydrophobicContact CD2-CG 4.28Å; F195-Y222 AromaticContact CE2-CD1 3.8Å; F195-Y222 HydrophobicContact CE2-CD1 3.8Å; F195-Y222 AromaticContact CE2-CG 3.97Å; F195-Y222 HydrophobicContact CE2-CG 3.97Å; Y219-Y222 AromaticContact CD2-CD1 3.86Å; Y219-Y222 HydrophobicContact CD2-CD1 3.86Å; Y219-Y222 AromaticContact CE2-CD1 3.51Å; Y219-Y222 HydrophobicContact CE2-CD1 3.51Å; Y219-Y222 AromaticContact CE2-CE1 3.79Å; Y219-Y222 HydrophobicContact CE2-CE1 3.79Å; Y219-Y222 WeakPolarHBondContact O-CB 3.15Å; Y219-Y222 PolarHBondContact O-N 2.86Å; Y220-Y222 VanDerWaalsContact C-N 3.3Å; Y220-Y222 PolarHBondContact O-N 3.31Å; Y222-M224 VanDerWaalsContact C-N 3.29Å; Y222-M224 PolarHBondContact O-N 3.14Å; Y222-A225 PolarHBondContact O-N 2.86Å; Y222-L226 HydrophobicContact CE1-CD2 4.4Å; Y222-L226 HydrophobicContact CE2-CB 4.38Å; Y222-L226 VanDerWaalsContact O-CB 3.25Å; Y222-L226 WeakPolarHBondContact O-CB 3.48Å; Y222-L226 PolarHBondContact O-N 3Å
223	G	96.5	Very high	94.7	Very high	0 Å²	0	61.4 Å²	61.4	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-61.2	-36.5	179.6	0	0	0	0	0	113.2	Y219 Y220 T227 K291	Y219-G223 PolarHBondContact O-N 3.48Å; Y220-G223 PolarHBondContact O-N 2.99Å; Y220-G223 VanDerWaalsContact O-N 3.14Å; G223-T227 PolarHBondContact O-N 3.29Å; G223-T227 PolarHBondContact O-OG1 3.44Å; G223-K291 PolarHBondContact O-NZ 3.24Å
224	M	97.4	Very high	94.9	Very high	58 Å²	58	57.5 Å²	57.5	29%	0.286	29%	0.289	S	S	.	.	H	α-helix	trans	-71	-48.6	174.9	-67.3	-54.7	-68.6	0	0	111.8	Y220 P221 Y222 L226 T227 F228 T292	Y220-M224 HydrophobicContact CD1-CG 4.27Å; Y220-M224 HydrophobicContact CD2-CG 4.23Å; Y220-M224 HydrophobicContact CE1-CG 3.91Å; Y220-M224 HydrophobicContact CE2-CG 3.84Å; Y220-M224 HydrophobicContact CE2-SD 4Å; Y220-M224 HydrophobicContact CG-CG 4.42Å; Y220-M224 WeakPolarHBondContact O-CG 3.28Å; Y220-M224 PolarHBondContact O-N 3.07Å; P221-M224 PolarHBondContact O-N 3.37Å; Y222-M224 VanDerWaalsContact C-N 3.29Å; Y222-M224 PolarHBondContact O-N 3.14Å; M224-L226 VanDerWaalsContact C-N 3.27Å; M224-L226 PolarHBondContact O-N 3.16Å; M224-T227 PolarHBondContact O-N 3.35Å; M224-T227 VanDerWaalsContact O-N 3.12Å; M224-F228 PolarHBondContact O-N 3.44Å; M224-T292 HydrophobicContact CE-CG2 3.81Å; M224-T292 HydrophobicContact SD-CG2 3.85Å
225	A	97	Very high	95	Very high	43 Å²	43	50.2 Å²	50.2	36%	0.355	26%	0.258	S	S	.	.	H	α-helix	trans	-57.7	-42.2	176.2	0	0	0	0	0	111.4	P221 Y222 T227 F228 L229	P221-A225 WeakPolarHBondContact O-CB 3.48Å; P221-A225 PolarHBondContact O-N 3.47Å; Y222-A225 PolarHBondContact O-N 2.86Å; A225-T227 PolarHBondContact O-N 2.81Å; A225-F228 PolarHBondContact O-N 2.92Å; A225-L229 WeakPolarHBondContact O-CB 3.27Å; A225-L229 WeakPolarHBondContact O-CG 3.3Å; A225-L229 PolarHBondContact O-N 3.25Å
226	L	96.3	Very high	94.9	Very high	2 Å²	2	48.7 Å²	48.7	1%	0.01	26%	0.258	C	S	.	.	H	α-helix	trans	-63.9	-38.5	177.2	-172.3	64	0	0	0	112.3	Y137 H141 L188 Y222 M224 G230	Y137-L226 HydrophobicContact CD1-CD2 3.83Å; Y137-L226 HydrophobicContact CE1-CD2 4.14Å; Y137-L226 HydrophobicContact CG-CD2 4.3Å; H141-L226 PolarHBondContact CE1-O 3.37Å; H141-L226 WeakPolarHBondContact NE2-CD1 3.41Å; H141-L226 VanDerWaalsContact NE2-CG 3.26Å; H141-L226 WeakPolarHBondContact NE2-CG 3.43Å; L188-L226 HydrophobicContact CB-CD1 3.93Å; Y222-L226 HydrophobicContact CE1-CD2 4.4Å; Y222-L226 HydrophobicContact CE2-CB 4.38Å; Y222-L226 VanDerWaalsContact O-CB 3.25Å; Y222-L226 WeakPolarHBondContact O-CB 3.48Å; Y222-L226 PolarHBondContact O-N 3Å; M224-L226 VanDerWaalsContact C-N 3.27Å; M224-L226 PolarHBondContact O-N 3.16Å; L226-G230 VanDerWaalsContact O-CA 3.23Å; L226-G230 WeakPolarHBondContact O-CA 3.37Å; L226-G230 PolarHBondContact O-N 3.01Å
227	T	96.3	Very high	94.7	Very high	15 Å²	15	49.1 Å²	49.1	9%	0.092	27%	0.266	C	S	.	.	H	α-helix	trans	-66.8	-45	172.7	-64.2	0	0	0	0	111.4	G223 M224 A225 F231 L232 H288 K291 T292	G223-T227 PolarHBondContact O-N 3.29Å; G223-T227 PolarHBondContact O-OG1 3.44Å; M224-T227 PolarHBondContact O-N 3.35Å; M224-T227 VanDerWaalsContact O-N 3.12Å; A225-T227 PolarHBondContact O-N 2.81Å; T227-F231 WeakPolarHBondContact O-CA 3.41Å; T227-F231 WeakPolarHBondContact O-CB 3.31Å; T227-F231 PolarHBondContact O-N 3.42Å; T227-L232 PolarHBondContact O-N 2.87Å; T227-L232 VanDerWaalsContact O-N 3.07Å; T227-H288 HydrophobicContact CG2-CB 4.38Å; T227-K291 WeakPolarHBondContact OG1-CE 3.41Å; T227-K291 PolarHBondContact OG1-NZ 3.22Å; T227-T292 PolarHBondContact OG1-OG1 2.82Å
228	F	96.3	Very high	94.4	Very high	114 Å²	114	44.6 Å²	44.6	50%	0.5	24%	0.238	S	C	.	.	I	π-helix	trans	-67.2	-55.5	-175.9	-177.2	-96.3	0	0	0	111.9	M224 A225 L232 L233	M224-F228 PolarHBondContact O-N 3.44Å; A225-F228 PolarHBondContact O-N 2.92Å; F228-L232 HydrophobicContact CD2-CB 4.45Å; F228-L232 HydrophobicContact CD2-CD2 3.76Å; F228-L232 HydrophobicContact CE2-CD2 3.9Å; F228-L232 PolarHBondContact O-N 3.17Å; F228-L233 PolarHBondContact O-N 3.42Å
229	L	96.2	Very high	94.1	Very high	80 Å²	80	42.6 Å²	42.6	42%	0.419	23%	0.227	S	C	.	.	I	π-helix	trans	-72.7	-39.6	-177.5	-62.2	174.5	0	0	0	112	L188 A225 P234	L188-L229 HydrophobicContact CD2-CB 4.05Å; L188-L229 HydrophobicContact CD2-CD1 3.88Å; A225-L229 WeakPolarHBondContact O-CB 3.27Å; A225-L229 WeakPolarHBondContact O-CG 3.3Å; A225-L229 PolarHBondContact O-N 3.25Å; L229-P234 VanDerWaalsContact O-CD 3.29Å; L229-P234 WeakPolarHBondContact O-CD 3.35Å
230	G	93.9	Very high	93.7	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	25%	0.252	C	S	.	.	I	π-helix	trans	-88.7	-12.4	-172.9	0	0	0	0	0	115.1	H141 L226	H141-G230 VanDerWaalsContact ND1-C 3.31Å; H141-G230 VanDerWaalsContact ND1-CA 3.33Å; H141-G230 WeakPolarHBondContact ND1-CA 3.28Å; H141-G230 PolarHBondContact ND1-O 3.15Å; L226-G230 VanDerWaalsContact O-CA 3.23Å; L226-G230 WeakPolarHBondContact O-CA 3.37Å; L226-G230 PolarHBondContact O-N 3.01Å
231	F	95.3	Very high	93.1	Very high	11 Å²	11	44.8 Å²	44.8	5%	0.048	24%	0.244	C	C	.	.	I	π-helix	trans	-134.8	-57	179.5	168.7	-103.6	0	0	0	113.4	I144 T227 L233 P234 F235 F280 F284 L285 H288	I144-F231 HydrophobicContact CD1-CB 4.28Å; I144-F231 HydrophobicContact CD1-CD2 3.95Å; T227-F231 WeakPolarHBondContact O-CA 3.41Å; T227-F231 WeakPolarHBondContact O-CB 3.31Å; T227-F231 PolarHBondContact O-N 3.42Å; F231-L233 PolarHBondContact O-N 2.89Å; F231-P234 WeakPolarHBondContact O-CD 3.2Å; F231-F235 HydrophobicContact CE2-CB 4.49Å; F231-F235 WeakPolarHBondContact O-CB 3.46Å; F231-F235 PolarHBondContact O-N 3.27Å; F231-F280 HydrophobicContact CE2-CD1 4.02Å; F231-F280 HydrophobicContact CE2-CE1 4.35Å; F231-F284 HydrophobicContact CD2-CB 4.15Å; F231-F284 HydrophobicContact CE2-CB 3.81Å; F231-L285 HydrophobicContact CE1-CD1 4.13Å; F231-L285 HydrophobicContact CZ-CB 4.12Å; F231-L285 HydrophobicContact CZ-CD1 3.78Å; F231-H288 HydrophobicContact CD1-CB 3.64Å; F231-H288 AromaticContact CD1-CD2 3.94Å; F231-H288 AromaticContact CD1-CG 3.7Å; F231-H288 HydrophobicContact CD2-CB 4.42Å; F231-H288 AromaticContact CD2-CD2 3.24Å; F231-H288 WeakPolarHBondContact CD2-CD2 3.21Å; F231-H288 AromaticContact CD2-CG 3.89Å; F231-H288 AromaticContact CD2-NE2 3.81Å; F231-H288 HydrophobicContact CE1-CB 3.85Å; F231-H288 AromaticContact CE2-CD2 3.84Å; F231-H288 HydrophobicContact CG-CB 3.95Å; F231-H288 AromaticContact CG-CD2 3.29Å; F231-H288 WeakPolarHBondContact CG-CD2 3.27Å; F231-H288 AromaticContact CG-CG 3.47Å; F231-H288 VanDerWaalsContact CG-CG 3.47Å; F231-H288 AromaticContact CG-NE2 3.8Å; F231-H288 HydrophobicContact CZ-CB 4.33Å
232	L	94.6	Very high	92.4	Very high	66 Å²	66	41.4 Å²	41.4	35%	0.346	22%	0.221	S	C	.	.	I	π-helix	trans	-64.3	-47.3	-171	-174.1	61.9	0	0	0	112.1	T227 F228 F235 L236	T227-L232 PolarHBondContact O-N 2.87Å; T227-L232 VanDerWaalsContact O-N 3.07Å; F228-L232 HydrophobicContact CD2-CB 4.45Å; F228-L232 HydrophobicContact CD2-CD2 3.76Å; F228-L232 HydrophobicContact CE2-CD2 3.9Å; F228-L232 PolarHBondContact O-N 3.17Å; L232-F235 PolarHBondContact O-N 3.44Å; L232-L236 HydrophobicContact CD1-CD1 4.34Å; L232-L236 HydrophobicContact CD1-CG 4.3Å; L232-L236 HydrophobicContact CG-CD1 4.08Å; L232-L236 HydrophobicContact CG-CG 4.47Å; L232-L236 WeakPolarHBondContact O-CB 3.28Å; L232-L236 VanDerWaalsContact O-CG 3.26Å; L232-L236 WeakPolarHBondContact O-CG 3.25Å; L232-L236 PolarHBondContact O-N 3.46Å
233	L	93.4	Very high	91.8	Very high	100 Å²	100	44.1 Å²	44.1	52%	0.524	24%	0.243	S	C	.	.	H	α-helix	trans	-62.4	-50.4	179.4	-177.5	161.6	0	0	0	112.3	F228 F231 F235 L236 G237	F228-L233 PolarHBondContact O-N 3.42Å; F231-L233 PolarHBondContact O-N 2.89Å; L233-F235 VanDerWaalsContact C-N 3.35Å; L233-F235 PolarHBondContact O-N 3.48Å; L233-L236 PolarHBondContact O-N 2.89Å; L233-G237 PolarHBondContact O-N 3.27Å; L233-G237 VanDerWaalsContact O-N 3.07Å
234	P	92.3	Very high	91.2	Very high	4 Å²	4	51.5 Å²	51.5	3%	0.026	27%	0.271	C	S	.	.	H	α-helix	trans	-58.3	-42.9	173.2	-26.4	33.5	0	0	0	113.5	I144 L145 L229 F231 L236 G237 V238	I144-P234 HydrophobicContact CG2-CB 3.47Å; I144-P234 VanDerWaalsContact CG2-CB 3.47Å; I144-P234 HydrophobicContact CG2-CG 3.95Å; L145-P234 HydrophobicContact CD2-CB 4.25Å; L145-P234 HydrophobicContact CD2-CG 3.71Å; L229-P234 VanDerWaalsContact O-CD 3.29Å; L229-P234 WeakPolarHBondContact O-CD 3.35Å; F231-P234 WeakPolarHBondContact O-CD 3.2Å; P234-L236 PolarHBondContact O-N 2.88Å; P234-G237 PolarHBondContact O-N 2.86Å; P234-V238 WeakPolarHBondContact O-CG2 3.19Å; P234-V238 PolarHBondContact O-N 3.24Å
235	F	90.4	Very high	90.2	Very high	45 Å²	45	48.8 Å²	48.8	20%	0.197	26%	0.257	C	S	.	.	H	α-helix	trans	-60.5	-46.7	179.3	176	-103.8	0	0	0	111.8	F231 L232 L233 G237 V238 M239 F280	F231-F235 HydrophobicContact CE2-CB 4.49Å; F231-F235 WeakPolarHBondContact O-CB 3.46Å; F231-F235 PolarHBondContact O-N 3.27Å; L232-F235 PolarHBondContact O-N 3.44Å; L233-F235 VanDerWaalsContact C-N 3.35Å; L233-F235 PolarHBondContact O-N 3.48Å; F235-G237 VanDerWaalsContact C-N 3.32Å; F235-G237 PolarHBondContact O-N 3.26Å; F235-V238 PolarHBondContact O-N 2.81Å; F235-M239 HydrophobicContact CD1-CG 4.25Å; F235-M239 HydrophobicContact CD2-CE 4.35Å; F235-M239 HydrophobicContact CD2-CG 4.4Å; F235-M239 HydrophobicContact CE1-CG 3.82Å; F235-M239 HydrophobicContact CE2-CE 3.8Å; F235-M239 HydrophobicContact CE2-CG 4.01Å; F235-M239 HydrophobicContact CE2-SD 4.22Å; F235-M239 HydrophobicContact CZ-CE 4.26Å; F235-M239 HydrophobicContact CZ-CG 3.7Å; F235-M239 HydrophobicContact CZ-SD 4.06Å; F235-M239 WeakPolarHBondContact O-CG 3.29Å; F235-M239 PolarHBondContact O-N 3.31Å; F235-F280 HydrophobicContact CB-CD1 4.5Å; F235-F280 HydrophobicContact CB-CE1 4.18Å; F235-F280 HydrophobicContact CD2-CB 4.38Å; F235-F280 AromaticContact CD2-CD1 3.52Å; F235-F280 HydrophobicContact CD2-CD1 3.52Å; F235-F280 AromaticContact CD2-CE1 3.96Å; F235-F280 HydrophobicContact CD2-CE1 3.96Å; F235-F280 HydrophobicContact CD2-CG 4.05Å; F235-F280 HydrophobicContact CE2-CB 4.28Å; F235-F280 HydrophobicContact CE2-CD1 4.24Å; F235-F280 HydrophobicContact CE2-CG 4.42Å; F235-F280 HydrophobicContact CG-CD1 4.46Å
236	L	91	Very high	89.3	Confident	89 Å²	89	48.6 Å²	48.6	47%	0.466	26%	0.256	S	S	.	.	H	α-helix	trans	-60.1	-42.7	175.2	-70.4	172.1	0	0	0	111.4	L232 L233 P234 V238 M239 I240	L232-L236 HydrophobicContact CD1-CD1 4.34Å; L232-L236 HydrophobicContact CD1-CG 4.3Å; L232-L236 HydrophobicContact CG-CD1 4.08Å; L232-L236 HydrophobicContact CG-CG 4.47Å; L232-L236 WeakPolarHBondContact O-CB 3.28Å; L232-L236 VanDerWaalsContact O-CG 3.26Å; L232-L236 WeakPolarHBondContact O-CG 3.25Å; L232-L236 PolarHBondContact O-N 3.46Å; L233-L236 PolarHBondContact O-N 2.89Å; P234-L236 PolarHBondContact O-N 2.88Å; L236-V238 PolarHBondContact O-N 3.22Å; L236-M239 PolarHBondContact O-N 2.79Å; L236-I240 VanDerWaalsContact O-CG1 3.27Å; L236-I240 WeakPolarHBondContact O-CG1 3.5Å; L236-I240 PolarHBondContact O-N 3.46Å
237	G	88.3	Confident	88.5	Confident	28 Å²	28	53.3 Å²	53.3	29%	0.289	28%	0.278	S	S	.	.	H	α-helix	trans	-58.3	-45.5	175	0	0	0	0	0	112.9	L233 P234 F235 C241	L233-G237 PolarHBondContact O-N 3.27Å; L233-G237 VanDerWaalsContact O-N 3.07Å; P234-G237 PolarHBondContact O-N 2.86Å; F235-G237 VanDerWaalsContact C-N 3.32Å; F235-G237 PolarHBondContact O-N 3.26Å; G237-C241 WeakPolarHBondContact O-CB 3.47Å; G237-C241 PolarHBondContact O-N 2.96Å; G237-C241 PolarHBondContact O-SG 2.68Å
238	V	87.4	Confident	87.5	Confident	0 Å²	0	56.4 Å²	56.4	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-63.8	-46.2	175.9	174.2	0	0	0	0	111.3	T148 P234 F235 L236 I240 C241 Y242 V276 F280	T148-V238 HydrophobicContact CG2-CG2 3.94Å; T148-V238 WeakPolarHBondContact OG1-CG2 3.22Å; P234-V238 WeakPolarHBondContact O-CG2 3.19Å; P234-V238 PolarHBondContact O-N 3.24Å; F235-V238 PolarHBondContact O-N 2.81Å; L236-V238 PolarHBondContact O-N 3.22Å; V238-I240 PolarHBondContact O-N 2.94Å; V238-C241 WeakPolarHBondContact O-CB 3.48Å; V238-C241 PolarHBondContact O-N 2.84Å; V238-Y242 HydrophobicContact CG1-CD2 3.66Å; V238-Y242 HydrophobicContact CG1-CE1 4.47Å; V238-Y242 HydrophobicContact CG1-CE2 3.41Å; V238-Y242 VanDerWaalsContact CG1-CE2 3.41Å; V238-Y242 HydrophobicContact CG1-CG 4.31Å; V238-Y242 WeakPolarHBondContact O-CB 3.45Å; V238-Y242 PolarHBondContact O-N 3.48Å; V238-V276 HydrophobicContact CG1-CG1 3.99Å; V238-F280 HydrophobicContact CG2-CE2 4.36Å; V238-F280 HydrophobicContact CG2-CZ 4.36Å
239	M	87.1	Confident	86.3	Confident	54 Å²	54	52.1 Å²	52.1	27%	0.266	28%	0.275	S	S	.	.	H	α-helix	trans	-60	-45.7	178.6	-72.9	-56.3	108.6	0	0	111.4	F235 L236 C241 Y242 C243	F235-M239 HydrophobicContact CD1-CG 4.25Å; F235-M239 HydrophobicContact CD2-CE 4.35Å; F235-M239 HydrophobicContact CD2-CG 4.4Å; F235-M239 HydrophobicContact CE1-CG 3.82Å; F235-M239 HydrophobicContact CE2-CE 3.8Å; F235-M239 HydrophobicContact CE2-CG 4.01Å; F235-M239 HydrophobicContact CE2-SD 4.22Å; F235-M239 HydrophobicContact CZ-CE 4.26Å; F235-M239 HydrophobicContact CZ-CG 3.7Å; F235-M239 HydrophobicContact CZ-SD 4.06Å; F235-M239 WeakPolarHBondContact O-CG 3.29Å; F235-M239 PolarHBondContact O-N 3.31Å; L236-M239 PolarHBondContact O-N 2.79Å; M239-C241 PolarHBondContact O-N 3.46Å; M239-Y242 HydrophobicContact CE-CD2 4.35Å; M239-Y242 PolarHBondContact O-N 2.92Å; M239-C243 WeakPolarHBondContact O-CB 3.3Å; M239-C243 PolarHBondContact O-N 3.29Å; M239-C243 PolarHBondContact O-SG 3.34Å
240	I	87.3	Confident	85.1	Confident	104 Å²	104	53.4 Å²	53.4	53%	0.533	29%	0.289	S	S	.	.	H	α-helix	trans	-59.9	-47.2	176	-67.9	165	0	0	0	110.7	L236 V238 Y242 C243 R244	L236-I240 VanDerWaalsContact O-CG1 3.27Å; L236-I240 WeakPolarHBondContact O-CG1 3.5Å; L236-I240 PolarHBondContact O-N 3.46Å; V238-I240 PolarHBondContact O-N 2.94Å; I240-Y242 VanDerWaalsContact C-N 3.28Å; I240-Y242 PolarHBondContact O-N 3.12Å; I240-C243 PolarHBondContact O-N 2.03Å; I240-R244 HydrophobicContact CG2-CG 4.44Å; I240-R244 WeakPolarHBondContact O-CB 3.43Å; I240-R244 VanDerWaalsContact O-CG 3.24Å; I240-R244 WeakPolarHBondContact O-CG 3.26Å; I240-R244 PolarHBondContact O-N 3.32Å
241	C	83.6	Confident	83.9	Confident	20 Å²	20	61.3 Å²	61.3	14%	0.135	32%	0.319	C	S	.	.	H	α-helix	trans	-58	-42	177.8	-70.2	0	0	0	0	111.8	Y155 G237 V238 M239 M245	Y155-C241 HydrophobicContact CG-CB 4.48Å; G237-C241 WeakPolarHBondContact O-CB 3.47Å; G237-C241 PolarHBondContact O-N 2.96Å; G237-C241 PolarHBondContact O-SG 2.68Å; V238-C241 WeakPolarHBondContact O-CB 3.48Å; V238-C241 PolarHBondContact O-N 2.84Å; M239-C241 PolarHBondContact O-N 3.46Å; C241-M245 VanDerWaalsContact O-CB 3.3Å; C241-M245 WeakPolarHBondContact O-CB 3.41Å; C241-M245 PolarHBondContact O-N 3.42Å
242	Y	83	Confident	82.1	Confident	9 Å²	9	66.1 Å²	66.1	4%	0.035	35%	0.352	C	S	.	.	H	α-helix	trans	-75.8	-37.7	-178.6	-70.6	-10	0	0	0	113.4	S151 V238 M239 I240 R244 M245 A246 M272 I273 V276	S151-Y242 WeakPolarHBondContact CB-OH 3.06Å; S151-Y242 PolarHBondContact OG-OH 2.79Å; V238-Y242 HydrophobicContact CG1-CD2 3.66Å; V238-Y242 HydrophobicContact CG1-CE1 4.47Å; V238-Y242 HydrophobicContact CG1-CE2 3.41Å; V238-Y242 VanDerWaalsContact CG1-CE2 3.41Å; V238-Y242 HydrophobicContact CG1-CG 4.31Å; V238-Y242 WeakPolarHBondContact O-CB 3.45Å; V238-Y242 PolarHBondContact O-N 3.48Å; M239-Y242 HydrophobicContact CE-CD2 4.35Å; M239-Y242 PolarHBondContact O-N 2.92Å; I240-Y242 VanDerWaalsContact C-N 3.28Å; I240-Y242 PolarHBondContact O-N 3.12Å; Y242-R244 VanDerWaalsContact C-N 3.33Å; Y242-R244 PolarHBondContact O-N 3.48Å; Y242-M245 HydrophobicContact CD1-CE 3.81Å; Y242-M245 HydrophobicContact CE1-CE 3.98Å; Y242-M245 PolarHBondContact O-N 3.38Å; Y242-A246 VanDerWaalsContact O-CB 3.26Å; Y242-A246 WeakPolarHBondContact O-CB 3.4Å; Y242-A246 PolarHBondContact O-N 3.39Å; Y242-M272 HydrophobicContact CE1-CE 4.04Å; Y242-I273 HydrophobicContact CD1-CG1 3.82Å; Y242-I273 HydrophobicContact CD2-CB 4.25Å; Y242-I273 HydrophobicContact CD2-CG1 4.2Å; Y242-I273 HydrophobicContact CD2-CG2 3.77Å; Y242-I273 HydrophobicContact CE1-CG1 4.07Å; Y242-I273 HydrophobicContact CE2-CB 4.34Å; Y242-I273 HydrophobicContact CE2-CG1 4.42Å; Y242-I273 HydrophobicContact CE2-CG2 4.23Å; Y242-I273 HydrophobicContact CG-CB 4.41Å; Y242-I273 HydrophobicContact CG-CG1 3.88Å; Y242-I273 HydrophobicContact CG-CG2 4.07Å; Y242-V276 HydrophobicContact CE2-CB 3.8Å; Y242-V276 HydrophobicContact CE2-CG1 3.79Å; Y242-V276 WeakPolarHBondContact OH-CB 3.34Å; Y242-V276 WeakPolarHBondContact OH-CG1 3.03Å; Y242-V276 WeakPolarHBondContact OH-CG2 3.24Å
243	C	84.1	Confident	80.2	Confident	85 Å²	85	70.1 Å²	70.1	57%	0.574	38%	0.378	S	S	*	.	H	α-helix	trans	-59.9	-45	171.3	-70.1	0	0	0	0	111	M239 I240 A246 H247	M239-C243 WeakPolarHBondContact O-CB 3.3Å; M239-C243 PolarHBondContact O-N 3.29Å; M239-C243 PolarHBondContact O-SG 3.34Å; I240-C243 PolarHBondContact O-N 2.03Å; C243-A246 PolarHBondContact O-N 3.14Å; C243-H247 WeakPolarHBondContact O-CB 3.33Å; C243-H247 PolarHBondContact O-N 2.95Å
244	R	83.3	Confident	78	Confident	155 Å²	155	70.1 Å²	70.1	59%	0.585	39%	0.387	S	S	*	.	H	α-helix	trans	-64.3	-43.1	176.2	-66.1	-69	-179.2	-179.9	-0.3	111.8	Y155 I240 Y242 H247 I248	Y155-R244 HydrophobicContact CE2-CB 3.74Å; I240-R244 HydrophobicContact CG2-CG 4.44Å; I240-R244 WeakPolarHBondContact O-CB 3.43Å; I240-R244 VanDerWaalsContact O-CG 3.24Å; I240-R244 WeakPolarHBondContact O-CG 3.26Å; I240-R244 PolarHBondContact O-N 3.32Å; Y242-R244 VanDerWaalsContact C-N 3.33Å; Y242-R244 PolarHBondContact O-N 3.48Å; R244-H247 PolarHBondContact O-N 3.17Å; R244-I248 WeakPolarHBondContact O-CG1 3.33Å; R244-I248 PolarHBondContact O-N 3.33Å
245	M	77.4	Confident	75.5	Confident	0 Å²	0	80.5 Å²	80.5	0%	0	43%	0.427	C	S	.	.	H	α-helix	trans	-63.2	-46.6	176.9	-167.8	160.4	70.5	0	0	111.6	Y155 I158 C241 Y242 I248 L249 A269 I273	Y155-M245 HydrophobicContact CD2-CB 4.32Å; I158-M245 HydrophobicContact CD1-SD 3.65Å; C241-M245 VanDerWaalsContact O-CB 3.3Å; C241-M245 WeakPolarHBondContact O-CB 3.41Å; C241-M245 PolarHBondContact O-N 3.42Å; Y242-M245 HydrophobicContact CD1-CE 3.81Å; Y242-M245 HydrophobicContact CE1-CE 3.98Å; Y242-M245 PolarHBondContact O-N 3.38Å; M245-I248 PolarHBondContact O-N 3.06Å; M245-L249 HydrophobicContact CG-CD1 4.05Å; M245-L249 WeakPolarHBondContact O-CB 3.44Å; M245-L249 VanDerWaalsContact O-CD1 3.22Å; M245-L249 WeakPolarHBondContact O-CD1 3.41Å; M245-L249 PolarHBondContact O-N 3.33Å; M245-A269 HydrophobicContact CE-CB 4.25Å; M245-A269 HydrophobicContact SD-CB 4.14Å; M245-I273 HydrophobicContact CE-CD1 3.35Å; M245-I273 HydrophobicContact CE-CG1 3.17Å
246	A	77.3	Confident	73	Confident	40 Å²	40	86.3 Å²	86.3	33%	0.331	45%	0.454	S	S	.	.	H	α-helix	trans	-60.9	-45.7	177.2	0	0	0	0	0	111.6	Y242 C243 I248 L249 C250	Y242-A246 VanDerWaalsContact O-CB 3.26Å; Y242-A246 WeakPolarHBondContact O-CB 3.4Å; Y242-A246 PolarHBondContact O-N 3.39Å; C243-A246 PolarHBondContact O-N 3.14Å; A246-I248 VanDerWaalsContact C-N 3.34Å; A246-I248 PolarHBondContact O-N 2.99Å; A246-L249 PolarHBondContact O-N 2.91Å; A246-L249 VanDerWaalsContact O-N 3.12Å; A246-C250 WeakPolarHBondContact O-CB 3.44Å; A246-C250 PolarHBondContact O-N 3.24Å; A246-C250 PolarHBondContact O-SG 2.93Å
247	H	80.5	Confident	70.7	Confident	100 Å²	100	86.5 Å²	86.5	46%	0.463	48%	0.478	S	S	.	.	H	α-helix	trans	-59.5	-42.6	177.2	175.1	-92.1	0	0	0	112.3	C243 R244 L249 C250 R251	C243-H247 WeakPolarHBondContact O-CB 3.33Å; C243-H247 PolarHBondContact O-N 2.95Å; R244-H247 PolarHBondContact O-N 3.17Å; H247-L249 VanDerWaalsContact C-N 3.35Å; H247-C250 PolarHBondContact O-N 3.35Å; H247-R251 PolarHBondContact CE1-NE 3.44Å; H247-R251 VanDerWaalsContact CE1-NE 3.26Å; H247-R251 PolarHBondContact CE1-NH2 2.77Å; H247-R251 VanDerWaalsContact CE1-NH2 3.33Å; H247-R251 PolarHBondContact O-N 3.34Å
248	I	74.2	Confident	68.7	Low	80 Å²	80	89.4 Å²	89.4	41%	0.41	49%	0.49	S	S	.	.	H	α-helix	trans	-65.3	-39.6	175.5	-69.6	165.5	0	0	0	111.1	C159 R244 M245 A246 C250 R251	C159-I248 HydrophobicContact CB-CD1 3.98Å; C159-I248 WeakPolarHBondContact SG-CD1 3.41Å; R244-I248 WeakPolarHBondContact O-CG1 3.33Å; R244-I248 PolarHBondContact O-N 3.33Å; M245-I248 PolarHBondContact O-N 3.06Å; A246-I248 VanDerWaalsContact C-N 3.34Å; A246-I248 PolarHBondContact O-N 2.99Å; I248-C250 VanDerWaalsContact C-N 3.31Å; I248-C250 PolarHBondContact O-N 3.22Å; I248-R251 PolarHBondContact O-N 3.47Å
249	L	70.9	Confident	66.9	Low	24 Å²	24	95.1 Å²	95.1	13%	0.126	53%	0.53	C	S	.	.	H	α-helix	trans	-69.9	-25.4	179.7	-95.7	62.8	0	0	0	114	I158 M245 A246 H247 R266 A269 V270	I158-L249 HydrophobicContact CG2-CD1 4.26Å; M245-L249 HydrophobicContact CG-CD1 4.05Å; M245-L249 WeakPolarHBondContact O-CB 3.44Å; M245-L249 VanDerWaalsContact O-CD1 3.22Å; M245-L249 WeakPolarHBondContact O-CD1 3.41Å; M245-L249 PolarHBondContact O-N 3.33Å; A246-L249 PolarHBondContact O-N 2.91Å; A246-L249 VanDerWaalsContact O-N 3.12Å; H247-L249 VanDerWaalsContact C-N 3.35Å; L249-R266 HydrophobicContact CD2-CB 4.5Å; L249-R266 HydrophobicContact CD2-CG 3.62Å; L249-R266 HydrophobicContact CG-CG 3.78Å; L249-A269 HydrophobicContact CD2-CB 4.19Å; L249-V270 HydrophobicContact CD2-CG2 3.69Å
250	C	71.1	Confident	65.1	Low	107 Å²	107	95.4 Å²	95.4	72%	0.723	53%	0.534	S	S	*	.	H	α-helix	trans	-89.8	-9	179.4	-68	0	0	0	0	113.9	A246 H247 I248	A246-C250 WeakPolarHBondContact O-CB 3.44Å; A246-C250 PolarHBondContact O-N 3.24Å; A246-C250 PolarHBondContact O-SG 2.93Å; H247-C250 PolarHBondContact O-N 3.35Å; I248-C250 VanDerWaalsContact C-N 3.31Å; I248-C250 PolarHBondContact O-N 3.22Å
251	R	69.7	Low	63.5	Low	167 Å²	167	92.9 Å²	92.9	63%	0.63	53%	0.529	S	S	*	.	S	Bend	trans	-69.4	136.2	175.6	-75.8	-164.7	173.8	-161.3	-3.7	110.9	H247 I248	H247-R251 PolarHBondContact CE1-NE 3.44Å; H247-R251 VanDerWaalsContact CE1-NE 3.26Å; H247-R251 PolarHBondContact CE1-NH2 2.77Å; H247-R251 VanDerWaalsContact CE1-NH2 3.33Å; H247-R251 PolarHBondContact O-N 3.34Å; I248-R251 PolarHBondContact O-N 3.47Å
252	P	56.4	Low	62.4	Low	112 Å²	112	95.6 Å²	95.6	73%	0.727	55%	0.545	S	S	*	.			trans	-62.1	142.5	177.5	24.3	-31.3	0	0	0	110.4	S254	P252-S254 PolarHBondContact O-N 3.45Å
253	V	56.1	Low	61.5	Low	149 Å²	149	97.5 Å²	97.5	90%	0.903	57%	0.568	S	S	*	*	S	Bend	trans	-68.4	4.3	-173.4	178.9	0	0	0	0	113.2
254	S	47.5	Very low	60.6	Low	100 Å²	100	101.2 Å²	101.2	70%	0.699	58%	0.577	S	S	*	*			trans	-92.8	131.2	177.2	-83.5	0	0	0	0	111.1	P252	P252-S254 PolarHBondContact O-N 3.45Å
255	Y	38.3	Very low	59.7	Low	223 Å²	223	99.7 Å²	99.7	88%	0.875	57%	0.574	S	S	*	*	S	Bend	trans	93.8	118.3	176.3	-96.8	-103.8	0	0	0	117.5
256	H	38.8	Very low	59.3	Low	167 Å²	167	105.8 Å²	105.8	77%	0.773	60%	0.597	S	S	*	*	S	Bend	trans	76.3	107.2	-170.7	-69.6	-22.2	0	0	0	115.2	V258	H256-V258 PolarHBondContact O-N 3.03Å
257	G	41.4	Very low	59	Low	93 Å²	93	107.6 Å²	107.6	96%	0.959	60%	0.601	S	S	*	*			trans	-61.5	49.2	179.5	0	0	0	0	0	115.5
258	V	46.3	Very low	58.5	Low	88 Å²	88	106.3 Å²	106.3	53%	0.533	59%	0.593	S	S	.	*			trans	-103.2	99.3	165.9	-152.1	0	0	0	0	106.3	F162 H256 V260	F162-V258 HydrophobicContact CE2-CG1 4.48Å; H256-V258 PolarHBondContact O-N 3.03Å; V258-V260 VanDerWaalsContact C-N 3.28Å; V258-V260 HydrophobicContact CB-CG2 3.5Å; V258-V260 VanDerWaalsContact CB-CG2 3.5Å; V258-V260 HydrophobicContact CG1-CG2 3.05Å; V258-V260 WeakPolarHBondContact O-CG2 3.49Å; V258-V260 PolarHBondContact O-N 3.07Å
259	S	50.8	Low	58.4	Low	121 Å²	121	102.6 Å²	102.6	85%	0.846	57%	0.574	S	S	*	*			trans	-64.2	83.5	167.4	154	0	0	0	0	109.4
260	V	49.3	Very low	58.5	Low	59 Å²	59	104.4 Å²	104.4	36%	0.358	59%	0.585	S	S	.	*			trans	-101.3	-22.8	-169	-172.6	0	0	0	0	115.8	P161 V258	P161-V260 HydrophobicContact CG-CG1 4.17Å; V258-V260 VanDerWaalsContact C-N 3.28Å; V258-V260 HydrophobicContact CB-CG2 3.5Å; V258-V260 VanDerWaalsContact CB-CG2 3.5Å; V258-V260 HydrophobicContact CG1-CG2 3.05Å; V258-V260 WeakPolarHBondContact O-CG2 3.49Å; V258-V260 PolarHBondContact O-N 3.07Å
261	A	52.4	Low	58.7	Low	51 Å²	51	103 Å²	103	42%	0.421	57%	0.565	S	S	.	*			trans	-141.4	97.3	176.7	0	0	0	0	0	112.8	G263	A261-G263 PolarHBondContact O-N 2.82Å
262	T	62.2	Low	59.1	Low	77 Å²	77	95.4 Å²	95.4	47%	0.472	54%	0.537	S	S	.	.			trans	-44.1	136.3	156.8	51.7	0	0	0	0	108.9	E264 K265 R266	T262-E264 PolarHBondContact O-N 2.85Å; T262-K265 WeakPolarHBondContact O-CB 3.3Å; T262-K265 PolarHBondContact O-N 3.18Å; T262-K265 WeakPolarHBondContact OG1-CD 3.36Å; T262-K265 VanDerWaalsContact OG1-CG 3.28Å; T262-K265 WeakPolarHBondContact OG1-CG 3.5Å; T262-R266 PolarHBondContact O-N 2.98Å
263	G	63.2	Low	60.2	Low	50 Å²	50	91.5 Å²	91.5	52%	0.515	51%	0.51	S	S	.	.	H	α-helix	trans	-47.8	-33.1	-177.3	0	0	0	0	0	114.2	A261 K265 R266 D267	A261-G263 PolarHBondContact O-N 2.82Å; G263-K265 PolarHBondContact O-N 2.93Å; G263-R266 PolarHBondContact O-N 3.18Å; G263-D267 WeakPolarHBondContact O-CB 3.06Å; G263-D267 PolarHBondContact O-N 3.01Å
264	E	65.4	Low	61.3	Low	162 Å²	162	89.8 Å²	89.8	76%	0.757	50%	0.495	S	S	*	.	H	α-helix	trans	-62.7	-35.3	174.1	-60.6	-166.8	141.1	0	0	115.1	T262 R268	T262-E264 PolarHBondContact O-N 2.85Å; E264-R268 WeakPolarHBondContact O-CB 3.33Å; E264-R268 PolarHBondContact O-N 2.73Å; E264-R268 VanDerWaalsContact O-N 3.11Å
265	K	65.1	Low	62.9	Low	123 Å²	123	85.5 Å²	85.5	54%	0.535	46%	0.464	S	S	.	.	H	α-helix	trans	-71.9	-40.4	177.2	-76.4	176.6	-175.1	177.9	0	110.5	T262 G263 A269	T262-K265 WeakPolarHBondContact O-CB 3.3Å; T262-K265 PolarHBondContact O-N 3.18Å; T262-K265 WeakPolarHBondContact OG1-CD 3.36Å; T262-K265 VanDerWaalsContact OG1-CG 3.28Å; T262-K265 WeakPolarHBondContact OG1-CG 3.5Å; G263-K265 PolarHBondContact O-N 2.93Å; K265-A269 PolarHBondContact O-N 3.03Å; K265-A269 VanDerWaalsContact O-N 3.08Å
266	R	69.4	Low	65	Low	128 Å²	128	74.9 Å²	74.9	48%	0.483	42%	0.422	S	S	.	.	H	α-helix	trans	-62.5	-52.1	175.4	177.7	171.8	78.7	174.9	3.6	111.3	L249 T262 G263 R268 A269 V270	L249-R266 HydrophobicContact CD2-CB 4.5Å; L249-R266 HydrophobicContact CD2-CG 3.62Å; L249-R266 HydrophobicContact CG-CG 3.78Å; T262-R266 PolarHBondContact O-N 2.98Å; G263-R266 PolarHBondContact O-N 3.18Å; R266-R268 VanDerWaalsContact C-N 3.32Å; R266-R268 PolarHBondContact O-N 3.27Å; R266-A269 WeakPolarHBondContact O-CA 3.49Å; R266-A269 WeakPolarHBondContact O-CB 3.27Å; R266-A269 PolarHBondContact O-N 3.16Å; R266-V270 WeakPolarHBondContact O-CG2 3.07Å; R266-V270 PolarHBondContact O-N 3.23Å
267	D	69.6	Low	67.2	Low	78 Å²	78	68.2 Å²	68.2	42%	0.417	40%	0.397	S	S	.	.	H	α-helix	trans	-59.4	-42.2	178.7	170.2	65.3	0	0	0	111.8	G263 A269 V270 R271	G263-D267 WeakPolarHBondContact O-CB 3.06Å; G263-D267 PolarHBondContact O-N 3.01Å; D267-A269 VanDerWaalsContact C-N 3.29Å; D267-A269 PolarHBondContact O-N 3.46Å; D267-V270 PolarHBondContact O-N 2.94Å; D267-R271 WeakPolarHBondContact O-CB 3.23Å; D267-R271 PolarHBondContact O-N 3.14Å; D267-R271 IonicContact OD1-NH2 3.67Å; D267-R271 IonicContact OD2-CZ 3.63Å; D267-R271 IonicContact OD2-NE 3.06Å; D267-R271 IonicContact OD2-NH2 2.62Å; D267-R271 PolarHBondContact OD2-NH2 2.93Å
268	R	71.4	Confident	69.2	Low	74 Å²	74	65.9 Å²	65.9	28%	0.279	37%	0.368	S	S	.	.	H	α-helix	trans	-59.1	-39.6	172.5	-179.5	179.5	-71.9	169.4	4.7	112.7	E264 R266 M272	E264-R268 WeakPolarHBondContact O-CB 3.33Å; E264-R268 PolarHBondContact O-N 2.73Å; E264-R268 VanDerWaalsContact O-N 3.11Å; R266-R268 VanDerWaalsContact C-N 3.32Å; R266-R268 PolarHBondContact O-N 3.27Å; R268-M272 PolarHBondContact O-N 3.43Å; R268-M272 VanDerWaalsContact O-N 3.15Å
269	A	70.2	Confident	71.2	Confident	2 Å²	2	61.7 Å²	61.7	2%	0.017	34%	0.343	C	S	.	.	H	α-helix	trans	-68.1	-50.4	-179.3	0	0	0	0	0	111.6	I158 M245 L249 K265 R266 D267 R271 M272 I273	I158-A269 HydrophobicContact CD1-CB 3.41Å; I158-A269 VanDerWaalsContact CD1-CB 3.41Å; M245-A269 HydrophobicContact CE-CB 4.25Å; M245-A269 HydrophobicContact SD-CB 4.14Å; L249-A269 HydrophobicContact CD2-CB 4.19Å; K265-A269 PolarHBondContact O-N 3.03Å; K265-A269 VanDerWaalsContact O-N 3.08Å; R266-A269 WeakPolarHBondContact O-CA 3.49Å; R266-A269 WeakPolarHBondContact O-CB 3.27Å; R266-A269 PolarHBondContact O-N 3.16Å; D267-A269 VanDerWaalsContact C-N 3.29Å; D267-A269 PolarHBondContact O-N 3.46Å; A269-R271 VanDerWaalsContact C-N 3.29Å; A269-R271 PolarHBondContact O-N 3.42Å; A269-M272 WeakPolarHBondContact O-CB 3.31Å; A269-M272 PolarHBondContact O-N 3.37Å; A269-M272 VanDerWaalsContact O-N 3.09Å; A269-I273 WeakPolarHBondContact O-CG1 3.49Å; A269-I273 PolarHBondContact O-N 2.88Å
270	V	73.5	Confident	73	Confident	61 Å²	61	56 Å²	56	37%	0.37	30%	0.303	S	S	.	.	H	α-helix	trans	-56	-47	176.4	173.6	0	0	0	0	110.5	L249 R266 D267 M272 I273 L274	L249-V270 HydrophobicContact CD2-CG2 3.69Å; R266-V270 WeakPolarHBondContact O-CG2 3.07Å; R266-V270 PolarHBondContact O-N 3.23Å; D267-V270 PolarHBondContact O-N 2.94Å; V270-M272 PolarHBondContact O-N 2.87Å; V270-I273 WeakPolarHBondContact O-CB 3.38Å; V270-I273 PolarHBondContact O-N 3Å; V270-I273 VanDerWaalsContact O-N 3.12Å; V270-L274 HydrophobicContact CG1-CD1 4.17Å; V270-L274 HydrophobicContact CG1-CG 4.45Å; V270-L274 WeakPolarHBondContact O-CG 3.06Å; V270-L274 PolarHBondContact O-N 2.84Å
271	R	76.8	Confident	74.8	Confident	77 Å²	77	56.6 Å²	56.6	29%	0.291	31%	0.309	S	S	.	.	H	α-helix	trans	-60.6	-35.6	179.2	-159.5	-163.8	-56.7	-116.8	-0.3	113	D267 A269 V275 T336	D267-R271 WeakPolarHBondContact O-CB 3.23Å; D267-R271 PolarHBondContact O-N 3.14Å; D267-R271 IonicContact OD1-NH2 3.67Å; D267-R271 IonicContact OD2-CZ 3.63Å; D267-R271 IonicContact OD2-NE 3.06Å; D267-R271 IonicContact OD2-NH2 2.62Å; D267-R271 PolarHBondContact OD2-NH2 2.93Å; A269-R271 VanDerWaalsContact C-N 3.29Å; A269-R271 PolarHBondContact O-N 3.42Å; R271-V275 PolarHBondContact O-N 3.38Å; R271-V275 VanDerWaalsContact O-N 3.1Å; R271-T336 VanDerWaalsContact CD-CB 3.41Å; R271-T336 VanDerWaalsContact CD-CG2 3.41Å; R271-T336 WeakPolarHBondContact CD-O 3.32Å; R271-T336 HydrophobicContact CG-CG2 3.45Å; R271-T336 VanDerWaalsContact CG-CG2 3.45Å
272	M	76.1	Confident	76.6	Confident	8 Å²	8	57.4 Å²	57.4	4%	0.039	31%	0.308	C	S	.	.	H	α-helix	trans	-72.2	-39.5	175.5	-165.5	-168.6	76.7	0	0	112.2	I150 R154 Y242 R268 A269 V270 L274 V275 V276	I150-M272 HydrophobicContact CG2-SD 4.15Å; R154-M272 HydrophobicContact CB-CE 3.39Å; R154-M272 HydrophobicContact CB-SD 3.83Å; R154-M272 VanDerWaalsContact CD-SD 3.57Å; R154-M272 HydrophobicContact CG-CE 3.66Å; R154-M272 HydrophobicContact CG-SD 3.34Å; R154-M272 WeakPolarHBondContact CG-SD 3.47Å; R154-M272 PolarHBondContact NE-SD 3.37Å; R154-M272 VanDerWaalsContact NE-SD 3.42Å; Y242-M272 HydrophobicContact CE1-CE 4.04Å; R268-M272 PolarHBondContact O-N 3.43Å; R268-M272 VanDerWaalsContact O-N 3.15Å; A269-M272 WeakPolarHBondContact O-CB 3.31Å; A269-M272 PolarHBondContact O-N 3.37Å; A269-M272 VanDerWaalsContact O-N 3.09Å; V270-M272 PolarHBondContact O-N 2.87Å; M272-L274 VanDerWaalsContact C-N 3.31Å; M272-L274 PolarHBondContact O-N 3.44Å; M272-V275 PolarHBondContact O-N 3.29Å; M272-V276 HydrophobicContact CG-CG2 4.49Å; M272-V276 WeakPolarHBondContact O-CG2 3.24Å; M272-V276 PolarHBondContact O-N 3.23Å
273	I	79.6	Confident	78	Confident	31 Å²	31	53.7 Å²	53.7	16%	0.159	29%	0.286	C	S	.	.	H	α-helix	trans	-54.7	-51.8	171.4	-64.9	172.7	0	0	0	109.3	Y242 M245 A269 V270 V275 V276 A277	Y242-I273 HydrophobicContact CD1-CG1 3.82Å; Y242-I273 HydrophobicContact CD2-CB 4.25Å; Y242-I273 HydrophobicContact CD2-CG1 4.2Å; Y242-I273 HydrophobicContact CD2-CG2 3.77Å; Y242-I273 HydrophobicContact CE1-CG1 4.07Å; Y242-I273 HydrophobicContact CE2-CB 4.34Å; Y242-I273 HydrophobicContact CE2-CG1 4.42Å; Y242-I273 HydrophobicContact CE2-CG2 4.23Å; Y242-I273 HydrophobicContact CG-CB 4.41Å; Y242-I273 HydrophobicContact CG-CG1 3.88Å; Y242-I273 HydrophobicContact CG-CG2 4.07Å; M245-I273 HydrophobicContact CE-CD1 3.35Å; M245-I273 HydrophobicContact CE-CG1 3.17Å; A269-I273 WeakPolarHBondContact O-CG1 3.49Å; A269-I273 PolarHBondContact O-N 2.88Å; V270-I273 WeakPolarHBondContact O-CB 3.38Å; V270-I273 PolarHBondContact O-N 3Å; V270-I273 VanDerWaalsContact O-N 3.12Å; I273-V275 VanDerWaalsContact C-N 3.33Å; I273-V275 PolarHBondContact O-N 3.34Å; I273-V276 PolarHBondContact O-N 3.1Å; I273-A277 WeakPolarHBondContact O-CB 3.28Å; I273-A277 PolarHBondContact O-N 3.09Å
274	L	80.1	Confident	79.4	Confident	113 Å²	113	51.3 Å²	51.3	59%	0.592	26%	0.261	S	S	*	.	H	α-helix	trans	-59.7	-42.6	-177.8	-68.9	175.3	0	0	0	112	V270 M272 A278	V270-L274 HydrophobicContact CG1-CD1 4.17Å; V270-L274 HydrophobicContact CG1-CG 4.45Å; V270-L274 WeakPolarHBondContact O-CG 3.06Å; V270-L274 PolarHBondContact O-N 2.84Å; M272-L274 VanDerWaalsContact C-N 3.31Å; M272-L274 PolarHBondContact O-N 3.44Å; L274-A278 VanDerWaalsContact O-CB 3.25Å; L274-A278 WeakPolarHBondContact O-CB 3.39Å; L274-A278 PolarHBondContact O-N 3.18Å
275	V	81.1	Confident	80.8	Confident	9 Å²	9	46.8 Å²	46.8	6%	0.055	24%	0.242	C	C	.	.	H	α-helix	trans	-62.7	-52.9	176.5	158.5	0	0	0	0	112	R271 M272 I273 A277 A278 V279 L332 T336	R271-V275 PolarHBondContact O-N 3.38Å; R271-V275 VanDerWaalsContact O-N 3.1Å; M272-V275 PolarHBondContact O-N 3.29Å; I273-V275 VanDerWaalsContact C-N 3.33Å; I273-V275 PolarHBondContact O-N 3.34Å; V275-A277 VanDerWaalsContact C-N 3.31Å; V275-A277 PolarHBondContact O-N 3.13Å; V275-A278 PolarHBondContact O-N 3.22Å; V275-V279 WeakPolarHBondContact O-CG2 3.33Å; V275-V279 PolarHBondContact O-N 2.87Å; V275-L332 HydrophobicContact CB-CB 4.32Å; V275-L332 HydrophobicContact CG1-CB 3.54Å; V275-L332 HydrophobicContact CG1-CD1 4.15Å; V275-L332 HydrophobicContact CG1-CG 4.4Å; V275-L332 HydrophobicContact CG2-CB 3.84Å; V275-L332 HydrophobicContact CG2-CD2 4.22Å; V275-L332 HydrophobicContact CG2-CG 4.49Å; V275-T336 HydrophobicContact CB-CG2 4.44Å; V275-T336 HydrophobicContact CG2-CG2 3.22Å
276	V	82.1	Confident	82.2	Confident	0 Å²	0	42.5 Å²	42.5	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-64.7	-42.7	-175.9	172.3	0	0	0	0	109.5	L147 V238 Y242 M272 I273 A278 V279 F280	L147-V276 HydrophobicContact CD2-CG2 4.43Å; V238-V276 HydrophobicContact CG1-CG1 3.99Å; Y242-V276 HydrophobicContact CE2-CB 3.8Å; Y242-V276 HydrophobicContact CE2-CG1 3.79Å; Y242-V276 WeakPolarHBondContact OH-CB 3.34Å; Y242-V276 WeakPolarHBondContact OH-CG1 3.03Å; Y242-V276 WeakPolarHBondContact OH-CG2 3.24Å; M272-V276 HydrophobicContact CG-CG2 4.49Å; M272-V276 WeakPolarHBondContact O-CG2 3.24Å; M272-V276 PolarHBondContact O-N 3.23Å; I273-V276 PolarHBondContact O-N 3.1Å; V276-A278 PolarHBondContact O-N 3.18Å; V276-V279 PolarHBondContact O-N 3.45Å; V276-F280 HydrophobicContact CG1-CD2 3.63Å; V276-F280 HydrophobicContact CG1-CE2 3.64Å; V276-F280 VanDerWaalsContact O-CD2 3.29Å; V276-F280 WeakPolarHBondContact O-CD2 3.33Å; V276-F280 PolarHBondContact O-N 2.78Å
277	A	84.4	Confident	83.4	Confident	28 Å²	28	36.4 Å²	36.4	23%	0.231	20%	0.203	C	C	.	.	H	α-helix	trans	-56.8	-46.8	173	0	0	0	0	0	112	I273 V275 V279 F280 C281	I273-A277 WeakPolarHBondContact O-CB 3.28Å; I273-A277 PolarHBondContact O-N 3.09Å; V275-A277 VanDerWaalsContact C-N 3.31Å; V275-A277 PolarHBondContact O-N 3.13Å; A277-V279 PolarHBondContact O-N 2.84Å; A277-F280 PolarHBondContact O-N 3.08Å; A277-C281 WeakPolarHBondContact O-CB 3.39Å; A277-C281 PolarHBondContact O-N 2.93Å; A277-C281 PolarHBondContact O-SG 2.65Å
278	A	85	Confident	84.7	Confident	43 Å²	43	32.8 Å²	32.8	36%	0.355	18%	0.184	S	C	.	.	H	α-helix	trans	-60.1	-44	177.2	0	0	0	0	0	112.2	L274 V275 V276 C281 V282	L274-A278 VanDerWaalsContact O-CB 3.25Å; L274-A278 WeakPolarHBondContact O-CB 3.39Å; L274-A278 PolarHBondContact O-N 3.18Å; V275-A278 PolarHBondContact O-N 3.22Å; V276-A278 PolarHBondContact O-N 3.18Å; A278-C281 PolarHBondContact O-N 3.23Å; A278-V282 VanDerWaalsContact O-CB 3.28Å; A278-V282 WeakPolarHBondContact O-CB 3.34Å; A278-V282 VanDerWaalsContact O-CG2 3.31Å; A278-V282 WeakPolarHBondContact O-CG2 3.42Å; A278-V282 PolarHBondContact O-N 3.01Å
279	V	87	Confident	85.9	Confident	1 Å²	1	33.5 Å²	33.5	1%	0.006	19%	0.193	C	C	.	.	H	α-helix	trans	-62.2	-45.6	176.7	176.8	0	0	0	0	110.9	L147 V275 V276 A277 S283 F284 D329 L332	L147-V279 HydrophobicContact CD1-CG1 3.99Å; V275-V279 WeakPolarHBondContact O-CG2 3.33Å; V275-V279 PolarHBondContact O-N 2.87Å; V276-V279 PolarHBondContact O-N 3.45Å; A277-V279 PolarHBondContact O-N 2.84Å; V279-S283 WeakPolarHBondContact O-CA 2.95Å; V279-S283 WeakPolarHBondContact O-CB 3.17Å; V279-S283 PolarHBondContact O-N 2.65Å; V279-S283 PolarHBondContact O-OG 2.93Å; V279-F284 HydrophobicContact CG1-CD2 4.26Å; V279-F284 HydrophobicContact CG1-CE2 3.53Å; V279-F284 HydrophobicContact CG1-CZ 3.75Å; V279-D329 WeakPolarHBondContact CG1-OD1 3.3Å; V279-D329 VanDerWaalsContact CG2-OD1 3.28Å; V279-D329 WeakPolarHBondContact CG2-OD1 3.42Å; V279-L332 HydrophobicContact CG2-CD1 3.4Å
280	F	88.9	Confident	87.1	Confident	1 Å²	1	34 Å²	34	0%	0.004	20%	0.195	C	C	.	.	I	π-helix	trans	-62.2	-46.4	177.4	-89.8	-85.6	0	0	0	112.2	I144 L147 F231 F235 V238 V276 A277 F284 L285	I144-F280 HydrophobicContact CG1-CE1 4.28Å; I144-F280 HydrophobicContact CG2-CE1 4.02Å; I144-F280 HydrophobicContact CG2-CZ 4.02Å; L147-F280 HydrophobicContact CB-CE2 4.36Å; F231-F280 HydrophobicContact CE2-CD1 4.02Å; F231-F280 HydrophobicContact CE2-CE1 4.35Å; F235-F280 HydrophobicContact CB-CD1 4.5Å; F235-F280 HydrophobicContact CB-CE1 4.18Å; F235-F280 HydrophobicContact CD2-CB 4.38Å; F235-F280 AromaticContact CD2-CD1 3.52Å; F235-F280 HydrophobicContact CD2-CD1 3.52Å; F235-F280 AromaticContact CD2-CE1 3.96Å; F235-F280 HydrophobicContact CD2-CE1 3.96Å; F235-F280 HydrophobicContact CD2-CG 4.05Å; F235-F280 HydrophobicContact CE2-CB 4.28Å; F235-F280 HydrophobicContact CE2-CD1 4.24Å; F235-F280 HydrophobicContact CE2-CG 4.42Å; F235-F280 HydrophobicContact CG-CD1 4.46Å; V238-F280 HydrophobicContact CG2-CE2 4.36Å; V238-F280 HydrophobicContact CG2-CZ 4.36Å; V276-F280 HydrophobicContact CG1-CD2 3.63Å; V276-F280 HydrophobicContact CG1-CE2 3.64Å; V276-F280 VanDerWaalsContact O-CD2 3.29Å; V276-F280 WeakPolarHBondContact O-CD2 3.33Å; V276-F280 PolarHBondContact O-N 2.78Å; A277-F280 PolarHBondContact O-N 3.08Å; F280-F284 HydrophobicContact CB-CD2 4.43Å; F280-F284 HydrophobicContact CD1-CB 4.31Å; F280-F284 AromaticContact CD1-CD2 3.68Å; F280-F284 HydrophobicContact CD1-CD2 3.68Å; F280-F284 HydrophobicContact CD1-CG 4.48Å; F280-F284 HydrophobicContact CD2-CD2 4.33Å; F280-F284 AromaticContact CE1-CD2 3.96Å; F280-F284 HydrophobicContact CE1-CD2 3.96Å; F280-F284 AromaticContact CG-CD2 3.89Å; F280-F284 HydrophobicContact CG-CD2 3.89Å; F280-F284 HydrophobicContact CZ-CD2 4.4Å; F280-F284 PolarHBondContact O-N 2.79Å; F280-L285 WeakPolarHBondContact O-CB 3.39Å; F280-L285 PolarHBondContact O-N 3.29Å
281	C	88.3	Confident	88.2	Confident	72 Å²	72	31 Å²	31	49%	0.486	18%	0.178	S	C	.	.	I	π-helix	trans	-69.2	-39.3	-178.3	-69.9	0	0	0	0	113	A277 A278 P286	A277-C281 WeakPolarHBondContact O-CB 3.39Å; A277-C281 PolarHBondContact O-N 2.93Å; A277-C281 PolarHBondContact O-SG 2.65Å; A278-C281 PolarHBondContact O-N 3.23Å; C281-P286 WeakPolarHBondContact O-CD 3.33Å; C281-P286 VanDerWaalsContact O-CG 3.29Å; C281-P286 WeakPolarHBondContact O-CG 3.4Å
282	V	88.8	Confident	89.2	Confident	67 Å²	67	28.9 Å²	28.9	41%	0.406	17%	0.173	S	C	.	.	I	π-helix	trans	-85.3	-44.5	-176.9	176.2	0	0	0	0	111.1	A278 F321	A278-V282 VanDerWaalsContact O-CB 3.28Å; A278-V282 WeakPolarHBondContact O-CB 3.34Å; A278-V282 VanDerWaalsContact O-CG2 3.31Å; A278-V282 WeakPolarHBondContact O-CG2 3.42Å; A278-V282 PolarHBondContact O-N 3.01Å; V282-F321 HydrophobicContact CG1-CD1 4.4Å; V282-F321 VanDerWaalsContact O-CB 3.27Å; V282-F321 WeakPolarHBondContact O-CB 3.44Å
283	S	91.4	Very high	90.1	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	19%	0.19	C	C	.	.	I	π-helix	trans	-97	-44.4	-168	-47.3	0	0	0	0	113.2	V279 F321 A322	V279-S283 WeakPolarHBondContact O-CA 2.95Å; V279-S283 WeakPolarHBondContact O-CB 3.17Å; V279-S283 PolarHBondContact O-N 2.65Å; V279-S283 PolarHBondContact O-OG 2.93Å; S283-F321 VanDerWaalsContact CA-O 3.3Å; S283-F321 WeakPolarHBondContact CA-O 3.23Å; S283-F321 VanDerWaalsContact CB-O 3.27Å; S283-F321 WeakPolarHBondContact CB-O 3.31Å; S283-F321 CarbonylContact O-C 3.57Å; S283-A322 WeakPolarHBondContact O-CA 3.06Å; S283-A322 PolarHBondContact O-N 3.2Å
284	F	93.7	Very high	90.9	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	19%	0.188	C	C	.	.	I	π-helix	trans	-97.1	-50.5	-168	-54.9	-39.4	0	0	0	113.7	L140 I144 L147 F231 V279 F280 F287 H288 N325	L140-F284 HydrophobicContact CD1-CD1 3.43Å; L140-F284 VanDerWaalsContact CD1-CD1 3.43Å; L140-F284 HydrophobicContact CD1-CE1 3.83Å; L140-F284 HydrophobicContact CD1-CG 4.44Å; I144-F284 HydrophobicContact CD1-CB 4.39Å; I144-F284 HydrophobicContact CD1-CD1 4.32Å; I144-F284 HydrophobicContact CD1-CD2 4.4Å; I144-F284 HydrophobicContact CD1-CG 4.12Å; I144-F284 HydrophobicContact CG1-CD1 4.16Å; I144-F284 HydrophobicContact CG1-CD2 3.67Å; I144-F284 HydrophobicContact CG1-CE1 4.28Å; I144-F284 HydrophobicContact CG1-CE2 3.81Å; I144-F284 HydrophobicContact CG1-CG 3.87Å; I144-F284 HydrophobicContact CG1-CZ 4.13Å; L147-F284 HydrophobicContact CD1-CE2 3.61Å; L147-F284 HydrophobicContact CD1-CZ 4Å; F231-F284 HydrophobicContact CD2-CB 4.15Å; F231-F284 HydrophobicContact CE2-CB 3.81Å; V279-F284 HydrophobicContact CG1-CD2 4.26Å; V279-F284 HydrophobicContact CG1-CE2 3.53Å; V279-F284 HydrophobicContact CG1-CZ 3.75Å; F280-F284 HydrophobicContact CB-CD2 4.43Å; F280-F284 HydrophobicContact CD1-CB 4.31Å; F280-F284 AromaticContact CD1-CD2 3.68Å; F280-F284 HydrophobicContact CD1-CD2 3.68Å; F280-F284 HydrophobicContact CD1-CG 4.48Å; F280-F284 HydrophobicContact CD2-CD2 4.33Å; F280-F284 AromaticContact CE1-CD2 3.96Å; F280-F284 HydrophobicContact CE1-CD2 3.96Å; F280-F284 AromaticContact CG-CD2 3.89Å; F280-F284 HydrophobicContact CG-CD2 3.89Å; F280-F284 HydrophobicContact CZ-CD2 4.4Å; F280-F284 PolarHBondContact O-N 2.79Å; F284-F287 PolarHBondContact O-N 2.83Å; F284-H288 PolarHBondContact O-CD2 3.36Å; F284-H288 PolarHBondContact O-N 3.2Å; F284-N325 HydrophobicContact CE1-CB 3.75Å; F284-N325 WeakPolarHBondContact CE1-ND2 3.37Å; F284-N325 HydrophobicContact CZ-CB 3.89Å
285	L	93.8	Very high	91.6	Very high	67 Å²	67	26.8 Å²	26.8	35%	0.351	16%	0.159	S	C	.	.	H	α-helix	trans	-58.3	-46.5	-174.9	178.1	65.1	0	0	0	112.7	F231 F280 F287 H288 L289	F231-L285 HydrophobicContact CE1-CD1 4.13Å; F231-L285 HydrophobicContact CZ-CB 4.12Å; F231-L285 HydrophobicContact CZ-CD1 3.78Å; F280-L285 WeakPolarHBondContact O-CB 3.39Å; F280-L285 PolarHBondContact O-N 3.29Å; L285-F287 VanDerWaalsContact C-N 3.31Å; L285-F287 PolarHBondContact O-N 2.98Å; L285-H288 PolarHBondContact O-N 3.21Å; L285-L289 VanDerWaalsContact O-CB 3.24Å; L285-L289 WeakPolarHBondContact O-CB 3.29Å; L285-L289 PolarHBondContact O-N 2.93Å
286	P	94.9	Very high	92.3	Very high	33 Å²	33	28.9 Å²	28.9	21%	0.214	17%	0.172	C	C	.	.	H	α-helix	trans	-61.4	-42.1	-179.1	-23.6	36.3	0	0	0	111.6	C281 T290 T318	C281-P286 WeakPolarHBondContact O-CD 3.33Å; C281-P286 VanDerWaalsContact O-CG 3.29Å; C281-P286 WeakPolarHBondContact O-CG 3.4Å; P286-T290 WeakPolarHBondContact O-CB 3.4Å; P286-T290 VanDerWaalsContact O-CG2 3.24Å; P286-T290 WeakPolarHBondContact O-CG2 3.33Å; P286-T290 PolarHBondContact O-N 3.09Å; P286-T290 VanDerWaalsContact O-N 3.12Å; P286-T290 PolarHBondContact O-OG1 2.89Å; P286-T318 HydrophobicContact CB-CG2 4.12Å
287	F	95.4	Very high	92.8	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-64.5	-50.5	177.6	173	-100.6	0	0	0	112	F136 Y137 L140 F284 L285 L289 T290 K291 Y315 R319 A322	F136-F287 HydrophobicContact CE1-CE1 4.15Å; F136-F287 AromaticContact CE1-CE2 3.93Å; F136-F287 HydrophobicContact CE1-CE2 3.93Å; F136-F287 AromaticContact CE1-CZ 3.51Å; F136-F287 HydrophobicContact CE1-CZ 3.51Å; F136-F287 HydrophobicContact CZ-CD2 4.32Å; F136-F287 HydrophobicContact CZ-CE1 4.29Å; F136-F287 AromaticContact CZ-CE2 3.72Å; F136-F287 HydrophobicContact CZ-CE2 3.72Å; F136-F287 AromaticContact CZ-CZ 3.71Å; F136-F287 HydrophobicContact CZ-CZ 3.71Å; Y137-F287 HydrophobicContact CE1-CE1 4.43Å; Y137-F287 HydrophobicContact CE1-CZ 4.2Å; L140-F287 HydrophobicContact CD2-CD1 3.55Å; L140-F287 HydrophobicContact CD2-CE1 3.27Å; L140-F287 HydrophobicContact CD2-CZ 4.24Å; F284-F287 PolarHBondContact O-N 2.83Å; L285-F287 VanDerWaalsContact C-N 3.31Å; L285-F287 PolarHBondContact O-N 2.98Å; F287-L289 PolarHBondContact O-N 3.48Å; F287-T290 PolarHBondContact O-N 2.82Å; F287-T290 PolarHBondContact O-OG1 3.3Å; F287-K291 HydrophobicContact CE1-CD 4.12Å; F287-K291 HydrophobicContact CZ-CB 4.45Å; F287-K291 HydrophobicContact CZ-CD 4Å; F287-K291 HydrophobicContact CZ-CG 4.44Å; F287-K291 WeakPolarHBondContact O-CB 3.3Å; F287-K291 PolarHBondContact O-N 3.44Å; F287-Y315 HydrophobicContact CD2-CE2 4.3Å; F287-Y315 HydrophobicContact CE2-CD2 4.48Å; F287-Y315 AromaticContact CE2-CE2 3.65Å; F287-Y315 HydrophobicContact CE2-CE2 3.65Å; F287-Y315 HydrophobicContact CZ-CE2 4.31Å; F287-R319 HydrophobicContact CD2-CB 4.27Å; F287-R319 HydrophobicContact CD2-CG 4.29Å; F287-R319 HydrophobicContact CE2-CB 4.39Å; F287-R319 HydrophobicContact CE2-CG 4.06Å; F287-A322 HydrophobicContact CB-CB 3.95Å; F287-A322 HydrophobicContact CD1-CB 4.39Å; F287-A322 HydrophobicContact CD2-CB 4.29Å; F287-A322 HydrophobicContact CG-CB 3.94Å
288	H	96.3	Very high	93.1	Very high	2 Å²	2	29 Å²	29	1%	0.009	17%	0.167	C	C	.	.	H	α-helix	trans	-65.6	-40.4	-177.2	-78.3	-68.6	0	0	0	112.7	H141 T227 F231 F284 L285 T292	H141-H288 AromaticContact CE1-CE1 3.61Å; T227-H288 HydrophobicContact CG2-CB 4.38Å; F231-H288 HydrophobicContact CD1-CB 3.64Å; F231-H288 AromaticContact CD1-CD2 3.94Å; F231-H288 AromaticContact CD1-CG 3.7Å; F231-H288 HydrophobicContact CD2-CB 4.42Å; F231-H288 AromaticContact CD2-CD2 3.24Å; F231-H288 WeakPolarHBondContact CD2-CD2 3.21Å; F231-H288 AromaticContact CD2-CG 3.89Å; F231-H288 AromaticContact CD2-NE2 3.81Å; F231-H288 HydrophobicContact CE1-CB 3.85Å; F231-H288 AromaticContact CE2-CD2 3.84Å; F231-H288 HydrophobicContact CG-CB 3.95Å; F231-H288 AromaticContact CG-CD2 3.29Å; F231-H288 WeakPolarHBondContact CG-CD2 3.27Å; F231-H288 AromaticContact CG-CG 3.47Å; F231-H288 VanDerWaalsContact CG-CG 3.47Å; F231-H288 AromaticContact CG-NE2 3.8Å; F231-H288 HydrophobicContact CZ-CB 4.33Å; F284-H288 PolarHBondContact O-CD2 3.36Å; F284-H288 PolarHBondContact O-N 3.2Å; L285-H288 PolarHBondContact O-N 3.21Å; H288-T292 VanDerWaalsContact O-CB 3.3Å; H288-T292 WeakPolarHBondContact O-CB 3.32Å; H288-T292 PolarHBondContact O-N 3.24Å; H288-T292 PolarHBondContact O-OG1 3Å
289	L	96.4	Very high	93.4	Very high	89 Å²	89	28.4 Å²	28.4	47%	0.466	16%	0.16	S	C	.	.	H	α-helix	trans	-60.2	-55.5	176.6	-179.2	62	0	0	0	110.8	L285 F287 T292 M293	L285-L289 VanDerWaalsContact O-CB 3.24Å; L285-L289 WeakPolarHBondContact O-CB 3.29Å; L285-L289 PolarHBondContact O-N 2.93Å; F287-L289 PolarHBondContact O-N 3.48Å; L289-T292 PolarHBondContact O-N 2.82Å; L289-M293 HydrophobicContact CD1-CE 3.7Å; L289-M293 HydrophobicContact CD1-SD 4.36Å; L289-M293 HydrophobicContact CD2-CE 4.44Å; L289-M293 HydrophobicContact CG-CE 3.97Å; L289-M293 HydrophobicContact CG-SD 4.15Å; L289-M293 WeakPolarHBondContact O-CG 3.19Å; L289-M293 PolarHBondContact O-N 2.94Å
290	T	96.6	Very high	93.5	Very high	11 Å²	11	31.9 Å²	31.9	7%	0.067	18%	0.178	C	C	.	.	H	α-helix	trans	-71.8	-34	-175	57.2	0	0	0	0	113	P286 F287 T292 Y294 I314 T318	P286-T290 WeakPolarHBondContact O-CB 3.4Å; P286-T290 VanDerWaalsContact O-CG2 3.24Å; P286-T290 WeakPolarHBondContact O-CG2 3.33Å; P286-T290 PolarHBondContact O-N 3.09Å; P286-T290 VanDerWaalsContact O-N 3.12Å; P286-T290 PolarHBondContact O-OG1 2.89Å; F287-T290 PolarHBondContact O-N 2.82Å; F287-T290 PolarHBondContact O-OG1 3.3Å; T290-T292 VanDerWaalsContact C-N 3.33Å; T290-Y294 VanDerWaalsContact O-CB 3.31Å; T290-Y294 WeakPolarHBondContact O-CB 3.07Å; T290-Y294 PolarHBondContact O-N 2.9Å; T290-I314 HydrophobicContact CG2-CG2 3.37Å; T290-T318 HydrophobicContact CG2-CG2 3.8Å; T290-T318 PolarHBondContact OG1-OG1 3.36Å
291	K	96.4	Very high	93.3	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-58.2	-48	169.1	-171.8	-162.3	73.2	148.5	0	110.1	L210 G223 T227 F287 Y294 L295 Y315	L210-K291 HydrophobicContact CD2-CD 4.36Å; L210-K291 HydrophobicContact CD2-CG 4.41Å; G223-K291 PolarHBondContact O-NZ 3.24Å; T227-K291 WeakPolarHBondContact OG1-CE 3.41Å; T227-K291 PolarHBondContact OG1-NZ 3.22Å; F287-K291 HydrophobicContact CE1-CD 4.12Å; F287-K291 HydrophobicContact CZ-CB 4.45Å; F287-K291 HydrophobicContact CZ-CD 4Å; F287-K291 HydrophobicContact CZ-CG 4.44Å; F287-K291 WeakPolarHBondContact O-CB 3.3Å; F287-K291 PolarHBondContact O-N 3.44Å; K291-Y294 PolarHBondContact O-N 3.33Å; K291-L295 HydrophobicContact CG-CD1 4.41Å; K291-L295 HydrophobicContact CG-CG 4.42Å; K291-L295 WeakPolarHBondContact O-CB 3.24Å; K291-L295 VanDerWaalsContact O-CG 3.28Å; K291-L295 WeakPolarHBondContact O-CG 3.32Å; K291-L295 PolarHBondContact O-N 3.4Å; K291-Y315 HydrophobicContact CB-CD2 3.92Å; K291-Y315 HydrophobicContact CB-CE2 3.86Å; K291-Y315 HydrophobicContact CG-CD2 4.31Å; K291-Y315 HydrophobicContact CG-CE2 3.86Å
292	T	96.7	Very high	93.3	Very high	31 Å²	31	39.4 Å²	39.4	19%	0.19	23%	0.228	C	C	.	.	H	α-helix	trans	-63.7	-46.7	-177.8	-58.2	0	0	0	0	111.2	M224 T227 H288 L289 T290 Y294 L295 V296	M224-T292 HydrophobicContact CE-CG2 3.81Å; M224-T292 HydrophobicContact SD-CG2 3.85Å; T227-T292 PolarHBondContact OG1-OG1 2.82Å; H288-T292 VanDerWaalsContact O-CB 3.3Å; H288-T292 WeakPolarHBondContact O-CB 3.32Å; H288-T292 PolarHBondContact O-N 3.24Å; H288-T292 PolarHBondContact O-OG1 3Å; L289-T292 PolarHBondContact O-N 2.82Å; T290-T292 VanDerWaalsContact C-N 3.33Å; T292-Y294 VanDerWaalsContact C-N 3.34Å; T292-Y294 PolarHBondContact O-N 3.26Å; T292-L295 PolarHBondContact O-N 2.96Å; T292-L295 VanDerWaalsContact O-N 3.16Å; T292-V296 WeakPolarHBondContact O-CG2 3.46Å; T292-V296 PolarHBondContact O-N 3.41Å
293	M	95.9	Very high	93.3	Very high	81 Å²	81	36.8 Å²	36.8	40%	0.399	21%	0.214	S	C	.	.	H	α-helix	trans	-58	-46	174.4	-69	171.1	165.1	0	0	111.8	L289 L295 V296 V297 F311	L289-M293 HydrophobicContact CD1-CE 3.7Å; L289-M293 HydrophobicContact CD1-SD 4.36Å; L289-M293 HydrophobicContact CD2-CE 4.44Å; L289-M293 HydrophobicContact CG-CE 3.97Å; L289-M293 HydrophobicContact CG-SD 4.15Å; L289-M293 WeakPolarHBondContact O-CG 3.19Å; L289-M293 PolarHBondContact O-N 2.94Å; M293-L295 VanDerWaalsContact C-N 3.33Å; M293-L295 PolarHBondContact O-N 3.23Å; M293-V296 PolarHBondContact O-N 3.06Å; M293-V297 WeakPolarHBondContact O-CG2 3.38Å; M293-V297 PolarHBondContact O-N 2.93Å; M293-F311 HydrophobicContact CB-CD1 3.62Å; M293-F311 HydrophobicContact CB-CE1 3.66Å; M293-F311 HydrophobicContact CG-CE1 4.16Å; M293-F311 HydrophobicContact SD-CE1 3.92Å
294	Y	95.7	Very high	93.3	Very high	27 Å²	27	40.7 Å²	40.7	11%	0.106	24%	0.239	C	C	.	.	H	α-helix	trans	-63.4	-37.4	176.7	178.8	-117.7	0	0	0	112.6	L210 T290 K291 T292 V297 R298 F311 A312 Y315	L210-Y294 HydrophobicContact CD1-CD1 3.87Å; L210-Y294 HydrophobicContact CD1-CE1 3.79Å; T290-Y294 VanDerWaalsContact O-CB 3.31Å; T290-Y294 WeakPolarHBondContact O-CB 3.07Å; T290-Y294 PolarHBondContact O-N 2.9Å; K291-Y294 PolarHBondContact O-N 3.33Å; T292-Y294 VanDerWaalsContact C-N 3.34Å; T292-Y294 PolarHBondContact O-N 3.26Å; Y294-V297 PolarHBondContact O-N 3.37Å; Y294-R298 HydrophobicContact CE2-CB 4.34Å; Y294-R298 VanDerWaalsContact O-CB 3.27Å; Y294-R298 WeakPolarHBondContact O-CB 3.41Å; Y294-R298 VanDerWaalsContact O-CG 3.27Å; Y294-R298 WeakPolarHBondContact O-CG 3.24Å; Y294-R298 PolarHBondContact O-N 2.84Å; Y294-F311 HydrophobicContact CD2-CB 4.21Å; Y294-A312 HydrophobicContact CD2-CB 4.15Å; Y294-A312 HydrophobicContact CE2-CB 3.62Å; Y294-Y315 AromaticContact CD1-CD1 3.78Å; Y294-Y315 HydrophobicContact CD1-CD1 3.78Å; Y294-Y315 HydrophobicContact CD1-CE1 4.26Å; Y294-Y315 HydrophobicContact CD1-CG 4.09Å; Y294-Y315 HydrophobicContact CE1-CD1 4.14Å; Y294-Y315 HydrophobicContact CE1-CE1 4.41Å; Y294-Y315 HydrophobicContact CG-CD1 4.32Å; Y294-Y315 HydrophobicContact CG-CG 4.31Å
295	L	95.4	Very high	93.2	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-64.5	-38.4	175.7	-73.5	-174.6	0	0	0	112.9	L210 Y219 Y220 K291 T292 M293 R298 T299	L210-L295 HydrophobicContact CD1-CD2 3.85Å; Y219-L295 HydrophobicContact CD1-CD2 3.81Å; Y219-L295 HydrophobicContact CE1-CD1 4.09Å; Y219-L295 HydrophobicContact CE1-CD2 3.73Å; Y220-L295 HydrophobicContact CD2-CB 4.14Å; Y220-L295 WeakPolarHBondContact CD2-O 3.29Å; Y220-L295 HydrophobicContact CE2-CB 4.39Å; K291-L295 HydrophobicContact CG-CD1 4.41Å; K291-L295 HydrophobicContact CG-CG 4.42Å; K291-L295 WeakPolarHBondContact O-CB 3.24Å; K291-L295 VanDerWaalsContact O-CG 3.28Å; K291-L295 WeakPolarHBondContact O-CG 3.32Å; K291-L295 PolarHBondContact O-N 3.4Å; T292-L295 PolarHBondContact O-N 2.96Å; T292-L295 VanDerWaalsContact O-N 3.16Å; M293-L295 VanDerWaalsContact C-N 3.33Å; M293-L295 PolarHBondContact O-N 3.23Å; L295-R298 VanDerWaalsContact O-CG 3.32Å; L295-R298 WeakPolarHBondContact O-CG 3.32Å; L295-T299 PolarHBondContact O-OG1 3.07Å; L295-T299 VanDerWaalsContact O-OG1 3.07Å
296	V	94.6	Very high	93.1	Very high	53 Å²	53	47.1 Å²	47.1	32%	0.321	27%	0.271	S	S	.	.	H	α-helix	trans	-67.4	-50.6	174.4	173.7	0	0	0	0	110.1	Y220 T292 M293 R298 T299 L300	Y220-V296 HydrophobicContact CE2-CG2 4.03Å; T292-V296 WeakPolarHBondContact O-CG2 3.46Å; T292-V296 PolarHBondContact O-N 3.41Å; M293-V296 PolarHBondContact O-N 3.06Å; V296-R298 VanDerWaalsContact C-N 3.34Å; V296-R298 PolarHBondContact O-N 3.44Å; V296-T299 PolarHBondContact O-N 3.35Å; V296-T299 PolarHBondContact O-OG1 3.49Å; V296-T299 VanDerWaalsContact O-OG1 3.05Å; V296-L300 HydrophobicContact CG1-CD1 3.96Å; V296-L300 HydrophobicContact CG1-CG 4.43Å; V296-L300 WeakPolarHBondContact O-CG 3.14Å; V296-L300 PolarHBondContact O-N 3.41Å
297	V	93.7	Very high	93	Very high	6 Å²	6	49 Å²	49	4%	0.036	28%	0.278	C	S	.	.	H	α-helix	trans	-67.1	-33	-176.1	174.3	0	0	0	0	112.6	M293 Y294 T299 A303 M307 R308 F311	M293-V297 WeakPolarHBondContact O-CG2 3.38Å; M293-V297 PolarHBondContact O-N 2.93Å; Y294-V297 PolarHBondContact O-N 3.37Å; V297-T299 VanDerWaalsContact C-N 3.32Å; V297-T299 PolarHBondContact O-N 2.91Å; V297-A303 HydrophobicContact CG1-CB 4.25Å; V297-M307 HydrophobicContact CG1-CG 4.01Å; V297-M307 HydrophobicContact CG1-SD 4.21Å; V297-M307 HydrophobicContact CG2-CE 3.71Å; V297-M307 HydrophobicContact CG2-SD 4.37Å; V297-R308 HydrophobicContact CG1-CB 4.42Å; V297-R308 HydrophobicContact CG1-CG 3.89Å; V297-R308 PolarHBondContact O-NH1 2.85Å; V297-F311 HydrophobicContact CB-CB 4.49Å; V297-F311 HydrophobicContact CB-CD2 4.28Å; V297-F311 HydrophobicContact CB-CG 4.44Å; V297-F311 HydrophobicContact CG1-CD2 4.12Å; V297-F311 HydrophobicContact CG2-CD2 3.71Å; V297-F311 HydrophobicContact CG2-CE2 3.96Å; V297-F311 HydrophobicContact CG2-CG 4.05Å; V297-F311 HydrophobicContact CG2-CZ 4.49Å
298	R	90.3	Very high	92.8	Very high	24 Å²	24	50.8 Å²	50.8	9%	0.091	29%	0.285	C	S	.	.	H	α-helix	trans	-70.4	-25.7	177.6	76.4	-174	-74.4	-149.1	-5.2	112.9	S211 S216 Y294 L295 V296 R308	S211-R298 PolarHBondContact OG-NH2 3.21Å; S216-R298 VanDerWaalsContact CB-NH2 3.27Å; Y294-R298 HydrophobicContact CE2-CB 4.34Å; Y294-R298 VanDerWaalsContact O-CB 3.27Å; Y294-R298 WeakPolarHBondContact O-CB 3.41Å; Y294-R298 VanDerWaalsContact O-CG 3.27Å; Y294-R298 WeakPolarHBondContact O-CG 3.24Å; Y294-R298 PolarHBondContact O-N 2.84Å; L295-R298 VanDerWaalsContact O-CG 3.32Å; L295-R298 WeakPolarHBondContact O-CG 3.32Å; V296-R298 VanDerWaalsContact C-N 3.34Å; V296-R298 PolarHBondContact O-N 3.44Å; R298-R308 VanDerWaalsContact C-NH1 3.32Å; R298-R308 PolarHBondContact O-NH1 2.85Å
299	T	90.7	Very high	92.6	Very high	32 Å²	32	52 Å²	52	20%	0.196	29%	0.291	C	S	.	.	H	α-helix	trans	-95.1	-20.8	-178.7	52.4	0	0	0	0	114.1	V217 Y220 L295 V296 V297 P301	V217-T299 HydrophobicContact CG2-CG2 4.48Å; Y220-T299 HydrophobicContact CD2-CG2 3.94Å; Y220-T299 HydrophobicContact CG-CG2 4.09Å; L295-T299 PolarHBondContact O-OG1 3.07Å; L295-T299 VanDerWaalsContact O-OG1 3.07Å; V296-T299 PolarHBondContact O-N 3.35Å; V296-T299 PolarHBondContact O-OG1 3.49Å; V296-T299 VanDerWaalsContact O-OG1 3.05Å; V297-T299 VanDerWaalsContact C-N 3.32Å; V297-T299 PolarHBondContact O-N 2.91Å; T299-P301 VanDerWaalsContact O-CD 3.26Å; T299-P301 WeakPolarHBondContact O-CD 2.98Å
300	L	90.1	Very high	92.5	Very high	74 Å²	74	52.2 Å²	52.2	39%	0.387	29%	0.292	S	S	.	.			trans	-64.8	117	174.1	-74.7	170.3	0	0	0	110.8	V296 S302 A303 R308	V296-L300 HydrophobicContact CG1-CD1 3.96Å; V296-L300 HydrophobicContact CG1-CG 4.43Å; V296-L300 WeakPolarHBondContact O-CG 3.14Å; V296-L300 PolarHBondContact O-N 3.41Å; L300-S302 PolarHBondContact O-N 3.07Å; L300-A303 HydrophobicContact CB-CB 4.01Å; L300-A303 PolarHBondContact O-N 3.48Å; L300-R308 VanDerWaalsContact O-CZ 3.3Å; L300-R308 PolarHBondContact O-NH1 2.65Å; L300-R308 PolarHBondContact O-NH2 3.19Å
301	P	84.6	Confident	92.5	Very high	120 Å²	120	53.7 Å²	53.7	78%	0.779	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.4	-40.6	-176.6	-24.8	35.7	0	0	0	113.5	T299 A303 R308	T299-P301 VanDerWaalsContact O-CD 3.26Å; T299-P301 WeakPolarHBondContact O-CD 2.98Å; P301-A303 VanDerWaalsContact C-N 3.33Å; P301-A303 PolarHBondContact O-N 3.2Å; P301-R308 PolarHBondContact O-NH2 2.72Å
302	S	87.6	Confident	92.3	Very high	110 Å²	110	53.7 Å²	53.7	77%	0.769	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.4	0.8	-175.6	48.6	0	0	0	0	115	L300 P304	L300-S302 PolarHBondContact O-N 3.07Å; S302-P304 WeakPolarHBondContact O-CD 3.17Å
303	A	88.7	Confident	92.2	Very high	13 Å²	13	54.3 Å²	54.3	11%	0.107	30%	0.3	C	S	.	.			trans	-67.7	126	-178.5	0	0	0	0	0	111.8	V297 L300 P301 M307 R308	V297-A303 HydrophobicContact CG1-CB 4.25Å; L300-A303 HydrophobicContact CB-CB 4.01Å; L300-A303 PolarHBondContact O-N 3.48Å; P301-A303 VanDerWaalsContact C-N 3.33Å; P301-A303 PolarHBondContact O-N 3.2Å; A303-M307 HydrophobicContact CB-SD 4.39Å; A303-R308 HydrophobicContact CB-CG 4.22Å; A303-R308 PolarHBondContact O-NE 3.01Å
304	P	91.8	Very high	92.1	Very high	81 Å²	81	53.4 Å²	53.4	53%	0.526	30%	0.296	S	S	.	.			trans	-57.9	148.2	177.6	-24.6	33.5	0	0	0	112.8	S302 E306 M307 R308	S302-P304 WeakPolarHBondContact O-CD 3.17Å; P304-E306 PolarHBondContact O-N 3.22Å; P304-M307 HydrophobicContact CB-CB 4.48Å; P304-M307 WeakPolarHBondContact O-CB 3.45Å; P304-M307 PolarHBondContact O-N 3.28Å; P304-M307 VanDerWaalsContact O-N 3.15Å; P304-R308 PolarHBondContact O-N 2.95Å
305	C	90.8	Very high	92.1	Very high	38 Å²	38	52.2 Å²	52.2	26%	0.257	29%	0.291	S	S	.	.	H	α-helix	trans	-59.3	-34.9	178.8	-72	0	0	0	0	112.8	C48 R308 N309	C48-C305 WeakPolarHBondContact CA-SG 3.47Å; C48-C305 HydrophobicContact CB-CB 3.76Å; C48-C305 WeakPolarHBondContact CB-SG 3.43Å; C48-C305 VanDerWaalsContact SG-CA 3.52Å; C48-C305 WeakPolarHBondContact SG-CB 3.42Å; C48-C305 CovalentContact SG-SG 2.04Å; C48-C305 PolarHBondContact SG-SG 3.26Å; C305-R308 PolarHBondContact O-N 3.33Å; C305-N309 VanDerWaalsContact O-CB 3.29Å; C305-N309 WeakPolarHBondContact O-CB 3.4Å; C305-N309 PolarHBondContact O-N 3.17Å
306	E	91.7	Very high	92.1	Very high	164 Å²	164	53.2 Å²	53.2	77%	0.766	30%	0.295	S	S	*	.	H	α-helix	trans	-61.5	-46	176.8	-174.8	175.6	-171.1	0	0	111.6	P304 N309 L310	P304-E306 PolarHBondContact O-N 3.22Å; E306-N309 PolarHBondContact O-N 2.88Å; E306-L310 WeakPolarHBondContact O-CB 3.25Å; E306-L310 PolarHBondContact O-N 3.4Å
307	M	93.1	Very high	92	Very high	74 Å²	74	52.5 Å²	52.5	37%	0.365	29%	0.293	S	S	.	.	H	α-helix	trans	-60.2	-49.1	175.3	-170.9	-171.9	-171.1	0	0	110.7	V297 A303 P304 N309 L310 F311	V297-M307 HydrophobicContact CG1-CG 4.01Å; V297-M307 HydrophobicContact CG1-SD 4.21Å; V297-M307 HydrophobicContact CG2-CE 3.71Å; V297-M307 HydrophobicContact CG2-SD 4.37Å; A303-M307 HydrophobicContact CB-SD 4.39Å; P304-M307 HydrophobicContact CB-CB 4.48Å; P304-M307 WeakPolarHBondContact O-CB 3.45Å; P304-M307 PolarHBondContact O-N 3.28Å; P304-M307 VanDerWaalsContact O-N 3.15Å; M307-N309 VanDerWaalsContact C-N 3.29Å; M307-N309 PolarHBondContact O-N 2.9Å; M307-L310 PolarHBondContact O-N 2.85Å; M307-F311 HydrophobicContact CE-CD2 4.35Å; M307-F311 HydrophobicContact CE-CE2 3.64Å; M307-F311 HydrophobicContact CE-CZ 4.39Å; M307-F311 HydrophobicContact CG-CD2 3.79Å; M307-F311 HydrophobicContact CG-CE2 3.72Å; M307-F311 VanDerWaalsContact O-CD2 3.28Å; M307-F311 WeakPolarHBondContact O-CD2 3.47Å; M307-F311 PolarHBondContact O-N 3.02Å
308	R	92.3	Very high	92.1	Very high	37 Å²	37	53 Å²	53	14%	0.14	30%	0.296	C	S	.	.	H	α-helix	trans	-58.3	-42.7	177.5	-65.9	175	-173.9	-91.3	20.7	112	Y50 V297 R298 L300 P301 A303 P304 C305 A312	Y50-R308 HydrophobicContact CE1-CB 4.22Å; V297-R308 HydrophobicContact CG1-CB 4.42Å; V297-R308 HydrophobicContact CG1-CG 3.89Å; V297-R308 PolarHBondContact O-NH1 2.85Å; R298-R308 VanDerWaalsContact C-NH1 3.32Å; R298-R308 PolarHBondContact O-NH1 2.85Å; L300-R308 VanDerWaalsContact O-CZ 3.3Å; L300-R308 PolarHBondContact O-NH1 2.65Å; L300-R308 PolarHBondContact O-NH2 3.19Å; P301-R308 PolarHBondContact O-NH2 2.72Å; A303-R308 HydrophobicContact CB-CG 4.22Å; A303-R308 PolarHBondContact O-NE 3.01Å; P304-R308 PolarHBondContact O-N 2.95Å; C305-R308 PolarHBondContact O-N 3.33Å; R308-A312 VanDerWaalsContact O-CB 3.25Å; R308-A312 WeakPolarHBondContact O-CB 3.49Å; R308-A312 PolarHBondContact O-N 2.66Å
309	N	92.8	Very high	92.2	Very high	28 Å²	28	52.1 Å²	52.1	15%	0.15	29%	0.293	C	S	.	.	H	α-helix	trans	-64.6	-45.8	177.5	-178.2	62.2	0	0	0	111.6	Y50 K51 C305 E306 M307 A312 I313	Y50-N309 VanDerWaalsContact CA-OD1 3.28Å; Y50-N309 WeakPolarHBondContact CA-OD1 3.23Å; Y50-N309 HydrophobicContact CD1-CB 4.27Å; K51-N309 PolarHBondContact N-OD1 2.95Å; C305-N309 VanDerWaalsContact O-CB 3.29Å; C305-N309 WeakPolarHBondContact O-CB 3.4Å; C305-N309 PolarHBondContact O-N 3.17Å; E306-N309 PolarHBondContact O-N 2.88Å; M307-N309 VanDerWaalsContact C-N 3.29Å; M307-N309 PolarHBondContact O-N 2.9Å; N309-A312 WeakPolarHBondContact O-CB 3.26Å; N309-A312 PolarHBondContact O-N 3.3Å; N309-I313 WeakPolarHBondContact ND2-CD1 3.29Å; N309-I313 VanDerWaalsContact O-CG1 3.26Å; N309-I313 WeakPolarHBondContact O-CG1 3.39Å; N309-I313 PolarHBondContact O-N 3Å
310	L	94.2	Very high	92.4	Very high	92 Å²	92	50.8 Å²	50.8	48%	0.482	29%	0.285	S	S	.	.	H	α-helix	trans	-57.7	-52.4	177.1	177.6	62.4	0	0	0	111.6	E306 M307 A312 I313 I314	E306-L310 WeakPolarHBondContact O-CB 3.25Å; E306-L310 PolarHBondContact O-N 3.4Å; M307-L310 PolarHBondContact O-N 2.85Å; L310-A312 VanDerWaalsContact C-N 3.29Å; L310-A312 PolarHBondContact O-N 3.19Å; L310-I313 PolarHBondContact O-N 3.43Å; L310-I314 HydrophobicContact CD1-CD1 3.87Å; L310-I314 HydrophobicContact CD1-CG1 4.28Å; L310-I314 HydrophobicContact CG-CD1 3.87Å; L310-I314 VanDerWaalsContact O-CG1 3.32Å; L310-I314 WeakPolarHBondContact O-CG1 3.49Å; L310-I314 PolarHBondContact O-N 2.94Å
311	F	94.6	Very high	92.5	Very high	42 Å²	42	51.1 Å²	51.1	18%	0.184	28%	0.283	C	S	.	.	H	α-helix	trans	-66.8	-31	179.7	-77.9	-79.5	0	0	0	112.6	M293 Y294 V297 M307 Y315	M293-F311 HydrophobicContact CB-CD1 3.62Å; M293-F311 HydrophobicContact CB-CE1 3.66Å; M293-F311 HydrophobicContact CG-CE1 4.16Å; M293-F311 HydrophobicContact SD-CE1 3.92Å; Y294-F311 HydrophobicContact CD2-CB 4.21Å; V297-F311 HydrophobicContact CB-CB 4.49Å; V297-F311 HydrophobicContact CB-CD2 4.28Å; V297-F311 HydrophobicContact CB-CG 4.44Å; V297-F311 HydrophobicContact CG1-CD2 4.12Å; V297-F311 HydrophobicContact CG2-CD2 3.71Å; V297-F311 HydrophobicContact CG2-CE2 3.96Å; V297-F311 HydrophobicContact CG2-CG 4.05Å; V297-F311 HydrophobicContact CG2-CZ 4.49Å; M307-F311 HydrophobicContact CE-CD2 4.35Å; M307-F311 HydrophobicContact CE-CE2 3.64Å; M307-F311 HydrophobicContact CE-CZ 4.39Å; M307-F311 HydrophobicContact CG-CD2 3.79Å; M307-F311 HydrophobicContact CG-CE2 3.72Å; M307-F311 VanDerWaalsContact O-CD2 3.28Å; M307-F311 WeakPolarHBondContact O-CD2 3.47Å; M307-F311 PolarHBondContact O-N 3.02Å; F311-Y315 WeakPolarHBondContact O-CB 3.27Å; F311-Y315 PolarHBondContact O-N 3.31Å
312	A	93.1	Very high	93	Very high	0 Å²	0	45.5 Å²	45.5	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-65.4	-44.4	172	0	0	0	0	0	112	Y50 Y294 R308 N309 L310 K316	Y50-A312 HydrophobicContact CD1-CB 3.66Å; Y50-A312 HydrophobicContact CE1-CB 3.7Å; Y294-A312 HydrophobicContact CD2-CB 4.15Å; Y294-A312 HydrophobicContact CE2-CB 3.62Å; R308-A312 VanDerWaalsContact O-CB 3.25Å; R308-A312 WeakPolarHBondContact O-CB 3.49Å; R308-A312 PolarHBondContact O-N 2.66Å; N309-A312 WeakPolarHBondContact O-CB 3.26Å; N309-A312 PolarHBondContact O-N 3.3Å; L310-A312 VanDerWaalsContact C-N 3.29Å; L310-A312 PolarHBondContact O-N 3.19Å; A312-K316 WeakPolarHBondContact O-CB 3.25Å; A312-K316 VanDerWaalsContact O-CG 3.31Å; A312-K316 WeakPolarHBondContact O-CG 3.24Å; A312-K316 PolarHBondContact O-N 2.84Å
313	I	94.3	Very high	93.3	Very high	45 Å²	45	40.2 Å²	40.2	23%	0.231	21%	0.21	C	C	.	.	H	α-helix	trans	-60.8	-49.7	176.2	-70.1	166.5	0	0	0	110	F54 N309 L310 K316 S317	F54-I313 HydrophobicContact CE1-CB 4.21Å; F54-I313 HydrophobicContact CE1-CG1 4.01Å; F54-I313 HydrophobicContact CE1-CG2 3.82Å; F54-I313 HydrophobicContact CZ-CB 4.47Å; F54-I313 HydrophobicContact CZ-CG2 4.01Å; N309-I313 WeakPolarHBondContact ND2-CD1 3.29Å; N309-I313 VanDerWaalsContact O-CG1 3.26Å; N309-I313 WeakPolarHBondContact O-CG1 3.39Å; N309-I313 PolarHBondContact O-N 3Å; L310-I313 PolarHBondContact O-N 3.43Å; I313-K316 PolarHBondContact O-N 3.28Å; I313-S317 VanDerWaalsContact O-CB 3.31Å; I313-S317 WeakPolarHBondContact O-CB 3.42Å; I313-S317 PolarHBondContact O-N 3.19Å; I313-S317 PolarHBondContact O-OG 3.12Å
314	I	95.1	Very high	93.5	Very high	62 Å²	62	41.3 Å²	41.3	32%	0.318	21%	0.213	S	C	.	.	H	α-helix	trans	-59.9	-50.2	-179.9	-68.1	169.1	0	0	0	110.3	T290 L310 K316 S317 T318	T290-I314 HydrophobicContact CG2-CG2 3.37Å; L310-I314 HydrophobicContact CD1-CD1 3.87Å; L310-I314 HydrophobicContact CD1-CG1 4.28Å; L310-I314 HydrophobicContact CG-CD1 3.87Å; L310-I314 VanDerWaalsContact O-CG1 3.32Å; L310-I314 WeakPolarHBondContact O-CG1 3.49Å; L310-I314 PolarHBondContact O-N 2.94Å; I314-K316 VanDerWaalsContact C-N 3.35Å; I314-K316 PolarHBondContact O-N 2.63Å; I314-S317 PolarHBondContact O-N 3.49Å; I314-T318 WeakPolarHBondContact O-CG2 3.26Å; I314-T318 PolarHBondContact O-N 3.47Å; I314-T318 PolarHBondContact O-OG1 2.68Å
315	Y	95.1	Very high	93.6	Very high	2 Å²	2	37.5 Å²	37.5	1%	0.008	19%	0.188	C	C	.	.	H	α-helix	trans	-57.3	-45	177.2	162	-111	0	0	0	112.7	L210 F287 K291 Y294 F311 S317 T318 R319	L210-Y315 HydrophobicContact CD1-CE1 4.29Å; F287-Y315 HydrophobicContact CD2-CE2 4.3Å; F287-Y315 HydrophobicContact CE2-CD2 4.48Å; F287-Y315 AromaticContact CE2-CE2 3.65Å; F287-Y315 HydrophobicContact CE2-CE2 3.65Å; F287-Y315 HydrophobicContact CZ-CE2 4.31Å; K291-Y315 HydrophobicContact CB-CD2 3.92Å; K291-Y315 HydrophobicContact CB-CE2 3.86Å; K291-Y315 HydrophobicContact CG-CD2 4.31Å; K291-Y315 HydrophobicContact CG-CE2 3.86Å; Y294-Y315 AromaticContact CD1-CD1 3.78Å; Y294-Y315 HydrophobicContact CD1-CD1 3.78Å; Y294-Y315 HydrophobicContact CD1-CE1 4.26Å; Y294-Y315 HydrophobicContact CD1-CG 4.09Å; Y294-Y315 HydrophobicContact CE1-CD1 4.14Å; Y294-Y315 HydrophobicContact CE1-CE1 4.41Å; Y294-Y315 HydrophobicContact CG-CD1 4.32Å; Y294-Y315 HydrophobicContact CG-CG 4.31Å; F311-Y315 WeakPolarHBondContact O-CB 3.27Å; F311-Y315 PolarHBondContact O-N 3.31Å; Y315-S317 VanDerWaalsContact C-N 3.33Å; Y315-T318 PolarHBondContact O-N 2.96Å; Y315-T318 PolarHBondContact O-OG1 3.48Å; Y315-R319 PolarHBondContact O-N 3.05Å
316	K	94.4	Very high	93.7	Very high	20 Å²	20	35.7 Å²	35.7	9%	0.087	18%	0.176	C	C	.	.	H	α-helix	trans	-69.5	-32.5	179.1	-73.7	-173.4	174.6	91.3	0	112.4	E52 F54 K55 A312 I313 I314 P320	E52-K316 HydrophobicContact CG-CD 4.43Å; E52-K316 IonicContact OE1-NZ 2.62Å; E52-K316 PolarHBondContact OE1-NZ 2.81Å; E52-K316 WeakPolarHBondContact OE2-CD 3.27Å; E52-K316 WeakPolarHBondContact OE2-CE 3.41Å; E52-K316 IonicContact OE2-NZ 2.9Å; E52-K316 PolarHBondContact OE2-NZ 2.97Å; F54-K316 HydrophobicContact CZ-CB 3.96Å; K55-K316 HydrophobicContact CD-CD 4Å; A312-K316 WeakPolarHBondContact O-CB 3.25Å; A312-K316 VanDerWaalsContact O-CG 3.31Å; A312-K316 WeakPolarHBondContact O-CG 3.24Å; A312-K316 PolarHBondContact O-N 2.84Å; I313-K316 PolarHBondContact O-N 3.28Å; I314-K316 VanDerWaalsContact C-N 3.35Å; I314-K316 PolarHBondContact O-N 2.63Å; K316-P320 WeakPolarHBondContact O-CD 3.38Å
317	S	93.6	Very high	93.7	Very high	38 Å²	38	28.9 Å²	28.9	27%	0.266	14%	0.144	S	C	.	.	H	α-helix	trans	-71.9	-30.7	177.4	-57.8	0	0	0	0	112.5	F54 I313 I314 Y315 P320	F54-S317 VanDerWaalsContact CE2-OG 3.23Å; F54-S317 WeakPolarHBondContact CE2-OG 3.39Å; F54-S317 WeakPolarHBondContact CZ-OG 3.3Å; I313-S317 VanDerWaalsContact O-CB 3.31Å; I313-S317 WeakPolarHBondContact O-CB 3.42Å; I313-S317 PolarHBondContact O-N 3.19Å; I313-S317 PolarHBondContact O-OG 3.12Å; I314-S317 PolarHBondContact O-N 3.49Å; Y315-S317 VanDerWaalsContact C-N 3.33Å; S317-P320 WeakPolarHBondContact O-CD 3.35Å
318	T	94.5	Very high	93.5	Very high	18 Å²	18	27.2 Å²	27.2	11%	0.11	14%	0.136	C	C	.	.	H	α-helix	trans	-87.6	-20.3	179.8	55.2	0	0	0	0	114	P286 T290 I314 Y315 F321	P286-T318 HydrophobicContact CB-CG2 4.12Å; T290-T318 HydrophobicContact CG2-CG2 3.8Å; T290-T318 PolarHBondContact OG1-OG1 3.36Å; I314-T318 WeakPolarHBondContact O-CG2 3.26Å; I314-T318 PolarHBondContact O-N 3.47Å; I314-T318 PolarHBondContact O-OG1 2.68Å; Y315-T318 PolarHBondContact O-N 2.96Å; Y315-T318 PolarHBondContact O-OG1 3.48Å; T318-F321 HydrophobicContact CG2-CD2 4.41Å; T318-F321 WeakPolarHBondContact O-CB 3.34Å; T318-F321 VanDerWaalsContact O-CD2 3.3Å; T318-F321 WeakPolarHBondContact O-CD2 3.5Å; T318-F321 PolarHBondContact O-N 2.92Å
319	R	93.9	Very high	93.2	Very high	4 Å²	4	25.5 Å²	25.5	2%	0.015	13%	0.13	C	C	.	.	H	α-helix	trans	-55	-38.9	179.8	-173	169.9	173.5	-144.5	-17	115.4	Y116 R133 F136 D209 F287 Y315 F321 A322	Y116-R319 PolarHBondContact OH-NH1 2.87Å; R133-R319 VanDerWaalsContact NH1-CZ 3.3Å; F136-R319 HydrophobicContact CE2-CG 4.28Å; F136-R319 HydrophobicContact CZ-CG 4.04Å; D209-R319 IonicContact OD1-CZ 2.65Å; D209-R319 IonicContact OD1-NH1 2.88Å; D209-R319 PolarHBondContact OD1-NH1 2.91Å; D209-R319 IonicContact OD2-NH1 2.73Å; D209-R319 PolarHBondContact OD2-NH1 2.87Å; F287-R319 HydrophobicContact CD2-CB 4.27Å; F287-R319 HydrophobicContact CD2-CG 4.29Å; F287-R319 HydrophobicContact CE2-CB 4.39Å; F287-R319 HydrophobicContact CE2-CG 4.06Å; Y315-R319 PolarHBondContact O-N 3.05Å; R319-F321 PolarHBondContact O-N 3.35Å; R319-A322 WeakPolarHBondContact O-CB 3.45Å; R319-A322 PolarHBondContact O-N 3.12Å
320	P	93.9	Very high	92.7	Very high	5 Å²	5	24.8 Å²	24.8	3%	0.032	13%	0.127	C	C	.	.	H	α-helix	trans	-59	-30.8	174.1	-17.6	26.1	0	0	0	113.6	L58 L59 V62 K316 S317 A322 S323 M324	L58-P320 HydrophobicContact CG-CG 4.46Å; L59-P320 HydrophobicContact CD2-CG 3.77Å; V62-P320 HydrophobicContact CB-CB 3.87Å; V62-P320 HydrophobicContact CG1-CB 3.57Å; V62-P320 HydrophobicContact CG2-CB 4.09Å; K316-P320 WeakPolarHBondContact O-CD 3.38Å; S317-P320 WeakPolarHBondContact O-CD 3.35Å; P320-A322 VanDerWaalsContact C-N 3.29Å; P320-A322 PolarHBondContact O-N 3.05Å; P320-S323 WeakPolarHBondContact O-CB 3.37Å; P320-S323 PolarHBondContact O-N 2.99Å; P320-S323 VanDerWaalsContact O-N 3.07Å; P320-M324 WeakPolarHBondContact O-CG 3.12Å; P320-M324 PolarHBondContact O-N 2.86Å; P320-M324 VanDerWaalsContact O-N 3.14Å
321	F	93.3	Very high	92.1	Very high	81 Å²	81	22.9 Å²	22.9	36%	0.355	12%	0.116	S	C	.	.	H	α-helix	trans	-61	-38.4	177.9	-63.7	-72.9	0	0	0	112.3	V282 S283 T318 R319 S323 M324	V282-F321 HydrophobicContact CG1-CD1 4.4Å; V282-F321 VanDerWaalsContact O-CB 3.27Å; V282-F321 WeakPolarHBondContact O-CB 3.44Å; S283-F321 VanDerWaalsContact CA-O 3.3Å; S283-F321 WeakPolarHBondContact CA-O 3.23Å; S283-F321 VanDerWaalsContact CB-O 3.27Å; S283-F321 WeakPolarHBondContact CB-O 3.31Å; S283-F321 CarbonylContact O-C 3.57Å; T318-F321 HydrophobicContact CG2-CD2 4.41Å; T318-F321 WeakPolarHBondContact O-CB 3.34Å; T318-F321 VanDerWaalsContact O-CD2 3.3Å; T318-F321 WeakPolarHBondContact O-CD2 3.5Å; T318-F321 PolarHBondContact O-N 2.92Å; R319-F321 PolarHBondContact O-N 3.35Å; F321-S323 VanDerWaalsContact C-N 3.27Å; F321-S323 PolarHBondContact O-N 3.4Å; F321-M324 HydrophobicContact CB-CE 4.15Å; F321-M324 HydrophobicContact CD1-CE 3.06Å; F321-M324 HydrophobicContact CE1-CE 3.63Å; F321-M324 HydrophobicContact CG-CE 3.91Å; F321-M324 PolarHBondContact O-N 3.35Å; F321-M324 VanDerWaalsContact O-N 3.16Å
322	A	94.5	Very high	91.1	Very high	1 Å²	1	22.9 Å²	22.9	1%	0.008	12%	0.118	C	C	.	.	H	α-helix	trans	-59.8	-39.8	174.8	0	0	0	0	0	111.8	F136 L140 S283 F287 R319 P320 M324 N325	F136-A322 HydrophobicContact CE2-CB 4.14Å; F136-A322 HydrophobicContact CZ-CB 4.04Å; L140-A322 HydrophobicContact CD1-CB 4.18Å; S283-A322 WeakPolarHBondContact O-CA 3.06Å; S283-A322 PolarHBondContact O-N 3.2Å; F287-A322 HydrophobicContact CB-CB 3.95Å; F287-A322 HydrophobicContact CD1-CB 4.39Å; F287-A322 HydrophobicContact CD2-CB 4.29Å; F287-A322 HydrophobicContact CG-CB 3.94Å; R319-A322 WeakPolarHBondContact O-CB 3.45Å; R319-A322 PolarHBondContact O-N 3.12Å; P320-A322 VanDerWaalsContact C-N 3.29Å; P320-A322 PolarHBondContact O-N 3.05Å; A322-M324 VanDerWaalsContact C-N 3.3Å; A322-M324 PolarHBondContact O-N 2.9Å; A322-N325 VanDerWaalsContact O-CG 3.32Å; A322-N325 PolarHBondContact O-N 3.14Å; A322-N325 PolarHBondContact O-OD1 2.9Å
323	S	94.4	Very high	90.2	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-70	-24.5	178.4	-52.6	0	0	0	0	113.6	Y63 V66 Y105 P320 F321 N325 S326	Y63-S323 VanDerWaalsContact CE1-OG 3.28Å; Y63-S323 WeakPolarHBondContact CE1-OG 3.35Å; V66-S323 VanDerWaalsContact CG1-O 3.28Å; V66-S323 WeakPolarHBondContact CG1-O 3.15Å; Y105-S323 WeakPolarHBondContact OH-CB 3.31Å; Y105-S323 PolarHBondContact OH-OG 3.47Å; P320-S323 WeakPolarHBondContact O-CB 3.37Å; P320-S323 PolarHBondContact O-N 2.99Å; P320-S323 VanDerWaalsContact O-N 3.07Å; F321-S323 VanDerWaalsContact C-N 3.27Å; F321-S323 PolarHBondContact O-N 3.4Å; S323-N325 PolarHBondContact O-N 2.86Å; S323-S326 PolarHBondContact O-N 3.19Å
324	M	93.1	Very high	89.1	Confident	36 Å²	36	25.2 Å²	25.2	18%	0.177	13%	0.125	C	C	.	.	H	α-helix	trans	-69.4	-17.7	179.9	-65.9	-161.5	-77.9	0	0	113.2	V62 V66 P320 F321 A322 S326 F327 L328	V62-M324 HydrophobicContact CG1-CG 4.18Å; V62-M324 HydrophobicContact CG1-SD 4.46Å; V66-M324 HydrophobicContact CG2-CG 4.25Å; P320-M324 WeakPolarHBondContact O-CG 3.12Å; P320-M324 PolarHBondContact O-N 2.86Å; P320-M324 VanDerWaalsContact O-N 3.14Å; F321-M324 HydrophobicContact CB-CE 4.15Å; F321-M324 HydrophobicContact CD1-CE 3.06Å; F321-M324 HydrophobicContact CE1-CE 3.63Å; F321-M324 HydrophobicContact CG-CE 3.91Å; F321-M324 PolarHBondContact O-N 3.35Å; F321-M324 VanDerWaalsContact O-N 3.16Å; A322-M324 VanDerWaalsContact C-N 3.3Å; A322-M324 PolarHBondContact O-N 2.9Å; M324-S326 PolarHBondContact O-N 3.26Å; M324-F327 HydrophobicContact CB-CD1 4.46Å; M324-F327 HydrophobicContact CB-CE1 3.67Å; M324-F327 HydrophobicContact CB-CZ 3.83Å; M324-F327 HydrophobicContact CG-CE1 3.64Å; M324-F327 HydrophobicContact CG-CZ 3.87Å; M324-F327 PolarHBondContact O-N 2.89Å; M324-F327 HydrophobicContact SD-CE1 4.22Å; M324-F327 HydrophobicContact SD-CZ 3.89Å; M324-L328 HydrophobicContact CB-CD1 3.85Å; M324-L328 HydrophobicContact CB-CG 4.34Å; M324-L328 WeakPolarHBondContact O-CB 3.48Å; M324-L328 VanDerWaalsContact O-CG 3.25Å; M324-L328 WeakPolarHBondContact O-CG 3.24Å; M324-L328 PolarHBondContact O-N 2.83Å
325	N	92.7	Very high	87.7	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-51.4	-34.4	174.1	79.7	-14.6	0	0	0	111.6	N139 S143 F284 A322 S323 F327 L328 D329	N139-N325 PolarHBondContact OD1-ND2 3.32Å; N139-N325 PolarHBondContact OD1-OD1 3.34Å; S143-N325 VanDerWaalsContact CB-ND2 3.32Å; S143-N325 WeakPolarHBondContact CB-ND2 3.22Å; S143-N325 PolarHBondContact OG-ND2 3.21Å; S143-N325 VanDerWaalsContact OG-ND2 3.1Å; F284-N325 HydrophobicContact CE1-CB 3.75Å; F284-N325 WeakPolarHBondContact CE1-ND2 3.37Å; F284-N325 HydrophobicContact CZ-CB 3.89Å; A322-N325 VanDerWaalsContact O-CG 3.32Å; A322-N325 PolarHBondContact O-N 3.14Å; A322-N325 PolarHBondContact O-OD1 2.9Å; S323-N325 PolarHBondContact O-N 2.86Å; N325-F327 PolarHBondContact O-N 3.21Å; N325-F327 VanDerWaalsContact O-N 3.12Å; N325-L328 PolarHBondContact O-N 3.26Å; N325-D329 WeakPolarHBondContact O-CB 3.45Å; N325-D329 PolarHBondContact O-N 2.92Å
326	S	93.9	Very high	86	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-71.7	-16.3	-168.3	-59.3	0	0	0	0	112.4	N74 D102 Y105 S323 M324	N74-S326 PolarHBondContact ND2-O 2.9Å; D102-S326 PolarHBondContact OD1-OG 2.62Å; Y105-S326 WeakPolarHBondContact CD1-OG 3.37Å; S323-S326 PolarHBondContact O-N 3.19Å; M324-S326 PolarHBondContact O-N 3.26Å
327	F	91.6	Very high	84.5	Confident	22 Å²	22	28.2 Å²	28.2	10%	0.096	14%	0.138	C	C	.	.	H	α-helix	trans	-114.5	-28.3	169.3	71.9	-103.4	0	0	0	112.7	V66 L69 L73 M324 N325 I331	V66-F327 HydrophobicContact CB-CD1 4.29Å; V66-F327 HydrophobicContact CG1-CD1 4.39Å; V66-F327 HydrophobicContact CG2-CD1 3.91Å; V66-F327 HydrophobicContact CG2-CE1 3.73Å; L69-F327 HydrophobicContact CB-CB 3.91Å; L69-F327 HydrophobicContact CB-CG 4.25Å; L69-F327 HydrophobicContact CD1-CD2 4.22Å; L69-F327 HydrophobicContact CD1-CE2 4.49Å; L69-F327 HydrophobicContact CD1-CG 4.34Å; L73-F327 HydrophobicContact CD1-CB 3.84Å; M324-F327 HydrophobicContact CB-CD1 4.46Å; M324-F327 HydrophobicContact CB-CE1 3.67Å; M324-F327 HydrophobicContact CB-CZ 3.83Å; M324-F327 HydrophobicContact CG-CE1 3.64Å; M324-F327 HydrophobicContact CG-CZ 3.87Å; M324-F327 PolarHBondContact O-N 2.89Å; M324-F327 HydrophobicContact SD-CE1 4.22Å; M324-F327 HydrophobicContact SD-CZ 3.89Å; N325-F327 PolarHBondContact O-N 3.21Å; N325-F327 VanDerWaalsContact O-N 3.12Å; F327-I331 HydrophobicContact CD2-CD1 3.98Å; F327-I331 WeakPolarHBondContact O-CD1 3.49Å; F327-I331 VanDerWaalsContact O-CG1 3.27Å; F327-I331 WeakPolarHBondContact O-CG1 3.49Å; F327-I331 PolarHBondContact O-N 2.92Å
328	L	88.4	Confident	82.8	Confident	38 Å²	38	28.7 Å²	28.7	20%	0.199	14%	0.14	C	C	.	.	H	α-helix	trans	-65.3	-40	178.1	-71.7	174.7	0	0	0	111.4	M324 N325 I331 L332	M324-L328 HydrophobicContact CB-CD1 3.85Å; M324-L328 HydrophobicContact CB-CG 4.34Å; M324-L328 WeakPolarHBondContact O-CB 3.48Å; M324-L328 VanDerWaalsContact O-CG 3.25Å; M324-L328 WeakPolarHBondContact O-CG 3.24Å; M324-L328 PolarHBondContact O-N 2.83Å; N325-L328 PolarHBondContact O-N 3.26Å; L328-I331 PolarHBondContact O-N 3.42Å; L328-L332 HydrophobicContact CB-CD1 4.25Å; L328-L332 VanDerWaalsContact O-CB 3.28Å; L328-L332 WeakPolarHBondContact O-CB 3.14Å; L328-L332 WeakPolarHBondContact O-CG 3.24Å; L328-L332 PolarHBondContact O-N 3.16Å
329	D	85.4	Confident	81	Confident	1 Å²	1	36.6 Å²	36.6	1%	0.005	17%	0.168	C	C	.	.	H	α-helix	trans	-59.5	-55.7	-178.2	-76.2	-4.6	0	0	0	111.6	L98 V279 N325 I331 L332 F333	L98-D329 HydrophobicContact CD2-CB 4.24Å; V279-D329 WeakPolarHBondContact CG1-OD1 3.3Å; V279-D329 VanDerWaalsContact CG2-OD1 3.28Å; V279-D329 WeakPolarHBondContact CG2-OD1 3.42Å; N325-D329 WeakPolarHBondContact O-CB 3.45Å; N325-D329 PolarHBondContact O-N 2.92Å; D329-I331 VanDerWaalsContact C-N 3.33Å; D329-I331 PolarHBondContact O-N 3.3Å; D329-L332 PolarHBondContact O-N 3.38Å; D329-F333 HydrophobicContact CB-CD2 4.31Å; D329-F333 HydrophobicContact CB-CE2 4.29Å; D329-F333 WeakPolarHBondContact O-CB 3.33Å; D329-F333 WeakPolarHBondContact O-CD2 3.07Å; D329-F333 PolarHBondContact O-N 2.98Å
330	P	83.4	Confident	79	Confident	14 Å²	14	37.8 Å²	37.8	9%	0.091	17%	0.173	C	C	.	.	H	α-helix	trans	-55.8	-41.9	174.8	-27.4	33.7	0	0	0	114.4	L73 N74 V77 Y334	L73-P330 HydrophobicContact CB-CB 3.95Å; L73-P330 HydrophobicContact CB-CG 4.15Å; N74-P330 WeakPolarHBondContact OD1-CG 3.37Å; V77-P330 HydrophobicContact CG2-CB 4.24Å; P330-Y334 VanDerWaalsContact O-CB 3.25Å; P330-Y334 WeakPolarHBondContact O-CB 3.26Å; P330-Y334 PolarHBondContact O-N 3.02Å
331	I	79.9	Confident	77.2	Confident	51 Å²	51	42.7 Å²	42.7	26%	0.262	19%	0.19	S	C	.	.	H	α-helix	trans	-62.9	-53.4	180	-73.1	176	0	0	0	109.9	L73 F327 L328 D329 F333 Y334 F335	L73-I331 HydrophobicContact CD1-CD1 4Å; L73-I331 HydrophobicContact CD1-CG1 3.86Å; L73-I331 HydrophobicContact CD2-CG1 4.4Å; F327-I331 HydrophobicContact CD2-CD1 3.98Å; F327-I331 WeakPolarHBondContact O-CD1 3.49Å; F327-I331 VanDerWaalsContact O-CG1 3.27Å; F327-I331 WeakPolarHBondContact O-CG1 3.49Å; F327-I331 PolarHBondContact O-N 2.92Å; L328-I331 PolarHBondContact O-N 3.42Å; D329-I331 VanDerWaalsContact C-N 3.33Å; D329-I331 PolarHBondContact O-N 3.3Å; I331-F333 PolarHBondContact O-N 2.98Å; I331-Y334 WeakPolarHBondContact O-CB 3.23Å; I331-Y334 PolarHBondContact O-N 3.2Å; I331-F335 HydrophobicContact CG2-CD2 3.73Å; I331-F335 HydrophobicContact CG2-CE2 3.77Å; I331-F335 WeakPolarHBondContact O-CD2 3.49Å; I331-F335 PolarHBondContact O-N 3.46Å
332	L	74.7	Confident	75.6	Confident	43 Å²	43	45.6 Å²	45.6	23%	0.225	20%	0.203	C	C	.	.	H	α-helix	trans	-65.4	-40.5	-177.5	-67	171.7	0	0	0	110.7	V275 V279 L328 D329 Y334 F335 T336	V275-L332 HydrophobicContact CB-CB 4.32Å; V275-L332 HydrophobicContact CG1-CB 3.54Å; V275-L332 HydrophobicContact CG1-CD1 4.15Å; V275-L332 HydrophobicContact CG1-CG 4.4Å; V275-L332 HydrophobicContact CG2-CB 3.84Å; V275-L332 HydrophobicContact CG2-CD2 4.22Å; V275-L332 HydrophobicContact CG2-CG 4.49Å; V279-L332 HydrophobicContact CG2-CD1 3.4Å; L328-L332 HydrophobicContact CB-CD1 4.25Å; L328-L332 VanDerWaalsContact O-CB 3.28Å; L328-L332 WeakPolarHBondContact O-CB 3.14Å; L328-L332 WeakPolarHBondContact O-CG 3.24Å; L328-L332 PolarHBondContact O-N 3.16Å; D329-L332 PolarHBondContact O-N 3.38Å; L332-Y334 PolarHBondContact O-N 3.15Å; L332-F335 PolarHBondContact O-N 3.37Å; L332-T336 VanDerWaalsContact O-CB 3.32Å; L332-T336 WeakPolarHBondContact O-CB 3.35Å; L332-T336 VanDerWaalsContact O-CG2 3.23Å; L332-T336 WeakPolarHBondContact O-CG2 3.42Å; L332-T336 PolarHBondContact O-N 2.84Å; L332-T336 PolarHBondContact O-OG1 3.43Å
333	F	73.1	Confident	73.8	Confident	15 Å²	15	48.1 Å²	48.1	7%	0.066	22%	0.22	C	C	.	.	H	α-helix	trans	-64.8	-36.6	173.7	-78.3	-58.6	0	0	0	113.2	M95 L98 L147 I150 D329 I331 T336 Q337	M95-F333 HydrophobicContact SD-CD1 4.32Å; M95-F333 HydrophobicContact SD-CG 4.37Å; L98-F333 HydrophobicContact CD2-CE2 3.81Å; L147-F333 HydrophobicContact CD2-CE2 3.81Å; L147-F333 HydrophobicContact CD2-CZ 3.6Å; I150-F333 HydrophobicContact CD1-CE1 4.49Å; I150-F333 HydrophobicContact CD1-CE2 4.44Å; I150-F333 HydrophobicContact CD1-CZ 3.86Å; I150-F333 HydrophobicContact CG2-CE1 4.28Å; I150-F333 HydrophobicContact CG2-CZ 4.44Å; D329-F333 HydrophobicContact CB-CD2 4.31Å; D329-F333 HydrophobicContact CB-CE2 4.29Å; D329-F333 WeakPolarHBondContact O-CB 3.33Å; D329-F333 WeakPolarHBondContact O-CD2 3.07Å; D329-F333 PolarHBondContact O-N 2.98Å; I331-F333 PolarHBondContact O-N 2.98Å; F333-T336 PolarHBondContact O-OG1 3.45Å; F333-Q337 WeakPolarHBondContact O-CB 3.28Å; F333-Q337 WeakPolarHBondContact O-CG 3.48Å; F333-Q337 PolarHBondContact O-N 2.86Å; F333-Q337 VanDerWaalsContact O-N 3.14Å
334	Y	72.2	Confident	72	Confident	78 Å²	78	49.7 Å²	49.7	31%	0.306	23%	0.23	S	C	.	.	H	α-helix	trans	-64.9	-48.1	176.2	175.9	-103	0	0	0	112	P330 I331 L332 T336 R341 T344	P330-Y334 VanDerWaalsContact O-CB 3.25Å; P330-Y334 WeakPolarHBondContact O-CB 3.26Å; P330-Y334 PolarHBondContact O-N 3.02Å; I331-Y334 WeakPolarHBondContact O-CB 3.23Å; I331-Y334 PolarHBondContact O-N 3.2Å; L332-Y334 PolarHBondContact O-N 3.15Å; Y334-T336 PolarHBondContact O-N 3.1Å; Y334-R341 HydrophobicContact CE1-CG 4.28Å; Y334-R341 HydrophobicContact CE2-CG 4.23Å; Y334-R341 WeakPolarHBondContact O-CG 3.39Å; Y334-T344 HydrophobicContact CE2-CG2 4.36Å
335	F	65.5	Low	70.4	Confident	113 Å²	113	54.9 Å²	54.9	50%	0.496	25%	0.251	S	S	.	.	H	α-helix	trans	-68.6	-25.9	-179.6	-77.2	-67.5	0	0	0	112.8	I331 L332	I331-F335 HydrophobicContact CG2-CD2 3.73Å; I331-F335 HydrophobicContact CG2-CE2 3.77Å; I331-F335 WeakPolarHBondContact O-CD2 3.49Å; I331-F335 PolarHBondContact O-N 3.46Å; L332-F335 PolarHBondContact O-N 3.37Å
336	T	60.1	Low	68.8	Low	15 Å²	15	64 Å²	64	9%	0.092	29%	0.286	C	S	.	.	H	α-helix	trans	-96.8	-11.4	-175.4	59.5	0	0	0	0	116.4	R271 V275 L332 F333 Y334 P338	R271-T336 VanDerWaalsContact CD-CB 3.41Å; R271-T336 VanDerWaalsContact CD-CG2 3.41Å; R271-T336 WeakPolarHBondContact CD-O 3.32Å; R271-T336 HydrophobicContact CG-CG2 3.45Å; R271-T336 VanDerWaalsContact CG-CG2 3.45Å; V275-T336 HydrophobicContact CB-CG2 4.44Å; V275-T336 HydrophobicContact CG2-CG2 3.22Å; L332-T336 VanDerWaalsContact O-CB 3.32Å; L332-T336 WeakPolarHBondContact O-CB 3.35Å; L332-T336 VanDerWaalsContact O-CG2 3.23Å; L332-T336 WeakPolarHBondContact O-CG2 3.42Å; L332-T336 PolarHBondContact O-N 2.84Å; L332-T336 PolarHBondContact O-OG1 3.43Å; F333-T336 PolarHBondContact O-OG1 3.45Å; Y334-T336 PolarHBondContact O-N 3.1Å; T336-P338 WeakPolarHBondContact O-CD 3.25Å
337	Q	63.1	Low	67.2	Low	19 Å²	19	69 Å²	69	9%	0.089	31%	0.308	C	S	.	.			trans	-107.5	103.5	175.2	-64.1	-169.8	36.7	0	0	111.5	N91 M95 F333 R339 Y340 R341	N91-Q337 PolarHBondContact ND2-NE2 3.45Å; M95-Q337 PolarHBondContact SD-NE2 3.38Å; M95-Q337 VanDerWaalsContact SD-NE2 3.37Å; F333-Q337 WeakPolarHBondContact O-CB 3.28Å; F333-Q337 WeakPolarHBondContact O-CG 3.48Å; F333-Q337 PolarHBondContact O-N 2.86Å; F333-Q337 VanDerWaalsContact O-N 3.14Å; Q337-R339 PolarHBondContact O-N 3.02Å; Q337-Y340 HydrophobicContact CB-CD2 3.75Å; Q337-Y340 HydrophobicContact CB-CG 4.33Å; Q337-Y340 HydrophobicContact CG-CD2 4.38Å; Q337-Y340 PolarHBondContact O-N 3.27Å; Q337-R341 PolarHBondContact O-N 3.12Å
338	P	57.3	Low	65.8	Low	48 Å²	48	73.8 Å²	73.8	31%	0.312	33%	0.332	S	S	.	.	H	α-helix	trans	-55.3	-30.8	177.9	-25.2	31.9	0	0	0	113.5	T336 K342	T336-P338 WeakPolarHBondContact O-CD 3.25Å; P338-K342 WeakPolarHBondContact O-CB 3.32Å; P338-K342 WeakPolarHBondContact O-CG 3.27Å; P338-K342 PolarHBondContact O-N 3.31Å
339	R	56.4	Low	64.5	Low	184 Å²	184	81.3 Å²	81.3	69%	0.694	36%	0.358	S	S	*	.	H	α-helix	trans	-66.2	-36.8	175.2	-71.4	-173.2	176.5	171.4	-1.6	112.4	Q337 S343	Q337-R339 PolarHBondContact O-N 3.02Å; R339-S343 WeakPolarHBondContact O-CB 3.27Å; R339-S343 PolarHBondContact O-N 3.32Å
340	Y	51.9	Low	63.5	Low	30 Å²	30	88.1 Å²	88.1	12%	0.118	39%	0.387	C	S	.	.	H	α-helix	trans	-68.8	-44.5	176.1	-88.5	-100.4	0	0	0	111.3	K80 N92 M95 Q337 S343 T344	K80-Y340 HydrophobicContact CD-CD1 4.16Å; K80-Y340 HydrophobicContact CD-CE1 3.97Å; K80-Y340 PolarHBondContact NZ-O 3.07Å; N92-Y340 PolarHBondContact OD1-OH 3.1Å; M95-Y340 HydrophobicContact CE-CE2 3.78Å; M95-Y340 WeakPolarHBondContact CE-OH 3.31Å; Q337-Y340 HydrophobicContact CB-CD2 3.75Å; Q337-Y340 HydrophobicContact CB-CG 4.33Å; Q337-Y340 HydrophobicContact CG-CD2 4.38Å; Q337-Y340 PolarHBondContact O-N 3.27Å; Y340-S343 PolarHBondContact O-N 3.36Å; Y340-T344 WeakPolarHBondContact O-CB 3.48Å; Y340-T344 PolarHBondContact O-N 3Å; Y340-T344 PolarHBondContact O-OG1 3.34Å; Y340-T344 VanDerWaalsContact O-OG1 3.07Å
341	R	57.1	Low	62.7	Low	108 Å²	108	90.8 Å²	90.8	41%	0.408	40%	0.403	S	S	.	.	H	α-helix	trans	-59.6	-48.5	174.9	-62.9	178.8	78.1	-164.3	4.8	112.2	Y334 Q337 K345	Y334-R341 HydrophobicContact CE1-CG 4.28Å; Y334-R341 HydrophobicContact CE2-CG 4.23Å; Y334-R341 WeakPolarHBondContact O-CG 3.39Å; Q337-R341 PolarHBondContact O-N 3.12Å; R341-K345 WeakPolarHBondContact O-CB 3.46Å; R341-K345 WeakPolarHBondContact O-CG 3.43Å; R341-K345 PolarHBondContact O-N 3.06Å
342	K	58.6	Low	62.1	Low	142 Å²	142	91.9 Å²	91.9	62%	0.617	41%	0.412	S	S	*	.	H	α-helix	trans	-64.8	-39.5	177.9	-71.9	-178	-179.2	-176.9	0	112.2	P338 R346	P338-K342 WeakPolarHBondContact O-CB 3.32Å; P338-K342 WeakPolarHBondContact O-CG 3.27Å; P338-K342 PolarHBondContact O-N 3.31Å; K342-R346 WeakPolarHBondContact O-CG 3.29Å; K342-R346 PolarHBondContact O-N 2.04Å; K342-R346 VanDerWaalsContact O-N 3.09Å
343	S	57.4	Low	61.7	Low	53 Å²	53	93 Å²	93	37%	0.371	42%	0.421	S	S	.	.	H	α-helix	trans	-69.4	-42.8	178.6	168.2	0	0	0	0	112.8	K80 R339 Y340 R346 F347	K80-S343 VanDerWaalsContact CE-OG 3.28Å; K80-S343 WeakPolarHBondContact CE-OG 3.28Å; K80-S343 PolarHBondContact NZ-OG 2.87Å; R339-S343 WeakPolarHBondContact O-CB 3.27Å; R339-S343 PolarHBondContact O-N 3.32Å; Y340-S343 PolarHBondContact O-N 3.36Å; S343-R346 PolarHBondContact O-N 3.07Å; S343-F347 WeakPolarHBondContact O-CB 3.32Å; S343-F347 PolarHBondContact O-N 2.95Å
344	T	56.4	Low	61.1	Low	34 Å²	34	97.8 Å²	97.8	21%	0.209	45%	0.447	C	S	.	.	H	α-helix	trans	-68	-39.5	177	-58.2	0	0	0	0	111.1	K80 Y334 Y340 R346 F347 M348	K80-T344 PolarHBondContact NZ-OG1 3.28Å; K80-T344 VanDerWaalsContact NZ-OG1 3.07Å; Y334-T344 HydrophobicContact CE2-CG2 4.36Å; Y340-T344 WeakPolarHBondContact O-CB 3.48Å; Y340-T344 PolarHBondContact O-N 3Å; Y340-T344 PolarHBondContact O-OG1 3.34Å; Y340-T344 VanDerWaalsContact O-OG1 3.07Å; T344-R346 VanDerWaalsContact C-N 3.34Å; T344-R346 PolarHBondContact O-N 2.85Å; T344-F347 PolarHBondContact O-N 3.24Å; T344-M348 HydrophobicContact CG2-CG 4.15Å; T344-M348 WeakPolarHBondContact O-CB 3.39Å; T344-M348 WeakPolarHBondContact O-CG 3.49Å; T344-M348 PolarHBondContact O-N 2.87Å
345	K	59	Low	60.5	Low	144 Å²	144	103 Å²	103	63%	0.626	47%	0.466	S	S	*	.	H	α-helix	trans	-58.9	-42.3	171.4	-76.4	-175	177.6	-167.6	0	112.5	R341 R349	R341-K345 WeakPolarHBondContact O-CB 3.46Å; R341-K345 WeakPolarHBondContact O-CG 3.43Å; R341-K345 PolarHBondContact O-N 3.06Å; K345-R349 VanDerWaalsContact O-CB 3.3Å; K345-R349 WeakPolarHBondContact O-CB 3.31Å; K345-R349 PolarHBondContact O-N 3.47Å
346	R	59.5	Low	60.1	Low	193 Å²	193	102.3 Å²	102.3	73%	0.728	47%	0.467	S	S	*	.	H	α-helix	trans	-65.8	-42.7	174.7	-74.3	-178	-159.4	-171.8	2.6	112.2	K342 S343 T344 R349 K350	K342-R346 WeakPolarHBondContact O-CG 3.29Å; K342-R346 PolarHBondContact O-N 2.04Å; K342-R346 VanDerWaalsContact O-N 3.09Å; S343-R346 PolarHBondContact O-N 3.07Å; T344-R346 VanDerWaalsContact C-N 3.34Å; T344-R346 PolarHBondContact O-N 2.85Å; R346-R349 PolarHBondContact O-N 3.22Å; R346-K350 WeakPolarHBondContact O-CB 3.29Å; R346-K350 PolarHBondContact O-N 2.97Å
347	F	61.3	Low	60	Low	104 Å²	104	109.1 Å²	109.1	46%	0.456	50%	0.496	S	S	.	.	H	α-helix	trans	-64.7	-49.3	178.6	178.1	-100.7	0	0	0	111.6	R83 S343 T344 R349 K350 V351	R83-F347 VanDerWaalsContact NH1-CZ 3.28Å; S343-F347 WeakPolarHBondContact O-CB 3.32Å; S343-F347 PolarHBondContact O-N 2.95Å; T344-F347 PolarHBondContact O-N 3.24Å; F347-R349 VanDerWaalsContact C-N 3.35Å; F347-R349 PolarHBondContact O-N 3.36Å; F347-K350 WeakPolarHBondContact O-CB 3.43Å; F347-K350 PolarHBondContact O-N 3.05Å; F347-K350 VanDerWaalsContact O-N 3.09Å; F347-V351 HydrophobicContact CD1-CG2 4.19Å; F347-V351 HydrophobicContact CD2-CG2 4.4Å; F347-V351 HydrophobicContact CE1-CG2 3.67Å; F347-V351 HydrophobicContact CE2-CG2 3.9Å; F347-V351 HydrophobicContact CZ-CG2 3.49Å; F347-V351 VanDerWaalsContact CZ-CG2 3.49Å; F347-V351 WeakPolarHBondContact O-CG2 3.48Å; F347-V351 PolarHBondContact O-N 3.28Å
348	M	61.6	Low	59.4	Low	123 Å²	123	111.1 Å²	111.1	61%	0.606	52%	0.521	S	S	*	.	H	α-helix	trans	-52.6	-53.8	173.7	-72.8	-99	-69	0	0	110.1	T344 K350 V351 T352	T344-M348 HydrophobicContact CG2-CG 4.15Å; T344-M348 WeakPolarHBondContact O-CB 3.39Å; T344-M348 WeakPolarHBondContact O-CG 3.49Å; T344-M348 PolarHBondContact O-N 2.87Å; M348-K350 VanDerWaalsContact C-N 3.26Å; M348-K350 PolarHBondContact O-N 3.49Å; M348-V351 PolarHBondContact O-N 3.25Å; M348-T352 PolarHBondContact O-N 3.15Å; M348-T352 PolarHBondContact O-OG1 2.87Å
349	R	61.2	Low	59.2	Low	195 Å²	195	114 Å²	114	74%	0.736	54%	0.538	S	S	*	.	H	α-helix	trans	-56.3	-40	178.2	-164.3	175	-172.6	175.6	2.6	112.3	K345 R346 F347 T352 T353	K345-R349 VanDerWaalsContact O-CB 3.3Å; K345-R349 WeakPolarHBondContact O-CB 3.31Å; K345-R349 PolarHBondContact O-N 3.47Å; R346-R349 PolarHBondContact O-N 3.22Å; F347-R349 VanDerWaalsContact C-N 3.35Å; F347-R349 PolarHBondContact O-N 3.36Å; R349-T352 PolarHBondContact O-N 2.72Å; R349-T353 VanDerWaalsContact O-CG2 3.32Å; R349-T353 WeakPolarHBondContact O-CG2 3.1Å; R349-T353 PolarHBondContact O-N 3.23Å; R349-T353 PolarHBondContact O-OG1 2.63Å
350	K	64.4	Low	58.9	Low	145 Å²	145	109.5 Å²	109.5	63%	0.63	54%	0.535	S	S	*	.	H	α-helix	trans	-67.5	-39.3	178.1	-148.1	175.9	-170.9	-174.3	0	111.9	R346 F347 M348 T353 L354	R346-K350 WeakPolarHBondContact O-CB 3.29Å; R346-K350 PolarHBondContact O-N 2.97Å; F347-K350 WeakPolarHBondContact O-CB 3.43Å; F347-K350 PolarHBondContact O-N 3.05Å; F347-K350 VanDerWaalsContact O-N 3.09Å; M348-K350 VanDerWaalsContact C-N 3.26Å; M348-K350 PolarHBondContact O-N 3.49Å; K350-T353 VanDerWaalsContact C-OG1 3.32Å; K350-T353 VanDerWaalsContact CA-OG1 3.27Å; K350-T353 WeakPolarHBondContact CA-OG1 3.1Å; K350-T353 PolarHBondContact O-OG1 3.17Å; K350-L354 WeakPolarHBondContact O-CB 3.28Å; K350-L354 WeakPolarHBondContact O-CG 3.36Å; K350-L354 PolarHBondContact O-N 3.4Å
351	V	65.1	Low	58.4	Low	69 Å²	69	117.3 Å²	117.3	42%	0.418	59%	0.585	S	S	.	*	H	α-helix	trans	-68.2	-42.1	174.7	173.3	0	0	0	0	111.2	F347 M348 L354 R355	F347-V351 HydrophobicContact CD1-CG2 4.19Å; F347-V351 HydrophobicContact CD2-CG2 4.4Å; F347-V351 HydrophobicContact CE1-CG2 3.67Å; F347-V351 HydrophobicContact CE2-CG2 3.9Å; F347-V351 HydrophobicContact CZ-CG2 3.49Å; F347-V351 VanDerWaalsContact CZ-CG2 3.49Å; F347-V351 WeakPolarHBondContact O-CG2 3.48Å; F347-V351 PolarHBondContact O-N 3.28Å; M348-V351 PolarHBondContact O-N 3.25Å; V351-L354 PolarHBondContact O-N 3.47Å; V351-R355 WeakPolarHBondContact O-CB 3.34Å; V351-R355 PolarHBondContact O-N 3.44Å
352	T	67.6	Low	58.5	Low	75 Å²	75	117.8 Å²	117.8	46%	0.46	59%	0.594	S	S	.	*	H	α-helix	trans	-61.4	-45.8	174.5	-18.8	0	0	0	0	110.7	M348 R349 L354 R355 D356	M348-T352 PolarHBondContact O-N 3.15Å; M348-T352 PolarHBondContact O-OG1 2.87Å; R349-T352 PolarHBondContact O-N 2.72Å; T352-L354 VanDerWaalsContact C-N 3.3Å; T352-L354 PolarHBondContact O-N 2.96Å; T352-R355 WeakPolarHBondContact O-CB 3.26Å; T352-R355 PolarHBondContact O-N 3.1Å; T352-R355 VanDerWaalsContact O-N 3.16Å; T352-D356 PolarHBondContact O-N 3.26Å
353	T	66.4	Low	58.5	Low	66 Å²	66	116.5 Å²	116.5	41%	0.405	59%	0.593	S	S	.	*	H	α-helix	trans	-66.2	-28.4	177.1	51.6	0	0	0	0	114	R349 K350 K357	R349-T353 VanDerWaalsContact O-CG2 3.32Å; R349-T353 WeakPolarHBondContact O-CG2 3.1Å; R349-T353 PolarHBondContact O-N 3.23Å; R349-T353 PolarHBondContact O-OG1 2.63Å; K350-T353 VanDerWaalsContact C-OG1 3.32Å; K350-T353 VanDerWaalsContact CA-OG1 3.27Å; K350-T353 WeakPolarHBondContact CA-OG1 3.1Å; K350-T353 PolarHBondContact O-OG1 3.17Å; T353-K357 WeakPolarHBondContact O-CG 3.45Å; T353-K357 PolarHBondContact O-N 2.76Å
354	L	61.1	Low	58.5	Low	115 Å²	115	120.1 Å²	120.1	60%	0.602	61%	0.605	S	S	*	*	H	α-helix	trans	-77	-32.5	174.7	-76.2	169.2	0	0	0	111.4	K350 V351 T352 K357 G358	K350-L354 WeakPolarHBondContact O-CB 3.28Å; K350-L354 WeakPolarHBondContact O-CG 3.36Å; K350-L354 PolarHBondContact O-N 3.4Å; V351-L354 PolarHBondContact O-N 3.47Å; T352-L354 VanDerWaalsContact C-N 3.3Å; T352-L354 PolarHBondContact O-N 2.96Å; L354-K357 PolarHBondContact O-N 3.03Å; L354-G358 PolarHBondContact O-N 2.85Å; L354-G358 VanDerWaalsContact O-N 3.1Å
355	R	59	Low	58.7	Low	188 Å²	188	125.1 Å²	125.1	71%	0.709	63%	0.629	S	S	*	*	H	α-helix	trans	-68.4	-39.8	173.2	-176	173.8	171.6	171.4	-2.8	112.1	V351 T352 K357 G358 T359	V351-R355 WeakPolarHBondContact O-CB 3.34Å; V351-R355 PolarHBondContact O-N 3.44Å; T352-R355 WeakPolarHBondContact O-CB 3.26Å; T352-R355 PolarHBondContact O-N 3.1Å; T352-R355 VanDerWaalsContact O-N 3.16Å; R355-K357 VanDerWaalsContact C-N 3.32Å; R355-K357 PolarHBondContact O-N 3.09Å; R355-G358 PolarHBondContact O-N 2.67Å; R355-T359 PolarHBondContact O-N 3.33Å; R355-T359 PolarHBondContact O-OG1 2.92Å
356	D	58.2	Low	58.6	Low	99 Å²	99	123.9 Å²	123.9	53%	0.529	63%	0.629	S	S	.	*	H	α-helix	trans	-67.7	-32.3	175.7	-66.2	-15.7	0	0	0	112.2	T352 T359 S360	T352-D356 PolarHBondContact O-N 3.26Å; D356-T359 PolarHBondContact O-OG1 2.87Å; D356-S360 PolarHBondContact O-OG 3.11Å
357	K	56.9	Low	58.6	Low	158 Å²	158	119.3 Å²	119.3	69%	0.687	62%	0.622	S	S	*	*	H	α-helix	trans	-76.5	-23.9	173.8	-76.9	-172.6	175.6	-163.5	0	114.3	T353 L354 R355 S360	T353-K357 WeakPolarHBondContact O-CG 3.45Å; T353-K357 PolarHBondContact O-N 2.76Å; L354-K357 PolarHBondContact O-N 3.03Å; R355-K357 VanDerWaalsContact C-N 3.32Å; R355-K357 PolarHBondContact O-N 3.09Å; K357-S360 WeakPolarHBondContact CA-OG 3.46Å; K357-S360 PolarHBondContact O-OG 3.3Å
358	G	50.6	Low	58.4	Low	60 Å²	60	120.4 Å²	120.4	62%	0.619	63%	0.634	S	S	*	*	H	α-helix	trans	-86.7	-7.7	176.7	0	0	0	0	0	114.3	L354 R355	L354-G358 PolarHBondContact O-N 2.85Å; L354-G358 VanDerWaalsContact O-N 3.1Å; R355-G358 PolarHBondContact O-N 2.67Å
359	T	53.6	Low	58.1	Low	109 Å²	109	120.2 Å²	120.2	67%	0.669	64%	0.636	S	S	*	*	S	Bend	trans	-107.2	3.2	178.4	38.3	0	0	0	0	113	R355 D356	R355-T359 PolarHBondContact O-N 3.33Å; R355-T359 PolarHBondContact O-OG1 2.92Å; D356-T359 PolarHBondContact O-OG1 2.87Å
360	S	49.3	Very low	57.9	Low	90 Å²	90	114 Å²	114	63%	0.629	63%	0.628	S	S	*	*			trans	-108.2	26.3	-179.8	33.5	0	0	0	0	113.2	D356 K357	D356-S360 PolarHBondContact O-OG 3.11Å; K357-S360 WeakPolarHBondContact CA-OG 3.46Å; K357-S360 PolarHBondContact O-OG 3.3Å
361	V	42.5	Very low	57.3	Low	194 Å²	194	111.2 Å²	111.2	100%	1.176	63%	0.628	S	S	*	*			trans	-116.3	0	171.7	-178.5	0	0	0	0	109.6

Retrieved 361 of 361 residues in 192.2 ms (Link to these results)

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