A0A087X8M4_POEFO Loading...

Sodium/glucose cotransporter 2

Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Unlike SLC5A1/SGLT1, requires the auxiliary protein PDZK1IP1/MAP17 for full transporter activity. Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney.

AlphaFold DB , UniProt , Accession A0A087X8M4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 619 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32	Very low	42.3	Very low	249 Å²	249	121.5 Å²	121.5	100%	1.227	68%	0.679	S	S	*	*				0	88.7	0	-151.7	161.5	-174.7	0	0	105.3
2	A	29.2	Very low	44.3	Very low	98 Å²	98	121.9 Å²	121.9	81%	0.81	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-90.8	118.5	-175.7	0	0	0	0	0	107.7
3	E	31.6	Very low	47.1	Very low	190 Å²	190	116.5 Å²	116.5	89%	0.888	65%	0.648	S	S	*	*	P	Polyproline II helix	trans	-65.2	128.4	167.8	-69.6	180	152.3	0	0	108.8
4	P	36.6	Very low	49.8	Very low	123 Å²	123	115.2 Å²	115.2	80%	0.799	65%	0.647	S	S	*	*	P	Polyproline II helix	trans	-81.9	122.8	169.5	28	-22.5	0	0	0	110
5	S	39.2	Very low	52.2	Low	109 Å²	109	110.3 Å²	110.3	76%	0.762	63%	0.627	S	S	*	*	P	Polyproline II helix	trans	-46	126.2	165.7	48.1	0	0	0	0	114.8
6	S	35.4	Very low	54.2	Low	86 Å²	86	103.4 Å²	103.4	60%	0.601	59%	0.588	S	S	*	*			trans	176.7	84.4	139.6	170.7	0	0	0	0	108.3	K8	S6-K8 PolarHBondContact O-N 2.73Å
7	E	39.9	Very low	56	Low	193 Å²	193	102.6 Å²	102.6	90%	0.902	58%	0.581	S	S	*	*			trans	-61.3	92.6	156.7	-100.7	-173.3	151.4	0	0	107.3	V9	E7-V9 VanDerWaalsContact C-N 3.33Å; E7-V9 PolarHBondContact O-N 3.35Å
8	K	48.6	Very low	57.8	Low	149 Å²	149	100.5 Å²	100.5	65%	0.648	58%	0.578	S	S	*	*			trans	-62.2	102	167.5	-75.8	-179.9	178.1	176.1	0	105.9	S6 T10	S6-K8 PolarHBondContact O-N 2.73Å; K8-T10 PolarHBondContact O-N 2.95Å; K8-T10 PolarHBondContact O-OG1 2.8Å
9	V	53.9	Low	59.4	Low	59 Å²	59	97.9 Å²	97.9	36%	0.358	56%	0.564	S	S	.	*			trans	-60.2	93	178.5	-177.7	0	0	0	0	107.6	E7 A160 V362	E7-V9 VanDerWaalsContact C-N 3.33Å; E7-V9 PolarHBondContact O-N 3.35Å; V9-A160 VanDerWaalsContact O-O 3.08Å; V9-V362 HydrophobicContact CB-CG1 3.67Å; V9-V362 HydrophobicContact CG1-CG1 3.45Å; V9-V362 VanDerWaalsContact CG1-CG1 3.45Å; V9-V362 HydrophobicContact CG2-CG1 4.17Å
10	T	55.3	Low	60.7	Low	63 Å²	63	94.5 Å²	94.5	39%	0.387	54%	0.543	S	S	.	.			trans	-91.4	128.4	173.6	-49.4	0	0	0	0	105.1	K8 N12	K8-T10 PolarHBondContact O-N 2.95Å; K8-T10 PolarHBondContact O-OG1 2.8Å; T10-N12 WeakPolarHBondContact CG2-OD1 3.49Å; T10-N12 PolarHBondContact O-N 3.46Å
11	I	63.9	Low	61.9	Low	18 Å²	18	92.3 Å²	92.3	9%	0.092	54%	0.536	C	S	.	.			trans	-60.4	91.4	173.4	-53.2	172.4	0	0	0	108.4	D16 I17 I20 L161 L374	I11-D16 HydrophobicContact CG2-CB 3.42Å; I11-D16 VanDerWaalsContact CG2-CB 3.42Å; I11-I17 HydrophobicContact CG2-CG1 4.11Å; I11-I20 HydrophobicContact CD1-CD1 3.89Å; I11-I20 HydrophobicContact CG2-CD1 4.47Å; I11-L161 HydrophobicContact CB-CD2 4.25Å; I11-L161 HydrophobicContact CD1-CD2 3.6Å; I11-L161 HydrophobicContact CG1-CD2 3.93Å; I11-L374 HydrophobicContact CD1-CD1 3.34Å; I11-L374 HydrophobicContact CG1-CD1 3.93Å
12	N	66.5	Low	64.6	Low	126 Å²	126	82.2 Å²	82.2	67%	0.674	50%	0.496	S	S	*	.			trans	-110.8	4	177.3	-74.1	-12.4	0	0	0	111.6	T10	T10-N12 WeakPolarHBondContact CG2-OD1 3.49Å; T10-N12 PolarHBondContact O-N 3.46Å
13	N	80.5	Confident	67.3	Low	52 Å²	52	77.8 Å²	77.8	28%	0.278	46%	0.458	S	S	.	.			trans	-84.3	123.4	178.3	-171.3	-24.1	0	0	0	110.2	A15 D16 I17 S367	N13-A15 PolarHBondContact O-N 2.88Å; N13-A15 VanDerWaalsContact O-N 3.17Å; N13-A15 WeakPolarHBondContact OD1-CB 3.34Å; N13-A15 PolarHBondContact OD1-N 3.43Å; N13-D16 PolarHBondContact O-N 3.41Å; N13-D16 VanDerWaalsContact O-N 3.13Å; N13-I17 PolarHBondContact O-N 3.49Å; N13-S367 WeakPolarHBondContact ND2-CB 3.27Å
14	P	84.8	Confident	69.9	Low	98 Å²	98	71.5 Å²	71.5	64%	0.636	43%	0.428	S	S	*	.	H	α-helix	trans	-57.2	-29.9	178	22.3	-34.1	0	0	0	113.5	I17 A18	P14-I17 PolarHBondContact O-N 3.26Å; P14-A18 VanDerWaalsContact O-CB 3.27Å; P14-A18 WeakPolarHBondContact O-CB 3.4Å; P14-A18 PolarHBondContact O-N 2.86Å
15	A	85.1	Confident	72.2	Confident	42 Å²	42	71.7 Å²	71.7	35%	0.347	42%	0.422	S	S	.	.	H	α-helix	trans	-64.9	-44	177.2	0	0	0	0	0	112.2	N13 V19	N13-A15 PolarHBondContact O-N 2.88Å; N13-A15 VanDerWaalsContact O-N 3.17Å; N13-A15 WeakPolarHBondContact OD1-CB 3.34Å; N13-A15 PolarHBondContact OD1-N 3.43Å; A15-V19 WeakPolarHBondContact O-CB 3.35Å; A15-V19 VanDerWaalsContact O-CG2 3.23Å; A15-V19 WeakPolarHBondContact O-CG2 3.48Å; A15-V19 PolarHBondContact O-N 3.2Å; A15-V19 VanDerWaalsContact O-N 3.12Å
16	D	84.4	Confident	74.4	Confident	0 Å²	0	70.4 Å²	70.4	0%	0	41%	0.405	C	S	.	.	H	α-helix	trans	-64.9	-44.4	177.9	-72.9	-30.4	0	0	0	110.5	I11 N13 V19 I20 G368 R370 G371	I11-D16 HydrophobicContact CG2-CB 3.42Å; I11-D16 VanDerWaalsContact CG2-CB 3.42Å; N13-D16 PolarHBondContact O-N 3.41Å; N13-D16 VanDerWaalsContact O-N 3.13Å; D16-V19 PolarHBondContact O-N 2.65Å; D16-I20 WeakPolarHBondContact O-CB 3.43Å; D16-I20 WeakPolarHBondContact O-CD1 3.4Å; D16-I20 WeakPolarHBondContact O-CG1 3.42Å; D16-I20 PolarHBondContact O-N 2.85Å; D16-G368 WeakPolarHBondContact OD1-CA 3.43Å; D16-G368 PolarHBondContact OD1-N 3.26Å; D16-R370 IonicContact OD2-CZ 3.43Å; D16-R370 VanDerWaalsContact OD2-CZ 3.31Å; D16-R370 IonicContact OD2-NE 3.84Å; D16-R370 PolarHBondContact OD2-NE 3.19Å; D16-R370 IonicContact OD2-NH2 2.73Å; D16-R370 PolarHBondContact OD2-NH2 2.82Å; D16-G371 WeakPolarHBondContact OD1-CA 3.33Å; D16-G371 PolarHBondContact OD1-N 3.39Å
17	I	85.5	Confident	76.5	Confident	90 Å²	90	67.1 Å²	67.1	46%	0.462	38%	0.381	S	S	.	.	H	α-helix	trans	-63.8	-45.5	-179.9	-61.9	172.1	0	0	0	111.2	I11 N13 P14 V19 I20 A21	I11-I17 HydrophobicContact CG2-CG1 4.11Å; N13-I17 PolarHBondContact O-N 3.49Å; P14-I17 PolarHBondContact O-N 3.26Å; I17-V19 VanDerWaalsContact C-N 3.32Å; I17-V19 PolarHBondContact O-N 2.9Å; I17-I20 PolarHBondContact O-N 3.13Å; I17-A21 WeakPolarHBondContact O-CB 3.43Å; I17-A21 PolarHBondContact O-N 3.46Å
18	A	88.1	Confident	78.5	Confident	64 Å²	64	62.4 Å²	62.4	53%	0.529	36%	0.361	S	S	.	.	H	α-helix	trans	-61.4	-42	178.9	0	0	0	0	0	111.7	P14 G22	P14-A18 VanDerWaalsContact O-CB 3.27Å; P14-A18 WeakPolarHBondContact O-CB 3.4Å; P14-A18 PolarHBondContact O-N 2.86Å; A18-G22 PolarHBondContact O-N 3.42Å
19	V	88.2	Confident	80.1	Confident	51 Å²	51	57 Å²	57	31%	0.309	35%	0.348	S	S	.	.	H	α-helix	trans	-67.3	-42.7	177.3	172.7	0	0	0	0	111.4	A15 D16 I17 G22 Y23 L372	A15-V19 WeakPolarHBondContact O-CB 3.35Å; A15-V19 VanDerWaalsContact O-CG2 3.23Å; A15-V19 WeakPolarHBondContact O-CG2 3.48Å; A15-V19 PolarHBondContact O-N 3.2Å; A15-V19 VanDerWaalsContact O-N 3.12Å; D16-V19 PolarHBondContact O-N 2.65Å; I17-V19 VanDerWaalsContact C-N 3.32Å; I17-V19 PolarHBondContact O-N 2.9Å; V19-G22 PolarHBondContact O-N 3.44Å; V19-Y23 WeakPolarHBondContact O-CB 3.39Å; V19-Y23 PolarHBondContact O-N 3.15Å; V19-L372 HydrophobicContact CG1-CB 3.65Å; V19-L372 HydrophobicContact CG1-CD1 3.92Å; V19-L372 HydrophobicContact CG1-CG 4.36Å
20	I	86.1	Confident	81.4	Confident	30 Å²	30	56.1 Å²	56.1	15%	0.154	34%	0.342	C	S	.	.	H	α-helix	trans	-59.5	-50.4	175.4	-69.1	161.5	0	0	0	110.4	I11 D16 I17 G22 Y23 F24 G371 A375	I11-I20 HydrophobicContact CD1-CD1 3.89Å; I11-I20 HydrophobicContact CG2-CD1 4.47Å; D16-I20 WeakPolarHBondContact O-CB 3.43Å; D16-I20 WeakPolarHBondContact O-CD1 3.4Å; D16-I20 WeakPolarHBondContact O-CG1 3.42Å; D16-I20 PolarHBondContact O-N 2.85Å; I17-I20 PolarHBondContact O-N 3.13Å; I20-G22 PolarHBondContact O-N 3.07Å; I20-Y23 PolarHBondContact O-N 3.28Å; I20-F24 HydrophobicContact CG2-CD2 3.74Å; I20-F24 HydrophobicContact CG2-CE2 3.75Å; I20-F24 VanDerWaalsContact O-CD2 3.32Å; I20-F24 WeakPolarHBondContact O-CD2 3.34Å; I20-F24 PolarHBondContact O-N 3.44Å; I20-G371 WeakPolarHBondContact CG1-O 3.5Å; I20-A375 HydrophobicContact CB-CB 4.19Å; I20-A375 HydrophobicContact CG1-CB 3.92Å; I20-A375 HydrophobicContact CG2-CB 4.21Å
21	A	86	Confident	82.4	Confident	48 Å²	48	53.1 Å²	53.1	40%	0.397	32%	0.324	S	S	.	.	H	α-helix	trans	-61	-46.4	179.5	0	0	0	0	0	111.6	I17 Y23 F24 L25	I17-A21 WeakPolarHBondContact O-CB 3.43Å; I17-A21 PolarHBondContact O-N 3.46Å; A21-Y23 VanDerWaalsContact C-N 3.33Å; A21-Y23 PolarHBondContact O-N 3.39Å; A21-F24 PolarHBondContact O-N 3.44Å; A21-L25 WeakPolarHBondContact O-CB 3.29Å; A21-L25 VanDerWaalsContact O-CG 3.28Å; A21-L25 WeakPolarHBondContact O-CG 3.35Å; A21-L25 PolarHBondContact O-N 3.41Å
22	G	87.7	Confident	83.1	Confident	37 Å²	37	55.2 Å²	55.2	38%	0.381	34%	0.338	S	S	.	.	H	α-helix	trans	-60	-41.3	176.7	0	0	0	0	0	112.8	A18 V19 I20 L25 M26	A18-G22 PolarHBondContact O-N 3.42Å; V19-G22 PolarHBondContact O-N 3.44Å; I20-G22 PolarHBondContact O-N 3.07Å; G22-L25 PolarHBondContact O-N 3.49Å; G22-M26 WeakPolarHBondContact O-CB 3.3Å; G22-M26 PolarHBondContact O-N 3.14Å
23	Y	87.1	Confident	83.9	Confident	5 Å²	5	55.6 Å²	55.6	2%	0.02	33%	0.33	C	S	.	.	H	α-helix	trans	-64	-47.8	176.9	176	-94.8	0	0	0	112.1	V19 I20 A21 L25 M26 V27 F194 V198 L372 A375 V376 A379	V19-Y23 WeakPolarHBondContact O-CB 3.39Å; V19-Y23 PolarHBondContact O-N 3.15Å; I20-Y23 PolarHBondContact O-N 3.28Å; A21-Y23 VanDerWaalsContact C-N 3.33Å; A21-Y23 PolarHBondContact O-N 3.39Å; Y23-L25 PolarHBondContact O-N 3.29Å; Y23-M26 HydrophobicContact CD2-CE 3.94Å; Y23-M26 WeakPolarHBondContact O-CB 3.34Å; Y23-M26 PolarHBondContact O-N 3.48Å; Y23-V27 HydrophobicContact CD1-CG2 4.22Å; Y23-V27 HydrophobicContact CE1-CG2 3.75Å; Y23-V27 HydrophobicContact CE2-CG2 4.12Å; Y23-V27 WeakPolarHBondContact O-CG2 3.34Å; Y23-V27 PolarHBondContact O-N 3.18Å; Y23-F194 HydrophobicContact CD2-CE1 4.28Å; Y23-F194 AromaticContact CE2-CE1 3.71Å; Y23-F194 HydrophobicContact CE2-CE1 3.71Å; Y23-V198 HydrophobicContact CE2-CG2 4.48Å; Y23-L372 HydrophobicContact CD2-CD1 4.26Å; Y23-A375 HydrophobicContact CD1-CB 3.5Å; Y23-A375 VanDerWaalsContact CD1-CB 3.5Å; Y23-A375 HydrophobicContact CE1-CB 4.2Å; Y23-A375 VanDerWaalsContact CE1-O 3.3Å; Y23-A375 WeakPolarHBondContact CE1-O 3.34Å; Y23-A375 HydrophobicContact CG-CB 3.87Å; Y23-V376 HydrophobicContact CD2-CG2 4.01Å; Y23-V376 HydrophobicContact CE1-CG2 4.32Å; Y23-V376 HydrophobicContact CE2-CG2 3.5Å; Y23-A379 HydrophobicContact CE1-CB 3.44Å; Y23-A379 VanDerWaalsContact CE1-CB 3.44Å; Y23-A379 VanDerWaalsContact OH-CB 3.3Å; Y23-A379 WeakPolarHBondContact OH-CB 3.42Å
24	F	84.6	Confident	83.7	Confident	59 Å²	59	53.2 Å²	53.2	26%	0.259	32%	0.318	S	S	.	.	H	α-helix	trans	-63.5	-40.3	177.2	-83.1	-67.7	0	0	0	112.5	I20 A21 M26 V27 I28 L378	I20-F24 HydrophobicContact CG2-CD2 3.74Å; I20-F24 HydrophobicContact CG2-CE2 3.75Å; I20-F24 VanDerWaalsContact O-CD2 3.32Å; I20-F24 WeakPolarHBondContact O-CD2 3.34Å; I20-F24 PolarHBondContact O-N 3.44Å; A21-F24 PolarHBondContact O-N 3.44Å; F24-M26 VanDerWaalsContact C-N 3.3Å; F24-M26 PolarHBondContact O-N 3.45Å; F24-V27 PolarHBondContact O-N 3.22Å; F24-I28 WeakPolarHBondContact O-CB 3.25Å; F24-I28 VanDerWaalsContact O-CG1 3.23Å; F24-I28 WeakPolarHBondContact O-CG1 3.39Å; F24-I28 PolarHBondContact O-N 3.12Å; F24-L378 HydrophobicContact CZ-CB 3.9Å; F24-L378 HydrophobicContact CZ-CD1 4.48Å
25	L	86.1	Confident	83.1	Confident	126 Å²	126	50.8 Å²	50.8	66%	0.66	30%	0.298	S	S	*	.	H	α-helix	trans	-59.9	-41	174.5	-73.7	172.6	0	0	0	111.8	A21 G22 Y23 G29	A21-L25 WeakPolarHBondContact O-CB 3.29Å; A21-L25 VanDerWaalsContact O-CG 3.28Å; A21-L25 WeakPolarHBondContact O-CG 3.35Å; A21-L25 PolarHBondContact O-N 3.41Å; G22-L25 PolarHBondContact O-N 3.49Å; Y23-L25 PolarHBondContact O-N 3.29Å; L25-G29 PolarHBondContact O-N 3.04Å
26	M	83.9	Confident	82.7	Confident	83 Å²	83	55.8 Å²	55.8	41%	0.409	32%	0.318	S	S	.	.	H	α-helix	trans	-66.6	-44.7	176.2	178.1	176.2	47.8	0	0	112.1	G22 Y23 F24 I28 G29 V30 F194	G22-M26 WeakPolarHBondContact O-CB 3.3Å; G22-M26 PolarHBondContact O-N 3.14Å; Y23-M26 HydrophobicContact CD2-CE 3.94Å; Y23-M26 WeakPolarHBondContact O-CB 3.34Å; Y23-M26 PolarHBondContact O-N 3.48Å; F24-M26 VanDerWaalsContact C-N 3.3Å; F24-M26 PolarHBondContact O-N 3.45Å; M26-I28 PolarHBondContact O-N 3.5Å; M26-G29 WeakPolarHBondContact O-CA 3.02Å; M26-G29 PolarHBondContact O-N 3.49Å; M26-G29 VanDerWaalsContact O-N 3.15Å; M26-V30 WeakPolarHBondContact O-CG2 3.47Å; M26-V30 PolarHBondContact O-N 3.09Å; M26-F194 HydrophobicContact CE-CE1 3.45Å; M26-F194 VanDerWaalsContact CE-CE1 3.45Å; M26-F194 HydrophobicContact CE-CE2 4.2Å; M26-F194 HydrophobicContact CE-CZ 3.15Å; M26-F194 HydrophobicContact CG-CZ 4.45Å; M26-F194 HydrophobicContact SD-CE1 4.08Å; M26-F194 HydrophobicContact SD-CE2 3.98Å; M26-F194 HydrophobicContact SD-CZ 3.48Å; M26-F194 WeakPolarHBondContact SD-CZ 3.3Å
27	V	81.1	Confident	82	Confident	16 Å²	16	65.5 Å²	65.5	10%	0.097	36%	0.355	C	S	.	.	H	α-helix	trans	-62	-44.6	177.2	172	0	0	0	0	111	Y23 F24 G29 V30 G31 T191 F194	Y23-V27 HydrophobicContact CD1-CG2 4.22Å; Y23-V27 HydrophobicContact CE1-CG2 3.75Å; Y23-V27 HydrophobicContact CE2-CG2 4.12Å; Y23-V27 WeakPolarHBondContact O-CG2 3.34Å; Y23-V27 PolarHBondContact O-N 3.18Å; F24-V27 PolarHBondContact O-N 3.22Å; V27-G29 VanDerWaalsContact C-N 3.31Å; V27-G29 PolarHBondContact O-N 3.14Å; V27-V30 PolarHBondContact O-N 3.1Å; V27-G31 PolarHBondContact O-N 2.81Å; V27-T191 HydrophobicContact CG1-CG2 4.07Å; V27-F194 HydrophobicContact CG2-CD1 4.42Å; V27-F194 HydrophobicContact CG2-CE1 4.48Å
28	I	80.7	Confident	81.2	Confident	94 Å²	94	62.8 Å²	62.8	48%	0.482	34%	0.343	S	S	.	.	H	α-helix	trans	-61.2	-43.3	173.8	-68.4	167.3	0	0	0	109.9	F24 M26 G31 V32	F24-I28 WeakPolarHBondContact O-CB 3.25Å; F24-I28 VanDerWaalsContact O-CG1 3.23Å; F24-I28 WeakPolarHBondContact O-CG1 3.39Å; F24-I28 PolarHBondContact O-N 3.12Å; M26-I28 PolarHBondContact O-N 3.5Å; I28-G31 CarbonylContact O-C 3.25Å; I28-G31 WeakPolarHBondContact O-CA 3.47Å; I28-G31 PolarHBondContact O-N 2.78Å; I28-V32 HydrophobicContact CG2-CG2 4.1Å; I28-V32 WeakPolarHBondContact O-CB 3.45Å; I28-V32 VanDerWaalsContact O-CG2 3.27Å; I28-V32 WeakPolarHBondContact O-CG2 3.42Å; I28-V32 PolarHBondContact O-N 3.39Å
29	G	82.4	Confident	80	Confident	37 Å²	37	66 Å²	66	38%	0.381	35%	0.351	S	S	.	.	H	α-helix	trans	-58.4	-47.7	176.8	0	0	0	0	0	113.1	L25 M26 V27 G31 V32 W33	L25-G29 PolarHBondContact O-N 3.04Å; M26-G29 WeakPolarHBondContact O-CA 3.02Å; M26-G29 PolarHBondContact O-N 3.49Å; M26-G29 VanDerWaalsContact O-N 3.15Å; V27-G29 VanDerWaalsContact C-N 3.31Å; V27-G29 PolarHBondContact O-N 3.14Å; G29-G31 VanDerWaalsContact C-N 3.32Å; G29-G31 PolarHBondContact O-N 3.22Å; G29-V32 PolarHBondContact O-N 3.14Å; G29-W33 WeakPolarHBondContact O-CB 3.36Å; G29-W33 PolarHBondContact O-N 3.03Å
30	V	80.5	Confident	78.9	Confident	39 Å²	39	67 Å²	67	24%	0.236	35%	0.349	C	S	.	.	H	α-helix	trans	-62.2	-42.2	174.7	172.4	0	0	0	0	110.8	M26 V27 S34 T191	M26-V30 WeakPolarHBondContact O-CG2 3.47Å; M26-V30 PolarHBondContact O-N 3.09Å; V27-V30 PolarHBondContact O-N 3.1Å; V30-S34 WeakPolarHBondContact O-CB 3.35Å; V30-S34 PolarHBondContact O-N 3.5Å; V30-T191 HydrophobicContact CB-CG2 4.41Å; V30-T191 HydrophobicContact CG1-CG2 4.1Å
31	G	76.9	Confident	77.7	Confident	1 Å²	1	68 Å²	68	1%	0.01	37%	0.366	C	S	.	.	H	α-helix	trans	-56.3	-59.9	174.5	0	0	0	0	0	111.4	V27 I28 G29 W33 S34 M35	V27-G31 PolarHBondContact O-N 2.81Å; I28-G31 CarbonylContact O-C 3.25Å; I28-G31 WeakPolarHBondContact O-CA 3.47Å; I28-G31 PolarHBondContact O-N 2.78Å; G29-G31 VanDerWaalsContact C-N 3.32Å; G29-G31 PolarHBondContact O-N 3.22Å; G31-W33 PolarHBondContact O-N 2.76Å; G31-S34 WeakPolarHBondContact O-CB 3.46Å; G31-S34 PolarHBondContact O-N 3.34Å; G31-S34 VanDerWaalsContact O-N 3.15Å; G31-M35 WeakPolarHBondContact O-CG 3.5Å; G31-M35 PolarHBondContact O-N 3.22Å
32	V	79.5	Confident	77.1	Confident	62 Å²	62	68.4 Å²	68.4	38%	0.376	36%	0.364	S	S	.	.	H	α-helix	trans	-54.7	-46.8	177.9	174.8	0	0	0	0	111.5	I28 G29 S34 M35 L36	I28-V32 HydrophobicContact CG2-CG2 4.1Å; I28-V32 WeakPolarHBondContact O-CB 3.45Å; I28-V32 VanDerWaalsContact O-CG2 3.27Å; I28-V32 WeakPolarHBondContact O-CG2 3.42Å; I28-V32 PolarHBondContact O-N 3.39Å; G29-V32 PolarHBondContact O-N 3.14Å; V32-S34 VanDerWaalsContact C-N 3.34Å; V32-S34 PolarHBondContact O-N 2.83Å; V32-M35 HydrophobicContact CB-CE 4.26Å; V32-M35 HydrophobicContact CG2-CE 3.66Å; V32-M35 VanDerWaalsContact O-CB 3.23Å; V32-M35 WeakPolarHBondContact O-CB 3.47Å; V32-M35 PolarHBondContact O-N 3.02Å; V32-M35 VanDerWaalsContact O-N 3.09Å; V32-L36 HydrophobicContact CG1-CD1 4.18Å; V32-L36 WeakPolarHBondContact O-CG 3.43Å; V32-L36 PolarHBondContact O-N 2.97Å; V32-L36 VanDerWaalsContact O-N 3.08Å
33	W	82.6	Confident	76.2	Confident	133 Å²	133	67.2 Å²	67.2	50%	0.504	35%	0.35	S	S	.	.	H	α-helix	trans	-58.8	-44.7	177.3	172.8	79.8	0	0	0	112.2	G29 G31 M35 L36 R37	G29-W33 WeakPolarHBondContact O-CB 3.36Å; G29-W33 PolarHBondContact O-N 3.03Å; G31-W33 PolarHBondContact O-N 2.76Å; W33-M35 VanDerWaalsContact C-N 3.31Å; W33-M35 PolarHBondContact O-N 2.86Å; W33-L36 PolarHBondContact O-N 3.44Å; W33-R37 PolarHBondContact O-N 3.41Å
34	S	76.4	Confident	75	Confident	3 Å²	3	68.3 Å²	68.3	2%	0.021	36%	0.363	C	S	.	.	H	α-helix	trans	-64.9	-36.8	175	173.8	0	0	0	0	112.1	V30 G31 V32 L36 R37 T38 A187 Y190	V30-S34 WeakPolarHBondContact O-CB 3.35Å; V30-S34 PolarHBondContact O-N 3.5Å; G31-S34 WeakPolarHBondContact O-CB 3.46Å; G31-S34 PolarHBondContact O-N 3.34Å; G31-S34 VanDerWaalsContact O-N 3.15Å; V32-S34 VanDerWaalsContact C-N 3.34Å; V32-S34 PolarHBondContact O-N 2.83Å; S34-L36 VanDerWaalsContact C-N 3.31Å; S34-L36 PolarHBondContact O-N 3.36Å; S34-R37 PolarHBondContact O-N 2.74Å; S34-T38 PolarHBondContact O-N 3.48Å; S34-T38 PolarHBondContact O-OG1 3.49Å; S34-A187 WeakPolarHBondContact OG-CA 3.5Å; S34-Y190 WeakPolarHBondContact OG-CD2 3.19Å
35	M	72.4	Confident	74	Confident	46 Å²	46	65.9 Å²	65.9	23%	0.227	35%	0.354	C	S	.	.	H	α-helix	trans	-58.3	-43.5	177.3	-54.6	-144.7	-114.6	0	0	111.9	G31 V32 W33 R37 R40	G31-M35 WeakPolarHBondContact O-CG 3.5Å; G31-M35 PolarHBondContact O-N 3.22Å; V32-M35 HydrophobicContact CB-CE 4.26Å; V32-M35 HydrophobicContact CG2-CE 3.66Å; V32-M35 VanDerWaalsContact O-CB 3.23Å; V32-M35 WeakPolarHBondContact O-CB 3.47Å; V32-M35 PolarHBondContact O-N 3.02Å; V32-M35 VanDerWaalsContact O-N 3.09Å; W33-M35 VanDerWaalsContact C-N 3.31Å; W33-M35 PolarHBondContact O-N 2.86Å; M35-R37 VanDerWaalsContact C-N 3.3Å; M35-R37 PolarHBondContact O-N 3.35Å; M35-R40 VanDerWaalsContact CB-CZ 3.4Å; M35-R40 VanDerWaalsContact CB-NH1 3.28Å; M35-R40 VanDerWaalsContact CB-NH2 3.29Å; M35-R40 VanDerWaalsContact CG-CZ 3.49Å; M35-R40 VanDerWaalsContact SD-CZ 3.56Å; M35-R40 PolarHBondContact SD-NH1 3.24Å; M35-R40 PolarHBondContact SD-NH2 3.4Å
36	L	75.6	Confident	73.3	Confident	147 Å²	147	60.4 Å²	60.4	77%	0.77	33%	0.325	S	S	*	.	H	α-helix	trans	-72.5	-22.5	-175.8	-65.9	171.8	0	0	0	113.1	V32 W33 S34	V32-L36 HydrophobicContact CG1-CD1 4.18Å; V32-L36 WeakPolarHBondContact O-CG 3.43Å; V32-L36 PolarHBondContact O-N 2.97Å; V32-L36 VanDerWaalsContact O-N 3.08Å; W33-L36 PolarHBondContact O-N 3.44Å; S34-L36 VanDerWaalsContact C-N 3.31Å; S34-L36 PolarHBondContact O-N 3.36Å
37	R	71.4	Confident	72.6	Confident	204 Å²	204	56.5 Å²	56.5	77%	0.77	31%	0.305	S	S	*	.	H	α-helix	trans	-96.1	-13.2	179.4	-82	-150.1	175.3	-165.3	1.9	115.2	W33 S34 M35	W33-R37 PolarHBondContact O-N 3.41Å; S34-R37 PolarHBondContact O-N 2.74Å; M35-R37 VanDerWaalsContact C-N 3.3Å; M35-R37 PolarHBondContact O-N 3.35Å
38	T	66.9	Low	72	Confident	34 Å²	34	56.2 Å²	56.2	21%	0.209	30%	0.303	C	S	.	.	S	Bend	trans	-104.9	131.1	-172.3	-47.2	0	0	0	0	111.2	S34 R40 A186	S34-T38 PolarHBondContact O-N 3.48Å; S34-T38 PolarHBondContact O-OG1 3.49Å; T38-R40 PolarHBondContact O-N 3.29Å; T38-A186 HydrophobicContact CG2-CB 3.79Å
39	N	64.1	Low	71.6	Confident	131 Å²	131	51.8 Å²	51.8	70%	0.701	28%	0.28	S	S	*	.			trans	-76.3	108.1	178.8	-154.9	-11.4	0	0	0	110.6	G45	N39-G45 WeakPolarHBondContact O-CA 3.49Å
40	R	64.9	Low	70.8	Confident	72 Å²	72	52.5 Å²	52.5	27%	0.272	29%	0.288	S	S	.	.			trans	-100.3	-1.8	-172.3	-72	170.5	165.8	-176.5	-8.5	114.9	M35 T38 T42 T182 G183	M35-R40 VanDerWaalsContact CB-CZ 3.4Å; M35-R40 VanDerWaalsContact CB-NH1 3.28Å; M35-R40 VanDerWaalsContact CB-NH2 3.29Å; M35-R40 VanDerWaalsContact CG-CZ 3.49Å; M35-R40 VanDerWaalsContact SD-CZ 3.56Å; M35-R40 PolarHBondContact SD-NH1 3.24Å; M35-R40 PolarHBondContact SD-NH2 3.4Å; T38-R40 PolarHBondContact O-N 3.29Å; R40-T42 PolarHBondContact O-N 3.45Å; R40-T182 VanDerWaalsContact CZ-O 3.29Å; R40-T182 PolarHBondContact NH1-O 2.84Å; R40-T182 VanDerWaalsContact NH1-O 3.08Å; R40-T182 PolarHBondContact NH2-O 3.24Å; R40-T182 VanDerWaalsContact NH2-O 3.14Å; R40-G183 VanDerWaalsContact NH2-C 3.27Å; R40-G183 PolarHBondContact NH2-O 2.79Å
41	G	61.7	Low	70.5	Confident	50 Å²	50	55.8 Å²	55.8	52%	0.515	30%	0.296	S	S	.	.	S	Bend	trans	-65.7	-17.7	-178	0	0	0	0	0	113.7
42	T	73.1	Confident	70.8	Confident	58 Å²	58	59 Å²	59	36%	0.356	32%	0.318	S	S	.	.	S	Bend	trans	-116.5	153.7	-173.1	68.2	0	0	0	0	112.6	R40 G44 G45 Y46	R40-T42 PolarHBondContact O-N 3.45Å; T42-G44 VanDerWaalsContact C-N 3.29Å; T42-G44 PolarHBondContact O-N 3.14Å; T42-G45 PolarHBondContact O-N 3.04Å; T42-G45 VanDerWaalsContact O-N 3.12Å; T42-G45 PolarHBondContact OG1-N 3.04Å; T42-Y46 PolarHBondContact O-N 3.44Å
43	V	67.3	Low	71.1	Confident	12 Å²	12	56.1 Å²	56.1	7%	0.073	30%	0.301	C	S	.	.	H	α-helix	trans	-58.1	-41.9	177.2	174.5	0	0	0	0	110.9	G45 Y46 F47 M398 E410 L413	V43-G45 PolarHBondContact O-N 2.92Å; V43-Y46 PolarHBondContact O-N 3.14Å; V43-F47 HydrophobicContact CB-CD2 4.41Å; V43-F47 HydrophobicContact CG1-CD2 3.58Å; V43-F47 HydrophobicContact CG1-CE2 4.01Å; V43-F47 WeakPolarHBondContact O-CB 3.46Å; V43-F47 WeakPolarHBondContact O-CD2 3.31Å; V43-F47 PolarHBondContact O-N 3Å; V43-M398 HydrophobicContact CG1-CE 4.07Å; V43-M398 HydrophobicContact CG1-SD 3.88Å; V43-E410 HydrophobicContact CG2-CB 4.05Å; V43-E410 HydrophobicContact CG2-CG 3.94Å; V43-E410 PolarHBondContact N-OE1 3.17Å; V43-L413 HydrophobicContact CG2-CD1 4.08Å
44	G	63.5	Low	71.6	Confident	28 Å²	28	50.7 Å²	50.7	29%	0.289	28%	0.284	S	S	.	.	H	α-helix	trans	-67	-32.7	177.1	0	0	0	0	0	113.8	T42 L48 A49 G50	T42-G44 VanDerWaalsContact C-N 3.29Å; T42-G44 PolarHBondContact O-N 3.14Å; G44-L48 CarbonylContact O-C 3.58Å; G44-L48 WeakPolarHBondContact O-CA 3.48Å; G44-L48 WeakPolarHBondContact O-CB 3.47Å; G44-L48 PolarHBondContact O-N 3.45Å; G44-A49 PolarHBondContact O-N 3.48Å; G44-G50 PolarHBondContact O-N 3.33Å
45	G	63.9	Low	72.4	Confident	7 Å²	7	56 Å²	56	7%	0.072	30%	0.304	C	S	.	.	H	α-helix	trans	-68.7	-46.2	174.6	0	0	0	0	0	112.5	N39 T42 V43 A49	N39-G45 WeakPolarHBondContact O-CA 3.49Å; T42-G45 PolarHBondContact O-N 3.04Å; T42-G45 VanDerWaalsContact O-N 3.12Å; T42-G45 PolarHBondContact OG1-N 3.04Å; V43-G45 PolarHBondContact O-N 2.92Å; G45-A49 PolarHBondContact O-N 3.4Å
46	Y	70.6	Confident	73.4	Confident	12 Å²	12	58.8 Å²	58.8	5%	0.047	31%	0.312	C	S	.	.	H	α-helix	trans	-72.4	-45.6	-178.9	-171.9	-100.8	0	0	0	113	T42 V43 T180 G184 L185	T42-Y46 PolarHBondContact O-N 3.44Å; V43-Y46 PolarHBondContact O-N 3.14Å; Y46-T180 PolarHBondContact OH-O 3.26Å; Y46-G184 VanDerWaalsContact CE2-CA 3.44Å; Y46-L185 WeakPolarHBondContact O-CB 3.39Å; Y46-L185 PolarHBondContact O-N 2.9Å
47	F	68.2	Low	74.2	Confident	1 Å²	1	51.9 Å²	51.9	0%	0.004	28%	0.276	C	S	.	.	H	α-helix	trans	-96.9	-18.1	-172.8	-64.1	-65.5	0	0	0	115.7	V43 L185 Q290 T394	V43-F47 HydrophobicContact CB-CD2 4.41Å; V43-F47 HydrophobicContact CG1-CD2 3.58Å; V43-F47 HydrophobicContact CG1-CE2 4.01Å; V43-F47 WeakPolarHBondContact O-CB 3.46Å; V43-F47 WeakPolarHBondContact O-CD2 3.31Å; V43-F47 PolarHBondContact O-N 3Å; F47-L185 WeakPolarHBondContact O-CD2 3.45Å; F47-Q290 PolarHBondContact O-NE2 3.38Å; F47-T394 HydrophobicContact CB-CG2 4.48Å; F47-T394 HydrophobicContact CD1-CG2 4.15Å; F47-T394 WeakPolarHBondContact CD1-OG1 3.47Å; F47-T394 WeakPolarHBondContact CE1-OG1 3.38Å; F47-T394 HydrophobicContact CG-CG2 4.29Å
48	L	69.8	Low	75.2	Confident	9 Å²	9	42.1 Å²	42.1	5%	0.047	24%	0.239	C	C	.	.	H	α-helix	trans	-123.2	8.1	-178.9	-69.6	173.8	0	0	0	113.5	G44 G50 R51 I114 Q290 L293 A294	G44-L48 CarbonylContact O-C 3.58Å; G44-L48 WeakPolarHBondContact O-CA 3.48Å; G44-L48 WeakPolarHBondContact O-CB 3.47Å; G44-L48 PolarHBondContact O-N 3.45Å; L48-G50 PolarHBondContact O-N 3.32Å; L48-R51 PolarHBondContact O-N 3.47Å; L48-I114 HydrophobicContact CD1-CD1 4.18Å; L48-I114 HydrophobicContact CD1-CG1 4.03Å; L48-I114 HydrophobicContact CD1-CG2 4.15Å; L48-I114 HydrophobicContact CD2-CG2 4.21Å; L48-I114 HydrophobicContact CG-CG2 4.15Å; L48-Q290 HydrophobicContact CD2-CG 4.49Å; L48-L293 HydrophobicContact CD2-CB 4.09Å; L48-A294 WeakPolarHBondContact O-CB 3.39Å
49	A	72.3	Confident	76.6	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.008	23%	0.229	C	C	.	.	G	3₁₀ helix	trans	51.1	28.9	-176.1	0	0	0	0	0	113.7	G44 G45 R51 S52 M53 A186 A294	G44-A49 PolarHBondContact O-N 3.48Å; G45-A49 PolarHBondContact O-N 3.4Å; A49-R51 PolarHBondContact O-N 2.98Å; A49-R51 VanDerWaalsContact O-N 3.17Å; A49-S52 PolarHBondContact O-OG 3.5Å; A49-M53 HydrophobicContact CB-CE 3.54Å; A49-M53 HydrophobicContact CB-CG 4.29Å; A49-A186 HydrophobicContact CB-CB 3.65Å; A49-A294 HydrophobicContact CB-CB 4.37Å
50	G	65.1	Low	78	Confident	52 Å²	52	34.5 Å²	34.5	54%	0.536	20%	0.197	S	C	.	.	G	3₁₀ helix	trans	62.3	18.4	-178.5	0	0	0	0	0	115.5	G44 L48 S52	G44-G50 PolarHBondContact O-N 3.33Å; L48-G50 PolarHBondContact O-N 3.32Å; G50-S52 VanDerWaalsContact C-N 3.32Å; G50-S52 PolarHBondContact O-N 2.97Å
51	R	74.2	Confident	79.3	Confident	108 Å²	108	31 Å²	31	41%	0.408	18%	0.184	S	C	.	.	G	3₁₀ helix	trans	52.7	44.2	-178.4	-60.7	-172.3	169.9	160.2	-0.4	113.8	L48 A49 A294 R296	L48-R51 PolarHBondContact O-N 3.47Å; A49-R51 PolarHBondContact O-N 2.98Å; A49-R51 VanDerWaalsContact O-N 3.17Å; R51-A294 CarbonylContact C-O 3.5Å; R51-A294 VanDerWaalsContact CA-O 3.25Å; R51-A294 WeakPolarHBondContact CA-O 3.42Å; R51-R296 VanDerWaalsContact O-CA 3.24Å; R51-R296 WeakPolarHBondContact O-CA 3.38Å
52	S	82.8	Confident	80.7	Confident	69 Å²	69	28.7 Å²	28.7	48%	0.483	16%	0.16	S	C	.	.			trans	-113.5	0.5	-174.5	61.8	0	0	0	0	113.8	A49 G50 A294	A49-S52 PolarHBondContact O-OG 3.5Å; G50-S52 VanDerWaalsContact C-N 3.32Å; G50-S52 PolarHBondContact O-N 2.97Å; S52-A294 PolarHBondContact N-O 3.06Å
53	M	86.6	Confident	81.7	Confident	1 Å²	1	26.1 Å²	26.1	1%	0.005	14%	0.144	C	C	.	.	B	Isolated β-bridge	trans	-75.5	138.5	-167.5	-65.5	-67.2	177.6	0	0	113.2	A49 V58 A186 M189 Y190 A294 R296	A49-M53 HydrophobicContact CB-CE 3.54Å; A49-M53 HydrophobicContact CB-CG 4.29Å; M53-V58 HydrophobicContact CB-CG2 3.91Å; M53-A186 HydrophobicContact CE-CB 3.83Å; M53-M189 HydrophobicContact CB-CE 3.95Å; M53-M189 HydrophobicContact CE-CB 4Å; M53-M189 HydrophobicContact CE-SD 4.24Å; M53-M189 HydrophobicContact CG-CE 3.7Å; M53-M189 HydrophobicContact CG-SD 3.78Å; M53-M189 HydrophobicContact SD-CB 4.32Å; M53-M189 HydrophobicContact SD-CE 4.33Å; M53-M189 HydrophobicContact SD-SD 4.38Å; M53-Y190 HydrophobicContact CE-CD2 4.17Å; M53-Y190 HydrophobicContact CE-CE2 3.75Å; M53-Y190 HydrophobicContact SD-CE2 4.18Å; M53-A294 WeakPolarHBondContact CB-O 3Å; M53-A294 HydrophobicContact CG-CB 4.23Å; M53-A294 PolarHBondContact N-O 3.45Å; M53-R296 PolarHBondContact O-N 2.91Å
54	A	92.1	Very high	82.8	Confident	19 Å²	19	25.5 Å²	25.5	16%	0.157	14%	0.14	C	C	.	.			trans	-81.1	162.7	177.1	0	0	0	0	0	112	W56 S57 V58 H300	A54-W56 VanDerWaalsContact C-N 3.33Å; A54-W56 HydrophobicContact CB-CD2 4.48Å; A54-W56 HydrophobicContact CB-CG 4.48Å; A54-W56 HydrophobicContact CB-CZ2 4.27Å; A54-W56 PolarHBondContact O-N 3.36Å; A54-S57 PolarHBondContact O-N 3.08Å; A54-V58 VanDerWaalsContact O-CG2 3.31Å; A54-V58 WeakPolarHBondContact O-CG2 3.47Å; A54-V58 PolarHBondContact O-N 3.09Å; A54-H300 WeakPolarHBondContact CA-ND1 3.25Å
55	W	93.9	Very high	83.9	Confident	114 Å²	114	24.7 Å²	24.7	43%	0.432	13%	0.13	S	C	.	.	H	α-helix	trans	-64.8	-37.4	-171	58.8	-100.3	0	0	0	112.4	V58 G59 H300 A303 G304 V307	W55-V58 PolarHBondContact O-N 2.93Å; W55-G59 PolarHBondContact O-N 3.07Å; W55-H300 HydrophobicContact CB-CB 4.31Å; W55-H300 WeakPolarHBondContact CB-O 3.39Å; W55-H300 AromaticContact CD1-CE1 3.45Å; W55-H300 VanDerWaalsContact CD1-CE1 3.45Å; W55-H300 AromaticContact CD1-ND1 3.76Å; W55-H300 PolarHBondContact N-ND1 3.25Å; W55-A303 HydrophobicContact CB-CB 3.62Å; W55-A303 HydrophobicContact CD2-CB 4.49Å; W55-A303 HydrophobicContact CG-CB 4.05Å; W55-G304 VanDerWaalsContact O-CA 3.25Å; W55-G304 WeakPolarHBondContact O-CA 3.11Å; W55-V307 HydrophobicContact CE3-CG2 3.62Å; W55-V307 HydrophobicContact CZ3-CG2 3.5Å
56	W	92.9	Very high	85.1	Confident	106 Å²	106	25.1 Å²	25.1	40%	0.402	13%	0.131	S	C	.	.	H	α-helix	trans	-67.4	-39.8	179.2	53.6	-98.6	0	0	0	111.2	A54 G59 A60 Y190 T193	A54-W56 VanDerWaalsContact C-N 3.33Å; A54-W56 HydrophobicContact CB-CD2 4.48Å; A54-W56 HydrophobicContact CB-CG 4.48Å; A54-W56 HydrophobicContact CB-CZ2 4.27Å; A54-W56 PolarHBondContact O-N 3.36Å; W56-G59 PolarHBondContact O-N 2.92Å; W56-A60 VanDerWaalsContact O-CB 3.25Å; W56-A60 WeakPolarHBondContact O-CB 3.27Å; W56-A60 PolarHBondContact O-N 3.11Å; W56-Y190 HydrophobicContact CH2-CE1 4.22Å; W56-T193 HydrophobicContact CE3-CG2 3.47Å; W56-T193 VanDerWaalsContact CE3-CG2 3.47Å; W56-T193 HydrophobicContact CZ3-CG2 3.43Å; W56-T193 VanDerWaalsContact CZ3-CG2 3.43Å
57	S	92.8	Very high	85.9	Confident	1 Å²	1	24.5 Å²	24.5	1%	0.007	13%	0.128	C	C	.	.	H	α-helix	trans	-70.5	-39.8	176.7	-177.4	0	0	0	0	111.7	A54 S61 T193	A54-S57 PolarHBondContact O-N 3.08Å; S57-S61 WeakPolarHBondContact O-CB 3.11Å; S57-S61 PolarHBondContact O-N 3.41Å; S57-T193 WeakPolarHBondContact CA-OG1 3.44Å; S57-T193 PolarHBondContact OG-OG1 2.98Å
58	V	93.6	Very high	86.5	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-60.4	-49.8	173.1	173.6	0	0	0	0	110.4	M53 A54 W55 S61 L62 M189 A295	M53-V58 HydrophobicContact CB-CG2 3.91Å; A54-V58 VanDerWaalsContact O-CG2 3.31Å; A54-V58 WeakPolarHBondContact O-CG2 3.47Å; A54-V58 PolarHBondContact O-N 3.09Å; W55-V58 PolarHBondContact O-N 2.93Å; V58-S61 PolarHBondContact O-N 3.32Å; V58-L62 HydrophobicContact CG1-CD1 3.91Å; V58-L62 HydrophobicContact CG1-CG 4.37Å; V58-L62 WeakPolarHBondContact O-CB 3.5Å; V58-L62 WeakPolarHBondContact O-CG 3.4Å; V58-L62 PolarHBondContact O-N 2.97Å; V58-M189 HydrophobicContact CG2-CE 4.14Å; V58-A295 HydrophobicContact CG2-CB 3.87Å
59	G	95	Very high	86.8	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-63.8	-45	-179.4	0	0	0	0	0	113.5	W55 W56 L62 F63 G304	W55-G59 PolarHBondContact O-N 3.07Å; W56-G59 PolarHBondContact O-N 2.92Å; G59-L62 PolarHBondContact O-N 2.86Å; G59-F63 PolarHBondContact O-N 3.35Å; G59-G304 WeakPolarHBondContact CA-O 3.08Å
60	A	93.2	Very high	87.4	Confident	4 Å²	4	24.3 Å²	24.3	3%	0.033	13%	0.128	C	C	.	.	H	α-helix	trans	-65.1	-44.1	176.9	0	0	0	0	0	111.6	W56 L62 F63 A64 T193 T196	W56-A60 VanDerWaalsContact O-CB 3.25Å; W56-A60 WeakPolarHBondContact O-CB 3.27Å; W56-A60 PolarHBondContact O-N 3.11Å; A60-L62 PolarHBondContact O-N 3.44Å; A60-F63 WeakPolarHBondContact O-CB 3.38Å; A60-F63 PolarHBondContact O-N 3.29Å; A60-A64 WeakPolarHBondContact O-CB 3.37Å; A60-A64 PolarHBondContact O-N 3.31Å; A60-T193 HydrophobicContact CB-CG2 3.72Å; A60-T196 HydrophobicContact CB-CG2 4.07Å; A60-T196 PolarHBondContact O-OG1 3.12Å; A60-T196 VanDerWaalsContact O-OG1 3.11Å
61	S	91.9	Very high	88.6	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-68.5	-35.3	178.7	-172.6	0	0	0	0	112.6	S57 V58 F63 S65 D192 R291	S57-S61 WeakPolarHBondContact O-CB 3.11Å; S57-S61 PolarHBondContact O-N 3.41Å; V58-S61 PolarHBondContact O-N 3.32Å; S61-F63 VanDerWaalsContact C-N 3.34Å; S61-S65 VanDerWaalsContact O-CB 3.27Å; S61-S65 WeakPolarHBondContact O-CB 3.46Å; S61-S65 PolarHBondContact O-N 3.05Å; S61-S65 PolarHBondContact O-OG 3.28Å; S61-D192 PolarHBondContact OG-OD2 3.42Å; S61-R291 WeakPolarHBondContact OG-CD 3.32Å; S61-R291 PolarHBondContact OG-NE 3.01Å
62	L	93.1	Very high	89.3	Confident	0 Å²	0	17.8 Å²	17.8	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-60.6	-43.9	169.7	-74.2	169.6	0	0	0	111.5	V58 G59 A60 N66 I288 R291 C308	V58-L62 HydrophobicContact CG1-CD1 3.91Å; V58-L62 HydrophobicContact CG1-CG 4.37Å; V58-L62 WeakPolarHBondContact O-CB 3.5Å; V58-L62 WeakPolarHBondContact O-CG 3.4Å; V58-L62 PolarHBondContact O-N 2.97Å; G59-L62 PolarHBondContact O-N 2.86Å; A60-L62 PolarHBondContact O-N 3.44Å; L62-N66 PolarHBondContact O-N 3.44Å; L62-I288 HydrophobicContact CD2-CG2 3.62Å; L62-I288 WeakPolarHBondContact CD2-O 3.28Å; L62-R291 HydrophobicContact CD2-CB 4.12Å; L62-C308 HydrophobicContact CB-CB 4Å; L62-C308 HydrophobicContact CD1-CB 4.28Å
63	F	93.3	Very high	89.6	Confident	4 Å²	4	14.5 Å²	14.5	2%	0.018	7%	0.065	C	C	.	.	H	α-helix	trans	-64.4	-53.2	176.1	176.2	-95.6	0	0	0	111.7	G59 A60 S61 S65 N66 I67 T196 I200 L311 K312 P315	G59-F63 PolarHBondContact O-N 3.35Å; A60-F63 WeakPolarHBondContact O-CB 3.38Å; A60-F63 PolarHBondContact O-N 3.29Å; S61-F63 VanDerWaalsContact C-N 3.34Å; F63-S65 VanDerWaalsContact C-N 3.28Å; F63-S65 PolarHBondContact O-N 3.27Å; F63-N66 PolarHBondContact O-N 3Å; F63-N66 VanDerWaalsContact O-N 3.09Å; F63-I67 HydrophobicContact CD1-CB 4.33Å; F63-I67 HydrophobicContact CD1-CG1 4.3Å; F63-I67 HydrophobicContact CD2-CG1 3.79Å; F63-I67 HydrophobicContact CE1-CB 4.02Å; F63-I67 HydrophobicContact CE1-CG1 4.02Å; F63-I67 HydrophobicContact CE1-CG2 4.15Å; F63-I67 HydrophobicContact CE2-CB 4.37Å; F63-I67 HydrophobicContact CE2-CD1 4.37Å; F63-I67 HydrophobicContact CE2-CG1 3.47Å; F63-I67 VanDerWaalsContact CE2-CG1 3.47Å; F63-I67 HydrophobicContact CG-CG1 4.22Å; F63-I67 HydrophobicContact CZ-CB 4.06Å; F63-I67 HydrophobicContact CZ-CG1 3.61Å; F63-I67 HydrophobicContact CZ-CG2 4.09Å; F63-I67 WeakPolarHBondContact O-CB 2.84Å; F63-I67 PolarHBondContact O-N 3.19Å; F63-T196 HydrophobicContact CD1-CG2 3.55Å; F63-T196 HydrophobicContact CE1-CG2 4.03Å; F63-T196 HydrophobicContact CG-CG2 4.47Å; F63-I200 HydrophobicContact CE1-CD1 4.11Å; F63-I200 HydrophobicContact CE1-CG1 4.1Å; F63-I200 HydrophobicContact CZ-CD1 4.47Å; F63-I200 HydrophobicContact CZ-CG1 4.34Å; F63-L311 HydrophobicContact CB-CB 4.38Å; F63-L311 HydrophobicContact CB-CD1 3.88Å; F63-L311 HydrophobicContact CD1-CD1 4.27Å; F63-L311 HydrophobicContact CD2-CB 3.41Å; F63-L311 VanDerWaalsContact CD2-CB 3.41Å; F63-L311 HydrophobicContact CD2-CD1 4.28Å; F63-L311 HydrophobicContact CD2-CG 4.48Å; F63-L311 HydrophobicContact CE2-CB 3.71Å; F63-L311 WeakPolarHBondContact CE2-O 3.39Å; F63-L311 HydrophobicContact CG-CB 3.92Å; F63-L311 HydrophobicContact CG-CD1 3.9Å; F63-L311 HydrophobicContact CZ-CB 4.45Å; F63-K312 HydrophobicContact CD2-CD 4.29Å; F63-P315 HydrophobicContact CE2-CG 4.36Å
64	A	90.2	Very high	89.8	Confident	0 Å²	0	14.4 Å²	14.4	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-61.1	-33	179.6	0	0	0	0	0	113.8	A60 N66 I67 D192 T196	A60-A64 WeakPolarHBondContact O-CB 3.37Å; A60-A64 PolarHBondContact O-N 3.31Å; A64-N66 PolarHBondContact O-N 3.43Å; A64-I67 CarbonylContact O-C 3.42Å; A64-D192 HydrophobicContact CB-CB 4Å; A64-T196 WeakPolarHBondContact CB-OG1 3.46Å
65	S	87.6	Confident	89.9	Confident	11 Å²	11	13.5 Å²	13.5	8%	0.077	6%	0.058	C	C	.	.	H	α-helix	trans	-67.6	-27.1	177.2	-62.3	0	0	0	0	113.4	S61 F63 R291	S61-S65 VanDerWaalsContact O-CB 3.27Å; S61-S65 WeakPolarHBondContact O-CB 3.46Å; S61-S65 PolarHBondContact O-N 3.05Å; S61-S65 PolarHBondContact O-OG 3.28Å; F63-S65 VanDerWaalsContact C-N 3.28Å; F63-S65 PolarHBondContact O-N 3.27Å; S65-R291 VanDerWaalsContact OG-CD 3.32Å; S65-R291 WeakPolarHBondContact OG-CD 3.43Å; S65-R291 PolarHBondContact OG-NE 2.82Å; S65-R291 PolarHBondContact OG-NH1 3.32Å; S65-R291 PolarHBondContact OG-NH2 3.44Å; S65-R291 VanDerWaalsContact OG-NH2 3.16Å
66	N	88.8	Confident	89.9	Confident	15 Å²	15	8.1 Å²	8.1	8%	0.08	4%	0.037	C	C	.	.	H	α-helix	trans	-90.3	-51.9	173.7	172.3	-85.8	0	0	0	110.5	L62 F63 A64 G68 H71 Y281 W282 K312	L62-N66 PolarHBondContact O-N 3.44Å; F63-N66 PolarHBondContact O-N 3Å; F63-N66 VanDerWaalsContact O-N 3.09Å; A64-N66 PolarHBondContact O-N 3.43Å; N66-G68 PolarHBondContact O-N 3.42Å; N66-H71 PolarHBondContact O-CE1 3.35Å; N66-H71 PolarHBondContact O-ND1 2.83Å; N66-H71 PolarHBondContact OD1-CE1 2.83Å; N66-H71 PolarHBondContact OD1-NE2 2.83Å; N66-Y281 VanDerWaalsContact CA-OH 3.27Å; N66-Y281 WeakPolarHBondContact CA-OH 3.39Å; N66-Y281 HydrophobicContact CB-CE1 4.15Å; N66-Y281 VanDerWaalsContact CB-OH 3.28Å; N66-Y281 WeakPolarHBondContact CB-OH 3.28Å; N66-Y281 VanDerWaalsContact ND2-CE1 3.3Å; N66-Y281 WeakPolarHBondContact ND2-CE1 3.35Å; N66-Y281 PolarHBondContact ND2-OH 3.07Å; N66-W282 HydrophobicContact CB-CH2 3.91Å; N66-W282 HydrophobicContact CB-CZ2 4.33Å; N66-K312 WeakPolarHBondContact OD1-CE 3.48Å; N66-K312 PolarHBondContact OD1-NZ 3.33Å
67	I	86.9	Confident	90	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.018	C	C	.	.	S	Bend	trans	-77.7	76.9	-179.1	-57.1	-59.4	0	0	0	110	F63 A64 H71 F72 P315 M319	F63-I67 HydrophobicContact CD1-CB 4.33Å; F63-I67 HydrophobicContact CD1-CG1 4.3Å; F63-I67 HydrophobicContact CD2-CG1 3.79Å; F63-I67 HydrophobicContact CE1-CB 4.02Å; F63-I67 HydrophobicContact CE1-CG1 4.02Å; F63-I67 HydrophobicContact CE1-CG2 4.15Å; F63-I67 HydrophobicContact CE2-CB 4.37Å; F63-I67 HydrophobicContact CE2-CD1 4.37Å; F63-I67 HydrophobicContact CE2-CG1 3.47Å; F63-I67 VanDerWaalsContact CE2-CG1 3.47Å; F63-I67 HydrophobicContact CG-CG1 4.22Å; F63-I67 HydrophobicContact CZ-CB 4.06Å; F63-I67 HydrophobicContact CZ-CG1 3.61Å; F63-I67 HydrophobicContact CZ-CG2 4.09Å; F63-I67 WeakPolarHBondContact O-CB 2.84Å; F63-I67 PolarHBondContact O-N 3.19Å; A64-I67 CarbonylContact O-C 3.42Å; I67-H71 HydrophobicContact CD1-CB 4.24Å; I67-F72 HydrophobicContact CG2-CE2 4.29Å; I67-P315 HydrophobicContact CD1-CG 3.83Å; I67-M319 HydrophobicContact CG2-CE 3.31Å; I67-M319 HydrophobicContact CG2-SD 4.5Å
68	G	80.2	Confident	90	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.018	C	C	.	.	S	Bend	trans	-99.6	-168.5	166.5	0	0	0	0	0	112.5	N66 G70 H71 F72 S384	N66-G68 PolarHBondContact O-N 3.42Å; G68-G70 PolarHBondContact O-N 2.6Å; G68-H71 PolarHBondContact O-N 3.26Å; G68-H71 VanDerWaalsContact O-N 3.09Å; G68-F72 PolarHBondContact O-N 3.31Å; G68-S384 WeakPolarHBondContact CA-OG 3.37Å
69	S	77.2	Confident	90.1	Very high	4 Å²	4	3 Å²	3	3%	0.028	2%	0.018	C	C	.	.	H	α-helix	trans	-57.5	-31.9	174.4	52.5	0	0	0	0	114.5	H71 F72 V73 D149 S152 L381	S69-H71 PolarHBondContact O-N 3.07Å; S69-F72 PolarHBondContact O-N 2.98Å; S69-F72 VanDerWaalsContact O-N 3.17Å; S69-V73 WeakPolarHBondContact O-CB 3.36Å; S69-V73 PolarHBondContact O-N 3.49Å; S69-D149 PolarHBondContact OG-O 2.9Å; S69-S152 WeakPolarHBondContact CB-OG 3.42Å; S69-S152 PolarHBondContact OG-OG 3.27Å; S69-L381 WeakPolarHBondContact OG-CD2 3.25Å
70	G	83.1	Confident	90.1	Very high	3 Å²	3	3.1 Å²	3.1	3%	0.031	2%	0.018	C	C	.	.	I	π-helix	trans	-56.9	-31	175.7	0	0	0	0	0	112.4	G68 G74 L75 S152	G68-G70 PolarHBondContact O-N 2.6Å; G70-G74 WeakPolarHBondContact O-CA 3.26Å; G70-G74 PolarHBondContact O-N 3.39Å; G70-L75 PolarHBondContact O-N 3.36Å; G70-S152 PolarHBondContact N-OG 2.75Å
71	H	90.9	Very high	90.1	Very high	22 Å²	22	4.2 Å²	4.2	10%	0.102	3%	0.027	C	C	.	.	I	π-helix	trans	-81.9	-44.4	175.5	-64.9	71.2	0	0	0	110.7	N66 I67 G68 S69 V73 L75 A76 E90 M319	N66-H71 PolarHBondContact O-CE1 3.35Å; N66-H71 PolarHBondContact O-ND1 2.83Å; N66-H71 PolarHBondContact OD1-CE1 2.83Å; N66-H71 PolarHBondContact OD1-NE2 2.83Å; I67-H71 HydrophobicContact CD1-CB 4.24Å; G68-H71 PolarHBondContact O-N 3.26Å; G68-H71 VanDerWaalsContact O-N 3.09Å; S69-H71 PolarHBondContact O-N 3.07Å; H71-V73 VanDerWaalsContact C-N 3.31Å; H71-V73 PolarHBondContact O-N 3.34Å; H71-L75 HydrophobicContact CB-CB 4.25Å; H71-L75 WeakPolarHBondContact O-CA 3.48Å; H71-L75 WeakPolarHBondContact O-CB 3.34Å; H71-L75 PolarHBondContact O-N 3.45Å; H71-A76 PolarHBondContact O-N 2.95Å; H71-E90 IonicContact CD2-OE1 2.69Å; H71-E90 PolarHBondContact CD2-OE1 3.21Å; H71-E90 VanDerWaalsContact CD2-OE1 3.23Å; H71-E90 IonicContact NE2-OE1 3.74Å; H71-E90 PolarHBondContact NE2-OE1 2.89Å; H71-M319 HydrophobicContact CB-SD 3.9Å
72	F	89.3	Confident	90.1	Very high	0 Å²	0	4.5 Å²	4.5	0%	0	3%	0.03	C	C	.	.	I	π-helix	trans	-60.4	-40.1	176.8	-77.6	-68.2	0	0	0	113.7	I67 G68 S69 A76 I199 M319 Y357 M373 M377	I67-F72 HydrophobicContact CG2-CE2 4.29Å; G68-F72 PolarHBondContact O-N 3.31Å; S69-F72 PolarHBondContact O-N 2.98Å; S69-F72 VanDerWaalsContact O-N 3.17Å; F72-A76 WeakPolarHBondContact O-CB 3.36Å; F72-I199 HydrophobicContact CE2-CG2 4.14Å; F72-I199 HydrophobicContact CZ-CG2 3.69Å; F72-M319 HydrophobicContact CD1-CE 3.82Å; F72-M319 HydrophobicContact CD1-CG 4.17Å; F72-M319 HydrophobicContact CD1-SD 4.13Å; F72-M319 HydrophobicContact CD2-CE 4.21Å; F72-M319 HydrophobicContact CE1-CE 3.35Å; F72-M319 HydrophobicContact CE1-CG 4.12Å; F72-M319 HydrophobicContact CE1-SD 4.19Å; F72-M319 HydrophobicContact CE2-CE 3.78Å; F72-M319 HydrophobicContact CG-CE 4.23Å; F72-M319 HydrophobicContact CZ-CE 3.32Å; F72-Y357 HydrophobicContact CB-CD1 4.26Å; F72-Y357 AromaticContact CD1-CD1 3.72Å; F72-Y357 HydrophobicContact CD1-CD1 3.72Å; F72-Y357 HydrophobicContact CD1-CD2 4.19Å; F72-Y357 AromaticContact CD1-CE1 3.3Å; F72-Y357 HydrophobicContact CD1-CE1 3.3Å; F72-Y357 AromaticContact CD1-CE2 3.82Å; F72-Y357 HydrophobicContact CD1-CE2 3.82Å; F72-Y357 HydrophobicContact CD1-CG 4.14Å; F72-Y357 AromaticContact CD1-CZ 3.36Å; F72-Y357 AromaticContact CE1-CE1 3.71Å; F72-Y357 HydrophobicContact CE1-CE1 3.71Å; F72-Y357 HydrophobicContact CE1-CE2 4.12Å; F72-Y357 AromaticContact CE1-CZ 3.45Å; F72-Y357 VanDerWaalsContact CE1-CZ 3.45Å; F72-Y357 WeakPolarHBondContact CE1-OH 3.26Å; F72-Y357 HydrophobicContact CG-CD1 4.39Å; F72-Y357 HydrophobicContact CG-CE1 4.26Å; F72-Y357 WeakPolarHBondContact O-CB 3.34Å; F72-M373 HydrophobicContact CE1-CE 4.2Å; F72-M373 HydrophobicContact CZ-CE 4.49Å; F72-M377 HydrophobicContact CB-CE 3.46Å; F72-M377 VanDerWaalsContact CB-CE 3.46Å; F72-M377 HydrophobicContact CD1-CE 3.98Å; F72-M377 HydrophobicContact CD2-CE 3.96Å; F72-M377 HydrophobicContact CG-CE 3.53Å
73	V	90.1	Very high	90.2	Very high	0 Å²	0	4.5 Å²	4.5	0%	0	3%	0.03	C	C	.	.	I	π-helix	trans	-89	-51.3	-178.6	173.2	0	0	0	0	110.3	S69 H71 G77 V155 N354 P358	S69-V73 WeakPolarHBondContact O-CB 3.36Å; S69-V73 PolarHBondContact O-N 3.49Å; H71-V73 VanDerWaalsContact C-N 3.31Å; H71-V73 PolarHBondContact O-N 3.34Å; V73-G77 WeakPolarHBondContact O-CA 3.49Å; V73-G77 PolarHBondContact O-N 3.31Å; V73-V155 HydrophobicContact CG1-CG1 4.34Å; V73-N354 HydrophobicContact CG1-CB 3.72Å; V73-N354 WeakPolarHBondContact CG1-O 3.48Å; V73-P358 HydrophobicContact CG2-CG 4.36Å
74	G	90.1	Very high	90.3	Very high	0 Å²	0	5.7 Å²	5.7	0%	0	4%	0.036	C	C	.	.	I	π-helix	trans	-77.5	-53.6	-175.2	0	0	0	0	0	113.6	G70 A76 G77 T78	G70-G74 WeakPolarHBondContact O-CA 3.26Å; G70-G74 PolarHBondContact O-N 3.39Å; G74-A76 PolarHBondContact O-N 2.87Å; G74-G77 PolarHBondContact O-N 3Å; G74-T78 PolarHBondContact O-N 3.35Å; G74-T78 PolarHBondContact O-OG1 2.87Å
75	L	93.3	Very high	90.5	Very high	0 Å²	0	5.7 Å²	5.7	0%	0	4%	0.036	C	C	.	.	I	π-helix	trans	-63.9	-44	-177.9	-173	74.5	0	0	0	111	G70 H71 G79 V86 E90 P315 M319 V320 F444	G70-L75 PolarHBondContact O-N 3.36Å; H71-L75 HydrophobicContact CB-CB 4.25Å; H71-L75 WeakPolarHBondContact O-CA 3.48Å; H71-L75 WeakPolarHBondContact O-CB 3.34Å; H71-L75 PolarHBondContact O-N 3.45Å; L75-G79 PolarHBondContact O-N 2.97Å; L75-V86 HydrophobicContact CD1-CB 4.23Å; L75-V86 HydrophobicContact CD1-CG1 3.87Å; L75-V86 HydrophobicContact CD1-CG2 3.56Å; L75-V86 HydrophobicContact CG-CG1 4.42Å; L75-E90 HydrophobicContact CD1-CG 4.44Å; L75-E90 HydrophobicContact CD2-CG 3.77Å; L75-P315 HydrophobicContact CD2-CB 3.99Å; L75-M319 HydrophobicContact CD2-CB 4.37Å; L75-M319 HydrophobicContact CD2-SD 4.37Å; L75-V320 HydrophobicContact CD1-CG2 4.41Å; L75-V320 HydrophobicContact CD2-CG2 4.07Å; L75-V320 HydrophobicContact CG-CG2 3.88Å; L75-F444 HydrophobicContact CB-CD2 4.39Å; L75-F444 HydrophobicContact CB-CE2 4.38Å; L75-F444 HydrophobicContact CD1-CE1 4.19Å; L75-F444 HydrophobicContact CD1-CE2 4.18Å; L75-F444 HydrophobicContact CD1-CZ 3.93Å
76	A	95.2	Very high	90.8	Very high	0 Å²	0	5.2 Å²	5.2	0%	0	3%	0.033	C	C	.	.	H	α-helix	trans	-67.8	-36.7	175	0	0	0	0	0	112.2	H71 F72 G74 G79 A80 M319 G323 Y357	H71-A76 PolarHBondContact O-N 2.95Å; F72-A76 WeakPolarHBondContact O-CB 3.36Å; G74-A76 PolarHBondContact O-N 2.87Å; A76-G79 CarbonylContact O-C 3.49Å; A76-G79 WeakPolarHBondContact O-CA 3.34Å; A76-G79 PolarHBondContact O-N 3.16Å; A76-A80 WeakPolarHBondContact O-CB 3.38Å; A76-A80 PolarHBondContact O-N 2.93Å; A76-M319 WeakPolarHBondContact CB-O 3.5Å; A76-G323 WeakPolarHBondContact O-CA 3.36Å; A76-Y357 HydrophobicContact CB-CD2 3.94Å; A76-Y357 HydrophobicContact CB-CG 4.28Å
77	G	93.8	Very high	91	Very high	0 Å²	0	4.5 Å²	4.5	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-65	-46.5	176.3	0	0	0	0	0	112.7	V73 G74 G79 A80 A81 S353	V73-G77 WeakPolarHBondContact O-CA 3.49Å; V73-G77 PolarHBondContact O-N 3.31Å; G74-G77 PolarHBondContact O-N 3Å; G77-G79 VanDerWaalsContact C-N 3.28Å; G77-G79 PolarHBondContact O-N 2.97Å; G77-A80 WeakPolarHBondContact O-CB 3.34Å; G77-A80 PolarHBondContact O-N 3.38Å; G77-A80 VanDerWaalsContact O-N 3.13Å; G77-A81 WeakPolarHBondContact O-CB 3.26Å; G77-A81 PolarHBondContact O-N 3.01Å; G77-S353 WeakPolarHBondContact CA-O 3.26Å; G77-S353 WeakPolarHBondContact O-CB 3.5Å
78	T	93.6	Very high	91.3	Very high	1 Å²	1	4.8 Å²	4.8	1%	0.006	3%	0.032	C	C	.	.	H	α-helix	trans	-63.8	-35.2	171.7	-62.2	0	0	0	0	111.1	G74 A81 A82 V86	G74-T78 PolarHBondContact O-N 3.35Å; G74-T78 PolarHBondContact O-OG1 2.87Å; T78-A81 PolarHBondContact O-N 3.05Å; T78-A82 WeakPolarHBondContact O-CB 3.32Å; T78-A82 PolarHBondContact O-N 3.47Å; T78-V86 HydrophobicContact CG2-CB 3.78Å; T78-V86 HydrophobicContact CG2-CG1 4.31Å; T78-V86 HydrophobicContact CG2-CG2 3.57Å
79	G	95.6	Very high	91.7	Very high	0 Å²	0	5.9 Å²	5.9	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-59.4	-44.5	169.8	0	0	0	0	0	112.9	L75 A76 G77 G83 M324	L75-G79 PolarHBondContact O-N 2.97Å; A76-G79 CarbonylContact O-C 3.49Å; A76-G79 WeakPolarHBondContact O-CA 3.34Å; A76-G79 PolarHBondContact O-N 3.16Å; G77-G79 VanDerWaalsContact C-N 3.28Å; G77-G79 PolarHBondContact O-N 2.97Å; G79-G83 VanDerWaalsContact O-CA 3.27Å; G79-G83 WeakPolarHBondContact O-CA 3.43Å; G79-G83 PolarHBondContact O-N 3.05Å; G79-M324 WeakPolarHBondContact O-CG 3.34Å
80	A	95.8	Very high	92.5	Very high	1 Å²	1	5.9 Å²	5.9	1%	0.008	4%	0.037	C	C	.	.	H	α-helix	trans	-62.3	-45.1	175.5	0	0	0	0	0	111.7	A76 G77 Y224 G323 R327 V334 A356	A76-A80 WeakPolarHBondContact O-CB 3.38Å; A76-A80 PolarHBondContact O-N 2.93Å; G77-A80 WeakPolarHBondContact O-CB 3.34Å; G77-A80 PolarHBondContact O-N 3.38Å; G77-A80 VanDerWaalsContact O-N 3.13Å; A80-Y224 PolarHBondContact O-OH 2.98Å; A80-G323 WeakPolarHBondContact CB-O 3.36Å; A80-R327 HydrophobicContact CB-CB 4.34Å; A80-R327 WeakPolarHBondContact O-CD 3.43Å; A80-R327 PolarHBondContact O-NH1 2.88Å; A80-R327 VanDerWaalsContact O-NH1 3.08Å; A80-V334 HydrophobicContact CB-CG1 3.94Å; A80-A356 HydrophobicContact CB-CB 3.76Å
81	A	92.4	Very high	92.9	Very high	27 Å²	27	9.9 Å²	9.9	22%	0.223	5%	0.051	C	C	.	.	H	α-helix	trans	-70.8	-47	-177.3	0	0	0	0	0	112.9	G77 T78 R327 Q442	G77-A81 WeakPolarHBondContact O-CB 3.26Å; G77-A81 PolarHBondContact O-N 3.01Å; T78-A81 PolarHBondContact O-N 3.05Å; A81-R327 PolarHBondContact O-NH1 3.04Å; A81-Q442 HydrophobicContact CB-CG 4.47Å
82	A	91.9	Very high	93	Very high	6 Å²	6	10.1 Å²	10.1	5%	0.05	5%	0.053	C	C	.	.	H	α-helix	trans	-121.3	-16.4	-164.2	0	0	0	0	0	114.7	T78 R258 D264	T78-A82 WeakPolarHBondContact O-CB 3.32Å; T78-A82 PolarHBondContact O-N 3.47Å; A82-R258 PolarHBondContact O-NH1 3.45Å; A82-R258 PolarHBondContact O-NH2 3.22Å; A82-D264 WeakPolarHBondContact CB-OD2 3.31Å
83	G	94.6	Very high	93.1	Very high	1 Å²	1	10.3 Å²	10.3	1%	0.01	5%	0.054	C	C	.	.			trans	95.9	-153	-179.9	0	0	0	0	0	114.8	G79 A85 Y224 A253	G79-G83 VanDerWaalsContact O-CA 3.27Å; G79-G83 WeakPolarHBondContact O-CA 3.43Å; G79-G83 PolarHBondContact O-N 3.05Å; G83-A85 PolarHBondContact O-N 3.37Å; G83-Y224 PolarHBondContact N-OH 3.01Å; G83-A253 CarbonylContact C-O 3.45Å; G83-A253 WeakPolarHBondContact CA-O 3.41Å
84	I	96.1	Very high	93.3	Very high	28 Å²	28	11.9 Å²	11.9	14%	0.144	6%	0.063	C	C	.	.	G	3₁₀ helix	trans	-77.4	-16.7	-162.1	77.5	175.2	0	0	0	114.9	V86 G87 A253 F254 M316 F321 M324	I84-V86 PolarHBondContact O-N 3.47Å; I84-V86 VanDerWaalsContact O-N 3.11Å; I84-G87 PolarHBondContact O-N 3.4Å; I84-A253 PolarHBondContact N-O 3.29Å; I84-F254 HydrophobicContact CD1-CB 4.49Å; I84-F254 WeakPolarHBondContact CD1-O 3.33Å; I84-F254 HydrophobicContact CG2-CD1 3.87Å; I84-F254 HydrophobicContact CG2-CE1 4.29Å; I84-M316 HydrophobicContact CB-SD 4.17Å; I84-M316 WeakPolarHBondContact O-CE 3.16Å; I84-F321 HydrophobicContact CG2-CD1 4.42Å; I84-F321 HydrophobicContact CG2-CE1 3.82Å; I84-M324 HydrophobicContact CG2-CE 4.28Å; I84-M324 HydrophobicContact CG2-SD 3.66Å
85	A	94.2	Very high	93.5	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.092	C	C	.	.	G	3₁₀ helix	trans	-56.9	-32.2	-174	0	0	0	0	0	113.3	G83 G87 G88 R258 L265	G83-A85 PolarHBondContact O-N 3.37Å; A85-G87 PolarHBondContact O-N 3Å; A85-G88 PolarHBondContact O-N 3.26Å; A85-R258 HydrophobicContact CB-CG 4.41Å; A85-L265 HydrophobicContact CB-CB 4.22Å; A85-L265 HydrophobicContact CB-CD1 3.89Å
86	V	93.5	Very high	93.6	Very high	2 Å²	2	19.1 Å²	19.1	1%	0.012	10%	0.095	C	C	.	.	G	3₁₀ helix	trans	-63.2	-27	178.9	76	0	0	0	0	112.9	L75 T78 I84 G88 F89 L265 V320 F444	L75-V86 HydrophobicContact CD1-CB 4.23Å; L75-V86 HydrophobicContact CD1-CG1 3.87Å; L75-V86 HydrophobicContact CD1-CG2 3.56Å; L75-V86 HydrophobicContact CG-CG1 4.42Å; T78-V86 HydrophobicContact CG2-CB 3.78Å; T78-V86 HydrophobicContact CG2-CG1 4.31Å; T78-V86 HydrophobicContact CG2-CG2 3.57Å; I84-V86 PolarHBondContact O-N 3.47Å; I84-V86 VanDerWaalsContact O-N 3.11Å; V86-G88 PolarHBondContact O-N 3.16Å; V86-G88 VanDerWaalsContact O-N 3.09Å; V86-F89 HydrophobicContact CG2-CD2 4.21Å; V86-F89 WeakPolarHBondContact O-CD2 3.33Å; V86-F89 PolarHBondContact O-N 3.42Å; V86-F89 VanDerWaalsContact O-N 3.12Å; V86-L265 HydrophobicContact CB-CD1 4.15Å; V86-V320 HydrophobicContact CG1-CG1 4.12Å; V86-V320 HydrophobicContact CG1-CG2 3.81Å; V86-F444 HydrophobicContact CG2-CD1 3.8Å; V86-F444 HydrophobicContact CG2-CE1 3.85Å
87	G	93.3	Very high	93.6	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.095	C	C	.	.	G	3₁₀ helix	trans	-66.5	-10	173.5	0	0	0	0	0	113.4	I84 A85 F89 E90 W91 M316	I84-G87 PolarHBondContact O-N 3.4Å; A85-G87 PolarHBondContact O-N 3Å; G87-F89 PolarHBondContact O-N 3.18Å; G87-E90 WeakPolarHBondContact O-CB 3.28Å; G87-E90 PolarHBondContact O-N 2.75Å; G87-E90 VanDerWaalsContact O-N 3.13Å; G87-W91 PolarHBondContact O-N 3.29Å; G87-W91 VanDerWaalsContact O-N 3.12Å; G87-M316 VanDerWaalsContact CA-CE 3.45Å
88	G	92.4	Very high	93.6	Very high	6 Å²	6	21.9 Å²	21.9	6%	0.062	11%	0.109	C	C	.	.	H	α-helix	trans	-58.1	-32.7	168.1	0	0	0	0	0	113.4	A85 V86 E90 N92	A85-G88 PolarHBondContact O-N 3.26Å; V86-G88 PolarHBondContact O-N 3.16Å; V86-G88 VanDerWaalsContact O-N 3.09Å; G88-E90 VanDerWaalsContact C-N 3.28Å; G88-E90 PolarHBondContact O-N 3.37Å; G88-N92 VanDerWaalsContact O-CB 3.22Å; G88-N92 WeakPolarHBondContact O-CB 3.29Å; G88-N92 PolarHBondContact O-N 3.37Å
89	F	90.4	Very high	93.6	Very high	23 Å²	23	24.5 Å²	24.5	10%	0.101	12%	0.123	C	C	.	.	H	α-helix	trans	-60.7	-39.7	174.1	-78.3	-89	0	0	0	111.8	V86 G87 A93 L265 M274 F444 Q448 L518	V86-F89 HydrophobicContact CG2-CD2 4.21Å; V86-F89 WeakPolarHBondContact O-CD2 3.33Å; V86-F89 PolarHBondContact O-N 3.42Å; V86-F89 VanDerWaalsContact O-N 3.12Å; G87-F89 PolarHBondContact O-N 3.18Å; F89-A93 PolarHBondContact O-N 3.44Å; F89-L265 HydrophobicContact CE2-CD1 4.4Å; F89-L265 HydrophobicContact CE2-CD2 3.88Å; F89-L265 HydrophobicContact CZ-CD2 4.4Å; F89-M274 WeakPolarHBondContact CA-SD 3.32Å; F89-M274 HydrophobicContact CB-SD 3.91Å; F89-M274 HydrophobicContact CD1-CG 3.95Å; F89-M274 HydrophobicContact CD1-SD 3.23Å; F89-M274 WeakPolarHBondContact CD1-SD 3.45Å; F89-M274 HydrophobicContact CD2-CE 4.13Å; F89-M274 HydrophobicContact CD2-SD 3.46Å; F89-M274 WeakPolarHBondContact CD2-SD 3.44Å; F89-M274 HydrophobicContact CE1-CG 3.67Å; F89-M274 HydrophobicContact CE1-SD 3.46Å; F89-M274 WeakPolarHBondContact CE1-SD 3.37Å; F89-M274 HydrophobicContact CE2-CE 4.23Å; F89-M274 HydrophobicContact CE2-SD 3.69Å; F89-M274 HydrophobicContact CG-CE 4.4Å; F89-M274 HydrophobicContact CG-CG 4.49Å; F89-M274 HydrophobicContact CG-SD 3.23Å; F89-M274 WeakPolarHBondContact CG-SD 3.35Å; F89-M274 HydrophobicContact CZ-CG 4Å; F89-M274 HydrophobicContact CZ-SD 3.68Å; F89-F444 HydrophobicContact CB-CE1 4.32Å; F89-F444 HydrophobicContact CB-CZ 4.24Å; F89-F444 HydrophobicContact CD1-CE1 4.22Å; F89-F444 HydrophobicContact CD1-CZ 4.49Å; F89-F444 AromaticContact CD2-CE1 3.69Å; F89-F444 HydrophobicContact CD2-CE1 3.69Å; F89-F444 HydrophobicContact CD2-CZ 4.43Å; F89-F444 HydrophobicContact CE1-CE1 4.49Å; F89-F444 AromaticContact CE2-CE1 3.98Å; F89-F444 HydrophobicContact CE2-CE1 3.98Å; F89-F444 AromaticContact CG-CE1 3.81Å; F89-F444 HydrophobicContact CG-CE1 3.81Å; F89-F444 HydrophobicContact CG-CZ 4.14Å; F89-F444 HydrophobicContact CZ-CE1 4.39Å; F89-Q448 HydrophobicContact CD1-CG 4.31Å; F89-Q448 HydrophobicContact CE1-CB 4.14Å; F89-Q448 VanDerWaalsContact CE1-CD 3.5Å; F89-Q448 HydrophobicContact CE1-CG 3.63Å; F89-Q448 HydrophobicContact CZ-CB 4.09Å; F89-Q448 HydrophobicContact CZ-CG 3.78Å; F89-L518 HydrophobicContact CZ-CD2 4.4Å
90	E	92.6	Very high	93.5	Very high	4 Å²	4	24.5 Å²	24.5	2%	0.019	12%	0.123	C	C	.	.	H	α-helix	trans	-74.6	-43.1	-177.1	-62.7	-61.6	133.3	0	0	111.8	H71 L75 G87 G88 A93 K312 P315	H71-E90 IonicContact CD2-OE1 2.69Å; H71-E90 PolarHBondContact CD2-OE1 3.21Å; H71-E90 VanDerWaalsContact CD2-OE1 3.23Å; H71-E90 IonicContact NE2-OE1 3.74Å; H71-E90 PolarHBondContact NE2-OE1 2.89Å; L75-E90 HydrophobicContact CD1-CG 4.44Å; L75-E90 HydrophobicContact CD2-CG 3.77Å; G87-E90 WeakPolarHBondContact O-CB 3.28Å; G87-E90 PolarHBondContact O-N 2.75Å; G87-E90 VanDerWaalsContact O-N 3.13Å; G88-E90 VanDerWaalsContact C-N 3.28Å; G88-E90 PolarHBondContact O-N 3.37Å; E90-A93 WeakPolarHBondContact O-CB 3.41Å; E90-A93 PolarHBondContact O-N 3.38Å; E90-K312 IonicContact OE1-NZ 3.9Å; E90-K312 PolarHBondContact OE1-NZ 3.33Å; E90-K312 WeakPolarHBondContact OE2-CD 3.31Å; E90-K312 IonicContact OE2-NZ 2.92Å; E90-K312 PolarHBondContact OE2-NZ 3.28Å; E90-P315 HydrophobicContact CG-CB 3.97Å; E90-P315 HydrophobicContact CG-CG 4.47Å
91	W	93.3	Very high	93.3	Very high	87 Å²	87	24.4 Å²	24.4	33%	0.33	12%	0.122	S	C	.	.	H	α-helix	trans	-74.1	-31.4	178.5	-68.3	-1	0	0	0	112.7	G87 A93 L94 L256 L313 M316 F317	G87-W91 PolarHBondContact O-N 3.29Å; G87-W91 VanDerWaalsContact O-N 3.12Å; W91-A93 VanDerWaalsContact C-N 3.31Å; W91-A93 PolarHBondContact O-N 2.94Å; W91-L94 WeakPolarHBondContact O-CB 3.25Å; W91-L94 PolarHBondContact O-N 3.28Å; W91-L256 HydrophobicContact CE3-CD2 3.95Å; W91-L256 HydrophobicContact CZ3-CD2 3.99Å; W91-L313 HydrophobicContact CG-CD2 4.36Å; W91-L313 PolarHBondContact NE1-O 3.49Å; W91-M316 HydrophobicContact CD2-CE 4.31Å; W91-M316 HydrophobicContact CE3-CE 4.44Å; W91-M316 HydrophobicContact CH2-CE 4.07Å; W91-M316 HydrophobicContact CZ2-CB 4.07Å; W91-M316 HydrophobicContact CZ2-CE 3.92Å; W91-M316 HydrophobicContact CZ2-CG 3.82Å; W91-M316 HydrophobicContact CZ3-CE 4.33Å; W91-F317 HydrophobicContact CZ2-CE2 4.39Å; W91-F317 HydrophobicContact CZ2-CZ 4.23Å
92	N	92.4	Very high	93.1	Very high	26 Å²	26	28.8 Å²	28.8	14%	0.139	13%	0.133	C	C	.	.	H	α-helix	trans	-63.1	-40.4	171.5	-168	-88.9	0	0	0	111	G88 L94 F95 T275	G88-N92 VanDerWaalsContact O-CB 3.22Å; G88-N92 WeakPolarHBondContact O-CB 3.29Å; G88-N92 PolarHBondContact O-N 3.37Å; N92-L94 PolarHBondContact O-N 3Å; N92-F95 PolarHBondContact O-N 3.44Å; N92-T275 PolarHBondContact ND2-OG1 3.46Å; N92-T275 WeakPolarHBondContact OD1-CA 3.44Å; N92-T275 PolarHBondContact OD1-OG1 2.75Å; N92-T275 VanDerWaalsContact OD1-OG1 3.09Å
93	A	91.8	Very high	92.9	Very high	5 Å²	5	29.7 Å²	29.7	4%	0.041	14%	0.137	C	C	.	.	H	α-helix	trans	-57.1	-33.7	179.7	0	0	0	0	0	113.4	F89 E90 W91 F95 I96 V97 W282	F89-A93 PolarHBondContact O-N 3.44Å; E90-A93 WeakPolarHBondContact O-CB 3.41Å; E90-A93 PolarHBondContact O-N 3.38Å; W91-A93 VanDerWaalsContact C-N 3.31Å; W91-A93 PolarHBondContact O-N 2.94Å; A93-F95 VanDerWaalsContact C-N 3.29Å; A93-F95 PolarHBondContact O-N 2.95Å; A93-I96 PolarHBondContact O-N 3.42Å; A93-I96 VanDerWaalsContact O-N 3.11Å; A93-V97 WeakPolarHBondContact O-CG2 3.31Å; A93-V97 PolarHBondContact O-N 3.44Å; A93-W282 HydrophobicContact CB-CZ2 3.88Å
94	L	93.7	Very high	92.7	Very high	33 Å²	33	29.6 Å²	29.6	17%	0.173	14%	0.136	C	C	.	.	H	α-helix	trans	-49.4	-50.4	176.2	166.9	63.8	0	0	0	111.8	W91 N92 I96 L98 G309 L313	W91-L94 WeakPolarHBondContact O-CB 3.25Å; W91-L94 PolarHBondContact O-N 3.28Å; N92-L94 PolarHBondContact O-N 3Å; L94-I96 VanDerWaalsContact C-N 3.33Å; L94-I96 PolarHBondContact O-N 3.08Å; L94-L98 WeakPolarHBondContact O-CG 3.41Å; L94-L98 PolarHBondContact O-N 3.29Å; L94-G309 VanDerWaalsContact CD1-C 3.42Å; L94-G309 VanDerWaalsContact CD1-CA 3.43Å; L94-G309 WeakPolarHBondContact CD1-O 3.2Å; L94-L313 HydrophobicContact CD2-CD2 4.01Å
95	F	93.2	Very high	92.4	Very high	141 Å²	141	28.3 Å²	28.3	62%	0.618	13%	0.13	S	C	*	.	H	α-helix	trans	-68.1	-36.2	-177.2	-60	-72.7	0	0	0	111.8	N92 A93 L98 L99	N92-F95 PolarHBondContact O-N 3.44Å; A93-F95 VanDerWaalsContact C-N 3.29Å; A93-F95 PolarHBondContact O-N 2.95Å; F95-L98 PolarHBondContact O-N 2.95Å; F95-L99 PolarHBondContact O-N 2.81Å
96	I	95.5	Very high	92	Very high	10 Å²	10	29.8 Å²	29.8	5%	0.051	14%	0.139	C	C	.	.	H	α-helix	trans	-77.1	-32.8	-177.6	-45.2	-54.5	0	0	0	112.1	A93 L94 L98 L99 L100 T275 G278 I279 W282	A93-I96 PolarHBondContact O-N 3.42Å; A93-I96 VanDerWaalsContact O-N 3.11Å; L94-I96 VanDerWaalsContact C-N 3.33Å; L94-I96 PolarHBondContact O-N 3.08Å; I96-L98 VanDerWaalsContact C-N 3.28Å; I96-L98 PolarHBondContact O-N 2.89Å; I96-L99 CarbonylContact O-C 3.51Å; I96-L99 WeakPolarHBondContact O-CA 3.28Å; I96-L99 VanDerWaalsContact O-CB 3.32Å; I96-L99 WeakPolarHBondContact O-CB 3.23Å; I96-L99 PolarHBondContact O-N 2.77Å; I96-L99 VanDerWaalsContact O-N 3.15Å; I96-L100 PolarHBondContact O-N 2.95Å; I96-T275 HydrophobicContact CD1-CG2 3.82Å; I96-G278 WeakPolarHBondContact CG2-O 3.47Å; I96-I279 HydrophobicContact CG2-CG1 4.23Å; I96-W282 HydrophobicContact CB-CG 4.44Å; I96-W282 HydrophobicContact CG2-CB 3.91Å; I96-W282 HydrophobicContact CG2-CG 4.31Å
97	V	95.1	Very high	91.6	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-62.5	-38.1	172.4	175.6	0	0	0	0	110.8	A93 L100 G101 W282 C305 C308	A93-V97 WeakPolarHBondContact O-CG2 3.31Å; A93-V97 PolarHBondContact O-N 3.44Å; V97-L100 WeakPolarHBondContact O-CB 3.13Å; V97-L100 PolarHBondContact O-N 3.43Å; V97-G101 PolarHBondContact O-N 2.8Å; V97-W282 HydrophobicContact CG2-CD2 3.45Å; V97-W282 VanDerWaalsContact CG2-CD2 3.45Å; V97-W282 HydrophobicContact CG2-CE3 3.38Å; V97-W282 HydrophobicContact CG2-CG 4.14Å; V97-W282 HydrophobicContact CG2-CH2 3.84Å; V97-W282 HydrophobicContact CG2-CZ2 3.91Å; V97-W282 HydrophobicContact CG2-CZ3 3.57Å; V97-C305 HydrophobicContact CG1-CB 3.89Å; V97-C305 VanDerWaalsContact CG1-O 3.23Å; V97-C305 WeakPolarHBondContact CG1-O 3.47Å; V97-C308 HydrophobicContact CG1-CB 4.04Å
98	L	94.2	Very high	91.3	Very high	58 Å²	58	31.6 Å²	31.6	30%	0.304	15%	0.15	S	C	.	.	H	α-helix	trans	-67.6	-40.3	173.1	-63.8	177.9	0	0	0	111.4	L94 F95 I96 L100 G101 W102 I306	L94-L98 WeakPolarHBondContact O-CG 3.41Å; L94-L98 PolarHBondContact O-N 3.29Å; F95-L98 PolarHBondContact O-N 2.95Å; I96-L98 VanDerWaalsContact C-N 3.28Å; I96-L98 PolarHBondContact O-N 2.89Å; L98-L100 VanDerWaalsContact C-N 3.31Å; L98-L100 PolarHBondContact O-N 3.49Å; L98-G101 PolarHBondContact O-N 2.8Å; L98-W102 HydrophobicContact CD2-CZ3 4.02Å; L98-W102 PolarHBondContact O-N 3.23Å; L98-W102 VanDerWaalsContact O-N 3.08Å; L98-I306 HydrophobicContact CD2-CG1 3.94Å
99	L	93.1	Very high	90.8	Very high	56 Å²	56	33.7 Å²	33.7	29%	0.293	16%	0.16	S	C	.	.	H	α-helix	trans	-58.2	-43	173.5	-175.3	67.2	0	0	0	111.6	F95 I96 G101 L103 F104 I279	F95-L99 PolarHBondContact O-N 2.81Å; I96-L99 CarbonylContact O-C 3.51Å; I96-L99 WeakPolarHBondContact O-CA 3.28Å; I96-L99 VanDerWaalsContact O-CB 3.32Å; I96-L99 WeakPolarHBondContact O-CB 3.23Å; I96-L99 PolarHBondContact O-N 2.77Å; I96-L99 VanDerWaalsContact O-N 3.15Å; L99-G101 PolarHBondContact O-N 3.28Å; L99-L103 HydrophobicContact CD1-CB 3.99Å; L99-L103 HydrophobicContact CD1-CD2 3.64Å; L99-L103 HydrophobicContact CD1-CG 4.49Å; L99-L103 HydrophobicContact CG-CD2 4.31Å; L99-L103 VanDerWaalsContact O-CB 3.26Å; L99-L103 WeakPolarHBondContact O-CB 3.5Å; L99-L103 PolarHBondContact O-N 3.05Å; L99-F104 HydrophobicContact CD2-CE2 3.96Å; L99-F104 HydrophobicContact CG-CD2 4.18Å; L99-F104 HydrophobicContact CG-CE2 3.96Å; L99-I279 HydrophobicContact CD2-CG1 4.25Å
100	L	94.5	Very high	90.1	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.177	C	C	.	.	I	π-helix	trans	-54.2	-54.4	174.2	166.2	66.5	0	0	0	111.1	I96 V97 L98 W102 F104 V105 W282 I288 V289	I96-L100 PolarHBondContact O-N 2.95Å; V97-L100 WeakPolarHBondContact O-CB 3.13Å; V97-L100 PolarHBondContact O-N 3.43Å; L98-L100 VanDerWaalsContact C-N 3.31Å; L98-L100 PolarHBondContact O-N 3.49Å; L100-W102 PolarHBondContact O-N 3.41Å; L100-F104 HydrophobicContact CD1-CB 4.29Å; L100-F104 PolarHBondContact O-N 3.49Å; L100-V105 HydrophobicContact CD1-CG2 3.44Å; L100-V105 VanDerWaalsContact CD1-CG2 3.44Å; L100-V105 HydrophobicContact CG-CG2 3.83Å; L100-V105 WeakPolarHBondContact O-CG2 3.32Å; L100-V105 PolarHBondContact O-N 3.43Å; L100-W282 WeakPolarHBondContact CD1-O 3.27Å; L100-W282 WeakPolarHBondContact CD2-O 3.3Å; L100-I288 HydrophobicContact CD2-CG2 3.92Å; L100-V289 HydrophobicContact CD1-CG2 4.12Å
101	G	91.2	Very high	89.5	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	18%	0.183	C	C	.	.	I	π-helix	trans	-67.1	-33.5	-174.7	0	0	0	0	0	114.8	V97 L98 L99 C305	V97-G101 PolarHBondContact O-N 2.8Å; L98-G101 PolarHBondContact O-N 2.8Å; L99-G101 PolarHBondContact O-N 3.28Å; G101-C305 VanDerWaalsContact CA-SG 3.58Å
102	W	89.3	Confident	88.9	Confident	118 Å²	118	35 Å²	35	45%	0.447	19%	0.191	S	C	.	.	I	π-helix	trans	-95	-28.2	-175.9	-90.8	-107.1	0	0	0	114.6	L98 L100 K302 I306	L98-W102 HydrophobicContact CD2-CZ3 4.02Å; L98-W102 PolarHBondContact O-N 3.23Å; L98-W102 VanDerWaalsContact O-N 3.08Å; L100-W102 PolarHBondContact O-N 3.41Å; W102-K302 HydrophobicContact CD2-CD 4.27Å; W102-K302 HydrophobicContact CD2-CG 4.13Å; W102-K302 HydrophobicContact CE3-CB 4.4Å; W102-K302 HydrophobicContact CE3-CG 4.07Å; W102-K302 HydrophobicContact CH2-CB 3.63Å; W102-K302 HydrophobicContact CH2-CD 4.45Å; W102-K302 HydrophobicContact CH2-CG 4.06Å; W102-K302 HydrophobicContact CZ2-CB 4.04Å; W102-K302 HydrophobicContact CZ2-CD 4.04Å; W102-K302 HydrophobicContact CZ2-CG 4.14Å; W102-K302 HydrophobicContact CZ3-CB 3.85Å; W102-K302 HydrophobicContact CZ3-CG 4.04Å; W102-I306 HydrophobicContact CH2-CD1 3.59Å; W102-I306 HydrophobicContact CH2-CG1 3.73Å; W102-I306 HydrophobicContact CZ2-CD1 4.43Å; W102-I306 HydrophobicContact CZ3-CD1 4.46Å; W102-I306 HydrophobicContact CZ3-CG1 4.12Å
103	L	87.8	Confident	88.4	Confident	25 Å²	25	34 Å²	34	13%	0.131	19%	0.186	C	C	.	.	I	π-helix	trans	-110.8	-58.3	-174.7	-176.6	69.7	0	0	0	111.9	L99 V107 V466 F467 W554	L99-L103 HydrophobicContact CD1-CB 3.99Å; L99-L103 HydrophobicContact CD1-CD2 3.64Å; L99-L103 HydrophobicContact CD1-CG 4.49Å; L99-L103 HydrophobicContact CG-CD2 4.31Å; L99-L103 VanDerWaalsContact O-CB 3.26Å; L99-L103 WeakPolarHBondContact O-CB 3.5Å; L99-L103 PolarHBondContact O-N 3.05Å; L103-V107 WeakPolarHBondContact O-CG2 3.48Å; L103-V466 HydrophobicContact CD1-CG1 4.18Å; L103-V466 HydrophobicContact CD2-CG1 4.45Å; L103-V466 HydrophobicContact CG-CG1 4.22Å; L103-F467 HydrophobicContact CD1-CE1 4.39Å; L103-F467 HydrophobicContact CD1-CZ 4.08Å; L103-F467 HydrophobicContact CD2-CE1 4.4Å; L103-F467 HydrophobicContact CD2-CE2 3.6Å; L103-F467 HydrophobicContact CD2-CZ 3.35Å; L103-F467 HydrophobicContact CG-CZ 4.34Å; L103-W554 HydrophobicContact CD1-CZ2 4.18Å
104	F	89.3	Confident	87.9	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	19%	0.192	C	C	.	.	I	π-helix	trans	-79.4	-47.6	-168	-74.9	-88.7	0	0	0	113.2	L99 L100 V107 Y108 I279 C283 L463 V466	L99-F104 HydrophobicContact CD2-CE2 3.96Å; L99-F104 HydrophobicContact CG-CD2 4.18Å; L99-F104 HydrophobicContact CG-CE2 3.96Å; L100-F104 HydrophobicContact CD1-CB 4.29Å; L100-F104 PolarHBondContact O-N 3.49Å; F104-V107 WeakPolarHBondContact O-CB 3.45Å; F104-V107 PolarHBondContact O-N 2.92Å; F104-V107 VanDerWaalsContact O-N 3.09Å; F104-Y108 HydrophobicContact CB-CD2 4.39Å; F104-Y108 HydrophobicContact CB-CE2 3.76Å; F104-Y108 HydrophobicContact CD1-CE1 4.49Å; F104-Y108 HydrophobicContact CD1-CE2 4.38Å; F104-Y108 AromaticContact CD1-CZ 3.82Å; F104-Y108 VanDerWaalsContact CD1-OH 3.25Å; F104-Y108 WeakPolarHBondContact CD1-OH 3.41Å; F104-Y108 WeakPolarHBondContact O-CD2 3.43Å; F104-Y108 VanDerWaalsContact O-CG 3.3Å; F104-Y108 PolarHBondContact O-N 3.23Å; F104-I279 HydrophobicContact CZ-CG2 4.35Å; F104-C283 HydrophobicContact CB-CB 4.29Å; F104-C283 HydrophobicContact CD1-CB 3.92Å; F104-C283 HydrophobicContact CD2-CB 3.54Å; F104-C283 WeakPolarHBondContact CD2-SG 3.25Å; F104-C283 HydrophobicContact CE1-CB 4.03Å; F104-C283 HydrophobicContact CE2-CB 3.67Å; F104-C283 VanDerWaalsContact CE2-SG 3.58Å; F104-C283 HydrophobicContact CG-CB 3.65Å; F104-C283 HydrophobicContact CZ-CB 3.91Å; F104-L463 HydrophobicContact CZ-CD1 4.09Å; F104-V466 HydrophobicContact CD1-CG2 4.03Å; F104-V466 HydrophobicContact CE1-CG2 3.88Å
105	V	88.9	Confident	87.7	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-61	-42.7	-177.8	178.7	0	0	0	0	113.4	L100 V107 Y108 L109 C292 L298 V301	L100-V105 HydrophobicContact CD1-CG2 3.44Å; L100-V105 VanDerWaalsContact CD1-CG2 3.44Å; L100-V105 HydrophobicContact CG-CG2 3.83Å; L100-V105 WeakPolarHBondContact O-CG2 3.32Å; L100-V105 PolarHBondContact O-N 3.43Å; V105-V107 PolarHBondContact O-N 3.45Å; V105-Y108 PolarHBondContact O-N 3.04Å; V105-Y108 VanDerWaalsContact O-N 3.17Å; V105-L109 HydrophobicContact CG1-CD1 3.69Å; V105-L109 HydrophobicContact CG1-CG 3.92Å; V105-L109 WeakPolarHBondContact O-CB 3.35Å; V105-L109 WeakPolarHBondContact O-CG 3.44Å; V105-L109 PolarHBondContact O-N 3.37Å; V105-C292 HydrophobicContact CG1-CB 4.27Å; V105-C292 HydrophobicContact CG2-CB 3.63Å; V105-L298 HydrophobicContact CG1-CD1 4.45Å; V105-V301 HydrophobicContact CB-CG1 3.87Å; V105-V301 HydrophobicContact CG1-CB 4.27Å; V105-V301 HydrophobicContact CG1-CG1 3.55Å; V105-V301 HydrophobicContact CG1-CG2 3.98Å; V105-V301 HydrophobicContact CG2-CG1 3.87Å
106	P	86.4	Confident	87.6	Confident	32 Å²	32	27.2 Å²	27.2	21%	0.208	16%	0.155	C	C	.	.	H	α-helix	trans	-54.9	-40.1	173.4	-23	29.4	0	0	0	113	T110 L298	P106-T110 WeakPolarHBondContact O-CB 3.48Å; P106-T110 VanDerWaalsContact O-CG2 3.26Å; P106-T110 WeakPolarHBondContact O-CG2 3.38Å; P106-T110 PolarHBondContact O-N 2.94Å; P106-T110 VanDerWaalsContact O-N 3.16Å; P106-T110 PolarHBondContact O-OG1 2.89Å; P106-L298 HydrophobicContact CB-CD1 4.38Å; P106-L298 HydrophobicContact CB-CD2 4.34Å; P106-L298 HydrophobicContact CG-CD1 3.85Å; P106-L298 HydrophobicContact CG-CD2 4.21Å
107	V	85.2	Confident	87.4	Confident	39 Å²	39	26.9 Å²	26.9	24%	0.236	15%	0.153	C	C	.	.	H	α-helix	trans	-67	-43	178.1	175.5	0	0	0	0	110.8	L103 F104 V105 T110 A111 Y119	L103-V107 WeakPolarHBondContact O-CG2 3.48Å; F104-V107 WeakPolarHBondContact O-CB 3.45Å; F104-V107 PolarHBondContact O-N 2.92Å; F104-V107 VanDerWaalsContact O-N 3.09Å; V105-V107 PolarHBondContact O-N 3.45Å; V107-T110 PolarHBondContact O-OG1 2.85Å; V107-A111 WeakPolarHBondContact O-CB 3.38Å; V107-A111 PolarHBondContact O-N 3.29Å; V107-Y119 HydrophobicContact CG1-CE2 3.59Å
108	Y	87.2	Confident	87.1	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-69.5	-42.2	180	-56.8	-30.2	0	0	0	113.3	F104 V105 T110 A111 G112 M116 Y119 C283 V289 F462	F104-Y108 HydrophobicContact CB-CD2 4.39Å; F104-Y108 HydrophobicContact CB-CE2 3.76Å; F104-Y108 HydrophobicContact CD1-CE1 4.49Å; F104-Y108 HydrophobicContact CD1-CE2 4.38Å; F104-Y108 AromaticContact CD1-CZ 3.82Å; F104-Y108 VanDerWaalsContact CD1-OH 3.25Å; F104-Y108 WeakPolarHBondContact CD1-OH 3.41Å; F104-Y108 WeakPolarHBondContact O-CD2 3.43Å; F104-Y108 VanDerWaalsContact O-CG 3.3Å; F104-Y108 PolarHBondContact O-N 3.23Å; V105-Y108 PolarHBondContact O-N 3.04Å; V105-Y108 VanDerWaalsContact O-N 3.17Å; Y108-T110 VanDerWaalsContact C-N 3.34Å; Y108-T110 PolarHBondContact O-N 3.26Å; Y108-A111 PolarHBondContact O-N 3.18Å; Y108-G112 PolarHBondContact O-N 3.21Å; Y108-G112 VanDerWaalsContact O-N 3.14Å; Y108-M116 HydrophobicContact CD2-CE 4.33Å; Y108-M116 HydrophobicContact CD2-SD 3.98Å; Y108-M116 HydrophobicContact CE1-SD 4.31Å; Y108-M116 HydrophobicContact CE2-SD 3.67Å; Y108-M116 HydrophobicContact CG-SD 4.39Å; Y108-Y119 HydrophobicContact CD1-CD1 4.18Å; Y108-Y119 AromaticContact CD1-CD2 3.9Å; Y108-Y119 HydrophobicContact CD1-CD2 3.9Å; Y108-Y119 HydrophobicContact CD1-CE1 4.47Å; Y108-Y119 HydrophobicContact CD1-CE2 4.21Å; Y108-Y119 AromaticContact CD1-CG 3.89Å; Y108-Y119 HydrophobicContact CD1-CG 3.89Å; Y108-Y119 AromaticContact CE1-CD1 3.68Å; Y108-Y119 HydrophobicContact CE1-CD1 3.68Å; Y108-Y119 HydrophobicContact CE1-CD2 4.2Å; Y108-Y119 AromaticContact CE1-CE1 3.84Å; Y108-Y119 HydrophobicContact CE1-CE1 3.84Å; Y108-Y119 HydrophobicContact CE1-CE2 4.35Å; Y108-Y119 AromaticContact CE1-CG 3.87Å; Y108-Y119 HydrophobicContact CE1-CG 3.87Å; Y108-C283 WeakPolarHBondContact CE2-O 3.31Å; Y108-C283 PolarHBondContact OH-O 3.36Å; Y108-V289 HydrophobicContact CD2-CG1 3.49Å; Y108-V289 VanDerWaalsContact CD2-CG1 3.49Å; Y108-V289 HydrophobicContact CE2-CG1 3.76Å; Y108-V289 HydrophobicContact CE2-CG2 4.13Å; Y108-F462 HydrophobicContact CE1-CE1 4.49Å; Y108-F462 VanDerWaalsContact OH-CD1 3.3Å; Y108-F462 WeakPolarHBondContact OH-CD1 3.44Å
109	L	81.4	Confident	86.9	Confident	50 Å²	50	26.7 Å²	26.7	26%	0.262	15%	0.151	S	C	.	.	H	α-helix	trans	-62.7	-42.1	177.5	-75.5	174.3	0	0	0	111.6	V105 G112 L293 L298 V301	V105-L109 HydrophobicContact CG1-CD1 3.69Å; V105-L109 HydrophobicContact CG1-CG 3.92Å; V105-L109 WeakPolarHBondContact O-CB 3.35Å; V105-L109 WeakPolarHBondContact O-CG 3.44Å; V105-L109 PolarHBondContact O-N 3.37Å; L109-G112 PolarHBondContact O-N 3.06Å; L109-G112 VanDerWaalsContact O-N 3.1Å; L109-L293 HydrophobicContact CD2-CD2 3.57Å; L109-L293 HydrophobicContact CG-CD2 3.87Å; L109-L298 HydrophobicContact CD1-CD1 4.12Å; L109-V301 HydrophobicContact CD1-CG2 4.44Å
110	T	76.7	Confident	86.8	Confident	76 Å²	76	24 Å²	24	47%	0.466	14%	0.137	S	C	.	.	H	α-helix	trans	-70.6	-31.2	177.2	54.2	0	0	0	0	112.8	P106 V107 Y108 G112	P106-T110 WeakPolarHBondContact O-CB 3.48Å; P106-T110 VanDerWaalsContact O-CG2 3.26Å; P106-T110 WeakPolarHBondContact O-CG2 3.38Å; P106-T110 PolarHBondContact O-N 2.94Å; P106-T110 VanDerWaalsContact O-N 3.16Å; P106-T110 PolarHBondContact O-OG1 2.89Å; V107-T110 PolarHBondContact O-OG1 2.85Å; Y108-T110 VanDerWaalsContact C-N 3.34Å; Y108-T110 PolarHBondContact O-N 3.26Å; T110-G112 PolarHBondContact O-N 3.15Å
111	A	79.8	Confident	86.5	Confident	17 Å²	17	28.4 Å²	28.4	14%	0.14	16%	0.156	C	C	.	.	H	α-helix	trans	-68.2	-17.1	170.6	0	0	0	0	0	112.7	V107 Y108 V113 Y119 K122	V107-A111 WeakPolarHBondContact O-CB 3.38Å; V107-A111 PolarHBondContact O-N 3.29Å; Y108-A111 PolarHBondContact O-N 3.18Å; A111-V113 HydrophobicContact CB-CG1 3.92Å; A111-V113 HydrophobicContact CB-CG2 4.36Å; A111-V113 PolarHBondContact O-N 3.43Å; A111-Y119 HydrophobicContact CB-CD2 4.1Å; A111-K122 PolarHBondContact O-NZ 2.84Å
112	G	79.5	Confident	86.2	Confident	48 Å²	48	34.2 Å²	34.2	50%	0.495	18%	0.181	S	C	.	.	T	Hydrogen-bonded Turn	trans	65.7	28	178.6	0	0	0	0	0	113	Y108 L109 T110	Y108-G112 PolarHBondContact O-N 3.21Å; Y108-G112 VanDerWaalsContact O-N 3.14Å; L109-G112 PolarHBondContact O-N 3.06Å; L109-G112 VanDerWaalsContact O-N 3.1Å; T110-G112 PolarHBondContact O-N 3.15Å
113	V	83.3	Confident	86	Confident	7 Å²	7	29.3 Å²	29.3	4%	0.042	16%	0.163	C	C	.	.			trans	-88.5	156.1	-176	-64.6	0	0	0	0	111.7	A111 Q118	A111-V113 HydrophobicContact CB-CG1 3.92Å; A111-V113 HydrophobicContact CB-CG2 4.36Å; A111-V113 PolarHBondContact O-N 3.43Å; V113-Q118 HydrophobicContact CB-CB 4.28Å; V113-Q118 HydrophobicContact CG1-CB 4.19Å
114	I	81.3	Confident	85.9	Confident	31 Å²	31	28.6 Å²	28.6	16%	0.159	16%	0.158	C	C	.	.	S	Bend	trans	-105.8	-34.7	173.8	-52.3	-174.3	0	0	0	109.8	L48 Q118 Q286 T394 M398	L48-I114 HydrophobicContact CD1-CD1 4.18Å; L48-I114 HydrophobicContact CD1-CG1 4.03Å; L48-I114 HydrophobicContact CD1-CG2 4.15Å; L48-I114 HydrophobicContact CD2-CG2 4.21Å; L48-I114 HydrophobicContact CG-CG2 4.15Å; I114-Q118 VanDerWaalsContact N-OE1 3.16Å; I114-Q286 PolarHBondContact O-NE2 2.63Å; I114-T394 HydrophobicContact CG2-CG2 4.4Å; I114-M398 HydrophobicContact CD1-CE 4.14Å
115	T	89.9	Confident	85.3	Confident	0 Å²	0	30.4 Å²	30.4	0%	0	18%	0.177	C	C	.	.	S	Bend	trans	-117.3	151.3	179.8	76.7	0	0	0	0	113.2	Q118 Y119 Q286 T394 M398 D399	T115-Q118 WeakPolarHBondContact O-CB 3.49Å; T115-Q118 PolarHBondContact O-N 3.43Å; T115-Q118 WeakPolarHBondContact OG1-CB 3.47Å; T115-Q118 VanDerWaalsContact OG1-CD 3.26Å; T115-Q118 WeakPolarHBondContact OG1-CG 3.37Å; T115-Q118 PolarHBondContact OG1-N 3.09Å; T115-Y119 PolarHBondContact O-N 3.23Å; T115-Q286 VanDerWaalsContact CA-OE1 3.27Å; T115-T394 HydrophobicContact CG2-CG2 3.97Å; T115-M398 HydrophobicContact CG2-CB 4.1Å; T115-D399 VanDerWaalsContact CB-OD2 3.28Å; T115-D399 WeakPolarHBondContact CB-OD2 3.43Å; T115-D399 WeakPolarHBondContact CG2-OD2 3.45Å; T115-D399 PolarHBondContact OG1-OD1 2.81Å; T115-D399 VanDerWaalsContact OG1-OD1 3.13Å; T115-D399 PolarHBondContact OG1-OD2 2.85Å
116	M	91.2	Very high	84.7	Confident	4 Å²	4	31 Å²	31	2%	0.02	18%	0.184	C	C	.	.	H	α-helix	trans	-65.8	-38.2	177.3	-59.4	-55.3	107.8	0	0	112.6	Y108 Q118 Y119 L120 S284 V289 L293 F462	Y108-M116 HydrophobicContact CD2-CE 4.33Å; Y108-M116 HydrophobicContact CD2-SD 3.98Å; Y108-M116 HydrophobicContact CE1-SD 4.31Å; Y108-M116 HydrophobicContact CE2-SD 3.67Å; Y108-M116 HydrophobicContact CG-SD 4.39Å; M116-Q118 VanDerWaalsContact C-N 3.33Å; M116-Q118 PolarHBondContact O-N 3.41Å; M116-Y119 WeakPolarHBondContact O-CB 3.32Å; M116-Y119 PolarHBondContact O-N 3.42Å; M116-L120 PolarHBondContact O-N 2.93Å; M116-S284 VanDerWaalsContact CG-O 3.31Å; M116-S284 WeakPolarHBondContact CG-O 3.37Å; M116-V289 HydrophobicContact CE-CB 3.83Å; M116-V289 HydrophobicContact CE-CG1 3.26Å; M116-V289 HydrophobicContact CG-CB 4.42Å; M116-V289 HydrophobicContact SD-CB 3.87Å; M116-V289 HydrophobicContact SD-CG1 3.58Å; M116-V289 VanDerWaalsContact SD-CG1 3.58Å; M116-V289 HydrophobicContact SD-CG2 4.01Å; M116-L293 HydrophobicContact CE-CD1 3.91Å; M116-F462 HydrophobicContact CB-CE1 4.06Å; M116-F462 HydrophobicContact CB-CZ 3.77Å
117	P	91.3	Very high	84.4	Confident	3 Å²	3	31.8 Å²	31.8	2%	0.019	19%	0.193	C	C	.	.	H	α-helix	trans	-59.3	-38.9	168.9	-27.2	37.4	0	0	0	113.6	Y119 L120 K121 S130 L133 S134 L395	P117-Y119 VanDerWaalsContact C-N 3.28Å; P117-Y119 PolarHBondContact O-N 3.49Å; P117-L120 PolarHBondContact O-N 3.26Å; P117-K121 PolarHBondContact O-N 3.34Å; P117-S130 WeakPolarHBondContact CB-O 3.42Å; P117-S130 WeakPolarHBondContact O-CB 3.48Å; P117-L133 HydrophobicContact CB-CB 4.22Å; P117-L133 HydrophobicContact CG-CB 3.97Å; P117-S134 WeakPolarHBondContact CG-OG 3.33Å; P117-L395 HydrophobicContact CG-CD2 3.85Å
118	Q	88.4	Confident	84.6	Confident	42 Å²	42	38.1 Å²	38.1	20%	0.196	21%	0.212	C	C	.	.	H	α-helix	trans	-60.9	-35.8	174.5	-78	166.6	9.6	0	0	112.7	V113 I114 T115 M116 K121 K122 D399	V113-Q118 HydrophobicContact CB-CB 4.28Å; V113-Q118 HydrophobicContact CG1-CB 4.19Å; I114-Q118 VanDerWaalsContact N-OE1 3.16Å; T115-Q118 WeakPolarHBondContact O-CB 3.49Å; T115-Q118 PolarHBondContact O-N 3.43Å; T115-Q118 WeakPolarHBondContact OG1-CB 3.47Å; T115-Q118 VanDerWaalsContact OG1-CD 3.26Å; T115-Q118 WeakPolarHBondContact OG1-CG 3.37Å; T115-Q118 PolarHBondContact OG1-N 3.09Å; M116-Q118 VanDerWaalsContact C-N 3.33Å; M116-Q118 PolarHBondContact O-N 3.41Å; Q118-K121 PolarHBondContact O-N 3.45Å; Q118-K122 WeakPolarHBondContact O-CB 3.25Å; Q118-K122 PolarHBondContact O-N 3.21Å; Q118-D399 WeakPolarHBondContact CG-OD1 2.91Å
119	Y	89.9	Confident	84.7	Confident	12 Å²	12	38.1 Å²	38.1	5%	0.047	21%	0.212	C	C	.	.	H	α-helix	trans	-58.6	-50.5	173.6	169.4	-107.8	0	0	0	111.7	V107 Y108 A111 T115 M116 P117 K121 K122 R123 F462 A465	V107-Y119 HydrophobicContact CG1-CE2 3.59Å; Y108-Y119 HydrophobicContact CD1-CD1 4.18Å; Y108-Y119 AromaticContact CD1-CD2 3.9Å; Y108-Y119 HydrophobicContact CD1-CD2 3.9Å; Y108-Y119 HydrophobicContact CD1-CE1 4.47Å; Y108-Y119 HydrophobicContact CD1-CE2 4.21Å; Y108-Y119 AromaticContact CD1-CG 3.89Å; Y108-Y119 HydrophobicContact CD1-CG 3.89Å; Y108-Y119 AromaticContact CE1-CD1 3.68Å; Y108-Y119 HydrophobicContact CE1-CD1 3.68Å; Y108-Y119 HydrophobicContact CE1-CD2 4.2Å; Y108-Y119 AromaticContact CE1-CE1 3.84Å; Y108-Y119 HydrophobicContact CE1-CE1 3.84Å; Y108-Y119 HydrophobicContact CE1-CE2 4.35Å; Y108-Y119 AromaticContact CE1-CG 3.87Å; Y108-Y119 HydrophobicContact CE1-CG 3.87Å; A111-Y119 HydrophobicContact CB-CD2 4.1Å; T115-Y119 PolarHBondContact O-N 3.23Å; M116-Y119 WeakPolarHBondContact O-CB 3.32Å; M116-Y119 PolarHBondContact O-N 3.42Å; P117-Y119 VanDerWaalsContact C-N 3.28Å; P117-Y119 PolarHBondContact O-N 3.49Å; Y119-K121 VanDerWaalsContact C-N 3.33Å; Y119-K121 PolarHBondContact O-N 3.01Å; Y119-K122 PolarHBondContact O-N 3.08Å; Y119-R123 VanDerWaalsContact O-CB 3.28Å; Y119-R123 WeakPolarHBondContact O-CB 3.28Å; Y119-R123 PolarHBondContact O-N 3.29Å; Y119-F462 HydrophobicContact CD1-CD1 4.16Å; Y119-F462 AromaticContact CD1-CE1 3.78Å; Y119-F462 HydrophobicContact CD1-CE1 3.78Å; Y119-F462 HydrophobicContact CE1-CD1 4.29Å; Y119-F462 HydrophobicContact CE1-CE1 4.37Å; Y119-A465 HydrophobicContact CE1-CB 4.27Å
120	L	89.8	Confident	85	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-65.8	-36.2	178	-66.4	-159.3	0	0	0	112.6	M116 P117 K122 R123 F124 I129 L133 V461 F462 A465	M116-L120 PolarHBondContact O-N 2.93Å; P117-L120 PolarHBondContact O-N 3.26Å; L120-K122 VanDerWaalsContact C-N 3.32Å; L120-K122 PolarHBondContact O-N 2.93Å; L120-R123 PolarHBondContact O-N 2.89Å; L120-F124 HydrophobicContact CB-CD2 4.19Å; L120-F124 HydrophobicContact CB-CE2 4.44Å; L120-F124 HydrophobicContact CD1-CE2 4.32Å; L120-F124 HydrophobicContact CD2-CD2 4.4Å; L120-F124 HydrophobicContact CD2-CE2 3.86Å; L120-F124 HydrophobicContact CG-CE2 4.45Å; L120-F124 WeakPolarHBondContact O-CB 3.43Å; L120-F124 PolarHBondContact O-N 3.26Å; L120-I129 HydrophobicContact CB-CG2 3.92Å; L120-I129 HydrophobicContact CD1-CG2 3.7Å; L120-L133 HydrophobicContact CB-CD1 4.48Å; L120-L133 HydrophobicContact CD1-CD1 3.32Å; L120-L133 HydrophobicContact CD1-CG 4.48Å; L120-L133 HydrophobicContact CG-CD1 4Å; L120-V461 HydrophobicContact CD1-CG1 3.64Å; L120-F462 HydrophobicContact CD1-CD2 4.29Å; L120-F462 HydrophobicContact CD1-CE2 3.86Å; L120-F462 HydrophobicContact CD1-CZ 4.19Å; L120-F462 HydrophobicContact CD2-CD1 4.43Å; L120-F462 HydrophobicContact CD2-CE1 4.27Å; L120-F462 HydrophobicContact CD2-CE2 4.47Å; L120-F462 HydrophobicContact CD2-CZ 4.27Å; L120-F462 HydrophobicContact CG-CE1 4.34Å; L120-F462 HydrophobicContact CG-CE2 4.07Å; L120-F462 HydrophobicContact CG-CZ 3.88Å; L120-A465 HydrophobicContact CD2-CB 3.91Å
121	K	88.4	Confident	85.7	Confident	92 Å²	92	35.5 Å²	35.5	40%	0.4	20%	0.196	S	C	.	.	H	α-helix	trans	-58.1	-44.9	172.3	-176.9	178.1	179.6	-176.3	0	111.4	P117 Q118 Y119 G125	P117-K121 PolarHBondContact O-N 3.34Å; Q118-K121 PolarHBondContact O-N 3.45Å; Y119-K121 VanDerWaalsContact C-N 3.33Å; Y119-K121 PolarHBondContact O-N 3.01Å; K121-G125 VanDerWaalsContact O-CA 3.23Å; K121-G125 WeakPolarHBondContact O-CA 3.22Å; K121-G125 PolarHBondContact O-N 3.47Å
122	K	85.4	Confident	86.2	Confident	123 Å²	123	36.2 Å²	36.2	54%	0.535	20%	0.195	S	C	.	.	H	α-helix	trans	-71	-35.1	179	-170.6	167	-179.3	170.8	0	112.3	A111 Q118 Y119 L120	A111-K122 PolarHBondContact O-NZ 2.84Å; Q118-K122 WeakPolarHBondContact O-CB 3.25Å; Q118-K122 PolarHBondContact O-N 3.21Å; Y119-K122 PolarHBondContact O-N 3.08Å; L120-K122 VanDerWaalsContact C-N 3.32Å; L120-K122 PolarHBondContact O-N 2.93Å
123	R	84.7	Confident	86.8	Confident	15 Å²	15	34 Å²	34	6%	0.057	17%	0.172	C	C	.	.	H	α-helix	trans	-74	-34.6	-179.4	174.5	60.2	-174.7	80.2	2.5	113.5	Y119 L120 A465 V468 K469	Y119-R123 VanDerWaalsContact O-CB 3.28Å; Y119-R123 WeakPolarHBondContact O-CB 3.28Å; Y119-R123 PolarHBondContact O-N 3.29Å; L120-R123 PolarHBondContact O-N 2.89Å; R123-A465 HydrophobicContact CG-CB 4.24Å; R123-A465 PolarHBondContact NE-O 3.32Å; R123-V468 PolarHBondContact NH2-O 2.83Å; R123-K469 PolarHBondContact NH2-O 3.17Å
124	F	86	Confident	87.2	Confident	9 Å²	9	33.7 Å²	33.7	4%	0.039	17%	0.17	C	C	.	.	H	α-helix	trans	-114.5	-10.3	-174.8	-59.7	-48.8	0	0	0	114.3	L120 G126 I129 V461 A465 V471 E473 A476 I542	L120-F124 HydrophobicContact CB-CD2 4.19Å; L120-F124 HydrophobicContact CB-CE2 4.44Å; L120-F124 HydrophobicContact CD1-CE2 4.32Å; L120-F124 HydrophobicContact CD2-CD2 4.4Å; L120-F124 HydrophobicContact CD2-CE2 3.86Å; L120-F124 HydrophobicContact CG-CE2 4.45Å; L120-F124 WeakPolarHBondContact O-CB 3.43Å; L120-F124 PolarHBondContact O-N 3.26Å; F124-G126 PolarHBondContact O-N 3.02Å; F124-I129 HydrophobicContact CB-CD1 4.26Å; F124-I129 HydrophobicContact CD2-CD1 3.77Å; F124-I129 HydrophobicContact CG-CD1 4.34Å; F124-V461 HydrophobicContact CE2-CG1 4.02Å; F124-A465 HydrophobicContact CE2-CB 4.22Å; F124-A465 HydrophobicContact CZ-CB 3.7Å; F124-V471 HydrophobicContact CE1-CB 4.38Å; F124-V471 HydrophobicContact CE1-CG1 3.86Å; F124-V471 VanDerWaalsContact CE1-O 3.25Å; F124-V471 WeakPolarHBondContact CE1-O 3.46Å; F124-V471 HydrophobicContact CZ-CG1 3.86Å; F124-E473 HydrophobicContact CB-CB 4.02Å; F124-E473 HydrophobicContact CB-CG 4.25Å; F124-A476 HydrophobicContact CD2-CB 4.14Å; F124-A476 HydrophobicContact CE2-CB 3.79Å; F124-A476 HydrophobicContact CZ-CB 4.18Å; F124-I542 HydrophobicContact CD1-CD1 4.21Å
125	G	76	Confident	87.7	Confident	38 Å²	38	35.2 Å²	35.2	39%	0.392	18%	0.18	S	C	.	.			trans	80.3	-17.1	178.5	0	0	0	0	0	115.2	K121	K121-G125 VanDerWaalsContact O-CA 3.23Å; K121-G125 WeakPolarHBondContact O-CA 3.22Å; K121-G125 PolarHBondContact O-N 3.47Å
126	G	76.7	Confident	87.7	Confident	14 Å²	14	36 Å²	36	14%	0.144	18%	0.184	C	C	.	.			trans	-84.4	138.8	-176.8	0	0	0	0	0	115.3	F124	F124-G126 PolarHBondContact O-N 3.02Å
127	A	81.2	Confident	87.7	Confident	48 Å²	48	36.8 Å²	36.8	40%	0.397	19%	0.19	S	C	.	.	H	α-helix	trans	-78.2	-23.1	172.2	0	0	0	0	0	113.1	L131 R403	A127-L131 PolarHBondContact O-N 3.14Å; A127-R403 VanDerWaalsContact O-CZ 3.31Å; A127-R403 PolarHBondContact O-NH1 3.34Å; A127-R403 PolarHBondContact O-NH2 3.1Å
128	R	89.2	Confident	87.7	Confident	171 Å²	171	37.1 Å²	37.1	65%	0.645	19%	0.192	S	C	*	.	H	α-helix	trans	-65.3	-50.2	-173.8	-62.2	176.8	-178	172.1	0.4	111.8	S130 L131 Y132 F477	R128-S130 VanDerWaalsContact C-N 3.33Å; R128-S130 PolarHBondContact O-N 3Å; R128-L131 PolarHBondContact O-N 3.39Å; R128-L131 VanDerWaalsContact O-N 3.16Å; R128-Y132 WeakPolarHBondContact O-CB 3.3Å; R128-Y132 PolarHBondContact O-N 2.74Å; R128-F477 HydrophobicContact CB-CD2 4.15Å; R128-F477 HydrophobicContact CB-CE2 4.17Å
129	I	88.3	Confident	87.8	Confident	1 Å²	1	38.8 Å²	38.8	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-57.6	-44.2	179.7	-63.1	174.3	0	0	0	112	L120 F124 L131 Y132 L133 E473 A476 F477 L480	L120-I129 HydrophobicContact CB-CG2 3.92Å; L120-I129 HydrophobicContact CD1-CG2 3.7Å; F124-I129 HydrophobicContact CB-CD1 4.26Å; F124-I129 HydrophobicContact CD2-CD1 3.77Å; F124-I129 HydrophobicContact CG-CD1 4.34Å; I129-L131 VanDerWaalsContact C-N 3.35Å; I129-L131 PolarHBondContact O-N 3.42Å; I129-Y132 PolarHBondContact O-N 2.94Å; I129-L133 HydrophobicContact CG2-CD1 4.31Å; I129-L133 HydrophobicContact CG2-CG 4.42Å; I129-L133 PolarHBondContact O-N 3.17Å; I129-E473 HydrophobicContact CD1-CB 4.36Å; I129-E473 HydrophobicContact CD1-CG 3.72Å; I129-E473 HydrophobicContact CG1-CG 4.32Å; I129-A476 HydrophobicContact CD1-CB 3.71Å; I129-F477 HydrophobicContact CG1-CB 4.08Å; I129-F477 HydrophobicContact CG1-CD2 4.44Å; I129-L480 HydrophobicContact CG2-CD1 4.18Å
130	S	88.9	Confident	87.7	Confident	1 Å²	1	38.3 Å²	38.3	1%	0.007	20%	0.2	C	C	.	.	H	α-helix	trans	-64.7	-38.8	180	154.8	0	0	0	0	112	P117 R128 S134 D399 R403	P117-S130 WeakPolarHBondContact CB-O 3.42Å; P117-S130 WeakPolarHBondContact O-CB 3.48Å; R128-S130 VanDerWaalsContact C-N 3.33Å; R128-S130 PolarHBondContact O-N 3Å; S130-S134 WeakPolarHBondContact O-CB 3.37Å; S130-S134 PolarHBondContact O-N 3.33Å; S130-S134 PolarHBondContact O-OG 2.97Å; S130-D399 PolarHBondContact OG-OD1 3.45Å; S130-R403 VanDerWaalsContact CB-NH2 3.26Å; S130-R403 PolarHBondContact OG-NH2 3.22Å
131	L	90.5	Very high	87.7	Confident	70 Å²	70	38.6 Å²	38.6	37%	0.366	20%	0.201	S	C	.	.	H	α-helix	trans	-66.1	-47	176.7	-176.2	61.4	0	0	0	110.8	A127 R128 I129 L133 S134 V135 I400 R403	A127-L131 PolarHBondContact O-N 3.14Å; R128-L131 PolarHBondContact O-N 3.39Å; R128-L131 VanDerWaalsContact O-N 3.16Å; I129-L131 VanDerWaalsContact C-N 3.35Å; I129-L131 PolarHBondContact O-N 3.42Å; L131-L133 PolarHBondContact O-N 3.42Å; L131-S134 PolarHBondContact O-N 3.38Å; L131-V135 HydrophobicContact CD1-CG2 4.26Å; L131-V135 HydrophobicContact CG-CG2 4.44Å; L131-V135 WeakPolarHBondContact O-CG2 3.5Å; L131-V135 PolarHBondContact O-N 3.12Å; L131-I400 HydrophobicContact CD1-CG1 4.14Å; L131-R403 VanDerWaalsContact N-NH2 3.13Å
132	Y	91.1	Very high	87.6	Confident	31 Å²	31	34.8 Å²	34.8	12%	0.122	19%	0.185	C	C	.	.	H	α-helix	trans	-54.5	-51.3	178.4	172.5	-89.6	0	0	0	111.4	R128 I129 S134 V135 I136 L480 I481 L484	R128-Y132 WeakPolarHBondContact O-CB 3.3Å; R128-Y132 PolarHBondContact O-N 2.74Å; I129-Y132 PolarHBondContact O-N 2.94Å; Y132-S134 PolarHBondContact O-N 3.01Å; Y132-V135 PolarHBondContact O-N 3.33Å; Y132-I136 HydrophobicContact CD1-CD1 4.27Å; Y132-I136 HydrophobicContact CD2-CD1 4.19Å; Y132-I136 HydrophobicContact CE1-CD1 3.51Å; Y132-I136 HydrophobicContact CE1-CG1 4.4Å; Y132-I136 HydrophobicContact CE2-CD1 3.45Å; Y132-I136 VanDerWaalsContact CE2-CD1 3.45Å; Y132-I136 HydrophobicContact CE2-CG1 4.31Å; Y132-I136 PolarHBondContact O-N 3.24Å; Y132-I136 WeakPolarHBondContact OH-CD1 3.44Å; Y132-L480 HydrophobicContact CD1-CB 4.19Å; Y132-L480 HydrophobicContact CD1-CD1 3.9Å; Y132-L480 HydrophobicContact CE1-CB 3.49Å; Y132-L480 VanDerWaalsContact CE1-CB 3.49Å; Y132-L480 HydrophobicContact CE1-CD1 3.85Å; Y132-L480 HydrophobicContact CE1-CD2 4.12Å; Y132-L480 HydrophobicContact CE1-CG 4Å; Y132-L480 PolarHBondContact OH-O 3.15Å; Y132-I481 HydrophobicContact CD2-CD1 3.85Å; Y132-I481 HydrophobicContact CE2-CD1 3.5Å; Y132-I481 VanDerWaalsContact CE2-CD1 3.5Å; Y132-I481 HydrophobicContact CE2-CG1 4.35Å; Y132-L484 HydrophobicContact CE2-CD2 4.23Å; Y132-L484 VanDerWaalsContact OH-CB 3.3Å; Y132-L484 WeakPolarHBondContact OH-CB 3.47Å
133	L	91.5	Very high	87.4	Confident	3 Å²	3	31.3 Å²	31.3	2%	0.016	17%	0.17	C	C	.	.	H	α-helix	trans	-65.1	-39.7	179.6	-76.8	-174.5	0	0	0	112.8	P117 L120 I129 L131 S137 I458 F462 L480	P117-L133 HydrophobicContact CB-CB 4.22Å; P117-L133 HydrophobicContact CG-CB 3.97Å; L120-L133 HydrophobicContact CB-CD1 4.48Å; L120-L133 HydrophobicContact CD1-CD1 3.32Å; L120-L133 HydrophobicContact CD1-CG 4.48Å; L120-L133 HydrophobicContact CG-CD1 4Å; I129-L133 HydrophobicContact CG2-CD1 4.31Å; I129-L133 HydrophobicContact CG2-CG 4.42Å; I129-L133 PolarHBondContact O-N 3.17Å; L131-L133 PolarHBondContact O-N 3.42Å; L133-S137 WeakPolarHBondContact O-CB 3.36Å; L133-S137 PolarHBondContact O-N 2.98Å; L133-S137 PolarHBondContact O-OG 3.21Å; L133-I458 HydrophobicContact CD2-CD1 4.26Å; L133-I458 HydrophobicContact CD2-CG1 3.97Å; L133-I458 HydrophobicContact CD2-CG2 4.08Å; L133-F462 HydrophobicContact CD1-CE2 3.71Å; L133-F462 HydrophobicContact CD1-CZ 4.15Å; L133-L480 HydrophobicContact CD2-CD1 4.23Å; L133-L480 HydrophobicContact CD2-CD2 4.46Å
134	S	91.5	Very high	87.4	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-62.1	-46.5	176.6	-62.9	0	0	0	0	111.1	P117 S130 L131 Y132 S137 L138 D399	P117-S134 WeakPolarHBondContact CG-OG 3.33Å; S130-S134 WeakPolarHBondContact O-CB 3.37Å; S130-S134 PolarHBondContact O-N 3.33Å; S130-S134 PolarHBondContact O-OG 2.97Å; L131-S134 PolarHBondContact O-N 3.38Å; Y132-S134 PolarHBondContact O-N 3.01Å; S134-S137 PolarHBondContact O-N 2.84Å; S134-L138 WeakPolarHBondContact O-CB 3.44Å; S134-L138 WeakPolarHBondContact O-CG 3.39Å; S134-L138 PolarHBondContact O-N 2.82Å; S134-D399 WeakPolarHBondContact OG-CB 3.47Å; S134-D399 PolarHBondContact OG-OD2 2.87Å
135	V	91.7	Very high	87.4	Confident	63 Å²	63	31.5 Å²	31.5	38%	0.382	17%	0.171	S	C	.	.	H	α-helix	trans	-63.2	-48.3	178.9	172.3	0	0	0	0	111.1	L131 Y132 S137 L138 L139 I400	L131-V135 HydrophobicContact CD1-CG2 4.26Å; L131-V135 HydrophobicContact CG-CG2 4.44Å; L131-V135 WeakPolarHBondContact O-CG2 3.5Å; L131-V135 PolarHBondContact O-N 3.12Å; Y132-V135 PolarHBondContact O-N 3.33Å; V135-S137 PolarHBondContact O-N 3.42Å; V135-L138 PolarHBondContact O-N 3.01Å; V135-L139 HydrophobicContact CG1-CD1 4.27Å; V135-L139 WeakPolarHBondContact O-CG 3.34Å; V135-L139 PolarHBondContact O-N 3.31Å; V135-I400 HydrophobicContact CG2-CD1 4.3Å
136	I	90.4	Very high	88	Confident	16 Å²	16	29.7 Å²	29.7	8%	0.082	15%	0.153	C	C	.	.	H	α-helix	trans	-65	-40.5	179	-71.4	-167.3	0	0	0	112.1	Y132 L138 L139 L140 I458 L484	Y132-I136 HydrophobicContact CD1-CD1 4.27Å; Y132-I136 HydrophobicContact CD2-CD1 4.19Å; Y132-I136 HydrophobicContact CE1-CD1 3.51Å; Y132-I136 HydrophobicContact CE1-CG1 4.4Å; Y132-I136 HydrophobicContact CE2-CD1 3.45Å; Y132-I136 VanDerWaalsContact CE2-CD1 3.45Å; Y132-I136 HydrophobicContact CE2-CG1 4.31Å; Y132-I136 PolarHBondContact O-N 3.24Å; Y132-I136 WeakPolarHBondContact OH-CD1 3.44Å; I136-L138 VanDerWaalsContact C-N 3.3Å; I136-L138 PolarHBondContact O-N 3.07Å; I136-L139 PolarHBondContact O-N 3.49Å; I136-L140 HydrophobicContact CG2-CD1 3.84Å; I136-L140 HydrophobicContact CG2-CG 4.17Å; I136-L140 WeakPolarHBondContact O-CB 3.25Å; I136-L140 VanDerWaalsContact O-CG 3.32Å; I136-L140 WeakPolarHBondContact O-CG 3.45Å; I136-L140 PolarHBondContact O-N 2.85Å; I136-I458 HydrophobicContact CG2-CD1 4.07Å; I136-L484 HydrophobicContact CD1-CD1 4.07Å; I136-L484 HydrophobicContact CD1-CD2 3.68Å; I136-L484 HydrophobicContact CD1-CG 4.35Å
137	S	91.3	Very high	88.4	Confident	21 Å²	21	29 Å²	29	15%	0.147	15%	0.146	C	C	.	.	H	α-helix	trans	-63.7	-38.5	178	-57.8	0	0	0	0	111.4	L133 S134 V135 L140 Y141	L133-S137 WeakPolarHBondContact O-CB 3.36Å; L133-S137 PolarHBondContact O-N 2.98Å; L133-S137 PolarHBondContact O-OG 3.21Å; S134-S137 PolarHBondContact O-N 2.84Å; V135-S137 PolarHBondContact O-N 3.42Å; S137-L140 PolarHBondContact O-N 2.9Å; S137-Y141 WeakPolarHBondContact O-CD1 3.44Å; S137-Y141 VanDerWaalsContact O-CG 3.29Å; S137-Y141 PolarHBondContact O-N 2.86Å
138	L	91.6	Very high	88.5	Confident	10 Å²	10	27 Å²	27	5%	0.052	13%	0.128	C	C	.	.	H	α-helix	trans	-64.7	-43.9	174.8	-70.8	171.3	0	0	0	111.8	S134 V135 I136 Y141 I142 L395 F396 I400 W420	S134-L138 WeakPolarHBondContact O-CB 3.44Å; S134-L138 WeakPolarHBondContact O-CG 3.39Å; S134-L138 PolarHBondContact O-N 2.82Å; V135-L138 PolarHBondContact O-N 3.01Å; I136-L138 VanDerWaalsContact C-N 3.3Å; I136-L138 PolarHBondContact O-N 3.07Å; L138-Y141 PolarHBondContact O-N 3.33Å; L138-I142 WeakPolarHBondContact O-CG1 3.5Å; L138-I142 PolarHBondContact O-N 2.71Å; L138-L395 HydrophobicContact CD2-CB 4.25Å; L138-F396 HydrophobicContact CD1-CB 4.38Å; L138-F396 HydrophobicContact CD1-CD2 4.35Å; L138-I400 HydrophobicContact CD1-CD1 3.72Å; L138-W420 HydrophobicContact CD1-CZ2 3.88Å; L138-W420 HydrophobicContact CD2-CZ2 4.05Å; L138-W420 HydrophobicContact CG-CZ2 4.43Å
139	L	88.7	Confident	88.4	Confident	77 Å²	77	19.7 Å²	19.7	40%	0.403	10%	0.102	S	C	.	.	H	α-helix	trans	-61.7	-44.5	174	-70.6	174.5	0	0	0	111.5	V135 I136 Y141 I142 F143	V135-L139 HydrophobicContact CG1-CD1 4.27Å; V135-L139 WeakPolarHBondContact O-CG 3.34Å; V135-L139 PolarHBondContact O-N 3.31Å; I136-L139 PolarHBondContact O-N 3.49Å; L139-Y141 VanDerWaalsContact C-N 3.31Å; L139-Y141 PolarHBondContact O-N 2.96Å; L139-I142 PolarHBondContact O-N 3.44Å; L139-F143 HydrophobicContact CB-CD2 4.27Å; L139-F143 HydrophobicContact CB-CE2 3.98Å; L139-F143 HydrophobicContact CD2-CE2 4.1Å; L139-F143 HydrophobicContact CD2-CZ 4.29Å; L139-F143 WeakPolarHBondContact O-CD2 3.41Å; L139-F143 WeakPolarHBondContact O-CG 3.22Å; L139-F143 PolarHBondContact O-N 3.38Å
140	L	88.2	Confident	88.3	Confident	2 Å²	2	19.8 Å²	19.8	1%	0.01	10%	0.103	C	C	.	.	H	α-helix	trans	-58.7	-42.1	175.9	-78.1	173.5	0	0	0	111.8	I136 S137 I142 F143 T144 W280 L454 I458	I136-L140 HydrophobicContact CG2-CD1 3.84Å; I136-L140 HydrophobicContact CG2-CG 4.17Å; I136-L140 WeakPolarHBondContact O-CB 3.25Å; I136-L140 VanDerWaalsContact O-CG 3.32Å; I136-L140 WeakPolarHBondContact O-CG 3.45Å; I136-L140 PolarHBondContact O-N 2.85Å; S137-L140 PolarHBondContact O-N 2.9Å; L140-I142 VanDerWaalsContact C-N 3.31Å; L140-I142 PolarHBondContact O-N 3.47Å; L140-F143 PolarHBondContact O-N 3.34Å; L140-T144 HydrophobicContact CD2-CG2 4.26Å; L140-T144 WeakPolarHBondContact O-CB 3.38Å; L140-T144 PolarHBondContact O-N 3.02Å; L140-T144 PolarHBondContact O-OG1 3Å; L140-W280 HydrophobicContact CD1-CZ2 3.95Å; L140-L454 HydrophobicContact CD2-CB 3.66Å; L140-L454 HydrophobicContact CD2-CD1 3.45Å; L140-L454 VanDerWaalsContact CD2-CD1 3.45Å; L140-L454 HydrophobicContact CD2-CG 4.21Å; L140-I458 HydrophobicContact CD1-CD1 4.1Å
141	Y	90.4	Very high	88.1	Confident	5 Å²	5	20.3 Å²	20.3	2%	0.02	11%	0.105	C	C	.	.	I	π-helix	trans	-61.8	-38.8	177.3	-71	-6.6	0	0	0	112.8	S137 L138 L139 K145 I146 D285 Q286 V287 I388 L395	S137-Y141 WeakPolarHBondContact O-CD1 3.44Å; S137-Y141 VanDerWaalsContact O-CG 3.29Å; S137-Y141 PolarHBondContact O-N 2.86Å; L138-Y141 PolarHBondContact O-N 3.33Å; L139-Y141 VanDerWaalsContact C-N 3.31Å; L139-Y141 PolarHBondContact O-N 2.96Å; Y141-K145 HydrophobicContact CD1-CD 4.08Å; Y141-K145 HydrophobicContact CD1-CG 4.48Å; Y141-K145 HydrophobicContact CE1-CD 4.27Å; Y141-K145 PolarHBondContact O-N 3.5Å; Y141-I146 VanDerWaalsContact O-CG1 3.31Å; Y141-I146 WeakPolarHBondContact O-CG1 3.29Å; Y141-I146 PolarHBondContact O-N 3.45Å; Y141-D285 PolarHBondContact OH-OD1 3.18Å; Y141-Q286 VanDerWaalsContact OH-CB 3.31Å; Y141-Q286 WeakPolarHBondContact OH-CB 3.38Å; Y141-Q286 PolarHBondContact OH-N 3.46Å; Y141-V287 HydrophobicContact CE1-CG2 4.36Å; Y141-V287 HydrophobicContact CE2-CG2 4.36Å; Y141-I388 HydrophobicContact CD2-CG2 4.01Å; Y141-I388 HydrophobicContact CG-CG2 3.99Å; Y141-L395 HydrophobicContact CE2-CD1 3.84Å
142	I	86.9	Confident	87.9	Confident	13 Å²	13	17 Å²	17	7%	0.067	9%	0.088	C	C	.	.	I	π-helix	trans	-66.1	-53.5	176.5	-63.6	165	0	0	0	109.9	L138 L139 L140 S147 I424 I427	L138-I142 WeakPolarHBondContact O-CG1 3.5Å; L138-I142 PolarHBondContact O-N 2.71Å; L139-I142 PolarHBondContact O-N 3.44Å; L140-I142 VanDerWaalsContact C-N 3.31Å; L140-I142 PolarHBondContact O-N 3.47Å; I142-S147 WeakPolarHBondContact O-CB 3.49Å; I142-S147 PolarHBondContact O-N 3.27Å; I142-S147 PolarHBondContact O-OG 3.37Å; I142-I424 HydrophobicContact CD1-CD1 4.42Å; I142-I424 HydrophobicContact CD1-CG1 4.1Å; I142-I424 HydrophobicContact CG1-CD1 3.93Å; I142-I424 HydrophobicContact CG1-CG1 3.74Å; I142-I427 HydrophobicContact CD1-CG2 4.09Å; I142-I427 HydrophobicContact CG2-CG2 4.12Å
143	F	81.4	Confident	87.8	Confident	50 Å²	50	15.5 Å²	15.5	22%	0.219	8%	0.082	C	C	.	.	I	π-helix	trans	-74.7	-32.6	-171.7	-60	-40.4	0	0	0	114.3	L139 L140 W431	L139-F143 HydrophobicContact CB-CD2 4.27Å; L139-F143 HydrophobicContact CB-CE2 3.98Å; L139-F143 HydrophobicContact CD2-CE2 4.1Å; L139-F143 HydrophobicContact CD2-CZ 4.29Å; L139-F143 WeakPolarHBondContact O-CD2 3.41Å; L139-F143 WeakPolarHBondContact O-CG 3.22Å; L139-F143 PolarHBondContact O-N 3.38Å; L140-F143 PolarHBondContact O-N 3.34Å; F143-W431 AromaticContact CD1-CD2 3.95Å; F143-W431 HydrophobicContact CD1-CD2 3.95Å; F143-W431 AromaticContact CD1-CE2 3.4Å; F143-W431 HydrophobicContact CD1-CE3 4.39Å; F143-W431 AromaticContact CD1-CH2 3.91Å; F143-W431 HydrophobicContact CD1-CH2 3.91Å; F143-W431 AromaticContact CD1-CZ2 3.39Å; F143-W431 HydrophobicContact CD1-CZ2 3.39Å; F143-W431 HydrophobicContact CD1-CZ3 4.38Å; F143-W431 AromaticContact CD1-NE1 3.73Å; F143-W431 AromaticContact CE1-CD2 3.88Å; F143-W431 HydrophobicContact CE1-CD2 3.88Å; F143-W431 AromaticContact CE1-CE2 3.63Å; F143-W431 AromaticContact CE1-CE3 3.84Å; F143-W431 HydrophobicContact CE1-CE3 3.84Å; F143-W431 AromaticContact CE1-CH2 3.37Å; F143-W431 HydrophobicContact CE1-CH2 3.37Å; F143-W431 AromaticContact CE1-CZ2 3.38Å; F143-W431 HydrophobicContact CE1-CZ2 3.38Å; F143-W431 AromaticContact CE1-CZ3 3.6Å; F143-W431 HydrophobicContact CE1-CZ3 3.6Å; F143-W431 HydrophobicContact CG-CZ2 4.44Å; F143-W431 HydrophobicContact CZ-CH2 4.15Å; F143-W431 HydrophobicContact CZ-CZ2 4.41Å; F143-W431 HydrophobicContact CZ-CZ3 4.43Å
144	T	83.3	Confident	87.5	Confident	2 Å²	2	15.4 Å²	15.4	1%	0.012	8%	0.081	C	C	.	.	I	π-helix	trans	-103.4	-67.7	-175.7	66.1	0	0	0	0	110.8	L140 V148 V450	L140-T144 HydrophobicContact CD2-CG2 4.26Å; L140-T144 WeakPolarHBondContact O-CB 3.38Å; L140-T144 PolarHBondContact O-N 3.02Å; L140-T144 PolarHBondContact O-OG1 3Å; T144-V148 WeakPolarHBondContact O-CB 3.39Å; T144-V148 WeakPolarHBondContact O-CG2 3.49Å; T144-V148 PolarHBondContact O-N 2.92Å; T144-V450 HydrophobicContact CG2-CB 4.15Å; T144-V450 HydrophobicContact CG2-CG1 3.58Å
145	K	87.1	Confident	87.1	Confident	25 Å²	25	15.8 Å²	15.8	11%	0.109	8%	0.083	C	C	.	.	I	π-helix	trans	-74.9	-53.7	-166.2	-61.7	-164.7	172.9	-171.8	0	114.4	Y141 S147 V148 D149 D285 I388	Y141-K145 HydrophobicContact CD1-CD 4.08Å; Y141-K145 HydrophobicContact CD1-CG 4.48Å; Y141-K145 HydrophobicContact CE1-CD 4.27Å; Y141-K145 PolarHBondContact O-N 3.5Å; K145-S147 PolarHBondContact O-N 2.93Å; K145-V148 PolarHBondContact O-N 3.32Å; K145-D149 PolarHBondContact O-N 3.31Å; K145-D285 WeakPolarHBondContact CE-OD2 3.43Å; K145-D285 VanDerWaalsContact NZ-CG 3.29Å; K145-D285 IonicContact NZ-OD1 2.84Å; K145-D285 PolarHBondContact NZ-OD1 3.41Å; K145-D285 IonicContact NZ-OD2 3.57Å; K145-D285 PolarHBondContact NZ-OD2 3.14Å; K145-I388 HydrophobicContact CB-CD1 3.54Å; K145-I388 HydrophobicContact CB-CG1 4.09Å; K145-I388 HydrophobicContact CD-CD1 4.28Å; K145-I388 HydrophobicContact CD-CG1 4.05Å
146	I	88.8	Confident	86.8	Confident	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.066	C	C	.	.	I	π-helix	trans	-65.2	-45.8	-174.2	-60.2	167.3	0	0	0	110.2	Y141 V148 D149 M150 L385 I388 F389 I424 S428	Y141-I146 VanDerWaalsContact O-CG1 3.31Å; Y141-I146 WeakPolarHBondContact O-CG1 3.29Å; Y141-I146 PolarHBondContact O-N 3.45Å; I146-V148 VanDerWaalsContact C-N 3.25Å; I146-V148 PolarHBondContact O-N 3.01Å; I146-D149 PolarHBondContact O-N 3.45Å; I146-M150 WeakPolarHBondContact O-CB 3.42Å; I146-M150 PolarHBondContact O-N 2.9Å; I146-L385 HydrophobicContact CG2-CD2 4.09Å; I146-I388 HydrophobicContact CD1-CG2 3.98Å; I146-I388 HydrophobicContact CG1-CB 4.44Å; I146-I388 HydrophobicContact CG1-CG2 3.59Å; I146-F389 HydrophobicContact CD1-CD1 4.36Å; I146-F389 HydrophobicContact CD1-CE1 3.97Å; I146-F389 HydrophobicContact CG1-CE1 4.2Å; I146-F389 HydrophobicContact CG2-CE1 4.33Å; I146-I424 HydrophobicContact CD1-CD1 3.64Å; I146-I424 HydrophobicContact CD1-CG1 3.83Å; I146-S428 VanDerWaalsContact CG2-OG 3.3Å; I146-S428 WeakPolarHBondContact CG2-OG 3.49Å
147	S	83.6	Confident	86.6	Confident	0 Å²	0	12.8 Å²	12.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-52.7	-43.9	178.1	-72.5	0	0	0	0	112.8	I142 K145 F151 W431	I142-S147 WeakPolarHBondContact O-CB 3.49Å; I142-S147 PolarHBondContact O-N 3.27Å; I142-S147 PolarHBondContact O-OG 3.37Å; K145-S147 PolarHBondContact O-N 2.93Å; S147-F151 VanDerWaalsContact O-CB 3.32Å; S147-F151 WeakPolarHBondContact O-CB 3.21Å; S147-F151 PolarHBondContact O-N 2.91Å; S147-W431 VanDerWaalsContact OG-CD1 3.26Å
148	V	83.1	Confident	86.3	Confident	5 Å²	5	14.1 Å²	14.1	3%	0.03	7%	0.069	C	C	.	.	H	α-helix	trans	-72.1	-52.4	-178.5	168.5	0	0	0	0	111.6	T144 K145 I146 M150 F151 S152 L443 I447	T144-V148 WeakPolarHBondContact O-CB 3.39Å; T144-V148 WeakPolarHBondContact O-CG2 3.49Å; T144-V148 PolarHBondContact O-N 2.92Å; K145-V148 PolarHBondContact O-N 3.32Å; I146-V148 VanDerWaalsContact C-N 3.25Å; I146-V148 PolarHBondContact O-N 3.01Å; V148-M150 PolarHBondContact O-N 3.22Å; V148-F151 PolarHBondContact O-N 3.49Å; V148-S152 VanDerWaalsContact O-CB 3.3Å; V148-S152 WeakPolarHBondContact O-CB 3.36Å; V148-S152 PolarHBondContact O-N 2.82Å; V148-S152 PolarHBondContact O-OG 3.43Å; V148-L443 HydrophobicContact CG1-CD2 3.87Å; V148-L443 HydrophobicContact CG1-CG 4.3Å; V148-L443 HydrophobicContact CG2-CD1 4.27Å; V148-I447 HydrophobicContact CB-CD1 3.8Å; V148-I447 HydrophobicContact CB-CG1 4.3Å; V148-I447 HydrophobicContact CG1-CD1 3.29Å; V148-I447 HydrophobicContact CG1-CG1 4.3Å; V148-I447 HydrophobicContact CG2-CB 4.45Å; V148-I447 HydrophobicContact CG2-CD1 3.17Å; V148-I447 HydrophobicContact CG2-CG1 3.16Å
149	D	87.8	Confident	85.9	Confident	18 Å²	18	15.2 Å²	15.2	10%	0.096	7%	0.074	C	C	.	.	H	α-helix	trans	-60.7	-39.6	-175.8	-78.5	-8.2	0	0	0	109.5	S69 K145 I146 S152 G153 L381 S384 L385 I388	S69-D149 PolarHBondContact OG-O 2.9Å; K145-D149 PolarHBondContact O-N 3.31Å; I146-D149 PolarHBondContact O-N 3.45Å; D149-S152 WeakPolarHBondContact CA-OG 3.42Å; D149-S152 PolarHBondContact O-OG 3.43Å; D149-G153 PolarHBondContact O-N 3.02Å; D149-L381 WeakPolarHBondContact O-CD2 3.22Å; D149-S384 VanDerWaalsContact OD2-CB 3.26Å; D149-S384 WeakPolarHBondContact OD2-CB 3.3Å; D149-L385 HydrophobicContact CB-CD2 3.6Å; D149-L385 HydrophobicContact CB-CG 3.87Å; D149-I388 WeakPolarHBondContact OD2-CD1 3.22Å
150	M	86.9	Confident	85.6	Confident	3 Å²	3	11.9 Å²	11.9	2%	0.015	6%	0.057	C	C	.	.	H	α-helix	trans	-63.4	-51.8	174.3	179.7	176.7	59	0	0	112.9	I146 V148 G153 A154 V169 L173 S428 I432	I146-M150 WeakPolarHBondContact O-CB 3.42Å; I146-M150 PolarHBondContact O-N 2.9Å; V148-M150 PolarHBondContact O-N 3.22Å; M150-G153 PolarHBondContact O-N 3.24Å; M150-A154 WeakPolarHBondContact O-CB 3.11Å; M150-A154 PolarHBondContact O-N 3.13Å; M150-V169 HydrophobicContact CG-CB 4.01Å; M150-V169 HydrophobicContact CG-CG1 3.36Å; M150-V169 HydrophobicContact CG-CG2 3.54Å; M150-V169 HydrophobicContact SD-CB 4.42Å; M150-V169 HydrophobicContact SD-CG1 3.25Å; M150-V169 WeakPolarHBondContact SD-CG1 3.35Å; M150-V169 HydrophobicContact SD-CG2 4.34Å; M150-L173 HydrophobicContact SD-CD1 3.67Å; M150-L173 HydrophobicContact SD-CD2 4.48Å; M150-L173 HydrophobicContact SD-CG 4.35Å; M150-S428 WeakPolarHBondContact CE-O 3.3Å; M150-I432 HydrophobicContact CE-CD1 4.2Å; M150-I432 HydrophobicContact CE-CG1 3.38Å; M150-I432 HydrophobicContact SD-CD1 3.96Å; M150-I432 HydrophobicContact SD-CG1 3.82Å
151	F	84.5	Confident	85.3	Confident	13 Å²	13	14.1 Å²	14.1	6%	0.057	7%	0.069	C	C	.	.	H	α-helix	trans	-64	-48.5	-179.6	176.9	-97.2	0	0	0	111.9	S147 V148 G153 A154 V155 I165 V435 Q436 L443	S147-F151 VanDerWaalsContact O-CB 3.32Å; S147-F151 WeakPolarHBondContact O-CB 3.21Å; S147-F151 PolarHBondContact O-N 2.91Å; V148-F151 PolarHBondContact O-N 3.49Å; F151-G153 VanDerWaalsContact C-N 3.29Å; F151-G153 PolarHBondContact O-N 3.16Å; F151-A154 PolarHBondContact O-N 3.04Å; F151-A154 VanDerWaalsContact O-N 3.12Å; F151-V155 HydrophobicContact CD1-CG2 4.14Å; F151-V155 HydrophobicContact CE1-CG2 3.58Å; F151-V155 HydrophobicContact CE2-CG2 4.11Å; F151-V155 HydrophobicContact CZ-CG2 3.55Å; F151-V155 WeakPolarHBondContact O-CG2 3.36Å; F151-V155 PolarHBondContact O-N 3.4Å; F151-I165 HydrophobicContact CD2-CD1 3.85Å; F151-I165 HydrophobicContact CE2-CD1 3.67Å; F151-V435 HydrophobicContact CB-CG1 4.5Å; F151-Q436 HydrophobicContact CE2-CG 4.45Å; F151-L443 HydrophobicContact CD1-CD1 3.87Å; F151-L443 HydrophobicContact CD1-CD2 3.78Å; F151-L443 HydrophobicContact CD1-CG 4.34Å; F151-L443 HydrophobicContact CE1-CD1 4.48Å; F151-L443 HydrophobicContact CE1-CD2 4.45Å
152	S	86.3	Confident	84.9	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-60.2	-38.8	176.3	54.9	0	0	0	0	112.2	S69 G70 V148 D149 A154 V155 F156	S69-S152 WeakPolarHBondContact CB-OG 3.42Å; S69-S152 PolarHBondContact OG-OG 3.27Å; G70-S152 PolarHBondContact N-OG 2.75Å; V148-S152 VanDerWaalsContact O-CB 3.3Å; V148-S152 WeakPolarHBondContact O-CB 3.36Å; V148-S152 PolarHBondContact O-N 2.82Å; V148-S152 PolarHBondContact O-OG 3.43Å; D149-S152 WeakPolarHBondContact CA-OG 3.42Å; D149-S152 PolarHBondContact O-OG 3.43Å; S152-A154 VanDerWaalsContact C-N 3.34Å; S152-V155 PolarHBondContact O-N 3.22Å; S152-F156 PolarHBondContact O-N 3.21Å
153	G	87.7	Confident	84.8	Confident	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-65	-38.6	173.9	0	0	0	0	0	113.4	D149 M150 F151 F156 I157	D149-G153 PolarHBondContact O-N 3.02Å; M150-G153 PolarHBondContact O-N 3.24Å; F151-G153 VanDerWaalsContact C-N 3.29Å; F151-G153 PolarHBondContact O-N 3.16Å; G153-F156 WeakPolarHBondContact O-CB 3.49Å; G153-F156 PolarHBondContact O-N 2.86Å; G153-I157 WeakPolarHBondContact O-CG1 3.48Å; G153-I157 PolarHBondContact O-N 2.92Å
154	A	86.2	Confident	85	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-69.7	-40.3	177.8	0	0	0	0	0	112.5	M150 F151 S152 F156 I157 Q158 I165 V169	M150-A154 WeakPolarHBondContact O-CB 3.11Å; M150-A154 PolarHBondContact O-N 3.13Å; F151-A154 PolarHBondContact O-N 3.04Å; F151-A154 VanDerWaalsContact O-N 3.12Å; S152-A154 VanDerWaalsContact C-N 3.34Å; A154-F156 VanDerWaalsContact C-N 3.25Å; A154-F156 PolarHBondContact O-N 3.36Å; A154-I157 PolarHBondContact O-N 3.31Å; A154-Q158 VanDerWaalsContact O-CB 3.25Å; A154-Q158 WeakPolarHBondContact O-CB 3.16Å; A154-Q158 PolarHBondContact O-N 3.02Å; A154-I165 HydrophobicContact CB-CD1 4.22Å; A154-I165 HydrophobicContact CB-CG1 3.39Å; A154-V169 HydrophobicContact CB-CG2 3.49Å; A154-V169 VanDerWaalsContact CB-CG2 3.49Å
155	V	84.1	Confident	84.9	Confident	8 Å²	8	23.7 Å²	23.7	5%	0.048	12%	0.123	C	C	.	.	H	α-helix	trans	-57	-44.1	170.7	170.3	0	0	0	0	110	V73 F151 S152 Q158 Q159 I355 P358	V73-V155 HydrophobicContact CG1-CG1 4.34Å; F151-V155 HydrophobicContact CD1-CG2 4.14Å; F151-V155 HydrophobicContact CE1-CG2 3.58Å; F151-V155 HydrophobicContact CE2-CG2 4.11Å; F151-V155 HydrophobicContact CZ-CG2 3.55Å; F151-V155 WeakPolarHBondContact O-CG2 3.36Å; F151-V155 PolarHBondContact O-N 3.4Å; S152-V155 PolarHBondContact O-N 3.22Å; V155-Q158 PolarHBondContact O-N 3.09Å; V155-Q159 HydrophobicContact CG1-CG 4.45Å; V155-Q159 VanDerWaalsContact O-CG 3.27Å; V155-Q159 WeakPolarHBondContact O-CG 3.38Å; V155-Q159 PolarHBondContact O-N 2.89Å; V155-I355 HydrophobicContact CG1-CG2 4.15Å; V155-P358 HydrophobicContact CG1-CG 4.49Å
156	F	84.4	Confident	84.8	Confident	3 Å²	3	27.3 Å²	27.3	1%	0.013	14%	0.137	C	C	.	.	H	α-helix	trans	-63.8	-48.1	179.6	-162.4	-95.6	0	0	0	112.7	S152 G153 A154 Q158 Q159 A160 P358 L374 M377 L378	S152-F156 PolarHBondContact O-N 3.21Å; G153-F156 WeakPolarHBondContact O-CB 3.49Å; G153-F156 PolarHBondContact O-N 2.86Å; A154-F156 VanDerWaalsContact C-N 3.25Å; A154-F156 PolarHBondContact O-N 3.36Å; F156-Q158 VanDerWaalsContact C-N 3.3Å; F156-Q158 PolarHBondContact O-N 3.5Å; F156-Q159 PolarHBondContact O-N 3.18Å; F156-A160 WeakPolarHBondContact O-CB 3.39Å; F156-A160 PolarHBondContact O-N 3.36Å; F156-P358 HydrophobicContact CD2-CB 3.69Å; F156-P358 HydrophobicContact CD2-CG 3.8Å; F156-P358 HydrophobicContact CE2-CB 3.94Å; F156-P358 HydrophobicContact CE2-CG 4.36Å; F156-L374 HydrophobicContact CD1-CD2 4.4Å; F156-L374 HydrophobicContact CE1-CB 4.35Å; F156-L374 HydrophobicContact CE1-CD2 3.35Å; F156-L374 HydrophobicContact CE1-CG 4.42Å; F156-L374 HydrophobicContact CE2-CD2 4.45Å; F156-L374 HydrophobicContact CZ-CD2 3.39Å; F156-M377 HydrophobicContact CD1-CB 4.43Å; F156-M377 HydrophobicContact CD2-CE 3.5Å; F156-M377 HydrophobicContact CD2-SD 4.27Å; F156-M377 HydrophobicContact CE1-CB 3.8Å; F156-M377 HydrophobicContact CE1-CE 4.49Å; F156-M377 HydrophobicContact CE1-SD 4.26Å; F156-M377 HydrophobicContact CE2-CB 4.33Å; F156-M377 HydrophobicContact CE2-CE 3.07Å; F156-M377 HydrophobicContact CE2-CG 4.45Å; F156-M377 HydrophobicContact CE2-SD 3.27Å; F156-M377 WeakPolarHBondContact CE2-SD 3.39Å; F156-M377 HydrophobicContact CG-CE 4.4Å; F156-M377 HydrophobicContact CZ-CB 3.73Å; F156-M377 HydrophobicContact CZ-CE 3.61Å; F156-M377 HydrophobicContact CZ-CG 4.03Å; F156-M377 HydrophobicContact CZ-SD 3.23Å; F156-M377 WeakPolarHBondContact CZ-SD 3.32Å; F156-L378 HydrophobicContact CD1-CD2 4.44Å
157	I	86.1	Confident	84.7	Confident	13 Å²	13	31.2 Å²	31.2	7%	0.067	16%	0.16	C	C	.	.	H	α-helix	trans	-62.7	-38.9	176.9	-67.1	166.8	0	0	0	111	G153 A154 A160 L161 W163 S168 L172 L378	G153-I157 WeakPolarHBondContact O-CG1 3.48Å; G153-I157 PolarHBondContact O-N 2.92Å; A154-I157 PolarHBondContact O-N 3.31Å; I157-A160 PolarHBondContact O-N 3.44Å; I157-L161 HydrophobicContact CG2-CB 4.41Å; I157-L161 HydrophobicContact CG2-CD1 4.11Å; I157-L161 HydrophobicContact CG2-CG 4.5Å; I157-L161 WeakPolarHBondContact O-CA 3.38Å; I157-L161 WeakPolarHBondContact O-CB 3.33Å; I157-L161 PolarHBondContact O-N 2.96Å; I157-W163 HydrophobicContact CG2-CB 4.09Å; I157-W163 HydrophobicContact CG2-CD2 4.21Å; I157-W163 HydrophobicContact CG2-CE3 3.98Å; I157-W163 HydrophobicContact CG2-CG 4.3Å; I157-S168 WeakPolarHBondContact CG2-OG 3.37Å; I157-L172 HydrophobicContact CD1-CB 4.48Å; I157-L172 HydrophobicContact CD1-CD1 4.03Å; I157-L378 HydrophobicContact CD1-CD2 4Å; I157-L378 HydrophobicContact CG1-CD2 3.6Å
158	Q	84.4	Confident	84.9	Confident	49 Å²	49	31.2 Å²	31.2	23%	0.229	16%	0.16	C	C	.	.	H	α-helix	trans	-62.3	-44.9	176.5	-179	-176.2	57.8	0	0	111.4	A154 V155 F156 A160 G162	A154-Q158 VanDerWaalsContact O-CB 3.25Å; A154-Q158 WeakPolarHBondContact O-CB 3.16Å; A154-Q158 PolarHBondContact O-N 3.02Å; V155-Q158 PolarHBondContact O-N 3.09Å; F156-Q158 VanDerWaalsContact C-N 3.3Å; F156-Q158 PolarHBondContact O-N 3.5Å; Q158-A160 VanDerWaalsContact C-N 3.33Å; Q158-A160 PolarHBondContact O-N 2.91Å; Q158-G162 WeakPolarHBondContact O-CA 3.41Å; Q158-G162 PolarHBondContact O-N 3.43Å
159	Q	83.7	Confident	85	Confident	34 Å²	34	31.1 Å²	31.1	16%	0.159	16%	0.159	C	C	.	.	H	α-helix	trans	-70.2	-29.5	178.9	-66.3	-61.7	-43.1	0	0	112.7	V155 F156 I355 P358	V155-Q159 HydrophobicContact CG1-CG 4.45Å; V155-Q159 VanDerWaalsContact O-CG 3.27Å; V155-Q159 WeakPolarHBondContact O-CG 3.38Å; V155-Q159 PolarHBondContact O-N 2.89Å; F156-Q159 PolarHBondContact O-N 3.18Å; Q159-I355 HydrophobicContact CG-CB 4.33Å; Q159-I355 HydrophobicContact CG-CG2 4.38Å; Q159-P358 HydrophobicContact CB-CB 3.83Å; Q159-P358 HydrophobicContact CG-CB 4.05Å
160	A	82.3	Confident	84.9	Confident	6 Å²	6	33.8 Å²	33.8	5%	0.05	17%	0.173	C	C	.	.	H	α-helix	trans	-89.6	-37.4	-178.2	0	0	0	0	0	114.6	V9 F156 I157 Q158 L374	V9-A160 VanDerWaalsContact O-O 3.08Å; F156-A160 WeakPolarHBondContact O-CB 3.39Å; F156-A160 PolarHBondContact O-N 3.36Å; I157-A160 PolarHBondContact O-N 3.44Å; Q158-A160 VanDerWaalsContact C-N 3.33Å; Q158-A160 PolarHBondContact O-N 2.91Å; A160-L374 HydrophobicContact CB-CD1 4.29Å; A160-L374 HydrophobicContact CB-CD2 3.71Å
161	L	82.6	Confident	84.8	Confident	50 Å²	50	35 Å²	35	26%	0.262	18%	0.184	S	C	.	.	H	α-helix	trans	-119.5	-8.1	-172.7	-59.4	-177	0	0	0	113.6	I11 I157 W163	I11-L161 HydrophobicContact CB-CD2 4.25Å; I11-L161 HydrophobicContact CD1-CD2 3.6Å; I11-L161 HydrophobicContact CG1-CD2 3.93Å; I157-L161 HydrophobicContact CG2-CB 4.41Å; I157-L161 HydrophobicContact CG2-CD1 4.11Å; I157-L161 HydrophobicContact CG2-CG 4.5Å; I157-L161 WeakPolarHBondContact O-CA 3.38Å; I157-L161 WeakPolarHBondContact O-CB 3.33Å; I157-L161 PolarHBondContact O-N 2.96Å; L161-W163 HydrophobicContact CB-CD2 4.39Å; L161-W163 HydrophobicContact CB-CG 4.01Å; L161-W163 HydrophobicContact CD1-CD2 4.21Å; L161-W163 HydrophobicContact CD1-CH2 4.49Å; L161-W163 HydrophobicContact CD1-CZ2 4.05Å; L161-W163 VanDerWaalsContact O-CD1 3.32Å; L161-W163 PolarHBondContact O-N 3.36Å
162	G	81.5	Confident	84.9	Confident	38 Å²	38	34.7 Å²	34.7	39%	0.392	18%	0.183	S	C	.	.			trans	69.2	14.3	-176.9	0	0	0	0	0	114.4	Q158	Q158-G162 WeakPolarHBondContact O-CA 3.41Å; Q158-G162 PolarHBondContact O-N 3.43Å
163	W	84.5	Confident	84.8	Confident	121 Å²	121	34.8 Å²	34.8	46%	0.458	18%	0.183	S	C	.	.			trans	-71.3	155.2	-177.9	-72.3	12.5	0	0	0	112.1	I157 L161 V167 S168 A171	I157-W163 HydrophobicContact CG2-CB 4.09Å; I157-W163 HydrophobicContact CG2-CD2 4.21Å; I157-W163 HydrophobicContact CG2-CE3 3.98Å; I157-W163 HydrophobicContact CG2-CG 4.3Å; L161-W163 HydrophobicContact CB-CD2 4.39Å; L161-W163 HydrophobicContact CB-CG 4.01Å; L161-W163 HydrophobicContact CD1-CD2 4.21Å; L161-W163 HydrophobicContact CD1-CH2 4.49Å; L161-W163 HydrophobicContact CD1-CZ2 4.05Å; L161-W163 VanDerWaalsContact O-CD1 3.32Å; L161-W163 PolarHBondContact O-N 3.36Å; W163-V167 HydrophobicContact CE3-CG1 4.14Å; W163-S168 WeakPolarHBondContact CB-OG 3.15Å; W163-A171 HydrophobicContact CZ3-CB 4.27Å
164	N	85.1	Confident	84.5	Confident	93 Å²	93	40.2 Å²	40.2	50%	0.497	21%	0.211	S	C	.	.			trans	-62.4	141.5	169.3	-176.5	-73.7	0	0	0	110.2	Y166 V167 S168	N164-Y166 VanDerWaalsContact C-N 3.29Å; N164-Y166 PolarHBondContact O-N 3.11Å; N164-Y166 WeakPolarHBondContact OD1-CB 3.4Å; N164-Y166 WeakPolarHBondContact OD1-CD2 3.41Å; N164-Y166 PolarHBondContact OD1-N 3.47Å; N164-V167 HydrophobicContact CB-CB 4.41Å; N164-V167 HydrophobicContact CB-CG2 4.1Å; N164-V167 PolarHBondContact O-N 3.23Å; N164-S168 WeakPolarHBondContact O-CB 3.23Å; N164-S168 PolarHBondContact O-N 3.37Å; N164-S168 PolarHBondContact O-OG 3.5Å
165	I	82.1	Confident	84.3	Confident	19 Å²	19	44.9 Å²	44.9	10%	0.097	24%	0.235	C	C	.	.	H	α-helix	trans	-56.7	-41.3	-177.9	-161	178.7	0	0	0	112.2	F151 A154 S168 V169	F151-I165 HydrophobicContact CD2-CD1 3.85Å; F151-I165 HydrophobicContact CE2-CD1 3.67Å; A154-I165 HydrophobicContact CB-CD1 4.22Å; A154-I165 HydrophobicContact CB-CG1 3.39Å; I165-S168 WeakPolarHBondContact O-CB 3.39Å; I165-S168 PolarHBondContact O-N 3.43Å; I165-V169 VanDerWaalsContact O-CG2 3.31Å; I165-V169 WeakPolarHBondContact O-CG2 3.33Å; I165-V169 PolarHBondContact O-N 3.29Å
166	Y	85.1	Confident	84.2	Confident	101 Å²	101	44.5 Å²	44.5	40%	0.396	23%	0.233	S	C	.	.	H	α-helix	trans	-68.2	-41.5	-179.3	-68.4	-81.9	0	0	0	112.2	N164 S168 V169 I170 I432 Q436	N164-Y166 VanDerWaalsContact C-N 3.29Å; N164-Y166 PolarHBondContact O-N 3.11Å; N164-Y166 WeakPolarHBondContact OD1-CB 3.4Å; N164-Y166 WeakPolarHBondContact OD1-CD2 3.41Å; N164-Y166 PolarHBondContact OD1-N 3.47Å; Y166-S168 VanDerWaalsContact C-N 3.33Å; Y166-V169 PolarHBondContact O-N 3.19Å; Y166-I170 VanDerWaalsContact O-CG1 3.29Å; Y166-I170 WeakPolarHBondContact O-CG1 3.29Å; Y166-I170 PolarHBondContact O-N 2.86Å; Y166-I432 HydrophobicContact CD1-CD1 4.39Å; Y166-I432 HydrophobicContact CE1-CB 4.48Å; Y166-I432 HydrophobicContact CE1-CG2 3.92Å; Y166-Q436 PolarHBondContact OH-OE1 2.85Å
167	V	87.1	Confident	84	Confident	82 Å²	82	44.8 Å²	44.8	50%	0.497	24%	0.236	S	C	.	.	H	α-helix	trans	-63.4	-43.9	176	177.9	0	0	0	0	110.1	W163 N164 V169 I170 A171	W163-V167 HydrophobicContact CE3-CG1 4.14Å; N164-V167 HydrophobicContact CB-CB 4.41Å; N164-V167 HydrophobicContact CB-CG2 4.1Å; N164-V167 PolarHBondContact O-N 3.23Å; V167-V169 PolarHBondContact O-N 3.2Å; V167-I170 PolarHBondContact O-N 3.42Å; V167-A171 WeakPolarHBondContact O-CB 3.32Å; V167-A171 PolarHBondContact O-N 2.68Å
168	S	87.2	Confident	83.6	Confident	0 Å²	0	50.1 Å²	50.1	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-59.3	-47.5	177.6	-55.5	0	0	0	0	111.6	I157 W163 N164 I165 Y166 L172	I157-S168 WeakPolarHBondContact CG2-OG 3.37Å; W163-S168 WeakPolarHBondContact CB-OG 3.15Å; N164-S168 WeakPolarHBondContact O-CB 3.23Å; N164-S168 PolarHBondContact O-N 3.37Å; N164-S168 PolarHBondContact O-OG 3.5Å; I165-S168 WeakPolarHBondContact O-CB 3.39Å; I165-S168 PolarHBondContact O-N 3.43Å; Y166-S168 VanDerWaalsContact C-N 3.33Å; S168-L172 WeakPolarHBondContact O-CB 3.39Å; S168-L172 PolarHBondContact O-N 3.2Å
169	V	85.8	Confident	83	Confident	2 Å²	2	49.7 Å²	49.7	1%	0.012	26%	0.26	C	S	.	.	H	α-helix	trans	-60.3	-50.4	176.5	164	0	0	0	0	112.1	M150 A154 I165 Y166 V167 A171 L172 L173 I432	M150-V169 HydrophobicContact CG-CB 4.01Å; M150-V169 HydrophobicContact CG-CG1 3.36Å; M150-V169 HydrophobicContact CG-CG2 3.54Å; M150-V169 HydrophobicContact SD-CB 4.42Å; M150-V169 HydrophobicContact SD-CG1 3.25Å; M150-V169 WeakPolarHBondContact SD-CG1 3.35Å; M150-V169 HydrophobicContact SD-CG2 4.34Å; A154-V169 HydrophobicContact CB-CG2 3.49Å; A154-V169 VanDerWaalsContact CB-CG2 3.49Å; I165-V169 VanDerWaalsContact O-CG2 3.31Å; I165-V169 WeakPolarHBondContact O-CG2 3.33Å; I165-V169 PolarHBondContact O-N 3.29Å; Y166-V169 PolarHBondContact O-N 3.19Å; V167-V169 PolarHBondContact O-N 3.2Å; V169-A171 VanDerWaalsContact C-N 3.33Å; V169-A171 PolarHBondContact O-N 3.24Å; V169-L172 WeakPolarHBondContact O-CB 3.44Å; V169-L172 PolarHBondContact O-N 3.49Å; V169-L173 HydrophobicContact CG1-CD1 3.71Å; V169-L173 HydrophobicContact CG1-CG 4.27Å; V169-L173 WeakPolarHBondContact O-CB 3.25Å; V169-L173 WeakPolarHBondContact O-CG 3.36Å; V169-L173 PolarHBondContact O-N 2.87Å; V169-I432 HydrophobicContact CB-CD1 4.26Å; V169-I432 HydrophobicContact CG1-CD1 3.58Å; V169-I432 HydrophobicContact CG2-CD1 4.34Å
170	I	85.8	Confident	82.6	Confident	75 Å²	75	48.2 Å²	48.2	39%	0.385	25%	0.253	S	S	.	.	H	α-helix	trans	-62.9	-44.3	-176.1	-69.6	166.8	0	0	0	110	Y166 V167 L172 L173 L174 I429	Y166-I170 VanDerWaalsContact O-CG1 3.29Å; Y166-I170 WeakPolarHBondContact O-CG1 3.29Å; Y166-I170 PolarHBondContact O-N 2.86Å; V167-I170 PolarHBondContact O-N 3.42Å; I170-L172 PolarHBondContact O-N 3.39Å; I170-L173 PolarHBondContact O-N 3.22Å; I170-L174 HydrophobicContact CG2-CD1 3.77Å; I170-L174 HydrophobicContact CG2-CG 4.33Å; I170-L174 WeakPolarHBondContact O-CB 3.49Å; I170-L174 VanDerWaalsContact O-CG 3.28Å; I170-L174 WeakPolarHBondContact O-CG 3.25Å; I170-L174 PolarHBondContact O-N 3.46Å; I170-I429 HydrophobicContact CG1-CD1 4.48Å
171	A	85	Confident	82.2	Confident	29 Å²	29	49.6 Å²	49.6	24%	0.24	26%	0.261	C	S	.	.	H	α-helix	trans	-59.9	-47.2	175.8	0	0	0	0	0	111.6	W163 V167 V169 L173 L174 I175	W163-A171 HydrophobicContact CZ3-CB 4.27Å; V167-A171 WeakPolarHBondContact O-CB 3.32Å; V167-A171 PolarHBondContact O-N 2.68Å; V169-A171 VanDerWaalsContact C-N 3.33Å; V169-A171 PolarHBondContact O-N 3.24Å; A171-L173 PolarHBondContact O-N 2.97Å; A171-L174 PolarHBondContact O-N 2.92Å; A171-I175 VanDerWaalsContact O-CG1 3.27Å; A171-I175 WeakPolarHBondContact O-CG1 3.5Å; A171-I175 PolarHBondContact O-N 3.21Å; A171-I175 VanDerWaalsContact O-N 3.08Å
172	L	85.2	Confident	81.5	Confident	6 Å²	6	50 Å²	50	3%	0.031	27%	0.266	C	S	.	.	H	α-helix	trans	-56.7	-50.1	177.9	-169.2	81.8	0	0	0	111.6	I157 S168 V169 I170 T176 L381 M382 L385	I157-L172 HydrophobicContact CD1-CB 4.48Å; I157-L172 HydrophobicContact CD1-CD1 4.03Å; S168-L172 WeakPolarHBondContact O-CB 3.39Å; S168-L172 PolarHBondContact O-N 3.2Å; V169-L172 WeakPolarHBondContact O-CB 3.44Å; V169-L172 PolarHBondContact O-N 3.49Å; I170-L172 PolarHBondContact O-N 3.39Å; L172-T176 WeakPolarHBondContact O-CB 3.24Å; L172-T176 PolarHBondContact O-N 3.21Å; L172-T176 PolarHBondContact O-OG1 3.01Å; L172-L381 HydrophobicContact CD1-CB 3.96Å; L172-L381 HydrophobicContact CD1-CD1 4.07Å; L172-L381 HydrophobicContact CD1-CG 4.46Å; L172-L381 HydrophobicContact CD2-CD2 4.23Å; L172-M382 HydrophobicContact CB-CE 4.22Å; L172-M382 HydrophobicContact CD1-CE 3.04Å; L172-M382 HydrophobicContact CD2-CE 4.49Å; L172-M382 HydrophobicContact CG-CE 3.32Å; L172-M382 WeakPolarHBondContact O-CE 3.25Å; L172-L385 HydrophobicContact CD2-CD1 3.96Å; L172-L385 HydrophobicContact CG-CD1 4.21Å
173	L	84.2	Confident	80.9	Confident	1 Å²	1	48.3 Å²	48.3	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-67.7	-40.6	-178.1	-70.8	174.5	0	0	0	112.6	M150 V169 I170 A171 T176 A177 L385 F389 V425 I429	M150-L173 HydrophobicContact SD-CD1 3.67Å; M150-L173 HydrophobicContact SD-CD2 4.48Å; M150-L173 HydrophobicContact SD-CG 4.35Å; V169-L173 HydrophobicContact CG1-CD1 3.71Å; V169-L173 HydrophobicContact CG1-CG 4.27Å; V169-L173 WeakPolarHBondContact O-CB 3.25Å; V169-L173 WeakPolarHBondContact O-CG 3.36Å; V169-L173 PolarHBondContact O-N 2.87Å; I170-L173 PolarHBondContact O-N 3.22Å; A171-L173 PolarHBondContact O-N 2.97Å; L173-T176 PolarHBondContact O-N 3.23Å; L173-A177 VanDerWaalsContact O-CB 3.25Å; L173-A177 WeakPolarHBondContact O-CB 3.46Å; L173-A177 PolarHBondContact O-N 3.49Å; L173-L385 HydrophobicContact CD2-CD1 4.3Å; L173-F389 HydrophobicContact CD2-CZ 3.97Å; L173-V425 HydrophobicContact CB-CG1 4.08Å; L173-V425 HydrophobicContact CD1-CG1 4.21Å; L173-I429 HydrophobicContact CD1-CD1 3.85Å; L173-I429 HydrophobicContact CD1-CG1 3.4Å; L173-I429 VanDerWaalsContact CD1-CG1 3.4Å
174	L	81.4	Confident	80.5	Confident	114 Å²	114	42.7 Å²	42.7	60%	0.597	23%	0.228	S	C	*	.	H	α-helix	trans	-63.6	-46.9	178.5	-76.2	172.8	0	0	0	111.7	I170 A171 T176 A177 L178	I170-L174 HydrophobicContact CG2-CD1 3.77Å; I170-L174 HydrophobicContact CG2-CG 4.33Å; I170-L174 WeakPolarHBondContact O-CB 3.49Å; I170-L174 VanDerWaalsContact O-CG 3.28Å; I170-L174 WeakPolarHBondContact O-CG 3.25Å; I170-L174 PolarHBondContact O-N 3.46Å; A171-L174 PolarHBondContact O-N 2.92Å; L174-T176 VanDerWaalsContact C-N 3.35Å; L174-A177 PolarHBondContact O-N 3.29Å; L174-L178 PolarHBondContact O-N 2.83Å
175	I	82.3	Confident	80.3	Confident	99 Å²	99	38.2 Å²	38.2	51%	0.508	20%	0.204	S	C	.	.	H	α-helix	trans	-63	-44.9	178.1	-64.9	168.1	0	0	0	110	A171 A177 L178 Y179 M382	A171-I175 VanDerWaalsContact O-CG1 3.27Å; A171-I175 WeakPolarHBondContact O-CG1 3.5Å; A171-I175 PolarHBondContact O-N 3.21Å; A171-I175 VanDerWaalsContact O-N 3.08Å; I175-A177 PolarHBondContact O-N 3.5Å; I175-L178 PolarHBondContact O-N 3.12Å; I175-Y179 WeakPolarHBondContact O-CB 3.34Å; I175-Y179 PolarHBondContact O-N 3.38Å; I175-Y179 VanDerWaalsContact O-N 3.09Å; I175-M382 HydrophobicContact CB-SD 3.94Å; I175-M382 HydrophobicContact CG2-SD 3.67Å
176	T	83.3	Confident	80.2	Confident	0 Å²	0	37.6 Å²	37.6	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-59.7	-47.5	177	-54.7	0	0	0	0	111.6	L172 L173 L174 L178 Y179 T180 M382 L385 A386 F389	L172-T176 WeakPolarHBondContact O-CB 3.24Å; L172-T176 PolarHBondContact O-N 3.21Å; L172-T176 PolarHBondContact O-OG1 3.01Å; L173-T176 PolarHBondContact O-N 3.23Å; L174-T176 VanDerWaalsContact C-N 3.35Å; T176-L178 VanDerWaalsContact C-N 3.35Å; T176-L178 PolarHBondContact O-N 3.5Å; T176-Y179 PolarHBondContact O-N 3.32Å; T176-T180 WeakPolarHBondContact O-CB 3.43Å; T176-T180 PolarHBondContact O-N 3.45Å; T176-T180 PolarHBondContact O-OG1 3.43Å; T176-M382 WeakPolarHBondContact OG1-CE 3.23Å; T176-M382 PolarHBondContact OG1-SD 3.34Å; T176-L385 HydrophobicContact CG2-CB 3.49Å; T176-L385 VanDerWaalsContact CG2-CB 3.49Å; T176-A386 HydrophobicContact CG2-CB 4.12Å; T176-F389 HydrophobicContact CG2-CD2 3.89Å; T176-F389 HydrophobicContact CG2-CE2 3.65Å
177	A	80	Confident	80	Confident	8 Å²	8	32.8 Å²	32.8	7%	0.066	18%	0.183	C	C	.	.	H	α-helix	trans	-61.9	-44.4	-177.1	0	0	0	0	0	111	L173 L174 I175 Y179 T180 V181	L173-A177 VanDerWaalsContact O-CB 3.25Å; L173-A177 WeakPolarHBondContact O-CB 3.46Å; L173-A177 PolarHBondContact O-N 3.49Å; L174-A177 PolarHBondContact O-N 3.29Å; I175-A177 PolarHBondContact O-N 3.5Å; A177-Y179 VanDerWaalsContact C-N 3.34Å; A177-Y179 PolarHBondContact O-N 3.25Å; A177-T180 PolarHBondContact O-N 2.97Å; A177-V181 WeakPolarHBondContact O-CB 3.42Å; A177-V181 VanDerWaalsContact O-CG2 3.23Å; A177-V181 WeakPolarHBondContact O-CG2 3.48Å; A177-V181 PolarHBondContact O-N 2.88Å
178	L	76.8	Confident	79.8	Confident	126 Å²	126	28.9 Å²	28.9	66%	0.66	16%	0.159	S	C	*	.	H	α-helix	trans	-58.9	-46.3	176.5	-177.3	65.7	0	0	0	111.7	L174 I175 T176 T182	L174-L178 PolarHBondContact O-N 2.83Å; I175-L178 PolarHBondContact O-N 3.12Å; T176-L178 VanDerWaalsContact C-N 3.35Å; T176-L178 PolarHBondContact O-N 3.5Å; L178-T182 WeakPolarHBondContact O-CG2 3.35Å; L178-T182 PolarHBondContact O-N 3.14Å; L178-T182 PolarHBondContact O-OG1 3.37Å
179	Y	72.5	Confident	79.9	Confident	40 Å²	40	28.9 Å²	28.9	16%	0.157	16%	0.159	C	C	.	.	H	α-helix	trans	-65.1	-40.6	178.4	176.9	-106.5	0	0	0	112.4	I175 T176 A177 T182 G183 L188 T191 A386	I175-Y179 WeakPolarHBondContact O-CB 3.34Å; I175-Y179 PolarHBondContact O-N 3.38Å; I175-Y179 VanDerWaalsContact O-N 3.09Å; T176-Y179 PolarHBondContact O-N 3.32Å; A177-Y179 VanDerWaalsContact C-N 3.34Å; A177-Y179 PolarHBondContact O-N 3.25Å; Y179-T182 PolarHBondContact O-N 2.89Å; Y179-T182 PolarHBondContact O-OG1 3.36Å; Y179-T182 VanDerWaalsContact O-OG1 3.1Å; Y179-G183 PolarHBondContact O-N 2.9Å; Y179-L188 HydrophobicContact CD1-CD2 4.12Å; Y179-L188 HydrophobicContact CE1-CD2 3.34Å; Y179-T191 VanDerWaalsContact OH-CG2 3.24Å; Y179-T191 WeakPolarHBondContact OH-CG2 3.17Å; Y179-T191 PolarHBondContact OH-OG1 3.48Å; Y179-A386 HydrophobicContact CD1-CB 4.23Å; Y179-A386 HydrophobicContact CE1-CB 4.46Å
180	T	75.8	Confident	79.9	Confident	2 Å²	2	32 Å²	32	1%	0.012	17%	0.171	C	C	.	.	H	α-helix	trans	-69.2	-45.1	-178.7	-52.8	0	0	0	0	112.2	Y46 T176 A177 T182 G183 A386 F389	Y46-T180 PolarHBondContact OH-O 3.26Å; T176-T180 WeakPolarHBondContact O-CB 3.43Å; T176-T180 PolarHBondContact O-N 3.45Å; T176-T180 PolarHBondContact O-OG1 3.43Å; A177-T180 PolarHBondContact O-N 2.97Å; T180-T182 PolarHBondContact O-N 3.02Å; T180-G183 PolarHBondContact O-N 2.92Å; T180-A386 HydrophobicContact CG2-CB 4.36Å; T180-A386 VanDerWaalsContact OG1-CA 3.27Å; T180-A386 WeakPolarHBondContact OG1-CA 3.23Å; T180-A386 WeakPolarHBondContact OG1-CB 3.4Å; T180-F389 HydrophobicContact CG2-CB 3.86Å
181	V	72.3	Confident	79.9	Confident	35 Å²	35	28.6 Å²	28.6	21%	0.212	15%	0.154	C	C	.	.	H	α-helix	trans	-60.3	-32.1	-179.2	166.7	0	0	0	0	111.2	A177 R418	A177-V181 WeakPolarHBondContact O-CB 3.42Å; A177-V181 VanDerWaalsContact O-CG2 3.23Å; A177-V181 WeakPolarHBondContact O-CG2 3.48Å; A177-V181 PolarHBondContact O-N 2.88Å; V181-R418 HydrophobicContact CG1-CB 4.37Å; V181-R418 HydrophobicContact CG1-CG 3.94Å; V181-R418 HydrophobicContact CG2-CB 4.36Å; V181-R418 HydrophobicContact CG2-CG 4.36Å; V181-R418 PolarHBondContact O-NE 3.16Å; V181-R418 PolarHBondContact O-NH2 2.82Å; V181-R418 VanDerWaalsContact O-NH2 3.17Å
182	T	68.6	Low	80.1	Confident	59 Å²	59	27.2 Å²	27.2	36%	0.362	14%	0.143	S	C	.	.	H	α-helix	trans	-92.9	-30.2	-176.5	55.9	0	0	0	0	114.3	R40 L178 Y179 T180	R40-T182 VanDerWaalsContact CZ-O 3.29Å; R40-T182 PolarHBondContact NH1-O 2.84Å; R40-T182 VanDerWaalsContact NH1-O 3.08Å; R40-T182 PolarHBondContact NH2-O 3.24Å; R40-T182 VanDerWaalsContact NH2-O 3.14Å; L178-T182 WeakPolarHBondContact O-CG2 3.35Å; L178-T182 PolarHBondContact O-N 3.14Å; L178-T182 PolarHBondContact O-OG1 3.37Å; Y179-T182 PolarHBondContact O-N 2.89Å; Y179-T182 PolarHBondContact O-OG1 3.36Å; Y179-T182 VanDerWaalsContact O-OG1 3.1Å; T180-T182 PolarHBondContact O-N 3.02Å
183	G	69.7	Low	80.3	Confident	2 Å²	2	27.1 Å²	27.1	2%	0.021	14%	0.142	C	C	.	.	H	α-helix	trans	-86.4	-41	-167.9	0	0	0	0	0	118.2	R40 Y179 T180 A187	R40-G183 VanDerWaalsContact NH2-C 3.27Å; R40-G183 PolarHBondContact NH2-O 2.79Å; Y179-G183 PolarHBondContact O-N 2.9Å; T180-G183 PolarHBondContact O-N 2.92Å; G183-A187 VanDerWaalsContact O-CB 3.23Å; G183-A187 WeakPolarHBondContact O-CB 3.33Å
184	G	76	Confident	80.5	Confident	3 Å²	3	30 Å²	30	3%	0.031	16%	0.155	C	C	.	.	H	α-helix	trans	61.3	172.6	-170.8	0	0	0	0	0	114.2	Y46 A186 A187 L188	Y46-G184 VanDerWaalsContact CE2-CA 3.44Å; G184-A186 VanDerWaalsContact C-N 3.33Å; G184-A186 PolarHBondContact O-N 2.97Å; G184-A187 PolarHBondContact O-N 3.37Å; G184-L188 WeakPolarHBondContact O-CG 3.43Å; G184-L188 PolarHBondContact O-N 2.82Å
185	L	79.4	Confident	80.8	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-62	-34.9	-168.9	-174.7	65.9	0	0	0	113.9	Y46 F47 L188 M189 Q290 A294	Y46-L185 WeakPolarHBondContact O-CB 3.39Å; Y46-L185 PolarHBondContact O-N 2.9Å; F47-L185 WeakPolarHBondContact O-CD2 3.45Å; L185-L188 WeakPolarHBondContact O-CB 3.48Å; L185-L188 PolarHBondContact O-N 3.38Å; L185-M189 HydrophobicContact CD1-CG 4.28Å; L185-M189 HydrophobicContact CD2-SD 4.42Å; L185-M189 HydrophobicContact CG-CG 4.3Å; L185-M189 HydrophobicContact CG-SD 4.17Å; L185-M189 WeakPolarHBondContact O-CG 3.46Å; L185-M189 PolarHBondContact O-N 3.33Å; L185-Q290 HydrophobicContact CD2-CG 3.98Å; L185-A294 HydrophobicContact CD2-CB 4.24Å
186	A	80.5	Confident	81.2	Confident	5 Å²	5	20.2 Å²	20.2	4%	0.041	10%	0.104	C	C	.	.	H	α-helix	trans	-64.8	-47	-177.7	0	0	0	0	0	112.7	T38 A49 M53 G184 L188 M189 Y190	T38-A186 HydrophobicContact CG2-CB 3.79Å; A49-A186 HydrophobicContact CB-CB 3.65Å; M53-A186 HydrophobicContact CE-CB 3.83Å; G184-A186 VanDerWaalsContact C-N 3.33Å; G184-A186 PolarHBondContact O-N 2.97Å; A186-L188 VanDerWaalsContact C-N 3.28Å; A186-L188 PolarHBondContact O-N 3.11Å; A186-M189 PolarHBondContact O-N 2.93Å; A186-Y190 WeakPolarHBondContact O-CD2 3.43Å; A186-Y190 PolarHBondContact O-N 3.48Å
187	A	81.4	Confident	81.6	Confident	1 Å²	1	26.6 Å²	26.6	1%	0.008	13%	0.132	C	C	.	.	H	α-helix	trans	-62.9	-41.1	178.6	0	0	0	0	0	110.6	S34 G183 G184 M189 Y190 T191	S34-A187 WeakPolarHBondContact OG-CA 3.5Å; G183-A187 VanDerWaalsContact O-CB 3.23Å; G183-A187 WeakPolarHBondContact O-CB 3.33Å; G184-A187 PolarHBondContact O-N 3.37Å; A187-M189 PolarHBondContact O-N 3.35Å; A187-Y190 PolarHBondContact O-N 3.43Å; A187-T191 PolarHBondContact O-N 2.9Å; A187-T191 PolarHBondContact O-OG1 3.21Å; A187-T191 VanDerWaalsContact O-OG1 3.07Å
188	L	83.3	Confident	82.1	Confident	0 Å²	0	27.4 Å²	27.4	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-56.7	-50.1	175.2	-66	174.6	0	0	0	111.6	Y179 G184 L185 A186 Y190 T191 D192 A386 N390	Y179-L188 HydrophobicContact CD1-CD2 4.12Å; Y179-L188 HydrophobicContact CE1-CD2 3.34Å; G184-L188 WeakPolarHBondContact O-CG 3.43Å; G184-L188 PolarHBondContact O-N 2.82Å; L185-L188 WeakPolarHBondContact O-CB 3.48Å; L185-L188 PolarHBondContact O-N 3.38Å; A186-L188 VanDerWaalsContact C-N 3.28Å; A186-L188 PolarHBondContact O-N 3.11Å; L188-Y190 VanDerWaalsContact C-N 3.33Å; L188-Y190 PolarHBondContact O-N 3.49Å; L188-T191 PolarHBondContact O-N 3.31Å; L188-T191 PolarHBondContact O-OG1 2.88Å; L188-D192 WeakPolarHBondContact O-CB 3.1Å; L188-D192 PolarHBondContact O-N 3.38Å; L188-A386 HydrophobicContact CD1-CB 4.4Å; L188-A386 HydrophobicContact CD2-CB 3.56Å; L188-N390 HydrophobicContact CD1-CB 4.12Å
189	M	87.9	Confident	82.8	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-64.2	-35.1	-177.9	-69.9	-174.7	67.6	0	0	113.4	M53 V58 L185 A186 A187 T193 R291 A294	M53-M189 HydrophobicContact CB-CE 3.95Å; M53-M189 HydrophobicContact CE-CB 4Å; M53-M189 HydrophobicContact CE-SD 4.24Å; M53-M189 HydrophobicContact CG-CE 3.7Å; M53-M189 HydrophobicContact CG-SD 3.78Å; M53-M189 HydrophobicContact SD-CB 4.32Å; M53-M189 HydrophobicContact SD-CE 4.33Å; M53-M189 HydrophobicContact SD-SD 4.38Å; V58-M189 HydrophobicContact CG2-CE 4.14Å; L185-M189 HydrophobicContact CD1-CG 4.28Å; L185-M189 HydrophobicContact CD2-SD 4.42Å; L185-M189 HydrophobicContact CG-CG 4.3Å; L185-M189 HydrophobicContact CG-SD 4.17Å; L185-M189 WeakPolarHBondContact O-CG 3.46Å; L185-M189 PolarHBondContact O-N 3.33Å; A186-M189 PolarHBondContact O-N 2.93Å; A187-M189 PolarHBondContact O-N 3.35Å; M189-T193 PolarHBondContact O-N 2.89Å; M189-T193 VanDerWaalsContact O-N 3.08Å; M189-T193 PolarHBondContact O-OG1 2.99Å; M189-R291 HydrophobicContact CE-CB 4.46Å; M189-A294 HydrophobicContact CE-CB 4.46Å; M189-A294 HydrophobicContact SD-CB 3.85Å
190	Y	86.4	Confident	83.7	Confident	67 Å²	67	20.8 Å²	20.8	26%	0.263	10%	0.104	S	C	.	.	H	α-helix	trans	-70.5	-43.5	176.2	-78	-65.9	0	0	0	112.3	S34 M53 W56 A186 A187 L188 D192 T193 F194	S34-Y190 WeakPolarHBondContact OG-CD2 3.19Å; M53-Y190 HydrophobicContact CE-CD2 4.17Å; M53-Y190 HydrophobicContact CE-CE2 3.75Å; M53-Y190 HydrophobicContact SD-CE2 4.18Å; W56-Y190 HydrophobicContact CH2-CE1 4.22Å; A186-Y190 WeakPolarHBondContact O-CD2 3.43Å; A186-Y190 PolarHBondContact O-N 3.48Å; A187-Y190 PolarHBondContact O-N 3.43Å; L188-Y190 VanDerWaalsContact C-N 3.33Å; L188-Y190 PolarHBondContact O-N 3.49Å; Y190-D192 VanDerWaalsContact C-N 3.35Å; Y190-T193 PolarHBondContact O-N 2.97Å; Y190-F194 PolarHBondContact O-N 2.97Å; Y190-F194 VanDerWaalsContact O-N 3.17Å
191	T	85.9	Confident	84.6	Confident	4 Å²	4	23.2 Å²	23.2	3%	0.025	12%	0.124	C	C	.	.	H	α-helix	trans	-65.4	-39.5	175.1	51.2	0	0	0	0	111.7	V27 V30 Y179 A187 L188 T193 F194 Q195	V27-T191 HydrophobicContact CG1-CG2 4.07Å; V30-T191 HydrophobicContact CB-CG2 4.41Å; V30-T191 HydrophobicContact CG1-CG2 4.1Å; Y179-T191 VanDerWaalsContact OH-CG2 3.24Å; Y179-T191 WeakPolarHBondContact OH-CG2 3.17Å; Y179-T191 PolarHBondContact OH-OG1 3.48Å; A187-T191 PolarHBondContact O-N 2.9Å; A187-T191 PolarHBondContact O-OG1 3.21Å; A187-T191 VanDerWaalsContact O-OG1 3.07Å; L188-T191 PolarHBondContact O-N 3.31Å; L188-T191 PolarHBondContact O-OG1 2.88Å; T191-T193 PolarHBondContact O-N 2.92Å; T191-F194 PolarHBondContact O-N 2.91Å; T191-Q195 VanDerWaalsContact O-CB 3.23Å; T191-Q195 WeakPolarHBondContact O-CB 3.11Å; T191-Q195 PolarHBondContact O-N 3.1Å
192	D	88.9	Confident	85.5	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58	-41	175	-69.4	-3.4	0	0	0	111	S61 A64 L188 Y190 Q195 T196 R291 S383	S61-D192 PolarHBondContact OG-OD2 3.42Å; A64-D192 HydrophobicContact CB-CB 4Å; L188-D192 WeakPolarHBondContact O-CB 3.1Å; L188-D192 PolarHBondContact O-N 3.38Å; Y190-D192 VanDerWaalsContact C-N 3.35Å; D192-Q195 PolarHBondContact O-N 3.27Å; D192-T196 WeakPolarHBondContact O-CB 3.15Å; D192-T196 PolarHBondContact O-N 2.6Å; D192-T196 PolarHBondContact O-OG1 2.92Å; D192-R291 IonicContact OD2-CZ 3.8Å; D192-R291 IonicContact OD2-NE 3.69Å; D192-R291 IonicContact OD2-NH2 3.75Å; D192-R291 PolarHBondContact OD2-NH2 3.04Å; D192-S383 WeakPolarHBondContact OD1-CB 3.42Å; D192-S383 PolarHBondContact OD1-OG 3.14Å
193	T	89.5	Confident	86.7	Confident	4 Å²	4	19.5 Å²	19.5	3%	0.025	10%	0.104	C	C	.	.	H	α-helix	trans	-65.2	-49.5	-179.2	-51.4	0	0	0	0	110.8	W56 S57 A60 M189 Y190 T191 Q195 T196 F197	W56-T193 HydrophobicContact CE3-CG2 3.47Å; W56-T193 VanDerWaalsContact CE3-CG2 3.47Å; W56-T193 HydrophobicContact CZ3-CG2 3.43Å; W56-T193 VanDerWaalsContact CZ3-CG2 3.43Å; S57-T193 WeakPolarHBondContact CA-OG1 3.44Å; S57-T193 PolarHBondContact OG-OG1 2.98Å; A60-T193 HydrophobicContact CB-CG2 3.72Å; M189-T193 PolarHBondContact O-N 2.89Å; M189-T193 VanDerWaalsContact O-N 3.08Å; M189-T193 PolarHBondContact O-OG1 2.99Å; Y190-T193 PolarHBondContact O-N 2.97Å; T191-T193 PolarHBondContact O-N 2.92Å; T193-Q195 VanDerWaalsContact C-N 3.34Å; T193-Q195 PolarHBondContact O-N 2.9Å; T193-T196 WeakPolarHBondContact O-CB 3.44Å; T193-T196 PolarHBondContact O-N 3.5Å; T193-F197 HydrophobicContact CG2-CD2 4.36Å; T193-F197 HydrophobicContact CG2-CE2 3.78Å; T193-F197 WeakPolarHBondContact O-CD2 3.38Å; T193-F197 PolarHBondContact O-N 3.45Å
194	F	87.8	Confident	88	Confident	62 Å²	62	24.4 Å²	24.4	27%	0.272	13%	0.125	S	C	.	.	H	α-helix	trans	-57.7	-50.5	177	175.5	-101.1	0	0	0	110.9	Y23 M26 V27 Y190 T191 T196 F197 V198	Y23-F194 HydrophobicContact CD2-CE1 4.28Å; Y23-F194 AromaticContact CE2-CE1 3.71Å; Y23-F194 HydrophobicContact CE2-CE1 3.71Å; M26-F194 HydrophobicContact CE-CE1 3.45Å; M26-F194 VanDerWaalsContact CE-CE1 3.45Å; M26-F194 HydrophobicContact CE-CE2 4.2Å; M26-F194 HydrophobicContact CE-CZ 3.15Å; M26-F194 HydrophobicContact CG-CZ 4.45Å; M26-F194 HydrophobicContact SD-CE1 4.08Å; M26-F194 HydrophobicContact SD-CE2 3.98Å; M26-F194 HydrophobicContact SD-CZ 3.48Å; M26-F194 WeakPolarHBondContact SD-CZ 3.3Å; V27-F194 HydrophobicContact CG2-CD1 4.42Å; V27-F194 HydrophobicContact CG2-CE1 4.48Å; Y190-F194 PolarHBondContact O-N 2.97Å; Y190-F194 VanDerWaalsContact O-N 3.17Å; T191-F194 PolarHBondContact O-N 2.91Å; F194-T196 VanDerWaalsContact C-N 3.3Å; F194-T196 PolarHBondContact O-N 3.02Å; F194-F197 PolarHBondContact O-N 3.35Å; F194-V198 HydrophobicContact CD1-CG2 4.37Å; F194-V198 HydrophobicContact CE1-CG2 3.77Å; F194-V198 HydrophobicContact CE2-CG2 4.12Å; F194-V198 HydrophobicContact CZ-CG2 3.59Å; F194-V198 PolarHBondContact O-N 3.46Å
195	Q	88.6	Confident	88.9	Confident	4 Å²	4	26.9 Å²	26.9	2%	0.019	14%	0.14	C	C	.	.	H	α-helix	trans	-59.8	-38.3	-179.6	-174.3	-164.9	-69.6	0	0	112.7	T191 D192 T193 F197 V198 I199 A379 A380 S383	T191-Q195 VanDerWaalsContact O-CB 3.23Å; T191-Q195 WeakPolarHBondContact O-CB 3.11Å; T191-Q195 PolarHBondContact O-N 3.1Å; D192-Q195 PolarHBondContact O-N 3.27Å; T193-Q195 VanDerWaalsContact C-N 3.34Å; T193-Q195 PolarHBondContact O-N 2.9Å; Q195-F197 VanDerWaalsContact C-N 3.32Å; Q195-F197 PolarHBondContact O-N 3.37Å; Q195-V198 PolarHBondContact O-N 2.99Å; Q195-I199 HydrophobicContact CG-CD1 3.75Å; Q195-I199 HydrophobicContact CG-CG1 4.16Å; Q195-I199 WeakPolarHBondContact O-CB 3.09Å; Q195-I199 VanDerWaalsContact O-CG1 3.32Å; Q195-I199 WeakPolarHBondContact O-CG1 3.45Å; Q195-I199 PolarHBondContact O-N 3.16Å; Q195-A379 PolarHBondContact OE1-O 2.98Å; Q195-A379 VanDerWaalsContact OE1-O 3.05Å; Q195-A380 VanDerWaalsContact CD-CA 3.41Å; Q195-S383 VanDerWaalsContact OE1-CB 3.26Å
196	T	91.2	Very high	89.7	Confident	2 Å²	2	26.9 Å²	26.9	1%	0.012	14%	0.14	C	C	.	.	H	α-helix	trans	-55.5	-46.4	177	-63.3	0	0	0	0	111.7	A60 F63 A64 D192 T193 F194 I199 I200 L311	A60-T196 HydrophobicContact CB-CG2 4.07Å; A60-T196 PolarHBondContact O-OG1 3.12Å; A60-T196 VanDerWaalsContact O-OG1 3.11Å; F63-T196 HydrophobicContact CD1-CG2 3.55Å; F63-T196 HydrophobicContact CE1-CG2 4.03Å; F63-T196 HydrophobicContact CG-CG2 4.47Å; A64-T196 WeakPolarHBondContact CB-OG1 3.46Å; D192-T196 WeakPolarHBondContact O-CB 3.15Å; D192-T196 PolarHBondContact O-N 2.6Å; D192-T196 PolarHBondContact O-OG1 2.92Å; T193-T196 WeakPolarHBondContact O-CB 3.44Å; T193-T196 PolarHBondContact O-N 3.5Å; F194-T196 VanDerWaalsContact C-N 3.3Å; F194-T196 PolarHBondContact O-N 3.02Å; T196-I199 PolarHBondContact O-N 2.88Å; T196-I200 HydrophobicContact CG2-CD1 3.67Å; T196-I200 WeakPolarHBondContact O-CB 3.17Å; T196-I200 WeakPolarHBondContact O-CD1 3.23Å; T196-I200 VanDerWaalsContact O-CG1 3.25Å; T196-I200 WeakPolarHBondContact O-CG1 3.47Å; T196-I200 PolarHBondContact O-N 3.29Å; T196-L311 HydrophobicContact CG2-CD1 4.15Å
197	F	90.9	Very high	90.4	Very high	135 Å²	135	27.3 Å²	27.3	59%	0.592	14%	0.142	S	C	*	.	H	α-helix	trans	-64.1	-42.7	179.3	-70.9	-68.4	0	0	0	111.9	T193 F194 Q195 I200 A201	T193-F197 HydrophobicContact CG2-CD2 4.36Å; T193-F197 HydrophobicContact CG2-CE2 3.78Å; T193-F197 WeakPolarHBondContact O-CD2 3.38Å; T193-F197 PolarHBondContact O-N 3.45Å; F194-F197 PolarHBondContact O-N 3.35Å; Q195-F197 VanDerWaalsContact C-N 3.32Å; Q195-F197 PolarHBondContact O-N 3.37Å; F197-I200 PolarHBondContact O-N 3.12Å; F197-A201 WeakPolarHBondContact O-CB 3.23Å; F197-A201 PolarHBondContact O-N 3.41Å
198	V	90.3	Very high	91.1	Very high	25 Å²	25	29.6 Å²	29.6	15%	0.152	17%	0.165	C	C	.	.	H	α-helix	trans	-69.7	-39.9	-179.7	-164.6	0	0	0	0	111.5	Y23 F194 Q195 I200 A201 G202 L372 V376	Y23-V198 HydrophobicContact CE2-CG2 4.48Å; F194-V198 HydrophobicContact CD1-CG2 4.37Å; F194-V198 HydrophobicContact CE1-CG2 3.77Å; F194-V198 HydrophobicContact CE2-CG2 4.12Å; F194-V198 HydrophobicContact CZ-CG2 3.59Å; F194-V198 PolarHBondContact O-N 3.46Å; Q195-V198 PolarHBondContact O-N 2.99Å; V198-I200 PolarHBondContact O-N 3.35Å; V198-A201 PolarHBondContact O-N 2.91Å; V198-G202 PolarHBondContact O-N 3.09Å; V198-L372 HydrophobicContact CG1-CD1 4.38Å; V198-L372 HydrophobicContact CG1-CG 4.45Å; V198-V376 HydrophobicContact CB-CG1 4.23Å; V198-V376 HydrophobicContact CB-CG2 3.95Å; V198-V376 HydrophobicContact CG1-CB 4.37Å; V198-V376 HydrophobicContact CG1-CG1 4.24Å; V198-V376 HydrophobicContact CG1-CG2 3.26Å
199	I	91	Very high	91.7	Very high	3 Å²	3	33.9 Å²	33.9	2%	0.015	18%	0.184	C	C	.	.	H	α-helix	trans	-55.8	-52.4	173.5	-79.6	171.7	0	0	0	110.4	F72 Q195 T196 G202 A203 V376 A380	F72-I199 HydrophobicContact CE2-CG2 4.14Å; F72-I199 HydrophobicContact CZ-CG2 3.69Å; Q195-I199 HydrophobicContact CG-CD1 3.75Å; Q195-I199 HydrophobicContact CG-CG1 4.16Å; Q195-I199 WeakPolarHBondContact O-CB 3.09Å; Q195-I199 VanDerWaalsContact O-CG1 3.32Å; Q195-I199 WeakPolarHBondContact O-CG1 3.45Å; Q195-I199 PolarHBondContact O-N 3.16Å; T196-I199 PolarHBondContact O-N 2.88Å; I199-G202 PolarHBondContact O-N 2.8Å; I199-A203 VanDerWaalsContact O-CB 3.29Å; I199-A203 WeakPolarHBondContact O-CB 3.41Å; I199-A203 PolarHBondContact O-N 3.27Å; I199-V376 HydrophobicContact CB-CG1 4.21Å; I199-V376 HydrophobicContact CG1-CG1 3.36Å; I199-A380 HydrophobicContact CD1-CB 3.72Å
200	I	93.1	Very high	92.1	Very high	23 Å²	23	33.9 Å²	33.9	12%	0.118	18%	0.184	C	C	.	.	H	α-helix	trans	-63	-48.2	-176.1	-70	165.5	0	0	0	109.6	F63 T196 F197 V198 G202 A203 F204 L311 L314	F63-I200 HydrophobicContact CE1-CD1 4.11Å; F63-I200 HydrophobicContact CE1-CG1 4.1Å; F63-I200 HydrophobicContact CZ-CD1 4.47Å; F63-I200 HydrophobicContact CZ-CG1 4.34Å; T196-I200 HydrophobicContact CG2-CD1 3.67Å; T196-I200 WeakPolarHBondContact O-CB 3.17Å; T196-I200 WeakPolarHBondContact O-CD1 3.23Å; T196-I200 VanDerWaalsContact O-CG1 3.25Å; T196-I200 WeakPolarHBondContact O-CG1 3.47Å; T196-I200 PolarHBondContact O-N 3.29Å; F197-I200 PolarHBondContact O-N 3.12Å; V198-I200 PolarHBondContact O-N 3.35Å; I200-G202 PolarHBondContact O-N 2.94Å; I200-A203 PolarHBondContact O-N 3.44Å; I200-F204 HydrophobicContact CG2-CD2 3.61Å; I200-F204 HydrophobicContact CG2-CE2 3.49Å; I200-F204 VanDerWaalsContact CG2-CE2 3.49Å; I200-F204 WeakPolarHBondContact O-CD2 3.39Å; I200-F204 PolarHBondContact O-N 3.33Å; I200-L311 HydrophobicContact CD1-CD1 4.4Å; I200-L311 HydrophobicContact CD1-CD2 3.59Å; I200-L314 HydrophobicContact CD1-CD1 4.48Å; I200-L314 HydrophobicContact CG2-CD1 4.14Å
201	A	93.5	Very high	92.6	Very high	54 Å²	54	32.6 Å²	32.6	45%	0.446	18%	0.18	S	C	.	.	H	α-helix	trans	-59.3	-47.7	177.9	0	0	0	0	0	112	F197 V198 A203 F204 V205	F197-A201 WeakPolarHBondContact O-CB 3.23Å; F197-A201 PolarHBondContact O-N 3.41Å; V198-A201 PolarHBondContact O-N 2.91Å; A201-A203 PolarHBondContact O-N 2.72Å; A201-F204 PolarHBondContact O-N 3.47Å; A201-V205 WeakPolarHBondContact O-CG2 3.46Å; A201-V205 PolarHBondContact O-N 2.99Å
202	G	92.7	Very high	93.1	Very high	14 Å²	14	35 Å²	35	14%	0.144	21%	0.206	C	C	.	.	H	α-helix	trans	-61.8	-40.8	178.2	0	0	0	0	0	112.9	V198 I199 I200 V205 L206 M365	V198-G202 PolarHBondContact O-N 3.09Å; I199-G202 PolarHBondContact O-N 2.8Å; I200-G202 PolarHBondContact O-N 2.94Å; G202-V205 PolarHBondContact O-N 2.81Å; G202-L206 PolarHBondContact O-N 3.01Å; G202-M365 WeakPolarHBondContact O-CE 3.46Å
203	A	93.8	Very high	93.4	Very high	1 Å²	1	40.9 Å²	40.9	1%	0.008	23%	0.234	C	C	.	.	H	α-helix	trans	-70	-35.5	177.7	0	0	0	0	0	112.7	I199 I200 A201 L206 T207 L318	I199-A203 VanDerWaalsContact O-CB 3.29Å; I199-A203 WeakPolarHBondContact O-CB 3.41Å; I199-A203 PolarHBondContact O-N 3.27Å; I200-A203 PolarHBondContact O-N 3.44Å; A201-A203 PolarHBondContact O-N 2.72Å; A203-L206 PolarHBondContact O-N 2.91Å; A203-T207 VanDerWaalsContact O-CB 3.3Å; A203-T207 WeakPolarHBondContact O-CB 3.42Å; A203-T207 PolarHBondContact O-N 3.48Å; A203-T207 PolarHBondContact O-OG1 3.12Å; A203-L318 HydrophobicContact CB-CB 3.98Å; A203-L318 HydrophobicContact CB-CD1 4.17Å
204	F	95.7	Very high	93.7	Very high	105 Å²	105	40.8 Å²	40.8	46%	0.461	23%	0.233	S	C	.	.	H	α-helix	trans	-61.1	-46.2	170.6	-90.1	-69.3	0	0	0	111.7	I200 A201 T207 G208 L314 L318	I200-F204 HydrophobicContact CG2-CD2 3.61Å; I200-F204 HydrophobicContact CG2-CE2 3.49Å; I200-F204 VanDerWaalsContact CG2-CE2 3.49Å; I200-F204 WeakPolarHBondContact O-CD2 3.39Å; I200-F204 PolarHBondContact O-N 3.33Å; A201-F204 PolarHBondContact O-N 3.47Å; F204-T207 PolarHBondContact O-N 2.83Å; F204-G208 PolarHBondContact O-N 3.36Å; F204-L314 HydrophobicContact CE2-CD1 4.41Å; F204-L314 HydrophobicContact CZ-CD2 3.96Å; F204-L318 HydrophobicContact CD1-CD2 3.66Å; F204-L318 HydrophobicContact CD2-CD1 3.93Å; F204-L318 HydrophobicContact CD2-CD2 4.36Å; F204-L318 HydrophobicContact CE1-CD2 3.84Å; F204-L318 HydrophobicContact CE2-CD1 3.82Å; F204-L318 HydrophobicContact CG-CD1 4.31Å; F204-L318 HydrophobicContact CG-CD2 3.93Å; F204-L318 HydrophobicContact CZ-CD1 4.12Å; F204-L318 HydrophobicContact CZ-CD2 4.26Å
205	V	95.4	Very high	94.1	Very high	55 Å²	55	40.8 Å²	40.8	33%	0.333	25%	0.25	S	S	.	.	H	α-helix	trans	-61	-48.7	177.3	172.3	0	0	0	0	110.6	A201 G202 T207 G208 F209 M365 L369	A201-V205 WeakPolarHBondContact O-CG2 3.46Å; A201-V205 PolarHBondContact O-N 2.99Å; G202-V205 PolarHBondContact O-N 2.81Å; V205-T207 VanDerWaalsContact C-N 3.32Å; V205-T207 PolarHBondContact O-N 2.99Å; V205-G208 PolarHBondContact O-N 3.13Å; V205-F209 HydrophobicContact CG1-CD2 3.75Å; V205-F209 HydrophobicContact CG1-CE2 3.62Å; V205-F209 VanDerWaalsContact O-CD2 3.3Å; V205-F209 WeakPolarHBondContact O-CD2 3.35Å; V205-F209 PolarHBondContact O-N 3.47Å; V205-F209 VanDerWaalsContact O-N 3.07Å; V205-M365 HydrophobicContact CG1-CE 4.32Å; V205-L369 HydrophobicContact CG1-CD1 4.08Å
206	L	95.2	Very high	94.4	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-56.6	-47.2	176.9	-174.6	66.7	0	0	0	111.8	G202 A203 G208 F209 S210 Y357 L360 V361 M365	G202-L206 PolarHBondContact O-N 3.01Å; A203-L206 PolarHBondContact O-N 2.91Å; L206-G208 VanDerWaalsContact C-N 3.31Å; L206-G208 PolarHBondContact O-N 3.24Å; L206-F209 PolarHBondContact O-N 3.35Å; L206-S210 VanDerWaalsContact O-CB 3.29Å; L206-S210 WeakPolarHBondContact O-CB 3.46Å; L206-S210 PolarHBondContact O-N 3.01Å; L206-S210 PolarHBondContact O-OG 3.13Å; L206-Y357 HydrophobicContact CD2-CD1 4.34Å; L206-Y357 HydrophobicContact CD2-CD2 4.34Å; L206-Y357 HydrophobicContact CD2-CE1 3.68Å; L206-Y357 HydrophobicContact CD2-CE2 3.67Å; L206-Y357 WeakPolarHBondContact CD2-OH 3.38Å; L206-L360 HydrophobicContact CD1-CB 4.26Å; L206-L360 HydrophobicContact CD2-CB 4.49Å; L206-V361 HydrophobicContact CD1-CG2 4.24Å; L206-V361 HydrophobicContact CD2-CG2 3.72Å; L206-M365 HydrophobicContact CB-CE 3.57Å; L206-M365 HydrophobicContact CD1-CE 3.92Å; L206-M365 HydrophobicContact CD1-CG 3.58Å; L206-M365 HydrophobicContact CD1-SD 3.98Å; L206-M365 HydrophobicContact CG-CE 4.32Å
207	T	96.1	Very high	94.6	Very high	14 Å²	14	47.1 Å²	47.1	9%	0.086	28%	0.282	C	S	.	.	H	α-helix	trans	-61.2	-42.6	-179.1	-58.8	0	0	0	0	110.6	A203 F204 V205 S210 F211 F317 P322	A203-T207 VanDerWaalsContact O-CB 3.3Å; A203-T207 WeakPolarHBondContact O-CB 3.42Å; A203-T207 PolarHBondContact O-N 3.48Å; A203-T207 PolarHBondContact O-OG1 3.12Å; F204-T207 PolarHBondContact O-N 2.83Å; V205-T207 VanDerWaalsContact C-N 3.32Å; V205-T207 PolarHBondContact O-N 2.99Å; T207-S210 PolarHBondContact O-N 3.05Å; T207-F211 HydrophobicContact CG2-CD2 3.65Å; T207-F211 HydrophobicContact CG2-CE2 3.57Å; T207-F211 VanDerWaalsContact O-CD2 3.28Å; T207-F211 WeakPolarHBondContact O-CD2 3.47Å; T207-F211 PolarHBondContact O-N 3.47Å; T207-F317 WeakPolarHBondContact CG2-O 3.11Å; T207-P322 HydrophobicContact CG2-CG 4.36Å; T207-P322 WeakPolarHBondContact OG1-CG 3.41Å
208	G	96.2	Very high	94.8	Very high	49 Å²	49	45.1 Å²	45.1	51%	0.505	29%	0.285	S	S	.	.	H	α-helix	trans	-58.6	-50.8	175.4	0	0	0	0	0	113	F204 V205 L206 F211 G212	F204-G208 PolarHBondContact O-N 3.36Å; V205-G208 PolarHBondContact O-N 3.13Å; L206-G208 VanDerWaalsContact C-N 3.31Å; L206-G208 PolarHBondContact O-N 3.24Å; G208-F211 PolarHBondContact O-N 3.22Å; G208-G212 PolarHBondContact O-N 3.12Å; G208-G212 VanDerWaalsContact O-N 3.08Å
209	F	96.1	Very high	95.1	Very high	90 Å²	90	44.6 Å²	44.6	40%	0.395	28%	0.283	S	S	.	.	H	α-helix	trans	-62.8	-42.5	175.8	-78.5	-75.4	0	0	0	112.2	V205 L206 F211 G212 E213 V364 P366 L369	V205-F209 HydrophobicContact CG1-CD2 3.75Å; V205-F209 HydrophobicContact CG1-CE2 3.62Å; V205-F209 VanDerWaalsContact O-CD2 3.3Å; V205-F209 WeakPolarHBondContact O-CD2 3.35Å; V205-F209 PolarHBondContact O-N 3.47Å; V205-F209 VanDerWaalsContact O-N 3.07Å; L206-F209 PolarHBondContact O-N 3.35Å; F209-F211 PolarHBondContact O-N 2.78Å; F209-G212 WeakPolarHBondContact O-CA 3.39Å; F209-G212 PolarHBondContact O-N 3.25Å; F209-E213 PolarHBondContact O-N 3.15Å; F209-V364 HydrophobicContact CB-CG1 3.66Å; F209-P366 HydrophobicContact CE2-CG 4.49Å; F209-P366 HydrophobicContact CZ-CG 4.22Å; F209-L369 HydrophobicContact CE2-CD1 4.45Å
210	S	96.4	Very high	95.3	Very high	0 Å²	0	44.4 Å²	44.4	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-60.2	-43.7	-179.9	-58.6	0	0	0	0	111.9	L206 T207 G212 E213 I214	L206-S210 VanDerWaalsContact O-CB 3.29Å; L206-S210 WeakPolarHBondContact O-CB 3.46Å; L206-S210 PolarHBondContact O-N 3.01Å; L206-S210 PolarHBondContact O-OG 3.13Å; T207-S210 PolarHBondContact O-N 3.05Å; S210-G212 VanDerWaalsContact C-N 3.32Å; S210-E213 PolarHBondContact O-N 3.37Å; S210-I214 PolarHBondContact O-N 2.94Å
211	F	97.3	Very high	95.4	Very high	40 Å²	40	46.3 Å²	46.3	18%	0.175	29%	0.292	C	S	.	.	H	α-helix	trans	-67.7	-32.9	174.1	-84.7	-67.3	0	0	0	112.7	T207 G208 F209 I214 G215 G216 Y217 L220 F321 I325	T207-F211 HydrophobicContact CG2-CD2 3.65Å; T207-F211 HydrophobicContact CG2-CE2 3.57Å; T207-F211 VanDerWaalsContact O-CD2 3.28Å; T207-F211 WeakPolarHBondContact O-CD2 3.47Å; T207-F211 PolarHBondContact O-N 3.47Å; G208-F211 PolarHBondContact O-N 3.22Å; F209-F211 PolarHBondContact O-N 2.78Å; F211-I214 HydrophobicContact CD1-CD1 4.05Å; F211-I214 HydrophobicContact CD1-CG1 4.47Å; F211-I214 HydrophobicContact CE1-CD1 4.42Å; F211-G215 PolarHBondContact O-N 3.45Å; F211-G215 VanDerWaalsContact O-N 3.14Å; F211-G216 PolarHBondContact O-N 3.23Å; F211-Y217 HydrophobicContact CE1-CD2 4.19Å; F211-Y217 HydrophobicContact CZ-CD2 4.37Å; F211-L220 HydrophobicContact CE1-CB 4.25Å; F211-L220 HydrophobicContact CE1-CD2 3.81Å; F211-L220 HydrophobicContact CZ-CD2 4.01Å; F211-F321 HydrophobicContact CE2-CB 4.38Å; F211-F321 HydrophobicContact CE2-CD2 4.25Å; F211-F321 HydrophobicContact CZ-CB 4.1Å; F211-F321 AromaticContact CZ-CD2 3.78Å; F211-F321 HydrophobicContact CZ-CD2 3.78Å; F211-F321 HydrophobicContact CZ-CG 4.25Å; F211-I325 HydrophobicContact CD1-CD1 3.9Å; F211-I325 HydrophobicContact CD2-CD1 4.11Å; F211-I325 HydrophobicContact CE1-CD1 3.89Å; F211-I325 HydrophobicContact CE2-CD1 4.09Å; F211-I325 HydrophobicContact CG-CD1 4.01Å; F211-I325 HydrophobicContact CZ-CD1 3.98Å
212	G	96.3	Very high	95.5	Very high	56 Å²	56	48.3 Å²	48.3	58%	0.577	30%	0.298	S	S	*	.	H	α-helix	trans	-58	-47.7	173.2	0	0	0	0	0	112.4	G208 F209 S210 I214 G215	G208-G212 PolarHBondContact O-N 3.12Å; G208-G212 VanDerWaalsContact O-N 3.08Å; F209-G212 WeakPolarHBondContact O-CA 3.39Å; F209-G212 PolarHBondContact O-N 3.25Å; S210-G212 VanDerWaalsContact C-N 3.32Å; G212-I214 PolarHBondContact O-N 3.28Å; G212-G215 PolarHBondContact O-N 3.21Å
213	E	95.4	Very high	95.7	Very high	122 Å²	122	51.8 Å²	51.8	57%	0.57	31%	0.31	S	S	*	.	H	α-helix	trans	-60.7	-39.6	-179.3	-72	-61	139.7	0	0	113.4	F209 S210 L329 V364	F209-E213 PolarHBondContact O-N 3.15Å; S210-E213 PolarHBondContact O-N 3.37Å; E213-L329 HydrophobicContact CB-CD1 3.99Å; E213-L329 HydrophobicContact CB-CD2 4.25Å; E213-L329 HydrophobicContact CG-CD1 4.48Å; E213-V364 HydrophobicContact CG-CG1 4.03Å; E213-V364 HydrophobicContact CG-CG2 4.47Å
214	I	95.7	Very high	95.8	Very high	3 Å²	3	51.8 Å²	51.8	2%	0.015	31%	0.309	C	S	.	.	H	α-helix	trans	-86.6	-15.3	-178.3	58.4	156.3	0	0	0	113.9	S210 F211 G212 G216 A219 L220 K223 I325 I328 L329	S210-I214 PolarHBondContact O-N 2.94Å; F211-I214 HydrophobicContact CD1-CD1 4.05Å; F211-I214 HydrophobicContact CD1-CG1 4.47Å; F211-I214 HydrophobicContact CE1-CD1 4.42Å; G212-I214 PolarHBondContact O-N 3.28Å; I214-G216 WeakPolarHBondContact CD1-O 3.46Å; I214-A219 WeakPolarHBondContact O-CB 2.99Å; I214-L220 HydrophobicContact CD1-CB 3.7Å; I214-L220 HydrophobicContact CD1-CD1 4.39Å; I214-K223 PolarHBondContact O-NZ 3.5Å; I214-I325 HydrophobicContact CD1-CD1 4.11Å; I214-I325 HydrophobicContact CD1-CG1 3.78Å; I214-I325 HydrophobicContact CG1-CG1 4.5Å; I214-I325 HydrophobicContact CG1-CG2 4.47Å; I214-I325 HydrophobicContact CG2-CG2 3.76Å; I214-I328 HydrophobicContact CG2-CB 4.44Å; I214-I328 HydrophobicContact CG2-CG2 3.97Å; I214-L329 HydrophobicContact CG2-CD2 3.79Å; I214-L329 HydrophobicContact CG2-CG 4.07Å
215	G	94.4	Very high	95.7	Very high	61 Å²	61	51.4 Å²	51.4	63%	0.629	31%	0.306	S	S	*	.	T	Hydrogen-bonded Turn	trans	91	27.6	-175.7	0	0	0	0	0	114.7	F211 G212	F211-G215 PolarHBondContact O-N 3.45Å; F211-G215 VanDerWaalsContact O-N 3.14Å; G212-G215 PolarHBondContact O-N 3.21Å
216	G	95.4	Very high	95.7	Very high	23 Å²	23	52.9 Å²	52.9	24%	0.237	32%	0.318	C	S	.	.	S	Bend	trans	94.4	-175.1	172.4	0	0	0	0	0	115.9	F211 I214 S218 A219 L220	F211-G216 PolarHBondContact O-N 3.23Å; I214-G216 WeakPolarHBondContact CD1-O 3.46Å; G216-S218 PolarHBondContact O-N 3.08Å; G216-A219 WeakPolarHBondContact O-CB 3.35Å; G216-A219 PolarHBondContact O-N 2.98Å; G216-L220 PolarHBondContact O-N 2.92Å
217	Y	95.3	Very high	95.6	Very high	117 Å²	117	53 Å²	53	46%	0.459	32%	0.32	S	S	.	.	H	α-helix	trans	-65	-37.9	-173.2	-177.8	-103.5	0	0	0	113.7	F211 A219 L220 L221 F321	F211-Y217 HydrophobicContact CE1-CD2 4.19Å; F211-Y217 HydrophobicContact CZ-CD2 4.37Å; Y217-A219 PolarHBondContact O-N 3.34Å; Y217-L220 HydrophobicContact CD2-CD2 4.2Å; Y217-L220 HydrophobicContact CE2-CD2 4.32Å; Y217-L220 VanDerWaalsContact O-CB 3.29Å; Y217-L220 WeakPolarHBondContact O-CB 3.42Å; Y217-L220 PolarHBondContact O-N 3.32Å; Y217-L221 HydrophobicContact CD1-CD1 4.24Å; Y217-L221 HydrophobicContact CD1-CG 4.48Å; Y217-L221 HydrophobicContact CE1-CD1 3.73Å; Y217-L221 HydrophobicContact CE1-CD2 4.32Å; Y217-L221 HydrophobicContact CE1-CG 4.05Å; Y217-L221 PolarHBondContact O-N 3Å; Y217-F321 HydrophobicContact CD2-CE2 4.38Å; Y217-F321 AromaticContact CE2-CE2 3.94Å; Y217-F321 HydrophobicContact CE2-CE2 3.94Å; Y217-F321 AromaticContact CE2-CZ 3.88Å; Y217-F321 HydrophobicContact CE2-CZ 3.88Å
218	S	95.6	Very high	95.4	Very high	93 Å²	93	55.6 Å²	55.6	65%	0.65	33%	0.332	S	S	*	.	H	α-helix	trans	-61.9	-34.2	176.3	-53	0	0	0	0	112	G216 L221 T222	G216-S218 PolarHBondContact O-N 3.08Å; S218-L221 PolarHBondContact O-N 3.19Å; S218-T222 PolarHBondContact O-N 2.97Å; S218-T222 PolarHBondContact O-OG1 3.03Å
219	A	95.9	Very high	95.1	Very high	13 Å²	13	53.4 Å²	53.4	11%	0.107	31%	0.309	C	S	.	.	H	α-helix	trans	-72.2	-31.9	175	0	0	0	0	0	112.2	I214 G216 Y217 T222 K223	I214-A219 WeakPolarHBondContact O-CB 2.99Å; G216-A219 WeakPolarHBondContact O-CB 3.35Å; G216-A219 PolarHBondContact O-N 2.98Å; Y217-A219 PolarHBondContact O-N 3.34Å; A219-T222 PolarHBondContact O-N 3.48Å; A219-T222 PolarHBondContact O-OG1 3.45Å; A219-K223 HydrophobicContact CB-CD 4.21Å; A219-K223 WeakPolarHBondContact O-CB 3.31Å; A219-K223 WeakPolarHBondContact O-CG 3.46Å; A219-K223 PolarHBondContact O-N 3.27Å
220	L	96.6	Very high	94.7	Very high	0 Å²	0	53 Å²	53	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-59.7	-47.3	172.5	177.7	60.4	0	0	0	110.6	F211 I214 G216 Y217 T222 Y224 F254 F321 M324 I325 I328	F211-L220 HydrophobicContact CE1-CB 4.25Å; F211-L220 HydrophobicContact CE1-CD2 3.81Å; F211-L220 HydrophobicContact CZ-CD2 4.01Å; I214-L220 HydrophobicContact CD1-CB 3.7Å; I214-L220 HydrophobicContact CD1-CD1 4.39Å; G216-L220 PolarHBondContact O-N 2.92Å; Y217-L220 HydrophobicContact CD2-CD2 4.2Å; Y217-L220 HydrophobicContact CE2-CD2 4.32Å; Y217-L220 VanDerWaalsContact O-CB 3.29Å; Y217-L220 WeakPolarHBondContact O-CB 3.42Å; Y217-L220 PolarHBondContact O-N 3.32Å; L220-T222 VanDerWaalsContact C-N 3.34Å; L220-T222 PolarHBondContact O-N 3.5Å; L220-Y224 WeakPolarHBondContact O-CB 3.13Å; L220-Y224 PolarHBondContact O-N 3.25Å; L220-Y224 VanDerWaalsContact O-N 3.15Å; L220-F254 HydrophobicContact CG-CE1 4.4Å; L220-F254 HydrophobicContact CG-CZ 4.29Å; L220-F321 HydrophobicContact CD2-CB 4.45Å; L220-F321 HydrophobicContact CD2-CD1 4.24Å; L220-F321 HydrophobicContact CD2-CG 4.19Å; L220-M324 HydrophobicContact CD1-CB 3.9Å; L220-I325 HydrophobicContact CD1-CG1 3.82Å; L220-I328 HydrophobicContact CD1-CD1 3.59Å
221	L	94.9	Very high	94.1	Very high	62 Å²	62	57.7 Å²	57.7	33%	0.325	34%	0.342	S	S	.	.	H	α-helix	trans	-62.1	-39.3	-179.4	-65.5	179.1	0	0	0	112.9	Y217 S218 Y225 F254	Y217-L221 HydrophobicContact CD1-CD1 4.24Å; Y217-L221 HydrophobicContact CD1-CG 4.48Å; Y217-L221 HydrophobicContact CE1-CD1 3.73Å; Y217-L221 HydrophobicContact CE1-CD2 4.32Å; Y217-L221 HydrophobicContact CE1-CG 4.05Å; Y217-L221 PolarHBondContact O-N 3Å; S218-L221 PolarHBondContact O-N 3.19Å; L221-Y225 WeakPolarHBondContact O-CD2 3.44Å; L221-Y225 WeakPolarHBondContact O-CE2 3.28Å; L221-F254 HydrophobicContact CD2-CD1 3.57Å; L221-F254 HydrophobicContact CD2-CD2 4.15Å; L221-F254 HydrophobicContact CD2-CE1 3.47Å; L221-F254 VanDerWaalsContact CD2-CE1 3.47Å; L221-F254 HydrophobicContact CD2-CE2 4.05Å; L221-F254 HydrophobicContact CD2-CG 3.92Å; L221-F254 HydrophobicContact CD2-CZ 3.72Å
222	T	94.5	Very high	93.3	Very high	96 Å²	96	60.2 Å²	60.2	59%	0.589	35%	0.353	S	S	*	.	H	α-helix	trans	-85.8	-48.5	-176.5	54.3	0	0	0	0	112.4	S218 A219 L220 Y224	S218-T222 PolarHBondContact O-N 2.97Å; S218-T222 PolarHBondContact O-OG1 3.03Å; A219-T222 PolarHBondContact O-N 3.48Å; A219-T222 PolarHBondContact O-OG1 3.45Å; L220-T222 VanDerWaalsContact C-N 3.34Å; L220-T222 PolarHBondContact O-N 3.5Å; T222-Y224 VanDerWaalsContact C-N 3.34Å; T222-Y224 PolarHBondContact O-N 2.88Å
223	K	96.5	Very high	92.4	Very high	88 Å²	88	61.6 Å²	61.6	38%	0.383	35%	0.354	S	S	.	.	H	α-helix	trans	-72.9	-25	-174.9	-63.8	-179.4	175.4	175.2	0	113.2	I214 A219 Y225 S226 A227 I328	I214-K223 PolarHBondContact O-NZ 3.5Å; A219-K223 HydrophobicContact CB-CD 4.21Å; A219-K223 WeakPolarHBondContact O-CB 3.31Å; A219-K223 WeakPolarHBondContact O-CG 3.46Å; A219-K223 PolarHBondContact O-N 3.27Å; K223-Y225 VanDerWaalsContact C-N 3.29Å; K223-Y225 PolarHBondContact O-N 3.22Å; K223-S226 WeakPolarHBondContact CA-OG 3.49Å; K223-S226 PolarHBondContact O-N 3.06Å; K223-S226 VanDerWaalsContact O-N 3.12Å; K223-S226 PolarHBondContact O-OG 3.05Å; K223-A227 PolarHBondContact O-N 2.93Å; K223-I328 HydrophobicContact CB-CD1 4.1Å; K223-I328 HydrophobicContact CB-CG1 4.35Å; K223-I328 HydrophobicContact CB-CG2 3.79Å; K223-I328 HydrophobicContact CD-CG2 4.21Å
224	Y	96.4	Very high	91.3	Very high	0 Å²	0	56.2 Å²	56.2	0%	0	33%	0.33	C	S	.	.	G	3₁₀ helix	trans	-58.6	-42.2	178.8	-175.4	-101.1	0	0	0	111.6	A80 G83 L220 T222 S226 A227 P249 A253 F254 M324 I328	A80-Y224 PolarHBondContact O-OH 2.98Å; G83-Y224 PolarHBondContact N-OH 3.01Å; L220-Y224 WeakPolarHBondContact O-CB 3.13Å; L220-Y224 PolarHBondContact O-N 3.25Å; L220-Y224 VanDerWaalsContact O-N 3.15Å; T222-Y224 VanDerWaalsContact C-N 3.34Å; T222-Y224 PolarHBondContact O-N 2.88Å; Y224-S226 VanDerWaalsContact C-N 3.26Å; Y224-S226 PolarHBondContact O-N 3.26Å; Y224-A227 VanDerWaalsContact O-CB 3.26Å; Y224-A227 WeakPolarHBondContact O-CB 3.46Å; Y224-A227 PolarHBondContact O-N 3.01Å; Y224-A227 VanDerWaalsContact O-N 3.14Å; Y224-P249 HydrophobicContact CD1-CB 4.05Å; Y224-P249 HydrophobicContact CE1-CB 3.66Å; Y224-P249 WeakPolarHBondContact O-CG 3.18Å; Y224-A253 HydrophobicContact CD1-CB 4.01Å; Y224-A253 HydrophobicContact CE1-CB 3.43Å; Y224-A253 VanDerWaalsContact CE1-CB 3.43Å; Y224-F254 HydrophobicContact CD1-CE2 4.01Å; Y224-F254 HydrophobicContact CD1-CZ 4.39Å; Y224-F254 HydrophobicContact CG-CE2 4.33Å; Y224-F254 HydrophobicContact CG-CZ 4.33Å; Y224-M324 HydrophobicContact CD1-CE 3.91Å; Y224-M324 HydrophobicContact CD2-CB 3.9Å; Y224-M324 HydrophobicContact CD2-CE 3.79Å; Y224-M324 HydrophobicContact CD2-CG 4.35Å; Y224-M324 HydrophobicContact CE1-CE 3.93Å; Y224-M324 HydrophobicContact CE2-CB 3.84Å; Y224-M324 HydrophobicContact CE2-CE 3.8Å; Y224-M324 HydrophobicContact CE2-CG 3.92Å; Y224-M324 HydrophobicContact CG-CE 3.84Å; Y224-I328 HydrophobicContact CD2-CG1 4.39Å
225	Y	94.9	Very high	90	Very high	98 Å²	98	64.2 Å²	64.2	38%	0.384	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-68	-24.1	179.1	-67.4	-69.6	0	0	0	113.8	L221 K223 R250 Q251 F254	L221-Y225 WeakPolarHBondContact O-CD2 3.44Å; L221-Y225 WeakPolarHBondContact O-CE2 3.28Å; K223-Y225 VanDerWaalsContact C-N 3.29Å; K223-Y225 PolarHBondContact O-N 3.22Å; Y225-R250 WeakPolarHBondContact CE1-O 3.34Å; Y225-Q251 PolarHBondContact OH-O 3.42Å; Y225-F254 HydrophobicContact CE2-CD2 4.02Å; Y225-F254 AromaticContact CE2-CE2 3.97Å; Y225-F254 HydrophobicContact CE2-CE2 3.97Å; Y225-F254 AromaticContact CZ-CD2 3.93Å
226	S	93.6	Very high	88.8	Confident	85 Å²	85	64.5 Å²	64.5	59%	0.594	36%	0.359	S	S	*	.	G	3₁₀ helix	trans	-89.4	0.8	174.7	54.9	0	0	0	0	114.1	K223 Y224 I228	K223-S226 WeakPolarHBondContact CA-OG 3.49Å; K223-S226 PolarHBondContact O-N 3.06Å; K223-S226 VanDerWaalsContact O-N 3.12Å; K223-S226 PolarHBondContact O-OG 3.05Å; Y224-S226 VanDerWaalsContact C-N 3.26Å; Y224-S226 PolarHBondContact O-N 3.26Å; S226-I228 PolarHBondContact O-N 3.17Å
227	A	93.7	Very high	87.5	Confident	4 Å²	4	68.2 Å²	68.2	3%	0.033	38%	0.378	C	S	.	.			trans	-79.4	67.5	-176.4	0	0	0	0	0	112.1	K223 Y224 R327 I328	K223-A227 PolarHBondContact O-N 2.93Å; Y224-A227 VanDerWaalsContact O-CB 3.26Å; Y224-A227 WeakPolarHBondContact O-CB 3.46Å; Y224-A227 PolarHBondContact O-N 3.01Å; Y224-A227 VanDerWaalsContact O-N 3.14Å; A227-R327 HydrophobicContact CB-CG 3.98Å; A227-R327 PolarHBondContact O-NE 3.42Å; A227-I328 HydrophobicContact CB-CG1 4.15Å
228	I	92.1	Very high	86	Confident	67 Å²	67	71.6 Å²	71.6	34%	0.344	40%	0.397	S	S	.	.			trans	-106.9	133.6	-176.9	-60.9	170.3	0	0	0	109.1	S226 Y247 T248	S226-I228 PolarHBondContact O-N 3.17Å; I228-Y247 HydrophobicContact CG2-CD2 3.74Å; I228-Y247 HydrophobicContact CG2-CE2 4.27Å; I228-T248 HydrophobicContact CD1-CG2 4.23Å
229	P	90.5	Very high	84.7	Confident	4 Å²	4	75.5 Å²	75.5	3%	0.026	40%	0.398	C	S	.	.			trans	-64.2	146.1	174	29	-38.1	0	0	0	111.8	N231 N332 G335 V337	P229-N231 VanDerWaalsContact C-N 3.33Å; P229-N332 WeakPolarHBondContact CA-OD1 3.42Å; P229-G335 WeakPolarHBondContact CG-O 3.1Å; P229-V337 HydrophobicContact CG-CG2 4.48Å
230	S	87.9	Confident	83.5	Confident	82 Å²	82	76.1 Å²	76.1	57%	0.573	40%	0.398	S	S	*	.	S	Bend	trans	-68.7	-32.1	177.5	-50.9	0	0	0	0	112.7	N332	S230-N332 PolarHBondContact N-OD1 3.39Å; S230-N332 PolarHBondContact OG-ND2 3.23Å; S230-N332 PolarHBondContact OG-OD1 3.47Å
231	N	82.8	Confident	82.5	Confident	97 Å²	97	83.3 Å²	83.3	52%	0.519	44%	0.436	S	S	.	.			trans	-105.7	117.6	179	-66.5	-26.7	0	0	0	110	P229 V338 I341	P229-N231 VanDerWaalsContact C-N 3.33Å; N231-V338 HydrophobicContact CB-CG2 4.46Å; N231-V338 WeakPolarHBondContact O-CG2 3.39Å; N231-I341 HydrophobicContact CB-CD1 3.58Å; N231-I341 WeakPolarHBondContact ND2-CD1 3.4Å
232	F	81.2	Confident	81.9	Confident	93 Å²	93	81.5 Å²	81.5	41%	0.408	43%	0.427	S	S	.	.			trans	-132.3	0.6	-179.6	49.5	-98.1	0	0	0	113.4	Y247 V337	F232-Y247 HydrophobicContact CB-CD1 3.71Å; F232-Y247 HydrophobicContact CB-CE1 3.79Å; F232-Y247 HydrophobicContact CB-CG 4.21Å; F232-Y247 HydrophobicContact CD2-CE1 4.43Å; F232-Y247 HydrophobicContact CG-CE1 4.21Å; F232-V337 HydrophobicContact CB-CG2 4.46Å
233	S	76.7	Confident	81.3	Confident	85 Å²	85	79.5 Å²	79.5	59%	0.594	42%	0.416	S	S	*	.			trans	-113	127	176	-58.6	0	0	0	0	109.6
234	S	72.3	Confident	80.8	Confident	9 Å²	9	78.3 Å²	78.3	6%	0.063	42%	0.419	C	S	.	.			trans	-73.7	156.5	173	58.2	0	0	0	0	111.2	D236 T237	S234-D236 VanDerWaalsContact C-N 3.25Å; S234-D236 PolarHBondContact OG-O 3.03Å; S234-T237 WeakPolarHBondContact O-CG2 3.38Å
235	L	69.3	Low	80.2	Confident	171 Å²	171	85.8 Å²	85.8	90%	0.895	45%	0.454	S	S	*	.	S	Bend	trans	-68	-28	170.8	-79.6	145.3	0	0	0	112
236	D	69	Low	79.7	Confident	67 Å²	67	82.1 Å²	82.1	36%	0.358	44%	0.442	S	S	.	.			trans	-103.5	81.7	172.8	-170.8	-9.2	0	0	0	110	S234 Q238 R239 Y240	S234-D236 VanDerWaalsContact C-N 3.25Å; S234-D236 PolarHBondContact OG-O 3.03Å; D236-Q238 PolarHBondContact O-N 3.43Å; D236-Q238 PolarHBondContact OD1-N 3.36Å; D236-R239 HydrophobicContact CB-CB 4.26Å; D236-R239 PolarHBondContact O-N 3.33Å; D236-R239 WeakPolarHBondContact OD1-CB 3.34Å; D236-R239 PolarHBondContact OD1-N 3.15Å; D236-R239 VanDerWaalsContact OD1-N 3.1Å; D236-R239 VanDerWaalsContact OD2-CB 3.25Å; D236-R239 WeakPolarHBondContact OD2-CB 3.49Å; D236-Y240 HydrophobicContact CB-CD2 4.34Å; D236-Y240 HydrophobicContact CB-CE2 4.38Å; D236-Y240 WeakPolarHBondContact O-CD2 3.35Å; D236-Y240 PolarHBondContact O-N 2.81Å
237	T	67.6	Low	79.3	Confident	102 Å²	102	80.2 Å²	80.2	63%	0.626	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.6	-15.1	179.5	55.6	0	0	0	0	113.2	S234	S234-T237 WeakPolarHBondContact O-CG2 3.38Å
238	Q	63.8	Low	79.2	Confident	187 Å²	187	82.5 Å²	82.5	87%	0.874	44%	0.436	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.4	-32.5	175.8	-72.6	-87.3	-31	0	0	111	D236	D236-Q238 PolarHBondContact O-N 3.43Å; D236-Q238 PolarHBondContact OD1-N 3.36Å
239	R	68.6	Low	79.2	Confident	176 Å²	176	79.8 Å²	79.8	66%	0.664	42%	0.423	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.3	-30.9	-180	-169.6	173.3	179.5	137.6	2	114.1	D236	D236-R239 HydrophobicContact CB-CB 4.26Å; D236-R239 PolarHBondContact O-N 3.33Å; D236-R239 WeakPolarHBondContact OD1-CB 3.34Å; D236-R239 PolarHBondContact OD1-N 3.15Å; D236-R239 VanDerWaalsContact OD1-N 3.1Å; D236-R239 VanDerWaalsContact OD2-CB 3.25Å; D236-R239 WeakPolarHBondContact OD2-CB 3.49Å
240	Y	71.4	Confident	79.2	Confident	26 Å²	26	83 Å²	83	10%	0.102	43%	0.434	C	S	.	.			trans	-126.1	111.9	-174.9	-48.8	-67.2	0	0	0	112	D236 P339 E340 I503 F504	D236-Y240 HydrophobicContact CB-CD2 4.34Å; D236-Y240 HydrophobicContact CB-CE2 4.38Å; D236-Y240 WeakPolarHBondContact O-CD2 3.35Å; D236-Y240 PolarHBondContact O-N 2.81Å; Y240-P339 HydrophobicContact CD1-CG 4.09Å; Y240-P339 HydrophobicContact CD2-CG 4.34Å; Y240-P339 HydrophobicContact CE1-CG 4.08Å; Y240-P339 HydrophobicContact CE2-CG 4.3Å; Y240-P339 HydrophobicContact CG-CG 4.23Å; Y240-E340 WeakPolarHBondContact CE2-OE1 2.96Å; Y240-I503 HydrophobicContact CD1-CG2 4.09Å; Y240-F504 HydrophobicContact CD1-CE1 4.13Å; Y240-F504 HydrophobicContact CD1-CZ 4.22Å; Y240-F504 AromaticContact CE1-CE1 3.77Å; Y240-F504 HydrophobicContact CE1-CE1 3.77Å; Y240-F504 AromaticContact CE1-CZ 3.67Å; Y240-F504 HydrophobicContact CE1-CZ 3.67Å
241	N	75.4	Confident	79.4	Confident	151 Å²	151	87.4 Å²	87.4	81%	0.807	45%	0.446	S	S	*	.			trans	-102.9	88.9	172.1	-175.1	5.6	0	0	0	109.8	S243	N241-S243 PolarHBondContact O-N 3.26Å
242	I	81.3	Confident	79.9	Confident	24 Å²	24	85 Å²	85	12%	0.123	43%	0.433	C	S	.	.			trans	-81.5	109.3	-175.9	-56.3	171.7	0	0	0	109.4	C246 Y247 V337 V338	I242-C246 HydrophobicContact CG2-CB 4Å; I242-Y247 HydrophobicContact CG2-CD1 4.23Å; I242-V337 HydrophobicContact CD1-CG2 4.46Å; I242-V337 HydrophobicContact CG2-CB 4.29Å; I242-V337 HydrophobicContact CG2-CG2 4.05Å; I242-V338 HydrophobicContact CD1-CG2 4.29Å
243	S	83.3	Confident	80.4	Confident	53 Å²	53	80.5 Å²	80.5	37%	0.371	41%	0.413	S	S	.	.			trans	-67.2	149.5	174.7	177.7	0	0	0	0	111.5	N241 Q245 C246	N241-S243 PolarHBondContact O-N 3.26Å; S243-Q245 PolarHBondContact O-N 3.18Å; S243-Q245 VanDerWaalsContact O-N 3.16Å; S243-C246 VanDerWaalsContact O-CB 3.29Å; S243-C246 WeakPolarHBondContact O-CB 3.37Å; S243-C246 PolarHBondContact O-N 2.94Å; S243-C246 PolarHBondContact O-SG 3.26Å
244	S	84.1	Confident	81.3	Confident	63 Å²	63	78.6 Å²	78.6	44%	0.441	39%	0.394	S	S	.	.	H	α-helix	trans	-57.2	-32.5	177.7	58.9	0	0	0	0	113.7	C246 Y247 T248	S244-C246 PolarHBondContact O-N 3.23Å; S244-C246 VanDerWaalsContact O-N 3.1Å; S244-Y247 VanDerWaalsContact CA-CE1 3.44Å; S244-Y247 VanDerWaalsContact CA-CZ 3.48Å; S244-Y247 WeakPolarHBondContact CB-OH 3.34Å; S244-Y247 PolarHBondContact O-N 3.08Å; S244-T248 WeakPolarHBondContact O-CG2 3.38Å; S244-T248 PolarHBondContact O-N 3.14Å; S244-T248 VanDerWaalsContact O-N 3.14Å; S244-T248 PolarHBondContact O-OG1 2.96Å
245	Q	84.9	Confident	82.3	Confident	158 Å²	158	80.4 Å²	80.4	74%	0.738	41%	0.407	S	S	*	.	H	α-helix	trans	-59.9	-22.1	177.5	-64.5	176.8	-4.9	0	0	113.4	S243	S243-Q245 PolarHBondContact O-N 3.18Å; S243-Q245 VanDerWaalsContact O-N 3.16Å
246	C	83.9	Confident	83.4	Confident	20 Å²	20	74.4 Å²	74.4	14%	0.135	38%	0.376	C	S	.	.	H	α-helix	trans	-75.9	-35.7	-176.6	-50.4	0	0	0	0	112.3	I242 S243 S244 V337 C502	I242-C246 HydrophobicContact CG2-CB 4Å; S243-C246 VanDerWaalsContact O-CB 3.29Å; S243-C246 WeakPolarHBondContact O-CB 3.37Å; S243-C246 PolarHBondContact O-N 2.94Å; S243-C246 PolarHBondContact O-SG 3.26Å; S244-C246 PolarHBondContact O-N 3.23Å; S244-C246 VanDerWaalsContact O-N 3.1Å; C246-V337 HydrophobicContact CB-CG1 4.33Å; C246-V337 WeakPolarHBondContact O-CG1 3.49Å; C246-C502 HydrophobicContact CB-CB 3.81Å; C246-C502 VanDerWaalsContact SG-CB 3.58Å; C246-C502 PolarHBondContact SG-O 3.25Å; C246-C502 VanDerWaalsContact SG-O 3.33Å
247	Y	86.5	Confident	84.5	Confident	45 Å²	45	75.9 Å²	75.9	18%	0.176	38%	0.383	C	S	.	.	H	α-helix	trans	-103.4	-22.7	-175.5	57.1	-106.6	0	0	0	113.3	I228 F232 I242 S244 R327 V337	I228-Y247 HydrophobicContact CG2-CD2 3.74Å; I228-Y247 HydrophobicContact CG2-CE2 4.27Å; F232-Y247 HydrophobicContact CB-CD1 3.71Å; F232-Y247 HydrophobicContact CB-CE1 3.79Å; F232-Y247 HydrophobicContact CB-CG 4.21Å; F232-Y247 HydrophobicContact CD2-CE1 4.43Å; F232-Y247 HydrophobicContact CG-CE1 4.21Å; I242-Y247 HydrophobicContact CG2-CD1 4.23Å; S244-Y247 VanDerWaalsContact CA-CE1 3.44Å; S244-Y247 VanDerWaalsContact CA-CZ 3.48Å; S244-Y247 WeakPolarHBondContact CB-OH 3.34Å; S244-Y247 PolarHBondContact O-N 3.08Å; Y247-R327 PolarHBondContact O-NH2 3.14Å; Y247-V337 HydrophobicContact CD1-CG2 4.44Å
248	T	90.4	Very high	85.7	Confident	52 Å²	52	71.3 Å²	71.3	32%	0.319	35%	0.354	S	S	.	.	S	Bend	trans	-79.6	131.3	176.4	57.8	0	0	0	0	111.2	I228 S244	I228-T248 HydrophobicContact CD1-CG2 4.23Å; S244-T248 WeakPolarHBondContact O-CG2 3.38Å; S244-T248 PolarHBondContact O-N 3.14Å; S244-T248 VanDerWaalsContact O-N 3.14Å; S244-T248 PolarHBondContact O-OG1 2.96Å
249	P	92.5	Very high	87.1	Confident	10 Å²	10	66.1 Å²	66.1	7%	0.065	33%	0.332	C	S	.	.	P	Polyproline II helix	trans	-54.9	143.4	168.5	-21.6	30.8	0	0	0	111.7	Y224	Y224-P249 HydrophobicContact CD1-CB 4.05Å; Y224-P249 HydrophobicContact CE1-CB 3.66Å; Y224-P249 WeakPolarHBondContact O-CG 3.18Å
250	R	90.7	Very high	88.1	Confident	72 Å²	72	60.1 Å²	60.1	27%	0.272	32%	0.316	S	S	.	.	P	Polyproline II helix	trans	-64.3	142.9	179.6	-72.6	-174.9	63.3	132	2.5	111.9	Y225 D252 A253 D264	Y225-R250 WeakPolarHBondContact CE1-O 3.34Å; R250-D252 VanDerWaalsContact C-N 3.33Å; R250-D252 WeakPolarHBondContact CB-OD1 3.25Å; R250-D252 IonicContact CZ-OD1 3.23Å; R250-D252 IonicContact CZ-OD2 2.63Å; R250-D252 IonicContact NE-OD1 3.47Å; R250-D252 PolarHBondContact NE-OD1 2.91Å; R250-D252 IonicContact NE-OD2 3.94Å; R250-D252 IonicContact NH2-OD1 3.47Å; R250-D252 PolarHBondContact NH2-OD1 3.47Å; R250-D252 IonicContact NH2-OD2 3.71Å; R250-D252 PolarHBondContact NH2-OD2 3.41Å; R250-D252 PolarHBondContact O-N 3.39Å; R250-A253 WeakPolarHBondContact O-CB 3.41Å; R250-A253 PolarHBondContact O-N 2.87Å; R250-D264 IonicContact CZ-OD1 2.56Å; R250-D264 IonicContact NE-OD1 3.56Å; R250-D264 VanDerWaalsContact NH1-CB 3.29Å; R250-D264 IonicContact NH1-OD1 3.38Å; R250-D264 PolarHBondContact NH1-OD1 3.31Å; R250-D264 VanDerWaalsContact NH1-OD1 3.11Å; R250-D264 IonicContact NH1-OD2 3.22Å; R250-D264 IonicContact NH2-OD1 3.82Å
251	Q	91	Very high	88.7	Confident	175 Å²	175	64.6 Å²	64.6	82%	0.818	35%	0.347	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.5	-36	177.1	-67.3	-165.3	-7.8	0	0	112.7	Y225 A253	Y225-Q251 PolarHBondContact OH-O 3.42Å; Q251-A253 VanDerWaalsContact C-N 3.26Å; Q251-A253 PolarHBondContact O-N 3.15Å
252	D	93	Very high	89.1	Confident	45 Å²	45	63 Å²	63	24%	0.241	34%	0.342	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.9	21.9	177.1	63.9	-20.5	0	0	0	113.4	R250 F254 S255 R258	R250-D252 VanDerWaalsContact C-N 3.33Å; R250-D252 WeakPolarHBondContact CB-OD1 3.25Å; R250-D252 IonicContact CZ-OD1 3.23Å; R250-D252 IonicContact CZ-OD2 2.63Å; R250-D252 IonicContact NE-OD1 3.47Å; R250-D252 PolarHBondContact NE-OD1 2.91Å; R250-D252 IonicContact NE-OD2 3.94Å; R250-D252 IonicContact NH2-OD1 3.47Å; R250-D252 PolarHBondContact NH2-OD1 3.47Å; R250-D252 IonicContact NH2-OD2 3.71Å; R250-D252 PolarHBondContact NH2-OD2 3.41Å; R250-D252 PolarHBondContact O-N 3.39Å; D252-F254 PolarHBondContact O-N 2.81Å; D252-S255 PolarHBondContact O-N 3.42Å; D252-R258 PolarHBondContact O-NE 3.27Å; D252-R258 PolarHBondContact O-NH2 2.8Å; D252-R258 WeakPolarHBondContact OD2-CD 3.31Å; D252-R258 IonicContact OD2-NE 2.78Å
253	A	93.2	Very high	89.3	Confident	0 Å²	0	62.1 Å²	62.1	0%	0	34%	0.339	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-33.2	-179.8	0	0	0	0	0	113.6	G83 I84 Y224 R250 Q251 R258	G83-A253 CarbonylContact C-O 3.45Å; G83-A253 WeakPolarHBondContact CA-O 3.41Å; I84-A253 PolarHBondContact N-O 3.29Å; Y224-A253 HydrophobicContact CD1-CB 4.01Å; Y224-A253 HydrophobicContact CE1-CB 3.43Å; Y224-A253 VanDerWaalsContact CE1-CB 3.43Å; R250-A253 WeakPolarHBondContact O-CB 3.41Å; R250-A253 PolarHBondContact O-N 2.87Å; Q251-A253 VanDerWaalsContact C-N 3.26Å; Q251-A253 PolarHBondContact O-N 3.15Å; A253-R258 PolarHBondContact O-NH2 3.11Å
254	F	95.2	Very high	89.4	Confident	44 Å²	44	61.7 Å²	61.7	19%	0.193	33%	0.333	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96.6	12.4	177.5	-65.6	-81.7	0	0	0	113.9	I84 L220 L221 Y224 Y225 D252 M324	I84-F254 HydrophobicContact CD1-CB 4.49Å; I84-F254 WeakPolarHBondContact CD1-O 3.33Å; I84-F254 HydrophobicContact CG2-CD1 3.87Å; I84-F254 HydrophobicContact CG2-CE1 4.29Å; L220-F254 HydrophobicContact CG-CE1 4.4Å; L220-F254 HydrophobicContact CG-CZ 4.29Å; L221-F254 HydrophobicContact CD2-CD1 3.57Å; L221-F254 HydrophobicContact CD2-CD2 4.15Å; L221-F254 HydrophobicContact CD2-CE1 3.47Å; L221-F254 VanDerWaalsContact CD2-CE1 3.47Å; L221-F254 HydrophobicContact CD2-CE2 4.05Å; L221-F254 HydrophobicContact CD2-CG 3.92Å; L221-F254 HydrophobicContact CD2-CZ 3.72Å; Y224-F254 HydrophobicContact CD1-CE2 4.01Å; Y224-F254 HydrophobicContact CD1-CZ 4.39Å; Y224-F254 HydrophobicContact CG-CE2 4.33Å; Y224-F254 HydrophobicContact CG-CZ 4.33Å; Y225-F254 HydrophobicContact CE2-CD2 4.02Å; Y225-F254 AromaticContact CE2-CE2 3.97Å; Y225-F254 HydrophobicContact CE2-CE2 3.97Å; Y225-F254 AromaticContact CZ-CD2 3.93Å; D252-F254 PolarHBondContact O-N 2.81Å; F254-M324 HydrophobicContact CD1-CE 4.13Å; F254-M324 HydrophobicContact CE1-CE 3.38Å; F254-M324 HydrophobicContact CE1-SD 4.26Å; F254-M324 HydrophobicContact CE2-CE 3.99Å; F254-M324 HydrophobicContact CZ-CE 3.3Å
255	S	94	Very high	89.7	Confident	47 Å²	47	58.8 Å²	58.8	33%	0.329	31%	0.312	S	S	.	.			trans	-98	125.2	169.9	-169.1	0	0	0	0	110.7	D252 L257 R258	D252-S255 PolarHBondContact O-N 3.42Å; S255-L257 PolarHBondContact OG-O 3.46Å; S255-R258 PolarHBondContact O-NE 3.18Å
256	L	90.8	Very high	90	Very high	46 Å²	46	51.3 Å²	51.3	24%	0.241	28%	0.277	C	S	.	.	S	Bend	trans	-75.2	-37.1	174.4	-166.1	78.1	0	0	0	111.6	W91 M316	W91-L256 HydrophobicContact CE3-CD2 3.95Å; W91-L256 HydrophobicContact CZ3-CD2 3.99Å; L256-M316 HydrophobicContact CD1-CE 3.84Å
257	L	92.8	Very high	90.4	Very high	98 Å²	98	55.5 Å²	55.5	51%	0.513	29%	0.29	S	S	.	.	S	Bend	trans	-104.4	101.3	178.6	-57.6	-179	0	0	0	108.2	S255 W267 V270	S255-L257 PolarHBondContact OG-O 3.46Å; L257-W267 HydrophobicContact CB-CB 3.83Å; L257-W267 HydrophobicContact CD2-CB 4.03Å; L257-W267 HydrophobicContact CG-CB 4.45Å; L257-V270 HydrophobicContact CD2-CG1 4.32Å
258	R	92.7	Very high	90.7	Very high	6 Å²	6	54.4 Å²	54.4	2%	0.023	29%	0.289	C	S	.	.	B	Isolated β-bridge	trans	-92	169	-178.1	-62.3	-175.2	171	161.4	4.1	112	A82 A85 D252 A253 S255 D264 W267	A82-R258 PolarHBondContact O-NH1 3.45Å; A82-R258 PolarHBondContact O-NH2 3.22Å; A85-R258 HydrophobicContact CB-CG 4.41Å; D252-R258 PolarHBondContact O-NE 3.27Å; D252-R258 PolarHBondContact O-NH2 2.8Å; D252-R258 WeakPolarHBondContact OD2-CD 3.31Å; D252-R258 IonicContact OD2-NE 2.78Å; A253-R258 PolarHBondContact O-NH2 3.11Å; S255-R258 PolarHBondContact O-NE 3.18Å; R258-D264 WeakPolarHBondContact CD-OD1 3.23Å; R258-D264 IonicContact CZ-OD1 3.84Å; R258-D264 IonicContact NE-OD1 3.77Å; R258-D264 IonicContact NH1-OD1 2.97Å; R258-D264 PolarHBondContact NH1-OD1 3.03Å; R258-D264 IonicContact NH1-OD2 3.14Å; R258-D264 PolarHBondContact NH1-OD2 2.84Å; R258-W267 WeakPolarHBondContact O-CB 3.41Å; R258-W267 PolarHBondContact O-N 3.36Å
259	D	92.8	Very high	90.8	Very high	77 Å²	77	52 Å²	52	41%	0.412	27%	0.274	S	S	.	.			trans	-46	134.3	177.2	-174.1	-85	0	0	0	111.6	T261 V262 G263 P266	D259-T261 PolarHBondContact O-N 2.85Å; D259-T261 VanDerWaalsContact O-N 3.14Å; D259-T261 WeakPolarHBondContact OD1-CA 3.38Å; D259-T261 PolarHBondContact OD1-N 3.43Å; D259-T261 PolarHBondContact OD1-OG1 3.27Å; D259-V262 HydrophobicContact CB-CB 4.47Å; D259-V262 PolarHBondContact OD1-N 2.68Å; D259-G263 WeakPolarHBondContact O-CA 3.38Å; D259-G263 PolarHBondContact O-N 3.01Å; D259-P266 WeakPolarHBondContact O-CA 3.16Å; D259-P266 WeakPolarHBondContact O-CB 2.9Å
260	P	89.9	Confident	90.7	Very high	50 Å²	50	51.9 Å²	51.9	33%	0.325	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-16.6	-175.1	25.3	-35.5	0	0	0	114.6	P266 P268 H519	P260-P266 WeakPolarHBondContact O-CB 3.44Å; P260-P268 HydrophobicContact CB-CG 3.81Å; P260-H519 PolarHBondContact O-CE1 3.22Å; P260-H519 VanDerWaalsContact O-CE1 3.24Å
261	T	85.3	Confident	90.7	Very high	121 Å²	121	51.2 Å²	51.2	74%	0.742	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-124.3	-39	-172.5	55.5	0	0	0	0	113.7	D259	D259-T261 PolarHBondContact O-N 2.85Å; D259-T261 VanDerWaalsContact O-N 3.14Å; D259-T261 WeakPolarHBondContact OD1-CA 3.38Å; D259-T261 PolarHBondContact OD1-N 3.43Å; D259-T261 PolarHBondContact OD1-OG1 3.27Å
262	V	83.1	Confident	90.9	Very high	116 Å²	116	48.4 Å²	48.4	70%	0.703	26%	0.262	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.2	-13.7	-176.5	-171.2	0	0	0	0	111.7	D259	D259-V262 HydrophobicContact CB-CB 4.47Å; D259-V262 PolarHBondContact OD1-N 2.68Å
263	G	84.4	Confident	90.9	Very high	6 Å²	6	46.3 Å²	46.3	6%	0.062	25%	0.251	C	S	.	.			trans	-62.4	139.5	174	0	0	0	0	0	112	D259 L265 P266	D259-G263 WeakPolarHBondContact O-CA 3.38Å; D259-G263 PolarHBondContact O-N 3.01Å; G263-L265 VanDerWaalsContact C-N 3.29Å; G263-P266 WeakPolarHBondContact O-CD 3.47Å
264	D	86.3	Confident	90.8	Very high	45 Å²	45	46.7 Å²	46.7	24%	0.241	25%	0.253	C	S	.	.	S	Bend	trans	-67.5	-31.9	165.9	58.3	-25	0	0	0	111.8	A82 R250 R258 H516	A82-D264 WeakPolarHBondContact CB-OD2 3.31Å; R250-D264 IonicContact CZ-OD1 2.56Å; R250-D264 IonicContact NE-OD1 3.56Å; R250-D264 VanDerWaalsContact NH1-CB 3.29Å; R250-D264 IonicContact NH1-OD1 3.38Å; R250-D264 PolarHBondContact NH1-OD1 3.31Å; R250-D264 VanDerWaalsContact NH1-OD1 3.11Å; R250-D264 IonicContact NH1-OD2 3.22Å; R250-D264 IonicContact NH2-OD1 3.82Å; R258-D264 WeakPolarHBondContact CD-OD1 3.23Å; R258-D264 IonicContact CZ-OD1 3.84Å; R258-D264 IonicContact NE-OD1 3.77Å; R258-D264 IonicContact NH1-OD1 2.97Å; R258-D264 PolarHBondContact NH1-OD1 3.03Å; R258-D264 IonicContact NH1-OD2 3.14Å; R258-D264 PolarHBondContact NH1-OD2 2.84Å; D264-H516 PolarHBondContact O-CE1 3.26Å; D264-H516 PolarHBondContact O-NE2 3.13Å
265	L	90.3	Very high	90.8	Very high	2 Å²	2	46.6 Å²	46.6	1%	0.01	26%	0.256	C	S	.	.	S	Bend	trans	-122.6	78.3	170	-68.8	177	0	0	0	108.3	A85 V86 F89 G263 W267 V270 Y517 L518	A85-L265 HydrophobicContact CB-CB 4.22Å; A85-L265 HydrophobicContact CB-CD1 3.89Å; V86-L265 HydrophobicContact CB-CD1 4.15Å; F89-L265 HydrophobicContact CE2-CD1 4.4Å; F89-L265 HydrophobicContact CE2-CD2 3.88Å; F89-L265 HydrophobicContact CZ-CD2 4.4Å; G263-L265 VanDerWaalsContact C-N 3.29Å; L265-W267 PolarHBondContact O-N 3.31Å; L265-V270 HydrophobicContact CB-CG2 3.95Å; L265-V270 WeakPolarHBondContact O-CG2 3.46Å; L265-Y517 WeakPolarHBondContact CD2-OH 3.4Å; L265-L518 HydrophobicContact CD2-CD1 4.16Å
266	P	92.4	Very high	90.8	Very high	1 Å²	1	45 Å²	45	1%	0.006	24%	0.244	C	C	.	.	B	Isolated β-bridge	trans	-66.8	135.1	-173.5	27.2	-33.9	0	0	0	110.5	D259 P260 G263 P268 G269 V270 H516 H519	D259-P266 WeakPolarHBondContact O-CA 3.16Å; D259-P266 WeakPolarHBondContact O-CB 2.9Å; P260-P266 WeakPolarHBondContact O-CB 3.44Å; G263-P266 WeakPolarHBondContact O-CD 3.47Å; P266-P268 VanDerWaalsContact O-N 3.17Å; P266-G269 CarbonylContact O-C 3.57Å; P266-G269 WeakPolarHBondContact O-CA 3.42Å; P266-G269 PolarHBondContact O-N 3.4Å; P266-V270 WeakPolarHBondContact O-CG2 3.14Å; P266-V270 PolarHBondContact O-N 3.29Å; P266-H516 HydrophobicContact CG-CB 4.4Å; P266-H519 WeakPolarHBondContact CG-CE1 3.32Å
267	W	92.2	Very high	90.9	Very high	107 Å²	107	43.7 Å²	43.7	41%	0.405	24%	0.241	S	C	.	.	H	α-helix	trans	-55.6	-36.1	-170.9	80.5	-98.7	0	0	0	115.3	L257 R258 L265 V270 V271 F272	L257-W267 HydrophobicContact CB-CB 3.83Å; L257-W267 HydrophobicContact CD2-CB 4.03Å; L257-W267 HydrophobicContact CG-CB 4.45Å; R258-W267 WeakPolarHBondContact O-CB 3.41Å; R258-W267 PolarHBondContact O-N 3.36Å; L265-W267 PolarHBondContact O-N 3.31Å; W267-V270 WeakPolarHBondContact O-CB 3.11Å; W267-V270 PolarHBondContact O-N 3.25Å; W267-V271 HydrophobicContact CE3-CG2 4.24Å; W267-V271 WeakPolarHBondContact O-CG2 3.47Å; W267-V271 PolarHBondContact O-N 2.83Å; W267-F272 HydrophobicContact CZ3-CE2 4.44Å
268	P	92.9	Very high	91	Very high	23 Å²	23	39.4 Å²	39.4	15%	0.149	22%	0.221	C	C	.	.	H	α-helix	trans	-68.2	-39.9	177.2	-16.1	30.8	0	0	0	111.2	P260 P266 V270 V271 F272	P260-P268 HydrophobicContact CB-CG 3.81Å; P266-P268 VanDerWaalsContact O-N 3.17Å; P268-V270 VanDerWaalsContact C-N 3.31Å; P268-V270 PolarHBondContact O-N 3.35Å; P268-V271 PolarHBondContact O-N 3.31Å; P268-F272 WeakPolarHBondContact O-CB 3.42Å; P268-F272 WeakPolarHBondContact O-CD2 3.46Å; P268-F272 PolarHBondContact O-N 2.67Å
269	G	91.4	Very high	91.1	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.223	C	C	.	.	I	π-helix	trans	-61.5	-40.9	172	0	0	0	0	0	112	P266 G273 M274	P266-G269 CarbonylContact O-C 3.57Å; P266-G269 WeakPolarHBondContact O-CA 3.42Å; P266-G269 PolarHBondContact O-N 3.4Å; G269-G273 CarbonylContact O-C 3.52Å; G269-G273 WeakPolarHBondContact O-CA 3.21Å; G269-G273 PolarHBondContact O-N 3.31Å; G269-M274 PolarHBondContact O-N 2.78Å
270	V	90.4	Very high	91.2	Very high	8 Å²	8	36.8 Å²	36.8	5%	0.048	21%	0.206	C	C	.	.	I	π-helix	trans	-62.2	-44.7	177.2	163.7	0	0	0	0	111.4	L257 L265 P266 W267 P268 M274	L257-V270 HydrophobicContact CD2-CG1 4.32Å; L265-V270 HydrophobicContact CB-CG2 3.95Å; L265-V270 WeakPolarHBondContact O-CG2 3.46Å; P266-V270 WeakPolarHBondContact O-CG2 3.14Å; P266-V270 PolarHBondContact O-N 3.29Å; W267-V270 WeakPolarHBondContact O-CB 3.11Å; W267-V270 PolarHBondContact O-N 3.25Å; P268-V270 VanDerWaalsContact C-N 3.31Å; P268-V270 PolarHBondContact O-N 3.35Å; V270-M274 HydrophobicContact CB-CE 3.4Å; V270-M274 HydrophobicContact CG1-CE 3.22Å; V270-M274 HydrophobicContact CG2-CE 3.51Å; V270-M274 VanDerWaalsContact O-CB 3.29Å; V270-M274 WeakPolarHBondContact O-CB 3.14Å; V270-M274 WeakPolarHBondContact O-CE 3.48Å
271	V	91.5	Very high	91.3	Very high	59 Å²	59	36.2 Å²	36.2	36%	0.358	20%	0.198	S	C	.	.	I	π-helix	trans	-77.7	-49	-177	173.5	0	0	0	0	111.6	W267 P268 T275	W267-V271 HydrophobicContact CE3-CG2 4.24Å; W267-V271 WeakPolarHBondContact O-CG2 3.47Å; W267-V271 PolarHBondContact O-N 2.83Å; P268-V271 PolarHBondContact O-N 3.31Å; V271-T275 WeakPolarHBondContact O-CB 3.19Å; V271-T275 PolarHBondContact O-OG1 3.2Å
272	F	93.4	Very high	91.8	Very high	116 Å²	116	30.7 Å²	30.7	51%	0.509	16%	0.164	S	C	.	.	I	π-helix	trans	-97.4	-47	-171.3	-59.4	-70.8	0	0	0	112.8	W267 P268 T275 I276 I522	W267-F272 HydrophobicContact CZ3-CE2 4.44Å; P268-F272 WeakPolarHBondContact O-CB 3.42Å; P268-F272 WeakPolarHBondContact O-CD2 3.46Å; P268-F272 PolarHBondContact O-N 2.67Å; F272-T275 PolarHBondContact O-N 3.42Å; F272-I276 WeakPolarHBondContact O-CG1 3.33Å; F272-I276 PolarHBondContact O-N 3.25Å; F272-I276 VanDerWaalsContact O-N 3.13Å; F272-I522 HydrophobicContact CB-CD1 3.67Å; F272-I522 HydrophobicContact CB-CG1 4Å
273	G	93	Very high	92.4	Very high	1 Å²	1	25.2 Å²	25.2	1%	0.01	13%	0.13	C	C	.	.	I	π-helix	trans	-62.8	-46.4	-179	0	0	0	0	0	112.1	G269 T275 I276 G277	G269-G273 CarbonylContact O-C 3.52Å; G269-G273 WeakPolarHBondContact O-CA 3.21Å; G269-G273 PolarHBondContact O-N 3.31Å; G273-T275 VanDerWaalsContact C-N 3.34Å; G273-T275 PolarHBondContact O-N 2.67Å; G273-I276 WeakPolarHBondContact O-CB 3.2Å; G273-I276 PolarHBondContact O-N 2.83Å; G273-G277 PolarHBondContact O-N 2.94Å; G273-G277 VanDerWaalsContact O-N 3.1Å
274	M	91.9	Very high	92.8	Very high	8 Å²	8	25.3 Å²	25.3	4%	0.039	13%	0.13	C	C	.	.	H	α-helix	trans	-65.8	-35.3	176.1	-65.9	-159.8	-113.3	0	0	113	F89 G269 V270 I276 G277 G278 L518	F89-M274 WeakPolarHBondContact CA-SD 3.32Å; F89-M274 HydrophobicContact CB-SD 3.91Å; F89-M274 HydrophobicContact CD1-CG 3.95Å; F89-M274 HydrophobicContact CD1-SD 3.23Å; F89-M274 WeakPolarHBondContact CD1-SD 3.45Å; F89-M274 HydrophobicContact CD2-CE 4.13Å; F89-M274 HydrophobicContact CD2-SD 3.46Å; F89-M274 WeakPolarHBondContact CD2-SD 3.44Å; F89-M274 HydrophobicContact CE1-CG 3.67Å; F89-M274 HydrophobicContact CE1-SD 3.46Å; F89-M274 WeakPolarHBondContact CE1-SD 3.37Å; F89-M274 HydrophobicContact CE2-CE 4.23Å; F89-M274 HydrophobicContact CE2-SD 3.69Å; F89-M274 HydrophobicContact CG-CE 4.4Å; F89-M274 HydrophobicContact CG-CG 4.49Å; F89-M274 HydrophobicContact CG-SD 3.23Å; F89-M274 WeakPolarHBondContact CG-SD 3.35Å; F89-M274 HydrophobicContact CZ-CG 4Å; F89-M274 HydrophobicContact CZ-SD 3.68Å; G269-M274 PolarHBondContact O-N 2.78Å; V270-M274 HydrophobicContact CB-CE 3.4Å; V270-M274 HydrophobicContact CG1-CE 3.22Å; V270-M274 HydrophobicContact CG2-CE 3.51Å; V270-M274 VanDerWaalsContact O-CB 3.29Å; V270-M274 WeakPolarHBondContact O-CB 3.14Å; V270-M274 WeakPolarHBondContact O-CE 3.48Å; M274-I276 VanDerWaalsContact C-N 3.29Å; M274-I276 PolarHBondContact O-N 2.89Å; M274-G277 PolarHBondContact O-N 3.27Å; M274-G278 PolarHBondContact O-N 3.25Å; M274-L518 HydrophobicContact CG-CD1 4.25Å; M274-L518 HydrophobicContact CG-CD2 3.89Å
275	T	94.5	Very high	93.1	Very high	42 Å²	42	23.5 Å²	23.5	26%	0.258	12%	0.12	S	C	.	.	H	α-helix	trans	-63.2	-37.9	176	-76.1	0	0	0	0	111.7	N92 I96 V271 F272 G273 G278 I279	N92-T275 PolarHBondContact ND2-OG1 3.46Å; N92-T275 WeakPolarHBondContact OD1-CA 3.44Å; N92-T275 PolarHBondContact OD1-OG1 2.75Å; N92-T275 VanDerWaalsContact OD1-OG1 3.09Å; I96-T275 HydrophobicContact CD1-CG2 3.82Å; V271-T275 WeakPolarHBondContact O-CB 3.19Å; V271-T275 PolarHBondContact O-OG1 3.2Å; F272-T275 PolarHBondContact O-N 3.42Å; G273-T275 VanDerWaalsContact C-N 3.34Å; G273-T275 PolarHBondContact O-N 2.67Å; T275-G278 PolarHBondContact O-N 2.86Å; T275-I279 HydrophobicContact CG2-CD1 4.15Å; T275-I279 VanDerWaalsContact O-CG1 3.3Å; T275-I279 WeakPolarHBondContact O-CG1 3.42Å; T275-I279 PolarHBondContact O-N 3.44Å
276	I	95.4	Very high	93.2	Very high	13 Å²	13	23.6 Å²	23.6	7%	0.067	12%	0.121	C	C	.	.	H	α-helix	trans	-63.2	-49	173.6	-68.2	159.9	0	0	0	110.8	F272 G273 M274 G278 I279 W280 P456 A459 I522 F525	F272-I276 WeakPolarHBondContact O-CG1 3.33Å; F272-I276 PolarHBondContact O-N 3.25Å; F272-I276 VanDerWaalsContact O-N 3.13Å; G273-I276 WeakPolarHBondContact O-CB 3.2Å; G273-I276 PolarHBondContact O-N 2.83Å; M274-I276 VanDerWaalsContact C-N 3.29Å; M274-I276 PolarHBondContact O-N 2.89Å; I276-G278 VanDerWaalsContact C-N 3.27Å; I276-G278 PolarHBondContact O-N 2.94Å; I276-I279 PolarHBondContact O-N 3.36Å; I276-W280 PolarHBondContact O-N 3.48Å; I276-P456 HydrophobicContact CG2-CB 3.85Å; I276-P456 HydrophobicContact CG2-CG 4.2Å; I276-A459 HydrophobicContact CG2-CB 4.24Å; I276-I522 HydrophobicContact CD1-CB 4.36Å; I276-I522 HydrophobicContact CD1-CG1 4.09Å; I276-F525 HydrophobicContact CD1-CB 3.72Å; I276-F525 HydrophobicContact CD1-CD1 4.05Å; I276-F525 HydrophobicContact CD1-CD2 4.42Å; I276-F525 HydrophobicContact CD1-CG 3.82Å; I276-F525 HydrophobicContact CG1-CB 4.31Å; I276-F525 HydrophobicContact CG1-CD1 4.33Å; I276-F525 HydrophobicContact CG1-CD2 4.12Å; I276-F525 HydrophobicContact CG1-CG 4Å; I276-F525 HydrophobicContact CG2-CB 3.97Å; I276-F525 HydrophobicContact CG2-CD2 3.63Å; I276-F525 HydrophobicContact CG2-CE2 4.42Å; I276-F525 HydrophobicContact CG2-CG 4.01Å
277	G	92.8	Very high	93.2	Very high	18 Å²	18	23.6 Å²	23.6	19%	0.186	12%	0.121	C	C	.	.	H	α-helix	trans	-60	-39.3	175.7	0	0	0	0	0	112.2	G273 M274 W280 Y281	G273-G277 PolarHBondContact O-N 2.94Å; G273-G277 VanDerWaalsContact O-N 3.1Å; M274-G277 PolarHBondContact O-N 3.27Å; G277-W280 PolarHBondContact O-N 2.8Å; G277-Y281 WeakPolarHBondContact O-CB 3.35Å; G277-Y281 PolarHBondContact O-N 3.11Å
278	G	93.9	Very high	93.3	Very high	9 Å²	9	18.5 Å²	18.5	9%	0.093	10%	0.102	C	C	.	.	H	α-helix	trans	-62.7	-42.9	175.2	0	0	0	0	0	112.3	I96 M274 T275 I276 W280 Y281 W282	I96-G278 WeakPolarHBondContact CG2-O 3.47Å; M274-G278 PolarHBondContact O-N 3.25Å; T275-G278 PolarHBondContact O-N 2.86Å; I276-G278 VanDerWaalsContact C-N 3.27Å; I276-G278 PolarHBondContact O-N 2.94Å; G278-W280 VanDerWaalsContact C-N 3.31Å; G278-W280 PolarHBondContact O-N 3.36Å; G278-Y281 PolarHBondContact O-N 2.99Å; G278-W282 WeakPolarHBondContact O-CB 3.01Å; G278-W282 VanDerWaalsContact O-CD1 3.27Å; G278-W282 PolarHBondContact O-N 2.68Å
279	I	95	Very high	93.4	Very high	13 Å²	13	17.4 Å²	17.4	7%	0.067	10%	0.095	C	C	.	.	I	π-helix	trans	-59.8	-45.1	176.7	-72.8	162.8	0	0	0	109.9	I96 L99 F104 T275 I276 C283 S284 A459	I96-I279 HydrophobicContact CG2-CG1 4.23Å; L99-I279 HydrophobicContact CD2-CG1 4.25Å; F104-I279 HydrophobicContact CZ-CG2 4.35Å; T275-I279 HydrophobicContact CG2-CD1 4.15Å; T275-I279 VanDerWaalsContact O-CG1 3.3Å; T275-I279 WeakPolarHBondContact O-CG1 3.42Å; T275-I279 PolarHBondContact O-N 3.44Å; I276-I279 PolarHBondContact O-N 3.36Å; I279-C283 HydrophobicContact CG2-CB 4.48Å; I279-C283 WeakPolarHBondContact O-CA 3.18Å; I279-C283 WeakPolarHBondContact O-CB 3.35Å; I279-C283 PolarHBondContact O-N 2.86Å; I279-S284 PolarHBondContact O-N 3.01Å; I279-A459 HydrophobicContact CB-CB 4.47Å; I279-A459 HydrophobicContact CG2-CB 4.16Å
280	W	94.4	Very high	93.3	Very high	14 Å²	14	17.4 Å²	17.4	5%	0.053	10%	0.095	C	C	.	.	I	π-helix	trans	-60.5	-53.7	173.9	166	81	0	0	0	111.6	L140 I276 G277 G278 W282 S284 D285 A459	L140-W280 HydrophobicContact CD1-CZ2 3.95Å; I276-W280 PolarHBondContact O-N 3.48Å; G277-W280 PolarHBondContact O-N 2.8Å; G278-W280 VanDerWaalsContact C-N 3.31Å; G278-W280 PolarHBondContact O-N 3.36Å; W280-W282 PolarHBondContact O-N 3.41Å; W280-S284 CarbonylContact O-C 3.59Å; W280-S284 WeakPolarHBondContact O-CA 3.41Å; W280-S284 WeakPolarHBondContact O-CB 3.29Å; W280-S284 PolarHBondContact O-N 2.74Å; W280-D285 PolarHBondContact O-N 3.45Å; W280-A459 HydrophobicContact CB-CB 4.05Å
281	Y	93.6	Very high	93.4	Very high	38 Å²	38	17.1 Å²	17.1	15%	0.149	9%	0.092	C	C	.	.	I	π-helix	trans	-63.4	-44.8	-173	-177.2	-88	0	0	0	112.8	N66 G277 G278 D285 I288	N66-Y281 VanDerWaalsContact CA-OH 3.27Å; N66-Y281 WeakPolarHBondContact CA-OH 3.39Å; N66-Y281 HydrophobicContact CB-CE1 4.15Å; N66-Y281 VanDerWaalsContact CB-OH 3.28Å; N66-Y281 WeakPolarHBondContact CB-OH 3.28Å; N66-Y281 VanDerWaalsContact ND2-CE1 3.3Å; N66-Y281 WeakPolarHBondContact ND2-CE1 3.35Å; N66-Y281 PolarHBondContact ND2-OH 3.07Å; G277-Y281 WeakPolarHBondContact O-CB 3.35Å; G277-Y281 PolarHBondContact O-N 3.11Å; G278-Y281 PolarHBondContact O-N 2.99Å; Y281-D285 WeakPolarHBondContact O-CB 3.26Å; Y281-I288 HydrophobicContact CD1-CG1 4.36Å; Y281-I288 HydrophobicContact CE1-CD1 3.97Å; Y281-I288 HydrophobicContact CE1-CG1 3.91Å; Y281-I288 WeakPolarHBondContact O-CG1 3.42Å
282	W	95.5	Very high	93.4	Very high	6 Å²	6	14.3 Å²	14.3	2%	0.023	8%	0.075	C	C	.	.	I	π-helix	trans	-87.4	-40.1	-176.1	-67.6	101.7	0	0	0	112.4	N66 A93 I96 V97 L100 G278 W280 I288 K312	N66-W282 HydrophobicContact CB-CH2 3.91Å; N66-W282 HydrophobicContact CB-CZ2 4.33Å; A93-W282 HydrophobicContact CB-CZ2 3.88Å; I96-W282 HydrophobicContact CB-CG 4.44Å; I96-W282 HydrophobicContact CG2-CB 3.91Å; I96-W282 HydrophobicContact CG2-CG 4.31Å; V97-W282 HydrophobicContact CG2-CD2 3.45Å; V97-W282 VanDerWaalsContact CG2-CD2 3.45Å; V97-W282 HydrophobicContact CG2-CE3 3.38Å; V97-W282 HydrophobicContact CG2-CG 4.14Å; V97-W282 HydrophobicContact CG2-CH2 3.84Å; V97-W282 HydrophobicContact CG2-CZ2 3.91Å; V97-W282 HydrophobicContact CG2-CZ3 3.57Å; L100-W282 WeakPolarHBondContact CD1-O 3.27Å; L100-W282 WeakPolarHBondContact CD2-O 3.3Å; G278-W282 WeakPolarHBondContact O-CB 3.01Å; G278-W282 VanDerWaalsContact O-CD1 3.27Å; G278-W282 PolarHBondContact O-N 2.68Å; W280-W282 PolarHBondContact O-N 3.41Å; W282-I288 HydrophobicContact CE3-CG2 3.66Å; W282-I288 HydrophobicContact CZ3-CD1 4.46Å; W282-I288 HydrophobicContact CZ3-CG2 4.16Å; W282-I288 WeakPolarHBondContact O-CG2 3.13Å; W282-K312 VanDerWaalsContact CH2-CE 3.49Å
283	C	94.3	Very high	93.2	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.051	C	C	.	.	I	π-helix	trans	-98.7	-18.7	-169.1	-53.7	0	0	0	0	114.4	F104 Y108 I279 V289	F104-C283 HydrophobicContact CB-CB 4.29Å; F104-C283 HydrophobicContact CD1-CB 3.92Å; F104-C283 HydrophobicContact CD2-CB 3.54Å; F104-C283 WeakPolarHBondContact CD2-SG 3.25Å; F104-C283 HydrophobicContact CE1-CB 4.03Å; F104-C283 HydrophobicContact CE2-CB 3.67Å; F104-C283 VanDerWaalsContact CE2-SG 3.58Å; F104-C283 HydrophobicContact CG-CB 3.65Å; F104-C283 HydrophobicContact CZ-CB 3.91Å; Y108-C283 WeakPolarHBondContact CE2-O 3.31Å; Y108-C283 PolarHBondContact OH-O 3.36Å; I279-C283 HydrophobicContact CG2-CB 4.48Å; I279-C283 WeakPolarHBondContact O-CA 3.18Å; I279-C283 WeakPolarHBondContact O-CB 3.35Å; I279-C283 PolarHBondContact O-N 2.86Å; C283-V289 WeakPolarHBondContact O-CG2 3.44Å
284	S	92.9	Very high	93	Very high	9 Å²	9	8.7 Å²	8.7	6%	0.063	5%	0.051	C	C	.	.	I	π-helix	trans	-123.6	-16.4	-174.6	-55.9	0	0	0	0	114.2	M116 I279 W280 F462	M116-S284 VanDerWaalsContact CG-O 3.31Å; M116-S284 WeakPolarHBondContact CG-O 3.37Å; I279-S284 PolarHBondContact O-N 3.01Å; W280-S284 CarbonylContact O-C 3.59Å; W280-S284 WeakPolarHBondContact O-CA 3.41Å; W280-S284 WeakPolarHBondContact O-CB 3.29Å; W280-S284 PolarHBondContact O-N 2.74Å; S284-F462 WeakPolarHBondContact OG-CB 3.29Å; S284-F462 WeakPolarHBondContact OG-CG 3.5Å
285	D	93.8	Very high	92.9	Very high	6 Å²	6	8.7 Å²	8.7	3%	0.032	5%	0.052	C	C	.	.			trans	-72.1	130.5	178.8	-165.8	-43.7	0	0	0	111.8	Y141 K145 W280 Y281 V287 I288 V289	Y141-D285 PolarHBondContact OH-OD1 3.18Å; K145-D285 WeakPolarHBondContact CE-OD2 3.43Å; K145-D285 VanDerWaalsContact NZ-CG 3.29Å; K145-D285 IonicContact NZ-OD1 2.84Å; K145-D285 PolarHBondContact NZ-OD1 3.41Å; K145-D285 IonicContact NZ-OD2 3.57Å; K145-D285 PolarHBondContact NZ-OD2 3.14Å; W280-D285 PolarHBondContact O-N 3.45Å; Y281-D285 WeakPolarHBondContact O-CB 3.26Å; D285-V287 VanDerWaalsContact C-N 3.3Å; D285-V287 PolarHBondContact O-N 3.01Å; D285-V287 WeakPolarHBondContact OD1-CB 3.35Å; D285-V287 PolarHBondContact OD1-N 3.47Å; D285-I288 HydrophobicContact CB-CG1 4.38Å; D285-I288 PolarHBondContact O-N 3.06Å; D285-V289 WeakPolarHBondContact O-CG2 3.48Å; D285-V289 PolarHBondContact O-N 3.3Å
286	Q	92.8	Very high	92.6	Very high	4 Å²	4	14.2 Å²	14.2	2%	0.019	7%	0.068	C	C	.	.	H	α-helix	trans	-62.2	-37.5	-179.5	-174.8	67.6	23.2	0	0	111.7	I114 T115 Y141 I288 Q290 L395	I114-Q286 PolarHBondContact O-NE2 2.63Å; T115-Q286 VanDerWaalsContact CA-OE1 3.27Å; Y141-Q286 VanDerWaalsContact OH-CB 3.31Å; Y141-Q286 WeakPolarHBondContact OH-CB 3.38Å; Y141-Q286 PolarHBondContact OH-N 3.46Å; Q286-I288 VanDerWaalsContact C-N 3.28Å; Q286-I288 PolarHBondContact O-N 2.53Å; Q286-Q290 WeakPolarHBondContact O-CB 3.42Å; Q286-Q290 PolarHBondContact O-N 2.56Å; Q286-L395 HydrophobicContact CB-CD1 4.17Å; Q286-L395 HydrophobicContact CB-CD2 4.38Å; Q286-L395 HydrophobicContact CB-CG 4.33Å; Q286-L395 HydrophobicContact CG-CD1 4.46Å; Q286-L395 HydrophobicContact CG-CD2 4.24Å; Q286-L395 HydrophobicContact CG-CG 4.12Å
287	V	92	Very high	92.2	Very high	2 Å²	2	15.9 Å²	15.9	1%	0.012	8%	0.08	C	C	.	.	H	α-helix	trans	-59.8	-40.3	-177.4	178.9	0	0	0	0	111.7	Y141 D285 R291 S391	Y141-V287 HydrophobicContact CE1-CG2 4.36Å; Y141-V287 HydrophobicContact CE2-CG2 4.36Å; D285-V287 VanDerWaalsContact C-N 3.3Å; D285-V287 PolarHBondContact O-N 3.01Å; D285-V287 WeakPolarHBondContact OD1-CB 3.35Å; D285-V287 PolarHBondContact OD1-N 3.47Å; V287-R291 PolarHBondContact O-NH1 2.94Å; V287-S391 WeakPolarHBondContact CA-OG 3.13Å
288	I	94.1	Very high	91.9	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-83.7	-51.2	-175.9	-58.4	-54.9	0	0	0	110.5	L62 L100 Y281 W282 D285 Q286 Q290 R291	L62-I288 HydrophobicContact CD2-CG2 3.62Å; L62-I288 WeakPolarHBondContact CD2-O 3.28Å; L100-I288 HydrophobicContact CD2-CG2 3.92Å; Y281-I288 HydrophobicContact CD1-CG1 4.36Å; Y281-I288 HydrophobicContact CE1-CD1 3.97Å; Y281-I288 HydrophobicContact CE1-CG1 3.91Å; Y281-I288 WeakPolarHBondContact O-CG1 3.42Å; W282-I288 HydrophobicContact CE3-CG2 3.66Å; W282-I288 HydrophobicContact CZ3-CD1 4.46Å; W282-I288 HydrophobicContact CZ3-CG2 4.16Å; W282-I288 WeakPolarHBondContact O-CG2 3.13Å; D285-I288 HydrophobicContact CB-CG1 4.38Å; D285-I288 PolarHBondContact O-N 3.06Å; Q286-I288 VanDerWaalsContact C-N 3.28Å; Q286-I288 PolarHBondContact O-N 2.53Å; I288-Q290 VanDerWaalsContact C-N 3.3Å; I288-Q290 PolarHBondContact O-N 3.47Å; I288-R291 PolarHBondContact O-N 3.23Å
289	V	93.8	Very high	91.7	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-65.6	-35.8	-175.4	-178.1	0	0	0	0	111.4	L100 Y108 M116 C283 D285 R291 C292 L293	L100-V289 HydrophobicContact CD1-CG2 4.12Å; Y108-V289 HydrophobicContact CD2-CG1 3.49Å; Y108-V289 VanDerWaalsContact CD2-CG1 3.49Å; Y108-V289 HydrophobicContact CE2-CG1 3.76Å; Y108-V289 HydrophobicContact CE2-CG2 4.13Å; M116-V289 HydrophobicContact CE-CB 3.83Å; M116-V289 HydrophobicContact CE-CG1 3.26Å; M116-V289 HydrophobicContact CG-CB 4.42Å; M116-V289 HydrophobicContact SD-CB 3.87Å; M116-V289 HydrophobicContact SD-CG1 3.58Å; M116-V289 VanDerWaalsContact SD-CG1 3.58Å; M116-V289 HydrophobicContact SD-CG2 4.01Å; C283-V289 WeakPolarHBondContact O-CG2 3.44Å; D285-V289 WeakPolarHBondContact O-CG2 3.48Å; D285-V289 PolarHBondContact O-N 3.3Å; V289-R291 PolarHBondContact O-N 3.22Å; V289-C292 WeakPolarHBondContact O-CB 3.31Å; V289-C292 PolarHBondContact O-N 3.46Å; V289-C292 VanDerWaalsContact O-N 3.08Å; V289-L293 HydrophobicContact CG1-CD1 4.16Å; V289-L293 HydrophobicContact CG1-CG 4.16Å; V289-L293 WeakPolarHBondContact O-CG 3.36Å; V289-L293 PolarHBondContact O-N 2.94Å
290	Q	90.8	Very high	91.6	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-58.3	-32.5	179.1	-174.7	170	1.2	0	0	112.9	F47 L48 L185 Q286 I288 L293 A294 N390 S391 T394	F47-Q290 PolarHBondContact O-NE2 3.38Å; L48-Q290 HydrophobicContact CD2-CG 4.49Å; L185-Q290 HydrophobicContact CD2-CG 3.98Å; Q286-Q290 WeakPolarHBondContact O-CB 3.42Å; Q286-Q290 PolarHBondContact O-N 2.56Å; I288-Q290 VanDerWaalsContact C-N 3.3Å; I288-Q290 PolarHBondContact O-N 3.47Å; Q290-L293 PolarHBondContact O-N 3.06Å; Q290-A294 PolarHBondContact O-N 3.16Å; Q290-N390 PolarHBondContact NE2-ND2 2.87Å; Q290-S391 PolarHBondContact OE1-OG 3.14Å; Q290-T394 PolarHBondContact NE2-OG1 3.48Å
291	R	91.8	Very high	91.6	Very high	1 Å²	1	21.2 Å²	21.2	0%	0.004	11%	0.106	C	C	.	.	H	α-helix	trans	-72.7	-38	176.4	-70.1	173.4	156.3	82.4	-3	113	S61 L62 S65 M189 D192 V287 I288 V289 L293 A294 S387	S61-R291 WeakPolarHBondContact OG-CD 3.32Å; S61-R291 PolarHBondContact OG-NE 3.01Å; L62-R291 HydrophobicContact CD2-CB 4.12Å; S65-R291 VanDerWaalsContact OG-CD 3.32Å; S65-R291 WeakPolarHBondContact OG-CD 3.43Å; S65-R291 PolarHBondContact OG-NE 2.82Å; S65-R291 PolarHBondContact OG-NH1 3.32Å; S65-R291 PolarHBondContact OG-NH2 3.44Å; S65-R291 VanDerWaalsContact OG-NH2 3.16Å; M189-R291 HydrophobicContact CE-CB 4.46Å; D192-R291 IonicContact OD2-CZ 3.8Å; D192-R291 IonicContact OD2-NE 3.69Å; D192-R291 IonicContact OD2-NH2 3.75Å; D192-R291 PolarHBondContact OD2-NH2 3.04Å; V287-R291 PolarHBondContact O-NH1 2.94Å; I288-R291 PolarHBondContact O-N 3.23Å; V289-R291 PolarHBondContact O-N 3.22Å; R291-L293 VanDerWaalsContact C-N 3.29Å; R291-L293 PolarHBondContact O-N 2.93Å; R291-A294 PolarHBondContact O-N 3.19Å; R291-S387 PolarHBondContact NH2-OG 3.31Å
292	C	92.3	Very high	91.5	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-62.6	-39.9	171.5	-71.7	0	0	0	0	111.1	V105 V289 A294 A295 V301	V105-C292 HydrophobicContact CG1-CB 4.27Å; V105-C292 HydrophobicContact CG2-CB 3.63Å; V289-C292 WeakPolarHBondContact O-CB 3.31Å; V289-C292 PolarHBondContact O-N 3.46Å; V289-C292 VanDerWaalsContact O-N 3.08Å; C292-A294 PolarHBondContact O-N 2.7Å; C292-A295 WeakPolarHBondContact O-CB 3.27Å; C292-A295 PolarHBondContact O-N 3.18Å; C292-V301 HydrophobicContact CB-CG1 4.03Å; C292-V301 WeakPolarHBondContact O-CG2 3.45Å
293	L	89.3	Confident	91.5	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-69.9	-17.4	178.4	-63.9	177.3	0	0	0	113.8	L48 L109 M116 V289 Q290 R291 A295	L48-L293 HydrophobicContact CD2-CB 4.09Å; L109-L293 HydrophobicContact CD2-CD2 3.57Å; L109-L293 HydrophobicContact CG-CD2 3.87Å; M116-L293 HydrophobicContact CE-CD1 3.91Å; V289-L293 HydrophobicContact CG1-CD1 4.16Å; V289-L293 HydrophobicContact CG1-CG 4.16Å; V289-L293 WeakPolarHBondContact O-CG 3.36Å; V289-L293 PolarHBondContact O-N 2.94Å; Q290-L293 PolarHBondContact O-N 3.06Å; R291-L293 VanDerWaalsContact C-N 3.29Å; R291-L293 PolarHBondContact O-N 2.93Å; L293-A295 VanDerWaalsContact C-N 3.32Å
294	A	88.6	Confident	91.6	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.12	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.1	-6.8	175.6	0	0	0	0	0	113.7	L48 A49 R51 S52 M53 L185 M189 Q290 R291 C292	L48-A294 WeakPolarHBondContact O-CB 3.39Å; A49-A294 HydrophobicContact CB-CB 4.37Å; R51-A294 CarbonylContact C-O 3.5Å; R51-A294 VanDerWaalsContact CA-O 3.25Å; R51-A294 WeakPolarHBondContact CA-O 3.42Å; S52-A294 PolarHBondContact N-O 3.06Å; M53-A294 WeakPolarHBondContact CB-O 3Å; M53-A294 HydrophobicContact CG-CB 4.23Å; M53-A294 PolarHBondContact N-O 3.45Å; L185-A294 HydrophobicContact CD2-CB 4.24Å; M189-A294 HydrophobicContact CE-CB 4.46Å; M189-A294 HydrophobicContact SD-CB 3.85Å; Q290-A294 PolarHBondContact O-N 3.16Å; R291-A294 PolarHBondContact O-N 3.19Å; C292-A294 PolarHBondContact O-N 2.7Å
295	A	89.9	Confident	91.7	Very high	7 Å²	7	22.6 Å²	22.6	6%	0.058	12%	0.117	C	C	.	.	B	Isolated β-bridge	trans	-67.4	149.1	178.2	0	0	0	0	0	112.4	V58 C292 L293 S297 H300 V301	V58-A295 HydrophobicContact CG2-CB 3.87Å; C292-A295 WeakPolarHBondContact O-CB 3.27Å; C292-A295 PolarHBondContact O-N 3.18Å; L293-A295 VanDerWaalsContact C-N 3.32Å; A295-S297 VanDerWaalsContact C-N 3.33Å; A295-S297 PolarHBondContact O-N 2.9Å; A295-H300 HydrophobicContact CB-CB 4.23Å; A295-V301 HydrophobicContact CB-CG2 3.45Å; A295-V301 VanDerWaalsContact CB-CG2 3.45Å
296	R	87.8	Confident	91.8	Very high	158 Å²	158	25.5 Å²	25.5	60%	0.596	13%	0.132	S	C	*	.	S	Bend	trans	-70.1	-23.6	179.1	70.5	-179	-171.3	178.6	1.3	115.5	R51 M53 H300	R51-R296 VanDerWaalsContact O-CA 3.24Å; R51-R296 WeakPolarHBondContact O-CA 3.38Å; M53-R296 PolarHBondContact O-N 2.91Å; R296-H300 HydrophobicContact CG-CB 4.23Å; R296-H300 PolarHBondContact NE-CD2 3.37Å; R296-H300 PolarHBondContact NE-CE1 2.93Å; R296-H300 PolarHBondContact NE-ND1 3.31Å; R296-H300 PolarHBondContact NE-NE2 3.27Å; R296-H300 PolarHBondContact NH2-CE1 3.42Å; R296-H300 PolarHBondContact NH2-NE2 2.99Å
297	S	87.6	Confident	92	Very high	48 Å²	48	27.1 Å²	27.1	34%	0.336	14%	0.142	S	C	.	.	S	Bend	trans	-160.2	164	178.9	66.6	0	0	0	0	111.6	A295 T299 H300 V301	A295-S297 VanDerWaalsContact C-N 3.33Å; A295-S297 PolarHBondContact O-N 2.9Å; S297-T299 VanDerWaalsContact C-N 3.27Å; S297-T299 PolarHBondContact O-N 3.09Å; S297-H300 WeakPolarHBondContact O-CA 3.33Å; S297-H300 WeakPolarHBondContact O-CB 3.22Å; S297-H300 PolarHBondContact O-N 3.46Å; S297-H300 PolarHBondContact OG-CD2 3.08Å; S297-V301 PolarHBondContact O-N 3.16Å; S297-V301 VanDerWaalsContact O-N 3.12Å
298	L	86.7	Confident	92.2	Very high	61 Å²	61	27 Å²	27	32%	0.319	14%	0.141	S	C	.	.	H	α-helix	trans	-62.5	-34.3	179.5	-175.5	63.1	0	0	0	112.5	V105 P106 L109 H300 V301 K302	V105-L298 HydrophobicContact CG1-CD1 4.45Å; P106-L298 HydrophobicContact CB-CD1 4.38Å; P106-L298 HydrophobicContact CB-CD2 4.34Å; P106-L298 HydrophobicContact CG-CD1 3.85Å; P106-L298 HydrophobicContact CG-CD2 4.21Å; L109-L298 HydrophobicContact CD1-CD1 4.12Å; L298-H300 PolarHBondContact O-N 2.87Å; L298-V301 HydrophobicContact CD1-CB 4.45Å; L298-V301 WeakPolarHBondContact O-CB 3.48Å; L298-V301 PolarHBondContact O-N 2.76Å; L298-K302 WeakPolarHBondContact O-CG 3.46Å; L298-K302 PolarHBondContact O-N 2.64Å
299	T	90	Very high	92.2	Very high	87 Å²	87	27 Å²	27	53%	0.534	14%	0.141	S	C	.	.	H	α-helix	trans	-59.9	-38.4	172.9	-51.8	0	0	0	0	111.4	S297 K302 A303	S297-T299 VanDerWaalsContact C-N 3.27Å; S297-T299 PolarHBondContact O-N 3.09Å; T299-K302 PolarHBondContact O-N 3.33Å; T299-A303 VanDerWaalsContact O-CB 3.32Å; T299-A303 WeakPolarHBondContact O-CB 3.41Å; T299-A303 PolarHBondContact O-N 2.73Å
300	H	92.7	Very high	92.3	Very high	17 Å²	17	34.8 Å²	34.8	8%	0.079	17%	0.172	C	C	.	.	H	α-helix	trans	-69.2	-36.1	177	-83.4	-104.8	0	0	0	113	A54 W55 A295 R296 S297 L298 G304	A54-H300 WeakPolarHBondContact CA-ND1 3.25Å; W55-H300 HydrophobicContact CB-CB 4.31Å; W55-H300 WeakPolarHBondContact CB-O 3.39Å; W55-H300 AromaticContact CD1-CE1 3.45Å; W55-H300 VanDerWaalsContact CD1-CE1 3.45Å; W55-H300 AromaticContact CD1-ND1 3.76Å; W55-H300 PolarHBondContact N-ND1 3.25Å; A295-H300 HydrophobicContact CB-CB 4.23Å; R296-H300 HydrophobicContact CG-CB 4.23Å; R296-H300 PolarHBondContact NE-CD2 3.37Å; R296-H300 PolarHBondContact NE-CE1 2.93Å; R296-H300 PolarHBondContact NE-ND1 3.31Å; R296-H300 PolarHBondContact NE-NE2 3.27Å; R296-H300 PolarHBondContact NH2-CE1 3.42Å; R296-H300 PolarHBondContact NH2-NE2 2.99Å; S297-H300 WeakPolarHBondContact O-CA 3.33Å; S297-H300 WeakPolarHBondContact O-CB 3.22Å; S297-H300 PolarHBondContact O-N 3.46Å; S297-H300 PolarHBondContact OG-CD2 3.08Å; L298-H300 PolarHBondContact O-N 2.87Å; H300-G304 PolarHBondContact O-N 2.81Å
301	V	92.5	Very high	92.5	Very high	1 Å²	1	36.2 Å²	36.2	1%	0.006	18%	0.179	C	C	.	.	H	α-helix	trans	-61.4	-53.3	171.5	-178.9	0	0	0	0	110.3	V105 L109 C292 A295 S297 L298 A303 G304 C305	V105-V301 HydrophobicContact CB-CG1 3.87Å; V105-V301 HydrophobicContact CG1-CB 4.27Å; V105-V301 HydrophobicContact CG1-CG1 3.55Å; V105-V301 HydrophobicContact CG1-CG2 3.98Å; V105-V301 HydrophobicContact CG2-CG1 3.87Å; L109-V301 HydrophobicContact CD1-CG2 4.44Å; C292-V301 HydrophobicContact CB-CG1 4.03Å; C292-V301 WeakPolarHBondContact O-CG2 3.45Å; A295-V301 HydrophobicContact CB-CG2 3.45Å; A295-V301 VanDerWaalsContact CB-CG2 3.45Å; S297-V301 PolarHBondContact O-N 3.16Å; S297-V301 VanDerWaalsContact O-N 3.12Å; L298-V301 HydrophobicContact CD1-CB 4.45Å; L298-V301 WeakPolarHBondContact O-CB 3.48Å; L298-V301 PolarHBondContact O-N 2.76Å; V301-A303 PolarHBondContact O-N 3.4Å; V301-G304 PolarHBondContact O-N 2.79Å; V301-G304 VanDerWaalsContact O-N 3.12Å; V301-C305 PolarHBondContact O-N 3.27Å; V301-C305 PolarHBondContact O-SG 3.48Å
302	K	93.1	Very high	92.6	Very high	56 Å²	56	36.2 Å²	36.2	24%	0.243	18%	0.179	C	C	.	.	H	α-helix	trans	-58.3	-46.6	-178.3	-73.7	178.6	178	178.8	0	111.7	W102 L298 T299 C305 I306	W102-K302 HydrophobicContact CD2-CD 4.27Å; W102-K302 HydrophobicContact CD2-CG 4.13Å; W102-K302 HydrophobicContact CE3-CB 4.4Å; W102-K302 HydrophobicContact CE3-CG 4.07Å; W102-K302 HydrophobicContact CH2-CB 3.63Å; W102-K302 HydrophobicContact CH2-CD 4.45Å; W102-K302 HydrophobicContact CH2-CG 4.06Å; W102-K302 HydrophobicContact CZ2-CB 4.04Å; W102-K302 HydrophobicContact CZ2-CD 4.04Å; W102-K302 HydrophobicContact CZ2-CG 4.14Å; W102-K302 HydrophobicContact CZ3-CB 3.85Å; W102-K302 HydrophobicContact CZ3-CG 4.04Å; L298-K302 WeakPolarHBondContact O-CG 3.46Å; L298-K302 PolarHBondContact O-N 2.64Å; T299-K302 PolarHBondContact O-N 3.33Å; K302-C305 PolarHBondContact O-N 2.91Å; K302-I306 WeakPolarHBondContact O-CG1 3.35Å; K302-I306 PolarHBondContact O-N 3.25Å
303	A	95.2	Very high	92.8	Very high	27 Å²	27	39 Å²	39	22%	0.223	19%	0.194	C	C	.	.	H	α-helix	trans	-63.5	-40.9	175.4	0	0	0	0	0	112.2	W55 T299 V301 C305 I306 V307	W55-A303 HydrophobicContact CB-CB 3.62Å; W55-A303 HydrophobicContact CD2-CB 4.49Å; W55-A303 HydrophobicContact CG-CB 4.05Å; T299-A303 VanDerWaalsContact O-CB 3.32Å; T299-A303 WeakPolarHBondContact O-CB 3.41Å; T299-A303 PolarHBondContact O-N 2.73Å; V301-A303 PolarHBondContact O-N 3.4Å; A303-C305 PolarHBondContact O-N 2.96Å; A303-I306 PolarHBondContact O-N 2.8Å; A303-V307 WeakPolarHBondContact O-CG2 3.43Å; A303-V307 PolarHBondContact O-N 3.2Å
304	G	95.6	Very high	93.1	Very high	0 Å²	0	41 Å²	41	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-62.6	-40.5	174.7	0	0	0	0	0	113	W55 G59 H300 V301 V307 C308	W55-G304 VanDerWaalsContact O-CA 3.25Å; W55-G304 WeakPolarHBondContact O-CA 3.11Å; G59-G304 WeakPolarHBondContact CA-O 3.08Å; H300-G304 PolarHBondContact O-N 2.81Å; V301-G304 PolarHBondContact O-N 2.79Å; V301-G304 VanDerWaalsContact O-N 3.12Å; G304-V307 PolarHBondContact O-N 2.87Å; G304-C308 WeakPolarHBondContact O-CB 3.41Å; G304-C308 PolarHBondContact O-N 3.11Å
305	C	95.9	Very high	93.4	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-64.1	-40.8	174.7	-65.9	0	0	0	0	111.7	V97 G101 V301 K302 A303 C308 G309	V97-C305 HydrophobicContact CG1-CB 3.89Å; V97-C305 VanDerWaalsContact CG1-O 3.23Å; V97-C305 WeakPolarHBondContact CG1-O 3.47Å; G101-C305 VanDerWaalsContact CA-SG 3.58Å; V301-C305 PolarHBondContact O-N 3.27Å; V301-C305 PolarHBondContact O-SG 3.48Å; K302-C305 PolarHBondContact O-N 2.91Å; A303-C305 PolarHBondContact O-N 2.96Å; C305-C308 PolarHBondContact O-N 2.97Å; C305-G309 PolarHBondContact O-N 3.06Å
306	I	96.5	Very high	93.6	Very high	66 Å²	66	41 Å²	41	34%	0.338	20%	0.203	S	C	.	.	H	α-helix	trans	-59.9	-49	173.9	-71.2	165.8	0	0	0	110.8	L98 W102 K302 A303 C308 G309 Y310	L98-I306 HydrophobicContact CD2-CG1 3.94Å; W102-I306 HydrophobicContact CH2-CD1 3.59Å; W102-I306 HydrophobicContact CH2-CG1 3.73Å; W102-I306 HydrophobicContact CZ2-CD1 4.43Å; W102-I306 HydrophobicContact CZ3-CD1 4.46Å; W102-I306 HydrophobicContact CZ3-CG1 4.12Å; K302-I306 WeakPolarHBondContact O-CG1 3.35Å; K302-I306 PolarHBondContact O-N 3.25Å; A303-I306 PolarHBondContact O-N 2.8Å; I306-C308 PolarHBondContact O-N 2.7Å; I306-G309 PolarHBondContact O-N 2.93Å; I306-Y310 HydrophobicContact CG2-CD2 3.62Å; I306-Y310 HydrophobicContact CG2-CE2 3.43Å; I306-Y310 VanDerWaalsContact CG2-CE2 3.43Å; I306-Y310 VanDerWaalsContact O-CD2 3.29Å; I306-Y310 WeakPolarHBondContact O-CD2 3.49Å; I306-Y310 PolarHBondContact O-N 3.2Å
307	V	95.8	Very high	94	Very high	38 Å²	38	37.8 Å²	37.8	23%	0.23	19%	0.194	C	C	.	.	H	α-helix	trans	-59.5	-48.9	179.3	170.9	0	0	0	0	110.9	W55 A303 G304 G309 Y310 L311	W55-V307 HydrophobicContact CE3-CG2 3.62Å; W55-V307 HydrophobicContact CZ3-CG2 3.5Å; A303-V307 WeakPolarHBondContact O-CG2 3.43Å; A303-V307 PolarHBondContact O-N 3.2Å; G304-V307 PolarHBondContact O-N 2.87Å; V307-G309 VanDerWaalsContact C-N 3.29Å; V307-G309 PolarHBondContact O-N 3.46Å; V307-Y310 PolarHBondContact O-N 3.48Å; V307-L311 HydrophobicContact CG1-CD1 4.08Å; V307-L311 HydrophobicContact CG1-CG 4.38Å; V307-L311 WeakPolarHBondContact O-CG 3.34Å; V307-L311 PolarHBondContact O-N 2.72Å
308	C	96	Very high	94.4	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-57.6	-44.5	176.8	-179.1	0	0	0	0	111.1	L62 V97 G304 C305 I306 Y310 L311 K312	L62-C308 HydrophobicContact CB-CB 4Å; L62-C308 HydrophobicContact CD1-CB 4.28Å; V97-C308 HydrophobicContact CG1-CB 4.04Å; G304-C308 WeakPolarHBondContact O-CB 3.41Å; G304-C308 PolarHBondContact O-N 3.11Å; C305-C308 PolarHBondContact O-N 2.97Å; I306-C308 PolarHBondContact O-N 2.7Å; C308-Y310 PolarHBondContact O-N 2.77Å; C308-L311 PolarHBondContact O-N 2.7Å; C308-K312 WeakPolarHBondContact O-CG 3.2Å; C308-K312 PolarHBondContact O-N 2.71Å
309	G	95.4	Very high	94.8	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-55.5	-48.5	174.9	0	0	0	0	0	113.2	L94 C305 I306 V307 L311 K312	L94-G309 VanDerWaalsContact CD1-C 3.42Å; L94-G309 VanDerWaalsContact CD1-CA 3.43Å; L94-G309 WeakPolarHBondContact CD1-O 3.2Å; C305-G309 PolarHBondContact O-N 3.06Å; I306-G309 PolarHBondContact O-N 2.93Å; V307-G309 VanDerWaalsContact C-N 3.29Å; V307-G309 PolarHBondContact O-N 3.46Å; G309-L311 PolarHBondContact O-N 3.48Å; G309-K312 WeakPolarHBondContact O-CB 3.43Å; G309-K312 PolarHBondContact O-N 3.37Å
310	Y	94.9	Very high	95.1	Very high	163 Å²	163	29 Å²	29	64%	0.639	14%	0.14	S	C	*	.	H	α-helix	trans	-63.5	-42.1	176.4	-79.5	-65	0	0	0	112.6	I306 V307 C308 K312 L313	I306-Y310 HydrophobicContact CG2-CD2 3.62Å; I306-Y310 HydrophobicContact CG2-CE2 3.43Å; I306-Y310 VanDerWaalsContact CG2-CE2 3.43Å; I306-Y310 VanDerWaalsContact O-CD2 3.29Å; I306-Y310 WeakPolarHBondContact O-CD2 3.49Å; I306-Y310 PolarHBondContact O-N 3.2Å; V307-Y310 PolarHBondContact O-N 3.48Å; C308-Y310 PolarHBondContact O-N 2.77Å; Y310-K312 PolarHBondContact O-N 3.48Å; Y310-L313 HydrophobicContact CD1-CD1 4.4Å; Y310-L313 WeakPolarHBondContact O-CB 3.49Å; Y310-L313 PolarHBondContact O-N 3.08Å; Y310-L313 VanDerWaalsContact O-N 3.15Å
311	L	94.9	Very high	95.3	Very high	30 Å²	30	29.1 Å²	29.1	16%	0.157	14%	0.14	C	C	.	.	H	α-helix	trans	-61.2	-31.4	176.7	-67.8	179.9	0	0	0	111.9	F63 T196 I200 V307 C308 G309 L313 L314 P315	F63-L311 HydrophobicContact CB-CB 4.38Å; F63-L311 HydrophobicContact CB-CD1 3.88Å; F63-L311 HydrophobicContact CD1-CD1 4.27Å; F63-L311 HydrophobicContact CD2-CB 3.41Å; F63-L311 VanDerWaalsContact CD2-CB 3.41Å; F63-L311 HydrophobicContact CD2-CD1 4.28Å; F63-L311 HydrophobicContact CD2-CG 4.48Å; F63-L311 HydrophobicContact CE2-CB 3.71Å; F63-L311 WeakPolarHBondContact CE2-O 3.39Å; F63-L311 HydrophobicContact CG-CB 3.92Å; F63-L311 HydrophobicContact CG-CD1 3.9Å; F63-L311 HydrophobicContact CZ-CB 4.45Å; T196-L311 HydrophobicContact CG2-CD1 4.15Å; I200-L311 HydrophobicContact CD1-CD1 4.4Å; I200-L311 HydrophobicContact CD1-CD2 3.59Å; V307-L311 HydrophobicContact CG1-CD1 4.08Å; V307-L311 HydrophobicContact CG1-CG 4.38Å; V307-L311 WeakPolarHBondContact O-CG 3.34Å; V307-L311 PolarHBondContact O-N 2.72Å; C308-L311 PolarHBondContact O-N 2.7Å; G309-L311 PolarHBondContact O-N 3.48Å; L311-L313 PolarHBondContact O-N 3.33Å; L311-L314 HydrophobicContact CD2-CD1 4.05Å; L311-L314 WeakPolarHBondContact O-CB 3.48Å; L311-L314 PolarHBondContact O-N 3.34Å; L311-L314 VanDerWaalsContact O-N 3.12Å; L311-P315 WeakPolarHBondContact O-CD 3.15Å
312	K	94.4	Very high	95.6	Very high	1 Å²	1	29 Å²	29	0%	0.004	14%	0.14	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.9	-11.5	176.9	-77.7	-57.6	-145.3	154.2	0	115.6	F63 N66 E90 W282 C308 G309 Y310 L314 P315	F63-K312 HydrophobicContact CD2-CD 4.29Å; N66-K312 WeakPolarHBondContact OD1-CE 3.48Å; N66-K312 PolarHBondContact OD1-NZ 3.33Å; E90-K312 IonicContact OE1-NZ 3.9Å; E90-K312 PolarHBondContact OE1-NZ 3.33Å; E90-K312 WeakPolarHBondContact OE2-CD 3.31Å; E90-K312 IonicContact OE2-NZ 2.92Å; E90-K312 PolarHBondContact OE2-NZ 3.28Å; W282-K312 VanDerWaalsContact CH2-CE 3.49Å; C308-K312 WeakPolarHBondContact O-CG 3.2Å; C308-K312 PolarHBondContact O-N 2.71Å; G309-K312 WeakPolarHBondContact O-CB 3.43Å; G309-K312 PolarHBondContact O-N 3.37Å; Y310-K312 PolarHBondContact O-N 3.48Å; K312-L314 VanDerWaalsContact C-N 3.31Å; K312-P315 WeakPolarHBondContact O-CD 3.39Å
313	L	94.9	Very high	95.7	Very high	60 Å²	60	26.4 Å²	26.4	31%	0.314	13%	0.128	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75	-25.1	171	-64.9	175.7	0	0	0	112.3	W91 L94 Y310 L311 F317	W91-L313 HydrophobicContact CG-CD2 4.36Å; W91-L313 PolarHBondContact NE1-O 3.49Å; L94-L313 HydrophobicContact CD2-CD2 4.01Å; Y310-L313 HydrophobicContact CD1-CD1 4.4Å; Y310-L313 WeakPolarHBondContact O-CB 3.49Å; Y310-L313 PolarHBondContact O-N 3.08Å; Y310-L313 VanDerWaalsContact O-N 3.15Å; L311-L313 PolarHBondContact O-N 3.33Å; L313-F317 WeakPolarHBondContact O-CD2 3.21Å
314	L	95.6	Very high	95.9	Very high	41 Å²	41	25.1 Å²	25.1	22%	0.215	12%	0.118	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.2	-39.4	-171.7	-60.1	177	0	0	0	115.5	I200 F204 L311 K312 M316 F317 L318	I200-L314 HydrophobicContact CD1-CD1 4.48Å; I200-L314 HydrophobicContact CG2-CD1 4.14Å; F204-L314 HydrophobicContact CE2-CD1 4.41Å; F204-L314 HydrophobicContact CZ-CD2 3.96Å; L311-L314 HydrophobicContact CD2-CD1 4.05Å; L311-L314 WeakPolarHBondContact O-CB 3.48Å; L311-L314 PolarHBondContact O-N 3.34Å; L311-L314 VanDerWaalsContact O-N 3.12Å; K312-L314 VanDerWaalsContact C-N 3.31Å; L314-M316 PolarHBondContact O-N 3.49Å; L314-M316 VanDerWaalsContact O-N 3.08Å; L314-F317 PolarHBondContact O-N 3.44Å; L314-L318 HydrophobicContact CB-CD1 3.85Å; L314-L318 HydrophobicContact CB-CG 4.23Å; L314-L318 HydrophobicContact CD1-CD1 4.38Å; L314-L318 WeakPolarHBondContact O-CG 3.41Å; L314-L318 PolarHBondContact O-N 3.41Å
315	P	95.3	Very high	96	Very high	2 Å²	2	25.1 Å²	25.1	1%	0.013	12%	0.118	C	C	.	.	H	α-helix	trans	-57.5	-27.3	-174.4	-29.5	37.4	0	0	0	115.4	F63 I67 L75 E90 L311 K312 F317 M319 V320	F63-P315 HydrophobicContact CE2-CG 4.36Å; I67-P315 HydrophobicContact CD1-CG 3.83Å; L75-P315 HydrophobicContact CD2-CB 3.99Å; E90-P315 HydrophobicContact CG-CB 3.97Å; E90-P315 HydrophobicContact CG-CG 4.47Å; L311-P315 WeakPolarHBondContact O-CD 3.15Å; K312-P315 WeakPolarHBondContact O-CD 3.39Å; P315-F317 VanDerWaalsContact C-N 3.3Å; P315-F317 PolarHBondContact O-N 3.23Å; P315-M319 HydrophobicContact CB-CG 4.47Å; P315-M319 HydrophobicContact CB-SD 4.15Å; P315-M319 WeakPolarHBondContact O-CA 3.43Å; P315-M319 VanDerWaalsContact O-CB 3.31Å; P315-M319 WeakPolarHBondContact O-CB 2.98Å; P315-M319 PolarHBondContact O-N 3.22Å; P315-V320 PolarHBondContact O-N 2.94Å; P315-V320 VanDerWaalsContact O-N 3.11Å
316	M	95.1	Very high	96	Very high	4 Å²	4	25.1 Å²	25.1	2%	0.02	12%	0.118	C	C	.	.	I	π-helix	trans	-55.3	-48.6	170.5	179.3	67.9	86.4	0	0	111.1	I84 G87 W91 L256 L314 V320 F321	I84-M316 HydrophobicContact CB-SD 4.17Å; I84-M316 WeakPolarHBondContact O-CE 3.16Å; G87-M316 VanDerWaalsContact CA-CE 3.45Å; W91-M316 HydrophobicContact CD2-CE 4.31Å; W91-M316 HydrophobicContact CE3-CE 4.44Å; W91-M316 HydrophobicContact CH2-CE 4.07Å; W91-M316 HydrophobicContact CZ2-CB 4.07Å; W91-M316 HydrophobicContact CZ2-CE 3.92Å; W91-M316 HydrophobicContact CZ2-CG 3.82Å; W91-M316 HydrophobicContact CZ3-CE 4.33Å; L256-M316 HydrophobicContact CD1-CE 3.84Å; L314-M316 PolarHBondContact O-N 3.49Å; L314-M316 VanDerWaalsContact O-N 3.08Å; M316-V320 WeakPolarHBondContact O-CB 3.02Å; M316-V320 PolarHBondContact O-N 3.3Å; M316-V320 HydrophobicContact SD-CB 4.18Å; M316-V320 HydrophobicContact SD-CG1 4.2Å; M316-V320 HydrophobicContact SD-CG2 4.38Å; M316-F321 PolarHBondContact O-N 3Å; M316-F321 VanDerWaalsContact O-N 3.14Å
317	F	96	Very high	96	Very high	92 Å²	92	22.7 Å²	22.7	40%	0.404	10%	0.104	S	C	.	.	I	π-helix	trans	-82.3	-33.8	-176.8	-53.9	-74.4	0	0	0	112.3	W91 T207 L313 L314 P315 F321 P322	W91-F317 HydrophobicContact CZ2-CE2 4.39Å; W91-F317 HydrophobicContact CZ2-CZ 4.23Å; T207-F317 WeakPolarHBondContact CG2-O 3.11Å; L313-F317 WeakPolarHBondContact O-CD2 3.21Å; L314-F317 PolarHBondContact O-N 3.44Å; P315-F317 VanDerWaalsContact C-N 3.3Å; P315-F317 PolarHBondContact O-N 3.23Å; F317-F321 HydrophobicContact CD1-CD2 4.05Å; F317-F321 AromaticContact CD1-CE2 3.6Å; F317-F321 HydrophobicContact CD1-CE2 3.6Å; F317-F321 HydrophobicContact CD1-CZ 4.33Å; F317-F321 HydrophobicContact CE1-CE2 4.07Å; F317-F321 HydrophobicContact CE1-CZ 4.47Å; F317-P322 VanDerWaalsContact O-CD 3.29Å; F317-P322 WeakPolarHBondContact O-CD 3.49Å
318	L	95.7	Very high	96.1	Very high	7 Å²	7	22 Å²	22	4%	0.037	10%	0.1	C	C	.	.	I	π-helix	trans	-97	-9.5	-170.9	-59.3	-170.7	0	0	0	114.5	A203 F204 L314 Y357	A203-L318 HydrophobicContact CB-CB 3.98Å; A203-L318 HydrophobicContact CB-CD1 4.17Å; F204-L318 HydrophobicContact CD1-CD2 3.66Å; F204-L318 HydrophobicContact CD2-CD1 3.93Å; F204-L318 HydrophobicContact CD2-CD2 4.36Å; F204-L318 HydrophobicContact CE1-CD2 3.84Å; F204-L318 HydrophobicContact CE2-CD1 3.82Å; F204-L318 HydrophobicContact CG-CD1 4.31Å; F204-L318 HydrophobicContact CG-CD2 3.93Å; F204-L318 HydrophobicContact CZ-CD1 4.12Å; F204-L318 HydrophobicContact CZ-CD2 4.26Å; L314-L318 HydrophobicContact CB-CD1 3.85Å; L314-L318 HydrophobicContact CB-CG 4.23Å; L314-L318 HydrophobicContact CD1-CD1 4.38Å; L314-L318 WeakPolarHBondContact O-CG 3.41Å; L314-L318 PolarHBondContact O-N 3.41Å; L318-Y357 WeakPolarHBondContact O-CE2 2.97Å
319	M	95.1	Very high	96.1	Very high	5 Å²	5	24.4 Å²	24.4	3%	0.025	11%	0.112	C	C	.	.	I	π-helix	trans	-133.3	-50.1	179.5	-57.7	-178.2	-176.4	0	0	112.3	I67 H71 F72 L75 A76 P315 G323 Y357	I67-M319 HydrophobicContact CG2-CE 3.31Å; I67-M319 HydrophobicContact CG2-SD 4.5Å; H71-M319 HydrophobicContact CB-SD 3.9Å; F72-M319 HydrophobicContact CD1-CE 3.82Å; F72-M319 HydrophobicContact CD1-CG 4.17Å; F72-M319 HydrophobicContact CD1-SD 4.13Å; F72-M319 HydrophobicContact CD2-CE 4.21Å; F72-M319 HydrophobicContact CE1-CE 3.35Å; F72-M319 HydrophobicContact CE1-CG 4.12Å; F72-M319 HydrophobicContact CE1-SD 4.19Å; F72-M319 HydrophobicContact CE2-CE 3.78Å; F72-M319 HydrophobicContact CG-CE 4.23Å; F72-M319 HydrophobicContact CZ-CE 3.32Å; L75-M319 HydrophobicContact CD2-CB 4.37Å; L75-M319 HydrophobicContact CD2-SD 4.37Å; A76-M319 WeakPolarHBondContact CB-O 3.5Å; P315-M319 HydrophobicContact CB-CG 4.47Å; P315-M319 HydrophobicContact CB-SD 4.15Å; P315-M319 WeakPolarHBondContact O-CA 3.43Å; P315-M319 VanDerWaalsContact O-CB 3.31Å; P315-M319 WeakPolarHBondContact O-CB 2.98Å; P315-M319 PolarHBondContact O-N 3.22Å; M319-G323 PolarHBondContact O-N 3.44Å; M319-Y357 HydrophobicContact CG-CE2 4.47Å
320	V	96.9	Very high	96.1	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	12%	0.122	C	C	.	.	I	π-helix	trans	-66.9	-49.2	-177.3	179.5	0	0	0	0	111	L75 V86 P315 M316 G323 M324	L75-V320 HydrophobicContact CD1-CG2 4.41Å; L75-V320 HydrophobicContact CD2-CG2 4.07Å; L75-V320 HydrophobicContact CG-CG2 3.88Å; V86-V320 HydrophobicContact CG1-CG1 4.12Å; V86-V320 HydrophobicContact CG1-CG2 3.81Å; P315-V320 PolarHBondContact O-N 2.94Å; P315-V320 VanDerWaalsContact O-N 3.11Å; M316-V320 WeakPolarHBondContact O-CB 3.02Å; M316-V320 PolarHBondContact O-N 3.3Å; M316-V320 HydrophobicContact SD-CB 4.18Å; M316-V320 HydrophobicContact SD-CG1 4.2Å; M316-V320 HydrophobicContact SD-CG2 4.38Å; V320-G323 PolarHBondContact O-N 3.05Å; V320-G323 VanDerWaalsContact O-N 3.17Å; V320-M324 HydrophobicContact CG1-SD 4.49Å; V320-M324 WeakPolarHBondContact O-CG 3.2Å; V320-M324 PolarHBondContact O-N 3.12Å
321	F	97.4	Very high	96	Very high	18 Å²	18	20.5 Å²	20.5	8%	0.079	10%	0.1	C	C	.	.	H	α-helix	trans	-60.9	-49.1	175.8	-73.9	-5.1	0	0	0	113.2	I84 F211 Y217 L220 M316 F317 G323 M324 I325	I84-F321 HydrophobicContact CG2-CD1 4.42Å; I84-F321 HydrophobicContact CG2-CE1 3.82Å; F211-F321 HydrophobicContact CE2-CB 4.38Å; F211-F321 HydrophobicContact CE2-CD2 4.25Å; F211-F321 HydrophobicContact CZ-CB 4.1Å; F211-F321 AromaticContact CZ-CD2 3.78Å; F211-F321 HydrophobicContact CZ-CD2 3.78Å; F211-F321 HydrophobicContact CZ-CG 4.25Å; Y217-F321 HydrophobicContact CD2-CE2 4.38Å; Y217-F321 AromaticContact CE2-CE2 3.94Å; Y217-F321 HydrophobicContact CE2-CE2 3.94Å; Y217-F321 AromaticContact CE2-CZ 3.88Å; Y217-F321 HydrophobicContact CE2-CZ 3.88Å; L220-F321 HydrophobicContact CD2-CB 4.45Å; L220-F321 HydrophobicContact CD2-CD1 4.24Å; L220-F321 HydrophobicContact CD2-CG 4.19Å; M316-F321 PolarHBondContact O-N 3Å; M316-F321 VanDerWaalsContact O-N 3.14Å; F317-F321 HydrophobicContact CD1-CD2 4.05Å; F317-F321 AromaticContact CD1-CE2 3.6Å; F317-F321 HydrophobicContact CD1-CE2 3.6Å; F317-F321 HydrophobicContact CD1-CZ 4.33Å; F317-F321 HydrophobicContact CE1-CE2 4.07Å; F317-F321 HydrophobicContact CE1-CZ 4.47Å; F321-G323 VanDerWaalsContact C-N 3.28Å; F321-G323 PolarHBondContact O-N 3.19Å; F321-M324 HydrophobicContact CD1-SD 4.31Å; F321-M324 WeakPolarHBondContact O-CB 3.2Å; F321-M324 PolarHBondContact O-N 3.36Å; F321-M324 VanDerWaalsContact O-N 3.13Å; F321-I325 VanDerWaalsContact O-CG1 3.3Å; F321-I325 WeakPolarHBondContact O-CG1 3.32Å; F321-I325 PolarHBondContact O-N 3.21Å
322	P	97	Very high	95.9	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-53.3	-43.2	169.8	-31.8	37.8	0	0	0	113.1	T207 F317 M324 I325 S326 Y357 L360	T207-P322 HydrophobicContact CG2-CG 4.36Å; T207-P322 WeakPolarHBondContact OG1-CG 3.41Å; F317-P322 VanDerWaalsContact O-CD 3.29Å; F317-P322 WeakPolarHBondContact O-CD 3.49Å; P322-M324 VanDerWaalsContact C-N 3.35Å; P322-M324 PolarHBondContact O-N 2.81Å; P322-I325 PolarHBondContact O-N 3.21Å; P322-I325 VanDerWaalsContact O-N 3.16Å; P322-S326 PolarHBondContact O-N 3.26Å; P322-Y357 HydrophobicContact CB-CD2 4.14Å; P322-Y357 HydrophobicContact CB-CE2 4.06Å; P322-Y357 HydrophobicContact CG-CE2 4.48Å; P322-L360 HydrophobicContact CB-CD1 3.92Å; P322-L360 WeakPolarHBondContact O-CD1 3.41Å
323	G	96.9	Very high	95.8	Very high	0 Å²	0	25 Å²	25	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-54	-48.7	174	0	0	0	0	0	113.1	A76 A80 M319 V320 F321 I325 S326 R327	A76-G323 WeakPolarHBondContact O-CA 3.36Å; A80-G323 WeakPolarHBondContact CB-O 3.36Å; M319-G323 PolarHBondContact O-N 3.44Å; V320-G323 PolarHBondContact O-N 3.05Å; V320-G323 VanDerWaalsContact O-N 3.17Å; F321-G323 VanDerWaalsContact C-N 3.28Å; F321-G323 PolarHBondContact O-N 3.19Å; G323-I325 PolarHBondContact O-N 3.42Å; G323-S326 WeakPolarHBondContact O-CB 3.35Å; G323-S326 PolarHBondContact O-N 2.02Å; G323-R327 PolarHBondContact O-N 2.61Å
324	M	97.7	Very high	95.7	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-62.3	-41.6	175.9	-65.1	177.9	76.2	0	0	112.7	G79 I84 L220 Y224 F254 V320 F321 P322 S326 R327 I328	G79-M324 WeakPolarHBondContact O-CG 3.34Å; I84-M324 HydrophobicContact CG2-CE 4.28Å; I84-M324 HydrophobicContact CG2-SD 3.66Å; L220-M324 HydrophobicContact CD1-CB 3.9Å; Y224-M324 HydrophobicContact CD1-CE 3.91Å; Y224-M324 HydrophobicContact CD2-CB 3.9Å; Y224-M324 HydrophobicContact CD2-CE 3.79Å; Y224-M324 HydrophobicContact CD2-CG 4.35Å; Y224-M324 HydrophobicContact CE1-CE 3.93Å; Y224-M324 HydrophobicContact CE2-CB 3.84Å; Y224-M324 HydrophobicContact CE2-CE 3.8Å; Y224-M324 HydrophobicContact CE2-CG 3.92Å; Y224-M324 HydrophobicContact CG-CE 3.84Å; F254-M324 HydrophobicContact CD1-CE 4.13Å; F254-M324 HydrophobicContact CE1-CE 3.38Å; F254-M324 HydrophobicContact CE1-SD 4.26Å; F254-M324 HydrophobicContact CE2-CE 3.99Å; F254-M324 HydrophobicContact CZ-CE 3.3Å; V320-M324 HydrophobicContact CG1-SD 4.49Å; V320-M324 WeakPolarHBondContact O-CG 3.2Å; V320-M324 PolarHBondContact O-N 3.12Å; F321-M324 HydrophobicContact CD1-SD 4.31Å; F321-M324 WeakPolarHBondContact O-CB 3.2Å; F321-M324 PolarHBondContact O-N 3.36Å; F321-M324 VanDerWaalsContact O-N 3.13Å; P322-M324 VanDerWaalsContact C-N 3.35Å; P322-M324 PolarHBondContact O-N 2.81Å; M324-S326 VanDerWaalsContact C-N 3.31Å; M324-S326 PolarHBondContact O-N 2.69Å; M324-R327 PolarHBondContact O-N 3.33Å; M324-I328 PolarHBondContact O-N 3.28Å
325	I	98	Very high	95.4	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-63	-40	176.7	-66.6	168.2	0	0	0	110.9	F211 I214 L220 F321 P322 G323 R327 I328 L329	F211-I325 HydrophobicContact CD1-CD1 3.9Å; F211-I325 HydrophobicContact CD2-CD1 4.11Å; F211-I325 HydrophobicContact CE1-CD1 3.89Å; F211-I325 HydrophobicContact CE2-CD1 4.09Å; F211-I325 HydrophobicContact CG-CD1 4.01Å; F211-I325 HydrophobicContact CZ-CD1 3.98Å; I214-I325 HydrophobicContact CD1-CD1 4.11Å; I214-I325 HydrophobicContact CD1-CG1 3.78Å; I214-I325 HydrophobicContact CG1-CG1 4.5Å; I214-I325 HydrophobicContact CG1-CG2 4.47Å; I214-I325 HydrophobicContact CG2-CG2 3.76Å; L220-I325 HydrophobicContact CD1-CG1 3.82Å; F321-I325 VanDerWaalsContact O-CG1 3.3Å; F321-I325 WeakPolarHBondContact O-CG1 3.32Å; F321-I325 PolarHBondContact O-N 3.21Å; P322-I325 PolarHBondContact O-N 3.21Å; P322-I325 VanDerWaalsContact O-N 3.16Å; G323-I325 PolarHBondContact O-N 3.42Å; I325-R327 VanDerWaalsContact C-N 3.27Å; I325-R327 PolarHBondContact O-N 3.24Å; I325-I328 WeakPolarHBondContact O-CA 3.4Å; I325-I328 WeakPolarHBondContact O-CB 3.35Å; I325-I328 PolarHBondContact O-N 3.15Å; I325-L329 HydrophobicContact CG2-CD1 3.99Å; I325-L329 HydrophobicContact CG2-CG 4.28Å; I325-L329 PolarHBondContact O-N 2.9Å
326	S	97.3	Very high	95.1	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-58.2	-40.7	177.7	-165	0	0	0	0	112.1	P322 G323 M324 I328 L329 Y330 A356	P322-S326 PolarHBondContact O-N 3.26Å; G323-S326 WeakPolarHBondContact O-CB 3.35Å; G323-S326 PolarHBondContact O-N 2.02Å; M324-S326 VanDerWaalsContact C-N 3.31Å; M324-S326 PolarHBondContact O-N 2.69Å; S326-I328 VanDerWaalsContact C-N 3.32Å; S326-I328 PolarHBondContact O-N 2.86Å; S326-L329 PolarHBondContact O-N 2.85Å; S326-Y330 PolarHBondContact O-N 2.82Å; S326-A356 VanDerWaalsContact CB-O 3.23Å; S326-A356 WeakPolarHBondContact CB-O 3.35Å; S326-A356 VanDerWaalsContact OG-C 3.32Å; S326-A356 WeakPolarHBondContact OG-CA 3.27Å; S326-A356 PolarHBondContact OG-O 3.41Å
327	R	96.3	Very high	94.7	Very high	15 Å²	15	21.4 Å²	21.4	6%	0.057	11%	0.107	C	C	.	.	H	α-helix	trans	-63.9	-36	174.5	-175.5	174.1	178.5	160.9	4.9	112.6	A80 A81 A227 Y247 G323 M324 I325 P331 V334	A80-R327 HydrophobicContact CB-CB 4.34Å; A80-R327 WeakPolarHBondContact O-CD 3.43Å; A80-R327 PolarHBondContact O-NH1 2.88Å; A80-R327 VanDerWaalsContact O-NH1 3.08Å; A81-R327 PolarHBondContact O-NH1 3.04Å; A227-R327 HydrophobicContact CB-CG 3.98Å; A227-R327 PolarHBondContact O-NE 3.42Å; Y247-R327 PolarHBondContact O-NH2 3.14Å; G323-R327 PolarHBondContact O-N 2.61Å; M324-R327 PolarHBondContact O-N 3.33Å; I325-R327 VanDerWaalsContact C-N 3.27Å; I325-R327 PolarHBondContact O-N 3.24Å; R327-P331 WeakPolarHBondContact O-CA 3.18Å; R327-V334 HydrophobicContact CB-CG1 4.21Å
328	I	97	Very high	94.4	Very high	25 Å²	25	17.4 Å²	17.4	13%	0.128	9%	0.09	C	C	.	.	H	α-helix	trans	-65.5	-44.5	176.8	-65.7	167.7	0	0	0	110.9	I214 L220 K223 Y224 A227 M324 I325 S326	I214-I328 HydrophobicContact CG2-CB 4.44Å; I214-I328 HydrophobicContact CG2-CG2 3.97Å; L220-I328 HydrophobicContact CD1-CD1 3.59Å; K223-I328 HydrophobicContact CB-CD1 4.1Å; K223-I328 HydrophobicContact CB-CG1 4.35Å; K223-I328 HydrophobicContact CB-CG2 3.79Å; K223-I328 HydrophobicContact CD-CG2 4.21Å; Y224-I328 HydrophobicContact CD2-CG1 4.39Å; A227-I328 HydrophobicContact CB-CG1 4.15Å; M324-I328 PolarHBondContact O-N 3.28Å; I325-I328 WeakPolarHBondContact O-CA 3.4Å; I325-I328 WeakPolarHBondContact O-CB 3.35Å; I325-I328 PolarHBondContact O-N 3.15Å; S326-I328 VanDerWaalsContact C-N 3.32Å; S326-I328 PolarHBondContact O-N 2.86Å
329	L	96.1	Very high	93.9	Very high	50 Å²	50	17.2 Å²	17.2	26%	0.262	9%	0.089	S	C	.	.	H	α-helix	trans	-77.4	-33.8	-177	-65	178.7	0	0	0	112.6	E213 I214 I325 S326 P331 L360 V364	E213-L329 HydrophobicContact CB-CD1 3.99Å; E213-L329 HydrophobicContact CB-CD2 4.25Å; E213-L329 HydrophobicContact CG-CD1 4.48Å; I214-L329 HydrophobicContact CG2-CD2 3.79Å; I214-L329 HydrophobicContact CG2-CG 4.07Å; I325-L329 HydrophobicContact CG2-CD1 3.99Å; I325-L329 HydrophobicContact CG2-CG 4.28Å; I325-L329 PolarHBondContact O-N 2.9Å; S326-L329 PolarHBondContact O-N 2.85Å; L329-P331 VanDerWaalsContact C-CD 3.44Å; L329-L360 HydrophobicContact CD1-CD2 3.86Å; L329-V364 HydrophobicContact CD1-CG2 4.29Å
330	Y	95.5	Very high	93.5	Very high	52 Å²	52	20.4 Å²	20.4	20%	0.204	10%	0.104	C	C	.	.			trans	-128.8	58.3	-173.8	-51.6	-68.4	0	0	0	112.6	S326 N332 E333 V334 K359 L360 T363	S326-Y330 PolarHBondContact O-N 2.82Å; Y330-N332 VanDerWaalsContact C-N 3.3Å; Y330-N332 PolarHBondContact O-N 3.47Å; Y330-E333 PolarHBondContact O-N 2.93Å; Y330-V334 WeakPolarHBondContact O-CB 3.44Å; Y330-V334 PolarHBondContact O-N 3.14Å; Y330-K359 HydrophobicContact CD2-CG 3.6Å; Y330-K359 HydrophobicContact CE2-CG 3.91Å; Y330-K359 HydrophobicContact CG-CG 3.99Å; Y330-L360 HydrophobicContact CE2-CD2 4.19Å; Y330-T363 WeakPolarHBondContact CE2-OG1 3.46Å; Y330-T363 VanDerWaalsContact CZ-OG1 3.28Å; Y330-T363 WeakPolarHBondContact OH-CB 3.44Å; Y330-T363 PolarHBondContact OH-OG1 3.23Å
331	P	93.9	Very high	93.1	Very high	28 Å²	28	22.5 Å²	22.5	18%	0.182	12%	0.115	C	C	.	.	H	α-helix	trans	-63.8	-34	-174.4	25.3	-34.5	0	0	0	113	R327 L329 E333 G335	R327-P331 WeakPolarHBondContact O-CA 3.18Å; L329-P331 VanDerWaalsContact C-CD 3.44Å; P331-E333 VanDerWaalsContact C-N 3.31Å; P331-E333 PolarHBondContact O-N 3.41Å; P331-G335 CarbonylContact O-C 3.05Å; P331-G335 VanDerWaalsContact O-C 3.3Å; P331-G335 WeakPolarHBondContact O-CA 3.39Å; P331-G335 PolarHBondContact O-N 3.45Å
332	N	92.4	Very high	92.6	Very high	71 Å²	71	21.7 Å²	21.7	38%	0.38	11%	0.111	S	C	.	.	H	α-helix	trans	-72.6	-22.7	-179.3	-68.8	-28.5	0	0	0	113.9	P229 S230 Y330 C336	P229-N332 WeakPolarHBondContact CA-OD1 3.42Å; S230-N332 PolarHBondContact N-OD1 3.39Å; S230-N332 PolarHBondContact OG-ND2 3.23Å; S230-N332 PolarHBondContact OG-OD1 3.47Å; Y330-N332 VanDerWaalsContact C-N 3.3Å; Y330-N332 PolarHBondContact O-N 3.47Å; N332-C336 WeakPolarHBondContact O-CB 3.44Å
333	E	91.3	Very high	92.2	Very high	55 Å²	55	27.1 Å²	27.1	26%	0.257	14%	0.135	S	C	.	.	H	α-helix	trans	-101.6	-56.2	-179.6	-64.6	-176.5	-114.8	0	0	110.6	Y330 P331 V345 C352 I355 K359	Y330-E333 PolarHBondContact O-N 2.93Å; P331-E333 VanDerWaalsContact C-N 3.31Å; P331-E333 PolarHBondContact O-N 3.41Å; E333-V345 HydrophobicContact CB-CG1 3.91Å; E333-V345 HydrophobicContact CG-CG1 4.24Å; E333-V345 HydrophobicContact CG-CG2 4.36Å; E333-C352 WeakPolarHBondContact O-CB 3.3Å; E333-I355 HydrophobicContact CB-CD1 4.32Å; E333-K359 VanDerWaalsContact OE1-CE 3.28Å; E333-K359 WeakPolarHBondContact OE1-CE 3.28Å; E333-K359 IonicContact OE1-NZ 3.03Å; E333-K359 PolarHBondContact OE1-NZ 3.41Å; E333-K359 WeakPolarHBondContact OE2-CE 3.29Å; E333-K359 IonicContact OE2-NZ 2.8Å; E333-K359 PolarHBondContact OE2-NZ 3.49Å
334	V	92.8	Very high	91.7	Very high	5 Å²	5	34.5 Å²	34.5	3%	0.03	17%	0.169	C	C	.	.	H	α-helix	trans	-75.3	-38	-175.4	176.9	0	0	0	0	111.6	A80 R327 Y330 S353 I355 A356	A80-V334 HydrophobicContact CB-CG1 3.94Å; R327-V334 HydrophobicContact CB-CG1 4.21Å; Y330-V334 WeakPolarHBondContact O-CB 3.44Å; Y330-V334 PolarHBondContact O-N 3.14Å; V334-S353 PolarHBondContact O-N 3.28Å; V334-I355 HydrophobicContact CG2-CG1 4.03Å; V334-A356 HydrophobicContact CG1-CB 3.81Å
335	G	89.6	Confident	91.1	Very high	8 Å²	8	36.3 Å²	36.3	8%	0.082	18%	0.18	C	C	.	.	T	Hydrogen-bonded Turn	trans	-94.4	14.3	178.7	0	0	0	0	0	113.8	P229 P331	P229-G335 WeakPolarHBondContact CG-O 3.1Å; P331-G335 CarbonylContact O-C 3.05Å; P331-G335 VanDerWaalsContact O-C 3.3Å; P331-G335 WeakPolarHBondContact O-CA 3.39Å; P331-G335 PolarHBondContact O-N 3.45Å
336	C	89.7	Confident	90.4	Very high	8 Å²	8	37 Å²	37	5%	0.054	19%	0.185	C	C	.	.			trans	-59.2	141.4	-178.8	79.8	0	0	0	0	111.1	N332 C342 C352	N332-C336 WeakPolarHBondContact O-CB 3.44Å; C336-C342 HydrophobicContact CB-CB 4.37Å; C336-C342 WeakPolarHBondContact CB-SG 3.05Å; C336-C342 PolarHBondContact O-SG 3.44Å; C336-C342 WeakPolarHBondContact SG-CA 3.17Å; C336-C342 WeakPolarHBondContact SG-CB 3.34Å; C336-C342 CovalentContact SG-SG 2.05Å; C336-C342 PolarHBondContact SG-SG 3.44Å; C336-C352 PolarHBondContact SG-SG 3.46Å
337	V	87.1	Confident	89.6	Confident	11 Å²	11	39.2 Å²	39.2	7%	0.067	21%	0.208	C	C	.	.			trans	-128.1	-12	176.5	-64.2	0	0	0	0	113.3	P229 F232 I242 C246 Y247 P339 I503	P229-V337 HydrophobicContact CG-CG2 4.48Å; F232-V337 HydrophobicContact CB-CG2 4.46Å; I242-V337 HydrophobicContact CD1-CG2 4.46Å; I242-V337 HydrophobicContact CG2-CB 4.29Å; I242-V337 HydrophobicContact CG2-CG2 4.05Å; C246-V337 HydrophobicContact CB-CG1 4.33Å; C246-V337 WeakPolarHBondContact O-CG1 3.49Å; Y247-V337 HydrophobicContact CD1-CG2 4.44Å; V337-P339 WeakPolarHBondContact O-CD 3.27Å; V337-I503 WeakPolarHBondContact O-CD1 3.26Å
338	V	87.9	Confident	88.8	Confident	7 Å²	7	39.8 Å²	39.8	4%	0.042	21%	0.213	C	C	.	.			trans	-84.6	118.6	-179.2	177.2	0	0	0	0	108.2	N231 I242 E340 I341 C342	N231-V338 HydrophobicContact CB-CG2 4.46Å; N231-V338 WeakPolarHBondContact O-CG2 3.39Å; I242-V338 HydrophobicContact CD1-CG2 4.29Å; V338-E340 VanDerWaalsContact C-N 3.28Å; V338-E340 WeakPolarHBondContact CG1-OE2 3.37Å; V338-E340 PolarHBondContact O-N 2.82Å; V338-I341 HydrophobicContact CB-CB 4.29Å; V338-I341 HydrophobicContact CB-CD1 3.98Å; V338-I341 HydrophobicContact CB-CG1 4.13Å; V338-I341 HydrophobicContact CG1-CD1 4.13Å; V338-I341 HydrophobicContact CG1-CG1 4.05Å; V338-I341 HydrophobicContact CG2-CD1 4.39Å; V338-I341 PolarHBondContact O-N 3.05Å; V338-I341 VanDerWaalsContact O-N 3.13Å; V338-C342 PolarHBondContact O-N 3.17Å; V338-C342 PolarHBondContact O-SG 3.31Å; V338-C342 VanDerWaalsContact O-SG 3.42Å
339	P	86.4	Confident	88.1	Confident	3 Å²	3	42 Å²	42	2%	0.019	22%	0.223	C	C	.	.	H	α-helix	trans	-52.8	-41	-173	-30.7	36.7	0	0	0	114.4	Y240 V337 K343 E349 I503	Y240-P339 HydrophobicContact CD1-CG 4.09Å; Y240-P339 HydrophobicContact CD2-CG 4.34Å; Y240-P339 HydrophobicContact CE1-CG 4.08Å; Y240-P339 HydrophobicContact CE2-CG 4.3Å; Y240-P339 HydrophobicContact CG-CG 4.23Å; V337-P339 WeakPolarHBondContact O-CD 3.27Å; P339-K343 VanDerWaalsContact O-CB 3.24Å; P339-K343 WeakPolarHBondContact O-CB 3.4Å; P339-K343 PolarHBondContact O-N 3.4Å; P339-E349 HydrophobicContact CB-CB 4.14Å; P339-E349 HydrophobicContact CB-CG 4.39Å; P339-I503 HydrophobicContact CG-CD1 4.3Å; P339-I503 HydrophobicContact CG-CG2 4.32Å
340	E	87.2	Confident	87.2	Confident	72 Å²	72	41.5 Å²	41.5	34%	0.336	22%	0.222	S	C	.	.	H	α-helix	trans	-65	-44.4	-178.4	-60.3	77.2	-166.6	0	0	111.5	Y240 V338 E344	Y240-E340 WeakPolarHBondContact CE2-OE1 2.96Å; V338-E340 VanDerWaalsContact C-N 3.28Å; V338-E340 WeakPolarHBondContact CG1-OE2 3.37Å; V338-E340 PolarHBondContact O-N 2.82Å; E340-E344 PolarHBondContact O-N 2.99Å
341	I	87.7	Confident	86.7	Confident	45 Å²	45	39.5 Å²	39.5	23%	0.231	22%	0.217	C	C	.	.	H	α-helix	trans	-69.1	-46.2	178.7	-59.3	178.4	0	0	0	110	N231 V338 K343 E344 V345	N231-I341 HydrophobicContact CB-CD1 3.58Å; N231-I341 WeakPolarHBondContact ND2-CD1 3.4Å; V338-I341 HydrophobicContact CB-CB 4.29Å; V338-I341 HydrophobicContact CB-CD1 3.98Å; V338-I341 HydrophobicContact CB-CG1 4.13Å; V338-I341 HydrophobicContact CG1-CD1 4.13Å; V338-I341 HydrophobicContact CG1-CG1 4.05Å; V338-I341 HydrophobicContact CG2-CD1 4.39Å; V338-I341 PolarHBondContact O-N 3.05Å; V338-I341 VanDerWaalsContact O-N 3.13Å; I341-K343 VanDerWaalsContact C-N 3.26Å; I341-K343 PolarHBondContact O-N 3.18Å; I341-E344 WeakPolarHBondContact O-CB 3.47Å; I341-E344 PolarHBondContact O-N 3.39Å; I341-E344 VanDerWaalsContact O-N 3.14Å; I341-V345 HydrophobicContact CG2-CG2 4.25Å; I341-V345 WeakPolarHBondContact O-CG2 3.3Å; I341-V345 PolarHBondContact O-N 3.27Å
342	C	87.8	Confident	86.5	Confident	0 Å²	0	38.2 Å²	38.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-61.9	-37	179.4	-67.1	0	0	0	0	112	C336 V338 E344 V345 C346 G347 T348 C352	C336-C342 HydrophobicContact CB-CB 4.37Å; C336-C342 WeakPolarHBondContact CB-SG 3.05Å; C336-C342 PolarHBondContact O-SG 3.44Å; C336-C342 WeakPolarHBondContact SG-CA 3.17Å; C336-C342 WeakPolarHBondContact SG-CB 3.34Å; C336-C342 CovalentContact SG-SG 2.05Å; C336-C342 PolarHBondContact SG-SG 3.44Å; V338-C342 PolarHBondContact O-N 3.17Å; V338-C342 PolarHBondContact O-SG 3.31Å; V338-C342 VanDerWaalsContact O-SG 3.42Å; C342-E344 VanDerWaalsContact C-N 3.32Å; C342-E344 PolarHBondContact O-N 3.41Å; C342-V345 PolarHBondContact O-N 3.42Å; C342-C346 PolarHBondContact O-N 3Å; C342-C346 PolarHBondContact O-SG 3.3Å; C342-C346 VanDerWaalsContact O-SG 3.37Å; C342-G347 PolarHBondContact O-N 3.47Å; C342-T348 CarbonylContact C-O 3.6Å; C342-T348 WeakPolarHBondContact CB-O 3.15Å; C342-C352 PolarHBondContact O-SG 2.82Å
343	K	86.9	Confident	86.5	Confident	115 Å²	115	35.4 Å²	35.4	50%	0.5	20%	0.195	S	C	.	.	H	α-helix	trans	-65.3	-36.9	176.1	-169.2	174.7	-167.6	161.2	0	112.2	P339 I341 G347 T348 E349	P339-K343 VanDerWaalsContact O-CB 3.24Å; P339-K343 WeakPolarHBondContact O-CB 3.4Å; P339-K343 PolarHBondContact O-N 3.4Å; I341-K343 VanDerWaalsContact C-N 3.26Å; I341-K343 PolarHBondContact O-N 3.18Å; K343-G347 WeakPolarHBondContact O-CA 3.45Å; K343-G347 PolarHBondContact O-N 3.32Å; K343-T348 PolarHBondContact N-O 3.49Å; K343-T348 VanDerWaalsContact N-O 3.16Å; K343-E349 HydrophobicContact CB-CG 4.26Å; K343-E349 HydrophobicContact CD-CG 4.06Å; K343-E349 HydrophobicContact CG-CG 4.45Å; K343-E349 IonicContact NZ-OE1 2.73Å; K343-E349 PolarHBondContact NZ-OE1 3.41Å
344	E	86.3	Confident	86.5	Confident	155 Å²	155	33.2 Å²	33.2	72%	0.724	19%	0.185	S	C	*	.	H	α-helix	trans	-67.8	-44.2	174.5	-173.3	177.2	-178.5	0	0	112	E340 I341 C342	E340-E344 PolarHBondContact O-N 2.99Å; I341-E344 WeakPolarHBondContact O-CB 3.47Å; I341-E344 PolarHBondContact O-N 3.39Å; I341-E344 VanDerWaalsContact O-N 3.14Å; C342-E344 VanDerWaalsContact C-N 3.32Å; C342-E344 PolarHBondContact O-N 3.41Å
345	V	85.6	Confident	86.4	Confident	37 Å²	37	33.1 Å²	33.1	22%	0.224	18%	0.184	C	C	.	.	H	α-helix	trans	-73.1	-47.6	-174.9	172.2	0	0	0	0	112.7	E333 I341 C342 C352 I355	E333-V345 HydrophobicContact CB-CG1 3.91Å; E333-V345 HydrophobicContact CG-CG1 4.24Å; E333-V345 HydrophobicContact CG-CG2 4.36Å; I341-V345 HydrophobicContact CG2-CG2 4.25Å; I341-V345 WeakPolarHBondContact O-CG2 3.3Å; I341-V345 PolarHBondContact O-N 3.27Å; C342-V345 PolarHBondContact O-N 3.42Å; V345-C352 HydrophobicContact CG1-CB 4.49Å; V345-I355 HydrophobicContact CG1-CD1 3.56Å
346	C	82.9	Confident	86.7	Confident	14 Å²	14	32.8 Å²	32.8	10%	0.095	18%	0.18	C	C	.	.	H	α-helix	trans	-130.8	4.9	-172.3	71.6	0	0	0	0	114.8	C342 T348 C352 I355	C342-C346 PolarHBondContact O-N 3Å; C342-C346 PolarHBondContact O-SG 3.3Å; C342-C346 VanDerWaalsContact O-SG 3.37Å; C346-T348 VanDerWaalsContact C-N 3.28Å; C346-T348 PolarHBondContact O-N 2.84Å; C346-T348 PolarHBondContact SG-OG1 2.89Å; C346-C352 HydrophobicContact CB-CB 3.72Å; C346-C352 WeakPolarHBondContact CB-SG 3.38Å; C346-C352 WeakPolarHBondContact SG-CA 3.49Å; C346-C352 WeakPolarHBondContact SG-CB 3.35Å; C346-C352 CovalentContact SG-SG 2.03Å; C346-C352 PolarHBondContact SG-SG 3.33Å; C346-I355 HydrophobicContact CB-CG2 3.72Å
347	G	80.6	Confident	86.9	Confident	48 Å²	48	32.4 Å²	32.4	50%	0.495	18%	0.178	S	C	.	.	S	Bend	trans	74	14.4	178.6	0	0	0	0	0	114.6	C342 K343	C342-G347 PolarHBondContact O-N 3.47Å; K343-G347 WeakPolarHBondContact O-CA 3.45Å; K343-G347 PolarHBondContact O-N 3.32Å
348	T	80.6	Confident	87.1	Confident	27 Å²	27	31.9 Å²	31.9	17%	0.166	18%	0.175	C	C	.	.			trans	-131.8	145.3	178.1	71.7	0	0	0	0	111.5	C342 K343 C346 G351	C342-T348 CarbonylContact C-O 3.6Å; C342-T348 WeakPolarHBondContact CB-O 3.15Å; K343-T348 PolarHBondContact N-O 3.49Å; K343-T348 VanDerWaalsContact N-O 3.16Å; C346-T348 VanDerWaalsContact C-N 3.28Å; C346-T348 PolarHBondContact O-N 2.84Å; C346-T348 PolarHBondContact SG-OG1 2.89Å; T348-G351 PolarHBondContact OG1-O 3.26Å
349	E	81.6	Confident	87.3	Confident	71 Å²	71	33.1 Å²	33.1	33%	0.332	18%	0.179	S	C	.	.	S	Bend	trans	-89.8	-8.9	-175.4	-69.8	174.6	-170.9	0	0	113.3	P339 K343 I503	P339-E349 HydrophobicContact CB-CB 4.14Å; P339-E349 HydrophobicContact CB-CG 4.39Å; K343-E349 HydrophobicContact CB-CG 4.26Å; K343-E349 HydrophobicContact CD-CG 4.06Å; K343-E349 HydrophobicContact CG-CG 4.45Å; K343-E349 IonicContact NZ-OE1 2.73Å; K343-E349 PolarHBondContact NZ-OE1 3.41Å; E349-I503 WeakPolarHBondContact O-CD1 3.35Å
350	V	77.3	Confident	87.6	Confident	39 Å²	39	33 Å²	33	24%	0.236	18%	0.178	C	C	.	.	S	Bend	trans	-101	-7.4	-168.7	-68.1	0	0	0	0	114.4	F504	V350-F504 HydrophobicContact CG1-CD2 4.22Å; V350-F504 HydrophobicContact CG1-CE2 4.33Å
351	G	85.6	Confident	87.9	Confident	10 Å²	10	29.5 Å²	29.5	10%	0.103	16%	0.162	C	C	.	.			trans	130.5	150.5	178.6	0	0	0	0	0	113.1	T348	T348-G351 PolarHBondContact OG1-O 3.26Å
352	C	89.6	Confident	87.9	Confident	2 Å²	2	28 Å²	28	1%	0.014	16%	0.155	C	C	.	.			trans	-109.7	19.7	-171.3	-64.1	0	0	0	0	114.6	E333 C336 C342 V345 C346 N354 I355	E333-C352 WeakPolarHBondContact O-CB 3.3Å; C336-C352 PolarHBondContact SG-SG 3.46Å; C342-C352 PolarHBondContact O-SG 2.82Å; V345-C352 HydrophobicContact CG1-CB 4.49Å; C346-C352 HydrophobicContact CB-CB 3.72Å; C346-C352 WeakPolarHBondContact CB-SG 3.38Å; C346-C352 WeakPolarHBondContact SG-CA 3.49Å; C346-C352 WeakPolarHBondContact SG-CB 3.35Å; C346-C352 CovalentContact SG-SG 2.03Å; C346-C352 PolarHBondContact SG-SG 3.33Å; C352-N354 PolarHBondContact O-N 2.9Å; C352-I355 HydrophobicContact CB-CD1 4.08Å; C352-I355 HydrophobicContact CB-CG1 4.47Å; C352-I355 VanDerWaalsContact O-CG1 3.3Å; C352-I355 WeakPolarHBondContact O-CG1 3.08Å; C352-I355 PolarHBondContact O-N 3.36Å
353	S	91.8	Very high	88	Confident	11 Å²	11	30.7 Å²	30.7	8%	0.077	17%	0.172	C	C	.	.	G	3₁₀ helix	trans	-52.5	-34.9	-175.5	72.3	0	0	0	0	113.9	G77 V334 I355 A356 G441	G77-S353 WeakPolarHBondContact CA-O 3.26Å; G77-S353 WeakPolarHBondContact O-CB 3.5Å; V334-S353 PolarHBondContact O-N 3.28Å; S353-I355 PolarHBondContact O-N 2.58Å; S353-I355 VanDerWaalsContact O-N 3.11Å; S353-A356 WeakPolarHBondContact O-CB 3.34Å; S353-A356 PolarHBondContact O-N 2.83Å; S353-G441 PolarHBondContact OG-O 3.41Å
354	N	91.1	Very high	88.2	Confident	10 Å²	10	26.1 Å²	26.1	5%	0.053	15%	0.153	C	C	.	.	G	3₁₀ helix	trans	-59.1	-21.5	178.4	-68.2	-41.2	0	0	0	114.2	V73 C352 A356 G441 L443	V73-N354 HydrophobicContact CG1-CB 3.72Å; V73-N354 WeakPolarHBondContact CG1-O 3.48Å; C352-N354 PolarHBondContact O-N 2.9Å; N354-A356 PolarHBondContact O-N 3.32Å; N354-G441 PolarHBondContact ND2-O 3.28Å; N354-L443 PolarHBondContact OD1-N 2.64Å
355	I	92.1	Very high	88.4	Confident	3 Å²	3	19.2 Å²	19.2	2%	0.015	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	-78.7	-7.7	177.8	81.8	-174.9	0	0	0	112.9	V155 Q159 E333 V334 V345 C346 C352 S353 Y357 P358 K359	V155-I355 HydrophobicContact CG1-CG2 4.15Å; Q159-I355 HydrophobicContact CG-CB 4.33Å; Q159-I355 HydrophobicContact CG-CG2 4.38Å; E333-I355 HydrophobicContact CB-CD1 4.32Å; V334-I355 HydrophobicContact CG2-CG1 4.03Å; V345-I355 HydrophobicContact CG1-CD1 3.56Å; C346-I355 HydrophobicContact CB-CG2 3.72Å; C352-I355 HydrophobicContact CB-CD1 4.08Å; C352-I355 HydrophobicContact CB-CG1 4.47Å; C352-I355 VanDerWaalsContact O-CG1 3.3Å; C352-I355 WeakPolarHBondContact O-CG1 3.08Å; C352-I355 PolarHBondContact O-N 3.36Å; S353-I355 PolarHBondContact O-N 2.58Å; S353-I355 VanDerWaalsContact O-N 3.11Å; I355-Y357 PolarHBondContact O-N 3.25Å; I355-P358 VanDerWaalsContact O-CD 3.27Å; I355-P358 WeakPolarHBondContact O-CD 3.37Å; I355-K359 VanDerWaalsContact O-CB 3.24Å; I355-K359 WeakPolarHBondContact O-CB 3.48Å; I355-K359 PolarHBondContact O-N 2.94Å
356	A	94.3	Very high	88.6	Confident	0 Å²	0	20 Å²	20	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-49.7	-53.3	-170.9	0	0	0	0	0	113.4	A80 S326 V334 S353 N354 L360	A80-A356 HydrophobicContact CB-CB 3.76Å; S326-A356 VanDerWaalsContact CB-O 3.23Å; S326-A356 WeakPolarHBondContact CB-O 3.35Å; S326-A356 VanDerWaalsContact OG-C 3.32Å; S326-A356 WeakPolarHBondContact OG-CA 3.27Å; S326-A356 PolarHBondContact OG-O 3.41Å; V334-A356 HydrophobicContact CG1-CB 3.81Å; S353-A356 WeakPolarHBondContact O-CB 3.34Å; S353-A356 PolarHBondContact O-N 2.83Å; N354-A356 PolarHBondContact O-N 3.32Å; A356-L360 PolarHBondContact O-N 3.4Å
357	Y	94.1	Very high	88.7	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-72.1	-49.4	-178.6	-162.3	-81.3	0	0	0	113.3	F72 A76 L206 L318 M319 P322 I355 K359 L360 V361 M373 M377	F72-Y357 HydrophobicContact CB-CD1 4.26Å; F72-Y357 AromaticContact CD1-CD1 3.72Å; F72-Y357 HydrophobicContact CD1-CD1 3.72Å; F72-Y357 HydrophobicContact CD1-CD2 4.19Å; F72-Y357 AromaticContact CD1-CE1 3.3Å; F72-Y357 HydrophobicContact CD1-CE1 3.3Å; F72-Y357 AromaticContact CD1-CE2 3.82Å; F72-Y357 HydrophobicContact CD1-CE2 3.82Å; F72-Y357 HydrophobicContact CD1-CG 4.14Å; F72-Y357 AromaticContact CD1-CZ 3.36Å; F72-Y357 AromaticContact CE1-CE1 3.71Å; F72-Y357 HydrophobicContact CE1-CE1 3.71Å; F72-Y357 HydrophobicContact CE1-CE2 4.12Å; F72-Y357 AromaticContact CE1-CZ 3.45Å; F72-Y357 VanDerWaalsContact CE1-CZ 3.45Å; F72-Y357 WeakPolarHBondContact CE1-OH 3.26Å; F72-Y357 HydrophobicContact CG-CD1 4.39Å; F72-Y357 HydrophobicContact CG-CE1 4.26Å; F72-Y357 WeakPolarHBondContact O-CB 3.34Å; A76-Y357 HydrophobicContact CB-CD2 3.94Å; A76-Y357 HydrophobicContact CB-CG 4.28Å; L206-Y357 HydrophobicContact CD2-CD1 4.34Å; L206-Y357 HydrophobicContact CD2-CD2 4.34Å; L206-Y357 HydrophobicContact CD2-CE1 3.68Å; L206-Y357 HydrophobicContact CD2-CE2 3.67Å; L206-Y357 WeakPolarHBondContact CD2-OH 3.38Å; L318-Y357 WeakPolarHBondContact O-CE2 2.97Å; M319-Y357 HydrophobicContact CG-CE2 4.47Å; P322-Y357 HydrophobicContact CB-CD2 4.14Å; P322-Y357 HydrophobicContact CB-CE2 4.06Å; P322-Y357 HydrophobicContact CG-CE2 4.48Å; I355-Y357 PolarHBondContact O-N 3.25Å; Y357-K359 PolarHBondContact O-N 3.2Å; Y357-L360 PolarHBondContact O-N 2.9Å; Y357-V361 HydrophobicContact CD1-CG2 3.89Å; Y357-V361 HydrophobicContact CE1-CG2 3.67Å; Y357-V361 PolarHBondContact O-N 2.99Å; Y357-V361 VanDerWaalsContact O-N 3.12Å; Y357-M373 HydrophobicContact CE1-CE 3.82Å; Y357-M373 VanDerWaalsContact OH-CE 3.23Å; Y357-M373 WeakPolarHBondContact OH-CE 2.93Å; Y357-M377 HydrophobicContact CD1-CE 3.91Å; Y357-M377 HydrophobicContact CD1-SD 4.16Å; Y357-M377 HydrophobicContact CE1-CE 4.02Å; Y357-M377 HydrophobicContact CE1-SD 3.79Å
358	P	91.9	Very high	88.9	Confident	1 Å²	1	21.3 Å²	21.3	1%	0.006	13%	0.131	C	C	.	.	H	α-helix	trans	-53.1	-41.7	173.6	-12	9.3	0	0	0	113.2	V73 V155 F156 Q159 I355 L360 V361 V362	V73-P358 HydrophobicContact CG2-CG 4.36Å; V155-P358 HydrophobicContact CG1-CG 4.49Å; F156-P358 HydrophobicContact CD2-CB 3.69Å; F156-P358 HydrophobicContact CD2-CG 3.8Å; F156-P358 HydrophobicContact CE2-CB 3.94Å; F156-P358 HydrophobicContact CE2-CG 4.36Å; Q159-P358 HydrophobicContact CB-CB 3.83Å; Q159-P358 HydrophobicContact CG-CB 4.05Å; I355-P358 VanDerWaalsContact O-CD 3.27Å; I355-P358 WeakPolarHBondContact O-CD 3.37Å; P358-L360 PolarHBondContact O-N 3.13Å; P358-V361 PolarHBondContact O-N 3.11Å; P358-V362 WeakPolarHBondContact O-CG2 3.45Å; P358-V362 PolarHBondContact O-N 3.35Å
359	K	91.9	Very high	89.2	Confident	32 Å²	32	23.4 Å²	23.4	14%	0.139	14%	0.141	C	C	.	.	H	α-helix	trans	-58.2	-49.7	179.5	-174.4	68.9	175.6	-166.5	0	111.1	Y330 E333 I355 Y357 V361 V362 T363	Y330-K359 HydrophobicContact CD2-CG 3.6Å; Y330-K359 HydrophobicContact CE2-CG 3.91Å; Y330-K359 HydrophobicContact CG-CG 3.99Å; E333-K359 VanDerWaalsContact OE1-CE 3.28Å; E333-K359 WeakPolarHBondContact OE1-CE 3.28Å; E333-K359 IonicContact OE1-NZ 3.03Å; E333-K359 PolarHBondContact OE1-NZ 3.41Å; E333-K359 WeakPolarHBondContact OE2-CE 3.29Å; E333-K359 IonicContact OE2-NZ 2.8Å; E333-K359 PolarHBondContact OE2-NZ 3.49Å; I355-K359 VanDerWaalsContact O-CB 3.24Å; I355-K359 WeakPolarHBondContact O-CB 3.48Å; I355-K359 PolarHBondContact O-N 2.94Å; Y357-K359 PolarHBondContact O-N 3.2Å; K359-V361 PolarHBondContact O-N 2.89Å; K359-V362 PolarHBondContact O-N 3.19Å; K359-T363 HydrophobicContact CD-CG2 4.12Å; K359-T363 WeakPolarHBondContact O-CG2 3.47Å; K359-T363 PolarHBondContact O-N 3.2Å; K359-T363 PolarHBondContact O-OG1 2.95Å
360	L	93.1	Very high	89.5	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-59.3	-43.3	176.5	-77.4	177	0	0	0	112.9	L206 P322 L329 Y330 A356 Y357 P358 V362 T363 V364	L206-L360 HydrophobicContact CD1-CB 4.26Å; L206-L360 HydrophobicContact CD2-CB 4.49Å; P322-L360 HydrophobicContact CB-CD1 3.92Å; P322-L360 WeakPolarHBondContact O-CD1 3.41Å; L329-L360 HydrophobicContact CD1-CD2 3.86Å; Y330-L360 HydrophobicContact CE2-CD2 4.19Å; A356-L360 PolarHBondContact O-N 3.4Å; Y357-L360 PolarHBondContact O-N 2.9Å; P358-L360 PolarHBondContact O-N 3.13Å; L360-V362 VanDerWaalsContact C-N 3.27Å; L360-V362 PolarHBondContact O-N 3.33Å; L360-T363 PolarHBondContact O-N 3.17Å; L360-V364 HydrophobicContact CD2-CG2 3.71Å; L360-V364 VanDerWaalsContact O-CB 3.26Å; L360-V364 WeakPolarHBondContact O-CB 3.32Å; L360-V364 PolarHBondContact O-N 3.42Å
361	V	92.4	Very high	90	Very high	0 Å²	0	20 Å²	20	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-59.5	-42.6	178.8	171.9	0	0	0	0	110.7	L206 Y357 P358 K359 M365 M373 L374 M377	L206-V361 HydrophobicContact CD1-CG2 4.24Å; L206-V361 HydrophobicContact CD2-CG2 3.72Å; Y357-V361 HydrophobicContact CD1-CG2 3.89Å; Y357-V361 HydrophobicContact CE1-CG2 3.67Å; Y357-V361 PolarHBondContact O-N 2.99Å; Y357-V361 VanDerWaalsContact O-N 3.12Å; P358-V361 PolarHBondContact O-N 3.11Å; K359-V361 PolarHBondContact O-N 2.89Å; V361-M365 HydrophobicContact CB-SD 4.48Å; V361-M365 HydrophobicContact CG1-SD 3.97Å; V361-M365 WeakPolarHBondContact O-CB 3.41Å; V361-M373 HydrophobicContact CG1-CB 4Å; V361-M373 HydrophobicContact CG1-CG 3.84Å; V361-M373 HydrophobicContact CG2-CG 3.99Å; V361-L374 HydrophobicContact CG1-CD2 3.9Å; V361-L374 HydrophobicContact CG1-CG 4.2Å; V361-M377 HydrophobicContact CG2-SD 4.31Å
362	V	89.4	Confident	90.1	Very high	14 Å²	14	22.3 Å²	22.3	9%	0.085	13%	0.13	C	C	.	.	H	α-helix	trans	-76.2	-33.5	-174.4	175.5	0	0	0	0	112.7	V9 P358 K359 L360 R370 L374	V9-V362 HydrophobicContact CB-CG1 3.67Å; V9-V362 HydrophobicContact CG1-CG1 3.45Å; V9-V362 VanDerWaalsContact CG1-CG1 3.45Å; V9-V362 HydrophobicContact CG2-CG1 4.17Å; P358-V362 WeakPolarHBondContact O-CG2 3.45Å; P358-V362 PolarHBondContact O-N 3.35Å; K359-V362 PolarHBondContact O-N 3.19Å; L360-V362 VanDerWaalsContact C-N 3.27Å; L360-V362 PolarHBondContact O-N 3.33Å; V362-R370 WeakPolarHBondContact O-CD 3.42Å; V362-R370 PolarHBondContact O-NH1 3.09Å; V362-L374 HydrophobicContact CG2-CD2 4.37Å
363	T	89.4	Confident	90	Very high	55 Å²	55	22.4 Å²	22.4	34%	0.337	13%	0.131	S	C	.	.	H	α-helix	trans	-100.3	-32.2	-172.4	59	0	0	0	0	114.7	Y330 K359 L360	Y330-T363 WeakPolarHBondContact CE2-OG1 3.46Å; Y330-T363 VanDerWaalsContact CZ-OG1 3.28Å; Y330-T363 WeakPolarHBondContact OH-CB 3.44Å; Y330-T363 PolarHBondContact OH-OG1 3.23Å; K359-T363 HydrophobicContact CD-CG2 4.12Å; K359-T363 WeakPolarHBondContact O-CG2 3.47Å; K359-T363 PolarHBondContact O-N 3.2Å; K359-T363 PolarHBondContact O-OG1 2.95Å; L360-T363 PolarHBondContact O-N 3.17Å
364	V	91.2	Very high	89.8	Confident	19 Å²	19	22 Å²	22	12%	0.115	13%	0.128	C	C	.	.	H	α-helix	trans	-97.1	-30.6	-173.9	178.1	0	0	0	0	112	F209 E213 L329 L360	F209-V364 HydrophobicContact CB-CG1 3.66Å; E213-V364 HydrophobicContact CG-CG1 4.03Å; E213-V364 HydrophobicContact CG-CG2 4.47Å; L329-V364 HydrophobicContact CD1-CG2 4.29Å; L360-V364 HydrophobicContact CD2-CG2 3.71Å; L360-V364 VanDerWaalsContact O-CB 3.26Å; L360-V364 WeakPolarHBondContact O-CB 3.32Å; L360-V364 PolarHBondContact O-N 3.42Å
365	M	89.8	Confident	89.6	Confident	11 Å²	11	21.5 Å²	21.5	5%	0.054	13%	0.125	C	C	.	.	S	Bend	trans	-77	137.9	-178.7	-67.3	-173.2	134.3	0	0	112.3	G202 V205 L206 V361 R370 M373	G202-M365 WeakPolarHBondContact O-CE 3.46Å; V205-M365 HydrophobicContact CG1-CE 4.32Å; L206-M365 HydrophobicContact CB-CE 3.57Å; L206-M365 HydrophobicContact CD1-CE 3.92Å; L206-M365 HydrophobicContact CD1-CG 3.58Å; L206-M365 HydrophobicContact CD1-SD 3.98Å; L206-M365 HydrophobicContact CG-CE 4.32Å; V361-M365 HydrophobicContact CB-SD 4.48Å; V361-M365 HydrophobicContact CG1-SD 3.97Å; V361-M365 WeakPolarHBondContact O-CB 3.41Å; M365-R370 HydrophobicContact CB-CB 3.92Å; M365-M373 HydrophobicContact CE-CB 4.11Å; M365-M373 HydrophobicContact CE-CG 4.08Å; M365-M373 HydrophobicContact CE-SD 4.49Å; M365-M373 HydrophobicContact SD-CB 3.54Å; M365-M373 VanDerWaalsContact SD-CB 3.54Å; M365-M373 HydrophobicContact SD-CG 3.78Å
366	P	89.3	Confident	89.4	Confident	53 Å²	53	21.4 Å²	21.4	34%	0.344	13%	0.125	S	C	.	.	P	Polyproline II helix	trans	-69.7	161.2	174.8	31	-35.6	0	0	0	111.3	F209 L369 R370	F209-P366 HydrophobicContact CE2-CG 4.49Å; F209-P366 HydrophobicContact CZ-CG 4.22Å; P366-L369 HydrophobicContact CG-CB 4.21Å; P366-L369 HydrophobicContact CG-CD1 3.87Å; P366-L369 HydrophobicContact CG-CG 4.45Å; P366-L369 PolarHBondContact O-N 3.33Å; P366-R370 WeakPolarHBondContact O-CB 3.35Å; P366-R370 PolarHBondContact O-N 2.88Å
367	S	85.9	Confident	89.1	Confident	74 Å²	74	21.6 Å²	21.6	52%	0.517	13%	0.126	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.5	144.2	175.8	55.2	0	0	0	0	112.4	N13 L369	N13-S367 WeakPolarHBondContact ND2-CB 3.27Å; S367-L369 VanDerWaalsContact C-N 3.28Å; S367-L369 PolarHBondContact O-N 2.86Å
368	G	84.9	Confident	88.7	Confident	15 Å²	15	23.3 Å²	23.3	16%	0.155	14%	0.135	C	C	.	.	T	Hydrogen-bonded Turn	trans	87.1	-57.7	-172.6	0	0	0	0	0	111.6	D16 G371 L372	D16-G368 WeakPolarHBondContact OD1-CA 3.43Å; D16-G368 PolarHBondContact OD1-N 3.26Å; G368-G371 PolarHBondContact O-N 3.37Å; G368-L372 PolarHBondContact O-N 3.04Å
369	L	86.8	Confident	88.4	Confident	72 Å²	72	23.5 Å²	23.5	38%	0.377	14%	0.136	S	C	.	.	H	α-helix	trans	-67.6	-38.2	176.3	-75	178.1	0	0	0	112	V205 F209 P366 S367 L372 M373	V205-L369 HydrophobicContact CG1-CD1 4.08Å; F209-L369 HydrophobicContact CE2-CD1 4.45Å; P366-L369 HydrophobicContact CG-CB 4.21Å; P366-L369 HydrophobicContact CG-CD1 3.87Å; P366-L369 HydrophobicContact CG-CG 4.45Å; P366-L369 PolarHBondContact O-N 3.33Å; S367-L369 VanDerWaalsContact C-N 3.28Å; S367-L369 PolarHBondContact O-N 2.86Å; L369-L372 PolarHBondContact O-N 3.47Å; L369-M373 WeakPolarHBondContact O-CB 3.28Å; L369-M373 PolarHBondContact O-N 2.92Å
370	R	88.8	Confident	88.1	Confident	39 Å²	39	22 Å²	22	15%	0.147	13%	0.129	C	C	.	.	H	α-helix	trans	-55.7	-54.5	170.1	-178.3	177.1	67.3	176.9	3.2	110.7	D16 V362 M365 P366 L372 M373 L374	D16-R370 IonicContact OD2-CZ 3.43Å; D16-R370 VanDerWaalsContact OD2-CZ 3.31Å; D16-R370 IonicContact OD2-NE 3.84Å; D16-R370 PolarHBondContact OD2-NE 3.19Å; D16-R370 IonicContact OD2-NH2 2.73Å; D16-R370 PolarHBondContact OD2-NH2 2.82Å; V362-R370 WeakPolarHBondContact O-CD 3.42Å; V362-R370 PolarHBondContact O-NH1 3.09Å; M365-R370 HydrophobicContact CB-CB 3.92Å; P366-R370 WeakPolarHBondContact O-CB 3.35Å; P366-R370 PolarHBondContact O-N 2.88Å; R370-L372 VanDerWaalsContact C-N 3.32Å; R370-L372 PolarHBondContact O-N 2.9Å; R370-M373 PolarHBondContact O-N 3.48Å; R370-L374 HydrophobicContact CG-CD1 3.9Å; R370-L374 HydrophobicContact CG-CG 4.38Å; R370-L374 WeakPolarHBondContact O-CG 3.34Å; R370-L374 PolarHBondContact O-N 2.8Å
371	G	87	Confident	87.7	Confident	0 Å²	0	22 Å²	22	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-55.3	-43.6	176.3	0	0	0	0	0	113.2	D16 I20 G368 L374 A375	D16-G371 WeakPolarHBondContact OD1-CA 3.33Å; D16-G371 PolarHBondContact OD1-N 3.39Å; I20-G371 WeakPolarHBondContact CG1-O 3.5Å; G368-G371 PolarHBondContact O-N 3.37Å; G371-L374 PolarHBondContact O-N 2.84Å; G371-A375 WeakPolarHBondContact O-CB 3.12Å; G371-A375 PolarHBondContact O-N 2.81Å
372	L	87.8	Confident	87.4	Confident	57 Å²	57	22.9 Å²	22.9	30%	0.298	13%	0.134	S	C	.	.	H	α-helix	trans	-58.9	-50.4	175.3	-174.9	61.2	0	0	0	111.7	V19 Y23 V198 G368 L369 R370 L374 A375 V376	V19-L372 HydrophobicContact CG1-CB 3.65Å; V19-L372 HydrophobicContact CG1-CD1 3.92Å; V19-L372 HydrophobicContact CG1-CG 4.36Å; Y23-L372 HydrophobicContact CD2-CD1 4.26Å; V198-L372 HydrophobicContact CG1-CD1 4.38Å; V198-L372 HydrophobicContact CG1-CG 4.45Å; G368-L372 PolarHBondContact O-N 3.04Å; L369-L372 PolarHBondContact O-N 3.47Å; R370-L372 VanDerWaalsContact C-N 3.32Å; R370-L372 PolarHBondContact O-N 2.9Å; L372-L374 VanDerWaalsContact C-N 3.32Å; L372-L374 PolarHBondContact O-N 3.11Å; L372-A375 PolarHBondContact O-N 3.49Å; L372-V376 HydrophobicContact CD1-CG2 4.18Å; L372-V376 HydrophobicContact CG-CG2 4.33Å; L372-V376 WeakPolarHBondContact O-CB 3.31Å; L372-V376 WeakPolarHBondContact O-CG2 3.32Å; L372-V376 PolarHBondContact O-N 3.11Å
373	M	88.1	Confident	87.2	Confident	4 Å²	4	22.3 Å²	22.3	2%	0.02	13%	0.13	C	C	.	.	H	α-helix	trans	-62.9	-41.3	-178.4	-169.5	63.2	-177.3	0	0	111.3	F72 Y357 V361 M365 L369 R370 V376 M377	F72-M373 HydrophobicContact CE1-CE 4.2Å; F72-M373 HydrophobicContact CZ-CE 4.49Å; Y357-M373 HydrophobicContact CE1-CE 3.82Å; Y357-M373 VanDerWaalsContact OH-CE 3.23Å; Y357-M373 WeakPolarHBondContact OH-CE 2.93Å; V361-M373 HydrophobicContact CG1-CB 4Å; V361-M373 HydrophobicContact CG1-CG 3.84Å; V361-M373 HydrophobicContact CG2-CG 3.99Å; M365-M373 HydrophobicContact CE-CB 4.11Å; M365-M373 HydrophobicContact CE-CG 4.08Å; M365-M373 HydrophobicContact CE-SD 4.49Å; M365-M373 HydrophobicContact SD-CB 3.54Å; M365-M373 VanDerWaalsContact SD-CB 3.54Å; M365-M373 HydrophobicContact SD-CG 3.78Å; L369-M373 WeakPolarHBondContact O-CB 3.28Å; L369-M373 PolarHBondContact O-N 2.92Å; R370-M373 PolarHBondContact O-N 3.48Å; M373-V376 PolarHBondContact O-N 2.85Å; M373-M377 HydrophobicContact CE-CG 4.08Å; M373-M377 HydrophobicContact CE-SD 3.76Å; M373-M377 HydrophobicContact CG-SD 4.18Å; M373-M377 WeakPolarHBondContact O-CB 3.3Å; M373-M377 VanDerWaalsContact O-CG 3.28Å; M373-M377 WeakPolarHBondContact O-CG 3.29Å; M373-M377 PolarHBondContact O-N 2.96Å
374	L	86.7	Confident	87.1	Confident	3 Å²	3	19.9 Å²	19.9	2%	0.016	12%	0.116	C	C	.	.	H	α-helix	trans	-60.8	-47.1	175.3	-66.3	172.5	0	0	0	111.3	I11 F156 A160 V361 V362 R370 G371 L372 V376 M377 L378	I11-L374 HydrophobicContact CD1-CD1 3.34Å; I11-L374 HydrophobicContact CG1-CD1 3.93Å; F156-L374 HydrophobicContact CD1-CD2 4.4Å; F156-L374 HydrophobicContact CE1-CB 4.35Å; F156-L374 HydrophobicContact CE1-CD2 3.35Å; F156-L374 HydrophobicContact CE1-CG 4.42Å; F156-L374 HydrophobicContact CE2-CD2 4.45Å; F156-L374 HydrophobicContact CZ-CD2 3.39Å; A160-L374 HydrophobicContact CB-CD1 4.29Å; A160-L374 HydrophobicContact CB-CD2 3.71Å; V361-L374 HydrophobicContact CG1-CD2 3.9Å; V361-L374 HydrophobicContact CG1-CG 4.2Å; V362-L374 HydrophobicContact CG2-CD2 4.37Å; R370-L374 HydrophobicContact CG-CD1 3.9Å; R370-L374 HydrophobicContact CG-CG 4.38Å; R370-L374 WeakPolarHBondContact O-CG 3.34Å; R370-L374 PolarHBondContact O-N 2.8Å; G371-L374 PolarHBondContact O-N 2.84Å; L372-L374 VanDerWaalsContact C-N 3.32Å; L372-L374 PolarHBondContact O-N 3.11Å; L374-V376 VanDerWaalsContact C-N 3.32Å; L374-V376 PolarHBondContact O-N 2.86Å; L374-M377 PolarHBondContact O-N 3.49Å; L374-L378 VanDerWaalsContact O-CG 3.31Å; L374-L378 WeakPolarHBondContact O-CG 3.44Å; L374-L378 PolarHBondContact O-N 3.02Å
375	A	87.7	Confident	87	Confident	0 Å²	0	19 Å²	19	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-60.2	-43.3	178	0	0	0	0	0	112.1	I20 Y23 G371 L372 L378 A379	I20-A375 HydrophobicContact CB-CB 4.19Å; I20-A375 HydrophobicContact CG1-CB 3.92Å; I20-A375 HydrophobicContact CG2-CB 4.21Å; Y23-A375 HydrophobicContact CD1-CB 3.5Å; Y23-A375 VanDerWaalsContact CD1-CB 3.5Å; Y23-A375 HydrophobicContact CE1-CB 4.2Å; Y23-A375 VanDerWaalsContact CE1-O 3.3Å; Y23-A375 WeakPolarHBondContact CE1-O 3.34Å; Y23-A375 HydrophobicContact CG-CB 3.87Å; G371-A375 WeakPolarHBondContact O-CB 3.12Å; G371-A375 PolarHBondContact O-N 2.81Å; L372-A375 PolarHBondContact O-N 3.49Å; A375-L378 PolarHBondContact O-N 3.45Å; A375-A379 PolarHBondContact O-N 3.3Å
376	V	87.9	Confident	86.9	Confident	1 Å²	1	18.4 Å²	18.4	1%	0.006	11%	0.107	C	C	.	.	H	α-helix	trans	-66.7	-42.1	-177.9	170.2	0	0	0	0	111.3	Y23 V198 I199 L372 M373 L374 A379 A380	Y23-V376 HydrophobicContact CD2-CG2 4.01Å; Y23-V376 HydrophobicContact CE1-CG2 4.32Å; Y23-V376 HydrophobicContact CE2-CG2 3.5Å; V198-V376 HydrophobicContact CB-CG1 4.23Å; V198-V376 HydrophobicContact CB-CG2 3.95Å; V198-V376 HydrophobicContact CG1-CB 4.37Å; V198-V376 HydrophobicContact CG1-CG1 4.24Å; V198-V376 HydrophobicContact CG1-CG2 3.26Å; I199-V376 HydrophobicContact CB-CG1 4.21Å; I199-V376 HydrophobicContact CG1-CG1 3.36Å; L372-V376 HydrophobicContact CD1-CG2 4.18Å; L372-V376 HydrophobicContact CG-CG2 4.33Å; L372-V376 WeakPolarHBondContact O-CB 3.31Å; L372-V376 WeakPolarHBondContact O-CG2 3.32Å; L372-V376 PolarHBondContact O-N 3.11Å; M373-V376 PolarHBondContact O-N 2.85Å; L374-V376 VanDerWaalsContact C-N 3.32Å; L374-V376 PolarHBondContact O-N 2.86Å; V376-A379 PolarHBondContact O-N 3.23Å; V376-A380 WeakPolarHBondContact O-CB 3.46Å; V376-A380 PolarHBondContact O-N 3.5Å
377	M	86.9	Confident	86.8	Confident	4 Å²	4	16 Å²	16	2%	0.02	9%	0.091	C	C	.	.	H	α-helix	trans	-68	-37.4	175.9	-69.5	-175.9	66.4	0	0	112.1	F72 F156 Y357 V361 M373 L374 A380 L381	F72-M377 HydrophobicContact CB-CE 3.46Å; F72-M377 VanDerWaalsContact CB-CE 3.46Å; F72-M377 HydrophobicContact CD1-CE 3.98Å; F72-M377 HydrophobicContact CD2-CE 3.96Å; F72-M377 HydrophobicContact CG-CE 3.53Å; F156-M377 HydrophobicContact CD1-CB 4.43Å; F156-M377 HydrophobicContact CD2-CE 3.5Å; F156-M377 HydrophobicContact CD2-SD 4.27Å; F156-M377 HydrophobicContact CE1-CB 3.8Å; F156-M377 HydrophobicContact CE1-CE 4.49Å; F156-M377 HydrophobicContact CE1-SD 4.26Å; F156-M377 HydrophobicContact CE2-CB 4.33Å; F156-M377 HydrophobicContact CE2-CE 3.07Å; F156-M377 HydrophobicContact CE2-CG 4.45Å; F156-M377 HydrophobicContact CE2-SD 3.27Å; F156-M377 WeakPolarHBondContact CE2-SD 3.39Å; F156-M377 HydrophobicContact CG-CE 4.4Å; F156-M377 HydrophobicContact CZ-CB 3.73Å; F156-M377 HydrophobicContact CZ-CE 3.61Å; F156-M377 HydrophobicContact CZ-CG 4.03Å; F156-M377 HydrophobicContact CZ-SD 3.23Å; F156-M377 WeakPolarHBondContact CZ-SD 3.32Å; Y357-M377 HydrophobicContact CD1-CE 3.91Å; Y357-M377 HydrophobicContact CD1-SD 4.16Å; Y357-M377 HydrophobicContact CE1-CE 4.02Å; Y357-M377 HydrophobicContact CE1-SD 3.79Å; V361-M377 HydrophobicContact CG2-SD 4.31Å; M373-M377 HydrophobicContact CE-CG 4.08Å; M373-M377 HydrophobicContact CE-SD 3.76Å; M373-M377 HydrophobicContact CG-SD 4.18Å; M373-M377 WeakPolarHBondContact O-CB 3.3Å; M373-M377 VanDerWaalsContact O-CG 3.28Å; M373-M377 WeakPolarHBondContact O-CG 3.29Å; M373-M377 PolarHBondContact O-N 2.96Å; L374-M377 PolarHBondContact O-N 3.49Å; M377-A380 WeakPolarHBondContact O-CB 3.3Å; M377-A380 PolarHBondContact O-N 2.9Å; M377-L381 WeakPolarHBondContact O-CG 3.36Å; M377-L381 PolarHBondContact O-N 3.15Å
378	L	85.3	Confident	87.1	Confident	36 Å²	36	12.7 Å²	12.7	19%	0.188	7%	0.068	C	C	.	.	H	α-helix	trans	-63.7	-41.5	171.2	-70	177	0	0	0	112.4	F24 F156 I157 L374 A375 A380 L381 M382	F24-L378 HydrophobicContact CZ-CB 3.9Å; F24-L378 HydrophobicContact CZ-CD1 4.48Å; F156-L378 HydrophobicContact CD1-CD2 4.44Å; I157-L378 HydrophobicContact CD1-CD2 4Å; I157-L378 HydrophobicContact CG1-CD2 3.6Å; L374-L378 VanDerWaalsContact O-CG 3.31Å; L374-L378 WeakPolarHBondContact O-CG 3.44Å; L374-L378 PolarHBondContact O-N 3.02Å; A375-L378 PolarHBondContact O-N 3.45Å; L378-A380 VanDerWaalsContact C-N 3.31Å; L378-A380 PolarHBondContact O-N 2.91Å; L378-L381 HydrophobicContact CD2-CD1 3.98Å; L378-L381 WeakPolarHBondContact O-CB 3.32Å; L378-L381 PolarHBondContact O-N 2.67Å; L378-M382 WeakPolarHBondContact O-CG 3.36Å; L378-M382 PolarHBondContact O-N 2.85Å; L378-M382 VanDerWaalsContact O-N 3.15Å
379	A	85.2	Confident	87.3	Confident	4 Å²	4	12 Å²	12	3%	0.033	6%	0.061	C	C	.	.	H	α-helix	trans	-65.5	-36.2	171.8	0	0	0	0	0	112.4	Y23 Q195 A375 V376 L381 M382 S383	Y23-A379 HydrophobicContact CE1-CB 3.44Å; Y23-A379 VanDerWaalsContact CE1-CB 3.44Å; Y23-A379 VanDerWaalsContact OH-CB 3.3Å; Y23-A379 WeakPolarHBondContact OH-CB 3.42Å; Q195-A379 PolarHBondContact OE1-O 2.98Å; Q195-A379 VanDerWaalsContact OE1-O 3.05Å; A375-A379 PolarHBondContact O-N 3.3Å; V376-A379 PolarHBondContact O-N 3.23Å; A379-L381 VanDerWaalsContact C-N 3.29Å; A379-L381 PolarHBondContact O-N 2.78Å; A379-M382 WeakPolarHBondContact O-CB 3.36Å; A379-M382 PolarHBondContact O-N 2.89Å; A379-M382 VanDerWaalsContact O-N 3.1Å; A379-S383 WeakPolarHBondContact O-CB 3.35Å; A379-S383 PolarHBondContact O-N 3.47Å
380	A	86.4	Confident	87.4	Confident	0 Å²	0	8.6 Å²	8.6	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-59.1	-43	175.9	0	0	0	0	0	112.7	Q195 I199 V376 M377 L378 S383 S384	Q195-A380 VanDerWaalsContact CD-CA 3.41Å; I199-A380 HydrophobicContact CD1-CB 3.72Å; V376-A380 WeakPolarHBondContact O-CB 3.46Å; V376-A380 PolarHBondContact O-N 3.5Å; M377-A380 WeakPolarHBondContact O-CB 3.3Å; M377-A380 PolarHBondContact O-N 2.9Å; L378-A380 VanDerWaalsContact C-N 3.31Å; L378-A380 PolarHBondContact O-N 2.91Å; A380-S383 PolarHBondContact O-N 2.9Å; A380-S384 PolarHBondContact O-N 3.33Å; A380-S384 PolarHBondContact O-OG 3.44Å; A380-S384 VanDerWaalsContact O-OG 3.11Å
381	L	85.4	Confident	87.4	Confident	1 Å²	1	6.8 Å²	6.8	1%	0.005	4%	0.036	C	C	.	.	H	α-helix	trans	-55.7	-50.5	170.5	-76.3	157.7	0	0	0	112.6	S69 D149 L172 M377 L378 A379 S383 S384 L385	S69-L381 WeakPolarHBondContact OG-CD2 3.25Å; D149-L381 WeakPolarHBondContact O-CD2 3.22Å; L172-L381 HydrophobicContact CD1-CB 3.96Å; L172-L381 HydrophobicContact CD1-CD1 4.07Å; L172-L381 HydrophobicContact CD1-CG 4.46Å; L172-L381 HydrophobicContact CD2-CD2 4.23Å; M377-L381 WeakPolarHBondContact O-CG 3.36Å; M377-L381 PolarHBondContact O-N 3.15Å; L378-L381 HydrophobicContact CD2-CD1 3.98Å; L378-L381 WeakPolarHBondContact O-CB 3.32Å; L378-L381 PolarHBondContact O-N 2.67Å; A379-L381 VanDerWaalsContact C-N 3.29Å; A379-L381 PolarHBondContact O-N 2.78Å; L381-S383 VanDerWaalsContact C-N 3.32Å; L381-S383 PolarHBondContact O-N 2.96Å; L381-S384 PolarHBondContact O-N 3.3Å; L381-L385 WeakPolarHBondContact O-CB 3.23Å; L381-L385 WeakPolarHBondContact O-CG 3.24Å; L381-L385 PolarHBondContact O-N 3.22Å
382	M	85.5	Confident	87.7	Confident	18 Å²	18	6.8 Å²	6.8	9%	0.089	4%	0.036	C	C	.	.	H	α-helix	trans	-60.3	-43.8	179.2	-60.4	-61.6	87.8	0	0	111.3	L172 I175 T176 L378 A379 A386	L172-M382 HydrophobicContact CB-CE 4.22Å; L172-M382 HydrophobicContact CD1-CE 3.04Å; L172-M382 HydrophobicContact CD2-CE 4.49Å; L172-M382 HydrophobicContact CG-CE 3.32Å; L172-M382 WeakPolarHBondContact O-CE 3.25Å; I175-M382 HydrophobicContact CB-SD 3.94Å; I175-M382 HydrophobicContact CG2-SD 3.67Å; T176-M382 WeakPolarHBondContact OG1-CE 3.23Å; T176-M382 PolarHBondContact OG1-SD 3.34Å; L378-M382 WeakPolarHBondContact O-CG 3.36Å; L378-M382 PolarHBondContact O-N 2.85Å; L378-M382 VanDerWaalsContact O-N 3.15Å; A379-M382 WeakPolarHBondContact O-CB 3.36Å; A379-M382 PolarHBondContact O-N 2.89Å; A379-M382 VanDerWaalsContact O-N 3.1Å; M382-A386 WeakPolarHBondContact O-CB 3.42Å; M382-A386 PolarHBondContact O-N 3.34Å
383	S	85.5	Confident	87.9	Confident	2 Å²	2	4.1 Å²	4.1	1%	0.014	2%	0.023	C	C	.	.	H	α-helix	trans	-64	-48.6	-179	157.4	0	0	0	0	111.7	D192 Q195 A379 A380 L381 A386 S387	D192-S383 WeakPolarHBondContact OD1-CB 3.42Å; D192-S383 PolarHBondContact OD1-OG 3.14Å; Q195-S383 VanDerWaalsContact OE1-CB 3.26Å; A379-S383 WeakPolarHBondContact O-CB 3.35Å; A379-S383 PolarHBondContact O-N 3.47Å; A380-S383 PolarHBondContact O-N 2.9Å; L381-S383 VanDerWaalsContact C-N 3.32Å; L381-S383 PolarHBondContact O-N 2.96Å; S383-A386 PolarHBondContact O-N 2.96Å; S383-S387 WeakPolarHBondContact O-CB 3.47Å; S383-S387 PolarHBondContact O-N 3.38Å; S383-S387 PolarHBondContact O-OG 2.95Å
384	S	88.1	Confident	87.9	Confident	4 Å²	4	4 Å²	4	3%	0.028	2%	0.022	C	C	.	.	H	α-helix	trans	-63.2	-46.9	179	-56.3	0	0	0	0	111.6	G68 D149 A380 L381 A386 S387 I388	G68-S384 WeakPolarHBondContact CA-OG 3.37Å; D149-S384 VanDerWaalsContact OD2-CB 3.26Å; D149-S384 WeakPolarHBondContact OD2-CB 3.3Å; A380-S384 PolarHBondContact O-N 3.33Å; A380-S384 PolarHBondContact O-OG 3.44Å; A380-S384 VanDerWaalsContact O-OG 3.11Å; L381-S384 PolarHBondContact O-N 3.3Å; S384-A386 PolarHBondContact O-N 2.6Å; S384-S387 VanDerWaalsContact O-CB 3.27Å; S384-S387 WeakPolarHBondContact O-CB 2.93Å; S384-S387 PolarHBondContact O-N 2.84Å; S384-I388 WeakPolarHBondContact O-CD1 3.45Å; S384-I388 WeakPolarHBondContact O-CG1 3.4Å; S384-I388 PolarHBondContact O-N 2.95Å; S384-I388 VanDerWaalsContact O-N 3.11Å
385	L	88.6	Confident	88.1	Confident	0 Å²	0	3.9 Å²	3.9	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-63.6	-43.7	176.8	-71.7	170.4	0	0	0	112.3	I146 D149 L172 L173 T176 L381 S387 I388 F389	I146-L385 HydrophobicContact CG2-CD2 4.09Å; D149-L385 HydrophobicContact CB-CD2 3.6Å; D149-L385 HydrophobicContact CB-CG 3.87Å; L172-L385 HydrophobicContact CD2-CD1 3.96Å; L172-L385 HydrophobicContact CG-CD1 4.21Å; L173-L385 HydrophobicContact CD2-CD1 4.3Å; T176-L385 HydrophobicContact CG2-CB 3.49Å; T176-L385 VanDerWaalsContact CG2-CB 3.49Å; L381-L385 WeakPolarHBondContact O-CB 3.23Å; L381-L385 WeakPolarHBondContact O-CG 3.24Å; L381-L385 PolarHBondContact O-N 3.22Å; L385-S387 PolarHBondContact O-N 2.93Å; L385-I388 PolarHBondContact O-N 3.48Å; L385-I388 VanDerWaalsContact O-N 3.15Å; L385-F389 HydrophobicContact CB-CE2 4.37Å; L385-F389 HydrophobicContact CB-CZ 4.46Å; L385-F389 WeakPolarHBondContact O-CB 3.37Å; L385-F389 VanDerWaalsContact O-CG 3.24Å; L385-F389 WeakPolarHBondContact O-CG 3.25Å; L385-F389 PolarHBondContact O-N 3.39Å
386	A	86.9	Confident	88.4	Confident	0 Å²	0	5.5 Å²	5.5	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-60.9	-35.1	177.3	0	0	0	0	0	112.2	T176 Y179 T180 L188 M382 S383 S384 F389 N390	T176-A386 HydrophobicContact CG2-CB 4.12Å; Y179-A386 HydrophobicContact CD1-CB 4.23Å; Y179-A386 HydrophobicContact CE1-CB 4.46Å; T180-A386 HydrophobicContact CG2-CB 4.36Å; T180-A386 VanDerWaalsContact OG1-CA 3.27Å; T180-A386 WeakPolarHBondContact OG1-CA 3.23Å; T180-A386 WeakPolarHBondContact OG1-CB 3.4Å; L188-A386 HydrophobicContact CD1-CB 4.4Å; L188-A386 HydrophobicContact CD2-CB 3.56Å; M382-A386 WeakPolarHBondContact O-CB 3.42Å; M382-A386 PolarHBondContact O-N 3.34Å; S383-A386 PolarHBondContact O-N 2.96Å; S384-A386 PolarHBondContact O-N 2.6Å; A386-F389 PolarHBondContact O-N 2.68Å; A386-N390 WeakPolarHBondContact O-CB 3.43Å; A386-N390 PolarHBondContact O-N 3.35Å
387	S	88.3	Confident	88.6	Confident	1 Å²	1	5.4 Å²	5.4	1%	0.007	3%	0.028	C	C	.	.	H	α-helix	trans	-63.9	-45.9	174.7	-58.1	0	0	0	0	112	R291 S383 S384 L385 N390 S391	R291-S387 PolarHBondContact NH2-OG 3.31Å; S383-S387 WeakPolarHBondContact O-CB 3.47Å; S383-S387 PolarHBondContact O-N 3.38Å; S383-S387 PolarHBondContact O-OG 2.95Å; S384-S387 VanDerWaalsContact O-CB 3.27Å; S384-S387 WeakPolarHBondContact O-CB 2.93Å; S384-S387 PolarHBondContact O-N 2.84Å; L385-S387 PolarHBondContact O-N 2.93Å; S387-N390 PolarHBondContact O-N 2.72Å; S387-S391 PolarHBondContact O-N 3.32Å; S387-S391 PolarHBondContact O-OG 3.38Å
388	I	90.6	Very high	88.6	Confident	5 Å²	5	6.7 Å²	6.7	3%	0.026	3%	0.034	C	C	.	.	H	α-helix	trans	-64.8	-43.7	177.9	-61.1	156	0	0	0	110.3	Y141 K145 I146 D149 S384 L385 S391 S392	Y141-I388 HydrophobicContact CD2-CG2 4.01Å; Y141-I388 HydrophobicContact CG-CG2 3.99Å; K145-I388 HydrophobicContact CB-CD1 3.54Å; K145-I388 HydrophobicContact CB-CG1 4.09Å; K145-I388 HydrophobicContact CD-CD1 4.28Å; K145-I388 HydrophobicContact CD-CG1 4.05Å; I146-I388 HydrophobicContact CD1-CG2 3.98Å; I146-I388 HydrophobicContact CG1-CB 4.44Å; I146-I388 HydrophobicContact CG1-CG2 3.59Å; D149-I388 WeakPolarHBondContact OD2-CD1 3.22Å; S384-I388 WeakPolarHBondContact O-CD1 3.45Å; S384-I388 WeakPolarHBondContact O-CG1 3.4Å; S384-I388 PolarHBondContact O-N 2.95Å; S384-I388 VanDerWaalsContact O-N 3.11Å; L385-I388 PolarHBondContact O-N 3.48Å; L385-I388 VanDerWaalsContact O-N 3.15Å; I388-S391 PolarHBondContact O-N 2.88Å; I388-S392 VanDerWaalsContact O-CB 3.27Å; I388-S392 WeakPolarHBondContact O-CB 3.21Å; I388-S392 PolarHBondContact O-N 3.33Å; I388-S392 PolarHBondContact O-OG 3.45Å
389	F	89.9	Confident	88.8	Confident	0 Å²	0	5.2 Å²	5.2	0%	0	3%	0.026	C	C	.	.	H	α-helix	trans	-63	-42.6	177.1	-67.5	-13.9	0	0	0	112.6	I146 L173 T176 T180 L385 A386 S392 S393 V421 I424 V425	I146-F389 HydrophobicContact CD1-CD1 4.36Å; I146-F389 HydrophobicContact CD1-CE1 3.97Å; I146-F389 HydrophobicContact CG1-CE1 4.2Å; I146-F389 HydrophobicContact CG2-CE1 4.33Å; L173-F389 HydrophobicContact CD2-CZ 3.97Å; T176-F389 HydrophobicContact CG2-CD2 3.89Å; T176-F389 HydrophobicContact CG2-CE2 3.65Å; T180-F389 HydrophobicContact CG2-CB 3.86Å; L385-F389 HydrophobicContact CB-CE2 4.37Å; L385-F389 HydrophobicContact CB-CZ 4.46Å; L385-F389 WeakPolarHBondContact O-CB 3.37Å; L385-F389 VanDerWaalsContact O-CG 3.24Å; L385-F389 WeakPolarHBondContact O-CG 3.25Å; L385-F389 PolarHBondContact O-N 3.39Å; A386-F389 PolarHBondContact O-N 2.68Å; F389-S392 PolarHBondContact O-OG 3.49Å; F389-S393 WeakPolarHBondContact O-CB 3.46Å; F389-S393 PolarHBondContact O-N 3.34Å; F389-V421 HydrophobicContact CB-CG1 3.96Å; F389-V421 HydrophobicContact CB-CG2 4.03Å; F389-V421 HydrophobicContact CD2-CG1 3.8Å; F389-V421 HydrophobicContact CE2-CG1 4.48Å; F389-V421 HydrophobicContact CG-CG1 3.9Å; F389-I424 HydrophobicContact CD1-CG2 3.93Å; F389-I424 HydrophobicContact CE1-CG2 4.08Å; F389-V425 HydrophobicContact CE1-CG2 4.05Å; F389-V425 HydrophobicContact CE2-CG2 3.75Å; F389-V425 HydrophobicContact CZ-CG2 3.46Å; F389-V425 VanDerWaalsContact CZ-CG2 3.46Å
390	N	88.1	Confident	89.1	Confident	2 Å²	2	6.2 Å²	6.2	1%	0.011	3%	0.031	C	C	.	.	H	α-helix	trans	-64.3	-44.5	176.3	178.3	74.5	0	0	0	111.6	L188 Q290 A386 S387 S393 T394	L188-N390 HydrophobicContact CD1-CB 4.12Å; Q290-N390 PolarHBondContact NE2-ND2 2.87Å; A386-N390 WeakPolarHBondContact O-CB 3.43Å; A386-N390 PolarHBondContact O-N 3.35Å; S387-N390 PolarHBondContact O-N 2.72Å; N390-S393 WeakPolarHBondContact O-CB 3.18Å; N390-S393 PolarHBondContact O-N 3.12Å; N390-T394 PolarHBondContact O-N 2.53Å; N390-T394 PolarHBondContact O-OG1 2.85Å
391	S	90.5	Very high	89.4	Confident	0 Å²	0	9.3 Å²	9.3	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-70.5	-36.9	178.7	-66.7	0	0	0	0	112.8	V287 Q290 S387 I388 T394 L395	V287-S391 WeakPolarHBondContact CA-OG 3.13Å; Q290-S391 PolarHBondContact OE1-OG 3.14Å; S387-S391 PolarHBondContact O-N 3.32Å; S387-S391 PolarHBondContact O-OG 3.38Å; I388-S391 PolarHBondContact O-N 2.88Å; S391-T394 PolarHBondContact O-N 3.37Å; S391-L395 WeakPolarHBondContact O-CG 3.26Å; S391-L395 PolarHBondContact O-N 3.38Å
392	S	92.4	Very high	89.5	Confident	0 Å²	0	11.5 Å²	11.5	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-64.7	-42.7	173.9	79.1	0	0	0	0	111.2	I388 F389 T394 L395 F396	I388-S392 VanDerWaalsContact O-CB 3.27Å; I388-S392 WeakPolarHBondContact O-CB 3.21Å; I388-S392 PolarHBondContact O-N 3.33Å; I388-S392 PolarHBondContact O-OG 3.45Å; F389-S392 PolarHBondContact O-OG 3.49Å; S392-T394 VanDerWaalsContact C-N 3.34Å; S392-T394 PolarHBondContact O-N 3.07Å; S392-L395 PolarHBondContact O-N 3.45Å; S392-F396 WeakPolarHBondContact O-CB 3.21Å; S392-F396 PolarHBondContact O-N 3.04Å
393	S	91.3	Very high	89.6	Confident	2 Å²	2	14.2 Å²	14.2	1%	0.014	7%	0.065	C	C	.	.	H	α-helix	trans	-59.8	-43.4	173.3	-173.1	0	0	0	0	111.7	F389 N390 F396 T397 G417	F389-S393 WeakPolarHBondContact O-CB 3.46Å; F389-S393 PolarHBondContact O-N 3.34Å; N390-S393 WeakPolarHBondContact O-CB 3.18Å; N390-S393 PolarHBondContact O-N 3.12Å; S393-F396 PolarHBondContact O-N 3.49Å; S393-T397 WeakPolarHBondContact O-CB 3.5Å; S393-T397 VanDerWaalsContact O-CG2 3.28Å; S393-T397 WeakPolarHBondContact O-CG2 3.5Å; S393-T397 PolarHBondContact O-N 3.47Å; S393-T397 PolarHBondContact O-OG1 3.03Å; S393-G417 WeakPolarHBondContact OG-CA 3.25Å; S393-G417 PolarHBondContact OG-O 3.25Å
394	T	88.9	Confident	89.9	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-61.7	-48.2	176	-50.5	0	0	0	0	111.1	F47 I114 T115 Q290 N390 S391 S392 T397 M398	F47-T394 HydrophobicContact CB-CG2 4.48Å; F47-T394 HydrophobicContact CD1-CG2 4.15Å; F47-T394 WeakPolarHBondContact CD1-OG1 3.47Å; F47-T394 WeakPolarHBondContact CE1-OG1 3.38Å; F47-T394 HydrophobicContact CG-CG2 4.29Å; I114-T394 HydrophobicContact CG2-CG2 4.4Å; T115-T394 HydrophobicContact CG2-CG2 3.97Å; Q290-T394 PolarHBondContact NE2-OG1 3.48Å; N390-T394 PolarHBondContact O-N 2.53Å; N390-T394 PolarHBondContact O-OG1 2.85Å; S391-T394 PolarHBondContact O-N 3.37Å; S392-T394 VanDerWaalsContact C-N 3.34Å; S392-T394 PolarHBondContact O-N 3.07Å; T394-T397 PolarHBondContact O-OG1 3.04Å; T394-M398 HydrophobicContact CG2-CG 4.17Å; T394-M398 VanDerWaalsContact O-CB 3.22Å; T394-M398 WeakPolarHBondContact O-CB 3.47Å; T394-M398 WeakPolarHBondContact O-CG 3.42Å; T394-M398 PolarHBondContact O-N 3.48Å
395	L	91.3	Very high	90.1	Very high	1 Å²	1	24.6 Å²	24.6	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-61.6	-47.1	178.8	-73.7	170.8	0	0	0	111.4	P117 L138 Y141 Q286 S391 S392 D399	P117-L395 HydrophobicContact CG-CD2 3.85Å; L138-L395 HydrophobicContact CD2-CB 4.25Å; Y141-L395 HydrophobicContact CE2-CD1 3.84Å; Q286-L395 HydrophobicContact CB-CD1 4.17Å; Q286-L395 HydrophobicContact CB-CD2 4.38Å; Q286-L395 HydrophobicContact CB-CG 4.33Å; Q286-L395 HydrophobicContact CG-CD1 4.46Å; Q286-L395 HydrophobicContact CG-CD2 4.24Å; Q286-L395 HydrophobicContact CG-CG 4.12Å; S391-L395 WeakPolarHBondContact O-CG 3.26Å; S391-L395 PolarHBondContact O-N 3.38Å; S392-L395 PolarHBondContact O-N 3.45Å; L395-D399 VanDerWaalsContact O-CB 3.26Å; L395-D399 WeakPolarHBondContact O-CB 3.19Å; L395-D399 PolarHBondContact O-N 3.01Å
396	F	94.1	Very high	89.9	Confident	34 Å²	34	29.9 Å²	29.9	15%	0.149	15%	0.145	C	C	.	.	I	π-helix	trans	-64.6	-49.9	-179.7	-176.6	-96.3	0	0	0	111.6	L138 S392 S393 I400 W401 V416 W420	L138-F396 HydrophobicContact CD1-CB 4.38Å; L138-F396 HydrophobicContact CD1-CD2 4.35Å; S392-F396 WeakPolarHBondContact O-CB 3.21Å; S392-F396 PolarHBondContact O-N 3.04Å; S393-F396 PolarHBondContact O-N 3.49Å; F396-I400 HydrophobicContact CD2-CB 4.25Å; F396-I400 HydrophobicContact CD2-CD1 3.92Å; F396-I400 HydrophobicContact CD2-CG2 4.42Å; F396-I400 HydrophobicContact CE2-CB 4.43Å; F396-I400 HydrophobicContact CE2-CD1 4.44Å; F396-I400 HydrophobicContact CE2-CG2 4.12Å; F396-I400 CarbonylContact O-C 3.53Å; F396-I400 WeakPolarHBondContact O-CA 3.41Å; F396-I400 VanDerWaalsContact O-CB 3.3Å; F396-I400 WeakPolarHBondContact O-CB 3.5Å; F396-I400 PolarHBondContact O-N 3.21Å; F396-W401 HydrophobicContact CE1-CE3 4.32Å; F396-W401 PolarHBondContact O-N 3.49Å; F396-V416 HydrophobicContact CD1-CG1 4.18Å; F396-V416 HydrophobicContact CE1-CG1 3.83Å; F396-W420 HydrophobicContact CB-CD2 3.8Å; F396-W420 HydrophobicContact CB-CE3 4.46Å; F396-W420 HydrophobicContact CB-CG 3.85Å; F396-W420 HydrophobicContact CB-CZ2 4.41Å; F396-W420 HydrophobicContact CD1-CB 4.03Å; F396-W420 AromaticContact CD1-CD2 3.82Å; F396-W420 HydrophobicContact CD1-CD2 3.82Å; F396-W420 AromaticContact CD1-CE3 3.84Å; F396-W420 HydrophobicContact CD1-CE3 3.84Å; F396-W420 AromaticContact CD1-CG 3.9Å; F396-W420 HydrophobicContact CD1-CG 3.9Å; F396-W420 AromaticContact CD2-CD2 3.67Å; F396-W420 HydrophobicContact CD2-CD2 3.67Å; F396-W420 AromaticContact CD2-CE2 3.85Å; F396-W420 AromaticContact CD2-CE3 3.47Å; F396-W420 HydrophobicContact CD2-CE3 3.47Å; F396-W420 VanDerWaalsContact CD2-CE3 3.47Å; F396-W420 HydrophobicContact CD2-CG 4.49Å; F396-W420 AromaticContact CD2-CH2 3.68Å; F396-W420 HydrophobicContact CD2-CH2 3.68Å; F396-W420 AromaticContact CD2-CZ2 3.87Å; F396-W420 HydrophobicContact CD2-CZ2 3.87Å; F396-W420 AromaticContact CD2-CZ3 3.48Å; F396-W420 HydrophobicContact CD2-CZ3 3.48Å; F396-W420 VanDerWaalsContact CD2-CZ3 3.48Å; F396-W420 HydrophobicContact CE1-CD2 4.33Å; F396-W420 AromaticContact CE1-CE3 3.88Å; F396-W420 HydrophobicContact CE1-CE3 3.88Å; F396-W420 HydrophobicContact CE2-CD2 4.21Å; F396-W420 AromaticContact CE2-CE3 3.53Å; F396-W420 HydrophobicContact CE2-CE3 3.53Å; F396-W420 AromaticContact CE2-CH2 3.92Å; F396-W420 HydrophobicContact CE2-CH2 3.92Å; F396-W420 AromaticContact CE2-CZ3 3.36Å; F396-W420 HydrophobicContact CE2-CZ3 3.36Å; F396-W420 HydrophobicContact CG-CB 4.44Å; F396-W420 AromaticContact CG-CD2 3.46Å; F396-W420 HydrophobicContact CG-CD2 3.46Å; F396-W420 VanDerWaalsContact CG-CD2 3.46Å; F396-W420 AromaticContact CG-CE2 3.83Å; F396-W420 AromaticContact CG-CE3 3.65Å; F396-W420 HydrophobicContact CG-CE3 3.65Å; F396-W420 AromaticContact CG-CG 3.82Å; F396-W420 HydrophobicContact CG-CG 3.82Å; F396-W420 HydrophobicContact CG-CH2 4.46Å; F396-W420 HydrophobicContact CG-CZ2 4.32Å; F396-W420 HydrophobicContact CG-CZ3 4.15Å; F396-W420 AromaticContact CZ-CE3 3.73Å; F396-W420 HydrophobicContact CZ-CE3 3.73Å; F396-W420 AromaticContact CZ-CZ3 3.92Å; F396-W420 HydrophobicContact CZ-CZ3 3.92Å
397	T	91.9	Very high	90	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	18%	0.183	C	C	.	.	I	π-helix	trans	-66.3	-49.4	-177.3	52.7	0	0	0	0	112	S393 T394 W401 T402 L413 V416	S393-T397 WeakPolarHBondContact O-CB 3.5Å; S393-T397 VanDerWaalsContact O-CG2 3.28Å; S393-T397 WeakPolarHBondContact O-CG2 3.5Å; S393-T397 PolarHBondContact O-N 3.47Å; S393-T397 PolarHBondContact O-OG1 3.03Å; T394-T397 PolarHBondContact O-OG1 3.04Å; T397-W401 WeakPolarHBondContact O-CB 3.03Å; T397-T402 WeakPolarHBondContact O-CG2 3.34Å; T397-T402 PolarHBondContact O-N 2.89Å; T397-L413 VanDerWaalsContact CG2-O 3.3Å; T397-L413 WeakPolarHBondContact CG2-O 3.15Å; T397-V416 HydrophobicContact CG2-CB 4.38Å; T397-V416 HydrophobicContact CG2-CG1 4.17Å
398	M	87.4	Confident	90	Very high	30 Å²	30	39 Å²	39	15%	0.148	19%	0.192	C	C	.	.	I	π-helix	trans	-81.9	-30.4	-171	-62.6	-62.7	-73.4	0	0	113.6	V43 I114 T115 T394 T402 L413	V43-M398 HydrophobicContact CG1-CE 4.07Å; V43-M398 HydrophobicContact CG1-SD 3.88Å; I114-M398 HydrophobicContact CD1-CE 4.14Å; T115-M398 HydrophobicContact CG2-CB 4.1Å; T394-M398 HydrophobicContact CG2-CG 4.17Å; T394-M398 VanDerWaalsContact O-CB 3.22Å; T394-M398 WeakPolarHBondContact O-CB 3.47Å; T394-M398 WeakPolarHBondContact O-CG 3.42Å; T394-M398 PolarHBondContact O-N 3.48Å; M398-T402 PolarHBondContact O-OG1 3.29Å; M398-L413 HydrophobicContact SD-CD1 4.38Å
399	D	87.9	Confident	90	Very high	5 Å²	5	42.5 Å²	42.5	3%	0.027	21%	0.214	C	C	.	.	I	π-helix	trans	-105.3	-24.7	-176.3	-66.4	-64.4	0	0	0	114.2	T115 Q118 S130 S134 L395 R403	T115-D399 VanDerWaalsContact CB-OD2 3.28Å; T115-D399 WeakPolarHBondContact CB-OD2 3.43Å; T115-D399 WeakPolarHBondContact CG2-OD2 3.45Å; T115-D399 PolarHBondContact OG1-OD1 2.81Å; T115-D399 VanDerWaalsContact OG1-OD1 3.13Å; T115-D399 PolarHBondContact OG1-OD2 2.85Å; Q118-D399 WeakPolarHBondContact CG-OD1 2.91Å; S130-D399 PolarHBondContact OG-OD1 3.45Å; S134-D399 WeakPolarHBondContact OG-CB 3.47Å; S134-D399 PolarHBondContact OG-OD2 2.87Å; L395-D399 VanDerWaalsContact O-CB 3.26Å; L395-D399 WeakPolarHBondContact O-CB 3.19Å; L395-D399 PolarHBondContact O-N 3.01Å; D399-R403 WeakPolarHBondContact O-CD 3.49Å; D399-R403 WeakPolarHBondContact O-CG 3.11Å; D399-R403 PolarHBondContact O-NE 2.87Å
400	I	91.6	Very high	89.8	Confident	25 Å²	25	46.8 Å²	46.8	13%	0.128	23%	0.234	C	C	.	.	I	π-helix	trans	-108.1	-55.5	-179	-56.5	177.3	0	0	0	110.4	L131 V135 L138 F396 T402 R403 I404	L131-I400 HydrophobicContact CD1-CG1 4.14Å; V135-I400 HydrophobicContact CG2-CD1 4.3Å; L138-I400 HydrophobicContact CD1-CD1 3.72Å; F396-I400 HydrophobicContact CD2-CB 4.25Å; F396-I400 HydrophobicContact CD2-CD1 3.92Å; F396-I400 HydrophobicContact CD2-CG2 4.42Å; F396-I400 HydrophobicContact CE2-CB 4.43Å; F396-I400 HydrophobicContact CE2-CD1 4.44Å; F396-I400 HydrophobicContact CE2-CG2 4.12Å; F396-I400 CarbonylContact O-C 3.53Å; F396-I400 WeakPolarHBondContact O-CA 3.41Å; F396-I400 VanDerWaalsContact O-CB 3.3Å; F396-I400 WeakPolarHBondContact O-CB 3.5Å; F396-I400 PolarHBondContact O-N 3.21Å; I400-T402 PolarHBondContact O-N 3.33Å; I400-R403 WeakPolarHBondContact O-CB 3.31Å; I400-R403 PolarHBondContact O-N 3.32Å; I400-I404 HydrophobicContact CG2-CD1 4.23Å; I400-I404 PolarHBondContact O-N 2.87Å
401	W	93.5	Very high	89.7	Confident	66 Å²	66	56.7 Å²	56.7	25%	0.25	27%	0.271	C	S	.	.	I	π-helix	trans	-64	-43.5	-174	-171.9	-100.7	0	0	0	113	F396 T397 R403 I404 R405 E412 V416	F396-W401 HydrophobicContact CE1-CE3 4.32Å; F396-W401 PolarHBondContact O-N 3.49Å; T397-W401 WeakPolarHBondContact O-CB 3.03Å; W401-R403 PolarHBondContact O-N 2.83Å; W401-I404 HydrophobicContact CE3-CD1 4.48Å; W401-I404 PolarHBondContact O-N 2.85Å; W401-R405 PolarHBondContact O-N 3.07Å; W401-E412 PolarHBondContact NE1-OE1 3.31Å; W401-V416 HydrophobicContact CB-CG1 4.37Å; W401-V416 HydrophobicContact CD2-CG1 3.79Å; W401-V416 HydrophobicContact CD2-CG2 4.14Å; W401-V416 HydrophobicContact CE3-CG1 4.03Å; W401-V416 HydrophobicContact CG-CG1 3.93Å; W401-V416 HydrophobicContact CH2-CG2 4.5Å; W401-V416 HydrophobicContact CZ2-CG2 3.88Å
402	T	88.2	Confident	89.7	Confident	46 Å²	46	58.5 Å²	58.5	28%	0.282	28%	0.28	S	S	.	.	H	α-helix	trans	-60.5	-17.8	175.8	57	0	0	0	0	113.7	T397 M398 I400 R405 P406 L413	T397-T402 WeakPolarHBondContact O-CG2 3.34Å; T397-T402 PolarHBondContact O-N 2.89Å; M398-T402 PolarHBondContact O-OG1 3.29Å; I400-T402 PolarHBondContact O-N 3.33Å; T402-R405 CarbonylContact O-C 3.56Å; T402-P406 VanDerWaalsContact O-CA 3.28Å; T402-P406 WeakPolarHBondContact O-CA 3.37Å; T402-L413 HydrophobicContact CG2-CD2 3.9Å
403	R	87.5	Confident	89.5	Confident	76 Å²	76	59.2 Å²	59.2	29%	0.287	28%	0.283	S	S	.	.	H	α-helix	trans	-81.9	-39.3	172.9	-58.1	-178.9	-176.8	-141.6	2.4	112	A127 S130 L131 D399 I400 W401	A127-R403 VanDerWaalsContact O-CZ 3.31Å; A127-R403 PolarHBondContact O-NH1 3.34Å; A127-R403 PolarHBondContact O-NH2 3.1Å; S130-R403 VanDerWaalsContact CB-NH2 3.26Å; S130-R403 PolarHBondContact OG-NH2 3.22Å; L131-R403 VanDerWaalsContact N-NH2 3.13Å; D399-R403 WeakPolarHBondContact O-CD 3.49Å; D399-R403 WeakPolarHBondContact O-CG 3.11Å; D399-R403 PolarHBondContact O-NE 2.87Å; I400-R403 WeakPolarHBondContact O-CB 3.31Å; I400-R403 PolarHBondContact O-N 3.32Å; W401-R403 PolarHBondContact O-N 2.83Å
404	I	90.9	Very high	89.2	Confident	119 Å²	119	60.1 Å²	60.1	61%	0.61	29%	0.288	S	S	*	.	H	α-helix	trans	-70.7	-39.4	177	-59.3	172.3	0	0	0	109.5	I400 W401	I400-I404 HydrophobicContact CG2-CD1 4.23Å; I400-I404 PolarHBondContact O-N 2.87Å; W401-I404 HydrophobicContact CE3-CD1 4.48Å; W401-I404 PolarHBondContact O-N 2.85Å
405	R	91.6	Very high	89.2	Confident	105 Å²	105	64.1 Å²	64.1	40%	0.396	31%	0.312	S	S	.	.			trans	-127.6	82.5	-177.3	-144.6	-85.7	174.3	155.9	-8.8	110.6	W401 T402 Q407 A408 E412	W401-R405 PolarHBondContact O-N 3.07Å; T402-R405 CarbonylContact O-C 3.56Å; R405-Q407 VanDerWaalsContact C-N 3.26Å; R405-Q407 PolarHBondContact NH1-O 3.33Å; R405-Q407 PolarHBondContact O-N 3.31Å; R405-A408 HydrophobicContact CB-CB 4.5Å; R405-A408 WeakPolarHBondContact O-CB 3.36Å; R405-A408 PolarHBondContact O-N 3.05Å; R405-A408 VanDerWaalsContact O-N 3.16Å; R405-E412 VanDerWaalsContact CD-OE1 3.32Å; R405-E412 WeakPolarHBondContact CD-OE1 3.39Å; R405-E412 IonicContact CZ-OE2 3.98Å; R405-E412 IonicContact NE-OE1 3.31Å; R405-E412 IonicContact NE-OE2 2.77Å; R405-E412 IonicContact NH1-OE1 2.64Å; R405-E412 IonicContact NH1-OE2 3.91Å; R405-E412 PolarHBondContact NH1-OE2 3.41Å
406	P	86.3	Confident	89.3	Confident	110 Å²	110	65.2 Å²	65.2	71%	0.714	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.1	-27.6	-174.4	-26.6	36	0	0	0	115.5	T402	T402-P406 VanDerWaalsContact O-CA 3.28Å; T402-P406 WeakPolarHBondContact O-CA 3.37Å
407	Q	88.3	Confident	89	Confident	169 Å²	169	63.7 Å²	63.7	79%	0.79	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.1	34.7	178.8	-63.3	-173.5	-11.1	0	0	112.2	R405 T409	R405-Q407 VanDerWaalsContact C-N 3.26Å; R405-Q407 PolarHBondContact NH1-O 3.33Å; R405-Q407 PolarHBondContact O-N 3.31Å; Q407-T409 PolarHBondContact O-N 3.4Å
408	A	88.1	Confident	88.8	Confident	23 Å²	23	68.3 Å²	68.3	19%	0.19	33%	0.33	C	S	.	.			trans	-62.4	133.8	177.7	0	0	0	0	0	111.5	R405 E412 L413	R405-A408 HydrophobicContact CB-CB 4.5Å; R405-A408 WeakPolarHBondContact O-CB 3.36Å; R405-A408 PolarHBondContact O-N 3.05Å; R405-A408 VanDerWaalsContact O-N 3.16Å; A408-E412 WeakPolarHBondContact CA-OE2 3Å; A408-L413 HydrophobicContact CB-CD2 3.93Å; A408-L413 HydrophobicContact CB-CG 4.04Å
409	T	89.9	Confident	89	Confident	80 Å²	80	70.6 Å²	70.6	49%	0.491	35%	0.345	S	S	.	.			trans	-79.7	157.6	174.9	64.3	0	0	0	0	110.5	Q407 R411 E412 L413	Q407-T409 PolarHBondContact O-N 3.4Å; T409-R411 PolarHBondContact O-N 2.97Å; T409-E412 PolarHBondContact N-OE2 3.24Å; T409-E412 WeakPolarHBondContact O-CB 3.12Å; T409-E412 PolarHBondContact O-N 3.09Å; T409-E412 VanDerWaalsContact O-N 3.12Å; T409-E412 WeakPolarHBondContact OG1-CB 3.01Å; T409-E412 PolarHBondContact OG1-N 3.47Å; T409-L413 PolarHBondContact O-N 3.4Å
410	E	85.8	Confident	89.2	Confident	89 Å²	89	72.6 Å²	72.6	42%	0.416	35%	0.352	S	S	.	.	H	α-helix	trans	-57.4	-38.8	177.8	-63.7	-162.7	125.4	0	0	112.4	V43 E412 L413 I414	V43-E410 HydrophobicContact CG2-CB 4.05Å; V43-E410 HydrophobicContact CG2-CG 3.94Å; V43-E410 PolarHBondContact N-OE1 3.17Å; E410-E412 PolarHBondContact O-N 2.65Å; E410-L413 PolarHBondContact O-N 3.49Å; E410-I414 WeakPolarHBondContact O-CG1 3.2Å; E410-I414 PolarHBondContact O-N 3.44Å; E410-I414 VanDerWaalsContact O-N 3.14Å
411	R	86.6	Confident	89.1	Confident	210 Å²	210	71.6 Å²	71.6	79%	0.792	35%	0.347	S	S	*	.	H	α-helix	trans	-63.3	-42.1	177.3	-67.7	-176	-177.8	175.1	1.1	112	T409 I414 V415	T409-R411 PolarHBondContact O-N 2.97Å; R411-I414 PolarHBondContact O-N 3.08Å; R411-V415 WeakPolarHBondContact O-CG2 3.35Å; R411-V415 PolarHBondContact O-N 2.9Å
412	E	91.3	Very high	88.8	Confident	39 Å²	39	73.4 Å²	73.4	18%	0.182	36%	0.362	C	S	.	.	H	α-helix	trans	-62.7	-45.9	177.2	-179.5	-169.3	160	0	0	111.4	W401 R405 A408 T409 E410 I414 V415 V416	W401-E412 PolarHBondContact NE1-OE1 3.31Å; R405-E412 VanDerWaalsContact CD-OE1 3.32Å; R405-E412 WeakPolarHBondContact CD-OE1 3.39Å; R405-E412 IonicContact CZ-OE2 3.98Å; R405-E412 IonicContact NE-OE1 3.31Å; R405-E412 IonicContact NE-OE2 2.77Å; R405-E412 IonicContact NH1-OE1 2.64Å; R405-E412 IonicContact NH1-OE2 3.91Å; R405-E412 PolarHBondContact NH1-OE2 3.41Å; A408-E412 WeakPolarHBondContact CA-OE2 3Å; T409-E412 PolarHBondContact N-OE2 3.24Å; T409-E412 WeakPolarHBondContact O-CB 3.12Å; T409-E412 PolarHBondContact O-N 3.09Å; T409-E412 VanDerWaalsContact O-N 3.12Å; T409-E412 WeakPolarHBondContact OG1-CB 3.01Å; T409-E412 PolarHBondContact OG1-N 3.47Å; E410-E412 PolarHBondContact O-N 2.65Å; E412-I414 VanDerWaalsContact C-N 3.27Å; E412-I414 PolarHBondContact O-N 3.42Å; E412-V415 PolarHBondContact O-N 3.15Å; E412-V415 VanDerWaalsContact O-N 3.14Å; E412-V416 HydrophobicContact CG-CG2 4.2Å; E412-V416 WeakPolarHBondContact O-CB 3.3Å; E412-V416 VanDerWaalsContact O-CG2 3.31Å; E412-V416 WeakPolarHBondContact O-CG2 3.37Å; E412-V416 PolarHBondContact O-N 3.08Å
413	L	87.4	Confident	88.9	Confident	15 Å²	15	74 Å²	74	8%	0.079	37%	0.367	C	S	.	.	H	α-helix	trans	-58.6	-40.9	178	-68.7	171.3	0	0	0	111.6	V43 T397 M398 T402 A408 T409 E410 G417	V43-L413 HydrophobicContact CG2-CD1 4.08Å; T397-L413 VanDerWaalsContact CG2-O 3.3Å; T397-L413 WeakPolarHBondContact CG2-O 3.15Å; M398-L413 HydrophobicContact SD-CD1 4.38Å; T402-L413 HydrophobicContact CG2-CD2 3.9Å; A408-L413 HydrophobicContact CB-CD2 3.93Å; A408-L413 HydrophobicContact CB-CG 4.04Å; T409-L413 PolarHBondContact O-N 3.4Å; E410-L413 PolarHBondContact O-N 3.49Å; L413-G417 PolarHBondContact O-N 3.39Å
414	I	85.1	Confident	89	Confident	20 Å²	20	70.3 Å²	70.3	10%	0.103	35%	0.353	C	S	.	.	H	α-helix	trans	-65.7	-43.4	176.6	-64.3	165	0	0	0	111.2	E410 R411 E412 G417 R418	E410-I414 WeakPolarHBondContact O-CG1 3.2Å; E410-I414 PolarHBondContact O-N 3.44Å; E410-I414 VanDerWaalsContact O-N 3.14Å; R411-I414 PolarHBondContact O-N 3.08Å; E412-I414 VanDerWaalsContact C-N 3.27Å; E412-I414 PolarHBondContact O-N 3.42Å; I414-G417 PolarHBondContact O-N 3.49Å; I414-R418 WeakPolarHBondContact O-CG 3.38Å; I414-R418 PolarHBondContact O-N 2.87Å; I414-R418 VanDerWaalsContact O-N 3.13Å
415	V	89.5	Confident	88.8	Confident	85 Å²	85	65.3 Å²	65.3	52%	0.515	33%	0.328	S	S	.	.	H	α-helix	trans	-66.2	-48.9	179.6	171.9	0	0	0	0	111.3	R411 E412 G417 R418 V419	R411-V415 WeakPolarHBondContact O-CG2 3.35Å; R411-V415 PolarHBondContact O-N 2.9Å; E412-V415 PolarHBondContact O-N 3.15Å; E412-V415 VanDerWaalsContact O-N 3.14Å; V415-G417 PolarHBondContact O-N 3.49Å; V415-R418 WeakPolarHBondContact O-CB 3.26Å; V415-R418 PolarHBondContact O-N 3.24Å; V415-R418 VanDerWaalsContact O-N 3.08Å; V415-V419 WeakPolarHBondContact O-CG2 3.1Å; V415-V419 PolarHBondContact O-N 3.33Å
416	V	92.3	Very high	88.6	Confident	24 Å²	24	62.8 Å²	62.8	15%	0.145	33%	0.33	C	S	.	.	H	α-helix	trans	-58.8	-40.7	177	172.1	0	0	0	0	110.4	F396 T397 W401 E412 R418 V419 W420	F396-V416 HydrophobicContact CD1-CG1 4.18Å; F396-V416 HydrophobicContact CE1-CG1 3.83Å; T397-V416 HydrophobicContact CG2-CB 4.38Å; T397-V416 HydrophobicContact CG2-CG1 4.17Å; W401-V416 HydrophobicContact CB-CG1 4.37Å; W401-V416 HydrophobicContact CD2-CG1 3.79Å; W401-V416 HydrophobicContact CD2-CG2 4.14Å; W401-V416 HydrophobicContact CE3-CG1 4.03Å; W401-V416 HydrophobicContact CG-CG1 3.93Å; W401-V416 HydrophobicContact CH2-CG2 4.5Å; W401-V416 HydrophobicContact CZ2-CG2 3.88Å; E412-V416 HydrophobicContact CG-CG2 4.2Å; E412-V416 WeakPolarHBondContact O-CB 3.3Å; E412-V416 VanDerWaalsContact O-CG2 3.31Å; E412-V416 WeakPolarHBondContact O-CG2 3.37Å; E412-V416 PolarHBondContact O-N 3.08Å; V416-R418 VanDerWaalsContact C-N 3.31Å; V416-R418 PolarHBondContact O-N 3.16Å; V416-V419 PolarHBondContact O-N 3.38Å; V416-W420 WeakPolarHBondContact O-CB 3.48Å; V416-W420 PolarHBondContact O-N 2.98Å
417	G	88.5	Confident	88.8	Confident	1 Å²	1	61.3 Å²	61.3	1%	0.01	32%	0.315	C	S	.	.	H	α-helix	trans	-57.9	-41.2	175.4	0	0	0	0	0	113.5	S393 L413 I414 V415 V421	S393-G417 WeakPolarHBondContact OG-CA 3.25Å; S393-G417 PolarHBondContact OG-O 3.25Å; L413-G417 PolarHBondContact O-N 3.39Å; I414-G417 PolarHBondContact O-N 3.49Å; V415-G417 PolarHBondContact O-N 3.49Å; G417-V421 WeakPolarHBondContact O-CG2 3.29Å; G417-V421 PolarHBondContact O-N 3.1Å
418	R	87.3	Confident	88.7	Confident	97 Å²	97	53.2 Å²	53.2	37%	0.366	28%	0.277	S	S	.	.	H	α-helix	trans	-69.9	-40.7	176.9	-68.5	168.8	170.2	-171.3	-0.3	112.5	V181 I414 V415 V416 W420 V421 L422	V181-R418 HydrophobicContact CG1-CB 4.37Å; V181-R418 HydrophobicContact CG1-CG 3.94Å; V181-R418 HydrophobicContact CG2-CB 4.36Å; V181-R418 HydrophobicContact CG2-CG 4.36Å; V181-R418 PolarHBondContact O-NE 3.16Å; V181-R418 PolarHBondContact O-NH2 2.82Å; V181-R418 VanDerWaalsContact O-NH2 3.17Å; I414-R418 WeakPolarHBondContact O-CG 3.38Å; I414-R418 PolarHBondContact O-N 2.87Å; I414-R418 VanDerWaalsContact O-N 3.13Å; V415-R418 WeakPolarHBondContact O-CB 3.26Å; V415-R418 PolarHBondContact O-N 3.24Å; V415-R418 VanDerWaalsContact O-N 3.08Å; V416-R418 VanDerWaalsContact C-N 3.31Å; V416-R418 PolarHBondContact O-N 3.16Å; R418-W420 VanDerWaalsContact C-N 3.31Å; R418-W420 PolarHBondContact O-N 3.46Å; R418-V421 PolarHBondContact O-N 3.3Å; R418-L422 PolarHBondContact O-N 3.33Å
419	V	90.9	Very high	88.5	Confident	79 Å²	79	54.8 Å²	54.8	48%	0.479	28%	0.281	S	S	.	.	H	α-helix	trans	-62.8	-41.1	175.8	175	0	0	0	0	110.6	V415 V416 V421 L422 C423	V415-V419 WeakPolarHBondContact O-CG2 3.1Å; V415-V419 PolarHBondContact O-N 3.33Å; V416-V419 PolarHBondContact O-N 3.38Å; V419-V421 VanDerWaalsContact C-N 3.27Å; V419-V421 PolarHBondContact O-N 3.12Å; V419-L422 WeakPolarHBondContact O-CB 2.88Å; V419-L422 PolarHBondContact O-N 2.99Å; V419-C423 PolarHBondContact O-N 2.92Å; V419-C423 VanDerWaalsContact O-N 3.09Å; V419-C423 PolarHBondContact O-SG 3.08Å
420	W	92.6	Very high	88.3	Confident	46 Å²	46	55.8 Å²	55.8	17%	0.174	29%	0.291	C	S	.	.	H	α-helix	trans	-58.4	-37.8	176.3	-179.9	-103.5	0	0	0	113.1	L138 F396 V416 R418 L422 C423 I424	L138-W420 HydrophobicContact CD1-CZ2 3.88Å; L138-W420 HydrophobicContact CD2-CZ2 4.05Å; L138-W420 HydrophobicContact CG-CZ2 4.43Å; F396-W420 HydrophobicContact CB-CD2 3.8Å; F396-W420 HydrophobicContact CB-CE3 4.46Å; F396-W420 HydrophobicContact CB-CG 3.85Å; F396-W420 HydrophobicContact CB-CZ2 4.41Å; F396-W420 HydrophobicContact CD1-CB 4.03Å; F396-W420 AromaticContact CD1-CD2 3.82Å; F396-W420 HydrophobicContact CD1-CD2 3.82Å; F396-W420 AromaticContact CD1-CE3 3.84Å; F396-W420 HydrophobicContact CD1-CE3 3.84Å; F396-W420 AromaticContact CD1-CG 3.9Å; F396-W420 HydrophobicContact CD1-CG 3.9Å; F396-W420 AromaticContact CD2-CD2 3.67Å; F396-W420 HydrophobicContact CD2-CD2 3.67Å; F396-W420 AromaticContact CD2-CE2 3.85Å; F396-W420 AromaticContact CD2-CE3 3.47Å; F396-W420 HydrophobicContact CD2-CE3 3.47Å; F396-W420 VanDerWaalsContact CD2-CE3 3.47Å; F396-W420 HydrophobicContact CD2-CG 4.49Å; F396-W420 AromaticContact CD2-CH2 3.68Å; F396-W420 HydrophobicContact CD2-CH2 3.68Å; F396-W420 AromaticContact CD2-CZ2 3.87Å; F396-W420 HydrophobicContact CD2-CZ2 3.87Å; F396-W420 AromaticContact CD2-CZ3 3.48Å; F396-W420 HydrophobicContact CD2-CZ3 3.48Å; F396-W420 VanDerWaalsContact CD2-CZ3 3.48Å; F396-W420 HydrophobicContact CE1-CD2 4.33Å; F396-W420 AromaticContact CE1-CE3 3.88Å; F396-W420 HydrophobicContact CE1-CE3 3.88Å; F396-W420 HydrophobicContact CE2-CD2 4.21Å; F396-W420 AromaticContact CE2-CE3 3.53Å; F396-W420 HydrophobicContact CE2-CE3 3.53Å; F396-W420 AromaticContact CE2-CH2 3.92Å; F396-W420 HydrophobicContact CE2-CH2 3.92Å; F396-W420 AromaticContact CE2-CZ3 3.36Å; F396-W420 HydrophobicContact CE2-CZ3 3.36Å; F396-W420 HydrophobicContact CG-CB 4.44Å; F396-W420 AromaticContact CG-CD2 3.46Å; F396-W420 HydrophobicContact CG-CD2 3.46Å; F396-W420 VanDerWaalsContact CG-CD2 3.46Å; F396-W420 AromaticContact CG-CE2 3.83Å; F396-W420 AromaticContact CG-CE3 3.65Å; F396-W420 HydrophobicContact CG-CE3 3.65Å; F396-W420 AromaticContact CG-CG 3.82Å; F396-W420 HydrophobicContact CG-CG 3.82Å; F396-W420 HydrophobicContact CG-CH2 4.46Å; F396-W420 HydrophobicContact CG-CZ2 4.32Å; F396-W420 HydrophobicContact CG-CZ3 4.15Å; F396-W420 AromaticContact CZ-CE3 3.73Å; F396-W420 HydrophobicContact CZ-CE3 3.73Å; F396-W420 AromaticContact CZ-CZ3 3.92Å; F396-W420 HydrophobicContact CZ-CZ3 3.92Å; V416-W420 WeakPolarHBondContact O-CB 3.48Å; V416-W420 PolarHBondContact O-N 2.98Å; R418-W420 VanDerWaalsContact C-N 3.31Å; R418-W420 PolarHBondContact O-N 3.46Å; W420-L422 VanDerWaalsContact C-N 3.3Å; W420-L422 PolarHBondContact O-N 2.96Å; W420-C423 WeakPolarHBondContact O-CB 3.48Å; W420-C423 PolarHBondContact O-N 3.01Å; W420-I424 PolarHBondContact O-N 3.14Å
421	V	88.9	Confident	88.2	Confident	4 Å²	4	54.6 Å²	54.6	2%	0.024	28%	0.282	C	S	.	.	H	α-helix	trans	-61.7	-39.4	175.5	174.6	0	0	0	0	111.2	F389 G417 R418 V419 I424 V425	F389-V421 HydrophobicContact CB-CG1 3.96Å; F389-V421 HydrophobicContact CB-CG2 4.03Å; F389-V421 HydrophobicContact CD2-CG1 3.8Å; F389-V421 HydrophobicContact CE2-CG1 4.48Å; F389-V421 HydrophobicContact CG-CG1 3.9Å; G417-V421 WeakPolarHBondContact O-CG2 3.29Å; G417-V421 PolarHBondContact O-N 3.1Å; R418-V421 PolarHBondContact O-N 3.3Å; V419-V421 VanDerWaalsContact C-N 3.27Å; V419-V421 PolarHBondContact O-N 3.12Å; V421-I424 WeakPolarHBondContact O-CG2 3.42Å; V421-V425 WeakPolarHBondContact O-CB 3.44Å; V421-V425 WeakPolarHBondContact O-CG2 3.49Å; V421-V425 PolarHBondContact O-N 3.34Å; V421-V425 VanDerWaalsContact O-N 3.11Å
422	L	88.5	Confident	87.9	Confident	105 Å²	105	45 Å²	45	55%	0.55	25%	0.247	S	C	.	.	H	α-helix	trans	-66.4	-40.1	175.6	-60.1	178.4	0	0	0	111.6	R418 V419 W420 V425 A426	R418-L422 PolarHBondContact O-N 3.33Å; V419-L422 WeakPolarHBondContact O-CB 2.88Å; V419-L422 PolarHBondContact O-N 2.99Å; W420-L422 VanDerWaalsContact C-N 3.3Å; W420-L422 PolarHBondContact O-N 2.96Å; L422-V425 PolarHBondContact O-N 3.22Å; L422-A426 PolarHBondContact O-N 2.79Å; L422-A426 VanDerWaalsContact O-N 3.13Å
423	C	90.8	Very high	87.4	Confident	57 Å²	57	46.3 Å²	46.3	39%	0.385	26%	0.259	S	S	.	.	H	α-helix	trans	-62.7	-47.7	176.7	-63.2	0	0	0	0	112.3	V419 W420 V425 A426 I427	V419-C423 PolarHBondContact O-N 2.92Å; V419-C423 VanDerWaalsContact O-N 3.09Å; V419-C423 PolarHBondContact O-SG 3.08Å; W420-C423 WeakPolarHBondContact O-CB 3.48Å; W420-C423 PolarHBondContact O-N 3.01Å; C423-V425 VanDerWaalsContact C-N 3.3Å; C423-V425 PolarHBondContact O-N 3.36Å; C423-A426 PolarHBondContact O-N 3.24Å; C423-I427 WeakPolarHBondContact O-CG1 3.49Å; C423-I427 PolarHBondContact O-N 3.36Å; C423-I427 VanDerWaalsContact O-N 3.08Å
424	I	89.1	Confident	87	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-67.6	-33.2	-178.3	-156.5	171.8	0	0	0	111.7	I142 I146 F389 W420 V421 I427 S428	I142-I424 HydrophobicContact CD1-CD1 4.42Å; I142-I424 HydrophobicContact CD1-CG1 4.1Å; I142-I424 HydrophobicContact CG1-CD1 3.93Å; I142-I424 HydrophobicContact CG1-CG1 3.74Å; I146-I424 HydrophobicContact CD1-CD1 3.64Å; I146-I424 HydrophobicContact CD1-CG1 3.83Å; F389-I424 HydrophobicContact CD1-CG2 3.93Å; F389-I424 HydrophobicContact CE1-CG2 4.08Å; W420-I424 PolarHBondContact O-N 3.14Å; V421-I424 WeakPolarHBondContact O-CG2 3.42Å; I424-I427 PolarHBondContact O-N 3.14Å; I424-S428 WeakPolarHBondContact O-CB 3.48Å; I424-S428 PolarHBondContact O-N 2.8Å; I424-S428 PolarHBondContact O-OG 3.48Å
425	V	86.3	Confident	86.6	Confident	13 Å²	13	48 Å²	48	8%	0.079	27%	0.268	C	S	.	.	H	α-helix	trans	-61	-48.4	172.5	164.5	0	0	0	0	110.7	L173 F389 V421 L422 C423 I427 S428 I429	L173-V425 HydrophobicContact CB-CG1 4.08Å; L173-V425 HydrophobicContact CD1-CG1 4.21Å; F389-V425 HydrophobicContact CE1-CG2 4.05Å; F389-V425 HydrophobicContact CE2-CG2 3.75Å; F389-V425 HydrophobicContact CZ-CG2 3.46Å; F389-V425 VanDerWaalsContact CZ-CG2 3.46Å; V421-V425 WeakPolarHBondContact O-CB 3.44Å; V421-V425 WeakPolarHBondContact O-CG2 3.49Å; V421-V425 PolarHBondContact O-N 3.34Å; V421-V425 VanDerWaalsContact O-N 3.11Å; L422-V425 PolarHBondContact O-N 3.22Å; C423-V425 VanDerWaalsContact C-N 3.3Å; C423-V425 PolarHBondContact O-N 3.36Å; V425-I427 PolarHBondContact O-N 3.15Å; V425-S428 PolarHBondContact O-N 2.83Å; V425-I429 HydrophobicContact CG1-CD1 4.19Å; V425-I429 WeakPolarHBondContact O-CG1 3.24Å; V425-I429 PolarHBondContact O-N 3.28Å
426	A	88.3	Confident	85.9	Confident	53 Å²	53	46.8 Å²	46.8	44%	0.438	26%	0.256	S	S	.	.	H	α-helix	trans	-60.4	-45.7	178.6	0	0	0	0	0	112.2	L422 C423 S428 I429 C430	L422-A426 PolarHBondContact O-N 2.79Å; L422-A426 VanDerWaalsContact O-N 3.13Å; C423-A426 PolarHBondContact O-N 3.24Å; A426-S428 VanDerWaalsContact C-N 3.3Å; A426-S428 PolarHBondContact O-N 3.22Å; A426-I429 PolarHBondContact O-N 3.35Å; A426-C430 PolarHBondContact O-N 3.43Å; A426-C430 PolarHBondContact O-SG 2.69Å
427	I	89.5	Confident	84.9	Confident	78 Å²	78	50 Å²	50	40%	0.4	29%	0.285	S	S	.	.	H	α-helix	trans	-61.7	-40.5	177.3	-65	166.1	0	0	0	111	I142 C423 I424 V425 I429 C430 W431	I142-I427 HydrophobicContact CD1-CG2 4.09Å; I142-I427 HydrophobicContact CG2-CG2 4.12Å; C423-I427 WeakPolarHBondContact O-CG1 3.49Å; C423-I427 PolarHBondContact O-N 3.36Å; C423-I427 VanDerWaalsContact O-N 3.08Å; I424-I427 PolarHBondContact O-N 3.14Å; V425-I427 PolarHBondContact O-N 3.15Å; I427-I429 VanDerWaalsContact C-N 3.34Å; I427-I429 PolarHBondContact O-N 2.9Å; I427-C430 PolarHBondContact O-N 3.13Å; I427-W431 PolarHBondContact O-N 3.49Å; I427-W431 VanDerWaalsContact O-N 3.16Å
428	S	85.2	Confident	83.8	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-65.3	-37.7	179.8	-56.8	0	0	0	0	111.9	I146 M150 I424 V425 A426 W431 I432	I146-S428 VanDerWaalsContact CG2-OG 3.3Å; I146-S428 WeakPolarHBondContact CG2-OG 3.49Å; M150-S428 WeakPolarHBondContact CE-O 3.3Å; I424-S428 WeakPolarHBondContact O-CB 3.48Å; I424-S428 PolarHBondContact O-N 2.8Å; I424-S428 PolarHBondContact O-OG 3.48Å; V425-S428 PolarHBondContact O-N 2.83Å; A426-S428 VanDerWaalsContact C-N 3.3Å; A426-S428 PolarHBondContact O-N 3.22Å; S428-W431 WeakPolarHBondContact O-CB 3.41Å; S428-W431 PolarHBondContact O-N 3.49Å; S428-W431 VanDerWaalsContact O-N 3.14Å; S428-I432 PolarHBondContact O-N 3Å
429	I	83.9	Confident	82.8	Confident	55 Å²	55	46.2 Å²	46.2	28%	0.282	27%	0.273	S	S	.	.	H	α-helix	trans	-62.6	-44.2	174.2	-66.9	168.2	0	0	0	110.8	I170 L173 V425 A426 I427 W431 I432	I170-I429 HydrophobicContact CG1-CD1 4.48Å; L173-I429 HydrophobicContact CD1-CD1 3.85Å; L173-I429 HydrophobicContact CD1-CG1 3.4Å; L173-I429 VanDerWaalsContact CD1-CG1 3.4Å; V425-I429 HydrophobicContact CG1-CD1 4.19Å; V425-I429 WeakPolarHBondContact O-CG1 3.24Å; V425-I429 PolarHBondContact O-N 3.28Å; A426-I429 PolarHBondContact O-N 3.35Å; I427-I429 VanDerWaalsContact C-N 3.34Å; I427-I429 PolarHBondContact O-N 2.9Å; I429-W431 PolarHBondContact O-N 2.87Å; I429-I432 HydrophobicContact CB-CD1 4.44Å; I429-I432 HydrophobicContact CG2-CD1 4.19Å; I429-I432 WeakPolarHBondContact O-CD1 3.47Å; I429-I432 VanDerWaalsContact O-CG1 3.31Å; I429-I432 WeakPolarHBondContact O-CG1 3.36Å; I429-I432 PolarHBondContact O-N 3.44Å
430	C	86.3	Confident	81.5	Confident	102 Å²	102	44 Å²	44	69%	0.689	26%	0.261	S	S	*	.	H	α-helix	trans	-62.1	-23.3	176.4	-65.6	0	0	0	0	113.1	A426 I427 P433	A426-C430 PolarHBondContact O-N 3.43Å; A426-C430 PolarHBondContact O-SG 2.69Å; I427-C430 PolarHBondContact O-N 3.13Å; C430-P433 WeakPolarHBondContact O-CD 3.23Å
431	W	83.2	Confident	80.3	Confident	63 Å²	63	42 Å²	42	24%	0.239	26%	0.255	C	S	.	.	H	α-helix	trans	-84.8	-14.6	-178.4	-161.8	-102.1	0	0	0	114.1	F143 S147 I427 S428 I429 P433 I434 V435	F143-W431 AromaticContact CD1-CD2 3.95Å; F143-W431 HydrophobicContact CD1-CD2 3.95Å; F143-W431 AromaticContact CD1-CE2 3.4Å; F143-W431 HydrophobicContact CD1-CE3 4.39Å; F143-W431 AromaticContact CD1-CH2 3.91Å; F143-W431 HydrophobicContact CD1-CH2 3.91Å; F143-W431 AromaticContact CD1-CZ2 3.39Å; F143-W431 HydrophobicContact CD1-CZ2 3.39Å; F143-W431 HydrophobicContact CD1-CZ3 4.38Å; F143-W431 AromaticContact CD1-NE1 3.73Å; F143-W431 AromaticContact CE1-CD2 3.88Å; F143-W431 HydrophobicContact CE1-CD2 3.88Å; F143-W431 AromaticContact CE1-CE2 3.63Å; F143-W431 AromaticContact CE1-CE3 3.84Å; F143-W431 HydrophobicContact CE1-CE3 3.84Å; F143-W431 AromaticContact CE1-CH2 3.37Å; F143-W431 HydrophobicContact CE1-CH2 3.37Å; F143-W431 AromaticContact CE1-CZ2 3.38Å; F143-W431 HydrophobicContact CE1-CZ2 3.38Å; F143-W431 AromaticContact CE1-CZ3 3.6Å; F143-W431 HydrophobicContact CE1-CZ3 3.6Å; F143-W431 HydrophobicContact CG-CZ2 4.44Å; F143-W431 HydrophobicContact CZ-CH2 4.15Å; F143-W431 HydrophobicContact CZ-CZ2 4.41Å; F143-W431 HydrophobicContact CZ-CZ3 4.43Å; S147-W431 VanDerWaalsContact OG-CD1 3.26Å; I427-W431 PolarHBondContact O-N 3.49Å; I427-W431 VanDerWaalsContact O-N 3.16Å; S428-W431 WeakPolarHBondContact O-CB 3.41Å; S428-W431 PolarHBondContact O-N 3.49Å; S428-W431 VanDerWaalsContact O-N 3.14Å; I429-W431 PolarHBondContact O-N 2.87Å; W431-P433 VanDerWaalsContact C-CD 3.44Å; W431-I434 HydrophobicContact CD2-CB 4.28Å; W431-I434 HydrophobicContact CD2-CD1 3.87Å; W431-I434 HydrophobicContact CE3-CD1 3.44Å; W431-I434 VanDerWaalsContact CE3-CD1 3.44Å; W431-I434 HydrophobicContact CH2-CD1 3.72Å; W431-I434 HydrophobicContact CH2-CG2 4.16Å; W431-I434 HydrophobicContact CZ2-CB 4.29Å; W431-I434 HydrophobicContact CZ2-CD1 4.13Å; W431-I434 HydrophobicContact CZ2-CG2 3.64Å; W431-I434 HydrophobicContact CZ3-CD1 3.36Å; W431-I434 WeakPolarHBondContact O-CB 3.23Å; W431-I434 PolarHBondContact O-N 2.84Å; W431-I434 VanDerWaalsContact O-N 3.07Å; W431-V435 VanDerWaalsContact CD1-CG2 3.42Å; W431-V435 HydrophobicContact CG-CG2 4.5Å; W431-V435 PolarHBondContact O-N 3.31Å
432	I	80.1	Confident	79.7	Confident	8 Å²	8	44.1 Å²	44.1	4%	0.041	27%	0.265	C	S	.	.	H	α-helix	trans	-49.5	-48	-177.8	-63.6	164.7	0	0	0	113.4	M150 Y166 V169 S428 I429 I434 V435 Q436	M150-I432 HydrophobicContact CE-CD1 4.2Å; M150-I432 HydrophobicContact CE-CG1 3.38Å; M150-I432 HydrophobicContact SD-CD1 3.96Å; M150-I432 HydrophobicContact SD-CG1 3.82Å; Y166-I432 HydrophobicContact CD1-CD1 4.39Å; Y166-I432 HydrophobicContact CE1-CB 4.48Å; Y166-I432 HydrophobicContact CE1-CG2 3.92Å; V169-I432 HydrophobicContact CB-CD1 4.26Å; V169-I432 HydrophobicContact CG1-CD1 3.58Å; V169-I432 HydrophobicContact CG2-CD1 4.34Å; S428-I432 PolarHBondContact O-N 3Å; I429-I432 HydrophobicContact CB-CD1 4.44Å; I429-I432 HydrophobicContact CG2-CD1 4.19Å; I429-I432 WeakPolarHBondContact O-CD1 3.47Å; I429-I432 VanDerWaalsContact O-CG1 3.31Å; I429-I432 WeakPolarHBondContact O-CG1 3.36Å; I429-I432 PolarHBondContact O-N 3.44Å; I432-I434 PolarHBondContact O-N 3.01Å; I432-V435 PolarHBondContact O-N 3.34Å; I432-V435 VanDerWaalsContact O-N 3.16Å; I432-Q436 HydrophobicContact CG2-CG 4.34Å; I432-Q436 PolarHBondContact O-N 3.48Å
433	P	80.8	Confident	79.2	Confident	67 Å²	67	39.1 Å²	39.1	44%	0.435	24%	0.239	S	C	.	.	H	α-helix	trans	-62.1	-32.7	-176.3	-22.9	35.6	0	0	0	112.7	C430 W431 Q436 A437	C430-P433 WeakPolarHBondContact O-CD 3.23Å; W431-P433 VanDerWaalsContact C-CD 3.44Å; P433-Q436 PolarHBondContact O-N 3.28Å; P433-A437 PolarHBondContact O-N 3.02Å
434	I	79.5	Confident	78.8	Confident	69 Å²	69	36.6 Å²	36.6	35%	0.354	22%	0.221	S	C	.	.	H	α-helix	trans	-70.5	-42	179.6	-63.1	167.5	0	0	0	110.1	W431 I432 Q436 A437 A438	W431-I434 HydrophobicContact CD2-CB 4.28Å; W431-I434 HydrophobicContact CD2-CD1 3.87Å; W431-I434 HydrophobicContact CE3-CD1 3.44Å; W431-I434 VanDerWaalsContact CE3-CD1 3.44Å; W431-I434 HydrophobicContact CH2-CD1 3.72Å; W431-I434 HydrophobicContact CH2-CG2 4.16Å; W431-I434 HydrophobicContact CZ2-CB 4.29Å; W431-I434 HydrophobicContact CZ2-CD1 4.13Å; W431-I434 HydrophobicContact CZ2-CG2 3.64Å; W431-I434 HydrophobicContact CZ3-CD1 3.36Å; W431-I434 WeakPolarHBondContact O-CB 3.23Å; W431-I434 PolarHBondContact O-N 2.84Å; W431-I434 VanDerWaalsContact O-N 3.07Å; I432-I434 PolarHBondContact O-N 3.01Å; I434-Q436 VanDerWaalsContact C-N 3.3Å; I434-Q436 PolarHBondContact O-N 3.34Å; I434-A437 PolarHBondContact O-N 3.33Å; I434-A438 VanDerWaalsContact O-CB 3.25Å; I434-A438 WeakPolarHBondContact O-CB 3.28Å; I434-A438 PolarHBondContact O-N 3.16Å
435	V	76.4	Confident	78.6	Confident	2 Å²	2	38 Å²	38	1%	0.012	23%	0.229	C	C	.	.	H	α-helix	trans	-61.4	-42.2	175.2	-178.4	0	0	0	0	110.5	F151 W431 I432 A437 A438 Q439	F151-V435 HydrophobicContact CB-CG1 4.5Å; W431-V435 VanDerWaalsContact CD1-CG2 3.42Å; W431-V435 HydrophobicContact CG-CG2 4.5Å; W431-V435 PolarHBondContact O-N 3.31Å; I432-V435 PolarHBondContact O-N 3.34Å; I432-V435 VanDerWaalsContact O-N 3.16Å; V435-A437 VanDerWaalsContact C-N 3.32Å; V435-A437 PolarHBondContact O-N 3.49Å; V435-A438 PolarHBondContact O-N 3.37Å; V435-Q439 VanDerWaalsContact O-CG 3.29Å; V435-Q439 WeakPolarHBondContact O-CG 3.4Å; V435-Q439 PolarHBondContact O-N 2.82Å; V435-Q439 VanDerWaalsContact O-N 3.17Å
436	Q	75.6	Confident	78.5	Confident	60 Å²	60	37.7 Å²	37.7	28%	0.28	23%	0.226	S	C	.	.	H	α-helix	trans	-63.4	-37	178	-71.2	-174.4	-51.8	0	0	113.2	F151 Y166 I432 P433 I434	F151-Q436 HydrophobicContact CE2-CG 4.45Å; Y166-Q436 PolarHBondContact OH-OE1 2.85Å; I432-Q436 HydrophobicContact CG2-CG 4.34Å; I432-Q436 PolarHBondContact O-N 3.48Å; P433-Q436 PolarHBondContact O-N 3.28Å; I434-Q436 VanDerWaalsContact C-N 3.3Å; I434-Q436 PolarHBondContact O-N 3.34Å
437	A	71.6	Confident	78.3	Confident	90 Å²	90	36.3 Å²	36.3	74%	0.744	21%	0.211	S	C	*	.	H	α-helix	trans	-77	-32.2	177.5	0	0	0	0	0	113.3	P433 I434 V435	P433-A437 PolarHBondContact O-N 3.02Å; I434-A437 PolarHBondContact O-N 3.33Å; V435-A437 VanDerWaalsContact C-N 3.32Å; V435-A437 PolarHBondContact O-N 3.49Å
438	A	66.1	Low	78.3	Confident	13 Å²	13	34.5 Å²	34.5	11%	0.107	20%	0.201	C	C	.	.	H	α-helix	trans	-87.6	-19.9	-172.6	0	0	0	0	0	114.5	I434 V435 S440 Y446 F495	I434-A438 VanDerWaalsContact O-CB 3.25Å; I434-A438 WeakPolarHBondContact O-CB 3.28Å; I434-A438 PolarHBondContact O-N 3.16Å; V435-A438 PolarHBondContact O-N 3.37Å; A438-S440 PolarHBondContact O-N 3.17Å; A438-Y446 HydrophobicContact CB-CD2 4.23Å; A438-Y446 HydrophobicContact CB-CE2 3.67Å; A438-F495 HydrophobicContact CB-CD1 4.08Å; A438-F495 HydrophobicContact CB-CE1 3.64Å
439	Q	66.3	Low	78.4	Confident	6 Å²	6	35 Å²	35	3%	0.028	20%	0.204	C	C	.	.			trans	-79.5	119.3	179.8	64.7	-172.7	-30.1	0	0	111.2	V435 G441	V435-Q439 VanDerWaalsContact O-CG 3.29Å; V435-Q439 WeakPolarHBondContact O-CG 3.4Å; V435-Q439 PolarHBondContact O-N 2.82Å; V435-Q439 VanDerWaalsContact O-N 3.17Å; Q439-G441 PolarHBondContact O-N 2.83Å; Q439-G441 VanDerWaalsContact O-N 3.1Å
440	S	62.1	Low	78.7	Confident	32 Å²	32	32.5 Å²	32.5	22%	0.224	19%	0.192	C	C	.	.			trans	-81.4	28.4	179.6	53.2	0	0	0	0	113.8	A438 G500	A438-S440 PolarHBondContact O-N 3.17Å; S440-G500 VanDerWaalsContact CB-O 3.25Å; S440-G500 WeakPolarHBondContact CB-O 3.25Å
441	G	67.4	Low	78.9	Confident	5 Å²	5	28 Å²	28	5%	0.052	16%	0.162	C	C	.	.	S	Bend	trans	89.8	-7.8	-178.4	0	0	0	0	0	115.1	S353 N354 Q439	S353-G441 PolarHBondContact OG-O 3.41Å; N354-G441 PolarHBondContact ND2-O 3.28Å; Q439-G441 PolarHBondContact O-N 2.83Å; Q439-G441 VanDerWaalsContact O-N 3.1Å
442	Q	77.6	Confident	79.3	Confident	49 Å²	49	25.2 Å²	25.2	23%	0.229	15%	0.152	C	C	.	.			trans	-123.7	101.8	173.9	-63.9	178.7	-87.6	0	0	109.7	A81 F444 D445 Y446	A81-Q442 HydrophobicContact CB-CG 4.47Å; Q442-F444 VanDerWaalsContact C-N 3.28Å; Q442-F444 PolarHBondContact O-N 3.46Å; Q442-D445 HydrophobicContact CB-CB 4.31Å; Q442-D445 WeakPolarHBondContact CB-OD2 3.14Å; Q442-D445 VanDerWaalsContact CD-OD2 3.25Å; Q442-D445 PolarHBondContact NE2-OD2 2.97Å; Q442-D445 VanDerWaalsContact NE2-OD2 3.14Å; Q442-D445 PolarHBondContact O-N 3.39Å; Q442-Y446 PolarHBondContact O-N 3.2Å
443	L	78.5	Confident	79.8	Confident	0 Å²	0	24.9 Å²	24.9	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-64	-37.9	-174.7	-178.4	67	0	0	0	111	V148 F151 N354 D445 Y446 I447	V148-L443 HydrophobicContact CG1-CD2 3.87Å; V148-L443 HydrophobicContact CG1-CG 4.3Å; V148-L443 HydrophobicContact CG2-CD1 4.27Å; F151-L443 HydrophobicContact CD1-CD1 3.87Å; F151-L443 HydrophobicContact CD1-CD2 3.78Å; F151-L443 HydrophobicContact CD1-CG 4.34Å; F151-L443 HydrophobicContact CE1-CD1 4.48Å; F151-L443 HydrophobicContact CE1-CD2 4.45Å; N354-L443 PolarHBondContact OD1-N 2.64Å; L443-D445 PolarHBondContact O-N 3.06Å; L443-Y446 WeakPolarHBondContact O-CB 3.45Å; L443-Y446 PolarHBondContact O-N 2.91Å; L443-I447 HydrophobicContact CG-CD1 4.34Å; L443-I447 VanDerWaalsContact O-CG1 3.25Å; L443-I447 WeakPolarHBondContact O-CG1 3.45Å; L443-I447 PolarHBondContact O-N 3.31Å
444	F	81.9	Confident	80.3	Confident	4 Å²	4	22.5 Å²	22.5	2%	0.018	13%	0.133	C	C	.	.	H	α-helix	trans	-63.7	-41.5	-176.6	-161.8	-99.5	0	0	0	112.5	L75 V86 F89 Q442 Y446 I447 Q448	L75-F444 HydrophobicContact CB-CD2 4.39Å; L75-F444 HydrophobicContact CB-CE2 4.38Å; L75-F444 HydrophobicContact CD1-CE1 4.19Å; L75-F444 HydrophobicContact CD1-CE2 4.18Å; L75-F444 HydrophobicContact CD1-CZ 3.93Å; V86-F444 HydrophobicContact CG2-CD1 3.8Å; V86-F444 HydrophobicContact CG2-CE1 3.85Å; F89-F444 HydrophobicContact CB-CE1 4.32Å; F89-F444 HydrophobicContact CB-CZ 4.24Å; F89-F444 HydrophobicContact CD1-CE1 4.22Å; F89-F444 HydrophobicContact CD1-CZ 4.49Å; F89-F444 AromaticContact CD2-CE1 3.69Å; F89-F444 HydrophobicContact CD2-CE1 3.69Å; F89-F444 HydrophobicContact CD2-CZ 4.43Å; F89-F444 HydrophobicContact CE1-CE1 4.49Å; F89-F444 AromaticContact CE2-CE1 3.98Å; F89-F444 HydrophobicContact CE2-CE1 3.98Å; F89-F444 AromaticContact CG-CE1 3.81Å; F89-F444 HydrophobicContact CG-CE1 3.81Å; F89-F444 HydrophobicContact CG-CZ 4.14Å; F89-F444 HydrophobicContact CZ-CE1 4.39Å; Q442-F444 VanDerWaalsContact C-N 3.28Å; Q442-F444 PolarHBondContact O-N 3.46Å; F444-Y446 PolarHBondContact O-N 3.43Å; F444-I447 WeakPolarHBondContact O-CB 3.08Å; F444-I447 PolarHBondContact O-N 3.01Å; F444-Q448 HydrophobicContact CD1-CG 3.87Å; F444-Q448 HydrophobicContact CE1-CG 3.7Å; F444-Q448 HydrophobicContact CZ-CG 4.28Å; F444-Q448 WeakPolarHBondContact O-CG 3.27Å; F444-Q448 PolarHBondContact O-N 2.68Å
445	D	83.7	Confident	80.9	Confident	28 Å²	28	19.2 Å²	19.2	15%	0.15	12%	0.117	C	C	.	.	H	α-helix	trans	-68.3	-35.2	-179.5	-63.9	-45.6	0	0	0	112.4	Q442 L443 I447 Q448 S449	Q442-D445 HydrophobicContact CB-CB 4.31Å; Q442-D445 WeakPolarHBondContact CB-OD2 3.14Å; Q442-D445 VanDerWaalsContact CD-OD2 3.25Å; Q442-D445 PolarHBondContact NE2-OD2 2.97Å; Q442-D445 VanDerWaalsContact NE2-OD2 3.14Å; Q442-D445 PolarHBondContact O-N 3.39Å; L443-D445 PolarHBondContact O-N 3.06Å; D445-I447 VanDerWaalsContact C-N 3.31Å; D445-I447 PolarHBondContact O-N 2.81Å; D445-Q448 PolarHBondContact O-N 3.2Å; D445-S449 WeakPolarHBondContact O-CB 3.4Å; D445-S449 PolarHBondContact O-N 3.29Å; D445-S449 PolarHBondContact O-OG 3.45Å
446	Y	83.8	Confident	81.9	Confident	7 Å²	7	19.1 Å²	19.1	3%	0.027	12%	0.116	C	C	.	.	H	α-helix	trans	-57.2	-44	170.7	168.6	-99.1	0	0	0	111.9	A438 Q442 L443 F444 S449 V450 F495	A438-Y446 HydrophobicContact CB-CD2 4.23Å; A438-Y446 HydrophobicContact CB-CE2 3.67Å; Q442-Y446 PolarHBondContact O-N 3.2Å; L443-Y446 WeakPolarHBondContact O-CB 3.45Å; L443-Y446 PolarHBondContact O-N 2.91Å; F444-Y446 PolarHBondContact O-N 3.43Å; Y446-S449 WeakPolarHBondContact CA-OG 3.09Å; Y446-S449 PolarHBondContact O-OG 2.7Å; Y446-V450 HydrophobicContact CD2-CG2 4.36Å; Y446-V450 HydrophobicContact CE2-CG2 3.95Å; Y446-V450 WeakPolarHBondContact O-CG2 3.4Å; Y446-V450 PolarHBondContact O-N 3.06Å; Y446-V450 VanDerWaalsContact O-N 3.15Å; Y446-F495 AromaticContact CE2-CE1 3.77Å; Y446-F495 HydrophobicContact CE2-CE1 3.77Å; Y446-F495 AromaticContact CE2-CZ 3.63Å; Y446-F495 HydrophobicContact CE2-CZ 3.63Å
447	I	85.3	Confident	82.8	Confident	24 Å²	24	16.4 Å²	16.4	12%	0.123	10%	0.104	C	C	.	.	H	α-helix	trans	-67.3	-46.8	-178.7	-56.4	166.6	0	0	0	110.7	V148 L443 F444 D445 S449 S451	V148-I447 HydrophobicContact CB-CD1 3.8Å; V148-I447 HydrophobicContact CB-CG1 4.3Å; V148-I447 HydrophobicContact CG1-CD1 3.29Å; V148-I447 HydrophobicContact CG1-CG1 4.3Å; V148-I447 HydrophobicContact CG2-CB 4.45Å; V148-I447 HydrophobicContact CG2-CD1 3.17Å; V148-I447 HydrophobicContact CG2-CG1 3.16Å; L443-I447 HydrophobicContact CG-CD1 4.34Å; L443-I447 VanDerWaalsContact O-CG1 3.25Å; L443-I447 WeakPolarHBondContact O-CG1 3.45Å; L443-I447 PolarHBondContact O-N 3.31Å; F444-I447 WeakPolarHBondContact O-CB 3.08Å; F444-I447 PolarHBondContact O-N 3.01Å; D445-I447 VanDerWaalsContact C-N 3.31Å; D445-I447 PolarHBondContact O-N 2.81Å; I447-S449 VanDerWaalsContact C-N 3.32Å; I447-S451 WeakPolarHBondContact O-CB 3.3Å; I447-S451 PolarHBondContact O-N 3.44Å; I447-S451 PolarHBondContact O-OG 2.87Å
448	Q	88.8	Confident	83.9	Confident	40 Å²	40	12.4 Å²	12.4	19%	0.187	7%	0.07	C	C	.	.	H	α-helix	trans	-70	-33.7	-174.3	-62.3	-58.9	-6.8	0	0	111	F89 F444 D445 S452 Y517	F89-Q448 HydrophobicContact CD1-CG 4.31Å; F89-Q448 HydrophobicContact CE1-CB 4.14Å; F89-Q448 VanDerWaalsContact CE1-CD 3.5Å; F89-Q448 HydrophobicContact CE1-CG 3.63Å; F89-Q448 HydrophobicContact CZ-CB 4.09Å; F89-Q448 HydrophobicContact CZ-CG 3.78Å; F444-Q448 HydrophobicContact CD1-CG 3.87Å; F444-Q448 HydrophobicContact CE1-CG 3.7Å; F444-Q448 HydrophobicContact CZ-CG 4.28Å; F444-Q448 WeakPolarHBondContact O-CG 3.27Å; F444-Q448 PolarHBondContact O-N 2.68Å; D445-Q448 PolarHBondContact O-N 3.2Å; Q448-S452 WeakPolarHBondContact O-CB 3.48Å; Q448-S452 PolarHBondContact O-N 3.42Å; Q448-S452 PolarHBondContact O-OG 3.31Å; Q448-Y517 HydrophobicContact CB-CE2 3.81Å
449	S	88.6	Confident	85.3	Confident	10 Å²	10	11.8 Å²	11.8	7%	0.07	7%	0.065	C	C	.	.	H	α-helix	trans	-65.7	-54.1	172.9	54.4	0	0	0	0	112	D445 Y446 I447 S451 S452 Y453	D445-S449 WeakPolarHBondContact O-CB 3.4Å; D445-S449 PolarHBondContact O-N 3.29Å; D445-S449 PolarHBondContact O-OG 3.45Å; Y446-S449 WeakPolarHBondContact CA-OG 3.09Å; Y446-S449 PolarHBondContact O-OG 2.7Å; I447-S449 VanDerWaalsContact C-N 3.32Å; S449-S451 VanDerWaalsContact C-N 3.3Å; S449-S451 PolarHBondContact O-N 3.14Å; S449-S452 WeakPolarHBondContact O-CA 3.3Å; S449-S452 WeakPolarHBondContact O-CB 3.41Å; S449-S452 PolarHBondContact O-N 3.48Å; S449-Y453 WeakPolarHBondContact O-CD2 3.35Å; S449-Y453 WeakPolarHBondContact O-CE2 3.3Å; S449-Y453 VanDerWaalsContact O-CG 3.23Å; S449-Y453 PolarHBondContact O-N 3.39Å
450	V	89.2	Confident	86.8	Confident	4 Å²	4	11.5 Å²	11.5	2%	0.024	6%	0.063	C	C	.	.	H	α-helix	trans	-57.7	-43.6	177.3	177.5	0	0	0	0	111.4	T144 Y446 S452 Y453 L454 M491 F495	T144-V450 HydrophobicContact CG2-CB 4.15Å; T144-V450 HydrophobicContact CG2-CG1 3.58Å; Y446-V450 HydrophobicContact CD2-CG2 4.36Å; Y446-V450 HydrophobicContact CE2-CG2 3.95Å; Y446-V450 WeakPolarHBondContact O-CG2 3.4Å; Y446-V450 PolarHBondContact O-N 3.06Å; Y446-V450 VanDerWaalsContact O-N 3.15Å; V450-S452 VanDerWaalsContact C-N 3.32Å; V450-S452 PolarHBondContact O-N 3.36Å; V450-Y453 PolarHBondContact O-N 3.27Å; V450-L454 HydrophobicContact CG1-CD1 4.16Å; V450-L454 PolarHBondContact O-N 3.49Å; V450-M491 HydrophobicContact CG1-SD 4.41Å; V450-F495 HydrophobicContact CG2-CE2 4Å; V450-F495 HydrophobicContact CG2-CZ 3.74Å
451	S	89.7	Confident	88.3	Confident	7 Å²	7	10 Å²	10	5%	0.049	5%	0.053	C	C	.	.	H	α-helix	trans	-62.2	-41.5	175.8	-58.5	0	0	0	0	111.1	I447 S449 Y453 L454 S455	I447-S451 WeakPolarHBondContact O-CB 3.3Å; I447-S451 PolarHBondContact O-N 3.44Å; I447-S451 PolarHBondContact O-OG 2.87Å; S449-S451 VanDerWaalsContact C-N 3.3Å; S449-S451 PolarHBondContact O-N 3.14Å; S451-Y453 VanDerWaalsContact C-N 3.25Å; S451-Y453 PolarHBondContact O-N 2.91Å; S451-L454 PolarHBondContact O-N 3.28Å; S451-S455 WeakPolarHBondContact O-CB 3.42Å; S451-S455 PolarHBondContact O-N 3.03Å; S451-S455 PolarHBondContact O-OG 3.13Å
452	S	92	Very high	89.6	Confident	5 Å²	5	9.9 Å²	9.9	4%	0.035	5%	0.051	C	C	.	.	H	α-helix	trans	-66.9	-22.6	178.6	-68.1	0	0	0	0	113.8	Q448 S449 V450 P456 Y517	Q448-S452 WeakPolarHBondContact O-CB 3.48Å; Q448-S452 PolarHBondContact O-N 3.42Å; Q448-S452 PolarHBondContact O-OG 3.31Å; S449-S452 WeakPolarHBondContact O-CA 3.3Å; S449-S452 WeakPolarHBondContact O-CB 3.41Å; S449-S452 PolarHBondContact O-N 3.48Å; V450-S452 VanDerWaalsContact C-N 3.32Å; V450-S452 PolarHBondContact O-N 3.36Å; S452-P456 WeakPolarHBondContact O-CD 3.23Å; S452-P456 WeakPolarHBondContact O-CG 3.47Å; S452-Y517 WeakPolarHBondContact OG-CD2 3.45Å
453	Y	91.6	Very high	90.3	Very high	1 Å²	1	9.4 Å²	9.4	0%	0.004	5%	0.05	C	C	.	.	H	α-helix	trans	-84	-25.1	176.5	-55	-34.9	0	0	0	113.6	S449 V450 S451 G487 R490 M491 E494 Y517 F520 L524	S449-Y453 WeakPolarHBondContact O-CD2 3.35Å; S449-Y453 WeakPolarHBondContact O-CE2 3.3Å; S449-Y453 VanDerWaalsContact O-CG 3.23Å; S449-Y453 PolarHBondContact O-N 3.39Å; V450-Y453 PolarHBondContact O-N 3.27Å; S451-Y453 VanDerWaalsContact C-N 3.25Å; S451-Y453 PolarHBondContact O-N 2.91Å; Y453-G487 VanDerWaalsContact O-CA 3.23Å; Y453-G487 WeakPolarHBondContact O-CA 3.25Å; Y453-R490 HydrophobicContact CD1-CG 3.91Å; Y453-R490 HydrophobicContact CE1-CG 3.68Å; Y453-R490 PolarHBondContact OH-NH1 3.41Å; Y453-R490 PolarHBondContact OH-NH2 3.03Å; Y453-M491 HydrophobicContact CD2-CB 3.91Å; Y453-M491 HydrophobicContact CD2-CG 3.92Å; Y453-M491 HydrophobicContact CG-CB 4.34Å; Y453-E494 WeakPolarHBondContact CE2-OE2 3.33Å; Y453-E494 PolarHBondContact OH-OE1 2.97Å; Y453-E494 PolarHBondContact OH-OE2 3.02Å; Y453-Y517 WeakPolarHBondContact OH-CB 3.48Å; Y453-F520 AromaticContact CD1-CD1 3.63Å; Y453-F520 HydrophobicContact CD1-CD1 3.63Å; Y453-F520 AromaticContact CD1-CE1 3.95Å; Y453-F520 HydrophobicContact CD1-CE1 3.95Å; Y453-F520 HydrophobicContact CE1-CD1 4.03Å; Y453-L524 WeakPolarHBondContact O-CD2 3.23Å
454	L	91.6	Very high	90.9	Very high	16 Å²	16	10.2 Å²	10.2	8%	0.084	5%	0.054	C	C	.	.	H	α-helix	trans	-116.8	-28.1	-169.9	-62.7	177.2	0	0	0	113.8	L140 V450 S451 L484 L488 M491	L140-L454 HydrophobicContact CD2-CB 3.66Å; L140-L454 HydrophobicContact CD2-CD1 3.45Å; L140-L454 VanDerWaalsContact CD2-CD1 3.45Å; L140-L454 HydrophobicContact CD2-CG 4.21Å; V450-L454 HydrophobicContact CG1-CD1 4.16Å; V450-L454 PolarHBondContact O-N 3.49Å; S451-L454 PolarHBondContact O-N 3.28Å; L454-L484 HydrophobicContact CD2-CD1 3.63Å; L454-L488 HydrophobicContact CD2-CD2 4.14Å; L454-M491 HydrophobicContact CD1-SD 3.97Å; L454-M491 HydrophobicContact CD2-SD 4.31Å; L454-M491 HydrophobicContact CG-SD 4.17Å
455	S	92.3	Very high	91.3	Very high	1 Å²	1	10 Å²	10	1%	0.007	5%	0.053	C	C	.	.	S	Bend	trans	-78.5	-35.1	-177.4	69.1	0	0	0	0	116.3	S451 P457 I458 A459	S451-S455 WeakPolarHBondContact O-CB 3.42Å; S451-S455 PolarHBondContact O-N 3.03Å; S451-S455 PolarHBondContact O-OG 3.13Å; S455-P457 VanDerWaalsContact C-CD 3.5Å; S455-I458 WeakPolarHBondContact O-CB 3.49Å; S455-I458 PolarHBondContact O-N 3.38Å; S455-A459 PolarHBondContact O-N 3.04Å
456	P	95.5	Very high	91.3	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-59.3	-37.3	-173.6	-25.9	36.1	0	0	0	115.4	I276 S452 I458 A459 S460 A521 L524 F525	I276-P456 HydrophobicContact CG2-CB 3.85Å; I276-P456 HydrophobicContact CG2-CG 4.2Å; S452-P456 WeakPolarHBondContact O-CD 3.23Å; S452-P456 WeakPolarHBondContact O-CG 3.47Å; P456-I458 VanDerWaalsContact C-N 3.27Å; P456-I458 PolarHBondContact O-N 3.08Å; P456-A459 PolarHBondContact O-N 3.33Å; P456-S460 WeakPolarHBondContact O-CB 3.27Å; P456-S460 PolarHBondContact O-N 3.43Å; P456-A521 HydrophobicContact CG-CB 3.88Å; P456-L524 HydrophobicContact CB-CB 4.25Å; P456-L524 HydrophobicContact CB-CD2 4.13Å; P456-L524 HydrophobicContact CB-CG 4.13Å; P456-L524 HydrophobicContact CG-CD2 4.03Å; P456-L524 HydrophobicContact CG-CG 4.49Å; P456-F525 HydrophobicContact CB-CB 4.03Å
457	P	95.9	Very high	91.4	Very high	3 Å²	3	12.9 Å²	12.9	2%	0.019	7%	0.065	C	C	.	.	H	α-helix	trans	-59.5	-38.3	174	-26.9	36.9	0	0	0	113	S455 S460 V461 L480 L524 T528	S455-P457 VanDerWaalsContact C-CD 3.5Å; P457-S460 WeakPolarHBondContact O-CB 3.42Å; P457-V461 PolarHBondContact O-N 3.4Å; P457-V461 VanDerWaalsContact O-N 3.16Å; P457-L480 HydrophobicContact CB-CD2 4.17Å; P457-L480 WeakPolarHBondContact O-CD2 3.43Å; P457-L524 HydrophobicContact CG-CD1 4.26Å; P457-L524 HydrophobicContact CG-CD2 4Å; P457-L524 HydrophobicContact CG-CG 4Å; P457-T528 HydrophobicContact CB-CG2 4.01Å
458	I	94.9	Very high	91.4	Very high	6 Å²	6	13.5 Å²	13.5	3%	0.031	7%	0.07	C	C	.	.	H	α-helix	trans	-69.2	-48.1	178	-55.9	174.3	0	0	0	109.6	L133 I136 L140 S455 P456 S460 V461 F462 L480	L133-I458 HydrophobicContact CD2-CD1 4.26Å; L133-I458 HydrophobicContact CD2-CG1 3.97Å; L133-I458 HydrophobicContact CD2-CG2 4.08Å; I136-I458 HydrophobicContact CG2-CD1 4.07Å; L140-I458 HydrophobicContact CD1-CD1 4.1Å; S455-I458 WeakPolarHBondContact O-CB 3.49Å; S455-I458 PolarHBondContact O-N 3.38Å; P456-I458 VanDerWaalsContact C-N 3.27Å; P456-I458 PolarHBondContact O-N 3.08Å; I458-S460 VanDerWaalsContact C-N 3.26Å; I458-S460 PolarHBondContact O-N 3.03Å; I458-V461 PolarHBondContact O-N 3.48Å; I458-F462 HydrophobicContact CG2-CD2 3.75Å; I458-F462 HydrophobicContact CG2-CE2 3.83Å; I458-F462 WeakPolarHBondContact O-CD2 3.38Å; I458-F462 PolarHBondContact O-N 2.84Å; I458-L480 HydrophobicContact CG1-CD2 4.31Å
459	A	95.5	Very high	91	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-54.2	-44.8	175.9	0	0	0	0	0	111.7	I276 I279 W280 S455 P456 F462 L463 F525	I276-A459 HydrophobicContact CG2-CB 4.24Å; I279-A459 HydrophobicContact CB-CB 4.47Å; I279-A459 HydrophobicContact CG2-CB 4.16Å; W280-A459 HydrophobicContact CB-CB 4.05Å; S455-A459 PolarHBondContact O-N 3.04Å; P456-A459 PolarHBondContact O-N 3.33Å; A459-F462 PolarHBondContact O-N 3.35Å; A459-L463 VanDerWaalsContact O-CB 3.31Å; A459-L463 WeakPolarHBondContact O-CB 3.25Å; A459-L463 PolarHBondContact O-N 3.07Å; A459-F525 HydrophobicContact CB-CD2 4.31Å; A459-F525 HydrophobicContact CB-CE2 4.25Å
460	S	96.4	Very high	90.8	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-57.1	-52.9	177.9	176	0	0	0	0	111.7	P456 P457 I458 F462 L463 L464 S529	P456-S460 WeakPolarHBondContact O-CB 3.27Å; P456-S460 PolarHBondContact O-N 3.43Å; P457-S460 WeakPolarHBondContact O-CB 3.42Å; I458-S460 VanDerWaalsContact C-N 3.26Å; I458-S460 PolarHBondContact O-N 3.03Å; S460-F462 PolarHBondContact O-N 3.08Å; S460-L463 PolarHBondContact O-N 2.91Å; S460-L464 VanDerWaalsContact O-CB 3.29Å; S460-L464 WeakPolarHBondContact O-CB 3.38Å; S460-L464 VanDerWaalsContact O-CG 3.25Å; S460-L464 WeakPolarHBondContact O-CG 3.18Å; S460-L464 PolarHBondContact O-N 3.22Å; S460-S529 VanDerWaalsContact OG-CA 3.28Å; S460-S529 WeakPolarHBondContact OG-CA 3.47Å; S460-S529 PolarHBondContact OG-N 3.34Å; S460-S529 PolarHBondContact OG-OG 3.09Å
461	V	94.9	Very high	90.9	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-64.7	-40.7	-179.4	171.4	0	0	0	0	112.4	L120 F124 P457 I458 L464 A465 A476 L480 V532	L120-V461 HydrophobicContact CD1-CG1 3.64Å; F124-V461 HydrophobicContact CE2-CG1 4.02Å; P457-V461 PolarHBondContact O-N 3.4Å; P457-V461 VanDerWaalsContact O-N 3.16Å; I458-V461 PolarHBondContact O-N 3.48Å; V461-L464 PolarHBondContact O-N 3.41Å; V461-A465 WeakPolarHBondContact O-CB 3.4Å; V461-A465 PolarHBondContact O-N 2.86Å; V461-A476 HydrophobicContact CG1-CB 4Å; V461-A476 HydrophobicContact CG2-CB 4.45Å; V461-L480 HydrophobicContact CB-CD2 4.31Å; V461-L480 HydrophobicContact CB-CG 4.49Å; V461-L480 HydrophobicContact CG2-CD1 4.26Å; V461-L480 HydrophobicContact CG2-CD2 3.83Å; V461-L480 HydrophobicContact CG2-CG 3.74Å; V461-V532 HydrophobicContact CG2-CG2 3.95Å
462	F	93.5	Very high	90.9	Very high	2 Å²	2	18.8 Å²	18.8	1%	0.009	9%	0.088	C	C	.	.	H	α-helix	trans	-66.1	-42.2	177.8	-89.7	-95.7	0	0	0	112.4	Y108 M116 Y119 L120 L133 S284 I458 A459 S460 A465 V466	Y108-F462 HydrophobicContact CE1-CE1 4.49Å; Y108-F462 VanDerWaalsContact OH-CD1 3.3Å; Y108-F462 WeakPolarHBondContact OH-CD1 3.44Å; M116-F462 HydrophobicContact CB-CE1 4.06Å; M116-F462 HydrophobicContact CB-CZ 3.77Å; Y119-F462 HydrophobicContact CD1-CD1 4.16Å; Y119-F462 AromaticContact CD1-CE1 3.78Å; Y119-F462 HydrophobicContact CD1-CE1 3.78Å; Y119-F462 HydrophobicContact CE1-CD1 4.29Å; Y119-F462 HydrophobicContact CE1-CE1 4.37Å; L120-F462 HydrophobicContact CD1-CD2 4.29Å; L120-F462 HydrophobicContact CD1-CE2 3.86Å; L120-F462 HydrophobicContact CD1-CZ 4.19Å; L120-F462 HydrophobicContact CD2-CD1 4.43Å; L120-F462 HydrophobicContact CD2-CE1 4.27Å; L120-F462 HydrophobicContact CD2-CE2 4.47Å; L120-F462 HydrophobicContact CD2-CZ 4.27Å; L120-F462 HydrophobicContact CG-CE1 4.34Å; L120-F462 HydrophobicContact CG-CE2 4.07Å; L120-F462 HydrophobicContact CG-CZ 3.88Å; L133-F462 HydrophobicContact CD1-CE2 3.71Å; L133-F462 HydrophobicContact CD1-CZ 4.15Å; S284-F462 WeakPolarHBondContact OG-CB 3.29Å; S284-F462 WeakPolarHBondContact OG-CG 3.5Å; I458-F462 HydrophobicContact CG2-CD2 3.75Å; I458-F462 HydrophobicContact CG2-CE2 3.83Å; I458-F462 WeakPolarHBondContact O-CD2 3.38Å; I458-F462 PolarHBondContact O-N 2.84Å; A459-F462 PolarHBondContact O-N 3.35Å; S460-F462 PolarHBondContact O-N 3.08Å; F462-A465 PolarHBondContact O-N 3.4Å; F462-V466 WeakPolarHBondContact O-CG2 3.49Å; F462-V466 PolarHBondContact O-N 3.49Å
463	L	92.6	Very high	90.8	Very high	40 Å²	40	20 Å²	20	21%	0.209	9%	0.093	C	C	.	.	H	α-helix	trans	-62.4	-48.7	176.3	-166.2	73.8	0	0	0	110.5	F104 A459 S460 A465 V466 F467 F525	F104-L463 HydrophobicContact CZ-CD1 4.09Å; A459-L463 VanDerWaalsContact O-CB 3.31Å; A459-L463 WeakPolarHBondContact O-CB 3.25Å; A459-L463 PolarHBondContact O-N 3.07Å; S460-L463 PolarHBondContact O-N 2.91Å; L463-A465 VanDerWaalsContact C-N 3.34Å; L463-A465 PolarHBondContact O-N 3.4Å; L463-V466 PolarHBondContact O-N 3.36Å; L463-F467 HydrophobicContact CD1-CD2 3.87Å; L463-F467 HydrophobicContact CD1-CE2 3.6Å; L463-F467 HydrophobicContact CG-CD2 3.97Å; L463-F467 HydrophobicContact CG-CE2 4.22Å; L463-F467 VanDerWaalsContact O-CD2 3.31Å; L463-F467 WeakPolarHBondContact O-CD2 3.48Å; L463-F467 PolarHBondContact O-N 3.01Å; L463-F525 HydrophobicContact CD2-CE2 4.48Å; L463-F525 HydrophobicContact CD2-CZ 3.78Å
464	L	91.9	Very high	90.8	Very high	17 Å²	17	22.5 Å²	22.5	9%	0.089	11%	0.109	C	C	.	.	H	α-helix	trans	-64.8	-35.6	178.4	-72.4	178	0	0	0	112.9	S460 V461 V466 F467 V468 V471 V532 L533	S460-L464 VanDerWaalsContact O-CB 3.29Å; S460-L464 WeakPolarHBondContact O-CB 3.38Å; S460-L464 VanDerWaalsContact O-CG 3.25Å; S460-L464 WeakPolarHBondContact O-CG 3.18Å; S460-L464 PolarHBondContact O-N 3.22Å; V461-L464 PolarHBondContact O-N 3.41Å; L464-V466 VanDerWaalsContact C-N 3.25Å; L464-V466 PolarHBondContact O-N 2.97Å; L464-F467 PolarHBondContact O-N 3.34Å; L464-V468 HydrophobicContact CD2-CG2 3.73Å; L464-V468 WeakPolarHBondContact O-CA 3.34Å; L464-V468 WeakPolarHBondContact O-CB 3.17Å; L464-V468 PolarHBondContact O-N 3.05Å; L464-V471 HydrophobicContact CB-CG2 4.21Å; L464-V532 HydrophobicContact CD1-CB 3.84Å; L464-V532 HydrophobicContact CD1-CG1 3.68Å; L464-V532 HydrophobicContact CD1-CG2 4.45Å; L464-L533 HydrophobicContact CD1-CG 4.42Å; L464-L533 HydrophobicContact CD2-CD2 4.15Å; L464-L533 HydrophobicContact CD2-CG 4.4Å
465	A	88.6	Confident	90.9	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-61.1	-35.1	176.1	0	0	0	0	0	112.5	Y119 L120 R123 F124 V461 F462 L463	Y119-A465 HydrophobicContact CE1-CB 4.27Å; L120-A465 HydrophobicContact CD2-CB 3.91Å; R123-A465 HydrophobicContact CG-CB 4.24Å; R123-A465 PolarHBondContact NE-O 3.32Å; F124-A465 HydrophobicContact CE2-CB 4.22Å; F124-A465 HydrophobicContact CZ-CB 3.7Å; V461-A465 WeakPolarHBondContact O-CB 3.4Å; V461-A465 PolarHBondContact O-N 2.86Å; F462-A465 PolarHBondContact O-N 3.4Å; L463-A465 VanDerWaalsContact C-N 3.34Å; L463-A465 PolarHBondContact O-N 3.4Å
466	V	85.1	Confident	91	Very high	5 Å²	5	21.7 Å²	21.7	3%	0.03	11%	0.105	C	C	.	.	H	α-helix	trans	-81.3	-40.4	179.1	174.5	0	0	0	0	112.1	L103 F104 F462 L463 L464 F551	L103-V466 HydrophobicContact CD1-CG1 4.18Å; L103-V466 HydrophobicContact CD2-CG1 4.45Å; L103-V466 HydrophobicContact CG-CG1 4.22Å; F104-V466 HydrophobicContact CD1-CG2 4.03Å; F104-V466 HydrophobicContact CE1-CG2 3.88Å; F462-V466 WeakPolarHBondContact O-CG2 3.49Å; F462-V466 PolarHBondContact O-N 3.49Å; L463-V466 PolarHBondContact O-N 3.36Å; L464-V466 VanDerWaalsContact C-N 3.25Å; L464-V466 PolarHBondContact O-N 2.97Å; V466-F551 WeakPolarHBondContact O-CE2 3.29Å
467	F	85.1	Confident	90.9	Very high	89 Å²	89	23.8 Å²	23.8	39%	0.39	11%	0.114	S	C	.	.	H	α-helix	trans	-96.8	-26	-171.9	-74.1	-72.3	0	0	0	115	L103 L463 L464 W554	L103-F467 HydrophobicContact CD1-CE1 4.39Å; L103-F467 HydrophobicContact CD1-CZ 4.08Å; L103-F467 HydrophobicContact CD2-CE1 4.4Å; L103-F467 HydrophobicContact CD2-CE2 3.6Å; L103-F467 HydrophobicContact CD2-CZ 3.35Å; L103-F467 HydrophobicContact CG-CZ 4.34Å; L463-F467 HydrophobicContact CD1-CD2 3.87Å; L463-F467 HydrophobicContact CD1-CE2 3.6Å; L463-F467 HydrophobicContact CG-CD2 3.97Å; L463-F467 HydrophobicContact CG-CE2 4.22Å; L463-F467 VanDerWaalsContact O-CD2 3.31Å; L463-F467 WeakPolarHBondContact O-CD2 3.48Å; L463-F467 PolarHBondContact O-N 3.01Å; L464-F467 PolarHBondContact O-N 3.34Å; F467-W554 AromaticContact CD1-CH2 3.97Å; F467-W554 HydrophobicContact CD1-CH2 3.97Å; F467-W554 AromaticContact CE1-CH2 3.97Å; F467-W554 HydrophobicContact CE1-CH2 3.97Å
468	V	85	Confident	90.8	Very high	38 Å²	38	30 Å²	30	23%	0.23	14%	0.137	C	C	.	.			trans	-116.3	113.1	-169.7	-172.2	0	0	0	0	111	R123 L464 R470 V471 L533	R123-V468 PolarHBondContact NH2-O 2.83Å; L464-V468 HydrophobicContact CD2-CG2 3.73Å; L464-V468 WeakPolarHBondContact O-CA 3.34Å; L464-V468 WeakPolarHBondContact O-CB 3.17Å; L464-V468 PolarHBondContact O-N 3.05Å; V468-R470 VanDerWaalsContact C-N 3.3Å; V468-R470 HydrophobicContact CG1-CB 4.29Å; V468-R470 PolarHBondContact O-N 3.15Å; V468-V471 HydrophobicContact CB-CG2 3.79Å; V468-V471 HydrophobicContact CG1-CG2 3.73Å; V468-L533 HydrophobicContact CG1-CD2 4.14Å
469	K	81.3	Confident	90.8	Very high	97 Å²	97	29.7 Å²	29.7	42%	0.422	14%	0.136	S	C	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-40.5	177.6	-167.7	-179.9	172.1	-171.7	0	112	R123 V471 D544 F551	R123-K469 PolarHBondContact NH2-O 3.17Å; K469-V471 VanDerWaalsContact C-N 3.3Å; K469-V471 PolarHBondContact O-N 2.97Å; K469-D544 IonicContact NZ-OD1 2.78Å; K469-D544 PolarHBondContact NZ-OD1 3.1Å; K469-D544 VanDerWaalsContact NZ-OD1 3.14Å; K469-F551 HydrophobicContact CB-CE1 3.63Å; K469-F551 HydrophobicContact CB-CZ 4.08Å; K469-F551 HydrophobicContact CD-CE1 4.31Å; K469-F551 HydrophobicContact CG-CD1 4.39Å; K469-F551 HydrophobicContact CG-CE1 3.68Å
470	R	85.1	Confident	90.8	Very high	67 Å²	67	29.8 Å²	29.8	25%	0.253	14%	0.136	S	C	.	.	T	Hydrogen-bonded Turn	trans	-70.7	-21.6	-168.6	-173.4	60.4	178.1	98.7	-4.5	114.5	V468 N472 S536 F537 T539 E540	V468-R470 VanDerWaalsContact C-N 3.3Å; V468-R470 HydrophobicContact CG1-CB 4.29Å; V468-R470 PolarHBondContact O-N 3.15Å; R470-N472 PolarHBondContact O-N 3.47Å; R470-S536 PolarHBondContact NH1-O 2.9Å; R470-S536 PolarHBondContact NH2-O 2.85Å; R470-F537 HydrophobicContact CB-CE1 4.24Å; R470-F537 HydrophobicContact CB-CZ 4.23Å; R470-F537 HydrophobicContact CG-CD1 3.77Å; R470-F537 HydrophobicContact CG-CE1 3.59Å; R470-F537 HydrophobicContact CG-CG 4.34Å; R470-F537 HydrophobicContact CG-CZ 3.98Å; R470-F537 PolarHBondContact NH2-O 2.95Å; R470-T539 PolarHBondContact NH1-O 3.22Å; R470-T539 PolarHBondContact NH2-O 3.29Å; R470-E540 PolarHBondContact NH1-O 2.72Å
471	V	89.3	Confident	90.7	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	15%	0.149	C	C	.	.			trans	-64.2	123.4	-178.1	173.7	0	0	0	0	109.7	F124 L464 V468 K469 V532 L533 S536 I542	F124-V471 HydrophobicContact CE1-CB 4.38Å; F124-V471 HydrophobicContact CE1-CG1 3.86Å; F124-V471 VanDerWaalsContact CE1-O 3.25Å; F124-V471 WeakPolarHBondContact CE1-O 3.46Å; F124-V471 HydrophobicContact CZ-CG1 3.86Å; L464-V471 HydrophobicContact CB-CG2 4.21Å; V468-V471 HydrophobicContact CB-CG2 3.79Å; V468-V471 HydrophobicContact CG1-CG2 3.73Å; K469-V471 VanDerWaalsContact C-N 3.3Å; K469-V471 PolarHBondContact O-N 2.97Å; V471-V532 HydrophobicContact CG1-CG1 3.58Å; V471-V532 HydrophobicContact CG2-CG1 4.16Å; V471-L533 HydrophobicContact CG2-CD2 3.96Å; V471-S536 WeakPolarHBondContact CA-OG 3.3Å; V471-I542 WeakPolarHBondContact O-CD1 3.18Å
472	N	90.4	Very high	90.8	Very high	7 Å²	7	34.6 Å²	34.6	4%	0.037	16%	0.164	C	C	.	.			trans	-112.1	175.4	-176	66.3	10	0	0	0	112.5	R470 T474 G475 A476 S536 T539 E540 I542	R470-N472 PolarHBondContact O-N 3.47Å; N472-T474 PolarHBondContact O-N 3.1Å; N472-G475 PolarHBondContact OD1-N 2.99Å; N472-A476 WeakPolarHBondContact O-CB 3.46Å; N472-A476 PolarHBondContact O-N 3.08Å; N472-S536 PolarHBondContact N-OG 3.22Å; N472-S536 WeakPolarHBondContact OD1-CA 3.28Å; N472-S536 WeakPolarHBondContact OD1-CB 3.35Å; N472-S536 PolarHBondContact OD1-OG 3.42Å; N472-T539 PolarHBondContact ND2-OG1 3.49Å; N472-E540 PolarHBondContact ND2-O 3.22Å; N472-I542 HydrophobicContact CB-CD1 4.19Å; N472-I542 HydrophobicContact CB-CG1 3.55Å
473	E	90.6	Very high	90.9	Very high	31 Å²	31	34.5 Å²	34.5	15%	0.145	16%	0.164	C	C	.	.	H	α-helix	trans	-59.5	-47.1	-177.7	-163.5	-78.7	167.8	0	0	112.1	F124 I129 G475 A476 F477	F124-E473 HydrophobicContact CB-CB 4.02Å; F124-E473 HydrophobicContact CB-CG 4.25Å; I129-E473 HydrophobicContact CD1-CB 4.36Å; I129-E473 HydrophobicContact CD1-CG 3.72Å; I129-E473 HydrophobicContact CG1-CG 4.32Å; E473-G475 PolarHBondContact O-N 3.47Å; E473-A476 PolarHBondContact O-N 3.14Å; E473-F477 WeakPolarHBondContact O-CB 3.3Å; E473-F477 PolarHBondContact O-N 3.42Å
474	T	91.6	Very high	91	Very high	54 Å²	54	34.4 Å²	34.4	33%	0.331	16%	0.163	S	C	.	.	H	α-helix	trans	-64	-42.9	-176.2	-50.2	0	0	0	0	111.9	N472 F477 W478 V535 T539	N472-T474 PolarHBondContact O-N 3.1Å; T474-F477 PolarHBondContact O-N 3.17Å; T474-W478 VanDerWaalsContact O-CD1 3.32Å; T474-W478 PolarHBondContact O-N 2.93Å; T474-V535 HydrophobicContact CG2-CG1 4.21Å; T474-T539 HydrophobicContact CG2-CG2 4.27Å
475	G	93.1	Very high	91.2	Very high	0 Å²	0	36 Å²	36	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-67.2	-41.9	176	0	0	0	0	0	112.8	N472 E473 G479	N472-G475 PolarHBondContact OD1-N 2.99Å; E473-G475 PolarHBondContact O-N 3.47Å; G475-G479 WeakPolarHBondContact O-CA 3.39Å; G475-G479 PolarHBondContact O-N 3.5Å
476	A	93.5	Very high	91.4	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-63.7	-42.7	175.3	0	0	0	0	0	112.1	F124 I129 V461 N472 E473 L480	F124-A476 HydrophobicContact CD2-CB 4.14Å; F124-A476 HydrophobicContact CE2-CB 3.79Å; F124-A476 HydrophobicContact CZ-CB 4.18Å; I129-A476 HydrophobicContact CD1-CB 3.71Å; V461-A476 HydrophobicContact CG1-CB 4Å; V461-A476 HydrophobicContact CG2-CB 4.45Å; N472-A476 WeakPolarHBondContact O-CB 3.46Å; N472-A476 PolarHBondContact O-N 3.08Å; E473-A476 PolarHBondContact O-N 3.14Å; A476-L480 WeakPolarHBondContact O-CB 3.32Å; A476-L480 WeakPolarHBondContact O-CG 3.44Å; A476-L480 PolarHBondContact O-N 3.48Å
477	F	94.1	Very high	91.8	Very high	43 Å²	43	38.6 Å²	38.6	19%	0.189	19%	0.191	C	C	.	.	H	α-helix	trans	-65	-53.7	179.4	179.1	-99.8	0	0	0	112.2	R128 I129 E473 T474 G479 L480 I481	R128-F477 HydrophobicContact CB-CD2 4.15Å; R128-F477 HydrophobicContact CB-CE2 4.17Å; I129-F477 HydrophobicContact CG1-CB 4.08Å; I129-F477 HydrophobicContact CG1-CD2 4.44Å; E473-F477 WeakPolarHBondContact O-CB 3.3Å; E473-F477 PolarHBondContact O-N 3.42Å; T474-F477 PolarHBondContact O-N 3.17Å; F477-G479 VanDerWaalsContact C-N 3.34Å; F477-G479 PolarHBondContact O-N 2.89Å; F477-L480 PolarHBondContact O-N 2.85Å; F477-I481 HydrophobicContact CD1-CG1 4.36Å; F477-I481 HydrophobicContact CE1-CG1 3.96Å; F477-I481 HydrophobicContact CE2-CD1 4.33Å; F477-I481 HydrophobicContact CE2-CG1 4.15Å; F477-I481 HydrophobicContact CZ-CD1 4.1Å; F477-I481 HydrophobicContact CZ-CG1 3.85Å; F477-I481 WeakPolarHBondContact O-CG1 3.33Å; F477-I481 PolarHBondContact O-N 2.79Å
478	W	94.3	Very high	92.2	Very high	133 Å²	133	37 Å²	37	50%	0.504	19%	0.187	S	C	.	.	H	α-helix	trans	-67.1	-36.1	179.6	-77.8	110.1	0	0	0	112.4	T474 L480 I481 C482	T474-W478 VanDerWaalsContact O-CD1 3.32Å; T474-W478 PolarHBondContact O-N 2.93Å; W478-L480 VanDerWaalsContact C-N 3.32Å; W478-L480 PolarHBondContact O-N 3.31Å; W478-I481 HydrophobicContact CE3-CG2 4.47Å; W478-I481 PolarHBondContact O-N 2.91Å; W478-C482 VanDerWaalsContact O-CB 3.3Å; W478-C482 WeakPolarHBondContact O-CB 3.34Å; W478-C482 PolarHBondContact O-N 3.49Å; W478-C482 PolarHBondContact O-SG 3.2Å; W478-C482 VanDerWaalsContact O-SG 3.34Å
479	G	95.4	Very high	92.5	Very high	1 Å²	1	39.5 Å²	39.5	1%	0.01	21%	0.205	C	C	.	.	H	α-helix	trans	-58.5	-44	171.9	0	0	0	0	0	112.3	G475 F477 G483 T528	G475-G479 WeakPolarHBondContact O-CA 3.39Å; G475-G479 PolarHBondContact O-N 3.5Å; F477-G479 VanDerWaalsContact C-N 3.34Å; F477-G479 PolarHBondContact O-N 2.89Å; G479-G483 WeakPolarHBondContact O-CA 3.23Å; G479-G483 PolarHBondContact O-N 3.4Å; G479-T528 WeakPolarHBondContact O-CG2 3.24Å
480	L	94.8	Very high	92.8	Very high	1 Å²	1	35.3 Å²	35.3	1%	0.005	19%	0.186	C	C	.	.	H	α-helix	trans	-65.8	-44.4	175.9	-75.1	168.9	0	0	0	112.7	I129 Y132 L133 P457 I458 V461 A476 F477 W478 G483 L484	I129-L480 HydrophobicContact CG2-CD1 4.18Å; Y132-L480 HydrophobicContact CD1-CB 4.19Å; Y132-L480 HydrophobicContact CD1-CD1 3.9Å; Y132-L480 HydrophobicContact CE1-CB 3.49Å; Y132-L480 VanDerWaalsContact CE1-CB 3.49Å; Y132-L480 HydrophobicContact CE1-CD1 3.85Å; Y132-L480 HydrophobicContact CE1-CD2 4.12Å; Y132-L480 HydrophobicContact CE1-CG 4Å; Y132-L480 PolarHBondContact OH-O 3.15Å; L133-L480 HydrophobicContact CD2-CD1 4.23Å; L133-L480 HydrophobicContact CD2-CD2 4.46Å; P457-L480 HydrophobicContact CB-CD2 4.17Å; P457-L480 WeakPolarHBondContact O-CD2 3.43Å; I458-L480 HydrophobicContact CG1-CD2 4.31Å; V461-L480 HydrophobicContact CB-CD2 4.31Å; V461-L480 HydrophobicContact CB-CG 4.49Å; V461-L480 HydrophobicContact CG2-CD1 4.26Å; V461-L480 HydrophobicContact CG2-CD2 3.83Å; V461-L480 HydrophobicContact CG2-CG 3.74Å; A476-L480 WeakPolarHBondContact O-CB 3.32Å; A476-L480 WeakPolarHBondContact O-CG 3.44Å; A476-L480 PolarHBondContact O-N 3.48Å; F477-L480 PolarHBondContact O-N 2.85Å; W478-L480 VanDerWaalsContact C-N 3.32Å; W478-L480 PolarHBondContact O-N 3.31Å; L480-G483 PolarHBondContact O-N 2.82Å; L480-L484 WeakPolarHBondContact O-CB 3.34Å; L480-L484 PolarHBondContact O-N 3.33Å
481	I	95.2	Very high	93	Very high	55 Å²	55	33.3 Å²	33.3	28%	0.282	18%	0.18	S	C	.	.	H	α-helix	trans	-65.2	-49.8	-179.6	-67.4	-72.6	0	0	0	111.1	Y132 F477 W478 G483 L484 A485	Y132-I481 HydrophobicContact CD2-CD1 3.85Å; Y132-I481 HydrophobicContact CE2-CD1 3.5Å; Y132-I481 VanDerWaalsContact CE2-CD1 3.5Å; Y132-I481 HydrophobicContact CE2-CG1 4.35Å; F477-I481 HydrophobicContact CD1-CG1 4.36Å; F477-I481 HydrophobicContact CE1-CG1 3.96Å; F477-I481 HydrophobicContact CE2-CD1 4.33Å; F477-I481 HydrophobicContact CE2-CG1 4.15Å; F477-I481 HydrophobicContact CZ-CD1 4.1Å; F477-I481 HydrophobicContact CZ-CG1 3.85Å; F477-I481 WeakPolarHBondContact O-CG1 3.33Å; F477-I481 PolarHBondContact O-N 2.79Å; W478-I481 HydrophobicContact CE3-CG2 4.47Å; W478-I481 PolarHBondContact O-N 2.91Å; I481-G483 VanDerWaalsContact C-N 3.32Å; I481-G483 PolarHBondContact O-N 3Å; I481-L484 PolarHBondContact O-N 2.76Å; I481-A485 WeakPolarHBondContact O-CB 3.27Å; I481-A485 PolarHBondContact O-N 3.46Å
482	C	96.1	Very high	93	Very high	46 Å²	46	38.5 Å²	38.5	31%	0.311	21%	0.207	S	C	.	.	H	α-helix	trans	-65	-38.6	176.8	-66.2	0	0	0	0	111.2	W478 A485 M486 L531	W478-C482 VanDerWaalsContact O-CB 3.3Å; W478-C482 WeakPolarHBondContact O-CB 3.34Å; W478-C482 PolarHBondContact O-N 3.49Å; W478-C482 PolarHBondContact O-SG 3.2Å; W478-C482 VanDerWaalsContact O-SG 3.34Å; C482-A485 PolarHBondContact O-N 3.14Å; C482-M486 WeakPolarHBondContact O-CG 3.11Å; C482-M486 PolarHBondContact O-N 2.85Å; C482-L531 HydrophobicContact CB-CD1 3.85Å
483	G	95.7	Very high	92.8	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-58.7	-48.2	172.9	0	0	0	0	0	112.4	G479 L480 I481 A485 M486 G487 L524	G479-G483 WeakPolarHBondContact O-CA 3.23Å; G479-G483 PolarHBondContact O-N 3.4Å; L480-G483 PolarHBondContact O-N 2.82Å; I481-G483 VanDerWaalsContact C-N 3.32Å; I481-G483 PolarHBondContact O-N 3Å; G483-A485 PolarHBondContact O-N 3.2Å; G483-M486 PolarHBondContact O-N 3.26Å; G483-G487 PolarHBondContact O-N 3.12Å; G483-L524 WeakPolarHBondContact O-CD1 3.49Å
484	L	94.6	Very high	92.4	Very high	39 Å²	39	39.2 Å²	39.2	20%	0.204	21%	0.213	C	C	.	.	H	α-helix	trans	-61.5	-44.6	175.1	178.3	68.3	0	0	0	111.5	Y132 I136 L454 L480 I481 M486 G487 L488	Y132-L484 HydrophobicContact CE2-CD2 4.23Å; Y132-L484 VanDerWaalsContact OH-CB 3.3Å; Y132-L484 WeakPolarHBondContact OH-CB 3.47Å; I136-L484 HydrophobicContact CD1-CD1 4.07Å; I136-L484 HydrophobicContact CD1-CD2 3.68Å; I136-L484 HydrophobicContact CD1-CG 4.35Å; L454-L484 HydrophobicContact CD2-CD1 3.63Å; L480-L484 WeakPolarHBondContact O-CB 3.34Å; L480-L484 PolarHBondContact O-N 3.33Å; I481-L484 PolarHBondContact O-N 2.76Å; L484-M486 VanDerWaalsContact C-N 3.35Å; L484-M486 PolarHBondContact O-N 2.99Å; L484-G487 PolarHBondContact O-N 3.47Å; L484-L488 HydrophobicContact CD1-CD1 4.19Å; L484-L488 HydrophobicContact CD1-CD2 4.48Å; L484-L488 HydrophobicContact CD1-CG 4.06Å; L484-L488 HydrophobicContact CD2-CD1 4.37Å; L484-L488 HydrophobicContact CG-CD1 3.91Å; L484-L488 HydrophobicContact CG-CG 4.17Å; L484-L488 WeakPolarHBondContact O-CB 3.44Å; L484-L488 VanDerWaalsContact O-CG 3.31Å; L484-L488 WeakPolarHBondContact O-CG 3.38Å; L484-L488 PolarHBondContact O-N 2.92Å
485	A	95.4	Very high	91.9	Very high	49 Å²	49	40 Å²	40	41%	0.405	21%	0.212	S	C	.	.	H	α-helix	trans	-58.3	-47.4	177.5	0	0	0	0	0	111.2	I481 C482 G483 G487 L488 C489	I481-A485 WeakPolarHBondContact O-CB 3.27Å; I481-A485 PolarHBondContact O-N 3.46Å; C482-A485 PolarHBondContact O-N 3.14Å; G483-A485 PolarHBondContact O-N 3.2Å; A485-G487 VanDerWaalsContact C-N 3.33Å; A485-G487 PolarHBondContact O-N 3.1Å; A485-L488 PolarHBondContact O-N 3.27Å; A485-C489 WeakPolarHBondContact O-CB 3.5Å; A485-C489 PolarHBondContact O-N 3.45Å; A485-C489 PolarHBondContact O-SG 2.87Å
486	M	94.7	Very high	91.4	Very high	61 Å²	61	50.3 Å²	50.3	30%	0.3	25%	0.251	S	S	.	.	H	α-helix	trans	-58.9	-43.3	174.8	-72.1	-175.7	-68.2	0	0	112.1	C482 G483 L484 C489 R490 L524 C527 L531	C482-M486 WeakPolarHBondContact O-CG 3.11Å; C482-M486 PolarHBondContact O-N 2.85Å; G483-M486 PolarHBondContact O-N 3.26Å; L484-M486 VanDerWaalsContact C-N 3.35Å; L484-M486 PolarHBondContact O-N 2.99Å; M486-C489 PolarHBondContact O-N 3.3Å; M486-R490 PolarHBondContact O-N 2.98Å; M486-L524 HydrophobicContact CB-CD1 3.61Å; M486-L524 HydrophobicContact CE-CD1 4Å; M486-C527 HydrophobicContact CE-CB 3.9Å; M486-C527 HydrophobicContact SD-CB 4Å; M486-L531 HydrophobicContact CE-CD1 4Å
487	G	93.5	Very high	90.8	Very high	0 Å²	0	54.7 Å²	54.7	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-60.8	-47.8	175.3	0	0	0	0	0	113	Y453 G483 L484 A485 C489 R490 M491	Y453-G487 VanDerWaalsContact O-CA 3.23Å; Y453-G487 WeakPolarHBondContact O-CA 3.25Å; G483-G487 PolarHBondContact O-N 3.12Å; L484-G487 PolarHBondContact O-N 3.47Å; A485-G487 VanDerWaalsContact C-N 3.33Å; A485-G487 PolarHBondContact O-N 3.1Å; G487-C489 VanDerWaalsContact C-N 3.34Å; G487-C489 PolarHBondContact O-N 3.17Å; G487-R490 PolarHBondContact O-N 3.25Å; G487-R490 VanDerWaalsContact O-N 3.15Å; G487-M491 WeakPolarHBondContact O-CB 3.43Å; G487-M491 PolarHBondContact O-N 3.35Å
488	L	92.2	Very high	89.7	Confident	55 Å²	55	54.1 Å²	54.1	29%	0.288	28%	0.276	S	S	.	.	H	α-helix	trans	-65.8	-34.8	178	-68.4	179	0	0	0	112.4	L454 L484 A485 R490 M491 L492	L454-L488 HydrophobicContact CD2-CD2 4.14Å; L484-L488 HydrophobicContact CD1-CD1 4.19Å; L484-L488 HydrophobicContact CD1-CD2 4.48Å; L484-L488 HydrophobicContact CD1-CG 4.06Å; L484-L488 HydrophobicContact CD2-CD1 4.37Å; L484-L488 HydrophobicContact CG-CD1 3.91Å; L484-L488 HydrophobicContact CG-CG 4.17Å; L484-L488 WeakPolarHBondContact O-CB 3.44Å; L484-L488 VanDerWaalsContact O-CG 3.31Å; L484-L488 WeakPolarHBondContact O-CG 3.38Å; L484-L488 PolarHBondContact O-N 2.92Å; A485-L488 PolarHBondContact O-N 3.27Å; L488-R490 PolarHBondContact O-N 3.25Å; L488-M491 HydrophobicContact CD2-CE 3.46Å; L488-M491 VanDerWaalsContact CD2-CE 3.46Å; L488-M491 PolarHBondContact O-N 3.27Å; L488-L492 HydrophobicContact CB-CD1 4.35Å; L488-L492 WeakPolarHBondContact O-CB 3.36Å; L488-L492 WeakPolarHBondContact O-CG 3.43Å; L488-L492 PolarHBondContact O-N 3.07Å
489	C	91.3	Very high	88.3	Confident	90 Å²	90	49.8 Å²	49.8	61%	0.608	27%	0.265	S	S	*	.	H	α-helix	trans	-60.3	-28.5	173.5	-74.3	0	0	0	0	112.7	A485 M486 G487 P493	A485-C489 WeakPolarHBondContact O-CB 3.5Å; A485-C489 PolarHBondContact O-N 3.45Å; A485-C489 PolarHBondContact O-SG 2.87Å; M486-C489 PolarHBondContact O-N 3.3Å; G487-C489 VanDerWaalsContact C-N 3.34Å; G487-C489 PolarHBondContact O-N 3.17Å; C489-P493 WeakPolarHBondContact O-CD 3.47Å; C489-P493 WeakPolarHBondContact O-CG 3.27Å
490	R	88.6	Confident	87	Confident	10 Å²	10	50.8 Å²	50.8	4%	0.038	28%	0.275	C	S	.	.	H	α-helix	trans	-87.5	-40.4	173.5	176.5	64.6	-178.7	73.8	2.2	112.3	Y453 M486 G487 L488 E494 V512 C513 I515 F520	Y453-R490 HydrophobicContact CD1-CG 3.91Å; Y453-R490 HydrophobicContact CE1-CG 3.68Å; Y453-R490 PolarHBondContact OH-NH1 3.41Å; Y453-R490 PolarHBondContact OH-NH2 3.03Å; M486-R490 PolarHBondContact O-N 2.98Å; G487-R490 PolarHBondContact O-N 3.25Å; G487-R490 VanDerWaalsContact O-N 3.15Å; L488-R490 PolarHBondContact O-N 3.25Å; R490-E494 IonicContact CZ-OE2 3.62Å; R490-E494 IonicContact NH1-OE1 3.82Å; R490-E494 IonicContact NH1-OE2 3.46Å; R490-E494 PolarHBondContact NH1-OE2 2.99Å; R490-E494 IonicContact NH2-OE1 2.6Å; R490-E494 IonicContact NH2-OE2 3.77Å; R490-V512 WeakPolarHBondContact CD-O 3.44Å; R490-V512 PolarHBondContact NE-O 3.38Å; R490-V512 VanDerWaalsContact NE-O 3.08Å; R490-C513 PolarHBondContact NH2-O 3.37Å; R490-I515 PolarHBondContact NH2-O 2.9Å; R490-F520 HydrophobicContact CB-CD1 4.38Å; R490-F520 HydrophobicContact CB-CD2 4.42Å; R490-F520 HydrophobicContact CB-CE1 3.7Å; R490-F520 HydrophobicContact CB-CE2 3.77Å; R490-F520 HydrophobicContact CB-CZ 3.36Å; R490-F520 HydrophobicContact CG-CD1 4.07Å; R490-F520 HydrophobicContact CG-CD2 4.11Å; R490-F520 HydrophobicContact CG-CE1 3.9Å; R490-F520 HydrophobicContact CG-CE2 3.97Å; R490-F520 HydrophobicContact CG-CG 4.16Å; R490-F520 HydrophobicContact CG-CZ 3.86Å
491	M	88.6	Confident	86	Confident	25 Å²	25	51.6 Å²	51.6	12%	0.123	28%	0.281	C	S	.	.	H	α-helix	trans	-70.8	-51.9	-174.8	-169.9	-179.5	84.9	0	0	111.8	V450 Y453 L454 G487 L488 E494 F495	V450-M491 HydrophobicContact CG1-SD 4.41Å; Y453-M491 HydrophobicContact CD2-CB 3.91Å; Y453-M491 HydrophobicContact CD2-CG 3.92Å; Y453-M491 HydrophobicContact CG-CB 4.34Å; L454-M491 HydrophobicContact CD1-SD 3.97Å; L454-M491 HydrophobicContact CD2-SD 4.31Å; L454-M491 HydrophobicContact CG-SD 4.17Å; G487-M491 WeakPolarHBondContact O-CB 3.43Å; G487-M491 PolarHBondContact O-N 3.35Å; L488-M491 HydrophobicContact CD2-CE 3.46Å; L488-M491 VanDerWaalsContact CD2-CE 3.46Å; L488-M491 PolarHBondContact O-N 3.27Å; M491-E494 PolarHBondContact O-N 3.16Å; M491-E494 VanDerWaalsContact O-N 3.14Å; M491-F495 HydrophobicContact CG-CD2 3.62Å; M491-F495 HydrophobicContact CG-CE2 3.5Å; M491-F495 WeakPolarHBondContact O-CD2 3.38Å; M491-F495 PolarHBondContact O-N 3.07Å; M491-F495 HydrophobicContact SD-CE2 4.21Å
492	L	88.6	Confident	84.9	Confident	108 Å²	108	53.5 Å²	53.5	57%	0.565	30%	0.298	S	S	*	.	H	α-helix	trans	-59.6	-44.8	-174.1	-65.8	172.7	0	0	0	113.1	L488 E494 F495 W496	L488-L492 HydrophobicContact CB-CD1 4.35Å; L488-L492 WeakPolarHBondContact O-CB 3.36Å; L488-L492 WeakPolarHBondContact O-CG 3.43Å; L488-L492 PolarHBondContact O-N 3.07Å; L492-E494 VanDerWaalsContact C-N 3.34Å; L492-E494 PolarHBondContact O-N 3.11Å; L492-F495 PolarHBondContact O-N 2.67Å; L492-W496 WeakPolarHBondContact O-CB 2.99Å; L492-W496 PolarHBondContact O-N 3.46Å
493	P	86.9	Confident	83.7	Confident	32 Å²	32	52 Å²	52	21%	0.208	29%	0.286	C	S	.	.	H	α-helix	trans	-64.1	-37.1	176.1	-26	39.2	0	0	0	113	C489 W496 F497 V512	C489-P493 WeakPolarHBondContact O-CD 3.47Å; C489-P493 WeakPolarHBondContact O-CG 3.27Å; P493-W496 PolarHBondContact O-N 3.04Å; P493-F497 HydrophobicContact CB-CD2 4.21Å; P493-F497 HydrophobicContact CB-CE2 4.42Å; P493-F497 WeakPolarHBondContact O-CB 3.35Å; P493-F497 WeakPolarHBondContact O-CD2 3.4Å; P493-F497 PolarHBondContact O-N 3.22Å; P493-V512 HydrophobicContact CB-CG1 3.85Å; P493-V512 HydrophobicContact CG-CG1 3.91Å
494	E	82.8	Confident	82.6	Confident	22 Å²	22	56 Å²	56	10%	0.103	30%	0.304	C	S	.	.	H	α-helix	trans	-66.1	-38.7	177.7	-176.6	171.9	-146.2	0	0	112.5	Y453 R490 M491 L492 G498 T499	Y453-E494 WeakPolarHBondContact CE2-OE2 3.33Å; Y453-E494 PolarHBondContact OH-OE1 2.97Å; Y453-E494 PolarHBondContact OH-OE2 3.02Å; R490-E494 IonicContact CZ-OE2 3.62Å; R490-E494 IonicContact NH1-OE1 3.82Å; R490-E494 IonicContact NH1-OE2 3.46Å; R490-E494 PolarHBondContact NH1-OE2 2.99Å; R490-E494 IonicContact NH2-OE1 2.6Å; R490-E494 IonicContact NH2-OE2 3.77Å; M491-E494 PolarHBondContact O-N 3.16Å; M491-E494 VanDerWaalsContact O-N 3.14Å; L492-E494 VanDerWaalsContact C-N 3.34Å; L492-E494 PolarHBondContact O-N 3.11Å; E494-G498 CarbonylContact O-C 3.6Å; E494-G498 WeakPolarHBondContact O-CA 3.44Å; E494-G498 PolarHBondContact O-N 3.5Å; E494-T499 HydrophobicContact CG-CG2 3.57Å; E494-T499 PolarHBondContact O-N 3.4Å
495	F	81.2	Confident	81.6	Confident	70 Å²	70	59.2 Å²	59.2	31%	0.307	33%	0.327	S	S	.	.	H	α-helix	trans	-69.6	-33.6	172.9	-84.1	-86.7	0	0	0	112.5	A438 Y446 V450 M491 L492	A438-F495 HydrophobicContact CB-CD1 4.08Å; A438-F495 HydrophobicContact CB-CE1 3.64Å; Y446-F495 AromaticContact CE2-CE1 3.77Å; Y446-F495 HydrophobicContact CE2-CE1 3.77Å; Y446-F495 AromaticContact CE2-CZ 3.63Å; Y446-F495 HydrophobicContact CE2-CZ 3.63Å; V450-F495 HydrophobicContact CG2-CE2 4Å; V450-F495 HydrophobicContact CG2-CZ 3.74Å; M491-F495 HydrophobicContact CG-CD2 3.62Å; M491-F495 HydrophobicContact CG-CE2 3.5Å; M491-F495 WeakPolarHBondContact O-CD2 3.38Å; M491-F495 PolarHBondContact O-N 3.07Å; M491-F495 HydrophobicContact SD-CE2 4.21Å; L492-F495 PolarHBondContact O-N 2.67Å
496	W	82.4	Confident	80.6	Confident	216 Å²	216	59.8 Å²	59.8	82%	0.818	33%	0.328	S	S	*	.	H	α-helix	trans	-74.6	-45.2	-179	-170.1	-86.2	0	0	0	112.9	L492 P493	L492-W496 WeakPolarHBondContact O-CB 2.99Å; L492-W496 PolarHBondContact O-N 3.46Å; P493-W496 PolarHBondContact O-N 3.04Å
497	F	79.8	Confident	79.6	Confident	92 Å²	92	64.6 Å²	64.6	40%	0.404	35%	0.35	S	S	.	.	H	α-helix	trans	-88.4	-7	-179.9	-67.7	-69.7	0	0	0	113.5	P493 C508	P493-F497 HydrophobicContact CB-CD2 4.21Å; P493-F497 HydrophobicContact CB-CE2 4.42Å; P493-F497 WeakPolarHBondContact O-CB 3.35Å; P493-F497 WeakPolarHBondContact O-CD2 3.4Å; P493-F497 PolarHBondContact O-N 3.22Å; F497-C508 HydrophobicContact CB-CB 3.87Å; F497-C508 HydrophobicContact CD2-CB 4.45Å; F497-C508 HydrophobicContact CG-CB 4.43Å
498	G	71.5	Confident	78.9	Confident	31 Å²	31	65.3 Å²	65.3	32%	0.32	36%	0.355	S	S	.	.			trans	83.6	140	-173.7	0	0	0	0	0	112.6	E494 G500 S506	E494-G498 CarbonylContact O-C 3.6Å; E494-G498 WeakPolarHBondContact O-CA 3.44Å; E494-G498 PolarHBondContact O-N 3.5Å; G498-G500 PolarHBondContact O-N 2.94Å; G498-G500 VanDerWaalsContact O-N 3.16Å; G498-S506 WeakPolarHBondContact O-CB 3.31Å
499	T	65.8	Low	78.3	Confident	43 Å²	43	65.8 Å²	65.8	26%	0.264	36%	0.361	S	S	.	.			trans	-62.4	-16.8	174	43.6	0	0	0	0	112.8	E494	E494-T499 HydrophobicContact CG-CG2 3.57Å; E494-T499 PolarHBondContact O-N 3.4Å
500	G	68.1	Low	77.6	Confident	21 Å²	21	69.9 Å²	69.9	22%	0.216	37%	0.369	C	S	.	.			trans	74.6	145.4	-172.4	0	0	0	0	0	111.4	S440 G498 F504	S440-G500 VanDerWaalsContact CB-O 3.25Å; S440-G500 WeakPolarHBondContact CB-O 3.25Å; G498-G500 PolarHBondContact O-N 2.94Å; G498-G500 VanDerWaalsContact O-N 3.16Å; G500-F504 CarbonylContact C-O 3.05Å; G500-F504 WeakPolarHBondContact CA-O 3.19Å
501	S	72.3	Confident	76.8	Confident	19 Å²	19	77 Å²	77	13%	0.133	41%	0.407	C	S	.	.			trans	-120	171.9	164.9	73.1	0	0	0	0	108.8	I503 F504	S501-I503 PolarHBondContact O-N 3.47Å; S501-I503 VanDerWaalsContact O-N 3.12Å; S501-I503 PolarHBondContact OG-N 3.49Å; S501-F504 PolarHBondContact N-O 3.35Å; S501-F504 CarbonylContact O-C 3.3Å; S501-F504 VanDerWaalsContact O-C 3.25Å; S501-F504 PolarHBondContact O-N 3.08Å; S501-F504 VanDerWaalsContact O-O 3.09Å; S501-F504 WeakPolarHBondContact OG-CD2 3.45Å; S501-F504 PolarHBondContact OG-N 3.46Å
502	C	72.3	Confident	76.2	Confident	94 Å²	94	78.4 Å²	78.4	64%	0.635	42%	0.417	S	S	*	.	S	Bend	trans	-53.1	-30.1	170.9	-81.2	0	0	0	0	112.8	C246	C246-C502 HydrophobicContact CB-CB 3.81Å; C246-C502 VanDerWaalsContact SG-CB 3.58Å; C246-C502 PolarHBondContact SG-O 3.25Å; C246-C502 VanDerWaalsContact SG-O 3.33Å
503	I	71.6	Confident	75.7	Confident	15 Å²	15	74.3 Å²	74.3	8%	0.077	40%	0.397	C	S	.	.	S	Bend	trans	-91.2	-39	-178.3	-54.5	165.5	0	0	0	111.1	Y240 V337 P339 E349 S501 P505	Y240-I503 HydrophobicContact CD1-CG2 4.09Å; V337-I503 WeakPolarHBondContact O-CD1 3.26Å; P339-I503 HydrophobicContact CG-CD1 4.3Å; P339-I503 HydrophobicContact CG-CG2 4.32Å; E349-I503 WeakPolarHBondContact O-CD1 3.35Å; S501-I503 PolarHBondContact O-N 3.47Å; S501-I503 VanDerWaalsContact O-N 3.12Å; S501-I503 PolarHBondContact OG-N 3.49Å; I503-P505 WeakPolarHBondContact O-CD 3.47Å
504	F	73.8	Confident	75.3	Confident	84 Å²	84	74.4 Å²	74.4	37%	0.368	40%	0.404	S	S	.	.	S	Bend	trans	-113.6	90.8	-179	-58.4	-71.1	0	0	0	109.1	Y240 V350 G500 S501 S506	Y240-F504 HydrophobicContact CD1-CE1 4.13Å; Y240-F504 HydrophobicContact CD1-CZ 4.22Å; Y240-F504 AromaticContact CE1-CE1 3.77Å; Y240-F504 HydrophobicContact CE1-CE1 3.77Å; Y240-F504 AromaticContact CE1-CZ 3.67Å; Y240-F504 HydrophobicContact CE1-CZ 3.67Å; V350-F504 HydrophobicContact CG1-CD2 4.22Å; V350-F504 HydrophobicContact CG1-CE2 4.33Å; G500-F504 CarbonylContact C-O 3.05Å; G500-F504 WeakPolarHBondContact CA-O 3.19Å; S501-F504 PolarHBondContact N-O 3.35Å; S501-F504 CarbonylContact O-C 3.3Å; S501-F504 VanDerWaalsContact O-C 3.25Å; S501-F504 PolarHBondContact O-N 3.08Å; S501-F504 VanDerWaalsContact O-O 3.09Å; S501-F504 WeakPolarHBondContact OG-CD2 3.45Å; S501-F504 PolarHBondContact OG-N 3.46Å; F504-S506 PolarHBondContact O-N 2.86Å
505	P	71.9	Confident	75.5	Confident	106 Å²	106	76.8 Å²	76.8	69%	0.688	42%	0.417	S	S	*	.			trans	-58.7	143.3	179.8	24.8	-33.4	0	0	0	110.4	I503 Q507	I503-P505 WeakPolarHBondContact O-CD 3.47Å; P505-Q507 PolarHBondContact O-N 3.28Å
506	S	74.4	Confident	75.9	Confident	61 Å²	61	75.7 Å²	75.7	43%	0.427	41%	0.413	S	S	.	.			trans	-65.4	137.8	179.4	60.8	0	0	0	0	110.5	G498 F504 C508	G498-S506 WeakPolarHBondContact O-CB 3.31Å; F504-S506 PolarHBondContact O-N 2.86Å; S506-C508 VanDerWaalsContact C-N 3.26Å
507	Q	74.8	Confident	76.3	Confident	163 Å²	163	66.3 Å²	66.3	76%	0.762	38%	0.377	S	S	*	.			trans	-89.9	4.9	173.3	-64.9	-174.4	-7.7	0	0	112.1	P505	P505-Q507 PolarHBondContact O-N 3.28Å
508	C	78	Confident	76.9	Confident	14 Å²	14	62 Å²	62	10%	0.095	36%	0.358	C	S	.	.	S	Bend	trans	-71	133.7	-175.5	-172.7	0	0	0	0	111.1	F497 S506 F510 C513	F497-C508 HydrophobicContact CB-CB 3.87Å; F497-C508 HydrophobicContact CD2-CB 4.45Å; F497-C508 HydrophobicContact CG-CB 4.43Å; S506-C508 VanDerWaalsContact C-N 3.26Å; C508-F510 PolarHBondContact O-N 3.31Å; C508-C513 HydrophobicContact CB-CB 3.45Å; C508-C513 VanDerWaalsContact CB-CB 3.45Å; C508-C513 WeakPolarHBondContact CB-SG 3.4Å; C508-C513 WeakPolarHBondContact SG-CB 3.23Å; C508-C513 CovalentContact SG-SG 2.02Å; C508-C513 PolarHBondContact SG-SG 2.9Å
509	P	79.7	Confident	78	Confident	66 Å²	66	62.5 Å²	62.5	43%	0.429	35%	0.352	S	S	.	.			trans	-54.8	135.4	177.7	-26.6	34	0	0	0	112.9	L511 V512 C513	P509-L511 PolarHBondContact O-N 3.05Å; P509-L511 VanDerWaalsContact O-N 3.15Å; P509-V512 PolarHBondContact O-N 3.49Å; P509-C513 PolarHBondContact O-N 2.64Å
510	F	76.3	Confident	79.3	Confident	175 Å²	175	61.8 Å²	61.8	77%	0.768	35%	0.345	S	S	*	.	H	α-helix	trans	-55.5	-35.1	-179	-178.5	-97.6	0	0	0	113.2	C508 V512 G514	C508-F510 PolarHBondContact O-N 3.31Å; F510-V512 PolarHBondContact O-N 3.41Å; F510-G514 WeakPolarHBondContact O-CA 3.34Å; F510-G514 PolarHBondContact O-N 2.87Å
511	L	73.2	Confident	80.6	Confident	161 Å²	161	60.9 Å²	60.9	84%	0.843	34%	0.336	S	S	*	.	H	α-helix	trans	-61.9	-30.6	177.9	-171.4	68.5	0	0	0	112.8	P509	P509-L511 PolarHBondContact O-N 3.05Å; P509-L511 VanDerWaalsContact O-N 3.15Å
512	V	75.9	Confident	81.7	Confident	53 Å²	53	62 Å²	62	32%	0.321	34%	0.34	S	S	.	.	H	α-helix	trans	-96.6	-50	-177.4	-175.9	0	0	0	0	110.5	R490 P493 P509 F510	R490-V512 WeakPolarHBondContact CD-O 3.44Å; R490-V512 PolarHBondContact NE-O 3.38Å; R490-V512 VanDerWaalsContact NE-O 3.08Å; P493-V512 HydrophobicContact CB-CG1 3.85Å; P493-V512 HydrophobicContact CG-CG1 3.91Å; P509-V512 PolarHBondContact O-N 3.49Å; F510-V512 PolarHBondContact O-N 3.41Å
513	C	76.5	Confident	82.8	Confident	22 Å²	22	61.1 Å²	61.1	15%	0.149	33%	0.328	C	S	.	.	H	α-helix	trans	-105.2	-6.6	-173.2	-64.5	0	0	0	0	115.5	R490 C508 P509 I515	R490-C513 PolarHBondContact NH2-O 3.37Å; C508-C513 HydrophobicContact CB-CB 3.45Å; C508-C513 VanDerWaalsContact CB-CB 3.45Å; C508-C513 WeakPolarHBondContact CB-SG 3.4Å; C508-C513 WeakPolarHBondContact SG-CB 3.23Å; C508-C513 CovalentContact SG-SG 2.02Å; C508-C513 PolarHBondContact SG-SG 2.9Å; P509-C513 PolarHBondContact O-N 2.64Å; C513-I515 PolarHBondContact O-N 3.12Å
514	G	78.9	Confident	84	Confident	35 Å²	35	60.5 Å²	60.5	36%	0.361	33%	0.325	S	S	.	.			trans	-70.8	-15.8	-175.6	0	0	0	0	0	114.5	F510	F510-G514 WeakPolarHBondContact O-CA 3.34Å; F510-G514 PolarHBondContact O-N 2.87Å
515	I	87.4	Confident	85.1	Confident	72 Å²	72	58 Å²	58	37%	0.369	31%	0.314	S	S	.	.	S	Bend	trans	-85.5	124.4	174.7	-56.6	175	0	0	0	109.2	R490 C513 H519 F520 I523	R490-I515 PolarHBondContact NH2-O 2.9Å; C513-I515 PolarHBondContact O-N 3.12Å; I515-H519 HydrophobicContact CG2-CB 3.84Å; I515-F520 HydrophobicContact CG2-CB 4.24Å; I515-I523 HydrophobicContact CD1-CD1 4.29Å; I515-I523 HydrophobicContact CG2-CD1 4.39Å
516	H	90.1	Very high	86.3	Confident	47 Å²	47	56.3 Å²	56.3	22%	0.218	30%	0.302	C	S	.	.			trans	-56.1	139.4	174.7	-171.6	-92	0	0	0	111.9	D264 P266 L518 H519 F520	D264-H516 PolarHBondContact O-CE1 3.26Å; D264-H516 PolarHBondContact O-NE2 3.13Å; P266-H516 HydrophobicContact CG-CB 4.4Å; H516-L518 VanDerWaalsContact C-N 3.27Å; H516-L518 PolarHBondContact ND1-N 3.43Å; H516-L518 PolarHBondContact O-N 2.94Å; H516-L518 VanDerWaalsContact O-N 3.14Å; H516-H519 WeakPolarHBondContact O-CB 3.19Å; H516-H519 PolarHBondContact O-N 3.45Å; H516-F520 PolarHBondContact O-N 3.12Å
517	Y	90.9	Very high	87.4	Confident	18 Å²	18	55.7 Å²	55.7	7%	0.071	30%	0.297	C	S	.	.	H	α-helix	trans	-57.5	-34.9	-171.6	67.2	-96.8	0	0	0	113.7	L265 Q448 S452 Y453 F520 A521	L265-Y517 WeakPolarHBondContact CD2-OH 3.4Å; Q448-Y517 HydrophobicContact CB-CE2 3.81Å; S452-Y517 WeakPolarHBondContact OG-CD2 3.45Å; Y453-Y517 WeakPolarHBondContact OH-CB 3.48Å; Y517-F520 PolarHBondContact O-N 3.41Å; Y517-A521 PolarHBondContact O-N 3.27Å
518	L	92.4	Very high	88.5	Confident	1 Å²	1	48 Å²	48	1%	0.005	26%	0.261	C	S	.	.	H	α-helix	trans	-68.3	-36.5	175.7	-66.7	174	0	0	0	113	F89 L265 M274 H516 A521 I522	F89-L518 HydrophobicContact CZ-CD2 4.4Å; L265-L518 HydrophobicContact CD2-CD1 4.16Å; M274-L518 HydrophobicContact CG-CD1 4.25Å; M274-L518 HydrophobicContact CG-CD2 3.89Å; H516-L518 VanDerWaalsContact C-N 3.27Å; H516-L518 PolarHBondContact ND1-N 3.43Å; H516-L518 PolarHBondContact O-N 2.94Å; H516-L518 VanDerWaalsContact O-N 3.14Å; L518-A521 WeakPolarHBondContact O-CB 3.48Å; L518-A521 PolarHBondContact O-N 3.48Å; L518-I522 WeakPolarHBondContact O-CG1 3.23Å; L518-I522 PolarHBondContact O-N 3.11Å
519	H	93.4	Very high	89.4	Confident	43 Å²	43	48.1 Å²	48.1	20%	0.199	26%	0.262	C	S	.	.	H	α-helix	trans	-70.5	-40.1	174.1	-68.4	118	0	0	0	110.6	P260 P266 I515 H516 A521 I522 I523	P260-H519 PolarHBondContact O-CE1 3.22Å; P260-H519 VanDerWaalsContact O-CE1 3.24Å; P266-H519 WeakPolarHBondContact CG-CE1 3.32Å; I515-H519 HydrophobicContact CG2-CB 3.84Å; H516-H519 WeakPolarHBondContact O-CB 3.19Å; H516-H519 PolarHBondContact O-N 3.45Å; H519-A521 VanDerWaalsContact C-N 3.26Å; H519-A521 PolarHBondContact O-N 3.42Å; H519-I522 WeakPolarHBondContact O-CB 3.43Å; H519-I522 PolarHBondContact O-N 3.09Å; H519-I522 VanDerWaalsContact O-N 3.11Å; H519-I523 WeakPolarHBondContact O-CG1 3.48Å; H519-I523 PolarHBondContact O-N 3.06Å; H519-I523 VanDerWaalsContact O-N 3.07Å
520	F	93.4	Very high	90.2	Very high	28 Å²	28	48.4 Å²	48.4	12%	0.123	26%	0.262	C	S	.	.	H	α-helix	trans	-59.6	-38.3	173.7	-173	-94.5	0	0	0	111.7	Y453 R490 I515 H516 Y517 I522 I523 L524	Y453-F520 AromaticContact CD1-CD1 3.63Å; Y453-F520 HydrophobicContact CD1-CD1 3.63Å; Y453-F520 AromaticContact CD1-CE1 3.95Å; Y453-F520 HydrophobicContact CD1-CE1 3.95Å; Y453-F520 HydrophobicContact CE1-CD1 4.03Å; R490-F520 HydrophobicContact CB-CD1 4.38Å; R490-F520 HydrophobicContact CB-CD2 4.42Å; R490-F520 HydrophobicContact CB-CE1 3.7Å; R490-F520 HydrophobicContact CB-CE2 3.77Å; R490-F520 HydrophobicContact CB-CZ 3.36Å; R490-F520 HydrophobicContact CG-CD1 4.07Å; R490-F520 HydrophobicContact CG-CD2 4.11Å; R490-F520 HydrophobicContact CG-CE1 3.9Å; R490-F520 HydrophobicContact CG-CE2 3.97Å; R490-F520 HydrophobicContact CG-CG 4.16Å; R490-F520 HydrophobicContact CG-CZ 3.86Å; I515-F520 HydrophobicContact CG2-CB 4.24Å; H516-F520 PolarHBondContact O-N 3.12Å; Y517-F520 PolarHBondContact O-N 3.41Å; F520-I522 VanDerWaalsContact C-N 3.31Å; F520-I522 PolarHBondContact O-N 3.46Å; F520-I523 PolarHBondContact O-N 3.01Å; F520-L524 HydrophobicContact CD1-CB 4.45Å; F520-L524 HydrophobicContact CE1-CB 4.25Å; F520-L524 HydrophobicContact CE1-CD2 4.02Å; F520-L524 VanDerWaalsContact O-CB 3.23Å; F520-L524 WeakPolarHBondContact O-CB 3.4Å; F520-L524 PolarHBondContact O-N 3.23Å
521	A	95.1	Very high	91.2	Very high	1 Å²	1	42.9 Å²	42.9	1%	0.008	24%	0.24	C	C	.	.	H	α-helix	trans	-59	-40	174.3	0	0	0	0	0	112.8	P456 Y517 L518 H519 F525	P456-A521 HydrophobicContact CG-CB 3.88Å; Y517-A521 PolarHBondContact O-N 3.27Å; L518-A521 WeakPolarHBondContact O-CB 3.48Å; L518-A521 PolarHBondContact O-N 3.48Å; H519-A521 VanDerWaalsContact C-N 3.26Å; H519-A521 PolarHBondContact O-N 3.42Å; A521-F525 VanDerWaalsContact O-CB 3.25Å; A521-F525 WeakPolarHBondContact O-CB 3.4Å; A521-F525 PolarHBondContact O-N 3.44Å
522	I	95.9	Very high	92.3	Very high	43 Å²	43	35.2 Å²	35.2	22%	0.221	20%	0.2	C	C	.	.	H	α-helix	trans	-64.5	-47.4	176.3	-59.4	164.8	0	0	0	110.4	F272 I276 L518 H519 F520 F525 T526	F272-I522 HydrophobicContact CB-CD1 3.67Å; F272-I522 HydrophobicContact CB-CG1 4Å; I276-I522 HydrophobicContact CD1-CB 4.36Å; I276-I522 HydrophobicContact CD1-CG1 4.09Å; L518-I522 WeakPolarHBondContact O-CG1 3.23Å; L518-I522 PolarHBondContact O-N 3.11Å; H519-I522 WeakPolarHBondContact O-CB 3.43Å; H519-I522 PolarHBondContact O-N 3.09Å; H519-I522 VanDerWaalsContact O-N 3.11Å; F520-I522 VanDerWaalsContact C-N 3.31Å; F520-I522 PolarHBondContact O-N 3.46Å; I522-F525 PolarHBondContact O-N 3.05Å; I522-T526 WeakPolarHBondContact O-CB 3.46Å; I522-T526 PolarHBondContact O-N 2.71Å; I522-T526 PolarHBondContact O-OG1 2.92Å
523	I	95.6	Very high	93.2	Very high	76 Å²	76	35.1 Å²	35.1	39%	0.39	20%	0.198	S	C	.	.	H	α-helix	trans	-60.3	-49.4	178.2	-64.9	167.4	0	0	0	109.5	I515 H519 F520 F525 T526 C527	I515-I523 HydrophobicContact CD1-CD1 4.29Å; I515-I523 HydrophobicContact CG2-CD1 4.39Å; H519-I523 WeakPolarHBondContact O-CG1 3.48Å; H519-I523 PolarHBondContact O-N 3.06Å; H519-I523 VanDerWaalsContact O-N 3.07Å; F520-I523 PolarHBondContact O-N 3.01Å; I523-F525 PolarHBondContact O-N 2.85Å; I523-T526 PolarHBondContact O-N 2.9Å; I523-C527 WeakPolarHBondContact O-CB 3.11Å; I523-C527 PolarHBondContact O-N 3.43Å; I523-C527 PolarHBondContact O-SG 3.36Å
524	L	96.4	Very high	94.1	Very high	2 Å²	2	39 Å²	39	1%	0.01	22%	0.216	C	C	.	.	H	α-helix	trans	-61.8	-44.5	-177.7	-176.5	59.9	0	0	0	112	Y453 P456 P457 G483 M486 F520 T528	Y453-L524 WeakPolarHBondContact O-CD2 3.23Å; P456-L524 HydrophobicContact CB-CB 4.25Å; P456-L524 HydrophobicContact CB-CD2 4.13Å; P456-L524 HydrophobicContact CB-CG 4.13Å; P456-L524 HydrophobicContact CG-CD2 4.03Å; P456-L524 HydrophobicContact CG-CG 4.49Å; P457-L524 HydrophobicContact CG-CD1 4.26Å; P457-L524 HydrophobicContact CG-CD2 4Å; P457-L524 HydrophobicContact CG-CG 4Å; G483-L524 WeakPolarHBondContact O-CD1 3.49Å; M486-L524 HydrophobicContact CB-CD1 3.61Å; M486-L524 HydrophobicContact CE-CD1 4Å; F520-L524 HydrophobicContact CD1-CB 4.45Å; F520-L524 HydrophobicContact CE1-CB 4.25Å; F520-L524 HydrophobicContact CE1-CD2 4.02Å; F520-L524 VanDerWaalsContact O-CB 3.23Å; F520-L524 WeakPolarHBondContact O-CB 3.4Å; F520-L524 PolarHBondContact O-N 3.23Å; L524-T528 VanDerWaalsContact O-CB 3.25Å; L524-T528 WeakPolarHBondContact O-CB 3.32Å; L524-T528 PolarHBondContact O-N 3.44Å; L524-T528 PolarHBondContact O-OG1 3.05Å
525	F	97.3	Very high	94.9	Very high	31 Å²	31	39.2 Å²	39.2	14%	0.136	21%	0.211	C	C	.	.	H	α-helix	trans	-58.9	-48.7	174.5	178.9	-94.2	0	0	0	111.5	I276 P456 A459 L463 A521 I522 I523 T528 S529	I276-F525 HydrophobicContact CD1-CB 3.72Å; I276-F525 HydrophobicContact CD1-CD1 4.05Å; I276-F525 HydrophobicContact CD1-CD2 4.42Å; I276-F525 HydrophobicContact CD1-CG 3.82Å; I276-F525 HydrophobicContact CG1-CB 4.31Å; I276-F525 HydrophobicContact CG1-CD1 4.33Å; I276-F525 HydrophobicContact CG1-CD2 4.12Å; I276-F525 HydrophobicContact CG1-CG 4Å; I276-F525 HydrophobicContact CG2-CB 3.97Å; I276-F525 HydrophobicContact CG2-CD2 3.63Å; I276-F525 HydrophobicContact CG2-CE2 4.42Å; I276-F525 HydrophobicContact CG2-CG 4.01Å; P456-F525 HydrophobicContact CB-CB 4.03Å; A459-F525 HydrophobicContact CB-CD2 4.31Å; A459-F525 HydrophobicContact CB-CE2 4.25Å; L463-F525 HydrophobicContact CD2-CE2 4.48Å; L463-F525 HydrophobicContact CD2-CZ 3.78Å; A521-F525 VanDerWaalsContact O-CB 3.25Å; A521-F525 WeakPolarHBondContact O-CB 3.4Å; A521-F525 PolarHBondContact O-N 3.44Å; I522-F525 PolarHBondContact O-N 3.05Å; I523-F525 PolarHBondContact O-N 2.85Å; F525-T528 PolarHBondContact O-N 2.99Å; F525-S529 WeakPolarHBondContact O-CB 3.42Å; F525-S529 PolarHBondContact O-N 3.42Å; F525-S529 PolarHBondContact O-OG 3.45Å
526	T	97.3	Very high	95.2	Very high	70 Å²	70	35.8 Å²	35.8	43%	0.429	19%	0.193	S	C	.	.	H	α-helix	trans	-66.3	-49.6	-176.2	-54.6	0	0	0	0	111	I522 I523 T528 S529 V530	I522-T526 WeakPolarHBondContact O-CB 3.46Å; I522-T526 PolarHBondContact O-N 2.71Å; I522-T526 PolarHBondContact O-OG1 2.92Å; I523-T526 PolarHBondContact O-N 2.9Å; T526-T528 VanDerWaalsContact C-N 3.3Å; T526-T528 PolarHBondContact O-N 3.48Å; T526-S529 PolarHBondContact O-N 3.37Å; T526-V530 WeakPolarHBondContact O-CG2 3.07Å; T526-V530 PolarHBondContact O-N 3.4Å
527	C	97.2	Very high	95.2	Very high	49 Å²	49	39.4 Å²	39.4	33%	0.331	21%	0.209	S	C	.	.	H	α-helix	trans	-57.9	-44	175.7	-69.7	0	0	0	0	111.1	M486 I523 V530 L531	M486-C527 HydrophobicContact CE-CB 3.9Å; M486-C527 HydrophobicContact SD-CB 4Å; I523-C527 WeakPolarHBondContact O-CB 3.11Å; I523-C527 PolarHBondContact O-N 3.43Å; I523-C527 PolarHBondContact O-SG 3.36Å; C527-V530 PolarHBondContact O-N 3.46Å; C527-L531 WeakPolarHBondContact O-CB 3.19Å; C527-L531 VanDerWaalsContact O-CG 3.28Å; C527-L531 WeakPolarHBondContact O-CG 3.41Å; C527-L531 PolarHBondContact O-N 3.36Å
528	T	97.4	Very high	95.4	Very high	0 Å²	0	44 Å²	44	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-64.5	-45.6	176.9	-55.7	0	0	0	0	111.5	P457 G479 L524 F525 T526 V530 L531 V532	P457-T528 HydrophobicContact CB-CG2 4.01Å; G479-T528 WeakPolarHBondContact O-CG2 3.24Å; L524-T528 VanDerWaalsContact O-CB 3.25Å; L524-T528 WeakPolarHBondContact O-CB 3.32Å; L524-T528 PolarHBondContact O-N 3.44Å; L524-T528 PolarHBondContact O-OG1 3.05Å; F525-T528 PolarHBondContact O-N 2.99Å; T526-T528 VanDerWaalsContact C-N 3.3Å; T526-T528 PolarHBondContact O-N 3.48Å; T528-V530 VanDerWaalsContact C-N 3.34Å; T528-V530 PolarHBondContact O-N 3.43Å; T528-L531 PolarHBondContact O-N 2.94Å; T528-V532 HydrophobicContact CG2-CG2 4.18Å; T528-V532 VanDerWaalsContact O-CG2 3.22Å; T528-V532 WeakPolarHBondContact O-CG2 3.45Å; T528-V532 PolarHBondContact O-N 3.33Å
529	S	97.1	Very high	95.3	Very high	17 Å²	17	46 Å²	46	12%	0.119	26%	0.255	C	S	.	.	H	α-helix	trans	-57.6	-46.1	176.9	-82	0	0	0	0	111.9	S460 F525 T526 V532 L533	S460-S529 VanDerWaalsContact OG-CA 3.28Å; S460-S529 WeakPolarHBondContact OG-CA 3.47Å; S460-S529 PolarHBondContact OG-N 3.34Å; S460-S529 PolarHBondContact OG-OG 3.09Å; F525-S529 WeakPolarHBondContact O-CB 3.42Å; F525-S529 PolarHBondContact O-N 3.42Å; F525-S529 PolarHBondContact O-OG 3.45Å; T526-S529 PolarHBondContact O-N 3.37Å; S529-V532 PolarHBondContact O-N 2.87Å; S529-L533 WeakPolarHBondContact O-CB 3.43Å; S529-L533 VanDerWaalsContact O-CG 3.26Å; S529-L533 WeakPolarHBondContact O-CG 3.06Å; S529-L533 PolarHBondContact O-N 3.28Å
530	V	97.3	Very high	94.8	Very high	73 Å²	73	52 Å²	52	44%	0.442	28%	0.283	S	S	.	.	H	α-helix	trans	-62.5	-46.7	177.6	171	0	0	0	0	110.6	T526 C527 T528 V532 L533 L534	T526-V530 WeakPolarHBondContact O-CG2 3.07Å; T526-V530 PolarHBondContact O-N 3.4Å; C527-V530 PolarHBondContact O-N 3.46Å; T528-V530 VanDerWaalsContact C-N 3.34Å; T528-V530 PolarHBondContact O-N 3.43Å; V530-V532 PolarHBondContact O-N 3.06Å; V530-L533 PolarHBondContact O-N 3.47Å; V530-L534 HydrophobicContact CG1-CD1 3.63Å; V530-L534 HydrophobicContact CG1-CG 4.07Å; V530-L534 WeakPolarHBondContact O-CB 3.34Å; V530-L534 VanDerWaalsContact O-CG 3.27Å; V530-L534 WeakPolarHBondContact O-CG 3.06Å; V530-L534 PolarHBondContact O-N 2.92Å
531	L	96.8	Very high	94.2	Very high	58 Å²	58	55.1 Å²	55.1	30%	0.304	31%	0.306	S	S	.	.	H	α-helix	trans	-60.6	-46.1	177.6	-74.6	171.1	0	0	0	112.3	C482 M486 C527 T528 L533 L534 V535	C482-L531 HydrophobicContact CB-CD1 3.85Å; M486-L531 HydrophobicContact CE-CD1 4Å; C527-L531 WeakPolarHBondContact O-CB 3.19Å; C527-L531 VanDerWaalsContact O-CG 3.28Å; C527-L531 WeakPolarHBondContact O-CG 3.41Å; C527-L531 PolarHBondContact O-N 3.36Å; T528-L531 PolarHBondContact O-N 2.94Å; L531-L533 VanDerWaalsContact C-N 3.31Å; L531-L533 PolarHBondContact O-N 2.91Å; L531-L534 PolarHBondContact O-N 2.94Å; L531-V535 WeakPolarHBondContact O-CB 3.03Å; L531-V535 VanDerWaalsContact O-CG2 3.32Å; L531-V535 WeakPolarHBondContact O-CG2 3.31Å; L531-V535 PolarHBondContact O-N 2.87Å
532	V	96.1	Very high	93.4	Very high	0 Å²	0	56.5 Å²	56.5	0%	0	31%	0.313	C	S	.	.	H	α-helix	trans	-57.3	-48.1	176.8	172.1	0	0	0	0	110.1	V461 L464 V471 T528 S529 V530 S536	V461-V532 HydrophobicContact CG2-CG2 3.95Å; L464-V532 HydrophobicContact CD1-CB 3.84Å; L464-V532 HydrophobicContact CD1-CG1 3.68Å; L464-V532 HydrophobicContact CD1-CG2 4.45Å; V471-V532 HydrophobicContact CG1-CG1 3.58Å; V471-V532 HydrophobicContact CG2-CG1 4.16Å; T528-V532 HydrophobicContact CG2-CG2 4.18Å; T528-V532 VanDerWaalsContact O-CG2 3.22Å; T528-V532 WeakPolarHBondContact O-CG2 3.45Å; T528-V532 PolarHBondContact O-N 3.33Å; S529-V532 PolarHBondContact O-N 2.87Å; V530-V532 PolarHBondContact O-N 3.06Å; V532-S536 WeakPolarHBondContact O-CB 3.4Å; V532-S536 PolarHBondContact O-N 3.26Å; V532-S536 PolarHBondContact O-OG 3.18Å; V532-S536 VanDerWaalsContact O-OG 3.08Å
533	L	95.3	Very high	92.1	Very high	52 Å²	52	60.9 Å²	60.9	27%	0.272	33%	0.332	S	S	.	.	H	α-helix	trans	-64.2	-52.5	179.8	-69.2	172.2	0	0	0	111.3	L464 V468 V471 S529 V530 L531 V535 S536 F537	L464-L533 HydrophobicContact CD1-CG 4.42Å; L464-L533 HydrophobicContact CD2-CD2 4.15Å; L464-L533 HydrophobicContact CD2-CG 4.4Å; V468-L533 HydrophobicContact CG1-CD2 4.14Å; V471-L533 HydrophobicContact CG2-CD2 3.96Å; S529-L533 WeakPolarHBondContact O-CB 3.43Å; S529-L533 VanDerWaalsContact O-CG 3.26Å; S529-L533 WeakPolarHBondContact O-CG 3.06Å; S529-L533 PolarHBondContact O-N 3.28Å; V530-L533 PolarHBondContact O-N 3.47Å; L531-L533 VanDerWaalsContact C-N 3.31Å; L531-L533 PolarHBondContact O-N 2.91Å; L533-V535 PolarHBondContact O-N 3.35Å; L533-S536 PolarHBondContact O-N 3.33Å; L533-F537 HydrophobicContact CB-CD2 4.3Å; L533-F537 HydrophobicContact CB-CE2 4.37Å; L533-F537 HydrophobicContact CD2-CE2 4.12Å; L533-F537 WeakPolarHBondContact O-CB 3.27Å; L533-F537 WeakPolarHBondContact O-CD2 3.25Å; L533-F537 PolarHBondContact O-N 3.29Å
534	L	95.5	Very high	90.5	Very high	102 Å²	102	61.6 Å²	61.6	53%	0.534	34%	0.337	S	S	.	.	H	α-helix	trans	-55.6	-52	-179	-72.9	175.6	0	0	0	111.6	V530 L531 S536 F537 C538	V530-L534 HydrophobicContact CG1-CD1 3.63Å; V530-L534 HydrophobicContact CG1-CG 4.07Å; V530-L534 WeakPolarHBondContact O-CB 3.34Å; V530-L534 VanDerWaalsContact O-CG 3.27Å; V530-L534 WeakPolarHBondContact O-CG 3.06Å; V530-L534 PolarHBondContact O-N 2.92Å; L531-L534 PolarHBondContact O-N 2.94Å; L534-S536 VanDerWaalsContact C-N 3.34Å; L534-S536 PolarHBondContact O-N 2.94Å; L534-F537 PolarHBondContact O-N 3.43Å; L534-C538 WeakPolarHBondContact O-CB 3.31Å; L534-C538 PolarHBondContact O-N 3.25Å; L534-C538 PolarHBondContact O-SG 3.01Å
535	V	94.9	Very high	88.7	Confident	40 Å²	40	70.4 Å²	70.4	24%	0.242	38%	0.375	C	S	.	.	H	α-helix	trans	-63.4	-42.9	179.5	177.1	0	0	0	0	110.4	T474 L531 L533 F537 C538 T539	T474-V535 HydrophobicContact CG2-CG1 4.21Å; L531-V535 WeakPolarHBondContact O-CB 3.03Å; L531-V535 VanDerWaalsContact O-CG2 3.32Å; L531-V535 WeakPolarHBondContact O-CG2 3.31Å; L531-V535 PolarHBondContact O-N 2.87Å; L533-V535 PolarHBondContact O-N 3.35Å; V535-F537 PolarHBondContact O-N 3.47Å; V535-C538 PolarHBondContact O-N 3.47Å; V535-T539 HydrophobicContact CG1-CG2 4.27Å; V535-T539 WeakPolarHBondContact O-CB 3.49Å; V535-T539 WeakPolarHBondContact O-CG2 3.38Å; V535-T539 PolarHBondContact O-N 3.35Å; V535-T539 VanDerWaalsContact O-N 3.07Å; V535-T539 PolarHBondContact O-OG1 3.42Å
536	S	93	Very high	86.7	Confident	1 Å²	1	72.2 Å²	72.2	1%	0.007	38%	0.384	C	S	.	.	H	α-helix	trans	-64.9	-34.7	177.7	-75.1	0	0	0	0	113.9	R470 V471 N472 V532 L533 L534	R470-S536 PolarHBondContact NH1-O 2.9Å; R470-S536 PolarHBondContact NH2-O 2.85Å; V471-S536 WeakPolarHBondContact CA-OG 3.3Å; N472-S536 PolarHBondContact N-OG 3.22Å; N472-S536 WeakPolarHBondContact OD1-CA 3.28Å; N472-S536 WeakPolarHBondContact OD1-CB 3.35Å; N472-S536 PolarHBondContact OD1-OG 3.42Å; V532-S536 WeakPolarHBondContact O-CB 3.4Å; V532-S536 PolarHBondContact O-N 3.26Å; V532-S536 PolarHBondContact O-OG 3.18Å; V532-S536 VanDerWaalsContact O-OG 3.08Å; L533-S536 PolarHBondContact O-N 3.33Å; L534-S536 VanDerWaalsContact C-N 3.34Å; L534-S536 PolarHBondContact O-N 2.94Å
537	F	91.9	Very high	84.7	Confident	123 Å²	123	69.1 Å²	69.1	54%	0.539	37%	0.365	S	S	.	.	H	α-helix	trans	-73.7	-34.2	176.5	-83	-74.6	0	0	0	112.3	R470 L533 L534 V535	R470-F537 HydrophobicContact CB-CE1 4.24Å; R470-F537 HydrophobicContact CB-CZ 4.23Å; R470-F537 HydrophobicContact CG-CD1 3.77Å; R470-F537 HydrophobicContact CG-CE1 3.59Å; R470-F537 HydrophobicContact CG-CG 4.34Å; R470-F537 HydrophobicContact CG-CZ 3.98Å; R470-F537 PolarHBondContact NH2-O 2.95Å; L533-F537 HydrophobicContact CB-CD2 4.3Å; L533-F537 HydrophobicContact CB-CE2 4.37Å; L533-F537 HydrophobicContact CD2-CE2 4.12Å; L533-F537 WeakPolarHBondContact O-CB 3.27Å; L533-F537 WeakPolarHBondContact O-CD2 3.25Å; L533-F537 PolarHBondContact O-N 3.29Å; L534-F537 PolarHBondContact O-N 3.43Å; V535-F537 PolarHBondContact O-N 3.47Å
538	C	93.3	Very high	82.5	Confident	114 Å²	114	70 Å²	70	77%	0.77	37%	0.371	S	S	*	.	H	α-helix	trans	-80.6	-10.9	178.2	-65.7	0	0	0	0	114.4	L534 V535	L534-C538 WeakPolarHBondContact O-CB 3.31Å; L534-C538 PolarHBondContact O-N 3.25Å; L534-C538 PolarHBondContact O-SG 3.01Å; V535-C538 PolarHBondContact O-N 3.47Å
539	T	90.5	Very high	79.9	Confident	44 Å²	44	77.7 Å²	77.7	27%	0.27	41%	0.407	S	S	.	.	S	Bend	trans	-113.1	168.1	-179.4	50.8	0	0	0	0	111.6	R470 N472 T474 V535	R470-T539 PolarHBondContact NH1-O 3.22Å; R470-T539 PolarHBondContact NH2-O 3.29Å; N472-T539 PolarHBondContact ND2-OG1 3.49Å; T474-T539 HydrophobicContact CG2-CG2 4.27Å; V535-T539 HydrophobicContact CG1-CG2 4.27Å; V535-T539 WeakPolarHBondContact O-CB 3.49Å; V535-T539 WeakPolarHBondContact O-CG2 3.38Å; V535-T539 PolarHBondContact O-N 3.35Å; V535-T539 VanDerWaalsContact O-N 3.07Å; V535-T539 PolarHBondContact O-OG1 3.42Å
540	E	84.4	Confident	77.4	Confident	169 Å²	169	84.7 Å²	84.7	79%	0.79	43%	0.431	S	S	*	.	P	Polyproline II helix	trans	-56.1	142.3	-174	-68.2	-178.1	173.4	0	0	113.1	R470 N472	R470-E540 PolarHBondContact NH1-O 2.72Å; N472-E540 PolarHBondContact ND2-O 3.22Å
541	P	80.6	Confident	75.1	Confident	93 Å²	93	82.4 Å²	82.4	60%	0.604	42%	0.415	S	S	*	.	P	Polyproline II helix	trans	-65.9	148.1	176.3	29	-33.6	0	0	0	111.7	E543	P541-E543 PolarHBondContact O-N 3Å
542	I	77.3	Confident	72.8	Confident	30 Å²	30	82.9 Å²	82.9	15%	0.154	42%	0.415	C	S	.	.	P	Polyproline II helix	trans	-62.8	132.8	175	-61.1	164.4	0	0	0	109.6	F124 V471 N472 D544 H546 V547	F124-I542 HydrophobicContact CD1-CD1 4.21Å; V471-I542 WeakPolarHBondContact O-CD1 3.18Å; N472-I542 HydrophobicContact CB-CD1 4.19Å; N472-I542 HydrophobicContact CB-CG1 3.55Å; I542-D544 PolarHBondContact O-N 3.35Å; I542-H546 HydrophobicContact CG2-CB 3.78Å; I542-V547 HydrophobicContact CG2-CG2 4.48Å
543	E	69.4	Low	70.3	Confident	134 Å²	134	84.1 Å²	84.1	63%	0.626	43%	0.427	S	S	*	.	P	Polyproline II helix	trans	-53.1	132.9	167.1	-66	-177.9	171.8	0	0	111.6	P541 K545 H546	P541-E543 PolarHBondContact O-N 3Å; E543-K545 PolarHBondContact O-N 3.44Å; E543-H546 PolarHBondContact O-N 3.07Å
544	D	62.3	Low	68	Low	92 Å²	92	86.3 Å²	86.3	49%	0.492	43%	0.432	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.9	-8	-176.3	-87	-41.6	0	0	0	114.6	K469 I542 K552	K469-D544 IonicContact NZ-OD1 2.78Å; K469-D544 PolarHBondContact NZ-OD1 3.1Å; K469-D544 VanDerWaalsContact NZ-OD1 3.14Å; I542-D544 PolarHBondContact O-N 3.35Å; D544-K552 PolarHBondContact O-NZ 3.16Å
545	K	58.8	Low	65.7	Low	186 Å²	186	83.6 Å²	83.6	81%	0.809	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72	-30.8	174.7	-163.5	176.9	-176.5	179.6	0	113.3	E543	E543-K545 PolarHBondContact O-N 3.44Å
546	H	55.4	Low	62.9	Low	69 Å²	69	90.6 Å²	90.6	32%	0.319	44%	0.442	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.9	-12.7	178.4	-62.3	123.3	0	0	0	113.1	I542 E543 S548	I542-H546 HydrophobicContact CG2-CB 3.78Å; E543-H546 PolarHBondContact O-N 3.07Å; H546-S548 PolarHBondContact O-N 3.3Å
547	V	55.3	Low	60.4	Low	5 Å²	5	95 Å²	95	3%	0.03	47%	0.465	C	S	.	.	S	Bend	trans	-82.1	104.9	169.5	-176	0	0	0	0	107.3	I542 E549 F551 K552	I542-V547 HydrophobicContact CG2-CG2 4.48Å; V547-E549 PolarHBondContact O-N 2.77Å; V547-F551 HydrophobicContact CG1-CB 4.09Å; V547-F551 HydrophobicContact CG1-CD1 3.55Å; V547-F551 HydrophobicContact CG1-CE1 4.41Å; V547-F551 HydrophobicContact CG1-CG 4.16Å; V547-K552 HydrophobicContact CG1-CG 3.98Å
548	S	49.7	Very low	58	Low	67 Å²	67	93.6 Å²	93.6	47%	0.469	46%	0.46	S	S	.	.			trans	-51.4	137.9	-179.5	76.3	0	0	0	0	110.8	H546 R550 F551 K552	H546-S548 PolarHBondContact O-N 3.3Å; S548-R550 PolarHBondContact O-N 3.5Å; S548-F551 WeakPolarHBondContact O-CB 3.34Å; S548-F551 PolarHBondContact O-N 2.05Å; S548-F551 WeakPolarHBondContact OG-CB 3.19Å; S548-F551 PolarHBondContact OG-N 3.29Å; S548-K552 PolarHBondContact O-N 3.35Å
549	E	43.7	Very low	55.3	Low	162 Å²	162	96.5 Å²	96.5	76%	0.757	46%	0.46	S	S	*	.	H	α-helix	trans	-44.6	-33.6	173	-87.1	-86.4	128	0	0	112	V547 K552 G553	V547-E549 PolarHBondContact O-N 2.77Å; E549-K552 WeakPolarHBondContact O-CB 3.35Å; E549-K552 PolarHBondContact O-N 3.17Å; E549-G553 PolarHBondContact O-N 3.39Å; E549-G553 VanDerWaalsContact O-N 3.07Å
550	R	44.7	Very low	52.6	Low	165 Å²	165	101.5 Å²	101.5	62%	0.623	48%	0.482	S	S	*	.	H	α-helix	trans	-83.7	-23	178.6	-133.4	175.9	-168.8	178.6	1.5	115	S548 K552 G553 W554	S548-R550 PolarHBondContact O-N 3.5Å; R550-K552 VanDerWaalsContact C-N 3.3Å; R550-G553 CarbonylContact O-C 3.49Å; R550-G553 WeakPolarHBondContact O-CA 3.41Å; R550-G553 PolarHBondContact O-N 3.15Å; R550-G553 VanDerWaalsContact O-N 3.13Å; R550-W554 PolarHBondContact O-N 3.19Å
551	F	49.3	Very low	50.5	Low	24 Å²	24	97.3 Å²	97.3	11%	0.105	47%	0.468	C	S	.	.	H	α-helix	trans	-65.8	-38.2	165.7	-175.3	-87.7	0	0	0	110	V466 K469 V547 S548 G553 W554 V555	V466-F551 WeakPolarHBondContact O-CE2 3.29Å; K469-F551 HydrophobicContact CB-CE1 3.63Å; K469-F551 HydrophobicContact CB-CZ 4.08Å; K469-F551 HydrophobicContact CD-CE1 4.31Å; K469-F551 HydrophobicContact CG-CD1 4.39Å; K469-F551 HydrophobicContact CG-CE1 3.68Å; V547-F551 HydrophobicContact CG1-CB 4.09Å; V547-F551 HydrophobicContact CG1-CD1 3.55Å; V547-F551 HydrophobicContact CG1-CE1 4.41Å; V547-F551 HydrophobicContact CG1-CG 4.16Å; S548-F551 WeakPolarHBondContact O-CB 3.34Å; S548-F551 PolarHBondContact O-N 2.05Å; S548-F551 WeakPolarHBondContact OG-CB 3.19Å; S548-F551 PolarHBondContact OG-N 3.29Å; F551-G553 VanDerWaalsContact C-N 3.26Å; F551-G553 PolarHBondContact O-N 3.23Å; F551-W554 PolarHBondContact O-N 3.14Å; F551-V555 HydrophobicContact CD1-CG2 3.94Å; F551-V555 HydrophobicContact CE1-CG2 3.6Å; F551-V555 HydrophobicContact CZ-CG2 4.06Å; F551-V555 WeakPolarHBondContact O-CB 3.19Å; F551-V555 VanDerWaalsContact O-CG2 3.25Å; F551-V555 WeakPolarHBondContact O-CG2 3.48Å; F551-V555 PolarHBondContact O-N 3.45Å
552	K	47.2	Very low	48.3	Very low	69 Å²	69	96 Å²	96	30%	0.3	47%	0.471	S	S	.	.	H	α-helix	trans	-61.5	-37.6	168.3	-56.1	177.3	-172.7	170.9	0	110.9	D544 V547 S548 E549 R550 R556	D544-K552 PolarHBondContact O-NZ 3.16Å; V547-K552 HydrophobicContact CG1-CG 3.98Å; S548-K552 PolarHBondContact O-N 3.35Å; E549-K552 WeakPolarHBondContact O-CB 3.35Å; E549-K552 PolarHBondContact O-N 3.17Å; R550-K552 VanDerWaalsContact C-N 3.3Å; K552-R556 VanDerWaalsContact O-CB 3.29Å; K552-R556 WeakPolarHBondContact O-CB 3.28Å; K552-R556 PolarHBondContact O-N 3.31Å
553	G	44.1	Very low	46.3	Very low	25 Å²	25	102.4 Å²	102.4	26%	0.258	50%	0.5	S	S	.	.	H	α-helix	trans	-64.4	-43.9	172.3	0	0	0	0	0	115	E549 R550 F551 R556 L557	E549-G553 PolarHBondContact O-N 3.39Å; E549-G553 VanDerWaalsContact O-N 3.07Å; R550-G553 CarbonylContact O-C 3.49Å; R550-G553 WeakPolarHBondContact O-CA 3.41Å; R550-G553 PolarHBondContact O-N 3.15Å; R550-G553 VanDerWaalsContact O-N 3.13Å; F551-G553 VanDerWaalsContact C-N 3.26Å; F551-G553 PolarHBondContact O-N 3.23Å; G553-R556 CarbonylContact O-C 3.6Å; G553-R556 WeakPolarHBondContact O-CB 3.38Å; G553-R556 PolarHBondContact O-N 2.9Å; G553-L557 PolarHBondContact O-N 3.26Å
554	W	46.7	Very low	44.8	Very low	98 Å²	98	102.1 Å²	102.1	37%	0.371	51%	0.507	S	S	.	.	H	α-helix	trans	-69.2	-41.1	177.4	-168.7	81	0	0	0	111.5	L103 F467 R550 F551 R556 L557 Q558	L103-W554 HydrophobicContact CD1-CZ2 4.18Å; F467-W554 AromaticContact CD1-CH2 3.97Å; F467-W554 HydrophobicContact CD1-CH2 3.97Å; F467-W554 AromaticContact CE1-CH2 3.97Å; F467-W554 HydrophobicContact CE1-CH2 3.97Å; R550-W554 PolarHBondContact O-N 3.19Å; F551-W554 PolarHBondContact O-N 3.14Å; W554-R556 VanDerWaalsContact C-N 3.32Å; W554-R556 PolarHBondContact O-N 3.16Å; W554-L557 WeakPolarHBondContact O-CB 3.39Å; W554-L557 PolarHBondContact O-N 3.17Å; W554-Q558 WeakPolarHBondContact O-CB 3.21Å; W554-Q558 PolarHBondContact O-N 3.04Å
555	V	47.5	Very low	43.3	Very low	46 Å²	46	106.5 Å²	106.5	28%	0.279	52%	0.522	S	S	.	.	H	α-helix	trans	-65.5	-33.6	170.4	172.8	0	0	0	0	111.6	F551 Q558 K559	F551-V555 HydrophobicContact CD1-CG2 3.94Å; F551-V555 HydrophobicContact CE1-CG2 3.6Å; F551-V555 HydrophobicContact CZ-CG2 4.06Å; F551-V555 WeakPolarHBondContact O-CB 3.19Å; F551-V555 VanDerWaalsContact O-CG2 3.25Å; F551-V555 WeakPolarHBondContact O-CG2 3.48Å; F551-V555 PolarHBondContact O-N 3.45Å; V555-Q558 PolarHBondContact O-N 3.23Å; V555-K559 WeakPolarHBondContact O-CB 3.27Å; V555-K559 PolarHBondContact O-N 3.45Å
556	R	37	Very low	41.9	Very low	186 Å²	186	105.5 Å²	105.5	70%	0.702	52%	0.524	S	S	*	.	H	α-helix	trans	-66.4	-43.4	170.5	-102.8	179.5	-178.6	164.7	1.3	112	K552 G553 W554 Q558 K559 M560	K552-R556 VanDerWaalsContact O-CB 3.29Å; K552-R556 WeakPolarHBondContact O-CB 3.28Å; K552-R556 PolarHBondContact O-N 3.31Å; G553-R556 CarbonylContact O-C 3.6Å; G553-R556 WeakPolarHBondContact O-CB 3.38Å; G553-R556 PolarHBondContact O-N 2.9Å; W554-R556 VanDerWaalsContact C-N 3.32Å; W554-R556 PolarHBondContact O-N 3.16Å; R556-Q558 VanDerWaalsContact C-N 3.29Å; R556-Q558 PolarHBondContact O-N 2.03Å; R556-K559 CarbonylContact O-C 3.32Å; R556-K559 PolarHBondContact O-N 2.77Å; R556-M560 WeakPolarHBondContact O-CB 3.46Å; R556-M560 WeakPolarHBondContact O-CG 3.44Å; R556-M560 PolarHBondContact O-N 2.64Å
557	L	39.6	Very low	41	Very low	95 Å²	95	111.9 Å²	111.9	50%	0.497	55%	0.551	S	S	.	*	H	α-helix	trans	-59.9	-39.8	172.3	-96.7	147.7	0	0	0	111.3	G553 W554 M560 T561	G553-L557 PolarHBondContact O-N 3.26Å; W554-L557 WeakPolarHBondContact O-CB 3.39Å; W554-L557 PolarHBondContact O-N 3.17Å; L557-M560 HydrophobicContact CG-CE 4.47Å; L557-M560 PolarHBondContact O-N 3.41Å; L557-T561 WeakPolarHBondContact O-CB 3.36Å; L557-T561 WeakPolarHBondContact O-CG2 3.16Å; L557-T561 PolarHBondContact O-N 3.29Å; L557-T561 PolarHBondContact O-OG1 3.37Å
558	Q	40.8	Very low	39.8	Very low	92 Å²	92	117.7 Å²	117.7	43%	0.43	59%	0.59	S	S	.	*	H	α-helix	trans	-67.5	-36.6	174.8	-159.8	179.7	-10.2	0	0	112.4	W554 V555 R556 T561	W554-Q558 WeakPolarHBondContact O-CB 3.21Å; W554-Q558 PolarHBondContact O-N 3.04Å; V555-Q558 PolarHBondContact O-N 3.23Å; R556-Q558 VanDerWaalsContact C-N 3.29Å; R556-Q558 PolarHBondContact O-N 2.03Å; Q558-T561 WeakPolarHBondContact CA-OG1 3.46Å; Q558-T561 PolarHBondContact O-OG1 3.27Å
559	K	36.9	Very low	38.9	Very low	176 Å²	176	123.4 Å²	123.4	77%	0.765	61%	0.607	S	S	*	*	H	α-helix	trans	-70.8	-33.9	171.5	-93.9	-174.6	172.7	-174.9	0	113.5	V555 R556	V555-K559 WeakPolarHBondContact O-CB 3.27Å; V555-K559 PolarHBondContact O-N 3.45Å; R556-K559 CarbonylContact O-C 3.32Å; R556-K559 PolarHBondContact O-N 2.77Å
560	M	34.1	Very low	38.2	Very low	149 Å²	149	124.2 Å²	124.2	73%	0.734	61%	0.608	S	S	*	*	H	α-helix	trans	-78.4	-22.3	177.4	-73.3	-167.1	-60.4	0	0	113	R556 L557	R556-M560 WeakPolarHBondContact O-CB 3.46Å; R556-M560 WeakPolarHBondContact O-CG 3.44Å; R556-M560 PolarHBondContact O-N 2.64Å; L557-M560 HydrophobicContact CG-CE 4.47Å; L557-M560 PolarHBondContact O-N 3.41Å
561	T	39.4	Very low	37.8	Very low	81 Å²	81	124.1 Å²	124.1	50%	0.497	62%	0.615	S	S	.	*	T	Hydrogen-bonded Turn	trans	-91.4	6.2	-179.7	44.6	0	0	0	0	114.8	L557 Q558 E563	L557-T561 WeakPolarHBondContact O-CB 3.36Å; L557-T561 WeakPolarHBondContact O-CG2 3.16Å; L557-T561 PolarHBondContact O-N 3.29Å; L557-T561 PolarHBondContact O-OG1 3.37Å; Q558-T561 WeakPolarHBondContact CA-OG1 3.46Å; Q558-T561 PolarHBondContact O-OG1 3.27Å; T561-E563 PolarHBondContact O-N 2.97Å
562	G	34.5	Very low	37.1	Very low	65 Å²	65	130.6 Å²	130.6	67%	0.67	65%	0.65	S	S	*	*			trans	62.1	-12.3	150.2	0	0	0	0	0	120.4
563	E	36.1	Very low	36.4	Very low	164 Å²	164	134.5 Å²	134.5	77%	0.766	67%	0.669	S	S	*	*			trans	-140.7	93.2	-174.8	-69.4	-162.6	158.6	0	0	112.5	T561	T561-E563 PolarHBondContact O-N 2.97Å
564	V	37.4	Very low	36.1	Very low	128 Å²	128	141.4 Å²	141.4	78%	0.776	69%	0.687	S	S	*	*			trans	-87.5	87.2	152.2	178.7	0	0	0	0	106.1
565	K	31.6	Very low	35.8	Very low	184 Å²	184	142.2 Å²	142.2	80%	0.8	70%	0.698	S	S	*	*			trans	-157.9	120.7	159.3	-103.7	163.1	-168.3	-174.6	0	108.6
566	I	29	Very low	35.4	Very low	166 Å²	166	145.1 Å²	145.1	85%	0.851	72%	0.716	S	S	*	*			trans	84.5	86.9	167.5	-50.9	161.8	0	0	0	114.8
567	F	35.8	Very low	35.3	Very low	203 Å²	203	143.2 Å²	143.2	89%	0.89	71%	0.713	S	S	*	*			trans	-97.1	85.7	-179.5	-155.8	-90.2	0	0	0	108.3
568	C	31.8	Very low	35.4	Very low	126 Å²	126	142.1 Å²	142.1	85%	0.851	71%	0.713	S	S	*	*	S	Bend	trans	-175.8	-27.1	155.6	-113.6	0	0	0	0	117.4
569	F	29.6	Very low	35.3	Very low	187 Å²	187	143.3 Å²	143.3	82%	0.82	72%	0.722	S	S	*	*	S	Bend	trans	-117.2	-9.3	-159.1	-145.5	-101.5	0	0	0	117.7
570	F	28.8	Very low	35.3	Very low	180 Å²	180	143.7 Å²	143.7	79%	0.789	72%	0.718	S	S	*	*			trans	-119.2	73.2	-172.5	-100	-94.1	0	0	0	113.2
571	Q	36.4	Very low	35.5	Very low	162 Å²	162	141.8 Å²	141.8	76%	0.757	71%	0.707	S	S	*	*			trans	-106.3	3	176.9	-132.1	-175.8	6.5	0	0	115.3
572	L	34.8	Very low	35.7	Very low	160 Å²	160	139.8 Å²	139.8	84%	0.838	70%	0.697	S	S	*	*	S	Bend	trans	-84.6	-36.8	176.6	-135.7	77.3	0	0	0	113.1
573	H	33	Very low	35.9	Very low	152 Å²	152	143.3 Å²	143.3	70%	0.704	69%	0.693	S	S	*	*	H	α-helix	trans	-76.9	-30.9	-177.1	-162.9	-100.4	0	0	0	113.3	L575	H573-L575 VanDerWaalsContact C-N 3.29Å; H573-L575 PolarHBondContact O-N 2.85Å
574	R	37.8	Very low	36.1	Very low	169 Å²	169	140.5 Å²	140.5	64%	0.638	68%	0.681	S	S	*	*	H	α-helix	trans	-73.5	-16.5	176.6	-82.6	-169.4	177.5	-153.5	1.5	114	V576 F577 S578	R574-V576 VanDerWaalsContact C-N 3.29Å; R574-V576 PolarHBondContact O-N 2.97Å; R574-F577 PolarHBondContact O-N 3.41Å; R574-S578 PolarHBondContact O-N 2.85Å; R574-S578 VanDerWaalsContact O-N 3.15Å
575	L	39.7	Very low	36.5	Very low	116 Å²	116	139.8 Å²	139.8	61%	0.607	67%	0.669	S	S	*	*	H	α-helix	trans	-65.5	-35.3	177.4	-139.7	109.5	0	0	0	111.4	H573 L579	H573-L575 VanDerWaalsContact C-N 3.29Å; H573-L575 PolarHBondContact O-N 2.85Å; L575-L579 WeakPolarHBondContact O-CG 3.19Å; L575-L579 PolarHBondContact O-N 3.38Å
576	V	40.2	Very low	37.1	Very low	106 Å²	106	137.8 Å²	137.8	64%	0.642	66%	0.656	S	S	*	*	H	α-helix	trans	-73.8	-37.3	179.3	179.9	0	0	0	0	111.7	R574 L579	R574-V576 VanDerWaalsContact C-N 3.29Å; R574-V576 PolarHBondContact O-N 2.97Å; V576-L579 PolarHBondContact O-N 3.38Å
577	F	33.8	Very low	37.9	Very low	146 Å²	146	135.6 Å²	135.6	64%	0.64	64%	0.642	S	S	*	*	H	α-helix	trans	-75.2	-34.1	-179.3	-140.7	-91	0	0	0	112.6	R574 L579 R580 H581	R574-F577 PolarHBondContact O-N 3.41Å; F577-L579 VanDerWaalsContact C-N 3.27Å; F577-L579 PolarHBondContact O-N 3.49Å; F577-R580 PolarHBondContact O-N 2.93Å; F577-H581 PolarHBondContact O-N 2.7Å
578	S	41.3	Very low	38.5	Very low	72 Å²	72	131 Å²	131	50%	0.503	63%	0.627	S	S	.	*	H	α-helix	trans	-67	-25.7	174.1	-173.9	0	0	0	0	113.3	R574 S582	R574-S578 PolarHBondContact O-N 2.85Å; R574-S578 VanDerWaalsContact O-N 3.15Å; S578-S582 WeakPolarHBondContact O-CB 3.43Å; S578-S582 PolarHBondContact O-N 3.05Å
579	L	39.8	Very low	39.2	Very low	117 Å²	117	130 Å²	130	61%	0.613	61%	0.613	S	S	*	*	H	α-helix	trans	-71.7	-32.1	175.8	-75.5	167	0	0	0	112.1	L575 V576 F577 K583	L575-L579 WeakPolarHBondContact O-CG 3.19Å; L575-L579 PolarHBondContact O-N 3.38Å; V576-L579 PolarHBondContact O-N 3.38Å; F577-L579 VanDerWaalsContact C-N 3.27Å; F577-L579 PolarHBondContact O-N 3.49Å; L579-K583 PolarHBondContact O-N 3.22Å
580	R	35.6	Very low	41	Very low	184 Å²	184	125.9 Å²	125.9	69%	0.694	60%	0.599	S	S	*	*	H	α-helix	trans	-71.2	-45.9	-179.5	-149.1	176.8	-156.3	-171.2	4.4	111.7	F577 S582 K583 E584	F577-R580 PolarHBondContact O-N 2.93Å; R580-S582 PolarHBondContact O-N 3.36Å; R580-K583 WeakPolarHBondContact O-CB 3.39Å; R580-K583 PolarHBondContact O-N 3.43Å; R580-K583 VanDerWaalsContact O-N 3.14Å; R580-E584 PolarHBondContact O-N 3.43Å
581	H	38.9	Very low	43	Very low	109 Å²	109	124.3 Å²	124.3	51%	0.505	59%	0.588	S	S	.	*	H	α-helix	trans	-71.6	-31.4	-179.5	-137.9	-21.8	0	0	0	112.9	F577 K583 E584 E585	F577-H581 PolarHBondContact O-N 2.7Å; H581-K583 PolarHBondContact O-N 2.96Å; H581-E584 IonicContact CE1-OE2 3.99Å; H581-E584 IonicContact ND1-OE2 3.59Å; H581-E584 PolarHBondContact O-N 3.26Å; H581-E585 PolarHBondContact O-N 3.5Å; H581-E585 VanDerWaalsContact O-N 3.09Å
582	S	42.8	Very low	44.3	Very low	39 Å²	39	120.9 Å²	120.9	27%	0.273	57%	0.572	S	S	.	*	H	α-helix	trans	-68.4	-15	172.5	178.2	0	0	0	0	113.5	S578 R580 R586	S578-S582 WeakPolarHBondContact O-CB 3.43Å; S578-S582 PolarHBondContact O-N 3.05Å; R580-S582 PolarHBondContact O-N 3.36Å; S582-R586 PolarHBondContact O-NE 2.97Å; S582-R586 PolarHBondContact OG-NH2 3.28Å
583	K	40.2	Very low	46	Very low	139 Å²	139	119.6 Å²	119.6	60%	0.604	56%	0.562	S	S	*	*	H	α-helix	trans	-82.2	-45.2	175.1	-155.9	-178.3	177.9	-169.1	0	110.4	L579 R580 H581 R586 E587	L579-K583 PolarHBondContact O-N 3.22Å; R580-K583 WeakPolarHBondContact O-CB 3.39Å; R580-K583 PolarHBondContact O-N 3.43Å; R580-K583 VanDerWaalsContact O-N 3.14Å; H581-K583 PolarHBondContact O-N 2.96Å; K583-R586 WeakPolarHBondContact O-CB 3.28Å; K583-R586 PolarHBondContact O-N 2.9Å; K583-E587 PolarHBondContact O-N 3.48Å
584	E	39.3	Very low	48	Very low	106 Å²	106	117.5 Å²	117.5	50%	0.495	55%	0.553	S	S	.	*	H	α-helix	trans	-63	-45.5	174.9	-75.1	168	165.2	0	0	112.2	R580 H581 R586 E587 D588	R580-E584 PolarHBondContact O-N 3.43Å; H581-E584 IonicContact CE1-OE2 3.99Å; H581-E584 IonicContact ND1-OE2 3.59Å; H581-E584 PolarHBondContact O-N 3.26Å; E584-R586 PolarHBondContact O-N 2.97Å; E584-R586 VanDerWaalsContact O-N 3.1Å; E584-E587 PolarHBondContact O-N 2.97Å; E584-E587 VanDerWaalsContact O-N 3.14Å; E584-D588 PolarHBondContact O-N 3.5Å; E584-D588 VanDerWaalsContact O-N 3.12Å
585	E	47	Very low	50	Low	113 Å²	113	112.3 Å²	112.3	53%	0.528	54%	0.535	S	S	.	.	H	α-helix	trans	-61.5	-23.1	175.5	-86.2	-172.3	145.2	0	0	113.5	H581 L589	H581-E585 PolarHBondContact O-N 3.5Å; H581-E585 VanDerWaalsContact O-N 3.09Å; E585-L589 WeakPolarHBondContact O-CD1 3.39Å; E585-L589 WeakPolarHBondContact O-CG 3.45Å; E585-L589 PolarHBondContact O-N 3.45Å
586	R	43.4	Very low	51.9	Low	141 Å²	141	114.9 Å²	114.9	53%	0.532	54%	0.537	S	S	.	.	H	α-helix	trans	-78.2	-41.1	178.1	-139.6	177.3	-60.6	-150.7	1.3	111	S582 K583 E584 D590	S582-R586 PolarHBondContact O-NE 2.97Å; S582-R586 PolarHBondContact OG-NH2 3.28Å; K583-R586 WeakPolarHBondContact O-CB 3.28Å; K583-R586 PolarHBondContact O-N 2.9Å; E584-R586 PolarHBondContact O-N 2.97Å; E584-R586 VanDerWaalsContact O-N 3.1Å; R586-D590 PolarHBondContact O-N 2.98Å; R586-D590 VanDerWaalsContact O-N 3.14Å
587	E	45.9	Very low	53.7	Low	120 Å²	120	111.9 Å²	111.9	56%	0.561	52%	0.523	S	S	*	.	H	α-helix	trans	-66.2	-37.9	177.5	-70.9	177.7	177.6	0	0	111.4	K583 E584 W591	K583-E587 PolarHBondContact O-N 3.48Å; E584-E587 PolarHBondContact O-N 2.97Å; E584-E587 VanDerWaalsContact O-N 3.14Å; E587-W591 WeakPolarHBondContact O-CB 3.47Å; E587-W591 PolarHBondContact O-N 3.43Å
588	D	47.6	Very low	55.9	Low	108 Å²	108	111.8 Å²	111.8	58%	0.578	52%	0.519	S	S	*	.	H	α-helix	trans	-68.1	-39.2	177.8	-69.7	-24.9	0	0	0	113.1	E584 W591 E592	E584-D588 PolarHBondContact O-N 3.5Å; E584-D588 VanDerWaalsContact O-N 3.12Å; D588-W591 PolarHBondContact O-N 3.41Å; D588-E592 PolarHBondContact O-N 3.08Å
589	L	48.1	Very low	58	Low	104 Å²	104	115.3 Å²	115.3	55%	0.545	52%	0.521	S	S	.	.	H	α-helix	trans	-70.8	-39.4	178.5	-82.4	166.2	0	0	0	112.5	E585 W591 Q593	E585-L589 WeakPolarHBondContact O-CD1 3.39Å; E585-L589 WeakPolarHBondContact O-CG 3.45Å; E585-L589 PolarHBondContact O-N 3.45Å; L589-W591 VanDerWaalsContact C-N 3.33Å; L589-Q593 WeakPolarHBondContact O-CG 3.25Å; L589-Q593 PolarHBondContact O-N 3.03Å; L589-Q593 VanDerWaalsContact O-N 3.14Å
590	D	66.7	Low	60	Low	101 Å²	101	112.3 Å²	112.3	54%	0.54	51%	0.513	S	S	.	.	H	α-helix	trans	-66.2	-39.1	175.8	-73.3	-16.5	0	0	0	110.3	R586 Q593 E594	R586-D590 PolarHBondContact O-N 2.98Å; R586-D590 VanDerWaalsContact O-N 3.14Å; D590-Q593 PolarHBondContact O-N 2.92Å; D590-E594 WeakPolarHBondContact O-CB 3.47Å; D590-E594 PolarHBondContact O-N 3.35Å
591	W	69.7	Low	62.4	Low	146 Å²	146	112.3 Å²	112.3	55%	0.553	51%	0.513	S	S	*	.	H	α-helix	trans	-62.5	-47.4	174.6	-178.3	90.4	0	0	0	112.6	E587 D588 L589 Q593 E594 E595	E587-W591 WeakPolarHBondContact O-CB 3.47Å; E587-W591 PolarHBondContact O-N 3.43Å; D588-W591 PolarHBondContact O-N 3.41Å; L589-W591 VanDerWaalsContact C-N 3.33Å; W591-Q593 VanDerWaalsContact C-N 3.34Å; W591-Q593 PolarHBondContact O-N 3.38Å; W591-E594 PolarHBondContact O-N 2.9Å; W591-E595 HydrophobicContact CH2-CG 4.47Å; W591-E595 WeakPolarHBondContact CH2-OE2 3.5Å; W591-E595 HydrophobicContact CZ2-CG 4.43Å; W591-E595 VanDerWaalsContact CZ3-OE2 3.3Å; W591-E595 WeakPolarHBondContact CZ3-OE2 3.12Å; W591-E595 WeakPolarHBondContact O-CB 3.47Å; W591-E595 PolarHBondContact O-N 3.44Å
592	E	64.7	Low	64.6	Low	90 Å²	90	114.2 Å²	114.2	42%	0.421	52%	0.52	S	S	.	.	H	α-helix	trans	-61.7	-39.6	178.1	-94.2	-159.5	-165.6	0	0	112.6	D588 E595 R596	D588-E592 PolarHBondContact O-N 3.08Å; E592-E595 PolarHBondContact O-N 2.73Å; E592-R596 WeakPolarHBondContact O-CG 3.24Å; E592-R596 PolarHBondContact O-N 2.73Å; E592-R596 IonicContact OE2-CZ 2.68Å; E592-R596 IonicContact OE2-NH2 3.56Å; E592-R596 PolarHBondContact OE2-NH2 2.92Å
593	Q	70.6	Confident	66.7	Low	133 Å²	133	117.6 Å²	117.6	62%	0.621	53%	0.532	S	S	*	.	H	α-helix	trans	-66.7	-41.4	177.6	-75	-174.6	7.5	0	0	111.6	L589 D590 W591 E595 R596 A597	L589-Q593 WeakPolarHBondContact O-CG 3.25Å; L589-Q593 PolarHBondContact O-N 3.03Å; L589-Q593 VanDerWaalsContact O-N 3.14Å; D590-Q593 PolarHBondContact O-N 2.92Å; W591-Q593 VanDerWaalsContact C-N 3.34Å; W591-Q593 PolarHBondContact O-N 3.38Å; Q593-E595 VanDerWaalsContact C-N 3.35Å; Q593-R596 PolarHBondContact O-N 3.13Å; Q593-A597 WeakPolarHBondContact O-CB 3.45Å; Q593-A597 PolarHBondContact O-N 3.12Å
594	E	75.8	Confident	68.8	Low	109 Å²	109	113.5 Å²	113.5	51%	0.509	52%	0.524	S	S	.	.	H	α-helix	trans	-67.1	-38.1	177.7	-157	-176.5	-156.3	0	0	111.5	D590 W591 A597 R598	D590-E594 WeakPolarHBondContact O-CB 3.47Å; D590-E594 PolarHBondContact O-N 3.35Å; W591-E594 PolarHBondContact O-N 2.9Å; E594-A597 PolarHBondContact O-N 3.37Å; E594-R598 WeakPolarHBondContact O-CG 3.44Å; E594-R598 PolarHBondContact O-N 2.89Å; E594-R598 IonicContact OE1-NH2 3.83Å; E594-R598 IonicContact OE2-CZ 3.4Å; E594-R598 IonicContact OE2-NH2 3.11Å; E594-R598 PolarHBondContact OE2-NH2 3.31Å
595	E	77.9	Confident	71	Confident	60 Å²	60	115.7 Å²	115.7	28%	0.28	53%	0.531	S	S	.	.	H	α-helix	trans	-66.4	-41.5	176.9	-142.8	-157.1	157.4	0	0	112	W591 E592 Q593 A597 R598 R599	W591-E595 HydrophobicContact CH2-CG 4.47Å; W591-E595 WeakPolarHBondContact CH2-OE2 3.5Å; W591-E595 HydrophobicContact CZ2-CG 4.43Å; W591-E595 VanDerWaalsContact CZ3-OE2 3.3Å; W591-E595 WeakPolarHBondContact CZ3-OE2 3.12Å; W591-E595 WeakPolarHBondContact O-CB 3.47Å; W591-E595 PolarHBondContact O-N 3.44Å; E592-E595 PolarHBondContact O-N 2.73Å; Q593-E595 VanDerWaalsContact C-N 3.35Å; E595-A597 PolarHBondContact O-N 2.93Å; E595-R598 PolarHBondContact O-N 2.92Å; E595-R599 WeakPolarHBondContact O-CG 3.34Å; E595-R599 PolarHBondContact O-N 3.2Å; E595-R599 IonicContact OE1-CZ 3.66Å; E595-R599 IonicContact OE1-NE 3.67Å; E595-R599 IonicContact OE1-NH2 2.81Å; E595-R599 PolarHBondContact OE1-NH2 3.42Å; E595-R599 IonicContact OE2-NH2 3.5Å; E595-R599 PolarHBondContact OE2-NH2 2.94Å
596	R	79.9	Confident	72.8	Confident	169 Å²	169	116.3 Å²	116.3	64%	0.638	53%	0.534	S	S	*	.	H	α-helix	trans	-62.7	-41.1	173.1	-72.6	-178.6	-156.5	-170.5	9.2	111.9	E592 Q593 R598 R599 A600	E592-R596 WeakPolarHBondContact O-CG 3.24Å; E592-R596 PolarHBondContact O-N 2.73Å; E592-R596 IonicContact OE2-CZ 2.68Å; E592-R596 IonicContact OE2-NH2 3.56Å; E592-R596 PolarHBondContact OE2-NH2 2.92Å; Q593-R596 PolarHBondContact O-N 3.13Å; R596-R598 VanDerWaalsContact C-N 3.33Å; R596-R598 PolarHBondContact O-N 3.38Å; R596-R599 PolarHBondContact O-N 3.1Å; R596-A600 WeakPolarHBondContact O-CB 3.14Å; R596-A600 PolarHBondContact O-N 3.38Å
597	A	78	Confident	74.6	Confident	43 Å²	43	118.4 Å²	118.4	36%	0.355	54%	0.542	S	S	.	.	H	α-helix	trans	-63.8	-37.8	175.7	0	0	0	0	0	112	Q593 E594 E595 R601	Q593-A597 WeakPolarHBondContact O-CB 3.45Å; Q593-A597 PolarHBondContact O-N 3.12Å; E594-A597 PolarHBondContact O-N 3.37Å; E595-A597 PolarHBondContact O-N 2.93Å; A597-R601 VanDerWaalsContact O-CG 3.31Å; A597-R601 WeakPolarHBondContact O-CG 3.43Å; A597-R601 PolarHBondContact O-N 3.19Å; A597-R601 VanDerWaalsContact O-N 3.08Å
598	R	80.4	Confident	76.2	Confident	144 Å²	144	119.3 Å²	119.3	54%	0.543	55%	0.548	S	S	.	.	H	α-helix	trans	-65.5	-42.5	174	-72.1	179.5	-147.5	-165.9	8.1	112.2	E594 E595 R596 R601 K602	E594-R598 WeakPolarHBondContact O-CG 3.44Å; E594-R598 PolarHBondContact O-N 2.89Å; E594-R598 IonicContact OE1-NH2 3.83Å; E594-R598 IonicContact OE2-CZ 3.4Å; E594-R598 IonicContact OE2-NH2 3.11Å; E594-R598 PolarHBondContact OE2-NH2 3.31Å; E595-R598 PolarHBondContact O-N 2.92Å; R596-R598 VanDerWaalsContact C-N 3.33Å; R596-R598 PolarHBondContact O-N 3.38Å; R598-R601 PolarHBondContact O-N 2.92Å; R598-K602 PolarHBondContact O-N 3.13Å
599	R	84.7	Confident	77.6	Confident	146 Å²	146	123.2 Å²	123.2	55%	0.551	56%	0.555	S	S	*	*	H	α-helix	trans	-63.3	-46.4	176.7	-70	-178.8	-165.5	-173.4	7.2	111.7	E595 R596 R601 K602 E603	E595-R599 WeakPolarHBondContact O-CG 3.34Å; E595-R599 PolarHBondContact O-N 3.2Å; E595-R599 IonicContact OE1-CZ 3.66Å; E595-R599 IonicContact OE1-NE 3.67Å; E595-R599 IonicContact OE1-NH2 2.81Å; E595-R599 PolarHBondContact OE1-NH2 3.42Å; E595-R599 IonicContact OE2-NH2 3.5Å; E595-R599 PolarHBondContact OE2-NH2 2.94Å; R596-R599 PolarHBondContact O-N 3.1Å; R599-R601 VanDerWaalsContact C-N 3.3Å; R599-R601 PolarHBondContact O-N 2.73Å; R599-K602 WeakPolarHBondContact O-CB 3.48Å; R599-K602 PolarHBondContact O-N 3.14Å; R599-K602 VanDerWaalsContact O-N 3.09Å; R599-E603 PolarHBondContact O-N 2.98Å
600	A	82.1	Confident	78.8	Confident	55 Å²	55	121 Å²	121	46%	0.455	55%	0.551	S	S	.	*	H	α-helix	trans	-60.1	-38	176.1	0	0	0	0	0	112.8	R596 A604	R596-A600 WeakPolarHBondContact O-CB 3.14Å; R596-A600 PolarHBondContact O-N 3.38Å; A600-A604 WeakPolarHBondContact O-CB 3.41Å; A600-A604 PolarHBondContact O-N 3.25Å
601	R	87.7	Confident	79.1	Confident	183 Å²	183	123.4 Å²	123.4	69%	0.691	56%	0.557	S	S	*	*	H	α-helix	trans	-67.3	-35.7	174.9	-75.2	174.4	-178.6	179.3	2.4	112.9	A597 R598 R599 K605	A597-R601 VanDerWaalsContact O-CG 3.31Å; A597-R601 WeakPolarHBondContact O-CG 3.43Å; A597-R601 PolarHBondContact O-N 3.19Å; A597-R601 VanDerWaalsContact O-N 3.08Å; R598-R601 PolarHBondContact O-N 2.92Å; R599-R601 VanDerWaalsContact C-N 3.3Å; R599-R601 PolarHBondContact O-N 2.73Å; R601-K605 WeakPolarHBondContact O-CG 3.37Å; R601-K605 PolarHBondContact O-N 2.96Å; R601-K605 VanDerWaalsContact O-N 3.12Å
602	K	84.8	Confident	79.1	Confident	150 Å²	150	119 Å²	119	65%	0.652	55%	0.551	S	S	*	*	H	α-helix	trans	-66.2	-49.2	174.1	-86.7	-173.2	173.5	-176.1	0	111.1	R598 R599 A604 K605 E606	R598-K602 PolarHBondContact O-N 3.13Å; R599-K602 WeakPolarHBondContact O-CB 3.48Å; R599-K602 PolarHBondContact O-N 3.14Å; R599-K602 VanDerWaalsContact O-N 3.09Å; K602-A604 VanDerWaalsContact C-N 3.3Å; K602-A604 PolarHBondContact O-N 3.33Å; K602-K605 PolarHBondContact O-N 3.2Å; K602-K605 VanDerWaalsContact O-N 3.11Å; K602-E606 PolarHBondContact O-N 3.47Å
603	E	86	Confident	79.1	Confident	110 Å²	110	120.6 Å²	120.6	51%	0.514	56%	0.563	S	S	.	*	H	α-helix	trans	-60.5	-39.2	178	-70.8	176.8	-172.6	0	0	112.1	R599 E606 R607	R599-E603 PolarHBondContact O-N 2.98Å; E603-E606 PolarHBondContact O-N 3.46Å; E603-R607 WeakPolarHBondContact O-CB 3.29Å; E603-R607 WeakPolarHBondContact O-CG 3.27Å; E603-R607 PolarHBondContact O-N 2.91Å
604	A	84.4	Confident	78.8	Confident	53 Å²	53	119.6 Å²	119.6	44%	0.438	57%	0.566	S	S	.	*	H	α-helix	trans	-64.4	-41.1	175.1	0	0	0	0	0	112.4	A600 K602 R607 M608	A600-A604 WeakPolarHBondContact O-CB 3.41Å; A600-A604 PolarHBondContact O-N 3.25Å; K602-A604 VanDerWaalsContact C-N 3.3Å; K602-A604 PolarHBondContact O-N 3.33Å; A604-R607 PolarHBondContact O-N 3.35Å; A604-M608 WeakPolarHBondContact O-CB 3.16Å; A604-M608 VanDerWaalsContact O-CG 3.26Å; A604-M608 WeakPolarHBondContact O-CG 3.49Å; A604-M608 PolarHBondContact O-N 2.83Å
605	K	85.1	Confident	77.9	Confident	151 Å²	151	121.2 Å²	121.2	66%	0.657	58%	0.578	S	S	*	*	H	α-helix	trans	-66	-38.6	175.2	-80.5	-176.3	177	-175.8	0	112.2	R601 K602 M608 R609	R601-K605 WeakPolarHBondContact O-CG 3.37Å; R601-K605 PolarHBondContact O-N 2.96Å; R601-K605 VanDerWaalsContact O-N 3.12Å; K602-K605 PolarHBondContact O-N 3.2Å; K602-K605 VanDerWaalsContact O-N 3.11Å; K605-M608 PolarHBondContact O-N 3.37Å; K605-R609 WeakPolarHBondContact O-CG 3.43Å; K605-R609 PolarHBondContact O-N 3.35Å
606	E	84.8	Confident	77	Confident	126 Å²	126	123.6 Å²	123.6	59%	0.589	60%	0.597	S	S	*	*	H	α-helix	trans	-66.9	-41.9	176.3	-75	173.9	-177.4	0	0	111.7	K602 E603 M608 R609 A610	K602-E606 PolarHBondContact O-N 3.47Å; E603-E606 PolarHBondContact O-N 3.46Å; E606-M608 VanDerWaalsContact C-N 3.34Å; E606-M608 PolarHBondContact O-N 2.88Å; E606-R609 PolarHBondContact O-N 3.3Å; E606-A610 WeakPolarHBondContact O-CB 3.36Å; E606-A610 PolarHBondContact O-N 2.92Å
607	R	81.5	Confident	75.8	Confident	186 Å²	186	118.8 Å²	118.8	70%	0.702	60%	0.599	S	S	*	*	H	α-helix	trans	-62.9	-37.9	173.4	-74.1	178.9	-178.6	-175.5	2.6	112.9	E603 A604 K611	E603-R607 WeakPolarHBondContact O-CB 3.29Å; E603-R607 WeakPolarHBondContact O-CG 3.27Å; E603-R607 PolarHBondContact O-N 2.91Å; A604-R607 PolarHBondContact O-N 3.35Å; R607-K611 PolarHBondContact O-N 3.27Å
608	M	78.9	Confident	74.6	Confident	139 Å²	139	120.1 Å²	120.1	69%	0.685	62%	0.617	S	S	*	*	H	α-helix	trans	-67	-41.5	175.2	-74.2	-79.6	-78.6	0	0	111.8	A604 K605 E606 K611 A612	A604-M608 WeakPolarHBondContact O-CB 3.16Å; A604-M608 VanDerWaalsContact O-CG 3.26Å; A604-M608 WeakPolarHBondContact O-CG 3.49Å; A604-M608 PolarHBondContact O-N 2.83Å; K605-M608 PolarHBondContact O-N 3.37Å; E606-M608 VanDerWaalsContact C-N 3.34Å; E606-M608 PolarHBondContact O-N 2.88Å; M608-K611 PolarHBondContact O-N 2.79Å; M608-A612 PolarHBondContact O-N 2.72Å
609	R	76.8	Confident	72.8	Confident	190 Å²	190	125.8 Å²	125.8	72%	0.717	65%	0.65	S	S	*	*	H	α-helix	trans	-65.9	-39.8	174.5	-76.3	178	174.2	-176.9	-4	112.4	K605 E606 K611 A612 N613	K605-R609 WeakPolarHBondContact O-CG 3.43Å; K605-R609 PolarHBondContact O-N 3.35Å; E606-R609 PolarHBondContact O-N 3.3Å; R609-K611 VanDerWaalsContact C-N 3.34Å; R609-A612 PolarHBondContact O-N 2.97Å; R609-N613 PolarHBondContact O-N 3.24Å
610	A	74.8	Confident	72.2	Confident	56 Å²	56	124.8 Å²	124.8	46%	0.463	66%	0.655	S	S	.	*	H	α-helix	trans	-63.3	-40	175.7	0	0	0	0	0	111.7	E606 V614	E606-A610 WeakPolarHBondContact O-CB 3.36Å; E606-A610 PolarHBondContact O-N 2.92Å; A610-V614 WeakPolarHBondContact O-CG2 3.46Å; A610-V614 PolarHBondContact O-N 2.9Å
611	K	73.3	Confident	71.7	Confident	152 Å²	152	128.4 Å²	128.4	66%	0.661	67%	0.666	S	S	*	*	H	α-helix	trans	-64.8	-44	172.4	-88.3	-173	171.6	-172	0	112.8	R607 M608 R609 N613 V614 D615	R607-K611 PolarHBondContact O-N 3.27Å; M608-K611 PolarHBondContact O-N 2.79Å; R609-K611 VanDerWaalsContact C-N 3.34Å; K611-N613 VanDerWaalsContact C-N 3.31Å; K611-N613 PolarHBondContact O-N 3.26Å; K611-V614 PolarHBondContact O-N 3.04Å; K611-V614 VanDerWaalsContact O-N 3.16Å; K611-D615 PolarHBondContact O-N 2.72Å
612	A	69.8	Low	70.8	Confident	53 Å²	53	125.4 Å²	125.4	44%	0.438	66%	0.664	S	S	.	*	H	α-helix	trans	-62.4	-36.1	179.5	0	0	0	0	0	113	M608 R609 V614 D615 T616	M608-A612 PolarHBondContact O-N 2.72Å; R609-A612 PolarHBondContact O-N 2.97Å; A612-V614 VanDerWaalsContact C-N 3.34Å; A612-D615 PolarHBondContact O-N 2.81Å; A612-T616 PolarHBondContact O-N 2.97Å; A612-T616 PolarHBondContact O-OG1 3.48Å
613	N	63.8	Low	70	Confident	124 Å²	124	123.9 Å²	123.9	66%	0.663	67%	0.665	S	S	*	*	H	α-helix	trans	-72	-25.3	176.4	-89.2	7.4	0	0	0	113.8	R609 K611 T616	R609-N613 PolarHBondContact O-N 3.24Å; K611-N613 VanDerWaalsContact C-N 3.31Å; K611-N613 PolarHBondContact O-N 3.26Å; N613-T616 PolarHBondContact O-OG1 3.17Å
614	V	64.6	Low	69	Low	113 Å²	113	124.8 Å²	124.8	69%	0.685	67%	0.674	S	S	*	*	H	α-helix	trans	-75.2	-34.2	176.1	172.5	0	0	0	0	110.8	A610 K611 A612	A610-V614 WeakPolarHBondContact O-CG2 3.46Å; A610-V614 PolarHBondContact O-N 2.9Å; K611-V614 PolarHBondContact O-N 3.04Å; K611-V614 VanDerWaalsContact O-N 3.16Å; A612-V614 VanDerWaalsContact C-N 3.34Å
615	D	57.3	Low	68	Low	142 Å²	142	129.6 Å²	129.6	76%	0.759	69%	0.69	S	S	*	*	H	α-helix	trans	-76.2	-19.8	178.3	-72.7	-25	0	0	0	113.5	K611 A612	K611-D615 PolarHBondContact O-N 2.72Å; A612-D615 PolarHBondContact O-N 2.81Å
616	T	59.1	Low	66.8	Low	111 Å²	111	128.1 Å²	128.1	68%	0.681	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.1	-6.4	177.2	48.6	0	0	0	0	114.8	A612 N613	A612-T616 PolarHBondContact O-N 2.97Å; A612-T616 PolarHBondContact O-OG1 3.48Å; N613-T616 PolarHBondContact O-OG1 3.17Å
617	G	53.3	Low	65.4	Low	67 Å²	67	128.2 Å²	128.2	69%	0.691	70%	0.7	S	S	*	*	S	Bend	trans	-94	6.4	-176.9	0	0	0	0	0	115.4
618	G	53.6	Low	64	Low	71 Å²	71	123.4 Å²	123.4	73%	0.732	70%	0.7	S	S	*	*			trans	-116.2	60.6	179.8	0	0	0	0	0	112.5
619	Q	43.2	Very low	62.7	Low	263 Å²	263	122 Å²	122	100%	1.229	70%	0.702	S	S	*	*			trans	-129.5	0	158.8	-94	-172.3	-18.2	0	0	109.3

Retrieved 619 of 619 residues in 4683.9 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).