A0A087X9X1_POEFO Loading...

Gasdermin Eb

AlphaFold DB , UniProt , Accession A0A087X9X1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 461 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M76.3Confident83.1Confident50 Ų5040 Ų4025%0.24620%0.2CC..  0-77.10-64.9-169.5-72.900114A3 I4 A5 L109 V168 E170 V206 M208M1-A3 PolarHBondContact O-N 2.85Å; M1-I4 PolarHBondContact O-N 3Å; M1-I4 VanDerWaalsContact O-N 3.12Å; M1-A5 PolarHBondContact O-N 3.07Å; M1-L109 HydrophobicContact CB-CD1 4.33Å; M1-L109 HydrophobicContact CG-CD1 4.06Å; M1-V168 HydrophobicContact CB-CG1 4.17Å; M1-E170 HydrophobicContact CG-CB 3.88Å; M1-E170 WeakPolarHBondContact CG-OE2 3.41Å; M1-E170 HydrophobicContact SD-CB 3.57Å; M1-E170 VanDerWaalsContact SD-CB 3.57Å; M1-V206 HydrophobicContact CE-CB 4.08Å; M1-V206 HydrophobicContact CE-CG1 3.37Å; M1-V206 HydrophobicContact SD-CB 4.06Å; M1-V206 HydrophobicContact SD-CG1 4.02Å; M1-M208 HydrophobicContact CB-CE 4.42Å; M1-M208 HydrophobicContact CB-SD 4.39Å; M1-M208 HydrophobicContact CE-CB 4.01Å; M1-M208 HydrophobicContact CE-CE 4.02Å; M1-M208 HydrophobicContact SD-CB 4.47Å
2F82.5Confident83.1Confident10 Ų1046.8 Ų46.84%0.04423%0.23CC..Hα-helixtrans-53.5-54.8-171.8-176.4-108.3000114.4I4 A5 T6 V22 L25 M208 I210 T214 I216F2-I4 PolarHBondContact O-N 2.74Å; F2-A5 WeakPolarHBondContact O-CB 3.38Å; F2-A5 PolarHBondContact O-N 3.22Å; F2-T6 HydrophobicContact CD1-CG2 4.26Å; F2-T6 HydrophobicContact CD2-CG2 4.24Å; F2-T6 HydrophobicContact CE1-CG2 3.85Å; F2-T6 HydrophobicContact CE2-CG2 3.81Å; F2-T6 HydrophobicContact CG-CG2 4.45Å; F2-T6 HydrophobicContact CZ-CG2 3.6Å; F2-T6 PolarHBondContact O-N 3.37Å; F2-T6 PolarHBondContact O-OG1 3Å; F2-V22 HydrophobicContact CE1-CB 4.23Å; F2-V22 HydrophobicContact CE1-CG1 4.01Å; F2-L25 HydrophobicContact CD1-CD2 4.16Å; F2-L25 HydrophobicContact CD1-CG 3.96Å; F2-L25 HydrophobicContact CD2-CD2 3.68Å; F2-L25 HydrophobicContact CD2-CG 4.02Å; F2-L25 HydrophobicContact CE1-CD2 3.9Å; F2-L25 HydrophobicContact CE1-CG 4.1Å; F2-L25 HydrophobicContact CE2-CD2 3.4Å; F2-L25 VanDerWaalsContact CE2-CD2 3.4Å; F2-L25 HydrophobicContact CE2-CG 4.18Å; F2-L25 HydrophobicContact CG-CD2 4.06Å; F2-L25 HydrophobicContact CG-CG 3.91Å; F2-L25 HydrophobicContact CZ-CD2 3.52Å; F2-L25 HydrophobicContact CZ-CG 4.22Å; F2-M208 HydrophobicContact CB-SD 3.68Å; F2-I210 HydrophobicContact CD2-CD1 3.75Å; F2-I210 HydrophobicContact CD2-CG1 4.27Å; F2-I210 HydrophobicContact CE2-CD1 3.86Å; F2-I210 HydrophobicContact CE2-CG1 4.4Å; F2-T214 HydrophobicContact CE2-CG2 4.44Å; F2-T214 HydrophobicContact CZ-CG2 4.24Å; F2-I216 HydrophobicContact CE2-CG2 4.4Å; F2-I216 HydrophobicContact CZ-CG2 4.44Å
3A82.6Confident83.1Confident41 Ų4146.5 Ų46.534%0.33923%0.233SC..Hα-helixtrans-56.2-35179.300000113.6M1 T6 K7 S23M1-A3 PolarHBondContact O-N 2.85Å; A3-T6 PolarHBondContact O-OG1 2.84Å; A3-T6 VanDerWaalsContact O-OG1 3.06Å; A3-K7 VanDerWaalsContact O-CB 3.23Å; A3-K7 WeakPolarHBondContact O-CB 3.37Å; A3-K7 PolarHBondContact O-N 3.5Å; A3-S23 WeakPolarHBondContact CB-O 3.34Å
4I78.4Confident83.2Confident75 Ų7545 Ų4539%0.38523%0.226SC..Hα-helixtrans-71.5-44.3178.5-57.2172.9000109.4M1 F2 T6 K7 N8 L109M1-I4 PolarHBondContact O-N 3Å; M1-I4 VanDerWaalsContact O-N 3.12Å; F2-I4 PolarHBondContact O-N 2.74Å; I4-T6 PolarHBondContact O-N 3.39Å; I4-K7 PolarHBondContact O-N 3.04Å; I4-N8 WeakPolarHBondContact O-CB 3.49Å; I4-N8 VanDerWaalsContact O-CG 3.26Å; I4-N8 PolarHBondContact O-N 3Å; I4-L109 HydrophobicContact CB-CD2 3.79Å; I4-L109 HydrophobicContact CG2-CD2 3.48Å; I4-L109 VanDerWaalsContact CG2-CD2 3.48Å
5A83.7Confident81.9Confident0 Ų050.8 Ų50.80%026%0.258CS..Hα-helixtrans-62.2-43.2178.600000112.2M1 F2 N8 F9 S111 F113 V168M1-A5 PolarHBondContact O-N 3.07Å; F2-A5 WeakPolarHBondContact O-CB 3.38Å; F2-A5 PolarHBondContact O-N 3.22Å; A5-N8 PolarHBondContact O-N 3.47Å; A5-F9 WeakPolarHBondContact O-CB 3.31Å; A5-F9 PolarHBondContact O-N 2.61Å; A5-S111 VanDerWaalsContact CB-OG 3.23Å; A5-S111 WeakPolarHBondContact CB-OG 3.49Å; A5-F113 HydrophobicContact CB-CE1 4.43Å; A5-F113 HydrophobicContact CB-CE2 4.25Å; A5-F113 HydrophobicContact CB-CZ 3.58Å; A5-V168 HydrophobicContact CB-CG1 4.01Å; A5-V168 HydrophobicContact CB-CG2 3.7Å
6T88.4Confident80.9Confident0 Ų060.2 Ų60.20%029%0.289CS..Hα-helixtrans-69.3-39.1177.257.30000112.3F2 A3 I4 F9 V10 V22 F113 I216F2-T6 HydrophobicContact CD1-CG2 4.26Å; F2-T6 HydrophobicContact CD2-CG2 4.24Å; F2-T6 HydrophobicContact CE1-CG2 3.85Å; F2-T6 HydrophobicContact CE2-CG2 3.81Å; F2-T6 HydrophobicContact CG-CG2 4.45Å; F2-T6 HydrophobicContact CZ-CG2 3.6Å; F2-T6 PolarHBondContact O-N 3.37Å; F2-T6 PolarHBondContact O-OG1 3Å; A3-T6 PolarHBondContact O-OG1 2.84Å; A3-T6 VanDerWaalsContact O-OG1 3.06Å; I4-T6 PolarHBondContact O-N 3.39Å; T6-F9 PolarHBondContact O-N 3.22Å; T6-V10 WeakPolarHBondContact O-CG2 3.3Å; T6-V10 PolarHBondContact O-N 2.93Å; T6-V22 WeakPolarHBondContact CB-O 3.27Å; T6-V22 PolarHBondContact OG1-O 3.03Å; T6-F113 HydrophobicContact CG2-CZ 4.13Å; T6-I216 WeakPolarHBondContact CB-O 3.46Å; T6-I216 HydrophobicContact CG2-CB 4.02Å; T6-I216 HydrophobicContact CG2-CG2 4.44Å; T6-I216 WeakPolarHBondContact CG2-O 3.39Å
7K84.3Confident80.6Confident89 Ų8960.5 Ų60.539%0.38731%0.312SS..Hα-helixtrans-59.1-47.3172.8-177.5-176.6177.4-173.40111.3A3 I4 V10 K11 D368A3-K7 VanDerWaalsContact O-CB 3.23Å; A3-K7 WeakPolarHBondContact O-CB 3.37Å; A3-K7 PolarHBondContact O-N 3.5Å; I4-K7 PolarHBondContact O-N 3.04Å; K7-V10 PolarHBondContact O-N 3.2Å; K7-K11 WeakPolarHBondContact O-CB 3.33Å; K7-K11 PolarHBondContact O-N 3.31Å; K7-D368 VanDerWaalsContact NZ-CG 3.31Å; K7-D368 IonicContact NZ-OD1 3.06Å; K7-D368 PolarHBondContact NZ-OD1 2.95Å; K7-D368 IonicContact NZ-OD2 3.37Å; K7-D368 PolarHBondContact NZ-OD2 2.96Å
8N80.8Confident80.8Confident13 Ų1362.8 Ų62.87%0.0732%0.324CS..Hα-helixtrans-63.7-44.7178.1-72.4-9.9000111.5I4 A5 V10 K11 E12I4-N8 WeakPolarHBondContact O-CB 3.49Å; I4-N8 VanDerWaalsContact O-CG 3.26Å; I4-N8 PolarHBondContact O-N 3Å; A5-N8 PolarHBondContact O-N 3.47Å; N8-V10 PolarHBondContact O-N 3.31Å; N8-K11 WeakPolarHBondContact O-CB 3.49Å; N8-K11 PolarHBondContact O-N 3.45Å; N8-E12 PolarHBondContact O-N 3.44Å; N8-E12 VanDerWaalsContact O-N 3.12Å
9F87.3Confident81.4Confident0 Ų060.7 Ų60.70%031%0.313CS..Hα-helixtrans-54.4-53.8174.3166.4-98.3000112A5 T6 K11 E12 V13 F75 I76 Y78 F113 L116 I160 I216 A217A5-F9 WeakPolarHBondContact O-CB 3.31Å; A5-F9 PolarHBondContact O-N 2.61Å; T6-F9 PolarHBondContact O-N 3.22Å; F9-K11 VanDerWaalsContact C-N 3.29Å; F9-K11 PolarHBondContact O-N 3.43Å; F9-E12 PolarHBondContact O-N 2.85Å; F9-E12 VanDerWaalsContact O-N 3.14Å; F9-V13 HydrophobicContact CD1-CG2 4.2Å; F9-V13 HydrophobicContact CD2-CG1 3.92Å; F9-V13 HydrophobicContact CD2-CG2 4.46Å; F9-V13 HydrophobicContact CE1-CG2 3.81Å; F9-V13 HydrophobicContact CE2-CB 4.49Å; F9-V13 HydrophobicContact CE2-CG1 3.72Å; F9-V13 HydrophobicContact CE2-CG2 4.12Å; F9-V13 HydrophobicContact CG-CG2 4.5Å; F9-V13 HydrophobicContact CZ-CG1 4.22Å; F9-V13 HydrophobicContact CZ-CG2 3.77Å; F9-V13 WeakPolarHBondContact O-CG1 3.44Å; F9-V13 VanDerWaalsContact O-CG2 3.28Å; F9-V13 WeakPolarHBondContact O-CG2 3.47Å; F9-V13 PolarHBondContact O-N 2.81Å; F9-F75 HydrophobicContact CZ-CD1 4.49Å; F9-F75 HydrophobicContact CZ-CE1 4.01Å; F9-I76 HydrophobicContact CE2-CD1 3.97Å; F9-I76 HydrophobicContact CE2-CG1 4.46Å; F9-Y78 HydrophobicContact CB-CE1 4.31Å; F9-Y78 HydrophobicContact CB-CE2 4.41Å; F9-Y78 HydrophobicContact CD2-CD1 4.04Å; F9-Y78 AromaticContact CD2-CD2 3.58Å; F9-Y78 HydrophobicContact CD2-CD2 3.58Å; F9-Y78 HydrophobicContact CD2-CE1 4.31Å; F9-Y78 AromaticContact CD2-CE2 3.86Å; F9-Y78 HydrophobicContact CD2-CE2 3.86Å; F9-Y78 AromaticContact CD2-CG 3.64Å; F9-Y78 HydrophobicContact CD2-CG 3.64Å; F9-Y78 HydrophobicContact CE2-CD2 4.12Å; F9-Y78 HydrophobicContact CE2-CG 4.13Å; F9-F113 HydrophobicContact CB-CD2 4.26Å; F9-F113 HydrophobicContact CB-CE2 3.8Å; F9-F113 HydrophobicContact CD2-CD2 4.2Å; F9-F113 HydrophobicContact CG-CD2 4.34Å; F9-F113 HydrophobicContact CG-CE2 4.29Å; F9-L116 HydrophobicContact CD2-CD1 4.28Å; F9-L116 HydrophobicContact CE2-CD1 3.31Å; F9-L116 HydrophobicContact CZ-CD1 3.54Å; F9-I160 HydrophobicContact CE1-CG2 4.28Å; F9-I160 HydrophobicContact CZ-CG2 4.02Å; F9-I216 HydrophobicContact CD1-CD1 3.81Å; F9-I216 HydrophobicContact CD1-CG1 4.37Å; F9-I216 HydrophobicContact CD2-CD1 4.26Å; F9-I216 HydrophobicContact CE1-CD1 3.58Å; F9-I216 HydrophobicContact CE1-CG1 4.09Å; F9-I216 HydrophobicContact CE2-CD1 4.04Å; F9-I216 HydrophobicContact CG-CD1 4.15Å; F9-I216 HydrophobicContact CZ-CD1 3.7Å; F9-A217 HydrophobicContact CD1-CB 4.46Å; F9-A217 HydrophobicContact CE1-CB 4.16Å
10V88.2Confident81.9Confident15 Ų1558.6 Ų58.69%0.09130%0.303CS..Hα-helixtrans-59.6-41.3-179.9171.10000111.4T6 K7 N8 E12 V13 D14 L19 P21 A217T6-V10 WeakPolarHBondContact O-CG2 3.3Å; T6-V10 PolarHBondContact O-N 2.93Å; K7-V10 PolarHBondContact O-N 3.2Å; N8-V10 PolarHBondContact O-N 3.31Å; V10-E12 VanDerWaalsContact C-N 3.25Å; V10-E12 PolarHBondContact O-N 2.71Å; V10-V13 PolarHBondContact O-N 2.84Å; V10-D14 HydrophobicContact CG1-CB 4.4Å; V10-D14 PolarHBondContact O-N 2.9Å; V10-L19 HydrophobicContact CG1-CB 4.1Å; V10-L19 WeakPolarHBondContact CG1-O 3.45Å; V10-L19 HydrophobicContact CG2-CB 4.35Å; V10-P21 HydrophobicContact CB-CB 4.43Å; V10-P21 HydrophobicContact CG2-CB 3.9Å; V10-A217 HydrophobicContact CG2-CB 3.64Å
11K81.6Confident82.4Confident147 Ų14757.6 Ų57.664%0.63930%0.3SS*.Hα-helixtrans-58.4-36.4178.1-173.4-177.6178.5-1760112.5K7 N8 F9K7-K11 WeakPolarHBondContact O-CB 3.33Å; K7-K11 PolarHBondContact O-N 3.31Å; N8-K11 WeakPolarHBondContact O-CB 3.49Å; N8-K11 PolarHBondContact O-N 3.45Å; F9-K11 VanDerWaalsContact C-N 3.29Å; F9-K11 PolarHBondContact O-N 3.43Å
12E82.8Confident83.1Confident121 Ų12155.3 Ų55.357%0.56529%0.288SS*.Hα-helixtrans-82.7-35.4-179-70.3-177.9-162.800113.3N8 F9 V10 Y78N8-E12 PolarHBondContact O-N 3.44Å; N8-E12 VanDerWaalsContact O-N 3.12Å; F9-E12 PolarHBondContact O-N 2.85Å; F9-E12 VanDerWaalsContact O-N 3.14Å; V10-E12 VanDerWaalsContact C-N 3.25Å; V10-E12 PolarHBondContact O-N 2.71Å; E12-Y78 WeakPolarHBondContact OE2-CE2 3.35Å
13V84.3Confident83.2Confident43 Ų4358.8 Ų58.826%0.26131%0.314SS..Hα-helixtrans-99.5-20.7-167.9-53.10000114.3F9 V10 L19 F75 I76 Y78F9-V13 HydrophobicContact CD1-CG2 4.2Å; F9-V13 HydrophobicContact CD2-CG1 3.92Å; F9-V13 HydrophobicContact CD2-CG2 4.46Å; F9-V13 HydrophobicContact CE1-CG2 3.81Å; F9-V13 HydrophobicContact CE2-CB 4.49Å; F9-V13 HydrophobicContact CE2-CG1 3.72Å; F9-V13 HydrophobicContact CE2-CG2 4.12Å; F9-V13 HydrophobicContact CG-CG2 4.5Å; F9-V13 HydrophobicContact CZ-CG1 4.22Å; F9-V13 HydrophobicContact CZ-CG2 3.77Å; F9-V13 WeakPolarHBondContact O-CG1 3.44Å; F9-V13 VanDerWaalsContact O-CG2 3.28Å; F9-V13 WeakPolarHBondContact O-CG2 3.47Å; F9-V13 PolarHBondContact O-N 2.81Å; V10-V13 PolarHBondContact O-N 2.84Å; V13-L19 HydrophobicContact CG2-CD1 4.5Å; V13-F75 HydrophobicContact CG2-CE1 4.5Å; V13-I76 HydrophobicContact CB-CD1 4.25Å; V13-I76 HydrophobicContact CG1-CD1 3.47Å; V13-I76 VanDerWaalsContact CG1-CD1 3.47Å; V13-Y78 HydrophobicContact CG1-CD2 4.42Å
14D83.8Confident83.3Confident26 Ų2658.9 Ų58.914%0.13931%0.312CS..  trans-119.989.1-175.6-178.624.5000112.5V10 R16 G17 L18 L19V10-D14 HydrophobicContact CG1-CB 4.4Å; V10-D14 PolarHBondContact O-N 2.9Å; D14-R16 PolarHBondContact O-N 3.34Å; D14-R16 PolarHBondContact OD1-N 2.82Å; D14-G17 PolarHBondContact O-N 2.87Å; D14-G17 PolarHBondContact OD1-N 2.74Å; D14-G17 WeakPolarHBondContact OD2-CA 3.12Å; D14-G17 PolarHBondContact OD2-N 2.98Å; D14-L18 PolarHBondContact OD2-N 3.31Å; D14-L19 HydrophobicContact CB-CB 4.18Å; D14-L19 HydrophobicContact CB-CD1 4.11Å; D14-L19 HydrophobicContact CB-CG 4.24Å; D14-L19 WeakPolarHBondContact OD2-CB 3.49Å; D14-L19 PolarHBondContact OD2-N 2.88Å
15N64.1Low83.5Confident132 Ų13258.6 Ų58.671%0.70631%0.311SS*.THydrogen-bonded Turntrans-69.8-13174.366.29.5000113.9
16R65.5Low83.4Confident201 Ų20165.7 Ų65.776%0.75835%0.349SS*.THydrogen-bonded Turntrans-92.7-14.3-179-59.1-166.6176.6-159.5-1.3112.7D14 L18D14-R16 PolarHBondContact O-N 3.34Å; D14-R16 PolarHBondContact OD1-N 2.82Å; R16-L18 VanDerWaalsContact C-N 3.34Å; R16-L18 HydrophobicContact CB-CD1 4.04Å; R16-L18 HydrophobicContact CB-CG 3.93Å
17G75.1Confident83.1Confident65 Ų6568.3 Ų68.367%0.6736%0.363SS*.SBendtrans65.634.4179.100000113.6D14D14-G17 PolarHBondContact O-N 2.87Å; D14-G17 PolarHBondContact OD1-N 2.74Å; D14-G17 WeakPolarHBondContact OD2-CA 3.12Å; D14-G17 PolarHBondContact OD2-N 2.98Å
18L84.4Confident82.8Confident103 Ų10368.9 Ų68.954%0.53937%0.371SS..  trans-94.2-29.1178-61.6177.9000112.6D14 R16D14-L18 PolarHBondContact OD2-N 3.31Å; R16-L18 VanDerWaalsContact C-N 3.34Å; R16-L18 HydrophobicContact CB-CD1 4.04Å; R16-L18 HydrophobicContact CB-CG 3.93Å
19L92Very high83.3Confident22 Ų2268.4 Ų68.412%0.11537%0.368CS..  trans-81.1139.2176.1-65.5-176.2000110.4V10 V13 D14 E158 I160 A217V10-L19 HydrophobicContact CG1-CB 4.1Å; V10-L19 WeakPolarHBondContact CG1-O 3.45Å; V10-L19 HydrophobicContact CG2-CB 4.35Å; V13-L19 HydrophobicContact CG2-CD1 4.5Å; D14-L19 HydrophobicContact CB-CB 4.18Å; D14-L19 HydrophobicContact CB-CD1 4.11Å; D14-L19 HydrophobicContact CB-CG 4.24Å; D14-L19 WeakPolarHBondContact OD2-CB 3.49Å; D14-L19 PolarHBondContact OD2-N 2.88Å; L19-E158 HydrophobicContact CD2-CG 4.39Å; L19-I160 HydrophobicContact CD1-CG1 4.11Å; L19-A217 HydrophobicContact CB-CB 4.42Å
20I92.6Very high83.5Confident19 Ų1972.2 Ų72.210%0.09739%0.386CS..EExtended strand (participates in β ladder)trans-112125.6177.8-57.4159.3000106.8Y49 A217 Y218 I220I20-Y49 HydrophobicContact CB-CD2 4.46Å; I20-Y49 HydrophobicContact CD1-CD1 3.84Å; I20-Y49 HydrophobicContact CD1-CD2 3.71Å; I20-Y49 HydrophobicContact CD1-CE1 3.73Å; I20-Y49 HydrophobicContact CD1-CE2 3.55Å; I20-Y49 HydrophobicContact CD1-CG 3.83Å; I20-Y49 HydrophobicContact CG1-CD2 3.98Å; I20-Y49 HydrophobicContact CG1-CE2 3.7Å; I20-Y49 HydrophobicContact CG2-CD2 3.62Å; I20-Y49 HydrophobicContact CG2-CE2 4.12Å; I20-Y49 HydrophobicContact CG2-CG 4.25Å; I20-A217 CarbonylContact O-C 3.51Å; I20-A217 VanDerWaalsContact O-CA 3.25Å; I20-A217 WeakPolarHBondContact O-CA 3.48Å; I20-Y218 HydrophobicContact CB-CD1 4.25Å; I20-Y218 HydrophobicContact CB-CD2 4.45Å; I20-Y218 HydrophobicContact CB-CE1 3.84Å; I20-Y218 HydrophobicContact CB-CE2 4.08Å; I20-Y218 HydrophobicContact CD1-CD2 4.33Å; I20-Y218 HydrophobicContact CD1-CE2 3.77Å; I20-Y218 HydrophobicContact CG2-CE1 3.67Å; I20-Y218 HydrophobicContact CG2-CE2 4.26Å; I20-Y218 WeakPolarHBondContact CG2-OH 3.39Å; I20-Y218 PolarHBondContact N-O 2.78Å; I20-Y218 VanDerWaalsContact O-CD1 3.32Å; I20-Y218 WeakPolarHBondContact O-CD1 3.39Å; I20-Y218 PolarHBondContact O-N 3.32Å; I20-I220 HydrophobicContact CD1-CD1 4.09Å; I20-I220 HydrophobicContact CD1-CG1 3.98Å; I20-I220 HydrophobicContact CD1-CG2 4.1Å
21P91.8Very high83.8Confident37 Ų3772.2 Ų72.224%0.2439%0.385CS..EExtended strand (participates in β ladder)trans-69.1140.4178.228.8-34.1000110.7V10V10-P21 HydrophobicContact CB-CB 4.43Å; V10-P21 HydrophobicContact CG2-CB 3.9Å
22V91.4Very high84.5Confident2 Ų265.3 Ų65.31%0.01236%0.355CS..  trans-76.4130.2172-178.60000109.1F2 T6 S24 D27 M29 T215 I216 Y218F2-V22 HydrophobicContact CE1-CB 4.23Å; F2-V22 HydrophobicContact CE1-CG1 4.01Å; T6-V22 WeakPolarHBondContact CB-O 3.27Å; T6-V22 PolarHBondContact OG1-O 3.03Å; V22-S24 WeakPolarHBondContact CG1-O 3.32Å; V22-D27 HydrophobicContact CG1-CB 4.21Å; V22-M29 HydrophobicContact CG1-CE 4.44Å; V22-M29 HydrophobicContact CG2-CE 4.34Å; V22-M29 HydrophobicContact CG2-CG 4.07Å; V22-T215 HydrophobicContact CG2-CG2 3.87Å; V22-T215 WeakPolarHBondContact CG2-O 3.42Å; V22-I216 PolarHBondContact N-O 3.15Å; V22-Y218 HydrophobicContact CG2-CD1 3.76Å; V22-Y218 HydrophobicContact CG2-CE1 4.22Å
23S84.7Confident85.1Confident84 Ų8459.8 Ų59.859%0.58733%0.33SS*.  trans-92.2-31.1-175.5-63.10000112.7A3A3-S23 WeakPolarHBondContact CB-O 3.34Å
24S84.6Confident85.7Confident42 Ų4257.7 Ų57.729%0.29432%0.317SS..  trans-127.9142.1-179.4178.90000111.9V22 N26 D27V22-S24 WeakPolarHBondContact CG1-O 3.32Å; S24-N26 PolarHBondContact O-N 2.93Å; S24-N26 PolarHBondContact OG-N 3.03Å; S24-D27 WeakPolarHBondContact CB-OD2 3.41Å; S24-D27 PolarHBondContact N-OD2 3.37Å; S24-D27 PolarHBondContact O-N 2.8Å
25L82.4Confident86.2Confident69 Ų6956.5 Ų56.536%0.36131%0.31SS..THydrogen-bonded Turntrans-65.1-19.2171.7-73.5170.2000112.8F2 D27 M208 I210 T214F2-L25 HydrophobicContact CD1-CD2 4.16Å; F2-L25 HydrophobicContact CD1-CG 3.96Å; F2-L25 HydrophobicContact CD2-CD2 3.68Å; F2-L25 HydrophobicContact CD2-CG 4.02Å; F2-L25 HydrophobicContact CE1-CD2 3.9Å; F2-L25 HydrophobicContact CE1-CG 4.1Å; F2-L25 HydrophobicContact CE2-CD2 3.4Å; F2-L25 VanDerWaalsContact CE2-CD2 3.4Å; F2-L25 HydrophobicContact CE2-CG 4.18Å; F2-L25 HydrophobicContact CG-CD2 4.06Å; F2-L25 HydrophobicContact CG-CG 3.91Å; F2-L25 HydrophobicContact CZ-CD2 3.52Å; F2-L25 HydrophobicContact CZ-CG 4.22Å; L25-D27 VanDerWaalsContact C-N 3.33Å; L25-M208 HydrophobicContact CD1-SD 4.12Å; L25-I210 HydrophobicContact CD2-CG2 4.4Å; L25-T214 HydrophobicContact CD2-CG2 3.62Å
26N82.1Confident87.5Confident150 Ų15050.6 Ų50.680%0.80228%0.279SS*.THydrogen-bonded Turntrans-82.8-12.8178.3-63-23.5000112.7S24 N28S24-N26 PolarHBondContact O-N 2.93Å; S24-N26 PolarHBondContact OG-N 3.03Å; N26-N28 PolarHBondContact O-N 3.22Å
27D81.4Confident88.7Confident54 Ų5442.9 Ų42.929%0.28925%0.251SS..  trans-74113.6-177.1-61.5-22000109.6V22 S24 L25 M29V22-D27 HydrophobicContact CG1-CB 4.21Å; S24-D27 WeakPolarHBondContact CB-OD2 3.41Å; S24-D27 PolarHBondContact N-OD2 3.37Å; S24-D27 PolarHBondContact O-N 2.8Å; L25-D27 VanDerWaalsContact C-N 3.33Å; D27-M29 HydrophobicContact CB-CE 3.87Å; D27-M29 HydrophobicContact CB-CG 4.38Å; D27-M29 PolarHBondContact O-N 3.46Å; D27-M29 VanDerWaalsContact O-N 3.16Å
28N77.5Confident89.2Confident102 Ų10241.4 Ų41.455%0.54523%0.227SC..  trans-80.998178.4-170.825.8000111.5N26 E30 T33N26-N28 PolarHBondContact O-N 3.22Å; N28-E30 PolarHBondContact O-N 3.25Å; N28-E30 WeakPolarHBondContact OD1-CG 3.31Å; N28-T33 PolarHBondContact O-OG1 2.87Å
29M91.4Very high88.7Confident2 Ų241.3 Ų41.31%0.0122%0.222CC..  trans-100.961.4-177.1-59.5-69.4-163.200111.5V22 D27 P51 R159 T215 Y218V22-M29 HydrophobicContact CG1-CE 4.44Å; V22-M29 HydrophobicContact CG2-CE 4.34Å; V22-M29 HydrophobicContact CG2-CG 4.07Å; D27-M29 HydrophobicContact CB-CE 3.87Å; D27-M29 HydrophobicContact CB-CG 4.38Å; D27-M29 PolarHBondContact O-N 3.46Å; D27-M29 VanDerWaalsContact O-N 3.16Å; M29-P51 HydrophobicContact CE-CB 3.96Å; M29-P51 HydrophobicContact CE-CG 3.14Å; M29-P51 HydrophobicContact SD-CB 4.03Å; M29-P51 HydrophobicContact SD-CG 3.84Å; M29-R159 WeakPolarHBondContact O-CD 3.38Å; M29-R159 PolarHBondContact O-NH1 2.97Å; M29-R159 VanDerWaalsContact O-NH1 3.17Å; M29-T215 HydrophobicContact CB-CG2 3.78Å; M29-T215 HydrophobicContact CG-CG2 4.42Å; M29-Y218 HydrophobicContact CE-CD1 3.79Å; M29-Y218 HydrophobicContact CE-CE1 3.27Å; M29-Y218 HydrophobicContact CE-CE2 4.41Å; M29-Y218 HydrophobicContact CG-CD1 4.28Å; M29-Y218 HydrophobicContact SD-CD1 4.02Å; M29-Y218 HydrophobicContact SD-CD2 4.41Å; M29-Y218 HydrophobicContact SD-CE1 3.98Å; M29-Y218 HydrophobicContact SD-CE2 4.35Å; M29-Y218 HydrophobicContact SD-CG 4.24Å
30E92.4Very high87.9Confident80 Ų8045.9 Ų45.937%0.37424%0.238SC..  trans-74.6162.2170.3-70.6-61.1138.200111.5N28 T33 V156 R159N28-E30 PolarHBondContact O-N 3.25Å; N28-E30 WeakPolarHBondContact OD1-CG 3.31Å; E30-T33 PolarHBondContact N-OG1 3.32Å; E30-T33 WeakPolarHBondContact O-CB 3.31Å; E30-T33 PolarHBondContact O-N 2.97Å; E30-T33 PolarHBondContact O-OG1 3.1Å; E30-T33 VanDerWaalsContact O-OG1 3.09Å; E30-V156 VanDerWaalsContact O-CB 3.31Å; E30-V156 WeakPolarHBondContact O-CB 3.22Å; E30-R159 VanDerWaalsContact CD-NH2 3.31Å; E30-R159 IonicContact OE1-CZ 2.54Å; E30-R159 IonicContact OE1-NH1 3.37Å; E30-R159 PolarHBondContact OE1-NH1 3.09Å; E30-R159 IonicContact OE1-NH2 2.68Å; E30-R159 PolarHBondContact OE1-NH2 3Å; E30-R159 IonicContact OE2-CZ 3.19Å; E30-R159 IonicContact OE2-NH1 2.78Å; E30-R159 PolarHBondContact OE2-NH1 3.42Å; E30-R159 IonicContact OE2-NH2 2.72Å; E30-R159 PolarHBondContact OE2-NH2 2.7Å
31L94.8Very high87.1Confident15 Ų1546.7 Ų46.78%0.07925%0.245CC..THydrogen-bonded Turntrans-64.1141.9172.5-68.1174.7000109.7T33 P68 V70 A121 V156 K157L31-T33 PolarHBondContact O-N 3.21Å; L31-P68 HydrophobicContact CB-CG 4.26Å; L31-V70 HydrophobicContact CD1-CB 4.12Å; L31-V70 HydrophobicContact CD1-CG1 3.72Å; L31-V70 HydrophobicContact CD1-CG2 3.45Å; L31-V70 VanDerWaalsContact CD1-CG2 3.45Å; L31-A121 HydrophobicContact CD1-CB 4.37Å; L31-A121 HydrophobicContact CD2-CB 4.38Å; L31-V156 HydrophobicContact CD2-CG1 4.33Å; L31-K157 WeakPolarHBondContact CD2-O 3.36Å
32L95.3Very high86.8Confident3 Ų346.5 Ų46.52%0.01624%0.24CC..THydrogen-bonded Turntrans68.13.1-173.1-45.4-178.5000115.7V34 T55 L56 I66 P68 L126 I155 V156L32-V34 PolarHBondContact O-N 2.83Å; L32-T55 CarbonylContact O-C 3.58Å; L32-T55 WeakPolarHBondContact O-CA 3.21Å; L32-L56 HydrophobicContact CB-CB 4.24Å; L32-L56 PolarHBondContact O-N 2.84Å; L32-I66 HydrophobicContact CD1-CG2 4.28Å; L32-P68 HydrophobicContact CD1-CB 4.01Å; L32-P68 HydrophobicContact CD1-CG 3.81Å; L32-P68 HydrophobicContact CD2-CB 4.41Å; L32-P68 HydrophobicContact CG-CB 4.09Å; L32-P68 HydrophobicContact CG-CG 3.99Å; L32-L126 HydrophobicContact CD2-CD1 3.8Å; L32-L126 HydrophobicContact CD2-CD2 3.74Å; L32-L126 HydrophobicContact CD2-CG 4.44Å; L32-I155 HydrophobicContact CD2-CD1 4Å; L32-V156 PolarHBondContact N-O 3.25Å
33T96.3Very high86.3Confident4 Ų450.6 Ų50.63%0.02526%0.257CS..EExtended strand (participates in β ladder)trans-54.7133167.2-67.90000109.4N28 E30 L31 I155 V156N28-T33 PolarHBondContact O-OG1 2.87Å; E30-T33 PolarHBondContact N-OG1 3.32Å; E30-T33 WeakPolarHBondContact O-CB 3.31Å; E30-T33 PolarHBondContact O-N 2.97Å; E30-T33 PolarHBondContact O-OG1 3.1Å; E30-T33 VanDerWaalsContact O-OG1 3.09Å; L31-T33 PolarHBondContact O-N 3.21Å; T33-I155 CarbonylContact O-C 3.55Å; T33-I155 VanDerWaalsContact O-CA 3.3Å; T33-I155 WeakPolarHBondContact O-CA 3.29Å; T33-V156 PolarHBondContact O-N 3.1Å
34V96.2Very high86.1Confident0 Ų046.8 Ų46.80%023%0.23CC..EExtended strand (participates in β ladder)trans-80.5130.7178.1175.20000109.1L32 T52 F54 L59 L141 F153 A154 I155L32-V34 PolarHBondContact O-N 2.83Å; V34-T52 WeakPolarHBondContact O-CB 3.23Å; V34-T52 PolarHBondContact O-N 2.86Å; V34-T52 PolarHBondContact O-OG1 2.78Å; V34-F54 WeakPolarHBondContact CB-O 2.82Å; V34-F54 PolarHBondContact N-O 3.09Å; V34-L59 HydrophobicContact CB-CD1 4.39Å; V34-L59 HydrophobicContact CG1-CD1 4.09Å; V34-L59 HydrophobicContact CG2-CD1 3.69Å; V34-L59 HydrophobicContact CG2-CG 4.3Å; V34-L141 HydrophobicContact CG1-CD2 4.31Å; V34-F153 HydrophobicContact CG1-CD1 3.46Å; V34-F153 VanDerWaalsContact CG1-CD1 3.46Å; V34-F153 HydrophobicContact CG1-CE1 3.82Å; V34-F153 HydrophobicContact CG1-CG 4.34Å; V34-A154 WeakPolarHBondContact CA-O 3.49Å; V34-I155 HydrophobicContact CG2-CG2 4.25Å
35V94.5Very high86Confident0 Ų045.1 Ų45.10%022%0.218CC..EExtended strand (participates in β ladder)trans-121.6130.1178.4-178.40000108.2Y49 A154 V156 Y218 I220V35-Y49 HydrophobicContact CG1-CD1 4.22Å; V35-A154 PolarHBondContact N-O 2.97Å; V35-A154 PolarHBondContact O-N 3.32Å; V35-V156 HydrophobicContact CG2-CG2 3.86Å; V35-Y218 HydrophobicContact CG2-CE2 4.26Å; V35-I220 HydrophobicContact CG2-CG2 4.32Å
36V92.1Very high85.8Confident9 Ų947.2 Ų47.26%0.05522%0.224CC..EExtended strand (participates in β ladder)trans-89.2108.5171.7-177.40000108.7H38 L50 T52 T145 N151 F153V36-H38 PolarHBondContact O-ND1 3.46Å; V36-L50 HydrophobicContact CB-CB 4.45Å; V36-L50 PolarHBondContact N-O 2.77Å; V36-L50 PolarHBondContact O-N 3.02Å; V36-T52 HydrophobicContact CG2-CG2 3.85Å; V36-T145 HydrophobicContact CG1-CG2 4.23Å; V36-N151 HydrophobicContact CG1-CB 3.85Å; V36-F153 HydrophobicContact CG2-CD1 4Å; V36-F153 HydrophobicContact CG2-CE1 3.73Å
37K90.5Very high85.9Confident38 Ų3840.8 Ų40.817%0.16519%0.191CC..EExtended strand (participates in β ladder)trans-83120.2170.3-179-174.9-172.6-173.90109.3P47 Y49 V152 E222K37-P47 HydrophobicContact CD-CB 4.37Å; K37-P47 VanDerWaalsContact CE-CB 3.45Å; K37-P47 HydrophobicContact CG-CB 4.01Å; K37-Y49 HydrophobicContact CB-CD1 4Å; K37-Y49 HydrophobicContact CB-CE1 3.99Å; K37-Y49 HydrophobicContact CD-CE1 3.83Å; K37-Y49 HydrophobicContact CG-CD1 4Å; K37-Y49 HydrophobicContact CG-CE1 3.58Å; K37-V152 HydrophobicContact CB-CB 4.38Å; K37-V152 PolarHBondContact N-O 3.4Å; K37-V152 PolarHBondContact O-N 3.13Å; K37-E222 VanDerWaalsContact CD-OE1 3.26Å; K37-E222 WeakPolarHBondContact CD-OE1 3.46Å; K37-E222 WeakPolarHBondContact CE-OE1 3.42Å; K37-E222 IonicContact NZ-OE1 3.62Å; K37-E222 PolarHBondContact NZ-OE1 2.95Å
38H83.9Confident86Confident35 Ų3541 Ų4116%0.16219%0.189CC..EExtended strand (participates in β ladder)trans-84.8122.3171.6-66.663.4000108.4V36 K48 L50 N151V36-H38 PolarHBondContact O-ND1 3.46Å; H38-K48 HydrophobicContact CB-CB 4.42Å; H38-K48 PolarHBondContact N-O 3.38Å; H38-L50 WeakPolarHBondContact CE1-CD1 3.46Å; H38-N151 PolarHBondContact CD2-OD1 3.21Å; H38-N151 PolarHBondContact NE2-ND2 3.17Å; H38-N151 PolarHBondContact NE2-OD1 2.67Å
39K74.3Confident86.5Confident100 Ų10038.9 Ų38.944%0.43517%0.174SC..PPolyproline II helixtrans-60.3141.6173.4-73.9180-176.7173.90108.7S41 K150 V152K39-S41 PolarHBondContact O-N 2.86Å; K39-K150 WeakPolarHBondContact CA-O 2.91Å; K39-K150 HydrophobicContact CB-CB 4.2Å; K39-K150 WeakPolarHBondContact CB-O 3.27Å; K39-K150 WeakPolarHBondContact CG-O 3.39Å; K39-K150 PolarHBondContact N-O 3.46Å; K39-V152 HydrophobicContact CD-CG2 4.38Å; K39-V152 VanDerWaalsContact CE-CG2 3.42Å; K39-V152 HydrophobicContact CG-CG2 4.16Å
40R75.3Confident86.3Confident119 Ų11943.3 Ų43.345%0.44920%0.197SC..PPolyproline II helixtrans-59.5133.3-178.8-51.3166175.5-166.7-1.3109.2W42 F43 Q45 P47R40-W42 VanDerWaalsContact C-N 3.28Å; R40-W42 WeakPolarHBondContact CB-O 3.47Å; R40-F43 PolarHBondContact NH1-O 3.37Å; R40-Q45 HydrophobicContact CB-CB 4.31Å; R40-Q45 WeakPolarHBondContact CD-O 3.41Å; R40-Q45 VanDerWaalsContact CG-O 3.27Å; R40-Q45 WeakPolarHBondContact CG-O 3.33Å; R40-Q45 VanDerWaalsContact CZ-O 3.25Å; R40-Q45 PolarHBondContact NE-O 2.94Å; R40-P47 HydrophobicContact CG-CG 4.13Å
41S76.9Confident86.2Confident36 Ų3641.5 Ų41.525%0.25219%0.192SC..SBendtrans-69-35.7169.9-71.60000110.1K39 H357K39-S41 PolarHBondContact O-N 2.86Å; S41-H357 VanDerWaalsContact CB-CE1 3.41Å; S41-H357 WeakPolarHBondContact CB-CE1 3.31Å
42W84.3Confident86.1Confident32 Ų3241.8 Ų41.812%0.12120%0.195CC..SBendtrans-121143.9174.6-52.2112.3000111.8R40 W44 Q45 L269 H272 T354 H357 L358 S361R40-W42 VanDerWaalsContact C-N 3.28Å; R40-W42 WeakPolarHBondContact CB-O 3.47Å; W42-W44 HydrophobicContact CB-CD2 3.78Å; W42-W44 VanDerWaalsContact CB-CE2 3.47Å; W42-W44 HydrophobicContact CB-CE3 3.96Å; W42-W44 HydrophobicContact CB-CG 4.5Å; W42-W44 HydrophobicContact CB-CH2 3.58Å; W42-W44 HydrophobicContact CB-CZ2 3.39Å; W42-W44 HydrophobicContact CB-CZ3 3.87Å; W42-W44 AromaticContact CD2-CH2 3.76Å; W42-W44 HydrophobicContact CD2-CH2 3.76Å; W42-W44 AromaticContact CD2-CZ2 3.86Å; W42-W44 HydrophobicContact CD2-CZ2 3.86Å; W42-W44 AromaticContact CE3-CH2 3.67Å; W42-W44 HydrophobicContact CE3-CH2 3.67Å; W42-W44 HydrophobicContact CE3-CZ2 4.26Å; W42-W44 HydrophobicContact CE3-CZ3 4.34Å; W42-W44 AromaticContact CG-CE2 3.97Å; W42-W44 AromaticContact CG-CH2 3.73Å; W42-W44 HydrophobicContact CG-CH2 3.73Å; W42-W44 AromaticContact CG-CZ2 3.46Å; W42-W44 HydrophobicContact CG-CZ2 3.46Å; W42-W44 VanDerWaalsContact CG-CZ2 3.46Å; W42-W44 HydrophobicContact CG-CZ3 4.47Å; W42-W44 PolarHBondContact O-N 2.86Å; W42-Q45 HydrophobicContact CB-CG 4.09Å; W42-Q45 PolarHBondContact O-N 3.24Å; W42-Q45 VanDerWaalsContact O-N 3.07Å; W42-L269 HydrophobicContact CE3-CD2 4.43Å; W42-L269 HydrophobicContact CZ3-CD2 4.18Å; W42-H272 AromaticContact CH2-NE2 3.64Å; W42-T354 HydrophobicContact CH2-CG2 3.76Å; W42-T354 HydrophobicContact CZ2-CG2 4.11Å; W42-H357 AromaticContact CD1-CE1 3.91Å; W42-H357 AromaticContact CD1-ND1 3.99Å; W42-H357 AromaticContact CE2-ND1 3.61Å; W42-H357 AromaticContact CZ2-ND1 3.81Å; W42-H357 AromaticContact NE1-CE1 3.36Å; W42-H357 PolarHBondContact NE1-CE1 2.9Å; W42-H357 AromaticContact NE1-ND1 3.01Å; W42-H357 PolarHBondContact NE1-ND1 3.02Å; W42-L358 HydrophobicContact CD2-CD1 3.75Å; W42-L358 HydrophobicContact CE3-CD1 3.89Å; W42-L358 HydrophobicContact CG-CD1 4.4Å; W42-L358 HydrophobicContact CH2-CB 4.19Å; W42-L358 HydrophobicContact CH2-CD1 3.87Å; W42-L358 HydrophobicContact CZ2-CB 3.63Å; W42-L358 HydrophobicContact CZ2-CD1 3.73Å; W42-L358 HydrophobicContact CZ2-CG 4.33Å; W42-L358 HydrophobicContact CZ3-CD1 3.95Å; W42-S361 VanDerWaalsContact CD1-CB 3.43Å; W42-S361 PolarHBondContact NE1-OG 3.18Å
43F81.5Confident85.9Confident88 Ų8849.4 Ų49.439%0.38624%0.235SC..THydrogen-bonded Turntrans-61.4-25.2-172.269.2-96.2000114R40 E265 L445R40-F43 PolarHBondContact NH1-O 3.37Å; F43-E265 HydrophobicContact CE1-CB 4.31Å; F43-E265 HydrophobicContact CE1-CG 4.19Å; F43-E265 WeakPolarHBondContact CE1-OE2 3.43Å; F43-E265 HydrophobicContact CE2-CG 4.11Å; F43-E265 HydrophobicContact CZ-CB 3.71Å; F43-E265 VanDerWaalsContact CZ-CD 3.47Å; F43-E265 HydrophobicContact CZ-CG 3.45Å; F43-E265 VanDerWaalsContact CZ-CG 3.45Å; F43-E265 WeakPolarHBondContact CZ-OE2 3.2Å; F43-L445 HydrophobicContact CE2-CD2 3.57Å; F43-L445 HydrophobicContact CZ-CD2 3.56Å
44W81.4Confident85.8Confident5 Ų552.7 Ų52.72%0.01925%0.249CC..THydrogen-bonded Turntrans-84.9-18.5179.16085.1000114.6W42 L269 L358 N442 I446 I449W42-W44 HydrophobicContact CB-CD2 3.78Å; W42-W44 VanDerWaalsContact CB-CE2 3.47Å; W42-W44 HydrophobicContact CB-CE3 3.96Å; W42-W44 HydrophobicContact CB-CG 4.5Å; W42-W44 HydrophobicContact CB-CH2 3.58Å; W42-W44 HydrophobicContact CB-CZ2 3.39Å; W42-W44 HydrophobicContact CB-CZ3 3.87Å; W42-W44 AromaticContact CD2-CH2 3.76Å; W42-W44 HydrophobicContact CD2-CH2 3.76Å; W42-W44 AromaticContact CD2-CZ2 3.86Å; W42-W44 HydrophobicContact CD2-CZ2 3.86Å; W42-W44 AromaticContact CE3-CH2 3.67Å; W42-W44 HydrophobicContact CE3-CH2 3.67Å; W42-W44 HydrophobicContact CE3-CZ2 4.26Å; W42-W44 HydrophobicContact CE3-CZ3 4.34Å; W42-W44 AromaticContact CG-CE2 3.97Å; W42-W44 AromaticContact CG-CH2 3.73Å; W42-W44 HydrophobicContact CG-CH2 3.73Å; W42-W44 AromaticContact CG-CZ2 3.46Å; W42-W44 HydrophobicContact CG-CZ2 3.46Å; W42-W44 VanDerWaalsContact CG-CZ2 3.46Å; W42-W44 HydrophobicContact CG-CZ3 4.47Å; W42-W44 PolarHBondContact O-N 2.86Å; W44-L269 HydrophobicContact CH2-CD1 3.47Å; W44-L269 VanDerWaalsContact CH2-CD1 3.47Å; W44-L269 HydrophobicContact CH2-CD2 3.8Å; W44-L269 HydrophobicContact CH2-CG 4.26Å; W44-L269 HydrophobicContact CZ2-CD1 4.38Å; W44-L269 HydrophobicContact CZ3-CD1 3.69Å; W44-L269 HydrophobicContact CZ3-CD2 4.14Å; W44-L269 HydrophobicContact CZ3-CG 4.43Å; W44-L358 HydrophobicContact CH2-CD1 3.29Å; W44-L358 HydrophobicContact CZ2-CD1 3.29Å; W44-L358 HydrophobicContact CZ2-CG 4.5Å; W44-N442 HydrophobicContact CB-CB 4.1Å; W44-I446 HydrophobicContact CB-CD1 4.41Å; W44-I446 HydrophobicContact CB-CG1 4.07Å; W44-I446 HydrophobicContact CG-CG1 4.01Å; W44-I449 HydrophobicContact CD2-CD1 3.77Å; W44-I449 HydrophobicContact CE3-CD1 3.86Å; W44-I449 HydrophobicContact CH2-CD1 3.86Å; W44-I449 HydrophobicContact CZ2-CD1 3.73Å; W44-I449 HydrophobicContact CZ2-CG2 4.35Å; W44-I449 HydrophobicContact CZ3-CD1 3.91Å
45Q81.1Confident85.8Confident7 Ų754.6 Ų54.63%0.03326%0.261CS..SBendtrans-66.3151.5-179.7-78.1-178.7-59.800111.7R40 W42 S361 E365R40-Q45 HydrophobicContact CB-CB 4.31Å; R40-Q45 WeakPolarHBondContact CD-O 3.41Å; R40-Q45 VanDerWaalsContact CG-O 3.27Å; R40-Q45 WeakPolarHBondContact CG-O 3.33Å; R40-Q45 VanDerWaalsContact CZ-O 3.25Å; R40-Q45 PolarHBondContact NE-O 2.94Å; W42-Q45 HydrophobicContact CB-CG 4.09Å; W42-Q45 PolarHBondContact O-N 3.24Å; W42-Q45 VanDerWaalsContact O-N 3.07Å; Q45-S361 PolarHBondContact NE2-OG 3.36Å; Q45-E365 WeakPolarHBondContact CA-OE1 3.46Å; Q45-E365 HydrophobicContact CG-CG 4.11Å
46K79.6Confident85.8Confident112 Ų11254.6 Ų54.649%0.48726%0.261SS..PPolyproline II helixtrans-73.6138.2166.8-69.2170.9-171.8169.90108.7E365 Y443K46-E365 WeakPolarHBondContact CB-OE1 3.3Å; K46-E365 WeakPolarHBondContact CD-OE2 3.36Å; K46-E365 WeakPolarHBondContact CG-OE2 3.38Å; K46-E365 PolarHBondContact N-OE1 2.73Å; K46-Y443 PolarHBondContact NZ-OH 3.44Å
47P83.3Confident86Confident16 Ų1656.2 Ų56.210%0.10427%0.269CS..PPolyproline II helixtrans-61.8143.1171.9-15.328.9000110.1K37 R40 Y49K37-P47 HydrophobicContact CD-CB 4.37Å; K37-P47 VanDerWaalsContact CE-CB 3.45Å; K37-P47 HydrophobicContact CG-CB 4.01Å; R40-P47 HydrophobicContact CG-CG 4.13Å; P47-Y49 HydrophobicContact CB-CE1 4.31Å; P47-Y49 HydrophobicContact CB-CE2 4.13Å; P47-Y49 WeakPolarHBondContact O-CD2 3.44Å; P47-Y49 VanDerWaalsContact O-CE2 3.31Å; P47-Y49 WeakPolarHBondContact O-CE2 3.3Å
48K84.1Confident86.2Confident58 Ų5858.5 Ų58.525%0.25228%0.283SS..EExtended strand (participates in β ladder)trans-92.6137.2171-65.3-174.8176.1-176.50109.6H38 N306 D309H38-K48 HydrophobicContact CB-CB 4.42Å; H38-K48 PolarHBondContact N-O 3.38Å; K48-N306 PolarHBondContact NZ-OD1 3.26Å; K48-D309 IonicContact NZ-OD2 2.84Å; K48-D309 PolarHBondContact NZ-OD2 2.76Å
49Y87.7Confident86.7Confident58 Ų5856.8 Ų56.823%0.22728%0.276CS..EExtended strand (participates in β ladder)trans-116.2123.6-177.5-59.5-78.5000108.9I20 V35 K37 P47 Y218 I220I20-Y49 HydrophobicContact CB-CD2 4.46Å; I20-Y49 HydrophobicContact CD1-CD1 3.84Å; I20-Y49 HydrophobicContact CD1-CD2 3.71Å; I20-Y49 HydrophobicContact CD1-CE1 3.73Å; I20-Y49 HydrophobicContact CD1-CE2 3.55Å; I20-Y49 HydrophobicContact CD1-CG 3.83Å; I20-Y49 HydrophobicContact CG1-CD2 3.98Å; I20-Y49 HydrophobicContact CG1-CE2 3.7Å; I20-Y49 HydrophobicContact CG2-CD2 3.62Å; I20-Y49 HydrophobicContact CG2-CE2 4.12Å; I20-Y49 HydrophobicContact CG2-CG 4.25Å; V35-Y49 HydrophobicContact CG1-CD1 4.22Å; K37-Y49 HydrophobicContact CB-CD1 4Å; K37-Y49 HydrophobicContact CB-CE1 3.99Å; K37-Y49 HydrophobicContact CD-CE1 3.83Å; K37-Y49 HydrophobicContact CG-CD1 4Å; K37-Y49 HydrophobicContact CG-CE1 3.58Å; P47-Y49 HydrophobicContact CB-CE1 4.31Å; P47-Y49 HydrophobicContact CB-CE2 4.13Å; P47-Y49 WeakPolarHBondContact O-CD2 3.44Å; P47-Y49 VanDerWaalsContact O-CE2 3.31Å; P47-Y49 WeakPolarHBondContact O-CE2 3.3Å; Y49-Y218 VanDerWaalsContact CB-OH 3.31Å; Y49-Y218 WeakPolarHBondContact CB-OH 3.4Å; Y49-I220 HydrophobicContact CD1-CD1 3.84Å; Y49-I220 HydrophobicContact CE1-CD1 3.36Å
50L87.6Confident87.7Confident95 Ų9552.8 Ų52.850%0.49726%0.259SS..EExtended strand (participates in β ladder)trans-112.4105.5175.2-62.7-173.6000108.6V36 H38V36-L50 HydrophobicContact CB-CB 4.45Å; V36-L50 PolarHBondContact N-O 2.77Å; V36-L50 PolarHBondContact O-N 3.02Å; H38-L50 WeakPolarHBondContact CE1-CD1 3.46Å
51P89.9Confident88.4Confident41 Ų4149.3 Ų49.327%0.26626%0.256SS..EExtended strand (participates in β ladder)trans-58.8150.4169.6-20.234.4000110.1M29M29-P51 HydrophobicContact CE-CB 3.96Å; M29-P51 HydrophobicContact CE-CG 3.14Å; M29-P51 HydrophobicContact SD-CB 4.03Å; M29-P51 HydrophobicContact SD-CG 3.84Å
52T92.1Very high88.6Confident22 Ų2250.3 Ų50.314%0.13527%0.271CS..EExtended strand (participates in β ladder)trans-121.4161.3175.174.80000109.6V34 V36 F54 L141V34-T52 WeakPolarHBondContact O-CB 3.23Å; V34-T52 PolarHBondContact O-N 2.86Å; V34-T52 PolarHBondContact O-OG1 2.78Å; V36-T52 HydrophobicContact CG2-CG2 3.85Å; T52-F54 PolarHBondContact O-N 3.24Å; T52-F54 PolarHBondContact OG1-N 3.39Å; T52-F54 PolarHBondContact OG1-O 3.08Å; T52-L141 HydrophobicContact CG2-CD1 4.24Å; T52-L141 HydrophobicContact CG2-CD2 4.14Å
53D91.8Very high88.3Confident163 Ų16355.8 Ų55.887%0.87230%0.303SS*.EExtended strand (participates in β ladder)trans-762.9175.9-58.3-40.7000112.9
54F94.8Very high88.4Confident72 Ų7255.9 Ų55.932%0.31631%0.312SS..EExtended strand (participates in β ladder)trans-105.9145.3-176.7-58.9-84.3000111.3V34 T52 D58 L59 H139 L141V34-F54 WeakPolarHBondContact CB-O 2.82Å; V34-F54 PolarHBondContact N-O 3.09Å; T52-F54 PolarHBondContact O-N 3.24Å; T52-F54 PolarHBondContact OG1-N 3.39Å; T52-F54 PolarHBondContact OG1-O 3.08Å; F54-D58 HydrophobicContact CB-CB 4.34Å; F54-D58 HydrophobicContact CD1-CB 4.05Å; F54-L59 HydrophobicContact CB-CD2 4.43Å; F54-H139 AromaticContact CD1-CE1 3.87Å; F54-H139 AromaticContact CD1-NE2 3.73Å; F54-H139 AromaticContact CE1-CE1 3.65Å; F54-H139 AromaticContact CE1-NE2 3.5Å; F54-H139 WeakPolarHBondContact CE1-NE2 3.35Å; F54-H139 AromaticContact CZ-CE1 3.83Å; F54-L141 HydrophobicContact CB-CD2 4.31Å; F54-L141 HydrophobicContact CD2-CD2 3.77Å; F54-L141 HydrophobicContact CE2-CD2 4.48Å; F54-L141 HydrophobicContact CG-CD2 4.28Å
55T95.2Very high88.8Confident40 Ų4059.1 Ų59.125%0.24533%0.334CS..EExtended strand (participates in β ladder)trans-98.8167.5168.370.80000110.6L32 N57 D58L32-T55 CarbonylContact O-C 3.58Å; L32-T55 WeakPolarHBondContact O-CA 3.21Å; T55-N57 PolarHBondContact O-N 3.27Å; T55-N57 PolarHBondContact OG1-N 3.27Å; T55-D58 WeakPolarHBondContact CA-OD2 3.28Å; T55-D58 WeakPolarHBondContact CB-OD2 3.5Å; T55-D58 PolarHBondContact N-OD2 3.48Å; T55-D58 PolarHBondContact O-N 3.37Å; T55-D58 VanDerWaalsContact O-N 3.11Å; T55-D58 PolarHBondContact OG1-OD2 2.85Å
56L95.3Very high89.2Confident0 Ų059.1 Ų59.10%033%0.334CS..Hα-helixtrans-53.6-38.1173.6-179.260.3000111.4L32 D58 L59 L60 I66 L135 I155 L223 F231L32-L56 HydrophobicContact CB-CB 4.24Å; L32-L56 PolarHBondContact O-N 2.84Å; L56-D58 VanDerWaalsContact C-N 3.29Å; L56-D58 PolarHBondContact O-N 3.1Å; L56-L59 PolarHBondContact O-N 3.39Å; L56-L59 VanDerWaalsContact O-N 3.1Å; L56-L60 HydrophobicContact CG-CD1 4.4Å; L56-L60 HydrophobicContact CG-CG 4.39Å; L56-L60 WeakPolarHBondContact O-CG 3.49Å; L56-L60 PolarHBondContact O-N 3.4Å; L56-I66 HydrophobicContact CD2-CD1 4.23Å; L56-L135 HydrophobicContact CD1-CD2 4.04Å; L56-I155 HydrophobicContact CB-CG2 4.2Å; L56-I155 HydrophobicContact CD1-CG2 4.43Å; L56-I155 HydrophobicContact CD2-CD1 4.04Å; L56-L223 HydrophobicContact CD1-CD1 4.36Å; L56-F231 HydrophobicContact CD1-CE2 4.22Å; L56-F231 HydrophobicContact CD1-CZ 4.18Å; L56-F231 HydrophobicContact CD2-CE2 4.35Å; L56-F231 HydrophobicContact CD2-CZ 4.37Å
57N95.2Very high89.7Confident43 Ų4358.2 Ų58.223%0.2334%0.338CS..Hα-helixtrans-65-32.9-178.5-71.2-39.4000113.1T55 L59 L60 P65 I66T55-N57 PolarHBondContact O-N 3.27Å; T55-N57 PolarHBondContact OG1-N 3.27Å; N57-L59 PolarHBondContact O-N 3.11Å; N57-L60 PolarHBondContact O-N 3.19Å; N57-P65 HydrophobicContact CB-CB 4.24Å; N57-I66 PolarHBondContact ND2-O 3Å; N57-I66 WeakPolarHBondContact OD1-CB 3.48Å; N57-I66 PolarHBondContact OD1-N 3.05Å
58D94.9Very high89.7Confident86 Ų8659.4 Ų59.446%0.4635%0.346SS..Hα-helixtrans-70.4-21.6177.1-54.4-56.3000112F54 T55 L56F54-D58 HydrophobicContact CB-CB 4.34Å; F54-D58 HydrophobicContact CD1-CB 4.05Å; T55-D58 WeakPolarHBondContact CA-OD2 3.28Å; T55-D58 WeakPolarHBondContact CB-OD2 3.5Å; T55-D58 PolarHBondContact N-OD2 3.48Å; T55-D58 PolarHBondContact O-N 3.37Å; T55-D58 VanDerWaalsContact O-N 3.11Å; T55-D58 PolarHBondContact OG1-OD2 2.85Å; L56-D58 VanDerWaalsContact C-N 3.29Å; L56-D58 PolarHBondContact O-N 3.1Å
59L95.3Very high90Very high0 Ų059.1 Ų59.10%035%0.349CS..Hα-helixtrans-96-8.5178.7-57.5-170.1000113.7V34 F54 L56 N57 L135 D136 H139 L141 I142V34-L59 HydrophobicContact CB-CD1 4.39Å; V34-L59 HydrophobicContact CG1-CD1 4.09Å; V34-L59 HydrophobicContact CG2-CD1 3.69Å; V34-L59 HydrophobicContact CG2-CG 4.3Å; F54-L59 HydrophobicContact CB-CD2 4.43Å; L56-L59 PolarHBondContact O-N 3.39Å; L56-L59 VanDerWaalsContact O-N 3.1Å; N57-L59 PolarHBondContact O-N 3.11Å; L59-L135 HydrophobicContact CB-CD2 3.93Å; L59-L135 CarbonylContact O-C 3.55Å; L59-L135 VanDerWaalsContact O-CA 3.23Å; L59-L135 WeakPolarHBondContact O-CA 3.45Å; L59-D136 PolarHBondContact O-N 3.34Å; L59-H139 HydrophobicContact CD2-CB 4.45Å; L59-H139 VanDerWaalsContact CD2-CE1 3.48Å; L59-H139 WeakPolarHBondContact CD2-CE1 3.26Å; L59-H139 WeakPolarHBondContact CD2-ND1 3.27Å; L59-L141 HydrophobicContact CD1-CD2 4.34Å; L59-L141 HydrophobicContact CD2-CD2 4.28Å; L59-I142 HydrophobicContact CB-CD1 4.21Å; L59-I142 HydrophobicContact CD1-CD1 4.41Å; L59-I142 HydrophobicContact CD1-CG1 4.37Å; L59-I142 HydrophobicContact CD2-CD1 4.44Å; L59-I142 HydrophobicContact CD2-CG1 4.5Å
60L94.9Very high90.2Very high16 Ų1659.6 Ų59.68%0.08436%0.358CS..BIsolated β-bridgetrans-81.3138.4-178.7-75.5174.7000111.4L56 N57 G62 I66 R133 L135 F231L56-L60 HydrophobicContact CG-CD1 4.4Å; L56-L60 HydrophobicContact CG-CG 4.39Å; L56-L60 WeakPolarHBondContact O-CG 3.49Å; L56-L60 PolarHBondContact O-N 3.4Å; N57-L60 PolarHBondContact O-N 3.19Å; L60-G62 PolarHBondContact O-N 3.27Å; L60-I66 HydrophobicContact CD1-CD1 3.67Å; L60-I66 HydrophobicContact CD1-CG1 3.89Å; L60-R133 HydrophobicContact CD2-CB 3.88Å; L60-L135 HydrophobicContact CD2-CD2 4.13Å; L60-F231 HydrophobicContact CD2-CE1 3.52Å; L60-F231 HydrophobicContact CD2-CZ 3.86Å
61A90.6Very high90.4Very high46 Ų4659.3 Ų59.338%0.3836%0.356SS..SBendtrans-80.9116.8166.100000109.7V134 D136A61-V134 HydrophobicContact CB-CG2 3.92Å; A61-V134 PolarHBondContact N-O 3.45Å; A61-D136 HydrophobicContact CB-CB 4.4Å
62G80.5Confident90.6Very high56 Ų5661.4 Ų61.458%0.57737%0.365SS*.SBendtrans93.8168.3170.900000116L60 R133L60-G62 PolarHBondContact O-N 3.27Å; G62-R133 PolarHBondContact O-NH2 3.42Å
63D77.9Confident90.7Very high147 Ų14763.7 Ų63.779%0.78638%0.376SS*.SBendtrans-99163.9-177.4-75.1-47.7000112.7R133D63-R133 PolarHBondContact O-NH1 2.96Å; D63-R133 VanDerWaalsContact O-NH1 3.15Å
64P84.4Confident90.8Very high90 Ų9062.1 Ų62.158%0.58437%0.367SS*.SBendcis-84.5165.5-8.834.5-35.5000112.6R133P64-R133 PolarHBondContact O-NH1 3.07Å; P64-R133 PolarHBondContact O-NH2 3.27Å
65P89.3Confident90.5Very high74 Ų7462.1 Ų62.148%0.48137%0.368SS..PPolyproline II helixtrans-65.4148.3176.327.2-35.3000112.2N57N57-P65 HydrophobicContact CB-CB 4.24Å
66I89.9Confident90.2Very high7 Ų763.3 Ų63.34%0.03637%0.372CS..PPolyproline II helixtrans-74.7123.9172.1-59.1179.8000108.3L32 L56 N57 L60 L126 E129L32-I66 HydrophobicContact CD1-CG2 4.28Å; L56-I66 HydrophobicContact CD2-CD1 4.23Å; N57-I66 PolarHBondContact ND2-O 3Å; N57-I66 WeakPolarHBondContact OD1-CB 3.48Å; N57-I66 PolarHBondContact OD1-N 3.05Å; L60-I66 HydrophobicContact CD1-CD1 3.67Å; L60-I66 HydrophobicContact CD1-CG1 3.89Å; I66-L126 HydrophobicContact CG2-CD1 3.58Å; I66-E129 HydrophobicContact CG2-CB 4.25Å
67T88.3Confident89.9Confident93 Ų9371.3 Ų71.357%0.57141%0.407SS*.  trans-106.8108.6177.847.80000109.5T69T67-T69 PolarHBondContact O-N 3.4Å
68P84.4Confident89.4Confident40 Ų4069.9 Ų69.926%0.2640%0.398SS..PPolyproline II helixtrans-67.2130.9-174.928.1-32.3000109.3L31 L32 V70 A121L31-P68 HydrophobicContact CB-CG 4.26Å; L32-P68 HydrophobicContact CD1-CB 4.01Å; L32-P68 HydrophobicContact CD1-CG 3.81Å; L32-P68 HydrophobicContact CD2-CB 4.41Å; L32-P68 HydrophobicContact CG-CB 4.09Å; L32-P68 HydrophobicContact CG-CG 3.99Å; P68-V70 PolarHBondContact O-N 3.4Å; P68-A121 HydrophobicContact CB-CB 4.47Å
69T90.5Very high88.7Confident52 Ų5269.6 Ų69.632%0.31940%0.403SS..PPolyproline II helixtrans-78.1119.7167.1-60.20000108.3T67 A121 D122 K125T67-T69 PolarHBondContact O-N 3.4Å; T69-A121 WeakPolarHBondContact O-CA 3.46Å; T69-D122 PolarHBondContact O-N 3.22Å; T69-K125 WeakPolarHBondContact OG1-CD 3.43Å; T69-K125 VanDerWaalsContact OG1-CE 3.28Å; T69-K125 WeakPolarHBondContact OG1-CE 3.49Å; T69-K125 PolarHBondContact OG1-NZ 3.41Å
70V92.1Very high87.8Confident69 Ų6970.2 Ų70.242%0.41841%0.407SS..EExtended strand (participates in β ladder)trans-102.1124.2-172.7-171.70000109.8L31 P68 H119L31-V70 HydrophobicContact CD1-CB 4.12Å; L31-V70 HydrophobicContact CD1-CG1 3.72Å; L31-V70 HydrophobicContact CD1-CG2 3.45Å; L31-V70 VanDerWaalsContact CD1-CG2 3.45Å; P68-V70 PolarHBondContact O-N 3.4Å; V70-H119 HydrophobicContact CG1-CB 3.9Å
71L92.2Very high86.7Confident89 Ų8974.2 Ų74.247%0.46643%0.432SS..EExtended strand (participates in β ladder)trans-88120.2165.5-60.2173.8000108I73 H119 E120L71-I73 HydrophobicContact CB-CD1 4.27Å; L71-I73 HydrophobicContact CB-CG1 4.28Å; L71-H119 WeakPolarHBondContact O-CA 3.47Å; L71-E120 PolarHBondContact N-O 2.92Å; L71-E120 PolarHBondContact O-N 2.96Å
72D93.7Very high85.1Confident85 Ų8576.6 Ų76.646%0.45543%0.432SS..EExtended strand (participates in β ladder)trans-98.6114.8173.2-17817.5000109.2K117 H119D72-K117 VanDerWaalsContact OD1-CD 3.31Å; D72-K117 WeakPolarHBondContact OD1-CD 3.47Å; D72-K117 IonicContact OD1-NZ 3.01Å; D72-K117 IonicContact OD2-NZ 3.37Å; D72-K117 PolarHBondContact OD2-NZ 2.99Å; D72-H119 IonicContact OD1-CD2 3.85Å; D72-H119 PolarHBondContact OD1-CD2 2.86Å; D72-H119 IonicContact OD1-NE2 3.74Å; D72-H119 PolarHBondContact OD1-NE2 3.16Å
73I93.8Very high83.8Confident70 Ų7076 Ų7636%0.35943%0.426SS..EExtended strand (participates in β ladder)trans-125.4128.4-169.7-53.1171.4000108.9L71 F75 K117 K118L71-I73 HydrophobicContact CB-CD1 4.27Å; L71-I73 HydrophobicContact CB-CG1 4.28Å; I73-F75 PolarHBondContact O-N 2.82Å; I73-K117 CarbonylContact O-C 3.57Å; I73-K117 WeakPolarHBondContact O-CA 3.46Å; I73-K118 HydrophobicContact CB-CB 4.35Å; I73-K118 PolarHBondContact N-O 3.02Å; I73-K118 PolarHBondContact O-N 2.86Å
74D93.1Very high82.1Confident129 Ų12971.3 Ų71.369%0.6941%0.412SS*.EExtended strand (participates in β ladder)trans-63.5125.9169.7-69.2-31000109.8K117D74-K117 WeakPolarHBondContact OD1-CE 3.41Å
75F89.1Confident80Confident73 Ų7368.2 Ų68.232%0.3240%0.397SS..EExtended strand (participates in β ladder)trans-101.7-90.8-173.3-170.6-122.3000111.8F9 V13 I73 L116 K118 I160F9-F75 HydrophobicContact CZ-CD1 4.49Å; F9-F75 HydrophobicContact CZ-CE1 4.01Å; V13-F75 HydrophobicContact CG2-CE1 4.5Å; I73-F75 PolarHBondContact O-N 2.82Å; F75-L116 HydrophobicContact CB-CB 4.44Å; F75-L116 WeakPolarHBondContact CB-O 3.28Å; F75-L116 HydrophobicContact CD1-CB 4.42Å; F75-L116 PolarHBondContact N-O 2.81Å; F75-K118 HydrophobicContact CB-CB 4.24Å; F75-K118 HydrophobicContact CD2-CB 4.42Å; F75-K118 HydrophobicContact CG-CB 4.47Å; F75-I160 HydrophobicContact CD1-CD1 4.06Å; F75-I160 HydrophobicContact CD1-CG2 4.05Å; F75-I160 HydrophobicContact CE1-CD1 4.18Å; F75-I160 HydrophobicContact CG-CD1 4.27Å; F75-I160 HydrophobicContact CZ-CD1 4.47Å
76I89.1Confident77.7Confident64 Ų6467.6 Ų67.633%0.32839%0.388SS..EExtended strand (participates in β ladder)trans-146.6168.2-179.669.9177.1000111.2F9 V13 L116F9-I76 HydrophobicContact CE2-CD1 3.97Å; F9-I76 HydrophobicContact CE2-CG1 4.46Å; V13-I76 HydrophobicContact CB-CD1 4.25Å; V13-I76 HydrophobicContact CG1-CD1 3.47Å; V13-I76 VanDerWaalsContact CG1-CD1 3.47Å; I76-L116 HydrophobicContact CG1-CD1 4.16Å; I76-L116 WeakPolarHBondContact O-CB 3.4Å; I76-L116 PolarHBondContact O-N 3.24Å
77K88.8Confident75.1Confident169 Ų16975.1 Ų75.174%0.73542%0.423SS*.EExtended strand (participates in β ladder)trans-103.8130.3164.2-176.7177.4179.9179.50109.6G114K77-G114 CarbonylContact C-O 3.51Å; K77-G114 VanDerWaalsContact CA-O 3.24Å; K77-G114 WeakPolarHBondContact CA-O 3.3Å
78Y85.4Confident72.3Confident12 Ų1273.7 Ų73.75%0.04743%0.427CS..EExtended strand (participates in β ladder)trans-124.5133.4-173.9-177.1-90000113.9F9 E12 V13 S80 F113 G114F9-Y78 HydrophobicContact CB-CE1 4.31Å; F9-Y78 HydrophobicContact CB-CE2 4.41Å; F9-Y78 HydrophobicContact CD2-CD1 4.04Å; F9-Y78 AromaticContact CD2-CD2 3.58Å; F9-Y78 HydrophobicContact CD2-CD2 3.58Å; F9-Y78 HydrophobicContact CD2-CE1 4.31Å; F9-Y78 AromaticContact CD2-CE2 3.86Å; F9-Y78 HydrophobicContact CD2-CE2 3.86Å; F9-Y78 AromaticContact CD2-CG 3.64Å; F9-Y78 HydrophobicContact CD2-CG 3.64Å; F9-Y78 HydrophobicContact CE2-CD2 4.12Å; F9-Y78 HydrophobicContact CE2-CG 4.13Å; E12-Y78 WeakPolarHBondContact OE2-CE2 3.35Å; V13-Y78 HydrophobicContact CG1-CD2 4.42Å; Y78-S80 WeakPolarHBondContact CE1-OG 3.45Å; Y78-S80 WeakPolarHBondContact OH-CB 3.5Å; Y78-S80 PolarHBondContact OH-OG 3.32Å; Y78-F113 HydrophobicContact CD1-CB 4.41Å; Y78-F113 AromaticContact CD1-CD2 3.45Å; Y78-F113 HydrophobicContact CD1-CD2 3.45Å; Y78-F113 VanDerWaalsContact CD1-CD2 3.45Å; Y78-F113 HydrophobicContact CD1-CE2 4.17Å; Y78-F113 HydrophobicContact CD1-CG 4.31Å; Y78-F113 AromaticContact CE1-CD2 3.84Å; Y78-F113 HydrophobicContact CE1-CD2 3.84Å; Y78-F113 HydrophobicContact CE1-CE2 4.09Å; Y78-F113 HydrophobicContact CG-CD2 4.31Å; Y78-F113 PolarHBondContact O-N 2.81Å; Y78-F113 VanDerWaalsContact O-N 3.09Å; Y78-G114 PolarHBondContact N-O 2.54Å; Y78-G114 PolarHBondContact O-N 2.89Å
79S80Confident69.7Low80 Ų8075.8 Ų75.856%0.55944%0.443SS*.EExtended strand (participates in β ladder)trans-153.6130.4170.1-173.70000109.9S111S79-S111 CarbonylContact C-O 3.57Å; S79-S111 WeakPolarHBondContact CA-O 3.19Å
80S74.8Confident66.8Low14 Ų1480.6 Ų80.610%0.09846%0.463CS..EExtended strand (participates in β ladder)trans-143.4153.6-176.965.90000111.6Y78 Q110 S111Y78-S80 WeakPolarHBondContact CE1-OG 3.45Å; Y78-S80 WeakPolarHBondContact OH-CB 3.5Å; Y78-S80 PolarHBondContact OH-OG 3.32Å; S80-Q110 CarbonylContact O-C 3.48Å; S80-Q110 WeakPolarHBondContact O-CA 3.4Å; S80-S111 PolarHBondContact N-O 3.43Å; S80-S111 PolarHBondContact O-N 2.84Å
81T72.3Confident64Low100 Ų10084.8 Ų84.861%0.61348%0.483SS*.EExtended strand (participates in β ladder)trans-124.5122.4169.7-55.50000109.3Q110T81-Q110 HydrophobicContact CG2-CB 4.45Å
82Y57.8Low60.9Low95 Ų9583.8 Ų83.837%0.37349%0.488SS..EExtended strand (participates in β ladder)trans-117.9129.5-178-161.4-92.9000109.5K108 L109Y82-K108 CarbonylContact O-C 3.52Å; Y82-K108 WeakPolarHBondContact O-CA 3.46Å; Y82-L109 PolarHBondContact N-O 2.67Å; Y82-L109 WeakPolarHBondContact O-CA 3.4Å; Y82-L109 PolarHBondContact O-N 2.74Å
83G53.5Low58Low44 Ų4484.8 Ų84.845%0.45450%0.502SS..EExtended strand (participates in β ladder)trans-123.3126.8-175.700000112.9
84G42.6Very low54.8Low48 Ų4890.6 Ų90.650%0.49552%0.524SS..  trans-92.18.3172.800000114.6S107G84-S107 WeakPolarHBondContact CA-O 3.39Å; G84-S107 PolarHBondContact N-O 2.84Å
85G38.5Very low51.7Low25 Ų2591.1 Ų91.126%0.25853%0.532SS..SBendtrans-79.6117.2164.700000109.7E87G85-E87 PolarHBondContact O-N 2.89Å
86M42Very low48.8Very low62 Ų6295 Ų9531%0.30555%0.549SS..SBendtrans-71.961.6168.3-160.2158.4162.500109.8L99 V101 V373M86-L99 HydrophobicContact CE-CB 3.94Å; M86-L99 HydrophobicContact CE-CD1 4.04Å; M86-V101 HydrophobicContact CE-CB 4.3Å; M86-V101 HydrophobicContact CE-CG2 3.74Å; M86-V101 HydrophobicContact SD-CB 3.98Å; M86-V101 HydrophobicContact SD-CG2 4.04Å; M86-V373 HydrophobicContact CE-CG2 4.35Å; M86-V373 HydrophobicContact SD-CG2 4.24Å
87E34.8Very low46Very low165 Ų16594.2 Ų94.277%0.77155%0.552SS**  trans-126.463.2160.3-158179.3-164.200106.9G85 S89G85-E87 PolarHBondContact O-N 2.89Å; E87-S89 PolarHBondContact O-N 2.85Å
88G30.2Very low43.2Very low62 Ų6294.9 Ų94.964%0.63956%0.555SS**  trans-89.995.117900000111.4M90G88-M90 PolarHBondContact O-N 2.83Å; G88-M90 VanDerWaalsContact O-N 3.13Å
89S29.6Very low40.7Very low85 Ų8595.7 Ų95.759%0.59456%0.56SS**  trans-72.488.6146.2170.30000107.1E87 D91E87-S89 PolarHBondContact O-N 2.85Å; S89-D91 PolarHBondContact O-N 2.79Å
90M30.3Very low38.3Very low153 Ų15398.3 Ų98.375%0.75457%0.568SS**  trans-68.1113.7167.7-75.9176.973.500108.9G88 A92G88-M90 PolarHBondContact O-N 2.83Å; G88-M90 VanDerWaalsContact O-N 3.13Å; M90-A92 PolarHBondContact O-N 2.88Å
91D33Very low36.4Very low157 Ų157100 Ų10084%0.8458%0.577SS**  trans-88.881.5168.7-136.98.8000108.2S89S89-D91 PolarHBondContact O-N 2.79Å
92A27Very low34.4Very low67 Ų67103.4 Ų103.455%0.55458%0.583SS**SBendtrans-163.576.9163.400000109M90 F94M90-A92 PolarHBondContact O-N 2.88Å; A92-F94 PolarHBondContact O-N 3.35Å
93S31.8Very low33.4Very low107 Ų107102.4 Ų102.475%0.74859%0.59SS**SBendtrans36.943.8153.970.20000119.7
94F27.8Very low32.8Very low191 Ų191106.1 Ų106.184%0.83860%0.596SS**SBendtrans-148.4141.4155.8-77.9-78.7000108.6A92A92-F94 PolarHBondContact O-N 3.35Å
95V28.1Very low32.9Very low140 Ų140107.2 Ų107.285%0.84859%0.59SS**  trans-25.1120.7-166-177.50000116.2A97V95-A97 PolarHBondContact O-N 3.1Å
96K27.3Very low33.6Very low154 Ų154107.4 Ų107.467%0.6759%0.588SS**  trans-67.489.1170.8-80.7177.5173.4173.40110.6
97A30.5Very low34.2Very low48 Ų48106.7 Ų106.740%0.39759%0.589SS.*  trans-85.8123.5161.100000108.9V95 L99V95-A97 PolarHBondContact O-N 3.1Å; A97-L99 PolarHBondContact O-N 3.43Å
98K28.9Very low35.9Very low183 Ų183103.7 Ų103.780%0.79657%0.574SS**  trans-96.474.1-175.8-140.4-174.2-171-171.50108.3N100K98-N100 PolarHBondContact O-N 3.35Å
99L32.9Very low37.8Very low30 Ų30101.3 Ų101.316%0.15755%0.546CS..  trans-75.7103.2176.9-91.9173.7000110.5M86 A97 V101 E412 R413M86-L99 HydrophobicContact CE-CB 3.94Å; M86-L99 HydrophobicContact CE-CD1 4.04Å; A97-L99 PolarHBondContact O-N 3.43Å; L99-V101 VanDerWaalsContact C-N 3.26Å; L99-V101 PolarHBondContact O-N 3.39Å; L99-E412 HydrophobicContact CD1-CB 3.61Å; L99-E412 HydrophobicContact CD2-CB 3.93Å; L99-E412 WeakPolarHBondContact CD2-OE2 3.18Å; L99-E412 HydrophobicContact CG-CB 3.85Å; L99-E412 WeakPolarHBondContact CG-OE2 3.36Å; L99-R413 HydrophobicContact CD1-CG 4.44Å
100N29.8Very low40.1Very low135 Ų135101 Ų10172%0.72254%0.535SS*.  trans-78.675.5166.3-88.2-9.7000109.5K98 K102K98-N100 PolarHBondContact O-N 3.35Å; N100-K102 PolarHBondContact O-N 2.69Å
101V35.8Very low42.4Very low49 Ų4993.7 Ų93.730%0.29750%0.499SS..  trans-75.3108.5156.4178.30000105.6M86 L99 S103M86-V101 HydrophobicContact CE-CB 4.3Å; M86-V101 HydrophobicContact CE-CG2 3.74Å; M86-V101 HydrophobicContact SD-CB 3.98Å; M86-V101 HydrophobicContact SD-CG2 4.04Å; L99-V101 VanDerWaalsContact C-N 3.26Å; L99-V101 PolarHBondContact O-N 3.39Å; V101-S103 PolarHBondContact O-N 2.79Å
102K30.6Very low44.9Very low171 Ų17188 Ų8874%0.74347%0.472SS*.  trans-7276.5-178.3-156.5-175.1-175.2-162.90109.2N100 E104N100-K102 PolarHBondContact O-N 2.69Å; K102-E104 PolarHBondContact O-N 2.83Å
103S36.3Very low47.7Very low74 Ų7484.9 Ų84.952%0.51745%0.446SS..  trans-73.5113.1159.3-172.90000106.4V101 D105V101-S103 PolarHBondContact O-N 2.79Å; S103-D105 PolarHBondContact O-N 3.37Å; S103-D105 VanDerWaalsContact O-N 3.17Å; S103-D105 PolarHBondContact OG-O 2.69Å
104E41.6Very low50.4Low122 Ų12280.6 Ų80.657%0.5742%0.419SS*.SBendtrans-66.1-11.6179.5-75.3-174.6150.600112.9K102 Q175K102-E104 PolarHBondContact O-N 2.83Å; E104-Q175 PolarHBondContact O-N 2.74Å
105D44.1Very low53.3Low71 Ų7174.2 Ų74.238%0.3840%0.397SS..EExtended strand (participates in β ladder)trans-122.9125.4179-65.9-6.9000109.7S103 Q174S103-D105 PolarHBondContact O-N 3.37Å; S103-D105 VanDerWaalsContact O-N 3.17Å; S103-D105 PolarHBondContact OG-O 2.69Å; D105-Q174 WeakPolarHBondContact OD1-CG 3.2Å; D105-Q174 PolarHBondContact OD2-NE2 2.78Å
106S52.8Low56.5Low30 Ų3067.7 Ų67.721%0.2136%0.358CS..EExtended strand (participates in β ladder)trans-116.2119.7168.169.50000109.5Q173S106-Q173 PolarHBondContact N-O 3.28Å; S106-Q173 VanDerWaalsContact N-O 3.13Å; S106-Q173 PolarHBondContact O-N 3.21Å
107S56Low59.7Low47 Ų4763.2 Ų63.233%0.32934%0.338SS..EExtended strand (participates in β ladder)trans-103.4138.5172.659.60000110.7G84 D171G84-S107 WeakPolarHBondContact CA-O 3.39Å; G84-S107 PolarHBondContact N-O 2.84Å; S107-D171 CarbonylContact C-O 3.49Å; S107-D171 VanDerWaalsContact CA-O 3.26Å; S107-D171 WeakPolarHBondContact CA-O 3.32Å
108K69.5Low62.8Low102 Ų10262.7 Ų62.744%0.44333%0.327SS..EExtended strand (participates in β ladder)trans-122121171.3-66.6178.1-178.8172.70109.4Y82 E170 D171Y82-K108 CarbonylContact O-C 3.52Å; Y82-K108 WeakPolarHBondContact O-CA 3.46Å; K108-E170 CarbonylContact O-C 3.59Å; K108-E170 WeakPolarHBondContact O-CA 3.14Å; K108-D171 HydrophobicContact CB-CB 4.31Å; K108-D171 PolarHBondContact N-O 3.5Å; K108-D171 PolarHBondContact O-N 3.09Å
109L70.1Confident66Low12 Ų1255.5 Ų55.56%0.06330%0.296CS..EExtended strand (participates in β ladder)trans-98.9106.1176.3-169.773.4000111M1 I4 Y82 V168 I169 E170M1-L109 HydrophobicContact CB-CD1 4.33Å; M1-L109 HydrophobicContact CG-CD1 4.06Å; I4-L109 HydrophobicContact CB-CD2 3.79Å; I4-L109 HydrophobicContact CG2-CD2 3.48Å; I4-L109 VanDerWaalsContact CG2-CD2 3.48Å; Y82-L109 PolarHBondContact N-O 2.67Å; Y82-L109 WeakPolarHBondContact O-CA 3.4Å; Y82-L109 PolarHBondContact O-N 2.74Å; L109-V168 HydrophobicContact CD1-CG1 3.51Å; L109-V168 HydrophobicContact CG-CG1 4.07Å; L109-I169 CarbonylContact C-O 3.49Å; L109-I169 WeakPolarHBondContact CA-O 3.34Å; L109-E170 HydrophobicContact CD1-CB 3.91Å; L109-E170 HydrophobicContact CD1-CG 4.35Å
110Q77.3Confident69Low77 Ų7756.4 Ų56.436%0.3630%0.3SS..EExtended strand (participates in β ladder)trans-90.9125.5167.7-175.9176.5-16.400109.9S80 T81 V168 I169S80-Q110 CarbonylContact O-C 3.48Å; S80-Q110 WeakPolarHBondContact O-CA 3.4Å; T81-Q110 HydrophobicContact CG2-CB 4.45Å; Q110-V168 CarbonylContact O-C 3.45Å; Q110-V168 WeakPolarHBondContact O-CA 3.47Å; Q110-I169 HydrophobicContact CB-CB 4.4Å; Q110-I169 PolarHBondContact N-O 3.21Å; Q110-I169 PolarHBondContact O-N 3.38Å
111S79.1Confident72.1Confident0 Ų050 Ų500%027%0.266CS..EExtended strand (participates in β ladder)trans-122122.6-178.5-56.50000109.9A5 S79 S80A5-S111 VanDerWaalsContact CB-OG 3.23Å; A5-S111 WeakPolarHBondContact CB-OG 3.49Å; S79-S111 CarbonylContact C-O 3.57Å; S79-S111 WeakPolarHBondContact CA-O 3.19Å; S80-S111 PolarHBondContact N-O 3.43Å; S80-S111 PolarHBondContact O-N 2.84Å
112S85.4Confident74.8Confident39 Ų3950.1 Ų50.127%0.27327%0.265SS..EExtended strand (participates in β ladder)trans-130.1107.9174.4169.70000109.2C166 S167S112-C166 VanDerWaalsContact O-CB 3.26Å; S112-C166 WeakPolarHBondContact O-CB 3.48Å; S112-S167 PolarHBondContact N-O 3.09Å; S112-S167 PolarHBondContact O-N 2.94Å; S112-S167 VanDerWaalsContact O-O 3.12Å
113F87.1Confident77.8Confident1 Ų143.2 Ų43.20%0.00424%0.237CC..EExtended strand (participates in β ladder)trans-92.3-5.5176.9-62.5-59.7000113.3A5 T6 F9 Y78 L116 V168 I210 I216A5-F113 HydrophobicContact CB-CE1 4.43Å; A5-F113 HydrophobicContact CB-CE2 4.25Å; A5-F113 HydrophobicContact CB-CZ 3.58Å; T6-F113 HydrophobicContact CG2-CZ 4.13Å; F9-F113 HydrophobicContact CB-CD2 4.26Å; F9-F113 HydrophobicContact CB-CE2 3.8Å; F9-F113 HydrophobicContact CD2-CD2 4.2Å; F9-F113 HydrophobicContact CG-CD2 4.34Å; F9-F113 HydrophobicContact CG-CE2 4.29Å; Y78-F113 HydrophobicContact CD1-CB 4.41Å; Y78-F113 AromaticContact CD1-CD2 3.45Å; Y78-F113 HydrophobicContact CD1-CD2 3.45Å; Y78-F113 VanDerWaalsContact CD1-CD2 3.45Å; Y78-F113 HydrophobicContact CD1-CE2 4.17Å; Y78-F113 HydrophobicContact CD1-CG 4.31Å; Y78-F113 AromaticContact CE1-CD2 3.84Å; Y78-F113 HydrophobicContact CE1-CD2 3.84Å; Y78-F113 HydrophobicContact CE1-CE2 4.09Å; Y78-F113 HydrophobicContact CG-CD2 4.31Å; Y78-F113 PolarHBondContact O-N 2.81Å; Y78-F113 VanDerWaalsContact O-N 3.09Å; F113-L116 HydrophobicContact CB-CD1 4.39Å; F113-L116 HydrophobicContact CB-CD2 3.94Å; F113-L116 HydrophobicContact CB-CG 4.46Å; F113-V168 HydrophobicContact CE1-CG2 4.16Å; F113-V168 HydrophobicContact CZ-CG2 4.47Å; F113-I210 HydrophobicContact CD1-CD1 4.01Å; F113-I210 HydrophobicContact CE1-CD1 3.62Å; F113-I216 HydrophobicContact CB-CD1 4.4Å; F113-I216 HydrophobicContact CD1-CG2 4.12Å; F113-I216 HydrophobicContact CD2-CD1 4.06Å; F113-I216 HydrophobicContact CE1-CG2 4.11Å; F113-I216 HydrophobicContact CG-CD1 4.14Å
114G87.1Confident80.5Confident17 Ų1743.9 Ų43.918%0.17524%0.24CC..EExtended strand (participates in β ladder)trans65.7-150.4-179.500000111.7K77 Y78K77-G114 CarbonylContact C-O 3.51Å; K77-G114 VanDerWaalsContact CA-O 3.24Å; K77-G114 WeakPolarHBondContact CA-O 3.3Å; Y78-G114 PolarHBondContact N-O 2.54Å; Y78-G114 PolarHBondContact O-N 2.89Å
115S89.5Confident82.9Confident56 Ų5641 Ų4139%0.39223%0.225SC..EExtended strand (participates in β ladder)trans-77.5133.9177.8-61.10000110.8T163S115-T163 WeakPolarHBondContact O-CB 3.45Å; S115-T163 WeakPolarHBondContact O-CG2 3.39Å; S115-T163 PolarHBondContact O-N 2.91Å; S115-T163 PolarHBondContact O-OG1 3.23Å
116L94.3Very high85.3Confident4 Ų437.9 Ų37.92%0.02121%0.208CC..EExtended strand (participates in β ladder)trans-118.2148-174-61.2172.3000110.9F9 F75 I76 F113 I160 V161 T162 I216F9-L116 HydrophobicContact CD2-CD1 4.28Å; F9-L116 HydrophobicContact CE2-CD1 3.31Å; F9-L116 HydrophobicContact CZ-CD1 3.54Å; F75-L116 HydrophobicContact CB-CB 4.44Å; F75-L116 WeakPolarHBondContact CB-O 3.28Å; F75-L116 HydrophobicContact CD1-CB 4.42Å; F75-L116 PolarHBondContact N-O 2.81Å; I76-L116 HydrophobicContact CG1-CD1 4.16Å; I76-L116 WeakPolarHBondContact O-CB 3.4Å; I76-L116 PolarHBondContact O-N 3.24Å; F113-L116 HydrophobicContact CB-CD1 4.39Å; F113-L116 HydrophobicContact CB-CD2 3.94Å; F113-L116 HydrophobicContact CB-CG 4.46Å; L116-I160 HydrophobicContact CB-CG2 4Å; L116-I160 HydrophobicContact CD1-CG2 4.1Å; L116-I160 HydrophobicContact CG-CG2 4.44Å; L116-V161 WeakPolarHBondContact CA-O 3.4Å; L116-T162 HydrophobicContact CD2-CG2 4.12Å; L116-I216 HydrophobicContact CD1-CD1 3.61Å; L116-I216 HydrophobicContact CD2-CD1 3.7Å; L116-I216 HydrophobicContact CG-CD1 4.29Å
117K95.7Very high87.1Confident59 Ų5940 Ų4026%0.25722%0.216SC..EExtended strand (participates in β ladder)trans-117.6147.6172.4-80.9177.7157.3-153.10110.7D72 I73 D74 I160 V161 T163D72-K117 VanDerWaalsContact OD1-CD 3.31Å; D72-K117 WeakPolarHBondContact OD1-CD 3.47Å; D72-K117 IonicContact OD1-NZ 3.01Å; D72-K117 IonicContact OD2-NZ 3.37Å; D72-K117 PolarHBondContact OD2-NZ 2.99Å; I73-K117 CarbonylContact O-C 3.57Å; I73-K117 WeakPolarHBondContact O-CA 3.46Å; D74-K117 WeakPolarHBondContact OD1-CE 3.41Å; K117-I160 CarbonylContact O-C 3.48Å; K117-I160 WeakPolarHBondContact O-CA 3.32Å; K117-V161 HydrophobicContact CB-CG2 3.96Å; K117-V161 PolarHBondContact N-O 2.84Å; K117-V161 PolarHBondContact O-N 2.86Å; K117-T163 HydrophobicContact CB-CG2 4.14Å; K117-T163 HydrophobicContact CD-CG2 3.73Å; K117-T163 HydrophobicContact CG-CG2 3.63Å
118K95.7Very high88.9Confident38 Ų3846.5 Ų46.517%0.16523%0.233CC..EExtended strand (participates in β ladder)trans-103.9118.8171.3-178.5-178.1-171.3-157.90108.3I73 F75 E120 E158 R159 I160I73-K118 HydrophobicContact CB-CB 4.35Å; I73-K118 PolarHBondContact N-O 3.02Å; I73-K118 PolarHBondContact O-N 2.86Å; F75-K118 HydrophobicContact CB-CB 4.24Å; F75-K118 HydrophobicContact CD2-CB 4.42Å; F75-K118 HydrophobicContact CG-CB 4.47Å; K118-E120 WeakPolarHBondContact CE-OE2 3.44Å; K118-E120 IonicContact NZ-OE1 3.47Å; K118-E120 IonicContact NZ-OE2 3.09Å; K118-E120 PolarHBondContact NZ-OE2 2.81Å; K118-E158 WeakPolarHBondContact CE-OE2 3.4Å; K118-E158 IonicContact NZ-OE2 3.02Å; K118-E158 PolarHBondContact NZ-OE2 2.86Å; K118-R159 WeakPolarHBondContact CA-O 3.03Å; K118-I160 HydrophobicContact CB-CD1 3.74Å; K118-I160 HydrophobicContact CD-CD1 4.27Å; K118-I160 HydrophobicContact CG-CD1 3.73Å
119H96.1Very high89.9Confident32 Ų3244.7 Ų44.715%0.14823%0.226CC..EExtended strand (participates in β ladder)trans-96.7121.7167.3-63.2162.8000108.6V70 L71 D72 E158 R159V70-H119 HydrophobicContact CG1-CB 3.9Å; L71-H119 WeakPolarHBondContact O-CA 3.47Å; D72-H119 IonicContact OD1-CD2 3.85Å; D72-H119 PolarHBondContact OD1-CD2 2.86Å; D72-H119 IonicContact OD1-NE2 3.74Å; D72-H119 PolarHBondContact OD1-NE2 3.16Å; H119-E158 CarbonylContact O-C 3.58Å; H119-E158 WeakPolarHBondContact O-CA 3.41Å; H119-R159 HydrophobicContact CB-CG 3.81Å; H119-R159 PolarHBondContact N-O 3.43Å; H119-R159 PolarHBondContact O-N 3.15Å
120E95.1Very high90.9Very high48 Ų4844.4 Ų44.422%0.22423%0.225CC..EExtended strand (participates in β ladder)trans-127.6132.7-178.2-176.9165.6-17200110.8L71 K118 E158L71-E120 PolarHBondContact N-O 2.92Å; L71-E120 PolarHBondContact O-N 2.96Å; K118-E120 WeakPolarHBondContact CE-OE2 3.44Å; K118-E120 IonicContact NZ-OE1 3.47Å; K118-E120 IonicContact NZ-OE2 3.09Å; K118-E120 PolarHBondContact NZ-OE2 2.81Å; E120-E158 HydrophobicContact CB-CB 4.26Å; E120-E158 HydrophobicContact CG-CB 4.19Å
121A94.2Very high91.5Very high2 Ų249.3 Ų49.32%0.01725%0.245CC..EExtended strand (participates in β ladder)trans-75138.6173.800000110.5L31 P68 T69 V123 K157L31-A121 HydrophobicContact CD1-CB 4.37Å; L31-A121 HydrophobicContact CD2-CB 4.38Å; P68-A121 HydrophobicContact CB-CB 4.47Å; T69-A121 WeakPolarHBondContact O-CA 3.46Å; A121-V123 VanDerWaalsContact C-N 3.32Å; A121-V123 PolarHBondContact O-N 3.33Å; A121-K157 WeakPolarHBondContact CB-O 3.34Å; A121-K157 PolarHBondContact N-O 2.95Å
122D94.1Very high92Very high50 Ų5052.9 Ų52.927%0.26728%0.283SS..  trans-66.390.3168.2-177.9-20.6000109.7T69 P124 K125 L126T69-D122 PolarHBondContact O-N 3.22Å; D122-P124 WeakPolarHBondContact OD1-CD 3.21Å; D122-K125 HydrophobicContact CB-CB 3.96Å; D122-K125 VanDerWaalsContact CG-CB 3.4Å; D122-K125 PolarHBondContact O-N 3.09Å; D122-K125 WeakPolarHBondContact OD1-CB 3.42Å; D122-K125 PolarHBondContact OD1-N 3.48Å; D122-L126 WeakPolarHBondContact O-CB 3.26Å; D122-L126 PolarHBondContact O-N 2.91Å
123V92.4Very high92.4Very high27 Ų2753.3 Ų53.316%0.16428%0.278CS..Hα-helixtrans-58.2-45-178.3177.70000112.1A121 K125 L126 M127 I221A121-V123 VanDerWaalsContact C-N 3.32Å; A121-V123 PolarHBondContact O-N 3.33Å; V123-K125 VanDerWaalsContact C-N 3.33Å; V123-K125 PolarHBondContact O-N 3.49Å; V123-L126 PolarHBondContact O-N 2.81Å; V123-M127 HydrophobicContact CG1-CG 4.34Å; V123-M127 WeakPolarHBondContact O-CB 3.31Å; V123-M127 VanDerWaalsContact O-CG 3.31Å; V123-M127 WeakPolarHBondContact O-CG 3.33Å; V123-M127 PolarHBondContact O-N 3Å; V123-I221 HydrophobicContact CG1-CD1 4.12Å
124P93.1Very high92.8Very high88 Ų8855.6 Ų55.657%0.57129%0.292SS*.Hα-helixtrans-56.3-40.3173.4-28.134.6000114.6D122 R128D122-P124 WeakPolarHBondContact OD1-CD 3.21Å; P124-R128 PolarHBondContact O-N 3.19Å
125K93.2Very high93.2Very high62 Ų6255 Ų5527%0.2729%0.285SS..Hα-helixtrans-69.1-45.4174.6-176.4173.9168179.30111.4T69 D122 V123 M127 R128 E129T69-K125 WeakPolarHBondContact OG1-CD 3.43Å; T69-K125 VanDerWaalsContact OG1-CE 3.28Å; T69-K125 WeakPolarHBondContact OG1-CE 3.49Å; T69-K125 PolarHBondContact OG1-NZ 3.41Å; D122-K125 HydrophobicContact CB-CB 3.96Å; D122-K125 VanDerWaalsContact CG-CB 3.4Å; D122-K125 PolarHBondContact O-N 3.09Å; D122-K125 WeakPolarHBondContact OD1-CB 3.42Å; D122-K125 PolarHBondContact OD1-N 3.48Å; V123-K125 VanDerWaalsContact C-N 3.33Å; V123-K125 PolarHBondContact O-N 3.49Å; K125-M127 VanDerWaalsContact C-N 3.28Å; K125-M127 PolarHBondContact O-N 3.29Å; K125-R128 WeakPolarHBondContact O-CB 3.28Å; K125-R128 PolarHBondContact O-N 3.43Å; K125-E129 WeakPolarHBondContact CE-OE1 3.45Å; K125-E129 HydrophobicContact CG-CG 4.49Å; K125-E129 IonicContact NZ-OE1 2.73Å; K125-E129 PolarHBondContact O-N 3.47Å
126L92.9Very high93.4Very high4 Ų455.2 Ų55.22%0.02128%0.282CS..Hα-helixtrans-57-41177.6-177.861.6000112.1L32 I66 D122 V123 R128 E129 S130 I155 L233L32-L126 HydrophobicContact CD2-CD1 3.8Å; L32-L126 HydrophobicContact CD2-CD2 3.74Å; L32-L126 HydrophobicContact CD2-CG 4.44Å; I66-L126 HydrophobicContact CG2-CD1 3.58Å; D122-L126 WeakPolarHBondContact O-CB 3.26Å; D122-L126 PolarHBondContact O-N 2.91Å; V123-L126 PolarHBondContact O-N 2.81Å; L126-R128 VanDerWaalsContact C-N 3.35Å; L126-R128 PolarHBondContact O-N 3.05Å; L126-E129 PolarHBondContact O-N 3.21Å; L126-S130 VanDerWaalsContact O-CB 3.3Å; L126-S130 WeakPolarHBondContact O-CB 3.46Å; L126-S130 PolarHBondContact O-N 2.98Å; L126-S130 PolarHBondContact O-OG 3.26Å; L126-I155 HydrophobicContact CD2-CD1 3.98Å; L126-L233 HydrophobicContact CB-CD1 4.43Å; L126-L233 HydrophobicContact CD2-CD1 3.83Å; L126-L233 HydrophobicContact CG-CD1 3.74Å
127M92.4Very high93.4Very high75 Ų7557.1 Ų57.137%0.36929%0.291SS..Hα-helixtrans-59.9-41.7174.1-78.1-70.3-83.300112.8V123 K125 K131 L233V123-M127 HydrophobicContact CG1-CG 4.34Å; V123-M127 WeakPolarHBondContact O-CB 3.31Å; V123-M127 VanDerWaalsContact O-CG 3.31Å; V123-M127 WeakPolarHBondContact O-CG 3.33Å; V123-M127 PolarHBondContact O-N 3Å; K125-M127 VanDerWaalsContact C-N 3.28Å; K125-M127 PolarHBondContact O-N 3.29Å; M127-K131 PolarHBondContact O-N 3.38Å; M127-L233 HydrophobicContact CG-CD1 3.99Å; M127-L233 HydrophobicContact SD-CB 3.46Å; M127-L233 WeakPolarHBondContact SD-CB 3.08Å; M127-L233 HydrophobicContact SD-CD1 3.59Å; M127-L233 VanDerWaalsContact SD-CD1 3.59Å; M127-L233 HydrophobicContact SD-CG 3.71Å
128R92.1Very high93.3Very high183 Ų18358 Ų5869%0.69131%0.305SS*.Hα-helixtrans-68-40.5178-72.5-175.4-68.8174.2-0.4111.7P124 K125 L126 K131P124-R128 PolarHBondContact O-N 3.19Å; K125-R128 WeakPolarHBondContact O-CB 3.28Å; K125-R128 PolarHBondContact O-N 3.43Å; L126-R128 VanDerWaalsContact C-N 3.35Å; L126-R128 PolarHBondContact O-N 3.05Å; R128-K131 WeakPolarHBondContact O-CB 3.49Å; R128-K131 PolarHBondContact O-N 3.4Å
129E91Very high93.3Very high65 Ų6557.7 Ų57.730%0.30430%0.304SS..Hα-helixtrans-73.9-29.6-179.8-69.3176.4173.100112.8I66 K125 L126 K131 R133I66-E129 HydrophobicContact CG2-CB 4.25Å; K125-E129 WeakPolarHBondContact CE-OE1 3.45Å; K125-E129 HydrophobicContact CG-CG 4.49Å; K125-E129 IonicContact NZ-OE1 2.73Å; K125-E129 PolarHBondContact O-N 3.47Å; L126-E129 PolarHBondContact O-N 3.21Å; E129-K131 VanDerWaalsContact C-N 3.31Å; E129-R133 WeakPolarHBondContact O-CG 3.24Å
130S91.3Very high93.1Very high6 Ų659.2 Ų59.24%0.04232%0.318CS..Hα-helixtrans-77.9-16.5176.2-55.10000112.9L126 G132 R133L126-S130 VanDerWaalsContact O-CB 3.3Å; L126-S130 WeakPolarHBondContact O-CB 3.46Å; L126-S130 PolarHBondContact O-N 2.98Å; L126-S130 PolarHBondContact O-OG 3.26Å; S130-G132 PolarHBondContact O-N 3.46Å; S130-R133 WeakPolarHBondContact O-CB 3.43Å; S130-R133 WeakPolarHBondContact O-CG 3.48Å; S130-R133 PolarHBondContact O-N 3.18Å; S130-R133 VanDerWaalsContact O-N 3.07Å
131K90.6Very high93Very high179 Ų17958 Ų5878%0.77831%0.313SS*.THydrogen-bonded Turntrans-63.2122.1-173.2-170.9178.3-178.1179.40111.5M127 R128 E129 R133M127-K131 PolarHBondContact O-N 3.38Å; R128-K131 WeakPolarHBondContact O-CB 3.49Å; R128-K131 PolarHBondContact O-N 3.4Å; E129-K131 VanDerWaalsContact C-N 3.31Å; K131-R133 PolarHBondContact O-N 2.94Å
132G88.6Confident92.9Very high76 Ų7658 Ų5878%0.78431%0.312SS*.THydrogen-bonded Turntrans77.52179.500000114.3S130S130-G132 PolarHBondContact O-N 3.46Å
133R93.3Very high92.8Very high47 Ų4760.2 Ų60.218%0.17732%0.321CS..  trans-74.5150.2167.6-56.6-67.3-71.7-150.6-7.4108.9L60 G62 D63 P64 E129 S130 K131 F231L60-R133 HydrophobicContact CD2-CB 3.88Å; G62-R133 PolarHBondContact O-NH2 3.42Å; D63-R133 PolarHBondContact O-NH1 2.96Å; D63-R133 VanDerWaalsContact O-NH1 3.15Å; P64-R133 PolarHBondContact O-NH1 3.07Å; P64-R133 PolarHBondContact O-NH2 3.27Å; E129-R133 WeakPolarHBondContact O-CG 3.24Å; S130-R133 WeakPolarHBondContact O-CB 3.43Å; S130-R133 WeakPolarHBondContact O-CG 3.48Å; S130-R133 PolarHBondContact O-N 3.18Å; S130-R133 VanDerWaalsContact O-N 3.07Å; K131-R133 PolarHBondContact O-N 2.94Å; R133-F231 HydrophobicContact CB-CE1 3.99Å; R133-F231 HydrophobicContact CB-CZ 4.4Å
134V95.4Very high92.5Very high50 Ų5064.1 Ų64.130%0.30334%0.338SS..BIsolated β-bridgetrans-126.7148.6177.4-58.20000109.6A61 G229 Q230A61-V134 HydrophobicContact CB-CG2 3.92Å; A61-V134 PolarHBondContact N-O 3.45Å; V134-G229 CarbonylContact C-O 3.57Å; V134-G229 VanDerWaalsContact CA-O 3.31Å; V134-G229 WeakPolarHBondContact CA-O 3.39Å; V134-Q230 HydrophobicContact CG1-CG 3.98Å
135L95.8Very high92.2Very high5 Ų560.2 Ų60.23%0.02631%0.312CS..BIsolated β-bridgetrans-79146.6173.2-60.9173.1000110.2L56 L59 L60 M137 I142 I225 G229 F231L56-L135 HydrophobicContact CD1-CD2 4.04Å; L59-L135 HydrophobicContact CB-CD2 3.93Å; L59-L135 CarbonylContact O-C 3.55Å; L59-L135 VanDerWaalsContact O-CA 3.23Å; L59-L135 WeakPolarHBondContact O-CA 3.45Å; L60-L135 HydrophobicContact CD2-CD2 4.13Å; L135-M137 HydrophobicContact CB-SD 4.26Å; L135-M137 PolarHBondContact O-N 3.02Å; L135-I142 HydrophobicContact CB-CD1 3.81Å; L135-I142 HydrophobicContact CD1-CD1 4.31Å; L135-I142 HydrophobicContact CG-CD1 4.5Å; L135-I225 HydrophobicContact CD1-CB 4.5Å; L135-I225 HydrophobicContact CD1-CD1 3.57Å; L135-I225 HydrophobicContact CD1-CG1 3.76Å; L135-I225 HydrophobicContact CD1-CG2 3.91Å; L135-G229 PolarHBondContact N-O 2.76Å; L135-F231 HydrophobicContact CD1-CB 4.26Å; L135-F231 HydrophobicContact CD1-CD1 4.35Å; L135-F231 HydrophobicContact CD1-CG 4.4Å; L135-F231 HydrophobicContact CD2-CD1 4.08Å; L135-F231 HydrophobicContact CD2-CE1 4.17Å; L135-F231 HydrophobicContact CG-CD1 3.76Å; L135-F231 HydrophobicContact CG-CE1 4.3Å; L135-F231 HydrophobicContact CG-CG 4.28Å
136D95.2Very high91.9Very high59 Ų5961 Ų6132%0.31632%0.316SS..  trans-71.393.7167.5178.59.4000109.5L59 A61 S138 H139 I142L59-D136 PolarHBondContact O-N 3.34Å; A61-D136 HydrophobicContact CB-CB 4.4Å; D136-S138 VanDerWaalsContact CG-OG 3.29Å; D136-S138 PolarHBondContact O-N 3.11Å; D136-S138 WeakPolarHBondContact OD1-CA 3.44Å; D136-S138 VanDerWaalsContact OD1-CB 3.3Å; D136-S138 WeakPolarHBondContact OD1-CB 3.23Å; D136-S138 PolarHBondContact OD1-N 3.38Å; D136-S138 PolarHBondContact OD1-OG 3.25Å; D136-S138 PolarHBondContact OD2-OG 3.41Å; D136-H139 HydrophobicContact CB-CB 4.47Å; D136-H139 WeakPolarHBondContact O-CB 3.45Å; D136-H139 PolarHBondContact O-N 3.18Å; D136-I142 VanDerWaalsContact O-CD1 3.31Å; D136-I142 WeakPolarHBondContact O-CD1 3.46Å
137M93.9Very high91.3Very high45 Ų4568.2 Ų68.222%0.22235%0.349CS..THydrogen-bonded Turntrans-64.4-9179.6-61.1-55.6-70.900113.6L135 I142 K146 I225 G229L135-M137 HydrophobicContact CB-SD 4.26Å; L135-M137 PolarHBondContact O-N 3.02Å; M137-I142 HydrophobicContact CE-CG2 3.89Å; M137-I142 HydrophobicContact SD-CG2 3.93Å; M137-K146 HydrophobicContact CE-CD 4.48Å; M137-I225 HydrophobicContact CE-CG2 4.41Å; M137-I225 HydrophobicContact SD-CG2 4.28Å; M137-G229 WeakPolarHBondContact SD-CA 3.27Å
138S93.4Very high90.6Very high78 Ų7867.7 Ų67.755%0.54535%0.345SS..THydrogen-bonded Turntrans-85-11.2171.980.10000113.5D136 S140 Q143D136-S138 VanDerWaalsContact CG-OG 3.29Å; D136-S138 PolarHBondContact O-N 3.11Å; D136-S138 WeakPolarHBondContact OD1-CA 3.44Å; D136-S138 VanDerWaalsContact OD1-CB 3.3Å; D136-S138 WeakPolarHBondContact OD1-CB 3.23Å; D136-S138 PolarHBondContact OD1-N 3.38Å; D136-S138 PolarHBondContact OD1-OG 3.25Å; D136-S138 PolarHBondContact OD2-OG 3.41Å; S138-S140 PolarHBondContact O-N 3.22Å; S138-Q143 PolarHBondContact O-NE2 3.07Å
139H95Very high89.5Confident31 Ų3167.3 Ų67.314%0.14435%0.351CS..SBendtrans-62.4131.8179.5-168.7-78.2000111.3F54 L59 D136 L141 I142 Q143F54-H139 AromaticContact CD1-CE1 3.87Å; F54-H139 AromaticContact CD1-NE2 3.73Å; F54-H139 AromaticContact CE1-CE1 3.65Å; F54-H139 AromaticContact CE1-NE2 3.5Å; F54-H139 WeakPolarHBondContact CE1-NE2 3.35Å; F54-H139 AromaticContact CZ-CE1 3.83Å; L59-H139 HydrophobicContact CD2-CB 4.45Å; L59-H139 VanDerWaalsContact CD2-CE1 3.48Å; L59-H139 WeakPolarHBondContact CD2-CE1 3.26Å; L59-H139 WeakPolarHBondContact CD2-ND1 3.27Å; D136-H139 HydrophobicContact CB-CB 4.47Å; D136-H139 WeakPolarHBondContact O-CB 3.45Å; D136-H139 PolarHBondContact O-N 3.18Å; H139-L141 VanDerWaalsContact C-N 3.32Å; H139-L141 VanDerWaalsContact ND1-CB 3.35Å; H139-L141 WeakPolarHBondContact ND1-CB 3.2Å; H139-L141 PolarHBondContact ND1-N 3.29Å; H139-L141 VanDerWaalsContact ND1-N 3.16Å; H139-L141 PolarHBondContact O-N 2.95Å; H139-I142 HydrophobicContact CB-CB 4.5Å; H139-I142 HydrophobicContact CB-CD1 4.16Å; H139-I142 HydrophobicContact CB-CG1 4.37Å; H139-I142 WeakPolarHBondContact O-CB 3.42Å; H139-I142 PolarHBondContact O-N 2.68Å; H139-Q143 PolarHBondContact O-N 2.72Å; H139-Q143 VanDerWaalsContact O-N 3.1Å
140S92.9Very high88.8Confident64 Ų6469.2 Ų69.245%0.44836%0.358SS..Hα-helixtrans-57.6-41.1-173.459.60000113.2S138 I142 Q143 Q144S138-S140 PolarHBondContact O-N 3.22Å; S140-I142 VanDerWaalsContact C-N 3.31Å; S140-I142 PolarHBondContact O-N 3.03Å; S140-Q143 PolarHBondContact O-N 3.05Å; S140-Q144 WeakPolarHBondContact O-CB 3.2Å; S140-Q144 VanDerWaalsContact O-CG 3.28Å; S140-Q144 WeakPolarHBondContact O-CG 3.05Å; S140-Q144 PolarHBondContact O-N 2.89Å
141L92.8Very high88.6Confident22 Ų2269.2 Ų69.212%0.11536%0.358CS..Hα-helixtrans-59.5-41.1175.8-173.467.9000111.9V34 T52 F54 L59 H139 T145 F153V34-L141 HydrophobicContact CG1-CD2 4.31Å; T52-L141 HydrophobicContact CG2-CD1 4.24Å; T52-L141 HydrophobicContact CG2-CD2 4.14Å; F54-L141 HydrophobicContact CB-CD2 4.31Å; F54-L141 HydrophobicContact CD2-CD2 3.77Å; F54-L141 HydrophobicContact CE2-CD2 4.48Å; F54-L141 HydrophobicContact CG-CD2 4.28Å; L59-L141 HydrophobicContact CD1-CD2 4.34Å; L59-L141 HydrophobicContact CD2-CD2 4.28Å; H139-L141 VanDerWaalsContact C-N 3.32Å; H139-L141 VanDerWaalsContact ND1-CB 3.35Å; H139-L141 WeakPolarHBondContact ND1-CB 3.2Å; H139-L141 PolarHBondContact ND1-N 3.29Å; H139-L141 VanDerWaalsContact ND1-N 3.16Å; H139-L141 PolarHBondContact O-N 2.95Å; L141-T145 VanDerWaalsContact O-CB 3.27Å; L141-T145 WeakPolarHBondContact O-CB 2.9Å; L141-T145 PolarHBondContact O-N 2.81Å; L141-T145 PolarHBondContact O-OG1 2.84Å; L141-F153 HydrophobicContact CD2-CE1 3.87Å; L141-F153 HydrophobicContact CD2-CZ 4.16Å; L141-F153 HydrophobicContact CG-CE1 3.88Å; L141-F153 HydrophobicContact CG-CZ 3.83Å
142I92.6Very high88.6Confident1 Ų160.8 Ų60.81%0.00532%0.321CS..Hα-helixtrans-68.3-46.7-179-69.1173000109.9L59 L135 D136 M137 H139 S140 T145 K146 F153 F241L59-I142 HydrophobicContact CB-CD1 4.21Å; L59-I142 HydrophobicContact CD1-CD1 4.41Å; L59-I142 HydrophobicContact CD1-CG1 4.37Å; L59-I142 HydrophobicContact CD2-CD1 4.44Å; L59-I142 HydrophobicContact CD2-CG1 4.5Å; L135-I142 HydrophobicContact CB-CD1 3.81Å; L135-I142 HydrophobicContact CD1-CD1 4.31Å; L135-I142 HydrophobicContact CG-CD1 4.5Å; D136-I142 VanDerWaalsContact O-CD1 3.31Å; D136-I142 WeakPolarHBondContact O-CD1 3.46Å; M137-I142 HydrophobicContact CE-CG2 3.89Å; M137-I142 HydrophobicContact SD-CG2 3.93Å; H139-I142 HydrophobicContact CB-CB 4.5Å; H139-I142 HydrophobicContact CB-CD1 4.16Å; H139-I142 HydrophobicContact CB-CG1 4.37Å; H139-I142 WeakPolarHBondContact O-CB 3.42Å; H139-I142 PolarHBondContact O-N 2.68Å; S140-I142 VanDerWaalsContact C-N 3.31Å; S140-I142 PolarHBondContact O-N 3.03Å; I142-T145 PolarHBondContact O-N 3.22Å; I142-K146 VanDerWaalsContact O-CB 3.31Å; I142-K146 WeakPolarHBondContact O-CB 3.36Å; I142-K146 PolarHBondContact O-N 2.95Å; I142-F153 HydrophobicContact CB-CE2 4.29Å; I142-F153 HydrophobicContact CG1-CE2 3.78Å; I142-F153 HydrophobicContact CG1-CZ 4.16Å; I142-F241 HydrophobicContact CG2-CE1 4.16Å
143Q90.7Very high88.9Confident97 Ų9757.2 Ų57.245%0.45328%0.284SS..Hα-helixtrans-58.6-51.2177.9-67.2-179.1-12.600111.7S138 H139 S140 T145 K146 E147S138-Q143 PolarHBondContact O-NE2 3.07Å; H139-Q143 PolarHBondContact O-N 2.72Å; H139-Q143 VanDerWaalsContact O-N 3.1Å; S140-Q143 PolarHBondContact O-N 3.05Å; Q143-T145 VanDerWaalsContact C-N 3.26Å; Q143-T145 PolarHBondContact O-N 2.76Å; Q143-K146 PolarHBondContact O-N 2.85Å; Q143-E147 WeakPolarHBondContact O-CG 3.13Å; Q143-E147 PolarHBondContact O-N 3.35Å; Q143-E147 VanDerWaalsContact O-N 3.08Å
144Q86.9Confident89Confident109 Ų10955 Ų5551%0.50928%0.276SS..Hα-helixtrans-63.3-30.8179.7-70.4178.27.500113.5S140S140-Q144 WeakPolarHBondContact O-CB 3.2Å; S140-Q144 VanDerWaalsContact O-CG 3.28Å; S140-Q144 WeakPolarHBondContact O-CG 3.05Å; S140-Q144 PolarHBondContact O-N 2.89Å
145T87.3Confident89Confident6 Ų652.6 Ų52.64%0.03726%0.262CS..Hα-helixtrans-80.2-39.5178.8-54.80000110.8V36 L141 I142 Q143 E147 K148 N151 F153 F241V36-T145 HydrophobicContact CG1-CG2 4.23Å; L141-T145 VanDerWaalsContact O-CB 3.27Å; L141-T145 WeakPolarHBondContact O-CB 2.9Å; L141-T145 PolarHBondContact O-N 2.81Å; L141-T145 PolarHBondContact O-OG1 2.84Å; I142-T145 PolarHBondContact O-N 3.22Å; Q143-T145 VanDerWaalsContact C-N 3.26Å; Q143-T145 PolarHBondContact O-N 2.76Å; T145-E147 PolarHBondContact O-N 2.91Å; T145-K148 CarbonylContact O-C 3.59Å; T145-K148 PolarHBondContact O-N 3.3Å; T145-K148 VanDerWaalsContact O-N 3.09Å; T145-K148 VanDerWaalsContact O-O 3.05Å; T145-N151 HydrophobicContact CG2-CB 3.5Å; T145-F153 VanDerWaalsContact CB-CZ 3.48Å; T145-F153 HydrophobicContact CG2-CD1 4.37Å; T145-F153 HydrophobicContact CG2-CD2 4.36Å; T145-F153 HydrophobicContact CG2-CE1 3.97Å; T145-F153 HydrophobicContact CG2-CE2 4Å; T145-F153 HydrophobicContact CG2-CZ 3.77Å; T145-F153 VanDerWaalsContact OG1-CZ 3.26Å; T145-F153 WeakPolarHBondContact OG1-CZ 3.47Å; T145-F241 HydrophobicContact CG2-CE2 3.9Å; T145-F241 HydrophobicContact CG2-CZ 4.32Å
146K85.8Confident89Confident79 Ų7952.4 Ų52.434%0.34326%0.26SS..Hα-helixtrans-62.7-39.4177-174.9177.1-177.3174.70112.3M137 I142 Q143 K148 N227 F241M137-K146 HydrophobicContact CE-CD 4.48Å; I142-K146 VanDerWaalsContact O-CB 3.31Å; I142-K146 WeakPolarHBondContact O-CB 3.36Å; I142-K146 PolarHBondContact O-N 2.95Å; Q143-K146 PolarHBondContact O-N 2.85Å; K146-K148 PolarHBondContact O-N 2.94Å; K146-N227 PolarHBondContact NZ-OD1 3.47Å; K146-F241 HydrophobicContact CB-CD1 4.15Å; K146-F241 HydrophobicContact CB-CE1 3.99Å; K146-F241 HydrophobicContact CB-CE2 4.38Å; K146-F241 HydrophobicContact CB-CG 4.39Å; K146-F241 HydrophobicContact CB-CZ 4.09Å; K146-F241 HydrophobicContact CD-CD1 4.32Å; K146-F241 HydrophobicContact CG-CD1 4.02Å; K146-F241 HydrophobicContact CG-CE1 4.35Å; K146-F241 HydrophobicContact CG-CG 4.18Å
147E81.1Confident89Confident155 Ų15551.5 Ų51.572%0.72425%0.254SS*.THydrogen-bonded Turntrans-58.8-30.1174.2-73.7172.6-177.800112.3Q143 T145 Q149Q143-E147 WeakPolarHBondContact O-CG 3.13Å; Q143-E147 PolarHBondContact O-N 3.35Å; Q143-E147 VanDerWaalsContact O-N 3.08Å; T145-E147 PolarHBondContact O-N 2.91Å; E147-Q149 PolarHBondContact O-N 3.49Å
148K76.3Confident89.1Confident65 Ų6549.9 Ų49.928%0.28325%0.245SC..SBendtrans-93.391.2178.4-66174.4-173.8164.90110T145 K146 K150 N151 L313T145-K148 CarbonylContact O-C 3.59Å; T145-K148 PolarHBondContact O-N 3.3Å; T145-K148 VanDerWaalsContact O-N 3.09Å; T145-K148 VanDerWaalsContact O-O 3.05Å; K146-K148 PolarHBondContact O-N 2.94Å; K148-K150 PolarHBondContact O-N 3.01Å; K148-N151 HydrophobicContact CB-CB 4.26Å; K148-N151 PolarHBondContact O-N 3.36Å; K148-L313 HydrophobicContact CD-CD2 4.42Å
149Q69.6Low89.2Confident174 Ų17447.3 Ų47.381%0.81322%0.224SC*.THydrogen-bonded Turntrans-53.4-18.4-178.3-63-176.9-3.900115.5E147E147-Q149 PolarHBondContact O-N 3.49Å
150K76.6Confident89.3Confident105 Ų10545.9 Ų45.946%0.45722%0.217SC..THydrogen-bonded Turntrans-88.5-1.8176.4-70.6-171.7176.3-1780114.2K39 K148K39-K150 WeakPolarHBondContact CA-O 2.91Å; K39-K150 HydrophobicContact CB-CB 4.2Å; K39-K150 WeakPolarHBondContact CB-O 3.27Å; K39-K150 WeakPolarHBondContact CG-O 3.39Å; K39-K150 PolarHBondContact N-O 3.46Å; K148-K150 PolarHBondContact O-N 3.01Å
151N86.3Confident89.4Confident6 Ų642.9 Ų42.93%0.03220%0.196CC..EExtended strand (participates in β ladder)trans-101141.5-177.3-70.73.7000111.9V36 H38 T145 K148V36-N151 HydrophobicContact CG1-CB 3.85Å; H38-N151 PolarHBondContact CD2-OD1 3.21Å; H38-N151 PolarHBondContact NE2-ND2 3.17Å; H38-N151 PolarHBondContact NE2-OD1 2.67Å; T145-N151 HydrophobicContact CG2-CB 3.5Å; K148-N151 HydrophobicContact CB-CB 4.26Å; K148-N151 PolarHBondContact O-N 3.36Å
152V90.8Very high89.4Confident2 Ų241.9 Ų41.91%0.01219%0.191CC..EExtended strand (participates in β ladder)trans-127.2132.5177.2178.20000107.9K37 K39 E222K37-V152 HydrophobicContact CB-CB 4.38Å; K37-V152 PolarHBondContact N-O 3.4Å; K37-V152 PolarHBondContact O-N 3.13Å; K39-V152 HydrophobicContact CD-CG2 4.38Å; K39-V152 VanDerWaalsContact CE-CG2 3.42Å; K39-V152 HydrophobicContact CG-CG2 4.16Å; V152-E222 HydrophobicContact CG1-CB 4.13Å; V152-E222 HydrophobicContact CG1-CG 4.17Å
153F94.9Very high89.4Confident1 Ų143.7 Ų43.70%0.00420%0.202CC..EExtended strand (participates in β ladder)trans-77.1139.8168.6-76.9-54.5000110.5V34 V36 L141 I142 T145 L223 I225 F241V34-F153 HydrophobicContact CG1-CD1 3.46Å; V34-F153 VanDerWaalsContact CG1-CD1 3.46Å; V34-F153 HydrophobicContact CG1-CE1 3.82Å; V34-F153 HydrophobicContact CG1-CG 4.34Å; V36-F153 HydrophobicContact CG2-CD1 4Å; V36-F153 HydrophobicContact CG2-CE1 3.73Å; L141-F153 HydrophobicContact CD2-CE1 3.87Å; L141-F153 HydrophobicContact CD2-CZ 4.16Å; L141-F153 HydrophobicContact CG-CE1 3.88Å; L141-F153 HydrophobicContact CG-CZ 3.83Å; I142-F153 HydrophobicContact CB-CE2 4.29Å; I142-F153 HydrophobicContact CG1-CE2 3.78Å; I142-F153 HydrophobicContact CG1-CZ 4.16Å; T145-F153 VanDerWaalsContact CB-CZ 3.48Å; T145-F153 HydrophobicContact CG2-CD1 4.37Å; T145-F153 HydrophobicContact CG2-CD2 4.36Å; T145-F153 HydrophobicContact CG2-CE1 3.97Å; T145-F153 HydrophobicContact CG2-CE2 4Å; T145-F153 HydrophobicContact CG2-CZ 3.77Å; T145-F153 VanDerWaalsContact OG1-CZ 3.26Å; T145-F153 WeakPolarHBondContact OG1-CZ 3.47Å; F153-L223 HydrophobicContact CB-CB 4.31Å; F153-L223 HydrophobicContact CB-CD1 3.95Å; F153-L223 HydrophobicContact CB-CG 4.23Å; F153-L223 PolarHBondContact O-N 2.71Å; F153-I225 HydrophobicContact CB-CD1 4.16Å; F153-I225 HydrophobicContact CD2-CD1 3.55Å; F153-I225 HydrophobicContact CE2-CD1 4.46Å; F153-I225 HydrophobicContact CG-CD1 4.35Å; F153-F241 HydrophobicContact CD2-CE1 4.49Å; F153-F241 HydrophobicContact CD2-CE2 4.18Å; F153-F241 AromaticContact CD2-CZ 3.62Å; F153-F241 HydrophobicContact CD2-CZ 3.62Å; F153-F241 HydrophobicContact CE2-CE1 4.46Å; F153-F241 HydrophobicContact CE2-CE2 4.33Å; F153-F241 AromaticContact CE2-CZ 3.56Å; F153-F241 HydrophobicContact CE2-CZ 3.56Å
154A95.3Very high89.3Confident0 Ų045.3 Ų45.30%021%0.21CC..EExtended strand (participates in β ladder)trans-136.4162.9168.700000108.9V34 V35 I220 I221 E222V34-A154 WeakPolarHBondContact CA-O 3.49Å; V35-A154 PolarHBondContact N-O 2.97Å; V35-A154 PolarHBondContact O-N 3.32Å; A154-I220 HydrophobicContact CB-CB 4Å; A154-I220 HydrophobicContact CB-CD1 3.66Å; A154-I220 HydrophobicContact CB-CG1 4.3Å; A154-I221 CarbonylContact C-O 3.48Å; A154-I221 WeakPolarHBondContact CA-O 3.39Å; A154-I221 WeakPolarHBondContact CB-O 3.45Å; A154-E222 HydrophobicContact CB-CG 4.26Å
155I96.1Very high89.4Confident1 Ų145 Ų451%0.00522%0.218CC..EExtended strand (participates in β ladder)trans-123.2146.8174.463.6178.9000109.8L32 T33 V34 L56 L126 K157 I220 I221 L223 L233L32-I155 HydrophobicContact CD2-CD1 4Å; T33-I155 CarbonylContact O-C 3.55Å; T33-I155 VanDerWaalsContact O-CA 3.3Å; T33-I155 WeakPolarHBondContact O-CA 3.29Å; V34-I155 HydrophobicContact CG2-CG2 4.25Å; L56-I155 HydrophobicContact CB-CG2 4.2Å; L56-I155 HydrophobicContact CD1-CG2 4.43Å; L56-I155 HydrophobicContact CD2-CD1 4.04Å; L126-I155 HydrophobicContact CD2-CD1 3.98Å; I155-K157 PolarHBondContact O-N 3.44Å; I155-I220 CarbonylContact O-C 3.41Å; I155-I220 WeakPolarHBondContact O-CA 3.4Å; I155-I221 HydrophobicContact CD1-CG2 3.92Å; I155-I221 HydrophobicContact CG1-CG2 3.4Å; I155-I221 PolarHBondContact N-O 3.38Å; I155-I221 PolarHBondContact O-N 3.19Å; I155-L223 HydrophobicContact CD1-CD2 4.45Å; I155-L223 HydrophobicContact CG1-CD2 4.47Å; I155-L223 HydrophobicContact CG2-CD1 4.25Å; I155-L223 HydrophobicContact CG2-CD2 4.33Å; I155-L233 HydrophobicContact CD1-CD2 3.65Å; I155-L233 HydrophobicContact CG1-CD2 4.42Å
156V96.6Very high89.4Confident0 Ų045.5 Ų45.50%022%0.221CC..EExtended strand (participates in β ladder)trans-66.9117174.9179.80000109.4E30 L31 L32 T33 V35 E158 Y218E30-V156 VanDerWaalsContact O-CB 3.31Å; E30-V156 WeakPolarHBondContact O-CB 3.22Å; L31-V156 HydrophobicContact CD2-CG1 4.33Å; L32-V156 PolarHBondContact N-O 3.25Å; T33-V156 PolarHBondContact O-N 3.1Å; V35-V156 HydrophobicContact CG2-CG2 3.86Å; V156-E158 WeakPolarHBondContact CG1-O 3.31Å; V156-Y218 HydrophobicContact CG2-CD2 4.05Å
157K95.1Very high89.2Confident41 Ų4143.5 Ų43.518%0.17822%0.217CC..EExtended strand (participates in β ladder)trans-99.6-25177.976.9177.3-179.576.30112.8L31 A121 I155 G219 I220 I221L31-K157 WeakPolarHBondContact CD2-O 3.36Å; A121-K157 WeakPolarHBondContact CB-O 3.34Å; A121-K157 PolarHBondContact N-O 2.95Å; I155-K157 PolarHBondContact O-N 3.44Å; K157-G219 PolarHBondContact N-O 2.82Å; K157-I220 WeakPolarHBondContact CD-O 3.45Å; K157-I220 WeakPolarHBondContact CE-O 3.48Å; K157-I221 HydrophobicContact CB-CB 4.46Å; K157-I221 HydrophobicContact CB-CG2 4.15Å; K157-I221 HydrophobicContact CD-CB 4.16Å
158E95.4Very high89.2Confident10 Ų1036.1 Ų36.15%0.04718%0.182CC..EExtended strand (participates in β ladder)trans-150.7154.3-179.568.9-165150.700110.6L19 K118 H119 E120 V156 Y218 G219L19-E158 HydrophobicContact CD2-CG 4.39Å; K118-E158 WeakPolarHBondContact CE-OE2 3.4Å; K118-E158 IonicContact NZ-OE2 3.02Å; K118-E158 PolarHBondContact NZ-OE2 2.86Å; H119-E158 CarbonylContact O-C 3.58Å; H119-E158 WeakPolarHBondContact O-CA 3.41Å; E120-E158 HydrophobicContact CB-CB 4.26Å; E120-E158 HydrophobicContact CG-CB 4.19Å; V156-E158 WeakPolarHBondContact CG1-O 3.31Å; E158-Y218 CarbonylContact O-C 2.91Å; E158-Y218 VanDerWaalsContact O-CA 3.29Å; E158-Y218 WeakPolarHBondContact O-CA 3.47Å; E158-Y218 WeakPolarHBondContact O-CB 3.31Å; E158-G219 PolarHBondContact N-O 3.05Å; E158-G219 PolarHBondContact O-N 2.91Å
159R96Very high89.3Confident24 Ų2434.9 Ų34.99%0.09118%0.178CC..EExtended strand (participates in β ladder)trans-150.1147.9177.162-179.1-174.4160.1-3.7112.2M29 E30 K118 H119 V161 T215 A217M29-R159 WeakPolarHBondContact O-CD 3.38Å; M29-R159 PolarHBondContact O-NH1 2.97Å; M29-R159 VanDerWaalsContact O-NH1 3.17Å; E30-R159 VanDerWaalsContact CD-NH2 3.31Å; E30-R159 IonicContact OE1-CZ 2.54Å; E30-R159 IonicContact OE1-NH1 3.37Å; E30-R159 PolarHBondContact OE1-NH1 3.09Å; E30-R159 IonicContact OE1-NH2 2.68Å; E30-R159 PolarHBondContact OE1-NH2 3Å; E30-R159 IonicContact OE2-CZ 3.19Å; E30-R159 IonicContact OE2-NH1 2.78Å; E30-R159 PolarHBondContact OE2-NH1 3.42Å; E30-R159 IonicContact OE2-NH2 2.72Å; E30-R159 PolarHBondContact OE2-NH2 2.7Å; K118-R159 WeakPolarHBondContact CA-O 3.03Å; H119-R159 HydrophobicContact CB-CG 3.81Å; H119-R159 PolarHBondContact N-O 3.43Å; H119-R159 PolarHBondContact O-N 3.15Å; R159-V161 HydrophobicContact CG-CG1 4.07Å; R159-T215 HydrophobicContact CB-CG2 3.79Å; R159-A217 CarbonylContact C-O 3.27Å; R159-A217 WeakPolarHBondContact CA-O 3.32Å
160I95.9Very high89.5Confident1 Ų129 Ų291%0.00515%0.151CC..EExtended strand (participates in β ladder)trans-103.4123.1174.1-50.5-57.5000108.1F9 L19 F75 L116 K117 K118 T215 I216 A217F9-I160 HydrophobicContact CE1-CG2 4.28Å; F9-I160 HydrophobicContact CZ-CG2 4.02Å; L19-I160 HydrophobicContact CD1-CG1 4.11Å; F75-I160 HydrophobicContact CD1-CD1 4.06Å; F75-I160 HydrophobicContact CD1-CG2 4.05Å; F75-I160 HydrophobicContact CE1-CD1 4.18Å; F75-I160 HydrophobicContact CG-CD1 4.27Å; F75-I160 HydrophobicContact CZ-CD1 4.47Å; L116-I160 HydrophobicContact CB-CG2 4Å; L116-I160 HydrophobicContact CD1-CG2 4.1Å; L116-I160 HydrophobicContact CG-CG2 4.44Å; K117-I160 CarbonylContact O-C 3.48Å; K117-I160 WeakPolarHBondContact O-CA 3.32Å; K118-I160 HydrophobicContact CB-CD1 3.74Å; K118-I160 HydrophobicContact CD-CD1 4.27Å; K118-I160 HydrophobicContact CG-CD1 3.73Å; I160-T215 CarbonylContact O-C 3.57Å; I160-T215 WeakPolarHBondContact O-CA 3.33Å; I160-I216 HydrophobicContact CB-CG1 4.04Å; I160-I216 HydrophobicContact CG2-CD1 3.99Å; I160-I216 HydrophobicContact CG2-CG1 3.89Å; I160-I216 WeakPolarHBondContact O-CG1 3.46Å; I160-I216 PolarHBondContact O-N 2.74Å; I160-A217 HydrophobicContact CB-CB 4.31Å; I160-A217 HydrophobicContact CG1-CB 4.18Å; I160-A217 PolarHBondContact N-O 3.06Å
161V95.4Very high89Confident2 Ų226.2 Ų26.21%0.01214%0.141CC..EExtended strand (participates in β ladder)trans-122.4146.4-173.9-60.90000112.1L116 K117 R159 T214L116-V161 WeakPolarHBondContact CA-O 3.4Å; K117-V161 HydrophobicContact CB-CG2 3.96Å; K117-V161 PolarHBondContact N-O 2.84Å; K117-V161 PolarHBondContact O-N 2.86Å; R159-V161 HydrophobicContact CG-CG1 4.07Å; V161-T214 CarbonylContact C-O 3.56Å; V161-T214 VanDerWaalsContact CA-O 3.29Å; V161-T214 WeakPolarHBondContact CA-O 3.49Å
162T93.6Very high87.8Confident0 Ų027.2 Ų27.20%015%0.147CC..EExtended strand (participates in β ladder)trans-70.3145.9170.761.70000110.6L116 I210 P211 P212 H213 T214 I216L116-T162 HydrophobicContact CD2-CG2 4.12Å; T162-I210 HydrophobicContact CG2-CG2 4.29Å; T162-P211 PolarHBondContact OG1-O 3.3Å; T162-P212 WeakPolarHBondContact OG1-CA 3.3Å; T162-H213 VanDerWaalsContact O-CA 3.28Å; T162-H213 WeakPolarHBondContact O-CA 3.48Å; T162-H213 PolarHBondContact O-N 3.42Å; T162-H213 PolarHBondContact OG1-N 3.16Å; T162-H213 VanDerWaalsContact OG1-N 3.14Å; T162-T214 PolarHBondContact N-O 3.21Å; T162-T214 PolarHBondContact OG1-N 2.7Å; T162-I216 HydrophobicContact CG2-CG2 3.95Å
163T91.4Very high86.1Confident39 Ų3932 Ų3224%0.23917%0.169CC..SBendtrans-102.3-20.5177.960.20000113.2S115 K117S115-T163 WeakPolarHBondContact O-CB 3.45Å; S115-T163 WeakPolarHBondContact O-CG2 3.39Å; S115-T163 PolarHBondContact O-N 2.91Å; S115-T163 PolarHBondContact O-OG1 3.23Å; K117-T163 HydrophobicContact CB-CG2 4.14Å; K117-T163 HydrophobicContact CD-CG2 3.73Å; K117-T163 HydrophobicContact CG-CG2 3.63Å
164Q88.4Confident83.6Confident131 Ų13135.7 Ų35.761%0.61219%0.187SC*.SBendtrans-140.7159.2-175.9-63.9-175.91.900109.2C166Q164-C166 PolarHBondContact O-N 2.69Å
165P89.2Confident80.8Confident104 Ų10440.2 Ų40.268%0.67521%0.208SC*.  trans-51.9134.8167.1-19.928.2000110.7I210P165-I210 CarbonylContact C-O 3.59Å; P165-I210 WeakPolarHBondContact CA-O 3.27Å
166C87.1Confident78Confident15 Ų1542.2 Ų42.210%0.10123%0.229CC..EExtended strand (participates in β ladder)trans-143.7177.4-177.569.50000110.8S112 Q164 I210S112-C166 VanDerWaalsContact O-CB 3.26Å; S112-C166 WeakPolarHBondContact O-CB 3.48Å; Q164-C166 PolarHBondContact O-N 2.69Å; C166-I210 PolarHBondContact N-O 2.99Å; C166-I210 PolarHBondContact O-N 3.16Å
167S82.7Confident74.8Confident37 Ų3749.4 Ų49.426%0.25927%0.267SS..EExtended strand (participates in β ladder)trans-147.3152.6-172.462.10000114.6S112 M208S112-S167 PolarHBondContact N-O 3.09Å; S112-S167 PolarHBondContact O-N 2.94Å; S112-S167 VanDerWaalsContact O-O 3.12Å; S167-M208 CarbonylContact C-O 3.54Å; S167-M208 VanDerWaalsContact CA-O 3.23Å; S167-M208 WeakPolarHBondContact CA-O 3.35Å; S167-M208 WeakPolarHBondContact CB-O 3.35Å
168V81.3Confident71.9Confident0 Ų054.6 Ų54.60%030%0.295CS..EExtended strand (participates in β ladder)trans-121.6128.5170.1178.40000107.4M1 A5 L109 Q110 F113 M208 I210M1-V168 HydrophobicContact CB-CG1 4.17Å; A5-V168 HydrophobicContact CB-CG1 4.01Å; A5-V168 HydrophobicContact CB-CG2 3.7Å; L109-V168 HydrophobicContact CD1-CG1 3.51Å; L109-V168 HydrophobicContact CG-CG1 4.07Å; Q110-V168 CarbonylContact O-C 3.45Å; Q110-V168 WeakPolarHBondContact O-CA 3.47Å; F113-V168 HydrophobicContact CE1-CG2 4.16Å; F113-V168 HydrophobicContact CZ-CG2 4.47Å; V168-M208 PolarHBondContact N-O 3.08Å; V168-M208 PolarHBondContact O-N 3.29Å; V168-I210 HydrophobicContact CG2-CD1 3.77Å
169I77.4Confident68.8Low40 Ų4059 Ų5921%0.20533%0.333CS..EExtended strand (participates in β ladder)trans-119.4127.1-175.4-55.8171.9000107.9L109 Q110 V206 T207L109-I169 CarbonylContact C-O 3.49Å; L109-I169 WeakPolarHBondContact CA-O 3.34Å; Q110-I169 HydrophobicContact CB-CB 4.4Å; Q110-I169 PolarHBondContact N-O 3.21Å; Q110-I169 PolarHBondContact O-N 3.38Å; I169-V206 WeakPolarHBondContact CA-O 3.43Å; I169-T207 HydrophobicContact CG1-CG2 4.06Å
170E73.2Confident65.7Low49 Ų4961.5 Ų61.523%0.22937%0.367CS..EExtended strand (participates in β ladder)trans-111111.5171.2-172.5173.3-174.400109.5M1 K108 L109 V172 N205 V206M1-E170 HydrophobicContact CG-CB 3.88Å; M1-E170 WeakPolarHBondContact CG-OE2 3.41Å; M1-E170 HydrophobicContact SD-CB 3.57Å; M1-E170 VanDerWaalsContact SD-CB 3.57Å; K108-E170 CarbonylContact O-C 3.59Å; K108-E170 WeakPolarHBondContact O-CA 3.14Å; L109-E170 HydrophobicContact CD1-CB 3.91Å; L109-E170 HydrophobicContact CD1-CG 4.35Å; E170-V172 HydrophobicContact CG-CG2 4.07Å; E170-N205 CarbonylContact O-C 3.56Å; E170-N205 WeakPolarHBondContact O-CA 3.43Å; E170-V206 PolarHBondContact N-O 2.97Å; E170-V206 PolarHBondContact O-N 3.42Å
171D67.4Low62.4Low48 Ų4866.2 Ų66.226%0.25740%0.4SS..EExtended strand (participates in β ladder)trans-90.2111.8173.9-66.7-22.9000108.8S107 K108 N205S107-D171 CarbonylContact C-O 3.49Å; S107-D171 VanDerWaalsContact CA-O 3.26Å; S107-D171 WeakPolarHBondContact CA-O 3.32Å; K108-D171 HydrophobicContact CB-CB 4.31Å; K108-D171 PolarHBondContact N-O 3.5Å; K108-D171 PolarHBondContact O-N 3.09Å; D171-N205 PolarHBondContact OD1-ND2 3.02Å; D171-N205 PolarHBondContact OD1-OD1 3.21Å
172V60.7Low59.3Low27 Ų2774.6 Ų74.616%0.16444%0.444CS..EExtended strand (participates in β ladder)trans-104.3118.4176.8-175.30000109.2E170 S204E170-V172 HydrophobicContact CG-CG2 4.07Å; V172-S204 PolarHBondContact N-O 3.19Å; V172-S204 PolarHBondContact O-N 3.14Å; V172-S204 VanDerWaalsContact O-N 3.16Å
173Q55Low56.4Low101 Ų10181.3 Ų81.347%0.47248%0.478SS..EExtended strand (participates in β ladder)trans-102.5113.2169.8-66.4-173.7-22.400109.2S106S106-Q173 PolarHBondContact N-O 3.28Å; S106-Q173 VanDerWaalsContact N-O 3.13Å; S106-Q173 PolarHBondContact O-N 3.21Å
174Q43.5Very low53.5Low80 Ų8085.4 Ų85.437%0.37451%0.505SS..EExtended strand (participates in β ladder)trans-108.3126.3176.7-110.8173.111.900110.5D105 K202D105-Q174 WeakPolarHBondContact OD1-CG 3.2Å; D105-Q174 PolarHBondContact OD2-NE2 2.78Å; Q174-K202 PolarHBondContact N-O 2.94Å; Q174-K202 PolarHBondContact O-N 3.46Å
175Q35.7Very low50.7Low94 Ų9485 Ų8544%0.43952%0.515SS..EExtended strand (participates in β ladder)trans-114.692.5-178.2-170.9143.293.300111.8E104 K199E104-Q175 PolarHBondContact O-N 2.74Å; Q175-K199 HydrophobicContact CG-CD 4.49Å; Q175-K199 VanDerWaalsContact OE1-CE 3.32Å
176G37.1Very low47.8Very low43 Ų4384.7 Ų84.744%0.44352%0.522SS..EExtended strand (participates in β ladder)trans-95.1131179.700000113.9
177L30.4Very low45.4Very low152 Ų15289.7 Ų89.780%0.79655%0.554SS**  trans-97.6109.2160.3-89.8155.5000108.5A179L177-A179 PolarHBondContact O-N 2.86Å
178L33Very low42.9Very low150 Ų15097.3 Ų97.379%0.78558%0.583SS**  trans-81.697.7173.8-72.4174.1000110.3G180L178-G180 PolarHBondContact O-N 2.96Å
179A30.8Very low40.6Very low101 Ų101103 Ų10384%0.83563%0.629SS**  trans-80.798.2154.100000108.7L177L177-A179 PolarHBondContact O-N 2.86Å
180G31Very low38.6Very low77 Ų77103.3 Ų103.379%0.79464%0.635SS**SBendtrans41.485.515700000119.4L178L178-G180 PolarHBondContact O-N 2.96Å
181S27.1Very low36.5Very low100 Ų100109.9 Ų109.970%0.69966%0.663SS**  trans-157.5121.3144-165.10000110.4I183S181-I183 PolarHBondContact O-N 2.8Å
182L29.5Very low34.7Very low179 Ų179112.6 Ų112.694%0.93768%0.676SS**  trans-81.6105.8178.3-69.6163.2000109
183I32.3Very low33.3Very low141 Ų141116.5 Ų116.572%0.72370%0.695SS**  trans-122.8122.3162.7-55.9178.8000108.2S181S181-I183 PolarHBondContact O-N 2.8Å
184P29.8Very low32Very low124 Ų124118.1 Ų118.181%0.80571%0.707SS**  trans-89114.9-17932.6-28000110.5
185C31Very low31.9Very low122 Ų122117.3 Ų117.382%0.82471%0.707SS**  trans-138.5111.6162.3-80.70000109.2
186A28.6Very low31.9Very low99 Ų99122.5 Ų122.582%0.81873%0.732SS**  trans-94.7175.5172.800000110.7
187P36Very low31.8Very low119 Ų119127.7 Ų127.777%0.77375%0.749SS**  -120.5147.8-68.234.7-21.3000111.5
188K30.8Very low31.8Very low198 Ų198123.7 Ų123.786%0.86175%0.745SS**  trans-125125.5153.2-74.7-175.4-179.3176.50107.3S190K188-S190 PolarHBondContact O-N 3.08Å; K188-S190 PolarHBondContact O-OG 3.41Å
189A32.1Very low31.7Very low118 Ų118120.7 Ų120.798%0.97573%0.725SS**  trans-53.5100.3-170.200000111.5
190S34.7Very low32Very low47 Ų47119.2 Ų119.233%0.32970%0.703SS.*  trans-116.9134.4164.336.50000106K188 I192K188-S190 PolarHBondContact O-N 3.08Å; K188-S190 PolarHBondContact O-OG 3.41Å; S190-I192 PolarHBondContact O-N 3.48Å
191K29.5Very low32.5Very low187 Ų187116.9 Ų116.981%0.81367%0.674SS**  trans-68.199.5174.5-83.8178176.5173.70107.3L193K191-L193 PolarHBondContact O-N 3.23Å
192I30.7Very low33.3Very low105 Ų105116.8 Ų116.854%0.53866%0.662SS.*EExtended strand (participates in β ladder)trans-78.6105.8171.6-66168.2000106.7S190 L194 L200S190-I192 PolarHBondContact O-N 3.48Å; I192-L194 HydrophobicContact CG2-CG 4.43Å; I192-L200 HydrophobicContact CG2-CD1 3.34Å
193L30.7Very low34.2Very low109 Ų109111.8 Ų111.857%0.57164%0.636SS**EExtended strand (participates in β ladder)trans-91.2108.1170.9-142.889.6000108.1K191 T195K191-L193 PolarHBondContact O-N 3.23Å; L193-T195 PolarHBondContact O-N 3.01Å
194L28.7Very low35.3Very low135 Ų135107 Ų10771%0.70762%0.615SS**EExtended strand (participates in β ladder)trans-79.7110.7167.9-81.2146.6000107.6I192I192-L194 HydrophobicContact CG2-CG 4.43Å
195T39.7Very low37.2Very low63 Ų63106.1 Ų106.139%0.38760%0.603SS.*  trans-79.6146.7166.156.30000109L193 N197 G198 K199L193-T195 PolarHBondContact O-N 3.01Å; T195-N197 PolarHBondContact O-N 3.42Å; T195-G198 PolarHBondContact O-N 3.41Å; T195-G198 VanDerWaalsContact O-N 3.14Å; T195-K199 PolarHBondContact OG1-O 2.9Å
196E35.7Very low39.3Very low203 Ų203103.5 Ų103.595%0.94958%0.584SS**THydrogen-bonded Turntrans-53.7-10.4-175.8-87.2-179.3139.300115
197N34.8Very low41.7Very low152 Ų152102.6 Ų102.681%0.81357%0.568SS**THydrogen-bonded Turntrans-99.617.9-179.3-62.7-16.7000114.6T195 K199T195-N197 PolarHBondContact O-N 3.42Å; N197-K199 VanDerWaalsContact C-N 3.28Å; N197-K199 PolarHBondContact O-N 3.31Å
198G31.1Very low44Very low68 Ų6899.5 Ų99.570%0.70154%0.544SS*.SBendtrans70.419.7175.100000114.9T195T195-G198 PolarHBondContact O-N 3.41Å; T195-G198 VanDerWaalsContact O-N 3.14Å
199K31.4Very low46.8Very low87 Ų8797.7 Ų97.738%0.37854%0.538SS..  trans-97.6120.4178.5-152.4178.2-161.8-168.40110Q175 T195 N197Q175-K199 HydrophobicContact CG-CD 4.49Å; Q175-K199 VanDerWaalsContact OE1-CE 3.32Å; T195-K199 PolarHBondContact OG1-O 2.9Å; N197-K199 VanDerWaalsContact C-N 3.28Å; N197-K199 PolarHBondContact O-N 3.31Å
200L37.4Very low49.5Very low70 Ų7092.2 Ų92.237%0.36649%0.493SS..EExtended strand (participates in β ladder)trans-89.5101.4176.6-17273.8000109I192I192-L200 HydrophobicContact CG2-CD1 3.34Å
201S41Very low52.2Low28 Ų2893.6 Ų93.620%0.19650%0.5CS..EExtended strand (participates in β ladder)trans-90.3126167.653.30000109.1
202K43.7Very low55.1Low99 Ų9987.1 Ų87.143%0.4348%0.477SS..EExtended strand (participates in β ladder)trans-105.9104.9171.1-173.1-178.6177.1-170.20108.1Q174Q174-K202 PolarHBondContact N-O 2.94Å; Q174-K202 PolarHBondContact O-N 3.46Å
203D48.8Very low58Low74 Ų7488.7 Ų88.740%0.39648%0.482SS..EExtended strand (participates in β ladder)trans-91.1118.2171.6-63.1-21.2000108.1
204S56.3Low61Low41 Ų4184.5 Ų84.529%0.28746%0.461SS..EExtended strand (participates in β ladder)trans-124.7116.5170.658.70000109.7V172V172-S204 PolarHBondContact N-O 3.19Å; V172-S204 PolarHBondContact O-N 3.14Å; V172-S204 VanDerWaalsContact O-N 3.16Å
205N68.6Low64.2Low104 Ų10478.7 Ų78.756%0.55643%0.432SS*.EExtended strand (participates in β ladder)trans-97.6122173.3-60.212.4000107.6E170 D171E170-N205 CarbonylContact O-C 3.56Å; E170-N205 WeakPolarHBondContact O-CA 3.43Å; D171-N205 PolarHBondContact OD1-ND2 3.02Å; D171-N205 PolarHBondContact OD1-OD1 3.21Å
206V75.9Confident66.8Low68 Ų6875.7 Ų75.741%0.41241%0.413SS..EExtended strand (participates in β ladder)trans-102.5117.4173-1690000107.6M1 I169 E170M1-V206 HydrophobicContact CE-CB 4.08Å; M1-V206 HydrophobicContact CE-CG1 3.37Å; M1-V206 HydrophobicContact SD-CB 4.06Å; M1-V206 HydrophobicContact SD-CG1 4.02Å; I169-V206 WeakPolarHBondContact CA-O 3.43Å; E170-V206 PolarHBondContact N-O 2.97Å; E170-V206 PolarHBondContact O-N 3.42Å
207T79Confident69.6Low80 Ų8066 Ų6649%0.49137%0.368SS..EExtended strand (participates in β ladder)trans-104.8131.1176.1-57.40000109.7I169I169-T207 HydrophobicContact CG1-CG2 4.06Å
208M83.4Confident72.6Confident54 Ų5459.1 Ų59.127%0.26633%0.33SS..EExtended strand (participates in β ladder)trans-111.5122.6171.2177.7176.3-80.500109.2M1 F2 L25 S167 V168M1-M208 HydrophobicContact CB-CE 4.42Å; M1-M208 HydrophobicContact CB-SD 4.39Å; M1-M208 HydrophobicContact CE-CB 4.01Å; M1-M208 HydrophobicContact CE-CE 4.02Å; M1-M208 HydrophobicContact SD-CB 4.47Å; F2-M208 HydrophobicContact CB-SD 3.68Å; L25-M208 HydrophobicContact CD1-SD 4.12Å; S167-M208 CarbonylContact C-O 3.54Å; S167-M208 VanDerWaalsContact CA-O 3.23Å; S167-M208 WeakPolarHBondContact CA-O 3.35Å; S167-M208 WeakPolarHBondContact CB-O 3.35Å; V168-M208 PolarHBondContact N-O 3.08Å; V168-M208 PolarHBondContact O-N 3.29Å
209E88.9Confident75.6Confident160 Ų16055.9 Ų55.975%0.74830%0.297SS*.EExtended strand (participates in β ladder)trans-90.8137.9173.8-63.8-173.9171.700110.4
210I89.4Confident78.6Confident2 Ų252.9 Ų52.91%0.0129%0.285CS..EExtended strand (participates in β ladder)trans-118.4120.4-178-61.1169.1000107.8F2 L25 F113 T162 P165 C166 V168 T214F2-I210 HydrophobicContact CD2-CD1 3.75Å; F2-I210 HydrophobicContact CD2-CG1 4.27Å; F2-I210 HydrophobicContact CE2-CD1 3.86Å; F2-I210 HydrophobicContact CE2-CG1 4.4Å; L25-I210 HydrophobicContact CD2-CG2 4.4Å; F113-I210 HydrophobicContact CD1-CD1 4.01Å; F113-I210 HydrophobicContact CE1-CD1 3.62Å; T162-I210 HydrophobicContact CG2-CG2 4.29Å; P165-I210 CarbonylContact C-O 3.59Å; P165-I210 WeakPolarHBondContact CA-O 3.27Å; C166-I210 PolarHBondContact N-O 2.99Å; C166-I210 PolarHBondContact O-N 3.16Å; V168-I210 HydrophobicContact CG2-CD1 3.77Å; I210-T214 HydrophobicContact CG2-CG2 3.81Å; I210-T214 WeakPolarHBondContact CG2-OG1 3.48Å
211P90.8Very high81.3Confident76 Ų7650.1 Ų50.149%0.49427%0.271SS..  trans-61.4160.6177.6-24.234.8000113.5T162 T214T162-P211 PolarHBondContact OG1-O 3.3Å; P211-T214 PolarHBondContact O-OG1 3.24Å
212P91.8Very high83.9Confident51 Ų5150.3 Ų50.333%0.33127%0.268SS..THydrogen-bonded Turntrans-62.3157.8166.330.1-35000110.5T162 T214T162-P212 WeakPolarHBondContact OG1-CA 3.3Å; P212-T214 PolarHBondContact O-N 3.46Å
213H91.9Very high86.3Confident139 Ų13945.6 Ų45.664%0.64425%0.248SC*.THydrogen-bonded Turntrans62.220.7-178.6-49.1-64.8000114.7T162T162-H213 VanDerWaalsContact O-CA 3.28Å; T162-H213 WeakPolarHBondContact O-CA 3.48Å; T162-H213 PolarHBondContact O-N 3.42Å; T162-H213 PolarHBondContact OG1-N 3.16Å; T162-H213 VanDerWaalsContact OG1-N 3.14Å
214T93.7Very high88.4Confident21 Ų2145.2 Ų45.213%0.12924%0.244CC..  trans-78.9130.4172.4-57.80000109.5F2 L25 V161 T162 I210 P211 P212F2-T214 HydrophobicContact CE2-CG2 4.44Å; F2-T214 HydrophobicContact CZ-CG2 4.24Å; L25-T214 HydrophobicContact CD2-CG2 3.62Å; V161-T214 CarbonylContact C-O 3.56Å; V161-T214 VanDerWaalsContact CA-O 3.29Å; V161-T214 WeakPolarHBondContact CA-O 3.49Å; T162-T214 PolarHBondContact N-O 3.21Å; T162-T214 PolarHBondContact OG1-N 2.7Å; I210-T214 HydrophobicContact CG2-CG2 3.81Å; I210-T214 WeakPolarHBondContact CG2-OG1 3.48Å; P211-T214 PolarHBondContact O-OG1 3.24Å; P212-T214 PolarHBondContact O-N 3.46Å
215T95.5Very high90.2Very high13 Ų1343.3 Ų43.38%0.0823%0.23CC..EExtended strand (participates in β ladder)trans-77.4126.5173.1-57.50000110.1V22 M29 R159 I160 A217V22-T215 HydrophobicContact CG2-CG2 3.87Å; V22-T215 WeakPolarHBondContact CG2-O 3.42Å; M29-T215 HydrophobicContact CB-CG2 3.78Å; M29-T215 HydrophobicContact CG-CG2 4.42Å; R159-T215 HydrophobicContact CB-CG2 3.79Å; I160-T215 CarbonylContact O-C 3.57Å; I160-T215 WeakPolarHBondContact O-CA 3.33Å; T215-A217 WeakPolarHBondContact CG2-O 3.36Å
216I94.1Very high91.3Very high0 Ų041.8 Ų41.80%022%0.219CC..EExtended strand (participates in β ladder)trans-107.7-24.7-179.962.3167.6000112.9F2 T6 F9 V22 F113 L116 I160 T162F2-I216 HydrophobicContact CE2-CG2 4.4Å; F2-I216 HydrophobicContact CZ-CG2 4.44Å; T6-I216 WeakPolarHBondContact CB-O 3.46Å; T6-I216 HydrophobicContact CG2-CB 4.02Å; T6-I216 HydrophobicContact CG2-CG2 4.44Å; T6-I216 WeakPolarHBondContact CG2-O 3.39Å; F9-I216 HydrophobicContact CD1-CD1 3.81Å; F9-I216 HydrophobicContact CD1-CG1 4.37Å; F9-I216 HydrophobicContact CD2-CD1 4.26Å; F9-I216 HydrophobicContact CE1-CD1 3.58Å; F9-I216 HydrophobicContact CE1-CG1 4.09Å; F9-I216 HydrophobicContact CE2-CD1 4.04Å; F9-I216 HydrophobicContact CG-CD1 4.15Å; F9-I216 HydrophobicContact CZ-CD1 3.7Å; V22-I216 PolarHBondContact N-O 3.15Å; F113-I216 HydrophobicContact CB-CD1 4.4Å; F113-I216 HydrophobicContact CD1-CG2 4.12Å; F113-I216 HydrophobicContact CD2-CD1 4.06Å; F113-I216 HydrophobicContact CE1-CG2 4.11Å; F113-I216 HydrophobicContact CG-CD1 4.14Å; L116-I216 HydrophobicContact CD1-CD1 3.61Å; L116-I216 HydrophobicContact CD2-CD1 3.7Å; L116-I216 HydrophobicContact CG-CD1 4.29Å; I160-I216 HydrophobicContact CB-CG1 4.04Å; I160-I216 HydrophobicContact CG2-CD1 3.99Å; I160-I216 HydrophobicContact CG2-CG1 3.89Å; I160-I216 WeakPolarHBondContact O-CG1 3.46Å; I160-I216 PolarHBondContact O-N 2.74Å; T162-I216 HydrophobicContact CG2-CG2 3.95Å
217A95.1Very high92Very high0 Ų041 Ų410%021%0.212CC..EExtended strand (participates in β ladder)trans-151.8155.1174.700000110F9 V10 L19 I20 R159 I160 T215F9-A217 HydrophobicContact CD1-CB 4.46Å; F9-A217 HydrophobicContact CE1-CB 4.16Å; V10-A217 HydrophobicContact CG2-CB 3.64Å; L19-A217 HydrophobicContact CB-CB 4.42Å; I20-A217 CarbonylContact O-C 3.51Å; I20-A217 VanDerWaalsContact O-CA 3.25Å; I20-A217 WeakPolarHBondContact O-CA 3.48Å; R159-A217 CarbonylContact C-O 3.27Å; R159-A217 WeakPolarHBondContact CA-O 3.32Å; I160-A217 HydrophobicContact CB-CB 4.31Å; I160-A217 HydrophobicContact CG1-CB 4.18Å; I160-A217 PolarHBondContact N-O 3.06Å; T215-A217 WeakPolarHBondContact CG2-O 3.36Å
218Y96Very high92.6Very high6 Ų641.7 Ų41.72%0.02421%0.213CC..EExtended strand (participates in β ladder)trans-144.5155.3179.765.9-78.5000111.4I20 V22 M29 V35 Y49 V156 E158 I220I20-Y218 HydrophobicContact CB-CD1 4.25Å; I20-Y218 HydrophobicContact CB-CD2 4.45Å; I20-Y218 HydrophobicContact CB-CE1 3.84Å; I20-Y218 HydrophobicContact CB-CE2 4.08Å; I20-Y218 HydrophobicContact CD1-CD2 4.33Å; I20-Y218 HydrophobicContact CD1-CE2 3.77Å; I20-Y218 HydrophobicContact CG2-CE1 3.67Å; I20-Y218 HydrophobicContact CG2-CE2 4.26Å; I20-Y218 WeakPolarHBondContact CG2-OH 3.39Å; I20-Y218 PolarHBondContact N-O 2.78Å; I20-Y218 VanDerWaalsContact O-CD1 3.32Å; I20-Y218 WeakPolarHBondContact O-CD1 3.39Å; I20-Y218 PolarHBondContact O-N 3.32Å; V22-Y218 HydrophobicContact CG2-CD1 3.76Å; V22-Y218 HydrophobicContact CG2-CE1 4.22Å; M29-Y218 HydrophobicContact CE-CD1 3.79Å; M29-Y218 HydrophobicContact CE-CE1 3.27Å; M29-Y218 HydrophobicContact CE-CE2 4.41Å; M29-Y218 HydrophobicContact CG-CD1 4.28Å; M29-Y218 HydrophobicContact SD-CD1 4.02Å; M29-Y218 HydrophobicContact SD-CD2 4.41Å; M29-Y218 HydrophobicContact SD-CE1 3.98Å; M29-Y218 HydrophobicContact SD-CE2 4.35Å; M29-Y218 HydrophobicContact SD-CG 4.24Å; V35-Y218 HydrophobicContact CG2-CE2 4.26Å; Y49-Y218 VanDerWaalsContact CB-OH 3.31Å; Y49-Y218 WeakPolarHBondContact CB-OH 3.4Å; V156-Y218 HydrophobicContact CG2-CD2 4.05Å; E158-Y218 CarbonylContact O-C 2.91Å; E158-Y218 VanDerWaalsContact O-CA 3.29Å; E158-Y218 WeakPolarHBondContact O-CA 3.47Å; E158-Y218 WeakPolarHBondContact O-CB 3.31Å; Y218-I220 HydrophobicContact CD2-CG2 3.73Å; Y218-I220 HydrophobicContact CE2-CG2 3.68Å
219G94.6Very high93.1Very high0 Ų039.1 Ų39.10%020%0.2CC..EExtended strand (participates in β ladder)trans-119.5150171.200000110K157 E158K157-G219 PolarHBondContact N-O 2.82Å; E158-G219 PolarHBondContact N-O 3.05Å; E158-G219 PolarHBondContact O-N 2.91Å
220I94.7Very high93.3Very high25 Ų2535.3 Ų35.313%0.12818%0.182CC..EExtended strand (participates in β ladder)trans-119.5164.2-174.361.1166.4000112.1I20 V35 Y49 A154 I155 K157 Y218I20-I220 HydrophobicContact CD1-CD1 4.09Å; I20-I220 HydrophobicContact CD1-CG1 3.98Å; I20-I220 HydrophobicContact CD1-CG2 4.1Å; V35-I220 HydrophobicContact CG2-CG2 4.32Å; Y49-I220 HydrophobicContact CD1-CD1 3.84Å; Y49-I220 HydrophobicContact CE1-CD1 3.36Å; A154-I220 HydrophobicContact CB-CB 4Å; A154-I220 HydrophobicContact CB-CD1 3.66Å; A154-I220 HydrophobicContact CB-CG1 4.3Å; I155-I220 CarbonylContact O-C 3.41Å; I155-I220 WeakPolarHBondContact O-CA 3.4Å; K157-I220 WeakPolarHBondContact CD-O 3.45Å; K157-I220 WeakPolarHBondContact CE-O 3.48Å; Y218-I220 HydrophobicContact CD2-CG2 3.73Å; Y218-I220 HydrophobicContact CE2-CG2 3.68Å
221I94.1Very high93.5Very high12 Ų1235.9 Ų35.96%0.06219%0.185CC..EExtended strand (participates in β ladder)trans-127.6130.9162.2-172.7160.1000109.1V123 A154 I155 K157 L233 C234 V235V123-I221 HydrophobicContact CG1-CD1 4.12Å; A154-I221 CarbonylContact C-O 3.48Å; A154-I221 WeakPolarHBondContact CA-O 3.39Å; A154-I221 WeakPolarHBondContact CB-O 3.45Å; I155-I221 HydrophobicContact CD1-CG2 3.92Å; I155-I221 HydrophobicContact CG1-CG2 3.4Å; I155-I221 PolarHBondContact N-O 3.38Å; I155-I221 PolarHBondContact O-N 3.19Å; K157-I221 HydrophobicContact CB-CB 4.46Å; K157-I221 HydrophobicContact CB-CG2 4.15Å; K157-I221 HydrophobicContact CD-CB 4.16Å; I221-L233 HydrophobicContact CD1-CB 3.66Å; I221-L233 HydrophobicContact CG1-CB 4.04Å; I221-L233 HydrophobicContact CG2-CD2 4.24Å; I221-C234 WeakPolarHBondContact CG1-O 3.47Å; I221-V235 HydrophobicContact CD1-CG2 4.23Å
222E95.3Very high93.6Very high32 Ų3237.3 Ų37.315%0.1519%0.185CC..EExtended strand (participates in β ladder)trans-76.7153.9-178-65.8178.9-165.900111.7K37 V152 A154 C234 G239K37-E222 VanDerWaalsContact CD-OE1 3.26Å; K37-E222 WeakPolarHBondContact CD-OE1 3.46Å; K37-E222 WeakPolarHBondContact CE-OE1 3.42Å; K37-E222 IonicContact NZ-OE1 3.62Å; K37-E222 PolarHBondContact NZ-OE1 2.95Å; V152-E222 HydrophobicContact CG1-CB 4.13Å; V152-E222 HydrophobicContact CG1-CG 4.17Å; A154-E222 HydrophobicContact CB-CG 4.26Å; E222-C234 HydrophobicContact CB-CB 4.1Å; E222-C234 WeakPolarHBondContact O-CB 3.25Å; E222-C234 PolarHBondContact O-N 3.49Å; E222-G239 PolarHBondContact OE2-N 3.29Å
223L94.7Very high93.7Very high0 Ų035.3 Ų35.30%017%0.171CC..EExtended strand (participates in β ladder)trans-105.2132.6175-51.3-172.9000110.1L56 F153 I155 I225 F231 E232 L233 G239 G240L56-L223 HydrophobicContact CD1-CD1 4.36Å; F153-L223 HydrophobicContact CB-CB 4.31Å; F153-L223 HydrophobicContact CB-CD1 3.95Å; F153-L223 HydrophobicContact CB-CG 4.23Å; F153-L223 PolarHBondContact O-N 2.71Å; I155-L223 HydrophobicContact CD1-CD2 4.45Å; I155-L223 HydrophobicContact CG1-CD2 4.47Å; I155-L223 HydrophobicContact CG2-CD1 4.25Å; I155-L223 HydrophobicContact CG2-CD2 4.33Å; L223-I225 HydrophobicContact CB-CD1 4.14Å; L223-I225 HydrophobicContact CB-CG1 3.97Å; L223-I225 HydrophobicContact CD1-CD1 4.44Å; L223-F231 HydrophobicContact CD2-CD2 4.23Å; L223-E232 WeakPolarHBondContact CA-O 3.36Å; L223-L233 HydrophobicContact CD2-CD2 3.35Å; L223-G239 CarbonylContact O-C 3.6Å; L223-G239 VanDerWaalsContact O-CA 3.3Å; L223-G239 WeakPolarHBondContact O-CA 3.41Å; L223-G240 PolarHBondContact O-N 3.23Å
224E93.3Very high93.7Very high66 Ų6629.3 Ų29.331%0.30815%0.145SC..EExtended strand (participates in β ladder)trans-97.6118.7161.4-176.4167.9-159.600107.5F231 E232 G240E224-F231 CarbonylContact O-C 3.49Å; E224-F231 WeakPolarHBondContact O-CA 3.31Å; E224-F231 WeakPolarHBondContact O-CB 3.34Å; E224-E232 PolarHBondContact N-O 2.79Å; E224-E232 PolarHBondContact O-N 2.83Å; E224-G240 CarbonylContact C-O 3.55Å; E224-G240 WeakPolarHBondContact CA-O 3.38Å
225I93.7Very high93.2Very high1 Ų133.2 Ų33.21%0.00517%0.168CC..EExtended strand (participates in β ladder)trans-118.3123.1-170.6-59.4166.7000109.3L135 M137 F153 L223 F231 G240 F241 E242L135-I225 HydrophobicContact CD1-CB 4.5Å; L135-I225 HydrophobicContact CD1-CD1 3.57Å; L135-I225 HydrophobicContact CD1-CG1 3.76Å; L135-I225 HydrophobicContact CD1-CG2 3.91Å; M137-I225 HydrophobicContact CE-CG2 4.41Å; M137-I225 HydrophobicContact SD-CG2 4.28Å; F153-I225 HydrophobicContact CB-CD1 4.16Å; F153-I225 HydrophobicContact CD2-CD1 3.55Å; F153-I225 HydrophobicContact CE2-CD1 4.46Å; F153-I225 HydrophobicContact CG-CD1 4.35Å; L223-I225 HydrophobicContact CB-CD1 4.14Å; L223-I225 HydrophobicContact CB-CG1 3.97Å; L223-I225 HydrophobicContact CD1-CD1 4.44Å; I225-F231 HydrophobicContact CG1-CB 3.99Å; I225-G240 PolarHBondContact N-O 2.73Å; I225-F241 HydrophobicContact CB-CD1 3.98Å; I225-F241 HydrophobicContact CB-CE1 4.16Å; I225-F241 HydrophobicContact CD1-CD1 4.45Å; I225-F241 HydrophobicContact CD1-CE1 3.88Å; I225-F241 HydrophobicContact CD1-CZ 4.07Å; I225-F241 HydrophobicContact CG2-CD1 4Å; I225-F241 HydrophobicContact CG2-CE1 4.01Å; I225-F241 CarbonylContact O-C 3.57Å; I225-F241 WeakPolarHBondContact O-CA 3.41Å; I225-E242 PolarHBondContact O-N 3.24Å
226K92.4Very high92Very high71 Ų7141.6 Ų41.631%0.30921%0.209SC..  trans-82.1163.7177.1-62.9-173.1-165.5160.50111.9D228 G229 Q230 E242K226-D228 VanDerWaalsContact CB-OD1 3.27Å; K226-D228 WeakPolarHBondContact CB-OD1 3.48Å; K226-D228 PolarHBondContact O-N 2.96Å; K226-G229 PolarHBondContact O-N 3.36Å; K226-Q230 HydrophobicContact CB-CB 4.27Å; K226-Q230 HydrophobicContact CD-CB 4.09Å; K226-Q230 HydrophobicContact CG-CB 4.42Å; K226-Q230 PolarHBondContact N-O 3.31Å; K226-E242 WeakPolarHBondContact CA-OE2 3.49Å; K226-E242 WeakPolarHBondContact CB-OE2 3.29Å
227N90.8Very high90.8Very high52 Ų5244.8 Ų44.828%0.27823%0.231SC..THydrogen-bonded Turntrans-61.4-25.2179.3-85.7-33.4000114K146 G229 E242 D244K146-N227 PolarHBondContact NZ-OD1 3.47Å; N227-G229 VanDerWaalsContact C-N 3.34Å; N227-E242 PolarHBondContact N-OE2 3.42Å; N227-D244 PolarHBondContact ND2-OD1 3.31Å; N227-D244 PolarHBondContact ND2-OD2 3.14Å
228D91Very high90.1Very high94 Ų9447.5 Ų47.550%0.50326%0.259SS..THydrogen-bonded Turntrans-894177.369.9-10.6000114K226 Q230K226-D228 VanDerWaalsContact CB-OD1 3.27Å; K226-D228 WeakPolarHBondContact CB-OD1 3.48Å; K226-D228 PolarHBondContact O-N 2.96Å; D228-Q230 VanDerWaalsContact C-N 3.32Å; D228-Q230 PolarHBondContact O-N 3.14Å; D228-Q230 WeakPolarHBondContact OD1-CB 3.41Å; D228-Q230 WeakPolarHBondContact OD1-CG 3.49Å; D228-Q230 PolarHBondContact OD1-N 3.09Å; D228-Q230 VanDerWaalsContact OD2-CD 3.27Å; D228-Q230 WeakPolarHBondContact OD2-CG 3.21Å; D228-Q230 PolarHBondContact OD2-NE2 3.38Å
229G92.6Very high89.6Confident0 Ų047.8 Ų47.80%026%0.264CS..SBendtrans83.9-3.5-179.200000114.9V134 L135 M137 K226 N227V134-G229 CarbonylContact C-O 3.57Å; V134-G229 VanDerWaalsContact CA-O 3.31Å; V134-G229 WeakPolarHBondContact CA-O 3.39Å; L135-G229 PolarHBondContact N-O 2.76Å; M137-G229 WeakPolarHBondContact SD-CA 3.27Å; K226-G229 PolarHBondContact O-N 3.36Å; N227-G229 VanDerWaalsContact C-N 3.34Å
230Q93.9Very high89.4Confident80 Ų8048 Ų4837%0.37427%0.267SS..BIsolated β-bridgetrans-59.9142.4166.7-68.1177.53000109.7V134 K226 D228V134-Q230 HydrophobicContact CG1-CG 3.98Å; K226-Q230 HydrophobicContact CB-CB 4.27Å; K226-Q230 HydrophobicContact CD-CB 4.09Å; K226-Q230 HydrophobicContact CG-CB 4.42Å; K226-Q230 PolarHBondContact N-O 3.31Å; D228-Q230 VanDerWaalsContact C-N 3.32Å; D228-Q230 PolarHBondContact O-N 3.14Å; D228-Q230 WeakPolarHBondContact OD1-CB 3.41Å; D228-Q230 WeakPolarHBondContact OD1-CG 3.49Å; D228-Q230 PolarHBondContact OD1-N 3.09Å; D228-Q230 VanDerWaalsContact OD2-CD 3.27Å; D228-Q230 WeakPolarHBondContact OD2-CG 3.21Å; D228-Q230 PolarHBondContact OD2-NE2 3.38Å
231F94.3Very high89.1Confident15 Ų1548.5 Ų48.57%0.06627%0.268CS..EExtended strand (participates in β ladder)trans-139.8156.6178.771.7-80.6000112.5L56 L60 R133 L135 L223 E224 I225 L233L56-F231 HydrophobicContact CD1-CE2 4.22Å; L56-F231 HydrophobicContact CD1-CZ 4.18Å; L56-F231 HydrophobicContact CD2-CE2 4.35Å; L56-F231 HydrophobicContact CD2-CZ 4.37Å; L60-F231 HydrophobicContact CD2-CE1 3.52Å; L60-F231 HydrophobicContact CD2-CZ 3.86Å; R133-F231 HydrophobicContact CB-CE1 3.99Å; R133-F231 HydrophobicContact CB-CZ 4.4Å; L135-F231 HydrophobicContact CD1-CB 4.26Å; L135-F231 HydrophobicContact CD1-CD1 4.35Å; L135-F231 HydrophobicContact CD1-CG 4.4Å; L135-F231 HydrophobicContact CD2-CD1 4.08Å; L135-F231 HydrophobicContact CD2-CE1 4.17Å; L135-F231 HydrophobicContact CG-CD1 3.76Å; L135-F231 HydrophobicContact CG-CE1 4.3Å; L135-F231 HydrophobicContact CG-CG 4.28Å; L223-F231 HydrophobicContact CD2-CD2 4.23Å; E224-F231 CarbonylContact O-C 3.49Å; E224-F231 WeakPolarHBondContact O-CA 3.31Å; E224-F231 WeakPolarHBondContact O-CB 3.34Å; I225-F231 HydrophobicContact CG1-CB 3.99Å; F231-L233 HydrophobicContact CE2-CD2 4.48Å
232E93.4Very high88.7Confident106 Ų10652.5 Ų52.550%0.49529%0.286SS..EExtended strand (participates in β ladder)trans-130.6142.9176.7-64.9-176.6-165.500110.6L223 E224L223-E232 WeakPolarHBondContact CA-O 3.36Å; E224-E232 PolarHBondContact N-O 2.79Å; E224-E232 PolarHBondContact O-N 2.83Å
233L93.4Very high87.8Confident9 Ų955.6 Ų55.65%0.04731%0.307CS..EExtended strand (participates in β ladder)trans-82.4122.2173.7-48.8169.6000109.4L126 M127 I155 I221 L223 F231 V235L126-L233 HydrophobicContact CB-CD1 4.43Å; L126-L233 HydrophobicContact CD2-CD1 3.83Å; L126-L233 HydrophobicContact CG-CD1 3.74Å; M127-L233 HydrophobicContact CG-CD1 3.99Å; M127-L233 HydrophobicContact SD-CB 3.46Å; M127-L233 WeakPolarHBondContact SD-CB 3.08Å; M127-L233 HydrophobicContact SD-CD1 3.59Å; M127-L233 VanDerWaalsContact SD-CD1 3.59Å; M127-L233 HydrophobicContact SD-CG 3.71Å; I155-L233 HydrophobicContact CD1-CD2 3.65Å; I155-L233 HydrophobicContact CG1-CD2 4.42Å; I221-L233 HydrophobicContact CD1-CB 3.66Å; I221-L233 HydrophobicContact CG1-CB 4.04Å; I221-L233 HydrophobicContact CG2-CD2 4.24Å; L223-L233 HydrophobicContact CD2-CD2 3.35Å; F231-L233 HydrophobicContact CE2-CD2 4.48Å; L233-V235 PolarHBondContact O-N 3.02Å
234C91.1Very high85.6Confident13 Ų1362.4 Ų62.49%0.08834%0.344CS..EExtended strand (participates in β ladder)trans-82.898.4-174.1-66.10000111.4I221 E222 S237I221-C234 WeakPolarHBondContact CG1-O 3.47Å; E222-C234 HydrophobicContact CB-CB 4.1Å; E222-C234 WeakPolarHBondContact O-CB 3.25Å; E222-C234 PolarHBondContact O-N 3.49Å; C234-S237 WeakPolarHBondContact CB-O 3.35Å
235V82.6Confident83.2Confident102 Ų10261.6 Ų61.662%0.61835%0.353SS*.SBendtrans-79.7-34.6177-175.90000112.1I221 L233I221-V235 HydrophobicContact CD1-CG2 4.23Å; L233-V235 PolarHBondContact O-N 3.02Å
236M72.1Confident80.5Confident189 Ų18971.4 Ų71.493%0.93140%0.398SS*.SBendtrans-135.4-10-174.9-61.6-173.864.600114.5
237S68.9Low77.9Confident68 Ų6872.1 Ų72.148%0.47641%0.412SS..SBendtrans-100.4168176.746.90000111.2C234C234-S237 WeakPolarHBondContact CB-O 3.35Å
238G79.6Confident75.1Confident56 Ų5679.2 Ų79.258%0.57744%0.441SS*.  trans-85141.6165.300000110.4
239G86.3Confident72.4Confident12 Ų1282.7 Ų82.712%0.12445%0.451CS..  trans-82.6-173176.500000113.6E222 L223E222-G239 PolarHBondContact OE2-N 3.29Å; L223-G239 CarbonylContact O-C 3.6Å; L223-G239 VanDerWaalsContact O-CA 3.3Å; L223-G239 WeakPolarHBondContact O-CA 3.41Å
240G90.3Very high69.4Low6 Ų687.7 Ų87.76%0.06249%0.486CS..EExtended strand (participates in β ladder)trans139.7-173.8178.500000112.6L223 E224 I225L223-G240 PolarHBondContact O-N 3.23Å; E224-G240 CarbonylContact C-O 3.55Å; E224-G240 WeakPolarHBondContact CA-O 3.38Å; I225-G240 PolarHBondContact N-O 2.73Å
241F87.9Confident66.4Low34 Ų3491.2 Ų91.215%0.14951%0.507CS..EExtended strand (participates in β ladder)trans-91.5142.7174-66.6-89.4000110.7I142 T145 K146 F153 I225 V243I142-F241 HydrophobicContact CG2-CE1 4.16Å; T145-F241 HydrophobicContact CG2-CE2 3.9Å; T145-F241 HydrophobicContact CG2-CZ 4.32Å; K146-F241 HydrophobicContact CB-CD1 4.15Å; K146-F241 HydrophobicContact CB-CE1 3.99Å; K146-F241 HydrophobicContact CB-CE2 4.38Å; K146-F241 HydrophobicContact CB-CG 4.39Å; K146-F241 HydrophobicContact CB-CZ 4.09Å; K146-F241 HydrophobicContact CD-CD1 4.32Å; K146-F241 HydrophobicContact CG-CD1 4.02Å; K146-F241 HydrophobicContact CG-CE1 4.35Å; K146-F241 HydrophobicContact CG-CG 4.18Å; F153-F241 HydrophobicContact CD2-CE1 4.49Å; F153-F241 HydrophobicContact CD2-CE2 4.18Å; F153-F241 AromaticContact CD2-CZ 3.62Å; F153-F241 HydrophobicContact CD2-CZ 3.62Å; F153-F241 HydrophobicContact CE2-CE1 4.46Å; F153-F241 HydrophobicContact CE2-CE2 4.33Å; F153-F241 AromaticContact CE2-CZ 3.56Å; F153-F241 HydrophobicContact CE2-CZ 3.56Å; I225-F241 HydrophobicContact CB-CD1 3.98Å; I225-F241 HydrophobicContact CB-CE1 4.16Å; I225-F241 HydrophobicContact CD1-CD1 4.45Å; I225-F241 HydrophobicContact CD1-CE1 3.88Å; I225-F241 HydrophobicContact CD1-CZ 4.07Å; I225-F241 HydrophobicContact CG2-CD1 4Å; I225-F241 HydrophobicContact CG2-CE1 4.01Å; I225-F241 CarbonylContact O-C 3.57Å; I225-F241 WeakPolarHBondContact O-CA 3.41Å; F241-V243 PolarHBondContact O-N 3.16Å
242E85.4Confident63.2Low97 Ų9799 Ų9945%0.45355%0.546SS..  trans-57.2131.4166.9-174.3173.5-151.200110I225 K226 N227I225-E242 PolarHBondContact O-N 3.24Å; K226-E242 WeakPolarHBondContact CA-OE2 3.49Å; K226-E242 WeakPolarHBondContact CB-OE2 3.29Å; N227-E242 PolarHBondContact N-OE2 3.42Å
243V76.4Confident60Low97 Ų9799.2 Ų99.259%0.58856%0.559SS**  trans-109.4129.2178.5-176.40000107.8F241 G245F241-V243 PolarHBondContact O-N 3.16Å; V243-G245 VanDerWaalsContact C-N 3.31Å; V243-G245 PolarHBondContact O-N 3.01Å
244D48.5Very low56.9Low143 Ų143102.9 Ų102.977%0.76559%0.59SS**SBendtrans-68.887.4173.8-69-44.3000109.9N227N227-D244 PolarHBondContact ND2-OD1 3.31Å; N227-D244 PolarHBondContact ND2-OD2 3.14Å
245G43.9Very low54.3Low49 Ų49107.5 Ų107.551%0.50562%0.623SS.*SBendtrans164145.5178.100000113.6V243 S247V243-G245 VanDerWaalsContact C-N 3.31Å; V243-G245 PolarHBondContact O-N 3.01Å; G245-S247 PolarHBondContact O-N 3.36Å; G245-S247 PolarHBondContact O-OG 2.81Å
246H35.9Very low51.7Low206 Ų206106.4 Ų106.495%0.95463%0.625SS**  trans-65.873.3178.5-75.968.6000111.9K248H246-K248 PolarHBondContact O-N 2.95Å
247S37.2Very low50Low87 Ų87103.5 Ų103.561%0.60862%0.62SS**  trans-81.5102.8169.5-51.10000106.6G245 K249G245-S247 PolarHBondContact O-N 3.36Å; G245-S247 PolarHBondContact O-OG 2.81Å; S247-K249 PolarHBondContact O-N 3.47Å
248K32.5Very low49.2Very low201 Ų201108 Ų10887%0.87463%0.631SS**  trans-50.9115.7169.5-79178.4177.3175.10107.5H246 S250H246-K248 PolarHBondContact O-N 2.95Å; K248-S250 VanDerWaalsContact C-N 3.33Å; K248-S250 PolarHBondContact O-N 2.87Å
249K34.7Very low47.7Very low166 Ų166111.1 Ų111.172%0.72263%0.634SS**  trans-54.2102.9165.9-74.6-172.3175.1-172.40106.1S247 L251S247-K249 PolarHBondContact O-N 3.47Å; K249-L251 PolarHBondContact O-N 3.14Å
250S30.3Very low46.5Very low105 Ų105115.3 Ų115.373%0.73465%0.654SS**  trans-70.987.2174.5-172.40000106.8K248 M252K248-S250 VanDerWaalsContact C-N 3.33Å; K248-S250 PolarHBondContact O-N 2.87Å; S250-M252 VanDerWaalsContact C-N 3.32Å; S250-M252 PolarHBondContact O-N 2.89Å
251L30.3Very low45.7Very low155 Ų155119.9 Ų119.981%0.81268%0.675SS**  trans-61.9100.9161-12097.7000105.7K249 S253K249-L251 PolarHBondContact O-N 3.14Å; L251-S253 VanDerWaalsContact C-N 3.34Å; L251-S253 PolarHBondContact O-N 3.23Å
252M26.3Very low45.2Very low179 Ų179119.5 Ų119.588%0.88268%0.675SS**  trans-70.399.3166.8-64.8-153.981.600107.3S250S250-M252 VanDerWaalsContact C-N 3.32Å; S250-M252 PolarHBondContact O-N 2.89Å
253S26.2Very low45.1Very low109 Ų109117.5 Ų117.576%0.76267%0.666SS**  trans-73.6141.8177.264.70000111.5L251L251-S253 VanDerWaalsContact C-N 3.34Å; L251-S253 PolarHBondContact O-N 3.23Å
254A29Very low45.4Very low86 Ų86118.3 Ų118.371%0.71166%0.663SS**  trans-19.1129.4168.500000119.1
255S35.5Very low47.3Very low110 Ų110112.1 Ų112.177%0.76963%0.63SS**  trans34.5101.2139.463.90000119.6
256A28.7Very low49.4Very low80 Ų80110.1 Ų110.166%0.66161%0.607SS**  trans-98.1162.7149.900000110.3K258A256-K258 PolarHBondContact O-N 3.2Å
257P36.5Very low51.9Low127 Ų127104.9 Ų104.983%0.82558%0.583SS**  trans-62.1131.7-175.6-14.128.4000111.2N259P257-N259 PolarHBondContact O-N 3.42Å
258K51.3Low54.5Low162 Ų162106.4 Ų106.470%0.70458%0.579SS**G310 helixtrans-80.53.6-155.9-67.2-179176.9177.80117A256 N260A256-K258 PolarHBondContact O-N 3.2Å; K258-N260 VanDerWaalsContact C-N 3.34Å; K258-N260 PolarHBondContact O-N 3.39Å
259N49.4Very low57.3Low122 Ų12297.3 Ų97.365%0.65254%0.54SS*.G310 helixtrans-77.8-16.3-172.8-72.212000114.2P257P257-N259 PolarHBondContact O-N 3.42Å
260N60.2Low60Low101 Ų10194.3 Ų94.354%0.5453%0.527SS..G310 helixtrans-112.54.2-175.4-58.91.4000113.8K258 T262 Q263 Q264K258-N260 VanDerWaalsContact C-N 3.34Å; K258-N260 PolarHBondContact O-N 3.39Å; N260-T262 PolarHBondContact O-N 2.93Å; N260-Q263 PolarHBondContact O-N 3.03Å; N260-Q264 WeakPolarHBondContact O-CB 3.49Å; N260-Q264 PolarHBondContact O-N 2.88Å
261M72.8Confident63Low101 Ų10194.5 Ų94.550%0.49852%0.52SS..Hα-helixtrans-62.6-45.5-175.9-172.169.2-175.100111.3Q263 Q264 E265M261-Q263 PolarHBondContact O-N 3.38Å; M261-Q264 PolarHBondContact O-N 3.34Å; M261-E265 HydrophobicContact CE-CG 4.01Å; M261-E265 VanDerWaalsContact CE-OE1 3.23Å; M261-E265 WeakPolarHBondContact CE-OE1 3.49Å; M261-E265 WeakPolarHBondContact O-CG 3.43Å; M261-E265 PolarHBondContact O-N 3.21Å
262T79Confident66Low26 Ų2689 Ų8916%0.1649%0.49CS..Hα-helixtrans-60.5-45-179.9-50.90000111.7N260 E265 L266 L445 C448N260-T262 PolarHBondContact O-N 2.93Å; T262-E265 PolarHBondContact O-N 2.9Å; T262-L266 HydrophobicContact CG2-CD1 4.14Å; T262-L266 WeakPolarHBondContact O-CB 3.44Å; T262-L266 VanDerWaalsContact O-CG 3.27Å; T262-L266 WeakPolarHBondContact O-CG 3.48Å; T262-L266 PolarHBondContact O-N 2.94Å; T262-L445 HydrophobicContact CG2-CB 4.42Å; T262-L445 HydrophobicContact CG2-CD1 3.88Å; T262-C448 HydrophobicContact CG2-CB 4.47Å
263Q81.7Confident69.2Low56 Ų5680.8 Ų80.826%0.26245%0.449SS..Hα-helixtrans-63.8-46.6177.6-172.2-177.97.600111.9N260 M261 E265 L266 E267 S394N260-Q263 PolarHBondContact O-N 3.03Å; M261-Q263 PolarHBondContact O-N 3.38Å; Q263-E265 VanDerWaalsContact C-N 3.26Å; Q263-E265 PolarHBondContact O-N 3.27Å; Q263-L266 PolarHBondContact O-N 2.89Å; Q263-E267 PolarHBondContact O-N 3.01Å; Q263-S394 WeakPolarHBondContact CB-O 3.31Å
264Q84.2Confident72.3Confident114 Ų11480.4 Ų80.453%0.53344%0.435SS..Hα-helixtrans-59.9-40.1-179.4-172.9179.45.900111.5N260 M261 K268N260-Q264 WeakPolarHBondContact O-CB 3.49Å; N260-Q264 PolarHBondContact O-N 2.88Å; M261-Q264 PolarHBondContact O-N 3.34Å; Q264-K268 WeakPolarHBondContact O-CG 3.47Å; Q264-K268 PolarHBondContact O-N 2.86Å
265E87.4Confident75.4Confident13 Ų1379.5 Ų79.56%0.06142%0.416CS..Hα-helixtrans-70.5-40.1176-65.7-52.2144.900112.7F43 M261 T262 Q263 E267 K268 L269 L445F43-E265 HydrophobicContact CE1-CB 4.31Å; F43-E265 HydrophobicContact CE1-CG 4.19Å; F43-E265 WeakPolarHBondContact CE1-OE2 3.43Å; F43-E265 HydrophobicContact CE2-CG 4.11Å; F43-E265 HydrophobicContact CZ-CB 3.71Å; F43-E265 VanDerWaalsContact CZ-CD 3.47Å; F43-E265 HydrophobicContact CZ-CG 3.45Å; F43-E265 VanDerWaalsContact CZ-CG 3.45Å; F43-E265 WeakPolarHBondContact CZ-OE2 3.2Å; M261-E265 HydrophobicContact CE-CG 4.01Å; M261-E265 VanDerWaalsContact CE-OE1 3.23Å; M261-E265 WeakPolarHBondContact CE-OE1 3.49Å; M261-E265 WeakPolarHBondContact O-CG 3.43Å; M261-E265 PolarHBondContact O-N 3.21Å; T262-E265 PolarHBondContact O-N 2.9Å; Q263-E265 VanDerWaalsContact C-N 3.26Å; Q263-E265 PolarHBondContact O-N 3.27Å; E265-E267 VanDerWaalsContact C-N 3.3Å; E265-E267 PolarHBondContact O-N 2.97Å; E265-K268 PolarHBondContact O-N 3.3Å; E265-K268 IonicContact OE1-NZ 3.83Å; E265-K268 PolarHBondContact OE1-NZ 3.43Å; E265-K268 WeakPolarHBondContact OE2-CD 3.44Å; E265-K268 IonicContact OE2-NZ 2.67Å; E265-K268 PolarHBondContact OE2-NZ 3.22Å; E265-K268 VanDerWaalsContact OE2-NZ 3.09Å; E265-L269 WeakPolarHBondContact O-CG 3.18Å; E265-L269 PolarHBondContact O-N 3.35Å; E265-L445 HydrophobicContact CB-CD1 3.98Å; E265-L445 HydrophobicContact CB-CD2 4.18Å; E265-L445 HydrophobicContact CG-CD2 4.34Å
266L88.8Confident78.1Confident6 Ų674.2 Ų74.23%0.03138%0.38CS..Hα-helixtrans-63.2-35174.8-72.6171.4000112.6T262 Q263 L269 K270 F273 V390 L445 C448 I449 K452T262-L266 HydrophobicContact CG2-CD1 4.14Å; T262-L266 WeakPolarHBondContact O-CB 3.44Å; T262-L266 VanDerWaalsContact O-CG 3.27Å; T262-L266 WeakPolarHBondContact O-CG 3.48Å; T262-L266 PolarHBondContact O-N 2.94Å; Q263-L266 PolarHBondContact O-N 2.89Å; L266-L269 PolarHBondContact O-N 2.92Å; L266-K270 PolarHBondContact O-N 3.27Å; L266-F273 HydrophobicContact CD2-CE2 4.35Å; L266-F273 HydrophobicContact CD2-CZ 4.2Å; L266-V390 HydrophobicContact CD1-CG1 4.33Å; L266-L445 HydrophobicContact CD2-CD1 4.4Å; L266-L445 HydrophobicContact CG-CD1 4.25Å; L266-C448 HydrophobicContact CD1-CB 3.93Å; L266-C448 HydrophobicContact CD2-CB 4.1Å; L266-C448 HydrophobicContact CG-CB 4.5Å; L266-I449 HydrophobicContact CD2-CG1 3.72Å; L266-K452 HydrophobicContact CD2-CD 4.34Å
267E88.9Confident81.1Confident96 Ų9672.3 Ų72.345%0.44936%0.361SS..Hα-helixtrans-67-37.9175.3-77.2-58.8140.200112.1Q263 E265 L269 K270Q263-E267 PolarHBondContact O-N 3.01Å; E265-E267 VanDerWaalsContact C-N 3.3Å; E265-E267 PolarHBondContact O-N 2.97Å; E267-L269 PolarHBondContact O-N 3.2Å; E267-K270 WeakPolarHBondContact O-CB 3.2Å; E267-K270 PolarHBondContact O-N 3.11Å; E267-K270 VanDerWaalsContact O-N 3.11Å
268K90.4Very high83.8Confident120 Ų12070.6 Ų70.652%0.52235%0.348SS..Hα-helixtrans-62.1-23.7173.4-67.5174.4-164.3166.10112.9Q264 E265Q264-K268 WeakPolarHBondContact O-CG 3.47Å; Q264-K268 PolarHBondContact O-N 2.86Å; E265-K268 PolarHBondContact O-N 3.3Å; E265-K268 IonicContact OE1-NZ 3.83Å; E265-K268 PolarHBondContact OE1-NZ 3.43Å; E265-K268 WeakPolarHBondContact OE2-CD 3.44Å; E265-K268 IonicContact OE2-NZ 2.67Å; E265-K268 PolarHBondContact OE2-NZ 3.22Å; E265-K268 VanDerWaalsContact OE2-NZ 3.09Å
269L92.1Very high85.7Confident10 Ų1063.9 Ų63.95%0.05232%0.32CS..THydrogen-bonded Turntrans-95.60.1179.8-60.1173.9000113.2W42 W44 E265 L266 E267 D271 H272 F273 L358 I449W42-L269 HydrophobicContact CE3-CD2 4.43Å; W42-L269 HydrophobicContact CZ3-CD2 4.18Å; W44-L269 HydrophobicContact CH2-CD1 3.47Å; W44-L269 VanDerWaalsContact CH2-CD1 3.47Å; W44-L269 HydrophobicContact CH2-CD2 3.8Å; W44-L269 HydrophobicContact CH2-CG 4.26Å; W44-L269 HydrophobicContact CZ2-CD1 4.38Å; W44-L269 HydrophobicContact CZ3-CD1 3.69Å; W44-L269 HydrophobicContact CZ3-CD2 4.14Å; W44-L269 HydrophobicContact CZ3-CG 4.43Å; E265-L269 WeakPolarHBondContact O-CG 3.18Å; E265-L269 PolarHBondContact O-N 3.35Å; L266-L269 PolarHBondContact O-N 2.92Å; E267-L269 PolarHBondContact O-N 3.2Å; L269-D271 VanDerWaalsContact C-N 3.3Å; L269-D271 PolarHBondContact O-N 3.21Å; L269-H272 WeakPolarHBondContact O-CB 3.32Å; L269-H272 PolarHBondContact O-N 3.5Å; L269-F273 HydrophobicContact CB-CD2 4.46Å; L269-F273 HydrophobicContact CB-CE2 3.69Å; L269-F273 HydrophobicContact CB-CZ 3.86Å; L269-F273 HydrophobicContact CD1-CZ 4.43Å; L269-F273 WeakPolarHBondContact O-CD2 3.38Å; L269-F273 PolarHBondContact O-N 3.24Å; L269-L358 HydrophobicContact CB-CD2 4.46Å; L269-L358 HydrophobicContact CD1-CD1 4.23Å; L269-L358 HydrophobicContact CD2-CD1 3.98Å; L269-I449 HydrophobicContact CD1-CD1 3.64Å; L269-I449 HydrophobicContact CD1-CG1 3.8Å; L269-I449 HydrophobicContact CD1-CG2 4.43Å
270K91.5Very high87.7Confident102 Ų10261.8 Ų61.844%0.44331%0.313SS..Hα-helixtrans-53.4-43.8-173.5-175.5174.9177.5177.20113.8L266 E267 H272 F273 Q274L266-K270 PolarHBondContact O-N 3.27Å; E267-K270 WeakPolarHBondContact O-CB 3.2Å; E267-K270 PolarHBondContact O-N 3.11Å; E267-K270 VanDerWaalsContact O-N 3.11Å; K270-H272 PolarHBondContact O-N 2.9Å; K270-F273 PolarHBondContact O-N 3.39Å; K270-Q274 PolarHBondContact O-N 3.5Å
271D91.8Very high89.3Confident109 Ų10959.3 Ų59.358%0.58331%0.307SS*.Hα-helixtrans-60.7-35.9-178.8-64.1-20.1000111.7L269 Q274 Q275L269-D271 VanDerWaalsContact C-N 3.3Å; L269-D271 PolarHBondContact O-N 3.21Å; D271-Q274 WeakPolarHBondContact O-CB 3.32Å; D271-Q274 PolarHBondContact O-N 3.17Å; D271-Q275 WeakPolarHBondContact O-CG 3.3Å; D271-Q275 PolarHBondContact O-N 3.27Å
272H93.4Very high90.1Very high41 Ų4159 Ų5919%0.1931%0.314CS..Hα-helixtrans-67.5-44177.8-60.183.4000111.6W42 L269 K270 Q274 Q275 L276 T354 A355 L358W42-H272 AromaticContact CH2-NE2 3.64Å; L269-H272 WeakPolarHBondContact O-CB 3.32Å; L269-H272 PolarHBondContact O-N 3.5Å; K270-H272 PolarHBondContact O-N 2.9Å; H272-Q274 VanDerWaalsContact C-N 3.26Å; H272-Q274 PolarHBondContact O-N 3.42Å; H272-Q275 WeakPolarHBondContact O-CB 3.42Å; H272-Q275 PolarHBondContact O-N 3.15Å; H272-L276 PolarHBondContact O-N 3.27Å; H272-T354 WeakPolarHBondContact NE2-CG2 3.44Å; H272-A355 HydrophobicContact CB-CB 4.15Å; H272-A355 WeakPolarHBondContact O-CB 3.48Å; H272-L358 HydrophobicContact CB-CD2 3.58Å
273F93.6Very high90.7Very high6 Ų659.3 Ų59.33%0.02632%0.316CS..Hα-helixtrans-61.8-39.3174.4-55.1-49.2000111L266 L269 K270 L276 S277 L358 I449 K452 S453L266-F273 HydrophobicContact CD2-CE2 4.35Å; L266-F273 HydrophobicContact CD2-CZ 4.2Å; L269-F273 HydrophobicContact CB-CD2 4.46Å; L269-F273 HydrophobicContact CB-CE2 3.69Å; L269-F273 HydrophobicContact CB-CZ 3.86Å; L269-F273 HydrophobicContact CD1-CZ 4.43Å; L269-F273 WeakPolarHBondContact O-CD2 3.38Å; L269-F273 PolarHBondContact O-N 3.24Å; K270-F273 PolarHBondContact O-N 3.39Å; F273-L276 PolarHBondContact O-N 3.42Å; F273-S277 PolarHBondContact O-N 3.15Å; F273-L358 HydrophobicContact CD1-CD2 4.42Å; F273-L358 HydrophobicContact CE1-CD2 3.92Å; F273-L358 HydrophobicContact CZ-CD2 4.41Å; F273-I449 HydrophobicContact CE1-CG2 4.32Å; F273-I449 HydrophobicContact CZ-CG2 4.34Å; F273-K452 HydrophobicContact CD1-CG 4.39Å; F273-K452 HydrophobicContact CD2-CD 4.08Å; F273-K452 HydrophobicContact CD2-CG 4.17Å; F273-K452 HydrophobicContact CE1-CB 4.21Å; F273-K452 HydrophobicContact CE1-CG 4.42Å; F273-K452 HydrophobicContact CE2-CD 3.85Å; F273-K452 HydrophobicContact CE2-CG 4.2Å; F273-K452 HydrophobicContact CG-CG 4.28Å; F273-K452 HydrophobicContact CZ-CB 4.25Å; F273-K452 HydrophobicContact CZ-CD 4.27Å; F273-K452 HydrophobicContact CZ-CG 4.32Å; F273-S453 WeakPolarHBondContact CE1-OG 3.29Å
274Q93.1Very high91.3Very high100 Ų10057.7 Ų57.747%0.46731%0.308SS..Hα-helixtrans-62.6-44175.8-172.6172.8-14.800111.5K270 D271 H272 L276 S277 T278K270-Q274 PolarHBondContact O-N 3.5Å; D271-Q274 WeakPolarHBondContact O-CB 3.32Å; D271-Q274 PolarHBondContact O-N 3.17Å; H272-Q274 VanDerWaalsContact C-N 3.26Å; H272-Q274 PolarHBondContact O-N 3.42Å; Q274-L276 VanDerWaalsContact C-N 3.29Å; Q274-L276 PolarHBondContact O-N 3.48Å; Q274-S277 WeakPolarHBondContact CA-OG 3.31Å; Q274-S277 PolarHBondContact O-N 2.93Å; Q274-S277 VanDerWaalsContact O-N 3.09Å; Q274-S277 PolarHBondContact O-OG 3.48Å; Q274-T278 HydrophobicContact CG-CG2 4.15Å; Q274-T278 WeakPolarHBondContact O-CG2 3.28Å; Q274-T278 PolarHBondContact O-N 2.89Å; Q274-T278 PolarHBondContact O-OG1 3.05Å; Q274-T278 VanDerWaalsContact O-OG1 3.14Å
275Q92.8Very high91.6Very high67 Ų6754.5 Ų54.531%0.31330%0.298SS..Hα-helixtrans-52.9-47.3175.1-67.8-53.2-53.600111.5D271 H272 S277 T278 P351 A355D271-Q275 WeakPolarHBondContact O-CG 3.3Å; D271-Q275 PolarHBondContact O-N 3.27Å; H272-Q275 WeakPolarHBondContact O-CB 3.42Å; H272-Q275 PolarHBondContact O-N 3.15Å; Q275-S277 PolarHBondContact O-N 3.37Å; Q275-T278 PolarHBondContact O-N 2.78Å; Q275-T278 PolarHBondContact O-OG1 3.08Å; Q275-P351 HydrophobicContact CG-CB 3.96Å; Q275-A355 HydrophobicContact CB-CB 4.06Å
276L93.1Very high91.9Very high0 Ų055.7 Ų55.70%031%0.308CS..Hα-helixtrans-61.9-44.4177.7-60.7172.4000111.8H272 F273 Q274 T278 L279 R284 A355 L356 V359 L457H272-L276 PolarHBondContact O-N 3.27Å; F273-L276 PolarHBondContact O-N 3.42Å; Q274-L276 VanDerWaalsContact C-N 3.29Å; Q274-L276 PolarHBondContact O-N 3.48Å; L276-T278 VanDerWaalsContact C-N 3.29Å; L276-T278 PolarHBondContact O-N 3.39Å; L276-L279 WeakPolarHBondContact O-CB 3.42Å; L276-L279 PolarHBondContact O-N 2.77Å; L276-R284 WeakPolarHBondContact O-CD 3.44Å; L276-R284 WeakPolarHBondContact O-CG 3.33Å; L276-A355 HydrophobicContact CD2-CB 3.83Å; L276-A355 HydrophobicContact CG-CB 3.93Å; L276-L356 HydrophobicContact CD2-CD2 4.26Å; L276-L356 HydrophobicContact CD2-CG 4.32Å; L276-V359 HydrophobicContact CD1-CG2 3.5Å; L276-V359 VanDerWaalsContact CD1-CG2 3.5Å; L276-V359 HydrophobicContact CD2-CG2 4.37Å; L276-L457 HydrophobicContact CB-CD2 4.09Å; L276-L457 HydrophobicContact CB-CG 4.42Å; L276-L457 HydrophobicContact CD2-CD2 4.12Å
277S91.8Very high92.2Very high40 Ų4055.4 Ų55.428%0.2831%0.306SS..Hα-helixtrans-67.5-27.5-178.572.60000113.6F273 Q274 Q275 R284 S456F273-S277 PolarHBondContact O-N 3.15Å; Q274-S277 WeakPolarHBondContact CA-OG 3.31Å; Q274-S277 PolarHBondContact O-N 2.93Å; Q274-S277 VanDerWaalsContact O-N 3.09Å; Q274-S277 PolarHBondContact O-OG 3.48Å; Q275-S277 PolarHBondContact O-N 3.37Å; S277-R284 PolarHBondContact O-NH1 3.13Å; S277-S456 WeakPolarHBondContact CA-O 3.41Å
278T92.1Very high92.5Very high90 Ų9051.5 Ų51.555%0.55229%0.288SS*.Hα-helixtrans-84.1-8.8-179.154.80000114.4Q274 Q275 L276Q274-T278 HydrophobicContact CG-CG2 4.15Å; Q274-T278 WeakPolarHBondContact O-CG2 3.28Å; Q274-T278 PolarHBondContact O-N 2.89Å; Q274-T278 PolarHBondContact O-OG1 3.05Å; Q274-T278 VanDerWaalsContact O-OG1 3.14Å; Q275-T278 PolarHBondContact O-N 2.78Å; Q275-T278 PolarHBondContact O-OG1 3.08Å; L276-T278 VanDerWaalsContact C-N 3.29Å; L276-T278 PolarHBondContact O-N 3.39Å
279L91.5Very high92.7Very high22 Ų2252 Ų5212%0.11529%0.287CS..SBendtrans-62.3154.2175.1-68.2174.3000111L276 T283 R284 L287 V352L276-L279 WeakPolarHBondContact O-CB 3.42Å; L276-L279 PolarHBondContact O-N 2.77Å; L279-T283 HydrophobicContact CD1-CG2 4.45Å; L279-R284 HydrophobicContact CB-CG 3.54Å; L279-R284 VanDerWaalsContact O-CD 3.27Å; L279-R284 WeakPolarHBondContact O-CD 3.45Å; L279-R284 PolarHBondContact O-NE 3.35Å; L279-R284 VanDerWaalsContact O-NE 3.17Å; L279-L287 HydrophobicContact CD1-CD1 3.69Å; L279-V352 HydrophobicContact CD1-CG1 4.22Å; L279-V352 HydrophobicContact CD2-CG1 4.06Å; L279-V352 HydrophobicContact CD2-CG2 3.87Å
280P92.7Very high92.8Very high77 Ų7752.2 Ų52.250%0.529%0.288SS..  trans-53.8142.8174.6-24.633.6000111.9S282 T283 R284P280-S282 VanDerWaalsContact C-N 3.27Å; P280-S282 PolarHBondContact O-N 2.97Å; P280-T283 WeakPolarHBondContact O-CA 3.19Å; P280-T283 WeakPolarHBondContact O-CB 3.43Å; P280-T283 PolarHBondContact O-N 3.17Å; P280-R284 PolarHBondContact O-N 3.45Å
281A92.1Very high93Very high50 Ų5047.4 Ų47.441%0.41327%0.267SS..Hα-helixtrans-53.9-43.1-177.100000112.7T283 R284 S285A281-T283 PolarHBondContact O-N 3.05Å; A281-R284 PolarHBondContact O-N 3.46Å; A281-S285 PolarHBondContact O-N 3.08Å; A281-S285 PolarHBondContact O-OG 3.02Å; A281-S285 VanDerWaalsContact O-OG 3.1Å
282S90.8Very high93.1Very high93 Ų9343.3 Ų43.365%0.6525%0.246SC*.Hα-helixtrans-61.1-42175.352.40000113P280 S286P280-S282 VanDerWaalsContact C-N 3.27Å; P280-S282 PolarHBondContact O-N 2.97Å; S282-S286 VanDerWaalsContact O-CB 3.3Å; S282-S286 WeakPolarHBondContact O-CB 3.43Å; S282-S286 PolarHBondContact O-N 3.37Å
283T91.8Very high93.1Very high33 Ų3343.6 Ų43.620%0.20225%0.247CC..Hα-helixtrans-64.5-44.4176.4-540000111.1L279 P280 A281 S286 L287 V338L279-T283 HydrophobicContact CD1-CG2 4.45Å; P280-T283 WeakPolarHBondContact O-CA 3.19Å; P280-T283 WeakPolarHBondContact O-CB 3.43Å; P280-T283 PolarHBondContact O-N 3.17Å; A281-T283 PolarHBondContact O-N 3.05Å; T283-S286 PolarHBondContact O-N 3.46Å; T283-L287 HydrophobicContact CG2-CD1 4.11Å; T283-L287 HydrophobicContact CG2-CG 4.45Å; T283-L287 WeakPolarHBondContact O-CB 3.16Å; T283-L287 WeakPolarHBondContact O-CG 3.26Å; T283-L287 PolarHBondContact O-N 2.92Å; T283-V338 HydrophobicContact CG2-CB 4.46Å; T283-V338 HydrophobicContact CG2-CG1 3.44Å; T283-V338 VanDerWaalsContact CG2-CG1 3.44Å; T283-V338 HydrophobicContact CG2-CG2 4.12Å
284R92.9Very high93Very high23 Ų2343.3 Ų43.39%0.08725%0.246CC..Hα-helixtrans-63.3-48.6178.4-67.1-177.5-55.6160.719.7111.9L276 S277 L279 P280 A281 S286 L287 L288 L457 C459 G460L276-R284 WeakPolarHBondContact O-CD 3.44Å; L276-R284 WeakPolarHBondContact O-CG 3.33Å; S277-R284 PolarHBondContact O-NH1 3.13Å; L279-R284 HydrophobicContact CB-CG 3.54Å; L279-R284 VanDerWaalsContact O-CD 3.27Å; L279-R284 WeakPolarHBondContact O-CD 3.45Å; L279-R284 PolarHBondContact O-NE 3.35Å; L279-R284 VanDerWaalsContact O-NE 3.17Å; P280-R284 PolarHBondContact O-N 3.45Å; A281-R284 PolarHBondContact O-N 3.46Å; R284-S286 VanDerWaalsContact C-N 3.31Å; R284-S286 PolarHBondContact O-N 2.88Å; R284-L287 PolarHBondContact O-N 3.25Å; R284-L288 WeakPolarHBondContact O-CB 3.15Å; R284-L288 PolarHBondContact O-N 2.91Å; R284-L457 HydrophobicContact CB-CD2 4.49Å; R284-L457 WeakPolarHBondContact CB-O 3.47Å; R284-L457 HydrophobicContact CG-CD2 4.43Å; R284-C459 PolarHBondContact NH1-O 3.38Å; R284-C459 PolarHBondContact NH2-O 3.42Å; R284-G460 PolarHBondContact NH2-O 3.3Å
285S91.6Very high93Very high47 Ų4738.5 Ų38.533%0.32922%0.224SC..Hα-helixtrans-60.6-39.7175.5-56.80000112.3A281 R289 C461A281-S285 PolarHBondContact O-N 3.08Å; A281-S285 PolarHBondContact O-OG 3.02Å; A281-S285 VanDerWaalsContact O-OG 3.1Å; S285-R289 WeakPolarHBondContact O-CB 3.34Å; S285-R289 PolarHBondContact O-N 3.05Å; S285-C461 WeakPolarHBondContact OG-CB 3.04Å; S285-C461 PolarHBondContact OG-SG 3.14Å
286S93Very high92.8Very high37 Ų3740.8 Ų40.826%0.25924%0.235SC..Hα-helixtrans-64.4-49176.4-166.40000111.8S282 T283 R284 R289 H290S282-S286 VanDerWaalsContact O-CB 3.3Å; S282-S286 WeakPolarHBondContact O-CB 3.43Å; S282-S286 PolarHBondContact O-N 3.37Å; T283-S286 PolarHBondContact O-N 3.46Å; R284-S286 VanDerWaalsContact C-N 3.31Å; R284-S286 PolarHBondContact O-N 2.88Å; S286-R289 PolarHBondContact O-N 3.37Å; S286-H290 PolarHBondContact O-CD2 3.05Å; S286-H290 PolarHBondContact O-N 3Å; S286-H290 PolarHBondContact OG-CD2 3.3Å
287L94.4Very high92.3Very high0 Ų044.5 Ų44.50%025%0.252CS..Hα-helixtrans-60-47.4177.4-76.3172.8000111.7L279 T283 R284 R289 H290 I291 V335 V338 L356 L457L279-L287 HydrophobicContact CD1-CD1 3.69Å; T283-L287 HydrophobicContact CG2-CD1 4.11Å; T283-L287 HydrophobicContact CG2-CG 4.45Å; T283-L287 WeakPolarHBondContact O-CB 3.16Å; T283-L287 WeakPolarHBondContact O-CG 3.26Å; T283-L287 PolarHBondContact O-N 2.92Å; R284-L287 PolarHBondContact O-N 3.25Å; L287-R289 VanDerWaalsContact C-N 3.31Å; L287-R289 PolarHBondContact O-N 3.3Å; L287-H290 PolarHBondContact O-N 3.46Å; L287-I291 WeakPolarHBondContact O-CB 3.47Å; L287-I291 VanDerWaalsContact O-CG1 3.24Å; L287-I291 WeakPolarHBondContact O-CG1 3.36Å; L287-I291 PolarHBondContact O-N 2.96Å; L287-V335 HydrophobicContact CD2-CG1 4.4Å; L287-V335 HydrophobicContact CD2-CG2 4.33Å; L287-V338 HydrophobicContact CD1-CG1 3.99Å; L287-V338 HydrophobicContact CD2-CB 4.08Å; L287-V338 HydrophobicContact CD2-CG1 4.09Å; L287-V338 HydrophobicContact CD2-CG2 4.05Å; L287-V338 HydrophobicContact CG-CG1 4.21Å; L287-V338 HydrophobicContact CG-CG2 4.33Å; L287-L356 HydrophobicContact CD1-CD1 4.32Å; L287-L356 HydrophobicContact CD1-CD2 4.19Å; L287-L356 HydrophobicContact CD2-CD1 4.1Å; L287-L356 HydrophobicContact CD2-CD2 4.16Å; L287-L457 HydrophobicContact CB-CD1 4.45Å; L287-L457 HydrophobicContact CB-CD2 4.17Å; L287-L457 HydrophobicContact CD1-CD2 4.05Å
288L95.3Very high92Very high14 Ų1444.2 Ų44.27%0.07325%0.249CC..Hα-helixtrans-58.2-45.8178-178.861.6000110.9R284 T292 C378 L383 L454 L457 A458R284-L288 WeakPolarHBondContact O-CB 3.15Å; R284-L288 PolarHBondContact O-N 2.91Å; L288-T292 WeakPolarHBondContact O-CB 3.39Å; L288-T292 PolarHBondContact O-N 2.69Å; L288-T292 PolarHBondContact O-OG1 2.93Å; L288-C378 HydrophobicContact CD1-CB 4.5Å; L288-L383 HydrophobicContact CD1-CD1 4.14Å; L288-L383 HydrophobicContact CD2-CD1 4.24Å; L288-L454 HydrophobicContact CD1-CB 4.47Å; L288-L454 HydrophobicContact CD1-CD2 3.94Å; L288-L457 HydrophobicContact CB-CB 4.12Å; L288-L457 HydrophobicContact CD1-CB 4.37Å; L288-A458 HydrophobicContact CD2-CB 3.84Å
289R94.6Very high91.5Very high130 Ų13043 Ų4349%0.49125%0.248SC..Hα-helixtrans-61-50.3178.3-176.9-177.957.670.54111.7S285 S286 L287 T292 E293S285-R289 WeakPolarHBondContact O-CB 3.34Å; S285-R289 PolarHBondContact O-N 3.05Å; S286-R289 PolarHBondContact O-N 3.37Å; L287-R289 VanDerWaalsContact C-N 3.31Å; L287-R289 PolarHBondContact O-N 3.3Å; R289-T292 PolarHBondContact O-N 3.13Å; R289-E293 PolarHBondContact O-N 3.05Å
290H95.4Very high91.3Very high16 Ų1642 Ų427%0.07424%0.243CC..Hα-helixtrans-66-41.6-178.5-73.7-62000112.6S286 L287 E293 L294 S331 A334 V335S286-H290 PolarHBondContact O-CD2 3.05Å; S286-H290 PolarHBondContact O-N 3Å; S286-H290 PolarHBondContact OG-CD2 3.3Å; L287-H290 PolarHBondContact O-N 3.46Å; H290-E293 PolarHBondContact O-N 2.69Å; H290-L294 VanDerWaalsContact O-CG 3.3Å; H290-L294 WeakPolarHBondContact O-CG 3.46Å; H290-L294 PolarHBondContact O-N 3.49Å; H290-L294 VanDerWaalsContact O-N 3.12Å; H290-S331 WeakPolarHBondContact ND1-CA 3.45Å; H290-S331 WeakPolarHBondContact ND1-CB 3.39Å; H290-S331 PolarHBondContact ND1-OG 2.89Å; H290-A334 VanDerWaalsContact CE1-CB 3.42Å; H290-A334 WeakPolarHBondContact CE1-CB 3.44Å; H290-A334 WeakPolarHBondContact NE2-CB 3.42Å; H290-V335 HydrophobicContact CB-CG2 3.91Å
291I95.4Very high91.3Very high0 Ų038.3 Ų38.30%022%0.219CC..Hα-helixtrans-63.7-44.2175.7-67.8168.1000110.1L287 E293 L294 M295 L356 V359 L363 L454 L457L287-I291 WeakPolarHBondContact O-CB 3.47Å; L287-I291 VanDerWaalsContact O-CG1 3.24Å; L287-I291 WeakPolarHBondContact O-CG1 3.36Å; L287-I291 PolarHBondContact O-N 2.96Å; I291-E293 VanDerWaalsContact C-N 3.32Å; I291-E293 PolarHBondContact O-N 3.32Å; I291-L294 PolarHBondContact O-N 3.21Å; I291-L294 VanDerWaalsContact O-N 3.16Å; I291-M295 HydrophobicContact CG2-CG 4.36Å; I291-M295 HydrophobicContact CG2-SD 3.99Å; I291-M295 VanDerWaalsContact O-CG 3.24Å; I291-M295 WeakPolarHBondContact O-CG 3.4Å; I291-M295 PolarHBondContact O-N 3.44Å; I291-L356 HydrophobicContact CD1-CD2 4.1Å; I291-V359 HydrophobicContact CD1-CG1 4.49Å; I291-L363 HydrophobicContact CG2-CD1 3.48Å; I291-L363 VanDerWaalsContact CG2-CD1 3.48Å; I291-L454 HydrophobicContact CG2-CD2 4.17Å; I291-L457 HydrophobicContact CD1-CD1 3.92Å
292T93.8Very high91.1Very high24 Ų2438.1 Ų38.115%0.14721%0.214CC..Hα-helixtrans-61.7-38.7177.9-590000112L288 R289 M295 S375 C378L288-T292 WeakPolarHBondContact O-CB 3.39Å; L288-T292 PolarHBondContact O-N 2.69Å; L288-T292 PolarHBondContact O-OG1 2.93Å; R289-T292 PolarHBondContact O-N 3.13Å; T292-M295 PolarHBondContact O-N 3.03Å; T292-S375 WeakPolarHBondContact CG2-O 3.39Å; T292-C378 HydrophobicContact CG2-CB 3.73Å; T292-C378 WeakPolarHBondContact OG1-CB 3.19Å
293E92.5Very high90.9Very high46 Ų4634.8 Ų34.822%0.21519%0.19CC..Hα-helixtrans-62.4-43.6174.3-172.1-178.1158.800111.7R289 H290 I291 M295 Q296 S327 S331R289-E293 PolarHBondContact O-N 3.05Å; H290-E293 PolarHBondContact O-N 2.69Å; I291-E293 VanDerWaalsContact C-N 3.32Å; I291-E293 PolarHBondContact O-N 3.32Å; E293-M295 VanDerWaalsContact C-N 3.32Å; E293-M295 PolarHBondContact O-N 3.24Å; E293-Q296 WeakPolarHBondContact O-CB 3.23Å; E293-Q296 PolarHBondContact O-N 3.34Å; E293-S327 WeakPolarHBondContact OE1-CB 3.45Å; E293-S327 PolarHBondContact OE1-OG 3.42Å; E293-S331 PolarHBondContact OE2-OG 2.86Å
294L92.6Very high90.8Very high0 Ų033.2 Ų33.20%018%0.18CC..Hα-helixtrans-67.5-31.9178.6-64170000112.4H290 I291 Q296 E297 A300 I301 L304 Q328 I332H290-L294 VanDerWaalsContact O-CG 3.3Å; H290-L294 WeakPolarHBondContact O-CG 3.46Å; H290-L294 PolarHBondContact O-N 3.49Å; H290-L294 VanDerWaalsContact O-N 3.12Å; I291-L294 PolarHBondContact O-N 3.21Å; I291-L294 VanDerWaalsContact O-N 3.16Å; L294-Q296 PolarHBondContact O-N 3.43Å; L294-E297 PolarHBondContact O-N 3.46Å; L294-A300 HydrophobicContact CB-CB 4.33Å; L294-A300 HydrophobicContact CD2-CB 3.82Å; L294-I301 HydrophobicContact CB-CD1 3.66Å; L294-I301 HydrophobicContact CB-CG1 4.26Å; L294-L304 HydrophobicContact CD1-CD2 3.75Å; L294-Q328 HydrophobicContact CD2-CB 3.92Å; L294-Q328 HydrophobicContact CD2-CG 4.26Å; L294-I332 HydrophobicContact CD1-CG1 3.93Å; L294-I332 HydrophobicContact CD2-CD1 4.31Å; L294-I332 HydrophobicContact CD2-CG1 3.85Å
295M92.8Very high90.7Very high0 Ų032.1 Ų32.10%018%0.176CC..Hα-helixtrans-64.1-17.5178.2-71.3166.762.700114I291 T292 E293 E297 I301 L363 L371 L374 L454I291-M295 HydrophobicContact CG2-CG 4.36Å; I291-M295 HydrophobicContact CG2-SD 3.99Å; I291-M295 VanDerWaalsContact O-CG 3.24Å; I291-M295 WeakPolarHBondContact O-CG 3.4Å; I291-M295 PolarHBondContact O-N 3.44Å; T292-M295 PolarHBondContact O-N 3.03Å; E293-M295 VanDerWaalsContact C-N 3.32Å; E293-M295 PolarHBondContact O-N 3.24Å; M295-E297 PolarHBondContact O-N 2.99Å; M295-I301 HydrophobicContact CG-CD1 3.95Å; M295-I301 HydrophobicContact CG-CG1 4.25Å; M295-L363 HydrophobicContact CE-CD2 3.9Å; M295-L363 HydrophobicContact CG-CD1 4.05Å; M295-L363 HydrophobicContact CG-CD2 4.43Å; M295-L363 HydrophobicContact SD-CD1 3.93Å; M295-L363 HydrophobicContact SD-CD2 4Å; M295-L371 HydrophobicContact CE-CD2 4.37Å; M295-L371 HydrophobicContact CG-CD2 4.22Å; M295-L371 CarbonylContact O-C 3.42Å; M295-L371 VanDerWaalsContact O-C 3.27Å; M295-L374 HydrophobicContact CE-CB 3.84Å; M295-L374 HydrophobicContact CE-CD2 3.76Å; M295-L374 HydrophobicContact CE-CG 3.66Å; M295-L454 HydrophobicContact CE-CD1 4.17Å; M295-L454 HydrophobicContact SD-CD1 4.37Å; M295-L454 HydrophobicContact SD-CD2 4.32Å
296Q88.1Confident90.3Very high115 Ų11533.1 Ų33.154%0.53718%0.178SC..THydrogen-bonded Turntrans-64.4-22.8175.8-62.8-17824.800112.6E293 L294E293-Q296 WeakPolarHBondContact O-CB 3.23Å; E293-Q296 PolarHBondContact O-N 3.34Å; L294-Q296 PolarHBondContact O-N 3.43Å
297E83.1Confident89.9Confident78 Ų7831.8 Ų31.836%0.36417%0.167SC..SBendtrans-134.7104-176.6-66.2-82.3-165.200108.6L294 M295 A299 A300 K325 Q328L294-E297 PolarHBondContact O-N 3.46Å; M295-E297 PolarHBondContact O-N 2.99Å; E297-A299 PolarHBondContact O-N 3.28Å; E297-A300 HydrophobicContact CB-CB 4.34Å; E297-A300 WeakPolarHBondContact O-CB 3.45Å; E297-A300 PolarHBondContact O-N 2.83Å; E297-K325 IonicContact OE1-NZ 2.85Å; E297-K325 PolarHBondContact OE1-NZ 2.99Å; E297-Q328 VanDerWaalsContact CB-NE2 3.29Å; E297-Q328 VanDerWaalsContact CG-NE2 3.33Å
298P84.8Confident89.5Confident34 Ų3431.8 Ų31.822%0.22117%0.168CC..Hα-helixtrans-51.8-32.6-175.8-30.336000114.4A300 I301 C302 D368 L371P298-A300 VanDerWaalsContact C-N 3.28Å; P298-A300 PolarHBondContact O-N 2.79Å; P298-I301 PolarHBondContact O-N 2.67Å; P298-C302 PolarHBondContact O-N 3.25Å; P298-C302 VanDerWaalsContact O-N 3.07Å; P298-D368 HydrophobicContact CB-CB 4.21Å; P298-D368 HydrophobicContact CG-CB 3.99Å; P298-D368 VanDerWaalsContact CG-O 3.29Å; P298-D368 WeakPolarHBondContact CG-O 3.49Å; P298-L371 HydrophobicContact CB-CD1 4.04Å; P298-L371 HydrophobicContact CG-CB 4.47Å; P298-L371 HydrophobicContact CG-CD1 4.26Å
299A82.8Confident88.9Confident65 Ų6532.5 Ų32.554%0.53717%0.171SC..Hα-helixtrans-60.4-33.6175.300000113.3E297 C302 T303E297-A299 PolarHBondContact O-N 3.28Å; A299-C302 PolarHBondContact O-N 2.97Å; A299-T303 PolarHBondContact O-N 2.87Å; A299-T303 PolarHBondContact O-OG1 3.28Å; A299-T303 VanDerWaalsContact O-OG1 3.11Å
300A87.6Confident88.1Confident0 Ų030 Ų300%016%0.162CC..Hα-helixtrans-72-39.5179.600000112.2L294 E297 P298 T303 L304 L324 Q328L294-A300 HydrophobicContact CB-CB 4.33Å; L294-A300 HydrophobicContact CD2-CB 3.82Å; E297-A300 HydrophobicContact CB-CB 4.34Å; E297-A300 WeakPolarHBondContact O-CB 3.45Å; E297-A300 PolarHBondContact O-N 2.83Å; P298-A300 VanDerWaalsContact C-N 3.28Å; P298-A300 PolarHBondContact O-N 2.79Å; A300-T303 PolarHBondContact O-N 3.35Å; A300-L304 PolarHBondContact O-N 3.29Å; A300-L324 HydrophobicContact CB-CD2 3.98Å; A300-Q328 HydrophobicContact CB-CG 4.28Å
301I91.8Very high87.4Confident0 Ų031.5 Ų31.50%017%0.17CC..Hα-helixtrans-62.9-42.4171.5-67.9-65000110.9L294 M295 P298 T303 L304 Q305 V360 L363 E364L294-I301 HydrophobicContact CB-CD1 3.66Å; L294-I301 HydrophobicContact CB-CG1 4.26Å; M295-I301 HydrophobicContact CG-CD1 3.95Å; M295-I301 HydrophobicContact CG-CG1 4.25Å; P298-I301 PolarHBondContact O-N 2.67Å; I301-T303 VanDerWaalsContact C-N 3.34Å; I301-T303 PolarHBondContact O-N 3.09Å; I301-L304 PolarHBondContact O-N 3.25Å; I301-Q305 WeakPolarHBondContact O-CB 3.46Å; I301-Q305 PolarHBondContact O-N 3.38Å; I301-V360 HydrophobicContact CG2-CG1 4.36Å; I301-L363 HydrophobicContact CD1-CD1 4.32Å; I301-L363 HydrophobicContact CG2-CB 4.02Å; I301-E364 HydrophobicContact CG2-CB 3.93Å
302C87.1Confident86.5Confident45 Ų4533.3 Ų33.330%0.30418%0.182SC..Hα-helixtrans-58.9-44.3174.7-1790000111.9P298 A299 L304 Q305 N306P298-C302 PolarHBondContact O-N 3.25Å; P298-C302 VanDerWaalsContact O-N 3.07Å; A299-C302 PolarHBondContact O-N 2.97Å; C302-L304 PolarHBondContact O-N 2.99Å; C302-Q305 PolarHBondContact O-N 3.38Å; C302-N306 WeakPolarHBondContact O-CB 3.28Å; C302-N306 VanDerWaalsContact O-CG 3.22Å; C302-N306 PolarHBondContact O-N 3.06Å; C302-N306 PolarHBondContact O-ND2 3.17Å
303T86.6Confident85.3Confident23 Ų2335.2 Ų35.214%0.14119%0.191CC..Hα-helixtrans-62.3-43.9176.2-61.30000112.2A299 A300 I301 N306 M307 L324 I332A299-T303 PolarHBondContact O-N 2.87Å; A299-T303 PolarHBondContact O-OG1 3.28Å; A299-T303 VanDerWaalsContact O-OG1 3.11Å; A300-T303 PolarHBondContact O-N 3.35Å; I301-T303 VanDerWaalsContact C-N 3.34Å; I301-T303 PolarHBondContact O-N 3.09Å; T303-N306 PolarHBondContact O-N 2.82Å; T303-M307 HydrophobicContact CG2-CE 3.48Å; T303-M307 VanDerWaalsContact CG2-CE 3.48Å; T303-M307 WeakPolarHBondContact O-CG 3.41Å; T303-M307 PolarHBondContact O-N 2.87Å; T303-M307 VanDerWaalsContact O-N 3.11Å; T303-L324 HydrophobicContact CG2-CD1 3.77Å; T303-I332 HydrophobicContact CG2-CD1 4.22Å
304L90.7Very high84.2Confident0 Ų036.6 Ų36.60%022%0.217CC..Hα-helixtrans-60.7-45.8174.618060.9000111.6L294 A300 I301 C302 N306 M307 L308 I332 V335 F336 V360L294-L304 HydrophobicContact CD1-CD2 3.75Å; A300-L304 PolarHBondContact O-N 3.29Å; I301-L304 PolarHBondContact O-N 3.25Å; C302-L304 PolarHBondContact O-N 2.99Å; L304-N306 VanDerWaalsContact C-N 3.34Å; L304-N306 PolarHBondContact O-N 3.48Å; L304-M307 PolarHBondContact O-N 3.44Å; L304-L308 HydrophobicContact CD1-CD1 4.44Å; L304-L308 HydrophobicContact CD1-CG 4.47Å; L304-L308 HydrophobicContact CG-CD1 4.2Å; L304-L308 WeakPolarHBondContact O-CG 3.27Å; L304-L308 PolarHBondContact O-N 3.07Å; L304-I332 HydrophobicContact CB-CG1 4.44Å; L304-I332 HydrophobicContact CD1-CG1 4.48Å; L304-I332 HydrophobicContact CD1-CG2 4.18Å; L304-V335 HydrophobicContact CD1-CG1 4.24Å; L304-F336 HydrophobicContact CD1-CE2 3.99Å; L304-F336 HydrophobicContact CD1-CZ 4.01Å; L304-V360 HydrophobicContact CB-CG1 4.29Å; L304-V360 HydrophobicContact CD2-CG1 4.11Å; L304-V360 HydrophobicContact CD2-CG2 3.61Å; L304-V360 HydrophobicContact CG-CG1 4.01Å; L304-V360 HydrophobicContact CG-CG2 4.13Å
305Q89.8Confident83.1Confident0 Ų041.5 Ų41.50%024%0.239CC..Hα-helixtrans-58.3-45.9176.9-179.954.541.900111.4I301 C302 M307 L308 D309 H357 V360 S361 E364I301-Q305 WeakPolarHBondContact O-CB 3.46Å; I301-Q305 PolarHBondContact O-N 3.38Å; C302-Q305 PolarHBondContact O-N 3.38Å; Q305-M307 VanDerWaalsContact C-N 3.28Å; Q305-M307 PolarHBondContact O-N 3.05Å; Q305-L308 PolarHBondContact O-N 3.33Å; Q305-D309 PolarHBondContact NE2-OD1 3.4Å; Q305-D309 PolarHBondContact NE2-OD2 2.84Å; Q305-D309 PolarHBondContact O-N 2.67Å; Q305-H357 PolarHBondContact NE2-NE2 3.2Å; Q305-V360 HydrophobicContact CB-CG1 3.81Å; Q305-S361 PolarHBondContact NE2-OG 3.4Å; Q305-S361 VanDerWaalsContact OE1-CA 3.27Å; Q305-S361 VanDerWaalsContact OE1-N 3.08Å; Q305-S361 PolarHBondContact OE1-OG 3.16Å; Q305-E364 HydrophobicContact CB-CB 4.36Å; Q305-E364 HydrophobicContact CB-CG 4.24Å; Q305-E364 HydrophobicContact CG-CB 4.39Å; Q305-E364 HydrophobicContact CG-CG 4.26Å
306N83.5Confident82.1Confident69 Ų6950.1 Ų50.137%0.36928%0.276SS..Hα-helixtrans-62.6-34.6179.4-70.7-27.4000112.4K48 C302 T303 L304 R310K48-N306 PolarHBondContact NZ-OD1 3.26Å; C302-N306 WeakPolarHBondContact O-CB 3.28Å; C302-N306 VanDerWaalsContact O-CG 3.22Å; C302-N306 PolarHBondContact O-N 3.06Å; C302-N306 PolarHBondContact O-ND2 3.17Å; T303-N306 PolarHBondContact O-N 2.82Å; L304-N306 VanDerWaalsContact C-N 3.34Å; L304-N306 PolarHBondContact O-N 3.48Å; N306-R310 WeakPolarHBondContact O-CG 3.42Å; N306-R310 PolarHBondContact O-N 3.14Å; N306-R310 VanDerWaalsContact O-N 3.09Å
307M85.1Confident81.2Confident8 Ų846.7 Ų46.74%0.03926%0.263CS..Hα-helixtrans-70.4-42.3174.6-68.6179.3-167.400112.1T303 L304 Q305 D309 R310 M311 L319 I332 F336T303-M307 HydrophobicContact CG2-CE 3.48Å; T303-M307 VanDerWaalsContact CG2-CE 3.48Å; T303-M307 WeakPolarHBondContact O-CG 3.41Å; T303-M307 PolarHBondContact O-N 2.87Å; T303-M307 VanDerWaalsContact O-N 3.11Å; L304-M307 PolarHBondContact O-N 3.44Å; Q305-M307 VanDerWaalsContact C-N 3.28Å; Q305-M307 PolarHBondContact O-N 3.05Å; M307-D309 VanDerWaalsContact C-N 3.34Å; M307-D309 PolarHBondContact O-N 3.43Å; M307-R310 WeakPolarHBondContact O-CB 3.47Å; M307-R310 PolarHBondContact O-N 2.97Å; M307-M311 PolarHBondContact O-N 2.89Å; M307-M311 VanDerWaalsContact O-N 3.08Å; M307-L319 HydrophobicContact CE-CB 4.37Å; M307-L319 HydrophobicContact CE-CD2 3.51Å; M307-L319 HydrophobicContact CE-CG 3.74Å; M307-L319 HydrophobicContact SD-CD2 4.25Å; M307-L319 HydrophobicContact SD-CG 4.2Å; M307-I332 HydrophobicContact SD-CG2 3.72Å; M307-F336 HydrophobicContact CB-CE2 3.92Å; M307-F336 HydrophobicContact CB-CZ 3.51Å; M307-F336 HydrophobicContact CG-CE2 4.47Å; M307-F336 HydrophobicContact SD-CE2 3.72Å; M307-F336 HydrophobicContact SD-CZ 4.3Å
308L86.6Confident80.3Confident1 Ų144.8 Ų44.81%0.00526%0.259CS..Hα-helixtrans-63.5-40.7175.1-64.4168.3000111.3L304 Q305 R310 M311 C312 F336 L339 F353 V360L304-L308 HydrophobicContact CD1-CD1 4.44Å; L304-L308 HydrophobicContact CD1-CG 4.47Å; L304-L308 HydrophobicContact CG-CD1 4.2Å; L304-L308 WeakPolarHBondContact O-CG 3.27Å; L304-L308 PolarHBondContact O-N 3.07Å; Q305-L308 PolarHBondContact O-N 3.33Å; L308-R310 VanDerWaalsContact C-N 3.3Å; L308-R310 PolarHBondContact O-N 3.46Å; L308-M311 WeakPolarHBondContact O-CB 3.46Å; L308-M311 PolarHBondContact O-N 3.35Å; L308-M311 VanDerWaalsContact O-N 3.16Å; L308-C312 PolarHBondContact O-N 3Å; L308-C312 PolarHBondContact O-SG 3Å; L308-F336 HydrophobicContact CD2-CE1 3.78Å; L308-F336 HydrophobicContact CD2-CZ 4.21Å; L308-F336 HydrophobicContact CG-CE1 4.47Å; L308-F336 HydrophobicContact CG-CZ 4.43Å; L308-L339 HydrophobicContact CD2-CD1 3.83Å; L308-F353 HydrophobicContact CB-CZ 4.48Å; L308-F353 HydrophobicContact CD2-CD2 4.18Å; L308-F353 HydrophobicContact CD2-CE2 3.62Å; L308-F353 HydrophobicContact CD2-CZ 4.31Å; L308-V360 HydrophobicContact CD1-CB 3.81Å; L308-V360 HydrophobicContact CD1-CG1 4.05Å; L308-V360 HydrophobicContact CD1-CG2 3.76Å
309D82.8Confident79.5Confident28 Ų2846.3 Ų46.315%0.1527%0.265CS..Hα-helixtrans-60.8-37.9174-76.7-36000112.3K48 Q305 M307 C312 L313 H357K48-D309 IonicContact NZ-OD2 2.84Å; K48-D309 PolarHBondContact NZ-OD2 2.76Å; Q305-D309 PolarHBondContact NE2-OD1 3.4Å; Q305-D309 PolarHBondContact NE2-OD2 2.84Å; Q305-D309 PolarHBondContact O-N 2.67Å; M307-D309 VanDerWaalsContact C-N 3.34Å; M307-D309 PolarHBondContact O-N 3.43Å; D309-C312 WeakPolarHBondContact O-CA 3.47Å; D309-C312 VanDerWaalsContact O-CB 3.28Å; D309-C312 WeakPolarHBondContact O-CB 3.33Å; D309-C312 PolarHBondContact O-N 3.32Å; D309-L313 WeakPolarHBondContact O-CG 3.2Å; D309-L313 PolarHBondContact O-N 3.37Å; D309-H357 IonicContact OD1-NE2 3.35Å; D309-H357 PolarHBondContact OD1-NE2 3.28Å; D309-H357 VanDerWaalsContact OD1-NE2 3.15Å
310R77.6Confident78.3Confident78 Ų7848.9 Ų48.929%0.29427%0.265SS..Hα-helixtrans-64.4-40.4174.8-79.1176.960.3178.5-4112N306 M307 L308 C312 L313 G314 K315 K316 S318N306-R310 WeakPolarHBondContact O-CG 3.42Å; N306-R310 PolarHBondContact O-N 3.14Å; N306-R310 VanDerWaalsContact O-N 3.09Å; M307-R310 WeakPolarHBondContact O-CB 3.47Å; M307-R310 PolarHBondContact O-N 2.97Å; L308-R310 VanDerWaalsContact C-N 3.3Å; L308-R310 PolarHBondContact O-N 3.46Å; R310-C312 VanDerWaalsContact C-N 3.26Å; R310-C312 PolarHBondContact O-N 3.11Å; R310-L313 CarbonylContact O-C 3.58Å; R310-L313 WeakPolarHBondContact O-CA 3.42Å; R310-L313 WeakPolarHBondContact O-CB 3.39Å; R310-L313 PolarHBondContact O-N 3.24Å; R310-G314 PolarHBondContact O-N 3.46Å; R310-K315 CarbonylContact C-O 3.57Å; R310-K315 HydrophobicContact CB-CB 4.18Å; R310-K315 WeakPolarHBondContact O-CB 3.24Å; R310-K315 PolarHBondContact O-N 3.22Å; R310-K316 PolarHBondContact NH2-O 3.34Å; R310-S318 PolarHBondContact NH1-OG 2.91Å; R310-S318 PolarHBondContact NH2-OG 3.31Å
311M79.6Confident76.6Confident48 Ų4855 Ų5524%0.23630%0.298CS..Hα-helixtrans-65.1-32.7173.5-68.3-18068.800111.7M307 L308 L313 G314 K315 P317 F336 F353M307-M311 PolarHBondContact O-N 2.89Å; M307-M311 VanDerWaalsContact O-N 3.08Å; L308-M311 WeakPolarHBondContact O-CB 3.46Å; L308-M311 PolarHBondContact O-N 3.35Å; L308-M311 VanDerWaalsContact O-N 3.16Å; M311-L313 PolarHBondContact O-N 3.1Å; M311-G314 PolarHBondContact O-N 2.93Å; M311-K315 WeakPolarHBondContact CA-O 3.49Å; M311-P317 HydrophobicContact SD-CB 4.44Å; M311-P317 HydrophobicContact SD-CG 4.21Å; M311-F336 HydrophobicContact SD-CD1 3.76Å; M311-F336 HydrophobicContact SD-CE1 3.32Å; M311-F336 WeakPolarHBondContact SD-CE1 3.37Å; M311-F336 HydrophobicContact SD-CZ 4.31Å; M311-F353 HydrophobicContact CB-CE2 3.74Å; M311-F353 HydrophobicContact CB-CZ 3.77Å; M311-F353 HydrophobicContact CE-CD2 4.23Å; M311-F353 HydrophobicContact CE-CE2 3.94Å; M311-F353 HydrophobicContact CG-CE2 4.48Å; M311-F353 HydrophobicContact SD-CE2 3.98Å
312C76.8Confident74.8Confident38 Ų3861 Ų6126%0.25733%0.33SS..Hα-helixtrans-60.3-22.7168.4-690000114.7L308 D309 R310 Q349 F353L308-C312 PolarHBondContact O-N 3Å; L308-C312 PolarHBondContact O-SG 3Å; D309-C312 WeakPolarHBondContact O-CA 3.47Å; D309-C312 VanDerWaalsContact O-CB 3.28Å; D309-C312 WeakPolarHBondContact O-CB 3.33Å; D309-C312 PolarHBondContact O-N 3.32Å; R310-C312 VanDerWaalsContact C-N 3.26Å; R310-C312 PolarHBondContact O-N 3.11Å; C312-Q349 VanDerWaalsContact CA-NE2 3.28Å; C312-Q349 PolarHBondContact SG-NE2 2.95Å; C312-F353 VanDerWaalsContact SG-CE1 3.58Å
313L69.3Low73.6Confident63 Ų6362.4 Ų62.433%0.3335%0.352SS..THydrogen-bonded Turntrans-99.212.6176.9-60173.2000112.8K148 D309 R310 M311 K315K148-L313 HydrophobicContact CD-CD2 4.42Å; D309-L313 WeakPolarHBondContact O-CG 3.2Å; D309-L313 PolarHBondContact O-N 3.37Å; R310-L313 CarbonylContact O-C 3.58Å; R310-L313 WeakPolarHBondContact O-CA 3.42Å; R310-L313 WeakPolarHBondContact O-CB 3.39Å; R310-L313 PolarHBondContact O-N 3.24Å; M311-L313 PolarHBondContact O-N 3.1Å; L313-K315 HydrophobicContact CB-CG 4.43Å; L313-K315 PolarHBondContact O-N 3.46Å
314G68.8Low73.2Confident75 Ų7562.1 Ų62.177%0.77335%0.35SS*.THydrogen-bonded Turntrans69.514.2-177.500000114.1R310 M311R310-G314 PolarHBondContact O-N 3.46Å; M311-G314 PolarHBondContact O-N 2.93Å
315K70.1Confident72.8Confident104 Ų10467.7 Ų67.745%0.45237%0.374SS..PPolyproline II helixtrans-91.7141.5176.8-61.2-178.1176.1-174.30110R310 M311 L313R310-K315 CarbonylContact C-O 3.57Å; R310-K315 HydrophobicContact CB-CB 4.18Å; R310-K315 WeakPolarHBondContact O-CB 3.24Å; R310-K315 PolarHBondContact O-N 3.22Å; M311-K315 WeakPolarHBondContact CA-O 3.49Å; L313-K315 HydrophobicContact CB-CG 4.43Å; L313-K315 PolarHBondContact O-N 3.46Å
316K70.8Confident72.4Confident181 Ų18174.5 Ų74.579%0.78741%0.406SS*.PPolyproline II helixtrans-63143.3172.3-68.4-172.3177.4-174.80111.1R310 S318R310-K316 PolarHBondContact NH2-O 3.34Å; K316-S318 PolarHBondContact O-N 2.94Å
317P69.1Low72.4Confident42 Ų4273.5 Ų73.527%0.27341%0.405SS..PPolyproline II helixtrans-63.2133.1169.827.5-31.8000108.6M311 F336M311-P317 HydrophobicContact SD-CB 4.44Å; M311-P317 HydrophobicContact SD-CG 4.21Å; P317-F336 HydrophobicContact CB-CE2 4.45Å; P317-F336 HydrophobicContact CB-CZ 4.37Å
318S65.6Low72.6Confident38 Ų3873.7 Ų73.727%0.26641%0.406SS..  trans-128.6120.5167.865.90000109R310 K316 H320R310-S318 PolarHBondContact NH1-OG 2.91Å; R310-S318 PolarHBondContact NH2-OG 3.31Å; K316-S318 PolarHBondContact O-N 2.94Å; S318-H320 PolarHBondContact O-N 3.36Å; S318-H320 PolarHBondContact OG-CD2 2.89Å; S318-H320 PolarHBondContact OG-NE2 3.31Å; S318-H320 VanDerWaalsContact OG-NE2 3.08Å
319L67.9Low72.6Confident67 Ų6776.3 Ų76.335%0.35142%0.418SS..  trans-76100.3169.9-82.9150.1000107.9M307 I332M307-L319 HydrophobicContact CE-CB 4.37Å; M307-L319 HydrophobicContact CE-CD2 3.51Å; M307-L319 HydrophobicContact CE-CG 3.74Å; M307-L319 HydrophobicContact SD-CD2 4.25Å; M307-L319 HydrophobicContact SD-CG 4.2Å; L319-I332 HydrophobicContact CD2-CB 4.49Å; L319-I332 HydrophobicContact CD2-CD1 4.47Å; L319-I332 HydrophobicContact CD2-CG2 4.11Å
320H56.6Low72.8Confident118 Ų11880.4 Ų80.455%0.54644%0.436SS..  trans-85.8141.7161.4-69-74.1000108.1S318 D322S318-H320 PolarHBondContact O-N 3.36Å; S318-H320 PolarHBondContact OG-CD2 2.89Å; S318-H320 PolarHBondContact OG-NE2 3.31Å; S318-H320 VanDerWaalsContact OG-NE2 3.08Å; H320-D322 PolarHBondContact O-N 2.8Å
321N52.2Low73.5Confident128 Ų12876.7 Ų76.768%0.68442%0.422SS*.  trans-75.566.6-176.6-163.914000110.3G323 Q329N321-G323 PolarHBondContact O-N 3.33Å; N321-Q329 PolarHBondContact OD1-NE2 3.23Å
322D53.9Low74Confident126 Ų12674.4 Ų74.467%0.67441%0.411SS*.SBendtrans-82.745.2-175.4-78.7-15.9000112.2H320 L324H320-D322 PolarHBondContact O-N 2.8Å; D322-L324 VanDerWaalsContact C-N 3.3Å; D322-L324 PolarHBondContact O-N 3.48Å
323G63.3Low74.6Confident75 Ų7576.4 Ų76.477%0.77342%0.416SS*.SBendtrans74.415.3177.600000115.1N321N321-G323 PolarHBondContact O-N 3.33Å
324L76.4Confident75.6Confident17 Ų1774.1 Ų74.19%0.08941%0.407CS..  trans-71.9142.8172.1-68.3178.4000111.8A300 T303 D322 Q328 Q329 I332A300-L324 HydrophobicContact CB-CD2 3.98Å; T303-L324 HydrophobicContact CG2-CD1 3.77Å; D322-L324 VanDerWaalsContact C-N 3.3Å; D322-L324 PolarHBondContact O-N 3.48Å; L324-Q328 HydrophobicContact CB-CB 4.42Å; L324-Q328 HydrophobicContact CD2-CB 4.42Å; L324-Q329 HydrophobicContact CB-CG 3.91Å; L324-Q329 HydrophobicContact CD1-CG 4.33Å; L324-Q329 PolarHBondContact O-NE2 3.35Å; L324-I332 HydrophobicContact CD1-CD1 3.67Å
325K82.1Confident76.7Confident117 Ų11770.6 Ų70.651%0.50937%0.37SS..  trans-65.7151.1169-64.1169.5179.9162.40109.6E297 S327 Q328 Q329E297-K325 IonicContact OE1-NZ 2.85Å; E297-K325 PolarHBondContact OE1-NZ 2.99Å; K325-S327 PolarHBondContact O-N 2.87Å; K325-Q328 HydrophobicContact CB-CG 4.15Å; K325-Q328 WeakPolarHBondContact O-CB 3.36Å; K325-Q328 PolarHBondContact O-N 3.19Å; K325-Q329 PolarHBondContact O-N 3.49Å; K325-Q329 VanDerWaalsContact O-N 3.13Å
326E83.1Confident77.5Confident143 Ų14365.9 Ų65.967%0.66835%0.35SS*.Hα-helixtrans-57.1-39.1180-170.1179.1174.100112.2Q328 Q329 Q330E326-Q328 VanDerWaalsContact C-N 3.31Å; E326-Q328 PolarHBondContact O-N 3.1Å; E326-Q329 PolarHBondContact O-N 3.03Å; E326-Q330 WeakPolarHBondContact O-CG 3.13Å; E326-Q330 PolarHBondContact O-N 2.9Å
327S83.8Confident78.3Confident49 Ų4963 Ų6334%0.34334%0.339SS..Hα-helixtrans-64.1-35.4177.780.30000112.7E293 K325 Q330 S331E293-S327 WeakPolarHBondContact OE1-CB 3.45Å; E293-S327 PolarHBondContact OE1-OG 3.42Å; K325-S327 PolarHBondContact O-N 2.87Å; S327-Q330 PolarHBondContact O-N 3.47Å; S327-S331 WeakPolarHBondContact O-CB 3.42Å; S327-S331 PolarHBondContact O-N 3.47Å; S327-S331 PolarHBondContact O-OG 3.38Å
328Q87.4Confident79Confident12 Ų1262.4 Ų62.46%0.05633%0.334CS..Hα-helixtrans-68.9-40.3175.8-64171.1-34.700111.3L294 E297 A300 L324 K325 E326 Q330 S331 I332L294-Q328 HydrophobicContact CD2-CB 3.92Å; L294-Q328 HydrophobicContact CD2-CG 4.26Å; E297-Q328 VanDerWaalsContact CB-NE2 3.29Å; E297-Q328 VanDerWaalsContact CG-NE2 3.33Å; A300-Q328 HydrophobicContact CB-CG 4.28Å; L324-Q328 HydrophobicContact CB-CB 4.42Å; L324-Q328 HydrophobicContact CD2-CB 4.42Å; K325-Q328 HydrophobicContact CB-CG 4.15Å; K325-Q328 WeakPolarHBondContact O-CB 3.36Å; K325-Q328 PolarHBondContact O-N 3.19Å; E326-Q328 VanDerWaalsContact C-N 3.31Å; E326-Q328 PolarHBondContact O-N 3.1Å; Q328-Q330 VanDerWaalsContact C-N 3.35Å; Q328-S331 PolarHBondContact O-N 3.25Å; Q328-I332 VanDerWaalsContact O-CG1 3.32Å; Q328-I332 WeakPolarHBondContact O-CG1 3.42Å; Q328-I332 PolarHBondContact O-N 3.27Å
329Q86.6Confident79.6Confident55 Ų5561.6 Ų61.626%0.25733%0.327SS..Hα-helixtrans-62.7-44.1176-63.6179.210.200111.1N321 L324 K325 E326 S331 I332 Q333N321-Q329 PolarHBondContact OD1-NE2 3.23Å; L324-Q329 HydrophobicContact CB-CG 3.91Å; L324-Q329 HydrophobicContact CD1-CG 4.33Å; L324-Q329 PolarHBondContact O-NE2 3.35Å; K325-Q329 PolarHBondContact O-N 3.49Å; K325-Q329 VanDerWaalsContact O-N 3.13Å; E326-Q329 PolarHBondContact O-N 3.03Å; Q329-S331 VanDerWaalsContact C-N 3.33Å; Q329-S331 PolarHBondContact O-N 2.94Å; Q329-I332 PolarHBondContact O-N 3.09Å; Q329-Q333 WeakPolarHBondContact O-CB 3.49Å; Q329-Q333 PolarHBondContact O-N 3.29Å
330Q88.9Confident79.8Confident114 Ų11464.2 Ų64.253%0.53334%0.338SS..Hα-helixtrans-61.1-42174.5-69.1172.85.200111.6E326 S327 Q328 Q333 A334E326-Q330 WeakPolarHBondContact O-CG 3.13Å; E326-Q330 PolarHBondContact O-N 2.9Å; S327-Q330 PolarHBondContact O-N 3.47Å; Q328-Q330 VanDerWaalsContact C-N 3.35Å; Q330-Q333 PolarHBondContact O-N 3.12Å; Q330-A334 WeakPolarHBondContact O-CB 3.37Å; Q330-A334 PolarHBondContact O-N 3.47Å
331S91.3Very high79.8Confident1 Ų165.6 Ų65.61%0.00734%0.344CS..Hα-helixtrans-65.1-41.3177.1-80.40000113.2H290 E293 S327 Q328 Q329 A334 V335H290-S331 WeakPolarHBondContact ND1-CA 3.45Å; H290-S331 WeakPolarHBondContact ND1-CB 3.39Å; H290-S331 PolarHBondContact ND1-OG 2.89Å; E293-S331 PolarHBondContact OE2-OG 2.86Å; S327-S331 WeakPolarHBondContact O-CB 3.42Å; S327-S331 PolarHBondContact O-N 3.47Å; S327-S331 PolarHBondContact O-OG 3.38Å; Q328-S331 PolarHBondContact O-N 3.25Å; Q329-S331 VanDerWaalsContact C-N 3.33Å; Q329-S331 PolarHBondContact O-N 2.94Å; S331-A334 PolarHBondContact O-N 3.46Å; S331-V335 WeakPolarHBondContact O-CG2 3Å; S331-V335 PolarHBondContact O-N 2.95Å; S331-V335 VanDerWaalsContact O-N 3.1Å
332I90.5Very high79.3Confident0 Ų066.1 Ų66.10%036%0.355CS..Hα-helixtrans-62.5-45.5173.9-70.5169.4000110.5L294 T303 L304 M307 L319 L324 Q328 Q329 A334 V335 F336L294-I332 HydrophobicContact CD1-CG1 3.93Å; L294-I332 HydrophobicContact CD2-CD1 4.31Å; L294-I332 HydrophobicContact CD2-CG1 3.85Å; T303-I332 HydrophobicContact CG2-CD1 4.22Å; L304-I332 HydrophobicContact CB-CG1 4.44Å; L304-I332 HydrophobicContact CD1-CG1 4.48Å; L304-I332 HydrophobicContact CD1-CG2 4.18Å; M307-I332 HydrophobicContact SD-CG2 3.72Å; L319-I332 HydrophobicContact CD2-CB 4.49Å; L319-I332 HydrophobicContact CD2-CD1 4.47Å; L319-I332 HydrophobicContact CD2-CG2 4.11Å; L324-I332 HydrophobicContact CD1-CD1 3.67Å; Q328-I332 VanDerWaalsContact O-CG1 3.32Å; Q328-I332 WeakPolarHBondContact O-CG1 3.42Å; Q328-I332 PolarHBondContact O-N 3.27Å; Q329-I332 PolarHBondContact O-N 3.09Å; I332-A334 PolarHBondContact O-N 3.24Å; I332-V335 PolarHBondContact O-N 3.4Å; I332-F336 HydrophobicContact CG2-CD2 3.78Å; I332-F336 HydrophobicContact CG2-CE2 3.52Å; I332-F336 WeakPolarHBondContact O-CD2 3.14Å; I332-F336 PolarHBondContact O-N 3.19Å; I332-F336 VanDerWaalsContact O-N 3.15Å
333Q89.5Confident79Confident80 Ų8063.9 Ų63.937%0.37436%0.361SS..Hα-helixtrans-60.1-45.8178.8-175.859.835.400111.6Q329 Q330 V335 F336 E337Q329-Q333 WeakPolarHBondContact O-CB 3.49Å; Q329-Q333 PolarHBondContact O-N 3.29Å; Q330-Q333 PolarHBondContact O-N 3.12Å; Q333-V335 VanDerWaalsContact C-N 3.3Å; Q333-V335 PolarHBondContact O-N 2.87Å; Q333-F336 PolarHBondContact O-N 3.35Å; Q333-E337 WeakPolarHBondContact O-CG 3.32Å; Q333-E337 PolarHBondContact O-N 3.17Å
334A89.9Confident78.1Confident15 Ų1564.2 Ų64.212%0.12436%0.356CS..Hα-helixtrans-64.2-33.2178.700000113H290 Q330 S331 I332 F336 E337 V338H290-A334 VanDerWaalsContact CE1-CB 3.42Å; H290-A334 WeakPolarHBondContact CE1-CB 3.44Å; H290-A334 WeakPolarHBondContact NE2-CB 3.42Å; Q330-A334 WeakPolarHBondContact O-CB 3.37Å; Q330-A334 PolarHBondContact O-N 3.47Å; S331-A334 PolarHBondContact O-N 3.46Å; I332-A334 PolarHBondContact O-N 3.24Å; A334-F336 VanDerWaalsContact C-N 3.33Å; A334-E337 PolarHBondContact O-N 3.31Å; A334-V338 PolarHBondContact O-N 2.98Å
335V91.6Very high76.6Confident1 Ų172.1 Ų72.11%0.00639%0.393CS..Hα-helixtrans-63.9-40.4171.7170.80000110.8L287 H290 L304 S331 I332 Q333 V338L287-V335 HydrophobicContact CD2-CG1 4.4Å; L287-V335 HydrophobicContact CD2-CG2 4.33Å; H290-V335 HydrophobicContact CB-CG2 3.91Å; L304-V335 HydrophobicContact CD1-CG1 4.24Å; S331-V335 WeakPolarHBondContact O-CG2 3Å; S331-V335 PolarHBondContact O-N 2.95Å; S331-V335 VanDerWaalsContact O-N 3.1Å; I332-V335 PolarHBondContact O-N 3.4Å; Q333-V335 VanDerWaalsContact C-N 3.3Å; Q333-V335 PolarHBondContact O-N 2.87Å; V335-V338 PolarHBondContact O-N 3.34Å
336F87.7Confident75Confident5 Ų576 Ų762%0.02241%0.413CS..Hα-helixtrans-70.8-34.5177-75.7-61.7000113.6L304 M307 L308 M311 P317 I332 Q333 A334 V338 L339 E340L304-F336 HydrophobicContact CD1-CE2 3.99Å; L304-F336 HydrophobicContact CD1-CZ 4.01Å; M307-F336 HydrophobicContact CB-CE2 3.92Å; M307-F336 HydrophobicContact CB-CZ 3.51Å; M307-F336 HydrophobicContact CG-CE2 4.47Å; M307-F336 HydrophobicContact SD-CE2 3.72Å; M307-F336 HydrophobicContact SD-CZ 4.3Å; L308-F336 HydrophobicContact CD2-CE1 3.78Å; L308-F336 HydrophobicContact CD2-CZ 4.21Å; L308-F336 HydrophobicContact CG-CE1 4.47Å; L308-F336 HydrophobicContact CG-CZ 4.43Å; M311-F336 HydrophobicContact SD-CD1 3.76Å; M311-F336 HydrophobicContact SD-CE1 3.32Å; M311-F336 WeakPolarHBondContact SD-CE1 3.37Å; M311-F336 HydrophobicContact SD-CZ 4.31Å; P317-F336 HydrophobicContact CB-CE2 4.45Å; P317-F336 HydrophobicContact CB-CZ 4.37Å; I332-F336 HydrophobicContact CG2-CD2 3.78Å; I332-F336 HydrophobicContact CG2-CE2 3.52Å; I332-F336 WeakPolarHBondContact O-CD2 3.14Å; I332-F336 PolarHBondContact O-N 3.19Å; I332-F336 VanDerWaalsContact O-N 3.15Å; Q333-F336 PolarHBondContact O-N 3.35Å; A334-F336 VanDerWaalsContact C-N 3.33Å; F336-V338 PolarHBondContact O-N 3.12Å; F336-L339 HydrophobicContact CD1-CD1 3.72Å; F336-L339 HydrophobicContact CE1-CD1 3.98Å; F336-L339 CarbonylContact O-C 3.52Å; F336-L339 WeakPolarHBondContact O-CA 3.46Å; F336-L339 WeakPolarHBondContact O-CB 3.42Å; F336-L339 PolarHBondContact O-N 3.14Å; F336-E340 PolarHBondContact O-N 2.84Å
337E86.7Confident73.4Confident120 Ų12078 Ų7856%0.56142%0.422SS*.Hα-helixtrans-58.8-32.8173.6-73.1173.5-172.500112.3Q333 A334 L339Q333-E337 WeakPolarHBondContact O-CG 3.32Å; Q333-E337 PolarHBondContact O-N 3.17Å; A334-E337 PolarHBondContact O-N 3.31Å; E337-L339 VanDerWaalsContact C-N 3.29Å; E337-L339 PolarHBondContact O-N 3.24Å
338V83.4Confident72.1Confident30 Ų3081.6 Ų81.618%0.18244%0.442CS..Hα-helixtrans-70.3-28.2174176.60000112.2T283 L287 A334 V335 F336T283-V338 HydrophobicContact CG2-CB 4.46Å; T283-V338 HydrophobicContact CG2-CG1 3.44Å; T283-V338 VanDerWaalsContact CG2-CG1 3.44Å; T283-V338 HydrophobicContact CG2-CG2 4.12Å; L287-V338 HydrophobicContact CD1-CG1 3.99Å; L287-V338 HydrophobicContact CD2-CB 4.08Å; L287-V338 HydrophobicContact CD2-CG1 4.09Å; L287-V338 HydrophobicContact CD2-CG2 4.05Å; L287-V338 HydrophobicContact CG-CG1 4.21Å; L287-V338 HydrophobicContact CG-CG2 4.33Å; A334-V338 PolarHBondContact O-N 2.98Å; V335-V338 PolarHBondContact O-N 3.34Å; F336-V338 PolarHBondContact O-N 3.12Å
339L79.1Confident71.1Confident21 Ų2185.1 Ų85.111%0.1146%0.459CS..Hα-helixtrans-82.2-30.9179.3-67.6171.7000112.6L308 F336 E337 Q341 F353 L356L308-L339 HydrophobicContact CD2-CD1 3.83Å; F336-L339 HydrophobicContact CD1-CD1 3.72Å; F336-L339 HydrophobicContact CE1-CD1 3.98Å; F336-L339 CarbonylContact O-C 3.52Å; F336-L339 WeakPolarHBondContact O-CA 3.46Å; F336-L339 WeakPolarHBondContact O-CB 3.42Å; F336-L339 PolarHBondContact O-N 3.14Å; E337-L339 VanDerWaalsContact C-N 3.29Å; E337-L339 PolarHBondContact O-N 3.24Å; L339-Q341 PolarHBondContact O-N 3.26Å; L339-Q341 VanDerWaalsContact O-N 3.14Å; L339-F353 HydrophobicContact CD1-CD2 4.04Å; L339-F353 HydrophobicContact CD2-CB 3.88Å; L339-F353 HydrophobicContact CD2-CD2 4.1Å; L339-F353 HydrophobicContact CD2-CG 4.47Å; L339-L356 HydrophobicContact CD1-CD1 4.46Å; L339-L356 HydrophobicContact CD2-CD1 3.5Å; L339-L356 HydrophobicContact CG-CD1 3.99Å
340E72.3Confident70.9Confident122 Ų12284.7 Ų84.757%0.5746%0.462SS*.  trans-82.978.8179.1-68.4-174.4170.500111.3F336F336-E340 PolarHBondContact O-N 2.84Å
341Q56.6Low70.8Confident147 Ų14783 Ų8369%0.68746%0.46SS*.  trans-84.1128.1166.9-66.2-160.67.300110.8L339 G343L339-Q341 PolarHBondContact O-N 3.26Å; L339-Q341 VanDerWaalsContact O-N 3.14Å; Q341-G343 PolarHBondContact O-N 2.94Å; Q341-G343 VanDerWaalsContact O-N 3.07Å
342P40.4Very low70.7Confident139 Ų13984 Ų8490%0.90347%0.467SS*.THydrogen-bonded Turntrans-69.7106.3-179.426.4-31.5000110.3
343G47.7Very low70.7Confident78 Ų7884.5 Ų84.580%0.80447%0.469SS*.THydrogen-bonded Turntrans138.60.3169.900000117.7Q341Q341-G343 PolarHBondContact O-N 2.94Å; Q341-G343 VanDerWaalsContact O-N 3.07Å
344A45.5Very low70.7Confident82 Ų8282.4 Ų82.468%0.67846%0.462SS*.  trans-82122.4177.800000111.6
345E44.3Very low70.9Confident184 Ų18481.7 Ų81.786%0.8646%0.456SS*.  trans-56.8137.3172-66.4178.216900110.9Q347E345-Q347 PolarHBondContact O-N 2.85Å
346E49.3Very low71Confident199 Ų19981.7 Ų81.793%0.9346%0.456SS*.THydrogen-bonded Turntrans-62.212.1-162.1-69.2-178.4144.900117.6
347Q49.3Very low71.2Confident183 Ų18381.7 Ų81.786%0.85546%0.456SS*.THydrogen-bonded Turntrans-124.3-11.4-165.3-66.5178.32300116.6E345E345-Q347 PolarHBondContact O-N 2.85Å
348T55.3Low71.6Confident126 Ų12676 Ų7677%0.77343%0.429SS*.SBendtrans-124.5120.7174.7-51.70000110.8S350T348-S350 PolarHBondContact O-N 3.4Å
349Q67.3Low72.2Confident86 Ų8674.6 Ų74.640%0.40242%0.421SS..  trans-57.9134.7173.9-66.8-176.8-27.400110.2C312 F353C312-Q349 VanDerWaalsContact CA-NE2 3.28Å; C312-Q349 PolarHBondContact SG-NE2 2.95Å; Q349-F353 HydrophobicContact CB-CD1 4.01Å; Q349-F353 HydrophobicContact CG-CD1 4.18Å; Q349-F353 HydrophobicContact CG-CE1 4.32Å
350S82.4Confident72.9Confident46 Ų4673.6 Ų73.632%0.32242%0.416SS..  trans-65144179.775.20000110.4T348 V352 F353 T354T348-S350 PolarHBondContact O-N 3.4Å; S350-V352 PolarHBondContact O-N 2.92Å; S350-V352 VanDerWaalsContact O-N 3.13Å; S350-F353 WeakPolarHBondContact O-CA 3.39Å; S350-F353 VanDerWaalsContact O-CB 3.3Å; S350-F353 WeakPolarHBondContact O-CB 3.43Å; S350-F353 PolarHBondContact O-N 2.69Å; S350-F353 WeakPolarHBondContact OG-CB 3.48Å; S350-F353 PolarHBondContact OG-N 2.65Å; S350-T354 PolarHBondContact O-N 3.03Å; S350-T354 VanDerWaalsContact O-N 3.1Å; S350-T354 PolarHBondContact O-OG1 3.13Å
351P87.1Confident73.9Confident77 Ų7767.8 Ų67.850%0.539%0.388SS..Hα-helixtrans-55.1-31.5175-27.835.3000113.2Q275 T354 A355Q275-P351 HydrophobicContact CG-CB 3.96Å; P351-T354 PolarHBondContact O-N 3.05Å; P351-A355 WeakPolarHBondContact O-CB 3.46Å; P351-A355 PolarHBondContact O-N 2.78Å
352V89.4Confident75.7Confident24 Ų2460.8 Ų60.815%0.14536%0.356CS..Hα-helixtrans-66.6-42174.7-179.50000111.2L279 S350 A355 L356L279-V352 HydrophobicContact CD1-CG1 4.22Å; L279-V352 HydrophobicContact CD2-CG1 4.06Å; L279-V352 HydrophobicContact CD2-CG2 3.87Å; S350-V352 PolarHBondContact O-N 2.92Å; S350-V352 VanDerWaalsContact O-N 3.13Å; V352-A355 PolarHBondContact O-N 3.02Å; V352-L356 HydrophobicContact CG1-CD1 4.2Å; V352-L356 WeakPolarHBondContact O-CB 3.49Å; V352-L356 PolarHBondContact O-N 3.04Å
353F90.3Very high78.3Confident10 Ų1054.2 Ų54.24%0.04431%0.313CS..Hα-helixtrans-58.8-48.4173.4173.5-88000111.2L308 M311 C312 L339 Q349 S350 A355 L356 H357L308-F353 HydrophobicContact CB-CZ 4.48Å; L308-F353 HydrophobicContact CD2-CD2 4.18Å; L308-F353 HydrophobicContact CD2-CE2 3.62Å; L308-F353 HydrophobicContact CD2-CZ 4.31Å; M311-F353 HydrophobicContact CB-CE2 3.74Å; M311-F353 HydrophobicContact CB-CZ 3.77Å; M311-F353 HydrophobicContact CE-CD2 4.23Å; M311-F353 HydrophobicContact CE-CE2 3.94Å; M311-F353 HydrophobicContact CG-CE2 4.48Å; M311-F353 HydrophobicContact SD-CE2 3.98Å; C312-F353 VanDerWaalsContact SG-CE1 3.58Å; L339-F353 HydrophobicContact CD1-CD2 4.04Å; L339-F353 HydrophobicContact CD2-CB 3.88Å; L339-F353 HydrophobicContact CD2-CD2 4.1Å; L339-F353 HydrophobicContact CD2-CG 4.47Å; Q349-F353 HydrophobicContact CB-CD1 4.01Å; Q349-F353 HydrophobicContact CG-CD1 4.18Å; Q349-F353 HydrophobicContact CG-CE1 4.32Å; S350-F353 WeakPolarHBondContact O-CA 3.39Å; S350-F353 VanDerWaalsContact O-CB 3.3Å; S350-F353 WeakPolarHBondContact O-CB 3.43Å; S350-F353 PolarHBondContact O-N 2.69Å; S350-F353 WeakPolarHBondContact OG-CB 3.48Å; S350-F353 PolarHBondContact OG-N 2.65Å; F353-A355 VanDerWaalsContact C-N 3.31Å; F353-A355 PolarHBondContact O-N 2.92Å; F353-L356 PolarHBondContact O-N 3.01Å; F353-H357 WeakPolarHBondContact O-CB 3.46Å; F353-H357 PolarHBondContact O-N 3.21Å
354T90.4Very high80.5Confident36 Ų3652.9 Ų52.922%0.22129%0.286CS..Hα-helixtrans-62.8-39.2179.2-51.20000111.6W42 H272 S350 P351 H357 L358W42-T354 HydrophobicContact CH2-CG2 3.76Å; W42-T354 HydrophobicContact CZ2-CG2 4.11Å; H272-T354 WeakPolarHBondContact NE2-CG2 3.44Å; S350-T354 PolarHBondContact O-N 3.03Å; S350-T354 VanDerWaalsContact O-N 3.1Å; S350-T354 PolarHBondContact O-OG1 3.13Å; P351-T354 PolarHBondContact O-N 3.05Å; T354-H357 PolarHBondContact O-N 3.44Å; T354-L358 PolarHBondContact O-N 2.88Å
355A93.1Very high82.6Confident0 Ų049.5 Ų49.50%026%0.256CS..Hα-helixtrans-67.8-38.5175.800000112.9H272 Q275 L276 P351 V352 F353 L358 V359H272-A355 HydrophobicContact CB-CB 4.15Å; H272-A355 WeakPolarHBondContact O-CB 3.48Å; Q275-A355 HydrophobicContact CB-CB 4.06Å; L276-A355 HydrophobicContact CD2-CB 3.83Å; L276-A355 HydrophobicContact CG-CB 3.93Å; P351-A355 WeakPolarHBondContact O-CB 3.46Å; P351-A355 PolarHBondContact O-N 2.78Å; V352-A355 PolarHBondContact O-N 3.02Å; F353-A355 VanDerWaalsContact C-N 3.31Å; F353-A355 PolarHBondContact O-N 2.92Å; A355-L358 VanDerWaalsContact O-CB 3.27Å; A355-L358 WeakPolarHBondContact O-CB 3.39Å; A355-L358 PolarHBondContact O-N 3.49Å; A355-V359 WeakPolarHBondContact O-CG2 3.31Å; A355-V359 PolarHBondContact O-N 3.49Å; A355-V359 VanDerWaalsContact O-N 3.16Å
356L93.5Very high84.8Confident1 Ų140.9 Ų40.91%0.00522%0.216CC..Hα-helixtrans-68.8-40.9174-81.6172.3000112.1L276 L287 I291 L339 V352 F353 L358 V359 V360L276-L356 HydrophobicContact CD2-CD2 4.26Å; L276-L356 HydrophobicContact CD2-CG 4.32Å; L287-L356 HydrophobicContact CD1-CD1 4.32Å; L287-L356 HydrophobicContact CD1-CD2 4.19Å; L287-L356 HydrophobicContact CD2-CD1 4.1Å; L287-L356 HydrophobicContact CD2-CD2 4.16Å; I291-L356 HydrophobicContact CD1-CD2 4.1Å; L339-L356 HydrophobicContact CD1-CD1 4.46Å; L339-L356 HydrophobicContact CD2-CD1 3.5Å; L339-L356 HydrophobicContact CG-CD1 3.99Å; V352-L356 HydrophobicContact CG1-CD1 4.2Å; V352-L356 WeakPolarHBondContact O-CB 3.49Å; V352-L356 PolarHBondContact O-N 3.04Å; F353-L356 PolarHBondContact O-N 3.01Å; L356-L358 PolarHBondContact O-N 3.47Å; L356-V359 PolarHBondContact O-N 3.4Å; L356-V359 VanDerWaalsContact O-N 3.14Å; L356-V360 WeakPolarHBondContact O-CG2 3.45Å; L356-V360 PolarHBondContact O-N 2.96Å
357H92.9Very high86.6Confident5 Ų532.1 Ų32.12%0.02318%0.176CC..Hα-helixtrans-57.3-40.1171.4-178.9-85.8000111S41 W42 Q305 D309 F353 T354 S361S41-H357 VanDerWaalsContact CB-CE1 3.41Å; S41-H357 WeakPolarHBondContact CB-CE1 3.31Å; W42-H357 AromaticContact CD1-CE1 3.91Å; W42-H357 AromaticContact CD1-ND1 3.99Å; W42-H357 AromaticContact CE2-ND1 3.61Å; W42-H357 AromaticContact CZ2-ND1 3.81Å; W42-H357 AromaticContact NE1-CE1 3.36Å; W42-H357 PolarHBondContact NE1-CE1 2.9Å; W42-H357 AromaticContact NE1-ND1 3.01Å; W42-H357 PolarHBondContact NE1-ND1 3.02Å; Q305-H357 PolarHBondContact NE2-NE2 3.2Å; D309-H357 IonicContact OD1-NE2 3.35Å; D309-H357 PolarHBondContact OD1-NE2 3.28Å; D309-H357 VanDerWaalsContact OD1-NE2 3.15Å; F353-H357 WeakPolarHBondContact O-CB 3.46Å; F353-H357 PolarHBondContact O-N 3.21Å; T354-H357 PolarHBondContact O-N 3.44Å; H357-S361 PolarHBondContact CE1-OG 2.97Å; H357-S361 WeakPolarHBondContact O-CB 3.5Å; H357-S361 PolarHBondContact O-N 3.05Å; H357-S361 PolarHBondContact O-OG 3.04Å
358L94.3Very high88.1Confident0 Ų026.5 Ų26.50%015%0.152CC..Hα-helixtrans-57.1-49.5172.9-17876.7000112.3W42 W44 L269 H272 F273 T354 A355 L356 A362 I449W42-L358 HydrophobicContact CD2-CD1 3.75Å; W42-L358 HydrophobicContact CE3-CD1 3.89Å; W42-L358 HydrophobicContact CG-CD1 4.4Å; W42-L358 HydrophobicContact CH2-CB 4.19Å; W42-L358 HydrophobicContact CH2-CD1 3.87Å; W42-L358 HydrophobicContact CZ2-CB 3.63Å; W42-L358 HydrophobicContact CZ2-CD1 3.73Å; W42-L358 HydrophobicContact CZ2-CG 4.33Å; W42-L358 HydrophobicContact CZ3-CD1 3.95Å; W44-L358 HydrophobicContact CH2-CD1 3.29Å; W44-L358 HydrophobicContact CZ2-CD1 3.29Å; W44-L358 HydrophobicContact CZ2-CG 4.5Å; L269-L358 HydrophobicContact CB-CD2 4.46Å; L269-L358 HydrophobicContact CD1-CD1 4.23Å; L269-L358 HydrophobicContact CD2-CD1 3.98Å; H272-L358 HydrophobicContact CB-CD2 3.58Å; F273-L358 HydrophobicContact CD1-CD2 4.42Å; F273-L358 HydrophobicContact CE1-CD2 3.92Å; F273-L358 HydrophobicContact CZ-CD2 4.41Å; T354-L358 PolarHBondContact O-N 2.88Å; A355-L358 VanDerWaalsContact O-CB 3.27Å; A355-L358 WeakPolarHBondContact O-CB 3.39Å; A355-L358 PolarHBondContact O-N 3.49Å; L356-L358 PolarHBondContact O-N 3.47Å; L358-A362 WeakPolarHBondContact O-CB 3.41Å; L358-A362 PolarHBondContact O-N 3.32Å; L358-I449 HydrophobicContact CD1-CG2 4.3Å; L358-I449 HydrophobicContact CD2-CG2 4.44Å; L358-I449 HydrophobicContact CG-CG2 4.16Å
359V95.3Very high89.2Confident0 Ų023.4 Ų23.40%013%0.13CC..Hα-helixtrans-60.7-54.1-178.6-1730000110.7L276 I291 A355 L356 S361 A362 L363L276-V359 HydrophobicContact CD1-CG2 3.5Å; L276-V359 VanDerWaalsContact CD1-CG2 3.5Å; L276-V359 HydrophobicContact CD2-CG2 4.37Å; I291-V359 HydrophobicContact CD1-CG1 4.49Å; A355-V359 WeakPolarHBondContact O-CG2 3.31Å; A355-V359 PolarHBondContact O-N 3.49Å; A355-V359 VanDerWaalsContact O-N 3.16Å; L356-V359 PolarHBondContact O-N 3.4Å; L356-V359 VanDerWaalsContact O-N 3.14Å; V359-S361 VanDerWaalsContact C-N 3.3Å; V359-S361 PolarHBondContact O-N 2.66Å; V359-A362 PolarHBondContact O-N 3.45Å; V359-A362 VanDerWaalsContact O-N 3.14Å; V359-L363 HydrophobicContact CG1-CD1 4.03Å; V359-L363 HydrophobicContact CG1-CG 4.48Å; V359-L363 WeakPolarHBondContact O-CG 3.45Å; V359-L363 PolarHBondContact O-N 2.87Å
360V95Very high90.1Very high1 Ų119.3 Ų19.31%0.00611%0.111CC..Hα-helixtrans-64.7-38.6-175.3179.20000110.7I301 L304 Q305 L308 L356 A362 L363 E364I301-V360 HydrophobicContact CG2-CG1 4.36Å; L304-V360 HydrophobicContact CB-CG1 4.29Å; L304-V360 HydrophobicContact CD2-CG1 4.11Å; L304-V360 HydrophobicContact CD2-CG2 3.61Å; L304-V360 HydrophobicContact CG-CG1 4.01Å; L304-V360 HydrophobicContact CG-CG2 4.13Å; Q305-V360 HydrophobicContact CB-CG1 3.81Å; L308-V360 HydrophobicContact CD1-CB 3.81Å; L308-V360 HydrophobicContact CD1-CG1 4.05Å; L308-V360 HydrophobicContact CD1-CG2 3.76Å; L356-V360 WeakPolarHBondContact O-CG2 3.45Å; L356-V360 PolarHBondContact O-N 2.96Å; V360-A362 VanDerWaalsContact C-N 3.35Å; V360-A362 PolarHBondContact O-N 3.36Å; V360-L363 PolarHBondContact O-N 3.34Å; V360-E364 WeakPolarHBondContact O-CB 3.43Å; V360-E364 PolarHBondContact O-N 3.19Å
361S93Very high90.4Very high0 Ų017.2 Ų17.20%010%0.097CC..Hα-helixtrans-64.1-36.7174.9-71.60000113.3W42 Q45 Q305 H357 V359 E365W42-S361 VanDerWaalsContact CD1-CB 3.43Å; W42-S361 PolarHBondContact NE1-OG 3.18Å; Q45-S361 PolarHBondContact NE2-OG 3.36Å; Q305-S361 PolarHBondContact NE2-OG 3.4Å; Q305-S361 VanDerWaalsContact OE1-CA 3.27Å; Q305-S361 VanDerWaalsContact OE1-N 3.08Å; Q305-S361 PolarHBondContact OE1-OG 3.16Å; H357-S361 PolarHBondContact CE1-OG 2.97Å; H357-S361 WeakPolarHBondContact O-CB 3.5Å; H357-S361 PolarHBondContact O-N 3.05Å; H357-S361 PolarHBondContact O-OG 3.04Å; V359-S361 VanDerWaalsContact C-N 3.3Å; V359-S361 PolarHBondContact O-N 2.66Å; S361-E365 WeakPolarHBondContact O-CG 3.22Å; S361-E365 PolarHBondContact O-N 2.91Å
362A94.9Very high90.5Very high0 Ų015.7 Ų15.70%09%0.087CC..Hα-helixtrans-70-40.5175.300000111.1L358 V359 V360 E365 L366 I446 I449 A450L358-A362 WeakPolarHBondContact O-CB 3.41Å; L358-A362 PolarHBondContact O-N 3.32Å; V359-A362 PolarHBondContact O-N 3.45Å; V359-A362 VanDerWaalsContact O-N 3.14Å; V360-A362 VanDerWaalsContact C-N 3.35Å; V360-A362 PolarHBondContact O-N 3.36Å; A362-E365 PolarHBondContact O-N 3Å; A362-L366 PolarHBondContact O-N 3.12Å; A362-I446 HydrophobicContact CB-CG2 4.47Å; A362-I446 WeakPolarHBondContact O-CG2 3.43Å; A362-I449 HydrophobicContact CB-CB 4.2Å; A362-I449 HydrophobicContact CB-CG2 3.72Å; A362-A450 HydrophobicContact CB-CB 4.19Å
363L95.2Very high90.5Very high0 Ų015 Ų150%08%0.083CC..Hα-helixtrans-65-44.4176.9-67.4173.7000112.1I291 M295 I301 V359 V360 E365 L366 L371 L374 A450 L454I291-L363 HydrophobicContact CG2-CD1 3.48Å; I291-L363 VanDerWaalsContact CG2-CD1 3.48Å; M295-L363 HydrophobicContact CE-CD2 3.9Å; M295-L363 HydrophobicContact CG-CD1 4.05Å; M295-L363 HydrophobicContact CG-CD2 4.43Å; M295-L363 HydrophobicContact SD-CD1 3.93Å; M295-L363 HydrophobicContact SD-CD2 4Å; I301-L363 HydrophobicContact CD1-CD1 4.32Å; I301-L363 HydrophobicContact CG2-CB 4.02Å; V359-L363 HydrophobicContact CG1-CD1 4.03Å; V359-L363 HydrophobicContact CG1-CG 4.48Å; V359-L363 WeakPolarHBondContact O-CG 3.45Å; V359-L363 PolarHBondContact O-N 2.87Å; V360-L363 PolarHBondContact O-N 3.34Å; L363-E365 PolarHBondContact O-N 3.35Å; L363-L366 HydrophobicContact CD2-CD1 4.17Å; L363-L366 WeakPolarHBondContact O-CB 3.35Å; L363-L366 PolarHBondContact O-N 2.89Å; L363-L366 VanDerWaalsContact O-N 3.13Å; L363-L371 HydrophobicContact CB-CD2 3.94Å; L363-L371 HydrophobicContact CD2-CD2 3.9Å; L363-L371 HydrophobicContact CG-CD2 4.49Å; L363-L371 WeakPolarHBondContact O-CD2 3.04Å; L363-L374 HydrophobicContact CD2-CD2 4.28Å; L363-A450 HydrophobicContact CD2-CB 4.08Å; L363-L454 HydrophobicContact CD2-CD1 4.29Å
364E92.4Very high90.5Very high50 Ų5014.6 Ų14.623%0.2348%0.081CC..Hα-helixtrans-63.6-28-179.9-171.8-97.9173.900113.3I301 Q305 V360I301-E364 HydrophobicContact CG2-CB 3.93Å; Q305-E364 HydrophobicContact CB-CB 4.36Å; Q305-E364 HydrophobicContact CB-CG 4.24Å; Q305-E364 HydrophobicContact CG-CB 4.39Å; Q305-E364 HydrophobicContact CG-CG 4.26Å; V360-E364 WeakPolarHBondContact O-CB 3.43Å; V360-E364 PolarHBondContact O-N 3.19Å
365E90.8Very high90.5Very high12 Ų1213.4 Ų13.46%0.0567%0.074CC..THydrogen-bonded Turntrans-85.2-10.4177.2-72.1-69.8171.300114Q45 K46 S361 A362 L363 Y443 I446Q45-E365 WeakPolarHBondContact CA-OE1 3.46Å; Q45-E365 HydrophobicContact CG-CG 4.11Å; K46-E365 WeakPolarHBondContact CB-OE1 3.3Å; K46-E365 WeakPolarHBondContact CD-OE2 3.36Å; K46-E365 WeakPolarHBondContact CG-OE2 3.38Å; K46-E365 PolarHBondContact N-OE1 2.73Å; S361-E365 WeakPolarHBondContact O-CG 3.22Å; S361-E365 PolarHBondContact O-N 2.91Å; A362-E365 PolarHBondContact O-N 3Å; L363-E365 PolarHBondContact O-N 3.35Å; E365-Y443 WeakPolarHBondContact O-CE1 3.22Å; E365-I446 HydrophobicContact CB-CD1 4.02Å; E365-I446 HydrophobicContact CB-CG2 3.99Å
366L90.6Very high90.3Very high3 Ų316.9 Ų16.92%0.01610%0.095CC..SBendtrans-67.8154.8174-72.4175.9000110.8A362 L363 D368 L371 L374 I446 L447 A450A362-L366 PolarHBondContact O-N 3.12Å; L363-L366 HydrophobicContact CD2-CD1 4.17Å; L363-L366 WeakPolarHBondContact O-CB 3.35Å; L363-L366 PolarHBondContact O-N 2.89Å; L363-L366 VanDerWaalsContact O-N 3.13Å; L366-D368 PolarHBondContact O-N 3.1Å; L366-L371 HydrophobicContact CB-CD2 4.43Å; L366-L371 HydrophobicContact CB-CG 4.39Å; L366-L371 HydrophobicContact CD1-CD2 4.23Å; L366-L374 HydrophobicContact CD1-CD2 3.9Å; L366-I446 HydrophobicContact CD2-CG2 3.84Å; L366-I446 HydrophobicContact CG-CG2 4.14Å; L366-L447 HydrophobicContact CD2-CB 4.22Å; L366-L447 HydrophobicContact CD2-CD1 4.31Å; L366-A450 HydrophobicContact CD1-CB 3.95Å
367P85.4Confident90Very high15 Ų1516.9 Ų16.910%0.09710%0.095CC..  trans-55.8137.4170.8-23.134.1000111.7D369 C370 Y443P367-D369 WeakPolarHBondContact CB-OD1 3.24Å; P367-D369 PolarHBondContact O-N 2.78Å; P367-D369 VanDerWaalsContact O-N 3.13Å; P367-C370 HydrophobicContact CB-CB 4.37Å; P367-C370 VanDerWaalsContact O-CB 3.29Å; P367-C370 WeakPolarHBondContact O-CB 3.47Å; P367-C370 PolarHBondContact O-N 3.39Å; P367-Y443 HydrophobicContact CG-CD1 4.27Å; P367-Y443 HydrophobicContact CG-CE1 4.09Å
368D81.1Confident89.8Confident65 Ų6517.2 Ų17.235%0.34810%0.098SC..THydrogen-bonded Turntrans-58.3-30.3-174-58.9-12.6000112.2K7 P298 L366 P372K7-D368 VanDerWaalsContact NZ-CG 3.31Å; K7-D368 IonicContact NZ-OD1 3.06Å; K7-D368 PolarHBondContact NZ-OD1 2.95Å; K7-D368 IonicContact NZ-OD2 3.37Å; K7-D368 PolarHBondContact NZ-OD2 2.96Å; P298-D368 HydrophobicContact CB-CB 4.21Å; P298-D368 HydrophobicContact CG-CB 3.99Å; P298-D368 VanDerWaalsContact CG-O 3.29Å; P298-D368 WeakPolarHBondContact CG-O 3.49Å; L366-D368 PolarHBondContact O-N 3.1Å; D368-P372 VanDerWaalsContact O-CD 3.25Å; D368-P372 WeakPolarHBondContact O-CD 3.42Å
369D79.2Confident89.5Confident60 Ų6020.2 Ų20.232%0.32111%0.114SC..THydrogen-bonded Turntrans-73.8-24.7175.459.3-44.4000113.6P367 S420P367-D369 WeakPolarHBondContact CB-OD1 3.24Å; P367-D369 PolarHBondContact O-N 2.78Å; P367-D369 VanDerWaalsContact O-N 3.13Å; D369-S420 PolarHBondContact OD2-OG 3.33Å
370C86.3Confident89.2Confident0 Ų023.2 Ų23.20%013%0.133CC..Hα-helixtrans-76-34.9179-67.70000112.9P367 V373 L374 S420P367-C370 HydrophobicContact CB-CB 4.37Å; P367-C370 VanDerWaalsContact O-CB 3.29Å; P367-C370 WeakPolarHBondContact O-CB 3.47Å; P367-C370 PolarHBondContact O-N 3.39Å; C370-V373 PolarHBondContact O-N 3.03Å; C370-L374 WeakPolarHBondContact O-CB 3.23Å; C370-L374 PolarHBondContact O-N 3.41Å; C370-S420 WeakPolarHBondContact SG-CB 3.25Å
371L88.8Confident88.9Confident3 Ų326.3 Ų26.32%0.01616%0.159CC..Hα-helixtrans-60.2-49.4-171.1-80.6173.6000113.1M295 P298 L363 L366 V373 L374 S375M295-L371 HydrophobicContact CE-CD2 4.37Å; M295-L371 HydrophobicContact CG-CD2 4.22Å; M295-L371 CarbonylContact O-C 3.42Å; M295-L371 VanDerWaalsContact O-C 3.27Å; P298-L371 HydrophobicContact CB-CD1 4.04Å; P298-L371 HydrophobicContact CG-CB 4.47Å; P298-L371 HydrophobicContact CG-CD1 4.26Å; L363-L371 HydrophobicContact CB-CD2 3.94Å; L363-L371 HydrophobicContact CD2-CD2 3.9Å; L363-L371 HydrophobicContact CG-CD2 4.49Å; L363-L371 WeakPolarHBondContact O-CD2 3.04Å; L366-L371 HydrophobicContact CB-CD2 4.43Å; L366-L371 HydrophobicContact CB-CG 4.39Å; L366-L371 HydrophobicContact CD1-CD2 4.23Å; L371-V373 VanDerWaalsContact C-N 3.34Å; L371-V373 PolarHBondContact O-N 3.34Å; L371-L374 PolarHBondContact O-N 3.3Å; L371-S375 PolarHBondContact O-N 3.12Å
372P88.5Confident88.7Confident45 Ų4526.5 Ų26.529%0.29216%0.16SC..Hα-helixtrans-63.2-39.3177.3-23.134.5000112.4D368 S375 V376D368-P372 VanDerWaalsContact O-CD 3.25Å; D368-P372 WeakPolarHBondContact O-CD 3.42Å; P372-S375 WeakPolarHBondContact O-CB 3.34Å; P372-S375 PolarHBondContact O-N 3.36Å; P372-S375 PolarHBondContact O-OG 2.97Å; P372-V376 PolarHBondContact O-N 3.46Å
373V88.7Confident88.6Confident9 Ų926.5 Ų26.56%0.05516%0.16CC..Hα-helixtrans-67.6-42.7179.5-177.30000111.2M86 C370 L371 S375 V376 C377 R413 V417M86-V373 HydrophobicContact CE-CG2 4.35Å; M86-V373 HydrophobicContact SD-CG2 4.24Å; C370-V373 PolarHBondContact O-N 3.03Å; L371-V373 VanDerWaalsContact C-N 3.34Å; L371-V373 PolarHBondContact O-N 3.34Å; V373-S375 VanDerWaalsContact C-N 3.28Å; V373-S375 PolarHBondContact O-N 2.83Å; V373-V376 PolarHBondContact O-N 2.85Å; V373-C377 PolarHBondContact O-SG 2.86Å; V373-R413 HydrophobicContact CG1-CB 3.77Å; V373-R413 HydrophobicContact CG1-CG 4.08Å; V373-V417 HydrophobicContact CB-CG2 3.88Å; V373-V417 HydrophobicContact CG1-CG2 3.66Å
374L91.1Very high88.3Confident2 Ų232.6 Ų32.61%0.0119%0.189CC..Hα-helixtrans-63.8-35.1175.5-175.562.2000111.4M295 L363 L366 C370 L371 V376 C377 C378 L386 V417 L454M295-L374 HydrophobicContact CE-CB 3.84Å; M295-L374 HydrophobicContact CE-CD2 3.76Å; M295-L374 HydrophobicContact CE-CG 3.66Å; L363-L374 HydrophobicContact CD2-CD2 4.28Å; L366-L374 HydrophobicContact CD1-CD2 3.9Å; C370-L374 WeakPolarHBondContact O-CB 3.23Å; C370-L374 PolarHBondContact O-N 3.41Å; L371-L374 PolarHBondContact O-N 3.3Å; L374-V376 VanDerWaalsContact C-N 3.26Å; L374-V376 PolarHBondContact O-N 2.89Å; L374-C377 WeakPolarHBondContact O-CA 3.44Å; L374-C377 WeakPolarHBondContact O-CB 3.49Å; L374-C377 PolarHBondContact O-N 3.11Å; L374-C378 PolarHBondContact O-N 2.91Å; L374-C378 PolarHBondContact O-SG 3.45Å; L374-C378 VanDerWaalsContact O-SG 3.34Å; L374-L386 HydrophobicContact CD1-CD1 4.28Å; L374-V417 HydrophobicContact CB-CG2 4.39Å; L374-L454 HydrophobicContact CD2-CD1 4.06Å; L374-L454 HydrophobicContact CG-CD1 4.33Å
375S91Very high88.2Confident11 Ų1130.6 Ų30.68%0.07718%0.181CC..Hα-helixtrans-59.5-36.517882.70000112.5T292 L371 P372 V373 C377 C378T292-S375 WeakPolarHBondContact CG2-O 3.39Å; L371-S375 PolarHBondContact O-N 3.12Å; P372-S375 WeakPolarHBondContact O-CB 3.34Å; P372-S375 PolarHBondContact O-N 3.36Å; P372-S375 PolarHBondContact O-OG 2.97Å; V373-S375 VanDerWaalsContact C-N 3.28Å; V373-S375 PolarHBondContact O-N 2.83Å; S375-C377 PolarHBondContact O-N 3.34Å; S375-C378 WeakPolarHBondContact O-CB 3.24Å; S375-C378 PolarHBondContact O-N 3.47Å
376V88.3Confident88.2Confident72 Ų7230.1 Ų30.144%0.43618%0.179SC..Hα-helixtrans-70.3-25.7176.5-178.50000111.5P372 V373 L374 C378P372-V376 PolarHBondContact O-N 3.46Å; V373-V376 PolarHBondContact O-N 2.85Å; L374-V376 VanDerWaalsContact C-N 3.26Å; L374-V376 PolarHBondContact O-N 2.89Å; V376-C378 VanDerWaalsContact C-N 3.3Å; V376-C378 PolarHBondContact O-N 3.27Å
377C87.7Confident88.2Confident1 Ų132.5 Ų32.51%0.00719%0.19CC..THydrogen-bonded Turntrans-83.9-0.8178.7-55.90000113.3V373 L374 S375 N379 T382 L386V373-C377 PolarHBondContact O-SG 2.86Å; L374-C377 WeakPolarHBondContact O-CA 3.44Å; L374-C377 WeakPolarHBondContact O-CB 3.49Å; L374-C377 PolarHBondContact O-N 3.11Å; S375-C377 PolarHBondContact O-N 3.34Å; C377-N379 PolarHBondContact O-N 3.23Å; C377-T382 HydrophobicContact CB-CG2 3.97Å; C377-T382 WeakPolarHBondContact O-CB 3.33Å; C377-L386 HydrophobicContact CB-CD1 4.13Å
378C88.6Confident88.4Confident13 Ų1333.9 Ų33.99%0.08820%0.196CC..  trans-76.519.9-174.4-730000115.4L288 T292 L374 S375 V376 L383L288-C378 HydrophobicContact CD1-CB 4.5Å; T292-C378 HydrophobicContact CG2-CB 3.73Å; T292-C378 WeakPolarHBondContact OG1-CB 3.19Å; L374-C378 PolarHBondContact O-N 2.91Å; L374-C378 PolarHBondContact O-SG 3.45Å; L374-C378 VanDerWaalsContact O-SG 3.34Å; S375-C378 WeakPolarHBondContact O-CB 3.24Å; S375-C378 PolarHBondContact O-N 3.47Å; V376-C378 VanDerWaalsContact C-N 3.3Å; V376-C378 PolarHBondContact O-N 3.27Å; C378-L383 HydrophobicContact CB-CD1 4.31Å; C378-L383 WeakPolarHBondContact O-CD1 3.3Å
379N88.6Confident88.7Confident62 Ų6230.8 Ų30.833%0.33218%0.18SC..SBendtrans-78.9151.8170.57774.1000110.5C377 A381 T382 L383C377-N379 PolarHBondContact O-N 3.23Å; N379-A381 VanDerWaalsContact C-N 3.34Å; N379-A381 PolarHBondContact O-N 3.13Å; N379-A381 PolarHBondContact OD1-N 3.39Å; N379-T382 WeakPolarHBondContact ND2-CB 3.3Å; N379-T382 PolarHBondContact ND2-OG1 3.03Å; N379-T382 PolarHBondContact O-N 3.04Å; N379-T382 PolarHBondContact OD1-N 3.38Å; N379-T382 PolarHBondContact OD1-OG1 3.01Å; N379-L383 WeakPolarHBondContact O-CB 3.35Å; N379-L383 WeakPolarHBondContact O-CG 3.35Å; N379-L383 PolarHBondContact O-N 3.37Å
380P87.9Confident89.1Confident63 Ų6328.2 Ų28.241%0.40917%0.166SC..Hα-helixtrans-58.3-38.9-172.5-27.835.5000115Q384 A458P380-Q384 WeakPolarHBondContact O-CB 3.36Å; P380-Q384 PolarHBondContact O-N 2.94Å; P380-A458 HydrophobicContact CB-CB 4.45Å
381A88Confident89Confident66 Ų6630.4 Ų30.455%0.54518%0.176SC..Hα-helixtrans-68.8-45.9-178.600000111.6N379 Q384 A385N379-A381 VanDerWaalsContact C-N 3.34Å; N379-A381 PolarHBondContact O-N 3.13Å; N379-A381 PolarHBondContact OD1-N 3.39Å; A381-Q384 PolarHBondContact O-N 3.3Å; A381-A385 PolarHBondContact O-N 2.91Å; A381-A385 VanDerWaalsContact O-N 3.07Å
382T90.2Very high88.6Confident4 Ų431.8 Ų31.83%0.02519%0.185CC..Hα-helixtrans-66.9-43.1177.9-54.20000110.8C377 N379 Q384 A385 L386 L406 D410C377-T382 HydrophobicContact CB-CG2 3.97Å; C377-T382 WeakPolarHBondContact O-CB 3.33Å; N379-T382 WeakPolarHBondContact ND2-CB 3.3Å; N379-T382 PolarHBondContact ND2-OG1 3.03Å; N379-T382 PolarHBondContact O-N 3.04Å; N379-T382 PolarHBondContact OD1-N 3.38Å; N379-T382 PolarHBondContact OD1-OG1 3.01Å; T382-Q384 VanDerWaalsContact C-N 3.29Å; T382-Q384 PolarHBondContact O-N 3.03Å; T382-A385 PolarHBondContact O-N 2.84Å; T382-A385 VanDerWaalsContact O-N 3.13Å; T382-L386 HydrophobicContact CG2-CD1 4.32Å; T382-L386 HydrophobicContact CG2-CG 4.37Å; T382-L386 WeakPolarHBondContact O-CB 3.38Å; T382-L386 VanDerWaalsContact O-CG 3.26Å; T382-L386 WeakPolarHBondContact O-CG 3.4Å; T382-L386 PolarHBondContact O-N 2.8Å; T382-L406 HydrophobicContact CG2-CD2 3.97Å; T382-D410 HydrophobicContact CG2-CB 4.19Å; T382-D410 PolarHBondContact OG1-OD2 3.25Å
383L91.5Very high88.1Confident0 Ų030.7 Ų30.70%018%0.18CC..Hα-helixtrans-60.1-37.6175.1-75.5174.3000112.8L288 C378 N379 L386 E387 L454 A455 A458L288-L383 HydrophobicContact CD1-CD1 4.14Å; L288-L383 HydrophobicContact CD2-CD1 4.24Å; C378-L383 HydrophobicContact CB-CD1 4.31Å; C378-L383 WeakPolarHBondContact O-CD1 3.3Å; N379-L383 WeakPolarHBondContact O-CB 3.35Å; N379-L383 WeakPolarHBondContact O-CG 3.35Å; N379-L383 PolarHBondContact O-N 3.37Å; L383-L386 HydrophobicContact CD2-CD1 4.36Å; L383-L386 PolarHBondContact O-N 3.13Å; L383-E387 WeakPolarHBondContact O-CB 3.36Å; L383-E387 PolarHBondContact O-N 2.85Å; L383-L454 HydrophobicContact CD1-CB 4.27Å; L383-L454 HydrophobicContact CD2-CB 3.82Å; L383-A455 HydrophobicContact CB-CB 4.47Å; L383-A458 HydrophobicContact CB-CB 4.41Å; L383-A458 HydrophobicContact CD1-CB 3.67Å
384Q89.4Confident87.3Confident129 Ų12930.5 Ų30.560%0.60318%0.179SC*.Hα-helixtrans-65.5-42.3174.7-172.6177.425.400111.8P380 A381 T382 E387 L388P380-Q384 WeakPolarHBondContact O-CB 3.36Å; P380-Q384 PolarHBondContact O-N 2.94Å; A381-Q384 PolarHBondContact O-N 3.3Å; T382-Q384 VanDerWaalsContact C-N 3.29Å; T382-Q384 PolarHBondContact O-N 3.03Å; Q384-E387 PolarHBondContact O-N 3.4Å; Q384-L388 WeakPolarHBondContact O-CG 3.34Å; Q384-L388 PolarHBondContact O-N 3.39Å; Q384-L388 VanDerWaalsContact O-N 3.12Å
385A90.5Very high86.2Confident8 Ų832.9 Ų32.97%0.06620%0.204CC..Hα-helixtrans-63.5-42.6174.600000111.7A381 T382 L388 L389 A405 L406A381-A385 PolarHBondContact O-N 2.91Å; A381-A385 VanDerWaalsContact O-N 3.07Å; T382-A385 PolarHBondContact O-N 2.84Å; T382-A385 VanDerWaalsContact O-N 3.13Å; A385-L388 PolarHBondContact O-N 3.36Å; A385-L389 WeakPolarHBondContact O-CG 3.48Å; A385-L389 PolarHBondContact O-N 3.09Å; A385-A405 HydrophobicContact CB-CB 4.49Å; A385-L406 HydrophobicContact CB-CD2 3.66Å; A385-L406 HydrophobicContact CB-CG 4.04Å
386L91.6Very high84.5Confident2 Ų234.8 Ų34.81%0.0122%0.218CC..Hα-helixtrans-62.1-41.4175.3-68.7179.9000112.3L374 C377 T382 L383 L388 L389 V390 T414 F418 I451L374-L386 HydrophobicContact CD1-CD1 4.28Å; C377-L386 HydrophobicContact CB-CD1 4.13Å; T382-L386 HydrophobicContact CG2-CD1 4.32Å; T382-L386 HydrophobicContact CG2-CG 4.37Å; T382-L386 WeakPolarHBondContact O-CB 3.38Å; T382-L386 VanDerWaalsContact O-CG 3.26Å; T382-L386 WeakPolarHBondContact O-CG 3.4Å; T382-L386 PolarHBondContact O-N 2.8Å; L383-L386 HydrophobicContact CD2-CD1 4.36Å; L383-L386 PolarHBondContact O-N 3.13Å; L386-L388 VanDerWaalsContact C-N 3.32Å; L386-L388 PolarHBondContact O-N 3.48Å; L386-L389 HydrophobicContact CD2-CD1 4.26Å; L386-L389 WeakPolarHBondContact O-CB 3.42Å; L386-L389 PolarHBondContact O-N 2.99Å; L386-V390 WeakPolarHBondContact O-CG2 3.44Å; L386-V390 PolarHBondContact O-N 3.13Å; L386-T414 HydrophobicContact CD2-CG2 3.26Å; L386-F418 HydrophobicContact CD2-CE1 4Å; L386-F418 HydrophobicContact CD2-CZ 4.25Å; L386-I451 HydrophobicContact CB-CD1 4.35Å; L386-I451 HydrophobicContact CB-CG2 3.64Å
387E89.9Confident83.1Confident52 Ų5237.2 Ų37.224%0.24322%0.219CC..Hα-helixtrans-61.2-43175.8-174.2-178-170.300111.2L383 Q384 L389 V390 Q391 A455L383-E387 WeakPolarHBondContact O-CB 3.36Å; L383-E387 PolarHBondContact O-N 2.85Å; Q384-E387 PolarHBondContact O-N 3.4Å; E387-L389 VanDerWaalsContact C-N 3.32Å; E387-L389 PolarHBondContact O-N 3.27Å; E387-V390 WeakPolarHBondContact O-CB 3.43Å; E387-V390 PolarHBondContact O-N 2.89Å; E387-Q391 WeakPolarHBondContact O-CG 3.39Å; E387-Q391 PolarHBondContact O-N 3.35Å; E387-A455 HydrophobicContact CB-CB 3.93Å; E387-A455 HydrophobicContact CG-CB 4.27Å
388L88.6Confident81.5Confident45 Ų4546.8 Ų46.824%0.23626%0.264CS..Hα-helixtrans-63.3-38.6175.4-69.5171.4000111.4Q384 A385 L386 V390 Q391 C392 L401Q384-L388 WeakPolarHBondContact O-CG 3.34Å; Q384-L388 PolarHBondContact O-N 3.39Å; Q384-L388 VanDerWaalsContact O-N 3.12Å; A385-L388 PolarHBondContact O-N 3.36Å; L386-L388 VanDerWaalsContact C-N 3.32Å; L386-L388 PolarHBondContact O-N 3.48Å; L388-V390 VanDerWaalsContact C-N 3.34Å; L388-V390 PolarHBondContact O-N 2.87Å; L388-Q391 WeakPolarHBondContact O-CB 3.45Å; L388-Q391 PolarHBondContact O-N 3.42Å; L388-C392 PolarHBondContact O-N 3.06Å; L388-C392 PolarHBondContact O-SG 3.07Å; L388-L401 HydrophobicContact CB-CD1 3.59Å; L388-L401 HydrophobicContact CB-CD2 3.76Å; L388-L401 HydrophobicContact CB-CG 3.96Å; L388-L401 HydrophobicContact CD1-CD2 3.74Å; L388-L401 HydrophobicContact CG-CD2 4.4Å
389L88.4Confident80Confident0 Ų048.6 Ų48.60%027%0.274CS..Hα-helixtrans-63-40.9174.9-73.8174.6000111.5A385 L386 E387 Q391 C392 A393 L401 L406 T414 F418 L425 L432 V434A385-L389 WeakPolarHBondContact O-CG 3.48Å; A385-L389 PolarHBondContact O-N 3.09Å; L386-L389 HydrophobicContact CD2-CD1 4.26Å; L386-L389 WeakPolarHBondContact O-CB 3.42Å; L386-L389 PolarHBondContact O-N 2.99Å; E387-L389 VanDerWaalsContact C-N 3.32Å; E387-L389 PolarHBondContact O-N 3.27Å; L389-Q391 VanDerWaalsContact C-N 3.34Å; L389-C392 WeakPolarHBondContact O-CB 3.46Å; L389-C392 PolarHBondContact O-N 3.03Å; L389-A393 WeakPolarHBondContact O-CB 3.35Å; L389-A393 PolarHBondContact O-N 3.04Å; L389-L401 HydrophobicContact CB-CD1 4.13Å; L389-L401 HydrophobicContact CD2-CB 4.45Å; L389-L401 HydrophobicContact CD2-CD1 3.31Å; L389-L401 HydrophobicContact CG-CD1 3.46Å; L389-L401 VanDerWaalsContact CG-CD1 3.46Å; L389-L401 VanDerWaalsContact N-CD1 3.33Å; L389-L406 HydrophobicContact CD1-CD1 3.71Å; L389-T414 HydrophobicContact CD1-CG2 4.11Å; L389-F418 HydrophobicContact CB-CE2 4.13Å; L389-F418 HydrophobicContact CB-CZ 4.05Å; L389-F418 HydrophobicContact CD1-CE2 4.22Å; L389-F418 HydrophobicContact CD1-CZ 4.09Å; L389-L425 HydrophobicContact CD1-CD1 4.15Å; L389-L425 HydrophobicContact CD2-CD1 3.94Å; L389-L432 HydrophobicContact CD2-CB 3.87Å; L389-L432 HydrophobicContact CD2-CD1 4.13Å; L389-V434 HydrophobicContact CB-CG2 3.95Å; L389-V434 HydrophobicContact CD2-CG2 3.39Å; L389-V434 HydrophobicContact CG-CG2 4.17Å
390V87.1Confident78.8Confident5 Ų550.4 Ų50.43%0.0329%0.288CS..Hα-helixtrans-63.3-39.5174.31650000111.6L266 L386 E387 L388 C392 A393 S394 C448 I451L266-V390 HydrophobicContact CD1-CG1 4.33Å; L386-V390 WeakPolarHBondContact O-CG2 3.44Å; L386-V390 PolarHBondContact O-N 3.13Å; E387-V390 WeakPolarHBondContact O-CB 3.43Å; E387-V390 PolarHBondContact O-N 2.89Å; L388-V390 VanDerWaalsContact C-N 3.34Å; L388-V390 PolarHBondContact O-N 2.87Å; V390-C392 VanDerWaalsContact C-N 3.32Å; V390-C392 PolarHBondContact O-N 3.34Å; V390-A393 PolarHBondContact O-N 3.3Å; V390-S394 WeakPolarHBondContact O-CB 3.45Å; V390-S394 PolarHBondContact O-N 2.79Å; V390-S394 PolarHBondContact O-OG 3.24Å; V390-C448 HydrophobicContact CG1-CB 3.62Å; V390-C448 HydrophobicContact CG2-CB 4.37Å; V390-I451 HydrophobicContact CG2-CB 3.99Å; V390-I451 HydrophobicContact CG2-CD1 3.78Å; V390-I451 HydrophobicContact CG2-CG1 4.49Å; V390-I451 HydrophobicContact CG2-CG2 3.83Å
391Q83.9Confident78.3Confident47 Ų4748.2 Ų48.222%0.2227%0.273CS..Hα-helixtrans-62.8-39.2174.9-71.8175.39.500111.9E387 L388 L389 S394 G395 S396 R397E387-Q391 WeakPolarHBondContact O-CG 3.39Å; E387-Q391 PolarHBondContact O-N 3.35Å; L388-Q391 WeakPolarHBondContact O-CB 3.45Å; L388-Q391 PolarHBondContact O-N 3.42Å; L389-Q391 VanDerWaalsContact C-N 3.34Å; Q391-S394 WeakPolarHBondContact CA-OG 3.2Å; Q391-S394 PolarHBondContact O-OG 3.09Å; Q391-S394 VanDerWaalsContact O-OG 3.08Å; Q391-G395 PolarHBondContact O-N 3.26Å; Q391-S396 WeakPolarHBondContact CA-OG 3.22Å; Q391-S396 VanDerWaalsContact CB-OG 3.32Å; Q391-S396 WeakPolarHBondContact CB-OG 3.38Å; Q391-S396 PolarHBondContact O-N 3.49Å; Q391-S396 VanDerWaalsContact O-N 3.15Å; Q391-S396 PolarHBondContact O-OG 3.39Å; Q391-R397 HydrophobicContact CB-CB 4.49Å
392C80.9Confident77.7Confident31 Ų3147.6 Ų47.621%0.20927%0.265CS..Hα-helixtrans-65.3-48.2174.3-59.30000111.3L388 L389 V390 S394 G395 T399L388-C392 PolarHBondContact O-N 3.06Å; L388-C392 PolarHBondContact O-SG 3.07Å; L389-C392 WeakPolarHBondContact O-CB 3.46Å; L389-C392 PolarHBondContact O-N 3.03Å; V390-C392 VanDerWaalsContact C-N 3.32Å; V390-C392 PolarHBondContact O-N 3.34Å; C392-S394 VanDerWaalsContact C-N 3.27Å; C392-S394 PolarHBondContact O-N 2.93Å; C392-G395 PolarHBondContact O-N 3.03Å; C392-G395 VanDerWaalsContact O-N 3.13Å; C392-T399 PolarHBondContact SG-O 2.96Å
393A77.6Confident76.7Confident22 Ų2248.1 Ų48.118%0.18227%0.268CS..Hα-helixtrans-63.7-32.3-177.800000113.2L389 V390 G395 V434 I436L389-A393 WeakPolarHBondContact O-CB 3.35Å; L389-A393 PolarHBondContact O-N 3.04Å; V390-A393 PolarHBondContact O-N 3.3Å; A393-G395 VanDerWaalsContact C-N 3.32Å; A393-V434 HydrophobicContact CB-CB 4.07Å; A393-V434 HydrophobicContact CB-CG1 3.58Å; A393-I436 HydrophobicContact CB-CD1 4.24Å; A393-I436 HydrophobicContact CB-CG1 4.22Å; A393-I436 WeakPolarHBondContact O-CD1 3.2Å
394S72.3Confident75.7Confident5 Ų553.7 Ų53.74%0.03530%0.302CS..THydrogen-bonded Turntrans-82.1-5.5178.354.40000113.8Q263 V390 Q391 C392 S396Q263-S394 WeakPolarHBondContact CB-O 3.31Å; V390-S394 WeakPolarHBondContact O-CB 3.45Å; V390-S394 PolarHBondContact O-N 2.79Å; V390-S394 PolarHBondContact O-OG 3.24Å; Q391-S394 WeakPolarHBondContact CA-OG 3.2Å; Q391-S394 PolarHBondContact O-OG 3.09Å; Q391-S394 VanDerWaalsContact O-OG 3.08Å; C392-S394 VanDerWaalsContact C-N 3.27Å; C392-S394 PolarHBondContact O-N 2.93Å; S394-S396 PolarHBondContact O-N 3.3Å; S394-S396 PolarHBondContact OG-OG 3.34Å
395G67.6Low75.1Confident52 Ų5249.3 Ų49.354%0.53629%0.289SS..THydrogen-bonded Turntrans73.89.8-176.600000114.2Q391 C392 A393 R397Q391-G395 PolarHBondContact O-N 3.26Å; C392-G395 PolarHBondContact O-N 3.03Å; C392-G395 VanDerWaalsContact O-N 3.13Å; A393-G395 VanDerWaalsContact C-N 3.32Å; G395-R397 VanDerWaalsContact C-N 3.26Å; G395-R397 PolarHBondContact O-N 3.42Å
396S57Low74.7Confident52 Ų5249 Ų4936%0.36429%0.286SS..SBendtrans-72.6-17.4177.8670000113.8Q391 S394Q391-S396 WeakPolarHBondContact CA-OG 3.22Å; Q391-S396 VanDerWaalsContact CB-OG 3.32Å; Q391-S396 WeakPolarHBondContact CB-OG 3.38Å; Q391-S396 PolarHBondContact O-N 3.49Å; Q391-S396 VanDerWaalsContact O-N 3.15Å; Q391-S396 PolarHBondContact O-OG 3.39Å; S394-S396 PolarHBondContact O-N 3.3Å; S394-S396 PolarHBondContact OG-OG 3.34Å
397R57.3Low74.2Confident123 Ų12352.7 Ų52.746%0.46431%0.31SS..  trans-148.4133.3-179-148.8173.7168.9-166.8-4.7110.5Q391 G395 T399Q391-R397 HydrophobicContact CB-CB 4.49Å; G395-R397 VanDerWaalsContact C-N 3.26Å; G395-R397 PolarHBondContact O-N 3.42Å; R397-T399 WeakPolarHBondContact CD-OG1 3.5Å; R397-T399 HydrophobicContact CG-CG2 3.84Å; R397-T399 WeakPolarHBondContact CG-OG1 3.26Å; R397-T399 VanDerWaalsContact NE-CG2 3.26Å; R397-T399 PolarHBondContact NE-OG1 3.3Å; R397-T399 PolarHBondContact O-N 2.96Å
398E55.1Low73.7Confident201 Ų20155 Ų5594%0.93932%0.324SS*.  trans-77.45171.5-70.1-176.6164.200112.9T400E398-T400 PolarHBondContact O-N 3.31Å
399T56Low73.3Confident51 Ų5157.7 Ų57.731%0.31334%0.338SS..PPolyproline II helixtrans-78.1118.2-17248.60000112C392 R397C392-T399 PolarHBondContact SG-O 2.96Å; R397-T399 WeakPolarHBondContact CD-OG1 3.5Å; R397-T399 HydrophobicContact CG-CG2 3.84Å; R397-T399 WeakPolarHBondContact CG-OG1 3.26Å; R397-T399 VanDerWaalsContact NE-CG2 3.26Å; R397-T399 PolarHBondContact NE-OG1 3.3Å; R397-T399 PolarHBondContact O-N 2.96Å
400T64.8Low73.1Confident101 Ų10158.4 Ų58.462%0.6234%0.342SS*.PPolyproline II helixtrans-64.7126.4164.350.30000110.6E398 V431E398-T400 PolarHBondContact O-N 3.31Å; T400-V431 VanDerWaalsContact CB-CG1 3.49Å; T400-V431 HydrophobicContact CG2-CG1 3.62Å; T400-V431 HydrophobicContact CG2-CG2 4.34Å
401L77.3Confident73.1Confident16 Ų1659.1 Ų59.18%0.08434%0.344CS..EExtended strand (participates in β ladder)trans-81.2137.4172-93.9158.3000110.6L388 L389 A405 V431 L432L388-L401 HydrophobicContact CB-CD1 3.59Å; L388-L401 HydrophobicContact CB-CD2 3.76Å; L388-L401 HydrophobicContact CB-CG 3.96Å; L388-L401 HydrophobicContact CD1-CD2 3.74Å; L388-L401 HydrophobicContact CG-CD2 4.4Å; L389-L401 HydrophobicContact CB-CD1 4.13Å; L389-L401 HydrophobicContact CD2-CB 4.45Å; L389-L401 HydrophobicContact CD2-CD1 3.31Å; L389-L401 HydrophobicContact CG-CD1 3.46Å; L389-L401 VanDerWaalsContact CG-CD1 3.46Å; L389-L401 VanDerWaalsContact N-CD1 3.33Å; L401-A405 HydrophobicContact CD2-CB 4.09Å; L401-V431 CarbonylContact O-C 3.59Å; L401-V431 WeakPolarHBondContact O-CA 3.48Å; L401-L432 HydrophobicContact CB-CB 4.14Å; L401-L432 HydrophobicContact CB-CD1 4.47Å; L401-L432 PolarHBondContact O-N 2.99Å
402S75.6Confident73.2Confident54 Ų5459.9 Ų59.938%0.37835%0.348SS..EExtended strand (participates in β ladder)trans-63.3139.5173.2-177.50000110.7T404 A405 D430S402-T404 PolarHBondContact O-N 3.39Å; S402-T404 PolarHBondContact OG-N 3.28Å; S402-T404 PolarHBondContact OG-OG1 2.78Å; S402-A405 WeakPolarHBondContact O-CB 3.42Å; S402-A405 PolarHBondContact O-N 2.84Å; S402-D430 CarbonylContact C-O 3.56Å; S402-D430 VanDerWaalsContact CA-O 3.31Å; S402-D430 WeakPolarHBondContact CA-O 3.23Å
403S68.4Low73.5Confident15 Ų1560.6 Ų60.611%0.10535%0.346CS..G310 helixtrans-57.8-26.6172.9620000112.7A405 D430S403-A405 VanDerWaalsContact C-N 3.25Å; S403-A405 PolarHBondContact O-N 3.42Å; S403-D430 PolarHBondContact N-O 2.76Å; S403-D430 WeakPolarHBondContact OG-CA 3.45Å
404T70.7Confident74Confident116 Ų11659.6 Ų59.671%0.71234%0.338SS*.G310 helixtrans-74.4-9.6176.665.10000114.2S402 L406S402-T404 PolarHBondContact O-N 3.39Å; S402-T404 PolarHBondContact OG-N 3.28Å; S402-T404 PolarHBondContact OG-OG1 2.78Å; T404-L406 PolarHBondContact O-N 2.78Å
405A76.7Confident74.8Confident38 Ų3862.8 Ų62.831%0.31435%0.352SS..G310 helixtrans-72-20.1-179.900000112.7A385 L401 S402 S403A385-A405 HydrophobicContact CB-CB 4.49Å; L401-A405 HydrophobicContact CD2-CB 4.09Å; S402-A405 WeakPolarHBondContact O-CB 3.42Å; S402-A405 PolarHBondContact O-N 2.84Å; S403-A405 VanDerWaalsContact C-N 3.25Å; S403-A405 PolarHBondContact O-N 3.42Å
406L81.3Confident75.7Confident2 Ų263.1 Ų63.11%0.0134%0.34CS..SBendtrans-121.3116172.8-73175.1000109T382 A385 L389 T404 D410 T414 L432T382-L406 HydrophobicContact CG2-CD2 3.97Å; A385-L406 HydrophobicContact CB-CD2 3.66Å; A385-L406 HydrophobicContact CB-CG 4.04Å; L389-L406 HydrophobicContact CD1-CD1 3.71Å; T404-L406 PolarHBondContact O-N 2.78Å; L406-D410 HydrophobicContact CD2-CB 4.27Å; L406-T414 HydrophobicContact CD1-CG2 4.26Å; L406-L432 HydrophobicContact CB-CD1 4.44Å; L406-L432 HydrophobicContact CD1-CD1 3.87Å; L406-L432 HydrophobicContact CG-CD1 4.24Å
407P81.6Confident77.2Confident79 Ų7960.8 Ų60.851%0.51332%0.323SS..  trans-51.7153.5167.5-24.333.5000111.2D409 D410 Y411P407-D409 VanDerWaalsContact C-N 3.31Å; P407-D409 PolarHBondContact O-N 3.02Å; P407-D410 CarbonylContact O-C 3.56Å; P407-D410 WeakPolarHBondContact O-CA 3.29Å; P407-D410 PolarHBondContact O-N 3.26Å; P407-Y411 PolarHBondContact O-N 3.35Å
408D80.1Confident78.8Confident101 Ų10155.1 Ų55.154%0.5430%0.302SS..Hα-helixtrans-55.7-44.4-174.5-71.7-28.2000113D410 Y411 E412 R427D408-D410 VanDerWaalsContact C-N 3.27Å; D408-D410 PolarHBondContact O-N 3.26Å; D408-Y411 PolarHBondContact O-N 3.19Å; D408-E412 WeakPolarHBondContact O-CG 3.45Å; D408-E412 PolarHBondContact O-N 2.84Å; D408-R427 IonicContact OD1-CZ 3.15Å; D408-R427 IonicContact OD1-NH1 2.69Å; D408-R427 PolarHBondContact OD1-NH1 2.65Å; D408-R427 IonicContact OD1-NH2 2.7Å; D408-R427 PolarHBondContact OD1-NH2 2.78Å
409D80.1Confident80.3Confident100 Ų10047.8 Ų47.854%0.53528%0.276SS..Hα-helixtrans-58-37.9175.1-71.31.7000112.9P407 R413P407-D409 VanDerWaalsContact C-N 3.31Å; P407-D409 PolarHBondContact O-N 3.02Å; D409-R413 VanDerWaalsContact O-CG 3.3Å; D409-R413 WeakPolarHBondContact O-CG 3.44Å; D409-R413 PolarHBondContact O-N 2.84Å
410D84.1Confident81.7Confident15 Ų1547 Ų478%0.0827%0.273CS..Hα-helixtrans-80.4-31.2179.8-75-9.5000111.8T382 L406 P407 D408 R413 T414T382-D410 HydrophobicContact CG2-CB 4.19Å; T382-D410 PolarHBondContact OG1-OD2 3.25Å; L406-D410 HydrophobicContact CD2-CB 4.27Å; P407-D410 CarbonylContact O-C 3.56Å; P407-D410 WeakPolarHBondContact O-CA 3.29Å; P407-D410 PolarHBondContact O-N 3.26Å; D408-D410 VanDerWaalsContact C-N 3.27Å; D408-D410 PolarHBondContact O-N 3.26Å; D410-R413 IonicContact OD1-NH1 2.72Å; D410-R413 PolarHBondContact OD1-NH1 3.21Å; D410-T414 WeakPolarHBondContact O-CB 3.44Å; D410-T414 PolarHBondContact O-N 2.8Å; D410-T414 PolarHBondContact O-OG1 2.82Å
411Y86.9Confident82.8Confident21 Ų2142.2 Ų42.28%0.08224%0.243CC..Hα-helixtrans-62-49.3172.6175.5-85.8000110.4P407 D408 R413 T414 E415 L425 R427 L432P407-Y411 PolarHBondContact O-N 3.35Å; D408-Y411 PolarHBondContact O-N 3.19Å; Y411-R413 VanDerWaalsContact C-N 3.34Å; Y411-R413 PolarHBondContact O-N 2.78Å; Y411-T414 PolarHBondContact O-N 2.93Å; Y411-E415 HydrophobicContact CE1-CB 4.25Å; Y411-E415 VanDerWaalsContact O-CB 3.31Å; Y411-E415 WeakPolarHBondContact O-CB 3.34Å; Y411-E415 PolarHBondContact O-N 2.85Å; Y411-E415 PolarHBondContact OH-OE1 2.95Å; Y411-L425 HydrophobicContact CD2-CD2 3.83Å; Y411-L425 HydrophobicContact CD2-CG 4.42Å; Y411-L425 HydrophobicContact CE2-CD1 4.48Å; Y411-L425 HydrophobicContact CE2-CD2 3.59Å; Y411-L425 HydrophobicContact CE2-CG 3.71Å; Y411-R427 VanDerWaalsContact CB-NH2 3.35Å; Y411-R427 HydrophobicContact CE2-CB 3.89Å; Y411-R427 PolarHBondContact OH-N 2.71Å; Y411-L432 HydrophobicContact CD2-CD2 3.73Å; Y411-L432 HydrophobicContact CE2-CD2 3.57Å
412E85.9Confident83.3Confident62 Ų6242.9 Ų42.929%0.2925%0.247SC..Hα-helixtrans-62-42.1-179.1-66.2-175.6169.200111.4L99 D408 H416L99-E412 HydrophobicContact CD1-CB 3.61Å; L99-E412 HydrophobicContact CD2-CB 3.93Å; L99-E412 WeakPolarHBondContact CD2-OE2 3.18Å; L99-E412 HydrophobicContact CG-CB 3.85Å; L99-E412 WeakPolarHBondContact CG-OE2 3.36Å; D408-E412 WeakPolarHBondContact O-CG 3.45Å; D408-E412 PolarHBondContact O-N 2.84Å; E412-H416 PolarHBondContact O-N 2.84Å; E412-H416 VanDerWaalsContact O-N 3.09Å
413R87.3Confident83.8Confident46 Ų4640.6 Ų40.617%0.17423%0.23CC..Hα-helixtrans-63.4-44.2174.5-69.6173.5-165.8129.97.5112L99 V373 D409 D410 Y411 H416 V417L99-R413 HydrophobicContact CD1-CG 4.44Å; V373-R413 HydrophobicContact CG1-CB 3.77Å; V373-R413 HydrophobicContact CG1-CG 4.08Å; D409-R413 VanDerWaalsContact O-CG 3.3Å; D409-R413 WeakPolarHBondContact O-CG 3.44Å; D409-R413 PolarHBondContact O-N 2.84Å; D410-R413 IonicContact OD1-NH1 2.72Å; D410-R413 PolarHBondContact OD1-NH1 3.21Å; Y411-R413 VanDerWaalsContact C-N 3.34Å; Y411-R413 PolarHBondContact O-N 2.78Å; R413-H416 PolarHBondContact O-N 3.17Å; R413-V417 WeakPolarHBondContact O-CG2 3.36Å; R413-V417 PolarHBondContact O-N 3.28Å
414T88.8Confident84.7Confident1 Ų140.6 Ų40.61%0.00623%0.23CC..Hα-helixtrans-64.1-44.8179.2-59.40000111L386 L389 L406 D410 Y411 H416 V417 F418 L425L386-T414 HydrophobicContact CD2-CG2 3.26Å; L389-T414 HydrophobicContact CD1-CG2 4.11Å; L406-T414 HydrophobicContact CD1-CG2 4.26Å; D410-T414 WeakPolarHBondContact O-CB 3.44Å; D410-T414 PolarHBondContact O-N 2.8Å; D410-T414 PolarHBondContact O-OG1 2.82Å; Y411-T414 PolarHBondContact O-N 2.93Å; T414-H416 VanDerWaalsContact C-N 3.28Å; T414-H416 PolarHBondContact O-N 2.77Å; T414-V417 PolarHBondContact O-N 3.01Å; T414-F418 HydrophobicContact CG2-CD1 3.68Å; T414-F418 HydrophobicContact CG2-CE1 3.52Å; T414-F418 HydrophobicContact CG2-CE2 4.44Å; T414-F418 HydrophobicContact CG2-CG 4.24Å; T414-F418 HydrophobicContact CG2-CZ 3.94Å; T414-F418 VanDerWaalsContact O-CB 3.31Å; T414-F418 WeakPolarHBondContact O-CB 3.36Å; T414-F418 WeakPolarHBondContact O-CD1 3.44Å; T414-F418 WeakPolarHBondContact O-CG 3.38Å; T414-F418 PolarHBondContact O-N 3.4Å; T414-L425 HydrophobicContact CG2-CD2 3.73Å
415E88.3Confident85.5Confident72 Ų7235.3 Ų35.334%0.33620%0.198SC..Hα-helixtrans-58.7-42.7177.8-174.5176.3-115.700110.8Y411 F418 A419 L425Y411-E415 HydrophobicContact CE1-CB 4.25Å; Y411-E415 VanDerWaalsContact O-CB 3.31Å; Y411-E415 WeakPolarHBondContact O-CB 3.34Å; Y411-E415 PolarHBondContact O-N 2.85Å; Y411-E415 PolarHBondContact OH-OE1 2.95Å; E415-F418 PolarHBondContact O-N 3.42Å; E415-A419 VanDerWaalsContact O-CB 3.22Å; E415-A419 WeakPolarHBondContact O-CB 3.32Å; E415-A419 PolarHBondContact O-N 3.37Å; E415-L425 HydrophobicContact CB-CB 4.49Å; E415-L425 HydrophobicContact CB-CD2 4.28Å; E415-L425 HydrophobicContact CG-CB 4.49Å
416H86Confident85.9Confident60 Ų6040.4 Ų40.428%0.27821%0.209SC..Hα-helixtrans-61.1-52174.7-177.771.2000112.5E412 R413 T414 F418 A419 S420E412-H416 PolarHBondContact O-N 2.84Å; E412-H416 VanDerWaalsContact O-N 3.09Å; R413-H416 PolarHBondContact O-N 3.17Å; T414-H416 VanDerWaalsContact C-N 3.28Å; T414-H416 PolarHBondContact O-N 2.77Å; H416-F418 VanDerWaalsContact C-N 3.3Å; H416-F418 PolarHBondContact O-N 3.2Å; H416-A419 PolarHBondContact O-N 2.97Å; H416-S420 PolarHBondContact O-N 3Å; H416-S420 PolarHBondContact O-OG 2.79Å
417V89.6Confident86.1Confident3 Ų344.3 Ų44.32%0.01822%0.224CC..Hα-helixtrans-59.3-42.3178.9171.70000111.4V373 L374 R413 T414 C421 L447V373-V417 HydrophobicContact CB-CG2 3.88Å; V373-V417 HydrophobicContact CG1-CG2 3.66Å; L374-V417 HydrophobicContact CB-CG2 4.39Å; R413-V417 WeakPolarHBondContact O-CG2 3.36Å; R413-V417 PolarHBondContact O-N 3.28Å; T414-V417 PolarHBondContact O-N 3.01Å; V417-C421 PolarHBondContact O-N 2.69Å; V417-C421 PolarHBondContact O-SG 2.65Å; V417-C421 VanDerWaalsContact O-SG 3.35Å; V417-L447 HydrophobicContact CG1-CD1 3.66Å
418F90.4Very high86Confident3 Ų343.8 Ų43.81%0.01322%0.216CC..Hα-helixtrans-65.7-47.2179.8-8338.7000110.2L386 L389 T414 E415 H416 S420 C421 N422 V423 L425 V434 L447 I451L386-F418 HydrophobicContact CD2-CE1 4Å; L386-F418 HydrophobicContact CD2-CZ 4.25Å; L389-F418 HydrophobicContact CB-CE2 4.13Å; L389-F418 HydrophobicContact CB-CZ 4.05Å; L389-F418 HydrophobicContact CD1-CE2 4.22Å; L389-F418 HydrophobicContact CD1-CZ 4.09Å; T414-F418 HydrophobicContact CG2-CD1 3.68Å; T414-F418 HydrophobicContact CG2-CE1 3.52Å; T414-F418 HydrophobicContact CG2-CE2 4.44Å; T414-F418 HydrophobicContact CG2-CG 4.24Å; T414-F418 HydrophobicContact CG2-CZ 3.94Å; T414-F418 VanDerWaalsContact O-CB 3.31Å; T414-F418 WeakPolarHBondContact O-CB 3.36Å; T414-F418 WeakPolarHBondContact O-CD1 3.44Å; T414-F418 WeakPolarHBondContact O-CG 3.38Å; T414-F418 PolarHBondContact O-N 3.4Å; E415-F418 PolarHBondContact O-N 3.42Å; H416-F418 VanDerWaalsContact C-N 3.3Å; H416-F418 PolarHBondContact O-N 3.2Å; F418-S420 VanDerWaalsContact C-N 3.34Å; F418-S420 PolarHBondContact O-N 3.09Å; F418-C421 CarbonylContact O-C 3.57Å; F418-C421 WeakPolarHBondContact O-CA 3.29Å; F418-C421 PolarHBondContact O-N 2.81Å; F418-N422 PolarHBondContact O-N 2.88Å; F418-V423 CarbonylContact C-O 3.54Å; F418-V423 HydrophobicContact CB-CB 3.97Å; F418-V423 HydrophobicContact CB-CG1 4.24Å; F418-V423 WeakPolarHBondContact CB-O 3.15Å; F418-V423 HydrophobicContact CD2-CB 4.11Å; F418-V423 HydrophobicContact CD2-CG1 3.5Å; F418-V423 HydrophobicContact CE2-CG1 4.17Å; F418-V423 HydrophobicContact CG-CB 4.26Å; F418-V423 HydrophobicContact CG-CG1 4.15Å; F418-V423 CarbonylContact O-C 3.59Å; F418-V423 WeakPolarHBondContact O-CA 3.47Å; F418-V423 WeakPolarHBondContact O-CB 3.26Å; F418-V423 PolarHBondContact O-N 3.3Å; F418-L425 HydrophobicContact CD2-CB 4.13Å; F418-V434 HydrophobicContact CD2-CG1 4.01Å; F418-V434 HydrophobicContact CE2-CG1 3.85Å; F418-V434 HydrophobicContact CE2-CG2 4.13Å; F418-L447 HydrophobicContact CD1-CD2 3.75Å; F418-L447 HydrophobicContact CE1-CD2 4.05Å; F418-L447 HydrophobicContact CG-CD2 4.2Å; F418-I451 HydrophobicContact CE1-CD1 3.74Å; F418-I451 HydrophobicContact CZ-CD1 4.14Å
419A87.3Confident85.9Confident48 Ų4844.1 Ų44.140%0.39723%0.227SC..Hα-helixtrans-59.6-43.3-17900000112E415 H416 C421 N422 V423E415-A419 VanDerWaalsContact O-CB 3.22Å; E415-A419 WeakPolarHBondContact O-CB 3.32Å; E415-A419 PolarHBondContact O-N 3.37Å; H416-A419 PolarHBondContact O-N 2.97Å; A419-C421 PolarHBondContact O-N 3.14Å; A419-N422 PolarHBondContact O-N 3.31Å; A419-N422 VanDerWaalsContact O-N 3.17Å; A419-V423 WeakPolarHBondContact CA-O 3.46Å; A419-V423 PolarHBondContact N-O 2.62Å; A419-V423 VanDerWaalsContact N-O 3.13Å
420S85Confident85.9Confident35 Ų3545.1 Ų45.125%0.24523%0.232CC..Hα-helixtrans-65.8-18.1176.3-69.90000113.6D369 C370 H416 F418D369-S420 PolarHBondContact OD2-OG 3.33Å; C370-S420 WeakPolarHBondContact SG-CB 3.25Å; H416-S420 PolarHBondContact O-N 3Å; H416-S420 PolarHBondContact O-OG 2.79Å; F418-S420 VanDerWaalsContact C-N 3.34Å; F418-S420 PolarHBondContact O-N 3.09Å
421C87.8Confident85.8Confident0 Ų046.1 Ų46.10%024%0.239CC..THydrogen-bonded Turntrans-104.619.3176.1-62.20000113.5V417 F418 A419 V423 P444 L447V417-C421 PolarHBondContact O-N 2.69Å; V417-C421 PolarHBondContact O-SG 2.65Å; V417-C421 VanDerWaalsContact O-SG 3.35Å; F418-C421 CarbonylContact O-C 3.57Å; F418-C421 WeakPolarHBondContact O-CA 3.29Å; F418-C421 PolarHBondContact O-N 2.81Å; A419-C421 PolarHBondContact O-N 3.14Å; C421-V423 VanDerWaalsContact C-N 3.27Å; C421-V423 PolarHBondContact O-N 3.45Å; C421-P444 VanDerWaalsContact O-CD 3.29Å; C421-P444 WeakPolarHBondContact O-CD 3.37Å; C421-P444 WeakPolarHBondContact O-CG 3.31Å; C421-L447 HydrophobicContact CB-CB 3.98Å; C421-L447 HydrophobicContact CB-CD2 3.68Å; C421-L447 HydrophobicContact CB-CG 4.34Å
422N86.7Confident85.7Confident30 Ų3045.4 Ų45.416%0.1624%0.236CC..THydrogen-bonded Turntrans60.933.2-178.2-62.6-15.9000114F418 A419 K437 E439 P444F418-N422 PolarHBondContact O-N 2.88Å; A419-N422 PolarHBondContact O-N 3.31Å; A419-N422 VanDerWaalsContact O-N 3.17Å; N422-K437 HydrophobicContact CB-CB 4.46Å; N422-K437 WeakPolarHBondContact O-CB 3.33Å; N422-K437 PolarHBondContact O-N 2.87Å; N422-E439 VanDerWaalsContact CG-OE2 3.31Å; N422-E439 PolarHBondContact ND2-OE2 3.21Å; N422-E439 VanDerWaalsContact ND2-OE2 3.09Å; N422-E439 PolarHBondContact OD1-OE2 3.4Å; N422-P444 HydrophobicContact CB-CG 4.26Å
423V87.4Confident85.5Confident5 Ų549.7 Ų49.73%0.0325%0.25CC..EExtended strand (participates in β ladder)trans-117127.4172.6-174.50000108.1F418 A419 C421 V434 I436 P444 L447F418-V423 CarbonylContact C-O 3.54Å; F418-V423 HydrophobicContact CB-CB 3.97Å; F418-V423 HydrophobicContact CB-CG1 4.24Å; F418-V423 WeakPolarHBondContact CB-O 3.15Å; F418-V423 HydrophobicContact CD2-CB 4.11Å; F418-V423 HydrophobicContact CD2-CG1 3.5Å; F418-V423 HydrophobicContact CE2-CG1 4.17Å; F418-V423 HydrophobicContact CG-CB 4.26Å; F418-V423 HydrophobicContact CG-CG1 4.15Å; F418-V423 CarbonylContact O-C 3.59Å; F418-V423 WeakPolarHBondContact O-CA 3.47Å; F418-V423 WeakPolarHBondContact O-CB 3.26Å; F418-V423 PolarHBondContact O-N 3.3Å; A419-V423 WeakPolarHBondContact CA-O 3.46Å; A419-V423 PolarHBondContact N-O 2.62Å; A419-V423 VanDerWaalsContact N-O 3.13Å; C421-V423 VanDerWaalsContact C-N 3.27Å; C421-V423 PolarHBondContact O-N 3.45Å; V423-V434 HydrophobicContact CG1-CG1 3.24Å; V423-I436 HydrophobicContact CG2-CG1 4.42Å; V423-P444 HydrophobicContact CG2-CB 3.87Å; V423-P444 HydrophobicContact CG2-CG 4.26Å; V423-L447 HydrophobicContact CG2-CD2 4.28Å
424S86Confident85.5Confident15 Ų1548.6 Ų48.611%0.10525%0.248CC..EExtended strand (participates in β ladder)trans-92.3127.1170.338.30000110.4V434 E435S424-V434 WeakPolarHBondContact O-CA 3.09Å; S424-E435 PolarHBondContact N-O 2.81Å; S424-E435 PolarHBondContact O-N 3.31Å; S424-E435 PolarHBondContact OG-O 3.34Å; S424-E435 VanDerWaalsContact OG-O 3.09Å
425L88.3Confident85.2Confident6 Ų654.2 Ų54.23%0.03127%0.274CS..EExtended strand (participates in β ladder)trans-99.5133.7163.8-178.764.2000107.9L389 Y411 T414 E415 F418 L432 R433 V434L389-L425 HydrophobicContact CD1-CD1 4.15Å; L389-L425 HydrophobicContact CD2-CD1 3.94Å; Y411-L425 HydrophobicContact CD2-CD2 3.83Å; Y411-L425 HydrophobicContact CD2-CG 4.42Å; Y411-L425 HydrophobicContact CE2-CD1 4.48Å; Y411-L425 HydrophobicContact CE2-CD2 3.59Å; Y411-L425 HydrophobicContact CE2-CG 3.71Å; T414-L425 HydrophobicContact CG2-CD2 3.73Å; E415-L425 HydrophobicContact CB-CB 4.49Å; E415-L425 HydrophobicContact CB-CD2 4.28Å; E415-L425 HydrophobicContact CG-CB 4.49Å; F418-L425 HydrophobicContact CD2-CB 4.13Å; L425-L432 HydrophobicContact CD1-CB 4.3Å; L425-R433 CarbonylContact C-O 3.49Å; L425-R433 WeakPolarHBondContact CA-O 2.99Å; L425-V434 HydrophobicContact CD1-CG2 3.85Å
426R85.6Confident84.9Confident144 Ų14452.2 Ų52.254%0.54327%0.266SS..EExtended strand (participates in β ladder)trans-133.6143.4173.5-63.7-173.9-172.1170.48.9110.1L432 R433R426-L432 WeakPolarHBondContact O-CA 3.44Å; R426-R433 PolarHBondContact N-O 2.83Å; R426-R433 PolarHBondContact O-N 3.01Å
427R84Confident84.5Confident84 Ų8453.8 Ų53.832%0.31727%0.272SS..EExtended strand (participates in β ladder)trans-100.9102.3171.3-170.5-179.7-76.3177.8-12.4109.2D408 Y411 L432D408-R427 IonicContact OD1-CZ 3.15Å; D408-R427 IonicContact OD1-NH1 2.69Å; D408-R427 PolarHBondContact OD1-NH1 2.65Å; D408-R427 IonicContact OD1-NH2 2.7Å; D408-R427 PolarHBondContact OD1-NH2 2.78Å; Y411-R427 VanDerWaalsContact CB-NH2 3.35Å; Y411-R427 HydrophobicContact CE2-CB 3.89Å; Y411-R427 PolarHBondContact OH-N 2.71Å; R427-L432 HydrophobicContact CB-CD2 4.18Å; R427-L432 HydrophobicContact CG-CD2 4.17Å
428D80.3Confident83.2Confident68 Ų6860.5 Ų60.536%0.36430%0.303SS..EExtended strand (participates in β ladder)trans-98.490.7175.5-75.6-12.4000108.7D430 V431 R433D428-D430 PolarHBondContact O-N 2.76Å; D428-V431 PolarHBondContact N-O 2.85Å; D428-V431 PolarHBondContact O-N 3.26Å; D428-R433 WeakPolarHBondContact OD2-CD 3.06Å; D428-R433 IonicContact OD2-CZ 3.14Å; D428-R433 IonicContact OD2-NE 2.67Å; D428-R433 PolarHBondContact OD2-NE 3.05Å; D428-R433 IonicContact OD2-NH1 3.21Å
429S78.5Confident81.8Confident108 Ų10866 Ų6676%0.75533%0.328SS*.THydrogen-bonded Turntrans56.4-107.2-175-55.60000111.9
430D79.3Confident80.4Confident122 Ų12272 Ų7265%0.65235%0.348SS*.THydrogen-bonded Turntrans-94.24.4-178.1-65.8-27.2000113.2S402 S403 D428S402-D430 CarbonylContact C-O 3.56Å; S402-D430 VanDerWaalsContact CA-O 3.31Å; S402-D430 WeakPolarHBondContact CA-O 3.23Å; S403-D430 PolarHBondContact N-O 2.76Å; S403-D430 WeakPolarHBondContact OG-CA 3.45Å; D428-D430 PolarHBondContact O-N 2.76Å
431V82.6Confident79.7Confident35 Ų3572.7 Ų72.721%0.21236%0.361CS..EExtended strand (participates in β ladder)trans-122.9134-174.11740000111.8T400 L401 D428 R433T400-V431 VanDerWaalsContact CB-CG1 3.49Å; T400-V431 HydrophobicContact CG2-CG1 3.62Å; T400-V431 HydrophobicContact CG2-CG2 4.34Å; L401-V431 CarbonylContact O-C 3.59Å; L401-V431 WeakPolarHBondContact O-CA 3.48Å; D428-V431 PolarHBondContact N-O 2.85Å; D428-V431 PolarHBondContact O-N 3.26Å; V431-R433 HydrophobicContact CG1-CG 4.18Å
432L84.4Confident79.4Confident7 Ų776 Ų764%0.03738%0.378CS..EExtended strand (participates in β ladder)trans-85.6127.8166.1-60.6179.6000110.1L389 L401 L406 Y411 L425 R426 R427L389-L432 HydrophobicContact CD2-CB 3.87Å; L389-L432 HydrophobicContact CD2-CD1 4.13Å; L401-L432 HydrophobicContact CB-CB 4.14Å; L401-L432 HydrophobicContact CB-CD1 4.47Å; L401-L432 PolarHBondContact O-N 2.99Å; L406-L432 HydrophobicContact CB-CD1 4.44Å; L406-L432 HydrophobicContact CD1-CD1 3.87Å; L406-L432 HydrophobicContact CG-CD1 4.24Å; Y411-L432 HydrophobicContact CD2-CD2 3.73Å; Y411-L432 HydrophobicContact CE2-CD2 3.57Å; L425-L432 HydrophobicContact CD1-CB 4.3Å; R426-L432 WeakPolarHBondContact O-CA 3.44Å; R427-L432 HydrophobicContact CB-CD2 4.18Å; R427-L432 HydrophobicContact CG-CD2 4.17Å
433R82.3Confident79.5Confident152 Ų15277.4 Ų77.457%0.57438%0.382SS*.EExtended strand (participates in β ladder)trans-114.5134.5174.3-63.1-162.2-174.8-172.20.9110.4L425 R426 D428 V431L425-R433 CarbonylContact C-O 3.49Å; L425-R433 WeakPolarHBondContact CA-O 2.99Å; R426-R433 PolarHBondContact N-O 2.83Å; R426-R433 PolarHBondContact O-N 3.01Å; D428-R433 WeakPolarHBondContact OD2-CD 3.06Å; D428-R433 IonicContact OD2-CZ 3.14Å; D428-R433 IonicContact OD2-NE 2.67Å; D428-R433 PolarHBondContact OD2-NE 3.05Å; D428-R433 IonicContact OD2-NH1 3.21Å; V431-R433 HydrophobicContact CG1-CG 4.18Å
434V86.1Confident79.6Confident23 Ų2377.8 Ų77.814%0.13939%0.385CS..EExtended strand (participates in β ladder)trans-119.2128.4176.9-169.50000108.7L389 A393 F418 V423 S424 L425L389-V434 HydrophobicContact CB-CG2 3.95Å; L389-V434 HydrophobicContact CD2-CG2 3.39Å; L389-V434 HydrophobicContact CG-CG2 4.17Å; A393-V434 HydrophobicContact CB-CB 4.07Å; A393-V434 HydrophobicContact CB-CG1 3.58Å; F418-V434 HydrophobicContact CD2-CG1 4.01Å; F418-V434 HydrophobicContact CE2-CG1 3.85Å; F418-V434 HydrophobicContact CE2-CG2 4.13Å; V423-V434 HydrophobicContact CG1-CG1 3.24Å; S424-V434 WeakPolarHBondContact O-CA 3.09Å; L425-V434 HydrophobicContact CD1-CG2 3.85Å
435E83.3Confident79.8Confident118 Ų11877.7 Ų77.755%0.55138%0.383SS*.EExtended strand (participates in β ladder)trans-130.9124.5178-179.8178.1-163.600108.9S424 K437S424-E435 PolarHBondContact N-O 2.81Å; S424-E435 PolarHBondContact O-N 3.31Å; S424-E435 PolarHBondContact OG-O 3.34Å; S424-E435 VanDerWaalsContact OG-O 3.09Å; E435-K437 PolarHBondContact O-N 2.99Å
436I82.3Confident80Confident31 Ų3177.7 Ų77.716%0.15938%0.382CS..EExtended strand (participates in β ladder)trans-79.7118.6174.8-62.4176.7000107.8A393 V423 H438 P444A393-I436 HydrophobicContact CB-CD1 4.24Å; A393-I436 HydrophobicContact CB-CG1 4.22Å; A393-I436 WeakPolarHBondContact O-CD1 3.2Å; V423-I436 HydrophobicContact CG2-CG1 4.42Å; I436-H438 PolarHBondContact O-N 3.38Å; I436-P444 HydrophobicContact CD1-CB 4.28Å; I436-P444 HydrophobicContact CG1-CB 4.33Å; I436-P444 HydrophobicContact CG2-CB 3.6Å; I436-P444 HydrophobicContact CG2-CG 3.63Å
437K76.4Confident80.4Confident93 Ų9370.9 Ų70.940%0.40436%0.357SS..  trans-72.6129.2174.7-60.9179.2-178173.80108.7N422 E435 E439N422-K437 HydrophobicContact CB-CB 4.46Å; N422-K437 WeakPolarHBondContact O-CB 3.33Å; N422-K437 PolarHBondContact O-N 2.87Å; E435-K437 PolarHBondContact O-N 2.99Å; K437-E439 HydrophobicContact CB-CG 4.48Å; K437-E439 PolarHBondContact O-N 2.89Å
438H63.6Low80.8Confident144 Ų14467.1 Ų67.167%0.66734%0.343SS*.  trans-77.973.9177.7-71.4-48.8000111.3I436I436-H438 PolarHBondContact O-N 3.38Å
439E60.9Low81.4Confident118 Ų11863.9 Ų63.955%0.55133%0.326SS*.  trans-107.2166171.8-68.9-175.5-168.900111.2N422 K437 G441N422-E439 VanDerWaalsContact CG-OE2 3.31Å; N422-E439 PolarHBondContact ND2-OE2 3.21Å; N422-E439 VanDerWaalsContact ND2-OE2 3.09Å; N422-E439 PolarHBondContact OD1-OE2 3.4Å; K437-E439 HydrophobicContact CB-CG 4.48Å; K437-E439 PolarHBondContact O-N 2.89Å; E439-G441 PolarHBondContact O-N 3.29Å
440Q57.9Low82.3Confident174 Ų17458.7 Ų58.781%0.81329%0.29SS*.SBendtrans-68.5128.9176.2-69.8-177.1-2.300110.3
441G69.4Low83Confident49 Ų4952.9 Ų52.951%0.50526%0.259SS..SBendtrans131.6169.4174.700000113.6E439E439-G441 PolarHBondContact O-N 3.29Å
442N83.1Confident83.5Confident70 Ų7052.9 Ų52.937%0.37426%0.256SS..SBendtrans-102.86.8179.8-65.7-36.5000112.9W44 L445 I446W44-N442 HydrophobicContact CB-CB 4.1Å; N442-L445 WeakPolarHBondContact O-CB 3.49Å; N442-L445 PolarHBondContact O-N 3.06Å; N442-I446 HydrophobicContact CB-CD1 3.88Å; N442-I446 HydrophobicContact CB-CG1 4.24Å; N442-I446 VanDerWaalsContact O-CG1 3.31Å; N442-I446 WeakPolarHBondContact O-CG1 3.46Å; N442-I446 PolarHBondContact O-N 3.29Å
443Y87.8Confident84.1Confident60 Ų6052.6 Ų52.624%0.23525%0.254CS..Hα-helixtrans-53.4-43.7-174.1-71.6-62.3000114.5K46 E365 P367 L445 I446 L447K46-Y443 PolarHBondContact NZ-OH 3.44Å; E365-Y443 WeakPolarHBondContact O-CE1 3.22Å; P367-Y443 HydrophobicContact CG-CD1 4.27Å; P367-Y443 HydrophobicContact CG-CE1 4.09Å; Y443-L445 VanDerWaalsContact C-N 3.32Å; Y443-L445 PolarHBondContact O-N 3.03Å; Y443-I446 PolarHBondContact O-N 3.13Å; Y443-L447 WeakPolarHBondContact O-CB 3.21Å; Y443-L447 PolarHBondContact O-N 3.25Å
444P89.4Confident84.7Confident13 Ų1345.3 Ų45.38%0.08423%0.227CC..Hα-helixtrans-58.7-42.9176.2-25.733.8000112.9C421 N422 V423 I436 C448C421-P444 VanDerWaalsContact O-CD 3.29Å; C421-P444 WeakPolarHBondContact O-CD 3.37Å; C421-P444 WeakPolarHBondContact O-CG 3.31Å; N422-P444 HydrophobicContact CB-CG 4.26Å; V423-P444 HydrophobicContact CG2-CB 3.87Å; V423-P444 HydrophobicContact CG2-CG 4.26Å; I436-P444 HydrophobicContact CD1-CB 4.28Å; I436-P444 HydrophobicContact CG1-CB 4.33Å; I436-P444 HydrophobicContact CG2-CB 3.6Å; I436-P444 HydrophobicContact CG2-CG 3.63Å; P444-C448 PolarHBondContact O-N 2.85Å; P444-C448 PolarHBondContact O-SG 3.37Å
445L89.9Confident85.1Confident13 Ų1344.4 Ų44.47%0.06822%0.222CC..Hα-helixtrans-67.6-44.1177.8171.965.7000111.2F43 T262 E265 L266 N442 Y443 L447 C448 I449F43-L445 HydrophobicContact CE2-CD2 3.57Å; F43-L445 HydrophobicContact CZ-CD2 3.56Å; T262-L445 HydrophobicContact CG2-CB 4.42Å; T262-L445 HydrophobicContact CG2-CD1 3.88Å; E265-L445 HydrophobicContact CB-CD1 3.98Å; E265-L445 HydrophobicContact CB-CD2 4.18Å; E265-L445 HydrophobicContact CG-CD2 4.34Å; L266-L445 HydrophobicContact CD2-CD1 4.4Å; L266-L445 HydrophobicContact CG-CD1 4.25Å; N442-L445 WeakPolarHBondContact O-CB 3.49Å; N442-L445 PolarHBondContact O-N 3.06Å; Y443-L445 VanDerWaalsContact C-N 3.32Å; Y443-L445 PolarHBondContact O-N 3.03Å; L445-L447 VanDerWaalsContact C-N 3.32Å; L445-L447 PolarHBondContact O-N 3.19Å; L445-C448 WeakPolarHBondContact O-CB 3.39Å; L445-C448 PolarHBondContact O-N 2.94Å; L445-C448 VanDerWaalsContact O-N 3.17Å; L445-I449 HydrophobicContact CD1-CD1 3.99Å; L445-I449 HydrophobicContact CD1-CG1 4.2Å; L445-I449 HydrophobicContact CG-CD1 3.88Å; L445-I449 HydrophobicContact CG-CG1 4.49Å; L445-I449 VanDerWaalsContact O-CG1 3.3Å; L445-I449 WeakPolarHBondContact O-CG1 3.44Å; L445-I449 PolarHBondContact O-N 2.82Å
446I92.5Very high85.6Confident5 Ų539.3 Ų39.33%0.02620%0.199CC..Hα-helixtrans-59.6-45.3178.4-66.3161.8000110.2W44 A362 E365 L366 N442 Y443 C448 I449 A450W44-I446 HydrophobicContact CB-CD1 4.41Å; W44-I446 HydrophobicContact CB-CG1 4.07Å; W44-I446 HydrophobicContact CG-CG1 4.01Å; A362-I446 HydrophobicContact CB-CG2 4.47Å; A362-I446 WeakPolarHBondContact O-CG2 3.43Å; E365-I446 HydrophobicContact CB-CD1 4.02Å; E365-I446 HydrophobicContact CB-CG2 3.99Å; L366-I446 HydrophobicContact CD2-CG2 3.84Å; L366-I446 HydrophobicContact CG-CG2 4.14Å; N442-I446 HydrophobicContact CB-CD1 3.88Å; N442-I446 HydrophobicContact CB-CG1 4.24Å; N442-I446 VanDerWaalsContact O-CG1 3.31Å; N442-I446 WeakPolarHBondContact O-CG1 3.46Å; N442-I446 PolarHBondContact O-N 3.29Å; Y443-I446 PolarHBondContact O-N 3.13Å; I446-C448 VanDerWaalsContact C-N 3.35Å; I446-C448 PolarHBondContact O-N 3.26Å; I446-I449 PolarHBondContact O-N 3.46Å; I446-A450 WeakPolarHBondContact O-CB 3.26Å; I446-A450 PolarHBondContact O-N 3.44Å
447L93.4Very high86.1Confident2 Ų237.9 Ų37.91%0.0119%0.192CC..Hα-helixtrans-59.3-44.9174.9179.463.7000111.6L366 V417 F418 C421 V423 Y443 L445 I449 A450 I451L366-L447 HydrophobicContact CD2-CB 4.22Å; L366-L447 HydrophobicContact CD2-CD1 4.31Å; V417-L447 HydrophobicContact CG1-CD1 3.66Å; F418-L447 HydrophobicContact CD1-CD2 3.75Å; F418-L447 HydrophobicContact CE1-CD2 4.05Å; F418-L447 HydrophobicContact CG-CD2 4.2Å; C421-L447 HydrophobicContact CB-CB 3.98Å; C421-L447 HydrophobicContact CB-CD2 3.68Å; C421-L447 HydrophobicContact CB-CG 4.34Å; V423-L447 HydrophobicContact CG2-CD2 4.28Å; Y443-L447 WeakPolarHBondContact O-CB 3.21Å; Y443-L447 PolarHBondContact O-N 3.25Å; L445-L447 VanDerWaalsContact C-N 3.32Å; L445-L447 PolarHBondContact O-N 3.19Å; L447-I449 VanDerWaalsContact C-N 3.34Å; L447-I449 PolarHBondContact O-N 3.05Å; L447-A450 PolarHBondContact O-N 2.81Å; L447-I451 HydrophobicContact CD1-CD1 3.75Å; L447-I451 HydrophobicContact CD1-CG1 4.1Å; L447-I451 HydrophobicContact CD2-CD1 4.45Å; L447-I451 HydrophobicContact CG-CD1 3.82Å; L447-I451 HydrophobicContact CG-CG1 4.49Å; L447-I451 WeakPolarHBondContact O-CB 3.34Å; L447-I451 WeakPolarHBondContact O-CG1 3.4Å; L447-I451 PolarHBondContact O-N 3.17Å
448C92.6Very high86.8Confident4 Ų433.8 Ų33.83%0.02718%0.175CC..Hα-helixtrans-60.4-42.7176.4-66.80000112T262 L266 V390 P444 L445 I446 K452T262-C448 HydrophobicContact CG2-CB 4.47Å; L266-C448 HydrophobicContact CD1-CB 3.93Å; L266-C448 HydrophobicContact CD2-CB 4.1Å; L266-C448 HydrophobicContact CG-CB 4.5Å; V390-C448 HydrophobicContact CG1-CB 3.62Å; V390-C448 HydrophobicContact CG2-CB 4.37Å; P444-C448 PolarHBondContact O-N 2.85Å; P444-C448 PolarHBondContact O-SG 3.37Å; L445-C448 WeakPolarHBondContact O-CB 3.39Å; L445-C448 PolarHBondContact O-N 2.94Å; L445-C448 VanDerWaalsContact O-N 3.17Å; I446-C448 VanDerWaalsContact C-N 3.35Å; I446-C448 PolarHBondContact O-N 3.26Å; C448-K452 WeakPolarHBondContact O-CB 3.39Å; C448-K452 PolarHBondContact O-N 2.93Å
449I94.4Very high87.4Confident0 Ų030.6 Ų30.60%017%0.169CC..Hα-helixtrans-64.6-45177.7-65.4165000110.5W44 L266 L269 F273 L358 A362 L445 I446 L447 S453W44-I449 HydrophobicContact CD2-CD1 3.77Å; W44-I449 HydrophobicContact CE3-CD1 3.86Å; W44-I449 HydrophobicContact CH2-CD1 3.86Å; W44-I449 HydrophobicContact CZ2-CD1 3.73Å; W44-I449 HydrophobicContact CZ2-CG2 4.35Å; W44-I449 HydrophobicContact CZ3-CD1 3.91Å; L266-I449 HydrophobicContact CD2-CG1 3.72Å; L269-I449 HydrophobicContact CD1-CD1 3.64Å; L269-I449 HydrophobicContact CD1-CG1 3.8Å; L269-I449 HydrophobicContact CD1-CG2 4.43Å; F273-I449 HydrophobicContact CE1-CG2 4.32Å; F273-I449 HydrophobicContact CZ-CG2 4.34Å; L358-I449 HydrophobicContact CD1-CG2 4.3Å; L358-I449 HydrophobicContact CD2-CG2 4.44Å; L358-I449 HydrophobicContact CG-CG2 4.16Å; A362-I449 HydrophobicContact CB-CB 4.2Å; A362-I449 HydrophobicContact CB-CG2 3.72Å; L445-I449 HydrophobicContact CD1-CD1 3.99Å; L445-I449 HydrophobicContact CD1-CG1 4.2Å; L445-I449 HydrophobicContact CG-CD1 3.88Å; L445-I449 HydrophobicContact CG-CG1 4.49Å; L445-I449 VanDerWaalsContact O-CG1 3.3Å; L445-I449 WeakPolarHBondContact O-CG1 3.44Å; L445-I449 PolarHBondContact O-N 2.82Å; I446-I449 PolarHBondContact O-N 3.46Å; L447-I449 VanDerWaalsContact C-N 3.34Å; L447-I449 PolarHBondContact O-N 3.05Å; I449-S453 VanDerWaalsContact O-CB 3.26Å; I449-S453 WeakPolarHBondContact O-CB 3.49Å; I449-S453 PolarHBondContact O-N 3.3Å; I449-S453 PolarHBondContact O-OG 2.77Å
450A95.8Very high87.3Confident0 Ų028.3 Ų28.30%018%0.177CC..Hα-helixtrans-61.3-52179.200000111.7A362 L363 L366 I446 L447 K452 S453 L454A362-A450 HydrophobicContact CB-CB 4.19Å; L363-A450 HydrophobicContact CD2-CB 4.08Å; L366-A450 HydrophobicContact CD1-CB 3.95Å; I446-A450 WeakPolarHBondContact O-CB 3.26Å; I446-A450 PolarHBondContact O-N 3.44Å; L447-A450 PolarHBondContact O-N 2.81Å; A450-K452 PolarHBondContact O-N 3.25Å; A450-S453 WeakPolarHBondContact O-CB 3.47Å; A450-S453 PolarHBondContact O-N 3.37Å; A450-L454 WeakPolarHBondContact O-CG 3.48Å; A450-L454 PolarHBondContact O-N 3.39Å
451I95.1Very high87Confident0 Ų024.2 Ų24.20%017%0.166CC..Hα-helixtrans-59.8-48.3178.7-70.7171000110.8L386 V390 F418 L447 S453 L454 A455L386-I451 HydrophobicContact CB-CD1 4.35Å; L386-I451 HydrophobicContact CB-CG2 3.64Å; V390-I451 HydrophobicContact CG2-CB 3.99Å; V390-I451 HydrophobicContact CG2-CD1 3.78Å; V390-I451 HydrophobicContact CG2-CG1 4.49Å; V390-I451 HydrophobicContact CG2-CG2 3.83Å; F418-I451 HydrophobicContact CE1-CD1 3.74Å; F418-I451 HydrophobicContact CZ-CD1 4.14Å; L447-I451 HydrophobicContact CD1-CD1 3.75Å; L447-I451 HydrophobicContact CD1-CG1 4.1Å; L447-I451 HydrophobicContact CD2-CD1 4.45Å; L447-I451 HydrophobicContact CG-CD1 3.82Å; L447-I451 HydrophobicContact CG-CG1 4.49Å; L447-I451 WeakPolarHBondContact O-CB 3.34Å; L447-I451 WeakPolarHBondContact O-CG1 3.4Å; L447-I451 PolarHBondContact O-N 3.17Å; I451-S453 VanDerWaalsContact C-N 3.29Å; I451-S453 PolarHBondContact O-N 3.16Å; I451-L454 PolarHBondContact O-N 2.78Å; I451-A455 VanDerWaalsContact O-CB 3.31Å; I451-A455 WeakPolarHBondContact O-CB 3.3Å; I451-A455 PolarHBondContact O-N 3.13Å
452K93.9Very high87.9Confident35 Ų3523 Ų2315%0.15215%0.149CC..Hα-helixtrans-65.2-34.1-177.9-161.2164-174.5-87.20112.1L266 F273 C448 A450 S456L266-K452 HydrophobicContact CD2-CD 4.34Å; F273-K452 HydrophobicContact CD1-CG 4.39Å; F273-K452 HydrophobicContact CD2-CD 4.08Å; F273-K452 HydrophobicContact CD2-CG 4.17Å; F273-K452 HydrophobicContact CE1-CB 4.21Å; F273-K452 HydrophobicContact CE1-CG 4.42Å; F273-K452 HydrophobicContact CE2-CD 3.85Å; F273-K452 HydrophobicContact CE2-CG 4.2Å; F273-K452 HydrophobicContact CG-CG 4.28Å; F273-K452 HydrophobicContact CZ-CB 4.25Å; F273-K452 HydrophobicContact CZ-CD 4.27Å; F273-K452 HydrophobicContact CZ-CG 4.32Å; C448-K452 WeakPolarHBondContact O-CB 3.39Å; C448-K452 PolarHBondContact O-N 2.93Å; A450-K452 PolarHBondContact O-N 3.25Å; K452-S456 WeakPolarHBondContact O-CB 3.31Å; K452-S456 PolarHBondContact O-N 2.96Å; K452-S456 PolarHBondContact O-OG 3.36Å
453S95.1Very high88.2Confident0 Ų020.5 Ų20.50%014%0.138CC..Hα-helixtrans-65.9-48.3173-61.20000112.5F273 I449 A450 I451 S456 L457F273-S453 WeakPolarHBondContact CE1-OG 3.29Å; I449-S453 VanDerWaalsContact O-CB 3.26Å; I449-S453 WeakPolarHBondContact O-CB 3.49Å; I449-S453 PolarHBondContact O-N 3.3Å; I449-S453 PolarHBondContact O-OG 2.77Å; A450-S453 WeakPolarHBondContact O-CB 3.47Å; A450-S453 PolarHBondContact O-N 3.37Å; I451-S453 VanDerWaalsContact C-N 3.29Å; I451-S453 PolarHBondContact O-N 3.16Å; S453-S456 WeakPolarHBondContact O-CB 3.09Å; S453-S456 PolarHBondContact O-N 2.88Å; S453-L457 PolarHBondContact O-N 3.2Å
454L95.8Very high88.2Confident0 Ų018.3 Ų18.30%013%0.132CC..Hα-helixtrans-65.4-42.2179-67.9168000111.4L288 I291 M295 L363 L374 L383 A450 I451 S456 L457 A458L288-L454 HydrophobicContact CD1-CB 4.47Å; L288-L454 HydrophobicContact CD1-CD2 3.94Å; I291-L454 HydrophobicContact CG2-CD2 4.17Å; M295-L454 HydrophobicContact CE-CD1 4.17Å; M295-L454 HydrophobicContact SD-CD1 4.37Å; M295-L454 HydrophobicContact SD-CD2 4.32Å; L363-L454 HydrophobicContact CD2-CD1 4.29Å; L374-L454 HydrophobicContact CD2-CD1 4.06Å; L374-L454 HydrophobicContact CG-CD1 4.33Å; L383-L454 HydrophobicContact CD1-CB 4.27Å; L383-L454 HydrophobicContact CD2-CB 3.82Å; A450-L454 WeakPolarHBondContact O-CG 3.48Å; A450-L454 PolarHBondContact O-N 3.39Å; I451-L454 PolarHBondContact O-N 2.78Å; L454-S456 VanDerWaalsContact C-N 3.29Å; L454-S456 PolarHBondContact O-N 2.72Å; L454-L457 WeakPolarHBondContact O-CB 3.49Å; L454-L457 PolarHBondContact O-N 3.27Å; L454-L457 VanDerWaalsContact O-N 3.09Å; L454-A458 PolarHBondContact O-N 3.32Å
455A94.3Very high88.1Confident4 Ų418.6 Ų18.63%0.03314%0.135CC..Hα-helixtrans-61-37.1174.100000112.1L383 E387 I451 L457 A458 C459L383-A455 HydrophobicContact CB-CB 4.47Å; E387-A455 HydrophobicContact CB-CB 3.93Å; E387-A455 HydrophobicContact CG-CB 4.27Å; I451-A455 VanDerWaalsContact O-CB 3.31Å; I451-A455 WeakPolarHBondContact O-CB 3.3Å; I451-A455 PolarHBondContact O-N 3.13Å; A455-L457 VanDerWaalsContact C-N 3.26Å; A455-L457 PolarHBondContact O-N 3.27Å; A455-A458 PolarHBondContact O-N 3.23Å; A455-C459 PolarHBondContact O-N 3.42Å
456S94.3Very high88Confident11 Ų1119 Ų198%0.07714%0.139CC..Hα-helixtrans-62.8-32.9174.7-59.30000112.6S277 K452 S453 L454S277-S456 WeakPolarHBondContact CA-O 3.41Å; K452-S456 WeakPolarHBondContact O-CB 3.31Å; K452-S456 PolarHBondContact O-N 2.96Å; K452-S456 PolarHBondContact O-OG 3.36Å; S453-S456 WeakPolarHBondContact O-CB 3.09Å; S453-S456 PolarHBondContact O-N 2.88Å; L454-S456 VanDerWaalsContact C-N 3.29Å; L454-S456 PolarHBondContact O-N 2.72Å
457L93.5Very high87.7Confident0 Ų019.9 Ų19.90%015%0.147CC..Hα-helixtrans-79.3-18.5173.3-67.6171.8000113.2L276 R284 L287 L288 I291 S453 L454 A455 C461L276-L457 HydrophobicContact CB-CD2 4.09Å; L276-L457 HydrophobicContact CB-CG 4.42Å; L276-L457 HydrophobicContact CD2-CD2 4.12Å; R284-L457 HydrophobicContact CB-CD2 4.49Å; R284-L457 WeakPolarHBondContact CB-O 3.47Å; R284-L457 HydrophobicContact CG-CD2 4.43Å; L287-L457 HydrophobicContact CB-CD1 4.45Å; L287-L457 HydrophobicContact CB-CD2 4.17Å; L287-L457 HydrophobicContact CD1-CD2 4.05Å; L288-L457 HydrophobicContact CB-CB 4.12Å; L288-L457 HydrophobicContact CD1-CB 4.37Å; I291-L457 HydrophobicContact CD1-CD1 3.92Å; S453-L457 PolarHBondContact O-N 3.2Å; L454-L457 WeakPolarHBondContact O-CB 3.49Å; L454-L457 PolarHBondContact O-N 3.27Å; L454-L457 VanDerWaalsContact O-N 3.09Å; A455-L457 VanDerWaalsContact C-N 3.26Å; A455-L457 PolarHBondContact O-N 3.27Å; L457-C461 PolarHBondContact O-SG 2.8Å
458A89.3Confident87.3Confident7 Ų721.2 Ų21.26%0.05816%0.156CC..Hα-helixtrans-92.8-14177.800000113.8L288 P380 L383 L454 A455 G460 C461L288-A458 HydrophobicContact CD2-CB 3.84Å; P380-A458 HydrophobicContact CB-CB 4.45Å; L383-A458 HydrophobicContact CB-CB 4.41Å; L383-A458 HydrophobicContact CD1-CB 3.67Å; L454-A458 PolarHBondContact O-N 3.32Å; A455-A458 PolarHBondContact O-N 3.23Å; A458-G460 PolarHBondContact O-N 3.39Å; A458-C461 WeakPolarHBondContact O-CB 3.2Å; A458-C461 PolarHBondContact O-N 2.95Å
459C76.4Confident86.9Confident78 Ų7822.5 Ų22.553%0.52717%0.166SC..THydrogen-bonded Turntrans-63.4104.6-171-175.40000112.8R284 A455R284-C459 PolarHBondContact NH1-O 3.38Å; R284-C459 PolarHBondContact NH2-O 3.42Å; A455-C459 PolarHBondContact O-N 3.42Å
460G59.5Low86.3Confident70 Ų7024.4 Ų24.472%0.72218%0.18SC*.THydrogen-bonded Turntrans80.126.9179.900000114.2R284 A458R284-G460 PolarHBondContact NH2-O 3.3Å; A458-G460 PolarHBondContact O-N 3.39Å
461C52.2Low85.4Confident88 Ų8826.6 Ų26.660%0.59520%0.197SC*.  trans-92.40168.1-64.60000111.7S285 L457 A458S285-C461 WeakPolarHBondContact OG-CB 3.04Å; S285-C461 PolarHBondContact OG-SG 3.14Å; L457-C461 PolarHBondContact O-SG 2.8Å; A458-C461 WeakPolarHBondContact O-CB 3.2Å; A458-C461 PolarHBondContact O-N 2.95Å

Retrieved 461 of 461 residues in 434.7 ms (Link to these results)