A0A087XA41_POEFO Loading...

Glutamine-dependent NAD(+) synthetase

AlphaFold DB , UniProt , Accession A0A087XA41, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 620 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M97.1Very high98.1Very high136 Ų13674.4 Ų74.467%0.6737%0.373SS*.  0152.2066.3-178.6-71.700110I3 C12 V14M1-I3 HydrophobicContact CG-CD1 4.12Å; M1-I3 HydrophobicContact CG-CG1 4.09Å; M1-C12 PolarHBondContact N-O 2.81Å; M1-C12 WeakPolarHBondContact O-CB 3.11Å; M1-C12 PolarHBondContact O-N 2.68Å; M1-C12 VanDerWaalsContact O-O 3.14Å; M1-V14 HydrophobicContact CG-CG2 3.81Å; M1-V14 HydrophobicContact SD-CG2 3.85Å
2P98.4Very high98.1Very high81 Ų8168.2 Ų68.253%0.52634%0.342SS..EExtended strand (participates in β ladder)trans-71.1136.4174.230.8-36.1000111.2Y10 F42P2-Y10 WeakPolarHBondContact CA-O 3.29Å; P2-F42 HydrophobicContact CB-CE1 3.64Å; P2-F42 HydrophobicContact CB-CZ 4.02Å
3I98.6Very high98.1Very high12 Ų1270.8 Ų70.86%0.06235%0.345CS..EExtended strand (participates in β ladder)trans-135.2137.2178.5-66.4178.1000110M1 Y10 C12 V14 I24 Y54 F71M1-I3 HydrophobicContact CG-CD1 4.12Å; M1-I3 HydrophobicContact CG-CG1 4.09Å; I3-Y10 PolarHBondContact N-O 3.2Å; I3-Y10 PolarHBondContact O-N 3.11Å; I3-C12 HydrophobicContact CB-CB 4.36Å; I3-C12 HydrophobicContact CD1-CB 3.92Å; I3-C12 HydrophobicContact CG1-CB 4.23Å; I3-V14 HydrophobicContact CD1-CG2 3.64Å; I3-I24 HydrophobicContact CD1-CD1 4.06Å; I3-I24 HydrophobicContact CD1-CG1 4.37Å; I3-I24 HydrophobicContact CD1-CG2 3.52Å; I3-Y54 HydrophobicContact CG2-CD2 4.27Å; I3-Y54 HydrophobicContact CG2-CE2 3.5Å; I3-F71 HydrophobicContact CG2-CE2 3.95Å
4M98.4Very high98.1Very high87 Ų8768.6 Ų68.643%0.42934%0.338SS..EExtended strand (participates in β ladder)trans-96.3113.4174.1-67.7-69-61.800109.2N7 V8 R9 Y54M4-N7 VanDerWaalsContact CE-C 3.5Å; M4-N7 WeakPolarHBondContact CE-O 3.41Å; M4-V8 CarbonylContact C-O 3.51Å; M4-V8 VanDerWaalsContact CA-O 3.31Å; M4-V8 WeakPolarHBondContact CA-O 3.4Å; M4-R9 VanDerWaalsContact SD-CA 3.53Å; M4-R9 HydrophobicContact SD-CB 3.37Å; M4-R9 WeakPolarHBondContact SD-CB 3.44Å; M4-R9 HydrophobicContact SD-CG 3.61Å; M4-Y54 WeakPolarHBondContact O-CE2 3.44Å
5H98.2Very high98.2Very high7 Ų766 Ų663%0.03233%0.326CS..EExtended strand (participates in β ladder)trans-120.5127.9175.2-179.950.2000109.6N7 V8 Y10 E52 E53 Y54 F71H5-N7 PolarHBondContact O-N 2.79Å; H5-V8 PolarHBondContact N-O 3.35Å; H5-V8 WeakPolarHBondContact O-CB 3.35Å; H5-V8 PolarHBondContact O-N 3Å; H5-Y10 HydrophobicContact CB-CD2 4.11Å; H5-Y10 HydrophobicContact CB-CE2 3.96Å; H5-E52 IonicContact CD2-OE2 3.96Å; H5-E52 PolarHBondContact CD2-OE2 3.17Å; H5-E52 IonicContact CE1-OE2 3.89Å; H5-E52 IonicContact NE2-OE2 2.71Å; H5-E52 PolarHBondContact NE2-OE2 2.9Å; H5-E53 PolarHBondContact CE1-O 2.9Å; H5-Y54 HydrophobicContact CB-CD2 4.05Å; H5-Y54 HydrophobicContact CB-CE2 4.31Å; H5-Y54 AromaticContact ND1-CD2 3.55Å; H5-F71 HydrophobicContact CB-CD1 4.39Å; H5-F71 HydrophobicContact CB-CD2 4.36Å; H5-F71 HydrophobicContact CB-CE1 3.96Å; H5-F71 HydrophobicContact CB-CE2 3.93Å; H5-F71 HydrophobicContact CB-CZ 3.72Å; H5-F71 AromaticContact CD2-CD1 3.55Å; H5-F71 AromaticContact CD2-CE1 3.66Å
6H96.6Very high98.1Very high122 Ų12271.3 Ų71.357%0.56535%0.347SS*.THydrogen-bonded Turntrans46.745.1-172.7-62157000113.6V8 E52H6-V8 PolarHBondContact O-N 3.08Å; H6-E52 IonicContact CE1-OE1 3.73Å; H6-E52 IonicContact CE1-OE2 3.73Å; H6-E52 IonicContact ND1-OE1 3.87Å; H6-E52 IonicContact ND1-OE2 3.57Å
7N97.3Very high98.1Very high154 Ų15469.6 Ų69.682%0.82434%0.339SS*.THydrogen-bonded Turntrans62.315.2-175.6-67.1-40.5000116M4 H5M4-N7 VanDerWaalsContact CE-C 3.5Å; M4-N7 WeakPolarHBondContact CE-O 3.41Å; H5-N7 PolarHBondContact O-N 2.79Å
8V98.3Very high98.1Very high47 Ų4773.1 Ų73.129%0.28536%0.36SS..EExtended strand (participates in β ladder)trans-110.5132.4174.8-1780000109.9M4 H5 H6 Y10 S43M4-V8 CarbonylContact C-O 3.51Å; M4-V8 VanDerWaalsContact CA-O 3.31Å; M4-V8 WeakPolarHBondContact CA-O 3.4Å; H5-V8 PolarHBondContact N-O 3.35Å; H5-V8 WeakPolarHBondContact O-CB 3.35Å; H5-V8 PolarHBondContact O-N 3Å; H6-V8 PolarHBondContact O-N 3.08Å; V8-Y10 HydrophobicContact CB-CD2 4.43Å; V8-Y10 HydrophobicContact CB-CE2 3.59Å; V8-Y10 HydrophobicContact CG1-CD2 4.3Å; V8-Y10 HydrophobicContact CG1-CE1 4.02Å; V8-Y10 HydrophobicContact CG1-CE2 3.62Å; V8-Y10 VanDerWaalsContact CG1-CZ 3.45Å; V8-Y10 WeakPolarHBondContact CG1-OH 3.21Å; V8-Y10 WeakPolarHBondContact O-CD2 3.22Å; V8-Y10 WeakPolarHBondContact O-CE2 3.33Å; V8-S43 VanDerWaalsContact CG1-CB 3.44Å; V8-S43 WeakPolarHBondContact CG1-OG 3.38Å
9R98.7Very high98.1Very high111 Ų11179.8 Ų79.842%0.41938%0.381SS..EExtended strand (participates in β ladder)trans-86127.3179.1-158.6-177.7-67.2113.4-1.7110.7M4 W41 F42 S43M4-R9 VanDerWaalsContact SD-CA 3.53Å; M4-R9 HydrophobicContact SD-CB 3.37Å; M4-R9 WeakPolarHBondContact SD-CB 3.44Å; M4-R9 HydrophobicContact SD-CG 3.61Å; R9-W41 WeakPolarHBondContact CD-O 3.36Å; R9-W41 PolarHBondContact NH1-O 3.46Å; R9-F42 HydrophobicContact CB-CD1 4.25Å; R9-F42 HydrophobicContact CG-CD1 3.67Å; R9-F42 HydrophobicContact CG-CE1 3.73Å; R9-F42 CarbonylContact O-C 3.51Å; R9-F42 WeakPolarHBondContact O-CA 3.41Å; R9-S43 PolarHBondContact O-N 2.75Å
10Y98.8Very high98.1Very high25 Ų2580.4 Ų80.410%0.09838%0.381CS..EExtended strand (participates in β ladder)trans-120.5146.6176.9-61.4-85.1000111.1P2 I3 H5 V8 C12 P26 S43 W45 F71P2-Y10 WeakPolarHBondContact CA-O 3.29Å; I3-Y10 PolarHBondContact N-O 3.2Å; I3-Y10 PolarHBondContact O-N 3.11Å; H5-Y10 HydrophobicContact CB-CD2 4.11Å; H5-Y10 HydrophobicContact CB-CE2 3.96Å; V8-Y10 HydrophobicContact CB-CD2 4.43Å; V8-Y10 HydrophobicContact CB-CE2 3.59Å; V8-Y10 HydrophobicContact CG1-CD2 4.3Å; V8-Y10 HydrophobicContact CG1-CE1 4.02Å; V8-Y10 HydrophobicContact CG1-CE2 3.62Å; V8-Y10 VanDerWaalsContact CG1-CZ 3.45Å; V8-Y10 WeakPolarHBondContact CG1-OH 3.21Å; V8-Y10 WeakPolarHBondContact O-CD2 3.22Å; V8-Y10 WeakPolarHBondContact O-CE2 3.33Å; Y10-C12 WeakPolarHBondContact CB-SG 3.29Å; Y10-P26 HydrophobicContact CD1-CB 3.87Å; Y10-P26 HydrophobicContact CG-CB 3.96Å; Y10-S43 WeakPolarHBondContact CD1-O 3.48Å; Y10-W45 HydrophobicContact CE1-CB 4.41Å; Y10-W45 AromaticContact CE1-CE3 3.95Å; Y10-W45 HydrophobicContact CE1-CE3 3.95Å; Y10-F71 HydrophobicContact CD2-CE1 4.07Å; Y10-F71 AromaticContact CD2-CZ 3.55Å; Y10-F71 HydrophobicContact CD2-CZ 3.55Å; Y10-F71 HydrophobicContact CE2-CE1 4.17Å; Y10-F71 HydrophobicContact CE2-CZ 4.09Å; Y10-F71 HydrophobicContact CG-CE1 4.41Å; Y10-F71 AromaticContact CG-CZ 3.86Å; Y10-F71 HydrophobicContact CG-CZ 3.86Å
11N98.6Very high98.1Very high36 Ų3677.5 Ų77.519%0.19337%0.368CS..EExtended strand (participates in β ladder)trans-83.5110.8165.5179.3-3.8000107.5P26 K27 M30 F42N11-P26 CarbonylContact O-C 3.42Å; N11-K27 HydrophobicContact CB-CB 4.12Å; N11-K27 HydrophobicContact CB-CD 4.45Å; N11-K27 VanDerWaalsContact O-CB 3.28Å; N11-K27 WeakPolarHBondContact O-CB 3.38Å; N11-K27 PolarHBondContact O-N 3.16Å; N11-M30 HydrophobicContact CB-CE 4.44Å; N11-F42 HydrophobicContact CB-CD1 4.2Å; N11-F42 HydrophobicContact CB-CD2 4.24Å; N11-F42 HydrophobicContact CB-CE1 4.43Å; N11-F42 HydrophobicContact CB-CE2 4.47Å; N11-F42 HydrophobicContact CB-CG 4.1Å
12C98.5Very high98.1Very high0 Ų072.6 Ų72.60%035%0.345CS..EExtended strand (participates in β ladder)trans-120.1153.2-168.9-61.10000114M1 I3 Y10 I24 R25M1-C12 PolarHBondContact N-O 2.81Å; M1-C12 WeakPolarHBondContact O-CB 3.11Å; M1-C12 PolarHBondContact O-N 2.68Å; M1-C12 VanDerWaalsContact O-O 3.14Å; I3-C12 HydrophobicContact CB-CB 4.36Å; I3-C12 HydrophobicContact CD1-CB 3.92Å; I3-C12 HydrophobicContact CG1-CB 4.23Å; Y10-C12 WeakPolarHBondContact CB-SG 3.29Å; C12-I24 HydrophobicContact CB-CG2 3.8Å; C12-R25 CarbonylContact C-O 3.6Å; C12-R25 WeakPolarHBondContact CA-O 3.27Å
13R98.3Very high98.1Very high103 Ų10368.8 Ų68.839%0.38932%0.32SS..EExtended strand (participates in β ladder)trans-97.3137.1159-63.1-67.6-72.7176.26109L15 I24 R25 T85 I87 S112R13-L15 HydrophobicContact CB-CD1 4.05Å; R13-I24 CarbonylContact O-C 3.56Å; R13-I24 VanDerWaalsContact O-CA 3.31Å; R13-I24 WeakPolarHBondContact O-CA 3.29Å; R13-R25 HydrophobicContact CB-CB 4.41Å; R13-R25 PolarHBondContact N-O 3.37Å; R13-R25 PolarHBondContact O-N 2.92Å; R13-T85 HydrophobicContact CB-CG2 4.19Å; R13-T85 HydrophobicContact CG-CG2 3.82Å; R13-I87 HydrophobicContact CG-CD1 3.58Å; R13-I87 HydrophobicContact CG-CG1 3.81Å; R13-S112 WeakPolarHBondContact CD-OG 3.34Å; R13-S112 PolarHBondContact NE-OG 3.16Å; R13-S112 PolarHBondContact NH1-OG 3.15Å; R13-S112 VanDerWaalsContact NH1-OG 3.14Å
14V98.4Very high98.1Very high39 Ų3968.4 Ų68.424%0.23632%0.318CS..EExtended strand (participates in β ladder)trans-116112.8174.2-1770000106.5M1 I3 I21 I24M1-V14 HydrophobicContact CG-CG2 3.81Å; M1-V14 HydrophobicContact SD-CG2 3.85Å; I3-V14 HydrophobicContact CD1-CG2 3.64Å; V14-I21 HydrophobicContact CG1-CD1 4.32Å; V14-I21 HydrophobicContact CG1-CG1 4.16Å; V14-I21 HydrophobicContact CG1-CG2 4.01Å; V14-I24 HydrophobicContact CG1-CG1 4.46Å; V14-I24 HydrophobicContact CG2-CG1 4.33Å
15L98.3Very high98.1Very high30 Ų3064.3 Ų64.316%0.15730%0.297CS..EExtended strand (participates in β ladder)trans-99.7126.1178.6-63.584.2000107.4R13 L22 L23 L76R13-L15 HydrophobicContact CB-CD1 4.05Å; L15-L22 PolarHBondContact O-N 2.85Å; L15-L23 HydrophobicContact CB-CB 4.43Å; L15-L23 HydrophobicContact CD1-CB 4.31Å; L15-L23 HydrophobicContact CD1-CD2 4.32Å; L15-L23 HydrophobicContact CD1-CG 4.25Å; L15-L23 PolarHBondContact N-O 2.81Å; L15-L23 PolarHBondContact O-N 2.98Å; L15-L76 HydrophobicContact CB-CD1 4.29Å; L15-L76 HydrophobicContact CD2-CD1 3.56Å; L15-L76 HydrophobicContact CD2-CG 4.15Å
16F98Very high98.1Very high151 Ų15164 Ų6466%0.66230%0.296SS*.EExtended strand (participates in β ladder)trans-141.8152.4-177.665.5-88.9000110.8K20 I21F16-K20 CarbonylContact C-O 3.52Å; F16-K20 WeakPolarHBondContact CA-O 3.44Å; F16-K20 VanDerWaalsContact CB-O 3.24Å; F16-K20 WeakPolarHBondContact CB-O 3.37Å; F16-I21 HydrophobicContact CB-CG1 4.23Å
17L98.1Very high98.2Very high42 Ų4258.2 Ų58.222%0.2227%0.269CS..EExtended strand (participates in β ladder)trans-144.7133.4178.4177.165.5000108.2R19 K20 L22 V215 F217L17-R19 PolarHBondContact O-N 3.33Å; L17-K20 PolarHBondContact N-O 3.46Å; L17-K20 PolarHBondContact O-N 3.2Å; L17-L22 HydrophobicContact CB-CD1 3.85Å; L17-L22 HydrophobicContact CB-CD2 4.47Å; L17-L22 HydrophobicContact CB-CG 4.3Å; L17-V215 HydrophobicContact CD2-CG1 3.94Å; L17-F217 HydrophobicContact CD1-CD2 4.43Å; L17-F217 HydrophobicContact CD1-CE2 4.34Å; L17-F217 HydrophobicContact CD2-CB 3.69Å; L17-F217 HydrophobicContact CD2-CD1 4.2Å; L17-F217 HydrophobicContact CD2-CD2 3.78Å; L17-F217 HydrophobicContact CD2-CE2 4.49Å; L17-F217 HydrophobicContact CD2-CG 3.62Å
18N97.3Very high98.2Very high132 Ų13252 Ų5271%0.70624%0.236SC*.THydrogen-bonded Turntrans47.453173.2-62.6-26.3000114.1K20N18-K20 PolarHBondContact O-N 3.23Å
19R97.5Very high98Very high202 Ų20252.3 Ų52.376%0.76224%0.235SC*.THydrogen-bonded Turntrans63.113.4-177.8-55-177.9176.5-179.3-1.1115.6L17 T64L17-R19 PolarHBondContact O-N 3.33Å; R19-T64 VanDerWaalsContact O-CA 3.29Å; R19-T64 WeakPolarHBondContact O-CA 3.5Å; R19-T64 VanDerWaalsContact O-CB 3.27Å; R19-T64 WeakPolarHBondContact O-CB 3.24Å; R19-T64 VanDerWaalsContact O-CG2 3.29Å; R19-T64 WeakPolarHBondContact O-CG2 3.46Å
20K98.3Very high97.9Very high90 Ų9048.1 Ų48.139%0.39122%0.221SC..EExtended strand (participates in β ladder)trans-115.3132.3172.8-65.7-71.9-173.4176.10110.3F16 L17 N18 T64 G65 Q66F16-K20 CarbonylContact C-O 3.52Å; F16-K20 WeakPolarHBondContact CA-O 3.44Å; F16-K20 VanDerWaalsContact CB-O 3.24Å; F16-K20 WeakPolarHBondContact CB-O 3.37Å; L17-K20 PolarHBondContact N-O 3.46Å; L17-K20 PolarHBondContact O-N 3.2Å; N18-K20 PolarHBondContact O-N 3.23Å; K20-T64 VanDerWaalsContact CD-O 3.29Å; K20-T64 WeakPolarHBondContact CD-O 3.35Å; K20-T64 WeakPolarHBondContact CE-O 3.34Å; K20-T64 PolarHBondContact NZ-O 2.71Å; K20-G65 PolarHBondContact NZ-O 2.85Å; K20-G65 VanDerWaalsContact NZ-O 3.16Å; K20-Q66 VanDerWaalsContact CA-OE1 3.26Å; K20-Q66 HydrophobicContact CD-CG 3.59Å
21I98.5Very high97.7Very high21 Ų2147.3 Ų47.311%0.10822%0.219CC..EExtended strand (participates in β ladder)trans-79.7124.5169.8-66.3166.6000107.4V14 F16 I24 L56 I60 Q66 V69V14-I21 HydrophobicContact CG1-CD1 4.32Å; V14-I21 HydrophobicContact CG1-CG1 4.16Å; V14-I21 HydrophobicContact CG1-CG2 4.01Å; F16-I21 HydrophobicContact CB-CG1 4.23Å; I21-I24 HydrophobicContact CG2-CG1 4.16Å; I21-L56 HydrophobicContact CD1-CD1 4.3Å; I21-L56 HydrophobicContact CD1-CD2 3.65Å; I21-I60 HydrophobicContact CD1-CG2 3.68Å; I21-Q66 PolarHBondContact O-NE2 2.66Å; I21-V69 HydrophobicContact CB-CG1 3.83Å; I21-V69 HydrophobicContact CG2-CB 4.06Å; I21-V69 HydrophobicContact CG2-CG1 3.82Å; I21-V69 HydrophobicContact CG2-CG2 4.06Å
22L98.3Very high97.6Very high33 Ų3349.4 Ų49.417%0.17323%0.231CC..EExtended strand (participates in β ladder)trans-89.8-43.1-178.8-56.7178.3000111.1L15 L17 L76 V215L15-L22 PolarHBondContact O-N 2.85Å; L17-L22 HydrophobicContact CB-CD1 3.85Å; L17-L22 HydrophobicContact CB-CD2 4.47Å; L17-L22 HydrophobicContact CB-CG 4.3Å; L22-L76 HydrophobicContact CB-CD2 4.15Å; L22-L76 HydrophobicContact CD1-CD1 4.02Å; L22-V215 HydrophobicContact CD1-CG1 3.92Å; L22-V215 HydrophobicContact CD1-CG2 3.99Å; L22-V215 HydrophobicContact CD2-CG1 4.29Å; L22-V215 HydrophobicContact CD2-CG2 4.45Å
23L98.3Very high97.3Very high1 Ų153.6 Ų53.61%0.00526%0.259CS..EExtended strand (participates in β ladder)trans-157.6138.5-173.9171.158000111.3L15 R25 P70 C74 L76L15-L23 HydrophobicContact CB-CB 4.43Å; L15-L23 HydrophobicContact CD1-CB 4.31Å; L15-L23 HydrophobicContact CD1-CD2 4.32Å; L15-L23 HydrophobicContact CD1-CG 4.25Å; L15-L23 PolarHBondContact N-O 2.81Å; L15-L23 PolarHBondContact O-N 2.98Å; L23-R25 HydrophobicContact CD2-CB 4.24Å; L23-R25 HydrophobicContact CG-CB 4.26Å; L23-P70 HydrophobicContact CD1-CB 4.25Å; L23-C74 WeakPolarHBondContact CD1-SG 3.31Å; L23-C74 WeakPolarHBondContact CD2-SG 3.36Å; L23-L76 HydrophobicContact CB-CD2 4.09Å; L23-L76 HydrophobicContact CD2-CD2 4.32Å
24I98.6Very high97.1Very high3 Ų350.2 Ų50.22%0.01526%0.257CS..EExtended strand (participates in β ladder)trans-105.5108.4160.1-57.3172.3000109.1I3 C12 R13 V14 I21 P26 Y54 V69 P70 F71 G72I3-I24 HydrophobicContact CD1-CD1 4.06Å; I3-I24 HydrophobicContact CD1-CG1 4.37Å; I3-I24 HydrophobicContact CD1-CG2 3.52Å; C12-I24 HydrophobicContact CB-CG2 3.8Å; R13-I24 CarbonylContact O-C 3.56Å; R13-I24 VanDerWaalsContact O-CA 3.31Å; R13-I24 WeakPolarHBondContact O-CA 3.29Å; V14-I24 HydrophobicContact CG1-CG1 4.46Å; V14-I24 HydrophobicContact CG2-CG1 4.33Å; I21-I24 HydrophobicContact CG2-CG1 4.16Å; I24-P26 VanDerWaalsContact O-CD 3.29Å; I24-P26 WeakPolarHBondContact O-CD 3.21Å; I24-Y54 HydrophobicContact CD1-CD1 3.44Å; I24-Y54 VanDerWaalsContact CD1-CD1 3.44Å; I24-Y54 HydrophobicContact CD1-CE1 3.83Å; I24-Y54 HydrophobicContact CD1-CG 3.98Å; I24-V69 HydrophobicContact CD1-CG2 3.5Å; I24-V69 HydrophobicContact CG1-CG2 3.98Å; I24-P70 PolarHBondContact N-O 2.57Å; I24-F71 HydrophobicContact CB-CD2 3.69Å; I24-F71 HydrophobicContact CB-CE2 4.34Å; I24-F71 HydrophobicContact CB-CG 4.45Å; I24-F71 HydrophobicContact CD1-CD2 4.4Å; I24-F71 HydrophobicContact CG2-CD2 3.35Å; I24-F71 HydrophobicContact CG2-CE2 3.49Å; I24-F71 VanDerWaalsContact CG2-CE2 3.49Å; I24-F71 HydrophobicContact CG2-CG 4.41Å; I24-F71 VanDerWaalsContact O-CA 3.29Å; I24-F71 WeakPolarHBondContact O-CA 3.28Å; I24-G72 PolarHBondContact O-N 2.96Å
25R98.3Very high96.9Very high1 Ų149.2 Ų49.20%0.00425%0.251CS..EExtended strand (participates in β ladder)trans-99106.8178.4171.756.2169.55416.6110.4C12 R13 L23 M28 G72 D73 T85 E90C12-R25 CarbonylContact C-O 3.6Å; C12-R25 WeakPolarHBondContact CA-O 3.27Å; R13-R25 HydrophobicContact CB-CB 4.41Å; R13-R25 PolarHBondContact N-O 3.37Å; R13-R25 PolarHBondContact O-N 2.92Å; L23-R25 HydrophobicContact CD2-CB 4.24Å; L23-R25 HydrophobicContact CG-CB 4.26Å; R25-M28 PolarHBondContact NH2-SD 2.94Å; R25-G72 WeakPolarHBondContact CD-O 3.34Å; R25-D73 IonicContact NE-OD1 3.57Å; R25-D73 PolarHBondContact NE-OD1 3.15Å; R25-D73 IonicContact NH2-OD1 3.12Å; R25-T85 HydrophobicContact CG-CG2 4.42Å; R25-T85 PolarHBondContact NH2-O 3.09Å; R25-E90 IonicContact CZ-OE1 3.97Å; R25-E90 IonicContact CZ-OE2 3.35Å; R25-E90 IonicContact NH1-OE1 2.77Å; R25-E90 PolarHBondContact NH1-OE1 3.19Å; R25-E90 IonicContact NH1-OE2 3.33Å; R25-E90 IonicContact NH2-OE1 3.17Å; R25-E90 IonicContact NH2-OE2 2.57Å; R25-E90 PolarHBondContact NH2-OE2 3.34Å
26P98.3Very high96.8Very high0 Ų049.7 Ų49.70%025%0.251CS..EExtended strand (participates in β ladder)trans-75.4143.5173.432.3-37.4000111.7Y10 N11 I24 W45 F71Y10-P26 HydrophobicContact CD1-CB 3.87Å; Y10-P26 HydrophobicContact CG-CB 3.96Å; N11-P26 CarbonylContact O-C 3.42Å; I24-P26 VanDerWaalsContact O-CD 3.29Å; I24-P26 WeakPolarHBondContact O-CD 3.21Å; P26-W45 HydrophobicContact CB-CB 3.9Å; P26-W45 HydrophobicContact CB-CG 4.42Å; P26-W45 HydrophobicContact CG-CB 3.53Å; P26-W45 HydrophobicContact CG-CD2 3.67Å; P26-W45 HydrophobicContact CG-CE3 3.89Å; P26-W45 HydrophobicContact CG-CG 3.54Å; P26-F71 HydrophobicContact CB-CE1 3.93Å; P26-F71 HydrophobicContact CB-CZ 3.75Å; P26-F71 HydrophobicContact CG-CD1 4.19Å; P26-F71 HydrophobicContact CG-CE1 3.59Å; P26-F71 HydrophobicContact CG-CZ 3.91Å
27K98.1Very high96.8Very high1 Ų146 Ų460%0.00423%0.233CC..  trans-62.6135174.4-167173.7-162.3-163.30111N11 L29 M30 E38 W45 I87 E90N11-K27 HydrophobicContact CB-CB 4.12Å; N11-K27 HydrophobicContact CB-CD 4.45Å; N11-K27 VanDerWaalsContact O-CB 3.28Å; N11-K27 WeakPolarHBondContact O-CB 3.38Å; N11-K27 PolarHBondContact O-N 3.16Å; K27-L29 WeakPolarHBondContact CE-O 3.39Å; K27-L29 WeakPolarHBondContact CG-O 3.29Å; K27-M30 HydrophobicContact CB-CE 4.4Å; K27-M30 HydrophobicContact CB-SD 4.42Å; K27-M30 HydrophobicContact CD-SD 3.9Å; K27-M30 HydrophobicContact CG-SD 4.23Å; K27-E38 IonicContact NZ-OE1 2.65Å; K27-E38 PolarHBondContact NZ-OE1 3.24Å; K27-E38 IonicContact NZ-OE2 2.66Å; K27-E38 PolarHBondContact NZ-OE2 2.99Å; K27-W45 PolarHBondContact O-N 2.85Å; K27-I87 HydrophobicContact CB-CB 4.44Å; K27-I87 HydrophobicContact CB-CD1 3.9Å; K27-I87 HydrophobicContact CB-CG2 4.44Å; K27-I87 HydrophobicContact CD-CB 4.2Å; K27-I87 HydrophobicContact CD-CG2 3.76Å; K27-I87 WeakPolarHBondContact CE-O 3.44Å; K27-I87 HydrophobicContact CG-CB 3.99Å; K27-I87 HydrophobicContact CG-CD1 4.38Å; K27-I87 HydrophobicContact CG-CG2 4.07Å; K27-E90 WeakPolarHBondContact CA-OE1 3.48Å
28M96.6Very high96.8Very high25 Ų2545.4 Ų45.412%0.12323%0.229CC..SBendtrans-102.5-30-174.6-69.716740.900112R25 P44 W45 L48 D73 E90R25-M28 PolarHBondContact NH2-SD 2.94Å; M28-P44 WeakPolarHBondContact O-CB 3.47Å; M28-W45 HydrophobicContact CG-CB 3.89Å; M28-W45 HydrophobicContact CG-CG 4.36Å; M28-L48 HydrophobicContact CE-CD2 3.22Å; M28-L48 HydrophobicContact SD-CD2 4.44Å; M28-D73 HydrophobicContact SD-CB 3.74Å; M28-D73 VanDerWaalsContact SD-CG 3.51Å; M28-E90 PolarHBondContact N-OE1 2.81Å
29L95.5Very high96.8Very high52 Ų5244.3 Ų44.327%0.27222%0.221SC..SBendtrans-121.7119.6179.4-60.6169.1000110.1K27 E90 N93K27-L29 WeakPolarHBondContact CE-O 3.39Å; K27-L29 WeakPolarHBondContact CG-O 3.29Å; L29-E90 HydrophobicContact CB-CG 3.81Å; L29-E90 HydrophobicContact CD1-CB 4.48Å; L29-E90 HydrophobicContact CD1-CG 4.18Å; L29-E90 HydrophobicContact CG-CG 4.23Å; L29-N93 HydrophobicContact CD1-CB 3.59Å
30M95.7Very high96.8Very high23 Ų2343.8 Ų43.811%0.11322%0.219CC..  trans-95.7139.6-174.3-66.7-61.4-16800112N11 K27 N32 E38 M39 F42 S43 P44N11-M30 HydrophobicContact CB-CE 4.44Å; K27-M30 HydrophobicContact CB-CE 4.4Å; K27-M30 HydrophobicContact CB-SD 4.42Å; K27-M30 HydrophobicContact CD-SD 3.9Å; K27-M30 HydrophobicContact CG-SD 4.23Å; M30-N32 PolarHBondContact O-N 3.47Å; M30-E38 VanDerWaalsContact CA-OE2 3.3Å; M30-E38 WeakPolarHBondContact CA-OE2 3.48Å; M30-E38 HydrophobicContact CB-CB 4.13Å; M30-E38 HydrophobicContact CG-CB 4.42Å; M30-E38 HydrophobicContact SD-CB 3.85Å; M30-E38 VanDerWaalsContact SD-OE2 3.34Å; M30-M39 HydrophobicContact CB-CE 3.94Å; M30-M39 HydrophobicContact CB-CG 3.84Å; M30-M39 HydrophobicContact CG-CG 4.25Å; M30-F42 HydrophobicContact CE-CB 3.32Å; M30-F42 HydrophobicContact CE-CG 4.38Å; M30-F42 HydrophobicContact SD-CB 4.35Å; M30-S43 VanDerWaalsContact CE-C 3.42Å; M30-S43 WeakPolarHBondContact CE-O 3.29Å; M30-P44 HydrophobicContact CG-CB 4.16Å
31A95.1Very high96.8Very high8 Ų846.1 Ų46.17%0.06623%0.225CC..  trans-80.4115.6169.900000109.5Y36 E38 A89A31-Y36 HydrophobicContact CB-CD1 4.39Å; A31-Y36 HydrophobicContact CB-CD2 4.14Å; A31-Y36 HydrophobicContact CB-CG 3.82Å; A31-Y36 CarbonylContact O-C 3.41Å; A31-Y36 WeakPolarHBondContact O-CB 3.5Å; A31-E38 HydrophobicContact CB-CG 4.41Å; A31-E38 PolarHBondContact N-OE2 2.86Å; A31-E38 WeakPolarHBondContact O-CB 3.31Å; A31-E38 PolarHBondContact O-N 2.91Å; A31-A89 HydrophobicContact CB-CB 4.05Å
32N95.2Very high96.8Very high81 Ų8147.1 Ų47.143%0.43323%0.229SC..  trans-137.132.4-176.7-152.376.1000112.8M30 Y36 R37 M39M30-N32 PolarHBondContact O-N 3.47Å; N32-Y36 CarbonylContact C-O 3.48Å; N32-Y36 VanDerWaalsContact CA-O 3.29Å; N32-Y36 WeakPolarHBondContact CA-O 3.46Å; N32-R37 WeakPolarHBondContact OD1-CA 3.39Å; N32-M39 HydrophobicContact CB-CG 4.32Å; N32-M39 HydrophobicContact CB-SD 4.36Å; N32-M39 WeakPolarHBondContact OD1-CB 2.85Å; N32-M39 PolarHBondContact OD1-N 2.89Å
33S92Very high96.8Very high87 Ų8748 Ų4861%0.60824%0.238SC*.SBendtrans-128.4153.7179.563.70000111.6T35 Y36S33-T35 PolarHBondContact O-N 2.86Å; S33-Y36 PolarHBondContact N-O 3.33Å; S33-Y36 PolarHBondContact O-N 2.87Å
34G94Very high96.8Very high33 Ų3350 Ų5034%0.3425%0.251SS..THydrogen-bonded Turntrans59.7-120.5-178.300000111.2
35T95.2Very high96.7Very high17 Ų1750 Ų5010%0.10425%0.251CS..THydrogen-bonded Turntrans-77.3-25.1177.2-54.20000112.9S33 L153 R580 F581S33-T35 PolarHBondContact O-N 2.86Å; T35-L153 HydrophobicContact CG2-CD1 3.63Å; T35-L153 HydrophobicContact CG2-CD2 4.02Å; T35-L153 HydrophobicContact CG2-CG 4.15Å; T35-R580 HydrophobicContact CG2-CB 4.13Å; T35-F581 WeakPolarHBondContact OG1-CD2 3.46Å
36Y96.8Very high96.6Very high41 Ų4155.2 Ų55.216%0.16128%0.282CS..  trans-78.2136-175.9-57-70.3000112.1A31 N32 S33 A114 S115 H116A31-Y36 HydrophobicContact CB-CD1 4.39Å; A31-Y36 HydrophobicContact CB-CD2 4.14Å; A31-Y36 HydrophobicContact CB-CG 3.82Å; A31-Y36 CarbonylContact O-C 3.41Å; A31-Y36 WeakPolarHBondContact O-CB 3.5Å; N32-Y36 CarbonylContact C-O 3.48Å; N32-Y36 VanDerWaalsContact CA-O 3.29Å; N32-Y36 WeakPolarHBondContact CA-O 3.46Å; S33-Y36 PolarHBondContact N-O 3.33Å; S33-Y36 PolarHBondContact O-N 2.87Å; Y36-A114 WeakPolarHBondContact CE1-O 3.31Å; Y36-A114 PolarHBondContact OH-O 3.45Å; Y36-S115 WeakPolarHBondContact OH-CA 3.14Å; Y36-H116 AromaticContact CE1-ND1 3.87Å; Y36-H116 AromaticContact CE2-CE1 3.46Å; Y36-H116 VanDerWaalsContact CE2-CE1 3.46Å; Y36-H116 WeakPolarHBondContact CE2-CE1 3.24Å; Y36-H116 AromaticContact CE2-ND1 3.63Å; Y36-H116 AromaticContact CZ-CE1 3.54Å; Y36-H116 AromaticContact CZ-ND1 3.17Å; Y36-H116 PolarHBondContact OH-CE1 2.98Å; Y36-H116 PolarHBondContact OH-N 3.07Å; Y36-H116 PolarHBondContact OH-ND1 2.8Å
37R96.7Very high96.4Very high74 Ų7460.4 Ų60.428%0.27930%0.302SS..  trans-144.246.6178-58.1-171.6-170.4-1758.1111.7N32 M39 R40 W41 R580 L583N32-R37 WeakPolarHBondContact OD1-CA 3.39Å; R37-M39 PolarHBondContact O-N 3.23Å; R37-M39 VanDerWaalsContact O-N 3.15Å; R37-R40 HydrophobicContact CB-CB 4.46Å; R37-R40 WeakPolarHBondContact O-CB 3.32Å; R37-R40 PolarHBondContact O-N 3.17Å; R37-W41 WeakPolarHBondContact O-CZ3 3.39Å; R37-R580 PolarHBondContact NH2-O 2.96Å; R37-L583 VanDerWaalsContact CZ-CD1 3.45Å; R37-L583 VanDerWaalsContact NH1-CD1 3.29Å
38E98Very high96.1Very high29 Ų2965.1 Ų65.114%0.13633%0.327CS..G310 helixtrans-56.8-34.4-173.3-69.4-175.2144.800112.6K27 M30 A31 R40 W41 F42K27-E38 IonicContact NZ-OE1 2.65Å; K27-E38 PolarHBondContact NZ-OE1 3.24Å; K27-E38 IonicContact NZ-OE2 2.66Å; K27-E38 PolarHBondContact NZ-OE2 2.99Å; M30-E38 VanDerWaalsContact CA-OE2 3.3Å; M30-E38 WeakPolarHBondContact CA-OE2 3.48Å; M30-E38 HydrophobicContact CB-CB 4.13Å; M30-E38 HydrophobicContact CG-CB 4.42Å; M30-E38 HydrophobicContact SD-CB 3.85Å; M30-E38 VanDerWaalsContact SD-OE2 3.34Å; A31-E38 HydrophobicContact CB-CG 4.41Å; A31-E38 PolarHBondContact N-OE2 2.86Å; A31-E38 WeakPolarHBondContact O-CB 3.31Å; A31-E38 PolarHBondContact O-N 2.91Å; E38-R40 PolarHBondContact O-N 3.22Å; E38-R40 VanDerWaalsContact O-N 3.09Å; E38-W41 PolarHBondContact O-N 2.98Å; E38-F42 PolarHBondContact O-N 2.84Å
39M97.6Very high95.7Very high109 Ų10965.3 Ų65.354%0.53733%0.326SS..G310 helixtrans-64.9-13.1178.6-63.5-174177.100113.8M30 N32 R37 W41 F42M30-M39 HydrophobicContact CB-CE 3.94Å; M30-M39 HydrophobicContact CB-CG 3.84Å; M30-M39 HydrophobicContact CG-CG 4.25Å; N32-M39 HydrophobicContact CB-CG 4.32Å; N32-M39 HydrophobicContact CB-SD 4.36Å; N32-M39 WeakPolarHBondContact OD1-CB 2.85Å; N32-M39 PolarHBondContact OD1-N 2.89Å; R37-M39 PolarHBondContact O-N 3.23Å; R37-M39 VanDerWaalsContact O-N 3.15Å; M39-W41 PolarHBondContact O-N 2.81Å; M39-F42 WeakPolarHBondContact CA-O 3.16Å
40R98.1Very high95.6Very high190 Ų19067.2 Ų67.272%0.71733%0.334SS*.G310 helixtrans-64.4-30.8169.7-178.3176.5175.289-0.3111.9R37 E38R37-R40 HydrophobicContact CB-CB 4.46Å; R37-R40 WeakPolarHBondContact O-CB 3.32Å; R37-R40 PolarHBondContact O-N 3.17Å; E38-R40 PolarHBondContact O-N 3.22Å; E38-R40 VanDerWaalsContact O-N 3.09Å
41W98.2Very high95.6Very high140 Ų14068.2 Ų68.253%0.5334%0.341SS..THydrogen-bonded Turntrans-120.1-28.2-171.7-56.8-73.4000114R9 R37 E38 M39R9-W41 WeakPolarHBondContact CD-O 3.36Å; R9-W41 PolarHBondContact NH1-O 3.46Å; R37-W41 WeakPolarHBondContact O-CZ3 3.39Å; E38-W41 PolarHBondContact O-N 2.98Å; M39-W41 PolarHBondContact O-N 2.81Å
42F98.6Very high95.7Very high41 Ų4169.8 Ų69.818%0.1835%0.347CS..  trans-126.9149.7-170.9-57.8-71.6000112.1P2 R9 N11 M30 E38 M39P2-F42 HydrophobicContact CB-CE1 3.64Å; P2-F42 HydrophobicContact CB-CZ 4.02Å; R9-F42 HydrophobicContact CB-CD1 4.25Å; R9-F42 HydrophobicContact CG-CD1 3.67Å; R9-F42 HydrophobicContact CG-CE1 3.73Å; R9-F42 CarbonylContact O-C 3.51Å; R9-F42 WeakPolarHBondContact O-CA 3.41Å; N11-F42 HydrophobicContact CB-CD1 4.2Å; N11-F42 HydrophobicContact CB-CD2 4.24Å; N11-F42 HydrophobicContact CB-CE1 4.43Å; N11-F42 HydrophobicContact CB-CE2 4.47Å; N11-F42 HydrophobicContact CB-CG 4.1Å; M30-F42 HydrophobicContact CE-CB 3.32Å; M30-F42 HydrophobicContact CE-CG 4.38Å; M30-F42 HydrophobicContact SD-CB 4.35Å; E38-F42 PolarHBondContact O-N 2.84Å; M39-F42 WeakPolarHBondContact CA-O 3.16Å
43S98.3Very high95.9Very high53 Ų5372 Ų7237%0.37136%0.355SS..PPolyproline II helixtrans-99.1141169.2-620000110.5V8 R9 Y10 M30V8-S43 VanDerWaalsContact CG1-CB 3.44Å; V8-S43 WeakPolarHBondContact CG1-OG 3.38Å; R9-S43 PolarHBondContact O-N 2.75Å; Y10-S43 WeakPolarHBondContact CD1-O 3.48Å; M30-S43 VanDerWaalsContact CE-C 3.42Å; M30-S43 WeakPolarHBondContact CE-O 3.29Å
44P97.8Very high96.2Very high41 Ų4169.3 Ų69.327%0.26633%0.331SS..PPolyproline II helixtrans-65.9144.8168.328.1-32.7000110.3M28 M30 T46M28-P44 WeakPolarHBondContact O-CB 3.47Å; M30-P44 HydrophobicContact CG-CB 4.16Å; P44-T46 PolarHBondContact O-N 2.9Å
45W97.7Very high96.4Very high5 Ų574.6 Ų74.62%0.01935%0.345CS..PPolyproline II helixtrans-72.4122.9165-179.6-102.4000110.5Y10 P26 K27 M28 R47 E52 F71Y10-W45 HydrophobicContact CE1-CB 4.41Å; Y10-W45 AromaticContact CE1-CE3 3.95Å; Y10-W45 HydrophobicContact CE1-CE3 3.95Å; P26-W45 HydrophobicContact CB-CB 3.9Å; P26-W45 HydrophobicContact CB-CG 4.42Å; P26-W45 HydrophobicContact CG-CB 3.53Å; P26-W45 HydrophobicContact CG-CD2 3.67Å; P26-W45 HydrophobicContact CG-CE3 3.89Å; P26-W45 HydrophobicContact CG-CG 3.54Å; K27-W45 PolarHBondContact O-N 2.85Å; M28-W45 HydrophobicContact CG-CB 3.89Å; M28-W45 HydrophobicContact CG-CG 4.36Å; W45-R47 HydrophobicContact CH2-CB 4.41Å; W45-R47 HydrophobicContact CZ2-CB 3.68Å; W45-R47 HydrophobicContact CZ2-CG 4.3Å; W45-R47 PolarHBondContact NE1-O 3.3Å; W45-E52 HydrophobicContact CH2-CG 4.05Å; W45-F71 HydrophobicContact CE3-CD1 4.29Å; W45-F71 AromaticContact CE3-CE1 3.76Å; W45-F71 HydrophobicContact CE3-CE1 3.76Å; W45-F71 HydrophobicContact CH2-CD1 4.12Å; W45-F71 HydrophobicContact CH2-CE1 4.38Å; W45-F71 AromaticContact CZ3-CD1 3.81Å; W45-F71 HydrophobicContact CZ3-CD1 3.81Å; W45-F71 AromaticContact CZ3-CE1 3.62Å; W45-F71 HydrophobicContact CZ3-CE1 3.62Å
46T96.1Very high96.6Very high109 Ų10974.2 Ų74.267%0.66934%0.342SS*.  trans-105.4-11.5-173.954.30000113.9P44 L48P44-T46 PolarHBondContact O-N 2.9Å; T46-L48 PolarHBondContact O-N 3.49Å; T46-L48 VanDerWaalsContact O-N 3.14Å
47R93.6Very high96.6Very high109 Ų10975.1 Ų75.141%0.41135%0.353SS..  trans-91.273.6-177-53.2-176.1-169.9-179.713.7110.4W45 Q50 E52W45-R47 HydrophobicContact CH2-CB 4.41Å; W45-R47 HydrophobicContact CZ2-CB 3.68Å; W45-R47 HydrophobicContact CZ2-CG 4.3Å; W45-R47 PolarHBondContact NE1-O 3.3Å; R47-Q50 HydrophobicContact CB-CB 4Å; R47-Q50 HydrophobicContact CB-CG 4.46Å; R47-Q50 WeakPolarHBondContact O-CB 3.16Å; R47-Q50 PolarHBondContact O-N 2.79Å; R47-E52 IonicContact CZ-OE1 3.09Å; R47-E52 VanDerWaalsContact NH1-CD 3.31Å; R47-E52 IonicContact NH1-OE1 2.69Å; R47-E52 PolarHBondContact NH1-OE1 2.86Å; R47-E52 IonicContact NH1-OE2 3.62Å; R47-E52 IonicContact NH2-OE1 3.59Å
48L91.2Very high96.7Very high101 Ų10181.1 Ų81.153%0.52938%0.376SS..THydrogen-bonded Turntrans-55.3138.6-178.2-47-178.2000110.7M28 T46 Q50M28-L48 HydrophobicContact CE-CD2 3.22Å; M28-L48 HydrophobicContact SD-CD2 4.44Å; T46-L48 PolarHBondContact O-N 3.49Å; T46-L48 VanDerWaalsContact O-N 3.14Å; L48-Q50 PolarHBondContact O-N 2.86Å
49R89Confident96.7Very high29 Ų2986 Ų8611%0.10940%0.4CS..THydrogen-bonded Turntrans5725.6-179.5-48.4-56.5-166.5-16023.8114.9D73 D104 C210R49-D73 WeakPolarHBondContact CD-OD2 3.45Å; R49-D73 PolarHBondContact N-OD2 2.75Å; R49-D73 IonicContact NH1-OD1 3.94Å; R49-D73 IonicContact NH1-OD2 3.98Å; R49-D73 PolarHBondContact NH1-OD2 3.21Å; R49-D104 IonicContact NH2-OD2 3.98Å; R49-C210 PolarHBondContact NH1-SG 2.85Å; R49-C210 PolarHBondContact NH2-SG 3.04Å
50Q93.4Very high96.7Very high91 Ų9183.3 Ų83.343%0.42539%0.388SS..  trans-126.3148.6178.1-62.217826.300110.6R47 L48 G72 D73R47-Q50 HydrophobicContact CB-CB 4Å; R47-Q50 HydrophobicContact CB-CG 4.46Å; R47-Q50 WeakPolarHBondContact O-CB 3.16Å; R47-Q50 PolarHBondContact O-N 2.79Å; L48-Q50 PolarHBondContact O-N 2.86Å; Q50-G72 WeakPolarHBondContact O-CA 3.44Å; Q50-D73 PolarHBondContact O-N 2.66Å
51V95.9Very high96.8Very high45 Ų4576.8 Ų76.827%0.27337%0.365SS..EExtended strand (participates in β ladder)trans-125146.3174.5-64.60000109.4F71 C74 H211V51-F71 CarbonylContact C-O 3.56Å; V51-F71 WeakPolarHBondContact CA-O 3.23Å; V51-C74 HydrophobicContact CG1-CB 3.64Å; V51-H211 HydrophobicContact CG1-CB 4.43Å
52E97.7Very high96.8Very high41 Ų4177.6 Ų77.619%0.19238%0.375CS..EExtended strand (participates in β ladder)trans-117.9163.2168.4-66.9-172.9129.300109.4H5 H6 W45 R47 F71H5-E52 IonicContact CD2-OE2 3.96Å; H5-E52 PolarHBondContact CD2-OE2 3.17Å; H5-E52 IonicContact CE1-OE2 3.89Å; H5-E52 IonicContact NE2-OE2 2.71Å; H5-E52 PolarHBondContact NE2-OE2 2.9Å; H6-E52 IonicContact CE1-OE1 3.73Å; H6-E52 IonicContact CE1-OE2 3.73Å; H6-E52 IonicContact ND1-OE1 3.87Å; H6-E52 IonicContact ND1-OE2 3.57Å; W45-E52 HydrophobicContact CH2-CG 4.05Å; R47-E52 IonicContact CZ-OE1 3.09Å; R47-E52 VanDerWaalsContact NH1-CD 3.31Å; R47-E52 IonicContact NH1-OE1 2.69Å; R47-E52 PolarHBondContact NH1-OE1 2.86Å; R47-E52 IonicContact NH1-OE2 3.62Å; R47-E52 IonicContact NH2-OE1 3.59Å; E52-F71 PolarHBondContact N-O 3.09Å; E52-F71 PolarHBondContact O-N 2.9Å
53E98Very high96.7Very high126 Ų12680.3 Ų80.359%0.58940%0.395SS*.EExtended strand (participates in β ladder)trans-81.1128.4168.1-64.7-166.2120.200110H5 T68H5-E53 PolarHBondContact CE1-O 2.9Å; E53-T68 HydrophobicContact CB-CG2 4.38Å; E53-T68 PolarHBondContact OE1-OG1 3.24Å
54Y98.5Very high96.7Very high31 Ų3178.5 Ų78.512%0.12238%0.381CS..EExtended strand (participates in β ladder)trans-105.4119.8171.5174.6-93.3000109.7I3 M4 H5 I24 L56 T68 V69 F71I3-Y54 HydrophobicContact CG2-CD2 4.27Å; I3-Y54 HydrophobicContact CG2-CE2 3.5Å; M4-Y54 WeakPolarHBondContact O-CE2 3.44Å; H5-Y54 HydrophobicContact CB-CD2 4.05Å; H5-Y54 HydrophobicContact CB-CE2 4.31Å; H5-Y54 AromaticContact ND1-CD2 3.55Å; I24-Y54 HydrophobicContact CD1-CD1 3.44Å; I24-Y54 VanDerWaalsContact CD1-CD1 3.44Å; I24-Y54 HydrophobicContact CD1-CE1 3.83Å; I24-Y54 HydrophobicContact CD1-CG 3.98Å; Y54-L56 HydrophobicContact CD1-CD2 4.01Å; Y54-L56 HydrophobicContact CE1-CD2 3.99Å; Y54-L56 PolarHBondContact O-N 2.87Å; Y54-T68 CarbonylContact O-C 3.49Å; Y54-T68 WeakPolarHBondContact O-CA 3.47Å; Y54-V69 HydrophobicContact CD1-CG2 3.96Å; Y54-V69 PolarHBondContact N-O 3.49Å; Y54-V69 PolarHBondContact O-N 2.95Å; Y54-F71 HydrophobicContact CD2-CD2 4.11Å; Y54-F71 HydrophobicContact CG-CD2 4.26Å
55F98.5Very high96.7Very high145 Ų14579.3 Ų79.364%0.63640%0.398SS*.EExtended strand (participates in β ladder)trans-70.7119.7173-75.3-88.1000110.3T68F55-T68 HydrophobicContact CD1-CG2 3.67Å; F55-T68 HydrophobicContact CD2-CG2 4.37Å; F55-T68 HydrophobicContact CE1-CG2 3.64Å; F55-T68 HydrophobicContact CE2-CG2 4.34Å; F55-T68 HydrophobicContact CG-CG2 4.05Å; F55-T68 HydrophobicContact CZ-CG2 3.99Å
56L98.5Very high96.8Very high8 Ų880.9 Ų80.94%0.04241%0.405CS..PPolyproline II helixtrans-70.8146179-71.2173.8000110.8I21 Y54 I60 Q61 Q66 D67 V69I21-L56 HydrophobicContact CD1-CD1 4.3Å; I21-L56 HydrophobicContact CD1-CD2 3.65Å; Y54-L56 HydrophobicContact CD1-CD2 4.01Å; Y54-L56 HydrophobicContact CE1-CD2 3.99Å; Y54-L56 PolarHBondContact O-N 2.87Å; L56-I60 HydrophobicContact CB-CB 4.35Å; L56-I60 HydrophobicContact CB-CG2 4.39Å; L56-I60 HydrophobicContact CD1-CG2 4.04Å; L56-I60 HydrophobicContact CD2-CG2 4.04Å; L56-I60 HydrophobicContact CG-CG2 4.4Å; L56-Q61 HydrophobicContact CB-CG 3.87Å; L56-Q61 PolarHBondContact O-NE2 3.27Å; L56-Q66 HydrophobicContact CD1-CB 3.74Å; L56-Q66 WeakPolarHBondContact CD1-O 3.48Å; L56-D67 PolarHBondContact N-O 2.93Å; L56-V69 HydrophobicContact CD1-CG1 3.62Å; L56-V69 HydrophobicContact CD2-CG1 4.19Å; L56-V69 HydrophobicContact CD2-CG2 3.79Å; L56-V69 HydrophobicContact CG-CG1 4.02Å; L56-V69 HydrophobicContact CG-CG2 4.15Å
57P98.1Very high96.9Very high60 Ų6080.9 Ų80.939%0.3940%0.401SS..PPolyproline II helixtrans-58.6145.6169.1-22.733.4000111.1M59 I60 Q61P57-M59 HydrophobicContact CB-CG 4.15Å; P57-M59 PolarHBondContact O-N 3.14Å; P57-M59 VanDerWaalsContact O-N 3.11Å; P57-I60 HydrophobicContact CB-CG1 4.36Å; P57-I60 HydrophobicContact CG-CG1 4.35Å; P57-I60 WeakPolarHBondContact O-CA 3.49Å; P57-I60 WeakPolarHBondContact O-CB 3.43Å; P57-I60 PolarHBondContact O-N 3.47Å; P57-Q61 PolarHBondContact O-N 2.77Å
58R98.3Very high97.1Very high200 Ų20077.5 Ų77.576%0.75539%0.392SS*.Hα-helixtrans-48.4-44-179-68.7-177-177.21730.3113.3I60 Q61 E62R58-I60 PolarHBondContact O-N 3.38Å; R58-Q61 WeakPolarHBondContact O-CB 3.13Å; R58-Q61 PolarHBondContact O-N 3Å; R58-Q61 VanDerWaalsContact O-N 3.08Å; R58-E62 WeakPolarHBondContact O-CG 3.42Å; R58-E62 PolarHBondContact O-N 3.45Å
59M98.3Very high97.5Very high131 Ų13172.9 Ų72.965%0.64537%0.368SS*.Hα-helixtrans-58.6-29.8177.467.9178.1-6500113.8P57 V63P57-M59 HydrophobicContact CB-CG 4.15Å; P57-M59 PolarHBondContact O-N 3.14Å; P57-M59 VanDerWaalsContact O-N 3.11Å; M59-V63 WeakPolarHBondContact O-CG2 3.16Å
60I98.3Very high97.9Very high53 Ų5373.2 Ų73.227%0.27237%0.374SS..Hα-helixtrans-84.6-40.3176.2-55.6-56.4000109.6I21 L56 P57 R58 E62 V63 T64I21-I60 HydrophobicContact CD1-CG2 3.68Å; L56-I60 HydrophobicContact CB-CB 4.35Å; L56-I60 HydrophobicContact CB-CG2 4.39Å; L56-I60 HydrophobicContact CD1-CG2 4.04Å; L56-I60 HydrophobicContact CD2-CG2 4.04Å; L56-I60 HydrophobicContact CG-CG2 4.4Å; P57-I60 HydrophobicContact CB-CG1 4.36Å; P57-I60 HydrophobicContact CG-CG1 4.35Å; P57-I60 WeakPolarHBondContact O-CA 3.49Å; P57-I60 WeakPolarHBondContact O-CB 3.43Å; P57-I60 PolarHBondContact O-N 3.47Å; R58-I60 PolarHBondContact O-N 3.38Å; I60-E62 VanDerWaalsContact C-N 3.28Å; I60-E62 PolarHBondContact O-N 3.39Å; I60-V63 PolarHBondContact O-N 2.76Å; I60-V63 VanDerWaalsContact O-N 3.09Å; I60-T64 HydrophobicContact CG2-CG2 3.64Å; I60-T64 WeakPolarHBondContact O-CB 3.14Å; I60-T64 WeakPolarHBondContact O-CG2 3.19Å; I60-T64 PolarHBondContact O-N 3.01Å; I60-T64 PolarHBondContact O-OG1 2.72Å
61Q98.5Very high98.2Very high53 Ų5368.9 Ų68.925%0.24835%0.354CS..Hα-helixtrans-56-43.1174.8-58.3-178.8-8.100111.7L56 P57 R58 V63 G65 Q66L56-Q61 HydrophobicContact CB-CG 3.87Å; L56-Q61 PolarHBondContact O-NE2 3.27Å; P57-Q61 PolarHBondContact O-N 2.77Å; R58-Q61 WeakPolarHBondContact O-CB 3.13Å; R58-Q61 PolarHBondContact O-N 3Å; R58-Q61 VanDerWaalsContact O-N 3.08Å; Q61-V63 VanDerWaalsContact C-N 3.27Å; Q61-V63 PolarHBondContact O-N 2.75Å; Q61-G65 WeakPolarHBondContact O-CA 3.11Å; Q61-G65 PolarHBondContact O-N 2.98Å; Q61-Q66 WeakPolarHBondContact CG-O 3.17Å
62E98Very high98.2Very high158 Ų15866.7 Ų66.774%0.73834%0.341SS*.Hα-helixtrans-60.8-34.9177.5-73.7168.7-16300112.7R58 I60R58-E62 WeakPolarHBondContact O-CG 3.42Å; R58-E62 PolarHBondContact O-N 3.45Å; I60-E62 VanDerWaalsContact C-N 3.28Å; I60-E62 PolarHBondContact O-N 3.39Å
63V97.9Very high98.2Very high98 Ų9864.9 Ų64.959%0.59433%0.332SS*.Hα-helixtrans-84.8-42-178.9174.90000111.9M59 I60 Q61M59-V63 WeakPolarHBondContact O-CG2 3.16Å; I60-V63 PolarHBondContact O-N 2.76Å; I60-V63 VanDerWaalsContact O-N 3.09Å; Q61-V63 VanDerWaalsContact C-N 3.27Å; Q61-V63 PolarHBondContact O-N 2.75Å
64T98Very high98Very high14 Ų1458.9 Ų58.99%0.08631%0.305CS..Hα-helixtrans-92.4-23.2-172.768.10000112.5R19 K20 I60 Q66R19-T64 VanDerWaalsContact O-CA 3.29Å; R19-T64 WeakPolarHBondContact O-CA 3.5Å; R19-T64 VanDerWaalsContact O-CB 3.27Å; R19-T64 WeakPolarHBondContact O-CB 3.24Å; R19-T64 VanDerWaalsContact O-CG2 3.29Å; R19-T64 WeakPolarHBondContact O-CG2 3.46Å; K20-T64 VanDerWaalsContact CD-O 3.29Å; K20-T64 WeakPolarHBondContact CD-O 3.35Å; K20-T64 WeakPolarHBondContact CE-O 3.34Å; K20-T64 PolarHBondContact NZ-O 2.71Å; I60-T64 HydrophobicContact CG2-CG2 3.64Å; I60-T64 WeakPolarHBondContact O-CB 3.14Å; I60-T64 WeakPolarHBondContact O-CG2 3.19Å; I60-T64 PolarHBondContact O-N 3.01Å; I60-T64 PolarHBondContact O-OG1 2.72Å; T64-Q66 VanDerWaalsContact C-N 3.25Å; T64-Q66 PolarHBondContact O-N 2.97Å; T64-Q66 PolarHBondContact OG1-N 3.21Å
65G98.3Very high97.9Very high59 Ų5957.5 Ų57.561%0.60830%0.299SS*.  trans59.735.2-168.300000112.5K20 Q61K20-G65 PolarHBondContact NZ-O 2.85Å; K20-G65 VanDerWaalsContact NZ-O 3.16Å; Q61-G65 WeakPolarHBondContact O-CA 3.11Å; Q61-G65 PolarHBondContact O-N 2.98Å
66Q98.4Very high97.9Very high37 Ų3751.1 Ų51.117%0.17327%0.272CS..  trans-122.7129.4175-63.7173.9-87.500108.9K20 I21 L56 Q61 T64K20-Q66 VanDerWaalsContact CA-OE1 3.26Å; K20-Q66 HydrophobicContact CD-CG 3.59Å; I21-Q66 PolarHBondContact O-NE2 2.66Å; L56-Q66 HydrophobicContact CD1-CB 3.74Å; L56-Q66 WeakPolarHBondContact CD1-O 3.48Å; Q61-Q66 WeakPolarHBondContact CG-O 3.17Å; T64-Q66 VanDerWaalsContact C-N 3.25Å; T64-Q66 PolarHBondContact O-N 2.97Å; T64-Q66 PolarHBondContact OG1-N 3.21Å
67D98.4Very high97.9Very high110 Ų11052.1 Ų52.159%0.58828%0.279SS*.SBendtrans-78.8-43.9174-61.5-42.9000111.2L56L56-D67 PolarHBondContact N-O 2.93Å
68T98.6Very high97.9Very high37 Ų3750 Ų5023%0.22727%0.266CS..EExtended strand (participates in β ladder)trans-129159-178.364.90000112.1E53 Y54 F55E53-T68 HydrophobicContact CB-CG2 4.38Å; E53-T68 PolarHBondContact OE1-OG1 3.24Å; Y54-T68 CarbonylContact O-C 3.49Å; Y54-T68 WeakPolarHBondContact O-CA 3.47Å; F55-T68 HydrophobicContact CD1-CG2 3.67Å; F55-T68 HydrophobicContact CD2-CG2 4.37Å; F55-T68 HydrophobicContact CE1-CG2 3.64Å; F55-T68 HydrophobicContact CE2-CG2 4.34Å; F55-T68 HydrophobicContact CG-CG2 4.05Å; F55-T68 HydrophobicContact CZ-CG2 3.99Å
69V98.4Very high97.8Very high4 Ų447.6 Ų47.62%0.02426%0.26CS..EExtended strand (participates in β ladder)trans-140.9156.3173-64.20000111.1I21 I24 Y54 L56 F71I21-V69 HydrophobicContact CB-CG1 3.83Å; I21-V69 HydrophobicContact CG2-CB 4.06Å; I21-V69 HydrophobicContact CG2-CG1 3.82Å; I21-V69 HydrophobicContact CG2-CG2 4.06Å; I24-V69 HydrophobicContact CD1-CG2 3.5Å; I24-V69 HydrophobicContact CG1-CG2 3.98Å; Y54-V69 HydrophobicContact CD1-CG2 3.96Å; Y54-V69 PolarHBondContact N-O 3.49Å; Y54-V69 PolarHBondContact O-N 2.95Å; L56-V69 HydrophobicContact CD1-CG1 3.62Å; L56-V69 HydrophobicContact CD2-CG1 4.19Å; L56-V69 HydrophobicContact CD2-CG2 3.79Å; L56-V69 HydrophobicContact CG-CG1 4.02Å; L56-V69 HydrophobicContact CG-CG2 4.15Å; V69-F71 PolarHBondContact O-N 3.45Å
70P98.3Very high97.7Very high36 Ų3643.2 Ų43.223%0.23424%0.24CC..EExtended strand (participates in β ladder)trans-62.3133.1173.5-20.932.5000112.2L23 I24 I213L23-P70 HydrophobicContact CD1-CB 4.25Å; I24-P70 PolarHBondContact N-O 2.57Å; P70-I213 HydrophobicContact CB-CD1 3.91Å; P70-I213 HydrophobicContact CB-CG1 4.47Å; P70-I213 HydrophobicContact CG-CD1 3.65Å; P70-I213 HydrophobicContact CG-CG1 4.34Å
71F98.6Very high97.6Very high0 Ų041.2 Ų41.20%023%0.23CC..EExtended strand (participates in β ladder)trans-128.9116.8175.2-175.3-77.9000110.4I3 H5 Y10 I24 P26 W45 V51 E52 Y54 V69I3-F71 HydrophobicContact CG2-CE2 3.95Å; H5-F71 HydrophobicContact CB-CD1 4.39Å; H5-F71 HydrophobicContact CB-CD2 4.36Å; H5-F71 HydrophobicContact CB-CE1 3.96Å; H5-F71 HydrophobicContact CB-CE2 3.93Å; H5-F71 HydrophobicContact CB-CZ 3.72Å; H5-F71 AromaticContact CD2-CD1 3.55Å; H5-F71 AromaticContact CD2-CE1 3.66Å; Y10-F71 HydrophobicContact CD2-CE1 4.07Å; Y10-F71 AromaticContact CD2-CZ 3.55Å; Y10-F71 HydrophobicContact CD2-CZ 3.55Å; Y10-F71 HydrophobicContact CE2-CE1 4.17Å; Y10-F71 HydrophobicContact CE2-CZ 4.09Å; Y10-F71 HydrophobicContact CG-CE1 4.41Å; Y10-F71 AromaticContact CG-CZ 3.86Å; Y10-F71 HydrophobicContact CG-CZ 3.86Å; I24-F71 HydrophobicContact CB-CD2 3.69Å; I24-F71 HydrophobicContact CB-CE2 4.34Å; I24-F71 HydrophobicContact CB-CG 4.45Å; I24-F71 HydrophobicContact CD1-CD2 4.4Å; I24-F71 HydrophobicContact CG2-CD2 3.35Å; I24-F71 HydrophobicContact CG2-CE2 3.49Å; I24-F71 VanDerWaalsContact CG2-CE2 3.49Å; I24-F71 HydrophobicContact CG2-CG 4.41Å; I24-F71 VanDerWaalsContact O-CA 3.29Å; I24-F71 WeakPolarHBondContact O-CA 3.28Å; P26-F71 HydrophobicContact CB-CE1 3.93Å; P26-F71 HydrophobicContact CB-CZ 3.75Å; P26-F71 HydrophobicContact CG-CD1 4.19Å; P26-F71 HydrophobicContact CG-CE1 3.59Å; P26-F71 HydrophobicContact CG-CZ 3.91Å; W45-F71 HydrophobicContact CE3-CD1 4.29Å; W45-F71 AromaticContact CE3-CE1 3.76Å; W45-F71 HydrophobicContact CE3-CE1 3.76Å; W45-F71 HydrophobicContact CH2-CD1 4.12Å; W45-F71 HydrophobicContact CH2-CE1 4.38Å; W45-F71 AromaticContact CZ3-CD1 3.81Å; W45-F71 HydrophobicContact CZ3-CD1 3.81Å; W45-F71 AromaticContact CZ3-CE1 3.62Å; W45-F71 HydrophobicContact CZ3-CE1 3.62Å; V51-F71 CarbonylContact C-O 3.56Å; V51-F71 WeakPolarHBondContact CA-O 3.23Å; E52-F71 PolarHBondContact N-O 3.09Å; E52-F71 PolarHBondContact O-N 2.9Å; Y54-F71 HydrophobicContact CD2-CD2 4.11Å; Y54-F71 HydrophobicContact CG-CD2 4.26Å; V69-F71 PolarHBondContact O-N 3.45Å
72G97.6Very high97.6Very high0 Ų038.9 Ų38.90%022%0.22CC..EExtended strand (participates in β ladder)trans149.6-156.5178.200000114.4I24 R25 Q50I24-G72 PolarHBondContact O-N 2.96Å; R25-G72 WeakPolarHBondContact CD-O 3.34Å; Q50-G72 WeakPolarHBondContact O-CA 3.44Å
73D96.5Very high97.6Very high2 Ų232.6 Ų32.61%0.01119%0.191CC..SBendtrans-96.897.6-176.9-178.138.9000111.1R25 M28 R49 Q50R25-D73 IonicContact NE-OD1 3.57Å; R25-D73 PolarHBondContact NE-OD1 3.15Å; R25-D73 IonicContact NH2-OD1 3.12Å; M28-D73 HydrophobicContact SD-CB 3.74Å; M28-D73 VanDerWaalsContact SD-CG 3.51Å; R49-D73 WeakPolarHBondContact CD-OD2 3.45Å; R49-D73 PolarHBondContact N-OD2 2.75Å; R49-D73 IonicContact NH1-OD1 3.94Å; R49-D73 IonicContact NH1-OD2 3.98Å; R49-D73 PolarHBondContact NH1-OD2 3.21Å; Q50-D73 PolarHBondContact O-N 2.66Å
74C94.3Very high97.5Very high1 Ų128 Ų281%0.00716%0.163CC..EExtended strand (participates in β ladder)trans-152.5172.6179.366.20000111.5L23 V51 H211L23-C74 WeakPolarHBondContact CD1-SG 3.31Å; L23-C74 WeakPolarHBondContact CD2-SG 3.36Å; V51-C74 HydrophobicContact CG1-CB 3.64Å; C74-H211 WeakPolarHBondContact CA-O 3.41Å; C74-H211 HydrophobicContact CB-CB 3.8Å; C74-H211 WeakPolarHBondContact CB-O 3.48Å
75V97.1Very high97.5Very high2 Ų227.5 Ų27.51%0.01216%0.16CC..EExtended strand (participates in β ladder)trans-120.6156.5-178-55.50000110.8M101 V106 C210 H211 R212 I213V75-M101 HydrophobicContact CG1-CG 4.37Å; V75-V106 HydrophobicContact CB-CG2 4.25Å; V75-V106 HydrophobicContact CG1-CG2 3.84Å; V75-V106 HydrophobicContact CG2-CG2 4.38Å; V75-C210 HydrophobicContact CG1-CB 4.2Å; V75-C210 HydrophobicContact CG2-CB 4.05Å; V75-H211 PolarHBondContact N-O 3.39Å; V75-R212 HydrophobicContact CG2-CG 3.75Å; V75-R212 WeakPolarHBondContact O-CA 3.43Å; V75-I213 PolarHBondContact O-N 2.93Å
76L98.1Very high97.4Very high11 Ų1124.8 Ų24.86%0.05813%0.131CC..EExtended strand (participates in β ladder)trans-89.5137.9172-57.3-173.8000109.5L15 L22 L23 S82 I83 I213 V215L15-L76 HydrophobicContact CB-CD1 4.29Å; L15-L76 HydrophobicContact CD2-CD1 3.56Å; L15-L76 HydrophobicContact CD2-CG 4.15Å; L22-L76 HydrophobicContact CB-CD2 4.15Å; L22-L76 HydrophobicContact CD1-CD1 4.02Å; L23-L76 HydrophobicContact CB-CD2 4.09Å; L23-L76 HydrophobicContact CD2-CD2 4.32Å; L76-S82 CarbonylContact O-C 3.23Å; L76-S82 VanDerWaalsContact O-CA 3.23Å; L76-S82 WeakPolarHBondContact O-CA 3.46Å; L76-S82 WeakPolarHBondContact O-CB 3.49Å; L76-I83 HydrophobicContact CB-CB 4.37Å; L76-I83 PolarHBondContact N-O 3.22Å; L76-I83 PolarHBondContact O-N 3.09Å; L76-I213 HydrophobicContact CD2-CB 3.88Å; L76-I213 HydrophobicContact CD2-CG1 4.46Å; L76-I213 HydrophobicContact CD2-CG2 4.2Å; L76-V215 HydrophobicContact CB-CG2 4.17Å; L76-V215 HydrophobicContact CD2-CG2 4.14Å
77S97.9Very high97.3Very high28 Ų2823.2 Ų23.220%0.19612%0.124CC..EExtended strand (participates in β ladder)trans-120.8110.8173.1-1620000107.9I213 V215S77-I213 PolarHBondContact N-O 3.04Å; S77-V215 PolarHBondContact O-N 2.77Å
78T97.9Very high97.2Very high17 Ų1718.3 Ų18.310%0.10410%0.098CC..  trans-87.5-173.8173.564.40000109.3D80 T81 V215 F217 L219T78-D80 WeakPolarHBondContact CB-OD1 3.3Å; T78-D80 PolarHBondContact O-N 2.87Å; T78-D80 PolarHBondContact OG1-OD1 3.06Å; T78-T81 PolarHBondContact N-O 3.44Å; T78-T81 WeakPolarHBondContact OG1-CG2 3.44Å; T78-T81 PolarHBondContact OG1-N 3.48Å; T78-T81 PolarHBondContact OG1-O 2.75Å; T78-T81 VanDerWaalsContact OG1-O 3.06Å; T78-V215 HydrophobicContact CG2-CB 4.29Å; T78-F217 WeakPolarHBondContact CB-O 3.27Å; T78-L219 HydrophobicContact CG2-CD1 3.6Å
79K96.7Very high97Very high148 Ų14817 Ų1764%0.6439%0.091SC*.SBendtrans-67.6-27.3175.8-72179.5176.7162.90113D216 F217K79-D216 WeakPolarHBondContact CE-OD1 3.14Å; K79-D216 IonicContact NZ-OD1 3.45Å; K79-D216 PolarHBondContact NZ-OD1 2.76Å; K79-F217 PolarHBondContact N-O 3.46Å
80D95.7Very high96.9Very high40 Ų4016.8 Ų16.821%0.2149%0.09CC..SBendtrans-122.8-15.9-166.156.2-15.3000114.3T78 S218 L219 S220T78-D80 WeakPolarHBondContact CB-OD1 3.3Å; T78-D80 PolarHBondContact O-N 2.87Å; T78-D80 PolarHBondContact OG1-OD1 3.06Å; D80-S218 PolarHBondContact OD2-OG 3.35Å; D80-L219 PolarHBondContact OD1-N 2.91Å; D80-L219 WeakPolarHBondContact OD2-CA 3.21Å; D80-L219 PolarHBondContact OD2-N 3.22Å; D80-S220 PolarHBondContact OD2-N 2.91Å; D80-S220 PolarHBondContact OD2-OG 3.03Å
81T96.8Very high96.8Very high10 Ų1015.3 Ų15.36%0.0618%0.08CC..  trans-155.7-180179.6-169.70000112.8T78 I83 E107 I108 L188 L219T78-T81 PolarHBondContact N-O 3.44Å; T78-T81 WeakPolarHBondContact OG1-CG2 3.44Å; T78-T81 PolarHBondContact OG1-N 3.48Å; T78-T81 PolarHBondContact OG1-O 2.75Å; T78-T81 VanDerWaalsContact OG1-O 3.06Å; T81-I83 HydrophobicContact CG2-CG1 4.3Å; T81-E107 WeakPolarHBondContact CA-OE2 3.33Å; T81-E107 VanDerWaalsContact CB-OE2 3.28Å; T81-E107 WeakPolarHBondContact CB-OE2 3.29Å; T81-E107 PolarHBondContact OG1-OE2 3.03Å; T81-I108 HydrophobicContact CG2-CD1 4.04Å; T81-L188 HydrophobicContact CG2-CD1 4.43Å; T81-L219 HydrophobicContact CG2-CD1 4.24Å; T81-L219 HydrophobicContact CG2-CD2 3.98Å; T81-L219 HydrophobicContact CG2-CG 4.49Å
82S97.3Very high96.4Very high5 Ų520.9 Ų20.94%0.03510%0.101CC..EExtended strand (participates in β ladder)trans-132.3138.6168.656.30000112.9L76 G105 V106 E107 I108L76-S82 CarbonylContact O-C 3.23Å; L76-S82 VanDerWaalsContact O-CA 3.23Å; L76-S82 WeakPolarHBondContact O-CA 3.46Å; L76-S82 WeakPolarHBondContact O-CB 3.49Å; S82-G105 PolarHBondContact OG-O 3.45Å; S82-G105 VanDerWaalsContact OG-O 3.09Å; S82-V106 WeakPolarHBondContact OG-CA 3.36Å; S82-E107 PolarHBondContact O-N 3.25Å; S82-I108 PolarHBondContact O-N 2.99Å; S82-I108 VanDerWaalsContact O-N 3.15Å
83I98.3Very high96.1Very high26 Ų2623.7 Ų23.713%0.13312%0.116CC..EExtended strand (participates in β ladder)trans-121.2122-169.9-49174.3000109.7L76 T81 I108 T110 L219L76-I83 HydrophobicContact CB-CB 4.37Å; L76-I83 PolarHBondContact N-O 3.22Å; L76-I83 PolarHBondContact O-N 3.09Å; T81-I83 HydrophobicContact CG2-CG1 4.3Å; I83-I108 CarbonylContact C-O 3.58Å; I83-I108 WeakPolarHBondContact CA-O 3.47Å; I83-I108 HydrophobicContact CG1-CB 4.25Å; I83-I108 HydrophobicContact CG1-CD1 4.4Å; I83-I108 HydrophobicContact CG2-CB 4.36Å; I83-I108 HydrophobicContact CG2-CG2 4.29Å; I83-T110 HydrophobicContact CG2-CG2 4.07Å; I83-L219 HydrophobicContact CD1-CD1 4.18Å; I83-L219 HydrophobicContact CD1-CD2 3.91Å
84G97.3Very high95.8Very high0 Ų029.6 Ų29.60%016%0.155CC..EExtended strand (participates in β ladder)trans-103.8159.817300000112.3V106 I108 T110G84-V106 VanDerWaalsContact N-CG1 3.31Å; G84-I108 PolarHBondContact N-O 3.03Å; G84-T110 PolarHBondContact O-N 2.93Å; G84-T110 PolarHBondContact O-OG1 3.45Å
85T96.4Very high95.6Very high5 Ų534.2 Ų34.23%0.03118%0.179CC..EExtended strand (participates in β ladder)trans-127.3125.2177.8-58.40000110.7R13 R25 I87 M101 T110R13-T85 HydrophobicContact CB-CG2 4.19Å; R13-T85 HydrophobicContact CG-CG2 3.82Å; R25-T85 HydrophobicContact CG-CG2 4.42Å; R25-T85 PolarHBondContact NH2-O 3.09Å; T85-I87 HydrophobicContact CG2-CG1 4.24Å; T85-M101 WeakPolarHBondContact O-CE 3.21Å; T85-T110 WeakPolarHBondContact CA-O 3.44Å; T85-T110 PolarHBondContact OG1-OG1 3Å
86E96.5Very high95.4Very high1 Ų134.2 Ų34.21%0.00518%0.18CC..EExtended strand (participates in β ladder)trans-111.3150.7169.3-160.1167.879.900108.1E90 L91 P97 H98 T110 N111 Y140E86-E90 WeakPolarHBondContact CA-OE2 3.37Å; E86-E90 HydrophobicContact CG-CB 3.42Å; E86-E90 VanDerWaalsContact CG-CB 3.42Å; E86-L91 WeakPolarHBondContact OE1-CA 3.44Å; E86-L91 VanDerWaalsContact OE1-CB 3.23Å; E86-L91 WeakPolarHBondContact OE1-CB 3.28Å; E86-P97 HydrophobicContact CG-CB 4.41Å; E86-P97 HydrophobicContact CG-CG 4.22Å; E86-P97 WeakPolarHBondContact OE2-CD 3.3Å; E86-H98 IonicContact OE1-ND1 2.87Å; E86-H98 IonicContact OE2-CG 3.65Å; E86-H98 PolarHBondContact OE2-N 3.21Å; E86-H98 IonicContact OE2-ND1 3.82Å; E86-H98 PolarHBondContact OE2-ND1 3.08Å; E86-T110 PolarHBondContact N-O 3.05Å; E86-N111 HydrophobicContact CB-CB 4.44Å; E86-N111 VanDerWaalsContact O-CA 3.3Å; E86-N111 WeakPolarHBondContact O-CA 3.46Å; E86-Y140 PolarHBondContact OE1-OH 3.09Å
87I97.7Very high95.3Very high4 Ų434.3 Ų34.32%0.02118%0.181CC..EExtended strand (participates in β ladder)trans-127.2107.8-178.6-52.5175.3000109.9R13 K27 T85 A89 E90R13-I87 HydrophobicContact CG-CD1 3.58Å; R13-I87 HydrophobicContact CG-CG1 3.81Å; K27-I87 HydrophobicContact CB-CB 4.44Å; K27-I87 HydrophobicContact CB-CD1 3.9Å; K27-I87 HydrophobicContact CB-CG2 4.44Å; K27-I87 HydrophobicContact CD-CB 4.2Å; K27-I87 HydrophobicContact CD-CG2 3.76Å; K27-I87 WeakPolarHBondContact CE-O 3.44Å; K27-I87 HydrophobicContact CG-CB 3.99Å; K27-I87 HydrophobicContact CG-CD1 4.38Å; K27-I87 HydrophobicContact CG-CG2 4.07Å; T85-I87 HydrophobicContact CG2-CG1 4.24Å; I87-A89 PolarHBondContact O-N 2.7Å; I87-E90 PolarHBondContact N-OE2 2.66Å; I87-E90 PolarHBondContact O-N 3.26Å; I87-E90 VanDerWaalsContact O-N 3.11Å
88C95.5Very high95.1Very high7 Ų733.6 Ų33.65%0.04717%0.174CC..G310 helixtrans50.4-110.6171-167.70000112.1E90 L91 N111 S112 S113C88-E90 PolarHBondContact O-N 3.3Å; C88-L91 WeakPolarHBondContact O-CB 3.35Å; C88-L91 PolarHBondContact O-N 2.88Å; C88-L91 VanDerWaalsContact O-N 3.09Å; C88-N111 WeakPolarHBondContact CA-OD1 3.44Å; C88-N111 PolarHBondContact N-OD1 3.02Å; C88-N111 PolarHBondContact O-ND2 2.74Å; C88-S112 PolarHBondContact N-O 2.93Å; C88-S112 VanDerWaalsContact N-O 3.16Å; C88-S113 WeakPolarHBondContact CA-OG 3.36Å
89A94.3Very high94.8Very high9 Ų934.3 Ų34.37%0.07418%0.177CC..G310 helixtrans-62.4-8.8-177.200000116.2A31 I87 L91 W92A31-A89 HydrophobicContact CB-CB 4.05Å; I87-A89 PolarHBondContact O-N 2.7Å; A89-L91 PolarHBondContact O-N 3.44Å; A89-W92 VanDerWaalsContact CA-CE2 3.46Å; A89-W92 VanDerWaalsContact CA-CH2 3.48Å; A89-W92 HydrophobicContact CB-CH2 3.97Å; A89-W92 HydrophobicContact CB-CZ2 3.35Å
90E96.7Very high94.5Very high0 Ų029 Ų290%016%0.155CC..G310 helixtrans-61.3-24.8168.5-73.5178.7-174.400112.4R25 K27 M28 L29 E86 I87 C88 S96 P97R25-E90 IonicContact CZ-OE1 3.97Å; R25-E90 IonicContact CZ-OE2 3.35Å; R25-E90 IonicContact NH1-OE1 2.77Å; R25-E90 PolarHBondContact NH1-OE1 3.19Å; R25-E90 IonicContact NH1-OE2 3.33Å; R25-E90 IonicContact NH2-OE1 3.17Å; R25-E90 IonicContact NH2-OE2 2.57Å; R25-E90 PolarHBondContact NH2-OE2 3.34Å; K27-E90 WeakPolarHBondContact CA-OE1 3.48Å; M28-E90 PolarHBondContact N-OE1 2.81Å; L29-E90 HydrophobicContact CB-CG 3.81Å; L29-E90 HydrophobicContact CD1-CB 4.48Å; L29-E90 HydrophobicContact CD1-CG 4.18Å; L29-E90 HydrophobicContact CG-CG 4.23Å; E86-E90 WeakPolarHBondContact CA-OE2 3.37Å; E86-E90 HydrophobicContact CG-CB 3.42Å; E86-E90 VanDerWaalsContact CG-CB 3.42Å; I87-E90 PolarHBondContact N-OE2 2.66Å; I87-E90 PolarHBondContact O-N 3.26Å; I87-E90 VanDerWaalsContact O-N 3.11Å; C88-E90 PolarHBondContact O-N 3.3Å; E90-S96 WeakPolarHBondContact O-CB 3.37Å; E90-S96 PolarHBondContact O-OG 3.41Å; E90-P97 HydrophobicContact CB-CG 3.96Å; E90-P97 HydrophobicContact CG-CG 4.23Å; E90-P97 WeakPolarHBondContact O-CD 3.1Å
91L96.1Very high94.4Very high6 Ų627.1 Ų27.13%0.03114%0.144CC..THydrogen-bonded Turntrans-65.8-44.3-177.7170.260.5000114.9E86 C88 A89 S96 L128 I129 A132 Y140E86-L91 WeakPolarHBondContact OE1-CA 3.44Å; E86-L91 VanDerWaalsContact OE1-CB 3.23Å; E86-L91 WeakPolarHBondContact OE1-CB 3.28Å; C88-L91 WeakPolarHBondContact O-CB 3.35Å; C88-L91 PolarHBondContact O-N 2.88Å; C88-L91 VanDerWaalsContact O-N 3.09Å; A89-L91 PolarHBondContact O-N 3.44Å; L91-S96 VanDerWaalsContact C-OG 3.24Å; L91-S96 PolarHBondContact O-OG 3.28Å; L91-L128 HydrophobicContact CD2-CB 4.13Å; L91-L128 HydrophobicContact CG-CB 4.32Å; L91-I129 HydrophobicContact CD2-CD1 4.48Å; L91-I129 HydrophobicContact CD2-CG1 3.73Å; L91-A132 HydrophobicContact CD1-CB 4.19Å; L91-Y140 HydrophobicContact CD1-CE2 4.23Å
92W90.6Very high94.2Very high116 Ų11627.1 Ų27.144%0.43915%0.146SC..THydrogen-bonded Turntrans-100.520-171.855.381.8000113.2A89 L128A89-W92 VanDerWaalsContact CA-CE2 3.46Å; A89-W92 VanDerWaalsContact CA-CH2 3.48Å; A89-W92 HydrophobicContact CB-CH2 3.97Å; A89-W92 HydrophobicContact CB-CZ2 3.35Å; W92-L128 HydrophobicContact CB-CD1 3.87Å; W92-L128 HydrophobicContact CB-CD2 4.21Å
93N90.6Very high93.8Very high59 Ų5930.8 Ų30.832%0.31617%0.165SC..SBendtrans-80.5146.7172.9-164.8-75.4000110.3L29 N95 S96L29-N93 HydrophobicContact CD1-CB 3.59Å; N93-N95 PolarHBondContact O-N 2.77Å; N93-N95 VanDerWaalsContact O-N 3.13Å; N93-N95 PolarHBondContact OD1-N 2.76Å; N93-N95 VanDerWaalsContact OD1-N 3.12Å; N93-S96 PolarHBondContact N-OG 2.79Å; N93-S96 PolarHBondContact O-N 3.14Å; N93-S96 PolarHBondContact O-OG 2.78Å
94P89.9Confident93.4Very high127 Ų12731.7 Ų31.783%0.82517%0.171SC*.THydrogen-bonded Turntrans-54.9-31.4175-30.236.5000114.6
95N90.2Very high93.1Very high97 Ų9733.2 Ų33.252%0.51919%0.186SC..THydrogen-bonded Turntrans-117.457.9176-169.634.2000110.9N93N93-N95 PolarHBondContact O-N 2.77Å; N93-N95 VanDerWaalsContact O-N 3.13Å; N93-N95 PolarHBondContact OD1-N 2.76Å; N93-N95 VanDerWaalsContact OD1-N 3.12Å
96S94.1Very high93.1Very high3 Ų333 Ų332%0.02118%0.184CC..  trans-60.6146.1-179.5-61.30000113.2E90 L91 N93 H98 I99E90-S96 WeakPolarHBondContact O-CB 3.37Å; E90-S96 PolarHBondContact O-OG 3.41Å; L91-S96 VanDerWaalsContact C-OG 3.24Å; L91-S96 PolarHBondContact O-OG 3.28Å; N93-S96 PolarHBondContact N-OG 2.79Å; N93-S96 PolarHBondContact O-N 3.14Å; N93-S96 PolarHBondContact O-OG 2.78Å; S96-H98 VanDerWaalsContact C-N 3.29Å; S96-H98 WeakPolarHBondContact CB-CE1 3.3Å; S96-H98 VanDerWaalsContact CB-ND1 3.3Å; S96-H98 WeakPolarHBondContact CB-ND1 3.29Å; S96-H98 PolarHBondContact O-N 2.74Å; S96-I99 WeakPolarHBondContact O-CB 3.44Å; S96-I99 PolarHBondContact O-N 2.71Å; S96-I99 VanDerWaalsContact O-N 3.15Å
97P94.2Very high93.1Very high12 Ų1234.5 Ų34.58%0.07819%0.192CC..Hα-helixtrans-54.6-37.4179.8-28.636.3000115E86 E90 I99 Q100 M101E86-P97 HydrophobicContact CG-CB 4.41Å; E86-P97 HydrophobicContact CG-CG 4.22Å; E86-P97 WeakPolarHBondContact OE2-CD 3.3Å; E90-P97 HydrophobicContact CB-CG 3.96Å; E90-P97 HydrophobicContact CG-CG 4.23Å; E90-P97 WeakPolarHBondContact O-CD 3.1Å; P97-I99 PolarHBondContact O-N 3.16Å; P97-I99 VanDerWaalsContact O-N 3.16Å; P97-Q100 PolarHBondContact O-N 2.81Å; P97-M101 HydrophobicContact CB-CE 3.82Å; P97-M101 HydrophobicContact CB-SD 4.25Å; P97-M101 WeakPolarHBondContact O-CB 3.13Å; P97-M101 VanDerWaalsContact O-CG 3.29Å; P97-M101 WeakPolarHBondContact O-CG 3.4Å; P97-M101 PolarHBondContact O-N 2.99Å
98H94.4Very high93.2Very high13 Ų1335.1 Ų35.16%0.0620%0.195CC..Hα-helixtrans-58.1-28.918067.4-97.1000113.6E86 S96 M101 G102 F109E86-H98 IonicContact OE1-ND1 2.87Å; E86-H98 IonicContact OE2-CG 3.65Å; E86-H98 PolarHBondContact OE2-N 3.21Å; E86-H98 IonicContact OE2-ND1 3.82Å; E86-H98 PolarHBondContact OE2-ND1 3.08Å; S96-H98 VanDerWaalsContact C-N 3.29Å; S96-H98 WeakPolarHBondContact CB-CE1 3.3Å; S96-H98 VanDerWaalsContact CB-ND1 3.3Å; S96-H98 WeakPolarHBondContact CB-ND1 3.29Å; S96-H98 PolarHBondContact O-N 2.74Å; H98-M101 PolarHBondContact O-N 2.8Å; H98-G102 PolarHBondContact O-N 2.92Å; H98-F109 HydrophobicContact CB-CD1 4.01Å; H98-F109 HydrophobicContact CB-CE1 4.12Å; H98-F109 HydrophobicContact CB-CG 4.34Å
99I92.7Very high93.3Very high32 Ų3235 Ų3516%0.16419%0.193CC..Hα-helixtrans-60.9-53.7179.5-59.5173000109.5S96 P97 G102 L103S96-I99 WeakPolarHBondContact O-CB 3.44Å; S96-I99 PolarHBondContact O-N 2.71Å; S96-I99 VanDerWaalsContact O-N 3.15Å; P97-I99 PolarHBondContact O-N 3.16Å; P97-I99 VanDerWaalsContact O-N 3.16Å; I99-G102 PolarHBondContact O-N 2.78Å; I99-L103 WeakPolarHBondContact O-CG 3.38Å; I99-L103 PolarHBondContact O-N 3Å; I99-L103 VanDerWaalsContact O-N 3.15Å
100Q90.3Very high93.5Very high37 Ų3736 Ų3617%0.17320%0.199CC..Hα-helixtrans-76.1-30.8-177.5-61.4-62.7-25.100111.9P97 D104 Q207P97-Q100 PolarHBondContact O-N 2.81Å; Q100-D104 WeakPolarHBondContact O-CB 3.45Å; Q100-D104 PolarHBondContact O-N 2.93Å; Q100-D104 VanDerWaalsContact O-N 3.08Å; Q100-Q207 VanDerWaalsContact CD-OE1 3.3Å; Q100-Q207 VanDerWaalsContact OE1-OE1 3.12Å
101M93.1Very high93.6Very high0 Ų036.2 Ų36.20%020%0.2CC..Hα-helixtrans-64.5-42.7171.8-71.3173.7-176.600111.4V75 T85 P97 H98 D104 G105 V106 F109V75-M101 HydrophobicContact CG1-CG 4.37Å; T85-M101 WeakPolarHBondContact O-CE 3.21Å; P97-M101 HydrophobicContact CB-CE 3.82Å; P97-M101 HydrophobicContact CB-SD 4.25Å; P97-M101 WeakPolarHBondContact O-CB 3.13Å; P97-M101 VanDerWaalsContact O-CG 3.29Å; P97-M101 WeakPolarHBondContact O-CG 3.4Å; P97-M101 PolarHBondContact O-N 2.99Å; H98-M101 PolarHBondContact O-N 2.8Å; M101-D104 CarbonylContact O-C 3.58Å; M101-D104 PolarHBondContact O-N 2.81Å; M101-G105 PolarHBondContact O-N 3.17Å; M101-V106 HydrophobicContact CB-CB 3.88Å; M101-V106 HydrophobicContact CB-CG1 4.33Å; M101-V106 HydrophobicContact CB-CG2 3.8Å; M101-V106 HydrophobicContact CG-CG2 4.35Å; M101-V106 WeakPolarHBondContact O-CB 3.21Å; M101-V106 VanDerWaalsContact O-CG2 3.3Å; M101-V106 WeakPolarHBondContact O-CG2 3.22Å; M101-V106 PolarHBondContact O-N 2.77Å; M101-F109 HydrophobicContact CB-CD1 4.19Å; M101-F109 HydrophobicContact CB-CE1 3.64Å; M101-F109 HydrophobicContact SD-CD1 4.36Å
102G91.9Very high93.6Very high10 Ų1036.9 Ų36.910%0.10321%0.205CC..Hα-helixtrans-62.6-42.9176.600000112.6H98 I99 D104 G105H98-G102 PolarHBondContact O-N 2.92Å; I99-G102 PolarHBondContact O-N 2.78Å; G102-D104 VanDerWaalsContact C-N 3.28Å; G102-D104 PolarHBondContact O-N 3.15Å; G102-G105 PolarHBondContact O-N 2.56Å
103L89.5Confident93.9Very high82 Ų8232 Ų3243%0.42919%0.189SC..Hα-helixtrans-60.7-36172.8-72.4175.5000112.8I99 G105I99-L103 WeakPolarHBondContact O-CG 3.38Å; I99-L103 PolarHBondContact O-N 3Å; I99-L103 VanDerWaalsContact O-N 3.15Å; L103-G105 PolarHBondContact O-N 3.21Å
104D89.8Confident94.2Very high46 Ų4631 Ų3125%0.24619%0.188CC..THydrogen-bonded Turntrans-78.55.4175.1-86.1-4000113.4R49 Q100 M101 G102 C210 R212R49-D104 IonicContact NH2-OD2 3.98Å; Q100-D104 WeakPolarHBondContact O-CB 3.45Å; Q100-D104 PolarHBondContact O-N 2.93Å; Q100-D104 VanDerWaalsContact O-N 3.08Å; M101-D104 CarbonylContact O-C 3.58Å; M101-D104 PolarHBondContact O-N 2.81Å; G102-D104 VanDerWaalsContact C-N 3.28Å; G102-D104 PolarHBondContact O-N 3.15Å; D104-C210 VanDerWaalsContact OD2-CB 3.24Å; D104-C210 WeakPolarHBondContact OD2-CB 3.36Å; D104-C210 PolarHBondContact OD2-N 3.49Å; D104-C210 PolarHBondContact OD2-SG 3.12Å; D104-R212 PolarHBondContact O-NH2 2.85Å
105G91.6Very high94.5Very high31 Ų3125.2 Ų25.232%0.3215%0.151SC..THydrogen-bonded Turntrans81.418.7176.700000114.9S82 M101 G102 L103 E107S82-G105 PolarHBondContact OG-O 3.45Å; S82-G105 VanDerWaalsContact OG-O 3.09Å; M101-G105 PolarHBondContact O-N 3.17Å; G102-G105 PolarHBondContact O-N 2.56Å; L103-G105 PolarHBondContact O-N 3.21Å; G105-E107 PolarHBondContact O-N 3.11Å
106V95.8Very high94.9Very high0 Ų020.9 Ų20.90%013%0.128CC..  trans-66.8128.1171.3176.90000109.9V75 S82 G84 M101 I108 F109 R195V75-V106 HydrophobicContact CB-CG2 4.25Å; V75-V106 HydrophobicContact CG1-CG2 3.84Å; V75-V106 HydrophobicContact CG2-CG2 4.38Å; S82-V106 WeakPolarHBondContact OG-CA 3.36Å; G84-V106 VanDerWaalsContact N-CG1 3.31Å; M101-V106 HydrophobicContact CB-CB 3.88Å; M101-V106 HydrophobicContact CB-CG1 4.33Å; M101-V106 HydrophobicContact CB-CG2 3.8Å; M101-V106 HydrophobicContact CG-CG2 4.35Å; M101-V106 WeakPolarHBondContact O-CB 3.21Å; M101-V106 VanDerWaalsContact O-CG2 3.3Å; M101-V106 WeakPolarHBondContact O-CG2 3.22Å; M101-V106 PolarHBondContact O-N 2.77Å; V106-I108 WeakPolarHBondContact CG1-O 3.46Å; V106-F109 HydrophobicContact CB-CE1 3.97Å; V106-F109 HydrophobicContact CG1-CD1 3.95Å; V106-F109 HydrophobicContact CG1-CE1 3.74Å; V106-R195 VanDerWaalsContact O-CZ 3.28Å; V106-R195 PolarHBondContact O-NH1 3.5Å; V106-R195 PolarHBondContact O-NH2 3.01Å
107E97.4Very high95.1Very high34 Ų3420.8 Ų20.816%0.15913%0.127CC..  trans-98.8-30.9-176.3-70.4158.1168.600112.1T81 S82 G105 G138 I139 V191T81-E107 WeakPolarHBondContact CA-OE2 3.33Å; T81-E107 VanDerWaalsContact CB-OE2 3.28Å; T81-E107 WeakPolarHBondContact CB-OE2 3.29Å; T81-E107 PolarHBondContact OG1-OE2 3.03Å; S82-E107 PolarHBondContact O-N 3.25Å; G105-E107 PolarHBondContact O-N 3.11Å; E107-G138 CarbonylContact O-C 3.56Å; E107-G138 VanDerWaalsContact O-CA 3.28Å; E107-G138 WeakPolarHBondContact O-CA 3.28Å; E107-I139 PolarHBondContact O-N 3.39Å; E107-V191 HydrophobicContact CB-CG1 4.31Å; E107-V191 HydrophobicContact CG-CG1 4.08Å
108I98.4Very high95.3Very high17 Ų1722 Ų229%0.08713%0.132CC..EExtended strand (participates in β ladder)trans-117.8122.5-177.9-53.8-178.4000110.3T81 S82 I83 G84 V106 T110 I139 L141 L188 L219T81-I108 HydrophobicContact CG2-CD1 4.04Å; S82-I108 PolarHBondContact O-N 2.99Å; S82-I108 VanDerWaalsContact O-N 3.15Å; I83-I108 CarbonylContact C-O 3.58Å; I83-I108 WeakPolarHBondContact CA-O 3.47Å; I83-I108 HydrophobicContact CG1-CB 4.25Å; I83-I108 HydrophobicContact CG1-CD1 4.4Å; I83-I108 HydrophobicContact CG2-CB 4.36Å; I83-I108 HydrophobicContact CG2-CG2 4.29Å; G84-I108 PolarHBondContact N-O 3.03Å; V106-I108 WeakPolarHBondContact CG1-O 3.46Å; I108-T110 HydrophobicContact CG2-CG2 4.5Å; I108-I139 CarbonylContact C-O 3.13Å; I108-I139 WeakPolarHBondContact CA-O 3.3Å; I108-I139 HydrophobicContact CG1-CB 4.37Å; I108-I139 HydrophobicContact CG1-CD1 4.34Å; I108-L141 HydrophobicContact CG2-CD1 3.35Å; I108-L188 HydrophobicContact CD1-CD2 4.28Å; I108-L188 HydrophobicContact CG1-CD2 4.39Å; I108-L219 HydrophobicContact CD1-CD2 3.97Å
109F98.1Very high95.5Very high3 Ų321.9 Ų21.91%0.01313%0.131CC..EExtended strand (participates in β ladder)trans-106.4130.2172.9-47.3-74.5000109.9H98 M101 V106 I139 Y140 L141H98-F109 HydrophobicContact CB-CD1 4.01Å; H98-F109 HydrophobicContact CB-CE1 4.12Å; H98-F109 HydrophobicContact CB-CG 4.34Å; M101-F109 HydrophobicContact CB-CD1 4.19Å; M101-F109 HydrophobicContact CB-CE1 3.64Å; M101-F109 HydrophobicContact SD-CD1 4.36Å; V106-F109 HydrophobicContact CB-CE1 3.97Å; V106-F109 HydrophobicContact CG1-CD1 3.95Å; V106-F109 HydrophobicContact CG1-CE1 3.74Å; F109-I139 WeakPolarHBondContact CD2-O 3.47Å; F109-I139 PolarHBondContact N-O 3.02Å; F109-Y140 HydrophobicContact CB-CD2 3.62Å; F109-Y140 HydrophobicContact CB-CE2 3.94Å; F109-Y140 HydrophobicContact CB-CG 4.23Å; F109-Y140 HydrophobicContact CD2-CD2 4.04Å; F109-Y140 HydrophobicContact CG-CD2 4.14Å; F109-Y140 WeakPolarHBondContact O-CA 3.23Å; F109-L141 PolarHBondContact O-N 3.33Å
110T98.3Very high95.7Very high32 Ų3224.8 Ų24.820%0.19614%0.14CC..EExtended strand (participates in β ladder)trans-111.3124.8174.9560000109.9I83 G84 T85 E86 I108 L141I83-T110 HydrophobicContact CG2-CG2 4.07Å; G84-T110 PolarHBondContact O-N 2.93Å; G84-T110 PolarHBondContact O-OG1 3.45Å; T85-T110 WeakPolarHBondContact CA-O 3.44Å; T85-T110 PolarHBondContact OG1-OG1 3Å; E86-T110 PolarHBondContact N-O 3.05Å; I108-T110 HydrophobicContact CG2-CG2 4.5Å; T110-L141 HydrophobicContact CG2-CB 4.45Å; T110-L141 HydrophobicContact CG2-CD1 4.45Å
111N98.4Very high96Very high3 Ų324.3 Ų24.32%0.01614%0.137CC..EExtended strand (participates in β ladder)trans-120.2115.4174.6-170.8-45.2000111.1E86 C88 S113 Y140 L141 Y142 A143E86-N111 HydrophobicContact CB-CB 4.44Å; E86-N111 VanDerWaalsContact O-CA 3.3Å; E86-N111 WeakPolarHBondContact O-CA 3.46Å; C88-N111 WeakPolarHBondContact CA-OD1 3.44Å; C88-N111 PolarHBondContact N-OD1 3.02Å; C88-N111 PolarHBondContact O-ND2 2.74Å; N111-S113 PolarHBondContact OD1-OG 3.24Å; N111-Y140 HydrophobicContact CB-CE1 3.51Å; N111-Y140 VanDerWaalsContact CB-OH 3.22Å; N111-Y140 WeakPolarHBondContact CB-OH 3.49Å; N111-Y140 PolarHBondContact ND2-OH 2.93Å; N111-L141 PolarHBondContact N-O 2.54Å; N111-Y142 HydrophobicContact CB-CD2 4.18Å; N111-Y142 WeakPolarHBondContact O-CA 3.07Å; N111-A143 PolarHBondContact O-N 2.83Å
112S97.1Very high96.1Very high21 Ų2124.4 Ų24.415%0.14714%0.138CC..EExtended strand (participates in β ladder)trans-100.4128.1167.767.10000111R13 C88 A143R13-S112 WeakPolarHBondContact CD-OG 3.34Å; R13-S112 PolarHBondContact NE-OG 3.16Å; R13-S112 PolarHBondContact NH1-OG 3.15Å; R13-S112 VanDerWaalsContact NH1-OG 3.14Å; C88-S112 PolarHBondContact N-O 2.93Å; C88-S112 VanDerWaalsContact N-O 3.16Å; S112-A143 CarbonylContact C-O 3.49Å; S112-A143 WeakPolarHBondContact CA-O 3.28Å
113S97.3Very high96.3Very high14 Ų1427 Ų2710%0.09815%0.15CC..EExtended strand (participates in β ladder)trans-122.6158.5-173.6-76.10000112.6C88 N111 Y142 A143 N144 Q145C88-S113 WeakPolarHBondContact CA-OG 3.36Å; N111-S113 PolarHBondContact OD1-OG 3.24Å; S113-Y142 WeakPolarHBondContact CB-OH 3.5Å; S113-Y142 WeakPolarHBondContact OG-CE2 3.47Å; S113-Y142 PolarHBondContact OG-OH 2.97Å; S113-A143 PolarHBondContact N-O 3.2Å; S113-N144 WeakPolarHBondContact O-CA 3.29Å; S113-N144 PolarHBondContact O-OD1 3.23Å; S113-N144 VanDerWaalsContact O-OD1 3.06Å; S113-Q145 PolarHBondContact O-N 2.7Å
114A96.6Very high96.6Very high36 Ų3628.3 Ų28.330%0.29815%0.154SC..  trans-131.966.1162.500000106Y36 N144 Y155Y36-A114 WeakPolarHBondContact CE1-O 3.31Å; Y36-A114 PolarHBondContact OH-O 3.45Å; A114-N144 VanDerWaalsContact CA-OD1 3.25Å; A114-N144 WeakPolarHBondContact CA-OD1 3.3Å; A114-N144 PolarHBondContact N-OD1 2.82Å; A114-Y155 HydrophobicContact CB-CD1 4.22Å; A114-Y155 HydrophobicContact CB-CE1 3.79Å; A114-Y155 VanDerWaalsContact O-CE1 3.31Å; A114-Y155 WeakPolarHBondContact O-CE1 3.4Å
115S96.6Very high96.9Very high7 Ų726.8 Ų26.85%0.04915%0.145CC..  trans-92.4113-179.5-1790000109.9Y36 R125 N144Y36-S115 WeakPolarHBondContact OH-CA 3.14Å; S115-R125 PolarHBondContact OG-NH2 3.37Å; S115-N144 PolarHBondContact N-OD1 2.68Å; S115-N144 PolarHBondContact O-ND2 3.39Å
116H97.9Very high97.2Very high5 Ų525.5 Ų25.52%0.02313%0.131CC..BIsolated β-bridgetrans-70.9156.217664.7-82.1000112.4Y36 K121 L153 Y154 Y155 H570Y36-H116 AromaticContact CE1-ND1 3.87Å; Y36-H116 AromaticContact CE2-CE1 3.46Å; Y36-H116 VanDerWaalsContact CE2-CE1 3.46Å; Y36-H116 WeakPolarHBondContact CE2-CE1 3.24Å; Y36-H116 AromaticContact CE2-ND1 3.63Å; Y36-H116 AromaticContact CZ-CE1 3.54Å; Y36-H116 AromaticContact CZ-ND1 3.17Å; Y36-H116 PolarHBondContact OH-CE1 2.98Å; Y36-H116 PolarHBondContact OH-N 3.07Å; Y36-H116 PolarHBondContact OH-ND1 2.8Å; H116-K121 WeakPolarHBondContact O-CE 3.25Å; H116-K121 PolarHBondContact O-NZ 2.71Å; H116-L153 HydrophobicContact CB-CB 4.02Å; H116-L153 HydrophobicContact CB-CD1 4.03Å; H116-L153 HydrophobicContact CB-CD2 4.2Å; H116-L153 HydrophobicContact CB-CG 4.32Å; H116-Y154 CarbonylContact C-O 3.6Å; H116-Y154 WeakPolarHBondContact CA-O 3.48Å; H116-Y155 HydrophobicContact CB-CD1 4.37Å; H116-Y155 HydrophobicContact CB-CE1 4.41Å; H116-H570 AromaticContact CD2-CD2 3.49Å; H116-H570 PolarHBondContact CD2-CD2 3.49Å; H116-H570 VanDerWaalsContact CD2-CD2 3.49Å; H116-H570 AromaticContact NE2-CD2 3.63Å; H116-H570 AromaticContact NE2-NE2 3.7Å
117H98.5Very high97.2Very high1 Ų129.4 Ų29.41%0.00515%0.151CC..  trans-57.9136.8169.9-176.7-124.8000110.3Y154 D156 F174 E243 Y569H117-Y154 HydrophobicContact CB-CD1 4.4Å; H117-Y154 WeakPolarHBondContact CB-O 3.07Å; H117-Y154 PolarHBondContact N-O 3.16Å; H117-D156 HydrophobicContact CB-CB 3.97Å; H117-D156 IonicContact CD2-OD2 3.3Å; H117-F174 AromaticContact CD2-CZ 3.77Å; H117-F174 AromaticContact NE2-CZ 3.72Å; H117-E243 IonicContact CD2-OE2 3.32Å; H117-E243 IonicContact CE1-OE2 3.35Å; H117-E243 IonicContact NE2-OE2 2.83Å; H117-E243 PolarHBondContact NE2-OE2 3.35Å; H117-Y569 VanDerWaalsContact CG-OH 3.29Å; H117-Y569 AromaticContact ND1-CE1 3.53Å; H117-Y569 AromaticContact ND1-CZ 3.49Å; H117-Y569 PolarHBondContact ND1-OH 3.15Å
118E97.9Very high97.2Very high39 Ų3931 Ų3118%0.18216%0.161CC..  trans-139.8132.7162177.5-175.1131.100104.6R120 K121 A571 S573E118-R120 PolarHBondContact O-N 2.9Å; E118-K121 HydrophobicContact CB-CB 3.8Å; E118-K121 HydrophobicContact CB-CD 3.76Å; E118-K121 HydrophobicContact CB-CG 4.4Å; E118-K121 VanDerWaalsContact CB-NZ 3.28Å; E118-K121 HydrophobicContact CG-CB 4.26Å; E118-K121 HydrophobicContact CG-CD 4.33Å; E118-K121 VanDerWaalsContact O-CB 3.25Å; E118-K121 WeakPolarHBondContact O-CB 3.42Å; E118-K121 PolarHBondContact O-N 3.12Å; E118-K121 IonicContact OE2-NZ 2.74Å; E118-A571 CarbonylContact C-O 3.52Å; E118-A571 WeakPolarHBondContact CA-O 3.47Å; E118-A571 WeakPolarHBondContact CG-O 3.16Å; E118-S573 VanDerWaalsContact OE1-CB 3.23Å; E118-S573 WeakPolarHBondContact OE1-CB 3.41Å
119L97.9Very high97.2Very high9 Ų930.2 Ų30.25%0.04716%0.157CC..THydrogen-bonded Turntrans-57122.8-172.2-172.661000109.3E243 I244 A571L119-E243 WeakPolarHBondContact CA-OE2 3.48Å; L119-E243 HydrophobicContact CD1-CB 3.67Å; L119-E243 WeakPolarHBondContact CD1-OE2 3.38Å; L119-I244 HydrophobicContact CD1-CD1 4.47Å; L119-I244 HydrophobicContact CD1-CG1 3.96Å; L119-I244 HydrophobicContact CD2-CD1 4.16Å; L119-I244 HydrophobicContact CD2-CG1 4.28Å; L119-A571 HydrophobicContact CB-CB 4.24Å; L119-A571 PolarHBondContact N-O 3.34Å
120R97.3Very high97.1Very high93 Ų9333.1 Ų33.135%0.35117%0.169SC..THydrogen-bonded Turntrans70.118.7-177.7-49148.5176.31141.9115.9E118 P240 E243 D458 E572E118-R120 PolarHBondContact O-N 2.9Å; R120-P240 HydrophobicContact CG-CB 4.48Å; R120-P240 HydrophobicContact CG-CG 4.09Å; R120-E243 PolarHBondContact N-OE2 3.48Å; R120-D458 IonicContact CZ-OD1 2.87Å; R120-D458 IonicContact CZ-OD2 3.71Å; R120-D458 IonicContact NH1-OD1 2.86Å; R120-D458 IonicContact NH1-OD2 3.88Å; R120-D458 PolarHBondContact NH1-OD2 3.39Å; R120-D458 IonicContact NH2-OD1 2.73Å; R120-D458 PolarHBondContact NH2-OD1 2.93Å; R120-D458 IonicContact NH2-OD2 2.67Å; R120-D458 PolarHBondContact NH2-OD2 3.35Å; R120-D458 VanDerWaalsContact NH2-OD2 3.09Å; R120-E572 IonicContact NH1-OE1 3.02Å
121K96.4Very high97Very high27 Ų2735.9 Ų35.912%0.11719%0.186CC..  trans-90.5-15.2179-174.8179.765.7-161.10114.2H116 E118 D123 Q124 R125H116-K121 WeakPolarHBondContact O-CE 3.25Å; H116-K121 PolarHBondContact O-NZ 2.71Å; E118-K121 HydrophobicContact CB-CB 3.8Å; E118-K121 HydrophobicContact CB-CD 3.76Å; E118-K121 HydrophobicContact CB-CG 4.4Å; E118-K121 VanDerWaalsContact CB-NZ 3.28Å; E118-K121 HydrophobicContact CG-CB 4.26Å; E118-K121 HydrophobicContact CG-CD 4.33Å; E118-K121 VanDerWaalsContact O-CB 3.25Å; E118-K121 WeakPolarHBondContact O-CB 3.42Å; E118-K121 PolarHBondContact O-N 3.12Å; E118-K121 IonicContact OE2-NZ 2.74Å; K121-D123 PolarHBondContact O-N 3.27Å; K121-Q124 PolarHBondContact O-N 3.13Å; K121-R125 PolarHBondContact O-N 3.15Å
122A95.9Very high96.8Very high2 Ų236 Ų362%0.01719%0.187CC..Hα-helixtrans-59.2-36.2-172.300000113Q124 R125 V126 F237A122-Q124 PolarHBondContact O-N 3.47Å; A122-R125 WeakPolarHBondContact O-CB 3.33Å; A122-R125 PolarHBondContact O-N 3.1Å; A122-V126 WeakPolarHBondContact O-CG2 3.46Å; A122-V126 PolarHBondContact O-N 3.06Å; A122-V126 VanDerWaalsContact O-N 3.13Å; A122-F237 HydrophobicContact CB-CD1 4.25Å; A122-F237 HydrophobicContact CB-CE1 4.36Å
123D95.9Very high96.7Very high64 Ų6435 Ų3534%0.34218%0.18SC..Hα-helixtrans-60.2-43.9177.670.6-32.3000112.9K121 R125 V126 N127 F237K121-D123 PolarHBondContact O-N 3.27Å; D123-R125 VanDerWaalsContact C-N 3.28Å; D123-R125 PolarHBondContact O-N 3.02Å; D123-V126 PolarHBondContact O-N 2.76Å; D123-N127 VanDerWaalsContact O-CB 3.32Å; D123-N127 WeakPolarHBondContact O-CB 3.43Å; D123-N127 PolarHBondContact O-N 2.87Å; D123-N127 PolarHBondContact O-ND2 3.43Å; D123-N127 VanDerWaalsContact O-ND2 3.17Å; D123-F237 HydrophobicContact CB-CD1 4.3Å; D123-F237 HydrophobicContact CB-CE1 3.85Å; D123-F237 HydrophobicContact CB-CE2 4.47Å; D123-F237 HydrophobicContact CB-CZ 3.95Å
124Q95.7Very high96.6Very high110 Ų11037.5 Ų37.551%0.51420%0.195SC..Hα-helixtrans-59.8-41.8178.4-65.7173.92800110.7K121 A122 N127 L128K121-Q124 PolarHBondContact O-N 3.13Å; A122-Q124 PolarHBondContact O-N 3.47Å; Q124-N127 PolarHBondContact O-N 3.22Å; Q124-L128 WeakPolarHBondContact O-CB 3.28Å; Q124-L128 VanDerWaalsContact O-CG 3.24Å; Q124-L128 WeakPolarHBondContact O-CG 3.49Å; Q124-L128 PolarHBondContact O-N 2.61Å
125R96.3Very high96.3Very high15 Ų1541.9 Ų41.96%0.05721%0.207CC..Hα-helixtrans-64.1-49.6178.3-175.7-169.9-56.7172.213.1111.6S115 K121 A122 D123 N127 L128 I129 Y142 N144 D156 G157S115-R125 PolarHBondContact OG-NH2 3.37Å; K121-R125 PolarHBondContact O-N 3.15Å; A122-R125 WeakPolarHBondContact O-CB 3.33Å; A122-R125 PolarHBondContact O-N 3.1Å; D123-R125 VanDerWaalsContact C-N 3.28Å; D123-R125 PolarHBondContact O-N 3.02Å; R125-N127 VanDerWaalsContact C-N 3.31Å; R125-N127 PolarHBondContact O-N 3.01Å; R125-L128 PolarHBondContact O-N 3.29Å; R125-I129 HydrophobicContact CG-CD1 4.3Å; R125-I129 PolarHBondContact O-N 2.82Å; R125-Y142 WeakPolarHBondContact CD-OH 3.43Å; R125-N144 PolarHBondContact NH1-ND2 3.01Å; R125-D156 IonicContact CZ-OD1 3.88Å; R125-D156 IonicContact CZ-OD2 3.65Å; R125-D156 IonicContact NH1-OD1 2.7Å; R125-D156 PolarHBondContact NH1-OD1 3.15Å; R125-D156 IonicContact NH1-OD2 3.62Å; R125-D156 VanDerWaalsContact NH2-CG 3.33Å; R125-D156 IonicContact NH2-OD1 4Å; R125-D156 PolarHBondContact NH2-OD1 3.37Å; R125-D156 IonicContact NH2-OD2 3.74Å; R125-D156 PolarHBondContact NH2-OD2 3.35Å; R125-D156 VanDerWaalsContact NH2-OD2 3.12Å; R125-G157 PolarHBondContact NH1-O 2.86Å
126V97.1Very high96Very high4 Ų442.2 Ų42.22%0.02421%0.21CC..Hα-helixtrans-58.9-46.6177.9174.60000109.9A122 D123 L128 I129 K130 M160 V167 W235 F237A122-V126 WeakPolarHBondContact O-CG2 3.46Å; A122-V126 PolarHBondContact O-N 3.06Å; A122-V126 VanDerWaalsContact O-N 3.13Å; D123-V126 PolarHBondContact O-N 2.76Å; V126-L128 PolarHBondContact O-N 2.88Å; V126-I129 PolarHBondContact O-N 3.26Å; V126-K130 HydrophobicContact CG1-CD 4.04Å; V126-K130 HydrophobicContact CG1-CG 4.27Å; V126-K130 WeakPolarHBondContact O-CG 3.38Å; V126-K130 PolarHBondContact O-N 3.46Å; V126-M160 HydrophobicContact CG2-CE 3.81Å; V126-M160 HydrophobicContact CG2-SD 4.33Å; V126-V167 HydrophobicContact CG1-CG2 4.36Å; V126-W235 HydrophobicContact CG1-CD2 4.26Å; V126-W235 HydrophobicContact CG1-CE3 4.17Å; V126-W235 HydrophobicContact CG1-CG 4.44Å; V126-W235 HydrophobicContact CG2-CD2 3.67Å; V126-W235 HydrophobicContact CG2-CE3 3.82Å; V126-W235 HydrophobicContact CG2-CG 4.3Å; V126-W235 HydrophobicContact CG2-CH2 3.96Å; V126-W235 HydrophobicContact CG2-CZ2 3.79Å; V126-W235 HydrophobicContact CG2-CZ3 3.96Å; V126-F237 HydrophobicContact CB-CE1 4.33Å; V126-F237 HydrophobicContact CB-CZ 4.04Å; V126-F237 HydrophobicContact CG1-CZ 4.24Å; V126-F237 HydrophobicContact CG2-CE1 3.89Å; V126-F237 HydrophobicContact CG2-CZ 4.03Å
127N97.2Very high95.8Very high82 Ų8242 Ų4244%0.43921%0.209SC..Hα-helixtrans-63.8-37.6-179-72.5-27.1000113.4D123 Q124 R125 T131D123-N127 VanDerWaalsContact O-CB 3.32Å; D123-N127 WeakPolarHBondContact O-CB 3.43Å; D123-N127 PolarHBondContact O-N 2.87Å; D123-N127 PolarHBondContact O-ND2 3.43Å; D123-N127 VanDerWaalsContact O-ND2 3.17Å; Q124-N127 PolarHBondContact O-N 3.22Å; R125-N127 VanDerWaalsContact C-N 3.31Å; R125-N127 PolarHBondContact O-N 3.01Å; N127-T131 VanDerWaalsContact O-CB 3.26Å; N127-T131 WeakPolarHBondContact O-CB 3.47Å; N127-T131 PolarHBondContact O-N 3.19Å; N127-T131 PolarHBondContact O-OG1 3.37Å
128L97Very high95.8Very high68 Ų6841.9 Ų41.936%0.35621%0.208SC..Hα-helixtrans-62.1-44174.6-76.2165.6000111.8L91 W92 Q124 R125 V126 T131 A132L91-L128 HydrophobicContact CD2-CB 4.13Å; L91-L128 HydrophobicContact CG-CB 4.32Å; W92-L128 HydrophobicContact CB-CD1 3.87Å; W92-L128 HydrophobicContact CB-CD2 4.21Å; Q124-L128 WeakPolarHBondContact O-CB 3.28Å; Q124-L128 VanDerWaalsContact O-CG 3.24Å; Q124-L128 WeakPolarHBondContact O-CG 3.49Å; Q124-L128 PolarHBondContact O-N 2.61Å; R125-L128 PolarHBondContact O-N 3.29Å; V126-L128 PolarHBondContact O-N 2.88Å; L128-T131 PolarHBondContact O-N 2.89Å; L128-A132 WeakPolarHBondContact O-CB 3.16Å; L128-A132 PolarHBondContact O-N 2.84Å
129I97.2Very high95.8Very high0 Ų040.6 Ų40.60%020%0.202CC..Hα-helixtrans-68.5-44.1179.1-66.3165.6000110.9L91 R125 V126 A132 T133 Y140 Y142 M160 A162L91-I129 HydrophobicContact CD2-CD1 4.48Å; L91-I129 HydrophobicContact CD2-CG1 3.73Å; R125-I129 HydrophobicContact CG-CD1 4.3Å; R125-I129 PolarHBondContact O-N 2.82Å; V126-I129 PolarHBondContact O-N 3.26Å; I129-A132 PolarHBondContact O-N 3.3Å; I129-T133 PolarHBondContact O-N 3.01Å; I129-T133 PolarHBondContact O-OG1 3.18Å; I129-T133 VanDerWaalsContact O-OG1 3.13Å; I129-Y140 HydrophobicContact CG1-CD1 4.3Å; I129-Y140 HydrophobicContact CG1-CE1 4.07Å; I129-Y140 HydrophobicContact CG2-CD1 3.71Å; I129-Y140 HydrophobicContact CG2-CE1 4.33Å; I129-Y140 HydrophobicContact CG2-CG 4Å; I129-Y142 HydrophobicContact CD1-CD1 4.33Å; I129-Y142 HydrophobicContact CD1-CD2 3.7Å; I129-Y142 HydrophobicContact CD1-CE2 4.38Å; I129-Y142 HydrophobicContact CD1-CG 3.67Å; I129-M160 HydrophobicContact CB-SD 4.35Å; I129-M160 HydrophobicContact CD1-CE 3.87Å; I129-M160 HydrophobicContact CD1-CG 4.07Å; I129-M160 HydrophobicContact CD1-SD 3.55Å; I129-M160 VanDerWaalsContact CD1-SD 3.55Å; I129-M160 HydrophobicContact CG2-SD 4.29Å; I129-A162 HydrophobicContact CG2-CB 3.87Å
130K97.3Very high95.8Very high64 Ų6440.1 Ų40.128%0.27820%0.2SC..Hα-helixtrans-57.2-51.3173.7-70.1-172.574171.70110.3V126 A132 T133 T134 G165 E166 V167V126-K130 HydrophobicContact CG1-CD 4.04Å; V126-K130 HydrophobicContact CG1-CG 4.27Å; V126-K130 WeakPolarHBondContact O-CG 3.38Å; V126-K130 PolarHBondContact O-N 3.46Å; K130-A132 VanDerWaalsContact C-N 3.35Å; K130-A132 PolarHBondContact O-N 2.76Å; K130-T133 PolarHBondContact O-N 2.83Å; K130-T133 PolarHBondContact O-OG1 2.89Å; K130-T134 PolarHBondContact O-N 2.74Å; K130-T134 PolarHBondContact O-OG1 2.79Å; K130-G165 WeakPolarHBondContact CE-O 3.19Å; K130-E166 IonicContact NZ-OE2 2.73Å; K130-V167 HydrophobicContact CD-CG2 4.26Å; K130-V167 HydrophobicContact CG-CG2 4.04Å
131T95.8Very high95.9Very high89 Ų8939 Ų3955%0.54620%0.201SC..Hα-helixtrans-63-38.5-178.5-62.90000112.6N127 L128 T133 K135N127-T131 VanDerWaalsContact O-CB 3.26Å; N127-T131 WeakPolarHBondContact O-CB 3.47Å; N127-T131 PolarHBondContact O-N 3.19Å; N127-T131 PolarHBondContact O-OG1 3.37Å; L128-T131 PolarHBondContact O-N 2.89Å; T131-T133 VanDerWaalsContact C-N 3.34Å; T131-T133 PolarHBondContact O-N 2.77Å; T131-K135 VanDerWaalsContact O-CB 3.26Å; T131-K135 WeakPolarHBondContact O-CB 3.04Å; T131-K135 PolarHBondContact O-N 3.39Å
132A94.9Very high96Very high5 Ų538 Ų384%0.04120%0.196CC..Hα-helixtrans-59.2-45.117600000111.6L91 L128 I129 K130 S136L91-A132 HydrophobicContact CD1-CB 4.19Å; L128-A132 WeakPolarHBondContact O-CB 3.16Å; L128-A132 PolarHBondContact O-N 2.84Å; I129-A132 PolarHBondContact O-N 3.3Å; K130-A132 VanDerWaalsContact C-N 3.35Å; K130-A132 PolarHBondContact O-N 2.76Å; A132-S136 WeakPolarHBondContact O-CB 3.22Å; A132-S136 PolarHBondContact O-N 3.23Å; A132-S136 VanDerWaalsContact O-N 3.1Å
133T94.8Very high96.1Very high0 Ų040.5 Ų40.50%022%0.217CC..Hα-helixtrans-79.6-3218053.80000113.7I129 K130 T131 K135 G137 Y140 G165I129-T133 PolarHBondContact O-N 3.01Å; I129-T133 PolarHBondContact O-OG1 3.18Å; I129-T133 VanDerWaalsContact O-OG1 3.13Å; K130-T133 PolarHBondContact O-N 2.83Å; K130-T133 PolarHBondContact O-OG1 2.89Å; T131-T133 VanDerWaalsContact C-N 3.34Å; T131-T133 PolarHBondContact O-N 2.77Å; T133-K135 VanDerWaalsContact C-N 3.34Å; T133-G137 WeakPolarHBondContact O-CA 3.44Å; T133-G137 PolarHBondContact O-N 2.74Å; T133-Y140 HydrophobicContact CG2-CD2 4.32Å; T133-Y140 HydrophobicContact CG2-CG 4.25Å; T133-G165 WeakPolarHBondContact OG1-CA 3.43Å; T133-G165 PolarHBondContact OG1-N 3.48Å
134T95.1Very high96.2Very high67 Ų6738.7 Ų38.741%0.41121%0.207SC..Hα-helixtrans-61.6-43.7170.3-56.40000110.8K130 G165 Y194K130-T134 PolarHBondContact O-N 2.74Å; K130-T134 PolarHBondContact O-OG1 2.79Å; T134-G165 WeakPolarHBondContact OG1-CA 3.28Å; T134-Y194 PolarHBondContact O-OH 3.46Å
135K90.9Very high96.3Very high128 Ų12836.9 Ų36.956%0.55720%0.199SC*.Hα-helixtrans-73.9-44.2-175.8-177.8-179.3175.9-174.30112.7T131 T133T131-K135 VanDerWaalsContact O-CB 3.26Å; T131-K135 WeakPolarHBondContact O-CB 3.04Å; T131-K135 PolarHBondContact O-N 3.39Å; T133-K135 VanDerWaalsContact C-N 3.34Å
136S89.5Confident96.4Very high14 Ų1438.2 Ų38.210%0.09820%0.204CC..Hα-helixtrans-98.2-13.1-172.8-68.60000113.7A132 R195A132-S136 WeakPolarHBondContact O-CB 3.22Å; A132-S136 PolarHBondContact O-N 3.23Å; A132-S136 VanDerWaalsContact O-N 3.1Å; S136-R195 PolarHBondContact O-NE 2.92Å; S136-R195 PolarHBondContact O-NH2 2.96Å
137G94Very high96.5Very high0 Ų038.2 Ų38.20%020%0.204CC..  trans61.8165.2-160.200000111.8T133 N164 R195T133-G137 WeakPolarHBondContact O-CA 3.44Å; T133-G137 PolarHBondContact O-N 2.74Å; G137-N164 WeakPolarHBondContact CA-OD1 3.46Å; G137-R195 PolarHBondContact O-NH2 3.05Å
138G96.9Very high96.5Very high0 Ų034.5 Ų34.50%019%0.185CC..SBendtrans111.6174.8175.700000114.2E107 I163 N164E107-G138 CarbonylContact O-C 3.56Å; E107-G138 VanDerWaalsContact O-CA 3.28Å; E107-G138 WeakPolarHBondContact O-CA 3.28Å; G138-I163 WeakPolarHBondContact O-CA 3.48Å; G138-N164 PolarHBondContact N-OD1 3.22Å; G138-N164 PolarHBondContact O-N 2.9Å; G138-N164 VanDerWaalsContact O-N 3.07Å
139I98.6Very high96.5Very high11 Ų1134.8 Ų34.86%0.05619%0.186CC..EExtended strand (participates in β ladder)trans-97.5133.7-179.4-58.1167.8000108.5E107 I108 F109 L141 V161 A162 I163 L186 L188 V191E107-I139 PolarHBondContact O-N 3.39Å; I108-I139 CarbonylContact C-O 3.13Å; I108-I139 WeakPolarHBondContact CA-O 3.3Å; I108-I139 HydrophobicContact CG1-CB 4.37Å; I108-I139 HydrophobicContact CG1-CD1 4.34Å; F109-I139 WeakPolarHBondContact CD2-O 3.47Å; F109-I139 PolarHBondContact N-O 3.02Å; I139-L141 HydrophobicContact CG2-CD1 3.79Å; I139-V161 HydrophobicContact CG2-CG1 4.06Å; I139-A162 CarbonylContact C-O 3.48Å; I139-A162 VanDerWaalsContact CA-O 3.28Å; I139-A162 WeakPolarHBondContact CA-O 3.42Å; I139-I163 HydrophobicContact CD1-CD1 4.42Å; I139-I163 HydrophobicContact CG1-CB 4.29Å; I139-I163 HydrophobicContact CG1-CD1 3.92Å; I139-I163 HydrophobicContact CG1-CG1 3.95Å; I139-L186 HydrophobicContact CD1-CB 4.08Å; I139-L186 HydrophobicContact CD1-CD1 3.95Å; I139-L186 HydrophobicContact CG1-CD1 4Å; I139-L186 HydrophobicContact CG2-CD1 3.76Å; I139-L188 HydrophobicContact CD1-CD2 3.96Å; I139-V191 HydrophobicContact CD1-CG2 4.35Å; I139-V191 HydrophobicContact CG1-CG2 3.92Å
140Y98.6Very high96.5Very high0 Ų038 Ų380%022%0.219CC..EExtended strand (participates in β ladder)trans-124117.2178.2-159.6-72.1000110.1E86 L91 F109 N111 I129 T133 V161 A162E86-Y140 PolarHBondContact OE1-OH 3.09Å; L91-Y140 HydrophobicContact CD1-CE2 4.23Å; F109-Y140 HydrophobicContact CB-CD2 3.62Å; F109-Y140 HydrophobicContact CB-CE2 3.94Å; F109-Y140 HydrophobicContact CB-CG 4.23Å; F109-Y140 HydrophobicContact CD2-CD2 4.04Å; F109-Y140 HydrophobicContact CG-CD2 4.14Å; F109-Y140 WeakPolarHBondContact O-CA 3.23Å; N111-Y140 HydrophobicContact CB-CE1 3.51Å; N111-Y140 VanDerWaalsContact CB-OH 3.22Å; N111-Y140 WeakPolarHBondContact CB-OH 3.49Å; N111-Y140 PolarHBondContact ND2-OH 2.93Å; I129-Y140 HydrophobicContact CG1-CD1 4.3Å; I129-Y140 HydrophobicContact CG1-CE1 4.07Å; I129-Y140 HydrophobicContact CG2-CD1 3.71Å; I129-Y140 HydrophobicContact CG2-CE1 4.33Å; I129-Y140 HydrophobicContact CG2-CG 4Å; T133-Y140 HydrophobicContact CG2-CD2 4.32Å; T133-Y140 HydrophobicContact CG2-CG 4.25Å; Y140-V161 WeakPolarHBondContact O-CA 3.4Å; Y140-A162 PolarHBondContact N-O 2.87Å; Y140-A162 PolarHBondContact O-N 2.85Å
141L98.6Very high96.5Very high69 Ų6937.2 Ų37.236%0.36122%0.219SC..EExtended strand (participates in β ladder)trans-101.1118.6176.2-66.687.1000108.5I108 F109 T110 N111 I139I108-L141 HydrophobicContact CG2-CD1 3.35Å; F109-L141 PolarHBondContact O-N 3.33Å; T110-L141 HydrophobicContact CG2-CB 4.45Å; T110-L141 HydrophobicContact CG2-CD1 4.45Å; N111-L141 PolarHBondContact N-O 2.54Å; I139-L141 HydrophobicContact CG2-CD1 3.79Å
142Y98.6Very high96.6Very high7 Ų733.9 Ų33.93%0.02720%0.196CC..EExtended strand (participates in β ladder)trans-112.2125.1175.9179.7-92.4000109.9N111 S113 R125 I129 N144 C158 A159 M160N111-Y142 HydrophobicContact CB-CD2 4.18Å; N111-Y142 WeakPolarHBondContact O-CA 3.07Å; S113-Y142 WeakPolarHBondContact CB-OH 3.5Å; S113-Y142 WeakPolarHBondContact OG-CE2 3.47Å; S113-Y142 PolarHBondContact OG-OH 2.97Å; R125-Y142 WeakPolarHBondContact CD-OH 3.43Å; I129-Y142 HydrophobicContact CD1-CD1 4.33Å; I129-Y142 HydrophobicContact CD1-CD2 3.7Å; I129-Y142 HydrophobicContact CD1-CE2 4.38Å; I129-Y142 HydrophobicContact CD1-CG 3.67Å; Y142-N144 HydrophobicContact CE1-CB 3.64Å; Y142-C158 VanDerWaalsContact CD1-O 3.28Å; Y142-C158 WeakPolarHBondContact CD1-O 3.16Å; Y142-A159 CarbonylContact O-C 3.31Å; Y142-A159 WeakPolarHBondContact O-CA 3.44Å; Y142-M160 HydrophobicContact CD1-CE 4.35Å; Y142-M160 PolarHBondContact N-O 2.8Å; Y142-M160 PolarHBondContact O-N 3.45Å
143A98.4Very high96.8Very high54 Ų5433.8 Ų33.845%0.44620%0.195SC..EExtended strand (participates in β ladder)trans-123.6139.1173.300000109.3N111 S112 S113N111-A143 PolarHBondContact O-N 2.83Å; S112-A143 CarbonylContact C-O 3.49Å; S112-A143 WeakPolarHBondContact CA-O 3.28Å; S113-A143 PolarHBondContact N-O 3.2Å
144N98.3Very high97Very high26 Ų2633.8 Ų33.814%0.13920%0.195CC..EExtended strand (participates in β ladder)trans-137155.1-179.8-169.629.1000110.2S113 A114 S115 R125 Y142 D156 G157S113-N144 WeakPolarHBondContact O-CA 3.29Å; S113-N144 PolarHBondContact O-OD1 3.23Å; S113-N144 VanDerWaalsContact O-OD1 3.06Å; A114-N144 VanDerWaalsContact CA-OD1 3.25Å; A114-N144 WeakPolarHBondContact CA-OD1 3.3Å; A114-N144 PolarHBondContact N-OD1 2.82Å; S115-N144 PolarHBondContact N-OD1 2.68Å; S115-N144 PolarHBondContact O-ND2 3.39Å; R125-N144 PolarHBondContact NH1-ND2 3.01Å; Y142-N144 HydrophobicContact CE1-CB 3.64Å; N144-D156 PolarHBondContact ND2-OD1 3.28Å; N144-G157 WeakPolarHBondContact CB-O 3.18Å; N144-G157 PolarHBondContact ND2-N 3.46Å; N144-G157 PolarHBondContact ND2-O 3.29Å
145Q98.1Very high97.2Very high71 Ų7131.7 Ų31.733%0.33218%0.179SC..  trans-62.6149.2166.4-169.4167.6-5.300110.2S113 D149 Y155 G157S113-Q145 PolarHBondContact O-N 2.7Å; Q145-D149 PolarHBondContact NE2-OD2 3.22Å; Q145-D149 VanDerWaalsContact NE2-OD2 3.1Å; Q145-Y155 HydrophobicContact CB-CD1 4.15Å; Q145-Y155 HydrophobicContact CB-CG 3.98Å; Q145-Y155 HydrophobicContact CG-CD2 4.22Å; Q145-Y155 HydrophobicContact CG-CG 4.02Å; Q145-Y155 WeakPolarHBondContact O-CB 3.17Å; Q145-G157 WeakPolarHBondContact O-CA 3.34Å; Q145-G157 PolarHBondContact O-N 2.71Å
146R98.1Very high97.5Very high44 Ų4425.6 Ų25.617%0.16615%0.153CC..EExtended strand (participates in β ladder)trans-132.5138.5172.7-167.2175.167-171.97109.9Y155 S175 D177 E180R146-Y155 CarbonylContact C-O 3.57Å; R146-Y155 WeakPolarHBondContact CA-O 3.21Å; R146-S175 VanDerWaalsContact CZ-CB 3.46Å; R146-S175 PolarHBondContact NH2-OG 2.79Å; R146-S175 VanDerWaalsContact NH2-OG 3.12Å; R146-D177 VanDerWaalsContact NH2-CB 3.34Å; R146-D177 PolarHBondContact NH2-O 3.41Å; R146-D177 IonicContact NH2-OD2 2.97Å; R146-E180 IonicContact CZ-OE2 2.84Å; R146-E180 IonicContact NH1-OE1 3.36Å; R146-E180 PolarHBondContact NH1-OE1 3.1Å; R146-E180 IonicContact NH1-OE2 3.66Å; R146-E180 PolarHBondContact NH1-OE2 3.48Å
147G98.3Very high97.8Very high3 Ų325 Ų253%0.03115%0.15CC..EExtended strand (participates in β ladder)trans104.2177.6-176.900000113.9Y154 Y155 D254G147-Y154 VanDerWaalsContact CA-CE2 3.4Å; G147-Y155 PolarHBondContact N-O 3.41Å; G147-Y155 WeakPolarHBondContact O-CD2 3.49Å; G147-Y155 PolarHBondContact O-N 2.92Å; G147-D254 WeakPolarHBondContact CA-OD2 3.4Å
148C98.3Very high97.9Very high5 Ų525.1 Ų25.13%0.03415%0.15CC..  trans-79.5146.3164.8176.50000109.1D151 D254 Y255 R258C148-D151 PolarHBondContact SG-O 2.85Å; C148-D254 HydrophobicContact CB-CB 3.67Å; C148-D254 PolarHBondContact N-OD2 3.49Å; C148-Y255 WeakPolarHBondContact SG-CE2 3.38Å; C148-R258 PolarHBondContact O-NH1 3.38Å; C148-R258 PolarHBondContact O-NH2 3.03Å
149D97.4Very high98Very high73 Ų7326 Ų2639%0.3916%0.158SC..  trans-121.510.1178.475.9-15.4000114.8Q145 Y155Q145-D149 PolarHBondContact NE2-OD2 3.22Å; Q145-D149 VanDerWaalsContact NE2-OD2 3.1Å; D149-Y155 HydrophobicContact CB-CE2 4.33Å; D149-Y155 WeakPolarHBondContact OD1-CE2 3.42Å; D149-Y155 WeakPolarHBondContact OD2-CE2 3.1Å
150G96.9Very high97.9Very high67 Ų6725.6 Ų25.669%0.69116%0.156SC*.SBendtrans127.87.6174.900000114.6
151D97.4Very high97.9Very high49 Ų4926.2 Ų26.226%0.26216%0.159SC..SBendtrans-137.4-158.3175.284.5-2.1000113C148 L153 W251 Y255C148-D151 PolarHBondContact SG-O 2.85Å; D151-L153 VanDerWaalsContact C-N 3.28Å; D151-L153 PolarHBondContact O-N 2.85Å; D151-L153 VanDerWaalsContact OD1-CB 3.3Å; D151-L153 WeakPolarHBondContact OD1-CB 3.43Å; D151-L153 WeakPolarHBondContact OD1-CG 3.49Å; D151-L153 PolarHBondContact OD1-N 3.46Å; D151-W251 PolarHBondContact O-NE1 3Å; D151-Y255 WeakPolarHBondContact O-CE2 3.42Å; D151-Y255 PolarHBondContact O-OH 3.12Å
152R97.8Very high97.9Very high18 Ų1822.9 Ų22.97%0.06814%0.142CC..SBendtrans-80-7.2-175.769.1174.961.4-150.17.7114.9S568 H570 D577 N579R152-S568 WeakPolarHBondContact CB-O 3.05Å; R152-H570 PolarHBondContact O-N 3.43Å; R152-D577 VanDerWaalsContact CZ-CG 3.43Å; R152-D577 IonicContact CZ-OD1 2.71Å; R152-D577 IonicContact CZ-OD2 2.74Å; R152-D577 IonicContact NH1-OD1 3.58Å; R152-D577 PolarHBondContact NH1-OD1 3.44Å; R152-D577 IonicContact NH1-OD2 3.59Å; R152-D577 PolarHBondContact NH1-OD2 2.84Å; R152-D577 IonicContact NH2-OD2 2.93Å; R152-D577 PolarHBondContact NH2-OD2 3.46Å; R152-D577 VanDerWaalsContact NH2-OD2 3.09Å; R152-N579 PolarHBondContact NH2-ND2 3.28Å
153L98.5Very high97.9Very high3 Ų323.3 Ų23.32%0.01614%0.144CC..  trans-86.5146.9-179.8-57.7-177.4000109.9T35 H116 D151 Y155 H570T35-L153 HydrophobicContact CG2-CD1 3.63Å; T35-L153 HydrophobicContact CG2-CD2 4.02Å; T35-L153 HydrophobicContact CG2-CG 4.15Å; H116-L153 HydrophobicContact CB-CB 4.02Å; H116-L153 HydrophobicContact CB-CD1 4.03Å; H116-L153 HydrophobicContact CB-CD2 4.2Å; H116-L153 HydrophobicContact CB-CG 4.32Å; D151-L153 VanDerWaalsContact C-N 3.28Å; D151-L153 PolarHBondContact O-N 2.85Å; D151-L153 VanDerWaalsContact OD1-CB 3.3Å; D151-L153 WeakPolarHBondContact OD1-CB 3.43Å; D151-L153 WeakPolarHBondContact OD1-CG 3.49Å; D151-L153 PolarHBondContact OD1-N 3.46Å; L153-Y155 HydrophobicContact CB-CE2 4.24Å; L153-H570 HydrophobicContact CD2-CB 3.61Å
154Y98.7Very high97.8Very high1 Ų121.9 Ų21.90%0.00413%0.129CC..  trans-113.8129.2162.4-176.6-90.4000107.5H116 H117 G147 D156 F174 C250 W251 Y569H116-Y154 CarbonylContact C-O 3.6Å; H116-Y154 WeakPolarHBondContact CA-O 3.48Å; H117-Y154 HydrophobicContact CB-CD1 4.4Å; H117-Y154 WeakPolarHBondContact CB-O 3.07Å; H117-Y154 PolarHBondContact N-O 3.16Å; G147-Y154 VanDerWaalsContact CA-CE2 3.4Å; Y154-D156 HydrophobicContact CD1-CB 4.49Å; Y154-F174 HydrophobicContact CD1-CD1 4.09Å; Y154-F174 HydrophobicContact CD1-CE1 4.17Å; Y154-F174 AromaticContact CE1-CD1 3.46Å; Y154-F174 HydrophobicContact CE1-CD1 3.46Å; Y154-F174 VanDerWaalsContact CE1-CD1 3.46Å; Y154-F174 AromaticContact CE1-CE1 3.98Å; Y154-F174 HydrophobicContact CE1-CE1 3.98Å; Y154-C250 HydrophobicContact CD2-CB 4.43Å; Y154-C250 HydrophobicContact CE2-CB 3.42Å; Y154-C250 VanDerWaalsContact CE2-CB 3.42Å; Y154-C250 WeakPolarHBondContact OH-CB 3.29Å; Y154-W251 HydrophobicContact CD2-CB 3.76Å; Y154-W251 HydrophobicContact CD2-CG 4.48Å; Y154-W251 HydrophobicContact CG-CB 4.36Å; Y154-Y569 HydrophobicContact CG-CE2 4.1Å
155Y98.7Very high97.7Very high22 Ų2220.7 Ų20.79%0.08612%0.123CC..EExtended strand (participates in β ladder)trans-88.9128.9173-61.4-95.4000108.5A114 H116 Q145 R146 G147 D149 L153A114-Y155 HydrophobicContact CB-CD1 4.22Å; A114-Y155 HydrophobicContact CB-CE1 3.79Å; A114-Y155 VanDerWaalsContact O-CE1 3.31Å; A114-Y155 WeakPolarHBondContact O-CE1 3.4Å; H116-Y155 HydrophobicContact CB-CD1 4.37Å; H116-Y155 HydrophobicContact CB-CE1 4.41Å; Q145-Y155 HydrophobicContact CB-CD1 4.15Å; Q145-Y155 HydrophobicContact CB-CG 3.98Å; Q145-Y155 HydrophobicContact CG-CD2 4.22Å; Q145-Y155 HydrophobicContact CG-CG 4.02Å; Q145-Y155 WeakPolarHBondContact O-CB 3.17Å; R146-Y155 CarbonylContact C-O 3.57Å; R146-Y155 WeakPolarHBondContact CA-O 3.21Å; G147-Y155 PolarHBondContact N-O 3.41Å; G147-Y155 WeakPolarHBondContact O-CD2 3.49Å; G147-Y155 PolarHBondContact O-N 2.92Å; D149-Y155 HydrophobicContact CB-CE2 4.33Å; D149-Y155 WeakPolarHBondContact OD1-CE2 3.42Å; D149-Y155 WeakPolarHBondContact OD2-CE2 3.1Å; L153-Y155 HydrophobicContact CB-CE2 4.24Å
156D97.4Very high97.7Very high0 Ų021.5 Ų21.50%013%0.127CC..EExtended strand (participates in β ladder)trans-10221.2-165.965.3-6.1000113.4H117 R125 N144 Y154 C158 Q173 F174H117-D156 HydrophobicContact CB-CB 3.97Å; H117-D156 IonicContact CD2-OD2 3.3Å; R125-D156 IonicContact CZ-OD1 3.88Å; R125-D156 IonicContact CZ-OD2 3.65Å; R125-D156 IonicContact NH1-OD1 2.7Å; R125-D156 PolarHBondContact NH1-OD1 3.15Å; R125-D156 IonicContact NH1-OD2 3.62Å; R125-D156 VanDerWaalsContact NH2-CG 3.33Å; R125-D156 IonicContact NH2-OD1 4Å; R125-D156 PolarHBondContact NH2-OD1 3.37Å; R125-D156 IonicContact NH2-OD2 3.74Å; R125-D156 PolarHBondContact NH2-OD2 3.35Å; R125-D156 VanDerWaalsContact NH2-OD2 3.12Å; N144-D156 PolarHBondContact ND2-OD1 3.28Å; Y154-D156 HydrophobicContact CD1-CB 4.49Å; D156-C158 PolarHBondContact O-N 3.04Å; D156-C158 PolarHBondContact O-SG 3.15Å; D156-Q173 CarbonylContact C-O 3.54Å; D156-Q173 VanDerWaalsContact CA-O 3.3Å; D156-Q173 WeakPolarHBondContact CA-O 3.41Å; D156-Q173 HydrophobicContact CB-CG 3.87Å; D156-Q173 CarbonylContact O-C 3.56Å; D156-Q173 WeakPolarHBondContact O-CA 3.37Å; D156-F174 HydrophobicContact CB-CE1 4.24Å
157G95.6Very high97.7Very high3 Ų319.6 Ų19.63%0.03112%0.12CC..  trans53.7-112.3174.300000112.5R125 N144 Q145 A159R125-G157 PolarHBondContact NH1-O 2.86Å; N144-G157 WeakPolarHBondContact CB-O 3.18Å; N144-G157 PolarHBondContact ND2-N 3.46Å; N144-G157 PolarHBondContact ND2-O 3.29Å; Q145-G157 WeakPolarHBondContact O-CA 3.34Å; Q145-G157 PolarHBondContact O-N 2.71Å; G157-A159 VanDerWaalsContact C-N 3.31Å
158C97.3Very high97.7Very high1 Ų119.7 Ų19.71%0.00712%0.12CC..  trans58.443-170.2-63.10000111.4Y142 D156 M160 A172 Q173 W235Y142-C158 VanDerWaalsContact CD1-O 3.28Å; Y142-C158 WeakPolarHBondContact CD1-O 3.16Å; D156-C158 PolarHBondContact O-N 3.04Å; D156-C158 PolarHBondContact O-SG 3.15Å; C158-M160 HydrophobicContact CB-CE 4.31Å; C158-M160 WeakPolarHBondContact O-CE 3.43Å; C158-M160 PolarHBondContact O-N 3.02Å; C158-A172 PolarHBondContact N-O 2.7Å; C158-Q173 VanDerWaalsContact SG-CB 3.55Å; C158-Q173 VanDerWaalsContact SG-CG 3.55Å; C158-W235 HydrophobicContact CB-CH2 4.02Å; C158-W235 HydrophobicContact CB-CZ2 4.11Å
159A97.8Very high97.7Very high20 Ų2019.9 Ų19.917%0.16512%0.122CC..  trans-56.1139.5169.200000108.9Y142 G157 R170 G171 I182Y142-A159 CarbonylContact O-C 3.31Å; Y142-A159 WeakPolarHBondContact O-CA 3.44Å; G157-A159 VanDerWaalsContact C-N 3.31Å; A159-R170 CarbonylContact O-C 3.44Å; A159-R170 WeakPolarHBondContact O-CA 3.42Å; A159-G171 PolarHBondContact O-N 2.71Å; A159-I182 HydrophobicContact CB-CG1 4.28Å
160M97.9Very high97.6Very high2 Ų221 Ų211%0.0112%0.121CC..EExtended strand (participates in β ladder)trans-153.9155.6-177.967.1-173.283.700112.3V126 I129 Y142 C158 V167 A169 W235V126-M160 HydrophobicContact CG2-CE 3.81Å; V126-M160 HydrophobicContact CG2-SD 4.33Å; I129-M160 HydrophobicContact CB-SD 4.35Å; I129-M160 HydrophobicContact CD1-CE 3.87Å; I129-M160 HydrophobicContact CD1-CG 4.07Å; I129-M160 HydrophobicContact CD1-SD 3.55Å; I129-M160 VanDerWaalsContact CD1-SD 3.55Å; I129-M160 HydrophobicContact CG2-SD 4.29Å; Y142-M160 HydrophobicContact CD1-CE 4.35Å; Y142-M160 PolarHBondContact N-O 2.8Å; Y142-M160 PolarHBondContact O-N 3.45Å; C158-M160 HydrophobicContact CB-CE 4.31Å; C158-M160 WeakPolarHBondContact O-CE 3.43Å; C158-M160 PolarHBondContact O-N 3.02Å; M160-V167 HydrophobicContact CB-CG1 4.46Å; M160-A169 VanDerWaalsContact CA-O 3.23Å; M160-A169 WeakPolarHBondContact CA-O 3.21Å; M160-A169 WeakPolarHBondContact CB-O 3.21Å; M160-W235 HydrophobicContact CB-CH2 4.47Å; M160-W235 HydrophobicContact CB-CZ3 3.96Å; M160-W235 HydrophobicContact CE-CH2 3.59Å; M160-W235 HydrophobicContact CE-CZ2 4.5Å; M160-W235 HydrophobicContact CE-CZ3 3.72Å; M160-W235 HydrophobicContact SD-CH2 4.38Å; M160-W235 HydrophobicContact SD-CZ3 3.9Å
161V98.6Very high97.7Very high12 Ų1218.2 Ų18.27%0.0739%0.092CC..EExtended strand (participates in β ladder)trans-117.3127.7168.4-173.80000107.6I139 Y140 V168 A169 A184 L186I139-V161 HydrophobicContact CG2-CG1 4.06Å; Y140-V161 WeakPolarHBondContact O-CA 3.4Å; V161-V168 HydrophobicContact CB-CG2 3.88Å; V161-V168 HydrophobicContact CG1-CG2 3.79Å; V161-V168 VanDerWaalsContact O-CG2 3.25Å; V161-V168 WeakPolarHBondContact O-CG2 3.02Å; V161-V168 PolarHBondContact O-N 3.32Å; V161-A169 HydrophobicContact CB-CB 4.25Å; V161-A169 HydrophobicContact CG2-CB 4.37Å; V161-A169 PolarHBondContact N-O 2.87Å; V161-A169 PolarHBondContact O-N 3.3Å; V161-A184 HydrophobicContact CB-CB 4.09Å; V161-A184 HydrophobicContact CG1-CB 3.98Å; V161-A184 HydrophobicContact CG2-CB 4.22Å; V161-L186 HydrophobicContact CG1-CD1 3.82Å
162A98.3Very high97.7Very high0 Ų017.6 Ų17.60%09%0.093CC..EExtended strand (participates in β ladder)trans-123.7149.917500000110.5I129 I139 Y140 E166 V167I129-A162 HydrophobicContact CG2-CB 3.87Å; I139-A162 CarbonylContact C-O 3.48Å; I139-A162 VanDerWaalsContact CA-O 3.28Å; I139-A162 WeakPolarHBondContact CA-O 3.42Å; Y140-A162 PolarHBondContact N-O 2.87Å; Y140-A162 PolarHBondContact O-N 2.85Å; A162-E166 CarbonylContact C-O 3.39Å; A162-E166 WeakPolarHBondContact CA-O 3.38Å; A162-E166 WeakPolarHBondContact CB-O 3.21Å; A162-V167 HydrophobicContact CB-CG2 4.5Å
163I98.1Very high97.7Very high15 Ų1517 Ų178%0.0779%0.092CC..EExtended strand (participates in β ladder)trans-138.7128.4174.3-175.6172.2000108.8G138 I139 G165 E166 V168 L186 D190 V191G138-I163 WeakPolarHBondContact O-CA 3.48Å; I139-I163 HydrophobicContact CD1-CD1 4.42Å; I139-I163 HydrophobicContact CG1-CB 4.29Å; I139-I163 HydrophobicContact CG1-CD1 3.92Å; I139-I163 HydrophobicContact CG1-CG1 3.95Å; I163-G165 PolarHBondContact O-N 3.45Å; I163-E166 PolarHBondContact N-O 3.06Å; I163-E166 PolarHBondContact O-N 3.27Å; I163-V168 HydrophobicContact CG2-CG1 3.71Å; I163-L186 HydrophobicContact CB-CD1 4.27Å; I163-L186 HydrophobicContact CD1-CB 4.37Å; I163-L186 HydrophobicContact CD1-CD1 4.41Å; I163-L186 HydrophobicContact CG2-CD2 4.27Å; I163-D190 HydrophobicContact CD1-CB 4.14Å; I163-V191 HydrophobicContact CD1-CG2 4.05Å; I163-V191 HydrophobicContact CG1-CG2 4.19Å
164N96.8Very high97.7Very high24 Ų2417.7 Ų17.713%0.1289%0.094CC..THydrogen-bonded Turntrans49.635.4172-60.2-22.1000115.2G137 G138 D190 Y194G137-N164 WeakPolarHBondContact CA-OD1 3.46Å; G138-N164 PolarHBondContact N-OD1 3.22Å; G138-N164 PolarHBondContact O-N 2.9Å; G138-N164 VanDerWaalsContact O-N 3.07Å; N164-D190 PolarHBondContact ND2-O 3.09Å; N164-Y194 HydrophobicContact CB-CD1 3.94Å; N164-Y194 HydrophobicContact CB-CD2 3.78Å; N164-Y194 HydrophobicContact CB-CE1 4.09Å; N164-Y194 HydrophobicContact CB-CE2 3.92Å; N164-Y194 HydrophobicContact CB-CG 3.78Å; N164-Y194 VanDerWaalsContact CG-CG 3.49Å; N164-Y194 VanDerWaalsContact ND2-CB 3.27Å; N164-Y194 WeakPolarHBondContact ND2-CB 3.36Å
165G96.3Very high97.6Very high2 Ų218.9 Ų18.92%0.02110%0.103CC..THydrogen-bonded Turntrans96.6-9.2-18000000115.7K130 T133 T134 I163K130-G165 WeakPolarHBondContact CE-O 3.19Å; T133-G165 WeakPolarHBondContact OG1-CA 3.43Å; T133-G165 PolarHBondContact OG1-N 3.48Å; T134-G165 WeakPolarHBondContact OG1-CA 3.28Å; I163-G165 PolarHBondContact O-N 3.45Å
166E97.7Very high97.6Very high88 Ų8818.7 Ų18.741%0.41110%0.103SC..EExtended strand (participates in β ladder)trans-108.2142.9-179.9-66.4-54146.800112.2K130 A162 I163 P232K130-E166 IonicContact NZ-OE2 2.73Å; A162-E166 CarbonylContact C-O 3.39Å; A162-E166 WeakPolarHBondContact CA-O 3.38Å; A162-E166 WeakPolarHBondContact CB-O 3.21Å; I163-E166 PolarHBondContact N-O 3.06Å; I163-E166 PolarHBondContact O-N 3.27Å; E166-P232 HydrophobicContact CB-CB 4.03Å; E166-P232 HydrophobicContact CB-CG 4.08Å; E166-P232 HydrophobicContact CG-CB 4.28Å; E166-P232 HydrophobicContact CG-CG 4.25Å
167V98.1Very high97.6Very high3 Ų321.8 Ų21.82%0.01812%0.12CC..EExtended strand (participates in β ladder)trans-89.8131.4173179.60000108V126 K130 M160 A162 A169 P232 I233 W235V126-V167 HydrophobicContact CG1-CG2 4.36Å; K130-V167 HydrophobicContact CD-CG2 4.26Å; K130-V167 HydrophobicContact CG-CG2 4.04Å; M160-V167 HydrophobicContact CB-CG1 4.46Å; A162-V167 HydrophobicContact CB-CG2 4.5Å; V167-A169 WeakPolarHBondContact CG1-O 3.38Å; V167-P232 WeakPolarHBondContact O-CA 3.17Å; V167-I233 HydrophobicContact CB-CG1 4.48Å; V167-I233 HydrophobicContact CG1-CD1 4.31Å; V167-I233 HydrophobicContact CG1-CG1 4.14Å; V167-I233 VanDerWaalsContact O-CG1 3.31Å; V167-I233 WeakPolarHBondContact O-CG1 3.23Å; V167-I233 PolarHBondContact O-N 3.08Å; V167-W235 HydrophobicContact CG1-CE3 4.09Å; V167-W235 HydrophobicContact CG1-CZ3 4.25Å; V167-W235 HydrophobicContact CG2-CE3 4.48Å
168V98.1Very high97.5Very high6 Ų626.1 Ų26.14%0.03614%0.143CC..EExtended strand (participates in β ladder)trans-114-20.9-177.7-68.30000112.7V161 I163 A184 L186 H230V161-V168 HydrophobicContact CB-CG2 3.88Å; V161-V168 HydrophobicContact CG1-CG2 3.79Å; V161-V168 VanDerWaalsContact O-CG2 3.25Å; V161-V168 WeakPolarHBondContact O-CG2 3.02Å; V161-V168 PolarHBondContact O-N 3.32Å; I163-V168 HydrophobicContact CG2-CG1 3.71Å; V168-A184 HydrophobicContact CG2-CB 3.97Å; V168-L186 HydrophobicContact CB-CD2 4.34Å; V168-L186 HydrophobicContact CG1-CD2 4.18Å; V168-L186 HydrophobicContact CG2-CD1 4.23Å; V168-L186 HydrophobicContact CG2-CD2 3.96Å; V168-H230 HydrophobicContact CB-CB 4.21Å
169A97.8Very high97.5Very high9 Ų931.7 Ų31.77%0.07418%0.176CC..EExtended strand (participates in β ladder)trans-150.3144.7176.100000110.4M160 V161 V167 I182 A184M160-A169 VanDerWaalsContact CA-O 3.23Å; M160-A169 WeakPolarHBondContact CA-O 3.21Å; M160-A169 WeakPolarHBondContact CB-O 3.21Å; V161-A169 HydrophobicContact CB-CB 4.25Å; V161-A169 HydrophobicContact CG2-CB 4.37Å; V161-A169 PolarHBondContact N-O 2.87Å; V161-A169 PolarHBondContact O-N 3.3Å; V167-A169 WeakPolarHBondContact CG1-O 3.38Å; A169-I182 HydrophobicContact CB-CG2 3.34Å; A169-A184 HydrophobicContact CB-CB 4.23Å
170R96.9Very high97.5Very high97 Ų9734.1 Ų34.137%0.36618%0.184SC..EExtended strand (participates in β ladder)trans-141.9143.8-18070.3-179.5-175.5153.31.9111.2A159 I182 I233 W235 M236A159-R170 CarbonylContact O-C 3.44Å; A159-R170 WeakPolarHBondContact O-CA 3.42Å; R170-I182 WeakPolarHBondContact O-CD1 3.09Å; R170-I233 HydrophobicContact CB-CD1 4.18Å; R170-I233 HydrophobicContact CG-CD1 3.76Å; R170-W235 HydrophobicContact CB-CE3 4.02Å; R170-W235 HydrophobicContact CB-CH2 3.86Å; R170-W235 HydrophobicContact CB-CZ3 3.46Å; R170-W235 VanDerWaalsContact CB-CZ3 3.46Å; R170-M236 PolarHBondContact NH1-O 2.8Å
171G97.3Very high97.5Very high7 Ų739.4 Ų39.47%0.07222%0.216CC..  trans-98.9167168.500000112A159 E180A159-G171 PolarHBondContact O-N 2.71Å; G171-E180 WeakPolarHBondContact CA-OE1 3.39Å; G171-E180 WeakPolarHBondContact CA-OE2 3.44Å
172A97.3Very high97.4Very high36 Ų3641.1 Ų41.130%0.29823%0.225SC..  trans-68147.3-17800000112.3C158 E180C158-A172 PolarHBondContact N-O 2.7Å; A172-E180 PolarHBondContact N-OE1 3.28Å; A172-E180 PolarHBondContact N-OE2 2.84Å; A172-E180 VanDerWaalsContact N-OE2 3.1Å
173Q98.1Very high97.3Very high7 Ų746 Ų463%0.03326%0.255CS..SBendtrans-76-41.7172.4-170.1173.3-4.500111D156 C158 H238 E243D156-Q173 CarbonylContact C-O 3.54Å; D156-Q173 VanDerWaalsContact CA-O 3.3Å; D156-Q173 WeakPolarHBondContact CA-O 3.41Å; D156-Q173 HydrophobicContact CB-CG 3.87Å; D156-Q173 CarbonylContact O-C 3.56Å; D156-Q173 WeakPolarHBondContact O-CA 3.37Å; C158-Q173 VanDerWaalsContact SG-CB 3.55Å; C158-Q173 VanDerWaalsContact SG-CG 3.55Å; Q173-H238 PolarHBondContact OE1-CD2 2.82Å; Q173-E243 PolarHBondContact NE2-OE1 2.95Å
174F98.4Very high97.3Very high16 Ų1646.8 Ų46.87%0.0726%0.263CS..SBendtrans-132.5130.4179.3-47.2-75.9000108.8H117 Y154 D156 E243 L246H117-F174 AromaticContact CD2-CZ 3.77Å; H117-F174 AromaticContact NE2-CZ 3.72Å; Y154-F174 HydrophobicContact CD1-CD1 4.09Å; Y154-F174 HydrophobicContact CD1-CE1 4.17Å; Y154-F174 AromaticContact CE1-CD1 3.46Å; Y154-F174 HydrophobicContact CE1-CD1 3.46Å; Y154-F174 VanDerWaalsContact CE1-CD1 3.46Å; Y154-F174 AromaticContact CE1-CE1 3.98Å; Y154-F174 HydrophobicContact CE1-CE1 3.98Å; D156-F174 HydrophobicContact CB-CE1 4.24Å; F174-E243 HydrophobicContact CE2-CB 4.22Å; F174-E243 HydrophobicContact CE2-CG 4.05Å; F174-E243 HydrophobicContact CZ-CB 4.22Å; F174-E243 HydrophobicContact CZ-CG 4.26Å; F174-L246 HydrophobicContact CB-CB 3.73Å; F174-L246 HydrophobicContact CD2-CB 3.52Å; F174-L246 HydrophobicContact CD2-CD1 3.85Å; F174-L246 HydrophobicContact CD2-CG 4.34Å; F174-L246 HydrophobicContact CE2-CB 4.24Å; F174-L246 HydrophobicContact CG-CB 3.67Å
175S97.4Very high97.3Very high27 Ų2748.2 Ų48.219%0.18927%0.273CS..  trans-163.6158.9175151.80000109.1R146 D177R146-S175 VanDerWaalsContact CZ-CB 3.46Å; R146-S175 PolarHBondContact NH2-OG 2.79Å; R146-S175 VanDerWaalsContact NH2-OG 3.12Å; S175-D177 PolarHBondContact OG-N 2.8Å; S175-D177 PolarHBondContact OG-OD2 3.3Å
176L98.1Very high97.3Very high17 Ų1750 Ų509%0.08928%0.281CS..SBendtrans-88.7-0.6175.8-50.7-173.9000113.2C250 W253 L287 L288 A291 V299L176-C250 HydrophobicContact CD2-CB 4.26Å; L176-W253 HydrophobicContact CD2-CB 4.31Å; L176-W253 HydrophobicContact CD2-CG 4.21Å; L176-L287 HydrophobicContact CD1-CB 3.95Å; L176-L287 HydrophobicContact CG-CB 4.39Å; L176-L288 HydrophobicContact CD1-CD2 3.62Å; L176-L288 HydrophobicContact CD1-CG 4.05Å; L176-A291 HydrophobicContact CD1-CB 4.07Å; L176-V299 HydrophobicContact CB-CG2 3.84Å
177D97.1Very high97.1Very high66 Ų6649.3 Ų49.335%0.35328%0.281SS..  trans-76.1129.5176.6-35.9-59.7000110.4R146 S175 V179 N296R146-D177 VanDerWaalsContact NH2-CB 3.34Å; R146-D177 PolarHBondContact NH2-O 3.41Å; R146-D177 IonicContact NH2-OD2 2.97Å; S175-D177 PolarHBondContact OG-N 2.8Å; S175-D177 PolarHBondContact OG-OD2 3.3Å; D177-V179 PolarHBondContact O-N 2.69Å; D177-N296 PolarHBondContact OD1-ND2 3.35Å
178D95.1Very high97Very high94 Ų9450.6 Ų50.650%0.50329%0.287SS..SBendtrans-69-24.7176.1-82.2-13.7000112.1R257D178-R257 IonicContact OD1-CZ 3.78Å; D178-R257 IonicContact OD1-NH1 3.03Å; D178-R257 PolarHBondContact OD1-NH1 3.03Å; D178-R257 IonicContact OD1-NH2 3.85Å; D178-R257 PolarHBondContact OD1-NH2 3.37Å; D178-R257 IonicContact OD2-NH1 3.51Å; D178-R257 PolarHBondContact OD2-NH1 3.4Å
179V96.9Very high96.8Very high117 Ų11755.9 Ų55.971%0.70931%0.311SS*.  trans-137126.7179.2-177.20000110.1D177 V181D177-V179 PolarHBondContact O-N 2.69Å; V179-V181 HydrophobicContact CG1-CG2 4.16Å
180E96.9Very high96.7Very high72 Ų7259.1 Ų59.134%0.33633%0.328SS..  trans-126.7134.9168.7179.5-176.6-126.800108.2R146 G171 A172 I182R146-E180 IonicContact CZ-OE2 2.84Å; R146-E180 IonicContact NH1-OE1 3.36Å; R146-E180 PolarHBondContact NH1-OE1 3.1Å; R146-E180 IonicContact NH1-OE2 3.66Å; R146-E180 PolarHBondContact NH1-OE2 3.48Å; G171-E180 WeakPolarHBondContact CA-OE1 3.39Å; G171-E180 WeakPolarHBondContact CA-OE2 3.44Å; A172-E180 PolarHBondContact N-OE1 3.28Å; A172-E180 PolarHBondContact N-OE2 2.84Å; A172-E180 VanDerWaalsContact N-OE2 3.1Å; E180-I182 HydrophobicContact CG-CD1 4.05Å; E180-I182 HydrophobicContact CG-CG1 4.47Å
181V97.8Very high96.6Very high113 Ų11354.5 Ų54.569%0.68531%0.31SS*.  trans-123.8126.5177.6-178.40000108.4V179 T183V179-V181 HydrophobicContact CG1-CG2 4.16Å; V181-T183 HydrophobicContact CG1-CG2 4.31Å
182I96.9Very high96.4Very high48 Ų4856.4 Ų56.425%0.24632%0.322CS..  trans-109.8132.3176.2-54.7-59.7000108.4A159 A169 R170 E180A159-I182 HydrophobicContact CB-CG1 4.28Å; A169-I182 HydrophobicContact CB-CG2 3.34Å; R170-I182 WeakPolarHBondContact O-CD1 3.09Å; E180-I182 HydrophobicContact CG-CD1 4.05Å; E180-I182 HydrophobicContact CG-CG1 4.47Å
183T96.9Very high96.2Very high103 Ų10358.3 Ų58.363%0.63233%0.333SS*.  trans-123.9151.3178.454.90000110V181V181-T183 HydrophobicContact CG1-CG2 4.31Å
184A97.1Very high96.1Very high31 Ų3160.7 Ų60.726%0.25634%0.342SS..  trans-145.5138.6169.200000109.2V161 V168 A169 L186 H230V161-A184 HydrophobicContact CB-CB 4.09Å; V161-A184 HydrophobicContact CG1-CB 3.98Å; V161-A184 HydrophobicContact CG2-CB 4.22Å; V168-A184 HydrophobicContact CG2-CB 3.97Å; A169-A184 HydrophobicContact CB-CB 4.23Å; A184-L186 HydrophobicContact CB-CD1 4.41Å; A184-L186 HydrophobicContact CB-CD2 4.49Å; A184-L186 HydrophobicContact CB-CG 4.23Å; A184-H230 HydrophobicContact CB-CB 4.31Å
185T96.8Very high95.8Very high54 Ų5462 Ų6233%0.33135%0.347SS..  trans-97.7121.2171-52.10000107.8L227 P228 T229 H230T185-L227 HydrophobicContact CG2-CB 4.01Å; T185-P228 WeakPolarHBondContact CB-O 3.35Å; T185-T229 WeakPolarHBondContact O-CA 3.44Å; T185-H230 PolarHBondContact N-ND1 2.89Å; T185-H230 PolarHBondContact O-N 2.9Å
186L96Very high95.3Very high38 Ų3862.8 Ų62.820%0.19936%0.359CS..  trans-135.8147.5-173.3-58.9173.8000110.1I139 V161 I163 V168 A184 H230I139-L186 HydrophobicContact CD1-CB 4.08Å; I139-L186 HydrophobicContact CD1-CD1 3.95Å; I139-L186 HydrophobicContact CG1-CD1 4Å; I139-L186 HydrophobicContact CG2-CD1 3.76Å; V161-L186 HydrophobicContact CG1-CD1 3.82Å; I163-L186 HydrophobicContact CB-CD1 4.27Å; I163-L186 HydrophobicContact CD1-CB 4.37Å; I163-L186 HydrophobicContact CD1-CD1 4.41Å; I163-L186 HydrophobicContact CG2-CD2 4.27Å; V168-L186 HydrophobicContact CB-CD2 4.34Å; V168-L186 HydrophobicContact CG1-CD2 4.18Å; V168-L186 HydrophobicContact CG2-CD1 4.23Å; V168-L186 HydrophobicContact CG2-CD2 3.96Å; A184-L186 HydrophobicContact CB-CD1 4.41Å; A184-L186 HydrophobicContact CB-CD2 4.49Å; A184-L186 HydrophobicContact CB-CG 4.23Å; L186-H230 HydrophobicContact CD2-CB 4.44Å
187D95Very high94.9Very high74 Ų7469.2 Ų69.240%0.39639%0.389SS..  trans-86.9128.1173.5-164.5-20.2000109.6E189 D190 T229D187-E189 PolarHBondContact O-N 3.34Å; D187-E189 WeakPolarHBondContact OD1-CB 3.42Å; D187-E189 PolarHBondContact OD1-N 3.22Å; D187-D190 WeakPolarHBondContact O-CB 3.47Å; D187-D190 PolarHBondContact O-N 2.98Å; D187-T229 HydrophobicContact CB-CG2 4.45Å
188L95.2Very high93.9Very high31 Ų3170.1 Ų70.116%0.16239%0.393CS..Hα-helixtrans-69.5-27.2175.8-70.1172.6000111.3T81 I108 I139 D190 V191 C192T81-L188 HydrophobicContact CG2-CD1 4.43Å; I108-L188 HydrophobicContact CD1-CD2 4.28Å; I108-L188 HydrophobicContact CG1-CD2 4.39Å; I139-L188 HydrophobicContact CD1-CD2 3.96Å; L188-D190 PolarHBondContact O-N 3.43Å; L188-V191 WeakPolarHBondContact O-CB 3.37Å; L188-V191 PolarHBondContact O-N 3.29Å; L188-C192 PolarHBondContact O-N 2.73Å
189E94.1Very high92.3Very high116 Ų11670.4 Ų70.454%0.54240%0.401SS..Hα-helixtrans-67.7-21.5178-64.6-61.9166.500112.5D187 V191 C192 S193D187-E189 PolarHBondContact O-N 3.34Å; D187-E189 WeakPolarHBondContact OD1-CB 3.42Å; D187-E189 PolarHBondContact OD1-N 3.22Å; E189-V191 VanDerWaalsContact C-N 3.3Å; E189-V191 PolarHBondContact O-N 3.45Å; E189-C192 PolarHBondContact O-N 3.05Å; E189-S193 WeakPolarHBondContact O-CB 3.34Å; E189-S193 PolarHBondContact O-N 3.21Å; E189-S193 PolarHBondContact O-OG 3.07Å
190D95.5Very high90.6Very high77 Ų7769.5 Ų69.541%0.41239%0.389SS..Hα-helixtrans-65.2-35.5170.4-71.1-24.7000111.2I163 N164 D187 L188 Y194I163-D190 HydrophobicContact CD1-CB 4.14Å; N164-D190 PolarHBondContact ND2-O 3.09Å; D187-D190 WeakPolarHBondContact O-CB 3.47Å; D187-D190 PolarHBondContact O-N 2.98Å; L188-D190 PolarHBondContact O-N 3.43Å; D190-Y194 WeakPolarHBondContact O-CB 3.48Å; D190-Y194 PolarHBondContact O-N 2.69Å
191V95.4Very high88.5Confident0 Ų070.7 Ų70.70%040%0.404CS..Hα-helixtrans-69.5-46.9174.5176.20000110.4E107 I139 I163 L188 E189 Y194 R195E107-V191 HydrophobicContact CB-CG1 4.31Å; E107-V191 HydrophobicContact CG-CG1 4.08Å; I139-V191 HydrophobicContact CD1-CG2 4.35Å; I139-V191 HydrophobicContact CG1-CG2 3.92Å; I163-V191 HydrophobicContact CD1-CG2 4.05Å; I163-V191 HydrophobicContact CG1-CG2 4.19Å; L188-V191 WeakPolarHBondContact O-CB 3.37Å; L188-V191 PolarHBondContact O-N 3.29Å; E189-V191 VanDerWaalsContact C-N 3.3Å; E189-V191 PolarHBondContact O-N 3.45Å; V191-Y194 PolarHBondContact O-N 3.23Å; V191-R195 WeakPolarHBondContact O-CB 3.33Å; V191-R195 WeakPolarHBondContact O-CG 3.3Å; V191-R195 PolarHBondContact O-N 3.23Å
192C92.1Very high86.5Confident48 Ų4873.3 Ų73.332%0.32441%0.413SS..Hα-helixtrans-58.6-48.6178.3-660000111.2L188 E189 R195 G196L188-C192 PolarHBondContact O-N 2.73Å; E189-C192 PolarHBondContact O-N 3.05Å; C192-R195 PolarHBondContact O-N 3.05Å; C192-G196 PolarHBondContact O-N 3.47Å
193S94.1Very high84.5Confident76 Ų7677.8 Ų77.853%0.53143%0.434SS..Hα-helixtrans-65.3-43.9-179.7-600000111.8E189 R195 G196 E197E189-S193 WeakPolarHBondContact O-CB 3.34Å; E189-S193 PolarHBondContact O-N 3.21Å; E189-S193 PolarHBondContact O-OG 3.07Å; S193-R195 PolarHBondContact O-N 3.49Å; S193-G196 CarbonylContact O-C 3.59Å; S193-G196 PolarHBondContact O-N 2.78Å; S193-E197 PolarHBondContact O-N 2.98Å
194Y94.5Very high82.2Confident56 Ų5682.1 Ų82.122%0.2245%0.447CS..Hα-helixtrans-61.2-43.8177-175.4-94.9000112.4T134 N164 D190 V191 G196 L198T134-Y194 PolarHBondContact O-OH 3.46Å; N164-Y194 HydrophobicContact CB-CD1 3.94Å; N164-Y194 HydrophobicContact CB-CD2 3.78Å; N164-Y194 HydrophobicContact CB-CE1 4.09Å; N164-Y194 HydrophobicContact CB-CE2 3.92Å; N164-Y194 HydrophobicContact CB-CG 3.78Å; N164-Y194 VanDerWaalsContact CG-CG 3.49Å; N164-Y194 VanDerWaalsContact ND2-CB 3.27Å; N164-Y194 WeakPolarHBondContact ND2-CB 3.36Å; D190-Y194 WeakPolarHBondContact O-CB 3.48Å; D190-Y194 PolarHBondContact O-N 2.69Å; V191-Y194 PolarHBondContact O-N 3.23Å; Y194-G196 VanDerWaalsContact C-N 3.34Å; Y194-L198 HydrophobicContact CD1-CD1 4.21Å; Y194-L198 HydrophobicContact CE1-CD1 3.85Å; Y194-L198 WeakPolarHBondContact O-CG 3.34Å; Y194-L198 PolarHBondContact O-N 3.1Å
195R91.7Very high80Confident43 Ų4383.2 Ų83.216%0.16246%0.462CS..Hα-helixtrans-68-35.7174.8-72.4-179.7171.5169.23.7112.1V106 S136 G137 V191 C192 S193 L198V106-R195 VanDerWaalsContact O-CZ 3.28Å; V106-R195 PolarHBondContact O-NH1 3.5Å; V106-R195 PolarHBondContact O-NH2 3.01Å; S136-R195 PolarHBondContact O-NE 2.92Å; S136-R195 PolarHBondContact O-NH2 2.96Å; G137-R195 PolarHBondContact O-NH2 3.05Å; V191-R195 WeakPolarHBondContact O-CB 3.33Å; V191-R195 WeakPolarHBondContact O-CG 3.3Å; V191-R195 PolarHBondContact O-N 3.23Å; C192-R195 PolarHBondContact O-N 3.05Å; S193-R195 PolarHBondContact O-N 3.49Å; R195-L198 PolarHBondContact O-N 2.94Å
196G88.4Confident77.9Confident44 Ų4490.6 Ų90.645%0.45449%0.493SS..Hα-helixtrans-65.3-41175.900000112.8C192 S193 Y194 L198 C199C192-G196 PolarHBondContact O-N 3.47Å; S193-G196 CarbonylContact O-C 3.59Å; S193-G196 PolarHBondContact O-N 2.78Å; Y194-G196 VanDerWaalsContact C-N 3.34Å; G196-L198 VanDerWaalsContact C-N 3.3Å; G196-L198 PolarHBondContact O-N 2.87Å; G196-C199 PolarHBondContact O-N 3.41Å; G196-C199 PolarHBondContact O-SG 2.71Å
197E88.2Confident76.3Confident153 Ų15394.5 Ų94.572%0.71551%0.51SS*.Hα-helixtrans-58.3-43.8175.3-177.3-177172.600111.3S193 C199S193-E197 PolarHBondContact O-N 2.98Å; E197-C199 PolarHBondContact O-N 2.88Å; E197-C199 VanDerWaalsContact O-N 3.13Å
198L76Confident75.4Confident85 Ų8597.6 Ų97.645%0.44552%0.52SS..THydrogen-bonded Turntrans-68-10.6178.9-66173.4000113.4Y194 R195 G196 Q200Y194-L198 HydrophobicContact CD1-CD1 4.21Å; Y194-L198 HydrophobicContact CE1-CD1 3.85Å; Y194-L198 WeakPolarHBondContact O-CG 3.34Å; Y194-L198 PolarHBondContact O-N 3.1Å; R195-L198 PolarHBondContact O-N 2.94Å; G196-L198 VanDerWaalsContact C-N 3.3Å; G196-L198 PolarHBondContact O-N 2.87Å; L198-Q200 VanDerWaalsContact C-N 3.28Å; L198-Q200 HydrophobicContact CB-CG 4.43Å; L198-Q200 PolarHBondContact O-N 3.49Å; L198-Q200 VanDerWaalsContact O-N 3.15Å
199C62.8Low74.7Confident99 Ų99100.4 Ų100.467%0.66954%0.54SS*.THydrogen-bonded Turntrans4054.3178-73.40000112.2G196 E197 P201G196-C199 PolarHBondContact O-N 3.41Å; G196-C199 PolarHBondContact O-SG 2.71Å; E197-C199 PolarHBondContact O-N 2.88Å; E197-C199 VanDerWaalsContact O-N 3.13Å; C199-P201 WeakPolarHBondContact O-CD 3.28Å
200Q61.3Low74.3Confident98 Ų9895.2 Ų95.246%0.45852%0.517SS..  trans-65110.1179.6-67.1-172.14.900108.2L198 L202L198-Q200 VanDerWaalsContact C-N 3.28Å; L198-Q200 HydrophobicContact CB-CG 4.43Å; L198-Q200 PolarHBondContact O-N 3.49Å; L198-Q200 VanDerWaalsContact O-N 3.15Å; Q200-L202 PolarHBondContact O-N 3.28Å
201P53.2Low74.1Confident98 Ų9895.6 Ų95.664%0.63652%0.516SS*.  trans-57.7142.2171.126-31.7000106.7C199 M203C199-P201 WeakPolarHBondContact O-CD 3.28Å; P201-M203 VanDerWaalsContact C-N 3.34Å; P201-M203 PolarHBondContact O-N 2.96Å
202L54.2Low74.1Confident168 Ų168100.8 Ų100.888%0.8854%0.535SS*.  trans-40.5104.5172.1-109.495.2000107.4Q200 E204Q200-L202 PolarHBondContact O-N 3.28Å; L202-E204 VanDerWaalsContact C-N 3.29Å; L202-E204 PolarHBondContact O-N 3.24Å
203M55Low74.3Confident141 Ų14199.7 Ų99.770%0.69553%0.526SS*.  trans-69.1103.5174.3-75.6-119.1135.500103.2P201 G205P201-M203 VanDerWaalsContact C-N 3.34Å; P201-M203 PolarHBondContact O-N 2.96Å; M203-G205 PolarHBondContact O-N 3.28Å
204E48.6Very low74.5Confident194 Ų194105.2 Ų105.291%0.90754%0.54SS*.  trans-58.879.1172.5-76.4-174.8154.300108.4L202L202-E204 VanDerWaalsContact C-N 3.29Å; L202-E204 PolarHBondContact O-N 3.24Å
205G51.9Low74.6Confident55 Ų55103.1 Ų103.157%0.56753%0.534SS*.  trans-100.9113.2177.600000108.1M203 Q207M203-G205 PolarHBondContact O-N 3.28Å; G205-Q207 PolarHBondContact O-N 2.77Å
206Q52.2Low74.9Confident209 Ų209107.6 Ų107.698%0.97756%0.561SS**  trans-61.827.2175.3-64.3176.4-26.500114.3
207Q63.8Low75.3Confident120 Ų120109.4 Ų109.456%0.56156%0.556SS**PPolyproline II helixtrans-100.6142.5-174.9-68.1-165.74.400111.8Q100 G205Q100-Q207 VanDerWaalsContact CD-OE1 3.3Å; Q100-Q207 VanDerWaalsContact OE1-OE1 3.12Å; G205-Q207 PolarHBondContact O-N 2.77Å
208K74.5Confident75.7Confident138 Ų138104.7 Ų104.760%0.654%0.54SS*.PPolyproline II helixtrans-63.3127.9177.9-171.3179.7-179.3-175.30109
209P81.4Confident76.6Confident90 Ų90104.6 Ų104.658%0.58454%0.539SS*.PPolyproline II helixtrans-61.4151.218024.8-34000111.2H211P209-H211 PolarHBondContact O-N 2.94Å
210C84.6Confident78.1Confident8 Ų8102.4 Ų102.45%0.05453%0.525CS..PPolyproline II helixtrans-51.1133.4169.3-77.40000110.7R49 V75 D104 R212R49-C210 PolarHBondContact NH1-SG 2.85Å; R49-C210 PolarHBondContact NH2-SG 3.04Å; V75-C210 HydrophobicContact CG1-CB 4.2Å; V75-C210 HydrophobicContact CG2-CB 4.05Å; D104-C210 VanDerWaalsContact OD2-CB 3.24Å; D104-C210 WeakPolarHBondContact OD2-CB 3.36Å; D104-C210 PolarHBondContact OD2-N 3.49Å; D104-C210 PolarHBondContact OD2-SG 3.12Å; C210-R212 PolarHBondContact O-N 3.03Å
211H91.8Very high79.4Confident85 Ų85100.6 Ų100.639%0.39452%0.523SS..EExtended strand (participates in β ladder)trans-63.1135162.8-173.279.1000108.8V51 C74 V75 P209 I213V51-H211 HydrophobicContact CG1-CB 4.43Å; C74-H211 WeakPolarHBondContact CA-O 3.41Å; C74-H211 HydrophobicContact CB-CB 3.8Å; C74-H211 WeakPolarHBondContact CB-O 3.48Å; V75-H211 PolarHBondContact N-O 3.39Å; P209-H211 PolarHBondContact O-N 2.94Å; H211-I213 WeakPolarHBondContact NE2-CD1 3.42Å
212R95.5Very high80.7Confident108 Ų108100.9 Ų100.941%0.40853%0.528SS..EExtended strand (participates in β ladder)trans-115.8116.4-176.5-69.9-178.3170.6-1262.7110V75 D104 C210 K214V75-R212 HydrophobicContact CG2-CG 3.75Å; V75-R212 WeakPolarHBondContact O-CA 3.43Å; D104-R212 PolarHBondContact O-NH2 2.85Å; C210-R212 PolarHBondContact O-N 3.03Å; R212-K214 PolarHBondContact O-N 2.76Å
213I97.1Very high82.1Confident25 Ų2598.9 Ų98.913%0.12852%0.518CS..EExtended strand (participates in β ladder)trans-82.8114.5171-55.9-56.1000107.8P70 V75 L76 S77 H211 V215P70-I213 HydrophobicContact CB-CD1 3.91Å; P70-I213 HydrophobicContact CB-CG1 4.47Å; P70-I213 HydrophobicContact CG-CD1 3.65Å; P70-I213 HydrophobicContact CG-CG1 4.34Å; V75-I213 PolarHBondContact O-N 2.93Å; L76-I213 HydrophobicContact CD2-CB 3.88Å; L76-I213 HydrophobicContact CD2-CG1 4.46Å; L76-I213 HydrophobicContact CD2-CG2 4.2Å; S77-I213 PolarHBondContact N-O 3.04Å; H211-I213 WeakPolarHBondContact NE2-CD1 3.42Å; I213-V215 PolarHBondContact O-N 2.65Å
214K97.7Very high83.6Confident192 Ų19295.1 Ų95.184%0.83550%0.501SS*.EExtended strand (participates in β ladder)trans-72.2126.7176.3-64.4-175.4179.9-1770109.4R212R212-K214 PolarHBondContact O-N 2.76Å
215V97.9Very high85.2Confident13 Ų1391.6 Ų91.68%0.07949%0.492CS..  trans-119.1119.6178.8-173.10000107.8L17 L22 L76 S77 T78 I213 F217L17-V215 HydrophobicContact CD2-CG1 3.94Å; L22-V215 HydrophobicContact CD1-CG1 3.92Å; L22-V215 HydrophobicContact CD1-CG2 3.99Å; L22-V215 HydrophobicContact CD2-CG1 4.29Å; L22-V215 HydrophobicContact CD2-CG2 4.45Å; L76-V215 HydrophobicContact CB-CG2 4.17Å; L76-V215 HydrophobicContact CD2-CG2 4.14Å; S77-V215 PolarHBondContact O-N 2.77Å; T78-V215 HydrophobicContact CG2-CB 4.29Å; I213-V215 PolarHBondContact O-N 2.65Å; V215-F217 HydrophobicContact CG1-CB 3.86Å; V215-F217 PolarHBondContact O-N 2.77Å
216D96.9Very high86.8Confident136 Ų13699 Ų9973%0.72751%0.505SS*.  trans-76.570.2176.7-173.823.8000110.6K79K79-D216 WeakPolarHBondContact CE-OD1 3.14Å; K79-D216 IonicContact NZ-OD1 3.45Å; K79-D216 PolarHBondContact NZ-OD1 2.76Å
217F97.4Very high88.6Confident83 Ų8393.3 Ų93.336%0.36448%0.48SS..  trans-149.7153.1-177.4-169.9-111.8000109.8L17 T78 K79 V215 L219L17-F217 HydrophobicContact CD1-CD2 4.43Å; L17-F217 HydrophobicContact CD1-CE2 4.34Å; L17-F217 HydrophobicContact CD2-CB 3.69Å; L17-F217 HydrophobicContact CD2-CD1 4.2Å; L17-F217 HydrophobicContact CD2-CD2 3.78Å; L17-F217 HydrophobicContact CD2-CE2 4.49Å; L17-F217 HydrophobicContact CD2-CG 3.62Å; T78-F217 WeakPolarHBondContact CB-O 3.27Å; K79-F217 PolarHBondContact N-O 3.46Å; V215-F217 HydrophobicContact CG1-CB 3.86Å; V215-F217 PolarHBondContact O-N 2.77Å; F217-L219 HydrophobicContact CD1-CD1 3.8Å; F217-L219 HydrophobicContact CE1-CD1 4.01Å; F217-L219 HydrophobicContact CE1-CG 4.38Å
218S96.7Very high89.9Confident53 Ų5392.4 Ų92.437%0.37148%0.484SS..  trans-122.2125.7173.2-159.80000106.6D80 S220D80-S218 PolarHBondContact OD2-OG 3.35Å; S218-S220 VanDerWaalsContact C-N 3.33Å; S218-S220 WeakPolarHBondContact CB-O 2.88Å; S218-S220 PolarHBondContact OG-O 3.39Å
219L94.8Very high90.8Very high83 Ų8388.7 Ų88.744%0.43547%0.473SS..SBendtrans-75-30.5175.5-91.972.2000111.2T78 D80 T81 I83 I108 F217T78-L219 HydrophobicContact CG2-CD1 3.6Å; D80-L219 PolarHBondContact OD1-N 2.91Å; D80-L219 WeakPolarHBondContact OD2-CA 3.21Å; D80-L219 PolarHBondContact OD2-N 3.22Å; T81-L219 HydrophobicContact CG2-CD1 4.24Å; T81-L219 HydrophobicContact CG2-CD2 3.98Å; T81-L219 HydrophobicContact CG2-CG 4.49Å; I83-L219 HydrophobicContact CD1-CD1 4.18Å; I83-L219 HydrophobicContact CD1-CD2 3.91Å; I108-L219 HydrophobicContact CD1-CD2 3.97Å; F217-L219 HydrophobicContact CD1-CD1 3.8Å; F217-L219 HydrophobicContact CE1-CD1 4.01Å; F217-L219 HydrophobicContact CE1-CG 4.38Å
220S93.5Very high91.5Very high54 Ų5487.9 Ų87.938%0.37846%0.462SS..SBendtrans-106.9157.4177.6630000111.5D80 S218D80-S220 PolarHBondContact OD2-N 2.91Å; D80-S220 PolarHBondContact OD2-OG 3.03Å; S218-S220 VanDerWaalsContact C-N 3.33Å; S218-S220 WeakPolarHBondContact CB-O 2.88Å; S218-S220 PolarHBondContact OG-O 3.39Å
221S89.5Confident92.1Very high59 Ų5993.6 Ų93.641%0.41349%0.488SS..  trans-124.8150.7175.9178.20000110.4N223 D224S221-N223 PolarHBondContact O-N 3.13Å; S221-N223 PolarHBondContact OG-N 3.23Å; S221-D224 PolarHBondContact N-OD2 3.18Å; S221-D224 VanDerWaalsContact O-CB 3.29Å; S221-D224 WeakPolarHBondContact O-CB 3.5Å; S221-D224 VanDerWaalsContact O-CG 3.3Å; S221-D224 PolarHBondContact O-N 3.03Å
222S80.3Confident92.3Very high104 Ų10493.2 Ų93.273%0.72749%0.493SS*.THydrogen-bonded Turntrans-60.3-15.4174.457.50000113.8D224S222-D224 VanDerWaalsContact C-N 3.32Å
223N83.4Confident92.4Very high126 Ų12691.1 Ų91.167%0.67449%0.489SS*.THydrogen-bonded Turntrans-85.7-4.5178.5-63.4-17.4000113.1S221 V225S221-N223 PolarHBondContact O-N 3.13Å; S221-N223 PolarHBondContact OG-N 3.23Å; N223-V225 PolarHBondContact O-N 3Å
224D87.1Confident92.3Very high63 Ų6397.6 Ų97.634%0.33752%0.519SS..G310 helixtrans-80.4-1.1-172.2-64-15.9000113.5S221 S222 Y226 L227S221-D224 PolarHBondContact N-OD2 3.18Å; S221-D224 VanDerWaalsContact O-CB 3.29Å; S221-D224 WeakPolarHBondContact O-CB 3.5Å; S221-D224 VanDerWaalsContact O-CG 3.3Å; S221-D224 PolarHBondContact O-N 3.03Å; S222-D224 VanDerWaalsContact C-N 3.32Å; D224-Y226 PolarHBondContact O-N 3.07Å; D224-L227 HydrophobicContact CB-CD1 3.78Å; D224-L227 HydrophobicContact CB-CG 4.29Å; D224-L227 WeakPolarHBondContact O-CB 3.31Å; D224-L227 PolarHBondContact O-N 2.82Å
225V82.1Confident92.1Very high119 Ų11990 Ų9072%0.72149%0.485SS*.G310 helixtrans-53.8-26.5-177.2-179.80000113.4N223N223-V225 PolarHBondContact O-N 3Å
226Y85.3Confident92Very high212 Ų21295 Ų9583%0.83151%0.509SS*.G310 helixtrans-100.70.7-179.1-55.4-70.3000113.9D224D224-Y226 PolarHBondContact O-N 3.07Å
227L89.1Confident91.9Very high89 Ų8992.6 Ų92.647%0.46649%0.492SS..SBendtrans-73.9124.8178.5-66.4179.7000109.7T185 D224 T229T185-L227 HydrophobicContact CG2-CB 4.01Å; D224-L227 HydrophobicContact CB-CD1 3.78Å; D224-L227 HydrophobicContact CB-CG 4.29Å; D224-L227 WeakPolarHBondContact O-CB 3.31Å; D224-L227 PolarHBondContact O-N 2.82Å; L227-T229 PolarHBondContact O-N 3.49Å
228P90.6Very high92Very high100 Ų10091.9 Ų91.965%0.64949%0.489SS*.PPolyproline II helixtrans-67.6132178.327.3-33.3000110.4T185T185-P228 WeakPolarHBondContact CB-O 3.35Å
229T94Very high92.1Very high60 Ų6092.1 Ų92.137%0.36849%0.489SS..PPolyproline II helixtrans-77141.6173.755.40000110.7T185 D187 L227 Q231T185-T229 WeakPolarHBondContact O-CA 3.44Å; D187-T229 HydrophobicContact CB-CG2 4.45Å; L227-T229 PolarHBondContact O-N 3.49Å; T229-Q231 PolarHBondContact O-NE2 3.07Å; T229-Q231 PolarHBondContact OG1-NE2 3.01Å
230H96.3Very high92.2Very high73 Ų7389.9 Ų89.934%0.33848%0.479SS..PPolyproline II helixtrans-70.7133.1175.3-75.855.8000110.1V168 A184 T185 L186V168-H230 HydrophobicContact CB-CB 4.21Å; A184-H230 HydrophobicContact CB-CB 4.31Å; T185-H230 PolarHBondContact N-ND1 2.89Å; T185-H230 PolarHBondContact O-N 2.9Å; L186-H230 HydrophobicContact CD2-CB 4.44Å
231Q96.6Very high92.5Very high129 Ų12989.5 Ų89.560%0.60347%0.471SS*.PPolyproline II helixtrans-89.3153.7179.5-60.5-58.3-56.400111.1T229T229-Q231 PolarHBondContact O-NE2 3.07Å; T229-Q231 PolarHBondContact OG1-NE2 3.01Å
232P97.1Very high92.9Very high76 Ų7689.3 Ų89.349%0.49446%0.464SS..PPolyproline II helixtrans-52.9139.9173.1-29.237.3000113.1E166 V167E166-P232 HydrophobicContact CB-CB 4.03Å; E166-P232 HydrophobicContact CB-CG 4.08Å; E166-P232 HydrophobicContact CG-CB 4.28Å; E166-P232 HydrophobicContact CG-CG 4.25Å; V167-P232 WeakPolarHBondContact O-CA 3.17Å
233I97.1Very high93.8Very high64 Ų6484.6 Ų84.633%0.32843%0.431SS..  trans-119.4147.417762.2166.9000111.2V167 R170V167-I233 HydrophobicContact CB-CG1 4.48Å; V167-I233 HydrophobicContact CG1-CD1 4.31Å; V167-I233 HydrophobicContact CG1-CG1 4.14Å; V167-I233 VanDerWaalsContact O-CG1 3.31Å; V167-I233 WeakPolarHBondContact O-CG1 3.23Å; V167-I233 PolarHBondContact O-N 3.08Å; R170-I233 HydrophobicContact CB-CD1 4.18Å; R170-I233 HydrophobicContact CG-CD1 3.76Å
234Q94.5Very high94.5Very high161 Ų16178.8 Ų78.875%0.75240%0.399SS*.  trans-78.8131.6169.8-171.3175.55.300110.3M236Q234-M236 PolarHBondContact O-N 2.8Å
235W94.4Very high95.1Very high32 Ų3276 Ų7612%0.12139%0.385CS..  trans-78113.1173.2-165-71.7000110.7V126 C158 M160 V167 R170 F237V126-W235 HydrophobicContact CG1-CD2 4.26Å; V126-W235 HydrophobicContact CG1-CE3 4.17Å; V126-W235 HydrophobicContact CG1-CG 4.44Å; V126-W235 HydrophobicContact CG2-CD2 3.67Å; V126-W235 HydrophobicContact CG2-CE3 3.82Å; V126-W235 HydrophobicContact CG2-CG 4.3Å; V126-W235 HydrophobicContact CG2-CH2 3.96Å; V126-W235 HydrophobicContact CG2-CZ2 3.79Å; V126-W235 HydrophobicContact CG2-CZ3 3.96Å; C158-W235 HydrophobicContact CB-CH2 4.02Å; C158-W235 HydrophobicContact CB-CZ2 4.11Å; M160-W235 HydrophobicContact CB-CH2 4.47Å; M160-W235 HydrophobicContact CB-CZ3 3.96Å; M160-W235 HydrophobicContact CE-CH2 3.59Å; M160-W235 HydrophobicContact CE-CZ2 4.5Å; M160-W235 HydrophobicContact CE-CZ3 3.72Å; M160-W235 HydrophobicContact SD-CH2 4.38Å; M160-W235 HydrophobicContact SD-CZ3 3.9Å; V167-W235 HydrophobicContact CG1-CE3 4.09Å; V167-W235 HydrophobicContact CG1-CZ3 4.25Å; V167-W235 HydrophobicContact CG2-CE3 4.48Å; R170-W235 HydrophobicContact CB-CE3 4.02Å; R170-W235 HydrophobicContact CB-CH2 3.86Å; R170-W235 HydrophobicContact CB-CZ3 3.46Å; R170-W235 VanDerWaalsContact CB-CZ3 3.46Å; W235-F237 HydrophobicContact CB-CE2 4.14Å; W235-F237 HydrophobicContact CB-CZ 4.22Å; W235-F237 AromaticContact CD1-CD1 3.37Å; W235-F237 AromaticContact CD1-CD2 3.61Å; W235-F237 AromaticContact CD1-CE1 3.21Å; W235-F237 AromaticContact CD1-CE2 3.48Å; W235-F237 VanDerWaalsContact CD1-CE2 3.48Å; W235-F237 AromaticContact CD1-CG 3.56Å; W235-F237 AromaticContact CD1-CZ 3.27Å; W235-F237 HydrophobicContact CD2-CE1 4.49Å; W235-F237 HydrophobicContact CD2-CZ 4.5Å; W235-F237 HydrophobicContact CG-CD2 4.49Å; W235-F237 HydrophobicContact CG-CE1 4.02Å; W235-F237 HydrophobicContact CG-CE2 4.02Å; W235-F237 AromaticContact CG-CZ 3.75Å; W235-F237 HydrophobicContact CG-CZ 3.75Å; W235-F237 AromaticContact NE1-CD1 3.33Å; W235-F237 VanDerWaalsContact NE1-CD1 3.33Å; W235-F237 AromaticContact NE1-CE1 3.24Å; W235-F237 AromaticContact NE1-CG 3.94Å; W235-F237 AromaticContact NE1-CZ 3.8Å
236M94.3Very high95.9Very high119 Ų11971.8 Ų71.859%0.58636%0.358SS*.  trans-89109.4169.9-60.9-61.4-66.800109.3R170 Q234R170-M236 PolarHBondContact NH1-O 2.8Å; Q234-M236 PolarHBondContact O-N 2.8Å
237F96.7Very high96.5Very high85 Ų8561.7 Ų61.737%0.37332%0.319SS..PPolyproline II helixtrans-81.9146.1175.5-65.5-80.4000111A122 D123 V126 W235A122-F237 HydrophobicContact CB-CD1 4.25Å; A122-F237 HydrophobicContact CB-CE1 4.36Å; D123-F237 HydrophobicContact CB-CD1 4.3Å; D123-F237 HydrophobicContact CB-CE1 3.85Å; D123-F237 HydrophobicContact CB-CE2 4.47Å; D123-F237 HydrophobicContact CB-CZ 3.95Å; V126-F237 HydrophobicContact CB-CE1 4.33Å; V126-F237 HydrophobicContact CB-CZ 4.04Å; V126-F237 HydrophobicContact CG1-CZ 4.24Å; V126-F237 HydrophobicContact CG2-CE1 3.89Å; V126-F237 HydrophobicContact CG2-CZ 4.03Å; W235-F237 HydrophobicContact CB-CE2 4.14Å; W235-F237 HydrophobicContact CB-CZ 4.22Å; W235-F237 AromaticContact CD1-CD1 3.37Å; W235-F237 AromaticContact CD1-CD2 3.61Å; W235-F237 AromaticContact CD1-CE1 3.21Å; W235-F237 AromaticContact CD1-CE2 3.48Å; W235-F237 VanDerWaalsContact CD1-CE2 3.48Å; W235-F237 AromaticContact CD1-CG 3.56Å; W235-F237 AromaticContact CD1-CZ 3.27Å; W235-F237 HydrophobicContact CD2-CE1 4.49Å; W235-F237 HydrophobicContact CD2-CZ 4.5Å; W235-F237 HydrophobicContact CG-CD2 4.49Å; W235-F237 HydrophobicContact CG-CE1 4.02Å; W235-F237 HydrophobicContact CG-CE2 4.02Å; W235-F237 AromaticContact CG-CZ 3.75Å; W235-F237 HydrophobicContact CG-CZ 3.75Å; W235-F237 AromaticContact NE1-CD1 3.33Å; W235-F237 VanDerWaalsContact NE1-CD1 3.33Å; W235-F237 AromaticContact NE1-CE1 3.24Å; W235-F237 AromaticContact NE1-CG 3.94Å; W235-F237 AromaticContact NE1-CZ 3.8Å
238H98.1Very high97Very high68 Ų6857.5 Ų57.532%0.31530%0.297SS..PPolyproline II helixtrans-68143.1168.3-70.6-59.8000110.6Q173 E242 E243Q173-H238 PolarHBondContact OE1-CD2 2.82Å; H238-E242 VanDerWaalsContact CA-OE2 3.29Å; H238-E242 WeakPolarHBondContact CA-OE2 3.26Å; H238-E242 HydrophobicContact CB-CB 3.91Å; H238-E242 IonicContact ND1-OE2 3.41Å; H238-E243 HydrophobicContact CB-CG 3.78Å
239T98.3Very high97.4Very high58 Ų5852.7 Ų52.736%0.35627%0.266SS..PPolyproline II helixtrans-65.6158.7166.465.10000110Q241 E242 E243T239-Q241 PolarHBondContact O-N 3.19Å; T239-E242 PolarHBondContact N-OE2 2.8Å; T239-E242 WeakPolarHBondContact O-CB 3.38Å; T239-E242 PolarHBondContact O-N 3.36Å; T239-E242 VanDerWaalsContact O-N 3.08Å; T239-E242 VanDerWaalsContact OG1-CG 3.28Å; T239-E242 WeakPolarHBondContact OG1-CG 3.26Å; T239-E242 PolarHBondContact OG1-N 3.25Å; T239-E242 PolarHBondContact OG1-OE2 3.07Å; T239-E243 PolarHBondContact O-N 2.87Å
240P98.3Very high97.6Very high36 Ų3650 Ų5023%0.23425%0.249CC..Hα-helixtrans-56.1-34.5176.7-26.235.1000113.6R120 E243 I244R120-P240 HydrophobicContact CG-CB 4.48Å; R120-P240 HydrophobicContact CG-CG 4.09Å; P240-E243 PolarHBondContact O-N 2.7Å; P240-I244 WeakPolarHBondContact O-CD1 3.08Å; P240-I244 WeakPolarHBondContact O-CG1 3.48Å; P240-I244 PolarHBondContact O-N 2.86Å
241Q98.6Very high97.7Very high46 Ų4646.5 Ų46.522%0.21523%0.233CC..Hα-helixtrans-70.8-36.7178.8-61.576.511.500111.6T239 I244 S245 Y465T239-Q241 PolarHBondContact O-N 3.19Å; Q241-I244 PolarHBondContact O-N 2.97Å; Q241-S245 WeakPolarHBondContact O-CB 3.23Å; Q241-S245 PolarHBondContact O-N 3.46Å; Q241-Y465 HydrophobicContact CB-CD1 4.1Å; Q241-Y465 HydrophobicContact CB-CD2 3.87Å; Q241-Y465 HydrophobicContact CB-CG 3.63Å; Q241-Y465 HydrophobicContact CG-CG 4.41Å
242E98.6Very high97.8Very high56 Ų5640.3 Ų40.326%0.26220%0.204SC..Hα-helixtrans-67.2-42.2171.3-73.6166.6166.600111.8H238 T239 I244 S245 L246 Y465H238-E242 VanDerWaalsContact CA-OE2 3.29Å; H238-E242 WeakPolarHBondContact CA-OE2 3.26Å; H238-E242 HydrophobicContact CB-CB 3.91Å; H238-E242 IonicContact ND1-OE2 3.41Å; T239-E242 PolarHBondContact N-OE2 2.8Å; T239-E242 WeakPolarHBondContact O-CB 3.38Å; T239-E242 PolarHBondContact O-N 3.36Å; T239-E242 VanDerWaalsContact O-N 3.08Å; T239-E242 VanDerWaalsContact OG1-CG 3.28Å; T239-E242 WeakPolarHBondContact OG1-CG 3.26Å; T239-E242 PolarHBondContact OG1-N 3.25Å; T239-E242 PolarHBondContact OG1-OE2 3.07Å; E242-I244 PolarHBondContact O-N 2.82Å; E242-S245 WeakPolarHBondContact CA-OG 3.5Å; E242-S245 PolarHBondContact O-N 3.18Å; E242-S245 VanDerWaalsContact O-N 3.15Å; E242-S245 PolarHBondContact O-OG 2.95Å; E242-L246 WeakPolarHBondContact O-CB 3.48Å; E242-L246 VanDerWaalsContact O-CG 3.27Å; E242-L246 WeakPolarHBondContact O-CG 3.4Å; E242-L246 PolarHBondContact O-N 3.15Å; E242-Y465 HydrophobicContact CG-CE2 3.84Å; E242-Y465 WeakPolarHBondContact CG-OH 3.21Å
243E98.8Very high97.9Very high5 Ų536.8 Ų36.82%0.02318%0.181CC..Hα-helixtrans-60-38.3174.7-68.7-158.716800111.5H117 L119 R120 Q173 F174 H238 T239 P240 G247H117-E243 IonicContact CD2-OE2 3.32Å; H117-E243 IonicContact CE1-OE2 3.35Å; H117-E243 IonicContact NE2-OE2 2.83Å; H117-E243 PolarHBondContact NE2-OE2 3.35Å; L119-E243 WeakPolarHBondContact CA-OE2 3.48Å; L119-E243 HydrophobicContact CD1-CB 3.67Å; L119-E243 WeakPolarHBondContact CD1-OE2 3.38Å; R120-E243 PolarHBondContact N-OE2 3.48Å; Q173-E243 PolarHBondContact NE2-OE1 2.95Å; F174-E243 HydrophobicContact CE2-CB 4.22Å; F174-E243 HydrophobicContact CE2-CG 4.05Å; F174-E243 HydrophobicContact CZ-CB 4.22Å; F174-E243 HydrophobicContact CZ-CG 4.26Å; H238-E243 HydrophobicContact CB-CG 3.78Å; T239-E243 PolarHBondContact O-N 2.87Å; P240-E243 PolarHBondContact O-N 2.7Å; E243-G247 PolarHBondContact O-N 2.82Å
244I98.8Very high98Very high3 Ų334.2 Ų34.22%0.01517%0.168CC..Hα-helixtrans-71-35.5175.8-66.3164.3000111.8L119 P240 Q241 E242 L246 P248 I454 D458 F462L119-I244 HydrophobicContact CD1-CD1 4.47Å; L119-I244 HydrophobicContact CD1-CG1 3.96Å; L119-I244 HydrophobicContact CD2-CD1 4.16Å; L119-I244 HydrophobicContact CD2-CG1 4.28Å; P240-I244 WeakPolarHBondContact O-CD1 3.08Å; P240-I244 WeakPolarHBondContact O-CG1 3.48Å; P240-I244 PolarHBondContact O-N 2.86Å; Q241-I244 PolarHBondContact O-N 2.97Å; E242-I244 PolarHBondContact O-N 2.82Å; I244-L246 VanDerWaalsContact C-N 3.34Å; I244-P248 VanDerWaalsContact O-CD 3.32Å; I244-P248 WeakPolarHBondContact O-CD 3.33Å; I244-I454 HydrophobicContact CD1-CG2 3.91Å; I244-I454 HydrophobicContact CG1-CD1 4.21Å; I244-I454 HydrophobicContact CG1-CG2 4.39Å; I244-I454 HydrophobicContact CG2-CD1 3.88Å; I244-D458 HydrophobicContact CD1-CB 3.85Å; I244-F462 HydrophobicContact CB-CD2 4Å; I244-F462 HydrophobicContact CB-CE2 4.49Å; I244-F462 HydrophobicContact CB-CG 4.24Å; I244-F462 HydrophobicContact CD1-CB 4.32Å; I244-F462 HydrophobicContact CG2-CB 4.03Å; I244-F462 HydrophobicContact CG2-CD1 3.77Å; I244-F462 HydrophobicContact CG2-CD2 3.57Å; I244-F462 HydrophobicContact CG2-CE1 4.09Å; I244-F462 HydrophobicContact CG2-CE2 3.91Å; I244-F462 HydrophobicContact CG2-CG 3.49Å; I244-F462 VanDerWaalsContact CG2-CG 3.49Å; I244-F462 HydrophobicContact CG2-CZ 4.15Å
245S98.8Very high98.2Very high4 Ų428.9 Ų28.93%0.02814%0.141CC..Hα-helixtrans-71.6-30.7178.478.70000112.4Q241 E242 A249 S283Q241-S245 WeakPolarHBondContact O-CB 3.23Å; Q241-S245 PolarHBondContact O-N 3.46Å; E242-S245 WeakPolarHBondContact CA-OG 3.5Å; E242-S245 PolarHBondContact O-N 3.18Å; E242-S245 VanDerWaalsContact O-N 3.15Å; E242-S245 PolarHBondContact O-OG 2.95Å; S245-A249 WeakPolarHBondContact O-CB 3.4Å; S245-S283 WeakPolarHBondContact O-CB 3.5Å; S245-S283 PolarHBondContact O-OG 3.1Å
246L98.8Very high98.3Very high31 Ų3127.3 Ų27.316%0.16214%0.135CC..Hα-helixtrans-97.9-52.6-173.4-63.6173.4000113.4F174 E242 I244 A249 C250 L287F174-L246 HydrophobicContact CB-CB 3.73Å; F174-L246 HydrophobicContact CD2-CB 3.52Å; F174-L246 HydrophobicContact CD2-CD1 3.85Å; F174-L246 HydrophobicContact CD2-CG 4.34Å; F174-L246 HydrophobicContact CE2-CB 4.24Å; F174-L246 HydrophobicContact CG-CB 3.67Å; E242-L246 WeakPolarHBondContact O-CB 3.48Å; E242-L246 VanDerWaalsContact O-CG 3.27Å; E242-L246 WeakPolarHBondContact O-CG 3.4Å; E242-L246 PolarHBondContact O-N 3.15Å; I244-L246 VanDerWaalsContact C-N 3.34Å; L246-A249 WeakPolarHBondContact O-CB 3.34Å; L246-A249 PolarHBondContact O-N 3.17Å; L246-C250 PolarHBondContact O-N 3.17Å; L246-C250 PolarHBondContact O-SG 2.8Å; L246-C250 VanDerWaalsContact O-SG 3.39Å; L246-L287 HydrophobicContact CD2-CD1 4.02Å; L246-L287 HydrophobicContact CD2-CD2 3.77Å; L246-L287 HydrophobicContact CD2-CG 4.4Å
247G98.7Very high98.5Very high0 Ų022.7 Ų22.70%011%0.111CC..Hα-helixtrans-61.4-60.2-170.900000113.9E243 A249 C250 W251E243-G247 PolarHBondContact O-N 2.82Å; G247-A249 PolarHBondContact O-N 3.12Å; G247-C250 PolarHBondContact O-N 3.23Å; G247-W251 WeakPolarHBondContact O-CB 3.38Å; G247-W251 PolarHBondContact O-N 3.39Å
248P98.9Very high98.5Very high1 Ų124.7 Ų24.71%0.00612%0.116CC..Hα-helixtrans-55.8-32172.8-27.534.9000114I244 W251 L252 I280 P450 I454 Y569I244-P248 VanDerWaalsContact O-CD 3.32Å; I244-P248 WeakPolarHBondContact O-CD 3.33Å; P248-W251 PolarHBondContact O-N 3.13Å; P248-L252 WeakPolarHBondContact O-CG 3.48Å; P248-L252 PolarHBondContact O-N 3.06Å; P248-I280 HydrophobicContact CB-CD1 3.88Å; P248-I280 HydrophobicContact CB-CG1 4.33Å; P248-I280 HydrophobicContact CB-CG2 3.73Å; P248-I280 HydrophobicContact CG-CD1 4.38Å; P248-P450 HydrophobicContact CB-CB 4.26Å; P248-I454 HydrophobicContact CG-CD1 4.26Å; P248-Y569 HydrophobicContact CB-CD2 4.42Å; P248-Y569 HydrophobicContact CB-CG 4.47Å; P248-Y569 HydrophobicContact CG-CD1 3.95Å; P248-Y569 HydrophobicContact CG-CD2 4.39Å; P248-Y569 HydrophobicContact CG-CE1 3.89Å; P248-Y569 HydrophobicContact CG-CE2 4.29Å; P248-Y569 HydrophobicContact CG-CG 4.22Å
249A98.9Very high98.5Very high0 Ų023.8 Ų23.80%012%0.117CC..Hα-helixtrans-69.6-48.7178.800000112S245 L246 G247 W251 L252 W253 I280 M284 L287S245-A249 WeakPolarHBondContact O-CB 3.4Å; L246-A249 WeakPolarHBondContact O-CB 3.34Å; L246-A249 PolarHBondContact O-N 3.17Å; G247-A249 PolarHBondContact O-N 3.12Å; A249-W251 VanDerWaalsContact C-N 3.26Å; A249-W251 PolarHBondContact O-N 3.47Å; A249-L252 PolarHBondContact O-N 3.26Å; A249-W253 PolarHBondContact O-N 2.98Å; A249-I280 HydrophobicContact CB-CG2 4.18Å; A249-M284 HydrophobicContact CB-CB 3.97Å; A249-M284 WeakPolarHBondContact O-CG 3.33Å; A249-L287 HydrophobicContact CB-CD1 4.04Å
250C98.9Very high98.3Very high2 Ų223.5 Ų23.51%0.01413%0.126CC..Hα-helixtrans-60.9-37.5173-65.80000111.4Y154 L176 L246 G247 W253 D254Y154-C250 HydrophobicContact CD2-CB 4.43Å; Y154-C250 HydrophobicContact CE2-CB 3.42Å; Y154-C250 VanDerWaalsContact CE2-CB 3.42Å; Y154-C250 WeakPolarHBondContact OH-CB 3.29Å; L176-C250 HydrophobicContact CD2-CB 4.26Å; L246-C250 PolarHBondContact O-N 3.17Å; L246-C250 PolarHBondContact O-SG 2.8Å; L246-C250 VanDerWaalsContact O-SG 3.39Å; G247-C250 PolarHBondContact O-N 3.23Å; C250-W253 PolarHBondContact O-N 3.29Å; C250-D254 PolarHBondContact O-N 3.2Å
251W98.9Very high98.2Very high0 Ų024.9 Ų24.90%013%0.13CC..Hα-helixtrans-63.9-45.4175.8-177.781.7000113D151 Y154 G247 P248 A249 W253 D254 Y255 I448 P450 Y569D151-W251 PolarHBondContact O-NE1 3Å; Y154-W251 HydrophobicContact CD2-CB 3.76Å; Y154-W251 HydrophobicContact CD2-CG 4.48Å; Y154-W251 HydrophobicContact CG-CB 4.36Å; G247-W251 WeakPolarHBondContact O-CB 3.38Å; G247-W251 PolarHBondContact O-N 3.39Å; P248-W251 PolarHBondContact O-N 3.13Å; A249-W251 VanDerWaalsContact C-N 3.26Å; A249-W251 PolarHBondContact O-N 3.47Å; W251-W253 VanDerWaalsContact C-N 3.29Å; W251-W253 PolarHBondContact O-N 3.39Å; W251-D254 PolarHBondContact O-N 3.46Å; W251-Y255 AromaticContact CD2-CD2 3.88Å; W251-Y255 HydrophobicContact CD2-CD2 3.88Å; W251-Y255 HydrophobicContact CD2-CE2 4.05Å; W251-Y255 AromaticContact CE2-CD2 3.51Å; W251-Y255 AromaticContact CE2-CE2 3.19Å; W251-Y255 HydrophobicContact CE3-CD2 4.42Å; W251-Y255 HydrophobicContact CG-CD2 4.31Å; W251-Y255 HydrophobicContact CH2-CD2 4.33Å; W251-Y255 HydrophobicContact CH2-CE2 4.09Å; W251-Y255 AromaticContact CZ2-CD2 3.75Å; W251-Y255 HydrophobicContact CZ2-CD2 3.75Å; W251-Y255 AromaticContact CZ2-CE2 3.21Å; W251-Y255 HydrophobicContact CZ2-CE2 3.21Å; W251-Y255 AromaticContact CZ2-CZ 3.73Å; W251-Y255 AromaticContact NE1-CD2 3.74Å; W251-Y255 AromaticContact NE1-CE2 3.28Å; W251-Y255 VanDerWaalsContact NE1-CE2 3.28Å; W251-Y255 PolarHBondContact O-N 3.2Å; W251-I448 HydrophobicContact CH2-CB 3.84Å; W251-I448 HydrophobicContact CH2-CD1 4.39Å; W251-I448 HydrophobicContact CH2-CG2 4.14Å; W251-I448 HydrophobicContact CZ3-CB 4.27Å; W251-I448 HydrophobicContact CZ3-CD1 4.21Å; W251-P450 HydrophobicContact CE3-CB 4.46Å; W251-P450 HydrophobicContact CZ3-CB 4.26Å; W251-Y569 HydrophobicContact CB-CD2 3.66Å; W251-Y569 HydrophobicContact CB-CE2 3.71Å; W251-Y569 AromaticContact CD1-CD2 3.98Å; W251-Y569 AromaticContact CD2-CD2 3.7Å; W251-Y569 HydrophobicContact CD2-CD2 3.7Å; W251-Y569 HydrophobicContact CE3-CD2 4.08Å; W251-Y569 AromaticContact CG-CD2 3.52Å; W251-Y569 HydrophobicContact CG-CD2 3.52Å; W251-Y569 AromaticContact CG-CE2 3.99Å; W251-Y569 HydrophobicContact CG-CE2 3.99Å
252L98.9Very high98.1Very high0 Ų023 Ų230%012%0.123CC..Hα-helixtrans-61.3-39.4174.3-76-176.3000111.6P248 A249 Y255 L256 F264 I280 V281 M284 L425 I448 P450P248-L252 WeakPolarHBondContact O-CG 3.48Å; P248-L252 PolarHBondContact O-N 3.06Å; A249-L252 PolarHBondContact O-N 3.26Å; L252-Y255 PolarHBondContact O-N 2.88Å; L252-L256 WeakPolarHBondContact O-CB 3.34Å; L252-L256 PolarHBondContact O-N 2.94Å; L252-F264 HydrophobicContact CB-CE2 4.4Å; L252-F264 HydrophobicContact CB-CZ 3.97Å; L252-F264 HydrophobicContact CD2-CE1 4.17Å; L252-F264 HydrophobicContact CD2-CZ 4.14Å; L252-F264 HydrophobicContact CG-CZ 4.49Å; L252-I280 HydrophobicContact CD1-CG2 3.74Å; L252-I280 HydrophobicContact CG-CG2 4.5Å; L252-V281 HydrophobicContact CD1-CG2 3.83Å; L252-M284 HydrophobicContact CB-SD 3.97Å; L252-L425 HydrophobicContact CD2-CD2 3.95Å; L252-I448 HydrophobicContact CD2-CD1 3.64Å; L252-I448 HydrophobicContact CD2-CG1 4.45Å; L252-P450 HydrophobicContact CD1-CB 4.06Å; L252-P450 HydrophobicContact CD1-CG 4.14Å; L252-P450 HydrophobicContact CD2-CB 4.1Å; L252-P450 HydrophobicContact CD2-CG 4.36Å; L252-P450 HydrophobicContact CG-CB 4.08Å
253W98.8Very high98.1Very high1 Ų120.3 Ų20.30%0.00411%0.11CC..Hα-helixtrans-61.3-47.7176.7175.2-121.4000112.1L176 A249 C250 W251 Y255 L256 R257 M284 L288 V299 D302 V303 V306L176-W253 HydrophobicContact CD2-CB 4.31Å; L176-W253 HydrophobicContact CD2-CG 4.21Å; A249-W253 PolarHBondContact O-N 2.98Å; C250-W253 PolarHBondContact O-N 3.29Å; W251-W253 VanDerWaalsContact C-N 3.29Å; W251-W253 PolarHBondContact O-N 3.39Å; W253-Y255 VanDerWaalsContact C-N 3.33Å; W253-Y255 PolarHBondContact O-N 3.27Å; W253-L256 HydrophobicContact CE3-CD2 4.48Å; W253-L256 HydrophobicContact CZ3-CD2 4.42Å; W253-L256 PolarHBondContact O-N 3.31Å; W253-R257 HydrophobicContact CD2-CB 4.49Å; W253-R257 HydrophobicContact CH2-CB 4.31Å; W253-R257 HydrophobicContact CZ2-CB 4.2Å; W253-R257 WeakPolarHBondContact O-CG 3.5Å; W253-R257 PolarHBondContact O-N 3.34Å; W253-M284 HydrophobicContact CB-CG 3.94Å; W253-M284 HydrophobicContact CB-SD 3.99Å; W253-M284 HydrophobicContact CE3-SD 4.46Å; W253-L288 HydrophobicContact CD2-CD1 4.26Å; W253-L288 HydrophobicContact CD2-CD2 3.52Å; W253-L288 HydrophobicContact CD2-CG 4.38Å; W253-L288 VanDerWaalsContact CE2-CD2 3.41Å; W253-L288 HydrophobicContact CE3-CD1 3.71Å; W253-L288 HydrophobicContact CE3-CD2 3.76Å; W253-L288 HydrophobicContact CE3-CG 4.32Å; W253-L288 HydrophobicContact CG-CD2 4.12Å; W253-L288 HydrophobicContact CH2-CD1 4.46Å; W253-L288 HydrophobicContact CH2-CD2 3.82Å; W253-L288 HydrophobicContact CZ2-CD2 3.56Å; W253-L288 HydrophobicContact CZ3-CD1 3.84Å; W253-L288 HydrophobicContact CZ3-CD2 3.91Å; W253-V299 HydrophobicContact CZ2-CG1 4.44Å; W253-D302 HydrophobicContact CH2-CB 3.86Å; W253-D302 HydrophobicContact CZ2-CB 3.54Å; W253-V303 HydrophobicContact CH2-CB 4.47Å; W253-V303 HydrophobicContact CH2-CG2 3.66Å; W253-V303 HydrophobicContact CZ2-CG2 4.2Å; W253-V303 HydrophobicContact CZ3-CG2 4.34Å; W253-V306 HydrophobicContact CZ3-CG2 4.49Å
254D98.7Very high98.1Very high11 Ų1120.1 Ų20.16%0.05911%0.109CC..Hα-helixtrans-61.2-41.9176.6-79.4-21.7000112.2G147 C148 C250 W251 R257 R258G147-D254 WeakPolarHBondContact CA-OD2 3.4Å; C148-D254 HydrophobicContact CB-CB 3.67Å; C148-D254 PolarHBondContact N-OD2 3.49Å; C250-D254 PolarHBondContact O-N 3.2Å; W251-D254 PolarHBondContact O-N 3.46Å; D254-R257 IonicContact OD1-CZ 3.27Å; D254-R257 IonicContact OD1-NE 3.73Å; D254-R257 PolarHBondContact OD1-NE 3.12Å; D254-R257 IonicContact OD1-NH2 3.88Å; D254-R257 PolarHBondContact OD1-NH2 3.49Å; D254-R258 WeakPolarHBondContact O-CB 3.28Å; D254-R258 WeakPolarHBondContact O-CG 3.3Å; D254-R258 PolarHBondContact O-N 3.31Å; D254-R258 VanDerWaalsContact O-N 3.08Å; D254-R258 IonicContact OD1-NH2 3.5Å; D254-R258 IonicContact OD2-NH2 2.99Å
255Y98.3Very high98.1Very high48 Ų4820 Ų2019%0.18811%0.108CC..Hα-helixtrans-59.7-48.7173.6-101.8-90.6000112.1C148 D151 W251 L252 W253 S259 I448C148-Y255 WeakPolarHBondContact SG-CE2 3.38Å; D151-Y255 WeakPolarHBondContact O-CE2 3.42Å; D151-Y255 PolarHBondContact O-OH 3.12Å; W251-Y255 AromaticContact CD2-CD2 3.88Å; W251-Y255 HydrophobicContact CD2-CD2 3.88Å; W251-Y255 HydrophobicContact CD2-CE2 4.05Å; W251-Y255 AromaticContact CE2-CD2 3.51Å; W251-Y255 AromaticContact CE2-CE2 3.19Å; W251-Y255 HydrophobicContact CE3-CD2 4.42Å; W251-Y255 HydrophobicContact CG-CD2 4.31Å; W251-Y255 HydrophobicContact CH2-CD2 4.33Å; W251-Y255 HydrophobicContact CH2-CE2 4.09Å; W251-Y255 AromaticContact CZ2-CD2 3.75Å; W251-Y255 HydrophobicContact CZ2-CD2 3.75Å; W251-Y255 AromaticContact CZ2-CE2 3.21Å; W251-Y255 HydrophobicContact CZ2-CE2 3.21Å; W251-Y255 AromaticContact CZ2-CZ 3.73Å; W251-Y255 AromaticContact NE1-CD2 3.74Å; W251-Y255 AromaticContact NE1-CE2 3.28Å; W251-Y255 VanDerWaalsContact NE1-CE2 3.28Å; W251-Y255 PolarHBondContact O-N 3.2Å; L252-Y255 PolarHBondContact O-N 2.88Å; W253-Y255 VanDerWaalsContact C-N 3.33Å; W253-Y255 PolarHBondContact O-N 3.27Å; Y255-S259 WeakPolarHBondContact O-CB 3.49Å; Y255-S259 PolarHBondContact O-N 3.38Å; Y255-S259 PolarHBondContact O-OG 3.01Å; Y255-I448 HydrophobicContact CD1-CD1 3.98Å; Y255-I448 HydrophobicContact CD1-CG2 3.91Å; Y255-I448 HydrophobicContact CE1-CG2 3.63Å; Y255-I448 HydrophobicContact CG-CD1 3.97Å
256L98.4Very high98.1Very high0 Ų019.8 Ų19.80%011%0.107CC..Hα-helixtrans-63.7-53.5-177.3-178.757000111.1L252 W253 R258 S259 Q261 F264 V306 L324L252-L256 WeakPolarHBondContact O-CB 3.34Å; L252-L256 PolarHBondContact O-N 2.94Å; W253-L256 HydrophobicContact CE3-CD2 4.48Å; W253-L256 HydrophobicContact CZ3-CD2 4.42Å; W253-L256 PolarHBondContact O-N 3.31Å; L256-R258 VanDerWaalsContact C-N 3.26Å; L256-R258 PolarHBondContact O-N 3.05Å; L256-S259 PolarHBondContact O-N 3.4Å; L256-S259 PolarHBondContact O-OG 2.92Å; L256-S259 VanDerWaalsContact O-OG 3.06Å; L256-Q261 HydrophobicContact CD1-CB 4.27Å; L256-F264 HydrophobicContact CB-CE1 4.46Å; L256-F264 HydrophobicContact CB-CE2 4.11Å; L256-F264 HydrophobicContact CB-CZ 3.69Å; L256-F264 HydrophobicContact CD1-CZ 4.4Å; L256-F264 HydrophobicContact CD2-CD2 4.27Å; L256-F264 HydrophobicContact CD2-CE2 3.67Å; L256-F264 HydrophobicContact CD2-CZ 4.12Å; L256-F264 HydrophobicContact CG-CE2 4.33Å; L256-F264 HydrophobicContact CG-CZ 4.29Å; L256-V306 HydrophobicContact CD1-CG1 4.1Å; L256-V306 HydrophobicContact CD2-CG1 3.81Å; L256-V306 HydrophobicContact CG-CG1 3.87Å; L256-V306 HydrophobicContact CG-CG2 4.41Å; L256-L324 HydrophobicContact CD2-CD1 4.43Å; L256-L324 HydrophobicContact CD2-CD2 4.36Å
257R97.3Very high98.1Very high22 Ų2219.3 Ų19.38%0.08311%0.106CC..Hα-helixtrans-64.1-33.3-176.380.3-172.5174.2109.1-8111.3D178 W253 D254 D302 R305D178-R257 IonicContact OD1-CZ 3.78Å; D178-R257 IonicContact OD1-NH1 3.03Å; D178-R257 PolarHBondContact OD1-NH1 3.03Å; D178-R257 IonicContact OD1-NH2 3.85Å; D178-R257 PolarHBondContact OD1-NH2 3.37Å; D178-R257 IonicContact OD2-NH1 3.51Å; D178-R257 PolarHBondContact OD2-NH1 3.4Å; W253-R257 HydrophobicContact CD2-CB 4.49Å; W253-R257 HydrophobicContact CH2-CB 4.31Å; W253-R257 HydrophobicContact CZ2-CB 4.2Å; W253-R257 WeakPolarHBondContact O-CG 3.5Å; W253-R257 PolarHBondContact O-N 3.34Å; D254-R257 IonicContact OD1-CZ 3.27Å; D254-R257 IonicContact OD1-NE 3.73Å; D254-R257 PolarHBondContact OD1-NE 3.12Å; D254-R257 IonicContact OD1-NH2 3.88Å; D254-R257 PolarHBondContact OD1-NH2 3.49Å; R257-D302 HydrophobicContact CB-CB 4.39Å; R257-D302 IonicContact NH1-OD2 3.56Å; R257-R305 VanDerWaalsContact O-CZ 3.26Å; R257-R305 PolarHBondContact O-NH1 3.34Å; R257-R305 PolarHBondContact O-NH2 3.18Å
258R97.8Very high98Very high127 Ų12719.4 Ų19.448%0.47911%0.106SC..Hα-helixtrans-90.1-23.3-176.7-61176.6-173.5-177.111.9114.4C148 D254 L256 G260C148-R258 PolarHBondContact O-NH1 3.38Å; C148-R258 PolarHBondContact O-NH2 3.03Å; D254-R258 WeakPolarHBondContact O-CB 3.28Å; D254-R258 WeakPolarHBondContact O-CG 3.3Å; D254-R258 PolarHBondContact O-N 3.31Å; D254-R258 VanDerWaalsContact O-N 3.08Å; D254-R258 IonicContact OD1-NH2 3.5Å; D254-R258 IonicContact OD2-NH2 2.99Å; L256-R258 VanDerWaalsContact C-N 3.26Å; L256-R258 PolarHBondContact O-N 3.05Å; R258-G260 VanDerWaalsContact C-N 3.3Å; R258-G260 PolarHBondContact O-N 3.39Å
259S96.9Very high97.9Very high48 Ų4822.4 Ų22.434%0.33613%0.128SC..Hα-helixtrans-74.6-18179.362.20000114.2Y255 L256 Q261Y255-S259 WeakPolarHBondContact O-CB 3.49Å; Y255-S259 PolarHBondContact O-N 3.38Å; Y255-S259 PolarHBondContact O-OG 3.01Å; L256-S259 PolarHBondContact O-N 3.4Å; L256-S259 PolarHBondContact O-OG 2.92Å; L256-S259 VanDerWaalsContact O-OG 3.06Å; S259-Q261 PolarHBondContact O-N 2.88Å; S259-Q261 WeakPolarHBondContact OG-CG 3.37Å; S259-Q261 PolarHBondContact OG-N 2.84Å
260G94.4Very high97.6Very high53 Ų5322.5 Ų22.555%0.54613%0.128SC..THydrogen-bonded Turntrans74.811.7-173.900000114.1R258R258-G260 VanDerWaalsContact C-N 3.3Å; R258-G260 PolarHBondContact O-N 3.39Å
261Q96.8Very high97.5Very high64 Ų6423.6 Ų23.630%0.29914%0.14SC..  trans-81.6158.8177.2-61.9-59.6-40.200112L256 S259 G421 L423L256-Q261 HydrophobicContact CD1-CB 4.27Å; S259-Q261 PolarHBondContact O-N 2.88Å; S259-Q261 WeakPolarHBondContact OG-CG 3.37Å; S259-Q261 PolarHBondContact OG-N 2.84Å; Q261-G421 PolarHBondContact OE1-O 3.2Å; Q261-L423 HydrophobicContact CB-CD1 4.41Å; Q261-L423 HydrophobicContact CB-CG 3.97Å; Q261-L423 HydrophobicContact CG-CD1 4.37Å; Q261-L423 HydrophobicContact CG-CD2 3.76Å; Q261-L423 HydrophobicContact CG-CG 3.74Å
262G95.8Very high97.3Very high7 Ų724.6 Ų24.67%0.07215%0.146CC..  trans-93.72-175.600000114.6G421G262-G421 PolarHBondContact N-O 3.26Å
263G98.3Very high97.3Very high0 Ų025.3 Ų25.30%015%0.15CC..  trans156.1-158.6178.900000113.6L324 L422 L423G263-L324 CarbonylContact C-O 3.2Å; G263-L324 WeakPolarHBondContact CA-O 3.31Å; G263-L422 WeakPolarHBondContact O-CA 3.32Å; G263-L423 PolarHBondContact O-N 3.06Å
264F98.8Very high97.2Very high0 Ų025.4 Ų25.40%015%0.151CC..EExtended strand (participates in β ladder)trans-122.7148.3-178.9-62.8-67.1000112.3L252 L256 V281 M284 L324 F325 T326 L423 L425 I448L252-F264 HydrophobicContact CB-CE2 4.4Å; L252-F264 HydrophobicContact CB-CZ 3.97Å; L252-F264 HydrophobicContact CD2-CE1 4.17Å; L252-F264 HydrophobicContact CD2-CZ 4.14Å; L252-F264 HydrophobicContact CG-CZ 4.49Å; L256-F264 HydrophobicContact CB-CE1 4.46Å; L256-F264 HydrophobicContact CB-CE2 4.11Å; L256-F264 HydrophobicContact CB-CZ 3.69Å; L256-F264 HydrophobicContact CD1-CZ 4.4Å; L256-F264 HydrophobicContact CD2-CD2 4.27Å; L256-F264 HydrophobicContact CD2-CE2 3.67Å; L256-F264 HydrophobicContact CD2-CZ 4.12Å; L256-F264 HydrophobicContact CG-CE2 4.33Å; L256-F264 HydrophobicContact CG-CZ 4.29Å; F264-V281 HydrophobicContact CD2-CG1 4.36Å; F264-M284 HydrophobicContact CD2-CE 4.47Å; F264-M284 HydrophobicContact CE2-CE 3.89Å; F264-M284 HydrophobicContact CE2-SD 4Å; F264-L324 PolarHBondContact N-O 3.49Å; F264-F325 HydrophobicContact CB-CD2 3.8Å; F264-F325 HydrophobicContact CB-CE2 4.2Å; F264-T326 PolarHBondContact O-N 2.96Å; F264-L423 CarbonylContact C-O 3.57Å; F264-L423 WeakPolarHBondContact CA-O 3.36Å; F264-L423 HydrophobicContact CD1-CB 3.77Å; F264-L423 HydrophobicContact CD1-CD1 4.36Å; F264-L423 HydrophobicContact CE1-CB 4.07Å; F264-L423 HydrophobicContact CE1-CD1 3.82Å; F264-L425 HydrophobicContact CB-CD1 3.86Å; F264-L425 HydrophobicContact CB-CG 4.1Å; F264-L425 HydrophobicContact CD1-CD1 3.99Å; F264-L425 HydrophobicContact CD1-CD2 3.56Å; F264-L425 HydrophobicContact CD1-CG 3.84Å; F264-L425 HydrophobicContact CE1-CD2 3.91Å; F264-L425 HydrophobicContact CG-CD1 3.93Å; F264-L425 HydrophobicContact CG-CD2 4.34Å; F264-L425 HydrophobicContact CG-CG 4.2Å; F264-I448 HydrophobicContact CE1-CD1 4.26Å
265L98.8Very high97.2Very high0 Ų024.9 Ų24.90%015%0.148CC..EExtended strand (participates in β ladder)trans-116.8128.4163.8-176.3144.4000109.8P267 T326 A405 F408 A409 L422 L423 V424 L425L265-P267 HydrophobicContact CD2-CG 4.29Å; L265-T326 CarbonylContact C-O 3.49Å; L265-T326 VanDerWaalsContact CA-O 3.27Å; L265-T326 WeakPolarHBondContact CA-O 3.3Å; L265-A405 HydrophobicContact CD2-CB 3.93Å; L265-F408 HydrophobicContact CD1-CB 3.43Å; L265-F408 VanDerWaalsContact CD1-CB 3.43Å; L265-A409 HydrophobicContact CB-CB 4.06Å; L265-A409 HydrophobicContact CD1-CB 4.12Å; L265-L422 HydrophobicContact CB-CB 4.02Å; L265-L422 HydrophobicContact CB-CD1 4.03Å; L265-L422 HydrophobicContact CD1-CD1 4.45Å; L265-L423 PolarHBondContact N-O 3.25Å; L265-V424 HydrophobicContact CD2-CG1 4.41Å; L265-V424 CarbonylContact O-C 3.57Å; L265-V424 WeakPolarHBondContact O-CA 3.46Å; L265-L425 PolarHBondContact O-N 3.06Å
266L98.8Very high97.2Very high0 Ų022.6 Ų22.60%014%0.139CC..EExtended strand (participates in β ladder)trans-121.4122.8173.8174.467.6000111.2L268 S274 T277 A278 F325 T326 T327 C328 L425 S427L266-L268 HydrophobicContact CD2-CD1 4.06Å; L266-L268 PolarHBondContact O-N 3.49Å; L266-S274 WeakPolarHBondContact CD2-O 3.47Å; L266-T277 HydrophobicContact CD1-CG2 3.74Å; L266-T277 HydrophobicContact CD2-CG2 4.06Å; L266-T277 HydrophobicContact CG-CG2 4.49Å; L266-A278 HydrophobicContact CD2-CB 3.95Å; L266-F325 HydrophobicContact CB-CE2 3.44Å; L266-F325 VanDerWaalsContact CB-CE2 3.44Å; L266-F325 HydrophobicContact CB-CZ 3.6Å; L266-F325 HydrophobicContact CD2-CE2 4.35Å; L266-F325 HydrophobicContact CD2-CZ 3.64Å; L266-F325 HydrophobicContact CG-CZ 4.26Å; L266-T326 PolarHBondContact N-O 3.09Å; L266-T327 CarbonylContact O-C 3.52Å; L266-T327 WeakPolarHBondContact O-CA 3.1Å; L266-C328 PolarHBondContact O-N 3.16Å; L266-L425 HydrophobicContact CB-CB 4.46Å; L266-L425 HydrophobicContact CD1-CB 4.03Å; L266-S427 WeakPolarHBondContact CD1-OG 3.3Å
267P98.4Very high97.3Very high21 Ų2122.6 Ų22.614%0.13614%0.139CC..EExtended strand (participates in β ladder)trans-64.9100.6161.7-20.235.2000110.2L265 C328 M330 A405 C443L265-P267 HydrophobicContact CD2-CG 4.29Å; P267-C328 CarbonylContact C-O 3.5Å; P267-C328 WeakPolarHBondContact CA-O 3.42Å; P267-M330 HydrophobicContact CB-CE 4.07Å; P267-M330 HydrophobicContact CG-CE 4.19Å; P267-A405 HydrophobicContact CG-CB 3.84Å; P267-C443 HydrophobicContact CB-CB 4.32Å; P267-C443 HydrophobicContact CG-CB 4.2Å
268L98.1Very high97.3Very high2 Ų221.5 Ų21.51%0.0114%0.135CC..  trans-95.5111.4-174.2-174.165000109.8L266 A278 T327 C328 Y329 A343 L346 A347L266-L268 HydrophobicContact CD2-CD1 4.06Å; L266-L268 PolarHBondContact O-N 3.49Å; L268-A278 HydrophobicContact CD1-CB 4.28Å; L268-T327 HydrophobicContact CB-CG2 4.47Å; L268-T327 HydrophobicContact CD2-CG2 4.1Å; L268-C328 PolarHBondContact N-O 3.11Å; L268-Y329 WeakPolarHBondContact O-CA 3.39Å; L268-Y329 WeakPolarHBondContact O-CD2 3.35Å; L268-A343 HydrophobicContact CD2-CB 4.12Å; L268-A343 VanDerWaalsContact CD2-O 3.3Å; L268-A343 WeakPolarHBondContact CD2-O 3.35Å; L268-A343 HydrophobicContact CG-CB 4.05Å; L268-L346 HydrophobicContact CD1-CD2 4.48Å; L268-A347 HydrophobicContact CD2-CB 4.14Å
269S95.5Very high97.4Very high65 Ų6515.5 Ų15.546%0.45511%0.112SC..  trans-91.2-13.8-174.2620000114.7G271 S274S269-G271 PolarHBondContact OG-N 3.01Å; S269-S274 PolarHBondContact N-OG 3.36Å; S269-S274 PolarHBondContact OG-OG 3.35Å
270G93.8Very high97.5Very high1 Ų113.2 Ų13.21%0.0110%0.096CC..SBendtrans75.414.2-170.700000113.8R342G270-R342 PolarHBondContact O-NE 3.19Å; G270-R342 VanDerWaalsContact O-NE 3.09Å
271G94.9Very high97.7Very high26 Ų2610.7 Ų10.727%0.2687%0.07SC..SBendtrans-101.5174.7169.700000112.4S269 D273 S275S269-G271 PolarHBondContact OG-N 3.01Å; G271-D273 PolarHBondContact O-N 2.98Å; G271-S275 VanDerWaalsContact O-CB 3.25Å; G271-S275 WeakPolarHBondContact O-CB 3.44Å; G271-S275 PolarHBondContact O-N 2.75Å; G271-S275 PolarHBondContact O-OG 2.79Å
272V96.4Very high97.8Very high21 Ų218.1 Ų8.113%0.1276%0.058CC..Hα-helixtrans-54.8-52.5-174.5170.70000112.2S275 S276 L459 K460 L463 I478V272-S275 CarbonylContact O-C 3.58Å; V272-S275 WeakPolarHBondContact O-CB 3.4Å; V272-S275 PolarHBondContact O-N 3.27Å; V272-S276 PolarHBondContact O-N 3.41Å; V272-S276 PolarHBondContact O-OG 3.24Å; V272-S276 VanDerWaalsContact O-OG 3.08Å; V272-L459 HydrophobicContact CG1-CB 4.23Å; V272-K460 HydrophobicContact CG1-CG 4.1Å; V272-K460 HydrophobicContact CG2-CG 4.48Å; V272-L463 HydrophobicContact CB-CD1 4.24Å; V272-L463 HydrophobicContact CG1-CD1 3.85Å; V272-L463 HydrophobicContact CG2-CD1 4.42Å; V272-I478 HydrophobicContact CG2-CG2 4.39Å
273D97.3Very high97.9Very high14 Ų148 Ų88%0.0756%0.056CC..Hα-helixtrans-71.6-43.9-165.5-55.5-3.3000113.6G271 S275 S276 T277 S427 N429 I451 K456G271-D273 PolarHBondContact O-N 2.98Å; D273-S275 VanDerWaalsContact C-N 3.27Å; D273-S275 PolarHBondContact O-N 2.93Å; D273-S276 PolarHBondContact O-N 2.9Å; D273-T277 PolarHBondContact O-N 3.25Å; D273-T277 PolarHBondContact O-OG1 3.32Å; D273-T277 VanDerWaalsContact O-OG1 3.13Å; D273-S427 WeakPolarHBondContact CB-O 3.41Å; D273-N429 PolarHBondContact OD2-ND2 3.44Å; D273-I451 HydrophobicContact CB-CD1 3.76Å; D273-I451 VanDerWaalsContact O-CD1 3.25Å; D273-I451 WeakPolarHBondContact O-CD1 3.49Å; D273-K456 WeakPolarHBondContact OD1-CD 3.48Å; D273-K456 WeakPolarHBondContact OD1-CE 3.39Å; D273-K456 IonicContact OD1-NZ 2.85Å; D273-K456 PolarHBondContact OD1-NZ 2.86Å; D273-K456 IonicContact OD2-NZ 2.82Å; D273-K456 PolarHBondContact OD2-NZ 2.8Å
274S98Very high97.9Very high3 Ų38 Ų82%0.0216%0.056CC..Hα-helixtrans-66-35.1174.762.10000111L266 S269 T277 A278 S427L266-S274 WeakPolarHBondContact CD2-O 3.47Å; S269-S274 PolarHBondContact N-OG 3.36Å; S269-S274 PolarHBondContact OG-OG 3.35Å; S274-T277 WeakPolarHBondContact O-CB 3.3Å; S274-T277 PolarHBondContact O-N 3.35Å; S274-A278 PolarHBondContact O-N 3.31Å; S274-S427 WeakPolarHBondContact CA-OG 3.49Å
275S98.6Very high97.9Very high0 Ų08 Ų80%06%0.056CC..Hα-helixtrans-65.2-39.1173-55.30000112.1G271 V272 D273 T277 A278 C279 L346 I478G271-S275 VanDerWaalsContact O-CB 3.25Å; G271-S275 WeakPolarHBondContact O-CB 3.44Å; G271-S275 PolarHBondContact O-N 2.75Å; G271-S275 PolarHBondContact O-OG 2.79Å; V272-S275 CarbonylContact O-C 3.58Å; V272-S275 WeakPolarHBondContact O-CB 3.4Å; V272-S275 PolarHBondContact O-N 3.27Å; D273-S275 VanDerWaalsContact C-N 3.27Å; D273-S275 PolarHBondContact O-N 2.93Å; S275-T277 VanDerWaalsContact C-N 3.33Å; S275-T277 PolarHBondContact O-N 3.04Å; S275-A278 WeakPolarHBondContact O-CB 3.19Å; S275-A278 PolarHBondContact O-N 2.91Å; S275-C279 PolarHBondContact O-N 2.82Å; S275-C279 PolarHBondContact O-SG 2.98Å; S275-L346 WeakPolarHBondContact OG-CD2 3.42Å; S275-I478 WeakPolarHBondContact OG-CD1 3.14Å
276S98.7Very high97.9Very high0 Ų010.1 Ų10.10%07%0.069CC..Hα-helixtrans-63-41.1174.5-58.20000111.6V272 D273 A278 C279 I280 L463V272-S276 PolarHBondContact O-N 3.41Å; V272-S276 PolarHBondContact O-OG 3.24Å; V272-S276 VanDerWaalsContact O-OG 3.08Å; D273-S276 PolarHBondContact O-N 2.9Å; S276-A278 VanDerWaalsContact C-N 3.32Å; S276-A278 PolarHBondContact O-N 2.96Å; S276-C279 PolarHBondContact O-N 3.34Å; S276-I280 WeakPolarHBondContact O-CG1 3.44Å; S276-I280 PolarHBondContact O-N 2.98Å; S276-L463 WeakPolarHBondContact OG-CG 3.42Å
277T98.9Very high97.9Very high0 Ų012.1 Ų12.10%08%0.079CC..Hα-helixtrans-60.8-43.2174.3-55.90000111.1L266 D273 S274 S275 I280 V281 L425 S427 P450L266-T277 HydrophobicContact CD1-CG2 3.74Å; L266-T277 HydrophobicContact CD2-CG2 4.06Å; L266-T277 HydrophobicContact CG-CG2 4.49Å; D273-T277 PolarHBondContact O-N 3.25Å; D273-T277 PolarHBondContact O-OG1 3.32Å; D273-T277 VanDerWaalsContact O-OG1 3.13Å; S274-T277 WeakPolarHBondContact O-CB 3.3Å; S274-T277 PolarHBondContact O-N 3.35Å; S275-T277 VanDerWaalsContact C-N 3.33Å; S275-T277 PolarHBondContact O-N 3.04Å; T277-I280 PolarHBondContact O-N 3.44Å; T277-V281 PolarHBondContact O-N 3.03Å; T277-V281 VanDerWaalsContact O-N 3.17Å; T277-L425 HydrophobicContact CG2-CB 4.03Å; T277-L425 HydrophobicContact CG2-CD1 3.95Å; T277-S427 PolarHBondContact OG1-OG 3.37Å; T277-P450 HydrophobicContact CG2-CG 3.69Å
278A98.8Very high98Very high0 Ų011.1 Ų11.10%07%0.073CC..Hα-helixtrans-63.3-41.1175.800000112.7L266 L268 S274 S275 S276 I280 V281 H282 F325 L346 I350L266-A278 HydrophobicContact CD2-CB 3.95Å; L268-A278 HydrophobicContact CD1-CB 4.28Å; S274-A278 PolarHBondContact O-N 3.31Å; S275-A278 WeakPolarHBondContact O-CB 3.19Å; S275-A278 PolarHBondContact O-N 2.91Å; S276-A278 VanDerWaalsContact C-N 3.32Å; S276-A278 PolarHBondContact O-N 2.96Å; A278-I280 VanDerWaalsContact C-N 3.33Å; A278-I280 PolarHBondContact O-N 2.67Å; A278-V281 PolarHBondContact O-N 3.12Å; A278-H282 PolarHBondContact O-N 3.39Å; A278-F325 HydrophobicContact CB-CE1 4.04Å; A278-F325 HydrophobicContact CB-CZ 4.29Å; A278-L346 HydrophobicContact CB-CD2 4.31Å; A278-I350 HydrophobicContact CB-CD1 3.88Å
279C98.8Very high98Very high0 Ų011.5 Ų11.50%08%0.076CC..Hα-helixtrans-63.8-35.7175.4-69.20000112.7S275 S276 H282 S283 F462 L463 C466S275-C279 PolarHBondContact O-N 2.82Å; S275-C279 PolarHBondContact O-SG 2.98Å; S276-C279 PolarHBondContact O-N 3.34Å; C279-H282 PolarHBondContact O-N 2.84Å; C279-S283 WeakPolarHBondContact O-CB 3.39Å; C279-S283 PolarHBondContact O-N 2.96Å; C279-F462 HydrophobicContact CB-CE1 3.82Å; C279-F462 HydrophobicContact CB-CZ 3.84Å; C279-L463 HydrophobicContact CB-CD2 4.36Å; C279-C466 HydrophobicContact CB-CB 4.33Å
280I98.9Very high98.1Very high0 Ų012.6 Ų12.60%07%0.074CC..Hα-helixtrans-65.4-43174.5-69.1165.1000110.7P248 A249 L252 S276 T277 A278 H282 S283 M284 P450 I451 F462P248-I280 HydrophobicContact CB-CD1 3.88Å; P248-I280 HydrophobicContact CB-CG1 4.33Å; P248-I280 HydrophobicContact CB-CG2 3.73Å; P248-I280 HydrophobicContact CG-CD1 4.38Å; A249-I280 HydrophobicContact CB-CG2 4.18Å; L252-I280 HydrophobicContact CD1-CG2 3.74Å; L252-I280 HydrophobicContact CG-CG2 4.5Å; S276-I280 WeakPolarHBondContact O-CG1 3.44Å; S276-I280 PolarHBondContact O-N 2.98Å; T277-I280 PolarHBondContact O-N 3.44Å; A278-I280 VanDerWaalsContact C-N 3.33Å; A278-I280 PolarHBondContact O-N 2.67Å; I280-H282 VanDerWaalsContact C-N 3.31Å; I280-H282 PolarHBondContact O-N 2.99Å; I280-S283 WeakPolarHBondContact O-CB 3.5Å; I280-S283 PolarHBondContact O-N 3.47Å; I280-M284 PolarHBondContact O-N 2.62Å; I280-P450 HydrophobicContact CD1-CB 4.3Å; I280-P450 HydrophobicContact CG2-CB 4.4Å; I280-I451 HydrophobicContact CD1-CG2 3.36Å; I280-F462 HydrophobicContact CD1-CE1 4.49Å; I280-F462 HydrophobicContact CG1-CE1 3.95Å; I280-F462 HydrophobicContact CG1-CZ 3.85Å
281V98.9Very high98.3Very high0 Ų013 Ų130%08%0.077CC..Hα-helixtrans-64.7-37.8175.4178.80000111.1L252 F264 T277 A278 M284 C285 F325 L425L252-V281 HydrophobicContact CD1-CG2 3.83Å; F264-V281 HydrophobicContact CD2-CG1 4.36Å; T277-V281 PolarHBondContact O-N 3.03Å; T277-V281 VanDerWaalsContact O-N 3.17Å; A278-V281 PolarHBondContact O-N 3.12Å; V281-M284 HydrophobicContact CG1-CE 4.3Å; V281-M284 WeakPolarHBondContact O-CB 3.4Å; V281-M284 PolarHBondContact O-N 3.48Å; V281-C285 PolarHBondContact O-N 3.27Å; V281-C285 VanDerWaalsContact O-N 3.08Å; V281-C285 PolarHBondContact O-SG 3.06Å; V281-F325 HydrophobicContact CB-CD1 4.09Å; V281-F325 HydrophobicContact CB-CE1 3.99Å; V281-F325 HydrophobicContact CB-CG 4.42Å; V281-F325 HydrophobicContact CB-CZ 4.2Å; V281-F325 HydrophobicContact CG1-CB 3.92Å; V281-F325 HydrophobicContact CG1-CD1 3.64Å; V281-F325 HydrophobicContact CG1-CD2 4.05Å; V281-F325 HydrophobicContact CG1-CE1 4.06Å; V281-F325 HydrophobicContact CG1-CE2 4.41Å; V281-F325 HydrophobicContact CG1-CG 3.63Å; V281-F325 HydrophobicContact CG1-CZ 4.41Å; V281-F325 HydrophobicContact CG2-CE1 4.36Å; V281-F325 HydrophobicContact CG2-CE2 4.15Å; V281-F325 HydrophobicContact CG2-CZ 4.06Å; V281-L425 HydrophobicContact CG2-CD1 3.64Å
282H98.8Very high98.5Very high11 Ų1112.6 Ų12.65%0.0517%0.069CC..Hα-helixtrans-64.5-46174.1-174.269.4000111.8A278 C279 I280 M284 C285 V286 I350 F470A278-H282 PolarHBondContact O-N 3.39Å; C279-H282 PolarHBondContact O-N 2.84Å; I280-H282 VanDerWaalsContact C-N 3.31Å; I280-H282 PolarHBondContact O-N 2.99Å; H282-M284 VanDerWaalsContact C-N 3.29Å; H282-M284 PolarHBondContact O-N 2.91Å; H282-C285 WeakPolarHBondContact O-CA 3.44Å; H282-C285 WeakPolarHBondContact O-CB 3.38Å; H282-C285 PolarHBondContact O-N 2.93Å; H282-V286 WeakPolarHBondContact O-CG2 3.38Å; H282-V286 PolarHBondContact O-N 3.12Å; H282-I350 HydrophobicContact CB-CB 4.18Å; H282-I350 HydrophobicContact CB-CG2 4.03Å; H282-I350 PolarHBondContact ND1-O 3.36Å; H282-F470 AromaticContact CD2-CG 3.98Å
283S98.8Very high98.5Very high3 Ų318.5 Ų18.52%0.02110%0.096CC..Hα-helixtrans-56.2-43.5174-173.40000111.5S245 C279 I280 C285 V286 L287S245-S283 WeakPolarHBondContact O-CB 3.5Å; S245-S283 PolarHBondContact O-OG 3.1Å; C279-S283 WeakPolarHBondContact O-CB 3.39Å; C279-S283 PolarHBondContact O-N 2.96Å; I280-S283 WeakPolarHBondContact O-CB 3.5Å; I280-S283 PolarHBondContact O-N 3.47Å; S283-C285 VanDerWaalsContact C-N 3.31Å; S283-C285 PolarHBondContact O-N 3.43Å; S283-V286 WeakPolarHBondContact O-CB 3.46Å; S283-V286 PolarHBondContact O-N 3.25Å; S283-V286 VanDerWaalsContact O-N 3.13Å; S283-L287 WeakPolarHBondContact O-CG 3.32Å; S283-L287 PolarHBondContact O-N 3.48Å
284M98.9Very high98.5Very high0 Ų023 Ų230%012%0.12CC..Hα-helixtrans-56.7-44173-175.7-163.571.800111.7A249 L252 W253 F264 I280 V281 H282 V286 L287 L288 L324A249-M284 HydrophobicContact CB-CB 3.97Å; A249-M284 WeakPolarHBondContact O-CG 3.33Å; L252-M284 HydrophobicContact CB-SD 3.97Å; W253-M284 HydrophobicContact CB-CG 3.94Å; W253-M284 HydrophobicContact CB-SD 3.99Å; W253-M284 HydrophobicContact CE3-SD 4.46Å; F264-M284 HydrophobicContact CD2-CE 4.47Å; F264-M284 HydrophobicContact CE2-CE 3.89Å; F264-M284 HydrophobicContact CE2-SD 4Å; I280-M284 PolarHBondContact O-N 2.62Å; V281-M284 HydrophobicContact CG1-CE 4.3Å; V281-M284 WeakPolarHBondContact O-CB 3.4Å; V281-M284 PolarHBondContact O-N 3.48Å; H282-M284 VanDerWaalsContact C-N 3.29Å; H282-M284 PolarHBondContact O-N 2.91Å; M284-V286 VanDerWaalsContact C-N 3.35Å; M284-V286 PolarHBondContact O-N 3.39Å; M284-L287 PolarHBondContact O-N 2.83Å; M284-L288 HydrophobicContact CE-CD1 4.2Å; M284-L288 HydrophobicContact CG-CD1 4.14Å; M284-L288 VanDerWaalsContact O-CG 3.22Å; M284-L288 WeakPolarHBondContact O-CG 3.25Å; M284-L288 PolarHBondContact O-N 3.32Å; M284-L324 HydrophobicContact CE-CD1 4.2Å
285C98.8Very high98.4Very high0 Ų027.8 Ų27.80%015%0.153CC..Hα-helixtrans-64.7-38.1176.9-62.20000112.4V281 H282 S283 L288 C289 P317 L320V281-C285 PolarHBondContact O-N 3.27Å; V281-C285 VanDerWaalsContact O-N 3.08Å; V281-C285 PolarHBondContact O-SG 3.06Å; H282-C285 WeakPolarHBondContact O-CA 3.44Å; H282-C285 WeakPolarHBondContact O-CB 3.38Å; H282-C285 PolarHBondContact O-N 2.93Å; S283-C285 VanDerWaalsContact C-N 3.31Å; S283-C285 PolarHBondContact O-N 3.43Å; C285-L288 PolarHBondContact O-N 3.34Å; C285-C289 PolarHBondContact O-N 3.46Å; C285-P317 HydrophobicContact CB-CB 4.23Å; C285-L320 HydrophobicContact CB-CD2 4.05Å; C285-L320 HydrophobicContact CB-CG 4.3Å
286V98.7Very high98.4Very high46 Ų4629.1 Ų29.128%0.27916%0.16SC..Hα-helixtrans-61.2-48.3174.3175.10000110.5H282 S283 M284 L288 C289 Q290 P317 F470H282-V286 WeakPolarHBondContact O-CG2 3.38Å; H282-V286 PolarHBondContact O-N 3.12Å; S283-V286 WeakPolarHBondContact O-CB 3.46Å; S283-V286 PolarHBondContact O-N 3.25Å; S283-V286 VanDerWaalsContact O-N 3.13Å; M284-V286 VanDerWaalsContact C-N 3.35Å; M284-V286 PolarHBondContact O-N 3.39Å; V286-L288 VanDerWaalsContact C-N 3.29Å; V286-L288 PolarHBondContact O-N 2.69Å; V286-C289 PolarHBondContact O-N 2.72Å; V286-Q290 PolarHBondContact O-N 2.94Å; V286-P317 HydrophobicContact CB-CG 4.39Å; V286-P317 HydrophobicContact CG2-CB 3.8Å; V286-P317 HydrophobicContact CG2-CG 3.86Å; V286-F470 HydrophobicContact CG2-CD1 4.35Å; V286-F470 HydrophobicContact CG2-CE1 4.17Å
287L98.7Very high98.3Very high41 Ų4133.7 Ų33.722%0.21519%0.192CC..Hα-helixtrans-61.3-37.5177.8-67.1173.1000112.4L176 L246 A249 S283 M284 Q290 A291L176-L287 HydrophobicContact CD1-CB 3.95Å; L176-L287 HydrophobicContact CG-CB 4.39Å; L246-L287 HydrophobicContact CD2-CD1 4.02Å; L246-L287 HydrophobicContact CD2-CD2 3.77Å; L246-L287 HydrophobicContact CD2-CG 4.4Å; A249-L287 HydrophobicContact CB-CD1 4.04Å; S283-L287 WeakPolarHBondContact O-CG 3.32Å; S283-L287 PolarHBondContact O-N 3.48Å; M284-L287 PolarHBondContact O-N 2.83Å; L287-Q290 PolarHBondContact O-N 3.01Å; L287-A291 WeakPolarHBondContact O-CB 3.45Å; L287-A291 PolarHBondContact O-N 2.72Å
288L98.8Very high98.2Very high0 Ų037.2 Ų37.20%021%0.209CC..Hα-helixtrans-67-43.8177.2-71.7167.5000112.2L176 W253 M284 C285 V286 A291 V292 V299 V303 L320 L324L176-L288 HydrophobicContact CD1-CD2 3.62Å; L176-L288 HydrophobicContact CD1-CG 4.05Å; W253-L288 HydrophobicContact CD2-CD1 4.26Å; W253-L288 HydrophobicContact CD2-CD2 3.52Å; W253-L288 HydrophobicContact CD2-CG 4.38Å; W253-L288 VanDerWaalsContact CE2-CD2 3.41Å; W253-L288 HydrophobicContact CE3-CD1 3.71Å; W253-L288 HydrophobicContact CE3-CD2 3.76Å; W253-L288 HydrophobicContact CE3-CG 4.32Å; W253-L288 HydrophobicContact CG-CD2 4.12Å; W253-L288 HydrophobicContact CH2-CD1 4.46Å; W253-L288 HydrophobicContact CH2-CD2 3.82Å; W253-L288 HydrophobicContact CZ2-CD2 3.56Å; W253-L288 HydrophobicContact CZ3-CD1 3.84Å; W253-L288 HydrophobicContact CZ3-CD2 3.91Å; M284-L288 HydrophobicContact CE-CD1 4.2Å; M284-L288 HydrophobicContact CG-CD1 4.14Å; M284-L288 VanDerWaalsContact O-CG 3.22Å; M284-L288 WeakPolarHBondContact O-CG 3.25Å; M284-L288 PolarHBondContact O-N 3.32Å; C285-L288 PolarHBondContact O-N 3.34Å; V286-L288 VanDerWaalsContact C-N 3.29Å; V286-L288 PolarHBondContact O-N 2.69Å; L288-A291 PolarHBondContact O-N 3.38Å; L288-V292 WeakPolarHBondContact O-CG2 3.47Å; L288-V292 PolarHBondContact O-N 3.42Å; L288-V292 VanDerWaalsContact O-N 3.1Å; L288-V299 HydrophobicContact CD2-CG1 3.56Å; L288-V303 HydrophobicContact CB-CG2 4.46Å; L288-V303 HydrophobicContact CD1-CG2 4.43Å; L288-V303 HydrophobicContact CD2-CG2 3.91Å; L288-L320 HydrophobicContact CB-CD2 3.65Å; L288-L320 HydrophobicContact CD1-CD2 3.92Å; L288-L320 HydrophobicContact CG-CD2 4.44Å; L288-L324 HydrophobicContact CD1-CD1 4.28Å
289C98.6Very high98.2Very high10 Ų1037.3 Ų37.37%0.06821%0.209CC..Hα-helixtrans-60.6-47.6174-74.40000111C285 V286 A291 V292 E293 P317C285-C289 PolarHBondContact O-N 3.46Å; V286-C289 PolarHBondContact O-N 2.72Å; C289-A291 PolarHBondContact O-N 2.74Å; C289-V292 PolarHBondContact O-N 3.36Å; C289-E293 PolarHBondContact O-N 3.42Å; C289-P317 HydrophobicContact CB-CG 4.21Å
290Q98.3Very high98.2Very high88 Ų8839 Ų3941%0.41122%0.218SC..Hα-helixtrans-60-46.8178.5-173.662.256.300111.7V286 L287 V292 E293 D294V286-Q290 PolarHBondContact O-N 2.94Å; L287-Q290 PolarHBondContact O-N 3.01Å; Q290-V292 VanDerWaalsContact C-N 3.27Å; Q290-V292 PolarHBondContact O-N 2.87Å; Q290-E293 WeakPolarHBondContact O-CB 3.25Å; Q290-E293 PolarHBondContact O-N 3.19Å; Q290-E293 VanDerWaalsContact O-N 3.13Å; Q290-D294 PolarHBondContact NE2-OD1 2.92Å; Q290-D294 PolarHBondContact NE2-OD2 2.81Å; Q290-D294 WeakPolarHBondContact O-CB 3.41Å; Q290-D294 PolarHBondContact O-N 2.98Å
291A98.2Very high98.1Very high9 Ų945.8 Ų45.87%0.07425%0.247CC..Hα-helixtrans-62.3-34.8179.100000112.6L176 L287 L288 C289 D294 S295 N296 V299L176-A291 HydrophobicContact CD1-CB 4.07Å; L287-A291 WeakPolarHBondContact O-CB 3.45Å; L287-A291 PolarHBondContact O-N 2.72Å; L288-A291 PolarHBondContact O-N 3.38Å; C289-A291 PolarHBondContact O-N 2.74Å; A291-D294 CarbonylContact O-C 3.57Å; A291-S295 PolarHBondContact O-N 3.39Å; A291-N296 HydrophobicContact CB-CB 4.23Å; A291-N296 WeakPolarHBondContact O-CB 3.31Å; A291-N296 PolarHBondContact O-N 3.49Å; A291-V299 HydrophobicContact CB-CB 4.32Å; A291-V299 HydrophobicContact CB-CG1 4.07Å; A291-V299 HydrophobicContact CB-CG2 4.19Å
292V97.8Very high98.1Very high18 Ų1846.5 Ų46.511%0.10925%0.251CS..Hα-helixtrans-71-39174.7170.80000111.5L288 C289 Q290 D294 S295 V299 L300 T313 P314L288-V292 WeakPolarHBondContact O-CG2 3.47Å; L288-V292 PolarHBondContact O-N 3.42Å; L288-V292 VanDerWaalsContact O-N 3.1Å; C289-V292 PolarHBondContact O-N 3.36Å; Q290-V292 VanDerWaalsContact C-N 3.27Å; Q290-V292 PolarHBondContact O-N 2.87Å; V292-D294 VanDerWaalsContact C-N 3.31Å; V292-S295 WeakPolarHBondContact O-CA 3.4Å; V292-S295 PolarHBondContact O-N 2.9Å; V292-V299 HydrophobicContact CG2-CG1 4.13Å; V292-L300 HydrophobicContact CG1-CD1 4Å; V292-L300 HydrophobicContact CG2-CB 4.06Å; V292-L300 HydrophobicContact CG2-CD1 4.17Å; V292-T313 HydrophobicContact CG1-CG2 3.78Å; V292-P314 HydrophobicContact CB-CG 4.2Å; V292-P314 HydrophobicContact CG1-CG 4.31Å; V292-P314 HydrophobicContact CG2-CG 3.78Å
293E97.6Very high98Very high146 Ų14646 Ų4668%0.68225%0.249SC*.Hα-helixtrans-61.4-40.7172.7-173.4171.6-17000111.4C289 Q290 S295C289-E293 PolarHBondContact O-N 3.42Å; Q290-E293 WeakPolarHBondContact O-CB 3.25Å; Q290-E293 PolarHBondContact O-N 3.19Å; Q290-E293 VanDerWaalsContact O-N 3.13Å; E293-S295 PolarHBondContact O-N 2.97Å
294D96.9Very high98Very high109 Ų10949.2 Ų49.258%0.58326%0.26SS*.THydrogen-bonded Turntrans-73.611.8173.6-60.4-22.2000113Q290 A291 V292 N296Q290-D294 PolarHBondContact NE2-OD1 2.92Å; Q290-D294 PolarHBondContact NE2-OD2 2.81Å; Q290-D294 WeakPolarHBondContact O-CB 3.41Å; Q290-D294 PolarHBondContact O-N 2.98Å; A291-D294 CarbonylContact O-C 3.57Å; V292-D294 VanDerWaalsContact C-N 3.31Å; D294-N296 VanDerWaalsContact C-N 3.34Å; D294-N296 PolarHBondContact O-N 2.99Å
295S96.9Very high97.8Very high103 Ų10354.5 Ų54.572%0.7228%0.28SS*.THydrogen-bonded Turntrans63.928.4175.5-57.40000115.2A291 V292 E293 S297A291-S295 PolarHBondContact O-N 3.39Å; V292-S295 WeakPolarHBondContact O-CA 3.4Å; V292-S295 PolarHBondContact O-N 2.9Å; E293-S295 PolarHBondContact O-N 2.97Å; S295-S297 PolarHBondContact O-N 3.16Å
296N97.4Very high97.7Very high27 Ų2754.8 Ų54.814%0.14428%0.282CS..  trans-7295.7172.4-170.7-39.1000111.1D177 A291 D294 Q298 V299 L300D177-N296 PolarHBondContact OD1-ND2 3.35Å; A291-N296 HydrophobicContact CB-CB 4.23Å; A291-N296 WeakPolarHBondContact O-CB 3.31Å; A291-N296 PolarHBondContact O-N 3.49Å; D294-N296 VanDerWaalsContact C-N 3.34Å; D294-N296 PolarHBondContact O-N 2.99Å; N296-Q298 VanDerWaalsContact C-N 3.32Å; N296-Q298 PolarHBondContact O-N 3.04Å; N296-Q298 PolarHBondContact OD1-N 3.24Å; N296-V299 HydrophobicContact CB-CB 4.19Å; N296-V299 HydrophobicContact CB-CG2 4.23Å; N296-V299 PolarHBondContact O-N 3.49Å; N296-V299 PolarHBondContact OD1-N 3.21Å; N296-L300 PolarHBondContact O-N 3.46Å; N296-L300 VanDerWaalsContact O-N 3.11Å
297S97.1Very high97.5Very high96 Ų9652.9 Ų52.967%0.67127%0.271SS*.Hα-helixtrans-63.3-31.2-177.662.80000114.5S295 K301S295-S297 PolarHBondContact O-N 3.16Å; S297-K301 WeakPolarHBondContact O-CB 3.23Å; S297-K301 PolarHBondContact O-N 3.35Å
298Q97.3Very high97.2Very high75 Ų7553.9 Ų53.935%0.3529%0.29SS..Hα-helixtrans-70.3-45.2178.6179.956.648.200110.6N296 L300 K301 D302N296-Q298 VanDerWaalsContact C-N 3.32Å; N296-Q298 PolarHBondContact O-N 3.04Å; N296-Q298 PolarHBondContact OD1-N 3.24Å; Q298-L300 PolarHBondContact O-N 2.88Å; Q298-K301 PolarHBondContact O-N 3.28Å; Q298-D302 PolarHBondContact NE2-OD2 3.41Å; Q298-D302 PolarHBondContact O-N 3.49Å
299V98.1Very high97Very high2 Ų256.6 Ų56.61%0.01231%0.305CS..Hα-helixtrans-60.2-45.9174.91720000110.8L176 W253 L288 A291 V292 N296 K301 D302 V303L176-V299 HydrophobicContact CB-CG2 3.84Å; W253-V299 HydrophobicContact CZ2-CG1 4.44Å; L288-V299 HydrophobicContact CD2-CG1 3.56Å; A291-V299 HydrophobicContact CB-CB 4.32Å; A291-V299 HydrophobicContact CB-CG1 4.07Å; A291-V299 HydrophobicContact CB-CG2 4.19Å; V292-V299 HydrophobicContact CG2-CG1 4.13Å; N296-V299 HydrophobicContact CB-CB 4.19Å; N296-V299 HydrophobicContact CB-CG2 4.23Å; N296-V299 PolarHBondContact O-N 3.49Å; N296-V299 PolarHBondContact OD1-N 3.21Å; V299-K301 VanDerWaalsContact C-N 3.34Å; V299-K301 PolarHBondContact O-N 2.97Å; V299-D302 PolarHBondContact O-N 3.17Å; V299-V303 HydrophobicContact CG1-CG2 4.25Å; V299-V303 WeakPolarHBondContact O-CG2 3.46Å; V299-V303 PolarHBondContact O-N 2.88Å
300L98.3Very high96.8Very high34 Ų3462.5 Ų62.518%0.17834%0.336CS..Hα-helixtrans-58.3-45.2177.5-18057.4000112.2V292 N296 Q298 D302 V303 R304 T313V292-L300 HydrophobicContact CG1-CD1 4Å; V292-L300 HydrophobicContact CG2-CB 4.06Å; V292-L300 HydrophobicContact CG2-CD1 4.17Å; N296-L300 PolarHBondContact O-N 3.46Å; N296-L300 VanDerWaalsContact O-N 3.11Å; Q298-L300 PolarHBondContact O-N 2.88Å; L300-D302 VanDerWaalsContact C-N 3.35Å; L300-D302 PolarHBondContact O-N 3.3Å; L300-V303 PolarHBondContact O-N 3.13Å; L300-R304 HydrophobicContact CD1-CG 4.41Å; L300-R304 WeakPolarHBondContact O-CG 3.22Å; L300-R304 PolarHBondContact O-N 3Å; L300-T313 HydrophobicContact CD1-CG2 4.13Å
301K97.9Very high96.7Very high144 Ų14462.4 Ų62.463%0.62635%0.35SS*.Hα-helixtrans-61-43.8176.9-177.9-177.7177.7-176.90111.7S297 Q298 V299 R305S297-K301 WeakPolarHBondContact O-CB 3.23Å; S297-K301 PolarHBondContact O-N 3.35Å; Q298-K301 PolarHBondContact O-N 3.28Å; V299-K301 VanDerWaalsContact C-N 3.34Å; V299-K301 PolarHBondContact O-N 2.97Å; K301-R305 PolarHBondContact O-N 2.95Å; K301-R305 VanDerWaalsContact O-N 3.12Å
302D98Very high96.7Very high14 Ų1462.6 Ų62.68%0.07535%0.349CS..Hα-helixtrans-67.6-41.3178.5-83.6-36.4000112.2W253 R257 Q298 V299 L300 R305 V306W253-D302 HydrophobicContact CH2-CB 3.86Å; W253-D302 HydrophobicContact CZ2-CB 3.54Å; R257-D302 HydrophobicContact CB-CB 4.39Å; R257-D302 IonicContact NH1-OD2 3.56Å; Q298-D302 PolarHBondContact NE2-OD2 3.41Å; Q298-D302 PolarHBondContact O-N 3.49Å; V299-D302 PolarHBondContact O-N 3.17Å; L300-D302 VanDerWaalsContact C-N 3.35Å; L300-D302 PolarHBondContact O-N 3.3Å; D302-R305 PolarHBondContact O-N 2.83Å; D302-R305 IonicContact OD1-CZ 3.38Å; D302-R305 IonicContact OD1-NE 3.96Å; D302-R305 PolarHBondContact OD1-NE 2.83Å; D302-R305 IonicContact OD1-NH2 3.88Å; D302-R305 PolarHBondContact OD1-NH2 2.99Å; D302-V306 VanDerWaalsContact O-CG2 3.29Å; D302-V306 WeakPolarHBondContact O-CG2 3.24Å; D302-V306 PolarHBondContact O-N 3.5Å
303V97.9Very high96.6Very high0 Ų064.4 Ų64.40%036%0.36CS..Hα-helixtrans-59-51.7175.3169.70000110.3W253 L288 V299 L300 R305 V306 V307 Y312 P314 L320W253-V303 HydrophobicContact CH2-CB 4.47Å; W253-V303 HydrophobicContact CH2-CG2 3.66Å; W253-V303 HydrophobicContact CZ2-CG2 4.2Å; W253-V303 HydrophobicContact CZ3-CG2 4.34Å; L288-V303 HydrophobicContact CB-CG2 4.46Å; L288-V303 HydrophobicContact CD1-CG2 4.43Å; L288-V303 HydrophobicContact CD2-CG2 3.91Å; V299-V303 HydrophobicContact CG1-CG2 4.25Å; V299-V303 WeakPolarHBondContact O-CG2 3.46Å; V299-V303 PolarHBondContact O-N 2.88Å; L300-V303 PolarHBondContact O-N 3.13Å; V303-R305 VanDerWaalsContact C-N 3.28Å; V303-R305 PolarHBondContact O-N 3.12Å; V303-V306 PolarHBondContact O-N 2.8Å; V303-V306 VanDerWaalsContact O-N 3.12Å; V303-V307 HydrophobicContact CG1-CG1 4.32Å; V303-V307 WeakPolarHBondContact O-CG2 3.48Å; V303-V307 PolarHBondContact O-N 3.47Å; V303-Y312 HydrophobicContact CG1-CD1 4.1Å; V303-Y312 HydrophobicContact CG1-CE1 4.16Å; V303-P314 HydrophobicContact CG1-CG 4.03Å; V303-L320 HydrophobicContact CG1-CD1 3.89Å
304R97.2Very high96.6Very high71 Ų7157.6 Ų57.627%0.26833%0.329SS..Hα-helixtrans-53.6-45178.3-76172175.1175.41.3112.4L300 V307 G308 D309 D310 Y312 T313L300-R304 HydrophobicContact CD1-CG 4.41Å; L300-R304 WeakPolarHBondContact O-CG 3.22Å; L300-R304 PolarHBondContact O-N 3Å; R304-V307 WeakPolarHBondContact O-CG2 3.48Å; R304-G308 WeakPolarHBondContact O-CA 3.32Å; R304-G308 PolarHBondContact O-N 3.36Å; R304-D309 WeakPolarHBondContact CB-O 3.37Å; R304-D309 WeakPolarHBondContact CG-O 2.83Å; R304-D309 PolarHBondContact O-N 3.17Å; R304-D310 VanDerWaalsContact CD-O 3.23Å; R304-D310 WeakPolarHBondContact CD-O 3.43Å; R304-D310 PolarHBondContact NE-O 3.24Å; R304-Y312 VanDerWaalsContact CG-O 3.22Å; R304-Y312 WeakPolarHBondContact CG-O 3.16Å; R304-Y312 PolarHBondContact NE-O 2.85Å; R304-T313 PolarHBondContact NH2-OG1 3.37Å
305R95.8Very high96.5Very high111 Ų11160.5 Ų60.542%0.41934%0.339SS..Hα-helixtrans-62.4-48.9176177-176.557.288.7-1112.3R257 K301 D302 V303 G308R257-R305 VanDerWaalsContact O-CZ 3.26Å; R257-R305 PolarHBondContact O-NH1 3.34Å; R257-R305 PolarHBondContact O-NH2 3.18Å; K301-R305 PolarHBondContact O-N 2.95Å; K301-R305 VanDerWaalsContact O-N 3.12Å; D302-R305 PolarHBondContact O-N 2.83Å; D302-R305 IonicContact OD1-CZ 3.38Å; D302-R305 IonicContact OD1-NE 3.96Å; D302-R305 PolarHBondContact OD1-NE 2.83Å; D302-R305 IonicContact OD1-NH2 3.88Å; D302-R305 PolarHBondContact OD1-NH2 2.99Å; V303-R305 VanDerWaalsContact C-N 3.28Å; V303-R305 PolarHBondContact O-N 3.12Å; R305-G308 PolarHBondContact O-N 2.89Å
306V95.9Very high96.5Very high7 Ų759.4 Ų59.44%0.04233%0.325CS..Hα-helixtrans-65.5-40.6-177.6174.30000110.8W253 L256 D302 V303 G308 L324W253-V306 HydrophobicContact CZ3-CG2 4.49Å; L256-V306 HydrophobicContact CD1-CG1 4.1Å; L256-V306 HydrophobicContact CD2-CG1 3.81Å; L256-V306 HydrophobicContact CG-CG1 3.87Å; L256-V306 HydrophobicContact CG-CG2 4.41Å; D302-V306 VanDerWaalsContact O-CG2 3.29Å; D302-V306 WeakPolarHBondContact O-CG2 3.24Å; D302-V306 PolarHBondContact O-N 3.5Å; V303-V306 PolarHBondContact O-N 2.8Å; V303-V306 VanDerWaalsContact O-N 3.12Å; V306-G308 VanDerWaalsContact C-N 3.28Å; V306-G308 PolarHBondContact O-N 2.9Å; V306-L324 HydrophobicContact CB-CD2 4.35Å; V306-L324 HydrophobicContact CG1-CD2 3.43Å; V306-L324 VanDerWaalsContact CG1-CD2 3.43Å
307V94.8Very high96.6Very high6 Ų659.6 Ų59.64%0.03633%0.328CS..Hα-helixtrans-73.8-22.2176.1-57.70000112.5V303 R304 D309 Y312 L320 R323 L324 R418V303-V307 HydrophobicContact CG1-CG1 4.32Å; V303-V307 WeakPolarHBondContact O-CG2 3.48Å; V303-V307 PolarHBondContact O-N 3.47Å; R304-V307 WeakPolarHBondContact O-CG2 3.48Å; V307-D309 HydrophobicContact CG2-CB 3.88Å; V307-Y312 HydrophobicContact CG1-CD1 4.29Å; V307-Y312 HydrophobicContact CG1-CE1 4.39Å; V307-Y312 HydrophobicContact CG2-CD1 3.71Å; V307-Y312 HydrophobicContact CG2-CG 4.25Å; V307-L320 HydrophobicContact CG1-CD1 4.36Å; V307-R323 HydrophobicContact CG1-CB 4.02Å; V307-L324 HydrophobicContact CG1-CD2 3.74Å; V307-L324 HydrophobicContact CG1-CG 4.38Å; V307-R418 PolarHBondContact O-NE 2.94Å; V307-R418 PolarHBondContact O-NH2 2.78Å
308G92.6Very high96.6Very high61 Ų6159.7 Ų59.763%0.62932%0.316SS*.THydrogen-bonded Turntrans74.434.8-176.600000112.9R304 R305 V306R304-G308 WeakPolarHBondContact O-CA 3.32Å; R304-G308 PolarHBondContact O-N 3.36Å; R305-G308 PolarHBondContact O-N 2.89Å; V306-G308 VanDerWaalsContact C-N 3.28Å; V306-G308 PolarHBondContact O-N 2.9Å
309D94.1Very high96.6Very high57 Ų5759.6 Ų59.631%0.30532%0.315SS..  trans-143.6103.1-177.1-179.4-6.9000109.4R304 V307 A311 Y312 R323R304-D309 WeakPolarHBondContact CB-O 3.37Å; R304-D309 WeakPolarHBondContact CG-O 2.83Å; R304-D309 PolarHBondContact O-N 3.17Å; V307-D309 HydrophobicContact CG2-CB 3.88Å; D309-A311 VanDerWaalsContact C-N 3.27Å; D309-A311 PolarHBondContact O-N 3.11Å; D309-A311 PolarHBondContact OD1-N 2.92Å; D309-A311 VanDerWaalsContact OD1-N 3.14Å; D309-Y312 WeakPolarHBondContact O-CB 3.31Å; D309-Y312 PolarHBondContact O-N 3.42Å; D309-Y312 PolarHBondContact OD1-N 3.15Å; D309-R323 IonicContact OD2-NH1 2.58Å; D309-R323 PolarHBondContact OD2-NH1 3.18Å
310D94.8Very high96.6Very high135 Ų13559.5 Ų59.572%0.72232%0.315SS*.THydrogen-bonded Turntrans-70.2-20.4-175.5-71.4-30.4000113.7R304R304-D310 VanDerWaalsContact CD-O 3.23Å; R304-D310 WeakPolarHBondContact CD-O 3.43Å; R304-D310 PolarHBondContact NE-O 3.24Å
311A96.4Very high96.6Very high85 Ų8557.9 Ų57.970%0.70231%0.306SS*.THydrogen-bonded Turntrans-88-13.7178.200000112.2D309D309-A311 VanDerWaalsContact C-N 3.27Å; D309-A311 PolarHBondContact O-N 3.11Å; D309-A311 PolarHBondContact OD1-N 2.92Å; D309-A311 VanDerWaalsContact OD1-N 3.14Å
312Y97.2Very high96.6Very high13 Ų1352.7 Ų52.75%0.05129%0.29CS..  trans-68.3137.4-174.1-174.3-122.4000112.7V303 R304 V307 D309 P314 E319 L320 R323V303-Y312 HydrophobicContact CG1-CD1 4.1Å; V303-Y312 HydrophobicContact CG1-CE1 4.16Å; R304-Y312 VanDerWaalsContact CG-O 3.22Å; R304-Y312 WeakPolarHBondContact CG-O 3.16Å; R304-Y312 PolarHBondContact NE-O 2.85Å; V307-Y312 HydrophobicContact CG1-CD1 4.29Å; V307-Y312 HydrophobicContact CG1-CE1 4.39Å; V307-Y312 HydrophobicContact CG2-CD1 3.71Å; V307-Y312 HydrophobicContact CG2-CG 4.25Å; D309-Y312 WeakPolarHBondContact O-CB 3.31Å; D309-Y312 PolarHBondContact O-N 3.42Å; D309-Y312 PolarHBondContact OD1-N 3.15Å; Y312-P314 HydrophobicContact CE1-CB 3.87Å; Y312-E319 WeakPolarHBondContact CE2-OE1 3.41Å; Y312-E319 VanDerWaalsContact CE2-OE2 3.3Å; Y312-E319 WeakPolarHBondContact CE2-OE2 3.19Å; Y312-E319 PolarHBondContact OH-OE1 3.41Å; Y312-E319 PolarHBondContact OH-OE2 2.88Å; Y312-L320 HydrophobicContact CE1-CD1 3.97Å; Y312-R323 VanDerWaalsContact CD2-CZ 3.46Å
313T97.4Very high96.5Very high57 Ų5755.5 Ų55.535%0.3530%0.3SS..  trans-134.8111.6172.3-55.80000107.5V292 L300 R304 Q315V292-T313 HydrophobicContact CG1-CG2 3.78Å; L300-T313 HydrophobicContact CD1-CG2 4.13Å; R304-T313 PolarHBondContact NH2-OG1 3.37Å; T313-Q315 PolarHBondContact O-N 3.03Å
314P96.5Very high96.5Very high3 Ų355.6 Ų55.62%0.01930%0.3CS..  trans-70.3120.2-174.630.5-37.5000111V292 V303 Y312 L320V292-P314 HydrophobicContact CB-CG 4.2Å; V292-P314 HydrophobicContact CG1-CG 4.31Å; V292-P314 HydrophobicContact CG2-CG 3.78Å; V303-P314 HydrophobicContact CG1-CG 4.03Å; Y312-P314 HydrophobicContact CE1-CB 3.87Å; P314-L320 HydrophobicContact CB-CB 4.32Å; P314-L320 HydrophobicContact CB-CD1 4.25Å; P314-L320 HydrophobicContact CB-CD2 3.99Å; P314-L320 HydrophobicContact CB-CG 4.43Å
315Q95.3Very high96.5Very high169 Ų16952.2 Ų52.279%0.7929%0.288SS*.  trans-114.1-28174.4-65.9179.7-7.900112.4T313T313-Q315 PolarHBondContact O-N 3.03Å
316N97.4Very high96.7Very high80 Ų8047 Ų4743%0.42827%0.269SS..  trans-118.2120.1-177.8-173.1-39.6000109.9K318 E319 L320N316-K318 PolarHBondContact O-N 3.13Å; N316-K318 WeakPolarHBondContact OD1-CB 3.25Å; N316-K318 PolarHBondContact OD1-N 3.42Å; N316-E319 HydrophobicContact CB-CB 4.06Å; N316-E319 PolarHBondContact O-N 2.98Å; N316-E319 VanDerWaalsContact O-N 3.1Å; N316-L320 PolarHBondContact O-N 2.94Å
317P98.1Very high96.8Very high32 Ų3246.7 Ų46.721%0.20827%0.266CS..Hα-helixtrans-56.3-33.5179.1-28.235.8000113.8C285 V286 C289 C321C285-P317 HydrophobicContact CB-CB 4.23Å; V286-P317 HydrophobicContact CB-CG 4.39Å; V286-P317 HydrophobicContact CG2-CB 3.8Å; V286-P317 HydrophobicContact CG2-CG 3.86Å; C289-P317 HydrophobicContact CB-CG 4.21Å; P317-C321 WeakPolarHBondContact O-CB 3.3Å; P317-C321 PolarHBondContact O-N 3.36Å
318K97.8Very high97Very high97 Ų9746.5 Ų46.542%0.42227%0.265SS..Hα-helixtrans-69.2-40.1178.3-58.8-169.6-173.4-155.20112.2N316 C321 A322 E349 I350N316-K318 PolarHBondContact O-N 3.13Å; N316-K318 WeakPolarHBondContact OD1-CB 3.25Å; N316-K318 PolarHBondContact OD1-N 3.42Å; K318-C321 WeakPolarHBondContact O-CB 3.35Å; K318-C321 PolarHBondContact O-N 3.43Å; K318-A322 PolarHBondContact O-N 3.22Å; K318-E349 VanDerWaalsContact CD-O 3.25Å; K318-E349 WeakPolarHBondContact CD-O 3.4Å; K318-E349 WeakPolarHBondContact CE-O 3.37Å; K318-E349 PolarHBondContact NZ-O 3.05Å; K318-I350 WeakPolarHBondContact CA-O 3.45Å
319E97.7Very high97.2Very high73 Ų7344.2 Ų44.234%0.34124%0.238SC..Hα-helixtrans-68.7-41.8178.3-168.9-12315500111Y312 N316 C321 A322 R323Y312-E319 WeakPolarHBondContact CE2-OE1 3.41Å; Y312-E319 VanDerWaalsContact CE2-OE2 3.3Å; Y312-E319 WeakPolarHBondContact CE2-OE2 3.19Å; Y312-E319 PolarHBondContact OH-OE1 3.41Å; Y312-E319 PolarHBondContact OH-OE2 2.88Å; N316-E319 HydrophobicContact CB-CB 4.06Å; N316-E319 PolarHBondContact O-N 2.98Å; N316-E319 VanDerWaalsContact O-N 3.1Å; E319-C321 VanDerWaalsContact C-N 3.35Å; E319-A322 WeakPolarHBondContact O-CB 3.05Å; E319-A322 PolarHBondContact O-N 3.41Å; E319-R323 PolarHBondContact O-N 3.45Å; E319-R323 IonicContact OE1-CZ 2.71Å; E319-R323 IonicContact OE1-NE 3.86Å; E319-R323 PolarHBondContact OE1-NE 3.24Å; E319-R323 IonicContact OE1-NH2 2.8Å; E319-R323 PolarHBondContact OE1-NH2 3.41Å
320L98.2Very high97.4Very high0 Ų042 Ų420%023%0.226CC..Hα-helixtrans-61.3-44.9172.4177.860.7000111.3C285 L288 V303 V307 Y312 P314 N316 A322 R323 L324C285-L320 HydrophobicContact CB-CD2 4.05Å; C285-L320 HydrophobicContact CB-CG 4.3Å; L288-L320 HydrophobicContact CB-CD2 3.65Å; L288-L320 HydrophobicContact CD1-CD2 3.92Å; L288-L320 HydrophobicContact CG-CD2 4.44Å; V303-L320 HydrophobicContact CG1-CD1 3.89Å; V307-L320 HydrophobicContact CG1-CD1 4.36Å; Y312-L320 HydrophobicContact CE1-CD1 3.97Å; P314-L320 HydrophobicContact CB-CB 4.32Å; P314-L320 HydrophobicContact CB-CD1 4.25Å; P314-L320 HydrophobicContact CB-CD2 3.99Å; P314-L320 HydrophobicContact CB-CG 4.43Å; N316-L320 PolarHBondContact O-N 2.94Å; L320-A322 VanDerWaalsContact C-N 3.3Å; L320-A322 PolarHBondContact O-N 3.02Å; L320-R323 PolarHBondContact O-N 3.01Å; L320-R323 VanDerWaalsContact O-N 3.1Å; L320-L324 HydrophobicContact CD1-CD1 3.62Å; L320-L324 HydrophobicContact CD1-CG 3.91Å; L320-L324 HydrophobicContact CD2-CD1 4.48Å; L320-L324 HydrophobicContact CG-CD1 3.88Å; L320-L324 HydrophobicContact CG-CG 4.4Å; L320-L324 WeakPolarHBondContact O-CG 3.45Å; L320-L324 PolarHBondContact O-N 3.32Å
321C98.1Very high97.3Very high0 Ų036 Ų360%020%0.196CC..Hα-helixtrans-57.3-41.5176-170.50000111.5P317 K318 E319 R323 L324 F325 I350P317-C321 WeakPolarHBondContact O-CB 3.3Å; P317-C321 PolarHBondContact O-N 3.36Å; K318-C321 WeakPolarHBondContact O-CB 3.35Å; K318-C321 PolarHBondContact O-N 3.43Å; E319-C321 VanDerWaalsContact C-N 3.35Å; C321-R323 PolarHBondContact O-N 3.2Å; C321-L324 PolarHBondContact O-N 2.97Å; C321-F325 WeakPolarHBondContact O-CA 3.37Å; C321-F325 VanDerWaalsContact O-CB 3.26Å; C321-F325 WeakPolarHBondContact O-CB 3.31Å; C321-F325 PolarHBondContact O-N 2.9Å; C321-I350 VanDerWaalsContact CB-O 3.27Å; C321-I350 WeakPolarHBondContact CB-O 3.48Å; C321-I350 PolarHBondContact SG-O 3.03Å
322A97.1Very high96.9Very high35 Ų3532.3 Ų32.329%0.28917%0.165SC..Hα-helixtrans-58.5-36.9176.900000112.9K318 E319 L320 G351 T353K318-A322 PolarHBondContact O-N 3.22Å; E319-A322 WeakPolarHBondContact O-CB 3.05Å; E319-A322 PolarHBondContact O-N 3.41Å; L320-A322 VanDerWaalsContact C-N 3.3Å; L320-A322 PolarHBondContact O-N 3.02Å; A322-G351 WeakPolarHBondContact CA-O 3.48Å; A322-G351 WeakPolarHBondContact CB-O 3.08Å; A322-G351 PolarHBondContact N-O 3.49Å; A322-T353 PolarHBondContact O-OG1 2.82Å
323R96.1Very high96.3Very high73 Ų7337.2 Ų37.228%0.27519%0.188SC..Hα-helixtrans-78.1-34-179.3-64.6-178.8-176.8-127.14.9112.8V307 D309 Y312 E319 L320 C321 R418V307-R323 HydrophobicContact CG1-CB 4.02Å; D309-R323 IonicContact OD2-NH1 2.58Å; D309-R323 PolarHBondContact OD2-NH1 3.18Å; Y312-R323 VanDerWaalsContact CD2-CZ 3.46Å; E319-R323 PolarHBondContact O-N 3.45Å; E319-R323 IonicContact OE1-CZ 2.71Å; E319-R323 IonicContact OE1-NE 3.86Å; E319-R323 PolarHBondContact OE1-NE 3.24Å; E319-R323 IonicContact OE1-NH2 2.8Å; E319-R323 PolarHBondContact OE1-NH2 3.41Å; L320-R323 PolarHBondContact O-N 3.01Å; L320-R323 VanDerWaalsContact O-N 3.1Å; C321-R323 PolarHBondContact O-N 3.2Å; R323-R418 PolarHBondContact O-NH1 2.9Å
324L97.4Very high95.6Very high2 Ų234.9 Ų34.91%0.0117%0.174CC..Hα-helixtrans-97.7-24.1-173.7-64.7-174.7000114.1L256 G263 F264 M284 L288 V306 V307 L320 C321L256-L324 HydrophobicContact CD2-CD1 4.43Å; L256-L324 HydrophobicContact CD2-CD2 4.36Å; G263-L324 CarbonylContact C-O 3.2Å; G263-L324 WeakPolarHBondContact CA-O 3.31Å; F264-L324 PolarHBondContact N-O 3.49Å; M284-L324 HydrophobicContact CE-CD1 4.2Å; L288-L324 HydrophobicContact CD1-CD1 4.28Å; V306-L324 HydrophobicContact CB-CD2 4.35Å; V306-L324 HydrophobicContact CG1-CD2 3.43Å; V306-L324 VanDerWaalsContact CG1-CD2 3.43Å; V307-L324 HydrophobicContact CG1-CD2 3.74Å; V307-L324 HydrophobicContact CG1-CG 4.38Å; L320-L324 HydrophobicContact CD1-CD1 3.62Å; L320-L324 HydrophobicContact CD1-CG 3.91Å; L320-L324 HydrophobicContact CD2-CD1 4.48Å; L320-L324 HydrophobicContact CG-CD1 3.88Å; L320-L324 HydrophobicContact CG-CG 4.4Å; L320-L324 WeakPolarHBondContact O-CG 3.45Å; L320-L324 PolarHBondContact O-N 3.32Å; C321-L324 PolarHBondContact O-N 2.97Å
325F98.6Very high95Very high0 Ų036.1 Ų36.10%018%0.182CC..EExtended strand (participates in β ladder)trans-128.1121.6-164.4-169.4-150.5000112.7F264 L266 A278 V281 C321 T327 I350 T353 L425F264-F325 HydrophobicContact CB-CD2 3.8Å; F264-F325 HydrophobicContact CB-CE2 4.2Å; L266-F325 HydrophobicContact CB-CE2 3.44Å; L266-F325 VanDerWaalsContact CB-CE2 3.44Å; L266-F325 HydrophobicContact CB-CZ 3.6Å; L266-F325 HydrophobicContact CD2-CE2 4.35Å; L266-F325 HydrophobicContact CD2-CZ 3.64Å; L266-F325 HydrophobicContact CG-CZ 4.26Å; A278-F325 HydrophobicContact CB-CE1 4.04Å; A278-F325 HydrophobicContact CB-CZ 4.29Å; V281-F325 HydrophobicContact CB-CD1 4.09Å; V281-F325 HydrophobicContact CB-CE1 3.99Å; V281-F325 HydrophobicContact CB-CG 4.42Å; V281-F325 HydrophobicContact CB-CZ 4.2Å; V281-F325 HydrophobicContact CG1-CB 3.92Å; V281-F325 HydrophobicContact CG1-CD1 3.64Å; V281-F325 HydrophobicContact CG1-CD2 4.05Å; V281-F325 HydrophobicContact CG1-CE1 4.06Å; V281-F325 HydrophobicContact CG1-CE2 4.41Å; V281-F325 HydrophobicContact CG1-CG 3.63Å; V281-F325 HydrophobicContact CG1-CZ 4.41Å; V281-F325 HydrophobicContact CG2-CE1 4.36Å; V281-F325 HydrophobicContact CG2-CE2 4.15Å; V281-F325 HydrophobicContact CG2-CZ 4.06Å; C321-F325 WeakPolarHBondContact O-CA 3.37Å; C321-F325 VanDerWaalsContact O-CB 3.26Å; C321-F325 WeakPolarHBondContact O-CB 3.31Å; C321-F325 PolarHBondContact O-N 2.9Å; F325-T327 HydrophobicContact CD1-CG2 4Å; F325-T327 HydrophobicContact CE1-CG2 3.48Å; F325-T327 VanDerWaalsContact CE1-CG2 3.48Å; F325-T327 HydrophobicContact CE2-CG2 4.07Å; F325-T327 HydrophobicContact CG-CG2 4.5Å; F325-T327 HydrophobicContact CZ-CG2 3.54Å; F325-I350 HydrophobicContact CD1-CD1 4.12Å; F325-I350 HydrophobicContact CE1-CD1 3.82Å; F325-T353 PolarHBondContact O-N 3.24Å; F325-L425 HydrophobicContact CE2-CD1 4.23Å
326T98.7Very high94.5Very high3 Ų329.3 Ų29.32%0.01815%0.153CC..EExtended strand (participates in β ladder)trans-110.2121173.6-51.50000109F264 L265 L266 T353 V355 R416F264-T326 PolarHBondContact O-N 2.96Å; L265-T326 CarbonylContact C-O 3.49Å; L265-T326 VanDerWaalsContact CA-O 3.27Å; L265-T326 WeakPolarHBondContact CA-O 3.3Å; L266-T326 PolarHBondContact N-O 3.09Å; T326-T353 CarbonylContact C-O 3.56Å; T326-T353 VanDerWaalsContact CA-O 3.28Å; T326-T353 WeakPolarHBondContact CA-O 3.5Å; T326-T353 HydrophobicContact CG2-CG2 4.49Å; T326-V355 HydrophobicContact CG2-CG2 4.23Å; T326-R416 PolarHBondContact OG1-NH2 3.43Å; T326-R416 VanDerWaalsContact OG1-NH2 3.07Å
327T98.8Very high94.1Very high0 Ų031.5 Ų31.50%016%0.161CC..EExtended strand (participates in β ladder)trans-104.2143.2174.355.40000109.6L266 L268 F325 S352 T353 H354 V355L266-T327 CarbonylContact O-C 3.52Å; L266-T327 WeakPolarHBondContact O-CA 3.1Å; L268-T327 HydrophobicContact CB-CG2 4.47Å; L268-T327 HydrophobicContact CD2-CG2 4.1Å; F325-T327 HydrophobicContact CD1-CG2 4Å; F325-T327 HydrophobicContact CE1-CG2 3.48Å; F325-T327 VanDerWaalsContact CE1-CG2 3.48Å; F325-T327 HydrophobicContact CE2-CG2 4.07Å; F325-T327 HydrophobicContact CG-CG2 4.5Å; F325-T327 HydrophobicContact CZ-CG2 3.54Å; T327-S352 WeakPolarHBondContact CG2-OG 3.5Å; T327-S352 PolarHBondContact OG1-OG 2.84Å; T327-T353 PolarHBondContact N-O 2.88Å; T327-H354 CarbonylContact O-C 3.53Å; T327-H354 WeakPolarHBondContact O-CA 3.11Å; T327-H354 PolarHBondContact OG1-ND1 2.9Å; T327-V355 PolarHBondContact O-N 3.48Å
328C98.2Very high93.6Very high2 Ų235.1 Ų35.11%0.01418%0.178CC..EExtended strand (participates in β ladder)trans-133.7112.8-178.4-172.30000111.3L266 P267 L268 M330 V355L266-C328 PolarHBondContact O-N 3.16Å; P267-C328 CarbonylContact C-O 3.5Å; P267-C328 WeakPolarHBondContact CA-O 3.42Å; L268-C328 PolarHBondContact N-O 3.11Å; C328-M330 HydrophobicContact CB-CE 3.97Å; C328-V355 CarbonylContact C-O 3.54Å; C328-V355 VanDerWaalsContact CA-O 3.29Å; C328-V355 WeakPolarHBondContact CA-O 3.27Å; C328-V355 HydrophobicContact CB-CB 4.5Å
329Y97.9Very high93.2Very high13 Ų1331 Ų315%0.05116%0.162CC..EExtended strand (participates in β ladder)trans-86.6129.4167.7-179.4-90000109.4L268 S335 T339 C340 A343 V355 N356 I357L268-Y329 WeakPolarHBondContact O-CA 3.39Å; L268-Y329 WeakPolarHBondContact O-CD2 3.35Å; Y329-S335 WeakPolarHBondContact OH-CB 3.34Å; Y329-T339 PolarHBondContact OH-OG1 2.91Å; Y329-C340 HydrophobicContact CD1-CB 4.22Å; Y329-C340 HydrophobicContact CE1-CB 3.63Å; Y329-C340 HydrophobicContact CE2-CB 4.25Å; Y329-C340 PolarHBondContact OH-N 3.39Å; Y329-A343 HydrophobicContact CD2-CB 3.67Å; Y329-A343 HydrophobicContact CE2-CB 4.46Å; Y329-A343 HydrophobicContact CG-CB 4.3Å; Y329-V355 PolarHBondContact N-O 3.34Å; Y329-N356 WeakPolarHBondContact CD1-OD1 3.27Å; Y329-N356 WeakPolarHBondContact O-CA 3.35Å; Y329-I357 PolarHBondContact O-N 3.21Å
330M96.9Very high93Very high11 Ų1128 Ų285%0.05415%0.148CC..EExtended strand (participates in β ladder)trans-121.682-174.9-51.5-174.8-162.900110.2P267 C328 I357 I359 R401 L404 A405P267-M330 HydrophobicContact CB-CE 4.07Å; P267-M330 HydrophobicContact CG-CE 4.19Å; C328-M330 HydrophobicContact CB-CE 3.97Å; M330-I357 CarbonylContact C-O 3.48Å; M330-I357 WeakPolarHBondContact CA-O 3.22Å; M330-I357 HydrophobicContact CB-CD1 4.37Å; M330-I357 HydrophobicContact CB-CG1 3.99Å; M330-I357 HydrophobicContact CG-CD1 3.71Å; M330-I357 HydrophobicContact CG-CG1 3.7Å; M330-I357 HydrophobicContact SD-CD1 4.07Å; M330-I359 HydrophobicContact CB-CG2 3.93Å; M330-R401 HydrophobicContact CB-CG 3.81Å; M330-R401 HydrophobicContact CG-CG 4.49Å; M330-R401 PolarHBondContact O-NE 2.89Å; M330-R401 VanDerWaalsContact SD-CA 3.57Å; M330-R401 HydrophobicContact SD-CB 3.61Å; M330-R401 HydrophobicContact SD-CG 3.88Å; M330-R401 VanDerWaalsContact SD-O 3.33Å; M330-L404 HydrophobicContact SD-CB 4.16Å; M330-A405 HydrophobicContact CE-CB 3.88Å
331G93.1Very high92.8Very high8 Ų829.3 Ų29.38%0.08216%0.158CC..EExtended strand (participates in β ladder)trans-73.3158.1-178.100000113I357 N358 I359G331-I357 PolarHBondContact N-O 3.42Å; G331-N358 WeakPolarHBondContact O-CA 3.32Å; G331-I359 WeakPolarHBondContact O-CG1 3.31Å; G331-I359 PolarHBondContact O-N 3.21Å
332S89.4Confident92.7Very high8 Ų831.5 Ų31.56%0.05617%0.166CC..  trans-130.6174.8171.862.60000109.9N334 S335 D360 Q397S332-N334 PolarHBondContact O-N 2.97Å; S332-N334 PolarHBondContact OG-N 3.14Å; S332-S335 PolarHBondContact N-OG 3.18Å; S332-S335 WeakPolarHBondContact O-CB 3.47Å; S332-S335 PolarHBondContact O-N 3.34Å; S332-S335 PolarHBondContact OG-OG 3.04Å; S332-D360 VanDerWaalsContact CA-OD1 3.27Å; S332-D360 WeakPolarHBondContact CA-OD1 3.46Å; S332-D360 WeakPolarHBondContact CB-OD1 3.31Å; S332-Q397 PolarHBondContact OG-OE1 3.33Å
333E84.3Confident92.7Very high115 Ų11529.9 Ų29.954%0.53715%0.152SC..THydrogen-bonded Turntrans-57-18.7172.662.9-170.7-168.100113.7D360 K364E333-D360 VanDerWaalsContact N-CG 3.33Å; E333-D360 PolarHBondContact N-OD1 3.44Å; E333-D360 PolarHBondContact N-OD2 3.29Å; E333-K364 WeakPolarHBondContact OE2-CE 3.43Å; E333-K364 IonicContact OE2-NZ 3.1Å; E333-K364 PolarHBondContact OE2-NZ 3.4Å
334N82.4Confident92.8Very high9 Ų931.5 Ų31.55%0.04816%0.159CC..THydrogen-bonded Turntrans-92.9-9.3178.1-55.6-48.2000113.8S332 Q397 L487 E488 P489S332-N334 PolarHBondContact O-N 2.97Å; S332-N334 PolarHBondContact OG-N 3.14Å; N334-Q397 PolarHBondContact ND2-OE1 2.81Å; N334-L487 PolarHBondContact ND2-O 3.28Å; N334-E488 WeakPolarHBondContact CB-O 3.18Å; N334-P489 VanDerWaalsContact OD1-CA 3.29Å; N334-P489 WeakPolarHBondContact OD1-CA 3.18Å
335S84.8Confident92.9Very high29 Ų2935.5 Ų35.520%0.20318%0.18CC..  trans-82.5137.4-172.2-56.90000111.7Y329 S332 E486Y329-S335 WeakPolarHBondContact OH-CB 3.34Å; S332-S335 PolarHBondContact N-OG 3.18Å; S332-S335 WeakPolarHBondContact O-CB 3.47Å; S332-S335 PolarHBondContact O-N 3.34Å; S332-S335 PolarHBondContact OG-OG 3.04Å; S335-E486 WeakPolarHBondContact CA-OE2 3.37Å
336S84.6Confident92.9Very high26 Ų2635.5 Ų35.518%0.18218%0.18CC..  trans-77.9153179.771.30000112.1D338 T339 C340 E486S336-D338 PolarHBondContact O-N 3.37Å; S336-T339 PolarHBondContact O-OG1 3.03Å; S336-T339 VanDerWaalsContact O-OG1 3.07Å; S336-T339 PolarHBondContact OG-N 3.46Å; S336-T339 VanDerWaalsContact OG-N 3.16Å; S336-T339 PolarHBondContact OG-OG1 3.28Å; S336-C340 PolarHBondContact O-N 3.39Å; S336-E486 WeakPolarHBondContact CB-OE1 3.29Å; S336-E486 PolarHBondContact N-OE2 2.96Å; S336-E486 PolarHBondContact OG-OE1 2.75Å; S336-E486 PolarHBondContact OG-OE2 3.08Å
337Q87.1Confident92.9Very high126 Ų12635.3 Ų35.359%0.58918%0.179SC*.Hα-helixtrans-63.5-26.6171-171.962.619.300111.4S341Q337-S341 WeakPolarHBondContact O-CB 3.43Å; Q337-S341 PolarHBondContact O-N 3.45Å; Q337-S341 PolarHBondContact O-OG 2.77Å
338D88.4Confident92.8Very high107 Ų10737.9 Ų37.957%0.57221%0.205SC*.Hα-helixtrans-71.2-44.5-178.1-63.9-19.5000111.8S336 C340 S341 R342S336-D338 PolarHBondContact O-N 3.37Å; D338-C340 VanDerWaalsContact C-N 3.33Å; D338-C340 PolarHBondContact O-N 2.89Å; D338-S341 PolarHBondContact O-N 2.88Å; D338-R342 WeakPolarHBondContact O-CG 3.46Å; D338-R342 PolarHBondContact O-N 3.48Å; D338-R342 PolarHBondContact O-NH1 2.6Å
339T89.7Confident92.8Very high12 Ų1239.6 Ų39.67%0.07421%0.213CC..Hα-helixtrans-62.5-42.3175.451.70000111.4Y329 S336 S341 R342 A343 E486Y329-T339 PolarHBondContact OH-OG1 2.91Å; S336-T339 PolarHBondContact O-OG1 3.03Å; S336-T339 VanDerWaalsContact O-OG1 3.07Å; S336-T339 PolarHBondContact OG-N 3.46Å; S336-T339 VanDerWaalsContact OG-N 3.16Å; S336-T339 PolarHBondContact OG-OG1 3.28Å; T339-S341 PolarHBondContact O-N 2.96Å; T339-R342 PolarHBondContact O-N 2.85Å; T339-A343 WeakPolarHBondContact O-CB 3.46Å; T339-A343 PolarHBondContact O-N 3.37Å; T339-E486 VanDerWaalsContact CG2-CD 3.41Å; T339-E486 HydrophobicContact CG2-CG 4.47Å; T339-E486 WeakPolarHBondContact CG2-OE1 2.98Å; T339-E486 VanDerWaalsContact CG2-OE2 3.32Å; T339-E486 WeakPolarHBondContact CG2-OE2 3.37Å; T339-E486 PolarHBondContact OG1-OE2 3.39Å
340C93.2Very high92.8Very high8 Ų839 Ų395%0.05421%0.21CC..Hα-helixtrans-60.9-44176.3-175.70000111.9Y329 S336 D338 A343 R344 N356Y329-C340 HydrophobicContact CD1-CB 4.22Å; Y329-C340 HydrophobicContact CE1-CB 3.63Å; Y329-C340 HydrophobicContact CE2-CB 4.25Å; Y329-C340 PolarHBondContact OH-N 3.39Å; S336-C340 PolarHBondContact O-N 3.39Å; D338-C340 VanDerWaalsContact C-N 3.33Å; D338-C340 PolarHBondContact O-N 2.89Å; C340-A343 PolarHBondContact O-N 2.75Å; C340-R344 WeakPolarHBondContact O-CB 3.44Å; C340-R344 PolarHBondContact O-N 2.84Å; C340-N356 PolarHBondContact SG-ND2 3.36Å
341S95.2Very high92.9Very high29 Ų2939.2 Ų39.220%0.20322%0.216CC..Hα-helixtrans-66.5-46.2179.7-56.40000111Q337 D338 T339 A343 R344 D345Q337-S341 WeakPolarHBondContact O-CB 3.43Å; Q337-S341 PolarHBondContact O-N 3.45Å; Q337-S341 PolarHBondContact O-OG 2.77Å; D338-S341 PolarHBondContact O-N 2.88Å; T339-S341 PolarHBondContact O-N 2.96Å; S341-A343 VanDerWaalsContact C-N 3.34Å; S341-A343 PolarHBondContact O-N 2.81Å; S341-R344 WeakPolarHBondContact O-CB 3.47Å; S341-R344 PolarHBondContact O-N 3.22Å; S341-R344 VanDerWaalsContact O-N 3.15Å; S341-D345 WeakPolarHBondContact O-CB 3.4Å; S341-D345 PolarHBondContact O-N 3.3Å
342R95.9Very high93.1Very high46 Ų4639.4 Ų39.417%0.17422%0.216CC..Hα-helixtrans-57.7-43.6175.8-70.9-169.7-55.7-92.210.1113G270 D338 T339 L346 I478G270-R342 PolarHBondContact O-NE 3.19Å; G270-R342 VanDerWaalsContact O-NE 3.09Å; D338-R342 WeakPolarHBondContact O-CG 3.46Å; D338-R342 PolarHBondContact O-N 3.48Å; D338-R342 PolarHBondContact O-NH1 2.6Å; T339-R342 PolarHBondContact O-N 2.85Å; R342-L346 WeakPolarHBondContact O-CB 3.4Å; R342-L346 PolarHBondContact O-N 2.87Å; R342-I478 HydrophobicContact CB-CD1 4.5Å; R342-I478 HydrophobicContact CB-CG1 3.93Å; R342-I478 HydrophobicContact CG-CG1 4.22Å
343A97.1Very high93.5Very high0 Ų041.3 Ų41.30%023%0.227CC..Hα-helixtrans-63.1-43.8177.300000111.7L268 Y329 T339 C340 S341 A347L268-A343 HydrophobicContact CD2-CB 4.12Å; L268-A343 VanDerWaalsContact CD2-O 3.3Å; L268-A343 WeakPolarHBondContact CD2-O 3.35Å; L268-A343 HydrophobicContact CG-CB 4.05Å; Y329-A343 HydrophobicContact CD2-CB 3.67Å; Y329-A343 HydrophobicContact CE2-CB 4.46Å; Y329-A343 HydrophobicContact CG-CB 4.3Å; T339-A343 WeakPolarHBondContact O-CB 3.46Å; T339-A343 PolarHBondContact O-N 3.37Å; C340-A343 PolarHBondContact O-N 2.75Å; S341-A343 VanDerWaalsContact C-N 3.34Å; S341-A343 PolarHBondContact O-N 2.81Å; A343-A347 WeakPolarHBondContact O-CB 3.45Å; A343-A347 PolarHBondContact O-N 3.37Å
344R97.9Very high94.2Very high108 Ų10838.4 Ų38.441%0.40821%0.213SC..Hα-helixtrans-63.9-46.6177.4-174-166.9-53.5146.79.7112C340 S341 A347 G348C340-R344 WeakPolarHBondContact O-CB 3.44Å; C340-R344 PolarHBondContact O-N 2.84Å; S341-R344 WeakPolarHBondContact O-CB 3.47Å; S341-R344 PolarHBondContact O-N 3.22Å; S341-R344 VanDerWaalsContact O-N 3.15Å; R344-A347 PolarHBondContact O-N 3.05Å; R344-G348 PolarHBondContact O-N 3.1Å
345D98.1Very high94.8Very high85 Ų8539.6 Ų39.646%0.45522%0.221SC..Hα-helixtrans-64.3-47.3-176.7-64.4-17.7000110.3S341 A347 G348 E349 A474S341-D345 WeakPolarHBondContact O-CB 3.4Å; S341-D345 PolarHBondContact O-N 3.3Å; D345-A347 PolarHBondContact O-N 3.41Å; D345-G348 PolarHBondContact O-N 3.02Å; D345-E349 WeakPolarHBondContact O-CG 3.41Å; D345-E349 PolarHBondContact O-N 3.47Å; D345-A474 HydrophobicContact CB-CB 3.95Å
346L98.6Very high95.4Very high0 Ų042.1 Ų42.10%023%0.232CC..Hα-helixtrans-61.2-44.8175179.461.8000111.7L268 S275 A278 R342 G348 E349 I350 L472 A474 L475 I478L268-L346 HydrophobicContact CD1-CD2 4.48Å; S275-L346 WeakPolarHBondContact OG-CD2 3.42Å; A278-L346 HydrophobicContact CB-CD2 4.31Å; R342-L346 WeakPolarHBondContact O-CB 3.4Å; R342-L346 PolarHBondContact O-N 2.87Å; L346-G348 VanDerWaalsContact C-N 3.26Å; L346-G348 PolarHBondContact O-N 2.92Å; L346-E349 PolarHBondContact O-N 3.19Å; L346-I350 HydrophobicContact CD1-CG2 3.97Å; L346-I350 WeakPolarHBondContact O-CG1 3.44Å; L346-I350 PolarHBondContact O-N 2.82Å; L346-L472 HydrophobicContact CD1-CD1 4.42Å; L346-A474 HydrophobicContact CB-CB 4.12Å; L346-L475 HydrophobicContact CD1-CD2 3.69Å; L346-L475 HydrophobicContact CD1-CG 4.14Å; L346-L475 HydrophobicContact CD2-CD2 4.01Å; L346-L475 HydrophobicContact CG-CD2 4.49Å; L346-I478 HydrophobicContact CB-CD1 4.21Å; L346-I478 HydrophobicContact CD2-CD1 3.92Å
347A98.5Very high95.8Very high0 Ų042.2 Ų42.20%023%0.231CC..Hα-helixtrans-60-37.7178.500000112.3L268 A343 R344 D345 I350 G351 S352 H354L268-A347 HydrophobicContact CD2-CB 4.14Å; A343-A347 WeakPolarHBondContact O-CB 3.45Å; A343-A347 PolarHBondContact O-N 3.37Å; R344-A347 PolarHBondContact O-N 3.05Å; D345-A347 PolarHBondContact O-N 3.41Å; A347-I350 WeakPolarHBondContact O-CG1 3.07Å; A347-G351 PolarHBondContact O-N 3.38Å; A347-S352 WeakPolarHBondContact CB-OG 3.34Å; A347-S352 PolarHBondContact O-N 2.87Å; A347-S352 PolarHBondContact O-OG 3.47Å; A347-H354 HydrophobicContact CB-CB 3.8Å; A347-H354 WeakPolarHBondContact CB-ND1 3.32Å
348G98.3Very high96.2Very high54 Ų5440.7 Ų40.756%0.55723%0.226SC*.Hα-helixtrans-69.3-41.7173.800000113R344 D345 L346 G351R344-G348 PolarHBondContact O-N 3.1Å; D345-G348 PolarHBondContact O-N 3.02Å; L346-G348 VanDerWaalsContact C-N 3.26Å; L346-G348 PolarHBondContact O-N 2.92Å; G348-G351 PolarHBondContact O-N 2.98Å
349E98.2Very high96.6Very high37 Ų3735.6 Ų35.617%0.17320%0.199CC..Hα-helixtrans-64-42.6177.8-74.9-174.5161.400112.4K318 D345 L346 L472 T473 A474K318-E349 VanDerWaalsContact CD-O 3.25Å; K318-E349 WeakPolarHBondContact CD-O 3.4Å; K318-E349 WeakPolarHBondContact CE-O 3.37Å; K318-E349 PolarHBondContact NZ-O 3.05Å; D345-E349 WeakPolarHBondContact O-CG 3.41Å; D345-E349 PolarHBondContact O-N 3.47Å; L346-E349 PolarHBondContact O-N 3.19Å; E349-L472 HydrophobicContact CB-CD2 3.79Å; E349-L472 WeakPolarHBondContact OE2-CA 3.29Å; E349-T473 WeakPolarHBondContact OE1-CA 3.34Å; E349-T473 WeakPolarHBondContact OE1-CB 3.22Å; E349-T473 PolarHBondContact OE1-N 3.34Å; E349-T473 PolarHBondContact OE1-OG1 3.09Å; E349-T473 PolarHBondContact OE2-N 3.18Å; E349-A474 PolarHBondContact OE1-N 3.44Å; E349-A474 VanDerWaalsContact OE1-N 3.08Å; E349-A474 VanDerWaalsContact OE2-CB 3.28Å; E349-A474 WeakPolarHBondContact OE2-CB 3.27Å; E349-A474 PolarHBondContact OE2-N 2.91Å
350I98.3Very high96.9Very high0 Ų036 Ų360%020%0.201CC..Hα-helixtrans-80.4-16.9178.270.5-174.4000113.4A278 H282 K318 C321 F325 L346 A347 L472A278-I350 HydrophobicContact CB-CD1 3.88Å; H282-I350 HydrophobicContact CB-CB 4.18Å; H282-I350 HydrophobicContact CB-CG2 4.03Å; H282-I350 PolarHBondContact ND1-O 3.36Å; K318-I350 WeakPolarHBondContact CA-O 3.45Å; C321-I350 VanDerWaalsContact CB-O 3.27Å; C321-I350 WeakPolarHBondContact CB-O 3.48Å; C321-I350 PolarHBondContact SG-O 3.03Å; F325-I350 HydrophobicContact CD1-CD1 4.12Å; F325-I350 HydrophobicContact CE1-CD1 3.82Å; L346-I350 HydrophobicContact CD1-CG2 3.97Å; L346-I350 WeakPolarHBondContact O-CG1 3.44Å; L346-I350 PolarHBondContact O-N 2.82Å; A347-I350 WeakPolarHBondContact O-CG1 3.07Å; I350-L472 HydrophobicContact CG2-CD1 3.9Å; I350-L472 HydrophobicContact CG2-CD2 3.9Å
351G98.1Very high97Very high16 Ų1641.4 Ų41.417%0.16523%0.233CC..THydrogen-bonded Turntrans86.116.1179.200000116.1A322 A347 G348A322-G351 WeakPolarHBondContact CA-O 3.48Å; A322-G351 WeakPolarHBondContact CB-O 3.08Å; A322-G351 PolarHBondContact N-O 3.49Å; A347-G351 PolarHBondContact O-N 3.38Å; G348-G351 PolarHBondContact O-N 2.98Å
352S98.3Very high97.1Very high12 Ų1242 Ų428%0.08424%0.241CC..  trans-69.5153.7-17970.20000112.7T327 A347 H354T327-S352 WeakPolarHBondContact CG2-OG 3.5Å; T327-S352 PolarHBondContact OG1-OG 2.84Å; A347-S352 WeakPolarHBondContact CB-OG 3.34Å; A347-S352 PolarHBondContact O-N 2.87Å; A347-S352 PolarHBondContact O-OG 3.47Å; S352-H354 PolarHBondContact O-N 3.5Å; S352-H354 VanDerWaalsContact O-N 3.11Å
353T97.6Very high97.1Very high48 Ų4840.5 Ų40.529%0.29424%0.236SC..EExtended strand (participates in β ladder)trans-69.7106.4166.4-62.20000108.8A322 F325 T326 T327 R416A322-T353 PolarHBondContact O-OG1 2.82Å; F325-T353 PolarHBondContact O-N 3.24Å; T326-T353 CarbonylContact C-O 3.56Å; T326-T353 VanDerWaalsContact CA-O 3.28Å; T326-T353 WeakPolarHBondContact CA-O 3.5Å; T326-T353 HydrophobicContact CG2-CG2 4.49Å; T327-T353 PolarHBondContact N-O 2.88Å; T353-R416 PolarHBondContact OG1-NH1 3.02Å
354H97.9Very high97Very high54 Ų5445.3 Ų45.325%0.2526%0.257CS..EExtended strand (participates in β ladder)trans-96.6133.1-174.9-166.261.5000112.9T327 A347 S352T327-H354 CarbonylContact O-C 3.53Å; T327-H354 WeakPolarHBondContact O-CA 3.11Å; T327-H354 PolarHBondContact OG1-ND1 2.9Å; A347-H354 HydrophobicContact CB-CB 3.8Å; A347-H354 WeakPolarHBondContact CB-ND1 3.32Å; S352-H354 PolarHBondContact O-N 3.5Å; S352-H354 VanDerWaalsContact O-N 3.11Å
355V96Very high97Very high34 Ų3442 Ų4221%0.20626%0.257CS..EExtended strand (participates in β ladder)trans-120.1135.9175-172.80000109.1T326 T327 C328 Y329 I357 F408T326-V355 HydrophobicContact CG2-CG2 4.23Å; T327-V355 PolarHBondContact O-N 3.48Å; C328-V355 CarbonylContact C-O 3.54Å; C328-V355 VanDerWaalsContact CA-O 3.29Å; C328-V355 WeakPolarHBondContact CA-O 3.27Å; C328-V355 HydrophobicContact CB-CB 4.5Å; Y329-V355 PolarHBondContact N-O 3.34Å; V355-I357 HydrophobicContact CG1-CG2 3.81Å; V355-F408 HydrophobicContact CG1-CE1 3.89Å; V355-F408 HydrophobicContact CG1-CZ 4.32Å
356N95.8Very high97Very high83 Ų8341.9 Ų41.944%0.44426%0.255SS..EExtended strand (participates in β ladder)trans-117.4123.3172.2-174.5-1.9000109.1Y329 C340Y329-N356 WeakPolarHBondContact CD1-OD1 3.27Å; Y329-N356 WeakPolarHBondContact O-CA 3.35Å; C340-N356 PolarHBondContact SG-ND2 3.36Å
357I94.7Very high96.9Very high28 Ų2842.7 Ų42.714%0.14426%0.26CS..EExtended strand (participates in β ladder)trans-128.9148.8178.866.1-178000111Y329 M330 G331 V355 L404 F408Y329-I357 PolarHBondContact O-N 3.21Å; M330-I357 CarbonylContact C-O 3.48Å; M330-I357 WeakPolarHBondContact CA-O 3.22Å; M330-I357 HydrophobicContact CB-CD1 4.37Å; M330-I357 HydrophobicContact CB-CG1 3.99Å; M330-I357 HydrophobicContact CG-CD1 3.71Å; M330-I357 HydrophobicContact CG-CG1 3.7Å; M330-I357 HydrophobicContact SD-CD1 4.07Å; G331-I357 PolarHBondContact N-O 3.42Å; V355-I357 HydrophobicContact CG1-CG2 3.81Å; I357-L404 HydrophobicContact CD1-CB 4.02Å; I357-L404 HydrophobicContact CD1-CD1 3.82Å; I357-L404 HydrophobicContact CD1-CG 4.4Å; I357-F408 HydrophobicContact CD1-CD2 4.48Å; I357-F408 HydrophobicContact CD1-CE2 3.92Å; I357-F408 HydrophobicContact CG2-CE2 4.18Å; I357-F408 HydrophobicContact CG2-CZ 3.83Å
358N95.1Very high96.8Very high93 Ų9343.8 Ų43.850%0.49727%0.271SS..EExtended strand (participates in β ladder)trans-102.1131.6170.1177.5-66.2000109.5G331 D360G331-N358 WeakPolarHBondContact O-CA 3.32Å; N358-D360 PolarHBondContact ND2-OD2 2.91Å; N358-D360 WeakPolarHBondContact OD1-CB 3.46Å; N358-D360 VanDerWaalsContact OD1-CG 3.25Å; N358-D360 PolarHBondContact OD1-N 3.46Å; N358-D360 PolarHBondContact OD1-OD2 3.29Å; N358-D360 VanDerWaalsContact OD1-OD2 3.12Å
359I96.6Very high96.8Very high1 Ų146.9 Ų46.91%0.00527%0.274CS..  trans-94-7-175.470.4176.7000114.2M330 G331 V361 A362 V363 Q397 V400 R401 L404M330-I359 HydrophobicContact CB-CG2 3.93Å; G331-I359 WeakPolarHBondContact O-CG1 3.31Å; G331-I359 PolarHBondContact O-N 3.21Å; I359-V361 VanDerWaalsContact C-N 3.28Å; I359-V361 PolarHBondContact O-N 3.14Å; I359-A362 PolarHBondContact O-N 3.47Å; I359-A362 VanDerWaalsContact O-N 3.07Å; I359-V363 HydrophobicContact CB-CG2 4.42Å; I359-V363 HydrophobicContact CD1-CG2 4.11Å; I359-V363 HydrophobicContact CG1-CG2 4Å; I359-V363 WeakPolarHBondContact O-CG2 3.43Å; I359-V363 PolarHBondContact O-N 3.04Å; I359-Q397 HydrophobicContact CD1-CB 3.99Å; I359-Q397 HydrophobicContact CD1-CG 4.34Å; I359-V400 HydrophobicContact CB-CG1 4.04Å; I359-V400 HydrophobicContact CG2-CG1 4.43Å; I359-R401 HydrophobicContact CD1-CG 3.96Å; I359-R401 HydrophobicContact CG2-CG 4.23Å; I359-L404 HydrophobicContact CB-CD1 4.41Å; I359-L404 HydrophobicContact CG2-CD1 3.69Å
360D95Very high96.7Very high19 Ų1950.1 Ų50.110%0.10229%0.287CS..Hα-helixtrans-62.8-35.4-166.9-60.9-34.7000112.2S332 E333 N358 A362 V363 K364S332-D360 VanDerWaalsContact CA-OD1 3.27Å; S332-D360 WeakPolarHBondContact CA-OD1 3.46Å; S332-D360 WeakPolarHBondContact CB-OD1 3.31Å; E333-D360 VanDerWaalsContact N-CG 3.33Å; E333-D360 PolarHBondContact N-OD1 3.44Å; E333-D360 PolarHBondContact N-OD2 3.29Å; N358-D360 PolarHBondContact ND2-OD2 2.91Å; N358-D360 WeakPolarHBondContact OD1-CB 3.46Å; N358-D360 VanDerWaalsContact OD1-CG 3.25Å; N358-D360 PolarHBondContact OD1-N 3.46Å; N358-D360 PolarHBondContact OD1-OD2 3.29Å; N358-D360 VanDerWaalsContact OD1-OD2 3.12Å; D360-A362 PolarHBondContact O-N 3.17Å; D360-V363 PolarHBondContact O-N 3.32Å; D360-K364 VanDerWaalsContact O-CB 3.22Å; D360-K364 WeakPolarHBondContact O-CB 3.4Å; D360-K364 VanDerWaalsContact O-CG 3.26Å; D360-K364 WeakPolarHBondContact O-CG 3.39Å; D360-K364 PolarHBondContact O-N 3.24Å
361V96.4Very high96.7Very high122 Ų12251.6 Ų51.674%0.73930%0.298SS*.Hα-helixtrans-61.6-45.4176.8177.90000110.8I359 G365I359-V361 VanDerWaalsContact C-N 3.28Å; I359-V361 PolarHBondContact O-N 3.14Å; V361-G365 PolarHBondContact O-N 3.24Å
362A96.7Very high96.7Very high43 Ų4357 Ų5736%0.35533%0.327SS..Hα-helixtrans-68.6-42.3178.600000111.5I359 D360 G365 I366 V400I359-A362 PolarHBondContact O-N 3.47Å; I359-A362 VanDerWaalsContact O-N 3.07Å; D360-A362 PolarHBondContact O-N 3.17Å; A362-G365 PolarHBondContact O-N 3.37Å; A362-I366 WeakPolarHBondContact O-CG1 3.42Å; A362-I366 PolarHBondContact O-N 3.05Å; A362-V400 HydrophobicContact CB-CG1 3.82Å
363V96.3Very high96.7Very high13 Ų1362.1 Ų62.18%0.07936%0.358CS..Hα-helixtrans-61.6-49.9176.7173.30000110.7I359 D360 G365 I366 L367 V396 Q397 V400I359-V363 HydrophobicContact CB-CG2 4.42Å; I359-V363 HydrophobicContact CD1-CG2 4.11Å; I359-V363 HydrophobicContact CG1-CG2 4Å; I359-V363 WeakPolarHBondContact O-CG2 3.43Å; I359-V363 PolarHBondContact O-N 3.04Å; D360-V363 PolarHBondContact O-N 3.32Å; V363-G365 VanDerWaalsContact C-N 3.29Å; V363-G365 PolarHBondContact O-N 2.95Å; V363-I366 PolarHBondContact O-N 3.13Å; V363-I366 VanDerWaalsContact O-N 3.17Å; V363-L367 HydrophobicContact CG1-CD1 3.95Å; V363-L367 HydrophobicContact CG1-CG 4.36Å; V363-L367 WeakPolarHBondContact O-CG 3.42Å; V363-L367 PolarHBondContact O-N 2.82Å; V363-V396 HydrophobicContact CG1-CG1 4.25Å; V363-Q397 HydrophobicContact CG1-CG 4.27Å; V363-Q397 HydrophobicContact CG2-CG 4.04Å; V363-V400 HydrophobicContact CG2-CB 4.29Å; V363-V400 HydrophobicContact CG2-CG1 4.34Å; V363-V400 HydrophobicContact CG2-CG2 4.1Å
364K95.6Very high96.7Very high101 Ų10162.8 Ų62.844%0.43936%0.362SS..Hα-helixtrans-60.9-37.8177.5-74.6170.1-179.5162.70111.7E333 D360 G368E333-K364 WeakPolarHBondContact OE2-CE 3.43Å; E333-K364 IonicContact OE2-NZ 3.1Å; E333-K364 PolarHBondContact OE2-NZ 3.4Å; D360-K364 VanDerWaalsContact O-CB 3.22Å; D360-K364 WeakPolarHBondContact O-CB 3.4Å; D360-K364 VanDerWaalsContact O-CG 3.26Å; D360-K364 WeakPolarHBondContact O-CG 3.39Å; D360-K364 PolarHBondContact O-N 3.24Å; K364-G368 PolarHBondContact O-N 2.81Å
365G97.4Very high96.6Very high40 Ų4063.6 Ų63.641%0.41239%0.385SS..Hα-helixtrans-59.3-48.2172.600000113V361 A362 V363 G368 I369V361-G365 PolarHBondContact O-N 3.24Å; A362-G365 PolarHBondContact O-N 3.37Å; V363-G365 VanDerWaalsContact C-N 3.29Å; V363-G365 PolarHBondContact O-N 2.95Å; G365-G368 PolarHBondContact O-N 3.41Å; G365-I369 WeakPolarHBondContact O-CG1 3.4Å; G365-I369 PolarHBondContact O-N 3.34Å; G365-I369 VanDerWaalsContact O-N 3.14Å
366I96.9Very high96.6Very high81 Ų8171.3 Ų71.342%0.41541%0.41SS..Hα-helixtrans-64.3-45.2178.5-68.6166.6000111.5A362 V363 G368 I369 F370 V396 V400A362-I366 WeakPolarHBondContact O-CG1 3.42Å; A362-I366 PolarHBondContact O-N 3.05Å; V363-I366 PolarHBondContact O-N 3.13Å; V363-I366 VanDerWaalsContact O-N 3.17Å; I366-G368 VanDerWaalsContact C-N 3.3Å; I366-G368 PolarHBondContact O-N 3.45Å; I366-I369 PolarHBondContact O-N 2.75Å; I366-F370 PolarHBondContact O-N 2.94Å; I366-V396 HydrophobicContact CB-CG1 4.49Å; I366-V396 HydrophobicContact CG2-CG1 4.12Å; I366-V400 HydrophobicContact CD1-CG2 3.41Å; I366-V400 VanDerWaalsContact CD1-CG2 3.41Å
367L96.3Very high96.6Very high17 Ų1773.4 Ų73.49%0.08941%0.412CS..Hα-helixtrans-66.1-34.3177.4-64178.7000111.9V363 F370 S371 W377 P378 L393V363-L367 HydrophobicContact CG1-CD1 3.95Å; V363-L367 HydrophobicContact CG1-CG 4.36Å; V363-L367 WeakPolarHBondContact O-CG 3.42Å; V363-L367 PolarHBondContact O-N 2.82Å; L367-F370 PolarHBondContact O-N 3.02Å; L367-S371 WeakPolarHBondContact O-CB 3.49Å; L367-S371 PolarHBondContact O-N 3.4Å; L367-W377 HydrophobicContact CB-CH2 3.58Å; L367-W377 HydrophobicContact CB-CZ2 3.88Å; L367-W377 HydrophobicContact CB-CZ3 4.04Å; L367-W377 HydrophobicContact CD1-CZ2 4.05Å; L367-P378 HydrophobicContact CD2-CG 4.14Å; L367-L393 HydrophobicContact CD1-CD2 3.56Å; L367-L393 HydrophobicContact CD2-CD2 3.77Å; L367-L393 HydrophobicContact CG-CD2 4.33Å
368G97.6Very high96.7Very high24 Ų2473 Ų7325%0.24741%0.411CS..Hα-helixtrans-57.2-47.4171.800000112.3K364 G365 I366 F370 S371 V372K364-G368 PolarHBondContact O-N 2.81Å; G365-G368 PolarHBondContact O-N 3.41Å; I366-G368 VanDerWaalsContact C-N 3.3Å; I366-G368 PolarHBondContact O-N 3.45Å; G368-F370 PolarHBondContact O-N 3.42Å; G368-S371 PolarHBondContact O-N 3.47Å; G368-V372 VanDerWaalsContact O-CG2 3.31Å; G368-V372 WeakPolarHBondContact O-CG2 3.29Å; G368-V372 PolarHBondContact O-N 3.27Å
369I97.6Very high96.6Very high119 Ų11972.9 Ų72.961%0.6141%0.407SS*.Hα-helixtrans-59.1-47.2176.2-64.5164.8000110.8G365 I366 S371 V372 V373G365-I369 WeakPolarHBondContact O-CG1 3.4Å; G365-I369 PolarHBondContact O-N 3.34Å; G365-I369 VanDerWaalsContact O-N 3.14Å; I366-I369 PolarHBondContact O-N 2.75Å; I369-S371 VanDerWaalsContact C-N 3.33Å; I369-S371 PolarHBondContact O-N 3.45Å; I369-V372 PolarHBondContact O-N 3.43Å; I369-V373 WeakPolarHBondContact O-CG2 3.33Å; I369-V373 PolarHBondContact O-N 3.05Å
370F97.6Very high96.3Very high104 Ų10473.7 Ų73.746%0.45641%0.411SS..Hα-helixtrans-59.9-43.7177.4178.2-93000112.1I366 L367 G368 V373 T374I366-F370 PolarHBondContact O-N 2.94Å; L367-F370 PolarHBondContact O-N 3.02Å; G368-F370 PolarHBondContact O-N 3.42Å; F370-V373 PolarHBondContact O-N 3.12Å; F370-T374 HydrophobicContact CD2-CG2 4.04Å; F370-T374 HydrophobicContact CE1-CG2 4.21Å; F370-T374 WeakPolarHBondContact CE1-OG1 3.42Å; F370-T374 HydrophobicContact CE2-CG2 3.71Å; F370-T374 HydrophobicContact CG-CG2 4.43Å; F370-T374 HydrophobicContact CZ-CG2 3.81Å; F370-T374 WeakPolarHBondContact O-CB 3.4Å; F370-T374 WeakPolarHBondContact O-CG2 3.41Å; F370-T374 PolarHBondContact O-N 3.16Å; F370-T374 PolarHBondContact O-OG1 3.21Å
371S97.1Very high96Very high32 Ų3277.4 Ų77.422%0.22443%0.427CS..Hα-helixtrans-65.6-42.6-179.8-174.80000112.3L367 G368 I369 V373 T374 G375 R376L367-S371 WeakPolarHBondContact O-CB 3.49Å; L367-S371 PolarHBondContact O-N 3.4Å; G368-S371 PolarHBondContact O-N 3.47Å; I369-S371 VanDerWaalsContact C-N 3.33Å; I369-S371 PolarHBondContact O-N 3.45Å; S371-V373 VanDerWaalsContact C-N 3.28Å; S371-V373 PolarHBondContact O-N 2.78Å; S371-T374 PolarHBondContact O-N 3.23Å; S371-G375 VanDerWaalsContact O-CA 3.29Å; S371-G375 WeakPolarHBondContact O-CA 3.37Å; S371-G375 PolarHBondContact O-N 2.91Å; S371-R376 WeakPolarHBondContact CA-O 3.37Å
372V97.8Very high95.5Very high129 Ų12973.4 Ų73.478%0.78241%0.407SS*.Hα-helixtrans-59.9-38.9176.6168.90000111.6G368 I369G368-V372 VanDerWaalsContact O-CG2 3.31Å; G368-V372 WeakPolarHBondContact O-CG2 3.29Å; G368-V372 PolarHBondContact O-N 3.27Å; I369-V372 PolarHBondContact O-N 3.43Å
373V97.7Very high95.1Very high119 Ų11976.3 Ų76.372%0.72142%0.417SS*.Hα-helixtrans-80.2-38-178.2175.80000112.6I369 F370 S371I369-V373 WeakPolarHBondContact O-CG2 3.33Å; I369-V373 PolarHBondContact O-N 3.05Å; F370-V373 PolarHBondContact O-N 3.12Å; S371-V373 VanDerWaalsContact C-N 3.28Å; S371-V373 PolarHBondContact O-N 2.78Å
374T97.6Very high94.7Very high63 Ų6378.9 Ų78.939%0.38745%0.446SS..Hα-helixtrans-102.1-14.1-170.865.30000114.4F370 S371 R376F370-T374 HydrophobicContact CD2-CG2 4.04Å; F370-T374 HydrophobicContact CE1-CG2 4.21Å; F370-T374 WeakPolarHBondContact CE1-OG1 3.42Å; F370-T374 HydrophobicContact CE2-CG2 3.71Å; F370-T374 HydrophobicContact CG-CG2 4.43Å; F370-T374 HydrophobicContact CZ-CG2 3.81Å; F370-T374 WeakPolarHBondContact O-CB 3.4Å; F370-T374 WeakPolarHBondContact O-CG2 3.41Å; F370-T374 PolarHBondContact O-N 3.16Å; F370-T374 PolarHBondContact O-OG1 3.21Å; S371-T374 PolarHBondContact O-N 3.23Å; T374-R376 PolarHBondContact O-N 2.93Å; T374-R376 PolarHBondContact OG1-N 3.39Å; T374-R376 PolarHBondContact OG1-O 3.33Å
375G96.8Very high94.6Very high70 Ų7074.3 Ų74.372%0.72243%0.428SS*.SBendtrans67.714-17200000114S371S371-G375 VanDerWaalsContact O-CA 3.29Å; S371-G375 WeakPolarHBondContact O-CA 3.37Å; S371-G375 PolarHBondContact O-N 2.91Å
376R96.2Very high94.4Very high197 Ų19775 Ų7574%0.74343%0.426SS*.  trans-127.8139.1-177.9-65.2-169.4178.9-151.7-0.3111.9S371 T374S371-R376 WeakPolarHBondContact CA-O 3.37Å; T374-R376 PolarHBondContact O-N 2.93Å; T374-R376 PolarHBondContact OG1-N 3.39Å; T374-R376 PolarHBondContact OG1-O 3.33Å
377W96.1Very high94.1Very high127 Ų12777.1 Ų77.148%0.48144%0.438SS..  trans-108.2114.6171.9-169.2-85.2000110L367L367-W377 HydrophobicContact CB-CH2 3.58Å; L367-W377 HydrophobicContact CB-CZ2 3.88Å; L367-W377 HydrophobicContact CB-CZ3 4.04Å; L367-W377 HydrophobicContact CD1-CZ2 4.05Å
378P95.7Very high94Very high18 Ų1886.4 Ų86.412%0.11747%0.472CS..  trans-67.2146.6178.926.6-32.2000111.5L367 E389 L393L367-P378 HydrophobicContact CD2-CG 4.14Å; P378-E389 HydrophobicContact CB-CB 4.14Å; P378-E389 HydrophobicContact CB-CG 4.14Å; P378-L393 HydrophobicContact CB-CD2 4.34Å; P378-L393 HydrophobicContact CB-CG 4.35Å; P378-L393 HydrophobicContact CG-CD2 3.93Å; P378-L393 HydrophobicContact CG-CG 4.46Å
379Q93.3Very high93.9Very high91 Ų9188.1 Ų88.143%0.42547%0.474SS..  trans-118.2149.7-178.7-65.1-179.4-14.500112.4N383 G385 E389Q379-N383 HydrophobicContact CB-CB 4.44Å; Q379-N383 PolarHBondContact OE1-O 2.92Å; Q379-G385 WeakPolarHBondContact O-CA 3.33Å; Q379-E389 PolarHBondContact N-OE2 3.04Å; Q379-E389 WeakPolarHBondContact O-CB 3.46Å
380F91Very high93.7Very high19 Ų1983.1 Ų83.18%0.08345%0.448CS..  trans-68.1157.3169-74.3-74.3000110.6A382 N383 G384 G385 L393 Q394 L487 P489F380-A382 VanDerWaalsContact C-N 3.26Å; F380-A382 PolarHBondContact O-N 3.05Å; F380-N383 CarbonylContact O-C 3.52Å; F380-N383 WeakPolarHBondContact O-CA 3.46Å; F380-N383 PolarHBondContact O-N 2.97Å; F380-G384 PolarHBondContact O-N 2.8Å; F380-G385 PolarHBondContact O-N 3.48Å; F380-L393 HydrophobicContact CB-CD1 4.44Å; F380-L393 HydrophobicContact CD1-CB 4.08Å; F380-L393 HydrophobicContact CD1-CD1 3.89Å; F380-L393 HydrophobicContact CD2-CD1 3.89Å; F380-L393 HydrophobicContact CE1-CB 3.58Å; F380-L393 HydrophobicContact CE1-CD1 4.08Å; F380-L393 HydrophobicContact CE1-CG 4.47Å; F380-L393 HydrophobicContact CE2-CD1 4.07Å; F380-L393 HydrophobicContact CG-CD1 3.79Å; F380-L393 HydrophobicContact CZ-CB 3.83Å; F380-L393 HydrophobicContact CZ-CD1 4.16Å; F380-Q394 HydrophobicContact CE1-CG 4.49Å; F380-L487 VanDerWaalsContact CE1-O 3.29Å; F380-L487 WeakPolarHBondContact CE1-O 3.45Å; F380-P489 HydrophobicContact CB-CG 4.02Å; F380-P489 HydrophobicContact CD2-CG 3.69Å; F380-P489 HydrophobicContact CE2-CG 4.25Å; F380-P489 VanDerWaalsContact CG-CD 3.46Å; F380-P489 HydrophobicContact CG-CG 3.84Å
381H88.8Confident93.4Very high96 Ų9682.7 Ų82.744%0.44445%0.45SS..G310 helixtrans-59.3-38.5178.7-175.5-108000112.1N383 G384 N390H381-N383 PolarHBondContact O-N 2.97Å; H381-N383 VanDerWaalsContact O-N 3.11Å; H381-G384 PolarHBondContact O-N 3.3Å; H381-N390 HydrophobicContact CB-CB 4.1Å; H381-N390 PolarHBondContact N-OD1 2.5Å
382A85.5Confident93.4Very high39 Ų3983.3 Ų83.332%0.32246%0.457SS..G310 helixtrans-56.8-25.6173.900000113.6F380 P489F380-A382 VanDerWaalsContact C-N 3.26Å; F380-A382 PolarHBondContact O-N 3.05Å; A382-P489 HydrophobicContact CB-CB 4.37Å
383N87.8Confident93.3Very high103 Ų10377.6 Ų77.655%0.55142%0.422SS*.G310 helixtrans-104.713.1-178.4-60.7-13.7000112.7Q379 F380 H381Q379-N383 HydrophobicContact CB-CB 4.44Å; Q379-N383 PolarHBondContact OE1-O 2.92Å; F380-N383 CarbonylContact O-C 3.52Å; F380-N383 WeakPolarHBondContact O-CA 3.46Å; F380-N383 PolarHBondContact O-N 2.97Å; H381-N383 PolarHBondContact O-N 2.97Å; H381-N383 VanDerWaalsContact O-N 3.11Å
384G88.9Confident93.1Very high68 Ų6873.4 Ų73.470%0.70140%0.395SS*.THydrogen-bonded Turntrans91.57.5178.600000115.6F380 H381F380-G384 PolarHBondContact O-N 2.8Å; H381-G384 PolarHBondContact O-N 3.3Å
385G91.9Very high93Very high5 Ų571.9 Ų71.95%0.05238%0.384CS..  trans-72.7155.4175.800000113.7Q379 F380Q379-G385 WeakPolarHBondContact O-CA 3.33Å; F380-G385 PolarHBondContact O-N 3.48Å
386S94.9Very high93Very high54 Ų5470 Ų7038%0.37836%0.359SS..  trans-71.4162.1176.467.10000112.9R388 E389 N390S386-R388 PolarHBondContact O-N 2.88Å; S386-R388 VanDerWaalsContact O-N 3.09Å; S386-E389 VanDerWaalsContact CB-OE1 3.26Å; S386-E389 WeakPolarHBondContact CB-OE1 3.46Å; S386-E389 PolarHBondContact N-OE1 3.02Å; S386-E389 PolarHBondContact O-N 3.39Å; S386-E389 WeakPolarHBondContact OG-CG 3.37Å; S386-E389 PolarHBondContact OG-N 3.01Å; S386-E389 PolarHBondContact OG-OE1 3.08Å; S386-N390 WeakPolarHBondContact O-CB 3.2Å; S386-N390 PolarHBondContact O-N 2.84Å
387N90.6Very high93Very high125 Ų12560.8 Ų60.867%0.66832%0.324SS*.Hα-helixtrans-52.8-34.2174.2-68.7-7.8000112.9L391N387-L391 VanDerWaalsContact O-CB 3.29Å; N387-L391 WeakPolarHBondContact O-CB 3.31Å; N387-L391 PolarHBondContact O-N 3.19Å; N387-L391 VanDerWaalsContact O-N 3.08Å
388R94.6Very high93Very high212 Ų21255 Ų5580%0.830%0.303SS*.Hα-helixtrans-70-44.4178.4-179.1-178.9-71.2-173.5-0.9111.6S386 A392S386-R388 PolarHBondContact O-N 2.88Å; S386-R388 VanDerWaalsContact O-N 3.09Å; R388-A392 VanDerWaalsContact O-CB 3.31Å; R388-A392 WeakPolarHBondContact O-CB 3.19Å; R388-A392 PolarHBondContact O-N 3.43Å
389E95.4Very high93.2Very high61 Ų6158.8 Ų58.829%0.28532%0.315SS..Hα-helixtrans-65.2-46.9178.4-69.3164.6-96.200110.8P378 Q379 S386 L391 A392 L393P378-E389 HydrophobicContact CB-CB 4.14Å; P378-E389 HydrophobicContact CB-CG 4.14Å; Q379-E389 PolarHBondContact N-OE2 3.04Å; Q379-E389 WeakPolarHBondContact O-CB 3.46Å; S386-E389 VanDerWaalsContact CB-OE1 3.26Å; S386-E389 WeakPolarHBondContact CB-OE1 3.46Å; S386-E389 PolarHBondContact N-OE1 3.02Å; S386-E389 PolarHBondContact O-N 3.39Å; S386-E389 WeakPolarHBondContact OG-CG 3.37Å; S386-E389 PolarHBondContact OG-N 3.01Å; S386-E389 PolarHBondContact OG-OE1 3.08Å; E389-L391 PolarHBondContact O-N 2.88Å; E389-A392 WeakPolarHBondContact O-CB 3.18Å; E389-A392 PolarHBondContact O-N 2.73Å; E389-A392 VanDerWaalsContact O-N 3.1Å; E389-L393 WeakPolarHBondContact O-CG 3.14Å; E389-L393 PolarHBondContact O-N 2.79Å
390N92Very high93.4Very high13 Ų1354.9 Ų54.97%0.0730%0.298CS..Hα-helixtrans-55.7-51.7177.8-171.369.3000111.7H381 S386 A392 L393 Q394 E488H381-N390 HydrophobicContact CB-CB 4.1Å; H381-N390 PolarHBondContact N-OD1 2.5Å; S386-N390 WeakPolarHBondContact O-CB 3.2Å; S386-N390 PolarHBondContact O-N 2.84Å; N390-A392 VanDerWaalsContact C-N 3.32Å; N390-A392 PolarHBondContact O-N 3.41Å; N390-L393 PolarHBondContact O-N 2.97Å; N390-Q394 PolarHBondContact ND2-NE2 3.44Å; N390-Q394 WeakPolarHBondContact O-CG 3.31Å; N390-Q394 PolarHBondContact O-N 3.07Å; N390-Q394 VanDerWaalsContact O-N 3.1Å; N390-E488 PolarHBondContact ND2-OE1 3.15Å
391L92.8Very high93.7Very high96 Ų9655.7 Ų55.750%0.50330%0.3SS..Hα-helixtrans-62.3-37.9176.4-179.660.6000112.2N387 E389 N395N387-L391 VanDerWaalsContact O-CB 3.29Å; N387-L391 WeakPolarHBondContact O-CB 3.31Å; N387-L391 PolarHBondContact O-N 3.19Å; N387-L391 VanDerWaalsContact O-N 3.08Å; E389-L391 PolarHBondContact O-N 2.88Å; L391-N395 VanDerWaalsContact O-CB 3.31Å; L391-N395 WeakPolarHBondContact O-CB 3.49Å; L391-N395 PolarHBondContact O-N 2.88Å; L391-N395 PolarHBondContact O-ND2 2.97Å
392A95.6Very high94.2Very high45 Ų4553 Ų5337%0.37229%0.289SS..Hα-helixtrans-64.4-43177.400000112R388 E389 N390 N395 V396R388-A392 VanDerWaalsContact O-CB 3.31Å; R388-A392 WeakPolarHBondContact O-CB 3.19Å; R388-A392 PolarHBondContact O-N 3.43Å; E389-A392 WeakPolarHBondContact O-CB 3.18Å; E389-A392 PolarHBondContact O-N 2.73Å; E389-A392 VanDerWaalsContact O-N 3.1Å; N390-A392 VanDerWaalsContact C-N 3.32Å; N390-A392 PolarHBondContact O-N 3.41Å; A392-N395 PolarHBondContact O-N 2.9Å; A392-V396 WeakPolarHBondContact O-CG2 3.06Å; A392-V396 PolarHBondContact O-N 2.97Å
393L95.3Very high94.8Very high8 Ų855.5 Ų55.54%0.04230%0.299CS..Hα-helixtrans-63.3-44.2177.6-72.4172.7000112.3L367 P378 F380 E389 N390 V396 Q397L367-L393 HydrophobicContact CD1-CD2 3.56Å; L367-L393 HydrophobicContact CD2-CD2 3.77Å; L367-L393 HydrophobicContact CG-CD2 4.33Å; P378-L393 HydrophobicContact CB-CD2 4.34Å; P378-L393 HydrophobicContact CB-CG 4.35Å; P378-L393 HydrophobicContact CG-CD2 3.93Å; P378-L393 HydrophobicContact CG-CG 4.46Å; F380-L393 HydrophobicContact CB-CD1 4.44Å; F380-L393 HydrophobicContact CD1-CB 4.08Å; F380-L393 HydrophobicContact CD1-CD1 3.89Å; F380-L393 HydrophobicContact CD2-CD1 3.89Å; F380-L393 HydrophobicContact CE1-CB 3.58Å; F380-L393 HydrophobicContact CE1-CD1 4.08Å; F380-L393 HydrophobicContact CE1-CG 4.47Å; F380-L393 HydrophobicContact CE2-CD1 4.07Å; F380-L393 HydrophobicContact CG-CD1 3.79Å; F380-L393 HydrophobicContact CZ-CB 3.83Å; F380-L393 HydrophobicContact CZ-CD1 4.16Å; E389-L393 WeakPolarHBondContact O-CG 3.14Å; E389-L393 PolarHBondContact O-N 2.79Å; N390-L393 PolarHBondContact O-N 2.97Å; L393-V396 PolarHBondContact O-N 3.33Å; L393-Q397 WeakPolarHBondContact O-CG 3.46Å; L393-Q397 PolarHBondContact O-N 3.16Å; L393-Q397 PolarHBondContact O-NE2 2.76Å
394Q93.9Very high95.3Very high32 Ų3252.1 Ų52.115%0.1528%0.281CS..Hα-helixtrans-60.4-45.8173.7-66.3-176.846.900111.4F380 N390 V396 Q397 A398 L487 E488F380-Q394 HydrophobicContact CE1-CG 4.49Å; N390-Q394 PolarHBondContact ND2-NE2 3.44Å; N390-Q394 WeakPolarHBondContact O-CG 3.31Å; N390-Q394 PolarHBondContact O-N 3.07Å; N390-Q394 VanDerWaalsContact O-N 3.1Å; Q394-V396 VanDerWaalsContact C-N 3.34Å; Q394-V396 PolarHBondContact O-N 3.42Å; Q394-Q397 PolarHBondContact O-N 3.21Å; Q394-A398 WeakPolarHBondContact O-CB 3.49Å; Q394-A398 PolarHBondContact O-N 3.26Å; Q394-L487 HydrophobicContact CB-CB 4.09Å; Q394-L487 HydrophobicContact CB-CD1 4.21Å; Q394-L487 HydrophobicContact CG-CB 3.76Å; Q394-E488 HydrophobicContact CG-CG 4.18Å; Q394-E488 PolarHBondContact NE2-OE1 3.24Å
395N96.1Very high95.7Very high30 Ų3049 Ų4916%0.1625%0.248CC..Hα-helixtrans-63.1-36.8179.1-72.2-29.2000112.8L391 A392 A398 R399 T439L391-N395 VanDerWaalsContact O-CB 3.31Å; L391-N395 WeakPolarHBondContact O-CB 3.49Å; L391-N395 PolarHBondContact O-N 2.88Å; L391-N395 PolarHBondContact O-ND2 2.97Å; A392-N395 PolarHBondContact O-N 2.9Å; N395-A398 PolarHBondContact O-N 2.84Å; N395-R399 WeakPolarHBondContact O-CG 3.5Å; N395-R399 PolarHBondContact O-N 2.95Å; N395-T439 HydrophobicContact CB-CG2 3.91Å; N395-T439 WeakPolarHBondContact OD1-CG2 3.47Å; N395-T439 PolarHBondContact OD1-OG1 3.28Å
396V97.3Very high96.1Very high30 Ų3051.4 Ų51.418%0.18226%0.256CS..Hα-helixtrans-62.9-48.7176168.80000110V363 I366 A392 L393 Q394 A398 R399 V400V363-V396 HydrophobicContact CG1-CG1 4.25Å; I366-V396 HydrophobicContact CB-CG1 4.49Å; I366-V396 HydrophobicContact CG2-CG1 4.12Å; A392-V396 WeakPolarHBondContact O-CG2 3.06Å; A392-V396 PolarHBondContact O-N 2.97Å; L393-V396 PolarHBondContact O-N 3.33Å; Q394-V396 VanDerWaalsContact C-N 3.34Å; Q394-V396 PolarHBondContact O-N 3.42Å; V396-A398 VanDerWaalsContact C-N 3.32Å; V396-A398 PolarHBondContact O-N 3.38Å; V396-R399 PolarHBondContact O-N 3.36Å; V396-V400 HydrophobicContact CG1-CG2 4.34Å; V396-V400 VanDerWaalsContact O-CG2 3.31Å; V396-V400 WeakPolarHBondContact O-CG2 3.32Å; V396-V400 PolarHBondContact O-N 3.14Å
397Q96.5Very high96.2Very high4 Ų452.7 Ų52.72%0.01926%0.259CS..Hα-helixtrans-57.3-46175.9-67.1173.477.100111.4S332 N334 I359 V363 L393 Q394 R399 V400 R401 L487S332-Q397 PolarHBondContact OG-OE1 3.33Å; N334-Q397 PolarHBondContact ND2-OE1 2.81Å; I359-Q397 HydrophobicContact CD1-CB 3.99Å; I359-Q397 HydrophobicContact CD1-CG 4.34Å; V363-Q397 HydrophobicContact CG1-CG 4.27Å; V363-Q397 HydrophobicContact CG2-CG 4.04Å; L393-Q397 WeakPolarHBondContact O-CG 3.46Å; L393-Q397 PolarHBondContact O-N 3.16Å; L393-Q397 PolarHBondContact O-NE2 2.76Å; Q394-Q397 PolarHBondContact O-N 3.21Å; Q397-R399 PolarHBondContact O-N 2.77Å; Q397-V400 PolarHBondContact O-N 3.33Å; Q397-R401 WeakPolarHBondContact O-CG 3.33Å; Q397-R401 PolarHBondContact O-N 3Å; Q397-L487 HydrophobicContact CB-CD2 4.45Å; Q397-L487 PolarHBondContact NE2-O 2.96Å
398A96Very high96.6Very high6 Ų649.5 Ų49.55%0.0524%0.239CC..Hα-helixtrans-60.2-41.8179.700000112.7Q394 N395 V396 M402 T439 D442Q394-A398 WeakPolarHBondContact O-CB 3.49Å; Q394-A398 PolarHBondContact O-N 3.26Å; N395-A398 PolarHBondContact O-N 2.84Å; V396-A398 VanDerWaalsContact C-N 3.32Å; V396-A398 PolarHBondContact O-N 3.38Å; A398-M402 PolarHBondContact O-N 2.87Å; A398-T439 HydrophobicContact CB-CG2 4.28Å; A398-D442 HydrophobicContact CB-CB 3.59Å; A398-D442 WeakPolarHBondContact O-CB 3.13Å
399R98.1Very high96.8Very high97 Ų9739.5 Ų39.537%0.36620%0.202SC..Hα-helixtrans-74.6-34.7178.3-66.4-171.5-169.3103.65.2113.6N395 V396 Q397 R401 M402 V403 T439 K440N395-R399 WeakPolarHBondContact O-CG 3.5Å; N395-R399 PolarHBondContact O-N 2.95Å; V396-R399 PolarHBondContact O-N 3.36Å; Q397-R399 PolarHBondContact O-N 2.77Å; R399-R401 VanDerWaalsContact C-N 3.26Å; R399-R401 PolarHBondContact O-N 3.45Å; R399-M402 WeakPolarHBondContact O-CB 3.27Å; R399-M402 PolarHBondContact O-N 3.27Å; R399-M402 VanDerWaalsContact O-N 3.13Å; R399-V403 PolarHBondContact O-N 3.4Å; R399-T439 HydrophobicContact CG-CG2 4.38Å; R399-K440 PolarHBondContact NE-O 3.39Å; R399-K440 PolarHBondContact NH2-O 2.95Å
400V98Very high96.9Very high9 Ų942.8 Ų42.86%0.05522%0.217CC..Hα-helixtrans-60.1-40.5174.4168.10000110.6I359 A362 V363 I366 V396 Q397 M402 V403 L404I359-V400 HydrophobicContact CB-CG1 4.04Å; I359-V400 HydrophobicContact CG2-CG1 4.43Å; A362-V400 HydrophobicContact CB-CG1 3.82Å; V363-V400 HydrophobicContact CG2-CB 4.29Å; V363-V400 HydrophobicContact CG2-CG1 4.34Å; V363-V400 HydrophobicContact CG2-CG2 4.1Å; I366-V400 HydrophobicContact CD1-CG2 3.41Å; I366-V400 VanDerWaalsContact CD1-CG2 3.41Å; V396-V400 HydrophobicContact CG1-CG2 4.34Å; V396-V400 VanDerWaalsContact O-CG2 3.31Å; V396-V400 WeakPolarHBondContact O-CG2 3.32Å; V396-V400 PolarHBondContact O-N 3.14Å; Q397-V400 PolarHBondContact O-N 3.33Å; V400-M402 VanDerWaalsContact C-N 3.3Å; V400-M402 PolarHBondContact O-N 3.39Å; V400-V403 PolarHBondContact O-N 3.32Å; V400-L404 HydrophobicContact CG1-CD1 3.89Å; V400-L404 HydrophobicContact CG1-CG 4.43Å; V400-L404 WeakPolarHBondContact O-CG 3.1Å; V400-L404 PolarHBondContact O-N 3.41Å
401R98Very high97.2Very high36 Ų3645.9 Ų45.914%0.13623%0.233CC..Hα-helixtrans-59.1-41.1174.3-68-175.3-175.595-2.9112.3M330 I359 Q397 R399 L404 A405M330-R401 HydrophobicContact CB-CG 3.81Å; M330-R401 HydrophobicContact CG-CG 4.49Å; M330-R401 PolarHBondContact O-NE 2.89Å; M330-R401 VanDerWaalsContact SD-CA 3.57Å; M330-R401 HydrophobicContact SD-CB 3.61Å; M330-R401 HydrophobicContact SD-CG 3.88Å; M330-R401 VanDerWaalsContact SD-O 3.33Å; I359-R401 HydrophobicContact CD1-CG 3.96Å; I359-R401 HydrophobicContact CG2-CG 4.23Å; Q397-R401 WeakPolarHBondContact O-CG 3.33Å; Q397-R401 PolarHBondContact O-N 3Å; R399-R401 VanDerWaalsContact C-N 3.26Å; R399-R401 PolarHBondContact O-N 3.45Å; R401-L404 PolarHBondContact O-N 3.46Å; R401-A405 WeakPolarHBondContact O-CB 3.46Å; R401-A405 PolarHBondContact O-N 3.23Å
402M98.3Very high97.3Very high41 Ų4141.9 Ų41.920%0.20221%0.213CC..Hα-helixtrans-62.4-46.7175.5-179.5-79.7-70.100111.8A398 R399 V400 L404 A405 Y406 Y441A398-M402 PolarHBondContact O-N 2.87Å; R399-M402 WeakPolarHBondContact O-CB 3.27Å; R399-M402 PolarHBondContact O-N 3.27Å; R399-M402 VanDerWaalsContact O-N 3.13Å; V400-M402 VanDerWaalsContact C-N 3.3Å; V400-M402 PolarHBondContact O-N 3.39Å; M402-L404 VanDerWaalsContact C-N 3.29Å; M402-L404 PolarHBondContact O-N 2.89Å; M402-A405 WeakPolarHBondContact O-CB 3.42Å; M402-A405 PolarHBondContact O-N 3.06Å; M402-Y406 HydrophobicContact CG-CD2 4.14Å; M402-Y406 HydrophobicContact CG-CE2 4.26Å; M402-Y406 WeakPolarHBondContact O-CD2 3.4Å; M402-Y406 PolarHBondContact O-N 3.28Å; M402-Y406 VanDerWaalsContact O-N 3.09Å; M402-Y406 HydrophobicContact SD-CD2 3.7Å; M402-Y406 HydrophobicContact SD-CE2 4.11Å; M402-Y441 WeakPolarHBondContact CE-O 3.31Å
403V98.5Very high97.2Very high90 Ų9039.8 Ų39.855%0.54520%0.196SC..Hα-helixtrans-57.9-44.7177.6173.60000111R399 V400 L407R399-V403 PolarHBondContact O-N 3.4Å; V400-V403 PolarHBondContact O-N 3.32Å; V403-L407 PolarHBondContact O-N 2.89Å
404L98.3Very high97.2Very high33 Ų3348.1 Ų48.117%0.17323%0.227CC..Hα-helixtrans-67.4-41.3177.6-67.6170.3000111.7M330 I357 I359 V400 R401 M402 Y406 L407 F408M330-L404 HydrophobicContact SD-CB 4.16Å; I357-L404 HydrophobicContact CD1-CB 4.02Å; I357-L404 HydrophobicContact CD1-CD1 3.82Å; I357-L404 HydrophobicContact CD1-CG 4.4Å; I359-L404 HydrophobicContact CB-CD1 4.41Å; I359-L404 HydrophobicContact CG2-CD1 3.69Å; V400-L404 HydrophobicContact CG1-CD1 3.89Å; V400-L404 HydrophobicContact CG1-CG 4.43Å; V400-L404 WeakPolarHBondContact O-CG 3.1Å; V400-L404 PolarHBondContact O-N 3.41Å; R401-L404 PolarHBondContact O-N 3.46Å; M402-L404 VanDerWaalsContact C-N 3.29Å; M402-L404 PolarHBondContact O-N 2.89Å; L404-Y406 VanDerWaalsContact C-N 3.3Å; L404-Y406 PolarHBondContact O-N 2.92Å; L404-L407 HydrophobicContact CD2-CD2 4.48Å; L404-L407 PolarHBondContact O-N 2.91Å; L404-F408 WeakPolarHBondContact O-CD2 2.98Å; L404-F408 PolarHBondContact O-N 3.19Å
405A98.4Very high97.3Very high1 Ų150.1 Ų50.11%0.00825%0.249CC..Hα-helixtrans-53.1-49.3175.900000111.2L265 P267 M330 R401 M402 F408 A409 V424L265-A405 HydrophobicContact CD2-CB 3.93Å; P267-A405 HydrophobicContact CG-CB 3.84Å; M330-A405 HydrophobicContact CE-CB 3.88Å; R401-A405 WeakPolarHBondContact O-CB 3.46Å; R401-A405 PolarHBondContact O-N 3.23Å; M402-A405 WeakPolarHBondContact O-CB 3.42Å; M402-A405 PolarHBondContact O-N 3.06Å; A405-F408 PolarHBondContact O-N 3.47Å; A405-A409 VanDerWaalsContact O-CB 3.27Å; A405-A409 WeakPolarHBondContact O-CB 3.42Å; A405-A409 PolarHBondContact O-N 3.17Å; A405-V424 HydrophobicContact CB-CG1 4.29Å
406Y98.7Very high97Very high56 Ų5652.9 Ų52.922%0.2226%0.257CS..Hα-helixtrans-69-37.2179.2-86.7-80.5000113.3M402 L404 A409 Q410 V424 A446 D447M402-Y406 HydrophobicContact CG-CD2 4.14Å; M402-Y406 HydrophobicContact CG-CE2 4.26Å; M402-Y406 WeakPolarHBondContact O-CD2 3.4Å; M402-Y406 PolarHBondContact O-N 3.28Å; M402-Y406 VanDerWaalsContact O-N 3.09Å; M402-Y406 HydrophobicContact SD-CD2 3.7Å; M402-Y406 HydrophobicContact SD-CE2 4.11Å; L404-Y406 VanDerWaalsContact C-N 3.3Å; L404-Y406 PolarHBondContact O-N 2.92Å; Y406-A409 PolarHBondContact O-N 3.44Å; Y406-Q410 WeakPolarHBondContact O-CG 3.37Å; Y406-Q410 PolarHBondContact O-N 2.58Å; Y406-V424 HydrophobicContact CD1-CG2 3.81Å; Y406-V424 HydrophobicContact CD2-CG2 4.3Å; Y406-V424 HydrophobicContact CE1-CB 4.29Å; Y406-V424 HydrophobicContact CE1-CG2 3.73Å; Y406-V424 HydrophobicContact CE2-CB 4.43Å; Y406-V424 HydrophobicContact CE2-CG1 4.44Å; Y406-V424 HydrophobicContact CE2-CG2 4.24Å; Y406-V424 HydrophobicContact CG-CG2 4.1Å; Y406-A446 VanDerWaalsContact OH-CA 3.3Å; Y406-A446 WeakPolarHBondContact OH-CA 3.31Å; Y406-D447 VanDerWaalsContact CE1-OD1 3.28Å; Y406-D447 WeakPolarHBondContact CE1-OD1 3.49Å; Y406-D447 PolarHBondContact OH-N 3.19Å; Y406-D447 PolarHBondContact OH-OD1 2.85Å
407L98.4Very high96.7Very high82 Ų8254.9 Ų54.943%0.42928%0.284SS..Hα-helixtrans-60.2-49174.7179.864000111.2V403 L404 A409 Q410 L411V403-L407 PolarHBondContact O-N 2.89Å; L404-L407 HydrophobicContact CD2-CD2 4.48Å; L404-L407 PolarHBondContact O-N 2.91Å; L407-A409 VanDerWaalsContact C-N 3.31Å; L407-A409 PolarHBondContact O-N 3.09Å; L407-Q410 PolarHBondContact O-N 2.99Å; L407-L411 HydrophobicContact CD1-CD1 3.69Å; L407-L411 HydrophobicContact CD1-CG 4.45Å; L407-L411 WeakPolarHBondContact O-CB 3.13Å; L407-L411 PolarHBondContact O-N 3.19Å
408F98.1Very high96.3Very high58 Ų5857.5 Ų57.525%0.25429%0.293SS..Hα-helixtrans-65.9-35.8176.1-84.1-93.5000111.3L265 V355 I357 L404 A405 Q410 L411 S412L265-F408 HydrophobicContact CD1-CB 3.43Å; L265-F408 VanDerWaalsContact CD1-CB 3.43Å; V355-F408 HydrophobicContact CG1-CE1 3.89Å; V355-F408 HydrophobicContact CG1-CZ 4.32Å; I357-F408 HydrophobicContact CD1-CD2 4.48Å; I357-F408 HydrophobicContact CD1-CE2 3.92Å; I357-F408 HydrophobicContact CG2-CE2 4.18Å; I357-F408 HydrophobicContact CG2-CZ 3.83Å; L404-F408 WeakPolarHBondContact O-CD2 2.98Å; L404-F408 PolarHBondContact O-N 3.19Å; A405-F408 PolarHBondContact O-N 3.47Å; F408-Q410 VanDerWaalsContact C-N 3.28Å; F408-Q410 PolarHBondContact O-N 3.15Å; F408-L411 PolarHBondContact O-N 3.13Å; F408-S412 WeakPolarHBondContact CD1-OG 3.32Å; F408-S412 WeakPolarHBondContact O-CA 3.34Å; F408-S412 WeakPolarHBondContact O-CB 3.39Å; F408-S412 PolarHBondContact O-N 2.92Å; F408-S412 PolarHBondContact O-OG 3.32Å
409A98.4Very high95.9Very high2 Ų262.5 Ų62.52%0.01733%0.326CS..Hα-helixtrans-64.4-37.5179.800000111.8L265 A405 Y406 L407 L422 V424L265-A409 HydrophobicContact CB-CB 4.06Å; L265-A409 HydrophobicContact CD1-CB 4.12Å; A405-A409 VanDerWaalsContact O-CB 3.27Å; A405-A409 WeakPolarHBondContact O-CB 3.42Å; A405-A409 PolarHBondContact O-N 3.17Å; Y406-A409 PolarHBondContact O-N 3.44Å; L407-A409 VanDerWaalsContact C-N 3.31Å; L407-A409 PolarHBondContact O-N 3.09Å; A409-L422 HydrophobicContact CB-CB 4.18Å; A409-L422 PolarHBondContact O-N 2.7Å; A409-V424 HydrophobicContact CB-CG2 3.47Å; A409-V424 VanDerWaalsContact CB-CG2 3.47Å
410Q98.3Very high95.4Very high130 Ų13060.2 Ų60.261%0.60733%0.332SS*.Hα-helixtrans-77-34.5177.9-69.9174.84.400113.2Y406 L407 F408Y406-Q410 WeakPolarHBondContact O-CG 3.37Å; Y406-Q410 PolarHBondContact O-N 2.58Å; L407-Q410 PolarHBondContact O-N 2.99Å; F408-Q410 VanDerWaalsContact C-N 3.28Å; F408-Q410 PolarHBondContact O-N 3.15Å
411L97.8Very high95.4Very high77 Ų7760.4 Ų60.440%0.40334%0.336SS..Hα-helixtrans-114.2-10.9-168.7-63.8-178.3000115.7L407 F408 L413 W414 A415L407-L411 HydrophobicContact CD1-CD1 3.69Å; L407-L411 HydrophobicContact CD1-CG 4.45Å; L407-L411 WeakPolarHBondContact O-CB 3.13Å; L407-L411 PolarHBondContact O-N 3.19Å; F408-L411 PolarHBondContact O-N 3.13Å; L411-L413 VanDerWaalsContact C-N 3.34Å; L411-L413 PolarHBondContact O-N 3Å; L411-W414 HydrophobicContact CB-CE3 4.17Å; L411-W414 HydrophobicContact CD2-CD2 4.4Å; L411-W414 HydrophobicContact CD2-CE3 4.23Å; L411-W414 WeakPolarHBondContact O-CB 3.37Å; L411-W414 PolarHBondContact O-N 3.27Å; L411-A415 WeakPolarHBondContact O-CB 3.41Å; L411-A415 PolarHBondContact O-N 3.38Å
412S95.2Very high95.4Very high13 Ų1359.1 Ų59.19%0.09133%0.332CS..Hα-helixtrans-66.6-34.3-176.8-64.60000113.1F408 R416F408-S412 WeakPolarHBondContact CD1-OG 3.32Å; F408-S412 WeakPolarHBondContact O-CA 3.34Å; F408-S412 WeakPolarHBondContact O-CB 3.39Å; F408-S412 PolarHBondContact O-N 2.92Å; F408-S412 PolarHBondContact O-OG 3.32Å; S412-R416 WeakPolarHBondContact O-CG 3.38Å; S412-R416 PolarHBondContact O-N 3.21Å; S412-R416 PolarHBondContact O-NE 3.14Å
413L93.8Very high95.4Very high1 Ų158.2 Ų58.21%0.00533%0.327CS..Hα-helixtrans-72.8-43.4174.2-71177.8000111L411 A415 R416 G417 R418 L422L411-L413 VanDerWaalsContact C-N 3.34Å; L411-L413 PolarHBondContact O-N 3Å; L413-A415 VanDerWaalsContact C-N 3.33Å; L413-A415 PolarHBondContact O-N 3.19Å; L413-R416 CarbonylContact O-C 3.58Å; L413-R416 WeakPolarHBondContact O-CA 3.2Å; L413-R416 PolarHBondContact O-N 2.83Å; L413-G417 PolarHBondContact O-N 3.29Å; L413-R418 CarbonylContact C-O 3.57Å; L413-R418 VanDerWaalsContact C-O 3.23Å; L413-R418 HydrophobicContact CB-CB 4.18Å; L413-R418 HydrophobicContact CD2-CB 4.18Å; L413-R418 PolarHBondContact O-N 2.76Å; L413-L422 HydrophobicContact CD1-CD2 3.65Å; L413-L422 HydrophobicContact CD1-CG 4.14Å; L413-L422 HydrophobicContact CD2-CD2 4.23Å; L413-L422 HydrophobicContact CG-CD2 3.84Å; L413-L422 HydrophobicContact CG-CG 4.12Å
414W96Very high95.4Very high182 Ų18254 Ų5469%0.68930%0.302SS*.Hα-helixtrans-54.6-46.5173.4165.582.1000112.3L411 R416 G417 R418L411-W414 HydrophobicContact CB-CE3 4.17Å; L411-W414 HydrophobicContact CD2-CD2 4.4Å; L411-W414 HydrophobicContact CD2-CE3 4.23Å; L411-W414 WeakPolarHBondContact O-CB 3.37Å; L411-W414 PolarHBondContact O-N 3.27Å; W414-R416 PolarHBondContact O-N 3.28Å; W414-R416 VanDerWaalsContact O-N 3.16Å; W414-G417 PolarHBondContact O-N 3.24Å; W414-R418 PolarHBondContact N-O 3.29Å
415A94.6Very high95.5Very high74 Ų7452.5 Ų52.561%0.61229%0.294SS*.Hα-helixtrans-63.1-21.7177.900000113L411 L413L411-A415 WeakPolarHBondContact O-CB 3.41Å; L411-A415 PolarHBondContact O-N 3.38Å; L413-A415 VanDerWaalsContact C-N 3.33Å; L413-A415 PolarHBondContact O-N 3.19Å
416R90.5Very high95.5Very high88 Ų8852.5 Ų52.533%0.33229%0.294SS..THydrogen-bonded Turntrans-96.48.1174.6-67.7179.4-74.5-176-7.4112.9T326 T353 S412 L413 W414 R418T326-R416 PolarHBondContact OG1-NH2 3.43Å; T326-R416 VanDerWaalsContact OG1-NH2 3.07Å; T353-R416 PolarHBondContact OG1-NH1 3.02Å; S412-R416 WeakPolarHBondContact O-CG 3.38Å; S412-R416 PolarHBondContact O-N 3.21Å; S412-R416 PolarHBondContact O-NE 3.14Å; L413-R416 CarbonylContact O-C 3.58Å; L413-R416 WeakPolarHBondContact O-CA 3.2Å; L413-R416 PolarHBondContact O-N 2.83Å; W414-R416 PolarHBondContact O-N 3.28Å; W414-R416 VanDerWaalsContact O-N 3.16Å; R416-R418 VanDerWaalsContact C-N 3.27Å; R416-R418 PolarHBondContact O-N 3.07Å
417G90.2Very high95.4Very high72 Ų7250.9 Ų50.974%0.74229%0.291SS*.THydrogen-bonded Turntrans69.320.2-178.200000114.4L413 W414L413-G417 PolarHBondContact O-N 3.29Å; W414-G417 PolarHBondContact O-N 3.24Å
418R88.6Confident95.3Very high59 Ų5947.2 Ų47.222%0.22327%0.272CS..  trans-105.5141.5179.5-69.9-179.366.7-151.7-8.6111.2V307 R323 L413 W414 R416V307-R418 PolarHBondContact O-NE 2.94Å; V307-R418 PolarHBondContact O-NH2 2.78Å; R323-R418 PolarHBondContact O-NH1 2.9Å; L413-R418 CarbonylContact C-O 3.57Å; L413-R418 VanDerWaalsContact C-O 3.23Å; L413-R418 HydrophobicContact CB-CB 4.18Å; L413-R418 HydrophobicContact CD2-CB 4.18Å; L413-R418 PolarHBondContact O-N 2.76Å; W414-R418 PolarHBondContact N-O 3.29Å; R416-R418 VanDerWaalsContact C-N 3.27Å; R416-R418 PolarHBondContact O-N 3.07Å
419P87.1Confident95.3Very high112 Ų11244.4 Ų44.473%0.72726%0.26SS*.  trans-73.1162.8174.432.3-35.4000111.7
420G89.4Confident95.2Very high48 Ų4844.3 Ų44.350%0.49526%0.259SS..SBendtrans89.8175.9176.200000114.5
421G96.3Very high95.1Very high14 Ų1438.1 Ų38.114%0.14423%0.231CC..  trans-118.2178.2173.600000111.6Q261 G262Q261-G421 PolarHBondContact OE1-O 3.2Å; G262-G421 PolarHBondContact N-O 3.26Å
422L98.6Very high95Very high9 Ų935.6 Ų35.65%0.04722%0.216CC..  trans-110.1141.3175.5-56.4173.5000110G263 L265 A409 L413G263-L422 WeakPolarHBondContact O-CA 3.32Å; L265-L422 HydrophobicContact CB-CB 4.02Å; L265-L422 HydrophobicContact CB-CD1 4.03Å; L265-L422 HydrophobicContact CD1-CD1 4.45Å; A409-L422 HydrophobicContact CB-CB 4.18Å; A409-L422 PolarHBondContact O-N 2.7Å; L413-L422 HydrophobicContact CD1-CD2 3.65Å; L413-L422 HydrophobicContact CD1-CG 4.14Å; L413-L422 HydrophobicContact CD2-CD2 4.23Å; L413-L422 HydrophobicContact CG-CD2 3.84Å; L413-L422 HydrophobicContact CG-CG 4.12Å
423L98.8Very high95Very high21 Ų2135.1 Ų35.111%0.1121%0.213CC..EExtended strand (participates in β ladder)trans-75.4125.9167.1-68.9171.8000109.4Q261 G263 F264 L265 L425 D447 I448Q261-L423 HydrophobicContact CB-CD1 4.41Å; Q261-L423 HydrophobicContact CB-CG 3.97Å; Q261-L423 HydrophobicContact CG-CD1 4.37Å; Q261-L423 HydrophobicContact CG-CD2 3.76Å; Q261-L423 HydrophobicContact CG-CG 3.74Å; G263-L423 PolarHBondContact O-N 3.06Å; F264-L423 CarbonylContact C-O 3.57Å; F264-L423 WeakPolarHBondContact CA-O 3.36Å; F264-L423 HydrophobicContact CD1-CB 3.77Å; F264-L423 HydrophobicContact CD1-CD1 4.36Å; F264-L423 HydrophobicContact CE1-CB 4.07Å; F264-L423 HydrophobicContact CE1-CD1 3.82Å; L265-L423 PolarHBondContact N-O 3.25Å; L423-L425 PolarHBondContact O-N 3.1Å; L423-D447 WeakPolarHBondContact CA-OD2 3.36Å; L423-D447 HydrophobicContact CD2-CB 4.22Å; L423-I448 HydrophobicContact CD1-CD1 4.29Å
424V98.9Very high95.2Very high3 Ų335.2 Ų35.22%0.01821%0.214CC..EExtended strand (participates in β ladder)trans-74.7124.5173.4-174.40000109L265 A405 Y406 A409 A446 D447 I448L265-V424 HydrophobicContact CD2-CG1 4.41Å; L265-V424 CarbonylContact O-C 3.57Å; L265-V424 WeakPolarHBondContact O-CA 3.46Å; A405-V424 HydrophobicContact CB-CG1 4.29Å; Y406-V424 HydrophobicContact CD1-CG2 3.81Å; Y406-V424 HydrophobicContact CD2-CG2 4.3Å; Y406-V424 HydrophobicContact CE1-CB 4.29Å; Y406-V424 HydrophobicContact CE1-CG2 3.73Å; Y406-V424 HydrophobicContact CE2-CB 4.43Å; Y406-V424 HydrophobicContact CE2-CG1 4.44Å; Y406-V424 HydrophobicContact CE2-CG2 4.24Å; Y406-V424 HydrophobicContact CG-CG2 4.1Å; A409-V424 HydrophobicContact CB-CG2 3.47Å; A409-V424 VanDerWaalsContact CB-CG2 3.47Å; V424-A446 HydrophobicContact CB-CB 4.28Å; V424-A446 HydrophobicContact CG1-CB 3.84Å; V424-A446 WeakPolarHBondContact O-CB 3.44Å; V424-D447 PolarHBondContact N-OD2 3.46Å; V424-D447 PolarHBondContact O-N 3.05Å; V424-I448 PolarHBondContact O-N 3.38Å
425L98.9Very high95.1Very high1 Ų127.2 Ų27.21%0.00519%0.185CC..BIsolated β-bridgetrans-93.8129.3175.5-61.7-176.3000110.8L252 F264 L265 L266 T277 V281 F325 L423 I448L252-L425 HydrophobicContact CD2-CD2 3.95Å; F264-L425 HydrophobicContact CB-CD1 3.86Å; F264-L425 HydrophobicContact CB-CG 4.1Å; F264-L425 HydrophobicContact CD1-CD1 3.99Å; F264-L425 HydrophobicContact CD1-CD2 3.56Å; F264-L425 HydrophobicContact CD1-CG 3.84Å; F264-L425 HydrophobicContact CE1-CD2 3.91Å; F264-L425 HydrophobicContact CG-CD1 3.93Å; F264-L425 HydrophobicContact CG-CD2 4.34Å; F264-L425 HydrophobicContact CG-CG 4.2Å; L265-L425 PolarHBondContact O-N 3.06Å; L266-L425 HydrophobicContact CB-CB 4.46Å; L266-L425 HydrophobicContact CD1-CB 4.03Å; T277-L425 HydrophobicContact CG2-CB 4.03Å; T277-L425 HydrophobicContact CG2-CD1 3.95Å; V281-L425 HydrophobicContact CG2-CD1 3.64Å; F325-L425 HydrophobicContact CE2-CD1 4.23Å; L423-L425 PolarHBondContact O-N 3.1Å; L425-I448 WeakPolarHBondContact CA-O 3.25Å; L425-I448 HydrophobicContact CD2-CD1 4.04Å; L425-I448 HydrophobicContact CD2-CG1 3.67Å
426G98.3Very high95.1Very high1 Ų123.8 Ų23.81%0.0116%0.157CC..PPolyproline II helixtrans-88.1160.9169.900000112A446 I448 N449G426-A446 VanDerWaalsContact N-CB 3.29Å; G426-I448 PolarHBondContact N-O 2.93Å; G426-N449 PolarHBondContact O-OD1 2.97Å
427S97.9Very high95.2Very high22 Ų2222.6 Ų22.615%0.15415%0.153CC..  trans-138.228.6-179.8-57.40000113.5L266 D273 S274 T277L266-S427 WeakPolarHBondContact CD1-OG 3.3Å; D273-S427 WeakPolarHBondContact CB-O 3.41Å; S274-S427 WeakPolarHBondContact CA-OG 3.49Å; T277-S427 PolarHBondContact OG1-OG 3.37Å
428A96.6Very high95.4Very high4 Ų420.3 Ų20.33%0.03312%0.123CC..  trans-73.5136169.200000109.2N449 G452A428-N449 PolarHBondContact N-ND2 3.31Å; A428-N449 PolarHBondContact O-ND2 3.17Å; A428-G452 WeakPolarHBondContact O-CA 3.44Å; A428-G452 PolarHBondContact O-N 3.28Å
429N97.1Very high95.8Very high0 Ų018.3 Ų18.30%012%0.117CC..  trans-90.4172.4173.564.769.2000112D273 D431 E432 S433 K456 L459D273-N429 PolarHBondContact OD2-ND2 3.44Å; N429-D431 VanDerWaalsContact C-N 3.34Å; N429-D431 PolarHBondContact O-N 3.39Å; N429-D431 PolarHBondContact OD1-N 3.06Å; N429-D431 VanDerWaalsContact OD1-N 3.08Å; N429-E432 PolarHBondContact ND2-OE1 2.93Å; N429-E432 PolarHBondContact ND2-OE2 2.97Å; N429-E432 PolarHBondContact OD1-N 3.47Å; N429-S433 VanDerWaalsContact O-CB 3.31Å; N429-S433 WeakPolarHBondContact O-CB 3.26Å; N429-S433 PolarHBondContact O-N 3.37Å; N429-S433 VanDerWaalsContact O-N 3.08Å; N429-S433 PolarHBondContact O-OG 3.13Å; N429-K456 VanDerWaalsContact ND2-CD 3.27Å; N429-K456 WeakPolarHBondContact ND2-CD 3.3Å; N429-K456 PolarHBondContact ND2-NZ 2.88Å; N429-L459 HydrophobicContact CB-CD1 3.72Å
430V97.4Very high96.3Very high0 Ų015.2 Ų15.20%09%0.092CC..Hα-helixtrans-67.8-32.1-17576.90000113L434 I454 Y574 P576V430-L434 WeakPolarHBondContact O-CB 3.42Å; V430-L434 PolarHBondContact O-N 2.97Å; V430-I454 VanDerWaalsContact CG1-C 3.46Å; V430-I454 VanDerWaalsContact CG1-O 3.28Å; V430-I454 WeakPolarHBondContact CG1-O 3.25Å; V430-I454 PolarHBondContact N-O 2.93Å; V430-Y574 HydrophobicContact CG1-CE2 3.8Å; V430-Y574 HydrophobicContact CG2-CE2 4.32Å; V430-P576 VanDerWaalsContact CG2-CD 3.48Å; V430-P576 HydrophobicContact CG2-CG 4.48Å
431D96.1Very high96.7Very high0 Ų018 Ų180%09%0.089CC..Hα-helixtrans-75.3-44.7-175.4-60.3-62000110.9N429 S433 L434 T435 S455 K456 Y507 L510 S511N429-D431 VanDerWaalsContact C-N 3.34Å; N429-D431 PolarHBondContact O-N 3.39Å; N429-D431 PolarHBondContact OD1-N 3.06Å; N429-D431 VanDerWaalsContact OD1-N 3.08Å; D431-S433 VanDerWaalsContact C-N 3.33Å; D431-L434 WeakPolarHBondContact O-CB 3.1Å; D431-L434 PolarHBondContact O-N 3.04Å; D431-T435 PolarHBondContact O-N 3.36Å; D431-T435 VanDerWaalsContact O-N 3.16Å; D431-T435 PolarHBondContact O-OG1 3Å; D431-S455 WeakPolarHBondContact OD2-CA 3.48Å; D431-K456 PolarHBondContact OD2-N 3.22Å; D431-Y507 HydrophobicContact CB-CD1 3.98Å; D431-Y507 HydrophobicContact CB-CE1 4.36Å; D431-L510 HydrophobicContact CB-CB 4.33Å; D431-L510 HydrophobicContact CB-CD1 4.39Å; D431-S511 PolarHBondContact OD1-OG 2.83Å
432E94.4Very high96.7Very high23 Ų2318.5 Ų18.511%0.1079%0.088CC..Hα-helixtrans-64-39.4172.2-71.2168.9-158.500111.5N429 L434 T435 G436 Y437 K456 Y507N429-E432 PolarHBondContact ND2-OE1 2.93Å; N429-E432 PolarHBondContact ND2-OE2 2.97Å; N429-E432 PolarHBondContact OD1-N 3.47Å; E432-L434 VanDerWaalsContact C-N 3.27Å; E432-L434 PolarHBondContact O-N 3.13Å; E432-T435 PolarHBondContact O-N 2.97Å; E432-T435 PolarHBondContact O-OG1 3.49Å; E432-G436 CarbonylContact O-C 3.6Å; E432-G436 WeakPolarHBondContact O-CA 3.3Å; E432-G436 PolarHBondContact O-N 3.07Å; E432-Y437 HydrophobicContact CG-CD1 4.3Å; E432-Y437 PolarHBondContact O-N 2.85Å; E432-K456 IonicContact OE1-NZ 3.09Å; E432-K456 PolarHBondContact OE1-NZ 3.23Å; E432-Y507 HydrophobicContact CG-CE1 4.12Å; E432-Y507 PolarHBondContact OE1-OH 3.37Å
433S96.6Very high96.7Very high4 Ų419.7 Ų19.73%0.02810%0.096CC..Hα-helixtrans-61.9-38.2174.4-62.60000111.3N429 D431 G436N429-S433 VanDerWaalsContact O-CB 3.31Å; N429-S433 WeakPolarHBondContact O-CB 3.26Å; N429-S433 PolarHBondContact O-N 3.37Å; N429-S433 VanDerWaalsContact O-N 3.08Å; N429-S433 PolarHBondContact O-OG 3.13Å; D431-S433 VanDerWaalsContact C-N 3.33Å; S433-G436 PolarHBondContact O-N 3.49Å
434L96.5Very high96.4Very high3 Ų319.1 Ų19.12%0.0169%0.094CC..Hα-helixtrans-66.5-43.5179.8174.764.3000112.1V430 D431 E432 G436 F551 Y555 P576V430-L434 WeakPolarHBondContact O-CB 3.42Å; V430-L434 PolarHBondContact O-N 2.97Å; D431-L434 WeakPolarHBondContact O-CB 3.1Å; D431-L434 PolarHBondContact O-N 3.04Å; E432-L434 VanDerWaalsContact C-N 3.27Å; E432-L434 PolarHBondContact O-N 3.13Å; L434-G436 VanDerWaalsContact C-N 3.3Å; L434-F551 HydrophobicContact CD1-CZ 4.28Å; L434-F551 HydrophobicContact CD2-CE2 4.07Å; L434-F551 HydrophobicContact CD2-CZ 4.13Å; L434-F551 HydrophobicContact CG-CE2 4.08Å; L434-F551 HydrophobicContact CG-CZ 4.15Å; L434-Y555 HydrophobicContact CD1-CD2 4.15Å; L434-Y555 HydrophobicContact CD1-CE2 4.32Å; L434-Y555 WeakPolarHBondContact O-CD2 3.41Å; L434-P576 HydrophobicContact CB-CB 4.34Å; L434-P576 HydrophobicContact CB-CG 4.14Å; L434-P576 HydrophobicContact CD1-CB 4.03Å
435T93.9Very high96.1Very high14 Ų1419.8 Ų19.89%0.08610%0.099CC..Hα-helixtrans-80-16.5177.558.70000112.5D431 E432 Y437 L510 N558D431-T435 PolarHBondContact O-N 3.36Å; D431-T435 VanDerWaalsContact O-N 3.16Å; D431-T435 PolarHBondContact O-OG1 3Å; E432-T435 PolarHBondContact O-N 2.97Å; E432-T435 PolarHBondContact O-OG1 3.49Å; T435-Y437 VanDerWaalsContact C-N 3.28Å; T435-Y437 VanDerWaalsContact OG1-CB 3.31Å; T435-Y437 WeakPolarHBondContact OG1-CB 3.42Å; T435-Y437 PolarHBondContact OG1-N 3.08Å; T435-L510 HydrophobicContact CG2-CD1 3.85Å; T435-L510 HydrophobicContact CG2-CD2 3.48Å; T435-L510 VanDerWaalsContact CG2-CD2 3.48Å; T435-L510 HydrophobicContact CG2-CG 4.32Å; T435-N558 WeakPolarHBondContact O-CB 3.28Å; T435-N558 PolarHBondContact O-ND2 2.99Å
436G94.5Very high96.1Very high2 Ų220.3 Ų20.32%0.02110%0.103CC..THydrogen-bonded Turntrans66.631.7-171.700000112.5E432 S433 L434 F438 K561E432-G436 CarbonylContact O-C 3.6Å; E432-G436 WeakPolarHBondContact O-CA 3.3Å; E432-G436 PolarHBondContact O-N 3.07Å; S433-G436 PolarHBondContact O-N 3.49Å; L434-G436 VanDerWaalsContact C-N 3.3Å; G436-F438 PolarHBondContact O-N 2.96Å; G436-K561 WeakPolarHBondContact O-CD 3.43Å; G436-K561 PolarHBondContact O-NZ 3.24Å
437Y94.3Very high96.1Very high63 Ų6323 Ų2325%0.24712%0.117CC..  trans-8067.3176.9-174.8-105.6000110.7E432 T435 D499 D502 M503E432-Y437 HydrophobicContact CG-CD1 4.3Å; E432-Y437 PolarHBondContact O-N 2.85Å; T435-Y437 VanDerWaalsContact C-N 3.28Å; T435-Y437 VanDerWaalsContact OG1-CB 3.31Å; T435-Y437 WeakPolarHBondContact OG1-CB 3.42Å; T435-Y437 PolarHBondContact OG1-N 3.08Å; Y437-D499 HydrophobicContact CE1-CB 4.08Å; Y437-D502 HydrophobicContact CE2-CB 4.08Å; Y437-D502 VanDerWaalsContact CE2-OD2 3.29Å; Y437-D502 WeakPolarHBondContact CE2-OD2 3.4Å; Y437-D502 WeakPolarHBondContact OH-CB 3.41Å; Y437-D502 PolarHBondContact OH-OD2 3.35Å; Y437-M503 HydrophobicContact CD1-CG 3.72Å; Y437-M503 HydrophobicContact CD1-SD 3.73Å; Y437-M503 HydrophobicContact CD2-CG 3.45Å; Y437-M503 VanDerWaalsContact CD2-CG 3.45Å; Y437-M503 HydrophobicContact CD2-SD 4.36Å; Y437-M503 HydrophobicContact CE1-CG 4.07Å; Y437-M503 HydrophobicContact CE1-SD 4.44Å; Y437-M503 HydrophobicContact CE2-CG 3.82Å; Y437-M503 HydrophobicContact CG-CG 3.4Å; Y437-M503 VanDerWaalsContact CG-CG 3.4Å; Y437-M503 HydrophobicContact CG-SD 3.69Å
438F94.1Very high96.1Very high24 Ų2422.2 Ų22.211%0.10511%0.112CC..SBendtrans-158161.6173.259.4-90.3000110G436 S444 K561 M562 V565G436-F438 PolarHBondContact O-N 2.96Å; F438-S444 WeakPolarHBondContact CD2-OG 3.45Å; F438-K561 HydrophobicContact CD2-CD 4.39Å; F438-K561 HydrophobicContact CE1-CB 4.31Å; F438-K561 HydrophobicContact CE2-CB 3.78Å; F438-K561 HydrophobicContact CE2-CD 4.15Å; F438-K561 HydrophobicContact CE2-CG 4.48Å; F438-K561 HydrophobicContact CZ-CB 3.5Å; F438-K561 HydrophobicContact CZ-CD 4.24Å; F438-K561 HydrophobicContact CZ-CG 4.5Å; F438-K561 WeakPolarHBondContact O-CE 3.43Å; F438-K561 PolarHBondContact O-NZ 3.36Å; F438-M562 HydrophobicContact CE1-SD 4.38Å; F438-M562 HydrophobicContact CZ-SD 4.43Å; F438-V565 HydrophobicContact CZ-CG2 4.31Å
439T96.6Very high96.2Very high17 Ų1722.1 Ų22.110%0.10411%0.11CC..  trans-82.4128.1177.6-59.40000109.8N395 A398 R399 Y441 D442N395-T439 HydrophobicContact CB-CG2 3.91Å; N395-T439 WeakPolarHBondContact OD1-CG2 3.47Å; N395-T439 PolarHBondContact OD1-OG1 3.28Å; A398-T439 HydrophobicContact CB-CG2 4.28Å; R399-T439 HydrophobicContact CG-CG2 4.38Å; T439-Y441 PolarHBondContact O-N 2.82Å; T439-Y441 VanDerWaalsContact O-N 3.12Å; T439-D442 WeakPolarHBondContact CA-OD2 3.41Å; T439-D442 WeakPolarHBondContact CB-OD2 3.38Å; T439-D442 HydrophobicContact CG2-CB 4.29Å; T439-D442 PolarHBondContact N-OD2 3.37Å; T439-D442 PolarHBondContact O-N 2.88Å; T439-D442 VanDerWaalsContact O-N 3.12Å
440K97.8Very high96.3Very high46 Ų4622.1 Ų22.120%0.211%0.11CC..THydrogen-bonded Turntrans-61.4122.7175.7-156.4-179.4-173.7-173.30109.7R399 K561 T564R399-K440 PolarHBondContact NE-O 3.39Å; R399-K440 PolarHBondContact NH2-O 2.95Å; K440-K561 HydrophobicContact CB-CG 4.35Å; K440-K561 HydrophobicContact CD-CG 4.49Å; K440-K561 HydrophobicContact CG-CG 4.41Å; K440-T564 WeakPolarHBondContact CE-OG1 2.95Å
441Y97.8Very high96.4Very high108 Ų10822.1 Ų22.142%0.42411%0.11SC..THydrogen-bonded Turntrans69.328.6-176.7-45.2-59.5000115.9M402 T439 S445 T564M402-Y441 WeakPolarHBondContact CE-O 3.31Å; T439-Y441 PolarHBondContact O-N 2.82Å; T439-Y441 VanDerWaalsContact O-N 3.12Å; Y441-S445 WeakPolarHBondContact CA-OG 3.38Å; Y441-T564 HydrophobicContact CE1-CG2 4.48Å
442D96.9Very high96.5Very high24 Ų2422.2 Ų22.213%0.12811%0.111CC..SBendtrans-87.1-162.6160.269.16.1000111.4A398 T439 S444 S445A398-D442 HydrophobicContact CB-CB 3.59Å; A398-D442 WeakPolarHBondContact O-CB 3.13Å; T439-D442 WeakPolarHBondContact CA-OD2 3.41Å; T439-D442 WeakPolarHBondContact CB-OD2 3.38Å; T439-D442 HydrophobicContact CG2-CB 4.29Å; T439-D442 PolarHBondContact N-OD2 3.37Å; T439-D442 PolarHBondContact O-N 2.88Å; T439-D442 VanDerWaalsContact O-N 3.12Å; D442-S444 PolarHBondContact O-N 2.94Å; D442-S444 WeakPolarHBondContact OD1-CA 3.4Å; D442-S444 WeakPolarHBondContact OD1-CB 3.37Å; D442-S444 PolarHBondContact OD1-N 3.34Å; D442-S444 PolarHBondContact OD1-OG 2.8Å; D442-S445 WeakPolarHBondContact O-CA 3.35Å; D442-S445 VanDerWaalsContact O-CB 3.31Å; D442-S445 WeakPolarHBondContact O-CB 3.35Å; D442-S445 PolarHBondContact O-N 2.97Å
443C96.9Very high96.6Very high33 Ų3321.1 Ų21.122%0.22311%0.106CC..THydrogen-bonded Turntrans-64-4.4177.3-62.30000114.9P267 S445P267-C443 HydrophobicContact CB-CB 4.32Å; P267-C443 HydrophobicContact CG-CB 4.2Å; C443-S445 PolarHBondContact O-N 3.4Å
444S93.1Very high96.7Very high9 Ų920.9 Ų20.96%0.06311%0.105CC..THydrogen-bonded Turntrans-67.9-20.3163.367.80000112.3F438 D442 T566F438-S444 WeakPolarHBondContact CD2-OG 3.45Å; D442-S444 PolarHBondContact O-N 2.94Å; D442-S444 WeakPolarHBondContact OD1-CA 3.4Å; D442-S444 WeakPolarHBondContact OD1-CB 3.37Å; D442-S444 PolarHBondContact OD1-N 3.34Å; D442-S444 PolarHBondContact OD1-OG 2.8Å; S444-T566 PolarHBondContact O-OG1 3.05Å
445S92.6Very high96.8Very high18 Ų1821 Ų2113%0.12611%0.105CC..SBendtrans-97.7101.5173.5-53.40000109.1Y441 D442 C443 T566Y441-S445 WeakPolarHBondContact CA-OG 3.38Å; D442-S445 WeakPolarHBondContact O-CA 3.35Å; D442-S445 VanDerWaalsContact O-CB 3.31Å; D442-S445 WeakPolarHBondContact O-CB 3.35Å; D442-S445 PolarHBondContact O-N 2.97Å; C443-S445 PolarHBondContact O-N 3.4Å; S445-T566 VanDerWaalsContact CA-OG1 3.3Å; S445-T566 WeakPolarHBondContact CA-OG1 3.25Å
446A98.3Very high96.8Very high11 Ų1120.7 Ų20.79%0.09110%0.103CC..SBendtrans-136.5-174-175.600000108.7Y406 V424 G426 T566Y406-A446 VanDerWaalsContact OH-CA 3.3Å; Y406-A446 WeakPolarHBondContact OH-CA 3.31Å; V424-A446 HydrophobicContact CB-CB 4.28Å; V424-A446 HydrophobicContact CG1-CB 3.84Å; V424-A446 WeakPolarHBondContact O-CB 3.44Å; G426-A446 VanDerWaalsContact N-CB 3.29Å; A446-T566 HydrophobicContact CB-CG2 4.18Å; A446-T566 PolarHBondContact N-OG1 3.48Å; A446-T566 VanDerWaalsContact O-CG2 3.3Å; A446-T566 WeakPolarHBondContact O-CG2 3.49Å; A446-T566 PolarHBondContact O-OG1 3.48Å
447D98.7Very high96.9Very high57 Ų5724.6 Ų24.631%0.30512%0.121SC..SBendtrans-77.6-46.3179.6-59.3-32.8000110.7Y406 L423 V424Y406-D447 VanDerWaalsContact CE1-OD1 3.28Å; Y406-D447 WeakPolarHBondContact CE1-OD1 3.49Å; Y406-D447 PolarHBondContact OH-N 3.19Å; Y406-D447 PolarHBondContact OH-OD1 2.85Å; L423-D447 WeakPolarHBondContact CA-OD2 3.36Å; L423-D447 HydrophobicContact CD2-CB 4.22Å; V424-D447 PolarHBondContact N-OD2 3.46Å; V424-D447 PolarHBondContact O-N 3.05Å
448I98.8Very high97Very high7 Ų722.4 Ų22.44%0.03611%0.114CC..BIsolated β-bridgetrans-145153.5176.956.7176.4000111.4W251 L252 Y255 F264 L423 V424 L425 G426 T566W251-I448 HydrophobicContact CH2-CB 3.84Å; W251-I448 HydrophobicContact CH2-CD1 4.39Å; W251-I448 HydrophobicContact CH2-CG2 4.14Å; W251-I448 HydrophobicContact CZ3-CB 4.27Å; W251-I448 HydrophobicContact CZ3-CD1 4.21Å; L252-I448 HydrophobicContact CD2-CD1 3.64Å; L252-I448 HydrophobicContact CD2-CG1 4.45Å; Y255-I448 HydrophobicContact CD1-CD1 3.98Å; Y255-I448 HydrophobicContact CD1-CG2 3.91Å; Y255-I448 HydrophobicContact CE1-CG2 3.63Å; Y255-I448 HydrophobicContact CG-CD1 3.97Å; F264-I448 HydrophobicContact CE1-CD1 4.26Å; L423-I448 HydrophobicContact CD1-CD1 4.29Å; V424-I448 PolarHBondContact O-N 3.38Å; L425-I448 WeakPolarHBondContact CA-O 3.25Å; L425-I448 HydrophobicContact CD2-CD1 4.04Å; L425-I448 HydrophobicContact CD2-CG1 3.67Å; G426-I448 PolarHBondContact N-O 2.93Å; I448-T566 VanDerWaalsContact C-CG2 3.47Å
449N98.8Very high97.2Very high2 Ų221.3 Ų21.31%0.01111%0.109CC..BIsolated β-bridgetrans-129.6107.3178.5179.4-7.3000111.2G426 A428 I451 G452 T566 P567 S568 Y569G426-N449 PolarHBondContact O-OD1 2.97Å; A428-N449 PolarHBondContact N-ND2 3.31Å; A428-N449 PolarHBondContact O-ND2 3.17Å; N449-I451 VanDerWaalsContact C-N 3.27Å; N449-I451 PolarHBondContact O-N 3.28Å; N449-I451 VanDerWaalsContact OD1-CG1 3.27Å; N449-I451 WeakPolarHBondContact OD1-CG1 3.4Å; N449-I451 PolarHBondContact OD1-N 3.33Å; N449-G452 WeakPolarHBondContact ND2-CA 3.34Å; N449-G452 PolarHBondContact OD1-N 2.83Å; N449-T566 HydrophobicContact CB-CG2 3.89Å; N449-P567 PolarHBondContact N-O 3.46Å; N449-S568 CarbonylContact O-C 3.56Å; N449-S568 WeakPolarHBondContact O-CA 3.4Å; N449-S568 WeakPolarHBondContact O-CB 3.4Å; N449-Y569 PolarHBondContact O-N 3.04Å
450P98.8Very high97.3Very high0 Ų023.8 Ų23.80%012%0.119CC..THydrogen-bonded Turntrans-73.5-14.8-177.229.9-34.6000114P248 W251 L252 T277 I280 Y569P248-P450 HydrophobicContact CB-CB 4.26Å; W251-P450 HydrophobicContact CE3-CB 4.46Å; W251-P450 HydrophobicContact CZ3-CB 4.26Å; L252-P450 HydrophobicContact CD1-CB 4.06Å; L252-P450 HydrophobicContact CD1-CG 4.14Å; L252-P450 HydrophobicContact CD2-CB 4.1Å; L252-P450 HydrophobicContact CD2-CG 4.36Å; L252-P450 HydrophobicContact CG-CB 4.08Å; T277-P450 HydrophobicContact CG2-CG 3.69Å; I280-P450 HydrophobicContact CD1-CB 4.3Å; I280-P450 HydrophobicContact CG2-CB 4.4Å; P450-Y569 WeakPolarHBondContact O-CB 3.48Å
451I98.7Very high97.3Very high0 Ų024.1 Ų24.10%013%0.127CC..THydrogen-bonded Turntrans-112.3-3-177.563161.7000114.2D273 I280 N449 G453 I454 L459D273-I451 HydrophobicContact CB-CD1 3.76Å; D273-I451 VanDerWaalsContact O-CD1 3.25Å; D273-I451 WeakPolarHBondContact O-CD1 3.49Å; I280-I451 HydrophobicContact CD1-CG2 3.36Å; N449-I451 VanDerWaalsContact C-N 3.27Å; N449-I451 PolarHBondContact O-N 3.28Å; N449-I451 VanDerWaalsContact OD1-CG1 3.27Å; N449-I451 WeakPolarHBondContact OD1-CG1 3.4Å; N449-I451 PolarHBondContact OD1-N 3.33Å; I451-G453 PolarHBondContact O-N 3.37Å; I451-I454 HydrophobicContact CB-CD1 4.37Å; I451-I454 HydrophobicContact CG2-CD1 4.28Å; I451-I454 WeakPolarHBondContact O-CB 3.38Å; I451-I454 PolarHBondContact O-N 3.47Å; I451-L459 HydrophobicContact CB-CD1 4.45Å; I451-L459 HydrophobicContact CB-CD2 4.01Å; I451-L459 HydrophobicContact CD1-CD1 3.9Å; I451-L459 HydrophobicContact CG2-CD2 3.89Å
452G98Very high97.3Very high1 Ų119 Ų191%0.0111%0.106CC..THydrogen-bonded Turntrans-66.1-9.7-174.600000115.6A428 N449A428-G452 WeakPolarHBondContact O-CA 3.44Å; A428-G452 PolarHBondContact O-N 3.28Å; N449-G452 WeakPolarHBondContact ND2-CA 3.34Å; N449-G452 PolarHBondContact OD1-N 2.83Å
453G97.9Very high97.4Very high0 Ų017.8 Ų17.80%010%0.1CC..THydrogen-bonded Turntrans-100.66.2170.200000114.6I451 Y569 A571 E572I451-G453 PolarHBondContact O-N 3.37Å; G453-Y569 WeakPolarHBondContact CA-O 3.43Å; G453-Y569 PolarHBondContact N-O 3.06Å; G453-A571 WeakPolarHBondContact O-CB 3.49Å; G453-E572 WeakPolarHBondContact O-CB 3.49Å; G453-E572 WeakPolarHBondContact O-CG 3.48Å; G453-E572 PolarHBondContact O-N 3.35Å
454I98.6Very high97.4Very high0 Ų018.2 Ų18.20%011%0.106CC..SBendtrans-113.6141.1-171.4-51.3175.9000110.5I244 P248 V430 I451 D458 L459 A571I244-I454 HydrophobicContact CD1-CG2 3.91Å; I244-I454 HydrophobicContact CG1-CD1 4.21Å; I244-I454 HydrophobicContact CG1-CG2 4.39Å; I244-I454 HydrophobicContact CG2-CD1 3.88Å; P248-I454 HydrophobicContact CG-CD1 4.26Å; V430-I454 VanDerWaalsContact CG1-C 3.46Å; V430-I454 VanDerWaalsContact CG1-O 3.28Å; V430-I454 WeakPolarHBondContact CG1-O 3.25Å; V430-I454 PolarHBondContact N-O 2.93Å; I451-I454 HydrophobicContact CB-CD1 4.37Å; I451-I454 HydrophobicContact CG2-CD1 4.28Å; I451-I454 WeakPolarHBondContact O-CB 3.38Å; I451-I454 PolarHBondContact O-N 3.47Å; I454-D458 HydrophobicContact CG2-CB 3.83Å; I454-L459 HydrophobicContact CB-CD2 4.02Å; I454-L459 HydrophobicContact CB-CG 4.33Å; I454-L459 HydrophobicContact CD1-CD2 4.3Å; I454-L459 HydrophobicContact CG2-CD2 3.73Å; I454-L459 HydrophobicContact CG2-CG 3.93Å; I454-A571 HydrophobicContact CG1-CB 3.91Å
455S97.5Very high97.7Very high4 Ų419.8 Ų19.83%0.02811%0.111CC..  trans-69.8148.9178.4780000113.1D431 M457 D458 L459 Y574D431-S455 WeakPolarHBondContact OD2-CA 3.48Å; S455-M457 PolarHBondContact O-N 3.4Å; S455-D458 PolarHBondContact O-N 2.91Å; S455-D458 VanDerWaalsContact O-N 3.15Å; S455-D458 VanDerWaalsContact OG-CB 3.25Å; S455-D458 WeakPolarHBondContact OG-CB 3.37Å; S455-D458 PolarHBondContact OG-N 3.37Å; S455-D458 PolarHBondContact OG-OD2 3.34Å; S455-L459 WeakPolarHBondContact O-CG 3.38Å; S455-L459 PolarHBondContact O-N 2.93Å; S455-Y574 WeakPolarHBondContact CB-OH 3.41Å
456K95.3Very high98Very high9 Ų918.9 Ų18.94%0.03911%0.105CC..Hα-helixtrans-57.6-36.9176.4-165.282.8170.2-163.30111.8D273 N429 D431 E432 L459 K460 Y507D273-K456 WeakPolarHBondContact OD1-CD 3.48Å; D273-K456 WeakPolarHBondContact OD1-CE 3.39Å; D273-K456 IonicContact OD1-NZ 2.85Å; D273-K456 PolarHBondContact OD1-NZ 2.86Å; D273-K456 IonicContact OD2-NZ 2.82Å; D273-K456 PolarHBondContact OD2-NZ 2.8Å; N429-K456 VanDerWaalsContact ND2-CD 3.27Å; N429-K456 WeakPolarHBondContact ND2-CD 3.3Å; N429-K456 PolarHBondContact ND2-NZ 2.88Å; D431-K456 PolarHBondContact OD2-N 3.22Å; E432-K456 IonicContact OE1-NZ 3.09Å; E432-K456 PolarHBondContact OE1-NZ 3.23Å; K456-L459 PolarHBondContact O-N 2.96Å; K456-K460 PolarHBondContact O-N 3.24Å; K456-K460 VanDerWaalsContact O-N 3.09Å; K456-Y507 HydrophobicContact CB-CD1 3.43Å; K456-Y507 VanDerWaalsContact CB-CD1 3.43Å; K456-Y507 HydrophobicContact CB-CD2 4.41Å; K456-Y507 HydrophobicContact CB-CE1 3.89Å; K456-Y507 HydrophobicContact CB-CG 3.73Å; K456-Y507 HydrophobicContact CD-CD1 4.19Å; K456-Y507 HydrophobicContact CD-CE1 3.78Å; K456-Y507 HydrophobicContact CD-CE2 4.25Å; K456-Y507 HydrophobicContact CG-CD1 3.67Å; K456-Y507 HydrophobicContact CG-CD2 3.89Å; K456-Y507 HydrophobicContact CG-CE1 3.79Å; K456-Y507 HydrophobicContact CG-CE2 4.02Å; K456-Y507 HydrophobicContact CG-CG 3.72Å
457M95.1Very high97.9Very high83 Ų8318.7 Ų18.741%0.40910%0.103SC..Hα-helixtrans-66.8-43.6179.2-65.7-56-61.600111.3S455 L459 K460 S461S455-M457 PolarHBondContact O-N 3.4Å; M457-L459 VanDerWaalsContact C-N 3.34Å; M457-L459 PolarHBondContact O-N 2.89Å; M457-K460 PolarHBondContact O-N 3.03Å; M457-S461 PolarHBondContact O-N 3.28Å; M457-S461 VanDerWaalsContact O-N 3.07Å; M457-S461 PolarHBondContact O-OG 3.4Å
458D97.9Very high97.9Very high18 Ų1822 Ų2210%0.09612%0.117CC..Hα-helixtrans-66.9-35.7176.3-72.2-28.5000112.2R120 I244 I454 S455 S461 F462R120-D458 IonicContact CZ-OD1 2.87Å; R120-D458 IonicContact CZ-OD2 3.71Å; R120-D458 IonicContact NH1-OD1 2.86Å; R120-D458 IonicContact NH1-OD2 3.88Å; R120-D458 PolarHBondContact NH1-OD2 3.39Å; R120-D458 IonicContact NH2-OD1 2.73Å; R120-D458 PolarHBondContact NH2-OD1 2.93Å; R120-D458 IonicContact NH2-OD2 2.67Å; R120-D458 PolarHBondContact NH2-OD2 3.35Å; R120-D458 VanDerWaalsContact NH2-OD2 3.09Å; I244-D458 HydrophobicContact CD1-CB 3.85Å; I454-D458 HydrophobicContact CG2-CB 3.83Å; S455-D458 PolarHBondContact O-N 2.91Å; S455-D458 VanDerWaalsContact O-N 3.15Å; S455-D458 VanDerWaalsContact OG-CB 3.25Å; S455-D458 WeakPolarHBondContact OG-CB 3.37Å; S455-D458 PolarHBondContact OG-N 3.37Å; S455-D458 PolarHBondContact OG-OD2 3.34Å; D458-S461 PolarHBondContact O-N 3.46Å; D458-F462 WeakPolarHBondContact O-CB 3.49Å; D458-F462 PolarHBondContact O-N 3.46Å
459L98.3Very high97.8Very high0 Ų027.1 Ų27.10%014%0.14CC..Hα-helixtrans-62.4-41.7173.9-67.7177.4000112.1V272 N429 I451 I454 S455 K456 M457 F462 L463V272-L459 HydrophobicContact CG1-CB 4.23Å; N429-L459 HydrophobicContact CB-CD1 3.72Å; I451-L459 HydrophobicContact CB-CD1 4.45Å; I451-L459 HydrophobicContact CB-CD2 4.01Å; I451-L459 HydrophobicContact CD1-CD1 3.9Å; I451-L459 HydrophobicContact CG2-CD2 3.89Å; I454-L459 HydrophobicContact CB-CD2 4.02Å; I454-L459 HydrophobicContact CB-CG 4.33Å; I454-L459 HydrophobicContact CD1-CD2 4.3Å; I454-L459 HydrophobicContact CG2-CD2 3.73Å; I454-L459 HydrophobicContact CG2-CG 3.93Å; S455-L459 WeakPolarHBondContact O-CG 3.38Å; S455-L459 PolarHBondContact O-N 2.93Å; K456-L459 PolarHBondContact O-N 2.96Å; M457-L459 VanDerWaalsContact C-N 3.34Å; M457-L459 PolarHBondContact O-N 2.89Å; L459-F462 PolarHBondContact O-N 3.13Å; L459-L463 WeakPolarHBondContact O-CG 3.42Å; L459-L463 PolarHBondContact O-N 3.46Å
460K96.9Very high97.7Very high69 Ų6929.1 Ų29.130%0.315%0.149SC..Hα-helixtrans-62-47.1174.1-73.2-179.4177.6-177.40111.6V272 K456 M457 F462 L463 A464 L479V272-K460 HydrophobicContact CG1-CG 4.1Å; V272-K460 HydrophobicContact CG2-CG 4.48Å; K456-K460 PolarHBondContact O-N 3.24Å; K456-K460 VanDerWaalsContact O-N 3.09Å; M457-K460 PolarHBondContact O-N 3.03Å; K460-F462 VanDerWaalsContact C-N 3.32Å; K460-F462 PolarHBondContact O-N 3.29Å; K460-L463 PolarHBondContact O-N 2.66Å; K460-A464 PolarHBondContact O-N 2.95Å; K460-A464 VanDerWaalsContact O-N 3.12Å; K460-L479 HydrophobicContact CB-CD2 4.17Å; K460-L479 HydrophobicContact CG-CD2 4.32Å
461S97.8Very high97.6Very high53 Ų5335.7 Ų35.737%0.37118%0.18SC..Hα-helixtrans-64.5-37.2177.3-62.40000112.5M457 D458 A464 Y465M457-S461 PolarHBondContact O-N 3.28Å; M457-S461 VanDerWaalsContact O-N 3.07Å; M457-S461 PolarHBondContact O-OG 3.4Å; D458-S461 PolarHBondContact O-N 3.46Å; S461-A464 PolarHBondContact O-N 3.2Å; S461-Y465 PolarHBondContact O-N 2.97Å
462F98.6Very high97.5Very high0 Ų035.8 Ų35.80%018%0.18CC..Hα-helixtrans-63.7-43.1174.8166-115.1000112I244 C279 I280 D458 L459 K460 A464 Y465 C466I244-F462 HydrophobicContact CB-CD2 4Å; I244-F462 HydrophobicContact CB-CE2 4.49Å; I244-F462 HydrophobicContact CB-CG 4.24Å; I244-F462 HydrophobicContact CD1-CB 4.32Å; I244-F462 HydrophobicContact CG2-CB 4.03Å; I244-F462 HydrophobicContact CG2-CD1 3.77Å; I244-F462 HydrophobicContact CG2-CD2 3.57Å; I244-F462 HydrophobicContact CG2-CE1 4.09Å; I244-F462 HydrophobicContact CG2-CE2 3.91Å; I244-F462 HydrophobicContact CG2-CG 3.49Å; I244-F462 VanDerWaalsContact CG2-CG 3.49Å; I244-F462 HydrophobicContact CG2-CZ 4.15Å; C279-F462 HydrophobicContact CB-CE1 3.82Å; C279-F462 HydrophobicContact CB-CZ 3.84Å; I280-F462 HydrophobicContact CD1-CE1 4.49Å; I280-F462 HydrophobicContact CG1-CE1 3.95Å; I280-F462 HydrophobicContact CG1-CZ 3.85Å; D458-F462 WeakPolarHBondContact O-CB 3.49Å; D458-F462 PolarHBondContact O-N 3.46Å; L459-F462 PolarHBondContact O-N 3.13Å; K460-F462 VanDerWaalsContact C-N 3.32Å; K460-F462 PolarHBondContact O-N 3.29Å; F462-A464 VanDerWaalsContact C-N 3.32Å; F462-A464 PolarHBondContact O-N 3.28Å; F462-Y465 HydrophobicContact CD2-CD1 4.4Å; F462-Y465 WeakPolarHBondContact O-CB 3.46Å; F462-Y465 PolarHBondContact O-N 3Å; F462-C466 WeakPolarHBondContact CE2-SG 3.36Å; F462-C466 WeakPolarHBondContact CZ-SG 3.27Å; F462-C466 PolarHBondContact O-N 2.98Å; F462-C466 PolarHBondContact O-SG 2.98Å
463L98.4Very high97.4Very high0 Ų039.5 Ų39.50%020%0.203CC..Hα-helixtrans-63.8-37.3175.4-73-169.9000112.7V272 S276 C279 L459 K460 Y465 C466 A467 L475 I478 L479V272-L463 HydrophobicContact CB-CD1 4.24Å; V272-L463 HydrophobicContact CG1-CD1 3.85Å; V272-L463 HydrophobicContact CG2-CD1 4.42Å; S276-L463 WeakPolarHBondContact OG-CG 3.42Å; C279-L463 HydrophobicContact CB-CD2 4.36Å; L459-L463 WeakPolarHBondContact O-CG 3.42Å; L459-L463 PolarHBondContact O-N 3.46Å; K460-L463 PolarHBondContact O-N 2.66Å; L463-Y465 VanDerWaalsContact C-N 3.33Å; L463-C466 PolarHBondContact O-N 3.44Å; L463-A467 PolarHBondContact O-N 3.1Å; L463-L475 HydrophobicContact CD2-CD1 4.29Å; L463-L475 HydrophobicContact CD2-CD2 3.95Å; L463-L475 WeakPolarHBondContact O-CD1 3.28Å; L463-I478 HydrophobicContact CD1-CG2 4.38Å; L463-L479 HydrophobicContact CB-CD1 4.13Å; L463-L479 HydrophobicContact CB-CD2 4.02Å; L463-L479 HydrophobicContact CB-CG 4.2Å; L463-L479 HydrophobicContact CD1-CD2 4.31Å
464A98.2Very high97.4Very high41 Ų4140.2 Ų40.234%0.33921%0.208SC..Hα-helixtrans-61.9-44.9174.700000110.7K460 S461 F462 C466 A467 E468 L479K460-A464 PolarHBondContact O-N 2.95Å; K460-A464 VanDerWaalsContact O-N 3.12Å; S461-A464 PolarHBondContact O-N 3.2Å; F462-A464 VanDerWaalsContact C-N 3.32Å; F462-A464 PolarHBondContact O-N 3.28Å; A464-C466 PolarHBondContact O-N 2.9Å; A464-A467 WeakPolarHBondContact O-CB 3.2Å; A464-A467 PolarHBondContact O-N 3.28Å; A464-E468 PolarHBondContact O-N 2.99Å; A464-L479 HydrophobicContact CB-CD1 4.07Å
465Y98.4Very high97.3Very high42 Ų4240.2 Ų40.217%0.16521%0.208CC..Hα-helixtrans-58.2-46.3172.1167.8-88.4000112.1Q241 E242 S461 F462 L463 A467 E468 Q469Q241-Y465 HydrophobicContact CB-CD1 4.1Å; Q241-Y465 HydrophobicContact CB-CD2 3.87Å; Q241-Y465 HydrophobicContact CB-CG 3.63Å; Q241-Y465 HydrophobicContact CG-CG 4.41Å; E242-Y465 HydrophobicContact CG-CE2 3.84Å; E242-Y465 WeakPolarHBondContact CG-OH 3.21Å; S461-Y465 PolarHBondContact O-N 2.97Å; F462-Y465 HydrophobicContact CD2-CD1 4.4Å; F462-Y465 WeakPolarHBondContact O-CB 3.46Å; F462-Y465 PolarHBondContact O-N 3Å; L463-Y465 VanDerWaalsContact C-N 3.33Å; Y465-A467 VanDerWaalsContact C-N 3.32Å; Y465-A467 PolarHBondContact O-N 3.38Å; Y465-E468 PolarHBondContact O-N 2.73Å; Y465-Q469 HydrophobicContact CD1-CB 4.49Å; Y465-Q469 HydrophobicContact CD1-CG 4.12Å; Y465-Q469 HydrophobicContact CD2-CG 3.68Å; Y465-Q469 HydrophobicContact CE1-CB 4.14Å; Y465-Q469 HydrophobicContact CE1-CG 3.82Å; Y465-Q469 HydrophobicContact CE2-CG 3.39Å; Y465-Q469 HydrophobicContact CG-CG 4.04Å; Y465-Q469 VanDerWaalsContact CZ-CG 3.46Å; Y465-Q469 WeakPolarHBondContact O-CB 3.29Å; Y465-Q469 WeakPolarHBondContact O-CG 3.47Å; Y465-Q469 PolarHBondContact O-N 3.15Å
466C98.4Very high97.2Very high0 Ų047.4 Ų47.40%024%0.235CC..Hα-helixtrans-64.1-34.6178-73.40000113.4C279 F462 L463 A464 E468 F470 L475C279-C466 HydrophobicContact CB-CB 4.33Å; F462-C466 WeakPolarHBondContact CE2-SG 3.36Å; F462-C466 WeakPolarHBondContact CZ-SG 3.27Å; F462-C466 PolarHBondContact O-N 2.98Å; F462-C466 PolarHBondContact O-SG 2.98Å; L463-C466 PolarHBondContact O-N 3.44Å; A464-C466 PolarHBondContact O-N 2.9Å; C466-E468 PolarHBondContact O-N 3.1Å; C466-F470 HydrophobicContact CB-CD2 3.9Å; C466-F470 HydrophobicContact CB-CE2 4.47Å; C466-F470 WeakPolarHBondContact O-CA 3.26Å; C466-F470 WeakPolarHBondContact O-CB 3.4Å; C466-F470 PolarHBondContact O-N 3.3Å; C466-L475 HydrophobicContact CB-CD1 3.63Å
467A97.8Very high97.1Very high6 Ų648.9 Ų48.95%0.0525%0.252CS..Hα-helixtrans-61.1-35.2176.800000111.2L463 A464 Y465 Q471 L472 L475L463-A467 PolarHBondContact O-N 3.1Å; A464-A467 WeakPolarHBondContact O-CB 3.2Å; A464-A467 PolarHBondContact O-N 3.28Å; Y465-A467 VanDerWaalsContact C-N 3.32Å; Y465-A467 PolarHBondContact O-N 3.38Å; A467-Q471 WeakPolarHBondContact O-CA 3.44Å; A467-Q471 PolarHBondContact O-N 2.9Å; A467-L472 PolarHBondContact O-N 3.32Å; A467-L475 HydrophobicContact CB-CB 3.98Å; A467-L475 HydrophobicContact CB-CD1 4.24Å
468E96.9Very high97.1Very high128 Ų12845 Ų4560%0.59823%0.233SC*.Hα-helixtrans-85.2-50.7178.2-65.1178.2-179.300112.2A464 Y465 C466 Q471A464-E468 PolarHBondContact O-N 2.99Å; Y465-E468 PolarHBondContact O-N 2.73Å; C466-E468 PolarHBondContact O-N 3.1Å; E468-Q471 PolarHBondContact O-NE2 2.78Å
469Q97.5Very high97Very high114 Ų11446.9 Ų46.953%0.53324%0.243SC..Hα-helixtrans-73-38.9-173.2-65.7-60.8-39.100113.3Y465Y465-Q469 HydrophobicContact CD1-CB 4.49Å; Y465-Q469 HydrophobicContact CD1-CG 4.12Å; Y465-Q469 HydrophobicContact CD2-CG 3.68Å; Y465-Q469 HydrophobicContact CE1-CB 4.14Å; Y465-Q469 HydrophobicContact CE1-CG 3.82Å; Y465-Q469 HydrophobicContact CE2-CG 3.39Å; Y465-Q469 HydrophobicContact CG-CG 4.04Å; Y465-Q469 VanDerWaalsContact CZ-CG 3.46Å; Y465-Q469 WeakPolarHBondContact O-CB 3.29Å; Y465-Q469 WeakPolarHBondContact O-CG 3.47Å; Y465-Q469 PolarHBondContact O-N 3.15Å
470F96.9Very high96.7Very high44 Ų4451 Ų5119%0.19328%0.277CS..SBendtrans-101.42.9179.7-56.5-48.7000112.9H282 V286 C466 L472H282-F470 AromaticContact CD2-CG 3.98Å; V286-F470 HydrophobicContact CG2-CD1 4.35Å; V286-F470 HydrophobicContact CG2-CE1 4.17Å; C466-F470 HydrophobicContact CB-CD2 3.9Å; C466-F470 HydrophobicContact CB-CE2 4.47Å; C466-F470 WeakPolarHBondContact O-CA 3.26Å; C466-F470 WeakPolarHBondContact O-CB 3.4Å; C466-F470 PolarHBondContact O-N 3.3Å; F470-L472 HydrophobicContact CB-CD1 3.94Å; F470-L472 HydrophobicContact CB-CG 3.8Å; F470-L472 PolarHBondContact O-N 3.43Å
471Q96.8Very high96.3Very high138 Ų13848.8 Ų48.865%0.64527%0.272SS*.  trans55.238.9179.6-59.1-67.6-39.600113A467 E468 T473A467-Q471 WeakPolarHBondContact O-CA 3.44Å; A467-Q471 PolarHBondContact O-N 2.9Å; E468-Q471 PolarHBondContact O-NE2 2.78Å; Q471-T473 PolarHBondContact O-N 3.05Å
472L96.9Very high95.4Very high2 Ų249.7 Ų49.71%0.0128%0.276CS..  trans-90.990.1179.6-58.3176.1000109.8L346 E349 I350 A467 F470 A474 L475L346-L472 HydrophobicContact CD1-CD1 4.42Å; E349-L472 HydrophobicContact CB-CD2 3.79Å; E349-L472 WeakPolarHBondContact OE2-CA 3.29Å; I350-L472 HydrophobicContact CG2-CD1 3.9Å; I350-L472 HydrophobicContact CG2-CD2 3.9Å; A467-L472 PolarHBondContact O-N 3.32Å; F470-L472 HydrophobicContact CB-CD1 3.94Å; F470-L472 HydrophobicContact CB-CG 3.8Å; F470-L472 PolarHBondContact O-N 3.43Å; L472-A474 VanDerWaalsContact C-N 3.31Å; L472-A474 PolarHBondContact O-N 3.28Å; L472-L475 HydrophobicContact CB-CD1 3.73Å; L472-L475 HydrophobicContact CB-CG 3.91Å; L472-L475 HydrophobicContact CD1-CD1 4.06Å; L472-L475 WeakPolarHBondContact O-CB 3.38Å; L472-L475 PolarHBondContact O-N 3.08Å
473T96Very high94.3Very high79 Ų7951.6 Ų51.649%0.48529%0.289SS..THydrogen-bonded Turntrans-70.5-26.8-172.468.20000113.3E349 Q471 L475 R476E349-T473 WeakPolarHBondContact OE1-CA 3.34Å; E349-T473 WeakPolarHBondContact OE1-CB 3.22Å; E349-T473 PolarHBondContact OE1-N 3.34Å; E349-T473 PolarHBondContact OE1-OG1 3.09Å; E349-T473 PolarHBondContact OE2-N 3.18Å; Q471-T473 PolarHBondContact O-N 3.05Å; T473-L475 PolarHBondContact O-N 3.3Å; T473-L475 VanDerWaalsContact O-N 3.14Å; T473-R476 WeakPolarHBondContact O-CB 3.25Å; T473-R476 PolarHBondContact O-N 2.8Å; T473-R476 VanDerWaalsContact O-N 3.1Å
474A96.5Very high93.2Very high14 Ų1453.3 Ų53.312%0.11630%0.299CS..Hα-helixtrans-58-28.3176.200000112.4D345 L346 E349 L472 R476 G477 I478D345-A474 HydrophobicContact CB-CB 3.95Å; L346-A474 HydrophobicContact CB-CB 4.12Å; E349-A474 PolarHBondContact OE1-N 3.44Å; E349-A474 VanDerWaalsContact OE1-N 3.08Å; E349-A474 VanDerWaalsContact OE2-CB 3.28Å; E349-A474 WeakPolarHBondContact OE2-CB 3.27Å; E349-A474 PolarHBondContact OE2-N 2.91Å; L472-A474 VanDerWaalsContact C-N 3.31Å; L472-A474 PolarHBondContact O-N 3.28Å; A474-R476 VanDerWaalsContact C-N 3.25Å; A474-R476 PolarHBondContact O-N 2.63Å; A474-G477 PolarHBondContact O-N 2.96Å; A474-I478 PolarHBondContact O-N 3.4Å
475L97.4Very high92Very high0 Ų053.7 Ų53.70%030%0.302CS..Hα-helixtrans-63.7-28179-64.1-178.7000113.4L346 L463 C466 A467 L472 T473 I478 L479L346-L475 HydrophobicContact CD1-CD2 3.69Å; L346-L475 HydrophobicContact CD1-CG 4.14Å; L346-L475 HydrophobicContact CD2-CD2 4.01Å; L346-L475 HydrophobicContact CG-CD2 4.49Å; L463-L475 HydrophobicContact CD2-CD1 4.29Å; L463-L475 HydrophobicContact CD2-CD2 3.95Å; L463-L475 WeakPolarHBondContact O-CD1 3.28Å; C466-L475 HydrophobicContact CB-CD1 3.63Å; A467-L475 HydrophobicContact CB-CB 3.98Å; A467-L475 HydrophobicContact CB-CD1 4.24Å; L472-L475 HydrophobicContact CB-CD1 3.73Å; L472-L475 HydrophobicContact CB-CG 3.91Å; L472-L475 HydrophobicContact CD1-CD1 4.06Å; L472-L475 WeakPolarHBondContact O-CB 3.38Å; L472-L475 PolarHBondContact O-N 3.08Å; T473-L475 PolarHBondContact O-N 3.3Å; T473-L475 VanDerWaalsContact O-N 3.14Å; L475-I478 HydrophobicContact CD2-CD1 3.97Å; L475-I478 PolarHBondContact O-N 2.93Å; L475-L479 WeakPolarHBondContact O-CB 3.4Å; L475-L479 WeakPolarHBondContact O-CG 3.42Å; L475-L479 PolarHBondContact O-N 3.09Å
476R95.1Very high91.1Very high156 Ų15652.9 Ų52.959%0.58930%0.3SS*.Hα-helixtrans-63.9-43.3177-65.3-179179.7159.11.6111.2T473 A474 I478 L479 A480T473-R476 WeakPolarHBondContact O-CB 3.25Å; T473-R476 PolarHBondContact O-N 2.8Å; T473-R476 VanDerWaalsContact O-N 3.1Å; A474-R476 VanDerWaalsContact C-N 3.25Å; A474-R476 PolarHBondContact O-N 2.63Å; R476-I478 VanDerWaalsContact C-N 3.34Å; R476-L479 PolarHBondContact O-N 3.08Å; R476-A480 WeakPolarHBondContact O-CB 3.47Å; R476-A480 PolarHBondContact O-N 3.35Å; R476-A480 VanDerWaalsContact O-N 3.09Å
477G93.6Very high90.1Very high39 Ų3954.2 Ų54.240%0.40231%0.307SS..Hα-helixtrans-66-3617500000112.5A474 A481A474-G477 PolarHBondContact O-N 2.96Å; G477-A481 PolarHBondContact O-N 2.96Å
478I95.3Very high89.1Confident2 Ų255.7 Ų55.71%0.0131%0.313CS..Hα-helixtrans-67.3-42.2176.5-66.6159.2000111.5V272 S275 R342 L346 L463 A474 L475 R476 A481V272-I478 HydrophobicContact CG2-CG2 4.39Å; S275-I478 WeakPolarHBondContact OG-CD1 3.14Å; R342-I478 HydrophobicContact CB-CD1 4.5Å; R342-I478 HydrophobicContact CB-CG1 3.93Å; R342-I478 HydrophobicContact CG-CG1 4.22Å; L346-I478 HydrophobicContact CB-CD1 4.21Å; L346-I478 HydrophobicContact CD2-CD1 3.92Å; L463-I478 HydrophobicContact CD1-CG2 4.38Å; A474-I478 PolarHBondContact O-N 3.4Å; L475-I478 HydrophobicContact CD2-CD1 3.97Å; L475-I478 PolarHBondContact O-N 2.93Å; R476-I478 VanDerWaalsContact C-N 3.34Å; I478-A481 PolarHBondContact O-N 3.04Å
479L94.6Very high88.1Confident57 Ų5750.8 Ų50.830%0.29829%0.292SS..Hα-helixtrans-69.6-33.2178.8-77.1169.3000113.2K460 L463 A464 L475 R476 A481K460-L479 HydrophobicContact CB-CD2 4.17Å; K460-L479 HydrophobicContact CG-CD2 4.32Å; L463-L479 HydrophobicContact CB-CD1 4.13Å; L463-L479 HydrophobicContact CB-CD2 4.02Å; L463-L479 HydrophobicContact CB-CG 4.2Å; L463-L479 HydrophobicContact CD1-CD2 4.31Å; A464-L479 HydrophobicContact CB-CD1 4.07Å; L475-L479 WeakPolarHBondContact O-CB 3.4Å; L475-L479 WeakPolarHBondContact O-CG 3.42Å; L475-L479 PolarHBondContact O-N 3.09Å; R476-L479 PolarHBondContact O-N 3.08Å; L479-A481 VanDerWaalsContact C-N 3.34Å
480A92.6Very high86.7Confident86 Ų8648.6 Ų48.671%0.71128%0.284SS*.Hα-helixtrans-77.1-20.3177.600000113.2R476R476-A480 WeakPolarHBondContact O-CB 3.47Å; R476-A480 PolarHBondContact O-N 3.35Å; R476-A480 VanDerWaalsContact O-N 3.09Å
481A87.8Confident85Confident23 Ų2352.4 Ų52.419%0.1930%0.3CS..SBendtrans-71.2141.1-178.500000111.8G477 I478 L479G477-A481 PolarHBondContact O-N 2.96Å; I478-A481 PolarHBondContact O-N 3.04Å; L479-A481 VanDerWaalsContact C-N 3.34Å
482P78.9Confident83Confident72 Ų7253.7 Ų53.747%0.46831%0.311SS..PPolyproline II helixtrans-65.8137.9174.927.7-33.8000110.6T484 L495P482-T484 PolarHBondContact O-N 2.87Å; P482-L495 HydrophobicContact CG-CD1 3.58Å
483P76.8Confident81Confident41 Ų4156.6 Ų56.627%0.26634%0.342SS..PPolyproline II helixtrans-72.2116.9177.129.3-32.6000110T498 D499P483-T498 VanDerWaalsContact O-CA 3.27Å; P483-T498 WeakPolarHBondContact O-CA 3.29Å; P483-T498 WeakPolarHBondContact O-CB 3.37Å; P483-D499 PolarHBondContact O-N 3.47Å
484T75.6Confident79Confident35 Ų3560 Ų6022%0.21535%0.353CS..  trans-154.4144.3-175.8-173.40000111P482 E486 L495 Q497P482-T484 PolarHBondContact O-N 2.87Å; T484-E486 HydrophobicContact CG2-CG 4.32Å; T484-L495 HydrophobicContact CG2-CD1 3.85Å; T484-L495 HydrophobicContact CG2-CD2 3.51Å; T484-L495 HydrophobicContact CG2-CG 4.26Å; T484-Q497 PolarHBondContact OG1-O 2.67Å
485A72Confident77.2Confident49 Ų4963 Ų6341%0.40537%0.366SS..  trans-94.6106.4169.200000109.6L487A485-L487 HydrophobicContact CB-CD1 4.2Å; A485-L487 HydrophobicContact CB-CG 4.18Å; A485-L487 PolarHBondContact O-N 2.82Å
486E78.8Confident75.3Confident25 Ų2565.5 Ų65.512%0.11738%0.384CS..  trans-74.461.2177.4-61.5179.7165.500111.6S335 S336 T339 T484 L495S335-E486 WeakPolarHBondContact CA-OE2 3.37Å; S336-E486 WeakPolarHBondContact CB-OE1 3.29Å; S336-E486 PolarHBondContact N-OE2 2.96Å; S336-E486 PolarHBondContact OG-OE1 2.75Å; S336-E486 PolarHBondContact OG-OE2 3.08Å; T339-E486 VanDerWaalsContact CG2-CD 3.41Å; T339-E486 HydrophobicContact CG2-CG 4.47Å; T339-E486 WeakPolarHBondContact CG2-OE1 2.98Å; T339-E486 VanDerWaalsContact CG2-OE2 3.32Å; T339-E486 WeakPolarHBondContact CG2-OE2 3.37Å; T339-E486 PolarHBondContact OG1-OE2 3.39Å; T484-E486 HydrophobicContact CG2-CG 4.32Å; E486-L495 HydrophobicContact CG-CD2 4.25Å
487L77.4Confident74.1Confident28 Ų2861.8 Ų61.815%0.14737%0.373CS..  trans-109.5-9.5-178.3-60.6179.8000113.3N334 F380 Q394 Q397 A485N334-L487 PolarHBondContact ND2-O 3.28Å; F380-L487 VanDerWaalsContact CE1-O 3.29Å; F380-L487 WeakPolarHBondContact CE1-O 3.45Å; Q394-L487 HydrophobicContact CB-CB 4.09Å; Q394-L487 HydrophobicContact CB-CD1 4.21Å; Q394-L487 HydrophobicContact CG-CB 3.76Å; Q397-L487 HydrophobicContact CB-CD2 4.45Å; Q397-L487 PolarHBondContact NE2-O 2.96Å; A485-L487 HydrophobicContact CB-CD1 4.2Å; A485-L487 HydrophobicContact CB-CG 4.18Å; A485-L487 PolarHBondContact O-N 2.82Å
488E78.4Confident73.4Confident38 Ų3862.6 Ų62.618%0.17837%0.37CS..SBendtrans-115.1152.2175.9-64.8-173.2-176.700111N334 N390 Q394 L490N334-E488 WeakPolarHBondContact CB-O 3.18Å; N390-E488 PolarHBondContact ND2-OE1 3.15Å; Q394-E488 HydrophobicContact CG-CG 4.18Å; Q394-E488 PolarHBondContact NE2-OE1 3.24Å; E488-L490 PolarHBondContact O-N 2.95Å
489P74.8Confident72.8Confident24 Ų2463.4 Ų63.416%0.15638%0.375CS..PPolyproline II helixtrans-54.8136171.2-23.732.6000111.6N334 F380 A382 K491 S496N334-P489 VanDerWaalsContact OD1-CA 3.29Å; N334-P489 WeakPolarHBondContact OD1-CA 3.18Å; F380-P489 HydrophobicContact CB-CG 4.02Å; F380-P489 HydrophobicContact CD2-CG 3.69Å; F380-P489 HydrophobicContact CE2-CG 4.25Å; F380-P489 VanDerWaalsContact CG-CD 3.46Å; F380-P489 HydrophobicContact CG-CG 3.84Å; A382-P489 HydrophobicContact CB-CB 4.37Å; P489-K491 PolarHBondContact O-N 3.17Å; P489-S496 PolarHBondContact O-OG 3.33Å
490L68.9Low72.4Confident69 Ų6963.4 Ų63.436%0.36137%0.373SS..PPolyproline II helixtrans-63.4129.9173.5-60.8171.2000109.5E488 L495E488-L490 PolarHBondContact O-N 2.95Å; L490-L495 HydrophobicContact CD2-CD2 4.02Å
491K60.6Low71.9Confident124 Ų12462.9 Ų62.954%0.53936%0.364SS..BIsolated β-bridgetrans-83.4118.7169.9-101-175.6173.6-1790108.8P489 G493 Q494P489-K491 PolarHBondContact O-N 3.17Å; K491-G493 PolarHBondContact O-N 3.28Å; K491-G493 VanDerWaalsContact O-N 3.08Å; K491-Q494 PolarHBondContact N-O 3.21Å; K491-Q494 PolarHBondContact O-N 2.99Å
492D54.7Low71.7Confident164 Ų16465.9 Ų65.988%0.87738%0.377SS*.THydrogen-bonded Turntrans52.631.9178.2-56.4-46.3000114.2Q494D492-Q494 VanDerWaalsContact C-N 3.25Å; D492-Q494 PolarHBondContact O-N 2.82Å
493G54.7Low72.1Confident64 Ų6463.2 Ų63.266%0.6636%0.359SS*.THydrogen-bonded Turntrans75.56.6-177.300000115K491K491-G493 PolarHBondContact O-N 3.28Å; K491-G493 VanDerWaalsContact O-N 3.08Å
494Q54.6Low72.7Confident150 Ų15063.2 Ų63.270%0.70137%0.366SS*.BIsolated β-bridgetrans-107.4150.5176.2-63.4-168.1-1.300112K491 D492 S496K491-Q494 PolarHBondContact N-O 3.21Å; K491-Q494 PolarHBondContact O-N 2.99Å; D492-Q494 VanDerWaalsContact C-N 3.25Å; D492-Q494 PolarHBondContact O-N 2.82Å; Q494-S496 PolarHBondContact O-N 3.09Å
495L59.4Low73.4Confident76 Ų7661.9 Ų61.940%0.39836%0.357SS..  trans-62.8127.4176.5-72.3164.6000110.4P482 T484 E486 L490P482-L495 HydrophobicContact CG-CD1 3.58Å; T484-L495 HydrophobicContact CG2-CD1 3.85Å; T484-L495 HydrophobicContact CG2-CD2 3.51Å; T484-L495 HydrophobicContact CG2-CG 4.26Å; E486-L495 HydrophobicContact CG-CD2 4.25Å; L490-L495 HydrophobicContact CD2-CD2 4.02Å
496S57.3Low74.4Confident53 Ų5363.9 Ų63.937%0.37136%0.359SS..  trans-72.7-31.9-173.7-57.50000113.4P489 Q494P489-S496 PolarHBondContact O-OG 3.33Å; Q494-S496 PolarHBondContact O-N 3.09Å
497Q69.3Low75Confident78 Ų7862.7 Ų62.736%0.36435%0.354SS..  trans-164.8150.1-174.8-158.1167.9-18.700113.6T484 D502T484-Q497 PolarHBondContact OG1-O 2.67Å; Q497-D502 HydrophobicContact CG-CB 4.45Å; Q497-D502 VanDerWaalsContact NE2-CB 3.3Å; Q497-D502 PolarHBondContact NE2-OD1 2.96Å
498T79.8Confident75.7Confident56 Ų5664.2 Ų64.234%0.34437%0.367SS..  trans-96155.1170.561.40000111.9P483 E500 S501 D502P483-T498 VanDerWaalsContact O-CA 3.27Å; P483-T498 WeakPolarHBondContact O-CA 3.29Å; P483-T498 WeakPolarHBondContact O-CB 3.37Å; T498-E500 VanDerWaalsContact C-N 3.31Å; T498-E500 PolarHBondContact O-N 2.84Å; T498-S501 WeakPolarHBondContact O-CB 3.43Å; T498-S501 PolarHBondContact O-N 3.23Å; T498-S501 VanDerWaalsContact O-N 3.11Å; T498-S501 WeakPolarHBondContact OG1-CB 3.28Å; T498-S501 PolarHBondContact OG1-N 3.02Å; T498-D502 PolarHBondContact O-N 3.2Å; T498-D502 VanDerWaalsContact O-N 3.08Å
499D82.1Confident76.4Confident19 Ų1963.1 Ų63.110%0.10236%0.361CS..Hα-helixtrans-58.3-40.7-178.9-56.2-22.8000112.8Y437 P483 S501 D502 M503Y437-D499 HydrophobicContact CE1-CB 4.08Å; P483-D499 PolarHBondContact O-N 3.47Å; D499-S501 VanDerWaalsContact C-N 3.32Å; D499-S501 PolarHBondContact O-N 2.93Å; D499-D502 PolarHBondContact O-N 3.41Å; D499-M503 WeakPolarHBondContact O-CB 3.13Å; D499-M503 WeakPolarHBondContact O-CG 3.03Å; D499-M503 PolarHBondContact O-N 3.45Å
500E85.1Confident77.4Confident58 Ų5862 Ų6227%0.27135%0.354SS..Hα-helixtrans-67-34.3179.3-66.1-174134.600112.1T498 G504 M505 M506 Y507T498-E500 VanDerWaalsContact C-N 3.31Å; T498-E500 PolarHBondContact O-N 2.84Å; E500-G504 PolarHBondContact O-N 3.39Å; E500-M505 WeakPolarHBondContact CA-O 3.23Å; E500-M505 PolarHBondContact O-N 3.46Å; E500-M505 VanDerWaalsContact O-N 3.17Å; E500-M506 VanDerWaalsContact OE1-CA 3.32Å; E500-M506 WeakPolarHBondContact OE1-CA 3.45Å; E500-Y507 HydrophobicContact CG-CD2 3.58Å; E500-Y507 HydrophobicContact CG-CE2 3.74Å; E500-Y507 VanDerWaalsContact OE1-CD2 3.28Å; E500-Y507 WeakPolarHBondContact OE1-CD2 3.34Å; E500-Y507 PolarHBondContact OE1-N 3.04Å
501S83.4Confident78.5Confident74 Ų7458.9 Ų58.952%0.51734%0.338SS..Hα-helixtrans-66.5-44.2174.5-176.90000110.7T498 D499 G504T498-S501 WeakPolarHBondContact O-CB 3.43Å; T498-S501 PolarHBondContact O-N 3.23Å; T498-S501 VanDerWaalsContact O-N 3.11Å; T498-S501 WeakPolarHBondContact OG1-CB 3.28Å; T498-S501 PolarHBondContact OG1-N 3.02Å; D499-S501 VanDerWaalsContact C-N 3.32Å; D499-S501 PolarHBondContact O-N 2.93Å; S501-G504 PolarHBondContact O-N 3.49Å
502D82.7Confident80.2Confident86 Ų8654.7 Ų54.746%0.4632%0.323SS..Hα-helixtrans-69.2-38.9178.8-158.141.2000113.3Y437 Q497 T498 D499 G504Y437-D502 HydrophobicContact CE2-CB 4.08Å; Y437-D502 VanDerWaalsContact CE2-OD2 3.29Å; Y437-D502 WeakPolarHBondContact CE2-OD2 3.4Å; Y437-D502 WeakPolarHBondContact OH-CB 3.41Å; Y437-D502 PolarHBondContact OH-OD2 3.35Å; Q497-D502 HydrophobicContact CG-CB 4.45Å; Q497-D502 VanDerWaalsContact NE2-CB 3.3Å; Q497-D502 PolarHBondContact NE2-OD1 2.96Å; T498-D502 PolarHBondContact O-N 3.2Å; T498-D502 VanDerWaalsContact O-N 3.08Å; D499-D502 PolarHBondContact O-N 3.41Å; D502-G504 PolarHBondContact O-N 3.36Å
503M87.8Confident82.2Confident17 Ų1746.9 Ų46.98%0.08428%0.281CS..Hα-helixtrans-68.3-23.9171.8-72.5-168.4-6700112.9Y437 D499 M505 Y507 L510 H550Y437-M503 HydrophobicContact CD1-CG 3.72Å; Y437-M503 HydrophobicContact CD1-SD 3.73Å; Y437-M503 HydrophobicContact CD2-CG 3.45Å; Y437-M503 VanDerWaalsContact CD2-CG 3.45Å; Y437-M503 HydrophobicContact CD2-SD 4.36Å; Y437-M503 HydrophobicContact CE1-CG 4.07Å; Y437-M503 HydrophobicContact CE1-SD 4.44Å; Y437-M503 HydrophobicContact CE2-CG 3.82Å; Y437-M503 HydrophobicContact CG-CG 3.4Å; Y437-M503 VanDerWaalsContact CG-CG 3.4Å; Y437-M503 HydrophobicContact CG-SD 3.69Å; D499-M503 WeakPolarHBondContact O-CB 3.13Å; D499-M503 WeakPolarHBondContact O-CG 3.03Å; D499-M503 PolarHBondContact O-N 3.45Å; M503-M505 PolarHBondContact O-N 3.34Å; M503-Y507 HydrophobicContact CE-CD1 4.35Å; M503-Y507 HydrophobicContact CE-CE1 3.74Å; M503-Y507 HydrophobicContact CE-CE2 4.02Å; M503-L510 HydrophobicContact CE-CD1 4.06Å; M503-L510 HydrophobicContact SD-CD1 3.99Å; M503-H550 PolarHBondContact O-NE2 3.38Å
504G88.4Confident84.2Confident40 Ų4043.8 Ų43.841%0.41225%0.25SC..THydrogen-bonded Turntrans69.620.5-172.500000113.5E500 S501 D502E500-G504 PolarHBondContact O-N 3.39Å; S501-G504 PolarHBondContact O-N 3.49Å; D502-G504 PolarHBondContact O-N 3.36Å
505M90.4Very high86.2Confident8 Ų841.4 Ų41.44%0.03923%0.234CC..SBendtrans-151.2143.8-178.7-66.8-163.817600111.3E500 M503 L510 I513 K547 H550 F551E500-M505 WeakPolarHBondContact CA-O 3.23Å; E500-M505 PolarHBondContact O-N 3.46Å; E500-M505 VanDerWaalsContact O-N 3.17Å; M503-M505 PolarHBondContact O-N 3.34Å; M505-L510 HydrophobicContact CB-CD2 4.05Å; M505-L510 HydrophobicContact CB-CG 4.12Å; M505-L510 HydrophobicContact CG-CD2 4.48Å; M505-L510 HydrophobicContact SD-CD2 3.68Å; M505-I513 HydrophobicContact CE-CD1 4.47Å; M505-I513 HydrophobicContact SD-CD1 3.93Å; M505-K547 HydrophobicContact CE-CB 4.23Å; M505-K547 WeakPolarHBondContact CE-O 3.38Å; M505-H550 HydrophobicContact CE-CB 4.07Å; M505-F551 HydrophobicContact CE-CB 3.49Å; M505-F551 VanDerWaalsContact CE-CB 3.49Å; M505-F551 HydrophobicContact SD-CB 4.06Å; M505-F551 HydrophobicContact SD-CD2 4.42Å
506M92.6Very high88.1Confident90 Ų9038.7 Ų38.744%0.44322%0.22SC..  trans-78.1149.7172.4-58.9-175.5-66.600110.8E500 S508 E509 L510E500-M506 VanDerWaalsContact OE1-CA 3.32Å; E500-M506 WeakPolarHBondContact OE1-CA 3.45Å; M506-S508 PolarHBondContact O-N 3Å; M506-E509 HydrophobicContact CB-CG 4.1Å; M506-E509 HydrophobicContact CE-CG 3.8Å; M506-E509 PolarHBondContact N-OE2 2.9Å; M506-E509 WeakPolarHBondContact O-CB 3.45Å; M506-E509 PolarHBondContact O-N 2.99Å; M506-L510 PolarHBondContact O-N 3.26Å
507Y91.8Very high90Very high1 Ų136.3 Ų36.30%0.00420%0.203CC..Hα-helixtrans-59.2-35.2174.8-74.7-74.1000112.2D431 E432 K456 E500 M503 E509 L510 S511D431-Y507 HydrophobicContact CB-CD1 3.98Å; D431-Y507 HydrophobicContact CB-CE1 4.36Å; E432-Y507 HydrophobicContact CG-CE1 4.12Å; E432-Y507 PolarHBondContact OE1-OH 3.37Å; K456-Y507 HydrophobicContact CB-CD1 3.43Å; K456-Y507 VanDerWaalsContact CB-CD1 3.43Å; K456-Y507 HydrophobicContact CB-CD2 4.41Å; K456-Y507 HydrophobicContact CB-CE1 3.89Å; K456-Y507 HydrophobicContact CB-CG 3.73Å; K456-Y507 HydrophobicContact CD-CD1 4.19Å; K456-Y507 HydrophobicContact CD-CE1 3.78Å; K456-Y507 HydrophobicContact CD-CE2 4.25Å; K456-Y507 HydrophobicContact CG-CD1 3.67Å; K456-Y507 HydrophobicContact CG-CD2 3.89Å; K456-Y507 HydrophobicContact CG-CE1 3.79Å; K456-Y507 HydrophobicContact CG-CE2 4.02Å; K456-Y507 HydrophobicContact CG-CG 3.72Å; E500-Y507 HydrophobicContact CG-CD2 3.58Å; E500-Y507 HydrophobicContact CG-CE2 3.74Å; E500-Y507 VanDerWaalsContact OE1-CD2 3.28Å; E500-Y507 WeakPolarHBondContact OE1-CD2 3.34Å; E500-Y507 PolarHBondContact OE1-N 3.04Å; M503-Y507 HydrophobicContact CE-CD1 4.35Å; M503-Y507 HydrophobicContact CE-CE1 3.74Å; M503-Y507 HydrophobicContact CE-CE2 4.02Å; Y507-E509 VanDerWaalsContact C-N 3.3Å; Y507-E509 PolarHBondContact O-N 3.3Å; Y507-L510 HydrophobicContact CD1-CD1 4.43Å; Y507-L510 PolarHBondContact O-N 2.95Å; Y507-S511 PolarHBondContact O-N 3.18Å; Y507-S511 PolarHBondContact O-OG 3.39Å
508S92Very high91.4Very high60 Ų6033.8 Ų33.842%0.4219%0.191SC..Hα-helixtrans-61.5-37.1175.2570000112.7M506M506-S508 PolarHBondContact O-N 3Å
509E94.3Very high92.2Very high14 Ų1434.6 Ų34.67%0.06519%0.192CC..Hα-helixtrans-71.1-42.3174.5-61.7175.3136.200111M506 Y507 S511 V512 I513 W535 K547M506-E509 HydrophobicContact CB-CG 4.1Å; M506-E509 HydrophobicContact CE-CG 3.8Å; M506-E509 PolarHBondContact N-OE2 2.9Å; M506-E509 WeakPolarHBondContact O-CB 3.45Å; M506-E509 PolarHBondContact O-N 2.99Å; Y507-E509 VanDerWaalsContact C-N 3.3Å; Y507-E509 PolarHBondContact O-N 3.3Å; E509-S511 PolarHBondContact O-N 3.07Å; E509-V512 PolarHBondContact O-N 3.41Å; E509-I513 WeakPolarHBondContact O-CG1 3.49Å; E509-I513 PolarHBondContact O-N 3.47Å; E509-W535 HydrophobicContact CB-CH2 4.13Å; E509-W535 HydrophobicContact CB-CZ2 4.13Å; E509-W535 HydrophobicContact CG-CH2 4.31Å; E509-W535 HydrophobicContact CG-CZ2 4.19Å; E509-K547 WeakPolarHBondContact OE1-CE 3.41Å; E509-K547 IonicContact OE1-NZ 2.7Å; E509-K547 PolarHBondContact OE1-NZ 3.49Å; E509-K547 IonicContact OE2-NZ 3.73Å; E509-K547 PolarHBondContact OE2-NZ 3.43Å
510L94.5Very high92.9Very high1 Ų136.5 Ų36.51%0.00521%0.207CC..Hα-helixtrans-61.6-41.9-179.4-71.5178.7000112.5D431 T435 M503 M505 M506 Y507 V512 I513 G514 F551D431-L510 HydrophobicContact CB-CB 4.33Å; D431-L510 HydrophobicContact CB-CD1 4.39Å; T435-L510 HydrophobicContact CG2-CD1 3.85Å; T435-L510 HydrophobicContact CG2-CD2 3.48Å; T435-L510 VanDerWaalsContact CG2-CD2 3.48Å; T435-L510 HydrophobicContact CG2-CG 4.32Å; M503-L510 HydrophobicContact CE-CD1 4.06Å; M503-L510 HydrophobicContact SD-CD1 3.99Å; M505-L510 HydrophobicContact CB-CD2 4.05Å; M505-L510 HydrophobicContact CB-CG 4.12Å; M505-L510 HydrophobicContact CG-CD2 4.48Å; M505-L510 HydrophobicContact SD-CD2 3.68Å; M506-L510 PolarHBondContact O-N 3.26Å; Y507-L510 HydrophobicContact CD1-CD1 4.43Å; Y507-L510 PolarHBondContact O-N 2.95Å; L510-V512 VanDerWaalsContact C-N 3.31Å; L510-V512 PolarHBondContact O-N 3.12Å; L510-I513 PolarHBondContact O-N 3.26Å; L510-G514 PolarHBondContact O-N 3.11Å; L510-F551 HydrophobicContact CD2-CD2 4.29Å
511S93.1Very high93.5Very high4 Ų440.9 Ų40.93%0.02823%0.225CC..Hα-helixtrans-64.7-36177.1-55.50000112.1D431 Y507 E509 R515D431-S511 PolarHBondContact OD1-OG 2.83Å; Y507-S511 PolarHBondContact O-N 3.18Å; Y507-S511 PolarHBondContact O-OG 3.39Å; E509-S511 PolarHBondContact O-N 3.07Å; S511-R515 WeakPolarHBondContact O-CG 3.2Å; S511-R515 PolarHBondContact O-N 2.86Å; S511-R515 VanDerWaalsContact O-N 3.14Å; S511-R515 PolarHBondContact O-NE 3.25Å
512V95.9Very high94.2Very high35 Ų3537.8 Ų37.821%0.21220%0.203CC..Hα-helixtrans-65.3-48.9173.4173.80000110.7E509 L510 G514 R515 L516 L531 L534 W535E509-V512 PolarHBondContact O-N 3.41Å; L510-V512 VanDerWaalsContact C-N 3.31Å; L510-V512 PolarHBondContact O-N 3.12Å; V512-G514 VanDerWaalsContact C-N 3.34Å; V512-G514 PolarHBondContact O-N 2.88Å; V512-R515 PolarHBondContact O-N 3.17Å; V512-L516 HydrophobicContact CG1-CD1 4.21Å; V512-L516 HydrophobicContact CG1-CG 4.47Å; V512-L516 WeakPolarHBondContact O-CG 3.38Å; V512-L516 PolarHBondContact O-N 3.24Å; V512-L531 HydrophobicContact CG1-CD2 4.08Å; V512-L534 HydrophobicContact CG1-CD2 3.63Å; V512-W535 HydrophobicContact CG1-CZ2 4.37Å
513I96.8Very high95Very high0 Ų035 Ų350%020%0.195CC..Hα-helixtrans-60.1-43.7178.7-73.6171.5000111.1M505 E509 L510 L516 R517 M527 L531 W535 F551M505-I513 HydrophobicContact CE-CD1 4.47Å; M505-I513 HydrophobicContact SD-CD1 3.93Å; E509-I513 WeakPolarHBondContact O-CG1 3.49Å; E509-I513 PolarHBondContact O-N 3.47Å; L510-I513 PolarHBondContact O-N 3.26Å; I513-L516 PolarHBondContact O-N 3.07Å; I513-R517 VanDerWaalsContact O-CB 3.3Å; I513-R517 WeakPolarHBondContact O-CB 3.47Å; I513-R517 PolarHBondContact O-N 3.12Å; I513-M527 HydrophobicContact CB-SD 4.46Å; I513-M527 HydrophobicContact CG1-SD 4.25Å; I513-M527 HydrophobicContact CG2-CE 3.88Å; I513-M527 HydrophobicContact CG2-SD 3.86Å; I513-L531 HydrophobicContact CG1-CD1 4.36Å; I513-W535 HydrophobicContact CD1-CH2 4.1Å; I513-W535 HydrophobicContact CG1-CH2 4.18Å; I513-F551 HydrophobicContact CD1-CB 4.44Å; I513-F551 HydrophobicContact CD1-CG 4.46Å; I513-F551 HydrophobicContact CG2-CD1 3.52Å; I513-F551 HydrophobicContact CG2-CD2 3.62Å; I513-F551 HydrophobicContact CG2-CE1 3.39Å; I513-F551 HydrophobicContact CG2-CE2 3.48Å; I513-F551 VanDerWaalsContact CG2-CE2 3.48Å; I513-F551 HydrophobicContact CG2-CG 3.64Å; I513-F551 HydrophobicContact CG2-CZ 3.37Å
514G96.8Very high95.5Very high0 Ų034.5 Ų34.50%019%0.193CC..Hα-helixtrans-58.3-48.7177.300000111.9L510 V512 R517 K518L510-G514 PolarHBondContact O-N 3.11Å; V512-G514 VanDerWaalsContact C-N 3.34Å; V512-G514 PolarHBondContact O-N 2.88Å; G514-R517 PolarHBondContact O-N 3.1Å; G514-K518 WeakPolarHBondContact O-CB 3.29Å; G514-K518 PolarHBondContact O-N 2.94Å
515R97.2Very high96Very high99 Ų9936.1 Ų36.137%0.37419%0.189SC..Hα-helixtrans-61.8-45.3174.5-72.2-173.7-82.4-99.91.5112.2S511 V512 R517 K518 I519 S520 Y574S511-R515 WeakPolarHBondContact O-CG 3.2Å; S511-R515 PolarHBondContact O-N 2.86Å; S511-R515 VanDerWaalsContact O-N 3.14Å; S511-R515 PolarHBondContact O-NE 3.25Å; V512-R515 PolarHBondContact O-N 3.17Å; R515-R517 VanDerWaalsContact C-N 3.35Å; R515-R517 PolarHBondContact O-N 2.82Å; R515-K518 PolarHBondContact O-N 2.87Å; R515-I519 HydrophobicContact CB-CD1 4.06Å; R515-I519 HydrophobicContact CG-CD1 3.77Å; R515-I519 WeakPolarHBondContact O-CA 3.39Å; R515-I519 VanDerWaalsContact O-CB 3.25Å; R515-I519 WeakPolarHBondContact O-CB 3.48Å; R515-I519 PolarHBondContact O-N 2.86Å; R515-S520 PolarHBondContact O-N 2.83Å; R515-S520 VanDerWaalsContact O-N 3.11Å; R515-Y574 HydrophobicContact CG-CD1 3.66Å; R515-Y574 HydrophobicContact CG-CE1 4.09Å; R515-Y574 HydrophobicContact CG-CG 4.11Å
516L98.3Very high96.4Very high19 Ų1938.1 Ų38.110%0.09920%0.204CC..Hα-helixtrans-60.5-43.9176.6-72.8-179.6000112.2V512 I513 S520 K521 C522 M527 K530 L531V512-L516 HydrophobicContact CG1-CD1 4.21Å; V512-L516 HydrophobicContact CG1-CG 4.47Å; V512-L516 WeakPolarHBondContact O-CG 3.38Å; V512-L516 PolarHBondContact O-N 3.24Å; I513-L516 PolarHBondContact O-N 3.07Å; L516-S520 CarbonylContact O-C 3.59Å; L516-S520 VanDerWaalsContact O-C 3.31Å; L516-S520 WeakPolarHBondContact O-CB 3.37Å; L516-K521 PolarHBondContact O-N 2.85Å; L516-C522 HydrophobicContact CB-CB 4.5Å; L516-C522 VanDerWaalsContact O-CB 3.31Å; L516-C522 WeakPolarHBondContact O-CB 3.38Å; L516-C522 PolarHBondContact O-N 2.98Å; L516-M527 HydrophobicContact CB-CE 4.19Å; L516-M527 HydrophobicContact CB-CG 4.45Å; L516-M527 HydrophobicContact CD1-CG 4.09Å; L516-K530 HydrophobicContact CD1-CB 4.49Å; L516-K530 HydrophobicContact CD2-CD 3.75Å; L516-L531 HydrophobicContact CD1-CD1 4.33Å; L516-L531 HydrophobicContact CD1-CD2 3.5Å; L516-L531 VanDerWaalsContact CD1-CD2 3.5Å; L516-L531 HydrophobicContact CD1-CG 3.74Å
517R98.4Very high96.7Very high3 Ų333.9 Ų33.91%0.01118%0.183CC..Hα-helixtrans-64.1-50.3178.7178.1-170.5164.6-79.8-5.9111.9I513 G514 R515 K521 M527 Y555 D582I513-R517 VanDerWaalsContact O-CB 3.3Å; I513-R517 WeakPolarHBondContact O-CB 3.47Å; I513-R517 PolarHBondContact O-N 3.12Å; G514-R517 PolarHBondContact O-N 3.1Å; R515-R517 VanDerWaalsContact C-N 3.35Å; R515-R517 PolarHBondContact O-N 2.82Å; R517-K521 WeakPolarHBondContact O-CA 3.27Å; R517-M527 HydrophobicContact CB-CE 3.87Å; R517-Y555 VanDerWaalsContact NH2-CZ 3.32Å; R517-Y555 PolarHBondContact NH2-OH 3.01Å; R517-D582 IonicContact CZ-OD2 2.83Å; R517-D582 IonicContact NH1-OD1 3.92Å; R517-D582 IonicContact NH1-OD2 3.43Å; R517-D582 PolarHBondContact NH1-OD2 2.85Å; R517-D582 IonicContact NH2-OD1 2.74Å; R517-D582 IonicContact NH2-OD2 2.72Å; R517-D582 PolarHBondContact NH2-OD2 2.8Å
518K97.8Very high97Very high26 Ų2633.8 Ų33.811%0.11318%0.183CC..Hα-helixtrans-96.3-40.3-168-174.954171.8-178.20113.8G514 R515 K521 F581 D582G514-K518 WeakPolarHBondContact O-CB 3.29Å; G514-K518 PolarHBondContact O-N 2.94Å; R515-K518 PolarHBondContact O-N 2.87Å; K518-K521 WeakPolarHBondContact O-CD 3.42Å; K518-K521 VanDerWaalsContact O-CE 3.31Å; K518-K521 WeakPolarHBondContact O-CE 3.33Å; K518-K521 PolarHBondContact O-NZ 2.92Å; K518-F581 HydrophobicContact CD-CE1 4.41Å; K518-F581 HydrophobicContact CG-CE1 4.18Å; K518-F581 PolarHBondContact NZ-O 3.49Å; K518-D582 HydrophobicContact CD-CB 4.44Å; K518-D582 WeakPolarHBondContact CD-OD1 3.36Å; K518-D582 VanDerWaalsContact NZ-CA 3.34Å; K518-D582 IonicContact NZ-OD1 3.83Å; K518-D582 PolarHBondContact NZ-OD1 3.27Å
519I96.6Very high97.2Very high72 Ų7232.9 Ų32.937%0.36918%0.176SC..THydrogen-bonded Turntrans-84-56.7179.6-54.8177.2000109.2R515 K521 S573R515-I519 HydrophobicContact CB-CD1 4.06Å; R515-I519 HydrophobicContact CG-CD1 3.77Å; R515-I519 WeakPolarHBondContact O-CA 3.39Å; R515-I519 VanDerWaalsContact O-CB 3.25Å; R515-I519 WeakPolarHBondContact O-CB 3.48Å; R515-I519 PolarHBondContact O-N 2.86Å; I519-K521 PolarHBondContact O-N 2.82Å; I519-K521 PolarHBondContact O-NZ 3.4Å; I519-S573 WeakPolarHBondContact CD1-OG 3.49Å
520S97.6Very high97.4Very high60 Ų6037.3 Ų37.342%0.4220%0.195SC..SBendtrans-79.22.3-179.3-47.50000114.2R515 L516 C522R515-S520 PolarHBondContact O-N 2.83Å; R515-S520 VanDerWaalsContact O-N 3.11Å; L516-S520 CarbonylContact O-C 3.59Å; L516-S520 VanDerWaalsContact O-C 3.31Å; L516-S520 WeakPolarHBondContact O-CB 3.37Å; S520-C522 PolarHBondContact O-N 3.35Å; S520-C522 VanDerWaalsContact O-N 3.15Å; S520-C522 PolarHBondContact O-SG 3.06Å; S520-C522 VanDerWaalsContact O-SG 3.41Å
521K97.8Very high97.6Very high149 Ų14937.2 Ų37.265%0.64819%0.194SC*.  trans54.932.4175-50.5-62-179.8-74.90114L516 R517 K518 I519L516-K521 PolarHBondContact O-N 2.85Å; R517-K521 WeakPolarHBondContact O-CA 3.27Å; K518-K521 WeakPolarHBondContact O-CD 3.42Å; K518-K521 VanDerWaalsContact O-CE 3.31Å; K518-K521 WeakPolarHBondContact O-CE 3.33Å; K518-K521 PolarHBondContact O-NZ 2.92Å; I519-K521 PolarHBondContact O-N 2.82Å; I519-K521 PolarHBondContact O-NZ 3.4Å
522C98.5Very high97.7Very high9 Ų938.2 Ų38.26%0.06120%0.199CC..  trans-79.6134.1-176.8-64.50000112.4L516 S520 S526 M527L516-C522 HydrophobicContact CB-CB 4.5Å; L516-C522 VanDerWaalsContact O-CB 3.31Å; L516-C522 WeakPolarHBondContact O-CB 3.38Å; L516-C522 PolarHBondContact O-N 2.98Å; S520-C522 PolarHBondContact O-N 3.35Å; S520-C522 VanDerWaalsContact O-N 3.15Å; S520-C522 PolarHBondContact O-SG 3.06Å; S520-C522 VanDerWaalsContact O-SG 3.41Å; C522-S526 WeakPolarHBondContact CA-OG 3.45Å; C522-M527 HydrophobicContact CB-CB 4Å
523G98.3Very high97.7Very high28 Ų2843 Ų4329%0.28922%0.219SC..  trans-88.1-171.8161.400000110.9F525 S526 M527G523-F525 PolarHBondContact O-N 2.94Å; G523-S526 PolarHBondContact N-OG 2.92Å; G523-S526 PolarHBondContact O-OG 3.45Å; G523-M527 WeakPolarHBondContact O-CB 3.15Å; G523-M527 PolarHBondContact O-N 3.48Å
524P98.6Very high97.6Very high7 Ų747.9 Ų47.95%0.04524%0.244CC..Hα-helixtrans-56.9-51.9-175.2-21.529000113.5M527 F528 V548 F552 W592 Q595 F596 I599P524-M527 PolarHBondContact O-N 3.31Å; P524-F528 PolarHBondContact O-N 3.49Å; P524-V548 HydrophobicContact CB-CG1 4.4Å; P524-V548 WeakPolarHBondContact O-CG1 3.46Å; P524-F552 VanDerWaalsContact CA-CE2 3.45Å; P524-F552 HydrophobicContact CB-CD2 3.87Å; P524-F552 HydrophobicContact CB-CE2 4.05Å; P524-F552 HydrophobicContact CB-CG 4.19Å; P524-F552 HydrophobicContact CG-CB 4.4Å; P524-F552 HydrophobicContact CG-CD1 3.79Å; P524-F552 HydrophobicContact CG-CD2 3.9Å; P524-F552 HydrophobicContact CG-CE1 3.96Å; P524-F552 HydrophobicContact CG-CE2 4.08Å; P524-F552 HydrophobicContact CG-CG 3.76Å; P524-F552 HydrophobicContact CG-CZ 4.11Å; P524-W592 HydrophobicContact CG-CD2 4.27Å; P524-W592 HydrophobicContact CG-CE3 3.8Å; P524-W592 HydrophobicContact CG-CZ3 4.16Å; P524-Q595 HydrophobicContact CB-CB 3.99Å; P524-Q595 HydrophobicContact CG-CB 3.89Å; P524-Q595 HydrophobicContact CG-CG 4.16Å; P524-F596 HydrophobicContact CB-CD1 4.36Å; P524-F596 HydrophobicContact CB-CE1 4.11Å; P524-F596 HydrophobicContact CG-CE1 4.46Å; P524-I599 HydrophobicContact CB-CD1 4.21Å
525F98.6Very high97.6Very high74 Ų7449.3 Ų49.333%0.32525%0.25SC..Hα-helixtrans-65.8-48-176.9-176.3-105.5000112.7G523 M527 F528 C529 C598 I599 Q602G523-F525 PolarHBondContact O-N 2.94Å; F525-M527 VanDerWaalsContact C-N 3.28Å; F525-M527 PolarHBondContact O-N 3.04Å; F525-F528 WeakPolarHBondContact O-CB 3.26Å; F525-F528 PolarHBondContact O-N 2.79Å; F525-C529 PolarHBondContact O-N 2.94Å; F525-C529 PolarHBondContact O-SG 3.22Å; F525-C529 VanDerWaalsContact O-SG 3.32Å; F525-C598 HydrophobicContact CD2-CB 3.7Å; F525-C598 HydrophobicContact CE2-CB 4.08Å; F525-C598 WeakPolarHBondContact CE2-O 3.49Å; F525-C598 HydrophobicContact CG-CB 4.25Å; F525-I599 HydrophobicContact CB-CG1 4.47Å; F525-I599 HydrophobicContact CD2-CG1 3.93Å; F525-Q602 HydrophobicContact CE2-CB 3.95Å; F525-Q602 HydrophobicContact CE2-CG 4.35Å; F525-Q602 HydrophobicContact CZ-CB 4.49Å
526S98.5Very high97.5Very high50 Ų5052.9 Ų52.935%0.3526%0.263SS..Hα-helixtrans-67.2-29.8179.453.40000113C522 G523 K530C522-S526 WeakPolarHBondContact CA-OG 3.45Å; G523-S526 PolarHBondContact N-OG 2.92Å; G523-S526 PolarHBondContact O-OG 3.45Å; S526-K530 WeakPolarHBondContact O-CG 3.22Å; S526-K530 PolarHBondContact O-N 2.92Å
527M98.6Very high97.3Very high0 Ų058.2 Ų58.20%029%0.292CS..Hα-helixtrans-66.6-46.7171.3-174.7-179.4-68.100111.1I513 L516 R517 C522 G523 P524 F525 C529 K530 L531 V548 F551 F552I513-M527 HydrophobicContact CB-SD 4.46Å; I513-M527 HydrophobicContact CG1-SD 4.25Å; I513-M527 HydrophobicContact CG2-CE 3.88Å; I513-M527 HydrophobicContact CG2-SD 3.86Å; L516-M527 HydrophobicContact CB-CE 4.19Å; L516-M527 HydrophobicContact CB-CG 4.45Å; L516-M527 HydrophobicContact CD1-CG 4.09Å; R517-M527 HydrophobicContact CB-CE 3.87Å; C522-M527 HydrophobicContact CB-CB 4Å; G523-M527 WeakPolarHBondContact O-CB 3.15Å; G523-M527 PolarHBondContact O-N 3.48Å; P524-M527 PolarHBondContact O-N 3.31Å; F525-M527 VanDerWaalsContact C-N 3.28Å; F525-M527 PolarHBondContact O-N 3.04Å; M527-C529 PolarHBondContact O-N 3.4Å; M527-K530 PolarHBondContact O-N 3.39Å; M527-L531 HydrophobicContact CG-CD1 3.65Å; M527-L531 HydrophobicContact CG-CG 4.19Å; M527-L531 WeakPolarHBondContact O-CB 3.27Å; M527-L531 WeakPolarHBondContact O-CG 3.48Å; M527-L531 PolarHBondContact O-N 3.41Å; M527-L531 HydrophobicContact SD-CD1 4.24Å; M527-V548 HydrophobicContact CG-CG2 4.23Å; M527-V548 HydrophobicContact SD-CG2 4.38Å; M527-F551 HydrophobicContact CE-CE1 4.27Å; M527-F551 HydrophobicContact SD-CD1 4.39Å; M527-F552 HydrophobicContact CB-CE2 4.33Å; M527-F552 HydrophobicContact CE-CE2 3.65Å; M527-F552 HydrophobicContact CE-CZ 3.77Å; M527-F552 HydrophobicContact SD-CE2 3.64Å; M527-F552 HydrophobicContact SD-CZ 4.37Å
528F98.5Very high97.1Very high0 Ų063.9 Ų63.90%033%0.327CS..Hα-helixtrans-54-52.5173.7165.6-104.5000111.5P524 F525 K530 L531 I532 P541 V544 A545 V548 I599 Q602 I603 M606P524-F528 PolarHBondContact O-N 3.49Å; F525-F528 WeakPolarHBondContact O-CB 3.26Å; F525-F528 PolarHBondContact O-N 2.79Å; F528-K530 PolarHBondContact O-N 3.06Å; F528-K530 VanDerWaalsContact O-N 3.15Å; F528-L531 PolarHBondContact O-N 2.87Å; F528-L531 VanDerWaalsContact O-N 3.09Å; F528-I532 HydrophobicContact CD2-CG2 3.79Å; F528-I532 HydrophobicContact CE1-CG2 4.31Å; F528-I532 HydrophobicContact CE2-CG2 3.33Å; F528-I532 HydrophobicContact CG-CG2 4.44Å; F528-I532 HydrophobicContact CZ-CG2 3.64Å; F528-I532 WeakPolarHBondContact O-CG2 3.43Å; F528-I532 PolarHBondContact O-N 2.65Å; F528-P541 WeakPolarHBondContact CE2-O 3.43Å; F528-V544 HydrophobicContact CD2-CB 4.5Å; F528-V544 HydrophobicContact CD2-CG1 4Å; F528-V544 HydrophobicContact CE2-CG1 4.49Å; F528-A545 HydrophobicContact CD2-CB 3.98Å; F528-A545 HydrophobicContact CE2-CB 3.83Å; F528-V548 HydrophobicContact CB-CG1 4.42Å; F528-V548 HydrophobicContact CB-CG2 4.36Å; F528-I599 HydrophobicContact CB-CD1 4.07Å; F528-I599 HydrophobicContact CB-CG1 4.04Å; F528-I599 HydrophobicContact CD1-CB 4.5Å; F528-I599 HydrophobicContact CD1-CG1 4.2Å; F528-I599 HydrophobicContact CD1-CG2 4.07Å; F528-I599 HydrophobicContact CD2-CG2 3.94Å; F528-I599 HydrophobicContact CE1-CG2 4.24Å; F528-I599 HydrophobicContact CE2-CG2 4.13Å; F528-I599 HydrophobicContact CG-CG1 4.14Å; F528-I599 HydrophobicContact CG-CG2 3.91Å; F528-I599 HydrophobicContact CZ-CG2 4.28Å; F528-Q602 HydrophobicContact CE1-CB 4.06Å; F528-Q602 HydrophobicContact CE1-CG 3.94Å; F528-I603 HydrophobicContact CE2-CD1 4.3Å; F528-I603 HydrophobicContact CE2-CG1 4.23Å; F528-I603 HydrophobicContact CZ-CD1 4.27Å; F528-I603 HydrophobicContact CZ-CG1 3.74Å; F528-M606 HydrophobicContact CE1-CE 4.05Å; F528-M606 HydrophobicContact CZ-CE 3.79Å
529C97.8Very high96.9Very high41 Ų4164 Ų6428%0.27733%0.328SS..Hα-helixtrans-58.4-30.2179.3-63.80000113.8F525 M527 I532 H533F525-C529 PolarHBondContact O-N 2.94Å; F525-C529 PolarHBondContact O-SG 3.22Å; F525-C529 VanDerWaalsContact O-SG 3.32Å; M527-C529 PolarHBondContact O-N 3.4Å; C529-I532 VanDerWaalsContact O-CG1 3.25Å; C529-I532 WeakPolarHBondContact O-CG1 3.32Å; C529-H533 PolarHBondContact O-CD2 3.19Å
530K97.7Very high96.8Very high106 Ų10662.8 Ų62.846%0.46133%0.326SS..Hα-helixtrans-78.4-43.7174.7-74.6-177.6178.8-70.20112L516 S526 M527 F528 H533 L534L516-K530 HydrophobicContact CD1-CB 4.49Å; L516-K530 HydrophobicContact CD2-CD 3.75Å; S526-K530 WeakPolarHBondContact O-CG 3.22Å; S526-K530 PolarHBondContact O-N 2.92Å; M527-K530 PolarHBondContact O-N 3.39Å; F528-K530 PolarHBondContact O-N 3.06Å; F528-K530 VanDerWaalsContact O-N 3.15Å; K530-H533 PolarHBondContact O-N 3.45Å; K530-L534 PolarHBondContact O-N 3.16Å
531L97.8Very high96.8Very high0 Ų061.9 Ų61.90%032%0.319CS..Hα-helixtrans-71.5-29.7-174.4-71.1176.8000113.1V512 I513 L516 M527 F528 H533 L534 W535 V544 V548V512-L531 HydrophobicContact CG1-CD2 4.08Å; I513-L531 HydrophobicContact CG1-CD1 4.36Å; L516-L531 HydrophobicContact CD1-CD1 4.33Å; L516-L531 HydrophobicContact CD1-CD2 3.5Å; L516-L531 VanDerWaalsContact CD1-CD2 3.5Å; L516-L531 HydrophobicContact CD1-CG 3.74Å; M527-L531 HydrophobicContact CG-CD1 3.65Å; M527-L531 HydrophobicContact CG-CG 4.19Å; M527-L531 WeakPolarHBondContact O-CB 3.27Å; M527-L531 WeakPolarHBondContact O-CG 3.48Å; M527-L531 PolarHBondContact O-N 3.41Å; M527-L531 HydrophobicContact SD-CD1 4.24Å; F528-L531 PolarHBondContact O-N 2.87Å; F528-L531 VanDerWaalsContact O-N 3.09Å; L531-H533 PolarHBondContact O-N 2.84Å; L531-L534 HydrophobicContact CD2-CB 4.5Å; L531-L534 HydrophobicContact CD2-CD2 4.03Å; L531-L534 PolarHBondContact O-N 3.27Å; L531-W535 HydrophobicContact CB-CD2 4.4Å; L531-W535 HydrophobicContact CB-CE3 4.04Å; L531-W535 HydrophobicContact CB-CZ3 4.4Å; L531-W535 HydrophobicContact CD1-CE3 4.18Å; L531-W535 HydrophobicContact CD1-CH2 3.88Å; L531-W535 HydrophobicContact CD1-CZ2 4.5Å; L531-W535 HydrophobicContact CD1-CZ3 3.69Å; L531-W535 HydrophobicContact CD2-CD2 3.86Å; L531-W535 HydrophobicContact CD2-CE3 4.04Å; L531-W535 HydrophobicContact CD2-CH2 3.95Å; L531-W535 HydrophobicContact CD2-CZ2 3.74Å; L531-W535 HydrophobicContact CD2-CZ3 4.1Å; L531-W535 HydrophobicContact CG-CE3 4.32Å; L531-W535 HydrophobicContact CG-CH2 4.49Å; L531-W535 HydrophobicContact CG-CZ3 4.29Å; L531-W535 WeakPolarHBondContact O-CB 3.45Å; L531-W535 PolarHBondContact O-N 3.25Å; L531-V544 HydrophobicContact CB-CG1 3.44Å; L531-V544 VanDerWaalsContact CB-CG1 3.44Å; L531-V548 HydrophobicContact CD1-CG2 3.68Å
532I96.7Very high96.7Very high25 Ų2559.4 Ų59.413%0.12831%0.312CS..Hα-helixtrans-60.1-26.9173.560.2173.6000112.7F528 C529 R536 P541 V544 M606F528-I532 HydrophobicContact CD2-CG2 3.79Å; F528-I532 HydrophobicContact CE1-CG2 4.31Å; F528-I532 HydrophobicContact CE2-CG2 3.33Å; F528-I532 HydrophobicContact CG-CG2 4.44Å; F528-I532 HydrophobicContact CZ-CG2 3.64Å; F528-I532 WeakPolarHBondContact O-CG2 3.43Å; F528-I532 PolarHBondContact O-N 2.65Å; C529-I532 VanDerWaalsContact O-CG1 3.25Å; C529-I532 WeakPolarHBondContact O-CG1 3.32Å; I532-R536 VanDerWaalsContact O-CB 3.23Å; I532-R536 WeakPolarHBondContact O-CB 3.3Å; I532-P541 HydrophobicContact CG2-CB 4.19Å; I532-V544 HydrophobicContact CG2-CB 4.2Å; I532-V544 HydrophobicContact CG2-CG1 4.05Å; I532-M606 HydrophobicContact CD1-CE 3.63Å
533H95.8Very high96.6Very high134 Ų13462.9 Ų62.962%0.6233%0.327SS*.Hα-helixtrans-89.7-41.7175.6-63.8-54.3000111.4C529 K530 L531 W535C529-H533 PolarHBondContact O-CD2 3.19Å; K530-H533 PolarHBondContact O-N 3.45Å; L531-H533 PolarHBondContact O-N 2.84Å; H533-W535 VanDerWaalsContact C-N 3.35Å; H533-W535 PolarHBondContact O-N 2.79Å
534L95.1Very high96.6Very high104 Ų10461.6 Ų61.655%0.54531%0.313SS..Hα-helixtrans-67.9-34.3-178.1-170.865.7000112.9V512 K530 L531V512-L534 HydrophobicContact CG1-CD2 3.63Å; K530-L534 PolarHBondContact O-N 3.16Å; L531-L534 HydrophobicContact CD2-CB 4.5Å; L531-L534 HydrophobicContact CD2-CD2 4.03Å; L531-L534 PolarHBondContact O-N 3.27Å
535W96.5Very high96.6Very high30 Ų3061.4 Ų61.411%0.11431%0.313CS..THydrogen-bonded Turntrans-108.714.9-178.1-63-21.6000113E509 V512 I513 L531 H533 D537 V538 L539 V544 K547E509-W535 HydrophobicContact CB-CH2 4.13Å; E509-W535 HydrophobicContact CB-CZ2 4.13Å; E509-W535 HydrophobicContact CG-CH2 4.31Å; E509-W535 HydrophobicContact CG-CZ2 4.19Å; V512-W535 HydrophobicContact CG1-CZ2 4.37Å; I513-W535 HydrophobicContact CD1-CH2 4.1Å; I513-W535 HydrophobicContact CG1-CH2 4.18Å; L531-W535 HydrophobicContact CB-CD2 4.4Å; L531-W535 HydrophobicContact CB-CE3 4.04Å; L531-W535 HydrophobicContact CB-CZ3 4.4Å; L531-W535 HydrophobicContact CD1-CE3 4.18Å; L531-W535 HydrophobicContact CD1-CH2 3.88Å; L531-W535 HydrophobicContact CD1-CZ2 4.5Å; L531-W535 HydrophobicContact CD1-CZ3 3.69Å; L531-W535 HydrophobicContact CD2-CD2 3.86Å; L531-W535 HydrophobicContact CD2-CE3 4.04Å; L531-W535 HydrophobicContact CD2-CH2 3.95Å; L531-W535 HydrophobicContact CD2-CZ2 3.74Å; L531-W535 HydrophobicContact CD2-CZ3 4.1Å; L531-W535 HydrophobicContact CG-CE3 4.32Å; L531-W535 HydrophobicContact CG-CH2 4.49Å; L531-W535 HydrophobicContact CG-CZ3 4.29Å; L531-W535 WeakPolarHBondContact O-CB 3.45Å; L531-W535 PolarHBondContact O-N 3.25Å; H533-W535 VanDerWaalsContact C-N 3.35Å; H533-W535 PolarHBondContact O-N 2.79Å; W535-D537 PolarHBondContact O-N 2.86Å; W535-D537 VanDerWaalsContact O-N 3.09Å; W535-V538 PolarHBondContact O-N 3.08Å; W535-L539 HydrophobicContact CB-CB 4.27Å; W535-L539 HydrophobicContact CB-CD1 4.2Å; W535-L539 HydrophobicContact CB-CG 4.47Å; W535-L539 HydrophobicContact CD2-CD1 4.09Å; W535-L539 HydrophobicContact CE3-CD1 3.61Å; W535-L539 HydrophobicContact CG-CD1 4.39Å; W535-L539 HydrophobicContact CZ3-CD1 4.23Å; W535-L539 PolarHBondContact O-N 2.93Å; W535-V544 HydrophobicContact CB-CG2 4.4Å; W535-V544 HydrophobicContact CE3-CG1 4.46Å; W535-V544 HydrophobicContact CE3-CG2 4.22Å; W535-K547 HydrophobicContact CZ3-CB 4.5Å; W535-K547 HydrophobicContact CZ3-CD 4.05Å
536R93.6Very high96.5Very high174 Ų17463.8 Ų63.866%0.65733%0.325SS*.THydrogen-bonded Turntrans-55.9-32.2-173.779.1-175.9-161.5174.23.8113.7I532 V538I532-R536 VanDerWaalsContact O-CB 3.23Å; I532-R536 WeakPolarHBondContact O-CB 3.3Å; R536-V538 VanDerWaalsContact C-N 3.33Å
537D93.9Very high96.4Very high131 Ų13163.6 Ų63.670%0.70132%0.318SS*.THydrogen-bonded Turntrans-85.6-9.5-175.4-51.5-48.3000111.9W535W535-D537 PolarHBondContact O-N 2.86Å; W535-D537 VanDerWaalsContact O-N 3.09Å
538V94.1Very high96.4Very high122 Ų12263.6 Ų63.674%0.73932%0.318SS*.THydrogen-bonded Turntrans-121.5-31.6-174-169.90000112.1W535 R536W535-V538 PolarHBondContact O-N 3.08Å; R536-V538 VanDerWaalsContact C-N 3.33Å
539L94.4Very high96.4Very high27 Ų2765.7 Ų65.714%0.14133%0.327CS..  trans-136137.7-173.2-62.6175.6000111.4W535 Q543 V544 K547W535-L539 HydrophobicContact CB-CB 4.27Å; W535-L539 HydrophobicContact CB-CD1 4.2Å; W535-L539 HydrophobicContact CB-CG 4.47Å; W535-L539 HydrophobicContact CD2-CD1 4.09Å; W535-L539 HydrophobicContact CE3-CD1 3.61Å; W535-L539 HydrophobicContact CG-CD1 4.39Å; W535-L539 HydrophobicContact CZ3-CD1 4.23Å; W535-L539 PolarHBondContact O-N 2.93Å; L539-Q543 HydrophobicContact CB-CB 4.24Å; L539-Q543 HydrophobicContact CD2-CB 4.18Å; L539-V544 HydrophobicContact CB-CG2 3.88Å; L539-V544 HydrophobicContact CD1-CG2 4.48Å; L539-K547 HydrophobicContact CD1-CD 3.8Å
540S95.5Very high96.4Very high47 Ų4766.9 Ų66.933%0.32933%0.328SS..  trans-67.8156.5169.265.20000111.7I542 Q543 V544S540-I542 PolarHBondContact O-N 3.34Å; S540-I542 VanDerWaalsContact O-N 3.12Å; S540-Q543 PolarHBondContact O-N 3.43Å; S540-Q543 WeakPolarHBondContact OG-CG 3.25Å; S540-Q543 PolarHBondContact OG-N 3.47Å; S540-Q543 PolarHBondContact OG-OE1 3.38Å; S540-V544 WeakPolarHBondContact O-CG2 3.43Å; S540-V544 PolarHBondContact O-N 2.78Å
541P96.4Very high96.4Very high41 Ų4162 Ų6227%0.26631%0.307SS..Hα-helixtrans-53.1-35.2174.9-2835.5000113.8F528 I532 V544 A545 M606F528-P541 WeakPolarHBondContact CE2-O 3.43Å; I532-P541 HydrophobicContact CG2-CB 4.19Å; P541-V544 PolarHBondContact O-N 3.05Å; P541-A545 PolarHBondContact O-N 2.99Å; P541-M606 HydrophobicContact CB-CE 4.46Å; P541-M606 HydrophobicContact CB-SD 3.63Å; P541-M606 HydrophobicContact CG-SD 3.8Å
542I96.9Very high96.4Very high97 Ų9762.3 Ų62.350%0.49731%0.308SS..Hα-helixtrans-65-46.7177.3-62.9172.5000110.9S540 V544 A545 Q546 I603S540-I542 PolarHBondContact O-N 3.34Å; S540-I542 VanDerWaalsContact O-N 3.12Å; I542-V544 VanDerWaalsContact C-N 3.33Å; I542-V544 PolarHBondContact O-N 3.37Å; I542-A545 PolarHBondContact O-N 3.23Å; I542-Q546 WeakPolarHBondContact O-CG 3.24Å; I542-Q546 PolarHBondContact O-N 2.68Å; I542-I603 HydrophobicContact CG1-CG2 4.01Å
543Q96.4Very high96.5Very high83 Ų8367.9 Ų67.939%0.38833%0.328SS..Hα-helixtrans-64-39177.4-72.1164.8-49.800111.6L539 S540 Q546 K547L539-Q543 HydrophobicContact CB-CB 4.24Å; L539-Q543 HydrophobicContact CD2-CB 4.18Å; S540-Q543 PolarHBondContact O-N 3.43Å; S540-Q543 WeakPolarHBondContact OG-CG 3.25Å; S540-Q543 PolarHBondContact OG-N 3.47Å; S540-Q543 PolarHBondContact OG-OE1 3.38Å; Q543-Q546 PolarHBondContact O-N 3.01Å; Q543-K547 PolarHBondContact O-N 3.24Å
544V97.3Very high96.6Very high0 Ų065 Ų650%032%0.315CS..Hα-helixtrans-60.8-46.7174.1177.90000110.7F528 L531 I532 W535 L539 S540 P541 I542 Q546 K547 V548F528-V544 HydrophobicContact CD2-CB 4.5Å; F528-V544 HydrophobicContact CD2-CG1 4Å; F528-V544 HydrophobicContact CE2-CG1 4.49Å; L531-V544 HydrophobicContact CB-CG1 3.44Å; L531-V544 VanDerWaalsContact CB-CG1 3.44Å; I532-V544 HydrophobicContact CG2-CB 4.2Å; I532-V544 HydrophobicContact CG2-CG1 4.05Å; W535-V544 HydrophobicContact CB-CG2 4.4Å; W535-V544 HydrophobicContact CE3-CG1 4.46Å; W535-V544 HydrophobicContact CE3-CG2 4.22Å; L539-V544 HydrophobicContact CB-CG2 3.88Å; L539-V544 HydrophobicContact CD1-CG2 4.48Å; S540-V544 WeakPolarHBondContact O-CG2 3.43Å; S540-V544 PolarHBondContact O-N 2.78Å; P541-V544 PolarHBondContact O-N 3.05Å; I542-V544 VanDerWaalsContact C-N 3.33Å; I542-V544 PolarHBondContact O-N 3.37Å; V544-Q546 VanDerWaalsContact C-N 3.35Å; V544-Q546 PolarHBondContact O-N 3.25Å; V544-K547 PolarHBondContact O-N 3.3Å; V544-V548 HydrophobicContact CG1-CG2 4.33Å; V544-V548 WeakPolarHBondContact O-CG2 3.46Å; V544-V548 PolarHBondContact O-N 3.06Å
545A97.8Very high96.7Very high4 Ų460.2 Ų60.23%0.03329%0.29CS..Hα-helixtrans-61.3-42.4177.200000112.5F528 P541 I542 K547 V548 K549 I599 I603F528-A545 HydrophobicContact CD2-CB 3.98Å; F528-A545 HydrophobicContact CE2-CB 3.83Å; P541-A545 PolarHBondContact O-N 2.99Å; I542-A545 PolarHBondContact O-N 3.23Å; A545-K547 PolarHBondContact O-N 2.92Å; A545-V548 PolarHBondContact O-N 2.72Å; A545-K549 VanDerWaalsContact O-CB 3.32Å; A545-K549 WeakPolarHBondContact O-CB 3.29Å; A545-K549 WeakPolarHBondContact O-CG 3.39Å; A545-K549 PolarHBondContact O-N 3.37Å; A545-I599 HydrophobicContact CB-CG2 3.48Å; A545-I599 VanDerWaalsContact CB-CG2 3.48Å; A545-I603 HydrophobicContact CB-CD1 3.29Å
546Q97.6Very high96.8Very high123 Ų12358.9 Ų58.958%0.57529%0.286SS*.Hα-helixtrans-58.8-47.4175.7-72.9171.7-11.900111.3I542 Q543 V544 K549 H550I542-Q546 WeakPolarHBondContact O-CG 3.24Å; I542-Q546 PolarHBondContact O-N 2.68Å; Q543-Q546 PolarHBondContact O-N 3.01Å; V544-Q546 VanDerWaalsContact C-N 3.35Å; V544-Q546 PolarHBondContact O-N 3.25Å; Q546-K549 PolarHBondContact O-N 3.07Å; Q546-H550 VanDerWaalsContact O-CB 3.29Å; Q546-H550 WeakPolarHBondContact O-CB 3.43Å; Q546-H550 PolarHBondContact O-N 3.34Å
547K97.1Very high97Very high46 Ų4653.7 Ų53.720%0.227%0.273CS..Hα-helixtrans-61.3-50176.2-76-179.3177.3-81.90111.7M505 E509 W535 L539 Q543 V544 A545 K549 H550 F551M505-K547 HydrophobicContact CE-CB 4.23Å; M505-K547 WeakPolarHBondContact CE-O 3.38Å; E509-K547 WeakPolarHBondContact OE1-CE 3.41Å; E509-K547 IonicContact OE1-NZ 2.7Å; E509-K547 PolarHBondContact OE1-NZ 3.49Å; E509-K547 IonicContact OE2-NZ 3.73Å; E509-K547 PolarHBondContact OE2-NZ 3.43Å; W535-K547 HydrophobicContact CZ3-CB 4.5Å; W535-K547 HydrophobicContact CZ3-CD 4.05Å; L539-K547 HydrophobicContact CD1-CD 3.8Å; Q543-K547 PolarHBondContact O-N 3.24Å; V544-K547 PolarHBondContact O-N 3.3Å; A545-K547 PolarHBondContact O-N 2.92Å; K547-K549 VanDerWaalsContact C-N 3.33Å; K547-K549 PolarHBondContact O-N 3.09Å; K547-H550 PolarHBondContact O-N 3.02Å; K547-F551 PolarHBondContact O-N 3.31Å
548V98.1Very high97.2Very high0 Ų048.4 Ų48.40%025%0.245CC..Hα-helixtrans-58.4-45.6179.2171.30000111.5P524 M527 F528 L531 V544 A545 F551 F552 I599P524-V548 HydrophobicContact CB-CG1 4.4Å; P524-V548 WeakPolarHBondContact O-CG1 3.46Å; M527-V548 HydrophobicContact CG-CG2 4.23Å; M527-V548 HydrophobicContact SD-CG2 4.38Å; F528-V548 HydrophobicContact CB-CG1 4.42Å; F528-V548 HydrophobicContact CB-CG2 4.36Å; L531-V548 HydrophobicContact CD1-CG2 3.68Å; V544-V548 HydrophobicContact CG1-CG2 4.33Å; V544-V548 WeakPolarHBondContact O-CG2 3.46Å; V544-V548 PolarHBondContact O-N 3.06Å; A545-V548 PolarHBondContact O-N 2.72Å; V548-F551 PolarHBondContact O-N 3.08Å; V548-F552 HydrophobicContact CG1-CD2 3.95Å; V548-F552 HydrophobicContact CG1-CE2 4.19Å; V548-F552 WeakPolarHBondContact O-CD2 3.47Å; V548-F552 PolarHBondContact O-N 3.11Å; V548-I599 HydrophobicContact CG1-CD1 4.1Å
549K98.3Very high97.4Very high44 Ų4442.8 Ų42.819%0.19121%0.21CC..Hα-helixtrans-62.7-45.3177.9-72.4177.9172.5-170.10111.8A545 Q546 K547 R553 F596 D600A545-K549 VanDerWaalsContact O-CB 3.32Å; A545-K549 WeakPolarHBondContact O-CB 3.29Å; A545-K549 WeakPolarHBondContact O-CG 3.39Å; A545-K549 PolarHBondContact O-N 3.37Å; Q546-K549 PolarHBondContact O-N 3.07Å; K547-K549 VanDerWaalsContact C-N 3.33Å; K547-K549 PolarHBondContact O-N 3.09Å; K549-R553 VanDerWaalsContact O-CB 3.32Å; K549-R553 WeakPolarHBondContact O-CB 3.38Å; K549-R553 PolarHBondContact O-N 3.49Å; K549-F596 HydrophobicContact CB-CD2 4.32Å; K549-F596 HydrophobicContact CB-CE1 4.16Å; K549-F596 HydrophobicContact CB-CE2 3.93Å; K549-F596 HydrophobicContact CB-CZ 3.84Å; K549-F596 HydrophobicContact CD-CB 4.47Å; K549-F596 HydrophobicContact CD-CD2 4.22Å; K549-F596 HydrophobicContact CD-CG 4.18Å; K549-F596 HydrophobicContact CG-CD1 3.76Å; K549-F596 HydrophobicContact CG-CD2 3.94Å; K549-F596 HydrophobicContact CG-CE1 3.83Å; K549-F596 HydrophobicContact CG-CE2 4.01Å; K549-F596 HydrophobicContact CG-CG 3.82Å; K549-F596 HydrophobicContact CG-CZ 3.96Å; K549-F596 WeakPolarHBondContact O-CZ 3.18Å; K549-D600 IonicContact NZ-OD1 2.87Å; K549-D600 PolarHBondContact NZ-OD1 3.24Å; K549-D600 IonicContact NZ-OD2 3.56Å; K549-D600 PolarHBondContact NZ-OD2 3.25Å
550H97.6Very high97.6Very high67 Ų6744.9 Ų44.931%0.3122%0.219SC..Hα-helixtrans-58-50.1176-17857.6000111.3M503 M505 Q546 K547 F552 R553 M554M503-H550 PolarHBondContact O-NE2 3.38Å; M505-H550 HydrophobicContact CE-CB 4.07Å; Q546-H550 VanDerWaalsContact O-CB 3.29Å; Q546-H550 WeakPolarHBondContact O-CB 3.43Å; Q546-H550 PolarHBondContact O-N 3.34Å; K547-H550 PolarHBondContact O-N 3.02Å; H550-F552 PolarHBondContact O-N 2.9Å; H550-R553 PolarHBondContact O-N 3.31Å; H550-M554 WeakPolarHBondContact O-CG 3.19Å; H550-M554 PolarHBondContact O-N 3.2Å
551F98Very high97.7Very high3 Ų344.1 Ų44.11%0.01321%0.21CC..Hα-helixtrans-56.1-55178.7170.5-103.9000111.7L434 M505 L510 I513 M527 K547 V548 R553 M554 Y555L434-F551 HydrophobicContact CD1-CZ 4.28Å; L434-F551 HydrophobicContact CD2-CE2 4.07Å; L434-F551 HydrophobicContact CD2-CZ 4.13Å; L434-F551 HydrophobicContact CG-CE2 4.08Å; L434-F551 HydrophobicContact CG-CZ 4.15Å; M505-F551 HydrophobicContact CE-CB 3.49Å; M505-F551 VanDerWaalsContact CE-CB 3.49Å; M505-F551 HydrophobicContact SD-CB 4.06Å; M505-F551 HydrophobicContact SD-CD2 4.42Å; L510-F551 HydrophobicContact CD2-CD2 4.29Å; I513-F551 HydrophobicContact CD1-CB 4.44Å; I513-F551 HydrophobicContact CD1-CG 4.46Å; I513-F551 HydrophobicContact CG2-CD1 3.52Å; I513-F551 HydrophobicContact CG2-CD2 3.62Å; I513-F551 HydrophobicContact CG2-CE1 3.39Å; I513-F551 HydrophobicContact CG2-CE2 3.48Å; I513-F551 VanDerWaalsContact CG2-CE2 3.48Å; I513-F551 HydrophobicContact CG2-CG 3.64Å; I513-F551 HydrophobicContact CG2-CZ 3.37Å; M527-F551 HydrophobicContact CE-CE1 4.27Å; M527-F551 HydrophobicContact SD-CD1 4.39Å; K547-F551 PolarHBondContact O-N 3.31Å; V548-F551 PolarHBondContact O-N 3.08Å; F551-R553 VanDerWaalsContact C-N 3.3Å; F551-R553 PolarHBondContact O-N 3.46Å; F551-M554 PolarHBondContact O-N 2.98Å; F551-Y555 WeakPolarHBondContact O-CB 3.28Å; F551-Y555 PolarHBondContact O-N 3.17Å
552F98.4Very high97.8Very high7 Ų742.4 Ų42.43%0.03120%0.198CC..Hα-helixtrans-66.1-33.4-175.9-87.1-82.1000112.5P524 M527 V548 H550 S556 W592 F596P524-F552 VanDerWaalsContact CA-CE2 3.45Å; P524-F552 HydrophobicContact CB-CD2 3.87Å; P524-F552 HydrophobicContact CB-CE2 4.05Å; P524-F552 HydrophobicContact CB-CG 4.19Å; P524-F552 HydrophobicContact CG-CB 4.4Å; P524-F552 HydrophobicContact CG-CD1 3.79Å; P524-F552 HydrophobicContact CG-CD2 3.9Å; P524-F552 HydrophobicContact CG-CE1 3.96Å; P524-F552 HydrophobicContact CG-CE2 4.08Å; P524-F552 HydrophobicContact CG-CG 3.76Å; P524-F552 HydrophobicContact CG-CZ 4.11Å; M527-F552 HydrophobicContact CB-CE2 4.33Å; M527-F552 HydrophobicContact CE-CE2 3.65Å; M527-F552 HydrophobicContact CE-CZ 3.77Å; M527-F552 HydrophobicContact SD-CE2 3.64Å; M527-F552 HydrophobicContact SD-CZ 4.37Å; V548-F552 HydrophobicContact CG1-CD2 3.95Å; V548-F552 HydrophobicContact CG1-CE2 4.19Å; V548-F552 WeakPolarHBondContact O-CD2 3.47Å; V548-F552 PolarHBondContact O-N 3.11Å; H550-F552 PolarHBondContact O-N 2.9Å; F552-S556 WeakPolarHBondContact O-CB 3.46Å; F552-S556 PolarHBondContact O-N 3.05Å; F552-S556 PolarHBondContact O-OG 2.73Å; F552-W592 HydrophobicContact CD1-CH2 4.24Å; F552-W592 HydrophobicContact CD1-CZ2 4.04Å; F552-W592 PolarHBondContact O-NE1 3.31Å; F552-W592 VanDerWaalsContact O-NE1 3.17Å; F552-F596 HydrophobicContact CB-CE1 4.22Å; F552-F596 HydrophobicContact CB-CZ 4.18Å
553R97.7Very high97.8Very high142 Ų14240.1 Ų40.154%0.53619%0.189SC..Hα-helixtrans-61.3-56.3171.9-176.1176.3-179.4172.40.4110.2K549 H550 F551 Y555 S556 V557K549-R553 VanDerWaalsContact O-CB 3.32Å; K549-R553 WeakPolarHBondContact O-CB 3.38Å; K549-R553 PolarHBondContact O-N 3.49Å; H550-R553 PolarHBondContact O-N 3.31Å; F551-R553 VanDerWaalsContact C-N 3.3Å; F551-R553 PolarHBondContact O-N 3.46Å; R553-Y555 PolarHBondContact O-N 2.83Å; R553-S556 PolarHBondContact O-N 3.27Å; R553-S556 PolarHBondContact O-OG 3.49Å; R553-V557 HydrophobicContact CG-CG2 4.49Å; R553-V557 VanDerWaalsContact O-CG2 3.31Å; R553-V557 WeakPolarHBondContact O-CG2 3.48Å; R553-V557 PolarHBondContact O-N 3.32Å
554M97.1Very high97.8Very high73 Ų7338.7 Ų38.736%0.3619%0.186SC..Hα-helixtrans-62.5-45.9-177.9-65.8-51.9-68.100112.6H550 F551 S556 V557 N558H550-M554 WeakPolarHBondContact O-CG 3.19Å; H550-M554 PolarHBondContact O-N 3.2Å; F551-M554 PolarHBondContact O-N 2.98Å; M554-S556 VanDerWaalsContact C-N 3.31Å; M554-S556 PolarHBondContact O-N 2.87Å; M554-V557 PolarHBondContact O-N 3.04Å; M554-N558 WeakPolarHBondContact O-CB 3.32Å; M554-N558 PolarHBondContact O-N 2.86Å; M554-N558 PolarHBondContact O-ND2 3.09Å
555Y98Very high97.7Very high4 Ų439.3 Ų39.32%0.01619%0.19CC..Hα-helixtrans-52.2-49172.6164.1-93.1000111.3L434 R517 F551 R553 N558 R559 Y588L434-Y555 HydrophobicContact CD1-CD2 4.15Å; L434-Y555 HydrophobicContact CD1-CE2 4.32Å; L434-Y555 WeakPolarHBondContact O-CD2 3.41Å; R517-Y555 VanDerWaalsContact NH2-CZ 3.32Å; R517-Y555 PolarHBondContact NH2-OH 3.01Å; F551-Y555 WeakPolarHBondContact O-CB 3.28Å; F551-Y555 PolarHBondContact O-N 3.17Å; R553-Y555 PolarHBondContact O-N 2.83Å; Y555-N558 PolarHBondContact O-N 2.81Å; Y555-R559 WeakPolarHBondContact O-CB 3.42Å; Y555-R559 PolarHBondContact O-N 3.06Å; Y555-Y588 HydrophobicContact CE1-CE2 4.05Å; Y555-Y588 PolarHBondContact OH-OH 3.44Å
556S98.3Very high97.7Very high2 Ų239.4 Ų39.41%0.01419%0.19CC..Hα-helixtrans-72.3-36.6-175.365.80000113.5F552 R553 M554 T590 W592F552-S556 WeakPolarHBondContact O-CB 3.46Å; F552-S556 PolarHBondContact O-N 3.05Å; F552-S556 PolarHBondContact O-OG 2.73Å; R553-S556 PolarHBondContact O-N 3.27Å; R553-S556 PolarHBondContact O-OG 3.49Å; M554-S556 VanDerWaalsContact C-N 3.31Å; M554-S556 PolarHBondContact O-N 2.87Å; S556-T590 WeakPolarHBondContact OG-CA 3.38Å; S556-W592 PolarHBondContact OG-NE1 2.84Å; S556-W592 VanDerWaalsContact OG-NE1 3.12Å
557V97.9Very high97.7Very high64 Ų6436 Ų3639%0.38818%0.178SC..Hα-helixtrans-64.2-43.5174.7169.70000110.5R553 M554 H560 T590R553-V557 HydrophobicContact CG-CG2 4.49Å; R553-V557 VanDerWaalsContact O-CG2 3.31Å; R553-V557 WeakPolarHBondContact O-CG2 3.48Å; R553-V557 PolarHBondContact O-N 3.32Å; M554-V557 PolarHBondContact O-N 3.04Å; V557-H560 PolarHBondContact O-CE1 2.98Å; V557-H560 PolarHBondContact O-ND1 2.92Å; V557-T590 HydrophobicContact CB-CG2 4.47Å; V557-T590 HydrophobicContact CG2-CG2 3.68Å
558N98.1Very high97.7Very high21 Ų2134.3 Ų34.311%0.11217%0.173CC..Hα-helixtrans-90.9-6.5-173.1-66.8-38.9000114.5T435 M554 Y555 H560 K561T435-N558 WeakPolarHBondContact O-CB 3.28Å; T435-N558 PolarHBondContact O-ND2 2.99Å; M554-N558 WeakPolarHBondContact O-CB 3.32Å; M554-N558 PolarHBondContact O-N 2.86Å; M554-N558 PolarHBondContact O-ND2 3.09Å; Y555-N558 PolarHBondContact O-N 2.81Å; N558-H560 PolarHBondContact O-N 3.01Å; N558-K561 HydrophobicContact CB-CD 4.4Å; N558-K561 WeakPolarHBondContact O-CB 3.42Å; N558-K561 WeakPolarHBondContact O-CG 3.35Å; N558-K561 PolarHBondContact O-N 2.89Å
559R98.1Very high97.8Very high3 Ų334.4 Ų34.41%0.01117%0.173CC..Hα-helixtrans-55.8-31.5-174.2-175.559.8179.9-179.83.7113.6Y555 K561 M562 P576 D578 D582 P585 F586 Y588Y555-R559 WeakPolarHBondContact O-CB 3.42Å; Y555-R559 PolarHBondContact O-N 3.06Å; R559-K561 PolarHBondContact O-N 3.2Å; R559-K561 VanDerWaalsContact O-N 3.1Å; R559-M562 WeakPolarHBondContact O-CB 3.48Å; R559-M562 PolarHBondContact O-N 2.79Å; R559-P576 VanDerWaalsContact CZ-O 3.32Å; R559-P576 PolarHBondContact NH1-O 2.82Å; R559-P576 PolarHBondContact NH2-O 3.26Å; R559-D578 IonicContact CZ-OD1 3.07Å; R559-D578 IonicContact NE-OD1 3.99Å; R559-D578 IonicContact NH2-OD1 3.87Å; R559-D578 PolarHBondContact NH2-OD1 2.83Å; R559-D582 PolarHBondContact NH2-O 3.31Å; R559-D582 IonicContact NH2-OD2 2.86Å; R559-P585 WeakPolarHBondContact CG-O 3.09Å; R559-F586 HydrophobicContact CG-CB 4.27Å; R559-Y588 HydrophobicContact CB-CD2 4.38Å; R559-Y588 HydrophobicContact CB-CE2 4.07Å; R559-Y588 HydrophobicContact CG-CE2 4Å
560H98.3Very high97.8Very high71 Ų7132.5 Ų32.533%0.32917%0.165SC..Hα-helixtrans-56.2-25.3175.373.5-86.3000113.8V557 N558 M562 T563V557-H560 PolarHBondContact O-CE1 2.98Å; V557-H560 PolarHBondContact O-ND1 2.92Å; N558-H560 PolarHBondContact O-N 3.01Å; H560-M562 VanDerWaalsContact C-N 3.31Å; H560-T563 PolarHBondContact O-N 3.45Å; H560-T563 PolarHBondContact O-OG1 3Å
561K98.1Very high97.8Very high31 Ų3129.4 Ų29.414%0.13515%0.151CC..Hα-helixtrans-67.5-32.6175.2-58.6-177.3-172.4175.40112G436 F438 K440 N558 R559 T563 T564 V565G436-K561 WeakPolarHBondContact O-CD 3.43Å; G436-K561 PolarHBondContact O-NZ 3.24Å; F438-K561 HydrophobicContact CD2-CD 4.39Å; F438-K561 HydrophobicContact CE1-CB 4.31Å; F438-K561 HydrophobicContact CE2-CB 3.78Å; F438-K561 HydrophobicContact CE2-CD 4.15Å; F438-K561 HydrophobicContact CE2-CG 4.48Å; F438-K561 HydrophobicContact CZ-CB 3.5Å; F438-K561 HydrophobicContact CZ-CD 4.24Å; F438-K561 HydrophobicContact CZ-CG 4.5Å; F438-K561 WeakPolarHBondContact O-CE 3.43Å; F438-K561 PolarHBondContact O-NZ 3.36Å; K440-K561 HydrophobicContact CB-CG 4.35Å; K440-K561 HydrophobicContact CD-CG 4.49Å; K440-K561 HydrophobicContact CG-CG 4.41Å; N558-K561 HydrophobicContact CB-CD 4.4Å; N558-K561 WeakPolarHBondContact O-CB 3.42Å; N558-K561 WeakPolarHBondContact O-CG 3.35Å; N558-K561 PolarHBondContact O-N 2.89Å; R559-K561 PolarHBondContact O-N 3.2Å; R559-K561 VanDerWaalsContact O-N 3.1Å; K561-T563 PolarHBondContact O-N 2.85Å; K561-T564 PolarHBondContact O-N 2.96Å; K561-T564 PolarHBondContact O-OG1 2.8Å; K561-V565 PolarHBondContact O-N 3.47Å
562M97.8Very high97.7Very high6 Ų629.8 Ų29.83%0.0315%0.152CC..Hα-helixtrans-68.4-20.3-179.9-69.5-54.3-59.400114.2F438 R559 H560 T564 V565 P576 D578F438-M562 HydrophobicContact CE1-SD 4.38Å; F438-M562 HydrophobicContact CZ-SD 4.43Å; R559-M562 WeakPolarHBondContact O-CB 3.48Å; R559-M562 PolarHBondContact O-N 2.79Å; H560-M562 VanDerWaalsContact C-N 3.31Å; M562-T564 PolarHBondContact O-N 3.04Å; M562-V565 HydrophobicContact CE-CB 4.16Å; M562-V565 HydrophobicContact CE-CG1 3.58Å; M562-V565 HydrophobicContact CE-CG2 4.41Å; M562-V565 WeakPolarHBondContact O-CG1 3.2Å; M562-V565 HydrophobicContact SD-CB 4.21Å; M562-V565 HydrophobicContact SD-CG1 4.28Å; M562-V565 HydrophobicContact SD-CG2 4.34Å; M562-P576 HydrophobicContact CE-CB 4.09Å; M562-P576 HydrophobicContact CE-CG 3.88Å; M562-P576 WeakPolarHBondContact CE-O 3.45Å; M562-D578 HydrophobicContact CB-CB 4.47Å
563T97.6Very high97.5Very high49 Ų4930.9 Ų30.930%0.30116%0.161SC..THydrogen-bonded Turntrans-68.5-21.5176.465.70000112.8H560 K561 F586H560-T563 PolarHBondContact O-N 3.45Å; H560-T563 PolarHBondContact O-OG1 3Å; K561-T563 PolarHBondContact O-N 2.85Å; T563-F586 HydrophobicContact CG2-CB 3.77Å; T563-F586 HydrophobicContact CG2-CD1 3.95Å; T563-F586 HydrophobicContact CG2-CG 3.85Å
564T96.5Very high97.5Very high52 Ų5224.1 Ų24.132%0.31914%0.136SC..THydrogen-bonded Turntrans-126.620-178.161.10000111.9K440 Y441 K561 M562K440-T564 WeakPolarHBondContact CE-OG1 2.95Å; Y441-T564 HydrophobicContact CE1-CG2 4.48Å; K561-T564 PolarHBondContact O-N 2.96Å; K561-T564 PolarHBondContact O-OG1 2.8Å; M562-T564 PolarHBondContact O-N 3.04Å
565V94.4Very high97.5Very high14 Ų1420.8 Ų20.89%0.08512%0.119CC..PPolyproline II helixtrans-70.7148.6175.476.30000109.7F438 K561 M562F438-V565 HydrophobicContact CZ-CG2 4.31Å; K561-V565 PolarHBondContact O-N 3.47Å; M562-V565 HydrophobicContact CE-CB 4.16Å; M562-V565 HydrophobicContact CE-CG1 3.58Å; M562-V565 HydrophobicContact CE-CG2 4.41Å; M562-V565 WeakPolarHBondContact O-CG1 3.2Å; M562-V565 HydrophobicContact SD-CB 4.21Å; M562-V565 HydrophobicContact SD-CG1 4.28Å; M562-V565 HydrophobicContact SD-CG2 4.34Å
566T98.2Very high97.5Very high6 Ų620.7 Ų20.74%0.03712%0.119CC..PPolyproline II helixtrans-54.3136.2173.7-560000111.6S444 S445 A446 I448 N449 S568S444-T566 PolarHBondContact O-OG1 3.05Å; S445-T566 VanDerWaalsContact CA-OG1 3.3Å; S445-T566 WeakPolarHBondContact CA-OG1 3.25Å; A446-T566 HydrophobicContact CB-CG2 4.18Å; A446-T566 PolarHBondContact N-OG1 3.48Å; A446-T566 VanDerWaalsContact O-CG2 3.3Å; A446-T566 WeakPolarHBondContact O-CG2 3.49Å; A446-T566 PolarHBondContact O-OG1 3.48Å; I448-T566 VanDerWaalsContact C-CG2 3.47Å; N449-T566 HydrophobicContact CB-CG2 3.89Å; T566-S568 PolarHBondContact O-N 3.46Å
567P98.2Very high97.5Very high51 Ų5120.7 Ų20.733%0.33112%0.119SC..PPolyproline II helixtrans-56.2124.5169.4-22.833.5000111.2N449N449-P567 PolarHBondContact N-O 3.46Å
568S97.6Very high97.4Very high11 Ų1119 Ų198%0.07711%0.108CC..BIsolated β-bridgetrans-119.1144.7-175.356.60000113.2R152 N449 T566 H570R152-S568 WeakPolarHBondContact CB-O 3.05Å; N449-S568 CarbonylContact O-C 3.56Å; N449-S568 WeakPolarHBondContact O-CA 3.4Å; N449-S568 WeakPolarHBondContact O-CB 3.4Å; T566-S568 PolarHBondContact O-N 3.46Å; S568-H570 PolarHBondContact O-N 3.49Å
569Y98.7Very high97.4Very high1 Ų121 Ų210%0.00412%0.118CC..  trans-47.7129170.2-179.9-88.4000110.1H117 Y154 P248 W251 N449 P450 G453 A571H117-Y569 VanDerWaalsContact CG-OH 3.29Å; H117-Y569 AromaticContact ND1-CE1 3.53Å; H117-Y569 AromaticContact ND1-CZ 3.49Å; H117-Y569 PolarHBondContact ND1-OH 3.15Å; Y154-Y569 HydrophobicContact CG-CE2 4.1Å; P248-Y569 HydrophobicContact CB-CD2 4.42Å; P248-Y569 HydrophobicContact CB-CG 4.47Å; P248-Y569 HydrophobicContact CG-CD1 3.95Å; P248-Y569 HydrophobicContact CG-CD2 4.39Å; P248-Y569 HydrophobicContact CG-CE1 3.89Å; P248-Y569 HydrophobicContact CG-CE2 4.29Å; P248-Y569 HydrophobicContact CG-CG 4.22Å; W251-Y569 HydrophobicContact CB-CD2 3.66Å; W251-Y569 HydrophobicContact CB-CE2 3.71Å; W251-Y569 AromaticContact CD1-CD2 3.98Å; W251-Y569 AromaticContact CD2-CD2 3.7Å; W251-Y569 HydrophobicContact CD2-CD2 3.7Å; W251-Y569 HydrophobicContact CE3-CD2 4.08Å; W251-Y569 AromaticContact CG-CD2 3.52Å; W251-Y569 HydrophobicContact CG-CD2 3.52Å; W251-Y569 AromaticContact CG-CE2 3.99Å; W251-Y569 HydrophobicContact CG-CE2 3.99Å; N449-Y569 PolarHBondContact O-N 3.04Å; P450-Y569 WeakPolarHBondContact O-CB 3.48Å; G453-Y569 WeakPolarHBondContact CA-O 3.43Å; G453-Y569 PolarHBondContact N-O 3.06Å; Y569-A571 HydrophobicContact CD1-CB 3.9Å; Y569-A571 HydrophobicContact CE1-CB 3.85Å; Y569-A571 PolarHBondContact O-N 2.83Å
570H98.6Very high97.3Very high5 Ų526.8 Ų26.82%0.02314%0.14CC..  trans-81.7117.3176.7-170.385.7000110.7H116 R152 L153 S568 F581H116-H570 AromaticContact CD2-CD2 3.49Å; H116-H570 PolarHBondContact CD2-CD2 3.49Å; H116-H570 VanDerWaalsContact CD2-CD2 3.49Å; H116-H570 AromaticContact NE2-CD2 3.63Å; H116-H570 AromaticContact NE2-NE2 3.7Å; R152-H570 PolarHBondContact O-N 3.43Å; L153-H570 HydrophobicContact CD2-CB 3.61Å; S568-H570 PolarHBondContact O-N 3.49Å; H570-F581 AromaticContact CE1-CD2 3.51Å; H570-F581 AromaticContact CE1-CE2 3.52Å; H570-F581 AromaticContact CE1-CG 3.78Å; H570-F581 AromaticContact CE1-CZ 3.79Å; H570-F581 AromaticContact NE2-CE2 3.96Å
571A97.9Very high97.2Very high2 Ų224.5 Ų24.52%0.01713%0.13CC..  trans-127.9-63.2175.700000111.2E118 L119 G453 I454 Y569E118-A571 CarbonylContact C-O 3.52Å; E118-A571 WeakPolarHBondContact CA-O 3.47Å; E118-A571 WeakPolarHBondContact CG-O 3.16Å; L119-A571 HydrophobicContact CB-CB 4.24Å; L119-A571 PolarHBondContact N-O 3.34Å; G453-A571 WeakPolarHBondContact O-CB 3.49Å; I454-A571 HydrophobicContact CG1-CB 3.91Å; Y569-A571 HydrophobicContact CD1-CB 3.9Å; Y569-A571 HydrophobicContact CE1-CB 3.85Å; Y569-A571 PolarHBondContact O-N 2.83Å
572E96.9Very high97.2Very high10 Ų1023.2 Ų23.25%0.04712%0.124CC..  trans-79.7136.1-176.1-68.8-83.5-14500113.1R120 G453 Y574 S575R120-E572 IonicContact NH1-OE1 3.02Å; G453-E572 WeakPolarHBondContact O-CB 3.49Å; G453-E572 WeakPolarHBondContact O-CG 3.48Å; G453-E572 PolarHBondContact O-N 3.35Å; E572-Y574 HydrophobicContact CB-CD1 3.86Å; E572-Y574 HydrophobicContact CB-CE1 3.64Å; E572-Y574 HydrophobicContact CG-CD1 4.47Å; E572-Y574 HydrophobicContact CG-CE1 3.76Å; E572-Y574 PolarHBondContact O-N 3.39Å; E572-Y574 PolarHBondContact OE1-OH 3.28Å; E572-Y574 WeakPolarHBondContact OE2-CE1 3.29Å; E572-S575 PolarHBondContact O-N 3.46Å; E572-S575 VanDerWaalsContact O-N 3.16Å
573S94.5Very high97.2Very high30 Ų3027.8 Ų27.821%0.2115%0.148CC..THydrogen-bonded Turntrans-70.3-0.8178.363.40000114.7E118 I519 F581E118-S573 VanDerWaalsContact OE1-CB 3.23Å; E118-S573 WeakPolarHBondContact OE1-CB 3.41Å; I519-S573 WeakPolarHBondContact CD1-OG 3.49Å; S573-F581 VanDerWaalsContact O-CE1 3.3Å; S573-F581 WeakPolarHBondContact O-CE1 3.19Å; S573-F581 VanDerWaalsContact O-CZ 3.28Å; S573-F581 WeakPolarHBondContact O-CZ 3.17Å
574Y97.4Very high97.2Very high1 Ų129.9 Ų29.90%0.00415%0.15CC..THydrogen-bonded Turntrans-111.516.7174.467.8-85.9000114.6V430 S455 R515 E572V430-Y574 HydrophobicContact CG1-CE2 3.8Å; V430-Y574 HydrophobicContact CG2-CE2 4.32Å; S455-Y574 WeakPolarHBondContact CB-OH 3.41Å; R515-Y574 HydrophobicContact CG-CD1 3.66Å; R515-Y574 HydrophobicContact CG-CE1 4.09Å; R515-Y574 HydrophobicContact CG-CG 4.11Å; E572-Y574 HydrophobicContact CB-CD1 3.86Å; E572-Y574 HydrophobicContact CB-CE1 3.64Å; E572-Y574 HydrophobicContact CG-CD1 4.47Å; E572-Y574 HydrophobicContact CG-CE1 3.76Å; E572-Y574 PolarHBondContact O-N 3.39Å; E572-Y574 PolarHBondContact OE1-OH 3.28Å; E572-Y574 WeakPolarHBondContact OE2-CE1 3.29Å
575S97.1Very high97.3Very high3 Ų331 Ų312%0.02116%0.159CC..  trans-48.3135.6178.4178.30000113.1E572 D577 F581E572-S575 PolarHBondContact O-N 3.46Å; E572-S575 VanDerWaalsContact O-N 3.16Å; S575-D577 VanDerWaalsContact C-N 3.3Å; S575-D577 PolarHBondContact OG-N 3.48Å; S575-F581 WeakPolarHBondContact O-CD1 3.32Å
576P97.6Very high97.5Very high1 Ų136 Ų361%0.00618%0.18CC..  trans-85.57.4174.934.7-35.1000113.5V430 L434 R559 M562 D578V430-P576 VanDerWaalsContact CG2-CD 3.48Å; V430-P576 HydrophobicContact CG2-CG 4.48Å; L434-P576 HydrophobicContact CB-CB 4.34Å; L434-P576 HydrophobicContact CB-CG 4.14Å; L434-P576 HydrophobicContact CD1-CB 4.03Å; R559-P576 VanDerWaalsContact CZ-O 3.32Å; R559-P576 PolarHBondContact NH1-O 2.82Å; R559-P576 PolarHBondContact NH2-O 3.26Å; M562-P576 HydrophobicContact CE-CB 4.09Å; M562-P576 HydrophobicContact CE-CG 3.88Å; M562-P576 WeakPolarHBondContact CE-O 3.45Å; P576-D578 PolarHBondContact O-N 3.36Å
577D97.4Very high97.5Very high3 Ų343 Ų432%0.01622%0.216CC..  trans-51.8124.3-178.4168.6-113.3000112.7R152 S575 N579 R580 F581 D582R152-D577 VanDerWaalsContact CZ-CG 3.43Å; R152-D577 IonicContact CZ-OD1 2.71Å; R152-D577 IonicContact CZ-OD2 2.74Å; R152-D577 IonicContact NH1-OD1 3.58Å; R152-D577 PolarHBondContact NH1-OD1 3.44Å; R152-D577 IonicContact NH1-OD2 3.59Å; R152-D577 PolarHBondContact NH1-OD2 2.84Å; R152-D577 IonicContact NH2-OD2 2.93Å; R152-D577 PolarHBondContact NH2-OD2 3.46Å; R152-D577 VanDerWaalsContact NH2-OD2 3.09Å; S575-D577 VanDerWaalsContact C-N 3.3Å; S575-D577 PolarHBondContact OG-N 3.48Å; D577-N579 PolarHBondContact OD1-N 3.35Å; D577-N579 PolarHBondContact OD2-N 3.09Å; D577-N579 PolarHBondContact OD2-ND2 2.91Å; D577-R580 PolarHBondContact OD1-N 3.39Å; D577-F581 HydrophobicContact CB-CB 4.42Å; D577-F581 PolarHBondContact OD1-N 3.34Å; D577-D582 CarbonylContact O-C 3.56Å; D577-D582 WeakPolarHBondContact O-CA 3.42Å; D577-D582 WeakPolarHBondContact O-CB 3.47Å; D577-D582 PolarHBondContact O-N 2.76Å
578D97.3Very high97.5Very high28 Ų2842.8 Ų42.815%0.1521%0.209CC..THydrogen-bonded Turntrans-85.9-19-177.5-157.763.1000113.2R559 M562 P576 L583 R584R559-D578 IonicContact CZ-OD1 3.07Å; R559-D578 IonicContact NE-OD1 3.99Å; R559-D578 IonicContact NH2-OD1 3.87Å; R559-D578 PolarHBondContact NH2-OD1 2.83Å; M562-D578 HydrophobicContact CB-CB 4.47Å; P576-D578 PolarHBondContact O-N 3.36Å; D578-L583 VanDerWaalsContact O-CD2 3.28Å; D578-L583 WeakPolarHBondContact O-CD2 3.5Å; D578-R584 PolarHBondContact OD1-N 2.56Å
579N96.4Very high97.5Very high63 Ų6346.8 Ų46.834%0.33723%0.229SC..THydrogen-bonded Turntrans-72.7-37.4-173.1-68.8-82.8000112.8R152 D577R152-N579 PolarHBondContact NH2-ND2 3.28Å; D577-N579 PolarHBondContact OD1-N 3.35Å; D577-N579 PolarHBondContact OD2-N 3.09Å; D577-N579 PolarHBondContact OD2-ND2 2.91Å
580R95.9Very high97.4Very high125 Ų12548.5 Ų48.547%0.47224%0.24SC..THydrogen-bonded Turntrans-136.3-48.6-172.9-64.2-64.7-179.5-89.6-2.1112.8T35 R37 D577T35-R580 HydrophobicContact CG2-CB 4.13Å; R37-R580 PolarHBondContact NH2-O 2.96Å; D577-R580 PolarHBondContact OD1-N 3.39Å
581F97.7Very high97.3Very high23 Ų2353.5 Ų53.510%0.10126%0.263CS..THydrogen-bonded Turntrans-89.4-36.8-163.2-171.6-108.6000114.2T35 K518 H570 S573 S575 D577T35-F581 WeakPolarHBondContact OG1-CD2 3.46Å; K518-F581 HydrophobicContact CD-CE1 4.41Å; K518-F581 HydrophobicContact CG-CE1 4.18Å; K518-F581 PolarHBondContact NZ-O 3.49Å; H570-F581 AromaticContact CE1-CD2 3.51Å; H570-F581 AromaticContact CE1-CE2 3.52Å; H570-F581 AromaticContact CE1-CG 3.78Å; H570-F581 AromaticContact CE1-CZ 3.79Å; H570-F581 AromaticContact NE2-CE2 3.96Å; S573-F581 VanDerWaalsContact O-CE1 3.3Å; S573-F581 WeakPolarHBondContact O-CE1 3.19Å; S573-F581 VanDerWaalsContact O-CZ 3.28Å; S573-F581 WeakPolarHBondContact O-CZ 3.17Å; S575-F581 WeakPolarHBondContact O-CD1 3.32Å; D577-F581 HydrophobicContact CB-CB 4.42Å; D577-F581 PolarHBondContact OD1-N 3.34Å
582D97.9Very high97.3Very high3 Ų354.9 Ų54.92%0.01627%0.268CS..  trans-132.469.8-172.2-167.637.1000112.8R517 K518 R559 D577 R584R517-D582 IonicContact CZ-OD2 2.83Å; R517-D582 IonicContact NH1-OD1 3.92Å; R517-D582 IonicContact NH1-OD2 3.43Å; R517-D582 PolarHBondContact NH1-OD2 2.85Å; R517-D582 IonicContact NH2-OD1 2.74Å; R517-D582 IonicContact NH2-OD2 2.72Å; R517-D582 PolarHBondContact NH2-OD2 2.8Å; K518-D582 HydrophobicContact CD-CB 4.44Å; K518-D582 WeakPolarHBondContact CD-OD1 3.36Å; K518-D582 VanDerWaalsContact NZ-CA 3.34Å; K518-D582 IonicContact NZ-OD1 3.83Å; K518-D582 PolarHBondContact NZ-OD1 3.27Å; R559-D582 PolarHBondContact NH2-O 3.31Å; R559-D582 IonicContact NH2-OD2 2.86Å; D577-D582 CarbonylContact O-C 3.56Å; D577-D582 WeakPolarHBondContact O-CA 3.42Å; D577-D582 WeakPolarHBondContact O-CB 3.47Å; D577-D582 PolarHBondContact O-N 2.76Å; D582-R584 WeakPolarHBondContact O-CG 3.45Å; D582-R584 PolarHBondContact O-N 2.74Å; D582-R584 IonicContact OD1-CZ 3.45Å; D582-R584 IonicContact OD1-NE 3.19Å; D582-R584 PolarHBondContact OD1-NE 3.17Å; D582-R584 VanDerWaalsContact OD1-NE 3.07Å; D582-R584 IonicContact OD1-NH2 3.69Å; D582-R584 IonicContact OD2-NE 3.19Å
583L97.6Very high97.4Very high103 Ų10358.6 Ų58.654%0.53929%0.288SS..  trans-61119.7175.2-60.7-175.5000111.7R37 D578R37-L583 VanDerWaalsContact CZ-CD1 3.45Å; R37-L583 VanDerWaalsContact NH1-CD1 3.29Å; D578-L583 VanDerWaalsContact O-CD2 3.28Å; D578-L583 WeakPolarHBondContact O-CD2 3.5Å
584R98.1Very high97.6Very high92 Ų9266.3 Ų66.335%0.34731%0.313SS..  trans-144.8157-178.8-65.6-66-176.91536.3111D578 D582D578-R584 PolarHBondContact OD1-N 2.56Å; D582-R584 WeakPolarHBondContact O-CG 3.45Å; D582-R584 PolarHBondContact O-N 2.74Å; D582-R584 IonicContact OD1-CZ 3.45Å; D582-R584 IonicContact OD1-NE 3.19Å; D582-R584 PolarHBondContact OD1-NE 3.17Å; D582-R584 VanDerWaalsContact OD1-NE 3.07Å; D582-R584 IonicContact OD1-NH2 3.69Å; D582-R584 IonicContact OD2-NE 3.19Å
585P98.4Very high97.7Very high76 Ų7669.4 Ų69.449%0.49433%0.327SS..  trans-55151.6162.1-22.932.4000110.8R559 Y588R559-P585 WeakPolarHBondContact CG-O 3.09Å; P585-Y588 HydrophobicContact CB-CD1 4.35Å; P585-Y588 HydrophobicContact CB-CE1 3.92Å; P585-Y588 HydrophobicContact CB-CE2 4.17Å; P585-Y588 WeakPolarHBondContact CD-OH 3.41Å; P585-Y588 HydrophobicContact CG-CE1 4Å; P585-Y588 WeakPolarHBondContact O-CE2 3.4Å; P585-Y588 VanDerWaalsContact O-CZ 3.29Å; P585-Y588 PolarHBondContact O-OH 3.32Å
586F97.9Very high97.7Very high120 Ų12070.4 Ų70.453%0.52633%0.331SS..SBendtrans-116.6-6.5170.259.9-95.5000112.7R559 T563R559-F586 HydrophobicContact CG-CB 4.27Å; T563-F586 HydrophobicContact CG2-CB 3.77Å; T563-F586 HydrophobicContact CG2-CD1 3.95Å; T563-F586 HydrophobicContact CG2-CG 3.85Å
587L98.3Very high97.8Very high153 Ų15375.6 Ų75.680%0.80136%0.355SS*.SBendtrans-113.1102.5168.6179.662.7000108.3
588Y98.4Very high97.8Very high45 Ų4577.2 Ų77.218%0.17637%0.367CS..  trans-109.2156.6180-74-83000111.4Y555 R559 P585 T590 W592Y555-Y588 HydrophobicContact CE1-CE2 4.05Å; Y555-Y588 PolarHBondContact OH-OH 3.44Å; R559-Y588 HydrophobicContact CB-CD2 4.38Å; R559-Y588 HydrophobicContact CB-CE2 4.07Å; R559-Y588 HydrophobicContact CG-CE2 4Å; P585-Y588 HydrophobicContact CB-CD1 4.35Å; P585-Y588 HydrophobicContact CB-CE1 3.92Å; P585-Y588 HydrophobicContact CB-CE2 4.17Å; P585-Y588 WeakPolarHBondContact CD-OH 3.41Å; P585-Y588 HydrophobicContact CG-CE1 4Å; P585-Y588 WeakPolarHBondContact O-CE2 3.4Å; P585-Y588 VanDerWaalsContact O-CZ 3.29Å; P585-Y588 PolarHBondContact O-OH 3.32Å; Y588-T590 PolarHBondContact O-N 3.35Å; Y588-W592 AromaticContact CD1-CH2 3.99Å; Y588-W592 HydrophobicContact CD1-CH2 3.99Å; Y588-W592 AromaticContact CD1-CZ2 3.94Å; Y588-W592 HydrophobicContact CD1-CZ2 3.94Å; Y588-W592 AromaticContact CE1-CH2 3.97Å; Y588-W592 HydrophobicContact CE1-CH2 3.97Å; Y588-W592 HydrophobicContact CE1-CZ2 4.2Å; Y588-W592 HydrophobicContact CG-CZ2 4.42Å
589N97.9Very high97.9Very high95 Ų9575.9 Ų75.951%0.50836%0.359SS..  trans-73.6101153-179.3-8.8000108.3H591 W592N589-H591 PolarHBondContact O-N 3.42Å; N589-H591 VanDerWaalsContact O-N 3.17Å; N589-H591 WeakPolarHBondContact OD1-CB 3.46Å; N589-H591 PolarHBondContact OD1-N 3.12Å; N589-H591 VanDerWaalsContact OD1-N 3.12Å; N589-H591 PolarHBondContact OD1-ND1 3.05Å; N589-W592 PolarHBondContact O-N 3.43Å
590T96.9Very high97.9Very high37 Ų3776.1 Ų76.123%0.22736%0.361CS..THydrogen-bonded Turntrans-71.6-6.9-173.359.20000114.2S556 V557 Y588S556-T590 WeakPolarHBondContact OG-CA 3.38Å; V557-T590 HydrophobicContact CB-CG2 4.47Å; V557-T590 HydrophobicContact CG2-CG2 3.68Å; Y588-T590 PolarHBondContact O-N 3.35Å
591H96.7Very high98Very high110 Ų11074.7 Ų74.751%0.50936%0.362SS..THydrogen-bonded Turntrans-85.5-17.9175.8-60.188.4000112.7N589 N593 F596N589-H591 PolarHBondContact O-N 3.42Å; N589-H591 VanDerWaalsContact O-N 3.17Å; N589-H591 WeakPolarHBondContact OD1-CB 3.46Å; N589-H591 PolarHBondContact OD1-N 3.12Å; N589-H591 VanDerWaalsContact OD1-N 3.12Å; N589-H591 PolarHBondContact OD1-ND1 3.05Å; H591-N593 WeakPolarHBondContact CB-OD1 3.36Å; H591-N593 PolarHBondContact O-N 2.82Å; H591-F596 WeakPolarHBondContact O-CD2 3.41Å; H591-F596 WeakPolarHBondContact O-CE2 3.27Å
592W98.1Very high98Very high32 Ų3276.9 Ų76.912%0.12137%0.373CS..  trans47.839.4179-62.289.8000112.9P524 F552 S556 Y588 N589 W594 Q595 F596P524-W592 HydrophobicContact CG-CD2 4.27Å; P524-W592 HydrophobicContact CG-CE3 3.8Å; P524-W592 HydrophobicContact CG-CZ3 4.16Å; F552-W592 HydrophobicContact CD1-CH2 4.24Å; F552-W592 HydrophobicContact CD1-CZ2 4.04Å; F552-W592 PolarHBondContact O-NE1 3.31Å; F552-W592 VanDerWaalsContact O-NE1 3.17Å; S556-W592 PolarHBondContact OG-NE1 2.84Å; S556-W592 VanDerWaalsContact OG-NE1 3.12Å; Y588-W592 AromaticContact CD1-CH2 3.99Å; Y588-W592 HydrophobicContact CD1-CH2 3.99Å; Y588-W592 AromaticContact CD1-CZ2 3.94Å; Y588-W592 HydrophobicContact CD1-CZ2 3.94Å; Y588-W592 AromaticContact CE1-CH2 3.97Å; Y588-W592 HydrophobicContact CE1-CH2 3.97Å; Y588-W592 HydrophobicContact CE1-CZ2 4.2Å; Y588-W592 HydrophobicContact CG-CZ2 4.42Å; N589-W592 PolarHBondContact O-N 3.43Å; W592-W594 VanDerWaalsContact C-N 3.33Å; W592-W594 PolarHBondContact O-N 3.36Å; W592-W594 VanDerWaalsContact O-N 3.13Å; W592-Q595 HydrophobicContact CE3-CG 4.3Å; W592-Q595 PolarHBondContact O-N 3.11Å; W592-Q595 PolarHBondContact O-OE1 2.72Å; W592-F596 HydrophobicContact CB-CD1 3.7Å; W592-F596 HydrophobicContact CB-CD2 4.08Å; W592-F596 HydrophobicContact CB-CE1 3.56Å; W592-F596 HydrophobicContact CB-CE2 3.95Å; W592-F596 HydrophobicContact CB-CG 3.97Å; W592-F596 HydrophobicContact CB-CZ 3.69Å; W592-F596 AromaticContact CD1-CZ 3.83Å; W592-F596 HydrophobicContact CG-CE1 4.02Å; W592-F596 HydrophobicContact CG-CE2 4.5Å; W592-F596 AromaticContact CG-CZ 3.95Å; W592-F596 HydrophobicContact CG-CZ 3.95Å; W592-F596 PolarHBondContact O-N 2.93Å
593N97.9Very high97.8Very high87 Ų8778.4 Ų78.447%0.46538%0.381SS..Hα-helixtrans-45.1-53.8-164.9-68.9-24.6000113H591 Q597H591-N593 WeakPolarHBondContact CB-OD1 3.36Å; H591-N593 PolarHBondContact O-N 2.82Å; N593-Q597 WeakPolarHBondContact O-CB 3.39Å; N593-Q597 WeakPolarHBondContact O-CG 3.49Å; N593-Q597 PolarHBondContact O-N 3.3Å
594W98.5Very high97.6Very high192 Ų19278.4 Ų78.473%0.72739%0.389SS*.Hα-helixtrans-63.8-50.6-178.3-175.8-85000112.1W592 F596 Q597 C598W592-W594 VanDerWaalsContact C-N 3.33Å; W592-W594 PolarHBondContact O-N 3.36Å; W592-W594 VanDerWaalsContact O-N 3.13Å; W594-F596 VanDerWaalsContact C-N 3.31Å; W594-F596 PolarHBondContact O-N 3.18Å; W594-Q597 PolarHBondContact O-N 3.46Å; W594-C598 PolarHBondContact O-N 3.3Å; W594-C598 PolarHBondContact O-SG 3.07Å
595Q98.7Very high97.3Very high66 Ų6680.8 Ų80.831%0.30840%0.404SS..Hα-helixtrans-65.1-37.7-175.7-60.987.6-2500111.6P524 W592 C598 I599P524-Q595 HydrophobicContact CB-CB 3.99Å; P524-Q595 HydrophobicContact CG-CB 3.89Å; P524-Q595 HydrophobicContact CG-CG 4.16Å; W592-Q595 HydrophobicContact CE3-CG 4.3Å; W592-Q595 PolarHBondContact O-N 3.11Å; W592-Q595 PolarHBondContact O-OE1 2.72Å; Q595-C598 PolarHBondContact O-N 3.41Å; Q595-I599 WeakPolarHBondContact O-CG1 3.43Å; Q595-I599 PolarHBondContact O-N 2.95Å
596F98.6Very high96.6Very high25 Ų2579.6 Ų79.611%0.1139%0.393CS..Hα-helixtrans-72.4-37.5177.8-72.53.4000111.7P524 K549 F552 H591 W592 W594 C598 I599 D600P524-F596 HydrophobicContact CB-CD1 4.36Å; P524-F596 HydrophobicContact CB-CE1 4.11Å; P524-F596 HydrophobicContact CG-CE1 4.46Å; K549-F596 HydrophobicContact CB-CD2 4.32Å; K549-F596 HydrophobicContact CB-CE1 4.16Å; K549-F596 HydrophobicContact CB-CE2 3.93Å; K549-F596 HydrophobicContact CB-CZ 3.84Å; K549-F596 HydrophobicContact CD-CB 4.47Å; K549-F596 HydrophobicContact CD-CD2 4.22Å; K549-F596 HydrophobicContact CD-CG 4.18Å; K549-F596 HydrophobicContact CG-CD1 3.76Å; K549-F596 HydrophobicContact CG-CD2 3.94Å; K549-F596 HydrophobicContact CG-CE1 3.83Å; K549-F596 HydrophobicContact CG-CE2 4.01Å; K549-F596 HydrophobicContact CG-CG 3.82Å; K549-F596 HydrophobicContact CG-CZ 3.96Å; K549-F596 WeakPolarHBondContact O-CZ 3.18Å; F552-F596 HydrophobicContact CB-CE1 4.22Å; F552-F596 HydrophobicContact CB-CZ 4.18Å; H591-F596 WeakPolarHBondContact O-CD2 3.41Å; H591-F596 WeakPolarHBondContact O-CE2 3.27Å; W592-F596 HydrophobicContact CB-CD1 3.7Å; W592-F596 HydrophobicContact CB-CD2 4.08Å; W592-F596 HydrophobicContact CB-CE1 3.56Å; W592-F596 HydrophobicContact CB-CE2 3.95Å; W592-F596 HydrophobicContact CB-CG 3.97Å; W592-F596 HydrophobicContact CB-CZ 3.69Å; W592-F596 AromaticContact CD1-CZ 3.83Å; W592-F596 HydrophobicContact CG-CE1 4.02Å; W592-F596 HydrophobicContact CG-CE2 4.5Å; W592-F596 AromaticContact CG-CZ 3.95Å; W592-F596 HydrophobicContact CG-CZ 3.95Å; W592-F596 PolarHBondContact O-N 2.93Å; W594-F596 VanDerWaalsContact C-N 3.31Å; W594-F596 PolarHBondContact O-N 3.18Å; F596-C598 VanDerWaalsContact C-N 3.34Å; F596-C598 PolarHBondContact O-N 2.99Å; F596-I599 HydrophobicContact CD1-CD1 4.32Å; F596-I599 WeakPolarHBondContact O-CB 3.28Å; F596-I599 PolarHBondContact O-N 2.93Å; F596-D600 PolarHBondContact O-N 3.32Å; F596-D600 VanDerWaalsContact O-OD2 3.09Å
597Q98.4Very high95.5Very high110 Ų11079.3 Ų79.351%0.51440%0.403SS..Hα-helixtrans-61-40.5170.7-76.2170.1-8.800112.2N593 W594 I599 D600 N601N593-Q597 WeakPolarHBondContact O-CB 3.39Å; N593-Q597 WeakPolarHBondContact O-CG 3.49Å; N593-Q597 PolarHBondContact O-N 3.3Å; W594-Q597 PolarHBondContact O-N 3.46Å; Q597-I599 VanDerWaalsContact C-N 3.3Å; Q597-I599 PolarHBondContact O-N 3Å; Q597-D600 PolarHBondContact O-N 2.99Å; Q597-N601 WeakPolarHBondContact O-CB 3.5Å; Q597-N601 VanDerWaalsContact O-CG 3.23Å; Q597-N601 PolarHBondContact O-N 3.08Å; Q597-N601 PolarHBondContact O-ND2 3.1Å
598C98.4Very high93.7Very high37 Ų3776.6 Ų76.625%0.2540%0.403CS..Hα-helixtrans-60.1-40.4174.3-65.60000112.3F525 W594 Q595 F596 Q602F525-C598 HydrophobicContact CD2-CB 3.7Å; F525-C598 HydrophobicContact CE2-CB 4.08Å; F525-C598 WeakPolarHBondContact CE2-O 3.49Å; F525-C598 HydrophobicContact CG-CB 4.25Å; W594-C598 PolarHBondContact O-N 3.3Å; W594-C598 PolarHBondContact O-SG 3.07Å; Q595-C598 PolarHBondContact O-N 3.41Å; F596-C598 VanDerWaalsContact C-N 3.34Å; F596-C598 PolarHBondContact O-N 2.99Å; C598-Q602 WeakPolarHBondContact O-CB 3.32Å; C598-Q602 PolarHBondContact O-N 2.61Å; C598-Q602 VanDerWaalsContact O-N 3.09Å
599I98.4Very high91.6Very high0 Ų079 Ų790%043%0.426CS..Hα-helixtrans-63.2-46175.7-66.9170000110.3P524 F525 F528 A545 V548 Q595 F596 Q597 Q602 I603P524-I599 HydrophobicContact CB-CD1 4.21Å; F525-I599 HydrophobicContact CB-CG1 4.47Å; F525-I599 HydrophobicContact CD2-CG1 3.93Å; F528-I599 HydrophobicContact CB-CD1 4.07Å; F528-I599 HydrophobicContact CB-CG1 4.04Å; F528-I599 HydrophobicContact CD1-CB 4.5Å; F528-I599 HydrophobicContact CD1-CG1 4.2Å; F528-I599 HydrophobicContact CD1-CG2 4.07Å; F528-I599 HydrophobicContact CD2-CG2 3.94Å; F528-I599 HydrophobicContact CE1-CG2 4.24Å; F528-I599 HydrophobicContact CE2-CG2 4.13Å; F528-I599 HydrophobicContact CG-CG1 4.14Å; F528-I599 HydrophobicContact CG-CG2 3.91Å; F528-I599 HydrophobicContact CZ-CG2 4.28Å; A545-I599 HydrophobicContact CB-CG2 3.48Å; A545-I599 VanDerWaalsContact CB-CG2 3.48Å; V548-I599 HydrophobicContact CG1-CD1 4.1Å; Q595-I599 WeakPolarHBondContact O-CG1 3.43Å; Q595-I599 PolarHBondContact O-N 2.95Å; F596-I599 HydrophobicContact CD1-CD1 4.32Å; F596-I599 WeakPolarHBondContact O-CB 3.28Å; F596-I599 PolarHBondContact O-N 2.93Å; Q597-I599 VanDerWaalsContact C-N 3.3Å; Q597-I599 PolarHBondContact O-N 3Å; I599-Q602 PolarHBondContact O-N 3.14Å; I599-I603 HydrophobicContact CG2-CD1 4.11Å; I599-I603 WeakPolarHBondContact O-CG1 3.35Å; I599-I603 PolarHBondContact O-N 3.2Å
600D97.9Very high89Confident68 Ų6880.3 Ų80.336%0.36444%0.44SS..Hα-helixtrans-63-45.8-179.9-67.8-36.8000112K549 F596 Q597 Q602 I603 S604K549-D600 IonicContact NZ-OD1 2.87Å; K549-D600 PolarHBondContact NZ-OD1 3.24Å; K549-D600 IonicContact NZ-OD2 3.56Å; K549-D600 PolarHBondContact NZ-OD2 3.25Å; F596-D600 PolarHBondContact O-N 3.32Å; F596-D600 VanDerWaalsContact O-OD2 3.09Å; Q597-D600 PolarHBondContact O-N 2.99Å; D600-Q602 VanDerWaalsContact C-N 3.26Å; D600-Q602 PolarHBondContact O-N 3.38Å; D600-I603 PolarHBondContact O-N 3.16Å; D600-I603 VanDerWaalsContact O-N 3.14Å; D600-S604 PolarHBondContact O-N 3.47Å; D600-S604 PolarHBondContact O-OG 3.26Å; D600-S604 VanDerWaalsContact O-OG 3.13Å
601N97.4Very high86.5Confident95 Ų9586 Ų8651%0.50847%0.469SS..Hα-helixtrans-58.5-39.9176-69.9-14.6000111.7Q597 S604 Q605Q597-N601 WeakPolarHBondContact O-CB 3.5Å; Q597-N601 VanDerWaalsContact O-CG 3.23Å; Q597-N601 PolarHBondContact O-N 3.08Å; Q597-N601 PolarHBondContact O-ND2 3.1Å; N601-S604 PolarHBondContact O-N 3.09Å; N601-Q605 VanDerWaalsContact O-CG 3.3Å; N601-Q605 WeakPolarHBondContact O-CG 3.42Å; N601-Q605 PolarHBondContact O-N 3.29Å
602Q96.8Very high83.9Confident69 Ų6989.2 Ų89.232%0.32249%0.49SS..Hα-helixtrans-66.9-40.6177.7-168.966.934.400111.5F525 F528 C598 I599 D600 S604 Q605 M606F525-Q602 HydrophobicContact CE2-CB 3.95Å; F525-Q602 HydrophobicContact CE2-CG 4.35Å; F525-Q602 HydrophobicContact CZ-CB 4.49Å; F528-Q602 HydrophobicContact CE1-CB 4.06Å; F528-Q602 HydrophobicContact CE1-CG 3.94Å; C598-Q602 WeakPolarHBondContact O-CB 3.32Å; C598-Q602 PolarHBondContact O-N 2.61Å; C598-Q602 VanDerWaalsContact O-N 3.09Å; I599-Q602 PolarHBondContact O-N 3.14Å; D600-Q602 VanDerWaalsContact C-N 3.26Å; D600-Q602 PolarHBondContact O-N 3.38Å; Q602-S604 VanDerWaalsContact C-N 3.35Å; Q602-Q605 PolarHBondContact O-N 3.33Å; Q602-M606 HydrophobicContact CG-CE 3.96Å; Q602-M606 WeakPolarHBondContact O-CG 3.46Å; Q602-M606 PolarHBondContact O-N 3.29Å
603I95.1Very high81.2Confident35 Ų3590.7 Ų90.718%0.17952%0.515CS..Hα-helixtrans-61.6-44.6174.2-71.1168.7000110.6F528 I542 A545 I599 D600 Q605 M606F528-I603 HydrophobicContact CE2-CD1 4.3Å; F528-I603 HydrophobicContact CE2-CG1 4.23Å; F528-I603 HydrophobicContact CZ-CD1 4.27Å; F528-I603 HydrophobicContact CZ-CG1 3.74Å; I542-I603 HydrophobicContact CG1-CG2 4.01Å; A545-I603 HydrophobicContact CB-CD1 3.29Å; I599-I603 HydrophobicContact CG2-CD1 4.11Å; I599-I603 WeakPolarHBondContact O-CG1 3.35Å; I599-I603 PolarHBondContact O-N 3.2Å; D600-I603 PolarHBondContact O-N 3.16Å; D600-I603 VanDerWaalsContact O-N 3.14Å; I603-Q605 PolarHBondContact O-N 3.45Å; I603-M606 PolarHBondContact O-N 2.89Å
604S93.1Very high78.4Confident102 Ų10293.6 Ų93.671%0.71353%0.531SS*.Hα-helixtrans-63.2-23.1179.4-580000113.7D600 N601 Q602D600-S604 PolarHBondContact O-N 3.47Å; D600-S604 PolarHBondContact O-OG 3.26Å; D600-S604 VanDerWaalsContact O-OG 3.13Å; N601-S604 PolarHBondContact O-N 3.09Å; Q602-S604 VanDerWaalsContact C-N 3.35Å
605Q90.6Very high75.6Confident142 Ų14294.3 Ų94.366%0.66454%0.542SS*.Hα-helixtrans-89.8-12176.8-69.4172.817.900113.3N601 Q602 I603N601-Q605 VanDerWaalsContact O-CG 3.3Å; N601-Q605 WeakPolarHBondContact O-CG 3.42Å; N601-Q605 PolarHBondContact O-N 3.29Å; Q602-Q605 PolarHBondContact O-N 3.33Å; I603-Q605 PolarHBondContact O-N 3.45Å
606M85.7Confident72.9Confident51 Ų5193.9 Ų93.925%0.25156%0.555SS.*SBendtrans-73134.2177.1-71.8-179.8-171.400109.6F528 I532 P541 Q602 I603 A608F528-M606 HydrophobicContact CE1-CE 4.05Å; F528-M606 HydrophobicContact CZ-CE 3.79Å; I532-M606 HydrophobicContact CD1-CE 3.63Å; P541-M606 HydrophobicContact CB-CE 4.46Å; P541-M606 HydrophobicContact CB-SD 3.63Å; P541-M606 HydrophobicContact CG-SD 3.8Å; Q602-M606 HydrophobicContact CG-CE 3.96Å; Q602-M606 WeakPolarHBondContact O-CG 3.46Å; Q602-M606 PolarHBondContact O-N 3.29Å; I603-M606 PolarHBondContact O-N 2.89Å; M606-A608 PolarHBondContact O-N 3.43Å
607P73.6Confident70.1Confident115 Ų115104 Ų10475%0.74759%0.593SS**PPolyproline II helixtrans-58.4136.9172.624-30.8000108.9S609P607-S609 PolarHBondContact O-N 2.75Å
608A60.3Low67Low96 Ų96107.3 Ų107.379%0.79361%0.613SS**PPolyproline II helixtrans-53.8119.7170.700000107.6M606M606-A608 PolarHBondContact O-N 3.43Å
609S53.9Low64.1Low96 Ų96114.6 Ų114.667%0.67164%0.643SS**PPolyproline II helixtrans-53.9132.1172.7-66.30000107.8P607 D611P607-S609 PolarHBondContact O-N 2.75Å; S609-D611 PolarHBondContact O-N 3.38Å
610P43.7Very low60.9Low121 Ų121127.5 Ų127.579%0.78670%0.704SS**PPolyproline II helixtrans-57.4127.7171.223.8-29.7000107N612P610-N612 PolarHBondContact O-N 3.08Å
611D44.7Very low59.1Low157 Ų157130.5 Ų130.584%0.8472%0.721SS**  trans-45139.6175.9-87.1-43.1000110.2S609 G613S609-D611 PolarHBondContact O-N 3.38Å; D611-G613 PolarHBondContact O-N 2.89Å
612N42.3Very low57.1Low177 Ų177132.4 Ų132.495%0.94773%0.732SS**  trans-66.262.1156.1-81.2-28.2000109P610P610-N612 PolarHBondContact O-N 3.08Å
613G42.2Very low54.9Low63 Ų63135.9 Ų135.965%0.64975%0.754SS**  trans-99.973.5171.800000109.1D611D611-G613 PolarHBondContact O-N 2.89Å
614D38.8Very low52.5Low149 Ų149141.8 Ų141.880%0.79779%0.788SS**  trans-156.668.7154.4-134.7-6.1000111.5
615Q39.5Very low50Low206 Ų206144.3 Ų144.396%0.96379%0.793SS**  trans-122.485151.5-85.4-169.2-9.900107.2
616G41.3Very low47.3Very low57 Ų57144.5 Ų144.559%0.58880%0.802SS**  trans159.176.7167.600000114.9
617R39.1Very low44.5Very low239 Ų239151.1 Ų151.190%0.90284%0.841SS**  trans172.398.1133.9-97.6167.5-175.4-1751.9110.9
618L33.9Very low42.3Very low179 Ų179153.9 Ų153.994%0.93785%0.848SS**  trans-132.482.8147.6-82.9168.3000106.4
619E37.7Very low40.8Very low190 Ų190158.8 Ų158.889%0.88885%0.853SS**  trans-103.2104148.9-80.8-176.3160.300105.7
620E32.2Very low39.6Very low271 Ų271164.5 Ų164.5100%1.26687%0.869SS**  -179.40129.7-99.6-175.1174.400110.2

Retrieved 620 of 620 residues in 183.4 ms (Link to these results)