A0A087XBC0_POEFO Loading...

Transmembrane protein 161B

AlphaFold DB , UniProt , Accession A0A087XBC0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 492 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M45.8Very low73.7Confident223 Ų22374.2 Ų74.2100%1.09943%0.428SS*.  0134.50-67.9-163.8-89.700107.8L3M1-L3 PolarHBondContact O-N 3.16Å; M1-L3 VanDerWaalsContact O-N 3.1Å
2A49.9Very low75.1Confident75 Ų7578 Ų7862%0.6244%0.441SS*.  trans-65.7110.6-172.900000110F4 G5A2-F4 PolarHBondContact O-N 3.2Å; A2-G5 PolarHBondContact O-N 2.87Å
3L55.8Low76.4Confident117 Ų11778.5 Ų78.561%0.61345%0.447SS*.THydrogen-bonded Turntrans-53.6-15.3-174.8-87.2147.2000115.5M1M1-L3 PolarHBondContact O-N 3.16Å; M1-L3 VanDerWaalsContact O-N 3.1Å
4F62.2Low77.6Confident75 Ų7574.4 Ų74.433%0.32942%0.422SS..THydrogen-bonded Turntrans-142.512.9-173.3-63.2-70.1000115A2 V6 Q7 L8 M133 I135A2-F4 PolarHBondContact O-N 3.2Å; F4-V6 PolarHBondContact O-N 2.78Å; F4-Q7 PolarHBondContact O-N 3.34Å; F4-L8 HydrophobicContact CB-CB 4.01Å; F4-L8 HydrophobicContact CB-CD1 4.09Å; F4-L8 WeakPolarHBondContact O-CB 3.23Å; F4-L8 PolarHBondContact O-N 3.3Å; F4-M133 HydrophobicContact CE1-CB 3.93Å; F4-M133 HydrophobicContact CE1-CE 3.66Å; F4-M133 HydrophobicContact CZ-CE 3.88Å; F4-I135 HydrophobicContact CB-CD1 4.26Å; F4-I135 HydrophobicContact CD1-CD1 3.68Å; F4-I135 HydrophobicContact CD1-CG1 3.81Å; F4-I135 HydrophobicContact CE1-CD1 4.47Å; F4-I135 HydrophobicContact CE1-CG1 4.22Å; F4-I135 HydrophobicContact CG-CD1 4.35Å
5G75.4Confident78.5Confident32 Ų3271.9 Ų71.933%0.3341%0.414SS..Hα-helixtrans-46.4-64.2-159.200000115.7A2 V9A2-G5 PolarHBondContact O-N 2.87Å; G5-V9 WeakPolarHBondContact O-CG2 3.31Å
6V82.5Confident79.3Confident66 Ų6671.1 Ų71.140%0.441%0.414SS..Hα-helixtrans-78.4-38.8-175.51790000111.9F4 L8 V9 V10 Y123F4-V6 PolarHBondContact O-N 2.78Å; V6-L8 VanDerWaalsContact C-N 3.33Å; V6-L8 PolarHBondContact O-N 2.81Å; V6-V9 WeakPolarHBondContact O-CB 3.47Å; V6-V9 PolarHBondContact O-N 3.37Å; V6-V10 WeakPolarHBondContact O-CG2 3.44Å; V6-V10 PolarHBondContact O-N 2.87Å; V6-Y123 HydrophobicContact CB-CE1 4.19Å; V6-Y123 HydrophobicContact CB-CE2 4Å; V6-Y123 HydrophobicContact CG1-CD2 4.07Å; V6-Y123 HydrophobicContact CG1-CE1 4.47Å; V6-Y123 HydrophobicContact CG1-CE2 3.93Å; V6-Y123 HydrophobicContact CG1-CG 4.42Å; V6-Y123 HydrophobicContact CG2-CE2 3.96Å
7Q83.6Confident79.9Confident2 Ų269.6 Ų69.61%0.00941%0.407CS..Hα-helixtrans-68.7-32.8-176.4-60.5-174.77.600112.8F4 V10 T11 T120 Y123 Y124 M133 I135F4-Q7 PolarHBondContact O-N 3.34Å; Q7-V10 PolarHBondContact O-N 3.27Å; Q7-T11 WeakPolarHBondContact O-CB 3.21Å; Q7-T11 PolarHBondContact O-N 3.33Å; Q7-T11 PolarHBondContact O-OG1 3.39Å; Q7-T120 HydrophobicContact CG-CG2 4.4Å; Q7-Y123 HydrophobicContact CG-CD1 4.41Å; Q7-Y123 HydrophobicContact CG-CE1 4.28Å; Q7-Y124 PolarHBondContact NE2-OH 3.33Å; Q7-M133 PolarHBondContact OE1-O 3.23Å; Q7-I135 HydrophobicContact CB-CB 4.21Å; Q7-I135 HydrophobicContact CB-CD1 3.56Å; Q7-I135 HydrophobicContact CB-CG1 3.91Å
8L85.9Confident80.5Confident79 Ų7966.9 Ų66.941%0.41439%0.39SS..Hα-helixtrans-67.9-39.9174.6-167.3150.4000110.4F4 V6 T11 M12 I135F4-L8 HydrophobicContact CB-CB 4.01Å; F4-L8 HydrophobicContact CB-CD1 4.09Å; F4-L8 WeakPolarHBondContact O-CB 3.23Å; F4-L8 PolarHBondContact O-N 3.3Å; V6-L8 VanDerWaalsContact C-N 3.33Å; V6-L8 PolarHBondContact O-N 2.81Å; L8-T11 WeakPolarHBondContact O-CB 3.35Å; L8-T11 PolarHBondContact O-N 3.15Å; L8-M12 HydrophobicContact CD2-CG 3.85Å; L8-M12 HydrophobicContact CD2-SD 3.4Å; L8-M12 WeakPolarHBondContact CD2-SD 3.16Å; L8-M12 WeakPolarHBondContact O-CG 3.47Å; L8-M12 PolarHBondContact O-N 3.25Å; L8-I135 HydrophobicContact CB-CD1 4.32Å
9V89.4Confident80.9Confident84 Ų8471.1 Ų71.151%0.50941%0.405SS..Hα-helixtrans-60.5-48173.3175.80000110.6G5 V6 T11 M12 V13G5-V9 WeakPolarHBondContact O-CG2 3.31Å; V6-V9 WeakPolarHBondContact O-CB 3.47Å; V6-V9 PolarHBondContact O-N 3.37Å; V9-T11 VanDerWaalsContact C-N 3.27Å; V9-T11 PolarHBondContact O-N 3.16Å; V9-M12 PolarHBondContact O-N 2.87Å; V9-V13 HydrophobicContact CG1-CG2 4.26Å; V9-V13 WeakPolarHBondContact O-CB 3.33Å; V9-V13 VanDerWaalsContact O-CG2 3.29Å; V9-V13 WeakPolarHBondContact O-CG2 3.46Å; V9-V13 PolarHBondContact O-N 3.47Å
10V89.2Confident81.4Confident29 Ų2975.3 Ų75.318%0.17642%0.418CS..Hα-helixtrans-56.8-43.4176.1173.70000111.1V6 Q7 V13 M14 V116 I119V6-V10 WeakPolarHBondContact O-CG2 3.44Å; V6-V10 PolarHBondContact O-N 2.87Å; Q7-V10 PolarHBondContact O-N 3.27Å; V10-V13 PolarHBondContact O-N 2.72Å; V10-M14 WeakPolarHBondContact O-CB 3.25Å; V10-M14 PolarHBondContact O-N 2.74Å; V10-V116 HydrophobicContact CG1-CG1 4.28Å; V10-V116 HydrophobicContact CG1-CG2 4.43Å; V10-I119 HydrophobicContact CG1-CB 4.44Å; V10-I119 HydrophobicContact CG1-CG2 4.02Å; V10-I119 HydrophobicContact CG2-CG2 3.96Å
11T90.9Very high81.7Confident34 Ų3475.6 Ų75.621%0.20942%0.419CS..Hα-helixtrans-63.9-44.2177.4-64.80000112.1Q7 L8 V9 M14 A15 I135 W139Q7-T11 WeakPolarHBondContact O-CB 3.21Å; Q7-T11 PolarHBondContact O-N 3.33Å; Q7-T11 PolarHBondContact O-OG1 3.39Å; L8-T11 WeakPolarHBondContact O-CB 3.35Å; L8-T11 PolarHBondContact O-N 3.15Å; V9-T11 VanDerWaalsContact C-N 3.27Å; V9-T11 PolarHBondContact O-N 3.16Å; T11-M14 PolarHBondContact O-N 3.26Å; T11-A15 WeakPolarHBondContact O-CB 3.42Å; T11-A15 PolarHBondContact O-N 2.93Å; T11-I135 WeakPolarHBondContact OG1-CG2 3.3Å; T11-W139 HydrophobicContact CG2-CZ2 3.82Å; T11-W139 PolarHBondContact OG1-NE1 3.33Å
12M90.4Very high83.5Confident120 Ų12066.1 Ų66.159%0.59137%0.372SS*.Hα-helixtrans-67-39.7178.1-71.8-175.7104.600112.3L8 V9 A15 S16L8-M12 HydrophobicContact CD2-CG 3.85Å; L8-M12 HydrophobicContact CD2-SD 3.4Å; L8-M12 WeakPolarHBondContact CD2-SD 3.16Å; L8-M12 WeakPolarHBondContact O-CG 3.47Å; L8-M12 PolarHBondContact O-N 3.25Å; V9-M12 PolarHBondContact O-N 2.87Å; M12-A15 PolarHBondContact O-N 2.91Å; M12-S16 PolarHBondContact O-N 3.03Å; M12-S16 PolarHBondContact O-OG 3.29Å
13V92.6Very high85.1Confident84 Ų8466.2 Ų66.251%0.50937%0.367SS..Hα-helixtrans-62.5-48.7173.8172.10000109.4V9 V10 A15 S16 V17V9-V13 HydrophobicContact CG1-CG2 4.26Å; V9-V13 WeakPolarHBondContact O-CB 3.33Å; V9-V13 VanDerWaalsContact O-CG2 3.29Å; V9-V13 WeakPolarHBondContact O-CG2 3.46Å; V9-V13 PolarHBondContact O-N 3.47Å; V10-V13 PolarHBondContact O-N 2.72Å; V13-A15 VanDerWaalsContact C-N 3.35Å; V13-A15 PolarHBondContact O-N 3.33Å; V13-S16 WeakPolarHBondContact O-CB 3.37Å; V13-S16 PolarHBondContact O-N 3.49Å; V13-S16 VanDerWaalsContact O-N 3.1Å; V13-V17 HydrophobicContact CG1-CG2 4.48Å; V13-V17 WeakPolarHBondContact O-CG2 3.38Å; V13-V17 PolarHBondContact O-N 3.41Å
14M92.2Very high86.4Confident22 Ų2267.1 Ų67.111%0.10837%0.367CS..Hα-helixtrans-64.1-39179-169.960.668.500112.3V10 T11 S16 V17 I18 A112 A115 V116 W139V10-M14 WeakPolarHBondContact O-CB 3.25Å; V10-M14 PolarHBondContact O-N 2.74Å; T11-M14 PolarHBondContact O-N 3.26Å; M14-S16 VanDerWaalsContact C-N 3.28Å; M14-S16 PolarHBondContact O-N 2.92Å; M14-V17 WeakPolarHBondContact O-CB 3.49Å; M14-V17 PolarHBondContact O-N 3.42Å; M14-V17 HydrophobicContact SD-CB 4.17Å; M14-V17 HydrophobicContact SD-CG1 4.11Å; M14-I18 HydrophobicContact CG-CD1 4.24Å; M14-I18 WeakPolarHBondContact O-CG1 3.47Å; M14-I18 PolarHBondContact O-N 2.86Å; M14-A112 HydrophobicContact CG-CB 4.02Å; M14-A112 HydrophobicContact SD-CB 3.73Å; M14-A115 HydrophobicContact CE-CB 3.85Å; M14-V116 HydrophobicContact CB-CG2 3.62Å; M14-V116 HydrophobicContact CE-CG2 3.86Å; M14-V116 HydrophobicContact CG-CG2 3.52Å; M14-W139 HydrophobicContact CB-CH2 4.16Å; M14-W139 HydrophobicContact CB-CZ2 4.28Å; M14-W139 HydrophobicContact CG-CH2 3.85Å; M14-W139 HydrophobicContact CG-CZ2 4.39Å; M14-W139 HydrophobicContact CG-CZ3 4.31Å
15A91Very high87.5Confident36 Ų3672.3 Ų72.330%0.29839%0.386SS..Hα-helixtrans-60.2-39.9173.400000111.6T11 M12 V13 I18 Q19T11-A15 WeakPolarHBondContact O-CB 3.42Å; T11-A15 PolarHBondContact O-N 2.93Å; M12-A15 PolarHBondContact O-N 2.91Å; V13-A15 VanDerWaalsContact C-N 3.35Å; V13-A15 PolarHBondContact O-N 3.33Å; A15-I18 PolarHBondContact O-N 3.35Å; A15-Q19 WeakPolarHBondContact O-CG 3.47Å; A15-Q19 PolarHBondContact O-N 3.26Å
16S91.4Very high88.1Confident60 Ų6071.3 Ų71.342%0.4237%0.374SS..Hα-helixtrans-66.3-38.8174.7-58.70000112.3M12 V13 M14 Q19 K20M12-S16 PolarHBondContact O-N 3.03Å; M12-S16 PolarHBondContact O-OG 3.29Å; V13-S16 WeakPolarHBondContact O-CB 3.37Å; V13-S16 PolarHBondContact O-N 3.49Å; V13-S16 VanDerWaalsContact O-N 3.1Å; M14-S16 VanDerWaalsContact C-N 3.28Å; M14-S16 PolarHBondContact O-N 2.92Å; S16-Q19 PolarHBondContact O-N 3.41Å; S16-K20 WeakPolarHBondContact O-CB 3.25Å; S16-K20 PolarHBondContact O-N 3.2Å
17V90.2Very high88.4Confident46 Ų4672.2 Ų72.228%0.27937%0.373SS..Hα-helixtrans-61.6-46.7173.3167.50000110.4V13 M14 Q19 K20 I21 L22V13-V17 HydrophobicContact CG1-CG2 4.48Å; V13-V17 WeakPolarHBondContact O-CG2 3.38Å; V13-V17 PolarHBondContact O-N 3.41Å; M14-V17 WeakPolarHBondContact O-CB 3.49Å; M14-V17 PolarHBondContact O-N 3.42Å; M14-V17 HydrophobicContact SD-CB 4.17Å; M14-V17 HydrophobicContact SD-CG1 4.11Å; V17-Q19 VanDerWaalsContact C-N 3.3Å; V17-Q19 PolarHBondContact O-N 2.91Å; V17-K20 PolarHBondContact O-N 3Å; V17-I21 HydrophobicContact CB-CD1 4.36Å; V17-I21 HydrophobicContact CG1-CB 4.17Å; V17-I21 HydrophobicContact CG1-CD1 4.1Å; V17-I21 HydrophobicContact CG1-CG1 4.47Å; V17-I21 HydrophobicContact CG2-CD1 4.07Å; V17-I21 WeakPolarHBondContact O-CA 3.43Å; V17-I21 VanDerWaalsContact O-CB 3.28Å; V17-I21 WeakPolarHBondContact O-CB 3.35Å; V17-I21 PolarHBondContact O-N 2.85Å; V17-L22 PolarHBondContact O-N 3.46Å
18I90.3Very high88.6Confident21 Ų2172.1 Ų72.111%0.10837%0.372CS..Hα-helixtrans-59.4-41.7176.9-72.6169000111.1M14 A15 L22 W105 F109 A112 W139M14-I18 HydrophobicContact CG-CD1 4.24Å; M14-I18 WeakPolarHBondContact O-CG1 3.47Å; M14-I18 PolarHBondContact O-N 2.86Å; A15-I18 PolarHBondContact O-N 3.35Å; I18-L22 HydrophobicContact CG1-CD2 4.5Å; I18-L22 HydrophobicContact CG2-CD2 4.08Å; I18-L22 WeakPolarHBondContact O-CB 3.42Å; I18-W105 HydrophobicContact CG2-CH2 4.08Å; I18-W105 HydrophobicContact CG2-CZ3 3.97Å; I18-F109 HydrophobicContact CD1-CD2 4.14Å; I18-F109 HydrophobicContact CD1-CE2 4.37Å; I18-A112 HydrophobicContact CD1-CB 3.9Å; I18-A112 HydrophobicContact CG1-CB 4.03Å; I18-W139 HydrophobicContact CD1-CH2 3.79Å; I18-W139 HydrophobicContact CD1-CZ3 3.78Å
19Q89.4Confident88.8Confident145 Ų14570.1 Ų70.168%0.67836%0.359SS*.Hα-helixtrans-75.7-38.9-178.2-71.7176.2-1.800113.4A15 S16 V17 P23A15-Q19 WeakPolarHBondContact O-CG 3.47Å; A15-Q19 PolarHBondContact O-N 3.26Å; S16-Q19 PolarHBondContact O-N 3.41Å; V17-Q19 VanDerWaalsContact C-N 3.3Å; V17-Q19 PolarHBondContact O-N 2.91Å; Q19-P23 WeakPolarHBondContact O-CG 3.37Å
20K90.3Very high88.8Confident155 Ų15572.7 Ų72.767%0.67436%0.36SS*.Hα-helixtrans-98.9-38.1-171.8-65.7-173.3175.8-177.40113.9S16 V17 H24S16-K20 WeakPolarHBondContact O-CB 3.25Å; S16-K20 PolarHBondContact O-N 3.2Å; V17-K20 PolarHBondContact O-N 3Å; K20-H24 PolarHBondContact O-ND1 3.35Å
21I86.7Confident88.7Confident82 Ų8271.7 Ų71.742%0.42135%0.354SS..THydrogen-bonded Turntrans-94.8-42.7-171-58.6-176.7000111.1V17 P23 H24 Y25V17-I21 HydrophobicContact CB-CD1 4.36Å; V17-I21 HydrophobicContact CG1-CB 4.17Å; V17-I21 HydrophobicContact CG1-CD1 4.1Å; V17-I21 HydrophobicContact CG1-CG1 4.47Å; V17-I21 HydrophobicContact CG2-CD1 4.07Å; V17-I21 WeakPolarHBondContact O-CA 3.43Å; V17-I21 VanDerWaalsContact O-CB 3.28Å; V17-I21 WeakPolarHBondContact O-CB 3.35Å; V17-I21 PolarHBondContact O-N 2.85Å; I21-P23 VanDerWaalsContact C-CD 3.43Å; I21-P23 VanDerWaalsContact C-N 3.35Å; I21-H24 WeakPolarHBondContact O-CA 3.24Å; I21-H24 PolarHBondContact O-N 2.81Å; I21-Y25 HydrophobicContact CG2-CD2 4.08Å; I21-Y25 PolarHBondContact O-N 3.13Å
22L84.4Confident88.5Confident24 Ų2470.1 Ų70.113%0.12634%0.344CS..THydrogen-bonded Turntrans-55.8-37.3-176.5-136.370.4000115.1V17 I18 H24 Y25 W105 D108V17-L22 PolarHBondContact O-N 3.46Å; I18-L22 HydrophobicContact CG1-CD2 4.5Å; I18-L22 HydrophobicContact CG2-CD2 4.08Å; I18-L22 WeakPolarHBondContact O-CB 3.42Å; L22-H24 PolarHBondContact O-N 2.72Å; L22-Y25 CarbonylContact O-C 3.56Å; L22-W105 HydrophobicContact CD2-CZ3 4.43Å; L22-D108 HydrophobicContact CD1-CB 3.72Å; L22-D108 HydrophobicContact CD2-CB 3.63Å; L22-D108 HydrophobicContact CG-CB 3.74Å
23P82.9Confident88.3Confident78 Ų7865.7 Ų65.751%0.50632%0.324SS..THydrogen-bonded Turntrans-62.6-28.9173.8-24.135.2000113.2Q19 I21 R29Q19-P23 WeakPolarHBondContact O-CG 3.37Å; I21-P23 VanDerWaalsContact C-CD 3.43Å; I21-P23 VanDerWaalsContact C-N 3.35Å; P23-R29 PolarHBondContact O-NH2 2.84Å
24H83.8Confident87.7Confident135 Ų13563.8 Ų63.863%0.62532%0.315SS*.THydrogen-bonded Turntrans-93.7-43.9-176.8-59.784.7000111.7K20 I21 L22 R29K20-H24 PolarHBondContact O-ND1 3.35Å; I21-H24 WeakPolarHBondContact O-CA 3.24Å; I21-H24 PolarHBondContact O-N 2.81Å; L22-H24 PolarHBondContact O-N 2.72Å; H24-R29 PolarHBondContact O-NH2 3.21Å
25Y84.5Confident86.8Confident185 Ų18564.7 Ų64.773%0.72533%0.33SS*.  trans-121.9106.4-179.7-62.2-83.7000109.9I21 L22I21-Y25 HydrophobicContact CG2-CD2 4.08Å; I21-Y25 PolarHBondContact O-N 3.13Å; L22-Y25 CarbonylContact O-C 3.56Å
26S89Confident86.2Confident11 Ų1165.6 Ų65.68%0.07733%0.334CS..  trans-113.2126.9177.5168.60000110.1A28 R29 W30 Q104 D108S26-A28 VanDerWaalsContact C-N 3.26Å; S26-A28 WeakPolarHBondContact OG-CB 3.19Å; S26-A28 PolarHBondContact OG-N 2.83Å; S26-R29 PolarHBondContact O-N 2.81Å; S26-R29 PolarHBondContact OG-N 2.84Å; S26-W30 PolarHBondContact O-N 2.89Å; S26-W30 VanDerWaalsContact O-N 3.08Å; S26-Q104 WeakPolarHBondContact OG-CG 3.14Å; S26-D108 WeakPolarHBondContact CB-OD2 3.29Å; S26-D108 VanDerWaalsContact OG-CG 3.28Å; S26-D108 PolarHBondContact OG-OD1 2.88Å; S26-D108 PolarHBondContact OG-OD2 3.47Å
27F88.1Confident86Confident84 Ų8462.8 Ų62.837%0.36831%0.314SS..Hα-helixtrans-67.1-34.2174.5-172.2-102.9000110.5W30 L31 V107 D108 V111F27-W30 AromaticContact CD2-CE3 3.85Å; F27-W30 HydrophobicContact CD2-CE3 3.85Å; F27-W30 HydrophobicContact CD2-CZ3 4.27Å; F27-W30 HydrophobicContact CE2-CD2 4.48Å; F27-W30 AromaticContact CE2-CE3 3.48Å; F27-W30 HydrophobicContact CE2-CE3 3.48Å; F27-W30 VanDerWaalsContact CE2-CE3 3.48Å; F27-W30 HydrophobicContact CE2-CH2 4.38Å; F27-W30 AromaticContact CE2-CZ3 3.42Å; F27-W30 HydrophobicContact CE2-CZ3 3.42Å; F27-W30 VanDerWaalsContact CE2-CZ3 3.42Å; F27-W30 AromaticContact CZ-CE3 3.9Å; F27-W30 HydrophobicContact CZ-CE3 3.9Å; F27-W30 AromaticContact CZ-CZ3 3.58Å; F27-W30 HydrophobicContact CZ-CZ3 3.58Å; F27-W30 PolarHBondContact O-N 2.66Å; F27-L31 WeakPolarHBondContact O-CB 3.42Å; F27-L31 PolarHBondContact O-N 3.14Å; F27-V107 HydrophobicContact CB-CG1 4.37Å; F27-V107 HydrophobicContact CD1-CG1 3.56Å; F27-V107 HydrophobicContact CE1-CG1 4.39Å; F27-V107 HydrophobicContact CG-CG1 4.44Å; F27-D108 WeakPolarHBondContact CA-OD1 3.42Å; F27-D108 WeakPolarHBondContact CB-OD1 3.49Å; F27-D108 PolarHBondContact N-OD1 3.1Å; F27-V111 HydrophobicContact CB-CG2 4.32Å; F27-V111 HydrophobicContact CD1-CG2 3.82Å; F27-V111 HydrophobicContact CE1-CG2 4.36Å; F27-V111 HydrophobicContact CG-CG2 4.1Å
28A89.1Confident85.8Confident0 Ų067.2 Ų67.20%033%0.326CS..Hα-helixtrans-60.1-45173.500000112.5S26 L31 L32 F103 Q104 V107 D108S26-A28 VanDerWaalsContact C-N 3.26Å; S26-A28 WeakPolarHBondContact OG-CB 3.19Å; S26-A28 PolarHBondContact OG-N 2.83Å; A28-L31 WeakPolarHBondContact O-CB 3.22Å; A28-L31 PolarHBondContact O-N 2.66Å; A28-L32 PolarHBondContact O-N 3.32Å; A28-F103 HydrophobicContact CB-CD1 4.04Å; A28-F103 HydrophobicContact CB-CE1 3.78Å; A28-Q104 HydrophobicContact CB-CB 4.17Å; A28-Q104 HydrophobicContact CB-CG 4.15Å; A28-V107 HydrophobicContact CB-CB 3.82Å; A28-V107 HydrophobicContact CB-CG1 3.92Å; A28-V107 HydrophobicContact CB-CG2 4.39Å; A28-D108 PolarHBondContact N-OD1 2.87Å
29R88.7Confident85.7Confident38 Ų3867.4 Ų67.414%0.14333%0.325CS..Hα-helixtrans-62.7-45.1174.9-78.6-171.6-74.9143.83.8111.3P23 H24 S26 L31 L32 C33 E91 F100P23-R29 PolarHBondContact O-NH2 2.84Å; H24-R29 PolarHBondContact O-NH2 3.21Å; S26-R29 PolarHBondContact O-N 2.81Å; S26-R29 PolarHBondContact OG-N 2.84Å; R29-L31 VanDerWaalsContact C-N 3.27Å; R29-L31 PolarHBondContact O-N 3.46Å; R29-L32 PolarHBondContact O-N 2.9Å; R29-C33 VanDerWaalsContact O-CB 3.23Å; R29-C33 WeakPolarHBondContact O-CB 3.43Å; R29-C33 PolarHBondContact O-N 3.31Å; R29-C33 PolarHBondContact O-SG 2.99Å; R29-C33 VanDerWaalsContact O-SG 3.4Å; R29-E91 IonicContact NH1-OE2 3.33Å; R29-E91 PolarHBondContact NH1-OE2 2.88Å; R29-F100 HydrophobicContact CG-CE2 4.4Å; R29-F100 HydrophobicContact CG-CZ 3.75Å
30W89.5Confident85.6Confident137 Ų13762.2 Ų62.252%0.51930%0.3SS..Hα-helixtrans-59.1-39.1175.617582.7000112.6S26 F27 L32 S34 R330S26-W30 PolarHBondContact O-N 2.89Å; S26-W30 VanDerWaalsContact O-N 3.08Å; F27-W30 AromaticContact CD2-CE3 3.85Å; F27-W30 HydrophobicContact CD2-CE3 3.85Å; F27-W30 HydrophobicContact CD2-CZ3 4.27Å; F27-W30 HydrophobicContact CE2-CD2 4.48Å; F27-W30 AromaticContact CE2-CE3 3.48Å; F27-W30 HydrophobicContact CE2-CE3 3.48Å; F27-W30 VanDerWaalsContact CE2-CE3 3.48Å; F27-W30 HydrophobicContact CE2-CH2 4.38Å; F27-W30 AromaticContact CE2-CZ3 3.42Å; F27-W30 HydrophobicContact CE2-CZ3 3.42Å; F27-W30 VanDerWaalsContact CE2-CZ3 3.42Å; F27-W30 AromaticContact CZ-CE3 3.9Å; F27-W30 HydrophobicContact CZ-CE3 3.9Å; F27-W30 AromaticContact CZ-CZ3 3.58Å; F27-W30 HydrophobicContact CZ-CZ3 3.58Å; F27-W30 PolarHBondContact O-N 2.66Å; W30-L32 VanDerWaalsContact C-N 3.3Å; W30-L32 PolarHBondContact O-N 3.26Å; W30-S34 WeakPolarHBondContact O-CB 3.02Å; W30-S34 PolarHBondContact O-N 3.34Å; W30-S34 PolarHBondContact O-OG 3.47Å; W30-R330 VanDerWaalsContact CZ2-NH2 3.31Å
31L87.9Confident85.3Confident9 Ų956.9 Ų56.95%0.04728%0.277CS..Hα-helixtrans-64.1-34.4-179.7-166.460.6000112.4F27 A28 R29 F103 M329F27-L31 WeakPolarHBondContact O-CB 3.42Å; F27-L31 PolarHBondContact O-N 3.14Å; A28-L31 WeakPolarHBondContact O-CB 3.22Å; A28-L31 PolarHBondContact O-N 2.66Å; R29-L31 VanDerWaalsContact C-N 3.27Å; R29-L31 PolarHBondContact O-N 3.46Å; L31-F103 HydrophobicContact CD2-CZ 4.23Å; L31-M329 HydrophobicContact CD2-CE 3.61Å; L31-M329 HydrophobicContact CD2-SD 3.59Å; L31-M329 VanDerWaalsContact CD2-SD 3.59Å; L31-M329 HydrophobicContact CG-CE 4.23Å; L31-M329 HydrophobicContact CG-SD 4.27Å
32L87.2Confident85.1Confident0 Ų056.5 Ų56.50%027%0.274CS..Hα-helixtrans-91.7-38178.1-65.3179.5000114A28 R29 W30 L37 F100 F103 L333 L370A28-L32 PolarHBondContact O-N 3.32Å; R29-L32 PolarHBondContact O-N 2.9Å; W30-L32 VanDerWaalsContact C-N 3.3Å; W30-L32 PolarHBondContact O-N 3.26Å; L32-L37 HydrophobicContact CD2-CD1 4.02Å; L32-F100 HydrophobicContact CD1-CD2 4.5Å; L32-F100 HydrophobicContact CD1-CE2 4.38Å; L32-F103 HydrophobicContact CD1-CD1 3.88Å; L32-F103 HydrophobicContact CD1-CE1 3.48Å; L32-F103 VanDerWaalsContact CD1-CE1 3.48Å; L32-F103 HydrophobicContact CD1-CZ 4.28Å; L32-F103 HydrophobicContact CD2-CE1 4.38Å; L32-F103 HydrophobicContact CD2-CZ 4.43Å; L32-F103 HydrophobicContact CG-CE1 3.74Å; L32-F103 HydrophobicContact CG-CZ 4.21Å; L32-L333 HydrophobicContact CD2-CD1 3.98Å; L32-L370 HydrophobicContact CD2-CD2 4.41Å
33C84.8Confident85Confident27 Ų2755.6 Ų55.618%0.18227%0.269CS..Hα-helixtrans-101.93.9-166.9-550000114.7R29 G35 E91 T94R29-C33 VanDerWaalsContact O-CB 3.23Å; R29-C33 WeakPolarHBondContact O-CB 3.43Å; R29-C33 PolarHBondContact O-N 3.31Å; R29-C33 PolarHBondContact O-SG 2.99Å; R29-C33 VanDerWaalsContact O-SG 3.4Å; C33-G35 PolarHBondContact O-N 2.88Å; C33-E91 HydrophobicContact CB-CG 4.44Å; C33-T94 WeakPolarHBondContact SG-CG2 3.09Å
34S79.9Confident85Confident45 Ų4554.6 Ų54.632%0.31526%0.262SS..SBendtrans-68.616.2-178.649.90000115.3W30 S36 R330W30-S34 WeakPolarHBondContact O-CB 3.02Å; W30-S34 PolarHBondContact O-N 3.34Å; W30-S34 PolarHBondContact O-OG 3.47Å; S34-S36 VanDerWaalsContact C-N 3.26Å; S34-S36 PolarHBondContact O-N 3.13Å; S34-R330 PolarHBondContact OG-NH1 2.8Å; S34-R330 PolarHBondContact OG-NH2 3.32Å; S34-R330 VanDerWaalsContact OG-NH2 3.1Å
35G73.6Confident84.7Confident40 Ų4053.1 Ų53.141%0.41226%0.255SS..SBendtrans79.7-6174.300000115.6C33C33-G35 PolarHBondContact O-N 2.88Å
36S79.3Confident84.2Confident56 Ų5649.4 Ų49.439%0.39225%0.248SC..  trans-80.7-25.1178.660.80000113.8S34 R330S34-S36 VanDerWaalsContact C-N 3.26Å; S34-S36 PolarHBondContact O-N 3.13Å; S36-R330 PolarHBondContact OG-NH1 2.88Å
37L86.6Confident83.8Confident1 Ų152.7 Ų52.71%0.00526%0.262CS..  trans-92.5129-178.7-68.2175.5000110.8L32 I89 L333 Q334 L337L32-L37 HydrophobicContact CD2-CD1 4.02Å; L37-I89 HydrophobicContact CB-CD1 3.64Å; L37-I89 HydrophobicContact CB-CG1 4.18Å; L37-I89 HydrophobicContact CD1-CD1 4.09Å; L37-I89 PolarHBondContact O-N 2.96Å; L37-L333 HydrophobicContact CD1-CB 4.43Å; L37-L333 HydrophobicContact CD1-CD1 4.24Å; L37-L333 HydrophobicContact CD2-CB 3.96Å; L37-Q334 HydrophobicContact CD2-CB 4.06Å; L37-L337 HydrophobicContact CB-CD1 4.21Å; L37-L337 HydrophobicContact CD2-CD1 4.34Å
38R87Confident83.3Confident139 Ų13948.7 Ų48.753%0.52524%0.244SC..EExtended strand (participates in β ladder)trans-118.7125.8177.2-61.8-175.8-173.4-179.52.5109.9K87 Q334 L337R38-K87 CarbonylContact C-O 3.52Å; R38-K87 VanDerWaalsContact CA-O 3.3Å; R38-K87 WeakPolarHBondContact CA-O 3.4Å; R38-Q334 PolarHBondContact O-NE2 3.3Å; R38-L337 WeakPolarHBondContact O-CD1 3.3Å
39W87.6Confident82.7Confident24 Ų2456.6 Ų56.69%0.09127%0.274CS..EExtended strand (participates in β ladder)trans-108.2160.1175.175.5-80000110.4Q41 T86 K87 L337 F367W39-Q41 HydrophobicContact CH2-CB 4.27Å; W39-Q41 HydrophobicContact CH2-CG 4.15Å; W39-Q41 HydrophobicContact CZ3-CB 4.4Å; W39-T86 WeakPolarHBondContact O-CA 3.46Å; W39-K87 PolarHBondContact N-O 2.59Å; W39-K87 PolarHBondContact O-N 3.24Å; W39-L337 HydrophobicContact CB-CD1 4.44Å; W39-L337 HydrophobicContact CB-CD2 4.04Å; W39-F367 HydrophobicContact CB-CD2 3.53Å; W39-F367 HydrophobicContact CB-CE2 3.96Å; W39-F367 HydrophobicContact CB-CG 4.35Å; W39-F367 AromaticContact CD1-CE2 3.87Å; W39-F367 HydrophobicContact CD2-CB 4.46Å; W39-F367 HydrophobicContact CD2-CD1 4.2Å; W39-F367 AromaticContact CD2-CD2 3.67Å; W39-F367 HydrophobicContact CD2-CD2 3.67Å; W39-F367 HydrophobicContact CD2-CE1 4.4Å; W39-F367 AromaticContact CD2-CE2 3.9Å; W39-F367 HydrophobicContact CD2-CE2 3.9Å; W39-F367 AromaticContact CD2-CG 3.84Å; W39-F367 HydrophobicContact CD2-CG 3.84Å; W39-F367 HydrophobicContact CD2-CZ 4.26Å; W39-F367 HydrophobicContact CE3-CB 3.76Å; W39-F367 AromaticContact CE3-CD1 3.91Å; W39-F367 HydrophobicContact CE3-CD1 3.91Å; W39-F367 AromaticContact CE3-CD2 3.85Å; W39-F367 HydrophobicContact CE3-CD2 3.85Å; W39-F367 HydrophobicContact CE3-CE2 4.45Å; W39-F367 AromaticContact CE3-CG 3.54Å; W39-F367 HydrophobicContact CE3-CG 3.54Å; W39-F367 AromaticContact CG-CD2 3.55Å; W39-F367 HydrophobicContact CG-CD2 3.55Å; W39-F367 AromaticContact CG-CE2 3.65Å; W39-F367 HydrophobicContact CG-CE2 3.65Å; W39-F367 HydrophobicContact CG-CG 4.21Å; W39-F367 HydrophobicContact CG-CZ 4.37Å; W39-F367 HydrophobicContact CH2-CD1 4.41Å; W39-F367 HydrophobicContact CZ2-CE1 4.5Å; W39-F367 HydrophobicContact CZ3-CB 4.27Å; W39-F367 HydrophobicContact CZ3-CD1 4.02Å; W39-F367 HydrophobicContact CZ3-CG 4.08Å
40Y86.1Confident82.3Confident36 Ų3659.8 Ų59.814%0.14129%0.294CS..EExtended strand (participates in β ladder)trans-98.6120.8-178.1-68.5-84.7000110.7L84 E85 T86 L337 N338 A340 Q341Y40-L84 HydrophobicContact CD1-CB 3.37Å; Y40-L84 HydrophobicContact CD1-CD1 3.98Å; Y40-L84 HydrophobicContact CD1-CG 4.33Å; Y40-L84 HydrophobicContact CE1-CB 4.14Å; Y40-L84 HydrophobicContact CG-CB 4.1Å; Y40-L84 HydrophobicContact CG-CD1 4.02Å; Y40-E85 WeakPolarHBondContact CA-O 3.3Å; Y40-T86 HydrophobicContact CD1-CG2 3.66Å; Y40-T86 HydrophobicContact CE1-CG2 3.37Å; Y40-T86 HydrophobicContact CG-CG2 4.5Å; Y40-L337 WeakPolarHBondContact CD2-O 3.36Å; Y40-N338 HydrophobicContact CE2-CB 4.5Å; Y40-N338 WeakPolarHBondContact CE2-OD1 3.47Å; Y40-A340 HydrophobicContact CD2-CB 4.02Å; Y40-A340 HydrophobicContact CG-CB 4.3Å; Y40-Q341 HydrophobicContact CE1-CB 4.03Å; Y40-Q341 HydrophobicContact CE1-CG 4.47Å; Y40-Q341 HydrophobicContact CE2-CB 4.12Å
41Q84.7Confident81.6Confident44 Ų4455.9 Ų55.921%0.20628%0.283CS..PPolyproline II helixtrans-71.4135.4177.6-169.7-179.3-19.400110.3W39 E85 K87W39-Q41 HydrophobicContact CH2-CB 4.27Å; W39-Q41 HydrophobicContact CH2-CG 4.15Å; W39-Q41 HydrophobicContact CZ3-CB 4.4Å; Q41-E85 PolarHBondContact N-O 2.86Å; Q41-K87 VanDerWaalsContact OE1-CD 3.31Å
42H83.3Confident80.6Confident74 Ų7456.4 Ų56.434%0.34329%0.289SS..PPolyproline II helixtrans-63132.8169.569.2-60.1000110.4Q360 I363H42-Q360 HydrophobicContact CB-CB 4.39Å; H42-Q360 HydrophobicContact CB-CG 4.36Å; H42-I363 HydrophobicContact CB-CG2 4.33Å
43P81.7Confident79.5Confident5 Ų558.6 Ų58.63%0.03231%0.311CS..PPolyproline II helixtrans-70.3146.7-177.529.2-36.4000111.4L48 L82 Q360 I363P43-L48 HydrophobicContact CB-CD2 4.05Å; P43-L48 HydrophobicContact CB-CG 4.01Å; P43-L48 HydrophobicContact CG-CD1 4.01Å; P43-L48 HydrophobicContact CG-CD2 3.73Å; P43-L48 HydrophobicContact CG-CG 3.91Å; P43-L82 HydrophobicContact CB-CD1 3.98Å; P43-L82 HydrophobicContact CG-CD1 4.14Å; P43-L82 HydrophobicContact CG-CD2 4.02Å; P43-Q360 PolarHBondContact O-NE2 2.87Å; P43-I363 HydrophobicContact CG-CD1 4.38Å
44T81.9Confident78.3Confident57 Ų5765.7 Ų65.735%0.3534%0.339SS..PPolyproline II helixtrans-71.5154.4177.156.50000111.3D46 E47 L48T44-D46 PolarHBondContact O-N 3.16Å; T44-E47 PolarHBondContact N-OE2 3.23Å; T44-E47 PolarHBondContact O-N 3.39Å; T44-E47 WeakPolarHBondContact OG1-CB 3.35Å; T44-E47 VanDerWaalsContact OG1-CG 3.23Å; T44-E47 WeakPolarHBondContact OG1-CG 3.44Å; T44-E47 PolarHBondContact OG1-N 2.92Å; T44-E47 PolarHBondContact OG1-OE1 3.47Å; T44-L48 WeakPolarHBondContact O-CG 3.28Å; T44-L48 PolarHBondContact O-N 2.83Å
45E77.5Confident77Confident103 Ų10367.3 Ų67.348%0.48134%0.342SS..Hα-helixtrans-58.8-33.9177.3-69.5-168.5169.800111.7L48 R49E45-L48 PolarHBondContact O-N 3.49Å; E45-R49 WeakPolarHBondContact O-CB 3.28Å; E45-R49 PolarHBondContact O-N 3.35Å
46D75.9Confident75.8Confident108 Ų10871.4 Ų71.458%0.57835%0.348SS*.Hα-helixtrans-68.9-42.5177.7-68.4-38.2000112.4T44 R49 N50T44-D46 PolarHBondContact O-N 3.16Å; D46-R49 PolarHBondContact O-N 2.8Å; D46-N50 VanDerWaalsContact O-CB 3.31Å; D46-N50 WeakPolarHBondContact O-CB 3.39Å; D46-N50 PolarHBondContact O-N 3.31Å; D46-N50 PolarHBondContact O-ND2 3.43Å; D46-N50 VanDerWaalsContact O-ND2 3.16Å
47E78.8Confident74.1Confident79 Ų7972.2 Ų72.237%0.36937%0.365SS..Hα-helixtrans-59.8-48172.4-79.9158.2-143.700111.5T44 R49 N50 L51T44-E47 PolarHBondContact N-OE2 3.23Å; T44-E47 PolarHBondContact O-N 3.39Å; T44-E47 WeakPolarHBondContact OG1-CB 3.35Å; T44-E47 VanDerWaalsContact OG1-CG 3.23Å; T44-E47 WeakPolarHBondContact OG1-CG 3.44Å; T44-E47 PolarHBondContact OG1-N 2.92Å; T44-E47 PolarHBondContact OG1-OE1 3.47Å; E47-R49 VanDerWaalsContact C-N 3.3Å; E47-R49 PolarHBondContact O-N 3.35Å; E47-N50 PolarHBondContact O-N 3.5Å; E47-L51 WeakPolarHBondContact O-CB 3.23Å; E47-L51 WeakPolarHBondContact O-CG 3.36Å; E47-L51 PolarHBondContact O-N 2.87Å
48L79.2Confident72.2Confident0 Ų080.8 Ų80.80%041%0.405CS..Hα-helixtrans-61.8-40.1178-70.6176.7000111.5P43 T44 E45 A52 V76 L82 T356 L359P43-L48 HydrophobicContact CB-CD2 4.05Å; P43-L48 HydrophobicContact CB-CG 4.01Å; P43-L48 HydrophobicContact CG-CD1 4.01Å; P43-L48 HydrophobicContact CG-CD2 3.73Å; P43-L48 HydrophobicContact CG-CG 3.91Å; T44-L48 WeakPolarHBondContact O-CG 3.28Å; T44-L48 PolarHBondContact O-N 2.83Å; E45-L48 PolarHBondContact O-N 3.49Å; L48-A52 WeakPolarHBondContact O-CB 3.38Å; L48-A52 PolarHBondContact O-N 2.89Å; L48-V76 HydrophobicContact CB-CG2 4.31Å; L48-L82 HydrophobicContact CD2-CD1 4.16Å; L48-L82 HydrophobicContact CD2-CD2 4.45Å; L48-T356 HydrophobicContact CB-CG2 4.29Å; L48-T356 HydrophobicContact CD1-CG2 3.72Å; L48-L359 HydrophobicContact CD1-CD2 4.23Å; L48-L359 HydrophobicContact CD2-CD2 3.81Å
49R75.8Confident70.3Confident166 Ų16684 Ų8463%0.62642%0.423SS*.Hα-helixtrans-67-41.2177.3-173.2177.1-179-176.80.1111.9E45 D46 E47 G53 L74E45-R49 WeakPolarHBondContact O-CB 3.28Å; E45-R49 PolarHBondContact O-N 3.35Å; D46-R49 PolarHBondContact O-N 2.8Å; E47-R49 VanDerWaalsContact C-N 3.3Å; E47-R49 PolarHBondContact O-N 3.35Å; R49-G53 PolarHBondContact O-N 3.15Å; R49-L74 HydrophobicContact CB-CD2 4.41Å
50N79.4Confident68.1Low106 Ų10692.6 Ų92.657%0.56746%0.455SS*.Hα-helixtrans-66-44.1177.8-73.6-25.4000111.7D46 E47 G53 K54D46-N50 VanDerWaalsContact O-CB 3.31Å; D46-N50 WeakPolarHBondContact O-CB 3.39Å; D46-N50 PolarHBondContact O-N 3.31Å; D46-N50 PolarHBondContact O-ND2 3.43Å; D46-N50 VanDerWaalsContact O-ND2 3.16Å; E47-N50 PolarHBondContact O-N 3.5Å; N50-G53 PolarHBondContact O-N 3.41Å; N50-K54 WeakPolarHBondContact O-CG 3.42Å; N50-K54 PolarHBondContact O-N 3.47Å; N50-K54 VanDerWaalsContact O-N 3.15Å
51L74.8Confident65.9Low55 Ų55100.5 Ų100.529%0.28849%0.491SS..Hα-helixtrans-68.4-41.4177.7-71.4170.8000111.8E47 G53 K54 Q55 I80 L82E47-L51 WeakPolarHBondContact O-CB 3.23Å; E47-L51 WeakPolarHBondContact O-CG 3.36Å; E47-L51 PolarHBondContact O-N 2.87Å; L51-G53 VanDerWaalsContact C-N 3.29Å; L51-G53 PolarHBondContact O-N 2.87Å; L51-K54 PolarHBondContact O-N 3.4Å; L51-Q55 PolarHBondContact O-N 2.97Å; L51-I80 HydrophobicContact CB-CD1 3.56Å; L51-I80 HydrophobicContact CB-CG1 3.91Å; L51-L82 HydrophobicContact CD1-CD1 3.99Å
52A68.3Low63.9Low20 Ų20105.8 Ų105.817%0.16552%0.52CS..Hα-helixtrans-67.3-30.9175.400000112.6L48 V76 I80L48-A52 WeakPolarHBondContact O-CB 3.38Å; L48-A52 PolarHBondContact O-N 2.89Å; A52-V76 HydrophobicContact CB-CG1 4.06Å; A52-V76 HydrophobicContact CB-CG2 4.38Å; A52-I80 HydrophobicContact CB-CD1 4.05Å
53G63.6Low61.9Low45 Ų45114 Ų11446%0.46455%0.548SS..Hα-helixtrans-68-37.2174.900000112.8R49 N50 L51 K56R49-G53 PolarHBondContact O-N 3.15Å; N50-G53 PolarHBondContact O-N 3.41Å; L51-G53 VanDerWaalsContact C-N 3.29Å; L51-G53 PolarHBondContact O-N 2.87Å; G53-K56 PolarHBondContact O-N 3.19Å
54K59Low60.2Low177 Ų177123.7 Ų123.777%0.7759%0.59SS**Hα-helixtrans-69.9-29.8178.5-75.2174.5177.5179.70113.6N50 L51 K56N50-K54 WeakPolarHBondContact O-CG 3.42Å; N50-K54 PolarHBondContact O-N 3.47Å; N50-K54 VanDerWaalsContact O-N 3.15Å; L51-K54 PolarHBondContact O-N 3.4Å; K54-K56 VanDerWaalsContact C-N 3.29Å; K54-K56 PolarHBondContact O-N 3.01Å
55Q53.4Low58.2Low79 Ų79131.6 Ų131.637%0.36962%0.615SS.*THydrogen-bonded Turntrans-75.7-12.3175-79.1-173.8-27.400114.1L51 G57 D79L51-Q55 PolarHBondContact O-N 2.97Å; Q55-G57 PolarHBondContact O-N 2.94Å; Q55-D79 PolarHBondContact NE2-O 2.57Å
56K48.2Very low56.4Low126 Ų126133.4 Ų133.455%0.54863%0.628SS.*  trans-77.986173.1-96-179.5177.5164.90111G53 K54 Q58G53-K56 PolarHBondContact O-N 3.19Å; K54-K56 VanDerWaalsContact C-N 3.29Å; K54-K56 PolarHBondContact O-N 3.01Å; K56-Q58 PolarHBondContact O-N 3.27Å
57G44.5Very low54.9Low73 Ų73132.6 Ų132.675%0.75365%0.645SS**  trans-60.9112.4151.900000109.8Q55Q55-G57 PolarHBondContact O-N 2.94Å
58Q45.9Very low53.1Low181 Ų181135.9 Ų135.985%0.84666%0.66SS**SBendtrans48.1124.7161-82.7174.5-12.700120.9K56K56-Q58 PolarHBondContact O-N 3.27Å
59K47.3Very low51.5Low207 Ų207143.3 Ų143.390%0.970%0.698SS**  trans70.691.1157.7-64-178-179.5175.90117.3
60R40.1Very low49.9Very low203 Ų203139.1 Ų139.177%0.76669%0.688SS**  trans-104.1107.4150.1-149.2179.6-164.6-177.65.7108.8
61K41.7Very low48.6Very low203 Ų203141.9 Ų141.988%0.88370%0.703SS**  trans-71.1121.4170.8-153176.2-173.6179.30107.4R63K61-R63 PolarHBondContact O-N 2.89Å; K61-R63 VanDerWaalsContact O-N 3.16Å
62D40.8Very low47.8Very low154 Ų154146.6 Ų146.682%0.82472%0.721SS**  trans-59.2113.5177.8-75.5-47.3000110.8
63R41.8Very low47.8Very low248 Ų248148.8 Ų148.894%0.93673%0.734SS**  trans-106.691.2157.3-94.1-177.8169.8171.5-3.5107K61 Y65K61-R63 PolarHBondContact O-N 2.89Å; K61-R63 VanDerWaalsContact O-N 3.16Å; R63-Y65 PolarHBondContact O-N 3.34Å
64K46.3Very low48.4Very low208 Ų208150.4 Ų150.490%0.90473%0.731SS**  trans-60.5119.4159.1-90.4178.4174.1177.40107.3
65Y40Very low49.3Very low222 Ų222145.1 Ų145.187%0.87171%0.714SS**  trans-118.8139.2162.4-148.5-95.8000108.4R63R63-Y65 PolarHBondContact O-N 3.34Å
66N40.3Very low50.6Low141 Ų141141.4 Ų141.475%0.75470%0.697SS**  trans-37.5127.2-168.9-80.4-20.4000117H68N66-H68 VanDerWaalsContact C-N 3.26Å; N66-H68 PolarHBondContact O-N 3.08Å
67G44.5Very low52.1Low92 Ų92136.5 Ų136.595%0.94868%0.678SS**SBend66.1-3.8118.800000120.7
68H40.1Very low53.8Low147 Ų147134.9 Ų134.968%0.68165%0.65SS**  trans-113.8107.1174.3-153.3-71.7000108.9N66 D70N66-H68 VanDerWaalsContact C-N 3.26Å; N66-H68 PolarHBondContact O-N 3.08Å; H68-D70 IonicContact CE1-OD1 3.3Å; H68-D70 PolarHBondContact CE1-OD1 3.35Å; H68-D70 VanDerWaalsContact CE1-OD1 3.3Å; H68-D70 IonicContact CG-OD1 3.82Å; H68-D70 IonicContact ND1-OD1 2.78Å; H68-D70 PolarHBondContact ND1-OD1 3.3Å; H68-D70 PolarHBondContact O-N 3.4Å
69I45.8Very low55.2Low156 Ų156130.8 Ų130.880%0.863%0.634SS**  trans-73.281.3169.3-58.8173.3000106.2N71I69-N71 PolarHBondContact O-N 3.24Å
70D43.1Very low56.8Low79 Ų79121 Ų12142%0.42259%0.591SS.*  trans-65.3114.2160.7-80-8.6000106.7H68 K72H68-D70 IonicContact CE1-OD1 3.3Å; H68-D70 PolarHBondContact CE1-OD1 3.35Å; H68-D70 VanDerWaalsContact CE1-OD1 3.3Å; H68-D70 IonicContact CG-OD1 3.82Å; H68-D70 IonicContact ND1-OD1 2.78Å; H68-D70 PolarHBondContact ND1-OD1 3.3Å; H68-D70 PolarHBondContact O-N 3.4Å; D70-K72 HydrophobicContact CB-CD 3.98Å; D70-K72 HydrophobicContact CB-CG 4.07Å; D70-K72 PolarHBondContact O-N 2.77Å; D70-K72 WeakPolarHBondContact OD2-CE 3.35Å; D70-K72 IonicContact OD2-NZ 2.74Å; D70-K72 PolarHBondContact OD2-NZ 3.22Å
71N50.6Low58.4Low163 Ų163116 Ų11687%0.87258%0.58SS**  trans-63.952.5163.9-97.5-8.9000110.5I69I69-N71 PolarHBondContact O-N 3.24Å
72K59.4Low60.1Low155 Ų155106.6 Ų106.667%0.67454%0.539SS*.PPolyproline II helixtrans-74.8121.5172.6-86.6165.6178.7149.10107.2D70 L74D70-K72 HydrophobicContact CB-CD 3.98Å; D70-K72 HydrophobicContact CB-CG 4.07Å; D70-K72 PolarHBondContact O-N 2.77Å; D70-K72 WeakPolarHBondContact OD2-CE 3.35Å; D70-K72 IonicContact OD2-NZ 2.74Å; D70-K72 PolarHBondContact OD2-NZ 3.22Å; K72-L74 PolarHBondContact O-N 2.84Å
73P66.8Low61.8Low66 Ų66106.7 Ų106.743%0.42954%0.535SS..PPolyproline II helixtrans-57.6141.5-177.523.8-33.1000109.8T75 V357P73-T75 PolarHBondContact O-N 3.37Å; P73-V357 HydrophobicContact CB-CG2 4Å
74L76.7Confident63.8Low79 Ų7995.6 Ų95.641%0.41449%0.494SS..PPolyproline II helixtrans-54.8127.2-179.7-171.875000108.5R49 K72 T356R49-L74 HydrophobicContact CB-CD2 4.41Å; K72-L74 PolarHBondContact O-N 2.84Å; L74-T356 HydrophobicContact CB-CG2 4.03Å; L74-T356 HydrophobicContact CD2-CG2 4.02Å; L74-T356 HydrophobicContact CG-CG2 4.22Å; L74-T356 WeakPolarHBondContact O-CB 3.45Å; L74-T356 WeakPolarHBondContact O-CG2 3.48Å; L74-T356 PolarHBondContact O-N 3.45Å; L74-T356 PolarHBondContact O-OG1 3.31Å
75T77.9Confident65.5Low65 Ų6591.3 Ų91.340%0.39948%0.477SS..EExtended strand (participates in β ladder)trans-105.214217957.50000111.1P73 R353 I354P73-T75 PolarHBondContact O-N 3.37Å; T75-R353 PolarHBondContact O-NH2 2.92Å; T75-R353 PolarHBondContact OG1-NE 3.18Å; T75-R353 VanDerWaalsContact OG1-NE 3.13Å; T75-I354 CarbonylContact C-O 3.59Å; T75-I354 VanDerWaalsContact CA-O 3.25Å; T75-I354 WeakPolarHBondContact CA-O 3.07Å
76V81.3Confident67.6Low2 Ų284 Ų841%0.01246%0.456CS..EExtended strand (participates in β ladder)trans-125.2144.7-176175.50000109.1L48 A52 I80 R353 I354 T356L48-V76 HydrophobicContact CB-CG2 4.31Å; A52-V76 HydrophobicContact CB-CG1 4.06Å; A52-V76 HydrophobicContact CB-CG2 4.38Å; V76-I80 HydrophobicContact CG1-CB 4.16Å; V76-I80 HydrophobicContact CG1-CD1 3.32Å; V76-I80 HydrophobicContact CG1-CG1 4.37Å; V76-I80 HydrophobicContact CG1-CG2 4.12Å; V76-R353 WeakPolarHBondContact O-CA 3.18Å; V76-I354 PolarHBondContact N-O 2.89Å; V76-I354 PolarHBondContact O-N 3.31Å; V76-T356 HydrophobicContact CG2-CG2 3.54Å
77P79.6Confident69.8Low22 Ų2281.9 Ų81.914%0.14344%0.44CS..EExtended strand (participates in β ladder)trans-58.7140.6172.8-18.731.8000111.4D79 I80P77-D79 VanDerWaalsContact C-N 3.29Å; P77-D79 WeakPolarHBondContact CB-OD1 3.19Å; P77-D79 PolarHBondContact O-N 3.36Å; P77-I80 WeakPolarHBondContact O-CB 3.46Å; P77-I80 WeakPolarHBondContact O-CG2 3.49Å; P77-I80 PolarHBondContact O-N 3.39Å
78K79.3Confident71.7Confident39 Ų3980.5 Ų80.517%0.1742%0.415CS..THydrogen-bonded Turntrans-69.8-26.4-180-77.7-172.8173.6-171.90113.1I80 M347 K348 E350 G352 I354K78-I80 PolarHBondContact O-N 3.1Å; K78-M347 HydrophobicContact CB-CG 3.85Å; K78-M347 HydrophobicContact CD-CG 4.12Å; K78-M347 HydrophobicContact CG-CG 3.78Å; K78-M347 HydrophobicContact CG-SD 4.4Å; K78-K348 WeakPolarHBondContact O-CA 3.46Å; K78-E350 VanDerWaalsContact CB-O 3.3Å; K78-E350 WeakPolarHBondContact CB-O 3.26Å; K78-E350 HydrophobicContact CD-CB 3.96Å; K78-E350 IonicContact NZ-OE2 2.88Å; K78-E350 PolarHBondContact NZ-OE2 2.99Å; K78-G352 PolarHBondContact N-O 3.41Å; K78-I354 HydrophobicContact CG-CB 4.11Å; K78-I354 HydrophobicContact CG-CG2 4.29Å
79D76.9Confident73.8Confident95 Ų9573.7 Ų73.751%0.50838%0.383SS..THydrogen-bonded Turntrans-8113.7177.163.4-42.1000113.7Q55 P77 D81Q55-D79 PolarHBondContact NE2-O 2.57Å; P77-D79 VanDerWaalsContact C-N 3.29Å; P77-D79 WeakPolarHBondContact CB-OD1 3.19Å; P77-D79 PolarHBondContact O-N 3.36Å; D79-D81 PolarHBondContact O-N 3.01Å
80I79.2Confident75.6Confident1 Ų169.6 Ų69.61%0.00537%0.365CS..  trans-61132177.2-166.7161.4000110.6L51 A52 V76 P77 K78 L82 M347 K348L51-I80 HydrophobicContact CB-CD1 3.56Å; L51-I80 HydrophobicContact CB-CG1 3.91Å; A52-I80 HydrophobicContact CB-CD1 4.05Å; V76-I80 HydrophobicContact CG1-CB 4.16Å; V76-I80 HydrophobicContact CG1-CD1 3.32Å; V76-I80 HydrophobicContact CG1-CG1 4.37Å; V76-I80 HydrophobicContact CG1-CG2 4.12Å; P77-I80 WeakPolarHBondContact O-CB 3.46Å; P77-I80 WeakPolarHBondContact O-CG2 3.49Å; P77-I80 PolarHBondContact O-N 3.39Å; K78-I80 PolarHBondContact O-N 3.1Å; I80-L82 HydrophobicContact CG2-CB 4.19Å; I80-L82 PolarHBondContact O-N 3.38Å; I80-M347 HydrophobicContact CG2-CE 4.45Å; I80-K348 WeakPolarHBondContact O-CE 3.44Å
81D74.3Confident77.3Confident100 Ų10070.9 Ų70.954%0.53537%0.369SS..  trans-76.375.2175.6-167.126.4000111D79 K348D79-D81 PolarHBondContact O-N 3.01Å; D81-K348 IonicContact OD1-NZ 2.79Å; D81-K348 PolarHBondContact OD1-NZ 3.37Å
82L77.3Confident78.8Confident4 Ų468.4 Ų68.42%0.02136%0.36CS..  trans-87.9124.6176-175.967.6000109.4P43 L48 L51 I80 L84 V344 K348 L359 I363P43-L82 HydrophobicContact CB-CD1 3.98Å; P43-L82 HydrophobicContact CG-CD1 4.14Å; P43-L82 HydrophobicContact CG-CD2 4.02Å; L48-L82 HydrophobicContact CD2-CD1 4.16Å; L48-L82 HydrophobicContact CD2-CD2 4.45Å; L51-L82 HydrophobicContact CD1-CD1 3.99Å; I80-L82 HydrophobicContact CG2-CB 4.19Å; I80-L82 PolarHBondContact O-N 3.38Å; L82-L84 HydrophobicContact CD2-CD2 3.74Å; L82-L84 HydrophobicContact CG-CD2 4.05Å; L82-V344 HydrophobicContact CB-CG1 4.22Å; L82-V344 HydrophobicContact CD2-CG1 4.16Å; L82-V344 HydrophobicContact CD2-CG2 4.29Å; L82-K348 PolarHBondContact O-NZ 3.38Å; L82-L359 HydrophobicContact CD2-CD2 4.26Å; L82-I363 HydrophobicContact CD2-CD1 4.48Å
83Q77.8Confident79.8Confident156 Ų15663.2 Ų63.273%0.72934%0.339SS*.  trans-108.4118.7165.5-65.4-172.1-3.800107.4
84L81.7Confident80.4Confident16 Ų1660.1 Ų60.18%0.08432%0.319CS..PPolyproline II helixtrans-78.3130.8-178.6-63.6176.5000110Y40 L82 A340 V344 I363Y40-L84 HydrophobicContact CD1-CB 3.37Å; Y40-L84 HydrophobicContact CD1-CD1 3.98Å; Y40-L84 HydrophobicContact CD1-CG 4.33Å; Y40-L84 HydrophobicContact CE1-CB 4.14Å; Y40-L84 HydrophobicContact CG-CB 4.1Å; Y40-L84 HydrophobicContact CG-CD1 4.02Å; L82-L84 HydrophobicContact CD2-CD2 3.74Å; L82-L84 HydrophobicContact CG-CD2 4.05Å; L84-A340 HydrophobicContact CD1-CB 4.44Å; L84-V344 HydrophobicContact CD1-CB 4.49Å; L84-V344 HydrophobicContact CD1-CG2 3.82Å; L84-V344 HydrophobicContact CD2-CG2 4.34Å; L84-V344 HydrophobicContact CG-CG2 4.25Å; L84-I363 HydrophobicContact CD1-CD1 4.43Å; L84-I363 HydrophobicContact CD1-CG1 4.41Å; L84-I363 HydrophobicContact CD1-CG2 4.5Å; L84-I363 HydrophobicContact CD2-CD1 3.62Å; L84-I363 HydrophobicContact CD2-CG1 4.42Å
85E82.2Confident80.5Confident118 Ų11862.9 Ų62.955%0.55133%0.334SS*.PPolyproline II helixtrans-71138.2173-65.3-168.1168.600110.6Y40 Q41Y40-E85 WeakPolarHBondContact CA-O 3.3Å; Q41-E85 PolarHBondContact N-O 2.86Å
86T85.8Confident80.7Confident69 Ų6962.5 Ų62.542%0.42334%0.337SS..EExtended strand (participates in β ladder)trans-100132.6177.157.70000110.6W39 Y40W39-T86 WeakPolarHBondContact O-CA 3.46Å; Y40-T86 HydrophobicContact CD1-CG2 3.66Å; Y40-T86 HydrophobicContact CE1-CG2 3.37Å; Y40-T86 HydrophobicContact CG-CG2 4.5Å
87K85.7Confident81Confident96 Ų9662.8 Ų62.842%0.41734%0.339SS..EExtended strand (participates in β ladder)trans-122.8146.2173.9-75.9-174.2169.51740110.6R38 W39 Q41R38-K87 CarbonylContact C-O 3.52Å; R38-K87 VanDerWaalsContact CA-O 3.3Å; R38-K87 WeakPolarHBondContact CA-O 3.4Å; W39-K87 PolarHBondContact N-O 2.59Å; W39-K87 PolarHBondContact O-N 3.24Å; Q41-K87 VanDerWaalsContact OE1-CD 3.31Å
88C84.8Confident81.3Confident62 Ų6266.8 Ų66.842%0.41935%0.351SS..EExtended strand (participates in β ladder)trans-73.7145.8170.3-63.20000109.2T90C88-T90 PolarHBondContact O-N 3.19Å
89I84.5Confident81.8Confident5 Ų566.1 Ų66.13%0.02635%0.348CS..PPolyproline II helixtrans-71.1119.8176.8-56.9-179.8000108.8L37 T94 L337 F367 L370L37-I89 HydrophobicContact CB-CD1 3.64Å; L37-I89 HydrophobicContact CB-CG1 4.18Å; L37-I89 HydrophobicContact CD1-CD1 4.09Å; L37-I89 PolarHBondContact O-N 2.96Å; I89-T94 HydrophobicContact CG2-CG2 3.77Å; I89-L337 HydrophobicContact CD1-CD1 4.16Å; I89-F367 HydrophobicContact CD1-CE2 4.28Å; I89-F367 HydrophobicContact CG1-CE2 4.17Å; I89-L370 HydrophobicContact CD1-CD2 3.53Å
90T82.4Confident82.5Confident69 Ų6962 Ų6242%0.42333%0.326SS..PPolyproline II helixtrans-100.3161.2174.370.90000111.3C88 V92 D93 T94C88-T90 PolarHBondContact O-N 3.19Å; T90-V92 PolarHBondContact O-N 3.24Å; T90-D93 PolarHBondContact N-OD2 3.3Å; T90-D93 VanDerWaalsContact N-OD2 3.13Å; T90-D93 PolarHBondContact O-N 2.98Å; T90-D93 VanDerWaalsContact O-N 3.14Å; T90-D93 PolarHBondContact OG1-OD2 2.88Å; T90-T94 PolarHBondContact O-N 3.2Å
91E80.1Confident83.1Confident107 Ų10765.3 Ų65.350%0.535%0.347SS..Hα-helixtrans-59.7-34.3180-63.4-164.8-164.700112.7R29 C33 D93 T94R29-E91 IonicContact NH1-OE2 3.33Å; R29-E91 PolarHBondContact NH1-OE2 2.88Å; C33-E91 HydrophobicContact CB-CG 4.44Å; E91-D93 VanDerWaalsContact C-N 3.33Å; E91-D93 PolarHBondContact O-N 2.92Å; E91-T94 PolarHBondContact O-N 2.97Å; E91-T94 PolarHBondContact O-OG1 3.01Å
92V80.2Confident84Confident111 Ų11164.2 Ų64.267%0.67334%0.339SS*.Hα-helixtrans-66.2-38.7179.1-174.30000110.9T90 T94 L95T90-V92 PolarHBondContact O-N 3.24Å; V92-T94 PolarHBondContact O-N 2.86Å; V92-L95 PolarHBondContact O-N 3.34Å
93D80.8Confident84.7Confident46 Ų4664 Ų6425%0.24634%0.338CS..Hα-helixtrans-66.4-30.4179.1-54.5-42.8000111.6T90 E91 L95 A96 F367T90-D93 PolarHBondContact N-OD2 3.3Å; T90-D93 VanDerWaalsContact N-OD2 3.13Å; T90-D93 PolarHBondContact O-N 2.98Å; T90-D93 VanDerWaalsContact O-N 3.14Å; T90-D93 PolarHBondContact OG1-OD2 2.88Å; E91-D93 VanDerWaalsContact C-N 3.33Å; E91-D93 PolarHBondContact O-N 2.92Å; D93-L95 VanDerWaalsContact C-N 3.27Å; D93-L95 PolarHBondContact O-N 3.36Å; D93-A96 PolarHBondContact O-N 3.38Å; D93-F367 HydrophobicContact CB-CE1 4.24Å; D93-F367 HydrophobicContact CB-CZ 3.84Å
94T79.9Confident85.5Confident1 Ų158.5 Ų58.51%0.00631%0.312CS..Hα-helixtrans-67.5-26.3-179.664.90000113.9C33 I89 T90 E91 V92 A96 L97 F100C33-T94 WeakPolarHBondContact SG-CG2 3.09Å; I89-T94 HydrophobicContact CG2-CG2 3.77Å; T90-T94 PolarHBondContact O-N 3.2Å; E91-T94 PolarHBondContact O-N 2.97Å; E91-T94 PolarHBondContact O-OG1 3.01Å; V92-T94 PolarHBondContact O-N 2.86Å; T94-A96 PolarHBondContact O-N 3.42Å; T94-L97 HydrophobicContact CG2-CD1 4.14Å; T94-L97 WeakPolarHBondContact O-CB 3.42Å; T94-L97 PolarHBondContact O-N 3.11Å; T94-L97 VanDerWaalsContact O-N 3.16Å; T94-F100 HydrophobicContact CG2-CE2 4.21Å; T94-F100 WeakPolarHBondContact O-CB 3.47Å; T94-F100 VanDerWaalsContact O-CG 3.25Å; T94-F100 WeakPolarHBondContact O-CG 3.06Å
95L79.1Confident86Confident137 Ų13764.6 Ų64.672%0.71733%0.334SS*.THydrogen-bonded Turntrans-66.3-25.4177-63.7174.7000112.6V92 D93V92-L95 PolarHBondContact O-N 3.34Å; D93-L95 VanDerWaalsContact C-N 3.27Å; D93-L95 PolarHBondContact O-N 3.36Å
96A82.8Confident86.6Confident57 Ų5759.1 Ų59.147%0.47131%0.309SS..THydrogen-bonded Turntrans-86.1-9.3178.800000112.7D93 T94 Y368D93-A96 PolarHBondContact O-N 3.38Å; T94-A96 PolarHBondContact O-N 3.42Å; A96-Y368 HydrophobicContact CB-CE1 3.96Å; A96-Y368 VanDerWaalsContact O-CD1 3.24Å; A96-Y368 WeakPolarHBondContact O-CD1 3.15Å; A96-Y368 WeakPolarHBondContact O-CE1 3.47Å
97L86.7Confident87.1Confident8 Ų856.2 Ų56.24%0.04229%0.291CS..SBendtrans-73.8138.4-177.5-66.5174.1000111.8T94 F100 F367 L370 C371T94-L97 HydrophobicContact CG2-CD1 4.14Å; T94-L97 WeakPolarHBondContact O-CB 3.42Å; T94-L97 PolarHBondContact O-N 3.11Å; T94-L97 VanDerWaalsContact O-N 3.16Å; L97-F100 HydrophobicContact CB-CB 4.08Å; L97-F100 WeakPolarHBondContact O-CB 3.44Å; L97-F100 PolarHBondContact O-N 2.96Å; L97-F367 HydrophobicContact CD2-CD1 4.02Å; L97-F367 HydrophobicContact CD2-CD2 4.32Å; L97-F367 HydrophobicContact CD2-CE1 3.76Å; L97-F367 HydrophobicContact CD2-CE2 4.07Å; L97-F367 HydrophobicContact CD2-CG 4.3Å; L97-F367 HydrophobicContact CD2-CZ 3.78Å; L97-F367 WeakPolarHBondContact CD2-O 3.38Å; L97-F367 HydrophobicContact CG-CZ 4.33Å; L97-L370 HydrophobicContact CD1-CD2 4.43Å; L97-L370 HydrophobicContact CD2-CB 4.39Å; L97-C371 HydrophobicContact CB-CB 4.45Å; L97-C371 VanDerWaalsContact CD1-SG 3.57Å
98Y86Confident87.5Confident105 Ų10551.8 Ų51.841%0.41227%0.272SS..THydrogen-bonded Turntrans-71.9134.9177.3-172.1-125.9000110.6F100 H157 Y368 C371 V372Y98-F100 VanDerWaalsContact C-N 3.25Å; Y98-F100 PolarHBondContact O-N 3.43Å; Y98-H157 AromaticContact CE1-CE1 3.82Å; Y98-H157 PolarHBondContact OH-CE1 3.17Å; Y98-H157 PolarHBondContact OH-ND1 2.99Å; Y98-Y368 WeakPolarHBondContact CB-O 3.46Å; Y98-Y368 PolarHBondContact N-O 3.05Å; Y98-Y368 VanDerWaalsContact N-O 3.17Å; Y98-C371 WeakPolarHBondContact O-CB 3.21Å; Y98-V372 HydrophobicContact CD1-CG2 3.9Å; Y98-V372 HydrophobicContact CE1-CG2 4.45Å
99Y89.6Confident88Confident25 Ų2549.7 Ų49.710%0.09826%0.256CS..THydrogen-bonded Turntrans64.316.4-173.6-79.3-91.8000116.2E102 F103 S153 L154 V372 L375Y99-E102 VanDerWaalsContact C-OE2 3.3Å; Y99-E102 WeakPolarHBondContact CA-OE2 3.21Å; Y99-E102 HydrophobicContact CD1-CB 3.94Å; Y99-E102 HydrophobicContact CD1-CG 3.75Å; Y99-E102 HydrophobicContact CE1-CG 4.29Å; Y99-E102 PolarHBondContact O-N 3.37Å; Y99-F103 WeakPolarHBondContact O-CB 3.44Å; Y99-F103 PolarHBondContact O-N 3.04Å; Y99-S153 PolarHBondContact OH-OG 3.48Å; Y99-L154 HydrophobicContact CE1-CD2 4.47Å; Y99-V372 HydrophobicContact CD2-CG2 3.68Å; Y99-V372 HydrophobicContact CE2-CG2 4.45Å; Y99-V372 HydrophobicContact CG-CG2 4.22Å; Y99-L375 HydrophobicContact CD1-CD1 4.21Å; Y99-L375 HydrophobicContact CG-CD1 4.36Å
100F91.3Very high88.5Confident9 Ų950 Ų504%0.03926%0.258CS..Hα-helixtrans-59.2-44.9177.5178.1-102.1000113.8R29 L32 T94 L97 Y98 E102 F103 Q104R29-F100 HydrophobicContact CG-CE2 4.4Å; R29-F100 HydrophobicContact CG-CZ 3.75Å; L32-F100 HydrophobicContact CD1-CD2 4.5Å; L32-F100 HydrophobicContact CD1-CE2 4.38Å; T94-F100 HydrophobicContact CG2-CE2 4.21Å; T94-F100 WeakPolarHBondContact O-CB 3.47Å; T94-F100 VanDerWaalsContact O-CG 3.25Å; T94-F100 WeakPolarHBondContact O-CG 3.06Å; L97-F100 HydrophobicContact CB-CB 4.08Å; L97-F100 WeakPolarHBondContact O-CB 3.44Å; L97-F100 PolarHBondContact O-N 2.96Å; Y98-F100 VanDerWaalsContact C-N 3.25Å; Y98-F100 PolarHBondContact O-N 3.43Å; F100-E102 VanDerWaalsContact C-N 3.3Å; F100-E102 PolarHBondContact O-N 3.07Å; F100-F103 PolarHBondContact O-N 3.27Å; F100-Q104 VanDerWaalsContact CE1-OE1 3.25Å; F100-Q104 WeakPolarHBondContact O-CB 3.39Å; F100-Q104 PolarHBondContact O-N 3.29Å
101P91.8Very high89.2Confident71 Ų7150 Ų5046%0.46126%0.257SS..Hα-helixtrans-58.6-41.3177.5-24.735.1000112.8Q104 W105P101-Q104 PolarHBondContact O-N 2.91Å; P101-W105 WeakPolarHBondContact O-CB 3.16Å; P101-W105 VanDerWaalsContact O-CD1 3.24Å; P101-W105 PolarHBondContact O-N 3.27Å
102E93.1Very high89.9Confident77 Ų7745.3 Ų45.336%0.3624%0.237SC..Hα-helixtrans-67.7-40.6178.9-65.880.9176.200111.7Y99 F100 L106 L375Y99-E102 VanDerWaalsContact C-OE2 3.3Å; Y99-E102 WeakPolarHBondContact CA-OE2 3.21Å; Y99-E102 HydrophobicContact CD1-CB 3.94Å; Y99-E102 HydrophobicContact CD1-CG 3.75Å; Y99-E102 HydrophobicContact CE1-CG 4.29Å; Y99-E102 PolarHBondContact O-N 3.37Å; F100-E102 VanDerWaalsContact C-N 3.3Å; F100-E102 PolarHBondContact O-N 3.07Å; E102-L106 WeakPolarHBondContact O-CB 3.14Å; E102-L106 PolarHBondContact O-N 2.7Å; E102-L375 HydrophobicContact CB-CD1 4.25Å
103F93.4Very high90.6Very high0 Ų040 Ų400%021%0.205CC..Hα-helixtrans-61.7-47.9173.2175.4-104.5000111.7A28 L31 L32 Y99 F100 L106 V107 M329 C371 A374 L375 V378A28-F103 HydrophobicContact CB-CD1 4.04Å; A28-F103 HydrophobicContact CB-CE1 3.78Å; L31-F103 HydrophobicContact CD2-CZ 4.23Å; L32-F103 HydrophobicContact CD1-CD1 3.88Å; L32-F103 HydrophobicContact CD1-CE1 3.48Å; L32-F103 VanDerWaalsContact CD1-CE1 3.48Å; L32-F103 HydrophobicContact CD1-CZ 4.28Å; L32-F103 HydrophobicContact CD2-CE1 4.38Å; L32-F103 HydrophobicContact CD2-CZ 4.43Å; L32-F103 HydrophobicContact CG-CE1 3.74Å; L32-F103 HydrophobicContact CG-CZ 4.21Å; Y99-F103 WeakPolarHBondContact O-CB 3.44Å; Y99-F103 PolarHBondContact O-N 3.04Å; F100-F103 PolarHBondContact O-N 3.27Å; F103-L106 PolarHBondContact O-N 3Å; F103-V107 HydrophobicContact CD2-CG2 4.14Å; F103-V107 HydrophobicContact CE1-CG2 4.48Å; F103-V107 HydrophobicContact CE2-CG2 3.71Å; F103-V107 HydrophobicContact CZ-CG2 3.91Å; F103-V107 WeakPolarHBondContact O-CG2 3.37Å; F103-V107 PolarHBondContact O-N 3.47Å; F103-V107 VanDerWaalsContact O-N 3.11Å; F103-M329 HydrophobicContact CE2-CE 4.11Å; F103-M329 HydrophobicContact CZ-CE 4.15Å; F103-C371 HydrophobicContact CB-CB 4.41Å; F103-A374 HydrophobicContact CD2-CB 3.83Å; F103-A374 HydrophobicContact CE2-CB 3.48Å; F103-A374 VanDerWaalsContact CE2-CB 3.48Å; F103-A374 HydrophobicContact CZ-CB 4.02Å; F103-L375 HydrophobicContact CB-CD1 4.35Å; F103-L375 HydrophobicContact CB-CD2 4.04Å; F103-L375 HydrophobicContact CB-CG 3.94Å; F103-L375 HydrophobicContact CD2-CD2 4.05Å; F103-L375 HydrophobicContact CD2-CG 4.07Å; F103-V378 HydrophobicContact CE2-CG2 4.34Å
104Q93.3Very high91.3Very high39 Ų3939.3 Ų39.318%0.18220%0.202CC..Hα-helixtrans-59.1-51.7178.7-177.3174.9-14.800111.2S26 A28 F100 P101 L106 V107 D108S26-Q104 WeakPolarHBondContact OG-CG 3.14Å; A28-Q104 HydrophobicContact CB-CB 4.17Å; A28-Q104 HydrophobicContact CB-CG 4.15Å; F100-Q104 VanDerWaalsContact CE1-OE1 3.25Å; F100-Q104 WeakPolarHBondContact O-CB 3.39Å; F100-Q104 PolarHBondContact O-N 3.29Å; P101-Q104 PolarHBondContact O-N 2.91Å; Q104-L106 PolarHBondContact O-N 3.49Å; Q104-V107 PolarHBondContact O-N 2.87Å; Q104-D108 VanDerWaalsContact CG-OD2 3.26Å; Q104-D108 WeakPolarHBondContact CG-OD2 3.48Å; Q104-D108 VanDerWaalsContact O-CB 3.26Å; Q104-D108 WeakPolarHBondContact O-CB 3.41Å; Q104-D108 VanDerWaalsContact O-CG 3.3Å; Q104-D108 PolarHBondContact O-N 2.88Å
105W93.1Very high92Very high144 Ų14440.8 Ų40.855%0.54521%0.214SC..Hα-helixtrans-60.5-44.8179.1-89.9107.4000112.7I18 L22 P101 F109I18-W105 HydrophobicContact CG2-CH2 4.08Å; I18-W105 HydrophobicContact CG2-CZ3 3.97Å; L22-W105 HydrophobicContact CD2-CZ3 4.43Å; P101-W105 WeakPolarHBondContact O-CB 3.16Å; P101-W105 VanDerWaalsContact O-CD1 3.24Å; P101-W105 PolarHBondContact O-N 3.27Å; W105-F109 WeakPolarHBondContact O-CB 3.48Å; W105-F109 PolarHBondContact O-N 3.46Å
106L95.1Very high92.8Very high4 Ų434.3 Ų34.32%0.02118%0.18CC..Hα-helixtrans-59.7-52.1-179.8177.760.2000111.3E102 F103 Q104 T110 V147 I150 L375 V378 A379 V382E102-L106 WeakPolarHBondContact O-CB 3.14Å; E102-L106 PolarHBondContact O-N 2.7Å; F103-L106 PolarHBondContact O-N 3Å; Q104-L106 PolarHBondContact O-N 3.49Å; L106-T110 WeakPolarHBondContact O-CB 3.45Å; L106-T110 PolarHBondContact O-N 3.19Å; L106-T110 PolarHBondContact O-OG1 3.43Å; L106-V147 HydrophobicContact CD1-CG2 3.69Å; L106-I150 HydrophobicContact CB-CD1 3.62Å; L106-I150 HydrophobicContact CD1-CD1 4.02Å; L106-I150 HydrophobicContact CD2-CD1 3.85Å; L106-I150 HydrophobicContact CG-CD1 4.01Å; L106-L375 HydrophobicContact CB-CD2 4.25Å; L106-L375 HydrophobicContact CD2-CD2 3.61Å; L106-V378 HydrophobicContact CD2-CG1 4.4Å; L106-A379 HydrophobicContact CD2-CB 4.09Å; L106-V382 HydrophobicContact CD1-CG1 4.42Å
107V95.3Very high93.4Very high8 Ų831.7 Ų31.75%0.04816%0.158CC..Hα-helixtrans-66.1-50-175.5169.90000110.7F27 A28 F103 Q104 T110 V111 V378F27-V107 HydrophobicContact CB-CG1 4.37Å; F27-V107 HydrophobicContact CD1-CG1 3.56Å; F27-V107 HydrophobicContact CE1-CG1 4.39Å; F27-V107 HydrophobicContact CG-CG1 4.44Å; A28-V107 HydrophobicContact CB-CB 3.82Å; A28-V107 HydrophobicContact CB-CG1 3.92Å; A28-V107 HydrophobicContact CB-CG2 4.39Å; F103-V107 HydrophobicContact CD2-CG2 4.14Å; F103-V107 HydrophobicContact CE1-CG2 4.48Å; F103-V107 HydrophobicContact CE2-CG2 3.71Å; F103-V107 HydrophobicContact CZ-CG2 3.91Å; F103-V107 WeakPolarHBondContact O-CG2 3.37Å; F103-V107 PolarHBondContact O-N 3.47Å; F103-V107 VanDerWaalsContact O-N 3.11Å; Q104-V107 PolarHBondContact O-N 2.87Å; V107-T110 WeakPolarHBondContact O-CB 3.3Å; V107-T110 PolarHBondContact O-N 3.44Å; V107-V111 WeakPolarHBondContact O-CG2 3.32Å; V107-V111 PolarHBondContact O-N 2.85Å; V107-V378 HydrophobicContact CG2-CG1 4.09Å
108D94.3Very high93.7Very high3 Ų336.5 Ų36.52%0.01618%0.183CC..Hα-helixtrans-69.1-40.5-174.8-69.2-19.2000111.8L22 S26 F27 A28 Q104 T110 V111 A112L22-D108 HydrophobicContact CD1-CB 3.72Å; L22-D108 HydrophobicContact CD2-CB 3.63Å; L22-D108 HydrophobicContact CG-CB 3.74Å; S26-D108 WeakPolarHBondContact CB-OD2 3.29Å; S26-D108 VanDerWaalsContact OG-CG 3.28Å; S26-D108 PolarHBondContact OG-OD1 2.88Å; S26-D108 PolarHBondContact OG-OD2 3.47Å; F27-D108 WeakPolarHBondContact CA-OD1 3.42Å; F27-D108 WeakPolarHBondContact CB-OD1 3.49Å; F27-D108 PolarHBondContact N-OD1 3.1Å; A28-D108 PolarHBondContact N-OD1 2.87Å; Q104-D108 VanDerWaalsContact CG-OD2 3.26Å; Q104-D108 WeakPolarHBondContact CG-OD2 3.48Å; Q104-D108 VanDerWaalsContact O-CB 3.26Å; Q104-D108 WeakPolarHBondContact O-CB 3.41Å; Q104-D108 VanDerWaalsContact O-CG 3.3Å; Q104-D108 PolarHBondContact O-N 2.88Å; D108-T110 VanDerWaalsContact C-N 3.33Å; D108-T110 PolarHBondContact O-N 3.27Å; D108-V111 PolarHBondContact O-N 3.38Å; D108-A112 PolarHBondContact O-N 2.93Å
109F95.3Very high94Very high18 Ų1835.2 Ų35.28%0.07918%0.183CC..Hα-helixtrans-65.9-36.8174.8-174.2-101.3000111.9I18 W105 A112 A113 W139 L142 V143 F146I18-F109 HydrophobicContact CD1-CD2 4.14Å; I18-F109 HydrophobicContact CD1-CE2 4.37Å; W105-F109 WeakPolarHBondContact O-CB 3.48Å; W105-F109 PolarHBondContact O-N 3.46Å; F109-A112 PolarHBondContact O-N 2.89Å; F109-A113 VanDerWaalsContact O-CB 3.29Å; F109-A113 WeakPolarHBondContact O-CB 3.37Å; F109-A113 PolarHBondContact O-N 3.33Å; F109-W139 HydrophobicContact CD2-CZ3 4.3Å; F109-W139 AromaticContact CE2-CE3 3.92Å; F109-W139 HydrophobicContact CE2-CE3 3.92Å; F109-W139 AromaticContact CE2-CZ3 3.55Å; F109-W139 HydrophobicContact CE2-CZ3 3.55Å; F109-W139 AromaticContact CZ-CE3 3.83Å; F109-W139 HydrophobicContact CZ-CE3 3.83Å; F109-W139 AromaticContact CZ-CZ3 3.96Å; F109-W139 HydrophobicContact CZ-CZ3 3.96Å; F109-L142 HydrophobicContact CE1-CB 4.01Å; F109-L142 HydrophobicContact CZ-CB 4Å; F109-L142 HydrophobicContact CZ-CD1 4.38Å; F109-V143 HydrophobicContact CD1-CG2 3.66Å; F109-V143 HydrophobicContact CE1-CB 4.46Å; F109-V143 HydrophobicContact CE1-CG2 3.55Å; F109-F146 AromaticContact CD1-CD2 3.44Å; F109-F146 HydrophobicContact CD1-CD2 3.44Å; F109-F146 VanDerWaalsContact CD1-CD2 3.44Å; F109-F146 AromaticContact CD1-CE2 3.56Å; F109-F146 HydrophobicContact CD1-CE2 3.56Å; F109-F146 HydrophobicContact CD2-CE2 4.18Å; F109-F146 AromaticContact CE1-CD2 3.59Å; F109-F146 HydrophobicContact CE1-CD2 3.59Å; F109-F146 AromaticContact CE1-CE2 3.49Å; F109-F146 HydrophobicContact CE1-CE2 3.49Å; F109-F146 VanDerWaalsContact CE1-CE2 3.49Å; F109-F146 HydrophobicContact CE2-CE2 4.13Å; F109-F146 HydrophobicContact CG-CD2 4.1Å; F109-F146 AromaticContact CG-CE2 3.9Å; F109-F146 HydrophobicContact CG-CE2 3.9Å; F109-F146 HydrophobicContact CZ-CD2 4.35Å; F109-F146 AromaticContact CZ-CE2 3.8Å; F109-F146 HydrophobicContact CZ-CE2 3.8Å
110T96Very high94Very high12 Ų1234.2 Ų34.27%0.07418%0.179CC..Hα-helixtrans-61.4-45.2174.4-640000111.4L106 V107 D108 A113 T114 V382 H386L106-T110 WeakPolarHBondContact O-CB 3.45Å; L106-T110 PolarHBondContact O-N 3.19Å; L106-T110 PolarHBondContact O-OG1 3.43Å; V107-T110 WeakPolarHBondContact O-CB 3.3Å; V107-T110 PolarHBondContact O-N 3.44Å; D108-T110 VanDerWaalsContact C-N 3.33Å; D108-T110 PolarHBondContact O-N 3.27Å; T110-A113 PolarHBondContact O-N 3.49Å; T110-T114 WeakPolarHBondContact O-CB 3.15Å; T110-T114 PolarHBondContact O-N 2.84Å; T110-T114 PolarHBondContact O-OG1 3.33Å; T110-V382 HydrophobicContact CG2-CB 4.38Å; T110-V382 HydrophobicContact CG2-CG1 3.75Å; T110-V382 HydrophobicContact CG2-CG2 3.8Å; T110-V382 WeakPolarHBondContact OG1-CG1 3.4Å; T110-H386 VanDerWaalsContact CG2-CE1 3.49Å; T110-H386 WeakPolarHBondContact CG2-CE1 3.37Å
111V95.3Very high93.9Very high68 Ų6834.9 Ų34.941%0.41218%0.183SC..Hα-helixtrans-62.4-45.2177.5172.10000110.4F27 V107 D108 T114 A115F27-V111 HydrophobicContact CB-CG2 4.32Å; F27-V111 HydrophobicContact CD1-CG2 3.82Å; F27-V111 HydrophobicContact CE1-CG2 4.36Å; F27-V111 HydrophobicContact CG-CG2 4.1Å; V107-V111 WeakPolarHBondContact O-CG2 3.32Å; V107-V111 PolarHBondContact O-N 2.85Å; D108-V111 PolarHBondContact O-N 3.38Å; V111-T114 PolarHBondContact O-N 3.37Å; V111-A115 WeakPolarHBondContact O-CB 3.36Å; V111-A115 PolarHBondContact O-N 2.96Å
112A94.9Very high93.8Very high8 Ų837.2 Ų37.27%0.06619%0.191CC..Hα-helixtrans-60.8-47.5176.600000112.3M14 I18 D108 F109 T114 A115 V116M14-A112 HydrophobicContact CG-CB 4.02Å; M14-A112 HydrophobicContact SD-CB 3.73Å; I18-A112 HydrophobicContact CD1-CB 3.9Å; I18-A112 HydrophobicContact CG1-CB 4.03Å; D108-A112 PolarHBondContact O-N 2.93Å; F109-A112 PolarHBondContact O-N 2.89Å; A112-T114 PolarHBondContact O-N 3.01Å; A112-A115 PolarHBondContact O-N 3.24Å; A112-V116 WeakPolarHBondContact O-CG2 3.48Å; A112-V116 PolarHBondContact O-N 3.23Å
113A96.2Very high93.5Very high0 Ų036 Ų360%018%0.183CC..Hα-helixtrans-63.6-41178.200000112.3F109 T110 A115 V116 Y117 W139 V143F109-A113 VanDerWaalsContact O-CB 3.29Å; F109-A113 WeakPolarHBondContact O-CB 3.37Å; F109-A113 PolarHBondContact O-N 3.33Å; T110-A113 PolarHBondContact O-N 3.49Å; A113-A115 VanDerWaalsContact C-N 3.34Å; A113-V116 PolarHBondContact O-N 2.95Å; A113-Y117 WeakPolarHBondContact O-CB 3.42Å; A113-Y117 PolarHBondContact O-N 3.3Å; A113-W139 HydrophobicContact CB-CB 4.2Å; A113-W139 HydrophobicContact CB-CE3 4.01Å; A113-V143 HydrophobicContact CB-CG2 3.35Å
114T95.6Very high93.1Very high31 Ų3138.5 Ų38.519%0.1919%0.193CC..Hα-helixtrans-64.3-40.7175.4-53.90000110.6T110 V111 A112 Y117 L118 H386T110-T114 WeakPolarHBondContact O-CB 3.15Å; T110-T114 PolarHBondContact O-N 2.84Å; T110-T114 PolarHBondContact O-OG1 3.33Å; V111-T114 PolarHBondContact O-N 3.37Å; A112-T114 PolarHBondContact O-N 3.01Å; T114-Y117 WeakPolarHBondContact O-CB 3.41Å; T114-Y117 PolarHBondContact O-N 2.99Å; T114-L118 HydrophobicContact CG2-CD1 4.31Å; T114-L118 HydrophobicContact CG2-CG 4.49Å; T114-L118 VanDerWaalsContact O-CG 3.3Å; T114-L118 WeakPolarHBondContact O-CG 3.42Å; T114-L118 PolarHBondContact O-N 2.95Å; T114-H386 PolarHBondContact OG1-CE1 2.79Å
115A95.1Very high92.6Very high32 Ų3239.2 Ų39.226%0.26421%0.211SC..Hα-helixtrans-64.1-44.1175.100000112.1M14 V111 A112 A113 Y117 L118 I119M14-A115 HydrophobicContact CE-CB 3.85Å; V111-A115 WeakPolarHBondContact O-CB 3.36Å; V111-A115 PolarHBondContact O-N 2.96Å; A112-A115 PolarHBondContact O-N 3.24Å; A113-A115 VanDerWaalsContact C-N 3.34Å; A115-Y117 VanDerWaalsContact C-N 3.28Å; A115-Y117 PolarHBondContact O-N 3.49Å; A115-L118 PolarHBondContact O-N 3.46Å; A115-I119 WeakPolarHBondContact O-CB 3.49Å; A115-I119 VanDerWaalsContact O-CG1 3.26Å; A115-I119 WeakPolarHBondContact O-CG1 3.48Å; A115-I119 PolarHBondContact O-N 3.46Å
116V94.9Very high92.2Very high1 Ų138 Ų381%0.00622%0.219CC..Hα-helixtrans-57.6-44.9173.4170.90000110.4V10 M14 A112 A113 I119 T120 W139V10-V116 HydrophobicContact CG1-CG1 4.28Å; V10-V116 HydrophobicContact CG1-CG2 4.43Å; M14-V116 HydrophobicContact CB-CG2 3.62Å; M14-V116 HydrophobicContact CE-CG2 3.86Å; M14-V116 HydrophobicContact CG-CG2 3.52Å; A112-V116 WeakPolarHBondContact O-CG2 3.48Å; A112-V116 PolarHBondContact O-N 3.23Å; A113-V116 PolarHBondContact O-N 2.95Å; V116-I119 PolarHBondContact O-N 3.42Å; V116-T120 VanDerWaalsContact O-CB 3.28Å; V116-T120 WeakPolarHBondContact O-CB 3.26Å; V116-T120 PolarHBondContact O-N 2.91Å; V116-T120 PolarHBondContact O-OG1 2.91Å; V116-W139 HydrophobicContact CB-CG 4.5Å; V116-W139 HydrophobicContact CG1-CD2 4.42Å; V116-W139 HydrophobicContact CG1-CG 4.11Å; V116-W139 HydrophobicContact CG2-CD2 4.31Å; V116-W139 HydrophobicContact CG2-CZ2 4.29Å
117Y94.4Very high91.4Very high2 Ų240.4 Ų40.41%0.00824%0.239CC..Hα-helixtrans-59.6-49.7177-177.2-85.7000111.9A113 T114 A115 I119 T120 E121 S136 L389 K392 T393 W399A113-Y117 WeakPolarHBondContact O-CB 3.42Å; A113-Y117 PolarHBondContact O-N 3.3Å; T114-Y117 WeakPolarHBondContact O-CB 3.41Å; T114-Y117 PolarHBondContact O-N 2.99Å; A115-Y117 VanDerWaalsContact C-N 3.28Å; A115-Y117 PolarHBondContact O-N 3.49Å; Y117-I119 PolarHBondContact O-N 2.96Å; Y117-T120 PolarHBondContact O-N 3.42Å; Y117-E121 HydrophobicContact CD1-CG 3.81Å; Y117-E121 HydrophobicContact CE1-CG 3.43Å; Y117-E121 VanDerWaalsContact CE1-CG 3.43Å; Y117-E121 HydrophobicContact CG-CG 4.5Å; Y117-E121 WeakPolarHBondContact O-CB 3.47Å; Y117-E121 VanDerWaalsContact O-CG 3.27Å; Y117-E121 WeakPolarHBondContact O-CG 3.48Å; Y117-E121 PolarHBondContact O-N 3.37Å; Y117-S136 WeakPolarHBondContact CD2-OG 3.46Å; Y117-L389 HydrophobicContact CD1-CD1 3.94Å; Y117-L389 HydrophobicContact CD1-CD2 4.07Å; Y117-L389 HydrophobicContact CD1-CG 4.41Å; Y117-L389 HydrophobicContact CD2-CB 4.26Å; Y117-L389 HydrophobicContact CD2-CD1 4.36Å; Y117-L389 HydrophobicContact CE1-CB 4.19Å; Y117-L389 HydrophobicContact CE1-CD1 4.25Å; Y117-L389 HydrophobicContact CE1-CD2 3.62Å; Y117-L389 HydrophobicContact CE1-CG 4.21Å; Y117-L389 HydrophobicContact CE2-CB 3.81Å; Y117-L389 HydrophobicContact CG-CD1 4Å; Y117-L389 PolarHBondContact OH-O 2.99Å; Y117-L389 VanDerWaalsContact OH-O 3.09Å; Y117-K392 WeakPolarHBondContact OH-CD 3.02Å; Y117-T393 VanDerWaalsContact CE2-OG1 3.23Å; Y117-T393 WeakPolarHBondContact CE2-OG1 3.23Å; Y117-T393 PolarHBondContact OH-OG1 3.19Å; Y117-W399 HydrophobicContact CE1-CZ2 4.35Å
118L93.5Very high90.5Very high109 Ų10947.7 Ų47.757%0.57127%0.273SS*.Hα-helixtrans-62.6-41.8179.7-68.8174.7000112.9T114 A115 T120 E121 L122T114-L118 HydrophobicContact CG2-CD1 4.31Å; T114-L118 HydrophobicContact CG2-CG 4.49Å; T114-L118 VanDerWaalsContact O-CG 3.3Å; T114-L118 WeakPolarHBondContact O-CG 3.42Å; T114-L118 PolarHBondContact O-N 2.95Å; A115-L118 PolarHBondContact O-N 3.46Å; L118-T120 VanDerWaalsContact C-N 3.32Å; L118-E121 PolarHBondContact O-N 3.11Å; L118-L122 WeakPolarHBondContact O-CB 3.36Å; L118-L122 PolarHBondContact O-N 3.44Å
119I92.5Very high89.4Confident79 Ų7948.9 Ų48.941%0.40528%0.28SS..Hα-helixtrans-64-41.8175.7-67.2164.9000110.2V10 A115 V116 Y117 L122 Y123V10-I119 HydrophobicContact CG1-CB 4.44Å; V10-I119 HydrophobicContact CG1-CG2 4.02Å; V10-I119 HydrophobicContact CG2-CG2 3.96Å; A115-I119 WeakPolarHBondContact O-CB 3.49Å; A115-I119 VanDerWaalsContact O-CG1 3.26Å; A115-I119 WeakPolarHBondContact O-CG1 3.48Å; A115-I119 PolarHBondContact O-N 3.46Å; V116-I119 PolarHBondContact O-N 3.42Å; Y117-I119 PolarHBondContact O-N 2.96Å; I119-L122 PolarHBondContact O-N 3.27Å; I119-Y123 WeakPolarHBondContact O-CB 3.46Å; I119-Y123 PolarHBondContact O-N 3.49Å
120T90.6Very high87.7Confident3 Ų353.1 Ų53.12%0.01831%0.312CS..Hα-helixtrans-66.2-41.6179.1-55.40000110.8Q7 V116 Y117 L118 Y123 Y124 N134Q7-T120 HydrophobicContact CG-CG2 4.4Å; V116-T120 VanDerWaalsContact O-CB 3.28Å; V116-T120 WeakPolarHBondContact O-CB 3.26Å; V116-T120 PolarHBondContact O-N 2.91Å; V116-T120 PolarHBondContact O-OG1 2.91Å; Y117-T120 PolarHBondContact O-N 3.42Å; L118-T120 VanDerWaalsContact C-N 3.32Å; T120-Y123 WeakPolarHBondContact O-CB 3.42Å; T120-Y123 PolarHBondContact O-N 3.3Å; T120-Y124 HydrophobicContact CG2-CD2 3.75Å; T120-Y124 HydrophobicContact CG2-CE2 3.6Å; T120-Y124 VanDerWaalsContact O-CD2 3.24Å; T120-Y124 WeakPolarHBondContact O-CD2 3.22Å; T120-Y124 PolarHBondContact O-N 3.28Å; T120-N134 VanDerWaalsContact CG2-OD1 3.23Å; T120-N134 WeakPolarHBondContact CG2-OD1 3.48Å
121E89.1Confident86.2Confident24 Ų2455.4 Ų55.411%0.11234%0.339CS..Hα-helixtrans-61.3-43.9174.2-77.1-77.4121.900112.6Y117 L118 Y123 Y124 G125 K392 W399Y117-E121 HydrophobicContact CD1-CG 3.81Å; Y117-E121 HydrophobicContact CE1-CG 3.43Å; Y117-E121 VanDerWaalsContact CE1-CG 3.43Å; Y117-E121 HydrophobicContact CG-CG 4.5Å; Y117-E121 WeakPolarHBondContact O-CB 3.47Å; Y117-E121 VanDerWaalsContact O-CG 3.27Å; Y117-E121 WeakPolarHBondContact O-CG 3.48Å; Y117-E121 PolarHBondContact O-N 3.37Å; L118-E121 PolarHBondContact O-N 3.11Å; E121-Y123 VanDerWaalsContact C-N 3.3Å; E121-Y123 PolarHBondContact O-N 3.18Å; E121-Y124 PolarHBondContact O-N 3.16Å; E121-G125 PolarHBondContact O-N 3.34Å; E121-K392 IonicContact OE1-NZ 3.77Å; E121-K392 PolarHBondContact OE1-NZ 2.87Å; E121-K392 WeakPolarHBondContact OE2-CE 3.02Å; E121-K392 IonicContact OE2-NZ 2.62Å; E121-K392 PolarHBondContact OE2-NZ 3.01Å; E121-W399 VanDerWaalsContact OE2-CD1 3.28Å; E121-W399 PolarHBondContact OE2-NE1 3.21Å
122L89Confident85.3Confident120 Ų12054 Ų5463%0.62833%0.327SS*.Hα-helixtrans-61.4-41.6174.5-178.463.1000111.2L118 I119 G125 V126L118-L122 WeakPolarHBondContact O-CB 3.36Å; L118-L122 PolarHBondContact O-N 3.44Å; I119-L122 PolarHBondContact O-N 3.27Å; L122-G125 PolarHBondContact O-N 2.87Å; L122-V126 HydrophobicContact CD1-CG2 4.22Å; L122-V126 WeakPolarHBondContact O-CG2 3.37Å; L122-V126 PolarHBondContact O-N 3.15Å
123Y87.8Confident84.3Confident50 Ų5057.9 Ų57.920%0.19635%0.346CS..Hα-helixtrans-61.8-46.6175.7170.5-114.1000112.1V6 Q7 I119 T120 E121 G125 V126 A127 P129 E132V6-Y123 HydrophobicContact CB-CE1 4.19Å; V6-Y123 HydrophobicContact CB-CE2 4Å; V6-Y123 HydrophobicContact CG1-CD2 4.07Å; V6-Y123 HydrophobicContact CG1-CE1 4.47Å; V6-Y123 HydrophobicContact CG1-CE2 3.93Å; V6-Y123 HydrophobicContact CG1-CG 4.42Å; V6-Y123 HydrophobicContact CG2-CE2 3.96Å; Q7-Y123 HydrophobicContact CG-CD1 4.41Å; Q7-Y123 HydrophobicContact CG-CE1 4.28Å; I119-Y123 WeakPolarHBondContact O-CB 3.46Å; I119-Y123 PolarHBondContact O-N 3.49Å; T120-Y123 WeakPolarHBondContact O-CB 3.42Å; T120-Y123 PolarHBondContact O-N 3.3Å; E121-Y123 VanDerWaalsContact C-N 3.3Å; E121-Y123 PolarHBondContact O-N 3.18Å; Y123-G125 VanDerWaalsContact C-N 3.3Å; Y123-G125 PolarHBondContact O-N 3.4Å; Y123-V126 PolarHBondContact O-N 2.89Å; Y123-A127 HydrophobicContact CD2-CB 3.82Å; Y123-A127 HydrophobicContact CE2-CB 3.58Å; Y123-A127 WeakPolarHBondContact O-CB 3.43Å; Y123-A127 PolarHBondContact O-N 3.35Å; Y123-P129 HydrophobicContact CD1-CG 4.33Å; Y123-P129 HydrophobicContact CE1-CB 4.35Å; Y123-P129 HydrophobicContact CE1-CG 3.65Å; Y123-E132 PolarHBondContact OH-OE2 2.95Å
124Y84.2Confident83.8Confident54 Ų5459 Ų5921%0.21235%0.351CS..Hα-helixtrans-63.3-36.2175.1-85.1-77.6000112.5Q7 T120 E121 Q128 P129 E132 N134Q7-Y124 PolarHBondContact NE2-OH 3.33Å; T120-Y124 HydrophobicContact CG2-CD2 3.75Å; T120-Y124 HydrophobicContact CG2-CE2 3.6Å; T120-Y124 VanDerWaalsContact O-CD2 3.24Å; T120-Y124 WeakPolarHBondContact O-CD2 3.22Å; T120-Y124 PolarHBondContact O-N 3.28Å; E121-Y124 PolarHBondContact O-N 3.16Å; Y124-Q128 PolarHBondContact O-N 3.1Å; Y124-P129 HydrophobicContact CD1-CG 3.75Å; Y124-P129 HydrophobicContact CE1-CG 3.71Å; Y124-E132 PolarHBondContact OH-O 3.49Å; Y124-N134 HydrophobicContact CE2-CB 4.1Å
125G82.6Confident83.5Confident54 Ų5458.6 Ų58.656%0.55735%0.348SS*.Hα-helixtrans-67-33.8177.400000114E121 L122 Y123E121-G125 PolarHBondContact O-N 3.34Å; L122-G125 PolarHBondContact O-N 2.87Å; Y123-G125 VanDerWaalsContact C-N 3.3Å; Y123-G125 PolarHBondContact O-N 3.4Å
126V84.6Confident83.3Confident119 Ų11957 Ų5772%0.72134%0.335SS*.Hα-helixtrans-94.4-43.1-177176.50000112.8L122 Y123L122-V126 HydrophobicContact CD1-CG2 4.22Å; L122-V126 WeakPolarHBondContact O-CG2 3.37Å; L122-V126 PolarHBondContact O-N 3.15Å; Y123-V126 PolarHBondContact O-N 2.89Å
127A78.8Confident83.1Confident53 Ų5358 Ų5844%0.43834%0.341SS..Hα-helixtrans-99.3-12.5-168.500000114.5Y123 P129Y123-A127 HydrophobicContact CD2-CB 3.82Å; Y123-A127 HydrophobicContact CE2-CB 3.58Å; Y123-A127 WeakPolarHBondContact O-CB 3.43Å; Y123-A127 PolarHBondContact O-N 3.35Å; A127-P129 VanDerWaalsContact C-CD 3.44Å; A127-P129 VanDerWaalsContact C-N 3.34Å
128Q75.8Confident83.1Confident162 Ų16261.1 Ų61.176%0.75736%0.36SS*.  trans37.553.5-177.2-63.5-171.2-16.500114.6Y124 S130Y124-Q128 PolarHBondContact O-N 3.1Å; Q128-S130 PolarHBondContact O-N 3.3Å
129P71.1Confident83.2Confident27 Ų2756.9 Ų56.918%0.17534%0.336CS..  trans-68.6125.9-175.829.5-35.4000111.1Y123 Y124 A127 E132Y123-P129 HydrophobicContact CD1-CG 4.33Å; Y123-P129 HydrophobicContact CE1-CB 4.35Å; Y123-P129 HydrophobicContact CE1-CG 3.65Å; Y124-P129 HydrophobicContact CD1-CG 3.75Å; Y124-P129 HydrophobicContact CE1-CG 3.71Å; A127-P129 VanDerWaalsContact C-CD 3.44Å; A127-P129 VanDerWaalsContact C-N 3.34Å; P129-E132 HydrophobicContact CB-CG 4.46Å
130S60.4Low83.3Confident107 Ų10753.1 Ų53.175%0.74832%0.317SS*.SBendtrans-90.4122.2174.5540000110.9Q128Q128-S130 PolarHBondContact O-N 3.3Å
131G65.1Low83.6Confident61 Ų6156.9 Ų56.963%0.62934%0.337SS*.SBendtrans96.40.917000000117.6
132E74.8Confident83.9Confident37 Ų3759.5 Ų59.517%0.17335%0.351CS..  trans-83.5137.1173.2-65.1-173.8170.400111.7Y123 Y124 P129Y123-E132 PolarHBondContact OH-OE2 2.95Å; Y124-E132 PolarHBondContact OH-O 3.49Å; P129-E132 HydrophobicContact CB-CG 4.46Å
133M75.2Confident84.3Confident91 Ų9153.8 Ų53.845%0.44832%0.321SS..  trans-77.6126173.9-177.7176.582.700109.7F4 Q7 I135F4-M133 HydrophobicContact CE1-CB 3.93Å; F4-M133 HydrophobicContact CE1-CE 3.66Å; F4-M133 HydrophobicContact CZ-CE 3.88Å; Q7-M133 PolarHBondContact OE1-O 3.23Å; M133-I135 PolarHBondContact O-N 2.86Å
134N85.8Confident84.7Confident23 Ų2352.4 Ų52.412%0.12332%0.317CS..  trans-68.8101.1-177.4-168.9-11000112.1T120 Y124 S136 V137 T393T120-N134 VanDerWaalsContact CG2-OD1 3.23Å; T120-N134 WeakPolarHBondContact CG2-OD1 3.48Å; Y124-N134 HydrophobicContact CE2-CB 4.1Å; N134-S136 PolarHBondContact ND2-OG 3.32Å; N134-S136 PolarHBondContact O-N 2.95Å; N134-S136 WeakPolarHBondContact OD1-CB 3.41Å; N134-S136 PolarHBondContact OD1-N 3.11Å; N134-S136 PolarHBondContact OD1-OG 2.96Å; N134-V137 HydrophobicContact CB-CG2 4.13Å; N134-V137 WeakPolarHBondContact O-CB 3.38Å; N134-V137 PolarHBondContact O-N 3.23Å; N134-T393 VanDerWaalsContact ND2-CG2 3.32Å; N134-T393 WeakPolarHBondContact ND2-CG2 3.34Å
135I88.5Confident85.3Confident22 Ų2252.4 Ų52.411%0.11333%0.328CS..Hα-helixtrans-64-25.3179.5-58.7179.6000111.5F4 Q7 L8 T11 M133 V137 V138 W139F4-I135 HydrophobicContact CB-CD1 4.26Å; F4-I135 HydrophobicContact CD1-CD1 3.68Å; F4-I135 HydrophobicContact CD1-CG1 3.81Å; F4-I135 HydrophobicContact CE1-CD1 4.47Å; F4-I135 HydrophobicContact CE1-CG1 4.22Å; F4-I135 HydrophobicContact CG-CD1 4.35Å; Q7-I135 HydrophobicContact CB-CB 4.21Å; Q7-I135 HydrophobicContact CB-CD1 3.56Å; Q7-I135 HydrophobicContact CB-CG1 3.91Å; L8-I135 HydrophobicContact CB-CD1 4.32Å; T11-I135 WeakPolarHBondContact OG1-CG2 3.3Å; M133-I135 PolarHBondContact O-N 2.86Å; I135-V137 PolarHBondContact O-N 3.27Å; I135-V138 WeakPolarHBondContact O-CB 3.11Å; I135-V138 PolarHBondContact O-N 3.25Å; I135-W139 PolarHBondContact O-N 2.9Å
136S90.4Very high85.9Confident0 Ų053.7 Ų53.70%032%0.319CS..Hα-helixtrans-62.9-28.1179.879.80000112.8Y117 N134 V138 W139 C140Y117-S136 WeakPolarHBondContact CD2-OG 3.46Å; N134-S136 PolarHBondContact ND2-OG 3.32Å; N134-S136 PolarHBondContact O-N 2.95Å; N134-S136 WeakPolarHBondContact OD1-CB 3.41Å; N134-S136 PolarHBondContact OD1-N 3.11Å; N134-S136 PolarHBondContact OD1-OG 2.96Å; S136-V138 VanDerWaalsContact C-N 3.29Å; S136-V138 PolarHBondContact O-N 3.03Å; S136-W139 WeakPolarHBondContact O-CB 3.45Å; S136-W139 PolarHBondContact O-N 3Å; S136-C140 PolarHBondContact O-N 3.48Å; S136-C140 PolarHBondContact O-SG 2.89Å; S136-C140 VanDerWaalsContact O-SG 3.33Å
137V92.1Very high86.5Confident21 Ų2148 Ų4813%0.12728%0.284CS..Hα-helixtrans-58.8-42.4172.5174.70000110.7N134 I135 C140 L141 L390 T393 L394N134-V137 HydrophobicContact CB-CG2 4.13Å; N134-V137 WeakPolarHBondContact O-CB 3.38Å; N134-V137 PolarHBondContact O-N 3.23Å; I135-V137 PolarHBondContact O-N 3.27Å; V137-C140 PolarHBondContact O-N 3.02Å; V137-L141 HydrophobicContact CG1-CD1 4.12Å; V137-L141 HydrophobicContact CG1-CG 4.49Å; V137-L141 WeakPolarHBondContact O-CG 3.26Å; V137-L141 PolarHBondContact O-N 3.13Å; V137-L390 HydrophobicContact CB-CD2 4.34Å; V137-L390 HydrophobicContact CG1-CD2 3.74Å; V137-T393 HydrophobicContact CG2-CG2 3.65Å; V137-L394 HydrophobicContact CG1-CD1 4.04Å; V137-L394 HydrophobicContact CG1-CD2 4.22Å; V137-L394 HydrophobicContact CG1-CG 4.39Å; V137-L394 HydrophobicContact CG2-CD2 4.17Å; V137-L394 HydrophobicContact CG2-CG 4.45Å
138V92.8Very high87.3Confident67 Ų6749.4 Ų49.441%0.40628%0.283SS..Hα-helixtrans-63.7-43.8178.3-1780000110.5I135 S136 C140 L141 L142I135-V138 WeakPolarHBondContact O-CB 3.11Å; I135-V138 PolarHBondContact O-N 3.25Å; S136-V138 VanDerWaalsContact C-N 3.29Å; S136-V138 PolarHBondContact O-N 3.03Å; V138-C140 VanDerWaalsContact C-N 3.34Å; V138-C140 PolarHBondContact O-N 3.32Å; V138-L141 PolarHBondContact O-N 3.41Å; V138-L142 HydrophobicContact CG1-CD1 4.31Å; V138-L142 HydrophobicContact CG1-CG 4.47Å; V138-L142 WeakPolarHBondContact O-CG 3.46Å; V138-L142 PolarHBondContact O-N 3.02Å
139W95.3Very high88.2Confident20 Ų2048.4 Ų48.48%0.07628%0.277CS..Hα-helixtrans-59.8-43.6175-76.985.9000111.9T11 M14 I18 F109 A113 V116 I135 S136 L141 L142 V143T11-W139 HydrophobicContact CG2-CZ2 3.82Å; T11-W139 PolarHBondContact OG1-NE1 3.33Å; M14-W139 HydrophobicContact CB-CH2 4.16Å; M14-W139 HydrophobicContact CB-CZ2 4.28Å; M14-W139 HydrophobicContact CG-CH2 3.85Å; M14-W139 HydrophobicContact CG-CZ2 4.39Å; M14-W139 HydrophobicContact CG-CZ3 4.31Å; I18-W139 HydrophobicContact CD1-CH2 3.79Å; I18-W139 HydrophobicContact CD1-CZ3 3.78Å; F109-W139 HydrophobicContact CD2-CZ3 4.3Å; F109-W139 AromaticContact CE2-CE3 3.92Å; F109-W139 HydrophobicContact CE2-CE3 3.92Å; F109-W139 AromaticContact CE2-CZ3 3.55Å; F109-W139 HydrophobicContact CE2-CZ3 3.55Å; F109-W139 AromaticContact CZ-CE3 3.83Å; F109-W139 HydrophobicContact CZ-CE3 3.83Å; F109-W139 AromaticContact CZ-CZ3 3.96Å; F109-W139 HydrophobicContact CZ-CZ3 3.96Å; A113-W139 HydrophobicContact CB-CB 4.2Å; A113-W139 HydrophobicContact CB-CE3 4.01Å; V116-W139 HydrophobicContact CB-CG 4.5Å; V116-W139 HydrophobicContact CG1-CD2 4.42Å; V116-W139 HydrophobicContact CG1-CG 4.11Å; V116-W139 HydrophobicContact CG2-CD2 4.31Å; V116-W139 HydrophobicContact CG2-CZ2 4.29Å; I135-W139 PolarHBondContact O-N 2.9Å; S136-W139 WeakPolarHBondContact O-CB 3.45Å; S136-W139 PolarHBondContact O-N 3Å; W139-L141 PolarHBondContact O-N 3.47Å; W139-L142 PolarHBondContact O-N 3.3Å; W139-V143 WeakPolarHBondContact O-CG2 3.41Å; W139-V143 PolarHBondContact O-N 3.01Å
140C95.9Very high89.4Confident0 Ų047.9 Ų47.90%027%0.272CS..Hα-helixtrans-63.7-40.8176.6-640000112.6S136 V137 V138 V143 L144 L390S136-C140 PolarHBondContact O-N 3.48Å; S136-C140 PolarHBondContact O-SG 2.89Å; S136-C140 VanDerWaalsContact O-SG 3.33Å; V137-C140 PolarHBondContact O-N 3.02Å; V138-C140 VanDerWaalsContact C-N 3.34Å; V138-C140 PolarHBondContact O-N 3.32Å; C140-V143 PolarHBondContact O-N 3.48Å; C140-L144 WeakPolarHBondContact O-CG 3.39Å; C140-L144 PolarHBondContact O-N 3.33Å; C140-L390 HydrophobicContact CB-CD1 4.19Å; C140-L390 HydrophobicContact CB-CD2 3.79Å; C140-L390 HydrophobicContact CB-CG 3.83Å
141L95.5Very high91Very high83 Ų8343 Ų4344%0.43524%0.237SC..Hα-helixtrans-65.3-38.4175.6-69.6172.9000112.2V137 V138 W139 V143 L144 A145 L390V137-L141 HydrophobicContact CG1-CD1 4.12Å; V137-L141 HydrophobicContact CG1-CG 4.49Å; V137-L141 WeakPolarHBondContact O-CG 3.26Å; V137-L141 PolarHBondContact O-N 3.13Å; V138-L141 PolarHBondContact O-N 3.41Å; W139-L141 PolarHBondContact O-N 3.47Å; L141-V143 VanDerWaalsContact C-N 3.35Å; L141-L144 PolarHBondContact O-N 3.27Å; L141-A145 WeakPolarHBondContact O-CB 3.12Å; L141-A145 PolarHBondContact O-N 3.13Å; L141-L390 HydrophobicContact CD2-CD1 3.79Å; L141-L390 HydrophobicContact CG-CD1 4.35Å; L141-L390 HydrophobicContact CG-CD2 4.42Å
142L96Very high92.4Very high78 Ų7846 Ų4641%0.40823%0.234SC..Hα-helixtrans-62.5-41.4174-72.4173.3000111.7F109 V138 W139 A145 F146F109-L142 HydrophobicContact CE1-CB 4.01Å; F109-L142 HydrophobicContact CZ-CB 4Å; F109-L142 HydrophobicContact CZ-CD1 4.38Å; V138-L142 HydrophobicContact CG1-CD1 4.31Å; V138-L142 HydrophobicContact CG1-CG 4.47Å; V138-L142 WeakPolarHBondContact O-CG 3.46Å; V138-L142 PolarHBondContact O-N 3.02Å; W139-L142 PolarHBondContact O-N 3.3Å; L142-A145 PolarHBondContact O-N 2.71Å; L142-F146 WeakPolarHBondContact O-CG 3.38Å; L142-F146 PolarHBondContact O-N 3.26Å
143V97.4Very high93.3Very high0 Ų046.3 Ų46.30%024%0.24CC..Hα-helixtrans-60.7-46.6174.1173.20000110.7F109 A113 W139 C140 L141 A145 F146 V147 V382 H386F109-V143 HydrophobicContact CD1-CG2 3.66Å; F109-V143 HydrophobicContact CE1-CB 4.46Å; F109-V143 HydrophobicContact CE1-CG2 3.55Å; A113-V143 HydrophobicContact CB-CG2 3.35Å; W139-V143 WeakPolarHBondContact O-CG2 3.41Å; W139-V143 PolarHBondContact O-N 3.01Å; C140-V143 PolarHBondContact O-N 3.48Å; L141-V143 VanDerWaalsContact C-N 3.35Å; V143-A145 VanDerWaalsContact C-N 3.33Å; V143-A145 PolarHBondContact O-N 3.32Å; V143-F146 PolarHBondContact O-N 3.42Å; V143-V147 HydrophobicContact CG1-CG2 4.49Å; V143-V147 WeakPolarHBondContact O-CG2 3.4Å; V143-V147 PolarHBondContact O-N 3.35Å; V143-V382 HydrophobicContact CG1-CG1 3.27Å; V143-H386 HydrophobicContact CG1-CB 4.42Å
144L96.8Very high94.1Very high22 Ų2242.2 Ų42.212%0.11522%0.22CC..Hα-helixtrans-60.9-41.6176.8-69.2-177.3000112C140 L141 F146 V147 I148 M383 H386 L390C140-L144 WeakPolarHBondContact O-CG 3.39Å; C140-L144 PolarHBondContact O-N 3.33Å; L141-L144 PolarHBondContact O-N 3.27Å; L144-F146 PolarHBondContact O-N 3.21Å; L144-V147 PolarHBondContact O-N 2.91Å; L144-I148 WeakPolarHBondContact O-CG1 3.49Å; L144-I148 PolarHBondContact O-N 3.32Å; L144-M383 HydrophobicContact CD2-CB 4.46Å; L144-M383 HydrophobicContact CD2-CG 3.89Å; L144-H386 HydrophobicContact CD2-CB 3.87Å; L144-H386 HydrophobicContact CG-CB 4.12Å; L144-L390 HydrophobicContact CD1-CD1 3.46Å; L144-L390 VanDerWaalsContact CD1-CD1 3.46Å; L144-L390 HydrophobicContact CG-CD1 4.47Å
145A96.6Very high94.3Very high53 Ų5341.8 Ų41.844%0.43822%0.218SC..Hα-helixtrans-61.8-41.7175.800000112L141 L142 V143 I148 K149L141-A145 WeakPolarHBondContact O-CB 3.12Å; L141-A145 PolarHBondContact O-N 3.13Å; L142-A145 PolarHBondContact O-N 2.71Å; V143-A145 VanDerWaalsContact C-N 3.33Å; V143-A145 PolarHBondContact O-N 3.32Å; A145-I148 PolarHBondContact O-N 3.02Å; A145-K149 WeakPolarHBondContact O-CB 3.49Å; A145-K149 PolarHBondContact O-N 3.43Å
146F95.4Very high94.4Very high82 Ų8242.1 Ų42.136%0.3622%0.224SC..Hα-helixtrans-65.3-40.7174.4-73-26.1000112.9F109 L142 V143 L144 K149 I150F109-F146 AromaticContact CD1-CD2 3.44Å; F109-F146 HydrophobicContact CD1-CD2 3.44Å; F109-F146 VanDerWaalsContact CD1-CD2 3.44Å; F109-F146 AromaticContact CD1-CE2 3.56Å; F109-F146 HydrophobicContact CD1-CE2 3.56Å; F109-F146 HydrophobicContact CD2-CE2 4.18Å; F109-F146 AromaticContact CE1-CD2 3.59Å; F109-F146 HydrophobicContact CE1-CD2 3.59Å; F109-F146 AromaticContact CE1-CE2 3.49Å; F109-F146 HydrophobicContact CE1-CE2 3.49Å; F109-F146 VanDerWaalsContact CE1-CE2 3.49Å; F109-F146 HydrophobicContact CE2-CE2 4.13Å; F109-F146 HydrophobicContact CG-CD2 4.1Å; F109-F146 AromaticContact CG-CE2 3.9Å; F109-F146 HydrophobicContact CG-CE2 3.9Å; F109-F146 HydrophobicContact CZ-CD2 4.35Å; F109-F146 AromaticContact CZ-CE2 3.8Å; F109-F146 HydrophobicContact CZ-CE2 3.8Å; L142-F146 WeakPolarHBondContact O-CG 3.38Å; L142-F146 PolarHBondContact O-N 3.26Å; V143-F146 PolarHBondContact O-N 3.42Å; L144-F146 PolarHBondContact O-N 3.21Å; F146-K149 PolarHBondContact O-N 2.9Å; F146-I150 WeakPolarHBondContact O-CB 3.45Å; F146-I150 WeakPolarHBondContact O-CG1 3.41Å; F146-I150 PolarHBondContact O-N 2.87Å
147V97.1Very high94.2Very high0 Ų044.4 Ų44.40%023%0.234CC..Hα-helixtrans-60.8-48.6174.8169.40000110.9L106 V143 L144 K149 I150 L151 A379 V382 M383L106-V147 HydrophobicContact CD1-CG2 3.69Å; V143-V147 HydrophobicContact CG1-CG2 4.49Å; V143-V147 WeakPolarHBondContact O-CG2 3.4Å; V143-V147 PolarHBondContact O-N 3.35Å; L144-V147 PolarHBondContact O-N 2.91Å; V147-K149 VanDerWaalsContact C-N 3.33Å; V147-K149 PolarHBondContact O-N 3.19Å; V147-I150 PolarHBondContact O-N 2.92Å; V147-L151 HydrophobicContact CG1-CD1 3.75Å; V147-L151 HydrophobicContact CG1-CG 4.21Å; V147-L151 WeakPolarHBondContact O-CB 3.34Å; V147-L151 WeakPolarHBondContact O-CG 3.41Å; V147-L151 PolarHBondContact O-N 2.84Å; V147-A379 HydrophobicContact CG1-CB 4.13Å; V147-A379 WeakPolarHBondContact CG1-O 3.42Å; V147-V382 HydrophobicContact CG2-CB 3.94Å; V147-V382 HydrophobicContact CG2-CG1 3.55Å; V147-M383 HydrophobicContact CG1-CB 3.93Å; V147-M383 HydrophobicContact CG1-CG 4.17Å; V147-M383 HydrophobicContact CG1-SD 4.15Å
148I95.4Very high93.8Very high82 Ų8244.2 Ų44.242%0.42123%0.231SC..Hα-helixtrans-60.9-43.6178.5-67.9167.1000110.5L144 A145 I150 L151 F152 F241L144-I148 WeakPolarHBondContact O-CG1 3.49Å; L144-I148 PolarHBondContact O-N 3.32Å; A145-I148 PolarHBondContact O-N 3.02Å; I148-I150 PolarHBondContact O-N 3.34Å; I148-L151 PolarHBondContact O-N 3.42Å; I148-F152 VanDerWaalsContact O-CB 3.29Å; I148-F152 WeakPolarHBondContact O-CB 3.42Å; I148-F152 PolarHBondContact O-N 3.25Å; I148-F241 HydrophobicContact CG2-CE2 4.26Å
149K95.6Very high93.3Very high141 Ų14144.5 Ų44.561%0.61323%0.227SC*.Hα-helixtrans-56.9-47.8175.1-179.9-159.6168.9-175.80111.5A145 F146 V147 F152 S153A145-K149 WeakPolarHBondContact O-CB 3.49Å; A145-K149 PolarHBondContact O-N 3.43Å; F146-K149 PolarHBondContact O-N 2.9Å; V147-K149 VanDerWaalsContact C-N 3.33Å; V147-K149 PolarHBondContact O-N 3.19Å; K149-F152 PolarHBondContact O-N 3.35Å; K149-S153 WeakPolarHBondContact O-CB 3.44Å; K149-S153 PolarHBondContact O-N 3.38Å
150I94.7Very high92.7Very high16 Ų1651.5 Ų51.58%0.08226%0.259CS..Hα-helixtrans-66.5-47-178.4-72.3169.7000110.4L106 F146 V147 I148 F152 S153 L154 L375L106-I150 HydrophobicContact CB-CD1 3.62Å; L106-I150 HydrophobicContact CD1-CD1 4.02Å; L106-I150 HydrophobicContact CD2-CD1 3.85Å; L106-I150 HydrophobicContact CG-CD1 4.01Å; F146-I150 WeakPolarHBondContact O-CB 3.45Å; F146-I150 WeakPolarHBondContact O-CG1 3.41Å; F146-I150 PolarHBondContact O-N 2.87Å; V147-I150 PolarHBondContact O-N 2.92Å; I148-I150 PolarHBondContact O-N 3.34Å; I150-F152 VanDerWaalsContact C-N 3.3Å; I150-F152 PolarHBondContact O-N 3.24Å; I150-S153 WeakPolarHBondContact O-CB 3.45Å; I150-S153 PolarHBondContact O-N 2.95Å; I150-S153 VanDerWaalsContact O-N 3.11Å; I150-L154 HydrophobicContact CG2-CD1 4.1Å; I150-L154 HydrophobicContact CG2-CG 4.32Å; I150-L154 WeakPolarHBondContact O-CG 3.29Å; I150-L154 PolarHBondContact O-N 2.87Å; I150-L375 HydrophobicContact CD1-CD2 4.33Å; I150-L375 HydrophobicContact CG2-CD1 4.16Å; I150-L375 HydrophobicContact CG2-CD2 3.97Å; I150-L375 HydrophobicContact CG2-CG 4.46Å
151L94.8Very high91.7Very high3 Ų354.8 Ų54.82%0.01628%0.276CS..Hα-helixtrans-59.1-43.3177.1-71.7175000111.4V147 I148 S153 L154 T155 F241 L242 P245 A379 M383V147-L151 HydrophobicContact CG1-CD1 3.75Å; V147-L151 HydrophobicContact CG1-CG 4.21Å; V147-L151 WeakPolarHBondContact O-CB 3.34Å; V147-L151 WeakPolarHBondContact O-CG 3.41Å; V147-L151 PolarHBondContact O-N 2.84Å; I148-L151 PolarHBondContact O-N 3.42Å; L151-S153 PolarHBondContact O-N 3.49Å; L151-L154 PolarHBondContact O-N 3.29Å; L151-T155 WeakPolarHBondContact O-CB 3.37Å; L151-T155 PolarHBondContact O-N 3.36Å; L151-T155 PolarHBondContact O-OG1 3.4Å; L151-T155 VanDerWaalsContact O-OG1 3.09Å; L151-F241 HydrophobicContact CB-CB 4.02Å; L151-F241 HydrophobicContact CB-CD2 4.32Å; L151-F241 HydrophobicContact CB-CG 4.2Å; L151-F241 HydrophobicContact CD1-CB 4.29Å; L151-L242 HydrophobicContact CD1-CD2 4.32Å; L151-P245 HydrophobicContact CD2-CG 4.19Å; L151-A379 HydrophobicContact CD2-CB 3.9Å; L151-A379 HydrophobicContact CG-CB 4.17Å; L151-M383 HydrophobicContact CD1-CE 4.48Å; L151-M383 HydrophobicContact CD1-SD 4.33Å
152F94.4Very high90Very high126 Ų12660.2 Ų60.255%0.55330%0.299SS*.Hα-helixtrans-60.1-45.2173.1175.9-99.7000112.1I148 K149 I150 L154 T155 A156 F241I148-F152 VanDerWaalsContact O-CB 3.29Å; I148-F152 WeakPolarHBondContact O-CB 3.42Å; I148-F152 PolarHBondContact O-N 3.25Å; K149-F152 PolarHBondContact O-N 3.35Å; I150-F152 VanDerWaalsContact C-N 3.3Å; I150-F152 PolarHBondContact O-N 3.24Å; F152-L154 VanDerWaalsContact C-N 3.33Å; F152-L154 PolarHBondContact O-N 3.26Å; F152-T155 PolarHBondContact O-N 3.5Å; F152-A156 VanDerWaalsContact O-CB 3.24Å; F152-A156 WeakPolarHBondContact O-CB 3.26Å; F152-A156 PolarHBondContact O-N 3.44Å; F152-F241 HydrophobicContact CB-CE1 4.35Å; F152-F241 HydrophobicContact CB-CE2 4.45Å; F152-F241 HydrophobicContact CB-CZ 3.98Å; F152-F241 HydrophobicContact CD2-CE1 4.06Å; F152-F241 AromaticContact CD2-CZ 3.82Å; F152-F241 HydrophobicContact CD2-CZ 3.82Å; F152-F241 HydrophobicContact CG-CZ 4.41Å
153S93.6Very high88.7Confident43 Ų4364 Ų6430%0.30132%0.315SS..Hα-helixtrans-60.6-41.9177.3-167.60000112.1Y99 K149 I150 L151 A156 H157Y99-S153 PolarHBondContact OH-OG 3.48Å; K149-S153 WeakPolarHBondContact O-CB 3.44Å; K149-S153 PolarHBondContact O-N 3.38Å; I150-S153 WeakPolarHBondContact O-CB 3.45Å; I150-S153 PolarHBondContact O-N 2.95Å; I150-S153 VanDerWaalsContact O-N 3.11Å; L151-S153 PolarHBondContact O-N 3.49Å; S153-A156 PolarHBondContact O-N 3.02Å; S153-H157 PolarHBondContact O-N 2.75Å
154L91.1Very high87.4Confident5 Ų566.2 Ų66.23%0.02634%0.337CS..Hα-helixtrans-65-49.5176.3-68.9179000111Y99 I150 L151 F152 A156 H157 Y158 V372 L375 Q376Y99-L154 HydrophobicContact CE1-CD2 4.47Å; I150-L154 HydrophobicContact CG2-CD1 4.1Å; I150-L154 HydrophobicContact CG2-CG 4.32Å; I150-L154 WeakPolarHBondContact O-CG 3.29Å; I150-L154 PolarHBondContact O-N 2.87Å; L151-L154 PolarHBondContact O-N 3.29Å; F152-L154 VanDerWaalsContact C-N 3.33Å; F152-L154 PolarHBondContact O-N 3.26Å; L154-A156 VanDerWaalsContact C-N 3.33Å; L154-A156 PolarHBondContact O-N 2.9Å; L154-H157 WeakPolarHBondContact O-CB 3.35Å; L154-H157 PolarHBondContact O-N 3.02Å; L154-H157 VanDerWaalsContact O-N 3.12Å; L154-Y158 WeakPolarHBondContact O-CD2 3.33Å; L154-Y158 PolarHBondContact O-N 3.02Å; L154-Y158 VanDerWaalsContact O-N 3.16Å; L154-V372 HydrophobicContact CD2-CG1 3.7Å; L154-L375 HydrophobicContact CD1-CB 4.1Å; L154-Q376 HydrophobicContact CD1-CG 3.95Å
155T90.8Very high86.8Confident13 Ų1367.4 Ų67.48%0.0836%0.355CS..Hα-helixtrans-59.2-44.2175.6-59.80000111.1L151 F152 H157 Y158 F159 F241L151-T155 WeakPolarHBondContact O-CB 3.37Å; L151-T155 PolarHBondContact O-N 3.36Å; L151-T155 PolarHBondContact O-OG1 3.4Å; L151-T155 VanDerWaalsContact O-OG1 3.09Å; F152-T155 PolarHBondContact O-N 3.5Å; T155-H157 PolarHBondContact O-N 3.29Å; T155-Y158 WeakPolarHBondContact O-CB 3.2Å; T155-Y158 PolarHBondContact O-N 2.6Å; T155-Y158 VanDerWaalsContact O-N 3.12Å; T155-F159 HydrophobicContact CG2-CD2 3.89Å; T155-F159 HydrophobicContact CG2-CE2 3.73Å; T155-F159 VanDerWaalsContact O-CD2 3.26Å; T155-F159 WeakPolarHBondContact O-CD2 3.39Å; T155-F159 PolarHBondContact O-N 2.89Å; T155-F241 HydrophobicContact CG2-CD1 4.29Å; T155-F241 HydrophobicContact CG2-CE1 4.45Å; T155-F241 WeakPolarHBondContact OG1-CD1 3.47Å
156A90.3Very high86.2Confident30 Ų3067.9 Ų67.925%0.24835%0.348CS..Hα-helixtrans-61.7-32.2177.100000112.6F152 S153 L154 F159 K160F152-A156 VanDerWaalsContact O-CB 3.24Å; F152-A156 WeakPolarHBondContact O-CB 3.26Å; F152-A156 PolarHBondContact O-N 3.44Å; S153-A156 PolarHBondContact O-N 3.02Å; L154-A156 VanDerWaalsContact C-N 3.33Å; L154-A156 PolarHBondContact O-N 2.9Å; A156-F159 PolarHBondContact O-N 3.02Å; A156-K160 WeakPolarHBondContact O-CG 3.33Å; A156-K160 PolarHBondContact O-N 3.35Å
157H87.1Confident85.9Confident47 Ų4768.1 Ų68.122%0.21835%0.346CS..Hα-helixtrans-64.9-46173.2-173.175.2000111.6Y98 S153 L154 T155 F159 K160Y98-H157 AromaticContact CE1-CE1 3.82Å; Y98-H157 PolarHBondContact OH-CE1 3.17Å; Y98-H157 PolarHBondContact OH-ND1 2.99Å; S153-H157 PolarHBondContact O-N 2.75Å; L154-H157 WeakPolarHBondContact O-CB 3.35Å; L154-H157 PolarHBondContact O-N 3.02Å; L154-H157 VanDerWaalsContact O-N 3.12Å; T155-H157 PolarHBondContact O-N 3.29Å; H157-F159 PolarHBondContact O-N 3.17Å; H157-K160 PolarHBondContact O-N 3.32Å
158Y82.4Confident85.5Confident17 Ų1771.2 Ų71.27%0.06737%0.368CS..Hα-helixtrans-59.5-34.5173.1-69.8-67000112.6L154 T155 K160 L161 E166 F244 Y369 Q376L154-Y158 WeakPolarHBondContact O-CD2 3.33Å; L154-Y158 PolarHBondContact O-N 3.02Å; L154-Y158 VanDerWaalsContact O-N 3.16Å; T155-Y158 WeakPolarHBondContact O-CB 3.2Å; T155-Y158 PolarHBondContact O-N 2.6Å; T155-Y158 VanDerWaalsContact O-N 3.12Å; Y158-K160 PolarHBondContact O-N 3.01Å; Y158-L161 HydrophobicContact CD1-CD1 4.16Å; Y158-L161 PolarHBondContact O-N 3.47Å; Y158-E166 WeakPolarHBondContact CD1-OE2 3.4Å; Y158-F244 HydrophobicContact CD1-CE1 4.44Å; Y158-F244 HydrophobicContact CD1-CZ 4.43Å; Y158-F244 AromaticContact CD2-CD2 3.66Å; Y158-F244 HydrophobicContact CD2-CD2 3.66Å; Y158-F244 AromaticContact CD2-CE2 3.88Å; Y158-F244 HydrophobicContact CD2-CE2 3.88Å; Y158-F244 HydrophobicContact CD2-CG 4.04Å; Y158-F244 HydrophobicContact CD2-CZ 4.44Å; Y158-F244 HydrophobicContact CE2-CB 4.11Å; Y158-F244 HydrophobicContact CE2-CD2 4.07Å; Y158-F244 HydrophobicContact CE2-CG 4.03Å; Y158-F244 HydrophobicContact CG-CD2 4.1Å; Y158-F244 HydrophobicContact CG-CE1 4.44Å; Y158-F244 AromaticContact CG-CE2 3.88Å; Y158-F244 HydrophobicContact CG-CE2 3.88Å; Y158-F244 HydrophobicContact CG-CG 4.46Å; Y158-F244 HydrophobicContact CG-CZ 4.06Å; Y158-Y369 VanDerWaalsContact CZ-OH 3.3Å; Y158-Y369 PolarHBondContact OH-OH 2.94Å; Y158-Q376 VanDerWaalsContact CE2-NE2 3.31Å; Y158-Q376 PolarHBondContact OH-NE2 3.31Å
159F83.2Confident85.2Confident73 Ų7370.5 Ų70.532%0.3237%0.365SS..THydrogen-bonded Turntrans-73.1-11.6175.9-87.1-108.7000115T155 A156 H157 R167 C170 I171T155-F159 HydrophobicContact CG2-CD2 3.89Å; T155-F159 HydrophobicContact CG2-CE2 3.73Å; T155-F159 VanDerWaalsContact O-CD2 3.26Å; T155-F159 WeakPolarHBondContact O-CD2 3.39Å; T155-F159 PolarHBondContact O-N 2.89Å; A156-F159 PolarHBondContact O-N 3.02Å; H157-F159 PolarHBondContact O-N 3.17Å; F159-R167 HydrophobicContact CD1-CB 4.48Å; F159-R167 HydrophobicContact CD1-CG 4.28Å; F159-R167 HydrophobicContact CE1-CB 4.45Å; F159-R167 HydrophobicContact CG-CG 4.37Å; F159-R167 PolarHBondContact O-NE 2.94Å; F159-R167 PolarHBondContact O-NH2 3.27Å; F159-C170 HydrophobicContact CE2-CB 3.67Å; F159-C170 HydrophobicContact CZ-CB 4.01Å; F159-I171 HydrophobicContact CE1-CD1 4.27Å; F159-I171 HydrophobicContact CE1-CG1 4.29Å; F159-I171 HydrophobicContact CZ-CG1 4.07Å
160K83Confident85Confident168 Ų16864 Ų6473%0.7334%0.337SS*.THydrogen-bonded Turntrans-94.5-18.1177.2-73.5175.3-178.4-177.80113.1A156 H157 Y158 R167A156-K160 WeakPolarHBondContact O-CG 3.33Å; A156-K160 PolarHBondContact O-N 3.35Å; H157-K160 PolarHBondContact O-N 3.32Å; Y158-K160 PolarHBondContact O-N 3.01Å; K160-R167 PolarHBondContact O-NH2 3.25Å
161L75.5Confident85Confident69 Ų6968.1 Ų68.136%0.36136%0.358SS..SBendtrans-64.6136.8178.9-70.7165.5000110.7Y158 E163 E166 R167Y158-L161 HydrophobicContact CD1-CD1 4.16Å; Y158-L161 PolarHBondContact O-N 3.47Å; L161-E163 PolarHBondContact O-N 2.62Å; L161-E166 WeakPolarHBondContact CD1-OE2 3.44Å; L161-R167 VanDerWaalsContact O-CZ 3.26Å; L161-R167 PolarHBondContact O-NE 3.07Å; L161-R167 VanDerWaalsContact O-NE 3.13Å; L161-R167 PolarHBondContact O-NH2 3.3Å
162E58.5Low84.9Confident197 Ų19772.3 Ų72.392%0.92138%0.384SS*.SBendtrans-64.7-22.8-173.6-74.4-177.515300113.1G164E162-G164 PolarHBondContact O-N 2.94Å
163E70.2Confident84.9Confident158 Ų15867.1 Ų67.174%0.73836%0.361SS*.  trans-76.9111.4177.2-65.1-177.5-173.900110.8L161 G165L161-E163 PolarHBondContact O-N 2.62Å; E163-G165 PolarHBondContact O-N 3.27Å; E163-G165 VanDerWaalsContact O-N 3.07Å
164G69.8Low85.1Confident46 Ų4666.1 Ų66.147%0.47436%0.355SS..Hα-helixtrans-65.8-9.4-175.600000115.9E162 R167 S168E162-G164 PolarHBondContact O-N 2.94Å; G164-R167 PolarHBondContact O-N 2.95Å; G164-S168 PolarHBondContact O-N 3.34Å; G164-S168 VanDerWaalsContact O-N 3.13Å; G164-S168 PolarHBondContact O-OG 3.44Å
165G83.4Confident85.3Confident47 Ų4772.4 Ų72.449%0.48538%0.383SS..Hα-helixtrans-67-40.1-175.300000114.2E163 S168 L169E163-G165 PolarHBondContact O-N 3.27Å; E163-G165 VanDerWaalsContact O-N 3.07Å; G165-S168 PolarHBondContact O-OG 2.91Å; G165-L169 WeakPolarHBondContact O-CB 3.5Å; G165-L169 PolarHBondContact O-N 2.91Å
166E84.8Confident85.6Confident63 Ų6375.4 Ų75.429%0.29440%0.395SS..Hα-helixtrans-70.1-36.7179.3-64.7-178.4146.900111.4Y158 L161 L169 C170 F244Y158-E166 WeakPolarHBondContact CD1-OE2 3.4Å; L161-E166 WeakPolarHBondContact CD1-OE2 3.44Å; E166-L169 PolarHBondContact O-N 3.47Å; E166-C170 PolarHBondContact O-N 3.22Å; E166-F244 HydrophobicContact CB-CE1 4.14Å; E166-F244 HydrophobicContact CB-CZ 4Å; E166-F244 HydrophobicContact CG-CE1 4.44Å; E166-F244 WeakPolarHBondContact O-CZ 3.42Å
167R87.5Confident86Confident87 Ų8774 Ų7433%0.32838%0.383SS..Hα-helixtrans-62.5-49.9176.7-59.1-179.2-169.3-167.1-1.9111.1F159 K160 L161 G164 L169 C170 I171F159-R167 HydrophobicContact CD1-CB 4.48Å; F159-R167 HydrophobicContact CD1-CG 4.28Å; F159-R167 HydrophobicContact CE1-CB 4.45Å; F159-R167 HydrophobicContact CG-CG 4.37Å; F159-R167 PolarHBondContact O-NE 2.94Å; F159-R167 PolarHBondContact O-NH2 3.27Å; K160-R167 PolarHBondContact O-NH2 3.25Å; L161-R167 VanDerWaalsContact O-CZ 3.26Å; L161-R167 PolarHBondContact O-NE 3.07Å; L161-R167 VanDerWaalsContact O-NE 3.13Å; L161-R167 PolarHBondContact O-NH2 3.3Å; G164-R167 PolarHBondContact O-N 2.95Å; R167-L169 VanDerWaalsContact C-N 3.34Å; R167-C170 PolarHBondContact O-N 3.33Å; R167-I171 WeakPolarHBondContact O-CG1 3.33Å; R167-I171 PolarHBondContact O-N 3.28Å; R167-I171 VanDerWaalsContact O-N 3.13Å
168S88.8Confident86.5Confident64 Ų6474.4 Ų74.445%0.44838%0.384SS..Hα-helixtrans-63.6-43179.562.40000110.9G164 G165 C170 I171 T172G164-S168 PolarHBondContact O-N 3.34Å; G164-S168 VanDerWaalsContact O-N 3.13Å; G164-S168 PolarHBondContact O-OG 3.44Å; G165-S168 PolarHBondContact O-OG 2.91Å; S168-C170 PolarHBondContact O-N 2.87Å; S168-I171 PolarHBondContact O-N 3.21Å; S168-T172 PolarHBondContact O-N 3.32Å; S168-T172 PolarHBondContact O-OG1 3.44Å
169L90.4Very high87.2Confident68 Ų6876.4 Ų76.436%0.35640%0.398SS..Hα-helixtrans-56.8-48.5176.7-169.766.8000111.8G165 E166 R167 I171 T172 F173 L247G165-L169 WeakPolarHBondContact O-CB 3.5Å; G165-L169 PolarHBondContact O-N 2.91Å; E166-L169 PolarHBondContact O-N 3.47Å; R167-L169 VanDerWaalsContact C-N 3.34Å; L169-I171 PolarHBondContact O-N 2.9Å; L169-T172 PolarHBondContact O-N 2.87Å; L169-F173 HydrophobicContact CD1-CD2 4Å; L169-F173 HydrophobicContact CD1-CE2 3.7Å; L169-F173 HydrophobicContact CG-CD2 4.01Å; L169-F173 HydrophobicContact CG-CE2 4.02Å; L169-F173 WeakPolarHBondContact O-CD2 3.32Å; L169-F173 PolarHBondContact O-N 3.42Å; L169-L247 HydrophobicContact CD2-CD1 3.63Å; L169-L247 HydrophobicContact CG-CD1 4.48Å
170C91.9Very high87.7Confident4 Ų474.7 Ų74.73%0.02739%0.39CS..Hα-helixtrans-62.1-40.7179.1-170.10000112.5F159 E166 R167 S168 F173 A174 F244F159-C170 HydrophobicContact CE2-CB 3.67Å; F159-C170 HydrophobicContact CZ-CB 4.01Å; E166-C170 PolarHBondContact O-N 3.22Å; R167-C170 PolarHBondContact O-N 3.33Å; S168-C170 PolarHBondContact O-N 2.87Å; C170-F173 PolarHBondContact O-N 2.92Å; C170-A174 WeakPolarHBondContact O-CB 3.14Å; C170-A174 PolarHBondContact O-N 3.44Å; C170-F244 HydrophobicContact CB-CE2 3.86Å; C170-F244 HydrophobicContact CB-CZ 4.06Å
171I92.9Very high88.4Confident102 Ų10266.7 Ų66.752%0.52336%0.355SS..Hα-helixtrans-66.4-42.6177.5-66.2167.2000110.7F159 R167 S168 L169 F173 A174 F175F159-I171 HydrophobicContact CE1-CD1 4.27Å; F159-I171 HydrophobicContact CE1-CG1 4.29Å; F159-I171 HydrophobicContact CZ-CG1 4.07Å; R167-I171 WeakPolarHBondContact O-CG1 3.33Å; R167-I171 PolarHBondContact O-N 3.28Å; R167-I171 VanDerWaalsContact O-N 3.13Å; S168-I171 PolarHBondContact O-N 3.21Å; L169-I171 PolarHBondContact O-N 2.9Å; I171-F173 PolarHBondContact O-N 3.46Å; I171-A174 WeakPolarHBondContact O-CB 3.47Å; I171-A174 PolarHBondContact O-N 3.36Å; I171-F175 PolarHBondContact O-N 3.43Å
172T94.1Very high89.3Confident91 Ų9166 Ų6656%0.55835%0.351SS*.Hα-helixtrans-60.6-44.5176.5-59.20000111.3S168 L169 F175 F176S168-T172 PolarHBondContact O-N 3.32Å; S168-T172 PolarHBondContact O-OG1 3.44Å; L169-T172 PolarHBondContact O-N 2.87Å; T172-F175 PolarHBondContact O-N 3.49Å; T172-F176 WeakPolarHBondContact O-CB 3.48Å; T172-F176 PolarHBondContact O-N 3.11Å
173F94.7Very high90.9Very high18 Ų1861.5 Ų61.58%0.07933%0.332CS..Hα-helixtrans-66.7-36.2175.7-88.1-80.9000112.8L169 C170 I171 F175 F176 F177 T243 L247 T478 F481L169-F173 HydrophobicContact CD1-CD2 4Å; L169-F173 HydrophobicContact CD1-CE2 3.7Å; L169-F173 HydrophobicContact CG-CD2 4.01Å; L169-F173 HydrophobicContact CG-CE2 4.02Å; L169-F173 WeakPolarHBondContact O-CD2 3.32Å; L169-F173 PolarHBondContact O-N 3.42Å; C170-F173 PolarHBondContact O-N 2.92Å; I171-F173 PolarHBondContact O-N 3.46Å; F173-F175 VanDerWaalsContact C-N 3.33Å; F173-F175 PolarHBondContact O-N 3.09Å; F173-F176 HydrophobicContact CD1-CD1 4.31Å; F173-F176 PolarHBondContact O-N 2.87Å; F173-F177 HydrophobicContact CB-CD2 4.38Å; F173-F177 HydrophobicContact CB-CE2 4.4Å; F173-F177 HydrophobicContact CD1-CD2 4.44Å; F173-F177 AromaticContact CD1-CE2 3.81Å; F173-F177 HydrophobicContact CD1-CE2 3.81Å; F173-F177 HydrophobicContact CD1-CZ 4.47Å; F173-F177 WeakPolarHBondContact O-CB 3.37Å; F173-F177 WeakPolarHBondContact O-CD2 3.5Å; F173-F177 PolarHBondContact O-N 2.77Å; F173-T243 HydrophobicContact CB-CG2 3.7Å; F173-T243 WeakPolarHBondContact CB-OG1 3.4Å; F173-T243 HydrophobicContact CD1-CG2 4.14Å; F173-T243 HydrophobicContact CD2-CG2 3.29Å; F173-T243 HydrophobicContact CE2-CG2 3.87Å; F173-T243 HydrophobicContact CG-CG2 3.44Å; F173-T243 VanDerWaalsContact CG-CG2 3.44Å; F173-L247 HydrophobicContact CE2-CD1 4.4Å; F173-L247 HydrophobicContact CZ-CD2 4.42Å; F173-T478 HydrophobicContact CE1-CG2 4.5Å; F173-F481 HydrophobicContact CE1-CB 4.26Å; F173-F481 AromaticContact CE1-CD2 3.71Å; F173-F481 HydrophobicContact CE1-CD2 3.71Å; F173-F481 HydrophobicContact CE1-CE2 4.25Å; F173-F481 HydrophobicContact CE1-CG 4.02Å; F173-F481 HydrophobicContact CZ-CB 3.87Å; F173-F481 HydrophobicContact CZ-CD1 4.46Å; F173-F481 HydrophobicContact CZ-CD2 4.09Å; F173-F481 AromaticContact CZ-CG 3.9Å; F173-F481 HydrophobicContact CZ-CG 3.9Å
174A95.9Very high92Very high21 Ų2155.3 Ų55.317%0.17430%0.304CS..Hα-helixtrans-58-46.6173.800000111.2C170 I171 F177 F178 S236 A240C170-A174 WeakPolarHBondContact O-CB 3.14Å; C170-A174 PolarHBondContact O-N 3.44Å; I171-A174 WeakPolarHBondContact O-CB 3.47Å; I171-A174 PolarHBondContact O-N 3.36Å; A174-F177 PolarHBondContact O-N 3.28Å; A174-F178 WeakPolarHBondContact O-CB 3.35Å; A174-F178 PolarHBondContact O-N 2.78Å; A174-S236 PolarHBondContact O-OG 3.41Å; A174-A240 HydrophobicContact CB-CB 3.79Å
175F97Very high93.1Very high138 Ų13853.5 Ų53.561%0.60528%0.284SS*.Hα-helixtrans-65.3-44176-177.1-100.6000112.4I171 T172 F173 F177 F178 V179I171-F175 PolarHBondContact O-N 3.43Å; T172-F175 PolarHBondContact O-N 3.49Å; F173-F175 VanDerWaalsContact C-N 3.33Å; F173-F175 PolarHBondContact O-N 3.09Å; F175-F177 VanDerWaalsContact C-N 3.32Å; F175-F177 PolarHBondContact O-N 3.12Å; F175-F178 WeakPolarHBondContact O-CB 3.46Å; F175-F178 PolarHBondContact O-N 3.42Å; F175-V179 HydrophobicContact CD1-CG2 4.33Å; F175-V179 HydrophobicContact CE1-CG2 3.86Å; F175-V179 HydrophobicContact CE2-CG2 4.3Å; F175-V179 HydrophobicContact CZ-CG2 3.84Å; F175-V179 PolarHBondContact O-N 3.36Å
176F96.8Very high93.4Very high76 Ų7657 Ų5733%0.33329%0.29SS..Hα-helixtrans-55.8-46.4174.6170.1-99.4000111.7T172 F173 V179 K180 F481T172-F176 WeakPolarHBondContact O-CB 3.48Å; T172-F176 PolarHBondContact O-N 3.11Å; F173-F176 HydrophobicContact CD1-CD1 4.31Å; F173-F176 PolarHBondContact O-N 2.87Å; F176-V179 PolarHBondContact O-N 3.4Å; F176-K180 HydrophobicContact CE1-CD 4.31Å; F176-K180 WeakPolarHBondContact O-CB 3.49Å; F176-K180 PolarHBondContact O-N 3.12Å; F176-F481 AromaticContact CE1-CE2 3.96Å; F176-F481 HydrophobicContact CE1-CE2 3.96Å; F176-F481 HydrophobicContact CE2-CE2 4.3Å; F176-F481 HydrophobicContact CE2-CZ 4.31Å; F176-F481 AromaticContact CZ-CE2 3.77Å; F176-F481 HydrophobicContact CZ-CE2 3.77Å; F176-F481 HydrophobicContact CZ-CZ 4.22Å
177F97.6Very high93.6Very high0 Ų056.6 Ų56.60%029%0.292CS..Hα-helixtrans-69.4-32.2178.2-79.8-57.5000113.2F173 A174 F175 K180 A181 G239 W470 C474 T478F173-F177 HydrophobicContact CB-CD2 4.38Å; F173-F177 HydrophobicContact CB-CE2 4.4Å; F173-F177 HydrophobicContact CD1-CD2 4.44Å; F173-F177 AromaticContact CD1-CE2 3.81Å; F173-F177 HydrophobicContact CD1-CE2 3.81Å; F173-F177 HydrophobicContact CD1-CZ 4.47Å; F173-F177 WeakPolarHBondContact O-CB 3.37Å; F173-F177 WeakPolarHBondContact O-CD2 3.5Å; F173-F177 PolarHBondContact O-N 2.77Å; A174-F177 PolarHBondContact O-N 3.28Å; F175-F177 VanDerWaalsContact C-N 3.32Å; F175-F177 PolarHBondContact O-N 3.12Å; F177-K180 HydrophobicContact CD1-CD 4.07Å; F177-K180 HydrophobicContact CE1-CD 4.15Å; F177-A181 VanDerWaalsContact O-CB 3.24Å; F177-A181 WeakPolarHBondContact O-CB 3.43Å; F177-A181 PolarHBondContact O-N 2.99Å; F177-G239 VanDerWaalsContact CD2-C 3.43Å; F177-G239 WeakPolarHBondContact CE2-O 3.27Å; F177-W470 HydrophobicContact CB-CZ2 4.09Å; F177-W470 HydrophobicContact CD1-CH2 4.15Å; F177-W470 AromaticContact CD1-CZ2 3.83Å; F177-W470 HydrophobicContact CD1-CZ2 3.83Å; F177-W470 HydrophobicContact CG-CZ2 4.35Å; F177-W470 WeakPolarHBondContact O-CH2 3.25Å; F177-C474 VanDerWaalsContact CD1-SG 3.56Å; F177-C474 HydrophobicContact CE1-CB 4.1Å; F177-C474 VanDerWaalsContact CE1-SG 3.5Å; F177-C474 HydrophobicContact CZ-CB 4.23Å; F177-T478 HydrophobicContact CE2-CG2 3.71Å; F177-T478 HydrophobicContact CZ-CG2 3.63Å
178F97.7Very high93.3Very high55 Ų5555.8 Ų55.824%0.24130%0.296CS..Hα-helixtrans-61.2-51171.9179.7-102.4000111.5A174 F175 K180 A181 M182 A232 L233A174-F178 WeakPolarHBondContact O-CB 3.35Å; A174-F178 PolarHBondContact O-N 2.78Å; F175-F178 WeakPolarHBondContact O-CB 3.46Å; F175-F178 PolarHBondContact O-N 3.42Å; F178-K180 PolarHBondContact O-N 3.16Å; F178-A181 PolarHBondContact O-N 2.92Å; F178-M182 HydrophobicContact CE1-CG 4.2Å; F178-M182 HydrophobicContact CE2-CG 4.5Å; F178-M182 HydrophobicContact CZ-CG 4.15Å; F178-M182 WeakPolarHBondContact O-CG 3.33Å; F178-M182 PolarHBondContact O-N 3.32Å; F178-A232 HydrophobicContact CD2-CB 4.22Å; F178-A232 HydrophobicContact CE2-CB 3.97Å; F178-L233 HydrophobicContact CD2-CD2 4.15Å; F178-L233 HydrophobicContact CE2-CD2 3.81Å; F178-L233 HydrophobicContact CE2-CG 4.2Å
179V96.8Very high93Very high59 Ų5954.8 Ų54.836%0.35829%0.285SS..Hα-helixtrans-62.8-45.1178.2176.20000110.8F175 F176 A181 M182 I183F175-V179 HydrophobicContact CD1-CG2 4.33Å; F175-V179 HydrophobicContact CE1-CG2 3.86Å; F175-V179 HydrophobicContact CE2-CG2 4.3Å; F175-V179 HydrophobicContact CZ-CG2 3.84Å; F175-V179 PolarHBondContact O-N 3.36Å; F176-V179 PolarHBondContact O-N 3.4Å; V179-A181 VanDerWaalsContact C-N 3.31Å; V179-A181 PolarHBondContact O-N 3.02Å; V179-M182 PolarHBondContact O-N 3.19Å; V179-I183 HydrophobicContact CG1-CD1 4.05Å; V179-I183 WeakPolarHBondContact O-CG1 3.45Å; V179-I183 PolarHBondContact O-N 3.46Å
180K95.5Very high92.6Very high37 Ų3757.3 Ų57.316%0.16130%0.298CS..Hα-helixtrans-57.6-43.9175.3-175-171.8174.3-162.80111.4F176 F177 F178 I183 I184 W470 A473 S477F176-K180 HydrophobicContact CE1-CD 4.31Å; F176-K180 WeakPolarHBondContact O-CB 3.49Å; F176-K180 PolarHBondContact O-N 3.12Å; F177-K180 HydrophobicContact CD1-CD 4.07Å; F177-K180 HydrophobicContact CE1-CD 4.15Å; F178-K180 PolarHBondContact O-N 3.16Å; K180-I183 PolarHBondContact O-N 3.47Å; K180-I184 VanDerWaalsContact O-CG1 3.32Å; K180-I184 WeakPolarHBondContact O-CG1 3.33Å; K180-I184 PolarHBondContact O-N 2.92Å; K180-W470 HydrophobicContact CB-CH2 4.11Å; K180-W470 HydrophobicContact CD-CH2 4.04Å; K180-W470 HydrophobicContact CD-CZ3 4.3Å; K180-W470 HydrophobicContact CG-CH2 4.03Å; K180-W470 HydrophobicContact CG-CZ3 4.22Å; K180-A473 PolarHBondContact NZ-O 3.2Å; K180-A473 VanDerWaalsContact NZ-O 3.14Å; K180-S477 PolarHBondContact NZ-OG 3.09Å
181A95.9Very high92.2Very high0 Ų064 Ų640%032%0.324CS..Hα-helixtrans-63.3-44.2178.800000111.3F177 F178 V179 I183 I184 L185 A232 C235 W470F177-A181 VanDerWaalsContact O-CB 3.24Å; F177-A181 WeakPolarHBondContact O-CB 3.43Å; F177-A181 PolarHBondContact O-N 2.99Å; F178-A181 PolarHBondContact O-N 2.92Å; V179-A181 VanDerWaalsContact C-N 3.31Å; V179-A181 PolarHBondContact O-N 3.02Å; A181-I183 VanDerWaalsContact C-N 3.34Å; A181-I183 PolarHBondContact O-N 3.34Å; A181-I184 PolarHBondContact O-N 3.07Å; A181-L185 WeakPolarHBondContact O-CB 3.41Å; A181-L185 VanDerWaalsContact O-CG 3.24Å; A181-L185 WeakPolarHBondContact O-CG 3.45Å; A181-L185 PolarHBondContact O-N 2.67Å; A181-A232 HydrophobicContact CB-CB 4.16Å; A181-C235 HydrophobicContact CB-CB 3.58Å; A181-W470 HydrophobicContact CB-CH2 3.53Å; A181-W470 HydrophobicContact CB-CZ2 3.96Å; A181-W470 HydrophobicContact CB-CZ3 3.97Å
182M94.4Very high91.9Very high55 Ų5559.9 Ų59.927%0.27130%0.303SS..Hα-helixtrans-59.6-43.5176.9-74.8-64.6-70.500112.2F178 V179 L185 I186 A232F178-M182 HydrophobicContact CE1-CG 4.2Å; F178-M182 HydrophobicContact CE2-CG 4.5Å; F178-M182 HydrophobicContact CZ-CG 4.15Å; F178-M182 WeakPolarHBondContact O-CG 3.33Å; F178-M182 PolarHBondContact O-N 3.32Å; V179-M182 PolarHBondContact O-N 3.19Å; M182-L185 PolarHBondContact O-N 3.27Å; M182-I186 WeakPolarHBondContact O-CD1 3.05Å; M182-I186 VanDerWaalsContact O-CG1 3.28Å; M182-I186 WeakPolarHBondContact O-CG1 3.24Å; M182-I186 PolarHBondContact O-N 2.9Å; M182-A232 HydrophobicContact CG-CB 4.05Å; M182-A232 HydrophobicContact SD-CB 3.68Å
183I93.6Very high91.5Very high103 Ų10357 Ų5753%0.52828%0.283SS..Hα-helixtrans-60.5-49.6176.1-67.2166.8000110.3V179 K180 A181 L185 I186 V187V179-I183 HydrophobicContact CG1-CD1 4.05Å; V179-I183 WeakPolarHBondContact O-CG1 3.45Å; V179-I183 PolarHBondContact O-N 3.46Å; K180-I183 PolarHBondContact O-N 3.47Å; A181-I183 VanDerWaalsContact C-N 3.34Å; A181-I183 PolarHBondContact O-N 3.34Å; I183-L185 PolarHBondContact O-N 2.9Å; I183-I186 PolarHBondContact O-N 3.41Å; I183-V187 PolarHBondContact O-N 3.29Å
184I93.5Very high91.2Very high28 Ų2857 Ų5714%0.14428%0.283CS..Hα-helixtrans-65.5-38.4-177.6-64.5-60.1000112.3K180 A181 I186 V187 L192 F194 F466 W469K180-I184 VanDerWaalsContact O-CG1 3.32Å; K180-I184 WeakPolarHBondContact O-CG1 3.33Å; K180-I184 PolarHBondContact O-N 2.92Å; A181-I184 PolarHBondContact O-N 3.07Å; I184-I186 PolarHBondContact O-N 3.41Å; I184-V187 WeakPolarHBondContact O-CB 3.26Å; I184-V187 PolarHBondContact O-N 2.83Å; I184-V187 VanDerWaalsContact O-N 3.1Å; I184-L192 HydrophobicContact CD1-CD1 4.27Å; I184-L192 HydrophobicContact CG2-CD1 3.98Å; I184-F194 HydrophobicContact CG2-CE2 3.9Å; I184-F194 HydrophobicContact CG2-CZ 4.3Å; I184-F466 HydrophobicContact CG2-CE2 4.21Å; I184-W469 HydrophobicContact CB-CH2 4.48Å; I184-W469 HydrophobicContact CB-CZ3 4.43Å; I184-W469 HydrophobicContact CD1-CH2 3.81Å; I184-W469 HydrophobicContact CG1-CH2 3.86Å; I184-W469 HydrophobicContact CG1-CZ3 4.16Å; I184-W469 HydrophobicContact CG2-CH2 3.84Å; I184-W469 HydrophobicContact CG2-CZ3 3.66Å
185L92Very high90.7Very high8 Ų856.9 Ų56.94%0.04228%0.284CS..Hα-helixtrans-69.6-13.4178.9-70.9171.2000113.6A181 M182 I183 L196 K228 L231 A232 F466A181-L185 WeakPolarHBondContact O-CB 3.41Å; A181-L185 VanDerWaalsContact O-CG 3.24Å; A181-L185 WeakPolarHBondContact O-CG 3.45Å; A181-L185 PolarHBondContact O-N 2.67Å; M182-L185 PolarHBondContact O-N 3.27Å; I183-L185 PolarHBondContact O-N 2.9Å; L185-L196 HydrophobicContact CD2-CD2 3.58Å; L185-K228 HydrophobicContact CB-CD 4.4Å; L185-K228 HydrophobicContact CD1-CB 4.43Å; L185-K228 VanDerWaalsContact CD1-O 3.32Å; L185-K228 WeakPolarHBondContact CD1-O 3.49Å; L185-K228 WeakPolarHBondContact O-CE 3.41Å; L185-K228 PolarHBondContact O-NZ 3.46Å; L185-L231 HydrophobicContact CD1-CB 4.23Å; L185-L231 HydrophobicContact CD1-CD2 4.42Å; L185-L231 HydrophobicContact CD1-CG 4.31Å; L185-L231 HydrophobicContact CD2-CD2 3.6Å; L185-L231 HydrophobicContact CD2-CG 4.27Å; L185-A232 HydrophobicContact CD1-CB 3.99Å; L185-F466 HydrophobicContact CD2-CD2 4.44Å; L185-F466 HydrophobicContact CD2-CE1 4.31Å; L185-F466 HydrophobicContact CD2-CE2 3.76Å; L185-F466 HydrophobicContact CD2-CZ 3.67Å; L185-F466 HydrophobicContact CG-CE2 4.4Å; L185-F466 HydrophobicContact CG-CZ 4.16Å
186I89.9Confident90.4Very high121 Ų12150.8 Ų50.862%0.62126%0.258SS*.Hα-helixtrans-88.5-25.1172.6-66.6165.4000111.3M182 I183 I184 T188M182-I186 WeakPolarHBondContact O-CD1 3.05Å; M182-I186 VanDerWaalsContact O-CG1 3.28Å; M182-I186 WeakPolarHBondContact O-CG1 3.24Å; M182-I186 PolarHBondContact O-N 2.9Å; I183-I186 PolarHBondContact O-N 3.41Å; I184-I186 PolarHBondContact O-N 3.41Å; I186-T188 PolarHBondContact O-N 3.24Å
187V87.9Confident90Very high54 Ų5450.5 Ų50.533%0.32726%0.257SS..SBendtrans-60.5136.9179.2178.60000110.1I183 I184 L192I183-V187 PolarHBondContact O-N 3.29Å; I184-V187 WeakPolarHBondContact O-CB 3.26Å; I184-V187 PolarHBondContact O-N 2.83Å; I184-V187 VanDerWaalsContact O-N 3.1Å; V187-L192 HydrophobicContact CB-CD1 4.08Å; V187-L192 HydrophobicContact CG1-CB 4.47Å; V187-L192 HydrophobicContact CG1-CD1 3.83Å; V187-L192 HydrophobicContact CG1-CG 4.07Å; V187-L192 HydrophobicContact CG2-CD1 4.47Å
188T82Confident89.6Confident70 Ų7054 Ų5443%0.42928%0.279SS..  trans-73.6151.8-178.356.80000112I186 N190 Y191 L192I186-T188 PolarHBondContact O-N 3.24Å; T188-N190 PolarHBondContact O-N 3.33Å; T188-Y191 PolarHBondContact O-N 2.9Å; T188-Y191 VanDerWaalsContact O-N 3.08Å; T188-Y191 WeakPolarHBondContact OG1-CD2 3.41Å; T188-L192 PolarHBondContact O-N 3.41Å
189E82.8Confident89.1Confident43 Ų4351.3 Ų51.320%0.20127%0.267CS..THydrogen-bonded Turntrans-65.6-7.6178.9-59.2-164.2156.300114Y191 L192 G195 L196 E197 K285E189-Y191 VanDerWaalsContact C-N 3.3Å; E189-L192 WeakPolarHBondContact CA-O 3.27Å; E189-G195 VanDerWaalsContact OE1-C 3.3Å; E189-G195 WeakPolarHBondContact OE1-CA 3.28Å; E189-L196 PolarHBondContact OE1-N 3.46Å; E189-E197 HydrophobicContact CG-CG 4.27Å; E189-E197 WeakPolarHBondContact OE1-CB 3.49Å; E189-E197 PolarHBondContact OE1-N 3.2Å; E189-K285 VanDerWaalsContact O-CE 3.24Å; E189-K285 WeakPolarHBondContact O-CE 3.34Å; E189-K285 PolarHBondContact O-NZ 3.38Å
190N81.4Confident88.8Confident120 Ų12049.4 Ų49.464%0.64225%0.254SS*.THydrogen-bonded Turntrans-71.2-26.4173.2-66.4-20000112.3T188 K285T188-N190 PolarHBondContact O-N 3.33Å; N190-K285 WeakPolarHBondContact O-CD 3.48Å
191Y84Confident88.5Confident145 Ų14549.8 Ų49.857%0.56926%0.264SS*.THydrogen-bonded Turntrans-101.7-43.1177.1-63.9-78.5000112T188 E189 K285 P286T188-Y191 PolarHBondContact O-N 2.9Å; T188-Y191 VanDerWaalsContact O-N 3.08Å; T188-Y191 WeakPolarHBondContact OG1-CD2 3.41Å; E189-Y191 VanDerWaalsContact C-N 3.3Å; Y191-K285 PolarHBondContact O-N 2.82Å; Y191-P286 HydrophobicContact CD1-CG 4.45Å
192L86.1Confident88.2Confident16 Ų1652.6 Ų52.68%0.08428%0.279CS..BIsolated β-bridgetrans-116.5112.7-178.3-68.4174.2000110.8I184 V187 T188 E189 F194 V284 W469I184-L192 HydrophobicContact CD1-CD1 4.27Å; I184-L192 HydrophobicContact CG2-CD1 3.98Å; V187-L192 HydrophobicContact CB-CD1 4.08Å; V187-L192 HydrophobicContact CG1-CB 4.47Å; V187-L192 HydrophobicContact CG1-CD1 3.83Å; V187-L192 HydrophobicContact CG1-CG 4.07Å; V187-L192 HydrophobicContact CG2-CD1 4.47Å; T188-L192 PolarHBondContact O-N 3.41Å; E189-L192 WeakPolarHBondContact CA-O 3.27Å; L192-F194 VanDerWaalsContact C-N 3.35Å; L192-F194 HydrophobicContact CB-CD2 4.02Å; L192-F194 HydrophobicContact CB-CE1 4.49Å; L192-F194 HydrophobicContact CB-CE2 3.52Å; L192-F194 HydrophobicContact CB-CZ 3.78Å; L192-F194 HydrophobicContact CD1-CE2 3.72Å; L192-F194 HydrophobicContact CD1-CZ 3.88Å; L192-F194 HydrophobicContact CD2-CZ 4.22Å; L192-F194 HydrophobicContact CG-CE2 4.16Å; L192-F194 HydrophobicContact CG-CZ 4.18Å; L192-F194 PolarHBondContact O-N 2.93Å; L192-V284 HydrophobicContact CD2-CG2 3.87Å; L192-W469 HydrophobicContact CD2-CZ2 4.46Å
193E86.6Confident88Confident30 Ų3051.2 Ų51.214%0.1427%0.272CS..  trans-84.572.2-174.6-164.5173.3-139.800112.6W283 K285 K289 R314E193-W283 PolarHBondContact N-O 3.33Å; E193-W283 VanDerWaalsContact O-CD1 3.27Å; E193-K285 HydrophobicContact CB-CD 4.22Å; E193-K285 VanDerWaalsContact CB-CE 3.43Å; E193-K285 HydrophobicContact CB-CG 3.85Å; E193-K285 VanDerWaalsContact CD-CE 3.48Å; E193-K285 WeakPolarHBondContact OE1-CE 3.21Å; E193-K289 WeakPolarHBondContact OE1-CD 3.3Å; E193-K289 IonicContact OE1-NZ 2.88Å; E193-K289 PolarHBondContact OE1-NZ 3.48Å; E193-K289 WeakPolarHBondContact OE2-CD 3.39Å; E193-K289 IonicContact OE2-NZ 2.76Å; E193-R314 IonicContact OE2-CZ 3.22Å; E193-R314 IonicContact OE2-NH1 2.63Å; E193-R314 PolarHBondContact OE2-NH1 3.04Å; E193-R314 IonicContact OE2-NH2 3.6Å; E193-R314 PolarHBondContact OE2-NH2 2.99Å
194F87.8Confident87.8Confident18 Ų1847.5 Ų47.58%0.07925%0.254CS..  trans-86.6-40.6174.6-56.8-48.2000112.6I184 L192 L196 W283 G462 S465 F466 W469I184-F194 HydrophobicContact CG2-CE2 3.9Å; I184-F194 HydrophobicContact CG2-CZ 4.3Å; L192-F194 VanDerWaalsContact C-N 3.35Å; L192-F194 HydrophobicContact CB-CD2 4.02Å; L192-F194 HydrophobicContact CB-CE1 4.49Å; L192-F194 HydrophobicContact CB-CE2 3.52Å; L192-F194 HydrophobicContact CB-CZ 3.78Å; L192-F194 HydrophobicContact CD1-CE2 3.72Å; L192-F194 HydrophobicContact CD1-CZ 3.88Å; L192-F194 HydrophobicContact CD2-CZ 4.22Å; L192-F194 HydrophobicContact CG-CE2 4.16Å; L192-F194 HydrophobicContact CG-CZ 4.18Å; L192-F194 PolarHBondContact O-N 2.93Å; F194-L196 HydrophobicContact CB-CB 4.19Å; F194-W283 AromaticContact CD1-CD1 3.72Å; F194-W283 HydrophobicContact CD1-CG 4.46Å; F194-W283 HydrophobicContact CE1-CB 4.15Å; F194-W283 AromaticContact CE1-CD1 3.91Å; F194-W283 HydrophobicContact CE1-CG 4.23Å; F194-G462 WeakPolarHBondContact O-CA 3.36Å; F194-S465 PolarHBondContact O-OG 2.82Å; F194-F466 HydrophobicContact CB-CB 4.38Å; F194-F466 HydrophobicContact CD1-CB 4.38Å; F194-F466 HydrophobicContact CD1-CD2 4.39Å; F194-F466 AromaticContact CD2-CD2 3.95Å; F194-F466 HydrophobicContact CD2-CD2 3.95Å; F194-F466 HydrophobicContact CE1-CD2 4.47Å; F194-F466 AromaticContact CE2-CD2 3.99Å; F194-F466 HydrophobicContact CE2-CD2 3.99Å; F194-F466 HydrophobicContact CE2-CE2 4.44Å; F194-F466 HydrophobicContact CG-CB 4.31Å; F194-F466 HydrophobicContact CG-CD2 4.15Å; F194-F466 HydrophobicContact CZ-CD2 4.27Å; F194-W469 HydrophobicContact CD1-CB 4.5Å; F194-W469 HydrophobicContact CE1-CB 3.74Å; F194-W469 AromaticContact CE1-CD1 3.99Å; F194-W469 AromaticContact CE1-CD2 3.66Å; F194-W469 HydrophobicContact CE1-CD2 3.66Å; F194-W469 HydrophobicContact CE1-CE3 4.08Å; F194-W469 AromaticContact CE1-CG 3.5Å; F194-W469 HydrophobicContact CE1-CG 3.5Å; F194-W469 AromaticContact CZ-CD2 3.57Å; F194-W469 HydrophobicContact CZ-CD2 3.57Å; F194-W469 AromaticContact CZ-CE2 3.92Å; F194-W469 AromaticContact CZ-CE3 3.69Å; F194-W469 HydrophobicContact CZ-CE3 3.69Å; F194-W469 AromaticContact CZ-CG 3.96Å; F194-W469 HydrophobicContact CZ-CG 3.96Å; F194-W469 HydrophobicContact CZ-CH2 4.49Å; F194-W469 HydrophobicContact CZ-CZ2 4.36Å; F194-W469 HydrophobicContact CZ-CZ3 4.18Å
195G86.3Confident87.5Confident18 Ų1850.5 Ų50.519%0.18627%0.271CS..  trans75.228.9-169.100000112.6E189 T198 G199 G462E189-G195 VanDerWaalsContact OE1-C 3.3Å; E189-G195 WeakPolarHBondContact OE1-CA 3.28Å; G195-T198 WeakPolarHBondContact CA-OG1 3.3Å; G195-T198 PolarHBondContact O-OG1 3.32Å; G195-G199 PolarHBondContact O-N 3.24Å; G195-G199 VanDerWaalsContact O-N 3.12Å; G195-G462 WeakPolarHBondContact O-CA 3.41Å
196L89.2Confident87.3Confident11 Ų1151.3 Ų51.36%0.05828%0.277CS..Hα-helixtrans-82.4-38.7-175.2-173.770.6000111.7L185 E189 F194 F200 F227 L231 L463L185-L196 HydrophobicContact CD2-CD2 3.58Å; E189-L196 PolarHBondContact OE1-N 3.46Å; F194-L196 HydrophobicContact CB-CB 4.19Å; L196-F200 VanDerWaalsContact O-CB 3.23Å; L196-F200 WeakPolarHBondContact O-CB 3.46Å; L196-F200 PolarHBondContact O-N 2.8Å; L196-F227 HydrophobicContact CD1-CE1 3.77Å; L196-F227 HydrophobicContact CD1-CZ 3.77Å; L196-F227 HydrophobicContact CD2-CE1 4.17Å; L196-F227 HydrophobicContact CG-CE1 3.87Å; L196-F227 HydrophobicContact CG-CZ 4.38Å; L196-L231 HydrophobicContact CD1-CD2 4.05Å; L196-L231 HydrophobicContact CD2-CD2 3.54Å; L196-L231 HydrophobicContact CG-CD2 4.42Å; L196-L463 HydrophobicContact CD1-CD2 3.93Å
197E88.8Confident87.1Confident69 Ų6945.9 Ų45.932%0.32225%0.251SS..Hα-helixtrans-71.6-43177.8-58.1-146.5149.200111.2E189 F200 A201 K224 K228E189-E197 HydrophobicContact CG-CG 4.27Å; E189-E197 WeakPolarHBondContact OE1-CB 3.49Å; E189-E197 PolarHBondContact OE1-N 3.2Å; E197-F200 PolarHBondContact O-N 3.42Å; E197-A201 WeakPolarHBondContact O-CB 3.22Å; E197-A201 PolarHBondContact O-N 3.12Å; E197-K224 WeakPolarHBondContact OE1-CE 3.42Å; E197-K224 IonicContact OE1-NZ 2.91Å; E197-K224 PolarHBondContact OE1-NZ 3.39Å; E197-K224 IonicContact OE2-NZ 2.85Å; E197-K224 PolarHBondContact OE2-NZ 2.76Å; E197-K228 IonicContact OE1-NZ 3.94Å; E197-K228 PolarHBondContact OE1-NZ 2.85Å
198T88.6Confident86.9Confident73 Ų7346.7 Ų46.745%0.44825%0.25SS..Hα-helixtrans-63.6-44.3174.146.50000111.7G195 A201 N202G195-T198 WeakPolarHBondContact CA-OG1 3.3Å; G195-T198 PolarHBondContact O-OG1 3.32Å; T198-A201 PolarHBondContact O-N 3.38Å; T198-N202 WeakPolarHBondContact O-CB 3.44Å; T198-N202 PolarHBondContact O-N 2.87Å; T198-N202 VanDerWaalsContact O-N 3.09Å
199G88.4Confident87Confident0 Ų048.8 Ų48.80%026%0.255CS..Hα-helixtrans-62.3-41.3174.200000113.3G195 F203G195-G199 PolarHBondContact O-N 3.24Å; G195-G199 VanDerWaalsContact O-N 3.12Å; G199-F203 WeakPolarHBondContact O-CB 3.38Å; G199-F203 PolarHBondContact O-N 2.9Å
200F90.1Very high87.1Confident19 Ų1949.6 Ų49.68%0.08326%0.259CS..Hα-helixtrans-67.6-41.7176.9175.6-98.9000112.7L196 E197 F203 S204 I222 K224 F227L196-F200 VanDerWaalsContact O-CB 3.23Å; L196-F200 WeakPolarHBondContact O-CB 3.46Å; L196-F200 PolarHBondContact O-N 2.8Å; E197-F200 PolarHBondContact O-N 3.42Å; F200-F203 HydrophobicContact CD2-CD1 4.46Å; F200-F203 PolarHBondContact O-N 3.47Å; F200-S204 WeakPolarHBondContact O-CB 3.23Å; F200-S204 PolarHBondContact O-N 2.95Å; F200-I222 WeakPolarHBondContact CZ-O 3.49Å; F200-K224 HydrophobicContact CD1-CB 4.47Å; F200-K224 HydrophobicContact CD1-CG 4.37Å; F200-K224 HydrophobicContact CE1-CB 3.81Å; F200-K224 HydrophobicContact CE1-CG 4.19Å; F200-K224 HydrophobicContact CZ-CB 4.33Å; F200-F227 HydrophobicContact CB-CD1 4.4Å; F200-F227 HydrophobicContact CB-CE1 4.17Å; F200-F227 HydrophobicContact CD2-CB 3.9Å; F200-F227 AromaticContact CD2-CD1 3.69Å; F200-F227 HydrophobicContact CD2-CD1 3.69Å; F200-F227 AromaticContact CD2-CD2 3.71Å; F200-F227 HydrophobicContact CD2-CD2 3.71Å; F200-F227 HydrophobicContact CD2-CE1 4.09Å; F200-F227 HydrophobicContact CD2-CE2 4.11Å; F200-F227 AromaticContact CD2-CG 3.48Å; F200-F227 HydrophobicContact CD2-CG 3.48Å; F200-F227 VanDerWaalsContact CD2-CG 3.48Å; F200-F227 HydrophobicContact CD2-CZ 4.28Å; F200-F227 HydrophobicContact CE2-CB 3.56Å; F200-F227 HydrophobicContact CE2-CD1 4.26Å; F200-F227 HydrophobicContact CE2-CD2 4.01Å; F200-F227 AromaticContact CE2-CG 3.69Å; F200-F227 HydrophobicContact CE2-CG 3.69Å; F200-F227 HydrophobicContact CG-CD1 4.12Å; F200-F227 HydrophobicContact CG-CE1 4.36Å; F200-F227 HydrophobicContact CG-CG 4.34Å; F200-F227 HydrophobicContact CZ-CB 4.24Å
201A89.6Confident87.1Confident45 Ų4545.6 Ų45.637%0.37224%0.237SC..Hα-helixtrans-60-48.5176.400000110.8E197 T198 F203 S204 D205E197-A201 WeakPolarHBondContact O-CB 3.22Å; E197-A201 PolarHBondContact O-N 3.12Å; T198-A201 PolarHBondContact O-N 3.38Å; A201-F203 VanDerWaalsContact C-N 3.33Å; A201-F203 PolarHBondContact O-N 2.99Å; A201-S204 PolarHBondContact O-N 3.1Å; A201-D205 PolarHBondContact O-N 3.37Å
202N89.6Confident87Confident58 Ų5844.1 Ų44.131%0.3124%0.235SC..Hα-helixtrans-60.5-41.2176.8-177.7-82.8000112.6T198 S206 S456 L458T198-N202 WeakPolarHBondContact O-CB 3.44Å; T198-N202 PolarHBondContact O-N 2.87Å; T198-N202 VanDerWaalsContact O-N 3.09Å; N202-S206 VanDerWaalsContact O-CB 3.26Å; N202-S206 WeakPolarHBondContact O-CB 3.39Å; N202-S206 PolarHBondContact O-N 2.86Å; N202-S206 PolarHBondContact O-OG 3.23Å; N202-S456 WeakPolarHBondContact OD1-CB 3.23Å; N202-S456 PolarHBondContact OD1-OG 3.47Å; N202-L458 HydrophobicContact CB-CD2 4.03Å
203F89.6Confident86.8Confident27 Ų2751 Ų5112%0.11827%0.267CS..Hα-helixtrans-62.9-45.6174.2166.9-99.9000112.2G199 F200 A201 S206 A207 P221 V454 F455 L459G199-F203 WeakPolarHBondContact O-CB 3.38Å; G199-F203 PolarHBondContact O-N 2.9Å; F200-F203 HydrophobicContact CD2-CD1 4.46Å; F200-F203 PolarHBondContact O-N 3.47Å; A201-F203 VanDerWaalsContact C-N 3.33Å; A201-F203 PolarHBondContact O-N 2.99Å; F203-S206 PolarHBondContact O-N 3.06Å; F203-A207 HydrophobicContact CZ-CB 4.5Å; F203-A207 WeakPolarHBondContact O-CB 3.36Å; F203-A207 PolarHBondContact O-N 2.82Å; F203-P221 HydrophobicContact CE1-CG 4.34Å; F203-V454 HydrophobicContact CD2-CG1 3.81Å; F203-V454 WeakPolarHBondContact CD2-O 3.42Å; F203-V454 HydrophobicContact CE2-CG1 3.52Å; F203-F455 HydrophobicContact CE2-CE1 4.28Å; F203-F455 HydrophobicContact CE2-CZ 4.45Å; F203-L459 HydrophobicContact CB-CB 4.48Å; F203-L459 HydrophobicContact CB-CD1 4.06Å; F203-L459 HydrophobicContact CB-CD2 4.03Å; F203-L459 HydrophobicContact CB-CG 4.41Å; F203-L459 HydrophobicContact CD2-CD2 3.67Å; F203-L459 HydrophobicContact CE2-CD2 4.4Å; F203-L459 HydrophobicContact CG-CD1 4.48Å; F203-L459 HydrophobicContact CG-CD2 3.97Å
204S88.9Confident86.5Confident24 Ų2455.5 Ų55.517%0.16829%0.287CS..Hα-helixtrans-61.5-46.3-179.8-171.90000111.1F200 A201 A207 Q208F200-S204 WeakPolarHBondContact O-CB 3.23Å; F200-S204 PolarHBondContact O-N 2.95Å; A201-S204 PolarHBondContact O-N 3.1Å; S204-A207 PolarHBondContact O-N 2.98Å; S204-Q208 WeakPolarHBondContact O-CB 3.36Å; S204-Q208 PolarHBondContact O-N 3.35Å
205D87.8Confident86Confident92 Ų9257.7 Ų57.749%0.49232%0.316SS..Hα-helixtrans-64.5-46.5178.9-67.2-7.8000111A201 A207 Q208 Q209A201-D205 PolarHBondContact O-N 3.37Å; D205-A207 PolarHBondContact O-N 3.32Å; D205-Q208 PolarHBondContact O-N 3.24Å; D205-Q209 WeakPolarHBondContact O-CG 3.43Å; D205-Q209 PolarHBondContact O-N 2.89Å
206S87.2Confident85.5Confident25 Ų2561.7 Ų61.718%0.17533%0.332CS..Hα-helixtrans-65.9-37.9179.7-55.70000112.2N202 F203 F210N202-S206 VanDerWaalsContact O-CB 3.26Å; N202-S206 WeakPolarHBondContact O-CB 3.39Å; N202-S206 PolarHBondContact O-N 2.86Å; N202-S206 PolarHBondContact O-OG 3.23Å; F203-S206 PolarHBondContact O-N 3.06Å; S206-F210 WeakPolarHBondContact O-CB 3.36Å; S206-F210 PolarHBondContact O-N 3.42Å
207A85.3Confident84.1Confident7 Ų771 Ų716%0.05838%0.375CS..Hα-helixtrans-70.6-36.2176.700000112.1F203 S204 D205 F210 L211 P221 V454F203-A207 HydrophobicContact CZ-CB 4.5Å; F203-A207 WeakPolarHBondContact O-CB 3.36Å; F203-A207 PolarHBondContact O-N 2.82Å; S204-A207 PolarHBondContact O-N 2.98Å; D205-A207 PolarHBondContact O-N 3.32Å; A207-F210 PolarHBondContact O-N 3.21Å; A207-L211 WeakPolarHBondContact O-CB 3.19Å; A207-L211 WeakPolarHBondContact O-CD1 3.48Å; A207-L211 WeakPolarHBondContact O-CG 3.34Å; A207-L211 PolarHBondContact O-N 3.42Å; A207-P221 HydrophobicContact CB-CG 3.65Å; A207-V454 HydrophobicContact CB-CG1 3.95Å
208Q85.6Confident82.8Confident70 Ų7070.6 Ų70.633%0.32738%0.38SS..Hα-helixtrans-63.4-48.5173.9-177.7177.8-21.500110.7S204 D205 F210 L211 E212S204-Q208 WeakPolarHBondContact O-CB 3.36Å; S204-Q208 PolarHBondContact O-N 3.35Å; D205-Q208 PolarHBondContact O-N 3.24Å; Q208-F210 VanDerWaalsContact C-N 3.29Å; Q208-F210 PolarHBondContact O-N 3.01Å; Q208-L211 PolarHBondContact O-N 3.41Å; Q208-L211 VanDerWaalsContact O-N 3.13Å; Q208-E212 HydrophobicContact CG-CG 4.48Å; Q208-E212 WeakPolarHBondContact CG-OE1 3.42Å; Q208-E212 PolarHBondContact NE2-OE1 3.33Å; Q208-E212 WeakPolarHBondContact O-CG 3.32Å; Q208-E212 PolarHBondContact O-N 3.26Å
209Q84Confident81.4Confident114 Ų11477 Ų7753%0.53341%0.405SS..Hα-helixtrans-58-41.9175.4-69.9174.611.100111.8D205 E212 H213D205-Q209 WeakPolarHBondContact O-CG 3.43Å; D205-Q209 PolarHBondContact O-N 2.89Å; Q209-E212 PolarHBondContact O-N 3.28Å; Q209-H213 PolarHBondContact O-CD2 2.96Å; Q209-H213 PolarHBondContact O-N 3.32Å
210F83.2Confident80.1Confident61 Ų6177.9 Ų77.927%0.26841%0.414SS..Hα-helixtrans-62.8-42.3175.8-179.9-96.5000112.6S206 A207 Q208 H213 Q214 V454S206-F210 WeakPolarHBondContact O-CB 3.36Å; S206-F210 PolarHBondContact O-N 3.42Å; A207-F210 PolarHBondContact O-N 3.21Å; Q208-F210 VanDerWaalsContact C-N 3.29Å; Q208-F210 PolarHBondContact O-N 3.01Å; F210-H213 PolarHBondContact O-N 3.22Å; F210-Q214 HydrophobicContact CD1-CG 4.45Å; F210-Q214 HydrophobicContact CE1-CG 4.05Å; F210-Q214 HydrophobicContact CZ-CG 4.15Å; F210-Q214 WeakPolarHBondContact O-CG 3.36Å; F210-Q214 PolarHBondContact O-N 3.34Å; F210-Q214 VanDerWaalsContact O-N 3.16Å; F210-V454 HydrophobicContact CB-CG2 3.59Å; F210-V454 HydrophobicContact CD1-CG2 4.39Å; F210-V454 HydrophobicContact CD2-CG2 4.35Å; F210-V454 HydrophobicContact CG-CG2 3.86Å
211L82Confident79.1Confident36 Ų3679.4 Ų79.419%0.18843%0.426CS..Hα-helixtrans-66.1-41.4177.5-77.7161.7000112.1A207 Q208 H213 Q214 G215 L216 P221A207-L211 WeakPolarHBondContact O-CB 3.19Å; A207-L211 WeakPolarHBondContact O-CD1 3.48Å; A207-L211 WeakPolarHBondContact O-CG 3.34Å; A207-L211 PolarHBondContact O-N 3.42Å; Q208-L211 PolarHBondContact O-N 3.41Å; Q208-L211 VanDerWaalsContact O-N 3.13Å; L211-H213 VanDerWaalsContact C-N 3.33Å; L211-H213 PolarHBondContact O-N 2.99Å; L211-Q214 CarbonylContact O-C 3.49Å; L211-Q214 WeakPolarHBondContact O-CA 3.3Å; L211-Q214 PolarHBondContact O-N 3.28Å; L211-G215 PolarHBondContact O-N 3.01Å; L211-L216 HydrophobicContact CD2-CB 4.1Å; L211-L216 HydrophobicContact CD2-CD1 3.78Å; L211-L216 PolarHBondContact O-N 2.93Å; L211-P221 HydrophobicContact CD1-CB 4.2Å
212E82.8Confident78.8Confident113 Ų11380.4 Ų80.453%0.52842%0.424SS..Hα-helixtrans-59.8-43.8174.3-74.3174-171.700110.9Q208 Q209 Q214 G215Q208-E212 HydrophobicContact CG-CG 4.48Å; Q208-E212 WeakPolarHBondContact CG-OE1 3.42Å; Q208-E212 PolarHBondContact NE2-OE1 3.33Å; Q208-E212 WeakPolarHBondContact O-CG 3.32Å; Q208-E212 PolarHBondContact O-N 3.26Å; Q209-E212 PolarHBondContact O-N 3.28Å; E212-Q214 PolarHBondContact O-N 3.21Å; E212-G215 PolarHBondContact O-N 3.3Å
213H82Confident78.6Confident161 Ų16180.6 Ų80.675%0.74543%0.43SS*.Hα-helixtrans-63.5-25.2174-79.8-60.3000114Q209 F210 L211 G215Q209-H213 PolarHBondContact O-CD2 2.96Å; Q209-H213 PolarHBondContact O-N 3.32Å; F210-H213 PolarHBondContact O-N 3.22Å; L211-H213 VanDerWaalsContact C-N 3.33Å; L211-H213 PolarHBondContact O-N 2.99Å; H213-G215 VanDerWaalsContact C-N 3.32Å
214Q80.8Confident78.6Confident124 Ų12483.6 Ų83.658%0.57944%0.443SS*.THydrogen-bonded Turntrans-88.63.3174.1-63.1-61.7-48.800113F210 L211 E212 L216F210-Q214 HydrophobicContact CD1-CG 4.45Å; F210-Q214 HydrophobicContact CE1-CG 4.05Å; F210-Q214 HydrophobicContact CZ-CG 4.15Å; F210-Q214 WeakPolarHBondContact O-CG 3.36Å; F210-Q214 PolarHBondContact O-N 3.34Å; F210-Q214 VanDerWaalsContact O-N 3.16Å; L211-Q214 CarbonylContact O-C 3.49Å; L211-Q214 WeakPolarHBondContact O-CA 3.3Å; L211-Q214 PolarHBondContact O-N 3.28Å; E212-Q214 PolarHBondContact O-N 3.21Å; Q214-L216 VanDerWaalsContact C-N 3.31Å; Q214-L216 PolarHBondContact O-N 3.45Å
215G76.8Confident78.6Confident65 Ų6588.4 Ų88.467%0.6747%0.466SS*.THydrogen-bonded Turntrans74.517.9179.600000114.3L211 E212 H213L211-G215 PolarHBondContact O-N 3.01Å; E212-G215 PolarHBondContact O-N 3.3Å; H213-G215 VanDerWaalsContact C-N 3.32Å
216L74.9Confident78.7Confident102 Ų10287 Ų8753%0.53446%0.461SS..  trans-98.8102.2176.7-64.3176000109.5L211 Q214 S218L211-L216 HydrophobicContact CD2-CB 4.1Å; L211-L216 HydrophobicContact CD2-CD1 3.78Å; L211-L216 PolarHBondContact O-N 2.93Å; Q214-L216 VanDerWaalsContact C-N 3.31Å; Q214-L216 PolarHBondContact O-N 3.45Å; L216-S218 PolarHBondContact O-N 3.49Å
217E61Low78.9Confident205 Ų20587.3 Ų87.396%0.95846%0.459SS*.  trans-72.496.5169.7-71.2-169.5173.400109.6
218S61.6Low79.2Confident62 Ų6288.6 Ų88.643%0.43446%0.463SS..  trans-125.8142.5175.9-169.20000110.1L216 G220L216-S218 PolarHBondContact O-N 3.49Å; S218-G220 PolarHBondContact O-N 3.11Å
219Q58.3Low79.6Confident208 Ų20889 Ų8997%0.97247%0.467SS*.SBendtrans-72.639.5179.2-68.5-170-22.700113.6
220G60.9Low80.1Confident17 Ų1788.2 Ų88.218%0.17547%0.466CS..  trans85.5150.2-172.500000112.8S218S218-G220 PolarHBondContact O-N 3.11Å
221P69.9Low80.7Confident52 Ų5285.7 Ų85.734%0.33846%0.455SS..SBendtrans-75.4-33.1-166.830.1-38.5000114.4F203 A207 L211F203-P221 HydrophobicContact CE1-CG 4.34Å; A207-P221 HydrophobicContact CB-CG 3.65Å; L211-P221 HydrophobicContact CD1-CB 4.2Å
222I82Confident81.4Confident66 Ų6684 Ų8434%0.33845%0.446SS..SBendtrans-150.4136.8-173.2-56.2178.8000109.9F200 T226 F227F200-I222 WeakPolarHBondContact CZ-O 3.49Å; I222-T226 HydrophobicContact CG2-CG2 3.92Å; I222-F227 HydrophobicContact CG2-CB 4.35Å
223S87.1Confident82.1Confident61 Ų6183 Ų8343%0.42744%0.444SS..  trans-72.4149.4174.386.60000112.5L225 T226 F227S223-L225 PolarHBondContact O-N 3.47Å; S223-T226 PolarHBondContact O-N 2.98Å; S223-T226 WeakPolarHBondContact OG-CB 3.48Å; S223-T226 PolarHBondContact OG-N 3.35Å; S223-T226 PolarHBondContact OG-OG1 2.88Å; S223-F227 PolarHBondContact O-N 3.08Å
224K87.8Confident82.7Confident90 Ų9078.9 Ų78.939%0.39143%0.427SS..Hα-helixtrans-55.1-36.4176-172.8174.6-178.9176.60112.4E197 F200 K228E197-K224 WeakPolarHBondContact OE1-CE 3.42Å; E197-K224 IonicContact OE1-NZ 2.91Å; E197-K224 PolarHBondContact OE1-NZ 3.39Å; E197-K224 IonicContact OE2-NZ 2.85Å; E197-K224 PolarHBondContact OE2-NZ 2.76Å; F200-K224 HydrophobicContact CD1-CB 4.47Å; F200-K224 HydrophobicContact CD1-CG 4.37Å; F200-K224 HydrophobicContact CE1-CB 3.81Å; F200-K224 HydrophobicContact CE1-CG 4.19Å; F200-K224 HydrophobicContact CZ-CB 4.33Å; K224-K228 WeakPolarHBondContact O-CG 3.33Å; K224-K228 PolarHBondContact O-N 2.94Å; K224-K228 VanDerWaalsContact O-N 3.08Å
225L88.9Confident83.5Confident125 Ų12573 Ų7365%0.65440%0.399SS*.Hα-helixtrans-66.9-47.1176.4-179.567.5000111.5S223 F227 K228 L229S223-L225 PolarHBondContact O-N 3.47Å; L225-F227 VanDerWaalsContact C-N 3.31Å; L225-F227 PolarHBondContact O-N 3.31Å; L225-K228 PolarHBondContact O-N 3.33Å; L225-L229 WeakPolarHBondContact O-CB 3.44Å; L225-L229 PolarHBondContact O-N 3.31Å
226T90.7Very high84.5Confident63 Ų6370.7 Ų70.739%0.38737%0.374SS..Hα-helixtrans-60.3-42.6178.2-540000111I222 S223 L229 I230I222-T226 HydrophobicContact CG2-CG2 3.92Å; S223-T226 PolarHBondContact O-N 2.98Å; S223-T226 WeakPolarHBondContact OG-CB 3.48Å; S223-T226 PolarHBondContact OG-N 3.35Å; S223-T226 PolarHBondContact OG-OG1 2.88Å; T226-L229 PolarHBondContact O-N 3.29Å; T226-I230 HydrophobicContact CG2-CD1 3.99Å; T226-I230 WeakPolarHBondContact O-CG1 3.46Å; T226-I230 PolarHBondContact O-N 3.35Å
227F91.1Very high85.5Confident32 Ų3269.9 Ų69.914%0.1437%0.369CS..Hα-helixtrans-59.2-49.9175176.2-101000112L196 F200 I222 S223 L225 L229 I230 L231 L463L196-F227 HydrophobicContact CD1-CE1 3.77Å; L196-F227 HydrophobicContact CD1-CZ 3.77Å; L196-F227 HydrophobicContact CD2-CE1 4.17Å; L196-F227 HydrophobicContact CG-CE1 3.87Å; L196-F227 HydrophobicContact CG-CZ 4.38Å; F200-F227 HydrophobicContact CB-CD1 4.4Å; F200-F227 HydrophobicContact CB-CE1 4.17Å; F200-F227 HydrophobicContact CD2-CB 3.9Å; F200-F227 AromaticContact CD2-CD1 3.69Å; F200-F227 HydrophobicContact CD2-CD1 3.69Å; F200-F227 AromaticContact CD2-CD2 3.71Å; F200-F227 HydrophobicContact CD2-CD2 3.71Å; F200-F227 HydrophobicContact CD2-CE1 4.09Å; F200-F227 HydrophobicContact CD2-CE2 4.11Å; F200-F227 AromaticContact CD2-CG 3.48Å; F200-F227 HydrophobicContact CD2-CG 3.48Å; F200-F227 VanDerWaalsContact CD2-CG 3.48Å; F200-F227 HydrophobicContact CD2-CZ 4.28Å; F200-F227 HydrophobicContact CE2-CB 3.56Å; F200-F227 HydrophobicContact CE2-CD1 4.26Å; F200-F227 HydrophobicContact CE2-CD2 4.01Å; F200-F227 AromaticContact CE2-CG 3.69Å; F200-F227 HydrophobicContact CE2-CG 3.69Å; F200-F227 HydrophobicContact CG-CD1 4.12Å; F200-F227 HydrophobicContact CG-CE1 4.36Å; F200-F227 HydrophobicContact CG-CG 4.34Å; F200-F227 HydrophobicContact CZ-CB 4.24Å; I222-F227 HydrophobicContact CG2-CB 4.35Å; S223-F227 PolarHBondContact O-N 3.08Å; L225-F227 VanDerWaalsContact C-N 3.31Å; L225-F227 PolarHBondContact O-N 3.31Å; F227-L229 VanDerWaalsContact C-N 3.32Å; F227-L229 PolarHBondContact O-N 2.82Å; F227-I230 PolarHBondContact O-N 3.32Å; F227-L231 HydrophobicContact CE1-CD2 4.41Å; F227-L231 WeakPolarHBondContact O-CB 3.14Å; F227-L231 PolarHBondContact O-N 3.32Å; F227-L463 HydrophobicContact CE2-CD2 4.35Å; F227-L463 HydrophobicContact CZ-CD2 3.92Å
228K92.9Very high87.2Confident33 Ų3361.1 Ų61.114%0.14333%0.329CS..Hα-helixtrans-62.1-37.8176.7-71.2-174.4-178.4-162.20112.1L185 E197 K224 L225 L231 A232L185-K228 HydrophobicContact CB-CD 4.4Å; L185-K228 HydrophobicContact CD1-CB 4.43Å; L185-K228 VanDerWaalsContact CD1-O 3.32Å; L185-K228 WeakPolarHBondContact CD1-O 3.49Å; L185-K228 WeakPolarHBondContact O-CE 3.41Å; L185-K228 PolarHBondContact O-NZ 3.46Å; E197-K228 IonicContact OE1-NZ 3.94Å; E197-K228 PolarHBondContact OE1-NZ 2.85Å; K224-K228 WeakPolarHBondContact O-CG 3.33Å; K224-K228 PolarHBondContact O-N 2.94Å; K224-K228 VanDerWaalsContact O-N 3.08Å; L225-K228 PolarHBondContact O-N 3.33Å; K228-L231 PolarHBondContact O-N 2.99Å; K228-A232 WeakPolarHBondContact O-CB 3.46Å; K228-A232 PolarHBondContact O-N 3.32Å
229L93.8Very high88.9Confident79 Ų7958.1 Ų58.141%0.41431%0.308SS..Hα-helixtrans-65.2-47.6177.7-170.696.9000112.1L225 T226 F227 L231 A232 L233L225-L229 WeakPolarHBondContact O-CB 3.44Å; L225-L229 PolarHBondContact O-N 3.31Å; T226-L229 PolarHBondContact O-N 3.29Å; F227-L229 VanDerWaalsContact C-N 3.32Å; F227-L229 PolarHBondContact O-N 2.82Å; L229-L231 VanDerWaalsContact C-N 3.27Å; L229-L231 PolarHBondContact O-N 2.89Å; L229-A232 PolarHBondContact O-N 2.89Å; L229-L233 HydrophobicContact CD2-CD1 4.43Å; L229-L233 WeakPolarHBondContact O-CG 3.23Å; L229-L233 PolarHBondContact O-N 3.28Å
230I94.5Very high90.6Very high97 Ų9748.6 Ų48.650%0.49727%0.265SS..Hα-helixtrans-59.5-43.7177.1-69.1167.8000109.8T226 F227 L233 L234T226-I230 HydrophobicContact CG2-CD1 3.99Å; T226-I230 WeakPolarHBondContact O-CG1 3.46Å; T226-I230 PolarHBondContact O-N 3.35Å; F227-I230 PolarHBondContact O-N 3.32Å; I230-L233 PolarHBondContact O-N 2.99Å; I230-L234 PolarHBondContact O-N 3.03Å
231L94.9Very high92.2Very high8 Ų848.6 Ų48.64%0.04226%0.26CS..Hα-helixtrans-64.6-41.2178-17057.8000111.9L185 L196 F227 K228 L229 L233 L234 C235 L463 F466 F467L185-L231 HydrophobicContact CD1-CB 4.23Å; L185-L231 HydrophobicContact CD1-CD2 4.42Å; L185-L231 HydrophobicContact CD1-CG 4.31Å; L185-L231 HydrophobicContact CD2-CD2 3.6Å; L185-L231 HydrophobicContact CD2-CG 4.27Å; L196-L231 HydrophobicContact CD1-CD2 4.05Å; L196-L231 HydrophobicContact CD2-CD2 3.54Å; L196-L231 HydrophobicContact CG-CD2 4.42Å; F227-L231 HydrophobicContact CE1-CD2 4.41Å; F227-L231 WeakPolarHBondContact O-CB 3.14Å; F227-L231 PolarHBondContact O-N 3.32Å; K228-L231 PolarHBondContact O-N 2.99Å; L229-L231 VanDerWaalsContact C-N 3.27Å; L229-L231 PolarHBondContact O-N 2.89Å; L231-L233 PolarHBondContact O-N 3.26Å; L231-L234 PolarHBondContact O-N 3.43Å; L231-C235 VanDerWaalsContact O-CB 3.31Å; L231-C235 WeakPolarHBondContact O-CB 3.26Å; L231-C235 PolarHBondContact O-N 2.92Å; L231-C235 PolarHBondContact O-SG 3.41Å; L231-L463 HydrophobicContact CD1-CD2 4.49Å; L231-F466 HydrophobicContact CD1-CD1 3.94Å; L231-F466 HydrophobicContact CD1-CE1 3.72Å; L231-F466 HydrophobicContact CD2-CD1 3.84Å; L231-F466 HydrophobicContact CD2-CE1 3.67Å; L231-F466 HydrophobicContact CD2-CZ 4.31Å; L231-F466 HydrophobicContact CG-CD1 4.08Å; L231-F466 HydrophobicContact CG-CE1 3.56Å; L231-F466 HydrophobicContact CG-CZ 4.31Å; L231-F467 HydrophobicContact CD1-CE1 3.71Å; L231-F467 HydrophobicContact CD1-CE2 4.28Å; L231-F467 HydrophobicContact CD1-CZ 3.41Å; L231-F467 VanDerWaalsContact CD1-CZ 3.41Å
232A96.6Very high93.5Very high0 Ų046.1 Ų46.10%024%0.244CC..Hα-helixtrans-62.4-39.2174.800000112.8F178 A181 M182 L185 K228 L229 C235 S236F178-A232 HydrophobicContact CD2-CB 4.22Å; F178-A232 HydrophobicContact CE2-CB 3.97Å; A181-A232 HydrophobicContact CB-CB 4.16Å; M182-A232 HydrophobicContact CG-CB 4.05Å; M182-A232 HydrophobicContact SD-CB 3.68Å; L185-A232 HydrophobicContact CD1-CB 3.99Å; K228-A232 WeakPolarHBondContact O-CB 3.46Å; K228-A232 PolarHBondContact O-N 3.32Å; L229-A232 PolarHBondContact O-N 2.89Å; A232-C235 WeakPolarHBondContact O-CB 3.07Å; A232-C235 PolarHBondContact O-N 2.95Å; A232-S236 WeakPolarHBondContact O-CB 3.41Å; A232-S236 PolarHBondContact O-N 3.29Å
233L96.8Very high94Very high94 Ų9443 Ų4349%0.49223%0.228SC..Hα-helixtrans-65.5-43.8175.4-71.2170.7000111.7F178 L229 I230 L231 C235 S236 L237F178-L233 HydrophobicContact CD2-CD2 4.15Å; F178-L233 HydrophobicContact CE2-CD2 3.81Å; F178-L233 HydrophobicContact CE2-CG 4.2Å; L229-L233 HydrophobicContact CD2-CD1 4.43Å; L229-L233 WeakPolarHBondContact O-CG 3.23Å; L229-L233 PolarHBondContact O-N 3.28Å; I230-L233 PolarHBondContact O-N 2.99Å; L231-L233 PolarHBondContact O-N 3.26Å; L233-C235 VanDerWaalsContact C-N 3.32Å; L233-C235 PolarHBondContact O-N 3.26Å; L233-S236 WeakPolarHBondContact O-CB 3.45Å; L233-S236 PolarHBondContact O-N 3.36Å; L233-L237 PolarHBondContact O-N 3.36Å
234L96.3Very high94.3Very high73 Ų7340.9 Ų40.938%0.38221%0.211SC..Hα-helixtrans-63.6-40.6175.3-178.658.2000111.5I230 L231 S236 L237 I238 F467I230-L234 PolarHBondContact O-N 3.03Å; L231-L234 PolarHBondContact O-N 3.43Å; L234-S236 PolarHBondContact O-N 2.93Å; L234-L237 PolarHBondContact O-N 3.26Å; L234-I238 HydrophobicContact CD1-CD1 4.25Å; L234-I238 HydrophobicContact CD1-CG1 4.43Å; L234-I238 HydrophobicContact CG-CD1 4.03Å; L234-I238 WeakPolarHBondContact O-CG1 3.09Å; L234-I238 PolarHBondContact O-N 2.87Å; L234-F467 HydrophobicContact CD2-CE1 3.57Å; L234-F467 HydrophobicContact CD2-CE2 4.49Å; L234-F467 HydrophobicContact CD2-CZ 3.38Å; L234-F467 HydrophobicContact CG-CE1 4.02Å; L234-F467 HydrophobicContact CG-CZ 4.32Å
235C96.8Very high94.6Very high0 Ų037 Ų370%020%0.195CC..Hα-helixtrans-61.1-42.1174.2-81.20000113.2A181 L231 A232 L233 G239 F466 W470A181-C235 HydrophobicContact CB-CB 3.58Å; L231-C235 VanDerWaalsContact O-CB 3.31Å; L231-C235 WeakPolarHBondContact O-CB 3.26Å; L231-C235 PolarHBondContact O-N 2.92Å; L231-C235 PolarHBondContact O-SG 3.41Å; A232-C235 WeakPolarHBondContact O-CB 3.07Å; A232-C235 PolarHBondContact O-N 2.95Å; L233-C235 VanDerWaalsContact C-N 3.32Å; L233-C235 PolarHBondContact O-N 3.26Å; C235-G239 PolarHBondContact O-N 2.96Å; C235-F466 WeakPolarHBondContact SG-CE1 3.37Å; C235-F466 VanDerWaalsContact SG-CZ 3.56Å; C235-W470 VanDerWaalsContact CA-NE1 3.3Å; C235-W470 HydrophobicContact CB-CD2 4Å; C235-W470 HydrophobicContact CB-CG 4.42Å; C235-W470 HydrophobicContact CB-CH2 4.33Å; C235-W470 HydrophobicContact CB-CZ2 3.58Å; C235-W470 PolarHBondContact O-NE1 3.34Å
236S97.4Very high94.8Very high18 Ų1831 Ų3113%0.12616%0.164CC..Hα-helixtrans-59.9-45.6173.71770000111.4A174 A232 L233 L234 G239 A240A174-S236 PolarHBondContact O-OG 3.41Å; A232-S236 WeakPolarHBondContact O-CB 3.41Å; A232-S236 PolarHBondContact O-N 3.29Å; L233-S236 WeakPolarHBondContact O-CB 3.45Å; L233-S236 PolarHBondContact O-N 3.36Å; L234-S236 PolarHBondContact O-N 2.93Å; S236-G239 PolarHBondContact O-N 3.45Å; S236-A240 WeakPolarHBondContact O-CB 3.21Å; S236-A240 PolarHBondContact O-N 2.86Å
237L96.3Very high94.9Very high85 Ų8529.2 Ų29.245%0.44515%0.151SC..Hα-helixtrans-63.4-47.6178.5-174.265.7000112.1L233 L234 G239 A240 F241L233-L237 PolarHBondContact O-N 3.36Å; L234-L237 PolarHBondContact O-N 3.26Å; L237-G239 VanDerWaalsContact C-N 3.3Å; L237-G239 PolarHBondContact O-N 2.82Å; L237-A240 WeakPolarHBondContact O-CB 3.29Å; L237-A240 PolarHBondContact O-N 2.94Å; L237-F241 HydrophobicContact CD1-CE1 3.86Å; L237-F241 HydrophobicContact CD1-CE2 3.93Å; L237-F241 HydrophobicContact CD1-CZ 3.47Å; L237-F241 VanDerWaalsContact CD1-CZ 3.47Å; L237-F241 HydrophobicContact CD2-CE2 4.09Å; L237-F241 HydrophobicContact CD2-CZ 4.27Å; L237-F241 HydrophobicContact CG-CD2 4.27Å; L237-F241 HydrophobicContact CG-CE1 4.47Å; L237-F241 HydrophobicContact CG-CE2 3.68Å; L237-F241 HydrophobicContact CG-CZ 3.8Å; L237-F241 WeakPolarHBondContact O-CG 3.27Å; L237-F241 PolarHBondContact O-N 2.98Å
238I96.6Very high94.9Very high20 Ų2029.8 Ų29.810%0.10315%0.153CC..Hα-helixtrans-59.7-44.1175.4-67.2167.4000110.1L234 A240 F241 L242 M383 F467 I471L234-I238 HydrophobicContact CD1-CD1 4.25Å; L234-I238 HydrophobicContact CD1-CG1 4.43Å; L234-I238 HydrophobicContact CG-CD1 4.03Å; L234-I238 WeakPolarHBondContact O-CG1 3.09Å; L234-I238 PolarHBondContact O-N 2.87Å; I238-A240 PolarHBondContact O-N 2.87Å; I238-F241 PolarHBondContact O-N 3.33Å; I238-L242 HydrophobicContact CG2-CD1 3.84Å; I238-L242 HydrophobicContact CG2-CG 4.35Å; I238-L242 WeakPolarHBondContact O-CB 3.27Å; I238-L242 VanDerWaalsContact O-CG 3.27Å; I238-L242 WeakPolarHBondContact O-CG 3.33Å; I238-L242 PolarHBondContact O-N 3.13Å; I238-M383 HydrophobicContact CG2-CE 4.25Å; I238-F467 HydrophobicContact CD1-CD1 4.03Å; I238-F467 HydrophobicContact CD1-CE1 4.12Å; I238-I471 HydrophobicContact CG2-CG1 4.25Å
239G96.3Very high94.8Very high0 Ų028.4 Ų28.40%015%0.147CC..Hα-helixtrans-61.3-42.2177.300000113F177 C235 S236 L237 L242 T243F177-G239 VanDerWaalsContact CD2-C 3.43Å; F177-G239 WeakPolarHBondContact CE2-O 3.27Å; C235-G239 PolarHBondContact O-N 2.96Å; S236-G239 PolarHBondContact O-N 3.45Å; L237-G239 VanDerWaalsContact C-N 3.3Å; L237-G239 PolarHBondContact O-N 2.82Å; G239-L242 PolarHBondContact O-N 3.39Å; G239-T243 PolarHBondContact O-N 3.35Å; G239-T243 VanDerWaalsContact O-N 3.11Å; G239-T243 PolarHBondContact O-OG1 3.05Å
240A95.3Very high94.8Very high8 Ų824.6 Ų24.67%0.06613%0.127CC..Hα-helixtrans-61.1-47.8175.400000111.4A174 S236 L237 I238 L242 T243A174-A240 HydrophobicContact CB-CB 3.79Å; S236-A240 WeakPolarHBondContact O-CB 3.21Å; S236-A240 PolarHBondContact O-N 2.86Å; L237-A240 WeakPolarHBondContact O-CB 3.29Å; L237-A240 PolarHBondContact O-N 2.94Å; I238-A240 PolarHBondContact O-N 2.87Å; A240-L242 VanDerWaalsContact C-N 3.27Å; A240-L242 PolarHBondContact O-N 2.94Å; A240-T243 VanDerWaalsContact O-CB 3.24Å; A240-T243 WeakPolarHBondContact O-CB 3.42Å; A240-T243 PolarHBondContact O-N 3.13Å; A240-T243 VanDerWaalsContact O-N 3.15Å; A240-T243 PolarHBondContact O-OG1 3.49Å
241F95.1Very high94.6Very high17 Ų1721.8 Ų21.88%0.07511%0.112CC..Hα-helixtrans-62-32.6176.9-70.7-14.3000113.6I148 L151 F152 T155 L237 I238 P245I148-F241 HydrophobicContact CG2-CE2 4.26Å; L151-F241 HydrophobicContact CB-CB 4.02Å; L151-F241 HydrophobicContact CB-CD2 4.32Å; L151-F241 HydrophobicContact CB-CG 4.2Å; L151-F241 HydrophobicContact CD1-CB 4.29Å; F152-F241 HydrophobicContact CB-CE1 4.35Å; F152-F241 HydrophobicContact CB-CE2 4.45Å; F152-F241 HydrophobicContact CB-CZ 3.98Å; F152-F241 HydrophobicContact CD2-CE1 4.06Å; F152-F241 AromaticContact CD2-CZ 3.82Å; F152-F241 HydrophobicContact CD2-CZ 3.82Å; F152-F241 HydrophobicContact CG-CZ 4.41Å; T155-F241 HydrophobicContact CG2-CD1 4.29Å; T155-F241 HydrophobicContact CG2-CE1 4.45Å; T155-F241 WeakPolarHBondContact OG1-CD1 3.47Å; L237-F241 HydrophobicContact CD1-CE1 3.86Å; L237-F241 HydrophobicContact CD1-CE2 3.93Å; L237-F241 HydrophobicContact CD1-CZ 3.47Å; L237-F241 VanDerWaalsContact CD1-CZ 3.47Å; L237-F241 HydrophobicContact CD2-CE2 4.09Å; L237-F241 HydrophobicContact CD2-CZ 4.27Å; L237-F241 HydrophobicContact CG-CD2 4.27Å; L237-F241 HydrophobicContact CG-CE1 4.47Å; L237-F241 HydrophobicContact CG-CE2 3.68Å; L237-F241 HydrophobicContact CG-CZ 3.8Å; L237-F241 WeakPolarHBondContact O-CG 3.27Å; L237-F241 PolarHBondContact O-N 2.98Å; I238-F241 PolarHBondContact O-N 3.33Å; F241-P245 VanDerWaalsContact O-CD 3.27Å; F241-P245 WeakPolarHBondContact O-CD 3.45Å; F241-P245 WeakPolarHBondContact O-CG 3.34Å
242L95.8Very high94.5Very high0 Ų021.5 Ų21.50%011%0.11CC..Hα-helixtrans-85.7-4178.3-66.8-179.4000114.3L151 I238 G239 A240 G246 P380 M383 I471 C474 L475L151-L242 HydrophobicContact CD1-CD2 4.32Å; I238-L242 HydrophobicContact CG2-CD1 3.84Å; I238-L242 HydrophobicContact CG2-CG 4.35Å; I238-L242 WeakPolarHBondContact O-CB 3.27Å; I238-L242 VanDerWaalsContact O-CG 3.27Å; I238-L242 WeakPolarHBondContact O-CG 3.33Å; I238-L242 PolarHBondContact O-N 3.13Å; G239-L242 PolarHBondContact O-N 3.39Å; A240-L242 VanDerWaalsContact C-N 3.27Å; A240-L242 PolarHBondContact O-N 2.94Å; L242-G246 PolarHBondContact O-N 3.46Å; L242-P380 HydrophobicContact CD2-CB 3.63Å; L242-P380 HydrophobicContact CD2-CG 3.6Å; L242-M383 HydrophobicContact CD1-CE 3.81Å; L242-M383 HydrophobicContact CD2-CE 3.8Å; L242-M383 HydrophobicContact CG-CE 4.11Å; L242-I471 HydrophobicContact CD1-CG2 4.2Å; L242-C474 HydrophobicContact CB-CB 4.38Å; L242-C474 HydrophobicContact CD1-CB 3.74Å; L242-L475 HydrophobicContact CD1-CG 4.39Å; L242-L475 HydrophobicContact CD2-CD2 4.39Å
243T93.9Very high94.4Very high0 Ų021.7 Ų21.70%011%0.111CC..Hα-helixtrans-61-59.9-177.9-63.30000112.2F173 G239 A240 G246 L247F173-T243 HydrophobicContact CB-CG2 3.7Å; F173-T243 WeakPolarHBondContact CB-OG1 3.4Å; F173-T243 HydrophobicContact CD1-CG2 4.14Å; F173-T243 HydrophobicContact CD2-CG2 3.29Å; F173-T243 HydrophobicContact CE2-CG2 3.87Å; F173-T243 HydrophobicContact CG-CG2 3.44Å; F173-T243 VanDerWaalsContact CG-CG2 3.44Å; G239-T243 PolarHBondContact O-N 3.35Å; G239-T243 VanDerWaalsContact O-N 3.11Å; G239-T243 PolarHBondContact O-OG1 3.05Å; A240-T243 VanDerWaalsContact O-CB 3.24Å; A240-T243 WeakPolarHBondContact O-CB 3.42Å; A240-T243 PolarHBondContact O-N 3.13Å; A240-T243 VanDerWaalsContact O-N 3.15Å; A240-T243 PolarHBondContact O-OG1 3.49Å; T243-G246 PolarHBondContact O-N 3.04Å; T243-L247 HydrophobicContact CG2-CD1 3.98Å; T243-L247 WeakPolarHBondContact O-CG 3.49Å; T243-L247 PolarHBondContact O-N 3.33Å
244F92.1Very high94.1Very high17 Ų1718.8 Ų18.88%0.07510%0.096CC..Hα-helixtrans-63.5-44.9179.3-62.9-70.8000113.1Y158 E166 C170 G246 L247 R248Y158-F244 HydrophobicContact CD1-CE1 4.44Å; Y158-F244 HydrophobicContact CD1-CZ 4.43Å; Y158-F244 AromaticContact CD2-CD2 3.66Å; Y158-F244 HydrophobicContact CD2-CD2 3.66Å; Y158-F244 AromaticContact CD2-CE2 3.88Å; Y158-F244 HydrophobicContact CD2-CE2 3.88Å; Y158-F244 HydrophobicContact CD2-CG 4.04Å; Y158-F244 HydrophobicContact CD2-CZ 4.44Å; Y158-F244 HydrophobicContact CE2-CB 4.11Å; Y158-F244 HydrophobicContact CE2-CD2 4.07Å; Y158-F244 HydrophobicContact CE2-CG 4.03Å; Y158-F244 HydrophobicContact CG-CD2 4.1Å; Y158-F244 HydrophobicContact CG-CE1 4.44Å; Y158-F244 AromaticContact CG-CE2 3.88Å; Y158-F244 HydrophobicContact CG-CE2 3.88Å; Y158-F244 HydrophobicContact CG-CG 4.46Å; Y158-F244 HydrophobicContact CG-CZ 4.06Å; E166-F244 HydrophobicContact CB-CE1 4.14Å; E166-F244 HydrophobicContact CB-CZ 4Å; E166-F244 HydrophobicContact CG-CE1 4.44Å; E166-F244 WeakPolarHBondContact O-CZ 3.42Å; C170-F244 HydrophobicContact CB-CE2 3.86Å; C170-F244 HydrophobicContact CB-CZ 4.06Å; F244-G246 VanDerWaalsContact C-N 3.3Å; F244-G246 PolarHBondContact O-N 2.85Å; F244-L247 PolarHBondContact O-N 3.04Å; F244-R248 VanDerWaalsContact O-CB 3.23Å; F244-R248 WeakPolarHBondContact O-CB 3.39Å; F244-R248 PolarHBondContact O-N 2.9Å
245P93.9Very high93.8Very high8 Ų816.3 Ų16.35%0.0528%0.083CC..Hα-helixtrans-49.1-46.4171.1-33.237.8000114.6L151 F241 L249 Q376 P380L151-P245 HydrophobicContact CD2-CG 4.19Å; F241-P245 VanDerWaalsContact O-CD 3.27Å; F241-P245 WeakPolarHBondContact O-CD 3.45Å; F241-P245 WeakPolarHBondContact O-CG 3.34Å; P245-L249 WeakPolarHBondContact O-CB 3.35Å; P245-L249 PolarHBondContact O-N 3.02Å; P245-Q376 HydrophobicContact CB-CB 4.36Å; P245-Q376 WeakPolarHBondContact CB-O 3.47Å; P245-Q376 HydrophobicContact CG-CB 4.3Å; P245-Q376 HydrophobicContact CG-CG 4.25Å; P245-P380 HydrophobicContact CB-CG 3.87Å; P245-P380 HydrophobicContact CG-CG 4.4Å
246G93.2Very high93.6Very high0 Ų016.3 Ų16.30%08%0.083CC..Hα-helixtrans-71.7-44.4-179.100000113.9L242 T243 F244 R248 L249 A250 T478 S479L242-G246 PolarHBondContact O-N 3.46Å; T243-G246 PolarHBondContact O-N 3.04Å; F244-G246 VanDerWaalsContact C-N 3.3Å; F244-G246 PolarHBondContact O-N 2.85Å; G246-R248 VanDerWaalsContact C-N 3.26Å; G246-R248 PolarHBondContact O-N 3.45Å; G246-L249 WeakPolarHBondContact O-CB 3.47Å; G246-L249 PolarHBondContact O-N 3.37Å; G246-A250 PolarHBondContact O-N 3.06Å; G246-A250 VanDerWaalsContact O-N 3.11Å; G246-T478 WeakPolarHBondContact CA-OG1 3.37Å; G246-S479 WeakPolarHBondContact O-CA 3.34Å
247L92.4Very high93.3Very high24 Ų2416.5 Ų16.513%0.1268%0.082CC..Hα-helixtrans-58.4-42.6175.6-68.2174.2000111.3L169 F173 T243 F244 A250 Q251 F481L169-L247 HydrophobicContact CD2-CD1 3.63Å; L169-L247 HydrophobicContact CG-CD1 4.48Å; F173-L247 HydrophobicContact CE2-CD1 4.4Å; F173-L247 HydrophobicContact CZ-CD2 4.42Å; T243-L247 HydrophobicContact CG2-CD1 3.98Å; T243-L247 WeakPolarHBondContact O-CG 3.49Å; T243-L247 PolarHBondContact O-N 3.33Å; F244-L247 PolarHBondContact O-N 3.04Å; L247-A250 PolarHBondContact O-N 3.42Å; L247-Q251 PolarHBondContact O-N 3.29Å; L247-F481 HydrophobicContact CD2-CB 4.34Å
248R91Very high92.9Very high44 Ų4418.8 Ų18.817%0.16610%0.095CC..Hα-helixtrans-69.6-39.3179.4-167.173.8-134.5175.38.8112.1F244 G246 A250 Q251 M252 I373F244-R248 VanDerWaalsContact O-CB 3.23Å; F244-R248 WeakPolarHBondContact O-CB 3.39Å; F244-R248 PolarHBondContact O-N 2.9Å; G246-R248 VanDerWaalsContact C-N 3.26Å; G246-R248 PolarHBondContact O-N 3.45Å; R248-A250 VanDerWaalsContact C-N 3.28Å; R248-A250 PolarHBondContact O-N 3.22Å; R248-Q251 VanDerWaalsContact CZ-CD 3.43Å; R248-Q251 VanDerWaalsContact NH2-NE2 3.18Å; R248-Q251 PolarHBondContact O-N 2.94Å; R248-M252 HydrophobicContact CB-CE 4.25Å; R248-M252 HydrophobicContact CG-CE 3.57Å; R248-M252 WeakPolarHBondContact O-CG 3.5Å; R248-M252 PolarHBondContact O-N 3.04Å; R248-I373 HydrophobicContact CG-CD1 3.95Å
249L92.8Very high92.4Very high4 Ų421.5 Ų21.52%0.02111%0.11CC..Hα-helixtrans-57.1-43.6174.6-179.471.6000111.3P245 G246 Q251 M252 H253 Y377P245-L249 WeakPolarHBondContact O-CB 3.35Å; P245-L249 PolarHBondContact O-N 3.02Å; G246-L249 WeakPolarHBondContact O-CB 3.47Å; G246-L249 PolarHBondContact O-N 3.37Å; L249-Q251 VanDerWaalsContact C-N 3.34Å; L249-Q251 PolarHBondContact O-N 2.94Å; L249-M252 PolarHBondContact O-N 2.63Å; L249-H253 VanDerWaalsContact O-CB 3.3Å; L249-H253 WeakPolarHBondContact O-CB 3.06Å; L249-H253 PolarHBondContact O-N 3.02Å; L249-Y377 HydrophobicContact CD1-CD2 3.72Å; L249-Y377 HydrophobicContact CD1-CE2 3.4Å
250A92.8Very high91.9Very high0 Ų022.6 Ų22.60%012%0.116CC..Hα-helixtrans-60.2-44.417900000112.2G246 L247 R248 H253 L254 F273 S479 G482 L483G246-A250 PolarHBondContact O-N 3.06Å; G246-A250 VanDerWaalsContact O-N 3.11Å; L247-A250 PolarHBondContact O-N 3.42Å; R248-A250 VanDerWaalsContact C-N 3.28Å; R248-A250 PolarHBondContact O-N 3.22Å; A250-H253 PolarHBondContact O-N 3.25Å; A250-L254 PolarHBondContact O-N 3.48Å; A250-L254 VanDerWaalsContact O-N 3.1Å; A250-F273 HydrophobicContact CB-CE2 4.48Å; A250-S479 VanDerWaalsContact CB-O 3.24Å; A250-S479 WeakPolarHBondContact CB-O 3.42Å; A250-G482 VanDerWaalsContact CB-C 3.47Å; A250-L483 HydrophobicContact CB-CD2 4.22Å; A250-L483 HydrophobicContact CB-CG 4.15Å
251Q91.3Very high91.4Very high37 Ų3728.8 Ų28.817%0.17315%0.153CC..Hα-helixtrans-61.3-50.6175.5-171.11761.500111.5L247 R248 L249 H253 L254 D255 H486L247-Q251 PolarHBondContact O-N 3.29Å; R248-Q251 VanDerWaalsContact CZ-CD 3.43Å; R248-Q251 VanDerWaalsContact NH2-NE2 3.18Å; R248-Q251 PolarHBondContact O-N 2.94Å; L249-Q251 VanDerWaalsContact C-N 3.34Å; L249-Q251 PolarHBondContact O-N 2.94Å; Q251-H253 PolarHBondContact O-N 3.28Å; Q251-L254 PolarHBondContact O-N 3.31Å; Q251-D255 WeakPolarHBondContact O-CB 3.47Å; Q251-D255 VanDerWaalsContact O-CG 3.31Å; Q251-D255 PolarHBondContact O-N 3.34Å; Q251-H486 PolarHBondContact OE1-NE2 2.88Å
252M92.5Very high91.2Very high2 Ų230.2 Ų30.21%0.0117%0.168CC..Hα-helixtrans-60.8-34.3179.3-70.5-170.6-91.600112.2R248 L249 A256 H332 I373 Y377R248-M252 HydrophobicContact CB-CE 4.25Å; R248-M252 HydrophobicContact CG-CE 3.57Å; R248-M252 WeakPolarHBondContact O-CG 3.5Å; R248-M252 PolarHBondContact O-N 3.04Å; L249-M252 PolarHBondContact O-N 2.63Å; M252-A256 WeakPolarHBondContact O-CB 3.24Å; M252-A256 PolarHBondContact O-N 3.44Å; M252-H332 HydrophobicContact CB-CB 4.18Å; M252-H332 HydrophobicContact SD-CB 4.35Å; M252-I373 HydrophobicContact CE-CG2 3.49Å; M252-I373 VanDerWaalsContact CE-CG2 3.49Å; M252-I373 HydrophobicContact SD-CG2 3.4Å; M252-I373 WeakPolarHBondContact SD-CG2 3.42Å; M252-Y377 HydrophobicContact CE-CD2 4.44Å
253H93.1Very high91Very high5 Ų538.3 Ų38.32%0.02320%0.203CC..Hα-helixtrans-67.2-49.5178177.863.9000111.9L249 A250 Q251 D255 A256 L257 L269 F273L249-H253 VanDerWaalsContact O-CB 3.3Å; L249-H253 WeakPolarHBondContact O-CB 3.06Å; L249-H253 PolarHBondContact O-N 3.02Å; A250-H253 PolarHBondContact O-N 3.25Å; Q251-H253 PolarHBondContact O-N 3.28Å; H253-D255 VanDerWaalsContact C-N 3.29Å; H253-D255 PolarHBondContact O-N 2.93Å; H253-A256 PolarHBondContact O-N 3.33Å; H253-L257 WeakPolarHBondContact NE2-CD1 3.38Å; H253-L257 WeakPolarHBondContact O-CG 3.39Å; H253-L257 PolarHBondContact O-N 2.79Å; H253-L269 PolarHBondContact CE1-O 3.3Å; H253-F273 HydrophobicContact CB-CD2 3.96Å; H253-F273 AromaticContact CD2-CD2 3.46Å; H253-F273 VanDerWaalsContact CD2-CD2 3.46Å; H253-F273 WeakPolarHBondContact CD2-CD2 3.26Å; H253-F273 AromaticContact CD2-CG 3.64Å; H253-F273 AromaticContact CG-CD2 3.61Å; H253-F273 AromaticContact NE2-CG 3.71Å
254L91.6Very high90.9Very high33 Ų3345.5 Ų45.517%0.17324%0.235CC..Hα-helixtrans-59.6-43175.7-70.9174.8000111.6A250 Q251 L257 N258 L483 H486 Q487A250-L254 PolarHBondContact O-N 3.48Å; A250-L254 VanDerWaalsContact O-N 3.1Å; Q251-L254 PolarHBondContact O-N 3.31Å; L254-L257 PolarHBondContact O-N 3.37Å; L254-N258 PolarHBondContact O-N 2.9Å; L254-N258 PolarHBondContact O-ND2 3.48Å; L254-L483 HydrophobicContact CD1-CD2 3.66Å; L254-L483 HydrophobicContact CD2-CD2 3.68Å; L254-L483 HydrophobicContact CG-CD2 3.5Å; L254-L483 VanDerWaalsContact CG-CD2 3.5Å; L254-H486 HydrophobicContact CD1-CB 4.02Å; L254-Q487 HydrophobicContact CD1-CG 3.95Å
255D90.6Very high90.8Very high20 Ų2046 Ų4611%0.10724%0.24CC..Hα-helixtrans-64.5-41.3178-72.3-30000111.9Q251 H253 N258 L259 A335 K342Q251-D255 WeakPolarHBondContact O-CB 3.47Å; Q251-D255 VanDerWaalsContact O-CG 3.31Å; Q251-D255 PolarHBondContact O-N 3.34Å; H253-D255 VanDerWaalsContact C-N 3.29Å; H253-D255 PolarHBondContact O-N 2.93Å; D255-N258 PolarHBondContact O-N 2.87Å; D255-L259 WeakPolarHBondContact O-CD1 3.35Å; D255-L259 VanDerWaalsContact O-CG 3.26Å; D255-L259 WeakPolarHBondContact O-CG 3.46Å; D255-L259 PolarHBondContact O-N 3.3Å; D255-A335 HydrophobicContact CB-CB 3.88Å; D255-K342 IonicContact OD1-NZ 2.7Å; D255-K342 PolarHBondContact OD1-NZ 3Å; D255-K342 IonicContact OD2-NZ 2.88Å
256A91.3Very high90.7Very high1 Ų148.4 Ų48.41%0.00825%0.25CS..Hα-helixtrans-66.9-37.6178.300000112.6M252 H253 L259 T260 L269 A335M252-A256 WeakPolarHBondContact O-CB 3.24Å; M252-A256 PolarHBondContact O-N 3.44Å; H253-A256 PolarHBondContact O-N 3.33Å; A256-L259 PolarHBondContact O-N 2.9Å; A256-T260 WeakPolarHBondContact O-CB 3.31Å; A256-T260 PolarHBondContact O-N 3.29Å; A256-T260 VanDerWaalsContact O-N 3.12Å; A256-T260 PolarHBondContact O-OG1 3.18Å; A256-L269 HydrophobicContact CB-CD1 4.11Å; A256-L269 HydrophobicContact CB-CD2 4.43Å; A256-A335 HydrophobicContact CB-CB 3.78Å
257L91.9Very high90.7Very high21 Ų2151.8 Ų51.811%0.1127%0.271CS..Hα-helixtrans-62.6-42.8175.8-75.3175.9000111.7H253 L254 L259 T260 Q266 L269 Y270H253-L257 WeakPolarHBondContact NE2-CD1 3.38Å; H253-L257 WeakPolarHBondContact O-CG 3.39Å; H253-L257 PolarHBondContact O-N 2.79Å; L254-L257 PolarHBondContact O-N 3.37Å; L257-L259 VanDerWaalsContact C-N 3.28Å; L257-L259 PolarHBondContact O-N 3.11Å; L257-T260 PolarHBondContact O-N 3Å; L257-Q266 HydrophobicContact CD2-CB 4.49Å; L257-L269 HydrophobicContact CD2-CB 3.97Å; L257-L269 HydrophobicContact CD2-CD1 4.11Å; L257-Y270 HydrophobicContact CD1-CD1 4.34Å; L257-Y270 HydrophobicContact CD1-CE1 3.59Å; L257-Y270 HydrophobicContact CD2-CD2 4.44Å; L257-Y270 HydrophobicContact CD2-CE1 4.14Å; L257-Y270 HydrophobicContact CD2-CE2 4Å
258N88Confident90.8Very high133 Ų13352.3 Ų52.371%0.71127%0.274SS*.Hα-helixtrans-67.6-27.7179.4-72.2-26.9000113.3L254 D255L254-N258 PolarHBondContact O-N 2.9Å; L254-N258 PolarHBondContact O-ND2 3.48Å; D255-N258 PolarHBondContact O-N 2.87Å
259L85.5Confident91Very high78 Ų7850.2 Ų50.241%0.40827%0.266SS..Hα-helixtrans-87.2-21.9-179.2-68.4166.1000113.2D255 A256 L257 A335 N338D255-L259 WeakPolarHBondContact O-CD1 3.35Å; D255-L259 VanDerWaalsContact O-CG 3.26Å; D255-L259 WeakPolarHBondContact O-CG 3.46Å; D255-L259 PolarHBondContact O-N 3.3Å; A256-L259 PolarHBondContact O-N 2.9Å; L257-L259 VanDerWaalsContact C-N 3.28Å; L257-L259 PolarHBondContact O-N 3.11Å; L259-A335 HydrophobicContact CD1-CB 3.85Å; L259-N338 HydrophobicContact CD1-CB 4Å; L259-N338 WeakPolarHBondContact CD1-ND2 3.41Å
260T86.6Confident91.1Very high23 Ų2356.2 Ų56.214%0.14129%0.289CS..  trans-93.1124.1-173.5-57.80000110.5A256 L257 T265 Q266A256-T260 WeakPolarHBondContact O-CB 3.31Å; A256-T260 PolarHBondContact O-N 3.29Å; A256-T260 VanDerWaalsContact O-N 3.12Å; A256-T260 PolarHBondContact O-OG1 3.18Å; L257-T260 PolarHBondContact O-N 3Å; T260-T265 HydrophobicContact CG2-CG2 3.7Å; T260-Q266 HydrophobicContact CG2-CG 4.05Å; T260-Q266 PolarHBondContact O-NE2 3.45Å
261T84.3Confident91.1Very high137 Ų13760 Ų6084%0.8431%0.308SS*.  trans-95-24.7177.354.30000113.5K263T261-K263 PolarHBondContact O-N 2.91Å
262A91.1Very high91.3Very high47 Ų4758.2 Ų58.239%0.38830%0.3SS..  trans-75.8121.4-177.600000111.8F264 T265 Q266A262-F264 VanDerWaalsContact C-N 3.29Å; A262-F264 PolarHBondContact O-N 3.44Å; A262-T265 PolarHBondContact O-N 2.88Å; A262-Q266 WeakPolarHBondContact O-CG 3.2Å; A262-Q266 PolarHBondContact O-N 2.79Å
263K90.3Very high91.3Very high170 Ų17059.2 Ų59.274%0.73931%0.305SS*.Hα-helixtrans-57.5-38.8-179.7-65.1-175.1-179.2179.90113T261 Q266 T267T261-K263 PolarHBondContact O-N 2.91Å; K263-Q266 WeakPolarHBondContact O-CB 3.48Å; K263-Q266 PolarHBondContact O-N 3.46Å; K263-T267 WeakPolarHBondContact O-CG2 3.1Å; K263-T267 PolarHBondContact O-N 3.44Å; K263-T267 PolarHBondContact O-OG1 2.84Å
264F91.9Very high91.4Very high151 Ų15162.7 Ų62.766%0.66232%0.323SS*.Hα-helixtrans-60.1-53.5177.8-177.7-105.1000111.2A262 Q266 T267 L268A262-F264 VanDerWaalsContact C-N 3.29Å; A262-F264 PolarHBondContact O-N 3.44Å; F264-Q266 VanDerWaalsContact C-N 3.29Å; F264-Q266 PolarHBondContact O-N 3.29Å; F264-T267 PolarHBondContact O-N 3.49Å; F264-T267 PolarHBondContact O-OG1 2.99Å; F264-L268 HydrophobicContact CD1-CD1 3.65Å; F264-L268 HydrophobicContact CD2-CD1 3.88Å; F264-L268 HydrophobicContact CE1-CD1 3.43Å; F264-L268 VanDerWaalsContact CE1-CD1 3.43Å; F264-L268 HydrophobicContact CE1-CD2 4.28Å; F264-L268 HydrophobicContact CE2-CD1 3.67Å; F264-L268 HydrophobicContact CG-CD1 3.89Å; F264-L268 HydrophobicContact CZ-CD1 3.45Å; F264-L268 VanDerWaalsContact CZ-CD1 3.45Å; F264-L268 HydrophobicContact CZ-CD2 4.46Å; F264-L268 WeakPolarHBondContact O-CD1 3.32Å; F264-L268 PolarHBondContact O-N 3.17Å
265T90.6Very high91.5Very high29 Ų2961.2 Ų61.218%0.17832%0.315CS..Hα-helixtrans-60.8-38177.9-51.50000112T260 A262 T267 L268 L269T260-T265 HydrophobicContact CG2-CG2 3.7Å; A262-T265 PolarHBondContact O-N 2.88Å; T265-T267 PolarHBondContact O-N 3.09Å; T265-L268 PolarHBondContact O-N 2.84Å; T265-L269 HydrophobicContact CG2-CD1 4.46Å; T265-L269 VanDerWaalsContact O-CG 3.31Å; T265-L269 WeakPolarHBondContact O-CG 3.4Å; T265-L269 PolarHBondContact O-N 3.38Å
266Q92.7Very high91.6Very high58 Ų5860.4 Ų60.427%0.27131%0.311SS..Hα-helixtrans-59.4-45.7172.5-70.6177.1-15.100112L257 T260 A262 K263 F264 L268 L269 Y270L257-Q266 HydrophobicContact CD2-CB 4.49Å; T260-Q266 HydrophobicContact CG2-CG 4.05Å; T260-Q266 PolarHBondContact O-NE2 3.45Å; A262-Q266 WeakPolarHBondContact O-CG 3.2Å; A262-Q266 PolarHBondContact O-N 2.79Å; K263-Q266 WeakPolarHBondContact O-CB 3.48Å; K263-Q266 PolarHBondContact O-N 3.46Å; F264-Q266 VanDerWaalsContact C-N 3.29Å; F264-Q266 PolarHBondContact O-N 3.29Å; Q266-L268 VanDerWaalsContact C-N 3.35Å; Q266-L268 PolarHBondContact O-N 3.29Å; Q266-L269 WeakPolarHBondContact O-CB 3.23Å; Q266-L269 PolarHBondContact O-N 3.18Å; Q266-Y270 HydrophobicContact CB-CE2 4.48Å; Q266-Y270 WeakPolarHBondContact O-CD2 3.36Å; Q266-Y270 PolarHBondContact O-N 3.06Å
267T93.6Very high91.7Very high71 Ų7162.4 Ų62.444%0.43632%0.321SS..Hα-helixtrans-61-41.8176.258.20000112.2K263 F264 T265 L269 Y270 I271K263-T267 WeakPolarHBondContact O-CG2 3.1Å; K263-T267 PolarHBondContact O-N 3.44Å; K263-T267 PolarHBondContact O-OG1 2.84Å; F264-T267 PolarHBondContact O-N 3.49Å; F264-T267 PolarHBondContact O-OG1 2.99Å; T265-T267 PolarHBondContact O-N 3.09Å; T267-L269 VanDerWaalsContact C-N 3.33Å; T267-L269 PolarHBondContact O-N 3.41Å; T267-Y270 PolarHBondContact O-N 3.48Å; T267-I271 VanDerWaalsContact O-CG1 3.3Å; T267-I271 WeakPolarHBondContact O-CG1 3.38Å; T267-I271 PolarHBondContact O-N 3.5Å
268L94.4Very high91.8Very high34 Ų3464 Ų6418%0.17833%0.329CS..Hα-helixtrans-64.5-37175.3-82.685.6000112.2F264 T265 Q266 I271 N272 L324 M328F264-L268 HydrophobicContact CD1-CD1 3.65Å; F264-L268 HydrophobicContact CD2-CD1 3.88Å; F264-L268 HydrophobicContact CE1-CD1 3.43Å; F264-L268 VanDerWaalsContact CE1-CD1 3.43Å; F264-L268 HydrophobicContact CE1-CD2 4.28Å; F264-L268 HydrophobicContact CE2-CD1 3.67Å; F264-L268 HydrophobicContact CG-CD1 3.89Å; F264-L268 HydrophobicContact CZ-CD1 3.45Å; F264-L268 VanDerWaalsContact CZ-CD1 3.45Å; F264-L268 HydrophobicContact CZ-CD2 4.46Å; F264-L268 WeakPolarHBondContact O-CD1 3.32Å; F264-L268 PolarHBondContact O-N 3.17Å; T265-L268 PolarHBondContact O-N 2.84Å; Q266-L268 VanDerWaalsContact C-N 3.35Å; Q266-L268 PolarHBondContact O-N 3.29Å; L268-I271 PolarHBondContact O-N 2.88Å; L268-N272 WeakPolarHBondContact O-CB 3.32Å; L268-N272 PolarHBondContact O-N 2.94Å; L268-L324 HydrophobicContact CB-CD1 4.4Å; L268-L324 HydrophobicContact CD2-CD1 3.86Å; L268-L324 HydrophobicContact CG-CD1 4.29Å; L268-M328 HydrophobicContact CB-CE 4.02Å; L268-M328 HydrophobicContact CB-SD 3.86Å; L268-M328 HydrophobicContact CD2-CE 3.53Å; L268-M328 HydrophobicContact CD2-SD 4.48Å; L268-M328 HydrophobicContact CG-CE 4.42Å
269L93.8Very high92Very high0 Ų057.9 Ų57.90%030%0.297CS..Hα-helixtrans-63.7-41.7175.2-72.6171.8000111.6H253 A256 L257 T265 Q266 T267 N272 F273 M328 H331 H332H253-L269 PolarHBondContact CE1-O 3.3Å; A256-L269 HydrophobicContact CB-CD1 4.11Å; A256-L269 HydrophobicContact CB-CD2 4.43Å; L257-L269 HydrophobicContact CD2-CB 3.97Å; L257-L269 HydrophobicContact CD2-CD1 4.11Å; T265-L269 HydrophobicContact CG2-CD1 4.46Å; T265-L269 VanDerWaalsContact O-CG 3.31Å; T265-L269 WeakPolarHBondContact O-CG 3.4Å; T265-L269 PolarHBondContact O-N 3.38Å; Q266-L269 WeakPolarHBondContact O-CB 3.23Å; Q266-L269 PolarHBondContact O-N 3.18Å; T267-L269 VanDerWaalsContact C-N 3.33Å; T267-L269 PolarHBondContact O-N 3.41Å; L269-N272 PolarHBondContact O-N 3.47Å; L269-F273 PolarHBondContact O-N 2.99Å; L269-M328 HydrophobicContact CD2-CB 4.43Å; L269-M328 HydrophobicContact CD2-SD 4.23Å; L269-H331 HydrophobicContact CD2-CB 4.41Å; L269-H332 VanDerWaalsContact CD2-CE1 3.44Å; L269-H332 WeakPolarHBondContact CD2-CE1 3.42Å
270Y94.4Very high92.4Very high131 Ų13155.1 Ų55.151%0.51428%0.283SS..Hα-helixtrans-64.1-45.9175-73.3-60.1000112.1L257 Q266 T267 N272 F273 L274L257-Y270 HydrophobicContact CD1-CD1 4.34Å; L257-Y270 HydrophobicContact CD1-CE1 3.59Å; L257-Y270 HydrophobicContact CD2-CD2 4.44Å; L257-Y270 HydrophobicContact CD2-CE1 4.14Å; L257-Y270 HydrophobicContact CD2-CE2 4Å; Q266-Y270 HydrophobicContact CB-CE2 4.48Å; Q266-Y270 WeakPolarHBondContact O-CD2 3.36Å; Q266-Y270 PolarHBondContact O-N 3.06Å; T267-Y270 PolarHBondContact O-N 3.48Å; Y270-N272 VanDerWaalsContact C-N 3.28Å; Y270-N272 PolarHBondContact O-N 3.1Å; Y270-F273 PolarHBondContact O-N 2.93Å; Y270-L274 WeakPolarHBondContact O-CB 3.47Å; Y270-L274 PolarHBondContact O-N 2.72Å
271I94.4Very high92.7Very high78 Ų7856.8 Ų56.840%0.429%0.291SS..Hα-helixtrans-60.7-41.8176.2-63.8166000110T267 L268 F273 L274 S275 M321 L324T267-I271 VanDerWaalsContact O-CG1 3.3Å; T267-I271 WeakPolarHBondContact O-CG1 3.38Å; T267-I271 PolarHBondContact O-N 3.5Å; L268-I271 PolarHBondContact O-N 2.88Å; I271-F273 PolarHBondContact O-N 2.97Å; I271-L274 CarbonylContact O-C 3.57Å; I271-L274 PolarHBondContact O-N 3.46Å; I271-S275 PolarHBondContact O-N 3.35Å; I271-M321 HydrophobicContact CG2-SD 4.43Å; I271-L324 HydrophobicContact CB-CD2 4.18Å; I271-L324 HydrophobicContact CG2-CD2 3.57Å
272N94.4Very high92.9Very high1 Ų150.9 Ų50.91%0.00525%0.254CS..Hα-helixtrans-62.6-40.5176.717770.6000112.8L268 L269 Y270 S275 L324 R325 M328 H332L268-N272 WeakPolarHBondContact O-CB 3.32Å; L268-N272 PolarHBondContact O-N 2.94Å; L269-N272 PolarHBondContact O-N 3.47Å; Y270-N272 VanDerWaalsContact C-N 3.28Å; Y270-N272 PolarHBondContact O-N 3.1Å; N272-S275 WeakPolarHBondContact O-CB 3.41Å; N272-S275 PolarHBondContact O-N 3Å; N272-S275 PolarHBondContact O-OG 2.69Å; N272-L324 HydrophobicContact CB-CD2 4.36Å; N272-L324 HydrophobicContact CB-CG 4.36Å; N272-R325 WeakPolarHBondContact OD1-CA 3.44Å; N272-R325 VanDerWaalsContact OD1-CB 3.29Å; N272-R325 WeakPolarHBondContact OD1-CB 3.33Å; N272-R325 VanDerWaalsContact OD1-CG 3.26Å; N272-R325 WeakPolarHBondContact OD1-CG 3.46Å; N272-M328 HydrophobicContact CB-CB 4.47Å; N272-M328 HydrophobicContact CB-CG 4.1Å; N272-H332 PolarHBondContact ND2-CE1 3.44Å
273F93.6Very high92.9Very high23 Ų2348.9 Ų48.910%0.10124%0.236CC..Hα-helixtrans-68.5-37.2176.4-175.4-93.5000112A250 H253 L269 Y270 I271 S275 P276 L483A250-F273 HydrophobicContact CB-CE2 4.48Å; H253-F273 HydrophobicContact CB-CD2 3.96Å; H253-F273 AromaticContact CD2-CD2 3.46Å; H253-F273 VanDerWaalsContact CD2-CD2 3.46Å; H253-F273 WeakPolarHBondContact CD2-CD2 3.26Å; H253-F273 AromaticContact CD2-CG 3.64Å; H253-F273 AromaticContact CG-CD2 3.61Å; H253-F273 AromaticContact NE2-CG 3.71Å; L269-F273 PolarHBondContact O-N 2.99Å; Y270-F273 PolarHBondContact O-N 2.93Å; I271-F273 PolarHBondContact O-N 2.97Å; F273-S275 VanDerWaalsContact C-N 3.31Å; F273-P276 VanDerWaalsContact O-CD 3.29Å; F273-P276 WeakPolarHBondContact O-CD 3.29Å; F273-L483 HydrophobicContact CD1-CD1 4.38Å; F273-L483 HydrophobicContact CE1-CD1 3.37Å; F273-L483 HydrophobicContact CE1-CG 4.26Å; F273-L483 HydrophobicContact CE2-CD1 4.01Å; F273-L483 HydrophobicContact CE2-CD2 4.41Å; F273-L483 HydrophobicContact CE2-CG 4.04Å; F273-L483 HydrophobicContact CZ-CD1 3.15Å; F273-L483 HydrophobicContact CZ-CD2 4.3Å; F273-L483 HydrophobicContact CZ-CG 3.54Å
274L93.8Very high92.9Very high78 Ų7842 Ų4241%0.40821%0.208SC..Hα-helixtrans-80-11.1178.7-157.564.9000113.4Y270 I271 P276 L277 I278Y270-L274 WeakPolarHBondContact O-CB 3.47Å; Y270-L274 PolarHBondContact O-N 2.72Å; I271-L274 CarbonylContact O-C 3.57Å; I271-L274 PolarHBondContact O-N 3.46Å; L274-P276 VanDerWaalsContact C-CD 3.41Å; L274-P276 VanDerWaalsContact C-N 3.34Å; L274-L277 HydrophobicContact CD1-CB 4.02Å; L274-L277 HydrophobicContact CD1-CD2 3.48Å; L274-L277 VanDerWaalsContact CD1-CD2 3.48Å; L274-L277 HydrophobicContact CD1-CG 4.38Å; L274-L277 HydrophobicContact CG-CB 4.27Å; L274-L277 HydrophobicContact CG-CD2 4.15Å; L274-L277 WeakPolarHBondContact O-CA 3.29Å; L274-L277 VanDerWaalsContact O-CB 3.32Å; L274-L277 WeakPolarHBondContact O-CB 3.14Å; L274-L277 PolarHBondContact O-N 3.01Å; L274-I278 PolarHBondContact O-N 3.03Å; L274-I278 VanDerWaalsContact O-N 3.11Å
275S93.4Very high92.5Very high1 Ų136.8 Ų36.81%0.00719%0.185CC..Hα-helixtrans-53.5-41-174.589.50000114I271 N272 F273 L277 I278 M279I271-S275 PolarHBondContact O-N 3.35Å; N272-S275 WeakPolarHBondContact O-CB 3.41Å; N272-S275 PolarHBondContact O-N 3Å; N272-S275 PolarHBondContact O-OG 2.69Å; F273-S275 VanDerWaalsContact C-N 3.31Å; S275-L277 VanDerWaalsContact C-N 3.3Å; S275-L277 PolarHBondContact O-N 2.63Å; S275-I278 PolarHBondContact O-N 3.1Å; S275-M279 WeakPolarHBondContact O-CG 3.36Å; S275-M279 PolarHBondContact O-N 3.11Å; S275-M279 VanDerWaalsContact O-N 3.08Å
276P93.8Very high91.9Very high3 Ų338.6 Ų38.62%0.01920%0.198CC..Hα-helixtrans-68.8-28.5178.1-17.934.2000112.4F273 L274 V280 A472 L475 F476F273-P276 VanDerWaalsContact O-CD 3.29Å; F273-P276 WeakPolarHBondContact O-CD 3.29Å; L274-P276 VanDerWaalsContact C-CD 3.41Å; L274-P276 VanDerWaalsContact C-N 3.34Å; P276-V280 VanDerWaalsContact O-CG2 3.28Å; P276-V280 WeakPolarHBondContact O-CG2 3.43Å; P276-V280 PolarHBondContact O-N 3.02Å; P276-A472 HydrophobicContact CB-CB 4.47Å; P276-A472 WeakPolarHBondContact CB-O 3.42Å; P276-L475 HydrophobicContact CB-CB 4.13Å; P276-L475 HydrophobicContact CG-CB 4.23Å; P276-F476 HydrophobicContact CB-CB 4.05Å
277L94.3Very high91.2Very high44 Ų4440.1 Ų40.123%0.2321%0.207CC..Hα-helixtrans-67.8-46.8172.8179.665.1000110.7L274 S275 M279 V280 L281 F476L274-L277 HydrophobicContact CD1-CB 4.02Å; L274-L277 HydrophobicContact CD1-CD2 3.48Å; L274-L277 VanDerWaalsContact CD1-CD2 3.48Å; L274-L277 HydrophobicContact CD1-CG 4.38Å; L274-L277 HydrophobicContact CG-CB 4.27Å; L274-L277 HydrophobicContact CG-CD2 4.15Å; L274-L277 WeakPolarHBondContact O-CA 3.29Å; L274-L277 VanDerWaalsContact O-CB 3.32Å; L274-L277 WeakPolarHBondContact O-CB 3.14Å; L274-L277 PolarHBondContact O-N 3.01Å; S275-L277 VanDerWaalsContact C-N 3.3Å; S275-L277 PolarHBondContact O-N 2.63Å; L277-M279 PolarHBondContact O-N 3.11Å; L277-V280 PolarHBondContact O-N 2.76Å; L277-L281 HydrophobicContact CD1-CD1 4.39Å; L277-L281 HydrophobicContact CD1-CD2 4.49Å; L277-L281 HydrophobicContact CD1-CG 4.22Å; L277-L281 HydrophobicContact CG-CD1 4.02Å; L277-L281 HydrophobicContact CG-CG 4.27Å; L277-L281 VanDerWaalsContact O-CG 3.31Å; L277-L281 WeakPolarHBondContact O-CG 3.47Å; L277-L281 PolarHBondContact O-N 3.29Å; L277-F476 HydrophobicContact CB-CD2 3.81Å; L277-F476 HydrophobicContact CB-CE2 3.77Å; L277-F476 HydrophobicContact CB-CG 4.3Å; L277-F476 HydrophobicContact CB-CZ 4.23Å; L277-F476 HydrophobicContact CD1-CD1 4.21Å; L277-F476 HydrophobicContact CD1-CE1 3.86Å; L277-F476 HydrophobicContact CD1-CE2 4.34Å; L277-F476 HydrophobicContact CD1-CZ 3.93Å; L277-F476 HydrophobicContact CD2-CE2 4.27Å; L277-F476 HydrophobicContact CD2-CZ 4.16Å; L277-F476 HydrophobicContact CG-CE2 4.34Å; L277-F476 HydrophobicContact CG-CZ 4.33Å
278I93.1Very high90.5Very high53 Ų5338.5 Ų38.527%0.27220%0.197SC..Hα-helixtrans-56-43.9178.2-61.7170.2000109.7L274 S275 L281 L282 V317 M321L274-I278 PolarHBondContact O-N 3.03Å; L274-I278 VanDerWaalsContact O-N 3.11Å; S275-I278 PolarHBondContact O-N 3.1Å; I278-L281 PolarHBondContact O-N 3.3Å; I278-L282 WeakPolarHBondContact O-CG 3.49Å; I278-L282 PolarHBondContact O-N 2.64Å; I278-V317 HydrophobicContact CG2-CG1 4.37Å; I278-M321 HydrophobicContact CD1-CE 3.72Å; I278-M321 HydrophobicContact CG2-CE 4.21Å
279M92.8Very high89.6Confident6 Ų637.7 Ų37.73%0.0319%0.192CC..Hα-helixtrans-60.7-45.2174.8-66.9165.6-179.700112.8S275 L277 L281 L282 W283 I318 M321 L384 A472S275-M279 WeakPolarHBondContact O-CG 3.36Å; S275-M279 PolarHBondContact O-N 3.11Å; S275-M279 VanDerWaalsContact O-N 3.08Å; L277-M279 PolarHBondContact O-N 3.11Å; M279-L281 VanDerWaalsContact C-N 3.3Å; M279-L281 PolarHBondContact O-N 3.38Å; M279-L282 PolarHBondContact O-N 3.45Å; M279-W283 WeakPolarHBondContact O-CZ3 3.46Å; M279-I318 HydrophobicContact CE-CG2 4.22Å; M279-I318 HydrophobicContact CG-CG1 4.14Å; M279-M321 HydrophobicContact CE-CB 3.26Å; M279-M321 HydrophobicContact CE-CG 4.05Å; M279-L384 HydrophobicContact CE-CD2 3.57Å; M279-L384 HydrophobicContact SD-CD2 3.45Å; M279-L384 WeakPolarHBondContact SD-CD2 3.05Å; M279-A472 HydrophobicContact CB-CB 3.81Å; M279-A472 HydrophobicContact SD-CB 4.09Å
280V93.5Very high88.7Confident19 Ų1941.1 Ų41.112%0.11521%0.21CC..Hα-helixtrans-62-39.6178.8164.50000111.7P276 L277 L282 W283 W469 A472 A473P276-V280 VanDerWaalsContact O-CG2 3.28Å; P276-V280 WeakPolarHBondContact O-CG2 3.43Å; P276-V280 PolarHBondContact O-N 3.02Å; L277-V280 PolarHBondContact O-N 2.76Å; V280-L282 VanDerWaalsContact C-N 3.33Å; V280-L282 PolarHBondContact O-N 3.03Å; V280-W283 PolarHBondContact O-N 2.85Å; V280-W469 HydrophobicContact CG1-CZ2 3.94Å; V280-W469 PolarHBondContact O-NE1 3.24Å; V280-A472 HydrophobicContact CG2-CB 3.99Å; V280-A473 HydrophobicContact CG2-CB 3.76Å
281L91.8Very high87.8Confident59 Ų5942 Ų4231%0.30921%0.213SC..Hα-helixtrans-66.5-32.7-177.8-67.5175.4000112.7L277 I278 M279 W283 V284 I287 T288L277-L281 HydrophobicContact CD1-CD1 4.39Å; L277-L281 HydrophobicContact CD1-CD2 4.49Å; L277-L281 HydrophobicContact CD1-CG 4.22Å; L277-L281 HydrophobicContact CG-CD1 4.02Å; L277-L281 HydrophobicContact CG-CG 4.27Å; L277-L281 VanDerWaalsContact O-CG 3.31Å; L277-L281 WeakPolarHBondContact O-CG 3.47Å; L277-L281 PolarHBondContact O-N 3.29Å; I278-L281 PolarHBondContact O-N 3.3Å; M279-L281 VanDerWaalsContact C-N 3.3Å; M279-L281 PolarHBondContact O-N 3.38Å; L281-W283 PolarHBondContact O-N 2.86Å; L281-W283 VanDerWaalsContact O-N 3.07Å; L281-V284 WeakPolarHBondContact O-CB 3.28Å; L281-V284 PolarHBondContact O-N 2.91Å; L281-I287 HydrophobicContact CD2-CD1 3.77Å; L281-T288 PolarHBondContact O-OG1 3.3Å
282L90.3Very high86.7Confident13 Ų1340.1 Ų40.17%0.06820%0.204CC..THydrogen-bonded Turntrans-58.6-21.4178.8-73.5170.5000114.4I278 M279 V280 T288 Y310 R314 V317I278-L282 WeakPolarHBondContact O-CG 3.49Å; I278-L282 PolarHBondContact O-N 2.64Å; M279-L282 PolarHBondContact O-N 3.45Å; V280-L282 VanDerWaalsContact C-N 3.33Å; V280-L282 PolarHBondContact O-N 3.03Å; L282-T288 HydrophobicContact CD2-CG2 4.41Å; L282-Y310 PolarHBondContact O-OH 2.95Å; L282-R314 HydrophobicContact CB-CG 4.25Å; L282-R314 PolarHBondContact O-NE 3.45Å; L282-R314 PolarHBondContact O-NH2 2.93Å; L282-V317 HydrophobicContact CD1-CB 4.03Å; L282-V317 HydrophobicContact CD1-CG1 3.81Å
283W91.1Very high85.5Confident5 Ų541.1 Ų41.12%0.01921%0.209CC..THydrogen-bonded Turntrans-94.2-6.4176.8-84.2-101.7000113.5E193 F194 M279 V280 L281 K285 R314 I318 L391 S465 T468 W469E193-W283 PolarHBondContact N-O 3.33Å; E193-W283 VanDerWaalsContact O-CD1 3.27Å; F194-W283 AromaticContact CD1-CD1 3.72Å; F194-W283 HydrophobicContact CD1-CG 4.46Å; F194-W283 HydrophobicContact CE1-CB 4.15Å; F194-W283 AromaticContact CE1-CD1 3.91Å; F194-W283 HydrophobicContact CE1-CG 4.23Å; M279-W283 WeakPolarHBondContact O-CZ3 3.46Å; V280-W283 PolarHBondContact O-N 2.85Å; L281-W283 PolarHBondContact O-N 2.86Å; L281-W283 VanDerWaalsContact O-N 3.07Å; W283-K285 PolarHBondContact O-N 3.49Å; W283-R314 HydrophobicContact CH2-CB 4.13Å; W283-I318 HydrophobicContact CH2-CD1 3.45Å; W283-I318 VanDerWaalsContact CH2-CD1 3.45Å; W283-I318 HydrophobicContact CH2-CG1 4.49Å; W283-I318 HydrophobicContact CZ3-CD1 3.98Å; W283-L391 HydrophobicContact CZ2-CD2 4.3Å; W283-S465 PolarHBondContact NE1-OG 2.96Å; W283-T468 HydrophobicContact CH2-CG2 4.46Å; W283-W469 VanDerWaalsContact CB-CD1 3.49Å; W283-W469 HydrophobicContact CB-CG 4.33Å; W283-W469 HydrophobicContact CD2-CB 4.46Å; W283-W469 HydrophobicContact CG-CB 4.39Å; W283-W469 AromaticContact CG-CD1 3.84Å; W283-W469 HydrophobicContact CG-CG 4.39Å
284V89.5Confident84.1Confident25 Ų2544.4 Ų44.415%0.15223%0.228CC..BIsolated β-bridgetrans-86.1105176.6-172.40000108.5L192 L281 P286 I287 T288L192-V284 HydrophobicContact CD2-CG2 3.87Å; L281-V284 WeakPolarHBondContact O-CB 3.28Å; L281-V284 PolarHBondContact O-N 2.91Å; V284-P286 HydrophobicContact CG1-CG 3.87Å; V284-I287 HydrophobicContact CB-CB 4.21Å; V284-I287 HydrophobicContact CB-CD1 4Å; V284-I287 HydrophobicContact CB-CG1 4.21Å; V284-I287 HydrophobicContact CG1-CB 4.13Å; V284-I287 HydrophobicContact CG1-CD1 3.59Å; V284-I287 HydrophobicContact CG1-CG1 3.67Å; V284-I287 HydrophobicContact CG2-CD1 4.41Å; V284-I287 PolarHBondContact O-N 3.42Å; V284-T288 PolarHBondContact O-N 2.98Å; V284-T288 PolarHBondContact O-OG1 2.87Å; V284-T288 VanDerWaalsContact O-OG1 3.06Å
285K83.8Confident82.7Confident42 Ų4242.3 Ų42.318%0.18322%0.219CC..Iπ-helixtrans-51.9-53.6-178.1-72.7-173.4174.2172.70113.5E189 N190 Y191 E193 W283 I287 T288 K289 D290E189-K285 VanDerWaalsContact O-CE 3.24Å; E189-K285 WeakPolarHBondContact O-CE 3.34Å; E189-K285 PolarHBondContact O-NZ 3.38Å; N190-K285 WeakPolarHBondContact O-CD 3.48Å; Y191-K285 PolarHBondContact O-N 2.82Å; E193-K285 HydrophobicContact CB-CD 4.22Å; E193-K285 VanDerWaalsContact CB-CE 3.43Å; E193-K285 HydrophobicContact CB-CG 3.85Å; E193-K285 VanDerWaalsContact CD-CE 3.48Å; E193-K285 WeakPolarHBondContact OE1-CE 3.21Å; W283-K285 PolarHBondContact O-N 3.49Å; K285-I287 PolarHBondContact O-N 2.78Å; K285-I287 VanDerWaalsContact O-N 3.14Å; K285-T288 PolarHBondContact O-N 3.32Å; K285-K289 HydrophobicContact CB-CB 4.49Å; K285-K289 HydrophobicContact CG-CB 4.49Å; K285-K289 PolarHBondContact O-N 3.43Å; K285-D290 PolarHBondContact O-N 3.15Å
286P76.4Confident80.9Confident67 Ų6748.7 Ų48.744%0.43526%0.258SS..Iπ-helixtrans-66.6-21.1-175.125-35.8000114.2Y191 V284 D290Y191-P286 HydrophobicContact CD1-CG 4.45Å; V284-P286 HydrophobicContact CG1-CG 3.87Å; P286-D290 VanDerWaalsContact CA-OD2 3.32Å; P286-D290 WeakPolarHBondContact CA-OD2 3.24Å
287I78.4Confident79.1Confident90 Ų9055.9 Ų55.946%0.46230%0.295SS..Iπ-helixtrans-86.7-39.9-177.8-63.6178.7000111.2L281 V284 K285L281-I287 HydrophobicContact CD2-CD1 3.77Å; V284-I287 HydrophobicContact CB-CB 4.21Å; V284-I287 HydrophobicContact CB-CD1 4Å; V284-I287 HydrophobicContact CB-CG1 4.21Å; V284-I287 HydrophobicContact CG1-CB 4.13Å; V284-I287 HydrophobicContact CG1-CD1 3.59Å; V284-I287 HydrophobicContact CG1-CG1 3.67Å; V284-I287 HydrophobicContact CG2-CD1 4.41Å; V284-I287 PolarHBondContact O-N 3.42Å; K285-I287 PolarHBondContact O-N 2.78Å; K285-I287 VanDerWaalsContact O-N 3.14Å
288T78.5Confident77.2Confident36 Ų3656.2 Ų56.222%0.22131%0.309CS..Iπ-helixtrans-120.3-57.2-170.719.20000112.9L281 L282 V284 K285 Y291 L292 Y310L281-T288 PolarHBondContact O-OG1 3.3Å; L282-T288 HydrophobicContact CD2-CG2 4.41Å; V284-T288 PolarHBondContact O-N 2.98Å; V284-T288 PolarHBondContact O-OG1 2.87Å; V284-T288 VanDerWaalsContact O-OG1 3.06Å; K285-T288 PolarHBondContact O-N 3.32Å; T288-Y291 PolarHBondContact O-N 3.29Å; T288-L292 VanDerWaalsContact O-CB 3.25Å; T288-L292 WeakPolarHBondContact O-CB 3.34Å; T288-L292 PolarHBondContact O-N 2.84Å; T288-Y310 WeakPolarHBondContact CB-OH 3.49Å; T288-Y310 PolarHBondContact OG1-OH 3.47Å
289K75.9Confident75.3Confident18 Ų1864.2 Ų64.28%0.07834%0.342CS..Iπ-helixtrans-64.8-51.2-173.4-168.1171.7167.9167.40111E193 K285 Y291 L292 L293 E307 Y310E193-K289 WeakPolarHBondContact OE1-CD 3.3Å; E193-K289 IonicContact OE1-NZ 2.88Å; E193-K289 PolarHBondContact OE1-NZ 3.48Å; E193-K289 WeakPolarHBondContact OE2-CD 3.39Å; E193-K289 IonicContact OE2-NZ 2.76Å; K285-K289 HydrophobicContact CB-CB 4.49Å; K285-K289 HydrophobicContact CG-CB 4.49Å; K285-K289 PolarHBondContact O-N 3.43Å; K289-Y291 VanDerWaalsContact C-N 3.32Å; K289-Y291 PolarHBondContact O-N 3.33Å; K289-L292 PolarHBondContact O-N 3.46Å; K289-L293 HydrophobicContact CB-CD1 4.37Å; K289-L293 HydrophobicContact CD-CD1 4.02Å; K289-L293 HydrophobicContact CG-CD1 3.2Å; K289-L293 WeakPolarHBondContact O-CB 3.31Å; K289-L293 WeakPolarHBondContact O-CD1 3.44Å; K289-L293 PolarHBondContact O-N 2.88Å; K289-E307 WeakPolarHBondContact CE-OE1 3.5Å; K289-E307 IonicContact NZ-OE1 3.78Å; K289-E307 PolarHBondContact NZ-OE1 3.11Å; K289-Y310 HydrophobicContact CB-CD1 4.48Å; K289-Y310 HydrophobicContact CB-CE1 3.8Å; K289-Y310 HydrophobicContact CD-CD1 4.23Å; K289-Y310 HydrophobicContact CD-CE1 4.15Å; K289-Y310 HydrophobicContact CG-CD1 4.09Å; K289-Y310 HydrophobicContact CG-CE1 3.89Å
290D76.4Confident73.5Confident71 Ų7172 Ų7238%0.3838%0.379SS..Hα-helixtrans-67.8-35.3-177.4-61-23.1000111.5K285 P286 N294K285-D290 PolarHBondContact O-N 3.15Å; P286-D290 VanDerWaalsContact CA-OD2 3.32Å; P286-D290 WeakPolarHBondContact CA-OD2 3.24Å; D290-N294 CarbonylContact O-C 3.27Å; D290-N294 VanDerWaalsContact O-C 3.27Å; D290-N294 WeakPolarHBondContact O-CA 3.41Å; D290-N294 WeakPolarHBondContact O-CB 3.32Å; D290-N294 PolarHBondContact O-N 3.16Å; D290-N294 VanDerWaalsContact O-O 3.08Å
291Y73.8Confident71.6Confident149 Ų14974.9 Ų74.958%0.58440%0.399SS*.Hα-helixtrans-65.5-38.6174.9-174.3-97000112.7T288 K289T288-Y291 PolarHBondContact O-N 3.29Å; K289-Y291 VanDerWaalsContact C-N 3.32Å; K289-Y291 PolarHBondContact O-N 3.33Å
292L71.1Confident70.1Confident40 Ų4077 Ų7721%0.20941%0.414CS..Hα-helixtrans-85.2-37.1-175.1-159.171.1000113.1T288 K289 L304 M305 Y310T288-L292 VanDerWaalsContact O-CB 3.25Å; T288-L292 WeakPolarHBondContact O-CB 3.34Å; T288-L292 PolarHBondContact O-N 2.84Å; K289-L292 PolarHBondContact O-N 3.46Å; L292-L304 HydrophobicContact CD1-CB 4.43Å; L292-L304 HydrophobicContact CD1-CD2 3.51Å; L292-L304 HydrophobicContact CG-CB 4.47Å; L292-L304 HydrophobicContact CG-CD2 4.29Å; L292-L304 WeakPolarHBondContact O-CB 3.44Å; L292-L304 PolarHBondContact O-N 3.01Å; L292-M305 HydrophobicContact CD2-CB 4.29Å; L292-M305 HydrophobicContact CD2-CE 3.68Å; L292-Y310 HydrophobicContact CD2-CD2 3.82Å; L292-Y310 HydrophobicContact CD2-CE2 4.24Å
293L69.1Low69.1Low22 Ų2280 Ų8012%0.11544%0.435CS..Hα-helixtrans-86.1-30.8179.2-78.9130.7000112.8K289 P303 M305 E307K289-L293 HydrophobicContact CB-CD1 4.37Å; K289-L293 HydrophobicContact CD-CD1 4.02Å; K289-L293 HydrophobicContact CG-CD1 3.2Å; K289-L293 WeakPolarHBondContact O-CB 3.31Å; K289-L293 WeakPolarHBondContact O-CD1 3.44Å; K289-L293 PolarHBondContact O-N 2.88Å; L293-P303 VanDerWaalsContact O-CA 3.28Å; L293-P303 WeakPolarHBondContact O-CA 3.33Å; L293-P303 WeakPolarHBondContact O-CB 3.27Å; L293-M305 WeakPolarHBondContact CD2-O 3.33Å; L293-E307 HydrophobicContact CD2-CG 4.06Å
294N65.7Low67.9Low92 Ų9286 Ų8649%0.49247%0.467SS..SBendtrans-13169.8179.5-65.9-50000110D290 T296D290-N294 CarbonylContact O-C 3.27Å; D290-N294 VanDerWaalsContact O-C 3.27Å; D290-N294 WeakPolarHBondContact O-CA 3.41Å; D290-N294 WeakPolarHBondContact O-CB 3.32Å; D290-N294 PolarHBondContact O-N 3.16Å; D290-N294 VanDerWaalsContact O-O 3.08Å; N294-T296 PolarHBondContact O-N 3.01Å
295P63.5Low67.2Low34 Ų3487.1 Ų87.122%0.22147%0.471CS..  trans-61108.4177.125.5-32.4000108.5L297P295-L297 PolarHBondContact O-N 2.93Å
296T56.7Low67.1Low135 Ų13587.7 Ų87.783%0.82848%0.48SS*.THydrogen-bonded Turntrans-69.814.5178.850.80000113N294N294-T296 PolarHBondContact O-N 3.01Å
297L56.3Low67.3Low153 Ų15390.1 Ų90.180%0.80149%0.486SS*.THydrogen-bonded Turntrans-92.46.8-168.8-135.682000114.4P295P295-L297 PolarHBondContact O-N 2.93Å
298G52.6Low67.4Low51 Ų5189.5 Ų89.553%0.52648%0.481SS..SBendtrans-163.1164.4-179.900000114.5E300G298-E300 PolarHBondContact O-N 3.25Å
299K54.9Low67.6Low221 Ų22188.3 Ų88.396%0.96147%0.474SS*.SBendtrans-71-8.2178.4-73.4-176.9177.9179.30113.9
300E54Low68.1Low171 Ų17187.6 Ų87.680%0.79947%0.471SS*.SBendtrans-126.8101.1173.4-68.3-178.8173.700107.9G298 V302G298-E300 PolarHBondContact O-N 3.25Å; E300-V302 VanDerWaalsContact C-N 3.33Å; E300-V302 PolarHBondContact O-N 3.03Å
301S53.6Low68.6Low78 Ų7885 Ų8555%0.54546%0.457SS..  trans-80.582.317650.80000109.5
302V60.8Low69.4Low103 Ų10378.1 Ų78.162%0.62443%0.431SS*.  trans-77.4123.4166.2-178.10000107.7E300 L304E300-V302 VanDerWaalsContact C-N 3.33Å; E300-V302 PolarHBondContact O-N 3.03Å; V302-L304 PolarHBondContact O-N 3.27Å
303P68Low70.3Confident76 Ų7679.4 Ų79.449%0.49444%0.438SS..  trans-62.8124.8176.825.3-32.5000109.7L293 M305L293-P303 VanDerWaalsContact O-CA 3.28Å; L293-P303 WeakPolarHBondContact O-CA 3.33Å; L293-P303 WeakPolarHBondContact O-CB 3.27Å; P303-M305 PolarHBondContact O-N 2.86Å
304L67.6Low71.3Confident133 Ų13378.9 Ų78.970%0.69643%0.434SS*.SBendtrans-67.6-25.5-177.7-157.9101.9000111.7L292 V302L292-L304 HydrophobicContact CD1-CB 4.43Å; L292-L304 HydrophobicContact CD1-CD2 3.51Å; L292-L304 HydrophobicContact CG-CB 4.47Å; L292-L304 HydrophobicContact CG-CD2 4.29Å; L292-L304 WeakPolarHBondContact O-CB 3.44Å; L292-L304 PolarHBondContact O-N 3.01Å; V302-L304 PolarHBondContact O-N 3.27Å
305M74.1Confident72.6Confident48 Ų4874.6 Ų74.624%0.23641%0.411CS..SBendtrans-155.9148.2-176.7-165.8157.679.100111.6L292 L293 P303 A309 Y310 L313L292-M305 HydrophobicContact CD2-CB 4.29Å; L292-M305 HydrophobicContact CD2-CE 3.68Å; L293-M305 WeakPolarHBondContact CD2-O 3.33Å; P303-M305 PolarHBondContact O-N 2.86Å; M305-A309 VanDerWaalsContact CE-C 3.45Å; M305-A309 HydrophobicContact CE-CB 4.34Å; M305-A309 WeakPolarHBondContact CE-O 3.31Å; M305-A309 HydrophobicContact CG-CB 3.29Å; M305-A309 HydrophobicContact SD-CB 3.7Å; M305-Y310 HydrophobicContact CE-CD2 3.93Å; M305-Y310 HydrophobicContact CE-CG 4.37Å; M305-Y310 VanDerWaalsContact CE-N 3.32Å; M305-L313 HydrophobicContact CE-CB 3.91Å; M305-L313 HydrophobicContact CE-CD2 3.64Å; M305-L313 HydrophobicContact CE-CG 4.39Å
306S81.1Confident74Confident54 Ų5479.1 Ų79.138%0.37842%0.424SS..  trans-73.5161.6174.569.50000112.2Q308 A309 Y310S306-Q308 VanDerWaalsContact C-N 3.32Å; S306-Q308 PolarHBondContact O-N 3.3Å; S306-A309 PolarHBondContact O-N 3.22Å; S306-A309 WeakPolarHBondContact OG-CB 3.47Å; S306-A309 PolarHBondContact OG-N 3.2Å; S306-Y310 PolarHBondContact O-N 3.43Å
307E81Confident75.8Confident118 Ų11874 Ų7455%0.55139%0.393SS*.Hα-helixtrans-61.2-39.8179-63-155.2131.500112.6K289 L293 A309 Y310 D311K289-E307 WeakPolarHBondContact CE-OE1 3.5Å; K289-E307 IonicContact NZ-OE1 3.78Å; K289-E307 PolarHBondContact NZ-OE1 3.11Å; L293-E307 HydrophobicContact CD2-CG 4.06Å; E307-A309 VanDerWaalsContact C-N 3.35Å; E307-A309 PolarHBondContact O-N 3.47Å; E307-Y310 WeakPolarHBondContact O-CB 3.46Å; E307-Y310 PolarHBondContact O-N 3.21Å; E307-D311 PolarHBondContact O-N 3.01Å
308Q80.1Confident77.6Confident77 Ų7766.7 Ų66.736%0.3636%0.355SS..Hα-helixtrans-66.5-37.9178-174.5175.92.300112.2S306 Y310 D311 S312 S398S306-Q308 VanDerWaalsContact C-N 3.32Å; S306-Q308 PolarHBondContact O-N 3.3Å; Q308-Y310 VanDerWaalsContact C-N 3.31Å; Q308-D311 PolarHBondContact O-N 2.89Å; Q308-S312 PolarHBondContact O-N 3.04Å; Q308-S312 PolarHBondContact O-OG 2.63Å; Q308-S398 PolarHBondContact NE2-OG 3.26Å
309A83.9Confident79.7Confident10 Ų1065.9 Ų65.98%0.08334%0.338CS..Hα-helixtrans-67.6-34175.600000111.7M305 S306 E307 S312 L313 V401M305-A309 VanDerWaalsContact CE-C 3.45Å; M305-A309 HydrophobicContact CE-CB 4.34Å; M305-A309 WeakPolarHBondContact CE-O 3.31Å; M305-A309 HydrophobicContact CG-CB 3.29Å; M305-A309 HydrophobicContact SD-CB 3.7Å; S306-A309 PolarHBondContact O-N 3.22Å; S306-A309 WeakPolarHBondContact OG-CB 3.47Å; S306-A309 PolarHBondContact OG-N 3.2Å; E307-A309 VanDerWaalsContact C-N 3.35Å; E307-A309 PolarHBondContact O-N 3.47Å; A309-S312 PolarHBondContact O-N 2.97Å; A309-L313 WeakPolarHBondContact O-CB 3.33Å; A309-L313 PolarHBondContact O-N 2.89Å; A309-V401 HydrophobicContact CB-CB 4.47Å; A309-V401 HydrophobicContact CB-CG1 4.04Å; A309-V401 HydrophobicContact CB-CG2 3.55Å
310Y86.6Confident81.6Confident3 Ų360.7 Ų60.71%0.01232%0.32CS..Hα-helixtrans-66.5-44173.4-173.9-115.9000113.6L282 T288 K289 L292 M305 S306 E307 Q308 S312 L313 R314L282-Y310 PolarHBondContact O-OH 2.95Å; T288-Y310 WeakPolarHBondContact CB-OH 3.49Å; T288-Y310 PolarHBondContact OG1-OH 3.47Å; K289-Y310 HydrophobicContact CB-CD1 4.48Å; K289-Y310 HydrophobicContact CB-CE1 3.8Å; K289-Y310 HydrophobicContact CD-CD1 4.23Å; K289-Y310 HydrophobicContact CD-CE1 4.15Å; K289-Y310 HydrophobicContact CG-CD1 4.09Å; K289-Y310 HydrophobicContact CG-CE1 3.89Å; L292-Y310 HydrophobicContact CD2-CD2 3.82Å; L292-Y310 HydrophobicContact CD2-CE2 4.24Å; M305-Y310 HydrophobicContact CE-CD2 3.93Å; M305-Y310 HydrophobicContact CE-CG 4.37Å; M305-Y310 VanDerWaalsContact CE-N 3.32Å; S306-Y310 PolarHBondContact O-N 3.43Å; E307-Y310 WeakPolarHBondContact O-CB 3.46Å; E307-Y310 PolarHBondContact O-N 3.21Å; Q308-Y310 VanDerWaalsContact C-N 3.31Å; Y310-S312 VanDerWaalsContact C-N 3.31Å; Y310-S312 PolarHBondContact O-N 3.31Å; Y310-L313 HydrophobicContact CD2-CD2 4.33Å; Y310-L313 WeakPolarHBondContact O-CB 3.26Å; Y310-L313 PolarHBondContact O-N 2.88Å; Y310-R314 HydrophobicContact CE1-CG 4.46Å; Y310-R314 WeakPolarHBondContact O-CG 3.28Å; Y310-R314 PolarHBondContact O-N 3.41Å
311D86.8Confident83.5Confident16 Ų1653.5 Ų53.59%0.08629%0.287CS..Hα-helixtrans-64.3-37.6175.4-77.3-15.1000112.1E307 Q308 R314 L315 H397 R461E307-D311 PolarHBondContact O-N 3.01Å; Q308-D311 PolarHBondContact O-N 2.89Å; D311-R314 PolarHBondContact O-N 3.29Å; D311-R314 IonicContact OD1-CZ 2.89Å; D311-R314 IonicContact OD1-NH1 2.79Å; D311-R314 PolarHBondContact OD1-NH1 3.29Å; D311-L315 WeakPolarHBondContact O-CG 3.44Å; D311-L315 PolarHBondContact O-N 3.3Å; D311-H397 IonicContact OD2-CE1 3.72Å; D311-H397 PolarHBondContact OD2-CE1 3.38Å; D311-H397 VanDerWaalsContact OD2-CE1 3.22Å; D311-H397 IonicContact OD2-ND1 3.07Å; D311-R461 IonicContact OD2-CZ 2.68Å; D311-R461 IonicContact OD2-NH2 2.74Å; D311-R461 PolarHBondContact OD2-NH2 3.41Å
312S89.2Confident85.5Confident5 Ų550 Ų504%0.03526%0.262CS..Hα-helixtrans-64.6-43.2173.9-54.90000111.8Q308 A309 Y310 R314 L315 W316 S398Q308-S312 PolarHBondContact O-N 3.04Å; Q308-S312 PolarHBondContact O-OG 2.63Å; A309-S312 PolarHBondContact O-N 2.97Å; Y310-S312 VanDerWaalsContact C-N 3.31Å; Y310-S312 PolarHBondContact O-N 3.31Å; S312-R314 VanDerWaalsContact C-N 3.34Å; S312-R314 PolarHBondContact O-N 3.23Å; S312-L315 PolarHBondContact O-N 3.32Å; S312-W316 VanDerWaalsContact O-CD1 3.3Å; S312-W316 PolarHBondContact O-N 3.24Å; S312-W316 VanDerWaalsContact O-N 3.1Å; S312-S398 PolarHBondContact OG-O 3.5Å; S312-S398 VanDerWaalsContact OG-O 3.08Å
313L90.1Very high87.1Confident68 Ų6849.1 Ų49.136%0.35626%0.256SS..Hα-helixtrans-58.6-44.8176.6176.670.7000111.3M305 A309 Y310 L315 W316 V317M305-L313 HydrophobicContact CE-CB 3.91Å; M305-L313 HydrophobicContact CE-CD2 3.64Å; M305-L313 HydrophobicContact CE-CG 4.39Å; A309-L313 WeakPolarHBondContact O-CB 3.33Å; A309-L313 PolarHBondContact O-N 2.89Å; Y310-L313 HydrophobicContact CD2-CD2 4.33Å; Y310-L313 WeakPolarHBondContact O-CB 3.26Å; Y310-L313 PolarHBondContact O-N 2.88Å; L313-L315 VanDerWaalsContact C-N 3.3Å; L313-L315 PolarHBondContact O-N 3.45Å; L313-W316 PolarHBondContact O-N 3.03Å; L313-V317 HydrophobicContact CD1-CG2 4.02Å; L313-V317 HydrophobicContact CG-CG2 4.18Å; L313-V317 VanDerWaalsContact O-CG2 3.29Å; L313-V317 WeakPolarHBondContact O-CG2 3.34Å; L313-V317 PolarHBondContact O-N 3.38Å
314R91.4Very high88.4Confident10 Ų1047 Ų474%0.03824%0.241CC..Hα-helixtrans-54.3-47.4178.2-73.9173.7162.3156.4-11.3111.6E193 L282 W283 Y310 D311 S312 V317 I318E193-R314 IonicContact OE2-CZ 3.22Å; E193-R314 IonicContact OE2-NH1 2.63Å; E193-R314 PolarHBondContact OE2-NH1 3.04Å; E193-R314 IonicContact OE2-NH2 3.6Å; E193-R314 PolarHBondContact OE2-NH2 2.99Å; L282-R314 HydrophobicContact CB-CG 4.25Å; L282-R314 PolarHBondContact O-NE 3.45Å; L282-R314 PolarHBondContact O-NH2 2.93Å; W283-R314 HydrophobicContact CH2-CB 4.13Å; Y310-R314 HydrophobicContact CE1-CG 4.46Å; Y310-R314 WeakPolarHBondContact O-CG 3.28Å; Y310-R314 PolarHBondContact O-N 3.41Å; D311-R314 PolarHBondContact O-N 3.29Å; D311-R314 IonicContact OD1-CZ 2.89Å; D311-R314 IonicContact OD1-NH1 2.79Å; D311-R314 PolarHBondContact OD1-NH1 3.29Å; S312-R314 VanDerWaalsContact C-N 3.34Å; S312-R314 PolarHBondContact O-N 3.23Å; R314-V317 PolarHBondContact O-N 3.38Å; R314-I318 WeakPolarHBondContact O-CG1 3.42Å; R314-I318 PolarHBondContact O-N 2.98Å; R314-I318 VanDerWaalsContact O-N 3.1Å
315L92.8Very high89.6Confident2 Ų241 Ų411%0.0121%0.209CC..Hα-helixtrans-64.4-45-179.9-60174.2000111.6D311 S312 L313 I318 I319 T388 L391 K392 H397 W399D311-L315 WeakPolarHBondContact O-CG 3.44Å; D311-L315 PolarHBondContact O-N 3.3Å; S312-L315 PolarHBondContact O-N 3.32Å; L313-L315 VanDerWaalsContact C-N 3.3Å; L313-L315 PolarHBondContact O-N 3.45Å; L315-I318 PolarHBondContact O-N 2.98Å; L315-I319 WeakPolarHBondContact O-CG1 3.13Å; L315-I319 PolarHBondContact O-N 3.27Å; L315-T388 HydrophobicContact CB-CG2 4.44Å; L315-T388 HydrophobicContact CD2-CG2 3.62Å; L315-L391 HydrophobicContact CD2-CD2 3.99Å; L315-L391 HydrophobicContact CD2-CG 4.21Å; L315-K392 HydrophobicContact CD1-CB 3.87Å; L315-K392 HydrophobicContact CD1-CG 3.92Å; L315-H397 HydrophobicContact CD1-CB 3.74Å; L315-W399 HydrophobicContact CB-CE3 4.31Å; L315-W399 HydrophobicContact CB-CH2 4.31Å; L315-W399 HydrophobicContact CB-CZ3 3.65Å; L315-W399 HydrophobicContact CD1-CZ3 4.38Å
316W93.4Very high90.5Very high130 Ų13042.1 Ų42.149%0.49222%0.215SC..Hα-helixtrans-63.2-42177.4-84113.6000113S312 L313 I318 I319 L320 W399S312-W316 VanDerWaalsContact O-CD1 3.3Å; S312-W316 PolarHBondContact O-N 3.24Å; S312-W316 VanDerWaalsContact O-N 3.1Å; L313-W316 PolarHBondContact O-N 3.03Å; W316-I318 VanDerWaalsContact C-N 3.31Å; W316-I318 PolarHBondContact O-N 3.31Å; W316-I319 PolarHBondContact O-N 3.15Å; W316-L320 WeakPolarHBondContact O-CB 3.2Å; W316-L320 PolarHBondContact O-N 3.5Å; W316-W399 HydrophobicContact CZ2-CB 4.47Å; W316-W399 HydrophobicContact CZ2-CE3 4.39Å; W316-W399 PolarHBondContact NE1-O 3.38Å
317V93.9Very high91.1Very high27 Ų2742.3 Ų42.316%0.16422%0.221CC..Hα-helixtrans-61.8-41.6176.5173.20000110.4I278 L282 L313 R314 L320 M321I278-V317 HydrophobicContact CG2-CG1 4.37Å; L282-V317 HydrophobicContact CD1-CB 4.03Å; L282-V317 HydrophobicContact CD1-CG1 3.81Å; L313-V317 HydrophobicContact CD1-CG2 4.02Å; L313-V317 HydrophobicContact CG-CG2 4.18Å; L313-V317 VanDerWaalsContact O-CG2 3.29Å; L313-V317 WeakPolarHBondContact O-CG2 3.34Å; L313-V317 PolarHBondContact O-N 3.38Å; R314-V317 PolarHBondContact O-N 3.38Å; V317-L320 PolarHBondContact O-N 3.1Å; V317-M321 HydrophobicContact CG1-CE 4.42Å; V317-M321 HydrophobicContact CG1-CG 4.3Å; V317-M321 WeakPolarHBondContact O-CB 3.24Å; V317-M321 WeakPolarHBondContact O-CG 3.35Å; V317-M321 PolarHBondContact O-N 3.3Å
318I94.8Very high91.7Very high0 Ų037.4 Ų37.40%020%0.198CC..Hα-helixtrans-62.6-47.1176.1-67.1162.4000111.2M279 W283 R314 L315 W316 L320 M321 C322 L384 T388 T468M279-I318 HydrophobicContact CE-CG2 4.22Å; M279-I318 HydrophobicContact CG-CG1 4.14Å; W283-I318 HydrophobicContact CH2-CD1 3.45Å; W283-I318 VanDerWaalsContact CH2-CD1 3.45Å; W283-I318 HydrophobicContact CH2-CG1 4.49Å; W283-I318 HydrophobicContact CZ3-CD1 3.98Å; R314-I318 WeakPolarHBondContact O-CG1 3.42Å; R314-I318 PolarHBondContact O-N 2.98Å; R314-I318 VanDerWaalsContact O-N 3.1Å; L315-I318 PolarHBondContact O-N 2.98Å; W316-I318 VanDerWaalsContact C-N 3.31Å; W316-I318 PolarHBondContact O-N 3.31Å; I318-L320 VanDerWaalsContact C-N 3.35Å; I318-L320 PolarHBondContact O-N 3.24Å; I318-M321 PolarHBondContact O-N 3.41Å; I318-C322 WeakPolarHBondContact O-CB 3.17Å; I318-C322 PolarHBondContact O-N 3.08Å; I318-C322 PolarHBondContact O-SG 3.46Å; I318-L384 HydrophobicContact CG2-CD2 4.22Å; I318-L384 HydrophobicContact CG2-CG 4.08Å; I318-T388 HydrophobicContact CB-CG2 4.17Å; I318-T388 HydrophobicContact CD1-CG2 4.08Å; I318-T388 HydrophobicContact CG2-CG2 4.08Å; I318-T388 VanDerWaalsContact CG2-OG1 3.3Å; I318-T388 WeakPolarHBondContact CG2-OG1 3.48Å; I318-T468 HydrophobicContact CD1-CG2 3.56Å
319I94.8Very high92.2Very high34 Ų3433.8 Ų33.817%0.17418%0.181CC..Hα-helixtrans-58.7-47.8177.7-70.3179000110.8L315 W316 M321 C322 V323 L385 W399L315-I319 WeakPolarHBondContact O-CG1 3.13Å; L315-I319 PolarHBondContact O-N 3.27Å; W316-I319 PolarHBondContact O-N 3.15Å; I319-M321 VanDerWaalsContact C-N 3.3Å; I319-M321 PolarHBondContact O-N 3.38Å; I319-C322 WeakPolarHBondContact O-CB 3.44Å; I319-C322 PolarHBondContact O-N 2.97Å; I319-C322 VanDerWaalsContact O-N 3.11Å; I319-V323 HydrophobicContact CG2-CG2 4.4Å; I319-V323 WeakPolarHBondContact O-CG2 3.3Å; I319-V323 PolarHBondContact O-N 3.31Å; I319-L385 HydrophobicContact CG1-CD1 4.33Å; I319-W399 HydrophobicContact CD1-CE3 4.42Å; I319-W399 HydrophobicContact CD1-CH2 3.35Å; I319-W399 HydrophobicContact CD1-CZ2 4.35Å; I319-W399 HydrophobicContact CD1-CZ3 3.37Å; I319-W399 HydrophobicContact CG1-CH2 4.48Å; I319-W399 HydrophobicContact CG1-CZ3 4.49Å
320L95.4Very high92.6Very high111 Ų11136.1 Ų36.158%0.58119%0.188SC*.Hα-helixtrans-58.6-44.2-179.9178.862.8000111.5W316 V317 I318 C322 V323 L324W316-L320 WeakPolarHBondContact O-CB 3.2Å; W316-L320 PolarHBondContact O-N 3.5Å; V317-L320 PolarHBondContact O-N 3.1Å; I318-L320 VanDerWaalsContact C-N 3.35Å; I318-L320 PolarHBondContact O-N 3.24Å; L320-C322 VanDerWaalsContact C-N 3.34Å; L320-V323 PolarHBondContact O-N 2.89Å; L320-L324 WeakPolarHBondContact O-CB 3.5Å; L320-L324 PolarHBondContact O-N 3.22Å
321M94.3Very high92.9Very high21 Ų2139.8 Ų39.810%0.10321%0.205CC..Hα-helixtrans-68.3-34.1177.5-68.3-63.217300112.3I271 I278 M279 V317 I318 I319 L324 R325I271-M321 HydrophobicContact CG2-SD 4.43Å; I278-M321 HydrophobicContact CD1-CE 3.72Å; I278-M321 HydrophobicContact CG2-CE 4.21Å; M279-M321 HydrophobicContact CE-CB 3.26Å; M279-M321 HydrophobicContact CE-CG 4.05Å; V317-M321 HydrophobicContact CG1-CE 4.42Å; V317-M321 HydrophobicContact CG1-CG 4.3Å; V317-M321 WeakPolarHBondContact O-CB 3.24Å; V317-M321 WeakPolarHBondContact O-CG 3.35Å; V317-M321 PolarHBondContact O-N 3.3Å; I318-M321 PolarHBondContact O-N 3.41Å; I319-M321 VanDerWaalsContact C-N 3.3Å; I319-M321 PolarHBondContact O-N 3.38Å; M321-L324 PolarHBondContact O-N 3.41Å; M321-L324 HydrophobicContact SD-CD2 4.23Å; M321-R325 WeakPolarHBondContact O-CB 3.39Å; M321-R325 PolarHBondContact O-N 2.84Å
322C95.1Very high93.2Very high4 Ų439 Ų393%0.02720%0.2CC..Hα-helixtrans-63.8-43.2172.2-74.50000111.8I318 I319 L320 R325 L326 L381I318-C322 WeakPolarHBondContact O-CB 3.17Å; I318-C322 PolarHBondContact O-N 3.08Å; I318-C322 PolarHBondContact O-SG 3.46Å; I319-C322 WeakPolarHBondContact O-CB 3.44Å; I319-C322 PolarHBondContact O-N 2.97Å; I319-C322 VanDerWaalsContact O-N 3.11Å; L320-C322 VanDerWaalsContact C-N 3.34Å; C322-R325 PolarHBondContact O-N 2.86Å; C322-L326 PolarHBondContact O-N 2.67Å; C322-L381 VanDerWaalsContact CA-CD1 3.43Å; C322-L381 HydrophobicContact CB-CD1 3.53Å; C322-L381 VanDerWaalsContact SG-CD1 3.53Å
323V95Very high93.4Very high84 Ų8438.8 Ų38.851%0.50920%0.199SC..Hα-helixtrans-64.4-44.6175.8171.80000111I319 L320 R325 L326 A327I319-V323 HydrophobicContact CG2-CG2 4.4Å; I319-V323 WeakPolarHBondContact O-CG2 3.3Å; I319-V323 PolarHBondContact O-N 3.31Å; L320-V323 PolarHBondContact O-N 2.89Å; V323-R325 PolarHBondContact O-N 3.29Å; V323-L326 PolarHBondContact O-N 3.48Å; V323-A327 WeakPolarHBondContact O-CB 3.42Å; V323-A327 PolarHBondContact O-N 2.95Å
324L94.8Very high93.5Very high31 Ų3137.3 Ų37.316%0.16219%0.19CC..Hα-helixtrans-55.8-43.3174.5175.862.4000111L268 I271 N272 L320 M321 A327 M328L268-L324 HydrophobicContact CB-CD1 4.4Å; L268-L324 HydrophobicContact CD2-CD1 3.86Å; L268-L324 HydrophobicContact CG-CD1 4.29Å; I271-L324 HydrophobicContact CB-CD2 4.18Å; I271-L324 HydrophobicContact CG2-CD2 3.57Å; N272-L324 HydrophobicContact CB-CD2 4.36Å; N272-L324 HydrophobicContact CB-CG 4.36Å; L320-L324 WeakPolarHBondContact O-CB 3.5Å; L320-L324 PolarHBondContact O-N 3.22Å; M321-L324 PolarHBondContact O-N 3.41Å; M321-L324 HydrophobicContact SD-CD2 4.23Å; L324-A327 WeakPolarHBondContact O-CB 3.39Å; L324-A327 PolarHBondContact O-N 3.49Å; L324-M328 HydrophobicContact CD1-CE 4.34Å; L324-M328 HydrophobicContact CD1-CG 4.15Å; L324-M328 WeakPolarHBondContact O-CG 3.33Å; L324-M328 PolarHBondContact O-N 3.48Å
325R94.1Very high93.5Very high7 Ų736.9 Ų36.93%0.02619%0.189CC..Hα-helixtrans-66.8-41.8179.4-161.4157.9-177.9-152.30.8112.7N272 M321 C322 V323 A327 M328 M329 Y377 L381N272-R325 WeakPolarHBondContact OD1-CA 3.44Å; N272-R325 VanDerWaalsContact OD1-CB 3.29Å; N272-R325 WeakPolarHBondContact OD1-CB 3.33Å; N272-R325 VanDerWaalsContact OD1-CG 3.26Å; N272-R325 WeakPolarHBondContact OD1-CG 3.46Å; M321-R325 WeakPolarHBondContact O-CB 3.39Å; M321-R325 PolarHBondContact O-N 2.84Å; C322-R325 PolarHBondContact O-N 2.86Å; V323-R325 PolarHBondContact O-N 3.29Å; R325-A327 VanDerWaalsContact C-N 3.34Å; R325-A327 PolarHBondContact O-N 3.25Å; R325-M328 PolarHBondContact O-N 2.91Å; R325-M329 PolarHBondContact O-N 3.46Å; R325-Y377 HydrophobicContact CG-CE1 3.84Å; R325-Y377 WeakPolarHBondContact CG-OH 3.39Å; R325-Y377 WeakPolarHBondContact O-CE1 3.47Å; R325-Y377 PolarHBondContact O-OH 3.07Å; R325-L381 HydrophobicContact CB-CD1 4.1Å; R325-L381 HydrophobicContact CB-CD2 4.19Å; R325-L381 HydrophobicContact CG-CD1 4.47Å; R325-L381 HydrophobicContact CG-CD2 4.27Å
326L92.8Very high93.5Very high72 Ų7237.3 Ų37.338%0.37719%0.19SC..Hα-helixtrans-59.6-43.6170.4-75.7177.3000112C322 V323 M328 M329 L381C322-L326 PolarHBondContact O-N 2.67Å; V323-L326 PolarHBondContact O-N 3.48Å; L326-M328 VanDerWaalsContact C-N 3.31Å; L326-M328 PolarHBondContact O-N 3.23Å; L326-M329 WeakPolarHBondContact O-CB 3.3Å; L326-M329 PolarHBondContact O-N 2.87Å; L326-L381 HydrophobicContact CB-CD2 4.5Å; L326-L381 HydrophobicContact CD2-CD2 3.44Å; L326-L381 VanDerWaalsContact CD2-CD2 3.44Å; L326-L381 HydrophobicContact CG-CD2 3.55Å
327A92.3Very high93.4Very high59 Ų5931.2 Ų31.249%0.48817%0.168SC..Hα-helixtrans-63.4-37179.100000112.3V323 L324 R325 M329V323-A327 WeakPolarHBondContact O-CB 3.42Å; V323-A327 PolarHBondContact O-N 2.95Å; L324-A327 WeakPolarHBondContact O-CB 3.39Å; L324-A327 PolarHBondContact O-N 3.49Å; R325-A327 VanDerWaalsContact C-N 3.34Å; R325-A327 PolarHBondContact O-N 3.25Å; A327-M329 VanDerWaalsContact C-N 3.35Å
328M93.2Very high93.3Very high15 Ų1531 Ų317%0.07417%0.165CC..Hα-helixtrans-81.6-9.1177.9-64.9-58114.200113.9L268 L269 N272 L324 R325 L326 R330 H331 H332L268-M328 HydrophobicContact CB-CE 4.02Å; L268-M328 HydrophobicContact CB-SD 3.86Å; L268-M328 HydrophobicContact CD2-CE 3.53Å; L268-M328 HydrophobicContact CD2-SD 4.48Å; L268-M328 HydrophobicContact CG-CE 4.42Å; L269-M328 HydrophobicContact CD2-CB 4.43Å; L269-M328 HydrophobicContact CD2-SD 4.23Å; N272-M328 HydrophobicContact CB-CB 4.47Å; N272-M328 HydrophobicContact CB-CG 4.1Å; L324-M328 HydrophobicContact CD1-CE 4.34Å; L324-M328 HydrophobicContact CD1-CG 4.15Å; L324-M328 WeakPolarHBondContact O-CG 3.33Å; L324-M328 PolarHBondContact O-N 3.48Å; R325-M328 PolarHBondContact O-N 2.91Å; L326-M328 VanDerWaalsContact C-N 3.31Å; L326-M328 PolarHBondContact O-N 3.23Å; M328-R330 VanDerWaalsContact C-N 3.31Å; M328-R330 PolarHBondContact O-N 3.37Å; M328-H331 PolarHBondContact O-N 3.46Å; M328-H332 PolarHBondContact O-N 2.97Å; M328-H332 PolarHBondContact O-ND1 3.01Å
329M92.4Very high93.1Very high0 Ų033.2 Ų33.20%018%0.177CC..Hα-helixtrans-54.8-44.3-176.1-180173.2166.200112.9L31 F103 R325 L326 A327 H331 H332 L333 A374 Y377 V378L31-M329 HydrophobicContact CD2-CE 3.61Å; L31-M329 HydrophobicContact CD2-SD 3.59Å; L31-M329 VanDerWaalsContact CD2-SD 3.59Å; L31-M329 HydrophobicContact CG-CE 4.23Å; L31-M329 HydrophobicContact CG-SD 4.27Å; F103-M329 HydrophobicContact CE2-CE 4.11Å; F103-M329 HydrophobicContact CZ-CE 4.15Å; R325-M329 PolarHBondContact O-N 3.46Å; L326-M329 WeakPolarHBondContact O-CB 3.3Å; L326-M329 PolarHBondContact O-N 2.87Å; A327-M329 VanDerWaalsContact C-N 3.35Å; M329-H331 VanDerWaalsContact C-N 3.31Å; M329-H331 PolarHBondContact O-N 3.29Å; M329-H332 PolarHBondContact O-N 3.2Å; M329-H332 VanDerWaalsContact O-N 3.17Å; M329-L333 HydrophobicContact CE-CD1 3.61Å; M329-L333 HydrophobicContact CE-CG 4.44Å; M329-L333 HydrophobicContact CG-CD1 4.07Å; M329-L333 HydrophobicContact CG-CG 4.22Å; M329-L333 WeakPolarHBondContact O-CG 3.45Å; M329-L333 PolarHBondContact O-N 3.07Å; M329-A374 HydrophobicContact CE-CB 3.95Å; M329-Y377 HydrophobicContact CB-CD1 3.99Å; M329-Y377 HydrophobicContact CB-CE1 3.59Å; M329-Y377 HydrophobicContact CG-CD1 3.68Å; M329-Y377 HydrophobicContact CG-CE1 3.83Å; M329-Y377 HydrophobicContact CG-CG 4.36Å; M329-Y377 HydrophobicContact SD-CD1 4.03Å; M329-Y377 HydrophobicContact SD-CE1 4.48Å; M329-V378 HydrophobicContact CE-CG2 3.46Å; M329-V378 VanDerWaalsContact CE-CG2 3.46Å; M329-V378 HydrophobicContact SD-CG2 3.44Å; M329-V378 WeakPolarHBondContact SD-CG2 3.45Å
330R91.4Very high92.8Very high60 Ų6031.9 Ų31.923%0.22617%0.171CC..Hα-helixtrans-62.1-38.1-177.6-64.2179.4-178.1-161.23.7112.4W30 S34 S36 M328 L333 Q334W30-R330 VanDerWaalsContact CZ2-NH2 3.31Å; S34-R330 PolarHBondContact OG-NH1 2.8Å; S34-R330 PolarHBondContact OG-NH2 3.32Å; S34-R330 VanDerWaalsContact OG-NH2 3.1Å; S36-R330 PolarHBondContact OG-NH1 2.88Å; M328-R330 VanDerWaalsContact C-N 3.31Å; M328-R330 PolarHBondContact O-N 3.37Å; R330-L333 PolarHBondContact O-N 2.93Å; R330-Q334 WeakPolarHBondContact O-CB 3.43Å; R330-Q334 PolarHBondContact O-N 3.32Å
331H92Very high92.5Very high79 Ų7928.4 Ų28.437%0.36615%0.151SC..Hα-helixtrans-64.9-41.6176.8-64.790.8000111.4L269 M328 M329 Q334 A335L269-H331 HydrophobicContact CD2-CB 4.41Å; M328-H331 PolarHBondContact O-N 3.46Å; M329-H331 VanDerWaalsContact C-N 3.31Å; M329-H331 PolarHBondContact O-N 3.29Å; H331-Q334 PolarHBondContact O-N 3.47Å; H331-A335 WeakPolarHBondContact O-CB 3.35Å; H331-A335 PolarHBondContact O-N 3.49Å
332H93.4Very high92.2Very high0 Ų030.5 Ų30.50%016%0.16CC..Hα-helixtrans-67.7-41.9176.5-65.892.3000112.1M252 L269 N272 M328 M329 A335 Y336 Y377M252-H332 HydrophobicContact CB-CB 4.18Å; M252-H332 HydrophobicContact SD-CB 4.35Å; L269-H332 VanDerWaalsContact CD2-CE1 3.44Å; L269-H332 WeakPolarHBondContact CD2-CE1 3.42Å; N272-H332 PolarHBondContact ND2-CE1 3.44Å; M328-H332 PolarHBondContact O-N 2.97Å; M328-H332 PolarHBondContact O-ND1 3.01Å; M329-H332 PolarHBondContact O-N 3.2Å; M329-H332 VanDerWaalsContact O-N 3.17Å; H332-A335 WeakPolarHBondContact O-CB 3.3Å; H332-A335 PolarHBondContact O-N 3.43Å; H332-Y336 PolarHBondContact O-N 3.37Å; H332-Y377 HydrophobicContact CB-CD2 4.38Å; H332-Y377 HydrophobicContact CB-CE2 3.91Å; H332-Y377 AromaticContact CG-CE2 3.73Å; H332-Y377 AromaticContact ND1-CE2 3.78Å; H332-Y377 AromaticContact ND1-CZ 3.9Å; H332-Y377 PolarHBondContact ND1-OH 3.5Å
333L92.9Very high91.7Very high0 Ų031.4 Ų31.40%017%0.17CC..Hα-helixtrans-65.6-39.3176.1-71.2-176000112.3L32 L37 M329 R330 A335 Y336 L337 L370 I373 A374L32-L333 HydrophobicContact CD2-CD1 3.98Å; L37-L333 HydrophobicContact CD1-CB 4.43Å; L37-L333 HydrophobicContact CD1-CD1 4.24Å; L37-L333 HydrophobicContact CD2-CB 3.96Å; M329-L333 HydrophobicContact CE-CD1 3.61Å; M329-L333 HydrophobicContact CE-CG 4.44Å; M329-L333 HydrophobicContact CG-CD1 4.07Å; M329-L333 HydrophobicContact CG-CG 4.22Å; M329-L333 WeakPolarHBondContact O-CG 3.45Å; M329-L333 PolarHBondContact O-N 3.07Å; R330-L333 PolarHBondContact O-N 2.93Å; L333-A335 VanDerWaalsContact C-N 3.32Å; L333-A335 PolarHBondContact O-N 2.93Å; L333-Y336 WeakPolarHBondContact O-CB 3.42Å; L333-Y336 PolarHBondContact O-N 3.29Å; L333-L337 WeakPolarHBondContact O-CG 3.23Å; L333-L337 PolarHBondContact O-N 3.28Å; L333-L370 HydrophobicContact CD2-CD1 4.1Å; L333-I373 HydrophobicContact CD2-CG2 4.13Å; L333-A374 HydrophobicContact CD1-CB 4.25Å; L333-A374 HydrophobicContact CD2-CB 4.12Å
334Q93.3Very high91.3Very high37 Ų3727.4 Ų27.417%0.17315%0.146CC..Hα-helixtrans-63.8-40.9174.2-172.659.745.500111.4L37 R38 R330 H331 Y336 L337 N338L37-Q334 HydrophobicContact CD2-CB 4.06Å; R38-Q334 PolarHBondContact O-NE2 3.3Å; R330-Q334 WeakPolarHBondContact O-CB 3.43Å; R330-Q334 PolarHBondContact O-N 3.32Å; H331-Q334 PolarHBondContact O-N 3.47Å; Q334-Y336 PolarHBondContact O-N 3.44Å; Q334-L337 PolarHBondContact O-N 3.02Å; Q334-N338 PolarHBondContact NE2-OD1 2.84Å; Q334-N338 VanDerWaalsContact O-CG 3.23Å; Q334-N338 PolarHBondContact O-N 3.35Å; Q334-N338 PolarHBondContact O-OD1 2.85Å
335A91.7Very high91Very high1 Ų129 Ų291%0.00816%0.155CC..Hα-helixtrans-60.2-37.6175.500000112.3D255 A256 L259 H331 H332 L333 N338D255-A335 HydrophobicContact CB-CB 3.88Å; A256-A335 HydrophobicContact CB-CB 3.78Å; L259-A335 HydrophobicContact CD1-CB 3.85Å; H331-A335 WeakPolarHBondContact O-CB 3.35Å; H331-A335 PolarHBondContact O-N 3.49Å; H332-A335 WeakPolarHBondContact O-CB 3.3Å; H332-A335 PolarHBondContact O-N 3.43Å; L333-A335 VanDerWaalsContact C-N 3.32Å; L333-A335 PolarHBondContact O-N 2.93Å; A335-N338 PolarHBondContact O-N 2.89Å
336Y92.6Very high90.6Very high11 Ų1133.3 Ų33.34%0.04318%0.175CC..Hα-helixtrans-65.5-45.9172.2175.9-104.4000112.9H332 L333 Q334 N338 L339 V366 L370 I373H332-Y336 PolarHBondContact O-N 3.37Å; L333-Y336 WeakPolarHBondContact O-CB 3.42Å; L333-Y336 PolarHBondContact O-N 3.29Å; Q334-Y336 PolarHBondContact O-N 3.44Å; Y336-N338 PolarHBondContact O-N 3.46Å; Y336-L339 HydrophobicContact CE2-CD2 4.26Å; Y336-L339 WeakPolarHBondContact O-CB 3.29Å; Y336-L339 PolarHBondContact O-N 3.4Å; Y336-V366 HydrophobicContact CD1-CG1 4.4Å; Y336-V366 HydrophobicContact CE1-CG1 3.96Å; Y336-V366 WeakPolarHBondContact CE1-O 3.43Å; Y336-V366 WeakPolarHBondContact O-CG1 3.43Å; Y336-L370 HydrophobicContact CD1-CD1 4.14Å; Y336-I373 HydrophobicContact CD1-CB 4.29Å; Y336-I373 HydrophobicContact CD1-CG1 4.02Å; Y336-I373 HydrophobicContact CD1-CG2 4.26Å; Y336-I373 HydrophobicContact CD2-CG1 4.09Å; Y336-I373 HydrophobicContact CD2-CG2 4.33Å; Y336-I373 HydrophobicContact CE1-CB 4.29Å; Y336-I373 HydrophobicContact CE1-CG1 3.62Å; Y336-I373 HydrophobicContact CE2-CD1 4.07Å; Y336-I373 HydrophobicContact CE2-CG1 3.71Å; Y336-I373 HydrophobicContact CG-CG1 4.24Å; Y336-I373 HydrophobicContact CG-CG2 4.07Å; Y336-I373 VanDerWaalsContact CZ-CG1 3.46Å
337L92.1Very high90.2Very high3 Ų330.2 Ų30.22%0.01616%0.159CC..Hα-helixtrans-60.6-33.5177.7-71.1171.8000112.2L37 R38 W39 Y40 I89 L333 Q334 L339 A340 F367 L370L37-L337 HydrophobicContact CB-CD1 4.21Å; L37-L337 HydrophobicContact CD2-CD1 4.34Å; R38-L337 WeakPolarHBondContact O-CD1 3.3Å; W39-L337 HydrophobicContact CB-CD1 4.44Å; W39-L337 HydrophobicContact CB-CD2 4.04Å; Y40-L337 WeakPolarHBondContact CD2-O 3.36Å; I89-L337 HydrophobicContact CD1-CD1 4.16Å; L333-L337 WeakPolarHBondContact O-CG 3.23Å; L333-L337 PolarHBondContact O-N 3.28Å; Q334-L337 PolarHBondContact O-N 3.02Å; L337-L339 PolarHBondContact O-N 3.41Å; L337-A340 PolarHBondContact O-N 3.34Å; L337-F367 HydrophobicContact CD2-CD2 4.36Å; L337-L370 HydrophobicContact CD1-CD1 4.39Å; L337-L370 HydrophobicContact CD2-CD1 3.96Å; L337-L370 HydrophobicContact CD2-CD2 4.26Å; L337-L370 HydrophobicContact CG-CD1 4.08Å
338N91.9Very high89.9Confident21 Ų2130 Ų3011%0.11215%0.147CC..THydrogen-bonded Turntrans-68.7-7.7175.1-66.6-0.7000114Y40 L259 Q334 A335 Y336 A340 Q341 K342Y40-N338 HydrophobicContact CE2-CB 4.5Å; Y40-N338 WeakPolarHBondContact CE2-OD1 3.47Å; L259-N338 HydrophobicContact CD1-CB 4Å; L259-N338 WeakPolarHBondContact CD1-ND2 3.41Å; Q334-N338 PolarHBondContact NE2-OD1 2.84Å; Q334-N338 VanDerWaalsContact O-CG 3.23Å; Q334-N338 PolarHBondContact O-N 3.35Å; Q334-N338 PolarHBondContact O-OD1 2.85Å; A335-N338 PolarHBondContact O-N 2.89Å; Y336-N338 PolarHBondContact O-N 3.46Å; N338-A340 PolarHBondContact O-N 3.36Å; N338-Q341 PolarHBondContact O-N 2.92Å; N338-K342 PolarHBondContact O-N 3.28Å; N338-K342 VanDerWaalsContact O-N 3.15Å
339L89.3Confident89.5Confident48 Ų4836.8 Ų36.825%0.25118%0.176SC..Hα-helixtrans-62.7-29172-167.864.5000112Y336 L337 K342 G343 V366Y336-L339 HydrophobicContact CE2-CD2 4.26Å; Y336-L339 WeakPolarHBondContact O-CB 3.29Å; Y336-L339 PolarHBondContact O-N 3.4Å; L337-L339 PolarHBondContact O-N 3.41Å; L339-K342 PolarHBondContact O-N 3.27Å; L339-G343 PolarHBondContact O-N 2.9Å; L339-V366 HydrophobicContact CB-CG1 4.39Å
340A88.8Confident89.2Confident5 Ų541 Ų414%0.04120%0.196CC..Hα-helixtrans-60.9-46.3175.100000111.8Y40 L84 L337 N338 G343 V344 I363 V366Y40-A340 HydrophobicContact CD2-CB 4.02Å; Y40-A340 HydrophobicContact CG-CB 4.3Å; L84-A340 HydrophobicContact CD1-CB 4.44Å; L337-A340 PolarHBondContact O-N 3.34Å; N338-A340 PolarHBondContact O-N 3.36Å; A340-G343 PolarHBondContact O-N 2.85Å; A340-V344 PolarHBondContact O-N 3.16Å; A340-V344 VanDerWaalsContact O-N 3.16Å; A340-I363 HydrophobicContact CB-CG2 4.31Å; A340-V366 HydrophobicContact CB-CB 4.24Å; A340-V366 HydrophobicContact CB-CG1 4.37Å; A340-V366 HydrophobicContact CB-CG2 4.18Å
341Q89.2Confident88.5Confident38 Ų3843.2 Ų43.218%0.17823%0.227CC..Hα-helixtrans-65.4-45.2176.7-175.161.144.700111.4Y40 N338 G343 V344 D345Y40-Q341 HydrophobicContact CE1-CB 4.03Å; Y40-Q341 HydrophobicContact CE1-CG 4.47Å; Y40-Q341 HydrophobicContact CE2-CB 4.12Å; N338-Q341 PolarHBondContact O-N 2.92Å; Q341-G343 VanDerWaalsContact C-N 3.25Å; Q341-G343 PolarHBondContact O-N 3.27Å; Q341-V344 PolarHBondContact O-N 3.5Å; Q341-V344 VanDerWaalsContact O-N 3.1Å; Q341-D345 PolarHBondContact NE2-OD1 3.32Å; Q341-D345 VanDerWaalsContact O-CG 3.27Å; Q341-D345 PolarHBondContact O-N 3.5Å
342K87.1Confident88.1Confident65 Ų6541.5 Ų41.528%0.28323%0.23SC..Hα-helixtrans-57.4-39.1175.2-72.9177.2175.4167.50112.3D255 N338 L339 D345 Q346D255-K342 IonicContact OD1-NZ 2.7Å; D255-K342 PolarHBondContact OD1-NZ 3Å; D255-K342 IonicContact OD2-NZ 2.88Å; N338-K342 PolarHBondContact O-N 3.28Å; N338-K342 VanDerWaalsContact O-N 3.15Å; L339-K342 PolarHBondContact O-N 3.27Å; K342-D345 PolarHBondContact O-N 2.9Å; K342-Q346 WeakPolarHBondContact O-CB 3.37Å; K342-Q346 PolarHBondContact O-N 2.95Å
343G85.6Confident87.6Confident23 Ų2348.3 Ų48.324%0.23726%0.256CS..Hα-helixtrans-62.3-42.5175.900000112.4L339 A340 Q341 Q346 M347L339-G343 PolarHBondContact O-N 2.9Å; A340-G343 PolarHBondContact O-N 2.85Å; Q341-G343 VanDerWaalsContact C-N 3.25Å; Q341-G343 PolarHBondContact O-N 3.27Å; G343-Q346 PolarHBondContact O-N 2.87Å; G343-M347 WeakPolarHBondContact O-CB 3.4Å; G343-M347 PolarHBondContact O-N 3Å
344V87.2Confident87.2Confident0 Ų049.6 Ų49.60%026%0.262CS..Hα-helixtrans-66-43.1174.1172.40000111.5L82 L84 A340 Q341 Q346 M347 K348 L359 M362 I363L82-V344 HydrophobicContact CB-CG1 4.22Å; L82-V344 HydrophobicContact CD2-CG1 4.16Å; L82-V344 HydrophobicContact CD2-CG2 4.29Å; L84-V344 HydrophobicContact CD1-CB 4.49Å; L84-V344 HydrophobicContact CD1-CG2 3.82Å; L84-V344 HydrophobicContact CD2-CG2 4.34Å; L84-V344 HydrophobicContact CG-CG2 4.25Å; A340-V344 PolarHBondContact O-N 3.16Å; A340-V344 VanDerWaalsContact O-N 3.16Å; Q341-V344 PolarHBondContact O-N 3.5Å; Q341-V344 VanDerWaalsContact O-N 3.1Å; V344-Q346 VanDerWaalsContact C-N 3.3Å; V344-Q346 PolarHBondContact O-N 3.29Å; V344-M347 HydrophobicContact CG1-CE 4.27Å; V344-M347 WeakPolarHBondContact O-CB 3.25Å; V344-M347 PolarHBondContact O-N 2.88Å; V344-K348 WeakPolarHBondContact O-CG 3.41Å; V344-K348 PolarHBondContact O-N 3.01Å; V344-L359 HydrophobicContact CG2-CD1 4.37Å; V344-M362 HydrophobicContact CG2-CE 4.35Å; V344-I363 HydrophobicContact CG2-CD1 4Å; V344-I363 HydrophobicContact CG2-CG1 4.13Å
345D86.9Confident86.8Confident65 Ų6548.3 Ų48.335%0.34826%0.258SS..Hα-helixtrans-65.5-34.3179.2-63.3-24.9000112.2Q341 K342Q341-D345 PolarHBondContact NE2-OD1 3.32Å; Q341-D345 VanDerWaalsContact O-CG 3.27Å; Q341-D345 PolarHBondContact O-N 3.5Å; K342-D345 PolarHBondContact O-N 2.9Å
346Q85.9Confident86.5Confident97 Ų9748.3 Ų48.345%0.45326%0.257SS..Hα-helixtrans-71.3-42.7173.9-171.963.813.700111.3K342 G343 V344 K348 K349K342-Q346 WeakPolarHBondContact O-CB 3.37Å; K342-Q346 PolarHBondContact O-N 2.95Å; G343-Q346 PolarHBondContact O-N 2.87Å; V344-Q346 VanDerWaalsContact C-N 3.3Å; V344-Q346 PolarHBondContact O-N 3.29Å; Q346-K348 VanDerWaalsContact C-N 3.26Å; Q346-K348 PolarHBondContact O-N 2.85Å; Q346-K349 WeakPolarHBondContact O-CB 3.43Å; Q346-K349 PolarHBondContact O-N 3.4Å
347M85.1Confident86.1Confident7 Ų749.9 Ų49.93%0.03427%0.268CS..Hα-helixtrans-56.5-40.7173.9178.3-168.769.100111.4K78 I80 G343 V344 K349 E350 I354 L359 M362K78-M347 HydrophobicContact CB-CG 3.85Å; K78-M347 HydrophobicContact CD-CG 4.12Å; K78-M347 HydrophobicContact CG-CG 3.78Å; K78-M347 HydrophobicContact CG-SD 4.4Å; I80-M347 HydrophobicContact CG2-CE 4.45Å; G343-M347 WeakPolarHBondContact O-CB 3.4Å; G343-M347 PolarHBondContact O-N 3Å; V344-M347 HydrophobicContact CG1-CE 4.27Å; V344-M347 WeakPolarHBondContact O-CB 3.25Å; V344-M347 PolarHBondContact O-N 2.88Å; M347-K349 PolarHBondContact O-N 3.48Å; M347-K349 VanDerWaalsContact O-N 3.13Å; M347-E350 PolarHBondContact O-N 3.34Å; M347-I354 HydrophobicContact SD-CB 4.5Å; M347-I354 HydrophobicContact SD-CD1 3.92Å; M347-I354 HydrophobicContact SD-CG2 3.84Å; M347-L359 HydrophobicContact CE-CD1 3.87Å; M347-L359 HydrophobicContact CE-CD2 4.42Å; M347-L359 HydrophobicContact SD-CD1 3.76Å; M347-M362 HydrophobicContact SD-CE 4.45Å
348K85.4Confident85.9Confident55 Ų5553.8 Ų53.824%0.23929%0.289CS..THydrogen-bonded Turntrans-57.4-25.8176.8-75.3-179.6-177.4-176.10113.6K78 I80 D81 L82 V344 Q346K78-K348 WeakPolarHBondContact O-CA 3.46Å; I80-K348 WeakPolarHBondContact O-CE 3.44Å; D81-K348 IonicContact OD1-NZ 2.79Å; D81-K348 PolarHBondContact OD1-NZ 3.37Å; L82-K348 PolarHBondContact O-NZ 3.38Å; V344-K348 WeakPolarHBondContact O-CG 3.41Å; V344-K348 PolarHBondContact O-N 3.01Å; Q346-K348 VanDerWaalsContact C-N 3.26Å; Q346-K348 PolarHBondContact O-N 2.85Å
349K85.6Confident85.5Confident157 Ų15752.8 Ų52.868%0.68328%0.284SS*.THydrogen-bonded Turntrans-84-19.1178.9-60.3173.2-169.5167.30112.9Q346 M347Q346-K349 WeakPolarHBondContact O-CB 3.43Å; Q346-K349 PolarHBondContact O-N 3.4Å; M347-K349 PolarHBondContact O-N 3.48Å; M347-K349 VanDerWaalsContact O-N 3.13Å
350E85.2Confident85.4Confident89 Ų8952.1 Ų52.142%0.41628%0.279SS..SBendtrans-89.3129.4-178.9-67.1177.9-170.400111.1K78 M347K78-E350 VanDerWaalsContact CB-O 3.3Å; K78-E350 WeakPolarHBondContact CB-O 3.26Å; K78-E350 HydrophobicContact CD-CB 3.96Å; K78-E350 IonicContact NZ-OE2 2.88Å; K78-E350 PolarHBondContact NZ-OE2 2.99Å; M347-E350 PolarHBondContact O-N 3.34Å
351A76.9Confident85.4Confident106 Ų10657.5 Ų57.588%0.87630%0.302SS*.  trans-71.2132.9171.200000110.4
352G84.1Confident85.3Confident43 Ų4358.8 Ų58.844%0.44331%0.309SS..SBendtrans150.5-174172.800000113.9K78K78-G352 PolarHBondContact N-O 3.41Å
353R82.6Confident85.4Confident144 Ų14455.7 Ų55.754%0.54330%0.295SS..EExtended strand (participates in β ladder)trans-115.1140.5171.1-57.3-174.772.176.22.1108.6T75 V76T75-R353 PolarHBondContact O-NH2 2.92Å; T75-R353 PolarHBondContact OG1-NE 3.18Å; T75-R353 VanDerWaalsContact OG1-NE 3.13Å; V76-R353 WeakPolarHBondContact O-CA 3.18Å
354I84.2Confident85.5Confident26 Ų2655.4 Ų55.413%0.13329%0.291CS..EExtended strand (participates in β ladder)trans-114.1148.9172.7-166.8166.6000108.8T75 V76 K78 M347 D358 L359T75-I354 CarbonylContact C-O 3.59Å; T75-I354 VanDerWaalsContact CA-O 3.25Å; T75-I354 WeakPolarHBondContact CA-O 3.07Å; V76-I354 PolarHBondContact N-O 2.89Å; V76-I354 PolarHBondContact O-N 3.31Å; K78-I354 HydrophobicContact CG-CB 4.11Å; K78-I354 HydrophobicContact CG-CG2 4.29Å; M347-I354 HydrophobicContact SD-CB 4.5Å; M347-I354 HydrophobicContact SD-CD1 3.92Å; M347-I354 HydrophobicContact SD-CG2 3.84Å; I354-D358 HydrophobicContact CG1-CB 4.18Å; I354-L359 HydrophobicContact CD1-CB 4.23Å; I354-L359 HydrophobicContact CG2-CB 4.27Å
355S85.9Confident85.6Confident11 Ų1163.9 Ų63.98%0.07732%0.323CS..EExtended strand (participates in β ladder)trans-72143169.488.30000109.6V357 D358 L359S355-V357 PolarHBondContact O-N 2.95Å; S355-D358 WeakPolarHBondContact CB-OD2 3.21Å; S355-D358 PolarHBondContact O-N 2.67Å; S355-D358 VanDerWaalsContact OG-CB 3.28Å; S355-D358 WeakPolarHBondContact OG-CB 3.46Å; S355-D358 PolarHBondContact OG-N 2.9Å; S355-D358 PolarHBondContact OG-OD2 2.74Å; S355-L359 PolarHBondContact O-N 3.34Å
356T84.5Confident85.8Confident0 Ų061.5 Ų61.50%031%0.31CS..Hα-helixtrans-55.5-40.9174.742.70000111.4L48 L74 V76 L359 Q360L48-T356 HydrophobicContact CB-CG2 4.29Å; L48-T356 HydrophobicContact CD1-CG2 3.72Å; L74-T356 HydrophobicContact CB-CG2 4.03Å; L74-T356 HydrophobicContact CD2-CG2 4.02Å; L74-T356 HydrophobicContact CG-CG2 4.22Å; L74-T356 WeakPolarHBondContact O-CB 3.45Å; L74-T356 WeakPolarHBondContact O-CG2 3.48Å; L74-T356 PolarHBondContact O-N 3.45Å; L74-T356 PolarHBondContact O-OG1 3.31Å; V76-T356 HydrophobicContact CG2-CG2 3.54Å; T356-L359 PolarHBondContact O-N 2.99Å; T356-Q360 WeakPolarHBondContact O-CB 3.4Å; T356-Q360 VanDerWaalsContact O-CG 3.3Å; T356-Q360 WeakPolarHBondContact O-CG 3.42Å; T356-Q360 PolarHBondContact O-N 3.23Å
357V85.8Confident86Confident45 Ų4557.3 Ų57.327%0.27329%0.291SS..Hα-helixtrans-62.3-43.6177179.60000111.6P73 S355 Q360 K361P73-V357 HydrophobicContact CB-CG2 4Å; S355-V357 PolarHBondContact O-N 2.95Å; V357-Q360 PolarHBondContact O-N 3.26Å; V357-K361 HydrophobicContact CG1-CD 4.04Å; V357-K361 HydrophobicContact CG1-CG 4.46Å; V357-K361 VanDerWaalsContact O-CB 3.3Å; V357-K361 WeakPolarHBondContact O-CB 3.41Å; V357-K361 WeakPolarHBondContact O-CG 3.33Å; V357-K361 PolarHBondContact O-N 3.46Å
358D86.1Confident86.2Confident84 Ų8462.5 Ų62.545%0.44931%0.311SS..Hα-helixtrans-71.1-36.9-179.9-62.3-35.1000111.6I354 S355 K361 M362I354-D358 HydrophobicContact CG1-CB 4.18Å; S355-D358 WeakPolarHBondContact CB-OD2 3.21Å; S355-D358 PolarHBondContact O-N 2.67Å; S355-D358 VanDerWaalsContact OG-CB 3.28Å; S355-D358 WeakPolarHBondContact OG-CB 3.46Å; S355-D358 PolarHBondContact OG-N 2.9Å; S355-D358 PolarHBondContact OG-OD2 2.74Å; D358-K361 PolarHBondContact O-N 3.01Å; D358-M362 WeakPolarHBondContact O-CB 3.45Å; D358-M362 PolarHBondContact O-N 3.35Å
359L85.4Confident86.4Confident0 Ų061.9 Ų61.90%031%0.307CS..Hα-helixtrans-62.1-48.7172.7175.356.5000111.5L48 L82 V344 M347 I354 S355 T356 K361 M362 I363L48-L359 HydrophobicContact CD1-CD2 4.23Å; L48-L359 HydrophobicContact CD2-CD2 3.81Å; L82-L359 HydrophobicContact CD2-CD2 4.26Å; V344-L359 HydrophobicContact CG2-CD1 4.37Å; M347-L359 HydrophobicContact CE-CD1 3.87Å; M347-L359 HydrophobicContact CE-CD2 4.42Å; M347-L359 HydrophobicContact SD-CD1 3.76Å; I354-L359 HydrophobicContact CD1-CB 4.23Å; I354-L359 HydrophobicContact CG2-CB 4.27Å; S355-L359 PolarHBondContact O-N 3.34Å; T356-L359 PolarHBondContact O-N 2.99Å; L359-K361 PolarHBondContact O-N 3.08Å; L359-M362 HydrophobicContact CD1-CE 3.44Å; L359-M362 VanDerWaalsContact CD1-CE 3.44Å; L359-M362 PolarHBondContact O-N 2.85Å; L359-I363 HydrophobicContact CD1-CD1 3.82Å; L359-I363 HydrophobicContact CD1-CG1 4.48Å; L359-I363 HydrophobicContact CG-CD1 4.17Å; L359-I363 WeakPolarHBondContact O-CG1 3.31Å; L359-I363 PolarHBondContact O-N 3.1Å; L359-I363 VanDerWaalsContact O-N 3.15Å
360Q87.1Confident86.8Confident34 Ų3454.4 Ų54.416%0.15928%0.275CS..Hα-helixtrans-61.5-44.1176.1-74.5173.9-12.400111.4H42 P43 T356 V357 M362 I363 A364H42-Q360 HydrophobicContact CB-CB 4.39Å; H42-Q360 HydrophobicContact CB-CG 4.36Å; P43-Q360 PolarHBondContact O-NE2 2.87Å; T356-Q360 WeakPolarHBondContact O-CB 3.4Å; T356-Q360 VanDerWaalsContact O-CG 3.3Å; T356-Q360 WeakPolarHBondContact O-CG 3.42Å; T356-Q360 PolarHBondContact O-N 3.23Å; V357-Q360 PolarHBondContact O-N 3.26Å; Q360-M362 PolarHBondContact O-N 2.91Å; Q360-I363 PolarHBondContact O-N 3.29Å; Q360-A364 WeakPolarHBondContact O-CB 3.3Å; Q360-A364 PolarHBondContact O-N 3.45Å
361K88.2Confident87.1Confident119 Ų11950.1 Ų50.152%0.51726%0.255SS..Hα-helixtrans-60.9-42.3176-79.2173.8-178.9173.20112.1V357 D358 L359 R365V357-K361 HydrophobicContact CG1-CD 4.04Å; V357-K361 HydrophobicContact CG1-CG 4.46Å; V357-K361 VanDerWaalsContact O-CB 3.3Å; V357-K361 WeakPolarHBondContact O-CB 3.41Å; V357-K361 WeakPolarHBondContact O-CG 3.33Å; V357-K361 PolarHBondContact O-N 3.46Å; D358-K361 PolarHBondContact O-N 3.01Å; L359-K361 PolarHBondContact O-N 3.08Å; K361-R365 WeakPolarHBondContact O-CB 3.37Å; K361-R365 PolarHBondContact O-N 3.42Å
362M87.7Confident87.9Confident64 Ų6445.1 Ų45.132%0.31521%0.213SC..Hα-helixtrans-58.9-47.8177.6176.8-175.459.800111.2V344 M347 D358 L359 Q360V344-M362 HydrophobicContact CG2-CE 4.35Å; M347-M362 HydrophobicContact SD-CE 4.45Å; D358-M362 WeakPolarHBondContact O-CB 3.45Å; D358-M362 PolarHBondContact O-N 3.35Å; L359-M362 HydrophobicContact CD1-CE 3.44Å; L359-M362 VanDerWaalsContact CD1-CE 3.44Å; L359-M362 PolarHBondContact O-N 2.85Å; Q360-M362 PolarHBondContact O-N 2.91Å
363I88.4Confident88.3Confident1 Ų143.1 Ų43.11%0.00519%0.192CC..Hα-helixtrans-69.4-49.2-180-64.8159000110.7H42 P43 L82 L84 A340 V344 L359 Q360 R365 V366H42-I363 HydrophobicContact CB-CG2 4.33Å; P43-I363 HydrophobicContact CG-CD1 4.38Å; L82-I363 HydrophobicContact CD2-CD1 4.48Å; L84-I363 HydrophobicContact CD1-CD1 4.43Å; L84-I363 HydrophobicContact CD1-CG1 4.41Å; L84-I363 HydrophobicContact CD1-CG2 4.5Å; L84-I363 HydrophobicContact CD2-CD1 3.62Å; L84-I363 HydrophobicContact CD2-CG1 4.42Å; A340-I363 HydrophobicContact CB-CG2 4.31Å; V344-I363 HydrophobicContact CG2-CD1 4Å; V344-I363 HydrophobicContact CG2-CG1 4.13Å; L359-I363 HydrophobicContact CD1-CD1 3.82Å; L359-I363 HydrophobicContact CD1-CG1 4.48Å; L359-I363 HydrophobicContact CG-CD1 4.17Å; L359-I363 WeakPolarHBondContact O-CG1 3.31Å; L359-I363 PolarHBondContact O-N 3.1Å; L359-I363 VanDerWaalsContact O-N 3.15Å; Q360-I363 PolarHBondContact O-N 3.29Å; I363-R365 VanDerWaalsContact C-N 3.32Å; I363-R365 PolarHBondContact O-N 3.35Å; I363-V366 PolarHBondContact O-N 3.29Å
364A88Confident88.9Confident17 Ų1736.2 Ų36.214%0.1417%0.166CC..Hα-helixtrans-63.4-36.8-176.900000112.4Q360 V366 F367 Y368Q360-A364 WeakPolarHBondContact O-CB 3.3Å; Q360-A364 PolarHBondContact O-N 3.45Å; A364-V366 VanDerWaalsContact C-N 3.25Å; A364-V366 PolarHBondContact O-N 3.31Å; A364-F367 PolarHBondContact O-N 3.35Å; A364-Y368 HydrophobicContact CB-CD2 4.06Å; A364-Y368 HydrophobicContact CB-CE2 4.02Å; A364-Y368 WeakPolarHBondContact O-CD2 3.43Å; A364-Y368 PolarHBondContact O-N 2.93Å
365R89.4Confident89.4Confident177 Ų17735 Ų3567%0.66816%0.16SC*.Hα-helixtrans-56.4-39.3179-175.7-173.2-60.3179.40.2112.1K361 I363 F367 Y368 Y369K361-R365 WeakPolarHBondContact O-CB 3.37Å; K361-R365 PolarHBondContact O-N 3.42Å; I363-R365 VanDerWaalsContact C-N 3.32Å; I363-R365 PolarHBondContact O-N 3.35Å; R365-F367 VanDerWaalsContact C-N 3.3Å; R365-F367 PolarHBondContact O-N 3.4Å; R365-Y368 PolarHBondContact O-N 3.05Å; R365-Y369 WeakPolarHBondContact O-CB 3.18Å; R365-Y369 PolarHBondContact O-N 3.42Å
366V90.5Very high89.8Confident15 Ų1534.7 Ų34.79%0.09116%0.157CC..Hα-helixtrans-60-43.5178.2179.80000110.5Y336 L339 A340 I363 A364Y336-V366 HydrophobicContact CD1-CG1 4.4Å; Y336-V366 HydrophobicContact CE1-CG1 3.96Å; Y336-V366 WeakPolarHBondContact CE1-O 3.43Å; Y336-V366 WeakPolarHBondContact O-CG1 3.43Å; L339-V366 HydrophobicContact CB-CG1 4.39Å; A340-V366 HydrophobicContact CB-CB 4.24Å; A340-V366 HydrophobicContact CB-CG1 4.37Å; A340-V366 HydrophobicContact CB-CG2 4.18Å; I363-V366 PolarHBondContact O-N 3.29Å; A364-V366 VanDerWaalsContact C-N 3.25Å; A364-V366 PolarHBondContact O-N 3.31Å
367F89.6Confident90.2Very high10 Ų1034.8 Ų34.84%0.04416%0.158CC..Hα-helixtrans-69.7-51.9177.9-178.8-114.8000112W39 I89 D93 L97 L337 A364 R365 Y369 L370W39-F367 HydrophobicContact CB-CD2 3.53Å; W39-F367 HydrophobicContact CB-CE2 3.96Å; W39-F367 HydrophobicContact CB-CG 4.35Å; W39-F367 AromaticContact CD1-CE2 3.87Å; W39-F367 HydrophobicContact CD2-CB 4.46Å; W39-F367 HydrophobicContact CD2-CD1 4.2Å; W39-F367 AromaticContact CD2-CD2 3.67Å; W39-F367 HydrophobicContact CD2-CD2 3.67Å; W39-F367 HydrophobicContact CD2-CE1 4.4Å; W39-F367 AromaticContact CD2-CE2 3.9Å; W39-F367 HydrophobicContact CD2-CE2 3.9Å; W39-F367 AromaticContact CD2-CG 3.84Å; W39-F367 HydrophobicContact CD2-CG 3.84Å; W39-F367 HydrophobicContact CD2-CZ 4.26Å; W39-F367 HydrophobicContact CE3-CB 3.76Å; W39-F367 AromaticContact CE3-CD1 3.91Å; W39-F367 HydrophobicContact CE3-CD1 3.91Å; W39-F367 AromaticContact CE3-CD2 3.85Å; W39-F367 HydrophobicContact CE3-CD2 3.85Å; W39-F367 HydrophobicContact CE3-CE2 4.45Å; W39-F367 AromaticContact CE3-CG 3.54Å; W39-F367 HydrophobicContact CE3-CG 3.54Å; W39-F367 AromaticContact CG-CD2 3.55Å; W39-F367 HydrophobicContact CG-CD2 3.55Å; W39-F367 AromaticContact CG-CE2 3.65Å; W39-F367 HydrophobicContact CG-CE2 3.65Å; W39-F367 HydrophobicContact CG-CG 4.21Å; W39-F367 HydrophobicContact CG-CZ 4.37Å; W39-F367 HydrophobicContact CH2-CD1 4.41Å; W39-F367 HydrophobicContact CZ2-CE1 4.5Å; W39-F367 HydrophobicContact CZ3-CB 4.27Å; W39-F367 HydrophobicContact CZ3-CD1 4.02Å; W39-F367 HydrophobicContact CZ3-CG 4.08Å; I89-F367 HydrophobicContact CD1-CE2 4.28Å; I89-F367 HydrophobicContact CG1-CE2 4.17Å; D93-F367 HydrophobicContact CB-CE1 4.24Å; D93-F367 HydrophobicContact CB-CZ 3.84Å; L97-F367 HydrophobicContact CD2-CD1 4.02Å; L97-F367 HydrophobicContact CD2-CD2 4.32Å; L97-F367 HydrophobicContact CD2-CE1 3.76Å; L97-F367 HydrophobicContact CD2-CE2 4.07Å; L97-F367 HydrophobicContact CD2-CG 4.3Å; L97-F367 HydrophobicContact CD2-CZ 3.78Å; L97-F367 WeakPolarHBondContact CD2-O 3.38Å; L97-F367 HydrophobicContact CG-CZ 4.33Å; L337-F367 HydrophobicContact CD2-CD2 4.36Å; A364-F367 PolarHBondContact O-N 3.35Å; R365-F367 VanDerWaalsContact C-N 3.3Å; R365-F367 PolarHBondContact O-N 3.4Å; F367-Y369 PolarHBondContact O-N 3.11Å; F367-Y369 VanDerWaalsContact O-N 3.11Å; F367-L370 HydrophobicContact CE2-CD2 4.44Å; F367-L370 WeakPolarHBondContact O-CB 3.31Å; F367-L370 PolarHBondContact O-N 2.93Å
368Y89.8Confident90.7Very high115 Ų11532.9 Ų32.945%0.45115%0.146SC..Hα-helixtrans-60.3-26.6-177.6-77.1-68.9000114A96 Y98 A364 R365A96-Y368 HydrophobicContact CB-CE1 3.96Å; A96-Y368 VanDerWaalsContact O-CD1 3.24Å; A96-Y368 WeakPolarHBondContact O-CD1 3.15Å; A96-Y368 WeakPolarHBondContact O-CE1 3.47Å; Y98-Y368 WeakPolarHBondContact CB-O 3.46Å; Y98-Y368 PolarHBondContact N-O 3.05Å; Y98-Y368 VanDerWaalsContact N-O 3.17Å; A364-Y368 HydrophobicContact CB-CD2 4.06Å; A364-Y368 HydrophobicContact CB-CE2 4.02Å; A364-Y368 WeakPolarHBondContact O-CD2 3.43Å; A364-Y368 PolarHBondContact O-N 2.93Å; R365-Y368 PolarHBondContact O-N 3.05Å
369Y90.4Very high91.2Very high42 Ų4228.9 Ų28.917%0.16513%0.125CC..THydrogen-bonded Turntrans-89.4-0.7179.1-153.9-106.5000113.7Y158 R365 F367 C371 V372 I373Y158-Y369 VanDerWaalsContact CZ-OH 3.3Å; Y158-Y369 PolarHBondContact OH-OH 2.94Å; R365-Y369 WeakPolarHBondContact O-CB 3.18Å; R365-Y369 PolarHBondContact O-N 3.42Å; F367-Y369 PolarHBondContact O-N 3.11Å; F367-Y369 VanDerWaalsContact O-N 3.11Å; Y369-C371 VanDerWaalsContact C-N 3.33Å; Y369-C371 PolarHBondContact O-N 2.83Å; Y369-V372 HydrophobicContact CD1-CB 4.03Å; Y369-V372 HydrophobicContact CD1-CG1 4.29Å; Y369-V372 HydrophobicContact CD2-CB 4.13Å; Y369-V372 HydrophobicContact CD2-CG2 3.99Å; Y369-V372 HydrophobicContact CE1-CB 3.83Å; Y369-V372 HydrophobicContact CE1-CG1 3.57Å; Y369-V372 HydrophobicContact CE2-CB 3.94Å; Y369-V372 HydrophobicContact CE2-CG1 3.94Å; Y369-V372 HydrophobicContact CE2-CG2 3.83Å; Y369-V372 HydrophobicContact CG-CB 4.18Å; Y369-V372 HydrophobicContact CG-CG2 4.46Å; Y369-V372 WeakPolarHBondContact O-CB 3.46Å; Y369-V372 PolarHBondContact O-N 3.14Å; Y369-V372 VanDerWaalsContact O-N 3.11Å; Y369-V372 WeakPolarHBondContact OH-CG1 3.38Å; Y369-I373 HydrophobicContact CD1-CD1 3.7Å; Y369-I373 HydrophobicContact CD1-CG1 3.84Å; Y369-I373 HydrophobicContact CE1-CD1 3.7Å; Y369-I373 HydrophobicContact CE1-CG1 4.31Å; Y369-I373 PolarHBondContact O-N 2.88Å
370L92.3Very high91.6Very high0 Ų028.9 Ų28.90%013%0.125CC..Hα-helixtrans-53.5-44.9-177.317764.6000113.3L32 I89 L97 L333 Y336 L337 F367 V372 I373 A374L32-L370 HydrophobicContact CD2-CD2 4.41Å; I89-L370 HydrophobicContact CD1-CD2 3.53Å; L97-L370 HydrophobicContact CD1-CD2 4.43Å; L97-L370 HydrophobicContact CD2-CB 4.39Å; L333-L370 HydrophobicContact CD2-CD1 4.1Å; Y336-L370 HydrophobicContact CD1-CD1 4.14Å; L337-L370 HydrophobicContact CD1-CD1 4.39Å; L337-L370 HydrophobicContact CD2-CD1 3.96Å; L337-L370 HydrophobicContact CD2-CD2 4.26Å; L337-L370 HydrophobicContact CG-CD1 4.08Å; F367-L370 HydrophobicContact CE2-CD2 4.44Å; F367-L370 WeakPolarHBondContact O-CB 3.31Å; F367-L370 PolarHBondContact O-N 2.93Å; L370-V372 VanDerWaalsContact C-N 3.32Å; L370-V372 PolarHBondContact O-N 3.16Å; L370-I373 PolarHBondContact O-N 3.41Å; L370-A374 WeakPolarHBondContact O-CB 3.5Å; L370-A374 PolarHBondContact O-N 3.31Å
371C92.5Very high92Very high0 Ų027.6 Ų27.60%012%0.119CC..Hα-helixtrans-66.6-33.4-178.9-79.30000112.7L97 Y98 F103 Y369 I373 A374 L375L97-C371 HydrophobicContact CB-CB 4.45Å; L97-C371 VanDerWaalsContact CD1-SG 3.57Å; Y98-C371 WeakPolarHBondContact O-CB 3.21Å; F103-C371 HydrophobicContact CB-CB 4.41Å; Y369-C371 VanDerWaalsContact C-N 3.33Å; Y369-C371 PolarHBondContact O-N 2.83Å; C371-I373 VanDerWaalsContact C-N 3.33Å; C371-A374 PolarHBondContact O-N 2.98Å; C371-L375 WeakPolarHBondContact O-CB 3.13Å; C371-L375 WeakPolarHBondContact O-CG 3.46Å; C371-L375 PolarHBondContact O-N 3.16Å
372V92.9Very high92.5Very high0 Ų022.3 Ų22.30%010%0.096CC..Hα-helixtrans-63.4-43.5173.4176.40000110.4Y98 Y99 L154 Y369 L370 L375 Q376Y98-V372 HydrophobicContact CD1-CG2 3.9Å; Y98-V372 HydrophobicContact CE1-CG2 4.45Å; Y99-V372 HydrophobicContact CD2-CG2 3.68Å; Y99-V372 HydrophobicContact CE2-CG2 4.45Å; Y99-V372 HydrophobicContact CG-CG2 4.22Å; L154-V372 HydrophobicContact CD2-CG1 3.7Å; Y369-V372 HydrophobicContact CD1-CB 4.03Å; Y369-V372 HydrophobicContact CD1-CG1 4.29Å; Y369-V372 HydrophobicContact CD2-CB 4.13Å; Y369-V372 HydrophobicContact CD2-CG2 3.99Å; Y369-V372 HydrophobicContact CE1-CB 3.83Å; Y369-V372 HydrophobicContact CE1-CG1 3.57Å; Y369-V372 HydrophobicContact CE2-CB 3.94Å; Y369-V372 HydrophobicContact CE2-CG1 3.94Å; Y369-V372 HydrophobicContact CE2-CG2 3.83Å; Y369-V372 HydrophobicContact CG-CB 4.18Å; Y369-V372 HydrophobicContact CG-CG2 4.46Å; Y369-V372 WeakPolarHBondContact O-CB 3.46Å; Y369-V372 PolarHBondContact O-N 3.14Å; Y369-V372 VanDerWaalsContact O-N 3.11Å; Y369-V372 WeakPolarHBondContact OH-CG1 3.38Å; L370-V372 VanDerWaalsContact C-N 3.32Å; L370-V372 PolarHBondContact O-N 3.16Å; V372-L375 WeakPolarHBondContact O-CB 3.33Å; V372-L375 PolarHBondContact O-N 3.26Å; V372-Q376 WeakPolarHBondContact O-CG 3.32Å; V372-Q376 PolarHBondContact O-N 2.84Å
373I92.7Very high92.9Very high1 Ų119.7 Ų19.71%0.0058%0.084CC..Hα-helixtrans-65.9-41.3176.7-58.6-54.4000111.6R248 M252 L333 Y336 Y369 L370 C371 L375 Q376 Y377R248-I373 HydrophobicContact CG-CD1 3.95Å; M252-I373 HydrophobicContact CE-CG2 3.49Å; M252-I373 VanDerWaalsContact CE-CG2 3.49Å; M252-I373 HydrophobicContact SD-CG2 3.4Å; M252-I373 WeakPolarHBondContact SD-CG2 3.42Å; L333-I373 HydrophobicContact CD2-CG2 4.13Å; Y336-I373 HydrophobicContact CD1-CB 4.29Å; Y336-I373 HydrophobicContact CD1-CG1 4.02Å; Y336-I373 HydrophobicContact CD1-CG2 4.26Å; Y336-I373 HydrophobicContact CD2-CG1 4.09Å; Y336-I373 HydrophobicContact CD2-CG2 4.33Å; Y336-I373 HydrophobicContact CE1-CB 4.29Å; Y336-I373 HydrophobicContact CE1-CG1 3.62Å; Y336-I373 HydrophobicContact CE2-CD1 4.07Å; Y336-I373 HydrophobicContact CE2-CG1 3.71Å; Y336-I373 HydrophobicContact CG-CG1 4.24Å; Y336-I373 HydrophobicContact CG-CG2 4.07Å; Y336-I373 VanDerWaalsContact CZ-CG1 3.46Å; Y369-I373 HydrophobicContact CD1-CD1 3.7Å; Y369-I373 HydrophobicContact CD1-CG1 3.84Å; Y369-I373 HydrophobicContact CE1-CD1 3.7Å; Y369-I373 HydrophobicContact CE1-CG1 4.31Å; Y369-I373 PolarHBondContact O-N 2.88Å; L370-I373 PolarHBondContact O-N 3.41Å; C371-I373 VanDerWaalsContact C-N 3.33Å; I373-L375 VanDerWaalsContact C-N 3.33Å; I373-L375 PolarHBondContact O-N 3.5Å; I373-Q376 PolarHBondContact O-N 3.41Å; I373-Y377 PolarHBondContact O-N 2.91Å
374A94.8Very high93.2Very high0 Ų019.7 Ų19.70%08%0.084CC..Hα-helixtrans-61.8-41.3175.300000111.6F103 M329 L333 L370 C371 Y377 V378F103-A374 HydrophobicContact CD2-CB 3.83Å; F103-A374 HydrophobicContact CE2-CB 3.48Å; F103-A374 VanDerWaalsContact CE2-CB 3.48Å; F103-A374 HydrophobicContact CZ-CB 4.02Å; M329-A374 HydrophobicContact CE-CB 3.95Å; L333-A374 HydrophobicContact CD1-CB 4.25Å; L333-A374 HydrophobicContact CD2-CB 4.12Å; L370-A374 WeakPolarHBondContact O-CB 3.5Å; L370-A374 PolarHBondContact O-N 3.31Å; C371-A374 PolarHBondContact O-N 2.98Å; A374-Y377 PolarHBondContact O-N 3.5Å; A374-V378 WeakPolarHBondContact O-CB 3.18Å; A374-V378 WeakPolarHBondContact O-CG2 3.3Å; A374-V378 PolarHBondContact O-N 3.5Å
375L94.9Very high93.7Very high0 Ų020.4 Ų20.40%09%0.085CC..Hα-helixtrans-61.7-44.1173-80.1172.6000112.2Y99 E102 F103 L106 I150 L154 C371 V372 I373 Y377 V378 A379Y99-L375 HydrophobicContact CD1-CD1 4.21Å; Y99-L375 HydrophobicContact CG-CD1 4.36Å; E102-L375 HydrophobicContact CB-CD1 4.25Å; F103-L375 HydrophobicContact CB-CD1 4.35Å; F103-L375 HydrophobicContact CB-CD2 4.04Å; F103-L375 HydrophobicContact CB-CG 3.94Å; F103-L375 HydrophobicContact CD2-CD2 4.05Å; F103-L375 HydrophobicContact CD2-CG 4.07Å; L106-L375 HydrophobicContact CB-CD2 4.25Å; L106-L375 HydrophobicContact CD2-CD2 3.61Å; I150-L375 HydrophobicContact CD1-CD2 4.33Å; I150-L375 HydrophobicContact CG2-CD1 4.16Å; I150-L375 HydrophobicContact CG2-CD2 3.97Å; I150-L375 HydrophobicContact CG2-CG 4.46Å; L154-L375 HydrophobicContact CD1-CB 4.1Å; C371-L375 WeakPolarHBondContact O-CB 3.13Å; C371-L375 WeakPolarHBondContact O-CG 3.46Å; C371-L375 PolarHBondContact O-N 3.16Å; V372-L375 WeakPolarHBondContact O-CB 3.33Å; V372-L375 PolarHBondContact O-N 3.26Å; I373-L375 VanDerWaalsContact C-N 3.33Å; I373-L375 PolarHBondContact O-N 3.5Å; L375-Y377 PolarHBondContact O-N 3.07Å; L375-V378 PolarHBondContact O-N 2.77Å; L375-A379 WeakPolarHBondContact O-CB 3.29Å; L375-A379 PolarHBondContact O-N 3.38Å
376Q94.3Very high94Very high4 Ų412 Ų122%0.0195%0.053CC..Hα-helixtrans-62.8-30.8176.9-74.3179.7-9.600112.9L154 Y158 P245 V372 I373 P380L154-Q376 HydrophobicContact CD1-CG 3.95Å; Y158-Q376 VanDerWaalsContact CE2-NE2 3.31Å; Y158-Q376 PolarHBondContact OH-NE2 3.31Å; P245-Q376 HydrophobicContact CB-CB 4.36Å; P245-Q376 WeakPolarHBondContact CB-O 3.47Å; P245-Q376 HydrophobicContact CG-CB 4.3Å; P245-Q376 HydrophobicContact CG-CG 4.25Å; V372-Q376 WeakPolarHBondContact O-CG 3.32Å; V372-Q376 PolarHBondContact O-N 2.84Å; I373-Q376 PolarHBondContact O-N 3.41Å; Q376-P380 WeakPolarHBondContact O-CD 2.89Å; Q376-P380 WeakPolarHBondContact O-CG 3.31Å
377Y94.3Very high94.3Very high3 Ų311.5 Ų11.51%0.0125%0.05CC..Hα-helixtrans-76-45.4174.9-166.6-84.8000112.2L249 M252 R325 M329 H332 I373 A374 L375L249-Y377 HydrophobicContact CD1-CD2 3.72Å; L249-Y377 HydrophobicContact CD1-CE2 3.4Å; M252-Y377 HydrophobicContact CE-CD2 4.44Å; R325-Y377 HydrophobicContact CG-CE1 3.84Å; R325-Y377 WeakPolarHBondContact CG-OH 3.39Å; R325-Y377 WeakPolarHBondContact O-CE1 3.47Å; R325-Y377 PolarHBondContact O-OH 3.07Å; M329-Y377 HydrophobicContact CB-CD1 3.99Å; M329-Y377 HydrophobicContact CB-CE1 3.59Å; M329-Y377 HydrophobicContact CG-CD1 3.68Å; M329-Y377 HydrophobicContact CG-CE1 3.83Å; M329-Y377 HydrophobicContact CG-CG 4.36Å; M329-Y377 HydrophobicContact SD-CD1 4.03Å; M329-Y377 HydrophobicContact SD-CE1 4.48Å; H332-Y377 HydrophobicContact CB-CD2 4.38Å; H332-Y377 HydrophobicContact CB-CE2 3.91Å; H332-Y377 AromaticContact CG-CE2 3.73Å; H332-Y377 AromaticContact ND1-CE2 3.78Å; H332-Y377 AromaticContact ND1-CZ 3.9Å; H332-Y377 PolarHBondContact ND1-OH 3.5Å; I373-Y377 PolarHBondContact O-N 2.91Å; A374-Y377 PolarHBondContact O-N 3.5Å; L375-Y377 PolarHBondContact O-N 3.07Å
378V95.4Very high94.6Very high4 Ų411 Ų112%0.0245%0.048CC..Hα-helixtrans-81.4-39.7-172.2173.50000112.7F103 L106 V107 M329 A374 L375 L381 V382F103-V378 HydrophobicContact CE2-CG2 4.34Å; L106-V378 HydrophobicContact CD2-CG1 4.4Å; V107-V378 HydrophobicContact CG2-CG1 4.09Å; M329-V378 HydrophobicContact CE-CG2 3.46Å; M329-V378 VanDerWaalsContact CE-CG2 3.46Å; M329-V378 HydrophobicContact SD-CG2 3.44Å; M329-V378 WeakPolarHBondContact SD-CG2 3.45Å; A374-V378 WeakPolarHBondContact O-CB 3.18Å; A374-V378 WeakPolarHBondContact O-CG2 3.3Å; A374-V378 PolarHBondContact O-N 3.5Å; L375-V378 PolarHBondContact O-N 2.77Å; V378-L381 VanDerWaalsContact O-CB 3.32Å; V378-L381 WeakPolarHBondContact O-CB 3.4Å; V378-L381 PolarHBondContact O-N 2.83Å; V378-L381 VanDerWaalsContact O-N 3.08Å; V378-V382 HydrophobicContact CG1-CG2 3.57Å; V378-V382 WeakPolarHBondContact O-CG2 3.49Å; V378-V382 PolarHBondContact O-N 3.14Å
379A95.9Very high94.8Very high0 Ų05.9 Ų5.90%03%0.029CC..Hα-helixtrans-57.2-48.1-173.800000113.5L106 V147 L151 L375 L381 V382 M383L106-A379 HydrophobicContact CD2-CB 4.09Å; V147-A379 HydrophobicContact CG1-CB 4.13Å; V147-A379 WeakPolarHBondContact CG1-O 3.42Å; L151-A379 HydrophobicContact CD2-CB 3.9Å; L151-A379 HydrophobicContact CG-CB 4.17Å; L375-A379 WeakPolarHBondContact O-CB 3.29Å; L375-A379 PolarHBondContact O-N 3.38Å; A379-L381 VanDerWaalsContact C-N 3.25Å; A379-L381 PolarHBondContact O-N 3.01Å; A379-V382 PolarHBondContact O-N 3.15Å; A379-M383 WeakPolarHBondContact O-CB 3.28Å; A379-M383 PolarHBondContact O-N 2.95Å
380P95.5Very high95Very high1 Ų14 Ų41%0.0062%0.021CC..Hα-helixtrans-64.8-31.3177.4-19.632.3000113.5L242 P245 Q376 L384 L475L242-P380 HydrophobicContact CD2-CB 3.63Å; L242-P380 HydrophobicContact CD2-CG 3.6Å; P245-P380 HydrophobicContact CB-CG 3.87Å; P245-P380 HydrophobicContact CG-CG 4.4Å; Q376-P380 WeakPolarHBondContact O-CD 2.89Å; Q376-P380 WeakPolarHBondContact O-CG 3.31Å; P380-L384 WeakPolarHBondContact O-CB 3.44Å; P380-L384 PolarHBondContact O-N 3.16Å; P380-L475 HydrophobicContact CB-CD1 4.03Å; P380-L475 HydrophobicContact CB-CD2 3.7Å; P380-L475 HydrophobicContact CB-CG 4.32Å; P380-L475 HydrophobicContact CG-CD2 4.16Å
381L95.4Very high95Very high6 Ų64.1 Ų4.13%0.0312%0.022CC..Hα-helixtrans-70.3-44.7178.6174.261.9000111.4C322 R325 L326 V378 A379 M383 L384 L385C322-L381 VanDerWaalsContact CA-CD1 3.43Å; C322-L381 HydrophobicContact CB-CD1 3.53Å; C322-L381 VanDerWaalsContact SG-CD1 3.53Å; R325-L381 HydrophobicContact CB-CD1 4.1Å; R325-L381 HydrophobicContact CB-CD2 4.19Å; R325-L381 HydrophobicContact CG-CD1 4.47Å; R325-L381 HydrophobicContact CG-CD2 4.27Å; L326-L381 HydrophobicContact CB-CD2 4.5Å; L326-L381 HydrophobicContact CD2-CD2 3.44Å; L326-L381 VanDerWaalsContact CD2-CD2 3.44Å; L326-L381 HydrophobicContact CG-CD2 3.55Å; V378-L381 VanDerWaalsContact O-CB 3.32Å; V378-L381 WeakPolarHBondContact O-CB 3.4Å; V378-L381 PolarHBondContact O-N 2.83Å; V378-L381 VanDerWaalsContact O-N 3.08Å; A379-L381 VanDerWaalsContact C-N 3.25Å; A379-L381 PolarHBondContact O-N 3.01Å; L381-M383 VanDerWaalsContact C-N 3.33Å; L381-L384 PolarHBondContact O-N 3.05Å; L381-L385 WeakPolarHBondContact O-CB 3.23Å; L381-L385 PolarHBondContact O-N 3.41Å
382V96.9Very high95.1Very high8 Ų85.4 Ų5.45%0.0483%0.027CC..Hα-helixtrans-61.8-43.4173.2173.20000110.8L106 T110 V143 V147 V378 A379 L384 L385 H386L106-V382 HydrophobicContact CD1-CG1 4.42Å; T110-V382 HydrophobicContact CG2-CB 4.38Å; T110-V382 HydrophobicContact CG2-CG1 3.75Å; T110-V382 HydrophobicContact CG2-CG2 3.8Å; T110-V382 WeakPolarHBondContact OG1-CG1 3.4Å; V143-V382 HydrophobicContact CG1-CG1 3.27Å; V147-V382 HydrophobicContact CG2-CB 3.94Å; V147-V382 HydrophobicContact CG2-CG1 3.55Å; V378-V382 HydrophobicContact CG1-CG2 3.57Å; V378-V382 WeakPolarHBondContact O-CG2 3.49Å; V378-V382 PolarHBondContact O-N 3.14Å; A379-V382 PolarHBondContact O-N 3.15Å; V382-L384 VanDerWaalsContact C-N 3.34Å; V382-L384 PolarHBondContact O-N 2.72Å; V382-L385 PolarHBondContact O-N 3.36Å; V382-H386 PolarHBondContact O-N 3.27Å; V382-H386 PolarHBondContact O-ND1 2.86Å; V382-H386 VanDerWaalsContact O-ND1 3.11Å
383M96.3Very high94.9Very high9 Ų96.9 Ų6.94%0.0444%0.037CC..Hα-helixtrans-57.1-49.3176.2-157168.44900111.2L144 V147 L151 I238 L242 A379 L381 T387 I471L144-M383 HydrophobicContact CD2-CB 4.46Å; L144-M383 HydrophobicContact CD2-CG 3.89Å; V147-M383 HydrophobicContact CG1-CB 3.93Å; V147-M383 HydrophobicContact CG1-CG 4.17Å; V147-M383 HydrophobicContact CG1-SD 4.15Å; L151-M383 HydrophobicContact CD1-CE 4.48Å; L151-M383 HydrophobicContact CD1-SD 4.33Å; I238-M383 HydrophobicContact CG2-CE 4.25Å; L242-M383 HydrophobicContact CD1-CE 3.81Å; L242-M383 HydrophobicContact CD2-CE 3.8Å; L242-M383 HydrophobicContact CG-CE 4.11Å; A379-M383 WeakPolarHBondContact O-CB 3.28Å; A379-M383 PolarHBondContact O-N 2.95Å; L381-M383 VanDerWaalsContact C-N 3.33Å; M383-T387 VanDerWaalsContact O-CB 3.28Å; M383-T387 WeakPolarHBondContact O-CB 3.32Å; M383-T387 PolarHBondContact O-N 3.47Å; M383-T387 PolarHBondContact O-OG1 3.39Å; M383-I471 HydrophobicContact CE-CB 4.4Å; M383-I471 HydrophobicContact CE-CD1 3.91Å; M383-I471 HydrophobicContact CE-CG1 3.77Å; M383-I471 HydrophobicContact CE-CG2 3.77Å; M383-I471 HydrophobicContact CG-CD1 3.84Å; M383-I471 HydrophobicContact SD-CD1 4.22Å
384L96.1Very high94.7Very high1 Ų18.8 Ų8.81%0.0055%0.046CC..Hα-helixtrans-64-46-179.6-17669.5000111.8M279 I318 P380 L381 V382 T387 T388 T468 I471M279-L384 HydrophobicContact CE-CD2 3.57Å; M279-L384 HydrophobicContact SD-CD2 3.45Å; M279-L384 WeakPolarHBondContact SD-CD2 3.05Å; I318-L384 HydrophobicContact CG2-CD2 4.22Å; I318-L384 HydrophobicContact CG2-CG 4.08Å; P380-L384 WeakPolarHBondContact O-CB 3.44Å; P380-L384 PolarHBondContact O-N 3.16Å; L381-L384 PolarHBondContact O-N 3.05Å; V382-L384 VanDerWaalsContact C-N 3.34Å; V382-L384 PolarHBondContact O-N 2.72Å; L384-T387 PolarHBondContact O-N 2.84Å; L384-T388 WeakPolarHBondContact O-CB 3.37Å; L384-T388 PolarHBondContact O-N 3.41Å; L384-T388 PolarHBondContact O-OG1 3.44Å; L384-T468 HydrophobicContact CD1-CG2 3.83Å; L384-I471 HydrophobicContact CB-CG2 4.25Å; L384-I471 HydrophobicContact CD1-CB 4.36Å; L384-I471 HydrophobicContact CD1-CG2 4.16Å
385L96.9Very high94.1Very high32 Ų329.2 Ų9.217%0.1685%0.051CC..Hα-helixtrans-57.5-53177.6178.864.7000111.1I319 L381 V382 T387 T388 L389I319-L385 HydrophobicContact CG1-CD1 4.33Å; L381-L385 WeakPolarHBondContact O-CB 3.23Å; L381-L385 PolarHBondContact O-N 3.41Å; V382-L385 PolarHBondContact O-N 3.36Å; L385-T387 PolarHBondContact O-N 3.39Å; L385-T388 WeakPolarHBondContact O-CA 3.32Å; L385-T388 WeakPolarHBondContact O-CB 3.39Å; L385-T388 PolarHBondContact O-N 3.41Å; L385-T388 VanDerWaalsContact O-N 3.1Å; L385-L389 WeakPolarHBondContact O-CG 3.48Å; L385-L389 PolarHBondContact O-N 2.91Å
386H96.8Very high93.4Very high0 Ų012.3 Ų12.30%08%0.083CC..Hα-helixtrans-72.1-31.5-175-73.969.9000112.9T110 T114 V143 L144 V382 T388 L389 L390T110-H386 VanDerWaalsContact CG2-CE1 3.49Å; T110-H386 WeakPolarHBondContact CG2-CE1 3.37Å; T114-H386 PolarHBondContact OG1-CE1 2.79Å; V143-H386 HydrophobicContact CG1-CB 4.42Å; L144-H386 HydrophobicContact CD2-CB 3.87Å; L144-H386 HydrophobicContact CG-CB 4.12Å; V382-H386 PolarHBondContact O-N 3.27Å; V382-H386 PolarHBondContact O-ND1 2.86Å; V382-H386 VanDerWaalsContact O-ND1 3.11Å; H386-T388 VanDerWaalsContact C-N 3.27Å; H386-T388 PolarHBondContact O-N 3.22Å; H386-L389 PolarHBondContact O-N 2.94Å; H386-L390 WeakPolarHBondContact O-CB 3.31Å; H386-L390 VanDerWaalsContact O-CG 3.29Å; H386-L390 WeakPolarHBondContact O-CG 3.39Å; H386-L390 PolarHBondContact O-N 3.18Å
387T96.2Very high92.9Very high6 Ų613.4 Ų13.44%0.0379%0.088CC..Hα-helixtrans-63.4-36.4170.2-52.40000110.7M383 L384 L385 L390 L391 F464 F467 T468 I471M383-T387 VanDerWaalsContact O-CB 3.28Å; M383-T387 WeakPolarHBondContact O-CB 3.32Å; M383-T387 PolarHBondContact O-N 3.47Å; M383-T387 PolarHBondContact O-OG1 3.39Å; L384-T387 PolarHBondContact O-N 2.84Å; L385-T387 PolarHBondContact O-N 3.39Å; T387-L390 PolarHBondContact O-N 3.42Å; T387-L391 WeakPolarHBondContact O-CB 3.36Å; T387-L391 PolarHBondContact O-N 3.21Å; T387-F464 HydrophobicContact CG2-CD1 3.83Å; T387-F467 HydrophobicContact CG2-CB 3.93Å; T387-T468 VanDerWaalsContact CG2-OG1 3.3Å; T387-T468 WeakPolarHBondContact CG2-OG1 3.39Å; T387-I471 HydrophobicContact CG2-CD1 4.42Å
388T95.4Very high92.3Very high0 Ų014.3 Ų14.30%010%0.095CC..Hα-helixtrans-70.1-40.4176.2-52.90000112.1L315 I318 L384 L385 H386 L390 L391 K392L315-T388 HydrophobicContact CB-CG2 4.44Å; L315-T388 HydrophobicContact CD2-CG2 3.62Å; I318-T388 HydrophobicContact CB-CG2 4.17Å; I318-T388 HydrophobicContact CD1-CG2 4.08Å; I318-T388 HydrophobicContact CG2-CG2 4.08Å; I318-T388 VanDerWaalsContact CG2-OG1 3.3Å; I318-T388 WeakPolarHBondContact CG2-OG1 3.48Å; L384-T388 WeakPolarHBondContact O-CB 3.37Å; L384-T388 PolarHBondContact O-N 3.41Å; L384-T388 PolarHBondContact O-OG1 3.44Å; L385-T388 WeakPolarHBondContact O-CA 3.32Å; L385-T388 WeakPolarHBondContact O-CB 3.39Å; L385-T388 PolarHBondContact O-N 3.41Å; L385-T388 VanDerWaalsContact O-N 3.1Å; H386-T388 VanDerWaalsContact C-N 3.27Å; H386-T388 PolarHBondContact O-N 3.22Å; T388-L390 VanDerWaalsContact C-N 3.33Å; T388-L390 PolarHBondContact O-N 3.23Å; T388-L391 WeakPolarHBondContact O-CB 3.35Å; T388-L391 PolarHBondContact O-N 3.5Å; T388-K392 PolarHBondContact O-N 2.99Å
389L95.1Very high91.6Very high7 Ų715.2 Ų15.24%0.03710%0.098CC..Hα-helixtrans-63.6-39.7174.7-61.8-176.6000111.6Y117 L385 H386 K392 T393 W399Y117-L389 HydrophobicContact CD1-CD1 3.94Å; Y117-L389 HydrophobicContact CD1-CD2 4.07Å; Y117-L389 HydrophobicContact CD1-CG 4.41Å; Y117-L389 HydrophobicContact CD2-CB 4.26Å; Y117-L389 HydrophobicContact CD2-CD1 4.36Å; Y117-L389 HydrophobicContact CE1-CB 4.19Å; Y117-L389 HydrophobicContact CE1-CD1 4.25Å; Y117-L389 HydrophobicContact CE1-CD2 3.62Å; Y117-L389 HydrophobicContact CE1-CG 4.21Å; Y117-L389 HydrophobicContact CE2-CB 3.81Å; Y117-L389 HydrophobicContact CG-CD1 4Å; Y117-L389 PolarHBondContact OH-O 2.99Å; Y117-L389 VanDerWaalsContact OH-O 3.09Å; L385-L389 WeakPolarHBondContact O-CG 3.48Å; L385-L389 PolarHBondContact O-N 2.91Å; H386-L389 PolarHBondContact O-N 2.94Å; L389-K392 PolarHBondContact O-N 3.49Å; L389-T393 PolarHBondContact O-N 3.13Å; L389-T393 PolarHBondContact O-OG1 3.3Å; L389-W399 HydrophobicContact CD2-CH2 4.14Å; L389-W399 HydrophobicContact CD2-CZ2 4Å
390L94.5Very high90.6Very high1 Ų122.2 Ų22.21%0.00512%0.124CC..Hα-helixtrans-67-41.6173.7-71.8170.6000112.1V137 C140 L141 L144 H386 T387 T388 K392 T393 L394 F464V137-L390 HydrophobicContact CB-CD2 4.34Å; V137-L390 HydrophobicContact CG1-CD2 3.74Å; C140-L390 HydrophobicContact CB-CD1 4.19Å; C140-L390 HydrophobicContact CB-CD2 3.79Å; C140-L390 HydrophobicContact CB-CG 3.83Å; L141-L390 HydrophobicContact CD2-CD1 3.79Å; L141-L390 HydrophobicContact CG-CD1 4.35Å; L141-L390 HydrophobicContact CG-CD2 4.42Å; L144-L390 HydrophobicContact CD1-CD1 3.46Å; L144-L390 VanDerWaalsContact CD1-CD1 3.46Å; L144-L390 HydrophobicContact CG-CD1 4.47Å; H386-L390 WeakPolarHBondContact O-CB 3.31Å; H386-L390 VanDerWaalsContact O-CG 3.29Å; H386-L390 WeakPolarHBondContact O-CG 3.39Å; H386-L390 PolarHBondContact O-N 3.18Å; T387-L390 PolarHBondContact O-N 3.42Å; T388-L390 VanDerWaalsContact C-N 3.33Å; T388-L390 PolarHBondContact O-N 3.23Å; L390-K392 VanDerWaalsContact C-N 3.27Å; L390-K392 PolarHBondContact O-N 3.05Å; L390-T393 PolarHBondContact O-N 2.96Å; L390-L394 HydrophobicContact CD2-CD1 4.02Å; L390-L394 WeakPolarHBondContact O-CB 3.4Å; L390-L394 PolarHBondContact O-N 2.85Å; L390-F464 HydrophobicContact CB-CD1 3.93Å; L390-F464 HydrophobicContact CB-CD2 4.33Å; L390-F464 HydrophobicContact CB-CE1 3.74Å; L390-F464 HydrophobicContact CB-CE2 4.18Å; L390-F464 HydrophobicContact CB-CG 4.23Å; L390-F464 HydrophobicContact CB-CZ 3.89Å; L390-F464 HydrophobicContact CD1-CD1 4.45Å; L390-F464 HydrophobicContact CD1-CE1 3.61Å; L390-F464 HydrophobicContact CD1-CZ 3.86Å; L390-F464 HydrophobicContact CG-CE1 4.3Å; L390-F464 HydrophobicContact CG-CZ 4.37Å
391L93.4Very high88.9Confident3 Ų325.9 Ų25.92%0.01615%0.146CC..Hα-helixtrans-55.6-45.2173.1177.555000110.8W283 L315 T387 T388 G395 F464W283-L391 HydrophobicContact CZ2-CD2 4.3Å; L315-L391 HydrophobicContact CD2-CD2 3.99Å; L315-L391 HydrophobicContact CD2-CG 4.21Å; T387-L391 WeakPolarHBondContact O-CB 3.36Å; T387-L391 PolarHBondContact O-N 3.21Å; T388-L391 WeakPolarHBondContact O-CB 3.35Å; T388-L391 PolarHBondContact O-N 3.5Å; L391-G395 WeakPolarHBondContact O-CA 3.32Å; L391-G395 PolarHBondContact O-N 3.02Å; L391-F464 HydrophobicContact CB-CB 3.79Å; L391-F464 HydrophobicContact CD1-CB 3.95Å; L391-F464 HydrophobicContact CG-CB 4.42Å
392K93Very high87Confident27 Ų2731.4 Ų31.412%0.11717%0.167CC..Hα-helixtrans-61.4-53.3177.3-175.8-95164.4-1760111.8Y117 E121 L315 T388 L389 L390 G396 H397 W399Y117-K392 WeakPolarHBondContact OH-CD 3.02Å; E121-K392 IonicContact OE1-NZ 3.77Å; E121-K392 PolarHBondContact OE1-NZ 2.87Å; E121-K392 WeakPolarHBondContact OE2-CE 3.02Å; E121-K392 IonicContact OE2-NZ 2.62Å; E121-K392 PolarHBondContact OE2-NZ 3.01Å; L315-K392 HydrophobicContact CD1-CB 3.87Å; L315-K392 HydrophobicContact CD1-CG 3.92Å; T388-K392 PolarHBondContact O-N 2.99Å; L389-K392 PolarHBondContact O-N 3.49Å; L390-K392 VanDerWaalsContact C-N 3.27Å; L390-K392 PolarHBondContact O-N 3.05Å; K392-G396 PolarHBondContact O-N 3.27Å; K392-H397 WeakPolarHBondContact CE-O 3.45Å; K392-H397 HydrophobicContact CG-CB 4.42Å; K392-H397 PolarHBondContact O-N 3.48Å; K392-H397 VanDerWaalsContact O-N 3.15Å; K392-W399 HydrophobicContact CB-CH2 4.31Å; K392-W399 HydrophobicContact CB-CZ2 4Å; K392-W399 HydrophobicContact CD-CZ2 3.93Å; K392-W399 VanDerWaalsContact CE-CD1 3.5Å; K392-W399 HydrophobicContact CG-CD2 4.22Å; K392-W399 HydrophobicContact CG-CH2 4.28Å; K392-W399 HydrophobicContact CG-CZ2 3.72Å
393T90.2Very high84.5Confident32 Ų3235.1 Ų35.120%0.19619%0.192CC..Hα-helixtrans-74.1-43.7-170.2-62.90000113Y117 N134 V137 L389 L390Y117-T393 VanDerWaalsContact CE2-OG1 3.23Å; Y117-T393 WeakPolarHBondContact CE2-OG1 3.23Å; Y117-T393 PolarHBondContact OH-OG1 3.19Å; N134-T393 VanDerWaalsContact ND2-CG2 3.32Å; N134-T393 WeakPolarHBondContact ND2-CG2 3.34Å; V137-T393 HydrophobicContact CG2-CG2 3.65Å; L389-T393 PolarHBondContact O-N 3.13Å; L389-T393 PolarHBondContact O-OG1 3.3Å; L390-T393 PolarHBondContact O-N 2.96Å
394L87.9Confident82Confident40 Ų4043.2 Ų43.221%0.20923%0.23CC..Hα-helixtrans-89.1-25.8-177.3-63.2173.8000112.5V137 L390 G396 P457 F460 F464V137-L394 HydrophobicContact CG1-CD1 4.04Å; V137-L394 HydrophobicContact CG1-CD2 4.22Å; V137-L394 HydrophobicContact CG1-CG 4.39Å; V137-L394 HydrophobicContact CG2-CD2 4.17Å; V137-L394 HydrophobicContact CG2-CG 4.45Å; L390-L394 HydrophobicContact CD2-CD1 4.02Å; L390-L394 WeakPolarHBondContact O-CB 3.4Å; L390-L394 PolarHBondContact O-N 2.85Å; L394-G396 VanDerWaalsContact C-N 3.34Å; L394-P457 VanDerWaalsContact O-CA 3.3Å; L394-P457 WeakPolarHBondContact O-CA 3.24Å; L394-P457 WeakPolarHBondContact O-CB 3.39Å; L394-F460 HydrophobicContact CB-CB 3.71Å; L394-F460 HydrophobicContact CB-CD2 4.23Å; L394-F460 HydrophobicContact CB-CG 4.01Å; L394-F460 HydrophobicContact CD1-CD1 4.29Å; L394-F460 HydrophobicContact CD1-CG 4.32Å; L394-F464 HydrophobicContact CB-CE2 4.44Å; L394-F464 HydrophobicContact CD1-CD2 4.34Å; L394-F464 HydrophobicContact CD1-CE2 3.49Å; L394-F464 VanDerWaalsContact CD1-CE2 3.49Å; L394-F464 HydrophobicContact CD1-CZ 4.06Å
395G81.3Confident79.3Confident9 Ų951.9 Ų51.99%0.09327%0.27CS..Hα-helixtrans-84.6-3.6177.400000114.7L391L391-G395 WeakPolarHBondContact O-CA 3.32Å; L391-G395 PolarHBondContact O-N 3.02Å
396G81.3Confident76.2Confident65 Ų6556.5 Ų56.567%0.6730%0.295SS*.THydrogen-bonded Turntrans75.321.117600000114.8K392 L394K392-G396 PolarHBondContact O-N 3.27Å; L394-G396 VanDerWaalsContact C-N 3.34Å
397H82.4Confident73.2Confident28 Ų2862.2 Ų62.213%0.1333%0.325CS..  trans-79.6149.5175.9-62.4-66000111.2D311 L315 K392 R461D311-H397 IonicContact OD2-CE1 3.72Å; D311-H397 PolarHBondContact OD2-CE1 3.38Å; D311-H397 VanDerWaalsContact OD2-CE1 3.22Å; D311-H397 IonicContact OD2-ND1 3.07Å; L315-H397 HydrophobicContact CD1-CB 3.74Å; K392-H397 WeakPolarHBondContact CE-O 3.45Å; K392-H397 HydrophobicContact CG-CB 4.42Å; K392-H397 PolarHBondContact O-N 3.48Å; K392-H397 VanDerWaalsContact O-N 3.15Å; H397-R461 PolarHBondContact CE1-NE 2.8Å
398S81.8Confident70.2Confident21 Ų2166.9 Ų66.915%0.14736%0.355CS..  trans-98.7154.9170.356.90000110.5Q308 S312 W400Q308-S398 PolarHBondContact NE2-OG 3.26Å; S312-S398 PolarHBondContact OG-O 3.5Å; S312-S398 VanDerWaalsContact OG-O 3.08Å; S398-W400 WeakPolarHBondContact CB-O 3.48Å; S398-W400 PolarHBondContact OG-O 3.04Å
399W81.3Confident67.3Low23 Ų2373.1 Ų73.19%0.08740%0.398CS..SBendtrans-84.9-19.6167.7-52.199.7000112.7Y117 E121 L315 W316 I319 L389 K392Y117-W399 HydrophobicContact CE1-CZ2 4.35Å; E121-W399 VanDerWaalsContact OE2-CD1 3.28Å; E121-W399 PolarHBondContact OE2-NE1 3.21Å; L315-W399 HydrophobicContact CB-CE3 4.31Å; L315-W399 HydrophobicContact CB-CH2 4.31Å; L315-W399 HydrophobicContact CB-CZ3 3.65Å; L315-W399 HydrophobicContact CD1-CZ3 4.38Å; W316-W399 HydrophobicContact CZ2-CB 4.47Å; W316-W399 HydrophobicContact CZ2-CE3 4.39Å; W316-W399 PolarHBondContact NE1-O 3.38Å; I319-W399 HydrophobicContact CD1-CE3 4.42Å; I319-W399 HydrophobicContact CD1-CH2 3.35Å; I319-W399 HydrophobicContact CD1-CZ2 4.35Å; I319-W399 HydrophobicContact CD1-CZ3 3.37Å; I319-W399 HydrophobicContact CG1-CH2 4.48Å; I319-W399 HydrophobicContact CG1-CZ3 4.49Å; L389-W399 HydrophobicContact CD2-CH2 4.14Å; L389-W399 HydrophobicContact CD2-CZ2 4Å; K392-W399 HydrophobicContact CB-CH2 4.31Å; K392-W399 HydrophobicContact CB-CZ2 4Å; K392-W399 HydrophobicContact CD-CZ2 3.93Å; K392-W399 VanDerWaalsContact CE-CD1 3.5Å; K392-W399 HydrophobicContact CG-CD2 4.22Å; K392-W399 HydrophobicContact CG-CH2 4.28Å; K392-W399 HydrophobicContact CG-CZ2 3.72Å
400W75.6Confident64.2Low148 Ų14880.1 Ų80.156%0.56143%0.434SS*.SBendtrans-108.3139.9-179.5-61.1-104.8000109.3S398 Y402S398-W400 WeakPolarHBondContact CB-O 3.48Å; S398-W400 PolarHBondContact OG-O 3.04Å; W400-Y402 HydrophobicContact CB-CE2 4.36Å; W400-Y402 PolarHBondContact O-N 3.46Å
401V59.6Low61.2Low78 Ų7887.2 Ų87.247%0.47347%0.467SS..  trans-81.6101.5166.4-173.90000105.5A309A309-V401 HydrophobicContact CB-CB 4.47Å; A309-V401 HydrophobicContact CB-CG1 4.04Å; A309-V401 HydrophobicContact CB-CG2 3.55Å
402Y55.4Low58Low121 Ų12195.9 Ų95.948%0.47551%0.507SS..  trans-72.9132167.1-66.7-78.2000107.2W400 E404W400-Y402 HydrophobicContact CB-CE2 4.36Å; W400-Y402 PolarHBondContact O-N 3.46Å; Y402-E404 PolarHBondContact O-N 3.44Å
403P43.9Very low55Low86 Ų86101.4 Ų101.456%0.55854%0.537SS*.  trans-54134.7164.6-19.331.1000108.3E405 D406P403-E405 PolarHBondContact O-N 3.44Å; P403-D406 PolarHBondContact O-N 3.05Å
404E43.9Very low52Low179 Ų179107 Ų10784%0.83657%0.566SS**G310 helixtrans-55.9-7.6-178.1-108.7165.8153.200114.2Y402Y402-E404 PolarHBondContact O-N 3.44Å
405E39.1Very low49.3Very low184 Ų184109.9 Ų109.986%0.8659%0.589SS**G310 helixtrans-81.1-14.4-179-61.8-171.9163.300114.4P403P403-E405 PolarHBondContact O-N 3.44Å
406D33.3Very low46.8Very low128 Ų128116.8 Ų116.868%0.68462%0.624SS**G310 helixtrans-112.218.1-175.2-80.2-30.2000115P403 P408P403-D406 PolarHBondContact O-N 3.05Å; D406-P408 WeakPolarHBondContact O-CD 3.34Å
407L33.4Very low44.2Very low120 Ų120119.6 Ų119.663%0.62863%0.633SS**  trans-85.9108.1172.2-129.689.6000110.2C409L407-C409 PolarHBondContact O-N 3.24Å; L407-C409 VanDerWaalsContact O-N 3.12Å
408P33Very low41.7Very low105 Ų105124.9 Ų124.968%0.68267%0.667SS**  trans-64.6117.2162.225.3-29.9000107.5D406 L410D406-P408 WeakPolarHBondContact O-CD 3.34Å; P408-L410 PolarHBondContact O-N 3.22Å
409C34Very low39.2Very low131 Ų131131.8 Ų131.889%0.88570%0.7SS**  trans-50.296.7173.2-58.60000109.8L407 H411L407-C409 PolarHBondContact O-N 3.24Å; L407-C409 VanDerWaalsContact O-N 3.12Å; C409-H411 PolarHBondContact O-N 3.03Å
410L30.8Very low36.5Very low153 Ų153134.3 Ų134.380%0.80173%0.734SS**  trans-93.795.1178.2-124.7173.5000109.4P408P408-L410 PolarHBondContact O-N 3.22Å
411H30Very low34.4Very low151 Ų151133.4 Ų133.470%0.69975%0.745SS**  trans70.389.2149-91.419.1000118.9C409 I413C409-H411 PolarHBondContact O-N 3.03Å; H411-I413 PolarHBondContact O-N 3.35Å
412E27.5Very low32.9Very low184 Ų184138.9 Ų138.986%0.8677%0.765SS**  -51.7119.5124.1-72.7-177.2149.200108.8N414E412-N414 PolarHBondContact O-N 2.76Å; E412-N414 VanDerWaalsContact O-N 3.11Å
413I29.5Very low31.6Very low144 Ų144142.5 Ų142.574%0.73879%0.786SS**  trans-74101.7170.3-66.5170.2000106.3H411 S415H411-I413 PolarHBondContact O-N 3.35Å; I413-S415 PolarHBondContact O-N 2.88Å
414N27.1Very low30.9Very low150 Ų150147.6 Ų147.680%0.80281%0.805SS**  trans-54107.2167.2-110.9-5.8000109E412 D416E412-N414 PolarHBondContact O-N 2.76Å; E412-N414 VanDerWaalsContact O-N 3.11Å; N414-D416 PolarHBondContact O-N 2.91Å
415S30.8Very low30.1Very low100 Ų100143.4 Ų143.470%0.69980%0.801SS**  trans-78.9101.8156-56.70000105.4I413I413-S415 PolarHBondContact O-N 2.88Å
416D28.8Very low29.7Very low154 Ų154140.8 Ų140.882%0.82480%0.8SS**  trans166.1102.6151.8-85.5-17.7000110.4N414N414-D416 PolarHBondContact O-N 2.91Å
417S26.5Very low29.6Very low124 Ų124143.1 Ų143.187%0.86781%0.812SS**  trans173.374.4144.8410000110.3
418V29.8Very low29.3Very low138 Ų138146.8 Ų146.884%0.83682%0.823SS**  trans-108111.7154.91770000106
419I30.7Very low29.6Very low166 Ų166147.1 Ų147.185%0.85182%0.824SS**  trans171.9110.5141.2-81.8149.3000106
420G25.1Very low29.4Very low76 Ų76148.3 Ų148.378%0.78482%0.822SS**  trans-167.176.2179.300000109.2E422G420-E422 PolarHBondContact O-N 2.94Å
421T30.8Very low29.5Very low129 Ų129145.9 Ų145.979%0.79181%0.814SS**  trans-67.1115.9179.4-24.50000110.2
422E27.7Very low30.1Very low193 Ų193145.2 Ų145.290%0.90282%0.82SS**  trans-141.4144.5158.9-76-161.1164.500112.4G420G420-E422 PolarHBondContact O-N 2.94Å
423Q27.7Very low30.8Very low197 Ų197142.9 Ų142.992%0.92182%0.818SS**  trans-82.4153.8-153.4-77.4160.3-39.900114.9
424M29.6Very low31.4Very low193 Ų193141.5 Ų141.595%0.95181%0.808SS**  trans-71.2132.5177.7-161.8165.3-126.900112.3
425A27.1Very low32.6Very low92 Ų92138.6 Ų138.676%0.7680%0.796SS**  trans-129.6138.3158.200000109.3
426P31.7Very low33.5Very low129 Ų129136.2 Ų136.284%0.83879%0.788SS**PPolyproline II helixtrans-88.4134.9-16333.8-32000112.1
427L29.7Very low34.6Very low177 Ų177131.7 Ų131.793%0.92777%0.772SS**PPolyproline II helixtrans-103.4132.1166.9-152.776.5000109.9
428K28.2Very low36Very low197 Ų197133.8 Ų133.886%0.85776%0.76SS**PPolyproline II helixtrans-60.8156.6-179.6-115.6177.4171.8177.50112.7
429P38.5Very low37.4Very low111 Ų111129.4 Ų129.472%0.72174%0.739SS**PPolyproline II helixtrans-91.1128.3-170.434.7-26.4000110.7
430D29.5Very low38.8Very low156 Ų156124.5 Ų124.583%0.83472%0.719SS**  trans-141.4131.5159-87.8-40.1000111
431T33.7Very low40.7Very low103 Ų103125.3 Ų125.363%0.63271%0.709SS**  trans75.594.6169.363.80000118.8V433T431-V433 VanDerWaalsContact C-N 3.27Å; T431-V433 PolarHBondContact O-N 2.69Å
432V41.4Very low42.4Very low137 Ų137121.4 Ų121.483%0.8369%0.689SS**THydrogen-bonded Turntrans-77.43.9-178.6173.30000114.1
433V42.5Very low44.3Very low134 Ų134118.4 Ų118.481%0.81268%0.676SS**THydrogen-bonded Turntrans-106-24.4-172.9-174.90000113.8T431T431-V433 VanDerWaalsContact C-N 3.27Å; T431-V433 PolarHBondContact O-N 2.69Å
434E43.1Very low46.2Very low115 Ų115114.2 Ų114.254%0.53766%0.659SS.*SBendtrans-81-18.2174.6-84.8-156.9137.400113.8R438E434-R438 PolarHBondContact O-N 3.23Å; E434-R438 IonicContact OE1-NH2 2.8Å; E434-R438 PolarHBondContact OE1-NH2 2.86Å; E434-R438 IonicContact OE2-CZ 3.49Å; E434-R438 IonicContact OE2-NH2 3.87Å; E434-R438 PolarHBondContact OE2-NH2 2.79Å; E434-R438 VanDerWaalsContact OE2-NH2 3.07Å
435T51Low48Very low90 Ų90108.9 Ų108.955%0.55264%0.64SS**Hα-helixtrans-73-32.8-172.4-17.10000112.6A439T435-A439 WeakPolarHBondContact O-CB 3.41Å; T435-A439 PolarHBondContact O-N 3.07Å
436G50.8Low49.9Very low50 Ų50110.8 Ų110.852%0.51564%0.635SS.*Hα-helixtrans-69.4-38.3-179.600000113.6S440G436-S440 VanDerWaalsContact O-CB 3.27Å; G436-S440 WeakPolarHBondContact O-CB 3.35Å; G436-S440 PolarHBondContact O-N 3.45Å; G436-S440 PolarHBondContact O-OG 3.39Å
437A52Low51.6Low59 Ų59107.2 Ų107.249%0.48862%0.616SS.*Hα-helixtrans-73.5-39.6176.800000111.9S440 V441A437-S440 WeakPolarHBondContact CA-OG 3.47Å; A437-S440 PolarHBondContact O-OG 3.38Å; A437-S440 VanDerWaalsContact O-OG 3.05Å; A437-V441 VanDerWaalsContact O-CB 3.27Å; A437-V441 WeakPolarHBondContact O-CB 3.43Å; A437-V441 WeakPolarHBondContact O-CG2 3.45Å; A437-V441 PolarHBondContact O-N 3.02Å
438R55.9Low53.3Low167 Ų167103.3 Ų103.363%0.6360%0.596SS**Hα-helixtrans-71.3-36.8175.4-69.8-172-172.1161.114.8112.5E434 A442E434-R438 PolarHBondContact O-N 3.23Å; E434-R438 IonicContact OE1-NH2 2.8Å; E434-R438 PolarHBondContact OE1-NH2 2.86Å; E434-R438 IonicContact OE2-CZ 3.49Å; E434-R438 IonicContact OE2-NH2 3.87Å; E434-R438 PolarHBondContact OE2-NH2 2.79Å; E434-R438 VanDerWaalsContact OE2-NH2 3.07Å; R438-A442 VanDerWaalsContact O-CB 3.26Å; R438-A442 WeakPolarHBondContact O-CB 3.4Å; R438-A442 PolarHBondContact O-N 2.75Å
439A58.9Low55.2Low47 Ų4795.7 Ų95.739%0.38857%0.573SS.*Hα-helixtrans-68.3-41.4175.300000112.1T435 A442 Q443T435-A439 WeakPolarHBondContact O-CB 3.41Å; T435-A439 PolarHBondContact O-N 3.07Å; A439-A442 PolarHBondContact O-N 3.44Å; A439-Q443 WeakPolarHBondContact O-CB 3.42Å; A439-Q443 WeakPolarHBondContact O-CG 3.08Å; A439-Q443 PolarHBondContact O-N 3.23Å
440S60.8Low56.6Low62 Ų6291 Ų9143%0.43455%0.545SS..Hα-helixtrans-68.8-37.2175.563.70000112.3G436 A437 Q443 L444G436-S440 VanDerWaalsContact O-CB 3.27Å; G436-S440 WeakPolarHBondContact O-CB 3.35Å; G436-S440 PolarHBondContact O-N 3.45Å; G436-S440 PolarHBondContact O-OG 3.39Å; A437-S440 WeakPolarHBondContact CA-OG 3.47Å; A437-S440 PolarHBondContact O-OG 3.38Å; A437-S440 VanDerWaalsContact O-OG 3.05Å; S440-Q443 PolarHBondContact O-N 3.42Å; S440-L444 WeakPolarHBondContact O-CB 3.36Å; S440-L444 PolarHBondContact O-N 2.92Å
441V65.2Low58.3Low94 Ų9487.8 Ų87.857%0.5753%0.528SS*.Hα-helixtrans-66-38.5172170.10000111.3A437 L444 S445A437-V441 VanDerWaalsContact O-CB 3.27Å; A437-V441 WeakPolarHBondContact O-CB 3.43Å; A437-V441 WeakPolarHBondContact O-CG2 3.45Å; A437-V441 PolarHBondContact O-N 3.02Å; V441-L444 PolarHBondContact O-N 3.48Å; V441-S445 WeakPolarHBondContact O-CB 3.4Å; V441-S445 PolarHBondContact O-N 2.66Å
442A65.8Low60.1Low46 Ų4691.8 Ų91.838%0.3853%0.531SS..Hα-helixtrans-66.8-43.4174.900000111.8R438 A439 S445 M446R438-A442 VanDerWaalsContact O-CB 3.26Å; R438-A442 WeakPolarHBondContact O-CB 3.4Å; R438-A442 PolarHBondContact O-N 2.75Å; A439-A442 PolarHBondContact O-N 3.44Å; A442-S445 PolarHBondContact O-N 3.06Å; A442-M446 WeakPolarHBondContact O-CB 3.37Å; A442-M446 VanDerWaalsContact O-CG 3.31Å; A442-M446 WeakPolarHBondContact O-CG 3.45Å; A442-M446 PolarHBondContact O-N 2.83Å
443Q67.9Low61.6Low131 Ų13189.6 Ų89.661%0.61252%0.518SS*.Hα-helixtrans-63.4-42.6174.1-75.8176.2-3100112A439 S440 M446 A447A439-Q443 WeakPolarHBondContact O-CB 3.42Å; A439-Q443 WeakPolarHBondContact O-CG 3.08Å; A439-Q443 PolarHBondContact O-N 3.23Å; S440-Q443 PolarHBondContact O-N 3.42Å; Q443-M446 HydrophobicContact CG-CE 4.44Å; Q443-M446 PolarHBondContact O-N 3.01Å; Q443-A447 VanDerWaalsContact O-CB 3.28Å; Q443-A447 WeakPolarHBondContact O-CB 3.2Å; Q443-A447 PolarHBondContact O-N 2.72Å
444L66.3Low63.2Low108 Ų10883.6 Ų83.657%0.56548%0.482SS*.Hα-helixtrans-64.5-41.1175.1-173.373.4000111.2S440 V441 A447 L448S440-L444 WeakPolarHBondContact O-CB 3.36Å; S440-L444 PolarHBondContact O-N 2.92Å; V441-L444 PolarHBondContact O-N 3.48Å; L444-A447 PolarHBondContact O-N 3.12Å; L444-L448 HydrophobicContact CD1-CD1 4.01Å; L444-L448 HydrophobicContact CG-CD1 3.82Å; L444-L448 VanDerWaalsContact O-CB 3.32Å; L444-L448 WeakPolarHBondContact O-CB 3.2Å; L444-L448 WeakPolarHBondContact O-CD1 3.3Å; L444-L448 PolarHBondContact O-N 2.97Å
445S68.5Low65Low81 Ų8182.2 Ų82.257%0.56647%0.474SS*.Hα-helixtrans-66.6-38176.7-173.30000112V441 A442 G449V441-S445 WeakPolarHBondContact O-CB 3.4Å; V441-S445 PolarHBondContact O-N 2.66Å; A442-S445 PolarHBondContact O-N 3.06Å; S445-G449 PolarHBondContact O-N 3.01Å
446M67.7Low66.6Low133 Ų13378.5 Ų78.566%0.65545%0.452SS*.Hα-helixtrans-69.4-42.2174.4-74-171.3-69.900111.4A442 Q443 G449 G450A442-M446 WeakPolarHBondContact O-CB 3.37Å; A442-M446 VanDerWaalsContact O-CG 3.31Å; A442-M446 WeakPolarHBondContact O-CG 3.45Å; A442-M446 PolarHBondContact O-N 2.83Å; Q443-M446 HydrophobicContact CG-CE 4.44Å; Q443-M446 PolarHBondContact O-N 3.01Å; M446-G449 PolarHBondContact O-N 3.38Å; M446-G450 PolarHBondContact O-N 2.91Å
447A66.4Low68.3Low53 Ų5380 Ų8044%0.43845%0.453SS..Hα-helixtrans-64.5-41.5174.600000111.9Q443 L444 G450 L451Q443-A447 VanDerWaalsContact O-CB 3.28Å; Q443-A447 WeakPolarHBondContact O-CB 3.2Å; Q443-A447 PolarHBondContact O-N 2.72Å; L444-A447 PolarHBondContact O-N 3.12Å; A447-G450 PolarHBondContact O-N 3.39Å; A447-L451 VanDerWaalsContact O-CB 3.3Å; A447-L451 WeakPolarHBondContact O-CB 3.4Å; A447-L451 PolarHBondContact O-N 3.1Å
448L66.2Low69.9Low96 Ų9680.8 Ų80.850%0.50345%0.448SS..Hα-helixtrans-66-38.2173-106.6103.4000112L444 L451 R452L444-L448 HydrophobicContact CD1-CD1 4.01Å; L444-L448 HydrophobicContact CG-CD1 3.82Å; L444-L448 VanDerWaalsContact O-CB 3.32Å; L444-L448 WeakPolarHBondContact O-CB 3.2Å; L444-L448 WeakPolarHBondContact O-CD1 3.3Å; L444-L448 PolarHBondContact O-N 2.97Å; L448-L451 PolarHBondContact O-N 3.24Å; L448-R452 WeakPolarHBondContact O-CB 3.41Å; L448-R452 PolarHBondContact O-N 3.4Å
449G67.1Low71.5Confident36 Ų3673.2 Ų73.237%0.37142%0.42SS..Hα-helixtrans-60.6-48.7174.600000111.6S445 M446 R452 T453S445-G449 PolarHBondContact O-N 3.01Å; M446-G449 PolarHBondContact O-N 3.38Å; G449-R452 WeakPolarHBondContact O-CB 3.39Å; G449-R452 PolarHBondContact O-N 3.02Å; G449-T453 PolarHBondContact O-N 3.32Å; G449-T453 VanDerWaalsContact O-N 3.16Å
450G67Low73Confident13 Ų1373.4 Ų73.413%0.13441%0.412CS..Hα-helixtrans-66.3-33.4174.800000113.5M446 A447 R452 T453 V454M446-G450 PolarHBondContact O-N 2.91Å; A447-G450 PolarHBondContact O-N 3.39Å; G450-R452 VanDerWaalsContact C-N 3.34Å; G450-T453 WeakPolarHBondContact CA-OG1 3.26Å; G450-T453 PolarHBondContact O-N 3.34Å; G450-T453 PolarHBondContact O-OG1 3.01Å; G450-V454 WeakPolarHBondContact O-CG2 3.37Å; G450-V454 PolarHBondContact O-N 3.3Å; G450-V454 VanDerWaalsContact O-N 3.15Å
451L67.1Low74.5Confident89 Ų8974.9 Ų74.947%0.46641%0.408SS..Hα-helixtrans-69.4-35.3174.7-160.466.3000111.4A447 L448 T453 V454 F455A447-L451 VanDerWaalsContact O-CB 3.3Å; A447-L451 WeakPolarHBondContact O-CB 3.4Å; A447-L451 PolarHBondContact O-N 3.1Å; L448-L451 PolarHBondContact O-N 3.24Å; L451-T453 VanDerWaalsContact C-N 3.32Å; L451-T453 PolarHBondContact O-N 3.05Å; L451-V454 PolarHBondContact O-N 3Å; L451-F455 HydrophobicContact CD1-CD2 3.97Å; L451-F455 HydrophobicContact CD1-CE2 3.67Å; L451-F455 HydrophobicContact CG-CD2 3.85Å; L451-F455 HydrophobicContact CG-CE2 3.95Å; L451-F455 WeakPolarHBondContact O-CD2 3.5Å; L451-F455 PolarHBondContact O-N 3.44Å
452R71.6Confident75.7Confident187 Ų18770.4 Ų70.471%0.70638%0.382SS*.Hα-helixtrans-67.2-31.9175.2-173.1178.3-179.9176.20.6112.4L448 G449 G450 F455L448-R452 WeakPolarHBondContact O-CB 3.41Å; L448-R452 PolarHBondContact O-N 3.4Å; G449-R452 WeakPolarHBondContact O-CB 3.39Å; G449-R452 PolarHBondContact O-N 3.02Å; G450-R452 VanDerWaalsContact C-N 3.34Å; R452-F455 CarbonylContact O-C 3.58Å
453T72.3Confident77.1Confident90 Ų9069.8 Ų69.855%0.55237%0.372SS*.Hα-helixtrans-72.9-33173.552.60000111.8G449 G450 L451G449-T453 PolarHBondContact O-N 3.32Å; G449-T453 VanDerWaalsContact O-N 3.16Å; G450-T453 WeakPolarHBondContact CA-OG1 3.26Å; G450-T453 PolarHBondContact O-N 3.34Å; G450-T453 PolarHBondContact O-OG1 3.01Å; L451-T453 VanDerWaalsContact C-N 3.32Å; L451-T453 PolarHBondContact O-N 3.05Å
454V76.8Confident78.4Confident9 Ų964.7 Ų64.76%0.05535%0.348CS..Hα-helixtrans-70.5-45.6174.6173.40000111.9F203 A207 F210 G450 L451 S456F203-V454 HydrophobicContact CD2-CG1 3.81Å; F203-V454 WeakPolarHBondContact CD2-O 3.42Å; F203-V454 HydrophobicContact CE2-CG1 3.52Å; A207-V454 HydrophobicContact CB-CG1 3.95Å; F210-V454 HydrophobicContact CB-CG2 3.59Å; F210-V454 HydrophobicContact CD1-CG2 4.39Å; F210-V454 HydrophobicContact CD2-CG2 4.35Å; F210-V454 HydrophobicContact CG-CG2 3.86Å; G450-V454 WeakPolarHBondContact O-CG2 3.37Å; G450-V454 PolarHBondContact O-N 3.3Å; G450-V454 VanDerWaalsContact O-N 3.15Å; L451-V454 PolarHBondContact O-N 3Å; V454-S456 PolarHBondContact O-N 2.91Å; V454-S456 VanDerWaalsContact O-N 3.16Å
455F80.9Confident79.7Confident85 Ų8560 Ų6037%0.37332%0.324SS..SBendtrans-88.775.1177-71.8-80.9000111.1F203 L451 R452 L459 F460F203-F455 HydrophobicContact CE2-CE1 4.28Å; F203-F455 HydrophobicContact CE2-CZ 4.45Å; L451-F455 HydrophobicContact CD1-CD2 3.97Å; L451-F455 HydrophobicContact CD1-CE2 3.67Å; L451-F455 HydrophobicContact CG-CD2 3.85Å; L451-F455 HydrophobicContact CG-CE2 3.95Å; L451-F455 WeakPolarHBondContact O-CD2 3.5Å; L451-F455 PolarHBondContact O-N 3.44Å; R452-F455 CarbonylContact O-C 3.58Å; F455-L459 HydrophobicContact CD1-CD2 3.85Å; F455-L459 HydrophobicContact CE1-CD2 4.33Å; F455-F460 HydrophobicContact CB-CE2 3.71Å; F455-F460 HydrophobicContact CB-CZ 3.78Å; F455-F460 HydrophobicContact CD1-CE1 4.5Å; F455-F460 HydrophobicContact CD1-CZ 4.03Å; F455-F460 HydrophobicContact CG-CZ 4.21Å; F455-F460 WeakPolarHBondContact O-CE2 3.33Å
456S84.1Confident80.9Confident12 Ų1256.1 Ų56.18%0.08430%0.297CS..  trans-70155.4-178.272.70000112.9N202 V454 L458 L459 F460N202-S456 WeakPolarHBondContact OD1-CB 3.23Å; N202-S456 PolarHBondContact OD1-OG 3.47Å; V454-S456 PolarHBondContact O-N 2.91Å; V454-S456 VanDerWaalsContact O-N 3.16Å; S456-L458 PolarHBondContact O-N 2.93Å; S456-L458 VanDerWaalsContact O-N 3.14Å; S456-L459 PolarHBondContact O-N 3.46Å; S456-L459 VanDerWaalsContact O-N 3.16Å; S456-L459 PolarHBondContact OG-N 2.83Å; S456-F460 WeakPolarHBondContact O-CD2 3.48Å; S456-F460 PolarHBondContact O-N 2.87Å
457P85.2Confident82.3Confident83 Ų8351.3 Ų51.354%0.53927%0.272SS..Hα-helixtrans-54.8-28.7170.8-26.735.5000113.3L394 F460 R461L394-P457 VanDerWaalsContact O-CA 3.3Å; L394-P457 WeakPolarHBondContact O-CA 3.24Å; L394-P457 WeakPolarHBondContact O-CB 3.39Å; P457-F460 PolarHBondContact O-N 3.46Å; P457-R461 VanDerWaalsContact O-CB 3.3Å; P457-R461 WeakPolarHBondContact O-CB 3.4Å; P457-R461 PolarHBondContact O-N 3.44Å
458L86.8Confident83.7Confident75 Ų7548.9 Ų48.939%0.39325%0.252SS..Hα-helixtrans-66.3-42.4179.4-141.175.4000111.8N202 S456 R461 G462N202-L458 HydrophobicContact CB-CD2 4.03Å; S456-L458 PolarHBondContact O-N 2.93Å; S456-L458 VanDerWaalsContact O-N 3.14Å; L458-R461 PolarHBondContact O-N 3.25Å; L458-G462 PolarHBondContact O-N 2.85Å
459L89.4Confident85.1Confident7 Ų744.9 Ų44.94%0.03723%0.23CC..Hα-helixtrans-63.2-47174.417868.4000111.1F203 F455 S456 G462 L463F203-L459 HydrophobicContact CB-CB 4.48Å; F203-L459 HydrophobicContact CB-CD1 4.06Å; F203-L459 HydrophobicContact CB-CD2 4.03Å; F203-L459 HydrophobicContact CB-CG 4.41Å; F203-L459 HydrophobicContact CD2-CD2 3.67Å; F203-L459 HydrophobicContact CE2-CD2 4.4Å; F203-L459 HydrophobicContact CG-CD1 4.48Å; F203-L459 HydrophobicContact CG-CD2 3.97Å; F455-L459 HydrophobicContact CD1-CD2 3.85Å; F455-L459 HydrophobicContact CE1-CD2 4.33Å; S456-L459 PolarHBondContact O-N 3.46Å; S456-L459 VanDerWaalsContact O-N 3.16Å; S456-L459 PolarHBondContact OG-N 2.83Å; L459-G462 PolarHBondContact O-N 3.49Å; L459-L463 HydrophobicContact CD1-CD1 4.04Å; L459-L463 HydrophobicContact CD1-CG 4.24Å; L459-L463 HydrophobicContact CD2-CD1 4.39Å; L459-L463 HydrophobicContact CG-CD1 3.88Å; L459-L463 HydrophobicContact CG-CG 4.42Å; L459-L463 WeakPolarHBondContact O-CB 3.32Å; L459-L463 WeakPolarHBondContact O-CG 3.45Å; L459-L463 PolarHBondContact O-N 3.05Å
460F90.4Very high86.5Confident51 Ų5143.1 Ų43.122%0.22421%0.212CC..Hα-helixtrans-65.5-38.8179.6-70.8-57000112.4L394 F455 S456 P457 G462 L463 F464L394-F460 HydrophobicContact CB-CB 3.71Å; L394-F460 HydrophobicContact CB-CD2 4.23Å; L394-F460 HydrophobicContact CB-CG 4.01Å; L394-F460 HydrophobicContact CD1-CD1 4.29Å; L394-F460 HydrophobicContact CD1-CG 4.32Å; F455-F460 HydrophobicContact CB-CE2 3.71Å; F455-F460 HydrophobicContact CB-CZ 3.78Å; F455-F460 HydrophobicContact CD1-CE1 4.5Å; F455-F460 HydrophobicContact CD1-CZ 4.03Å; F455-F460 HydrophobicContact CG-CZ 4.21Å; F455-F460 WeakPolarHBondContact O-CE2 3.33Å; S456-F460 WeakPolarHBondContact O-CD2 3.48Å; S456-F460 PolarHBondContact O-N 2.87Å; P457-F460 PolarHBondContact O-N 3.46Å; F460-G462 PolarHBondContact O-N 3.34Å; F460-L463 PolarHBondContact O-N 3.38Å; F460-F464 HydrophobicContact CB-CD2 4.05Å; F460-F464 HydrophobicContact CB-CE2 4.22Å; F460-F464 HydrophobicContact CD1-CD2 4.27Å; F460-F464 AromaticContact CD1-CE2 3.68Å; F460-F464 HydrophobicContact CD1-CE2 3.68Å; F460-F464 HydrophobicContact CE1-CE2 4.49Å; F460-F464 HydrophobicContact CG-CE2 4.3Å; F460-F464 WeakPolarHBondContact O-CB 3.39Å; F460-F464 VanDerWaalsContact O-CD2 3.25Å; F460-F464 WeakPolarHBondContact O-CD2 3.32Å; F460-F464 PolarHBondContact O-N 3.25Å
461R91.5Very high88Confident93 Ų9342.7 Ų42.735%0.35121%0.207SC..Hα-helixtrans-55.6-52171.7-173.9175.6176.9-172.41.2110.1D311 H397 P457 L458 L463 S465D311-R461 IonicContact OD2-CZ 2.68Å; D311-R461 IonicContact OD2-NH2 2.74Å; D311-R461 PolarHBondContact OD2-NH2 3.41Å; H397-R461 PolarHBondContact CE1-NE 2.8Å; P457-R461 VanDerWaalsContact O-CB 3.3Å; P457-R461 WeakPolarHBondContact O-CB 3.4Å; P457-R461 PolarHBondContact O-N 3.44Å; L458-R461 PolarHBondContact O-N 3.25Å; R461-L463 PolarHBondContact O-N 3.02Å; R461-S465 WeakPolarHBondContact O-CB 3.11Å; R461-S465 PolarHBondContact O-N 3.43Å
462G91.6Very high89.3Confident1 Ų138.5 Ų38.51%0.0119%0.185CC..Hα-helixtrans-56.8-50.9177.400000113.7F194 G195 L458 L459 F460 F466F194-G462 WeakPolarHBondContact O-CA 3.36Å; G195-G462 WeakPolarHBondContact O-CA 3.41Å; L458-G462 PolarHBondContact O-N 2.85Å; L459-G462 PolarHBondContact O-N 3.49Å; F460-G462 PolarHBondContact O-N 3.34Å; G462-F466 VanDerWaalsContact O-CB 3.32Å; G462-F466 WeakPolarHBondContact O-CB 3.38Å; G462-F466 PolarHBondContact O-N 3.43Å
463L94.1Very high90.5Very high33 Ų3329.8 Ų29.817%0.17315%0.153CC..Hα-helixtrans-66.1-52.3-177.4-73.1174.3000112.7L196 F227 L231 L459 F460 R461 S465 F466 F467L196-L463 HydrophobicContact CD1-CD2 3.93Å; F227-L463 HydrophobicContact CE2-CD2 4.35Å; F227-L463 HydrophobicContact CZ-CD2 3.92Å; L231-L463 HydrophobicContact CD1-CD2 4.49Å; L459-L463 HydrophobicContact CD1-CD1 4.04Å; L459-L463 HydrophobicContact CD1-CG 4.24Å; L459-L463 HydrophobicContact CD2-CD1 4.39Å; L459-L463 HydrophobicContact CG-CD1 3.88Å; L459-L463 HydrophobicContact CG-CG 4.42Å; L459-L463 WeakPolarHBondContact O-CB 3.32Å; L459-L463 WeakPolarHBondContact O-CG 3.45Å; L459-L463 PolarHBondContact O-N 3.05Å; F460-L463 PolarHBondContact O-N 3.38Å; R461-L463 PolarHBondContact O-N 3.02Å; L463-S465 VanDerWaalsContact C-N 3.35Å; L463-S465 PolarHBondContact O-N 2.98Å; L463-F466 PolarHBondContact O-N 3.07Å; L463-F467 HydrophobicContact CB-CD2 4.4Å; L463-F467 HydrophobicContact CB-CE2 4.24Å; L463-F467 HydrophobicContact CD2-CE2 4.29Å; L463-F467 WeakPolarHBondContact O-CD2 3.45Å; L463-F467 PolarHBondContact O-N 3.05Å
464F94.7Very high91.7Very high24 Ų2425.5 Ų25.511%0.10513%0.126CC..Hα-helixtrans-71.8-30.4-176.9-72.7-67.9000112.4T387 L390 L391 L394 F460 T468T387-F464 HydrophobicContact CG2-CD1 3.83Å; L390-F464 HydrophobicContact CB-CD1 3.93Å; L390-F464 HydrophobicContact CB-CD2 4.33Å; L390-F464 HydrophobicContact CB-CE1 3.74Å; L390-F464 HydrophobicContact CB-CE2 4.18Å; L390-F464 HydrophobicContact CB-CG 4.23Å; L390-F464 HydrophobicContact CB-CZ 3.89Å; L390-F464 HydrophobicContact CD1-CD1 4.45Å; L390-F464 HydrophobicContact CD1-CE1 3.61Å; L390-F464 HydrophobicContact CD1-CZ 3.86Å; L390-F464 HydrophobicContact CG-CE1 4.3Å; L390-F464 HydrophobicContact CG-CZ 4.37Å; L391-F464 HydrophobicContact CB-CB 3.79Å; L391-F464 HydrophobicContact CD1-CB 3.95Å; L391-F464 HydrophobicContact CG-CB 4.42Å; L394-F464 HydrophobicContact CB-CE2 4.44Å; L394-F464 HydrophobicContact CD1-CD2 4.34Å; L394-F464 HydrophobicContact CD1-CE2 3.49Å; L394-F464 VanDerWaalsContact CD1-CE2 3.49Å; L394-F464 HydrophobicContact CD1-CZ 4.06Å; F460-F464 HydrophobicContact CB-CD2 4.05Å; F460-F464 HydrophobicContact CB-CE2 4.22Å; F460-F464 HydrophobicContact CD1-CD2 4.27Å; F460-F464 AromaticContact CD1-CE2 3.68Å; F460-F464 HydrophobicContact CD1-CE2 3.68Å; F460-F464 HydrophobicContact CE1-CE2 4.49Å; F460-F464 HydrophobicContact CG-CE2 4.3Å; F460-F464 WeakPolarHBondContact O-CB 3.39Å; F460-F464 VanDerWaalsContact O-CD2 3.25Å; F460-F464 WeakPolarHBondContact O-CD2 3.32Å; F460-F464 PolarHBondContact O-N 3.25Å; F464-T468 VanDerWaalsContact O-CB 3.23Å; F464-T468 WeakPolarHBondContact O-CB 3.4Å; F464-T468 PolarHBondContact O-N 3.26Å; F464-T468 PolarHBondContact O-OG1 3.25Å
465S93.8Very high92.6Very high9 Ų925 Ų256%0.06312%0.124CC..Hα-helixtrans-59.8-51.1170.1176.50000110.1F194 W283 R461 L463 T468 W469F194-S465 PolarHBondContact O-OG 2.82Å; W283-S465 PolarHBondContact NE1-OG 2.96Å; R461-S465 WeakPolarHBondContact O-CB 3.11Å; R461-S465 PolarHBondContact O-N 3.43Å; L463-S465 VanDerWaalsContact C-N 3.35Å; L463-S465 PolarHBondContact O-N 2.98Å; S465-T468 PolarHBondContact O-N 3.06Å; S465-W469 WeakPolarHBondContact O-CB 3.24Å; S465-W469 PolarHBondContact O-N 2.89Å; S465-W469 VanDerWaalsContact O-N 3.07Å
466F95.3Very high93.3Very high0 Ų023.2 Ų23.20%012%0.116CC..Hα-helixtrans-63-45.5176.7175.8-101.5000113I184 L185 F194 L231 C235 G462 L463 W469 W470I184-F466 HydrophobicContact CG2-CE2 4.21Å; L185-F466 HydrophobicContact CD2-CD2 4.44Å; L185-F466 HydrophobicContact CD2-CE1 4.31Å; L185-F466 HydrophobicContact CD2-CE2 3.76Å; L185-F466 HydrophobicContact CD2-CZ 3.67Å; L185-F466 HydrophobicContact CG-CE2 4.4Å; L185-F466 HydrophobicContact CG-CZ 4.16Å; F194-F466 HydrophobicContact CB-CB 4.38Å; F194-F466 HydrophobicContact CD1-CB 4.38Å; F194-F466 HydrophobicContact CD1-CD2 4.39Å; F194-F466 AromaticContact CD2-CD2 3.95Å; F194-F466 HydrophobicContact CD2-CD2 3.95Å; F194-F466 HydrophobicContact CE1-CD2 4.47Å; F194-F466 AromaticContact CE2-CD2 3.99Å; F194-F466 HydrophobicContact CE2-CD2 3.99Å; F194-F466 HydrophobicContact CE2-CE2 4.44Å; F194-F466 HydrophobicContact CG-CB 4.31Å; F194-F466 HydrophobicContact CG-CD2 4.15Å; F194-F466 HydrophobicContact CZ-CD2 4.27Å; L231-F466 HydrophobicContact CD1-CD1 3.94Å; L231-F466 HydrophobicContact CD1-CE1 3.72Å; L231-F466 HydrophobicContact CD2-CD1 3.84Å; L231-F466 HydrophobicContact CD2-CE1 3.67Å; L231-F466 HydrophobicContact CD2-CZ 4.31Å; L231-F466 HydrophobicContact CG-CD1 4.08Å; L231-F466 HydrophobicContact CG-CE1 3.56Å; L231-F466 HydrophobicContact CG-CZ 4.31Å; C235-F466 WeakPolarHBondContact SG-CE1 3.37Å; C235-F466 VanDerWaalsContact SG-CZ 3.56Å; G462-F466 VanDerWaalsContact O-CB 3.32Å; G462-F466 WeakPolarHBondContact O-CB 3.38Å; G462-F466 PolarHBondContact O-N 3.43Å; L463-F466 PolarHBondContact O-N 3.07Å; F466-W469 PolarHBondContact O-N 2.84Å; F466-W470 HydrophobicContact CZ-CE3 4.33Å; F466-W470 VanDerWaalsContact O-CB 3.23Å; F466-W470 WeakPolarHBondContact O-CB 3.28Å; F466-W470 PolarHBondContact O-N 3.12Å
467F95.8Very high93.9Very high31 Ų3123.6 Ų23.614%0.13612%0.118CC..Hα-helixtrans-65.3-41.1178.6-75-57000112.7L231 L234 I238 T387 L463 W469 W470 I471L231-F467 HydrophobicContact CD1-CE1 3.71Å; L231-F467 HydrophobicContact CD1-CE2 4.28Å; L231-F467 HydrophobicContact CD1-CZ 3.41Å; L231-F467 VanDerWaalsContact CD1-CZ 3.41Å; L234-F467 HydrophobicContact CD2-CE1 3.57Å; L234-F467 HydrophobicContact CD2-CE2 4.49Å; L234-F467 HydrophobicContact CD2-CZ 3.38Å; L234-F467 HydrophobicContact CG-CE1 4.02Å; L234-F467 HydrophobicContact CG-CZ 4.32Å; I238-F467 HydrophobicContact CD1-CD1 4.03Å; I238-F467 HydrophobicContact CD1-CE1 4.12Å; T387-F467 HydrophobicContact CG2-CB 3.93Å; L463-F467 HydrophobicContact CB-CD2 4.4Å; L463-F467 HydrophobicContact CB-CE2 4.24Å; L463-F467 HydrophobicContact CD2-CE2 4.29Å; L463-F467 WeakPolarHBondContact O-CD2 3.45Å; L463-F467 PolarHBondContact O-N 3.05Å; F467-W469 VanDerWaalsContact C-N 3.32Å; F467-W469 PolarHBondContact O-N 3.19Å; F467-W470 PolarHBondContact O-N 3.08Å; F467-I471 WeakPolarHBondContact O-CB 3.33Å; F467-I471 WeakPolarHBondContact O-CD1 3.42Å; F467-I471 WeakPolarHBondContact O-CG1 3.46Å; F467-I471 PolarHBondContact O-N 3.4Å
468T95.5Very high94.3Very high2 Ų219.6 Ų19.61%0.0129%0.093CC..Hα-helixtrans-59.1-47.7176.6-590000110.1W283 I318 L384 T387 F464 S465 A472W283-T468 HydrophobicContact CH2-CG2 4.46Å; I318-T468 HydrophobicContact CD1-CG2 3.56Å; L384-T468 HydrophobicContact CD1-CG2 3.83Å; T387-T468 VanDerWaalsContact CG2-OG1 3.3Å; T387-T468 WeakPolarHBondContact CG2-OG1 3.39Å; F464-T468 VanDerWaalsContact O-CB 3.23Å; F464-T468 WeakPolarHBondContact O-CB 3.4Å; F464-T468 PolarHBondContact O-N 3.26Å; F464-T468 PolarHBondContact O-OG1 3.25Å; S465-T468 PolarHBondContact O-N 3.06Å; T468-A472 PolarHBondContact O-N 2.76Å
469W96.1Very high94.7Very high12 Ų1216.1 Ų16.15%0.0458%0.075CC..Hα-helixtrans-62.1-45174.7-177.487.4000112.5I184 L192 F194 V280 W283 S465 F466 F467 I471 A472 A473I184-W469 HydrophobicContact CB-CH2 4.48Å; I184-W469 HydrophobicContact CB-CZ3 4.43Å; I184-W469 HydrophobicContact CD1-CH2 3.81Å; I184-W469 HydrophobicContact CG1-CH2 3.86Å; I184-W469 HydrophobicContact CG1-CZ3 4.16Å; I184-W469 HydrophobicContact CG2-CH2 3.84Å; I184-W469 HydrophobicContact CG2-CZ3 3.66Å; L192-W469 HydrophobicContact CD2-CZ2 4.46Å; F194-W469 HydrophobicContact CD1-CB 4.5Å; F194-W469 HydrophobicContact CE1-CB 3.74Å; F194-W469 AromaticContact CE1-CD1 3.99Å; F194-W469 AromaticContact CE1-CD2 3.66Å; F194-W469 HydrophobicContact CE1-CD2 3.66Å; F194-W469 HydrophobicContact CE1-CE3 4.08Å; F194-W469 AromaticContact CE1-CG 3.5Å; F194-W469 HydrophobicContact CE1-CG 3.5Å; F194-W469 AromaticContact CZ-CD2 3.57Å; F194-W469 HydrophobicContact CZ-CD2 3.57Å; F194-W469 AromaticContact CZ-CE2 3.92Å; F194-W469 AromaticContact CZ-CE3 3.69Å; F194-W469 HydrophobicContact CZ-CE3 3.69Å; F194-W469 AromaticContact CZ-CG 3.96Å; F194-W469 HydrophobicContact CZ-CG 3.96Å; F194-W469 HydrophobicContact CZ-CH2 4.49Å; F194-W469 HydrophobicContact CZ-CZ2 4.36Å; F194-W469 HydrophobicContact CZ-CZ3 4.18Å; V280-W469 HydrophobicContact CG1-CZ2 3.94Å; V280-W469 PolarHBondContact O-NE1 3.24Å; W283-W469 VanDerWaalsContact CB-CD1 3.49Å; W283-W469 HydrophobicContact CB-CG 4.33Å; W283-W469 HydrophobicContact CD2-CB 4.46Å; W283-W469 HydrophobicContact CG-CB 4.39Å; W283-W469 AromaticContact CG-CD1 3.84Å; W283-W469 HydrophobicContact CG-CG 4.39Å; S465-W469 WeakPolarHBondContact O-CB 3.24Å; S465-W469 PolarHBondContact O-N 2.89Å; S465-W469 VanDerWaalsContact O-N 3.07Å; F466-W469 PolarHBondContact O-N 2.84Å; F467-W469 VanDerWaalsContact C-N 3.32Å; F467-W469 PolarHBondContact O-N 3.19Å; W469-I471 PolarHBondContact O-N 3.11Å; W469-A472 PolarHBondContact O-N 2.68Å; W469-A473 HydrophobicContact CD2-CB 4.47Å; W469-A473 HydrophobicContact CE3-CB 4.23Å; W469-A473 HydrophobicContact CH2-CB 4.17Å; W469-A473 HydrophobicContact CZ2-CB 4.43Å; W469-A473 HydrophobicContact CZ3-CB 4.06Å; W469-A473 VanDerWaalsContact O-CB 3.32Å; W469-A473 WeakPolarHBondContact O-CB 3.34Å; W469-A473 PolarHBondContact O-N 3.49Å
470W97.3Very high94.9Very high0 Ų020.1 Ų20.10%010%0.096CC..Hα-helixtrans-62.8-44.5-178-177-104.6000112.1F177 K180 A181 C235 F466 F467 A472 A473 C474F177-W470 HydrophobicContact CB-CZ2 4.09Å; F177-W470 HydrophobicContact CD1-CH2 4.15Å; F177-W470 AromaticContact CD1-CZ2 3.83Å; F177-W470 HydrophobicContact CD1-CZ2 3.83Å; F177-W470 HydrophobicContact CG-CZ2 4.35Å; F177-W470 WeakPolarHBondContact O-CH2 3.25Å; K180-W470 HydrophobicContact CB-CH2 4.11Å; K180-W470 HydrophobicContact CD-CH2 4.04Å; K180-W470 HydrophobicContact CD-CZ3 4.3Å; K180-W470 HydrophobicContact CG-CH2 4.03Å; K180-W470 HydrophobicContact CG-CZ3 4.22Å; A181-W470 HydrophobicContact CB-CH2 3.53Å; A181-W470 HydrophobicContact CB-CZ2 3.96Å; A181-W470 HydrophobicContact CB-CZ3 3.97Å; C235-W470 VanDerWaalsContact CA-NE1 3.3Å; C235-W470 HydrophobicContact CB-CD2 4Å; C235-W470 HydrophobicContact CB-CG 4.42Å; C235-W470 HydrophobicContact CB-CH2 4.33Å; C235-W470 HydrophobicContact CB-CZ2 3.58Å; C235-W470 PolarHBondContact O-NE1 3.34Å; F466-W470 HydrophobicContact CZ-CE3 4.33Å; F466-W470 VanDerWaalsContact O-CB 3.23Å; F466-W470 WeakPolarHBondContact O-CB 3.28Å; F466-W470 PolarHBondContact O-N 3.12Å; F467-W470 PolarHBondContact O-N 3.08Å; W470-A472 VanDerWaalsContact C-N 3.35Å; W470-A472 PolarHBondContact O-N 3.01Å; W470-A473 PolarHBondContact O-N 3.36Å; W470-C474 PolarHBondContact NE1-SG 2.98Å; W470-C474 WeakPolarHBondContact O-CB 3.49Å; W470-C474 PolarHBondContact O-N 3.43Å; W470-C474 PolarHBondContact O-SG 3.31Å
471I96.9Very high95Very high3 Ų322 Ų222%0.01510%0.104CC..Hα-helixtrans-59-47.6176.4-68164.1000110I238 L242 M383 L384 T387 F467 W469 A473 C474 L475I238-I471 HydrophobicContact CG2-CG1 4.25Å; L242-I471 HydrophobicContact CD1-CG2 4.2Å; M383-I471 HydrophobicContact CE-CB 4.4Å; M383-I471 HydrophobicContact CE-CD1 3.91Å; M383-I471 HydrophobicContact CE-CG1 3.77Å; M383-I471 HydrophobicContact CE-CG2 3.77Å; M383-I471 HydrophobicContact CG-CD1 3.84Å; M383-I471 HydrophobicContact SD-CD1 4.22Å; L384-I471 HydrophobicContact CB-CG2 4.25Å; L384-I471 HydrophobicContact CD1-CB 4.36Å; L384-I471 HydrophobicContact CD1-CG2 4.16Å; T387-I471 HydrophobicContact CG2-CD1 4.42Å; F467-I471 WeakPolarHBondContact O-CB 3.33Å; F467-I471 WeakPolarHBondContact O-CD1 3.42Å; F467-I471 WeakPolarHBondContact O-CG1 3.46Å; F467-I471 PolarHBondContact O-N 3.4Å; W469-I471 PolarHBondContact O-N 3.11Å; I471-A473 PolarHBondContact O-N 3.43Å; I471-C474 PolarHBondContact O-N 3Å; I471-L475 HydrophobicContact CG2-CD1 4.1Å; I471-L475 WeakPolarHBondContact O-CB 3.17Å; I471-L475 VanDerWaalsContact O-CG 3.3Å; I471-L475 WeakPolarHBondContact O-CG 3.46Å; I471-L475 PolarHBondContact O-N 2.8Å
472A96.3Very high95Very high1 Ų117.6 Ų17.61%0.0089%0.087CC..Hα-helixtrans-62.5-41.7176.500000112P276 M279 V280 T468 W469 W470 L475 F476P276-A472 HydrophobicContact CB-CB 4.47Å; P276-A472 WeakPolarHBondContact CB-O 3.42Å; M279-A472 HydrophobicContact CB-CB 3.81Å; M279-A472 HydrophobicContact SD-CB 4.09Å; V280-A472 HydrophobicContact CG2-CB 3.99Å; T468-A472 PolarHBondContact O-N 2.76Å; W469-A472 PolarHBondContact O-N 2.68Å; W470-A472 VanDerWaalsContact C-N 3.35Å; W470-A472 PolarHBondContact O-N 3.01Å; A472-L475 PolarHBondContact O-N 3.06Å; A472-F476 WeakPolarHBondContact O-CB 3.24Å; A472-F476 PolarHBondContact O-N 2.9Å
473A96.6Very high94.9Very high4 Ų418.8 Ų18.83%0.0339%0.093CC..Hα-helixtrans-66-37.917800000112.5K180 V280 W469 W470 I471 S477K180-A473 PolarHBondContact NZ-O 3.2Å; K180-A473 VanDerWaalsContact NZ-O 3.14Å; V280-A473 HydrophobicContact CG2-CB 3.76Å; W469-A473 HydrophobicContact CD2-CB 4.47Å; W469-A473 HydrophobicContact CE3-CB 4.23Å; W469-A473 HydrophobicContact CH2-CB 4.17Å; W469-A473 HydrophobicContact CZ2-CB 4.43Å; W469-A473 HydrophobicContact CZ3-CB 4.06Å; W469-A473 VanDerWaalsContact O-CB 3.32Å; W469-A473 WeakPolarHBondContact O-CB 3.34Å; W469-A473 PolarHBondContact O-N 3.49Å; W470-A473 PolarHBondContact O-N 3.36Å; I471-A473 PolarHBondContact O-N 3.43Å; A473-S477 WeakPolarHBondContact O-CB 3.42Å; A473-S477 PolarHBondContact O-N 3.08Å; A473-S477 PolarHBondContact O-OG 3.37Å
474C96.9Very high94.7Very high0 Ų022.9 Ų22.90%011%0.11CC..Hα-helixtrans-64.8-47.5172.9-77.60000111F177 L242 W470 I471 F476 S477 T478F177-C474 VanDerWaalsContact CD1-SG 3.56Å; F177-C474 HydrophobicContact CE1-CB 4.1Å; F177-C474 VanDerWaalsContact CE1-SG 3.5Å; F177-C474 HydrophobicContact CZ-CB 4.23Å; L242-C474 HydrophobicContact CB-CB 4.38Å; L242-C474 HydrophobicContact CD1-CB 3.74Å; W470-C474 PolarHBondContact NE1-SG 2.98Å; W470-C474 WeakPolarHBondContact O-CB 3.49Å; W470-C474 PolarHBondContact O-N 3.43Å; W470-C474 PolarHBondContact O-SG 3.31Å; I471-C474 PolarHBondContact O-N 3Å; C474-F476 VanDerWaalsContact C-N 3.34Å; C474-F476 PolarHBondContact O-N 3.26Å; C474-S477 PolarHBondContact O-N 3.02Å; C474-T478 WeakPolarHBondContact O-CB 3.47Å; C474-T478 VanDerWaalsContact O-CG2 3.31Å; C474-T478 WeakPolarHBondContact O-CG2 3.1Å; C474-T478 PolarHBondContact O-N 3.4Å; C474-T478 PolarHBondContact O-OG1 3.45Å
475L95.4Very high94.3Very high0 Ų026.9 Ų26.90%013%0.125CC..Hα-helixtrans-59.5-43.5177.5-75.6172.3000112.3L242 P276 P380 I471 A472 T478 S479L242-L475 HydrophobicContact CD1-CG 4.39Å; L242-L475 HydrophobicContact CD2-CD2 4.39Å; P276-L475 HydrophobicContact CB-CB 4.13Å; P276-L475 HydrophobicContact CG-CB 4.23Å; P380-L475 HydrophobicContact CB-CD1 4.03Å; P380-L475 HydrophobicContact CB-CD2 3.7Å; P380-L475 HydrophobicContact CB-CG 4.32Å; P380-L475 HydrophobicContact CG-CD2 4.16Å; I471-L475 HydrophobicContact CG2-CD1 4.1Å; I471-L475 WeakPolarHBondContact O-CB 3.17Å; I471-L475 VanDerWaalsContact O-CG 3.3Å; I471-L475 WeakPolarHBondContact O-CG 3.46Å; I471-L475 PolarHBondContact O-N 2.8Å; A472-L475 PolarHBondContact O-N 3.06Å; L475-T478 PolarHBondContact O-OG1 2.91Å; L475-T478 VanDerWaalsContact O-OG1 3.11Å; L475-S479 WeakPolarHBondContact O-CB 3.4Å; L475-S479 PolarHBondContact O-N 3.02Å; L475-S479 PolarHBondContact O-OG 2.85Å
476F95.9Very high93.8Very high47 Ų4728.4 Ų28.421%0.20613%0.131CC..Hα-helixtrans-64.4-51.9176.3-177.5-114.8000111.6P276 L277 A472 C474 T478 S479 L480P276-F476 HydrophobicContact CB-CB 4.05Å; L277-F476 HydrophobicContact CB-CD2 3.81Å; L277-F476 HydrophobicContact CB-CE2 3.77Å; L277-F476 HydrophobicContact CB-CG 4.3Å; L277-F476 HydrophobicContact CB-CZ 4.23Å; L277-F476 HydrophobicContact CD1-CD1 4.21Å; L277-F476 HydrophobicContact CD1-CE1 3.86Å; L277-F476 HydrophobicContact CD1-CE2 4.34Å; L277-F476 HydrophobicContact CD1-CZ 3.93Å; L277-F476 HydrophobicContact CD2-CE2 4.27Å; L277-F476 HydrophobicContact CD2-CZ 4.16Å; L277-F476 HydrophobicContact CG-CE2 4.34Å; L277-F476 HydrophobicContact CG-CZ 4.33Å; A472-F476 WeakPolarHBondContact O-CB 3.24Å; A472-F476 PolarHBondContact O-N 2.9Å; C474-F476 VanDerWaalsContact C-N 3.34Å; C474-F476 PolarHBondContact O-N 3.26Å; F476-T478 PolarHBondContact O-N 3.37Å; F476-S479 PolarHBondContact O-N 2.75Å; F476-L480 HydrophobicContact CE1-CD2 4.47Å; F476-L480 HydrophobicContact CZ-CD2 4.5Å; F476-L480 WeakPolarHBondContact O-CB 3.28Å; F476-L480 PolarHBondContact O-N 2.81Å
477S95.6Very high93.1Very high19 Ų1933 Ų3313%0.13315%0.152CC..Hα-helixtrans-58.6-49.8-178.4-65.70000111.8K180 A473 C474 S479 L480 F481K180-S477 PolarHBondContact NZ-OG 3.09Å; A473-S477 WeakPolarHBondContact O-CB 3.42Å; A473-S477 PolarHBondContact O-N 3.08Å; A473-S477 PolarHBondContact O-OG 3.37Å; C474-S477 PolarHBondContact O-N 3.02Å; S477-S479 PolarHBondContact O-N 2.74Å; S477-L480 PolarHBondContact O-N 3.4Å; S477-F481 WeakPolarHBondContact O-CD2 3.18Å; S477-F481 PolarHBondContact O-N 2.95Å
478T95Very high92.1Very high0 Ų038.3 Ų38.30%017%0.173CC..Hα-helixtrans-63.3-40.4179.849.10000112.4F173 F177 G246 C474 L475 F476 F481 G482F173-T478 HydrophobicContact CE1-CG2 4.5Å; F177-T478 HydrophobicContact CE2-CG2 3.71Å; F177-T478 HydrophobicContact CZ-CG2 3.63Å; G246-T478 WeakPolarHBondContact CA-OG1 3.37Å; C474-T478 WeakPolarHBondContact O-CB 3.47Å; C474-T478 VanDerWaalsContact O-CG2 3.31Å; C474-T478 WeakPolarHBondContact O-CG2 3.1Å; C474-T478 PolarHBondContact O-N 3.4Å; C474-T478 PolarHBondContact O-OG1 3.45Å; L475-T478 PolarHBondContact O-OG1 2.91Å; L475-T478 VanDerWaalsContact O-OG1 3.11Å; F476-T478 PolarHBondContact O-N 3.37Å; T478-F481 PolarHBondContact O-N 3.18Å; T478-G482 PolarHBondContact O-N 2.95Å
479S93.9Very high90.8Very high2 Ų243.2 Ų43.21%0.01420%0.198CC..Hα-helixtrans-67.5-36.2177.3-55.10000112.1G246 A250 L475 F476 S477 G482 L483G246-S479 WeakPolarHBondContact O-CA 3.34Å; A250-S479 VanDerWaalsContact CB-O 3.24Å; A250-S479 WeakPolarHBondContact CB-O 3.42Å; L475-S479 WeakPolarHBondContact O-CB 3.4Å; L475-S479 PolarHBondContact O-N 3.02Å; L475-S479 PolarHBondContact O-OG 2.85Å; F476-S479 PolarHBondContact O-N 2.75Å; S477-S479 PolarHBondContact O-N 2.74Å; S479-G482 PolarHBondContact O-N 2.89Å; S479-L483 PolarHBondContact O-N 2.88Å
480L93.9Very high89.3Confident91 Ų9148.4 Ų48.448%0.47622%0.224SC..Hα-helixtrans-67.1-44.9175.4-174.865.2000111.8F476 S477 G482 L483 F484F476-L480 HydrophobicContact CE1-CD2 4.47Å; F476-L480 HydrophobicContact CZ-CD2 4.5Å; F476-L480 WeakPolarHBondContact O-CB 3.28Å; F476-L480 PolarHBondContact O-N 2.81Å; S477-L480 PolarHBondContact O-N 3.4Å; L480-G482 VanDerWaalsContact C-N 3.25Å; L480-G482 PolarHBondContact O-N 3.22Å; L480-L483 PolarHBondContact O-N 3.22Å; L480-F484 PolarHBondContact O-N 3.41Å
481F93Very high87.2Confident91 Ų9152.2 Ų52.240%0.39926%0.256SS..Hα-helixtrans-59.1-39.8171.2-84-72.5000111.5F173 F176 L247 S477 T478 F484 Y485F173-F481 HydrophobicContact CE1-CB 4.26Å; F173-F481 AromaticContact CE1-CD2 3.71Å; F173-F481 HydrophobicContact CE1-CD2 3.71Å; F173-F481 HydrophobicContact CE1-CE2 4.25Å; F173-F481 HydrophobicContact CE1-CG 4.02Å; F173-F481 HydrophobicContact CZ-CB 3.87Å; F173-F481 HydrophobicContact CZ-CD1 4.46Å; F173-F481 HydrophobicContact CZ-CD2 4.09Å; F173-F481 AromaticContact CZ-CG 3.9Å; F173-F481 HydrophobicContact CZ-CG 3.9Å; F176-F481 AromaticContact CE1-CE2 3.96Å; F176-F481 HydrophobicContact CE1-CE2 3.96Å; F176-F481 HydrophobicContact CE2-CE2 4.3Å; F176-F481 HydrophobicContact CE2-CZ 4.31Å; F176-F481 AromaticContact CZ-CE2 3.77Å; F176-F481 HydrophobicContact CZ-CE2 3.77Å; F176-F481 HydrophobicContact CZ-CZ 4.22Å; L247-F481 HydrophobicContact CD2-CB 4.34Å; S477-F481 WeakPolarHBondContact O-CD2 3.18Å; S477-F481 PolarHBondContact O-N 2.95Å; T478-F481 PolarHBondContact O-N 3.18Å; F481-F484 PolarHBondContact O-N 3.14Å; F481-Y485 VanDerWaalsContact O-CB 3.31Å; F481-Y485 WeakPolarHBondContact O-CB 3.39Å; F481-Y485 PolarHBondContact O-N 3.28Å
482G91.1Very high84.4Confident0 Ų058.3 Ų58.30%031%0.306CS..Hα-helixtrans-61.5-43.1175.800000112.6A250 T478 S479 L480 Y485 H486A250-G482 VanDerWaalsContact CB-C 3.47Å; T478-G482 PolarHBondContact O-N 2.95Å; S479-G482 PolarHBondContact O-N 2.89Å; L480-G482 VanDerWaalsContact C-N 3.25Å; L480-G482 PolarHBondContact O-N 3.22Å; G482-Y485 PolarHBondContact O-N 3.22Å; G482-H486 PolarHBondContact O-N 2.94Å; G482-H486 PolarHBondContact O-ND1 3.07Å
483L90.5Very high83.8Confident26 Ų2661.2 Ų61.214%0.13632%0.321CS..Hα-helixtrans-61.6-48.7174.9-78.4-175.3000111.3A250 L254 F273 S479 L480 Y485 H486 Q487A250-L483 HydrophobicContact CB-CD2 4.22Å; A250-L483 HydrophobicContact CB-CG 4.15Å; L254-L483 HydrophobicContact CD1-CD2 3.66Å; L254-L483 HydrophobicContact CD2-CD2 3.68Å; L254-L483 HydrophobicContact CG-CD2 3.5Å; L254-L483 VanDerWaalsContact CG-CD2 3.5Å; F273-L483 HydrophobicContact CD1-CD1 4.38Å; F273-L483 HydrophobicContact CE1-CD1 3.37Å; F273-L483 HydrophobicContact CE1-CG 4.26Å; F273-L483 HydrophobicContact CE2-CD1 4.01Å; F273-L483 HydrophobicContact CE2-CD2 4.41Å; F273-L483 HydrophobicContact CE2-CG 4.04Å; F273-L483 HydrophobicContact CZ-CD1 3.15Å; F273-L483 HydrophobicContact CZ-CD2 4.3Å; F273-L483 HydrophobicContact CZ-CG 3.54Å; S479-L483 PolarHBondContact O-N 2.88Å; L480-L483 PolarHBondContact O-N 3.22Å; L483-Y485 VanDerWaalsContact C-N 3.32Å; L483-Y485 PolarHBondContact O-N 2.98Å; L483-H486 PolarHBondContact O-N 2.87Å; L483-Q487 WeakPolarHBondContact O-CB 3.32Å; L483-Q487 WeakPolarHBondContact O-CG 3.44Å; L483-Q487 PolarHBondContact O-N 2.88Å
484F88.9Confident83.1Confident119 Ų11964.2 Ų64.252%0.52234%0.337SS..Hα-helixtrans-59.2-45179.1-178.3-97.5000111.4L480 F481 Y488 L489L480-F484 PolarHBondContact O-N 3.41Å; F481-F484 PolarHBondContact O-N 3.14Å; F484-Y488 AromaticContact CD2-CD2 3.54Å; F484-Y488 HydrophobicContact CD2-CD2 3.54Å; F484-Y488 HydrophobicContact CD2-CE2 4.04Å; F484-Y488 HydrophobicContact CD2-CG 4.32Å; F484-Y488 AromaticContact CE2-CD2 3.78Å; F484-Y488 HydrophobicContact CE2-CD2 3.78Å; F484-Y488 HydrophobicContact CE2-CE2 4.34Å; F484-Y488 HydrophobicContact CE2-CG 4.15Å; F484-Y488 HydrophobicContact CG-CD2 4.26Å; F484-Y488 WeakPolarHBondContact O-CB 3.18Å; F484-Y488 PolarHBondContact O-N 3.29Å; F484-L489 HydrophobicContact CE1-CD1 4.46Å
485Y87.1Confident82.4Confident107 Ų10767.7 Ų67.742%0.4236%0.355SS..Iπ-helixtrans-59.5-49.6177.8179.8-95.9000112.2F481 G482 L483 L489 M490F481-Y485 VanDerWaalsContact O-CB 3.31Å; F481-Y485 WeakPolarHBondContact O-CB 3.39Å; F481-Y485 PolarHBondContact O-N 3.28Å; G482-Y485 PolarHBondContact O-N 3.22Å; L483-Y485 VanDerWaalsContact C-N 3.32Å; L483-Y485 PolarHBondContact O-N 2.98Å; Y485-L489 HydrophobicContact CD2-CB 4.13Å; Y485-L489 HydrophobicContact CD2-CD1 3.65Å; Y485-L489 HydrophobicContact CE2-CB 4.39Å; Y485-L489 HydrophobicContact CE2-CD1 4.29Å; Y485-L489 HydrophobicContact CG-CD1 4.49Å; Y485-L489 WeakPolarHBondContact O-CA 3.41Å; Y485-L489 WeakPolarHBondContact O-CB 3.37Å; Y485-L489 PolarHBondContact O-N 2.83Å; Y485-M490 HydrophobicContact CD1-CG 4.15Å; Y485-M490 HydrophobicContact CE1-CG 3.61Å; Y485-M490 HydrophobicContact CE1-SD 4.28Å; Y485-M490 PolarHBondContact O-N 3.47Å; Y485-M490 VanDerWaalsContact O-N 3.16Å
486H82.4Confident81.6Confident41 Ų4171.7 Ų71.719%0.1938%0.376CS..Iπ-helixtrans-74-33.1-176.3-69.988000113.3Q251 L254 G482 L483Q251-H486 PolarHBondContact OE1-NE2 2.88Å; L254-H486 HydrophobicContact CD1-CB 4.02Å; G482-H486 PolarHBondContact O-N 2.94Å; G482-H486 PolarHBondContact O-ND1 3.07Å; L483-H486 PolarHBondContact O-N 2.87Å
487Q81.8Confident80.7Confident96 Ų9673.3 Ų73.345%0.44939%0.387SS..Iπ-helixtrans-80.7-33.4-179-72.6-175.5-19.300113.6L254 L483 A491L254-Q487 HydrophobicContact CD1-CG 3.95Å; L483-Q487 WeakPolarHBondContact O-CB 3.32Å; L483-Q487 WeakPolarHBondContact O-CG 3.44Å; L483-Q487 PolarHBondContact O-N 2.88Å; Q487-A491 WeakPolarHBondContact O-CB 3.48Å
488Y74.2Confident79.7Confident144 Ų14476.9 Ų76.957%0.56540%0.404SS*.Iπ-helixtrans-114.8-29.4-171.3-66.1-79.9000114.3F484 A492F484-Y488 AromaticContact CD2-CD2 3.54Å; F484-Y488 HydrophobicContact CD2-CD2 3.54Å; F484-Y488 HydrophobicContact CD2-CE2 4.04Å; F484-Y488 HydrophobicContact CD2-CG 4.32Å; F484-Y488 AromaticContact CE2-CD2 3.78Å; F484-Y488 HydrophobicContact CE2-CD2 3.78Å; F484-Y488 HydrophobicContact CE2-CE2 4.34Å; F484-Y488 HydrophobicContact CE2-CG 4.15Å; F484-Y488 HydrophobicContact CG-CD2 4.26Å; F484-Y488 WeakPolarHBondContact O-CB 3.18Å; F484-Y488 PolarHBondContact O-N 3.29Å; Y488-A492 VanDerWaalsContact O-CB 3.26Å; Y488-A492 WeakPolarHBondContact O-CB 3.36Å
489L68.7Low78.6Confident104 Ų10482.4 Ų82.455%0.54543%0.432SS..Iπ-helixtrans-99.5-27-176.4-65.6170.5000113.3F484 Y485F484-L489 HydrophobicContact CE1-CD1 4.46Å; Y485-L489 HydrophobicContact CD2-CB 4.13Å; Y485-L489 HydrophobicContact CD2-CD1 3.65Å; Y485-L489 HydrophobicContact CE2-CB 4.39Å; Y485-L489 HydrophobicContact CE2-CD1 4.29Å; Y485-L489 HydrophobicContact CG-CD1 4.49Å; Y485-L489 WeakPolarHBondContact O-CA 3.41Å; Y485-L489 WeakPolarHBondContact O-CB 3.37Å; Y485-L489 PolarHBondContact O-N 2.83Å
490M64.1Low77.5Confident121 Ų12188.5 Ų88.560%0.59647%0.465SS*.SBendtrans-100.7-17.8177.9-72.7-67-64.100113.8Y485Y485-M490 HydrophobicContact CD1-CG 4.15Å; Y485-M490 HydrophobicContact CE1-CG 3.61Å; Y485-M490 HydrophobicContact CE1-SD 4.28Å; Y485-M490 PolarHBondContact O-N 3.47Å; Y485-M490 VanDerWaalsContact O-N 3.16Å
491A53.6Low76.1Confident81 Ų8188.3 Ų88.367%0.66946%0.464SS*.  trans-94.5-14.4176.300000113.4Q487Q487-A491 WeakPolarHBondContact O-CB 3.48Å
492A37.7Very low74.6Confident130 Ų13088.1 Ų88.1100%1.07447%0.47SS*.  trans-88.60167.700000109.4Y488Y488-A492 VanDerWaalsContact O-CB 3.26Å; Y488-A492 WeakPolarHBondContact O-CB 3.36Å

Retrieved 492 of 492 residues in 255.8 ms (Link to these results)

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