A0A087XD30_POEFO Loading...

Serine protease 16

AlphaFold DB , UniProt , Accession A0A087XD30, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 453 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1G95.7Very high97.1Very high61 Ų6162.4 Ų62.463%0.62932%0.319SS*.  0-177.2000000110.5F22G1-F22 PolarHBondContact N-O 3.1Å; G1-F22 PolarHBondContact O-N 3.06Å
2R97.3Very high96.5Very high167 Ų16777.7 Ų77.763%0.6337%0.37SS*.EExtended strand (participates in β ladder)trans-138.2137.9174.7-80.5179.2178.6118.91.5109.3T19 Q20 F22R2-T19 HydrophobicContact CB-CG2 3.52Å; R2-T19 HydrophobicContact CG-CG2 3.68Å; R2-Q20 CarbonylContact C-O 3.36Å; R2-Q20 VanDerWaalsContact CA-O 3.32Å; R2-Q20 WeakPolarHBondContact CA-O 3.39Å; R2-F22 VanDerWaalsContact N-CE1 3.26Å
3V97.7Very high96.4Very high4 Ų485.2 Ų85.22%0.02440%0.404CS..EExtended strand (participates in β ladder)trans-119.9142.3174.763.30000109.3Q5 Q20 F22 F104 Y107V3-Q5 HydrophobicContact CG1-CG 4.23Å; V3-Q20 HydrophobicContact CG1-CB 3.82Å; V3-Q20 PolarHBondContact N-O 3.14Å; V3-Q20 PolarHBondContact O-N 3.32Å; V3-F22 HydrophobicContact CB-CD1 4.49Å; V3-F22 HydrophobicContact CB-CE1 4.26Å; V3-F22 HydrophobicContact CG1-CD1 4.42Å; V3-F104 HydrophobicContact CG1-CD2 3.98Å; V3-Y107 HydrophobicContact CB-CD1 4.1Å; V3-Y107 HydrophobicContact CB-CE1 4.29Å; V3-Y107 HydrophobicContact CB-CG 4.29Å; V3-Y107 HydrophobicContact CG2-CD1 3.87Å; V3-Y107 HydrophobicContact CG2-CD2 3.82Å; V3-Y107 HydrophobicContact CG2-CE1 4.39Å; V3-Y107 HydrophobicContact CG2-CE2 4.34Å; V3-Y107 HydrophobicContact CG2-CG 3.55Å
4H97.4Very high96.2Very high136 Ų13682 Ų8263%0.6339%0.391SS*.EExtended strand (participates in β ladder)trans-84.7122.6173.3-70.1-63.5000109.5
5Q98Very high96.1Very high0 Ų085.3 Ų85.30%042%0.418CS..EExtended strand (participates in β ladder)trans-112.3142.9-179.6-71.5-69.2-0.500110.3V3 L7 T17 F18 Q20 D100V3-Q5 HydrophobicContact CG1-CG 4.23Å; Q5-L7 PolarHBondContact O-N 3.07Å; Q5-T17 CarbonylContact O-C 3.53Å; Q5-T17 WeakPolarHBondContact O-CA 3.47Å; Q5-T17 WeakPolarHBondContact O-CB 3.47Å; Q5-F18 HydrophobicContact CB-CD1 3.68Å; Q5-F18 HydrophobicContact CB-CE1 3.22Å; Q5-F18 HydrophobicContact CB-CE2 4.4Å; Q5-F18 HydrophobicContact CB-CG 4.44Å; Q5-F18 HydrophobicContact CB-CZ 3.62Å; Q5-F18 HydrophobicContact CG-CE1 4.03Å; Q5-F18 HydrophobicContact CG-CZ 3.9Å; Q5-F18 PolarHBondContact N-O 3.15Å; Q5-F18 PolarHBondContact O-N 3.04Å; Q5-Q20 HydrophobicContact CG-CB 3.8Å; Q5-D100 PolarHBondContact NE2-O 3Å
6P97.4Very high96.1Very high46 Ų4688 Ų8830%0.29943%0.427SS..EExtended strand (participates in β ladder)trans-52.6135.3160.4-22.332.9000110.6R73P6-R73 PolarHBondContact O-NH2 3.16Å
7L96.7Very high96.1Very high10 Ų1087.4 Ų87.45%0.05243%0.43CS..SBendtrans-67.5-42.3174.4-177.362.2000110.4Q5 K16 F18 R73 D91Q5-L7 PolarHBondContact O-N 3.07Å; L7-K16 HydrophobicContact CB-CB 3.99Å; L7-K16 WeakPolarHBondContact CB-O 3.1Å; L7-K16 HydrophobicContact CD2-CB 3.83Å; L7-K16 HydrophobicContact CD2-CD 3.98Å; L7-K16 PolarHBondContact N-O 2.72Å; L7-F18 HydrophobicContact CD1-CD1 4.31Å; L7-R73 PolarHBondContact O-NH1 2.84Å; L7-D91 HydrophobicContact CD1-CB 4.14Å; L7-D91 HydrophobicContact CG-CB 4.32Å; L7-D91 WeakPolarHBondContact CG-OD2 3.31Å
8D97.5Very high96.1Very high27 Ų2782.9 Ų82.914%0.14441%0.408CS..  trans-126.5110.1177.9-174.4-11.1000110.5F10 N11 N14 Q96D8-F10 VanDerWaalsContact C-N 3.29Å; D8-F10 WeakPolarHBondContact OD1-CA 3.41Å; D8-F10 PolarHBondContact OD1-N 2.79Å; D8-N11 HydrophobicContact CB-CB 4.35Å; D8-N11 PolarHBondContact OD1-N 3.25Å; D8-N11 WeakPolarHBondContact OD2-CB 3.02Å; D8-N14 HydrophobicContact CB-CB 4.22Å; D8-Q96 PolarHBondContact OD1-NE2 2.74Å
9H97.9Very high96.2Very high43 Ų4380.9 Ų80.920%0.19940%0.401CS..SBendtrans-76.2-17.1178.6-66.6-83.3000113.3R73 Q96 A99 D100H9-R73 PolarHBondContact CD2-NH2 3.03Å; H9-R73 VanDerWaalsContact CD2-NH2 3.27Å; H9-R73 PolarHBondContact NE2-NH2 3.05Å; H9-Q96 PolarHBondContact CD2-OE1 2.92Å; H9-Q96 VanDerWaalsContact CD2-OE1 3.25Å; H9-A99 HydrophobicContact CB-CB 3.66Å; H9-A99 VanDerWaalsContact CD2-CB 3.47Å; H9-A99 WeakPolarHBondContact CD2-CB 3.44Å; H9-A99 VanDerWaalsContact CG-CB 3.41Å; H9-D100 IonicContact CD2-OD1 3.68Å; H9-D100 IonicContact CE1-OD1 3.68Å; H9-D100 PolarHBondContact NE2-N 2.92Å; H9-D100 IonicContact NE2-OD1 2.73Å; H9-D100 PolarHBondContact NE2-OD1 3.47Å
10F97.1Very high96.3Very high127 Ų12777.1 Ų77.156%0.55738%0.382SS*.SBendtrans-104.2-7.4-173.3-53.2-60.6000112.8D8 Q95 Q96 A99D8-F10 VanDerWaalsContact C-N 3.29Å; D8-F10 WeakPolarHBondContact OD1-CA 3.41Å; D8-F10 PolarHBondContact OD1-N 2.79Å; F10-Q95 HydrophobicContact CE2-CB 3.72Å; F10-Q95 HydrophobicContact CZ-CB 3.83Å; F10-Q96 VanDerWaalsContact CD2-CD 3.5Å; F10-Q96 HydrophobicContact CD2-CG 4.07Å; F10-Q96 HydrophobicContact CE2-CB 4.39Å; F10-Q96 HydrophobicContact CE2-CG 3.85Å; F10-A99 HydrophobicContact CZ-CB 4.3Å
11N95.8Very high96.4Very high65 Ų6575.2 Ų75.235%0.34837%0.37SS..  trans-12098.2170.4-175.3-0.3000112.3D8 Q13 N14D8-N11 HydrophobicContact CB-CB 4.35Å; D8-N11 PolarHBondContact OD1-N 3.25Å; D8-N11 WeakPolarHBondContact OD2-CB 3.02Å; N11-Q13 PolarHBondContact O-N 3.29Å; N11-Q13 VanDerWaalsContact O-N 3.1Å; N11-Q13 WeakPolarHBondContact OD1-CB 3.32Å; N11-Q13 PolarHBondContact OD1-N 2.73Å; N11-N14 HydrophobicContact CB-CB 4.3Å; N11-N14 WeakPolarHBondContact O-CB 3.23Å; N11-N14 PolarHBondContact O-N 3.48Å
12R90.1Very high96.6Very high246 Ų24672.8 Ų72.893%0.92834%0.343SS*.THydrogen-bonded Turntrans-64.4-16179.8-65.4-174.3178.8-177.8-0115N14R12-N14 VanDerWaalsContact C-N 3.31Å
13Q94.8Very high96.6Very high175 Ų17566.6 Ų66.682%0.81832%0.32SS*.THydrogen-bonded Turntrans-79.3-21175.6-61-177.8-11.700111.7N11 V15N11-Q13 PolarHBondContact O-N 3.29Å; N11-Q13 VanDerWaalsContact O-N 3.1Å; N11-Q13 WeakPolarHBondContact OD1-CB 3.32Å; N11-Q13 PolarHBondContact OD1-N 2.73Å; Q13-V15 PolarHBondContact O-N 3.27Å
14N93.1Very high96.7Very high41 Ų4168.6 Ų68.622%0.21933%0.332CS..  trans-81.1106.8175.2-171.1-4.8000109.7D8 N11 R12 K16D8-N14 HydrophobicContact CB-CB 4.22Å; N11-N14 HydrophobicContact CB-CB 4.3Å; N11-N14 WeakPolarHBondContact O-CB 3.23Å; N11-N14 PolarHBondContact O-N 3.48Å; R12-N14 VanDerWaalsContact C-N 3.31Å; N14-K16 VanDerWaalsContact OD1-CB 3.23Å; N14-K16 WeakPolarHBondContact OD1-CB 3.14Å; N14-K16 VanDerWaalsContact OD1-CG 3.32Å; N14-K16 WeakPolarHBondContact OD1-CG 3.38Å; N14-K16 PolarHBondContact OD1-N 2.77Å
15V94.6Very high96.7Very high132 Ų13262.9 Ų62.980%0.831%0.307SS*.  trans-92.74.7178.9-61.20000113.2Q13Q13-V15 PolarHBondContact O-N 3.27Å
16K95.8Very high96.7Very high128 Ų12866.8 Ų66.856%0.55733%0.325SS*.  trans-68.4151.4178.1-64.5178.9179.5-178.70110.4L7 N14L7-K16 HydrophobicContact CB-CB 3.99Å; L7-K16 WeakPolarHBondContact CB-O 3.1Å; L7-K16 HydrophobicContact CD2-CB 3.83Å; L7-K16 HydrophobicContact CD2-CD 3.98Å; L7-K16 PolarHBondContact N-O 2.72Å; N14-K16 VanDerWaalsContact OD1-CB 3.23Å; N14-K16 WeakPolarHBondContact OD1-CB 3.14Å; N14-K16 VanDerWaalsContact OD1-CG 3.32Å; N14-K16 WeakPolarHBondContact OD1-CG 3.38Å; N14-K16 PolarHBondContact OD1-N 2.77Å
17T96.6Very high96.7Very high78 Ų7868.4 Ų68.448%0.47934%0.342SS..EExtended strand (participates in β ladder)trans-130.1164.5178.357.70000110.7Q5 N80Q5-T17 CarbonylContact O-C 3.53Å; Q5-T17 WeakPolarHBondContact O-CA 3.47Å; Q5-T17 WeakPolarHBondContact O-CB 3.47Å; T17-N80 PolarHBondContact O-ND2 3.33Å
18F97.2Very high96.6Very high7 Ų771.9 Ų71.93%0.03136%0.355CS..EExtended strand (participates in β ladder)trans-132.2167.3164.977.9-76.5000109.7Q5 L7 Q20 R73 N80Q5-F18 HydrophobicContact CB-CD1 3.68Å; Q5-F18 HydrophobicContact CB-CE1 3.22Å; Q5-F18 HydrophobicContact CB-CE2 4.4Å; Q5-F18 HydrophobicContact CB-CG 4.44Å; Q5-F18 HydrophobicContact CB-CZ 3.62Å; Q5-F18 HydrophobicContact CG-CE1 4.03Å; Q5-F18 HydrophobicContact CG-CZ 3.9Å; Q5-F18 PolarHBondContact N-O 3.15Å; Q5-F18 PolarHBondContact O-N 3.04Å; L7-F18 HydrophobicContact CD1-CD1 4.31Å; F18-Q20 HydrophobicContact CE2-CB 3.8Å; F18-Q20 HydrophobicContact CE2-CG 4.29Å; F18-Q20 HydrophobicContact CZ-CB 4.26Å; F18-R73 HydrophobicContact CE1-CB 4.4Å; F18-R73 HydrophobicContact CE2-CB 3.87Å; F18-R73 HydrophobicContact CZ-CB 3.61Å; F18-N80 VanDerWaalsContact CA-OD1 3.28Å; F18-N80 WeakPolarHBondContact CA-OD1 3.41Å; F18-N80 WeakPolarHBondContact CB-OD1 3.49Å
19T97.6Very high96.7Very high45 Ų4571.5 Ų71.528%0.27635%0.352SS..EExtended strand (participates in β ladder)trans-104.9120.3177.8-53.80000109.8R2R2-T19 HydrophobicContact CB-CG2 3.52Å; R2-T19 HydrophobicContact CG-CG2 3.68Å
20Q98.4Very high96.6Very high4 Ų474.3 Ų74.32%0.01937%0.365CS..EExtended strand (participates in β ladder)trans-100.2131.3179.9-172.2-177.332.800110.2R2 V3 Q5 F18 V70 E71R2-Q20 CarbonylContact C-O 3.36Å; R2-Q20 VanDerWaalsContact CA-O 3.32Å; R2-Q20 WeakPolarHBondContact CA-O 3.39Å; V3-Q20 HydrophobicContact CG1-CB 3.82Å; V3-Q20 PolarHBondContact N-O 3.14Å; V3-Q20 PolarHBondContact O-N 3.32Å; Q5-Q20 HydrophobicContact CG-CB 3.8Å; F18-Q20 HydrophobicContact CE2-CB 3.8Å; F18-Q20 HydrophobicContact CE2-CG 4.29Å; F18-Q20 HydrophobicContact CZ-CB 4.26Å; Q20-V70 HydrophobicContact CG-CG2 4.12Å; Q20-E71 VanDerWaalsContact CG-O 3.31Å; Q20-E71 WeakPolarHBondContact CG-O 3.27Å; Q20-E71 PolarHBondContact NE2-O 3.39Å
21R98.4Very high96.4Very high37 Ų3775.2 Ų75.214%0.1436%0.364CS..EExtended strand (participates in β ladder)trans-82.2145178.7-177167.367.1152.315.6110.6I46 E71 D77 S78R21-I46 PolarHBondContact NH2-O 3.4Å; R21-E71 HydrophobicContact CB-CB 4.11Å; R21-E71 WeakPolarHBondContact CB-OE2 3.37Å; R21-E71 IonicContact CZ-OE1 3.77Å; R21-E71 VanDerWaalsContact CZ-OE1 3.25Å; R21-E71 IonicContact CZ-OE2 3.34Å; R21-E71 IonicContact NE-OE1 3.59Å; R21-E71 PolarHBondContact NE-OE1 2.98Å; R21-E71 VanDerWaalsContact NE-OE1 3.13Å; R21-E71 IonicContact NE-OE2 2.93Å; R21-E71 PolarHBondContact NE-OE2 2.79Å; R21-E71 VanDerWaalsContact NE-OE2 3.1Å; R21-E71 IonicContact NH2-OE1 3.36Å; R21-E71 PolarHBondContact NH2-OE1 3.09Å; R21-E71 IonicContact NH2-OE2 2.83Å; R21-E71 VanDerWaalsContact O-CB 3.28Å; R21-E71 WeakPolarHBondContact O-CB 3.5Å; R21-E71 PolarHBondContact O-N 3.32Å; R21-D77 IonicContact CZ-OD2 3.8Å; R21-D77 IonicContact NE-OD2 2.76Å; R21-D77 IonicContact NH1-OD2 2.68Å; R21-D77 PolarHBondContact NH1-OD2 3.44Å; R21-S78 PolarHBondContact N-OG 3.4Å
22F98.7Very high96.3Very high10 Ų1075.4 Ų75.44%0.04437%0.37CS..EExtended strand (participates in β ladder)trans-149.1158.1170.668.5-90000111.4G1 R2 V3 V24 A69 V70 F104 Y107 I108G1-F22 PolarHBondContact N-O 3.1Å; G1-F22 PolarHBondContact O-N 3.06Å; R2-F22 VanDerWaalsContact N-CE1 3.26Å; V3-F22 HydrophobicContact CB-CD1 4.49Å; V3-F22 HydrophobicContact CB-CE1 4.26Å; V3-F22 HydrophobicContact CG1-CD1 4.42Å; F22-V24 HydrophobicContact CD2-CG2 3.6Å; F22-V24 HydrophobicContact CE2-CG2 3.4Å; F22-V24 VanDerWaalsContact CE2-CG2 3.4Å; F22-A69 CarbonylContact C-O 3.57Å; F22-A69 WeakPolarHBondContact CA-O 3.29Å; F22-A69 WeakPolarHBondContact CB-O 3.45Å; F22-V70 HydrophobicContact CB-CB 4.36Å; F22-V70 HydrophobicContact CB-CG2 4.36Å; F22-F104 HydrophobicContact CB-CE2 3.68Å; F22-F104 HydrophobicContact CB-CZ 3.76Å; F22-F104 HydrophobicContact CD1-CD2 4.45Å; F22-F104 AromaticContact CD1-CE2 3.63Å; F22-F104 HydrophobicContact CD1-CE2 3.63Å; F22-F104 HydrophobicContact CD1-CZ 4.45Å; F22-F104 AromaticContact CD2-CE2 3.86Å; F22-F104 HydrophobicContact CD2-CE2 3.86Å; F22-F104 AromaticContact CD2-CZ 3.95Å; F22-F104 HydrophobicContact CD2-CZ 3.95Å; F22-F104 HydrophobicContact CE1-CE2 4.15Å; F22-F104 HydrophobicContact CE2-CE2 4.37Å; F22-F104 AromaticContact CG-CE2 3.46Å; F22-F104 HydrophobicContact CG-CE2 3.46Å; F22-F104 VanDerWaalsContact CG-CE2 3.46Å; F22-F104 AromaticContact CG-CZ 3.83Å; F22-F104 HydrophobicContact CG-CZ 3.83Å; F22-Y107 AromaticContact CE1-CE1 3.86Å; F22-Y107 HydrophobicContact CE1-CE1 3.86Å; F22-Y107 AromaticContact CZ-CE1 3.72Å; F22-Y107 HydrophobicContact CZ-CE1 3.72Å; F22-I108 HydrophobicContact CD2-CD1 4.36Å; F22-I108 HydrophobicContact CE2-CD1 3.9Å; F22-I108 HydrophobicContact CZ-CD1 4.27Å
23F98.7Very high96.3Very high37 Ų3767.4 Ų67.416%0.16235%0.345CS..EExtended strand (participates in β ladder)trans-113.4152.9169.5-63.7-62.9000110.9I46 Y47 N48 V51 L68 A69F23-I46 HydrophobicContact CD2-CD1 3.68Å; F23-I46 HydrophobicContact CD2-CG1 4.02Å; F23-I46 HydrophobicContact CE2-CB 4.45Å; F23-I46 HydrophobicContact CE2-CD1 3.91Å; F23-I46 HydrophobicContact CE2-CG1 3.8Å; F23-Y47 VanDerWaalsContact CD2-O 3.29Å; F23-Y47 WeakPolarHBondContact CD2-O 3.3Å; F23-N48 WeakPolarHBondContact CD1-OD1 3.3Å; F23-N48 WeakPolarHBondContact CE1-OD1 3.27Å; F23-N48 WeakPolarHBondContact CZ-OD1 3.22Å; F23-V51 HydrophobicContact CB-CG1 3.98Å; F23-V51 HydrophobicContact CB-CG2 3.84Å; F23-L68 WeakPolarHBondContact O-CA 3.49Å; F23-A69 HydrophobicContact CB-CB 4.45Å; F23-A69 PolarHBondContact N-O 3.47Å; F23-A69 PolarHBondContact O-N 2.95Å
24V98.5Very high96.4Very high46 Ų4659.3 Ų59.328%0.27931%0.309SS..EExtended strand (participates in β ladder)trans-133.7136.7176.8-174.80000107.9F22 E26 L66 L67 L68 F112F22-V24 HydrophobicContact CD2-CG2 3.6Å; F22-V24 HydrophobicContact CE2-CG2 3.4Å; F22-V24 VanDerWaalsContact CE2-CG2 3.4Å; V24-E26 HydrophobicContact CG1-CG 3.79Å; V24-L66 HydrophobicContact CG1-CD1 3.81Å; V24-L67 CarbonylContact C-O 3.55Å; V24-L67 WeakPolarHBondContact CA-O 3.45Å; V24-L68 HydrophobicContact CB-CD2 4.23Å; V24-L68 HydrophobicContact CG1-CD2 3.93Å; V24-L68 HydrophobicContact CG2-CD2 3.72Å; V24-F112 HydrophobicContact CG1-CE1 4.35Å; V24-F112 HydrophobicContact CG1-CZ 3.85Å; V24-F112 HydrophobicContact CG2-CZ 4.37Å
25N98.3Very high96.7Very high17 Ų1758.2 Ų58.29%0.09130%0.304CS..EExtended strand (participates in β ladder)trans-127.8115.1166.8179.47.3000109.6A27 V51 L67N25-A27 WeakPolarHBondContact OD1-CB 3.35Å; N25-A27 PolarHBondContact OD1-N 3.06Å; N25-V51 HydrophobicContact CB-CB 3.85Å; N25-V51 HydrophobicContact CB-CG2 3.95Å; N25-V51 WeakPolarHBondContact CB-O 3.42Å; N25-V51 PolarHBondContact ND2-O 2.74Å; N25-L67 HydrophobicContact CB-CB 3.99Å; N25-L67 HydrophobicContact CB-CD1 4.47Å; N25-L67 PolarHBondContact N-O 3.02Å; N25-L67 PolarHBondContact O-N 3.21Å; N25-L67 VanDerWaalsContact O-N 3.07Å
26E97.4Very high96.9Very high82 Ų8251.9 Ų51.938%0.38327%0.265SS..  trans-99.2-2.4-178.1-53.9-175.9-130.800113.1V24 Y28 W29 R31 L66 F112V24-E26 HydrophobicContact CG1-CG 3.79Å; E26-Y28 PolarHBondContact O-N 3.22Å; E26-W29 PolarHBondContact O-N 3.41Å; E26-R31 IonicContact OE2-CZ 3.49Å; E26-R31 IonicContact OE2-NE 3.68Å; E26-R31 PolarHBondContact OE2-NE 3.13Å; E26-R31 IonicContact OE2-NH2 3.33Å; E26-R31 PolarHBondContact OE2-NH2 3.16Å; E26-L66 HydrophobicContact CB-CD1 4.48Å; E26-L66 HydrophobicContact CG-CD1 3.88Å; E26-F112 HydrophobicContact CG-CE1 4.18Å
27A97.1Very high97Very high80 Ų8045.8 Ų45.866%0.66124%0.239SC*.THydrogen-bonded Turntrans-58.4-25.1-167.700000113.9N25N25-A27 WeakPolarHBondContact OD1-CB 3.35Å; N25-A27 PolarHBondContact OD1-N 3.06Å
28Y95.9Very high97.1Very high83 Ų8342.1 Ų42.133%0.32522%0.216SC..THydrogen-bonded Turntrans-107.8-6.9-179.3-48.4-52.1000113.6E26 Q30 V57 K61 R64 L67E26-Y28 PolarHBondContact O-N 3.22Å; Y28-Q30 PolarHBondContact O-N 3.33Å; Y28-V57 HydrophobicContact CE2-CG1 4.16Å; Y28-K61 HydrophobicContact CD1-CB 4.21Å; Y28-K61 HydrophobicContact CD1-CG 3.88Å; Y28-K61 HydrophobicContact CD2-CB 4.03Å; Y28-K61 HydrophobicContact CE1-CB 4.41Å; Y28-K61 HydrophobicContact CE1-CD 4.17Å; Y28-K61 HydrophobicContact CE1-CG 4Å; Y28-K61 HydrophobicContact CE2-CB 4.22Å; Y28-K61 HydrophobicContact CG-CB 4.03Å; Y28-K61 HydrophobicContact CG-CG 4.2Å; Y28-R64 CarbonylContact O-C 3.57Å; Y28-R64 VanDerWaalsContact O-C 3.28Å; Y28-R64 WeakPolarHBondContact O-CA 3.38Å; Y28-R64 VanDerWaalsContact O-CB 3.31Å; Y28-R64 WeakPolarHBondContact O-CB 3.4Å; Y28-L67 HydrophobicContact CD2-CD1 4.15Å; Y28-L67 HydrophobicContact CE2-CD1 4.39Å
29W97.8Very high97.2Very high19 Ų1943 Ų437%0.07222%0.22CC..  trans-73.1120.3-167-17737.5000112.2E26 R31 G34 R64 L66 F112 L114E26-W29 PolarHBondContact O-N 3.41Å; W29-R31 HydrophobicContact CD2-CG 3.7Å; W29-R31 HydrophobicContact CE3-CG 3.32Å; W29-R31 HydrophobicContact CG-CG 4.46Å; W29-R31 HydrophobicContact CH2-CG 3.91Å; W29-R31 HydrophobicContact CZ2-CG 4.24Å; W29-R31 HydrophobicContact CZ3-CG 3.46Å; W29-R31 VanDerWaalsContact CZ3-CG 3.46Å; W29-R31 PolarHBondContact O-N 3.19Å; W29-G34 PolarHBondContact NE1-O 2.91Å; W29-R64 WeakPolarHBondContact CA-O 3.46Å; W29-L66 HydrophobicContact CB-CB 4.2Å; W29-L66 HydrophobicContact CD2-CB 3.87Å; W29-L66 HydrophobicContact CD2-CD1 4.24Å; W29-L66 HydrophobicContact CD2-CG 4.44Å; W29-L66 HydrophobicContact CE3-CB 4.46Å; W29-L66 HydrophobicContact CE3-CD1 4.02Å; W29-L66 HydrophobicContact CE3-CD2 4.49Å; W29-L66 HydrophobicContact CG-CB 3.69Å; W29-L66 HydrophobicContact CG-CD1 4.45Å; W29-F112 HydrophobicContact CH2-CB 4.08Å; W29-F112 HydrophobicContact CH2-CD1 4.32Å; W29-F112 HydrophobicContact CZ3-CB 4.35Å; W29-F112 AromaticContact CZ3-CD1 3.74Å; W29-F112 HydrophobicContact CZ3-CD1 3.74Å; W29-F112 HydrophobicContact CZ3-CG 4.49Å; W29-L114 HydrophobicContact CH2-CD2 3.63Å; W29-L114 HydrophobicContact CZ2-CD2 3.39Å
30Q96.8Very high97.3Very high101 Ų10141 Ų4147%0.47221%0.208SC..  trans-76.587.5171.2-177171.3-13.300110.2Y28 D33 G34 R64Y28-Q30 PolarHBondContact O-N 3.33Å; Q30-D33 PolarHBondContact O-N 2.89Å; Q30-D33 VanDerWaalsContact O-N 3.09Å; Q30-G34 PolarHBondContact O-N 2.92Å; Q30-R64 HydrophobicContact CB-CB 3.69Å; Q30-R64 HydrophobicContact CB-CG 4.5Å; Q30-R64 PolarHBondContact N-O 3.13Å
31R93.9Very high97.3Very high146 Ų14641 Ų4155%0.55121%0.208SC*.THydrogen-bonded Turntrans-61.7141.5175.2-75173.4167.9-94.411.8111.7E26 W29E26-R31 IonicContact OE2-CZ 3.49Å; E26-R31 IonicContact OE2-NE 3.68Å; E26-R31 PolarHBondContact OE2-NE 3.13Å; E26-R31 IonicContact OE2-NH2 3.33Å; E26-R31 PolarHBondContact OE2-NH2 3.16Å; W29-R31 HydrophobicContact CD2-CG 3.7Å; W29-R31 HydrophobicContact CE3-CG 3.32Å; W29-R31 HydrophobicContact CG-CG 4.46Å; W29-R31 HydrophobicContact CH2-CG 3.91Å; W29-R31 HydrophobicContact CZ2-CG 4.24Å; W29-R31 HydrophobicContact CZ3-CG 3.46Å; W29-R31 VanDerWaalsContact CZ3-CG 3.46Å; W29-R31 PolarHBondContact O-N 3.19Å
32P92.3Very high97.2Very high70 Ų7039.7 Ų39.746%0.45521%0.207SC..THydrogen-bonded Turncis-91.8-2.5-735.2-31.4000113.9N118P32-N118 PolarHBondContact O-ND2 3.12Å
33D91.1Very high97.1Very high78 Ų7842.1 Ų42.142%0.41722%0.218SC..THydrogen-bonded Turntrans-105.7-5.7-160.2-58.7-47.6000115.2Q30 R117Q30-D33 PolarHBondContact O-N 2.89Å; Q30-D33 VanDerWaalsContact O-N 3.09Å; D33-R117 IonicContact OD1-CZ 3.67Å; D33-R117 IonicContact OD1-NE 3.83Å; D33-R117 PolarHBondContact OD1-NE 3.25Å; D33-R117 IonicContact OD1-NH2 2.71Å; D33-R117 PolarHBondContact OD1-NH2 2.98Å
34G96.8Very high96.9Very high5 Ų541.3 Ų41.35%0.05222%0.22CC..  trans-57.8148.8179.300000112.2W29 Q30 N118W29-G34 PolarHBondContact NE1-O 2.91Å; Q30-G34 PolarHBondContact O-N 2.92Å; G34-N118 PolarHBondContact O-ND2 2.93Å
35P98.4Very high96.7Very high17 Ų1741.2 Ų41.211%0.1122%0.221CC..  trans-64.3171.1178.528.2-33.2000111.7F37 H63 A65 L66 T119 L440P35-F37 HydrophobicContact CB-CE1 4.34Å; P35-F37 HydrophobicContact CG-CE1 4.37Å; P35-H63 WeakPolarHBondContact CD-O 3.15Å; P35-H63 HydrophobicContact CG-CB 4.29Å; P35-A65 HydrophobicContact CG-CB 3.85Å; P35-A65 CarbonylContact O-C 3.6Å; P35-A65 WeakPolarHBondContact O-CA 3.32Å; P35-A65 WeakPolarHBondContact O-CB 3.35Å; P35-L66 PolarHBondContact O-N 3.16Å; P35-T119 CarbonylContact C-O 3.59Å; P35-T119 VanDerWaalsContact CA-O 3.29Å; P35-T119 WeakPolarHBondContact CA-O 3.47Å; P35-T119 WeakPolarHBondContact CB-O 3.36Å; P35-L440 HydrophobicContact CB-CD2 3.69Å; P35-L440 HydrophobicContact CG-CD1 4.22Å; P35-L440 HydrophobicContact CG-CD2 4.18Å
36V98.8Very high96.6Very high0 Ų040.6 Ų40.60%022%0.217CC..EExtended strand (participates in β ladder)trans-120123.4177.9-174.50000109.2L66 L68 L114 N118 T119 W120 I121V36-L66 WeakPolarHBondContact CA-O 3.34Å; V36-L66 HydrophobicContact CG1-CB 4.47Å; V36-L66 HydrophobicContact CG1-CD2 4.45Å; V36-L66 HydrophobicContact CG2-CB 4.33Å; V36-L66 HydrophobicContact CG2-CD2 4.38Å; V36-L68 HydrophobicContact CG1-CD1 3.37Å; V36-L68 HydrophobicContact CG1-CG 4.11Å; V36-L114 HydrophobicContact CG2-CD1 3.77Å; V36-N118 HydrophobicContact CG2-CB 4.21Å; V36-T119 PolarHBondContact N-O 2.87Å; V36-W120 HydrophobicContact CB-CD2 3.6Å; V36-W120 HydrophobicContact CB-CE3 3.87Å; V36-W120 HydrophobicContact CB-CG 3.96Å; V36-W120 HydrophobicContact CB-CZ2 4.35Å; V36-W120 HydrophobicContact CB-CZ3 4.34Å; V36-W120 HydrophobicContact CG1-CD2 3.71Å; V36-W120 HydrophobicContact CG1-CE3 3.46Å; V36-W120 VanDerWaalsContact CG1-CE3 3.46Å; V36-W120 HydrophobicContact CG1-CH2 3.79Å; V36-W120 HydrophobicContact CG1-CZ2 4.02Å; V36-W120 HydrophobicContact CG1-CZ3 3.5Å; V36-W120 HydrophobicContact CG2-CD2 4.09Å; V36-W120 HydrophobicContact CG2-CG 4.42Å; V36-W120 HydrophobicContact CG2-CZ2 4.18Å; V36-W120 CarbonylContact O-C 3.47Å; V36-W120 WeakPolarHBondContact O-CA 3.28Å; V36-I121 PolarHBondContact O-N 3.24Å
37F98.9Very high96.5Very high0 Ų042.5 Ų42.50%022%0.222CC..EExtended strand (participates in β ladder)trans-106.2116.3176.3-77.716.1000108.6P35 H56 M59 A60 H63 A65 L66 L67 L68 I121 F123 V436 L440P35-F37 HydrophobicContact CB-CE1 4.34Å; P35-F37 HydrophobicContact CG-CE1 4.37Å; F37-H56 WeakPolarHBondContact CD2-O 3.27Å; F37-M59 HydrophobicContact CE2-CB 3.71Å; F37-A60 HydrophobicContact CD2-CB 3.65Å; F37-A60 HydrophobicContact CE2-CB 4.17Å; F37-A60 HydrophobicContact CG-CB 4.31Å; F37-H63 HydrophobicContact CZ-CB 4.35Å; F37-A65 HydrophobicContact CB-CB 4.34Å; F37-A65 HydrophobicContact CD1-CB 3.83Å; F37-A65 HydrophobicContact CD2-CB 4.24Å; F37-A65 HydrophobicContact CE1-CB 4.16Å; F37-A65 HydrophobicContact CG-CB 3.86Å; F37-A65 HydrophobicContact CZ-CB 4.49Å; F37-L66 PolarHBondContact N-O 3.14Å; F37-L67 HydrophobicContact CB-CD2 3.92Å; F37-L68 PolarHBondContact O-N 3.3Å; F37-I121 WeakPolarHBondContact CA-O 3.12Å; F37-I121 HydrophobicContact CD1-CB 4.06Å; F37-I121 HydrophobicContact CD1-CG1 4.36Å; F37-I121 HydrophobicContact CE1-CB 4.11Å; F37-I121 HydrophobicContact CE1-CG1 4Å; F37-F123 HydrophobicContact CB-CD2 4.26Å; F37-F123 HydrophobicContact CB-CE2 3.7Å; F37-F123 AromaticContact CD1-CE2 3.97Å; F37-F123 HydrophobicContact CD1-CE2 3.97Å; F37-F123 HydrophobicContact CD1-CZ 4.38Å; F37-F123 AromaticContact CD2-CE2 3.55Å; F37-F123 HydrophobicContact CD2-CE2 3.55Å; F37-F123 AromaticContact CD2-CZ 3.66Å; F37-F123 HydrophobicContact CD2-CZ 3.66Å; F37-F123 HydrophobicContact CE1-CE2 4.5Å; F37-F123 HydrophobicContact CE1-CZ 4.49Å; F37-F123 HydrophobicContact CE2-CE2 4.14Å; F37-F123 AromaticContact CE2-CZ 3.79Å; F37-F123 HydrophobicContact CE2-CZ 3.79Å; F37-F123 HydrophobicContact CG-CD2 4.47Å; F37-F123 AromaticContact CG-CE2 3.47Å; F37-F123 HydrophobicContact CG-CE2 3.47Å; F37-F123 VanDerWaalsContact CG-CE2 3.47Å; F37-F123 AromaticContact CG-CZ 4Å; F37-F123 HydrophobicContact CG-CZ 4Å; F37-F123 HydrophobicContact CZ-CZ 4.22Å; F37-V436 HydrophobicContact CE1-CG1 4.32Å; F37-V436 HydrophobicContact CE2-CG1 4.42Å; F37-V436 HydrophobicContact CZ-CG1 3.68Å; F37-L440 HydrophobicContact CE1-CD1 4.21Å; F37-L440 HydrophobicContact CE1-CD2 4.5Å; F37-L440 HydrophobicContact CZ-CD1 4.19Å
38L98.9Very high96.5Very high0 Ų043.4 Ų43.40%022%0.215CC..EExtended strand (participates in β ladder)trans-108.1108.2-176.217661.7000110.3I40 L68 V70 F104 W120 I121 S122 F123 F135L38-I40 HydrophobicContact CD2-CG1 4.27Å; L38-I40 HydrophobicContact CG-CG1 4.12Å; L38-L68 HydrophobicContact CD1-CB 3.82Å; L38-L68 HydrophobicContact CD1-CD1 4.48Å; L38-V70 HydrophobicContact CD1-CB 4.45Å; L38-V70 HydrophobicContact CD1-CG1 3.88Å; L38-F104 HydrophobicContact CD1-CD1 4.21Å; L38-F104 HydrophobicContact CD1-CE1 3.7Å; L38-W120 HydrophobicContact CB-CE3 4.32Å; L38-W120 HydrophobicContact CB-CZ3 4.4Å; L38-W120 HydrophobicContact CD2-CZ3 4.33Å; L38-I121 PolarHBondContact N-O 2.89Å; L38-S122 CarbonylContact O-C 3.35Å; L38-S122 VanDerWaalsContact O-CA 3.27Å; L38-S122 WeakPolarHBondContact O-CA 3.36Å; L38-F123 PolarHBondContact O-N 3.42Å; L38-F135 HydrophobicContact CD2-CE1 4.27Å
39F98.8Very high96.4Very high27 Ų2745 Ų4512%0.11822%0.224CC..EExtended strand (participates in β ladder)trans-79.8121.9165.3-173-85000109.7D50 H56 L68 A69 V70 M414F39-D50 HydrophobicContact CD1-CB 4.08Å; F39-D50 HydrophobicContact CE1-CB 4.23Å; F39-H56 AromaticContact CD2-CD2 3.92Å; F39-H56 AromaticContact CD2-CE1 3.82Å; F39-H56 AromaticContact CD2-NE2 3.55Å; F39-L68 PolarHBondContact N-O 2.96Å; F39-A69 HydrophobicContact CB-CB 4.1Å; F39-A69 HydrophobicContact CD1-CB 4.21Å; F39-A69 VanDerWaalsContact O-CA 3.28Å; F39-A69 WeakPolarHBondContact O-CA 3.46Å; F39-V70 PolarHBondContact O-N 3.4Å; F39-V70 VanDerWaalsContact O-N 3.07Å; F39-M414 HydrophobicContact CD2-CE 4.11Å; F39-M414 HydrophobicContact CE2-CE 3.58Å
40I98.8Very high96.3Very high3 Ų344.7 Ų44.72%0.01522%0.224CC..EExtended strand (participates in β ladder)trans-93.7126.5179.2-64.6165.3000108.6L38 L101 F123 S128 L131 F135L38-I40 HydrophobicContact CD2-CG1 4.27Å; L38-I40 HydrophobicContact CG-CG1 4.12Å; I40-L101 HydrophobicContact CD1-CD1 3.65Å; I40-L101 HydrophobicContact CG1-CD1 4.07Å; I40-L101 HydrophobicContact CG1-CD2 4.06Å; I40-L101 HydrophobicContact CG2-CD1 4.18Å; I40-L101 HydrophobicContact CG2-CD2 4.25Å; I40-F123 PolarHBondContact N-O 2.86Å; I40-S128 VanDerWaalsContact O-CB 3.24Å; I40-S128 WeakPolarHBondContact O-CB 3.25Å; I40-S128 PolarHBondContact O-OG 3.21Å; I40-L131 HydrophobicContact CG2-CB 3.89Å; I40-L131 HydrophobicContact CG2-CD1 4.03Å; I40-F135 HydrophobicContact CD1-CB 4.4Å; I40-F135 HydrophobicContact CD1-CD1 4.38Å
41G98.2Very high96.4Very high2 Ų240.1 Ų40.12%0.02120%0.203CC..PPolyproline II helixtrans-71.4145.2173.600000112.3V70G41-V70 WeakPolarHBondContact CA-O 3.28Å; G41-V70 PolarHBondContact N-O 3.18Å
42G96.8Very high96.5Very high11 Ų1138.2 Ų38.211%0.11320%0.203CC..  trans-105-138.7176.700000112.5G44 H72G42-G44 PolarHBondContact O-N 2.81Å; G42-H72 WeakPolarHBondContact O-CB 3.32Å
43E96.1Very high96.7Very high60 Ų6036.8 Ų36.828%0.2820%0.198SC..SBendtrans-74.736.1-176.369-83-154.100114.1Y75 Y127 W311E43-Y75 VanDerWaalsContact C-CE1 3.41Å; E43-Y75 VanDerWaalsContact CA-CE1 3.43Å; E43-Y75 HydrophobicContact CB-CE1 3.87Å; E43-Y75 WeakPolarHBondContact O-CD1 3.3Å; E43-Y75 WeakPolarHBondContact O-CE1 3.28Å; E43-Y127 HydrophobicContact CB-CD1 4.29Å; E43-Y127 WeakPolarHBondContact OE2-CB 3.43Å; E43-W311 HydrophobicContact CB-CD2 4.06Å; E43-W311 HydrophobicContact CB-CE3 3.6Å; E43-W311 HydrophobicContact CB-CG 4.47Å; E43-W311 HydrophobicContact CB-CZ3 4.15Å; E43-W311 HydrophobicContact CG-CD2 4.22Å; E43-W311 HydrophobicContact CG-CE3 4.15Å
44G94.7Very high97Very high20 Ų2033.4 Ų33.421%0.20618%0.181CC..SBendtrans-164.9170.2-176.400000113.7G42G42-G44 PolarHBondContact O-N 2.81Å
45P95.1Very high97Very high45 Ų4533.4 Ų33.429%0.29218%0.179SC..  trans-62.9140.1171.227-33.3000110.8Y47 E71P45-Y47 HydrophobicContact CB-CE2 4.21Å; P45-Y47 HydrophobicContact CG-CE2 3.78Å; P45-Y47 VanDerWaalsContact CG-OH 3.23Å; P45-Y47 WeakPolarHBondContact CG-OH 3.31Å; P45-Y47 WeakPolarHBondContact O-CD2 3.33Å; P45-Y47 VanDerWaalsContact O-CE2 3.31Å; P45-Y47 WeakPolarHBondContact O-CE2 2.97Å; P45-E71 WeakPolarHBondContact CA-OE1 3.34Å
46I96.4Very high97Very high3 Ų333 Ų332%0.01518%0.176CC..  trans-81.7161.2162.462.2167.7000110.3R21 F23 D50 A69 E71R21-I46 PolarHBondContact NH2-O 3.4Å; F23-I46 HydrophobicContact CD2-CD1 3.68Å; F23-I46 HydrophobicContact CD2-CG1 4.02Å; F23-I46 HydrophobicContact CE2-CB 4.45Å; F23-I46 HydrophobicContact CE2-CD1 3.91Å; F23-I46 HydrophobicContact CE2-CG1 3.8Å; I46-D50 WeakPolarHBondContact CA-OD2 3.17Å; I46-D50 WeakPolarHBondContact CB-OD2 3.35Å; I46-A69 HydrophobicContact CD1-CB 4.39Å; I46-E71 HydrophobicContact CD1-CB 3.74Å; I46-E71 HydrophobicContact CG1-CB 3.71Å; I46-E71 HydrophobicContact CG1-CG 4.09Å; I46-E71 WeakPolarHBondContact CG1-OE1 3.35Å; I46-E71 HydrophobicContact CG2-CB 4.39Å; I46-E71 PolarHBondContact N-OE1 3.34Å
47Y95.8Very high97Very high123 Ų12333.2 Ų33.248%0.48218%0.177SC..  trans-136.7167.1179.6-62-85.1000111.1F23 P45 F49 D50F23-Y47 VanDerWaalsContact CD2-O 3.29Å; F23-Y47 WeakPolarHBondContact CD2-O 3.3Å; P45-Y47 HydrophobicContact CB-CE2 4.21Å; P45-Y47 HydrophobicContact CG-CE2 3.78Å; P45-Y47 VanDerWaalsContact CG-OH 3.23Å; P45-Y47 WeakPolarHBondContact CG-OH 3.31Å; P45-Y47 WeakPolarHBondContact O-CD2 3.33Å; P45-Y47 VanDerWaalsContact O-CE2 3.31Å; P45-Y47 WeakPolarHBondContact O-CE2 2.97Å; Y47-F49 VanDerWaalsContact CB-CE1 3.47Å; Y47-F49 HydrophobicContact CD2-CD1 4.18Å; Y47-F49 AromaticContact CD2-CE1 3.39Å; Y47-F49 HydrophobicContact CD2-CE1 3.39Å; Y47-F49 HydrophobicContact CD2-CZ 4.12Å; Y47-F49 HydrophobicContact CE2-CE1 4.32Å; Y47-F49 HydrophobicContact CG-CD1 4.02Å; Y47-F49 AromaticContact CG-CE1 3.69Å; Y47-F49 HydrophobicContact CG-CE1 3.69Å; Y47-F49 PolarHBondContact O-N 2.69Å; Y47-F49 VanDerWaalsContact O-N 3.12Å; Y47-D50 PolarHBondContact N-OD2 3.14Å; Y47-D50 WeakPolarHBondContact O-CB 3.44Å; Y47-D50 PolarHBondContact O-N 3.42Å; Y47-D50 VanDerWaalsContact O-N 3.09Å
48N95.4Very high96.9Very high98 Ų9836 Ų3652%0.52419%0.192SC..G310 helixtrans-56-31.5175.9-71-23.8000112.1F23 D50 V51 L52F23-N48 WeakPolarHBondContact CD1-OD1 3.3Å; F23-N48 WeakPolarHBondContact CE1-OD1 3.27Å; F23-N48 WeakPolarHBondContact CZ-OD1 3.22Å; N48-D50 PolarHBondContact O-N 2.71Å; N48-V51 WeakPolarHBondContact O-CG2 3.48Å; N48-V51 PolarHBondContact O-N 2.97Å; N48-L52 HydrophobicContact CB-CD1 4.05Å; N48-L52 WeakPolarHBondContact O-CD1 3.46Å; N48-L52 VanDerWaalsContact O-CG 3.23Å; N48-L52 WeakPolarHBondContact O-CG 3.17Å; N48-L52 PolarHBondContact O-N 3.25Å
49F94.1Very high96.9Very high118 Ų11836.1 Ų36.152%0.51819%0.193SC..G310 helixtrans-61.7-27.2-178.679.3-103.9000112.6Y47 V51 L52 A53Y47-F49 VanDerWaalsContact CB-CE1 3.47Å; Y47-F49 HydrophobicContact CD2-CD1 4.18Å; Y47-F49 AromaticContact CD2-CE1 3.39Å; Y47-F49 HydrophobicContact CD2-CE1 3.39Å; Y47-F49 HydrophobicContact CD2-CZ 4.12Å; Y47-F49 HydrophobicContact CE2-CE1 4.32Å; Y47-F49 HydrophobicContact CG-CD1 4.02Å; Y47-F49 AromaticContact CG-CE1 3.69Å; Y47-F49 HydrophobicContact CG-CE1 3.69Å; Y47-F49 PolarHBondContact O-N 2.69Å; Y47-F49 VanDerWaalsContact O-N 3.12Å; F49-V51 PolarHBondContact O-N 3.45Å; F49-L52 PolarHBondContact O-N 2.92Å; F49-A53 PolarHBondContact O-N 3.46Å
50D96.8Very high96.8Very high11 Ų1134.9 Ų34.96%0.05919%0.187CC..G310 helixtrans-63.5-14.1-179.8-63.7-48.7000113.2F39 I46 Y47 N48 H56 A69F39-D50 HydrophobicContact CD1-CB 4.08Å; F39-D50 HydrophobicContact CE1-CB 4.23Å; I46-D50 WeakPolarHBondContact CA-OD2 3.17Å; I46-D50 WeakPolarHBondContact CB-OD2 3.35Å; Y47-D50 PolarHBondContact N-OD2 3.14Å; Y47-D50 WeakPolarHBondContact O-CB 3.44Å; Y47-D50 PolarHBondContact O-N 3.42Å; Y47-D50 VanDerWaalsContact O-N 3.09Å; N48-D50 PolarHBondContact O-N 2.71Å; D50-H56 PolarHBondContact O-NE2 2.91Å; D50-A69 HydrophobicContact CB-CB 3.81Å
51V97.9Very high96.8Very high5 Ų540.9 Ų40.93%0.0321%0.213CC..G310 helixtrans-118.14.7171.8-60.40000113.3F23 N25 N48 F49 L67 A69F23-V51 HydrophobicContact CB-CG1 3.98Å; F23-V51 HydrophobicContact CB-CG2 3.84Å; N25-V51 HydrophobicContact CB-CB 3.85Å; N25-V51 HydrophobicContact CB-CG2 3.95Å; N25-V51 WeakPolarHBondContact CB-O 3.42Å; N25-V51 PolarHBondContact ND2-O 2.74Å; N48-V51 WeakPolarHBondContact O-CG2 3.48Å; N48-V51 PolarHBondContact O-N 2.97Å; F49-V51 PolarHBondContact O-N 3.45Å; V51-L67 HydrophobicContact CB-CB 4.38Å; V51-A69 HydrophobicContact CG1-CB 3.57Å
52L97.5Very high96.7Very high106 Ų10646.7 Ų46.756%0.55524%0.24SC*.THydrogen-bonded Turntrans-118.1-23.2-176.2-63.3173.8000113.9N48 F49N48-L52 HydrophobicContact CB-CD1 4.05Å; N48-L52 WeakPolarHBondContact O-CD1 3.46Å; N48-L52 VanDerWaalsContact O-CG 3.23Å; N48-L52 WeakPolarHBondContact O-CG 3.17Å; N48-L52 PolarHBondContact O-N 3.25Å; F49-L52 PolarHBondContact O-N 2.92Å
53A96.3Very high96.8Very high41 Ų4148.1 Ų48.134%0.33924%0.244SC..SBendtrans-147.6157.117900000111.6F49 H56 V57F49-A53 PolarHBondContact O-N 3.46Å; A53-H56 PolarHBondContact O-CE1 3.31Å; A53-V57 WeakPolarHBondContact O-CG2 3.46Å
54G96.5Very high96.9Very high6 Ų652 Ų526%0.06226%0.255CS..SBendtrans119.5163.9-177.900000111.4H56 V57 D58 M414G54-H56 VanDerWaalsContact C-N 3.29Å; G54-H56 PolarHBondContact O-N 2.9Å; G54-V57 WeakPolarHBondContact O-CA 3.28Å; G54-V57 WeakPolarHBondContact O-CB 3.39Å; G54-V57 PolarHBondContact O-N 2.92Å; G54-D58 PolarHBondContact O-N 3.48Å; G54-M414 CarbonylContact C-O 3.49Å; G54-M414 VanDerWaalsContact CA-O 3.32Å; G54-M414 WeakPolarHBondContact CA-O 3.35Å
55H97.6Very high97.1Very high6 Ų651 Ų513%0.02825%0.246CC..Hα-helixtrans-62.9-35.8-175.8-173.8-138.4000112.6V57 D58 M59 D413 M414 R429 E433H55-V57 VanDerWaalsContact C-N 3.27Å; H55-V57 PolarHBondContact O-N 3.18Å; H55-D58 PolarHBondContact O-N 3.35Å; H55-M59 WeakPolarHBondContact O-CG 3.41Å; H55-M59 PolarHBondContact O-N 2.75Å; H55-D413 WeakPolarHBondContact CB-O 3.49Å; H55-M414 PolarHBondContact N-O 3.04Å; H55-R429 PolarHBondContact CE1-O 3.41Å; H55-E433 IonicContact CD2-OE1 2.59Å; H55-E433 IonicContact CE1-OE1 2.71Å; H55-E433 WeakPolarHBondContact NE2-CG 3.47Å; H55-E433 IonicContact NE2-OE1 3.54Å; H55-E433 PolarHBondContact NE2-OE1 3.31Å
56H98.1Very high97.3Very high9 Ų948.9 Ų48.94%0.04223%0.232CC..Hα-helixtrans-63.4-31.7172.862.9-64.2000112.9F37 F39 D50 A53 G54 A60 F123F37-H56 WeakPolarHBondContact CD2-O 3.27Å; F39-H56 AromaticContact CD2-CD2 3.92Å; F39-H56 AromaticContact CD2-CE1 3.82Å; F39-H56 AromaticContact CD2-NE2 3.55Å; D50-H56 PolarHBondContact O-NE2 2.91Å; A53-H56 PolarHBondContact O-CE1 3.31Å; G54-H56 VanDerWaalsContact C-N 3.29Å; G54-H56 PolarHBondContact O-N 2.9Å; H56-A60 VanDerWaalsContact O-CB 3.28Å; H56-A60 WeakPolarHBondContact O-CB 3.31Å; H56-A60 PolarHBondContact O-N 3.23Å; H56-F123 HydrophobicContact CB-CB 4.27Å; H56-F123 HydrophobicContact CB-CD1 3.76Å; H56-F123 HydrophobicContact CB-CD2 4.19Å; H56-F123 HydrophobicContact CB-CE1 4.13Å; H56-F123 HydrophobicContact CB-CG 3.8Å; H56-F123 HydrophobicContact CB-CZ 4.5Å
57V98.3Very high97.4Very high3 Ų348.7 Ų48.72%0.01823%0.231CC..Hα-helixtrans-73.9-40.5175178.80000111Y28 A53 G54 H55 A60 K61 L67Y28-V57 HydrophobicContact CE2-CG1 4.16Å; A53-V57 WeakPolarHBondContact O-CG2 3.46Å; G54-V57 WeakPolarHBondContact O-CA 3.28Å; G54-V57 WeakPolarHBondContact O-CB 3.39Å; G54-V57 PolarHBondContact O-N 2.92Å; H55-V57 VanDerWaalsContact C-N 3.27Å; H55-V57 PolarHBondContact O-N 3.18Å; V57-A60 WeakPolarHBondContact O-CB 3.49Å; V57-A60 PolarHBondContact O-N 3.4Å; V57-K61 PolarHBondContact O-N 3.31Å; V57-L67 HydrophobicContact CB-CD1 4.19Å; V57-L67 HydrophobicContact CG1-CD1 3.81Å; V57-L67 HydrophobicContact CG2-CD1 4.05Å; V57-L67 HydrophobicContact CG2-CD2 4.29Å
58D97.3Very high97.5Very high59 Ų5942.9 Ų42.932%0.31621%0.208SC..Hα-helixtrans-62-46.3176-67.3-33.8000110.7G54 H55 A60 K61 E62G54-D58 PolarHBondContact O-N 3.48Å; H55-D58 PolarHBondContact O-N 3.35Å; D58-A60 PolarHBondContact O-N 3.21Å; D58-K61 WeakPolarHBondContact O-CB 3.36Å; D58-K61 PolarHBondContact O-N 3.39Å; D58-E62 PolarHBondContact O-N 3.32Å; D58-E62 VanDerWaalsContact O-N 3.16Å
59M97.9Very high97.7Very high3 Ų338.2 Ų38.22%0.01518%0.183CC..Hα-helixtrans-62.8-39.1173.1-71.5-172.9-78.600112.6F37 H55 K61 E62 H63 F123 I432 E433 V436F37-M59 HydrophobicContact CE2-CB 3.71Å; H55-M59 WeakPolarHBondContact O-CG 3.41Å; H55-M59 PolarHBondContact O-N 2.75Å; M59-K61 VanDerWaalsContact C-N 3.3Å; M59-K61 PolarHBondContact O-N 3.03Å; M59-E62 PolarHBondContact O-N 3.16Å; M59-H63 WeakPolarHBondContact O-CB 3.43Å; M59-H63 PolarHBondContact O-CD2 2.95Å; M59-H63 VanDerWaalsContact O-CD2 3.25Å; M59-H63 PolarHBondContact O-N 3.43Å; M59-F123 HydrophobicContact CE-CD1 4.39Å; M59-F123 HydrophobicContact CE-CE1 3.62Å; M59-F123 HydrophobicContact CE-CZ 4.35Å; M59-I432 HydrophobicContact CE-CG2 4.1Å; M59-I432 HydrophobicContact SD-CG2 4.29Å; M59-E433 HydrophobicContact CG-CG 3.74Å; M59-E433 HydrophobicContact SD-CB 4.43Å; M59-E433 HydrophobicContact SD-CG 3.84Å; M59-V436 HydrophobicContact SD-CB 4.21Å; M59-V436 HydrophobicContact SD-CG2 4.04Å
60A98Very high97.9Very high0 Ų032.6 Ų32.60%016%0.159CC..Hα-helixtrans-63.1-37.1176.600000112.2F37 H56 V57 D58 R64 A65 L67F37-A60 HydrophobicContact CD2-CB 3.65Å; F37-A60 HydrophobicContact CE2-CB 4.17Å; F37-A60 HydrophobicContact CG-CB 4.31Å; H56-A60 VanDerWaalsContact O-CB 3.28Å; H56-A60 WeakPolarHBondContact O-CB 3.31Å; H56-A60 PolarHBondContact O-N 3.23Å; V57-A60 WeakPolarHBondContact O-CB 3.49Å; V57-A60 PolarHBondContact O-N 3.4Å; D58-A60 PolarHBondContact O-N 3.21Å; A60-R64 CarbonylContact O-C 3.55Å; A60-R64 WeakPolarHBondContact O-CA 3.49Å; A60-R64 PolarHBondContact O-N 3.5Å; A60-A65 HydrophobicContact CB-CB 3.84Å; A60-A65 PolarHBondContact O-N 3.41Å; A60-L67 HydrophobicContact CB-CD1 3.66Å; A60-L67 HydrophobicContact CB-CD2 3.54Å; A60-L67 HydrophobicContact CB-CG 3.48Å; A60-L67 VanDerWaalsContact CB-CG 3.48Å
61K97.8Very high98Very high129 Ų12932.1 Ų32.156%0.56116%0.156SC*.Hα-helixtrans-63.5-44.2174.5-179.7-177.9174.8-171.50111.4Y28 V57 D58 M59Y28-K61 HydrophobicContact CD1-CB 4.21Å; Y28-K61 HydrophobicContact CD1-CG 3.88Å; Y28-K61 HydrophobicContact CD2-CB 4.03Å; Y28-K61 HydrophobicContact CE1-CB 4.41Å; Y28-K61 HydrophobicContact CE1-CD 4.17Å; Y28-K61 HydrophobicContact CE1-CG 4Å; Y28-K61 HydrophobicContact CE2-CB 4.22Å; Y28-K61 HydrophobicContact CG-CB 4.03Å; Y28-K61 HydrophobicContact CG-CG 4.2Å; V57-K61 PolarHBondContact O-N 3.31Å; D58-K61 WeakPolarHBondContact O-CB 3.36Å; D58-K61 PolarHBondContact O-N 3.39Å; M59-K61 VanDerWaalsContact C-N 3.3Å; M59-K61 PolarHBondContact O-N 3.03Å
62E97.6Very high98Very high125 Ų12532.1 Ų32.158%0.58416%0.156SC*.Hα-helixtrans-63.6-45.7177.6-175.9176.9172.200112.1D58 M59 R64D58-E62 PolarHBondContact O-N 3.32Å; D58-E62 VanDerWaalsContact O-N 3.16Å; M59-E62 PolarHBondContact O-N 3.16Å; E62-R64 VanDerWaalsContact C-N 3.32Å; E62-R64 PolarHBondContact O-N 3.21Å
63H98Very high98Very high41 Ų4127.1 Ų27.119%0.1913%0.129CC..Hα-helixtrans-88.84.6-177.1-64.9-53.7000114.5P35 F37 M59 A65 L440P35-H63 WeakPolarHBondContact CD-O 3.15Å; P35-H63 HydrophobicContact CG-CB 4.29Å; F37-H63 HydrophobicContact CZ-CB 4.35Å; M59-H63 WeakPolarHBondContact O-CB 3.43Å; M59-H63 PolarHBondContact O-CD2 2.95Å; M59-H63 VanDerWaalsContact O-CD2 3.25Å; M59-H63 PolarHBondContact O-N 3.43Å; H63-A65 VanDerWaalsContact C-N 3.29Å; H63-A65 PolarHBondContact O-N 2.93Å; H63-L440 HydrophobicContact CB-CD1 3.85Å
64R98.3Very high98Very high140 Ų14025.8 Ų25.853%0.52812%0.116SC..THydrogen-bonded Turntrans53.145.2-179.3-55.2174.2178.4178.1-2112.7Y28 W29 Q30 A60 E62Y28-R64 CarbonylContact O-C 3.57Å; Y28-R64 VanDerWaalsContact O-C 3.28Å; Y28-R64 WeakPolarHBondContact O-CA 3.38Å; Y28-R64 VanDerWaalsContact O-CB 3.31Å; Y28-R64 WeakPolarHBondContact O-CB 3.4Å; W29-R64 WeakPolarHBondContact CA-O 3.46Å; Q30-R64 HydrophobicContact CB-CB 3.69Å; Q30-R64 HydrophobicContact CB-CG 4.5Å; Q30-R64 PolarHBondContact N-O 3.13Å; A60-R64 CarbonylContact O-C 3.55Å; A60-R64 WeakPolarHBondContact O-CA 3.49Å; A60-R64 PolarHBondContact O-N 3.5Å; E62-R64 VanDerWaalsContact C-N 3.32Å; E62-R64 PolarHBondContact O-N 3.21Å
65A98.6Very high98Very high0 Ų025.6 Ų25.60%011%0.113CC..PPolyproline II helixtrans-85.1152.1-175.200000112.7P35 F37 A60 H63P35-A65 HydrophobicContact CG-CB 3.85Å; P35-A65 CarbonylContact O-C 3.6Å; P35-A65 WeakPolarHBondContact O-CA 3.32Å; P35-A65 WeakPolarHBondContact O-CB 3.35Å; F37-A65 HydrophobicContact CB-CB 4.34Å; F37-A65 HydrophobicContact CD1-CB 3.83Å; F37-A65 HydrophobicContact CD2-CB 4.24Å; F37-A65 HydrophobicContact CE1-CB 4.16Å; F37-A65 HydrophobicContact CG-CB 3.86Å; F37-A65 HydrophobicContact CZ-CB 4.49Å; A60-A65 HydrophobicContact CB-CB 3.84Å; A60-A65 PolarHBondContact O-N 3.41Å; H63-A65 VanDerWaalsContact C-N 3.29Å; H63-A65 PolarHBondContact O-N 2.93Å
66L98.8Very high97.9Very high0 Ų025.4 Ų25.40%011%0.113CC..EExtended strand (participates in β ladder)trans-74.4125.4160.9177.361.8000108.8V24 E26 W29 P35 V36 F37 L68 F112 L114V24-L66 HydrophobicContact CG1-CD1 3.81Å; E26-L66 HydrophobicContact CB-CD1 4.48Å; E26-L66 HydrophobicContact CG-CD1 3.88Å; W29-L66 HydrophobicContact CB-CB 4.2Å; W29-L66 HydrophobicContact CD2-CB 3.87Å; W29-L66 HydrophobicContact CD2-CD1 4.24Å; W29-L66 HydrophobicContact CD2-CG 4.44Å; W29-L66 HydrophobicContact CE3-CB 4.46Å; W29-L66 HydrophobicContact CE3-CD1 4.02Å; W29-L66 HydrophobicContact CE3-CD2 4.49Å; W29-L66 HydrophobicContact CG-CB 3.69Å; W29-L66 HydrophobicContact CG-CD1 4.45Å; P35-L66 PolarHBondContact O-N 3.16Å; V36-L66 WeakPolarHBondContact CA-O 3.34Å; V36-L66 HydrophobicContact CG1-CB 4.47Å; V36-L66 HydrophobicContact CG1-CD2 4.45Å; V36-L66 HydrophobicContact CG2-CB 4.33Å; V36-L66 HydrophobicContact CG2-CD2 4.38Å; F37-L66 PolarHBondContact N-O 3.14Å; L66-L68 HydrophobicContact CD2-CD2 4.37Å; L66-L68 HydrophobicContact CG-CD2 4.28Å; L66-L68 HydrophobicContact CG-CG 4.36Å; L66-F112 HydrophobicContact CD2-CD1 4.32Å; L66-F112 HydrophobicContact CD2-CG 4.23Å; L66-L114 HydrophobicContact CD2-CD1 4.33Å; L66-L114 HydrophobicContact CD2-CD2 4.5Å
67L98.6Very high97.7Very high0 Ų028.7 Ų28.70%013%0.131CC..EExtended strand (participates in β ladder)trans-98.7132.5177.8-82.4163.3000111.2V24 N25 Y28 F37 V51 V57 A60V24-L67 CarbonylContact C-O 3.55Å; V24-L67 WeakPolarHBondContact CA-O 3.45Å; N25-L67 HydrophobicContact CB-CB 3.99Å; N25-L67 HydrophobicContact CB-CD1 4.47Å; N25-L67 PolarHBondContact N-O 3.02Å; N25-L67 PolarHBondContact O-N 3.21Å; N25-L67 VanDerWaalsContact O-N 3.07Å; Y28-L67 HydrophobicContact CD2-CD1 4.15Å; Y28-L67 HydrophobicContact CE2-CD1 4.39Å; F37-L67 HydrophobicContact CB-CD2 3.92Å; V51-L67 HydrophobicContact CB-CB 4.38Å; V57-L67 HydrophobicContact CB-CD1 4.19Å; V57-L67 HydrophobicContact CG1-CD1 3.81Å; V57-L67 HydrophobicContact CG2-CD1 4.05Å; V57-L67 HydrophobicContact CG2-CD2 4.29Å; A60-L67 HydrophobicContact CB-CD1 3.66Å; A60-L67 HydrophobicContact CB-CD2 3.54Å; A60-L67 HydrophobicContact CB-CG 3.48Å; A60-L67 VanDerWaalsContact CB-CG 3.48Å
68L98.8Very high97.6Very high0 Ų028.6 Ų28.60%013%0.131CC..EExtended strand (participates in β ladder)trans-131.7142.5177.4-56.1168.4000109.1F23 V24 V36 F37 L38 F39 L66 F104 I108 W120F23-L68 WeakPolarHBondContact O-CA 3.49Å; V24-L68 HydrophobicContact CB-CD2 4.23Å; V24-L68 HydrophobicContact CG1-CD2 3.93Å; V24-L68 HydrophobicContact CG2-CD2 3.72Å; V36-L68 HydrophobicContact CG1-CD1 3.37Å; V36-L68 HydrophobicContact CG1-CG 4.11Å; F37-L68 PolarHBondContact O-N 3.3Å; L38-L68 HydrophobicContact CD1-CB 3.82Å; L38-L68 HydrophobicContact CD1-CD1 4.48Å; F39-L68 PolarHBondContact N-O 2.96Å; L66-L68 HydrophobicContact CD2-CD2 4.37Å; L66-L68 HydrophobicContact CG-CD2 4.28Å; L66-L68 HydrophobicContact CG-CG 4.36Å; L68-F104 HydrophobicContact CB-CE1 4.45Å; L68-F104 HydrophobicContact CD1-CE1 4.35Å; L68-I108 HydrophobicContact CD1-CB 4.47Å; L68-I108 HydrophobicContact CD1-CG1 4.28Å; L68-I108 HydrophobicContact CD1-CG2 3.73Å; L68-I108 HydrophobicContact CD2-CD1 4.12Å; L68-I108 HydrophobicContact CD2-CG1 4.49Å; L68-I108 HydrophobicContact CD2-CG2 4.29Å; L68-W120 HydrophobicContact CD1-CH2 3.64Å; L68-W120 HydrophobicContact CD1-CZ3 3.56Å
69A98.8Very high97.3Very high0 Ų027.1 Ų27.10%012%0.122CC..EExtended strand (participates in β ladder)trans-128.4129.3163.400000108.9F22 F23 F39 I46 D50 V51F22-A69 CarbonylContact C-O 3.57Å; F22-A69 WeakPolarHBondContact CA-O 3.29Å; F22-A69 WeakPolarHBondContact CB-O 3.45Å; F23-A69 HydrophobicContact CB-CB 4.45Å; F23-A69 PolarHBondContact N-O 3.47Å; F23-A69 PolarHBondContact O-N 2.95Å; F39-A69 HydrophobicContact CB-CB 4.1Å; F39-A69 HydrophobicContact CD1-CB 4.21Å; F39-A69 VanDerWaalsContact O-CA 3.28Å; F39-A69 WeakPolarHBondContact O-CA 3.46Å; I46-A69 HydrophobicContact CD1-CB 4.39Å; D50-A69 HydrophobicContact CB-CB 3.81Å; V51-A69 HydrophobicContact CG1-CB 3.57Å
70V98.8Very high97Very high1 Ų128.4 Ų28.41%0.00613%0.13CC..EExtended strand (participates in β ladder)trans-119.3132.9-178.463.40000110.7Q20 F22 L38 F39 G41 L101 F104Q20-V70 HydrophobicContact CG-CG2 4.12Å; F22-V70 HydrophobicContact CB-CB 4.36Å; F22-V70 HydrophobicContact CB-CG2 4.36Å; L38-V70 HydrophobicContact CD1-CB 4.45Å; L38-V70 HydrophobicContact CD1-CG1 3.88Å; F39-V70 PolarHBondContact O-N 3.4Å; F39-V70 VanDerWaalsContact O-N 3.07Å; G41-V70 WeakPolarHBondContact CA-O 3.28Å; G41-V70 PolarHBondContact N-O 3.18Å; V70-L101 HydrophobicContact CG1-CD2 3.45Å; V70-L101 VanDerWaalsContact CG1-CD2 3.45Å; V70-F104 HydrophobicContact CB-CD1 3.9Å; V70-F104 HydrophobicContact CB-CE1 3.73Å; V70-F104 HydrophobicContact CB-CG 4.37Å; V70-F104 HydrophobicContact CB-CZ 4.06Å; V70-F104 HydrophobicContact CG1-CD1 4.12Å; V70-F104 HydrophobicContact CG1-CE1 4.21Å; V70-F104 HydrophobicContact CG2-CD1 3.95Å; V70-F104 HydrophobicContact CG2-CD2 4.1Å; V70-F104 HydrophobicContact CG2-CE1 4.14Å; V70-F104 HydrophobicContact CG2-CE2 4.28Å; V70-F104 HydrophobicContact CG2-CG 3.91Å; V70-F104 HydrophobicContact CG2-CZ 4.29Å
71E98.7Very high96.6Very high1 Ų133.9 Ų33.91%0.00517%0.165CC..PPolyproline II helixtrans-80.1142.8-175.9-169157.4-102.800111.5Q20 R21 P45 I46 Y75 D77 S78Q20-E71 VanDerWaalsContact CG-O 3.31Å; Q20-E71 WeakPolarHBondContact CG-O 3.27Å; Q20-E71 PolarHBondContact NE2-O 3.39Å; R21-E71 HydrophobicContact CB-CB 4.11Å; R21-E71 WeakPolarHBondContact CB-OE2 3.37Å; R21-E71 IonicContact CZ-OE1 3.77Å; R21-E71 VanDerWaalsContact CZ-OE1 3.25Å; R21-E71 IonicContact CZ-OE2 3.34Å; R21-E71 IonicContact NE-OE1 3.59Å; R21-E71 PolarHBondContact NE-OE1 2.98Å; R21-E71 VanDerWaalsContact NE-OE1 3.13Å; R21-E71 IonicContact NE-OE2 2.93Å; R21-E71 PolarHBondContact NE-OE2 2.79Å; R21-E71 VanDerWaalsContact NE-OE2 3.1Å; R21-E71 IonicContact NH2-OE1 3.36Å; R21-E71 PolarHBondContact NH2-OE1 3.09Å; R21-E71 IonicContact NH2-OE2 2.83Å; R21-E71 VanDerWaalsContact O-CB 3.28Å; R21-E71 WeakPolarHBondContact O-CB 3.5Å; R21-E71 PolarHBondContact O-N 3.32Å; P45-E71 WeakPolarHBondContact CA-OE1 3.34Å; I46-E71 HydrophobicContact CD1-CB 3.74Å; I46-E71 HydrophobicContact CG1-CB 3.71Å; I46-E71 HydrophobicContact CG1-CG 4.09Å; I46-E71 WeakPolarHBondContact CG1-OE1 3.35Å; I46-E71 HydrophobicContact CG2-CB 4.39Å; I46-E71 PolarHBondContact N-OE1 3.34Å; E71-Y75 VanDerWaalsContact CD-O 3.31Å; E71-D77 PolarHBondContact OE2-N 3.16Å; E71-S78 VanDerWaalsContact CB-OG 3.32Å; E71-S78 WeakPolarHBondContact CB-OG 3.38Å; E71-S78 WeakPolarHBondContact CG-OG 2.88Å; E71-S78 PolarHBondContact OE2-N 3.29Å; E71-S78 PolarHBondContact OE2-OG 2.84Å
72H98.6Very high96.1Very high5 Ų531.4 Ų31.42%0.02316%0.158CC..PPolyproline II helixtrans-68.7141.3175-163.8-72.5000111.5G42 Y75 A97 Y127 L131G42-H72 WeakPolarHBondContact O-CB 3.32Å; H72-Y75 HydrophobicContact CB-CD2 3.78Å; H72-Y75 HydrophobicContact CB-CG 4.48Å; H72-Y75 AromaticContact CG-CD2 3.76Å; H72-Y75 AromaticContact ND1-CD2 3.42Å; H72-Y75 WeakPolarHBondContact ND1-CD2 3.38Å; H72-Y75 AromaticContact ND1-CE2 3.6Å; H72-Y75 PolarHBondContact O-N 2.85Å; H72-Y75 VanDerWaalsContact O-N 3.15Å; H72-A97 WeakPolarHBondContact NE2-CB 3.01Å; H72-Y127 AromaticContact CD2-CE1 3.69Å; H72-Y127 AromaticContact NE2-CE1 3.5Å; H72-Y127 WeakPolarHBondContact NE2-CE1 3.48Å; H72-Y127 AromaticContact NE2-CZ 3.51Å; H72-Y127 PolarHBondContact NE2-OH 3.13Å; H72-L131 VanDerWaalsContact CD2-CD1 3.43Å; H72-L131 WeakPolarHBondContact CD2-CD1 3.17Å
73R97.8Very high95.5Very high0 Ų025.7 Ų25.70%013%0.132CC..THydrogen-bonded Turntrans-52.9142.4170.659.3166.258.7-148.3-7.2111.2P6 L7 H9 F18 Y75 D91 L92 Q96 A97 D100P6-R73 PolarHBondContact O-NH2 3.16Å; L7-R73 PolarHBondContact O-NH1 2.84Å; H9-R73 PolarHBondContact CD2-NH2 3.03Å; H9-R73 VanDerWaalsContact CD2-NH2 3.27Å; H9-R73 PolarHBondContact NE2-NH2 3.05Å; F18-R73 HydrophobicContact CE1-CB 4.4Å; F18-R73 HydrophobicContact CE2-CB 3.87Å; F18-R73 HydrophobicContact CZ-CB 3.61Å; R73-Y75 VanDerWaalsContact O-CD2 3.27Å; R73-Y75 WeakPolarHBondContact O-CD2 2.86Å; R73-Y75 PolarHBondContact O-N 3.28Å; R73-D91 WeakPolarHBondContact CD-O 3.27Å; R73-D91 PolarHBondContact NH1-O 2.55Å; R73-L92 HydrophobicContact CG-CD1 4.44Å; R73-Q96 VanDerWaalsContact NH1-CB 3.31Å; R73-A97 HydrophobicContact CG-CB 4.35Å; R73-D100 IonicContact CZ-OD1 3.32Å; R73-D100 IonicContact CZ-OD2 3.64Å; R73-D100 IonicContact NE-OD1 2.69Å; R73-D100 IonicContact NE-OD2 2.75Å; R73-D100 PolarHBondContact NE-OD2 3.49Å; R73-D100 VanDerWaalsContact NH2-CG 3.25Å; R73-D100 IonicContact NH2-OD1 3.14Å; R73-D100 PolarHBondContact NH2-OD1 3.48Å; R73-D100 IonicContact NH2-OD2 3.76Å; R73-D100 PolarHBondContact NH2-OD2 2.99Å; R73-D100 VanDerWaalsContact NH2-OD2 3.14Å
74F96.4Very high95.3Very high14 Ų1423.7 Ų23.76%0.06112%0.123CC..THydrogen-bonded Turntrans66.82.9-177.1-61.9-94.2000116.4S78 I79 L84 N88 L89 D91 L92 Q310F74-S78 PolarHBondContact N-O 3.01Å; F74-I79 VanDerWaalsContact O-CD1 3.29Å; F74-I79 WeakPolarHBondContact O-CD1 3.03Å; F74-L84 HydrophobicContact CD1-CD2 4.03Å; F74-N88 HydrophobicContact CE1-CB 4.43Å; F74-N88 WeakPolarHBondContact CE1-O 3.15Å; F74-N88 WeakPolarHBondContact CZ-O 3.46Å; F74-L89 HydrophobicContact CD1-CD2 3.86Å; F74-L89 HydrophobicContact CE1-CD2 4.24Å; F74-D91 HydrophobicContact CE2-CB 3.9Å; F74-D91 HydrophobicContact CZ-CB 3.92Å; F74-L92 HydrophobicContact CB-CD1 4.06Å; F74-L92 HydrophobicContact CB-CD2 4.15Å; F74-L92 HydrophobicContact CB-CG 4.46Å; F74-L92 HydrophobicContact CD2-CB 3.72Å; F74-L92 HydrophobicContact CD2-CD1 4.08Å; F74-L92 HydrophobicContact CD2-CG 4.4Å; F74-L92 HydrophobicContact CE2-CB 4.08Å; F74-L92 HydrophobicContact CG-CB 4.04Å; F74-L92 HydrophobicContact CG-CD1 4.35Å; F74-L92 HydrophobicContact CG-CD2 4.48Å; F74-Q310 HydrophobicContact CB-CG 3.98Å; F74-Q310 WeakPolarHBondContact O-CG 3.36Å; F74-Q310 PolarHBondContact O-NE2 2.99Å
75Y96.3Very high95.1Very high1 Ų122 Ų220%0.00412%0.12CC..SBendtrans-114.9156.2173.1-63.3-86.8000111.5E43 E71 H72 R73 D77 S78 L92 A307 Q310 W311 Q314E43-Y75 VanDerWaalsContact C-CE1 3.41Å; E43-Y75 VanDerWaalsContact CA-CE1 3.43Å; E43-Y75 HydrophobicContact CB-CE1 3.87Å; E43-Y75 WeakPolarHBondContact O-CD1 3.3Å; E43-Y75 WeakPolarHBondContact O-CE1 3.28Å; E71-Y75 VanDerWaalsContact CD-O 3.31Å; H72-Y75 HydrophobicContact CB-CD2 3.78Å; H72-Y75 HydrophobicContact CB-CG 4.48Å; H72-Y75 AromaticContact CG-CD2 3.76Å; H72-Y75 AromaticContact ND1-CD2 3.42Å; H72-Y75 WeakPolarHBondContact ND1-CD2 3.38Å; H72-Y75 AromaticContact ND1-CE2 3.6Å; H72-Y75 PolarHBondContact O-N 2.85Å; H72-Y75 VanDerWaalsContact O-N 3.15Å; R73-Y75 VanDerWaalsContact O-CD2 3.27Å; R73-Y75 WeakPolarHBondContact O-CD2 2.86Å; R73-Y75 PolarHBondContact O-N 3.28Å; Y75-D77 PolarHBondContact O-N 2.77Å; Y75-S78 WeakPolarHBondContact O-CB 3.16Å; Y75-S78 PolarHBondContact O-N 2.9Å; Y75-L92 HydrophobicContact CE2-CD1 4.09Å; Y75-A307 HydrophobicContact CD1-CB 4.24Å; Y75-A307 HydrophobicContact CE1-CB 4.37Å; Y75-Q310 HydrophobicContact CD1-CB 4.33Å; Y75-Q310 HydrophobicContact CE1-CB 3.53Å; Y75-Q310 HydrophobicContact CE1-CG 4.33Å; Y75-Q310 HydrophobicContact CE2-CB 4.29Å; Y75-Q310 WeakPolarHBondContact OH-CB 3.43Å; Y75-W311 WeakPolarHBondContact OH-CA 3.4Å; Y75-W311 PolarHBondContact OH-N 3.07Å; Y75-Q314 PolarHBondContact OH-OE1 2.91Å
76G94.2Very high94.9Very high3 Ų324.1 Ų24.13%0.03113%0.133CC..THydrogen-bonded Turntrans54.1-121.2-178.500000113.9I79 R306G76-I79 WeakPolarHBondContact O-CD1 3.1Å; G76-R306 PolarHBondContact O-NH1 2.64Å; G76-R306 PolarHBondContact O-NH2 3.44Å
77D93.8Very high94.7Very high78 Ų7830.6 Ų30.642%0.41716%0.163SC..THydrogen-bonded Turntrans-99.77.2-179.8-63.5-22.7000112.4R21 E71 Y75 I79R21-D77 IonicContact CZ-OD2 3.8Å; R21-D77 IonicContact NE-OD2 2.76Å; R21-D77 IonicContact NH1-OD2 2.68Å; R21-D77 PolarHBondContact NH1-OD2 3.44Å; E71-D77 PolarHBondContact OE2-N 3.16Å; Y75-D77 PolarHBondContact O-N 2.77Å; D77-I79 VanDerWaalsContact C-N 3.27Å; D77-I79 PolarHBondContact O-N 3.33Å
78S96.1Very high94.5Very high1 Ų131.9 Ų31.91%0.00717%0.17CC..  trans-95.149.6-179.2-58.20000111.4R21 E71 F74 Y75R21-S78 PolarHBondContact N-OG 3.4Å; E71-S78 VanDerWaalsContact CB-OG 3.32Å; E71-S78 WeakPolarHBondContact CB-OG 3.38Å; E71-S78 WeakPolarHBondContact CG-OG 2.88Å; E71-S78 PolarHBondContact OE2-N 3.29Å; E71-S78 PolarHBondContact OE2-OG 2.84Å; F74-S78 PolarHBondContact N-O 3.01Å; Y75-S78 WeakPolarHBondContact O-CB 3.16Å; Y75-S78 PolarHBondContact O-N 2.9Å
79I92.6Very high94.3Very high27 Ų2731.9 Ų31.914%0.13817%0.17CC..  trans-130.9135.2-174.4-42.7-175.4000108.6F74 G76 D77 L84F74-I79 VanDerWaalsContact O-CD1 3.29Å; F74-I79 WeakPolarHBondContact O-CD1 3.03Å; G76-I79 WeakPolarHBondContact O-CD1 3.1Å; D77-I79 VanDerWaalsContact C-N 3.27Å; D77-I79 PolarHBondContact O-N 3.33Å; I79-L84 HydrophobicContact CD1-CD2 4.46Å; I79-L84 HydrophobicContact CG2-CD2 3.88Å; I79-L84 HydrophobicContact CG2-CG 4.45Å
80N91.7Very high94.1Very high31 Ų3135 Ų3517%0.16620%0.195CC..  trans-71.9154.1174.2-86.8-17000112.1T17 F18 D82 G83T17-N80 PolarHBondContact O-ND2 3.33Å; F18-N80 VanDerWaalsContact CA-OD1 3.28Å; F18-N80 WeakPolarHBondContact CA-OD1 3.41Å; F18-N80 WeakPolarHBondContact CB-OD1 3.49Å; N80-D82 WeakPolarHBondContact CB-OD1 3.02Å; N80-D82 PolarHBondContact O-N 3.15Å; N80-G83 PolarHBondContact O-N 2.74Å; N80-G83 VanDerWaalsContact O-N 3.12Å
81P88.3Confident94Very high114 Ų11436 Ų3674%0.7420%0.201SC*.THydrogen-bonded Turntrans-63.6-19.1-179.9-24.335.1000115.1G83P81-G83 PolarHBondContact O-N 3.12Å
82D86.9Confident94Very high77 Ų7736 Ų3641%0.41220%0.201SC..THydrogen-bonded Turntrans-69.2-717556.60.4000113.3N80 N88N80-D82 WeakPolarHBondContact CB-OD1 3.02Å; N80-D82 PolarHBondContact O-N 3.15Å; D82-N88 PolarHBondContact O-ND2 3.25Å
83G86.1Confident94Very high5 Ų536.7 Ų36.75%0.05221%0.206CC..  trans80.2-159.4162.400000114.2N80 P81 N88N80-G83 PolarHBondContact O-N 2.74Å; N80-G83 VanDerWaalsContact O-N 3.12Å; P81-G83 PolarHBondContact O-N 3.12Å; G83-N88 PolarHBondContact O-ND2 2.67Å
84L93.1Very high94Very high0 Ų036.7 Ų36.70%021%0.206CC..  trans-109.229.1-164.7-60.1166000112.8F74 I79 L89 T299 R306 R309 Q310F74-L84 HydrophobicContact CD1-CD2 4.03Å; I79-L84 HydrophobicContact CD1-CD2 4.46Å; I79-L84 HydrophobicContact CG2-CD2 3.88Å; I79-L84 HydrophobicContact CG2-CG 4.45Å; L84-L89 HydrophobicContact CD2-CD2 4.07Å; L84-T299 PolarHBondContact N-O 3.27Å; L84-R306 HydrophobicContact CD1-CB 3.77Å; L84-R309 PolarHBondContact O-NE 3.03Å; L84-R309 PolarHBondContact O-NH2 3.21Å; L84-Q310 VanDerWaalsContact CD1-OE1 3.26Å; L84-Q310 HydrophobicContact CD2-CG 4.08Å
85K93.8Very high94.1Very high103 Ų10337.2 Ų37.245%0.44821%0.209SC..  trans-56.4145.9170.9-65.3-176.9-178.6179.30109.7E87 N88 L89 T299K85-E87 HydrophobicContact CB-CG 3.94Å; K85-E87 WeakPolarHBondContact CD-OE1 3.27Å; K85-E87 IonicContact NZ-OE1 3.88Å; K85-E87 PolarHBondContact O-N 3.23Å; K85-E87 VanDerWaalsContact O-N 3.13Å; K85-N88 WeakPolarHBondContact O-CB 3.47Å; K85-N88 PolarHBondContact O-N 3.24Å; K85-L89 PolarHBondContact O-N 3.35Å; K85-T299 HydrophobicContact CG-CG2 4.39Å
86T94.6Very high94.2Very high46 Ų4637.5 Ų37.528%0.28221%0.21SC..THydrogen-bonded Turntrans-54.8-35.9-177.3-52.80000112.5N88 L89 R309 Y313 F349T86-N88 VanDerWaalsContact C-N 3.32Å; T86-N88 PolarHBondContact O-N 3.19Å; T86-L89 PolarHBondContact O-N 3.12Å; T86-R309 PolarHBondContact OG1-NH2 2.9Å; T86-Y313 HydrophobicContact CG2-CE2 4.3Å; T86-F349 HydrophobicContact CG2-CB 3.99Å; T86-F349 HydrophobicContact CG2-CD1 4.06Å
87E94.5Very high94.5Very high136 Ų13637.6 Ų37.664%0.63621%0.211SC*.THydrogen-bonded Turntrans-61.5-34.5174.864.4-159.4-16900113.7K85 A90K85-E87 HydrophobicContact CB-CG 3.94Å; K85-E87 WeakPolarHBondContact CD-OE1 3.27Å; K85-E87 IonicContact NZ-OE1 3.88Å; K85-E87 PolarHBondContact O-N 3.23Å; K85-E87 VanDerWaalsContact O-N 3.13Å; E87-A90 WeakPolarHBondContact O-CB 3.32Å
88N94.4Very high94.7Very high27 Ų2734 Ų3414%0.14419%0.191CC..G310 helixtrans-76.9-30.1176.8-61.1-12.3000111.5F74 D82 G83 K85 T86 A90 D91F74-N88 HydrophobicContact CE1-CB 4.43Å; F74-N88 WeakPolarHBondContact CE1-O 3.15Å; F74-N88 WeakPolarHBondContact CZ-O 3.46Å; D82-N88 PolarHBondContact O-ND2 3.25Å; G83-N88 PolarHBondContact O-ND2 2.67Å; K85-N88 WeakPolarHBondContact O-CB 3.47Å; K85-N88 PolarHBondContact O-N 3.24Å; T86-N88 VanDerWaalsContact C-N 3.32Å; T86-N88 PolarHBondContact O-N 3.19Å; N88-A90 PolarHBondContact O-N 3.19Å; N88-A90 VanDerWaalsContact O-N 3.16Å; N88-D91 PolarHBondContact O-N 3.05Å
89L96Very high94.8Very high0 Ų034.4 Ų34.40%020%0.195CC..G310 helixtrans-67.9-8.3176.6-61.1179.3000112.6F74 L84 K85 T86 D91 L92 Q310 Y313 F349F74-L89 HydrophobicContact CD1-CD2 3.86Å; F74-L89 HydrophobicContact CE1-CD2 4.24Å; L84-L89 HydrophobicContact CD2-CD2 4.07Å; K85-L89 PolarHBondContact O-N 3.35Å; T86-L89 PolarHBondContact O-N 3.12Å; L89-D91 PolarHBondContact O-N 3.09Å; L89-D91 VanDerWaalsContact O-N 3.14Å; L89-L92 HydrophobicContact CD2-CB 4.48Å; L89-L92 HydrophobicContact CD2-CD2 4.06Å; L89-L92 VanDerWaalsContact O-CB 3.31Å; L89-L92 WeakPolarHBondContact O-CB 3.35Å; L89-L92 PolarHBondContact O-N 2.65Å; L89-Q310 HydrophobicContact CD2-CG 4.19Å; L89-Y313 HydrophobicContact CB-CD1 3.89Å; L89-Y313 HydrophobicContact CB-CD2 3.93Å; L89-Y313 HydrophobicContact CB-CE1 3.79Å; L89-Y313 HydrophobicContact CB-CE2 3.82Å; L89-Y313 HydrophobicContact CB-CG 3.94Å; L89-Y313 HydrophobicContact CD1-CD1 4.48Å; L89-Y313 HydrophobicContact CD1-CD2 3.83Å; L89-Y313 HydrophobicContact CD1-CE2 4.48Å; L89-Y313 HydrophobicContact CD1-CG 3.81Å; L89-Y313 HydrophobicContact CG-CG 4.46Å; L89-Y313 WeakPolarHBondContact O-CE1 3.48Å; L89-Y313 VanDerWaalsContact O-CZ 3.3Å; L89-Y313 PolarHBondContact O-OH 3.38Å; L89-F349 HydrophobicContact CD1-CD1 4.37Å; L89-F349 HydrophobicContact CD1-CE1 3.88Å
90A94.5Very high95.1Very high64 Ų6433.2 Ų33.253%0.52919%0.189SC..G310 helixtrans-55.4-29.1171.300000112.8E87 N88E87-A90 WeakPolarHBondContact O-CB 3.32Å; N88-A90 PolarHBondContact O-N 3.19Å; N88-A90 VanDerWaalsContact O-N 3.16Å
91D96.2Very high95.5Very high22 Ų2232 Ų3212%0.11818%0.182CC..G310 helixtrans-88.7-0.9176.7-61.5-50.6000113.2L7 R73 F74 N88 L89 S93L7-D91 HydrophobicContact CD1-CB 4.14Å; L7-D91 HydrophobicContact CG-CB 4.32Å; L7-D91 WeakPolarHBondContact CG-OD2 3.31Å; R73-D91 WeakPolarHBondContact CD-O 3.27Å; R73-D91 PolarHBondContact NH1-O 2.55Å; F74-D91 HydrophobicContact CE2-CB 3.9Å; F74-D91 HydrophobicContact CZ-CB 3.92Å; N88-D91 PolarHBondContact O-N 3.05Å; L89-D91 PolarHBondContact O-N 3.09Å; L89-D91 VanDerWaalsContact O-N 3.14Å; D91-S93 PolarHBondContact O-N 3.27Å
92L98.1Very high96Very high2 Ų227.5 Ų27.51%0.0116%0.155CC..  trans-87.698.9172.1176.554.3000109.5R73 F74 Y75 L89 Q310 Y313 Q314R73-L92 HydrophobicContact CG-CD1 4.44Å; F74-L92 HydrophobicContact CB-CD1 4.06Å; F74-L92 HydrophobicContact CB-CD2 4.15Å; F74-L92 HydrophobicContact CB-CG 4.46Å; F74-L92 HydrophobicContact CD2-CB 3.72Å; F74-L92 HydrophobicContact CD2-CD1 4.08Å; F74-L92 HydrophobicContact CD2-CG 4.4Å; F74-L92 HydrophobicContact CE2-CB 4.08Å; F74-L92 HydrophobicContact CG-CB 4.04Å; F74-L92 HydrophobicContact CG-CD1 4.35Å; F74-L92 HydrophobicContact CG-CD2 4.48Å; Y75-L92 HydrophobicContact CE2-CD1 4.09Å; L89-L92 HydrophobicContact CD2-CB 4.48Å; L89-L92 HydrophobicContact CD2-CD2 4.06Å; L89-L92 VanDerWaalsContact O-CB 3.31Å; L89-L92 WeakPolarHBondContact O-CB 3.35Å; L89-L92 PolarHBondContact O-N 2.65Å; L92-Q310 HydrophobicContact CD2-CB 3.64Å; L92-Q310 HydrophobicContact CD2-CG 3.78Å; L92-Y313 HydrophobicContact CB-CD1 4.39Å; L92-Y313 HydrophobicContact CB-CE1 4.42Å; L92-Y313 HydrophobicContact CD2-CD1 4.2Å; L92-Y313 HydrophobicContact CG-CD1 4.4Å; L92-Q314 HydrophobicContact CD1-CG 4.26Å; L92-Q314 HydrophobicContact CD2-CG 3.98Å; L92-Q314 HydrophobicContact CG-CG 3.84Å
93S98.5Very high96.5Very high19 Ų1925.8 Ų25.813%0.13315%0.147CC..SBendtrans-150.1158.1170.561.80000111.5D91 Q95 Q96 A97 E318D91-S93 PolarHBondContact O-N 3.27Å; S93-Q95 VanDerWaalsContact C-N 3.27Å; S93-Q95 PolarHBondContact O-N 3.49Å; S93-Q95 PolarHBondContact OG-OE1 2.95Å; S93-Q96 PolarHBondContact O-N 3.3Å; S93-Q96 WeakPolarHBondContact OG-CB 3.48Å; S93-Q96 WeakPolarHBondContact OG-CG 3.48Å; S93-Q96 PolarHBondContact OG-N 3.39Å; S93-A97 PolarHBondContact O-N 2.97Å; S93-E318 VanDerWaalsContact CA-OE2 3.3Å; S93-E318 WeakPolarHBondContact CA-OE2 3.43Å
94S98.6Very high97.1Very high0 Ų025.6 Ų25.60%015%0.145CC..Hα-helixtrans-58.8-37.8173.661.60000112.2Q96 A97 L98 E318 Y367S94-Q96 PolarHBondContact O-N 3.3Å; S94-A97 PolarHBondContact O-N 3.5Å; S94-L98 VanDerWaalsContact O-CG 3.29Å; S94-L98 WeakPolarHBondContact O-CG 3.01Å; S94-L98 PolarHBondContact O-N 3.49Å; S94-E318 WeakPolarHBondContact CB-OE1 3.37Å; S94-E318 PolarHBondContact N-OE1 2.93Å; S94-E318 PolarHBondContact N-OE2 2.98Å; S94-E318 PolarHBondContact OG-OE1 2.79Å; S94-Y367 WeakPolarHBondContact CB-OH 3.46Å; S94-Y367 WeakPolarHBondContact OG-CE2 3.49Å; S94-Y367 PolarHBondContact OG-OH 3Å
95Q98.6Very high97.4Very high25 Ų2526.8 Ų26.812%0.11715%0.15CC..Hα-helixtrans-64.6-43.5179.6-60.682.2-2.300111.3F10 S93 L98 A99 E318 Y366 Y367F10-Q95 HydrophobicContact CE2-CB 3.72Å; F10-Q95 HydrophobicContact CZ-CB 3.83Å; S93-Q95 VanDerWaalsContact C-N 3.27Å; S93-Q95 PolarHBondContact O-N 3.49Å; S93-Q95 PolarHBondContact OG-OE1 2.95Å; Q95-L98 PolarHBondContact O-N 3.06Å; Q95-A99 PolarHBondContact O-N 3.25Å; Q95-A99 VanDerWaalsContact O-N 3.13Å; Q95-E318 PolarHBondContact OE1-OE1 3.39Å; Q95-E318 VanDerWaalsContact OE1-OE1 3.09Å; Q95-Y366 HydrophobicContact CG-CD1 4.17Å; Q95-Y366 HydrophobicContact CG-CE1 3.67Å; Q95-Y367 PolarHBondContact N-OH 3.47Å
96Q98.7Very high97.6Very high8 Ų827.2 Ų27.24%0.03715%0.154CC..Hα-helixtrans-66.6-39.4177.6-69.2-78.519.700111.5D8 H9 F10 R73 S93 S94 A99 D100D8-Q96 PolarHBondContact OD1-NE2 2.74Å; H9-Q96 PolarHBondContact CD2-OE1 2.92Å; H9-Q96 VanDerWaalsContact CD2-OE1 3.25Å; F10-Q96 VanDerWaalsContact CD2-CD 3.5Å; F10-Q96 HydrophobicContact CD2-CG 4.07Å; F10-Q96 HydrophobicContact CE2-CB 4.39Å; F10-Q96 HydrophobicContact CE2-CG 3.85Å; R73-Q96 VanDerWaalsContact NH1-CB 3.31Å; S93-Q96 PolarHBondContact O-N 3.3Å; S93-Q96 WeakPolarHBondContact OG-CB 3.48Å; S93-Q96 WeakPolarHBondContact OG-CG 3.48Å; S93-Q96 PolarHBondContact OG-N 3.39Å; S94-Q96 PolarHBondContact O-N 3.3Å; Q96-A99 PolarHBondContact O-N 3.23Å; Q96-D100 PolarHBondContact O-N 3.33Å
97A98.8Very high97.8Very high5 Ų529 Ų294%0.04116%0.156CC..Hα-helixtrans-63-40.6175.600000112.3H72 R73 S93 S94 A99 D100 L101 L131H72-A97 WeakPolarHBondContact NE2-CB 3.01Å; R73-A97 HydrophobicContact CG-CB 4.35Å; S93-A97 PolarHBondContact O-N 2.97Å; S94-A97 PolarHBondContact O-N 3.5Å; A97-A99 VanDerWaalsContact C-N 3.3Å; A97-A99 PolarHBondContact O-N 2.81Å; A97-D100 WeakPolarHBondContact O-CB 3.4Å; A97-D100 PolarHBondContact O-N 3.42Å; A97-L101 WeakPolarHBondContact O-CG 3.45Å; A97-L101 PolarHBondContact O-N 2.99Å; A97-L101 VanDerWaalsContact O-N 3.16Å; A97-L131 HydrophobicContact CB-CD2 4.35Å
98L98.9Very high98Very high2 Ų222.6 Ų22.61%0.0113%0.126CC..Hα-helixtrans-64.7-34.5174.5-66.6176.8000112.4S94 Q95 L101 A102 L131 W134 F135 K138 F139 Y367S94-L98 VanDerWaalsContact O-CG 3.29Å; S94-L98 WeakPolarHBondContact O-CG 3.01Å; S94-L98 PolarHBondContact O-N 3.49Å; Q95-L98 PolarHBondContact O-N 3.06Å; L98-L101 HydrophobicContact CD2-CD1 4.05Å; L98-L101 WeakPolarHBondContact O-CB 3.47Å; L98-L101 PolarHBondContact O-N 3.21Å; L98-A102 PolarHBondContact O-N 2.82Å; L98-L131 HydrophobicContact CD2-CB 4.5Å; L98-L131 HydrophobicContact CD2-CD2 3.97Å; L98-L131 WeakPolarHBondContact CD2-O 3.45Å; L98-L131 HydrophobicContact CG-CD2 4.24Å; L98-W134 HydrophobicContact CD1-CB 3.72Å; L98-W134 HydrophobicContact CD2-CB 4.16Å; L98-F135 HydrophobicContact CD2-CB 3.82Å; L98-K138 HydrophobicContact CD1-CG 4.45Å; L98-F139 HydrophobicContact CB-CE2 3.98Å; L98-Y367 HydrophobicContact CD1-CE1 3.64Å
99A98.8Very high98.2Very high10 Ų1022.3 Ų22.38%0.08313%0.126CC..Hα-helixtrans-69.2-35.4173.500000112.2H9 F10 Q95 Q96 A97 L101 A102 V103H9-A99 HydrophobicContact CB-CB 3.66Å; H9-A99 VanDerWaalsContact CD2-CB 3.47Å; H9-A99 WeakPolarHBondContact CD2-CB 3.44Å; H9-A99 VanDerWaalsContact CG-CB 3.41Å; F10-A99 HydrophobicContact CZ-CB 4.3Å; Q95-A99 PolarHBondContact O-N 3.25Å; Q95-A99 VanDerWaalsContact O-N 3.13Å; Q96-A99 PolarHBondContact O-N 3.23Å; A97-A99 VanDerWaalsContact C-N 3.3Å; A97-A99 PolarHBondContact O-N 2.81Å; A99-L101 VanDerWaalsContact C-N 3.28Å; A99-L101 PolarHBondContact O-N 2.88Å; A99-A102 WeakPolarHBondContact O-CB 3.48Å; A99-A102 PolarHBondContact O-N 3.26Å; A99-V103 PolarHBondContact O-N 3.42Å; A99-V103 VanDerWaalsContact O-N 3.16Å
100D98.9Very high98.3Very high1 Ų128.1 Ų28.11%0.00515%0.153CC..Hα-helixtrans-58-41.9170.5-65.8-35.6000111.6Q5 H9 R73 Q96 A97 A102 V103 F104Q5-D100 PolarHBondContact NE2-O 3Å; H9-D100 IonicContact CD2-OD1 3.68Å; H9-D100 IonicContact CE1-OD1 3.68Å; H9-D100 PolarHBondContact NE2-N 2.92Å; H9-D100 IonicContact NE2-OD1 2.73Å; H9-D100 PolarHBondContact NE2-OD1 3.47Å; R73-D100 IonicContact CZ-OD1 3.32Å; R73-D100 IonicContact CZ-OD2 3.64Å; R73-D100 IonicContact NE-OD1 2.69Å; R73-D100 IonicContact NE-OD2 2.75Å; R73-D100 PolarHBondContact NE-OD2 3.49Å; R73-D100 VanDerWaalsContact NH2-CG 3.25Å; R73-D100 IonicContact NH2-OD1 3.14Å; R73-D100 PolarHBondContact NH2-OD1 3.48Å; R73-D100 IonicContact NH2-OD2 3.76Å; R73-D100 PolarHBondContact NH2-OD2 2.99Å; R73-D100 VanDerWaalsContact NH2-OD2 3.14Å; Q96-D100 PolarHBondContact O-N 3.33Å; A97-D100 WeakPolarHBondContact O-CB 3.4Å; A97-D100 PolarHBondContact O-N 3.42Å; D100-A102 VanDerWaalsContact C-N 3.29Å; D100-A102 PolarHBondContact O-N 2.84Å; D100-V103 PolarHBondContact O-N 3.4Å; D100-F104 VanDerWaalsContact O-CB 3.27Å; D100-F104 WeakPolarHBondContact O-CB 3.07Å; D100-F104 PolarHBondContact O-N 3.46Å
101L98.9Very high98.4Very high6 Ų628 Ų283%0.03115%0.148CC..Hα-helixtrans-61.4-37.5178.2-63.3177.7000112I40 V70 A97 L98 A99 F104 H105 F135I40-L101 HydrophobicContact CD1-CD1 3.65Å; I40-L101 HydrophobicContact CG1-CD1 4.07Å; I40-L101 HydrophobicContact CG1-CD2 4.06Å; I40-L101 HydrophobicContact CG2-CD1 4.18Å; I40-L101 HydrophobicContact CG2-CD2 4.25Å; V70-L101 HydrophobicContact CG1-CD2 3.45Å; V70-L101 VanDerWaalsContact CG1-CD2 3.45Å; A97-L101 WeakPolarHBondContact O-CG 3.45Å; A97-L101 PolarHBondContact O-N 2.99Å; A97-L101 VanDerWaalsContact O-N 3.16Å; L98-L101 HydrophobicContact CD2-CD1 4.05Å; L98-L101 WeakPolarHBondContact O-CB 3.47Å; L98-L101 PolarHBondContact O-N 3.21Å; A99-L101 VanDerWaalsContact C-N 3.28Å; A99-L101 PolarHBondContact O-N 2.88Å; L101-F104 PolarHBondContact O-N 2.64Å; L101-H105 VanDerWaalsContact O-CB 3.31Å; L101-H105 WeakPolarHBondContact O-CB 3.49Å; L101-H105 PolarHBondContact O-N 3.36Å; L101-F135 HydrophobicContact CB-CD1 4.48Å; L101-F135 HydrophobicContact CB-CD2 3.76Å; L101-F135 HydrophobicContact CB-CE1 4.28Å; L101-F135 HydrophobicContact CB-CE2 3.54Å; L101-F135 HydrophobicContact CB-CG 4.26Å; L101-F135 HydrophobicContact CB-CZ 3.83Å; L101-F135 HydrophobicContact CD1-CB 3.89Å; L101-F135 HydrophobicContact CD1-CD1 4.13Å; L101-F135 HydrophobicContact CD1-CD2 3.88Å; L101-F135 HydrophobicContact CD1-CE2 4.48Å; L101-F135 HydrophobicContact CD1-CG 3.71Å; L101-F135 HydrophobicContact CG-CD2 4.5Å
102A98.7Very high98.4Very high20 Ų2028.4 Ų28.417%0.16515%0.149CC..Hα-helixtrans-66-44.2176.600000112L98 A99 D100 H105 Q106 F139 L142L98-A102 PolarHBondContact O-N 2.82Å; A99-A102 WeakPolarHBondContact O-CB 3.48Å; A99-A102 PolarHBondContact O-N 3.26Å; D100-A102 VanDerWaalsContact C-N 3.29Å; D100-A102 PolarHBondContact O-N 2.84Å; A102-H105 PolarHBondContact O-N 2.92Å; A102-Q106 PolarHBondContact O-N 3.47Å; A102-Q106 VanDerWaalsContact O-N 3.16Å; A102-F139 HydrophobicContact CB-CD1 4.12Å; A102-F139 HydrophobicContact CB-CE1 3.98Å; A102-F139 HydrophobicContact CB-CZ 4.43Å; A102-L142 HydrophobicContact CB-CD1 3.62Å
103V98.6Very high98.4Very high41 Ų4135 Ų3525%0.24819%0.185CC..Hα-helixtrans-66.4-40.5174.91740000111.1A99 D100 Q106 Y107A99-V103 PolarHBondContact O-N 3.42Å; A99-V103 VanDerWaalsContact O-N 3.16Å; D100-V103 PolarHBondContact O-N 3.4Å; V103-Q106 PolarHBondContact O-N 3.49Å; V103-Y107 PolarHBondContact O-N 2.88Å
104F98.8Very high98.3Very high0 Ų035 Ų350%018%0.183CC..Hα-helixtrans-62.9-44.2176.9178.9-111.9000111.8V3 F22 L38 L68 V70 D100 L101 Q106 Y107 I108V3-F104 HydrophobicContact CG1-CD2 3.98Å; F22-F104 HydrophobicContact CB-CE2 3.68Å; F22-F104 HydrophobicContact CB-CZ 3.76Å; F22-F104 HydrophobicContact CD1-CD2 4.45Å; F22-F104 AromaticContact CD1-CE2 3.63Å; F22-F104 HydrophobicContact CD1-CE2 3.63Å; F22-F104 HydrophobicContact CD1-CZ 4.45Å; F22-F104 AromaticContact CD2-CE2 3.86Å; F22-F104 HydrophobicContact CD2-CE2 3.86Å; F22-F104 AromaticContact CD2-CZ 3.95Å; F22-F104 HydrophobicContact CD2-CZ 3.95Å; F22-F104 HydrophobicContact CE1-CE2 4.15Å; F22-F104 HydrophobicContact CE2-CE2 4.37Å; F22-F104 AromaticContact CG-CE2 3.46Å; F22-F104 HydrophobicContact CG-CE2 3.46Å; F22-F104 VanDerWaalsContact CG-CE2 3.46Å; F22-F104 AromaticContact CG-CZ 3.83Å; F22-F104 HydrophobicContact CG-CZ 3.83Å; L38-F104 HydrophobicContact CD1-CD1 4.21Å; L38-F104 HydrophobicContact CD1-CE1 3.7Å; L68-F104 HydrophobicContact CB-CE1 4.45Å; L68-F104 HydrophobicContact CD1-CE1 4.35Å; V70-F104 HydrophobicContact CB-CD1 3.9Å; V70-F104 HydrophobicContact CB-CE1 3.73Å; V70-F104 HydrophobicContact CB-CG 4.37Å; V70-F104 HydrophobicContact CB-CZ 4.06Å; V70-F104 HydrophobicContact CG1-CD1 4.12Å; V70-F104 HydrophobicContact CG1-CE1 4.21Å; V70-F104 HydrophobicContact CG2-CD1 3.95Å; V70-F104 HydrophobicContact CG2-CD2 4.1Å; V70-F104 HydrophobicContact CG2-CE1 4.14Å; V70-F104 HydrophobicContact CG2-CE2 4.28Å; V70-F104 HydrophobicContact CG2-CG 3.91Å; V70-F104 HydrophobicContact CG2-CZ 4.29Å; D100-F104 VanDerWaalsContact O-CB 3.27Å; D100-F104 WeakPolarHBondContact O-CB 3.07Å; D100-F104 PolarHBondContact O-N 3.46Å; L101-F104 PolarHBondContact O-N 2.64Å; F104-Q106 VanDerWaalsContact C-N 3.31Å; F104-Q106 PolarHBondContact O-N 2.73Å; F104-Y107 PolarHBondContact O-N 2.8Å; F104-I108 HydrophobicContact CD1-CG1 4.33Å; F104-I108 HydrophobicContact CD2-CG1 4.03Å; F104-I108 HydrophobicContact CE1-CG1 3.86Å; F104-I108 HydrophobicContact CE2-CD1 3.73Å; F104-I108 HydrophobicContact CE2-CG1 3.52Å; F104-I108 HydrophobicContact CG-CG1 4.42Å; F104-I108 HydrophobicContact CZ-CD1 3.74Å; F104-I108 HydrophobicContact CZ-CG1 3.44Å; F104-I108 VanDerWaalsContact CZ-CG1 3.44Å; F104-I108 WeakPolarHBondContact O-CG1 3.37Å; F104-I108 PolarHBondContact O-N 2.86Å
105H98.8Very high98.1Very high26 Ų2637 Ų3712%0.1220%0.197CC..Hα-helixtrans-55.1-47173.6170.2-77.6000111.2L101 A102 S109 W120 L142L101-H105 VanDerWaalsContact O-CB 3.31Å; L101-H105 WeakPolarHBondContact O-CB 3.49Å; L101-H105 PolarHBondContact O-N 3.36Å; A102-H105 PolarHBondContact O-N 2.92Å; H105-S109 PolarHBondContact CE1-OG 3.43Å; H105-S109 VanDerWaalsContact O-CB 3.28Å; H105-S109 WeakPolarHBondContact O-CB 3.23Å; H105-S109 PolarHBondContact O-N 3.25Å; H105-S109 PolarHBondContact O-OG 3.19Å; H105-W120 AromaticContact CD2-CD2 3.49Å; H105-W120 VanDerWaalsContact CD2-CD2 3.49Å; H105-W120 AromaticContact CD2-CE2 3.35Å; H105-W120 AromaticContact CD2-CE3 3.82Å; H105-W120 AromaticContact CD2-CG 3.99Å; H105-W120 AromaticContact CD2-CH2 3.89Å; H105-W120 AromaticContact CD2-CZ2 3.56Å; H105-W120 AromaticContact CD2-NE1 3.77Å; H105-W120 AromaticContact NE2-CD1 3.64Å; H105-W120 AromaticContact NE2-CD2 3.82Å; H105-W120 AromaticContact NE2-CE2 3.41Å; H105-W120 AromaticContact NE2-CG 3.95Å; H105-W120 AromaticContact NE2-CZ2 3.86Å; H105-W120 AromaticContact NE2-NE1 3.3Å; H105-W120 PolarHBondContact NE2-NE1 2.82Å; H105-L142 PolarHBondContact CD2-O 3.43Å; H105-L142 PolarHBondContact NE2-O 3.35Å
106Q98.4Very high97.7Very high111 Ų11140.3 Ų40.352%0.51922%0.223SC..Hα-helixtrans-61.8-47.2177.2-178.5178.9-400111.8A102 V103 F104 I108 S109 Q110A102-Q106 PolarHBondContact O-N 3.47Å; A102-Q106 VanDerWaalsContact O-N 3.16Å; V103-Q106 PolarHBondContact O-N 3.49Å; F104-Q106 VanDerWaalsContact C-N 3.31Å; F104-Q106 PolarHBondContact O-N 2.73Å; Q106-I108 PolarHBondContact O-N 3.43Å; Q106-S109 PolarHBondContact O-N 3.16Å; Q106-Q110 WeakPolarHBondContact O-CG 3.4Å; Q106-Q110 PolarHBondContact O-N 2.81Å
107Y98.6Very high97.3Very high85 Ų8546.4 Ų46.433%0.33325%0.246SC..Hα-helixtrans-58.5-46.8179.1172.3-96.4000112.1V3 F22 V103 F104 Q110 S111V3-Y107 HydrophobicContact CB-CD1 4.1Å; V3-Y107 HydrophobicContact CB-CE1 4.29Å; V3-Y107 HydrophobicContact CB-CG 4.29Å; V3-Y107 HydrophobicContact CG2-CD1 3.87Å; V3-Y107 HydrophobicContact CG2-CD2 3.82Å; V3-Y107 HydrophobicContact CG2-CE1 4.39Å; V3-Y107 HydrophobicContact CG2-CE2 4.34Å; V3-Y107 HydrophobicContact CG2-CG 3.55Å; F22-Y107 AromaticContact CE1-CE1 3.86Å; F22-Y107 HydrophobicContact CE1-CE1 3.86Å; F22-Y107 AromaticContact CZ-CE1 3.72Å; F22-Y107 HydrophobicContact CZ-CE1 3.72Å; V103-Y107 PolarHBondContact O-N 2.88Å; F104-Y107 PolarHBondContact O-N 2.8Å; Y107-Q110 PolarHBondContact O-N 2.84Å; Y107-S111 VanDerWaalsContact O-CB 3.3Å; Y107-S111 WeakPolarHBondContact O-CB 3.5Å; Y107-S111 PolarHBondContact O-N 3.41Å; Y107-S111 PolarHBondContact O-OG 2.78Å
108I98.5Very high97.3Very high0 Ų046.5 Ų46.50%025%0.245CC..Hα-helixtrans-67.5-41.4178-68-63.9000111.2F22 L68 F104 Q106 Q110 S111 F112 L114 W120F22-I108 HydrophobicContact CD2-CD1 4.36Å; F22-I108 HydrophobicContact CE2-CD1 3.9Å; F22-I108 HydrophobicContact CZ-CD1 4.27Å; L68-I108 HydrophobicContact CD1-CB 4.47Å; L68-I108 HydrophobicContact CD1-CG1 4.28Å; L68-I108 HydrophobicContact CD1-CG2 3.73Å; L68-I108 HydrophobicContact CD2-CD1 4.12Å; L68-I108 HydrophobicContact CD2-CG1 4.49Å; L68-I108 HydrophobicContact CD2-CG2 4.29Å; F104-I108 HydrophobicContact CD1-CG1 4.33Å; F104-I108 HydrophobicContact CD2-CG1 4.03Å; F104-I108 HydrophobicContact CE1-CG1 3.86Å; F104-I108 HydrophobicContact CE2-CD1 3.73Å; F104-I108 HydrophobicContact CE2-CG1 3.52Å; F104-I108 HydrophobicContact CG-CG1 4.42Å; F104-I108 HydrophobicContact CZ-CD1 3.74Å; F104-I108 HydrophobicContact CZ-CG1 3.44Å; F104-I108 VanDerWaalsContact CZ-CG1 3.44Å; F104-I108 WeakPolarHBondContact O-CG1 3.37Å; F104-I108 PolarHBondContact O-N 2.86Å; Q106-I108 PolarHBondContact O-N 3.43Å; I108-Q110 VanDerWaalsContact C-N 3.27Å; I108-Q110 PolarHBondContact O-N 3.37Å; I108-S111 PolarHBondContact O-N 2.83Å; I108-F112 HydrophobicContact CD1-CD2 4.32Å; I108-F112 HydrophobicContact CD1-CE2 4.01Å; I108-F112 HydrophobicContact CG2-CD2 3.87Å; I108-F112 HydrophobicContact CG2-CE2 4.46Å; I108-F112 WeakPolarHBondContact O-CB 3.43Å; I108-F112 WeakPolarHBondContact O-CD2 3.29Å; I108-F112 PolarHBondContact O-N 3.36Å; I108-L114 HydrophobicContact CG2-CD1 3.89Å; I108-W120 HydrophobicContact CB-CH2 3.94Å; I108-W120 HydrophobicContact CB-CZ2 4.48Å; I108-W120 HydrophobicContact CG2-CH2 3.67Å; I108-W120 HydrophobicContact CG2-CZ2 4.07Å
109S98.3Very high97.2Very high21 Ų2147 Ų4715%0.14725%0.248CC..Hα-helixtrans-58.1-42177.8-62.70000111.9H105 Q106 N113 L114H105-S109 PolarHBondContact CE1-OG 3.43Å; H105-S109 VanDerWaalsContact O-CB 3.28Å; H105-S109 WeakPolarHBondContact O-CB 3.23Å; H105-S109 PolarHBondContact O-N 3.25Å; H105-S109 PolarHBondContact O-OG 3.19Å; Q106-S109 PolarHBondContact O-N 3.16Å; S109-N113 CarbonylContact O-C 3.5Å; S109-N113 WeakPolarHBondContact O-CA 3.46Å; S109-N113 PolarHBondContact O-N 3.17Å; S109-N113 VanDerWaalsContact O-N 3.12Å; S109-L114 PolarHBondContact O-N 2.7Å
110Q97.9Very high97.2Very high122 Ų12247 Ų4757%0.5725%0.246SC*.Hα-helixtrans-69.9-45.2174.6-68.1174.2-7.700112.1Q106 Y107 I108 F112 N113Q106-Q110 WeakPolarHBondContact O-CG 3.4Å; Q106-Q110 PolarHBondContact O-N 2.81Å; Y107-Q110 PolarHBondContact O-N 2.84Å; I108-Q110 VanDerWaalsContact C-N 3.27Å; I108-Q110 PolarHBondContact O-N 3.37Å; Q110-F112 VanDerWaalsContact C-N 3.27Å; Q110-F112 PolarHBondContact O-N 3.42Å; Q110-N113 PolarHBondContact O-N 3.31Å; Q110-N113 PolarHBondContact O-OD1 2.87Å
111S97.2Very high97.2Very high61 Ų6147 Ų4743%0.42725%0.246SC..Hα-helixtrans-65.1-30.4-175.7-600000113.2Y107 I108Y107-S111 VanDerWaalsContact O-CB 3.3Å; Y107-S111 WeakPolarHBondContact O-CB 3.5Å; Y107-S111 PolarHBondContact O-N 3.41Å; Y107-S111 PolarHBondContact O-OG 2.78Å; I108-S111 PolarHBondContact O-N 2.83Å
112F97.1Very high97.2Very high32 Ų3246.7 Ų46.714%0.1425%0.245CC..THydrogen-bonded Turntrans-110.17.8-177.2-71.2-90.5000113.7V24 E26 W29 L66 I108 Q110 L114V24-F112 HydrophobicContact CG1-CE1 4.35Å; V24-F112 HydrophobicContact CG1-CZ 3.85Å; V24-F112 HydrophobicContact CG2-CZ 4.37Å; E26-F112 HydrophobicContact CG-CE1 4.18Å; W29-F112 HydrophobicContact CH2-CB 4.08Å; W29-F112 HydrophobicContact CH2-CD1 4.32Å; W29-F112 HydrophobicContact CZ3-CB 4.35Å; W29-F112 AromaticContact CZ3-CD1 3.74Å; W29-F112 HydrophobicContact CZ3-CD1 3.74Å; W29-F112 HydrophobicContact CZ3-CG 4.49Å; L66-F112 HydrophobicContact CD2-CD1 4.32Å; L66-F112 HydrophobicContact CD2-CG 4.23Å; I108-F112 HydrophobicContact CD1-CD2 4.32Å; I108-F112 HydrophobicContact CD1-CE2 4.01Å; I108-F112 HydrophobicContact CG2-CD2 3.87Å; I108-F112 HydrophobicContact CG2-CE2 4.46Å; I108-F112 WeakPolarHBondContact O-CB 3.43Å; I108-F112 WeakPolarHBondContact O-CD2 3.29Å; I108-F112 PolarHBondContact O-N 3.36Å; Q110-F112 VanDerWaalsContact C-N 3.27Å; Q110-F112 PolarHBondContact O-N 3.42Å; F112-L114 HydrophobicContact CB-CD1 4.33Å; F112-L114 HydrophobicContact CB-CD2 3.83Å; F112-L114 HydrophobicContact CB-CG 3.82Å; F112-L114 PolarHBondContact O-N 3.5Å
113N96.8Very high97.2Very high140 Ų14046 Ų4675%0.74924%0.238SC*.THydrogen-bonded Turntrans51.941-175.5-65.9-28.6000113.1S109 Q110S109-N113 CarbonylContact O-C 3.5Å; S109-N113 WeakPolarHBondContact O-CA 3.46Å; S109-N113 PolarHBondContact O-N 3.17Å; S109-N113 VanDerWaalsContact O-N 3.12Å; Q110-N113 PolarHBondContact O-N 3.31Å; Q110-N113 PolarHBondContact O-OD1 2.87Å
114L97.1Very high97.2Very high19 Ų1944 Ų4410%0.09923%0.226CC..  trans-75148.3177.2-48.3177.9000109.9W29 V36 L66 I108 S109 F112 N118 W120W29-L114 HydrophobicContact CH2-CD2 3.63Å; W29-L114 HydrophobicContact CZ2-CD2 3.39Å; V36-L114 HydrophobicContact CG2-CD1 3.77Å; L66-L114 HydrophobicContact CD2-CD1 4.33Å; L66-L114 HydrophobicContact CD2-CD2 4.5Å; I108-L114 HydrophobicContact CG2-CD1 3.89Å; S109-L114 PolarHBondContact O-N 2.7Å; F112-L114 HydrophobicContact CB-CD1 4.33Å; F112-L114 HydrophobicContact CB-CD2 3.83Å; F112-L114 HydrophobicContact CB-CG 3.82Å; F112-L114 PolarHBondContact O-N 3.5Å; L114-N118 WeakPolarHBondContact CA-OD1 3.18Å; L114-N118 HydrophobicContact CB-CB 4.29Å; L114-N118 HydrophobicContact CD2-CB 4.47Å; L114-W120 HydrophobicContact CD1-CH2 4.43Å; L114-W120 HydrophobicContact CD1-CZ2 3.56Å
115S93.4Very high97.2Very high42 Ų4244.6 Ų44.629%0.29423%0.232SC..  trans-132.2-176.2-179.967.10000110.5R117 N118S115-R117 PolarHBondContact O-N 2.87Å; S115-R117 PolarHBondContact OG-N 3.18Å; S115-N118 PolarHBondContact N-OD1 3.15Å; S115-N118 PolarHBondContact O-N 3.11Å; S115-N118 PolarHBondContact O-OD1 3.08Å
116S90.4Very high97.2Very high94 Ų9444.1 Ų44.166%0.65723%0.232SC*.THydrogen-bonded Turntrans-55.8-15.6171.557.90000113.3K447S116-K447 WeakPolarHBondContact O-CD 3.39Å; S116-K447 WeakPolarHBondContact O-CE 3.31Å; S116-K447 PolarHBondContact O-NZ 2.64Å
117R91.6Very high97.2Very high137 Ų13739 Ų3952%0.51721%0.208SC..THydrogen-bonded Turntrans-68.2-31.4173.4-61.5-166.6-58-82.4-3.8113.1D33 S115 T119 K447D33-R117 IonicContact OD1-CZ 3.67Å; D33-R117 IonicContact OD1-NE 3.83Å; D33-R117 PolarHBondContact OD1-NE 3.25Å; D33-R117 IonicContact OD1-NH2 2.71Å; D33-R117 PolarHBondContact OD1-NH2 2.98Å; S115-R117 PolarHBondContact O-N 2.87Å; S115-R117 PolarHBondContact OG-N 3.18Å; R117-T119 PolarHBondContact O-N 3.04Å; R117-K447 VanDerWaalsContact C-NZ 3.33Å; R117-K447 PolarHBondContact O-NZ 3.43Å
118N97.1Very high97.2Very high7 Ų735.2 Ų35.24%0.03719%0.193CC..SBendtrans-82.3111.3-179.2-54.692.1000110.4P32 G34 V36 L114 S115P32-N118 PolarHBondContact O-ND2 3.12Å; G34-N118 PolarHBondContact O-ND2 2.93Å; V36-N118 HydrophobicContact CG2-CB 4.21Å; L114-N118 WeakPolarHBondContact CA-OD1 3.18Å; L114-N118 HydrophobicContact CB-CB 4.29Å; L114-N118 HydrophobicContact CD2-CB 4.47Å; S115-N118 PolarHBondContact N-OD1 3.15Å; S115-N118 PolarHBondContact O-N 3.11Å; S115-N118 PolarHBondContact O-OD1 3.08Å
119T98Very high97.2Very high12 Ų1235.2 Ų35.27%0.07419%0.193CC..  trans-80.2124.8176.5-540000110.1P35 V36 R117 I121 Y144 L440 A443 K447P35-T119 CarbonylContact C-O 3.59Å; P35-T119 VanDerWaalsContact CA-O 3.29Å; P35-T119 WeakPolarHBondContact CA-O 3.47Å; P35-T119 WeakPolarHBondContact CB-O 3.36Å; V36-T119 PolarHBondContact N-O 2.87Å; R117-T119 PolarHBondContact O-N 3.04Å; T119-I121 HydrophobicContact CG2-CD1 4.31Å; T119-Y144 HydrophobicContact CG2-CD1 3.98Å; T119-Y144 HydrophobicContact CG2-CD2 4.24Å; T119-Y144 HydrophobicContact CG2-CG 3.65Å; T119-L440 HydrophobicContact CG2-CD2 3.82Å; T119-A443 HydrophobicContact CG2-CB 3.63Å; T119-A443 WeakPolarHBondContact OG1-CB 3.33Å; T119-K447 PolarHBondContact OG1-NZ 3.42Å
120W98.8Very high97.2Very high11 Ų1134.2 Ų34.24%0.04219%0.187CC..EExtended strand (participates in β ladder)trans-93.2131.5177.1-73.775.3000111.7V36 L38 L68 H105 I108 L114 V143 Y144V36-W120 HydrophobicContact CB-CD2 3.6Å; V36-W120 HydrophobicContact CB-CE3 3.87Å; V36-W120 HydrophobicContact CB-CG 3.96Å; V36-W120 HydrophobicContact CB-CZ2 4.35Å; V36-W120 HydrophobicContact CB-CZ3 4.34Å; V36-W120 HydrophobicContact CG1-CD2 3.71Å; V36-W120 HydrophobicContact CG1-CE3 3.46Å; V36-W120 VanDerWaalsContact CG1-CE3 3.46Å; V36-W120 HydrophobicContact CG1-CH2 3.79Å; V36-W120 HydrophobicContact CG1-CZ2 4.02Å; V36-W120 HydrophobicContact CG1-CZ3 3.5Å; V36-W120 HydrophobicContact CG2-CD2 4.09Å; V36-W120 HydrophobicContact CG2-CG 4.42Å; V36-W120 HydrophobicContact CG2-CZ2 4.18Å; V36-W120 CarbonylContact O-C 3.47Å; V36-W120 WeakPolarHBondContact O-CA 3.28Å; L38-W120 HydrophobicContact CB-CE3 4.32Å; L38-W120 HydrophobicContact CB-CZ3 4.4Å; L38-W120 HydrophobicContact CD2-CZ3 4.33Å; L68-W120 HydrophobicContact CD1-CH2 3.64Å; L68-W120 HydrophobicContact CD1-CZ3 3.56Å; H105-W120 AromaticContact CD2-CD2 3.49Å; H105-W120 VanDerWaalsContact CD2-CD2 3.49Å; H105-W120 AromaticContact CD2-CE2 3.35Å; H105-W120 AromaticContact CD2-CE3 3.82Å; H105-W120 AromaticContact CD2-CG 3.99Å; H105-W120 AromaticContact CD2-CH2 3.89Å; H105-W120 AromaticContact CD2-CZ2 3.56Å; H105-W120 AromaticContact CD2-NE1 3.77Å; H105-W120 AromaticContact NE2-CD1 3.64Å; H105-W120 AromaticContact NE2-CD2 3.82Å; H105-W120 AromaticContact NE2-CE2 3.41Å; H105-W120 AromaticContact NE2-CG 3.95Å; H105-W120 AromaticContact NE2-CZ2 3.86Å; H105-W120 AromaticContact NE2-NE1 3.3Å; H105-W120 PolarHBondContact NE2-NE1 2.82Å; I108-W120 HydrophobicContact CB-CH2 3.94Å; I108-W120 HydrophobicContact CB-CZ2 4.48Å; I108-W120 HydrophobicContact CG2-CH2 3.67Å; I108-W120 HydrophobicContact CG2-CZ2 4.07Å; L114-W120 HydrophobicContact CD1-CH2 4.43Å; L114-W120 HydrophobicContact CD1-CZ2 3.56Å; W120-V143 HydrophobicContact CB-CG2 4.28Å; W120-Y144 WeakPolarHBondContact O-CA 3.31Å; W120-Y144 VanDerWaalsContact O-CB 3.29Å; W120-Y144 WeakPolarHBondContact O-CB 3.37Å; W120-Y144 PolarHBondContact O-N 2.96Å
121I98.8Very high97.3Very high0 Ų028.5 Ų28.50%016%0.16CC..EExtended strand (participates in β ladder)trans-125.3130171.2-53.4-65.2000108.3V36 F37 L38 T119 F123 Y144 G145 W439 L440V36-I121 PolarHBondContact O-N 3.24Å; F37-I121 WeakPolarHBondContact CA-O 3.12Å; F37-I121 HydrophobicContact CD1-CB 4.06Å; F37-I121 HydrophobicContact CD1-CG1 4.36Å; F37-I121 HydrophobicContact CE1-CB 4.11Å; F37-I121 HydrophobicContact CE1-CG1 4Å; L38-I121 PolarHBondContact N-O 2.89Å; T119-I121 HydrophobicContact CG2-CD1 4.31Å; I121-F123 HydrophobicContact CB-CE2 3.9Å; I121-F123 HydrophobicContact CB-CZ 4.18Å; I121-F123 HydrophobicContact CG2-CD2 4.41Å; I121-F123 HydrophobicContact CG2-CE1 4.3Å; I121-F123 HydrophobicContact CG2-CE2 3.6Å; I121-F123 HydrophobicContact CG2-CZ 3.54Å; I121-Y144 HydrophobicContact CD1-CD1 4.2Å; I121-G145 VanDerWaalsContact CA-O 3.31Å; I121-G145 WeakPolarHBondContact CA-O 3.46Å; I121-W439 HydrophobicContact CD1-CB 4.45Å; I121-W439 HydrophobicContact CD1-CE3 4.27Å; I121-L440 HydrophobicContact CD1-CD2 4.47Å; I121-L440 HydrophobicContact CG1-CD2 4.08Å
122S98.8Very high97.3Very high0 Ų025.6 Ų25.60%014%0.14CC..EExtended strand (participates in β ladder)trans-98.2149.1176.360.10000112.4L38 S132 G145 A146 V147L38-S122 CarbonylContact O-C 3.35Å; L38-S122 VanDerWaalsContact O-CA 3.27Å; L38-S122 WeakPolarHBondContact O-CA 3.36Å; S122-S132 WeakPolarHBondContact CB-OG 3.29Å; S122-S132 PolarHBondContact O-OG 3.03Å; S122-S132 PolarHBondContact OG-OG 3.29Å; S122-G145 PolarHBondContact N-O 2.99Å; S122-A146 CarbonylContact O-C 3.39Å; S122-A146 WeakPolarHBondContact O-CA 3.32Å; S122-A146 WeakPolarHBondContact OG-CB 3.42Å; S122-V147 PolarHBondContact O-N 2.83Å
123F98.9Very high97.4Very high4 Ų424.1 Ų24.12%0.01813%0.133CC..EExtended strand (participates in β ladder)trans-133.2143.4-179.4-59.8-94.7000109.3F37 L38 I40 H56 M59 I121 S132 V147 M414 V436F37-F123 HydrophobicContact CB-CD2 4.26Å; F37-F123 HydrophobicContact CB-CE2 3.7Å; F37-F123 AromaticContact CD1-CE2 3.97Å; F37-F123 HydrophobicContact CD1-CE2 3.97Å; F37-F123 HydrophobicContact CD1-CZ 4.38Å; F37-F123 AromaticContact CD2-CE2 3.55Å; F37-F123 HydrophobicContact CD2-CE2 3.55Å; F37-F123 AromaticContact CD2-CZ 3.66Å; F37-F123 HydrophobicContact CD2-CZ 3.66Å; F37-F123 HydrophobicContact CE1-CE2 4.5Å; F37-F123 HydrophobicContact CE1-CZ 4.49Å; F37-F123 HydrophobicContact CE2-CE2 4.14Å; F37-F123 AromaticContact CE2-CZ 3.79Å; F37-F123 HydrophobicContact CE2-CZ 3.79Å; F37-F123 HydrophobicContact CG-CD2 4.47Å; F37-F123 AromaticContact CG-CE2 3.47Å; F37-F123 HydrophobicContact CG-CE2 3.47Å; F37-F123 VanDerWaalsContact CG-CE2 3.47Å; F37-F123 AromaticContact CG-CZ 4Å; F37-F123 HydrophobicContact CG-CZ 4Å; F37-F123 HydrophobicContact CZ-CZ 4.22Å; L38-F123 PolarHBondContact O-N 3.42Å; I40-F123 PolarHBondContact N-O 2.86Å; H56-F123 HydrophobicContact CB-CB 4.27Å; H56-F123 HydrophobicContact CB-CD1 3.76Å; H56-F123 HydrophobicContact CB-CD2 4.19Å; H56-F123 HydrophobicContact CB-CE1 4.13Å; H56-F123 HydrophobicContact CB-CG 3.8Å; H56-F123 HydrophobicContact CB-CZ 4.5Å; M59-F123 HydrophobicContact CE-CD1 4.39Å; M59-F123 HydrophobicContact CE-CE1 3.62Å; M59-F123 HydrophobicContact CE-CZ 4.35Å; I121-F123 HydrophobicContact CB-CE2 3.9Å; I121-F123 HydrophobicContact CB-CZ 4.18Å; I121-F123 HydrophobicContact CG2-CD2 4.41Å; I121-F123 HydrophobicContact CG2-CE1 4.3Å; I121-F123 HydrophobicContact CG2-CE2 3.6Å; I121-F123 HydrophobicContact CG2-CZ 3.54Å; F123-S132 PolarHBondContact N-OG 3.11Å; F123-V147 WeakPolarHBondContact CA-O 3.23Å; F123-V147 HydrophobicContact CD1-CB 3.7Å; F123-V147 HydrophobicContact CD1-CG1 4.39Å; F123-V147 HydrophobicContact CD1-CG2 3.88Å; F123-V147 HydrophobicContact CE1-CB 3.99Å; F123-V147 HydrophobicContact CE1-CG2 3.61Å; F123-V147 HydrophobicContact CZ-CG2 4.48Å; F123-M414 HydrophobicContact CB-CE 4.46Å; F123-V436 HydrophobicContact CE1-CG2 4.39Å
124G98.6Very high97.4Very high0 Ų017.8 Ų17.80%010%0.099CC..EExtended strand (participates in β ladder)trans-169.5155.8173.900000112.4S128 G129 V147 S149G124-S128 WeakPolarHBondContact CA-OG 3.14Å; G124-G129 VanDerWaalsContact C-N 3.27Å; G124-G129 VanDerWaalsContact O-CA 3.24Å; G124-G129 WeakPolarHBondContact O-CA 3.49Å; G124-V147 PolarHBondContact N-O 2.78Å; G124-S149 PolarHBondContact O-N 2.75Å
125G98.3Very high97.5Very high13 Ų1316.9 Ų16.913%0.1349%0.094CC..EExtended strand (participates in β ladder)trans-120144.9177.900000110.9Y127 S128 G129 S149 C411 M414G125-Y127 PolarHBondContact O-N 3.06Å; G125-S128 PolarHBondContact N-OG 2.75Å; G125-S128 WeakPolarHBondContact O-CA 3.5Å; G125-S128 WeakPolarHBondContact O-CB 3.44Å; G125-S128 PolarHBondContact O-N 3.4Å; G125-G129 VanDerWaalsContact C-N 3.33Å; G125-G129 PolarHBondContact O-N 3.49Å; G125-G129 VanDerWaalsContact O-N 3.16Å; G125-S149 CarbonylContact C-O 3.58Å; G125-S149 VanDerWaalsContact CA-O 3.29Å; G125-S149 WeakPolarHBondContact CA-O 3.44Å; G125-C411 WeakPolarHBondContact CA-SG 3.5Å; G125-M414 WeakPolarHBondContact CA-SD 3.36Å; G125-M414 PolarHBondContact N-SD 2.93Å; G125-M414 VanDerWaalsContact N-SD 3.35Å
126S98.3Very high97.7Very high16 Ų1615.7 Ų15.711%0.1128%0.083CC..THydrogen-bonded Turntrans59-134.4179.9-155.60000111.8S128 G129 S130 S149 S150 P152 H410 C411S126-S128 PolarHBondContact O-N 3.11Å; S126-G129 CarbonylContact O-C 3.58Å; S126-G129 VanDerWaalsContact O-CA 3.26Å; S126-G129 WeakPolarHBondContact O-CA 3.41Å; S126-G129 PolarHBondContact O-N 2.72Å; S126-S130 PolarHBondContact O-N 3.3Å; S126-S149 PolarHBondContact N-O 2.99Å; S126-S150 WeakPolarHBondContact CA-O 3.22Å; S126-P152 WeakPolarHBondContact O-CD 3.29Å; S126-H410 WeakPolarHBondContact CB-NE2 3.21Å; S126-H410 PolarHBondContact OG-NE2 3.27Å; S126-C411 PolarHBondContact N-SG 3.08Å
127Y98.8Very high97.9Very high3 Ų312.9 Ų12.91%0.0127%0.069CC..Hα-helixtrans-54.7-36.2172.8167.5-121.4000113E43 H72 G125 G129 S130 L131 W134 W311 Q314 F319E43-Y127 HydrophobicContact CB-CD1 4.29Å; E43-Y127 WeakPolarHBondContact OE2-CB 3.43Å; H72-Y127 AromaticContact CD2-CE1 3.69Å; H72-Y127 AromaticContact NE2-CE1 3.5Å; H72-Y127 WeakPolarHBondContact NE2-CE1 3.48Å; H72-Y127 AromaticContact NE2-CZ 3.51Å; H72-Y127 PolarHBondContact NE2-OH 3.13Å; G125-Y127 PolarHBondContact O-N 3.06Å; Y127-G129 VanDerWaalsContact C-N 3.27Å; Y127-G129 PolarHBondContact O-N 2.88Å; Y127-S130 WeakPolarHBondContact O-CB 3.32Å; Y127-S130 PolarHBondContact O-N 3.25Å; Y127-S130 VanDerWaalsContact O-N 3.12Å; Y127-L131 HydrophobicContact CD1-CD1 4.28Å; Y127-L131 HydrophobicContact CD2-CG 4.37Å; Y127-L131 HydrophobicContact CE1-CD1 3.72Å; Y127-L131 HydrophobicContact CE1-CG 4.36Å; Y127-L131 HydrophobicContact CE2-CD1 4.12Å; Y127-L131 HydrophobicContact CE2-CD2 4.05Å; Y127-L131 HydrophobicContact CE2-CG 3.85Å; Y127-L131 PolarHBondContact O-N 3.44Å; Y127-W134 HydrophobicContact CD2-CZ3 4.49Å; Y127-W134 HydrophobicContact CE2-CZ3 4.05Å; Y127-W311 HydrophobicContact CD1-CH2 4.49Å; Y127-W311 AromaticContact CD1-CZ3 3.82Å; Y127-W311 HydrophobicContact CD1-CZ3 3.82Å; Y127-W311 HydrophobicContact CD2-CH2 4.4Å; Y127-W311 HydrophobicContact CD2-CZ3 4.23Å; Y127-W311 HydrophobicContact CE1-CZ3 4.34Å; Y127-W311 HydrophobicContact CG-CH2 4Å; Y127-W311 AromaticContact CG-CZ3 3.75Å; Y127-W311 HydrophobicContact CG-CZ3 3.75Å; Y127-Q314 PolarHBondContact OH-NE2 2.82Å; Y127-Q314 VanDerWaalsContact OH-NE2 3.11Å; Y127-F319 HydrophobicContact CD2-CE2 4.03Å; Y127-F319 HydrophobicContact CD2-CZ 4.01Å; Y127-F319 HydrophobicContact CE2-CE1 4.46Å; Y127-F319 AromaticContact CE2-CE2 3.7Å; Y127-F319 HydrophobicContact CE2-CE2 3.7Å; Y127-F319 AromaticContact CE2-CZ 3.45Å; Y127-F319 HydrophobicContact CE2-CZ 3.45Å; Y127-F319 VanDerWaalsContact CE2-CZ 3.45Å
128S98.6Very high98.2Very high5 Ų510.2 Ų10.24%0.0356%0.061CC..Hα-helixtrans-62.8-34.2171.8145.70000112.2I40 G124 G125 S126 L131 S132I40-S128 VanDerWaalsContact O-CB 3.24Å; I40-S128 WeakPolarHBondContact O-CB 3.25Å; I40-S128 PolarHBondContact O-OG 3.21Å; G124-S128 WeakPolarHBondContact CA-OG 3.14Å; G125-S128 PolarHBondContact N-OG 2.75Å; G125-S128 WeakPolarHBondContact O-CA 3.5Å; G125-S128 WeakPolarHBondContact O-CB 3.44Å; G125-S128 PolarHBondContact O-N 3.4Å; S126-S128 PolarHBondContact O-N 3.11Å; S128-L131 PolarHBondContact O-N 2.98Å; S128-S132 PolarHBondContact O-N 3.23Å
129G98.6Very high98.2Very high0 Ų012.5 Ų12.50%07%0.071CC..Hα-helixtrans-64.1-42.6170.400000112.1G124 G125 S126 Y127 L131 S132 A133 A148 A151G124-G129 VanDerWaalsContact C-N 3.27Å; G124-G129 VanDerWaalsContact O-CA 3.24Å; G124-G129 WeakPolarHBondContact O-CA 3.49Å; G125-G129 VanDerWaalsContact C-N 3.33Å; G125-G129 PolarHBondContact O-N 3.49Å; G125-G129 VanDerWaalsContact O-N 3.16Å; S126-G129 CarbonylContact O-C 3.58Å; S126-G129 VanDerWaalsContact O-CA 3.26Å; S126-G129 WeakPolarHBondContact O-CA 3.41Å; S126-G129 PolarHBondContact O-N 2.72Å; Y127-G129 VanDerWaalsContact C-N 3.27Å; Y127-G129 PolarHBondContact O-N 2.88Å; G129-L131 VanDerWaalsContact C-N 3.34Å; G129-L131 PolarHBondContact O-N 3.25Å; G129-S132 WeakPolarHBondContact O-CB 3.23Å; G129-S132 PolarHBondContact O-N 2.81Å; G129-A133 PolarHBondContact O-N 2.75Å; G129-A148 WeakPolarHBondContact O-CB 3.18Å; G129-A151 VanDerWaalsContact C-CB 3.47Å
130S98.6Very high98.1Very high1 Ų115.1 Ų15.11%0.0079%0.088CC..Hα-helixtrans-59.7-44.6173.3-590000111.2S126 Y127 S132 A133 W134 P152S126-S130 PolarHBondContact O-N 3.3Å; Y127-S130 WeakPolarHBondContact O-CB 3.32Å; Y127-S130 PolarHBondContact O-N 3.25Å; Y127-S130 VanDerWaalsContact O-N 3.12Å; S130-S132 VanDerWaalsContact C-N 3.35Å; S130-S132 PolarHBondContact O-N 3.1Å; S130-A133 PolarHBondContact O-N 3.02Å; S130-W134 WeakPolarHBondContact O-CB 3.5Å; S130-W134 PolarHBondContact O-N 3.01Å; S130-P152 WeakPolarHBondContact OG-CD 3.34Å; S130-P152 PolarHBondContact OG-O 2.85Å
131L98.9Very high97.9Very high2 Ų220.8 Ų20.81%0.0112%0.119CC..Hα-helixtrans-61.3-39.8174.1-69.4170.3000112.6I40 H72 A97 L98 Y127 S128 G129 W134 F135I40-L131 HydrophobicContact CG2-CB 3.89Å; I40-L131 HydrophobicContact CG2-CD1 4.03Å; H72-L131 VanDerWaalsContact CD2-CD1 3.43Å; H72-L131 WeakPolarHBondContact CD2-CD1 3.17Å; A97-L131 HydrophobicContact CB-CD2 4.35Å; L98-L131 HydrophobicContact CD2-CB 4.5Å; L98-L131 HydrophobicContact CD2-CD2 3.97Å; L98-L131 WeakPolarHBondContact CD2-O 3.45Å; L98-L131 HydrophobicContact CG-CD2 4.24Å; Y127-L131 HydrophobicContact CD1-CD1 4.28Å; Y127-L131 HydrophobicContact CD2-CG 4.37Å; Y127-L131 HydrophobicContact CE1-CD1 3.72Å; Y127-L131 HydrophobicContact CE1-CG 4.36Å; Y127-L131 HydrophobicContact CE2-CD1 4.12Å; Y127-L131 HydrophobicContact CE2-CD2 4.05Å; Y127-L131 HydrophobicContact CE2-CG 3.85Å; Y127-L131 PolarHBondContact O-N 3.44Å; S128-L131 PolarHBondContact O-N 2.98Å; G129-L131 VanDerWaalsContact C-N 3.34Å; G129-L131 PolarHBondContact O-N 3.25Å; L131-W134 HydrophobicContact CD2-CE3 4.1Å; L131-W134 HydrophobicContact CD2-CZ3 4.35Å; L131-W134 PolarHBondContact O-N 2.97Å; L131-F135 WeakPolarHBondContact O-CB 3.27Å; L131-F135 PolarHBondContact O-N 3.07Å
132S98.7Very high97.8Very high0 Ų022.5 Ų22.50%013%0.128CC..Hα-helixtrans-61.2-48175.3-173.10000111.7S122 F123 S128 G129 S130 F135 R136 A146 V147S122-S132 WeakPolarHBondContact CB-OG 3.29Å; S122-S132 PolarHBondContact O-OG 3.03Å; S122-S132 PolarHBondContact OG-OG 3.29Å; F123-S132 PolarHBondContact N-OG 3.11Å; S128-S132 PolarHBondContact O-N 3.23Å; G129-S132 WeakPolarHBondContact O-CB 3.23Å; G129-S132 PolarHBondContact O-N 2.81Å; S130-S132 VanDerWaalsContact C-N 3.35Å; S130-S132 PolarHBondContact O-N 3.1Å; S132-F135 PolarHBondContact O-N 2.92Å; S132-R136 PolarHBondContact O-N 3.47Å; S132-R136 VanDerWaalsContact O-N 3.14Å; S132-A146 VanDerWaalsContact O-CB 3.31Å; S132-A146 WeakPolarHBondContact O-CB 3.46Å; S132-A146 WeakPolarHBondContact OG-CB 3.32Å; S132-V147 PolarHBondContact OG-O 3.38Å
133A97.8Very high97.8Very high0 Ų022.6 Ų22.60%013%0.129CC..Hα-helixtrans-60.4-48175.300000111.9G129 S130 R136 G137 A148 V153 V377 Y379G129-A133 PolarHBondContact O-N 2.75Å; S130-A133 PolarHBondContact O-N 3.02Å; A133-R136 PolarHBondContact O-N 2.77Å; A133-G137 PolarHBondContact O-N 2.85Å; A133-A148 HydrophobicContact CB-CB 3.89Å; A133-V153 HydrophobicContact CB-CG1 4.22Å; A133-V377 HydrophobicContact CB-CG1 3.75Å; A133-Y379 HydrophobicContact CB-CE1 3.72Å
134W98.3Very high97.7Very high8 Ų823.7 Ų23.73%0.0313%0.133CC..Hα-helixtrans-69.5-33.4-178.8-58.8-25000112.8L98 Y127 S130 L131 G137 K138 F319 Y367L98-W134 HydrophobicContact CD1-CB 3.72Å; L98-W134 HydrophobicContact CD2-CB 4.16Å; Y127-W134 HydrophobicContact CD2-CZ3 4.49Å; Y127-W134 HydrophobicContact CE2-CZ3 4.05Å; S130-W134 WeakPolarHBondContact O-CB 3.5Å; S130-W134 PolarHBondContact O-N 3.01Å; L131-W134 HydrophobicContact CD2-CE3 4.1Å; L131-W134 HydrophobicContact CD2-CZ3 4.35Å; L131-W134 PolarHBondContact O-N 2.97Å; W134-G137 PolarHBondContact O-N 2.91Å; W134-K138 VanDerWaalsContact O-CB 3.32Å; W134-K138 WeakPolarHBondContact O-CB 3.27Å; W134-K138 WeakPolarHBondContact O-CG 3.41Å; W134-K138 PolarHBondContact O-N 3.36Å; W134-F319 AromaticContact CH2-CE1 3.73Å; W134-F319 HydrophobicContact CH2-CE1 3.73Å; W134-F319 HydrophobicContact CH2-CZ 4.29Å; W134-F319 HydrophobicContact CZ3-CE1 4.16Å; W134-F319 HydrophobicContact CZ3-CZ 4.35Å; W134-Y367 HydrophobicContact CB-CD1 3.82Å; W134-Y367 HydrophobicContact CB-CE1 3.83Å; W134-Y367 AromaticContact CD1-CD1 3.62Å; W134-Y367 AromaticContact CD1-CG 3.8Å; W134-Y367 AromaticContact CD2-CD1 3.66Å; W134-Y367 HydrophobicContact CD2-CD1 3.66Å; W134-Y367 HydrophobicContact CD2-CD2 4Å; W134-Y367 AromaticContact CD2-CE1 3.8Å; W134-Y367 HydrophobicContact CD2-CE1 3.8Å; W134-Y367 HydrophobicContact CD2-CE2 4.13Å; W134-Y367 AromaticContact CD2-CG 3.78Å; W134-Y367 HydrophobicContact CD2-CG 3.78Å; W134-Y367 AromaticContact CE2-CD2 3.79Å; W134-Y367 AromaticContact CE2-CG 3.63Å; W134-Y367 HydrophobicContact CE3-CD1 4.31Å; W134-Y367 HydrophobicContact CE3-CD2 4.29Å; W134-Y367 HydrophobicContact CE3-CE1 4Å; W134-Y367 AromaticContact CE3-CE2 3.98Å; W134-Y367 HydrophobicContact CE3-CE2 3.98Å; W134-Y367 HydrophobicContact CE3-CG 4.45Å; W134-Y367 AromaticContact CE3-CZ 3.83Å; W134-Y367 AromaticContact CG-CD1 3.4Å; W134-Y367 HydrophobicContact CG-CD1 3.4Å; W134-Y367 VanDerWaalsContact CG-CD1 3.4Å; W134-Y367 AromaticContact CG-CE1 3.74Å; W134-Y367 HydrophobicContact CG-CE1 3.74Å; W134-Y367 AromaticContact CG-CG 3.88Å; W134-Y367 HydrophobicContact CG-CG 3.88Å; W134-Y367 HydrophobicContact CH2-CD2 4.21Å; W134-Y367 HydrophobicContact CH2-CE2 4.23Å; W134-Y367 AromaticContact CZ2-CD2 3.89Å; W134-Y367 HydrophobicContact CZ2-CD2 3.89Å; W134-Y367 HydrophobicContact CZ2-CE2 4.35Å; W134-Y367 HydrophobicContact CZ2-CG 4.19Å; W134-Y367 HydrophobicContact CZ3-CD2 4.4Å; W134-Y367 HydrophobicContact CZ3-CE2 4.04Å; W134-Y367 AromaticContact NE1-CD1 3.96Å; W134-Y367 AromaticContact NE1-CG 3.65Å
135F98.6Very high97.7Very high0 Ų023.7 Ų23.70%013%0.133CC..Hα-helixtrans-63-45.9174.3-174.6-130.7000110.4L38 I40 L98 L101 L131 S132 G137 K138 F139 L142 V143L38-F135 HydrophobicContact CD2-CE1 4.27Å; I40-F135 HydrophobicContact CD1-CB 4.4Å; I40-F135 HydrophobicContact CD1-CD1 4.38Å; L98-F135 HydrophobicContact CD2-CB 3.82Å; L101-F135 HydrophobicContact CB-CD1 4.48Å; L101-F135 HydrophobicContact CB-CD2 3.76Å; L101-F135 HydrophobicContact CB-CE1 4.28Å; L101-F135 HydrophobicContact CB-CE2 3.54Å; L101-F135 HydrophobicContact CB-CG 4.26Å; L101-F135 HydrophobicContact CB-CZ 3.83Å; L101-F135 HydrophobicContact CD1-CB 3.89Å; L101-F135 HydrophobicContact CD1-CD1 4.13Å; L101-F135 HydrophobicContact CD1-CD2 3.88Å; L101-F135 HydrophobicContact CD1-CE2 4.48Å; L101-F135 HydrophobicContact CD1-CG 3.71Å; L101-F135 HydrophobicContact CG-CD2 4.5Å; L131-F135 WeakPolarHBondContact O-CB 3.27Å; L131-F135 PolarHBondContact O-N 3.07Å; S132-F135 PolarHBondContact O-N 2.92Å; F135-G137 PolarHBondContact O-N 2.8Å; F135-K138 PolarHBondContact O-N 3.2Å; F135-F139 HydrophobicContact CD2-CB 4.01Å; F135-F139 AromaticContact CD2-CD2 3.62Å; F135-F139 HydrophobicContact CD2-CD2 3.62Å; F135-F139 HydrophobicContact CD2-CE2 4.46Å; F135-F139 HydrophobicContact CD2-CG 4.09Å; F135-F139 HydrophobicContact CE2-CB 3.78Å; F135-F139 AromaticContact CE2-CD2 3.86Å; F135-F139 HydrophobicContact CE2-CD2 3.86Å; F135-F139 AromaticContact CE2-CG 3.92Å; F135-F139 HydrophobicContact CE2-CG 3.92Å; F135-F139 WeakPolarHBondContact O-CA 3.27Å; F135-F139 WeakPolarHBondContact O-CB 3.38Å; F135-F139 PolarHBondContact O-N 3.09Å; F135-L142 HydrophobicContact CE2-CD1 4.41Å; F135-L142 HydrophobicContact CZ-CB 4.15Å; F135-L142 HydrophobicContact CZ-CD1 4.39Å; F135-V143 HydrophobicContact CD1-CB 3.94Å; F135-V143 HydrophobicContact CD1-CG1 3.56Å; F135-V143 HydrophobicContact CD1-CG2 4.47Å; F135-V143 HydrophobicContact CE1-CB 3.74Å; F135-V143 HydrophobicContact CE1-CG1 3.79Å; F135-V143 HydrophobicContact CE1-CG2 4.5Å; F135-V143 HydrophobicContact CG-CG1 4.19Å
136R97.4Very high97.7Very high16 Ų1623.1 Ų23.16%0.0613%0.127CC..Hα-helixtrans-63.2-40.5172.9174.758.5-162157.49.4112.7S132 A133 P140 V143 Y144 A146 Y375 V377S132-R136 PolarHBondContact O-N 3.47Å; S132-R136 VanDerWaalsContact O-N 3.14Å; A133-R136 PolarHBondContact O-N 2.77Å; R136-P140 VanDerWaalsContact NH1-C 3.32Å; R136-P140 VanDerWaalsContact NH1-CB 3.33Å; R136-P140 PolarHBondContact NH1-O 2.82Å; R136-P140 WeakPolarHBondContact O-CA 3.22Å; R136-V143 VanDerWaalsContact CA-CG1 3.48Å; R136-V143 HydrophobicContact CB-CG1 3.89Å; R136-V143 WeakPolarHBondContact CD-O 3.15Å; R136-V143 PolarHBondContact NH1-O 3.46Å; R136-Y144 VanDerWaalsContact CZ-O 3.25Å; R136-Y144 PolarHBondContact NE-O 3.43Å; R136-Y144 PolarHBondContact NH1-O 2.83Å; R136-A146 HydrophobicContact CB-CB 3.64Å; R136-A146 HydrophobicContact CG-CB 4.22Å; R136-Y375 PolarHBondContact NE-O 3Å; R136-V377 HydrophobicContact CB-CG2 3.95Å; R136-V377 HydrophobicContact CG-CG2 3.58Å
137G95.1Very high97.7Very high35 Ų3522.6 Ų22.636%0.36112%0.123SC..Hα-helixtrans-66.5-37.9178.500000114.2A133 W134 F135A133-G137 PolarHBondContact O-N 2.85Å; W134-G137 PolarHBondContact O-N 2.91Å; F135-G137 PolarHBondContact O-N 2.8Å
138K96.6Very high97.6Very high82 Ų8222.5 Ų22.536%0.35712%0.122SC..Hα-helixtrans-95.8-28.3-174.5-65.8-67.7-178.5176.30114L98 W134 F135 P140 Y366L98-K138 HydrophobicContact CD1-CG 4.45Å; W134-K138 VanDerWaalsContact O-CB 3.32Å; W134-K138 WeakPolarHBondContact O-CB 3.27Å; W134-K138 WeakPolarHBondContact O-CG 3.41Å; W134-K138 PolarHBondContact O-N 3.36Å; F135-K138 PolarHBondContact O-N 3.2Å; K138-P140 WeakPolarHBondContact O-CD 3.47Å; K138-Y366 HydrophobicContact CD-CE1 4.37Å; K138-Y366 VanDerWaalsContact CE-O 3.22Å; K138-Y366 WeakPolarHBondContact CE-O 3.44Å; K138-Y366 PolarHBondContact NZ-O 2.8Å
139F97.4Very high97.6Very high55 Ų5522.2 Ų22.224%0.24112%0.121CC..  trans-125.755.1-179.1-58.3-88.2000111.7L98 A102 F135 N141 L142 V143L98-F139 HydrophobicContact CB-CE2 3.98Å; A102-F139 HydrophobicContact CB-CD1 4.12Å; A102-F139 HydrophobicContact CB-CE1 3.98Å; A102-F139 HydrophobicContact CB-CZ 4.43Å; F135-F139 HydrophobicContact CD2-CB 4.01Å; F135-F139 AromaticContact CD2-CD2 3.62Å; F135-F139 HydrophobicContact CD2-CD2 3.62Å; F135-F139 HydrophobicContact CD2-CE2 4.46Å; F135-F139 HydrophobicContact CD2-CG 4.09Å; F135-F139 HydrophobicContact CE2-CB 3.78Å; F135-F139 AromaticContact CE2-CD2 3.86Å; F135-F139 HydrophobicContact CE2-CD2 3.86Å; F135-F139 AromaticContact CE2-CG 3.92Å; F135-F139 HydrophobicContact CE2-CG 3.92Å; F135-F139 WeakPolarHBondContact O-CA 3.27Å; F135-F139 WeakPolarHBondContact O-CB 3.38Å; F135-F139 PolarHBondContact O-N 3.09Å; F139-N141 PolarHBondContact O-N 2.86Å; F139-L142 HydrophobicContact CB-CB 4.23Å; F139-L142 HydrophobicContact CB-CD1 3.98Å; F139-L142 HydrophobicContact CB-CG 4.12Å; F139-L142 HydrophobicContact CD1-CD1 4Å; F139-L142 HydrophobicContact CG-CD1 4.27Å; F139-L142 PolarHBondContact O-N 3.31Å; F139-V143 PolarHBondContact O-N 3.14Å
140P95.6Very high97.6Very high66 Ų6622.2 Ų22.243%0.42912%0.121SC..THydrogen-bonded Turntrans-65.9-11.8-176.329-37000113.8R136 K138R136-P140 VanDerWaalsContact NH1-C 3.32Å; R136-P140 VanDerWaalsContact NH1-CB 3.33Å; R136-P140 PolarHBondContact NH1-O 2.82Å; R136-P140 WeakPolarHBondContact O-CA 3.22Å; K138-P140 WeakPolarHBondContact O-CD 3.47Å
141N95.1Very high97.6Very high131 Ų13122.2 Ų22.270%0.70112%0.12SC*.THydrogen-bonded Turntrans-81.9-14.3172.463.3-60.5000113.4F139F139-N141 PolarHBondContact O-N 2.86Å
142L97.6Very high97.5Very high36 Ų3622.2 Ų22.219%0.18812%0.121CC..THydrogen-bonded Turntrans-104.8-38.6-177.1-57.3-174.6000112.8A102 H105 F135 F139A102-L142 HydrophobicContact CB-CD1 3.62Å; H105-L142 PolarHBondContact CD2-O 3.43Å; H105-L142 PolarHBondContact NE2-O 3.35Å; F135-L142 HydrophobicContact CE2-CD1 4.41Å; F135-L142 HydrophobicContact CZ-CB 4.15Å; F135-L142 HydrophobicContact CZ-CD1 4.39Å; F139-L142 HydrophobicContact CB-CB 4.23Å; F139-L142 HydrophobicContact CB-CD1 3.98Å; F139-L142 HydrophobicContact CB-CG 4.12Å; F139-L142 HydrophobicContact CD1-CD1 4Å; F139-L142 HydrophobicContact CG-CD1 4.27Å; F139-L142 PolarHBondContact O-N 3.31Å
143V97.7Very high97.4Very high1 Ų122.3 Ų22.31%0.00612%0.121CC..  trans-121.6129.6179.264.60000109.6W120 F135 R136 F139 G145W120-V143 HydrophobicContact CB-CG2 4.28Å; F135-V143 HydrophobicContact CD1-CB 3.94Å; F135-V143 HydrophobicContact CD1-CG1 3.56Å; F135-V143 HydrophobicContact CD1-CG2 4.47Å; F135-V143 HydrophobicContact CE1-CB 3.74Å; F135-V143 HydrophobicContact CE1-CG1 3.79Å; F135-V143 HydrophobicContact CE1-CG2 4.5Å; F135-V143 HydrophobicContact CG-CG1 4.19Å; R136-V143 VanDerWaalsContact CA-CG1 3.48Å; R136-V143 HydrophobicContact CB-CG1 3.89Å; R136-V143 WeakPolarHBondContact CD-O 3.15Å; R136-V143 PolarHBondContact NH1-O 3.46Å; F139-V143 PolarHBondContact O-N 3.14Å; V143-G145 WeakPolarHBondContact CG2-O 3.43Å
144Y97.4Very high97.4Very high28 Ų2825.2 Ų25.211%0.1113%0.134CC..SBendtrans-77.9-35.5-172.8-174.7-88.5000113.2T119 W120 I121 R136 R376 W439 T442 A443 E446T119-Y144 HydrophobicContact CG2-CD1 3.98Å; T119-Y144 HydrophobicContact CG2-CD2 4.24Å; T119-Y144 HydrophobicContact CG2-CG 3.65Å; W120-Y144 WeakPolarHBondContact O-CA 3.31Å; W120-Y144 VanDerWaalsContact O-CB 3.29Å; W120-Y144 WeakPolarHBondContact O-CB 3.37Å; W120-Y144 PolarHBondContact O-N 2.96Å; I121-Y144 HydrophobicContact CD1-CD1 4.2Å; R136-Y144 VanDerWaalsContact CZ-O 3.25Å; R136-Y144 PolarHBondContact NE-O 3.43Å; R136-Y144 PolarHBondContact NH1-O 2.83Å; Y144-R376 VanDerWaalsContact CZ-CZ 3.44Å; Y144-R376 WeakPolarHBondContact O-CB 3.43Å; Y144-R376 VanDerWaalsContact O-CD 3.23Å; Y144-R376 WeakPolarHBondContact O-CD 3.21Å; Y144-R376 PolarHBondContact OH-NH1 3.16Å; Y144-R376 VanDerWaalsContact OH-NH1 3.15Å; Y144-R376 PolarHBondContact OH-NH2 3.29Å; Y144-W439 HydrophobicContact CD1-CB 4.07Å; Y144-W439 HydrophobicContact CE1-CB 3.78Å; Y144-W439 HydrophobicContact CE1-CG 4.3Å; Y144-W439 WeakPolarHBondContact CE1-O 3.43Å; Y144-T442 WeakPolarHBondContact OH-CB 3.47Å; Y144-T442 VanDerWaalsContact OH-CG2 3.27Å; Y144-T442 WeakPolarHBondContact OH-CG2 3.47Å; Y144-A443 HydrophobicContact CD1-CB 4.2Å; Y144-A443 HydrophobicContact CD2-CB 3.81Å; Y144-A443 HydrophobicContact CE1-CB 3.88Å; Y144-A443 HydrophobicContact CE2-CB 3.42Å; Y144-A443 VanDerWaalsContact CE2-CB 3.42Å; Y144-A443 HydrophobicContact CG-CB 4.17Å; Y144-A443 VanDerWaalsContact CZ-CB 3.47Å; Y144-A443 PolarHBondContact OH-N 3.17Å; Y144-A443 VanDerWaalsContact OH-N 3.14Å; Y144-E446 WeakPolarHBondContact CE2-OE2 3.29Å; Y144-E446 PolarHBondContact OH-OE2 3.21Å
145G97.6Very high97.4Very high0 Ų025 Ų250%013%0.134CC..EExtended strand (participates in β ladder)trans-155.8163.4177.100000112.1I121 S122 V143 R376I121-G145 VanDerWaalsContact CA-O 3.31Å; I121-G145 WeakPolarHBondContact CA-O 3.46Å; S122-G145 PolarHBondContact N-O 2.99Å; V143-G145 WeakPolarHBondContact CG2-O 3.43Å; G145-R376 CarbonylContact C-O 3.59Å; G145-R376 WeakPolarHBondContact CA-O 3.37Å
146A98.3Very high97.4Very high0 Ų027.7 Ų27.70%015%0.146CC..EExtended strand (participates in β ladder)trans-134133.2-178.500000111.3S122 S132 R136 R376 V377 L378 W439S122-A146 CarbonylContact O-C 3.39Å; S122-A146 WeakPolarHBondContact O-CA 3.32Å; S122-A146 WeakPolarHBondContact OG-CB 3.42Å; S132-A146 VanDerWaalsContact O-CB 3.31Å; S132-A146 WeakPolarHBondContact O-CB 3.46Å; S132-A146 WeakPolarHBondContact OG-CB 3.32Å; R136-A146 HydrophobicContact CB-CB 3.64Å; R136-A146 HydrophobicContact CG-CB 4.22Å; A146-R376 PolarHBondContact N-O 3.1Å; A146-V377 HydrophobicContact CB-CG1 4.34Å; A146-V377 HydrophobicContact CB-CG2 4.33Å; A146-V377 WeakPolarHBondContact O-CA 3.45Å; A146-L378 PolarHBondContact O-N 3.15Å; A146-W439 WeakPolarHBondContact O-CH2 3.37Å
147V98.6Very high97.4Very high6 Ų628.8 Ų28.84%0.03615%0.152CC..EExtended strand (participates in β ladder)trans-97.4117.3162.6-176.60000107.3S122 F123 G124 S132 L378 V380 I432 V436 W439S122-V147 PolarHBondContact O-N 2.83Å; F123-V147 WeakPolarHBondContact CA-O 3.23Å; F123-V147 HydrophobicContact CD1-CB 3.7Å; F123-V147 HydrophobicContact CD1-CG1 4.39Å; F123-V147 HydrophobicContact CD1-CG2 3.88Å; F123-V147 HydrophobicContact CE1-CB 3.99Å; F123-V147 HydrophobicContact CE1-CG2 3.61Å; F123-V147 HydrophobicContact CZ-CG2 4.48Å; G124-V147 PolarHBondContact N-O 2.78Å; S132-V147 PolarHBondContact OG-O 3.38Å; V147-L378 HydrophobicContact CG2-CD2 4.43Å; V147-V380 HydrophobicContact CG1-CG2 4.13Å; V147-I432 HydrophobicContact CG1-CG2 4.11Å; V147-I432 HydrophobicContact CG2-CG2 4.31Å; V147-V436 HydrophobicContact CG2-CG2 3.77Å; V147-W439 HydrophobicContact CG2-CZ3 4.3Å
148A98.1Very high97.5Very high0 Ų029.6 Ų29.60%015%0.149CC..EExtended strand (participates in β ladder)trans-116.690.8-176.800000108.3G129 A133 A151 V377 L378 Y379 V380G129-A148 WeakPolarHBondContact O-CB 3.18Å; A133-A148 HydrophobicContact CB-CB 3.89Å; A148-A151 HydrophobicContact CB-CB 3.91Å; A148-V377 HydrophobicContact CB-CG1 4.23Å; A148-L378 PolarHBondContact N-O 3.06Å; A148-Y379 HydrophobicContact CB-CD1 4.12Å; A148-Y379 HydrophobicContact CB-CE1 4.39Å; A148-V380 PolarHBondContact O-N 3.43Å
149S98.4Very high97.5Very high0 Ų025.7 Ų25.70%013%0.132CC..EExtended strand (participates in β ladder)trans-82.3129.6-179.21780000111.3G124 G125 S126 A151 C411 D413G124-S149 PolarHBondContact O-N 2.75Å; G125-S149 CarbonylContact C-O 3.58Å; G125-S149 VanDerWaalsContact CA-O 3.29Å; G125-S149 WeakPolarHBondContact CA-O 3.44Å; S126-S149 PolarHBondContact N-O 2.99Å; S149-A151 PolarHBondContact O-N 3.46Å; S149-A151 VanDerWaalsContact O-N 3.08Å; S149-C411 WeakPolarHBondContact OG-CA 3.29Å; S149-D413 WeakPolarHBondContact CB-OD2 3.49Å; S149-D413 VanDerWaalsContact OG-CG 3.28Å; S149-D413 PolarHBondContact OG-OD1 2.93Å; S149-D413 PolarHBondContact OG-OD2 3.07Å
150S98.1Very high97.5Very high0 Ų023.9 Ų23.90%013%0.126CC..THydrogen-bonded Turntrans47.541.6175.8-48.30000112.4S126 P152 V380 D385 H410 C411S126-S150 WeakPolarHBondContact CA-O 3.22Å; S150-P152 WeakPolarHBondContact O-CD 3.4Å; S150-V380 WeakPolarHBondContact CA-O 3.44Å; S150-V380 PolarHBondContact N-O 2.71Å; S150-D385 VanDerWaalsContact CB-OD2 3.25Å; S150-D385 WeakPolarHBondContact CB-OD2 3.42Å; S150-D385 PolarHBondContact OG-OD2 3.33Å; S150-H410 VanDerWaalsContact CB-CE1 3.48Å; S150-H410 WeakPolarHBondContact CB-CE1 3.28Å; S150-H410 VanDerWaalsContact CB-ND1 3.33Å; S150-H410 WeakPolarHBondContact CB-ND1 3.42Å; S150-H410 PolarHBondContact O-CE1 3.26Å; S150-C411 PolarHBondContact OG-N 3.15Å
151A97.8Very high97.5Very high0 Ų023.6 Ų23.60%012%0.119CC..  trans-85.7109.6-166.800000111.7G129 A148 S149 V153 S391G129-A151 VanDerWaalsContact C-CB 3.47Å; A148-A151 HydrophobicContact CB-CB 3.91Å; S149-A151 PolarHBondContact O-N 3.46Å; S149-A151 VanDerWaalsContact O-N 3.08Å; A151-V153 VanDerWaalsContact C-N 3.3Å; A151-V153 HydrophobicContact CB-CG1 4.23Å; A151-V153 PolarHBondContact O-N 3.33Å; A151-S391 WeakPolarHBondContact O-CA 3.29Å; A151-S391 VanDerWaalsContact O-CB 3.23Å; A151-S391 WeakPolarHBondContact O-CB 3.1Å; A151-S391 PolarHBondContact O-OG 3.44Å
152P97.8Very high97.6Very high3 Ų317.5 Ų17.52%0.0199%0.086CC..  trans-75.983.9173.933.1-33.8000109.7S126 S130 S150 F321 W387 L390S126-P152 WeakPolarHBondContact O-CD 3.29Å; S130-P152 WeakPolarHBondContact OG-CD 3.34Å; S130-P152 PolarHBondContact OG-O 2.85Å; S150-P152 WeakPolarHBondContact O-CD 3.4Å; P152-F321 HydrophobicContact CB-CE2 4.44Å; P152-F321 HydrophobicContact CB-CZ 4.04Å; P152-F321 HydrophobicContact CG-CE2 4.32Å; P152-F321 HydrophobicContact CG-CZ 4.35Å; P152-W387 HydrophobicContact CB-CE3 3.7Å; P152-W387 HydrophobicContact CB-CZ3 4.18Å; P152-W387 HydrophobicContact CG-CE3 3.98Å; P152-W387 HydrophobicContact CG-CZ3 4.33Å; P152-L390 CarbonylContact C-O 3.5Å; P152-L390 WeakPolarHBondContact CA-O 3.37Å; P152-L390 HydrophobicContact CB-CB 3.83Å; P152-L390 HydrophobicContact CB-CD1 4.48Å
153V96.9Very high97.6Very high1 Ų115.9 Ų15.91%0.0068%0.078CC..  trans-80.9-16.7-179.6-69.40000113.5A133 A151 G369 Y379 L390 V392A133-V153 HydrophobicContact CB-CG1 4.22Å; A151-V153 VanDerWaalsContact C-N 3.3Å; A151-V153 HydrophobicContact CB-CG1 4.23Å; A151-V153 PolarHBondContact O-N 3.33Å; V153-G369 VanDerWaalsContact CG2-O 3.32Å; V153-G369 WeakPolarHBondContact CG2-O 3.2Å; V153-Y379 HydrophobicContact CG1-CE1 3.95Å; V153-Y379 HydrophobicContact CG2-CE1 4.41Å; V153-L390 PolarHBondContact N-O 3.29Å; V153-V392 HydrophobicContact CG2-CG2 3.9Å
154K97.7Very high97.4Very high61 Ų6117.7 Ų17.727%0.2659%0.087SC..SBendtrans-94.9108.5173.9-172.9-171.4-163.5161.50110.3F321 D370 L390K154-F321 WeakPolarHBondContact O-CE1 3.21Å; K154-D370 HydrophobicContact CB-CB 4.13Å; K154-D370 HydrophobicContact CD-CB 4.04Å; K154-D370 WeakPolarHBondContact CE-OD2 3.44Å; K154-D370 HydrophobicContact CG-CB 4.47Å; K154-D370 IonicContact NZ-OD1 3.51Å; K154-D370 IonicContact NZ-OD2 2.69Å; K154-D370 PolarHBondContact NZ-OD2 2.76Å; K154-L390 HydrophobicContact CB-CB 4.37Å; K154-L390 HydrophobicContact CB-CD2 4.45Å; K154-L390 WeakPolarHBondContact CB-O 3.4Å; K154-L390 HydrophobicContact CD-CD2 4.26Å; K154-L390 PolarHBondContact N-O 3.44Å
155A98.3Very high97.4Very high4 Ų416.6 Ų16.63%0.0338%0.083CC..  trans-64.5139.1169.200000110.2I360 T363 N364A155-I360 HydrophobicContact CB-CG2 3.86Å; A155-T363 HydrophobicContact CB-CG2 3.73Å; A155-N364 PolarHBondContact N-OD1 3.14Å; A155-N364 PolarHBondContact O-ND2 3.49Å; A155-N364 PolarHBondContact O-OD1 3.07Å
156K98.1Very high97.4Very high57 Ų5716.6 Ų16.625%0.2488%0.083CC..EExtended strand (participates in β ladder)trans-150.6129.3-178.9-167.3178.5-173.4-179.10110.6D158 F159 E161 F319 G320 F321 L390K156-D158 VanDerWaalsContact CD-O 3.25Å; K156-D158 WeakPolarHBondContact CD-O 3.23Å; K156-D158 WeakPolarHBondContact CE-O 3.41Å; K156-D158 WeakPolarHBondContact CG-O 3.32Å; K156-F159 HydrophobicContact CD-CD2 4.48Å; K156-E161 IonicContact NZ-OE1 4Å; K156-E161 PolarHBondContact NZ-OE1 2.86Å; K156-E161 IonicContact NZ-OE2 2.74Å; K156-E161 PolarHBondContact NZ-OE2 2.99Å; K156-F319 CarbonylContact C-O 3.51Å; K156-F319 PolarHBondContact N-O 2.81Å; K156-G320 CarbonylContact O-C 3.57Å; K156-F321 PolarHBondContact O-N 3.48Å; K156-L390 HydrophobicContact CB-CD1 4.45Å; K156-L390 HydrophobicContact CB-CD2 3.79Å; K156-L390 HydrophobicContact CD-CD2 3.86Å; K156-L390 HydrophobicContact CG-CD2 4.47Å
157L97.7Very high97.3Very high38 Ų3816.8 Ų16.820%0.1999%0.085CC..EExtended strand (participates in β ladder)trans-63.5-66.4-178.5-17961.2000111.1Y322 L338 T342 L356 P357 I360L157-Y322 HydrophobicContact CD1-CD2 3.73Å; L157-Y322 HydrophobicContact CD1-CE2 3.67Å; L157-Y322 WeakPolarHBondContact O-CB 3.43Å; L157-Y322 WeakPolarHBondContact O-CD2 3.43Å; L157-Y322 PolarHBondContact O-N 3.47Å; L157-L338 HydrophobicContact CD1-CD1 4.4Å; L157-L338 HydrophobicContact CD2-CD2 4.23Å; L157-L338 HydrophobicContact CG-CD1 4.13Å; L157-L338 HydrophobicContact CG-CD2 4.24Å; L157-T342 HydrophobicContact CD1-CG2 4.33Å; L157-L356 HydrophobicContact CD1-CB 3.85Å; L157-L356 HydrophobicContact CD1-CD1 4.03Å; L157-P357 HydrophobicContact CD2-CG 4.05Å; L157-I360 HydrophobicContact CB-CD1 3.55Å; L157-I360 HydrophobicContact CD1-CD1 3.56Å; L157-I360 HydrophobicContact CG-CD1 4.12Å
158D97.2Very high97.2Very high53 Ų5321.6 Ų21.628%0.28311%0.11SC..EExtended strand (participates in β ladder)trans-97.2116.8178.7-172.54.8000109.6K156 T324 L338K156-D158 VanDerWaalsContact CD-O 3.25Å; K156-D158 WeakPolarHBondContact CD-O 3.23Å; K156-D158 WeakPolarHBondContact CE-O 3.41Å; K156-D158 WeakPolarHBondContact CG-O 3.32Å; D158-T324 WeakPolarHBondContact OD1-CB 2.96Å; D158-T324 WeakPolarHBondContact OD1-CG2 3.38Å; D158-T324 PolarHBondContact OD1-OG1 3.08Å; D158-L338 HydrophobicContact CB-CD1 4.12Å; D158-L338 HydrophobicContact CB-CD2 3.96Å
159F97.1Very high97.2Very high0 Ų021.7 Ų21.70%011%0.111CC..  trans-116.955.7-175.4-172.7-154.7000111.8K156 E161 Y162 Y322 P386 W387 E389 L390K156-F159 HydrophobicContact CD-CD2 4.48Å; F159-E161 HydrophobicContact CD2-CB 4.29Å; F159-E161 HydrophobicContact CE2-CB 4.04Å; F159-E161 PolarHBondContact O-N 3.26Å; F159-Y162 HydrophobicContact CD1-CD2 4.16Å; F159-Y162 HydrophobicContact CD1-CG 4.47Å; F159-Y162 AromaticContact CE1-CD2 3.62Å; F159-Y162 HydrophobicContact CE1-CD2 3.62Å; F159-Y162 HydrophobicContact CE1-CG 4.17Å; F159-Y162 HydrophobicContact CZ-CD2 4.2Å; F159-Y162 VanDerWaalsContact O-CB 3.31Å; F159-Y162 WeakPolarHBondContact O-CB 3.47Å; F159-Y162 PolarHBondContact O-N 3.2Å; F159-Y322 WeakPolarHBondContact CA-O 3.48Å; F159-Y322 PolarHBondContact N-O 3.41Å; F159-P386 WeakPolarHBondContact CZ-O 3.45Å; F159-W387 HydrophobicContact CD1-CE3 4.38Å; F159-W387 HydrophobicContact CD1-CZ3 4.07Å; F159-W387 HydrophobicContact CE1-CD2 4.25Å; F159-W387 AromaticContact CE1-CE3 3.63Å; F159-W387 HydrophobicContact CE1-CE3 3.63Å; F159-W387 AromaticContact CE1-CZ3 3.79Å; F159-W387 HydrophobicContact CE1-CZ3 3.79Å; F159-E389 HydrophobicContact CE2-CB 3.79Å; F159-E389 HydrophobicContact CZ-CB 4.12Å; F159-L390 HydrophobicContact CD1-CD1 3.5Å; F159-L390 HydrophobicContact CD1-CG 4.3Å; F159-L390 HydrophobicContact CD2-CD1 4.04Å; F159-L390 HydrophobicContact CD2-CD2 4.16Å; F159-L390 HydrophobicContact CD2-CG 4.11Å; F159-L390 HydrophobicContact CE1-CD1 3.39Å; F159-L390 HydrophobicContact CE1-CG 3.87Å; F159-L390 HydrophobicContact CE2-CD1 3.98Å; F159-L390 HydrophobicContact CE2-CD2 4.06Å; F159-L390 HydrophobicContact CE2-CG 3.7Å; F159-L390 HydrophobicContact CG-CD1 3.83Å; F159-L390 HydrophobicContact CG-CG 4.41Å; F159-L390 HydrophobicContact CZ-CD1 3.67Å; F159-L390 HydrophobicContact CZ-CD2 4.43Å; F159-L390 HydrophobicContact CZ-CG 3.58Å
160S95.9Very high97.2Very high17 Ų1721.7 Ų21.712%0.11911%0.111CC..THydrogen-bonded Turntrans-62.9-25.9176610000113.7Y162 S163 N164 T324S160-Y162 PolarHBondContact O-N 2.81Å; S160-S163 PolarHBondContact O-N 3.35Å; S160-S163 VanDerWaalsContact O-N 3.11Å; S160-N164 PolarHBondContact O-N 3.02Å; S160-T324 WeakPolarHBondContact CB-OG1 3.32Å
161E96.1Very high97.2Very high59 Ų5924.8 Ų24.828%0.27613%0.127SC..Hα-helixtrans-63.4-23.1178.3-61.986.2165.600113K156 F159 S163 N164 V165 E389K156-E161 IonicContact NZ-OE1 4Å; K156-E161 PolarHBondContact NZ-OE1 2.86Å; K156-E161 IonicContact NZ-OE2 2.74Å; K156-E161 PolarHBondContact NZ-OE2 2.99Å; F159-E161 HydrophobicContact CD2-CB 4.29Å; F159-E161 HydrophobicContact CE2-CB 4.04Å; F159-E161 PolarHBondContact O-N 3.26Å; E161-S163 VanDerWaalsContact C-N 3.31Å; E161-S163 PolarHBondContact O-N 3.27Å; E161-N164 WeakPolarHBondContact O-CB 3.13Å; E161-N164 PolarHBondContact O-N 2.85Å; E161-N164 VanDerWaalsContact O-N 3.14Å; E161-V165 PolarHBondContact O-N 2.69Å; E161-E389 HydrophobicContact CB-CB 4.37Å; E161-E389 HydrophobicContact CB-CG 4.14Å
162Y97.5Very high97.1Very high4 Ų426.9 Ų26.92%0.01614%0.138CC..Hα-helixtrans-51.9-53.7171.3-174.7-73.7000110.3F159 S160 N164 V165 V166 M232 Q236 Q323 P386 W387F159-Y162 HydrophobicContact CD1-CD2 4.16Å; F159-Y162 HydrophobicContact CD1-CG 4.47Å; F159-Y162 AromaticContact CE1-CD2 3.62Å; F159-Y162 HydrophobicContact CE1-CD2 3.62Å; F159-Y162 HydrophobicContact CE1-CG 4.17Å; F159-Y162 HydrophobicContact CZ-CD2 4.2Å; F159-Y162 VanDerWaalsContact O-CB 3.31Å; F159-Y162 WeakPolarHBondContact O-CB 3.47Å; F159-Y162 PolarHBondContact O-N 3.2Å; S160-Y162 PolarHBondContact O-N 2.81Å; Y162-N164 VanDerWaalsContact C-N 3.25Å; Y162-N164 PolarHBondContact O-N 3.46Å; Y162-V165 PolarHBondContact O-N 2.61Å; Y162-V166 HydrophobicContact CD1-CG2 3.96Å; Y162-V166 HydrophobicContact CE1-CG2 3.64Å; Y162-V166 WeakPolarHBondContact O-CG2 3.28Å; Y162-V166 PolarHBondContact O-N 3.11Å; Y162-M232 HydrophobicContact CD1-CE 3.57Å; Y162-M232 HydrophobicContact CD1-CG 4.42Å; Y162-M232 HydrophobicContact CE1-CB 3.81Å; Y162-M232 HydrophobicContact CE1-CE 3.23Å; Y162-M232 HydrophobicContact CE1-CG 3.76Å; Y162-M232 HydrophobicContact CE1-SD 4.21Å; Y162-Q236 PolarHBondContact OH-OE1 2.98Å; Y162-Q323 HydrophobicContact CD1-CG 4.16Å; Y162-Q323 HydrophobicContact CD2-CG 3.96Å; Y162-Q323 HydrophobicContact CE2-CG 4.49Å; Y162-Q323 HydrophobicContact CG-CB 4.5Å; Y162-Q323 HydrophobicContact CG-CG 3.79Å; Y162-P386 HydrophobicContact CD1-CB 3.9Å; Y162-P386 HydrophobicContact CD1-CG 4.37Å; Y162-P386 HydrophobicContact CD2-CB 3.42Å; Y162-P386 VanDerWaalsContact CD2-CB 3.42Å; Y162-P386 HydrophobicContact CD2-CG 4.4Å; Y162-P386 HydrophobicContact CE1-CB 3.88Å; Y162-P386 HydrophobicContact CE1-CG 3.93Å; Y162-P386 HydrophobicContact CE2-CB 3.47Å; Y162-P386 VanDerWaalsContact CE2-CB 3.47Å; Y162-P386 HydrophobicContact CE2-CG 4.03Å; Y162-P386 HydrophobicContact CG-CB 3.64Å; Y162-W387 HydrophobicContact CE2-CD2 4.36Å; Y162-W387 AromaticContact CE2-CE2 3.84Å; Y162-W387 HydrophobicContact CE2-CG 4.48Å; Y162-W387 HydrophobicContact CE2-CZ2 4.27Å; Y162-W387 AromaticContact CE2-NE1 3.6Å
163S96.7Very high97.1Very high2 Ų234.4 Ų34.41%0.01417%0.172CC..Hα-helixtrans-63.1-32.7-179.5-59.80000112.3S160 E161 V166 G167 T324 C330 P331S160-S163 PolarHBondContact O-N 3.35Å; S160-S163 VanDerWaalsContact O-N 3.11Å; E161-S163 VanDerWaalsContact C-N 3.31Å; E161-S163 PolarHBondContact O-N 3.27Å; S163-V166 WeakPolarHBondContact O-CB 3.28Å; S163-V166 PolarHBondContact O-N 3.01Å; S163-G167 PolarHBondContact O-N 2.74Å; S163-T324 PolarHBondContact OG-O 3.21Å; S163-T324 VanDerWaalsContact OG-O 3.14Å; S163-C330 WeakPolarHBondContact CB-SG 3.35Å; S163-P331 WeakPolarHBondContact O-CD 3.48Å
164N94.7Very high97Very high38 Ų3837 Ų3720%0.20319%0.194CC..Hα-helixtrans-67.2-45.7177-67.7-13.7000111.8S160 E161 Y162 V166 G167 L168 T329 C330S160-N164 PolarHBondContact O-N 3.02Å; E161-N164 WeakPolarHBondContact O-CB 3.13Å; E161-N164 PolarHBondContact O-N 2.85Å; E161-N164 VanDerWaalsContact O-N 3.14Å; Y162-N164 VanDerWaalsContact C-N 3.25Å; Y162-N164 PolarHBondContact O-N 3.46Å; N164-V166 VanDerWaalsContact C-N 3.28Å; N164-V166 PolarHBondContact O-N 3.04Å; N164-G167 PolarHBondContact O-N 2.9Å; N164-G167 VanDerWaalsContact O-N 3.16Å; N164-L168 WeakPolarHBondContact O-CG 3.22Å; N164-L168 PolarHBondContact O-N 2.67Å; N164-T329 VanDerWaalsContact CG-OG1 3.23Å; N164-T329 PolarHBondContact ND2-OG1 2.77Å; N164-T329 WeakPolarHBondContact OD1-CB 3.41Å; N164-T329 PolarHBondContact OD1-OG1 3.14Å; N164-C330 PolarHBondContact OD1-N 2.78Å
165V96.4Very high96.9Very high5 Ų534.1 Ų34.13%0.0318%0.182CC..Hα-helixtrans-64.1-37.4175.7177.90000111E161 Y162 G167 L168 G169 P386 E389E161-V165 PolarHBondContact O-N 2.69Å; Y162-V165 PolarHBondContact O-N 2.61Å; V165-G167 VanDerWaalsContact C-N 3.32Å; V165-G167 PolarHBondContact O-N 3.1Å; V165-L168 PolarHBondContact O-N 2.84Å; V165-L168 VanDerWaalsContact O-N 3.16Å; V165-G169 PolarHBondContact O-N 3.16Å; V165-P386 HydrophobicContact CB-CB 4.22Å; V165-P386 HydrophobicContact CG1-CB 4.36Å; V165-P386 HydrophobicContact CG1-CG 4.44Å; V165-E389 HydrophobicContact CG2-CG 3.57Å
166V97.8Very high96.8Very high0 Ų035.3 Ų35.30%019%0.194CC..Hα-helixtrans-57.1-47.5172.2172.60000110.8Y162 S163 N164 L168 G169 L170 I231 M232 V235 F332 P386Y162-V166 HydrophobicContact CD1-CG2 3.96Å; Y162-V166 HydrophobicContact CE1-CG2 3.64Å; Y162-V166 WeakPolarHBondContact O-CG2 3.28Å; Y162-V166 PolarHBondContact O-N 3.11Å; S163-V166 WeakPolarHBondContact O-CB 3.28Å; S163-V166 PolarHBondContact O-N 3.01Å; N164-V166 VanDerWaalsContact C-N 3.28Å; N164-V166 PolarHBondContact O-N 3.04Å; V166-L168 VanDerWaalsContact C-N 3.35Å; V166-L168 PolarHBondContact O-N 3.23Å; V166-G169 PolarHBondContact O-N 2.81Å; V166-G169 VanDerWaalsContact O-N 3.16Å; V166-L170 WeakPolarHBondContact O-CG 3.41Å; V166-L170 PolarHBondContact O-N 2.92Å; V166-I231 HydrophobicContact CG1-CG2 4.11Å; V166-M232 HydrophobicContact CG1-CG 4.38Å; V166-M232 HydrophobicContact CG2-CB 4.48Å; V166-M232 HydrophobicContact CG2-CG 4.13Å; V166-V235 HydrophobicContact CG1-CB 4.23Å; V166-V235 HydrophobicContact CG1-CG2 3.89Å; V166-V235 HydrophobicContact CG2-CB 4.35Å; V166-V235 HydrophobicContact CG2-CG1 4.35Å; V166-F332 HydrophobicContact CG1-CE2 4.13Å; V166-F332 HydrophobicContact CG1-CZ 3.63Å; V166-P386 HydrophobicContact CG2-CB 4.23Å; V166-P386 HydrophobicContact CG2-CG 3.48Å; V166-P386 VanDerWaalsContact CG2-CG 3.48Å
167G97.1Very high96.8Very high4 Ų432.9 Ų32.94%0.04119%0.186CC..Hα-helixtrans-57-43.6174.100000113.5S163 N164 V165 L170 M171S163-G167 PolarHBondContact O-N 2.74Å; N164-G167 PolarHBondContact O-N 2.9Å; N164-G167 VanDerWaalsContact O-N 3.16Å; V165-G167 VanDerWaalsContact C-N 3.32Å; V165-G167 PolarHBondContact O-N 3.1Å; G167-L170 PolarHBondContact O-N 3Å; G167-M171 PolarHBondContact O-N 3.18Å
168L96.6Very high96.8Very high107 Ų10732.4 Ų32.456%0.5619%0.186SC*.Hα-helixtrans-65.1-37.8175.8-66.4174.9000112.4N164 V165 V166 L170 M171 N172N164-L168 WeakPolarHBondContact O-CG 3.22Å; N164-L168 PolarHBondContact O-N 2.67Å; V165-L168 PolarHBondContact O-N 2.84Å; V165-L168 VanDerWaalsContact O-N 3.16Å; V166-L168 VanDerWaalsContact C-N 3.35Å; V166-L168 PolarHBondContact O-N 3.23Å; L168-L170 VanDerWaalsContact C-N 3.32Å; L168-L170 PolarHBondContact O-N 3.28Å; L168-M171 PolarHBondContact O-N 3.26Å; L168-M171 VanDerWaalsContact O-N 3.15Å; L168-N172 PolarHBondContact O-N 3.18Å; L168-N172 VanDerWaalsContact O-N 3.16Å
169G97.2Very high96.8Very high2 Ų236.9 Ų36.92%0.02121%0.205CC..Hα-helixtrans-59.3-42.5173.400000112.1V165 V166 M171 N172V165-G169 PolarHBondContact O-N 3.16Å; V166-G169 PolarHBondContact O-N 2.81Å; V166-G169 VanDerWaalsContact O-N 3.16Å; G169-M171 PolarHBondContact O-N 2.84Å; G169-N172 WeakPolarHBondContact O-CB 3.13Å; G169-N172 PolarHBondContact O-N 2.93Å; G169-N172 VanDerWaalsContact O-N 3.1Å
170L98.3Very high96.8Very high0 Ų042 Ų420%023%0.227CC..Hα-helixtrans-66.3-21.9176.3-63.1175.7000113.7V166 G167 L168 G177 S178 L182 V185 I231 V235 L249V166-L170 WeakPolarHBondContact O-CG 3.41Å; V166-L170 PolarHBondContact O-N 2.92Å; G167-L170 PolarHBondContact O-N 3Å; L168-L170 VanDerWaalsContact C-N 3.32Å; L168-L170 PolarHBondContact O-N 3.28Å; L170-G177 CarbonylContact O-C 3.42Å; L170-G177 WeakPolarHBondContact O-CA 3.24Å; L170-S178 PolarHBondContact O-N 3.15Å; L170-S178 VanDerWaalsContact O-O 3.11Å; L170-L182 HydrophobicContact CB-CB 4.29Å; L170-L182 HydrophobicContact CB-CD1 4.46Å; L170-L182 HydrophobicContact CD1-CD1 4.14Å; L170-V185 HydrophobicContact CD1-CB 4.2Å; L170-V185 HydrophobicContact CD1-CG1 4.11Å; L170-V185 HydrophobicContact CD1-CG2 4.03Å; L170-I231 HydrophobicContact CD1-CG2 4.08Å; L170-I231 HydrophobicContact CD2-CG2 4.34Å; L170-V235 HydrophobicContact CD2-CG2 3.97Å; L170-V235 HydrophobicContact CG-CG2 4.29Å; L170-L249 HydrophobicContact CD2-CD2 3.42Å; L170-L249 VanDerWaalsContact CD2-CD2 3.42Å; L170-L249 HydrophobicContact CD2-CG 4.38Å
171M97.6Very high96.9Very high66 Ų6641.1 Ų41.133%0.32522%0.221SC..Hα-helixtrans-86.9-18.7173.9-65.8174.771.200113.1G167 L168 G169 E173 E179 L182G167-M171 PolarHBondContact O-N 3.18Å; L168-M171 PolarHBondContact O-N 3.26Å; L168-M171 VanDerWaalsContact O-N 3.15Å; G169-M171 PolarHBondContact O-N 2.84Å; M171-E173 PolarHBondContact O-N 3.34Å; M171-E173 VanDerWaalsContact O-N 3.12Å; M171-E179 HydrophobicContact CE-CG 3.89Å; M171-L182 HydrophobicContact CG-CB 3.81Å; M171-L182 HydrophobicContact CG-CD2 3.48Å; M171-L182 VanDerWaalsContact CG-CD2 3.48Å; M171-L182 HydrophobicContact CG-CG 4.26Å; M171-L182 HydrophobicContact SD-CD2 3.36Å; M171-L182 WeakPolarHBondContact SD-CD2 3.18Å
172N97.1Very high97Very high44 Ų4438.7 Ų38.724%0.23521%0.21CC..  trans-76.4104-168.8-176.7-4.9000111.8L168 G169 A174 V175 G177L168-N172 PolarHBondContact O-N 3.18Å; L168-N172 VanDerWaalsContact O-N 3.16Å; G169-N172 WeakPolarHBondContact O-CB 3.13Å; G169-N172 PolarHBondContact O-N 2.93Å; G169-N172 VanDerWaalsContact O-N 3.1Å; N172-A174 PolarHBondContact O-N 3.3Å; N172-A174 VanDerWaalsContact O-N 3.16Å; N172-A174 VanDerWaalsContact OD1-CB 3.27Å; N172-A174 WeakPolarHBondContact OD1-CB 3.04Å; N172-A174 PolarHBondContact OD1-N 2.91Å; N172-V175 HydrophobicContact CB-CG2 3.8Å; N172-V175 WeakPolarHBondContact O-CG2 3.21Å; N172-V175 PolarHBondContact O-N 3.5Å; N172-V175 VanDerWaalsContact O-N 3.1Å; N172-G177 WeakPolarHBondContact O-CA 3.44Å; N172-G177 PolarHBondContact O-N 3.48Å
173E96.8Very high97Very high160 Ų16041.1 Ų41.175%0.74823%0.231SC*.G310 helixtrans-59.2-28.2-179.5-61.8-171.1161.800113.4M171 V175 G176 G177M171-E173 PolarHBondContact O-N 3.34Å; M171-E173 VanDerWaalsContact O-N 3.12Å; E173-V175 PolarHBondContact O-N 3.02Å; E173-G176 PolarHBondContact O-N 3.37Å; E173-G176 VanDerWaalsContact O-N 3.1Å; E173-G177 WeakPolarHBondContact CA-O 3.36Å
174A94.9Very high97.1Very high56 Ų5643.1 Ų43.146%0.46324%0.239SC..G310 helixtrans-61.3-31.6178.900000111.8N172 D407 R422N172-A174 PolarHBondContact O-N 3.3Å; N172-A174 VanDerWaalsContact O-N 3.16Å; N172-A174 VanDerWaalsContact OD1-CB 3.27Å; N172-A174 WeakPolarHBondContact OD1-CB 3.04Å; N172-A174 PolarHBondContact OD1-N 2.91Å; A174-D407 HydrophobicContact CB-CB 4.21Å; A174-R422 PolarHBondContact O-NH1 2.98Å; A174-R422 PolarHBondContact O-NH2 3.19Å
175V95.6Very high97.3Very high0 Ų041.3 Ų41.30%023%0.229CC..G310 helixtrans-102.814.4179-62.30000113.1N172 E173 I246 K247 V384 D407N172-V175 HydrophobicContact CB-CG2 3.8Å; N172-V175 WeakPolarHBondContact O-CG2 3.21Å; N172-V175 PolarHBondContact O-N 3.5Å; N172-V175 VanDerWaalsContact O-N 3.1Å; E173-V175 PolarHBondContact O-N 3.02Å; V175-I246 HydrophobicContact CB-CD1 4.22Å; V175-I246 HydrophobicContact CG2-CB 4.41Å; V175-I246 HydrophobicContact CG2-CD1 3.68Å; V175-I246 HydrophobicContact CG2-CG2 4.1Å; V175-K247 PolarHBondContact O-N 2.99Å; V175-V384 HydrophobicContact CG1-CG1 4.1Å; V175-V384 HydrophobicContact CG2-CG1 4.09Å; V175-D407 HydrophobicContact CG1-CB 3.97Å
176G96Very high97.3Very high29 Ų2946 Ų4630%0.29925%0.247SC..THydrogen-bonded Turntrans85.312179.800000114.7E173 C250E173-G176 PolarHBondContact O-N 3.37Å; E173-G176 VanDerWaalsContact O-N 3.1Å; G176-C250 WeakPolarHBondContact O-CB 3.39Å
177G97.6Very high97.3Very high7 Ų749.5 Ų49.57%0.07226%0.263CS..  trans-75.2175.517100000113.7L170 N172 E173L170-G177 CarbonylContact O-C 3.42Å; L170-G177 WeakPolarHBondContact O-CA 3.24Å; N172-G177 WeakPolarHBondContact O-CA 3.44Å; N172-G177 PolarHBondContact O-N 3.48Å; E173-G177 WeakPolarHBondContact CA-O 3.36Å
178S98.1Very high97.3Very high28 Ų2849.3 Ų49.320%0.19626%0.261CS..  trans-166.6158.4168.5570000110.7L170 K180 C181 L182L170-S178 PolarHBondContact O-N 3.15Å; L170-S178 VanDerWaalsContact O-O 3.11Å; S178-K180 PolarHBondContact O-N 2.91Å; S178-C181 WeakPolarHBondContact O-CA 2.98Å; S178-C181 VanDerWaalsContact O-CB 3.29Å; S178-C181 WeakPolarHBondContact O-CB 3.27Å; S178-C181 PolarHBondContact O-N 2.77Å; S178-C181 WeakPolarHBondContact OG-CB 3.43Å; S178-C181 PolarHBondContact OG-N 2.99Å; S178-C181 VanDerWaalsContact OG-N 3.15Å; S178-L182 PolarHBondContact O-N 3.27Å
179E97.8Very high97.4Very high147 Ų14744.3 Ų44.369%0.68724%0.235SC*.Hα-helixtrans-54.9-37.6173.2-57.4-168.8158.400112.2M171 C181 L182 A183M171-E179 HydrophobicContact CE-CG 3.89Å; E179-C181 VanDerWaalsContact C-N 3.31Å; E179-C181 PolarHBondContact O-N 2.59Å; E179-L182 PolarHBondContact O-N 3.27Å; E179-A183 WeakPolarHBondContact O-CB 3.44Å; E179-A183 PolarHBondContact O-N 3.4Å
180K97.5Very high97.4Very high106 Ų10648.9 Ų48.946%0.46126%0.262SS..Hα-helixtrans-63.4-35.8176.1-172-174.8178-167.20112.3S178 K184 T254S178-K180 PolarHBondContact O-N 2.91Å; K180-K184 WeakPolarHBondContact O-CB 3.35Å; K180-K184 VanDerWaalsContact O-CG 3.32Å; K180-K184 WeakPolarHBondContact O-CG 3.39Å; K180-K184 PolarHBondContact O-N 3.36Å; K180-T254 HydrophobicContact CB-CG2 4.31Å; K180-T254 HydrophobicContact CD-CG2 4.21Å; K180-T254 HydrophobicContact CG-CG2 4.1Å; K180-T254 PolarHBondContact NZ-O 3.39Å
181C98.3Very high97.3Very high0 Ų051.5 Ų51.50%028%0.276CS..Hα-helixtrans-64-53176.5179.80000110.6S178 E179 A183 K184 V185 C250 T254S178-C181 WeakPolarHBondContact O-CA 2.98Å; S178-C181 VanDerWaalsContact O-CB 3.29Å; S178-C181 WeakPolarHBondContact O-CB 3.27Å; S178-C181 PolarHBondContact O-N 2.77Å; S178-C181 WeakPolarHBondContact OG-CB 3.43Å; S178-C181 PolarHBondContact OG-N 2.99Å; S178-C181 VanDerWaalsContact OG-N 3.15Å; E179-C181 VanDerWaalsContact C-N 3.31Å; E179-C181 PolarHBondContact O-N 2.59Å; C181-A183 VanDerWaalsContact C-N 3.31Å; C181-A183 PolarHBondContact O-N 3.42Å; C181-K184 PolarHBondContact O-N 3.27Å; C181-K184 VanDerWaalsContact O-N 3.08Å; C181-V185 PolarHBondContact O-N 2.04Å; C181-C250 HydrophobicContact CB-CB 3.64Å; C181-C250 WeakPolarHBondContact CB-SG 3.32Å; C181-C250 WeakPolarHBondContact SG-CA 3.46Å; C181-C250 WeakPolarHBondContact SG-CB 3.47Å; C181-C250 CovalentContact SG-SG 2.04Å; C181-C250 PolarHBondContact SG-SG 3.39Å; C181-T254 HydrophobicContact CB-CG2 3.94Å
182L98.2Very high97.3Very high8 Ų848.4 Ų48.44%0.04226%0.26CS..Hα-helixtrans-56.3-45.8176.6176.461.9000111.7L170 M171 S178 E179 K184 V185 R186 P331L170-L182 HydrophobicContact CB-CB 4.29Å; L170-L182 HydrophobicContact CB-CD1 4.46Å; L170-L182 HydrophobicContact CD1-CD1 4.14Å; M171-L182 HydrophobicContact CG-CB 3.81Å; M171-L182 HydrophobicContact CG-CD2 3.48Å; M171-L182 VanDerWaalsContact CG-CD2 3.48Å; M171-L182 HydrophobicContact CG-CG 4.26Å; M171-L182 HydrophobicContact SD-CD2 3.36Å; M171-L182 WeakPolarHBondContact SD-CD2 3.18Å; S178-L182 PolarHBondContact O-N 3.27Å; E179-L182 PolarHBondContact O-N 3.27Å; L182-K184 VanDerWaalsContact C-N 3.27Å; L182-K184 PolarHBondContact O-N 3.04Å; L182-V185 PolarHBondContact O-N 3.13Å; L182-R186 HydrophobicContact CD1-CG 4.41Å; L182-R186 PolarHBondContact O-N 3.44Å; L182-P331 HydrophobicContact CD1-CB 3.67Å
183A97.6Very high97.2Very high54 Ų5449 Ų4945%0.44626%0.262SS..Hα-helixtrans-58.9-39.6178.200000112.2E179 C181 E187E179-A183 WeakPolarHBondContact O-CB 3.44Å; E179-A183 PolarHBondContact O-N 3.4Å; C181-A183 VanDerWaalsContact C-N 3.31Å; C181-A183 PolarHBondContact O-N 3.42Å; A183-E187 WeakPolarHBondContact O-CB 3.38Å; A183-E187 PolarHBondContact O-N 2.9Å
184K97.7Very high97.1Very high44 Ų4443.2 Ų43.219%0.19124%0.242CC..Hα-helixtrans-73.1-32.7177.5-73.2-70.8168.1-161.70113.2K180 C181 L182 E187 A188 M253 A265K180-K184 WeakPolarHBondContact O-CB 3.35Å; K180-K184 VanDerWaalsContact O-CG 3.32Å; K180-K184 WeakPolarHBondContact O-CG 3.39Å; K180-K184 PolarHBondContact O-N 3.36Å; C181-K184 PolarHBondContact O-N 3.27Å; C181-K184 VanDerWaalsContact O-N 3.08Å; L182-K184 VanDerWaalsContact C-N 3.27Å; L182-K184 PolarHBondContact O-N 3.04Å; K184-E187 WeakPolarHBondContact CD-OE2 3.32Å; K184-E187 WeakPolarHBondContact CE-OE2 3.42Å; K184-E187 IonicContact NZ-OE1 2.77Å; K184-E187 PolarHBondContact NZ-OE1 2.64Å; K184-E187 IonicContact NZ-OE2 3.81Å; K184-E187 PolarHBondContact NZ-OE2 2.79Å; K184-A188 WeakPolarHBondContact O-CB 3.26Å; K184-A188 PolarHBondContact O-N 3.07Å; K184-M253 HydrophobicContact CB-CB 4.28Å; K184-M253 HydrophobicContact CB-CE 4.14Å; K184-M253 VanDerWaalsContact O-CE 3.32Å; K184-M253 WeakPolarHBondContact O-CE 3.21Å; K184-A265 HydrophobicContact CD-CB 4.12Å; K184-A265 WeakPolarHBondContact O-CB 3.36Å
185V98.2Very high97.2Very high0 Ų041.7 Ų41.70%023%0.227CC..Hα-helixtrans-64.3-50.1171.51690000110.3L170 C181 L182 E187 A188 F189 I231 M253 F332L170-V185 HydrophobicContact CD1-CB 4.2Å; L170-V185 HydrophobicContact CD1-CG1 4.11Å; L170-V185 HydrophobicContact CD1-CG2 4.03Å; C181-V185 PolarHBondContact O-N 2.04Å; L182-V185 PolarHBondContact O-N 3.13Å; V185-E187 VanDerWaalsContact C-N 3.34Å; V185-E187 PolarHBondContact O-N 2.85Å; V185-A188 WeakPolarHBondContact O-CB 3.24Å; V185-A188 PolarHBondContact O-N 2.79Å; V185-F189 HydrophobicContact CG1-CD2 4.21Å; V185-F189 HydrophobicContact CG1-CE2 4.26Å; V185-F189 WeakPolarHBondContact O-CD2 3.47Å; V185-F189 PolarHBondContact O-N 3.07Å; V185-F189 VanDerWaalsContact O-N 3.14Å; V185-I231 HydrophobicContact CB-CD1 4.46Å; V185-I231 HydrophobicContact CG1-CD1 3.54Å; V185-I231 HydrophobicContact CG2-CD1 4.08Å; V185-M253 HydrophobicContact CG2-CE 4.19Å; V185-M253 HydrophobicContact CG2-CG 4.15Å; V185-F332 HydrophobicContact CG1-CE1 4.27Å
186R97.8Very high97.2Very high105 Ų10541.8 Ų41.840%0.39623%0.227SC..Hα-helixtrans-55.3-48.2175.5-76.6178.1170.6159.3-0.5112.3L182 A188 F189 V190 T329 P331L182-R186 HydrophobicContact CD1-CG 4.41Å; L182-R186 PolarHBondContact O-N 3.44Å; R186-A188 VanDerWaalsContact C-N 3.27Å; R186-A188 PolarHBondContact O-N 2.93Å; R186-F189 PolarHBondContact O-N 2.99Å; R186-V190 WeakPolarHBondContact O-CG2 3.46Å; R186-V190 PolarHBondContact O-N 2.8Å; R186-V190 VanDerWaalsContact O-N 3.1Å; R186-T329 PolarHBondContact NH2-O 3.19Å; R186-P331 HydrophobicContact CG-CB 4.14Å
187E97.4Very high97.1Very high73 Ų7346.3 Ų46.334%0.34124%0.244SC..Hα-helixtrans-59.1-38.4176.9-173.4-171.615000112A183 K184 V185 L191 A265A183-E187 WeakPolarHBondContact O-CB 3.38Å; A183-E187 PolarHBondContact O-N 2.9Å; K184-E187 WeakPolarHBondContact CD-OE2 3.32Å; K184-E187 WeakPolarHBondContact CE-OE2 3.42Å; K184-E187 IonicContact NZ-OE1 2.77Å; K184-E187 PolarHBondContact NZ-OE1 2.64Å; K184-E187 IonicContact NZ-OE2 3.81Å; K184-E187 PolarHBondContact NZ-OE2 2.79Å; V185-E187 VanDerWaalsContact C-N 3.34Å; V185-E187 PolarHBondContact O-N 2.85Å; E187-L191 HydrophobicContact CG-CD1 4.06Å; E187-L191 WeakPolarHBondContact O-CB 3.37Å; E187-L191 WeakPolarHBondContact O-CG 3.39Å; E187-L191 PolarHBondContact O-N 3.43Å; E187-A265 HydrophobicContact CB-CB 3.76Å; E187-A265 HydrophobicContact CG-CB 3.67Å
188A98.1Very high97Very high0 Ų051.9 Ų51.90%027%0.272CS..Hα-helixtrans-63.6-47.617800000112K184 V185 R186 V190 L191 V192 M253 A265 Y269K184-A188 WeakPolarHBondContact O-CB 3.26Å; K184-A188 PolarHBondContact O-N 3.07Å; V185-A188 WeakPolarHBondContact O-CB 3.24Å; V185-A188 PolarHBondContact O-N 2.79Å; R186-A188 VanDerWaalsContact C-N 3.27Å; R186-A188 PolarHBondContact O-N 2.93Å; A188-V190 PolarHBondContact O-N 2.97Å; A188-L191 PolarHBondContact O-N 3.37Å; A188-V192 WeakPolarHBondContact O-CG2 3.06Å; A188-V192 PolarHBondContact O-N 3.4Å; A188-M253 HydrophobicContact CB-CE 3.99Å; A188-A265 HydrophobicContact CB-CB 4.05Å; A188-Y269 HydrophobicContact CB-CD1 4.16Å; A188-Y269 HydrophobicContact CB-CG 4.12Å
189F97.8Very high96.8Very high2 Ų252.4 Ų52.41%0.00928%0.282CS..Hα-helixtrans-63-42.1179.2-84.9-100.3000112V185 R186 L191 V192 E193 M224 L227 A228 I231 Y269 F332V185-F189 HydrophobicContact CG1-CD2 4.21Å; V185-F189 HydrophobicContact CG1-CE2 4.26Å; V185-F189 WeakPolarHBondContact O-CD2 3.47Å; V185-F189 PolarHBondContact O-N 3.07Å; V185-F189 VanDerWaalsContact O-N 3.14Å; R186-F189 PolarHBondContact O-N 2.99Å; F189-L191 VanDerWaalsContact C-N 3.31Å; F189-L191 PolarHBondContact O-N 3.21Å; F189-V192 PolarHBondContact O-N 3.16Å; F189-E193 WeakPolarHBondContact O-CB 3.25Å; F189-E193 PolarHBondContact O-N 2.85Å; F189-M224 HydrophobicContact CD1-CE 3.57Å; F189-M224 HydrophobicContact CE1-CE 4.2Å; F189-M224 HydrophobicContact CG-CE 4.45Å; F189-L227 HydrophobicContact CE1-CB 4.06Å; F189-L227 HydrophobicContact CZ-CB 3.99Å; F189-A228 HydrophobicContact CE1-CB 4.19Å; F189-A228 HydrophobicContact CZ-CB 4.32Å; F189-I231 HydrophobicContact CE2-CD1 3.74Å; F189-I231 HydrophobicContact CZ-CD1 4.4Å; F189-Y269 HydrophobicContact CE2-CD1 4.46Å; F189-Y269 AromaticContact CE2-CE1 3.85Å; F189-Y269 HydrophobicContact CE2-CE1 3.85Å; F189-Y269 AromaticContact CE2-CZ 3.97Å; F189-Y269 HydrophobicContact CZ-CE1 4.05Å; F189-F332 HydrophobicContact CD1-CB 3.86Å; F189-F332 HydrophobicContact CD1-CD1 4.28Å; F189-F332 HydrophobicContact CD2-CD1 4.02Å; F189-F332 HydrophobicContact CE1-CB 3.9Å; F189-F332 AromaticContact CE1-CD1 3.89Å; F189-F332 HydrophobicContact CE1-CD1 3.89Å; F189-F332 HydrophobicContact CE1-CG 4.27Å; F189-F332 AromaticContact CE2-CD1 3.63Å; F189-F332 HydrophobicContact CE2-CD1 3.63Å; F189-F332 HydrophobicContact CE2-CE1 4.15Å; F189-F332 HydrophobicContact CG-CB 4.36Å; F189-F332 HydrophobicContact CG-CD1 4.35Å; F189-F332 HydrophobicContact CZ-CB 4.44Å; F189-F332 AromaticContact CZ-CD1 3.55Å; F189-F332 HydrophobicContact CZ-CD1 3.55Å; F189-F332 HydrophobicContact CZ-CE1 4.18Å; F189-F332 HydrophobicContact CZ-CG 4.35Å
190V96.3Very high96.8Very high97 Ų9749 Ų4959%0.58827%0.268SS*.Hα-helixtrans-58.7-42.5173.91710000111.5R186 A188 A194R186-V190 WeakPolarHBondContact O-CG2 3.46Å; R186-V190 PolarHBondContact O-N 2.8Å; R186-V190 VanDerWaalsContact O-N 3.1Å; A188-V190 PolarHBondContact O-N 2.97Å; V190-A194 WeakPolarHBondContact O-CB 3.41Å; V190-A194 PolarHBondContact O-N 3.12Å
191L97Very high96.7Very high56 Ų5646.5 Ų46.529%0.29326%0.257SS..Hα-helixtrans-70.2-36.4179.4-71170.3000112.7E187 A188 F189 T195 A265 Y266E187-L191 HydrophobicContact CG-CD1 4.06Å; E187-L191 WeakPolarHBondContact O-CB 3.37Å; E187-L191 WeakPolarHBondContact O-CG 3.39Å; E187-L191 PolarHBondContact O-N 3.43Å; A188-L191 PolarHBondContact O-N 3.37Å; F189-L191 VanDerWaalsContact C-N 3.31Å; F189-L191 PolarHBondContact O-N 3.21Å; L191-T195 WeakPolarHBondContact O-CB 3.37Å; L191-T195 PolarHBondContact O-N 2.93Å; L191-T195 PolarHBondContact O-OG1 2.88Å; L191-A265 HydrophobicContact CD1-CB 4.22Å; L191-Y266 HydrophobicContact CB-CD2 4.24Å
192V97.1Very high96.6Very high0 Ų051.5 Ų51.50%029%0.288CS..Hα-helixtrans-63.7-48.8174.2175.80000109.7A188 F189 A194 T195 L196 V204 F208 M224 L227 Y266A188-V192 WeakPolarHBondContact O-CG2 3.06Å; A188-V192 PolarHBondContact O-N 3.4Å; F189-V192 PolarHBondContact O-N 3.16Å; V192-A194 PolarHBondContact O-N 2.54Å; V192-T195 WeakPolarHBondContact O-CB 3.23Å; V192-T195 PolarHBondContact O-N 2.79Å; V192-T195 VanDerWaalsContact O-N 3.15Å; V192-L196 HydrophobicContact CG1-CD1 4.36Å; V192-L196 WeakPolarHBondContact O-CG 3.39Å; V192-L196 PolarHBondContact O-N 2.81Å; V192-V204 HydrophobicContact CG1-CG1 4.18Å; V192-F208 HydrophobicContact CG1-CE2 4.46Å; V192-F208 HydrophobicContact CG2-CE2 3.72Å; V192-F208 HydrophobicContact CG2-CZ 3.6Å; V192-M224 HydrophobicContact CB-CE 4.34Å; V192-M224 HydrophobicContact CB-SD 4.43Å; V192-M224 HydrophobicContact CG1-CE 4.17Å; V192-M224 HydrophobicContact CG1-SD 3.63Å; V192-L227 HydrophobicContact CG1-CD1 4.12Å; V192-Y266 HydrophobicContact CB-CE2 4.44Å; V192-Y266 HydrophobicContact CG2-CD2 3.67Å; V192-Y266 HydrophobicContact CG2-CE2 3.77Å
193E95.3Very high96.5Very high56 Ų5656.1 Ų56.126%0.26231%0.308SS..Hα-helixtrans-60.8-46.8179.1-171.1173.9151.600111.9F189 T195 L196 L197 S333 M335F189-E193 WeakPolarHBondContact O-CB 3.25Å; F189-E193 PolarHBondContact O-N 2.85Å; E193-T195 VanDerWaalsContact C-N 3.27Å; E193-T195 PolarHBondContact O-N 2.93Å; E193-L196 WeakPolarHBondContact O-CB 3.3Å; E193-L196 PolarHBondContact O-N 3.05Å; E193-L196 VanDerWaalsContact O-N 3.11Å; E193-L197 HydrophobicContact CG-CD1 4.36Å; E193-L197 WeakPolarHBondContact O-CG 3.41Å; E193-L197 PolarHBondContact O-N 2.97Å; E193-S333 WeakPolarHBondContact OE2-CB 3.36Å; E193-S333 PolarHBondContact OE2-OG 3.25Å; E193-M335 HydrophobicContact CG-SD 4.31Å
194A95.7Very high96.5Very high40 Ų4053.5 Ų53.533%0.33129%0.287SS..Hα-helixtrans-58.2-40.4174.900000112.2V190 V192 L196 L197 D198V190-A194 WeakPolarHBondContact O-CB 3.41Å; V190-A194 PolarHBondContact O-N 3.12Å; V192-A194 PolarHBondContact O-N 2.54Å; A194-L196 VanDerWaalsContact C-N 3.33Å; A194-L196 PolarHBondContact O-N 3.23Å; A194-L197 PolarHBondContact O-N 3.29Å; A194-D198 PolarHBondContact O-N 3.4Å
195T96Very high96.5Very high24 Ų2451.8 Ų51.815%0.14728%0.28CS..Hα-helixtrans-65.4-37.1177.7-55.70000111.7L191 V192 E193 N200 V204L191-T195 WeakPolarHBondContact O-CB 3.37Å; L191-T195 PolarHBondContact O-N 2.93Å; L191-T195 PolarHBondContact O-OG1 2.88Å; V192-T195 WeakPolarHBondContact O-CB 3.23Å; V192-T195 PolarHBondContact O-N 2.79Å; V192-T195 VanDerWaalsContact O-N 3.15Å; E193-T195 VanDerWaalsContact C-N 3.27Å; E193-T195 PolarHBondContact O-N 2.93Å; T195-N200 HydrophobicContact CG2-CB 3.67Å; T195-N200 WeakPolarHBondContact O-CB 3.28Å; T195-N200 PolarHBondContact O-N 2.91Å; T195-N200 VanDerWaalsContact O-N 3.13Å; T195-V204 HydrophobicContact CG2-CG2 3.5Å
196L95.3Very high96.4Very high2 Ų254.5 Ų54.51%0.0131%0.309CS..Hα-helixtrans-66.8-43.9173.2-67.8171.6000111.3V192 E193 A194 D198 G199 F201 V204 P214 Q220 L223 M224V192-L196 HydrophobicContact CG1-CD1 4.36Å; V192-L196 WeakPolarHBondContact O-CG 3.39Å; V192-L196 PolarHBondContact O-N 2.81Å; E193-L196 WeakPolarHBondContact O-CB 3.3Å; E193-L196 PolarHBondContact O-N 3.05Å; E193-L196 VanDerWaalsContact O-N 3.11Å; A194-L196 VanDerWaalsContact C-N 3.33Å; A194-L196 PolarHBondContact O-N 3.23Å; L196-D198 VanDerWaalsContact C-N 3.27Å; L196-D198 PolarHBondContact O-N 2.86Å; L196-G199 WeakPolarHBondContact O-CA 3.43Å; L196-G199 PolarHBondContact O-N 2.82Å; L196-F201 HydrophobicContact CB-CE1 4.47Å; L196-F201 HydrophobicContact CD2-CD1 3.82Å; L196-F201 HydrophobicContact CD2-CE1 4.44Å; L196-F201 WeakPolarHBondContact O-CE1 3.38Å; L196-V204 HydrophobicContact CD2-CB 4.05Å; L196-V204 HydrophobicContact CD2-CG1 4.09Å; L196-V204 HydrophobicContact CD2-CG2 3.92Å; L196-V204 HydrophobicContact CG-CG2 4.27Å; L196-P214 HydrophobicContact CD2-CG 4.29Å; L196-Q220 HydrophobicContact CD1-CB 4.5Å; L196-Q220 HydrophobicContact CD2-CG 4.47Å; L196-L223 HydrophobicContact CD1-CD2 4.14Å; L196-L223 HydrophobicContact CD2-CD2 4.24Å; L196-M224 HydrophobicContact CD1-CG 4.45Å; L196-M224 HydrophobicContact CD1-SD 4Å
197L94.2Very high96.3Very high123 Ų12351.4 Ų51.464%0.64430%0.3SS*.Hα-helixtrans-62.8-32.8178.1-70173.7000112.8E193 A194 G199E193-L197 HydrophobicContact CG-CD1 4.36Å; E193-L197 WeakPolarHBondContact O-CG 3.41Å; E193-L197 PolarHBondContact O-N 2.97Å; A194-L197 PolarHBondContact O-N 3.29Å; L197-G199 PolarHBondContact O-N 2.71Å
198D95.5Very high96.2Very high124 Ų12448 Ų4866%0.66328%0.284SS*.THydrogen-bonded Turntrans-71.9-0.5172.7-72.7-17.4000113.4A194 L196 N200A194-D198 PolarHBondContact O-N 3.4Å; L196-D198 VanDerWaalsContact C-N 3.27Å; L196-D198 PolarHBondContact O-N 2.86Å; D198-N200 VanDerWaalsContact C-N 3.34Å; D198-N200 WeakPolarHBondContact CB-ND2 3.39Å
199G94.9Very high96.1Very high39 Ų3949.2 Ų49.240%0.40230%0.297SS..THydrogen-bonded Turntrans79.311.8179.700000114.4L196 L197 F201L196-G199 WeakPolarHBondContact O-CA 3.43Å; L196-G199 PolarHBondContact O-N 2.82Å; L197-G199 PolarHBondContact O-N 2.71Å; G199-F201 PolarHBondContact O-N 2.94Å
200N96.3Very high96.1Very high76 Ų7650 Ų5041%0.40630%0.302SS..  trans-83.344.5-176.3-66.7-55.8000113T195 D198 T202 K203 V204T195-N200 HydrophobicContact CG2-CB 3.67Å; T195-N200 WeakPolarHBondContact O-CB 3.28Å; T195-N200 PolarHBondContact O-N 2.91Å; T195-N200 VanDerWaalsContact O-N 3.13Å; D198-N200 VanDerWaalsContact C-N 3.34Å; D198-N200 WeakPolarHBondContact CB-ND2 3.39Å; N200-T202 PolarHBondContact O-N 3.24Å; N200-K203 HydrophobicContact CB-CB 4.27Å; N200-K203 WeakPolarHBondContact O-CB 3.46Å; N200-K203 PolarHBondContact O-N 3.19Å; N200-K203 VanDerWaalsContact O-N 3.14Å; N200-V204 PolarHBondContact O-N 2.59Å
201F96.5Very high96Very high53 Ų5348.2 Ų48.223%0.23229%0.294CS..Hα-helixtrans-59.1-43.5-172.9-48.4-55.9000113.6L196 G199 K203 V204 A205 T213L196-F201 HydrophobicContact CB-CE1 4.47Å; L196-F201 HydrophobicContact CD2-CD1 3.82Å; L196-F201 HydrophobicContact CD2-CE1 4.44Å; L196-F201 WeakPolarHBondContact O-CE1 3.38Å; G199-F201 PolarHBondContact O-N 2.94Å; F201-K203 VanDerWaalsContact C-N 3.25Å; F201-K203 PolarHBondContact O-N 2.84Å; F201-V204 PolarHBondContact O-N 2.99Å; F201-A205 WeakPolarHBondContact O-CB 3.27Å; F201-A205 PolarHBondContact O-N 3.27Å; F201-T213 HydrophobicContact CB-CG2 3.48Å; F201-T213 VanDerWaalsContact CB-CG2 3.48Å
202T97Very high95.9Very high106 Ų10648.9 Ų48.965%0.6530%0.295SS*.Hα-helixtrans-63.9-33.6-179.8-56.10000111.9N200 G206N200-T202 PolarHBondContact O-N 3.24Å; T202-G206 PolarHBondContact O-N 3.45Å
203K95.4Very high95.9Very high104 Ų10450.6 Ų50.645%0.45231%0.306SS..Hα-helixtrans-66.3-50.4175.7173.3173.817247.30110.6N200 F201 A205 G206 D207N200-K203 HydrophobicContact CB-CB 4.27Å; N200-K203 WeakPolarHBondContact O-CB 3.46Å; N200-K203 PolarHBondContact O-N 3.19Å; N200-K203 VanDerWaalsContact O-N 3.14Å; F201-K203 VanDerWaalsContact C-N 3.25Å; F201-K203 PolarHBondContact O-N 2.84Å; K203-A205 VanDerWaalsContact C-N 3.31Å; K203-A205 PolarHBondContact O-N 2.91Å; K203-G206 PolarHBondContact O-N 3.18Å; K203-D207 WeakPolarHBondContact CG-OD2 3.48Å; K203-D207 IonicContact NZ-OD1 2.82Å; K203-D207 IonicContact NZ-OD2 2.97Å; K203-D207 PolarHBondContact NZ-OD2 2.66Å; K203-D207 VanDerWaalsContact O-CB 3.26Å; K203-D207 WeakPolarHBondContact O-CB 3.07Å; K203-D207 VanDerWaalsContact O-CG 3.22Å; K203-D207 PolarHBondContact O-N 2.83Å
204V97.1Very high96Very high0 Ų048 Ų480%029%0.293CS..Hα-helixtrans-60-44.8179.3-179.90000110.5V192 T195 L196 N200 F201 G206 D207 F208 L223V192-V204 HydrophobicContact CG1-CG1 4.18Å; T195-V204 HydrophobicContact CG2-CG2 3.5Å; L196-V204 HydrophobicContact CD2-CB 4.05Å; L196-V204 HydrophobicContact CD2-CG1 4.09Å; L196-V204 HydrophobicContact CD2-CG2 3.92Å; L196-V204 HydrophobicContact CG-CG2 4.27Å; N200-V204 PolarHBondContact O-N 2.59Å; F201-V204 PolarHBondContact O-N 2.99Å; V204-G206 PolarHBondContact O-N 2.88Å; V204-D207 PolarHBondContact O-N 3.17Å; V204-F208 HydrophobicContact CG1-CD2 3.85Å; V204-F208 HydrophobicContact CG1-CE2 4.28Å; V204-F208 WeakPolarHBondContact O-CD2 3.43Å; V204-F208 PolarHBondContact O-N 3.07Å; V204-L223 HydrophobicContact CG1-CD2 3.49Å; V204-L223 VanDerWaalsContact CG1-CD2 3.49Å
205A97.3Very high95.6Very high7 Ų753.4 Ų53.46%0.05831%0.31CS..Hα-helixtrans-59.1-46177.400000112.8F201 K203 G209 C210F201-A205 WeakPolarHBondContact O-CB 3.27Å; F201-A205 PolarHBondContact O-N 3.27Å; K203-A205 VanDerWaalsContact C-N 3.31Å; K203-A205 PolarHBondContact O-N 2.91Å; A205-G209 PolarHBondContact O-N 2.94Å; A205-G209 VanDerWaalsContact O-N 3.08Å; A205-C210 HydrophobicContact CB-CB 4.07Å; A205-C210 PolarHBondContact O-N 2.9Å
206G96.8Very high95.5Very high58 Ų5855.2 Ų55.260%0.59832%0.318SS*.Hα-helixtrans-67.6-40177.200000113.1T202 K203 V204T202-G206 PolarHBondContact O-N 3.45Å; K203-G206 PolarHBondContact O-N 3.18Å; V204-G206 PolarHBondContact O-N 2.88Å
207D95.6Very high95.4Very high40 Ų4059.8 Ų59.821%0.21435%0.348CS..Hα-helixtrans-65.1-45-179.2-78.8-18.2000111.3K203 V204 Y266 N270 Q274K203-D207 WeakPolarHBondContact CG-OD2 3.48Å; K203-D207 IonicContact NZ-OD1 2.82Å; K203-D207 IonicContact NZ-OD2 2.97Å; K203-D207 PolarHBondContact NZ-OD2 2.66Å; K203-D207 VanDerWaalsContact O-CB 3.26Å; K203-D207 WeakPolarHBondContact O-CB 3.07Å; K203-D207 VanDerWaalsContact O-CG 3.22Å; K203-D207 PolarHBondContact O-N 2.83Å; V204-D207 PolarHBondContact O-N 3.17Å; D207-Y266 HydrophobicContact CB-CE1 4.18Å; D207-Y266 WeakPolarHBondContact CB-OH 3.48Å; D207-Y266 WeakPolarHBondContact OD2-CE1 3.31Å; D207-Y266 PolarHBondContact OD2-OH 2.88Å; D207-N270 VanDerWaalsContact C-ND2 3.27Å; D207-N270 WeakPolarHBondContact CA-ND2 3.3Å; D207-N270 VanDerWaalsContact CB-ND2 3.29Å; D207-N270 WeakPolarHBondContact CB-ND2 3.33Å; D207-N270 PolarHBondContact O-ND2 3.07Å; D207-N270 PolarHBondContact O-OD1 2.78Å; D207-Q274 PolarHBondContact O-NE2 3.25Å
208F96.3Very high95.4Very high0 Ų056.8 Ų56.80%033%0.333CS..THydrogen-bonded Turntrans-94.17.1-178.2-69.2-81.8000114.4V192 V204 C210 L227 Y266 Y269 N270 V273V192-F208 HydrophobicContact CG1-CE2 4.46Å; V192-F208 HydrophobicContact CG2-CE2 3.72Å; V192-F208 HydrophobicContact CG2-CZ 3.6Å; V204-F208 HydrophobicContact CG1-CD2 3.85Å; V204-F208 HydrophobicContact CG1-CE2 4.28Å; V204-F208 WeakPolarHBondContact O-CD2 3.43Å; V204-F208 PolarHBondContact O-N 3.07Å; F208-C210 PolarHBondContact O-N 3.37Å; F208-L227 HydrophobicContact CB-CD2 4.47Å; F208-L227 HydrophobicContact CD1-CD1 4.44Å; F208-L227 HydrophobicContact CD1-CD2 3.54Å; F208-L227 HydrophobicContact CE1-CD1 4.44Å; F208-L227 HydrophobicContact CE1-CD2 3.96Å; F208-L227 HydrophobicContact CG-CD2 4.1Å; F208-Y266 HydrophobicContact CE2-CD2 4.45Å; F208-Y266 HydrophobicContact CE2-CE1 4.37Å; F208-Y266 AromaticContact CE2-CE2 3.75Å; F208-Y266 HydrophobicContact CE2-CE2 3.75Å; F208-Y266 AromaticContact CE2-CZ 3.7Å; F208-Y266 HydrophobicContact CZ-CE2 4.3Å; F208-Y269 AromaticContact CE1-CD1 3.69Å; F208-Y269 HydrophobicContact CE1-CD1 3.69Å; F208-Y269 AromaticContact CE1-CE1 3.92Å; F208-Y269 HydrophobicContact CE1-CE1 3.92Å; F208-Y269 HydrophobicContact CE1-CG 4.4Å; F208-Y269 AromaticContact CZ-CD1 4Å; F208-Y269 HydrophobicContact CZ-CD1 4Å; F208-Y269 HydrophobicContact CZ-CE1 4.45Å; F208-N270 HydrophobicContact CE1-CB 4.11Å; F208-N270 HydrophobicContact CZ-CB 4.29Å; F208-V273 HydrophobicContact CD1-CB 4.06Å; F208-V273 HydrophobicContact CD1-CG1 4.07Å; F208-V273 HydrophobicContact CD1-CG2 3.94Å; F208-V273 HydrophobicContact CE1-CG2 4.09Å
209G95.3Very high95.4Very high26 Ų2651.3 Ų51.327%0.26830%0.304SS..THydrogen-bonded Turntrans65.836.9175.800000113.8A205 C284 L285A205-G209 PolarHBondContact O-N 2.94Å; A205-G209 VanDerWaalsContact O-N 3.08Å; G209-C284 CarbonylContact O-C 3.59Å; G209-C284 VanDerWaalsContact O-CA 3.29Å; G209-C284 WeakPolarHBondContact O-CA 3.42Å; G209-C284 VanDerWaalsContact O-CB 3.24Å; G209-C284 WeakPolarHBondContact O-CB 3.44Å; G209-L285 PolarHBondContact O-N 3.2Å
210C96.4Very high95.4Very high18 Ų1850.5 Ų50.512%0.12229%0.289CS..BIsolated β-bridgetrans-70.4143.9-179.8-55.20000111.9A205 F208 Q212 L285 V287A205-C210 HydrophobicContact CB-CB 4.07Å; A205-C210 PolarHBondContact O-N 2.9Å; F208-C210 PolarHBondContact O-N 3.37Å; C210-Q212 WeakPolarHBondContact CB-O 3.46Å; C210-Q212 PolarHBondContact O-N 2.98Å; C210-L285 CarbonylContact C-O 3.51Å; C210-L285 VanDerWaalsContact CA-O 3.25Å; C210-L285 WeakPolarHBondContact CA-O 3.47Å; C210-V287 HydrophobicContact CB-CG1 4.26Å; C210-V287 HydrophobicContact CB-CG2 4.03Å
211C95.3Very high95.3Very high61 Ų6147.8 Ų47.841%0.41227%0.274SS..SBendtrans-64.2-26.6175.8-570000112.2C284 L285C211-C284 WeakPolarHBondContact CA-SG 3.41Å; C211-C284 HydrophobicContact CB-CB 3.98Å; C211-C284 WeakPolarHBondContact CB-SG 3.38Å; C211-C284 WeakPolarHBondContact SG-CB 3.3Å; C211-C284 PolarHBondContact SG-O 3.25Å; C211-C284 CovalentContact SG-SG 2.03Å; C211-C284 PolarHBondContact SG-SG 3.05Å; C211-L285 PolarHBondContact N-O 2.96Å; C211-L285 VanDerWaalsContact SG-C 3.52Å
212Q95.4Very high95.3Very high70 Ų7046.3 Ų46.333%0.32727%0.268SS..SBendtrans-145.2167.4176.466174.823.500111.9C210 V287 S288C210-Q212 WeakPolarHBondContact CB-O 3.46Å; C210-Q212 PolarHBondContact O-N 2.98Å; Q212-V287 HydrophobicContact CG-CG2 3.86Å; Q212-S288 VanDerWaalsContact CD-CB 3.49Å; Q212-S288 PolarHBondContact NE2-OG 3.05Å
213T97.1Very high95.3Very high36 Ų3641.2 Ų41.222%0.22124%0.237CC..  trans-79.1127.2172.2-57.70000110.2F201 K215F201-T213 HydrophobicContact CB-CG2 3.48Å; F201-T213 VanDerWaalsContact CB-CG2 3.48Å; T213-K215 HydrophobicContact CG2-CG 3.98Å; T213-K215 PolarHBondContact O-N 3.46Å
214P95.8Very high95.4Very high0 Ų036.3 Ų36.30%022%0.215CC..  trans-7885.3-179.932.3-35.3000110.6L196 D219 Q220 L223 V287L196-P214 HydrophobicContact CD2-CG 4.29Å; P214-D219 HydrophobicContact CB-CB 3.79Å; P214-Q220 HydrophobicContact CB-CG 4.14Å; P214-Q220 WeakPolarHBondContact O-CG 3.41Å; P214-L223 HydrophobicContact CG-CD2 3.94Å; P214-V287 HydrophobicContact CB-CG2 4.23Å
215K88Confident95.3Very high155 Ų15537.5 Ų37.567%0.67422%0.221SC*.  trans-84-30.7-169.6-70177.9-174.9175.50113.2T213T213-K215 HydrophobicContact CG2-CG 3.98Å; T213-K215 PolarHBondContact O-N 3.46Å
216N93.5Very high95.3Very high62 Ų6238.5 Ų38.533%0.33223%0.226SC..SBendtrans-107.9162.3-176.773.664.3000110.9D218 D219 Q220N216-D218 VanDerWaalsContact C-N 3.29Å; N216-D218 PolarHBondContact O-N 3.47Å; N216-D218 WeakPolarHBondContact OD1-CA 3.42Å; N216-D218 WeakPolarHBondContact OD1-CB 3.41Å; N216-D218 PolarHBondContact OD1-N 2.87Å; N216-D219 PolarHBondContact ND2-OD1 3.49Å; N216-D219 PolarHBondContact ND2-OD2 2.95Å; N216-D219 PolarHBondContact O-N 2.66Å; N216-D219 PolarHBondContact OD1-N 2.98Å; N216-Q220 WeakPolarHBondContact O-CG 3.43Å; N216-Q220 PolarHBondContact O-N 2.71Å
217P93.6Very high95.3Very high98 Ų9835.8 Ų35.864%0.63620%0.197SC*.Hα-helixtrans-59.5-33.7-178.1-27.336.5000114.8Q220 M221P217-Q220 PolarHBondContact O-N 2.98Å; P217-M221 PolarHBondContact O-N 3.44Å
218D93.9Very high95.4Very high59 Ų5934 Ų3432%0.31619%0.188SC..Hα-helixtrans-69.9-41.7179-62.5-40.3000110.3N216 Q220 M221 E222 H289N216-D218 VanDerWaalsContact C-N 3.29Å; N216-D218 PolarHBondContact O-N 3.47Å; N216-D218 WeakPolarHBondContact OD1-CA 3.42Å; N216-D218 WeakPolarHBondContact OD1-CB 3.41Å; N216-D218 PolarHBondContact OD1-N 2.87Å; D218-Q220 VanDerWaalsContact C-N 3.31Å; D218-Q220 PolarHBondContact O-N 3.14Å; D218-M221 PolarHBondContact O-N 3.48Å; D218-E222 PolarHBondContact O-N 2.98Å; D218-H289 HydrophobicContact CB-CB 3.77Å
219D95.8Very high95.3Very high10 Ų1036.9 Ų36.95%0.05320%0.204CC..Hα-helixtrans-64.3-35173.4-63.7-12.9000112.4P214 N216 E222 L223 V287 H289P214-D219 HydrophobicContact CB-CB 3.79Å; N216-D219 PolarHBondContact ND2-OD1 3.49Å; N216-D219 PolarHBondContact ND2-OD2 2.95Å; N216-D219 PolarHBondContact O-N 2.66Å; N216-D219 PolarHBondContact OD1-N 2.98Å; D219-E222 PolarHBondContact O-N 3.24Å; D219-L223 PolarHBondContact O-N 3.03Å; D219-V287 WeakPolarHBondContact CA-O 3.23Å; D219-V287 WeakPolarHBondContact CB-O 3.16Å; D219-H289 PolarHBondContact OD1-N 3.26Å; D219-H289 VanDerWaalsContact OD1-N 3.16Å
220Q95.8Very high95.4Very high21 Ų2136 Ų3610%0.09819%0.193CC..Hα-helixtrans-67.8-41.7177-70.7169.122.900110.9L196 P214 N216 P217 D218 L223 M224L196-Q220 HydrophobicContact CD1-CB 4.5Å; L196-Q220 HydrophobicContact CD2-CG 4.47Å; P214-Q220 HydrophobicContact CB-CG 4.14Å; P214-Q220 WeakPolarHBondContact O-CG 3.41Å; N216-Q220 WeakPolarHBondContact O-CG 3.43Å; N216-Q220 PolarHBondContact O-N 2.71Å; P217-Q220 PolarHBondContact O-N 2.98Å; D218-Q220 VanDerWaalsContact C-N 3.31Å; D218-Q220 PolarHBondContact O-N 3.14Å; Q220-L223 WeakPolarHBondContact O-CB 2.91Å; Q220-L223 PolarHBondContact O-N 3.2Å; Q220-M224 WeakPolarHBondContact O-CG 3.35Å; Q220-M224 PolarHBondContact O-N 3.21Å
221M94.3Very high95.4Very high19 Ų1935.1 Ų35.19%0.09419%0.187CC..Hα-helixtrans-62.5-44.9172.1179.1-150.565.800111.1P217 D218 L223 M224 Q225 A340P217-M221 PolarHBondContact O-N 3.44Å; D218-M221 PolarHBondContact O-N 3.48Å; M221-L223 VanDerWaalsContact C-N 3.29Å; M221-L223 PolarHBondContact O-N 2.66Å; M221-M224 PolarHBondContact O-N 3.13Å; M221-Q225 WeakPolarHBondContact O-CB 3.23Å; M221-Q225 PolarHBondContact O-N 2.96Å; M221-A340 HydrophobicContact CE-CB 4.29Å; M221-A340 HydrophobicContact SD-CB 3.16Å; M221-A340 WeakPolarHBondContact SD-CB 3.31Å
222E95.7Very high95.5Very high22 Ų2232.4 Ų32.410%0.10317%0.168CC..Hα-helixtrans-56.8-44.3177.1-156.483.1-170.400110.9D218 D219 Q225 N226 H289 T292D218-E222 PolarHBondContact O-N 2.98Å; D219-E222 PolarHBondContact O-N 3.24Å; E222-Q225 PolarHBondContact O-N 3.25Å; E222-N226 WeakPolarHBondContact O-CB 3.49Å; E222-N226 PolarHBondContact O-N 3.09Å; E222-N226 PolarHBondContact O-ND2 3.29Å; E222-H289 IonicContact OE2-CG 3.86Å; E222-H289 IonicContact OE2-ND1 3.82Å; E222-H289 PolarHBondContact OE2-ND1 3.38Å; E222-T292 WeakPolarHBondContact OE1-CB 3.39Å; E222-T292 WeakPolarHBondContact OE1-CG2 3.43Å; E222-T292 PolarHBondContact OE1-OG1 2.95Å
223L96.9Very high95.5Very high0 Ų029.6 Ų29.60%016%0.158CC..Hα-helixtrans-57.3-50.8171.916966.3000111.7L196 V204 P214 D219 Q220 M221 Q225 N226 L227 L285 V287L196-L223 HydrophobicContact CD1-CD2 4.14Å; L196-L223 HydrophobicContact CD2-CD2 4.24Å; V204-L223 HydrophobicContact CG1-CD2 3.49Å; V204-L223 VanDerWaalsContact CG1-CD2 3.49Å; P214-L223 HydrophobicContact CG-CD2 3.94Å; D219-L223 PolarHBondContact O-N 3.03Å; Q220-L223 WeakPolarHBondContact O-CB 2.91Å; Q220-L223 PolarHBondContact O-N 3.2Å; M221-L223 VanDerWaalsContact C-N 3.29Å; M221-L223 PolarHBondContact O-N 2.66Å; L223-Q225 VanDerWaalsContact C-N 3.32Å; L223-Q225 PolarHBondContact O-N 3.27Å; L223-N226 PolarHBondContact O-N 3.48Å; L223-L227 HydrophobicContact CD1-CD1 3.78Å; L223-L227 HydrophobicContact CD1-CD2 4.47Å; L223-L227 HydrophobicContact CD1-CG 3.9Å; L223-L227 HydrophobicContact CG-CD1 4.03Å; L223-L227 HydrophobicContact CG-CG 4.46Å; L223-L227 WeakPolarHBondContact O-CB 3.46Å; L223-L227 VanDerWaalsContact O-CG 3.27Å; L223-L227 WeakPolarHBondContact O-CG 3.35Å; L223-L227 PolarHBondContact O-N 3.24Å; L223-L285 HydrophobicContact CD1-CD2 3.98Å; L223-V287 HydrophobicContact CB-CB 4.17Å; L223-V287 HydrophobicContact CB-CG1 3.85Å; L223-V287 HydrophobicContact CD1-CG1 3.9Å; L223-V287 HydrophobicContact CG-CG1 4.48Å
224M96.7Very high95.4Very high0 Ų027.9 Ų27.90%015%0.147CC..Hα-helixtrans-65.5-36-177-65.6-49-73.800112.4F189 V192 L196 Q220 M221 L227 A228 M335 V336F189-M224 HydrophobicContact CD1-CE 3.57Å; F189-M224 HydrophobicContact CE1-CE 4.2Å; F189-M224 HydrophobicContact CG-CE 4.45Å; V192-M224 HydrophobicContact CB-CE 4.34Å; V192-M224 HydrophobicContact CB-SD 4.43Å; V192-M224 HydrophobicContact CG1-CE 4.17Å; V192-M224 HydrophobicContact CG1-SD 3.63Å; L196-M224 HydrophobicContact CD1-CG 4.45Å; L196-M224 HydrophobicContact CD1-SD 4Å; Q220-M224 WeakPolarHBondContact O-CG 3.35Å; Q220-M224 PolarHBondContact O-N 3.21Å; M221-M224 PolarHBondContact O-N 3.13Å; M224-L227 HydrophobicContact SD-CD1 4.38Å; M224-A228 WeakPolarHBondContact O-CB 3.32Å; M224-A228 PolarHBondContact O-N 2.72Å; M224-M335 HydrophobicContact CG-SD 3.85Å; M224-V336 HydrophobicContact CB-CG2 4.39Å
225Q96.2Very high95.5Very high25 Ų2527.9 Ų27.912%0.11715%0.147CC..Hα-helixtrans-63.2-52.9172.5-179.166.965.100110.6M221 E222 L223 L227 A228 D229 V336M221-Q225 WeakPolarHBondContact O-CB 3.23Å; M221-Q225 PolarHBondContact O-N 2.96Å; E222-Q225 PolarHBondContact O-N 3.25Å; L223-Q225 VanDerWaalsContact C-N 3.32Å; L223-Q225 PolarHBondContact O-N 3.27Å; Q225-L227 VanDerWaalsContact C-N 3.27Å; Q225-L227 PolarHBondContact O-N 3.27Å; Q225-A228 CarbonylContact O-C 3.54Å; Q225-A228 WeakPolarHBondContact O-CA 3.4Å; Q225-A228 WeakPolarHBondContact O-CB 3.29Å; Q225-A228 PolarHBondContact O-N 3.37Å; Q225-D229 PolarHBondContact NE2-OD1 3.22Å; Q225-D229 VanDerWaalsContact O-CG 3.26Å; Q225-D229 PolarHBondContact O-N 3.46Å; Q225-V336 HydrophobicContact CB-CG2 4.43Å
226N95.9Very high95.9Very high29 Ų2921.3 Ų21.316%0.15512%0.119CC..Hα-helixtrans-60.6-37.4-178.5-72.3-10.2000112.6E222 L223 D229 I230 L285 D286E222-N226 WeakPolarHBondContact O-CB 3.49Å; E222-N226 PolarHBondContact O-N 3.09Å; E222-N226 PolarHBondContact O-ND2 3.29Å; L223-N226 PolarHBondContact O-N 3.48Å; N226-D229 PolarHBondContact O-N 3.43Å; N226-I230 WeakPolarHBondContact O-CG1 3.42Å; N226-I230 PolarHBondContact O-N 2.74Å; N226-L285 HydrophobicContact CB-CD1 3.77Å; N226-L285 HydrophobicContact CB-CD2 4.05Å; N226-L285 HydrophobicContact CB-CG 4.12Å; N226-D286 PolarHBondContact ND2-O 2.87Å
227L97.4Very high96Very high0 Ų023 Ų230%012%0.121CC..Hα-helixtrans-63.3-47.3172.1-71.8179.9000110.9F189 V192 F208 L223 M224 Q225 D229 I230 Y269 V273 L285F189-L227 HydrophobicContact CE1-CB 4.06Å; F189-L227 HydrophobicContact CZ-CB 3.99Å; V192-L227 HydrophobicContact CG1-CD1 4.12Å; F208-L227 HydrophobicContact CB-CD2 4.47Å; F208-L227 HydrophobicContact CD1-CD1 4.44Å; F208-L227 HydrophobicContact CD1-CD2 3.54Å; F208-L227 HydrophobicContact CE1-CD1 4.44Å; F208-L227 HydrophobicContact CE1-CD2 3.96Å; F208-L227 HydrophobicContact CG-CD2 4.1Å; L223-L227 HydrophobicContact CD1-CD1 3.78Å; L223-L227 HydrophobicContact CD1-CD2 4.47Å; L223-L227 HydrophobicContact CD1-CG 3.9Å; L223-L227 HydrophobicContact CG-CD1 4.03Å; L223-L227 HydrophobicContact CG-CG 4.46Å; L223-L227 WeakPolarHBondContact O-CB 3.46Å; L223-L227 VanDerWaalsContact O-CG 3.27Å; L223-L227 WeakPolarHBondContact O-CG 3.35Å; L223-L227 PolarHBondContact O-N 3.24Å; M224-L227 HydrophobicContact SD-CD1 4.38Å; Q225-L227 VanDerWaalsContact C-N 3.27Å; Q225-L227 PolarHBondContact O-N 3.27Å; L227-D229 VanDerWaalsContact C-N 3.3Å; L227-D229 PolarHBondContact O-N 2.88Å; L227-I230 PolarHBondContact O-N 3.43Å; L227-Y269 WeakPolarHBondContact CA-OH 3.34Å; L227-Y269 HydrophobicContact CB-CE1 4.04Å; L227-Y269 VanDerWaalsContact CB-OH 3.24Å; L227-Y269 WeakPolarHBondContact CB-OH 3.29Å; L227-Y269 HydrophobicContact CD1-CE1 4.23Å; L227-Y269 HydrophobicContact CD2-CE1 3.92Å; L227-Y269 HydrophobicContact CG-CE1 4.27Å; L227-Y269 PolarHBondContact O-OH 2.94Å; L227-V273 HydrophobicContact CD2-CG1 4.49Å; L227-V273 HydrophobicContact CD2-CG2 3.91Å; L227-L285 HydrophobicContact CD2-CD2 4.21Å
228A97.4Very high96Very high2 Ų218.5 Ų18.52%0.0179%0.092CC..Hα-helixtrans-57.9-44.217500000111.4F189 M224 Q225 I230 I231 M232 F332F189-A228 HydrophobicContact CE1-CB 4.19Å; F189-A228 HydrophobicContact CZ-CB 4.32Å; M224-A228 WeakPolarHBondContact O-CB 3.32Å; M224-A228 PolarHBondContact O-N 2.72Å; Q225-A228 CarbonylContact O-C 3.54Å; Q225-A228 WeakPolarHBondContact O-CA 3.4Å; Q225-A228 WeakPolarHBondContact O-CB 3.29Å; Q225-A228 PolarHBondContact O-N 3.37Å; A228-I230 VanDerWaalsContact C-N 3.28Å; A228-I230 PolarHBondContact O-N 2.79Å; A228-I231 PolarHBondContact O-N 3.44Å; A228-M232 HydrophobicContact CB-SD 3.83Å; A228-M232 WeakPolarHBondContact O-CB 3.41Å; A228-M232 WeakPolarHBondContact O-CG 3.34Å; A228-M232 PolarHBondContact O-N 3.19Å; A228-F332 HydrophobicContact CB-CB 4.15Å; A228-F332 HydrophobicContact CB-CD1 4.11Å; A228-F332 HydrophobicContact CB-CD2 3.86Å; A228-F332 HydrophobicContact CB-CE1 4.45Å; A228-F332 HydrophobicContact CB-CE2 4.22Å; A228-F332 HydrophobicContact CB-CG 3.78Å; A228-F332 HydrophobicContact CB-CZ 4.48Å
229D95.7Very high95.9Very high62 Ų6219.2 Ų19.233%0.3329%0.093SC..Hα-helixtrans-58.6-36-179.4-70.2-15.1000112.9Q225 N226 L227 I231 M232 G233Q225-D229 PolarHBondContact NE2-OD1 3.22Å; Q225-D229 VanDerWaalsContact O-CG 3.26Å; Q225-D229 PolarHBondContact O-N 3.46Å; N226-D229 PolarHBondContact O-N 3.43Å; L227-D229 VanDerWaalsContact C-N 3.3Å; L227-D229 PolarHBondContact O-N 2.88Å; D229-I231 VanDerWaalsContact C-N 3.34Å; D229-I231 PolarHBondContact O-N 2.88Å; D229-M232 PolarHBondContact O-N 3.33Å; D229-G233 PolarHBondContact O-N 3.46Å
230I95.8Very high95.6Very high7 Ų719.4 Ų19.44%0.0369%0.094CC..Hα-helixtrans-60-44.8174.1-71.4168.5000110.8N226 L227 A228 S234 Y272 V273 Y276N226-I230 WeakPolarHBondContact O-CG1 3.42Å; N226-I230 PolarHBondContact O-N 2.74Å; L227-I230 PolarHBondContact O-N 3.43Å; A228-I230 VanDerWaalsContact C-N 3.28Å; A228-I230 PolarHBondContact O-N 2.79Å; I230-S234 PolarHBondContact O-N 3.41Å; I230-S234 PolarHBondContact O-OG 2.62Å; I230-Y272 HydrophobicContact CG2-CD1 4.17Å; I230-Y272 HydrophobicContact CG2-CE1 3.76Å; I230-V273 HydrophobicContact CD1-CB 4.44Å; I230-V273 HydrophobicContact CD1-CG1 3.92Å; I230-V273 HydrophobicContact CD1-CG2 3.99Å; I230-Y276 HydrophobicContact CD1-CD1 4.26Å; I230-Y276 HydrophobicContact CG1-CD1 3.94Å; I230-Y276 HydrophobicContact CG1-CE1 3.94Å; I230-Y276 HydrophobicContact CG1-CG 4.39Å; I230-Y276 HydrophobicContact CG2-CD1 4.18Å; I230-Y276 HydrophobicContact CG2-CD2 3.81Å; I230-Y276 HydrophobicContact CG2-CE2 4.25Å; I230-Y276 HydrophobicContact CG2-CG 3.77Å
231I97.3Very high94.7Very high0 Ų022 Ų220%013%0.127CC..Hα-helixtrans-74.1-42.7178.4-65.5-174.4000111.1V166 L170 V185 F189 A228 D229 G233 S234 V235 L249 Y269 F332V166-I231 HydrophobicContact CG1-CG2 4.11Å; L170-I231 HydrophobicContact CD1-CG2 4.08Å; L170-I231 HydrophobicContact CD2-CG2 4.34Å; V185-I231 HydrophobicContact CB-CD1 4.46Å; V185-I231 HydrophobicContact CG1-CD1 3.54Å; V185-I231 HydrophobicContact CG2-CD1 4.08Å; F189-I231 HydrophobicContact CE2-CD1 3.74Å; F189-I231 HydrophobicContact CZ-CD1 4.4Å; A228-I231 PolarHBondContact O-N 3.44Å; D229-I231 VanDerWaalsContact C-N 3.34Å; D229-I231 PolarHBondContact O-N 2.88Å; I231-G233 VanDerWaalsContact C-N 3.34Å; I231-G233 PolarHBondContact O-N 2.98Å; I231-S234 PolarHBondContact O-N 3.14Å; I231-V235 PolarHBondContact O-N 2.66Å; I231-L249 HydrophobicContact CB-CD2 4.48Å; I231-L249 HydrophobicContact CG1-CD1 4.47Å; I231-L249 HydrophobicContact CG1-CD2 4.3Å; I231-L249 HydrophobicContact CG2-CD2 3.86Å; I231-Y269 HydrophobicContact CD1-CD2 4.19Å; I231-Y269 HydrophobicContact CD1-CE2 3.61Å; I231-Y269 HydrophobicContact CG1-CE2 3.77Å; I231-F332 HydrophobicContact CB-CE1 3.9Å; I231-F332 HydrophobicContact CB-CZ 4.12Å; I231-F332 HydrophobicContact CD1-CE1 4.1Å; I231-F332 HydrophobicContact CG2-CE1 3.81Å; I231-F332 HydrophobicContact CG2-CZ 3.89Å
232M97.1Very high93.5Very high4 Ų427 Ų272%0.0216%0.158CC..Hα-helixtrans-58.5-46.1178.4-71.516456.700110.8Y162 V166 A228 D229 S234 V235 Q236 Q323 F332Y162-M232 HydrophobicContact CD1-CE 3.57Å; Y162-M232 HydrophobicContact CD1-CG 4.42Å; Y162-M232 HydrophobicContact CE1-CB 3.81Å; Y162-M232 HydrophobicContact CE1-CE 3.23Å; Y162-M232 HydrophobicContact CE1-CG 3.76Å; Y162-M232 HydrophobicContact CE1-SD 4.21Å; V166-M232 HydrophobicContact CG1-CG 4.38Å; V166-M232 HydrophobicContact CG2-CB 4.48Å; V166-M232 HydrophobicContact CG2-CG 4.13Å; A228-M232 HydrophobicContact CB-SD 3.83Å; A228-M232 WeakPolarHBondContact O-CB 3.41Å; A228-M232 WeakPolarHBondContact O-CG 3.34Å; A228-M232 PolarHBondContact O-N 3.19Å; D229-M232 PolarHBondContact O-N 3.33Å; M232-S234 PolarHBondContact O-N 3.25Å; M232-V235 PolarHBondContact O-N 2.95Å; M232-Q236 WeakPolarHBondContact O-CB 3.16Å; M232-Q236 PolarHBondContact O-N 2.88Å; M232-Q323 HydrophobicContact CE-CB 3.88Å; M232-Q323 HydrophobicContact CE-CG 4.18Å; M232-F332 HydrophobicContact CG-CE2 3.6Å; M232-F332 HydrophobicContact CG-CZ 3.77Å; M232-F332 HydrophobicContact SD-CD2 4.42Å; M232-F332 HydrophobicContact SD-CE2 3.86Å; M232-F332 HydrophobicContact SD-CZ 4.47Å
233G95.4Very high92.7Very high11 Ų1128.2 Ų28.211%0.11317%0.165CC..Hα-helixtrans-60.9-41.2175.400000112.9D229 I231 V235 Q236 Y237D229-G233 PolarHBondContact O-N 3.46Å; I231-G233 VanDerWaalsContact C-N 3.34Å; I231-G233 PolarHBondContact O-N 2.98Å; G233-V235 VanDerWaalsContact C-N 3.3Å; G233-V235 PolarHBondContact O-N 3.38Å; G233-Q236 PolarHBondContact O-N 3.16Å; G233-Y237 WeakPolarHBondContact O-CB 3.42Å; G233-Y237 PolarHBondContact O-N 3.17Å
234S95.8Very high92.4Very high0 Ų028.8 Ų28.80%017%0.167CC..Hα-helixtrans-66.7-28.1176.3-76.90000114.6I230 I231 M232 N238 M244 Y272I230-S234 PolarHBondContact O-N 3.41Å; I230-S234 PolarHBondContact O-OG 2.62Å; I231-S234 PolarHBondContact O-N 3.14Å; M232-S234 PolarHBondContact O-N 3.25Å; S234-N238 WeakPolarHBondContact O-CA 3.17Å; S234-N238 WeakPolarHBondContact O-CB 3.47Å; S234-N238 PolarHBondContact O-N 2.87Å; S234-M244 VanDerWaalsContact CA-O 3.3Å; S234-M244 WeakPolarHBondContact CA-O 3.31Å; S234-M244 WeakPolarHBondContact CB-O 3.09Å; S234-M244 PolarHBondContact OG-O 2.69Å; S234-Y272 WeakPolarHBondContact CB-OH 3.32Å; S234-Y272 PolarHBondContact OG-OH 3.13Å
235V97.1Very high92.3Very high0 Ų029.4 Ų29.40%017%0.172CC..Hα-helixtrans-80.8-50.9171.3174.20000111.1V166 L170 I231 M232 G233 Y237 N238 I246 V384 P386V166-V235 HydrophobicContact CG1-CB 4.23Å; V166-V235 HydrophobicContact CG1-CG2 3.89Å; V166-V235 HydrophobicContact CG2-CB 4.35Å; V166-V235 HydrophobicContact CG2-CG1 4.35Å; L170-V235 HydrophobicContact CD2-CG2 3.97Å; L170-V235 HydrophobicContact CG-CG2 4.29Å; I231-V235 PolarHBondContact O-N 2.66Å; M232-V235 PolarHBondContact O-N 2.95Å; G233-V235 VanDerWaalsContact C-N 3.3Å; G233-V235 PolarHBondContact O-N 3.38Å; V235-Y237 VanDerWaalsContact C-N 3.26Å; V235-Y237 PolarHBondContact O-N 2.73Å; V235-N238 WeakPolarHBondContact O-CB 3.44Å; V235-N238 PolarHBondContact O-N 3.48Å; V235-I246 HydrophobicContact CB-CD1 4.29Å; V235-I246 HydrophobicContact CB-CG1 4.42Å; V235-I246 HydrophobicContact CG1-CD1 4.11Å; V235-I246 HydrophobicContact CG2-CD1 4.01Å; V235-I246 HydrophobicContact CG2-CG1 3.86Å; V235-V384 WeakPolarHBondContact CG1-O 3.36Å; V235-P386 HydrophobicContact CG1-CG 4.48Å
236Q96.7Very high92.3Very high17 Ų1728.2 Ų28.28%0.07917%0.166CC..Hα-helixtrans-56.9-40.2-178-178.4177.3-5300111.7Y162 M232 G233 A409 H410Y162-Q236 PolarHBondContact OH-OE1 2.98Å; M232-Q236 WeakPolarHBondContact O-CB 3.16Å; M232-Q236 PolarHBondContact O-N 2.88Å; G233-Q236 PolarHBondContact O-N 3.16Å; Q236-A409 WeakPolarHBondContact O-CB 3.39Å; Q236-H410 HydrophobicContact CG-CB 3.58Å; Q236-H410 WeakPolarHBondContact O-CB 3.47Å; Q236-H410 PolarHBondContact O-N 2.91Å
237Y94.8Very high92.3Very high97 Ų9733.4 Ų33.438%0.3819%0.188SC..THydrogen-bonded Turntrans-110.430-179.4-59.8-70.3000112.6G233 V235 E239 E240 L243G233-Y237 WeakPolarHBondContact O-CB 3.42Å; G233-Y237 PolarHBondContact O-N 3.17Å; V235-Y237 VanDerWaalsContact C-N 3.26Å; V235-Y237 PolarHBondContact O-N 2.73Å; Y237-E239 PolarHBondContact O-N 3.12Å; Y237-E239 VanDerWaalsContact O-N 3.11Å; Y237-E240 PolarHBondContact O-N 3.09Å; Y237-L243 HydrophobicContact CD2-CD1 3.7Å; Y237-L243 HydrophobicContact CG-CD1 4.29Å
238N95.1Very high92.3Very high3 Ų338.1 Ų38.12%0.01621%0.209CC..THydrogen-bonded Turntrans-52.7120.6-178.817769.9000112.4S234 V235 E240 S245 I246 A409S234-N238 WeakPolarHBondContact O-CA 3.17Å; S234-N238 WeakPolarHBondContact O-CB 3.47Å; S234-N238 PolarHBondContact O-N 2.87Å; V235-N238 WeakPolarHBondContact O-CB 3.44Å; V235-N238 PolarHBondContact O-N 3.48Å; N238-E240 PolarHBondContact O-N 3.05Å; N238-S245 WeakPolarHBondContact OD1-CB 3.28Å; N238-I246 HydrophobicContact CB-CD1 3.78Å; N238-I246 HydrophobicContact CB-CG1 3.92Å; N238-I246 WeakPolarHBondContact OD1-CB 3.35Å; N238-I246 WeakPolarHBondContact OD1-CG1 3.49Å; N238-I246 PolarHBondContact OD1-N 3.37Å; N238-A409 HydrophobicContact CB-CB 4.11Å; N238-A409 WeakPolarHBondContact O-CB 3.03Å
239E91.9Very high92.3Very high74 Ų7438 Ų3835%0.34621%0.209SC..THydrogen-bonded Turntrans64.19.3-177.7-58.4170.7-177.200114.6Y237 R422Y237-E239 PolarHBondContact O-N 3.12Å; Y237-E239 VanDerWaalsContact O-N 3.11Å; E239-R422 IonicContact OE1-CZ 3.17Å; E239-R422 IonicContact OE1-NE 2.71Å; E239-R422 IonicContact OE1-NH2 3.78Å; E239-R422 PolarHBondContact OE1-NH2 2.93Å; E239-R422 IonicContact OE2-CZ 2.66Å; E239-R422 IonicContact OE2-NE 2.78Å; E239-R422 PolarHBondContact OE2-NE 3.36Å; E239-R422 IonicContact OE2-NH2 3.4Å
240E88.2Confident92.4Very high15 Ų1535.2 Ų35.27%0.0719%0.194CC..SBendtrans-114.2139.5176.5-60.3-53.6144.900111.6Y237 N238 A409 A412 S415 R418Y237-E240 PolarHBondContact O-N 3.09Å; N238-E240 PolarHBondContact O-N 3.05Å; E240-A409 HydrophobicContact CG-CB 4.22Å; E240-A412 HydrophobicContact CG-CB 3.64Å; E240-A412 WeakPolarHBondContact OE1-CB 3.02Å; E240-S415 PolarHBondContact OE2-OG 3.14Å; E240-R418 VanDerWaalsContact CD-NH2 3.26Å; E240-R418 IonicContact OE1-CZ 3.25Å; E240-R418 IonicContact OE1-NH1 3.13Å; E240-R418 IonicContact OE1-NH2 2.62Å; E240-R418 PolarHBondContact OE1-NH2 3.37Å; E240-R418 IonicContact OE2-CZ 3.51Å; E240-R418 IonicContact OE2-NH1 3.56Å; E240-R418 PolarHBondContact OE2-NH1 2.78Å; E240-R418 IonicContact OE2-NH2 2.98Å; E240-R418 PolarHBondContact OE2-NH2 2.97Å; E240-R418 VanDerWaalsContact OE2-NH2 3.14Å
241G77.6Confident92.4Very high76 Ų7636.8 Ų36.878%0.78421%0.212SC*.THydrogen-bonded Turntrans70.1-145.8-179.100000113.5
242V68.4Low92.4Very high123 Ų12337.3 Ų37.375%0.74522%0.215SC*.THydrogen-bonded Turntrans-107.40.2-175-64.20000113.5
243L79.4Confident92.4Very high48 Ų4837.1 Ų37.125%0.25121%0.214SC..SBendtrans-78.1157.9-177.7-61.1-176.1000111.4Y237 Y276Y237-L243 HydrophobicContact CD2-CD1 3.7Å; Y237-L243 HydrophobicContact CG-CD1 4.29Å; L243-Y276 HydrophobicContact CD2-CE2 3.84Å
244M90.3Very high92.4Very high11 Ų1138.1 Ų38.15%0.05422%0.218CC..PPolyproline II helixtrans-66.2142.1175.1-63.7-167.377.700111.3S234 E248 Y272 M275S234-M244 VanDerWaalsContact CA-O 3.3Å; S234-M244 WeakPolarHBondContact CA-O 3.31Å; S234-M244 WeakPolarHBondContact CB-O 3.09Å; S234-M244 PolarHBondContact OG-O 2.69Å; M244-E248 HydrophobicContact CE-CB 3.91Å; M244-Y272 HydrophobicContact CB-CE2 4.09Å; M244-Y272 VanDerWaalsContact CB-OH 3.29Å; M244-Y272 WeakPolarHBondContact CB-OH 3.42Å; M244-Y272 HydrophobicContact CE-CD2 4.03Å; M244-Y272 HydrophobicContact CE-CE2 3.57Å; M244-Y272 HydrophobicContact CG-CE2 4.42Å; M244-Y272 HydrophobicContact SD-CD2 4Å; M244-Y272 HydrophobicContact SD-CE2 3.43Å; M244-Y272 WeakPolarHBondContact SD-CE2 3.31Å; M244-M275 HydrophobicContact CE-CB 4.06Å; M244-M275 HydrophobicContact CE-CE 3.61Å; M244-M275 HydrophobicContact CE-SD 4.5Å; M244-M275 HydrophobicContact SD-CB 3.86Å
245S94.6Very high92.1Very high13 Ų1341.9 Ų41.99%0.09124%0.236CC..PPolyproline II helixtrans-82.5164.1178.763.60000113.6N238 K247 E248 L249N238-S245 WeakPolarHBondContact OD1-CB 3.28Å; S245-K247 PolarHBondContact O-N 3Å; S245-E248 WeakPolarHBondContact CB-OE2 3.17Å; S245-E248 PolarHBondContact N-OE2 3.22Å; S245-E248 PolarHBondContact O-N 3.15Å; S245-E248 WeakPolarHBondContact OG-CG 3.48Å; S245-E248 PolarHBondContact OG-N 3.29Å; S245-E248 PolarHBondContact OG-OE2 3.47Å; S245-L249 PolarHBondContact O-N 2.96Å
246I96.9Very high91.4Very high0 Ų047.9 Ų47.90%027%0.273CS..Hα-helixtrans-56.3-42.1171.3-64.6171.5000110.6V175 V235 N238 E248 L249 C250V175-I246 HydrophobicContact CB-CD1 4.22Å; V175-I246 HydrophobicContact CG2-CB 4.41Å; V175-I246 HydrophobicContact CG2-CD1 3.68Å; V175-I246 HydrophobicContact CG2-CG2 4.1Å; V235-I246 HydrophobicContact CB-CD1 4.29Å; V235-I246 HydrophobicContact CB-CG1 4.42Å; V235-I246 HydrophobicContact CG1-CD1 4.11Å; V235-I246 HydrophobicContact CG2-CD1 4.01Å; V235-I246 HydrophobicContact CG2-CG1 3.86Å; N238-I246 HydrophobicContact CB-CD1 3.78Å; N238-I246 HydrophobicContact CB-CG1 3.92Å; N238-I246 WeakPolarHBondContact OD1-CB 3.35Å; N238-I246 WeakPolarHBondContact OD1-CG1 3.49Å; N238-I246 PolarHBondContact OD1-N 3.37Å; I246-E248 VanDerWaalsContact C-N 3.33Å; I246-E248 PolarHBondContact O-N 3.31Å; I246-L249 PolarHBondContact O-N 3.35Å; I246-C250 VanDerWaalsContact O-CB 3.29Å; I246-C250 WeakPolarHBondContact O-CB 3.41Å; I246-C250 PolarHBondContact O-N 2.85Å; I246-C250 PolarHBondContact O-SG 3.36Å
247K96.5Very high90.5Very high139 Ų13948.9 Ų48.960%0.60428%0.28SS*.Hα-helixtrans-60.4-42.2178.1-176.1178.8177.6-1780112.1V175 S245 G251V175-K247 PolarHBondContact O-N 2.99Å; S245-K247 PolarHBondContact O-N 3Å; K247-G251 PolarHBondContact O-N 3.24Å
248E96.1Very high89.6Confident98 Ų9856 Ų5646%0.45831%0.306SS..Hα-helixtrans-70-45.3178.2-70163.2127.100111.6M244 S245 I246 C250 G251 V252M244-E248 HydrophobicContact CE-CB 3.91Å; S245-E248 WeakPolarHBondContact CB-OE2 3.17Å; S245-E248 PolarHBondContact N-OE2 3.22Å; S245-E248 PolarHBondContact O-N 3.15Å; S245-E248 WeakPolarHBondContact OG-CG 3.48Å; S245-E248 PolarHBondContact OG-N 3.29Å; S245-E248 PolarHBondContact OG-OE2 3.47Å; I246-E248 VanDerWaalsContact C-N 3.33Å; I246-E248 PolarHBondContact O-N 3.31Å; E248-C250 PolarHBondContact O-N 3.39Å; E248-G251 PolarHBondContact O-N 3.19Å; E248-V252 WeakPolarHBondContact O-CG2 3.31Å; E248-V252 PolarHBondContact O-N 2.96Å
249L97.1Very high88.7Confident0 Ų059.4 Ų59.40%033%0.325CS..Hα-helixtrans-53.8-55.1173171.258.7000111.3L170 I231 S245 I246 G251 V252 M253 Y272L170-L249 HydrophobicContact CD2-CD2 3.42Å; L170-L249 VanDerWaalsContact CD2-CD2 3.42Å; L170-L249 HydrophobicContact CD2-CG 4.38Å; I231-L249 HydrophobicContact CB-CD2 4.48Å; I231-L249 HydrophobicContact CG1-CD1 4.47Å; I231-L249 HydrophobicContact CG1-CD2 4.3Å; I231-L249 HydrophobicContact CG2-CD2 3.86Å; S245-L249 PolarHBondContact O-N 2.96Å; I246-L249 PolarHBondContact O-N 3.35Å; L249-G251 VanDerWaalsContact C-N 3.29Å; L249-G251 PolarHBondContact O-N 2.96Å; L249-V252 PolarHBondContact O-N 2.89Å; L249-V252 VanDerWaalsContact O-N 3.16Å; L249-M253 HydrophobicContact CD1-CG 3.76Å; L249-M253 HydrophobicContact CG-CG 4.44Å; L249-M253 WeakPolarHBondContact O-CG 3.47Å; L249-M253 PolarHBondContact O-N 3.19Å; L249-Y272 HydrophobicContact CB-CD2 4.35Å; L249-Y272 HydrophobicContact CB-CE1 4.41Å; L249-Y272 HydrophobicContact CB-CE2 3.63Å; L249-Y272 HydrophobicContact CD1-CD1 3.61Å; L249-Y272 HydrophobicContact CD1-CD2 3.9Å; L249-Y272 HydrophobicContact CD1-CE1 3.54Å; L249-Y272 HydrophobicContact CD1-CE2 3.85Å; L249-Y272 HydrophobicContact CD1-CG 3.76Å; L249-Y272 HydrophobicContact CG-CE1 4.39Å; L249-Y272 HydrophobicContact CG-CE2 4.32Å
250C98Very high87.7Confident3 Ų361.2 Ų61.22%0.0234%0.34CS..Hα-helixtrans-67.9-30.9-177.8-70.90000112.4G176 C181 I246 E248 M253 T254G176-C250 WeakPolarHBondContact O-CB 3.39Å; C181-C250 HydrophobicContact CB-CB 3.64Å; C181-C250 WeakPolarHBondContact CB-SG 3.32Å; C181-C250 WeakPolarHBondContact SG-CA 3.46Å; C181-C250 WeakPolarHBondContact SG-CB 3.47Å; C181-C250 CovalentContact SG-SG 2.04Å; C181-C250 PolarHBondContact SG-SG 3.39Å; I246-C250 VanDerWaalsContact O-CB 3.29Å; I246-C250 WeakPolarHBondContact O-CB 3.41Å; I246-C250 PolarHBondContact O-N 2.85Å; I246-C250 PolarHBondContact O-SG 3.36Å; E248-C250 PolarHBondContact O-N 3.39Å; C250-M253 PolarHBondContact O-N 2.79Å; C250-T254 VanDerWaalsContact O-CB 3.3Å; C250-T254 WeakPolarHBondContact O-CB 3.45Å; C250-T254 WeakPolarHBondContact O-CG2 3.48Å; C250-T254 PolarHBondContact O-N 3.33Å; C250-T254 PolarHBondContact O-OG1 3.08Å
251G97Very high87Confident41 Ų4166.6 Ų66.642%0.42336%0.364SS..Hα-helixtrans-58.1-46.617000000112.4K247 E248 L249 E255K247-G251 PolarHBondContact O-N 3.24Å; E248-G251 PolarHBondContact O-N 3.19Å; L249-G251 VanDerWaalsContact C-N 3.29Å; L249-G251 PolarHBondContact O-N 2.96Å; G251-E255 PolarHBondContact O-N 3.43Å; G251-E255 VanDerWaalsContact O-N 3.15Å
252V96.3Very high86.6Confident11 Ų1169 Ų697%0.06735%0.349CS..Hα-helixtrans-67.8-47.8176.71770000111.2E248 L249 T254 E255 R268 K271 Y272 M275E248-V252 WeakPolarHBondContact O-CG2 3.31Å; E248-V252 PolarHBondContact O-N 2.96Å; L249-V252 PolarHBondContact O-N 2.89Å; L249-V252 VanDerWaalsContact O-N 3.16Å; V252-T254 VanDerWaalsContact C-N 3.26Å; V252-T254 PolarHBondContact O-N 2.79Å; V252-E255 PolarHBondContact O-N 2.55Å; V252-R268 WeakPolarHBondContact CG1-O 3.46Å; V252-K271 HydrophobicContact CG1-CB 4.47Å; V252-K271 HydrophobicContact CG1-CD 4.18Å; V252-K271 HydrophobicContact CG1-CG 4.31Å; V252-Y272 HydrophobicContact CB-CD2 4.35Å; V252-Y272 HydrophobicContact CG2-CD2 4.27Å; V252-M275 HydrophobicContact CG2-CE 4.32Å; V252-M275 HydrophobicContact CG2-SD 3.81Å
253M97.2Very high86.8Confident0 Ų067.9 Ų67.90%034%0.335CS..Hα-helixtrans-67.2-26.1-175.8-66.9-52.8-72.100113.1K184 V185 A188 L249 C250 R268 Y269K184-M253 HydrophobicContact CB-CB 4.28Å; K184-M253 HydrophobicContact CB-CE 4.14Å; K184-M253 VanDerWaalsContact O-CE 3.32Å; K184-M253 WeakPolarHBondContact O-CE 3.21Å; V185-M253 HydrophobicContact CG2-CE 4.19Å; V185-M253 HydrophobicContact CG2-CG 4.15Å; A188-M253 HydrophobicContact CB-CE 3.99Å; L249-M253 HydrophobicContact CD1-CG 3.76Å; L249-M253 HydrophobicContact CG-CG 4.44Å; L249-M253 WeakPolarHBondContact O-CG 3.47Å; L249-M253 PolarHBondContact O-N 3.19Å; C250-M253 PolarHBondContact O-N 2.79Å; M253-R268 HydrophobicContact CE-CB 4.42Å; M253-R268 VanDerWaalsContact O-CD 3.27Å; M253-R268 WeakPolarHBondContact O-CD 3.46Å; M253-R268 PolarHBondContact O-NH1 3.29Å; M253-R268 HydrophobicContact SD-CB 3.84Å; M253-Y269 HydrophobicContact SD-CD2 4.46Å
254T95.4Very high87.3Confident32 Ų3267.8 Ų67.820%0.19634%0.337CS..Hα-helixtrans-106.1-1.5-177.668.40000115.1K180 C181 C250 V252 T256K180-T254 HydrophobicContact CB-CG2 4.31Å; K180-T254 HydrophobicContact CD-CG2 4.21Å; K180-T254 HydrophobicContact CG-CG2 4.1Å; K180-T254 PolarHBondContact NZ-O 3.39Å; C181-T254 HydrophobicContact CB-CG2 3.94Å; C250-T254 VanDerWaalsContact O-CB 3.3Å; C250-T254 WeakPolarHBondContact O-CB 3.45Å; C250-T254 WeakPolarHBondContact O-CG2 3.48Å; C250-T254 PolarHBondContact O-N 3.33Å; C250-T254 PolarHBondContact O-OG1 3.08Å; V252-T254 VanDerWaalsContact C-N 3.26Å; V252-T254 PolarHBondContact O-N 2.79Å; T254-T256 PolarHBondContact O-N 2.92Å
255E90.4Very high87.5Confident78 Ų7867.3 Ų67.336%0.36434%0.335SS..  trans-42.2129.4-177.4-171.5177.6179.300112.3G251 V252 R268 K271G251-E255 PolarHBondContact O-N 3.43Å; G251-E255 VanDerWaalsContact O-N 3.15Å; V252-E255 PolarHBondContact O-N 2.55Å; E255-R268 VanDerWaalsContact O-CZ 3.25Å; E255-R268 PolarHBondContact O-NH1 3.09Å; E255-R268 PolarHBondContact O-NH2 3.38Å; E255-K271 IonicContact OE1-NZ 3.59Å; E255-K271 IonicContact OE2-NZ 3.73Å; E255-K271 PolarHBondContact OE2-NZ 3.41Å
256T82.4Confident87.6Confident126 Ų12667.6 Ų67.677%0.77333%0.334SS*.  trans-90.8126.3177.650.50000110.1T254T254-T256 PolarHBondContact O-N 2.92Å
257T77.9Confident87.5Confident38 Ų3870.6 Ų70.623%0.23335%0.346CS..  trans-147.2149.4-178-178.80000111N259 R262 K263T257-N259 PolarHBondContact OG1-N 3.25Å; T257-R262 HydrophobicContact CG2-CB 3.67Å; T257-K263 HydrophobicContact CG2-CG 3.98Å; T257-K263 WeakPolarHBondContact O-CE 3.49Å
258R74.7Confident87.4Confident246 Ų24664.6 Ų64.693%0.92832%0.32SS*.SBendtrans-79-20.2174.9-68.3-174.6179.4179.50.1112.6T260R258-T260 PolarHBondContact O-N 2.91Å
259N75.5Confident87.5Confident76 Ų7660 Ų6041%0.40630%0.298SS..  trans-76.8116.1179.4-178.3-36.6000110.4T257 F261 R262 K263T257-N259 PolarHBondContact OG1-N 3.25Å; N259-F261 PolarHBondContact O-N 3.27Å; N259-F261 WeakPolarHBondContact OD1-CB 3.29Å; N259-F261 PolarHBondContact OD1-N 3.25Å; N259-R262 HydrophobicContact CB-CB 4.19Å; N259-R262 HydrophobicContact CB-CG 4.21Å; N259-R262 PolarHBondContact O-N 3.21Å; N259-R262 PolarHBondContact OD1-N 2.91Å; N259-K263 WeakPolarHBondContact O-CG 3.33Å; N259-K263 PolarHBondContact O-N 3.08Å
260T72.6Confident87.5Confident111 Ų11161 Ų6168%0.68130%0.304SS*.SBendtrans-62.1-36.9-177.244.70000113.4R258 R262 K263R258-T260 PolarHBondContact O-N 2.91Å; T260-R262 PolarHBondContact O-N 3.46Å; T260-K263 WeakPolarHBondContact O-CB 3.25Å; T260-K263 PolarHBondContact O-N 3.1Å
261F72.4Confident87.3Confident129 Ų12964.2 Ų64.257%0.56632%0.317SS*.G310 helixtrans-62.4-43.5175.4179.2-103.1000111.4N259 K263 C264 Y267N259-F261 PolarHBondContact O-N 3.27Å; N259-F261 WeakPolarHBondContact OD1-CB 3.29Å; N259-F261 PolarHBondContact OD1-N 3.25Å; F261-K263 PolarHBondContact O-N 3.47Å; F261-C264 VanDerWaalsContact O-CB 3.26Å; F261-C264 WeakPolarHBondContact O-CB 3.36Å; F261-C264 PolarHBondContact O-N 2.72Å; F261-C264 VanDerWaalsContact O-N 3.14Å; F261-Y267 HydrophobicContact CD1-CD2 4.02Å; F261-Y267 HydrophobicContact CD1-CE2 4.21Å; F261-Y267 HydrophobicContact CD1-CG 4.33Å; F261-Y267 AromaticContact CE1-CD2 3.23Å; F261-Y267 HydrophobicContact CE1-CD2 3.23Å; F261-Y267 AromaticContact CE1-CE2 3.44Å; F261-Y267 HydrophobicContact CE1-CE2 3.44Å; F261-Y267 VanDerWaalsContact CE1-CE2 3.44Å; F261-Y267 AromaticContact CE1-CG 3.93Å; F261-Y267 HydrophobicContact CE1-CG 3.93Å; F261-Y267 AromaticContact CZ-CD2 3.69Å; F261-Y267 HydrophobicContact CZ-CD2 3.69Å; F261-Y267 HydrophobicContact CZ-CE2 4.23Å; F261-Y267 HydrophobicContact CZ-CG 4.41Å
262R70.6Confident87.2Confident126 Ų12662.3 Ų62.348%0.47530%0.297SS..G310 helixtrans-71.7-7175.2-62.6-172.5175.3-177.60113.8T257 N259 T260 Y267 R268T257-R262 HydrophobicContact CG2-CB 3.67Å; N259-R262 HydrophobicContact CB-CB 4.19Å; N259-R262 HydrophobicContact CB-CG 4.21Å; N259-R262 PolarHBondContact O-N 3.21Å; N259-R262 PolarHBondContact OD1-N 2.91Å; T260-R262 PolarHBondContact O-N 3.46Å; R262-Y267 HydrophobicContact CB-CD1 4.34Å; R262-Y267 HydrophobicContact CB-CE1 4.24Å; R262-Y267 HydrophobicContact CG-CD1 4.25Å; R262-Y267 HydrophobicContact CG-CE1 3.76Å; R262-R268 PolarHBondContact O-NE 2.9Å; R262-R268 PolarHBondContact O-NH2 3Å
263K71.9Confident87.2Confident100 Ų10061.8 Ų61.844%0.43529%0.294SS..G310 helixtrans-81.5-20.5170.3-67.5179.7-176.3178.30113.3T257 N259 T260 F261 A265 R268T257-K263 HydrophobicContact CG2-CG 3.98Å; T257-K263 WeakPolarHBondContact O-CE 3.49Å; N259-K263 WeakPolarHBondContact O-CG 3.33Å; N259-K263 PolarHBondContact O-N 3.08Å; T260-K263 WeakPolarHBondContact O-CB 3.25Å; T260-K263 PolarHBondContact O-N 3.1Å; F261-K263 PolarHBondContact O-N 3.47Å; K263-A265 PolarHBondContact O-N 3.45Å; K263-R268 PolarHBondContact O-NE 3.4Å
264C88.9Confident86.9Confident46 Ų4665 Ų6531%0.31131%0.309SS..  trans-64.6129.9-178.1-173.90000111F261 Y266 Y267 R268F261-C264 VanDerWaalsContact O-CB 3.26Å; F261-C264 WeakPolarHBondContact O-CB 3.36Å; F261-C264 PolarHBondContact O-N 2.72Å; F261-C264 VanDerWaalsContact O-N 3.14Å; C264-Y266 VanDerWaalsContact C-N 3.3Å; C264-Y266 PolarHBondContact O-N 3.23Å; C264-Y267 PolarHBondContact O-N 2.72Å; C264-R268 WeakPolarHBondContact O-CG 3.47Å; C264-R268 PolarHBondContact O-N 2.84Å
265A95.4Very high86.8Confident0 Ų067 Ų670%032%0.317CS..Hα-helixtrans-61.1-38.5-179.500000112.4K184 E187 A188 L191 K263 Y267 R268 Y269K184-A265 HydrophobicContact CD-CB 4.12Å; K184-A265 WeakPolarHBondContact O-CB 3.36Å; E187-A265 HydrophobicContact CB-CB 3.76Å; E187-A265 HydrophobicContact CG-CB 3.67Å; A188-A265 HydrophobicContact CB-CB 4.05Å; L191-A265 HydrophobicContact CD1-CB 4.22Å; K263-A265 PolarHBondContact O-N 3.45Å; A265-Y267 PolarHBondContact O-N 3.03Å; A265-R268 PolarHBondContact O-N 3.48Å; A265-Y269 WeakPolarHBondContact O-CB 3.02Å; A265-Y269 PolarHBondContact O-N 2.9Å
266Y96.4Very high86.8Confident20 Ų2065.5 Ų65.58%0.07831%0.308CS..Hα-helixtrans-53.3-50.7173.4-179.8-81.3000112.2L191 V192 D207 F208 C264 R268 Y269 N270L191-Y266 HydrophobicContact CB-CD2 4.24Å; V192-Y266 HydrophobicContact CB-CE2 4.44Å; V192-Y266 HydrophobicContact CG2-CD2 3.67Å; V192-Y266 HydrophobicContact CG2-CE2 3.77Å; D207-Y266 HydrophobicContact CB-CE1 4.18Å; D207-Y266 WeakPolarHBondContact CB-OH 3.48Å; D207-Y266 WeakPolarHBondContact OD2-CE1 3.31Å; D207-Y266 PolarHBondContact OD2-OH 2.88Å; F208-Y266 HydrophobicContact CE2-CD2 4.45Å; F208-Y266 HydrophobicContact CE2-CE1 4.37Å; F208-Y266 AromaticContact CE2-CE2 3.75Å; F208-Y266 HydrophobicContact CE2-CE2 3.75Å; F208-Y266 AromaticContact CE2-CZ 3.7Å; F208-Y266 HydrophobicContact CZ-CE2 4.3Å; C264-Y266 VanDerWaalsContact C-N 3.3Å; C264-Y266 PolarHBondContact O-N 3.23Å; Y266-R268 VanDerWaalsContact C-N 3.35Å; Y266-R268 PolarHBondContact O-N 3.32Å; Y266-Y269 PolarHBondContact O-N 3.11Å; Y266-N270 WeakPolarHBondContact O-CB 3.46Å; Y266-N270 PolarHBondContact O-N 3.01Å
267Y94.6Very high87Confident63 Ų6360.4 Ų60.425%0.24728%0.276CS..Hα-helixtrans-66-38.1-178.6175.4-91.4000112.1F261 R262 C264 A265 Y269 K271F261-Y267 HydrophobicContact CD1-CD2 4.02Å; F261-Y267 HydrophobicContact CD1-CE2 4.21Å; F261-Y267 HydrophobicContact CD1-CG 4.33Å; F261-Y267 AromaticContact CE1-CD2 3.23Å; F261-Y267 HydrophobicContact CE1-CD2 3.23Å; F261-Y267 AromaticContact CE1-CE2 3.44Å; F261-Y267 HydrophobicContact CE1-CE2 3.44Å; F261-Y267 VanDerWaalsContact CE1-CE2 3.44Å; F261-Y267 AromaticContact CE1-CG 3.93Å; F261-Y267 HydrophobicContact CE1-CG 3.93Å; F261-Y267 AromaticContact CZ-CD2 3.69Å; F261-Y267 HydrophobicContact CZ-CD2 3.69Å; F261-Y267 HydrophobicContact CZ-CE2 4.23Å; F261-Y267 HydrophobicContact CZ-CG 4.41Å; R262-Y267 HydrophobicContact CB-CD1 4.34Å; R262-Y267 HydrophobicContact CB-CE1 4.24Å; R262-Y267 HydrophobicContact CG-CD1 4.25Å; R262-Y267 HydrophobicContact CG-CE1 3.76Å; C264-Y267 PolarHBondContact O-N 2.72Å; A265-Y267 PolarHBondContact O-N 3.03Å; Y267-Y269 VanDerWaalsContact C-N 3.33Å; Y267-K271 PolarHBondContact O-N 2.71Å
268R95.5Very high87.4Confident13 Ų1365 Ų655%0.04930%0.299CS..Hα-helixtrans-65.1-41.3177.9-67.7173.7-175.7-158.3-11.1111.4V252 M253 E255 R262 K263 C264 A265 Y266 K271 Y272V252-R268 WeakPolarHBondContact CG1-O 3.46Å; M253-R268 HydrophobicContact CE-CB 4.42Å; M253-R268 VanDerWaalsContact O-CD 3.27Å; M253-R268 WeakPolarHBondContact O-CD 3.46Å; M253-R268 PolarHBondContact O-NH1 3.29Å; M253-R268 HydrophobicContact SD-CB 3.84Å; E255-R268 VanDerWaalsContact O-CZ 3.25Å; E255-R268 PolarHBondContact O-NH1 3.09Å; E255-R268 PolarHBondContact O-NH2 3.38Å; R262-R268 PolarHBondContact O-NE 2.9Å; R262-R268 PolarHBondContact O-NH2 3Å; K263-R268 PolarHBondContact O-NE 3.4Å; C264-R268 WeakPolarHBondContact O-CG 3.47Å; C264-R268 PolarHBondContact O-N 2.84Å; A265-R268 PolarHBondContact O-N 3.48Å; Y266-R268 VanDerWaalsContact C-N 3.35Å; Y266-R268 PolarHBondContact O-N 3.32Å; R268-K271 WeakPolarHBondContact O-CB 3.3Å; R268-K271 PolarHBondContact O-N 3.31Å; R268-Y272 PolarHBondContact O-N 3.5Å
269Y97.3Very high87.8Confident0 Ų056.9 Ų56.90%028%0.277CS..Hα-helixtrans-70.2-41.6178.9-175.7-131000112A188 F189 F208 L227 I231 M253 A265 Y266 Y267 K271 Y272 V273A188-Y269 HydrophobicContact CB-CD1 4.16Å; A188-Y269 HydrophobicContact CB-CG 4.12Å; F189-Y269 HydrophobicContact CE2-CD1 4.46Å; F189-Y269 AromaticContact CE2-CE1 3.85Å; F189-Y269 HydrophobicContact CE2-CE1 3.85Å; F189-Y269 AromaticContact CE2-CZ 3.97Å; F189-Y269 HydrophobicContact CZ-CE1 4.05Å; F208-Y269 AromaticContact CE1-CD1 3.69Å; F208-Y269 HydrophobicContact CE1-CD1 3.69Å; F208-Y269 AromaticContact CE1-CE1 3.92Å; F208-Y269 HydrophobicContact CE1-CE1 3.92Å; F208-Y269 HydrophobicContact CE1-CG 4.4Å; F208-Y269 AromaticContact CZ-CD1 4Å; F208-Y269 HydrophobicContact CZ-CD1 4Å; F208-Y269 HydrophobicContact CZ-CE1 4.45Å; L227-Y269 WeakPolarHBondContact CA-OH 3.34Å; L227-Y269 HydrophobicContact CB-CE1 4.04Å; L227-Y269 VanDerWaalsContact CB-OH 3.24Å; L227-Y269 WeakPolarHBondContact CB-OH 3.29Å; L227-Y269 HydrophobicContact CD1-CE1 4.23Å; L227-Y269 HydrophobicContact CD2-CE1 3.92Å; L227-Y269 HydrophobicContact CG-CE1 4.27Å; L227-Y269 PolarHBondContact O-OH 2.94Å; I231-Y269 HydrophobicContact CD1-CD2 4.19Å; I231-Y269 HydrophobicContact CD1-CE2 3.61Å; I231-Y269 HydrophobicContact CG1-CE2 3.77Å; M253-Y269 HydrophobicContact SD-CD2 4.46Å; A265-Y269 WeakPolarHBondContact O-CB 3.02Å; A265-Y269 PolarHBondContact O-N 2.9Å; Y266-Y269 PolarHBondContact O-N 3.11Å; Y267-Y269 VanDerWaalsContact C-N 3.33Å; Y269-K271 VanDerWaalsContact C-N 3.34Å; Y269-K271 PolarHBondContact O-N 3.14Å; Y269-Y272 HydrophobicContact CD2-CD1 4.36Å; Y269-Y272 HydrophobicContact CE2-CD1 4.22Å; Y269-Y272 WeakPolarHBondContact O-CA 3.43Å; Y269-Y272 WeakPolarHBondContact O-CB 3.32Å; Y269-Y272 PolarHBondContact O-N 3.33Å; Y269-V273 HydrophobicContact CD2-CG2 4.18Å; Y269-V273 HydrophobicContact CE1-CG2 4.16Å; Y269-V273 HydrophobicContact CE2-CG2 3.68Å; Y269-V273 WeakPolarHBondContact O-CG2 3.3Å; Y269-V273 PolarHBondContact O-N 2.91Å
270N96.1Very high87.9Confident23 Ų2355 Ų5512%0.12327%0.27CS..Hα-helixtrans-50.9-52.6167.5170.1-36000111.3D207 F208 Y266 Y272 V273 Q274D207-N270 VanDerWaalsContact C-ND2 3.27Å; D207-N270 WeakPolarHBondContact CA-ND2 3.3Å; D207-N270 VanDerWaalsContact CB-ND2 3.29Å; D207-N270 WeakPolarHBondContact CB-ND2 3.33Å; D207-N270 PolarHBondContact O-ND2 3.07Å; D207-N270 PolarHBondContact O-OD1 2.78Å; F208-N270 HydrophobicContact CE1-CB 4.11Å; F208-N270 HydrophobicContact CZ-CB 4.29Å; Y266-N270 WeakPolarHBondContact O-CB 3.46Å; Y266-N270 PolarHBondContact O-N 3.01Å; N270-Y272 PolarHBondContact O-N 3.13Å; N270-V273 PolarHBondContact O-N 3.12Å; N270-V273 VanDerWaalsContact O-N 3.11Å; N270-Q274 WeakPolarHBondContact O-CG 3.34Å; N270-Q274 PolarHBondContact O-N 3.29Å
271K94.8Very high88.2Confident70 Ų7057.9 Ų57.930%0.30428%0.281SS..Hα-helixtrans-54.7-42.2177.5175.3-177.1169.1-173.20111.6V252 E255 Y267 R268 Y269 Q274 M275V252-K271 HydrophobicContact CG1-CB 4.47Å; V252-K271 HydrophobicContact CG1-CD 4.18Å; V252-K271 HydrophobicContact CG1-CG 4.31Å; E255-K271 IonicContact OE1-NZ 3.59Å; E255-K271 IonicContact OE2-NZ 3.73Å; E255-K271 PolarHBondContact OE2-NZ 3.41Å; Y267-K271 PolarHBondContact O-N 2.71Å; R268-K271 WeakPolarHBondContact O-CB 3.3Å; R268-K271 PolarHBondContact O-N 3.31Å; Y269-K271 VanDerWaalsContact C-N 3.34Å; Y269-K271 PolarHBondContact O-N 3.14Å; K271-Q274 PolarHBondContact O-N 3.29Å; K271-M275 HydrophobicContact CG-SD 4.34Å; K271-M275 VanDerWaalsContact O-CG 3.32Å; K271-M275 WeakPolarHBondContact O-CG 3.41Å; K271-M275 PolarHBondContact O-N 2.94Å
272Y95.5Very high88.6Confident0 Ų056.3 Ų56.30%028%0.275CS..Hα-helixtrans-64.9-45.9177.3-177-101.9000112.4I230 S234 M244 L249 V252 R268 Y269 N270 Q274 M275 Y276I230-Y272 HydrophobicContact CG2-CD1 4.17Å; I230-Y272 HydrophobicContact CG2-CE1 3.76Å; S234-Y272 WeakPolarHBondContact CB-OH 3.32Å; S234-Y272 PolarHBondContact OG-OH 3.13Å; M244-Y272 HydrophobicContact CB-CE2 4.09Å; M244-Y272 VanDerWaalsContact CB-OH 3.29Å; M244-Y272 WeakPolarHBondContact CB-OH 3.42Å; M244-Y272 HydrophobicContact CE-CD2 4.03Å; M244-Y272 HydrophobicContact CE-CE2 3.57Å; M244-Y272 HydrophobicContact CG-CE2 4.42Å; M244-Y272 HydrophobicContact SD-CD2 4Å; M244-Y272 HydrophobicContact SD-CE2 3.43Å; M244-Y272 WeakPolarHBondContact SD-CE2 3.31Å; L249-Y272 HydrophobicContact CB-CD2 4.35Å; L249-Y272 HydrophobicContact CB-CE1 4.41Å; L249-Y272 HydrophobicContact CB-CE2 3.63Å; L249-Y272 HydrophobicContact CD1-CD1 3.61Å; L249-Y272 HydrophobicContact CD1-CD2 3.9Å; L249-Y272 HydrophobicContact CD1-CE1 3.54Å; L249-Y272 HydrophobicContact CD1-CE2 3.85Å; L249-Y272 HydrophobicContact CD1-CG 3.76Å; L249-Y272 HydrophobicContact CG-CE1 4.39Å; L249-Y272 HydrophobicContact CG-CE2 4.32Å; V252-Y272 HydrophobicContact CB-CD2 4.35Å; V252-Y272 HydrophobicContact CG2-CD2 4.27Å; R268-Y272 PolarHBondContact O-N 3.5Å; Y269-Y272 HydrophobicContact CD2-CD1 4.36Å; Y269-Y272 HydrophobicContact CE2-CD1 4.22Å; Y269-Y272 WeakPolarHBondContact O-CA 3.43Å; Y269-Y272 WeakPolarHBondContact O-CB 3.32Å; Y269-Y272 PolarHBondContact O-N 3.33Å; N270-Y272 PolarHBondContact O-N 3.13Å; Y272-Q274 VanDerWaalsContact C-N 3.29Å; Y272-Q274 PolarHBondContact O-N 2.92Å; Y272-M275 WeakPolarHBondContact O-CB 3.35Å; Y272-M275 PolarHBondContact O-N 2.86Å; Y272-M275 VanDerWaalsContact O-N 3.07Å; Y272-Y276 PolarHBondContact O-N 3.21Å
273V94.9Very high89.3Confident0 Ų056.2 Ų56.20%029%0.294CS..Hα-helixtrans-59.2-40.7176.1170.10000111.2F208 L227 I230 Y269 N270 M275 Y276 H277F208-V273 HydrophobicContact CD1-CB 4.06Å; F208-V273 HydrophobicContact CD1-CG1 4.07Å; F208-V273 HydrophobicContact CD1-CG2 3.94Å; F208-V273 HydrophobicContact CE1-CG2 4.09Å; L227-V273 HydrophobicContact CD2-CG1 4.49Å; L227-V273 HydrophobicContact CD2-CG2 3.91Å; I230-V273 HydrophobicContact CD1-CB 4.44Å; I230-V273 HydrophobicContact CD1-CG1 3.92Å; I230-V273 HydrophobicContact CD1-CG2 3.99Å; Y269-V273 HydrophobicContact CD2-CG2 4.18Å; Y269-V273 HydrophobicContact CE1-CG2 4.16Å; Y269-V273 HydrophobicContact CE2-CG2 3.68Å; Y269-V273 WeakPolarHBondContact O-CG2 3.3Å; Y269-V273 PolarHBondContact O-N 2.91Å; N270-V273 PolarHBondContact O-N 3.12Å; N270-V273 VanDerWaalsContact O-N 3.11Å; V273-M275 PolarHBondContact O-N 3.11Å; V273-Y276 WeakPolarHBondContact O-CB 3.46Å; V273-Y276 PolarHBondContact O-N 3.15Å; V273-H277 VanDerWaalsContact CG1-CD2 3.48Å; V273-H277 WeakPolarHBondContact CG1-CD2 3.2Å; V273-H277 PolarHBondContact O-CD2 3.21Å; V273-H277 PolarHBondContact O-N 3.17Å
274Q92.2Very high90.3Very high68 Ų6853 Ų5332%0.31828%0.284SS..Hα-helixtrans-64.8-38.7174.1-64.2-63.8-25.100112.6D207 N270 K271 Y272 N278D207-Q274 PolarHBondContact O-NE2 3.25Å; N270-Q274 WeakPolarHBondContact O-CG 3.34Å; N270-Q274 PolarHBondContact O-N 3.29Å; K271-Q274 PolarHBondContact O-N 3.29Å; Y272-Q274 VanDerWaalsContact C-N 3.29Å; Y272-Q274 PolarHBondContact O-N 2.92Å; Q274-N278 VanDerWaalsContact O-CG 3.26Å; Q274-N278 PolarHBondContact O-N 3.21Å; Q274-N278 VanDerWaalsContact O-N 3.13Å; Q274-N278 PolarHBondContact O-ND2 2.98Å
275M91.8Very high90.5Very high74 Ų7451.4 Ų51.437%0.36527%0.272SS..Hα-helixtrans-64.2-43.8173.8-70.6172.56800111.3M244 V252 K271 Y272 V273 N278M244-M275 HydrophobicContact CE-CB 4.06Å; M244-M275 HydrophobicContact CE-CE 3.61Å; M244-M275 HydrophobicContact CE-SD 4.5Å; M244-M275 HydrophobicContact SD-CB 3.86Å; V252-M275 HydrophobicContact CG2-CE 4.32Å; V252-M275 HydrophobicContact CG2-SD 3.81Å; K271-M275 HydrophobicContact CG-SD 4.34Å; K271-M275 VanDerWaalsContact O-CG 3.32Å; K271-M275 WeakPolarHBondContact O-CG 3.41Å; K271-M275 PolarHBondContact O-N 2.94Å; Y272-M275 WeakPolarHBondContact O-CB 3.35Å; Y272-M275 PolarHBondContact O-N 2.86Å; Y272-M275 VanDerWaalsContact O-N 3.07Å; V273-M275 PolarHBondContact O-N 3.11Å; M275-N278 PolarHBondContact O-N 3.47Å
276Y90.7Very high90.3Very high46 Ų4653.1 Ų53.118%0.1828%0.281CS..Hα-helixtrans-60.3-48.6176.1-176.1-85.7000111.2I230 L243 Y272 V273 N278 T279 S280I230-Y276 HydrophobicContact CD1-CD1 4.26Å; I230-Y276 HydrophobicContact CG1-CD1 3.94Å; I230-Y276 HydrophobicContact CG1-CE1 3.94Å; I230-Y276 HydrophobicContact CG1-CG 4.39Å; I230-Y276 HydrophobicContact CG2-CD1 4.18Å; I230-Y276 HydrophobicContact CG2-CD2 3.81Å; I230-Y276 HydrophobicContact CG2-CE2 4.25Å; I230-Y276 HydrophobicContact CG2-CG 3.77Å; L243-Y276 HydrophobicContact CD2-CE2 3.84Å; Y272-Y276 PolarHBondContact O-N 3.21Å; V273-Y276 WeakPolarHBondContact O-CB 3.46Å; V273-Y276 PolarHBondContact O-N 3.15Å; Y276-N278 VanDerWaalsContact C-N 3.28Å; Y276-N278 PolarHBondContact O-N 3.39Å; Y276-T279 WeakPolarHBondContact O-CA 3.22Å; Y276-T279 WeakPolarHBondContact O-CB 3.44Å; Y276-T279 PolarHBondContact O-N 2.9Å; Y276-T279 PolarHBondContact O-OG1 3.17Å; Y276-S280 PolarHBondContact O-N 3.31Å
277H87.6Confident90.3Very high19 Ų1952.2 Ų52.29%0.08828%0.278CS..Hα-helixtrans-58.4-37.3177.4-82.6-59.8000113.3V273 T279 S280V273-H277 VanDerWaalsContact CG1-CD2 3.48Å; V273-H277 WeakPolarHBondContact CG1-CD2 3.2Å; V273-H277 PolarHBondContact O-CD2 3.21Å; V273-H277 PolarHBondContact O-N 3.17Å; H277-T279 PolarHBondContact O-N 3.16Å; H277-T279 VanDerWaalsContact O-N 3.17Å; H277-S280 PolarHBondContact O-N 2.67Å; H277-S280 VanDerWaalsContact O-O 3.05Å; H277-S280 PolarHBondContact O-OG 3.43Å
278N86.3Confident90.3Very high135 Ų13549.7 Ų49.772%0.72227%0.27SS*.THydrogen-bonded Turntrans-66.4-14175.9-71.1-35.4000113.9Q274 M275 Y276Q274-N278 VanDerWaalsContact O-CG 3.26Å; Q274-N278 PolarHBondContact O-N 3.21Å; Q274-N278 VanDerWaalsContact O-N 3.13Å; Q274-N278 PolarHBondContact O-ND2 2.98Å; M275-N278 PolarHBondContact O-N 3.47Å; Y276-N278 VanDerWaalsContact C-N 3.28Å; Y276-N278 PolarHBondContact O-N 3.39Å
279T83.6Confident90.2Very high75 Ų7550.9 Ų50.946%0.4628%0.275SS..THydrogen-bonded Turntrans-93.1-8.6171.667.50000113.1Y276 H277Y276-T279 WeakPolarHBondContact O-CA 3.22Å; Y276-T279 WeakPolarHBondContact O-CB 3.44Å; Y276-T279 PolarHBondContact O-N 2.9Å; Y276-T279 PolarHBondContact O-OG1 3.17Å; H277-T279 PolarHBondContact O-N 3.16Å; H277-T279 VanDerWaalsContact O-N 3.17Å
280S77.6Confident90.1Very high38 Ų3858.2 Ų58.227%0.26631%0.31SS..SBendtrans-102.2154.2178.377.10000111.5Y276 H277 E282Y276-S280 PolarHBondContact O-N 3.31Å; H277-S280 PolarHBondContact O-N 2.67Å; H277-S280 VanDerWaalsContact O-O 3.05Å; H277-S280 PolarHBondContact O-OG 3.43Å; S280-E282 PolarHBondContact O-N 2.91Å; S280-E282 PolarHBondContact OG-N 2.91Å
281D78Confident89.9Confident171 Ų17159.9 Ų59.991%0.91432%0.317SS*.SBendtrans-81.33170.8-71.4-32.2000112.7
282E81.1Confident89.8Confident96 Ų9658.1 Ų58.145%0.44931%0.312SS..  trans-83132.1-178.9-63.2-159.8150.400111.5S280 C284 R305S280-E282 PolarHBondContact O-N 2.91Å; S280-E282 PolarHBondContact OG-N 2.91Å; E282-C284 VanDerWaalsContact C-N 3.35Å; E282-C284 PolarHBondContact O-N 2.82Å; E282-R305 IonicContact OE1-NH2 3.33Å; E282-R305 PolarHBondContact OE1-NH2 3.41Å
283S85.4Confident89.8Confident123 Ų12358.9 Ų58.986%0.8632%0.317SS*.SBendtrans-76.7-19.9-176.954.70000114.4
284C91.9Very high89.7Confident34 Ų3464.7 Ų64.723%0.2334%0.342CS..SBendtrans-166.2163.2-177.352.90000110.5G209 C211 E282 D286G209-C284 CarbonylContact O-C 3.59Å; G209-C284 VanDerWaalsContact O-CA 3.29Å; G209-C284 WeakPolarHBondContact O-CA 3.42Å; G209-C284 VanDerWaalsContact O-CB 3.24Å; G209-C284 WeakPolarHBondContact O-CB 3.44Å; C211-C284 WeakPolarHBondContact CA-SG 3.41Å; C211-C284 HydrophobicContact CB-CB 3.98Å; C211-C284 WeakPolarHBondContact CB-SG 3.38Å; C211-C284 WeakPolarHBondContact SG-CB 3.3Å; C211-C284 PolarHBondContact SG-O 3.25Å; C211-C284 CovalentContact SG-SG 2.03Å; C211-C284 PolarHBondContact SG-SG 3.05Å; E282-C284 VanDerWaalsContact C-N 3.35Å; E282-C284 PolarHBondContact O-N 2.82Å; C284-D286 PolarHBondContact O-N 3.35Å
285L92.9Very high89.7Confident11 Ų1163.3 Ų63.36%0.05834%0.337CS..BIsolated β-bridgetrans-80.8111173.7-168.864.5000110.4G209 C210 C211 L223 N226 L227 V287G209-L285 PolarHBondContact O-N 3.2Å; C210-L285 CarbonylContact C-O 3.51Å; C210-L285 VanDerWaalsContact CA-O 3.25Å; C210-L285 WeakPolarHBondContact CA-O 3.47Å; C211-L285 PolarHBondContact N-O 2.96Å; C211-L285 VanDerWaalsContact SG-C 3.52Å; L223-L285 HydrophobicContact CD1-CD2 3.98Å; N226-L285 HydrophobicContact CB-CD1 3.77Å; N226-L285 HydrophobicContact CB-CD2 4.05Å; N226-L285 HydrophobicContact CB-CG 4.12Å; L227-L285 HydrophobicContact CD2-CD2 4.21Å; L285-V287 HydrophobicContact CD2-CG1 4.12Å; L285-V287 HydrophobicContact CG-CG1 4.01Å; L285-V287 PolarHBondContact O-N 2.87Å
286D92.5Very high89.8Confident37 Ų3760.4 Ų60.420%0.19832%0.322CS..  trans-76.8112.3176.8-171.22.2000110.5N226 C284 S288N226-D286 PolarHBondContact ND2-O 2.87Å; C284-D286 PolarHBondContact O-N 3.35Å; D286-S288 WeakPolarHBondContact OD1-CB 3.48Å; D286-S288 PolarHBondContact OD1-N 2.76Å
287V95.8Very high89.9Confident0 Ų062.8 Ų62.80%034%0.337CS..  trans-112.918-177.3-58.50000111.8C210 Q212 P214 D219 L223 L285C210-V287 HydrophobicContact CB-CG1 4.26Å; C210-V287 HydrophobicContact CB-CG2 4.03Å; Q212-V287 HydrophobicContact CG-CG2 3.86Å; P214-V287 HydrophobicContact CB-CG2 4.23Å; D219-V287 WeakPolarHBondContact CA-O 3.23Å; D219-V287 WeakPolarHBondContact CB-O 3.16Å; L223-V287 HydrophobicContact CB-CB 4.17Å; L223-V287 HydrophobicContact CB-CG1 3.85Å; L223-V287 HydrophobicContact CD1-CG1 3.9Å; L223-V287 HydrophobicContact CG-CG1 4.48Å; L285-V287 HydrophobicContact CD2-CG1 4.12Å; L285-V287 HydrophobicContact CG-CG1 4.01Å; L285-V287 PolarHBondContact O-N 2.87Å
288S95.3Very high90.1Very high11 Ų1165 Ų658%0.07735%0.349CS..  trans-86.7108.7-179.3-172.40000111.5Q212 D286 E290 E291 T292Q212-S288 VanDerWaalsContact CD-CB 3.49Å; Q212-S288 PolarHBondContact NE2-OG 3.05Å; D286-S288 WeakPolarHBondContact OD1-CB 3.48Å; D286-S288 PolarHBondContact OD1-N 2.76Å; S288-E290 PolarHBondContact O-N 3.35Å; S288-E291 PolarHBondContact O-N 2.93Å; S288-E291 VanDerWaalsContact O-N 3.15Å; S288-E291 PolarHBondContact OG-N 3.14Å; S288-E291 VanDerWaalsContact OG-N 3.17Å; S288-T292 PolarHBondContact O-N 2.97Å; S288-T292 PolarHBondContact O-OG1 3.48Å
289H94Very high90.4Very high37 Ų3761 Ų6117%0.17133%0.329CS..Hα-helixtrans-61.4-37174.3-173.867.5000111.4D218 D219 E222 E291 T292 V293D218-H289 HydrophobicContact CB-CB 3.77Å; D219-H289 PolarHBondContact OD1-N 3.26Å; D219-H289 VanDerWaalsContact OD1-N 3.16Å; E222-H289 IonicContact OE2-CG 3.86Å; E222-H289 IonicContact OE2-ND1 3.82Å; E222-H289 PolarHBondContact OE2-ND1 3.38Å; H289-E291 PolarHBondContact O-N 3.24Å; H289-T292 PolarHBondContact O-N 3Å; H289-V293 VanDerWaalsContact O-CG2 3.3Å; H289-V293 WeakPolarHBondContact O-CG2 3.32Å; H289-V293 PolarHBondContact O-N 3.01Å
290E94.1Very high90.5Very high154 Ų15459.6 Ų59.672%0.7232%0.323SS*.Hα-helixtrans-62.8-41.8176.1-174.9177.2-179.300111.9S288 V293 K294S288-E290 PolarHBondContact O-N 3.35Å; E290-V293 PolarHBondContact O-N 2.88Å; E290-K294 VanDerWaalsContact O-CB 3.3Å; E290-K294 WeakPolarHBondContact O-CB 3.48Å; E290-K294 PolarHBondContact O-N 3Å
291E92.8Very high90.3Very high59 Ų5961.3 Ų61.328%0.27633%0.327SS..Hα-helixtrans-71.5-38178-163.760.5-149.500111.2S288 H289 V293 K294 N295S288-E291 PolarHBondContact O-N 2.93Å; S288-E291 VanDerWaalsContact O-N 3.15Å; S288-E291 PolarHBondContact OG-N 3.14Å; S288-E291 VanDerWaalsContact OG-N 3.17Å; H289-E291 PolarHBondContact O-N 3.24Å; E291-V293 PolarHBondContact O-N 3.4Å; E291-K294 PolarHBondContact O-N 3.31Å; E291-K294 IonicContact OE1-NZ 3.68Å; E291-K294 PolarHBondContact OE1-NZ 2.89Å; E291-K294 IonicContact OE2-NZ 2.7Å; E291-K294 PolarHBondContact OE2-NZ 2.95Å; E291-N295 WeakPolarHBondContact O-CB 3.5Å; E291-N295 VanDerWaalsContact O-CG 3.22Å; E291-N295 PolarHBondContact O-N 3.16Å; E291-N295 PolarHBondContact O-ND2 2.59Å; E291-N295 VanDerWaalsContact O-ND2 3.11Å
292T92.5Very high90.1Very high32 Ų3261.1 Ų61.120%0.19632%0.317CS..Hα-helixtrans-55.4-49.8170.6-66.30000110.9E222 S288 H289 K294 N295 L296E222-T292 WeakPolarHBondContact OE1-CB 3.39Å; E222-T292 WeakPolarHBondContact OE1-CG2 3.43Å; E222-T292 PolarHBondContact OE1-OG1 2.95Å; S288-T292 PolarHBondContact O-N 2.97Å; S288-T292 PolarHBondContact O-OG1 3.48Å; H289-T292 PolarHBondContact O-N 3Å; T292-K294 VanDerWaalsContact C-N 3.35Å; T292-K294 PolarHBondContact O-N 3.17Å; T292-N295 PolarHBondContact O-N 3.04Å; T292-L296 HydrophobicContact CG2-CD1 4.1Å; T292-L296 WeakPolarHBondContact O-CG 3.49Å; T292-L296 PolarHBondContact O-N 2.82Å
293V94.8Very high89.7Confident17 Ų1757.7 Ų57.710%0.10330%0.304CS..Hα-helixtrans-61-44.3176.3172.50000111H289 E290 E291 L296 M297 I344 K347 V348H289-V293 VanDerWaalsContact O-CG2 3.3Å; H289-V293 WeakPolarHBondContact O-CG2 3.32Å; H289-V293 PolarHBondContact O-N 3.01Å; E290-V293 PolarHBondContact O-N 2.88Å; E291-V293 PolarHBondContact O-N 3.4Å; V293-L296 PolarHBondContact O-N 3.46Å; V293-M297 HydrophobicContact CG1-CG 4.22Å; V293-M297 WeakPolarHBondContact O-CB 3.45Å; V293-M297 WeakPolarHBondContact O-CG 3.48Å; V293-M297 PolarHBondContact O-N 3.27Å; V293-I344 HydrophobicContact CB-CD1 4.5Å; V293-I344 HydrophobicContact CG2-CD1 3.7Å; V293-K347 HydrophobicContact CG1-CG 3.84Å; V293-K347 HydrophobicContact CG2-CG 4.48Å; V293-V348 HydrophobicContact CG1-CG2 4.46Å
294K93.8Very high88.9Confident121 Ų12163.5 Ų63.553%0.52631%0.307SS..Hα-helixtrans-63.1-41.8179.6175.6165.6153.4-102.50112.4E290 E291 T292 M297 D298E290-K294 VanDerWaalsContact O-CB 3.3Å; E290-K294 WeakPolarHBondContact O-CB 3.48Å; E290-K294 PolarHBondContact O-N 3Å; E291-K294 PolarHBondContact O-N 3.31Å; E291-K294 IonicContact OE1-NZ 3.68Å; E291-K294 PolarHBondContact OE1-NZ 2.89Å; E291-K294 IonicContact OE2-NZ 2.7Å; E291-K294 PolarHBondContact OE2-NZ 2.95Å; T292-K294 VanDerWaalsContact C-N 3.35Å; T292-K294 PolarHBondContact O-N 3.17Å; K294-M297 PolarHBondContact O-N 3.26Å; K294-D298 PolarHBondContact O-N 2.56Å
295N91.6Very high87.8Confident40 Ų4065.5 Ų65.521%0.21431%0.31CS..Hα-helixtrans-62.4-45.6175.1-75.1-36.5000111.1E291 T292 M297 D298 R305E291-N295 WeakPolarHBondContact O-CB 3.5Å; E291-N295 VanDerWaalsContact O-CG 3.22Å; E291-N295 PolarHBondContact O-N 3.16Å; E291-N295 PolarHBondContact O-ND2 2.59Å; E291-N295 VanDerWaalsContact O-ND2 3.11Å; T292-N295 PolarHBondContact O-N 3.04Å; N295-M297 VanDerWaalsContact C-N 3.26Å; N295-M297 PolarHBondContact O-N 2.99Å; N295-D298 WeakPolarHBondContact O-CB 3Å; N295-D298 PolarHBondContact O-N 3.37Å; N295-D298 VanDerWaalsContact O-N 3.13Å; N295-R305 PolarHBondContact ND2-NH1 2.94Å
296L93.9Very high87.2Confident12 Ų1267.9 Ų67.96%0.06332%0.318CS..Hα-helixtrans-69.2-24.3176.8-71.3171000112.8T292 V293 D298 E308 R309 I344 V348T292-L296 HydrophobicContact CG2-CD1 4.1Å; T292-L296 WeakPolarHBondContact O-CG 3.49Å; T292-L296 PolarHBondContact O-N 2.82Å; V293-L296 PolarHBondContact O-N 3.46Å; L296-D298 VanDerWaalsContact C-N 3.31Å; L296-E308 HydrophobicContact CD2-CB 4.12Å; L296-R309 HydrophobicContact CD2-CB 4.31Å; L296-R309 WeakPolarHBondContact O-CD 3.35Å; L296-R309 WeakPolarHBondContact O-CG 3.15Å; L296-R309 PolarHBondContact O-NH1 2.85Å; L296-I344 HydrophobicContact CD1-CD1 3.7Å; L296-I344 HydrophobicContact CD1-CG1 3.56Å; L296-V348 HydrophobicContact CB-CG1 4.1Å; L296-V348 HydrophobicContact CB-CG2 4.02Å; L296-V348 WeakPolarHBondContact O-CG1 3.39Å
297M93.3Very high87.1Confident97 Ų9767.6 Ų67.648%0.47832%0.321SS..Hα-helixtrans-78.5-12173-73.1-70.6-73.900113.3V293 K294 N295 T299 V348V293-M297 HydrophobicContact CG1-CG 4.22Å; V293-M297 WeakPolarHBondContact O-CB 3.45Å; V293-M297 WeakPolarHBondContact O-CG 3.48Å; V293-M297 PolarHBondContact O-N 3.27Å; K294-M297 PolarHBondContact O-N 3.26Å; N295-M297 VanDerWaalsContact C-N 3.26Å; N295-M297 PolarHBondContact O-N 2.99Å; M297-T299 PolarHBondContact O-N 3.48Å; M297-V348 HydrophobicContact CG-CG2 4.38Å; M297-V348 HydrophobicContact SD-CB 4.22Å; M297-V348 HydrophobicContact SD-CG1 4.02Å; M297-V348 HydrophobicContact SD-CG2 4.35Å
298D91.3Very high87Confident64 Ų6471.8 Ų71.834%0.34234%0.341SS..  trans-68.2118.7173.8-174.66000110.3K294 N295 L296 S300 S303 R309K294-D298 PolarHBondContact O-N 2.56Å; N295-D298 WeakPolarHBondContact O-CB 3Å; N295-D298 PolarHBondContact O-N 3.37Å; N295-D298 VanDerWaalsContact O-N 3.13Å; L296-D298 VanDerWaalsContact C-N 3.31Å; D298-S300 WeakPolarHBondContact OD1-CB 3.08Å; D298-S300 PolarHBondContact OD1-N 3.17Å; D298-S303 VanDerWaalsContact OD2-CB 3.31Å; D298-S303 WeakPolarHBondContact OD2-CB 3.4Å; D298-S303 PolarHBondContact OD2-OG 3.36Å; D298-R309 VanDerWaalsContact O-CD 3.22Å; D298-R309 WeakPolarHBondContact O-CD 3.24Å
299T91.6Very high87Confident52 Ų5271.5 Ų71.532%0.31934%0.338SS..  trans-100.73.7-178.957.80000112.6L84 K85 M297 H301L84-T299 PolarHBondContact N-O 3.27Å; K85-T299 HydrophobicContact CG-CG2 4.39Å; M297-T299 PolarHBondContact O-N 3.48Å; T299-H301 PolarHBondContact O-N 3.11Å
300S86Confident87.1Confident46 Ų4669.8 Ų69.832%0.32233%0.33SS..  trans-66.3127.6-179.7179.40000111.8D298 K302 S303D298-S300 WeakPolarHBondContact OD1-CB 3.08Å; D298-S300 PolarHBondContact OD1-N 3.17Å; S300-K302 PolarHBondContact O-N 3.24Å; S300-K302 VanDerWaalsContact O-N 3.09Å; S300-K302 PolarHBondContact OG-N 3.3Å; S300-S303 PolarHBondContact O-N 2.98Å
301H74.8Confident87.3Confident74 Ų7465 Ų6534%0.34331%0.306SS..THydrogen-bonded Turntrans-65.7-11174.367.3-91.1000113.3T299 R306T299-H301 PolarHBondContact O-N 3.11Å; H301-R306 WeakPolarHBondContact O-CD 3.44Å; H301-R306 PolarHBondContact O-NH1 3.14Å
302K72.9Confident87.5Confident166 Ų16663.4 Ų63.472%0.72230%0.3SS*.THydrogen-bonded Turntrans-98-1.2179.5-60.2-173.7-179.9178.10113.8S300S300-K302 PolarHBondContact O-N 3.24Å; S300-K302 VanDerWaalsContact O-N 3.09Å; S300-K302 PolarHBondContact OG-N 3.3Å
303S73.4Confident87.8Confident25 Ų2563.1 Ų63.118%0.17530%0.295CS..  trans-64.3139.5-178.8-1740000111.5D298 S300 R305 R306D298-S303 VanDerWaalsContact OD2-CB 3.31Å; D298-S303 WeakPolarHBondContact OD2-CB 3.4Å; D298-S303 PolarHBondContact OD2-OG 3.36Å; S300-S303 PolarHBondContact O-N 2.98Å; S303-R305 VanDerWaalsContact C-N 3.28Å; S303-R305 PolarHBondContact O-N 3.41Å; S303-R305 PolarHBondContact OG-N 3.39Å; S303-R306 WeakPolarHBondContact O-CB 3.21Å; S303-R306 WeakPolarHBondContact O-CD 3.49Å; S303-R306 VanDerWaalsContact O-CG 3.3Å; S303-R306 WeakPolarHBondContact O-CG 3.18Å; S303-R306 PolarHBondContact O-N 3.03Å
304R66.8Low87.9Confident245 Ų24562.3 Ų62.393%0.92529%0.29SS*.THydrogen-bonded Turntrans-66.3-31.3174.8-79.4-178.565.5139.7-2.8112
305R69.8Low88.1Confident75 Ų7557.1 Ų57.128%0.28327%0.269SS..THydrogen-bonded Turntrans-96.618.4-179.4-64.6-166.5171174.9-3.4113.1E282 N295 S303 A307 E308E282-R305 IonicContact OE1-NH2 3.33Å; E282-R305 PolarHBondContact OE1-NH2 3.41Å; N295-R305 PolarHBondContact ND2-NH1 2.94Å; S303-R305 VanDerWaalsContact C-N 3.28Å; S303-R305 PolarHBondContact O-N 3.41Å; S303-R305 PolarHBondContact OG-N 3.39Å; R305-A307 VanDerWaalsContact C-N 3.29Å; R305-A307 PolarHBondContact O-N 3.39Å; R305-E308 WeakPolarHBondContact CB-OE1 3.43Å; R305-E308 WeakPolarHBondContact CD-OE1 3.23Å; R305-E308 VanDerWaalsContact CG-OE1 3.22Å; R305-E308 WeakPolarHBondContact CG-OE1 3.35Å; R305-E308 IonicContact NE-OE1 3.56Å; R305-E308 WeakPolarHBondContact O-CB 3.32Å; R305-E308 PolarHBondContact O-N 3.19Å; R305-E308 VanDerWaalsContact O-N 3.14Å
306R79.3Confident88.5Confident61 Ų6155.3 Ų55.323%0.2326%0.259CS..Hα-helixtrans-56.4-41.1-178.265-171.7176.6175.44.7112.3G76 L84 H301 S303 E308 R309 Q310G76-R306 PolarHBondContact O-NH1 2.64Å; G76-R306 PolarHBondContact O-NH2 3.44Å; L84-R306 HydrophobicContact CD1-CB 3.77Å; H301-R306 WeakPolarHBondContact O-CD 3.44Å; H301-R306 PolarHBondContact O-NH1 3.14Å; S303-R306 WeakPolarHBondContact O-CB 3.21Å; S303-R306 WeakPolarHBondContact O-CD 3.49Å; S303-R306 VanDerWaalsContact O-CG 3.3Å; S303-R306 WeakPolarHBondContact O-CG 3.18Å; S303-R306 PolarHBondContact O-N 3.03Å; R306-E308 PolarHBondContact O-N 2.83Å; R306-R309 PolarHBondContact O-N 2.75Å; R306-R309 VanDerWaalsContact O-N 3.16Å; R306-Q310 PolarHBondContact O-N 2.78Å; R306-Q310 PolarHBondContact O-NE2 2.71Å; R306-Q310 VanDerWaalsContact O-NE2 3.16Å; R306-Q310 PolarHBondContact O-OE1 3.23Å
307A91.2Very high88.7Confident32 Ų3255.5 Ų55.526%0.26426%0.261SS..Hα-helixtrans-58.1-34.4-17900000113Y75 R305 R309 Q310 W311Y75-A307 HydrophobicContact CD1-CB 4.24Å; Y75-A307 HydrophobicContact CE1-CB 4.37Å; R305-A307 VanDerWaalsContact C-N 3.29Å; R305-A307 PolarHBondContact O-N 3.39Å; A307-R309 PolarHBondContact O-N 2.96Å; A307-Q310 PolarHBondContact O-N 3.47Å; A307-W311 WeakPolarHBondContact O-CB 3.48Å; A307-W311 PolarHBondContact O-N 3.32Å
308E93.4Very high88.9Confident88 Ų8851.2 Ų51.241%0.41124%0.24SC..Hα-helixtrans-64.1-40.4179.5-64.3166.3-141.500112.1L296 R305 R306 T312L296-E308 HydrophobicContact CD2-CB 4.12Å; R305-E308 WeakPolarHBondContact CB-OE1 3.43Å; R305-E308 WeakPolarHBondContact CD-OE1 3.23Å; R305-E308 VanDerWaalsContact CG-OE1 3.22Å; R305-E308 WeakPolarHBondContact CG-OE1 3.35Å; R305-E308 IonicContact NE-OE1 3.56Å; R305-E308 WeakPolarHBondContact O-CB 3.32Å; R305-E308 PolarHBondContact O-N 3.19Å; R305-E308 VanDerWaalsContact O-N 3.14Å; R306-E308 PolarHBondContact O-N 2.83Å; E308-T312 VanDerWaalsContact O-CB 3.23Å; E308-T312 WeakPolarHBondContact O-CB 3.5Å; E308-T312 PolarHBondContact O-N 2.88Å; E308-T312 PolarHBondContact O-OG1 3.31Å
309R95.6Very high89.2Confident4 Ų448.2 Ų48.22%0.01522%0.224CC..Hα-helixtrans-63.1-48176.4179.1178.7170.772.85.8111.4L84 T86 L296 D298 R306 A307 T312 Y313 F349L84-R309 PolarHBondContact O-NE 3.03Å; L84-R309 PolarHBondContact O-NH2 3.21Å; T86-R309 PolarHBondContact OG1-NH2 2.9Å; L296-R309 HydrophobicContact CD2-CB 4.31Å; L296-R309 WeakPolarHBondContact O-CD 3.35Å; L296-R309 WeakPolarHBondContact O-CG 3.15Å; L296-R309 PolarHBondContact O-NH1 2.85Å; D298-R309 VanDerWaalsContact O-CD 3.22Å; D298-R309 WeakPolarHBondContact O-CD 3.24Å; R306-R309 PolarHBondContact O-N 2.75Å; R306-R309 VanDerWaalsContact O-N 3.16Å; A307-R309 PolarHBondContact O-N 2.96Å; R309-T312 PolarHBondContact O-N 2.78Å; R309-Y313 WeakPolarHBondContact O-CB 3.43Å; R309-Y313 PolarHBondContact O-N 3.31Å; R309-F349 HydrophobicContact CG-CE1 3.97Å; R309-F349 HydrophobicContact CG-CZ 4.05Å; R309-F349 WeakPolarHBondContact O-CZ 3.19Å
310Q96Very high89.5Confident1 Ų145.8 Ų45.81%0.00521%0.208CC..Hα-helixtrans-62.1-46.2178.2-77.385.3-80.500111.6F74 Y75 L84 L89 L92 R306 A307 T312 Y313 Q314F74-Q310 HydrophobicContact CB-CG 3.98Å; F74-Q310 WeakPolarHBondContact O-CG 3.36Å; F74-Q310 PolarHBondContact O-NE2 2.99Å; Y75-Q310 HydrophobicContact CD1-CB 4.33Å; Y75-Q310 HydrophobicContact CE1-CB 3.53Å; Y75-Q310 HydrophobicContact CE1-CG 4.33Å; Y75-Q310 HydrophobicContact CE2-CB 4.29Å; Y75-Q310 WeakPolarHBondContact OH-CB 3.43Å; L84-Q310 VanDerWaalsContact CD1-OE1 3.26Å; L84-Q310 HydrophobicContact CD2-CG 4.08Å; L89-Q310 HydrophobicContact CD2-CG 4.19Å; L92-Q310 HydrophobicContact CD2-CB 3.64Å; L92-Q310 HydrophobicContact CD2-CG 3.78Å; R306-Q310 PolarHBondContact O-N 2.78Å; R306-Q310 PolarHBondContact O-NE2 2.71Å; R306-Q310 VanDerWaalsContact O-NE2 3.16Å; R306-Q310 PolarHBondContact O-OE1 3.23Å; A307-Q310 PolarHBondContact O-N 3.47Å; Q310-T312 PolarHBondContact O-N 3.23Å; Q310-Y313 WeakPolarHBondContact O-CB 3.48Å; Q310-Y313 PolarHBondContact O-N 2.77Å; Q310-Q314 PolarHBondContact O-N 3.02Å
311W97.6Very high90Very high55 Ų5544.2 Ų44.221%0.20820%0.196CC..Hα-helixtrans-64.3-43.8-179.1-176.4-121.5000111.1E43 Y75 Y127 A307 Y313 Q314 T315 F319 F321E43-W311 HydrophobicContact CB-CD2 4.06Å; E43-W311 HydrophobicContact CB-CE3 3.6Å; E43-W311 HydrophobicContact CB-CG 4.47Å; E43-W311 HydrophobicContact CB-CZ3 4.15Å; E43-W311 HydrophobicContact CG-CD2 4.22Å; E43-W311 HydrophobicContact CG-CE3 4.15Å; Y75-W311 WeakPolarHBondContact OH-CA 3.4Å; Y75-W311 PolarHBondContact OH-N 3.07Å; Y127-W311 HydrophobicContact CD1-CH2 4.49Å; Y127-W311 AromaticContact CD1-CZ3 3.82Å; Y127-W311 HydrophobicContact CD1-CZ3 3.82Å; Y127-W311 HydrophobicContact CD2-CH2 4.4Å; Y127-W311 HydrophobicContact CD2-CZ3 4.23Å; Y127-W311 HydrophobicContact CE1-CZ3 4.34Å; Y127-W311 HydrophobicContact CG-CH2 4Å; Y127-W311 AromaticContact CG-CZ3 3.75Å; Y127-W311 HydrophobicContact CG-CZ3 3.75Å; A307-W311 WeakPolarHBondContact O-CB 3.48Å; A307-W311 PolarHBondContact O-N 3.32Å; W311-Y313 VanDerWaalsContact C-N 3.27Å; W311-Y313 PolarHBondContact O-N 3.48Å; W311-Q314 HydrophobicContact CE3-CB 4.34Å; W311-Q314 WeakPolarHBondContact O-CA 3.18Å; W311-Q314 PolarHBondContact O-N 3.4Å; W311-T315 WeakPolarHBondContact O-CG2 3.4Å; W311-T315 PolarHBondContact O-N 3.34Å; W311-F319 AromaticContact CH2-CD2 3.94Å; W311-F319 HydrophobicContact CH2-CD2 3.94Å; W311-F319 HydrophobicContact CH2-CE2 4.22Å; W311-F319 AromaticContact CZ3-CD2 3.98Å; W311-F319 HydrophobicContact CZ3-CD2 3.98Å; W311-F319 AromaticContact CZ3-CE2 3.93Å; W311-F319 HydrophobicContact CZ3-CE2 3.93Å; W311-F321 HydrophobicContact CH2-CD2 4.48Å; W311-F321 HydrophobicContact CH2-CE2 4.44Å; W311-F321 HydrophobicContact CZ2-CD2 4.16Å
312T97.6Very high91.1Very high24 Ų2441.3 Ų41.315%0.14718%0.182CC..Hα-helixtrans-62.8-35.1175.5-53.30000111.5E308 R309 Q310 T315 C316 I344 F349E308-T312 VanDerWaalsContact O-CB 3.23Å; E308-T312 WeakPolarHBondContact O-CB 3.5Å; E308-T312 PolarHBondContact O-N 2.88Å; E308-T312 PolarHBondContact O-OG1 3.31Å; R309-T312 PolarHBondContact O-N 2.78Å; Q310-T312 PolarHBondContact O-N 3.23Å; T312-T315 WeakPolarHBondContact CA-OG1 3.36Å; T312-T315 PolarHBondContact O-N 3.03Å; T312-T315 PolarHBondContact O-OG1 2.98Å; T312-C316 WeakPolarHBondContact O-CB 3.48Å; T312-C316 PolarHBondContact O-N 3.01Å; T312-C316 PolarHBondContact O-SG 2.79Å; T312-I344 HydrophobicContact CG2-CG1 4.43Å; T312-I344 HydrophobicContact CG2-CG2 3.79Å; T312-F349 HydrophobicContact CG2-CE2 3.88Å
313Y98.1Very high92.2Very high26 Ų2635.3 Ų35.310%0.10216%0.157CC..Hα-helixtrans-61.1-46.7171.7-178.7-94.1000111.1T86 L89 L92 R309 Q310 W311 T315 C316 T317 F349 I351T86-Y313 HydrophobicContact CG2-CE2 4.3Å; L89-Y313 HydrophobicContact CB-CD1 3.89Å; L89-Y313 HydrophobicContact CB-CD2 3.93Å; L89-Y313 HydrophobicContact CB-CE1 3.79Å; L89-Y313 HydrophobicContact CB-CE2 3.82Å; L89-Y313 HydrophobicContact CB-CG 3.94Å; L89-Y313 HydrophobicContact CD1-CD1 4.48Å; L89-Y313 HydrophobicContact CD1-CD2 3.83Å; L89-Y313 HydrophobicContact CD1-CE2 4.48Å; L89-Y313 HydrophobicContact CD1-CG 3.81Å; L89-Y313 HydrophobicContact CG-CG 4.46Å; L89-Y313 WeakPolarHBondContact O-CE1 3.48Å; L89-Y313 VanDerWaalsContact O-CZ 3.3Å; L89-Y313 PolarHBondContact O-OH 3.38Å; L92-Y313 HydrophobicContact CB-CD1 4.39Å; L92-Y313 HydrophobicContact CB-CE1 4.42Å; L92-Y313 HydrophobicContact CD2-CD1 4.2Å; L92-Y313 HydrophobicContact CG-CD1 4.4Å; R309-Y313 WeakPolarHBondContact O-CB 3.43Å; R309-Y313 PolarHBondContact O-N 3.31Å; Q310-Y313 WeakPolarHBondContact O-CB 3.48Å; Q310-Y313 PolarHBondContact O-N 2.77Å; W311-Y313 VanDerWaalsContact C-N 3.27Å; W311-Y313 PolarHBondContact O-N 3.48Å; Y313-T315 PolarHBondContact O-N 3.07Å; Y313-C316 CarbonylContact O-C 3.57Å; Y313-C316 WeakPolarHBondContact O-CA 3.37Å; Y313-C316 WeakPolarHBondContact O-CB 3.47Å; Y313-C316 PolarHBondContact O-N 3.26Å; Y313-C316 VanDerWaalsContact O-N 3.1Å; Y313-T317 HydrophobicContact CD1-CG2 4.14Å; Y313-T317 HydrophobicContact CD2-CG2 4.29Å; Y313-T317 HydrophobicContact CE1-CG2 3.7Å; Y313-T317 HydrophobicContact CE2-CG2 3.89Å; Y313-T317 HydrophobicContact CG-CG2 4.42Å; Y313-T317 WeakPolarHBondContact O-CG2 3.39Å; Y313-T317 PolarHBondContact O-N 3.45Å; Y313-T317 PolarHBondContact O-OG1 2.99Å; Y313-F349 HydrophobicContact CD2-CB 4.37Å; Y313-F349 AromaticContact CD2-CD1 3.65Å; Y313-F349 HydrophobicContact CD2-CD1 3.65Å; Y313-F349 HydrophobicContact CD2-CD2 4.39Å; Y313-F349 AromaticContact CD2-CE1 3.95Å; Y313-F349 HydrophobicContact CD2-CE1 3.95Å; Y313-F349 AromaticContact CD2-CG 3.89Å; Y313-F349 HydrophobicContact CD2-CG 3.89Å; Y313-F349 HydrophobicContact CD2-CZ 4.46Å; Y313-F349 HydrophobicContact CE2-CD1 4.47Å; Y313-F349 HydrophobicContact CG-CE1 4.43Å; Y313-I351 HydrophobicContact CD2-CD1 4.29Å; Y313-I351 HydrophobicContact CE2-CD1 4.05Å
314Q98.4Very high93.3Very high0 Ų034.1 Ų34.10%015%0.148CC..Hα-helixtrans-64.7-35.1177.9-66.8-168.6-98.700113.4Y75 L92 Y127 Q310 W311 C316 T317 E318 F319Y75-Q314 PolarHBondContact OH-OE1 2.91Å; L92-Q314 HydrophobicContact CD1-CG 4.26Å; L92-Q314 HydrophobicContact CD2-CG 3.98Å; L92-Q314 HydrophobicContact CG-CG 3.84Å; Y127-Q314 PolarHBondContact OH-NE2 2.82Å; Y127-Q314 VanDerWaalsContact OH-NE2 3.11Å; Q310-Q314 PolarHBondContact O-N 3.02Å; W311-Q314 HydrophobicContact CE3-CB 4.34Å; W311-Q314 WeakPolarHBondContact O-CA 3.18Å; W311-Q314 PolarHBondContact O-N 3.4Å; Q314-C316 VanDerWaalsContact C-N 3.32Å; Q314-T317 PolarHBondContact O-N 3.43Å; Q314-E318 PolarHBondContact NE2-OE2 3.26Å; Q314-E318 WeakPolarHBondContact O-CA 3.33Å; Q314-E318 PolarHBondContact O-N 2.94Å; Q314-F319 HydrophobicContact CB-CD2 3.88Å; Q314-F319 HydrophobicContact CB-CE2 3.79Å; Q314-F319 HydrophobicContact CG-CE2 4.47Å; Q314-F319 PolarHBondContact O-N 3.42Å; Q314-F319 VanDerWaalsContact O-N 3.07Å
315T98.2Very high94.6Very high13 Ų1322.8 Ų22.88%0.0811%0.106CC..Iπ-helixtrans-65.1-37.8171.7640000111.5W311 T312 Y313 G320W311-T315 WeakPolarHBondContact O-CG2 3.4Å; W311-T315 PolarHBondContact O-N 3.34Å; T312-T315 WeakPolarHBondContact CA-OG1 3.36Å; T312-T315 PolarHBondContact O-N 3.03Å; T312-T315 PolarHBondContact O-OG1 2.98Å; Y313-T315 PolarHBondContact O-N 3.07Å; T315-G320 WeakPolarHBondContact CB-O 3.45Å; T315-G320 WeakPolarHBondContact CG2-O 3.42Å; T315-G320 WeakPolarHBondContact O-CA 3.35Å; T315-G320 PolarHBondContact O-N 3.43Å
316C98.4Very high95.6Very high1 Ų124.3 Ų24.31%0.00712%0.117CC..Iπ-helixtrans-74.5-19.3175.2-64.90000114.4T312 Y313 Q314 C345 F349 I351 L356T312-C316 WeakPolarHBondContact O-CB 3.48Å; T312-C316 PolarHBondContact O-N 3.01Å; T312-C316 PolarHBondContact O-SG 2.79Å; Y313-C316 CarbonylContact O-C 3.57Å; Y313-C316 WeakPolarHBondContact O-CA 3.37Å; Y313-C316 WeakPolarHBondContact O-CB 3.47Å; Y313-C316 PolarHBondContact O-N 3.26Å; Y313-C316 VanDerWaalsContact O-N 3.1Å; Q314-C316 VanDerWaalsContact C-N 3.32Å; C316-C345 HydrophobicContact CB-CB 3.74Å; C316-C345 WeakPolarHBondContact CB-SG 3.33Å; C316-C345 WeakPolarHBondContact SG-CA 3.25Å; C316-C345 WeakPolarHBondContact SG-CB 3.08Å; C316-C345 CovalentContact SG-SG 2.04Å; C316-C345 PolarHBondContact SG-SG 2.82Å; C316-F349 HydrophobicContact CB-CD2 4.48Å; C316-I351 HydrophobicContact CB-CD1 3.93Å; C316-L356 HydrophobicContact CB-CD2 4.42Å; C316-L356 WeakPolarHBondContact O-CD2 3.37Å
317T98.2Very high96Very high16 Ų1624.7 Ų24.710%0.09812%0.123CC..Iπ-helixtrans-113-24.3-175.756.50000115.7Y313 Q314 I351 R359Y313-T317 HydrophobicContact CD1-CG2 4.14Å; Y313-T317 HydrophobicContact CD2-CG2 4.29Å; Y313-T317 HydrophobicContact CE1-CG2 3.7Å; Y313-T317 HydrophobicContact CE2-CG2 3.89Å; Y313-T317 HydrophobicContact CG-CG2 4.42Å; Y313-T317 WeakPolarHBondContact O-CG2 3.39Å; Y313-T317 PolarHBondContact O-N 3.45Å; Y313-T317 PolarHBondContact O-OG1 2.99Å; Q314-T317 PolarHBondContact O-N 3.43Å; T317-I351 HydrophobicContact CG2-CD1 3.54Å; T317-R359 WeakPolarHBondContact O-CB 3.35Å
318E98.4Very high95.7Very high8 Ų829.8 Ų29.84%0.03715%0.151CC..Iπ-helixtrans-135.1-45.8-171-61.8-171.295.300113.2S93 S94 Q95 Q314 T363S93-E318 VanDerWaalsContact CA-OE2 3.3Å; S93-E318 WeakPolarHBondContact CA-OE2 3.43Å; S94-E318 WeakPolarHBondContact CB-OE1 3.37Å; S94-E318 PolarHBondContact N-OE1 2.93Å; S94-E318 PolarHBondContact N-OE2 2.98Å; S94-E318 PolarHBondContact OG-OE1 2.79Å; Q95-E318 PolarHBondContact OE1-OE1 3.39Å; Q95-E318 VanDerWaalsContact OE1-OE1 3.09Å; Q314-E318 PolarHBondContact NE2-OE2 3.26Å; Q314-E318 WeakPolarHBondContact O-CA 3.33Å; Q314-E318 PolarHBondContact O-N 2.94Å; E318-T363 WeakPolarHBondContact CA-OG1 3.44Å; E318-T363 VanDerWaalsContact O-CB 3.29Å; E318-T363 WeakPolarHBondContact O-CB 3.46Å; E318-T363 PolarHBondContact O-OG1 3.11Å
319F98.3Very high95.4Very high1 Ų128.6 Ų28.60%0.00415%0.15CC..Iπ-helixtrans-108.4-35.8-158.1-57-45.3000115.8Y127 W134 K156 W311 Q314 F321 T363Y127-F319 HydrophobicContact CD2-CE2 4.03Å; Y127-F319 HydrophobicContact CD2-CZ 4.01Å; Y127-F319 HydrophobicContact CE2-CE1 4.46Å; Y127-F319 AromaticContact CE2-CE2 3.7Å; Y127-F319 HydrophobicContact CE2-CE2 3.7Å; Y127-F319 AromaticContact CE2-CZ 3.45Å; Y127-F319 HydrophobicContact CE2-CZ 3.45Å; Y127-F319 VanDerWaalsContact CE2-CZ 3.45Å; W134-F319 AromaticContact CH2-CE1 3.73Å; W134-F319 HydrophobicContact CH2-CE1 3.73Å; W134-F319 HydrophobicContact CH2-CZ 4.29Å; W134-F319 HydrophobicContact CZ3-CE1 4.16Å; W134-F319 HydrophobicContact CZ3-CZ 4.35Å; K156-F319 CarbonylContact C-O 3.51Å; K156-F319 PolarHBondContact N-O 2.81Å; W311-F319 AromaticContact CH2-CD2 3.94Å; W311-F319 HydrophobicContact CH2-CD2 3.94Å; W311-F319 HydrophobicContact CH2-CE2 4.22Å; W311-F319 AromaticContact CZ3-CD2 3.98Å; W311-F319 HydrophobicContact CZ3-CD2 3.98Å; W311-F319 AromaticContact CZ3-CE2 3.93Å; W311-F319 HydrophobicContact CZ3-CE2 3.93Å; Q314-F319 HydrophobicContact CB-CD2 3.88Å; Q314-F319 HydrophobicContact CB-CE2 3.79Å; Q314-F319 HydrophobicContact CG-CE2 4.47Å; Q314-F319 PolarHBondContact O-N 3.42Å; Q314-F319 VanDerWaalsContact O-N 3.07Å; F319-F321 HydrophobicContact CB-CD1 4.46Å; F319-F321 HydrophobicContact CB-CD2 3.67Å; F319-F321 HydrophobicContact CB-CE1 4.27Å; F319-F321 HydrophobicContact CB-CE2 3.48Å; F319-F321 VanDerWaalsContact CB-CE2 3.48Å; F319-F321 HydrophobicContact CB-CG 4.18Å; F319-F321 HydrophobicContact CB-CZ 3.81Å; F319-F321 HydrophobicContact CD1-CE2 4.45Å; F319-F321 HydrophobicContact CD1-CZ 4.46Å; F319-F321 HydrophobicContact CD2-CE2 4.38Å; F319-F321 HydrophobicContact CG-CD2 4.43Å; F319-F321 AromaticContact CG-CE2 3.88Å; F319-F321 HydrophobicContact CG-CE2 3.88Å; F319-F321 HydrophobicContact CG-CZ 4.26Å; F319-F321 PolarHBondContact O-N 2.91Å; F319-T363 HydrophobicContact CD1-CG2 4.02Å; F319-T363 HydrophobicContact CE1-CG2 4.03Å
320G96.9Very high95.3Very high0 Ų028.9 Ų28.90%015%0.153CC..EExtended strand (participates in β ladder)trans67.4-117.4-159.700000110.1K156 T315K156-G320 CarbonylContact O-C 3.57Å; T315-G320 WeakPolarHBondContact CB-O 3.45Å; T315-G320 WeakPolarHBondContact CG2-O 3.42Å; T315-G320 WeakPolarHBondContact O-CA 3.35Å; T315-G320 PolarHBondContact O-N 3.43Å
321F97.6Very high95.3Very high14 Ų1428.9 Ų28.96%0.06115%0.153CC..EExtended strand (participates in β ladder)trans7432.5-173.9-48.9-31.9000113.9P152 K154 K156 W311 F319 Q323 W387 L390P152-F321 HydrophobicContact CB-CE2 4.44Å; P152-F321 HydrophobicContact CB-CZ 4.04Å; P152-F321 HydrophobicContact CG-CE2 4.32Å; P152-F321 HydrophobicContact CG-CZ 4.35Å; K154-F321 WeakPolarHBondContact O-CE1 3.21Å; K156-F321 PolarHBondContact O-N 3.48Å; W311-F321 HydrophobicContact CH2-CD2 4.48Å; W311-F321 HydrophobicContact CH2-CE2 4.44Å; W311-F321 HydrophobicContact CZ2-CD2 4.16Å; F319-F321 HydrophobicContact CB-CD1 4.46Å; F319-F321 HydrophobicContact CB-CD2 3.67Å; F319-F321 HydrophobicContact CB-CE1 4.27Å; F319-F321 HydrophobicContact CB-CE2 3.48Å; F319-F321 VanDerWaalsContact CB-CE2 3.48Å; F319-F321 HydrophobicContact CB-CG 4.18Å; F319-F321 HydrophobicContact CB-CZ 3.81Å; F319-F321 HydrophobicContact CD1-CE2 4.45Å; F319-F321 HydrophobicContact CD1-CZ 4.46Å; F319-F321 HydrophobicContact CD2-CE2 4.38Å; F319-F321 HydrophobicContact CG-CD2 4.43Å; F319-F321 AromaticContact CG-CE2 3.88Å; F319-F321 HydrophobicContact CG-CE2 3.88Å; F319-F321 HydrophobicContact CG-CZ 4.26Å; F319-F321 PolarHBondContact O-N 2.91Å; F321-Q323 PolarHBondContact O-N 3.41Å; F321-W387 HydrophobicContact CB-CH2 3.76Å; F321-W387 HydrophobicContact CB-CZ3 3.9Å; F321-W387 HydrophobicContact CD1-CZ3 4.11Å; F321-W387 AromaticContact CD2-CH2 3.9Å; F321-W387 HydrophobicContact CD2-CH2 3.9Å; F321-W387 AromaticContact CD2-CZ3 3.74Å; F321-W387 HydrophobicContact CD2-CZ3 3.74Å; F321-W387 HydrophobicContact CE2-CZ3 4.18Å; F321-W387 AromaticContact CG-CH2 3.96Å; F321-W387 HydrophobicContact CG-CH2 3.96Å; F321-W387 AromaticContact CG-CZ3 3.69Å; F321-W387 HydrophobicContact CG-CZ3 3.69Å; F321-L390 HydrophobicContact CD1-CD1 3.49Å; F321-L390 VanDerWaalsContact CD1-CD1 3.49Å; F321-L390 HydrophobicContact CE1-CD1 3.48Å; F321-L390 VanDerWaalsContact CE1-CD1 3.48Å; F321-L390 HydrophobicContact CG-CD1 4.46Å; F321-L390 HydrophobicContact CZ-CD1 4.41Å
322Y97.4Very high95.2Very high13 Ų1327.2 Ų27.25%0.05115%0.147CC..EExtended strand (participates in β ladder)trans-71.5113.1174.4-61.6-60.9000109.5L157 F159 T324 L338 Q341 T342 C345 L356L157-Y322 HydrophobicContact CD1-CD2 3.73Å; L157-Y322 HydrophobicContact CD1-CE2 3.67Å; L157-Y322 WeakPolarHBondContact O-CB 3.43Å; L157-Y322 WeakPolarHBondContact O-CD2 3.43Å; L157-Y322 PolarHBondContact O-N 3.47Å; F159-Y322 WeakPolarHBondContact CA-O 3.48Å; F159-Y322 PolarHBondContact N-O 3.41Å; Y322-T324 PolarHBondContact O-N 2.63Å; Y322-L338 HydrophobicContact CD2-CD1 3.7Å; Y322-L338 HydrophobicContact CG-CD1 3.98Å; Y322-Q341 HydrophobicContact CD1-CB 3.74Å; Y322-Q341 HydrophobicContact CE1-CB 4.45Å; Y322-Q341 HydrophobicContact CG-CB 4.24Å; Y322-T342 HydrophobicContact CD2-CG2 3.64Å; Y322-T342 HydrophobicContact CE2-CG2 3.5Å; Y322-T342 HydrophobicContact CG-CG2 4.26Å; Y322-C345 PolarHBondContact OH-SG 3.3Å; Y322-L356 HydrophobicContact CE2-CD1 4.35Å
323Q96.1Very high95.1Very high39 Ų3926.1 Ų26.118%0.18214%0.141CC..  trans-8592.1-176.1-66.6154.6-2.300108.3Y162 M232 F321 V336 Q341Y162-Q323 HydrophobicContact CD1-CG 4.16Å; Y162-Q323 HydrophobicContact CD2-CG 3.96Å; Y162-Q323 HydrophobicContact CE2-CG 4.49Å; Y162-Q323 HydrophobicContact CG-CB 4.5Å; Y162-Q323 HydrophobicContact CG-CG 3.79Å; M232-Q323 HydrophobicContact CE-CB 3.88Å; M232-Q323 HydrophobicContact CE-CG 4.18Å; F321-Q323 PolarHBondContact O-N 3.41Å; Q323-V336 WeakPolarHBondContact O-CG1 3.45Å; Q323-Q341 PolarHBondContact O-NE2 3.16Å
324T95.2Very high94.8Very high0 Ų027 Ų270%016%0.157CC..  trans-98.2171-17471.20000111.9D158 S160 S163 Y322 L338D158-T324 WeakPolarHBondContact OD1-CB 2.96Å; D158-T324 WeakPolarHBondContact OD1-CG2 3.38Å; D158-T324 PolarHBondContact OD1-OG1 3.08Å; S160-T324 WeakPolarHBondContact CB-OG1 3.32Å; S163-T324 PolarHBondContact OG-O 3.21Å; S163-T324 VanDerWaalsContact OG-O 3.14Å; Y322-T324 PolarHBondContact O-N 2.63Å; T324-L338 HydrophobicContact CG2-CB 3.9Å; T324-L338 HydrophobicContact CG2-CD1 4.27Å
325C94.9Very high94.5Very high7 Ų729.2 Ų29.25%0.04717%0.168CC..  trans-136.224.6-179.2-1660000112.2D327 C330 S333 G334 V336C325-D327 PolarHBondContact O-N 2.01Å; C325-C330 WeakPolarHBondContact CA-SG 3.38Å; C325-C330 HydrophobicContact CB-CB 3.93Å; C325-C330 WeakPolarHBondContact CB-SG 3.42Å; C325-C330 WeakPolarHBondContact SG-CB 3.32Å; C325-C330 CovalentContact SG-SG 2.01Å; C325-C330 PolarHBondContact SG-SG 3.39Å; C325-S333 VanDerWaalsContact CB-O 3.24Å; C325-S333 WeakPolarHBondContact CB-O 3.4Å; C325-S333 PolarHBondContact SG-O 3.45Å; C325-S333 VanDerWaalsContact SG-O 3.39Å; C325-G334 WeakPolarHBondContact O-CA 3.4Å; C325-V336 HydrophobicContact CB-CB 4Å; C325-V336 PolarHBondContact N-O 3.16Å
326E90.8Very high94.3Very high107 Ų10728.8 Ų28.850%0.517%0.165SC..  trans-71.7-17.8179.2-67.4179.289.100112.5T337 L338E326-T337 HydrophobicContact CG-CG2 3.87Å; E326-T337 WeakPolarHBondContact OE2-CA 3.27Å; E326-L338 PolarHBondContact OE2-N 3.4Å
327D87.9Confident94.1Very high69 Ų6930.2 Ų30.237%0.36917%0.174SC..SBendtrans-79.1135.2174.3-168.1-47.9000111.7C325 T329 C330C325-D327 PolarHBondContact O-N 2.01Å; D327-T329 PolarHBondContact O-N 2.8Å; D327-T329 WeakPolarHBondContact OD1-CB 3.2Å; D327-T329 PolarHBondContact OD1-N 2.84Å; D327-T329 PolarHBondContact OD1-OG1 3.28Å; D327-C330 WeakPolarHBondContact O-CB 3.45Å; D327-C330 PolarHBondContact O-N 3.21Å
328T84.3Confident94Very high139 Ų13931.1 Ų31.185%0.85318%0.178SC*.THydrogen-bonded Turntrans-55-20.7174.959.30000115.6C330T328-C330 VanDerWaalsContact C-N 3.34Å
329T87.5Confident93.7Very high63 Ų6336.9 Ų36.939%0.38721%0.205SC..THydrogen-bonded Turntrans-78-21.8178.350.60000112.7N164 R186 D327N164-T329 VanDerWaalsContact CG-OG1 3.23Å; N164-T329 PolarHBondContact ND2-OG1 2.77Å; N164-T329 WeakPolarHBondContact OD1-CB 3.41Å; N164-T329 PolarHBondContact OD1-OG1 3.14Å; R186-T329 PolarHBondContact NH2-O 3.19Å; D327-T329 PolarHBondContact O-N 2.8Å; D327-T329 WeakPolarHBondContact OD1-CB 3.2Å; D327-T329 PolarHBondContact OD1-N 2.84Å; D327-T329 PolarHBondContact OD1-OG1 3.28Å
330C94.1Very high93.3Very high11 Ų1137.4 Ų37.47%0.07421%0.21CC..  trans-58.9136.4178.8-1790000111.5S163 N164 C325 D327 T328 F332S163-C330 WeakPolarHBondContact CB-SG 3.35Å; N164-C330 PolarHBondContact OD1-N 2.78Å; C325-C330 WeakPolarHBondContact CA-SG 3.38Å; C325-C330 HydrophobicContact CB-CB 3.93Å; C325-C330 WeakPolarHBondContact CB-SG 3.42Å; C325-C330 WeakPolarHBondContact SG-CB 3.32Å; C325-C330 CovalentContact SG-SG 2.01Å; C325-C330 PolarHBondContact SG-SG 3.39Å; D327-C330 WeakPolarHBondContact O-CB 3.45Å; D327-C330 PolarHBondContact O-N 3.21Å; T328-C330 VanDerWaalsContact C-N 3.34Å; C330-F332 VanDerWaalsContact C-N 3.3Å; C330-F332 PolarHBondContact O-N 3.13Å; C330-F332 PolarHBondContact SG-N 3.34Å
331P95.1Very high93.1Very high1 Ų139 Ų391%0.00622%0.217CC..SBendtrans-81.4-5.8-179.933.2-36.6000114.6S163 L182 R186S163-P331 WeakPolarHBondContact O-CD 3.48Å; L182-P331 HydrophobicContact CD1-CB 3.67Å; R186-P331 HydrophobicContact CG-CB 4.14Å
332F96.3Very high93.1Very high20 Ų2038.7 Ų38.79%0.08822%0.216CC..SBendtrans-107.1-152.9-172.4-48-57.4000111.7V166 V185 F189 A228 I231 M232 C330V166-F332 HydrophobicContact CG1-CE2 4.13Å; V166-F332 HydrophobicContact CG1-CZ 3.63Å; V185-F332 HydrophobicContact CG1-CE1 4.27Å; F189-F332 HydrophobicContact CD1-CB 3.86Å; F189-F332 HydrophobicContact CD1-CD1 4.28Å; F189-F332 HydrophobicContact CD2-CD1 4.02Å; F189-F332 HydrophobicContact CE1-CB 3.9Å; F189-F332 AromaticContact CE1-CD1 3.89Å; F189-F332 HydrophobicContact CE1-CD1 3.89Å; F189-F332 HydrophobicContact CE1-CG 4.27Å; F189-F332 AromaticContact CE2-CD1 3.63Å; F189-F332 HydrophobicContact CE2-CD1 3.63Å; F189-F332 HydrophobicContact CE2-CE1 4.15Å; F189-F332 HydrophobicContact CG-CB 4.36Å; F189-F332 HydrophobicContact CG-CD1 4.35Å; F189-F332 HydrophobicContact CZ-CB 4.44Å; F189-F332 AromaticContact CZ-CD1 3.55Å; F189-F332 HydrophobicContact CZ-CD1 3.55Å; F189-F332 HydrophobicContact CZ-CE1 4.18Å; F189-F332 HydrophobicContact CZ-CG 4.35Å; A228-F332 HydrophobicContact CB-CB 4.15Å; A228-F332 HydrophobicContact CB-CD1 4.11Å; A228-F332 HydrophobicContact CB-CD2 3.86Å; A228-F332 HydrophobicContact CB-CE1 4.45Å; A228-F332 HydrophobicContact CB-CE2 4.22Å; A228-F332 HydrophobicContact CB-CG 3.78Å; A228-F332 HydrophobicContact CB-CZ 4.48Å; I231-F332 HydrophobicContact CB-CE1 3.9Å; I231-F332 HydrophobicContact CB-CZ 4.12Å; I231-F332 HydrophobicContact CD1-CE1 4.1Å; I231-F332 HydrophobicContact CG2-CE1 3.81Å; I231-F332 HydrophobicContact CG2-CZ 3.89Å; M232-F332 HydrophobicContact CG-CE2 3.6Å; M232-F332 HydrophobicContact CG-CZ 3.77Å; M232-F332 HydrophobicContact SD-CD2 4.42Å; M232-F332 HydrophobicContact SD-CE2 3.86Å; M232-F332 HydrophobicContact SD-CZ 4.47Å; C330-F332 VanDerWaalsContact C-N 3.3Å; C330-F332 PolarHBondContact O-N 3.13Å; C330-F332 PolarHBondContact SG-N 3.34Å
333S94.1Very high92.9Very high1 Ų142.1 Ų42.11%0.00723%0.232CC..  trans-95.9135.4-179.2175.80000112.7E193 C325 M335 V336E193-S333 WeakPolarHBondContact OE2-CB 3.36Å; E193-S333 PolarHBondContact OE2-OG 3.25Å; C325-S333 VanDerWaalsContact CB-O 3.24Å; C325-S333 WeakPolarHBondContact CB-O 3.4Å; C325-S333 PolarHBondContact SG-O 3.45Å; C325-S333 VanDerWaalsContact SG-O 3.39Å; S333-M335 PolarHBondContact O-N 3.48Å; S333-M335 VanDerWaalsContact O-N 3.08Å; S333-M335 WeakPolarHBondContact OG-CB 3.22Å; S333-M335 WeakPolarHBondContact OG-CG 3.17Å; S333-M335 PolarHBondContact OG-N 3.49Å; S333-V336 PolarHBondContact O-N 3.39Å
334G93.3Very high92.9Very high43 Ų4341.2 Ų41.244%0.44323%0.228SC..THydrogen-bonded Turntrans-66.4-3173.400000114.6C325 V336 T337C325-G334 WeakPolarHBondContact O-CA 3.4Å; G334-V336 PolarHBondContact O-N 2.99Å; G334-T337 WeakPolarHBondContact O-CG2 3.06Å
335M92.1Very high93Very high48 Ų4841.2 Ų41.224%0.23623%0.228CC..THydrogen-bonded Turntrans-62.8-24.4168.6-69.5-176.8136.100112.5E193 M224 S333 T337E193-M335 HydrophobicContact CG-SD 4.31Å; M224-M335 HydrophobicContact CG-SD 3.85Å; S333-M335 PolarHBondContact O-N 3.48Å; S333-M335 VanDerWaalsContact O-N 3.08Å; S333-M335 WeakPolarHBondContact OG-CB 3.22Å; S333-M335 WeakPolarHBondContact OG-CG 3.17Å; S333-M335 PolarHBondContact OG-N 3.49Å; M335-T337 PolarHBondContact O-N 3.44Å
336V93.1Very high93.1Very high3 Ų344.1 Ų44.12%0.01825%0.245CC..  trans-80.186.9179.5-176.40000110.1M224 Q225 Q323 C325 S333 G334M224-V336 HydrophobicContact CB-CG2 4.39Å; Q225-V336 HydrophobicContact CB-CG2 4.43Å; Q323-V336 WeakPolarHBondContact O-CG1 3.45Å; C325-V336 HydrophobicContact CB-CB 4Å; C325-V336 PolarHBondContact N-O 3.16Å; S333-V336 PolarHBondContact O-N 3.39Å; G334-V336 PolarHBondContact O-N 2.99Å
337T94.3Very high93.4Very high31 Ų3146 Ų4619%0.1925%0.252CS..  trans-105152.1-173.365.90000113.5E326 G334 M335 Q339 A340 Q341E326-T337 HydrophobicContact CG-CG2 3.87Å; E326-T337 WeakPolarHBondContact OE2-CA 3.27Å; G334-T337 WeakPolarHBondContact O-CG2 3.06Å; M335-T337 PolarHBondContact O-N 3.44Å; T337-Q339 VanDerWaalsContact C-N 3.28Å; T337-Q339 PolarHBondContact O-N 3.4Å; T337-A340 PolarHBondContact O-N 3.44Å; T337-A340 WeakPolarHBondContact OG1-CB 3.06Å; T337-A340 PolarHBondContact OG1-N 2.83Å; T337-Q341 PolarHBondContact O-N 3.43Å; T337-Q341 VanDerWaalsContact O-N 3.15Å
338L95.5Very high93.8Very high36 Ų3643 Ų4319%0.18824%0.236CC..Hα-helixtrans-59.5-41.3173.4-176.764.8000111.6L157 D158 Y322 T324 E326 A340 Q341 T342L157-L338 HydrophobicContact CD1-CD1 4.4Å; L157-L338 HydrophobicContact CD2-CD2 4.23Å; L157-L338 HydrophobicContact CG-CD1 4.13Å; L157-L338 HydrophobicContact CG-CD2 4.24Å; D158-L338 HydrophobicContact CB-CD1 4.12Å; D158-L338 HydrophobicContact CB-CD2 3.96Å; Y322-L338 HydrophobicContact CD2-CD1 3.7Å; Y322-L338 HydrophobicContact CG-CD1 3.98Å; T324-L338 HydrophobicContact CG2-CB 3.9Å; T324-L338 HydrophobicContact CG2-CD1 4.27Å; E326-L338 PolarHBondContact OE2-N 3.4Å; L338-A340 VanDerWaalsContact C-N 3.28Å; L338-A340 PolarHBondContact O-N 3.06Å; L338-Q341 PolarHBondContact O-N 3.16Å; L338-T342 HydrophobicContact CD1-CG2 3.83Å; L338-T342 HydrophobicContact CG-CG2 4.14Å; L338-T342 WeakPolarHBondContact O-CB 3.44Å; L338-T342 VanDerWaalsContact O-CG2 3.28Å; L338-T342 WeakPolarHBondContact O-CG2 3.44Å; L338-T342 PolarHBondContact O-N 3.17Å; L338-T342 PolarHBondContact O-OG1 3.42Å
339Q93.1Very high94.4Very high129 Ų12937.1 Ų37.160%0.60320%0.199SC*.Hα-helixtrans-59.3-43.6-178.4-173.6-17634.400110.8T337 T342 K343T337-Q339 VanDerWaalsContact C-N 3.28Å; T337-Q339 PolarHBondContact O-N 3.4Å; Q339-T342 PolarHBondContact O-OG1 3.02Å; Q339-K343 WeakPolarHBondContact O-CG 3.49Å; Q339-K343 PolarHBondContact O-N 2.97Å
340A90.4Very high94.9Very high12 Ų1237.1 Ų37.110%0.09921%0.211CC..Hα-helixtrans-72.7-43.5-177.800000111.9M221 T337 L338 T342 K343M221-A340 HydrophobicContact CE-CB 4.29Å; M221-A340 HydrophobicContact SD-CB 3.16Å; M221-A340 WeakPolarHBondContact SD-CB 3.31Å; T337-A340 PolarHBondContact O-N 3.44Å; T337-A340 WeakPolarHBondContact OG1-CB 3.06Å; T337-A340 PolarHBondContact OG1-N 2.83Å; L338-A340 VanDerWaalsContact C-N 3.28Å; L338-A340 PolarHBondContact O-N 3.06Å; A340-T342 VanDerWaalsContact C-N 3.33Å; A340-T342 PolarHBondContact O-N 3.16Å; A340-K343 WeakPolarHBondContact O-CB 3.06Å; A340-K343 PolarHBondContact O-N 3.33Å
341Q92.9Very high95Very high34 Ų3437.4 Ų37.416%0.15921%0.212CC..Hα-helixtrans-61.5-39.5176.7-68.7-171.91800112.3Y322 Q323 T337 L338 K343 I344Y322-Q341 HydrophobicContact CD1-CB 3.74Å; Y322-Q341 HydrophobicContact CE1-CB 4.45Å; Y322-Q341 HydrophobicContact CG-CB 4.24Å; Q323-Q341 PolarHBondContact O-NE2 3.16Å; T337-Q341 PolarHBondContact O-N 3.43Å; T337-Q341 VanDerWaalsContact O-N 3.15Å; L338-Q341 PolarHBondContact O-N 3.16Å; Q341-K343 VanDerWaalsContact C-N 3.32Å; Q341-K343 PolarHBondContact O-N 3.1Å; Q341-I344 VanDerWaalsContact O-CG2 3.23Å; Q341-I344 WeakPolarHBondContact O-CG2 3.21Å
342T95.9Very high95.1Very high7 Ų740 Ų404%0.04323%0.23CC..Hα-helixtrans-76.1-12.6-178.456.30000114.5L157 Y322 L338 Q339 A340 I344 C345 Q353 L356L157-T342 HydrophobicContact CD1-CG2 4.33Å; Y322-T342 HydrophobicContact CD2-CG2 3.64Å; Y322-T342 HydrophobicContact CE2-CG2 3.5Å; Y322-T342 HydrophobicContact CG-CG2 4.26Å; L338-T342 HydrophobicContact CD1-CG2 3.83Å; L338-T342 HydrophobicContact CG-CG2 4.14Å; L338-T342 WeakPolarHBondContact O-CB 3.44Å; L338-T342 VanDerWaalsContact O-CG2 3.28Å; L338-T342 WeakPolarHBondContact O-CG2 3.44Å; L338-T342 PolarHBondContact O-N 3.17Å; L338-T342 PolarHBondContact O-OG1 3.42Å; Q339-T342 PolarHBondContact O-OG1 3.02Å; A340-T342 VanDerWaalsContact C-N 3.33Å; A340-T342 PolarHBondContact O-N 3.16Å; T342-I344 PolarHBondContact O-N 3.18Å; T342-C345 WeakPolarHBondContact O-CB 3.47Å; T342-C345 PolarHBondContact O-N 3.18Å; T342-Q353 VanDerWaalsContact C-NE2 3.34Å; T342-Q353 WeakPolarHBondContact O-CG 3.47Å; T342-Q353 PolarHBondContact O-NE2 3.44Å; T342-L356 HydrophobicContact CG2-CD1 3.67Å
343K95Very high95Very high85 Ų8541.9 Ų41.937%0.3724%0.239SC..Hα-helixtrans-59.3-31.6173.7-77.8170.6-171.6173.90112.2Q339 A340 Q341 C345 T346 K347 Q353Q339-K343 WeakPolarHBondContact O-CG 3.49Å; Q339-K343 PolarHBondContact O-N 2.97Å; A340-K343 WeakPolarHBondContact O-CB 3.06Å; A340-K343 PolarHBondContact O-N 3.33Å; Q341-K343 VanDerWaalsContact C-N 3.32Å; Q341-K343 PolarHBondContact O-N 3.1Å; K343-C345 PolarHBondContact O-N 2.76Å; K343-T346 PolarHBondContact O-N 2.94Å; K343-K347 WeakPolarHBondContact O-CB 3.43Å; K343-K347 PolarHBondContact O-N 2.03Å; K343-Q353 VanDerWaalsContact N-NE2 3.17Å
344I95.6Very high95.1Very high20 Ų2050.1 Ų50.110%0.10328%0.277CS..Hα-helixtrans-60.5-34.7-178.7-157.665.8000111.9V293 L296 T312 Q341 T342 T346 K347 V348V293-I344 HydrophobicContact CB-CD1 4.5Å; V293-I344 HydrophobicContact CG2-CD1 3.7Å; L296-I344 HydrophobicContact CD1-CD1 3.7Å; L296-I344 HydrophobicContact CD1-CG1 3.56Å; T312-I344 HydrophobicContact CG2-CG1 4.43Å; T312-I344 HydrophobicContact CG2-CG2 3.79Å; Q341-I344 VanDerWaalsContact O-CG2 3.23Å; Q341-I344 WeakPolarHBondContact O-CG2 3.21Å; T342-I344 PolarHBondContact O-N 3.18Å; I344-T346 PolarHBondContact O-N 3.46Å; I344-K347 PolarHBondContact O-N 3.46Å; I344-V348 HydrophobicContact CD1-CG2 3.43Å; I344-V348 VanDerWaalsContact CD1-CG2 3.43Å; I344-V348 HydrophobicContact CG1-CG2 3.69Å; I344-V348 VanDerWaalsContact O-CB 3.32Å; I344-V348 WeakPolarHBondContact O-CB 3.42Å; I344-V348 PolarHBondContact O-N 2.83Å
345C97.8Very high95.3Very high0 Ų049.5 Ų49.50%027%0.266CS..Hα-helixtrans-60.3-45.5179.1-61.30000112.4C316 Y322 T342 K343 F349 G350 I351C316-C345 HydrophobicContact CB-CB 3.74Å; C316-C345 WeakPolarHBondContact CB-SG 3.33Å; C316-C345 WeakPolarHBondContact SG-CA 3.25Å; C316-C345 WeakPolarHBondContact SG-CB 3.08Å; C316-C345 CovalentContact SG-SG 2.04Å; C316-C345 PolarHBondContact SG-SG 2.82Å; Y322-C345 PolarHBondContact OH-SG 3.3Å; T342-C345 WeakPolarHBondContact O-CB 3.47Å; T342-C345 PolarHBondContact O-N 3.18Å; K343-C345 PolarHBondContact O-N 2.76Å; C345-F349 CarbonylContact O-C 3.57Å; C345-F349 WeakPolarHBondContact O-CB 3.24Å; C345-F349 PolarHBondContact O-N 3.43Å; C345-F349 VanDerWaalsContact O-N 3.13Å; C345-G350 PolarHBondContact O-N 3.45Å; C345-I351 CarbonylContact C-O 3.4Å; C345-I351 HydrophobicContact CB-CB 4.28Å; C345-I351 PolarHBondContact O-N 3.47Å
346T96.9Very high95.6Very high68 Ų6847.3 Ų47.342%0.41726%0.255SS..Hα-helixtrans-72.9-41.8178.2-56.60000110.6K343 I344 G350 I351K343-T346 PolarHBondContact O-N 2.94Å; I344-T346 PolarHBondContact O-N 3.46Å; T346-G350 VanDerWaalsContact O-CA 3.27Å; T346-G350 WeakPolarHBondContact O-CA 3.27Å; T346-G350 PolarHBondContact O-N 2.97Å; T346-G350 VanDerWaalsContact O-N 3.08Å; T346-I351 WeakPolarHBondContact CA-O 3.48Å; T346-I351 WeakPolarHBondContact CB-O 3.46Å; T346-I351 PolarHBondContact N-O 3.1Å; T346-I351 VanDerWaalsContact N-O 3.11Å; T346-I351 PolarHBondContact OG1-O 3.28Å
347K96.3Very high95.8Very high145 Ų14550.5 Ų50.563%0.6328%0.276SS*.Hα-helixtrans-68.1-42.2-175.9-172.764.6175.2-172.60113.2V293 K343 I344V293-K347 HydrophobicContact CG1-CG 3.84Å; V293-K347 HydrophobicContact CG2-CG 4.48Å; K343-K347 WeakPolarHBondContact O-CB 3.43Å; K343-K347 PolarHBondContact O-N 2.03Å; I344-K347 PolarHBondContact O-N 3.46Å
348V96.3Very high96Very high7 Ų752.7 Ų52.74%0.04229%0.292CS..Hα-helixtrans-94.7-36.3-171.8178.40000112.4V293 L296 M297 I344V293-V348 HydrophobicContact CG1-CG2 4.46Å; L296-V348 HydrophobicContact CB-CG1 4.1Å; L296-V348 HydrophobicContact CB-CG2 4.02Å; L296-V348 WeakPolarHBondContact O-CG1 3.39Å; M297-V348 HydrophobicContact CG-CG2 4.38Å; M297-V348 HydrophobicContact SD-CB 4.22Å; M297-V348 HydrophobicContact SD-CG1 4.02Å; M297-V348 HydrophobicContact SD-CG2 4.35Å; I344-V348 HydrophobicContact CD1-CG2 3.43Å; I344-V348 VanDerWaalsContact CD1-CG2 3.43Å; I344-V348 HydrophobicContact CG1-CG2 3.69Å; I344-V348 VanDerWaalsContact O-CB 3.32Å; I344-V348 WeakPolarHBondContact O-CB 3.42Å; I344-V348 PolarHBondContact O-N 2.83Å
349F97.2Very high96.1Very high15 Ų1555.7 Ų55.77%0.06630%0.301CS..Hα-helixtrans-117.9-4-172.5-52.3-67.1000113.8T86 L89 R309 T312 Y313 C316 C345 I351T86-F349 HydrophobicContact CG2-CB 3.99Å; T86-F349 HydrophobicContact CG2-CD1 4.06Å; L89-F349 HydrophobicContact CD1-CD1 4.37Å; L89-F349 HydrophobicContact CD1-CE1 3.88Å; R309-F349 HydrophobicContact CG-CE1 3.97Å; R309-F349 HydrophobicContact CG-CZ 4.05Å; R309-F349 WeakPolarHBondContact O-CZ 3.19Å; T312-F349 HydrophobicContact CG2-CE2 3.88Å; Y313-F349 HydrophobicContact CD2-CB 4.37Å; Y313-F349 AromaticContact CD2-CD1 3.65Å; Y313-F349 HydrophobicContact CD2-CD1 3.65Å; Y313-F349 HydrophobicContact CD2-CD2 4.39Å; Y313-F349 AromaticContact CD2-CE1 3.95Å; Y313-F349 HydrophobicContact CD2-CE1 3.95Å; Y313-F349 AromaticContact CD2-CG 3.89Å; Y313-F349 HydrophobicContact CD2-CG 3.89Å; Y313-F349 HydrophobicContact CD2-CZ 4.46Å; Y313-F349 HydrophobicContact CE2-CD1 4.47Å; Y313-F349 HydrophobicContact CG-CE1 4.43Å; C316-F349 HydrophobicContact CB-CD2 4.48Å; C345-F349 CarbonylContact O-C 3.57Å; C345-F349 WeakPolarHBondContact O-CB 3.24Å; C345-F349 PolarHBondContact O-N 3.43Å; C345-F349 VanDerWaalsContact O-N 3.13Å; F349-I351 HydrophobicContact CB-CD1 3.7Å; F349-I351 HydrophobicContact CB-CG1 3.86Å; F349-I351 HydrophobicContact CG-CD1 4.44Å; F349-I351 PolarHBondContact O-N 2.93Å
350G96.9Very high96.4Very high63 Ų6350 Ų5065%0.64928%0.275SS*.  trans66.915.7-17400000113.4C345 T346C345-G350 PolarHBondContact O-N 3.45Å; T346-G350 VanDerWaalsContact O-CA 3.27Å; T346-G350 WeakPolarHBondContact O-CA 3.27Å; T346-G350 PolarHBondContact O-N 2.97Å; T346-G350 VanDerWaalsContact O-N 3.08Å
351I97.6Very high96.7Very high18 Ų1852.1 Ų52.19%0.09229%0.292CS..  trans-85119.7-179.6-63.9168.3000108.7Y313 C316 T317 C345 T346 F349 Q353 L356Y313-I351 HydrophobicContact CD2-CD1 4.29Å; Y313-I351 HydrophobicContact CE2-CD1 4.05Å; C316-I351 HydrophobicContact CB-CD1 3.93Å; T317-I351 HydrophobicContact CG2-CD1 3.54Å; C345-I351 CarbonylContact C-O 3.4Å; C345-I351 HydrophobicContact CB-CB 4.28Å; C345-I351 PolarHBondContact O-N 3.47Å; T346-I351 WeakPolarHBondContact CA-O 3.48Å; T346-I351 WeakPolarHBondContact CB-O 3.46Å; T346-I351 PolarHBondContact N-O 3.1Å; T346-I351 VanDerWaalsContact N-O 3.11Å; T346-I351 PolarHBondContact OG1-O 3.28Å; F349-I351 HydrophobicContact CB-CD1 3.7Å; F349-I351 HydrophobicContact CB-CG1 3.86Å; F349-I351 HydrophobicContact CG-CD1 4.44Å; F349-I351 PolarHBondContact O-N 2.93Å; I351-Q353 PolarHBondContact O-N 2.96Å; I351-L356 HydrophobicContact CG2-CD2 4.08Å
352S96.4Very high97Very high56 Ų5655.9 Ų55.939%0.39231%0.308SS..  trans-66132.1177.6176.60000111.4H354 S355S352-H354 PolarHBondContact O-N 2.78Å; S352-H354 PolarHBondContact OG-N 3.36Å; S352-S355 WeakPolarHBondContact O-CB 3.12Å; S352-S355 PolarHBondContact O-N 2.93Å; S352-S355 PolarHBondContact O-OG 2.9Å
353Q95.3Very high97.1Very high59 Ų5955.6 Ų55.628%0.27631%0.307SS..G310 helixtrans-54.2-35.3173.8-64.9-176.74.600112.3T342 K343 I351 S355 L356T342-Q353 VanDerWaalsContact C-NE2 3.34Å; T342-Q353 WeakPolarHBondContact O-CG 3.47Å; T342-Q353 PolarHBondContact O-NE2 3.44Å; K343-Q353 VanDerWaalsContact N-NE2 3.17Å; I351-Q353 PolarHBondContact O-N 2.96Å; Q353-S355 PolarHBondContact O-N 3.19Å; Q353-S355 VanDerWaalsContact O-N 3.15Å; Q353-L356 HydrophobicContact CB-CD1 4.49Å; Q353-L356 WeakPolarHBondContact O-CB 3.3Å; Q353-L356 WeakPolarHBondContact O-CG 3.44Å; Q353-L356 PolarHBondContact O-N 2.92Å; Q353-L356 VanDerWaalsContact O-N 3.12Å
354H95.6Very high97.2Very high174 Ų17453.4 Ų53.481%0.80630%0.299SS*.G310 helixtrans-63.7-20.6178.3-62-62.2000113.3S352S352-H354 PolarHBondContact O-N 2.78Å; S352-H354 PolarHBondContact OG-N 3.36Å
355S97.3Very high97.3Very high29 Ų2957.4 Ų57.420%0.20333%0.329CS..G310 helixtrans-83.7-21.2177.675.50000113.5S352 Q353 S358 R359S352-S355 WeakPolarHBondContact O-CB 3.12Å; S352-S355 PolarHBondContact O-N 2.93Å; S352-S355 PolarHBondContact O-OG 2.9Å; Q353-S355 PolarHBondContact O-N 3.19Å; Q353-S355 VanDerWaalsContact O-N 3.15Å; S355-S358 PolarHBondContact O-N 3.42Å; S355-S358 PolarHBondContact O-OG 3.35Å; S355-R359 WeakPolarHBondContact O-CG 3.47Å; S355-R359 PolarHBondContact O-N 3.27Å; S355-R359 PolarHBondContact OG-NE 3.49Å; S355-R359 VanDerWaalsContact OG-NE 3.16Å
356L98Very high97.3Very high2 Ų261.1 Ų61.11%0.0134%0.343CS..Hα-helixtrans-57.2-46.7-172.8-55.7176000113.1L157 C316 Y322 T342 I351 Q353 S358 R359 I360L157-L356 HydrophobicContact CD1-CB 3.85Å; L157-L356 HydrophobicContact CD1-CD1 4.03Å; C316-L356 HydrophobicContact CB-CD2 4.42Å; C316-L356 WeakPolarHBondContact O-CD2 3.37Å; Y322-L356 HydrophobicContact CE2-CD1 4.35Å; T342-L356 HydrophobicContact CG2-CD1 3.67Å; I351-L356 HydrophobicContact CG2-CD2 4.08Å; Q353-L356 HydrophobicContact CB-CD1 4.49Å; Q353-L356 WeakPolarHBondContact O-CB 3.3Å; Q353-L356 WeakPolarHBondContact O-CG 3.44Å; Q353-L356 PolarHBondContact O-N 2.92Å; Q353-L356 VanDerWaalsContact O-N 3.12Å; L356-S358 VanDerWaalsContact C-N 3.3Å; L356-S358 PolarHBondContact O-N 3.11Å; L356-R359 PolarHBondContact O-N 3.32Å; L356-I360 HydrophobicContact CB-CD1 4.47Å; L356-I360 WeakPolarHBondContact O-CD1 3.35Å; L356-I360 WeakPolarHBondContact O-CG1 3.34Å; L356-I360 PolarHBondContact O-N 2.95Å
357P98.1Very high97.2Very high70 Ų7058.6 Ų58.646%0.45533%0.326SS..Hα-helixtrans-57.8-41.6-179.9-24.433.8000113.2L157 I360 A361L157-P357 HydrophobicContact CD2-CG 4.05Å; P357-I360 PolarHBondContact O-N 2.6Å; P357-A361 VanDerWaalsContact O-CB 3.28Å; P357-A361 WeakPolarHBondContact O-CB 3.48Å; P357-A361 PolarHBondContact O-N 3.31Å
358S98.1Very high97.1Very high77 Ų7753.4 Ų53.454%0.53831%0.314SS..Hα-helixtrans-68.1-35.9-179.267.90000112.9S355 L356 F362S355-S358 PolarHBondContact O-N 3.42Å; S355-S358 PolarHBondContact O-OG 3.35Å; L356-S358 VanDerWaalsContact C-N 3.3Å; L356-S358 PolarHBondContact O-N 3.11Å; S358-F362 PolarHBondContact O-N 3.39Å
359R97.7Very high96.9Very high99 Ų9953.3 Ų53.337%0.37431%0.314SS..Hα-helixtrans-68-45177.4-70.1173178.6-77.70.5111.4T317 S355 L356 F362 T363T317-R359 WeakPolarHBondContact O-CB 3.35Å; S355-R359 WeakPolarHBondContact O-CG 3.47Å; S355-R359 PolarHBondContact O-N 3.27Å; S355-R359 PolarHBondContact OG-NE 3.49Å; S355-R359 VanDerWaalsContact OG-NE 3.16Å; L356-R359 PolarHBondContact O-N 3.32Å; R359-F362 WeakPolarHBondContact O-CB 3.27Å; R359-F362 PolarHBondContact O-N 2.76Å; R359-T363 PolarHBondContact O-N 2.75Å; R359-T363 PolarHBondContact O-OG1 3.3Å
360I98.3Very high96.2Very high11 Ų1156 Ų566%0.05633%0.329CS..Hα-helixtrans-66.2-41177.3-67.9164.6000110.9A155 L157 L356 P357 F362 T363 N364A155-I360 HydrophobicContact CB-CG2 3.86Å; L157-I360 HydrophobicContact CB-CD1 3.55Å; L157-I360 HydrophobicContact CD1-CD1 3.56Å; L157-I360 HydrophobicContact CG-CD1 4.12Å; L356-I360 HydrophobicContact CB-CD1 4.47Å; L356-I360 WeakPolarHBondContact O-CD1 3.35Å; L356-I360 WeakPolarHBondContact O-CG1 3.34Å; L356-I360 PolarHBondContact O-N 2.95Å; P357-I360 PolarHBondContact O-N 2.6Å; I360-F362 VanDerWaalsContact C-N 3.29Å; I360-F362 PolarHBondContact O-N 3.07Å; I360-T363 WeakPolarHBondContact O-CB 3.41Å; I360-T363 PolarHBondContact O-N 3.22Å; I360-N364 PolarHBondContact O-N 3.45Å; I360-N364 PolarHBondContact O-ND2 3.48Å
361A98.3Very high95.7Very high55 Ų5558 Ų5846%0.45533%0.325SS..Hα-helixtrans-60.6-39.2173.200000111.9P357 N364 S365P357-A361 VanDerWaalsContact O-CB 3.28Å; P357-A361 WeakPolarHBondContact O-CB 3.48Å; P357-A361 PolarHBondContact O-N 3.31Å; A361-N364 PolarHBondContact O-N 3.22Å; A361-S365 WeakPolarHBondContact O-CB 3.41Å; A361-S365 PolarHBondContact O-N 3.1Å
362F98.1Very high95.1Very high114 Ų11457.5 Ų57.550%0.532%0.323SS..Hα-helixtrans-62.1-46.5174172.7-101.9000112S358 R359 I360 N364 S365 Y366S358-F362 PolarHBondContact O-N 3.39Å; R359-F362 WeakPolarHBondContact O-CB 3.27Å; R359-F362 PolarHBondContact O-N 2.76Å; I360-F362 VanDerWaalsContact C-N 3.29Å; I360-F362 PolarHBondContact O-N 3.07Å; F362-N364 VanDerWaalsContact C-N 3.34Å; F362-N364 PolarHBondContact O-N 2.83Å; F362-S365 PolarHBondContact O-N 2.81Å; F362-Y366 HydrophobicContact CZ-CD2 4.23Å; F362-Y366 VanDerWaalsContact O-CB 3.27Å; F362-Y366 WeakPolarHBondContact O-CB 3.36Å; F362-Y366 PolarHBondContact O-N 2.83Å
363T98.3Very high94.5Very high1 Ų163 Ų631%0.00635%0.348CS..Hα-helixtrans-55.1-49.5176.2-56.80000111.5A155 E318 F319 R359 I360 S365 Y366 Y367A155-T363 HydrophobicContact CB-CG2 3.73Å; E318-T363 WeakPolarHBondContact CA-OG1 3.44Å; E318-T363 VanDerWaalsContact O-CB 3.29Å; E318-T363 WeakPolarHBondContact O-CB 3.46Å; E318-T363 PolarHBondContact O-OG1 3.11Å; F319-T363 HydrophobicContact CD1-CG2 4.02Å; F319-T363 HydrophobicContact CE1-CG2 4.03Å; R359-T363 PolarHBondContact O-N 2.75Å; R359-T363 PolarHBondContact O-OG1 3.3Å; I360-T363 WeakPolarHBondContact O-CB 3.41Å; I360-T363 PolarHBondContact O-N 3.22Å; T363-S365 PolarHBondContact O-N 3.39Å; T363-Y366 PolarHBondContact O-N 2.68Å; T363-Y367 HydrophobicContact CG2-CD2 3.76Å; T363-Y367 HydrophobicContact CG2-CE2 4.02Å; T363-Y367 VanDerWaalsContact O-CD2 3.27Å; T363-Y367 WeakPolarHBondContact O-CD2 3.44Å; T363-Y367 PolarHBondContact O-N 2.88Å
364N98.1Very high93.9Very high39 Ų3961 Ų6121%0.20934%0.34CS..Hα-helixtrans-64.5-41.1177.8-74.1-34000112.7A155 I360 A361 F362 Y366 G368 G369A155-N364 PolarHBondContact N-OD1 3.14Å; A155-N364 PolarHBondContact O-ND2 3.49Å; A155-N364 PolarHBondContact O-OD1 3.07Å; I360-N364 PolarHBondContact O-N 3.45Å; I360-N364 PolarHBondContact O-ND2 3.48Å; A361-N364 PolarHBondContact O-N 3.22Å; F362-N364 VanDerWaalsContact C-N 3.34Å; F362-N364 PolarHBondContact O-N 2.83Å; N364-Y366 VanDerWaalsContact C-N 3.27Å; N364-Y366 PolarHBondContact O-N 3.16Å; N364-G368 CarbonylContact O-C 3.55Å; N364-G368 VanDerWaalsContact O-CA 3.3Å; N364-G368 WeakPolarHBondContact O-CA 3.5Å; N364-G368 PolarHBondContact O-N 2.93Å; N364-G369 PolarHBondContact O-N 2.69Å
365S97Very high93.5Very high104 Ų10456.5 Ų56.573%0.72732%0.316SS*.Hα-helixtrans-65-34.1176-177.10000112.1A361 F362 T363A361-S365 WeakPolarHBondContact O-CB 3.41Å; A361-S365 PolarHBondContact O-N 3.1Å; F362-S365 PolarHBondContact O-N 2.81Å; T363-S365 PolarHBondContact O-N 3.39Å
366Y96.8Very high93.3Very high78 Ų7856.2 Ų56.231%0.30631%0.311SS..Hα-helixtrans-76-37.9-177.9-172.3-98.7000111.6Q95 K138 F362 T363 N364Q95-Y366 HydrophobicContact CG-CD1 4.17Å; Q95-Y366 HydrophobicContact CG-CE1 3.67Å; K138-Y366 HydrophobicContact CD-CE1 4.37Å; K138-Y366 VanDerWaalsContact CE-O 3.22Å; K138-Y366 WeakPolarHBondContact CE-O 3.44Å; K138-Y366 PolarHBondContact NZ-O 2.8Å; F362-Y366 HydrophobicContact CZ-CD2 4.23Å; F362-Y366 VanDerWaalsContact O-CB 3.27Å; F362-Y366 WeakPolarHBondContact O-CB 3.36Å; F362-Y366 PolarHBondContact O-N 2.83Å; T363-Y366 PolarHBondContact O-N 2.68Å; N364-Y366 VanDerWaalsContact C-N 3.27Å; N364-Y366 PolarHBondContact O-N 3.16Å
367Y96.1Very high93.2Very high15 Ų1556.1 Ų56.16%0.05931%0.31CS..Hα-helixtrans-103-17.8-175.3-63.9-59.4000115.6S94 Q95 L98 W134 T363S94-Y367 WeakPolarHBondContact CB-OH 3.46Å; S94-Y367 WeakPolarHBondContact OG-CE2 3.49Å; S94-Y367 PolarHBondContact OG-OH 3Å; Q95-Y367 PolarHBondContact N-OH 3.47Å; L98-Y367 HydrophobicContact CD1-CE1 3.64Å; W134-Y367 HydrophobicContact CB-CD1 3.82Å; W134-Y367 HydrophobicContact CB-CE1 3.83Å; W134-Y367 AromaticContact CD1-CD1 3.62Å; W134-Y367 AromaticContact CD1-CG 3.8Å; W134-Y367 AromaticContact CD2-CD1 3.66Å; W134-Y367 HydrophobicContact CD2-CD1 3.66Å; W134-Y367 HydrophobicContact CD2-CD2 4Å; W134-Y367 AromaticContact CD2-CE1 3.8Å; W134-Y367 HydrophobicContact CD2-CE1 3.8Å; W134-Y367 HydrophobicContact CD2-CE2 4.13Å; W134-Y367 AromaticContact CD2-CG 3.78Å; W134-Y367 HydrophobicContact CD2-CG 3.78Å; W134-Y367 AromaticContact CE2-CD2 3.79Å; W134-Y367 AromaticContact CE2-CG 3.63Å; W134-Y367 HydrophobicContact CE3-CD1 4.31Å; W134-Y367 HydrophobicContact CE3-CD2 4.29Å; W134-Y367 HydrophobicContact CE3-CE1 4Å; W134-Y367 AromaticContact CE3-CE2 3.98Å; W134-Y367 HydrophobicContact CE3-CE2 3.98Å; W134-Y367 HydrophobicContact CE3-CG 4.45Å; W134-Y367 AromaticContact CE3-CZ 3.83Å; W134-Y367 AromaticContact CG-CD1 3.4Å; W134-Y367 HydrophobicContact CG-CD1 3.4Å; W134-Y367 VanDerWaalsContact CG-CD1 3.4Å; W134-Y367 AromaticContact CG-CE1 3.74Å; W134-Y367 HydrophobicContact CG-CE1 3.74Å; W134-Y367 AromaticContact CG-CG 3.88Å; W134-Y367 HydrophobicContact CG-CG 3.88Å; W134-Y367 HydrophobicContact CH2-CD2 4.21Å; W134-Y367 HydrophobicContact CH2-CE2 4.23Å; W134-Y367 AromaticContact CZ2-CD2 3.89Å; W134-Y367 HydrophobicContact CZ2-CD2 3.89Å; W134-Y367 HydrophobicContact CZ2-CE2 4.35Å; W134-Y367 HydrophobicContact CZ2-CG 4.19Å; W134-Y367 HydrophobicContact CZ3-CD2 4.4Å; W134-Y367 HydrophobicContact CZ3-CE2 4.04Å; W134-Y367 AromaticContact NE1-CD1 3.96Å; W134-Y367 AromaticContact NE1-CG 3.65Å; T363-Y367 HydrophobicContact CG2-CD2 3.76Å; T363-Y367 HydrophobicContact CG2-CE2 4.02Å; T363-Y367 VanDerWaalsContact O-CD2 3.27Å; T363-Y367 WeakPolarHBondContact O-CD2 3.44Å; T363-Y367 PolarHBondContact O-N 2.88Å
368G93.2Very high93.1Very high36 Ų3652.8 Ų52.837%0.37129%0.289SS..  trans96-0.9-179.700000115.3N364 N371N364-G368 CarbonylContact O-C 3.55Å; N364-G368 VanDerWaalsContact O-CA 3.3Å; N364-G368 WeakPolarHBondContact O-CA 3.5Å; N364-G368 PolarHBondContact O-N 2.93Å; G368-N371 CarbonylContact O-C 3.58Å; G368-N371 PolarHBondContact O-N 3.29Å
369G91.7Very high93.1Very high5 Ų549.1 Ų49.15%0.05226%0.263CS..THydrogen-bonded Turntrans60.3-137.1179.300000113V153 N364 N371 P372V153-G369 VanDerWaalsContact CG2-O 3.32Å; V153-G369 WeakPolarHBondContact CG2-O 3.2Å; N364-G369 PolarHBondContact O-N 2.69Å; G369-N371 VanDerWaalsContact C-N 3.3Å; G369-P372 WeakPolarHBondContact O-CD 3.27Å
370D83.9Confident93.1Very high70 Ų7044.4 Ų44.437%0.37425%0.245SC..THydrogen-bonded Turntrans-84.42.7177.956.3-17.6000114.1K154K154-D370 HydrophobicContact CB-CB 4.13Å; K154-D370 HydrophobicContact CD-CB 4.04Å; K154-D370 WeakPolarHBondContact CE-OD2 3.44Å; K154-D370 HydrophobicContact CG-CB 4.47Å; K154-D370 IonicContact NZ-OD1 3.51Å; K154-D370 IonicContact NZ-OD2 2.69Å; K154-D370 PolarHBondContact NZ-OD2 2.76Å
371N86.9Confident93Very high105 Ų10544 Ų4456%0.56124%0.243SC*.SBendtrans-126.360.5168.3-171.232000111.4G368 G369 S396G368-N371 CarbonylContact O-C 3.58Å; G368-N371 PolarHBondContact O-N 3.29Å; G369-N371 VanDerWaalsContact C-N 3.3Å; N371-S396 VanDerWaalsContact OD1-CB 3.27Å; N371-S396 WeakPolarHBondContact OD1-CB 3.24Å; N371-S396 PolarHBondContact OD1-OG 3.49Å
372P84.9Confident93Very high8 Ų841.5 Ų41.55%0.05222%0.222CC..  trans-74.5136.8-176.532.8-34.7000110.6G369 T374 Y379 V392G369-P372 WeakPolarHBondContact O-CD 3.27Å; P372-T374 HydrophobicContact CB-CG2 3.85Å; P372-T374 HydrophobicContact CG-CG2 4.41Å; P372-T374 PolarHBondContact O-N 3.08Å; P372-Y379 HydrophobicContact CG-CE2 4.26Å; P372-Y379 VanDerWaalsContact CG-OH 3.25Å; P372-Y379 WeakPolarHBondContact CG-OH 3.49Å; P372-V392 HydrophobicContact CG-CG2 3.69Å
373N83.3Confident92.8Very high173 Ų17336.5 Ų36.593%0.92520%0.204SC*.  trans-78.366.2170.2-171.520.5000110.2
374T82.9Confident92.7Very high16 Ų1636.6 Ų36.610%0.09820%0.204CC..  trans-108.5141.7-176.149.10000112.2P372 V377 Y379P372-T374 HydrophobicContact CB-CG2 3.85Å; P372-T374 HydrophobicContact CG-CG2 4.41Å; P372-T374 PolarHBondContact O-N 3.08Å; T374-V377 HydrophobicContact CG2-CG2 4.24Å; T374-Y379 PolarHBondContact OG1-OH 2.98Å
375Y87.5Confident92.7Very high80 Ų8034.7 Ų34.731%0.31419%0.194SC..SBendtrans-117.4136177179.1-131.9000111.6R136 V377 E399R136-Y375 PolarHBondContact NE-O 3Å; Y375-V377 VanDerWaalsContact C-N 3.33Å; Y375-E399 HydrophobicContact CD2-CB 3.54Å; Y375-E399 HydrophobicContact CD2-CG 4.16Å; Y375-E399 WeakPolarHBondContact CD2-OE2 3.29Å; Y375-E399 HydrophobicContact CE2-CB 3.53Å; Y375-E399 HydrophobicContact CE2-CG 3.71Å; Y375-E399 WeakPolarHBondContact CE2-OE1 3.42Å; Y375-E399 WeakPolarHBondContact CE2-OE2 3.48Å; Y375-E399 VanDerWaalsContact CZ-OE1 3.24Å; Y375-E399 PolarHBondContact OH-OE1 3.3Å
376R93Very high92.7Very high22 Ų2229.8 Ų29.88%0.08316%0.159CC..SBendtrans59.442.5-176.4-57.1172.5-177.3160.42.7112.5Y144 G145 A146 W439 E446Y144-R376 VanDerWaalsContact CZ-CZ 3.44Å; Y144-R376 WeakPolarHBondContact O-CB 3.43Å; Y144-R376 VanDerWaalsContact O-CD 3.23Å; Y144-R376 WeakPolarHBondContact O-CD 3.21Å; Y144-R376 PolarHBondContact OH-NH1 3.16Å; Y144-R376 VanDerWaalsContact OH-NH1 3.15Å; Y144-R376 PolarHBondContact OH-NH2 3.29Å; G145-R376 CarbonylContact C-O 3.59Å; G145-R376 WeakPolarHBondContact CA-O 3.37Å; A146-R376 PolarHBondContact N-O 3.1Å; R376-W439 HydrophobicContact CB-CZ2 4.17Å; R376-W439 WeakPolarHBondContact O-CH2 3.4Å; R376-E446 IonicContact CZ-OE1 3.14Å; R376-E446 IonicContact CZ-OE2 2.71Å; R376-E446 IonicContact NH1-OE1 3.55Å; R376-E446 IonicContact NH1-OE2 3.38Å; R376-E446 PolarHBondContact NH1-OE2 3.07Å; R376-E446 IonicContact NH2-OE1 2.78Å; R376-E446 PolarHBondContact NH2-OE1 3.44Å; R376-E446 IonicContact NH2-OE2 3.32Å
377V95.4Very high92.8Very high0 Ų026.9 Ų26.90%015%0.148CC..EExtended strand (participates in β ladder)trans-114.2127.8168.6-175.30000107.7A133 R136 A146 A148 T374 Y375 Y379 Q401A133-V377 HydrophobicContact CB-CG1 3.75Å; R136-V377 HydrophobicContact CB-CG2 3.95Å; R136-V377 HydrophobicContact CG-CG2 3.58Å; A146-V377 HydrophobicContact CB-CG1 4.34Å; A146-V377 HydrophobicContact CB-CG2 4.33Å; A146-V377 WeakPolarHBondContact O-CA 3.45Å; A148-V377 HydrophobicContact CB-CG1 4.23Å; T374-V377 HydrophobicContact CG2-CG2 4.24Å; Y375-V377 VanDerWaalsContact C-N 3.33Å; V377-Y379 HydrophobicContact CB-CE2 3.89Å; V377-Y379 HydrophobicContact CG1-CD1 4.23Å; V377-Y379 HydrophobicContact CG1-CD2 4.05Å; V377-Y379 HydrophobicContact CG1-CE1 3.77Å; V377-Y379 HydrophobicContact CG1-CE2 3.57Å; V377-Y379 HydrophobicContact CG1-CG 4.36Å; V377-Y379 VanDerWaalsContact CG1-CZ 3.41Å; V377-Q401 PolarHBondContact O-N 3.13Å
378L96.3Very high92.8Very high0 Ų027.5 Ų27.50%015%0.151CC..EExtended strand (participates in β ladder)trans-103108.1175.3-174.370.4000107.9A146 V147 A148 V380 Q401 V403 I432 H435 W439A146-L378 PolarHBondContact O-N 3.15Å; V147-L378 HydrophobicContact CG2-CD2 4.43Å; A148-L378 PolarHBondContact N-O 3.06Å; L378-V380 HydrophobicContact CD2-CG2 4.2Å; L378-V380 HydrophobicContact CG-CG2 4.1Å; L378-Q401 CarbonylContact C-O 3.28Å; L378-Q401 VanDerWaalsContact CA-O 3.3Å; L378-Q401 WeakPolarHBondContact CA-O 3.49Å; L378-Q401 HydrophobicContact CD1-CB 3.63Å; L378-Q401 WeakPolarHBondContact CD1-O 3.39Å; L378-V403 HydrophobicContact CD1-CG2 3.7Å; L378-V403 HydrophobicContact CD2-CG2 4.36Å; L378-V403 HydrophobicContact CG-CG2 4.26Å; L378-I432 HydrophobicContact CD2-CB 4.09Å; L378-I432 HydrophobicContact CD2-CG1 3.83Å; L378-I432 HydrophobicContact CD2-CG2 4.02Å; L378-H435 HydrophobicContact CD1-CB 4.37Å; L378-H435 HydrophobicContact CD2-CB 3.91Å; L378-W439 HydrophobicContact CB-CH2 3.59Å; L378-W439 HydrophobicContact CB-CZ2 4.27Å; L378-W439 HydrophobicContact CB-CZ3 4.42Å
379Y96.6Very high92.9Very high1 Ų129.9 Ų29.90%0.00415%0.152CC..EExtended strand (participates in β ladder)trans-89.9111.3176.2-63.2-81.7000109A133 A148 V153 P372 T374 V377 V392 Q401 T402 V403A133-Y379 HydrophobicContact CB-CE1 3.72Å; A148-Y379 HydrophobicContact CB-CD1 4.12Å; A148-Y379 HydrophobicContact CB-CE1 4.39Å; V153-Y379 HydrophobicContact CG1-CE1 3.95Å; V153-Y379 HydrophobicContact CG2-CE1 4.41Å; P372-Y379 HydrophobicContact CG-CE2 4.26Å; P372-Y379 VanDerWaalsContact CG-OH 3.25Å; P372-Y379 WeakPolarHBondContact CG-OH 3.49Å; T374-Y379 PolarHBondContact OG1-OH 2.98Å; V377-Y379 HydrophobicContact CB-CE2 3.89Å; V377-Y379 HydrophobicContact CG1-CD1 4.23Å; V377-Y379 HydrophobicContact CG1-CD2 4.05Å; V377-Y379 HydrophobicContact CG1-CE1 3.77Å; V377-Y379 HydrophobicContact CG1-CE2 3.57Å; V377-Y379 HydrophobicContact CG1-CG 4.36Å; V377-Y379 VanDerWaalsContact CG1-CZ 3.41Å; Y379-V392 HydrophobicContact CD1-CB 4.09Å; Y379-V392 HydrophobicContact CD1-CG2 4.05Å; Y379-V392 HydrophobicContact CD2-CB 3.71Å; Y379-V392 HydrophobicContact CD2-CG1 4.08Å; Y379-V392 HydrophobicContact CD2-CG2 3.98Å; Y379-V392 HydrophobicContact CE1-CB 4.47Å; Y379-V392 HydrophobicContact CE1-CG2 3.94Å; Y379-V392 HydrophobicContact CE2-CB 4.11Å; Y379-V392 HydrophobicContact CE2-CG1 4.44Å; Y379-V392 HydrophobicContact CE2-CG2 3.86Å; Y379-V392 HydrophobicContact CG-CB 3.7Å; Y379-V392 HydrophobicContact CG-CG1 4.49Å; Y379-V392 HydrophobicContact CG-CG2 4.07Å; Y379-Q401 PolarHBondContact N-O 3.2Å; Y379-T402 CarbonylContact O-C 3.54Å; Y379-T402 VanDerWaalsContact O-CA 3.32Å; Y379-T402 WeakPolarHBondContact O-CA 3.47Å; Y379-V403 PolarHBondContact O-N 2.96Å
380V97.6Very high93.2Very high0 Ų029.8 Ų29.80%015%0.151CC..EExtended strand (participates in β ladder)trans-101.8131-179.6-172.10000108.4V147 A148 S150 L378 V403 I405 D413 I432V147-V380 HydrophobicContact CG1-CG2 4.13Å; A148-V380 PolarHBondContact O-N 3.43Å; S150-V380 WeakPolarHBondContact CA-O 3.44Å; S150-V380 PolarHBondContact N-O 2.71Å; L378-V380 HydrophobicContact CD2-CG2 4.2Å; L378-V380 HydrophobicContact CG-CG2 4.1Å; V380-V403 CarbonylContact C-O 3.6Å; V380-V403 WeakPolarHBondContact CA-O 3.5Å; V380-V403 HydrophobicContact CG1-CB 4.27Å; V380-V403 HydrophobicContact CG1-CG1 4.24Å; V380-V403 HydrophobicContact CG2-CB 4.3Å; V380-I405 HydrophobicContact CG1-CD1 3.99Å; V380-I405 HydrophobicContact CG1-CG1 4.46Å; V380-D413 HydrophobicContact CG1-CB 4.23Å; V380-I432 HydrophobicContact CB-CD1 4.43Å; V380-I432 HydrophobicContact CG1-CD1 3.89Å; V380-I432 HydrophobicContact CG2-CD1 3.73Å; V380-I432 HydrophobicContact CG2-CG1 3.83Å
381N97.7Very high93.8Very high2 Ų226.7 Ų26.71%0.01113%0.134CC..EExtended strand (participates in β ladder)trans-135.2134.9-178.4-69-71.5000112K388 S391 V392 V393 V403 F404 I405N381-K388 HydrophobicContact CB-CB 4.26Å; N381-S391 VanDerWaalsContact CG-OG 3.31Å; N381-S391 PolarHBondContact ND2-OG 3.08Å; N381-S391 VanDerWaalsContact ND2-OG 3.1Å; N381-S391 WeakPolarHBondContact OD1-CB 3.43Å; N381-S391 PolarHBondContact OD1-OG 3.44Å; N381-V392 PolarHBondContact ND2-O 3.49Å; N381-V393 HydrophobicContact CB-CG1 4.32Å; N381-V403 PolarHBondContact N-O 2.44Å; N381-F404 HydrophobicContact CB-CD2 4.12Å; N381-I405 PolarHBondContact O-N 3.49Å
382G96.8Very high94.1Very high2 Ų221.8 Ų21.82%0.02111%0.108CC..EExtended strand (participates in β ladder)trans-79.4140.4170.300000111.6D385 I405 T408G382-D385 WeakPolarHBondContact O-CB 3.5Å; G382-D385 PolarHBondContact O-N 3.33Å; G382-I405 CarbonylContact C-O 3.28Å; G382-T408 CarbonylContact C-O 3.48Å; G382-T408 VanDerWaalsContact C-O 3.28Å; G382-T408 WeakPolarHBondContact CA-O 3.39Å
383G95.2Very high94.2Very high10 Ų1024.3 Ų24.310%0.10312%0.123CC..SBendtrans-77.4-21.9-177.600000114.4K388 F404 I405 K406 T408G383-K388 PolarHBondContact O-NZ 3.03Å; G383-F404 VanDerWaalsContact CA-CZ 3.47Å; G383-I405 PolarHBondContact N-O 2.86Å; G383-K406 VanDerWaalsContact CA-O 3.27Å; G383-K406 WeakPolarHBondContact CA-O 3.38Å; G383-T408 PolarHBondContact N-O 2.97Å; G383-T408 VanDerWaalsContact N-O 3.16Å
384V96.1Very high93.9Very high2 Ų223.5 Ų23.51%0.01211%0.114CC..SBendtrans-99.8-3.7170.6-60.90000113.2V175 V235 P386 T408 A409V175-V384 HydrophobicContact CG1-CG1 4.1Å; V175-V384 HydrophobicContact CG2-CG1 4.09Å; V235-V384 WeakPolarHBondContact CG1-O 3.36Å; V384-P386 WeakPolarHBondContact O-CD 3.49Å; V384-T408 WeakPolarHBondContact CG2-O 3.34Å; V384-T408 PolarHBondContact N-O 3.46Å; V384-A409 HydrophobicContact CG2-CB 4.44Å
385D97.7Very high93.1Very high0 Ų027.4 Ų27.40%013%0.134CC..  trans-69.2120.4174.8176.817000111.1S150 G382 W387 K388 H410S150-D385 VanDerWaalsContact CB-OD2 3.25Å; S150-D385 WeakPolarHBondContact CB-OD2 3.42Å; S150-D385 PolarHBondContact OG-OD2 3.33Å; G382-D385 WeakPolarHBondContact O-CB 3.5Å; G382-D385 PolarHBondContact O-N 3.33Å; D385-W387 VanDerWaalsContact C-N 3.26Å; D385-W387 PolarHBondContact O-N 2.98Å; D385-W387 WeakPolarHBondContact OD1-CB 3.39Å; D385-W387 PolarHBondContact OD1-N 3.5Å; D385-K388 WeakPolarHBondContact O-CD 3.39Å; D385-K388 VanDerWaalsContact O-CG 3.23Å; D385-K388 WeakPolarHBondContact O-CG 3.43Å; D385-K388 PolarHBondContact O-N 3.35Å; D385-H410 HydrophobicContact CB-CB 4.36Å; D385-H410 IonicContact OD1-CG 3.42Å; D385-H410 IonicContact OD1-ND1 3.37Å; D385-H410 PolarHBondContact OD1-ND1 2.99Å; D385-H410 IonicContact OD2-CE1 3.1Å; D385-H410 IonicContact OD2-CG 2.66Å; D385-H410 IonicContact OD2-ND1 2.59Å; D385-H410 PolarHBondContact OD2-ND1 2.69Å
386P97.5Very high91.5Very high0 Ų026.8 Ų26.80%014%0.142CC..G310 helixtrans-62.7-28.9175.8-2436.9000114.4F159 Y162 V165 V166 V235 V384 K388F159-P386 WeakPolarHBondContact CZ-O 3.45Å; Y162-P386 HydrophobicContact CD1-CB 3.9Å; Y162-P386 HydrophobicContact CD1-CG 4.37Å; Y162-P386 HydrophobicContact CD2-CB 3.42Å; Y162-P386 VanDerWaalsContact CD2-CB 3.42Å; Y162-P386 HydrophobicContact CD2-CG 4.4Å; Y162-P386 HydrophobicContact CE1-CB 3.88Å; Y162-P386 HydrophobicContact CE1-CG 3.93Å; Y162-P386 HydrophobicContact CE2-CB 3.47Å; Y162-P386 VanDerWaalsContact CE2-CB 3.47Å; Y162-P386 HydrophobicContact CE2-CG 4.03Å; Y162-P386 HydrophobicContact CG-CB 3.64Å; V165-P386 HydrophobicContact CB-CB 4.22Å; V165-P386 HydrophobicContact CG1-CB 4.36Å; V165-P386 HydrophobicContact CG1-CG 4.44Å; V166-P386 HydrophobicContact CG2-CB 4.23Å; V166-P386 HydrophobicContact CG2-CG 3.48Å; V166-P386 VanDerWaalsContact CG2-CG 3.48Å; V235-P386 HydrophobicContact CG1-CG 4.48Å; V384-P386 WeakPolarHBondContact O-CD 3.49Å; P386-K388 PolarHBondContact O-N 3.14Å
387W98.1Very high89.6Confident17 Ų1728.4 Ų28.46%0.06416%0.156CC..G310 helixtrans-70.5-14.3-176.9-71.2102.1000114.2P152 F159 Y162 F321 D385 E389 L390 H410P152-W387 HydrophobicContact CB-CE3 3.7Å; P152-W387 HydrophobicContact CB-CZ3 4.18Å; P152-W387 HydrophobicContact CG-CE3 3.98Å; P152-W387 HydrophobicContact CG-CZ3 4.33Å; F159-W387 HydrophobicContact CD1-CE3 4.38Å; F159-W387 HydrophobicContact CD1-CZ3 4.07Å; F159-W387 HydrophobicContact CE1-CD2 4.25Å; F159-W387 AromaticContact CE1-CE3 3.63Å; F159-W387 HydrophobicContact CE1-CE3 3.63Å; F159-W387 AromaticContact CE1-CZ3 3.79Å; F159-W387 HydrophobicContact CE1-CZ3 3.79Å; Y162-W387 HydrophobicContact CE2-CD2 4.36Å; Y162-W387 AromaticContact CE2-CE2 3.84Å; Y162-W387 HydrophobicContact CE2-CG 4.48Å; Y162-W387 HydrophobicContact CE2-CZ2 4.27Å; Y162-W387 AromaticContact CE2-NE1 3.6Å; F321-W387 HydrophobicContact CB-CH2 3.76Å; F321-W387 HydrophobicContact CB-CZ3 3.9Å; F321-W387 HydrophobicContact CD1-CZ3 4.11Å; F321-W387 AromaticContact CD2-CH2 3.9Å; F321-W387 HydrophobicContact CD2-CH2 3.9Å; F321-W387 AromaticContact CD2-CZ3 3.74Å; F321-W387 HydrophobicContact CD2-CZ3 3.74Å; F321-W387 HydrophobicContact CE2-CZ3 4.18Å; F321-W387 AromaticContact CG-CH2 3.96Å; F321-W387 HydrophobicContact CG-CH2 3.96Å; F321-W387 AromaticContact CG-CZ3 3.69Å; F321-W387 HydrophobicContact CG-CZ3 3.69Å; D385-W387 VanDerWaalsContact C-N 3.26Å; D385-W387 PolarHBondContact O-N 2.98Å; D385-W387 WeakPolarHBondContact OD1-CB 3.39Å; D385-W387 PolarHBondContact OD1-N 3.5Å; W387-E389 PolarHBondContact O-N 3.34Å; W387-E389 VanDerWaalsContact O-N 3.08Å; W387-L390 HydrophobicContact CE3-CD1 4.15Å; W387-L390 HydrophobicContact CZ3-CD1 4.06Å; W387-L390 PolarHBondContact O-N 3.28Å; W387-H410 AromaticContact CD1-CE1 3.33Å; W387-H410 AromaticContact CD1-ND1 3.44Å; W387-H410 AromaticContact CD1-NE2 3.99Å; W387-H410 AromaticContact CG-CE1 3.63Å; W387-H410 AromaticContact CG-ND1 3.91Å
388K96.4Very high87.4Confident28 Ų2837.9 Ų37.912%0.12220%0.201CC..G310 helixtrans-55.1-28.7178.176.7-172.7177.2-174.80113.1N381 G383 D385 P386 L390 S391 V393 F404N381-K388 HydrophobicContact CB-CB 4.26Å; G383-K388 PolarHBondContact O-NZ 3.03Å; D385-K388 WeakPolarHBondContact O-CD 3.39Å; D385-K388 VanDerWaalsContact O-CG 3.23Å; D385-K388 WeakPolarHBondContact O-CG 3.43Å; D385-K388 PolarHBondContact O-N 3.35Å; P386-K388 PolarHBondContact O-N 3.14Å; K388-L390 PolarHBondContact O-N 2.94Å; K388-S391 WeakPolarHBondContact O-CB 3.32Å; K388-S391 PolarHBondContact O-N 2.89Å; K388-S391 VanDerWaalsContact O-N 3.07Å; K388-V393 HydrophobicContact CB-CG1 4.19Å; K388-V393 VanDerWaalsContact O-CG1 3.32Å; K388-V393 WeakPolarHBondContact O-CG1 3.46Å; K388-F404 HydrophobicContact CD-CE2 4.29Å
389E96.3Very high85.2Confident87 Ų8742.5 Ų42.541%0.40722%0.222SC..G310 helixtrans-66.5-16.9-179.8-62.9-59.713800113.1F159 E161 V165 W387F159-E389 HydrophobicContact CE2-CB 3.79Å; F159-E389 HydrophobicContact CZ-CB 4.12Å; E161-E389 HydrophobicContact CB-CB 4.37Å; E161-E389 HydrophobicContact CB-CG 4.14Å; V165-E389 HydrophobicContact CG2-CG 3.57Å; W387-E389 PolarHBondContact O-N 3.34Å; W387-E389 VanDerWaalsContact O-N 3.08Å
390L97.3Very high83.3Confident2 Ų242.6 Ų42.61%0.0122%0.223CC..G310 helixtrans-108.68.5176-59.3-176.7000112.7P152 V153 K154 K156 F159 F321 W387 K388P152-L390 CarbonylContact C-O 3.5Å; P152-L390 WeakPolarHBondContact CA-O 3.37Å; P152-L390 HydrophobicContact CB-CB 3.83Å; P152-L390 HydrophobicContact CB-CD1 4.48Å; V153-L390 PolarHBondContact N-O 3.29Å; K154-L390 HydrophobicContact CB-CB 4.37Å; K154-L390 HydrophobicContact CB-CD2 4.45Å; K154-L390 WeakPolarHBondContact CB-O 3.4Å; K154-L390 HydrophobicContact CD-CD2 4.26Å; K154-L390 PolarHBondContact N-O 3.44Å; K156-L390 HydrophobicContact CB-CD1 4.45Å; K156-L390 HydrophobicContact CB-CD2 3.79Å; K156-L390 HydrophobicContact CD-CD2 3.86Å; K156-L390 HydrophobicContact CG-CD2 4.47Å; F159-L390 HydrophobicContact CD1-CD1 3.5Å; F159-L390 HydrophobicContact CD1-CG 4.3Å; F159-L390 HydrophobicContact CD2-CD1 4.04Å; F159-L390 HydrophobicContact CD2-CD2 4.16Å; F159-L390 HydrophobicContact CD2-CG 4.11Å; F159-L390 HydrophobicContact CE1-CD1 3.39Å; F159-L390 HydrophobicContact CE1-CG 3.87Å; F159-L390 HydrophobicContact CE2-CD1 3.98Å; F159-L390 HydrophobicContact CE2-CD2 4.06Å; F159-L390 HydrophobicContact CE2-CG 3.7Å; F159-L390 HydrophobicContact CG-CD1 3.83Å; F159-L390 HydrophobicContact CG-CG 4.41Å; F159-L390 HydrophobicContact CZ-CD1 3.67Å; F159-L390 HydrophobicContact CZ-CD2 4.43Å; F159-L390 HydrophobicContact CZ-CG 3.58Å; F321-L390 HydrophobicContact CD1-CD1 3.49Å; F321-L390 VanDerWaalsContact CD1-CD1 3.49Å; F321-L390 HydrophobicContact CE1-CD1 3.48Å; F321-L390 VanDerWaalsContact CE1-CD1 3.48Å; F321-L390 HydrophobicContact CG-CD1 4.46Å; F321-L390 HydrophobicContact CZ-CD1 4.41Å; W387-L390 HydrophobicContact CE3-CD1 4.15Å; W387-L390 HydrophobicContact CZ3-CD1 4.06Å; W387-L390 PolarHBondContact O-N 3.28Å; K388-L390 PolarHBondContact O-N 2.94Å
391S95.8Very high82.4Confident5 Ų544.5 Ų44.54%0.03523%0.232CC..SBendtrans-106.2175.3-179.9-172.90000111.6A151 N381 K388 V393A151-S391 WeakPolarHBondContact O-CA 3.29Å; A151-S391 VanDerWaalsContact O-CB 3.23Å; A151-S391 WeakPolarHBondContact O-CB 3.1Å; A151-S391 PolarHBondContact O-OG 3.44Å; N381-S391 VanDerWaalsContact CG-OG 3.31Å; N381-S391 PolarHBondContact ND2-OG 3.08Å; N381-S391 VanDerWaalsContact ND2-OG 3.1Å; N381-S391 WeakPolarHBondContact OD1-CB 3.43Å; N381-S391 PolarHBondContact OD1-OG 3.44Å; K388-S391 WeakPolarHBondContact O-CB 3.32Å; K388-S391 PolarHBondContact O-N 2.89Å; K388-S391 VanDerWaalsContact O-N 3.07Å; S391-V393 PolarHBondContact O-N 3.16Å
392V93.3Very high82.1Confident2 Ų245.9 Ų45.91%0.01224%0.24CC..  trans-86.4106.9169.2-1740000108.2V153 P372 Y379 N381 Q394 T402V153-V392 HydrophobicContact CG2-CG2 3.9Å; P372-V392 HydrophobicContact CG-CG2 3.69Å; Y379-V392 HydrophobicContact CD1-CB 4.09Å; Y379-V392 HydrophobicContact CD1-CG2 4.05Å; Y379-V392 HydrophobicContact CD2-CB 3.71Å; Y379-V392 HydrophobicContact CD2-CG1 4.08Å; Y379-V392 HydrophobicContact CD2-CG2 3.98Å; Y379-V392 HydrophobicContact CE1-CB 4.47Å; Y379-V392 HydrophobicContact CE1-CG2 3.94Å; Y379-V392 HydrophobicContact CE2-CB 4.11Å; Y379-V392 HydrophobicContact CE2-CG1 4.44Å; Y379-V392 HydrophobicContact CE2-CG2 3.86Å; Y379-V392 HydrophobicContact CG-CB 3.7Å; Y379-V392 HydrophobicContact CG-CG1 4.49Å; Y379-V392 HydrophobicContact CG-CG2 4.07Å; N381-V392 PolarHBondContact ND2-O 3.49Å; V392-Q394 WeakPolarHBondContact CG1-O 3.2Å; V392-T402 HydrophobicContact CG1-CG2 4.09Å; V392-T402 WeakPolarHBondContact O-CG2 3.44Å
393V87.4Confident82Confident61 Ų6146 Ų4637%0.3724%0.241SC..  trans-107.7-7.8-177.4-66.30000114N381 K388 S391N381-V393 HydrophobicContact CB-CG1 4.32Å; K388-V393 HydrophobicContact CB-CG1 4.19Å; K388-V393 VanDerWaalsContact O-CG1 3.32Å; K388-V393 WeakPolarHBondContact O-CG1 3.46Å; S391-V393 PolarHBondContact O-N 3.16Å
394Q77.9Confident82Confident157 Ų15750.5 Ų50.573%0.73426%0.258SS*.SBendtrans-130.4141.1176.5-67.4-179.98.500109.6V392 S396V392-Q394 WeakPolarHBondContact CG1-O 3.2Å; Q394-S396 PolarHBondContact O-N 3.13Å
395D64.8Low81.9Confident97 Ų9750.7 Ų50.752%0.51926%0.259SS..  trans-70.2111.4177-65.2-23.2000109.6T402D395-T402 VanDerWaalsContact OD1-CB 3.31Å; D395-T402 WeakPolarHBondContact OD1-CB 3.34Å; D395-T402 VanDerWaalsContact OD1-CG2 3.28Å; D395-T402 WeakPolarHBondContact OD1-CG2 3.33Å; D395-T402 PolarHBondContact OD1-N 3.21Å; D395-T402 PolarHBondContact OD1-OG1 3.33Å
396S54.4Low81.7Confident68 Ų6858 Ų5848%0.47629%0.291SS..  trans-92-5.8175.863.80000113.5N371 Q394N371-S396 VanDerWaalsContact OD1-CB 3.27Å; N371-S396 WeakPolarHBondContact OD1-CB 3.24Å; N371-S396 PolarHBondContact OD1-OG 3.49Å; Q394-S396 PolarHBondContact O-N 3.13Å
397S52.9Low81.4Confident55 Ų5559.2 Ų59.239%0.38530%0.297SS..SBendtrans-147.3161.9178.472.10000112.2E399 S400S397-E399 PolarHBondContact O-N 2.94Å; S397-E399 VanDerWaalsContact O-N 3.11Å; S397-S400 PolarHBondContact N-OG 3.27Å; S397-S400 PolarHBondContact O-OG 3.42Å; S397-S400 VanDerWaalsContact OG-CB 3.27Å; S397-S400 WeakPolarHBondContact OG-CB 3.32Å; S397-S400 PolarHBondContact OG-N 3.17Å; S397-S400 PolarHBondContact OG-OG 2.93Å
398E49.8Very low81.2Confident199 Ų19958.7 Ų58.793%0.9330%0.295SS*.SBendtrans-62.7-13.8177.7-70.3-173.3159.200114
399E50.6Low81.2Confident97 Ų9757.4 Ų57.445%0.45329%0.29SS..SBendtrans-125.4-11.9-172.7-64.6-171.512400115.4Y375 S397Y375-E399 HydrophobicContact CD2-CB 3.54Å; Y375-E399 HydrophobicContact CD2-CG 4.16Å; Y375-E399 WeakPolarHBondContact CD2-OE2 3.29Å; Y375-E399 HydrophobicContact CE2-CB 3.53Å; Y375-E399 HydrophobicContact CE2-CG 3.71Å; Y375-E399 WeakPolarHBondContact CE2-OE1 3.42Å; Y375-E399 WeakPolarHBondContact CE2-OE2 3.48Å; Y375-E399 VanDerWaalsContact CZ-OE1 3.24Å; Y375-E399 PolarHBondContact OH-OE1 3.3Å; S397-E399 PolarHBondContact O-N 2.94Å; S397-E399 VanDerWaalsContact O-N 3.11Å
400S55.7Low81.2Confident3 Ų353.6 Ų53.62%0.02127%0.273CS..  trans-76.1124.8163.658.50000108.3S397S397-S400 PolarHBondContact N-OG 3.27Å; S397-S400 PolarHBondContact O-OG 3.42Å; S397-S400 VanDerWaalsContact OG-CB 3.27Å; S397-S400 WeakPolarHBondContact OG-CB 3.32Å; S397-S400 PolarHBondContact OG-N 3.17Å; S397-S400 PolarHBondContact OG-OG 2.93Å
401Q78.5Confident81.2Confident40 Ų4054.6 Ų54.619%0.18728%0.279CS..EExtended strand (participates in β ladder)trans-116.5122.8-172.4-69.4170.2-31.700108.5V377 L378 Y379 H435V377-Q401 PolarHBondContact O-N 3.13Å; L378-Q401 CarbonylContact C-O 3.28Å; L378-Q401 VanDerWaalsContact CA-O 3.3Å; L378-Q401 WeakPolarHBondContact CA-O 3.49Å; L378-Q401 HydrophobicContact CD1-CB 3.63Å; L378-Q401 WeakPolarHBondContact CD1-O 3.39Å; Y379-Q401 PolarHBondContact N-O 3.2Å; Q401-H435 PolarHBondContact NE2-CE1 3.24Å; Q401-H435 PolarHBondContact OE1-CE1 2.96Å; Q401-H435 PolarHBondContact OE1-ND1 3.07Å
402T90.9Very high81.2Confident31 Ų3154.4 Ų54.419%0.1928%0.278CS..EExtended strand (participates in β ladder)trans-102142.2173.555.90000110.4Y379 V392 D395Y379-T402 CarbonylContact O-C 3.54Å; Y379-T402 VanDerWaalsContact O-CA 3.32Å; Y379-T402 WeakPolarHBondContact O-CA 3.47Å; V392-T402 HydrophobicContact CG1-CG2 4.09Å; V392-T402 WeakPolarHBondContact O-CG2 3.44Å; D395-T402 VanDerWaalsContact OD1-CB 3.31Å; D395-T402 WeakPolarHBondContact OD1-CB 3.34Å; D395-T402 VanDerWaalsContact OD1-CG2 3.28Å; D395-T402 WeakPolarHBondContact OD1-CG2 3.33Å; D395-T402 PolarHBondContact OD1-N 3.21Å; D395-T402 PolarHBondContact OD1-OG1 3.33Å
403V94.6Very high81.4Confident4 Ų454.5 Ų54.52%0.02428%0.278CS..EExtended strand (participates in β ladder)trans-122.5109.2168.4173.20000107.4L378 Y379 V380 N381 I405 E431 I432L378-V403 HydrophobicContact CD1-CG2 3.7Å; L378-V403 HydrophobicContact CD2-CG2 4.36Å; L378-V403 HydrophobicContact CG-CG2 4.26Å; Y379-V403 PolarHBondContact O-N 2.96Å; V380-V403 CarbonylContact C-O 3.6Å; V380-V403 WeakPolarHBondContact CA-O 3.5Å; V380-V403 HydrophobicContact CG1-CB 4.27Å; V380-V403 HydrophobicContact CG1-CG1 4.24Å; V380-V403 HydrophobicContact CG2-CB 4.3Å; N381-V403 PolarHBondContact N-O 2.44Å; V403-I405 HydrophobicContact CG1-CD1 4.46Å; V403-I405 HydrophobicContact CG1-CG1 4.05Å; V403-E431 HydrophobicContact CG2-CB 4.34Å; V403-I432 HydrophobicContact CG1-CG1 4.49Å; V403-I432 HydrophobicContact CG2-CG1 4.49Å
404F95.1Very high81.9Confident106 Ų10653 Ų5347%0.46527%0.268SS..EExtended strand (participates in β ladder)trans-104.1117.5-179.5-174.4-99.7000111.1N381 G383 K388 K406N381-F404 HydrophobicContact CB-CD2 4.12Å; G383-F404 VanDerWaalsContact CA-CZ 3.47Å; K388-F404 HydrophobicContact CD-CE2 4.29Å; F404-K406 HydrophobicContact CE1-CB 4.4Å
405I95.6Very high82.6Confident6 Ų647.7 Ų47.73%0.03125%0.248CC..EExtended strand (participates in β ladder)trans-107.296.7-175.4-46.9178.6000109.5V380 N381 G382 G383 V403 D407 T408 D413 L425V380-I405 HydrophobicContact CG1-CD1 3.99Å; V380-I405 HydrophobicContact CG1-CG1 4.46Å; N381-I405 PolarHBondContact O-N 3.49Å; G382-I405 CarbonylContact C-O 3.28Å; G383-I405 PolarHBondContact N-O 2.86Å; V403-I405 HydrophobicContact CG1-CD1 4.46Å; V403-I405 HydrophobicContact CG1-CG1 4.05Å; I405-D407 PolarHBondContact O-N 3.3Å; I405-D407 VanDerWaalsContact O-N 3.1Å; I405-T408 HydrophobicContact CB-CG2 4.35Å; I405-T408 HydrophobicContact CG2-CG2 4.12Å; I405-T408 WeakPolarHBondContact CG2-OG1 3.31Å; I405-T408 PolarHBondContact O-N 2.85Å; I405-D413 HydrophobicContact CD1-CB 4.11Å; I405-L425 HydrophobicContact CD1-CD1 4.22Å
406K92.3Very high83.9Confident154 Ų15449 Ų4967%0.6725%0.249SC*.THydrogen-bonded Turntrans-50.9-38.1-162.4-175.2177.8177.4-178.20117.5G383 F404G383-K406 VanDerWaalsContact CA-O 3.27Å; G383-K406 WeakPolarHBondContact CA-O 3.38Å; F404-K406 HydrophobicContact CE1-CB 4.4Å
407D91.9Very high85.6Confident25 Ų2551.1 Ų51.113%0.13425%0.251CS..THydrogen-bonded Turntrans-125.337.1-171.163.8-33.7000111.3A174 V175 I405 R422 S424A174-D407 HydrophobicContact CB-CB 4.21Å; V175-D407 HydrophobicContact CG1-CB 3.97Å; I405-D407 PolarHBondContact O-N 3.3Å; I405-D407 VanDerWaalsContact O-N 3.1Å; D407-R422 WeakPolarHBondContact O-CD 3.12Å; D407-R422 WeakPolarHBondContact OD2-CD 3.37Å; D407-R422 IonicContact OD2-CZ 4Å; D407-R422 IonicContact OD2-NH1 3.83Å; D407-R422 PolarHBondContact OD2-NH1 2.95Å; D407-S424 WeakPolarHBondContact OD1-CB 3.36Å; D407-S424 PolarHBondContact OD1-OG 2.64Å
408T93.8Very high87.5Confident5 Ų552.3 Ų52.33%0.03125%0.247CC..  trans-123.1148.6-175.7-72.70000111.2G382 G383 V384 I405 A412 L425G382-T408 CarbonylContact C-O 3.48Å; G382-T408 VanDerWaalsContact C-O 3.28Å; G382-T408 WeakPolarHBondContact CA-O 3.39Å; G383-T408 PolarHBondContact N-O 2.97Å; G383-T408 VanDerWaalsContact N-O 3.16Å; V384-T408 WeakPolarHBondContact CG2-O 3.34Å; V384-T408 PolarHBondContact N-O 3.46Å; I405-T408 HydrophobicContact CB-CG2 4.35Å; I405-T408 HydrophobicContact CG2-CG2 4.12Å; I405-T408 WeakPolarHBondContact CG2-OG1 3.31Å; I405-T408 PolarHBondContact O-N 2.85Å; T408-A412 HydrophobicContact CG2-CB 3.4Å; T408-A412 VanDerWaalsContact CG2-CB 3.4Å; T408-L425 HydrophobicContact CG2-CD1 3.91Å
409A95.8Very high89.4Confident2 Ų251.4 Ų51.42%0.01725%0.248CC..  trans-86.2-176.7-176.100000112.6Q236 N238 E240 V384 C411Q236-A409 WeakPolarHBondContact O-CB 3.39Å; N238-A409 HydrophobicContact CB-CB 4.11Å; N238-A409 WeakPolarHBondContact O-CB 3.03Å; E240-A409 HydrophobicContact CG-CB 4.22Å; V384-A409 HydrophobicContact CG2-CB 4.44Å; A409-C411 PolarHBondContact O-N 3.04Å
410H97.5Very high91.3Very high7 Ų752.5 Ų52.53%0.03226%0.261CS..THydrogen-bonded Turntrans-63.8124.9-178.1-166.871.5000111.7S126 S150 Q236 D385 W387 A412S126-H410 WeakPolarHBondContact CB-NE2 3.21Å; S126-H410 PolarHBondContact OG-NE2 3.27Å; S150-H410 VanDerWaalsContact CB-CE1 3.48Å; S150-H410 WeakPolarHBondContact CB-CE1 3.28Å; S150-H410 VanDerWaalsContact CB-ND1 3.33Å; S150-H410 WeakPolarHBondContact CB-ND1 3.42Å; S150-H410 PolarHBondContact O-CE1 3.26Å; Q236-H410 HydrophobicContact CG-CB 3.58Å; Q236-H410 WeakPolarHBondContact O-CB 3.47Å; Q236-H410 PolarHBondContact O-N 2.91Å; D385-H410 HydrophobicContact CB-CB 4.36Å; D385-H410 IonicContact OD1-CG 3.42Å; D385-H410 IonicContact OD1-ND1 3.37Å; D385-H410 PolarHBondContact OD1-ND1 2.99Å; D385-H410 IonicContact OD2-CE1 3.1Å; D385-H410 IonicContact OD2-CG 2.66Å; D385-H410 IonicContact OD2-ND1 2.59Å; D385-H410 PolarHBondContact OD2-ND1 2.69Å; W387-H410 AromaticContact CD1-CE1 3.33Å; W387-H410 AromaticContact CD1-ND1 3.44Å; W387-H410 AromaticContact CD1-NE2 3.99Å; W387-H410 AromaticContact CG-CE1 3.63Å; W387-H410 AromaticContact CG-ND1 3.91Å; H410-A412 PolarHBondContact O-N 2.93Å
411C97Very high93.1Very high22 Ų2252.6 Ų52.615%0.14926%0.262CS..THydrogen-bonded Turntrans55.515.2177.8-57.10000116.5G125 S126 S149 S150 A409 D413 M414G125-C411 WeakPolarHBondContact CA-SG 3.5Å; S126-C411 PolarHBondContact N-SG 3.08Å; S149-C411 WeakPolarHBondContact OG-CA 3.29Å; S150-C411 PolarHBondContact OG-N 3.15Å; A409-C411 PolarHBondContact O-N 3.04Å; C411-D413 PolarHBondContact O-N 2.86Å; C411-M414 HydrophobicContact CB-SD 4.46Å; C411-M414 WeakPolarHBondContact O-CB 3.29Å; C411-M414 PolarHBondContact O-N 3.38Å
412A96.6Very high93.7Very high1 Ų153.2 Ų53.21%0.00826%0.262CS..G310 helixtrans-61.1-28.8-175.200000113.3E240 T408 H410 M414 S415 L425 R429E240-A412 HydrophobicContact CG-CB 3.64Å; E240-A412 WeakPolarHBondContact OE1-CB 3.02Å; T408-A412 HydrophobicContact CG2-CB 3.4Å; T408-A412 VanDerWaalsContact CG2-CB 3.4Å; H410-A412 PolarHBondContact O-N 2.93Å; A412-M414 PolarHBondContact O-N 3.19Å; A412-S415 WeakPolarHBondContact O-CB 3.42Å; A412-S415 PolarHBondContact O-N 3.31Å; A412-L425 HydrophobicContact CB-CD1 4.31Å; A412-L425 HydrophobicContact CB-CD2 4.28Å; A412-R429 PolarHBondContact O-NH2 3.27Å
413D97.1Very high93.9Very high4 Ų458.4 Ų58.42%0.02128%0.284CS..G310 helixtrans-59.8-31.1174.861.3-61.5000112.4H55 S149 V380 I405 C411 L425 R429 I432H55-D413 WeakPolarHBondContact CB-O 3.49Å; S149-D413 WeakPolarHBondContact CB-OD2 3.49Å; S149-D413 VanDerWaalsContact OG-CG 3.28Å; S149-D413 PolarHBondContact OG-OD1 2.93Å; S149-D413 PolarHBondContact OG-OD2 3.07Å; V380-D413 HydrophobicContact CG1-CB 4.23Å; I405-D413 HydrophobicContact CD1-CB 4.11Å; C411-D413 PolarHBondContact O-N 2.86Å; D413-L425 HydrophobicContact CB-CD1 4.26Å; D413-R429 HydrophobicContact CB-CG 4.44Å; D413-R429 PolarHBondContact O-NE 3.06Å; D413-I432 HydrophobicContact CB-CD1 3.84Å
414M96.8Very high94Very high31 Ų3159.6 Ų59.615%0.15329%0.293CS..G310 helixtrans-75.3-24.2-179.1-59.2-166.275.800113.5F39 G54 H55 F123 G125 C411 A412F39-M414 HydrophobicContact CD2-CE 4.11Å; F39-M414 HydrophobicContact CE2-CE 3.58Å; G54-M414 CarbonylContact C-O 3.49Å; G54-M414 VanDerWaalsContact CA-O 3.32Å; G54-M414 WeakPolarHBondContact CA-O 3.35Å; H55-M414 PolarHBondContact N-O 3.04Å; F123-M414 HydrophobicContact CB-CE 4.46Å; G125-M414 WeakPolarHBondContact CA-SD 3.36Å; G125-M414 PolarHBondContact N-SD 2.93Å; G125-M414 VanDerWaalsContact N-SD 3.35Å; C411-M414 HydrophobicContact CB-SD 4.46Å; C411-M414 WeakPolarHBondContact O-CB 3.29Å; C411-M414 PolarHBondContact O-N 3.38Å; A412-M414 PolarHBondContact O-N 3.19Å
415S93.9Very high94Very high44 Ų4454.8 Ų54.831%0.30827%0.272SS..SBendtrans-61.6153.4175.7-68.60000111.1E240 A412 R429E240-S415 PolarHBondContact OE2-OG 3.14Å; A412-S415 WeakPolarHBondContact O-CB 3.42Å; A412-S415 PolarHBondContact O-N 3.31Å; S415-R429 PolarHBondContact O-NE 2.93Å; S415-R429 PolarHBondContact O-NH2 3.15Å; S415-R429 VanDerWaalsContact O-NH2 3.13Å
416K91.5Very high94.1Very high126 Ų12659.6 Ų59.655%0.54829%0.29SS..PPolyproline II helixtrans-60.1141.4170.9-176.6172.9-177.6173.70110.1R418K416-R418 PolarHBondContact O-N 3.34Å
417E90.6Very high94.2Very high112 Ų11257.9 Ų57.952%0.52328%0.282SS..PPolyproline II helixtrans-59.4134.7177.7-170.3-178.7-171.600112.3R426E417-R426 WeakPolarHBondContact OE1-CD 3.2Å; E417-R426 WeakPolarHBondContact OE1-CG 3.4Å
418R91.8Very high94.4Very high79 Ų7956.8 Ų56.830%0.29828%0.277SS..  trans-119.1150.1174.3-55.2171.3-63.3-131.7-5.5110.1E240 K416 T420 D421E240-R418 VanDerWaalsContact CD-NH2 3.26Å; E240-R418 IonicContact OE1-CZ 3.25Å; E240-R418 IonicContact OE1-NH1 3.13Å; E240-R418 IonicContact OE1-NH2 2.62Å; E240-R418 PolarHBondContact OE1-NH2 3.37Å; E240-R418 IonicContact OE2-CZ 3.51Å; E240-R418 IonicContact OE2-NH1 3.56Å; E240-R418 PolarHBondContact OE2-NH1 2.78Å; E240-R418 IonicContact OE2-NH2 2.98Å; E240-R418 PolarHBondContact OE2-NH2 2.97Å; E240-R418 VanDerWaalsContact OE2-NH2 3.14Å; K416-R418 PolarHBondContact O-N 3.34Å; R418-T420 PolarHBondContact O-N 3.02Å; R418-T420 VanDerWaalsContact O-N 3.16Å; R418-D421 IonicContact CZ-OD1 3.94Å; R418-D421 PolarHBondContact N-OD2 3.26Å; R418-D421 IonicContact NE-OD1 2.77Å; R418-D421 PolarHBondContact NE-OD1 2.73Å; R418-D421 IonicContact NH2-OD1 2.73Å; R418-D421 PolarHBondContact NH2-OD1 2.78Å; R418-D421 VanDerWaalsContact O-CB 3.27Å; R418-D421 WeakPolarHBondContact O-CB 3.49Å; R418-D421 PolarHBondContact O-N 3.05Å
419L90.2Very high94.6Very high180 Ų18056.8 Ų56.894%0.94228%0.276SS*.THydrogen-bonded Turntrans-61.4-25.1176-65.2176.8000113.2D421L419-D421 VanDerWaalsContact C-N 3.29Å
420T90.3Very high94.6Very high120 Ų12061.3 Ų61.374%0.73630%0.297SS*.THydrogen-bonded Turntrans-83-5178.151.80000113.1R418 R422R418-T420 PolarHBondContact O-N 3.02Å; R418-T420 VanDerWaalsContact O-N 3.16Å; T420-R422 PolarHBondContact O-N 3.43Å
421D92.9Very high94.6Very high6 Ų664 Ų643%0.03231%0.31CS..  trans-65.2137.7-177-70.5-16.2000111.6R418 L419 L425 R426 R429R418-D421 IonicContact CZ-OD1 3.94Å; R418-D421 PolarHBondContact N-OD2 3.26Å; R418-D421 IonicContact NE-OD1 2.77Å; R418-D421 PolarHBondContact NE-OD1 2.73Å; R418-D421 IonicContact NH2-OD1 2.73Å; R418-D421 PolarHBondContact NH2-OD1 2.78Å; R418-D421 VanDerWaalsContact O-CB 3.27Å; R418-D421 WeakPolarHBondContact O-CB 3.49Å; R418-D421 PolarHBondContact O-N 3.05Å; L419-D421 VanDerWaalsContact C-N 3.29Å; D421-L425 HydrophobicContact CB-CD2 4.07Å; D421-L425 HydrophobicContact CB-CG 4.49Å; D421-R426 HydrophobicContact CB-CG 4.16Å; D421-R426 PolarHBondContact O-NE 3.39Å; D421-R426 PolarHBondContact O-NH2 2.98Å; D421-R426 VanDerWaalsContact O-NH2 3.08Å; D421-R429 IonicContact OD2-CZ 2.72Å; D421-R429 IonicContact OD2-NH1 3.79Å; D421-R429 PolarHBondContact OD2-NH1 3.17Å; D421-R429 IonicContact OD2-NH2 3.63Å
422R92.8Very high94.6Very high53 Ų5363 Ų6320%0.230%0.303CS..  trans-56.8148.7177.3-68.3163.9174.5-87.8-6110.4A174 E239 D407 T420 S424 L425 R426A174-R422 PolarHBondContact O-NH1 2.98Å; A174-R422 PolarHBondContact O-NH2 3.19Å; E239-R422 IonicContact OE1-CZ 3.17Å; E239-R422 IonicContact OE1-NE 2.71Å; E239-R422 IonicContact OE1-NH2 3.78Å; E239-R422 PolarHBondContact OE1-NH2 2.93Å; E239-R422 IonicContact OE2-CZ 2.66Å; E239-R422 IonicContact OE2-NE 2.78Å; E239-R422 PolarHBondContact OE2-NE 3.36Å; E239-R422 IonicContact OE2-NH2 3.4Å; D407-R422 WeakPolarHBondContact O-CD 3.12Å; D407-R422 WeakPolarHBondContact OD2-CD 3.37Å; D407-R422 IonicContact OD2-CZ 4Å; D407-R422 IonicContact OD2-NH1 3.83Å; D407-R422 PolarHBondContact OD2-NH1 2.95Å; T420-R422 PolarHBondContact O-N 3.43Å; R422-S424 VanDerWaalsContact C-N 3.26Å; R422-S424 PolarHBondContact O-N 3.33Å; R422-L425 HydrophobicContact CB-CB 4.44Å; R422-L425 PolarHBondContact O-N 2.04Å; R422-R426 PolarHBondContact O-N 2.82Å; R422-R426 VanDerWaalsContact O-N 3.1Å
423H94.9Very high94.6Very high139 Ų13964.8 Ų64.864%0.64431%0.311SS*.Hα-helixtrans-59.5-39.3-179175.4-87.8000112.1R426 K427H423-R426 PolarHBondContact O-N 3.45Å; H423-K427 WeakPolarHBondContact O-CB 3.26Å; H423-K427 PolarHBondContact O-N 2.73Å
424S95.4Very high94.6Very high29 Ų2968.4 Ų68.420%0.20333%0.331CS..Hα-helixtrans-58-46.2173.346.70000113.2D407 R422 K427 G428D407-S424 WeakPolarHBondContact OD1-CB 3.36Å; D407-S424 PolarHBondContact OD1-OG 2.64Å; R422-S424 VanDerWaalsContact C-N 3.26Å; R422-S424 PolarHBondContact O-N 3.33Å; S424-K427 PolarHBondContact O-N 3.06Å; S424-G428 PolarHBondContact O-N 3.08Å
425L96.4Very high94.5Very high5 Ų568 Ų683%0.02633%0.328CS..Hα-helixtrans-62.4-46.9177.7177.654000111.3I405 T408 A412 D413 D421 R422 K427 G428 R429I405-L425 HydrophobicContact CD1-CD1 4.22Å; T408-L425 HydrophobicContact CG2-CD1 3.91Å; A412-L425 HydrophobicContact CB-CD1 4.31Å; A412-L425 HydrophobicContact CB-CD2 4.28Å; D413-L425 HydrophobicContact CB-CD1 4.26Å; D421-L425 HydrophobicContact CB-CD2 4.07Å; D421-L425 HydrophobicContact CB-CG 4.49Å; R422-L425 HydrophobicContact CB-CB 4.44Å; R422-L425 PolarHBondContact O-N 2.04Å; L425-K427 VanDerWaalsContact C-N 3.33Å; L425-K427 PolarHBondContact O-N 3.36Å; L425-G428 PolarHBondContact O-N 3.46Å; L425-R429 PolarHBondContact O-N 3.21Å
426R96.1Very high94.7Very high108 Ų10866 Ų6641%0.40831%0.314SS..Hα-helixtrans-58.6-43.9174.3-74.3-179-80.7164.5-7.6112.1E417 D421 R422 H423 R429 Q430E417-R426 WeakPolarHBondContact OE1-CD 3.2Å; E417-R426 WeakPolarHBondContact OE1-CG 3.4Å; D421-R426 HydrophobicContact CB-CG 4.16Å; D421-R426 PolarHBondContact O-NE 3.39Å; D421-R426 PolarHBondContact O-NH2 2.98Å; D421-R426 VanDerWaalsContact O-NH2 3.08Å; R422-R426 PolarHBondContact O-N 2.82Å; R422-R426 VanDerWaalsContact O-N 3.1Å; H423-R426 PolarHBondContact O-N 3.45Å; R426-R429 PolarHBondContact O-N 2.96Å; R426-Q430 PolarHBondContact O-N 3.18Å
427K95.8Very high95Very high117 Ų11761.6 Ų61.651%0.50930%0.301SS..Hα-helixtrans-62.9-43.1175.3-168-171.5179.8-122.70111.8H423 S424 L425 Q430 E431H423-K427 WeakPolarHBondContact O-CB 3.26Å; H423-K427 PolarHBondContact O-N 2.73Å; S424-K427 PolarHBondContact O-N 3.06Å; L425-K427 VanDerWaalsContact C-N 3.33Å; L425-K427 PolarHBondContact O-N 3.36Å; K427-Q430 WeakPolarHBondContact O-CB 3.29Å; K427-Q430 PolarHBondContact O-N 2.81Å; K427-E431 WeakPolarHBondContact CE-OE1 3.32Å; K427-E431 IonicContact NZ-OE1 3.57Å; K427-E431 PolarHBondContact NZ-OE1 3.16Å; K427-E431 WeakPolarHBondContact O-CG 3.38Å; K427-E431 PolarHBondContact O-N 3.12Å
428G96.1Very high95.3Very high3 Ų361.8 Ų61.83%0.03130%0.297CS..Hα-helixtrans-59.7-45176.800000112.3S424 L425 Q430 E431 I432S424-G428 PolarHBondContact O-N 3.08Å; L425-G428 PolarHBondContact O-N 3.46Å; G428-Q430 PolarHBondContact O-N 2.93Å; G428-E431 WeakPolarHBondContact O-CB 3.41Å; G428-E431 PolarHBondContact O-N 3.1Å; G428-I432 VanDerWaalsContact O-CG1 3.29Å; G428-I432 WeakPolarHBondContact O-CG1 3.42Å; G428-I432 PolarHBondContact O-N 2.86Å
429R97.3Very high95.5Very high4 Ų458.8 Ų58.82%0.01529%0.286CS..Hα-helixtrans-60.2-43.9173.3-73.3-166.6-170.8117.3-0.5112.5H55 A412 D413 S415 D421 L425 R426 E431 I432 E433H55-R429 PolarHBondContact CE1-O 3.41Å; A412-R429 PolarHBondContact O-NH2 3.27Å; D413-R429 HydrophobicContact CB-CG 4.44Å; D413-R429 PolarHBondContact O-NE 3.06Å; S415-R429 PolarHBondContact O-NE 2.93Å; S415-R429 PolarHBondContact O-NH2 3.15Å; S415-R429 VanDerWaalsContact O-NH2 3.13Å; D421-R429 IonicContact OD2-CZ 2.72Å; D421-R429 IonicContact OD2-NH1 3.79Å; D421-R429 PolarHBondContact OD2-NH1 3.17Å; D421-R429 IonicContact OD2-NH2 3.63Å; L425-R429 PolarHBondContact O-N 3.21Å; R426-R429 PolarHBondContact O-N 2.96Å; R429-E431 VanDerWaalsContact C-N 3.3Å; R429-E431 PolarHBondContact O-N 3.24Å; R429-I432 WeakPolarHBondContact O-CB 3.47Å; R429-I432 PolarHBondContact O-N 3.43Å; R429-E433 WeakPolarHBondContact O-CG 3.36Å; R429-E433 PolarHBondContact O-N 3.04Å
430Q96.5Very high95.8Very high98 Ų9851.3 Ų51.346%0.45825%0.247SC..Hα-helixtrans-62-38.8176.1-172.563.984.200112.3R426 K427 G428 E433 N434R426-Q430 PolarHBondContact O-N 3.18Å; K427-Q430 WeakPolarHBondContact O-CB 3.29Å; K427-Q430 PolarHBondContact O-N 2.81Å; G428-Q430 PolarHBondContact O-N 2.93Å; Q430-E433 PolarHBondContact NE2-OE2 2.79Å; Q430-N434 WeakPolarHBondContact O-CB 3.48Å; Q430-N434 PolarHBondContact O-N 2.92Å; Q430-N434 VanDerWaalsContact O-N 3.07Å; Q430-N434 PolarHBondContact O-ND2 3.37Å
431E96.1Very high96.1Very high64 Ų6452.6 Ų52.630%0.29924%0.242SC..Hα-helixtrans-62.3-48.9173.6-72.7176.2-166.900110.3V403 K427 G428 R429 E433 N434 H435V403-E431 HydrophobicContact CG2-CB 4.34Å; K427-E431 WeakPolarHBondContact CE-OE1 3.32Å; K427-E431 IonicContact NZ-OE1 3.57Å; K427-E431 PolarHBondContact NZ-OE1 3.16Å; K427-E431 WeakPolarHBondContact O-CG 3.38Å; K427-E431 PolarHBondContact O-N 3.12Å; G428-E431 WeakPolarHBondContact O-CB 3.41Å; G428-E431 PolarHBondContact O-N 3.1Å; R429-E431 VanDerWaalsContact C-N 3.3Å; R429-E431 PolarHBondContact O-N 3.24Å; E431-E433 PolarHBondContact O-N 2.77Å; E431-N434 WeakPolarHBondContact O-CB 3.48Å; E431-N434 PolarHBondContact O-N 3.23Å; E431-N434 VanDerWaalsContact O-N 3.13Å; E431-H435 PolarHBondContact O-CD2 3.11Å; E431-H435 PolarHBondContact O-N 3.1Å
432I97.6Very high96.2Very high0 Ų055 Ų550%026%0.257CS..Hα-helixtrans-55.1-48.8176-65.2160.6000111.9M59 V147 L378 V380 V403 D413 G428 R429 N434 H435 V436M59-I432 HydrophobicContact CE-CG2 4.1Å; M59-I432 HydrophobicContact SD-CG2 4.29Å; V147-I432 HydrophobicContact CG1-CG2 4.11Å; V147-I432 HydrophobicContact CG2-CG2 4.31Å; L378-I432 HydrophobicContact CD2-CB 4.09Å; L378-I432 HydrophobicContact CD2-CG1 3.83Å; L378-I432 HydrophobicContact CD2-CG2 4.02Å; V380-I432 HydrophobicContact CB-CD1 4.43Å; V380-I432 HydrophobicContact CG1-CD1 3.89Å; V380-I432 HydrophobicContact CG2-CD1 3.73Å; V380-I432 HydrophobicContact CG2-CG1 3.83Å; V403-I432 HydrophobicContact CG1-CG1 4.49Å; V403-I432 HydrophobicContact CG2-CG1 4.49Å; D413-I432 HydrophobicContact CB-CD1 3.84Å; G428-I432 VanDerWaalsContact O-CG1 3.29Å; G428-I432 WeakPolarHBondContact O-CG1 3.42Å; G428-I432 PolarHBondContact O-N 2.86Å; R429-I432 WeakPolarHBondContact O-CB 3.47Å; R429-I432 PolarHBondContact O-N 3.43Å; I432-N434 VanDerWaalsContact C-N 3.32Å; I432-N434 PolarHBondContact O-N 3.29Å; I432-H435 WeakPolarHBondContact O-CB 3.35Å; I432-H435 PolarHBondContact O-N 3.2Å; I432-H435 VanDerWaalsContact O-N 3.09Å; I432-V436 PolarHBondContact O-N 3.33Å
433E97.7Very high96.3Very high39 Ų3952.5 Ų52.518%0.18225%0.248CC..Hα-helixtrans-55.3-46.9176-74162.7-161.500111.6H55 M59 R429 Q430 E431 H435 V436 A437H55-E433 IonicContact CD2-OE1 2.59Å; H55-E433 IonicContact CE1-OE1 2.71Å; H55-E433 WeakPolarHBondContact NE2-CG 3.47Å; H55-E433 IonicContact NE2-OE1 3.54Å; H55-E433 PolarHBondContact NE2-OE1 3.31Å; M59-E433 HydrophobicContact CG-CG 3.74Å; M59-E433 HydrophobicContact SD-CB 4.43Å; M59-E433 HydrophobicContact SD-CG 3.84Å; R429-E433 WeakPolarHBondContact O-CG 3.36Å; R429-E433 PolarHBondContact O-N 3.04Å; Q430-E433 PolarHBondContact NE2-OE2 2.79Å; E431-E433 PolarHBondContact O-N 2.77Å; E433-H435 VanDerWaalsContact C-N 3.27Å; E433-H435 PolarHBondContact O-N 2.67Å; E433-V436 PolarHBondContact O-N 2.96Å; E433-A437 VanDerWaalsContact O-CB 3.3Å; E433-A437 WeakPolarHBondContact O-CB 3.27Å; E433-A437 PolarHBondContact O-N 2.98Å
434N96.4Very high96.2Very high80 Ų8048 Ų4843%0.42823%0.234SC..Hα-helixtrans-63.3-32.3178.6-72.7-35.1000112.6Q430 E431 I432 R438Q430-N434 WeakPolarHBondContact O-CB 3.48Å; Q430-N434 PolarHBondContact O-N 2.92Å; Q430-N434 VanDerWaalsContact O-N 3.07Å; Q430-N434 PolarHBondContact O-ND2 3.37Å; E431-N434 WeakPolarHBondContact O-CB 3.48Å; E431-N434 PolarHBondContact O-N 3.23Å; E431-N434 VanDerWaalsContact O-N 3.13Å; I432-N434 VanDerWaalsContact C-N 3.32Å; I432-N434 PolarHBondContact O-N 3.29Å; N434-R438 WeakPolarHBondContact O-CB 3.46Å; N434-R438 VanDerWaalsContact O-CG 3.27Å; N434-R438 WeakPolarHBondContact O-CG 3.32Å; N434-R438 PolarHBondContact O-N 3.48Å; N434-R438 PolarHBondContact O-NE 3.47Å; N434-R438 VanDerWaalsContact O-NE 3.12Å
435H95.3Very high96.1Very high23 Ų2351 Ų5111%0.10625%0.248CC..Hα-helixtrans-68.8-50.1173.3-82.3-89.1000111.5L378 Q401 E431 I432 E433 A437 R438 W439L378-H435 HydrophobicContact CD1-CB 4.37Å; L378-H435 HydrophobicContact CD2-CB 3.91Å; Q401-H435 PolarHBondContact NE2-CE1 3.24Å; Q401-H435 PolarHBondContact OE1-CE1 2.96Å; Q401-H435 PolarHBondContact OE1-ND1 3.07Å; E431-H435 PolarHBondContact O-CD2 3.11Å; E431-H435 PolarHBondContact O-N 3.1Å; I432-H435 WeakPolarHBondContact O-CB 3.35Å; I432-H435 PolarHBondContact O-N 3.2Å; I432-H435 VanDerWaalsContact O-N 3.09Å; E433-H435 VanDerWaalsContact C-N 3.27Å; E433-H435 PolarHBondContact O-N 2.67Å; H435-A437 PolarHBondContact O-N 3.41Å; H435-R438 PolarHBondContact CD2-NH2 3.04Å; H435-R438 VanDerWaalsContact CD2-NH2 3.33Å; H435-R438 PolarHBondContact CE1-NH2 3.33Å; H435-R438 PolarHBondContact ND1-NH2 3.42Å; H435-R438 PolarHBondContact NE2-NH2 2.94Å; H435-R438 VanDerWaalsContact NE2-NH2 3.11Å; H435-R438 PolarHBondContact O-N 3.24Å; H435-W439 PolarHBondContact O-N 3.47Å
436V97.6Very high95.8Very high0 Ų054.5 Ų54.50%026%0.264CS..Hα-helixtrans-61.1-46.6179.3174.30000111.1F37 M59 F123 V147 I432 E433 R438 W439 L440F37-V436 HydrophobicContact CE1-CG1 4.32Å; F37-V436 HydrophobicContact CE2-CG1 4.42Å; F37-V436 HydrophobicContact CZ-CG1 3.68Å; M59-V436 HydrophobicContact SD-CB 4.21Å; M59-V436 HydrophobicContact SD-CG2 4.04Å; F123-V436 HydrophobicContact CE1-CG2 4.39Å; V147-V436 HydrophobicContact CG2-CG2 3.77Å; I432-V436 PolarHBondContact O-N 3.33Å; E433-V436 PolarHBondContact O-N 2.96Å; V436-R438 VanDerWaalsContact C-N 3.32Å; V436-R438 PolarHBondContact O-N 3.44Å; V436-W439 HydrophobicContact CG2-CE3 4.46Å; V436-W439 PolarHBondContact O-N 3.25Å; V436-L440 HydrophobicContact CG1-CD1 4.22Å; V436-L440 HydrophobicContact CG1-CG 4.48Å; V436-L440 WeakPolarHBondContact O-CG 3.46Å; V436-L440 PolarHBondContact O-N 3.2Å
437A97.6Very high95.3Very high35 Ų3552.6 Ų52.629%0.28926%0.259SS..Hα-helixtrans-59.5-41.3177.300000112.2E433 H435 L440 K441E433-A437 VanDerWaalsContact O-CB 3.3Å; E433-A437 WeakPolarHBondContact O-CB 3.27Å; E433-A437 PolarHBondContact O-N 2.98Å; H435-A437 PolarHBondContact O-N 3.41Å; A437-L440 PolarHBondContact O-N 3.16Å; A437-K441 WeakPolarHBondContact O-CB 3.47Å; A437-K441 PolarHBondContact O-N 3.28Å
438R96.1Very high94.6Very high116 Ų11654 Ų5444%0.43827%0.269SS..Hα-helixtrans-63.3-45.4174.5-82.5-175.5-66.4149.2-8.4111.8N434 H435 V436 L440 K441 T442N434-R438 WeakPolarHBondContact O-CB 3.46Å; N434-R438 VanDerWaalsContact O-CG 3.27Å; N434-R438 WeakPolarHBondContact O-CG 3.32Å; N434-R438 PolarHBondContact O-N 3.48Å; N434-R438 PolarHBondContact O-NE 3.47Å; N434-R438 VanDerWaalsContact O-NE 3.12Å; H435-R438 PolarHBondContact CD2-NH2 3.04Å; H435-R438 VanDerWaalsContact CD2-NH2 3.33Å; H435-R438 PolarHBondContact CE1-NH2 3.33Å; H435-R438 PolarHBondContact ND1-NH2 3.42Å; H435-R438 PolarHBondContact NE2-NH2 2.94Å; H435-R438 VanDerWaalsContact NE2-NH2 3.11Å; H435-R438 PolarHBondContact O-N 3.24Å; V436-R438 VanDerWaalsContact C-N 3.32Å; V436-R438 PolarHBondContact O-N 3.44Å; R438-L440 VanDerWaalsContact C-N 3.35Å; R438-L440 PolarHBondContact O-N 3.06Å; R438-K441 PolarHBondContact O-N 3.5Å; R438-T442 PolarHBondContact O-N 2.66Å; R438-T442 PolarHBondContact O-OG1 2.65Å; R438-T442 VanDerWaalsContact O-OG1 3.07Å
439W96.3Very high93.8Very high15 Ų1559 Ų596%0.05730%0.299CS..Hα-helixtrans-59.8-44.6177.2-72.6-22.5000112.3I121 Y144 A146 V147 R376 L378 H435 V436 K441 T442 A443I121-W439 HydrophobicContact CD1-CB 4.45Å; I121-W439 HydrophobicContact CD1-CE3 4.27Å; Y144-W439 HydrophobicContact CD1-CB 4.07Å; Y144-W439 HydrophobicContact CE1-CB 3.78Å; Y144-W439 HydrophobicContact CE1-CG 4.3Å; Y144-W439 WeakPolarHBondContact CE1-O 3.43Å; A146-W439 WeakPolarHBondContact O-CH2 3.37Å; V147-W439 HydrophobicContact CG2-CZ3 4.3Å; R376-W439 HydrophobicContact CB-CZ2 4.17Å; R376-W439 WeakPolarHBondContact O-CH2 3.4Å; L378-W439 HydrophobicContact CB-CH2 3.59Å; L378-W439 HydrophobicContact CB-CZ2 4.27Å; L378-W439 HydrophobicContact CB-CZ3 4.42Å; H435-W439 PolarHBondContact O-N 3.47Å; V436-W439 HydrophobicContact CG2-CE3 4.46Å; V436-W439 PolarHBondContact O-N 3.25Å; W439-K441 VanDerWaalsContact C-N 3.33Å; W439-K441 PolarHBondContact O-N 2.9Å; W439-T442 PolarHBondContact O-N 3.47Å; W439-A443 WeakPolarHBondContact O-CB 3.3Å; W439-A443 PolarHBondContact O-N 3.28Å
440L97.3Very high92.3Very high23 Ų2366.6 Ų66.612%0.1233%0.332CS..Hα-helixtrans-61-42.1176.7-67.8177.8000111.9P35 F37 H63 T119 I121 V436 A437 R438 A443 A444P35-L440 HydrophobicContact CB-CD2 3.69Å; P35-L440 HydrophobicContact CG-CD1 4.22Å; P35-L440 HydrophobicContact CG-CD2 4.18Å; F37-L440 HydrophobicContact CE1-CD1 4.21Å; F37-L440 HydrophobicContact CE1-CD2 4.5Å; F37-L440 HydrophobicContact CZ-CD1 4.19Å; H63-L440 HydrophobicContact CB-CD1 3.85Å; T119-L440 HydrophobicContact CG2-CD2 3.82Å; I121-L440 HydrophobicContact CD1-CD2 4.47Å; I121-L440 HydrophobicContact CG1-CD2 4.08Å; V436-L440 HydrophobicContact CG1-CD1 4.22Å; V436-L440 HydrophobicContact CG1-CG 4.48Å; V436-L440 WeakPolarHBondContact O-CG 3.46Å; V436-L440 PolarHBondContact O-N 3.2Å; A437-L440 PolarHBondContact O-N 3.16Å; R438-L440 VanDerWaalsContact C-N 3.35Å; R438-L440 PolarHBondContact O-N 3.06Å; L440-A443 PolarHBondContact O-N 3.38Å; L440-A444 PolarHBondContact O-N 2.9Å
441K96Very high90Very high148 Ų14867.6 Ų67.664%0.64335%0.347SS*.Hα-helixtrans-64.2-46.8175.6-174.7179178.6-179.50112A437 R438 W439 A443 A444 L445A437-K441 WeakPolarHBondContact O-CB 3.47Å; A437-K441 PolarHBondContact O-N 3.28Å; R438-K441 PolarHBondContact O-N 3.5Å; W439-K441 VanDerWaalsContact C-N 3.33Å; W439-K441 PolarHBondContact O-N 2.9Å; K441-A443 VanDerWaalsContact C-N 3.34Å; K441-A443 PolarHBondContact O-N 2.94Å; K441-A444 PolarHBondContact O-N 2.77Å; K441-L445 HydrophobicContact CG-CD1 4.39Å; K441-L445 WeakPolarHBondContact O-CG 3.34Å; K441-L445 PolarHBondContact O-N 3.21Å; K441-L445 VanDerWaalsContact O-N 3.08Å
442T95Very high88.1Confident56 Ų5668.4 Ų68.434%0.34437%0.372SS..Hα-helixtrans-61.4-43.6177.2-58.40000110.8Y144 R438 W439 A444 L445 E446Y144-T442 WeakPolarHBondContact OH-CB 3.47Å; Y144-T442 VanDerWaalsContact OH-CG2 3.27Å; Y144-T442 WeakPolarHBondContact OH-CG2 3.47Å; R438-T442 PolarHBondContact O-N 2.66Å; R438-T442 PolarHBondContact O-OG1 2.65Å; R438-T442 VanDerWaalsContact O-OG1 3.07Å; W439-T442 PolarHBondContact O-N 3.47Å; T442-A444 VanDerWaalsContact C-N 3.29Å; T442-A444 PolarHBondContact O-N 3.14Å; T442-L445 PolarHBondContact O-N 3.4Å; T442-L445 VanDerWaalsContact O-N 3.11Å; T442-E446 HydrophobicContact CG2-CG 4.3Å; T442-E446 WeakPolarHBondContact O-CG 2.82Å; T442-E446 PolarHBondContact O-N 3.03Å
443A95.1Very high85.3Confident1 Ų175.6 Ų75.61%0.00843%0.432CS..Hα-helixtrans-58.9-41.4177.200000111.7T119 Y144 W439 L440 K441 K447T119-A443 HydrophobicContact CG2-CB 3.63Å; T119-A443 WeakPolarHBondContact OG1-CB 3.33Å; Y144-A443 HydrophobicContact CD1-CB 4.2Å; Y144-A443 HydrophobicContact CD2-CB 3.81Å; Y144-A443 HydrophobicContact CE1-CB 3.88Å; Y144-A443 HydrophobicContact CE2-CB 3.42Å; Y144-A443 VanDerWaalsContact CE2-CB 3.42Å; Y144-A443 HydrophobicContact CG-CB 4.17Å; Y144-A443 VanDerWaalsContact CZ-CB 3.47Å; Y144-A443 PolarHBondContact OH-N 3.17Å; Y144-A443 VanDerWaalsContact OH-N 3.14Å; W439-A443 WeakPolarHBondContact O-CB 3.3Å; W439-A443 PolarHBondContact O-N 3.28Å; L440-A443 PolarHBondContact O-N 3.38Å; K441-A443 VanDerWaalsContact C-N 3.34Å; K441-A443 PolarHBondContact O-N 2.94Å; A443-K447 VanDerWaalsContact O-CD 3.28Å; A443-K447 WeakPolarHBondContact O-CD 3.35Å; A443-K447 WeakPolarHBondContact O-CG 3.26Å; A443-K447 PolarHBondContact O-N 2.76Å; A443-K447 VanDerWaalsContact O-N 3.16Å
444A92.9Very high84.7Confident43 Ų4377.4 Ų77.436%0.35544%0.444SS..Hα-helixtrans-63.9-41.4176.400000112.1L440 K441 T442 K447 M448L440-A444 PolarHBondContact O-N 2.9Å; K441-A444 PolarHBondContact O-N 2.77Å; T442-A444 VanDerWaalsContact C-N 3.29Å; T442-A444 PolarHBondContact O-N 3.14Å; A444-K447 PolarHBondContact O-N 3.5Å; A444-M448 WeakPolarHBondContact O-CG 3.33Å; A444-M448 PolarHBondContact O-N 3.41Å
445L92.4Very high84.1Confident92 Ų9277.3 Ų77.348%0.48245%0.445SS..Hα-helixtrans-67.7-41.7177.4-69169.7000112.7K441 T442 K447 M448 T449K441-L445 HydrophobicContact CG-CD1 4.39Å; K441-L445 WeakPolarHBondContact O-CG 3.34Å; K441-L445 PolarHBondContact O-N 3.21Å; K441-L445 VanDerWaalsContact O-N 3.08Å; T442-L445 PolarHBondContact O-N 3.4Å; T442-L445 VanDerWaalsContact O-N 3.11Å; L445-K447 VanDerWaalsContact C-N 3.26Å; L445-K447 PolarHBondContact O-N 3.15Å; L445-M448 PolarHBondContact O-N 2.98Å; L445-T449 WeakPolarHBondContact O-CG2 3.5Å; L445-T449 PolarHBondContact O-N 3.43Å; L445-T449 VanDerWaalsContact O-N 3.09Å; L445-T449 PolarHBondContact O-OG1 3.41Å
446E90.8Very high83.5Confident79 Ų7980.3 Ų80.337%0.36946%0.464SS..Hα-helixtrans-59.6-39.3175.9-73.7179.5174.500111.2Y144 R376 T442 T449 K450Y144-E446 WeakPolarHBondContact CE2-OE2 3.29Å; Y144-E446 PolarHBondContact OH-OE2 3.21Å; R376-E446 IonicContact CZ-OE1 3.14Å; R376-E446 IonicContact CZ-OE2 2.71Å; R376-E446 IonicContact NH1-OE1 3.55Å; R376-E446 IonicContact NH1-OE2 3.38Å; R376-E446 PolarHBondContact NH1-OE2 3.07Å; R376-E446 IonicContact NH2-OE1 2.78Å; R376-E446 PolarHBondContact NH2-OE1 3.44Å; R376-E446 IonicContact NH2-OE2 3.32Å; T442-E446 HydrophobicContact CG2-CG 4.3Å; T442-E446 WeakPolarHBondContact O-CG 2.82Å; T442-E446 PolarHBondContact O-N 3.03Å; E446-T449 PolarHBondContact O-N 3.49Å; E446-T449 PolarHBondContact O-OG1 3.29Å; E446-K450 PolarHBondContact O-N 3.22Å; E446-K450 VanDerWaalsContact O-N 3.15Å
447K84.7Confident82.6Confident69 Ų6985 Ų8530%0.349%0.491SS..Hα-helixtrans-68.4-34.8176.9-68.3164.5-170.7-172.80112.9S116 R117 T119 A443 A444 L445S116-K447 WeakPolarHBondContact O-CD 3.39Å; S116-K447 WeakPolarHBondContact O-CE 3.31Å; S116-K447 PolarHBondContact O-NZ 2.64Å; R117-K447 VanDerWaalsContact C-NZ 3.33Å; R117-K447 PolarHBondContact O-NZ 3.43Å; T119-K447 PolarHBondContact OG1-NZ 3.42Å; A443-K447 VanDerWaalsContact O-CD 3.28Å; A443-K447 WeakPolarHBondContact O-CD 3.35Å; A443-K447 WeakPolarHBondContact O-CG 3.26Å; A443-K447 PolarHBondContact O-N 2.76Å; A443-K447 VanDerWaalsContact O-N 3.16Å; A444-K447 PolarHBondContact O-N 3.5Å; L445-K447 VanDerWaalsContact C-N 3.26Å; L445-K447 PolarHBondContact O-N 3.15Å
448M81.9Confident81.7Confident146 Ų14688.1 Ų88.172%0.71950%0.504SS*.Hα-helixtrans-70.9-32.2176.3-69.9177.9-173.400112.6A444 L445A444-M448 WeakPolarHBondContact O-CG 3.33Å; A444-M448 PolarHBondContact O-N 3.41Å; L445-M448 PolarHBondContact O-N 2.98Å
449T79.1Confident80.7Confident109 Ų10986.3 Ų86.367%0.66951%0.508SS*.Hα-helixtrans-89-17.4-175.351.30000113.8L445 E446L445-T449 WeakPolarHBondContact O-CG2 3.5Å; L445-T449 PolarHBondContact O-N 3.43Å; L445-T449 VanDerWaalsContact O-N 3.09Å; L445-T449 PolarHBondContact O-OG1 3.41Å; E446-T449 PolarHBondContact O-N 3.49Å; E446-T449 PolarHBondContact O-OG1 3.29Å
450K65Low79.6Confident162 Ų16291.4 Ų91.470%0.70454%0.541SS*.SBendtrans-127.570.2173.6-66.3-177.9-179176.60112.2E446 G452E446-K450 PolarHBondContact O-N 3.22Å; E446-K450 VanDerWaalsContact O-N 3.15Å; K450-G452 PolarHBondContact O-N 3.33Å
451P49.6Very low78.3Confident119 Ų11996.6 Ų96.677%0.77357%0.573SS**THydrogen-bonded Turntrans-71.4100.6175.727.2-29.9000110.2
452G54.9Low76.8Confident81 Ų8192.3 Ų92.384%0.83557%0.567SS**THydrogen-bonded Turntrans127.818.4167.800000118.2K450K450-G452 PolarHBondContact O-N 3.33Å
453A40.1Very low75.1Confident151 Ų15195.6 Ų95.6100%1.24859%0.587SS**  trans-860167.500000111.9

Retrieved 453 of 453 residues in 1185 ms (Link to these results)