A0A087XDY3_POEFO Loading...

Cullin-1

AlphaFold DB , UniProt , Accession A0A087XDY3, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 776 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M31.4Very low32.1Very low242 Ų242154.3 Ų154.3100%1.19286%0.855SS**  01250-85.9-173.6168.200109
2S30.5Very low32.3Very low124 Ų124153.2 Ų153.287%0.86785%0.845SS**  trans36.4113.3158.6-59.60000121.6
3S32Very low32.8Very low118 Ų118155.7 Ų155.783%0.82584%0.843SS**  trans-135.9114.1149.6-33.90000107.6
4N32.3Very low33.4Very low152 Ų152159.1 Ų159.181%0.81385%0.85SS**  trans-150.3111.2169.3-107.4-12.7000107.7
5R33.3Very low34.8Very low219 Ų219153.5 Ų153.583%0.82682%0.819SS**  58.310692.1-86.8-171.4177.5-176.22.2113.8
6T31.1Very low36.7Very low148 Ų148146.6 Ų146.691%0.90880%0.796SS**  trans-112.2111.2157.135.80000108.8
7Q29.6Very low38.5Very low176 Ų176141.6 Ų141.682%0.82277%0.768SS**PPolyproline II helixtrans-85.2136.3169-85.9177.5-20.500109.3
8N29.2Very low40.5Very low160 Ų160139.2 Ų139.286%0.85675%0.754SS**PPolyproline II helixtrans-95.4117.3176.5-1508.4000108
9P32Very low42.3Very low99 Ų99138.6 Ų138.664%0.64375%0.746SS**SBendtrans-92.4126.4176.132-24000109.7
10H33.4Very low44.2Very low179 Ų179132.4 Ų132.483%0.82971%0.713SS**  trans93.667.8-177.7-50.6-63.1000116.1L12H10-L12 PolarHBondContact O-N 3.33Å
11G38.1Very low46Very low80 Ų80126.7 Ų126.783%0.82568%0.681SS**  trans-71.4117.8158.800000111.6
12L34.5Very low48.5Very low141 Ų141119.8 Ų119.874%0.73865%0.649SS**  trans-119.7113.7161.6-85.7156.1000106.8H10 Q14H10-L12 PolarHBondContact O-N 3.33Å; L12-Q14 PolarHBondContact O-N 2.74Å
13K38.4Very low51.1Low186 Ų186116.4 Ų116.481%0.80962%0.621SS**  trans-60.6131165.2-75.4-179.6176.5179.10107.3I15K13-I15 VanDerWaalsContact C-N 3.28Å; K13-I15 HydrophobicContact CB-CG1 4.04Å; K13-I15 PolarHBondContact O-N 3.39Å
14Q42.2Very low53.6Low204 Ų204110.8 Ų110.895%0.95358%0.582SS**  trans-65.792.9163.4-87.5177.8-22.300107.7L12L12-Q14 PolarHBondContact O-N 2.74Å
15I54.6Low56.1Low74 Ų74108.3 Ų108.338%0.37956%0.561SS.*  trans-87.9124.3173.5-56.2173.1000106.6K13 Q19 I20K13-I15 VanDerWaalsContact C-N 3.28Å; K13-I15 HydrophobicContact CB-CG1 4.04Å; K13-I15 PolarHBondContact O-N 3.39Å; I15-Q19 HydrophobicContact CG2-CB 3.73Å; I15-Q19 HydrophobicContact CG2-CG 3.86Å; I15-I20 HydrophobicContact CB-CD1 4.46Å; I15-I20 HydrophobicContact CB-CG1 4.11Å; I15-I20 HydrophobicContact CG2-CD1 4.45Å; I15-I20 HydrophobicContact CG2-CG1 3.6Å
16G64.5Low58.6Low43 Ų43100.3 Ų100.344%0.44354%0.542SS..  trans-64150176.400000111.7D18 Q19 I20G16-D18 PolarHBondContact O-N 3.39Å; G16-Q19 PolarHBondContact O-N 2.73Å; G16-I20 PolarHBondContact O-N 2.93Å; G16-I20 VanDerWaalsContact O-N 3.13Å
17L67.9Low61.2Low63 Ų6393.3 Ų93.333%0.3350%0.499SS..Hα-helixtrans-53.4-38.4-178.8-73.4168.8000112.5Q19 I20 W21 Y52 V84L17-Q19 PolarHBondContact O-N 3.21Å; L17-I20 PolarHBondContact O-N 2.83Å; L17-W21 PolarHBondContact O-N 3.4Å; L17-Y52 HydrophobicContact CB-CE2 4.09Å; L17-Y52 HydrophobicContact CD2-CD1 4.29Å; L17-Y52 HydrophobicContact CD2-CD2 3.83Å; L17-Y52 HydrophobicContact CD2-CE1 4.32Å; L17-Y52 HydrophobicContact CD2-CE2 3.89Å; L17-Y52 HydrophobicContact CD2-CG 4.04Å; L17-Y52 VanDerWaalsContact O-CE2 3.29Å; L17-Y52 WeakPolarHBondContact O-CE2 3.34Å; L17-V84 HydrophobicContact CD2-CG1 4.39Å
18D73.6Confident64Low97 Ų9784.9 Ų84.952%0.51946%0.459SS..Hα-helixtrans-67.2-35.1178.1-66.4-44.6000113.1G16 W21 D22 R91G16-D18 PolarHBondContact O-N 3.39Å; D18-W21 PolarHBondContact O-N 3.03Å; D18-D22 VanDerWaalsContact O-CG 3.32Å; D18-D22 PolarHBondContact O-N 3.01Å; D18-R91 IonicContact OD1-CZ 3.77Å; D18-R91 IonicContact OD1-NH1 3.75Å; D18-R91 PolarHBondContact OD1-NH1 3.01Å; D18-R91 IonicContact OD1-NH2 2.75Å; D18-R91 PolarHBondContact OD1-NH2 2.76Å
19Q75.7Confident66.7Low129 Ų12982.6 Ų82.660%0.60344%0.444SS*.Hα-helixtrans-72.8-29.9176.9-168.4166.433.500112.2I15 G16 L17 D23I15-Q19 HydrophobicContact CG2-CB 3.73Å; I15-Q19 HydrophobicContact CG2-CG 3.86Å; G16-Q19 PolarHBondContact O-N 2.73Å; L17-Q19 PolarHBondContact O-N 3.21Å; Q19-D23 PolarHBondContact O-N 3.2Å
20I78.8Confident69.3Low14 Ų1480 Ų807%0.07242%0.423CS..Hα-helixtrans-68.9-40.1169.7-60.2175.9000110.4I15 G16 L17 L24 H48 Y52I15-I20 HydrophobicContact CB-CD1 4.46Å; I15-I20 HydrophobicContact CB-CG1 4.11Å; I15-I20 HydrophobicContact CG2-CD1 4.45Å; I15-I20 HydrophobicContact CG2-CG1 3.6Å; G16-I20 PolarHBondContact O-N 2.93Å; G16-I20 VanDerWaalsContact O-N 3.13Å; L17-I20 PolarHBondContact O-N 2.83Å; I20-L24 WeakPolarHBondContact O-CB 3.4Å; I20-L24 PolarHBondContact O-N 3.45Å; I20-H48 HydrophobicContact CG2-CB 3.83Å; I20-Y52 HydrophobicContact CB-CD2 4.06Å; I20-Y52 HydrophobicContact CG2-CD2 3.79Å
21W82.8Confident71.9Confident13 Ų1372.1 Ų72.15%0.04939%0.387CS..Hα-helixtrans-66.9-40.7176.8174.1-105.4000112.6L17 D18 D23 L24 R25 Y52 L88 R91 L92L17-W21 PolarHBondContact O-N 3.4Å; D18-W21 PolarHBondContact O-N 3.03Å; W21-D23 PolarHBondContact O-N 2.72Å; W21-L24 HydrophobicContact CE3-CD2 3.98Å; W21-L24 HydrophobicContact CZ3-CD2 4.02Å; W21-L24 PolarHBondContact O-N 3.07Å; W21-R25 HydrophobicContact CZ2-CB 4.35Å; W21-R25 VanDerWaalsContact O-CB 3.23Å; W21-R25 WeakPolarHBondContact O-CB 3.45Å; W21-R25 PolarHBondContact O-N 3.14Å; W21-Y52 HydrophobicContact CB-CE2 4.17Å; W21-L88 HydrophobicContact CE3-CD1 3.56Å; W21-L88 HydrophobicContact CZ3-CD1 3.59Å; W21-R91 HydrophobicContact CD2-CB 4.08Å; W21-R91 HydrophobicContact CD2-CG 4.48Å; W21-R91 HydrophobicContact CE3-CB 4.1Å; W21-R91 VanDerWaalsContact CH2-C 3.45Å; W21-R91 HydrophobicContact CH2-CB 3.51Å; W21-R91 HydrophobicContact CZ2-CB 3.48Å; W21-R91 VanDerWaalsContact CZ2-CB 3.48Å; W21-R91 HydrophobicContact CZ2-CG 4.43Å; W21-R91 HydrophobicContact CZ3-CB 3.82Å; W21-L92 HydrophobicContact CH2-CD2 4Å; W21-L92 HydrophobicContact CH2-CG 4.24Å; W21-L92 HydrophobicContact CZ3-CD2 3.93Å; W21-L92 HydrophobicContact CZ3-CG 4.08Å
22D83.8Confident74.3Confident96 Ų9668.7 Ų68.751%0.51335%0.349SS..Hα-helixtrans-62.4-43.3178.8-72.5-25.2000111.8D18 R25 A26D18-D22 VanDerWaalsContact O-CG 3.32Å; D18-D22 PolarHBondContact O-N 3.01Å; D22-R25 PolarHBondContact O-N 3.33Å; D22-A26 PolarHBondContact O-N 2.93Å
23D84.5Confident76.7Confident53 Ų5365.4 Ų65.428%0.28334%0.336SS..Hα-helixtrans-68.6-39.9175.3-167.955.1000112.1Q19 W21 A26 G27 R41 H48Q19-D23 PolarHBondContact O-N 3.2Å; W21-D23 PolarHBondContact O-N 2.72Å; D23-A26 PolarHBondContact O-N 3.4Å; D23-G27 PolarHBondContact O-N 3.36Å; D23-R41 IonicContact OD1-CZ 3.01Å; D23-R41 IonicContact OD1-NH1 2.91Å; D23-R41 IonicContact OD1-NH2 2.74Å; D23-R41 PolarHBondContact OD1-NH2 3.45Å; D23-R41 IonicContact OD2-CZ 3.6Å; D23-R41 IonicContact OD2-NH1 3.58Å; D23-R41 PolarHBondContact OD2-NH1 3.31Å; D23-R41 IonicContact OD2-NH2 3.06Å; D23-R41 PolarHBondContact OD2-NH2 3.01Å; D23-H48 IonicContact OD2-CD2 3.22Å; D23-H48 IonicContact OD2-NE2 3.16Å
24L85Confident78.7Confident0 Ų063.7 Ų63.70%032%0.324CS..Hα-helixtrans-62.5-43.5174.6-175.266.7000111.1I20 W21 G27 I28 L45 V49 L88 I136I20-L24 WeakPolarHBondContact O-CB 3.4Å; I20-L24 PolarHBondContact O-N 3.45Å; W21-L24 HydrophobicContact CE3-CD2 3.98Å; W21-L24 HydrophobicContact CZ3-CD2 4.02Å; W21-L24 PolarHBondContact O-N 3.07Å; L24-G27 PolarHBondContact O-N 3Å; L24-I28 HydrophobicContact CD1-CD1 4.42Å; L24-I28 HydrophobicContact CD2-CD1 4.5Å; L24-I28 HydrophobicContact CG-CD1 3.91Å; L24-I28 HydrophobicContact CG-CG1 4.45Å; L24-I28 WeakPolarHBondContact O-CG1 3.33Å; L24-I28 PolarHBondContact O-N 3.06Å; L24-L45 HydrophobicContact CD1-CB 4.3Å; L24-L45 HydrophobicContact CD1-CD2 4.06Å; L24-V49 HydrophobicContact CD1-CG2 3.79Å; L24-V49 HydrophobicContact CD2-CG2 3.92Å; L24-L88 HydrophobicContact CD2-CD1 3.8Å; L24-I136 HydrophobicContact CD1-CG2 4.3Å
25R86.1Confident80.7Confident101 Ų10159.8 Ų59.838%0.38131%0.305SS..Hα-helixtrans-61.4-44.7176.5-177.1-174-121.6-169.40.7111W21 D22 G27 I28 Q29 F95W21-R25 HydrophobicContact CZ2-CB 4.35Å; W21-R25 VanDerWaalsContact O-CB 3.23Å; W21-R25 WeakPolarHBondContact O-CB 3.45Å; W21-R25 PolarHBondContact O-N 3.14Å; D22-R25 PolarHBondContact O-N 3.33Å; R25-G27 VanDerWaalsContact C-N 3.33Å; R25-G27 PolarHBondContact O-N 3.39Å; R25-I28 PolarHBondContact O-N 3.32Å; R25-Q29 WeakPolarHBondContact O-CB 3.38Å; R25-Q29 PolarHBondContact O-N 2.74Å; R25-F95 HydrophobicContact CG-CD2 4.13Å; R25-F95 HydrophobicContact CG-CE2 4.32Å
26A85.8Confident81.8Confident51 Ų5161.9 Ų61.942%0.42133%0.327SS..Hα-helixtrans-61.5-42175.100000111.5D22 D23 Q29 Q30D22-A26 PolarHBondContact O-N 2.93Å; D23-A26 PolarHBondContact O-N 3.4Å; A26-Q29 PolarHBondContact O-N 3.37Å; A26-Q30 PolarHBondContact O-N 3.23Å
27G85.4Confident82.7Confident0 Ų062.1 Ų62.10%032%0.317CS..Hα-helixtrans-63.8-40.9174.200000113.5D23 L24 R25 Q30 V31D23-G27 PolarHBondContact O-N 3.36Å; L24-G27 PolarHBondContact O-N 3Å; R25-G27 VanDerWaalsContact C-N 3.33Å; R25-G27 PolarHBondContact O-N 3.39Å; G27-Q30 WeakPolarHBondContact O-CB 3.44Å; G27-Q30 PolarHBondContact O-N 3.49Å; G27-V31 WeakPolarHBondContact O-CG2 3.47Å; G27-V31 PolarHBondContact O-N 3.45Å; G27-V31 VanDerWaalsContact O-N 3.14Å
28I86.9Confident83.6Confident0 Ų061.9 Ų61.90%032%0.324CS..Hα-helixtrans-67.3-41.3175.6-63.4166.1000110.2L24 R25 Q30 V31 Y32 L92 F95 L133L24-I28 HydrophobicContact CD1-CD1 4.42Å; L24-I28 HydrophobicContact CD2-CD1 4.5Å; L24-I28 HydrophobicContact CG-CD1 3.91Å; L24-I28 HydrophobicContact CG-CG1 4.45Å; L24-I28 WeakPolarHBondContact O-CG1 3.33Å; L24-I28 PolarHBondContact O-N 3.06Å; R25-I28 PolarHBondContact O-N 3.32Å; I28-Q30 VanDerWaalsContact C-N 3.28Å; I28-Q30 PolarHBondContact O-N 3.35Å; I28-V31 WeakPolarHBondContact O-CB 3.38Å; I28-V31 PolarHBondContact O-N 3.04Å; I28-V31 VanDerWaalsContact O-N 3.07Å; I28-Y32 HydrophobicContact CG2-CD2 3.76Å; I28-Y32 HydrophobicContact CG2-CE2 3.89Å; I28-Y32 WeakPolarHBondContact O-CD2 3.44Å; I28-Y32 PolarHBondContact O-N 3.45Å; I28-L92 HydrophobicContact CD1-CD2 3.35Å; I28-F95 HydrophobicContact CB-CE1 4.39Å; I28-F95 HydrophobicContact CB-CZ 4.37Å; I28-F95 HydrophobicContact CG2-CD1 3.75Å; I28-F95 HydrophobicContact CG2-CE1 3.29Å; I28-F95 HydrophobicContact CG2-CE2 4.44Å; I28-F95 HydrophobicContact CG2-CZ 3.68Å; I28-L133 HydrophobicContact CD1-CD1 3.87Å; I28-L133 HydrophobicContact CG1-CD1 3.73Å; I28-L133 HydrophobicContact CG2-CD1 4.05Å
29Q87.6Confident84.1Confident112 Ų11265.4 Ų65.452%0.52334%0.335SS..Hα-helixtrans-61.7-37.1174.9-171.6171.1-3.100111.8R25 A26 V31 Y32 T33 F95R25-Q29 WeakPolarHBondContact O-CB 3.38Å; R25-Q29 PolarHBondContact O-N 2.74Å; A26-Q29 PolarHBondContact O-N 3.37Å; Q29-V31 VanDerWaalsContact C-N 3.31Å; Q29-V31 PolarHBondContact O-N 3.49Å; Q29-Y32 PolarHBondContact O-N 2.92Å; Q29-T33 HydrophobicContact CG-CG2 4.43Å; Q29-T33 WeakPolarHBondContact O-CB 3.49Å; Q29-T33 WeakPolarHBondContact O-CG2 3.22Å; Q29-T33 PolarHBondContact O-N 3Å; Q29-T33 PolarHBondContact O-OG1 3.19Å; Q29-F95 HydrophobicContact CB-CE2 4.35Å; Q29-F95 HydrophobicContact CB-CZ 4.35Å
30Q86.7Confident84.5Confident44 Ų4462.9 Ų62.921%0.20633%0.332CS..Hα-helixtrans-59.6-40.7172-168.9-179.98.500112A26 G27 I28 T33 R34 Q35 S36 M37A26-Q30 PolarHBondContact O-N 3.23Å; G27-Q30 WeakPolarHBondContact O-CB 3.44Å; G27-Q30 PolarHBondContact O-N 3.49Å; I28-Q30 VanDerWaalsContact C-N 3.28Å; I28-Q30 PolarHBondContact O-N 3.35Å; Q30-T33 WeakPolarHBondContact CA-OG1 3.41Å; Q30-T33 PolarHBondContact O-OG1 3.16Å; Q30-R34 PolarHBondContact O-N 2.82Å; Q30-Q35 HydrophobicContact CG-CB 3.58Å; Q30-Q35 HydrophobicContact CG-CG 4.45Å; Q30-Q35 PolarHBondContact O-N 2.88Å; Q30-S36 PolarHBondContact NE2-O 2.92Å; Q30-M37 HydrophobicContact CB-CE 4.23Å; Q30-M37 HydrophobicContact CG-CE 4.3Å
31V87.7Confident84.9Confident14 Ų1464.5 Ų64.59%0.08534%0.337CS..Hα-helixtrans-66-48.9176.6174.50000111.3G27 I28 Q29 T33 R34 M37 S129 V132 I136G27-V31 WeakPolarHBondContact O-CG2 3.47Å; G27-V31 PolarHBondContact O-N 3.45Å; G27-V31 VanDerWaalsContact O-N 3.14Å; I28-V31 WeakPolarHBondContact O-CB 3.38Å; I28-V31 PolarHBondContact O-N 3.04Å; I28-V31 VanDerWaalsContact O-N 3.07Å; Q29-V31 VanDerWaalsContact C-N 3.31Å; Q29-V31 PolarHBondContact O-N 3.49Å; V31-T33 VanDerWaalsContact C-N 3.3Å; V31-T33 PolarHBondContact O-N 3.29Å; V31-R34 WeakPolarHBondContact O-CA 3.43Å; V31-R34 PolarHBondContact O-N 3.19Å; V31-M37 HydrophobicContact CG2-CE 3.64Å; V31-S129 PolarHBondContact O-OG 3.44Å; V31-V132 HydrophobicContact CG1-CB 3.87Å; V31-V132 HydrophobicContact CG1-CG1 3.84Å; V31-V132 HydrophobicContact CG2-CG1 4.04Å; V31-I136 HydrophobicContact CG2-CD1 4.12Å
32Y86.9Confident85.1Confident7 Ų767 Ų673%0.02735%0.347CS..Hα-helixtrans-72.8-19.5-178.2-82.2-94.9000113.8I28 Q29 R34 F95 L96 Y99 Y126 S130 L133I28-Y32 HydrophobicContact CG2-CD2 3.76Å; I28-Y32 HydrophobicContact CG2-CE2 3.89Å; I28-Y32 WeakPolarHBondContact O-CD2 3.44Å; I28-Y32 PolarHBondContact O-N 3.45Å; Q29-Y32 PolarHBondContact O-N 2.92Å; Y32-R34 VanDerWaalsContact C-N 3.29Å; Y32-F95 AromaticContact CD2-CE1 3.97Å; Y32-F95 HydrophobicContact CD2-CE1 3.97Å; Y32-F95 HydrophobicContact CE2-CE1 4.33Å; Y32-F95 HydrophobicContact CG-CE1 4.33Å; Y32-L96 HydrophobicContact CE1-CD2 4.08Å; Y32-L96 HydrophobicContact CE2-CD2 4.14Å; Y32-L96 WeakPolarHBondContact OH-CD2 3.42Å; Y32-Y99 AromaticContact CD1-CD1 3.99Å; Y32-Y99 HydrophobicContact CD1-CD1 3.99Å; Y32-Y99 AromaticContact CD1-CE1 3.79Å; Y32-Y99 HydrophobicContact CD1-CE1 3.79Å; Y32-Y99 HydrophobicContact CD1-CE2 4.37Å; Y32-Y99 HydrophobicContact CD1-CG 4.38Å; Y32-Y99 AromaticContact CD1-CZ 3.99Å; Y32-Y99 PolarHBondContact O-OH 3.17Å; Y32-Y126 HydrophobicContact CD1-CD2 4.07Å; Y32-Y126 HydrophobicContact CD1-CE2 4.25Å; Y32-Y126 AromaticContact CE1-CD2 3.5Å; Y32-Y126 HydrophobicContact CE1-CD2 3.5Å; Y32-Y126 AromaticContact CE1-CE2 3.45Å; Y32-Y126 HydrophobicContact CE1-CE2 3.45Å; Y32-Y126 VanDerWaalsContact CE1-CE2 3.45Å; Y32-Y126 HydrophobicContact CE1-CG 4.39Å; Y32-S130 WeakPolarHBondContact OH-CA 3.48Å; Y32-S130 PolarHBondContact OH-OG 3.3Å; Y32-L133 HydrophobicContact CE2-CB 4.3Å; Y32-L133 HydrophobicContact CE2-CD2 3.96Å
33T85.7Confident85.2Confident73 Ų7366.7 Ų66.745%0.44834%0.343SS..THydrogen-bonded Turntrans-88.75.6168.654.40000113.2Q29 Q30 V31 Q35Q29-T33 HydrophobicContact CG-CG2 4.43Å; Q29-T33 WeakPolarHBondContact O-CB 3.49Å; Q29-T33 WeakPolarHBondContact O-CG2 3.22Å; Q29-T33 PolarHBondContact O-N 3Å; Q29-T33 PolarHBondContact O-OG1 3.19Å; Q30-T33 WeakPolarHBondContact CA-OG1 3.41Å; Q30-T33 PolarHBondContact O-OG1 3.16Å; V31-T33 VanDerWaalsContact C-N 3.3Å; V31-T33 PolarHBondContact O-N 3.29Å; T33-Q35 PolarHBondContact O-N 2.99Å
34R80.8Confident85.2Confident150 Ų15068.3 Ų68.357%0.56635%0.349SS*.THydrogen-bonded Turntrans5133.7-178.1-49.6-150.3-32.1169.414115.7Q30 V31 Y32 D125Q30-R34 PolarHBondContact O-N 2.82Å; V31-R34 WeakPolarHBondContact O-CA 3.43Å; V31-R34 PolarHBondContact O-N 3.19Å; Y32-R34 VanDerWaalsContact C-N 3.29Å; R34-D125 VanDerWaalsContact CD-OD1 3.27Å; R34-D125 WeakPolarHBondContact CD-OD1 3.47Å; R34-D125 IonicContact CZ-OD1 3.4Å; R34-D125 IonicContact NE-OD1 3.51Å; R34-D125 IonicContact NH1-OD1 2.73Å; R34-D125 PolarHBondContact NH1-OD1 3.09Å
35Q84Confident85.3Confident121 Ų12168.3 Ų68.357%0.56535%0.349SS*.  trans-73.7140.9171.5-66.1179.83.500109.8Q30 T33 M37Q30-Q35 HydrophobicContact CG-CB 3.58Å; Q30-Q35 HydrophobicContact CG-CG 4.45Å; Q30-Q35 PolarHBondContact O-N 2.88Å; T33-Q35 PolarHBondContact O-N 2.99Å; Q35-M37 PolarHBondContact O-N 3.43Å
36S77.3Confident85.3Confident119 Ų11967 Ų6783%0.83235%0.345SS*.  trans-61.9129.1179600000110.8Q30Q30-S36 PolarHBondContact NE2-O 2.92Å
37M84.3Confident85.2Confident47 Ų4767.7 Ų67.723%0.23234%0.344CS..  trans-112.4128.5179.5-172.3178.1-71.700110.6Q30 V31 Q35 R41 L45Q30-M37 HydrophobicContact CB-CE 4.23Å; Q30-M37 HydrophobicContact CG-CE 4.3Å; V31-M37 HydrophobicContact CG2-CE 3.64Å; Q35-M37 PolarHBondContact O-N 3.43Å; M37-R41 HydrophobicContact CE-CG 4.44Å; M37-R41 HydrophobicContact CG-CB 3.79Å; M37-R41 HydrophobicContact CG-CG 3.79Å; M37-R41 HydrophobicContact SD-CB 4.45Å; M37-R41 HydrophobicContact SD-CG 4.1Å; M37-L45 HydrophobicContact CE-CD1 3.48Å; M37-L45 VanDerWaalsContact CE-CD1 3.48Å; M37-L45 HydrophobicContact SD-CD1 3.65Å
38A85.6Confident85Confident58 Ų5869.2 Ų69.248%0.47935%0.351SS..  trans-67.7148.5173.900000110.9S40 R41 Y42A38-S40 PolarHBondContact O-N 3.49Å; A38-R41 WeakPolarHBondContact O-CB 3.41Å; A38-R41 PolarHBondContact O-N 3.4Å; A38-Y42 PolarHBondContact O-N 3.44Å
39K84Confident84.7Confident171 Ų17169.2 Ų69.274%0.74335%0.351SS*.Hα-helixtrans-56.6-34.6178.1-175.2177.9178.7-178.60112.7M43K39-M43 WeakPolarHBondContact O-CG 3.46Å; K39-M43 PolarHBondContact O-N 3.21Å; K39-M43 VanDerWaalsContact O-N 3.09Å
40S84.3Confident84.5Confident77 Ų7768.7 Ų68.754%0.53835%0.345SS..Hα-helixtrans-59.5-48.6173.748.80000111.4A38 Y42 M43 E44A38-S40 PolarHBondContact O-N 3.49Å; S40-Y42 PolarHBondContact O-N 3.24Å; S40-M43 PolarHBondContact O-N 3.15Å; S40-E44 WeakPolarHBondContact O-CG 3.06Å; S40-E44 PolarHBondContact O-N 2.75Å
41R86.9Confident84.1Confident47 Ų4769.4 Ų69.418%0.17735%0.35CS..Hα-helixtrans-65.2-39.5179.4-17657.2174.1167.11.6112.8D23 M37 A38 M43 E44 L45D23-R41 IonicContact OD1-CZ 3.01Å; D23-R41 IonicContact OD1-NH1 2.91Å; D23-R41 IonicContact OD1-NH2 2.74Å; D23-R41 PolarHBondContact OD1-NH2 3.45Å; D23-R41 IonicContact OD2-CZ 3.6Å; D23-R41 IonicContact OD2-NH1 3.58Å; D23-R41 PolarHBondContact OD2-NH1 3.31Å; D23-R41 IonicContact OD2-NH2 3.06Å; D23-R41 PolarHBondContact OD2-NH2 3.01Å; M37-R41 HydrophobicContact CE-CG 4.44Å; M37-R41 HydrophobicContact CG-CB 3.79Å; M37-R41 HydrophobicContact CG-CG 3.79Å; M37-R41 HydrophobicContact SD-CB 4.45Å; M37-R41 HydrophobicContact SD-CG 4.1Å; A38-R41 WeakPolarHBondContact O-CB 3.41Å; A38-R41 PolarHBondContact O-N 3.4Å; R41-M43 VanDerWaalsContact C-N 3.31Å; R41-M43 PolarHBondContact O-N 3.25Å; R41-E44 VanDerWaalsContact CD-OE2 3.22Å; R41-E44 WeakPolarHBondContact CD-OE2 3.49Å; R41-E44 IonicContact NH1-OE2 2.83Å; R41-E44 PolarHBondContact NH1-OE2 3.25Å; R41-E44 VanDerWaalsContact NH1-OE2 3.16Å; R41-E44 WeakPolarHBondContact O-CB 3.47Å; R41-E44 PolarHBondContact O-N 3.48Å; R41-L45 WeakPolarHBondContact O-CG 3.48Å; R41-L45 PolarHBondContact O-N 3.19Å
42Y87.4Confident83.5Confident65 Ų6568.9 Ų68.926%0.25535%0.347SS..Hα-helixtrans-60-43.9173.4178.6-83.1000111.5A38 S40 L45 Y46 V132 G135 I136A38-Y42 PolarHBondContact O-N 3.44Å; S40-Y42 PolarHBondContact O-N 3.24Å; Y42-L45 PolarHBondContact O-N 3.36Å; Y42-Y46 PolarHBondContact O-N 2.99Å; Y42-V132 HydrophobicContact CD2-CG1 4.42Å; Y42-V132 HydrophobicContact CE2-CG1 4.12Å; Y42-G135 WeakPolarHBondContact OH-CA 3.21Å; Y42-G135 PolarHBondContact OH-O 2.95Å; Y42-I136 HydrophobicContact CD2-CD1 4.31Å; Y42-I136 HydrophobicContact CD2-CG1 3.85Å; Y42-I136 HydrophobicContact CE2-CD1 4.27Å; Y42-I136 HydrophobicContact CE2-CG1 3.48Å; Y42-I136 VanDerWaalsContact CE2-CG1 3.48Å; Y42-I136 PolarHBondContact OH-N 3.44Å
43M86.1Confident82.9Confident91 Ų9169.5 Ų69.545%0.44835%0.352SS..Hα-helixtrans-67.8-36.3177.6-71.9-61.5153.700112.2K39 S40 R41 Y46 T47K39-M43 WeakPolarHBondContact O-CG 3.46Å; K39-M43 PolarHBondContact O-N 3.21Å; K39-M43 VanDerWaalsContact O-N 3.09Å; S40-M43 PolarHBondContact O-N 3.15Å; R41-M43 VanDerWaalsContact C-N 3.31Å; R41-M43 PolarHBondContact O-N 3.25Å; M43-Y46 PolarHBondContact O-N 3.3Å; M43-T47 WeakPolarHBondContact O-CB 3.32Å; M43-T47 PolarHBondContact O-N 2.98Å; M43-T47 PolarHBondContact O-OG1 3.42Å
44E85.3Confident82.3Confident87 Ų8767.2 Ų67.241%0.40734%0.338SS..Hα-helixtrans-57.7-49.6171-73.7167-164.600111.3S40 R41 Y46 T47 H48S40-E44 WeakPolarHBondContact O-CG 3.06Å; S40-E44 PolarHBondContact O-N 2.75Å; R41-E44 VanDerWaalsContact CD-OE2 3.22Å; R41-E44 WeakPolarHBondContact CD-OE2 3.49Å; R41-E44 IonicContact NH1-OE2 2.83Å; R41-E44 PolarHBondContact NH1-OE2 3.25Å; R41-E44 VanDerWaalsContact NH1-OE2 3.16Å; R41-E44 WeakPolarHBondContact O-CB 3.47Å; R41-E44 PolarHBondContact O-N 3.48Å; E44-Y46 VanDerWaalsContact C-N 3.34Å; E44-Y46 PolarHBondContact O-N 3.29Å; E44-T47 CarbonylContact O-C 3.56Å; E44-T47 PolarHBondContact O-N 3.32Å; E44-T47 VanDerWaalsContact O-N 3.16Å; E44-H48 WeakPolarHBondContact O-CB 3.27Å; E44-H48 PolarHBondContact O-CD2 3.46Å; E44-H48 PolarHBondContact O-N 2.92Å
45L85.5Confident81.6Confident0 Ų061.9 Ų61.90%032%0.323CS..Hα-helixtrans-62.4-39.9178.9-64.9172.7000112.1L24 M37 R41 Y42 H48 V49 I136L24-L45 HydrophobicContact CD1-CB 4.3Å; L24-L45 HydrophobicContact CD1-CD2 4.06Å; M37-L45 HydrophobicContact CE-CD1 3.48Å; M37-L45 VanDerWaalsContact CE-CD1 3.48Å; M37-L45 HydrophobicContact SD-CD1 3.65Å; R41-L45 WeakPolarHBondContact O-CG 3.48Å; R41-L45 PolarHBondContact O-N 3.19Å; Y42-L45 PolarHBondContact O-N 3.36Å; L45-H48 WeakPolarHBondContact O-CB 3.39Å; L45-H48 PolarHBondContact O-N 3.09Å; L45-V49 WeakPolarHBondContact O-CG2 3.21Å; L45-V49 PolarHBondContact O-N 3.3Å; L45-I136 HydrophobicContact CB-CG2 3.87Å; L45-I136 HydrophobicContact CD1-CD1 4.13Å
46Y86.5Confident80.1Confident73 Ų7357.5 Ų57.529%0.28631%0.305SS..Hα-helixtrans-62.2-45.3172.9179-89.8000111.8Y42 M43 E44 H48 V49 Y50 I136 A138Y42-Y46 PolarHBondContact O-N 2.99Å; M43-Y46 PolarHBondContact O-N 3.3Å; E44-Y46 VanDerWaalsContact C-N 3.34Å; E44-Y46 PolarHBondContact O-N 3.29Å; Y46-H48 VanDerWaalsContact C-N 3.29Å; Y46-H48 PolarHBondContact O-N 3.39Å; Y46-V49 PolarHBondContact O-N 2.85Å; Y46-Y50 PolarHBondContact O-N 2.98Å; Y46-I136 WeakPolarHBondContact CD2-O 3.22Å; Y46-A138 HydrophobicContact CE2-CB 4.19Å
47T83.4Confident78.6Confident65 Ų6558.2 Ų58.240%0.39930%0.295SS..Hα-helixtrans-64.4-34175.6-63.30000111.5M43 E44 Y50 N51M43-T47 WeakPolarHBondContact O-CB 3.32Å; M43-T47 PolarHBondContact O-N 2.98Å; M43-T47 PolarHBondContact O-OG1 3.42Å; E44-T47 CarbonylContact O-C 3.56Å; E44-T47 PolarHBondContact O-N 3.32Å; E44-T47 VanDerWaalsContact O-N 3.16Å; T47-Y50 WeakPolarHBondContact O-CB 3.45Å; T47-Y50 PolarHBondContact O-N 3.45Å; T47-N51 VanDerWaalsContact O-CB 3.27Å; T47-N51 WeakPolarHBondContact O-CB 3.47Å; T47-N51 PolarHBondContact O-N 3.26Å; T47-N51 PolarHBondContact O-ND2 2.97Å
48H82.4Confident76.5Confident33 Ų3363.5 Ų63.515%0.15332%0.319CS..Hα-helixtrans-64.6-45.6173-77.7-56000111.6I20 D23 E44 L45 Y46 Y50 N51 Y52I20-H48 HydrophobicContact CG2-CB 3.83Å; D23-H48 IonicContact OD2-CD2 3.22Å; D23-H48 IonicContact OD2-NE2 3.16Å; E44-H48 WeakPolarHBondContact O-CB 3.27Å; E44-H48 PolarHBondContact O-CD2 3.46Å; E44-H48 PolarHBondContact O-N 2.92Å; L45-H48 WeakPolarHBondContact O-CB 3.39Å; L45-H48 PolarHBondContact O-N 3.09Å; Y46-H48 VanDerWaalsContact C-N 3.29Å; Y46-H48 PolarHBondContact O-N 3.39Å; H48-Y50 VanDerWaalsContact C-N 3.34Å; H48-Y50 PolarHBondContact O-N 3.32Å; H48-N51 PolarHBondContact O-N 3.01Å; H48-Y52 WeakPolarHBondContact O-CB 3.18Å; H48-Y52 PolarHBondContact O-N 3.38Å
49V81.3Confident74.3Confident0 Ų065 Ų650%033%0.326CS..Hα-helixtrans-60.4-44.3172.9174.30000111L24 L45 Y46 Y52 C53 L88 I136 L140L24-V49 HydrophobicContact CD1-CG2 3.79Å; L24-V49 HydrophobicContact CD2-CG2 3.92Å; L45-V49 WeakPolarHBondContact O-CG2 3.21Å; L45-V49 PolarHBondContact O-N 3.3Å; Y46-V49 PolarHBondContact O-N 2.85Å; V49-Y52 PolarHBondContact O-N 2.72Å; V49-C53 WeakPolarHBondContact O-CB 3.26Å; V49-C53 PolarHBondContact O-N 2.98Å; V49-C53 PolarHBondContact O-SG 3.48Å; V49-L88 HydrophobicContact CG1-CD2 4.17Å; V49-I136 HydrophobicContact CG2-CG2 4.05Å; V49-L140 HydrophobicContact CG1-CB 4.09Å
50Y81.9Confident72.1Confident101 Ų10161 Ų6140%0.39632%0.319SS..Hα-helixtrans-58.7-50.5175.7174.9-92.5000112.2Y46 T47 H48 Y52 C53 T54 Y139Y46-Y50 PolarHBondContact O-N 2.98Å; T47-Y50 WeakPolarHBondContact O-CB 3.45Å; T47-Y50 PolarHBondContact O-N 3.45Å; H48-Y50 VanDerWaalsContact C-N 3.34Å; H48-Y50 PolarHBondContact O-N 3.32Å; Y50-Y52 VanDerWaalsContact C-N 3.32Å; Y50-Y52 PolarHBondContact O-N 2.85Å; Y50-C53 PolarHBondContact O-N 2.82Å; Y50-T54 HydrophobicContact CD2-CG2 4.29Å; Y50-T54 HydrophobicContact CE1-CG2 4.19Å; Y50-T54 HydrophobicContact CE2-CG2 3.93Å; Y50-T54 WeakPolarHBondContact O-CB 3.38Å; Y50-T54 WeakPolarHBondContact O-CG2 3.39Å; Y50-T54 PolarHBondContact O-N 3.39Å; Y50-T54 PolarHBondContact O-OG1 3.3Å; Y50-Y139 AromaticContact CD2-CD1 3.99Å; Y50-Y139 HydrophobicContact CD2-CD1 3.99Å; Y50-Y139 AromaticContact CD2-CD2 3.57Å; Y50-Y139 HydrophobicContact CD2-CD2 3.57Å; Y50-Y139 AromaticContact CD2-CE1 3.86Å; Y50-Y139 HydrophobicContact CD2-CE1 3.86Å; Y50-Y139 AromaticContact CD2-CE2 3.42Å; Y50-Y139 HydrophobicContact CD2-CE2 3.42Å; Y50-Y139 VanDerWaalsContact CD2-CE2 3.42Å; Y50-Y139 AromaticContact CD2-CG 3.85Å; Y50-Y139 HydrophobicContact CD2-CG 3.85Å; Y50-Y139 AromaticContact CD2-CZ 3.57Å; Y50-Y139 HydrophobicContact CE2-CD2 4.08Å; Y50-Y139 HydrophobicContact CE2-CE1 4.26Å; Y50-Y139 AromaticContact CE2-CE2 3.47Å; Y50-Y139 HydrophobicContact CE2-CE2 3.47Å; Y50-Y139 VanDerWaalsContact CE2-CE2 3.47Å; Y50-Y139 AromaticContact CE2-CZ 3.57Å
51N79.8Confident69.9Low58 Ų5866 Ų6631%0.3133%0.334SS..Hα-helixtrans-63.5-39.6179.3-71.9-17.2000111.1T47 H48 T54 S55T47-N51 VanDerWaalsContact O-CB 3.27Å; T47-N51 WeakPolarHBondContact O-CB 3.47Å; T47-N51 PolarHBondContact O-N 3.26Å; T47-N51 PolarHBondContact O-ND2 2.97Å; H48-N51 PolarHBondContact O-N 3.01Å; N51-T54 WeakPolarHBondContact CA-OG1 3.29Å; N51-T54 PolarHBondContact O-N 3.3Å; N51-S55 WeakPolarHBondContact O-CA 3.41Å; N51-S55 VanDerWaalsContact O-CB 3.29Å; N51-S55 WeakPolarHBondContact O-CB 3.23Å; N51-S55 PolarHBondContact O-N 3.18Å
52Y75.1Confident67.6Low4 Ų468 Ų682%0.01636%0.36CS..Hα-helixtrans-60.8-48.4175.7-158-77.4000110.4L17 I20 W21 H48 V49 Y50 T54 S55 V84 L88L17-Y52 HydrophobicContact CB-CE2 4.09Å; L17-Y52 HydrophobicContact CD2-CD1 4.29Å; L17-Y52 HydrophobicContact CD2-CD2 3.83Å; L17-Y52 HydrophobicContact CD2-CE1 4.32Å; L17-Y52 HydrophobicContact CD2-CE2 3.89Å; L17-Y52 HydrophobicContact CD2-CG 4.04Å; L17-Y52 VanDerWaalsContact O-CE2 3.29Å; L17-Y52 WeakPolarHBondContact O-CE2 3.34Å; I20-Y52 HydrophobicContact CB-CD2 4.06Å; I20-Y52 HydrophobicContact CG2-CD2 3.79Å; W21-Y52 HydrophobicContact CB-CE2 4.17Å; H48-Y52 WeakPolarHBondContact O-CB 3.18Å; H48-Y52 PolarHBondContact O-N 3.38Å; V49-Y52 PolarHBondContact O-N 2.72Å; Y50-Y52 VanDerWaalsContact C-N 3.32Å; Y50-Y52 PolarHBondContact O-N 2.85Å; Y52-T54 VanDerWaalsContact C-N 3.35Å; Y52-T54 PolarHBondContact O-N 3.3Å; Y52-S55 PolarHBondContact O-OG 3.49Å; Y52-V84 HydrophobicContact CD1-CG1 3.55Å; Y52-V84 HydrophobicContact CE1-CG1 3.56Å; Y52-V84 WeakPolarHBondContact O-CG1 3.2Å; Y52-L88 HydrophobicContact CD1-CB 3.87Å; Y52-L88 HydrophobicContact CD1-CD1 4.2Å; Y52-L88 HydrophobicContact CD1-CD2 3.86Å; Y52-L88 HydrophobicContact CD1-CG 4.19Å; Y52-L88 HydrophobicContact CE1-CB 3.68Å; Y52-L88 HydrophobicContact CE1-CD1 4.17Å; Y52-L88 HydrophobicContact CE1-CD2 4.48Å; Y52-L88 HydrophobicContact CE1-CG 4.32Å; Y52-L88 HydrophobicContact CG-CD1 4.45Å; Y52-L88 HydrophobicContact CG-CD2 4.24Å
53C74.3Confident65Low20 Ų2076.6 Ų76.614%0.13539%0.393CS..Hα-helixtrans-68.8-26178.5-67.30000114.4V49 Y50 Y139V49-C53 WeakPolarHBondContact O-CB 3.26Å; V49-C53 PolarHBondContact O-N 2.98Å; V49-C53 PolarHBondContact O-SG 3.48Å; Y50-C53 PolarHBondContact O-N 2.82Å; C53-Y139 HydrophobicContact CB-CD1 3.84Å; C53-Y139 HydrophobicContact CB-CE1 3.75Å
54T72.8Confident62.5Low25 Ų2575.7 Ų75.715%0.15341%0.406CS..Hα-helixtrans-103.2-8.9-175.555.50000114.6Y50 N51 Y52 V56 H57 Y139Y50-T54 HydrophobicContact CD2-CG2 4.29Å; Y50-T54 HydrophobicContact CE1-CG2 4.19Å; Y50-T54 HydrophobicContact CE2-CG2 3.93Å; Y50-T54 WeakPolarHBondContact O-CB 3.38Å; Y50-T54 WeakPolarHBondContact O-CG2 3.39Å; Y50-T54 PolarHBondContact O-N 3.39Å; Y50-T54 PolarHBondContact O-OG1 3.3Å; N51-T54 WeakPolarHBondContact CA-OG1 3.29Å; N51-T54 PolarHBondContact O-N 3.3Å; Y52-T54 VanDerWaalsContact C-N 3.35Å; Y52-T54 PolarHBondContact O-N 3.3Å; T54-V56 PolarHBondContact O-N 2.95Å; T54-H57 PolarHBondContact O-N 2.74Å; T54-Y139 HydrophobicContact CG2-CE1 3.97Å; T54-Y139 WeakPolarHBondContact CG2-OH 3.23Å
55S65.3Low60Low38 Ų3877.3 Ų77.327%0.26643%0.427SS..Hα-helixtrans-50.6-24.9-178.458.60000115.2N51 Y52N51-S55 WeakPolarHBondContact O-CA 3.41Å; N51-S55 VanDerWaalsContact O-CB 3.29Å; N51-S55 WeakPolarHBondContact O-CB 3.23Å; N51-S55 PolarHBondContact O-N 3.18Å; Y52-S55 PolarHBondContact O-OG 3.49Å
56V52.4Low57.6Low28 Ų2884 Ų8417%0.1747%0.468CS..Hα-helixtrans-71.1-32178.3-177.60000112.4T54 Q58 S59 S60 G80 A81 V84T54-V56 PolarHBondContact O-N 2.95Å; V56-Q58 VanDerWaalsContact C-N 3.3Å; V56-Q58 PolarHBondContact O-N 3.22Å; V56-S59 PolarHBondContact O-N 2.96Å; V56-S59 PolarHBondContact O-OG 3.47Å; V56-S60 PolarHBondContact O-OG 2.87Å; V56-G80 WeakPolarHBondContact CG2-O 3.32Å; V56-A81 HydrophobicContact CB-CB 4.44Å; V56-V84 HydrophobicContact CG2-CB 4.27Å; V56-V84 HydrophobicContact CG2-CG2 3.54Å
57H45.5Very low55.4Low135 Ų13586 Ų8663%0.62549%0.49SS*.Hα-helixtrans-68.7-24.9-177.9-78.2-57.2000113.8T54T54-H57 PolarHBondContact O-N 2.74Å
58Q41.5Very low53.7Low157 Ų15789.2 Ų89.273%0.73451%0.512SS*.Hα-helixtrans-77.4-25.4177.7-79.7-176.8-700113.4V56V56-Q58 VanDerWaalsContact C-N 3.3Å; V56-Q58 PolarHBondContact O-N 3.22Å
59S38.3Very low51.3Low90 Ų9092.6 Ų92.663%0.62955%0.546SS*.Hα-helixtrans-78.4-19.1-178.567.40000114.1V56V56-S59 PolarHBondContact O-N 2.96Å; V56-S59 PolarHBondContact O-OG 3.47Å
60S38.2Very low49.1Very low87 Ų87102.6 Ų102.661%0.60859%0.589SS**SBendtrans-93.5-13-171.1-35.70000114.9V56V56-S60 PolarHBondContact O-OG 2.87Å
61Q38.4Very low47.4Very low182 Ų182103.1 Ų103.185%0.8561%0.605SS**SBendtrans-89.80.7-176.3-87.7-176.2-10.400115.1
62A37.9Very low44.8Very low88 Ų88105.7 Ų105.773%0.72763%0.627SS**SBendtrans-10217.4-171.600000116.3
63R33.9Very low42.8Very low247 Ų247114.9 Ų114.993%0.93267%0.667SS**SBendtrans-130.6118.7171.5-78.7-170.9177.8179.10.2112.2
64G33.1Very low41Very low71 Ų71124.5 Ų124.573%0.73271%0.707SS**  trans-78.1154.3-172.300000116.8
65S32.9Very low38.9Very low122 Ų122128 Ų12885%0.85373%0.732SS**  trans18.2111143.858.40000121.5
66V35.1Very low37.5Very low140 Ų140133.3 Ų133.385%0.84876%0.763SS**  trans-149142.5148-1780000109
67P39.4Very low36.5Very low116 Ų116137.5 Ų137.575%0.75379%0.789SS**  trans-86.6177.8-168.737-36.5000114.8
68P49Very low36.2Very low131 Ų131134.2 Ų134.285%0.85178%0.78SS**  trans-97.4150.6-13937.6-35.8000116
69A30.8Very low36.3Very low105 Ų105129 Ų12987%0.86877%0.769SS**  trans-125.6140.5160.100000110.8
70K34.4Very low37Very low209 Ų209126.5 Ų126.591%0.90976%0.757SS**  trans-77.9170.4-168.9-97-174.3-179.2177.80114
71P46.3Very low37.7Very low113 Ų113124.2 Ų124.273%0.73474%0.743SS**  trans-103.6161.8-137.539.8-35.8000114.6
72S27Very low38.6Very low111 Ų111117.9 Ų117.978%0.77671%0.713SS**  175.3156.6121.962.80000114.7
73K32.2Very low39.6Very low197 Ų197119.9 Ų119.986%0.85771%0.706SS**  trans85.4104.4166-67.3-173.5178.8178.10118.6S75K73-S75 PolarHBondContact O-N 3Å
74K37.4Very low41.4Very low222 Ų222109.1 Ų109.197%0.96567%0.668SS**  trans-44.6111.1173.4-69172.8173.2178.60112.4
75S27.2Very low43.4Very low99 Ų99105.8 Ų105.869%0.69263%0.634SS**  trans-119.3122.1151.256.40000107.1K73 T77K73-S75 PolarHBondContact O-N 3Å; S75-T77 PolarHBondContact O-N 3.18Å
76T35.7Very low45.6Very low149 Ų149102.5 Ų102.591%0.91461%0.606SS**  trans-81.186175.219.70000108.6
77T32.8Very low47.8Very low116 Ų11699.5 Ų99.571%0.71258%0.583SS**PPolyproline II helixtrans-74.9128168.4-33.50000108.7S75 G79S75-T77 PolarHBondContact O-N 3.18Å; T77-G79 PolarHBondContact O-N 3.3Å
78P38.8Very low49.9Very low67 Ų6794 Ų9444%0.43555%0.547SS..PPolyproline II helixtrans-70.4125179.6-5.219.6000109.5F83P78-F83 HydrophobicContact CB-CD2 4.48Å; P78-F83 HydrophobicContact CB-CE2 3.85Å; P78-F83 HydrophobicContact CG-CE2 4.04Å; P78-F83 HydrophobicContact CG-CZ 4.43Å
79G43.5Very low51.6Low48 Ų4888.2 Ų88.250%0.49551%0.508SS..PPolyproline II helixtrans-66.414417700000111.4T77 A81 Q82T77-G79 PolarHBondContact O-N 3.3Å; G79-A81 PolarHBondContact O-N 3.37Å; G79-Q82 VanDerWaalsContact O-CB 3.25Å; G79-Q82 WeakPolarHBondContact O-CB 3.48Å; G79-Q82 PolarHBondContact O-N 3.37Å
80G52.4Low54.2Low37 Ų3788.8 Ų88.838%0.38149%0.491SS..Hα-helixtrans-53-25.5-172.800000115.9V56 Q82 F83 V84V56-G80 WeakPolarHBondContact CG2-O 3.32Å; G80-Q82 PolarHBondContact O-N 3.01Å; G80-F83 PolarHBondContact O-N 3.42Å; G80-V84 PolarHBondContact O-N 3.36Å
81A52.5Low56.7Low39 Ų3981.1 Ų81.132%0.32246%0.457SS..Hα-helixtrans-63.1-26.2175.600000112.8V56 G79 G85V56-A81 HydrophobicContact CB-CB 4.44Å; G79-A81 PolarHBondContact O-N 3.37Å; A81-G85 PolarHBondContact O-N 2.99Å
82Q57.4Low58.6Low48 Ų4875.8 Ų75.822%0.22442%0.422CS..Hα-helixtrans-73.9-35.6179-161.2152.232.800112.3G79 G80 L86 W144 E148 E151G79-Q82 VanDerWaalsContact O-CB 3.25Å; G79-Q82 WeakPolarHBondContact O-CB 3.48Å; G79-Q82 PolarHBondContact O-N 3.37Å; G80-Q82 PolarHBondContact O-N 3.01Å; Q82-L86 WeakPolarHBondContact O-CB 3.48Å; Q82-L86 PolarHBondContact O-N 3.29Å; Q82-W144 PolarHBondContact O-NE1 3.18Å; Q82-E148 PolarHBondContact NE2-OE1 3.34Å; Q82-E151 PolarHBondContact NE2-OE2 3.34Å
83F60.8Low61.5Low130 Ų13075.3 Ų75.357%0.5741%0.406SS*.Hα-helixtrans-71-40177.2-81.1-84.7000112.5P78 G80 L86 E87P78-F83 HydrophobicContact CB-CD2 4.48Å; P78-F83 HydrophobicContact CB-CE2 3.85Å; P78-F83 HydrophobicContact CG-CE2 4.04Å; P78-F83 HydrophobicContact CG-CZ 4.43Å; G80-F83 PolarHBondContact O-N 3.42Å; F83-L86 PolarHBondContact O-N 3.01Å; F83-E87 WeakPolarHBondContact O-CB 3.48Å; F83-E87 PolarHBondContact O-N 3.13Å
84V69.7Low64.2Low21 Ų2171.3 Ų71.313%0.12739%0.39CS..Hα-helixtrans-73.1-37.7-176-177.80000112.2L17 Y52 V56 G80 L88L17-V84 HydrophobicContact CD2-CG1 4.39Å; Y52-V84 HydrophobicContact CD1-CG1 3.55Å; Y52-V84 HydrophobicContact CE1-CG1 3.56Å; Y52-V84 WeakPolarHBondContact O-CG1 3.2Å; V56-V84 HydrophobicContact CG2-CB 4.27Å; V56-V84 HydrophobicContact CG2-CG2 3.54Å; G80-V84 PolarHBondContact O-N 3.36Å; V84-L88 PolarHBondContact O-N 3.44Å; V84-L88 VanDerWaalsContact O-N 3.12Å
85G75.7Confident66.7Low2 Ų261.7 Ų61.72%0.02135%0.348CS..Hα-helixtrans-65-41173.400000113.1A81 L88 Y89 W144A81-G85 PolarHBondContact O-N 2.99Å; G85-L88 PolarHBondContact O-N 3.02Å; G85-Y89 WeakPolarHBondContact O-CB 3.37Å; G85-Y89 PolarHBondContact O-N 3.16Å; G85-W144 VanDerWaalsContact C-CE2 3.49Å
86L79.6Confident69.7Low53 Ų5357 Ų5728%0.27732%0.316SS..Hα-helixtrans-64.6-41.6176.8-178.263.6000112.1Q82 F83 Y89 K90 W144Q82-L86 WeakPolarHBondContact O-CB 3.48Å; Q82-L86 PolarHBondContact O-N 3.29Å; F83-L86 PolarHBondContact O-N 3.01Å; L86-Y89 PolarHBondContact O-N 2.84Å; L86-K90 WeakPolarHBondContact O-CG 3.27Å; L86-K90 PolarHBondContact O-N 3.37Å; L86-W144 HydrophobicContact CB-CH2 4.44Å; L86-W144 HydrophobicContact CB-CZ2 3.7Å; L86-W144 HydrophobicContact CD1-CH2 3.97Å; L86-W144 HydrophobicContact CD1-CZ2 3.86Å; L86-W144 HydrophobicContact CG-CZ2 4.4Å
87E81.6Confident72.3Confident77 Ų7755.5 Ų55.536%0.3630%0.297SS..Hα-helixtrans-63.5-46.6177.8-177.959.3-164.400111.4F83 Y89 K90 R91F83-E87 WeakPolarHBondContact O-CB 3.48Å; F83-E87 PolarHBondContact O-N 3.13Å; E87-Y89 VanDerWaalsContact C-N 3.35Å; E87-Y89 PolarHBondContact O-N 2.76Å; E87-K90 PolarHBondContact O-N 3.44Å; E87-R91 WeakPolarHBondContact O-CG 3.5Å; E87-R91 PolarHBondContact O-N 3.3Å; E87-R91 IonicContact OE1-CZ 3.59Å; E87-R91 IonicContact OE1-NE 2.78Å; E87-R91 PolarHBondContact OE1-NE 3.18Å; E87-R91 IonicContact OE1-NH2 3.2Å; E87-R91 PolarHBondContact OE1-NH2 3.28Å
88L82.6Confident75.1Confident0 Ų054 Ų540%028%0.284CS..Hα-helixtrans-60.3-44.6176.2-175.459.2000111.8W21 L24 V49 Y52 V84 G85 K90 R91 L92 L140W21-L88 HydrophobicContact CE3-CD1 3.56Å; W21-L88 HydrophobicContact CZ3-CD1 3.59Å; L24-L88 HydrophobicContact CD2-CD1 3.8Å; V49-L88 HydrophobicContact CG1-CD2 4.17Å; Y52-L88 HydrophobicContact CD1-CB 3.87Å; Y52-L88 HydrophobicContact CD1-CD1 4.2Å; Y52-L88 HydrophobicContact CD1-CD2 3.86Å; Y52-L88 HydrophobicContact CD1-CG 4.19Å; Y52-L88 HydrophobicContact CE1-CB 3.68Å; Y52-L88 HydrophobicContact CE1-CD1 4.17Å; Y52-L88 HydrophobicContact CE1-CD2 4.48Å; Y52-L88 HydrophobicContact CE1-CG 4.32Å; Y52-L88 HydrophobicContact CG-CD1 4.45Å; Y52-L88 HydrophobicContact CG-CD2 4.24Å; V84-L88 PolarHBondContact O-N 3.44Å; V84-L88 VanDerWaalsContact O-N 3.12Å; G85-L88 PolarHBondContact O-N 3.02Å; L88-K90 PolarHBondContact O-N 2.92Å; L88-R91 PolarHBondContact O-N 2.78Å; L88-L92 HydrophobicContact CG-CD1 4.21Å; L88-L92 VanDerWaalsContact O-CG 3.3Å; L88-L92 WeakPolarHBondContact O-CG 3.34Å; L88-L92 PolarHBondContact O-N 3.42Å; L88-L140 HydrophobicContact CD2-CD1 4.41Å; L88-L140 HydrophobicContact CD2-CD2 4.22Å; L88-L140 HydrophobicContact CG-CD2 4.41Å
89Y85.8Confident77.5Confident9 Ų953.6 Ų53.64%0.03527%0.274CS..Hα-helixtrans-62.1-41.5178.3-174.9-94000112.4G85 L86 E87 L92 K93 W144 V145 I156 Y157 I159 L162G85-Y89 WeakPolarHBondContact O-CB 3.37Å; G85-Y89 PolarHBondContact O-N 3.16Å; L86-Y89 PolarHBondContact O-N 2.84Å; E87-Y89 VanDerWaalsContact C-N 3.35Å; E87-Y89 PolarHBondContact O-N 2.76Å; Y89-L92 PolarHBondContact O-N 3.49Å; Y89-K93 WeakPolarHBondContact O-CB 3.3Å; Y89-K93 PolarHBondContact O-N 3.04Å; Y89-W144 HydrophobicContact CD1-CH2 4.19Å; Y89-W144 HydrophobicContact CD1-CZ3 4.18Å; Y89-W144 HydrophobicContact CD2-CE3 4.47Å; Y89-W144 HydrophobicContact CD2-CH2 4.45Å; Y89-W144 AromaticContact CD2-CZ3 3.65Å; Y89-W144 HydrophobicContact CD2-CZ3 3.65Å; Y89-W144 HydrophobicContact CE2-CZ3 4.37Å; Y89-W144 AromaticContact CG-CH2 3.91Å; Y89-W144 HydrophobicContact CG-CH2 3.91Å; Y89-W144 AromaticContact CG-CZ3 3.53Å; Y89-W144 HydrophobicContact CG-CZ3 3.53Å; Y89-V145 HydrophobicContact CD2-CG2 4.45Å; Y89-V145 HydrophobicContact CE2-CG2 4.47Å; Y89-I156 HydrophobicContact CE2-CG2 4.42Å; Y89-Y157 VanDerWaalsContact CE2-O 3.29Å; Y89-Y157 WeakPolarHBondContact CE2-O 3.3Å; Y89-Y157 PolarHBondContact OH-N 3.34Å; Y89-Y157 PolarHBondContact OH-O 2.79Å; Y89-I159 HydrophobicContact CD2-CD1 3.74Å; Y89-I159 HydrophobicContact CE2-CD1 3.85Å; Y89-L162 HydrophobicContact CD2-CD2 4.38Å; Y89-L162 HydrophobicContact CE1-CD2 4.34Å; Y89-L162 HydrophobicContact CE2-CD2 3.78Å
90K85.8Confident79.7Confident117 Ų11751.3 Ų51.351%0.50925%0.251SS..Hα-helixtrans-62.6-46.2174.2-77.6-179.9179.6179.30112L86 E87 L88 L92 K93 E94L86-K90 WeakPolarHBondContact O-CG 3.27Å; L86-K90 PolarHBondContact O-N 3.37Å; E87-K90 PolarHBondContact O-N 3.44Å; L88-K90 PolarHBondContact O-N 2.92Å; K90-L92 VanDerWaalsContact C-N 3.33Å; K90-L92 PolarHBondContact O-N 3.38Å; K90-K93 WeakPolarHBondContact O-CB 3.4Å; K90-K93 PolarHBondContact O-N 3.14Å; K90-E94 WeakPolarHBondContact O-CB 3.48Å; K90-E94 PolarHBondContact O-N 3.12Å
91R85.5Confident81.5Confident48 Ų4852.6 Ų52.618%0.18125%0.251CS..Hα-helixtrans-62.5-38.7178.6-69.8-176.2-177-162.2-0.3112D18 W21 E87 L88 F95D18-R91 IonicContact OD1-CZ 3.77Å; D18-R91 IonicContact OD1-NH1 3.75Å; D18-R91 PolarHBondContact OD1-NH1 3.01Å; D18-R91 IonicContact OD1-NH2 2.75Å; D18-R91 PolarHBondContact OD1-NH2 2.76Å; W21-R91 HydrophobicContact CD2-CB 4.08Å; W21-R91 HydrophobicContact CD2-CG 4.48Å; W21-R91 HydrophobicContact CE3-CB 4.1Å; W21-R91 VanDerWaalsContact CH2-C 3.45Å; W21-R91 HydrophobicContact CH2-CB 3.51Å; W21-R91 HydrophobicContact CZ2-CB 3.48Å; W21-R91 VanDerWaalsContact CZ2-CB 3.48Å; W21-R91 HydrophobicContact CZ2-CG 4.43Å; W21-R91 HydrophobicContact CZ3-CB 3.82Å; E87-R91 WeakPolarHBondContact O-CG 3.5Å; E87-R91 PolarHBondContact O-N 3.3Å; E87-R91 IonicContact OE1-CZ 3.59Å; E87-R91 IonicContact OE1-NE 2.78Å; E87-R91 PolarHBondContact OE1-NE 3.18Å; E87-R91 IonicContact OE1-NH2 3.2Å; E87-R91 PolarHBondContact OE1-NH2 3.28Å; L88-R91 PolarHBondContact O-N 2.78Å; R91-F95 WeakPolarHBondContact O-CB 3.47Å; R91-F95 PolarHBondContact O-N 2.68Å
92L87.3Confident83.2Confident1 Ų154.2 Ų54.21%0.00526%0.26CS..Hα-helixtrans-64.5-45.6172.7-71.8171.3000112.1W21 I28 L88 Y89 K90 E94 F95 L96 L133 L140 I159W21-L92 HydrophobicContact CH2-CD2 4Å; W21-L92 HydrophobicContact CH2-CG 4.24Å; W21-L92 HydrophobicContact CZ3-CD2 3.93Å; W21-L92 HydrophobicContact CZ3-CG 4.08Å; I28-L92 HydrophobicContact CD1-CD2 3.35Å; L88-L92 HydrophobicContact CG-CD1 4.21Å; L88-L92 VanDerWaalsContact O-CG 3.3Å; L88-L92 WeakPolarHBondContact O-CG 3.34Å; L88-L92 PolarHBondContact O-N 3.42Å; Y89-L92 PolarHBondContact O-N 3.49Å; K90-L92 VanDerWaalsContact C-N 3.33Å; K90-L92 PolarHBondContact O-N 3.38Å; L92-E94 VanDerWaalsContact C-N 3.33Å; L92-E94 PolarHBondContact O-N 3.29Å; L92-F95 PolarHBondContact O-N 3.43Å; L92-L96 WeakPolarHBondContact O-CG 3.49Å; L92-L96 PolarHBondContact O-N 2.87Å; L92-L133 HydrophobicContact CD2-CD1 4.35Å; L92-L140 HydrophobicContact CD1-CD2 3.97Å; L92-I159 HydrophobicContact CD1-CD1 3.86Å
93K87.9Confident84.7Confident102 Ų10252.6 Ų52.644%0.44325%0.253SS..Hα-helixtrans-59-43.8176.1-178.2171.7-175.8175.80111.9Y89 K90 L96 K97 L162Y89-K93 WeakPolarHBondContact O-CB 3.3Å; Y89-K93 PolarHBondContact O-N 3.04Å; K90-K93 WeakPolarHBondContact O-CB 3.4Å; K90-K93 PolarHBondContact O-N 3.14Å; K93-L96 PolarHBondContact O-N 3.29Å; K93-K97 WeakPolarHBondContact O-CB 3.34Å; K93-K97 PolarHBondContact O-N 3.02Å; K93-L162 HydrophobicContact CB-CD1 4.33Å; K93-L162 HydrophobicContact CB-CD2 4.08Å; K93-L162 HydrophobicContact CD-CD1 4.01Å; K93-L162 HydrophobicContact CG-CD1 4Å
94E88.5Confident86.1Confident113 Ų11347.3 Ų47.353%0.52823%0.231SC..Hα-helixtrans-67.6-39.6179-170.3170.6-166.300112.1K90 L92 K97 N98K90-E94 WeakPolarHBondContact O-CB 3.48Å; K90-E94 PolarHBondContact O-N 3.12Å; L92-E94 VanDerWaalsContact C-N 3.33Å; L92-E94 PolarHBondContact O-N 3.29Å; E94-K97 PolarHBondContact O-N 2.91Å; E94-N98 WeakPolarHBondContact O-CB 3.15Å; E94-N98 VanDerWaalsContact O-CG 3.25Å; E94-N98 PolarHBondContact O-N 3Å; E94-N98 PolarHBondContact O-ND2 2.91Å
95F90.5Very high86.9Confident19 Ų1953.4 Ų53.48%0.08326%0.255CS..Hα-helixtrans-57.3-50.7172.1175.4-87.6000111.7R25 I28 Q29 Y32 R91 L92 K97 N98 Y99R25-F95 HydrophobicContact CG-CD2 4.13Å; R25-F95 HydrophobicContact CG-CE2 4.32Å; I28-F95 HydrophobicContact CB-CE1 4.39Å; I28-F95 HydrophobicContact CB-CZ 4.37Å; I28-F95 HydrophobicContact CG2-CD1 3.75Å; I28-F95 HydrophobicContact CG2-CE1 3.29Å; I28-F95 HydrophobicContact CG2-CE2 4.44Å; I28-F95 HydrophobicContact CG2-CZ 3.68Å; Q29-F95 HydrophobicContact CB-CE2 4.35Å; Q29-F95 HydrophobicContact CB-CZ 4.35Å; Y32-F95 AromaticContact CD2-CE1 3.97Å; Y32-F95 HydrophobicContact CD2-CE1 3.97Å; Y32-F95 HydrophobicContact CE2-CE1 4.33Å; Y32-F95 HydrophobicContact CG-CE1 4.33Å; R91-F95 WeakPolarHBondContact O-CB 3.47Å; R91-F95 PolarHBondContact O-N 2.68Å; L92-F95 PolarHBondContact O-N 3.43Å; F95-K97 VanDerWaalsContact C-N 3.32Å; F95-K97 PolarHBondContact O-N 2.83Å; F95-N98 PolarHBondContact O-N 3.42Å; F95-Y99 WeakPolarHBondContact O-CB 3.42Å; F95-Y99 PolarHBondContact O-N 3.31Å
96L90.2Very high87.4Confident1 Ų158.5 Ų58.51%0.00528%0.282CS..Hα-helixtrans-61-41.4179.7-67169.3000111.6Y32 L92 K93 L100 Y126 L133 L162 A163 T166Y32-L96 HydrophobicContact CE1-CD2 4.08Å; Y32-L96 HydrophobicContact CE2-CD2 4.14Å; Y32-L96 WeakPolarHBondContact OH-CD2 3.42Å; L92-L96 WeakPolarHBondContact O-CG 3.49Å; L92-L96 PolarHBondContact O-N 2.87Å; K93-L96 PolarHBondContact O-N 3.29Å; L96-L100 WeakPolarHBondContact O-CB 3.33Å; L96-L100 WeakPolarHBondContact O-CG 3.37Å; L96-L100 PolarHBondContact O-N 2.95Å; L96-Y126 HydrophobicContact CD2-CE2 4.42Å; L96-L133 HydrophobicContact CD1-CD2 4.45Å; L96-L133 HydrophobicContact CD2-CD2 4.02Å; L96-L162 HydrophobicContact CD1-CD2 4.25Å; L96-L162 HydrophobicContact CD1-CG 4.26Å; L96-A163 HydrophobicContact CD1-CB 4.24Å; L96-T166 HydrophobicContact CB-CG2 4.05Å
97K90.5Very high87.4Confident118 Ų11856 Ų5651%0.51327%0.269SS..Hα-helixtrans-63.3-46.6177.4-171.7179.4-178.1-174.90111.6K93 E94 F95 L100 T101 T166K93-K97 WeakPolarHBondContact O-CB 3.34Å; K93-K97 PolarHBondContact O-N 3.02Å; E94-K97 PolarHBondContact O-N 2.91Å; F95-K97 VanDerWaalsContact C-N 3.32Å; F95-K97 PolarHBondContact O-N 2.83Å; K97-L100 PolarHBondContact O-N 3.3Å; K97-T101 WeakPolarHBondContact O-CB 3.45Å; K97-T101 PolarHBondContact O-N 2.84Å; K97-T101 PolarHBondContact O-OG1 2.89Å; K97-T166 HydrophobicContact CB-CG2 4.19Å
98N89.8Confident87.5Confident85 Ų8557 Ų5746%0.45527%0.274SS..Hα-helixtrans-66.2-41-179.5-70.2-13.4000111.8E94 F95 T101 S102E94-N98 WeakPolarHBondContact O-CB 3.15Å; E94-N98 VanDerWaalsContact O-CG 3.25Å; E94-N98 PolarHBondContact O-N 3Å; E94-N98 PolarHBondContact O-ND2 2.91Å; F95-N98 PolarHBondContact O-N 3.42Å; N98-T101 PolarHBondContact O-N 3.48Å; N98-S102 PolarHBondContact O-N 3.06Å
99Y90.3Very high87.7Confident58 Ų5864.3 Ų64.323%0.22731%0.313CS..Hα-helixtrans-57.6-51.6174.3178.3-94.2000111.3Y32 F95 T101 S102 L103 Y126Y32-Y99 AromaticContact CD1-CD1 3.99Å; Y32-Y99 HydrophobicContact CD1-CD1 3.99Å; Y32-Y99 AromaticContact CD1-CE1 3.79Å; Y32-Y99 HydrophobicContact CD1-CE1 3.79Å; Y32-Y99 HydrophobicContact CD1-CE2 4.37Å; Y32-Y99 HydrophobicContact CD1-CG 4.38Å; Y32-Y99 AromaticContact CD1-CZ 3.99Å; Y32-Y99 PolarHBondContact O-OH 3.17Å; F95-Y99 WeakPolarHBondContact O-CB 3.42Å; F95-Y99 PolarHBondContact O-N 3.31Å; Y99-T101 PolarHBondContact O-N 3.44Å; Y99-S102 PolarHBondContact O-N 3.41Å; Y99-L103 HydrophobicContact CE1-CD2 4.16Å; Y99-L103 WeakPolarHBondContact O-CB 3.37Å; Y99-L103 PolarHBondContact O-N 3.3Å; Y99-Y126 HydrophobicContact CD1-CD2 4.22Å; Y99-Y126 HydrophobicContact CD1-CE2 4.17Å; Y99-Y126 AromaticContact CE1-CD2 3.98Å; Y99-Y126 HydrophobicContact CE1-CD2 3.98Å; Y99-Y126 HydrophobicContact CE1-CE2 4.39Å
100L90.3Very high87.8Confident0 Ų066.5 Ų66.50%033%0.325CS..Hα-helixtrans-68.7-34-178.8-70.9171.4000113.4L96 K97 S102 L103 L104 Y126 T166 W167 C170L96-L100 WeakPolarHBondContact O-CB 3.33Å; L96-L100 WeakPolarHBondContact O-CG 3.37Å; L96-L100 PolarHBondContact O-N 2.95Å; K97-L100 PolarHBondContact O-N 3.3Å; L100-S102 VanDerWaalsContact C-N 3.32Å; L100-L103 HydrophobicContact CD2-CD2 4.28Å; L100-L103 PolarHBondContact O-N 2.93Å; L100-L104 WeakPolarHBondContact O-CB 3.4Å; L100-L104 PolarHBondContact O-N 2.81Å; L100-Y126 HydrophobicContact CD1-CE2 3.91Å; L100-Y126 WeakPolarHBondContact CD1-OH 3.2Å; L100-Y126 HydrophobicContact CD2-CD2 3.8Å; L100-Y126 HydrophobicContact CD2-CE2 3.59Å; L100-Y126 HydrophobicContact CG-CD2 4.49Å; L100-Y126 HydrophobicContact CG-CE2 3.8Å; L100-T166 VanDerWaalsContact CD1-C 3.49Å; L100-T166 HydrophobicContact CD1-CG2 3.76Å; L100-W167 HydrophobicContact CD1-CB 4.38Å; L100-W167 HydrophobicContact CD2-CE3 3.58Å; L100-W167 HydrophobicContact CD2-CZ3 3.94Å; L100-C170 HydrophobicContact CB-CB 3.75Å; L100-C170 HydrophobicContact CD1-CB 4.28Å
101T89.3Confident87.8Confident63 Ų6365.6 Ų65.639%0.38732%0.324SS..Hα-helixtrans-67.9-35.1175.8-52.20000111.3K97 N98 Y99K97-T101 WeakPolarHBondContact O-CB 3.45Å; K97-T101 PolarHBondContact O-N 2.84Å; K97-T101 PolarHBondContact O-OG1 2.89Å; N98-T101 PolarHBondContact O-N 3.48Å; Y99-T101 PolarHBondContact O-N 3.44Å
102S88.7Confident87.8Confident74 Ų7466.8 Ų66.852%0.51733%0.334SS..Hα-helixtrans-67.2-44.3171.7-1690000110.9N98 Y99 L100 L104 K105N98-S102 PolarHBondContact O-N 3.06Å; Y99-S102 PolarHBondContact O-N 3.41Å; L100-S102 VanDerWaalsContact C-N 3.32Å; S102-L104 VanDerWaalsContact C-N 3.33Å; S102-L104 PolarHBondContact O-N 2.69Å; S102-K105 WeakPolarHBondContact O-CB 3.46Å; S102-K105 PolarHBondContact O-N 2.95Å
103L88.9Confident87.8Confident14 Ų1469.8 Ų69.87%0.07335%0.348CS..Hα-helixtrans-65.1-35.3-178.8-172.964.3000112.8Y99 L100 K105 D106 F118 Q122 L171Y99-L103 HydrophobicContact CE1-CD2 4.16Å; Y99-L103 WeakPolarHBondContact O-CB 3.37Å; Y99-L103 PolarHBondContact O-N 3.3Å; L100-L103 HydrophobicContact CD2-CD2 4.28Å; L100-L103 PolarHBondContact O-N 2.93Å; L103-K105 PolarHBondContact O-N 3.47Å; L103-D106 PolarHBondContact O-N 3.43Å; L103-D106 VanDerWaalsContact O-N 3.15Å; L103-F118 HydrophobicContact CD1-CE2 4.32Å; L103-F118 HydrophobicContact CD1-CZ 4.08Å; L103-F118 HydrophobicContact CG-CZ 4.14Å; L103-F118 WeakPolarHBondContact O-CZ 3.31Å; L103-Q122 HydrophobicContact CD1-CG 4.07Å; L103-Q122 HydrophobicContact CD2-CB 4.1Å; L103-Q122 HydrophobicContact CD2-CG 4.1Å; L103-Q122 HydrophobicContact CG-CG 4.38Å; L103-L171 HydrophobicContact CD2-CD2 4.47Å; L103-L171 HydrophobicContact CG-CD1 4.43Å
104L88.6Confident87.9Confident19 Ų1968.6 Ų68.610%0.09935%0.351CS..Hα-helixtrans-56.5-39.5177.5-179.264.6000112L100 S102 D106 G107 E108 L171 P174 L175L100-L104 WeakPolarHBondContact O-CB 3.4Å; L100-L104 PolarHBondContact O-N 2.81Å; S102-L104 VanDerWaalsContact C-N 3.33Å; S102-L104 PolarHBondContact O-N 2.69Å; L104-D106 PolarHBondContact O-N 3.04Å; L104-G107 PolarHBondContact O-N 3.41Å; L104-E108 HydrophobicContact CD1-CG 4.18Å; L104-E108 WeakPolarHBondContact CD2-OE1 3.14Å; L104-E108 HydrophobicContact CG-CG 3.94Å; L104-E108 PolarHBondContact O-N 2.99Å; L104-L171 HydrophobicContact CB-CD1 3.89Å; L104-L171 HydrophobicContact CD1-CD1 4.01Å; L104-P174 HydrophobicContact CD1-CB 3.84Å; L104-P174 HydrophobicContact CD1-CG 4.31Å; L104-P174 HydrophobicContact CD2-CB 4.06Å; L104-P174 HydrophobicContact CD2-CG 3.97Å; L104-L175 HydrophobicContact CD1-CD1 3.98Å; L104-L175 HydrophobicContact CD1-CD2 3.99Å; L104-L175 HydrophobicContact CD1-CG 3.72Å
105K88.3Confident88Confident148 Ų14863.2 Ų63.264%0.64333%0.326SS*.Hα-helixtrans-60.3-30-179.9-64.7-178.8178.6-177.40113.1S102 L103 G107S102-K105 WeakPolarHBondContact O-CB 3.46Å; S102-K105 PolarHBondContact O-N 2.95Å; L103-K105 PolarHBondContact O-N 3.47Å; K105-G107 PolarHBondContact O-N 3.32Å
106D84.7Confident88Confident110 Ų11062.3 Ų62.359%0.58832%0.322SS*.THydrogen-bonded Turntrans-77.3-12.6178.8-58.6-29.7000112.2L103 L104 F118L103-D106 PolarHBondContact O-N 3.43Å; L103-D106 VanDerWaalsContact O-N 3.15Å; L104-D106 PolarHBondContact O-N 3.04Å; D106-F118 HydrophobicContact CB-CE2 4.08Å; D106-F118 HydrophobicContact CB-CZ 4.26Å
107G81.1Confident88.1Confident0 Ų067.1 Ų67.10%034%0.343CS..THydrogen-bonded Turntrans-118-12.5-175.100000116.3L104 K105 D109 L110L104-G107 PolarHBondContact O-N 3.41Å; K105-G107 PolarHBondContact O-N 3.32Å; G107-D109 VanDerWaalsContact C-N 3.3Å; G107-D109 PolarHBondContact O-N 3.11Å; G107-L110 PolarHBondContact O-N 3.12Å
108E83.3Confident88.2Confident97 Ų9763 Ų6345%0.45333%0.325SS..THydrogen-bonded Turntrans-59.2-35.3-173.2-88.6175.1-178.100114.2L104 Q178L104-E108 HydrophobicContact CD1-CG 4.18Å; L104-E108 WeakPolarHBondContact CD2-OE1 3.14Å; L104-E108 HydrophobicContact CG-CG 3.94Å; L104-E108 PolarHBondContact O-N 2.99Å; E108-Q178 PolarHBondContact O-NE2 3.36Å
109D86.1Confident88.3Confident155 Ų15558.9 Ų58.983%0.82930%0.303SS*.THydrogen-bonded Turntrans-94.7-2.1-177.7-65.7-38.7000113.6G107G107-D109 VanDerWaalsContact C-N 3.3Å; G107-D109 PolarHBondContact O-N 3.11Å
110L88.6Confident88.3Confident54 Ų5456.8 Ų56.828%0.28330%0.296SS..  trans-78.2141-179.1-63.1-179.9000111G107 C114 V115 F118G107-L110 PolarHBondContact O-N 3.12Å; L110-C114 HydrophobicContact CD2-CB 4.41Å; L110-V115 HydrophobicContact CB-CB 3.9Å; L110-V115 HydrophobicContact CB-CG2 4.25Å; L110-F118 HydrophobicContact CD1-CB 3.54Å; L110-F118 HydrophobicContact CD1-CD1 4.2Å; L110-F118 HydrophobicContact CD1-CD2 4.02Å; L110-F118 HydrophobicContact CD1-CG 3.66Å
111M85.7Confident88.4Confident98 Ų9861 Ų6148%0.48332%0.316SS..  trans-132.4163179.9-69.3-64.5-75.900112E113 C114 V115 Q178M111-E113 PolarHBondContact O-N 3.33Å; M111-C114 WeakPolarHBondContact O-CB 3.38Å; M111-C114 PolarHBondContact O-N 3.37Å; M111-V115 PolarHBondContact O-N 3.14Å; M111-Q178 HydrophobicContact SD-CB 4.43Å; M111-Q178 HydrophobicContact SD-CG 4.09Å
112D85.9Confident88.5Confident74 Ų7459.8 Ų59.840%0.39631%0.306SS..Hα-helixtrans49.7-131.6175.7-57.3-54.6000113.4C114 V115 L116 A182 K185D112-C114 PolarHBondContact O-N 3.36Å; D112-V115 WeakPolarHBondContact O-CG1 3.39Å; D112-V115 PolarHBondContact O-N 3.42Å; D112-L116 PolarHBondContact O-N 2.93Å; D112-A182 WeakPolarHBondContact O-CB 3.29Å; D112-K185 WeakPolarHBondContact OD1-CD 3.49Å; D112-K185 IonicContact OD1-NZ 2.62Å; D112-K185 PolarHBondContact OD1-NZ 2.88Å
113E87.4Confident88.6Confident63 Ų6356.4 Ų56.429%0.29428%0.282SS..Hα-helixtrans-66.3-25.3-174.8-158.8-175.514200113.2M111 L116 K117 L200M111-E113 PolarHBondContact O-N 3.33Å; E113-L116 PolarHBondContact O-N 2.77Å; E113-K117 WeakPolarHBondContact O-CG 3.43Å; E113-K117 PolarHBondContact O-N 2.88Å; E113-K117 WeakPolarHBondContact OE1-CE 3.04Å; E113-K117 IonicContact OE1-NZ 2.74Å; E113-K117 PolarHBondContact OE1-NZ 2.92Å; E113-L200 HydrophobicContact CG-CD1 3.73Å
114C88.3Confident88.7Confident77 Ų7761.2 Ų61.252%0.5230%0.304SS..Hα-helixtrans-66.9-42.5177.7-65.50000111.4L110 M111 D112 L116 K117 F118L110-C114 HydrophobicContact CD2-CB 4.41Å; M111-C114 WeakPolarHBondContact O-CB 3.38Å; M111-C114 PolarHBondContact O-N 3.37Å; D112-C114 PolarHBondContact O-N 3.36Å; C114-L116 VanDerWaalsContact C-N 3.29Å; C114-L116 PolarHBondContact O-N 3.4Å; C114-K117 PolarHBondContact O-N 2.88Å; C114-F118 WeakPolarHBondContact O-CB 3.08Å; C114-F118 PolarHBondContact O-N 2.86Å
115V91.1Very high88.8Confident0 Ų061.4 Ų61.40%031%0.305CS..Hα-helixtrans-66.8-33.5176.272.10000111.4L110 M111 D112 Y119 V179 A182L110-V115 HydrophobicContact CB-CB 3.9Å; L110-V115 HydrophobicContact CB-CG2 4.25Å; M111-V115 PolarHBondContact O-N 3.14Å; D112-V115 WeakPolarHBondContact O-CG1 3.39Å; D112-V115 PolarHBondContact O-N 3.42Å; V115-Y119 WeakPolarHBondContact O-CB 3.49Å; V115-Y119 PolarHBondContact O-N 3.33Å; V115-V179 HydrophobicContact CG2-CG2 3.97Å; V115-A182 HydrophobicContact CG1-CB 3.97Å
116L90.7Very high89Confident0 Ų054.5 Ų54.50%028%0.275CS..Hα-helixtrans-67.8-45.5176.2-62.7179.3000112.4D112 E113 C114 F118 Y119 T120 V179 A182 V183 L186 L200 V204D112-L116 PolarHBondContact O-N 2.93Å; E113-L116 PolarHBondContact O-N 2.77Å; C114-L116 VanDerWaalsContact C-N 3.29Å; C114-L116 PolarHBondContact O-N 3.4Å; L116-F118 VanDerWaalsContact C-N 3.34Å; L116-Y119 PolarHBondContact O-N 2.87Å; L116-T120 WeakPolarHBondContact O-CB 3.44Å; L116-T120 WeakPolarHBondContact O-CG2 3.48Å; L116-T120 PolarHBondContact O-N 3.46Å; L116-T120 PolarHBondContact O-OG1 3.12Å; L116-V179 HydrophobicContact CD2-CG1 3.98Å; L116-A182 HydrophobicContact CD1-CB 3.89Å; L116-A182 HydrophobicContact CD2-CB 3.86Å; L116-A182 HydrophobicContact CG-CB 3.71Å; L116-V183 HydrophobicContact CD1-CG2 4.39Å; L116-V183 HydrophobicContact CD2-CG2 3.57Å; L116-L186 HydrophobicContact CD1-CD1 3.32Å; L116-L186 HydrophobicContact CD1-CG 4.09Å; L116-L200 HydrophobicContact CB-CB 4.39Å; L116-L200 HydrophobicContact CB-CD1 4.37Å; L116-V204 HydrophobicContact CD2-CG2 3.98Å
117K91.8Very high89.3Confident103 Ų10352.4 Ų52.445%0.44826%0.259SS..Hα-helixtrans-60.9-44.9175.7-76.5172.6-177.8160.10111.3E113 C114 T120 Q121 L200E113-K117 WeakPolarHBondContact O-CG 3.43Å; E113-K117 PolarHBondContact O-N 2.88Å; E113-K117 WeakPolarHBondContact OE1-CE 3.04Å; E113-K117 IonicContact OE1-NZ 2.74Å; E113-K117 PolarHBondContact OE1-NZ 2.92Å; C114-K117 PolarHBondContact O-N 2.88Å; K117-T120 PolarHBondContact O-OG1 2.98Å; K117-Q121 WeakPolarHBondContact O-CB 3.42Å; K117-Q121 PolarHBondContact O-N 3.06Å; K117-Q121 VanDerWaalsContact O-N 3.09Å; K117-L200 HydrophobicContact CG-CD1 4.08Å; K117-L200 HydrophobicContact CG-CD2 3.87Å
118F92.4Very high89.7Confident30 Ų3058.4 Ų58.413%0.13229%0.286CS..Hα-helixtrans-60-55.9175.1174.8-98.6000111L103 D106 L110 C114 L116 T120 Q121 Q122 L175L103-F118 HydrophobicContact CD1-CE2 4.32Å; L103-F118 HydrophobicContact CD1-CZ 4.08Å; L103-F118 HydrophobicContact CG-CZ 4.14Å; L103-F118 WeakPolarHBondContact O-CZ 3.31Å; D106-F118 HydrophobicContact CB-CE2 4.08Å; D106-F118 HydrophobicContact CB-CZ 4.26Å; L110-F118 HydrophobicContact CD1-CB 3.54Å; L110-F118 HydrophobicContact CD1-CD1 4.2Å; L110-F118 HydrophobicContact CD1-CD2 4.02Å; L110-F118 HydrophobicContact CD1-CG 3.66Å; C114-F118 WeakPolarHBondContact O-CB 3.08Å; C114-F118 PolarHBondContact O-N 2.86Å; L116-F118 VanDerWaalsContact C-N 3.34Å; F118-T120 PolarHBondContact O-N 3.2Å; F118-Q121 PolarHBondContact O-N 3.38Å; F118-Q122 HydrophobicContact CD1-CG 4.47Å; F118-Q122 HydrophobicContact CD2-CG 3.99Å; F118-Q122 HydrophobicContact CE1-CG 4.23Å; F118-Q122 HydrophobicContact CE2-CG 3.73Å; F118-Q122 HydrophobicContact CG-CG 4.36Å; F118-Q122 HydrophobicContact CZ-CG 3.86Å; F118-Q122 WeakPolarHBondContact O-CB 3.44Å; F118-Q122 WeakPolarHBondContact O-CG 3.35Å; F118-Q122 PolarHBondContact O-N 2.95Å; F118-L175 HydrophobicContact CE1-CD1 4.4Å
119Y92.4Very high90Very high0 Ų053.9 Ų53.90%026%0.264CS..Hα-helixtrans-60.7-44.2-175.9-175.4-88.9000112.5V115 L116 W123 W167 L171 V179 V204 S207 Y208V115-Y119 WeakPolarHBondContact O-CB 3.49Å; V115-Y119 PolarHBondContact O-N 3.33Å; L116-Y119 PolarHBondContact O-N 2.87Å; Y119-W123 WeakPolarHBondContact O-CB 3.33Å; Y119-W123 PolarHBondContact O-N 3.37Å; Y119-W167 HydrophobicContact CD2-CZ2 4.18Å; Y119-W167 HydrophobicContact CE1-CZ2 4.46Å; Y119-W167 AromaticContact CE2-CZ2 3.72Å; Y119-W167 HydrophobicContact CE2-CZ2 3.72Å; Y119-W167 AromaticContact CE2-NE1 3.83Å; Y119-W167 AromaticContact CZ-CZ2 3.87Å; Y119-W167 AromaticContact CZ-NE1 3.62Å; Y119-W167 PolarHBondContact OH-NE1 2.95Å; Y119-L171 HydrophobicContact CD2-CD2 4.46Å; Y119-L171 HydrophobicContact CE2-CD2 4.49Å; Y119-V179 HydrophobicContact CD1-CG1 4.29Å; Y119-V179 HydrophobicContact CD2-CG2 3.99Å; Y119-V179 HydrophobicContact CG-CG1 4.38Å; Y119-V179 HydrophobicContact CG-CG2 4.04Å; Y119-V204 HydrophobicContact CD1-CG2 4.04Å; Y119-S207 PolarHBondContact OH-OG 3.41Å; Y119-Y208 HydrophobicContact CE1-CE1 4.4Å
120T91.2Very high90.2Very high13 Ų1346.5 Ų46.58%0.0823%0.225CC..Hα-helixtrans-68-45-179.750.40000112.5L116 K117 F118 W123 E124 L200 V204L116-T120 WeakPolarHBondContact O-CB 3.44Å; L116-T120 WeakPolarHBondContact O-CG2 3.48Å; L116-T120 PolarHBondContact O-N 3.46Å; L116-T120 PolarHBondContact O-OG1 3.12Å; K117-T120 PolarHBondContact O-OG1 2.98Å; F118-T120 PolarHBondContact O-N 3.2Å; T120-W123 PolarHBondContact O-N 3.35Å; T120-E124 WeakPolarHBondContact O-CG 3.34Å; T120-E124 PolarHBondContact O-N 2.92Å; T120-L200 HydrophobicContact CG2-CD2 4.49Å; T120-L200 WeakPolarHBondContact CG2-O 3.07Å; T120-V204 HydrophobicContact CG2-CG2 3.78Å
121Q91.1Very high90.2Very high89 Ų8948.4 Ų48.442%0.41623%0.231SC..Hα-helixtrans-60.9-49.1176-177.662.145.900111K117 F118 W123 E124 D125K117-Q121 WeakPolarHBondContact O-CB 3.42Å; K117-Q121 PolarHBondContact O-N 3.06Å; K117-Q121 VanDerWaalsContact O-N 3.09Å; F118-Q121 PolarHBondContact O-N 3.38Å; Q121-W123 VanDerWaalsContact C-N 3.28Å; Q121-W123 PolarHBondContact O-N 3.41Å; Q121-E124 PolarHBondContact O-N 3.48Å; Q121-D125 PolarHBondContact NE2-OD1 3.28Å; Q121-D125 PolarHBondContact NE2-OD2 3.27Å; Q121-D125 WeakPolarHBondContact O-CB 3.4Å; Q121-D125 PolarHBondContact O-N 3.2Å
122Q91.3Very high90.4Very high38 Ų3845.5 Ų45.518%0.17822%0.219CC..Hα-helixtrans-64.3-35.7179.2-67.5-49.7-40.600111.8L103 F118 Y126 W167L103-Q122 HydrophobicContact CD1-CG 4.07Å; L103-Q122 HydrophobicContact CD2-CB 4.1Å; L103-Q122 HydrophobicContact CD2-CG 4.1Å; L103-Q122 HydrophobicContact CG-CG 4.38Å; F118-Q122 HydrophobicContact CD1-CG 4.47Å; F118-Q122 HydrophobicContact CD2-CG 3.99Å; F118-Q122 HydrophobicContact CE1-CG 4.23Å; F118-Q122 HydrophobicContact CE2-CG 3.73Å; F118-Q122 HydrophobicContact CG-CG 4.36Å; F118-Q122 HydrophobicContact CZ-CG 3.86Å; F118-Q122 WeakPolarHBondContact O-CB 3.44Å; F118-Q122 WeakPolarHBondContact O-CG 3.35Å; F118-Q122 PolarHBondContact O-N 2.95Å; Q122-Y126 WeakPolarHBondContact O-CB 3.12Å; Q122-Y126 PolarHBondContact O-N 2.71Å; Q122-W167 HydrophobicContact CB-CH2 3.92Å
123W92.6Very high90.5Very high3 Ų342 Ų421%0.01120%0.2CC..Hα-helixtrans-65.1-47.1175.7173.1-114.3000111.9Y119 T120 Q121 D125 Y126 R127 L164 W167 E210 L211Y119-W123 WeakPolarHBondContact O-CB 3.33Å; Y119-W123 PolarHBondContact O-N 3.37Å; T120-W123 PolarHBondContact O-N 3.35Å; Q121-W123 VanDerWaalsContact C-N 3.28Å; Q121-W123 PolarHBondContact O-N 3.41Å; W123-D125 VanDerWaalsContact C-N 3.35Å; W123-D125 PolarHBondContact O-N 3.36Å; W123-Y126 PolarHBondContact O-N 3.46Å; W123-R127 WeakPolarHBondContact O-CB 3.45Å; W123-R127 PolarHBondContact O-N 3.34Å; W123-L164 HydrophobicContact CH2-CD2 3.46Å; W123-L164 VanDerWaalsContact CH2-CD2 3.46Å; W123-L164 HydrophobicContact CZ2-CD2 4.37Å; W123-L164 HydrophobicContact CZ3-CD2 4.1Å; W123-W167 VanDerWaalsContact CA-CH2 3.46Å; W123-W167 HydrophobicContact CB-CH2 3.99Å; W123-W167 HydrophobicContact CB-CZ2 3.78Å; W123-W167 HydrophobicContact CD2-CZ2 4.36Å; W123-W167 AromaticContact CE3-CD1 3.97Å; W123-W167 AromaticContact CE3-CD2 3.64Å; W123-W167 HydrophobicContact CE3-CD2 3.64Å; W123-W167 AromaticContact CE3-CE2 3.36Å; W123-W167 HydrophobicContact CE3-CE3 4.19Å; W123-W167 HydrophobicContact CE3-CG 4.01Å; W123-W167 HydrophobicContact CE3-CH2 4.22Å; W123-W167 AromaticContact CE3-CZ2 3.66Å; W123-W167 HydrophobicContact CE3-CZ2 3.66Å; W123-W167 HydrophobicContact CE3-CZ3 4.47Å; W123-W167 AromaticContact CE3-NE1 3.57Å; W123-W167 HydrophobicContact CG-CZ2 4.46Å; W123-W167 HydrophobicContact CZ3-CB 4.35Å; W123-W167 AromaticContact CZ3-CD1 3.63Å; W123-W167 AromaticContact CZ3-CD2 3.82Å; W123-W167 HydrophobicContact CZ3-CD2 3.82Å; W123-W167 AromaticContact CZ3-CE2 3.85Å; W123-W167 AromaticContact CZ3-CG 3.68Å; W123-W167 HydrophobicContact CZ3-CG 3.68Å; W123-W167 AromaticContact CZ3-NE1 3.72Å; W123-E210 HydrophobicContact CH2-CB 4.45Å; W123-E210 HydrophobicContact CZ2-CB 3.96Å; W123-L211 HydrophobicContact CH2-CD2 3.95Å; W123-L211 HydrophobicContact CH2-CG 4.06Å; W123-L211 HydrophobicContact CZ3-CD2 4.03Å; W123-L211 HydrophobicContact CZ3-CG 4.38Å
124E90.6Very high90.5Very high114 Ų11440.4 Ų40.453%0.53319%0.193SC..Hα-helixtrans-60.3-46.2177.6-74.5-174.2177.700111.6T120 Q121 F128T120-E124 WeakPolarHBondContact O-CG 3.34Å; T120-E124 PolarHBondContact O-N 2.92Å; Q121-E124 PolarHBondContact O-N 3.48Å; E124-F128 WeakPolarHBondContact O-CB 3.47Å; E124-F128 PolarHBondContact O-N 2.82Å
125D91Very high90.4Very high24 Ų2437.7 Ų37.713%0.12818%0.178CC..Hα-helixtrans-66.4-44.1-179.9-71.7-26.9000111.8R34 Q121 W123 S129R34-D125 VanDerWaalsContact CD-OD1 3.27Å; R34-D125 WeakPolarHBondContact CD-OD1 3.47Å; R34-D125 IonicContact CZ-OD1 3.4Å; R34-D125 IonicContact NE-OD1 3.51Å; R34-D125 IonicContact NH1-OD1 2.73Å; R34-D125 PolarHBondContact NH1-OD1 3.09Å; Q121-D125 PolarHBondContact NE2-OD1 3.28Å; Q121-D125 PolarHBondContact NE2-OD2 3.27Å; Q121-D125 WeakPolarHBondContact O-CB 3.4Å; Q121-D125 PolarHBondContact O-N 3.2Å; W123-D125 VanDerWaalsContact C-N 3.35Å; W123-D125 PolarHBondContact O-N 3.36Å; D125-S129 VanDerWaalsContact O-CB 3.26Å; D125-S129 WeakPolarHBondContact O-CB 3.36Å; D125-S129 PolarHBondContact O-N 3.47Å; D125-S129 PolarHBondContact O-OG 2.91Å
126Y91.7Very high90.2Very high3 Ų337.7 Ų37.71%0.01218%0.178CC..Hα-helixtrans-65-48.6176.6-173.3-96.7000111.1Y32 L96 Y99 L100 Q122 W123 F128 S129 S130 A163 W167Y32-Y126 HydrophobicContact CD1-CD2 4.07Å; Y32-Y126 HydrophobicContact CD1-CE2 4.25Å; Y32-Y126 AromaticContact CE1-CD2 3.5Å; Y32-Y126 HydrophobicContact CE1-CD2 3.5Å; Y32-Y126 AromaticContact CE1-CE2 3.45Å; Y32-Y126 HydrophobicContact CE1-CE2 3.45Å; Y32-Y126 VanDerWaalsContact CE1-CE2 3.45Å; Y32-Y126 HydrophobicContact CE1-CG 4.39Å; L96-Y126 HydrophobicContact CD2-CE2 4.42Å; Y99-Y126 HydrophobicContact CD1-CD2 4.22Å; Y99-Y126 HydrophobicContact CD1-CE2 4.17Å; Y99-Y126 AromaticContact CE1-CD2 3.98Å; Y99-Y126 HydrophobicContact CE1-CD2 3.98Å; Y99-Y126 HydrophobicContact CE1-CE2 4.39Å; L100-Y126 HydrophobicContact CD1-CE2 3.91Å; L100-Y126 WeakPolarHBondContact CD1-OH 3.2Å; L100-Y126 HydrophobicContact CD2-CD2 3.8Å; L100-Y126 HydrophobicContact CD2-CE2 3.59Å; L100-Y126 HydrophobicContact CG-CD2 4.49Å; L100-Y126 HydrophobicContact CG-CE2 3.8Å; Q122-Y126 WeakPolarHBondContact O-CB 3.12Å; Q122-Y126 PolarHBondContact O-N 2.71Å; W123-Y126 PolarHBondContact O-N 3.46Å; Y126-F128 VanDerWaalsContact C-N 3.34Å; Y126-F128 PolarHBondContact O-N 2.94Å; Y126-S129 PolarHBondContact O-N 3.07Å; Y126-S130 WeakPolarHBondContact CE1-OG 3.3Å; Y126-S130 WeakPolarHBondContact O-CB 3.29Å; Y126-S130 PolarHBondContact O-N 2.98Å; Y126-S130 PolarHBondContact O-OG 3.38Å; Y126-A163 HydrophobicContact CE1-CB 3.95Å; Y126-A163 WeakPolarHBondContact CE1-O 3.42Å; Y126-A163 WeakPolarHBondContact OH-CA 3.3Å; Y126-A163 PolarHBondContact OH-O 2.67Å; Y126-W167 VanDerWaalsContact CB-CZ3 3.48Å; Y126-W167 HydrophobicContact CD1-CB 4.39Å; Y126-W167 HydrophobicContact CD1-CD2 4.16Å; Y126-W167 AromaticContact CD1-CE3 3.38Å; Y126-W167 HydrophobicContact CD1-CE3 3.38Å; Y126-W167 HydrophobicContact CD1-CZ3 4Å; Y126-W167 HydrophobicContact CD2-CE3 4.03Å; Y126-W167 HydrophobicContact CD2-CZ3 4.2Å; Y126-W167 HydrophobicContact CE1-CB 3.92Å; Y126-W167 AromaticContact CE1-CE3 3.9Å; Y126-W167 HydrophobicContact CE1-CE3 3.9Å; Y126-W167 HydrophobicContact CE2-CE3 4.48Å; Y126-W167 AromaticContact CG-CE3 3.47Å; Y126-W167 HydrophobicContact CG-CE3 3.47Å; Y126-W167 VanDerWaalsContact CG-CE3 3.47Å; Y126-W167 AromaticContact CG-CZ3 3.64Å; Y126-W167 HydrophobicContact CG-CZ3 3.64Å
127R90.4Very high90.1Very high66 Ų6637.7 Ų37.725%0.24918%0.178CC..Hα-helixtrans-57.7-44.8178.8-178.7-177.6180-113.69.3111.9W123 K131 E210W123-R127 WeakPolarHBondContact O-CB 3.45Å; W123-R127 PolarHBondContact O-N 3.34Å; R127-K131 VanDerWaalsContact CZ-NZ 3.27Å; R127-K131 VanDerWaalsContact NH2-NZ 3.18Å; R127-K131 WeakPolarHBondContact O-CG 3.21Å; R127-K131 PolarHBondContact O-N 2.87Å; R127-K131 VanDerWaalsContact O-N 3.14Å; R127-E210 IonicContact CZ-OE1 3.65Å; R127-E210 IonicContact CZ-OE2 3.21Å; R127-E210 VanDerWaalsContact NE-CD 3.31Å; R127-E210 IonicContact NE-OE1 3.88Å; R127-E210 PolarHBondContact NE-OE1 3.28Å; R127-E210 IonicContact NE-OE2 3.08Å; R127-E210 PolarHBondContact NE-OE2 3.4Å; R127-E210 IonicContact NH2-OE1 2.67Å; R127-E210 PolarHBondContact NH2-OE1 3.2Å; R127-E210 IonicContact NH2-OE2 3.31Å
128F89.5Confident89.8Confident126 Ų12634.7 Ų34.755%0.55317%0.173SC*.Hα-helixtrans-62.3-51.4175.1177.7-95.5000111.1E124 Y126 S130 K131 V132E124-F128 WeakPolarHBondContact O-CB 3.47Å; E124-F128 PolarHBondContact O-N 2.82Å; Y126-F128 VanDerWaalsContact C-N 3.34Å; Y126-F128 PolarHBondContact O-N 2.94Å; F128-S130 VanDerWaalsContact C-N 3.29Å; F128-S130 PolarHBondContact O-N 2.94Å; F128-K131 PolarHBondContact O-N 2.86Å; F128-K131 VanDerWaalsContact O-N 3.12Å; F128-V132 HydrophobicContact CD1-CG2 4.36Å; F128-V132 HydrophobicContact CE1-CG2 3.93Å; F128-V132 HydrophobicContact CZ-CG2 4.05Å; F128-V132 PolarHBondContact O-N 3.23Å; F128-V132 VanDerWaalsContact O-N 3.11Å
129S91.1Very high89.4Confident1 Ų135.5 Ų35.51%0.00718%0.175CC..Hα-helixtrans-59.4-39.1-179.5-59.20000112.2V31 D125 Y126 V132 L133V31-S129 PolarHBondContact O-OG 3.44Å; D125-S129 VanDerWaalsContact O-CB 3.26Å; D125-S129 WeakPolarHBondContact O-CB 3.36Å; D125-S129 PolarHBondContact O-N 3.47Å; D125-S129 PolarHBondContact O-OG 2.91Å; Y126-S129 PolarHBondContact O-N 3.07Å; S129-V132 PolarHBondContact O-N 3.3Å; S129-L133 WeakPolarHBondContact O-CB 3.46Å; S129-L133 PolarHBondContact O-N 3.2Å
130S90.3Very high88.9Confident1 Ų135.5 Ų35.51%0.00718%0.176CC..Hα-helixtrans-69-33.7176.9-600000113.1Y32 Y126 F128 L133 N134 A163Y32-S130 WeakPolarHBondContact OH-CA 3.48Å; Y32-S130 PolarHBondContact OH-OG 3.3Å; Y126-S130 WeakPolarHBondContact CE1-OG 3.3Å; Y126-S130 WeakPolarHBondContact O-CB 3.29Å; Y126-S130 PolarHBondContact O-N 2.98Å; Y126-S130 PolarHBondContact O-OG 3.38Å; F128-S130 VanDerWaalsContact C-N 3.29Å; F128-S130 PolarHBondContact O-N 2.94Å; S130-L133 PolarHBondContact O-N 3.28Å; S130-N134 WeakPolarHBondContact O-CB 3.47Å; S130-N134 PolarHBondContact O-N 3.25Å; S130-A163 VanDerWaalsContact OG-CB 3.31Å; S130-A163 WeakPolarHBondContact OG-CB 3.4Å
131K88.7Confident88.6Confident94 Ų9435.6 Ų35.641%0.40918%0.176SC..Hα-helixtrans-66.8-41.3172.2-73.8179.3-177.5179.70111.7R127 F128 N134 G135 Y160R127-K131 VanDerWaalsContact CZ-NZ 3.27Å; R127-K131 VanDerWaalsContact NH2-NZ 3.18Å; R127-K131 WeakPolarHBondContact O-CG 3.21Å; R127-K131 PolarHBondContact O-N 2.87Å; R127-K131 VanDerWaalsContact O-N 3.14Å; F128-K131 PolarHBondContact O-N 2.86Å; F128-K131 VanDerWaalsContact O-N 3.12Å; K131-N134 WeakPolarHBondContact O-CB 3.36Å; K131-N134 PolarHBondContact O-N 2.97Å; K131-G135 PolarHBondContact O-N 3.25Å; K131-Y160 HydrophobicContact CD-CE2 4.39Å; K131-Y160 WeakPolarHBondContact CE-OH 3.45Å; K131-Y160 HydrophobicContact CG-CD2 3.87Å; K131-Y160 HydrophobicContact CG-CE2 3.47Å; K131-Y160 VanDerWaalsContact CG-CE2 3.47Å
132V88.1Confident88.2Confident36 Ų3639.9 Ų39.922%0.21819%0.188CC..Hα-helixtrans-63.1-45.5174.7178.30000110.2V31 Y42 F128 S129 N134 G135 I136V31-V132 HydrophobicContact CG1-CB 3.87Å; V31-V132 HydrophobicContact CG1-CG1 3.84Å; V31-V132 HydrophobicContact CG2-CG1 4.04Å; Y42-V132 HydrophobicContact CD2-CG1 4.42Å; Y42-V132 HydrophobicContact CE2-CG1 4.12Å; F128-V132 HydrophobicContact CD1-CG2 4.36Å; F128-V132 HydrophobicContact CE1-CG2 3.93Å; F128-V132 HydrophobicContact CZ-CG2 4.05Å; F128-V132 PolarHBondContact O-N 3.23Å; F128-V132 VanDerWaalsContact O-N 3.11Å; S129-V132 PolarHBondContact O-N 3.3Å; V132-N134 VanDerWaalsContact C-N 3.33Å; V132-N134 PolarHBondContact O-N 3.49Å; V132-G135 PolarHBondContact O-N 2.78Å; V132-G135 VanDerWaalsContact O-N 3.12Å; V132-I136 HydrophobicContact CG1-CD1 4.23Å; V132-I136 WeakPolarHBondContact O-CG1 3.45Å; V132-I136 PolarHBondContact O-N 2.94Å
133L88.3Confident87.7Confident1 Ų142.5 Ų42.51%0.00520%0.2CC..Hα-helixtrans-58.8-43.1174.9-179.662.8000111.9I28 Y32 L92 L96 S129 S130 G135 I136 C137 I159I28-L133 HydrophobicContact CD1-CD1 3.87Å; I28-L133 HydrophobicContact CG1-CD1 3.73Å; I28-L133 HydrophobicContact CG2-CD1 4.05Å; Y32-L133 HydrophobicContact CE2-CB 4.3Å; Y32-L133 HydrophobicContact CE2-CD2 3.96Å; L92-L133 HydrophobicContact CD2-CD1 4.35Å; L96-L133 HydrophobicContact CD1-CD2 4.45Å; L96-L133 HydrophobicContact CD2-CD2 4.02Å; S129-L133 WeakPolarHBondContact O-CB 3.46Å; S129-L133 PolarHBondContact O-N 3.2Å; S130-L133 PolarHBondContact O-N 3.28Å; L133-G135 VanDerWaalsContact C-N 3.26Å; L133-G135 PolarHBondContact O-N 3.02Å; L133-I136 PolarHBondContact O-N 3.47Å; L133-C137 WeakPolarHBondContact O-CB 3.36Å; L133-C137 PolarHBondContact O-N 2.89Å; L133-I159 HydrophobicContact CD2-CG2 3.91Å; L133-I159 HydrophobicContact CG-CG2 3.79Å
134N87.7Confident87.2Confident29 Ų2943.2 Ų43.216%0.15520%0.203CC..Hα-helixtrans-59.4-38.9176.2-163.762.2000112S130 K131 V132 C137 A138 N141 E158 Y160S130-N134 WeakPolarHBondContact O-CB 3.47Å; S130-N134 PolarHBondContact O-N 3.25Å; K131-N134 WeakPolarHBondContact O-CB 3.36Å; K131-N134 PolarHBondContact O-N 2.97Å; V132-N134 VanDerWaalsContact C-N 3.33Å; V132-N134 PolarHBondContact O-N 3.49Å; N134-C137 CarbonylContact O-C 3.55Å; N134-C137 PolarHBondContact O-N 2.91Å; N134-A138 PolarHBondContact O-N 3.2Å; N134-A138 VanDerWaalsContact O-N 3.09Å; N134-N141 PolarHBondContact O-ND2 3.41Å; N134-N141 PolarHBondContact OD1-ND2 3.06Å; N134-E158 PolarHBondContact ND2-OE1 3.11Å; N134-E158 PolarHBondContact OD1-OE1 3.42Å; N134-Y160 PolarHBondContact OD1-N 2.95Å
135G86.4Confident86.7Confident20 Ų2038.1 Ų38.121%0.20618%0.179CC..Hα-helixtrans-65.4-44.3173.900000113.3Y42 K131 V132 L133 C137 A138Y42-G135 WeakPolarHBondContact OH-CA 3.21Å; Y42-G135 PolarHBondContact OH-O 2.95Å; K131-G135 PolarHBondContact O-N 3.25Å; V132-G135 PolarHBondContact O-N 2.78Å; V132-G135 VanDerWaalsContact O-N 3.12Å; L133-G135 VanDerWaalsContact C-N 3.26Å; L133-G135 PolarHBondContact O-N 3.02Å; G135-C137 PolarHBondContact O-N 3.16Å; G135-A138 VanDerWaalsContact O-CB 3.3Å; G135-A138 WeakPolarHBondContact O-CB 3.46Å; G135-A138 PolarHBondContact O-N 2.99Å
136I87.7Confident86Confident0 Ų043.7 Ų43.70%020%0.198CC..Hα-helixtrans-60-39.5175.1-65.9169.3000110.1L24 V31 Y42 L45 Y46 V49 V132 L133 A138L24-I136 HydrophobicContact CD1-CG2 4.3Å; V31-I136 HydrophobicContact CG2-CD1 4.12Å; Y42-I136 HydrophobicContact CD2-CD1 4.31Å; Y42-I136 HydrophobicContact CD2-CG1 3.85Å; Y42-I136 HydrophobicContact CE2-CD1 4.27Å; Y42-I136 HydrophobicContact CE2-CG1 3.48Å; Y42-I136 VanDerWaalsContact CE2-CG1 3.48Å; Y42-I136 PolarHBondContact OH-N 3.44Å; L45-I136 HydrophobicContact CB-CG2 3.87Å; L45-I136 HydrophobicContact CD1-CD1 4.13Å; Y46-I136 WeakPolarHBondContact CD2-O 3.22Å; V49-I136 HydrophobicContact CG2-CG2 4.05Å; V132-I136 HydrophobicContact CG1-CD1 4.23Å; V132-I136 WeakPolarHBondContact O-CG1 3.45Å; V132-I136 PolarHBondContact O-N 2.94Å; L133-I136 PolarHBondContact O-N 3.47Å; I136-A138 VanDerWaalsContact C-N 3.35Å; I136-A138 PolarHBondContact O-N 3.46Å
137C86.9Confident85.4Confident0 Ų050.7 Ų50.70%023%0.225CC..THydrogen-bonded Turntrans-89.714.4179.9-630000114.5L133 N134 G135 Y139 L140 N141 I159L133-C137 WeakPolarHBondContact O-CB 3.36Å; L133-C137 PolarHBondContact O-N 2.89Å; N134-C137 CarbonylContact O-C 3.55Å; N134-C137 PolarHBondContact O-N 2.91Å; G135-C137 PolarHBondContact O-N 3.16Å; C137-Y139 PolarHBondContact O-N 2.95Å; C137-Y139 VanDerWaalsContact O-N 3.14Å; C137-L140 HydrophobicContact CB-CB 4.43Å; C137-L140 WeakPolarHBondContact O-CA 3.44Å; C137-L140 WeakPolarHBondContact O-CB 3.42Å; C137-L140 PolarHBondContact O-N 3.35Å; C137-N141 PolarHBondContact O-N 3.01Å; C137-I159 HydrophobicContact CB-CB 4.32Å; C137-I159 HydrophobicContact CB-CG1 3.77Å; C137-I159 HydrophobicContact CB-CG2 4.4Å
138A85.9Confident84.7Confident40 Ų4047.6 Ų47.633%0.33121%0.213SC..Hα-helixtrans-61.1-30.4-173.400000113.6Y46 N134 G135 I136 R142Y46-A138 HydrophobicContact CE2-CB 4.19Å; N134-A138 PolarHBondContact O-N 3.2Å; N134-A138 VanDerWaalsContact O-N 3.09Å; G135-A138 VanDerWaalsContact O-CB 3.3Å; G135-A138 WeakPolarHBondContact O-CB 3.46Å; G135-A138 PolarHBondContact O-N 2.99Å; I136-A138 VanDerWaalsContact C-N 3.35Å; I136-A138 PolarHBondContact O-N 3.46Å; A138-R142 WeakPolarHBondContact O-CB 3.28Å; A138-R142 PolarHBondContact O-N 3.48Å
139Y83.8Confident83.9Confident47 Ų4742.9 Ų42.918%0.18420%0.195CC..Hα-helixtrans-65.9-43.7172.9-170.8-97000112.2Y50 C53 T54 C137 R142 H143Y50-Y139 AromaticContact CD2-CD1 3.99Å; Y50-Y139 HydrophobicContact CD2-CD1 3.99Å; Y50-Y139 AromaticContact CD2-CD2 3.57Å; Y50-Y139 HydrophobicContact CD2-CD2 3.57Å; Y50-Y139 AromaticContact CD2-CE1 3.86Å; Y50-Y139 HydrophobicContact CD2-CE1 3.86Å; Y50-Y139 AromaticContact CD2-CE2 3.42Å; Y50-Y139 HydrophobicContact CD2-CE2 3.42Å; Y50-Y139 VanDerWaalsContact CD2-CE2 3.42Å; Y50-Y139 AromaticContact CD2-CG 3.85Å; Y50-Y139 HydrophobicContact CD2-CG 3.85Å; Y50-Y139 AromaticContact CD2-CZ 3.57Å; Y50-Y139 HydrophobicContact CE2-CD2 4.08Å; Y50-Y139 HydrophobicContact CE2-CE1 4.26Å; Y50-Y139 AromaticContact CE2-CE2 3.47Å; Y50-Y139 HydrophobicContact CE2-CE2 3.47Å; Y50-Y139 VanDerWaalsContact CE2-CE2 3.47Å; Y50-Y139 AromaticContact CE2-CZ 3.57Å; C53-Y139 HydrophobicContact CB-CD1 3.84Å; C53-Y139 HydrophobicContact CB-CE1 3.75Å; T54-Y139 HydrophobicContact CG2-CE1 3.97Å; T54-Y139 WeakPolarHBondContact CG2-OH 3.23Å; C137-Y139 PolarHBondContact O-N 2.95Å; C137-Y139 VanDerWaalsContact O-N 3.14Å; Y139-R142 PolarHBondContact O-N 3.17Å; Y139-H143 AromaticContact CD2-CD2 3.45Å; Y139-H143 VanDerWaalsContact CD2-CD2 3.45Å; Y139-H143 WeakPolarHBondContact CD2-CD2 3.45Å; Y139-H143 AromaticContact CD2-NE2 3.83Å; Y139-H143 AromaticContact CE2-CD2 3.26Å; Y139-H143 WeakPolarHBondContact CE2-CD2 3.37Å; Y139-H143 AromaticContact CE2-NE2 3.45Å; Y139-H143 WeakPolarHBondContact CE2-NE2 3.37Å; Y139-H143 AromaticContact CG-CD2 4Å; Y139-H143 AromaticContact CZ-CD2 3.66Å; Y139-H143 PolarHBondContact O-CD2 3.43Å; Y139-H143 PolarHBondContact O-N 2.96Å; Y139-H143 VanDerWaalsContact O-N 3.1Å
140L83.4Confident83Confident1 Ų148.1 Ų48.11%0.00522%0.223CC..Hα-helixtrans-62-43.8175.9-17771.7000110.7V49 L88 L92 C137 W144 V145 I159V49-L140 HydrophobicContact CG1-CB 4.09Å; L88-L140 HydrophobicContact CD2-CD1 4.41Å; L88-L140 HydrophobicContact CD2-CD2 4.22Å; L88-L140 HydrophobicContact CG-CD2 4.41Å; L92-L140 HydrophobicContact CD1-CD2 3.97Å; C137-L140 HydrophobicContact CB-CB 4.43Å; C137-L140 WeakPolarHBondContact O-CA 3.44Å; C137-L140 WeakPolarHBondContact O-CB 3.42Å; C137-L140 PolarHBondContact O-N 3.35Å; L140-W144 HydrophobicContact CD1-CB 3.8Å; L140-W144 HydrophobicContact CD1-CD2 4.2Å; L140-W144 HydrophobicContact CD1-CE3 4.01Å; L140-W144 HydrophobicContact CD1-CG 4.13Å; L140-W144 HydrophobicContact CG-CE3 4.41Å; L140-W144 PolarHBondContact O-N 3.17Å; L140-V145 HydrophobicContact CG-CG2 4.41Å; L140-V145 PolarHBondContact O-N 3.08Å; L140-I159 HydrophobicContact CD2-CD1 4.17Å; L140-I159 HydrophobicContact CD2-CG1 4.44Å
141N84.8Confident82.2Confident15 Ų1552.5 Ų52.58%0.0824%0.244CC..Iπ-helixtrans-59.2-48.8175.7-74.8-25000112.2N134 C137 R146 E158 I159N134-N141 PolarHBondContact O-ND2 3.41Å; N134-N141 PolarHBondContact OD1-ND2 3.06Å; C137-N141 PolarHBondContact O-N 3.01Å; N141-R146 PolarHBondContact O-N 2.76Å; N141-E158 HydrophobicContact CB-CG 4.08Å; N141-E158 WeakPolarHBondContact ND2-CG 3.48Å; N141-E158 PolarHBondContact ND2-OE1 2.92Å; N141-E158 WeakPolarHBondContact OD1-CG 3.32Å; N141-I159 WeakPolarHBondContact OD1-CG1 3.46Å; N141-I159 PolarHBondContact OD1-N 3.08Å; N141-I159 VanDerWaalsContact OD1-N 3.08Å
142R82.7Confident81Confident178 Ų17850.8 Ų50.867%0.67225%0.253SS*.Iπ-helixtrans-69-37.7-173.9-176.4175.8-179.9170-0.2113.5A138 Y139 R146A138-R142 WeakPolarHBondContact O-CB 3.28Å; A138-R142 PolarHBondContact O-N 3.48Å; Y139-R142 PolarHBondContact O-N 3.17Å; R142-R146 WeakPolarHBondContact O-CB 3.39Å
143H79.8Confident80.1Confident93 Ų9353.5 Ų53.543%0.43126%0.259SS..Iπ-helixtrans-108.7-40.3-167.7-68.6-76.4000114.1Y139 R147Y139-H143 AromaticContact CD2-CD2 3.45Å; Y139-H143 VanDerWaalsContact CD2-CD2 3.45Å; Y139-H143 WeakPolarHBondContact CD2-CD2 3.45Å; Y139-H143 AromaticContact CD2-NE2 3.83Å; Y139-H143 AromaticContact CE2-CD2 3.26Å; Y139-H143 WeakPolarHBondContact CE2-CD2 3.37Å; Y139-H143 AromaticContact CE2-NE2 3.45Å; Y139-H143 WeakPolarHBondContact CE2-NE2 3.37Å; Y139-H143 AromaticContact CG-CD2 4Å; Y139-H143 AromaticContact CZ-CD2 3.66Å; Y139-H143 PolarHBondContact O-CD2 3.43Å; Y139-H143 PolarHBondContact O-N 2.96Å; Y139-H143 VanDerWaalsContact O-N 3.1Å; H143-R147 WeakPolarHBondContact O-CB 3.38Å
144W82.9Confident79.1Confident19 Ų1963.4 Ų63.47%0.07230%0.302CS..Iπ-helixtrans-95.2-58-178.3-176.481.8000111Q82 G85 L86 Y89 L140 R146 R147 E148 I156Q82-W144 PolarHBondContact O-NE1 3.18Å; G85-W144 VanDerWaalsContact C-CE2 3.49Å; L86-W144 HydrophobicContact CB-CH2 4.44Å; L86-W144 HydrophobicContact CB-CZ2 3.7Å; L86-W144 HydrophobicContact CD1-CH2 3.97Å; L86-W144 HydrophobicContact CD1-CZ2 3.86Å; L86-W144 HydrophobicContact CG-CZ2 4.4Å; Y89-W144 HydrophobicContact CD1-CH2 4.19Å; Y89-W144 HydrophobicContact CD1-CZ3 4.18Å; Y89-W144 HydrophobicContact CD2-CE3 4.47Å; Y89-W144 HydrophobicContact CD2-CH2 4.45Å; Y89-W144 AromaticContact CD2-CZ3 3.65Å; Y89-W144 HydrophobicContact CD2-CZ3 3.65Å; Y89-W144 HydrophobicContact CE2-CZ3 4.37Å; Y89-W144 AromaticContact CG-CH2 3.91Å; Y89-W144 HydrophobicContact CG-CH2 3.91Å; Y89-W144 AromaticContact CG-CZ3 3.53Å; Y89-W144 HydrophobicContact CG-CZ3 3.53Å; L140-W144 HydrophobicContact CD1-CB 3.8Å; L140-W144 HydrophobicContact CD1-CD2 4.2Å; L140-W144 HydrophobicContact CD1-CE3 4.01Å; L140-W144 HydrophobicContact CD1-CG 4.13Å; L140-W144 HydrophobicContact CG-CE3 4.41Å; L140-W144 PolarHBondContact O-N 3.17Å; W144-R146 VanDerWaalsContact C-N 3.34Å; W144-R146 PolarHBondContact O-N 2.83Å; W144-R147 WeakPolarHBondContact O-CB 3.37Å; W144-R147 PolarHBondContact O-N 2.97Å; W144-R147 VanDerWaalsContact O-N 3.13Å; W144-E148 HydrophobicContact CD2-CG 3.89Å; W144-E148 HydrophobicContact CE3-CG 4.35Å; W144-E148 HydrophobicContact CG-CG 4.32Å; W144-E148 HydrophobicContact CH2-CG 4.18Å; W144-E148 HydrophobicContact CZ2-CG 3.7Å; W144-E148 WeakPolarHBondContact CZ2-OE2 3.44Å; W144-E148 HydrophobicContact CZ3-CG 4.48Å; W144-E148 WeakPolarHBondContact O-CG 3.27Å; W144-E148 PolarHBondContact O-N 3.35Å; W144-I156 HydrophobicContact CH2-CD1 3.99Å; W144-I156 HydrophobicContact CH2-CG1 4.49Å; W144-I156 HydrophobicContact CH2-CG2 4.23Å; W144-I156 HydrophobicContact CZ2-CD1 4.48Å; W144-I156 HydrophobicContact CZ3-CG2 3.94Å
145V78.9Confident78.2Confident6 Ų663.8 Ų63.84%0.03631%0.313CS..Iπ-helixtrans-56.2-48.9-177.71760000110.9Y89 L140 R147 E148 C149 I156 Y157Y89-V145 HydrophobicContact CD2-CG2 4.45Å; Y89-V145 HydrophobicContact CE2-CG2 4.47Å; L140-V145 HydrophobicContact CG-CG2 4.41Å; L140-V145 PolarHBondContact O-N 3.08Å; V145-R147 VanDerWaalsContact C-N 3.32Å; V145-R147 PolarHBondContact O-N 3.37Å; V145-E148 PolarHBondContact O-N 3.1Å; V145-C149 PolarHBondContact O-N 3.43Å; V145-C149 PolarHBondContact O-SG 3.15Å; V145-I156 HydrophobicContact CG1-CG2 4.13Å; V145-Y157 WeakPolarHBondContact CG1-O 3.11Å
146R77.8Confident77.9Confident142 Ų14263.7 Ų63.754%0.53631%0.308SS..Hα-helixtrans-56.5-44.8179-170.2172.9-174.2159.63.2112.8N141 R142 W144 E148 C149 D150 F219N141-R146 PolarHBondContact O-N 2.76Å; R142-R146 WeakPolarHBondContact O-CB 3.39Å; W144-R146 VanDerWaalsContact C-N 3.34Å; W144-R146 PolarHBondContact O-N 2.83Å; R146-E148 PolarHBondContact O-N 2.73Å; R146-C149 PolarHBondContact O-N 2.94Å; R146-D150 WeakPolarHBondContact O-CB 3.46Å; R146-D150 PolarHBondContact O-N 2.98Å; R146-F219 HydrophobicContact CG-CE1 4.24Å; R146-F219 HydrophobicContact CG-CZ 4.03Å
147R78Confident77.5Confident150 Ų15066 Ų6657%0.56632%0.317SS*.Hα-helixtrans-63.8-41.6178.8-174.6-174.2-166.815410.7111.9H143 W144 V145 D150 E151H143-R147 WeakPolarHBondContact O-CB 3.38Å; W144-R147 WeakPolarHBondContact O-CB 3.37Å; W144-R147 PolarHBondContact O-N 2.97Å; W144-R147 VanDerWaalsContact O-N 3.13Å; V145-R147 VanDerWaalsContact C-N 3.32Å; V145-R147 PolarHBondContact O-N 3.37Å; R147-D150 PolarHBondContact O-N 2.85Å; R147-E151 IonicContact NE-OE1 3.7Å; R147-E151 PolarHBondContact NE-OE1 3.1Å; R147-E151 WeakPolarHBondContact O-CB 3.38Å; R147-E151 VanDerWaalsContact O-CG 3.28Å; R147-E151 WeakPolarHBondContact O-CG 3.29Å; R147-E151 PolarHBondContact O-N 2.91Å
148E76.9Confident77.4Confident0 Ų070.2 Ų70.20%034%0.337CS..Hα-helixtrans-70.6-34.7-178.6-60.1-86.2124.800111.8Q82 W144 V145 R146 R153 I156Q82-E148 PolarHBondContact NE2-OE1 3.34Å; W144-E148 HydrophobicContact CD2-CG 3.89Å; W144-E148 HydrophobicContact CE3-CG 4.35Å; W144-E148 HydrophobicContact CG-CG 4.32Å; W144-E148 HydrophobicContact CH2-CG 4.18Å; W144-E148 HydrophobicContact CZ2-CG 3.7Å; W144-E148 WeakPolarHBondContact CZ2-OE2 3.44Å; W144-E148 HydrophobicContact CZ3-CG 4.48Å; W144-E148 WeakPolarHBondContact O-CG 3.27Å; W144-E148 PolarHBondContact O-N 3.35Å; V145-E148 PolarHBondContact O-N 3.1Å; R146-E148 PolarHBondContact O-N 2.73Å; E148-R153 PolarHBondContact O-N 2.85Å; E148-R153 IonicContact OE1-CZ 3.36Å; E148-R153 IonicContact OE1-NH1 2.77Å; E148-R153 IonicContact OE1-NH2 3.05Å; E148-R153 PolarHBondContact OE1-NH2 3.36Å; E148-R153 IonicContact OE2-CZ 2.86Å; E148-R153 IonicContact OE2-NE 2.56Å; E148-R153 IonicContact OE2-NH1 3.63Å; E148-R153 PolarHBondContact OE2-NH1 2.97Å; E148-R153 IonicContact OE2-NH2 3.1Å; E148-R153 PolarHBondContact OE2-NH2 3.14Å; E148-I156 HydrophobicContact CB-CD1 3.72Å; E148-I156 HydrophobicContact CB-CG2 4.29Å; E148-I156 HydrophobicContact CG-CD1 4.26Å
149C71.3Confident77.5Confident27 Ų2768.3 Ų68.318%0.18232%0.321CS..Hα-helixtrans-66.5-44.4170.2-64.80000111.6V145 R146 E151 G152 F219V145-C149 PolarHBondContact O-N 3.43Å; V145-C149 PolarHBondContact O-SG 3.15Å; R146-C149 PolarHBondContact O-N 2.94Å; C149-E151 VanDerWaalsContact C-N 3.25Å; C149-E151 PolarHBondContact O-N 2.87Å; C149-G152 PolarHBondContact O-N 3.43Å; C149-F219 HydrophobicContact CB-CE2 4.09Å; C149-F219 HydrophobicContact CB-CZ 4.15Å
150D71.8Confident77.7Confident111 Ų11167.9 Ų67.959%0.59432%0.319SS*.Hα-helixtrans-64.1-29.6177.3-67-19.3000112.3R146 R147 G152R146-D150 WeakPolarHBondContact O-CB 3.46Å; R146-D150 PolarHBondContact O-N 2.98Å; R147-D150 PolarHBondContact O-N 2.85Å; D150-G152 PolarHBondContact O-N 3.07Å
151E75.4Confident77.7Confident93 Ų9369.2 Ų69.244%0.43533%0.328SS..THydrogen-bonded Turntrans-782.9173.5-73.5174.4-170.700113.5Q82 R147 C149 R153Q82-E151 PolarHBondContact NE2-OE2 3.34Å; R147-E151 IonicContact NE-OE1 3.7Å; R147-E151 PolarHBondContact NE-OE1 3.1Å; R147-E151 WeakPolarHBondContact O-CB 3.38Å; R147-E151 VanDerWaalsContact O-CG 3.28Å; R147-E151 WeakPolarHBondContact O-CG 3.29Å; R147-E151 PolarHBondContact O-N 2.91Å; C149-E151 VanDerWaalsContact C-N 3.25Å; C149-E151 PolarHBondContact O-N 2.87Å; E151-R153 IonicContact OE2-CZ 2.69Å; E151-R153 IonicContact OE2-NH2 3.5Å; E151-R153 PolarHBondContact OE2-NH2 3.31Å
152G62.8Low77.8Confident59 Ų5968.6 Ų68.661%0.60833%0.325SS*.THydrogen-bonded Turntrans78.516.3172.700000115.3C149 D150 K154C149-G152 PolarHBondContact O-N 3.43Å; D150-G152 PolarHBondContact O-N 3.07Å; G152-K154 PolarHBondContact O-N 2.9Å
153R69.9Low78.1Confident92 Ų9260.1 Ų60.135%0.34729%0.293SS..  trans-78.7112.6178.1-87.9-175.2-93.9164.24.7111.8E148 E151 I156E148-R153 PolarHBondContact O-N 2.85Å; E148-R153 IonicContact OE1-CZ 3.36Å; E148-R153 IonicContact OE1-NH1 2.77Å; E148-R153 IonicContact OE1-NH2 3.05Å; E148-R153 PolarHBondContact OE1-NH2 3.36Å; E148-R153 IonicContact OE2-CZ 2.86Å; E148-R153 IonicContact OE2-NE 2.56Å; E148-R153 IonicContact OE2-NH1 3.63Å; E148-R153 PolarHBondContact OE2-NH1 2.97Å; E148-R153 IonicContact OE2-NH2 3.1Å; E148-R153 PolarHBondContact OE2-NH2 3.14Å; E151-R153 IonicContact OE2-CZ 2.69Å; E151-R153 IonicContact OE2-NH2 3.5Å; E151-R153 PolarHBondContact OE2-NH2 3.31Å; R153-I156 HydrophobicContact CB-CD1 4.2Å
154K66.1Low78.5Confident209 Ų20956.1 Ų56.191%0.90928%0.275SS*.THydrogen-bonded Turntrans-69.4140.9175.9-60.9-169.9177-168.70111.3G152G152-K154 PolarHBondContact O-N 2.9Å
155G68.4Low78.7Confident37 Ų3756.2 Ų56.238%0.38128%0.277SS..THydrogen-bonded Turntrans91.97.617500000116.1
156I80.1Confident79.1Confident19 Ų1956.3 Ų56.310%0.09728%0.278CS..  trans-105.2130.8168.5-62.6171.3000107.9Y89 W144 V145 E148 R153Y89-I156 HydrophobicContact CE2-CG2 4.42Å; W144-I156 HydrophobicContact CH2-CD1 3.99Å; W144-I156 HydrophobicContact CH2-CG1 4.49Å; W144-I156 HydrophobicContact CH2-CG2 4.23Å; W144-I156 HydrophobicContact CZ2-CD1 4.48Å; W144-I156 HydrophobicContact CZ3-CG2 3.94Å; V145-I156 HydrophobicContact CG1-CG2 4.13Å; E148-I156 HydrophobicContact CB-CD1 3.72Å; E148-I156 HydrophobicContact CB-CG2 4.29Å; E148-I156 HydrophobicContact CG-CD1 4.26Å; R153-I156 HydrophobicContact CB-CD1 4.2Å
157Y80.6Confident79.8Confident48 Ų4849.5 Ų49.519%0.18825%0.253CS..  trans-131.7159.7-174.8-57.8-78.7000109.6Y89 V145 V165Y89-Y157 VanDerWaalsContact CE2-O 3.29Å; Y89-Y157 WeakPolarHBondContact CE2-O 3.3Å; Y89-Y157 PolarHBondContact OH-N 3.34Å; Y89-Y157 PolarHBondContact OH-O 2.79Å; V145-Y157 WeakPolarHBondContact CG1-O 3.11Å; Y157-V165 HydrophobicContact CD2-CG2 4.24Å; Y157-V165 HydrophobicContact CE2-CG2 4.11Å
158E85.1Confident80.3Confident89 Ų8943.8 Ų43.842%0.41623%0.231SC..  trans-55.3147.4163.5-161.1-174.3169.100109.9N134 N141 Y160 S161 L162N134-E158 PolarHBondContact ND2-OE1 3.11Å; N134-E158 PolarHBondContact OD1-OE1 3.42Å; N141-E158 HydrophobicContact CB-CG 4.08Å; N141-E158 WeakPolarHBondContact ND2-CG 3.48Å; N141-E158 PolarHBondContact ND2-OE1 2.92Å; N141-E158 WeakPolarHBondContact OD1-CG 3.32Å; E158-Y160 PolarHBondContact O-N 2.84Å; E158-Y160 VanDerWaalsContact O-N 3.16Å; E158-S161 CarbonylContact O-C 3.53Å; E158-S161 WeakPolarHBondContact O-CA 3.41Å; E158-S161 WeakPolarHBondContact O-CB 3.41Å; E158-S161 PolarHBondContact O-N 2.99Å; E158-L162 PolarHBondContact O-N 3.21Å
159I87.1Confident80.8Confident0 Ų047.1 Ų47.10%025%0.247CC..Hα-helixtrans-56.3-36.2-174.7-66.2-61.4000113.1Y89 L92 L133 C137 L140 N141 L162 A163Y89-I159 HydrophobicContact CD2-CD1 3.74Å; Y89-I159 HydrophobicContact CE2-CD1 3.85Å; L92-I159 HydrophobicContact CD1-CD1 3.86Å; L133-I159 HydrophobicContact CD2-CG2 3.91Å; L133-I159 HydrophobicContact CG-CG2 3.79Å; C137-I159 HydrophobicContact CB-CB 4.32Å; C137-I159 HydrophobicContact CB-CG1 3.77Å; C137-I159 HydrophobicContact CB-CG2 4.4Å; L140-I159 HydrophobicContact CD2-CD1 4.17Å; L140-I159 HydrophobicContact CD2-CG1 4.44Å; N141-I159 WeakPolarHBondContact OD1-CG1 3.46Å; N141-I159 PolarHBondContact OD1-N 3.08Å; N141-I159 VanDerWaalsContact OD1-N 3.08Å; I159-L162 HydrophobicContact CD1-CD2 4.1Å; I159-L162 WeakPolarHBondContact O-CB 3.29Å; I159-L162 PolarHBondContact O-N 3.44Å; I159-A163 PolarHBondContact O-N 3.17Å
160Y87.1Confident81.6Confident38 Ų3846.7 Ų46.715%0.14924%0.244CC..Hα-helixtrans-63.9-48.3172.5-174.1-112.3000112.1K131 N134 E158 L162 A163 L164 E210K131-Y160 HydrophobicContact CD-CE2 4.39Å; K131-Y160 WeakPolarHBondContact CE-OH 3.45Å; K131-Y160 HydrophobicContact CG-CD2 3.87Å; K131-Y160 HydrophobicContact CG-CE2 3.47Å; K131-Y160 VanDerWaalsContact CG-CE2 3.47Å; N134-Y160 PolarHBondContact OD1-N 2.95Å; E158-Y160 PolarHBondContact O-N 2.84Å; E158-Y160 VanDerWaalsContact O-N 3.16Å; Y160-L162 VanDerWaalsContact C-N 3.3Å; Y160-L162 PolarHBondContact O-N 3.37Å; Y160-A163 WeakPolarHBondContact O-CB 3.48Å; Y160-A163 PolarHBondContact O-N 3.29Å; Y160-A163 VanDerWaalsContact O-N 3.1Å; Y160-L164 HydrophobicContact CD1-CD1 3.94Å; Y160-L164 HydrophobicContact CD1-CG 4.45Å; Y160-L164 HydrophobicContact CE1-CD1 3.61Å; Y160-L164 HydrophobicContact CE1-CG 4.19Å; Y160-L164 WeakPolarHBondContact O-CG 3.41Å; Y160-L164 PolarHBondContact O-N 3.44Å; Y160-E210 PolarHBondContact OH-OE2 2.94Å
161S84.8Confident82.5Confident28 Ų2841.4 Ų41.420%0.19622%0.215CC..Hα-helixtrans-62.7-35.9176-59.10000112.1E158 A163 L164 V165E158-S161 CarbonylContact O-C 3.53Å; E158-S161 WeakPolarHBondContact O-CA 3.41Å; E158-S161 WeakPolarHBondContact O-CB 3.41Å; E158-S161 PolarHBondContact O-N 2.99Å; S161-A163 VanDerWaalsContact C-N 3.35Å; S161-L164 PolarHBondContact O-N 2.9Å; S161-V165 WeakPolarHBondContact O-CG2 3.5Å; S161-V165 PolarHBondContact O-N 3.23Å
162L86.4Confident83.2Confident2 Ų237.1 Ų37.11%0.0120%0.195CC..Hα-helixtrans-61-43.1171.7174.465.4000111.3Y89 K93 L96 E158 I159 Y160 V165 T166Y89-L162 HydrophobicContact CD2-CD2 4.38Å; Y89-L162 HydrophobicContact CE1-CD2 4.34Å; Y89-L162 HydrophobicContact CE2-CD2 3.78Å; K93-L162 HydrophobicContact CB-CD1 4.33Å; K93-L162 HydrophobicContact CB-CD2 4.08Å; K93-L162 HydrophobicContact CD-CD1 4.01Å; K93-L162 HydrophobicContact CG-CD1 4Å; L96-L162 HydrophobicContact CD1-CD2 4.25Å; L96-L162 HydrophobicContact CD1-CG 4.26Å; E158-L162 PolarHBondContact O-N 3.21Å; I159-L162 HydrophobicContact CD1-CD2 4.1Å; I159-L162 WeakPolarHBondContact O-CB 3.29Å; I159-L162 PolarHBondContact O-N 3.44Å; Y160-L162 VanDerWaalsContact C-N 3.3Å; Y160-L162 PolarHBondContact O-N 3.37Å; L162-V165 PolarHBondContact O-N 2.97Å; L162-T166 WeakPolarHBondContact O-CB 3.47Å; L162-T166 PolarHBondContact O-N 2.7Å; L162-T166 PolarHBondContact O-OG1 3.4Å
163A88.3Confident84.4Confident0 Ų040.1 Ų40.10%019%0.188CC..Hα-helixtrans-62.6-42.8175.700000111.4L96 Y126 S130 I159 Y160 S161 T166 W167L96-A163 HydrophobicContact CD1-CB 4.24Å; Y126-A163 HydrophobicContact CE1-CB 3.95Å; Y126-A163 WeakPolarHBondContact CE1-O 3.42Å; Y126-A163 WeakPolarHBondContact OH-CA 3.3Å; Y126-A163 PolarHBondContact OH-O 2.67Å; S130-A163 VanDerWaalsContact OG-CB 3.31Å; S130-A163 WeakPolarHBondContact OG-CB 3.4Å; I159-A163 PolarHBondContact O-N 3.17Å; Y160-A163 WeakPolarHBondContact O-CB 3.48Å; Y160-A163 PolarHBondContact O-N 3.29Å; Y160-A163 VanDerWaalsContact O-N 3.1Å; S161-A163 VanDerWaalsContact C-N 3.35Å; A163-T166 PolarHBondContact O-N 3.01Å; A163-W167 WeakPolarHBondContact O-CB 3.42Å; A163-W167 PolarHBondContact O-N 3.1Å
164L88.1Confident85.4Confident9 Ų938.9 Ų38.95%0.04719%0.192CC..Hα-helixtrans-61.7-45.6174.6-65.2177.4000112.6W123 Y160 S161 T166 W167 R168 L211 L213W123-L164 HydrophobicContact CH2-CD2 3.46Å; W123-L164 VanDerWaalsContact CH2-CD2 3.46Å; W123-L164 HydrophobicContact CZ2-CD2 4.37Å; W123-L164 HydrophobicContact CZ3-CD2 4.1Å; Y160-L164 HydrophobicContact CD1-CD1 3.94Å; Y160-L164 HydrophobicContact CD1-CG 4.45Å; Y160-L164 HydrophobicContact CE1-CD1 3.61Å; Y160-L164 HydrophobicContact CE1-CG 4.19Å; Y160-L164 WeakPolarHBondContact O-CG 3.41Å; Y160-L164 PolarHBondContact O-N 3.44Å; S161-L164 PolarHBondContact O-N 2.9Å; L164-T166 VanDerWaalsContact C-N 3.3Å; L164-T166 PolarHBondContact O-N 2.75Å; L164-W167 PolarHBondContact O-N 2.99Å; L164-R168 WeakPolarHBondContact O-CB 3.44Å; L164-R168 PolarHBondContact O-N 3.22Å; L164-L211 HydrophobicContact CB-CD2 4.46Å; L164-L211 HydrophobicContact CD2-CD2 4.42Å; L164-L211 WeakPolarHBondContact O-CD2 3.38Å; L164-L213 HydrophobicContact CB-CD1 4.05Å; L164-L213 HydrophobicContact CD1-CD2 3.9Å
165V87.2Confident86.5Confident21 Ų2129 Ų2913%0.12715%0.149CC..Hα-helixtrans-60.1-42.4173.6173.10000110.6Y157 S161 L162 R168 E169 L213Y157-V165 HydrophobicContact CD2-CG2 4.24Å; Y157-V165 HydrophobicContact CE2-CG2 4.11Å; S161-V165 WeakPolarHBondContact O-CG2 3.5Å; S161-V165 PolarHBondContact O-N 3.23Å; L162-V165 PolarHBondContact O-N 2.97Å; V165-R168 WeakPolarHBondContact O-CB 3.37Å; V165-R168 PolarHBondContact O-N 3.45Å; V165-E169 HydrophobicContact CG1-CG 4.44Å; V165-E169 WeakPolarHBondContact O-CG 3.5Å; V165-E169 PolarHBondContact O-N 2.94Å; V165-L213 HydrophobicContact CG2-CD1 3.41Å; V165-L213 VanDerWaalsContact CG2-CD1 3.41Å
166T88.1Confident87.5Confident8 Ų827.9 Ų27.95%0.04913%0.134CC..Hα-helixtrans-68.6-39.3-178.4-47.20000111.2L96 K97 L100 L162 A163 L164 E169 C170L96-T166 HydrophobicContact CB-CG2 4.05Å; K97-T166 HydrophobicContact CB-CG2 4.19Å; L100-T166 VanDerWaalsContact CD1-C 3.49Å; L100-T166 HydrophobicContact CD1-CG2 3.76Å; L162-T166 WeakPolarHBondContact O-CB 3.47Å; L162-T166 PolarHBondContact O-N 2.7Å; L162-T166 PolarHBondContact O-OG1 3.4Å; A163-T166 PolarHBondContact O-N 3.01Å; L164-T166 VanDerWaalsContact C-N 3.3Å; L164-T166 PolarHBondContact O-N 2.75Å; T166-E169 PolarHBondContact O-N 3.05Å; T166-C170 VanDerWaalsContact O-CB 3.29Å; T166-C170 WeakPolarHBondContact O-CB 3.43Å; T166-C170 PolarHBondContact O-N 3.44Å; T166-C170 PolarHBondContact O-SG 2.98Å
167W91.8Very high87.9Confident0 Ų034.5 Ų34.50%016%0.163CC..Hα-helixtrans-59.8-46.5170.2-178.8-81.3000111.6L100 Y119 Q122 W123 Y126 A163 L164 E169 L171 F172 L211L100-W167 HydrophobicContact CD1-CB 4.38Å; L100-W167 HydrophobicContact CD2-CE3 3.58Å; L100-W167 HydrophobicContact CD2-CZ3 3.94Å; Y119-W167 HydrophobicContact CD2-CZ2 4.18Å; Y119-W167 HydrophobicContact CE1-CZ2 4.46Å; Y119-W167 AromaticContact CE2-CZ2 3.72Å; Y119-W167 HydrophobicContact CE2-CZ2 3.72Å; Y119-W167 AromaticContact CE2-NE1 3.83Å; Y119-W167 AromaticContact CZ-CZ2 3.87Å; Y119-W167 AromaticContact CZ-NE1 3.62Å; Y119-W167 PolarHBondContact OH-NE1 2.95Å; Q122-W167 HydrophobicContact CB-CH2 3.92Å; W123-W167 VanDerWaalsContact CA-CH2 3.46Å; W123-W167 HydrophobicContact CB-CH2 3.99Å; W123-W167 HydrophobicContact CB-CZ2 3.78Å; W123-W167 HydrophobicContact CD2-CZ2 4.36Å; W123-W167 AromaticContact CE3-CD1 3.97Å; W123-W167 AromaticContact CE3-CD2 3.64Å; W123-W167 HydrophobicContact CE3-CD2 3.64Å; W123-W167 AromaticContact CE3-CE2 3.36Å; W123-W167 HydrophobicContact CE3-CE3 4.19Å; W123-W167 HydrophobicContact CE3-CG 4.01Å; W123-W167 HydrophobicContact CE3-CH2 4.22Å; W123-W167 AromaticContact CE3-CZ2 3.66Å; W123-W167 HydrophobicContact CE3-CZ2 3.66Å; W123-W167 HydrophobicContact CE3-CZ3 4.47Å; W123-W167 AromaticContact CE3-NE1 3.57Å; W123-W167 HydrophobicContact CG-CZ2 4.46Å; W123-W167 HydrophobicContact CZ3-CB 4.35Å; W123-W167 AromaticContact CZ3-CD1 3.63Å; W123-W167 AromaticContact CZ3-CD2 3.82Å; W123-W167 HydrophobicContact CZ3-CD2 3.82Å; W123-W167 AromaticContact CZ3-CE2 3.85Å; W123-W167 AromaticContact CZ3-CG 3.68Å; W123-W167 HydrophobicContact CZ3-CG 3.68Å; W123-W167 AromaticContact CZ3-NE1 3.72Å; Y126-W167 VanDerWaalsContact CB-CZ3 3.48Å; Y126-W167 HydrophobicContact CD1-CB 4.39Å; Y126-W167 HydrophobicContact CD1-CD2 4.16Å; Y126-W167 AromaticContact CD1-CE3 3.38Å; Y126-W167 HydrophobicContact CD1-CE3 3.38Å; Y126-W167 HydrophobicContact CD1-CZ3 4Å; Y126-W167 HydrophobicContact CD2-CE3 4.03Å; Y126-W167 HydrophobicContact CD2-CZ3 4.2Å; Y126-W167 HydrophobicContact CE1-CB 3.92Å; Y126-W167 AromaticContact CE1-CE3 3.9Å; Y126-W167 HydrophobicContact CE1-CE3 3.9Å; Y126-W167 HydrophobicContact CE2-CE3 4.48Å; Y126-W167 AromaticContact CG-CE3 3.47Å; Y126-W167 HydrophobicContact CG-CE3 3.47Å; Y126-W167 VanDerWaalsContact CG-CE3 3.47Å; Y126-W167 AromaticContact CG-CZ3 3.64Å; Y126-W167 HydrophobicContact CG-CZ3 3.64Å; A163-W167 WeakPolarHBondContact O-CB 3.42Å; A163-W167 PolarHBondContact O-N 3.1Å; L164-W167 PolarHBondContact O-N 2.99Å; W167-E169 VanDerWaalsContact C-N 3.3Å; W167-E169 PolarHBondContact O-N 3.45Å; W167-L171 HydrophobicContact CD2-CB 4.27Å; W167-L171 HydrophobicContact CD2-CD2 4.16Å; W167-L171 HydrophobicContact CE3-CD2 4.02Å; W167-L171 HydrophobicContact CH2-CD2 3.15Å; W167-L171 HydrophobicContact CZ2-CD2 3.31Å; W167-L171 HydrophobicContact CZ3-CD2 3.53Å; W167-L171 PolarHBondContact O-N 3.32Å; W167-F172 PolarHBondContact O-N 3.3Å; W167-L211 HydrophobicContact CB-CD2 4.28Å; W167-L211 HydrophobicContact CG-CD2 4.23Å
168R88.8Confident88.4Confident29 Ų2935 Ų3511%0.10917%0.166CC..Iπ-helixtrans-53.9-48.1177.9-166.3177.970.7-178.53.1111.4L164 V165 F172 R173 L211 E215L164-R168 WeakPolarHBondContact O-CB 3.44Å; L164-R168 PolarHBondContact O-N 3.22Å; V165-R168 WeakPolarHBondContact O-CB 3.37Å; V165-R168 PolarHBondContact O-N 3.45Å; R168-F172 HydrophobicContact CG-CD1 4.08Å; R168-R173 WeakPolarHBondContact O-CB 3.48Å; R168-R173 WeakPolarHBondContact O-CG 3.38Å; R168-R173 PolarHBondContact O-N 2.96Å; R168-L211 HydrophobicContact CB-CD2 4.19Å; R168-E215 IonicContact CZ-OE1 3.81Å; R168-E215 IonicContact NH1-OE1 2.63Å; R168-E215 PolarHBondContact NH1-OE1 3.43Å; R168-E215 IonicContact NH2-OE1 3.41Å; R168-E215 PolarHBondContact NH2-OE1 2.88Å
169E87.8Confident88.7Confident71 Ų7130.7 Ų30.733%0.33215%0.146SC..Iπ-helixtrans-77.1-42-176.4-65.8-58.3141.900113.7V165 T166 W167 R173V165-E169 HydrophobicContact CG1-CG 4.44Å; V165-E169 WeakPolarHBondContact O-CG 3.5Å; V165-E169 PolarHBondContact O-N 2.94Å; T166-E169 PolarHBondContact O-N 3.05Å; W167-E169 VanDerWaalsContact C-N 3.3Å; W167-E169 PolarHBondContact O-N 3.45Å; E169-R173 VanDerWaalsContact CD-NH1 3.27Å; E169-R173 IonicContact OE1-CZ 2.7Å; E169-R173 IonicContact OE1-NE 3.85Å; E169-R173 IonicContact OE1-NH1 2.79Å; E169-R173 PolarHBondContact OE1-NH1 3.48Å; E169-R173 VanDerWaalsContact OE1-NH1 3.12Å; E169-R173 IonicContact OE1-NH2 3.56Å; E169-R173 IonicContact OE2-CZ 3.05Å; E169-R173 IonicContact OE2-NE 2.72Å; E169-R173 IonicContact OE2-NH1 3.74Å; E169-R173 PolarHBondContact OE2-NH1 3.43Å
170C88.9Confident89Confident18 Ų1831.1 Ų31.112%0.12215%0.149CC..Iπ-helixtrans-96.9-24.5-167.5-55.10000114.2L100 T166L100-C170 HydrophobicContact CB-CB 3.75Å; L100-C170 HydrophobicContact CD1-CB 4.28Å; T166-C170 VanDerWaalsContact O-CB 3.29Å; T166-C170 WeakPolarHBondContact O-CB 3.43Å; T166-C170 PolarHBondContact O-N 3.44Å; T166-C170 PolarHBondContact O-SG 2.98Å
171L89.4Confident89.2Confident0 Ų033.5 Ų33.50%016%0.164CC..Iπ-helixtrans-123.1-48.4-176.8-153.885000112.6L103 L104 Y119 W167 P174 L175L103-L171 HydrophobicContact CD2-CD2 4.47Å; L103-L171 HydrophobicContact CG-CD1 4.43Å; L104-L171 HydrophobicContact CB-CD1 3.89Å; L104-L171 HydrophobicContact CD1-CD1 4.01Å; Y119-L171 HydrophobicContact CD2-CD2 4.46Å; Y119-L171 HydrophobicContact CE2-CD2 4.49Å; W167-L171 HydrophobicContact CD2-CB 4.27Å; W167-L171 HydrophobicContact CD2-CD2 4.16Å; W167-L171 HydrophobicContact CE3-CD2 4.02Å; W167-L171 HydrophobicContact CH2-CD2 3.15Å; W167-L171 HydrophobicContact CZ2-CD2 3.31Å; W167-L171 HydrophobicContact CZ3-CD2 3.53Å; W167-L171 PolarHBondContact O-N 3.32Å; L171-P174 WeakPolarHBondContact O-CD 3.36Å; L171-L175 HydrophobicContact CD1-CD1 4.39Å; L171-L175 HydrophobicContact CG-CD1 4.1Å; L171-L175 WeakPolarHBondContact O-CB 3.44Å; L171-L175 PolarHBondContact O-N 2.92Å
172F90.3Very high89.6Confident2 Ų232.3 Ų32.31%0.00916%0.156CC..Iπ-helixtrans-65.3-54.5179.6169.1-92.8000111.9W167 R168 L175 N176 Y208 L211 V227 Y231W167-F172 PolarHBondContact O-N 3.3Å; R168-F172 HydrophobicContact CG-CD1 4.08Å; F172-L175 PolarHBondContact O-N 3.16Å; F172-N176 HydrophobicContact CD1-CB 4.46Å; F172-N176 HydrophobicContact CD2-CB 4.24Å; F172-N176 HydrophobicContact CE1-CB 4.21Å; F172-N176 HydrophobicContact CE2-CB 4Å; F172-N176 HydrophobicContact CG-CB 4.47Å; F172-N176 HydrophobicContact CZ-CB 3.96Å; F172-N176 WeakPolarHBondContact O-CA 3.48Å; F172-N176 WeakPolarHBondContact O-CB 3.14Å; F172-N176 PolarHBondContact O-N 2.77Å; F172-Y208 HydrophobicContact CD2-CD1 4.14Å; F172-Y208 AromaticContact CD2-CE1 3.78Å; F172-Y208 HydrophobicContact CD2-CE1 3.78Å; F172-Y208 AromaticContact CE2-CD1 3.65Å; F172-Y208 HydrophobicContact CE2-CD1 3.65Å; F172-Y208 HydrophobicContact CE2-CD2 4.06Å; F172-Y208 AromaticContact CE2-CE1 3.4Å; F172-Y208 HydrophobicContact CE2-CE1 3.4Å; F172-Y208 VanDerWaalsContact CE2-CE1 3.4Å; F172-Y208 AromaticContact CE2-CE2 3.83Å; F172-Y208 HydrophobicContact CE2-CE2 3.83Å; F172-Y208 AromaticContact CE2-CG 3.99Å; F172-Y208 HydrophobicContact CE2-CG 3.99Å; F172-Y208 AromaticContact CE2-CZ 3.5Å; F172-Y208 VanDerWaalsContact CE2-CZ 3.5Å; F172-Y208 HydrophobicContact CZ-CE2 4.41Å; F172-L211 HydrophobicContact CB-CD1 4.01Å; F172-L211 HydrophobicContact CD2-CD1 3.68Å; F172-L211 HydrophobicContact CE2-CD1 4.3Å; F172-L211 HydrophobicContact CG-CD1 3.85Å; F172-V227 HydrophobicContact CE1-CG1 3.84Å; F172-V227 HydrophobicContact CE2-CG1 3.98Å; F172-V227 HydrophobicContact CZ-CG1 3.39Å; F172-Y231 HydrophobicContact CE1-CD1 4.39Å; F172-Y231 HydrophobicContact CE1-CD2 4.11Å; F172-Y231 HydrophobicContact CE1-CE2 4.32Å; F172-Y231 HydrophobicContact CE1-CG 4.16Å; F172-Y231 HydrophobicContact CZ-CD1 4.26Å; F172-Y231 AromaticContact CZ-CD2 3.89Å; F172-Y231 HydrophobicContact CZ-CD2 3.89Å; F172-Y231 AromaticContact CZ-CG 3.74Å; F172-Y231 HydrophobicContact CZ-CG 3.74Å
173R88.8Confident89.9Confident123 Ų12332.2 Ų32.246%0.46416%0.156SC..Hα-helixtrans-56.1-41-177.9-88-177.9176.9-176.9-3.8114.1R168 E169 N176R168-R173 WeakPolarHBondContact O-CB 3.48Å; R168-R173 WeakPolarHBondContact O-CG 3.38Å; R168-R173 PolarHBondContact O-N 2.96Å; E169-R173 VanDerWaalsContact CD-NH1 3.27Å; E169-R173 IonicContact OE1-CZ 2.7Å; E169-R173 IonicContact OE1-NE 3.85Å; E169-R173 IonicContact OE1-NH1 2.79Å; E169-R173 PolarHBondContact OE1-NH1 3.48Å; E169-R173 VanDerWaalsContact OE1-NH1 3.12Å; E169-R173 IonicContact OE1-NH2 3.56Å; E169-R173 IonicContact OE2-CZ 3.05Å; E169-R173 IonicContact OE2-NE 2.72Å; E169-R173 IonicContact OE2-NH1 3.74Å; E169-R173 PolarHBondContact OE2-NH1 3.43Å; R173-N176 PolarHBondContact O-OD1 3.43Å; R173-N176 VanDerWaalsContact O-OD1 3.08Å
174P90.1Very high90.1Very high65 Ų6532.9 Ų32.942%0.42216%0.159SC..Hα-helixtrans-68.5-41.9174.3-25.736.5000114.2L104 L171L104-P174 HydrophobicContact CD1-CB 3.84Å; L104-P174 HydrophobicContact CD1-CG 4.31Å; L104-P174 HydrophobicContact CD2-CB 4.06Å; L104-P174 HydrophobicContact CD2-CG 3.97Å; L171-P174 WeakPolarHBondContact O-CD 3.36Å
175L89.6Confident90.3Very high2 Ų237 Ų371%0.0118%0.177CC..Hα-helixtrans-95.3-11.8-171.9-62.2179.8000114.5L104 F118 L171 F172 K177 Q178 V179L104-L175 HydrophobicContact CD1-CD1 3.98Å; L104-L175 HydrophobicContact CD1-CD2 3.99Å; L104-L175 HydrophobicContact CD1-CG 3.72Å; F118-L175 HydrophobicContact CE1-CD1 4.4Å; L171-L175 HydrophobicContact CD1-CD1 4.39Å; L171-L175 HydrophobicContact CG-CD1 4.1Å; L171-L175 WeakPolarHBondContact O-CB 3.44Å; L171-L175 PolarHBondContact O-N 2.92Å; F172-L175 PolarHBondContact O-N 3.16Å; L175-K177 VanDerWaalsContact C-N 3.31Å; L175-K177 PolarHBondContact O-N 3.35Å; L175-Q178 PolarHBondContact O-N 3.02Å; L175-Q178 VanDerWaalsContact O-N 3.08Å; L175-V179 HydrophobicContact CB-CG2 4.1Å; L175-V179 WeakPolarHBondContact O-CG2 3.36Å; L175-V179 PolarHBondContact O-N 3.47Å
176N88.9Confident90.6Very high14 Ų1436.5 Ų36.58%0.07517%0.173CC..Hα-helixtrans-54-43.1-170.362-6.5000112.9F172 R173 Q178 V179 T180 Y208 Y231F172-N176 HydrophobicContact CD1-CB 4.46Å; F172-N176 HydrophobicContact CD2-CB 4.24Å; F172-N176 HydrophobicContact CE1-CB 4.21Å; F172-N176 HydrophobicContact CE2-CB 4Å; F172-N176 HydrophobicContact CG-CB 4.47Å; F172-N176 HydrophobicContact CZ-CB 3.96Å; F172-N176 WeakPolarHBondContact O-CA 3.48Å; F172-N176 WeakPolarHBondContact O-CB 3.14Å; F172-N176 PolarHBondContact O-N 2.77Å; R173-N176 PolarHBondContact O-OD1 3.43Å; R173-N176 VanDerWaalsContact O-OD1 3.08Å; N176-Q178 PolarHBondContact O-N 3.12Å; N176-V179 PolarHBondContact O-N 3.48Å; N176-T180 VanDerWaalsContact O-CB 3.24Å; N176-T180 WeakPolarHBondContact O-CB 3.45Å; N176-T180 PolarHBondContact O-N 3.39Å; N176-T180 PolarHBondContact O-OG1 2.82Å; N176-Y208 PolarHBondContact O-OH 3.08Å; N176-Y231 WeakPolarHBondContact ND2-CD1 3.36Å; N176-Y231 WeakPolarHBondContact ND2-CE1 3.26Å
177K89.9Confident90.9Very high158 Ų15836.1 Ų36.169%0.68717%0.171SC*.Hα-helixtrans-62.6-45.8180-69.6-177.5-179.2179.80111.6L175 N181L175-K177 VanDerWaalsContact C-N 3.31Å; L175-K177 PolarHBondContact O-N 3.35Å; K177-N181 VanDerWaalsContact O-CB 3.22Å; K177-N181 WeakPolarHBondContact O-CB 3.11Å; K177-N181 PolarHBondContact O-N 3.09Å; K177-N181 PolarHBondContact O-ND2 2.97Å
178Q90.6Very high90.9Very high57 Ų5740.1 Ų40.127%0.26619%0.189SC..Hα-helixtrans-67.1-43.7179.5-63.2173.8-12.600110.8E108 M111 L175 N176 A182E108-Q178 PolarHBondContact O-NE2 3.36Å; M111-Q178 HydrophobicContact SD-CB 4.43Å; M111-Q178 HydrophobicContact SD-CG 4.09Å; L175-Q178 PolarHBondContact O-N 3.02Å; L175-Q178 VanDerWaalsContact O-N 3.08Å; N176-Q178 PolarHBondContact O-N 3.12Å; Q178-A182 WeakPolarHBondContact O-CB 3.48Å; Q178-A182 PolarHBondContact O-N 3.28Å
179V91.5Very high91.1Very high0 Ų043.5 Ų43.50%020%0.202CC..Hα-helixtrans-64.6-51.8178.5172.40000111.2V115 L116 Y119 L175 N176 N181 A182 V183 V204 Y208V115-V179 HydrophobicContact CG2-CG2 3.97Å; L116-V179 HydrophobicContact CD2-CG1 3.98Å; Y119-V179 HydrophobicContact CD1-CG1 4.29Å; Y119-V179 HydrophobicContact CD2-CG2 3.99Å; Y119-V179 HydrophobicContact CG-CG1 4.38Å; Y119-V179 HydrophobicContact CG-CG2 4.04Å; L175-V179 HydrophobicContact CB-CG2 4.1Å; L175-V179 WeakPolarHBondContact O-CG2 3.36Å; L175-V179 PolarHBondContact O-N 3.47Å; N176-V179 PolarHBondContact O-N 3.48Å; V179-N181 PolarHBondContact O-N 3.14Å; V179-A182 PolarHBondContact O-N 3.42Å; V179-V183 WeakPolarHBondContact O-CG2 3.45Å; V179-V183 PolarHBondContact O-N 2.87Å; V179-V204 HydrophobicContact CG1-CB 4.49Å; V179-V204 HydrophobicContact CG1-CG1 3.62Å; V179-V204 HydrophobicContact CG1-CG2 3.92Å; V179-Y208 HydrophobicContact CG1-CE1 4.35Å; V179-Y208 WeakPolarHBondContact CG1-OH 3.45Å
180T92.8Very high91.3Very high8 Ų842.2 Ų42.25%0.04920%0.196CC..Hα-helixtrans-57-48.4176.5-650000110.5N176 A182 V183 L184 Y208 Y231 F232N176-T180 VanDerWaalsContact O-CB 3.24Å; N176-T180 WeakPolarHBondContact O-CB 3.45Å; N176-T180 PolarHBondContact O-N 3.39Å; N176-T180 PolarHBondContact O-OG1 2.82Å; T180-A182 VanDerWaalsContact C-N 3.31Å; T180-A182 PolarHBondContact O-N 2.97Å; T180-V183 PolarHBondContact O-N 3.43Å; T180-V183 VanDerWaalsContact O-N 3.16Å; T180-L184 HydrophobicContact CG2-CD1 3.74Å; T180-L184 HydrophobicContact CG2-CG 4.21Å; T180-L184 VanDerWaalsContact O-CG 3.28Å; T180-L184 WeakPolarHBondContact O-CG 3.2Å; T180-L184 PolarHBondContact O-N 3.1Å; T180-Y208 PolarHBondContact OG1-OH 2.93Å; T180-Y208 VanDerWaalsContact OG1-OH 3.12Å; T180-Y231 WeakPolarHBondContact CG2-O 3.38Å; T180-Y231 PolarHBondContact OG1-O 3.49Å; T180-Y231 VanDerWaalsContact OG1-O 3.09Å; T180-F232 HydrophobicContact CG2-CD2 4.39Å
181N91.9Very high91.5Very high89 Ų8941.9 Ų41.948%0.47619%0.192SC..Hα-helixtrans-61.2-38.7179-72.5-15.3000112.5K177 V179 L184 K185K177-N181 VanDerWaalsContact O-CB 3.22Å; K177-N181 WeakPolarHBondContact O-CB 3.11Å; K177-N181 PolarHBondContact O-N 3.09Å; K177-N181 PolarHBondContact O-ND2 2.97Å; V179-N181 PolarHBondContact O-N 3.14Å; N181-L184 PolarHBondContact O-N 2.94Å; N181-K185 WeakPolarHBondContact O-CB 3.34Å; N181-K185 WeakPolarHBondContact O-CG 3.4Å; N181-K185 PolarHBondContact O-N 2.95Å
182A92.2Very high91.7Very high3 Ų346.6 Ų46.63%0.02522%0.218CC..Hα-helixtrans-66.4-4017600000112.1D112 V115 L116 Q178 V179 T180 L186D112-A182 WeakPolarHBondContact O-CB 3.29Å; V115-A182 HydrophobicContact CG1-CB 3.97Å; L116-A182 HydrophobicContact CD1-CB 3.89Å; L116-A182 HydrophobicContact CD2-CB 3.86Å; L116-A182 HydrophobicContact CG-CB 3.71Å; Q178-A182 WeakPolarHBondContact O-CB 3.48Å; Q178-A182 PolarHBondContact O-N 3.28Å; V179-A182 PolarHBondContact O-N 3.42Å; T180-A182 VanDerWaalsContact C-N 3.31Å; T180-A182 PolarHBondContact O-N 2.97Å; A182-L186 PolarHBondContact O-N 3.32Å
183V93.3Very high91.6Very high0 Ų049.6 Ų49.60%025%0.249CC..Hα-helixtrans-62-48.3173.5174.30000110.7L116 V179 T180 K185 L186 I187 I201 V204 F232L116-V183 HydrophobicContact CD1-CG2 4.39Å; L116-V183 HydrophobicContact CD2-CG2 3.57Å; V179-V183 WeakPolarHBondContact O-CG2 3.45Å; V179-V183 PolarHBondContact O-N 2.87Å; T180-V183 PolarHBondContact O-N 3.43Å; T180-V183 VanDerWaalsContact O-N 3.16Å; V183-K185 VanDerWaalsContact C-N 3.34Å; V183-K185 PolarHBondContact O-N 2.88Å; V183-L186 WeakPolarHBondContact O-CB 3.36Å; V183-L186 PolarHBondContact O-N 3.26Å; V183-L186 VanDerWaalsContact O-N 3.11Å; V183-I187 HydrophobicContact CG1-CD1 3.91Å; V183-I187 HydrophobicContact CG1-CG1 4.43Å; V183-I187 WeakPolarHBondContact O-CG1 3.49Å; V183-I187 PolarHBondContact O-N 2.72Å; V183-I201 HydrophobicContact CG1-CB 4.45Å; V183-I201 HydrophobicContact CG1-CG1 4.19Å; V183-I201 HydrophobicContact CG1-CG2 3.78Å; V183-V204 HydrophobicContact CG2-CB 4.07Å; V183-V204 HydrophobicContact CG2-CG1 3.95Å; V183-V204 HydrophobicContact CG2-CG2 4.1Å; V183-F232 HydrophobicContact CB-CE2 4.38Å; V183-F232 HydrophobicContact CG1-CD2 4.46Å; V183-F232 HydrophobicContact CG1-CE2 3.6Å; V183-F232 HydrophobicContact CG1-CZ 4.31Å
184L93.4Very high91.8Very high13 Ų1347.8 Ų47.87%0.06825%0.246CC..Hα-helixtrans-61.7-41.3-178.8-65.9172.3000111.9T180 N181 L186 I187 E188 F232 Q235 F236 D239T180-L184 HydrophobicContact CG2-CD1 3.74Å; T180-L184 HydrophobicContact CG2-CG 4.21Å; T180-L184 VanDerWaalsContact O-CG 3.28Å; T180-L184 WeakPolarHBondContact O-CG 3.2Å; T180-L184 PolarHBondContact O-N 3.1Å; N181-L184 PolarHBondContact O-N 2.94Å; L184-L186 PolarHBondContact O-N 3.06Å; L184-I187 PolarHBondContact O-N 3.45Å; L184-E188 PolarHBondContact O-N 3.3Å; L184-F232 HydrophobicContact CD2-CE2 4.16Å; L184-Q235 HydrophobicContact CD1-CB 4.21Å; L184-Q235 HydrophobicContact CD1-CG 3.5Å; L184-F236 HydrophobicContact CD2-CB 3.81Å; L184-F236 HydrophobicContact CD2-CD2 3.96Å; L184-F236 HydrophobicContact CD2-CG 4.4Å; L184-D239 WeakPolarHBondContact CD1-OD2 3.39Å
185K92.1Very high91.7Very high97 Ų9751.5 Ų51.542%0.42227%0.268SS..Hα-helixtrans-61.3-40.3172.4-78.9173.8168.6179.20113D112 N181 V183 E188 R189D112-K185 WeakPolarHBondContact OD1-CD 3.49Å; D112-K185 IonicContact OD1-NZ 2.62Å; D112-K185 PolarHBondContact OD1-NZ 2.88Å; N181-K185 WeakPolarHBondContact O-CB 3.34Å; N181-K185 WeakPolarHBondContact O-CG 3.4Å; N181-K185 PolarHBondContact O-N 2.95Å; V183-K185 VanDerWaalsContact C-N 3.34Å; V183-K185 PolarHBondContact O-N 2.88Å; K185-E188 PolarHBondContact O-N 3.34Å; K185-R189 VanDerWaalsContact O-CG 3.3Å; K185-R189 WeakPolarHBondContact O-CG 3.48Å; K185-R189 PolarHBondContact O-N 3.05Å
186L92.3Very high91.8Very high9 Ų952.8 Ų52.85%0.04727%0.274CS..Hα-helixtrans-64-42.6175-78.7-175.7000111.3L116 A182 V183 L184 E188 R189 E190 I196 I201L116-L186 HydrophobicContact CD1-CD1 3.32Å; L116-L186 HydrophobicContact CD1-CG 4.09Å; A182-L186 PolarHBondContact O-N 3.32Å; V183-L186 WeakPolarHBondContact O-CB 3.36Å; V183-L186 PolarHBondContact O-N 3.26Å; V183-L186 VanDerWaalsContact O-N 3.11Å; L184-L186 PolarHBondContact O-N 3.06Å; L186-E188 VanDerWaalsContact C-N 3.32Å; L186-E188 PolarHBondContact O-N 3.02Å; L186-R189 PolarHBondContact O-N 3.5Å; L186-E190 PolarHBondContact O-N 2.9Å; L186-I196 HydrophobicContact CD2-CG2 4.24Å; L186-I201 HydrophobicContact CB-CD1 4.28Å
187I93.8Very high91.7Very high1 Ų155.5 Ų55.51%0.00529%0.289CS..Hα-helixtrans-63.3-40.5176.4-62.3169.4000110.8V183 L184 E190 R191 I201 F232 F236 Y278V183-I187 HydrophobicContact CG1-CD1 3.91Å; V183-I187 HydrophobicContact CG1-CG1 4.43Å; V183-I187 WeakPolarHBondContact O-CG1 3.49Å; V183-I187 PolarHBondContact O-N 2.72Å; L184-I187 PolarHBondContact O-N 3.45Å; I187-E190 PolarHBondContact O-N 3.31Å; I187-R191 WeakPolarHBondContact O-CG 3.24Å; I187-R191 PolarHBondContact O-N 3.47Å; I187-I201 HydrophobicContact CG1-CD1 3.77Å; I187-F232 HydrophobicContact CD1-CE2 4.45Å; I187-F232 HydrophobicContact CD1-CZ 4.13Å; I187-F236 HydrophobicContact CD1-CD2 4.05Å; I187-F236 HydrophobicContact CD1-CE2 4.02Å; I187-F236 HydrophobicContact CG2-CE2 4.16Å; I187-Y278 HydrophobicContact CD1-CE2 4.18Å; I187-Y278 HydrophobicContact CG1-CE2 4.23Å
188E93.4Very high91.7Very high83 Ų8350.2 Ų50.239%0.38827%0.27SS..Hα-helixtrans-62-42.8175.7-172.7175-170.400112.1L184 K185 L186 E190 R191 N192 F243L184-E188 PolarHBondContact O-N 3.3Å; K185-E188 PolarHBondContact O-N 3.34Å; L186-E188 VanDerWaalsContact C-N 3.32Å; L186-E188 PolarHBondContact O-N 3.02Å; E188-E190 VanDerWaalsContact C-N 3.33Å; E188-E190 PolarHBondContact O-N 2.79Å; E188-R191 WeakPolarHBondContact O-CB 3.44Å; E188-R191 PolarHBondContact O-N 2.77Å; E188-N192 PolarHBondContact O-N 3.11Å; E188-N192 PolarHBondContact O-ND2 2.86Å; E188-F243 HydrophobicContact CG-CD2 4.21Å; E188-F243 HydrophobicContact CG-CE2 4.24Å
189R91.9Very high91.6Very high101 Ų10157.4 Ų57.438%0.38129%0.294SS..Hα-helixtrans-60.9-41174.4-71.9172.867.3-165.5-2.7112.1K185 L186 N192 G193 E194 I196K185-R189 VanDerWaalsContact O-CG 3.3Å; K185-R189 WeakPolarHBondContact O-CG 3.48Å; K185-R189 PolarHBondContact O-N 3.05Å; L186-R189 PolarHBondContact O-N 3.5Å; R189-N192 CarbonylContact O-C 3.52Å; R189-N192 PolarHBondContact O-N 3.17Å; R189-G193 PolarHBondContact O-N 2.78Å; R189-E194 HydrophobicContact CB-CB 4.21Å; R189-E194 HydrophobicContact CB-CG 4.45Å; R189-E194 IonicContact CZ-OE2 3.36Å; R189-E194 IonicContact NE-OE1 2.91Å; R189-E194 IonicContact NE-OE2 3.1Å; R189-E194 PolarHBondContact NE-OE2 3.5Å; R189-E194 IonicContact NH2-OE2 2.82Å; R189-E194 PolarHBondContact NH2-OE2 3.03Å; R189-E194 WeakPolarHBondContact O-CB 3.48Å; R189-E194 PolarHBondContact O-N 3.49Å; R189-I196 HydrophobicContact CB-CG2 4.39Å
190E93.3Very high91.5Very high44 Ų4458 Ų5821%0.20630%0.297CS..Hα-helixtrans-64.7-39.9174.7-168-165.1-130.400112.2L186 I187 E188 N192 G193 E194 I196 R274 Y278L186-E190 PolarHBondContact O-N 2.9Å; I187-E190 PolarHBondContact O-N 3.31Å; E188-E190 VanDerWaalsContact C-N 3.33Å; E188-E190 PolarHBondContact O-N 2.79Å; E190-N192 PolarHBondContact O-N 2.81Å; E190-G193 WeakPolarHBondContact O-CA 3.4Å; E190-G193 PolarHBondContact O-N 3.09Å; E190-E194 WeakPolarHBondContact CA-O 3.43Å; E190-I196 HydrophobicContact CB-CD1 3.72Å; E190-I196 HydrophobicContact CB-CG1 3.87Å; E190-I196 HydrophobicContact CB-CG2 4.13Å; E190-I196 HydrophobicContact CG-CD1 4.06Å; E190-I196 HydrophobicContact CG-CG1 3.94Å; E190-R274 IonicContact OE2-CZ 3.4Å; E190-R274 IonicContact OE2-NE 2.88Å; E190-R274 PolarHBondContact OE2-NE 2.68Å; E190-R274 IonicContact OE2-NH2 3.55Å; E190-Y278 PolarHBondContact OE2-OH 3.25Å; E190-Y278 VanDerWaalsContact OE2-OH 3.08Å
191R92.8Very high91.5Very high10 Ų1057.6 Ų57.64%0.03830%0.295CS..Hα-helixtrans-60.9-31.1173.6-73.7174.4173.2157.23.1112.5I187 E188 G193 T240 F243 R267 E271I187-R191 WeakPolarHBondContact O-CG 3.24Å; I187-R191 PolarHBondContact O-N 3.47Å; E188-R191 WeakPolarHBondContact O-CB 3.44Å; E188-R191 PolarHBondContact O-N 2.77Å; R191-G193 PolarHBondContact O-N 3.08Å; R191-T240 PolarHBondContact NH1-OG1 3.49Å; R191-T240 VanDerWaalsContact NH1-OG1 3.09Å; R191-T240 VanDerWaalsContact NH2-CG2 3.25Å; R191-T240 PolarHBondContact NH2-OG1 2.69Å; R191-F243 HydrophobicContact CB-CE1 3.94Å; R191-F243 HydrophobicContact CB-CE2 4.24Å; R191-F243 HydrophobicContact CB-CZ 3.67Å; R191-F243 HydrophobicContact CG-CE1 4.38Å; R191-R267 PolarHBondContact O-NH1 3.27Å; R191-R267 PolarHBondContact O-NH2 3.5Å; R191-E271 IonicContact CZ-OE1 3.71Å; R191-E271 IonicContact CZ-OE2 3.56Å; R191-E271 IonicContact NE-OE1 2.76Å; R191-E271 PolarHBondContact NE-OE1 3.42Å; R191-E271 IonicContact NE-OE2 2.75Å; R191-E271 VanDerWaalsContact NH2-CD 3.29Å; R191-E271 IonicContact NH2-OE1 3.41Å; R191-E271 PolarHBondContact NH2-OE1 3.5Å; R191-E271 VanDerWaalsContact NH2-OE1 3.11Å; R191-E271 IonicContact NH2-OE2 3.52Å; R191-E271 PolarHBondContact NH2-OE2 2.61Å
192N92.3Very high91.4Very high100 Ų10055.7 Ų55.754%0.53529%0.289SS..THydrogen-bonded Turntrans-81.12.2173.8-64.7-32000113.6E188 R189 E190E188-N192 PolarHBondContact O-N 3.11Å; E188-N192 PolarHBondContact O-ND2 2.86Å; R189-N192 CarbonylContact O-C 3.52Å; R189-N192 PolarHBondContact O-N 3.17Å; E190-N192 PolarHBondContact O-N 2.81Å
193G89.1Confident91.2Very high65 Ų6555.9 Ų55.967%0.6729%0.291SS*.THydrogen-bonded Turntrans93.97.6174.500000115R189 E190 R191R189-G193 PolarHBondContact O-N 2.78Å; E190-G193 WeakPolarHBondContact O-CA 3.4Å; E190-G193 PolarHBondContact O-N 3.09Å; R191-G193 PolarHBondContact O-N 3.08Å
194E92.1Very high91.1Very high85 Ų8555.9 Ų55.940%0.39729%0.291SS..  trans-78.1144.8175.8-61.7-179.5-13400111.9R189 E190 I196R189-E194 HydrophobicContact CB-CB 4.21Å; R189-E194 HydrophobicContact CB-CG 4.45Å; R189-E194 IonicContact CZ-OE2 3.36Å; R189-E194 IonicContact NE-OE1 2.91Å; R189-E194 IonicContact NE-OE2 3.1Å; R189-E194 PolarHBondContact NE-OE2 3.5Å; R189-E194 IonicContact NH2-OE2 2.82Å; R189-E194 PolarHBondContact NH2-OE2 3.03Å; R189-E194 WeakPolarHBondContact O-CB 3.48Å; R189-E194 PolarHBondContact O-N 3.49Å; E190-E194 WeakPolarHBondContact CA-O 3.43Å; E194-I196 PolarHBondContact O-N 3.03Å
195T88.4Confident91Very high143 Ų14355.7 Ų55.788%0.87729%0.29SS*.  trans-77.1123.7172.754.40000110.7
196I91.4Very high90.9Very high29 Ų2955 Ų5515%0.14929%0.288CS..  trans-116.5160.4-179.861.9157.9000112.4L186 R189 E190 E194 T198 I201L186-I196 HydrophobicContact CD2-CG2 4.24Å; R189-I196 HydrophobicContact CB-CG2 4.39Å; E190-I196 HydrophobicContact CB-CD1 3.72Å; E190-I196 HydrophobicContact CB-CG1 3.87Å; E190-I196 HydrophobicContact CB-CG2 4.13Å; E190-I196 HydrophobicContact CG-CD1 4.06Å; E190-I196 HydrophobicContact CG-CG1 3.94Å; E194-I196 PolarHBondContact O-N 3.03Å; I196-T198 HydrophobicContact CD1-CG2 4.44Å; I196-T198 HydrophobicContact CG1-CG2 4.29Å; I196-T198 PolarHBondContact O-N 3.3Å; I196-I201 HydrophobicContact CD1-CD1 3.49Å; I196-I201 VanDerWaalsContact CD1-CD1 3.49Å
197N88.1Confident90.8Very high70 Ų7054.5 Ų54.537%0.37429%0.286SS..  trans-85.391.4172.5-172.1-9.3000110.7R199 L200N197-R199 PolarHBondContact O-N 3.15Å; N197-R199 VanDerWaalsContact O-N 3.14Å; N197-R199 WeakPolarHBondContact OD1-CB 3.21Å; N197-R199 PolarHBondContact OD1-N 2.91Å; N197-L200 HydrophobicContact CB-CD1 4.05Å; N197-L200 HydrophobicContact CB-CG 4.18Å; N197-L200 PolarHBondContact O-N 3.43Å; N197-L200 VanDerWaalsContact O-N 3.12Å
198T89.4Confident90.6Very high47 Ų4754.5 Ų54.529%0.28829%0.286SS..Hα-helixtrans-60.3-22.4-178.456.90000113.9I196 L200 I201 S202 V277 Y278I196-T198 HydrophobicContact CD1-CG2 4.44Å; I196-T198 HydrophobicContact CG1-CG2 4.29Å; I196-T198 PolarHBondContact O-N 3.3Å; T198-L200 VanDerWaalsContact C-N 3.3Å; T198-L200 PolarHBondContact O-N 3.43Å; T198-I201 PolarHBondContact O-N 3.5Å; T198-S202 PolarHBondContact O-N 3.04Å; T198-V277 HydrophobicContact CG2-CG1 4.3Å; T198-Y278 HydrophobicContact CG2-CD1 3.97Å; T198-Y278 HydrophobicContact CG2-CE1 4.24Å
199R88.9Confident90.4Very high209 Ų20951.4 Ų51.479%0.78927%0.273SS*.Hα-helixtrans-65.4-33.4176.8-61-176.6-179.11731.3112.4N197 I201 G203N197-R199 PolarHBondContact O-N 3.15Å; N197-R199 VanDerWaalsContact O-N 3.14Å; N197-R199 WeakPolarHBondContact OD1-CB 3.21Å; N197-R199 PolarHBondContact OD1-N 2.91Å; R199-I201 VanDerWaalsContact C-N 3.33Å; R199-G203 PolarHBondContact O-N 2.88Å
200L89.3Confident90.1Very high12 Ų1248.2 Ų48.26%0.06326%0.262CS..Hα-helixtrans-65.1-41.5177.3-63.9177.6000110.8E113 L116 K117 T120 N197 T198 V204E113-L200 HydrophobicContact CG-CD1 3.73Å; L116-L200 HydrophobicContact CB-CB 4.39Å; L116-L200 HydrophobicContact CB-CD1 4.37Å; K117-L200 HydrophobicContact CG-CD1 4.08Å; K117-L200 HydrophobicContact CG-CD2 3.87Å; T120-L200 HydrophobicContact CG2-CD2 4.49Å; T120-L200 WeakPolarHBondContact CG2-O 3.07Å; N197-L200 HydrophobicContact CB-CD1 4.05Å; N197-L200 HydrophobicContact CB-CG 4.18Å; N197-L200 PolarHBondContact O-N 3.43Å; N197-L200 VanDerWaalsContact O-N 3.12Å; T198-L200 VanDerWaalsContact C-N 3.3Å; T198-L200 PolarHBondContact O-N 3.43Å; L200-V204 WeakPolarHBondContact O-CG2 3.47Å; L200-V204 PolarHBondContact O-N 2.94Å
201I91.5Very high89.8Confident0 Ų046.1 Ų46.10%025%0.252CS..Hα-helixtrans-67.4-50.1177.9-56.4178.3000110.1V183 L186 I187 I196 T198 R199 G203 V204 V205 Y278V183-I201 HydrophobicContact CG1-CB 4.45Å; V183-I201 HydrophobicContact CG1-CG1 4.19Å; V183-I201 HydrophobicContact CG1-CG2 3.78Å; L186-I201 HydrophobicContact CB-CD1 4.28Å; I187-I201 HydrophobicContact CG1-CD1 3.77Å; I196-I201 HydrophobicContact CD1-CD1 3.49Å; I196-I201 VanDerWaalsContact CD1-CD1 3.49Å; T198-I201 PolarHBondContact O-N 3.5Å; R199-I201 VanDerWaalsContact C-N 3.33Å; I201-G203 VanDerWaalsContact C-N 3.28Å; I201-G203 PolarHBondContact O-N 3.22Å; I201-V204 PolarHBondContact O-N 3.14Å; I201-V204 VanDerWaalsContact O-N 3.15Å; I201-V205 HydrophobicContact CG2-CG2 4.14Å; I201-V205 WeakPolarHBondContact O-CG2 3.14Å; I201-V205 PolarHBondContact O-N 3.12Å; I201-Y278 HydrophobicContact CB-CD2 4.14Å; I201-Y278 HydrophobicContact CB-CG 4.29Å; I201-Y278 HydrophobicContact CD1-CD2 4.49Å; I201-Y278 HydrophobicContact CD1-CE2 4.25Å; I201-Y278 HydrophobicContact CG2-CD2 3.37Å; I201-Y278 HydrophobicContact CG2-CE2 3.86Å; I201-Y278 HydrophobicContact CG2-CG 3.98Å
202S90.4Very high89.1Confident49 Ų4945.6 Ų45.634%0.34325%0.25SS..Hα-helixtrans-57.9-40.4178.9-178.90000112T198 V205 Q206T198-S202 PolarHBondContact O-N 3.04Å; S202-V205 PolarHBondContact O-N 2.93Å; S202-Q206 VanDerWaalsContact O-CB 3.27Å; S202-Q206 WeakPolarHBondContact O-CB 3.37Å; S202-Q206 PolarHBondContact O-N 3.13Å
203G88.9Confident88.2Confident7 Ų742.3 Ų42.37%0.07223%0.232CC..Hα-helixtrans-63.2-41.9176.100000113.5R199 I201 S207R199-G203 PolarHBondContact O-N 2.88Å; I201-G203 VanDerWaalsContact C-N 3.28Å; I201-G203 PolarHBondContact O-N 3.22Å; G203-S207 PolarHBondContact O-N 3.03Å
204V91.1Very high87Confident0 Ų042.2 Ų42.20%022%0.217CC..Hα-helixtrans-67.9-46.4175.2176.50000111L116 Y119 T120 V179 V183 L200 I201 Q206 S207 Y208L116-V204 HydrophobicContact CD2-CG2 3.98Å; Y119-V204 HydrophobicContact CD1-CG2 4.04Å; T120-V204 HydrophobicContact CG2-CG2 3.78Å; V179-V204 HydrophobicContact CG1-CB 4.49Å; V179-V204 HydrophobicContact CG1-CG1 3.62Å; V179-V204 HydrophobicContact CG1-CG2 3.92Å; V183-V204 HydrophobicContact CG2-CB 4.07Å; V183-V204 HydrophobicContact CG2-CG1 3.95Å; V183-V204 HydrophobicContact CG2-CG2 4.1Å; L200-V204 WeakPolarHBondContact O-CG2 3.47Å; L200-V204 PolarHBondContact O-N 2.94Å; I201-V204 PolarHBondContact O-N 3.14Å; I201-V204 VanDerWaalsContact O-N 3.15Å; V204-Q206 VanDerWaalsContact C-N 3.33Å; V204-Q206 PolarHBondContact O-N 3.22Å; V204-S207 WeakPolarHBondContact O-CA 3.36Å; V204-S207 VanDerWaalsContact O-CB 3.3Å; V204-S207 WeakPolarHBondContact O-CB 3.4Å; V204-S207 PolarHBondContact O-N 3.43Å; V204-S207 VanDerWaalsContact O-N 3.1Å; V204-Y208 HydrophobicContact CG1-CD1 3.79Å; V204-Y208 HydrophobicContact CG1-CE1 3.35Å; V204-Y208 HydrophobicContact CG1-CE2 4.46Å; V204-Y208 WeakPolarHBondContact O-CD1 3.43Å; V204-Y208 PolarHBondContact O-N 3.09Å
205V91.1Very high85.5Confident9 Ų943.7 Ų43.76%0.05522%0.223CC..Hα-helixtrans-59.6-45178.2168.60000110.8I201 S202 S207 Y208 V209 Y228 F232 L279I201-V205 HydrophobicContact CG2-CG2 4.14Å; I201-V205 WeakPolarHBondContact O-CG2 3.14Å; I201-V205 PolarHBondContact O-N 3.12Å; S202-V205 PolarHBondContact O-N 2.93Å; V205-S207 VanDerWaalsContact C-N 3.3Å; V205-S207 PolarHBondContact O-N 3.31Å; V205-Y208 PolarHBondContact O-N 3.14Å; V205-Y208 VanDerWaalsContact O-N 3.14Å; V205-V209 HydrophobicContact CG1-CG2 4.43Å; V205-V209 WeakPolarHBondContact O-CG2 3.49Å; V205-V209 PolarHBondContact O-N 3.41Å; V205-Y228 HydrophobicContact CG1-CD2 4.14Å; V205-Y228 HydrophobicContact CG1-CE2 3.69Å; V205-Y228 HydrophobicContact CG2-CE2 4.29Å; V205-F232 HydrophobicContact CG2-CE1 4.45Å; V205-L279 HydrophobicContact CG2-CD2 4.37Å
206Q88.9Confident83.9Confident81 Ų8146.4 Ų46.438%0.37923%0.226SC..Hα-helixtrans-60-40.8175.3-178.7172.811.300111.7S202 V204 E210S202-Q206 VanDerWaalsContact O-CB 3.27Å; S202-Q206 WeakPolarHBondContact O-CB 3.37Å; S202-Q206 PolarHBondContact O-N 3.13Å; V204-Q206 VanDerWaalsContact C-N 3.33Å; V204-Q206 PolarHBondContact O-N 3.22Å; Q206-E210 HydrophobicContact CG-CG 4.44Å; Q206-E210 PolarHBondContact NE2-OE1 3.25Å; Q206-E210 WeakPolarHBondContact O-CB 3.37Å; Q206-E210 WeakPolarHBondContact O-CG 3.49Å; Q206-E210 PolarHBondContact O-N 3.48Å
207S90.6Very high82.3Confident0 Ų049.2 Ų49.20%024%0.242CC..Hα-helixtrans-59.9-47.5173.6-177.90000111.3Y119 G203 V204 V205 V209 E210 L211Y119-S207 PolarHBondContact OH-OG 3.41Å; G203-S207 PolarHBondContact O-N 3.03Å; V204-S207 WeakPolarHBondContact O-CA 3.36Å; V204-S207 VanDerWaalsContact O-CB 3.3Å; V204-S207 WeakPolarHBondContact O-CB 3.4Å; V204-S207 PolarHBondContact O-N 3.43Å; V204-S207 VanDerWaalsContact O-N 3.1Å; V205-S207 VanDerWaalsContact C-N 3.3Å; V205-S207 PolarHBondContact O-N 3.31Å; S207-V209 VanDerWaalsContact C-N 3.32Å; S207-V209 PolarHBondContact O-N 3.39Å; S207-E210 PolarHBondContact O-N 3.26Å; S207-L211 WeakPolarHBondContact O-CB 3.38Å; S207-L211 WeakPolarHBondContact O-CD1 3.37Å; S207-L211 WeakPolarHBondContact O-CG 3.37Å; S207-L211 PolarHBondContact O-N 3.26Å
208Y90.2Very high80.6Confident0 Ų048.8 Ų48.80%025%0.248CC..Hα-helixtrans-67.2-35.6-175.8-76.233.3000111.8Y119 F172 N176 V179 T180 V204 V205 V227 F232Y119-Y208 HydrophobicContact CE1-CE1 4.4Å; F172-Y208 HydrophobicContact CD2-CD1 4.14Å; F172-Y208 AromaticContact CD2-CE1 3.78Å; F172-Y208 HydrophobicContact CD2-CE1 3.78Å; F172-Y208 AromaticContact CE2-CD1 3.65Å; F172-Y208 HydrophobicContact CE2-CD1 3.65Å; F172-Y208 HydrophobicContact CE2-CD2 4.06Å; F172-Y208 AromaticContact CE2-CE1 3.4Å; F172-Y208 HydrophobicContact CE2-CE1 3.4Å; F172-Y208 VanDerWaalsContact CE2-CE1 3.4Å; F172-Y208 AromaticContact CE2-CE2 3.83Å; F172-Y208 HydrophobicContact CE2-CE2 3.83Å; F172-Y208 AromaticContact CE2-CG 3.99Å; F172-Y208 HydrophobicContact CE2-CG 3.99Å; F172-Y208 AromaticContact CE2-CZ 3.5Å; F172-Y208 VanDerWaalsContact CE2-CZ 3.5Å; F172-Y208 HydrophobicContact CZ-CE2 4.41Å; N176-Y208 PolarHBondContact O-OH 3.08Å; V179-Y208 HydrophobicContact CG1-CE1 4.35Å; V179-Y208 WeakPolarHBondContact CG1-OH 3.45Å; T180-Y208 PolarHBondContact OG1-OH 2.93Å; T180-Y208 VanDerWaalsContact OG1-OH 3.12Å; V204-Y208 HydrophobicContact CG1-CD1 3.79Å; V204-Y208 HydrophobicContact CG1-CE1 3.35Å; V204-Y208 HydrophobicContact CG1-CE2 4.46Å; V204-Y208 WeakPolarHBondContact O-CD1 3.43Å; V204-Y208 PolarHBondContact O-N 3.09Å; V205-Y208 PolarHBondContact O-N 3.14Å; V205-Y208 VanDerWaalsContact O-N 3.14Å; Y208-V227 WeakPolarHBondContact O-CB 3.03Å; Y208-F232 HydrophobicContact CD2-CB 3.73Å; Y208-F232 HydrophobicContact CE2-CB 3.98Å
209V88.3Confident78.8Confident19 Ų1951.9 Ų51.912%0.11526%0.258CS..Hα-helixtrans-67-51.6172.7172.60000110.3V205 S207 L211 G212 P223 L225 Y228 H280V205-V209 HydrophobicContact CG1-CG2 4.43Å; V205-V209 WeakPolarHBondContact O-CG2 3.49Å; V205-V209 PolarHBondContact O-N 3.41Å; S207-V209 VanDerWaalsContact C-N 3.32Å; S207-V209 PolarHBondContact O-N 3.39Å; V209-L211 VanDerWaalsContact C-N 3.26Å; V209-L211 PolarHBondContact O-N 3.01Å; V209-G212 PolarHBondContact O-N 2.87Å; V209-P223 HydrophobicContact CG1-CB 4.29Å; V209-P223 HydrophobicContact CG1-CG 3.8Å; V209-P223 WeakPolarHBondContact O-CB 3.13Å; V209-L225 HydrophobicContact CG1-CD2 4.05Å; V209-L225 HydrophobicContact CG2-CD2 4.2Å; V209-Y228 HydrophobicContact CG2-CD2 4.03Å; V209-Y228 HydrophobicContact CG2-CG 4.05Å; V209-H280 HydrophobicContact CG2-CB 4.43Å
210E86.6Confident77.3Confident33 Ų3343.8 Ų43.815%0.15424%0.236CC..Hα-helixtrans-66.1-23.8-177.9-73.7-170.7-153.800114.1W123 R127 Y160 Q206 S207 G212W123-E210 HydrophobicContact CH2-CB 4.45Å; W123-E210 HydrophobicContact CZ2-CB 3.96Å; R127-E210 IonicContact CZ-OE1 3.65Å; R127-E210 IonicContact CZ-OE2 3.21Å; R127-E210 VanDerWaalsContact NE-CD 3.31Å; R127-E210 IonicContact NE-OE1 3.88Å; R127-E210 PolarHBondContact NE-OE1 3.28Å; R127-E210 IonicContact NE-OE2 3.08Å; R127-E210 PolarHBondContact NE-OE2 3.4Å; R127-E210 IonicContact NH2-OE1 2.67Å; R127-E210 PolarHBondContact NH2-OE1 3.2Å; R127-E210 IonicContact NH2-OE2 3.31Å; Y160-E210 PolarHBondContact OH-OE2 2.94Å; Q206-E210 HydrophobicContact CG-CG 4.44Å; Q206-E210 PolarHBondContact NE2-OE1 3.25Å; Q206-E210 WeakPolarHBondContact O-CB 3.37Å; Q206-E210 WeakPolarHBondContact O-CG 3.49Å; Q206-E210 PolarHBondContact O-N 3.48Å; S207-E210 PolarHBondContact O-N 3.26Å; E210-G212 VanDerWaalsContact C-N 3.3Å
211L85.9Confident75.5Confident0 Ų053.4 Ų53.40%028%0.277CS..THydrogen-bonded Turntrans-77-13.1177.6-72.9170.9000114.2W123 L164 W167 R168 F172 S207 V209 L213 V227W123-L211 HydrophobicContact CH2-CD2 3.95Å; W123-L211 HydrophobicContact CH2-CG 4.06Å; W123-L211 HydrophobicContact CZ3-CD2 4.03Å; W123-L211 HydrophobicContact CZ3-CG 4.38Å; L164-L211 HydrophobicContact CB-CD2 4.46Å; L164-L211 HydrophobicContact CD2-CD2 4.42Å; L164-L211 WeakPolarHBondContact O-CD2 3.38Å; W167-L211 HydrophobicContact CB-CD2 4.28Å; W167-L211 HydrophobicContact CG-CD2 4.23Å; R168-L211 HydrophobicContact CB-CD2 4.19Å; F172-L211 HydrophobicContact CB-CD1 4.01Å; F172-L211 HydrophobicContact CD2-CD1 3.68Å; F172-L211 HydrophobicContact CE2-CD1 4.3Å; F172-L211 HydrophobicContact CG-CD1 3.85Å; S207-L211 WeakPolarHBondContact O-CB 3.38Å; S207-L211 WeakPolarHBondContact O-CD1 3.37Å; S207-L211 WeakPolarHBondContact O-CG 3.37Å; S207-L211 PolarHBondContact O-N 3.26Å; V209-L211 VanDerWaalsContact C-N 3.26Å; V209-L211 PolarHBondContact O-N 3.01Å; L211-L213 PolarHBondContact O-N 3.25Å; L211-V227 HydrophobicContact CB-CG1 4.24Å
212G79.3Confident73.8Confident0 Ų055.6 Ų55.60%030%0.299CS..  trans-77.8106.3171.900000110.6V209 E210 P223 T224V209-G212 PolarHBondContact O-N 2.87Å; E210-G212 VanDerWaalsContact C-N 3.3Å; G212-P223 CarbonylContact O-C 3.55Å; G212-P223 WeakPolarHBondContact O-CA 3.34Å; G212-P223 WeakPolarHBondContact O-CB 3.47Å; G212-T224 VanDerWaalsContact CA-O 3.22Å; G212-T224 WeakPolarHBondContact CA-O 3.45Å; G212-T224 WeakPolarHBondContact CA-OG1 3.41Å; G212-T224 PolarHBondContact O-N 2.88Å; G212-T224 PolarHBondContact O-OG1 3.37Å
213L72.1Confident72.6Confident30 Ų3056.5 Ų56.516%0.15730%0.304CS..  trans-104.2146.4179.2-62.7169.8000109.9L164 V165 L211 E215 T224L164-L213 HydrophobicContact CB-CD1 4.05Å; L164-L213 HydrophobicContact CD1-CD2 3.9Å; V165-L213 HydrophobicContact CG2-CD1 3.41Å; V165-L213 VanDerWaalsContact CG2-CD1 3.41Å; L211-L213 PolarHBondContact O-N 3.25Å; L213-E215 PolarHBondContact O-N 3.42Å; L213-T224 PolarHBondContact N-OG1 3.17Å; L213-T224 PolarHBondContact O-OG1 2.96Å; L213-T224 VanDerWaalsContact O-OG1 3.11Å
214N64.5Low71.9Confident63 Ų6357.5 Ų57.534%0.33731%0.309SS..  trans-76.2100168.2-83.5-51.5000108.8E216 A220 G222 T224N214-E216 VanDerWaalsContact C-N 3.26Å; N214-E216 PolarHBondContact O-N 2.96Å; N214-A220 HydrophobicContact CB-CB 4.18Å; N214-G222 PolarHBondContact ND2-O 3.5Å; N214-T224 HydrophobicContact CB-CG2 4.29Å; N214-T224 VanDerWaalsContact CG-CG2 3.41Å; N214-T224 WeakPolarHBondContact OD1-CG2 3.39Å
215E60.2Low71.5Confident116 Ų11659.7 Ų59.754%0.54232%0.321SS..SBendtrans-73.4-18.8178.5-65.7-173.5179.300112.8R168 L213R168-E215 IonicContact CZ-OE1 3.81Å; R168-E215 IonicContact NH1-OE1 2.63Å; R168-E215 PolarHBondContact NH1-OE1 3.43Å; R168-E215 IonicContact NH2-OE1 3.41Å; R168-E215 PolarHBondContact NH2-OE1 2.88Å; L213-E215 PolarHBondContact O-N 3.42Å
216E54.8Low71.2Confident200 Ų20062.1 Ų62.194%0.93534%0.338SS*.SBendtrans-90.2-26.2-178.4-60.7-167.2154.600113.9N214N214-E216 VanDerWaalsContact C-N 3.26Å; N214-E216 PolarHBondContact O-N 2.96Å
217D57.7Low71.1Confident88 Ų8858.6 Ų58.647%0.47132%0.322SS..  trans-137.296.4179.1-167.7-7.2000110.3F219 A220D217-F219 PolarHBondContact O-N 2.76Å; D217-F219 PolarHBondContact OD1-N 2.92Å; D217-A220 HydrophobicContact CB-CB 3.89Å; D217-A220 PolarHBondContact O-N 3.31Å; D217-A220 VanDerWaalsContact O-N 3.11Å
218A53Low71Confident62 Ų6258.6 Ų58.651%0.51232%0.322SS..THydrogen-bonded Turntrans-62.6-11.2-17800000113.6
219F51.7Low70.9Confident111 Ų11162 Ų6249%0.48734%0.337SS..THydrogen-bonded Turntrans-109.4-3.9178.8-62.6-78.3000113.9R146 C149 D217 K221R146-F219 HydrophobicContact CG-CE1 4.24Å; R146-F219 HydrophobicContact CG-CZ 4.03Å; C149-F219 HydrophobicContact CB-CE2 4.09Å; C149-F219 HydrophobicContact CB-CZ 4.15Å; D217-F219 PolarHBondContact O-N 2.76Å; D217-F219 PolarHBondContact OD1-N 2.92Å; F219-K221 PolarHBondContact O-N 3.06Å
220A57.8Low70.9Confident40 Ų4066.9 Ų66.933%0.33136%0.358SS..  trans-64.5120.5175.700000110.2N214 D217 G222N214-A220 HydrophobicContact CB-CB 4.18Å; D217-A220 HydrophobicContact CB-CB 3.89Å; D217-A220 PolarHBondContact O-N 3.31Å; D217-A220 VanDerWaalsContact O-N 3.11Å; A220-G222 PolarHBondContact O-N 3.37Å
221K50.7Low71Confident213 Ų21368.4 Ų68.493%0.92636%0.363SS*.  trans-79.1112.7179.9-73.7-177.3177.5178.70110.4F219F219-K221 PolarHBondContact O-N 3.06Å
222G57Low71.4Confident46 Ų4668.5 Ų68.547%0.47436%0.364SS..SBendtrans129.4148.2169.100000112.6N214 A220N214-G222 PolarHBondContact ND2-O 3.5Å; A220-G222 PolarHBondContact O-N 3.37Å
223P64.1Low72Confident68 Ų6868.6 Ų68.644%0.44236%0.364SS..  trans-67.9145.3176.825-29.7000112V209 G212V209-P223 HydrophobicContact CG1-CB 4.29Å; V209-P223 HydrophobicContact CG1-CG 3.8Å; V209-P223 WeakPolarHBondContact O-CB 3.13Å; G212-P223 CarbonylContact O-C 3.55Å; G212-P223 WeakPolarHBondContact O-CA 3.34Å; G212-P223 WeakPolarHBondContact O-CB 3.47Å
224T74.4Confident72.9Confident29 Ų2970.7 Ų70.718%0.17838%0.38CS..  trans-75137.2162.550.10000108.7G212 L213 N214 S226G212-T224 VanDerWaalsContact CA-O 3.22Å; G212-T224 WeakPolarHBondContact CA-O 3.45Å; G212-T224 WeakPolarHBondContact CA-OG1 3.41Å; G212-T224 PolarHBondContact O-N 2.88Å; G212-T224 PolarHBondContact O-OG1 3.37Å; L213-T224 PolarHBondContact N-OG1 3.17Å; L213-T224 PolarHBondContact O-OG1 2.96Å; L213-T224 VanDerWaalsContact O-OG1 3.11Å; N214-T224 HydrophobicContact CB-CG2 4.29Å; N214-T224 VanDerWaalsContact CG-CG2 3.41Å; N214-T224 WeakPolarHBondContact OD1-CG2 3.39Å; T224-S226 PolarHBondContact O-N 2.99Å; T224-S226 VanDerWaalsContact O-N 3.12Å; T224-S226 PolarHBondContact OG1-OG 3.01Å
225L83.3Confident74.3Confident46 Ų4671.6 Ų71.624%0.24138%0.383CS..THydrogen-bonded Turntrans-75.34.6176.4-64.5173.8000112.8V209 V227 Y228 K229V209-L225 HydrophobicContact CG1-CD2 4.05Å; V209-L225 HydrophobicContact CG2-CD2 4.2Å; L225-V227 PolarHBondContact O-N 3.49Å; L225-Y228 PolarHBondContact O-N 3.39Å; L225-K229 HydrophobicContact CB-CG 4.04Å; L225-K229 WeakPolarHBondContact O-CB 3.41Å; L225-K229 WeakPolarHBondContact O-CG 3.29Å; L225-K229 PolarHBondContact O-N 3.41Å
226S84.1Confident76Confident60 Ų6066.1 Ų66.142%0.4236%0.357SS..Hα-helixtrans-55.8-47.1-171.254.90000113.2T224 K229 E230T224-S226 PolarHBondContact O-N 2.99Å; T224-S226 VanDerWaalsContact O-N 3.12Å; T224-S226 PolarHBondContact OG1-OG 3.01Å; S226-K229 PolarHBondContact O-N 3.28Å; S226-E230 WeakPolarHBondContact O-CB 3.41Å; S226-E230 PolarHBondContact O-N 2.88Å
227V86.2Confident77.9Confident6 Ų657.4 Ų57.44%0.03632%0.316CS..Hα-helixtrans-66.4-42.9-179.8177.60000111F172 Y208 L211 L225 Y231F172-V227 HydrophobicContact CE1-CG1 3.84Å; F172-V227 HydrophobicContact CE2-CG1 3.98Å; F172-V227 HydrophobicContact CZ-CG1 3.39Å; Y208-V227 WeakPolarHBondContact O-CB 3.03Å; L211-V227 HydrophobicContact CB-CG1 4.24Å; L225-V227 PolarHBondContact O-N 3.49Å; V227-Y231 HydrophobicContact CG1-CD2 4Å; V227-Y231 WeakPolarHBondContact O-CB 3.47Å; V227-Y231 WeakPolarHBondContact O-CD2 3.48Å; V227-Y231 PolarHBondContact O-N 2.95Å; V227-Y231 VanDerWaalsContact O-N 3.08Å
228Y90.2Very high79.6Confident0 Ų057.1 Ų57.10%032%0.318CS..Hα-helixtrans-62-46.7174.7173.4-97.7000111.9V205 V209 L225 F232 E233 H280 T283V205-Y228 HydrophobicContact CG1-CD2 4.14Å; V205-Y228 HydrophobicContact CG1-CE2 3.69Å; V205-Y228 HydrophobicContact CG2-CE2 4.29Å; V209-Y228 HydrophobicContact CG2-CD2 4.03Å; V209-Y228 HydrophobicContact CG2-CG 4.05Å; L225-Y228 PolarHBondContact O-N 3.39Å; Y228-F232 HydrophobicContact CD2-CB 4.49Å; Y228-F232 AromaticContact CD2-CD1 3.99Å; Y228-F232 HydrophobicContact CD2-CD1 3.99Å; Y228-F232 AromaticContact CE2-CD1 3.36Å; Y228-F232 HydrophobicContact CE2-CD1 3.36Å; Y228-F232 AromaticContact CE2-CE1 3.85Å; Y228-F232 HydrophobicContact CE2-CE1 3.85Å; Y228-F232 HydrophobicContact CE2-CG 4.31Å; Y228-F232 AromaticContact CZ-CD1 3.81Å; Y228-F232 WeakPolarHBondContact O-CA 3.5Å; Y228-F232 WeakPolarHBondContact O-CB 3.43Å; Y228-F232 PolarHBondContact O-N 3.18Å; Y228-F232 VanDerWaalsContact O-N 3.1Å; Y228-E233 HydrophobicContact CD1-CB 4.29Å; Y228-E233 HydrophobicContact CE1-CB 3.97Å; Y228-E233 HydrophobicContact CE1-CG 4.22Å; Y228-E233 PolarHBondContact O-N 3.42Å; Y228-H280 HydrophobicContact CD1-CB 4.39Å; Y228-H280 HydrophobicContact CE1-CB 3.8Å; Y228-H280 HydrophobicContact CE2-CB 4.25Å; Y228-H280 PolarHBondContact OH-N 3.03Å; Y228-T283 VanDerWaalsContact CE1-OG1 3.26Å; Y228-T283 WeakPolarHBondContact CE1-OG1 3.34Å; Y228-T283 PolarHBondContact OH-OG1 2.81Å
229K88Confident81.6Confident72 Ų7256.7 Ų56.731%0.31331%0.307SS..Iπ-helixtrans-62.4-51.3-179.4-64.9-136.7168.5-163.70111.9L225 S226 E233 C234 E286L225-K229 HydrophobicContact CB-CG 4.04Å; L225-K229 WeakPolarHBondContact O-CB 3.41Å; L225-K229 WeakPolarHBondContact O-CG 3.29Å; L225-K229 PolarHBondContact O-N 3.41Å; S226-K229 PolarHBondContact O-N 3.28Å; K229-E233 WeakPolarHBondContact CD-OE2 3.46Å; K229-E233 VanDerWaalsContact CE-OE2 3.24Å; K229-E233 WeakPolarHBondContact CE-OE2 3.16Å; K229-E233 WeakPolarHBondContact CG-OE2 3.42Å; K229-E233 IonicContact NZ-OE2 3.87Å; K229-E233 PolarHBondContact O-N 3.23Å; K229-C234 PolarHBondContact O-N 3.39Å; K229-C234 PolarHBondContact O-SG 3.27Å; K229-E286 IonicContact NZ-OE1 2.88Å
230E88.3Confident83.6Confident122 Ų12251.5 Ų51.557%0.5728%0.284SS*.Iπ-helixtrans-70.2-45.9-173.3-173.9-175.4165.200112.7S226S226-E230 WeakPolarHBondContact O-CB 3.41Å; S226-E230 PolarHBondContact O-N 2.88Å
231Y88.4Confident85.4Confident65 Ų6551.9 Ų51.926%0.25528%0.279SS..Iπ-helixtrans-98.1-13.5-170-64.9-85.8000114.4F172 N176 T180 V227F172-Y231 HydrophobicContact CE1-CD1 4.39Å; F172-Y231 HydrophobicContact CE1-CD2 4.11Å; F172-Y231 HydrophobicContact CE1-CE2 4.32Å; F172-Y231 HydrophobicContact CE1-CG 4.16Å; F172-Y231 HydrophobicContact CZ-CD1 4.26Å; F172-Y231 AromaticContact CZ-CD2 3.89Å; F172-Y231 HydrophobicContact CZ-CD2 3.89Å; F172-Y231 AromaticContact CZ-CG 3.74Å; F172-Y231 HydrophobicContact CZ-CG 3.74Å; N176-Y231 WeakPolarHBondContact ND2-CD1 3.36Å; N176-Y231 WeakPolarHBondContact ND2-CE1 3.26Å; T180-Y231 WeakPolarHBondContact CG2-O 3.38Å; T180-Y231 PolarHBondContact OG1-O 3.49Å; T180-Y231 VanDerWaalsContact OG1-O 3.09Å; V227-Y231 HydrophobicContact CG1-CD2 4Å; V227-Y231 WeakPolarHBondContact O-CB 3.47Å; V227-Y231 WeakPolarHBondContact O-CD2 3.48Å; V227-Y231 PolarHBondContact O-N 2.95Å; V227-Y231 VanDerWaalsContact O-N 3.08Å
232F93.2Very high87.5Confident2 Ų249.8 Ų49.81%0.00927%0.266CS..Iπ-helixtrans-128.4-61.5179.5176.6-94.5000112.8T180 V183 L184 I187 V205 Y208 Y228 C234 Q235 F236 L279T180-F232 HydrophobicContact CG2-CD2 4.39Å; V183-F232 HydrophobicContact CB-CE2 4.38Å; V183-F232 HydrophobicContact CG1-CD2 4.46Å; V183-F232 HydrophobicContact CG1-CE2 3.6Å; V183-F232 HydrophobicContact CG1-CZ 4.31Å; L184-F232 HydrophobicContact CD2-CE2 4.16Å; I187-F232 HydrophobicContact CD1-CE2 4.45Å; I187-F232 HydrophobicContact CD1-CZ 4.13Å; V205-F232 HydrophobicContact CG2-CE1 4.45Å; Y208-F232 HydrophobicContact CD2-CB 3.73Å; Y208-F232 HydrophobicContact CE2-CB 3.98Å; Y228-F232 HydrophobicContact CD2-CB 4.49Å; Y228-F232 AromaticContact CD2-CD1 3.99Å; Y228-F232 HydrophobicContact CD2-CD1 3.99Å; Y228-F232 AromaticContact CE2-CD1 3.36Å; Y228-F232 HydrophobicContact CE2-CD1 3.36Å; Y228-F232 AromaticContact CE2-CE1 3.85Å; Y228-F232 HydrophobicContact CE2-CE1 3.85Å; Y228-F232 HydrophobicContact CE2-CG 4.31Å; Y228-F232 AromaticContact CZ-CD1 3.81Å; Y228-F232 WeakPolarHBondContact O-CA 3.5Å; Y228-F232 WeakPolarHBondContact O-CB 3.43Å; Y228-F232 PolarHBondContact O-N 3.18Å; Y228-F232 VanDerWaalsContact O-N 3.1Å; F232-C234 PolarHBondContact O-N 2.98Å; F232-Q235 PolarHBondContact O-N 3.14Å; F232-F236 HydrophobicContact CD1-CB 4.44Å; F232-F236 HydrophobicContact CE1-CB 4.04Å; F232-F236 HydrophobicContact CE1-CD1 4.45Å; F232-F236 HydrophobicContact CE1-CG 4.15Å; F232-F236 HydrophobicContact CE2-CB 4.39Å; F232-F236 HydrophobicContact CZ-CB 4.02Å; F232-F236 HydrophobicContact CZ-CD2 4.23Å; F232-F236 HydrophobicContact CZ-CG 4.06Å; F232-F236 VanDerWaalsContact O-CB 3.28Å; F232-F236 WeakPolarHBondContact O-CB 3.33Å; F232-F236 PolarHBondContact O-N 3.22Å; F232-L279 HydrophobicContact CE1-CD2 3.69Å; F232-L279 HydrophobicContact CZ-CD2 3.73Å
233E92.8Very high89.4Confident1 Ų148.9 Ų48.91%0.00525%0.249CC..Iπ-helixtrans-57.2-48.1-170.1-168.2171.8-133.600112.3Y228 K229 Q235 F236 L237 T283Y228-E233 HydrophobicContact CD1-CB 4.29Å; Y228-E233 HydrophobicContact CE1-CB 3.97Å; Y228-E233 HydrophobicContact CE1-CG 4.22Å; Y228-E233 PolarHBondContact O-N 3.42Å; K229-E233 WeakPolarHBondContact CD-OE2 3.46Å; K229-E233 VanDerWaalsContact CE-OE2 3.24Å; K229-E233 WeakPolarHBondContact CE-OE2 3.16Å; K229-E233 WeakPolarHBondContact CG-OE2 3.42Å; K229-E233 IonicContact NZ-OE2 3.87Å; K229-E233 PolarHBondContact O-N 3.23Å; E233-Q235 PolarHBondContact O-N 3.16Å; E233-F236 PolarHBondContact O-N 2.98Å; E233-L237 HydrophobicContact CG-CD1 4.03Å; E233-L237 HydrophobicContact CG-CG 4.37Å; E233-L237 WeakPolarHBondContact O-CB 3.33Å; E233-L237 VanDerWaalsContact O-CG 3.25Å; E233-L237 WeakPolarHBondContact O-CG 3.31Å; E233-L237 PolarHBondContact O-N 3.47Å; E233-T283 HydrophobicContact CG-CG2 4.15Å; E233-T283 WeakPolarHBondContact OE1-CA 3.31Å; E233-T283 VanDerWaalsContact OE1-CB 3.26Å; E233-T283 WeakPolarHBondContact OE1-CB 3.42Å; E233-T283 PolarHBondContact OE1-N 3.43Å; E233-T283 PolarHBondContact OE1-OG1 3.5Å
234C91.6Very high90.9Very high74 Ų7445.7 Ų45.750%0.523%0.228SC..Hα-helixtrans-58.2-45.1178.8-74.40000113K229 F232 T238K229-C234 PolarHBondContact O-N 3.39Å; K229-C234 PolarHBondContact O-SG 3.27Å; F232-C234 PolarHBondContact O-N 2.98Å; C234-T238 WeakPolarHBondContact O-CB 3.37Å; C234-T238 PolarHBondContact O-N 3.49Å; C234-T238 VanDerWaalsContact O-N 3.16Å; C234-T238 PolarHBondContact O-OG1 2.92Å
235Q93Very high91.9Very high83 Ų8346.5 Ų46.539%0.38823%0.233SC..Hα-helixtrans-71.6-40.8179.1-17163.752.500111L184 F232 E233 L237 T238 D239L184-Q235 HydrophobicContact CD1-CB 4.21Å; L184-Q235 HydrophobicContact CD1-CG 3.5Å; F232-Q235 PolarHBondContact O-N 3.14Å; E233-Q235 PolarHBondContact O-N 3.16Å; Q235-L237 PolarHBondContact O-N 2.93Å; Q235-T238 PolarHBondContact O-N 3.31Å; Q235-D239 PolarHBondContact NE2-OD1 3.28Å; Q235-D239 WeakPolarHBondContact O-CB 3.43Å; Q235-D239 PolarHBondContact O-N 2.73Å
236F95.1Very high92.4Very high1 Ų150 Ų500%0.00424%0.243CC..Hα-helixtrans-58.1-47.2176.1168.1-108.8000112L184 I187 F232 E233 T238 D239 T240 L279 T283 L287L184-F236 HydrophobicContact CD2-CB 3.81Å; L184-F236 HydrophobicContact CD2-CD2 3.96Å; L184-F236 HydrophobicContact CD2-CG 4.4Å; I187-F236 HydrophobicContact CD1-CD2 4.05Å; I187-F236 HydrophobicContact CD1-CE2 4.02Å; I187-F236 HydrophobicContact CG2-CE2 4.16Å; F232-F236 HydrophobicContact CD1-CB 4.44Å; F232-F236 HydrophobicContact CE1-CB 4.04Å; F232-F236 HydrophobicContact CE1-CD1 4.45Å; F232-F236 HydrophobicContact CE1-CG 4.15Å; F232-F236 HydrophobicContact CE2-CB 4.39Å; F232-F236 HydrophobicContact CZ-CB 4.02Å; F232-F236 HydrophobicContact CZ-CD2 4.23Å; F232-F236 HydrophobicContact CZ-CG 4.06Å; F232-F236 VanDerWaalsContact O-CB 3.28Å; F232-F236 WeakPolarHBondContact O-CB 3.33Å; F232-F236 PolarHBondContact O-N 3.22Å; E233-F236 PolarHBondContact O-N 2.98Å; F236-T238 VanDerWaalsContact C-N 3.34Å; F236-T238 PolarHBondContact O-N 3.32Å; F236-D239 PolarHBondContact O-N 3.2Å; F236-T240 VanDerWaalsContact O-CB 3.25Å; F236-T240 WeakPolarHBondContact O-CB 3.38Å; F236-T240 PolarHBondContact O-N 3.21Å; F236-T240 PolarHBondContact O-OG1 3.49Å; F236-L279 HydrophobicContact CE1-CD1 3.78Å; F236-L279 HydrophobicContact CZ-CD1 3.72Å; F236-T283 HydrophobicContact CD1-CG2 4.16Å; F236-T283 HydrophobicContact CE1-CG2 3.96Å; F236-L287 HydrophobicContact CE1-CD1 3.72Å; F236-L287 HydrophobicContact CE1-CD2 3.93Å; F236-L287 HydrophobicContact CE1-CG 4.31Å; F236-L287 HydrophobicContact CZ-CD1 3.93Å; F236-L287 HydrophobicContact CZ-CD2 4.02Å
237L95.1Very high92.9Very high16 Ų1648.5 Ų48.58%0.08423%0.229CC..Hα-helixtrans-64.1-40.3177.4-68.1175.1000111.6E233 Q235 T240 E241 E286 L287E233-L237 HydrophobicContact CG-CD1 4.03Å; E233-L237 HydrophobicContact CG-CG 4.37Å; E233-L237 WeakPolarHBondContact O-CB 3.33Å; E233-L237 VanDerWaalsContact O-CG 3.25Å; E233-L237 WeakPolarHBondContact O-CG 3.31Å; E233-L237 PolarHBondContact O-N 3.47Å; Q235-L237 PolarHBondContact O-N 2.93Å; L237-T240 PolarHBondContact O-N 3.48Å; L237-E241 PolarHBondContact O-N 2.89Å; L237-E286 HydrophobicContact CD1-CB 4.03Å; L237-L287 HydrophobicContact CD2-CB 3.92Å; L237-L287 HydrophobicContact CD2-CD1 3.96Å
238T94.4Very high93.3Very high82 Ų8248.2 Ų48.250%0.50323%0.228SC..Hα-helixtrans-64.5-46.1177.9-57.70000111.9C234 Q235 F236 T240 E241 R242C234-T238 WeakPolarHBondContact O-CB 3.37Å; C234-T238 PolarHBondContact O-N 3.49Å; C234-T238 VanDerWaalsContact O-N 3.16Å; C234-T238 PolarHBondContact O-OG1 2.92Å; Q235-T238 PolarHBondContact O-N 3.31Å; F236-T238 VanDerWaalsContact C-N 3.34Å; F236-T238 PolarHBondContact O-N 3.32Å; T238-T240 VanDerWaalsContact C-N 3.31Å; T238-T240 PolarHBondContact O-N 3.4Å; T238-E241 PolarHBondContact O-N 2.9Å; T238-R242 WeakPolarHBondContact O-CB 3.19Å; T238-R242 PolarHBondContact O-N 2.78Å
239D93.9Very high93.5Very high54 Ų5451 Ų5129%0.28924%0.244SC..Hα-helixtrans-68.1-34.8178.2-76.26.3000111.4L184 Q235 F236 R242 F243L184-D239 WeakPolarHBondContact CD1-OD2 3.39Å; Q235-D239 PolarHBondContact NE2-OD1 3.28Å; Q235-D239 WeakPolarHBondContact O-CB 3.43Å; Q235-D239 PolarHBondContact O-N 2.73Å; F236-D239 PolarHBondContact O-N 3.2Å; D239-R242 PolarHBondContact O-N 3.21Å; D239-F243 VanDerWaalsContact O-CB 3.29Å; D239-F243 WeakPolarHBondContact O-CB 3.45Å; D239-F243 PolarHBondContact O-N 3.41Å
240T95.1Very high93.8Very high1 Ų152.2 Ų52.21%0.00625%0.251CS..Hα-helixtrans-64.4-46.4174-58.60000112.1R191 F236 L237 T238 R242 F243 Y244 L287R191-T240 PolarHBondContact NH1-OG1 3.49Å; R191-T240 VanDerWaalsContact NH1-OG1 3.09Å; R191-T240 VanDerWaalsContact NH2-CG2 3.25Å; R191-T240 PolarHBondContact NH2-OG1 2.69Å; F236-T240 VanDerWaalsContact O-CB 3.25Å; F236-T240 WeakPolarHBondContact O-CB 3.38Å; F236-T240 PolarHBondContact O-N 3.21Å; F236-T240 PolarHBondContact O-OG1 3.49Å; L237-T240 PolarHBondContact O-N 3.48Å; T238-T240 VanDerWaalsContact C-N 3.31Å; T238-T240 PolarHBondContact O-N 3.4Å; T240-R242 VanDerWaalsContact C-N 3.31Å; T240-R242 PolarHBondContact O-N 3.42Å; T240-F243 PolarHBondContact O-N 2.92Å; T240-Y244 HydrophobicContact CG2-CD2 3.55Å; T240-Y244 HydrophobicContact CG2-CE2 3.62Å; T240-Y244 WeakPolarHBondContact O-CD2 3.19Å; T240-Y244 PolarHBondContact O-N 2.98Å; T240-L287 HydrophobicContact CG2-CD1 3.77Å
241E95.2Very high94.1Very high48 Ų4848.4 Ų48.422%0.22423%0.233CC..Hα-helixtrans-59-44.4174165.5159.3-156.300110.9L237 T238 T245 K290 V294 K298L237-E241 PolarHBondContact O-N 2.89Å; T238-E241 PolarHBondContact O-N 2.9Å; E241-T245 VanDerWaalsContact O-CB 3.22Å; E241-T245 WeakPolarHBondContact O-CB 3.49Å; E241-T245 PolarHBondContact O-N 2.84Å; E241-T245 PolarHBondContact O-OG1 3.48Å; E241-K290 IonicContact OE2-NZ 3.73Å; E241-K290 PolarHBondContact OE2-NZ 3.13Å; E241-V294 HydrophobicContact CB-CG2 4.11Å; E241-V294 HydrophobicContact CG-CG2 3.68Å; E241-K298 IonicContact OE1-NZ 3.02Å; E241-K298 PolarHBondContact OE1-NZ 3.4Å
242R95.1Very high94.3Very high170 Ų17046.7 Ų46.764%0.64223%0.228SC*.Hα-helixtrans-65.1-41.1178.9-170.1179.5-177.8-1720.7112.6T238 D239 T240 R246T238-R242 WeakPolarHBondContact O-CB 3.19Å; T238-R242 PolarHBondContact O-N 2.78Å; D239-R242 PolarHBondContact O-N 3.21Å; T240-R242 VanDerWaalsContact C-N 3.31Å; T240-R242 PolarHBondContact O-N 3.42Å; R242-R246 PolarHBondContact O-N 2.88Å
243F95.7Very high94.3Very high26 Ų2653.8 Ų53.811%0.11426%0.261CS..Hα-helixtrans-62.7-55.2177.6179.2-89.7000110.7E188 R191 D239 T240 T245 R246 E247E188-F243 HydrophobicContact CG-CD2 4.21Å; E188-F243 HydrophobicContact CG-CE2 4.24Å; R191-F243 HydrophobicContact CB-CE1 3.94Å; R191-F243 HydrophobicContact CB-CE2 4.24Å; R191-F243 HydrophobicContact CB-CZ 3.67Å; R191-F243 HydrophobicContact CG-CE1 4.38Å; D239-F243 VanDerWaalsContact O-CB 3.29Å; D239-F243 WeakPolarHBondContact O-CB 3.45Å; D239-F243 PolarHBondContact O-N 3.41Å; T240-F243 PolarHBondContact O-N 2.92Å; F243-T245 VanDerWaalsContact C-N 3.34Å; F243-T245 PolarHBondContact O-N 3.44Å; F243-R246 PolarHBondContact O-N 3.39Å; F243-E247 PolarHBondContact O-N 3.49Å
244Y96.3Very high94.3Very high1 Ų161.2 Ų61.20%0.00430%0.296CS..Hα-helixtrans-70.8-27.5-177.3-75-54.6000113.4T240 R246 S248 R267 E271 V294 L295T240-Y244 HydrophobicContact CG2-CD2 3.55Å; T240-Y244 HydrophobicContact CG2-CE2 3.62Å; T240-Y244 WeakPolarHBondContact O-CD2 3.19Å; T240-Y244 PolarHBondContact O-N 2.98Å; Y244-R246 VanDerWaalsContact C-N 3.32Å; Y244-S248 WeakPolarHBondContact O-CB 3.33Å; Y244-S248 PolarHBondContact O-N 2.87Å; Y244-S248 PolarHBondContact O-OG 3.01Å; Y244-R267 HydrophobicContact CE1-CB 3.9Å; Y244-R267 HydrophobicContact CE1-CG 3.77Å; Y244-E271 HydrophobicContact CE2-CG 3.79Å; Y244-E271 WeakPolarHBondContact OH-CG 3.5Å; Y244-E271 PolarHBondContact OH-OE1 3.35Å; Y244-V294 VanDerWaalsContact C-CG1 3.49Å; Y244-L295 HydrophobicContact CD1-CD1 4.4Å; Y244-L295 HydrophobicContact CD1-CD2 3.87Å; Y244-L295 HydrophobicContact CG-CD1 4.46Å; Y244-L295 HydrophobicContact CG-CD2 4.06Å; Y244-L295 HydrophobicContact CG-CG 4.37Å
245T94.8Very high94.4Very high46 Ų4660.5 Ų60.528%0.28229%0.287SS..Hα-helixtrans-64.2-41.7173.2-61.40000110.5E241 F243 S248 T249 V294E241-T245 VanDerWaalsContact O-CB 3.22Å; E241-T245 WeakPolarHBondContact O-CB 3.49Å; E241-T245 PolarHBondContact O-N 2.84Å; E241-T245 PolarHBondContact O-OG1 3.48Å; F243-T245 VanDerWaalsContact C-N 3.34Å; F243-T245 PolarHBondContact O-N 3.44Å; T245-S248 PolarHBondContact O-OG 3.36Å; T245-T249 WeakPolarHBondContact O-CB 3.48Å; T245-T249 PolarHBondContact O-N 3.42Å; T245-T249 PolarHBondContact O-OG1 2.99Å; T245-V294 VanDerWaalsContact N-CG1 3.26Å; T245-V294 VanDerWaalsContact OG1-CG1 3.28Å; T245-V294 WeakPolarHBondContact OG1-CG1 3.48Å
246R94.8Very high94.5Very high120 Ų12060.3 Ų60.345%0.45329%0.293SS..Hα-helixtrans-69.1-52.1176.9-169-174.4-41.3167.214.9111.4R242 F243 Y244 S248 T249 E250R242-R246 PolarHBondContact O-N 2.88Å; F243-R246 PolarHBondContact O-N 3.39Å; Y244-R246 VanDerWaalsContact C-N 3.32Å; R246-S248 PolarHBondContact O-N 2.7Å; R246-T249 PolarHBondContact O-N 2.98Å; R246-E250 HydrophobicContact CG-CG 4.46Å; R246-E250 WeakPolarHBondContact CG-OE1 3.28Å; R246-E250 WeakPolarHBondContact O-CB 3.48Å; R246-E250 WeakPolarHBondContact O-CG 3.11Å; R246-E250 PolarHBondContact O-N 2.91Å
247E94.7Very high94.4Very high28 Ų2861.1 Ų61.113%0.13130%0.298CS..Hα-helixtrans-59.4-45.4-178.3-176.9177.9-134.100111.6F243 T249 F251 K263 R267F243-E247 PolarHBondContact O-N 3.49Å; E247-T249 PolarHBondContact O-N 3.18Å; E247-F251 WeakPolarHBondContact O-CB 3.25Å; E247-F251 PolarHBondContact O-N 2.64Å; E247-K263 WeakPolarHBondContact OE1-CE 3.43Å; E247-K263 IonicContact OE1-NZ 3.79Å; E247-K263 PolarHBondContact OE1-NZ 3.5Å; E247-R267 IonicContact OE1-CZ 3.82Å; E247-R267 IonicContact OE1-NE 3.74Å; E247-R267 PolarHBondContact OE1-NE 2.86Å; E247-R267 IonicContact OE1-NH2 3.9Å; E247-R267 PolarHBondContact OE1-NH2 3.11Å; E247-R267 IonicContact OE2-CZ 3.25Å; E247-R267 IonicContact OE2-NE 3.59Å; E247-R267 PolarHBondContact OE2-NE 3.12Å; E247-R267 IonicContact OE2-NH2 3.56Å
248S94.8Very high94.4Very high1 Ų161.1 Ų61.11%0.00730%0.299CS..Hα-helixtrans-63.2-43.9-179.355.10000112.4Y244 T245 R246 F251 L252 Y260 H299Y244-S248 WeakPolarHBondContact O-CB 3.33Å; Y244-S248 PolarHBondContact O-N 2.87Å; Y244-S248 PolarHBondContact O-OG 3.01Å; T245-S248 PolarHBondContact O-OG 3.36Å; R246-S248 PolarHBondContact O-N 2.7Å; S248-F251 PolarHBondContact O-N 3.4Å; S248-L252 WeakPolarHBondContact O-CB 3.49Å; S248-L252 WeakPolarHBondContact O-CG 3.25Å; S248-L252 PolarHBondContact O-N 2.91Å; S248-Y260 WeakPolarHBondContact CB-OH 3.35Å; S248-H299 WeakPolarHBondContact CB-NE2 3.13Å; S248-H299 PolarHBondContact OG-NE2 3.33Å
249T93.4Very high94.4Very high57 Ų5761.1 Ų61.135%0.3529%0.293SS..Hα-helixtrans-68.3-45.6-178.1-55.10000111.4T245 R246 E247 Q253T245-T249 WeakPolarHBondContact O-CB 3.48Å; T245-T249 PolarHBondContact O-N 3.42Å; T245-T249 PolarHBondContact O-OG1 2.99Å; R246-T249 PolarHBondContact O-N 2.98Å; E247-T249 PolarHBondContact O-N 3.18Å; T249-Q253 VanDerWaalsContact O-CG 3.31Å; T249-Q253 WeakPolarHBondContact O-CG 3.49Å; T249-Q253 PolarHBondContact O-N 3.49Å
250E94.6Very high94.5Very high99 Ų9958.8 Ų58.846%0.46328%0.28SS..Hα-helixtrans-64.1-41.2176.6-72.7174.4-173.500111.5R246 Q253 Q254R246-E250 HydrophobicContact CG-CG 4.46Å; R246-E250 WeakPolarHBondContact CG-OE1 3.28Å; R246-E250 WeakPolarHBondContact O-CB 3.48Å; R246-E250 WeakPolarHBondContact O-CG 3.11Å; R246-E250 PolarHBondContact O-N 2.91Å; E250-Q253 PolarHBondContact O-N 3.16Å; E250-Q254 PolarHBondContact O-N 2.87Å
251F94.4Very high94.5Very high41 Ų4158.7 Ų58.718%0.1828%0.28CS..Hα-helixtrans-68.3-43.3-179-166.2-86.5000112.2E247 S248 Q253 Q254 N255 E259 Y260 K263E247-F251 WeakPolarHBondContact O-CB 3.25Å; E247-F251 PolarHBondContact O-N 2.64Å; S248-F251 PolarHBondContact O-N 3.4Å; F251-Q253 VanDerWaalsContact C-N 3.27Å; F251-Q253 PolarHBondContact O-N 3.24Å; F251-Q254 PolarHBondContact O-N 3.47Å; F251-N255 HydrophobicContact CD1-CB 3.92Å; F251-N255 HydrophobicContact CE1-CB 3.55Å; F251-N255 HydrophobicContact CZ-CB 3.93Å; F251-N255 WeakPolarHBondContact O-CB 3.43Å; F251-N255 PolarHBondContact O-N 3.28Å; F251-N255 PolarHBondContact O-ND2 2.83Å; F251-E259 HydrophobicContact CE1-CB 4.29Å; F251-E259 HydrophobicContact CZ-CB 4.45Å; F251-Y260 HydrophobicContact CB-CD2 4.47Å; F251-Y260 AromaticContact CD1-CD2 3.81Å; F251-Y260 HydrophobicContact CD1-CD2 3.81Å; F251-Y260 HydrophobicContact CD1-CG 4.37Å; F251-Y260 HydrophobicContact CG-CD2 4.48Å; F251-K263 HydrophobicContact CD1-CD 4.36Å; F251-K263 HydrophobicContact CD2-CD 3.6Å; F251-K263 HydrophobicContact CE1-CD 4.28Å; F251-K263 HydrophobicContact CE2-CD 3.51Å; F251-K263 HydrophobicContact CG-CD 4.02Å; F251-K263 HydrophobicContact CZ-CB 4.49Å; F251-K263 HydrophobicContact CZ-CD 3.86Å
252L93.3Very high94.5Very high30 Ų3060.3 Ų60.316%0.15729%0.286CS..Hα-helixtrans-65.5-27177.7-78.7168.2000113.1S248 Q254 V257 Y260 H299 I302S248-L252 WeakPolarHBondContact O-CB 3.49Å; S248-L252 WeakPolarHBondContact O-CG 3.25Å; S248-L252 PolarHBondContact O-N 2.91Å; L252-Q254 VanDerWaalsContact C-N 3.32Å; L252-V257 HydrophobicContact CD2-CG2 4.22Å; L252-Y260 HydrophobicContact CD1-CD1 4.23Å; L252-Y260 HydrophobicContact CD1-CD2 4.42Å; L252-Y260 HydrophobicContact CD1-CE1 4.07Å; L252-Y260 HydrophobicContact CD1-CE2 4.29Å; L252-Y260 HydrophobicContact CD1-CG 4.39Å; L252-Y260 HydrophobicContact CD2-CD1 3.64Å; L252-Y260 HydrophobicContact CD2-CD2 4.09Å; L252-Y260 HydrophobicContact CD2-CE1 4.31Å; L252-Y260 HydrophobicContact CD2-CG 3.48Å; L252-Y260 VanDerWaalsContact CD2-CG 3.48Å; L252-Y260 HydrophobicContact CG-CD1 4.06Å; L252-Y260 HydrophobicContact CG-CD2 3.84Å; L252-Y260 HydrophobicContact CG-CE1 4.35Å; L252-Y260 HydrophobicContact CG-CE2 4.16Å; L252-Y260 HydrophobicContact CG-CG 3.77Å; L252-H299 HydrophobicContact CD1-CB 4.22Å; L252-I302 HydrophobicContact CD1-CD1 4.13Å
253Q92.5Very high94.4Very high151 Ų15155.1 Ų55.171%0.70627%0.268SS*.Hα-helixtrans-71.2-28.1174.5-76.2175.66.900113.1T249 E250 F251T249-Q253 VanDerWaalsContact O-CG 3.31Å; T249-Q253 WeakPolarHBondContact O-CG 3.49Å; T249-Q253 PolarHBondContact O-N 3.49Å; E250-Q253 PolarHBondContact O-N 3.16Å; F251-Q253 VanDerWaalsContact C-N 3.27Å; F251-Q253 PolarHBondContact O-N 3.24Å
254Q93.1Very high94.4Very high156 Ų15653.9 Ų53.973%0.72926%0.263SS*.Hα-helixtrans-107-17.4-171.3-63.8176.812.500113.3E250 F251 L252E250-Q254 PolarHBondContact O-N 2.87Å; F251-Q254 PolarHBondContact O-N 3.47Å; L252-Q254 VanDerWaalsContact C-N 3.32Å
255N94.1Very high94.4Very high60 Ų6057.3 Ų57.332%0.32128%0.279SS..SBendtrans-134.3155.3-169.9-58.9-85.4000112F251F251-N255 HydrophobicContact CD1-CB 3.92Å; F251-N255 HydrophobicContact CE1-CB 3.55Å; F251-N255 HydrophobicContact CZ-CB 3.93Å; F251-N255 WeakPolarHBondContact O-CB 3.43Å; F251-N255 PolarHBondContact O-N 3.28Å; F251-N255 PolarHBondContact O-ND2 2.83Å
256P93.3Very high94.4Very high78 Ų7857.2 Ų57.251%0.50628%0.283SS..  trans-60.7150.3171.9-21.733.5000112.7T258 E259 Y260P256-T258 PolarHBondContact O-N 3.39Å; P256-E259 PolarHBondContact O-N 3.18Å; P256-E259 VanDerWaalsContact O-N 3.16Å; P256-Y260 PolarHBondContact O-N 3.41Å; P256-Y260 VanDerWaalsContact O-N 3.14Å
257V94.1Very high94.4Very high18 Ų1852.8 Ų52.811%0.10927%0.266CS..Hα-helixtrans-59.7-32.4178.4179.30000111.8L252 E259 Y260 M261 I302 F303 E306L252-V257 HydrophobicContact CD2-CG2 4.22Å; V257-E259 PolarHBondContact O-N 2.89Å; V257-Y260 WeakPolarHBondContact O-CB 3.26Å; V257-Y260 PolarHBondContact O-N 2.88Å; V257-M261 WeakPolarHBondContact O-CG 3.37Å; V257-M261 PolarHBondContact O-N 3.08Å; V257-I302 HydrophobicContact CG1-CG2 4.39Å; V257-I302 HydrophobicContact CG2-CG2 3.45Å; V257-I302 VanDerWaalsContact CG2-CG2 3.45Å; V257-F303 HydrophobicContact CG1-CD1 4.07Å; V257-F303 HydrophobicContact CG1-CE1 4.22Å; V257-E306 HydrophobicContact CB-CB 4.09Å; V257-E306 HydrophobicContact CB-CG 3.79Å; V257-E306 HydrophobicContact CG1-CB 3.95Å; V257-E306 HydrophobicContact CG1-CG 3.94Å; V257-E306 HydrophobicContact CG2-CB 4.27Å; V257-E306 HydrophobicContact CG2-CG 4.36Å
258T94.1Very high94.4Very high16 Ų1652.5 Ų52.510%0.09827%0.265CS..Hα-helixtrans-61.5-41.7176.647.50000113.5P256 M261 K262 L310 D318P256-T258 PolarHBondContact O-N 3.39Å; T258-M261 HydrophobicContact CG2-CE 4.11Å; T258-M261 PolarHBondContact O-N 3.33Å; T258-K262 PolarHBondContact O-N 3.04Å; T258-L310 HydrophobicContact CG2-CD1 4.49Å; T258-L310 HydrophobicContact CG2-CD2 3.73Å; T258-D318 HydrophobicContact CG2-CB 4.21Å
259E94.4Very high94.4Very high82 Ų8256.1 Ų56.138%0.38328%0.284SS..Hα-helixtrans-72-35.3173.9-68.4-55.6127.800111.4F251 P256 V257 M261 K262 K263F251-E259 HydrophobicContact CE1-CB 4.29Å; F251-E259 HydrophobicContact CZ-CB 4.45Å; P256-E259 PolarHBondContact O-N 3.18Å; P256-E259 VanDerWaalsContact O-N 3.16Å; V257-E259 PolarHBondContact O-N 2.89Å; E259-M261 VanDerWaalsContact C-N 3.33Å; E259-M261 PolarHBondContact O-N 3.48Å; E259-K262 PolarHBondContact O-N 3.1Å; E259-K262 IonicContact OE1-NZ 2.92Å; E259-K262 PolarHBondContact OE1-NZ 3.37Å; E259-K262 IonicContact OE2-NZ 2.86Å; E259-K263 PolarHBondContact O-N 3.08Å
260Y96.3Very high94.4Very high5 Ų555.8 Ų55.82%0.0228%0.279CS..Hα-helixtrans-60.1-42.9173.2175.2-104.3000111.9S248 F251 L252 P256 V257 K262 K263 A264 L295 H299 F303S248-Y260 WeakPolarHBondContact CB-OH 3.35Å; F251-Y260 HydrophobicContact CB-CD2 4.47Å; F251-Y260 AromaticContact CD1-CD2 3.81Å; F251-Y260 HydrophobicContact CD1-CD2 3.81Å; F251-Y260 HydrophobicContact CD1-CG 4.37Å; F251-Y260 HydrophobicContact CG-CD2 4.48Å; L252-Y260 HydrophobicContact CD1-CD1 4.23Å; L252-Y260 HydrophobicContact CD1-CD2 4.42Å; L252-Y260 HydrophobicContact CD1-CE1 4.07Å; L252-Y260 HydrophobicContact CD1-CE2 4.29Å; L252-Y260 HydrophobicContact CD1-CG 4.39Å; L252-Y260 HydrophobicContact CD2-CD1 3.64Å; L252-Y260 HydrophobicContact CD2-CD2 4.09Å; L252-Y260 HydrophobicContact CD2-CE1 4.31Å; L252-Y260 HydrophobicContact CD2-CG 3.48Å; L252-Y260 VanDerWaalsContact CD2-CG 3.48Å; L252-Y260 HydrophobicContact CG-CD1 4.06Å; L252-Y260 HydrophobicContact CG-CD2 3.84Å; L252-Y260 HydrophobicContact CG-CE1 4.35Å; L252-Y260 HydrophobicContact CG-CE2 4.16Å; L252-Y260 HydrophobicContact CG-CG 3.77Å; P256-Y260 PolarHBondContact O-N 3.41Å; P256-Y260 VanDerWaalsContact O-N 3.14Å; V257-Y260 WeakPolarHBondContact O-CB 3.26Å; V257-Y260 PolarHBondContact O-N 2.88Å; Y260-K262 VanDerWaalsContact C-N 3.34Å; Y260-K262 PolarHBondContact O-N 3.28Å; Y260-K263 CarbonylContact O-C 3.53Å; Y260-K263 PolarHBondContact O-N 3.12Å; Y260-K263 VanDerWaalsContact O-N 3.13Å; Y260-A264 HydrophobicContact CE1-CB 4.45Å; Y260-A264 WeakPolarHBondContact O-CB 3.26Å; Y260-A264 PolarHBondContact O-N 2.68Å; Y260-L295 WeakPolarHBondContact CE1-O 3.25Å; Y260-L295 WeakPolarHBondContact OH-CA 3.4Å; Y260-L295 PolarHBondContact OH-O 2.88Å; Y260-H299 PolarHBondContact OH-CD2 3.16Å; Y260-F303 AromaticContact CD1-CE1 3.76Å; Y260-F303 HydrophobicContact CD1-CE1 3.76Å; Y260-F303 AromaticContact CD1-CZ 3.98Å; Y260-F303 HydrophobicContact CD1-CZ 3.98Å; Y260-F303 AromaticContact CE1-CE1 3.68Å; Y260-F303 HydrophobicContact CE1-CE1 3.68Å; Y260-F303 AromaticContact CE1-CZ 3.73Å; Y260-F303 HydrophobicContact CE1-CZ 3.73Å
261M94.9Very high94.4Very high0 Ų051.3 Ų51.30%026%0.258CS..Hα-helixtrans-59.9-42177.5-72.5-169.9-69.900112.5V257 T258 E259 K263 A264 E265 F303 L310 D318 R321 M322 L325V257-M261 WeakPolarHBondContact O-CG 3.37Å; V257-M261 PolarHBondContact O-N 3.08Å; T258-M261 HydrophobicContact CG2-CE 4.11Å; T258-M261 PolarHBondContact O-N 3.33Å; E259-M261 VanDerWaalsContact C-N 3.33Å; E259-M261 PolarHBondContact O-N 3.48Å; M261-K263 VanDerWaalsContact C-N 3.33Å; M261-A264 PolarHBondContact O-N 3.46Å; M261-E265 WeakPolarHBondContact O-CB 3.37Å; M261-E265 PolarHBondContact O-N 2.58Å; M261-F303 HydrophobicContact CG-CE2 4.35Å; M261-F303 HydrophobicContact CG-CZ 4.12Å; M261-L310 HydrophobicContact CE-CD1 4.09Å; M261-D318 HydrophobicContact CE-CB 4.4Å; M261-R321 HydrophobicContact CB-CG 4.36Å; M261-M322 HydrophobicContact CE-CB 4.4Å; M261-M322 HydrophobicContact CE-CE 3.88Å; M261-M322 HydrophobicContact SD-CB 3.55Å; M261-M322 VanDerWaalsContact SD-CB 3.55Å; M261-M322 HydrophobicContact SD-CE 3.62Å; M261-M322 HydrophobicContact SD-CG 3.85Å; M261-L325 HydrophobicContact CB-CD1 3.69Å; M261-L325 HydrophobicContact CG-CD1 3.83Å; M261-L325 HydrophobicContact SD-CD1 4.38Å
262K95.3Very high94.3Very high82 Ų8253.4 Ų53.436%0.35727%0.268SS..Hα-helixtrans-62.6-42.5174.6-66.4173-173.9167.60111.2T258 E259 Y260 E265 A266T258-K262 PolarHBondContact O-N 3.04Å; E259-K262 PolarHBondContact O-N 3.1Å; E259-K262 IonicContact OE1-NZ 2.92Å; E259-K262 PolarHBondContact OE1-NZ 3.37Å; E259-K262 IonicContact OE2-NZ 2.86Å; Y260-K262 VanDerWaalsContact C-N 3.34Å; Y260-K262 PolarHBondContact O-N 3.28Å; K262-E265 PolarHBondContact O-N 2.7Å; K262-A266 WeakPolarHBondContact O-CB 3.26Å; K262-A266 PolarHBondContact O-N 3.43Å
263K94.5Very high94.3Very high60 Ų6058.1 Ų58.126%0.26128%0.284SS..Hα-helixtrans-65.3-43.8177.6-171171.1179.5-178.50111.6E247 F251 E259 Y260 M261 E265 A266 R267E247-K263 WeakPolarHBondContact OE1-CE 3.43Å; E247-K263 IonicContact OE1-NZ 3.79Å; E247-K263 PolarHBondContact OE1-NZ 3.5Å; F251-K263 HydrophobicContact CD1-CD 4.36Å; F251-K263 HydrophobicContact CD2-CD 3.6Å; F251-K263 HydrophobicContact CE1-CD 4.28Å; F251-K263 HydrophobicContact CE2-CD 3.51Å; F251-K263 HydrophobicContact CG-CD 4.02Å; F251-K263 HydrophobicContact CZ-CB 4.49Å; F251-K263 HydrophobicContact CZ-CD 3.86Å; E259-K263 PolarHBondContact O-N 3.08Å; Y260-K263 CarbonylContact O-C 3.53Å; Y260-K263 PolarHBondContact O-N 3.12Å; Y260-K263 VanDerWaalsContact O-N 3.13Å; M261-K263 VanDerWaalsContact C-N 3.33Å; K263-E265 PolarHBondContact O-N 3.03Å; K263-A266 PolarHBondContact O-N 3.13Å; K263-R267 HydrophobicContact CG-CG 4.47Å; K263-R267 WeakPolarHBondContact O-CG 3.14Å; K263-R267 PolarHBondContact O-N 3.18Å
264A95.6Very high94.4Very high1 Ų151.6 Ų51.61%0.00825%0.253CS..Hα-helixtrans-60.8-44.8177.300000111.5Y260 M261 A266 R267 L268Y260-A264 HydrophobicContact CE1-CB 4.45Å; Y260-A264 WeakPolarHBondContact O-CB 3.26Å; Y260-A264 PolarHBondContact O-N 2.68Å; M261-A264 PolarHBondContact O-N 3.46Å; A264-A266 PolarHBondContact O-N 3.37Å; A264-R267 PolarHBondContact O-N 3.32Å; A264-L268 WeakPolarHBondContact O-CG 3.16Å; A264-L268 PolarHBondContact O-N 3.13Å
265E94.6Very high94.4Very high73 Ų7344.5 Ų44.534%0.34122%0.22SC..Hα-helixtrans-58.9-46.9174.3-178.6174-141.900111.9M261 K262 K263 R267 L268 L269 R321 L325M261-E265 WeakPolarHBondContact O-CB 3.37Å; M261-E265 PolarHBondContact O-N 2.58Å; K262-E265 PolarHBondContact O-N 2.7Å; K263-E265 PolarHBondContact O-N 3.03Å; E265-R267 PolarHBondContact O-N 3.23Å; E265-L268 PolarHBondContact O-N 3.24Å; E265-L269 WeakPolarHBondContact O-CG 3.34Å; E265-L269 PolarHBondContact O-N 3.39Å; E265-L269 VanDerWaalsContact O-N 3.15Å; E265-R321 IonicContact OE2-NE 3.13Å; E265-L325 HydrophobicContact CB-CD2 4.32Å
266A95.2Very high94.2Very high43 Ų4348.1 Ų48.136%0.35524%0.235SC..Hα-helixtrans-60.5-44.2176.700000112.2K262 K263 A264 L269 E270K262-A266 WeakPolarHBondContact O-CB 3.26Å; K262-A266 PolarHBondContact O-N 3.43Å; K263-A266 PolarHBondContact O-N 3.13Å; A264-A266 PolarHBondContact O-N 3.37Å; A266-L269 PolarHBondContact O-N 3.18Å; A266-E270 WeakPolarHBondContact O-CG 3.45Å; A266-E270 PolarHBondContact O-N 2.8Å
267R94.7Very high94.2Very high28 Ų2848.7 Ų48.711%0.10624%0.237CC..Hα-helixtrans-64.2-41.8178.7-71.3-55.2-162.5-169.72.6112.8R191 Y244 E247 K263 A264 E265 L269 E270 E271 L295R191-R267 PolarHBondContact O-NH1 3.27Å; R191-R267 PolarHBondContact O-NH2 3.5Å; Y244-R267 HydrophobicContact CE1-CB 3.9Å; Y244-R267 HydrophobicContact CE1-CG 3.77Å; E247-R267 IonicContact OE1-CZ 3.82Å; E247-R267 IonicContact OE1-NE 3.74Å; E247-R267 PolarHBondContact OE1-NE 2.86Å; E247-R267 IonicContact OE1-NH2 3.9Å; E247-R267 PolarHBondContact OE1-NH2 3.11Å; E247-R267 IonicContact OE2-CZ 3.25Å; E247-R267 IonicContact OE2-NE 3.59Å; E247-R267 PolarHBondContact OE2-NE 3.12Å; E247-R267 IonicContact OE2-NH2 3.56Å; K263-R267 HydrophobicContact CG-CG 4.47Å; K263-R267 WeakPolarHBondContact O-CG 3.14Å; K263-R267 PolarHBondContact O-N 3.18Å; A264-R267 PolarHBondContact O-N 3.32Å; E265-R267 PolarHBondContact O-N 3.23Å; R267-L269 VanDerWaalsContact C-N 3.31Å; R267-L269 PolarHBondContact O-N 3.22Å; R267-E270 IonicContact CZ-OE2 2.78Å; R267-E270 IonicContact NH1-OE1 3.39Å; R267-E270 IonicContact NH1-OE2 2.76Å; R267-E270 PolarHBondContact NH1-OE2 3.36Å; R267-E270 PolarHBondContact O-N 2.77Å; R267-E271 PolarHBondContact O-N 3.25Å; R267-L295 HydrophobicContact CB-CD1 4.19Å
268L94.9Very high93.9Very high22 Ų2248.1 Ų48.112%0.11523%0.233CC..Hα-helixtrans-60.3-42.6175.4-70.8171.2000111.5A264 E265 E271 Q272 C291 E292 L295 I296 L325A264-L268 WeakPolarHBondContact O-CG 3.16Å; A264-L268 PolarHBondContact O-N 3.13Å; E265-L268 PolarHBondContact O-N 3.24Å; L268-E271 PolarHBondContact O-N 3.27Å; L268-Q272 WeakPolarHBondContact O-CB 3.22Å; L268-Q272 PolarHBondContact O-N 3.32Å; L268-C291 HydrophobicContact CD2-CB 3.61Å; L268-E292 HydrophobicContact CD2-CG 4.22Å; L268-L295 HydrophobicContact CD2-CD1 4.16Å; L268-L295 HydrophobicContact CG-CD1 4.27Å; L268-I296 HydrophobicContact CD1-CD1 4.1Å; L268-L325 HydrophobicContact CD1-CD2 4.07Å
269L94.6Very high93.8Very high77 Ų7748.1 Ų48.140%0.40323%0.232SC..Hα-helixtrans-67.5-37.5175.9-69.6172.6000112.6E265 A266 R267 R273E265-L269 WeakPolarHBondContact O-CG 3.34Å; E265-L269 PolarHBondContact O-N 3.39Å; E265-L269 VanDerWaalsContact O-N 3.15Å; A266-L269 PolarHBondContact O-N 3.18Å; R267-L269 VanDerWaalsContact C-N 3.31Å; R267-L269 PolarHBondContact O-N 3.22Å; L269-R273 WeakPolarHBondContact O-CG 3.33Å; L269-R273 PolarHBondContact O-N 2.81Å
270E93.9Very high93.7Very high50 Ų5046.5 Ų46.523%0.23422%0.224CC..Hα-helixtrans-62.7-48.1174.1-73.6174.2-164.600112A266 R267 Q272 R273 R274A266-E270 WeakPolarHBondContact O-CG 3.45Å; A266-E270 PolarHBondContact O-N 2.8Å; R267-E270 IonicContact CZ-OE2 2.78Å; R267-E270 IonicContact NH1-OE1 3.39Å; R267-E270 IonicContact NH1-OE2 2.76Å; R267-E270 PolarHBondContact NH1-OE2 3.36Å; R267-E270 PolarHBondContact O-N 2.77Å; E270-Q272 VanDerWaalsContact C-N 3.32Å; E270-Q272 PolarHBondContact O-N 2.95Å; E270-R273 VanDerWaalsContact CG-NH2 3.27Å; E270-R273 WeakPolarHBondContact O-CB 3.07Å; E270-R273 PolarHBondContact O-N 2.97Å; E270-R273 VanDerWaalsContact O-N 3.13Å; E270-R274 WeakPolarHBondContact O-CG 3.48Å; E270-R274 PolarHBondContact O-N 3.44Å; E270-R274 IonicContact OE2-CZ 2.77Å; E270-R274 IonicContact OE2-NH1 3.07Å; E270-R274 IonicContact OE2-NH2 2.76Å; E270-R274 PolarHBondContact OE2-NH2 2.96Å
271E94.4Very high93.5Very high5 Ų553.4 Ų53.42%0.02326%0.257CS..Hα-helixtrans-62.2-39.4177.5-69-59.2139.400111.9R191 Y244 R267 L268 R273 R274 V275 L287R191-E271 IonicContact CZ-OE1 3.71Å; R191-E271 IonicContact CZ-OE2 3.56Å; R191-E271 IonicContact NE-OE1 2.76Å; R191-E271 PolarHBondContact NE-OE1 3.42Å; R191-E271 IonicContact NE-OE2 2.75Å; R191-E271 VanDerWaalsContact NH2-CD 3.29Å; R191-E271 IonicContact NH2-OE1 3.41Å; R191-E271 PolarHBondContact NH2-OE1 3.5Å; R191-E271 VanDerWaalsContact NH2-OE1 3.11Å; R191-E271 IonicContact NH2-OE2 3.52Å; R191-E271 PolarHBondContact NH2-OE2 2.61Å; Y244-E271 HydrophobicContact CE2-CG 3.79Å; Y244-E271 WeakPolarHBondContact OH-CG 3.5Å; Y244-E271 PolarHBondContact OH-OE1 3.35Å; R267-E271 PolarHBondContact O-N 3.25Å; L268-E271 PolarHBondContact O-N 3.27Å; E271-R273 VanDerWaalsContact C-N 3.32Å; E271-R273 PolarHBondContact O-N 2.6Å; E271-R274 WeakPolarHBondContact O-CB 3.17Å; E271-R274 PolarHBondContact O-N 3Å; E271-R274 IonicContact OE1-CZ 3.39Å; E271-R274 IonicContact OE1-NE 3.22Å; E271-R274 IonicContact OE1-NH1 2.83Å; E271-R274 PolarHBondContact OE1-NH1 2.77Å; E271-V275 PolarHBondContact O-N 2.94Å; E271-V275 VanDerWaalsContact O-N 3.14Å; E271-L287 HydrophobicContact CB-CD2 4.07Å; E271-L287 HydrophobicContact CB-CG 4.46Å
272Q93.3Very high93.2Very high85 Ų8555 Ų5540%0.39727%0.268SS..Hα-helixtrans-59.9-43.2173.3-172.2-178.614.100111.7L268 E270 V275 Q276L268-Q272 WeakPolarHBondContact O-CB 3.22Å; L268-Q272 PolarHBondContact O-N 3.32Å; E270-Q272 VanDerWaalsContact C-N 3.32Å; E270-Q272 PolarHBondContact O-N 2.95Å; Q272-V275 PolarHBondContact O-N 3.18Å; Q272-Q276 WeakPolarHBondContact O-CG 3.48Å; Q272-Q276 PolarHBondContact O-N 3.01Å
273R93.3Very high93.1Very high129 Ų12951.1 Ų51.149%0.48725%0.251SS..Hα-helixtrans-65.1-39.4175.3-74.5-170.6-63-92.82.5112.2L269 E270 E271 V275 Q276 V277L269-R273 WeakPolarHBondContact O-CG 3.33Å; L269-R273 PolarHBondContact O-N 2.81Å; E270-R273 VanDerWaalsContact CG-NH2 3.27Å; E270-R273 WeakPolarHBondContact O-CB 3.07Å; E270-R273 PolarHBondContact O-N 2.97Å; E270-R273 VanDerWaalsContact O-N 3.13Å; E271-R273 VanDerWaalsContact C-N 3.32Å; E271-R273 PolarHBondContact O-N 2.6Å; R273-V275 VanDerWaalsContact C-N 3.26Å; R273-V275 PolarHBondContact O-N 3.34Å; R273-Q276 PolarHBondContact O-N 3.13Å; R273-Q276 VanDerWaalsContact O-N 3.1Å; R273-V277 VanDerWaalsContact O-CG2 3.29Å; R273-V277 WeakPolarHBondContact O-CG2 3.25Å; R273-V277 PolarHBondContact O-N 3.34Å
274R92.8Very high93Very high14 Ų1451.7 Ų51.75%0.05326%0.255CS..Hα-helixtrans-57.2-42.1177.1-72.6177.6179.910216.2111.4E190 E270 E271 Q276 V277 Y278E190-R274 IonicContact OE2-CZ 3.4Å; E190-R274 IonicContact OE2-NE 2.88Å; E190-R274 PolarHBondContact OE2-NE 2.68Å; E190-R274 IonicContact OE2-NH2 3.55Å; E270-R274 WeakPolarHBondContact O-CG 3.48Å; E270-R274 PolarHBondContact O-N 3.44Å; E270-R274 IonicContact OE2-CZ 2.77Å; E270-R274 IonicContact OE2-NH1 3.07Å; E270-R274 IonicContact OE2-NH2 2.76Å; E270-R274 PolarHBondContact OE2-NH2 2.96Å; E271-R274 WeakPolarHBondContact O-CB 3.17Å; E271-R274 PolarHBondContact O-N 3Å; E271-R274 IonicContact OE1-CZ 3.39Å; E271-R274 IonicContact OE1-NE 3.22Å; E271-R274 IonicContact OE1-NH1 2.83Å; E271-R274 PolarHBondContact OE1-NH1 2.77Å; R274-Q276 PolarHBondContact O-N 2.94Å; R274-V277 PolarHBondContact O-N 2.98Å; R274-Y278 HydrophobicContact CB-CE1 4.28Å; R274-Y278 HydrophobicContact CB-CE2 4.37Å; R274-Y278 WeakPolarHBondContact CD-OH 3.37Å; R274-Y278 HydrophobicContact CG-CE1 4.24Å; R274-Y278 VanDerWaalsContact CG-OH 3.23Å; R274-Y278 WeakPolarHBondContact CG-OH 3.31Å; R274-Y278 PolarHBondContact O-N 2.65Å; R274-Y278 VanDerWaalsContact O-N 3.14Å
275V93.1Very high92.8Very high7 Ų757 Ų574%0.04228%0.283CS..Hα-helixtrans-60.9-46.4175.8179.60000111.4E271 Q272 R273 V277 L279 Q284 L287E271-V275 PolarHBondContact O-N 2.94Å; E271-V275 VanDerWaalsContact O-N 3.14Å; Q272-V275 PolarHBondContact O-N 3.18Å; R273-V275 VanDerWaalsContact C-N 3.26Å; R273-V275 PolarHBondContact O-N 3.34Å; V275-V277 VanDerWaalsContact C-N 3.32Å; V275-V277 PolarHBondContact O-N 3.02Å; V275-L279 HydrophobicContact CG1-CB 4.41Å; V275-L279 HydrophobicContact CG2-CD1 3.9Å; V275-L279 PolarHBondContact O-N 3.23Å; V275-L279 VanDerWaalsContact O-O 3.11Å; V275-Q284 HydrophobicContact CG1-CB 3.97Å; V275-Q284 HydrophobicContact CG1-CG 4.49Å; V275-L287 HydrophobicContact CG2-CD2 3.54Å
276Q91.4Very high92.8Very high135 Ų13556.7 Ų56.763%0.63128%0.282SS*.Hα-helixtrans-65.8-30.8-179.5-67173.70.500113.8Q272 R273 R274Q272-Q276 WeakPolarHBondContact O-CG 3.48Å; Q272-Q276 PolarHBondContact O-N 3.01Å; R273-Q276 PolarHBondContact O-N 3.13Å; R273-Q276 VanDerWaalsContact O-N 3.1Å; R274-Q276 PolarHBondContact O-N 2.94Å
277V91.8Very high92.7Very high90 Ų9054.8 Ų54.855%0.54527%0.266SS..Hα-helixtrans-84.2-43.4-175.2177.40000112T198 R273 R274 V275T198-V277 HydrophobicContact CG2-CG1 4.3Å; R273-V277 VanDerWaalsContact O-CG2 3.29Å; R273-V277 WeakPolarHBondContact O-CG2 3.25Å; R273-V277 PolarHBondContact O-N 3.34Å; R274-V277 PolarHBondContact O-N 2.98Å; V275-V277 VanDerWaalsContact C-N 3.32Å; V275-V277 PolarHBondContact O-N 3.02Å
278Y89.7Confident92.7Very high6 Ų655.2 Ų55.22%0.02428%0.275CS..Hα-helixtrans-148.3-1.6-169.259.6-109.7000117.1I187 E190 T198 I201 R274I187-Y278 HydrophobicContact CD1-CE2 4.18Å; I187-Y278 HydrophobicContact CG1-CE2 4.23Å; E190-Y278 PolarHBondContact OE2-OH 3.25Å; E190-Y278 VanDerWaalsContact OE2-OH 3.08Å; T198-Y278 HydrophobicContact CG2-CD1 3.97Å; T198-Y278 HydrophobicContact CG2-CE1 4.24Å; I201-Y278 HydrophobicContact CB-CD2 4.14Å; I201-Y278 HydrophobicContact CB-CG 4.29Å; I201-Y278 HydrophobicContact CD1-CD2 4.49Å; I201-Y278 HydrophobicContact CD1-CE2 4.25Å; I201-Y278 HydrophobicContact CG2-CD2 3.37Å; I201-Y278 HydrophobicContact CG2-CE2 3.86Å; I201-Y278 HydrophobicContact CG2-CG 3.98Å; R274-Y278 HydrophobicContact CB-CE1 4.28Å; R274-Y278 HydrophobicContact CB-CE2 4.37Å; R274-Y278 WeakPolarHBondContact CD-OH 3.37Å; R274-Y278 HydrophobicContact CG-CE1 4.24Å; R274-Y278 VanDerWaalsContact CG-OH 3.23Å; R274-Y278 WeakPolarHBondContact CG-OH 3.31Å; R274-Y278 PolarHBondContact O-N 2.65Å; R274-Y278 VanDerWaalsContact O-N 3.14Å
279L92.1Very high92.6Very high17 Ų1761.3 Ų61.39%0.08930%0.296CS..SBendtrans-101.5169.7174.9-50.9172.6000111.4V205 F232 F236 V275V205-L279 HydrophobicContact CG2-CD2 4.37Å; F232-L279 HydrophobicContact CE1-CD2 3.69Å; F232-L279 HydrophobicContact CZ-CD2 3.73Å; F236-L279 HydrophobicContact CE1-CD1 3.78Å; F236-L279 HydrophobicContact CZ-CD1 3.72Å; V275-L279 HydrophobicContact CG1-CB 4.41Å; V275-L279 HydrophobicContact CG2-CD1 3.9Å; V275-L279 PolarHBondContact O-N 3.23Å; V275-L279 VanDerWaalsContact O-O 3.11Å
280H91.4Very high92.6Very high47 Ų4760.9 Ų60.922%0.21829%0.291CS..  trans-77.9142.9173.4-168.7-94.6000110.9V209 Y228 S282 T283V209-H280 HydrophobicContact CG2-CB 4.43Å; Y228-H280 HydrophobicContact CD1-CB 4.39Å; Y228-H280 HydrophobicContact CE1-CB 3.8Å; Y228-H280 HydrophobicContact CE2-CB 4.25Å; Y228-H280 PolarHBondContact OH-N 3.03Å; H280-S282 WeakPolarHBondContact ND1-CB 3.22Å; H280-S282 PolarHBondContact ND1-N 3.1Å; H280-S282 PolarHBondContact ND1-OG 3.5Å; H280-S282 PolarHBondContact O-N 3.27Å; H280-S282 VanDerWaalsContact O-N 3.13Å; H280-T283 WeakPolarHBondContact O-CB 3.46Å; H280-T283 PolarHBondContact O-N 2.62Å; H280-T283 PolarHBondContact O-OG1 3.09Å
281E91Very high92.7Very high150 Ų15058.6 Ų58.670%0.70128%0.28SS*.THydrogen-bonded Turntrans-57.7-29.6-177.462.1-178-176.600113.6T283 Q284E281-T283 PolarHBondContact O-N 2.82Å; E281-T283 VanDerWaalsContact O-N 3.13Å; E281-Q284 VanDerWaalsContact O-CB 3.26Å; E281-Q284 WeakPolarHBondContact O-CB 3.23Å; E281-Q284 PolarHBondContact O-N 3.28Å; E281-Q284 VanDerWaalsContact O-N 3.08Å
282S90Very high92.7Very high34 Ų3459.8 Ų59.824%0.23829%0.286CS..THydrogen-bonded Turntrans-60.7-23.5177.165.70000113.9H280 Q284H280-S282 WeakPolarHBondContact ND1-CB 3.22Å; H280-S282 PolarHBondContact ND1-N 3.1Å; H280-S282 PolarHBondContact ND1-OG 3.5Å; H280-S282 PolarHBondContact O-N 3.27Å; H280-S282 VanDerWaalsContact O-N 3.13Å; S282-Q284 VanDerWaalsContact C-N 3.3Å
283T92.4Very high92.7Very high0 Ų059 Ų590%028%0.282CS..Hα-helixtrans-78.3-17.5-179.5-54.60000112Y228 E233 F236 H280 E281 D285 E286 L287Y228-T283 VanDerWaalsContact CE1-OG1 3.26Å; Y228-T283 WeakPolarHBondContact CE1-OG1 3.34Å; Y228-T283 PolarHBondContact OH-OG1 2.81Å; E233-T283 HydrophobicContact CG-CG2 4.15Å; E233-T283 WeakPolarHBondContact OE1-CA 3.31Å; E233-T283 VanDerWaalsContact OE1-CB 3.26Å; E233-T283 WeakPolarHBondContact OE1-CB 3.42Å; E233-T283 PolarHBondContact OE1-N 3.43Å; E233-T283 PolarHBondContact OE1-OG1 3.5Å; F236-T283 HydrophobicContact CD1-CG2 4.16Å; F236-T283 HydrophobicContact CE1-CG2 3.96Å; H280-T283 WeakPolarHBondContact O-CB 3.46Å; H280-T283 PolarHBondContact O-N 2.62Å; H280-T283 PolarHBondContact O-OG1 3.09Å; E281-T283 PolarHBondContact O-N 2.82Å; E281-T283 VanDerWaalsContact O-N 3.13Å; T283-D285 PolarHBondContact O-N 2.67Å; T283-E286 PolarHBondContact O-N 2.91Å; T283-L287 HydrophobicContact CG2-CB 4.13Å; T283-L287 WeakPolarHBondContact O-CB 3.28Å; T283-L287 PolarHBondContact O-N 3.49Å
284Q92.6Very high92.7Very high72 Ų7252.8 Ų52.834%0.33626%0.259SS..Hα-helixtrans-55.2-52.7-173.6-169.6171.3-26.800112.3V275 E281 S282 A288V275-Q284 HydrophobicContact CG1-CB 3.97Å; V275-Q284 HydrophobicContact CG1-CG 4.49Å; E281-Q284 VanDerWaalsContact O-CB 3.26Å; E281-Q284 WeakPolarHBondContact O-CB 3.23Å; E281-Q284 PolarHBondContact O-N 3.28Å; E281-Q284 VanDerWaalsContact O-N 3.08Å; S282-Q284 VanDerWaalsContact C-N 3.3Å; Q284-A288 WeakPolarHBondContact O-CB 3.47Å; Q284-A288 PolarHBondContact O-N 3.09Å
285D92.4Very high92.8Very high114 Ų11452.3 Ų52.361%0.6126%0.257SS*.Hα-helixtrans-75.5-32.9-173.5-63.4-28.8000113T283 R289T283-D285 PolarHBondContact O-N 2.67Å; D285-R289 WeakPolarHBondContact O-CB 3.43Å; D285-R289 WeakPolarHBondContact O-CG 3.42Å; D285-R289 PolarHBondContact O-N 3.03Å; D285-R289 PolarHBondContact O-NE 3.03Å; D285-R289 VanDerWaalsContact O-NE 3.11Å
286E92.9Very high92.9Very high66 Ų6652 Ų5231%0.30826%0.255SS..Hα-helixtrans-72.6-42.1175.8-78.1-177.6-161.600111.5K229 L237 T283 R289 K290K229-E286 IonicContact NZ-OE1 2.88Å; L237-E286 HydrophobicContact CD1-CB 4.03Å; T283-E286 PolarHBondContact O-N 2.91Å; E286-R289 VanDerWaalsContact CG-NH2 3.25Å; E286-K290 WeakPolarHBondContact O-CB 3.49Å; E286-K290 WeakPolarHBondContact O-CG 3.4Å; E286-K290 PolarHBondContact O-N 3.36Å
287L94.5Very high93Very high3 Ų349.9 Ų49.92%0.01625%0.246CC..Hα-helixtrans-65.4-45.9175.6178.863.6000111.7F236 L237 T240 E271 V275 T283 R289 K290 C291F236-L287 HydrophobicContact CE1-CD1 3.72Å; F236-L287 HydrophobicContact CE1-CD2 3.93Å; F236-L287 HydrophobicContact CE1-CG 4.31Å; F236-L287 HydrophobicContact CZ-CD1 3.93Å; F236-L287 HydrophobicContact CZ-CD2 4.02Å; L237-L287 HydrophobicContact CD2-CB 3.92Å; L237-L287 HydrophobicContact CD2-CD1 3.96Å; T240-L287 HydrophobicContact CG2-CD1 3.77Å; E271-L287 HydrophobicContact CB-CD2 4.07Å; E271-L287 HydrophobicContact CB-CG 4.46Å; V275-L287 HydrophobicContact CG2-CD2 3.54Å; T283-L287 HydrophobicContact CG2-CB 4.13Å; T283-L287 WeakPolarHBondContact O-CB 3.28Å; T283-L287 PolarHBondContact O-N 3.49Å; L287-R289 PolarHBondContact O-N 3.27Å; L287-K290 PolarHBondContact O-N 2.93Å; L287-C291 WeakPolarHBondContact O-CB 3.28Å; L287-C291 PolarHBondContact O-N 2.93Å; L287-C291 PolarHBondContact O-SG 3.06Å
288A93.9Very high93Very high36 Ų3650.5 Ų50.530%0.29824%0.241SC..Hα-helixtrans-57.3-51.317800000110.8Q284 K290 C291 E292Q284-A288 WeakPolarHBondContact O-CB 3.47Å; Q284-A288 PolarHBondContact O-N 3.09Å; A288-K290 VanDerWaalsContact C-N 3.32Å; A288-K290 PolarHBondContact O-N 3.23Å; A288-C291 PolarHBondContact O-N 3.33Å; A288-C291 VanDerWaalsContact O-N 3.17Å; A288-E292 WeakPolarHBondContact O-CB 3.42Å; A288-E292 VanDerWaalsContact O-CG 3.25Å; A288-E292 WeakPolarHBondContact O-CG 3.2Å; A288-E292 PolarHBondContact O-N 3.29Å
289R93.9Very high93.2Very high151 Ų15151.2 Ų51.257%0.5725%0.245SC*.Hα-helixtrans-58-42176.9-79.5-177.2-70.6141.2-7.2112.8D285 E286 L287 E292 Q293D285-R289 WeakPolarHBondContact O-CB 3.43Å; D285-R289 WeakPolarHBondContact O-CG 3.42Å; D285-R289 PolarHBondContact O-N 3.03Å; D285-R289 PolarHBondContact O-NE 3.03Å; D285-R289 VanDerWaalsContact O-NE 3.11Å; E286-R289 VanDerWaalsContact CG-NH2 3.25Å; L287-R289 PolarHBondContact O-N 3.27Å; R289-E292 PolarHBondContact O-N 3.45Å; R289-Q293 VanDerWaalsContact O-CB 3.29Å; R289-Q293 WeakPolarHBondContact O-CB 3.47Å; R289-Q293 PolarHBondContact O-N 2.94Å
290K94.1Very high93.2Very high67 Ų6751.7 Ų51.729%0.29125%0.247SC..Hα-helixtrans-65.8-40.9177.5-80.6-68-173.1176.30112.5E241 E286 L287 A288 V294E241-K290 IonicContact OE2-NZ 3.73Å; E241-K290 PolarHBondContact OE2-NZ 3.13Å; E286-K290 WeakPolarHBondContact O-CB 3.49Å; E286-K290 WeakPolarHBondContact O-CG 3.4Å; E286-K290 PolarHBondContact O-N 3.36Å; L287-K290 PolarHBondContact O-N 2.93Å; A288-K290 VanDerWaalsContact C-N 3.32Å; A288-K290 PolarHBondContact O-N 3.23Å; K290-V294 WeakPolarHBondContact O-CB 3.45Å; K290-V294 VanDerWaalsContact O-CG2 3.23Å; K290-V294 WeakPolarHBondContact O-CG2 3.33Å; K290-V294 PolarHBondContact O-N 3.44Å; K290-V294 VanDerWaalsContact O-N 3.11Å
291C94.9Very high93.2Very high2 Ų257.3 Ų57.31%0.01427%0.273CS..Hα-helixtrans-67.6-43.2176.2-63.80000111.4L268 L287 A288 V294 L295L268-C291 HydrophobicContact CD2-CB 3.61Å; L287-C291 WeakPolarHBondContact O-CB 3.28Å; L287-C291 PolarHBondContact O-N 2.93Å; L287-C291 PolarHBondContact O-SG 3.06Å; A288-C291 PolarHBondContact O-N 3.33Å; A288-C291 VanDerWaalsContact O-N 3.17Å; C291-V294 PolarHBondContact O-N 3.11Å; C291-L295 HydrophobicContact CB-CD1 4.33Å; C291-L295 WeakPolarHBondContact O-CB 3.26Å; C291-L295 WeakPolarHBondContact O-CG 3.38Å; C291-L295 PolarHBondContact O-N 3.49Å
292E94.2Very high93.3Very high31 Ų3153.3 Ų53.315%0.14526%0.256CS..Hα-helixtrans-61.7-44.4176.9-72.8169.2169.200111.5L268 A288 R289 V294 I296 E297 R328 I329L268-E292 HydrophobicContact CD2-CG 4.22Å; A288-E292 WeakPolarHBondContact O-CB 3.42Å; A288-E292 VanDerWaalsContact O-CG 3.25Å; A288-E292 WeakPolarHBondContact O-CG 3.2Å; A288-E292 PolarHBondContact O-N 3.29Å; R289-E292 PolarHBondContact O-N 3.45Å; E292-V294 PolarHBondContact O-N 2.83Å; E292-I296 HydrophobicContact CG-CD1 4.39Å; E292-I296 WeakPolarHBondContact O-CA 3.19Å; E292-I296 VanDerWaalsContact O-CB 3.28Å; E292-I296 WeakPolarHBondContact O-CB 3.2Å; E292-I296 PolarHBondContact O-N 3.17Å; E292-E297 PolarHBondContact O-N 3.04Å; E292-R328 HydrophobicContact CG-CB 4.33Å; E292-R328 IonicContact OE1-NH1 3.44Å; E292-I329 HydrophobicContact CB-CD1 3.82Å
293Q93.4Very high93.5Very high67 Ų6751.7 Ų51.731%0.31325%0.245SC..Hα-helixtrans-58.1-47.1174.5174.1168.258.500112R289 E297 K298R289-Q293 VanDerWaalsContact O-CB 3.29Å; R289-Q293 WeakPolarHBondContact O-CB 3.47Å; R289-Q293 PolarHBondContact O-N 2.94Å; Q293-E297 WeakPolarHBondContact CG-OE2 3.24Å; Q293-E297 WeakPolarHBondContact O-CB 3.44Å; Q293-E297 PolarHBondContact O-N 3.3Å; Q293-K298 WeakPolarHBondContact O-CG 3.13Å; Q293-K298 PolarHBondContact O-N 2.84Å
294V94.6Very high93.5Very high0 Ų053.6 Ų53.60%025%0.254CS..Hα-helixtrans-79.3-40.4-172.8174.10000112.7E241 Y244 T245 K290 C291 E292 H299E241-V294 HydrophobicContact CB-CG2 4.11Å; E241-V294 HydrophobicContact CG-CG2 3.68Å; Y244-V294 VanDerWaalsContact C-CG1 3.49Å; T245-V294 VanDerWaalsContact N-CG1 3.26Å; T245-V294 VanDerWaalsContact OG1-CG1 3.28Å; T245-V294 WeakPolarHBondContact OG1-CG1 3.48Å; K290-V294 WeakPolarHBondContact O-CB 3.45Å; K290-V294 VanDerWaalsContact O-CG2 3.23Å; K290-V294 WeakPolarHBondContact O-CG2 3.33Å; K290-V294 PolarHBondContact O-N 3.44Å; K290-V294 VanDerWaalsContact O-N 3.11Å; C291-V294 PolarHBondContact O-N 3.11Å; E292-V294 PolarHBondContact O-N 2.83Å; V294-H299 PolarHBondContact O-CD2 3.34Å
295L94.6Very high93.5Very high3 Ų354.6 Ų54.62%0.01627%0.265CS..Hα-helixtrans-85.3-27.9-175.6-65.4172.7000112.6Y244 Y260 R267 L268 C291Y244-L295 HydrophobicContact CD1-CD1 4.4Å; Y244-L295 HydrophobicContact CD1-CD2 3.87Å; Y244-L295 HydrophobicContact CG-CD1 4.46Å; Y244-L295 HydrophobicContact CG-CD2 4.06Å; Y244-L295 HydrophobicContact CG-CG 4.37Å; Y260-L295 WeakPolarHBondContact CE1-O 3.25Å; Y260-L295 WeakPolarHBondContact OH-CA 3.4Å; Y260-L295 PolarHBondContact OH-O 2.88Å; R267-L295 HydrophobicContact CB-CD1 4.19Å; L268-L295 HydrophobicContact CD2-CD1 4.16Å; L268-L295 HydrophobicContact CG-CD1 4.27Å; C291-L295 HydrophobicContact CB-CD1 4.33Å; C291-L295 WeakPolarHBondContact O-CB 3.26Å; C291-L295 WeakPolarHBondContact O-CG 3.38Å; C291-L295 PolarHBondContact O-N 3.49Å
296I94.4Very high93.6Very high0 Ų051 Ų510%024%0.244CC..THydrogen-bonded Turntrans-118-61.3-173.7-53.4162000110.3L268 E292 K298 H299 L300 F303 L325 V326 I329L268-I296 HydrophobicContact CD1-CD1 4.1Å; E292-I296 HydrophobicContact CG-CD1 4.39Å; E292-I296 WeakPolarHBondContact O-CA 3.19Å; E292-I296 VanDerWaalsContact O-CB 3.28Å; E292-I296 WeakPolarHBondContact O-CB 3.2Å; E292-I296 PolarHBondContact O-N 3.17Å; I296-K298 PolarHBondContact O-N 2.8Å; I296-H299 CarbonylContact O-C 3.59Å; I296-H299 PolarHBondContact O-N 3.32Å; I296-L300 HydrophobicContact CG2-CD2 4.19Å; I296-L300 PolarHBondContact O-N 3.25Å; I296-F303 HydrophobicContact CG2-CE2 4.1Å; I296-L325 HydrophobicContact CD1-CB 4.19Å; I296-L325 HydrophobicContact CD1-CD2 4.2Å; I296-L325 HydrophobicContact CG1-CB 4.49Å; I296-V326 HydrophobicContact CG2-CG2 4.33Å; I296-I329 HydrophobicContact CB-CD1 4.2Å; I296-I329 HydrophobicContact CB-CG1 4.15Å; I296-I329 HydrophobicContact CG2-CD1 4.33Å; I296-I329 HydrophobicContact CG2-CG1 3.73Å
297E93.2Very high93.7Very high92 Ų9247.9 Ų47.943%0.4323%0.23SC..G310 helixtrans-58.6-46-170.3-164.6-176.5179.700112.8E292 Q293 H299 L300 I329E292-E297 PolarHBondContact O-N 3.04Å; Q293-E297 WeakPolarHBondContact CG-OE2 3.24Å; Q293-E297 WeakPolarHBondContact O-CB 3.44Å; Q293-E297 PolarHBondContact O-N 3.3Å; E297-H299 PolarHBondContact O-N 3.01Å; E297-H299 VanDerWaalsContact O-N 3.14Å; E297-L300 HydrophobicContact CG-CD1 4.22Å; E297-L300 WeakPolarHBondContact O-CG 2.83Å; E297-L300 PolarHBondContact O-N 3.06Å; E297-I329 HydrophobicContact CB-CD1 4.23Å; E297-I329 HydrophobicContact CG-CG2 4.26Å
298K92.9Very high93.7Very high103 Ų10350.1 Ų50.145%0.44824%0.24SC..G310 helixtrans-62.7-19.4178.1-72.4-176.2-171.2176.60114E241 Q293 I296E241-K298 IonicContact OE1-NZ 3.02Å; E241-K298 PolarHBondContact OE1-NZ 3.4Å; Q293-K298 WeakPolarHBondContact O-CG 3.13Å; Q293-K298 PolarHBondContact O-N 2.84Å; I296-K298 PolarHBondContact O-N 2.8Å
299H93.2Very high93.7Very high21 Ų2152.2 Ų52.210%0.09725%0.246CC..G310 helixtrans-115.413.2-174.9-58.4-63000113.1S248 L252 Y260 V294 I296 E297 E301 I302 F303S248-H299 WeakPolarHBondContact CB-NE2 3.13Å; S248-H299 PolarHBondContact OG-NE2 3.33Å; L252-H299 HydrophobicContact CD1-CB 4.22Å; Y260-H299 PolarHBondContact OH-CD2 3.16Å; V294-H299 PolarHBondContact O-CD2 3.34Å; I296-H299 CarbonylContact O-C 3.59Å; I296-H299 PolarHBondContact O-N 3.32Å; E297-H299 PolarHBondContact O-N 3.01Å; E297-H299 VanDerWaalsContact O-N 3.14Å; H299-E301 VanDerWaalsContact C-N 3.29Å; H299-E301 PolarHBondContact O-N 3.31Å; H299-I302 HydrophobicContact CB-CD1 4.5Å; H299-I302 WeakPolarHBondContact O-CB 3.43Å; H299-I302 PolarHBondContact O-N 2.92Å; H299-I302 VanDerWaalsContact O-N 3.11Å; H299-F303 HydrophobicContact CB-CE1 4.31Å; H299-F303 WeakPolarHBondContact O-CD1 3.41Å; H299-F303 PolarHBondContact O-N 3.11Å
300L92.1Very high93.8Very high27 Ų2745.1 Ų45.114%0.14122%0.22CC..Hα-helixtrans-57.6-36.6-176.4-80172.7000113.6I296 E297 I302 F303 H304 V326 I329I296-L300 HydrophobicContact CG2-CD2 4.19Å; I296-L300 PolarHBondContact O-N 3.25Å; E297-L300 HydrophobicContact CG-CD1 4.22Å; E297-L300 WeakPolarHBondContact O-CG 2.83Å; E297-L300 PolarHBondContact O-N 3.06Å; L300-I302 VanDerWaalsContact C-N 3.3Å; L300-I302 PolarHBondContact O-N 2.88Å; L300-F303 CarbonylContact O-C 3.55Å; L300-F303 WeakPolarHBondContact O-CB 3.28Å; L300-F303 PolarHBondContact O-N 3.46Å; L300-F303 VanDerWaalsContact O-N 3.11Å; L300-H304 PolarHBondContact O-CD2 3.5Å; L300-H304 VanDerWaalsContact O-CD2 3.24Å; L300-H304 PolarHBondContact O-N 3.34Å; L300-V326 HydrophobicContact CD2-CG1 3.97Å; L300-V326 HydrophobicContact CD2-CG2 4.01Å; L300-I329 HydrophobicContact CD1-CG2 4.46Å
301E91.6Very high93.8Very high164 Ų16442 Ų4277%0.76621%0.206SC*.Hα-helixtrans-63-37.4178.5-64.2-171.7165.300112.7H299 F303 H304 T305H299-E301 VanDerWaalsContact C-N 3.29Å; H299-E301 PolarHBondContact O-N 3.31Å; E301-F303 VanDerWaalsContact C-N 3.32Å; E301-H304 PolarHBondContact O-N 3.23Å; E301-T305 PolarHBondContact O-N 3.11Å; E301-T305 VanDerWaalsContact O-N 3.1Å; E301-T305 PolarHBondContact O-OG1 3.01Å
302I93.4Very high93.7Very high67 Ų6746.1 Ų46.134%0.34423%0.228SC..Hα-helixtrans-66.5-40.6175.1-59.2172.8000109.2L252 V257 H299 L300 T305 E306L252-I302 HydrophobicContact CD1-CD1 4.13Å; V257-I302 HydrophobicContact CG1-CG2 4.39Å; V257-I302 HydrophobicContact CG2-CG2 3.45Å; V257-I302 VanDerWaalsContact CG2-CG2 3.45Å; H299-I302 HydrophobicContact CB-CD1 4.5Å; H299-I302 WeakPolarHBondContact O-CB 3.43Å; H299-I302 PolarHBondContact O-N 2.92Å; H299-I302 VanDerWaalsContact O-N 3.11Å; L300-I302 VanDerWaalsContact C-N 3.3Å; L300-I302 PolarHBondContact O-N 2.88Å; I302-T305 PolarHBondContact O-N 3.23Å; I302-E306 WeakPolarHBondContact O-CB 3.48Å; I302-E306 PolarHBondContact O-N 3.35Å
303F93.8Very high93.6Very high0 Ų047.4 Ų47.40%024%0.244CC..Hα-helixtrans-65.2-41.5177.6-75.427.7000110.9V257 Y260 M261 I296 H299 L300 E301 T305 E306 F307 M322 L325 V326V257-F303 HydrophobicContact CG1-CD1 4.07Å; V257-F303 HydrophobicContact CG1-CE1 4.22Å; Y260-F303 AromaticContact CD1-CE1 3.76Å; Y260-F303 HydrophobicContact CD1-CE1 3.76Å; Y260-F303 AromaticContact CD1-CZ 3.98Å; Y260-F303 HydrophobicContact CD1-CZ 3.98Å; Y260-F303 AromaticContact CE1-CE1 3.68Å; Y260-F303 HydrophobicContact CE1-CE1 3.68Å; Y260-F303 AromaticContact CE1-CZ 3.73Å; Y260-F303 HydrophobicContact CE1-CZ 3.73Å; M261-F303 HydrophobicContact CG-CE2 4.35Å; M261-F303 HydrophobicContact CG-CZ 4.12Å; I296-F303 HydrophobicContact CG2-CE2 4.1Å; H299-F303 HydrophobicContact CB-CE1 4.31Å; H299-F303 WeakPolarHBondContact O-CD1 3.41Å; H299-F303 PolarHBondContact O-N 3.11Å; L300-F303 CarbonylContact O-C 3.55Å; L300-F303 WeakPolarHBondContact O-CB 3.28Å; L300-F303 PolarHBondContact O-N 3.46Å; L300-F303 VanDerWaalsContact O-N 3.11Å; E301-F303 VanDerWaalsContact C-N 3.32Å; F303-T305 VanDerWaalsContact C-N 3.34Å; F303-T305 PolarHBondContact O-N 3.03Å; F303-E306 PolarHBondContact O-N 3.36Å; F303-F307 VanDerWaalsContact O-CB 3.27Å; F303-F307 WeakPolarHBondContact O-CB 3.47Å; F303-F307 PolarHBondContact O-N 3.4Å; F303-M322 HydrophobicContact CB-CE 4.31Å; F303-M322 HydrophobicContact CB-SD 4.15Å; F303-M322 HydrophobicContact CD2-CG 4.17Å; F303-M322 WeakPolarHBondContact O-CE 3.32Å; F303-M322 VanDerWaalsContact O-SD 3.4Å; F303-L325 HydrophobicContact CE2-CD1 4.38Å; F303-V326 HydrophobicContact CD2-CG2 3.76Å; F303-V326 HydrophobicContact CE2-CG2 4.41Å
304H93.1Very high93.5Very high40 Ų4048 Ų4819%0.18525%0.25CC..Hα-helixtrans-60.2-43.9176-62.9165.1000112L300 E301 F307 Q308 L339L300-H304 PolarHBondContact O-CD2 3.5Å; L300-H304 VanDerWaalsContact O-CD2 3.24Å; L300-H304 PolarHBondContact O-N 3.34Å; E301-H304 PolarHBondContact O-N 3.23Å; H304-F307 WeakPolarHBondContact O-CB 3.44Å; H304-F307 PolarHBondContact O-N 3.18Å; H304-Q308 PolarHBondContact O-N 2.97Å; H304-L339 HydrophobicContact CB-CD1 4.06Å; H304-L339 VanDerWaalsContact O-CD1 3.32Å; H304-L339 WeakPolarHBondContact O-CD1 3.32Å
305T92.8Very high93.5Very high93 Ų9352.8 Ų52.857%0.57127%0.27SS*.Hα-helixtrans-65.3-46.4178.6-54.40000110.8E301 I302 F303 F307 Q308 N309E301-T305 PolarHBondContact O-N 3.11Å; E301-T305 VanDerWaalsContact O-N 3.1Å; E301-T305 PolarHBondContact O-OG1 3.01Å; I302-T305 PolarHBondContact O-N 3.23Å; F303-T305 VanDerWaalsContact C-N 3.34Å; F303-T305 PolarHBondContact O-N 3.03Å; T305-F307 VanDerWaalsContact C-N 3.33Å; T305-F307 PolarHBondContact O-N 3.27Å; T305-Q308 PolarHBondContact O-N 3.36Å; T305-N309 PolarHBondContact O-N 2.97Å
306E94.5Very high93.4Very high38 Ų3855.9 Ų55.918%0.17829%0.287CS..Hα-helixtrans-68.1-33.3178.8-172.667.9177.600112.3V257 I302 F303 Q308 N309 L310 M322V257-E306 HydrophobicContact CB-CB 4.09Å; V257-E306 HydrophobicContact CB-CG 3.79Å; V257-E306 HydrophobicContact CG1-CB 3.95Å; V257-E306 HydrophobicContact CG1-CG 3.94Å; V257-E306 HydrophobicContact CG2-CB 4.27Å; V257-E306 HydrophobicContact CG2-CG 4.36Å; I302-E306 WeakPolarHBondContact O-CB 3.48Å; I302-E306 PolarHBondContact O-N 3.35Å; F303-E306 PolarHBondContact O-N 3.36Å; E306-Q308 PolarHBondContact O-N 3.37Å; E306-N309 WeakPolarHBondContact O-CB 3.47Å; E306-N309 PolarHBondContact O-N 3.37Å; E306-N309 PolarHBondContact OE2-ND2 2.96Å; E306-L310 HydrophobicContact CG-CD1 4.11Å; E306-L310 HydrophobicContact CG-CG 4.06Å; E306-L310 VanDerWaalsContact O-CG 3.31Å; E306-L310 WeakPolarHBondContact O-CG 3.27Å; E306-L310 PolarHBondContact O-N 3.36Å; E306-M322 HydrophobicContact CB-CE 4.19Å; E306-M322 HydrophobicContact CG-CE 4.33Å
307F95.4Very high93.3Very high0 Ų063.7 Ų63.70%032%0.323CS..Hα-helixtrans-55.4-42.4176.2-172.4-107.8000111.5F303 H304 T305 L310 L311 L319 M322 L336 L339 L340 F385 F391F303-F307 VanDerWaalsContact O-CB 3.27Å; F303-F307 WeakPolarHBondContact O-CB 3.47Å; F303-F307 PolarHBondContact O-N 3.4Å; H304-F307 WeakPolarHBondContact O-CB 3.44Å; H304-F307 PolarHBondContact O-N 3.18Å; T305-F307 VanDerWaalsContact C-N 3.33Å; T305-F307 PolarHBondContact O-N 3.27Å; F307-L310 PolarHBondContact O-N 3.46Å; F307-L311 HydrophobicContact CD1-CD1 3.7Å; F307-L311 HydrophobicContact CD1-CG 4.28Å; F307-L311 HydrophobicContact CE1-CD1 3.49Å; F307-L311 VanDerWaalsContact CE1-CD1 3.49Å; F307-L311 HydrophobicContact CE1-CG 4.13Å; F307-L311 HydrophobicContact CZ-CD1 4.21Å; F307-L311 HydrophobicContact CZ-CD2 4.47Å; F307-L311 HydrophobicContact CZ-CG 4.44Å; F307-L311 VanDerWaalsContact O-CG 3.3Å; F307-L311 WeakPolarHBondContact O-CG 3.49Å; F307-L311 PolarHBondContact O-N 3.1Å; F307-L319 HydrophobicContact CD2-CD2 3.43Å; F307-L319 VanDerWaalsContact CD2-CD2 3.43Å; F307-L319 HydrophobicContact CE2-CD2 3.41Å; F307-L319 VanDerWaalsContact CE2-CD2 3.41Å; F307-L319 HydrophobicContact CG-CD2 4.25Å; F307-L319 HydrophobicContact CZ-CD2 4.2Å; F307-M322 HydrophobicContact CB-CE 4.39Å; F307-M322 HydrophobicContact CB-SD 3.63Å; F307-M322 HydrophobicContact CD2-SD 3.55Å; F307-M322 VanDerWaalsContact CD2-SD 3.55Å; F307-M322 HydrophobicContact CG-SD 4.04Å; F307-L336 HydrophobicContact CB-CD2 3.86Å; F307-L336 HydrophobicContact CD1-CD2 3.88Å; F307-L336 HydrophobicContact CD2-CD2 3.91Å; F307-L336 HydrophobicContact CE1-CB 4.23Å; F307-L336 HydrophobicContact CE1-CD2 4.35Å; F307-L336 WeakPolarHBondContact CE1-O 3.04Å; F307-L336 HydrophobicContact CE2-CD1 4.47Å; F307-L336 HydrophobicContact CE2-CD2 4.38Å; F307-L336 HydrophobicContact CG-CD2 3.63Å; F307-L336 HydrophobicContact CZ-CB 4.24Å; F307-L339 HydrophobicContact CB-CD1 4.41Å; F307-L339 HydrophobicContact CD1-CB 3.84Å; F307-L339 HydrophobicContact CD1-CD1 3.96Å; F307-L339 HydrophobicContact CE1-CB 4.06Å; F307-L340 HydrophobicContact CE1-CB 4.32Å; F307-F385 HydrophobicContact CE2-CE1 4.16Å; F307-F385 AromaticContact CE2-CZ 3.98Å; F307-F385 HydrophobicContact CE2-CZ 3.98Å; F307-F385 HydrophobicContact CZ-CE1 4.43Å; F307-F385 AromaticContact CZ-CZ 3.89Å; F307-F385 HydrophobicContact CZ-CZ 3.89Å; F307-F391 HydrophobicContact CZ-CE1 4.29Å
308Q94.2Very high93.4Very high50 Ų5060.4 Ų60.423%0.23431%0.309CS..Hα-helixtrans-62.6-45.3175.5-174.258.458.300111.5H304 T305 E306 L310 L311 D312 H343H304-Q308 PolarHBondContact O-N 2.97Å; T305-Q308 PolarHBondContact O-N 3.36Å; E306-Q308 PolarHBondContact O-N 3.37Å; Q308-L310 VanDerWaalsContact C-N 3.32Å; Q308-L310 PolarHBondContact O-N 3.04Å; Q308-L311 WeakPolarHBondContact O-CB 3.3Å; Q308-L311 PolarHBondContact O-N 3.46Å; Q308-D312 PolarHBondContact NE2-OD1 3.36Å; Q308-D312 VanDerWaalsContact NE2-OD1 3.12Å; Q308-D312 PolarHBondContact NE2-OD2 2.83Å; Q308-D312 VanDerWaalsContact NE2-OD2 3.15Å; Q308-D312 VanDerWaalsContact O-CG 3.29Å; Q308-D312 PolarHBondContact O-N 3.27Å; Q308-H343 PolarHBondContact NE2-ND1 3.41Å
309N94.3Very high93.5Very high80 Ų8055.5 Ų55.543%0.42829%0.287SS..Hα-helixtrans-60.9-40.9176.9-61.6-28.7000112.1T305 E306 D312 A313T305-N309 PolarHBondContact O-N 2.97Å; E306-N309 WeakPolarHBondContact O-CB 3.47Å; E306-N309 PolarHBondContact O-N 3.37Å; E306-N309 PolarHBondContact OE2-ND2 2.96Å; N309-D312 PolarHBondContact O-N 2.95Å; N309-A313 VanDerWaalsContact O-CB 3.31Å; N309-A313 WeakPolarHBondContact O-CB 3.41Å; N309-A313 PolarHBondContact O-N 3.47Å
310L94.9Very high93.6Very high2 Ų255 Ų551%0.0129%0.287CS..Hα-helixtrans-68.6-36.4178.9-66175.9000112.2T258 M261 E306 F307 Q308 A313 D314 K315 D318 L319 M322T258-L310 HydrophobicContact CG2-CD1 4.49Å; T258-L310 HydrophobicContact CG2-CD2 3.73Å; M261-L310 HydrophobicContact CE-CD1 4.09Å; E306-L310 HydrophobicContact CG-CD1 4.11Å; E306-L310 HydrophobicContact CG-CG 4.06Å; E306-L310 VanDerWaalsContact O-CG 3.31Å; E306-L310 WeakPolarHBondContact O-CG 3.27Å; E306-L310 PolarHBondContact O-N 3.36Å; F307-L310 PolarHBondContact O-N 3.46Å; Q308-L310 VanDerWaalsContact C-N 3.32Å; Q308-L310 PolarHBondContact O-N 3.04Å; L310-A313 PolarHBondContact O-N 2.7Å; L310-D314 PolarHBondContact O-N 3.48Å; L310-D314 VanDerWaalsContact O-N 3.1Å; L310-K315 HydrophobicContact CD2-CB 3.93Å; L310-K315 HydrophobicContact CD2-CD 3.76Å; L310-K315 HydrophobicContact CD2-CG 4.39Å; L310-K315 PolarHBondContact O-N 3.36Å; L310-D318 HydrophobicContact CD1-CB 3.95Å; L310-D318 HydrophobicContact CD2-CB 4.01Å; L310-L319 HydrophobicContact CB-CD2 3.63Å; L310-L319 HydrophobicContact CB-CG 3.94Å; L310-L319 HydrophobicContact CD1-CD2 4.38Å; L310-M322 HydrophobicContact CD1-CE 3.79Å
311L94.2Very high93.7Very high3 Ų355.7 Ų55.72%0.01629%0.288CS..Hα-helixtrans-63.6-46171.7-74.1173.3000111.1F307 Q308 A313 D314 L319 L340 H343 L380F307-L311 HydrophobicContact CD1-CD1 3.7Å; F307-L311 HydrophobicContact CD1-CG 4.28Å; F307-L311 HydrophobicContact CE1-CD1 3.49Å; F307-L311 VanDerWaalsContact CE1-CD1 3.49Å; F307-L311 HydrophobicContact CE1-CG 4.13Å; F307-L311 HydrophobicContact CZ-CD1 4.21Å; F307-L311 HydrophobicContact CZ-CD2 4.47Å; F307-L311 HydrophobicContact CZ-CG 4.44Å; F307-L311 VanDerWaalsContact O-CG 3.3Å; F307-L311 WeakPolarHBondContact O-CG 3.49Å; F307-L311 PolarHBondContact O-N 3.1Å; Q308-L311 WeakPolarHBondContact O-CB 3.3Å; Q308-L311 PolarHBondContact O-N 3.46Å; L311-A313 VanDerWaalsContact C-N 3.26Å; L311-A313 PolarHBondContact O-N 3.37Å; L311-D314 PolarHBondContact O-N 2.96Å; L311-L319 HydrophobicContact CD2-CD1 3.79Å; L311-L319 HydrophobicContact CD2-CD2 4.11Å; L311-L319 HydrophobicContact CG-CD1 4.43Å; L311-L319 HydrophobicContact CG-CD2 4.08Å; L311-L340 HydrophobicContact CD1-CD1 4.29Å; L311-L340 HydrophobicContact CD2-CD1 3.63Å; L311-H343 HydrophobicContact CD1-CB 3.93Å; L311-L380 HydrophobicContact CD2-CD2 3.99Å
312D92.4Very high93.9Very high88 Ų8847.9 Ų47.947%0.47125%0.252SS..Hα-helixtrans-67.5-27.3179.9-65-30.5000112.6Q308 N309 H343Q308-D312 PolarHBondContact NE2-OD1 3.36Å; Q308-D312 VanDerWaalsContact NE2-OD1 3.12Å; Q308-D312 PolarHBondContact NE2-OD2 2.83Å; Q308-D312 VanDerWaalsContact NE2-OD2 3.15Å; Q308-D312 VanDerWaalsContact O-CG 3.29Å; Q308-D312 PolarHBondContact O-N 3.27Å; N309-D312 PolarHBondContact O-N 2.95Å; D312-H343 IonicContact OD1-CE1 2.85Å; D312-H343 PolarHBondContact OD1-CE1 3.11Å; D312-H343 IonicContact OD1-ND1 3Å; D312-H343 PolarHBondContact OD1-ND1 3.39Å
313A93.3Very high94Very high58 Ų5845.8 Ų45.848%0.47924%0.239SC..THydrogen-bonded Turntrans-94.23.8176.900000114.8N309 L310 L311 K315N309-A313 VanDerWaalsContact O-CB 3.31Å; N309-A313 WeakPolarHBondContact O-CB 3.41Å; N309-A313 PolarHBondContact O-N 3.47Å; L310-A313 PolarHBondContact O-N 2.7Å; L311-A313 VanDerWaalsContact C-N 3.26Å; L311-A313 PolarHBondContact O-N 3.37Å; A313-K315 VanDerWaalsContact C-N 3.27Å; A313-K315 HydrophobicContact CB-CG 4.17Å; A313-K315 PolarHBondContact O-N 2.85Å
314D91.3Very high94Very high80 Ų8048.7 Ų48.743%0.42826%0.255SS..THydrogen-bonded Turntrans54.434.4-179.2-71-41.6000114.6L310 L311 N316 K376L310-D314 PolarHBondContact O-N 3.48Å; L310-D314 VanDerWaalsContact O-N 3.1Å; L311-D314 PolarHBondContact O-N 2.96Å; D314-N316 PolarHBondContact O-N 3.45Å; D314-N316 VanDerWaalsContact O-N 3.09Å; D314-N316 PolarHBondContact O-OD1 3.27Å; D314-K376 WeakPolarHBondContact OD1-CE 3.46Å; D314-K376 IonicContact OD1-NZ 2.81Å; D314-K376 PolarHBondContact OD1-NZ 3Å; D314-K376 IonicContact OD2-NZ 3.11Å; D314-K376 PolarHBondContact OD2-NZ 3.38Å
315K93.4Very high94.1Very high99 Ų9947 Ų4743%0.4325%0.247SC..  trans-8671.9-179-69.9-169.7179.6179.80112.9L310 A313 E317 D318 L319L310-K315 HydrophobicContact CD2-CB 3.93Å; L310-K315 HydrophobicContact CD2-CD 3.76Å; L310-K315 HydrophobicContact CD2-CG 4.39Å; L310-K315 PolarHBondContact O-N 3.36Å; A313-K315 VanDerWaalsContact C-N 3.27Å; A313-K315 HydrophobicContact CB-CG 4.17Å; A313-K315 PolarHBondContact O-N 2.85Å; K315-E317 PolarHBondContact O-N 2.78Å; K315-D318 HydrophobicContact CB-CB 4.35Å; K315-D318 PolarHBondContact O-N 2.84Å; K315-L319 WeakPolarHBondContact O-CG 3.46Å; K315-L319 PolarHBondContact O-N 3.24Å; K315-L319 VanDerWaalsContact O-N 3.09Å
316N92.5Very high94.2Very high69 Ų6942.6 Ų42.637%0.36922%0.22SC..Hα-helixtrans-59.6-35.2-172.2-61.6-12.2000115.1D314 L319 G320 L380D314-N316 PolarHBondContact O-N 3.45Å; D314-N316 VanDerWaalsContact O-N 3.09Å; D314-N316 PolarHBondContact O-OD1 3.27Å; N316-L319 PolarHBondContact O-N 3.35Å; N316-G320 PolarHBondContact O-N 3.24Å; N316-L380 HydrophobicContact CB-CD1 4.07Å; N316-L380 WeakPolarHBondContact OD1-CD1 3.32Å
317E93.1Very high94.1Very high164 Ų16443.3 Ų43.377%0.76623%0.23SC*.Hα-helixtrans-67.3-42.7178.5-66.1-174.8177.500112.1K315 G320 R321K315-E317 PolarHBondContact O-N 2.78Å; E317-G320 PolarHBondContact O-N 3.14Å; E317-R321 PolarHBondContact O-N 3.44Å
318D94.1Very high93.9Very high23 Ų2349.3 Ų49.312%0.12325%0.252CS..Hα-helixtrans-69.3-35.8178.1-66.4-37.2000111.2T258 M261 L310 K315 G320 R321 M322T258-D318 HydrophobicContact CG2-CB 4.21Å; M261-D318 HydrophobicContact CE-CB 4.4Å; L310-D318 HydrophobicContact CD1-CB 3.95Å; L310-D318 HydrophobicContact CD2-CB 4.01Å; K315-D318 HydrophobicContact CB-CB 4.35Å; K315-D318 PolarHBondContact O-N 2.84Å; D318-G320 VanDerWaalsContact C-N 3.33Å; D318-R321 PolarHBondContact O-N 3.11Å; D318-R321 IonicContact OD1-CZ 3.82Å; D318-R321 IonicContact OD1-NH1 2.74Å; D318-R321 PolarHBondContact OD1-NH1 3.19Å; D318-M322 PolarHBondContact O-N 3.36Å
319L95.2Very high93.8Very high0 Ų047.9 Ų47.90%025%0.246CC..Hα-helixtrans-60.6-41.9171.3-70.6169.5000111.8F307 L310 L311 K315 N316 M322 Y323 L380 F385F307-L319 HydrophobicContact CD2-CD2 3.43Å; F307-L319 VanDerWaalsContact CD2-CD2 3.43Å; F307-L319 HydrophobicContact CE2-CD2 3.41Å; F307-L319 VanDerWaalsContact CE2-CD2 3.41Å; F307-L319 HydrophobicContact CG-CD2 4.25Å; F307-L319 HydrophobicContact CZ-CD2 4.2Å; L310-L319 HydrophobicContact CB-CD2 3.63Å; L310-L319 HydrophobicContact CB-CG 3.94Å; L310-L319 HydrophobicContact CD1-CD2 4.38Å; L311-L319 HydrophobicContact CD2-CD1 3.79Å; L311-L319 HydrophobicContact CD2-CD2 4.11Å; L311-L319 HydrophobicContact CG-CD1 4.43Å; L311-L319 HydrophobicContact CG-CD2 4.08Å; K315-L319 WeakPolarHBondContact O-CG 3.46Å; K315-L319 PolarHBondContact O-N 3.24Å; K315-L319 VanDerWaalsContact O-N 3.09Å; N316-L319 PolarHBondContact O-N 3.35Å; L319-M322 PolarHBondContact O-N 2.93Å; L319-Y323 WeakPolarHBondContact O-CB 3.43Å; L319-Y323 PolarHBondContact O-N 3.19Å; L319-L380 HydrophobicContact CD1-CD1 3.87Å; L319-L380 HydrophobicContact CD1-CD2 4.28Å; L319-F385 HydrophobicContact CB-CE1 4.07Å; L319-F385 HydrophobicContact CB-CZ 4.23Å
320G95.3Very high93.4Very high9 Ų950 Ų509%0.09326%0.262CS..Hα-helixtrans-66.1-39.3176.700000112.9N316 E317 D318 Y323 N324 A384N316-G320 PolarHBondContact O-N 3.24Å; E317-G320 PolarHBondContact O-N 3.14Å; D318-G320 VanDerWaalsContact C-N 3.33Å; G320-Y323 PolarHBondContact O-N 3.5Å; G320-N324 PolarHBondContact O-N 3Å; G320-N324 PolarHBondContact O-ND2 3.44Å; G320-A384 VanDerWaalsContact CA-O 3.26Å; G320-A384 WeakPolarHBondContact CA-O 3.35Å
321R95.1Very high92.8Very high43 Ų4357.1 Ų57.116%0.16230%0.3CS..Hα-helixtrans-63.1-44.4173.2-166.8179.1-5896.65.8111.6M261 E265 E317 D318 Y323 N324 L325M261-R321 HydrophobicContact CB-CG 4.36Å; E265-R321 IonicContact OE2-NE 3.13Å; E317-R321 PolarHBondContact O-N 3.44Å; D318-R321 PolarHBondContact O-N 3.11Å; D318-R321 IonicContact OD1-CZ 3.82Å; D318-R321 IonicContact OD1-NH1 2.74Å; D318-R321 PolarHBondContact OD1-NH1 3.19Å; R321-Y323 VanDerWaalsContact C-N 3.32Å; R321-Y323 PolarHBondContact O-N 3.34Å; R321-N324 PolarHBondContact O-N 2.99Å; R321-L325 HydrophobicContact CG-CD1 4.38Å; R321-L325 WeakPolarHBondContact O-CG 3.39Å; R321-L325 PolarHBondContact O-N 3.31Å
322M95.4Very high92.5Very high0 Ų057.4 Ų57.40%030%0.304CS..Hα-helixtrans-60.5-44176.8-167.9176.5-72.200111.3M261 F303 E306 F307 L310 D318 L319 N324 L325 V326 L336M261-M322 HydrophobicContact CE-CB 4.4Å; M261-M322 HydrophobicContact CE-CE 3.88Å; M261-M322 HydrophobicContact SD-CB 3.55Å; M261-M322 VanDerWaalsContact SD-CB 3.55Å; M261-M322 HydrophobicContact SD-CE 3.62Å; M261-M322 HydrophobicContact SD-CG 3.85Å; F303-M322 HydrophobicContact CB-CE 4.31Å; F303-M322 HydrophobicContact CB-SD 4.15Å; F303-M322 HydrophobicContact CD2-CG 4.17Å; F303-M322 WeakPolarHBondContact O-CE 3.32Å; F303-M322 VanDerWaalsContact O-SD 3.4Å; E306-M322 HydrophobicContact CB-CE 4.19Å; E306-M322 HydrophobicContact CG-CE 4.33Å; F307-M322 HydrophobicContact CB-CE 4.39Å; F307-M322 HydrophobicContact CB-SD 3.63Å; F307-M322 HydrophobicContact CD2-SD 3.55Å; F307-M322 VanDerWaalsContact CD2-SD 3.55Å; F307-M322 HydrophobicContact CG-SD 4.04Å; L310-M322 HydrophobicContact CD1-CE 3.79Å; D318-M322 PolarHBondContact O-N 3.36Å; L319-M322 PolarHBondContact O-N 2.93Å; M322-N324 PolarHBondContact O-N 3.35Å; M322-L325 PolarHBondContact O-N 3.3Å; M322-V326 HydrophobicContact CG-CG2 4.23Å; M322-V326 WeakPolarHBondContact O-CG2 3.39Å; M322-V326 PolarHBondContact O-N 3.16Å; M322-L336 HydrophobicContact SD-CD2 4.41Å
323Y95.4Very high92.5Very high22 Ų2254.3 Ų54.39%0.08629%0.287CS..Hα-helixtrans-57.3-49.6175.1168.1-96.5000111.9L319 G320 R321 L325 V326 S327 L333 F385 N386 D388 F391L319-Y323 WeakPolarHBondContact O-CB 3.43Å; L319-Y323 PolarHBondContact O-N 3.19Å; G320-Y323 PolarHBondContact O-N 3.5Å; R321-Y323 VanDerWaalsContact C-N 3.32Å; R321-Y323 PolarHBondContact O-N 3.34Å; Y323-L325 VanDerWaalsContact C-N 3.27Å; Y323-L325 PolarHBondContact O-N 2.98Å; Y323-V326 PolarHBondContact O-N 3.47Å; Y323-S327 WeakPolarHBondContact O-CB 3.49Å; Y323-S327 PolarHBondContact O-N 2.96Å; Y323-S327 PolarHBondContact O-OG 3.4Å; Y323-L333 HydrophobicContact CD2-CD1 4.45Å; Y323-L333 HydrophobicContact CD2-CD2 3.96Å; Y323-L333 HydrophobicContact CE2-CD1 3.94Å; Y323-L333 HydrophobicContact CE2-CD2 4.29Å; Y323-F385 HydrophobicContact CD2-CB 4.16Å; Y323-F385 AromaticContact CD2-CD1 3.99Å; Y323-F385 HydrophobicContact CD2-CD1 3.99Å; Y323-F385 HydrophobicContact CD2-CG 4.42Å; Y323-F385 HydrophobicContact CE2-CB 4.3Å; Y323-F385 HydrophobicContact CG-CB 4.41Å; Y323-F385 AromaticContact CG-CD1 3.84Å; Y323-F385 HydrophobicContact CG-CD1 3.84Å; Y323-N386 HydrophobicContact CE1-CB 4.17Å; Y323-D388 HydrophobicContact CE2-CB 4.1Å; Y323-F391 HydrophobicContact CD2-CD2 4.24Å; Y323-F391 AromaticContact CD2-CE2 3.61Å; Y323-F391 HydrophobicContact CD2-CE2 3.61Å; Y323-F391 HydrophobicContact CD2-CZ 4.25Å; Y323-F391 HydrophobicContact CE2-CD2 4.06Å; Y323-F391 AromaticContact CE2-CE2 3.74Å; Y323-F391 HydrophobicContact CE2-CE2 3.74Å
324N94.4Very high92.4Very high62 Ų6253.5 Ų53.533%0.33229%0.285SS..Hα-helixtrans-64.4-28.5-179.5-70.5-27.8000113.8G320 R321 M322 S327 R328G320-N324 PolarHBondContact O-N 3Å; G320-N324 PolarHBondContact O-ND2 3.44Å; R321-N324 PolarHBondContact O-N 2.99Å; M322-N324 PolarHBondContact O-N 3.35Å; N324-S327 PolarHBondContact O-OG 3.07Å; N324-R328 PolarHBondContact O-NE 2.91Å
325L94.4Very high92.5Very high4 Ų453.7 Ų53.72%0.02128%0.283CS..Hα-helixtrans-75.8-53.7174.3-70.5171.3000110.3M261 E265 L268 I296 F303 R321 M322 Y323 S327 R328M261-L325 HydrophobicContact CB-CD1 3.69Å; M261-L325 HydrophobicContact CG-CD1 3.83Å; M261-L325 HydrophobicContact SD-CD1 4.38Å; E265-L325 HydrophobicContact CB-CD2 4.32Å; L268-L325 HydrophobicContact CD1-CD2 4.07Å; I296-L325 HydrophobicContact CD1-CB 4.19Å; I296-L325 HydrophobicContact CD1-CD2 4.2Å; I296-L325 HydrophobicContact CG1-CB 4.49Å; F303-L325 HydrophobicContact CE2-CD1 4.38Å; R321-L325 HydrophobicContact CG-CD1 4.38Å; R321-L325 WeakPolarHBondContact O-CG 3.39Å; R321-L325 PolarHBondContact O-N 3.31Å; M322-L325 PolarHBondContact O-N 3.3Å; Y323-L325 VanDerWaalsContact C-N 3.27Å; Y323-L325 PolarHBondContact O-N 2.98Å; L325-S327 VanDerWaalsContact C-N 3.29Å; L325-S327 PolarHBondContact O-N 3.23Å; L325-R328 WeakPolarHBondContact O-CB 3.46Å; L325-R328 PolarHBondContact O-N 3.46Å
326V94.5Very high92.5Very high0 Ų049 Ų490%026%0.262CS..Hα-helixtrans-69.9-26.8-175-179.30000112.2I296 L300 F303 M322 Y323 R328 I329 G332 L333 L336I296-V326 HydrophobicContact CG2-CG2 4.33Å; L300-V326 HydrophobicContact CD2-CG1 3.97Å; L300-V326 HydrophobicContact CD2-CG2 4.01Å; F303-V326 HydrophobicContact CD2-CG2 3.76Å; F303-V326 HydrophobicContact CE2-CG2 4.41Å; M322-V326 HydrophobicContact CG-CG2 4.23Å; M322-V326 WeakPolarHBondContact O-CG2 3.39Å; M322-V326 PolarHBondContact O-N 3.16Å; Y323-V326 PolarHBondContact O-N 3.47Å; V326-R328 PolarHBondContact O-N 3.35Å; V326-R328 VanDerWaalsContact O-N 3.11Å; V326-I329 PolarHBondContact O-N 3.43Å; V326-G332 WeakPolarHBondContact CG1-O 3.29Å; V326-L333 HydrophobicContact CB-CD2 4.01Å; V326-L333 HydrophobicContact CG1-CD2 3.86Å; V326-L333 HydrophobicContact CG1-CG 4.45Å; V326-L336 HydrophobicContact CB-CD1 4.05Å; V326-L336 HydrophobicContact CG1-CD1 4.01Å; V326-L336 HydrophobicContact CG2-CD1 4.16Å
327S93.9Very high92.7Very high54 Ų5448.2 Ų48.238%0.37826%0.256SS..THydrogen-bonded Turntrans-62.5-17.1175.866.70000113.8Y323 N324 L325 I329Y323-S327 WeakPolarHBondContact O-CB 3.49Å; Y323-S327 PolarHBondContact O-N 2.96Å; Y323-S327 PolarHBondContact O-OG 3.4Å; N324-S327 PolarHBondContact O-OG 3.07Å; L325-S327 VanDerWaalsContact C-N 3.29Å; L325-S327 PolarHBondContact O-N 3.23Å; S327-I329 VanDerWaalsContact C-N 3.32Å
328R91.6Very high92.8Very high125 Ų12545.6 Ų45.647%0.47224%0.242SC..THydrogen-bonded Turntrans-76.3-23.3175.3-61170-179.6-88.7-1.3112.3E292 N324 L325 V326E292-R328 HydrophobicContact CG-CB 4.33Å; E292-R328 IonicContact OE1-NH1 3.44Å; N324-R328 PolarHBondContact O-NE 2.91Å; L325-R328 WeakPolarHBondContact O-CB 3.46Å; L325-R328 PolarHBondContact O-N 3.46Å; V326-R328 PolarHBondContact O-N 3.35Å; V326-R328 VanDerWaalsContact O-N 3.11Å
329I91.5Very high92.8Very high20 Ų2046.3 Ų46.310%0.10325%0.246CC..SBendtrans-88.9128.7-179.9-53.4-57.1000109.5E292 I296 E297 L300 V326 S327 D331 G332E292-I329 HydrophobicContact CB-CD1 3.82Å; I296-I329 HydrophobicContact CB-CD1 4.2Å; I296-I329 HydrophobicContact CB-CG1 4.15Å; I296-I329 HydrophobicContact CG2-CD1 4.33Å; I296-I329 HydrophobicContact CG2-CG1 3.73Å; E297-I329 HydrophobicContact CB-CD1 4.23Å; E297-I329 HydrophobicContact CG-CG2 4.26Å; L300-I329 HydrophobicContact CD1-CG2 4.46Å; V326-I329 PolarHBondContact O-N 3.43Å; S327-I329 VanDerWaalsContact C-N 3.32Å; I329-D331 PolarHBondContact O-N 2.9Å; I329-G332 PolarHBondContact O-N 3.41Å; I329-G332 VanDerWaalsContact O-N 3.16Å
330T85.4Confident92.9Very high124 Ų12446.3 Ų46.376%0.76125%0.246SC*.THydrogen-bonded Turntrans-56.1125.7172.7-47.20000109.8G332T330-G332 PolarHBondContact O-N 3.19Å
331D83.5Confident92.9Very high153 Ų15346.8 Ų46.882%0.81825%0.245SC*.THydrogen-bonded Turntrans59.69.3-178.4-60.5-41000116.6I329 L333 G334I329-D331 PolarHBondContact O-N 2.9Å; D331-L333 VanDerWaalsContact C-N 3.3Å; D331-L333 PolarHBondContact O-N 3.29Å; D331-G334 PolarHBondContact O-N 3.36Å
332G86.5Confident93Very high8 Ų847.7 Ų47.78%0.08226%0.255CS..THydrogen-bonded Turntrans-66.5-27-17900000114.5V326 I329 T330 G334V326-G332 WeakPolarHBondContact CG1-O 3.29Å; I329-G332 PolarHBondContact O-N 3.41Å; I329-G332 VanDerWaalsContact O-N 3.16Å; T330-G332 PolarHBondContact O-N 3.19Å; G332-G334 VanDerWaalsContact C-N 3.26Å; G332-G334 PolarHBondContact O-N 2.84Å
333L92.1Very high93Very high23 Ų2347.9 Ų47.912%0.1226%0.257CS..Hα-helixtrans-76.3-8.4-177.2-63.2176.5000114Y323 V326 D331 L336 K337 F391Y323-L333 HydrophobicContact CD2-CD1 4.45Å; Y323-L333 HydrophobicContact CD2-CD2 3.96Å; Y323-L333 HydrophobicContact CE2-CD1 3.94Å; Y323-L333 HydrophobicContact CE2-CD2 4.29Å; V326-L333 HydrophobicContact CB-CD2 4.01Å; V326-L333 HydrophobicContact CG1-CD2 3.86Å; V326-L333 HydrophobicContact CG1-CG 4.45Å; D331-L333 VanDerWaalsContact C-N 3.3Å; D331-L333 PolarHBondContact O-N 3.29Å; L333-L336 HydrophobicContact CD2-CD1 4.09Å; L333-L336 PolarHBondContact O-N 3.22Å; L333-K337 WeakPolarHBondContact O-CG 3.2Å; L333-K337 PolarHBondContact O-N 3.15Å; L333-K337 VanDerWaalsContact O-N 3.1Å; L333-F391 HydrophobicContact CD1-CE2 4.48Å; L333-F391 HydrophobicContact CD2-CE2 4.23Å
334G92.2Very high93.1Very high42 Ų4246.9 Ų46.943%0.43325%0.252SS..Hα-helixtrans-58.8-50.5-173.300000113.5D331 G332 K337 K338D331-G334 PolarHBondContact O-N 3.36Å; G332-G334 VanDerWaalsContact C-N 3.26Å; G332-G334 PolarHBondContact O-N 2.84Å; G334-K337 PolarHBondContact O-N 3.05Å; G334-K338 PolarHBondContact O-N 3.15Å
335E92.6Very high93.1Very high84 Ų8445.3 Ų45.339%0.39324%0.243SC..Hα-helixtrans-71.9-34.9179.5-72.3-61.5133.200112.1K337 K338 L339E335-K337 VanDerWaalsContact C-N 3.31Å; E335-K337 PolarHBondContact O-N 2.93Å; E335-K338 WeakPolarHBondContact O-CB 3.47Å; E335-K338 PolarHBondContact O-N 3.01Å; E335-K338 VanDerWaalsContact O-N 3.14Å; E335-K338 IonicContact OE1-NZ 2.64Å; E335-K338 PolarHBondContact OE1-NZ 3Å; E335-K338 IonicContact OE2-NZ 3.85Å; E335-K338 PolarHBondContact OE2-NZ 3.11Å; E335-L339 WeakPolarHBondContact O-CG 3.32Å; E335-L339 PolarHBondContact O-N 3.12Å
336L94.6Very high93.1Very high0 Ų049.2 Ų49.20%026%0.264CS..Hα-helixtrans-59.9-40.9175.3-61.6-170.8000112.2F307 M322 V326 L333 K338 L339 L340 F391F307-L336 HydrophobicContact CB-CD2 3.86Å; F307-L336 HydrophobicContact CD1-CD2 3.88Å; F307-L336 HydrophobicContact CD2-CD2 3.91Å; F307-L336 HydrophobicContact CE1-CB 4.23Å; F307-L336 HydrophobicContact CE1-CD2 4.35Å; F307-L336 WeakPolarHBondContact CE1-O 3.04Å; F307-L336 HydrophobicContact CE2-CD1 4.47Å; F307-L336 HydrophobicContact CE2-CD2 4.38Å; F307-L336 HydrophobicContact CG-CD2 3.63Å; F307-L336 HydrophobicContact CZ-CB 4.24Å; M322-L336 HydrophobicContact SD-CD2 4.41Å; V326-L336 HydrophobicContact CB-CD1 4.05Å; V326-L336 HydrophobicContact CG1-CD1 4.01Å; V326-L336 HydrophobicContact CG2-CD1 4.16Å; L333-L336 HydrophobicContact CD2-CD1 4.09Å; L333-L336 PolarHBondContact O-N 3.22Å; L336-K338 VanDerWaalsContact C-N 3.33Å; L336-K338 PolarHBondContact O-N 2.92Å; L336-L339 HydrophobicContact CD2-CD1 4.49Å; L336-L339 PolarHBondContact O-N 3.3Å; L336-L340 PolarHBondContact O-N 3.41Å; L336-F391 HydrophobicContact CB-CE1 4.2Å; L336-F391 HydrophobicContact CB-CZ 3.82Å
337K95.3Very high93.2Very high53 Ų5352.8 Ų52.823%0.2328%0.281CS..Hα-helixtrans-61.4-41.7175.7-72.1167.5-178.9179.40111.6L333 G334 E335 L340 E341 D388 F391 A394L333-K337 WeakPolarHBondContact O-CG 3.2Å; L333-K337 PolarHBondContact O-N 3.15Å; L333-K337 VanDerWaalsContact O-N 3.1Å; G334-K337 PolarHBondContact O-N 3.05Å; E335-K337 VanDerWaalsContact C-N 3.31Å; E335-K337 PolarHBondContact O-N 2.93Å; K337-L340 PolarHBondContact O-N 2.87Å; K337-E341 PolarHBondContact O-N 3.44Å; K337-D388 WeakPolarHBondContact CE-OD1 3.39Å; K337-D388 IonicContact NZ-OD1 3.91Å; K337-D388 PolarHBondContact NZ-OD1 3.3Å; K337-D388 VanDerWaalsContact NZ-OD1 3.1Å; K337-F391 HydrophobicContact CG-CD1 3.94Å; K337-F391 HydrophobicContact CG-CD2 3.97Å; K337-F391 HydrophobicContact CG-CE1 3.91Å; K337-F391 HydrophobicContact CG-CE2 3.9Å; K337-F391 HydrophobicContact CG-CG 4.02Å; K337-F391 HydrophobicContact CG-CZ 3.9Å; K337-A394 HydrophobicContact CB-CB 4.43Å; K337-A394 WeakPolarHBondContact O-CB 3.35Å
338K95.3Very high93.1Very high108 Ų10850.2 Ų50.247%0.4726%0.263SS..Hα-helixtrans-70.4-38.2178.7178.1-178.6158.6-150.60112.6G334 E335 L336 E341 T342G334-K338 PolarHBondContact O-N 3.15Å; E335-K338 WeakPolarHBondContact O-CB 3.47Å; E335-K338 PolarHBondContact O-N 3.01Å; E335-K338 VanDerWaalsContact O-N 3.14Å; E335-K338 IonicContact OE1-NZ 2.64Å; E335-K338 PolarHBondContact OE1-NZ 3Å; E335-K338 IonicContact OE2-NZ 3.85Å; E335-K338 PolarHBondContact OE2-NZ 3.11Å; L336-K338 VanDerWaalsContact C-N 3.33Å; L336-K338 PolarHBondContact O-N 2.92Å; K338-E341 PolarHBondContact O-N 2.91Å; K338-T342 WeakPolarHBondContact O-CB 3.36Å; K338-T342 PolarHBondContact O-N 3.23Å; K338-T342 PolarHBondContact O-OG1 3.36Å
339L95.2Very high93.2Very high39 Ų3946.1 Ų46.120%0.20425%0.25CC..Hα-helixtrans-62.8-46.5172.3-72.1173.8000110.6H304 F307 E335 L336 E341 T342 H343H304-L339 HydrophobicContact CB-CD1 4.06Å; H304-L339 VanDerWaalsContact O-CD1 3.32Å; H304-L339 WeakPolarHBondContact O-CD1 3.32Å; F307-L339 HydrophobicContact CB-CD1 4.41Å; F307-L339 HydrophobicContact CD1-CB 3.84Å; F307-L339 HydrophobicContact CD1-CD1 3.96Å; F307-L339 HydrophobicContact CE1-CB 4.06Å; E335-L339 WeakPolarHBondContact O-CG 3.32Å; E335-L339 PolarHBondContact O-N 3.12Å; L336-L339 HydrophobicContact CD2-CD1 4.49Å; L336-L339 PolarHBondContact O-N 3.3Å; L339-E341 PolarHBondContact O-N 3.01Å; L339-T342 PolarHBondContact O-N 3.47Å; L339-H343 WeakPolarHBondContact O-CB 3.4Å; L339-H343 PolarHBondContact O-N 3.49Å
340L96.3Very high93.3Very high0 Ų047.4 Ų47.40%026%0.264CS..Hα-helixtrans-60-47.4175.3-174.572.3000111.5F307 L311 L336 K337 T342 H343 I344 L380 V381 F385 F391F307-L340 HydrophobicContact CE1-CB 4.32Å; L311-L340 HydrophobicContact CD1-CD1 4.29Å; L311-L340 HydrophobicContact CD2-CD1 3.63Å; L336-L340 PolarHBondContact O-N 3.41Å; K337-L340 PolarHBondContact O-N 2.87Å; L340-T342 VanDerWaalsContact C-N 3.26Å; L340-T342 PolarHBondContact O-N 2.93Å; L340-H343 PolarHBondContact O-N 3.1Å; L340-I344 HydrophobicContact CD1-CD1 3.89Å; L340-I344 HydrophobicContact CD1-CG1 4.1Å; L340-I344 HydrophobicContact CD2-CD1 3.99Å; L340-I344 HydrophobicContact CG-CD1 3.59Å; L340-I344 HydrophobicContact CG-CG1 4.16Å; L340-I344 WeakPolarHBondContact O-CB 3.32Å; L340-I344 VanDerWaalsContact O-CG1 3.24Å; L340-I344 WeakPolarHBondContact O-CG1 3.4Å; L340-I344 PolarHBondContact O-N 3.46Å; L340-L380 HydrophobicContact CD1-CD2 4.11Å; L340-V381 HydrophobicContact CD2-CG2 4.05Å; L340-F385 HydrophobicContact CD1-CE2 4.3Å; L340-F385 HydrophobicContact CD2-CD2 4.31Å; L340-F385 HydrophobicContact CD2-CE2 3.89Å; L340-F391 HydrophobicContact CB-CD1 4.35Å; L340-F391 HydrophobicContact CB-CE1 4.4Å; L340-F391 HydrophobicContact CD2-CB 4.49Å; L340-F391 HydrophobicContact CD2-CD1 3.56Å; L340-F391 HydrophobicContact CD2-CE1 4.3Å
341E96.4Very high93.7Very high19 Ų1942.8 Ų42.89%0.08924%0.238CC..Hα-helixtrans-53.8-46.6176.8-175.9-169.7147.200111K337 K338 L339 H345 A394 K397 A398 R401K337-E341 PolarHBondContact O-N 3.44Å; K338-E341 PolarHBondContact O-N 2.91Å; L339-E341 PolarHBondContact O-N 3.01Å; E341-H345 WeakPolarHBondContact O-CB 3.4Å; E341-H345 PolarHBondContact O-N 3.39Å; E341-A394 HydrophobicContact CB-CB 4.18Å; E341-K397 VanDerWaalsContact CD-NZ 3.33Å; E341-K397 WeakPolarHBondContact OE1-CD 3.33Å; E341-K397 WeakPolarHBondContact OE1-CE 3.26Å; E341-K397 IonicContact OE1-NZ 3.83Å; E341-K397 PolarHBondContact OE1-NZ 3.45Å; E341-K397 VanDerWaalsContact OE1-NZ 3.07Å; E341-K397 WeakPolarHBondContact OE2-CD 3.4Å; E341-K397 WeakPolarHBondContact OE2-CE 3.24Å; E341-K397 IonicContact OE2-NZ 3.97Å; E341-K397 PolarHBondContact OE2-NZ 3.08Å; E341-A398 HydrophobicContact CG-CB 4.09Å; E341-A398 WeakPolarHBondContact O-CB 3.46Å; E341-R401 IonicContact OE1-NH1 2.86Å; E341-R401 PolarHBondContact OE1-NH1 3.25Å
342T96.4Very high94.1Very high61 Ų6135.7 Ų35.737%0.37420%0.2SC..Hα-helixtrans-68.5-44.4-177.5-550000111.7K338 L339 L340 H345 N346K338-T342 WeakPolarHBondContact O-CB 3.36Å; K338-T342 PolarHBondContact O-N 3.23Å; K338-T342 PolarHBondContact O-OG1 3.36Å; L339-T342 PolarHBondContact O-N 3.47Å; L340-T342 VanDerWaalsContact C-N 3.26Å; L340-T342 PolarHBondContact O-N 2.93Å; T342-H345 PolarHBondContact O-N 3.31Å; T342-N346 VanDerWaalsContact O-CG 3.25Å; T342-N346 PolarHBondContact O-N 3.11Å; T342-N346 PolarHBondContact O-ND2 2.96Å
343H96.1Very high94.2Very high5 Ų540.8 Ų40.82%0.02322%0.222CC..Hα-helixtrans-63.3-47.2178173.990.6000111.4Q308 L311 D312 L339 L340 H345 N346 Q347 Y377Q308-H343 PolarHBondContact NE2-ND1 3.41Å; L311-H343 HydrophobicContact CD1-CB 3.93Å; D312-H343 IonicContact OD1-CE1 2.85Å; D312-H343 PolarHBondContact OD1-CE1 3.11Å; D312-H343 IonicContact OD1-ND1 3Å; D312-H343 PolarHBondContact OD1-ND1 3.39Å; L339-H343 WeakPolarHBondContact O-CB 3.4Å; L339-H343 PolarHBondContact O-N 3.49Å; L340-H343 PolarHBondContact O-N 3.1Å; H343-H345 VanDerWaalsContact C-N 3.3Å; H343-H345 PolarHBondContact O-N 2.81Å; H343-N346 PolarHBondContact O-N 2.86Å; H343-Q347 WeakPolarHBondContact O-CB 3.24Å; H343-Q347 VanDerWaalsContact O-CG 3.24Å; H343-Q347 WeakPolarHBondContact O-CG 3.36Å; H343-Q347 PolarHBondContact O-N 3.38Å; H343-Y377 AromaticContact CD2-CE1 3.66Å; H343-Y377 AromaticContact CD2-CZ 3.79Å; H343-Y377 PolarHBondContact CD2-OH 2.92Å; H343-Y377 AromaticContact NE2-CE1 3.63Å; H343-Y377 AromaticContact NE2-CZ 3.61Å; H343-Y377 PolarHBondContact NE2-OH 3.32Å
344I96.3Very high94.1Very high0 Ų048.8 Ų48.80%026%0.256CS..Hα-helixtrans-60.5-42.4177.2-64.7172.5000110.7L340 Q347 G348 Y377 L395 A398 F402L340-I344 HydrophobicContact CD1-CD1 3.89Å; L340-I344 HydrophobicContact CD1-CG1 4.1Å; L340-I344 HydrophobicContact CD2-CD1 3.99Å; L340-I344 HydrophobicContact CG-CD1 3.59Å; L340-I344 HydrophobicContact CG-CG1 4.16Å; L340-I344 WeakPolarHBondContact O-CB 3.32Å; L340-I344 VanDerWaalsContact O-CG1 3.24Å; L340-I344 WeakPolarHBondContact O-CG1 3.4Å; L340-I344 PolarHBondContact O-N 3.46Å; I344-Q347 PolarHBondContact O-N 2.81Å; I344-G348 PolarHBondContact O-N 3.3Å; I344-Y377 HydrophobicContact CB-CD2 4.39Å; I344-Y377 HydrophobicContact CD1-CD1 4.14Å; I344-Y377 HydrophobicContact CD1-CG 3.92Å; I344-Y377 HydrophobicContact CG1-CD1 3.69Å; I344-Y377 HydrophobicContact CG1-CD2 3.88Å; I344-Y377 HydrophobicContact CG1-CE1 4.06Å; I344-Y377 HydrophobicContact CG1-CE2 4.24Å; I344-Y377 HydrophobicContact CG1-CG 3.6Å; I344-Y377 HydrophobicContact CG2-CD2 4.02Å; I344-Y377 HydrophobicContact CG2-CE2 4.5Å; I344-Y377 HydrophobicContact CG2-CG 4.44Å; I344-L395 HydrophobicContact CD1-CB 4.24Å; I344-L395 HydrophobicContact CD1-CD1 3.78Å; I344-L395 HydrophobicContact CG2-CD1 4.27Å; I344-A398 HydrophobicContact CB-CB 3.69Å; I344-A398 HydrophobicContact CG2-CB 3.58Å; I344-F402 HydrophobicContact CG2-CE1 4.48Å
345H95.5Very high93.9Very high30 Ų3048.5 Ų48.514%0.13925%0.247CC..Hα-helixtrans-59.2-49.2177.1179.760.2000111.6E341 T342 H343 G348 L349 A398E341-H345 WeakPolarHBondContact O-CB 3.4Å; E341-H345 PolarHBondContact O-N 3.39Å; T342-H345 PolarHBondContact O-N 3.31Å; H343-H345 VanDerWaalsContact C-N 3.3Å; H343-H345 PolarHBondContact O-N 2.81Å; H345-G348 PolarHBondContact O-N 2.85Å; H345-L349 WeakPolarHBondContact O-CG 3.24Å; H345-L349 PolarHBondContact O-N 3.46Å; H345-A398 HydrophobicContact CB-CB 4.48Å
346N95.1Very high93.2Very high86 Ų8646 Ų4646%0.4624%0.243SC..Hα-helixtrans-65.5-40.6-179.7-68.2-18.4000112.3T342 H343 L349 A350T342-N346 VanDerWaalsContact O-CG 3.25Å; T342-N346 PolarHBondContact O-N 3.11Å; T342-N346 PolarHBondContact O-ND2 2.96Å; H343-N346 PolarHBondContact O-N 2.86Å; N346-L349 PolarHBondContact O-N 3.24Å; N346-A350 WeakPolarHBondContact O-CB 3.44Å; N346-A350 PolarHBondContact O-N 3.48Å
347Q94.6Very high92.5Very high74 Ų7452.6 Ų52.635%0.34627%0.274SS..Hα-helixtrans-68.6-38.8178.4-71-75.5-1100111.9H343 I344 A350 A351 Y377H343-Q347 WeakPolarHBondContact O-CB 3.24Å; H343-Q347 VanDerWaalsContact O-CG 3.24Å; H343-Q347 WeakPolarHBondContact O-CG 3.36Å; H343-Q347 PolarHBondContact O-N 3.38Å; I344-Q347 PolarHBondContact O-N 2.81Å; Q347-A350 PolarHBondContact O-N 3.41Å; Q347-A351 VanDerWaalsContact O-CB 3.29Å; Q347-A351 WeakPolarHBondContact O-CB 3.21Å; Q347-A351 PolarHBondContact O-N 3.14Å; Q347-Y377 HydrophobicContact CB-CE2 4.15Å; Q347-Y377 WeakPolarHBondContact CB-OH 3.36Å; Q347-Y377 VanDerWaalsContact CG-OH 3.26Å; Q347-Y377 WeakPolarHBondContact CG-OH 3.48Å
348G93.7Very high92.1Very high0 Ų052.6 Ų52.60%028%0.284CS..Hα-helixtrans-61.5-42.4171.700000112.6I344 H345 I352I344-G348 PolarHBondContact O-N 3.3Å; H345-G348 PolarHBondContact O-N 2.85Å; G348-I352 WeakPolarHBondContact O-CG1 3.4Å; G348-I352 PolarHBondContact O-N 3.16Å
349L93.4Very high91.4Very high39 Ų3947.5 Ų47.520%0.20426%0.262CS..Hα-helixtrans-62.3-49.5174.3-71.9177.8000112H345 N346 A351 I352 E353 F402 N405 N406H345-L349 WeakPolarHBondContact O-CG 3.24Å; H345-L349 PolarHBondContact O-N 3.46Å; N346-L349 PolarHBondContact O-N 3.24Å; L349-A351 VanDerWaalsContact C-N 3.34Å; L349-A351 PolarHBondContact O-N 3.05Å; L349-I352 PolarHBondContact O-N 3.26Å; L349-E353 VanDerWaalsContact O-CB 3.31Å; L349-E353 WeakPolarHBondContact O-CB 3.3Å; L349-E353 PolarHBondContact O-N 3.18Å; L349-F402 HydrophobicContact CD2-CB 4.27Å; L349-F402 HydrophobicContact CG-CB 4.3Å; L349-N405 WeakPolarHBondContact CD2-O 3.33Å; L349-N406 HydrophobicContact CD2-CB 3.97Å
350A93.6Very high90.8Very high48 Ų4847.3 Ų47.340%0.39726%0.261SS..Hα-helixtrans-62.7-39.5-179.300000112.1N346 Q347 E353 K354N346-A350 WeakPolarHBondContact O-CB 3.44Å; N346-A350 PolarHBondContact O-N 3.48Å; Q347-A350 PolarHBondContact O-N 3.41Å; A350-E353 PolarHBondContact O-N 3.45Å; A350-K354 WeakPolarHBondContact O-CB 3.15Å; A350-K354 PolarHBondContact O-N 3.21Å
351A93Very high90.1Very high27 Ų2753.1 Ų53.122%0.22329%0.292CS..Hα-helixtrans-62.7-44177.200000112Q347 L349 C355 T369 V373Q347-A351 VanDerWaalsContact O-CB 3.29Å; Q347-A351 WeakPolarHBondContact O-CB 3.21Å; Q347-A351 PolarHBondContact O-N 3.14Å; L349-A351 VanDerWaalsContact C-N 3.34Å; L349-A351 PolarHBondContact O-N 3.05Å; A351-C355 PolarHBondContact O-SG 2.89Å; A351-T369 HydrophobicContact CB-CG2 3.88Å; A351-V373 HydrophobicContact CB-CG2 3.72Å
352I91.4Very high89.7Confident4 Ų455.6 Ų55.62%0.02131%0.306CS..Hα-helixtrans-69.7-40.3177-65.2172.4000110.8G348 L349 K354 C355 Y366 F402 N406 A407 V408G348-I352 WeakPolarHBondContact O-CG1 3.4Å; G348-I352 PolarHBondContact O-N 3.16Å; L349-I352 PolarHBondContact O-N 3.26Å; I352-K354 PolarHBondContact O-N 2.96Å; I352-C355 WeakPolarHBondContact O-CB 3.3Å; I352-C355 PolarHBondContact O-N 3.14Å; I352-Y366 HydrophobicContact CD1-CE2 4.15Å; I352-Y366 HydrophobicContact CG2-CE2 4.32Å; I352-F402 HydrophobicContact CD1-CD2 3.9Å; I352-F402 HydrophobicContact CD1-CE2 4.16Å; I352-N406 HydrophobicContact CD1-CB 3.85Å; I352-N406 HydrophobicContact CG2-CB 4.15Å; I352-A407 HydrophobicContact CG2-CB 4.48Å; I352-V408 HydrophobicContact CG2-CG2 3.81Å
353E89.7Confident89.5Confident114 Ų11453.8 Ų53.853%0.53330%0.296SS..Hα-helixtrans-63.9-39.6178.5-174.8162.7-143.800112.3L349 A350 C355 G356 A407L349-E353 VanDerWaalsContact O-CB 3.31Å; L349-E353 WeakPolarHBondContact O-CB 3.3Å; L349-E353 PolarHBondContact O-N 3.18Å; A350-E353 PolarHBondContact O-N 3.45Å; E353-C355 PolarHBondContact O-N 3.34Å; E353-G356 PolarHBondContact O-N 2.78Å; E353-A407 HydrophobicContact CB-CB 4.25Å
354K90.3Very high89.3Confident192 Ų19259.5 Ų59.584%0.83532%0.32SS*.Hα-helixtrans-60-28.4174.8-173176.6179.8179.70113A350 I352 G356A350-K354 WeakPolarHBondContact O-CB 3.15Å; A350-K354 PolarHBondContact O-N 3.21Å; I352-K354 PolarHBondContact O-N 2.96Å; K354-G356 VanDerWaalsContact C-N 3.3Å
355C86.6Confident89.1Confident36 Ų3661.8 Ų61.824%0.24333%0.334CS..THydrogen-bonded Turntrans-77.2-15.8176.2-61.60000113.1A351 I352 E353 A358 A359 V365 T369A351-C355 PolarHBondContact O-SG 2.89Å; I352-C355 WeakPolarHBondContact O-CB 3.3Å; I352-C355 PolarHBondContact O-N 3.14Å; E353-C355 PolarHBondContact O-N 3.34Å; C355-A358 WeakPolarHBondContact O-CB 3.46Å; C355-A358 PolarHBondContact O-N 3.34Å; C355-A359 HydrophobicContact CB-CB 3.69Å; C355-V365 HydrophobicContact CB-CG1 4.21Å; C355-T369 PolarHBondContact SG-OG1 3.25Å
356G79.4Confident89Confident31 Ų3160.5 Ų60.532%0.3233%0.328SS..Hα-helixtrans52.2-138.5175.300000114.2E353 K354 A358 A359E353-G356 PolarHBondContact O-N 2.78Å; K354-G356 VanDerWaalsContact C-N 3.3Å; G356-A358 PolarHBondContact O-N 2.97Å; G356-A359 PolarHBondContact O-N 3.15Å
357E80.1Confident88.9Confident138 Ų13856.4 Ų56.465%0.64531%0.306SS*.Hα-helixtrans-64.7-21.4179.5-70.2-174.1176.900114A359 L360 N361 M411E357-A359 VanDerWaalsContact C-N 3.31Å; E357-A359 PolarHBondContact O-N 3.46Å; E357-L360 WeakPolarHBondContact O-CB 3.36Å; E357-L360 PolarHBondContact O-N 3.49Å; E357-L360 VanDerWaalsContact O-N 3.14Å; E357-N361 PolarHBondContact O-N 3.49Å; E357-M411 HydrophobicContact CG-CE 3.9Å
358A85.4Confident88.8Confident54 Ų5455.7 Ų55.745%0.44630%0.303SS..Hα-helixtrans-62.9-40.9178.500000110.9C355 G356 L360 N361 D362C355-A358 WeakPolarHBondContact O-CB 3.46Å; C355-A358 PolarHBondContact O-N 3.34Å; G356-A358 PolarHBondContact O-N 2.97Å; A358-L360 VanDerWaalsContact C-N 3.26Å; A358-L360 PolarHBondContact O-N 2.89Å; A358-N361 PolarHBondContact O-N 3.03Å; A358-D362 WeakPolarHBondContact O-CA 2.97Å; A358-D362 VanDerWaalsContact O-CB 3.29Å; A358-D362 WeakPolarHBondContact O-CB 3.44Å; A358-D362 PolarHBondContact O-N 3.43Å
359A81.1Confident88.8Confident1 Ų157 Ų571%0.00831%0.311CS..Hα-helixtrans-69-21.9177.100000113.6C355 G356 E357 Y366 V408 L421C355-A359 HydrophobicContact CB-CB 3.69Å; G356-A359 PolarHBondContact O-N 3.15Å; E357-A359 VanDerWaalsContact C-N 3.31Å; E357-A359 PolarHBondContact O-N 3.46Å; A359-Y366 HydrophobicContact CB-CD2 4.35Å; A359-V408 HydrophobicContact CB-CG2 3.88Å; A359-L421 WeakPolarHBondContact O-CD1 3.44Å
360L81.8Confident88.9Confident35 Ų3555.1 Ų55.118%0.18330%0.301CS..Hα-helixtrans-73.3-34.8176.5-178.666.7000112E357 A358 V408 M411 A412 K417E357-L360 WeakPolarHBondContact O-CB 3.36Å; E357-L360 PolarHBondContact O-N 3.49Å; E357-L360 VanDerWaalsContact O-N 3.14Å; A358-L360 VanDerWaalsContact C-N 3.26Å; A358-L360 PolarHBondContact O-N 2.89Å; L360-V408 HydrophobicContact CD1-CG1 3.83Å; L360-M411 HydrophobicContact CD2-CE 4.31Å; L360-A412 HydrophobicContact CD1-CB 4.39Å; L360-K417 HydrophobicContact CD1-CG 4.34Å
361N82.4Confident88.9Confident122 Ų12253 Ų5365%0.65228%0.283SS*.Hα-helixtrans-108-23.2-170.8-66.8-41.7000113.7E357 A358 P363E357-N361 PolarHBondContact O-N 3.49Å; A358-N361 PolarHBondContact O-N 3.03Å; N361-P363 WeakPolarHBondContact O-CD 3.41Å
362D88.9Confident89Confident71 Ų7155.6 Ų55.638%0.3829%0.293SS..  trans-108102.7177.2-168.7-21.1000111.1A358 K364 V365 Y366A358-D362 WeakPolarHBondContact O-CA 2.97Å; A358-D362 VanDerWaalsContact O-CB 3.29Å; A358-D362 WeakPolarHBondContact O-CB 3.44Å; A358-D362 PolarHBondContact O-N 3.43Å; D362-K364 PolarHBondContact O-N 3.32Å; D362-K364 VanDerWaalsContact OD1-CB 3.31Å; D362-K364 WeakPolarHBondContact OD1-CB 3.32Å; D362-K364 PolarHBondContact OD1-N 3.48Å; D362-V365 HydrophobicContact CB-CB 4.16Å; D362-V365 HydrophobicContact CB-CG2 3.96Å; D362-V365 PolarHBondContact O-N 3.19Å; D362-V365 WeakPolarHBondContact OD2-CG2 3.45Å; D362-Y366 PolarHBondContact O-N 3.29Å
363P90.8Very high89.2Confident23 Ų2356.1 Ų56.115%0.14930%0.296CS..Hα-helixtrans-55.4-33.5175.8-26.735.4000114.2N361 V367 L421 R424N361-P363 WeakPolarHBondContact O-CD 3.41Å; P363-V367 VanDerWaalsContact O-CG2 3.31Å; P363-V367 WeakPolarHBondContact O-CG2 3.45Å; P363-V367 PolarHBondContact O-N 3.19Å; P363-V367 VanDerWaalsContact O-N 3.07Å; P363-L421 HydrophobicContact CB-CD2 4.48Å; P363-L421 WeakPolarHBondContact CB-O 3.44Å; P363-L421 HydrophobicContact CG-CD2 4.08Å; P363-R424 HydrophobicContact CB-CB 4.11Å; P363-R424 HydrophobicContact CG-CB 3.61Å
364K91.6Very high89.5Confident125 Ų12551.8 Ų51.854%0.54328%0.276SS..Hα-helixtrans-68.9-45.7-177.6-179.4174.5-178.3179.60110.7D362 Y366 V367 Q368 Y425D362-K364 PolarHBondContact O-N 3.32Å; D362-K364 VanDerWaalsContact OD1-CB 3.31Å; D362-K364 WeakPolarHBondContact OD1-CB 3.32Å; D362-K364 PolarHBondContact OD1-N 3.48Å; K364-Y366 VanDerWaalsContact C-N 3.34Å; K364-Y366 PolarHBondContact O-N 3.01Å; K364-V367 PolarHBondContact O-N 3.01Å; K364-Q368 WeakPolarHBondContact O-CB 3.31Å; K364-Q368 PolarHBondContact O-N 3.14Å; K364-Y425 HydrophobicContact CB-CD2 3.92Å; K364-Y425 HydrophobicContact CB-CE2 3.7Å; K364-Y425 HydrophobicContact CD-CE2 4.39Å; K364-Y425 HydrophobicContact CG-CD2 4.42Å; K364-Y425 HydrophobicContact CG-CE2 3.69Å
365V92.9Very high89.7Confident48 Ų4846.9 Ų46.929%0.29126%0.255SS..Hα-helixtrans-60.5-45.5178.1174.10000110.6C355 D362 T369C355-V365 HydrophobicContact CB-CG1 4.21Å; D362-V365 HydrophobicContact CB-CB 4.16Å; D362-V365 HydrophobicContact CB-CG2 3.96Å; D362-V365 PolarHBondContact O-N 3.19Å; D362-V365 WeakPolarHBondContact OD2-CG2 3.45Å; V365-T369 VanDerWaalsContact O-CB 3.31Å; V365-T369 WeakPolarHBondContact O-CB 3.44Å; V365-T369 PolarHBondContact O-N 3.37Å; V365-T369 PolarHBondContact O-OG1 3.5Å
366Y93Very high90.2Very high2 Ų249.4 Ų49.41%0.00826%0.262CS..Hα-helixtrans-61-51.2179.1179.2-95.5000112.8I352 A359 D362 K364 T370 I403 N406 V408 S418 L421I352-Y366 HydrophobicContact CD1-CE2 4.15Å; I352-Y366 HydrophobicContact CG2-CE2 4.32Å; A359-Y366 HydrophobicContact CB-CD2 4.35Å; D362-Y366 PolarHBondContact O-N 3.29Å; K364-Y366 VanDerWaalsContact C-N 3.34Å; K364-Y366 PolarHBondContact O-N 3.01Å; Y366-T370 PolarHBondContact O-N 2.88Å; Y366-T370 VanDerWaalsContact O-N 3.12Å; Y366-T370 PolarHBondContact O-OG1 3.22Å; Y366-I403 PolarHBondContact OH-O 2.95Å; Y366-N406 PolarHBondContact OH-ND2 3.24Å; Y366-N406 VanDerWaalsContact OH-ND2 3.08Å; Y366-V408 HydrophobicContact CD2-CB 4.48Å; Y366-V408 HydrophobicContact CD2-CG2 4.05Å; Y366-V408 HydrophobicContact CE2-CB 4.24Å; Y366-V408 HydrophobicContact CE2-CG2 4.19Å; Y366-S418 VanDerWaalsContact OH-CB 3.28Å; Y366-S418 WeakPolarHBondContact OH-CB 3.36Å; Y366-S418 PolarHBondContact OH-OG 3.21Å; Y366-L421 HydrophobicContact CD1-CB 4.14Å; Y366-L421 HydrophobicContact CD1-CD1 4.16Å; Y366-L421 HydrophobicContact CD2-CD1 4.15Å; Y366-L421 HydrophobicContact CG-CD1 3.89Å
367V93.5Very high90.9Very high0 Ų048.1 Ų48.10%025%0.247CC..Hα-helixtrans-68.6-41.9-176.5176.40000110.9P363 K364 T370 L371 L422 Y425 V452P363-V367 VanDerWaalsContact O-CG2 3.31Å; P363-V367 WeakPolarHBondContact O-CG2 3.45Å; P363-V367 PolarHBondContact O-N 3.19Å; P363-V367 VanDerWaalsContact O-N 3.07Å; K364-V367 PolarHBondContact O-N 3.01Å; V367-T370 PolarHBondContact O-N 3.32Å; V367-L371 HydrophobicContact CG1-CD1 3.88Å; V367-L371 HydrophobicContact CG1-CG 4.36Å; V367-L371 WeakPolarHBondContact O-CB 3.4Å; V367-L371 WeakPolarHBondContact O-CG 3.34Å; V367-L371 PolarHBondContact O-N 3.5Å; V367-L422 HydrophobicContact CG1-CD1 4.05Å; V367-L422 HydrophobicContact CG2-CD1 3.69Å; V367-Y425 HydrophobicContact CB-CD1 3.8Å; V367-Y425 HydrophobicContact CB-CE1 4.13Å; V367-Y425 HydrophobicContact CB-CG 4.19Å; V367-Y425 HydrophobicContact CG1-CD1 3.64Å; V367-Y425 HydrophobicContact CG1-CE1 3.74Å; V367-Y425 HydrophobicContact CG2-CD1 3.88Å; V367-Y425 HydrophobicContact CG2-CG 4.03Å; V367-V452 HydrophobicContact CG1-CG2 4.49Å
368Q92.9Very high91.6Very high60 Ų6044.3 Ų44.328%0.2823%0.231SC..Hα-helixtrans-63.6-45.8178.8-170.262.246.900111.7K364 T370 L371 D372K364-Q368 WeakPolarHBondContact O-CB 3.31Å; K364-Q368 PolarHBondContact O-N 3.14Å; Q368-T370 VanDerWaalsContact C-N 3.28Å; Q368-T370 PolarHBondContact O-N 3.22Å; Q368-L371 WeakPolarHBondContact O-CB 3.4Å; Q368-L371 PolarHBondContact O-N 2.89Å; Q368-L371 VanDerWaalsContact O-N 3.11Å; Q368-D372 PolarHBondContact NE2-OD1 3.33Å; Q368-D372 PolarHBondContact O-N 3.38Å
369T94.1Very high92.1Very high26 Ų2644.5 Ų44.516%0.1623%0.233CC..Hα-helixtrans-59.5-41.9177.6-55.20000111.4A351 C355 V365 D372 V373A351-T369 HydrophobicContact CB-CG2 3.88Å; C355-T369 PolarHBondContact SG-OG1 3.25Å; V365-T369 VanDerWaalsContact O-CB 3.31Å; V365-T369 WeakPolarHBondContact O-CB 3.44Å; V365-T369 PolarHBondContact O-N 3.37Å; V365-T369 PolarHBondContact O-OG1 3.5Å; T369-D372 PolarHBondContact O-N 3.27Å; T369-V373 WeakPolarHBondContact O-CG2 3.45Å; T369-V373 PolarHBondContact O-N 3.03Å
370T94.2Very high92.7Very high1 Ų144.8 Ų44.81%0.00623%0.234CC..Hα-helixtrans-63.1-43176.2-58.40000111.6Y366 V367 Q368 H374 F402 I403 V452Y366-T370 PolarHBondContact O-N 2.88Å; Y366-T370 VanDerWaalsContact O-N 3.12Å; Y366-T370 PolarHBondContact O-OG1 3.22Å; V367-T370 PolarHBondContact O-N 3.32Å; Q368-T370 VanDerWaalsContact C-N 3.28Å; Q368-T370 PolarHBondContact O-N 3.22Å; T370-H374 PolarHBondContact O-N 3.43Å; T370-H374 VanDerWaalsContact O-N 3.14Å; T370-F402 HydrophobicContact CG2-CE2 4.08Å; T370-F402 HydrophobicContact CG2-CZ 4.35Å; T370-I403 HydrophobicContact CG2-CD1 3.63Å; T370-I403 HydrophobicContact CG2-CG1 3.67Å; T370-V452 HydrophobicContact CG2-CG1 4.04Å; T370-V452 HydrophobicContact CG2-CG2 4.05Å
371L94.4Very high93.4Very high4 Ų443.1 Ų43.12%0.02123%0.226CC..Hα-helixtrans-65.4-40.2178.1-78.3170.4000112.6V367 Q368 H374 K375 Q448 V452V367-L371 HydrophobicContact CG1-CD1 3.88Å; V367-L371 HydrophobicContact CG1-CG 4.36Å; V367-L371 WeakPolarHBondContact O-CB 3.4Å; V367-L371 WeakPolarHBondContact O-CG 3.34Å; V367-L371 PolarHBondContact O-N 3.5Å; Q368-L371 WeakPolarHBondContact O-CB 3.4Å; Q368-L371 PolarHBondContact O-N 2.89Å; Q368-L371 VanDerWaalsContact O-N 3.11Å; L371-H374 PolarHBondContact O-N 3.45Å; L371-K375 WeakPolarHBondContact O-CB 3.31Å; L371-K375 VanDerWaalsContact O-CG 3.3Å; L371-K375 WeakPolarHBondContact O-CG 3.29Å; L371-K375 PolarHBondContact O-N 2.9Å; L371-Q448 HydrophobicContact CD1-CB 3.87Å; L371-Q448 HydrophobicContact CD2-CB 3.98Å; L371-Q448 WeakPolarHBondContact CD2-O 3.32Å; L371-V452 HydrophobicContact CD2-CG2 3.56Å; L371-V452 HydrophobicContact CG-CG2 3.73Å
372D95.1Very high93.9Very high80 Ų8041 Ų4143%0.42821%0.212SC..Hα-helixtrans-65.5-42.3-178.6-66-20.9000111Q368 T369 K375 K376Q368-D372 PolarHBondContact NE2-OD1 3.33Å; Q368-D372 PolarHBondContact O-N 3.38Å; T369-D372 PolarHBondContact O-N 3.27Å; D372-K375 PolarHBondContact O-N 3.41Å; D372-K376 WeakPolarHBondContact O-CB 3.31Å; D372-K376 PolarHBondContact O-N 2.91Å
373V95.5Very high94.1Very high15 Ų1541.3 Ų41.39%0.09122%0.221CC..Hα-helixtrans-59.5-49.8172.61740000110.5A351 T369 K375 K376 Y377 F402A351-V373 HydrophobicContact CB-CG2 3.72Å; T369-V373 WeakPolarHBondContact O-CG2 3.45Å; T369-V373 PolarHBondContact O-N 3.03Å; V373-K375 PolarHBondContact O-N 2.88Å; V373-K376 PolarHBondContact O-N 3.46Å; V373-Y377 HydrophobicContact CG1-CD2 3.97Å; V373-Y377 HydrophobicContact CG1-CE2 4.03Å; V373-Y377 VanDerWaalsContact O-CD2 3.24Å; V373-Y377 WeakPolarHBondContact O-CD2 3.34Å; V373-Y377 PolarHBondContact O-N 3.37Å; V373-F402 HydrophobicContact CB-CZ 4.44Å; V373-F402 HydrophobicContact CG1-CE1 4.19Å; V373-F402 HydrophobicContact CG1-CZ 4Å
374H95.8Very high94.3Very high24 Ų2440.6 Ų40.611%0.11122%0.216CC..Hα-helixtrans-59.8-46.4178.2174.2-80.6000111.9T370 L371 K376 Y377 N378 Y455T370-H374 PolarHBondContact O-N 3.43Å; T370-H374 VanDerWaalsContact O-N 3.14Å; L371-H374 PolarHBondContact O-N 3.45Å; H374-K376 PolarHBondContact O-N 2.88Å; H374-Y377 PolarHBondContact O-N 3.03Å; H374-N378 WeakPolarHBondContact O-CB 3.5Å; H374-N378 PolarHBondContact O-N 2.86Å; H374-Y455 AromaticContact CD2-CE2 3.69Å; H374-Y455 AromaticContact NE2-CE2 3.97Å; H374-Y455 PolarHBondContact NE2-OH 3.19Å
375K95.3Very high94.4Very high89 Ų8934.6 Ų34.639%0.38719%0.19SC..Hα-helixtrans-61.2-44.2-179.8-76.4176.4-175.6175.50111.9L371 D372 V373 A379L371-K375 WeakPolarHBondContact O-CB 3.31Å; L371-K375 VanDerWaalsContact O-CG 3.3Å; L371-K375 WeakPolarHBondContact O-CG 3.29Å; L371-K375 PolarHBondContact O-N 2.9Å; D372-K375 PolarHBondContact O-N 3.41Å; V373-K375 PolarHBondContact O-N 2.88Å; K375-A379 WeakPolarHBondContact O-CB 3.41Å; K375-A379 PolarHBondContact O-N 2.82Å
376K95.2Very high94.4Very high89 Ų8937.2 Ų37.239%0.38720%0.203SC..Hα-helixtrans-55.7-54177.9179.9-177.6177.1-178.20111.2D314 D372 V373 H374 A379 L380D314-K376 WeakPolarHBondContact OD1-CE 3.46Å; D314-K376 IonicContact OD1-NZ 2.81Å; D314-K376 PolarHBondContact OD1-NZ 3Å; D314-K376 IonicContact OD2-NZ 3.11Å; D314-K376 PolarHBondContact OD2-NZ 3.38Å; D372-K376 WeakPolarHBondContact O-CB 3.31Å; D372-K376 PolarHBondContact O-N 2.91Å; V373-K376 PolarHBondContact O-N 3.46Å; H374-K376 PolarHBondContact O-N 2.88Å; K376-A379 PolarHBondContact O-N 3.24Å; K376-L380 PolarHBondContact O-N 3.24Å; K376-L380 VanDerWaalsContact O-N 3.16Å
377Y95.6Very high94.4Very high4 Ų441.6 Ų41.62%0.01623%0.226CC..Hα-helixtrans-79-28.1-175.4-67.3-68.7000113.5H343 I344 Q347 V373 H374 A379 L380 V381H343-Y377 AromaticContact CD2-CE1 3.66Å; H343-Y377 AromaticContact CD2-CZ 3.79Å; H343-Y377 PolarHBondContact CD2-OH 2.92Å; H343-Y377 AromaticContact NE2-CE1 3.63Å; H343-Y377 AromaticContact NE2-CZ 3.61Å; H343-Y377 PolarHBondContact NE2-OH 3.32Å; I344-Y377 HydrophobicContact CB-CD2 4.39Å; I344-Y377 HydrophobicContact CD1-CD1 4.14Å; I344-Y377 HydrophobicContact CD1-CG 3.92Å; I344-Y377 HydrophobicContact CG1-CD1 3.69Å; I344-Y377 HydrophobicContact CG1-CD2 3.88Å; I344-Y377 HydrophobicContact CG1-CE1 4.06Å; I344-Y377 HydrophobicContact CG1-CE2 4.24Å; I344-Y377 HydrophobicContact CG1-CG 3.6Å; I344-Y377 HydrophobicContact CG2-CD2 4.02Å; I344-Y377 HydrophobicContact CG2-CE2 4.5Å; I344-Y377 HydrophobicContact CG2-CG 4.44Å; Q347-Y377 HydrophobicContact CB-CE2 4.15Å; Q347-Y377 WeakPolarHBondContact CB-OH 3.36Å; Q347-Y377 VanDerWaalsContact CG-OH 3.26Å; Q347-Y377 WeakPolarHBondContact CG-OH 3.48Å; V373-Y377 HydrophobicContact CG1-CD2 3.97Å; V373-Y377 HydrophobicContact CG1-CE2 4.03Å; V373-Y377 VanDerWaalsContact O-CD2 3.24Å; V373-Y377 WeakPolarHBondContact O-CD2 3.34Å; V373-Y377 PolarHBondContact O-N 3.37Å; H374-Y377 PolarHBondContact O-N 3.03Å; Y377-A379 VanDerWaalsContact C-N 3.35Å; Y377-L380 HydrophobicContact CD1-CD2 4.07Å; Y377-L380 WeakPolarHBondContact O-CB 3.32Å; Y377-L380 PolarHBondContact O-N 3.48Å; Y377-V381 VanDerWaalsContact O-CG2 3.3Å; Y377-V381 WeakPolarHBondContact O-CG2 3.45Å; Y377-V381 PolarHBondContact O-N 2.83Å
378N94.7Very high94.4Very high58 Ų5843.3 Ų43.331%0.3124%0.235SC..Hα-helixtrans-62.8-44169.8-172.130.2000110.9H374 L380 V381 M382 L395H374-N378 WeakPolarHBondContact O-CB 3.5Å; H374-N378 PolarHBondContact O-N 2.86Å; N378-L380 VanDerWaalsContact C-N 3.33Å; N378-L380 PolarHBondContact O-N 3.46Å; N378-V381 PolarHBondContact O-N 3.22Å; N378-M382 VanDerWaalsContact O-CG 3.32Å; N378-M382 WeakPolarHBondContact O-CG 3.45Å; N378-M382 PolarHBondContact O-N 3.27Å; N378-L395 HydrophobicContact CB-CD2 3.96Å
379A95.3Very high94.5Very high58 Ų5844.2 Ų44.248%0.47925%0.253SS..Hα-helixtrans-59.4-44.1174.800000111.6K375 K376 Y377 V381 M382 S383K375-A379 WeakPolarHBondContact O-CB 3.41Å; K375-A379 PolarHBondContact O-N 2.82Å; K376-A379 PolarHBondContact O-N 3.24Å; Y377-A379 VanDerWaalsContact C-N 3.35Å; A379-V381 PolarHBondContact O-N 2.87Å; A379-M382 PolarHBondContact O-N 3.02Å; A379-S383 WeakPolarHBondContact O-CB 3.48Å; A379-S383 PolarHBondContact O-N 3.31Å; A379-S383 PolarHBondContact O-OG 3.47Å; A379-S383 VanDerWaalsContact O-OG 3.04Å
380L94.6Very high94.5Very high7 Ų744 Ų444%0.03726%0.256CS..Hα-helixtrans-56.8-48.3174.1174.465.8000112L311 N316 L319 L340 K376 Y377 N378 M382 S383 A384 F385L311-L380 HydrophobicContact CD2-CD2 3.99Å; N316-L380 HydrophobicContact CB-CD1 4.07Å; N316-L380 WeakPolarHBondContact OD1-CD1 3.32Å; L319-L380 HydrophobicContact CD1-CD1 3.87Å; L319-L380 HydrophobicContact CD1-CD2 4.28Å; L340-L380 HydrophobicContact CD1-CD2 4.11Å; K376-L380 PolarHBondContact O-N 3.24Å; K376-L380 VanDerWaalsContact O-N 3.16Å; Y377-L380 HydrophobicContact CD1-CD2 4.07Å; Y377-L380 WeakPolarHBondContact O-CB 3.32Å; Y377-L380 PolarHBondContact O-N 3.48Å; N378-L380 VanDerWaalsContact C-N 3.33Å; N378-L380 PolarHBondContact O-N 3.46Å; L380-M382 VanDerWaalsContact C-N 3.34Å; L380-M382 PolarHBondContact O-N 2.86Å; L380-S383 PolarHBondContact O-N 3.4Å; L380-A384 HydrophobicContact CD1-CB 3.64Å; L380-A384 WeakPolarHBondContact O-CB 3.15Å; L380-A384 PolarHBondContact O-N 3.31Å; L380-F385 HydrophobicContact CD1-CE2 4.41Å; L380-F385 HydrophobicContact CD1-CZ 4.34Å; L380-F385 HydrophobicContact CD2-CE2 4.03Å; L380-F385 HydrophobicContact CD2-CZ 4.34Å; L380-F385 HydrophobicContact CG-CE2 3.86Å; L380-F385 HydrophobicContact CG-CZ 4.24Å
381V95.6Very high94.6Very high0 Ų044 Ų440%026%0.256CS..Hα-helixtrans-64.5-39180175.30000111.5L340 Y377 N378 A379 F385 N387 F391 V392 L395L340-V381 HydrophobicContact CD2-CG2 4.05Å; Y377-V381 VanDerWaalsContact O-CG2 3.3Å; Y377-V381 WeakPolarHBondContact O-CG2 3.45Å; Y377-V381 PolarHBondContact O-N 2.83Å; N378-V381 PolarHBondContact O-N 3.22Å; A379-V381 PolarHBondContact O-N 2.87Å; V381-F385 HydrophobicContact CB-CD2 4.43Å; V381-F385 HydrophobicContact CG2-CD2 4.08Å; V381-F385 CarbonylContact O-C 3.58Å; V381-F385 PolarHBondContact O-N 3.12Å; V381-N387 PolarHBondContact O-N 3.34Å; V381-N387 VanDerWaalsContact O-N 3.15Å; V381-F391 HydrophobicContact CG1-CB 4.04Å; V381-F391 HydrophobicContact CG2-CB 4.4Å; V381-V392 HydrophobicContact CG1-CG2 3.66Å; V381-L395 HydrophobicContact CG2-CB 4.49Å; V381-L395 HydrophobicContact CG2-CD2 4.41Å
382M94Very high94.7Very high76 Ų7645.6 Ų45.637%0.37427%0.266SS..Hα-helixtrans-66.9-44.2176.7-67.9-54.598.400112.3N378 A379 L380 N387 V392N378-M382 VanDerWaalsContact O-CG 3.32Å; N378-M382 WeakPolarHBondContact O-CG 3.45Å; N378-M382 PolarHBondContact O-N 3.27Å; A379-M382 PolarHBondContact O-N 3.02Å; L380-M382 VanDerWaalsContact C-N 3.34Å; L380-M382 PolarHBondContact O-N 2.86Å; M382-N387 HydrophobicContact CE-CB 3.88Å; M382-N387 WeakPolarHBondContact CE-OD1 3.49Å; M382-N387 HydrophobicContact SD-CB 3.95Å; M382-V392 HydrophobicContact CE-CG2 4.11Å
383S92.9Very high94.7Very high79 Ų7944.3 Ų44.355%0.55227%0.266SS*.Hα-helixtrans-88-45.1-171.868.10000113.9A379 L380A379-S383 WeakPolarHBondContact O-CB 3.48Å; A379-S383 PolarHBondContact O-N 3.31Å; A379-S383 PolarHBondContact O-OG 3.47Å; A379-S383 VanDerWaalsContact O-OG 3.04Å; L380-S383 PolarHBondContact O-N 3.4Å
384A93.4Very high94.8Very high7 Ų743.8 Ų43.86%0.05826%0.264CS..Hα-helixtrans-91.6-30.4-172.800000112.6G320 L380G320-A384 VanDerWaalsContact CA-O 3.26Å; G320-A384 WeakPolarHBondContact CA-O 3.35Å; L380-A384 HydrophobicContact CD1-CB 3.64Å; L380-A384 WeakPolarHBondContact O-CB 3.15Å; L380-A384 PolarHBondContact O-N 3.31Å
385F94.8Very high94.8Very high0 Ų042.8 Ų42.80%026%0.259CS..SBendtrans-111.318.6-174.6-49.9-38.5000113.3F307 L319 Y323 L340 L380 V381 N387 D388 F391F307-F385 HydrophobicContact CE2-CE1 4.16Å; F307-F385 AromaticContact CE2-CZ 3.98Å; F307-F385 HydrophobicContact CE2-CZ 3.98Å; F307-F385 HydrophobicContact CZ-CE1 4.43Å; F307-F385 AromaticContact CZ-CZ 3.89Å; F307-F385 HydrophobicContact CZ-CZ 3.89Å; L319-F385 HydrophobicContact CB-CE1 4.07Å; L319-F385 HydrophobicContact CB-CZ 4.23Å; Y323-F385 HydrophobicContact CD2-CB 4.16Å; Y323-F385 AromaticContact CD2-CD1 3.99Å; Y323-F385 HydrophobicContact CD2-CD1 3.99Å; Y323-F385 HydrophobicContact CD2-CG 4.42Å; Y323-F385 HydrophobicContact CE2-CB 4.3Å; Y323-F385 HydrophobicContact CG-CB 4.41Å; Y323-F385 AromaticContact CG-CD1 3.84Å; Y323-F385 HydrophobicContact CG-CD1 3.84Å; L340-F385 HydrophobicContact CD1-CE2 4.3Å; L340-F385 HydrophobicContact CD2-CD2 4.31Å; L340-F385 HydrophobicContact CD2-CE2 3.89Å; L380-F385 HydrophobicContact CD1-CE2 4.41Å; L380-F385 HydrophobicContact CD1-CZ 4.34Å; L380-F385 HydrophobicContact CD2-CE2 4.03Å; L380-F385 HydrophobicContact CD2-CZ 4.34Å; L380-F385 HydrophobicContact CG-CE2 3.86Å; L380-F385 HydrophobicContact CG-CZ 4.24Å; V381-F385 HydrophobicContact CB-CD2 4.43Å; V381-F385 HydrophobicContact CG2-CD2 4.08Å; V381-F385 CarbonylContact O-C 3.58Å; V381-F385 PolarHBondContact O-N 3.12Å; F385-N387 PolarHBondContact O-N 2.7Å; F385-D388 VanDerWaalsContact O-CB 3.32Å; F385-D388 WeakPolarHBondContact O-CB 3.15Å; F385-D388 PolarHBondContact O-N 3.34Å; F385-F391 HydrophobicContact CB-CB 4.33Å; F385-F391 HydrophobicContact CB-CD2 4.12Å; F385-F391 HydrophobicContact CB-CG 4.17Å; F385-F391 HydrophobicContact CD2-CB 4.16Å; F385-F391 AromaticContact CD2-CD1 3.75Å; F385-F391 HydrophobicContact CD2-CD1 3.75Å; F385-F391 HydrophobicContact CD2-CE1 4.19Å; F385-F391 AromaticContact CD2-CG 3.9Å; F385-F391 HydrophobicContact CD2-CG 3.9Å; F385-F391 HydrophobicContact CE2-CD1 4.03Å; F385-F391 HydrophobicContact CE2-CE1 4.21Å; F385-F391 HydrophobicContact CG-CD1 4.26Å; F385-F391 HydrophobicContact CG-CD2 4.32Å; F385-F391 HydrophobicContact CG-CE1 4.49Å; F385-F391 HydrophobicContact CG-CG 4.14Å; F385-F391 HydrophobicContact CZ-CE1 4.48Å
386N92.3Very high94.8Very high103 Ų10340.7 Ų40.755%0.55125%0.252SS*.THydrogen-bonded Turntrans5033.5175.5-65-23.5000114.8Y323 D388Y323-N386 HydrophobicContact CE1-CB 4.17Å; N386-D388 VanDerWaalsContact C-N 3.26Å; N386-D388 PolarHBondContact O-N 3.03Å
387N93.4Very high94.8Very high93 Ų9342 Ų4250%0.49726%0.258SS..THydrogen-bonded Turntrans56.537.7-175.6-171.530.3000113.3V381 M382 F385 A389 V392V381-N387 PolarHBondContact O-N 3.34Å; V381-N387 VanDerWaalsContact O-N 3.15Å; M382-N387 HydrophobicContact CE-CB 3.88Å; M382-N387 WeakPolarHBondContact CE-OD1 3.49Å; M382-N387 HydrophobicContact SD-CB 3.95Å; F385-N387 PolarHBondContact O-N 2.7Å; N387-A389 PolarHBondContact O-N 3.14Å; N387-V392 WeakPolarHBondContact OD1-CG2 3.4Å
388D94.4Very high94.8Very high36 Ų3641.8 Ų41.819%0.19326%0.257CS..  trans-59.9126.6174.7179.7-94.1000111.5Y323 K337 F385 N386 G390 F391 V392Y323-D388 HydrophobicContact CE2-CB 4.1Å; K337-D388 WeakPolarHBondContact CE-OD1 3.39Å; K337-D388 IonicContact NZ-OD1 3.91Å; K337-D388 PolarHBondContact NZ-OD1 3.3Å; K337-D388 VanDerWaalsContact NZ-OD1 3.1Å; F385-D388 VanDerWaalsContact O-CB 3.32Å; F385-D388 WeakPolarHBondContact O-CB 3.15Å; F385-D388 PolarHBondContact O-N 3.34Å; N386-D388 VanDerWaalsContact C-N 3.26Å; N386-D388 PolarHBondContact O-N 3.03Å; D388-G390 PolarHBondContact O-N 2.87Å; D388-G390 VanDerWaalsContact O-N 3.14Å; D388-G390 VanDerWaalsContact OD1-CA 3.32Å; D388-G390 WeakPolarHBondContact OD1-CA 3.46Å; D388-G390 PolarHBondContact OD1-N 2.92Å; D388-F391 HydrophobicContact CB-CB 4.38Å; D388-F391 HydrophobicContact CB-CD2 3.86Å; D388-F391 PolarHBondContact O-N 3.39Å; D388-F391 VanDerWaalsContact O-N 3.08Å; D388-F391 WeakPolarHBondContact OD1-CD2 3.49Å; D388-F391 PolarHBondContact OD1-N 3.3Å; D388-F391 VanDerWaalsContact OD1-N 3.15Å; D388-V392 WeakPolarHBondContact O-CG2 3.19Å; D388-V392 PolarHBondContact O-N 3.43Å
389A94.3Very high94.8Very high80 Ų8039 Ų3966%0.66124%0.242SC*.Hα-helixtrans-58.8-31.3-176.300000113.3N387 A393N387-A389 PolarHBondContact O-N 3.14Å; A389-A393 WeakPolarHBondContact O-CB 3.45Å; A389-A393 PolarHBondContact O-N 2.93Å
390G94.4Very high94.7Very high21 Ų2137.2 Ų37.222%0.21623%0.229CC..Hα-helixtrans-74-36.217800000113D388 A393 A394D388-G390 PolarHBondContact O-N 2.87Å; D388-G390 VanDerWaalsContact O-N 3.14Å; D388-G390 VanDerWaalsContact OD1-CA 3.32Å; D388-G390 WeakPolarHBondContact OD1-CA 3.46Å; D388-G390 PolarHBondContact OD1-N 2.92Å; G390-A393 PolarHBondContact O-N 3.38Å; G390-A394 PolarHBondContact O-N 3.48Å
391F96Very high94.6Very high0 Ų043.1 Ų43.10%025%0.251CS..Hα-helixtrans-72.2-35.8172.8-77.3-80.1000112.2F307 Y323 L333 L336 K337 L340 V381 F385 D388 A393 A394 L395F307-F391 HydrophobicContact CZ-CE1 4.29Å; Y323-F391 HydrophobicContact CD2-CD2 4.24Å; Y323-F391 AromaticContact CD2-CE2 3.61Å; Y323-F391 HydrophobicContact CD2-CE2 3.61Å; Y323-F391 HydrophobicContact CD2-CZ 4.25Å; Y323-F391 HydrophobicContact CE2-CD2 4.06Å; Y323-F391 AromaticContact CE2-CE2 3.74Å; Y323-F391 HydrophobicContact CE2-CE2 3.74Å; L333-F391 HydrophobicContact CD1-CE2 4.48Å; L333-F391 HydrophobicContact CD2-CE2 4.23Å; L336-F391 HydrophobicContact CB-CE1 4.2Å; L336-F391 HydrophobicContact CB-CZ 3.82Å; K337-F391 HydrophobicContact CG-CD1 3.94Å; K337-F391 HydrophobicContact CG-CD2 3.97Å; K337-F391 HydrophobicContact CG-CE1 3.91Å; K337-F391 HydrophobicContact CG-CE2 3.9Å; K337-F391 HydrophobicContact CG-CG 4.02Å; K337-F391 HydrophobicContact CG-CZ 3.9Å; L340-F391 HydrophobicContact CB-CD1 4.35Å; L340-F391 HydrophobicContact CB-CE1 4.4Å; L340-F391 HydrophobicContact CD2-CB 4.49Å; L340-F391 HydrophobicContact CD2-CD1 3.56Å; L340-F391 HydrophobicContact CD2-CE1 4.3Å; V381-F391 HydrophobicContact CG1-CB 4.04Å; V381-F391 HydrophobicContact CG2-CB 4.4Å; F385-F391 HydrophobicContact CB-CB 4.33Å; F385-F391 HydrophobicContact CB-CD2 4.12Å; F385-F391 HydrophobicContact CB-CG 4.17Å; F385-F391 HydrophobicContact CD2-CB 4.16Å; F385-F391 AromaticContact CD2-CD1 3.75Å; F385-F391 HydrophobicContact CD2-CD1 3.75Å; F385-F391 HydrophobicContact CD2-CE1 4.19Å; F385-F391 AromaticContact CD2-CG 3.9Å; F385-F391 HydrophobicContact CD2-CG 3.9Å; F385-F391 HydrophobicContact CE2-CD1 4.03Å; F385-F391 HydrophobicContact CE2-CE1 4.21Å; F385-F391 HydrophobicContact CG-CD1 4.26Å; F385-F391 HydrophobicContact CG-CD2 4.32Å; F385-F391 HydrophobicContact CG-CE1 4.49Å; F385-F391 HydrophobicContact CG-CG 4.14Å; F385-F391 HydrophobicContact CZ-CE1 4.48Å; D388-F391 HydrophobicContact CB-CB 4.38Å; D388-F391 HydrophobicContact CB-CD2 3.86Å; D388-F391 PolarHBondContact O-N 3.39Å; D388-F391 VanDerWaalsContact O-N 3.08Å; D388-F391 WeakPolarHBondContact OD1-CD2 3.49Å; D388-F391 PolarHBondContact OD1-N 3.3Å; D388-F391 VanDerWaalsContact OD1-N 3.15Å; F391-A393 VanDerWaalsContact C-N 3.34Å; F391-A394 WeakPolarHBondContact O-CB 3.45Å; F391-A394 PolarHBondContact O-N 2.94Å; F391-L395 PolarHBondContact O-N 3.44Å
392V96.4Very high94.5Very high38 Ų3843.1 Ų43.123%0.2325%0.251CS..Hα-helixtrans-60.7-44.2169.7175.20000110.8V381 M382 N387 D388 A394 L395 D396V381-V392 HydrophobicContact CG1-CG2 3.66Å; M382-V392 HydrophobicContact CE-CG2 4.11Å; N387-V392 WeakPolarHBondContact OD1-CG2 3.4Å; D388-V392 WeakPolarHBondContact O-CG2 3.19Å; D388-V392 PolarHBondContact O-N 3.43Å; V392-A394 VanDerWaalsContact C-N 3.33Å; V392-A394 PolarHBondContact O-N 3.07Å; V392-L395 PolarHBondContact O-N 2.9Å; V392-D396 WeakPolarHBondContact O-CB 3.29Å; V392-D396 PolarHBondContact O-N 3.33Å
393A95.9Very high94.5Very high53 Ų5339.6 Ų39.644%0.43823%0.233SC..Hα-helixtrans-63.3-37.8175.800000112.6A389 G390 F391 D396 K397A389-A393 WeakPolarHBondContact O-CB 3.45Å; A389-A393 PolarHBondContact O-N 2.93Å; G390-A393 PolarHBondContact O-N 3.38Å; F391-A393 VanDerWaalsContact C-N 3.34Å; A393-D396 PolarHBondContact O-N 2.95Å; A393-K397 VanDerWaalsContact O-CB 3.27Å; A393-K397 WeakPolarHBondContact O-CB 3.15Å; A393-K397 PolarHBondContact O-N 3.27Å
394A96.3Very high94.3Very high5 Ų536.5 Ų36.54%0.04121%0.211CC..Hα-helixtrans-63.9-4517500000111.9K337 E341 G390 F391 V392 K397 A398K337-A394 HydrophobicContact CB-CB 4.43Å; K337-A394 WeakPolarHBondContact O-CB 3.35Å; E341-A394 HydrophobicContact CB-CB 4.18Å; G390-A394 PolarHBondContact O-N 3.48Å; F391-A394 WeakPolarHBondContact O-CB 3.45Å; F391-A394 PolarHBondContact O-N 2.94Å; V392-A394 VanDerWaalsContact C-N 3.33Å; V392-A394 PolarHBondContact O-N 3.07Å; A394-K397 PolarHBondContact O-N 3.25Å; A394-A398 WeakPolarHBondContact O-CB 3.36Å; A394-A398 PolarHBondContact O-N 3.15Å
395L96.4Very high94.1Very high2 Ų240.6 Ų40.61%0.0123%0.232CC..Hα-helixtrans-58.9-49.3172.8169.764.8000111.5I344 N378 V381 F391 V392 K397 A398 C399I344-L395 HydrophobicContact CD1-CB 4.24Å; I344-L395 HydrophobicContact CD1-CD1 3.78Å; I344-L395 HydrophobicContact CG2-CD1 4.27Å; N378-L395 HydrophobicContact CB-CD2 3.96Å; V381-L395 HydrophobicContact CG2-CB 4.49Å; V381-L395 HydrophobicContact CG2-CD2 4.41Å; F391-L395 PolarHBondContact O-N 3.44Å; V392-L395 PolarHBondContact O-N 2.9Å; L395-K397 VanDerWaalsContact C-N 3.32Å; L395-K397 PolarHBondContact O-N 2.91Å; L395-A398 PolarHBondContact O-N 3.45Å; L395-C399 WeakPolarHBondContact O-CB 3.35Å; L395-C399 PolarHBondContact O-N 3.41Å; L395-C399 PolarHBondContact O-SG 3.33Å
396D94.9Very high93.7Very high45 Ų4540.6 Ų40.624%0.24123%0.232CC..Hα-helixtrans-59.7-43.4-179.7-89.5-13.5000111.4V392 A393 G400 K454 Y455V392-D396 WeakPolarHBondContact O-CB 3.29Å; V392-D396 PolarHBondContact O-N 3.33Å; A393-D396 PolarHBondContact O-N 2.95Å; D396-G400 PolarHBondContact O-N 2.97Å; D396-K454 IonicContact OD1-NZ 3.39Å; D396-K454 PolarHBondContact OD1-NZ 3.43Å; D396-K454 IonicContact OD2-NZ 2.7Å; D396-K454 PolarHBondContact OD2-NZ 2.96Å; D396-Y455 HydrophobicContact CB-CE1 4.05Å; D396-Y455 WeakPolarHBondContact OD1-CE1 3.47Å; D396-Y455 VanDerWaalsContact OD1-CZ 3.27Å; D396-Y455 PolarHBondContact OD1-OH 3.3Å
397K94.7Very high93.3Very high117 Ų11736.3 Ų36.351%0.50921%0.211SC..Hα-helixtrans-67.9-41.6178.5-173172.4165.3-141.70111.8E341 A393 A394 L395 G400 R401E341-K397 VanDerWaalsContact CD-NZ 3.33Å; E341-K397 WeakPolarHBondContact OE1-CD 3.33Å; E341-K397 WeakPolarHBondContact OE1-CE 3.26Å; E341-K397 IonicContact OE1-NZ 3.83Å; E341-K397 PolarHBondContact OE1-NZ 3.45Å; E341-K397 VanDerWaalsContact OE1-NZ 3.07Å; E341-K397 WeakPolarHBondContact OE2-CD 3.4Å; E341-K397 WeakPolarHBondContact OE2-CE 3.24Å; E341-K397 IonicContact OE2-NZ 3.97Å; E341-K397 PolarHBondContact OE2-NZ 3.08Å; A393-K397 VanDerWaalsContact O-CB 3.27Å; A393-K397 WeakPolarHBondContact O-CB 3.15Å; A393-K397 PolarHBondContact O-N 3.27Å; A394-K397 PolarHBondContact O-N 3.25Å; L395-K397 VanDerWaalsContact C-N 3.32Å; L395-K397 PolarHBondContact O-N 2.91Å; K397-G400 PolarHBondContact O-N 2.98Å; K397-R401 WeakPolarHBondContact O-CG 3.4Å; K397-R401 PolarHBondContact O-N 3.21Å
398A96.1Very high92.8Very high0 Ų032 Ų320%019%0.187CC..Hα-helixtrans-62.2-47.1175.700000111.7E341 I344 H345 A394 L395 G400 R401 F402E341-A398 HydrophobicContact CG-CB 4.09Å; E341-A398 WeakPolarHBondContact O-CB 3.46Å; I344-A398 HydrophobicContact CB-CB 3.69Å; I344-A398 HydrophobicContact CG2-CB 3.58Å; H345-A398 HydrophobicContact CB-CB 4.48Å; A394-A398 WeakPolarHBondContact O-CB 3.36Å; A394-A398 PolarHBondContact O-N 3.15Å; L395-A398 PolarHBondContact O-N 3.45Å; A398-G400 PolarHBondContact O-N 3.1Å; A398-R401 PolarHBondContact O-N 3.39Å; A398-F402 WeakPolarHBondContact O-CD1 3.41Å; A398-F402 PolarHBondContact O-N 3.25Å
399C95.3Very high92.3Very high0 Ų030.6 Ų30.60%018%0.18CC..Hα-helixtrans-58.7-47.2175.5-67.70000111.8L395 R401 F402 I403 Y455L395-C399 WeakPolarHBondContact O-CB 3.35Å; L395-C399 PolarHBondContact O-N 3.41Å; L395-C399 PolarHBondContact O-SG 3.33Å; C399-R401 PolarHBondContact O-N 3.36Å; C399-F402 VanDerWaalsContact CA-CE1 3.46Å; C399-F402 HydrophobicContact CB-CE1 4.12Å; C399-F402 PolarHBondContact O-N 2.54Å; C399-I403 HydrophobicContact CB-CD1 4.2Å; C399-I403 VanDerWaalsContact O-CB 3.26Å; C399-I403 WeakPolarHBondContact O-CB 3.45Å; C399-I403 WeakPolarHBondContact O-CD1 3.32Å; C399-I403 WeakPolarHBondContact O-CG1 3.41Å; C399-I403 PolarHBondContact O-N 2.95Å; C399-Y455 HydrophobicContact CB-CD1 3.76Å; C399-Y455 HydrophobicContact CB-CD2 3.96Å; C399-Y455 HydrophobicContact CB-CE1 3.81Å; C399-Y455 HydrophobicContact CB-CE2 3.99Å; C399-Y455 HydrophobicContact CB-CG 3.86Å
400G92.9Very high91.8Very high19 Ų1933.4 Ų33.420%0.19617%0.174CC..Hα-helixtrans-56.1-36.6173.100000113.1D396 K397 A398 N404D396-G400 PolarHBondContact O-N 2.97Å; K397-G400 PolarHBondContact O-N 2.98Å; A398-G400 PolarHBondContact O-N 3.1Å; G400-N404 PolarHBondContact O-ND2 3.01Å
401R92.7Very high91.1Very high132 Ų13236.9 Ų36.950%0.49819%0.185SC..Hα-helixtrans-74.5-50.1180-70.6179.381.7-177.30.9113.1E341 K397 A398 C399 N405E341-R401 IonicContact OE1-NH1 2.86Å; E341-R401 PolarHBondContact OE1-NH1 3.25Å; K397-R401 WeakPolarHBondContact O-CG 3.4Å; K397-R401 PolarHBondContact O-N 3.21Å; A398-R401 PolarHBondContact O-N 3.39Å; C399-R401 PolarHBondContact O-N 3.36Å; R401-N405 PolarHBondContact O-N 3.19Å; R401-N405 VanDerWaalsContact O-N 3.12Å
402F93.8Very high90.3Very high0 Ų038.8 Ų38.80%020%0.201CC..Hα-helixtrans-77.2-28.8-174.682-104.7000113I344 L349 I352 T370 V373 A398 C399 N404 N405 N406I344-F402 HydrophobicContact CG2-CE1 4.48Å; L349-F402 HydrophobicContact CD2-CB 4.27Å; L349-F402 HydrophobicContact CG-CB 4.3Å; I352-F402 HydrophobicContact CD1-CD2 3.9Å; I352-F402 HydrophobicContact CD1-CE2 4.16Å; T370-F402 HydrophobicContact CG2-CE2 4.08Å; T370-F402 HydrophobicContact CG2-CZ 4.35Å; V373-F402 HydrophobicContact CB-CZ 4.44Å; V373-F402 HydrophobicContact CG1-CE1 4.19Å; V373-F402 HydrophobicContact CG1-CZ 4Å; A398-F402 WeakPolarHBondContact O-CD1 3.41Å; A398-F402 PolarHBondContact O-N 3.25Å; C399-F402 VanDerWaalsContact CA-CE1 3.46Å; C399-F402 HydrophobicContact CB-CE1 4.12Å; C399-F402 PolarHBondContact O-N 2.54Å; F402-N404 VanDerWaalsContact C-N 3.34Å; F402-N404 PolarHBondContact O-N 2.91Å; F402-N405 CarbonylContact O-C 3.43Å; F402-N405 VanDerWaalsContact O-O 3.12Å; F402-N406 WeakPolarHBondContact O-CB 2.98Å; F402-N406 PolarHBondContact O-ND2 3.36Å
403I92.6Very high89.4Confident2 Ų245.8 Ų45.81%0.0123%0.231CC..Hα-helixtrans-68.6-36.6178.8-68.4170.9000111.2Y366 T370 C399 N406 S418 V452 Y455 I456Y366-I403 PolarHBondContact OH-O 2.95Å; T370-I403 HydrophobicContact CG2-CD1 3.63Å; T370-I403 HydrophobicContact CG2-CG1 3.67Å; C399-I403 HydrophobicContact CB-CD1 4.2Å; C399-I403 VanDerWaalsContact O-CB 3.26Å; C399-I403 WeakPolarHBondContact O-CB 3.45Å; C399-I403 WeakPolarHBondContact O-CD1 3.32Å; C399-I403 WeakPolarHBondContact O-CG1 3.41Å; C399-I403 PolarHBondContact O-N 2.95Å; I403-N406 PolarHBondContact O-ND2 3.34Å; I403-S418 WeakPolarHBondContact O-CB 3.34Å; I403-S418 PolarHBondContact O-OG 3.18Å; I403-V452 HydrophobicContact CD1-CG1 4.4Å; I403-V452 HydrophobicContact CG2-CG1 4.49Å; I403-Y455 HydrophobicContact CD1-CD2 3.79Å; I403-Y455 HydrophobicContact CD1-CG 3.95Å; I403-I456 HydrophobicContact CG2-CD1 3.69Å
404N90.3Very high88.6Confident14 Ų1444.9 Ų44.98%0.07522%0.221CC..Hα-helixtrans-90.3-14-179.4-62.7-69.3000113.4G400 F402 Y455 E457G400-N404 PolarHBondContact O-ND2 3.01Å; F402-N404 VanDerWaalsContact C-N 3.34Å; F402-N404 PolarHBondContact O-N 2.91Å; N404-Y455 PolarHBondContact ND2-O 3.4Å; N404-E457 PolarHBondContact OD1-N 3.23Å
405N88.2Confident87.7Confident93 Ų9346.2 Ų46.250%0.49723%0.23SC..SBendtrans-142.3104.6174.6-173.63.7000110.8L349 R401 F402L349-N405 WeakPolarHBondContact CD2-O 3.33Å; R401-N405 PolarHBondContact O-N 3.19Å; R401-N405 VanDerWaalsContact O-N 3.12Å; F402-N405 CarbonylContact O-C 3.43Å; F402-N405 VanDerWaalsContact O-O 3.12Å
406N86.5Confident87.1Confident0 Ų046.6 Ų46.60%023%0.234CC..SBendtrans-147.1-175.8179.755.158000112.4L349 I352 Y366 F402 I403 V408 T409 R410L349-N406 HydrophobicContact CD2-CB 3.97Å; I352-N406 HydrophobicContact CD1-CB 3.85Å; I352-N406 HydrophobicContact CG2-CB 4.15Å; Y366-N406 PolarHBondContact OH-ND2 3.24Å; Y366-N406 VanDerWaalsContact OH-ND2 3.08Å; F402-N406 WeakPolarHBondContact O-CB 2.98Å; F402-N406 PolarHBondContact O-ND2 3.36Å; I403-N406 PolarHBondContact O-ND2 3.34Å; N406-V408 VanDerWaalsContact C-N 3.31Å; N406-V408 PolarHBondContact O-N 2.89Å; N406-V408 WeakPolarHBondContact OD1-CA 3.49Å; N406-V408 VanDerWaalsContact OD1-CB 3.31Å; N406-V408 WeakPolarHBondContact OD1-CB 3.29Å; N406-V408 PolarHBondContact OD1-N 3.21Å; N406-T409 PolarHBondContact N-OG1 3.17Å; N406-T409 PolarHBondContact O-N 2.9Å; N406-T409 PolarHBondContact O-OG1 2.82Å; N406-T409 PolarHBondContact OD1-N 3.1Å; N406-R410 WeakPolarHBondContact O-CB 3.32Å; N406-R410 VanDerWaalsContact O-CG 3.32Å; N406-R410 WeakPolarHBondContact O-CG 3.38Å; N406-R410 PolarHBondContact O-N 3.11Å
407A83.1Confident86.9Confident13 Ų1345.9 Ų45.911%0.10723%0.228CC..Hα-helixtrans-55.4-43.5176.900000112.5I352 E353 R410 M411I352-A407 HydrophobicContact CG2-CB 4.48Å; E353-A407 HydrophobicContact CB-CB 4.25Å; A407-R410 PolarHBondContact O-N 2.93Å; A407-M411 WeakPolarHBondContact O-CB 3.44Å; A407-M411 WeakPolarHBondContact O-CG 3.28Å; A407-M411 PolarHBondContact O-N 3.16Å
408V83.6Confident86.7Confident1 Ų140.3 Ų40.31%0.00620%0.204CC..Hα-helixtrans-65.1-44.3-179174.70000111.7I352 A359 L360 Y366 N406 R410 M411 A412 K417 L421I352-V408 HydrophobicContact CG2-CG2 3.81Å; A359-V408 HydrophobicContact CB-CG2 3.88Å; L360-V408 HydrophobicContact CD1-CG1 3.83Å; Y366-V408 HydrophobicContact CD2-CB 4.48Å; Y366-V408 HydrophobicContact CD2-CG2 4.05Å; Y366-V408 HydrophobicContact CE2-CB 4.24Å; Y366-V408 HydrophobicContact CE2-CG2 4.19Å; N406-V408 VanDerWaalsContact C-N 3.31Å; N406-V408 PolarHBondContact O-N 2.89Å; N406-V408 WeakPolarHBondContact OD1-CA 3.49Å; N406-V408 VanDerWaalsContact OD1-CB 3.31Å; N406-V408 WeakPolarHBondContact OD1-CB 3.29Å; N406-V408 PolarHBondContact OD1-N 3.21Å; V408-R410 VanDerWaalsContact C-N 3.31Å; V408-R410 PolarHBondContact O-N 3.49Å; V408-M411 PolarHBondContact O-N 3.47Å; V408-A412 WeakPolarHBondContact O-CB 3.4Å; V408-A412 PolarHBondContact O-N 3.24Å; V408-K417 HydrophobicContact CG1-CG 3.77Å; V408-L421 HydrophobicContact CG1-CD1 3.79Å
409T83.8Confident86.6Confident7 Ų740.3 Ų40.34%0.04320%0.204CC..Hα-helixtrans-67.3-33.2176.7590000112.2N406 Q413 S414 S418N406-T409 PolarHBondContact N-OG1 3.17Å; N406-T409 PolarHBondContact O-N 2.9Å; N406-T409 PolarHBondContact O-OG1 2.82Å; N406-T409 PolarHBondContact OD1-N 3.1Å; T409-Q413 PolarHBondContact O-N 3.37Å; T409-Q413 VanDerWaalsContact O-N 3.09Å; T409-S414 WeakPolarHBondContact CA-O 3.32Å; T409-S414 WeakPolarHBondContact CB-O 3.2Å; T409-S414 PolarHBondContact O-N 3.26Å; T409-S418 WeakPolarHBondContact CG2-OG 3.1Å
410R84Confident86.4Confident140 Ų14040.4 Ų40.453%0.52821%0.205SC..Hα-helixtrans-68.8-46.4175.1-74.4-174.4-66.6161.80.3111.7N406 A407 V408 A412 Q413N406-R410 WeakPolarHBondContact O-CB 3.32Å; N406-R410 VanDerWaalsContact O-CG 3.32Å; N406-R410 WeakPolarHBondContact O-CG 3.38Å; N406-R410 PolarHBondContact O-N 3.11Å; A407-R410 PolarHBondContact O-N 2.93Å; V408-R410 VanDerWaalsContact C-N 3.31Å; V408-R410 PolarHBondContact O-N 3.49Å; R410-A412 VanDerWaalsContact C-N 3.3Å; R410-A412 PolarHBondContact O-N 2.77Å; R410-Q413 PolarHBondContact O-N 2.62Å
411M80.1Confident86.4Confident94 Ų9439.6 Ų39.646%0.46320%0.196SC..Hα-helixtrans-61.4-39.4176.5-70171.678.300111.8E357 L360 A407 V408 Q413E357-M411 HydrophobicContact CG-CE 3.9Å; L360-M411 HydrophobicContact CD2-CE 4.31Å; A407-M411 WeakPolarHBondContact O-CB 3.44Å; A407-M411 WeakPolarHBondContact O-CG 3.28Å; A407-M411 PolarHBondContact O-N 3.16Å; V408-M411 PolarHBondContact O-N 3.47Å; M411-Q413 VanDerWaalsContact C-N 3.27Å; M411-Q413 PolarHBondContact O-N 3.26Å
412A78Confident86.5Confident39 Ų3933.4 Ų33.432%0.32217%0.172SC..THydrogen-bonded Turntrans-81-1.7176.400000114L360 V408 R410 S414 K417L360-A412 HydrophobicContact CD1-CB 4.39Å; V408-A412 WeakPolarHBondContact O-CB 3.4Å; V408-A412 PolarHBondContact O-N 3.24Å; R410-A412 VanDerWaalsContact C-N 3.3Å; R410-A412 PolarHBondContact O-N 2.77Å; A412-S414 PolarHBondContact O-N 3.32Å; A412-K417 HydrophobicContact CB-CB 3.8Å; A412-K417 HydrophobicContact CB-CD 4.24Å; A412-K417 HydrophobicContact CB-CG 3.84Å
413Q78.6Confident86.5Confident185 Ų18533.4 Ų33.486%0.86417%0.172SC*.THydrogen-bonded Turntrans50.227.2-173.2-60.5-176.5-17.900114.2T409 R410 M411T409-Q413 PolarHBondContact O-N 3.37Å; T409-Q413 VanDerWaalsContact O-N 3.09Å; R410-Q413 PolarHBondContact O-N 2.62Å; M411-Q413 VanDerWaalsContact C-N 3.27Å; M411-Q413 PolarHBondContact O-N 3.26Å
414S78.2Confident86.6Confident34 Ų3436.9 Ų36.924%0.23819%0.185CC..  trans-156.4127.7-173.4-176.30000112.4T409 A412 S416 K417T409-S414 WeakPolarHBondContact CA-O 3.32Å; T409-S414 WeakPolarHBondContact CB-O 3.2Å; T409-S414 PolarHBondContact O-N 3.26Å; A412-S414 PolarHBondContact O-N 3.32Å; S414-S416 PolarHBondContact O-N 3.34Å; S414-S416 VanDerWaalsContact OG-CB 3.32Å; S414-S416 WeakPolarHBondContact OG-CB 3.32Å; S414-S416 PolarHBondContact OG-N 3.14Å; S414-S416 PolarHBondContact OG-OG 3.42Å; S414-K417 PolarHBondContact O-N 2.81Å
415S78.1Confident86.8Confident33 Ų3336.8 Ų36.823%0.23118%0.184CC..THydrogen-bonded Turntrans-61.9-21.4169.655.20000112.4K417 P419 D458S415-K417 PolarHBondContact O-N 3.39Å; S415-K417 VanDerWaalsContact O-N 3.16Å; S415-P419 VanDerWaalsContact O-CD 3.26Å; S415-P419 WeakPolarHBondContact O-CD 3.22Å; S415-D458 PolarHBondContact OG-OD2 3.38Å
416S84.6Confident87.1Confident11 Ų1132.4 Ų32.48%0.07716%0.16CC..THydrogen-bonded Turntrans-71.4-5.5-179.5-51.40000113.4S414 P419 E420S414-S416 PolarHBondContact O-N 3.34Å; S414-S416 VanDerWaalsContact OG-CB 3.32Å; S414-S416 WeakPolarHBondContact OG-CB 3.32Å; S414-S416 PolarHBondContact OG-N 3.14Å; S414-S416 PolarHBondContact OG-OG 3.42Å; S416-P419 WeakPolarHBondContact O-CD 3.46Å; S416-E420 WeakPolarHBondContact O-CB 3.31Å; S416-E420 PolarHBondContact O-N 2.96Å
417K88.9Confident87.4Confident30 Ų3033.8 Ų33.813%0.1317%0.168CC..Hα-helixtrans-71.7-39.2176.5-168.362.4178.8177.50113L360 V408 A412 S414 S415 E420 L421L360-K417 HydrophobicContact CD1-CG 4.34Å; V408-K417 HydrophobicContact CG1-CG 3.77Å; A412-K417 HydrophobicContact CB-CB 3.8Å; A412-K417 HydrophobicContact CB-CD 4.24Å; A412-K417 HydrophobicContact CB-CG 3.84Å; S414-K417 PolarHBondContact O-N 2.81Å; S415-K417 PolarHBondContact O-N 3.39Å; S415-K417 VanDerWaalsContact O-N 3.16Å; K417-E420 IonicContact NZ-OE1 3.41Å; K417-E420 PolarHBondContact NZ-OE1 3.08Å; K417-E420 VanDerWaalsContact NZ-OE1 3.08Å; K417-E420 WeakPolarHBondContact O-CB 3.41Å; K417-E420 PolarHBondContact O-N 3.23Å; K417-L421 HydrophobicContact CD-CG 4.45Å; K417-L421 HydrophobicContact CG-CD1 4.17Å; K417-L421 HydrophobicContact CG-CG 4.37Å; K417-L421 WeakPolarHBondContact O-CG 3.19Å; K417-L421 PolarHBondContact O-N 3.01Å
418S91.3Very high87.8Confident0 Ų036.2 Ų36.20%018%0.184CC..Hα-helixtrans-61.6-48.9178.7-47.10000112.8Y366 I403 T409 E420 L421 L422Y366-S418 VanDerWaalsContact OH-CB 3.28Å; Y366-S418 WeakPolarHBondContact OH-CB 3.36Å; Y366-S418 PolarHBondContact OH-OG 3.21Å; I403-S418 WeakPolarHBondContact O-CB 3.34Å; I403-S418 PolarHBondContact O-OG 3.18Å; T409-S418 WeakPolarHBondContact CG2-OG 3.1Å; S418-E420 VanDerWaalsContact C-N 3.32Å; S418-E420 PolarHBondContact O-N 3.38Å; S418-L421 PolarHBondContact O-N 3.26Å; S418-L422 PolarHBondContact O-N 3.49Å
419P93.1Very high88.2Confident0 Ų037.1 Ų37.10%019%0.189CC..Hα-helixtrans-61.5-36.7173.7-14.322.2000113.3S415 S416 L422 A423 I456 D458 V461 F462S415-P419 VanDerWaalsContact O-CD 3.26Å; S415-P419 WeakPolarHBondContact O-CD 3.22Å; S416-P419 WeakPolarHBondContact O-CD 3.46Å; P419-L422 PolarHBondContact O-N 3.29Å; P419-A423 WeakPolarHBondContact O-CB 3.49Å; P419-A423 PolarHBondContact O-N 3.49Å; P419-I456 HydrophobicContact CB-CG2 4.03Å; P419-I456 HydrophobicContact CG-CD1 4.34Å; P419-I456 HydrophobicContact CG-CG2 3.72Å; P419-D458 HydrophobicContact CG-CB 3.99Å; P419-D458 WeakPolarHBondContact CG-O 3.45Å; P419-V461 HydrophobicContact CB-CB 3.98Å; P419-V461 HydrophobicContact CB-CG1 3.99Å; P419-V461 HydrophobicContact CG-CB 4.25Å; P419-V461 HydrophobicContact CG-CG1 4.39Å; P419-F462 HydrophobicContact CB-CB 4Å
420E91.9Very high88.7Confident2 Ų236.8 Ų36.81%0.00919%0.187CC..Hα-helixtrans-63.4-47.6177.2-173.6-160.4121.500111.4S416 K417 S418 L422 A423 R424 F465 Q696 H700S416-E420 WeakPolarHBondContact O-CB 3.31Å; S416-E420 PolarHBondContact O-N 2.96Å; K417-E420 IonicContact NZ-OE1 3.41Å; K417-E420 PolarHBondContact NZ-OE1 3.08Å; K417-E420 VanDerWaalsContact NZ-OE1 3.08Å; K417-E420 WeakPolarHBondContact O-CB 3.41Å; K417-E420 PolarHBondContact O-N 3.23Å; S418-E420 VanDerWaalsContact C-N 3.32Å; S418-E420 PolarHBondContact O-N 3.38Å; E420-L422 VanDerWaalsContact C-N 3.34Å; E420-A423 PolarHBondContact O-N 3.04Å; E420-R424 WeakPolarHBondContact O-CG 3.26Å; E420-R424 PolarHBondContact O-N 2.92Å; E420-R424 IonicContact OE1-CZ 3.66Å; E420-R424 IonicContact OE1-NE 2.72Å; E420-R424 PolarHBondContact OE1-NE 3.49Å; E420-R424 IonicContact OE1-NH2 2.6Å; E420-R424 PolarHBondContact OE1-NH2 2.76Å; E420-R424 VanDerWaalsContact OE1-NH2 3.1Å; E420-F465 HydrophobicContact CB-CD2 4.18Å; E420-F465 HydrophobicContact CB-CE2 4.19Å; E420-F465 HydrophobicContact CG-CD1 3.99Å; E420-F465 HydrophobicContact CG-CD2 3.99Å; E420-F465 HydrophobicContact CG-CE1 3.87Å; E420-F465 HydrophobicContact CG-CE2 3.89Å; E420-F465 HydrophobicContact CG-CG 4.06Å; E420-F465 HydrophobicContact CG-CZ 3.84Å; E420-Q696 PolarHBondContact OE1-NE2 3.09Å; E420-Q696 PolarHBondContact OE2-NE2 2.98Å; E420-H700 IonicContact OE2-CE1 2.74Å; E420-H700 IonicContact OE2-NE2 3.29Å; E420-H700 PolarHBondContact OE2-NE2 3.03Å
421L92.7Very high89.1Confident2 Ų234.7 Ų34.71%0.0118%0.181CC..Hα-helixtrans-62.7-42.3177.3-71.7174.4000111A359 P363 Y366 V408 K417 S418 A423 R424 Y425A359-L421 WeakPolarHBondContact O-CD1 3.44Å; P363-L421 HydrophobicContact CB-CD2 4.48Å; P363-L421 WeakPolarHBondContact CB-O 3.44Å; P363-L421 HydrophobicContact CG-CD2 4.08Å; Y366-L421 HydrophobicContact CD1-CB 4.14Å; Y366-L421 HydrophobicContact CD1-CD1 4.16Å; Y366-L421 HydrophobicContact CD2-CD1 4.15Å; Y366-L421 HydrophobicContact CG-CD1 3.89Å; V408-L421 HydrophobicContact CG1-CD1 3.79Å; K417-L421 HydrophobicContact CD-CG 4.45Å; K417-L421 HydrophobicContact CG-CD1 4.17Å; K417-L421 HydrophobicContact CG-CG 4.37Å; K417-L421 WeakPolarHBondContact O-CG 3.19Å; K417-L421 PolarHBondContact O-N 3.01Å; S418-L421 PolarHBondContact O-N 3.26Å; L421-A423 VanDerWaalsContact C-N 3.34Å; L421-A423 PolarHBondContact O-N 3.06Å; L421-R424 PolarHBondContact O-N 3.01Å; L421-Y425 PolarHBondContact O-N 3.07Å
422L95.2Very high89.4Confident1 Ų137 Ų371%0.00519%0.189CC..Hα-helixtrans-59.6-44.5175.4-169.265.7000111.5V367 S418 P419 E420 R424 Y425 C426 V449 V452 F453 I456 F462V367-L422 HydrophobicContact CG1-CD1 4.05Å; V367-L422 HydrophobicContact CG2-CD1 3.69Å; S418-L422 PolarHBondContact O-N 3.49Å; P419-L422 PolarHBondContact O-N 3.29Å; E420-L422 VanDerWaalsContact C-N 3.34Å; L422-R424 PolarHBondContact O-N 3.42Å; L422-Y425 PolarHBondContact O-N 3.49Å; L422-C426 PolarHBondContact O-N 3.28Å; L422-C426 PolarHBondContact O-SG 3.1Å; L422-V449 HydrophobicContact CD1-CG1 3.98Å; L422-V449 HydrophobicContact CG-CG1 4.31Å; L422-V452 HydrophobicContact CD1-CB 4.21Å; L422-V452 HydrophobicContact CD1-CG1 4.16Å; L422-V452 HydrophobicContact CD2-CG1 4.31Å; L422-F453 HydrophobicContact CD2-CB 3.98Å; L422-F453 HydrophobicContact CD2-CD2 4.23Å; L422-I456 HydrophobicContact CD2-CG1 4.1Å; L422-F462 HydrophobicContact CB-CD2 4.14Å; L422-F462 HydrophobicContact CB-CE2 4.26Å; L422-F462 HydrophobicContact CD2-CD2 4.14Å; L422-F462 HydrophobicContact CD2-CE2 4.16Å; L422-F462 HydrophobicContact CG-CD2 4.16Å; L422-F462 HydrophobicContact CG-CE2 3.93Å
423A94.8Very high89.8Confident0 Ų038 Ų380%019%0.194CC..Hα-helixtrans-63.3-40.2176.800000112.6P419 E420 L421 C426 D427 F462 F465P419-A423 WeakPolarHBondContact O-CB 3.49Å; P419-A423 PolarHBondContact O-N 3.49Å; E420-A423 PolarHBondContact O-N 3.04Å; L421-A423 VanDerWaalsContact C-N 3.34Å; L421-A423 PolarHBondContact O-N 3.06Å; A423-C426 PolarHBondContact O-N 3.15Å; A423-D427 PolarHBondContact O-N 2.87Å; A423-F462 HydrophobicContact CB-CD2 3.73Å; A423-F462 HydrophobicContact CB-CE2 3.9Å; A423-F462 HydrophobicContact CB-CG 4.39Å; A423-F465 HydrophobicContact CB-CB 3.78Å
424R93Very high89.7Confident76 Ų7635.3 Ų35.329%0.28720%0.195SC..Hα-helixtrans-64.5-38.6174.7-74.6177-173.8-89.55.4112.3P363 E420 L421 L422 D427 S428 M469P363-R424 HydrophobicContact CB-CB 4.11Å; P363-R424 HydrophobicContact CG-CB 3.61Å; E420-R424 WeakPolarHBondContact O-CG 3.26Å; E420-R424 PolarHBondContact O-N 2.92Å; E420-R424 IonicContact OE1-CZ 3.66Å; E420-R424 IonicContact OE1-NE 2.72Å; E420-R424 PolarHBondContact OE1-NE 3.49Å; E420-R424 IonicContact OE1-NH2 2.6Å; E420-R424 PolarHBondContact OE1-NH2 2.76Å; E420-R424 VanDerWaalsContact OE1-NH2 3.1Å; L421-R424 PolarHBondContact O-N 3.01Å; L422-R424 PolarHBondContact O-N 3.42Å; R424-D427 PolarHBondContact O-N 3.26Å; R424-S428 PolarHBondContact O-N 3.2Å; R424-M469 HydrophobicContact CB-CE 4.38Å; R424-M469 HydrophobicContact CG-CE 3.45Å; R424-M469 VanDerWaalsContact CG-CE 3.45Å; R424-M469 HydrophobicContact CG-SD 4.33Å
425Y94.7Very high89.9Confident12 Ų1242.4 Ų42.45%0.04722%0.222CC..Hα-helixtrans-63.6-47175.5-176.1-122000110.7K364 V367 L421 L422 D427 S428 L429 T445 V449K364-Y425 HydrophobicContact CB-CD2 3.92Å; K364-Y425 HydrophobicContact CB-CE2 3.7Å; K364-Y425 HydrophobicContact CD-CE2 4.39Å; K364-Y425 HydrophobicContact CG-CD2 4.42Å; K364-Y425 HydrophobicContact CG-CE2 3.69Å; V367-Y425 HydrophobicContact CB-CD1 3.8Å; V367-Y425 HydrophobicContact CB-CE1 4.13Å; V367-Y425 HydrophobicContact CB-CG 4.19Å; V367-Y425 HydrophobicContact CG1-CD1 3.64Å; V367-Y425 HydrophobicContact CG1-CE1 3.74Å; V367-Y425 HydrophobicContact CG2-CD1 3.88Å; V367-Y425 HydrophobicContact CG2-CG 4.03Å; L421-Y425 PolarHBondContact O-N 3.07Å; L422-Y425 PolarHBondContact O-N 3.49Å; Y425-D427 VanDerWaalsContact C-N 3.32Å; Y425-D427 PolarHBondContact O-N 3.23Å; Y425-S428 PolarHBondContact O-N 2.86Å; Y425-S428 VanDerWaalsContact O-N 3.09Å; Y425-S428 PolarHBondContact O-OG 3.25Å; Y425-L429 HydrophobicContact CD1-CD1 4.1Å; Y425-L429 HydrophobicContact CE1-CD1 3.74Å; Y425-L429 HydrophobicContact CE1-CG 4.46Å; Y425-L429 HydrophobicContact CE2-CD1 4.48Å; Y425-L429 HydrophobicContact CE2-CD2 4.29Å; Y425-L429 HydrophobicContact CE2-CG 4.35Å; Y425-L429 WeakPolarHBondContact O-CG 3.2Å; Y425-L429 PolarHBondContact O-N 3.13Å; Y425-L429 VanDerWaalsContact O-N 3.13Å; Y425-T445 HydrophobicContact CE1-CG2 4.46Å; Y425-V449 HydrophobicContact CD1-CG2 3.8Å; Y425-V449 HydrophobicContact CE1-CG2 3.83Å
426C94.4Very high90.1Very high0 Ų043.2 Ų43.20%022%0.224CC..Hα-helixtrans-56.6-43.8173.5-59.40000112.7L422 A423 S428 L429 L430 V449 Y466L422-C426 PolarHBondContact O-N 3.28Å; L422-C426 PolarHBondContact O-SG 3.1Å; A423-C426 PolarHBondContact O-N 3.15Å; C426-S428 VanDerWaalsContact C-N 3.31Å; C426-S428 PolarHBondContact O-N 3.36Å; C426-L429 PolarHBondContact O-N 2.67Å; C426-L430 WeakPolarHBondContact O-CB 3.27Å; C426-L430 WeakPolarHBondContact O-CG 3.42Å; C426-L430 PolarHBondContact O-N 3.02Å; C426-V449 WeakPolarHBondContact SG-CG1 3.37Å; C426-Y466 HydrophobicContact CB-CD2 4.22Å; C426-Y466 HydrophobicContact CB-CE2 4.03Å
427D93.3Very high90Very high30 Ų3045 Ų4516%0.1624%0.235CC..Hα-helixtrans-59.3-42.6175.9178.870.5000111.7A423 R424 Y425 L429 L430 K431 M469 R473A423-D427 PolarHBondContact O-N 2.87Å; R424-D427 PolarHBondContact O-N 3.26Å; Y425-D427 VanDerWaalsContact C-N 3.32Å; Y425-D427 PolarHBondContact O-N 3.23Å; D427-L429 VanDerWaalsContact C-N 3.28Å; D427-L429 PolarHBondContact O-N 3.44Å; D427-L430 PolarHBondContact O-N 3.42Å; D427-K431 VanDerWaalsContact O-CB 3.23Å; D427-K431 WeakPolarHBondContact O-CB 3.47Å; D427-K431 PolarHBondContact O-N 2.93Å; D427-M469 HydrophobicContact CB-CB 4.05Å; D427-M469 HydrophobicContact CB-CG 4.17Å; D427-M469 HydrophobicContact CB-SD 3.58Å; D427-M469 VanDerWaalsContact CB-SD 3.58Å; D427-M469 WeakPolarHBondContact OD1-CB 3.31Å; D427-R473 WeakPolarHBondContact OD1-CD 3.09Å; D427-R473 IonicContact OD1-CZ 3.17Å; D427-R473 IonicContact OD1-NE 3.43Å; D427-R473 IonicContact OD1-NH1 3.6Å; D427-R473 PolarHBondContact OD1-NH1 2.92Å
428S92.4Very high90Very high63 Ų6350.6 Ų50.644%0.44126%0.262SS..Hα-helixtrans-63.7-32.7178.776.50000113.4R424 Y425 C426R424-S428 PolarHBondContact O-N 3.2Å; Y425-S428 PolarHBondContact O-N 2.86Å; Y425-S428 VanDerWaalsContact O-N 3.09Å; Y425-S428 PolarHBondContact O-OG 3.25Å; C426-S428 VanDerWaalsContact C-N 3.31Å; C426-S428 PolarHBondContact O-N 3.36Å
429L91.9Very high89.8Confident21 Ų2157.5 Ų57.511%0.1129%0.294CS..Hα-helixtrans-75.5-40.3177.1-65.4174.1000112.2Y425 C426 D427 L442 T445 L446 V449Y425-L429 HydrophobicContact CD1-CD1 4.1Å; Y425-L429 HydrophobicContact CE1-CD1 3.74Å; Y425-L429 HydrophobicContact CE1-CG 4.46Å; Y425-L429 HydrophobicContact CE2-CD1 4.48Å; Y425-L429 HydrophobicContact CE2-CD2 4.29Å; Y425-L429 HydrophobicContact CE2-CG 4.35Å; Y425-L429 WeakPolarHBondContact O-CG 3.2Å; Y425-L429 PolarHBondContact O-N 3.13Å; Y425-L429 VanDerWaalsContact O-N 3.13Å; C426-L429 PolarHBondContact O-N 2.67Å; D427-L429 VanDerWaalsContact C-N 3.28Å; D427-L429 PolarHBondContact O-N 3.44Å; L429-L442 HydrophobicContact CB-CD1 4.05Å; L429-T445 HydrophobicContact CD1-CG2 3.63Å; L429-T445 HydrophobicContact CD2-CG2 4.14Å; L429-L446 HydrophobicContact CD1-CD2 4.48Å; L429-V449 HydrophobicContact CD1-CG2 4.3Å
430L93.2Very high89.7Confident0 Ų060.8 Ų60.80%032%0.321CS..Hα-helixtrans-88.4-4.1-175-67.2169.2000113.3C426 D427 L446 Y466 S479 A480 A484 M488C426-L430 WeakPolarHBondContact O-CB 3.27Å; C426-L430 WeakPolarHBondContact O-CG 3.42Å; C426-L430 PolarHBondContact O-N 3.02Å; D427-L430 PolarHBondContact O-N 3.42Å; L430-L446 HydrophobicContact CD2-CD1 4.23Å; L430-L446 HydrophobicContact CD2-CD2 4.4Å; L430-L446 HydrophobicContact CG-CD2 4.45Å; L430-Y466 HydrophobicContact CD1-CE2 4.22Å; L430-Y466 WeakPolarHBondContact CD1-OH 3.45Å; L430-S479 CarbonylContact O-C 3.52Å; L430-S479 WeakPolarHBondContact O-CA 3.23Å; L430-A480 WeakPolarHBondContact O-CB 3.49Å; L430-A480 PolarHBondContact O-N 3.09Å; L430-A484 HydrophobicContact CD2-CB 3.9Å; L430-M488 HydrophobicContact CD1-CB 4.32Å; L430-M488 HydrophobicContact CD1-CG 4.27Å
431K91.9Very high89.6Confident95 Ų9566 Ų6641%0.41335%0.345SS..BIsolated β-bridgetrans-81.9140.2175.4-167.9173.6-177.5176.40110.4D427 S433 N436 N478D427-K431 VanDerWaalsContact O-CB 3.23Å; D427-K431 WeakPolarHBondContact O-CB 3.47Å; D427-K431 PolarHBondContact O-N 2.93Å; K431-S433 PolarHBondContact O-N 3Å; K431-N436 PolarHBondContact O-ND2 3.17Å; K431-N436 PolarHBondContact O-OD1 3.01Å; K431-N478 WeakPolarHBondContact CA-O 3.49Å; K431-N478 WeakPolarHBondContact CE-ND2 3.44Å; K431-N478 WeakPolarHBondContact CG-ND2 3.31Å
432K88.3Confident89.6Confident143 Ų14366.4 Ų66.462%0.62235%0.347SS*.  trans-61.2121175.4-169.3174.9-175.8170.40110.2N478K432-N478 PolarHBondContact N-O 3.37Å
433S85.3Confident89.4Confident61 Ų6169 Ų6943%0.42736%0.359SS..  trans-148152.6174.4158.50000110K431 K435 N436K431-S433 PolarHBondContact O-N 3Å; S433-K435 PolarHBondContact O-N 3.36Å; S433-K435 PolarHBondContact OG-N 2.97Å; S433-N436 WeakPolarHBondContact CA-OD1 3.29Å; S433-N436 WeakPolarHBondContact CB-OD1 3.15Å; S433-N436 PolarHBondContact N-ND2 3.34Å; S433-N436 PolarHBondContact N-OD1 2.99Å; S433-N436 VanDerWaalsContact O-CG 3.24Å; S433-N436 PolarHBondContact O-N 3.01Å; S433-N436 PolarHBondContact O-OD1 3.36Å
434S76.5Confident89.4Confident127 Ų12773.6 Ų73.689%0.88838%0.384SS*.THydrogen-bonded Turntrans-68.7-7.6176.962.10000113.2
435K82.6Confident89.3Confident184 Ų18471.5 Ų71.580%0.838%0.379SS*.THydrogen-bonded Turntrans-108.115.1178-60.1-174.2178.1-1760112.5S433S433-K435 PolarHBondContact O-N 3.36Å; S433-K435 PolarHBondContact OG-N 2.97Å
436N82.3Confident89.3Confident50 Ų5070.9 Ų70.927%0.26738%0.377SS..PPolyproline II helixtrans-65.2133179.5-73.512.5000109.3K431 S433 A480K431-N436 PolarHBondContact O-ND2 3.17Å; K431-N436 PolarHBondContact O-OD1 3.01Å; S433-N436 WeakPolarHBondContact CA-OD1 3.29Å; S433-N436 WeakPolarHBondContact CB-OD1 3.15Å; S433-N436 PolarHBondContact N-ND2 3.34Å; S433-N436 PolarHBondContact N-OD1 2.99Å; S433-N436 VanDerWaalsContact O-CG 3.24Å; S433-N436 PolarHBondContact O-N 3.01Å; S433-N436 PolarHBondContact O-OD1 3.36Å; N436-A480 WeakPolarHBondContact ND2-CB 3.29Å
437P81.9Confident89.3Confident49 Ų4973.9 Ų73.932%0.31839%0.393SS..PPolyproline II helixtrans-66167.6176.828.3-32.7000110.8E441 L442P437-E441 HydrophobicContact CB-CB 4.01Å; P437-L442 HydrophobicContact CG-CB 4.12Å; P437-L442 HydrophobicContact CG-CD1 4.24Å
438E88.6Confident89.3Confident147 Ų14775.1 Ų75.169%0.68740%0.398SS*.PPolyproline II helixtrans-60.5155.8173.6-65.6-172.8174.100111A440 E441 L442E438-A440 VanDerWaalsContact C-N 3.26Å; E438-A440 PolarHBondContact O-N 3.39Å; E438-E441 PolarHBondContact O-N 2.91Å; E438-E441 VanDerWaalsContact O-N 3.14Å; E438-L442 WeakPolarHBondContact O-CB 3.36Å; E438-L442 PolarHBondContact O-N 3.26Å
439E87.6Confident89.4Confident145 Ų14572.1 Ų72.168%0.67838%0.377SS*.Hα-helixtrans-57-38.2-173.6-69.3-172.4157.200113L442 E443E439-L442 PolarHBondContact O-N 3.42Å; E439-E443 WeakPolarHBondContact O-CB 3.29Å; E439-E443 PolarHBondContact O-N 3.38Å
440A90.8Very high89.5Confident68 Ų6872.4 Ų72.456%0.56238%0.378SS*.Hα-helixtrans-66.2-46.7177.500000112.3E438 L442 E443 D444E438-A440 VanDerWaalsContact C-N 3.26Å; E438-A440 PolarHBondContact O-N 3.39Å; A440-L442 VanDerWaalsContact C-N 3.32Å; A440-L442 PolarHBondContact O-N 3.03Å; A440-E443 PolarHBondContact O-N 3.07Å; A440-D444 PolarHBondContact O-N 3.2Å
441E91.3Very high89.6Confident113 Ų11374.8 Ų74.853%0.52839%0.392SS..Hα-helixtrans-65.4-36.5177.5-67.3-174.2164.300112P437 E438 D444 T445P437-E441 HydrophobicContact CB-CB 4.01Å; E438-E441 PolarHBondContact O-N 2.91Å; E438-E441 VanDerWaalsContact O-N 3.14Å; E441-D444 PolarHBondContact O-N 3.19Å; E441-T445 WeakPolarHBondContact O-CB 3.33Å; E441-T445 PolarHBondContact O-N 2.86Å; E441-T445 PolarHBondContact O-OG1 3.44Å
442L90.9Very high89.7Confident10 Ų1070.4 Ų70.45%0.05237%0.374CS..Hα-helixtrans-61.6-48.2174.5-178.159.2000110.6L429 P437 E438 E439 A440 D444 T445 L446 A484L429-L442 HydrophobicContact CB-CD1 4.05Å; P437-L442 HydrophobicContact CG-CB 4.12Å; P437-L442 HydrophobicContact CG-CD1 4.24Å; E438-L442 WeakPolarHBondContact O-CB 3.36Å; E438-L442 PolarHBondContact O-N 3.26Å; E439-L442 PolarHBondContact O-N 3.42Å; A440-L442 VanDerWaalsContact C-N 3.32Å; A440-L442 PolarHBondContact O-N 3.03Å; L442-D444 PolarHBondContact O-N 2.77Å; L442-T445 WeakPolarHBondContact O-CB 3.49Å; L442-T445 PolarHBondContact O-N 2.77Å; L442-T445 VanDerWaalsContact O-N 3.15Å; L442-L446 HydrophobicContact CG-CD1 4.47Å; L442-L446 WeakPolarHBondContact O-CG 3.42Å; L442-L446 PolarHBondContact O-N 3.44Å; L442-A484 HydrophobicContact CD2-CB 3.93Å
443E92.6Very high90Very high55 Ų5563.7 Ų63.726%0.25734%0.344SS..Hα-helixtrans-61.5-42.1178.9-176.863.8-164.100111.8E439 A440 T445 L446 N447 S487 K491E439-E443 WeakPolarHBondContact O-CB 3.29Å; E439-E443 PolarHBondContact O-N 3.38Å; A440-E443 PolarHBondContact O-N 3.07Å; E443-T445 VanDerWaalsContact C-N 3.31Å; E443-T445 PolarHBondContact O-N 3.32Å; E443-L446 PolarHBondContact O-N 2.99Å; E443-N447 PolarHBondContact O-N 3.48Å; E443-N447 PolarHBondContact O-ND2 3.31Å; E443-N447 VanDerWaalsContact O-ND2 3.16Å; E443-S487 PolarHBondContact OE1-OG 3.48Å; E443-S487 VanDerWaalsContact OE1-OG 3.11Å; E443-S487 PolarHBondContact OE2-OG 3.47Å; E443-K491 WeakPolarHBondContact OE1-CE 3.29Å; E443-K491 IonicContact OE1-NZ 3.84Å; E443-K491 PolarHBondContact OE1-NZ 3.22Å
444D93.1Very high90.4Very high96 Ų9666.2 Ų66.251%0.51335%0.348SS..Hα-helixtrans-61.9-39.6173.5-80.1-16.3000112.3A440 E441 L442 N447 Q448A440-D444 PolarHBondContact O-N 3.2Å; E441-D444 PolarHBondContact O-N 3.19Å; L442-D444 PolarHBondContact O-N 2.77Å; D444-N447 PolarHBondContact O-N 2.86Å; D444-Q448 WeakPolarHBondContact O-CG 3.47Å; D444-Q448 PolarHBondContact O-N 3.21Å
445T92Very high91.2Very high32 Ų3261.2 Ų61.220%0.19631%0.31CS..Hα-helixtrans-66.2-39.6175.8-54.20000111.2Y425 L429 E441 L442 E443 N447 Q448 V449Y425-T445 HydrophobicContact CE1-CG2 4.46Å; L429-T445 HydrophobicContact CD1-CG2 3.63Å; L429-T445 HydrophobicContact CD2-CG2 4.14Å; E441-T445 WeakPolarHBondContact O-CB 3.33Å; E441-T445 PolarHBondContact O-N 2.86Å; E441-T445 PolarHBondContact O-OG1 3.44Å; L442-T445 WeakPolarHBondContact O-CB 3.49Å; L442-T445 PolarHBondContact O-N 2.77Å; L442-T445 VanDerWaalsContact O-N 3.15Å; E443-T445 VanDerWaalsContact C-N 3.31Å; E443-T445 PolarHBondContact O-N 3.32Å; T445-N447 VanDerWaalsContact C-N 3.35Å; T445-Q448 WeakPolarHBondContact O-CB 3.44Å; T445-Q448 PolarHBondContact O-N 3.07Å; T445-V449 WeakPolarHBondContact O-CG2 3.3Å; T445-V449 PolarHBondContact O-N 2.94Å
446L93.8Very high91.7Very high0 Ų052.6 Ų52.60%027%0.272CS..Hα-helixtrans-64.9-37.6174.4-67176.1000111.8L429 L430 L442 E443 Q448 V449 M450 M488L429-L446 HydrophobicContact CD1-CD2 4.48Å; L430-L446 HydrophobicContact CD2-CD1 4.23Å; L430-L446 HydrophobicContact CD2-CD2 4.4Å; L430-L446 HydrophobicContact CG-CD2 4.45Å; L442-L446 HydrophobicContact CG-CD1 4.47Å; L442-L446 WeakPolarHBondContact O-CG 3.42Å; L442-L446 PolarHBondContact O-N 3.44Å; E443-L446 PolarHBondContact O-N 2.99Å; L446-Q448 VanDerWaalsContact C-N 3.33Å; L446-Q448 PolarHBondContact O-N 3.37Å; L446-V449 WeakPolarHBondContact O-CB 3.49Å; L446-V449 PolarHBondContact O-N 3.3Å; L446-M450 WeakPolarHBondContact O-CG 3.4Å; L446-M450 PolarHBondContact O-N 3.37Å; L446-M450 VanDerWaalsContact O-N 3.1Å; L446-M488 HydrophobicContact CB-SD 4.49Å; L446-M488 HydrophobicContact CD2-SD 4.03Å
447N94.8Very high92Very high63 Ų6353.9 Ų53.934%0.33728%0.277SS..Hα-helixtrans-61.9-41.7172.9-71.3-39.7000111.5E443 D444 T445 M450 V451 K491E443-N447 PolarHBondContact O-N 3.48Å; E443-N447 PolarHBondContact O-ND2 3.31Å; E443-N447 VanDerWaalsContact O-ND2 3.16Å; D444-N447 PolarHBondContact O-N 2.86Å; T445-N447 VanDerWaalsContact C-N 3.35Å; N447-M450 WeakPolarHBondContact O-CB 3.28Å; N447-M450 PolarHBondContact O-N 2.97Å; N447-M450 VanDerWaalsContact O-N 3.17Å; N447-V451 PolarHBondContact O-N 3.25Å; N447-K491 WeakPolarHBondContact OD1-CE 3.41Å; N447-K491 PolarHBondContact OD1-NZ 3.44Å
448Q93.8Very high92.4Very high55 Ų5551.9 Ų51.926%0.25726%0.263SS..Hα-helixtrans-64.2-42.3175.6-68.517540.900112L371 D444 T445 L446 M450 V451 V452L371-Q448 HydrophobicContact CD1-CB 3.87Å; L371-Q448 HydrophobicContact CD2-CB 3.98Å; L371-Q448 WeakPolarHBondContact CD2-O 3.32Å; D444-Q448 WeakPolarHBondContact O-CG 3.47Å; D444-Q448 PolarHBondContact O-N 3.21Å; T445-Q448 WeakPolarHBondContact O-CB 3.44Å; T445-Q448 PolarHBondContact O-N 3.07Å; L446-Q448 VanDerWaalsContact C-N 3.33Å; L446-Q448 PolarHBondContact O-N 3.37Å; Q448-M450 PolarHBondContact O-N 3.03Å; Q448-V451 VanDerWaalsContact O-CB 3.29Å; Q448-V451 WeakPolarHBondContact O-CB 3.5Å; Q448-V451 PolarHBondContact O-N 3Å; Q448-V452 PolarHBondContact O-N 2.82Å
449V94.3Very high92.6Very high0 Ų046.7 Ų46.70%024%0.239CC..Hα-helixtrans-54.1-41.5172.3163.40000111.3L422 Y425 C426 L429 T445 L446 V451 V452 F453 M488L422-V449 HydrophobicContact CD1-CG1 3.98Å; L422-V449 HydrophobicContact CG-CG1 4.31Å; Y425-V449 HydrophobicContact CD1-CG2 3.8Å; Y425-V449 HydrophobicContact CE1-CG2 3.83Å; C426-V449 WeakPolarHBondContact SG-CG1 3.37Å; L429-V449 HydrophobicContact CD1-CG2 4.3Å; T445-V449 WeakPolarHBondContact O-CG2 3.3Å; T445-V449 PolarHBondContact O-N 2.94Å; L446-V449 WeakPolarHBondContact O-CB 3.49Å; L446-V449 PolarHBondContact O-N 3.3Å; V449-V451 VanDerWaalsContact C-N 3.28Å; V449-V451 PolarHBondContact O-N 3.41Å; V449-V452 PolarHBondContact O-N 2.86Å; V449-F453 PolarHBondContact O-N 3.45Å; V449-M488 HydrophobicContact CG1-CE 4.16Å
450M95.1Very high92.7Very high27 Ų2740.5 Ų40.513%0.13321%0.21CC..Hα-helixtrans-66.7-27.6178.9-68.4-56.2-58.500113.3L446 N447 Q448 F453 K454 M488 K491 L492 A495L446-M450 WeakPolarHBondContact O-CG 3.4Å; L446-M450 PolarHBondContact O-N 3.37Å; L446-M450 VanDerWaalsContact O-N 3.1Å; N447-M450 WeakPolarHBondContact O-CB 3.28Å; N447-M450 PolarHBondContact O-N 2.97Å; N447-M450 VanDerWaalsContact O-N 3.17Å; Q448-M450 PolarHBondContact O-N 3.03Å; M450-F453 HydrophobicContact CE-CB 4.36Å; M450-F453 HydrophobicContact CE-CD1 3.5Å; M450-F453 VanDerWaalsContact CE-CD1 3.5Å; M450-F453 HydrophobicContact CE-CE1 4.07Å; M450-F453 HydrophobicContact CE-CG 4.14Å; M450-F453 PolarHBondContact O-N 3.46Å; M450-F453 HydrophobicContact SD-CB 4.3Å; M450-F453 HydrophobicContact SD-CD1 4.3Å; M450-F453 HydrophobicContact SD-CG 4.38Å; M450-K454 PolarHBondContact O-N 2.97Å; M450-M488 HydrophobicContact SD-CE 3.71Å; M450-M488 HydrophobicContact SD-SD 4.28Å; M450-K491 HydrophobicContact CE-CB 4.27Å; M450-K491 HydrophobicContact CG-CB 4.01Å; M450-K491 HydrophobicContact CG-CD 3.98Å; M450-K491 HydrophobicContact SD-CB 4.15Å; M450-L492 HydrophobicContact CE-CD2 4.22Å; M450-L492 HydrophobicContact SD-CD2 4.08Å; M450-A495 HydrophobicContact CE-CB 3.85Å
451V94.1Very high92.8Very high50 Ų5037.3 Ų37.330%0.30318%0.183SC..Hα-helixtrans-62-47171177.60000110.4N447 Q448 V449 K454 Y455N447-V451 PolarHBondContact O-N 3.25Å; Q448-V451 VanDerWaalsContact O-CB 3.29Å; Q448-V451 WeakPolarHBondContact O-CB 3.5Å; Q448-V451 PolarHBondContact O-N 3Å; V449-V451 VanDerWaalsContact C-N 3.28Å; V449-V451 PolarHBondContact O-N 3.41Å; V451-K454 WeakPolarHBondContact O-CB 3.38Å; V451-K454 PolarHBondContact O-N 3.39Å; V451-Y455 HydrophobicContact CG1-CE2 4.2Å; V451-Y455 WeakPolarHBondContact O-CD2 3.49Å; V451-Y455 VanDerWaalsContact O-CE2 3.29Å; V451-Y455 WeakPolarHBondContact O-CE2 3.45Å
452V94.8Very high93Very high4 Ų431.9 Ų31.92%0.02416%0.158CC..Hα-helixtrans-66.6-41176-178.30000111V367 T370 L371 I403 L422 Q448 V449 K454 Y455V367-V452 HydrophobicContact CG1-CG2 4.49Å; T370-V452 HydrophobicContact CG2-CG1 4.04Å; T370-V452 HydrophobicContact CG2-CG2 4.05Å; L371-V452 HydrophobicContact CD2-CG2 3.56Å; L371-V452 HydrophobicContact CG-CG2 3.73Å; I403-V452 HydrophobicContact CD1-CG1 4.4Å; I403-V452 HydrophobicContact CG2-CG1 4.49Å; L422-V452 HydrophobicContact CD1-CB 4.21Å; L422-V452 HydrophobicContact CD1-CG1 4.16Å; L422-V452 HydrophobicContact CD2-CG1 4.31Å; Q448-V452 PolarHBondContact O-N 2.82Å; V449-V452 PolarHBondContact O-N 2.86Å; V452-K454 PolarHBondContact O-N 3.02Å; V452-Y455 PolarHBondContact O-N 2.99Å
453F94.9Very high93.1Very high1 Ų133 Ų330%0.00416%0.163CC..Hα-helixtrans-58-34.8178.8-178.5-98.9000113L422 V449 M450 Y455 I456 K459 F462 L492 A495 C496L422-F453 HydrophobicContact CD2-CB 3.98Å; L422-F453 HydrophobicContact CD2-CD2 4.23Å; V449-F453 PolarHBondContact O-N 3.45Å; M450-F453 HydrophobicContact CE-CB 4.36Å; M450-F453 HydrophobicContact CE-CD1 3.5Å; M450-F453 VanDerWaalsContact CE-CD1 3.5Å; M450-F453 HydrophobicContact CE-CE1 4.07Å; M450-F453 HydrophobicContact CE-CG 4.14Å; M450-F453 PolarHBondContact O-N 3.46Å; M450-F453 HydrophobicContact SD-CB 4.3Å; M450-F453 HydrophobicContact SD-CD1 4.3Å; M450-F453 HydrophobicContact SD-CG 4.38Å; F453-Y455 PolarHBondContact O-N 2.87Å; F453-I456 WeakPolarHBondContact O-CB 3.22Å; F453-I456 PolarHBondContact O-N 2.88Å; F453-I456 VanDerWaalsContact O-N 3.13Å; F453-K459 HydrophobicContact CE1-CD 4.14Å; F453-K459 HydrophobicContact CE2-CB 4.4Å; F453-K459 HydrophobicContact CE2-CG 4.25Å; F453-K459 HydrophobicContact CZ-CB 4.21Å; F453-K459 HydrophobicContact CZ-CD 3.95Å; F453-K459 HydrophobicContact CZ-CG 4.03Å; F453-F462 HydrophobicContact CD2-CD1 4.07Å; F453-F462 HydrophobicContact CD2-CD2 4.28Å; F453-F462 HydrophobicContact CD2-CE1 4.32Å; F453-F462 HydrophobicContact CD2-CE2 4.49Å; F453-F462 HydrophobicContact CD2-CG 4.06Å; F453-F462 HydrophobicContact CE2-CB 4.13Å; F453-F462 AromaticContact CE2-CD1 3.53Å; F453-F462 HydrophobicContact CE2-CD1 3.53Å; F453-F462 HydrophobicContact CE2-CD2 4.44Å; F453-F462 HydrophobicContact CE2-CE1 4.03Å; F453-F462 AromaticContact CE2-CG 3.78Å; F453-F462 HydrophobicContact CE2-CG 3.78Å; F453-F462 HydrophobicContact CZ-CD1 4.47Å; F453-L492 HydrophobicContact CE1-CD2 4.09Å; F453-L492 HydrophobicContact CE2-CD2 4.1Å; F453-L492 HydrophobicContact CZ-CD2 3.86Å; F453-A495 HydrophobicContact CD1-CB 4.35Å; F453-A495 HydrophobicContact CE1-CB 4Å; F453-C496 VanDerWaalsContact CE1-SG 3.55Å; F453-C496 VanDerWaalsContact CZ-SG 3.58Å
454K93.3Very high93Very high114 Ų11432.7 Ų32.750%0.49616%0.161SC..Hα-helixtrans-51.8-39.9175.2-178.2-169.5169.4-163.20111.7D396 M450 V451 V452D396-K454 IonicContact OD1-NZ 3.39Å; D396-K454 PolarHBondContact OD1-NZ 3.43Å; D396-K454 IonicContact OD2-NZ 2.7Å; D396-K454 PolarHBondContact OD2-NZ 2.96Å; M450-K454 PolarHBondContact O-N 2.97Å; V451-K454 WeakPolarHBondContact O-CB 3.38Å; V451-K454 PolarHBondContact O-N 3.39Å; V452-K454 PolarHBondContact O-N 3.02Å
455Y93.3Very high93Very high22 Ų2228.2 Ų28.29%0.08614%0.137CC..THydrogen-bonded Turntrans-86.8-6.8-174.9-58.4-63.9000114.3H374 D396 C399 I403 N404 V451 V452 F453 E457H374-Y455 AromaticContact CD2-CE2 3.69Å; H374-Y455 AromaticContact NE2-CE2 3.97Å; H374-Y455 PolarHBondContact NE2-OH 3.19Å; D396-Y455 HydrophobicContact CB-CE1 4.05Å; D396-Y455 WeakPolarHBondContact OD1-CE1 3.47Å; D396-Y455 VanDerWaalsContact OD1-CZ 3.27Å; D396-Y455 PolarHBondContact OD1-OH 3.3Å; C399-Y455 HydrophobicContact CB-CD1 3.76Å; C399-Y455 HydrophobicContact CB-CD2 3.96Å; C399-Y455 HydrophobicContact CB-CE1 3.81Å; C399-Y455 HydrophobicContact CB-CE2 3.99Å; C399-Y455 HydrophobicContact CB-CG 3.86Å; I403-Y455 HydrophobicContact CD1-CD2 3.79Å; I403-Y455 HydrophobicContact CD1-CG 3.95Å; N404-Y455 PolarHBondContact ND2-O 3.4Å; V451-Y455 HydrophobicContact CG1-CE2 4.2Å; V451-Y455 WeakPolarHBondContact O-CD2 3.49Å; V451-Y455 VanDerWaalsContact O-CE2 3.29Å; V451-Y455 WeakPolarHBondContact O-CE2 3.45Å; V452-Y455 PolarHBondContact O-N 2.99Å; F453-Y455 PolarHBondContact O-N 2.87Å; Y455-E457 PolarHBondContact O-N 3.24Å
456I92.1Very high93.1Very high4 Ų426.7 Ų26.72%0.02113%0.127CC..  trans-72.8126.7179-65.5-67.7000110.4I403 P419 L422 F453 K459I403-I456 HydrophobicContact CG2-CD1 3.69Å; P419-I456 HydrophobicContact CB-CG2 4.03Å; P419-I456 HydrophobicContact CG-CD1 4.34Å; P419-I456 HydrophobicContact CG-CG2 3.72Å; L422-I456 HydrophobicContact CD2-CG1 4.1Å; F453-I456 WeakPolarHBondContact O-CB 3.22Å; F453-I456 PolarHBondContact O-N 2.88Å; F453-I456 VanDerWaalsContact O-N 3.13Å; I456-K459 HydrophobicContact CB-CG 4.46Å; I456-K459 HydrophobicContact CG2-CG 4.17Å; I456-K459 VanDerWaalsContact O-CE 3.29Å; I456-K459 WeakPolarHBondContact O-CE 3.31Å; I456-K459 WeakPolarHBondContact O-CG 3.47Å
457E89.1Confident93.1Very high77 Ų7727.4 Ų27.436%0.3613%0.133SC..SBendtrans-76.8-49.6172.6-74.1-171.9159.400111.3N404 Y455 K459 F742 K743N404-E457 PolarHBondContact OD1-N 3.23Å; Y455-E457 PolarHBondContact O-N 3.24Å; E457-K459 VanDerWaalsContact C-N 3.34Å; E457-K459 PolarHBondContact O-N 3.32Å; E457-F742 WeakPolarHBondContact O-CA 3.32Å; E457-K743 IonicContact OE1-NZ 3.58Å; E457-K743 PolarHBondContact OE1-NZ 3.04Å; E457-K743 WeakPolarHBondContact OE2-CD 3.47Å; E457-K743 IonicContact OE2-NZ 2.9Å
458D90.1Very high92.9Very high7 Ų725.4 Ų25.44%0.03712%0.122CC..  trans-85.163.4-176.3-73.7-36.3000112.4S415 P419 D460 V461 R707S415-D458 PolarHBondContact OG-OD2 3.38Å; P419-D458 HydrophobicContact CG-CB 3.99Å; P419-D458 WeakPolarHBondContact CG-O 3.45Å; D458-D460 VanDerWaalsContact C-N 3.29Å; D458-D460 PolarHBondContact O-N 3.08Å; D458-V461 HydrophobicContact CB-CB 4.4Å; D458-V461 HydrophobicContact CB-CG2 3.91Å; D458-V461 WeakPolarHBondContact O-CB 3.48Å; D458-V461 PolarHBondContact O-N 3.38Å; D458-R707 IonicContact OD1-CZ 3Å; D458-R707 IonicContact OD1-NH1 3.73Å; D458-R707 IonicContact OD1-NH2 2.91Å; D458-R707 PolarHBondContact OD1-NH2 3.31Å; D458-R707 IonicContact OD2-NH2 3.73Å
459K92.6Very high92.8Very high38 Ų3823.9 Ų23.917%0.16512%0.115CC..Hα-helixtrans-67.7-26.3-176.5-64.1-179.5177.5132.60113.5F453 I456 E457 V461 F462 Q463 Y500 R741F453-K459 HydrophobicContact CE1-CD 4.14Å; F453-K459 HydrophobicContact CE2-CB 4.4Å; F453-K459 HydrophobicContact CE2-CG 4.25Å; F453-K459 HydrophobicContact CZ-CB 4.21Å; F453-K459 HydrophobicContact CZ-CD 3.95Å; F453-K459 HydrophobicContact CZ-CG 4.03Å; I456-K459 HydrophobicContact CB-CG 4.46Å; I456-K459 HydrophobicContact CG2-CG 4.17Å; I456-K459 VanDerWaalsContact O-CE 3.29Å; I456-K459 WeakPolarHBondContact O-CE 3.31Å; I456-K459 WeakPolarHBondContact O-CG 3.47Å; E457-K459 VanDerWaalsContact C-N 3.34Å; E457-K459 PolarHBondContact O-N 3.32Å; K459-V461 VanDerWaalsContact C-N 3.32Å; K459-F462 PolarHBondContact O-N 2.84Å; K459-Q463 PolarHBondContact O-N 2.72Å; K459-Y500 HydrophobicContact CB-CE2 4.29Å; K459-Y500 PolarHBondContact O-OH 2.92Å; K459-R741 WeakPolarHBondContact CA-O 3.5Å; K459-R741 WeakPolarHBondContact CB-O 3.34Å; K459-R741 PolarHBondContact N-O 3.36Å
460D91.1Very high92.8Very high15 Ų1523.9 Ų23.98%0.0812%0.115CC..Hα-helixtrans-63.5-3517465.1-27000112.8D458 Q463 K464 R707 R741 F742D458-D460 VanDerWaalsContact C-N 3.29Å; D458-D460 PolarHBondContact O-N 3.08Å; D460-Q463 WeakPolarHBondContact O-CB 3.44Å; D460-Q463 PolarHBondContact O-N 3.29Å; D460-K464 PolarHBondContact O-N 3.46Å; D460-R707 IonicContact OD1-CZ 2.77Å; D460-R707 IonicContact OD1-NE 3.83Å; D460-R707 IonicContact OD1-NH2 3.86Å; D460-R707 PolarHBondContact OD1-NH2 2.94Å; D460-R707 WeakPolarHBondContact OD2-CG 3.38Å; D460-R707 IonicContact OD2-CZ 2.68Å; D460-R707 IonicContact OD2-NE 3.76Å; D460-R707 PolarHBondContact OD2-NE 3.19Å; D460-R707 IonicContact OD2-NH2 2.81Å; D460-R707 PolarHBondContact OD2-NH2 3.44Å; D460-R741 PolarHBondContact N-O 3.27Å; D460-F742 WeakPolarHBondContact OD1-CB 3.44Å
461V92.7Very high92.7Very high0 Ų022.6 Ų22.60%011%0.109CC..Hα-helixtrans-61.5-50.9173.21770000109.7P419 D458 K459 Q463 K464 F465 I703P419-V461 HydrophobicContact CB-CB 3.98Å; P419-V461 HydrophobicContact CB-CG1 3.99Å; P419-V461 HydrophobicContact CG-CB 4.25Å; P419-V461 HydrophobicContact CG-CG1 4.39Å; D458-V461 HydrophobicContact CB-CB 4.4Å; D458-V461 HydrophobicContact CB-CG2 3.91Å; D458-V461 WeakPolarHBondContact O-CB 3.48Å; D458-V461 PolarHBondContact O-N 3.38Å; K459-V461 VanDerWaalsContact C-N 3.32Å; V461-Q463 VanDerWaalsContact C-N 3.27Å; V461-Q463 PolarHBondContact O-N 3.48Å; V461-K464 PolarHBondContact O-N 2.93Å; V461-F465 HydrophobicContact CG1-CD2 3.75Å; V461-F465 HydrophobicContact CG1-CE2 3.86Å; V461-F465 WeakPolarHBondContact O-CD2 3.4Å; V461-F465 PolarHBondContact O-N 3.39Å; V461-F465 VanDerWaalsContact O-N 3.1Å; V461-I703 HydrophobicContact CB-CD1 4.43Å; V461-I703 HydrophobicContact CG1-CD1 4.28Å; V461-I703 HydrophobicContact CG2-CD1 4.34Å; V461-I703 HydrophobicContact CG2-CG2 4.13Å
462F94.6Very high92.5Very high0 Ų023.4 Ų23.40%011%0.108CC..Hα-helixtrans-54.6-47.1174.7177-85.4000110.6P419 L422 A423 F453 K459 K464 F465 Y466 M488 L492P419-F462 HydrophobicContact CB-CB 4Å; L422-F462 HydrophobicContact CB-CD2 4.14Å; L422-F462 HydrophobicContact CB-CE2 4.26Å; L422-F462 HydrophobicContact CD2-CD2 4.14Å; L422-F462 HydrophobicContact CD2-CE2 4.16Å; L422-F462 HydrophobicContact CG-CD2 4.16Å; L422-F462 HydrophobicContact CG-CE2 3.93Å; A423-F462 HydrophobicContact CB-CD2 3.73Å; A423-F462 HydrophobicContact CB-CE2 3.9Å; A423-F462 HydrophobicContact CB-CG 4.39Å; F453-F462 HydrophobicContact CD2-CD1 4.07Å; F453-F462 HydrophobicContact CD2-CD2 4.28Å; F453-F462 HydrophobicContact CD2-CE1 4.32Å; F453-F462 HydrophobicContact CD2-CE2 4.49Å; F453-F462 HydrophobicContact CD2-CG 4.06Å; F453-F462 HydrophobicContact CE2-CB 4.13Å; F453-F462 AromaticContact CE2-CD1 3.53Å; F453-F462 HydrophobicContact CE2-CD1 3.53Å; F453-F462 HydrophobicContact CE2-CD2 4.44Å; F453-F462 HydrophobicContact CE2-CE1 4.03Å; F453-F462 AromaticContact CE2-CG 3.78Å; F453-F462 HydrophobicContact CE2-CG 3.78Å; F453-F462 HydrophobicContact CZ-CD1 4.47Å; K459-F462 PolarHBondContact O-N 2.84Å; F462-K464 PolarHBondContact O-N 3.12Å; F462-F465 PolarHBondContact O-N 3.27Å; F462-Y466 AromaticContact CE1-CD2 3.98Å; F462-Y466 HydrophobicContact CE1-CD2 3.98Å; F462-Y466 HydrophobicContact CE1-CG 4.01Å; F462-Y466 AromaticContact CZ-CD2 3.76Å; F462-Y466 HydrophobicContact CZ-CD2 3.76Å; F462-Y466 HydrophobicContact CZ-CE2 4.46Å; F462-Y466 HydrophobicContact CZ-CG 4.26Å; F462-Y466 WeakPolarHBondContact O-CB 3.37Å; F462-Y466 PolarHBondContact O-N 3.32Å; F462-M488 HydrophobicContact CZ-CE 4.11Å; F462-L492 HydrophobicContact CD1-CD2 4.39Å; F462-L492 HydrophobicContact CE1-CD1 4.06Å; F462-L492 HydrophobicContact CE1-CD2 3.7Å; F462-L492 HydrophobicContact CZ-CD2 4.42Å
463Q93.1Very high92.3Very high32 Ų3223.5 Ų23.515%0.1511%0.108CC..Hα-helixtrans-55.4-48179.9-159.8-168.5-7.800112.1K459 D460 V461 A467 Y500K459-Q463 PolarHBondContact O-N 2.72Å; D460-Q463 WeakPolarHBondContact O-CB 3.44Å; D460-Q463 PolarHBondContact O-N 3.29Å; V461-Q463 VanDerWaalsContact C-N 3.27Å; V461-Q463 PolarHBondContact O-N 3.48Å; Q463-A467 WeakPolarHBondContact O-CB 3.15Å; Q463-A467 PolarHBondContact O-N 2.97Å; Q463-Y500 HydrophobicContact CB-CE1 4.19Å; Q463-Y500 HydrophobicContact CB-CE2 3.67Å; Q463-Y500 VanDerWaalsContact CB-CZ 3.47Å; Q463-Y500 VanDerWaalsContact CB-OH 3.31Å; Q463-Y500 WeakPolarHBondContact CB-OH 3.33Å; Q463-Y500 HydrophobicContact CG-CD1 4.27Å; Q463-Y500 HydrophobicContact CG-CD2 4.19Å; Q463-Y500 HydrophobicContact CG-CE1 3.84Å; Q463-Y500 HydrophobicContact CG-CE2 3.75Å; Q463-Y500 HydrophobicContact CG-CG 4.44Å; Q463-Y500 PolarHBondContact N-OH 2.95Å; Q463-Y500 PolarHBondContact NE2-O 3.47Å
464K91.4Very high92.2Very high49 Ų4923.9 Ų23.921%0.21311%0.11CC..Hα-helixtrans-68.3-43.9-175.4-120.5-73.3-167.8177.30111.6D460 V461 F462 K468 T699 I703D460-K464 PolarHBondContact O-N 3.46Å; V461-K464 PolarHBondContact O-N 2.93Å; F462-K464 PolarHBondContact O-N 3.12Å; K464-K468 WeakPolarHBondContact O-CB 3.43Å; K464-K468 PolarHBondContact O-N 3.02Å; K464-K468 VanDerWaalsContact O-N 3.13Å; K464-T699 HydrophobicContact CB-CG2 4.45Å; K464-T699 HydrophobicContact CD-CG2 4.23Å; K464-I703 HydrophobicContact CB-CD1 3.86Å; K464-I703 HydrophobicContact CB-CG1 3.79Å; K464-I703 HydrophobicContact CG-CD1 4.37Å; K464-I703 HydrophobicContact CG-CG1 3.77Å
465F92.4Very high92Very high2 Ų219.2 Ų19.21%0.0099%0.091CC..Hα-helixtrans-66.4-45.4175.6-82.1-76.2000111.6E420 A423 V461 F462 K468 M469 Q696 T699 H700 I703E420-F465 HydrophobicContact CB-CD2 4.18Å; E420-F465 HydrophobicContact CB-CE2 4.19Å; E420-F465 HydrophobicContact CG-CD1 3.99Å; E420-F465 HydrophobicContact CG-CD2 3.99Å; E420-F465 HydrophobicContact CG-CE1 3.87Å; E420-F465 HydrophobicContact CG-CE2 3.89Å; E420-F465 HydrophobicContact CG-CG 4.06Å; E420-F465 HydrophobicContact CG-CZ 3.84Å; A423-F465 HydrophobicContact CB-CB 3.78Å; V461-F465 HydrophobicContact CG1-CD2 3.75Å; V461-F465 HydrophobicContact CG1-CE2 3.86Å; V461-F465 WeakPolarHBondContact O-CD2 3.4Å; V461-F465 PolarHBondContact O-N 3.39Å; V461-F465 VanDerWaalsContact O-N 3.1Å; F462-F465 PolarHBondContact O-N 3.27Å; F465-K468 PolarHBondContact O-N 3.42Å; F465-M469 WeakPolarHBondContact O-CB 3.42Å; F465-M469 WeakPolarHBondContact O-CG 3.48Å; F465-M469 PolarHBondContact O-N 3.19Å; F465-Q696 HydrophobicContact CE1-CG 4.2Å; F465-Q696 HydrophobicContact CZ-CG 4.29Å; F465-T699 HydrophobicContact CD1-CG2 4.23Å; F465-T699 HydrophobicContact CD2-CG2 4.36Å; F465-T699 HydrophobicContact CE1-CG2 3.93Å; F465-T699 HydrophobicContact CE2-CG2 4.05Å; F465-T699 HydrophobicContact CG-CG2 4.43Å; F465-T699 HydrophobicContact CZ-CG2 3.81Å; F465-H700 AromaticContact CE2-CE1 3.64Å; F465-H700 AromaticContact CE2-NE2 3.77Å; F465-H700 AromaticContact CZ-CD2 3.83Å; F465-H700 AromaticContact CZ-CE1 3.8Å; F465-H700 AromaticContact CZ-NE2 3.43Å; F465-H700 WeakPolarHBondContact CZ-NE2 3.34Å; F465-I703 HydrophobicContact CD2-CD1 4.44Å; F465-I703 HydrophobicContact CE2-CD1 4.09Å
466Y94.5Very high91.7Very high0 Ų021.3 Ų21.30%010%0.101CC..Hα-helixtrans-61-46.9176.9-172.4-87.8000111.6C426 L430 F462 K468 M469 L470 E485 M488 L492 L504C426-Y466 HydrophobicContact CB-CD2 4.22Å; C426-Y466 HydrophobicContact CB-CE2 4.03Å; L430-Y466 HydrophobicContact CD1-CE2 4.22Å; L430-Y466 WeakPolarHBondContact CD1-OH 3.45Å; F462-Y466 AromaticContact CE1-CD2 3.98Å; F462-Y466 HydrophobicContact CE1-CD2 3.98Å; F462-Y466 HydrophobicContact CE1-CG 4.01Å; F462-Y466 AromaticContact CZ-CD2 3.76Å; F462-Y466 HydrophobicContact CZ-CD2 3.76Å; F462-Y466 HydrophobicContact CZ-CE2 4.46Å; F462-Y466 HydrophobicContact CZ-CG 4.26Å; F462-Y466 WeakPolarHBondContact O-CB 3.37Å; F462-Y466 PolarHBondContact O-N 3.32Å; Y466-K468 VanDerWaalsContact C-N 3.31Å; Y466-K468 PolarHBondContact O-N 3.49Å; Y466-M469 PolarHBondContact O-N 3.36Å; Y466-L470 HydrophobicContact CD1-CB 4.48Å; Y466-L470 HydrophobicContact CE1-CB 4.3Å; Y466-L470 HydrophobicContact CE1-CD2 4.17Å; Y466-L470 VanDerWaalsContact O-CB 3.27Å; Y466-L470 WeakPolarHBondContact O-CB 3.19Å; Y466-L470 PolarHBondContact O-N 2.89Å; Y466-E485 PolarHBondContact OH-OE2 2.98Å; Y466-M488 HydrophobicContact CE2-CG 4.12Å; Y466-M488 VanDerWaalsContact OH-CG 3.28Å; Y466-M488 WeakPolarHBondContact OH-CG 3.41Å; Y466-L492 HydrophobicContact CD1-CD1 4.3Å; Y466-L492 HydrophobicContact CE1-CD1 4.16Å; Y466-L504 HydrophobicContact CD1-CD1 4Å; Y466-L504 HydrophobicContact CD1-CD2 4.31Å; Y466-L504 HydrophobicContact CE1-CD1 4.15Å
467A93.3Very high91.4Very high15 Ų1527.7 Ų27.712%0.12413%0.131CC..Hα-helixtrans-59-41.917800000112Q463 A471 L504 M507Q463-A467 WeakPolarHBondContact O-CB 3.15Å; Q463-A467 PolarHBondContact O-N 2.97Å; A467-A471 VanDerWaalsContact O-CB 3.24Å; A467-A471 WeakPolarHBondContact O-CB 3.25Å; A467-A471 PolarHBondContact O-N 2.84Å; A467-L504 HydrophobicContact CB-CD2 3.59Å; A467-M507 HydrophobicContact CB-CE 4.17Å
468K90.8Very high91.4Very high22 Ų2226.4 Ų26.410%0.09613%0.127CC..Hα-helixtrans-65.4-44.4177.1-175.5170.9114.3173.70112.4K464 F465 Y466 A471 K472 P546 E695 T699K464-K468 WeakPolarHBondContact O-CB 3.43Å; K464-K468 PolarHBondContact O-N 3.02Å; K464-K468 VanDerWaalsContact O-N 3.13Å; F465-K468 PolarHBondContact O-N 3.42Å; Y466-K468 VanDerWaalsContact C-N 3.31Å; Y466-K468 PolarHBondContact O-N 3.49Å; K468-A471 PolarHBondContact O-N 2.88Å; K468-K472 WeakPolarHBondContact O-CG 3.15Å; K468-K472 PolarHBondContact O-N 2.67Å; K468-K472 VanDerWaalsContact O-N 3.1Å; K468-P546 HydrophobicContact CB-CG 4.31Å; K468-E695 HydrophobicContact CD-CG 4.41Å; K468-E695 VanDerWaalsContact CD-OE1 3.23Å; K468-E695 WeakPolarHBondContact CD-OE1 3.43Å; K468-E695 WeakPolarHBondContact CE-OE1 3.33Å; K468-E695 PolarHBondContact NZ-O 2.82Å; K468-E695 IonicContact NZ-OE1 3.62Å; K468-E695 PolarHBondContact NZ-OE1 2.75Å; K468-E695 VanDerWaalsContact NZ-OE1 3.17Å; K468-E695 IonicContact NZ-OE2 2.97Å; K468-E695 PolarHBondContact NZ-OE2 3.25Å; K468-T699 PolarHBondContact NZ-OG1 2.93Å
469M92Very high91.4Very high23 Ų2326.8 Ų26.811%0.11313%0.13CC..Hα-helixtrans-67-44.6178.1-75170.7173.600111.6R424 D427 F465 Y466 A471 K472 R473R424-M469 HydrophobicContact CB-CE 4.38Å; R424-M469 HydrophobicContact CG-CE 3.45Å; R424-M469 VanDerWaalsContact CG-CE 3.45Å; R424-M469 HydrophobicContact CG-SD 4.33Å; D427-M469 HydrophobicContact CB-CB 4.05Å; D427-M469 HydrophobicContact CB-CG 4.17Å; D427-M469 HydrophobicContact CB-SD 3.58Å; D427-M469 VanDerWaalsContact CB-SD 3.58Å; D427-M469 WeakPolarHBondContact OD1-CB 3.31Å; F465-M469 WeakPolarHBondContact O-CB 3.42Å; F465-M469 WeakPolarHBondContact O-CG 3.48Å; F465-M469 PolarHBondContact O-N 3.19Å; Y466-M469 PolarHBondContact O-N 3.36Å; M469-A471 PolarHBondContact O-N 3.04Å; M469-K472 PolarHBondContact O-N 3.13Å; M469-R473 WeakPolarHBondContact O-CG 3.38Å; M469-R473 PolarHBondContact O-N 2.76Å
470L93.9Very high91.2Very high0 Ų026.7 Ų26.70%014%0.136CC..Hα-helixtrans-57.6-47.8173.2176.362.8000111.2Y466 K472 R473 L474 E485 I489 L504 M507 F508Y466-L470 HydrophobicContact CD1-CB 4.48Å; Y466-L470 HydrophobicContact CE1-CB 4.3Å; Y466-L470 HydrophobicContact CE1-CD2 4.17Å; Y466-L470 VanDerWaalsContact O-CB 3.27Å; Y466-L470 WeakPolarHBondContact O-CB 3.19Å; Y466-L470 PolarHBondContact O-N 2.89Å; L470-K472 VanDerWaalsContact C-N 3.27Å; L470-K472 PolarHBondContact O-N 2.88Å; L470-R473 PolarHBondContact O-N 3.22Å; L470-R473 VanDerWaalsContact O-N 3.08Å; L470-L474 HydrophobicContact CD1-CD1 3.94Å; L470-L474 HydrophobicContact CD1-CD2 4.29Å; L470-L474 HydrophobicContact CD1-CG 3.81Å; L470-L474 HydrophobicContact CD2-CD1 4.43Å; L470-L474 HydrophobicContact CG-CD1 3.87Å; L470-L474 HydrophobicContact CG-CG 4.15Å; L470-L474 WeakPolarHBondContact O-CB 3.42Å; L470-L474 WeakPolarHBondContact O-CG 3.45Å; L470-L474 PolarHBondContact O-N 2.95Å; L470-E485 WeakPolarHBondContact CD1-OE2 3.43Å; L470-I489 HydrophobicContact CD2-CD1 4.07Å; L470-L504 HydrophobicContact CD2-CB 4.15Å; L470-L504 HydrophobicContact CD2-CD2 4.1Å; L470-M507 HydrophobicContact CD2-CE 3.99Å; L470-F508 HydrophobicContact CD1-CE2 3.71Å; L470-F508 HydrophobicContact CD1-CZ 4.18Å; L470-F508 HydrophobicContact CD2-CD2 4.41Å; L470-F508 HydrophobicContact CD2-CE2 4.04Å; L470-F508 HydrophobicContact CG-CE2 4.41Å
471A92.4Very high91.2Very high0 Ų027.1 Ų27.10%014%0.14CC..Hα-helixtrans-55.7-43.8177.400000111.8A467 K468 M469 V475 M507 W545 P546 F547A467-A471 VanDerWaalsContact O-CB 3.24Å; A467-A471 WeakPolarHBondContact O-CB 3.25Å; A467-A471 PolarHBondContact O-N 2.84Å; K468-A471 PolarHBondContact O-N 2.88Å; M469-A471 PolarHBondContact O-N 3.04Å; A471-V475 WeakPolarHBondContact O-CB 3.49Å; A471-V475 WeakPolarHBondContact O-CG2 3.45Å; A471-V475 PolarHBondContact O-N 3.27Å; A471-M507 HydrophobicContact CB-SD 3.93Å; A471-W545 HydrophobicContact CB-CE3 3.7Å; A471-W545 HydrophobicContact CB-CZ3 3.83Å; A471-P546 HydrophobicContact CB-CG 3.68Å; A471-F547 HydrophobicContact CB-CE1 4.04Å; A471-F547 HydrophobicContact CB-CE2 4.3Å; A471-F547 HydrophobicContact CB-CZ 3.66Å
472K89.3Confident91Very high66 Ų6631.5 Ų31.529%0.28716%0.164SC..Hα-helixtrans-64.3-45.6174.4-70.1-174.6-177.4-167.70111.9K468 M469 L470 L474 V475 H476 E695K468-K472 WeakPolarHBondContact O-CG 3.15Å; K468-K472 PolarHBondContact O-N 2.67Å; K468-K472 VanDerWaalsContact O-N 3.1Å; M469-K472 PolarHBondContact O-N 3.13Å; L470-K472 VanDerWaalsContact C-N 3.27Å; L470-K472 PolarHBondContact O-N 2.88Å; K472-L474 VanDerWaalsContact C-N 3.35Å; K472-L474 PolarHBondContact O-N 2.78Å; K472-V475 PolarHBondContact O-N 2.8Å; K472-H476 WeakPolarHBondContact O-CB 3.37Å; K472-H476 PolarHBondContact O-N 2.63Å; K472-H476 PolarHBondContact O-ND1 2.91Å; K472-E695 WeakPolarHBondContact CE-OE1 3.32Å; K472-E695 IonicContact NZ-OE1 2.84Å; K472-E695 PolarHBondContact NZ-OE1 3.29Å; K472-E695 IonicContact NZ-OE2 3.69Å; K472-E695 PolarHBondContact NZ-OE2 3.03Å
473R92.1Very high90.9Very high6 Ų637.4 Ų37.42%0.02320%0.195CC..Hα-helixtrans-61.3-43.1179.3-68.5-167.9-54.1-91.56.1112D427 M469 L470 Q477 N478 E485D427-R473 WeakPolarHBondContact OD1-CD 3.09Å; D427-R473 IonicContact OD1-CZ 3.17Å; D427-R473 IonicContact OD1-NE 3.43Å; D427-R473 IonicContact OD1-NH1 3.6Å; D427-R473 PolarHBondContact OD1-NH1 2.92Å; M469-R473 WeakPolarHBondContact O-CG 3.38Å; M469-R473 PolarHBondContact O-N 2.76Å; L470-R473 PolarHBondContact O-N 3.22Å; L470-R473 VanDerWaalsContact O-N 3.08Å; R473-Q477 WeakPolarHBondContact O-CA 3.43Å; R473-Q477 PolarHBondContact O-N 3.36Å; R473-N478 PolarHBondContact O-N 2.71Å; R473-E485 IonicContact CZ-OE1 3.73Å; R473-E485 IonicContact CZ-OE2 3.6Å; R473-E485 IonicContact NE-OE1 3.35Å; R473-E485 PolarHBondContact NE-OE1 2.74Å; R473-E485 IonicContact NE-OE2 3.62Å; R473-E485 IonicContact NH2-OE1 2.68Å; R473-E485 PolarHBondContact NH2-OE1 3.48Å; R473-E485 IonicContact NH2-OE2 3.12Å; R473-E485 PolarHBondContact NH2-OE2 3.41Å
474L92Very high90.9Very high9 Ų936.4 Ų36.45%0.04719%0.193CC..Hα-helixtrans-64.3-48.2177.9-71.7-179.6000112.6L470 K472 H476 Q477 M507 F508 I511 W545L470-L474 HydrophobicContact CD1-CD1 3.94Å; L470-L474 HydrophobicContact CD1-CD2 4.29Å; L470-L474 HydrophobicContact CD1-CG 3.81Å; L470-L474 HydrophobicContact CD2-CD1 4.43Å; L470-L474 HydrophobicContact CG-CD1 3.87Å; L470-L474 HydrophobicContact CG-CG 4.15Å; L470-L474 WeakPolarHBondContact O-CB 3.42Å; L470-L474 WeakPolarHBondContact O-CG 3.45Å; L470-L474 PolarHBondContact O-N 2.95Å; K472-L474 VanDerWaalsContact C-N 3.35Å; K472-L474 PolarHBondContact O-N 2.78Å; L474-H476 PolarHBondContact O-N 3.46Å; L474-Q477 PolarHBondContact O-N 3.27Å; L474-M507 HydrophobicContact CD1-CB 3.87Å; L474-F508 HydrophobicContact CD1-CD2 4.28Å; L474-F508 HydrophobicContact CD1-CE2 4.27Å; L474-F508 HydrophobicContact CD2-CD1 4.4Å; L474-F508 HydrophobicContact CD2-CE1 3.88Å; L474-F508 HydrophobicContact CD2-CE2 4.17Å; L474-F508 HydrophobicContact CD2-CZ 3.71Å; L474-I511 HydrophobicContact CB-CD1 4.23Å; L474-I511 HydrophobicContact CB-CG1 4.03Å; L474-I511 HydrophobicContact CD1-CG1 4.32Å; L474-I511 HydrophobicContact CD2-CG1 4.44Å; L474-W545 HydrophobicContact CB-CH2 3.96Å; L474-W545 HydrophobicContact CB-CZ3 4.36Å; L474-W545 HydrophobicContact CD1-CH2 4.04Å
475V89.6Confident90.9Very high17 Ų1734 Ų3410%0.10318%0.182CC..Hα-helixtrans-62.7-44.3178.6168.50000111.2A471 K472 Q477 Q538 L540 W545 F547A471-V475 WeakPolarHBondContact O-CB 3.49Å; A471-V475 WeakPolarHBondContact O-CG2 3.45Å; A471-V475 PolarHBondContact O-N 3.27Å; K472-V475 PolarHBondContact O-N 2.8Å; V475-Q477 VanDerWaalsContact C-N 3.25Å; V475-Q477 PolarHBondContact O-N 2.97Å; V475-Q538 PolarHBondContact O-NE2 3.05Å; V475-L540 HydrophobicContact CG2-CD1 3.98Å; V475-W545 HydrophobicContact CG2-CH2 4.33Å; V475-W545 HydrophobicContact CG2-CZ3 3.76Å; V475-F547 HydrophobicContact CG2-CE2 3.67Å; V475-F547 HydrophobicContact CG2-CZ 3.76Å
476H86.6Confident91Very high65 Ų6536.4 Ų36.430%0.30120%0.202SC..Hα-helixtrans-80.5-5-177.7-63.689.4000113.7K472 L474 N478 K587K472-H476 WeakPolarHBondContact O-CB 3.37Å; K472-H476 PolarHBondContact O-N 2.63Å; K472-H476 PolarHBondContact O-ND1 2.91Å; L474-H476 PolarHBondContact O-N 3.46Å; H476-N478 VanDerWaalsContact C-N 3.28Å; H476-N478 HydrophobicContact CB-CB 4.22Å; H476-N478 PolarHBondContact O-N 3.03Å; H476-K587 PolarHBondContact O-NZ 2.64Å
477Q86.6Confident91Very high138 Ų13837.8 Ų37.865%0.64521%0.212SC*.THydrogen-bonded Turntrans51.946.6-172.8-58.6178.410.700112R473 L474 V475R473-Q477 WeakPolarHBondContact O-CA 3.43Å; R473-Q477 PolarHBondContact O-N 3.36Å; L474-Q477 PolarHBondContact O-N 3.27Å; V475-Q477 VanDerWaalsContact C-N 3.25Å; V475-Q477 PolarHBondContact O-N 2.97Å
478N88.1Confident91Very high50 Ų5037 Ų3727%0.26721%0.206SC..  trans-117.423.3-172.8-164.146.6000112.8K431 K432 R473 H476K431-N478 WeakPolarHBondContact CA-O 3.49Å; K431-N478 WeakPolarHBondContact CE-ND2 3.44Å; K431-N478 WeakPolarHBondContact CG-ND2 3.31Å; K432-N478 PolarHBondContact N-O 3.37Å; R473-N478 PolarHBondContact O-N 2.71Å; H476-N478 VanDerWaalsContact C-N 3.28Å; H476-N478 HydrophobicContact CB-CB 4.22Å; H476-N478 PolarHBondContact O-N 3.03Å
479S90.3Very high91.2Very high16 Ų1636.3 Ų36.311%0.11220%0.203CC..BIsolated β-bridgetrans-75.8147.3170.6-66.60000110.6L430 E485L430-S479 CarbonylContact O-C 3.52Å; L430-S479 WeakPolarHBondContact O-CA 3.23Å; S479-E485 WeakPolarHBondContact CB-OE1 3.37Å; S479-E485 PolarHBondContact OG-OE1 3.38Å
480A89.3Confident91.4Very high35 Ų3537.9 Ų37.929%0.28922%0.216SC..SBendtrans-66.7-48.3177.200000111.5L430 N436L430-A480 WeakPolarHBondContact O-CB 3.49Å; L430-A480 PolarHBondContact O-N 3.09Å; N436-A480 WeakPolarHBondContact ND2-CB 3.29Å
481S90.3Very high91.4Very high24 Ų2439.4 Ų39.417%0.16822%0.223CC..  trans-153.4137.7178.2169.20000108.8D483 A484 E485S481-D483 VanDerWaalsContact C-N 3.28Å; S481-D483 PolarHBondContact OG-N 3.01Å; S481-A484 PolarHBondContact OG-N 3.49Å; S481-E485 WeakPolarHBondContact O-CG 3.36Å; S481-E485 PolarHBondContact O-N 2.94Å
482D89.5Confident91.5Very high92 Ų9239.5 Ų39.549%0.49222%0.223SC..Hα-helixtrans-66.9-33.5175.6-72.6-10.8000110.6E485 A486D482-E485 PolarHBondContact O-N 3.43Å; D482-A486 WeakPolarHBondContact O-CB 3.42Å; D482-A486 PolarHBondContact O-N 2.91Å
483D91.4Very high91.7Very high124 Ų12440.4 Ų40.466%0.66323%0.227SC*.Hα-helixtrans-69.7-40.4178.5-68.2-27.9000111.8S481 E485 A486 S487S481-D483 VanDerWaalsContact C-N 3.28Å; S481-D483 PolarHBondContact OG-N 3.01Å; D483-E485 VanDerWaalsContact C-N 3.32Å; D483-E485 PolarHBondContact O-N 3.06Å; D483-A486 PolarHBondContact O-N 3.26Å; D483-S487 WeakPolarHBondContact O-CB 3.38Å; D483-S487 PolarHBondContact O-N 2.86Å
484A92.3Very high91.6Very high11 Ų1147.8 Ų47.89%0.09126%0.262CS..Hα-helixtrans-63.7-38.3176.100000111.9L430 L442 S481 S487 M488L430-A484 HydrophobicContact CD2-CB 3.9Å; L442-A484 HydrophobicContact CD2-CB 3.93Å; S481-A484 PolarHBondContact OG-N 3.49Å; A484-S487 PolarHBondContact O-N 3.44Å; A484-M488 PolarHBondContact O-N 3.08Å
485E93.1Very high91.5Very high0 Ų050 Ų500%028%0.282CS..Hα-helixtrans-68.2-41.8175.8-63.7-91.2-156.900111.8Y466 L470 R473 S479 S481 D482 D483 M488 I489 F508Y466-E485 PolarHBondContact OH-OE2 2.98Å; L470-E485 WeakPolarHBondContact CD1-OE2 3.43Å; R473-E485 IonicContact CZ-OE1 3.73Å; R473-E485 IonicContact CZ-OE2 3.6Å; R473-E485 IonicContact NE-OE1 3.35Å; R473-E485 PolarHBondContact NE-OE1 2.74Å; R473-E485 IonicContact NE-OE2 3.62Å; R473-E485 IonicContact NH2-OE1 2.68Å; R473-E485 PolarHBondContact NH2-OE1 3.48Å; R473-E485 IonicContact NH2-OE2 3.12Å; R473-E485 PolarHBondContact NH2-OE2 3.41Å; S479-E485 WeakPolarHBondContact CB-OE1 3.37Å; S479-E485 PolarHBondContact OG-OE1 3.38Å; S481-E485 WeakPolarHBondContact O-CG 3.36Å; S481-E485 PolarHBondContact O-N 2.94Å; D482-E485 PolarHBondContact O-N 3.43Å; D483-E485 VanDerWaalsContact C-N 3.32Å; D483-E485 PolarHBondContact O-N 3.06Å; E485-M488 PolarHBondContact O-N 2.98Å; E485-I489 WeakPolarHBondContact O-CG1 3.39Å; E485-I489 PolarHBondContact O-N 3.31Å; E485-F508 HydrophobicContact CB-CE1 4.18Å; E485-F508 HydrophobicContact CB-CE2 3.89Å; E485-F508 HydrophobicContact CB-CZ 3.26Å; E485-F508 HydrophobicContact CG-CZ 3.99Å
486A93.1Very high91.4Very high51 Ų5150.6 Ų50.642%0.42129%0.286SS..Hα-helixtrans-63-41.9174.800000111.7D482 D483 I489 S490D482-A486 WeakPolarHBondContact O-CB 3.42Å; D482-A486 PolarHBondContact O-N 2.91Å; D483-A486 PolarHBondContact O-N 3.26Å; A486-I489 PolarHBondContact O-N 3.08Å; A486-S490 WeakPolarHBondContact O-CB 3.44Å; A486-S490 PolarHBondContact O-N 2.95Å
487S94.4Very high91.5Very high29 Ų2949 Ų4920%0.20329%0.288CS..Hα-helixtrans-57-50.8173.4178.20000110.9E443 D483 A484 I489 S490 K491E443-S487 PolarHBondContact OE1-OG 3.48Å; E443-S487 VanDerWaalsContact OE1-OG 3.11Å; E443-S487 PolarHBondContact OE2-OG 3.47Å; D483-S487 WeakPolarHBondContact O-CB 3.38Å; D483-S487 PolarHBondContact O-N 2.86Å; A484-S487 PolarHBondContact O-N 3.44Å; S487-I489 PolarHBondContact O-N 3.41Å; S487-S490 WeakPolarHBondContact O-CA 3.44Å; S487-S490 VanDerWaalsContact O-CB 3.3Å; S487-S490 WeakPolarHBondContact O-CB 3.34Å; S487-S490 PolarHBondContact O-N 3.15Å; S487-K491 WeakPolarHBondContact O-CG 3.23Å; S487-K491 PolarHBondContact O-N 3.36Å; S487-K491 WeakPolarHBondContact OG-CE 3.37Å
488M95.1Very high91.6Very high0 Ų048.4 Ų48.40%028%0.283CS..Hα-helixtrans-60.7-42.3179.5-172.559.7-17200112.4L430 L446 V449 M450 F462 Y466 A484 E485 S490 K491 L492L430-M488 HydrophobicContact CD1-CB 4.32Å; L430-M488 HydrophobicContact CD1-CG 4.27Å; L446-M488 HydrophobicContact CB-SD 4.49Å; L446-M488 HydrophobicContact CD2-SD 4.03Å; V449-M488 HydrophobicContact CG1-CE 4.16Å; M450-M488 HydrophobicContact SD-CE 3.71Å; M450-M488 HydrophobicContact SD-SD 4.28Å; F462-M488 HydrophobicContact CZ-CE 4.11Å; Y466-M488 HydrophobicContact CE2-CG 4.12Å; Y466-M488 VanDerWaalsContact OH-CG 3.28Å; Y466-M488 WeakPolarHBondContact OH-CG 3.41Å; A484-M488 PolarHBondContact O-N 3.08Å; E485-M488 PolarHBondContact O-N 2.98Å; M488-S490 VanDerWaalsContact C-N 3.31Å; M488-S490 PolarHBondContact O-N 3.42Å; M488-K491 PolarHBondContact O-N 3Å; M488-L492 HydrophobicContact CE-CD1 4.37Å; M488-L492 HydrophobicContact CE-CD2 4.18Å; M488-L492 HydrophobicContact CE-CG 4.19Å; M488-L492 WeakPolarHBondContact O-CG 3.23Å; M488-L492 PolarHBondContact O-N 3.06Å
489I94.2Very high91.5Very high6 Ų652.7 Ų52.73%0.03130%0.301CS..Hα-helixtrans-63.4-38.7175.2-67.6170.5000111.1L470 E485 A486 S487 L492 K493 T501 L504 Q505 F508L470-I489 HydrophobicContact CD2-CD1 4.07Å; E485-I489 WeakPolarHBondContact O-CG1 3.39Å; E485-I489 PolarHBondContact O-N 3.31Å; A486-I489 PolarHBondContact O-N 3.08Å; S487-I489 PolarHBondContact O-N 3.41Å; I489-L492 PolarHBondContact O-N 3.43Å; I489-K493 WeakPolarHBondContact O-CB 3.14Å; I489-K493 PolarHBondContact O-N 2.88Å; I489-T501 HydrophobicContact CG2-CG2 4.33Å; I489-L504 HydrophobicContact CD1-CB 3.99Å; I489-L504 HydrophobicContact CG1-CB 4.2Å; I489-L504 HydrophobicContact CG1-CD1 4.41Å; I489-L504 HydrophobicContact CG2-CB 4.45Å; I489-Q505 HydrophobicContact CG2-CG 3.66Å; I489-F508 HydrophobicContact CD1-CD2 3.35Å; I489-F508 HydrophobicContact CD1-CE2 3.36Å
490S94.9Very high91.4Very high57 Ų5752 Ų5240%0.39930%0.296SS..Hα-helixtrans-61.7-44.4175.8-168.60000111.8A486 S487 M488 L492 K493 Q494A486-S490 WeakPolarHBondContact O-CB 3.44Å; A486-S490 PolarHBondContact O-N 2.95Å; S487-S490 WeakPolarHBondContact O-CA 3.44Å; S487-S490 VanDerWaalsContact O-CB 3.3Å; S487-S490 WeakPolarHBondContact O-CB 3.34Å; S487-S490 PolarHBondContact O-N 3.15Å; M488-S490 VanDerWaalsContact C-N 3.31Å; M488-S490 PolarHBondContact O-N 3.42Å; S490-L492 PolarHBondContact O-N 2.86Å; S490-K493 WeakPolarHBondContact O-CB 3.44Å; S490-K493 PolarHBondContact O-N 2.56Å; S490-K493 VanDerWaalsContact O-N 3.15Å; S490-Q494 WeakPolarHBondContact O-CG 3.42Å; S490-Q494 PolarHBondContact O-N 3.09Å
491K94.9Very high91.6Very high32 Ų3250.3 Ų50.314%0.13928%0.283CS..Hα-helixtrans-61.9-43.6175.6-64.8178.2-162.8-61.80112.2E443 N447 M450 S487 M488 K493 Q494 A495E443-K491 WeakPolarHBondContact OE1-CE 3.29Å; E443-K491 IonicContact OE1-NZ 3.84Å; E443-K491 PolarHBondContact OE1-NZ 3.22Å; N447-K491 WeakPolarHBondContact OD1-CE 3.41Å; N447-K491 PolarHBondContact OD1-NZ 3.44Å; M450-K491 HydrophobicContact CE-CB 4.27Å; M450-K491 HydrophobicContact CG-CB 4.01Å; M450-K491 HydrophobicContact CG-CD 3.98Å; M450-K491 HydrophobicContact SD-CB 4.15Å; S487-K491 WeakPolarHBondContact O-CG 3.23Å; S487-K491 PolarHBondContact O-N 3.36Å; S487-K491 WeakPolarHBondContact OG-CE 3.37Å; M488-K491 PolarHBondContact O-N 3Å; K491-K493 VanDerWaalsContact C-N 3.29Å; K491-K493 PolarHBondContact O-N 3.05Å; K491-Q494 PolarHBondContact O-N 3.37Å; K491-A495 PolarHBondContact O-N 3.05Å
492L94.4Very high91.7Very high1 Ų151.2 Ų51.21%0.00529%0.289CS..Hα-helixtrans-62.8-36.1174.6-68.3172.6000112M450 F453 F462 Y466 M488 I489 S490 A495 C496 Y500 T501 L504M450-L492 HydrophobicContact CE-CD2 4.22Å; M450-L492 HydrophobicContact SD-CD2 4.08Å; F453-L492 HydrophobicContact CE1-CD2 4.09Å; F453-L492 HydrophobicContact CE2-CD2 4.1Å; F453-L492 HydrophobicContact CZ-CD2 3.86Å; F462-L492 HydrophobicContact CD1-CD2 4.39Å; F462-L492 HydrophobicContact CE1-CD1 4.06Å; F462-L492 HydrophobicContact CE1-CD2 3.7Å; F462-L492 HydrophobicContact CZ-CD2 4.42Å; Y466-L492 HydrophobicContact CD1-CD1 4.3Å; Y466-L492 HydrophobicContact CE1-CD1 4.16Å; M488-L492 HydrophobicContact CE-CD1 4.37Å; M488-L492 HydrophobicContact CE-CD2 4.18Å; M488-L492 HydrophobicContact CE-CG 4.19Å; M488-L492 WeakPolarHBondContact O-CG 3.23Å; M488-L492 PolarHBondContact O-N 3.06Å; I489-L492 PolarHBondContact O-N 3.43Å; S490-L492 PolarHBondContact O-N 2.86Å; L492-A495 PolarHBondContact O-N 3.09Å; L492-C496 PolarHBondContact O-N 3.47Å; L492-Y500 HydrophobicContact CB-CE1 4.47Å; L492-Y500 HydrophobicContact CD2-CE1 4.44Å; L492-T501 HydrophobicContact CB-CG2 3.71Å; L492-L504 HydrophobicContact CD1-CD1 4.19Å
493K93.1Very high91.8Very high85 Ų8552.2 Ų52.237%0.3729%0.289SS..Hα-helixtrans-66.9-40.1176.2-179178.5170.9-176.60111.4I489 S490 K491 G497 T501I489-K493 WeakPolarHBondContact O-CB 3.14Å; I489-K493 PolarHBondContact O-N 2.88Å; S490-K493 WeakPolarHBondContact O-CB 3.44Å; S490-K493 PolarHBondContact O-N 2.56Å; S490-K493 VanDerWaalsContact O-N 3.15Å; K491-K493 VanDerWaalsContact C-N 3.29Å; K491-K493 PolarHBondContact O-N 3.05Å; K493-G497 CarbonylContact O-C 3.4Å; K493-G497 WeakPolarHBondContact O-CA 3.36Å; K493-G497 PolarHBondContact O-N 2.95Å; K493-T501 HydrophobicContact CB-CG2 3.89Å; K493-T501 WeakPolarHBondContact CB-OG1 3.34Å
494Q91.6Very high91.9Very high161 Ų16146.4 Ų46.475%0.75226%0.258SS*.Hα-helixtrans-64.9-40.6175.8-70.4175.33.700111.6S490 K491S490-Q494 WeakPolarHBondContact O-CG 3.42Å; S490-Q494 PolarHBondContact O-N 3.09Å; K491-Q494 PolarHBondContact O-N 3.37Å
495A88.4Confident92Very high57 Ų5749 Ų4947%0.47127%0.268SS..Hα-helixtrans-77.4-37.1-177.500000114.3M450 F453 K491 L492M450-A495 HydrophobicContact CE-CB 3.85Å; F453-A495 HydrophobicContact CD1-CB 4.35Å; F453-A495 HydrophobicContact CE1-CB 4Å; K491-A495 PolarHBondContact O-N 3.05Å; L492-A495 PolarHBondContact O-N 3.09Å
496C87.8Confident92Very high29 Ų2954.1 Ų54.120%0.19629%0.287CS..Hα-helixtrans-121.9-3.8-170.9-64.80000114.9F453 L492 Y500F453-C496 VanDerWaalsContact CE1-SG 3.55Å; F453-C496 VanDerWaalsContact CZ-SG 3.58Å; L492-C496 PolarHBondContact O-N 3.47Å; C496-Y500 HydrophobicContact CB-CD1 3.62Å; C496-Y500 HydrophobicContact CB-CD2 3.83Å; C496-Y500 HydrophobicContact CB-CE1 4.15Å; C496-Y500 HydrophobicContact CB-CE2 4.33Å; C496-Y500 HydrophobicContact CB-CG 3.43Å; C496-Y500 VanDerWaalsContact CB-CG 3.43Å
497G88.6Confident92.1Very high32 Ų3251.7 Ų51.733%0.3327%0.267SS..  trans87.9177.8179.600000115.1K493 T501K493-G497 CarbonylContact O-C 3.4Å; K493-G497 WeakPolarHBondContact O-CA 3.36Å; K493-G497 PolarHBondContact O-N 2.95Å; G497-T501 PolarHBondContact O-OG1 2.95Å
498F88.5Confident91.8Very high124 Ų12452.6 Ų52.654%0.54427%0.268SS..Hα-helixtrans-68-44.7-173.6177.6-104.8000113.4Y500 T501 S502F498-Y500 PolarHBondContact O-N 2.8Å; F498-T501 PolarHBondContact O-N 2.68Å; F498-T501 PolarHBondContact O-OG1 3.07Å; F498-S502 PolarHBondContact O-N 3.23Å
499E86.9Confident91.7Very high140 Ų14057.6 Ų57.665%0.65429%0.291SS*.Hα-helixtrans-59.3-35.9-177.8-65.6-173.1165.100112.7T501 S502 R741E499-T501 VanDerWaalsContact C-N 3.31Å; E499-T501 PolarHBondContact O-N 3.13Å; E499-S502 PolarHBondContact O-OG 3.35Å; E499-R741 IonicContact OE2-NH2 3.42Å; E499-R741 PolarHBondContact OE2-NH2 2.78Å
500Y88.8Confident91.7Very high2 Ų257.7 Ų57.71%0.00829%0.292CS..Hα-helixtrans-63.8-34.9177.9-173-89.8000112.3K459 Q463 L492 C496 F498K459-Y500 HydrophobicContact CB-CE2 4.29Å; K459-Y500 PolarHBondContact O-OH 2.92Å; Q463-Y500 HydrophobicContact CB-CE1 4.19Å; Q463-Y500 HydrophobicContact CB-CE2 3.67Å; Q463-Y500 VanDerWaalsContact CB-CZ 3.47Å; Q463-Y500 VanDerWaalsContact CB-OH 3.31Å; Q463-Y500 WeakPolarHBondContact CB-OH 3.33Å; Q463-Y500 HydrophobicContact CG-CD1 4.27Å; Q463-Y500 HydrophobicContact CG-CD2 4.19Å; Q463-Y500 HydrophobicContact CG-CE1 3.84Å; Q463-Y500 HydrophobicContact CG-CE2 3.75Å; Q463-Y500 HydrophobicContact CG-CG 4.44Å; Q463-Y500 PolarHBondContact N-OH 2.95Å; Q463-Y500 PolarHBondContact NE2-O 3.47Å; L492-Y500 HydrophobicContact CB-CE1 4.47Å; L492-Y500 HydrophobicContact CD2-CE1 4.44Å; C496-Y500 HydrophobicContact CB-CD1 3.62Å; C496-Y500 HydrophobicContact CB-CD2 3.83Å; C496-Y500 HydrophobicContact CB-CE1 4.15Å; C496-Y500 HydrophobicContact CB-CE2 4.33Å; C496-Y500 HydrophobicContact CB-CG 3.43Å; C496-Y500 VanDerWaalsContact CB-CG 3.43Å; F498-Y500 PolarHBondContact O-N 2.8Å
501T93.1Very high91.6Very high0 Ų055.9 Ų55.90%028%0.277CS..Hα-helixtrans-101.3-10.6-176.651.90000114.2I489 L492 K493 G497 F498 E499 K503 L504 Q505I489-T501 HydrophobicContact CG2-CG2 4.33Å; L492-T501 HydrophobicContact CB-CG2 3.71Å; K493-T501 HydrophobicContact CB-CG2 3.89Å; K493-T501 WeakPolarHBondContact CB-OG1 3.34Å; G497-T501 PolarHBondContact O-OG1 2.95Å; F498-T501 PolarHBondContact O-N 2.68Å; F498-T501 PolarHBondContact O-OG1 3.07Å; E499-T501 VanDerWaalsContact C-N 3.31Å; E499-T501 PolarHBondContact O-N 3.13Å; T501-K503 PolarHBondContact O-N 3Å; T501-L504 HydrophobicContact CG2-CD1 4.46Å; T501-L504 WeakPolarHBondContact O-CA 3.35Å; T501-L504 WeakPolarHBondContact O-CB 3.35Å; T501-L504 PolarHBondContact O-N 3.42Å; T501-Q505 PolarHBondContact O-N 3.39Å
502S92Very high91.3Very high43 Ų4355.9 Ų55.930%0.30129%0.286SS..Hα-helixtrans-46.2-50.5-178620000114.3F498 E499 Q505 R506F498-S502 PolarHBondContact O-N 3.23Å; E499-S502 PolarHBondContact O-OG 3.35Å; S502-Q505 PolarHBondContact O-N 3.02Å; S502-R506 WeakPolarHBondContact O-CB 3.32Å; S502-R506 PolarHBondContact O-N 2.88Å
503K91.6Very high91.3Very high113 Ų11359.7 Ų59.749%0.49131%0.309SS..Hα-helixtrans-64.6-40.4178-66.6-173.8179.9-175.80112T501 R506 M507T501-K503 PolarHBondContact O-N 3Å; K503-R506 PolarHBondContact O-N 3.48Å; K503-M507 WeakPolarHBondContact O-CG 3.06Å; K503-M507 PolarHBondContact O-N 3.31Å
504L93.9Very high91.3Very high1 Ų155.7 Ų55.71%0.00529%0.292CS..Hα-helixtrans-63.2-45.7178.4-50.6-179.5000111.4Y466 A467 L470 I489 L492 T501 R506 M507 F508Y466-L504 HydrophobicContact CD1-CD1 4Å; Y466-L504 HydrophobicContact CD1-CD2 4.31Å; Y466-L504 HydrophobicContact CE1-CD1 4.15Å; A467-L504 HydrophobicContact CB-CD2 3.59Å; L470-L504 HydrophobicContact CD2-CB 4.15Å; L470-L504 HydrophobicContact CD2-CD2 4.1Å; I489-L504 HydrophobicContact CD1-CB 3.99Å; I489-L504 HydrophobicContact CG1-CB 4.2Å; I489-L504 HydrophobicContact CG1-CD1 4.41Å; I489-L504 HydrophobicContact CG2-CB 4.45Å; L492-L504 HydrophobicContact CD1-CD1 4.19Å; T501-L504 HydrophobicContact CG2-CD1 4.46Å; T501-L504 WeakPolarHBondContact O-CA 3.35Å; T501-L504 WeakPolarHBondContact O-CB 3.35Å; T501-L504 PolarHBondContact O-N 3.42Å; L504-R506 VanDerWaalsContact C-N 3.3Å; L504-R506 PolarHBondContact O-N 2.89Å; L504-M507 HydrophobicContact CB-CE 4.36Å; L504-M507 HydrophobicContact CD2-CE 3.45Å; L504-M507 VanDerWaalsContact CD2-CE 3.45Å; L504-M507 HydrophobicContact CG-CE 4.45Å; L504-M507 PolarHBondContact O-N 2.79Å; L504-F508 PolarHBondContact O-N 3.1Å
505Q92.8Very high91.3Very high65 Ų6553.2 Ų53.230%0.30428%0.279SS..Hα-helixtrans-62.7-39.6175.9-67.7-176.6-3300111.5I489 T501 S502 F508 Q509I489-Q505 HydrophobicContact CG2-CG 3.66Å; T501-Q505 PolarHBondContact O-N 3.39Å; S502-Q505 PolarHBondContact O-N 3.02Å; Q505-F508 WeakPolarHBondContact O-CB 3.37Å; Q505-F508 PolarHBondContact O-N 3.16Å; Q505-Q509 PolarHBondContact O-N 2.81Å
506R94.4Very high91.5Very high108 Ų10854.5 Ų54.541%0.40828%0.278SS..Hα-helixtrans-65.8-37.7176.8-170.363.3-167.7-158.1-6.3112.5S502 K503 L504 F508 Q509 D510 S544S502-R506 WeakPolarHBondContact O-CB 3.32Å; S502-R506 PolarHBondContact O-N 2.88Å; K503-R506 PolarHBondContact O-N 3.48Å; L504-R506 VanDerWaalsContact C-N 3.3Å; L504-R506 PolarHBondContact O-N 2.89Å; R506-F508 VanDerWaalsContact C-N 3.31Å; R506-F508 PolarHBondContact O-N 3.25Å; R506-Q509 PolarHBondContact O-N 3.4Å; R506-D510 IonicContact CZ-OD1 2.77Å; R506-D510 IonicContact NE-OD1 3.01Å; R506-D510 PolarHBondContact NE-OD1 3.08Å; R506-D510 IonicContact NH2-OD1 2.74Å; R506-D510 WeakPolarHBondContact O-CB 3.33Å; R506-D510 VanDerWaalsContact O-CG 3.25Å; R506-D510 PolarHBondContact O-N 2.85Å; R506-S544 VanDerWaalsContact CG-OG 3.32Å; R506-S544 WeakPolarHBondContact CG-OG 3.26Å
507M94.3Very high91.8Very high0 Ų053.6 Ų53.60%027%0.271CS..Hα-helixtrans-59.3-42.5173.8-69-171.5-74.800111.6A467 L470 A471 L474 K503 L504 D510 I511 W545A467-M507 HydrophobicContact CB-CE 4.17Å; L470-M507 HydrophobicContact CD2-CE 3.99Å; A471-M507 HydrophobicContact CB-SD 3.93Å; L474-M507 HydrophobicContact CD1-CB 3.87Å; K503-M507 WeakPolarHBondContact O-CG 3.06Å; K503-M507 PolarHBondContact O-N 3.31Å; L504-M507 HydrophobicContact CB-CE 4.36Å; L504-M507 HydrophobicContact CD2-CE 3.45Å; L504-M507 VanDerWaalsContact CD2-CE 3.45Å; L504-M507 HydrophobicContact CG-CE 4.45Å; L504-M507 PolarHBondContact O-N 2.79Å; M507-D510 PolarHBondContact O-N 3.33Å; M507-I511 WeakPolarHBondContact O-CG1 3.44Å; M507-I511 PolarHBondContact O-N 3.25Å; M507-W545 HydrophobicContact CB-CD2 4.37Å; M507-W545 HydrophobicContact CB-CH2 4.1Å; M507-W545 HydrophobicContact CB-CZ2 3.66Å; M507-W545 HydrophobicContact CG-CD2 3.69Å; M507-W545 HydrophobicContact CG-CE3 4.17Å; M507-W545 HydrophobicContact CG-CG 4.02Å; M507-W545 HydrophobicContact CG-CH2 4.4Å; M507-W545 HydrophobicContact CG-CZ2 3.93Å; M507-W545 WeakPolarHBondContact O-CZ2 3.36Å; M507-W545 HydrophobicContact SD-CD2 3.95Å; M507-W545 HydrophobicContact SD-CE3 3.91Å; M507-W545 HydrophobicContact SD-CG 4.34Å; M507-W545 HydrophobicContact SD-CZ3 4.32Å
508F89.6Confident92Very high49 Ų4952.9 Ų52.922%0.21526%0.26CS..Hα-helixtrans-61-46.4173.7-97.1-83.2000112.9L470 L474 E485 I489 L504 Q505 R506 D510 I511 G512L470-F508 HydrophobicContact CD1-CE2 3.71Å; L470-F508 HydrophobicContact CD1-CZ 4.18Å; L470-F508 HydrophobicContact CD2-CD2 4.41Å; L470-F508 HydrophobicContact CD2-CE2 4.04Å; L470-F508 HydrophobicContact CG-CE2 4.41Å; L474-F508 HydrophobicContact CD1-CD2 4.28Å; L474-F508 HydrophobicContact CD1-CE2 4.27Å; L474-F508 HydrophobicContact CD2-CD1 4.4Å; L474-F508 HydrophobicContact CD2-CE1 3.88Å; L474-F508 HydrophobicContact CD2-CE2 4.17Å; L474-F508 HydrophobicContact CD2-CZ 3.71Å; E485-F508 HydrophobicContact CB-CE1 4.18Å; E485-F508 HydrophobicContact CB-CE2 3.89Å; E485-F508 HydrophobicContact CB-CZ 3.26Å; E485-F508 HydrophobicContact CG-CZ 3.99Å; I489-F508 HydrophobicContact CD1-CD2 3.35Å; I489-F508 HydrophobicContact CD1-CE2 3.36Å; L504-F508 PolarHBondContact O-N 3.1Å; Q505-F508 WeakPolarHBondContact O-CB 3.37Å; Q505-F508 PolarHBondContact O-N 3.16Å; R506-F508 VanDerWaalsContact C-N 3.31Å; R506-F508 PolarHBondContact O-N 3.25Å; F508-D510 VanDerWaalsContact C-N 3.35Å; F508-D510 PolarHBondContact O-N 3.19Å; F508-I511 PolarHBondContact O-N 3.32Å; F508-G512 PolarHBondContact O-N 2.91Å
509Q92.1Very high92.2Very high104 Ų10452.2 Ų52.249%0.48626%0.258SS..Hα-helixtrans-61.7-43178.5-172.2179.224.300111.9Q505 R506 I511 G512 V513Q505-Q509 PolarHBondContact O-N 2.81Å; R506-Q509 PolarHBondContact O-N 3.4Å; Q509-I511 VanDerWaalsContact C-N 3.28Å; Q509-I511 PolarHBondContact O-N 2.81Å; Q509-G512 PolarHBondContact O-N 3.1Å; Q509-V513 HydrophobicContact CG-CG2 4.39Å; Q509-V513 WeakPolarHBondContact O-CG2 3.42Å; Q509-V513 PolarHBondContact O-N 3.35Å
510D94.3Very high92.5Very high9 Ų949.2 Ų49.25%0.04824%0.244CC..Hα-helixtrans-62.9-33.6-179.7-72.4-10.1000111.9R506 M507 F508 S514 S541 W545R506-D510 IonicContact CZ-OD1 2.77Å; R506-D510 IonicContact NE-OD1 3.01Å; R506-D510 PolarHBondContact NE-OD1 3.08Å; R506-D510 IonicContact NH2-OD1 2.74Å; R506-D510 WeakPolarHBondContact O-CB 3.33Å; R506-D510 VanDerWaalsContact O-CG 3.25Å; R506-D510 PolarHBondContact O-N 2.85Å; M507-D510 PolarHBondContact O-N 3.33Å; F508-D510 VanDerWaalsContact C-N 3.35Å; F508-D510 PolarHBondContact O-N 3.19Å; D510-S514 VanDerWaalsContact O-CB 3.26Å; D510-S514 WeakPolarHBondContact O-CB 3.5Å; D510-S514 PolarHBondContact O-N 2.85Å; D510-S514 PolarHBondContact O-OG 3.39Å; D510-S541 VanDerWaalsContact OD2-CB 3.23Å; D510-S541 WeakPolarHBondContact OD2-CB 3.44Å; D510-S541 PolarHBondContact OD2-N 3Å; D510-S541 PolarHBondContact OD2-OG 2.98Å; D510-W545 HydrophobicContact CB-CZ2 4.24Å; D510-W545 PolarHBondContact OD2-NE1 3.05Å
511I91.9Very high92.6Very high19 Ų1949.2 Ų49.210%0.09724%0.244CC..Hα-helixtrans-66.7-43.4173.9-67.4-64.1000111.4L474 M507 F508 Q509 S514 K515 L540 W545L474-I511 HydrophobicContact CB-CD1 4.23Å; L474-I511 HydrophobicContact CB-CG1 4.03Å; L474-I511 HydrophobicContact CD1-CG1 4.32Å; L474-I511 HydrophobicContact CD2-CG1 4.44Å; M507-I511 WeakPolarHBondContact O-CG1 3.44Å; M507-I511 PolarHBondContact O-N 3.25Å; F508-I511 PolarHBondContact O-N 3.32Å; Q509-I511 VanDerWaalsContact C-N 3.28Å; Q509-I511 PolarHBondContact O-N 2.81Å; I511-S514 PolarHBondContact O-N 3.41Å; I511-K515 WeakPolarHBondContact O-CG 3.12Å; I511-K515 PolarHBondContact O-N 3.24Å; I511-K515 VanDerWaalsContact O-N 3.09Å; I511-L540 HydrophobicContact CD1-CD2 4.21Å; I511-W545 HydrophobicContact CD1-CH2 3.84Å; I511-W545 HydrophobicContact CD1-CZ2 4.2Å; I511-W545 HydrophobicContact CG1-CH2 3.98Å; I511-W545 HydrophobicContact CG1-CZ2 4.13Å
512G90.3Very high92.5Very high32 Ų3254.3 Ų54.333%0.3327%0.266SS..Hα-helixtrans-60-51.4174.600000111.8F508 Q509 S514 K515 D516F508-G512 PolarHBondContact O-N 2.91Å; Q509-G512 PolarHBondContact O-N 3.1Å; G512-S514 PolarHBondContact O-N 3.36Å; G512-K515 WeakPolarHBondContact O-CB 3.33Å; G512-K515 PolarHBondContact O-N 2.65Å; G512-D516 PolarHBondContact O-N 3.07Å
513V93.3Very high92.3Very high80 Ų8058.8 Ų58.849%0.48528%0.281SS..Hα-helixtrans-60.3-35.5177.6174.40000111.8Q509 D516 L517Q509-V513 HydrophobicContact CG-CG2 4.39Å; Q509-V513 WeakPolarHBondContact O-CG2 3.42Å; Q509-V513 PolarHBondContact O-N 3.35Å; V513-D516 PolarHBondContact O-N 3.27Å; V513-L517 WeakPolarHBondContact O-CB 3.48Å; V513-L517 PolarHBondContact O-N 2.97Å
514S93.3Very high92.2Very high2 Ų257.1 Ų57.11%0.01427%0.274CS..Hα-helixtrans-65.6-37.1175.3-68.70000112.5D510 I511 G512 L517 N518 V539D510-S514 VanDerWaalsContact O-CB 3.26Å; D510-S514 WeakPolarHBondContact O-CB 3.5Å; D510-S514 PolarHBondContact O-N 2.85Å; D510-S514 PolarHBondContact O-OG 3.39Å; I511-S514 PolarHBondContact O-N 3.41Å; G512-S514 PolarHBondContact O-N 3.36Å; S514-L517 PolarHBondContact O-N 3.26Å; S514-N518 PolarHBondContact O-N 3.42Å; S514-N518 PolarHBondContact O-ND2 2.86Å; S514-V539 PolarHBondContact OG-N 3.38Å; S514-V539 PolarHBondContact OG-O 3.36Å; S514-V539 VanDerWaalsContact OG-O 3.07Å
515K91.6Very high91.8Very high108 Ų10858.4 Ų58.447%0.4728%0.281SS..Hα-helixtrans-62.2-48.8174.7-70.1176.1-178.5177.30110.4I511 G512 L517 N518 E519I511-K515 WeakPolarHBondContact O-CG 3.12Å; I511-K515 PolarHBondContact O-N 3.24Å; I511-K515 VanDerWaalsContact O-N 3.09Å; G512-K515 WeakPolarHBondContact O-CB 3.33Å; G512-K515 PolarHBondContact O-N 2.65Å; K515-L517 VanDerWaalsContact C-N 3.29Å; K515-L517 PolarHBondContact O-N 3.38Å; K515-N518 WeakPolarHBondContact O-CB 3.16Å; K515-N518 PolarHBondContact O-N 3.03Å; K515-N518 VanDerWaalsContact O-N 3.13Å; K515-E519 PolarHBondContact O-N 2.98Å; K515-E519 VanDerWaalsContact O-N 3.09Å
516D93.4Very high91.3Very high85 Ų8559.6 Ų59.646%0.45530%0.297SS..Hα-helixtrans-59.5-40.6177.4-62.7-18.7000112G512 V513 E519 Q520G512-D516 PolarHBondContact O-N 3.07Å; V513-D516 PolarHBondContact O-N 3.27Å; D516-E519 PolarHBondContact O-N 2.91Å; D516-Q520 VanDerWaalsContact O-CG 3.23Å; D516-Q520 WeakPolarHBondContact O-CG 3.49Å; D516-Q520 PolarHBondContact O-N 2.92Å
517L94Very high90.6Very high10 Ų1061.3 Ų61.35%0.05231%0.314CS..Hα-helixtrans-65.1-38.8177.9-173.865.3000112.2V513 S514 K515 Q520 F521 V539 F566 F569 Y570V513-L517 WeakPolarHBondContact O-CB 3.48Å; V513-L517 PolarHBondContact O-N 2.97Å; S514-L517 PolarHBondContact O-N 3.26Å; K515-L517 VanDerWaalsContact C-N 3.29Å; K515-L517 PolarHBondContact O-N 3.38Å; L517-Q520 PolarHBondContact O-N 2.73Å; L517-F521 WeakPolarHBondContact O-CB 3.12Å; L517-F521 PolarHBondContact O-N 3.08Å; L517-V539 HydrophobicContact CD2-CB 4.06Å; L517-V539 HydrophobicContact CD2-CG2 3.56Å; L517-F566 HydrophobicContact CD2-CE2 4.46Å; L517-F566 HydrophobicContact CD2-CZ 3.93Å; L517-F566 HydrophobicContact CG-CZ 4.46Å; L517-F569 HydrophobicContact CD1-CE1 3.8Å; L517-F569 HydrophobicContact CD1-CZ 4.41Å; L517-F569 HydrophobicContact CG-CE1 4.49Å; L517-Y570 HydrophobicContact CD2-CD2 3.97Å; L517-Y570 HydrophobicContact CD2-CE2 3.91Å
518N93Very high89.7Confident16 Ų1664 Ų649%0.08633%0.332CS..Hα-helixtrans-63.1-42.9174-78.7-68.6000111.7S514 K515 Q520 F521 K522 S536 I537S514-N518 PolarHBondContact O-N 3.42Å; S514-N518 PolarHBondContact O-ND2 2.86Å; K515-N518 WeakPolarHBondContact O-CB 3.16Å; K515-N518 PolarHBondContact O-N 3.03Å; K515-N518 VanDerWaalsContact O-N 3.13Å; N518-Q520 VanDerWaalsContact C-N 3.33Å; N518-Q520 PolarHBondContact O-N 3.47Å; N518-F521 PolarHBondContact O-N 2.89Å; N518-K522 WeakPolarHBondContact O-CG 3.41Å; N518-K522 PolarHBondContact O-N 3.3Å; N518-S536 WeakPolarHBondContact OD1-CA 3.29Å; N518-S536 PolarHBondContact OD1-OG 2.94Å; N518-I537 PolarHBondContact ND2-O 2.94Å; N518-I537 PolarHBondContact OD1-N 3.22Å; N518-I537 PolarHBondContact OD1-O 3.45Å
519E92.6Very high89.1Confident111 Ų11167.5 Ų67.552%0.51935%0.35SS..Hα-helixtrans-62.9-41.9176.8-68.2-176.3-176.600111.8K515 D516 F521 K522 K523K515-E519 PolarHBondContact O-N 2.98Å; K515-E519 VanDerWaalsContact O-N 3.09Å; D516-E519 PolarHBondContact O-N 2.91Å; E519-F521 VanDerWaalsContact C-N 3.32Å; E519-F521 PolarHBondContact O-N 3.48Å; E519-K522 PolarHBondContact O-N 3.19Å; E519-K523 WeakPolarHBondContact O-CG 3.4Å; E519-K523 PolarHBondContact O-N 3.1Å
520Q92Very high88.3Confident77 Ų7767.3 Ų67.336%0.3636%0.358SS..Hα-helixtrans-63.1-38.9175.1-70.8170.334.300112.1D516 L517 N518 H524 F569D516-Q520 VanDerWaalsContact O-CG 3.23Å; D516-Q520 WeakPolarHBondContact O-CG 3.49Å; D516-Q520 PolarHBondContact O-N 2.92Å; L517-Q520 PolarHBondContact O-N 2.73Å; N518-Q520 VanDerWaalsContact C-N 3.33Å; N518-Q520 PolarHBondContact O-N 3.47Å; Q520-H524 PolarHBondContact O-N 3Å; Q520-F569 HydrophobicContact CB-CZ 4.14Å
521F91.9Very high87.8Confident2 Ų268.1 Ų68.11%0.00936%0.362CS..Hα-helixtrans-68-43.1176.1-176.4-120.1000111.7L517 N518 E519 K523 H524 L525 L531 F535 R565 F566 F569L517-F521 WeakPolarHBondContact O-CB 3.12Å; L517-F521 PolarHBondContact O-N 3.08Å; N518-F521 PolarHBondContact O-N 2.89Å; E519-F521 VanDerWaalsContact C-N 3.32Å; E519-F521 PolarHBondContact O-N 3.48Å; F521-K523 VanDerWaalsContact C-N 3.32Å; F521-K523 PolarHBondContact O-N 3.02Å; F521-H524 WeakPolarHBondContact O-CB 3.46Å; F521-H524 PolarHBondContact O-N 3.47Å; F521-L525 HydrophobicContact CD1-CD1 3.83Å; F521-L525 HydrophobicContact CD1-CG 4.42Å; F521-L525 HydrophobicContact CE1-CD1 3.44Å; F521-L525 VanDerWaalsContact CE1-CD1 3.44Å; F521-L525 HydrophobicContact CE1-CG 4.08Å; F521-L525 HydrophobicContact CE2-CD1 4.43Å; F521-L525 HydrophobicContact CE2-CD2 4.32Å; F521-L525 HydrophobicContact CE2-CG 4.18Å; F521-L525 HydrophobicContact CG-CD1 4.48Å; F521-L525 HydrophobicContact CZ-CD1 3.78Å; F521-L525 HydrophobicContact CZ-CD2 4.01Å; F521-L525 HydrophobicContact CZ-CG 3.95Å; F521-L525 WeakPolarHBondContact O-CG 3.49Å; F521-L525 PolarHBondContact O-N 3.45Å; F521-L531 HydrophobicContact CE1-CD1 4.12Å; F521-L531 HydrophobicContact CZ-CD1 4.39Å; F521-F535 HydrophobicContact CD1-CD1 4.13Å; F521-F535 HydrophobicContact CD1-CE1 4.49Å; F521-F535 AromaticContact CE1-CD1 3.61Å; F521-F535 HydrophobicContact CE1-CD1 3.61Å; F521-F535 HydrophobicContact CE1-CE1 4.01Å; F521-R565 HydrophobicContact CZ-CB 4.38Å; F521-F566 AromaticContact CD1-CD2 3.97Å; F521-F566 HydrophobicContact CD1-CD2 3.97Å; F521-F566 AromaticContact CD2-CD2 3.96Å; F521-F566 HydrophobicContact CD2-CD2 3.96Å; F521-F566 HydrophobicContact CE1-CB 4.4Å; F521-F566 HydrophobicContact CE1-CD2 4.09Å; F521-F566 HydrophobicContact CE2-CB 4.29Å; F521-F566 HydrophobicContact CE2-CD2 4.09Å; F521-F566 AromaticContact CG-CD2 3.89Å; F521-F566 HydrophobicContact CG-CD2 3.89Å; F521-F566 HydrophobicContact CG-CE2 4.34Å; F521-F566 HydrophobicContact CZ-CB 3.98Å; F521-F566 HydrophobicContact CZ-CD2 4.15Å; F521-F569 HydrophobicContact CB-CD1 4.26Å; F521-F569 HydrophobicContact CB-CE1 3.83Å; F521-F569 HydrophobicContact CB-CZ 4.07Å; F521-F569 HydrophobicContact CD2-CB 3.93Å; F521-F569 AromaticContact CD2-CD1 3.54Å; F521-F569 HydrophobicContact CD2-CD1 3.54Å; F521-F569 HydrophobicContact CD2-CD2 4.01Å; F521-F569 AromaticContact CD2-CE1 3.98Å; F521-F569 HydrophobicContact CD2-CE1 3.98Å; F521-F569 HydrophobicContact CD2-CE2 4.38Å; F521-F569 AromaticContact CD2-CG 3.55Å; F521-F569 HydrophobicContact CD2-CG 3.55Å; F521-F569 HydrophobicContact CD2-CZ 4.37Å; F521-F569 HydrophobicContact CE2-CB 3.91Å; F521-F569 HydrophobicContact CE2-CD1 4.3Å; F521-F569 HydrophobicContact CE2-CG 4.07Å; F521-F569 HydrophobicContact CG-CD1 4.26Å; F521-F569 HydrophobicContact CG-CE1 4.34Å
522K89.9Confident87.3Confident106 Ų10673.5 Ų73.546%0.46139%0.391SS..Hα-helixtrans-59-41.2174.6-73-177.3178.9-164.50112N518 E519 H524 L525 S526 D534N518-K522 WeakPolarHBondContact O-CG 3.41Å; N518-K522 PolarHBondContact O-N 3.3Å; E519-K522 PolarHBondContact O-N 3.19Å; K522-H524 VanDerWaalsContact C-N 3.35Å; K522-L525 PolarHBondContact O-N 3.45Å; K522-S526 PolarHBondContact O-N 2.79Å; K522-S526 VanDerWaalsContact O-N 3.09Å; K522-D534 IonicContact NZ-OD1 3.68Å
523K89.1Confident87.2Confident138 Ų13874.7 Ų74.760%0.639%0.389SS*.Hα-helixtrans-66.8-31.9173.1-71.5173.4-177.9171.60113.4E519 F521 S526E519-K523 WeakPolarHBondContact O-CG 3.4Å; E519-K523 PolarHBondContact O-N 3.1Å; F521-K523 VanDerWaalsContact C-N 3.32Å; F521-K523 PolarHBondContact O-N 3.02Å; K523-S526 PolarHBondContact O-OG 2.81Å
524H88.1Confident86.9Confident78 Ų7877.8 Ų77.836%0.36140%0.403SS..Hα-helixtrans-71.2-39.6174.2-179.1-84.9000111.2Q520 F521 K522 S526 N527 F569Q520-H524 PolarHBondContact O-N 3Å; F521-H524 WeakPolarHBondContact O-CB 3.46Å; F521-H524 PolarHBondContact O-N 3.47Å; K522-H524 VanDerWaalsContact C-N 3.35Å; H524-S526 VanDerWaalsContact C-N 3.35Å; H524-S526 PolarHBondContact O-N 3.37Å; H524-N527 PolarHBondContact O-N 3.41Å; H524-F569 HydrophobicContact CB-CD2 3.91Å; H524-F569 HydrophobicContact CB-CE2 3.7Å; H524-F569 AromaticContact CD2-CD2 3.87Å; H524-F569 AromaticContact CG-CD2 3.66Å; H524-F569 AromaticContact CG-CE2 3.92Å
525L86.5Confident86.8Confident27 Ų2779.3 Ų79.314%0.14141%0.409CS..Hα-helixtrans-66.2-31.9177-74173.5000113.1F521 K522 N527 S528 L531F521-L525 HydrophobicContact CD1-CD1 3.83Å; F521-L525 HydrophobicContact CD1-CG 4.42Å; F521-L525 HydrophobicContact CE1-CD1 3.44Å; F521-L525 VanDerWaalsContact CE1-CD1 3.44Å; F521-L525 HydrophobicContact CE1-CG 4.08Å; F521-L525 HydrophobicContact CE2-CD1 4.43Å; F521-L525 HydrophobicContact CE2-CD2 4.32Å; F521-L525 HydrophobicContact CE2-CG 4.18Å; F521-L525 HydrophobicContact CG-CD1 4.48Å; F521-L525 HydrophobicContact CZ-CD1 3.78Å; F521-L525 HydrophobicContact CZ-CD2 4.01Å; F521-L525 HydrophobicContact CZ-CG 3.95Å; F521-L525 WeakPolarHBondContact O-CG 3.49Å; F521-L525 PolarHBondContact O-N 3.45Å; K522-L525 PolarHBondContact O-N 3.45Å; L525-N527 PolarHBondContact O-N 2.89Å; L525-N527 VanDerWaalsContact O-N 3.17Å; L525-S528 CarbonylContact O-C 3.56Å; L525-S528 PolarHBondContact O-N 2.85Å; L525-L531 HydrophobicContact CD1-CD1 3.66Å; L525-L531 HydrophobicContact CD1-CG 4.02Å; L525-L531 HydrophobicContact CD2-CD1 4.37Å; L525-L531 HydrophobicContact CD2-CG 4.07Å
526S82Confident86.8Confident91 Ų9178 Ų7864%0.63641%0.413SS*.THydrogen-bonded Turntrans-63.2-20.2175.262.10000113.6K522 K523 H524K522-S526 PolarHBondContact O-N 2.79Å; K522-S526 VanDerWaalsContact O-N 3.09Å; K523-S526 PolarHBondContact O-OG 2.81Å; H524-S526 VanDerWaalsContact C-N 3.35Å; H524-S526 PolarHBondContact O-N 3.37Å
527N78.8Confident86.7Confident143 Ų14375 Ų7577%0.76540%0.398SS*.THydrogen-bonded Turntrans-95.97.7176.7-60.9-12.1000112.3H524 L525H524-N527 PolarHBondContact O-N 3.41Å; L525-N527 PolarHBondContact O-N 2.89Å; L525-N527 VanDerWaalsContact O-N 3.17Å
528S76.8Confident86.7Confident56 Ų5677.1 Ų77.139%0.39241%0.407SS..SBendtrans-137.9179.9-177.1-67.20000110L525L525-S528 CarbonylContact O-C 3.56Å; L525-S528 PolarHBondContact O-N 2.85Å
529E75.4Confident86.7Confident124 Ų12477.7 Ų77.758%0.57941%0.411SS*.PPolyproline II helixtrans-61.1135.6170.5-72.9-177.3157.900111R561E529-R561 IonicContact OE2-NH2 2.83Å; E529-R561 PolarHBondContact OE2-NH2 3.09Å
530P77.3Confident86.7Confident100 Ų10074.7 Ų74.765%0.64940%0.398SS*.PPolyproline II helixtrans-65.2151.8177.727.9-33.6000111
531L82.7Confident86.7Confident26 Ų2672.6 Ų72.614%0.13639%0.392CS..PPolyproline II helixtrans-73.4149.9169.3-66.8173.9000109.8F521 L525 L533 F535 R561 R565F521-L531 HydrophobicContact CE1-CD1 4.12Å; F521-L531 HydrophobicContact CZ-CD1 4.39Å; L525-L531 HydrophobicContact CD1-CD1 3.66Å; L525-L531 HydrophobicContact CD1-CG 4.02Å; L525-L531 HydrophobicContact CD2-CD1 4.37Å; L525-L531 HydrophobicContact CD2-CG 4.07Å; L531-L533 PolarHBondContact O-N 3.27Å; L531-F535 HydrophobicContact CD1-CB 3.75Å; L531-F535 HydrophobicContact CD1-CG 4.29Å; L531-R561 HydrophobicContact CD2-CG 4.4Å; L531-R565 HydrophobicContact CD2-CB 4.49Å; L531-R565 HydrophobicContact CD2-CG 4.33Å
532D81.4Confident86.5Confident132 Ų13278 Ų7871%0.70643%0.431SS*.SBendtrans-73.5-2.2177.4-53.1-56.8000112.7R561D532-R561 IonicContact OD1-NH1 2.7Å; D532-R561 IonicContact OD2-CZ 2.81Å; D532-R561 IonicContact OD2-NH1 3.53Å; D532-R561 PolarHBondContact OD2-NH1 3.46Å
533L87.4Confident86.2Confident56 Ų5676 Ų7629%0.29344%0.439SS..SBendtrans-144.4155.2-177.864.792.1000112.3L531 F535 E558 L559L531-L533 PolarHBondContact O-N 3.27Å; L533-F535 HydrophobicContact CD1-CB 3.72Å; L533-F535 HydrophobicContact CD1-CD2 4.14Å; L533-F535 HydrophobicContact CD1-CG 4.42Å; L533-F535 PolarHBondContact O-N 3.24Å; L533-E558 WeakPolarHBondContact CD2-O 3.48Å; L533-L559 HydrophobicContact CD2-CD2 3.78Å
534D88.3Confident86.2Confident145 Ų14570.6 Ų70.678%0.77542%0.419SS*.  trans-75.3111.2170.3-174.620000109.8K522K522-D534 IonicContact NZ-OD1 3.68Å
535F90.6Very high86.3Confident35 Ų3567.7 Ų67.715%0.15441%0.405CS..  trans-110.8130.7-172.5-177.1-101.1000111.4F521 L531 L533 I537 F566 W581F521-F535 HydrophobicContact CD1-CD1 4.13Å; F521-F535 HydrophobicContact CD1-CE1 4.49Å; F521-F535 AromaticContact CE1-CD1 3.61Å; F521-F535 HydrophobicContact CE1-CD1 3.61Å; F521-F535 HydrophobicContact CE1-CE1 4.01Å; L531-F535 HydrophobicContact CD1-CB 3.75Å; L531-F535 HydrophobicContact CD1-CG 4.29Å; L533-F535 HydrophobicContact CD1-CB 3.72Å; L533-F535 HydrophobicContact CD1-CD2 4.14Å; L533-F535 HydrophobicContact CD1-CG 4.42Å; L533-F535 PolarHBondContact O-N 3.24Å; F535-I537 HydrophobicContact CE1-CB 3.91Å; F535-I537 HydrophobicContact CE1-CG2 3.87Å; F535-I537 HydrophobicContact CZ-CB 3.94Å; F535-I537 HydrophobicContact CZ-CD1 4.01Å; F535-I537 HydrophobicContact CZ-CG2 4.36Å; F535-F566 HydrophobicContact CE1-CB 3.85Å; F535-F566 AromaticContact CE1-CD2 4Å; F535-F566 HydrophobicContact CE1-CD2 4Å; F535-F566 AromaticContact CE1-CG 3.95Å; F535-F566 HydrophobicContact CE1-CG 3.95Å; F535-F566 HydrophobicContact CZ-CB 4.17Å; F535-F566 HydrophobicContact CZ-CG 4.38Å; F535-W581 HydrophobicContact CZ-CH2 4.21Å; F535-W581 HydrophobicContact CZ-CZ3 4.35Å
536S91.3Very high86.3Confident79 Ų7968.1 Ų68.155%0.55241%0.409SS*.  trans-139.4144.3169.9-177.40000110.1N518N518-S536 WeakPolarHBondContact OD1-CA 3.29Å; N518-S536 PolarHBondContact OD1-OG 2.94Å
537I92.4Very high86.3Confident24 Ų2465.5 Ų65.512%0.12339%0.387CS..  trans-137.5147.1-175.8-174.8152.3000112.2N518 F535 V539 F566 W581N518-I537 PolarHBondContact ND2-O 2.94Å; N518-I537 PolarHBondContact OD1-N 3.22Å; N518-I537 PolarHBondContact OD1-O 3.45Å; F535-I537 HydrophobicContact CE1-CB 3.91Å; F535-I537 HydrophobicContact CE1-CG2 3.87Å; F535-I537 HydrophobicContact CZ-CB 3.94Å; F535-I537 HydrophobicContact CZ-CD1 4.01Å; F535-I537 HydrophobicContact CZ-CG2 4.36Å; I537-V539 HydrophobicContact CG1-CG2 4.47Å; I537-F566 HydrophobicContact CD1-CD1 3.67Å; I537-F566 HydrophobicContact CD1-CE1 3.61Å; I537-F566 HydrophobicContact CD1-CG 4.34Å; I537-F566 HydrophobicContact CD1-CZ 4.26Å; I537-F566 HydrophobicContact CG1-CE1 4.24Å; I537-F566 HydrophobicContact CG1-CZ 4.45Å; I537-F566 HydrophobicContact CG2-CD1 4.31Å; I537-F566 HydrophobicContact CG2-CD2 3.77Å; I537-F566 HydrophobicContact CG2-CE1 3.9Å; I537-F566 HydrophobicContact CG2-CE2 3.31Å; I537-F566 HydrophobicContact CG2-CG 4.24Å; I537-F566 HydrophobicContact CG2-CZ 3.37Å; I537-W581 HydrophobicContact CD1-CE3 4.08Å; I537-W581 HydrophobicContact CD1-CH2 3.25Å; I537-W581 HydrophobicContact CD1-CZ2 4.05Å; I537-W581 HydrophobicContact CD1-CZ3 3.26Å
538Q93.3Very high86.1Confident54 Ų5464.5 Ų64.525%0.25238%0.377SS..  trans-112.6118.7173.5-67.5177.2-17.300109.2V475 L540V475-Q538 PolarHBondContact O-NE2 3.05Å; Q538-L540 HydrophobicContact CB-CD2 4.05Å; Q538-L540 HydrophobicContact CB-CG 4.43Å
539V93.3Very high85.8Confident28 Ų2869.4 Ų69.417%0.1739%0.394CS..  trans-100.7110.9179.1-179.60000108.7S514 L517 I537 F566 Y570 L579S514-V539 PolarHBondContact OG-N 3.38Å; S514-V539 PolarHBondContact OG-O 3.36Å; S514-V539 VanDerWaalsContact OG-O 3.07Å; L517-V539 HydrophobicContact CD2-CB 4.06Å; L517-V539 HydrophobicContact CD2-CG2 3.56Å; I537-V539 HydrophobicContact CG1-CG2 4.47Å; V539-F566 HydrophobicContact CG2-CE1 4.04Å; V539-F566 HydrophobicContact CG2-CZ 3.8Å; V539-Y570 HydrophobicContact CG1-CE2 3.83Å; V539-Y570 HydrophobicContact CG2-CD2 4.49Å; V539-Y570 HydrophobicContact CG2-CE2 4.22Å; V539-L579 HydrophobicContact CG1-CD2 4.16Å
540L93.2Very high85.2Confident47 Ų4764.9 Ų64.925%0.24638%0.376CS..  trans-112.8143.5-168.9-50.7-177.3000110.8V475 I511 Q538 S542 W545 F547V475-L540 HydrophobicContact CG2-CD1 3.98Å; I511-L540 HydrophobicContact CD1-CD2 4.21Å; Q538-L540 HydrophobicContact CB-CD2 4.05Å; Q538-L540 HydrophobicContact CB-CG 4.43Å; L540-S542 PolarHBondContact O-N 3.36Å; L540-W545 HydrophobicContact CB-CD2 4.03Å; L540-W545 HydrophobicContact CB-CG 4.01Å; L540-W545 HydrophobicContact CD1-CD2 3.8Å; L540-W545 HydrophobicContact CD1-CE3 3.77Å; L540-W545 HydrophobicContact CD1-CG 4.42Å; L540-W545 HydrophobicContact CD1-CH2 4.13Å; L540-W545 HydrophobicContact CD1-CZ2 4.18Å; L540-W545 HydrophobicContact CD1-CZ3 3.93Å; L540-W545 HydrophobicContact CD2-CD2 4.4Å; L540-W545 HydrophobicContact CD2-CH2 3.94Å; L540-W545 HydrophobicContact CD2-CZ2 3.48Å; L540-W545 VanDerWaalsContact CD2-CZ2 3.48Å; L540-W545 HydrophobicContact CG-CD2 4.29Å; L540-W545 HydrophobicContact CG-CZ2 4.24Å; L540-F547 HydrophobicContact CD1-CD2 4.2Å; L540-F547 HydrophobicContact CD1-CE2 3.87Å
541S91.9Very high84.7Confident33 Ų3362.6 Ų62.623%0.23136%0.362CS..  trans-76.2116.6178.161.70000112.2D510 G543 S544 W545D510-S541 VanDerWaalsContact OD2-CB 3.23Å; D510-S541 WeakPolarHBondContact OD2-CB 3.44Å; D510-S541 PolarHBondContact OD2-N 3Å; D510-S541 PolarHBondContact OD2-OG 2.98Å; S541-G543 PolarHBondContact O-N 3.3Å; S541-S544 PolarHBondContact O-N 3.24Å; S541-S544 WeakPolarHBondContact OG-CB 3.31Å; S541-S544 PolarHBondContact OG-OG 3.36Å; S541-W545 VanDerWaalsContact O-CD1 3.22Å; S541-W545 PolarHBondContact O-N 3.24Å
542S86.4Confident84.3Confident117 Ų11766.2 Ų66.282%0.81839%0.385SS*.THydrogen-bonded Turntrans-52-34.5-175.4-177.20000114.5L540L540-S542 PolarHBondContact O-N 3.36Å
543G85.1Confident84.6Confident62 Ų6261.2 Ų61.264%0.63936%0.357SS*.THydrogen-bonded Turntrans-78-16.4-178.800000116.3S541S541-G543 PolarHBondContact O-N 3.3Å
544S88Confident84.7Confident25 Ų2560.4 Ų60.418%0.17536%0.359CS..THydrogen-bonded Turntrans-103.9-23-174.4-46.50000113R506 S541R506-S544 VanDerWaalsContact CG-OG 3.32Å; R506-S544 WeakPolarHBondContact CG-OG 3.26Å; S541-S544 PolarHBondContact O-N 3.24Å; S541-S544 WeakPolarHBondContact OG-CB 3.31Å; S541-S544 PolarHBondContact OG-OG 3.36Å
545W91Very high84.7Confident17 Ų1755.1 Ų55.16%0.06433%0.33CS..SBendtrans-98.8142.3-174.6-69.775.1000111.1A471 L474 V475 M507 D510 I511 L540 S541 F547A471-W545 HydrophobicContact CB-CE3 3.7Å; A471-W545 HydrophobicContact CB-CZ3 3.83Å; L474-W545 HydrophobicContact CB-CH2 3.96Å; L474-W545 HydrophobicContact CB-CZ3 4.36Å; L474-W545 HydrophobicContact CD1-CH2 4.04Å; V475-W545 HydrophobicContact CG2-CH2 4.33Å; V475-W545 HydrophobicContact CG2-CZ3 3.76Å; M507-W545 HydrophobicContact CB-CD2 4.37Å; M507-W545 HydrophobicContact CB-CH2 4.1Å; M507-W545 HydrophobicContact CB-CZ2 3.66Å; M507-W545 HydrophobicContact CG-CD2 3.69Å; M507-W545 HydrophobicContact CG-CE3 4.17Å; M507-W545 HydrophobicContact CG-CG 4.02Å; M507-W545 HydrophobicContact CG-CH2 4.4Å; M507-W545 HydrophobicContact CG-CZ2 3.93Å; M507-W545 WeakPolarHBondContact O-CZ2 3.36Å; M507-W545 HydrophobicContact SD-CD2 3.95Å; M507-W545 HydrophobicContact SD-CE3 3.91Å; M507-W545 HydrophobicContact SD-CG 4.34Å; M507-W545 HydrophobicContact SD-CZ3 4.32Å; D510-W545 HydrophobicContact CB-CZ2 4.24Å; D510-W545 PolarHBondContact OD2-NE1 3.05Å; I511-W545 HydrophobicContact CD1-CH2 3.84Å; I511-W545 HydrophobicContact CD1-CZ2 4.2Å; I511-W545 HydrophobicContact CG1-CH2 3.98Å; I511-W545 HydrophobicContact CG1-CZ2 4.13Å; L540-W545 HydrophobicContact CB-CD2 4.03Å; L540-W545 HydrophobicContact CB-CG 4.01Å; L540-W545 HydrophobicContact CD1-CD2 3.8Å; L540-W545 HydrophobicContact CD1-CE3 3.77Å; L540-W545 HydrophobicContact CD1-CG 4.42Å; L540-W545 HydrophobicContact CD1-CH2 4.13Å; L540-W545 HydrophobicContact CD1-CZ2 4.18Å; L540-W545 HydrophobicContact CD1-CZ3 3.93Å; L540-W545 HydrophobicContact CD2-CD2 4.4Å; L540-W545 HydrophobicContact CD2-CH2 3.94Å; L540-W545 HydrophobicContact CD2-CZ2 3.48Å; L540-W545 VanDerWaalsContact CD2-CZ2 3.48Å; L540-W545 HydrophobicContact CG-CD2 4.29Å; L540-W545 HydrophobicContact CG-CZ2 4.24Å; S541-W545 VanDerWaalsContact O-CD1 3.22Å; S541-W545 PolarHBondContact O-N 3.24Å; W545-F547 HydrophobicContact CB-CD2 4.12Å; W545-F547 HydrophobicContact CD2-CE2 4.27Å; W545-F547 AromaticContact CE3-CD2 3.99Å; W545-F547 HydrophobicContact CE3-CD2 3.99Å; W545-F547 AromaticContact CE3-CE2 3.32Å; W545-F547 HydrophobicContact CE3-CE2 3.32Å; W545-F547 AromaticContact CE3-CZ 3.98Å; W545-F547 HydrophobicContact CE3-CZ 3.98Å; W545-F547 AromaticContact CZ3-CE2 3.83Å; W545-F547 HydrophobicContact CZ3-CE2 3.83Å; W545-F547 HydrophobicContact CZ3-CZ 4.25Å; W545-F547 PolarHBondContact O-N 3.46Å
546P85.1Confident84.7Confident37 Ų3753.9 Ų53.924%0.2433%0.326CS..  trans-83.613-175.233-33000113.8K468 A471K468-P546 HydrophobicContact CB-CG 4.31Å; A471-P546 HydrophobicContact CB-CG 3.68Å
547F83.3Confident84.7Confident36 Ų3654.6 Ų54.616%0.15833%0.331CS..PPolyproline II helixtrans-82.6136-176.9-55.9-46.7000111.3A471 V475 L540 W545 L582 L585A471-F547 HydrophobicContact CB-CE1 4.04Å; A471-F547 HydrophobicContact CB-CE2 4.3Å; A471-F547 HydrophobicContact CB-CZ 3.66Å; V475-F547 HydrophobicContact CG2-CE2 3.67Å; V475-F547 HydrophobicContact CG2-CZ 3.76Å; L540-F547 HydrophobicContact CD1-CD2 4.2Å; L540-F547 HydrophobicContact CD1-CE2 3.87Å; W545-F547 HydrophobicContact CB-CD2 4.12Å; W545-F547 HydrophobicContact CD2-CE2 4.27Å; W545-F547 AromaticContact CE3-CD2 3.99Å; W545-F547 HydrophobicContact CE3-CD2 3.99Å; W545-F547 AromaticContact CE3-CE2 3.32Å; W545-F547 HydrophobicContact CE3-CE2 3.32Å; W545-F547 AromaticContact CE3-CZ 3.98Å; W545-F547 HydrophobicContact CE3-CZ 3.98Å; W545-F547 AromaticContact CZ3-CE2 3.83Å; W545-F547 HydrophobicContact CZ3-CE2 3.83Å; W545-F547 HydrophobicContact CZ3-CZ 4.25Å; W545-F547 PolarHBondContact O-N 3.46Å; F547-L582 HydrophobicContact CB-CD1 3.67Å; F547-L582 HydrophobicContact CD2-CD1 4.18Å; F547-L582 HydrophobicContact CG-CD1 4.25Å; F547-L585 HydrophobicContact CB-CD1 4.16Å; F547-L585 HydrophobicContact CD1-CD1 3.59Å; F547-L585 HydrophobicContact CD1-CD2 4.44Å; F547-L585 HydrophobicContact CD2-CD1 3.57Å; F547-L585 HydrophobicContact CE1-CD1 3.75Å; F547-L585 HydrophobicContact CE1-CD2 4.21Å; F547-L585 HydrophobicContact CE2-CD1 3.71Å; F547-L585 HydrophobicContact CG-CD1 3.5Å; F547-L585 VanDerWaalsContact CG-CD1 3.5Å; F547-L585 HydrophobicContact CZ-CD1 3.8Å
548Q74.3Confident84.5Confident121 Ų12157.5 Ų57.557%0.56534%0.344SS*.PPolyproline II helixtrans-95.8152.4174.8-67.5-179.4-25.300109.8S550Q548-S550 PolarHBondContact O-N 3.28Å
549Q69.3Low84.4Confident159 Ų15956.5 Ų56.574%0.74334%0.34SS*.PPolyproline II helixtrans-62.1129.9175.7-174.9173.1-0.400109.7T580Q549-T580 HydrophobicContact CG-CG2 3.86Å
550S63.9Low84.3Confident30 Ų3058.2 Ų58.221%0.2135%0.346CS..PPolyproline II helixtrans-80.4167.3-179.946.10000113.5Q548 H584Q548-S550 PolarHBondContact O-N 3.28Å; S550-H584 VanDerWaalsContact CB-ND1 3.3Å; S550-H584 WeakPolarHBondContact CB-ND1 3.39Å; S550-H584 PolarHBondContact OG-ND1 3.13Å
551C66.1Low84.1Confident52 Ų5259.8 Ų59.835%0.35135%0.349SS..PPolyproline II helixtrans-54.8169.7175.457.40000114.4
552T74.4Confident84.1Confident102 Ų10258.4 Ų58.463%0.62634%0.339SS*.PPolyproline II helixtrans-52.7139.4164.548.50000110Q630T552-Q630 CarbonylContact C-O 3.53Å; T552-Q630 PolarHBondContact OG1-O 2.88Å
553F88.3Confident84.3Confident27 Ų2756 Ų5612%0.11831%0.312CS..  trans-157.6128.6179.3173.8-110.5000108.4L555 Y583 T605 F606 A609 I631F553-L555 HydrophobicContact CE1-CB 4.47Å; F553-L555 HydrophobicContact CE1-CD1 3.95Å; F553-Y583 HydrophobicContact CB-CD2 4.21Å; F553-Y583 HydrophobicContact CD1-CD1 4.24Å; F553-Y583 AromaticContact CD1-CD2 3.45Å; F553-Y583 HydrophobicContact CD1-CD2 3.45Å; F553-Y583 VanDerWaalsContact CD1-CD2 3.45Å; F553-Y583 AromaticContact CD1-CE2 3.97Å; F553-Y583 HydrophobicContact CD1-CE2 3.97Å; F553-Y583 AromaticContact CD1-CG 3.59Å; F553-Y583 HydrophobicContact CD1-CG 3.59Å; F553-Y583 HydrophobicContact CE1-CD1 4.23Å; F553-Y583 HydrophobicContact CE1-CD2 4.23Å; F553-Y583 AromaticContact CE1-CG 3.93Å; F553-Y583 HydrophobicContact CE1-CG 3.93Å; F553-Y583 HydrophobicContact CG-CD2 4.21Å; F553-T605 HydrophobicContact CE1-CG2 3.81Å; F553-T605 HydrophobicContact CZ-CG2 3.77Å; F553-F606 HydrophobicContact CB-CE1 4.46Å; F553-F606 AromaticContact CD2-CD1 3.76Å; F553-F606 HydrophobicContact CD2-CD1 3.76Å; F553-F606 AromaticContact CD2-CE1 3.68Å; F553-F606 HydrophobicContact CD2-CE1 3.68Å; F553-F606 AromaticContact CE2-CD1 3.65Å; F553-F606 HydrophobicContact CE2-CD1 3.65Å; F553-F606 HydrophobicContact CE2-CE1 4.04Å; F553-F606 HydrophobicContact CG-CD1 4.46Å; F553-F606 HydrophobicContact CG-CE1 4.02Å; F553-F606 HydrophobicContact CZ-CD1 4.26Å; F553-A609 HydrophobicContact CE2-CB 3.61Å; F553-A609 HydrophobicContact CZ-CB 3.71Å; F553-I631 HydrophobicContact CD2-CD1 4.35Å; F553-I631 HydrophobicContact CD2-CG1 3.77Å; F553-I631 HydrophobicContact CE2-CD1 4.13Å; F553-I631 HydrophobicContact CE2-CG1 4.06Å
554A89.1Confident84.6Confident39 Ų3958.2 Ų58.232%0.32231%0.306SS..  trans-84.9115.7171.800000108.8S628 T629 Q630A554-S628 WeakPolarHBondContact CB-O 3.26Å; A554-T629 PolarHBondContact N-O 2.97Å; A554-Q630 HydrophobicContact CB-CB 4.31Å; A554-Q630 HydrophobicContact CB-CG 4.19Å
555L89.7Confident84.7Confident33 Ų3363 Ų6317%0.17332%0.32CS..  trans-70.1130.4178.5-172.466.4000109.4F553 L559 Y563 Y583F553-L555 HydrophobicContact CE1-CB 4.47Å; F553-L555 HydrophobicContact CE1-CD1 3.95Å; L555-L559 HydrophobicContact CD1-CB 3.82Å; L555-L559 HydrophobicContact CD1-CD1 3.94Å; L555-L559 HydrophobicContact CD2-CB 4.17Å; L555-L559 HydrophobicContact CG-CB 3.92Å; L555-Y563 HydrophobicContact CD2-CD2 4.41Å; L555-Y563 HydrophobicContact CD2-CG 4.06Å; L555-Y583 HydrophobicContact CD1-CD1 4.13Å; L555-Y583 HydrophobicContact CD1-CE1 3.7Å
556P90.4Very high84.8Confident9 Ų962.1 Ų62.16%0.05832%0.317CS..  trans-57.7143.8174-26.836.8000111.9E558 L559 E560 A609 L612P556-E558 WeakPolarHBondContact CB-OE2 3.34Å; P556-E558 PolarHBondContact O-N 3.28Å; P556-E558 VanDerWaalsContact O-N 3.16Å; P556-L559 PolarHBondContact O-N 3.42Å; P556-E560 PolarHBondContact O-N 3.33Å; P556-A609 HydrophobicContact CG-CB 3.74Å; P556-L612 HydrophobicContact CB-CD1 3.68Å; P556-L612 HydrophobicContact CG-CD1 4.06Å
557S89.8Confident85.1Confident94 Ų9462.4 Ų62.466%0.65732%0.318SS*.Hα-helixtrans-59.4-31.2-173.857.40000112.5L559 E560S557-L559 PolarHBondContact O-N 3.45Å; S557-E560 WeakPolarHBondContact O-CB 3.34Å; S557-E560 PolarHBondContact O-N 3.44Å
558E89.6Confident85.5Confident86 Ų8663.7 Ų63.740%0.40234%0.335SS..Hα-helixtrans-64-26.7176.9-58.685.9168.700112.8L533 P556L533-E558 WeakPolarHBondContact CD2-O 3.48Å; P556-E558 WeakPolarHBondContact CB-OE2 3.34Å; P556-E558 PolarHBondContact O-N 3.28Å; P556-E558 VanDerWaalsContact O-N 3.16Å
559L90.6Very high86.3Confident33 Ų3358.1 Ų58.117%0.17331%0.309CS..Hα-helixtrans-94.9-18.9-179.6-58.2-175.5000113L533 L555 P556 S557 R561 S562 Y563 T605 M608L533-L559 HydrophobicContact CD2-CD2 3.78Å; L555-L559 HydrophobicContact CD1-CB 3.82Å; L555-L559 HydrophobicContact CD1-CD1 3.94Å; L555-L559 HydrophobicContact CD2-CB 4.17Å; L555-L559 HydrophobicContact CG-CB 3.92Å; P556-L559 PolarHBondContact O-N 3.42Å; S557-L559 PolarHBondContact O-N 3.45Å; L559-R561 PolarHBondContact O-N 3.29Å; L559-S562 PolarHBondContact O-N 3.43Å; L559-Y563 PolarHBondContact O-N 3.2Å; L559-Y563 VanDerWaalsContact O-N 3.11Å; L559-T605 HydrophobicContact CD1-CG2 4.27Å; L559-M608 HydrophobicContact CD1-CE 4.37Å; L559-M608 HydrophobicContact CD2-CE 4.35Å
560E90.2Very high87.5Confident63 Ų6351.2 Ų51.229%0.29428%0.277SS..Hα-helixtrans-59.2-42.4-173.7-173.360.2-147.700112.4P556 S557 S562 Y563 Q564P556-E560 PolarHBondContact O-N 3.33Å; S557-E560 WeakPolarHBondContact O-CB 3.34Å; S557-E560 PolarHBondContact O-N 3.44Å; E560-S562 VanDerWaalsContact C-N 3.32Å; E560-S562 PolarHBondContact O-N 2.95Å; E560-Y563 WeakPolarHBondContact O-CB 3.43Å; E560-Y563 PolarHBondContact O-N 3.17Å; E560-Q564 HydrophobicContact CG-CG 4.47Å; E560-Q564 WeakPolarHBondContact O-CG 3.27Å; E560-Q564 PolarHBondContact O-N 3.13Å; E560-Q564 PolarHBondContact OE1-NE2 3.09Å
561R90.6Very high88.9Confident81 Ų8152.7 Ų52.731%0.30629%0.291SS..Hα-helixtrans-59.8-43.1178.6-170.8178.7-174179.45.1111.9E529 L531 D532 L559 R565E529-R561 IonicContact OE2-NH2 2.83Å; E529-R561 PolarHBondContact OE2-NH2 3.09Å; L531-R561 HydrophobicContact CD2-CG 4.4Å; D532-R561 IonicContact OD1-NH1 2.7Å; D532-R561 IonicContact OD2-CZ 2.81Å; D532-R561 IonicContact OD2-NH1 3.53Å; D532-R561 PolarHBondContact OD2-NH1 3.46Å; L559-R561 PolarHBondContact O-N 3.29Å; R561-R565 WeakPolarHBondContact O-CB 3.24Å; R561-R565 VanDerWaalsContact O-CG 3.23Å; R561-R565 WeakPolarHBondContact O-CG 3.15Å; R561-R565 PolarHBondContact O-N 3.02Å; R561-R565 VanDerWaalsContact O-N 3.09Å
562S90.6Very high90Very high3 Ų354.7 Ų54.72%0.02131%0.305CS..Hα-helixtrans-67.1-42.2179.4-61.30000111.3L559 E560 F566L559-S562 PolarHBondContact O-N 3.43Å; E560-S562 VanDerWaalsContact C-N 3.32Å; E560-S562 PolarHBondContact O-N 2.95Å; S562-F566 WeakPolarHBondContact O-CB 3.31Å; S562-F566 PolarHBondContact O-N 3.26Å
563Y90.7Very high90.8Very high67 Ų6755.2 Ų55.226%0.26330%0.296SS..Hα-helixtrans-57.1-51.3174.3165.6-92.1000112.2L555 L559 E560 T567 W581L555-Y563 HydrophobicContact CD2-CD2 4.41Å; L555-Y563 HydrophobicContact CD2-CG 4.06Å; L559-Y563 PolarHBondContact O-N 3.2Å; L559-Y563 VanDerWaalsContact O-N 3.11Å; E560-Y563 WeakPolarHBondContact O-CB 3.43Å; E560-Y563 PolarHBondContact O-N 3.17Å; Y563-T567 VanDerWaalsContact O-CB 3.32Å; Y563-T567 WeakPolarHBondContact O-CB 3.37Å; Y563-T567 PolarHBondContact O-N 3.33Å; Y563-T567 PolarHBondContact O-OG1 3.32Å; Y563-W581 AromaticContact CD2-CD2 3.69Å; Y563-W581 HydrophobicContact CD2-CD2 3.69Å; Y563-W581 AromaticContact CD2-CE2 3.38Å; Y563-W581 HydrophobicContact CD2-CE3 4.07Å; Y563-W581 HydrophobicContact CD2-CG 4.21Å; Y563-W581 AromaticContact CD2-CH2 3.9Å; Y563-W581 HydrophobicContact CD2-CH2 3.9Å; Y563-W581 AromaticContact CD2-CZ2 3.52Å; Y563-W581 HydrophobicContact CD2-CZ2 3.52Å; Y563-W581 HydrophobicContact CD2-CZ3 4.16Å; Y563-W581 AromaticContact CD2-NE1 3.76Å; Y563-W581 AromaticContact CE2-CD1 3.48Å; Y563-W581 VanDerWaalsContact CE2-CD1 3.48Å; Y563-W581 AromaticContact CE2-CD2 3.74Å; Y563-W581 HydrophobicContact CE2-CD2 3.74Å; Y563-W581 AromaticContact CE2-CE2 3.35Å; Y563-W581 AromaticContact CE2-CG 3.82Å; Y563-W581 HydrophobicContact CE2-CG 3.82Å; Y563-W581 AromaticContact CE2-CZ2 3.89Å; Y563-W581 HydrophobicContact CE2-CZ2 3.89Å; Y563-W581 AromaticContact CE2-NE1 3.18Å; Y563-W581 HydrophobicContact CG-CZ2 4.39Å
564Q90.9Very high90.8Very high109 Ų10956.5 Ų56.551%0.50930%0.302SS..Hα-helixtrans-64.5-46.2-177.2-69.3177.6200111.7E560 T567 A568E560-Q564 HydrophobicContact CG-CG 4.47Å; E560-Q564 WeakPolarHBondContact O-CG 3.27Å; E560-Q564 PolarHBondContact O-N 3.13Å; E560-Q564 PolarHBondContact OE1-NE2 3.09Å; Q564-T567 PolarHBondContact O-N 3.3Å; Q564-A568 WeakPolarHBondContact O-CB 3.38Å; Q564-A568 PolarHBondContact O-N 3.36Å
565R90.6Very high90.8Very high124 Ų12460.2 Ų60.247%0.46833%0.325SS..Hα-helixtrans-63.4-44.2-179.5-70.2-67.9-175.1171.33.3112F521 L531 R561 F569F521-R565 HydrophobicContact CZ-CB 4.38Å; L531-R565 HydrophobicContact CD2-CB 4.49Å; L531-R565 HydrophobicContact CD2-CG 4.33Å; R561-R565 WeakPolarHBondContact O-CB 3.24Å; R561-R565 VanDerWaalsContact O-CG 3.23Å; R561-R565 WeakPolarHBondContact O-CG 3.15Å; R561-R565 PolarHBondContact O-N 3.02Å; R561-R565 VanDerWaalsContact O-N 3.09Å; R565-F569 WeakPolarHBondContact O-CB 3.45Å; R565-F569 PolarHBondContact O-N 2.84Å
566F92.6Very high90.8Very high0 Ų062.9 Ų62.90%036%0.361CS..Hα-helixtrans-66.6-41.7176.9-176.2-95.9000111.9L517 F521 F535 I537 V539 S562 A568 F569 Y570 L579 W581L517-F566 HydrophobicContact CD2-CE2 4.46Å; L517-F566 HydrophobicContact CD2-CZ 3.93Å; L517-F566 HydrophobicContact CG-CZ 4.46Å; F521-F566 AromaticContact CD1-CD2 3.97Å; F521-F566 HydrophobicContact CD1-CD2 3.97Å; F521-F566 AromaticContact CD2-CD2 3.96Å; F521-F566 HydrophobicContact CD2-CD2 3.96Å; F521-F566 HydrophobicContact CE1-CB 4.4Å; F521-F566 HydrophobicContact CE1-CD2 4.09Å; F521-F566 HydrophobicContact CE2-CB 4.29Å; F521-F566 HydrophobicContact CE2-CD2 4.09Å; F521-F566 AromaticContact CG-CD2 3.89Å; F521-F566 HydrophobicContact CG-CD2 3.89Å; F521-F566 HydrophobicContact CG-CE2 4.34Å; F521-F566 HydrophobicContact CZ-CB 3.98Å; F521-F566 HydrophobicContact CZ-CD2 4.15Å; F535-F566 HydrophobicContact CE1-CB 3.85Å; F535-F566 AromaticContact CE1-CD2 4Å; F535-F566 HydrophobicContact CE1-CD2 4Å; F535-F566 AromaticContact CE1-CG 3.95Å; F535-F566 HydrophobicContact CE1-CG 3.95Å; F535-F566 HydrophobicContact CZ-CB 4.17Å; F535-F566 HydrophobicContact CZ-CG 4.38Å; I537-F566 HydrophobicContact CD1-CD1 3.67Å; I537-F566 HydrophobicContact CD1-CE1 3.61Å; I537-F566 HydrophobicContact CD1-CG 4.34Å; I537-F566 HydrophobicContact CD1-CZ 4.26Å; I537-F566 HydrophobicContact CG1-CE1 4.24Å; I537-F566 HydrophobicContact CG1-CZ 4.45Å; I537-F566 HydrophobicContact CG2-CD1 4.31Å; I537-F566 HydrophobicContact CG2-CD2 3.77Å; I537-F566 HydrophobicContact CG2-CE1 3.9Å; I537-F566 HydrophobicContact CG2-CE2 3.31Å; I537-F566 HydrophobicContact CG2-CG 4.24Å; I537-F566 HydrophobicContact CG2-CZ 3.37Å; V539-F566 HydrophobicContact CG2-CE1 4.04Å; V539-F566 HydrophobicContact CG2-CZ 3.8Å; S562-F566 WeakPolarHBondContact O-CB 3.31Å; S562-F566 PolarHBondContact O-N 3.26Å; F566-A568 VanDerWaalsContact C-N 3.34Å; F566-A568 PolarHBondContact O-N 3.42Å; F566-F569 HydrophobicContact CD2-CD1 4.29Å; F566-F569 HydrophobicContact CE2-CD1 4.17Å; F566-F569 HydrophobicContact CE2-CE1 4.44Å; F566-F569 PolarHBondContact O-N 2.9Å; F566-Y570 HydrophobicContact CE1-CD2 4.3Å; F566-Y570 HydrophobicContact CZ-CD2 4.16Å; F566-Y570 WeakPolarHBondContact O-CB 3.48Å; F566-Y570 PolarHBondContact O-N 3.31Å; F566-L579 HydrophobicContact CD1-CD1 4.16Å; F566-L579 HydrophobicContact CE1-CD1 3.95Å; F566-W581 HydrophobicContact CB-CH2 4.46Å; F566-W581 AromaticContact CD1-CH2 3.91Å; F566-W581 HydrophobicContact CD1-CH2 3.91Å; F566-W581 AromaticContact CD1-CZ2 3.98Å; F566-W581 HydrophobicContact CD1-CZ2 3.98Å
567T92.4Very high90.8Very high43 Ų4370.1 Ų70.126%0.26439%0.387SS..Hα-helixtrans-60.7-43.8178.8-60.20000111.5Y563 Q564 Y570 A571 W581Y563-T567 VanDerWaalsContact O-CB 3.32Å; Y563-T567 WeakPolarHBondContact O-CB 3.37Å; Y563-T567 PolarHBondContact O-N 3.33Å; Y563-T567 PolarHBondContact O-OG1 3.32Å; Q564-T567 PolarHBondContact O-N 3.3Å; T567-Y570 PolarHBondContact O-N 2.85Å; T567-A571 VanDerWaalsContact O-CB 3.31Å; T567-A571 WeakPolarHBondContact O-CB 3.47Å; T567-A571 PolarHBondContact O-N 2.85Å; T567-W581 WeakPolarHBondContact OG1-CZ2 3.41Å
568A91.3Very high90.7Very high63 Ų6374.8 Ų74.852%0.52140%0.396SS..Hα-helixtrans-63.4-46175.900000112.3Q564 F566 Y570 A571 S572Q564-A568 WeakPolarHBondContact O-CB 3.38Å; Q564-A568 PolarHBondContact O-N 3.36Å; F566-A568 VanDerWaalsContact C-N 3.34Å; F566-A568 PolarHBondContact O-N 3.42Å; A568-Y570 VanDerWaalsContact C-N 3.34Å; A568-Y570 PolarHBondContact O-N 3.14Å; A568-A571 PolarHBondContact O-N 2.97Å; A568-S572 PolarHBondContact O-N 3.34Å
569F92.4Very high90.7Very high4 Ų472.7 Ų72.72%0.01839%0.387CS..Hα-helixtrans-59.8-42.3175.9166.8-96.8000112.6L517 Q520 F521 H524 R565 F566 S572 R573L517-F569 HydrophobicContact CD1-CE1 3.8Å; L517-F569 HydrophobicContact CD1-CZ 4.41Å; L517-F569 HydrophobicContact CG-CE1 4.49Å; Q520-F569 HydrophobicContact CB-CZ 4.14Å; F521-F569 HydrophobicContact CB-CD1 4.26Å; F521-F569 HydrophobicContact CB-CE1 3.83Å; F521-F569 HydrophobicContact CB-CZ 4.07Å; F521-F569 HydrophobicContact CD2-CB 3.93Å; F521-F569 AromaticContact CD2-CD1 3.54Å; F521-F569 HydrophobicContact CD2-CD1 3.54Å; F521-F569 HydrophobicContact CD2-CD2 4.01Å; F521-F569 AromaticContact CD2-CE1 3.98Å; F521-F569 HydrophobicContact CD2-CE1 3.98Å; F521-F569 HydrophobicContact CD2-CE2 4.38Å; F521-F569 AromaticContact CD2-CG 3.55Å; F521-F569 HydrophobicContact CD2-CG 3.55Å; F521-F569 HydrophobicContact CD2-CZ 4.37Å; F521-F569 HydrophobicContact CE2-CB 3.91Å; F521-F569 HydrophobicContact CE2-CD1 4.3Å; F521-F569 HydrophobicContact CE2-CG 4.07Å; F521-F569 HydrophobicContact CG-CD1 4.26Å; F521-F569 HydrophobicContact CG-CE1 4.34Å; H524-F569 HydrophobicContact CB-CD2 3.91Å; H524-F569 HydrophobicContact CB-CE2 3.7Å; H524-F569 AromaticContact CD2-CD2 3.87Å; H524-F569 AromaticContact CG-CD2 3.66Å; H524-F569 AromaticContact CG-CE2 3.92Å; R565-F569 WeakPolarHBondContact O-CB 3.45Å; R565-F569 PolarHBondContact O-N 2.84Å; F566-F569 HydrophobicContact CD2-CD1 4.29Å; F566-F569 HydrophobicContact CE2-CD1 4.17Å; F566-F569 HydrophobicContact CE2-CE1 4.44Å; F566-F569 PolarHBondContact O-N 2.9Å; F569-S572 PolarHBondContact O-OG 3.12Å; F569-R573 VanDerWaalsContact CE2-CZ 3.4Å; F569-R573 PolarHBondContact O-N 2.88Å
570Y93.8Very high90.7Very high14 Ų1474.9 Ų74.96%0.05540%0.402CS..Hα-helixtrans-68.2-44.7179.1-169.5-91.8000111.3L517 V539 F566 T567 A568 S572 R573 H574 R577 L579L517-Y570 HydrophobicContact CD2-CD2 3.97Å; L517-Y570 HydrophobicContact CD2-CE2 3.91Å; V539-Y570 HydrophobicContact CG1-CE2 3.83Å; V539-Y570 HydrophobicContact CG2-CD2 4.49Å; V539-Y570 HydrophobicContact CG2-CE2 4.22Å; F566-Y570 HydrophobicContact CE1-CD2 4.3Å; F566-Y570 HydrophobicContact CZ-CD2 4.16Å; F566-Y570 WeakPolarHBondContact O-CB 3.48Å; F566-Y570 PolarHBondContact O-N 3.31Å; T567-Y570 PolarHBondContact O-N 2.85Å; A568-Y570 VanDerWaalsContact C-N 3.34Å; A568-Y570 PolarHBondContact O-N 3.14Å; Y570-S572 VanDerWaalsContact C-N 3.31Å; Y570-S572 PolarHBondContact O-N 3.15Å; Y570-R573 PolarHBondContact O-N 3.35Å; Y570-H574 HydrophobicContact CD1-CB 4.32Å; Y570-H574 AromaticContact CD2-CD2 3.72Å; Y570-H574 HydrophobicContact CE1-CB 3.91Å; Y570-H574 AromaticContact CE2-CD2 3.39Å; Y570-H574 WeakPolarHBondContact CE2-CD2 3.5Å; Y570-H574 AromaticContact CZ-CD2 3.6Å; Y570-H574 PolarHBondContact O-N 3.3Å; Y570-R577 HydrophobicContact CE1-CB 3.95Å; Y570-R577 WeakPolarHBondContact OH-CD 3.44Å; Y570-L579 HydrophobicContact CD1-CD1 3.86Å; Y570-L579 HydrophobicContact CD1-CD2 3.8Å; Y570-L579 HydrophobicContact CD1-CG 3.72Å; Y570-L579 HydrophobicContact CD2-CD2 4.4Å; Y570-L579 HydrophobicContact CE1-CD2 3.7Å; Y570-L579 HydrophobicContact CE1-CG 4.04Å; Y570-L579 HydrophobicContact CE2-CD2 4.32Å; Y570-L579 HydrophobicContact CG-CD1 3.86Å; Y570-L579 HydrophobicContact CG-CD2 4.15Å; Y570-L579 HydrophobicContact CG-CG 4.19Å
571A92Very high90.6Very high61 Ų6174.1 Ų74.150%0.50440%0.396SS..Hα-helixtrans-62-37.1178.900000112.4T567 A568 R573T567-A571 VanDerWaalsContact O-CB 3.31Å; T567-A571 WeakPolarHBondContact O-CB 3.47Å; T567-A571 PolarHBondContact O-N 2.85Å; A568-A571 PolarHBondContact O-N 2.97Å; A571-R573 VanDerWaalsContact C-N 3.29Å; A571-R573 PolarHBondContact O-N 3.3Å
572S90.7Very high90.6Very high94 Ų9472.1 Ų72.166%0.65739%0.392SS*.Hα-helixtrans-69.6-24.8178.8750000113.4A568 F569 Y570A568-S572 PolarHBondContact O-N 3.34Å; F569-S572 PolarHBondContact O-OG 3.12Å; Y570-S572 VanDerWaalsContact C-N 3.31Å; Y570-S572 PolarHBondContact O-N 3.15Å
573R89.9Confident90.5Very high112 Ų11273.8 Ų73.842%0.42340%0.398SS..Hα-helixtrans-97.9-27.3179.9-69.4-171.3177.6-150.6-0.5113.9F569 Y570 A571F569-R573 VanDerWaalsContact CE2-CZ 3.4Å; F569-R573 PolarHBondContact O-N 2.88Å; Y570-R573 PolarHBondContact O-N 3.35Å; A571-R573 VanDerWaalsContact C-N 3.29Å; A571-R573 PolarHBondContact O-N 3.3Å
574H89.6Confident90.2Very high55 Ų5573.1 Ų73.126%0.25540%0.397SS..SBendtrans-126.780.2-173.4-62.7-59.8000111.1Y570 R577Y570-H574 HydrophobicContact CD1-CB 4.32Å; Y570-H574 AromaticContact CD2-CD2 3.72Å; Y570-H574 HydrophobicContact CE1-CB 3.91Å; Y570-H574 AromaticContact CE2-CD2 3.39Å; Y570-H574 WeakPolarHBondContact CE2-CD2 3.5Å; Y570-H574 AromaticContact CZ-CD2 3.6Å; Y570-H574 PolarHBondContact O-N 3.3Å; H574-R577 HydrophobicContact CB-CB 4.39Å; H574-R577 HydrophobicContact CB-CG 4.31Å; H574-R577 PolarHBondContact O-N 3.15Å
575S89.6Confident89.9Confident116 Ų11669.4 Ų69.481%0.81138%0.381SS*.THydrogen-bonded Turntrans-61.4134.417357.70000111.2
576G87.8Confident89.9Confident90 Ų9065.8 Ų65.893%0.92837%0.374SS*.THydrogen-bonded Turntrans83.98.5177.100000115.3
577R91.1Very high89.8Confident160 Ų16071.5 Ų71.560%0.60440%0.399SS*.  trans-109.4145.2173.3-60.9-168.4-174.6173.9-0.5111.3Y570 H574Y570-R577 HydrophobicContact CE1-CB 3.95Å; Y570-R577 WeakPolarHBondContact OH-CD 3.44Å; H574-R577 HydrophobicContact CB-CB 4.39Å; H574-R577 HydrophobicContact CB-CG 4.31Å; H574-R577 PolarHBondContact O-N 3.15Å
578K88Confident89.8Confident193 Ų19370.5 Ų70.584%0.83940%0.397SS*.  trans-118.3129.5175.5-175.2178.4179.3-179.20110
579L90.4Very high90Very high41 Ų4172 Ų7222%0.21539%0.393CS..  trans-82.2136.8173.3-66.7176.2000110.4V539 F566 Y570 W581V539-L579 HydrophobicContact CG1-CD2 4.16Å; F566-L579 HydrophobicContact CD1-CD1 4.16Å; F566-L579 HydrophobicContact CE1-CD1 3.95Å; Y570-L579 HydrophobicContact CD1-CD1 3.86Å; Y570-L579 HydrophobicContact CD1-CD2 3.8Å; Y570-L579 HydrophobicContact CD1-CG 3.72Å; Y570-L579 HydrophobicContact CD2-CD2 4.4Å; Y570-L579 HydrophobicContact CE1-CD2 3.7Å; Y570-L579 HydrophobicContact CE1-CG 4.04Å; Y570-L579 HydrophobicContact CE2-CD2 4.32Å; Y570-L579 HydrophobicContact CG-CD1 3.86Å; Y570-L579 HydrophobicContact CG-CD2 4.15Å; Y570-L579 HydrophobicContact CG-CG 4.19Å; L579-W581 HydrophobicContact CD1-CZ2 4.31Å
580T89.6Confident90Very high80 Ų8073 Ų7349%0.49140%0.399SS..  trans-121.4121.9168.7-56.60000107.3Q549Q549-T580 HydrophobicContact CG-CG2 3.86Å
581W88.8Confident90Very high46 Ų4675.5 Ų75.517%0.17442%0.415CS..  trans-93.1130-171-68.276.3000110.8F535 I537 Y563 F566 T567 L579 Y583F535-W581 HydrophobicContact CZ-CH2 4.21Å; F535-W581 HydrophobicContact CZ-CZ3 4.35Å; I537-W581 HydrophobicContact CD1-CE3 4.08Å; I537-W581 HydrophobicContact CD1-CH2 3.25Å; I537-W581 HydrophobicContact CD1-CZ2 4.05Å; I537-W581 HydrophobicContact CD1-CZ3 3.26Å; Y563-W581 AromaticContact CD2-CD2 3.69Å; Y563-W581 HydrophobicContact CD2-CD2 3.69Å; Y563-W581 AromaticContact CD2-CE2 3.38Å; Y563-W581 HydrophobicContact CD2-CE3 4.07Å; Y563-W581 HydrophobicContact CD2-CG 4.21Å; Y563-W581 AromaticContact CD2-CH2 3.9Å; Y563-W581 HydrophobicContact CD2-CH2 3.9Å; Y563-W581 AromaticContact CD2-CZ2 3.52Å; Y563-W581 HydrophobicContact CD2-CZ2 3.52Å; Y563-W581 HydrophobicContact CD2-CZ3 4.16Å; Y563-W581 AromaticContact CD2-NE1 3.76Å; Y563-W581 AromaticContact CE2-CD1 3.48Å; Y563-W581 VanDerWaalsContact CE2-CD1 3.48Å; Y563-W581 AromaticContact CE2-CD2 3.74Å; Y563-W581 HydrophobicContact CE2-CD2 3.74Å; Y563-W581 AromaticContact CE2-CE2 3.35Å; Y563-W581 AromaticContact CE2-CG 3.82Å; Y563-W581 HydrophobicContact CE2-CG 3.82Å; Y563-W581 AromaticContact CE2-CZ2 3.89Å; Y563-W581 HydrophobicContact CE2-CZ2 3.89Å; Y563-W581 AromaticContact CE2-NE1 3.18Å; Y563-W581 HydrophobicContact CG-CZ2 4.39Å; F566-W581 HydrophobicContact CB-CH2 4.46Å; F566-W581 AromaticContact CD1-CH2 3.91Å; F566-W581 HydrophobicContact CD1-CH2 3.91Å; F566-W581 AromaticContact CD1-CZ2 3.98Å; F566-W581 HydrophobicContact CD1-CZ2 3.98Å; T567-W581 WeakPolarHBondContact OG1-CZ2 3.41Å; L579-W581 HydrophobicContact CD1-CZ2 4.31Å; W581-Y583 HydrophobicContact CB-CE1 3.96Å; W581-Y583 HydrophobicContact CB-CE2 3.95Å; W581-Y583 HydrophobicContact CE3-CE1 4.29Å
582L89.8Confident90.1Very high39 Ų3973.3 Ų73.320%0.20440%0.395CS..  trans-109.778.4-177.2-58.7-177.9000110.1F547 H584 L585 S586F547-L582 HydrophobicContact CB-CD1 3.67Å; F547-L582 HydrophobicContact CD2-CD1 4.18Å; F547-L582 HydrophobicContact CG-CD1 4.25Å; L582-H584 VanDerWaalsContact C-N 3.27Å; L582-H584 PolarHBondContact O-N 3.43Å; L582-L585 HydrophobicContact CB-CD1 4.19Å; L582-L585 HydrophobicContact CD1-CD1 3.94Å; L582-L585 PolarHBondContact O-N 3.16Å; L582-S586 PolarHBondContact O-OG 3.44Å
583Y88.3Confident90Very high38 Ų3874.9 Ų74.915%0.14940%0.397CS..G310 helixtrans-63.9-30.2-174.5-58.6-64.8000113.6F553 L555 W581 L585 S586 T605F553-Y583 HydrophobicContact CB-CD2 4.21Å; F553-Y583 HydrophobicContact CD1-CD1 4.24Å; F553-Y583 AromaticContact CD1-CD2 3.45Å; F553-Y583 HydrophobicContact CD1-CD2 3.45Å; F553-Y583 VanDerWaalsContact CD1-CD2 3.45Å; F553-Y583 AromaticContact CD1-CE2 3.97Å; F553-Y583 HydrophobicContact CD1-CE2 3.97Å; F553-Y583 AromaticContact CD1-CG 3.59Å; F553-Y583 HydrophobicContact CD1-CG 3.59Å; F553-Y583 HydrophobicContact CE1-CD1 4.23Å; F553-Y583 HydrophobicContact CE1-CD2 4.23Å; F553-Y583 AromaticContact CE1-CG 3.93Å; F553-Y583 HydrophobicContact CE1-CG 3.93Å; F553-Y583 HydrophobicContact CG-CD2 4.21Å; L555-Y583 HydrophobicContact CD1-CD1 4.13Å; L555-Y583 HydrophobicContact CD1-CE1 3.7Å; W581-Y583 HydrophobicContact CB-CE1 3.96Å; W581-Y583 HydrophobicContact CB-CE2 3.95Å; W581-Y583 HydrophobicContact CE3-CE1 4.29Å; Y583-L585 PolarHBondContact O-N 3.35Å; Y583-S586 WeakPolarHBondContact O-CB 3.39Å; Y583-S586 PolarHBondContact O-N 3.34Å; Y583-T605 HydrophobicContact CD1-CG2 4.46Å
584H83.9Confident89.8Confident54 Ų5472.7 Ų72.725%0.2540%0.398CS..G310 helixtrans-63.9-23.2177.669.3-74.5000114.1S550 L582 F606S550-H584 VanDerWaalsContact CB-ND1 3.3Å; S550-H584 WeakPolarHBondContact CB-ND1 3.39Å; S550-H584 PolarHBondContact OG-ND1 3.13Å; L582-H584 VanDerWaalsContact C-N 3.27Å; L582-H584 PolarHBondContact O-N 3.43Å; H584-F606 HydrophobicContact CB-CE2 3.69Å; H584-F606 HydrophobicContact CB-CZ 3.74Å
585L86.4Confident89.7Confident31 Ų3171 Ų7116%0.16239%0.39CS..G310 helixtrans-94.4-5.5175.5-60.3173.8000112.7F547 L582 Y583F547-L585 HydrophobicContact CB-CD1 4.16Å; F547-L585 HydrophobicContact CD1-CD1 3.59Å; F547-L585 HydrophobicContact CD1-CD2 4.44Å; F547-L585 HydrophobicContact CD2-CD1 3.57Å; F547-L585 HydrophobicContact CE1-CD1 3.75Å; F547-L585 HydrophobicContact CE1-CD2 4.21Å; F547-L585 HydrophobicContact CE2-CD1 3.71Å; F547-L585 HydrophobicContact CG-CD1 3.5Å; F547-L585 VanDerWaalsContact CG-CD1 3.5Å; F547-L585 HydrophobicContact CZ-CD1 3.8Å; L582-L585 HydrophobicContact CB-CD1 4.19Å; L582-L585 HydrophobicContact CD1-CD1 3.94Å; L582-L585 PolarHBondContact O-N 3.16Å; Y583-L585 PolarHBondContact O-N 3.35Å
586S89.6Confident89.5Confident47 Ų4774.8 Ų74.833%0.32939%0.391SS..  trans-86.5148-175.5-60.90000110.7L582 Y583 T605L582-S586 PolarHBondContact O-OG 3.44Å; Y583-S586 WeakPolarHBondContact O-CB 3.39Å; Y583-S586 PolarHBondContact O-N 3.34Å; S586-T605 WeakPolarHBondContact CB-OG1 3.19Å; S586-T605 PolarHBondContact O-N 3.49Å; S586-T605 VanDerWaalsContact O-N 3.14Å; S586-T605 PolarHBondContact O-OG1 3.28Å
587K91.3Very high89.5Confident121 Ų12174.2 Ų74.253%0.52637%0.367SS..EExtended strand (participates in β ladder)trans-139.2152.9-179.764-177.4178-178.90110H476 A603H476-K587 PolarHBondContact O-NZ 2.64Å; K587-A603 CarbonylContact C-O 3.5Å; K587-A603 VanDerWaalsContact CA-O 3.31Å; K587-A603 WeakPolarHBondContact CA-O 3.43Å
588G92.6Very high89.5Confident22 Ų2274.9 Ų74.923%0.22737%0.37CS..EExtended strand (participates in β ladder)trans-149.9177.9177.200000112.1A603G588-A603 PolarHBondContact N-O 2.74Å; G588-A603 PolarHBondContact O-N 3.29Å
589E94.3Very high89.8Confident94 Ų9465.8 Ų65.844%0.43933%0.33SS..EExtended strand (participates in β ladder)trans-116.7128176.1-55.5-158.3145.200110T600 L601 Q602 R681E589-T600 HydrophobicContact CB-CG2 4.09Å; E589-L601 CarbonylContact C-O 3.59Å; E589-L601 VanDerWaalsContact CA-O 3.29Å; E589-L601 WeakPolarHBondContact CA-O 3.49Å; E589-Q602 HydrophobicContact CG-CG 4.34Å; E589-Q602 WeakPolarHBondContact OE1-CG 3.49Å; E589-Q602 PolarHBondContact OE1-NE2 2.77Å; E589-R681 IonicContact OE1-CZ 3.19Å; E589-R681 VanDerWaalsContact OE1-CZ 3.31Å; E589-R681 IonicContact OE1-NE 3.67Å; E589-R681 PolarHBondContact OE1-NE 3.47Å; E589-R681 IonicContact OE1-NH2 2.77Å; E589-R681 PolarHBondContact OE1-NH2 2.94Å; E589-R681 IonicContact OE2-NH2 3.65Å; E589-R681 PolarHBondContact OE2-NH2 3.39Å
590L93.6Very high90Very high25 Ų2565.6 Ų65.613%0.13133%0.33CS..EExtended strand (participates in β ladder)trans-106.6138.4173.6-66.4174.7000109.7T600 L601 M608 L611 L612L590-T600 CarbonylContact O-C 3.57Å; L590-T600 WeakPolarHBondContact O-CA 3.26Å; L590-L601 HydrophobicContact CB-CB 4.38Å; L590-L601 PolarHBondContact N-O 3.17Å; L590-L601 PolarHBondContact O-N 3.01Å; L590-M608 HydrophobicContact CD1-CB 4.17Å; L590-M608 HydrophobicContact CD1-CG 3.84Å; L590-M608 HydrophobicContact CD2-CE 3.84Å; L590-M608 HydrophobicContact CD2-CG 4.25Å; L590-M608 HydrophobicContact CG-CE 4.34Å; L590-M608 HydrophobicContact CG-CG 3.93Å; L590-L611 HydrophobicContact CD1-CB 3.99Å; L590-L611 HydrophobicContact CD1-CD1 3.83Å; L590-L612 HydrophobicContact CD2-CD2 4.1Å; L590-L612 HydrophobicContact CD2-CG 4.4Å
591V93.5Very high90.3Very high66 Ų6661.9 Ų61.940%0.431%0.308SS..EExtended strand (participates in β ladder)trans-103.4121.8173.3178.30000108.5R598V591-R598 HydrophobicContact CG1-CG 3.76Å
592T92.6Very high90.5Very high15 Ų1562.6 Ų62.69%0.09231%0.313CS..  trans-87.4126.8-179.256.60000110.6F595 Y599 L601T592-F595 HydrophobicContact CG2-CD2 4.02Å; T592-F595 HydrophobicContact CG2-CE2 3.75Å; T592-Y599 PolarHBondContact N-O 3.1Å; T592-Y599 WeakPolarHBondContact OG1-CA 3.32Å; T592-Y599 VanDerWaalsContact OG1-CB 3.32Å; T592-Y599 WeakPolarHBondContact OG1-CB 3.31Å; T592-Y599 PolarHBondContact OG1-N 2.87Å; T592-Y599 PolarHBondContact OG1-O 2.61Å; T592-L601 HydrophobicContact CG2-CD1 3.57Å; T592-L601 HydrophobicContact CG2-CG 3.86Å
593N89.9Confident90.7Very high128 Ų12860.8 Ų60.868%0.68430%0.304SS*.  trans-113.1-8175.7-63.8-32.3000112.7
594C85.3Confident90.9Very high65 Ų6559.5 Ų59.544%0.43930%0.3SS..SBendtrans-84.7-9.6-17753.40000114.3L671 L673C594-L671 HydrophobicContact CB-CD2 4.31Å; C594-L673 HydrophobicContact CB-CD2 4.45Å
595F87.7Confident91.2Very high21 Ų2157.3 Ų57.39%0.09229%0.291CS..SBendtrans-106.2162.4-177.6-53.7-46.6000112.3T592 N597 Y599 L648 L671 F672 Y675T592-F595 HydrophobicContact CG2-CD2 4.02Å; T592-F595 HydrophobicContact CG2-CE2 3.75Å; F595-N597 PolarHBondContact O-N 2.93Å; F595-Y599 HydrophobicContact CB-CD2 4.42Å; F595-Y599 HydrophobicContact CB-CE2 4.47Å; F595-Y599 HydrophobicContact CD2-CD2 4.14Å; F595-L648 HydrophobicContact CE2-CD2 3.88Å; F595-L648 HydrophobicContact CZ-CD2 4.04Å; F595-L671 HydrophobicContact CZ-CD1 4.38Å; F595-F672 WeakPolarHBondContact CE1-O 3.44Å; F595-Y675 AromaticContact CD2-CD1 3.89Å; F595-Y675 HydrophobicContact CD2-CD1 3.89Å; F595-Y675 HydrophobicContact CD2-CG 4.34Å; F595-Y675 AromaticContact CE2-CD1 3.97Å; F595-Y675 HydrophobicContact CE2-CD1 3.97Å; F595-Y675 HydrophobicContact CE2-CG 4.17Å; F595-Y675 HydrophobicContact CG-CD1 4.45Å; F595-Y675 HydrophobicContact CZ-CG 4.37Å
596K85.5Confident91.5Very high194 Ų19456.1 Ų56.184%0.84328%0.284SS*.SBendtrans-55.9-35.7178.3-173.7176.4-1781770113.2
597N88.1Confident91.7Very high78 Ų7854 Ų5442%0.41727%0.269SS..SBendtrans-112.2146.7173.1-64.5-36000109.3F595 Y599F595-N597 PolarHBondContact O-N 2.93Å; N597-Y599 HydrophobicContact CB-CD2 4.3Å; N597-Y599 HydrophobicContact CB-CE1 4.47Å; N597-Y599 HydrophobicContact CB-CE2 3.65Å; N597-Y599 PolarHBondContact ND2-OH 3.07Å; N597-Y599 WeakPolarHBondContact O-CD2 3.32Å; N597-Y599 WeakPolarHBondContact O-CE2 3.38Å; N597-Y599 PolarHBondContact O-N 3.13Å
598R91.3Very high91.8Very high174 Ų17448.9 Ų48.966%0.65725%0.247SC*.  trans-79.3110.3173.4-177.1168.7167.3156-0.9109.9V591V591-R598 HydrophobicContact CG1-CG 3.76Å
599Y93.7Very high91.8Very high3 Ų347.9 Ų47.91%0.01224%0.237CC..  trans-103.4145.3175.8-61.1-83.4000111.4T592 F595 N597 Y675 N677 K679 L680 V682T592-Y599 PolarHBondContact N-O 3.1Å; T592-Y599 WeakPolarHBondContact OG1-CA 3.32Å; T592-Y599 VanDerWaalsContact OG1-CB 3.32Å; T592-Y599 WeakPolarHBondContact OG1-CB 3.31Å; T592-Y599 PolarHBondContact OG1-N 2.87Å; T592-Y599 PolarHBondContact OG1-O 2.61Å; F595-Y599 HydrophobicContact CB-CD2 4.42Å; F595-Y599 HydrophobicContact CB-CE2 4.47Å; F595-Y599 HydrophobicContact CD2-CD2 4.14Å; N597-Y599 HydrophobicContact CB-CD2 4.3Å; N597-Y599 HydrophobicContact CB-CE1 4.47Å; N597-Y599 HydrophobicContact CB-CE2 3.65Å; N597-Y599 PolarHBondContact ND2-OH 3.07Å; N597-Y599 WeakPolarHBondContact O-CD2 3.32Å; N597-Y599 WeakPolarHBondContact O-CE2 3.38Å; N597-Y599 PolarHBondContact O-N 3.13Å; Y599-Y675 HydrophobicContact CD1-CE1 4.28Å; Y599-Y675 AromaticContact CD2-CD1 3.71Å; Y599-Y675 HydrophobicContact CD2-CD1 3.71Å; Y599-Y675 AromaticContact CD2-CE1 3.84Å; Y599-Y675 HydrophobicContact CD2-CE1 3.84Å; Y599-Y675 HydrophobicContact CE1-CE1 4.47Å; Y599-Y675 AromaticContact CE2-CD1 3.7Å; Y599-Y675 HydrophobicContact CE2-CD1 3.7Å; Y599-Y675 HydrophobicContact CE2-CE1 4.01Å; Y599-Y675 HydrophobicContact CG-CD1 4.33Å; Y599-Y675 AromaticContact CG-CE1 3.99Å; Y599-Y675 HydrophobicContact CG-CE1 3.99Å; Y599-N677 HydrophobicContact CD1-CB 4.38Å; Y599-N677 HydrophobicContact CE1-CB 3.86Å; Y599-N677 PolarHBondContact OH-N 3.3Å; Y599-N677 VanDerWaalsContact OH-N 3.15Å; Y599-N677 PolarHBondContact OH-O 3.39Å; Y599-K679 WeakPolarHBondContact CD1-O 3.35Å; Y599-K679 WeakPolarHBondContact CE1-O 3.3Å; Y599-L680 CarbonylContact C-O 3.42Å; Y599-L680 VanDerWaalsContact CA-O 3.29Å; Y599-L680 WeakPolarHBondContact CA-O 3.42Å; Y599-L680 HydrophobicContact CD1-CD2 4.37Å; Y599-L680 HydrophobicContact CE1-CD2 4.19Å; Y599-V682 HydrophobicContact CD1-CG2 4.45Å
600T94.6Very high91.8Very high36 Ų3643.4 Ų43.422%0.22122%0.216CC..EExtended strand (participates in β ladder)trans-102.6114.3168.9-58.10000109.2E589 L590 L680 R681 V682E589-T600 HydrophobicContact CB-CG2 4.09Å; L590-T600 CarbonylContact O-C 3.57Å; L590-T600 WeakPolarHBondContact O-CA 3.26Å; T600-L680 PolarHBondContact N-O 3.35Å; T600-R681 HydrophobicContact CG2-CG 4.29Å; T600-R681 CarbonylContact O-C 3.35Å; T600-R681 WeakPolarHBondContact O-CA 3.46Å; T600-V682 PolarHBondContact O-N 3.1Å
601L94.9Very high91.9Very high3 Ų343.2 Ų43.22%0.01622%0.215CC..EExtended strand (participates in β ladder)trans-97.3122-179.7-54.9178.9000110.1E589 L590 T592 L611 L648 V682 I684E589-L601 CarbonylContact C-O 3.59Å; E589-L601 VanDerWaalsContact CA-O 3.29Å; E589-L601 WeakPolarHBondContact CA-O 3.49Å; L590-L601 HydrophobicContact CB-CB 4.38Å; L590-L601 PolarHBondContact N-O 3.17Å; L590-L601 PolarHBondContact O-N 3.01Å; T592-L601 HydrophobicContact CG2-CD1 3.57Å; T592-L601 HydrophobicContact CG2-CG 3.86Å; L601-L611 HydrophobicContact CD1-CD1 4.2Å; L601-L648 HydrophobicContact CD1-CD1 3.77Å; L601-L648 HydrophobicContact CD1-CD2 4.02Å; L601-L648 HydrophobicContact CD2-CD1 4.4Å; L601-L648 HydrophobicContact CD2-CD2 4.42Å; L601-V682 CarbonylContact C-O 3.58Å; L601-V682 WeakPolarHBondContact CA-O 3.47Å; L601-V682 HydrophobicContact CD2-CB 4.05Å; L601-I684 HydrophobicContact CB-CD1 4.21Å; L601-I684 HydrophobicContact CB-CG1 4.47Å; L601-I684 HydrophobicContact CD1-CD1 4.33Å
602Q93.8Very high91.9Very high61 Ų6141.2 Ų41.229%0.28520%0.202SC..EExtended strand (participates in β ladder)trans-87.7114.2168.6-52.3-174.5-51.600108.4E589 R681 V682 N683 I684 N685E589-Q602 HydrophobicContact CG-CG 4.34Å; E589-Q602 WeakPolarHBondContact OE1-CG 3.49Å; E589-Q602 PolarHBondContact OE1-NE2 2.77Å; Q602-R681 HydrophobicContact CG-CG 4.48Å; Q602-V682 PolarHBondContact N-O 3.45Å; Q602-N683 HydrophobicContact CB-CB 4.34Å; Q602-N683 PolarHBondContact O-OD1 2.94Å; Q602-I684 WeakPolarHBondContact O-CG1 3.44Å; Q602-I684 PolarHBondContact O-N 3.36Å; Q602-N685 PolarHBondContact O-N 3.3Å; Q602-N685 VanDerWaalsContact O-N 3.08Å
603A93.7Very high91.9Very high1 Ų142.8 Ų42.81%0.00821%0.208CC..EExtended strand (participates in β ladder)trans-129.6152-167.100000111.2K587 G588 Q607 M608 I684K587-A603 CarbonylContact C-O 3.5Å; K587-A603 VanDerWaalsContact CA-O 3.31Å; K587-A603 WeakPolarHBondContact CA-O 3.43Å; G588-A603 PolarHBondContact N-O 2.74Å; G588-A603 PolarHBondContact O-N 3.29Å; A603-Q607 HydrophobicContact CB-CB 3.93Å; A603-M608 HydrophobicContact CB-CG 3.8Å; A603-I684 HydrophobicContact CB-CD1 3.89Å; A603-I684 HydrophobicContact CB-CG1 3.94Å
604S92.4Very high92.1Very high11 Ų1137.2 Ų37.28%0.07718%0.177CC..EExtended strand (participates in β ladder)trans-71158.1164.571.70000110.2F606 Q607 M608S604-F606 PolarHBondContact O-N 2.72Å; S604-Q607 WeakPolarHBondContact O-CB 3.37Å; S604-Q607 PolarHBondContact O-N 3.45Å; S604-Q607 WeakPolarHBondContact OG-CG 3.43Å; S604-Q607 PolarHBondContact OG-N 3.01Å; S604-M608 WeakPolarHBondContact O-CG 3.35Å; S604-M608 PolarHBondContact O-N 3.49Å
605T91.5Very high92.4Very high8 Ų839.8 Ų39.85%0.04919%0.187CC..Hα-helixtrans-59.6-30.9178.5-58.80000112.7F553 L559 Y583 S586 M608 A609F553-T605 HydrophobicContact CE1-CG2 3.81Å; F553-T605 HydrophobicContact CZ-CG2 3.77Å; L559-T605 HydrophobicContact CD1-CG2 4.27Å; Y583-T605 HydrophobicContact CD1-CG2 4.46Å; S586-T605 WeakPolarHBondContact CB-OG1 3.19Å; S586-T605 PolarHBondContact O-N 3.49Å; S586-T605 VanDerWaalsContact O-N 3.14Å; S586-T605 PolarHBondContact O-OG1 3.28Å; T605-M608 PolarHBondContact O-N 3.37Å; T605-A609 PolarHBondContact O-N 3.45Å
606F91.6Very high92.6Very high6 Ų644.3 Ų44.33%0.02622%0.216CC..Hα-helixtrans-67.8-41.5173.3-64.5-21.6000112.7F553 H584 S604 M608 A609 I610 I631 I635 V639F553-F606 HydrophobicContact CB-CE1 4.46Å; F553-F606 AromaticContact CD2-CD1 3.76Å; F553-F606 HydrophobicContact CD2-CD1 3.76Å; F553-F606 AromaticContact CD2-CE1 3.68Å; F553-F606 HydrophobicContact CD2-CE1 3.68Å; F553-F606 AromaticContact CE2-CD1 3.65Å; F553-F606 HydrophobicContact CE2-CD1 3.65Å; F553-F606 HydrophobicContact CE2-CE1 4.04Å; F553-F606 HydrophobicContact CG-CD1 4.46Å; F553-F606 HydrophobicContact CG-CE1 4.02Å; F553-F606 HydrophobicContact CZ-CD1 4.26Å; H584-F606 HydrophobicContact CB-CE2 3.69Å; H584-F606 HydrophobicContact CB-CZ 3.74Å; S604-F606 PolarHBondContact O-N 2.72Å; F606-M608 VanDerWaalsContact C-N 3.3Å; F606-M608 PolarHBondContact O-N 2.91Å; F606-A609 PolarHBondContact O-N 3.27Å; F606-I610 WeakPolarHBondContact O-CG1 3.49Å; F606-I610 PolarHBondContact O-N 3.19Å; F606-I631 HydrophobicContact CB-CD1 3.97Å; F606-I631 HydrophobicContact CD1-CD1 4.08Å; F606-I631 HydrophobicContact CD1-CG1 4.22Å; F606-I631 HydrophobicContact CG-CD1 4.17Å; F606-I635 HydrophobicContact CD2-CG2 3.79Å; F606-I635 HydrophobicContact CE2-CG2 3.95Å; F606-V639 HydrophobicContact CB-CG2 4.18Å
607Q93.4Very high92.9Very high3 Ų340 Ų401%0.01420%0.199CC..Hα-helixtrans-62.9-40.4172.9-72.5167.9-17.700111A603 S604 I610 L611 V639 L643 I684A603-Q607 HydrophobicContact CB-CB 3.93Å; S604-Q607 WeakPolarHBondContact O-CB 3.37Å; S604-Q607 PolarHBondContact O-N 3.45Å; S604-Q607 WeakPolarHBondContact OG-CG 3.43Å; S604-Q607 PolarHBondContact OG-N 3.01Å; Q607-I610 PolarHBondContact O-N 3.23Å; Q607-L611 WeakPolarHBondContact O-CB 3.31Å; Q607-L611 VanDerWaalsContact O-CG 3.3Å; Q607-L611 WeakPolarHBondContact O-CG 3.45Å; Q607-L611 PolarHBondContact O-N 2.97Å; Q607-V639 HydrophobicContact CB-CG1 4.32Å; Q607-V639 HydrophobicContact CG-CG1 3.53Å; Q607-L643 HydrophobicContact CG-CD2 4.42Å; Q607-I684 PolarHBondContact NE2-O 2.95Å; Q607-I684 PolarHBondContact OE1-O 3.44Å
608M93.6Very high93Very high13 Ų1341 Ų416%0.06421%0.205CC..Hα-helixtrans-62.3-45.7176.7-64.9172.965.600111.9L559 L590 A603 S604 T605 F606 I610 L611 L612L559-M608 HydrophobicContact CD1-CE 4.37Å; L559-M608 HydrophobicContact CD2-CE 4.35Å; L590-M608 HydrophobicContact CD1-CB 4.17Å; L590-M608 HydrophobicContact CD1-CG 3.84Å; L590-M608 HydrophobicContact CD2-CE 3.84Å; L590-M608 HydrophobicContact CD2-CG 4.25Å; L590-M608 HydrophobicContact CG-CE 4.34Å; L590-M608 HydrophobicContact CG-CG 3.93Å; A603-M608 HydrophobicContact CB-CG 3.8Å; S604-M608 WeakPolarHBondContact O-CG 3.35Å; S604-M608 PolarHBondContact O-N 3.49Å; T605-M608 PolarHBondContact O-N 3.37Å; F606-M608 VanDerWaalsContact C-N 3.3Å; F606-M608 PolarHBondContact O-N 2.91Å; M608-I610 VanDerWaalsContact C-N 3.26Å; M608-I610 PolarHBondContact O-N 3.13Å; M608-L611 PolarHBondContact O-N 3.08Å; M608-L612 HydrophobicContact CB-CD1 4.43Å; M608-L612 WeakPolarHBondContact O-CB 3.46Å; M608-L612 WeakPolarHBondContact O-CG 3.29Å; M608-L612 PolarHBondContact O-N 2.76Å
609A93.6Very high93.1Very high1 Ų135.1 Ų35.11%0.00819%0.19CC..Hα-helixtrans-59-37.6-179.200000113.3F553 P556 T605 F606 Q613 T629F553-A609 HydrophobicContact CE2-CB 3.61Å; F553-A609 HydrophobicContact CZ-CB 3.71Å; P556-A609 HydrophobicContact CG-CB 3.74Å; T605-A609 PolarHBondContact O-N 3.45Å; F606-A609 PolarHBondContact O-N 3.27Å; A609-Q613 WeakPolarHBondContact O-CG 3.37Å; A609-Q613 PolarHBondContact O-NE2 3.04Å; A609-T629 HydrophobicContact CB-CG2 4.12Å
610I94.3Very high93.2Very high0 Ų036 Ų360%019%0.194CC..Hα-helixtrans-72.1-49.7175.6-62.6170.1000110.6F606 Q607 M608 L612 Q613 Y614 L625 T629 I631 L636 V639 L640 L643 L649F606-I610 WeakPolarHBondContact O-CG1 3.49Å; F606-I610 PolarHBondContact O-N 3.19Å; Q607-I610 PolarHBondContact O-N 3.23Å; M608-I610 VanDerWaalsContact C-N 3.26Å; M608-I610 PolarHBondContact O-N 3.13Å; I610-L612 VanDerWaalsContact C-N 3.29Å; I610-L612 PolarHBondContact O-N 2.98Å; I610-Q613 WeakPolarHBondContact O-CB 3.41Å; I610-Q613 PolarHBondContact O-N 2.98Å; I610-Y614 HydrophobicContact CG2-CE2 4.19Å; I610-Y614 WeakPolarHBondContact O-CD2 2.89Å; I610-L625 HydrophobicContact CG2-CD1 4.33Å; I610-L625 HydrophobicContact CG2-CD2 4.38Å; I610-T629 HydrophobicContact CG1-CG2 4.33Å; I610-I631 HydrophobicContact CG1-CD1 4.45Å; I610-L636 HydrophobicContact CD1-CD1 3.49Å; I610-L636 VanDerWaalsContact CD1-CD1 3.49Å; I610-L636 HydrophobicContact CG1-CD1 3.96Å; I610-V639 HydrophobicContact CD1-CB 3.95Å; I610-V639 HydrophobicContact CD1-CG1 3.43Å; I610-V639 VanDerWaalsContact CD1-CG1 3.43Å; I610-L640 HydrophobicContact CD1-CD2 4.27Å; I610-L640 HydrophobicContact CG2-CD2 4.14Å; I610-L643 HydrophobicContact CB-CD1 4.3Å; I610-L643 HydrophobicContact CD1-CD1 4.42Å; I610-L643 HydrophobicContact CG2-CD1 3.96Å; I610-L649 HydrophobicContact CG2-CD1 4.35Å
611L94.4Very high93.1Very high21 Ų2135.8 Ų35.811%0.1119%0.192CC..Hα-helixtrans-64.2-33.3-176.1-71.5173.3000112.6L590 L601 Q607 M608 Q613 Y614 L643 I684L590-L611 HydrophobicContact CD1-CB 3.99Å; L590-L611 HydrophobicContact CD1-CD1 3.83Å; L601-L611 HydrophobicContact CD1-CD1 4.2Å; Q607-L611 WeakPolarHBondContact O-CB 3.31Å; Q607-L611 VanDerWaalsContact O-CG 3.3Å; Q607-L611 WeakPolarHBondContact O-CG 3.45Å; Q607-L611 PolarHBondContact O-N 2.97Å; M608-L611 PolarHBondContact O-N 3.08Å; L611-Q613 VanDerWaalsContact C-N 3.3Å; L611-Q613 PolarHBondContact O-N 2.89Å; L611-Y614 PolarHBondContact O-N 3.01Å; L611-L643 HydrophobicContact CD1-CD2 4.12Å; L611-L643 HydrophobicContact CD2-CD1 4.27Å; L611-L643 HydrophobicContact CD2-CD2 4.25Å; L611-L643 HydrophobicContact CG-CD1 4.3Å; L611-L643 HydrophobicContact CG-CD2 4.3Å; L611-I684 HydrophobicContact CD1-CD1 3.93Å
612L93.5Very high93Very high23 Ų2335.8 Ų35.812%0.1219%0.193CC..Hα-helixtrans-69.5-23.9178-70.9167.6000113P556 L590 M608 I610 Y614 N615P556-L612 HydrophobicContact CB-CD1 3.68Å; P556-L612 HydrophobicContact CG-CD1 4.06Å; L590-L612 HydrophobicContact CD2-CD2 4.1Å; L590-L612 HydrophobicContact CD2-CG 4.4Å; M608-L612 HydrophobicContact CB-CD1 4.43Å; M608-L612 WeakPolarHBondContact O-CB 3.46Å; M608-L612 WeakPolarHBondContact O-CG 3.29Å; M608-L612 PolarHBondContact O-N 2.76Å; I610-L612 VanDerWaalsContact C-N 3.29Å; I610-L612 PolarHBondContact O-N 2.98Å; L612-Y614 PolarHBondContact O-N 3.46Å; L612-N615 WeakPolarHBondContact CD2-ND2 3.34Å; L612-N615 WeakPolarHBondContact O-CB 3.3Å; L612-N615 PolarHBondContact O-N 3.35Å; L612-N615 PolarHBondContact O-ND2 3.39Å
613Q93.1Very high92.9Very high48 Ų4836.7 Ų36.722%0.22420%0.197CC..Hα-helixtrans-59.6-36.5173.3-60.1-52.9-53.700111.1A609 I610 L611 N615 T616 Y620 L625A609-Q613 WeakPolarHBondContact O-CG 3.37Å; A609-Q613 PolarHBondContact O-NE2 3.04Å; I610-Q613 WeakPolarHBondContact O-CB 3.41Å; I610-Q613 PolarHBondContact O-N 2.98Å; L611-Q613 VanDerWaalsContact C-N 3.3Å; L611-Q613 PolarHBondContact O-N 2.89Å; Q613-N615 PolarHBondContact O-N 3.39Å; Q613-T616 PolarHBondContact O-N 3.14Å; Q613-Y620 HydrophobicContact CB-CD2 4.26Å; Q613-Y620 HydrophobicContact CB-CE2 3.78Å; Q613-Y620 PolarHBondContact O-OH 3.21Å; Q613-L625 HydrophobicContact CB-CD2 4.3Å; Q613-L625 HydrophobicContact CG-CD2 4.12Å
614Y93.8Very high92.9Very high11 Ų1141 Ų414%0.04322%0.217CC..THydrogen-bonded Turntrans-71.11.4-178.8-65.4-89000114.8I610 L611 L612 E617 D618 Y620 L649 I669 L671I610-Y614 HydrophobicContact CG2-CE2 4.19Å; I610-Y614 WeakPolarHBondContact O-CD2 2.89Å; L611-Y614 PolarHBondContact O-N 3.01Å; L612-Y614 PolarHBondContact O-N 3.46Å; Y614-E617 VanDerWaalsContact CA-O 3.27Å; Y614-E617 WeakPolarHBondContact CA-O 3.23Å; Y614-E617 WeakPolarHBondContact CD1-O 3.43Å; Y614-D618 WeakPolarHBondContact CE1-O 3.33Å; Y614-Y620 HydrophobicContact CD1-CD2 4.05Å; Y614-Y620 HydrophobicContact CD1-CE2 4.23Å; Y614-Y620 AromaticContact CE1-CD2 3.82Å; Y614-Y620 HydrophobicContact CE1-CD2 3.82Å; Y614-Y620 HydrophobicContact CE1-CE2 4.46Å; Y614-Y620 HydrophobicContact CE2-CD2 4.34Å; Y614-Y620 HydrophobicContact CG-CD2 4.45Å; Y614-Y620 HydrophobicContact CG-CE2 4.41Å; Y614-Y620 AromaticContact CZ-CD2 3.97Å; Y614-L649 HydrophobicContact CD2-CD2 4.14Å; Y614-L649 HydrophobicContact CE1-CD2 4.16Å; Y614-L649 HydrophobicContact CE2-CD1 4.23Å; Y614-L649 HydrophobicContact CE2-CD2 3.64Å; Y614-I669 WeakPolarHBondContact OH-CG2 3.4Å; Y614-I669 PolarHBondContact OH-O 3.01Å; Y614-L671 HydrophobicContact CD1-CB 3.78Å; Y614-L671 HydrophobicContact CE1-CB 4.29Å; Y614-L671 HydrophobicContact CG-CB 4.37Å
615N92.3Very high92.9Very high119 Ų11940.5 Ų40.564%0.63621%0.213SC*.THydrogen-bonded Turntrans-74.1-17.5166.1-68.2-31.3000112.3L612 Q613L612-N615 WeakPolarHBondContact CD2-ND2 3.34Å; L612-N615 WeakPolarHBondContact O-CB 3.3Å; L612-N615 PolarHBondContact O-N 3.35Å; L612-N615 PolarHBondContact O-ND2 3.39Å; Q613-N615 PolarHBondContact O-N 3.39Å
616T91.8Very high92.9Very high116 Ų11641.1 Ų41.171%0.71222%0.217SC*.THydrogen-bonded Turntrans-103.1-48.3-178.2-49.20000112.1Q613Q613-T616 PolarHBondContact O-N 3.14Å
617E92Very high92.9Very high104 Ų10445 Ų4549%0.48624%0.238SC..  trans-135.4150.6176.7-54.7-175.9-179.500111.8Y614 S619 Y620Y614-E617 VanDerWaalsContact CA-O 3.27Å; Y614-E617 WeakPolarHBondContact CA-O 3.23Å; Y614-E617 WeakPolarHBondContact CD1-O 3.43Å; E617-S619 VanDerWaalsContact C-N 3.32Å; E617-S619 PolarHBondContact O-N 3.17Å; E617-Y620 HydrophobicContact CB-CE1 4.26Å; E617-Y620 HydrophobicContact CB-CE2 4.06Å; E617-Y620 WeakPolarHBondContact CB-OH 3.4Å; E617-Y620 PolarHBondContact N-OH 3.25Å; E617-Y620 VanDerWaalsContact O-CE2 3.26Å; E617-Y620 WeakPolarHBondContact O-CE2 3.34Å
618D90.6Very high92.8Very high99 Ų9946.9 Ų46.953%0.52925%0.252SS..SBendtrans-83-5.2-177.1-72.2-30000114.1Y614 K670 L671Y614-D618 WeakPolarHBondContact CE1-O 3.33Å; D618-K670 CarbonylContact O-C 3.49Å; D618-K670 WeakPolarHBondContact O-CA 3.47Å; D618-L671 PolarHBondContact O-N 3.31Å
619S93.1Very high92.7Very high51 Ų5146.4 Ų46.436%0.35725%0.249SC..EExtended strand (participates in β ladder)trans-147.7132.9-174.763.70000112.9E617 I669E617-S619 VanDerWaalsContact C-N 3.32Å; E617-S619 PolarHBondContact O-N 3.17Å; S619-I669 WeakPolarHBondContact CA-O 3.46Å
620Y94.4Very high92.6Very high22 Ų2250.8 Ų50.89%0.08627%0.27CS..EExtended strand (participates in β ladder)trans-137.9150.1177-68.8-78.7000111.6Q613 Y614 E617 Q624 L625 I669Q613-Y620 HydrophobicContact CB-CD2 4.26Å; Q613-Y620 HydrophobicContact CB-CE2 3.78Å; Q613-Y620 PolarHBondContact O-OH 3.21Å; Y614-Y620 HydrophobicContact CD1-CD2 4.05Å; Y614-Y620 HydrophobicContact CD1-CE2 4.23Å; Y614-Y620 AromaticContact CE1-CD2 3.82Å; Y614-Y620 HydrophobicContact CE1-CD2 3.82Å; Y614-Y620 HydrophobicContact CE1-CE2 4.46Å; Y614-Y620 HydrophobicContact CE2-CD2 4.34Å; Y614-Y620 HydrophobicContact CG-CD2 4.45Å; Y614-Y620 HydrophobicContact CG-CE2 4.41Å; Y614-Y620 AromaticContact CZ-CD2 3.97Å; E617-Y620 HydrophobicContact CB-CE1 4.26Å; E617-Y620 HydrophobicContact CB-CE2 4.06Å; E617-Y620 WeakPolarHBondContact CB-OH 3.4Å; E617-Y620 PolarHBondContact N-OH 3.25Å; E617-Y620 VanDerWaalsContact O-CE2 3.26Å; E617-Y620 WeakPolarHBondContact O-CE2 3.34Å; Y620-Q624 HydrophobicContact CD1-CB 4.28Å; Y620-L625 HydrophobicContact CD2-CD2 4.19Å; Y620-L625 HydrophobicContact CG-CD2 4Å; Y620-L625 HydrophobicContact CG-CG 4.49Å; Y620-I669 PolarHBondContact N-O 3.03Å; Y620-I669 PolarHBondContact O-N 3.06Å
621T93.4Very high92.4Very high31 Ų3150.9 Ų50.919%0.1927%0.27CS..EExtended strand (participates in β ladder)trans-78.3156.8166.768.70000111.2Q623 Q624 L625 T667 V668T621-Q623 PolarHBondContact O-N 2.7Å; T621-Q624 PolarHBondContact O-N 3.21Å; T621-Q624 VanDerWaalsContact O-N 3.14Å; T621-Q624 VanDerWaalsContact OG1-CG 3.27Å; T621-Q624 WeakPolarHBondContact OG1-CG 3.5Å; T621-Q624 PolarHBondContact OG1-N 3.31Å; T621-Q624 VanDerWaalsContact OG1-N 3.16Å; T621-Q624 PolarHBondContact OG1-OE1 2.94Å; T621-L625 PolarHBondContact O-N 3.4Å; T621-T667 CarbonylContact C-O 3.55Å; T621-T667 VanDerWaalsContact CA-O 3.3Å; T621-T667 WeakPolarHBondContact CA-O 3.44Å; T621-V668 HydrophobicContact CG2-CG2 4.16Å
622V91.9Very high92.1Very high3 Ų355.4 Ų55.42%0.01829%0.289CS..Hα-helixtrans-56.5-37.6173.8174.20000111.3L625 T626 L636 L640 F663 P665 T667 I669V622-L625 PolarHBondContact O-N 2.91Å; V622-T626 PolarHBondContact O-N 2.9Å; V622-T626 PolarHBondContact O-OG1 3.27Å; V622-L636 HydrophobicContact CG1-CD2 4.21Å; V622-L640 HydrophobicContact CG2-CD1 4.18Å; V622-F663 HydrophobicContact CG2-CB 4.41Å; V622-F663 HydrophobicContact CG2-CD1 4.08Å; V622-P665 PolarHBondContact N-O 3.09Å; V622-T667 PolarHBondContact N-O 3.39Å; V622-I669 HydrophobicContact CG2-CD1 3.88Å; V622-I669 HydrophobicContact CG2-CG1 4.37Å
623Q92.2Very high91.8Very high79 Ų7957.7 Ų57.737%0.36930%0.304SS..Hα-helixtrans-63.4-47175.5-173.258.342.200111.9T621 L625 T626 D627 P665T621-Q623 PolarHBondContact O-N 2.7Å; Q623-L625 VanDerWaalsContact C-N 3.31Å; Q623-L625 PolarHBondContact O-N 2.95Å; Q623-T626 WeakPolarHBondContact O-CB 3.34Å; Q623-T626 PolarHBondContact O-N 2.8Å; Q623-T626 VanDerWaalsContact O-N 3.08Å; Q623-D627 VanDerWaalsContact NE2-CG 3.27Å; Q623-D627 PolarHBondContact NE2-OD1 2.9Å; Q623-D627 PolarHBondContact NE2-OD2 2.89Å; Q623-D627 PolarHBondContact O-N 2.88Å; Q623-P665 HydrophobicContact CB-CB 4.07Å; Q623-P665 WeakPolarHBondContact CB-O 3.43Å; Q623-P665 PolarHBondContact N-O 3.14Å
624Q93Very high91.4Very high92 Ų9259.8 Ų59.843%0.4332%0.316SS..Hα-helixtrans-60.9-39.7177.5-73.8169.6-30.100112.2Y620 T621 T626 D627 S628Y620-Q624 HydrophobicContact CD1-CB 4.28Å; T621-Q624 PolarHBondContact O-N 3.21Å; T621-Q624 VanDerWaalsContact O-N 3.14Å; T621-Q624 VanDerWaalsContact OG1-CG 3.27Å; T621-Q624 WeakPolarHBondContact OG1-CG 3.5Å; T621-Q624 PolarHBondContact OG1-N 3.31Å; T621-Q624 VanDerWaalsContact OG1-N 3.16Å; T621-Q624 PolarHBondContact OG1-OE1 2.94Å; Q624-T626 VanDerWaalsContact C-N 3.35Å; Q624-D627 PolarHBondContact O-N 3.19Å; Q624-S628 WeakPolarHBondContact O-CB 3.07Å; Q624-S628 PolarHBondContact O-N 2.88Å; Q624-S628 PolarHBondContact O-OG 2.57Å
625L92.8Very high91Very high0 Ų061.2 Ų61.20%033%0.325CS..Hα-helixtrans-67.1-36174.7-67.6176.6000112I610 Q613 Y620 T621 V622 Q623 S628 T629 L636 L640I610-L625 HydrophobicContact CG2-CD1 4.33Å; I610-L625 HydrophobicContact CG2-CD2 4.38Å; Q613-L625 HydrophobicContact CB-CD2 4.3Å; Q613-L625 HydrophobicContact CG-CD2 4.12Å; Y620-L625 HydrophobicContact CD2-CD2 4.19Å; Y620-L625 HydrophobicContact CG-CD2 4Å; Y620-L625 HydrophobicContact CG-CG 4.49Å; T621-L625 PolarHBondContact O-N 3.4Å; V622-L625 PolarHBondContact O-N 2.91Å; Q623-L625 VanDerWaalsContact C-N 3.31Å; Q623-L625 PolarHBondContact O-N 2.95Å; L625-S628 WeakPolarHBondContact CA-OG 3.23Å; L625-S628 PolarHBondContact O-OG 2.99Å; L625-T629 WeakPolarHBondContact O-CB 3.33Å; L625-T629 WeakPolarHBondContact O-CG2 3.36Å; L625-T629 PolarHBondContact O-N 3.35Å; L625-T629 VanDerWaalsContact O-N 3.14Å; L625-T629 PolarHBondContact O-OG1 2.72Å; L625-L636 HydrophobicContact CB-CD1 4.49Å; L625-L636 HydrophobicContact CB-CD2 4.31Å; L625-L640 HydrophobicContact CD1-CD2 3.97Å
626T92.1Very high90.9Very high21 Ų2155.6 Ų55.613%0.12929%0.294CS..Hα-helixtrans-64-48.1174.4-55.70000110.7V622 Q623 Q624 Q630 L636V622-T626 PolarHBondContact O-N 2.9Å; V622-T626 PolarHBondContact O-OG1 3.27Å; Q623-T626 WeakPolarHBondContact O-CB 3.34Å; Q623-T626 PolarHBondContact O-N 2.8Å; Q623-T626 VanDerWaalsContact O-N 3.08Å; Q624-T626 VanDerWaalsContact C-N 3.35Å; T626-Q630 VanDerWaalsContact O-CA 3.23Å; T626-Q630 WeakPolarHBondContact O-CA 3.43Å; T626-Q630 PolarHBondContact O-N 3.07Å; T626-L636 WeakPolarHBondContact OG1-CD2 3.43Å
627D91.4Very high90.7Very high87 Ų8751.4 Ų51.447%0.46527%0.269SS..Hα-helixtrans-70.2-38.2-175.5-65.8-28.2000112.4Q623 Q624 Q630Q623-D627 VanDerWaalsContact NE2-CG 3.27Å; Q623-D627 PolarHBondContact NE2-OD1 2.9Å; Q623-D627 PolarHBondContact NE2-OD2 2.89Å; Q623-D627 PolarHBondContact O-N 2.88Å; Q624-D627 PolarHBondContact O-N 3.19Å; D627-Q630 PolarHBondContact O-NE2 2.8Å
628S91.1Very high90.5Very high44 Ų4447.9 Ų47.931%0.30825%0.252SS..Hα-helixtrans-71.9-41.7178.553.70000113A554 Q624 L625A554-S628 WeakPolarHBondContact CB-O 3.26Å; Q624-S628 WeakPolarHBondContact O-CB 3.07Å; Q624-S628 PolarHBondContact O-N 2.88Å; Q624-S628 PolarHBondContact O-OG 2.57Å; L625-S628 WeakPolarHBondContact CA-OG 3.23Å; L625-S628 PolarHBondContact O-OG 2.99Å
629T91.4Very high90.5Very high2 Ų243.2 Ų43.21%0.01223%0.227CC..Hα-helixtrans-91.9-17.9-175.966.90000113.5A554 A609 I610 L625 I631A554-T629 PolarHBondContact N-O 2.97Å; A609-T629 HydrophobicContact CB-CG2 4.12Å; I610-T629 HydrophobicContact CG1-CG2 4.33Å; L625-T629 WeakPolarHBondContact O-CB 3.33Å; L625-T629 WeakPolarHBondContact O-CG2 3.36Å; L625-T629 PolarHBondContact O-N 3.35Å; L625-T629 VanDerWaalsContact O-N 3.14Å; L625-T629 PolarHBondContact O-OG1 2.72Å; T629-I631 HydrophobicContact CG2-CD1 4.34Å; T629-I631 PolarHBondContact O-N 2.95Å; T629-I631 VanDerWaalsContact O-N 3.11Å; T629-I631 WeakPolarHBondContact OG1-CD1 3.32Å; T629-I631 WeakPolarHBondContact OG1-CG1 3.46Å; T629-I631 PolarHBondContact OG1-N 2.79Å
630Q92.1Very high90.4Very high94 Ų9440.8 Ų40.844%0.43921%0.21SC..  trans55.421-173.3-64.1-69.1-45.700113.8T552 A554 T626 D627T552-Q630 CarbonylContact C-O 3.53Å; T552-Q630 PolarHBondContact OG1-O 2.88Å; A554-Q630 HydrophobicContact CB-CB 4.31Å; A554-Q630 HydrophobicContact CB-CG 4.19Å; T626-Q630 VanDerWaalsContact O-CA 3.23Å; T626-Q630 WeakPolarHBondContact O-CA 3.43Å; T626-Q630 PolarHBondContact O-N 3.07Å; D627-Q630 PolarHBondContact O-NE2 2.8Å
631I89.4Confident90.1Very high1 Ų141.7 Ų41.71%0.00522%0.216CC..  trans-74.9137.1176.5-63.1168.8000109F553 F606 I610 T629 T633 I635 L636F553-I631 HydrophobicContact CD2-CD1 4.35Å; F553-I631 HydrophobicContact CD2-CG1 3.77Å; F553-I631 HydrophobicContact CE2-CD1 4.13Å; F553-I631 HydrophobicContact CE2-CG1 4.06Å; F606-I631 HydrophobicContact CB-CD1 3.97Å; F606-I631 HydrophobicContact CD1-CD1 4.08Å; F606-I631 HydrophobicContact CD1-CG1 4.22Å; F606-I631 HydrophobicContact CG-CD1 4.17Å; I610-I631 HydrophobicContact CG1-CD1 4.45Å; T629-I631 HydrophobicContact CG2-CD1 4.34Å; T629-I631 PolarHBondContact O-N 2.95Å; T629-I631 VanDerWaalsContact O-N 3.11Å; T629-I631 WeakPolarHBondContact OG1-CD1 3.32Å; T629-I631 WeakPolarHBondContact OG1-CG1 3.46Å; T629-I631 PolarHBondContact OG1-N 2.79Å; I631-T633 PolarHBondContact O-N 3.01Å; I631-I635 HydrophobicContact CG2-CB 3.93Å; I631-I635 HydrophobicContact CG2-CG2 3.91Å; I631-L636 HydrophobicContact CB-CB 4.46Å; I631-L636 HydrophobicContact CB-CD1 4.47Å; I631-L636 HydrophobicContact CD1-CD1 4.42Å; I631-L636 HydrophobicContact CG2-CB 4.03Å
632K88.1Confident89.9Confident117 Ų11741.7 Ų41.751%0.50921%0.214SC..  trans-57132.9174.3-165.4-170.5-172.8-150.50110.7D634 I635 L636K632-D634 VanDerWaalsContact C-N 3.29Å; K632-D634 VanDerWaalsContact CE-OD2 3.26Å; K632-D634 WeakPolarHBondContact CE-OD2 3.37Å; K632-D634 IonicContact NZ-OD2 2.7Å; K632-D634 PolarHBondContact NZ-OD2 2.96Å; K632-D634 PolarHBondContact O-N 3.41Å; K632-D634 VanDerWaalsContact O-N 3.14Å; K632-I635 HydrophobicContact CB-CD1 4.37Å; K632-I635 WeakPolarHBondContact O-CA 3.47Å; K632-I635 WeakPolarHBondContact O-CB 3.45Å; K632-I635 PolarHBondContact O-N 3.49Å; K632-L636 PolarHBondContact O-N 2.99Å
633T87Confident89.9Confident71 Ų7141.6 Ų41.644%0.43621%0.213SC..Hα-helixtrans-49.4-44.6-175.7-45.10000113.5I631 I635 L636 V637I631-T633 PolarHBondContact O-N 3.01Å; T633-I635 PolarHBondContact O-N 3.09Å; T633-L636 PolarHBondContact O-N 3.17Å; T633-V637 HydrophobicContact CG2-CG2 4.37Å; T633-V637 WeakPolarHBondContact O-CG2 3.38Å; T633-V637 PolarHBondContact O-N 3.34Å
634D84.9Confident89.8Confident91 Ų9138.3 Ų38.349%0.48720%0.198SC..Hα-helixtrans-57.6-35.3178.6-52.8-27.6000113.5K632 Q638K632-D634 VanDerWaalsContact C-N 3.29Å; K632-D634 VanDerWaalsContact CE-OD2 3.26Å; K632-D634 WeakPolarHBondContact CE-OD2 3.37Å; K632-D634 IonicContact NZ-OD2 2.7Å; K632-D634 PolarHBondContact NZ-OD2 2.96Å; K632-D634 PolarHBondContact O-N 3.41Å; K632-D634 VanDerWaalsContact O-N 3.14Å; D634-Q638 WeakPolarHBondContact O-CG 3.23Å; D634-Q638 PolarHBondContact O-NE2 3.38Å
635I86.1Confident89.6Confident42 Ų4238.9 Ų38.922%0.21520%0.199CC..Hα-helixtrans-81.7-44.5178.8-61.5174.6000109F606 I631 K632 T633 V637 Q638 V639 M688F606-I635 HydrophobicContact CD2-CG2 3.79Å; F606-I635 HydrophobicContact CE2-CG2 3.95Å; I631-I635 HydrophobicContact CG2-CB 3.93Å; I631-I635 HydrophobicContact CG2-CG2 3.91Å; K632-I635 HydrophobicContact CB-CD1 4.37Å; K632-I635 WeakPolarHBondContact O-CA 3.47Å; K632-I635 WeakPolarHBondContact O-CB 3.45Å; K632-I635 PolarHBondContact O-N 3.49Å; T633-I635 PolarHBondContact O-N 3.09Å; I635-V637 VanDerWaalsContact C-N 3.32Å; I635-V637 PolarHBondContact O-N 2.88Å; I635-Q638 PolarHBondContact O-N 3.39Å; I635-Q638 VanDerWaalsContact O-N 3.15Å; I635-V639 HydrophobicContact CG2-CG2 4.23Å; I635-V639 WeakPolarHBondContact O-CG2 3.42Å; I635-V639 PolarHBondContact O-N 2.88Å; I635-M688 HydrophobicContact CG2-CE 4.22Å; I635-M688 HydrophobicContact CG2-SD 4.4Å
636L89.3Confident89.3Confident0 Ų040.4 Ų40.40%021%0.21CC..Hα-helixtrans-55.1-48.5179.5-17770.7000111.1I610 V622 L625 T626 I631 K632 T633 Q638 V639 L640I610-L636 HydrophobicContact CD1-CD1 3.49Å; I610-L636 VanDerWaalsContact CD1-CD1 3.49Å; I610-L636 HydrophobicContact CG1-CD1 3.96Å; V622-L636 HydrophobicContact CG1-CD2 4.21Å; L625-L636 HydrophobicContact CB-CD1 4.49Å; L625-L636 HydrophobicContact CB-CD2 4.31Å; T626-L636 WeakPolarHBondContact OG1-CD2 3.43Å; I631-L636 HydrophobicContact CB-CB 4.46Å; I631-L636 HydrophobicContact CB-CD1 4.47Å; I631-L636 HydrophobicContact CD1-CD1 4.42Å; I631-L636 HydrophobicContact CG2-CB 4.03Å; K632-L636 PolarHBondContact O-N 2.99Å; T633-L636 PolarHBondContact O-N 3.17Å; L636-Q638 VanDerWaalsContact C-N 3.31Å; L636-Q638 PolarHBondContact O-N 3.01Å; L636-V639 PolarHBondContact O-N 3.05Å; L636-V639 VanDerWaalsContact O-N 3.14Å; L636-L640 HydrophobicContact CD1-CD1 4.49Å; L636-L640 HydrophobicContact CD2-CD1 4.41Å; L636-L640 HydrophobicContact CG-CD1 3.93Å; L636-L640 HydrophobicContact CG-CG 4.35Å; L636-L640 VanDerWaalsContact O-CG 3.28Å; L636-L640 WeakPolarHBondContact O-CG 3.43Å; L636-L640 PolarHBondContact O-N 3.48Å
637V89.1Confident89.2Confident29 Ų2946.1 Ų46.118%0.17623%0.233CC..Hα-helixtrans-56.1-44.8178.21670000111.7T633 I635 L640 Q641 F663T633-V637 HydrophobicContact CG2-CG2 4.37Å; T633-V637 WeakPolarHBondContact O-CG2 3.38Å; T633-V637 PolarHBondContact O-N 3.34Å; I635-V637 VanDerWaalsContact C-N 3.32Å; I635-V637 PolarHBondContact O-N 2.88Å; V637-L640 PolarHBondContact O-N 3.25Å; V637-Q641 VanDerWaalsContact O-CG 3.32Å; V637-Q641 WeakPolarHBondContact O-CG 3.3Å; V637-Q641 PolarHBondContact O-N 2.9Å; V637-F663 HydrophobicContact CB-CD2 4.41Å; V637-F663 HydrophobicContact CG1-CD2 3.49Å; V637-F663 VanDerWaalsContact CG1-CD2 3.49Å; V637-F663 HydrophobicContact CG1-CE2 4Å; V637-F663 HydrophobicContact CG1-CG 4.23Å; V637-F663 HydrophobicContact CG2-CB 3.88Å; V637-F663 HydrophobicContact CG2-CD2 4.33Å; V637-F663 HydrophobicContact CG2-CG 4.26Å
638Q87.3Confident89Confident29 Ų2942 Ų4214%0.13621%0.211CC..Hα-helixtrans-67.3-38.8178.7-71.1176.169.800112.3D634 I635 L636 L640 Q641 I642 M688D634-Q638 WeakPolarHBondContact O-CG 3.23Å; D634-Q638 PolarHBondContact O-NE2 3.38Å; I635-Q638 PolarHBondContact O-N 3.39Å; I635-Q638 VanDerWaalsContact O-N 3.15Å; L636-Q638 VanDerWaalsContact C-N 3.31Å; L636-Q638 PolarHBondContact O-N 3.01Å; Q638-L640 VanDerWaalsContact C-N 3.35Å; Q638-Q641 PolarHBondContact O-N 3.01Å; Q638-I642 WeakPolarHBondContact O-CG1 3.36Å; Q638-I642 PolarHBondContact O-N 3.48Å; Q638-I642 VanDerWaalsContact O-N 3.07Å; Q638-M688 HydrophobicContact CB-CG 4.14Å; Q638-M688 HydrophobicContact CB-SD 3.61Å
639V89.9Confident89Confident1 Ų140.1 Ų40.11%0.00620%0.197CC..Hα-helixtrans-63.7-43.6175179.90000110.2F606 Q607 I610 I635 L636 I642 L643 M688F606-V639 HydrophobicContact CB-CG2 4.18Å; Q607-V639 HydrophobicContact CB-CG1 4.32Å; Q607-V639 HydrophobicContact CG-CG1 3.53Å; I610-V639 HydrophobicContact CD1-CB 3.95Å; I610-V639 HydrophobicContact CD1-CG1 3.43Å; I610-V639 VanDerWaalsContact CD1-CG1 3.43Å; I635-V639 HydrophobicContact CG2-CG2 4.23Å; I635-V639 WeakPolarHBondContact O-CG2 3.42Å; I635-V639 PolarHBondContact O-N 2.88Å; L636-V639 PolarHBondContact O-N 3.05Å; L636-V639 VanDerWaalsContact O-N 3.14Å; V639-I642 PolarHBondContact O-N 3.39Å; V639-L643 HydrophobicContact CG1-CD1 4.18Å; V639-L643 HydrophobicContact CG1-CG 4.48Å; V639-L643 WeakPolarHBondContact O-CG 3.46Å; V639-L643 PolarHBondContact O-N 2.83Å; V639-M688 HydrophobicContact CG2-SD 4.31Å
640L91Very high89Confident0 Ų041.4 Ų41.40%021%0.205CC..Hα-helixtrans-62.3-44176.1-69.2171.4000111.9I610 V622 L625 L636 V637 Q638 I642 L643 L644 L649 F663 I669I610-L640 HydrophobicContact CD1-CD2 4.27Å; I610-L640 HydrophobicContact CG2-CD2 4.14Å; V622-L640 HydrophobicContact CG2-CD1 4.18Å; L625-L640 HydrophobicContact CD1-CD2 3.97Å; L636-L640 HydrophobicContact CD1-CD1 4.49Å; L636-L640 HydrophobicContact CD2-CD1 4.41Å; L636-L640 HydrophobicContact CG-CD1 3.93Å; L636-L640 HydrophobicContact CG-CG 4.35Å; L636-L640 VanDerWaalsContact O-CG 3.28Å; L636-L640 WeakPolarHBondContact O-CG 3.43Å; L636-L640 PolarHBondContact O-N 3.48Å; V637-L640 PolarHBondContact O-N 3.25Å; Q638-L640 VanDerWaalsContact C-N 3.35Å; L640-I642 VanDerWaalsContact C-N 3.3Å; L640-I642 PolarHBondContact O-N 2.98Å; L640-L643 PolarHBondContact O-N 3.11Å; L640-L643 VanDerWaalsContact O-N 3.13Å; L640-L644 WeakPolarHBondContact O-CB 3.28Å; L640-L644 VanDerWaalsContact O-CG 3.26Å; L640-L644 WeakPolarHBondContact O-CG 3.35Å; L640-L644 PolarHBondContact O-N 3.23Å; L640-L649 HydrophobicContact CD2-CD1 4.09Å; L640-F663 HydrophobicContact CB-CE1 4.37Å; L640-I669 HydrophobicContact CB-CD1 4.3Å; L640-I669 HydrophobicContact CD1-CD1 3.52Å; L640-I669 HydrophobicContact CD2-CD1 3.64Å; L640-I669 HydrophobicContact CG-CD1 4Å
641Q89.3Confident88.7Confident42 Ų4237.8 Ų37.820%0.19619%0.188CC..Hα-helixtrans-57.2-41.8174-75173.9-17.800112.1V637 Q638 K645 V658 F663V637-Q641 VanDerWaalsContact O-CG 3.32Å; V637-Q641 WeakPolarHBondContact O-CG 3.3Å; V637-Q641 PolarHBondContact O-N 2.9Å; Q638-Q641 PolarHBondContact O-N 3.01Å; Q641-K645 WeakPolarHBondContact O-CB 3.5Å; Q641-K645 VanDerWaalsContact O-CG 3.23Å; Q641-K645 WeakPolarHBondContact O-CG 3.35Å; Q641-K645 PolarHBondContact O-N 3Å; Q641-V658 HydrophobicContact CB-CG1 4.26Å; Q641-V658 HydrophobicContact CG-CG1 4.29Å; Q641-F663 HydrophobicContact CG-CE2 3.58Å; Q641-F663 HydrophobicContact CG-CZ 3.98Å
642I89.1Confident88Confident31 Ų3144.1 Ų44.116%0.15922%0.218CC..Hα-helixtrans-63.4-45.7175.5-66.9164.8000110.5Q638 V639 L640 K645 S646 M688Q638-I642 WeakPolarHBondContact O-CG1 3.36Å; Q638-I642 PolarHBondContact O-N 3.48Å; Q638-I642 VanDerWaalsContact O-N 3.07Å; V639-I642 PolarHBondContact O-N 3.39Å; L640-I642 VanDerWaalsContact C-N 3.3Å; L640-I642 PolarHBondContact O-N 2.98Å; I642-K645 PolarHBondContact O-N 2.78Å; I642-S646 WeakPolarHBondContact O-CB 3.24Å; I642-S646 PolarHBondContact O-N 3.44Å; I642-S646 PolarHBondContact O-OG 3.23Å; I642-M688 HydrophobicContact CD1-CG 3.98Å
643L91.4Very high87.4Confident0 Ų043.2 Ų43.20%022%0.219CC..Hα-helixtrans-66.4-39.5-179.2-66.5177.3000112.4Q607 I610 L611 V639 L640 S646 K647 L648 L649 I684Q607-L643 HydrophobicContact CG-CD2 4.42Å; I610-L643 HydrophobicContact CB-CD1 4.3Å; I610-L643 HydrophobicContact CD1-CD1 4.42Å; I610-L643 HydrophobicContact CG2-CD1 3.96Å; L611-L643 HydrophobicContact CD1-CD2 4.12Å; L611-L643 HydrophobicContact CD2-CD1 4.27Å; L611-L643 HydrophobicContact CD2-CD2 4.25Å; L611-L643 HydrophobicContact CG-CD1 4.3Å; L611-L643 HydrophobicContact CG-CD2 4.3Å; V639-L643 HydrophobicContact CG1-CD1 4.18Å; V639-L643 HydrophobicContact CG1-CG 4.48Å; V639-L643 WeakPolarHBondContact O-CG 3.46Å; V639-L643 PolarHBondContact O-N 2.83Å; L640-L643 PolarHBondContact O-N 3.11Å; L640-L643 VanDerWaalsContact O-N 3.13Å; L643-S646 WeakPolarHBondContact CA-OG 3.36Å; L643-S646 PolarHBondContact O-N 3.19Å; L643-S646 PolarHBondContact O-OG 2.74Å; L643-K647 PolarHBondContact O-N 2.93Å; L643-L648 HydrophobicContact CD2-CD1 4.1Å; L643-L648 PolarHBondContact O-N 2.93Å; L643-L648 VanDerWaalsContact O-N 3.09Å; L643-L649 HydrophobicContact CB-CD1 3.76Å; L643-L649 HydrophobicContact CB-CG 4.05Å; L643-L649 HydrophobicContact CD1-CD1 3.75Å; L643-L649 HydrophobicContact CG-CD1 4.4Å; L643-I684 HydrophobicContact CD2-CD1 3.91Å
644L90.1Very high86.3Confident11 Ų1147 Ų476%0.05823%0.232CC..Hα-helixtrans-65.5-46.9174.5-72.6166000111.8L640 S646 K647 L649 M651 V658 F663L640-L644 WeakPolarHBondContact O-CB 3.28Å; L640-L644 VanDerWaalsContact O-CG 3.26Å; L640-L644 WeakPolarHBondContact O-CG 3.35Å; L640-L644 PolarHBondContact O-N 3.23Å; L644-S646 PolarHBondContact O-N 2.8Å; L644-K647 WeakPolarHBondContact O-CA 3.49Å; L644-K647 PolarHBondContact O-N 2.95Å; L644-L649 HydrophobicContact CD2-CB 4.05Å; L644-L649 HydrophobicContact CG-CB 4.48Å; L644-M651 HydrophobicContact CD1-CE 4.16Å; L644-M651 HydrophobicContact CD1-CG 4.17Å; L644-M651 HydrophobicContact CD1-SD 3.97Å; L644-M651 HydrophobicContact CD2-CG 3.87Å; L644-V658 HydrophobicContact CB-CG1 3.71Å; L644-V658 HydrophobicContact CB-CG2 4.16Å; L644-V658 HydrophobicContact CD1-CG1 4.18Å; L644-F663 HydrophobicContact CD1-CE1 3.62Å; L644-F663 HydrophobicContact CD1-CZ 3.48Å; L644-F663 VanDerWaalsContact CD1-CZ 3.48Å
645K88.3Confident85.1Confident103 Ų10350.2 Ų50.245%0.44825%0.249SC..Hα-helixtrans-61.7-34.7174.7-74.4178.5-170-170.10112.6Q641 I642 K647 V658 D659Q641-K645 WeakPolarHBondContact O-CB 3.5Å; Q641-K645 VanDerWaalsContact O-CG 3.23Å; Q641-K645 WeakPolarHBondContact O-CG 3.35Å; Q641-K645 PolarHBondContact O-N 3Å; I642-K645 PolarHBondContact O-N 2.78Å; K645-K647 PolarHBondContact O-N 3.18Å; K645-V658 HydrophobicContact CG-CB 4.2Å; K645-V658 HydrophobicContact CG-CG1 3.89Å; K645-D659 WeakPolarHBondContact CE-OD1 3.5Å; K645-D659 VanDerWaalsContact CE-OD2 3.29Å; K645-D659 WeakPolarHBondContact CE-OD2 3.48Å; K645-D659 IonicContact NZ-OD1 2.97Å; K645-D659 PolarHBondContact NZ-OD1 2.93Å; K645-D659 IonicContact NZ-OD2 2.77Å; K645-D659 PolarHBondContact NZ-OD2 3.02Å
646S87.7Confident84.2Confident32 Ų3249.6 Ų49.622%0.22425%0.25CS..THydrogen-bonded Turntrans-71.8-8.2174.477.90000112.9I642 L643 L644 L648 Y675I642-S646 WeakPolarHBondContact O-CB 3.24Å; I642-S646 PolarHBondContact O-N 3.44Å; I642-S646 PolarHBondContact O-OG 3.23Å; L643-S646 WeakPolarHBondContact CA-OG 3.36Å; L643-S646 PolarHBondContact O-N 3.19Å; L643-S646 PolarHBondContact O-OG 2.74Å; L644-S646 PolarHBondContact O-N 2.8Å; S646-L648 PolarHBondContact O-N 3.37Å; S646-L648 WeakPolarHBondContact OG-CD1 3.27Å; S646-L648 WeakPolarHBondContact OG-CG 3.41Å; S646-Y675 VanDerWaalsContact O-CE2 3.25Å; S646-Y675 WeakPolarHBondContact O-CE2 3.4Å
647K88.4Confident83.3Confident141 Ų14153.5 Ų53.561%0.61327%0.271SS*.THydrogen-bonded Turntrans57.629.8-173.3-58.6-167.4173.9-164.30113.8L643 L644 K645 F672 Y675L643-K647 PolarHBondContact O-N 2.93Å; L644-K647 WeakPolarHBondContact O-CA 3.49Å; L644-K647 PolarHBondContact O-N 2.95Å; K645-K647 PolarHBondContact O-N 3.18Å; K647-F672 HydrophobicContact CB-CD1 4.41Å; K647-F672 WeakPolarHBondContact O-CD1 3.42Å; K647-Y675 WeakPolarHBondContact O-CD2 3.26Å
648L88.4Confident82.5Confident2 Ų253.4 Ų53.41%0.0127%0.27CS..SBendtrans-82.5-32.3168.8-71.7172.1000111F595 L601 L643 S646 F672 Y675 I684F595-L648 HydrophobicContact CE2-CD2 3.88Å; F595-L648 HydrophobicContact CZ-CD2 4.04Å; L601-L648 HydrophobicContact CD1-CD1 3.77Å; L601-L648 HydrophobicContact CD1-CD2 4.02Å; L601-L648 HydrophobicContact CD2-CD1 4.4Å; L601-L648 HydrophobicContact CD2-CD2 4.42Å; L643-L648 HydrophobicContact CD2-CD1 4.1Å; L643-L648 PolarHBondContact O-N 2.93Å; L643-L648 VanDerWaalsContact O-N 3.09Å; S646-L648 PolarHBondContact O-N 3.37Å; S646-L648 WeakPolarHBondContact OG-CD1 3.27Å; S646-L648 WeakPolarHBondContact OG-CG 3.41Å; L648-F672 PolarHBondContact O-N 3.18Å; L648-Y675 HydrophobicContact CD2-CD1 4.16Å; L648-Y675 HydrophobicContact CD2-CD2 3.87Å; L648-Y675 HydrophobicContact CD2-CE1 4.13Å; L648-Y675 HydrophobicContact CD2-CE2 3.82Å; L648-Y675 HydrophobicContact CD2-CG 4.02Å; L648-Y675 HydrophobicContact CG-CD2 4.44Å; L648-Y675 HydrophobicContact CG-CE2 4.19Å; L648-I684 HydrophobicContact CD1-CD1 3.8Å; L648-I684 HydrophobicContact CD1-CG2 4.08Å
649L91.2Very high81.6Confident3 Ų356.8 Ų56.82%0.01629%0.29CS..EExtended strand (participates in β ladder)trans-118.5160.9174-58.8179.6000109.6I610 Y614 L640 L643 L644 I669 K670 L671I610-L649 HydrophobicContact CG2-CD1 4.35Å; Y614-L649 HydrophobicContact CD2-CD2 4.14Å; Y614-L649 HydrophobicContact CE1-CD2 4.16Å; Y614-L649 HydrophobicContact CE2-CD1 4.23Å; Y614-L649 HydrophobicContact CE2-CD2 3.64Å; L640-L649 HydrophobicContact CD2-CD1 4.09Å; L643-L649 HydrophobicContact CB-CD1 3.76Å; L643-L649 HydrophobicContact CB-CG 4.05Å; L643-L649 HydrophobicContact CD1-CD1 3.75Å; L643-L649 HydrophobicContact CG-CD1 4.4Å; L644-L649 HydrophobicContact CD2-CB 4.05Å; L644-L649 HydrophobicContact CG-CB 4.48Å; L649-I669 HydrophobicContact CB-CG2 3.77Å; L649-I669 HydrophobicContact CD1-CG2 3.81Å; L649-I669 HydrophobicContact CG-CG2 4.24Å; L649-K670 CarbonylContact C-O 3.52Å; L649-K670 VanDerWaalsContact CA-O 3.31Å; L649-K670 WeakPolarHBondContact CA-O 3.23Å; L649-L671 HydrophobicContact CD2-CD1 4.26Å
650V89.8Confident80.4Confident30 Ų3064.3 Ų64.318%0.18232%0.324CS..EExtended strand (participates in β ladder)trans-140.5150.7177.366.80000110.3E654 K670 F672V650-E654 HydrophobicContact CG2-CG 3.97Å; V650-K670 HydrophobicContact CG1-CB 4.05Å; V650-K670 PolarHBondContact N-O 3.03Å; V650-K670 PolarHBondContact O-N 3.21Å; V650-F672 HydrophobicContact CB-CB 4.29Å; V650-F672 HydrophobicContact CB-CD2 4.37Å; V650-F672 HydrophobicContact CG1-CB 4.26Å; V650-F672 HydrophobicContact CG1-CD2 4.33Å
651M85.8Confident79.5Confident17 Ų1765.9 Ų65.98%0.08433%0.334CS..EExtended strand (participates in β ladder)trans-98.5165.1171.5-67.9179.8-61.900109.7L644 D653 A656 V661 F663 T667L644-M651 HydrophobicContact CD1-CE 4.16Å; L644-M651 HydrophobicContact CD1-CG 4.17Å; L644-M651 HydrophobicContact CD1-SD 3.97Å; L644-M651 HydrophobicContact CD2-CG 3.87Å; M651-D653 PolarHBondContact O-N 2.9Å; M651-A656 HydrophobicContact CE-CB 4.17Å; M651-V661 HydrophobicContact CE-CB 4.37Å; M651-V661 HydrophobicContact CE-CG1 4.23Å; M651-V661 HydrophobicContact CE-CG2 3.74Å; M651-V661 HydrophobicContact SD-CG1 3.97Å; M651-F663 HydrophobicContact SD-CE1 3.9Å; M651-F663 HydrophobicContact SD-CZ 4.33Å; M651-T667 HydrophobicContact SD-CG2 4.37Å
652E76.5Confident78.9Confident134 Ų13470.2 Ų70.263%0.62636%0.359SS*.SBendtrans-61.9-30.3176.8-63-163.3143.300113.2V668 K670E652-V668 HydrophobicContact CG-CB 4.48Å; E652-K670 WeakPolarHBondContact OE1-CE 3.49Å; E652-K670 IonicContact OE1-NZ 3.4Å; E652-K670 PolarHBondContact OE1-NZ 3.19Å
653D74.4Confident78.5Confident99 Ų9969.5 Ų69.553%0.52936%0.355SS..  trans-92.396.9169.5-171.7-5.8000110.5M651 N655 A656M651-D653 PolarHBondContact O-N 2.9Å; D653-N655 PolarHBondContact O-N 2.73Å; D653-N655 PolarHBondContact OD1-N 2.97Å; D653-N655 VanDerWaalsContact OD1-N 3.08Å; D653-A656 HydrophobicContact CB-CB 4.18Å; D653-A656 PolarHBondContact O-N 3.23Å; D653-A656 PolarHBondContact OD1-N 3.48Å
654E63.4Low78.2Confident151 Ų15175.4 Ų75.471%0.70638%0.38SS*.THydrogen-bonded Turntrans-68.4-16179.4-63.9-165.915600113.7V650V650-E654 HydrophobicContact CG2-CG 3.97Å
655N61.3Low78Confident157 Ų15778.4 Ų78.484%0.8440%0.4SS*.THydrogen-bonded Turntrans-95.8-4.4-178.6-70.4-31.9000113.3D653 N657D653-N655 PolarHBondContact O-N 2.73Å; D653-N655 PolarHBondContact OD1-N 2.97Å; D653-N655 VanDerWaalsContact OD1-N 3.08Å; N655-N657 PolarHBondContact O-N 3Å
656A65.8Low78Confident30 Ų3079 Ų7925%0.24841%0.408CS..SBendtrans-67.3131.7-179.600000111.7M651 D653 V658 V661M651-A656 HydrophobicContact CE-CB 4.17Å; D653-A656 HydrophobicContact CB-CB 4.18Å; D653-A656 PolarHBondContact O-N 3.23Å; D653-A656 PolarHBondContact OD1-N 3.48Å; A656-V658 PolarHBondContact O-N 2.88Å; A656-V658 VanDerWaalsContact O-N 3.08Å; A656-V661 HydrophobicContact CB-CG2 3.83Å
657N71.9Confident78Confident81 Ų8178.9 Ų78.943%0.43341%0.407SS..  trans-69.6105174.2-177.55.3000110N655 D659 E660 V661N655-N657 PolarHBondContact O-N 3Å; N657-D659 PolarHBondContact O-N 3.23Å; N657-D659 PolarHBondContact OD1-N 3.42Å; N657-E660 HydrophobicContact CB-CB 4.41Å; N657-E660 PolarHBondContact ND2-OE2 3.18Å; N657-E660 PolarHBondContact O-N 3.42Å; N657-V661 VanDerWaalsContact O-CG2 3.23Å; N657-V661 WeakPolarHBondContact O-CG2 3.35Å; N657-V661 PolarHBondContact O-N 3.37Å
658V71.8Confident78.1Confident27 Ų2774 Ų7416%0.16439%0.389CS..THydrogen-bonded Turntrans-53.9-26.4-176.2-176.50000113.5Q641 L644 K645 A656 E660Q641-V658 HydrophobicContact CB-CG1 4.26Å; Q641-V658 HydrophobicContact CG-CG1 4.29Å; L644-V658 HydrophobicContact CB-CG1 3.71Å; L644-V658 HydrophobicContact CB-CG2 4.16Å; L644-V658 HydrophobicContact CD1-CG1 4.18Å; K645-V658 HydrophobicContact CG-CB 4.2Å; K645-V658 HydrophobicContact CG-CG1 3.89Å; A656-V658 PolarHBondContact O-N 2.88Å; A656-V658 VanDerWaalsContact O-N 3.08Å; V658-E660 VanDerWaalsContact C-N 3.35Å
659D67.6Low78.3Confident101 Ų10174 Ų7454%0.5439%0.388SS..THydrogen-bonded Turntrans-75.9-18.4177.4-86.5-57.9000114.3K645 N657K645-D659 WeakPolarHBondContact CE-OD1 3.5Å; K645-D659 VanDerWaalsContact CE-OD2 3.29Å; K645-D659 WeakPolarHBondContact CE-OD2 3.48Å; K645-D659 IonicContact NZ-OD1 2.97Å; K645-D659 PolarHBondContact NZ-OD1 2.93Å; K645-D659 IonicContact NZ-OD2 2.77Å; K645-D659 PolarHBondContact NZ-OD2 3.02Å; N657-D659 PolarHBondContact O-N 3.23Å; N657-D659 PolarHBondContact OD1-N 3.42Å
660E66.1Low78.4Confident158 Ų15877.4 Ų77.474%0.73840%0.403SS*.THydrogen-bonded Turntrans-117.5-0.5-175-67.6174.1163.900112.9N657 V658 D662N657-E660 HydrophobicContact CB-CB 4.41Å; N657-E660 PolarHBondContact ND2-OE2 3.18Å; N657-E660 PolarHBondContact O-N 3.42Å; V658-E660 VanDerWaalsContact C-N 3.35Å; E660-D662 PolarHBondContact O-N 3.08Å
661V71.9Confident78.4Confident34 Ų3477.1 Ų77.121%0.20640%0.4CS..  trans-72.1121.8178.5179.60000110.8M651 A656 N657 F663M651-V661 HydrophobicContact CE-CB 4.37Å; M651-V661 HydrophobicContact CE-CG1 4.23Å; M651-V661 HydrophobicContact CE-CG2 3.74Å; M651-V661 HydrophobicContact SD-CG1 3.97Å; A656-V661 HydrophobicContact CB-CG2 3.83Å; N657-V661 VanDerWaalsContact O-CG2 3.23Å; N657-V661 WeakPolarHBondContact O-CG2 3.35Å; N657-V661 PolarHBondContact O-N 3.37Å; V661-F663 HydrophobicContact CB-CE2 4.24Å; V661-F663 HydrophobicContact CB-CZ 4.48Å; V661-F663 HydrophobicContact CG1-CD2 4.39Å; V661-F663 HydrophobicContact CG1-CE2 4.28Å; V661-F663 HydrophobicContact CG1-CZ 4.35Å; V661-F663 WeakPolarHBondContact O-CD2 3.49Å
662D76.5Confident78.7Confident133 Ų13379.2 Ų79.271%0.71141%0.409SS*.  trans-82.5110166.3-171.423.8000109.5E660 K664E660-D662 PolarHBondContact O-N 3.08Å; D662-K664 PolarHBondContact O-N 3.36Å; D662-K664 VanDerWaalsContact O-N 3.11Å
663F80.9Confident79.2Confident16 Ų1677.6 Ų77.67%0.0740%0.404CS..  trans-78.497.4-176.2-72.5-92.3000110.3V622 V637 L640 Q641 L644 M651 V661 I669V622-F663 HydrophobicContact CG2-CB 4.41Å; V622-F663 HydrophobicContact CG2-CD1 4.08Å; V637-F663 HydrophobicContact CB-CD2 4.41Å; V637-F663 HydrophobicContact CG1-CD2 3.49Å; V637-F663 VanDerWaalsContact CG1-CD2 3.49Å; V637-F663 HydrophobicContact CG1-CE2 4Å; V637-F663 HydrophobicContact CG1-CG 4.23Å; V637-F663 HydrophobicContact CG2-CB 3.88Å; V637-F663 HydrophobicContact CG2-CD2 4.33Å; V637-F663 HydrophobicContact CG2-CG 4.26Å; L640-F663 HydrophobicContact CB-CE1 4.37Å; Q641-F663 HydrophobicContact CG-CE2 3.58Å; Q641-F663 HydrophobicContact CG-CZ 3.98Å; L644-F663 HydrophobicContact CD1-CE1 3.62Å; L644-F663 HydrophobicContact CD1-CZ 3.48Å; L644-F663 VanDerWaalsContact CD1-CZ 3.48Å; M651-F663 HydrophobicContact SD-CE1 3.9Å; M651-F663 HydrophobicContact SD-CZ 4.33Å; V661-F663 HydrophobicContact CB-CE2 4.24Å; V661-F663 HydrophobicContact CB-CZ 4.48Å; V661-F663 HydrophobicContact CG1-CD2 4.39Å; V661-F663 HydrophobicContact CG1-CE2 4.28Å; V661-F663 HydrophobicContact CG1-CZ 4.35Å; V661-F663 WeakPolarHBondContact O-CD2 3.49Å; F663-I669 HydrophobicContact CD1-CD1 4.38Å; F663-I669 HydrophobicContact CE1-CD1 4.2Å
664K84.8Confident79.7Confident123 Ų12374.9 Ų74.954%0.53540%0.4SS..  trans-73.6152.4171.2-60.1-178.4-177175.60111.1D662 D666 T667D662-K664 PolarHBondContact O-N 3.36Å; D662-K664 VanDerWaalsContact O-N 3.11Å; K664-D666 WeakPolarHBondContact CB-OD1 3.25Å; K664-D666 PolarHBondContact O-N 3.14Å; K664-D666 VanDerWaalsContact O-N 3.14Å; K664-T667 PolarHBondContact N-OG1 3.48Å; K664-T667 VanDerWaalsContact N-OG1 3.09Å; K664-T667 VanDerWaalsContact O-CB 3.24Å; K664-T667 WeakPolarHBondContact O-CB 3.46Å; K664-T667 PolarHBondContact O-N 3.46Å; K664-T667 PolarHBondContact O-OG1 2.92Å
665P85.1Confident81Confident75 Ų7568.2 Ų68.249%0.48737%0.368SS..THydrogen-bonded Turntrans-56.2-30.3-179.3-26.235000114.8V622 Q623V622-P665 PolarHBondContact N-O 3.09Å; Q623-P665 HydrophobicContact CB-CB 4.07Å; Q623-P665 WeakPolarHBondContact CB-O 3.43Å; Q623-P665 PolarHBondContact N-O 3.14Å
666D87.9Confident82.2Confident114 Ų11469.2 Ų69.261%0.6137%0.365SS*.THydrogen-bonded Turntrans-85.4-5.2179.360.5-29.6000114.1K664 V668K664-D666 WeakPolarHBondContact CB-OD1 3.25Å; K664-D666 PolarHBondContact O-N 3.14Å; K664-D666 VanDerWaalsContact O-N 3.14Å; D666-V668 PolarHBondContact O-N 3.17Å
667T89.1Confident83.2Confident31 Ų3170.6 Ų70.619%0.1937%0.368CS..  trans-61.6122.1178.8-50.60000110.2T621 V622 M651 K664T621-T667 CarbonylContact C-O 3.55Å; T621-T667 VanDerWaalsContact CA-O 3.3Å; T621-T667 WeakPolarHBondContact CA-O 3.44Å; V622-T667 PolarHBondContact N-O 3.39Å; M651-T667 HydrophobicContact SD-CG2 4.37Å; K664-T667 PolarHBondContact N-OG1 3.48Å; K664-T667 VanDerWaalsContact N-OG1 3.09Å; K664-T667 VanDerWaalsContact O-CB 3.24Å; K664-T667 WeakPolarHBondContact O-CB 3.46Å; K664-T667 PolarHBondContact O-N 3.46Å; K664-T667 PolarHBondContact O-OG1 2.92Å
668V90.3Very high84.1Confident39 Ų3977 Ų7724%0.23639%0.392CS..EExtended strand (participates in β ladder)trans-86.7130.2178.7-178.10000110.3T621 E652 D666 K670T621-V668 HydrophobicContact CG2-CG2 4.16Å; E652-V668 HydrophobicContact CG-CB 4.48Å; D666-V668 PolarHBondContact O-N 3.17Å; V668-K670 HydrophobicContact CG1-CG 4.11Å
669I92.5Very high84.9Confident0 Ų082.7 Ų82.70%042%0.415CS..EExtended strand (participates in β ladder)trans-117.5129.5176.8-54.9-173.4000108.3Y614 S619 Y620 V622 L640 L649 F663Y614-I669 WeakPolarHBondContact OH-CG2 3.4Å; Y614-I669 PolarHBondContact OH-O 3.01Å; S619-I669 WeakPolarHBondContact CA-O 3.46Å; Y620-I669 PolarHBondContact N-O 3.03Å; Y620-I669 PolarHBondContact O-N 3.06Å; V622-I669 HydrophobicContact CG2-CD1 3.88Å; V622-I669 HydrophobicContact CG2-CG1 4.37Å; L640-I669 HydrophobicContact CB-CD1 4.3Å; L640-I669 HydrophobicContact CD1-CD1 3.52Å; L640-I669 HydrophobicContact CD2-CD1 3.64Å; L640-I669 HydrophobicContact CG-CD1 4Å; L649-I669 HydrophobicContact CB-CG2 3.77Å; L649-I669 HydrophobicContact CD1-CG2 3.81Å; L649-I669 HydrophobicContact CG-CG2 4.24Å; F663-I669 HydrophobicContact CD1-CD1 4.38Å; F663-I669 HydrophobicContact CE1-CD1 4.2Å
670K92.2Very high86Confident75 Ų7583.3 Ų83.333%0.32642%0.418SS..EExtended strand (participates in β ladder)trans-117.4150.6-175.1-57.8-174.8-178.5166.10111.2D618 L649 V650 E652 V668D618-K670 CarbonylContact O-C 3.49Å; D618-K670 WeakPolarHBondContact O-CA 3.47Å; L649-K670 CarbonylContact C-O 3.52Å; L649-K670 VanDerWaalsContact CA-O 3.31Å; L649-K670 WeakPolarHBondContact CA-O 3.23Å; V650-K670 HydrophobicContact CG1-CB 4.05Å; V650-K670 PolarHBondContact N-O 3.03Å; V650-K670 PolarHBondContact O-N 3.21Å; E652-K670 WeakPolarHBondContact OE1-CE 3.49Å; E652-K670 IonicContact OE1-NZ 3.4Å; E652-K670 PolarHBondContact OE1-NZ 3.19Å; V668-K670 HydrophobicContact CG1-CG 4.11Å
671L91.6Very high87.3Confident24 Ų2482.7 Ų82.713%0.12641%0.408CS..EExtended strand (participates in β ladder)trans-69.7129.2172.1-176.367000110.5C594 F595 Y614 D618 L649 L673C594-L671 HydrophobicContact CB-CD2 4.31Å; F595-L671 HydrophobicContact CZ-CD1 4.38Å; Y614-L671 HydrophobicContact CD1-CB 3.78Å; Y614-L671 HydrophobicContact CE1-CB 4.29Å; Y614-L671 HydrophobicContact CG-CB 4.37Å; D618-L671 PolarHBondContact O-N 3.31Å; L649-L671 HydrophobicContact CD2-CD1 4.26Å; L671-L673 HydrophobicContact CD2-CD2 3.96Å; L671-L673 HydrophobicContact CG-CD2 4.34Å; L671-L673 PolarHBondContact O-N 3.41Å
672F90.9Very high88.3Confident62 Ų6281.8 Ų81.827%0.27240%0.403SS..  trans-90.697.1179.2-178.1-110.4000112.2F595 K647 L648 V650 G674 Y675F595-F672 WeakPolarHBondContact CE1-O 3.44Å; K647-F672 HydrophobicContact CB-CD1 4.41Å; K647-F672 WeakPolarHBondContact O-CD1 3.42Å; L648-F672 PolarHBondContact O-N 3.18Å; V650-F672 HydrophobicContact CB-CB 4.29Å; V650-F672 HydrophobicContact CB-CD2 4.37Å; V650-F672 HydrophobicContact CG1-CB 4.26Å; V650-F672 HydrophobicContact CG1-CD2 4.33Å; F672-G674 VanDerWaalsContact CE1-CA 3.48Å; F672-G674 WeakPolarHBondContact CE1-O 3.4Å; F672-G674 PolarHBondContact O-N 2.89Å; F672-Y675 PolarHBondContact O-N 3.3Å
673L86.8Confident88.9Confident100 Ų10079.9 Ų79.952%0.52439%0.393SS..THydrogen-bonded Turntrans-67.1-16.6-178.8-61177.8000114.4C594 L671 Y675C594-L673 HydrophobicContact CB-CD2 4.45Å; L671-L673 HydrophobicContact CD2-CD2 3.96Å; L671-L673 HydrophobicContact CG-CD2 4.34Å; L671-L673 PolarHBondContact O-N 3.41Å; L673-Y675 PolarHBondContact O-N 3.34Å
674G85.9Confident89.4Confident42 Ų4279.3 Ų79.343%0.43339%0.391SS..THydrogen-bonded Turntrans-80.59.7-179.700000115.3F672 K676F672-G674 VanDerWaalsContact CE1-CA 3.48Å; F672-G674 WeakPolarHBondContact CE1-O 3.4Å; F672-G674 PolarHBondContact O-N 2.89Å; G674-K676 PolarHBondContact O-N 3.29Å
675Y89.3Confident89.6Confident10 Ų1075.6 Ų75.64%0.03938%0.376CS..  trans-57.6130.2-171.5-175.7-107000113.2F595 Y599 S646 K647 L648 F672 L673 N677F595-Y675 AromaticContact CD2-CD1 3.89Å; F595-Y675 HydrophobicContact CD2-CD1 3.89Å; F595-Y675 HydrophobicContact CD2-CG 4.34Å; F595-Y675 AromaticContact CE2-CD1 3.97Å; F595-Y675 HydrophobicContact CE2-CD1 3.97Å; F595-Y675 HydrophobicContact CE2-CG 4.17Å; F595-Y675 HydrophobicContact CG-CD1 4.45Å; F595-Y675 HydrophobicContact CZ-CG 4.37Å; Y599-Y675 HydrophobicContact CD1-CE1 4.28Å; Y599-Y675 AromaticContact CD2-CD1 3.71Å; Y599-Y675 HydrophobicContact CD2-CD1 3.71Å; Y599-Y675 AromaticContact CD2-CE1 3.84Å; Y599-Y675 HydrophobicContact CD2-CE1 3.84Å; Y599-Y675 HydrophobicContact CE1-CE1 4.47Å; Y599-Y675 AromaticContact CE2-CD1 3.7Å; Y599-Y675 HydrophobicContact CE2-CD1 3.7Å; Y599-Y675 HydrophobicContact CE2-CE1 4.01Å; Y599-Y675 HydrophobicContact CG-CD1 4.33Å; Y599-Y675 AromaticContact CG-CE1 3.99Å; Y599-Y675 HydrophobicContact CG-CE1 3.99Å; S646-Y675 VanDerWaalsContact O-CE2 3.25Å; S646-Y675 WeakPolarHBondContact O-CE2 3.4Å; K647-Y675 WeakPolarHBondContact O-CD2 3.26Å; L648-Y675 HydrophobicContact CD2-CD1 4.16Å; L648-Y675 HydrophobicContact CD2-CD2 3.87Å; L648-Y675 HydrophobicContact CD2-CE1 4.13Å; L648-Y675 HydrophobicContact CD2-CE2 3.82Å; L648-Y675 HydrophobicContact CD2-CG 4.02Å; L648-Y675 HydrophobicContact CG-CD2 4.44Å; L648-Y675 HydrophobicContact CG-CE2 4.19Å; F672-Y675 PolarHBondContact O-N 3.3Å; L673-Y675 PolarHBondContact O-N 3.34Å; Y675-N677 HydrophobicContact CE1-CB 4Å; Y675-N677 PolarHBondContact OH-ND2 3.37Å; Y675-N677 VanDerWaalsContact OH-ND2 3.1Å
676K86.9Confident89.5Confident178 Ų17875.8 Ų75.877%0.77438%0.376SS*.  trans-140.3127.7175.4-68.8-179.7-175172.50110.5G674G674-K676 PolarHBondContact O-N 3.29Å
677N88.2Confident88.9Confident59 Ų5974.4 Ų74.432%0.31637%0.373SS..  trans-131.7146.8172.7-159.4-46.8000110.8Y599 Y675 K679 V682Y599-N677 HydrophobicContact CD1-CB 4.38Å; Y599-N677 HydrophobicContact CE1-CB 3.86Å; Y599-N677 PolarHBondContact OH-N 3.3Å; Y599-N677 VanDerWaalsContact OH-N 3.15Å; Y599-N677 PolarHBondContact OH-O 3.39Å; Y675-N677 HydrophobicContact CE1-CB 4Å; Y675-N677 PolarHBondContact OH-ND2 3.37Å; Y675-N677 VanDerWaalsContact OH-ND2 3.1Å; N677-K679 VanDerWaalsContact C-N 3.27Å; N677-K679 PolarHBondContact O-N 2.94Å; N677-K679 PolarHBondContact OD1-N 2.89Å; N677-V682 HydrophobicContact CB-CG2 4.04Å; N677-V682 WeakPolarHBondContact ND2-CG2 3.21Å
678K89.3Confident88.3Confident215 Ų21574.2 Ų74.294%0.93537%0.371SS*.SBendtrans-66.3-29.7174.1-65.6-172.5179.7-178.40112
679K89.9Confident87.2Confident147 Ų14781 Ų8164%0.63940%0.397SS*.  trans-99135.9178.3-63.5-176.9179.3-178.90110Y599 N677 V682Y599-K679 WeakPolarHBondContact CD1-O 3.35Å; Y599-K679 WeakPolarHBondContact CE1-O 3.3Å; N677-K679 VanDerWaalsContact C-N 3.27Å; N677-K679 PolarHBondContact O-N 2.94Å; N677-K679 PolarHBondContact OD1-N 2.89Å; K679-V682 VanDerWaalsContact O-CG2 3.31Å; K679-V682 WeakPolarHBondContact O-CG2 3.36Å
680L90.8Very high86.1Confident115 Ų11585 Ų8560%0.60242%0.422SS*.SBendtrans-75-32.6173.8-66.4176.2000112.3Y599 T600Y599-L680 CarbonylContact C-O 3.42Å; Y599-L680 VanDerWaalsContact CA-O 3.29Å; Y599-L680 WeakPolarHBondContact CA-O 3.42Å; Y599-L680 HydrophobicContact CD1-CD2 4.37Å; Y599-L680 HydrophobicContact CE1-CD2 4.19Å; T600-L680 PolarHBondContact N-O 3.35Å
681R92.9Very high85Confident144 Ų14485 Ų8554%0.54342%0.423SS..EExtended strand (participates in β ladder)trans-103117.2171.4-166175.2-171.9-179.93.7109.2E589 T600 Q602E589-R681 IonicContact OE1-CZ 3.19Å; E589-R681 VanDerWaalsContact OE1-CZ 3.31Å; E589-R681 IonicContact OE1-NE 3.67Å; E589-R681 PolarHBondContact OE1-NE 3.47Å; E589-R681 IonicContact OE1-NH2 2.77Å; E589-R681 PolarHBondContact OE1-NH2 2.94Å; E589-R681 IonicContact OE2-NH2 3.65Å; E589-R681 PolarHBondContact OE2-NH2 3.39Å; T600-R681 HydrophobicContact CG2-CG 4.29Å; T600-R681 CarbonylContact O-C 3.35Å; T600-R681 WeakPolarHBondContact O-CA 3.46Å; Q602-R681 HydrophobicContact CG-CG 4.48Å
682V92.3Very high84Confident16 Ų1688.8 Ų88.810%0.09744%0.44CS..EExtended strand (participates in β ladder)trans-120.7126.2-172.7-174.90000108.8Y599 T600 L601 Q602 N677 K679 I684Y599-V682 HydrophobicContact CD1-CG2 4.45Å; T600-V682 PolarHBondContact O-N 3.1Å; L601-V682 CarbonylContact C-O 3.58Å; L601-V682 WeakPolarHBondContact CA-O 3.47Å; L601-V682 HydrophobicContact CD2-CB 4.05Å; Q602-V682 PolarHBondContact N-O 3.45Å; N677-V682 HydrophobicContact CB-CG2 4.04Å; N677-V682 WeakPolarHBondContact ND2-CG2 3.21Å; K679-V682 VanDerWaalsContact O-CG2 3.31Å; K679-V682 WeakPolarHBondContact O-CG2 3.36Å; V682-I684 HydrophobicContact CG1-CG2 4.05Å
683N90.1Very high83.1Confident92 Ų9292.5 Ų92.549%0.49246%0.456SS..EExtended strand (participates in β ladder)trans-90.3114.2172.7-17617.9000109.8Q602 N685Q602-N683 HydrophobicContact CB-CB 4.34Å; Q602-N683 PolarHBondContact O-OD1 2.94Å; N683-N685 WeakPolarHBondContact OD1-CB 3.18Å; N683-N685 PolarHBondContact OD1-N 3.42Å
684I91.4Very high82.6Confident5 Ų593.6 Ų93.63%0.02646%0.458CS..  trans-105.4-6.4175.761.6168.4000112.2L601 Q602 A603 Q607 L611 L643 L648 V682 V686L601-I684 HydrophobicContact CB-CD1 4.21Å; L601-I684 HydrophobicContact CB-CG1 4.47Å; L601-I684 HydrophobicContact CD1-CD1 4.33Å; Q602-I684 WeakPolarHBondContact O-CG1 3.44Å; Q602-I684 PolarHBondContact O-N 3.36Å; A603-I684 HydrophobicContact CB-CD1 3.89Å; A603-I684 HydrophobicContact CB-CG1 3.94Å; Q607-I684 PolarHBondContact NE2-O 2.95Å; Q607-I684 PolarHBondContact OE1-O 3.44Å; L611-I684 HydrophobicContact CD1-CD1 3.93Å; L643-I684 HydrophobicContact CD2-CD1 3.91Å; L648-I684 HydrophobicContact CD1-CD1 3.8Å; L648-I684 HydrophobicContact CD1-CG2 4.08Å; V682-I684 HydrophobicContact CG1-CG2 4.05Å; I684-V686 PolarHBondContact O-N 3.3Å
685N88.3Confident82.1Confident44 Ų4493.9 Ų93.924%0.23545%0.448CS..  trans-75.374.8173.7-171.35.5000110.6Q602 N683Q602-N685 PolarHBondContact O-N 3.3Å; Q602-N685 VanDerWaalsContact O-N 3.08Å; N683-N685 WeakPolarHBondContact OD1-CB 3.18Å; N683-N685 PolarHBondContact OD1-N 3.42Å
686V83.1Confident81.6Confident79 Ų7995.7 Ų95.748%0.47946%0.457SS..PPolyproline II helixtrans-95.7132.1176.8-176.80000108.6I684I684-V686 PolarHBondContact O-N 3.3Å
687P74.9Confident81.3Confident86 Ų8691.9 Ų91.956%0.55844%0.442SS*.PPolyproline II helixtrans-63.9139.5179.824.9-33.4000111.9
688M76.8Confident81.1Confident27 Ų2791.1 Ų91.113%0.13344%0.44CS..PPolyproline II helixtrans-76.1132.9-178.5-72.6-179.9-88.500111.5I635 Q638 V639 I642 E691 Q692I635-M688 HydrophobicContact CG2-CE 4.22Å; I635-M688 HydrophobicContact CG2-SD 4.4Å; Q638-M688 HydrophobicContact CB-CG 4.14Å; Q638-M688 HydrophobicContact CB-SD 3.61Å; V639-M688 HydrophobicContact CG2-SD 4.31Å; I642-M688 HydrophobicContact CD1-CG 3.98Å; M688-E691 HydrophobicContact CB-CB 3.89Å; M688-Q692 PolarHBondContact O-N 3.23Å
689K68.1Low80.9Confident180 Ų18081.2 Ų81.278%0.78340%0.397SS*.Hα-helixtrans-68.2-44.6-175.8-72.2-176.2-179.9177.90112.8E691 Q692K689-E691 VanDerWaalsContact C-N 3.32Å; K689-E691 PolarHBondContact O-N 2.77Å; K689-Q692 PolarHBondContact O-N 3.01Å
690T67.9Low80.6Confident86 Ų8676.6 Ų76.653%0.52838%0.378SS..Hα-helixtrans-66.1-38.2-178-47.30000111.2Q692 K693 Q694T690-Q692 VanDerWaalsContact C-N 3.35Å; T690-Q692 PolarHBondContact O-N 3.16Å; T690-K693 PolarHBondContact O-N 3.19Å; T690-Q694 PolarHBondContact O-N 3.42Å; T690-Q694 VanDerWaalsContact O-N 3.12Å
691E69Low80.4Confident75 Ų7577.3 Ų77.335%0.3538%0.376SS..Hα-helixtrans-57.3-46.1174.9-170.8-177.1-171.300111.2M688 K689 K693 Q694 E695M688-E691 HydrophobicContact CB-CB 3.89Å; K689-E691 VanDerWaalsContact C-N 3.32Å; K689-E691 PolarHBondContact O-N 2.77Å; E691-K693 VanDerWaalsContact C-N 3.32Å; E691-K693 PolarHBondContact O-N 3.11Å; E691-Q694 PolarHBondContact O-N 3.05Å; E691-E695 WeakPolarHBondContact O-CB 3.4Å; E691-E695 PolarHBondContact O-N 3.38Å
692Q70.8Confident80.1Confident103 Ų10372.1 Ų72.148%0.48136%0.359SS..Hα-helixtrans-59.6-39.5-179.6-69.8178.16.200113.5M688 K689 T690 Q696M688-Q692 PolarHBondContact O-N 3.23Å; K689-Q692 PolarHBondContact O-N 3.01Å; T690-Q692 VanDerWaalsContact C-N 3.35Å; T690-Q692 PolarHBondContact O-N 3.16Å; Q692-Q696 PolarHBondContact O-N 3.36Å; Q692-Q696 VanDerWaalsContact O-N 3.15Å
693K72.9Confident79.9Confident139 Ų13971.7 Ų71.760%0.60436%0.356SS*.Hα-helixtrans-70.3-48.2179.4-169.6179.9177.4-176.20111.2T690 E691 E695 Q696 E697T690-K693 PolarHBondContact O-N 3.19Å; E691-K693 VanDerWaalsContact C-N 3.32Å; E691-K693 PolarHBondContact O-N 3.11Å; K693-E695 VanDerWaalsContact C-N 3.27Å; K693-E695 PolarHBondContact O-N 2.94Å; K693-Q696 WeakPolarHBondContact O-CB 3.4Å; K693-Q696 PolarHBondContact O-N 3.3Å; K693-Q696 VanDerWaalsContact O-N 3.16Å; K693-E697 PolarHBondContact O-N 3.14Å; K693-E697 VanDerWaalsContact O-N 3.13Å
694Q75.8Confident79.8Confident123 Ų12373.1 Ų73.158%0.57536%0.36SS*.Hα-helixtrans-61.1-38177.5-172.3178.113.200112T690 E691 Q696 T698T690-Q694 PolarHBondContact O-N 3.42Å; T690-Q694 VanDerWaalsContact O-N 3.12Å; E691-Q694 PolarHBondContact O-N 3.05Å; Q694-Q696 VanDerWaalsContact C-N 3.34Å; Q694-T698 WeakPolarHBondContact O-CB 3.38Å; Q694-T698 PolarHBondContact O-N 3.16Å; Q694-T698 PolarHBondContact O-OG1 3.03Å
695E76Confident79.6Confident49 Ų4978.2 Ų78.223%0.22938%0.384CS..Hα-helixtrans-68.4-34.6178.9-150.9-158.5163.600111.5K468 K472 E691 K693 T699K468-E695 HydrophobicContact CD-CG 4.41Å; K468-E695 VanDerWaalsContact CD-OE1 3.23Å; K468-E695 WeakPolarHBondContact CD-OE1 3.43Å; K468-E695 WeakPolarHBondContact CE-OE1 3.33Å; K468-E695 PolarHBondContact NZ-O 2.82Å; K468-E695 IonicContact NZ-OE1 3.62Å; K468-E695 PolarHBondContact NZ-OE1 2.75Å; K468-E695 VanDerWaalsContact NZ-OE1 3.17Å; K468-E695 IonicContact NZ-OE2 2.97Å; K468-E695 PolarHBondContact NZ-OE2 3.25Å; K472-E695 WeakPolarHBondContact CE-OE1 3.32Å; K472-E695 IonicContact NZ-OE1 2.84Å; K472-E695 PolarHBondContact NZ-OE1 3.29Å; K472-E695 IonicContact NZ-OE2 3.69Å; K472-E695 PolarHBondContact NZ-OE2 3.03Å; E691-E695 WeakPolarHBondContact O-CB 3.4Å; E691-E695 PolarHBondContact O-N 3.38Å; K693-E695 VanDerWaalsContact C-N 3.27Å; K693-E695 PolarHBondContact O-N 2.94Å; E695-T699 WeakPolarHBondContact O-CB 3.35Å; E695-T699 PolarHBondContact O-N 3.36Å; E695-T699 PolarHBondContact O-OG1 3.43Å
696Q77.9Confident79.6Confident47 Ų4779.8 Ų79.822%0.2239%0.392CS..Hα-helixtrans-67.6-47.5175.9-178.3174.8-1.800111.4E420 F465 Q692 K693 Q694 T698 T699 H700E420-Q696 PolarHBondContact OE1-NE2 3.09Å; E420-Q696 PolarHBondContact OE2-NE2 2.98Å; F465-Q696 HydrophobicContact CE1-CG 4.2Å; F465-Q696 HydrophobicContact CZ-CG 4.29Å; Q692-Q696 PolarHBondContact O-N 3.36Å; Q692-Q696 VanDerWaalsContact O-N 3.15Å; K693-Q696 WeakPolarHBondContact O-CB 3.4Å; K693-Q696 PolarHBondContact O-N 3.3Å; K693-Q696 VanDerWaalsContact O-N 3.16Å; Q694-Q696 VanDerWaalsContact C-N 3.34Å; Q696-T698 PolarHBondContact O-N 3.14Å; Q696-T699 WeakPolarHBondContact O-CB 3.39Å; Q696-T699 PolarHBondContact O-N 2.95Å; Q696-T699 VanDerWaalsContact O-N 3.13Å; Q696-H700 PolarHBondContact O-CD2 2.79Å; Q696-H700 PolarHBondContact O-N 2.81Å; Q696-H700 VanDerWaalsContact O-N 3.1Å
697E80.4Confident80.1Confident99 Ų9977.7 Ų77.746%0.46338%0.376SS..Hα-helixtrans-61.6-43.6176.8-69.3175.2-167.800111.7K693 T699 H700 K701K693-E697 PolarHBondContact O-N 3.14Å; K693-E697 VanDerWaalsContact O-N 3.13Å; E697-T699 VanDerWaalsContact C-N 3.26Å; E697-T699 PolarHBondContact O-N 2.94Å; E697-H700 PolarHBondContact O-N 3.48Å; E697-K701 WeakPolarHBondContact O-CG 3.27Å; E697-K701 PolarHBondContact O-N 3.41Å
698T83.7Confident80.8Confident43 Ų4378.2 Ų78.226%0.26437%0.369SS..Hα-helixtrans-61.9-35.7175-54.60000111.7Q694 Q696 K701 N702Q694-T698 WeakPolarHBondContact O-CB 3.38Å; Q694-T698 PolarHBondContact O-N 3.16Å; Q694-T698 PolarHBondContact O-OG1 3.03Å; Q696-T698 PolarHBondContact O-N 3.14Å; T698-K701 PolarHBondContact O-N 3.14Å; T698-N702 WeakPolarHBondContact O-CB 3.03Å; T698-N702 PolarHBondContact O-N 3.18Å; T698-N702 PolarHBondContact O-ND2 3.01Å; T698-N702 VanDerWaalsContact O-ND2 3.14Å
699T85Confident81.5Confident6 Ų682 Ų824%0.03739%0.389CS..Hα-helixtrans-63.9-44.9176.4-55.90000110.9K464 F465 K468 E695 Q696 E697 N702 I703K464-T699 HydrophobicContact CB-CG2 4.45Å; K464-T699 HydrophobicContact CD-CG2 4.23Å; F465-T699 HydrophobicContact CD1-CG2 4.23Å; F465-T699 HydrophobicContact CD2-CG2 4.36Å; F465-T699 HydrophobicContact CE1-CG2 3.93Å; F465-T699 HydrophobicContact CE2-CG2 4.05Å; F465-T699 HydrophobicContact CG-CG2 4.43Å; F465-T699 HydrophobicContact CZ-CG2 3.81Å; K468-T699 PolarHBondContact NZ-OG1 2.93Å; E695-T699 WeakPolarHBondContact O-CB 3.35Å; E695-T699 PolarHBondContact O-N 3.36Å; E695-T699 PolarHBondContact O-OG1 3.43Å; Q696-T699 WeakPolarHBondContact O-CB 3.39Å; Q696-T699 PolarHBondContact O-N 2.95Å; Q696-T699 VanDerWaalsContact O-N 3.13Å; E697-T699 VanDerWaalsContact C-N 3.26Å; E697-T699 PolarHBondContact O-N 2.94Å; T699-N702 PolarHBondContact O-N 3.04Å; T699-I703 HydrophobicContact CG2-CD1 4.16Å; T699-I703 WeakPolarHBondContact O-CD1 3.45Å; T699-I703 VanDerWaalsContact O-CG1 3.29Å; T699-I703 WeakPolarHBondContact O-CG1 3.26Å; T699-I703 PolarHBondContact O-N 3.28Å; T699-I703 VanDerWaalsContact O-N 3.09Å
700H85Confident82.6Confident50 Ų5076.7 Ų76.723%0.23137%0.369CS..Hα-helixtrans-62.8-45.3176.7-79.3-66.9000112.3E420 F465 Q696 E697 N702 I703 E704E420-H700 IonicContact OE2-CE1 2.74Å; E420-H700 IonicContact OE2-NE2 3.29Å; E420-H700 PolarHBondContact OE2-NE2 3.03Å; F465-H700 AromaticContact CE2-CE1 3.64Å; F465-H700 AromaticContact CE2-NE2 3.77Å; F465-H700 AromaticContact CZ-CD2 3.83Å; F465-H700 AromaticContact CZ-CE1 3.8Å; F465-H700 AromaticContact CZ-NE2 3.43Å; F465-H700 WeakPolarHBondContact CZ-NE2 3.34Å; Q696-H700 PolarHBondContact O-CD2 2.79Å; Q696-H700 PolarHBondContact O-N 2.81Å; Q696-H700 VanDerWaalsContact O-N 3.1Å; E697-H700 PolarHBondContact O-N 3.48Å; H700-N702 PolarHBondContact O-N 3.2Å; H700-I703 WeakPolarHBondContact O-CB 3.06Å; H700-I703 PolarHBondContact O-N 3.02Å; H700-I703 VanDerWaalsContact O-N 3.17Å; H700-E704 PolarHBondContact O-N 2.64Å; H700-E704 VanDerWaalsContact O-N 3.14Å
701K86.1Confident83.9Confident130 Ų13072.7 Ų72.757%0.56534%0.344SS*.Hα-helixtrans-57.7-46.9175.7-71.4178.6-178.7176.60112.3E697 T698 I703 E704 E705E697-K701 WeakPolarHBondContact O-CG 3.27Å; E697-K701 PolarHBondContact O-N 3.41Å; T698-K701 PolarHBondContact O-N 3.14Å; K701-I703 VanDerWaalsContact C-N 3.3Å; K701-I703 PolarHBondContact O-N 3.38Å; K701-E704 PolarHBondContact O-N 2.7Å; K701-E705 PolarHBondContact O-N 3.27Å; K701-E705 VanDerWaalsContact O-N 3.08Å
702N86.8Confident85.1Confident36 Ų3670.1 Ų70.119%0.19333%0.332CS..Hα-helixtrans-60.4-39177.7-70.5-24000112.1T698 T699 H700 E705 D706T698-N702 WeakPolarHBondContact O-CB 3.03Å; T698-N702 PolarHBondContact O-N 3.18Å; T698-N702 PolarHBondContact O-ND2 3.01Å; T698-N702 VanDerWaalsContact O-ND2 3.14Å; T699-N702 PolarHBondContact O-N 3.04Å; H700-N702 PolarHBondContact O-N 3.2Å; N702-E705 PolarHBondContact O-N 3.46Å; N702-D706 WeakPolarHBondContact O-CB 3.41Å; N702-D706 VanDerWaalsContact O-CG 3.26Å; N702-D706 PolarHBondContact O-N 3.21Å
703I88.8Confident86.1Confident7 Ų767.5 Ų67.54%0.03633%0.328CS..Hα-helixtrans-62-44.5176.7-68.3159.3000110.6V461 K464 F465 T699 H700 K701 E705 D706 R707V461-I703 HydrophobicContact CB-CD1 4.43Å; V461-I703 HydrophobicContact CG1-CD1 4.28Å; V461-I703 HydrophobicContact CG2-CD1 4.34Å; V461-I703 HydrophobicContact CG2-CG2 4.13Å; K464-I703 HydrophobicContact CB-CD1 3.86Å; K464-I703 HydrophobicContact CB-CG1 3.79Å; K464-I703 HydrophobicContact CG-CD1 4.37Å; K464-I703 HydrophobicContact CG-CG1 3.77Å; F465-I703 HydrophobicContact CD2-CD1 4.44Å; F465-I703 HydrophobicContact CE2-CD1 4.09Å; T699-I703 HydrophobicContact CG2-CD1 4.16Å; T699-I703 WeakPolarHBondContact O-CD1 3.45Å; T699-I703 VanDerWaalsContact O-CG1 3.29Å; T699-I703 WeakPolarHBondContact O-CG1 3.26Å; T699-I703 PolarHBondContact O-N 3.28Å; T699-I703 VanDerWaalsContact O-N 3.09Å; H700-I703 WeakPolarHBondContact O-CB 3.06Å; H700-I703 PolarHBondContact O-N 3.02Å; H700-I703 VanDerWaalsContact O-N 3.17Å; K701-I703 VanDerWaalsContact C-N 3.3Å; K701-I703 PolarHBondContact O-N 3.38Å; I703-E705 VanDerWaalsContact C-N 3.34Å; I703-E705 PolarHBondContact O-N 3.23Å; I703-D706 PolarHBondContact O-N 2.76Å; I703-R707 HydrophobicContact CG2-CG 4.42Å; I703-R707 WeakPolarHBondContact O-CB 3.36Å; I703-R707 VanDerWaalsContact O-CG 3.25Å; I703-R707 WeakPolarHBondContact O-CG 3.48Å; I703-R707 PolarHBondContact O-N 3.14Å
704E86.6Confident87.1Confident122 Ų12261 Ų6157%0.5730%0.3SS*.Hα-helixtrans-64.6-37.8179-67.3-169.6165.900112.9H700 K701 K708H700-E704 PolarHBondContact O-N 2.64Å; H700-E704 VanDerWaalsContact O-N 3.14Å; K701-E704 PolarHBondContact O-N 2.7Å; E704-K708 WeakPolarHBondContact O-CG 3.39Å; E704-K708 PolarHBondContact O-N 2.98Å
705E88.1Confident88.1Confident112 Ų11255.1 Ų55.152%0.52327%0.273SS..Hα-helixtrans-66.8-46.7174.4-69.9-178.8176.700111.8K701 N702 I703 R707 K708 L709K701-E705 PolarHBondContact O-N 3.27Å; K701-E705 VanDerWaalsContact O-N 3.08Å; N702-E705 PolarHBondContact O-N 3.46Å; I703-E705 VanDerWaalsContact C-N 3.34Å; I703-E705 PolarHBondContact O-N 3.23Å; E705-R707 VanDerWaalsContact C-N 3.28Å; E705-R707 PolarHBondContact O-N 3.44Å; E705-K708 WeakPolarHBondContact O-CB 3.34Å; E705-K708 PolarHBondContact O-N 3.43Å; E705-K708 VanDerWaalsContact O-N 3.11Å; E705-L709 PolarHBondContact O-N 3.11Å; E705-L709 VanDerWaalsContact O-N 3.1Å
706D88.7Confident89Confident77 Ų7754.2 Ų54.241%0.41227%0.27SS..Hα-helixtrans-57.7-42176-76.5-17.7000111N702 I703 K708 L709 L710N702-D706 WeakPolarHBondContact O-CB 3.41Å; N702-D706 VanDerWaalsContact O-CG 3.26Å; N702-D706 PolarHBondContact O-N 3.21Å; I703-D706 PolarHBondContact O-N 2.76Å; D706-K708 PolarHBondContact O-N 2.92Å; D706-L709 PolarHBondContact O-N 2.9Å; D706-L710 WeakPolarHBondContact O-CB 3.46Å; D706-L710 VanDerWaalsContact O-CG 3.31Å; D706-L710 WeakPolarHBondContact O-CG 3.44Å; D706-L710 PolarHBondContact O-N 2.91Å
707R91.7Very high89.7Confident35 Ų3559.4 Ų59.413%0.13229%0.288CS..Hα-helixtrans-59.9-44.4175.3-75.6172.8174.4-159.1-12.8112.1D458 D460 I703 E705 L709 L710 I711 F742D458-R707 IonicContact OD1-CZ 3Å; D458-R707 IonicContact OD1-NH1 3.73Å; D458-R707 IonicContact OD1-NH2 2.91Å; D458-R707 PolarHBondContact OD1-NH2 3.31Å; D458-R707 IonicContact OD2-NH2 3.73Å; D460-R707 IonicContact OD1-CZ 2.77Å; D460-R707 IonicContact OD1-NE 3.83Å; D460-R707 IonicContact OD1-NH2 3.86Å; D460-R707 PolarHBondContact OD1-NH2 2.94Å; D460-R707 WeakPolarHBondContact OD2-CG 3.38Å; D460-R707 IonicContact OD2-CZ 2.68Å; D460-R707 IonicContact OD2-NE 3.76Å; D460-R707 PolarHBondContact OD2-NE 3.19Å; D460-R707 IonicContact OD2-NH2 2.81Å; D460-R707 PolarHBondContact OD2-NH2 3.44Å; I703-R707 HydrophobicContact CG2-CG 4.42Å; I703-R707 WeakPolarHBondContact O-CB 3.36Å; I703-R707 VanDerWaalsContact O-CG 3.25Å; I703-R707 WeakPolarHBondContact O-CG 3.48Å; I703-R707 PolarHBondContact O-N 3.14Å; E705-R707 VanDerWaalsContact C-N 3.28Å; E705-R707 PolarHBondContact O-N 3.44Å; R707-L709 VanDerWaalsContact C-N 3.34Å; R707-L709 PolarHBondContact O-N 3.27Å; R707-L710 PolarHBondContact O-N 3.36Å; R707-I711 WeakPolarHBondContact O-CB 3.38Å; R707-I711 WeakPolarHBondContact O-CD1 3.35Å; R707-I711 WeakPolarHBondContact O-CG1 3.46Å; R707-I711 PolarHBondContact O-N 3.39Å; R707-F742 HydrophobicContact CB-CE1 4.49Å; R707-F742 HydrophobicContact CB-CE2 4.12Å; R707-F742 HydrophobicContact CB-CZ 3.91Å; R707-F742 HydrophobicContact CG-CD1 4.25Å; R707-F742 HydrophobicContact CG-CD2 4.16Å; R707-F742 HydrophobicContact CG-CE1 3.95Å; R707-F742 HydrophobicContact CG-CE2 3.83Å; R707-F742 HydrophobicContact CG-CG 4.37Å; R707-F742 HydrophobicContact CG-CZ 3.72Å
708K91Very high90.4Very high97 Ų9755.1 Ų55.142%0.42227%0.268SS..Hα-helixtrans-60.9-43.6177.9-71.4170.1-172.21690111.4E704 E705 D706 Q712 V748E704-K708 WeakPolarHBondContact O-CG 3.39Å; E704-K708 PolarHBondContact O-N 2.98Å; E705-K708 WeakPolarHBondContact O-CB 3.34Å; E705-K708 PolarHBondContact O-N 3.43Å; E705-K708 VanDerWaalsContact O-N 3.11Å; D706-K708 PolarHBondContact O-N 2.92Å; K708-Q712 WeakPolarHBondContact O-CG 3.4Å; K708-Q712 PolarHBondContact O-N 3.11Å; K708-V748 HydrophobicContact CG-CG1 4.36Å
709L91.7Very high90.9Very high106 Ų10653.1 Ų53.156%0.55526%0.256SS*.Hα-helixtrans-66.8-42.6178.3-67.5174.8000111.7E705 D706 R707 Q712 A713E705-L709 PolarHBondContact O-N 3.11Å; E705-L709 VanDerWaalsContact O-N 3.1Å; D706-L709 PolarHBondContact O-N 2.9Å; R707-L709 VanDerWaalsContact C-N 3.34Å; R707-L709 PolarHBondContact O-N 3.27Å; L709-Q712 PolarHBondContact O-N 3.38Å; L709-A713 WeakPolarHBondContact O-CB 3.41Å; L709-A713 PolarHBondContact O-N 3.29Å
710L91.1Very high91.4Very high68 Ų6858.8 Ų58.836%0.35628%0.28SS..Hα-helixtrans-63.8-41.3176.8-74.3172.6000112.3D706 R707 A713 A714 F742D706-L710 WeakPolarHBondContact O-CB 3.46Å; D706-L710 VanDerWaalsContact O-CG 3.31Å; D706-L710 WeakPolarHBondContact O-CG 3.44Å; D706-L710 PolarHBondContact O-N 2.91Å; R707-L710 PolarHBondContact O-N 3.36Å; L710-A713 PolarHBondContact O-N 2.91Å; L710-A714 WeakPolarHBondContact O-CB 3.42Å; L710-A714 PolarHBondContact O-N 3.47Å; L710-F742 HydrophobicContact CD1-CE1 4.35Å
711I94.3Very high91.8Very high2 Ų262.6 Ų62.61%0.0130%0.299CS..Hα-helixtrans-62.8-47175.1-68.1162.5000110.3R707 A713 A714 I715 V734 L738 F742 P744 V748 I749 C752R707-I711 WeakPolarHBondContact O-CB 3.38Å; R707-I711 WeakPolarHBondContact O-CD1 3.35Å; R707-I711 WeakPolarHBondContact O-CG1 3.46Å; R707-I711 PolarHBondContact O-N 3.39Å; I711-A713 PolarHBondContact O-N 3.1Å; I711-A714 PolarHBondContact O-N 3.11Å; I711-I715 HydrophobicContact CG2-CD1 3.7Å; I711-I715 HydrophobicContact CG2-CG1 4.35Å; I711-I715 VanDerWaalsContact O-CG1 3.28Å; I711-I715 WeakPolarHBondContact O-CG1 3.4Å; I711-I715 PolarHBondContact O-N 3.37Å; I711-V734 HydrophobicContact CG2-CG1 4.48Å; I711-L738 HydrophobicContact CB-CD1 4.38Å; I711-L738 HydrophobicContact CG1-CD1 3.63Å; I711-F742 HydrophobicContact CD1-CE2 4.15Å; I711-F742 HydrophobicContact CD1-CZ 4.2Å; I711-F742 HydrophobicContact CG1-CE2 4.35Å; I711-F742 HydrophobicContact CG1-CZ 3.99Å; I711-P744 HydrophobicContact CD1-CB 4.02Å; I711-P744 HydrophobicContact CG1-CB 4.34Å; I711-V748 HydrophobicContact CD1-CB 4.49Å; I711-V748 HydrophobicContact CD1-CG1 3.76Å; I711-I749 HydrophobicContact CG2-CG1 4.31Å; I711-I749 HydrophobicContact CG2-CG2 4.44Å; I711-C752 HydrophobicContact CG2-CB 3.76Å
712Q93.9Very high92.1Very high22 Ų2262.6 Ų62.610%0.10330%0.296CS..Hα-helixtrans-57.7-48.3176.4-75.9173.651.100111.5K708 L709 A714 I715 V716 C752 L756K708-Q712 WeakPolarHBondContact O-CG 3.4Å; K708-Q712 PolarHBondContact O-N 3.11Å; L709-Q712 PolarHBondContact O-N 3.38Å; Q712-A714 VanDerWaalsContact C-N 3.33Å; Q712-A714 PolarHBondContact O-N 3.31Å; Q712-I715 PolarHBondContact O-N 2.9Å; Q712-V716 WeakPolarHBondContact O-CG2 3.28Å; Q712-V716 PolarHBondContact O-N 2.9Å; Q712-C752 HydrophobicContact CG-CB 3.88Å; Q712-L756 HydrophobicContact CB-CD1 4.38Å; Q712-L756 HydrophobicContact CB-CD2 4.27Å; Q712-L756 HydrophobicContact CB-CG 4.47Å; Q712-L756 HydrophobicContact CG-CD1 4.43Å; Q712-L756 HydrophobicContact CG-CD2 4.37Å; Q712-L756 HydrophobicContact CG-CG 4.23Å
713A93.4Very high92.4Very high47 Ų4766 Ų6639%0.38831%0.309SS..Hα-helixtrans-63.3-37.1178.900000112.8L709 L710 I711 R717L709-A713 WeakPolarHBondContact O-CB 3.41Å; L709-A713 PolarHBondContact O-N 3.29Å; L710-A713 PolarHBondContact O-N 2.91Å; I711-A713 PolarHBondContact O-N 3.1Å; A713-R717 WeakPolarHBondContact O-CB 3.37Å; A713-R717 PolarHBondContact O-N 3.35Å
714A94Very high92.6Very high3 Ų369.4 Ų69.43%0.02533%0.33CS..Hα-helixtrans-65.3-48.1175.300000111.5L710 I711 Q712 V716 R717 I718 L738L710-A714 WeakPolarHBondContact O-CB 3.42Å; L710-A714 PolarHBondContact O-N 3.47Å; I711-A714 PolarHBondContact O-N 3.11Å; Q712-A714 VanDerWaalsContact C-N 3.33Å; Q712-A714 PolarHBondContact O-N 3.31Å; A714-V716 PolarHBondContact O-N 3.02Å; A714-R717 PolarHBondContact O-N 3.47Å; A714-I718 WeakPolarHBondContact O-CG1 3.33Å; A714-I718 PolarHBondContact O-N 3.09Å; A714-L738 HydrophobicContact CB-CD1 4.31Å; A714-L738 HydrophobicContact CB-CD2 4.23Å; A714-L738 HydrophobicContact CB-CG 4.32Å
715I95Very high93Very high0 Ų064.2 Ų64.20%031%0.306CS..Hα-helixtrans-57-50.3176.6-67.1161.7000110.4I711 Q712 R717 I718 M719 L730 V734 I749 C752 I753 L756 L762I711-I715 HydrophobicContact CG2-CD1 3.7Å; I711-I715 HydrophobicContact CG2-CG1 4.35Å; I711-I715 VanDerWaalsContact O-CG1 3.28Å; I711-I715 WeakPolarHBondContact O-CG1 3.4Å; I711-I715 PolarHBondContact O-N 3.37Å; Q712-I715 PolarHBondContact O-N 2.9Å; I715-R717 VanDerWaalsContact C-N 3.3Å; I715-R717 PolarHBondContact O-N 2.93Å; I715-I718 PolarHBondContact O-N 2.9Å; I715-M719 HydrophobicContact CG2-CG 4.16Å; I715-M719 WeakPolarHBondContact O-CB 3.33Å; I715-M719 WeakPolarHBondContact O-CG 3.44Å; I715-M719 PolarHBondContact O-N 3.26Å; I715-L730 HydrophobicContact CG2-CD1 4.38Å; I715-L730 HydrophobicContact CG2-CD2 4.26Å; I715-V734 HydrophobicContact CG1-CG2 3.7Å; I715-I749 HydrophobicContact CD1-CG2 4.17Å; I715-C752 HydrophobicContact CD1-CB 3.87Å; I715-I753 HydrophobicContact CD1-CG1 3.91Å; I715-L756 HydrophobicContact CB-CD1 3.68Å; I715-L756 HydrophobicContact CD1-CD1 4.07Å; I715-L756 HydrophobicContact CG2-CD1 3.5Å; I715-L762 HydrophobicContact CG2-CD1 3.73Å
716V95.1Very high93.3Very high29 Ų2964.4 Ų64.418%0.17631%0.305CS..Hα-helixtrans-59.1-42.2179.5170.60000111.1Q712 A714 K720 L756 Y761 Y774Q712-V716 WeakPolarHBondContact O-CG2 3.28Å; Q712-V716 PolarHBondContact O-N 2.9Å; A714-V716 PolarHBondContact O-N 3.02Å; V716-K720 WeakPolarHBondContact O-CB 3.31Å; V716-K720 PolarHBondContact O-N 3.45Å; V716-L756 HydrophobicContact CG2-CD1 3.92Å; V716-L756 HydrophobicContact CG2-CD2 3.59Å; V716-L756 HydrophobicContact CG2-CG 4.39Å; V716-Y761 HydrophobicContact CG1-CD1 4.31Å; V716-Y761 HydrophobicContact CG2-CD1 4.22Å; V716-Y761 HydrophobicContact CG2-CG 4.22Å; V716-Y774 HydrophobicContact CG1-CE2 4.19Å
717R94.3Very high93.5Very high157 Ų15761.7 Ų61.759%0.59229%0.29SS*.Hα-helixtrans-64-44.5178.8-167.9-175.5-53.61583.9112.3A713 A714 I715 M721A713-R717 WeakPolarHBondContact O-CB 3.37Å; A713-R717 PolarHBondContact O-N 3.35Å; A714-R717 PolarHBondContact O-N 3.47Å; I715-R717 VanDerWaalsContact C-N 3.3Å; I715-R717 PolarHBondContact O-N 2.93Å; R717-M721 PolarHBondContact O-N 2.9Å
718I94.5Very high93.6Very high9 Ų967 Ų675%0.04632%0.316CS..Hα-helixtrans-63.1-51.1177.1-71.7161.9000110.1A714 I715 K720 M721 R722 L725 L730 E733 V734A714-I718 WeakPolarHBondContact O-CG1 3.33Å; A714-I718 PolarHBondContact O-N 3.09Å; I715-I718 PolarHBondContact O-N 2.9Å; I718-K720 VanDerWaalsContact C-N 3.35Å; I718-K720 PolarHBondContact O-N 3.41Å; I718-M721 WeakPolarHBondContact O-CB 3.22Å; I718-M721 PolarHBondContact O-N 3.06Å; I718-M721 VanDerWaalsContact O-N 3.08Å; I718-R722 HydrophobicContact CG2-CG 4.28Å; I718-R722 WeakPolarHBondContact O-CG 3.49Å; I718-R722 PolarHBondContact O-N 3.43Å; I718-L725 HydrophobicContact CG2-CD2 3.83Å; I718-L730 HydrophobicContact CB-CD1 4.28Å; I718-L730 HydrophobicContact CG2-CD1 3.73Å; I718-E733 HydrophobicContact CD1-CB 3.81Å; I718-E733 HydrophobicContact CG1-CB 4.39Å; I718-E733 HydrophobicContact CG2-CB 4.29Å; I718-E733 WeakPolarHBondContact CG2-OE2 3.42Å; I718-V734 HydrophobicContact CD1-CB 4.38Å; I718-V734 HydrophobicContact CD1-CG2 3.63Å
719M94.9Very high93.7Very high0 Ų067.4 Ų67.40%032%0.32CS..Hα-helixtrans-65.3-36.9-177.4-72.9-60.5-57.400112.3I715 M721 R722 K723 L725 L730 L762 Y772 Y774I715-M719 HydrophobicContact CG2-CG 4.16Å; I715-M719 WeakPolarHBondContact O-CB 3.33Å; I715-M719 WeakPolarHBondContact O-CG 3.44Å; I715-M719 PolarHBondContact O-N 3.26Å; M719-M721 VanDerWaalsContact C-N 3.25Å; M719-M721 PolarHBondContact O-N 2.97Å; M719-R722 PolarHBondContact O-N 3.27Å; M719-K723 VanDerWaalsContact O-CA 3.24Å; M719-K723 WeakPolarHBondContact O-CA 3.38Å; M719-K723 PolarHBondContact O-N 3.33Å; M719-L725 HydrophobicContact CE-CB 4.49Å; M719-L725 HydrophobicContact SD-CB 3.76Å; M719-L730 HydrophobicContact CG-CD1 4.09Å; M719-L730 HydrophobicContact CG-CD2 4.47Å; M719-L730 HydrophobicContact SD-CD1 4.09Å; M719-L730 HydrophobicContact SD-CD2 4.24Å; M719-L762 HydrophobicContact CB-CD2 3.51Å; M719-L762 HydrophobicContact CE-CD2 3.86Å; M719-L762 HydrophobicContact CG-CD1 4.49Å; M719-L762 HydrophobicContact CG-CD2 3.47Å; M719-L762 VanDerWaalsContact CG-CD2 3.47Å; M719-L762 HydrophobicContact SD-CD2 4.41Å; M719-Y772 VanDerWaalsContact CE-O 3.31Å; M719-Y772 WeakPolarHBondContact CE-O 3.28Å; M719-Y774 HydrophobicContact CB-CD2 3.94Å; M719-Y774 HydrophobicContact CB-CG 4.36Å; M719-Y774 WeakPolarHBondContact O-CB 3.41Å
720K94.7Very high93.8Very high126 Ų12662.3 Ų62.355%0.54829%0.293SS..Hα-helixtrans-59.6-36.4172.6-177.6172-178.7172.80112.8V716 I718 K723 Y774V716-K720 WeakPolarHBondContact O-CB 3.31Å; V716-K720 PolarHBondContact O-N 3.45Å; I718-K720 VanDerWaalsContact C-N 3.35Å; I718-K720 PolarHBondContact O-N 3.41Å; K720-K723 VanDerWaalsContact O-CE 3.28Å; K720-K723 WeakPolarHBondContact O-CE 3.19Å; K720-Y774 HydrophobicContact CB-CD1 4.3Å; K720-Y774 HydrophobicContact CB-CE1 3.78Å; K720-Y774 HydrophobicContact CB-CE2 4.11Å; K720-Y774 HydrophobicContact CD-CE1 4.46Å; K720-Y774 HydrophobicContact CG-CE1 3.76Å
721M93.1Very high93.9Very high129 Ų12959.7 Ų59.764%0.63528%0.279SS*.Hα-helixtrans-79.6-43.8-179.8-173.4179.972.400112.4R717 I718 M719R717-M721 PolarHBondContact O-N 2.9Å; I718-M721 WeakPolarHBondContact O-CB 3.22Å; I718-M721 PolarHBondContact O-N 3.06Å; I718-M721 VanDerWaalsContact O-N 3.08Å; M719-M721 VanDerWaalsContact C-N 3.25Å; M719-M721 PolarHBondContact O-N 2.97Å
722R93.2Very high93.9Very high130 Ų13061.8 Ų61.849%0.49130%0.297SS..Hα-helixtrans-85.9-22.1-175.5-62.8-62.3-165.5-177.74113.8I718 M719 V724 L725 E733I718-R722 HydrophobicContact CG2-CG 4.28Å; I718-R722 WeakPolarHBondContact O-CG 3.49Å; I718-R722 PolarHBondContact O-N 3.43Å; M719-R722 PolarHBondContact O-N 3.27Å; R722-V724 PolarHBondContact O-N 3.21Å; R722-L725 HydrophobicContact CB-CB 4.48Å; R722-L725 HydrophobicContact CB-CD1 4.38Å; R722-L725 HydrophobicContact CG-CD1 4.33Å; R722-L725 HydrophobicContact CG-CD2 4.35Å; R722-E733 IonicContact CZ-OE1 2.82Å; R722-E733 VanDerWaalsContact CZ-OE1 3.29Å; R722-E733 IonicContact NE-OE1 3.85Å; R722-E733 PolarHBondContact NE-OE1 3.45Å; R722-E733 IonicContact NE-OE2 3.62Å; R722-E733 IonicContact NH2-OE1 3.29Å; R722-E733 PolarHBondContact NH2-OE1 3.43Å
723K92.8Very high93.9Very high108 Ų10863 Ų6347%0.4730%0.303SS..SBendtrans63.2-48.4-174.3-58.4-60.2-172175.50114.9M719 K720 S773 Y774M719-K723 VanDerWaalsContact O-CA 3.24Å; M719-K723 WeakPolarHBondContact O-CA 3.38Å; M719-K723 PolarHBondContact O-N 3.33Å; K720-K723 VanDerWaalsContact O-CE 3.28Å; K720-K723 WeakPolarHBondContact O-CE 3.19Å; K723-S773 CarbonylContact O-C 3.56Å; K723-S773 WeakPolarHBondContact O-CA 3.27Å; K723-Y774 HydrophobicContact CD-CD1 4.24Å; K723-Y774 PolarHBondContact O-N 3.4Å
724V92.9Very high93.9Very high78 Ų7860.8 Ų60.847%0.47328%0.284SS..EExtended strand (participates in β ladder)trans-132.7132175.9-178.50000108.9R722 V765 T771 Y772R722-V724 PolarHBondContact O-N 3.21Å; V724-V765 HydrophobicContact CG1-CG2 4.39Å; V724-T771 HydrophobicContact CG1-CG2 3.49Å; V724-T771 VanDerWaalsContact CG1-CG2 3.49Å; V724-Y772 VanDerWaalsContact CA-O 3.28Å; V724-Y772 WeakPolarHBondContact CA-O 3.28Å
725L94.6Very high93.8Very high14 Ų1463.4 Ų63.47%0.07330%0.297CS..EExtended strand (participates in β ladder)trans-149.9141.9-178.7-159.665.2000111.8I718 M719 R722 Q729 L730 Y772I718-L725 HydrophobicContact CG2-CD2 3.83Å; M719-L725 HydrophobicContact CE-CB 4.49Å; M719-L725 HydrophobicContact SD-CB 3.76Å; R722-L725 HydrophobicContact CB-CB 4.48Å; R722-L725 HydrophobicContact CB-CD1 4.38Å; R722-L725 HydrophobicContact CG-CD1 4.33Å; R722-L725 HydrophobicContact CG-CD2 4.35Å; L725-Q729 HydrophobicContact CD1-CB 3.86Å; L725-Q729 HydrophobicContact CD2-CB 4.38Å; L725-Q729 HydrophobicContact CG-CB 3.91Å; L725-L730 HydrophobicContact CD2-CB 3.79Å; L725-L730 HydrophobicContact CD2-CD1 4.03Å; L725-L730 HydrophobicContact CG-CB 4.33Å; L725-Y772 PolarHBondContact N-O 3.45Å; L725-Y772 PolarHBondContact O-N 3.32Å
726K94.9Very high93.6Very high115 Ų11569 Ų6950%0.533%0.327SS..EExtended strand (participates in β ladder)trans-74.8151.3174.3-67.6-172.1175.4-173.40111.4Q728 Q729 L730 D770K726-Q728 PolarHBondContact O-N 2.95Å; K726-Q729 PolarHBondContact O-N 2.78Å; K726-Q729 VanDerWaalsContact O-N 3.09Å; K726-L730 PolarHBondContact O-N 3.07Å; K726-D770 CarbonylContact C-O 3.36Å; K726-D770 WeakPolarHBondContact CA-O 3.35Å
727H92.9Very high93.3Very high21 Ų2170.9 Ų70.910%0.09733%0.334CS..Hα-helixtrans-52.5-50.1-177.1-175.582.3000113Q729 L730 L731 D770 Y772H727-Q729 VanDerWaalsContact C-N 3.32Å; H727-Q729 PolarHBondContact O-N 3.34Å; H727-L730 PolarHBondContact O-N 3.3Å; H727-L731 WeakPolarHBondContact NE2-CD1 3.46Å; H727-L731 WeakPolarHBondContact O-CG 3.43Å; H727-L731 PolarHBondContact O-N 3.09Å; H727-D770 PolarHBondContact N-O 2.85Å; H727-Y772 HydrophobicContact CB-CE2 3.83Å; H727-Y772 AromaticContact ND1-CE2 3.44Å; H727-Y772 WeakPolarHBondContact ND1-CE2 3.31Å; H727-Y772 AromaticContact ND1-CZ 3.63Å; H727-Y772 PolarHBondContact ND1-OH 3.5Å
728Q93.3Very high93.1Very high145 Ų14564.1 Ų64.168%0.67831%0.31SS*.Hα-helixtrans-62.7-38.2-179.3-67-64-20.300112.6K726 A732K726-Q728 PolarHBondContact O-N 2.95Å; Q728-A732 WeakPolarHBondContact O-CB 3.23Å; Q728-A732 PolarHBondContact O-N 2.95Å
729Q93.6Very high92.7Very high106 Ų10667.2 Ų67.250%0.49533%0.332SS..Hα-helixtrans-70.3-41.4177.8-67.9174.6-29.400111.1L725 K726 H727 A732 E733L725-Q729 HydrophobicContact CD1-CB 3.86Å; L725-Q729 HydrophobicContact CD2-CB 4.38Å; L725-Q729 HydrophobicContact CG-CB 3.91Å; K726-Q729 PolarHBondContact O-N 2.78Å; K726-Q729 VanDerWaalsContact O-N 3.09Å; H727-Q729 VanDerWaalsContact C-N 3.32Å; H727-Q729 PolarHBondContact O-N 3.34Å; Q729-A732 PolarHBondContact O-N 2.98Å; Q729-E733 PolarHBondContact O-N 3.42Å
730L93.7Very high92.1Very high0 Ų070.3 Ų70.30%035%0.354CS..Hα-helixtrans-61.2-45.8174.6-179.659.8000111.4I715 I718 M719 L725 K726 H727 A732 E733 V734 I753 Y772I715-L730 HydrophobicContact CG2-CD1 4.38Å; I715-L730 HydrophobicContact CG2-CD2 4.26Å; I718-L730 HydrophobicContact CB-CD1 4.28Å; I718-L730 HydrophobicContact CG2-CD1 3.73Å; M719-L730 HydrophobicContact CG-CD1 4.09Å; M719-L730 HydrophobicContact CG-CD2 4.47Å; M719-L730 HydrophobicContact SD-CD1 4.09Å; M719-L730 HydrophobicContact SD-CD2 4.24Å; L725-L730 HydrophobicContact CD2-CB 3.79Å; L725-L730 HydrophobicContact CD2-CD1 4.03Å; L725-L730 HydrophobicContact CG-CB 4.33Å; K726-L730 PolarHBondContact O-N 3.07Å; H727-L730 PolarHBondContact O-N 3.3Å; L730-A732 VanDerWaalsContact C-N 3.33Å; L730-A732 PolarHBondContact O-N 3.33Å; L730-E733 PolarHBondContact O-N 2.85Å; L730-V734 HydrophobicContact CD1-CG2 4.01Å; L730-V734 HydrophobicContact CG-CG2 4.36Å; L730-V734 WeakPolarHBondContact O-CB 3.32Å; L730-V734 VanDerWaalsContact O-CG2 3.22Å; L730-V734 WeakPolarHBondContact O-CG2 3.49Å; L730-V734 PolarHBondContact O-N 2.95Å; L730-I753 HydrophobicContact CD2-CD1 3.96Å; L730-I753 HydrophobicContact CD2-CG1 4.33Å; L730-Y772 HydrophobicContact CD2-CD2 3.82Å; L730-Y772 HydrophobicContact CD2-CE2 4.18Å
731L93.4Very high91.6Very high13 Ų1367 Ų677%0.06834%0.338CS..Hα-helixtrans-57.7-47175.7-70.9-173.2000111.3H727 V734 L735 V746 I749H727-L731 WeakPolarHBondContact NE2-CD1 3.46Å; H727-L731 WeakPolarHBondContact O-CG 3.43Å; H727-L731 PolarHBondContact O-N 3.09Å; L731-V734 PolarHBondContact O-N 3.29Å; L731-L735 WeakPolarHBondContact O-CB 3.5Å; L731-L735 VanDerWaalsContact O-CG 3.23Å; L731-L735 WeakPolarHBondContact O-CG 3.41Å; L731-L735 PolarHBondContact O-N 3.01Å; L731-V746 HydrophobicContact CD1-CG1 4.03Å; L731-I749 HydrophobicContact CD2-CB 3.98Å; L731-I749 HydrophobicContact CD2-CD1 4.01Å; L731-I749 HydrophobicContact CD2-CG2 3.54Å
732A93.6Very high91.4Very high46 Ų4661 Ų6138%0.3831%0.308SS..Hα-helixtrans-62.1-44.7179.400000112.3Q728 Q729 L730 L735 N736Q728-A732 WeakPolarHBondContact O-CB 3.23Å; Q728-A732 PolarHBondContact O-N 2.95Å; Q729-A732 PolarHBondContact O-N 2.98Å; L730-A732 VanDerWaalsContact C-N 3.33Å; L730-A732 PolarHBondContact O-N 3.33Å; A732-L735 PolarHBondContact O-N 3.41Å; A732-N736 WeakPolarHBondContact O-CB 3.35Å; A732-N736 VanDerWaalsContact O-CG 3.26Å; A732-N736 PolarHBondContact O-N 2.91Å; A732-N736 PolarHBondContact O-ND2 3.4Å
733E94.1Very high91.1Very high47 Ų4760.4 Ų60.422%0.2231%0.309CS..Hα-helixtrans-65.6-41.6177.7-72.1-162.8-174.300112.1I718 R722 Q729 L730 N736 Q737I718-E733 HydrophobicContact CD1-CB 3.81Å; I718-E733 HydrophobicContact CG1-CB 4.39Å; I718-E733 HydrophobicContact CG2-CB 4.29Å; I718-E733 WeakPolarHBondContact CG2-OE2 3.42Å; R722-E733 IonicContact CZ-OE1 2.82Å; R722-E733 VanDerWaalsContact CZ-OE1 3.29Å; R722-E733 IonicContact NE-OE1 3.85Å; R722-E733 PolarHBondContact NE-OE1 3.45Å; R722-E733 IonicContact NE-OE2 3.62Å; R722-E733 IonicContact NH2-OE1 3.29Å; R722-E733 PolarHBondContact NH2-OE1 3.43Å; Q729-E733 PolarHBondContact O-N 3.42Å; L730-E733 PolarHBondContact O-N 2.85Å; E733-N736 PolarHBondContact O-N 3.21Å; E733-Q737 WeakPolarHBondContact O-CB 3.31Å; E733-Q737 PolarHBondContact O-N 2.97Å
734V93.9Very high90.8Very high0 Ų055.7 Ų55.70%029%0.289CS..Hα-helixtrans-63.6-44.6176.81720000111.3I711 I715 I718 L730 L731 Q737 L738 I749I711-V734 HydrophobicContact CG2-CG1 4.48Å; I715-V734 HydrophobicContact CG1-CG2 3.7Å; I718-V734 HydrophobicContact CD1-CB 4.38Å; I718-V734 HydrophobicContact CD1-CG2 3.63Å; L730-V734 HydrophobicContact CD1-CG2 4.01Å; L730-V734 HydrophobicContact CG-CG2 4.36Å; L730-V734 WeakPolarHBondContact O-CB 3.32Å; L730-V734 VanDerWaalsContact O-CG2 3.22Å; L730-V734 WeakPolarHBondContact O-CG2 3.49Å; L730-V734 PolarHBondContact O-N 2.95Å; L731-V734 PolarHBondContact O-N 3.29Å; V734-Q737 PolarHBondContact O-N 3.38Å; V734-L738 HydrophobicContact CG1-CD1 3.9Å; V734-L738 WeakPolarHBondContact O-CB 3.4Å; V734-L738 WeakPolarHBondContact O-CG 3.44Å; V734-L738 PolarHBondContact O-N 2.99Å; V734-L738 VanDerWaalsContact O-N 3.1Å; V734-I749 HydrophobicContact CG1-CD1 4.06Å; V734-I749 HydrophobicContact CG1-CG1 4.36Å; V734-I749 HydrophobicContact CG1-CG2 4.39Å
735L91.4Very high90.5Very high58 Ų5859.9 Ų59.930%0.30430%0.297SS..Hα-helixtrans-61.8-45.5177.1-73174.1000111.2L731 A732 L738 S739 P744 I749L731-L735 WeakPolarHBondContact O-CB 3.5Å; L731-L735 VanDerWaalsContact O-CG 3.23Å; L731-L735 WeakPolarHBondContact O-CG 3.41Å; L731-L735 PolarHBondContact O-N 3.01Å; A732-L735 PolarHBondContact O-N 3.41Å; L735-L738 PolarHBondContact O-N 3.45Å; L735-S739 WeakPolarHBondContact O-CB 3.23Å; L735-S739 PolarHBondContact O-N 3.37Å; L735-P744 HydrophobicContact CD2-CB 4.28Å; L735-P744 HydrophobicContact CD2-CG 4.2Å; L735-P744 WeakPolarHBondContact CD2-O 3.47Å; L735-I749 HydrophobicContact CD2-CD1 4.07Å; L735-I749 HydrophobicContact CG-CD1 4.32Å
736N90.6Very high90.2Very high118 Ų11862 Ų6263%0.63131%0.31SS*.Hα-helixtrans-62.8-45.8178.5-76.3-19.9000111.7A732 E733 L738 S739A732-N736 WeakPolarHBondContact O-CB 3.35Å; A732-N736 VanDerWaalsContact O-CG 3.26Å; A732-N736 PolarHBondContact O-N 2.91Å; A732-N736 PolarHBondContact O-ND2 3.4Å; E733-N736 PolarHBondContact O-N 3.21Å; N736-L738 VanDerWaalsContact C-N 3.33Å; N736-L738 PolarHBondContact O-N 2.95Å; N736-S739 PolarHBondContact O-OG 3.48Å
737Q89.8Confident90.1Very high69 Ų6960.6 Ų60.632%0.32231%0.313SS..Hα-helixtrans-64.3-36.2-178.8-171.9175.420.700112.9E733 V734E733-Q737 WeakPolarHBondContact O-CB 3.31Å; E733-Q737 PolarHBondContact O-N 2.97Å; V734-Q737 PolarHBondContact O-N 3.38Å
738L89.4Confident89.9Confident15 Ų1561.9 Ų61.98%0.07932%0.322CS..Hα-helixtrans-92-14.2-176.4-64.8177000114.2I711 A714 V734 L735 N736 S740 R741 F742 P744I711-L738 HydrophobicContact CB-CD1 4.38Å; I711-L738 HydrophobicContact CG1-CD1 3.63Å; A714-L738 HydrophobicContact CB-CD1 4.31Å; A714-L738 HydrophobicContact CB-CD2 4.23Å; A714-L738 HydrophobicContact CB-CG 4.32Å; V734-L738 HydrophobicContact CG1-CD1 3.9Å; V734-L738 WeakPolarHBondContact O-CB 3.4Å; V734-L738 WeakPolarHBondContact O-CG 3.44Å; V734-L738 PolarHBondContact O-N 2.99Å; V734-L738 VanDerWaalsContact O-N 3.1Å; L735-L738 PolarHBondContact O-N 3.45Å; N736-L738 VanDerWaalsContact C-N 3.33Å; N736-L738 PolarHBondContact O-N 2.95Å; L738-S740 PolarHBondContact O-N 2.89Å; L738-R741 PolarHBondContact O-N 3.08Å; L738-F742 CarbonylContact C-O 3.48Å; L738-F742 HydrophobicContact CD1-CZ 4.07Å; L738-F742 HydrophobicContact CD2-CE1 4.48Å; L738-F742 PolarHBondContact O-N 2.83Å; L738-F742 VanDerWaalsContact O-N 3.08Å; L738-P744 HydrophobicContact CB-CG 3.77Å; L738-P744 HydrophobicContact CD1-CG 3.6Å; L738-P744 HydrophobicContact CG-CG 4.33Å
739S84.9Confident89.9Confident74 Ų7455 Ų5552%0.51729%0.29SS..THydrogen-bonded Turntrans-52.3-28.1-176.364.40000115.4L735 N736 R741L735-S739 WeakPolarHBondContact O-CB 3.23Å; L735-S739 PolarHBondContact O-N 3.37Å; N736-S739 PolarHBondContact O-OG 3.48Å; S739-R741 VanDerWaalsContact C-N 3.27Å; S739-R741 PolarHBondContact O-N 3.3Å
740S82.7Confident89.8Confident64 Ų6454.9 Ų54.945%0.44829%0.288SS..THydrogen-bonded Turntrans-70.8-20.9177.761.60000113.6L738L738-S740 PolarHBondContact O-N 2.89Å
741R84.6Confident89.8Confident57 Ų5761.8 Ų61.822%0.21532%0.318CS..THydrogen-bonded Turntrans-110.8-46.9-177.4-62.7-161.3-178.3-149.88.4113.1K459 D460 E499 L738 S739K459-R741 WeakPolarHBondContact CA-O 3.5Å; K459-R741 WeakPolarHBondContact CB-O 3.34Å; K459-R741 PolarHBondContact N-O 3.36Å; D460-R741 PolarHBondContact N-O 3.27Å; E499-R741 IonicContact OE2-NH2 3.42Å; E499-R741 PolarHBondContact OE2-NH2 2.78Å; L738-R741 PolarHBondContact O-N 3.08Å; S739-R741 VanDerWaalsContact C-N 3.27Å; S739-R741 PolarHBondContact O-N 3.3Å
742F89.2Confident89.9Confident3 Ų361.3 Ų61.31%0.01332%0.315CS..  trans-161.4170.5177.566.9-83.6000110.5E457 D460 R707 L710 I711 L738 P744E457-F742 WeakPolarHBondContact O-CA 3.32Å; D460-F742 WeakPolarHBondContact OD1-CB 3.44Å; R707-F742 HydrophobicContact CB-CE1 4.49Å; R707-F742 HydrophobicContact CB-CE2 4.12Å; R707-F742 HydrophobicContact CB-CZ 3.91Å; R707-F742 HydrophobicContact CG-CD1 4.25Å; R707-F742 HydrophobicContact CG-CD2 4.16Å; R707-F742 HydrophobicContact CG-CE1 3.95Å; R707-F742 HydrophobicContact CG-CE2 3.83Å; R707-F742 HydrophobicContact CG-CG 4.37Å; R707-F742 HydrophobicContact CG-CZ 3.72Å; L710-F742 HydrophobicContact CD1-CE1 4.35Å; I711-F742 HydrophobicContact CD1-CE2 4.15Å; I711-F742 HydrophobicContact CD1-CZ 4.2Å; I711-F742 HydrophobicContact CG1-CE2 4.35Å; I711-F742 HydrophobicContact CG1-CZ 3.99Å; L738-F742 CarbonylContact C-O 3.48Å; L738-F742 HydrophobicContact CD1-CZ 4.07Å; L738-F742 HydrophobicContact CD2-CE1 4.48Å; L738-F742 PolarHBondContact O-N 2.83Å; L738-F742 VanDerWaalsContact O-N 3.08Å; F742-P744 HydrophobicContact CD2-CB 4.45Å; F742-P744 HydrophobicContact CD2-CG 4.11Å; F742-P744 HydrophobicContact CE2-CB 3.87Å; F742-P744 HydrophobicContact CE2-CG 3.65Å; F742-P744 HydrophobicContact CZ-CG 4.25Å; F742-P744 VanDerWaalsContact O-CD 3.31Å; F742-P744 WeakPolarHBondContact O-CD 3.24Å
743K86Confident89.9Confident118 Ų11859.1 Ų59.151%0.51330%0.297SS..  trans-102.8101.8176-168.4176.9-170.7174.40110.4E457 R745E457-K743 IonicContact OE1-NZ 3.58Å; E457-K743 PolarHBondContact OE1-NZ 3.04Å; E457-K743 WeakPolarHBondContact OE2-CD 3.47Å; E457-K743 IonicContact OE2-NZ 2.9Å; K743-R745 PolarHBondContact O-N 3.07Å
744P86.9Confident89.8Confident8 Ų860.1 Ų60.15%0.05230%0.304CS..  trans-64.6137.4-178.1-15.526000111.7I711 L735 L738 F742 I749I711-P744 HydrophobicContact CD1-CB 4.02Å; I711-P744 HydrophobicContact CG1-CB 4.34Å; L735-P744 HydrophobicContact CD2-CB 4.28Å; L735-P744 HydrophobicContact CD2-CG 4.2Å; L735-P744 WeakPolarHBondContact CD2-O 3.47Å; L738-P744 HydrophobicContact CB-CG 3.77Å; L738-P744 HydrophobicContact CD1-CG 3.6Å; L738-P744 HydrophobicContact CG-CG 4.33Å; F742-P744 HydrophobicContact CD2-CB 4.45Å; F742-P744 HydrophobicContact CD2-CG 4.11Å; F742-P744 HydrophobicContact CE2-CB 3.87Å; F742-P744 HydrophobicContact CE2-CG 3.65Å; F742-P744 HydrophobicContact CZ-CG 4.25Å; F742-P744 VanDerWaalsContact O-CD 3.31Å; F742-P744 WeakPolarHBondContact O-CD 3.24Å; P744-I749 HydrophobicContact CB-CD1 4.01Å; P744-I749 HydrophobicContact CB-CG1 3.99Å
745R87Confident89.8Confident167 Ų16762.7 Ų62.763%0.6332%0.317SS*.  trans-77130.9172.6-61.4-177-176.6177.62.3109.5K743 P747 V748 I749K743-R745 PolarHBondContact O-N 3.07Å; R745-P747 VanDerWaalsContact C-CD 3.43Å; R745-P747 VanDerWaalsContact C-N 3.32Å; R745-V748 HydrophobicContact CB-CG2 4.12Å; R745-V748 WeakPolarHBondContact O-CA 3.25Å; R745-V748 WeakPolarHBondContact O-CB 3.44Å; R745-V748 PolarHBondContact O-N 3.3Å; R745-I749 PolarHBondContact O-N 3.06Å
746V89.3Confident89.9Confident58 Ų5860 Ų6035%0.35230%0.303SS..Hα-helixtrans-50.6-42.1179.9178.80000113.5L731 V748 I749 K750L731-V746 HydrophobicContact CD1-CG1 4.03Å; V746-V748 PolarHBondContact O-N 2.61Å; V746-I749 PolarHBondContact O-N 3.43Å; V746-K750 PolarHBondContact O-N 3.01Å
747P91.3Very high90Very high86 Ų8656.7 Ų56.756%0.55829%0.285SS*.Hα-helixtrans-59.9-31.8175.8-25.635.7000114.3R745 K751R745-P747 VanDerWaalsContact C-CD 3.43Å; R745-P747 VanDerWaalsContact C-N 3.32Å; P747-K751 WeakPolarHBondContact O-CG 3.44Å; P747-K751 PolarHBondContact O-N 2.91Å
748V90.2Very high90.2Very high47 Ų4760.9 Ų60.929%0.28530%0.304SS..Hα-helixtrans-73.7-40.7177.8-178.20000110.2K708 I711 R745 V746 K750 K751 C752K708-V748 HydrophobicContact CG-CG1 4.36Å; I711-V748 HydrophobicContact CD1-CB 4.49Å; I711-V748 HydrophobicContact CD1-CG1 3.76Å; R745-V748 HydrophobicContact CB-CG2 4.12Å; R745-V748 WeakPolarHBondContact O-CA 3.25Å; R745-V748 WeakPolarHBondContact O-CB 3.44Å; R745-V748 PolarHBondContact O-N 3.3Å; V746-V748 PolarHBondContact O-N 2.61Å; V748-K750 VanDerWaalsContact C-N 3.32Å; V748-K750 PolarHBondContact O-N 2.77Å; V748-K751 PolarHBondContact O-N 3.36Å; V748-C752 PolarHBondContact O-N 2.95Å; V748-C752 PolarHBondContact O-SG 2.89Å
749I92.8Very high90.4Very high0 Ų065.4 Ų65.40%032%0.323CS..Hα-helixtrans-59.3-45.3174.9-54.1173.7000110.3I711 I715 L731 V734 L735 P744 R745 V746 K751 C752 I753I711-I749 HydrophobicContact CG2-CG1 4.31Å; I711-I749 HydrophobicContact CG2-CG2 4.44Å; I715-I749 HydrophobicContact CD1-CG2 4.17Å; L731-I749 HydrophobicContact CD2-CB 3.98Å; L731-I749 HydrophobicContact CD2-CD1 4.01Å; L731-I749 HydrophobicContact CD2-CG2 3.54Å; V734-I749 HydrophobicContact CG1-CD1 4.06Å; V734-I749 HydrophobicContact CG1-CG1 4.36Å; V734-I749 HydrophobicContact CG1-CG2 4.39Å; L735-I749 HydrophobicContact CD2-CD1 4.07Å; L735-I749 HydrophobicContact CG-CD1 4.32Å; P744-I749 HydrophobicContact CB-CD1 4.01Å; P744-I749 HydrophobicContact CB-CG1 3.99Å; R745-I749 PolarHBondContact O-N 3.06Å; V746-I749 PolarHBondContact O-N 3.43Å; I749-K751 PolarHBondContact O-N 2.86Å; I749-C752 WeakPolarHBondContact O-CB 3.34Å; I749-C752 PolarHBondContact O-N 2.98Å; I749-C752 VanDerWaalsContact O-N 3.11Å; I749-I753 HydrophobicContact CG2-CD1 4.16Å; I749-I753 HydrophobicContact CG2-CG1 4.5Å; I749-I753 WeakPolarHBondContact O-CG1 3.36Å; I749-I753 PolarHBondContact O-N 2.98Å
750K91.8Very high90.7Very high105 Ų10569.1 Ų69.146%0.45733%0.333SS..Hα-helixtrans-56.9-50.3176.6-71-177.1177.2-172.80112V746 V748 C752 I753 D754V746-K750 PolarHBondContact O-N 3.01Å; V748-K750 VanDerWaalsContact C-N 3.32Å; V748-K750 PolarHBondContact O-N 2.77Å; K750-C752 VanDerWaalsContact C-N 3.27Å; K750-C752 PolarHBondContact O-N 3.47Å; K750-I753 WeakPolarHBondContact O-CB 3.44Å; K750-I753 PolarHBondContact O-N 3.08Å; K750-I753 VanDerWaalsContact O-N 3.07Å; K750-D754 PolarHBondContact O-N 2.85Å
751K93.8Very high91.1Very high145 Ų14570.9 Ų70.963%0.6333%0.33SS*.Hα-helixtrans-57.5-39.1174.8-72.4-177.8179.1-172.60112.5P747 V748 I749 D754 I755P747-K751 WeakPolarHBondContact O-CG 3.44Å; P747-K751 PolarHBondContact O-N 2.91Å; V748-K751 PolarHBondContact O-N 3.36Å; I749-K751 PolarHBondContact O-N 2.86Å; K751-D754 PolarHBondContact O-N 2.87Å; K751-I755 WeakPolarHBondContact O-CD1 3.47Å; K751-I755 VanDerWaalsContact O-CG1 3.25Å; K751-I755 WeakPolarHBondContact O-CG1 3.17Å; K751-I755 PolarHBondContact O-N 2.79Å
752C94.5Very high91.5Very high2 Ų268.2 Ų68.21%0.01432%0.32CS..Hα-helixtrans-67.6-35.5176.5-69.20000112.8I711 Q712 I715 V748 I749 K750 L756I711-C752 HydrophobicContact CG2-CB 3.76Å; Q712-C752 HydrophobicContact CG-CB 3.88Å; I715-C752 HydrophobicContact CD1-CB 3.87Å; V748-C752 PolarHBondContact O-N 2.95Å; V748-C752 PolarHBondContact O-SG 2.89Å; I749-C752 WeakPolarHBondContact O-CB 3.34Å; I749-C752 PolarHBondContact O-N 2.98Å; I749-C752 VanDerWaalsContact O-N 3.11Å; K750-C752 VanDerWaalsContact C-N 3.27Å; K750-C752 PolarHBondContact O-N 3.47Å; C752-L756 WeakPolarHBondContact O-CB 3.34Å; C752-L756 VanDerWaalsContact O-CG 3.24Å; C752-L756 WeakPolarHBondContact O-CG 3.33Å; C752-L756 PolarHBondContact O-N 3.32Å
753I93.3Very high91.6Very high1 Ų172 Ų721%0.00534%0.338CS..Hα-helixtrans-64-47173.4-66.5166.8000109.8I715 L730 I749 K750 I755 L756 I757 Y772I715-I753 HydrophobicContact CD1-CG1 3.91Å; L730-I753 HydrophobicContact CD2-CD1 3.96Å; L730-I753 HydrophobicContact CD2-CG1 4.33Å; I749-I753 HydrophobicContact CG2-CD1 4.16Å; I749-I753 HydrophobicContact CG2-CG1 4.5Å; I749-I753 WeakPolarHBondContact O-CG1 3.36Å; I749-I753 PolarHBondContact O-N 2.98Å; K750-I753 WeakPolarHBondContact O-CB 3.44Å; K750-I753 PolarHBondContact O-N 3.08Å; K750-I753 VanDerWaalsContact O-N 3.07Å; I753-I755 VanDerWaalsContact C-N 3.33Å; I753-I755 PolarHBondContact O-N 3.34Å; I753-L756 PolarHBondContact O-N 3.42Å; I753-I757 HydrophobicContact CG2-CD1 3.91Å; I753-I757 HydrophobicContact CG2-CG1 4.43Å; I753-I757 WeakPolarHBondContact O-CG1 3.44Å; I753-I757 PolarHBondContact O-N 2.8Å; I753-Y772 HydrophobicContact CD1-CE2 4.26Å; I753-Y772 HydrophobicContact CG2-CD1 4.29Å; I753-Y772 HydrophobicContact CG2-CE1 3.76Å; I753-Y772 HydrophobicContact CG2-CE2 4.36Å
754D92.9Very high91.9Very high67 Ų6772 Ų7236%0.35834%0.335SS..Hα-helixtrans-59-45.2179.2-61.8-36.3000111K750 K751 L756 I757 E758 R764K750-D754 PolarHBondContact O-N 2.85Å; K751-D754 PolarHBondContact O-N 2.87Å; D754-L756 VanDerWaalsContact C-N 3.29Å; D754-L756 PolarHBondContact O-N 3.48Å; D754-I757 PolarHBondContact O-N 3.4Å; D754-E758 WeakPolarHBondContact O-CG 3.24Å; D754-E758 PolarHBondContact O-N 2.97Å; D754-R764 IonicContact OD1-NH2 3.69Å
755I93.6Very high92.1Very high54 Ų5473.8 Ų73.828%0.27735%0.346SS..Hα-helixtrans-59.9-37.5174.2-68.2164.3000112.1K751 I753 K759K751-I755 WeakPolarHBondContact O-CD1 3.47Å; K751-I755 VanDerWaalsContact O-CG1 3.25Å; K751-I755 WeakPolarHBondContact O-CG1 3.17Å; K751-I755 PolarHBondContact O-N 2.79Å; I753-I755 VanDerWaalsContact C-N 3.33Å; I753-I755 PolarHBondContact O-N 3.34Å; I755-K759 HydrophobicContact CG2-CD 4.01Å; I755-K759 WeakPolarHBondContact O-CB 3.41Å; I755-K759 VanDerWaalsContact O-CG 3.25Å; I755-K759 WeakPolarHBondContact O-CG 3.36Å; I755-K759 PolarHBondContact O-N 3.18Å
756L94.3Very high91.8Very high3 Ų373.6 Ų73.62%0.01636%0.357CS..Hα-helixtrans-75-27.2179.6-73.9173.2000112.8Q712 I715 V716 C752 I753 D754 E760 Y761 L762Q712-L756 HydrophobicContact CB-CD1 4.38Å; Q712-L756 HydrophobicContact CB-CD2 4.27Å; Q712-L756 HydrophobicContact CB-CG 4.47Å; Q712-L756 HydrophobicContact CG-CD1 4.43Å; Q712-L756 HydrophobicContact CG-CD2 4.37Å; Q712-L756 HydrophobicContact CG-CG 4.23Å; I715-L756 HydrophobicContact CB-CD1 3.68Å; I715-L756 HydrophobicContact CD1-CD1 4.07Å; I715-L756 HydrophobicContact CG2-CD1 3.5Å; V716-L756 HydrophobicContact CG2-CD1 3.92Å; V716-L756 HydrophobicContact CG2-CD2 3.59Å; V716-L756 HydrophobicContact CG2-CG 4.39Å; C752-L756 WeakPolarHBondContact O-CB 3.34Å; C752-L756 VanDerWaalsContact O-CG 3.24Å; C752-L756 WeakPolarHBondContact O-CG 3.33Å; C752-L756 PolarHBondContact O-N 3.32Å; I753-L756 PolarHBondContact O-N 3.42Å; D754-L756 VanDerWaalsContact C-N 3.29Å; D754-L756 PolarHBondContact O-N 3.48Å; L756-E760 PolarHBondContact O-N 2.92Å; L756-Y761 HydrophobicContact CD2-CD2 3.88Å; L756-Y761 HydrophobicContact CD2-CG 4.21Å; L756-Y761 PolarHBondContact O-N 3.04Å; L756-L762 HydrophobicContact CB-CD1 3.77Å; L756-L762 HydrophobicContact CB-CG 4.18Å; L756-L762 HydrophobicContact CD1-CD1 4.08Å; L756-L762 PolarHBondContact O-N 3Å
757I92.8Very high91.2Very high48 Ų4875.1 Ų75.125%0.24638%0.384CS..Hα-helixtrans-70.2-46.3170.4-66.2167.1000109.8I753 D754 K759 E760 L762 R764 Y772I753-I757 HydrophobicContact CG2-CD1 3.91Å; I753-I757 HydrophobicContact CG2-CG1 4.43Å; I753-I757 WeakPolarHBondContact O-CG1 3.44Å; I753-I757 PolarHBondContact O-N 2.8Å; D754-I757 PolarHBondContact O-N 3.4Å; I757-K759 PolarHBondContact O-N 3.11Å; I757-E760 PolarHBondContact O-N 3.05Å; I757-L762 WeakPolarHBondContact CA-O 3.28Å; I757-L762 HydrophobicContact CG1-CB 3.97Å; I757-R764 HydrophobicContact CD1-CG 4.15Å; I757-Y772 HydrophobicContact CD1-CD1 4.4Å; I757-Y772 HydrophobicContact CD1-CE1 4.19Å
758E93.1Very high91Very high156 Ų15675.6 Ų75.673%0.72938%0.379SS*.Hα-helixtrans-59.4-32.8175.3-71.6173.9-177.700112.8D754 E760D754-E758 WeakPolarHBondContact O-CG 3.24Å; D754-E758 PolarHBondContact O-N 2.97Å; E758-E760 VanDerWaalsContact C-N 3.27Å; E758-E760 PolarHBondContact O-N 3.38Å
759K93.3Very high90.5Very high110 Ų11081.4 Ų81.448%0.47840%0.4SS..THydrogen-bonded Turntrans-85.88.5176-70.9177.7-179.9-179.40114I755 I757 Y761I755-K759 HydrophobicContact CG2-CD 4.01Å; I755-K759 WeakPolarHBondContact O-CB 3.41Å; I755-K759 VanDerWaalsContact O-CG 3.25Å; I755-K759 WeakPolarHBondContact O-CG 3.36Å; I755-K759 PolarHBondContact O-N 3.18Å; I757-K759 PolarHBondContact O-N 3.11Å; K759-Y761 HydrophobicContact CB-CD2 3.69Å; K759-Y761 HydrophobicContact CB-CE2 4.01Å; K759-Y761 HydrophobicContact CD-CE2 4.44Å; K759-Y761 PolarHBondContact O-N 3.38Å; K759-Y761 VanDerWaalsContact O-N 3.15Å
760E91.8Very high90.3Very high152 Ų15286.7 Ų86.771%0.7143%0.429SS*.THydrogen-bonded Turntrans59.424.9177.6-53.8-178.7159.500114.4L756 I757 E758 L775L756-E760 PolarHBondContact O-N 2.92Å; I757-E760 PolarHBondContact O-N 3.05Å; E758-E760 VanDerWaalsContact C-N 3.27Å; E758-E760 PolarHBondContact O-N 3.38Å; E760-L775 HydrophobicContact CB-CD1 4.47Å; E760-L775 WeakPolarHBondContact O-CB 3.46Å
761Y90.7Very high90.3Very high101 Ų10182.1 Ų82.140%0.39641%0.41SS..SBendtrans-82.4-26.6170.1-76.7-79.3000112.1V716 L756 K759 Y774 L775 A776V716-Y761 HydrophobicContact CG1-CD1 4.31Å; V716-Y761 HydrophobicContact CG2-CD1 4.22Å; V716-Y761 HydrophobicContact CG2-CG 4.22Å; L756-Y761 HydrophobicContact CD2-CD2 3.88Å; L756-Y761 HydrophobicContact CD2-CG 4.21Å; L756-Y761 PolarHBondContact O-N 3.04Å; K759-Y761 HydrophobicContact CB-CD2 3.69Å; K759-Y761 HydrophobicContact CB-CE2 4.01Å; K759-Y761 HydrophobicContact CD-CE2 4.44Å; K759-Y761 PolarHBondContact O-N 3.38Å; K759-Y761 VanDerWaalsContact O-N 3.15Å; Y761-Y774 VanDerWaalsContact O-CD2 3.27Å; Y761-Y774 WeakPolarHBondContact O-CD2 2.83Å; Y761-L775 PolarHBondContact O-N 2.93Å; Y761-L775 VanDerWaalsContact O-N 3.13Å; Y761-A776 HydrophobicContact CD1-CB 4.44Å
762L92.8Very high90.3Very high1 Ų175.7 Ų75.71%0.00538%0.381CS..EExtended strand (participates in β ladder)trans-137.5152.1-175.6-57.3173.5000110.3I715 M719 L756 I757 S773 Y774I715-L762 HydrophobicContact CG2-CD1 3.73Å; M719-L762 HydrophobicContact CB-CD2 3.51Å; M719-L762 HydrophobicContact CE-CD2 3.86Å; M719-L762 HydrophobicContact CG-CD1 4.49Å; M719-L762 HydrophobicContact CG-CD2 3.47Å; M719-L762 VanDerWaalsContact CG-CD2 3.47Å; M719-L762 HydrophobicContact SD-CD2 4.41Å; L756-L762 HydrophobicContact CB-CD1 3.77Å; L756-L762 HydrophobicContact CB-CG 4.18Å; L756-L762 HydrophobicContact CD1-CD1 4.08Å; L756-L762 PolarHBondContact O-N 3Å; I757-L762 WeakPolarHBondContact CA-O 3.28Å; I757-L762 HydrophobicContact CG1-CB 3.97Å; L762-S773 CarbonylContact C-O 3.55Å; L762-S773 VanDerWaalsContact CA-O 3.27Å; L762-S773 WeakPolarHBondContact CA-O 3.25Å; L762-Y774 HydrophobicContact CD2-CD2 4.1Å
763E92.4Very high90.2Very high84 Ų8476.6 Ų76.639%0.39339%0.388SS..EExtended strand (participates in β ladder)trans-130.8162166.964.5-176.6173.900110.8Y772 S773 L775E763-Y772 CarbonylContact O-C 3.54Å; E763-Y772 VanDerWaalsContact O-CA 3.28Å; E763-Y772 WeakPolarHBondContact O-CA 3.44Å; E763-S773 PolarHBondContact N-O 3.27Å; E763-S773 PolarHBondContact O-N 2.97Å; E763-S773 PolarHBondContact OE1-OG 3.03Å; E763-L775 HydrophobicContact CB-CD1 3.92Å; E763-L775 HydrophobicContact CB-CD2 4.24Å; E763-L775 HydrophobicContact CB-CG 4.07Å; E763-L775 HydrophobicContact CG-CD1 4.4Å; E763-L775 HydrophobicContact CG-CD2 3.85Å; E763-L775 HydrophobicContact CG-CG 3.99Å; E763-L775 WeakPolarHBondContact OE2-CD2 3.39Å
764R92.3Very high90.3Very high116 Ų11677.9 Ų77.944%0.43839%0.393SS..EExtended strand (participates in β ladder)trans-88.2133.2168-62.7-174.6-174.6-151.45108D754 I757 Y772D754-R764 IonicContact OD1-NH2 3.69Å; I757-R764 HydrophobicContact CD1-CG 4.15Å; R764-Y772 HydrophobicContact CG-CD1 4.13Å; R764-Y772 HydrophobicContact CG-CE1 4.06Å
765V89.4Confident90Very high47 Ų4778.5 Ų78.529%0.28540%0.396SS..PPolyproline II helixtrans-67.5134.4178.7178.80000109.7V724 G767 E768 T771V724-V765 HydrophobicContact CG1-CG2 4.39Å; V765-G767 PolarHBondContact O-N 3.15Å; V765-E768 CarbonylContact O-C 3.57Å; V765-E768 PolarHBondContact O-N 2.9Å; V765-T771 HydrophobicContact CB-CG2 4.22Å; V765-T771 HydrophobicContact CG2-CG2 3.72Å; V765-T771 PolarHBondContact N-O 3.31Å
766D80.9Confident88.9Confident163 Ų16380.5 Ų80.587%0.87242%0.42SS*.THydrogen-bonded Turntrans-57.8127.2178.1-75.1-32.9000111.3E768D766-E768 VanDerWaalsContact C-N 3.31Å; D766-E768 PolarHBondContact O-N 2.86Å
767G77.8Confident88.6Confident89 Ų8984.4 Ų84.492%0.91844%0.44SS*.THydrogen-bonded Turntrans85.7-13.9-177.500000115.4V765V765-G767 PolarHBondContact O-N 3.15Å
768E85.9Confident88.4Confident97 Ų9786.3 Ų86.345%0.45345%0.451SS..  trans-127.392.2-179.7-67-166.517500112.5V765 D766 D770 T771V765-E768 CarbonylContact O-C 3.57Å; V765-E768 PolarHBondContact O-N 2.9Å; D766-E768 VanDerWaalsContact C-N 3.31Å; D766-E768 PolarHBondContact O-N 2.86Å; E768-D770 PolarHBondContact O-N 3.13Å; E768-T771 PolarHBondContact O-N 3.06Å; E768-T771 VanDerWaalsContact O-N 3.11Å; E768-T771 WeakPolarHBondContact OE2-CB 3.27Å; E768-T771 PolarHBondContact OE2-OG1 3.44Å
769K80.2Confident88.1Confident168 Ų16882.4 Ų82.473%0.7344%0.435SS*.THydrogen-bonded Turntrans-60.8-20.4-178-70.8-174178.4179.80115.1
770D88.9Confident87.8Confident112 Ų11280.8 Ų80.860%0.59943%0.433SS*.THydrogen-bonded Turntrans-100.27.9-177.6-69-24.6000113.3K726 H727 E768K726-D770 CarbonylContact C-O 3.36Å; K726-D770 WeakPolarHBondContact CA-O 3.35Å; H727-D770 PolarHBondContact N-O 2.85Å; E768-D770 PolarHBondContact O-N 3.13Å
771T91.8Very high87.6Confident8 Ų876.3 Ų76.35%0.04942%0.415CS..EExtended strand (participates in β ladder)trans-118.8129.2-178.7-57.20000110V724 V765 E768V724-T771 HydrophobicContact CG1-CG2 3.49Å; V724-T771 VanDerWaalsContact CG1-CG2 3.49Å; V765-T771 HydrophobicContact CB-CG2 4.22Å; V765-T771 HydrophobicContact CG2-CG2 3.72Å; V765-T771 PolarHBondContact N-O 3.31Å; E768-T771 PolarHBondContact O-N 3.06Å; E768-T771 VanDerWaalsContact O-N 3.11Å; E768-T771 WeakPolarHBondContact OE2-CB 3.27Å; E768-T771 PolarHBondContact OE2-OG1 3.44Å
772Y93.9Very high87.4Confident10 Ų1074.7 Ų74.74%0.03942%0.417CS..EExtended strand (participates in β ladder)trans-108143.1178-54.6-68.2000110.6M719 V724 L725 H727 L730 I753 I757 E763 R764M719-Y772 VanDerWaalsContact CE-O 3.31Å; M719-Y772 WeakPolarHBondContact CE-O 3.28Å; V724-Y772 VanDerWaalsContact CA-O 3.28Å; V724-Y772 WeakPolarHBondContact CA-O 3.28Å; L725-Y772 PolarHBondContact N-O 3.45Å; L725-Y772 PolarHBondContact O-N 3.32Å; H727-Y772 HydrophobicContact CB-CE2 3.83Å; H727-Y772 AromaticContact ND1-CE2 3.44Å; H727-Y772 WeakPolarHBondContact ND1-CE2 3.31Å; H727-Y772 AromaticContact ND1-CZ 3.63Å; H727-Y772 PolarHBondContact ND1-OH 3.5Å; L730-Y772 HydrophobicContact CD2-CD2 3.82Å; L730-Y772 HydrophobicContact CD2-CE2 4.18Å; I753-Y772 HydrophobicContact CD1-CE2 4.26Å; I753-Y772 HydrophobicContact CG2-CD1 4.29Å; I753-Y772 HydrophobicContact CG2-CE1 3.76Å; I753-Y772 HydrophobicContact CG2-CE2 4.36Å; I757-Y772 HydrophobicContact CD1-CD1 4.4Å; I757-Y772 HydrophobicContact CD1-CE1 4.19Å; E763-Y772 CarbonylContact O-C 3.54Å; E763-Y772 VanDerWaalsContact O-CA 3.28Å; E763-Y772 WeakPolarHBondContact O-CA 3.44Å; R764-Y772 HydrophobicContact CG-CD1 4.13Å; R764-Y772 HydrophobicContact CG-CE1 4.06Å
773S92.4Very high87Confident22 Ų2279.9 Ų79.915%0.15445%0.446CS..EExtended strand (participates in β ladder)trans-115.9146.7172174.10000109.7K723 L762 E763K723-S773 CarbonylContact O-C 3.56Å; K723-S773 WeakPolarHBondContact O-CA 3.27Å; L762-S773 CarbonylContact C-O 3.55Å; L762-S773 VanDerWaalsContact CA-O 3.27Å; L762-S773 WeakPolarHBondContact CA-O 3.25Å; E763-S773 PolarHBondContact N-O 3.27Å; E763-S773 PolarHBondContact O-N 2.97Å; E763-S773 PolarHBondContact OE1-OG 3.03Å
774Y94.3Very high86.6Confident27 Ų2779.6 Ų79.611%0.10645%0.45CS..EExtended strand (participates in β ladder)trans-93.8126.8178.3-179.7-108.1000110.8V716 M719 K720 K723 Y761 L762 A776V716-Y774 HydrophobicContact CG1-CE2 4.19Å; M719-Y774 HydrophobicContact CB-CD2 3.94Å; M719-Y774 HydrophobicContact CB-CG 4.36Å; M719-Y774 WeakPolarHBondContact O-CB 3.41Å; K720-Y774 HydrophobicContact CB-CD1 4.3Å; K720-Y774 HydrophobicContact CB-CE1 3.78Å; K720-Y774 HydrophobicContact CB-CE2 4.11Å; K720-Y774 HydrophobicContact CD-CE1 4.46Å; K720-Y774 HydrophobicContact CG-CE1 3.76Å; K723-Y774 HydrophobicContact CD-CD1 4.24Å; K723-Y774 PolarHBondContact O-N 3.4Å; Y761-Y774 VanDerWaalsContact O-CD2 3.27Å; Y761-Y774 WeakPolarHBondContact O-CD2 2.83Å; L762-Y774 HydrophobicContact CD2-CD2 4.1Å; Y774-A776 WeakPolarHBondContact CD1-O 3.42Å; Y774-A776 HydrophobicContact CE1-CB 4.26Å; Y774-A776 WeakPolarHBondContact CE1-O 3.33Å; Y774-A776 HydrophobicContact CE2-CB 4.29Å; Y774-A776 WeakPolarHBondContact OH-CB 3.41Å
775L86.6Confident86.1Confident81 Ų8176.6 Ų76.642%0.42445%0.451SS..  trans-95.4-17.7-168.8-77.7177.2000115.5E760 Y761 E763E760-L775 HydrophobicContact CB-CD1 4.47Å; E760-L775 WeakPolarHBondContact O-CB 3.46Å; Y761-L775 PolarHBondContact O-N 2.93Å; Y761-L775 VanDerWaalsContact O-N 3.13Å; E763-L775 HydrophobicContact CB-CD1 3.92Å; E763-L775 HydrophobicContact CB-CD2 4.24Å; E763-L775 HydrophobicContact CB-CG 4.07Å; E763-L775 HydrophobicContact CG-CD1 4.4Å; E763-L775 HydrophobicContact CG-CD2 3.85Å; E763-L775 HydrophobicContact CG-CG 3.99Å; E763-L775 WeakPolarHBondContact OE2-CD2 3.39Å
776A70.9Confident85.8Confident95 Ų9579.3 Ų79.379%0.78547%0.466SS*.  trans-106.50-166.900000116.4Y761 Y774Y761-A776 HydrophobicContact CD1-CB 4.44Å; Y774-A776 WeakPolarHBondContact CD1-O 3.42Å; Y774-A776 HydrophobicContact CE1-CB 4.26Å; Y774-A776 WeakPolarHBondContact CE1-O 3.33Å; Y774-A776 HydrophobicContact CE2-CB 4.29Å; Y774-A776 WeakPolarHBondContact OH-CB 3.41Å

Retrieved 776 of 776 residues in 1453.3 ms (Link to these results)