A0A087XFE7_POEFO Loading...

Sodium/hydrogen exchanger

AlphaFold DB , UniProt , Accession A0A087XFE7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 747 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	32.8	Very low	30.4	Very low	173 Å²	173	142.9 Å²	142.9	100%	1.21	78%	0.783	S	S	*	*				0	143.6	0	-170	0	0	0	0	108.2
2	A	30.1	Very low	30.1	Very low	91 Å²	91	147 Å²	147	75%	0.752	80%	0.797	S	S	*	*			trans	38.8	145.4	159.4	0	0	0	0	0	122.5
3	A	30.7	Very low	30	Very low	90 Å²	90	142.6 Å²	142.6	74%	0.744	79%	0.793	S	S	*	*			trans	-1.1	153.4	143.2	0	0	0	0	0	119
4	D	31.6	Very low	30.2	Very low	119 Å²	119	142.6 Å²	142.6	64%	0.636	80%	0.798	S	S	*	*			cis	-166.7	159.1	48.8	-151.8	-1.8	0	0	0	115.3
5	R	32.1	Very low	30.1	Very low	195 Å²	195	144.4 Å²	144.4	74%	0.736	80%	0.804	S	S	*	*			trans	52.9	134.4	149.7	-91	163.4	-129.3	-127.3	-3	126
6	N	30.2	Very low	30	Very low	131 Å²	131	138.8 Å²	138.8	70%	0.701	79%	0.788	S	S	*	*			trans	79.1	137.7	141.6	-70.6	-13	0	0	0	119.6
7	R	31	Very low	30.3	Very low	196 Å²	196	138.9 Å²	138.9	74%	0.74	80%	0.796	S	S	*	*			cis	166.7	115.7	-24	-116.6	-169.8	-175	-149.6	4.5	104
8	I	28.8	Very low	30.2	Very low	173 Å²	173	134.7 Å²	134.7	89%	0.887	79%	0.788	S	S	*	*			trans	-136.6	124	157.1	-59.2	-177.5	0	0	0	106.5
9	H	29.4	Very low	30.5	Very low	128 Å²	128	133.5 Å²	133.5	59%	0.593	79%	0.785	S	S	*	*			trans	-89	158.6	174.4	-81.4	-82	0	0	0	110.1
10	P	31.9	Very low	30.9	Very low	124 Å²	124	132.6 Å²	132.6	81%	0.805	79%	0.793	S	S	*	*				-132.5	158.4	103.3	32	-20	0	0	0	114.9
11	N	25.6	Very low	31.2	Very low	152 Å²	152	130.9 Å²	130.9	81%	0.813	79%	0.787	S	S	*	*			trans	-47.7	132.6	-173.1	-59.4	-35.4	0	0	0	116.3
12	M	27.3	Very low	31.4	Very low	192 Å²	192	131 Å²	131	95%	0.946	77%	0.767	S	S	*	*			trans	-118.6	97	157	-163.6	176	-172.6	0	0	107.6
13	A	28.8	Very low	32.1	Very low	90 Å²	90	136.8 Å²	136.8	74%	0.744	77%	0.769	S	S	*	*			trans	-89	122.3	-177.2	0	0	0	0	0	110.8
14	V	32.8	Very low	32.5	Very low	143 Å²	143	139 Å²	139	87%	0.867	76%	0.762	S	S	*	*			trans	-71.8	127.7	175.8	175.5	0	0	0	0	109.8
15	L	28.5	Very low	32.9	Very low	169 Å²	169	135.8 Å²	135.8	89%	0.885	76%	0.757	S	S	*	*			trans	-114.5	114	169.2	-104.4	148.2	0	0	0	109.1
16	G	28.6	Very low	33.3	Very low	54 Å²	54	129 Å²	129	56%	0.557	74%	0.739	S	S	*	*			trans	-75.2	174.6	176.2	0	0	0	0	0	113.2	G18	G16-G18 PolarHBondContact O-N 3.47Å; G16-G18 VanDerWaalsContact O-N 3.13Å
17	P	35.6	Very low	34.2	Very low	142 Å²	142	126 Å²	126	92%	0.922	73%	0.725	S	S	*	*			trans	-73.5	105.8	-173.9	29.5	-34.1	0	0	0	112.1
18	G	28.2	Very low	34.9	Very low	63 Å²	63	120.8 Å²	120.8	65%	0.649	71%	0.712	S	S	*	*			trans	-74	159.3	167.7	0	0	0	0	0	112.9	G16	G16-G18 PolarHBondContact O-N 3.47Å; G16-G18 VanDerWaalsContact O-N 3.13Å
19	P	35.9	Very low	35.4	Very low	111 Å²	111	117.3 Å²	117.3	72%	0.721	70%	0.695	S	S	*	*			trans	-73.2	142.7	-167.6	29.3	-35.5	0	0	0	113.8	S21	P19-S21 PolarHBondContact O-N 3.18Å
20	A	37.5	Very low	36.1	Very low	115 Å²	115	116 Å²	116	95%	0.95	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.6	37.7	-178.9	0	0	0	0	0	114.6
21	S	37.4	Very low	36.9	Very low	97 Å²	97	111.9 Å²	111.9	68%	0.678	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.1	-8.1	173.7	45.7	0	0	0	0	113.4	P19 R23	P19-S21 PolarHBondContact O-N 3.18Å; S21-R23 PolarHBondContact O-N 3.3Å
22	F	37.2	Very low	37.9	Very low	177 Å²	177	109.9 Å²	109.9	78%	0.776	65%	0.651	S	S	*	*	S	Bend	trans	-102.7	48.5	-166.9	-141.2	-84	0	0	0	114.7
23	R	44.5	Very low	38.6	Very low	212 Å²	212	105.8 Å²	105.8	80%	0.8	63%	0.632	S	S	*	*	S	Bend	trans	-141.2	-21.9	170.8	-71.2	-163.8	178.2	-176.4	-0.3	117.3	S21 S26 V27	S21-R23 PolarHBondContact O-N 3.3Å; R23-S26 PolarHBondContact O-N 2.94Å; R23-V27 PolarHBondContact O-N 3.3Å
24	F	39.9	Very low	39.2	Very low	136 Å²	136	106.5 Å²	106.5	60%	0.596	62%	0.622	S	S	*	*	H	α-helix	trans	-67.1	-45.5	178.4	-107.3	-91.7	0	0	0	112.7	S26 V27 L28 M101	F24-S26 PolarHBondContact O-N 3.19Å; F24-V27 PolarHBondContact O-N 3.11Å; F24-L28 PolarHBondContact O-N 3.26Å; F24-L28 VanDerWaalsContact O-N 3.12Å; F24-M101 HydrophobicContact CE1-CE 3.81Å; F24-M101 HydrophobicContact CE1-SD 4.3Å; F24-M101 HydrophobicContact CZ-CE 3.64Å; F24-M101 HydrophobicContact CZ-SD 4.17Å
25	G	39	Very low	39.5	Very low	51 Å²	51	102.3 Å²	102.3	53%	0.526	60%	0.599	S	S	.	*	H	α-helix	trans	-60.8	-32.5	178.1	0	0	0	0	0	113.1	L28 L29	G25-L28 PolarHBondContact O-N 3.37Å; G25-L29 VanDerWaalsContact O-CB 3.25Å; G25-L29 WeakPolarHBondContact O-CB 3.12Å; G25-L29 PolarHBondContact O-N 3.21Å
26	S	41.2	Very low	39.7	Very low	53 Å²	53	96.5 Å²	96.5	37%	0.371	58%	0.58	S	S	.	*	H	α-helix	trans	-69.5	-37	179.2	-47.3	0	0	0	0	112.9	R23 F24 L29 I30	R23-S26 PolarHBondContact O-N 2.94Å; F24-S26 PolarHBondContact O-N 3.19Å; S26-L29 PolarHBondContact O-N 3.32Å; S26-I30 WeakPolarHBondContact O-CD1 3.42Å; S26-I30 VanDerWaalsContact O-CG1 3.28Å; S26-I30 WeakPolarHBondContact O-CG1 3.4Å; S26-I30 PolarHBondContact O-N 3.5Å
27	V	49.8	Very low	39.9	Very low	67 Å²	67	97.8 Å²	97.8	41%	0.406	58%	0.581	S	S	.	*	H	α-helix	trans	-72.6	-40	175.4	179.2	0	0	0	0	110.6	R23 F24 L29 I30 L31 L97	R23-V27 PolarHBondContact O-N 3.3Å; F24-V27 PolarHBondContact O-N 3.11Å; V27-L29 VanDerWaalsContact C-N 3.29Å; V27-L29 PolarHBondContact O-N 3.15Å; V27-I30 PolarHBondContact O-N 2.63Å; V27-L31 HydrophobicContact CG1-CD1 4.42Å; V27-L31 PolarHBondContact O-N 3.45Å; V27-L97 HydrophobicContact CG1-CD1 4.19Å
28	L	44.8	Very low	39.9	Very low	88 Å²	88	95.9 Å²	95.9	46%	0.461	57%	0.57	S	S	.	*	H	α-helix	trans	-62.5	-37.4	172.3	-165.5	75.2	0	0	0	111.8	F24 G25 L31 L32	F24-L28 PolarHBondContact O-N 3.26Å; F24-L28 VanDerWaalsContact O-N 3.12Å; G25-L28 PolarHBondContact O-N 3.37Å; L28-L31 PolarHBondContact O-N 2.87Å; L28-L32 HydrophobicContact CG-CD1 4.37Å; L28-L32 WeakPolarHBondContact O-CB 3.29Å; L28-L32 WeakPolarHBondContact O-CG 3.33Å; L28-L32 PolarHBondContact O-N 3.06Å
29	L	39	Very low	40	Very low	100 Å²	100	104 Å²	104	52%	0.524	58%	0.581	S	S	.	*	H	α-helix	trans	-67.2	-39.3	174.9	-163.9	79.1	0	0	0	111.6	G25 S26 V27 L32 I33	G25-L29 VanDerWaalsContact O-CB 3.25Å; G25-L29 WeakPolarHBondContact O-CB 3.12Å; G25-L29 PolarHBondContact O-N 3.21Å; S26-L29 PolarHBondContact O-N 3.32Å; V27-L29 VanDerWaalsContact C-N 3.29Å; V27-L29 PolarHBondContact O-N 3.15Å; L29-L32 PolarHBondContact O-N 3.13Å; L29-I33 HydrophobicContact CD2-CD1 4.15Å; L29-I33 HydrophobicContact CG-CD1 3.87Å; L29-I33 HydrophobicContact CG-CG1 4.48Å; L29-I33 WeakPolarHBondContact O-CB 3.18Å; L29-I33 WeakPolarHBondContact O-CD1 3.11Å; L29-I33 WeakPolarHBondContact O-CG1 3.23Å; L29-I33 PolarHBondContact O-N 2.99Å
30	I	45.7	Very low	39.8	Very low	100 Å²	100	104.7 Å²	104.7	51%	0.513	58%	0.584	S	S	.	*	H	α-helix	trans	-64.8	-41.2	174.5	-71.6	162.9	0	0	0	110.9	S26 V27 I33 L34	S26-I30 WeakPolarHBondContact O-CD1 3.42Å; S26-I30 VanDerWaalsContact O-CG1 3.28Å; S26-I30 WeakPolarHBondContact O-CG1 3.4Å; S26-I30 PolarHBondContact O-N 3.5Å; V27-I30 PolarHBondContact O-N 2.63Å; I30-I33 PolarHBondContact O-N 3.35Å; I30-L34 HydrophobicContact CG2-CD1 3.94Å; I30-L34 WeakPolarHBondContact O-CB 3.43Å; I30-L34 PolarHBondContact O-N 3.05Å
31	L	47.7	Very low	39.4	Very low	38 Å²	38	110.4 Å²	110.4	20%	0.199	58%	0.581	C	S	.	*	H	α-helix	trans	-59.9	-47.9	171.5	-79.5	158.9	0	0	0	111.5	V27 L28 I33 L34 S35 L97	V27-L31 HydrophobicContact CG1-CD1 4.42Å; V27-L31 PolarHBondContact O-N 3.45Å; L28-L31 PolarHBondContact O-N 2.87Å; L31-I33 VanDerWaalsContact C-N 3.34Å; L31-I33 PolarHBondContact O-N 3.11Å; L31-L34 PolarHBondContact O-N 3.41Å; L31-S35 PolarHBondContact O-N 3.24Å; L31-S35 PolarHBondContact O-OG 3.39Å; L31-L97 HydrophobicContact CD1-CD2 4.22Å; L31-L97 HydrophobicContact CD2-CD2 4.47Å
32	L	46.3	Very low	39	Very low	109 Å²	109	114 Å²	114	57%	0.571	59%	0.592	S	S	*	*	H	α-helix	trans	-65.2	-32.7	177.4	-75.5	166.6	0	0	0	113.4	L28 L29 G36	L28-L32 HydrophobicContact CG-CD1 4.37Å; L28-L32 WeakPolarHBondContact O-CB 3.29Å; L28-L32 WeakPolarHBondContact O-CG 3.33Å; L28-L32 PolarHBondContact O-N 3.06Å; L29-L32 PolarHBondContact O-N 3.13Å; L32-G36 WeakPolarHBondContact O-CA 3.48Å; L32-G36 PolarHBondContact O-N 3.21Å
33	I	41.8	Very low	38.6	Very low	107 Å²	107	110.9 Å²	110.9	55%	0.549	59%	0.588	S	S	.	*	H	α-helix	trans	-73.1	-39.6	176.7	-72.3	164.9	0	0	0	110.7	L29 I30 L31 G36 S37	L29-I33 HydrophobicContact CD2-CD1 4.15Å; L29-I33 HydrophobicContact CG-CD1 3.87Å; L29-I33 HydrophobicContact CG-CG1 4.48Å; L29-I33 WeakPolarHBondContact O-CB 3.18Å; L29-I33 WeakPolarHBondContact O-CD1 3.11Å; L29-I33 WeakPolarHBondContact O-CG1 3.23Å; L29-I33 PolarHBondContact O-N 2.99Å; I30-I33 PolarHBondContact O-N 3.35Å; L31-I33 VanDerWaalsContact C-N 3.34Å; L31-I33 PolarHBondContact O-N 3.11Å; I33-G36 PolarHBondContact O-N 3.32Å; I33-S37 PolarHBondContact O-N 3.35Å; I33-S37 VanDerWaalsContact O-N 3.09Å; I33-S37 PolarHBondContact O-OG 3.23Å
34	L	42.2	Very low	38.2	Very low	105 Å²	105	106.9 Å²	106.9	55%	0.55	59%	0.589	S	S	.	*	H	α-helix	trans	-69.7	-38.6	175.3	-80.1	160	0	0	0	112.6	I30 L31 S37	I30-L34 HydrophobicContact CG2-CD1 3.94Å; I30-L34 WeakPolarHBondContact O-CB 3.43Å; I30-L34 PolarHBondContact O-N 3.05Å; L31-L34 PolarHBondContact O-N 3.41Å; L34-S37 PolarHBondContact O-OG 3.41Å
35	S	39	Very low	37.7	Very low	55 Å²	55	106.8 Å²	106.8	39%	0.385	60%	0.6	S	S	.	*	H	α-helix	trans	-71.4	-30.1	170.7	-59.9	0	0	0	0	112.7	L31	L31-S35 PolarHBondContact O-N 3.24Å; L31-S35 PolarHBondContact O-OG 3.39Å
36	G	32	Very low	37.2	Very low	46 Å²	46	108.1 Å²	108.1	47%	0.474	61%	0.614	S	S	.	*	H	α-helix	trans	-74	-24.9	179.3	0	0	0	0	0	114.4	L32 I33 S38 W39	L32-G36 WeakPolarHBondContact O-CA 3.48Å; L32-G36 PolarHBondContact O-N 3.21Å; I33-G36 PolarHBondContact O-N 3.32Å; G36-S38 PolarHBondContact O-N 3.04Å; G36-S38 VanDerWaalsContact O-N 3.12Å; G36-W39 PolarHBondContact O-N 3.31Å
37	S	33.5	Very low	36.6	Very low	82 Å²	82	116.4 Å²	116.4	57%	0.573	64%	0.637	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.7	-10.6	175.3	31.2	0	0	0	0	114.8	I33 L34 W39	I33-S37 PolarHBondContact O-N 3.35Å; I33-S37 VanDerWaalsContact O-N 3.09Å; I33-S37 PolarHBondContact O-OG 3.23Å; L34-S37 PolarHBondContact O-OG 3.41Å; S37-W39 PolarHBondContact O-N 2.81Å
38	S	35.2	Very low	35.6	Very low	101 Å²	101	119.4 Å²	119.4	71%	0.706	65%	0.651	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72	-3.3	173.3	-57.3	0	0	0	0	114.2	G36	G36-S38 PolarHBondContact O-N 3.04Å; G36-S38 VanDerWaalsContact O-N 3.12Å
39	W	31.2	Very low	34.9	Very low	233 Å²	233	123 Å²	123	88%	0.883	67%	0.671	S	S	*	*			trans	-114.5	63.5	-179	-93.1	59.4	0	0	0	113.2	G36 S37	G36-W39 PolarHBondContact O-N 3.31Å; S37-W39 PolarHBondContact O-N 2.81Å
40	T	31.9	Very low	34.5	Very low	126 Å²	126	124.4 Å²	124.4	77%	0.773	68%	0.683	S	S	*	*			trans	-163.9	104.4	148.8	38.5	0	0	0	0	112.7
41	R	27.9	Very low	33.7	Very low	236 Å²	236	131.3 Å²	131.3	89%	0.891	70%	0.703	S	S	*	*			trans	154.5	91.2	131.9	-87.4	174.7	171.3	169.4	-1.1	111.7	V43	R41-V43 PolarHBondContact O-N 2.78Å
42	D	29	Very low	33.2	Very low	171 Å²	171	135.1 Å²	135.1	91%	0.914	73%	0.73	S	S	*	*			trans	-67.2	124.9	156.4	-70.9	-56.3	0	0	0	109.9
43	V	29.2	Very low	32.4	Very low	113 Å²	113	139.1 Å²	139.1	69%	0.685	75%	0.746	S	S	*	*			trans	-132.1	120.4	162	178.4	0	0	0	0	106.7	R41 T45	R41-V43 PolarHBondContact O-N 2.78Å; V43-T45 PolarHBondContact O-N 3.37Å
44	P	35.6	Very low	31.9	Very low	128 Å²	128	142 Å²	142	83%	0.831	76%	0.761	S	S	*	*			trans	-82	120.1	-172.3	31.3	-33.5	0	0	0	111.3
45	T	30.1	Very low	31.4	Very low	134 Å²	134	144 Å²	144	82%	0.822	77%	0.773	S	S	*	*			trans	-127.3	121.3	165.7	47.3	0	0	0	0	109.7	V43	V43-T45 PolarHBondContact O-N 3.37Å
46	G	27.4	Very low	30.9	Very low	79 Å²	79	151.1 Å²	151.1	81%	0.814	79%	0.791	S	S	*	*			trans	-77.5	129.5	-171.7	0	0	0	0	0	114.2
47	R	29	Very low	30.8	Very low	227 Å²	227	156.1 Å²	156.1	86%	0.857	80%	0.802	S	S	*	*				40.1	94.9	120.1	-174.3	170.3	-166.8	166.6	7.9	117.7
48	N	29.7	Very low	30.6	Very low	129 Å²	129	162.7 Å²	162.7	69%	0.69	81%	0.814	S	S	*	*				163.9	133	115.5	-89.9	-16.2	0	0	0	110.2
49	D	28.8	Very low	30.3	Very low	165 Å²	165	165.2 Å²	165.2	88%	0.882	82%	0.82	S	S	*	*				-175.8	95.8	123.2	-97.4	-9.1	0	0	0	111.5
50	T	31.4	Very low	30.2	Very low	128 Å²	128	157.6 Å²	157.6	79%	0.785	81%	0.814	S	S	*	*			trans	-77.7	120.9	154.5	38.5	0	0	0	0	108.9	P52	T50-P52 WeakPolarHBondContact O-CD 3.37Å
51	R	28	Very low	30.1	Very low	245 Å²	245	160 Å²	160	93%	0.925	82%	0.816	S	S	*	*			trans	-65.2	138.9	162.3	-91.9	-179.9	164.2	177.7	-5.1	110.7
52	P	37.5	Very low	30.2	Very low	119 Å²	119	154.6 Å²	154.6	77%	0.773	81%	0.805	S	S	*	*			trans	-118.9	-173.5	140.5	37.3	-29.3	0	0	0	111.4	T50	T50-P52 WeakPolarHBondContact O-CD 3.37Å
53	E	30.8	Very low	30.4	Very low	192 Å²	192	157.2 Å²	157.2	90%	0.897	80%	0.802	S	S	*	*			trans	-90.5	172.2	-153.6	-61.9	165	120.8	0	0	115.6	N55	E53-N55 PolarHBondContact O-N 2.85Å
54	L	31.6	Very low	30.5	Very low	167 Å²	167	159.9 Å²	159.9	87%	0.874	81%	0.812	S	S	*	*			trans	-57.8	125.5	169.1	-116.6	74.9	0	0	0	111.5
55	N	29.7	Very low	30.4	Very low	148 Å²	148	162.8 Å²	162.8	79%	0.791	81%	0.814	S	S	*	*			trans	-162.3	134.7	139.5	-107.1	-41.6	0	0	0	114.3	E53	E53-N55 PolarHBondContact O-N 2.85Å
56	R	29.1	Very low	30.4	Very low	205 Å²	205	160 Å²	160	77%	0.774	81%	0.813	S	S	*	*			trans	35.6	137.4	147.1	-94.2	-177.5	153.9	105	-1.1	123.8
57	E	29.5	Very low	30.8	Very low	151 Å²	151	163.6 Å²	163.6	71%	0.706	81%	0.813	S	S	*	*			trans	96.1	109.1	135.4	-77.6	164.9	-168.7	0	0	122
58	R	30.9	Very low	31	Very low	220 Å²	220	160.5 Å²	160.5	83%	0.83	81%	0.814	S	S	*	*			trans	50.7	144.2	133.4	-75.2	-167.7	-175.6	-174.9	2.9	124.2
59	D	28.8	Very low	31.6	Very low	153 Å²	153	158.3 Å²	158.3	82%	0.818	81%	0.814	S	S	*	*			trans	75.8	149.8	153.3	-59.8	-17.3	0	0	0	119.9
60	G	28.9	Very low	32.4	Very low	73 Å²	73	156.9 Å²	156.9	75%	0.753	81%	0.811	S	S	*	*			trans	110.3	55.4	152.4	0	0	0	0	0	120.3
61	Q	29.4	Very low	33	Very low	176 Å²	176	159.9 Å²	159.9	82%	0.822	81%	0.813	S	S	*	*				42.2	138.4	125.3	-164.7	164	8.9	0	0	122.9
62	N	29.5	Very low	33.7	Very low	124 Å²	124	156.6 Å²	156.6	66%	0.663	81%	0.808	S	S	*	*			trans	84.7	104.7	160.3	-75.4	-11.8	0	0	0	121.4
63	R	32.9	Very low	33.9	Very low	226 Å²	226	160.2 Å²	160.2	85%	0.853	81%	0.811	S	S	*	*				30.5	123.8	118.5	-63.1	178.5	177.1	176.2	-0.5	118.3
64	D	31.1	Very low	34.9	Very low	168 Å²	168	155 Å²	155	90%	0.898	80%	0.801	S	S	*	*				-152.3	157.5	102.6	-120.4	-25.9	0	0	0	114.1
65	H	34.6	Very low	36.1	Very low	189 Å²	189	155.7 Å²	155.7	88%	0.875	80%	0.797	S	S	*	*			trans	-87.2	141	-178.9	-91.3	-64.1	0	0	0	112.5
66	G	30	Very low	37.6	Very low	76 Å²	76	152.3 Å²	152.3	78%	0.784	78%	0.783	S	S	*	*			trans	-161.5	81.9	171.6	0	0	0	0	0	112.5	N68	G66-N68 PolarHBondContact O-N 2.82Å
67	N	35.3	Very low	39.3	Very low	154 Å²	154	149.3 Å²	149.3	82%	0.824	79%	0.787	S	S	*	*			trans	-55.9	132.9	174	-82.2	-21.5	0	0	0	111.2
68	N	34	Very low	40.5	Very low	163 Å²	163	149.3 Å²	149.3	87%	0.872	79%	0.791	S	S	*	*			trans	-157.1	114.5	139.2	-103.8	-34.8	0	0	0	113.8	G66	G66-N68 PolarHBondContact O-N 2.82Å
69	A	41	Very low	42.3	Very low	83 Å²	83	144.8 Å²	144.8	69%	0.686	78%	0.78	S	S	*	*			trans	36	100.6	152.4	0	0	0	0	0	118.5	K71	A69-K71 PolarHBondContact O-N 2.86Å
70	T	46	Very low	44.2	Very low	134 Å²	134	145 Å²	145	82%	0.822	78%	0.78	S	S	*	*			trans	-60.4	75.5	155.4	39.4	0	0	0	0	111.9	H72	T70-H72 PolarHBondContact O-N 2.67Å
71	K	44.6	Very low	46.5	Very low	191 Å²	191	146.3 Å²	146.3	83%	0.83	77%	0.77	S	S	*	*			trans	-74.8	73.1	158.4	-85.5	-172.3	175.3	177.4	0	109.4	A69 K73	A69-K71 PolarHBondContact O-N 2.86Å; K71-K73 VanDerWaalsContact C-N 3.35Å; K71-K73 PolarHBondContact O-N 3.47Å
72	H	41.9	Very low	48.8	Very low	176 Å²	176	143.3 Å²	143.3	82%	0.815	75%	0.751	S	S	*	*			trans	-53.3	105.9	150.2	-97.9	-89.9	0	0	0	106.8	T70 A74	T70-H72 PolarHBondContact O-N 2.67Å; H72-A74 PolarHBondContact O-N 3.21Å; H72-A74 VanDerWaalsContact O-N 3.08Å
73	K	42.8	Very low	51	Low	196 Å²	196	144.2 Å²	144.2	85%	0.852	76%	0.757	S	S	*	*			trans	-66.7	108.3	162.3	-80.4	-175.7	176.2	178.4	0	106	K71 F75	K71-K73 VanDerWaalsContact C-N 3.35Å; K71-K73 PolarHBondContact O-N 3.47Å; K73-F75 PolarHBondContact O-N 2.83Å
74	A	50.9	Low	53.2	Low	81 Å²	81	143.1 Å²	143.1	67%	0.669	75%	0.754	S	S	*	*			trans	-56.3	134.1	171.7	0	0	0	0	0	109	H72	H72-A74 PolarHBondContact O-N 3.21Å; H72-A74 VanDerWaalsContact O-N 3.08Å
75	F	57.3	Low	55.7	Low	183 Å²	183	138.3 Å²	138.3	80%	0.803	73%	0.73	S	S	*	*			trans	17.2	101.9	170	-55.8	-78.7	0	0	0	115.9	K73 V77	K73-F75 PolarHBondContact O-N 2.83Å; F75-V77 WeakPolarHBondContact O-CG2 3.38Å; F75-V77 PolarHBondContact O-N 3.45Å
76	P	61.2	Low	57.7	Low	77 Å²	77	133.1 Å²	133.1	50%	0.5	70%	0.703	S	S	.	*			trans	-61.3	103.4	173.8	25.9	-33.1	0	0	0	109.6	L78 E79	P76-L78 PolarHBondContact O-N 3.14Å; P76-E79 HydrophobicContact CB-CB 4.43Å; P76-E79 HydrophobicContact CB-CG 3.81Å; P76-E79 WeakPolarHBondContact CB-OE1 3.34Å; P76-E79 HydrophobicContact CG-CG 4.13Å; P76-E79 VanDerWaalsContact CG-OE1 3.29Å; P76-E79 WeakPolarHBondContact CG-OE1 3.07Å
77	V	65.3	Low	59.6	Low	141 Å²	141	135.3 Å²	135.3	86%	0.855	69%	0.694	S	S	*	*	S	Bend	trans	-66.8	-22.1	-174.2	-175.4	0	0	0	0	112	F75	F75-V77 WeakPolarHBondContact O-CG2 3.38Å; F75-V77 PolarHBondContact O-N 3.45Å
78	L	54.8	Low	61.6	Low	151 Å²	151	131.3 Å²	131.3	79%	0.791	68%	0.676	S	S	*	*			trans	-143.3	113.2	166.4	-116.3	102	0	0	0	109.4	P76	P76-L78 PolarHBondContact O-N 3.14Å
79	E	69.1	Low	63.6	Low	126 Å²	126	128.8 Å²	128.8	59%	0.589	66%	0.658	S	S	*	*			trans	-111.7	118.2	167.4	-110.6	168.8	-165.4	0	0	109	P76 N81	P76-E79 HydrophobicContact CB-CB 4.43Å; P76-E79 HydrophobicContact CB-CG 3.81Å; P76-E79 WeakPolarHBondContact CB-OE1 3.34Å; P76-E79 HydrophobicContact CG-CG 4.13Å; P76-E79 VanDerWaalsContact CG-OE1 3.29Å; P76-E79 WeakPolarHBondContact CG-OE1 3.07Å; E79-N81 VanDerWaalsContact C-N 3.31Å; E79-N81 PolarHBondContact O-N 2.79Å
80	L	68.5	Low	65.1	Low	156 Å²	156	127 Å²	127	82%	0.817	64%	0.635	S	S	*	*			trans	-82.3	76.8	-179.4	-72.4	173.1	0	0	0	110.2	Y82	L80-Y82 PolarHBondContact O-N 2.91Å
81	N	77.8	Confident	66.3	Low	102 Å²	102	123.9 Å²	123.9	55%	0.545	61%	0.613	S	S	.	*			trans	-75.2	57.7	177.2	-68.5	-31	0	0	0	111.9	E79 D83 Y84	E79-N81 VanDerWaalsContact C-N 3.31Å; E79-N81 PolarHBondContact O-N 2.79Å; N81-D83 VanDerWaalsContact C-N 3.35Å; N81-D83 PolarHBondContact O-N 3.09Å; N81-Y84 PolarHBondContact O-N 3.24Å
82	Y	76.3	Confident	67.8	Low	112 Å²	112	118.3 Å²	118.3	44%	0.439	60%	0.598	S	S	.	*	H	α-helix	trans	-59.3	-44.4	-179.8	-176.5	-103.7	0	0	0	111.5	L80 Y84 V85 R86 F89 E90	L80-Y82 PolarHBondContact O-N 2.91Å; Y82-Y84 PolarHBondContact O-N 3.08Å; Y82-Y84 VanDerWaalsContact O-N 3.13Å; Y82-V85 CarbonylContact O-C 3.55Å; Y82-V85 PolarHBondContact O-N 3.39Å; Y82-R86 HydrophobicContact CD1-CB 4.31Å; Y82-R86 HydrophobicContact CD1-CG 4.37Å; Y82-R86 HydrophobicContact CE1-CB 4Å; Y82-R86 HydrophobicContact CE1-CG 3.63Å; Y82-R86 WeakPolarHBondContact O-CA 3.37Å; Y82-R86 WeakPolarHBondContact O-CB 3.38Å; Y82-R86 PolarHBondContact O-N 3.35Å; Y82-F89 HydrophobicContact CE2-CD1 4.21Å; Y82-E90 PolarHBondContact OH-OE1 3.08Å
83	D	76.9	Confident	69.4	Low	144 Å²	144	113 Å²	113	77%	0.77	58%	0.575	S	S	*	*	H	α-helix	trans	-58.7	-30.2	-177.1	-59.9	-53	0	0	0	113.7	N81	N81-D83 VanDerWaalsContact C-N 3.35Å; N81-D83 PolarHBondContact O-N 3.09Å
84	Y	78.9	Confident	70.8	Confident	203 Å²	203	105.8 Å²	105.8	80%	0.796	54%	0.543	S	S	*	.	H	α-helix	trans	-73.1	-35.1	176.4	-179.7	-107.1	0	0	0	112.8	N81 Y82	N81-Y84 PolarHBondContact O-N 3.24Å; Y82-Y84 PolarHBondContact O-N 3.08Å; Y82-Y84 VanDerWaalsContact O-N 3.13Å
85	V	83.4	Confident	71.9	Confident	66 Å²	66	104.5 Å²	104.5	40%	0.4	52%	0.524	S	S	.	.	H	α-helix	trans	-103.3	-4.2	-174.8	-158.3	0	0	0	0	112.1	Y82 M87 P88 F89	Y82-V85 CarbonylContact O-C 3.55Å; Y82-V85 PolarHBondContact O-N 3.39Å; V85-M87 PolarHBondContact O-N 3.04Å; V85-P88 HydrophobicContact CG1-CG 4.14Å; V85-P88 WeakPolarHBondContact O-CD 3.43Å; V85-P88 VanDerWaalsContact O-CG 3.28Å; V85-P88 WeakPolarHBondContact O-CG 3.42Å; V85-F89 HydrophobicContact CG1-CB 4.28Å; V85-F89 WeakPolarHBondContact O-CB 3.35Å; V85-F89 PolarHBondContact O-N 2.88Å
86	R	77	Confident	72.9	Confident	81 Å²	81	100.5 Å²	100.5	31%	0.306	51%	0.51	S	S	.	.	H	α-helix	trans	-47.7	-59.8	-172.6	-177.8	172	-175.3	-158.6	-11	113	Y82 F89 E90 E137	Y82-R86 HydrophobicContact CD1-CB 4.31Å; Y82-R86 HydrophobicContact CD1-CG 4.37Å; Y82-R86 HydrophobicContact CE1-CB 4Å; Y82-R86 HydrophobicContact CE1-CG 3.63Å; Y82-R86 WeakPolarHBondContact O-CA 3.37Å; Y82-R86 WeakPolarHBondContact O-CB 3.38Å; Y82-R86 PolarHBondContact O-N 3.35Å; R86-F89 PolarHBondContact O-N 2.79Å; R86-E90 WeakPolarHBondContact CG-OE1 3.45Å; R86-E90 IonicContact CZ-OE1 3.82Å; R86-E90 IonicContact NE-OE1 2.69Å; R86-E90 PolarHBondContact NE-OE1 2.96Å; R86-E90 IonicContact NH2-OE1 3.18Å; R86-E90 PolarHBondContact NH2-OE1 3.42Å; R86-E90 WeakPolarHBondContact O-CB 3.48Å; R86-E90 WeakPolarHBondContact O-CG 3.45Å; R86-E90 PolarHBondContact O-N 2.89Å; R86-E137 IonicContact CZ-OE1 2.84Å; R86-E137 IonicContact NH1-OE1 3.32Å; R86-E137 PolarHBondContact NH1-OE1 3.41Å; R86-E137 IonicContact NH2-OE1 2.65Å; R86-E137 PolarHBondContact NH2-OE1 3.25Å; R86-E137 IonicContact NH2-OE2 3.19Å; R86-E137 PolarHBondContact NH2-OE2 2.99Å
87	M	68.6	Low	73.5	Confident	122 Å²	122	98 Å²	98	60%	0.601	49%	0.493	S	S	*	.	H	α-helix	trans	-60	-54	-177.9	-61.3	-67.5	-82.4	0	0	113.3	V85 F89 I91	V85-M87 PolarHBondContact O-N 3.04Å; M87-F89 VanDerWaalsContact C-N 3.31Å; M87-F89 PolarHBondContact O-N 3.24Å; M87-I91 WeakPolarHBondContact O-CB 3.44Å; M87-I91 WeakPolarHBondContact O-CD1 3.46Å; M87-I91 VanDerWaalsContact O-CG1 3.27Å; M87-I91 WeakPolarHBondContact O-CG1 3.36Å; M87-I91 PolarHBondContact O-N 2.78Å
88	P	76.7	Confident	73.9	Confident	69 Å²	69	91.3 Å²	91.3	45%	0.448	45%	0.452	S	S	.	.	H	α-helix	trans	-67.2	-28.3	177.8	24.7	-33.5	0	0	0	113.5	V85 S92	V85-P88 HydrophobicContact CG1-CG 4.14Å; V85-P88 WeakPolarHBondContact O-CD 3.43Å; V85-P88 VanDerWaalsContact O-CG 3.28Å; V85-P88 WeakPolarHBondContact O-CG 3.42Å; P88-S92 VanDerWaalsContact O-CB 3.26Å; P88-S92 WeakPolarHBondContact O-CB 3.33Å; P88-S92 PolarHBondContact O-N 2.93Å; P88-S92 PolarHBondContact O-OG 3.18Å
89	F	76.8	Confident	74.9	Confident	110 Å²	110	87.6 Å²	87.6	48%	0.482	43%	0.433	S	S	.	.	H	α-helix	trans	-69.4	-48.1	176.2	-174.4	-98.9	0	0	0	111.7	Y82 V85 R86 M87 S92 L93	Y82-F89 HydrophobicContact CE2-CD1 4.21Å; V85-F89 HydrophobicContact CG1-CB 4.28Å; V85-F89 WeakPolarHBondContact O-CB 3.35Å; V85-F89 PolarHBondContact O-N 2.88Å; R86-F89 PolarHBondContact O-N 2.79Å; M87-F89 VanDerWaalsContact C-N 3.31Å; M87-F89 PolarHBondContact O-N 3.24Å; F89-S92 PolarHBondContact O-N 2.89Å; F89-L93 HydrophobicContact CE1-CD1 4.27Å; F89-L93 WeakPolarHBondContact O-CB 3.41Å; F89-L93 PolarHBondContact O-N 3.1Å
90	E	72.4	Confident	75.4	Confident	45 Å²	45	86.3 Å²	86.3	21%	0.21	43%	0.429	C	S	.	.	H	α-helix	trans	-59.3	-49.9	175.5	-73.2	170.5	-172.1	0	0	110.6	Y82 R86 S92 L93 W94	Y82-E90 PolarHBondContact OH-OE1 3.08Å; R86-E90 WeakPolarHBondContact CG-OE1 3.45Å; R86-E90 IonicContact CZ-OE1 3.82Å; R86-E90 IonicContact NE-OE1 2.69Å; R86-E90 PolarHBondContact NE-OE1 2.96Å; R86-E90 IonicContact NH2-OE1 3.18Å; R86-E90 PolarHBondContact NH2-OE1 3.42Å; R86-E90 WeakPolarHBondContact O-CB 3.48Å; R86-E90 WeakPolarHBondContact O-CG 3.45Å; R86-E90 PolarHBondContact O-N 2.89Å; E90-S92 VanDerWaalsContact C-N 3.33Å; E90-S92 PolarHBondContact O-N 3.06Å; E90-L93 PolarHBondContact O-N 3.05Å; E90-L93 VanDerWaalsContact O-N 3.11Å; E90-W94 VanDerWaalsContact C-CD1 3.46Å; E90-W94 PolarHBondContact O-N 2.93Å
91	I	72	Confident	75.6	Confident	70 Å²	70	80.9 Å²	80.9	36%	0.359	40%	0.4	S	S	.	.	H	α-helix	trans	-55.7	-46.2	175.1	-67.6	167.2	0	0	0	111.4	M87 L93 W94 I95	M87-I91 WeakPolarHBondContact O-CB 3.44Å; M87-I91 WeakPolarHBondContact O-CD1 3.46Å; M87-I91 VanDerWaalsContact O-CG1 3.27Å; M87-I91 WeakPolarHBondContact O-CG1 3.36Å; M87-I91 PolarHBondContact O-N 2.78Å; I91-L93 VanDerWaalsContact C-N 3.31Å; I91-L93 PolarHBondContact O-N 3.11Å; I91-W94 PolarHBondContact O-N 2.96Å; I91-I95 HydrophobicContact CG2-CD1 3.83Å; I91-I95 VanDerWaalsContact O-CG1 3.25Å; I91-I95 WeakPolarHBondContact O-CG1 3.23Å; I91-I95 PolarHBondContact O-N 3.49Å
92	S	74.5	Confident	75.4	Confident	74 Å²	74	77.9 Å²	77.9	52%	0.517	38%	0.383	S	S	.	.	H	α-helix	trans	-63.2	-36.7	178.3	-60.9	0	0	0	0	112.5	P88 F89 E90 L96	P88-S92 VanDerWaalsContact O-CB 3.26Å; P88-S92 WeakPolarHBondContact O-CB 3.33Å; P88-S92 PolarHBondContact O-N 2.93Å; P88-S92 PolarHBondContact O-OG 3.18Å; F89-S92 PolarHBondContact O-N 2.89Å; E90-S92 VanDerWaalsContact C-N 3.33Å; E90-S92 PolarHBondContact O-N 3.06Å; S92-L96 VanDerWaalsContact O-CB 3.31Å; S92-L96 WeakPolarHBondContact O-CB 3.27Å; S92-L96 PolarHBondContact O-N 3.49Å
93	L	76.1	Confident	75.5	Confident	63 Å²	63	77.5 Å²	77.5	33%	0.33	39%	0.387	S	S	.	.	H	α-helix	trans	-69.6	-39.7	177.2	-172.7	148.7	0	0	0	111.8	F89 E90 I91 L96 L97	F89-L93 HydrophobicContact CE1-CD1 4.27Å; F89-L93 WeakPolarHBondContact O-CB 3.41Å; F89-L93 PolarHBondContact O-N 3.1Å; E90-L93 PolarHBondContact O-N 3.05Å; E90-L93 VanDerWaalsContact O-N 3.11Å; I91-L93 VanDerWaalsContact C-N 3.31Å; I91-L93 PolarHBondContact O-N 3.11Å; L93-L96 PolarHBondContact O-N 2.96Å; L93-L97 WeakPolarHBondContact O-CB 3.19Å; L93-L97 PolarHBondContact O-N 2.91Å
94	W	72.1	Confident	75.3	Confident	46 Å²	46	71.9 Å²	71.9	17%	0.174	36%	0.364	C	S	.	.	H	α-helix	trans	-62.1	-43.9	173.2	-64.2	124.2	0	0	0	112.1	E90 I91 L97 A98 I128 V131 I132	E90-W94 VanDerWaalsContact C-CD1 3.46Å; E90-W94 PolarHBondContact O-N 2.93Å; I91-W94 PolarHBondContact O-N 2.96Å; W94-L97 HydrophobicContact CE3-CD2 4.35Å; W94-L97 HydrophobicContact CZ3-CD2 4.49Å; W94-L97 PolarHBondContact O-N 3.03Å; W94-A98 PolarHBondContact O-N 2.92Å; W94-I128 HydrophobicContact CD2-CG2 3.75Å; W94-I128 HydrophobicContact CE3-CB 4.09Å; W94-I128 HydrophobicContact CE3-CD1 3.81Å; W94-I128 HydrophobicContact CE3-CG1 3.58Å; W94-I128 HydrophobicContact CE3-CG2 3.49Å; W94-I128 VanDerWaalsContact CE3-CG2 3.49Å; W94-I128 HydrophobicContact CG-CG2 4.43Å; W94-I128 HydrophobicContact CH2-CG2 4.01Å; W94-I128 HydrophobicContact CZ2-CG2 4.25Å; W94-I128 HydrophobicContact CZ3-CB 4.05Å; W94-I128 HydrophobicContact CZ3-CD1 4.43Å; W94-I128 HydrophobicContact CZ3-CG1 3.7Å; W94-I128 HydrophobicContact CZ3-CG2 3.64Å; W94-V131 HydrophobicContact CH2-CG1 4.37Å; W94-I132 HydrophobicContact CH2-CG1 4.16Å; W94-I132 HydrophobicContact CZ2-CD1 3.91Å; W94-I132 HydrophobicContact CZ2-CG1 3.72Å
95	I	73.9	Confident	74.9	Confident	53 Å²	53	63.1 Å²	63.1	27%	0.272	33%	0.33	S	S	.	.	H	α-helix	trans	-64.2	-45.6	177	-64.3	169.4	0	0	0	110.4	I91 L97 A98 L99 L379	I91-I95 HydrophobicContact CG2-CD1 3.83Å; I91-I95 VanDerWaalsContact O-CG1 3.25Å; I91-I95 WeakPolarHBondContact O-CG1 3.23Å; I91-I95 PolarHBondContact O-N 3.49Å; I95-L97 PolarHBondContact O-N 3.13Å; I95-A98 PolarHBondContact O-N 3.48Å; I95-L99 HydrophobicContact CG2-CD1 4.03Å; I95-L99 HydrophobicContact CG2-CG 4.44Å; I95-L99 WeakPolarHBondContact O-CG 3.48Å; I95-L99 PolarHBondContact O-N 2.94Å; I95-L379 HydrophobicContact CD1-CD2 3.65Å; I95-L379 HydrophobicContact CG1-CD2 3.56Å; I95-L379 HydrophobicContact CG2-CD2 4.48Å
96	L	78.4	Confident	74.4	Confident	99 Å²	99	67.1 Å²	67.1	52%	0.518	34%	0.344	S	S	.	.	H	α-helix	trans	-59	-45.3	176	178.9	62.8	0	0	0	111.6	S92 L93 A98 L99 L100	S92-L96 VanDerWaalsContact O-CB 3.31Å; S92-L96 WeakPolarHBondContact O-CB 3.27Å; S92-L96 PolarHBondContact O-N 3.49Å; L93-L96 PolarHBondContact O-N 2.96Å; L96-A98 VanDerWaalsContact C-N 3.35Å; L96-A98 PolarHBondContact O-N 3.46Å; L96-L99 PolarHBondContact O-N 3.06Å; L96-L100 HydrophobicContact CD1-CD1 4.28Å; L96-L100 HydrophobicContact CD1-CG 4.32Å; L96-L100 HydrophobicContact CG-CD1 4.06Å; L96-L100 WeakPolarHBondContact O-CB 3.42Å; L96-L100 VanDerWaalsContact O-CG 3.27Å; L96-L100 WeakPolarHBondContact O-CG 3.13Å; L96-L100 PolarHBondContact O-N 2.96Å
97	L	75.1	Confident	74.4	Confident	26 Å²	26	69.1 Å²	69.1	14%	0.136	36%	0.359	C	S	.	.	H	α-helix	trans	-59.2	-45	176.8	-179.9	63.9	0	0	0	111.4	V27 L31 L93 W94 I95 L100 M101	V27-L97 HydrophobicContact CG1-CD1 4.19Å; L31-L97 HydrophobicContact CD1-CD2 4.22Å; L31-L97 HydrophobicContact CD2-CD2 4.47Å; L93-L97 WeakPolarHBondContact O-CB 3.19Å; L93-L97 PolarHBondContact O-N 2.91Å; W94-L97 HydrophobicContact CE3-CD2 4.35Å; W94-L97 HydrophobicContact CZ3-CD2 4.49Å; W94-L97 PolarHBondContact O-N 3.03Å; I95-L97 PolarHBondContact O-N 3.13Å; L97-L100 PolarHBondContact O-N 3.47Å; L97-M101 WeakPolarHBondContact O-CB 3.44Å; L97-M101 VanDerWaalsContact O-CG 3.25Å; L97-M101 WeakPolarHBondContact O-CG 3.48Å; L97-M101 PolarHBondContact O-N 3.41Å
98	A	72	Confident	74.7	Confident	0 Å²	0	66.7 Å²	66.7	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-67.4	-38.7	178.9	0	0	0	0	0	113	W94 I95 L96 M101 K102 V124 I382	W94-A98 PolarHBondContact O-N 2.92Å; I95-A98 PolarHBondContact O-N 3.48Å; L96-A98 VanDerWaalsContact C-N 3.35Å; L96-A98 PolarHBondContact O-N 3.46Å; A98-M101 PolarHBondContact O-N 2.77Å; A98-K102 WeakPolarHBondContact O-CB 3.28Å; A98-K102 PolarHBondContact O-N 3.25Å; A98-V124 HydrophobicContact CB-CG1 4.25Å; A98-I382 HydrophobicContact CB-CD1 3.25Å; A98-I382 HydrophobicContact CB-CG1 4.07Å
99	L	76.9	Confident	74.3	Confident	72 Å²	72	68.1 Å²	68.1	38%	0.377	36%	0.357	S	S	.	.	H	α-helix	trans	-64.8	-39.2	173.4	-69.4	173.8	0	0	0	111.9	I95 L96 M101 K102 L103	I95-L99 HydrophobicContact CG2-CD1 4.03Å; I95-L99 HydrophobicContact CG2-CG 4.44Å; I95-L99 WeakPolarHBondContact O-CG 3.48Å; I95-L99 PolarHBondContact O-N 2.94Å; L96-L99 PolarHBondContact O-N 3.06Å; L99-M101 VanDerWaalsContact C-N 3.35Å; L99-K102 PolarHBondContact O-N 2.99Å; L99-L103 WeakPolarHBondContact O-CB 3Å; L99-L103 PolarHBondContact O-N 3.3Å
100	L	79.6	Confident	74	Confident	99 Å²	99	73 Å²	73	52%	0.518	37%	0.373	S	S	.	.	H	α-helix	trans	-65.3	-37	173.4	-72.7	171	0	0	0	112.1	L96 L97 G104	L96-L100 HydrophobicContact CD1-CD1 4.28Å; L96-L100 HydrophobicContact CD1-CG 4.32Å; L96-L100 HydrophobicContact CG-CD1 4.06Å; L96-L100 WeakPolarHBondContact O-CB 3.42Å; L96-L100 VanDerWaalsContact O-CG 3.27Å; L96-L100 WeakPolarHBondContact O-CG 3.13Å; L96-L100 PolarHBondContact O-N 2.96Å; L97-L100 PolarHBondContact O-N 3.47Å; L100-G104 PolarHBondContact O-N 2.81Å
101	M	72.9	Confident	73.8	Confident	42 Å²	42	74.4 Å²	74.4	21%	0.207	38%	0.381	C	S	.	.	H	α-helix	trans	-67.7	-43.4	174.8	-74.1	-69.5	-69.1	0	0	112.1	F24 L97 A98 L99 G104 F105 L120 V124	F24-M101 HydrophobicContact CE1-CE 3.81Å; F24-M101 HydrophobicContact CE1-SD 4.3Å; F24-M101 HydrophobicContact CZ-CE 3.64Å; F24-M101 HydrophobicContact CZ-SD 4.17Å; L97-M101 WeakPolarHBondContact O-CB 3.44Å; L97-M101 VanDerWaalsContact O-CG 3.25Å; L97-M101 WeakPolarHBondContact O-CG 3.48Å; L97-M101 PolarHBondContact O-N 3.41Å; A98-M101 PolarHBondContact O-N 2.77Å; L99-M101 VanDerWaalsContact C-N 3.35Å; M101-G104 PolarHBondContact O-N 2.78Å; M101-F105 WeakPolarHBondContact O-CB 3.48Å; M101-F105 PolarHBondContact O-N 3.01Å; M101-L120 HydrophobicContact CB-CD2 4.48Å; M101-V124 HydrophobicContact CB-CG2 4.09Å; M101-V124 HydrophobicContact CE-CG2 3.76Å; M101-V124 HydrophobicContact CG-CG2 4.16Å
102	K	73.9	Confident	73.5	Confident	40 Å²	40	73 Å²	73	17%	0.174	38%	0.377	C	S	.	.	H	α-helix	trans	-59.6	-43.1	173.2	175.6	163.8	166.9	154.2	0	111.8	A98 L99 H106 E117 S374 T378	A98-K102 WeakPolarHBondContact O-CB 3.28Å; A98-K102 PolarHBondContact O-N 3.25Å; L99-K102 PolarHBondContact O-N 2.99Å; K102-H106 PolarHBondContact O-N 2.77Å; K102-E117 VanDerWaalsContact CD-OE1 3.31Å; K102-E117 WeakPolarHBondContact CD-OE1 3.32Å; K102-E117 WeakPolarHBondContact CE-OE1 3.29Å; K102-E117 IonicContact NZ-OE1 3.05Å; K102-E117 PolarHBondContact NZ-OE1 3.43Å; K102-S374 PolarHBondContact NZ-OG 3.46Å; K102-T378 PolarHBondContact NZ-OG1 3.34Å
103	L	78.1	Confident	73.3	Confident	103 Å²	103	74.1 Å²	74.1	54%	0.539	37%	0.374	S	S	.	.	H	α-helix	trans	-64.4	-46.9	172.3	179.1	62.8	0	0	0	112.2	L99 F105 H106 I107	L99-L103 WeakPolarHBondContact O-CB 3Å; L99-L103 PolarHBondContact O-N 3.3Å; L103-F105 PolarHBondContact O-N 3.19Å; L103-H106 PolarHBondContact O-N 2.94Å; L103-I107 HydrophobicContact CD1-CD1 4.38Å; L103-I107 HydrophobicContact CG-CD1 4.13Å; L103-I107 WeakPolarHBondContact O-CG1 3.4Å; L103-I107 PolarHBondContact O-N 2.71Å
104	G	72.1	Confident	73.2	Confident	27 Å²	27	76.4 Å²	76.4	28%	0.278	39%	0.385	S	S	.	.	H	α-helix	trans	-59.8	-34.4	179.1	0	0	0	0	0	113	L100 M101 I107 I108	L100-G104 PolarHBondContact O-N 2.81Å; M101-G104 PolarHBondContact O-N 2.78Å; G104-I107 PolarHBondContact O-N 3.25Å; G104-I108 WeakPolarHBondContact O-CG1 3.35Å; G104-I108 PolarHBondContact O-N 3.15Å
105	F	70.1	Confident	73.5	Confident	18 Å²	18	75.4 Å²	75.4	8%	0.079	38%	0.384	C	S	.	.	H	α-helix	trans	-67.7	-43.9	174.7	-176.9	-106.6	0	0	0	113.2	M101 L103 I107 I108 I111 S112 V115 L120	M101-F105 WeakPolarHBondContact O-CB 3.48Å; M101-F105 PolarHBondContact O-N 3.01Å; L103-F105 PolarHBondContact O-N 3.19Å; F105-I107 PolarHBondContact O-N 3Å; F105-I108 CarbonylContact O-C 3.59Å; F105-I108 PolarHBondContact O-N 3Å; F105-I111 HydrophobicContact CD2-CB 4.04Å; F105-I111 HydrophobicContact CD2-CG2 4.16Å; F105-I111 HydrophobicContact CE2-CB 3.65Å; F105-I111 HydrophobicContact CE2-CG2 3.49Å; F105-I111 VanDerWaalsContact CE2-CG2 3.49Å; F105-I111 HydrophobicContact CZ-CG2 4.45Å; F105-S112 VanDerWaalsContact CE1-CA 3.47Å; F105-V115 HydrophobicContact CE2-CB 4.28Å; F105-V115 HydrophobicContact CZ-CB 4.1Å; F105-V115 WeakPolarHBondContact CZ-O 3.33Å; F105-L120 HydrophobicContact CB-CD1 3.8Å; F105-L120 HydrophobicContact CD1-CD1 4.47Å; F105-L120 HydrophobicContact CD2-CD1 3.14Å; F105-L120 HydrophobicContact CE2-CD1 3.6Å; F105-L120 HydrophobicContact CG-CD1 3.6Å; F105-L120 HydrophobicContact CZ-CD1 4.44Å
106	H	72.8	Confident	73.7	Confident	151 Å²	151	74 Å²	74	70%	0.699	38%	0.379	S	S	*	.	H	α-helix	trans	-63.1	-25.3	176.9	-159.2	72.6	0	0	0	112.4	K102 L103 I108	K102-H106 PolarHBondContact O-N 2.77Å; L103-H106 PolarHBondContact O-N 2.94Å; H106-I108 VanDerWaalsContact C-N 3.35Å
107	I	76.9	Confident	73.7	Confident	122 Å²	122	73 Å²	73	63%	0.626	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.5	-18.4	173.2	-65	164.5	0	0	0	112.4	L103 G104 F105 P109	L103-I107 HydrophobicContact CD1-CD1 4.38Å; L103-I107 HydrophobicContact CG-CD1 4.13Å; L103-I107 WeakPolarHBondContact O-CG1 3.4Å; L103-I107 PolarHBondContact O-N 2.71Å; G104-I107 PolarHBondContact O-N 3.25Å; F105-I107 PolarHBondContact O-N 3Å; I107-P109 WeakPolarHBondContact O-CD 3.42Å
108	I	76.6	Confident	74.1	Confident	72 Å²	72	72 Å²	72	37%	0.369	37%	0.367	S	S	.	.			trans	-109.8	83.9	-178.8	-52.9	166.2	0	0	0	110.2	G104 F105 H106 R110 I111 S112	G104-I108 WeakPolarHBondContact O-CG1 3.35Å; G104-I108 PolarHBondContact O-N 3.15Å; F105-I108 CarbonylContact O-C 3.59Å; F105-I108 PolarHBondContact O-N 3Å; H106-I108 VanDerWaalsContact C-N 3.35Å; I108-R110 PolarHBondContact O-N 3.29Å; I108-I111 HydrophobicContact CB-CD1 4.4Å; I108-I111 HydrophobicContact CB-CG1 4.47Å; I108-I111 HydrophobicContact CD1-CD1 4.36Å; I108-I111 HydrophobicContact CG2-CD1 3.86Å; I108-I111 HydrophobicContact CG2-CG1 3.74Å; I108-I111 PolarHBondContact O-N 3.07Å; I108-I111 VanDerWaalsContact O-N 3.09Å; I108-S112 PolarHBondContact O-N 3.03Å
109	P	67.8	Low	74.6	Confident	98 Å²	98	72.1 Å²	72.1	64%	0.636	37%	0.367	S	S	*	.	H	α-helix	trans	-61.9	-22.7	-170.8	23.4	-35.3	0	0	0	114.4	I107 H113	I107-P109 WeakPolarHBondContact O-CD 3.42Å; P109-H113 PolarHBondContact O-N 2.76Å
110	R	69.4	Low	74.9	Confident	214 Å²	214	70 Å²	70	81%	0.808	36%	0.356	S	S	*	.	H	α-helix	trans	-65.8	-36.4	176.6	-78.3	-170.4	177.1	175.2	-0	113.6	I108	I108-R110 PolarHBondContact O-N 3.29Å
111	I	68.9	Low	75.1	Confident	74 Å²	74	65.3 Å²	65.3	38%	0.379	33%	0.332	S	S	.	.	H	α-helix	trans	-85	-37.8	-178.1	-39.6	175.8	0	0	0	109.2	F105 I108 H113 I114 V115	F105-I111 HydrophobicContact CD2-CB 4.04Å; F105-I111 HydrophobicContact CD2-CG2 4.16Å; F105-I111 HydrophobicContact CE2-CB 3.65Å; F105-I111 HydrophobicContact CE2-CG2 3.49Å; F105-I111 VanDerWaalsContact CE2-CG2 3.49Å; F105-I111 HydrophobicContact CZ-CG2 4.45Å; I108-I111 HydrophobicContact CB-CD1 4.4Å; I108-I111 HydrophobicContact CB-CG1 4.47Å; I108-I111 HydrophobicContact CD1-CD1 4.36Å; I108-I111 HydrophobicContact CG2-CD1 3.86Å; I108-I111 HydrophobicContact CG2-CG1 3.74Å; I108-I111 PolarHBondContact O-N 3.07Å; I108-I111 VanDerWaalsContact O-N 3.09Å; I111-H113 PolarHBondContact O-N 2.95Å; I111-I114 PolarHBondContact O-N 3.4Å; I111-V115 HydrophobicContact CG2-CB 4.3Å; I111-V115 HydrophobicContact CG2-CG2 3.72Å; I111-V115 PolarHBondContact O-N 3.25Å
112	S	66.3	Low	75.8	Confident	41 Å²	41	63.3 Å²	63.3	29%	0.287	32%	0.322	S	S	.	.	H	α-helix	trans	-60.6	-21.8	174.2	-168.4	0	0	0	0	115.1	F105 I108	F105-S112 VanDerWaalsContact CE1-CA 3.47Å; I108-S112 PolarHBondContact O-N 3.03Å
113	H	69.7	Low	76.4	Confident	97 Å²	97	67 Å²	67	45%	0.449	34%	0.338	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79	-27.9	173.9	-169.6	-72.1	0	0	0	113.1	P109 I111 R488	P109-H113 PolarHBondContact O-N 2.76Å; I111-H113 PolarHBondContact O-N 2.95Å; H113-R488 PolarHBondContact CE1-NE 3.49Å; H113-R488 PolarHBondContact NE2-NE 2.88Å; H113-R488 PolarHBondContact NE2-NH2 2.87Å; H113-R488 WeakPolarHBondContact O-CD 3.01Å
114	I	74.2	Confident	76.7	Confident	110 Å²	110	62.4 Å²	62.4	56%	0.564	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.6	-34.9	-168.4	-60.7	172.4	0	0	0	111.7	I111	I111-I114 PolarHBondContact O-N 3.4Å
115	V	77.4	Confident	77.4	Confident	26 Å²	26	61.1 Å²	61.1	16%	0.158	30%	0.301	C	S	.	.	S	Bend	trans	-111.8	126	-169.9	-172.9	0	0	0	0	109.5	F105 I111 C119 M485	F105-V115 HydrophobicContact CE2-CB 4.28Å; F105-V115 HydrophobicContact CZ-CB 4.1Å; F105-V115 WeakPolarHBondContact CZ-O 3.33Å; I111-V115 HydrophobicContact CG2-CB 4.3Å; I111-V115 HydrophobicContact CG2-CG2 3.72Å; I111-V115 PolarHBondContact O-N 3.25Å; V115-C119 HydrophobicContact CG1-CB 3.7Å; V115-M485 HydrophobicContact CB-CE 4.37Å; V115-M485 HydrophobicContact CG1-CE 4.14Å; V115-M485 HydrophobicContact CG2-CE 3.69Å
116	P	78.7	Confident	78.2	Confident	23 Å²	23	62.5 Å²	62.5	15%	0.149	31%	0.309	C	S	.	.			trans	-62.1	147.1	169.3	-22	31.8	0	0	0	112.1	S118 C119 A227 G484	P116-S118 VanDerWaalsContact C-N 3.29Å; P116-S118 PolarHBondContact O-N 2.9Å; P116-C119 WeakPolarHBondContact O-CB 3.21Å; P116-C119 PolarHBondContact O-N 2.98Å; P116-A227 HydrophobicContact CB-CB 3.91Å; P116-A227 HydrophobicContact CG-CB 4.4Å; P116-G484 WeakPolarHBondContact CG-O 3.41Å
117	E	79.3	Confident	78.8	Confident	78 Å²	78	58.5 Å²	58.5	36%	0.364	29%	0.293	S	S	.	.	H	α-helix	trans	-54.3	-44.6	179.9	-167.6	179.8	139.9	0	0	112.3	K102 C119 L120 L121	K102-E117 VanDerWaalsContact CD-OE1 3.31Å; K102-E117 WeakPolarHBondContact CD-OE1 3.32Å; K102-E117 WeakPolarHBondContact CE-OE1 3.29Å; K102-E117 IonicContact NZ-OE1 3.05Å; K102-E117 PolarHBondContact NZ-OE1 3.43Å; E117-C119 VanDerWaalsContact C-N 3.28Å; E117-C119 PolarHBondContact O-N 3.03Å; E117-L120 PolarHBondContact O-N 2.92Å; E117-L120 VanDerWaalsContact O-N 3.08Å; E117-L121 HydrophobicContact CG-CD1 4.17Å; E117-L121 WeakPolarHBondContact O-CG 3.46Å; E117-L121 PolarHBondContact O-N 3.02Å; E117-L121 VanDerWaalsContact O-N 3.1Å
118	S	81.8	Confident	79.1	Confident	6 Å²	6	52.9 Å²	52.9	4%	0.042	26%	0.264	C	S	.	.	H	α-helix	trans	-56.9	-36.1	178.5	-36.3	0	0	0	0	113.2	P116 L121 I122	P116-S118 VanDerWaalsContact C-N 3.29Å; P116-S118 PolarHBondContact O-N 2.9Å; S118-L121 PolarHBondContact O-N 3.39Å; S118-I122 VanDerWaalsContact O-CG1 3.3Å; S118-I122 WeakPolarHBondContact O-CG1 3.16Å; S118-I122 PolarHBondContact O-N 3.09Å; S118-I122 VanDerWaalsContact O-N 3.08Å
119	C	83.5	Confident	79.4	Confident	2 Å²	2	49.6 Å²	49.6	1%	0.014	25%	0.248	C	C	.	.	H	α-helix	trans	-64.5	-41.8	177.6	-65	0	0	0	0	111.6	V115 P116 E117 F123 V480 F481	V115-C119 HydrophobicContact CG1-CB 3.7Å; P116-C119 WeakPolarHBondContact O-CB 3.21Å; P116-C119 PolarHBondContact O-N 2.98Å; E117-C119 VanDerWaalsContact C-N 3.28Å; E117-C119 PolarHBondContact O-N 3.03Å; C119-F123 WeakPolarHBondContact O-CB 3.4Å; C119-F123 PolarHBondContact O-N 2.99Å; C119-V480 VanDerWaalsContact SG-CG1 3.57Å; C119-V480 PolarHBondContact SG-O 2.74Å; C119-F481 HydrophobicContact CB-CD1 4.31Å; C119-F481 HydrophobicContact CB-CE1 4.11Å; C119-F481 HydrophobicContact CB-CZ 4.44Å
120	L	82.3	Confident	80.2	Confident	27 Å²	27	46.5 Å²	46.5	14%	0.141	23%	0.233	C	C	.	.	H	α-helix	trans	-68	-41.3	178.9	-179	148.7	0	0	0	111	M101 F105 E117 I122 F123 V124	M101-L120 HydrophobicContact CB-CD2 4.48Å; F105-L120 HydrophobicContact CB-CD1 3.8Å; F105-L120 HydrophobicContact CD1-CD1 4.47Å; F105-L120 HydrophobicContact CD2-CD1 3.14Å; F105-L120 HydrophobicContact CE2-CD1 3.6Å; F105-L120 HydrophobicContact CG-CD1 3.6Å; F105-L120 HydrophobicContact CZ-CD1 4.44Å; E117-L120 PolarHBondContact O-N 2.92Å; E117-L120 VanDerWaalsContact O-N 3.08Å; L120-I122 PolarHBondContact O-N 3.48Å; L120-F123 PolarHBondContact O-N 3.46Å; L120-V124 HydrophobicContact CD2-CG2 3.95Å; L120-V124 WeakPolarHBondContact O-CG2 3.14Å; L120-V124 PolarHBondContact O-N 3.34Å
121	L	84.3	Confident	80.8	Confident	0 Å²	0	38.4 Å²	38.4	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-63.1	-41.4	178.9	-66.3	173.1	0	0	0	111.9	E117 S118 V124 G125 T378 F381	E117-L121 HydrophobicContact CG-CD1 4.17Å; E117-L121 WeakPolarHBondContact O-CG 3.46Å; E117-L121 PolarHBondContact O-N 3.02Å; E117-L121 VanDerWaalsContact O-N 3.1Å; S118-L121 PolarHBondContact O-N 3.39Å; L121-V124 PolarHBondContact O-N 2.95Å; L121-G125 PolarHBondContact O-N 3.42Å; L121-T378 HydrophobicContact CD2-CG2 3.94Å; L121-F381 HydrophobicContact CB-CB 3.67Å; L121-F381 HydrophobicContact CB-CG 4.49Å; L121-F381 HydrophobicContact CD1-CB 4.42Å; L121-F381 HydrophobicContact CD1-CD2 4.09Å
122	I	87.6	Confident	81.3	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-64.2	-42.5	172.8	-65	168.6	0	0	0	111.1	S118 L120 V124 G125 L126 F381 L384 F477 V480 F481	S118-I122 VanDerWaalsContact O-CG1 3.3Å; S118-I122 WeakPolarHBondContact O-CG1 3.16Å; S118-I122 PolarHBondContact O-N 3.09Å; S118-I122 VanDerWaalsContact O-N 3.08Å; L120-I122 PolarHBondContact O-N 3.48Å; I122-V124 VanDerWaalsContact C-N 3.34Å; I122-V124 PolarHBondContact O-N 2.91Å; I122-G125 PolarHBondContact O-N 2.99Å; I122-L126 PolarHBondContact O-N 3.38Å; I122-F381 HydrophobicContact CD1-CD1 4.05Å; I122-F381 HydrophobicContact CG1-CB 4.1Å; I122-F381 HydrophobicContact CG1-CD1 4.01Å; I122-F381 HydrophobicContact CG1-CG 4.4Å; I122-L384 HydrophobicContact CD1-CD2 3.68Å; I122-L384 HydrophobicContact CG1-CD2 3.92Å; I122-L384 HydrophobicContact CG1-CG 4.48Å; I122-F477 HydrophobicContact CG2-CE1 3.55Å; I122-F477 HydrophobicContact CG2-CE2 4.08Å; I122-F477 HydrophobicContact CG2-CZ 3.3Å; I122-V480 HydrophobicContact CD1-CB 4.38Å; I122-V480 HydrophobicContact CD1-CG1 3.85Å; I122-V480 HydrophobicContact CD1-CG2 4.5Å; I122-F481 HydrophobicContact CB-CE2 4.36Å; I122-F481 HydrophobicContact CB-CZ 4.47Å; I122-F481 HydrophobicContact CG2-CE2 4Å; I122-F481 HydrophobicContact CG2-CZ 4.32Å
123	F	86.8	Confident	82	Confident	117 Å²	117	39.9 Å²	39.9	51%	0.513	21%	0.206	S	C	.	.	H	α-helix	trans	-63.5	-38.3	177.1	-177.3	-96.9	0	0	0	112.6	C119 L120 L126 L127	C119-F123 WeakPolarHBondContact O-CB 3.4Å; C119-F123 PolarHBondContact O-N 2.99Å; L120-F123 PolarHBondContact O-N 3.46Å; F123-L126 PolarHBondContact O-N 3.38Å; F123-L127 PolarHBondContact O-N 2.95Å
124	V	84.6	Confident	82.6	Confident	7 Å²	7	39.4 Å²	39.4	4%	0.042	22%	0.219	C	C	.	.	H	α-helix	trans	-63.3	-44.6	171.5	170	0	0	0	0	110.5	A98 M101 L120 L121 I122 L126 L127 I128	A98-V124 HydrophobicContact CB-CG1 4.25Å; M101-V124 HydrophobicContact CB-CG2 4.09Å; M101-V124 HydrophobicContact CE-CG2 3.76Å; M101-V124 HydrophobicContact CG-CG2 4.16Å; L120-V124 HydrophobicContact CD2-CG2 3.95Å; L120-V124 WeakPolarHBondContact O-CG2 3.14Å; L120-V124 PolarHBondContact O-N 3.34Å; L121-V124 PolarHBondContact O-N 2.95Å; I122-V124 VanDerWaalsContact C-N 3.34Å; I122-V124 PolarHBondContact O-N 2.91Å; V124-L126 VanDerWaalsContact C-N 3.35Å; V124-L126 PolarHBondContact O-N 3.43Å; V124-L127 PolarHBondContact O-N 3.22Å; V124-I128 HydrophobicContact CG1-CD1 3.77Å; V124-I128 HydrophobicContact CG1-CG1 4.41Å; V124-I128 VanDerWaalsContact O-CG1 3.28Å; V124-I128 WeakPolarHBondContact O-CG1 3.44Å; V124-I128 PolarHBondContact O-N 2.91Å
125	G	86.2	Confident	83.1	Confident	0 Å²	0	38 Å²	38	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-58.8	-41.4	174.1	0	0	0	0	0	113.4	L121 I122 I128 G129 G385 V386	L121-G125 PolarHBondContact O-N 3.42Å; I122-G125 PolarHBondContact O-N 2.99Å; G125-I128 PolarHBondContact O-N 3.31Å; G125-G129 PolarHBondContact O-N 3.04Å; G125-G385 VanDerWaalsContact C-C 3.48Å; G125-G385 CarbonylContact O-C 3.58Å; G125-V386 VanDerWaalsContact O-CG2 3.29Å; G125-V386 WeakPolarHBondContact O-CG2 3.43Å; G125-V386 PolarHBondContact O-N 3.22Å
126	L	87.4	Confident	82.9	Confident	48 Å²	48	45.4 Å²	45.4	25%	0.251	25%	0.245	S	C	.	.	H	α-helix	trans	-62.6	-42.2	173.9	-78	175.2	0	0	0	112.5	I122 F123 V124 G130 G385 T388 V389 F477	I122-L126 PolarHBondContact O-N 3.38Å; F123-L126 PolarHBondContact O-N 3.38Å; V124-L126 VanDerWaalsContact C-N 3.35Å; V124-L126 PolarHBondContact O-N 3.43Å; L126-G130 PolarHBondContact O-N 3.29Å; L126-G385 WeakPolarHBondContact CD2-O 3.47Å; L126-T388 HydrophobicContact CD2-CG2 3.91Å; L126-V389 HydrophobicContact CD2-CG2 3.79Å; L126-F477 HydrophobicContact CD1-CE1 3.64Å; L126-F477 HydrophobicContact CD1-CZ 3.79Å; L126-F477 HydrophobicContact CD2-CZ 4.11Å; L126-F477 HydrophobicContact CG-CE1 4.41Å; L126-F477 HydrophobicContact CG-CZ 4.07Å
127	L	86.1	Confident	82.5	Confident	67 Å²	67	48.4 Å²	48.4	35%	0.351	26%	0.257	S	S	.	.	H	α-helix	trans	-63.2	-46	177	-168.3	161.5	0	0	0	110.4	F123 V124 G130 V131	F123-L127 PolarHBondContact O-N 2.95Å; V124-L127 PolarHBondContact O-N 3.22Å; L127-G130 PolarHBondContact O-N 3.2Å; L127-V131 HydrophobicContact CD2-CG2 4.1Å; L127-V131 WeakPolarHBondContact O-CG2 3.36Å; L127-V131 PolarHBondContact O-N 3.3Å
128	I	82.3	Confident	81.8	Confident	4 Å²	4	53.2 Å²	53.2	2%	0.021	28%	0.277	C	S	.	.	H	α-helix	trans	-59	-52.2	176.2	-69	171.3	0	0	0	110.8	W94 V124 G125 G130 V131 I132 I382 V386	W94-I128 HydrophobicContact CD2-CG2 3.75Å; W94-I128 HydrophobicContact CE3-CB 4.09Å; W94-I128 HydrophobicContact CE3-CD1 3.81Å; W94-I128 HydrophobicContact CE3-CG1 3.58Å; W94-I128 HydrophobicContact CE3-CG2 3.49Å; W94-I128 VanDerWaalsContact CE3-CG2 3.49Å; W94-I128 HydrophobicContact CG-CG2 4.43Å; W94-I128 HydrophobicContact CH2-CG2 4.01Å; W94-I128 HydrophobicContact CZ2-CG2 4.25Å; W94-I128 HydrophobicContact CZ3-CB 4.05Å; W94-I128 HydrophobicContact CZ3-CD1 4.43Å; W94-I128 HydrophobicContact CZ3-CG1 3.7Å; W94-I128 HydrophobicContact CZ3-CG2 3.64Å; V124-I128 HydrophobicContact CG1-CD1 3.77Å; V124-I128 HydrophobicContact CG1-CG1 4.41Å; V124-I128 VanDerWaalsContact O-CG1 3.28Å; V124-I128 WeakPolarHBondContact O-CG1 3.44Å; V124-I128 PolarHBondContact O-N 2.91Å; G125-I128 PolarHBondContact O-N 3.31Å; I128-G130 VanDerWaalsContact C-N 3.28Å; I128-G130 PolarHBondContact O-N 3.4Å; I128-V131 PolarHBondContact O-N 3.01Å; I128-I132 HydrophobicContact CG2-CD1 3.77Å; I128-I132 WeakPolarHBondContact O-CG1 3.3Å; I128-I132 PolarHBondContact O-N 3.27Å; I128-I382 HydrophobicContact CD1-CG2 4.23Å; I128-V386 HydrophobicContact CB-CG2 4.11Å; I128-V386 HydrophobicContact CG2-CG2 3.76Å
129	G	82.3	Confident	80.9	Confident	3 Å²	3	53.4 Å²	53.4	3%	0.031	28%	0.278	C	S	.	.	H	α-helix	trans	-60.8	-36.3	177.6	0	0	0	0	0	112.9	G125 I132 K133 V389	G125-G129 PolarHBondContact O-N 3.04Å; G129-I132 PolarHBondContact O-N 3.48Å; G129-K133 VanDerWaalsContact O-CB 3.3Å; G129-K133 WeakPolarHBondContact O-CB 3.3Å; G129-K133 PolarHBondContact O-N 2.82Å; G129-V389 WeakPolarHBondContact O-CG1 3.45Å
130	G	84.6	Confident	79.8	Confident	32 Å²	32	55.8 Å²	55.8	33%	0.33	29%	0.294	S	S	.	.	H	α-helix	trans	-63.1	-43.3	174.1	0	0	0	0	0	113	L126 L127 I128 A134	L126-G130 PolarHBondContact O-N 3.29Å; L127-G130 PolarHBondContact O-N 3.2Å; I128-G130 VanDerWaalsContact C-N 3.28Å; I128-G130 PolarHBondContact O-N 3.4Å; G130-A134 WeakPolarHBondContact O-CB 3.45Å; G130-A134 PolarHBondContact O-N 3.26Å
131	V	83.6	Confident	78.9	Confident	44 Å²	44	57.6 Å²	57.6	27%	0.267	31%	0.306	S	S	.	.	H	α-helix	trans	-66.2	-45.3	175.8	170.7	0	0	0	0	111.2	W94 L127 I128 K133 A134 I135	W94-V131 HydrophobicContact CH2-CG1 4.37Å; L127-V131 HydrophobicContact CD2-CG2 4.1Å; L127-V131 WeakPolarHBondContact O-CG2 3.36Å; L127-V131 PolarHBondContact O-N 3.3Å; I128-V131 PolarHBondContact O-N 3.01Å; V131-K133 VanDerWaalsContact C-N 3.35Å; V131-K133 PolarHBondContact O-N 3.43Å; V131-A134 WeakPolarHBondContact O-CB 3.36Å; V131-A134 PolarHBondContact O-N 3.47Å; V131-A134 VanDerWaalsContact O-N 3.13Å; V131-I135 HydrophobicContact CG1-CD1 3.74Å; V131-I135 WeakPolarHBondContact O-CG1 3.5Å; V131-I135 PolarHBondContact O-N 3.12Å
132	I	79.4	Confident	77.9	Confident	14 Å²	14	58.1 Å²	58.1	7%	0.072	31%	0.309	C	S	.	.	H	α-helix	trans	-60	-45.9	177.7	-65.3	165.3	0	0	0	110.7	W94 I128 G129 A134 I135 Q136 E137 A139	W94-I132 HydrophobicContact CH2-CG1 4.16Å; W94-I132 HydrophobicContact CZ2-CD1 3.91Å; W94-I132 HydrophobicContact CZ2-CG1 3.72Å; I128-I132 HydrophobicContact CG2-CD1 3.77Å; I128-I132 WeakPolarHBondContact O-CG1 3.3Å; I128-I132 PolarHBondContact O-N 3.27Å; G129-I132 PolarHBondContact O-N 3.48Å; I132-A134 VanDerWaalsContact C-N 3.29Å; I132-A134 PolarHBondContact O-N 2.93Å; I132-I135 CarbonylContact O-C 3.52Å; I132-I135 PolarHBondContact O-N 3.33Å; I132-I135 VanDerWaalsContact O-N 3.11Å; I132-Q136 PolarHBondContact O-N 3.28Å; I132-E137 HydrophobicContact CG2-CB 4.46Å; I132-E137 WeakPolarHBondContact CG2-O 3.25Å; I132-E137 PolarHBondContact O-N 3.47Å; I132-A139 HydrophobicContact CB-CB 4.42Å; I132-A139 HydrophobicContact CD1-CB 4.15Å; I132-A139 HydrophobicContact CG2-CB 3.71Å
133	K	80.5	Confident	77.2	Confident	132 Å²	132	62.6 Å²	62.6	57%	0.574	33%	0.332	S	S	*	.	H	α-helix	trans	-63.4	-32.5	176	-172.9	167.9	-174.5	170.1	0	113.1	G129 V131 Q136 V389	G129-K133 VanDerWaalsContact O-CB 3.3Å; G129-K133 WeakPolarHBondContact O-CB 3.3Å; G129-K133 PolarHBondContact O-N 2.82Å; V131-K133 VanDerWaalsContact C-N 3.35Å; V131-K133 PolarHBondContact O-N 3.43Å; K133-Q136 PolarHBondContact O-N 2.83Å; K133-V389 HydrophobicContact CB-CG1 4.02Å; K133-V389 HydrophobicContact CD-CG1 3.54Å; K133-V389 HydrophobicContact CG-CG1 4.45Å; K133-V389 PolarHBondContact NZ-O 3.26Å
134	A	82.8	Confident	76.6	Confident	87 Å²	87	57.7 Å²	57.7	72%	0.719	31%	0.312	S	S	*	.	H	α-helix	trans	-73	-29.1	174	0	0	0	0	0	113.2	G130 V131 I132	G130-A134 WeakPolarHBondContact O-CB 3.45Å; G130-A134 PolarHBondContact O-N 3.26Å; V131-A134 WeakPolarHBondContact O-CB 3.36Å; V131-A134 PolarHBondContact O-N 3.47Å; V131-A134 VanDerWaalsContact O-N 3.13Å; I132-A134 VanDerWaalsContact C-N 3.29Å; I132-A134 PolarHBondContact O-N 2.93Å
135	I	83	Confident	76.5	Confident	81 Å²	81	64.4 Å²	64.4	42%	0.415	34%	0.341	S	S	.	.	H	α-helix	trans	-78.3	-8.8	171.3	-64.3	166.3	0	0	0	111.1	V131 I132 E137	V131-I135 HydrophobicContact CG1-CD1 3.74Å; V131-I135 WeakPolarHBondContact O-CG1 3.5Å; V131-I135 PolarHBondContact O-N 3.12Å; I132-I135 CarbonylContact O-C 3.52Å; I132-I135 PolarHBondContact O-N 3.33Å; I132-I135 VanDerWaalsContact O-N 3.11Å; I135-E137 HydrophobicContact CG2-CG 4.09Å; I135-E137 PolarHBondContact O-N 2.82Å
136	Q	73.6	Confident	76.3	Confident	182 Å²	182	67.9 Å²	67.9	85%	0.85	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	64.3	18	178.4	-150.8	169.1	9.2	0	0	114	I132 K133	I132-Q136 PolarHBondContact O-N 3.28Å; K133-Q136 PolarHBondContact O-N 2.83Å
137	E	70.3	Confident	76.2	Confident	86 Å²	86	65.7 Å²	65.7	40%	0.402	35%	0.348	S	S	.	.	P	Polyproline II helix	trans	-86	150.7	170.6	-74.6	-173.9	150.5	0	0	111.1	R86 I132 I135 A139	R86-E137 IonicContact CZ-OE1 2.84Å; R86-E137 IonicContact NH1-OE1 3.32Å; R86-E137 PolarHBondContact NH1-OE1 3.41Å; R86-E137 IonicContact NH2-OE1 2.65Å; R86-E137 PolarHBondContact NH2-OE1 3.25Å; R86-E137 IonicContact NH2-OE2 3.19Å; R86-E137 PolarHBondContact NH2-OE2 2.99Å; I132-E137 HydrophobicContact CG2-CB 4.46Å; I132-E137 WeakPolarHBondContact CG2-O 3.25Å; I132-E137 PolarHBondContact O-N 3.47Å; I135-E137 HydrophobicContact CG2-CG 4.09Å; I135-E137 PolarHBondContact O-N 2.82Å; E137-A139 PolarHBondContact O-N 2.96Å
138	K	65.4	Low	76.1	Confident	179 Å²	179	63.6 Å²	63.6	78%	0.778	34%	0.335	S	S	*	.	P	Polyproline II helix	trans	-73	125.9	175	-166.3	179.3	-177.6	178.2	0	108.5	E390	K138-E390 WeakPolarHBondContact CG-OE1 3.44Å
139	A	62	Low	76.3	Confident	9 Å²	9	66.1 Å²	66.1	7%	0.074	35%	0.349	C	S	.	.	P	Polyproline II helix	trans	-74.8	154.1	-178.4	0	0	0	0	0	110.2	I132 E137 V141 V386 E390	I132-A139 HydrophobicContact CB-CB 4.42Å; I132-A139 HydrophobicContact CD1-CB 4.15Å; I132-A139 HydrophobicContact CG2-CB 3.71Å; E137-A139 PolarHBondContact O-N 2.96Å; A139-V141 VanDerWaalsContact C-N 3.3Å; A139-V141 PolarHBondContact O-N 3.46Å; A139-V386 HydrophobicContact CB-CG1 3.77Å; A139-E390 VanDerWaalsContact CB-OE2 3.29Å; A139-E390 WeakPolarHBondContact CB-OE2 3.42Å; A139-E390 PolarHBondContact N-OE1 3.45Å
140	P	61.4	Low	76.5	Confident	53 Å²	53	72.6 Å²	72.6	34%	0.344	37%	0.373	S	S	.	.			trans	-71.3	89.2	172.8	28.4	-33	0	0	0	109.5	M142	P140-M142 PolarHBondContact O-N 2.92Å
141	V	62.8	Low	76.6	Confident	64 Å²	64	71.6 Å²	71.6	39%	0.388	36%	0.36	S	S	.	.	P	Polyproline II helix	trans	-57.5	133	169.3	-174.1	0	0	0	0	109.1	A139 D143 E390 Y453	A139-V141 VanDerWaalsContact C-N 3.3Å; A139-V141 PolarHBondContact O-N 3.46Å; V141-D143 PolarHBondContact O-N 3.28Å; V141-E390 WeakPolarHBondContact CG2-OE2 3.41Å; V141-Y453 HydrophobicContact CG1-CD1 4.43Å; V141-Y453 HydrophobicContact CG1-CE1 3.93Å
142	M	64.1	Low	76.9	Confident	12 Å²	12	69.7 Å²	69.7	6%	0.059	35%	0.349	C	S	.	.	P	Polyproline II helix	trans	-65.2	119.7	177.4	-175.6	-177.6	76	0	0	110.4	P140 T144 F147 L151 F383 F449	P140-M142 PolarHBondContact O-N 2.92Å; M142-T144 PolarHBondContact O-N 2.98Å; M142-F147 HydrophobicContact CE-CB 3.82Å; M142-F147 HydrophobicContact CE-CD2 3.64Å; M142-F147 HydrophobicContact CE-CG 4.01Å; M142-F147 HydrophobicContact SD-CB 4.02Å; M142-F147 HydrophobicContact SD-CD2 3.81Å; M142-F147 HydrophobicContact SD-CG 4.39Å; M142-L151 HydrophobicContact SD-CD1 4.15Å; M142-F383 HydrophobicContact CB-CB 4.13Å; M142-F383 HydrophobicContact CB-CD1 4.39Å; M142-F383 HydrophobicContact CB-CG 4.13Å; M142-F383 HydrophobicContact CG-CD2 4.32Å; M142-F383 HydrophobicContact CG-CG 4.41Å; M142-F383 HydrophobicContact SD-CB 4.07Å; M142-F383 HydrophobicContact SD-CD2 4.12Å; M142-F383 HydrophobicContact SD-CG 4.34Å; M142-F449 HydrophobicContact CE-CD1 4.15Å; M142-F449 HydrophobicContact CE-CE1 3.75Å
143	D	71.2	Confident	77.5	Confident	93 Å²	93	69.4 Å²	69.4	50%	0.497	35%	0.347	S	S	.	.	P	Polyproline II helix	trans	-66.6	124.7	167.1	-179.2	0.7	0	0	0	109.1	V141 K145 L146 F147	V141-D143 PolarHBondContact O-N 3.28Å; D143-K145 PolarHBondContact O-N 3.34Å; D143-K145 PolarHBondContact OD1-N 3.34Å; D143-L146 HydrophobicContact CB-CB 4.2Å; D143-L146 WeakPolarHBondContact O-CA 3.17Å; D143-L146 WeakPolarHBondContact O-CB 3.34Å; D143-L146 PolarHBondContact O-N 2.9Å; D143-F147 PolarHBondContact O-N 2.66Å
144	T	75.9	Confident	78.1	Confident	15 Å²	15	63.7 Å²	63.7	9%	0.092	32%	0.324	C	S	.	.	H	α-helix	trans	-55.7	-33.2	177	-50.1	0	0	0	0	112.2	M142 L146 F147 F148 L454	M142-T144 PolarHBondContact O-N 2.98Å; T144-L146 VanDerWaalsContact C-N 3.32Å; T144-L146 PolarHBondContact O-N 3.35Å; T144-F147 WeakPolarHBondContact O-CB 3.31Å; T144-F147 PolarHBondContact O-N 3.38Å; T144-F148 HydrophobicContact CG2-CD2 3.79Å; T144-F148 HydrophobicContact CG2-CE2 3.67Å; T144-F148 WeakPolarHBondContact O-CD2 3.27Å; T144-F148 PolarHBondContact O-N 2.9Å; T144-F148 VanDerWaalsContact O-N 3.16Å; T144-L454 HydrophobicContact CG2-CB 3.92Å; T144-L454 HydrophobicContact CG2-CD1 3.84Å; T144-L454 HydrophobicContact CG2-CD2 4.28Å; T144-L454 HydrophobicContact CG2-CG 4.22Å
145	K	81.3	Confident	78.5	Confident	147 Å²	147	61.9 Å²	61.9	64%	0.639	30%	0.302	S	S	*	.	H	α-helix	trans	-64.8	-37.2	174.9	-63.6	178.3	179.8	178.3	0	111.8	D143 F147 L149	D143-K145 PolarHBondContact O-N 3.34Å; D143-K145 PolarHBondContact OD1-N 3.34Å; K145-F147 VanDerWaalsContact C-N 3.32Å; K145-L149 VanDerWaalsContact O-CB 3.27Å; K145-L149 WeakPolarHBondContact O-CB 3.43Å; K145-L149 VanDerWaalsContact O-CG 3.29Å; K145-L149 WeakPolarHBondContact O-CG 3.29Å; K145-L149 PolarHBondContact O-N 3.26Å
146	L	81.8	Confident	78.9	Confident	74 Å²	74	58.7 Å²	58.7	39%	0.387	29%	0.285	S	S	.	.	H	α-helix	trans	-66.7	-36.6	177	-176.7	147.9	0	0	0	111.4	D143 T144 Y150 L151	D143-L146 HydrophobicContact CB-CB 4.2Å; D143-L146 WeakPolarHBondContact O-CA 3.17Å; D143-L146 WeakPolarHBondContact O-CB 3.34Å; D143-L146 PolarHBondContact O-N 2.9Å; T144-L146 VanDerWaalsContact C-N 3.32Å; T144-L146 PolarHBondContact O-N 3.35Å; L146-Y150 HydrophobicContact CG-CD2 4.32Å; L146-Y150 WeakPolarHBondContact O-CB 3.47Å; L146-Y150 PolarHBondContact O-N 3.09Å; L146-Y150 VanDerWaalsContact O-N 3.09Å; L146-L151 HydrophobicContact CD2-CD1 3.71Å; L146-L151 HydrophobicContact CD2-CD2 4.4Å; L146-L151 HydrophobicContact CD2-CG 3.86Å; L146-L151 PolarHBondContact O-N 3.43Å
147	F	85	Confident	79.8	Confident	2 Å²	2	50.5 Å²	50.5	1%	0.009	25%	0.247	C	C	.	.	I	π-helix	trans	-61	-56.9	174.1	179.6	-87.8	0	0	0	112.2	M142 D143 T144 K145 L151 L152 I380 I447 S450	M142-F147 HydrophobicContact CE-CB 3.82Å; M142-F147 HydrophobicContact CE-CD2 3.64Å; M142-F147 HydrophobicContact CE-CG 4.01Å; M142-F147 HydrophobicContact SD-CB 4.02Å; M142-F147 HydrophobicContact SD-CD2 3.81Å; M142-F147 HydrophobicContact SD-CG 4.39Å; D143-F147 PolarHBondContact O-N 2.66Å; T144-F147 WeakPolarHBondContact O-CB 3.31Å; T144-F147 PolarHBondContact O-N 3.38Å; K145-F147 VanDerWaalsContact C-N 3.32Å; F147-L151 HydrophobicContact CD2-CD1 4.49Å; F147-L151 PolarHBondContact O-N 3.39Å; F147-L152 HydrophobicContact CD1-CB 4.34Å; F147-L152 HydrophobicContact CD1-CD1 4.26Å; F147-L152 HydrophobicContact CE1-CB 4.2Å; F147-L152 HydrophobicContact CE1-CD1 3.54Å; F147-L152 HydrophobicContact CZ-CD1 4.22Å; F147-L152 VanDerWaalsContact O-CB 3.29Å; F147-L152 WeakPolarHBondContact O-CB 3.4Å; F147-L152 PolarHBondContact O-N 3.05Å; F147-I380 HydrophobicContact CD2-CD1 4.21Å; F147-I380 HydrophobicContact CD2-CG1 4.01Å; F147-I380 HydrophobicContact CE2-CD1 3.69Å; F147-I380 HydrophobicContact CE2-CG1 3.79Å; F147-I380 HydrophobicContact CE2-CG2 3.96Å; F147-I380 HydrophobicContact CZ-CD1 4.43Å; F147-I447 HydrophobicContact CE1-CG1 4.11Å; F147-I447 HydrophobicContact CZ-CB 4.46Å; F147-I447 HydrophobicContact CZ-CG1 3.8Å; F147-S450 WeakPolarHBondContact CB-OG 3.13Å; F147-S450 VanDerWaalsContact CD1-CB 3.44Å; F147-S450 WeakPolarHBondContact CD1-OG 3.18Å; F147-S450 VanDerWaalsContact CE1-CB 3.44Å; F147-S450 WeakPolarHBondContact CG-OG 3.46Å
148	F	84.1	Confident	80.9	Confident	22 Å²	22	47 Å²	47	10%	0.096	23%	0.231	C	C	.	.	I	π-helix	trans	-69.9	-38.9	-174.9	-76.9	-73.6	0	0	0	113.3	T144 L152 P153 V257 Y328 L451 L454	T144-F148 HydrophobicContact CG2-CD2 3.79Å; T144-F148 HydrophobicContact CG2-CE2 3.67Å; T144-F148 WeakPolarHBondContact O-CD2 3.27Å; T144-F148 PolarHBondContact O-N 2.9Å; T144-F148 VanDerWaalsContact O-N 3.16Å; F148-L152 HydrophobicContact CD1-CD1 3.93Å; F148-L152 HydrophobicContact CD1-CD2 4.39Å; F148-L152 HydrophobicContact CE1-CD1 3.96Å; F148-P153 VanDerWaalsContact O-CD 3.26Å; F148-P153 WeakPolarHBondContact O-CD 3.42Å; F148-P153 WeakPolarHBondContact O-CG 3.38Å; F148-V257 HydrophobicContact CE1-CG2 4.02Å; F148-Y328 PolarHBondContact O-OH 2.91Å; F148-L451 HydrophobicContact CE1-CD2 4.5Å; F148-L451 HydrophobicContact CE2-CD2 4.19Å; F148-L451 HydrophobicContact CZ-CD2 3.57Å; F148-L451 HydrophobicContact CZ-CG 3.98Å; F148-L454 HydrophobicContact CE2-CD2 4.34Å
149	L	86.3	Confident	82	Confident	57 Å²	57	39.4 Å²	39.4	30%	0.298	20%	0.202	S	C	.	.	I	π-helix	trans	-81.7	-31.6	-176.7	-60.9	178.3	0	0	0	113.9	K145 Y325 Y328 L329	K145-L149 VanDerWaalsContact O-CB 3.27Å; K145-L149 WeakPolarHBondContact O-CB 3.43Å; K145-L149 VanDerWaalsContact O-CG 3.29Å; K145-L149 WeakPolarHBondContact O-CG 3.29Å; K145-L149 PolarHBondContact O-N 3.26Å; L149-Y325 WeakPolarHBondContact O-CE2 3.32Å; L149-Y328 HydrophobicContact CD2-CE1 4.08Å; L149-L329 HydrophobicContact CD2-CD2 4.3Å
150	Y	86.7	Confident	83.4	Confident	140 Å²	140	39 Å²	39	55%	0.549	20%	0.199	S	C	.	.	I	π-helix	trans	-122	-40.1	-170.9	-60	-75.5	0	0	0	115.3	L146 P154	L146-Y150 HydrophobicContact CG-CD2 4.32Å; L146-Y150 WeakPolarHBondContact O-CB 3.47Å; L146-Y150 PolarHBondContact O-N 3.09Å; L146-Y150 VanDerWaalsContact O-N 3.09Å; Y150-P154 VanDerWaalsContact O-CD 3.29Å; Y150-P154 WeakPolarHBondContact O-CD 3.38Å; Y150-P154 WeakPolarHBondContact O-CG 3.29Å
151	L	87.4	Confident	84.8	Confident	11 Å²	11	36.5 Å²	36.5	6%	0.058	18%	0.183	C	C	.	.	I	π-helix	trans	-83.2	-42.2	-175.4	-59.5	178.4	0	0	0	112.2	M142 L146 F147 P154 S376 L379 I380 F383	M142-L151 HydrophobicContact SD-CD1 4.15Å; L146-L151 HydrophobicContact CD2-CD1 3.71Å; L146-L151 HydrophobicContact CD2-CD2 4.4Å; L146-L151 HydrophobicContact CD2-CG 3.86Å; L146-L151 PolarHBondContact O-N 3.43Å; F147-L151 HydrophobicContact CD2-CD1 4.49Å; F147-L151 PolarHBondContact O-N 3.39Å; L151-P154 WeakPolarHBondContact O-CD 3.01Å; L151-S376 WeakPolarHBondContact O-CB 3.22Å; L151-S376 PolarHBondContact O-OG 3.41Å; L151-L379 HydrophobicContact CD2-CB 4.23Å; L151-L379 HydrophobicContact CD2-CD1 3.69Å; L151-I380 HydrophobicContact CB-CD1 3.97Å; L151-I380 HydrophobicContact CB-CG1 4.03Å; L151-I380 HydrophobicContact CD1-CG1 3.88Å; L151-F383 HydrophobicContact CD1-CD2 4.42Å; L151-F383 HydrophobicContact CD1-CE2 4.45Å
152	L	89.5	Confident	86	Confident	4 Å²	4	35.6 Å²	35.6	2%	0.021	17%	0.174	C	C	.	.	H	α-helix	trans	-73	-43	-173.7	172.9	141	0	0	0	114.7	F147 F148 I155 I156 I339 I447	F147-L152 HydrophobicContact CD1-CB 4.34Å; F147-L152 HydrophobicContact CD1-CD1 4.26Å; F147-L152 HydrophobicContact CE1-CB 4.2Å; F147-L152 HydrophobicContact CE1-CD1 3.54Å; F147-L152 HydrophobicContact CZ-CD1 4.22Å; F147-L152 VanDerWaalsContact O-CB 3.29Å; F147-L152 WeakPolarHBondContact O-CB 3.4Å; F147-L152 PolarHBondContact O-N 3.05Å; F148-L152 HydrophobicContact CD1-CD1 3.93Å; F148-L152 HydrophobicContact CD1-CD2 4.39Å; F148-L152 HydrophobicContact CE1-CD1 3.96Å; L152-I155 PolarHBondContact O-N 3.37Å; L152-I156 HydrophobicContact CD1-CD1 4.25Å; L152-I156 HydrophobicContact CD2-CD1 3.27Å; L152-I156 HydrophobicContact CG-CD1 3.48Å; L152-I156 VanDerWaalsContact CG-CD1 3.48Å; L152-I156 PolarHBondContact O-N 3.42Å; L152-I339 HydrophobicContact CD1-CD1 4.21Å; L152-I339 HydrophobicContact CD2-CD1 4.16Å; L152-I339 HydrophobicContact CD2-CG1 4.09Å; L152-I447 HydrophobicContact CD1-CD1 3.98Å; L152-I447 HydrophobicContact CD1-CG1 4.01Å
153	P	92.3	Very high	87	Confident	7 Å²	7	35.2 Å²	35.2	5%	0.045	17%	0.172	C	C	.	.	H	α-helix	trans	-60.6	-41.5	-176.3	-24.7	35.6	0	0	0	115.2	F148 I155 I156 L157 Y325 Y328 L342	F148-P153 VanDerWaalsContact O-CD 3.26Å; F148-P153 WeakPolarHBondContact O-CD 3.42Å; F148-P153 WeakPolarHBondContact O-CG 3.38Å; P153-I155 VanDerWaalsContact C-N 3.27Å; P153-I155 PolarHBondContact O-N 3.11Å; P153-I156 PolarHBondContact O-N 3.33Å; P153-L157 VanDerWaalsContact O-CB 3.27Å; P153-L157 WeakPolarHBondContact O-CB 3.37Å; P153-L157 PolarHBondContact O-N 2.98Å; P153-Y325 HydrophobicContact CB-CD2 4.49Å; P153-Y328 HydrophobicContact CG-CD1 4.1Å; P153-Y328 HydrophobicContact CG-CE1 4.12Å; P153-Y328 HydrophobicContact CG-CG 4.39Å; P153-L342 HydrophobicContact CB-CD2 3.69Å; P153-L342 WeakPolarHBondContact O-CD2 3.29Å
154	P	92.4	Very high	87.7	Confident	13 Å²	13	33.6 Å²	33.6	8%	0.084	17%	0.167	C	C	.	.	H	α-helix	trans	-57.4	-36.1	175.6	-26.1	34.1	0	0	0	114.5	Y150 L151 D158 W372	Y150-P154 VanDerWaalsContact O-CD 3.29Å; Y150-P154 WeakPolarHBondContact O-CD 3.38Å; Y150-P154 WeakPolarHBondContact O-CG 3.29Å; L151-P154 WeakPolarHBondContact O-CD 3.01Å; P154-D158 PolarHBondContact O-N 2.91Å; P154-W372 HydrophobicContact CB-CB 4.29Å; P154-W372 HydrophobicContact CB-CD2 4.19Å; P154-W372 HydrophobicContact CB-CG 3.75Å; P154-W372 VanDerWaalsContact CG-CD1 3.49Å; P154-W372 HydrophobicContact CG-CD2 4.05Å; P154-W372 HydrophobicContact CG-CG 3.99Å; P154-W372 HydrophobicContact CG-CZ2 4.29Å; P154-W372 VanDerWaalsContact CG-NE1 3.26Å
155	I	91.2	Very high	88	Confident	48 Å²	48	35.6 Å²	35.6	25%	0.246	18%	0.176	C	C	.	.	H	α-helix	trans	-69.6	-50.7	-178.1	-60.6	172.1	0	0	0	110	L152 P153 L157 D158 A159 E377 I380	L152-I155 PolarHBondContact O-N 3.37Å; P153-I155 VanDerWaalsContact C-N 3.27Å; P153-I155 PolarHBondContact O-N 3.11Å; I155-L157 VanDerWaalsContact C-N 3.29Å; I155-L157 PolarHBondContact O-N 3.42Å; I155-D158 PolarHBondContact O-N 3.36Å; I155-A159 WeakPolarHBondContact O-CB 3.28Å; I155-A159 PolarHBondContact O-N 3.32Å; I155-E377 HydrophobicContact CD1-CB 4.41Å; I155-I380 HydrophobicContact CD1-CD1 3.52Å
156	I	92.2	Very high	87.9	Confident	14 Å²	14	38.1 Å²	38.1	7%	0.072	18%	0.181	C	C	.	.	H	α-helix	trans	-64.3	-35.6	178	-67.2	151.3	0	0	0	111.1	L152 P153 A159 G160 I339 L342 I343	L152-I156 HydrophobicContact CD1-CD1 4.25Å; L152-I156 HydrophobicContact CD2-CD1 3.27Å; L152-I156 HydrophobicContact CG-CD1 3.48Å; L152-I156 VanDerWaalsContact CG-CD1 3.48Å; L152-I156 PolarHBondContact O-N 3.42Å; P153-I156 PolarHBondContact O-N 3.33Å; I156-A159 PolarHBondContact O-N 3.43Å; I156-G160 PolarHBondContact O-N 2.83Å; I156-I339 HydrophobicContact CD1-CB 4.41Å; I156-I339 HydrophobicContact CD1-CD1 4.32Å; I156-I339 HydrophobicContact CD1-CG1 4.08Å; I156-I339 HydrophobicContact CD1-CG2 3.78Å; I156-I339 HydrophobicContact CG1-CG2 4.34Å; I156-I339 HydrophobicContact CG2-CG2 4.4Å; I156-L342 HydrophobicContact CB-CD2 3.88Å; I156-L342 HydrophobicContact CG2-CB 4.2Å; I156-L342 HydrophobicContact CG2-CD2 3.84Å; I156-L342 HydrophobicContact CG2-CG 3.98Å; I156-I343 HydrophobicContact CG2-CD1 4.25Å; I156-I343 HydrophobicContact CG2-CG1 3.49Å; I156-I343 VanDerWaalsContact CG2-CG1 3.49Å
157	L	92.9	Very high	88	Confident	10 Å²	10	35.8 Å²	35.8	5%	0.052	17%	0.173	C	C	.	.	H	α-helix	trans	-69.5	-41.5	178.4	-174.1	57.2	0	0	0	112.4	P153 I155 Y161 F321 S324 L342 L369	P153-L157 VanDerWaalsContact O-CB 3.27Å; P153-L157 WeakPolarHBondContact O-CB 3.37Å; P153-L157 PolarHBondContact O-N 2.98Å; I155-L157 VanDerWaalsContact C-N 3.29Å; I155-L157 PolarHBondContact O-N 3.42Å; L157-Y161 WeakPolarHBondContact O-CB 3.49Å; L157-Y161 PolarHBondContact O-N 2.96Å; L157-F321 HydrophobicContact CD2-CD1 4.09Å; L157-S324 WeakPolarHBondContact CD1-OG 3.48Å; L157-L342 HydrophobicContact CB-CD1 4.38Å; L157-L342 HydrophobicContact CD1-CD1 4.25Å; L157-L369 HydrophobicContact CB-CD2 4.11Å; L157-L369 HydrophobicContact CD2-CD2 3.89Å; L157-L369 HydrophobicContact CG-CD2 3.71Å
158	D	92.4	Very high	88.1	Confident	12 Å²	12	36.1 Å²	36.1	6%	0.064	18%	0.175	C	C	.	.	H	α-helix	trans	-58.4	-49.8	171.8	-178.1	53.9	0	0	0	110.3	P154 I155 F162 L369 K370 S373	P154-D158 PolarHBondContact O-N 2.91Å; I155-D158 PolarHBondContact O-N 3.36Å; D158-F162 WeakPolarHBondContact O-CB 3.44Å; D158-F162 WeakPolarHBondContact O-CD2 3.4Å; D158-F162 PolarHBondContact O-N 3.26Å; D158-F162 WeakPolarHBondContact OD1-CD2 3.46Å; D158-L369 HydrophobicContact CB-CB 4.33Å; D158-L369 HydrophobicContact CB-CD2 4.49Å; D158-K370 WeakPolarHBondContact OD2-CD 3.31Å; D158-K370 IonicContact OD2-NZ 3.76Å; D158-K370 PolarHBondContact OD2-NZ 3.07Å; D158-S373 PolarHBondContact OD2-OG 3.09Å
159	A	89.6	Confident	88	Confident	20 Å²	20	38 Å²	38	17%	0.165	19%	0.188	C	C	.	.	H	α-helix	trans	-65.4	-44.7	-177.7	0	0	0	0	0	112.9	I155 I156 L163 F246 L250	I155-A159 WeakPolarHBondContact O-CB 3.28Å; I155-A159 PolarHBondContact O-N 3.32Å; I156-A159 PolarHBondContact O-N 3.43Å; A159-L163 PolarHBondContact O-N 3.25Å; A159-L163 VanDerWaalsContact O-N 3.09Å; A159-F246 HydrophobicContact CB-CE2 4.02Å; A159-F246 HydrophobicContact CB-CZ 3.82Å; A159-L250 HydrophobicContact CB-CD1 3.68Å
160	G	90.3	Very high	87.8	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.01	20%	0.198	C	C	.	.	H	α-helix	trans	-72.5	-39.7	-179.9	0	0	0	0	0	113.7	I156 L163	I156-G160 PolarHBondContact O-N 2.83Å; G160-L163 WeakPolarHBondContact O-CB 3.38Å
161	Y	90.8	Very high	87.7	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-70.8	-40.8	177.7	-167.2	-91.4	0	0	0	111.3	L157 V320 R350 V353 I365 L369	L157-Y161 WeakPolarHBondContact O-CB 3.49Å; L157-Y161 PolarHBondContact O-N 2.96Å; Y161-V320 HydrophobicContact CD2-CG1 4.22Å; Y161-V320 HydrophobicContact CE2-CG1 3.9Å; Y161-R350 HydrophobicContact CD1-CG 4.26Å; Y161-R350 HydrophobicContact CD2-CB 4.01Å; Y161-R350 HydrophobicContact CE1-CG 4.13Å; Y161-R350 HydrophobicContact CE2-CB 3.98Å; Y161-R350 HydrophobicContact CE2-CG 4.4Å; Y161-R350 HydrophobicContact CG-CB 4.33Å; Y161-R350 HydrophobicContact CG-CG 4.45Å; Y161-R350 WeakPolarHBondContact O-CD 3.23Å; Y161-R350 VanDerWaalsContact O-CG 3.24Å; Y161-R350 WeakPolarHBondContact O-CG 3.5Å; Y161-R350 PolarHBondContact O-NH1 3.47Å; Y161-V353 WeakPolarHBondContact OH-CG1 3.39Å; Y161-I365 HydrophobicContact CE1-CG2 4.03Å; Y161-L369 HydrophobicContact CD1-CD1 4.08Å; Y161-L369 HydrophobicContact CG-CD1 4.2Å
162	F	88.3	Confident	87.6	Confident	46 Å²	46	37.5 Å²	37.5	20%	0.202	19%	0.19	C	C	.	.	H	α-helix	trans	-86.6	-3.9	-179.5	-67.8	-64	0	0	0	115.8	D158 R350 K366 L369	D158-F162 WeakPolarHBondContact O-CB 3.44Å; D158-F162 WeakPolarHBondContact O-CD2 3.4Å; D158-F162 PolarHBondContact O-N 3.26Å; D158-F162 WeakPolarHBondContact OD1-CD2 3.46Å; F162-R350 VanDerWaalsContact CA-NH1 3.32Å; F162-R350 PolarHBondContact O-NH1 3.06Å; F162-K366 HydrophobicContact CE1-CB 4.15Å; F162-K366 HydrophobicContact CE1-CD 4.45Å; F162-K366 HydrophobicContact CE1-CG 4.03Å; F162-K366 HydrophobicContact CE2-CB 4.37Å; F162-K366 HydrophobicContact CE2-CG 4.21Å; F162-K366 VanDerWaalsContact CZ-CA 3.48Å; F162-K366 HydrophobicContact CZ-CB 3.63Å; F162-K366 HydrophobicContact CZ-CG 3.73Å; F162-L369 HydrophobicContact CD2-CD1 4.38Å; F162-L369 HydrophobicContact CE2-CB 4.03Å; F162-L369 HydrophobicContact CE2-CD1 3.57Å; F162-L369 HydrophobicContact CE2-CG 4.44Å; F162-L369 HydrophobicContact CZ-CD1 4.21Å
163	L	86.5	Confident	87.6	Confident	3 Å²	3	39.8 Å²	39.8	2%	0.016	22%	0.215	C	C	.	.			trans	-45	122.5	171.7	-174.4	68.7	0	0	0	114	A159 G160 I165 F168 I243 F246 V347 R350	A159-L163 PolarHBondContact O-N 3.25Å; A159-L163 VanDerWaalsContact O-N 3.09Å; G160-L163 WeakPolarHBondContact O-CB 3.38Å; L163-I165 VanDerWaalsContact C-N 3.35Å; L163-I165 PolarHBondContact O-N 3.12Å; L163-F168 HydrophobicContact CD1-CB 4.27Å; L163-F168 HydrophobicContact CD1-CD2 3.69Å; L163-F168 HydrophobicContact CD1-CE2 4.11Å; L163-F168 HydrophobicContact CD1-CG 3.99Å; L163-F168 HydrophobicContact CD2-CB 4.31Å; L163-F168 HydrophobicContact CD2-CD1 3.6Å; L163-F168 HydrophobicContact CD2-CD2 4.03Å; L163-F168 HydrophobicContact CD2-CE1 3.75Å; L163-F168 HydrophobicContact CD2-CE2 4.16Å; L163-F168 HydrophobicContact CD2-CG 3.73Å; L163-F168 HydrophobicContact CD2-CZ 4.03Å; L163-F168 HydrophobicContact CG-CB 4.18Å; L163-F168 HydrophobicContact CG-CD1 4.38Å; L163-F168 HydrophobicContact CG-CD2 4.24Å; L163-F168 HydrophobicContact CG-CG 4.04Å; L163-I243 HydrophobicContact CD1-CD1 3.96Å; L163-F246 HydrophobicContact CB-CE1 4.49Å; L163-F246 HydrophobicContact CD1-CD1 3.76Å; L163-F246 HydrophobicContact CD1-CE1 3.45Å; L163-F246 VanDerWaalsContact CD1-CE1 3.45Å; L163-V347 HydrophobicContact CD2-CG2 3.6Å; L163-R350 PolarHBondContact O-NH1 2.98Å
164	P	84.1	Confident	87.4	Confident	60 Å²	60	40.3 Å²	40.3	39%	0.39	22%	0.218	S	C	.	.			trans	-72.2	86.2	178.2	29	-35.9	0	0	0	111.6	R166 A167 F168 I243	P164-R166 PolarHBondContact O-N 2.79Å; P164-A167 PolarHBondContact O-N 2.73Å; P164-A167 VanDerWaalsContact O-N 3.17Å; P164-F168 PolarHBondContact O-N 3.35Å; P164-F168 VanDerWaalsContact O-N 3.09Å; P164-I243 HydrophobicContact CG-CD1 3.67Å; P164-I243 HydrophobicContact CG-CG1 4.49Å
165	I	82.7	Confident	87.3	Confident	57 Å²	57	39.7 Å²	39.7	29%	0.292	21%	0.214	S	C	.	.	H	α-helix	trans	-51.8	-30.5	-168	-167.9	57	0	0	0	115.7	L163 T169 V347	L163-I165 VanDerWaalsContact C-N 3.35Å; L163-I165 PolarHBondContact O-N 3.12Å; I165-T169 HydrophobicContact CD1-CG2 3.79Å; I165-T169 HydrophobicContact CG1-CG2 4.2Å; I165-T169 WeakPolarHBondContact O-CB 3.26Å; I165-T169 VanDerWaalsContact O-CG2 3.31Å; I165-T169 WeakPolarHBondContact O-CG2 3.44Å; I165-T169 PolarHBondContact O-N 2.82Å; I165-T169 PolarHBondContact O-OG1 2.84Å; I165-V347 HydrophobicContact CD1-CG1 3.65Å
166	R	80.6	Confident	87.3	Confident	199 Å²	199	41.7 Å²	41.7	75%	0.751	22%	0.224	S	C	*	.	H	α-helix	trans	-70.2	-55.7	179.3	-63.7	-175	-174.1	178.6	3.6	111.5	P164 F168 T169 E170	P164-R166 PolarHBondContact O-N 2.79Å; R166-F168 PolarHBondContact O-N 3.35Å; R166-T169 PolarHBondContact O-N 3.38Å; R166-T169 PolarHBondContact O-OG1 3.18Å; R166-E170 WeakPolarHBondContact O-CB 3.29Å; R166-E170 WeakPolarHBondContact O-CG 3.42Å; R166-E170 PolarHBondContact O-N 2.86Å
167	A	83.1	Confident	87.3	Confident	26 Å²	26	43.3 Å²	43.3	22%	0.215	24%	0.235	C	C	.	.	H	α-helix	trans	-62.6	-34.8	178.5	0	0	0	0	0	111.6	P164 N171 I243	P164-A167 PolarHBondContact O-N 2.73Å; P164-A167 VanDerWaalsContact O-N 3.17Å; A167-N171 PolarHBondContact O-N 2.93Å; A167-N171 PolarHBondContact O-ND2 3.24Å; A167-I243 HydrophobicContact CB-CB 4.48Å; A167-I243 HydrophobicContact CB-CG1 4.16Å; A167-I243 HydrophobicContact CB-CG2 4.39Å
168	F	86.3	Confident	87.2	Confident	9 Å²	9	42.9 Å²	42.9	4%	0.039	23%	0.233	C	C	.	.	H	α-helix	trans	-66.6	-51.2	174.9	-171.8	-107.3	0	0	0	112.6	L163 P164 R166 E170 N171 M172 I175 I243 L251	L163-F168 HydrophobicContact CD1-CB 4.27Å; L163-F168 HydrophobicContact CD1-CD2 3.69Å; L163-F168 HydrophobicContact CD1-CE2 4.11Å; L163-F168 HydrophobicContact CD1-CG 3.99Å; L163-F168 HydrophobicContact CD2-CB 4.31Å; L163-F168 HydrophobicContact CD2-CD1 3.6Å; L163-F168 HydrophobicContact CD2-CD2 4.03Å; L163-F168 HydrophobicContact CD2-CE1 3.75Å; L163-F168 HydrophobicContact CD2-CE2 4.16Å; L163-F168 HydrophobicContact CD2-CG 3.73Å; L163-F168 HydrophobicContact CD2-CZ 4.03Å; L163-F168 HydrophobicContact CG-CB 4.18Å; L163-F168 HydrophobicContact CG-CD1 4.38Å; L163-F168 HydrophobicContact CG-CD2 4.24Å; L163-F168 HydrophobicContact CG-CG 4.04Å; P164-F168 PolarHBondContact O-N 3.35Å; P164-F168 VanDerWaalsContact O-N 3.09Å; R166-F168 PolarHBondContact O-N 3.35Å; F168-E170 VanDerWaalsContact C-N 3.35Å; F168-E170 PolarHBondContact O-N 3.04Å; F168-N171 CarbonylContact O-C 3.59Å; F168-N171 PolarHBondContact O-N 2.93Å; F168-M172 HydrophobicContact CD1-CE 3.61Å; F168-M172 HydrophobicContact CD1-SD 4.14Å; F168-M172 HydrophobicContact CE1-CE 3.38Å; F168-M172 HydrophobicContact CE1-SD 3.56Å; F168-M172 VanDerWaalsContact CE1-SD 3.56Å; F168-M172 HydrophobicContact CZ-CE 4.37Å; F168-M172 HydrophobicContact CZ-SD 3.98Å; F168-M172 WeakPolarHBondContact O-CA 3.34Å; F168-M172 PolarHBondContact O-N 3.03Å; F168-I175 HydrophobicContact CD2-CD1 3.5Å; F168-I175 HydrophobicContact CE2-CD1 3.8Å; F168-I175 HydrophobicContact CE2-CG2 4.03Å; F168-I175 HydrophobicContact CG-CD1 4.38Å; F168-I243 HydrophobicContact CB-CD1 4.21Å; F168-I243 HydrophobicContact CB-CG1 4.3Å; F168-I243 HydrophobicContact CD2-CD1 4.18Å; F168-I243 HydrophobicContact CD2-CG1 4.47Å; F168-L251 HydrophobicContact CZ-CD1 4.18Å
169	T	82.4	Confident	87.2	Confident	62 Å²	62	42.3 Å²	42.3	38%	0.38	23%	0.23	S	C	.	.	H	α-helix	trans	-66.5	-34.4	-178.9	49.2	0	0	0	0	113.1	I165 R166 N171 M172	I165-T169 HydrophobicContact CD1-CG2 3.79Å; I165-T169 HydrophobicContact CG1-CG2 4.2Å; I165-T169 WeakPolarHBondContact O-CB 3.26Å; I165-T169 VanDerWaalsContact O-CG2 3.31Å; I165-T169 WeakPolarHBondContact O-CG2 3.44Å; I165-T169 PolarHBondContact O-N 2.82Å; I165-T169 PolarHBondContact O-OG1 2.84Å; R166-T169 PolarHBondContact O-N 3.38Å; R166-T169 PolarHBondContact O-OG1 3.18Å; T169-N171 VanDerWaalsContact C-N 3.27Å; T169-N171 PolarHBondContact O-N 3.31Å; T169-M172 HydrophobicContact CG2-CE 4.17Å; T169-M172 WeakPolarHBondContact O-CB 3.44Å; T169-M172 PolarHBondContact O-N 3.47Å
170	E	82.8	Confident	87.3	Confident	109 Å²	109	42.6 Å²	42.6	51%	0.509	23%	0.229	S	C	.	.	H	α-helix	trans	-70	-21.5	176.2	-71.4	171.4	171.9	0	0	113.3	R166 F168 K535	R166-E170 WeakPolarHBondContact O-CB 3.29Å; R166-E170 WeakPolarHBondContact O-CG 3.42Å; R166-E170 PolarHBondContact O-N 2.86Å; F168-E170 VanDerWaalsContact C-N 3.35Å; F168-E170 PolarHBondContact O-N 3.04Å; E170-K535 IonicContact OE1-NZ 3.67Å; E170-K535 PolarHBondContact OE1-NZ 2.7Å
171	N	84.5	Confident	87.4	Confident	17 Å²	17	46.1 Å²	46.1	9%	0.091	25%	0.25	C	S	.	.	H	α-helix	trans	-113.3	7	177.2	-64.8	-82	0	0	0	113.5	A167 F168 T169 G173 T174 I175 L240 R426	A167-N171 PolarHBondContact O-N 2.93Å; A167-N171 PolarHBondContact O-ND2 3.24Å; F168-N171 CarbonylContact O-C 3.59Å; F168-N171 PolarHBondContact O-N 2.93Å; T169-N171 VanDerWaalsContact C-N 3.27Å; T169-N171 PolarHBondContact O-N 3.31Å; N171-G173 VanDerWaalsContact C-N 3.32Å; N171-G173 PolarHBondContact O-N 3.01Å; N171-G173 VanDerWaalsContact O-N 3.16Å; N171-T174 WeakPolarHBondContact O-CA 3.25Å; N171-T174 WeakPolarHBondContact O-CB 3.49Å; N171-T174 PolarHBondContact O-N 3.02Å; N171-I175 HydrophobicContact CB-CD1 4.2Å; N171-I175 HydrophobicContact CB-CG1 4.42Å; N171-I175 PolarHBondContact O-N 3.23Å; N171-I175 VanDerWaalsContact O-N 3.08Å; N171-L240 WeakPolarHBondContact ND2-CD2 3.42Å; N171-R426 PolarHBondContact OD1-NH2 3.3Å
172	M	86	Confident	87.5	Confident	71 Å²	71	46.3 Å²	46.3	35%	0.35	25%	0.253	S	S	.	.	H	α-helix	trans	-49.3	-48	-170.2	-177.1	75	77.1	0	0	113	F168 T169 T174 I175 L176	F168-M172 HydrophobicContact CD1-CE 3.61Å; F168-M172 HydrophobicContact CD1-SD 4.14Å; F168-M172 HydrophobicContact CE1-CE 3.38Å; F168-M172 HydrophobicContact CE1-SD 3.56Å; F168-M172 VanDerWaalsContact CE1-SD 3.56Å; F168-M172 HydrophobicContact CZ-CE 4.37Å; F168-M172 HydrophobicContact CZ-SD 3.98Å; F168-M172 WeakPolarHBondContact O-CA 3.34Å; F168-M172 PolarHBondContact O-N 3.03Å; T169-M172 HydrophobicContact CG2-CE 4.17Å; T169-M172 WeakPolarHBondContact O-CB 3.44Å; T169-M172 PolarHBondContact O-N 3.47Å; M172-T174 VanDerWaalsContact C-N 3.3Å; M172-T174 PolarHBondContact O-N 3.12Å; M172-I175 PolarHBondContact O-N 3.49Å; M172-L176 WeakPolarHBondContact O-CB 3.39Å; M172-L176 PolarHBondContact O-N 3.4Å
173	G	88	Confident	87.7	Confident	52 Å²	52	44.2 Å²	44.2	54%	0.536	24%	0.243	S	C	.	.	H	α-helix	trans	-64.2	-32.2	-179	0	0	0	0	0	113.7	N171 V177	N171-G173 VanDerWaalsContact C-N 3.32Å; N171-G173 PolarHBondContact O-N 3.01Å; N171-G173 VanDerWaalsContact O-N 3.16Å; G173-V177 VanDerWaalsContact O-CG2 3.27Å; G173-V177 WeakPolarHBondContact O-CG2 3.44Å; G173-V177 PolarHBondContact O-N 3.44Å
174	T	88.6	Confident	88.1	Confident	18 Å²	18	46.3 Å²	46.3	11%	0.11	25%	0.254	C	S	.	.	H	α-helix	trans	-70.7	-45.5	173.6	-64.4	0	0	0	0	110.6	N171 M172 V177 F178 L244 I422	N171-T174 WeakPolarHBondContact O-CA 3.25Å; N171-T174 WeakPolarHBondContact O-CB 3.49Å; N171-T174 PolarHBondContact O-N 3.02Å; M172-T174 VanDerWaalsContact C-N 3.3Å; M172-T174 PolarHBondContact O-N 3.12Å; T174-V177 PolarHBondContact O-N 2.87Å; T174-F178 HydrophobicContact CG2-CD2 3.94Å; T174-F178 HydrophobicContact CG2-CE2 3.65Å; T174-F178 WeakPolarHBondContact O-CD2 3.29Å; T174-F178 PolarHBondContact O-N 2.92Å; T174-F178 VanDerWaalsContact O-N 3.17Å; T174-L244 HydrophobicContact CG2-CD1 3.75Å; T174-L244 HydrophobicContact CG2-CG 4.47Å; T174-I422 HydrophobicContact CG2-CD1 4.37Å; T174-I422 HydrophobicContact CG2-CG2 4.08Å
175	I	90.9	Very high	88.5	Confident	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-62.1	-45.6	179.9	-62.3	173.3	0	0	0	110.6	F168 N171 M172 V177 F178 A179 I243 G247 L251	F168-I175 HydrophobicContact CD2-CD1 3.5Å; F168-I175 HydrophobicContact CE2-CD1 3.8Å; F168-I175 HydrophobicContact CE2-CG2 4.03Å; F168-I175 HydrophobicContact CG-CD1 4.38Å; N171-I175 HydrophobicContact CB-CD1 4.2Å; N171-I175 HydrophobicContact CB-CG1 4.42Å; N171-I175 PolarHBondContact O-N 3.23Å; N171-I175 VanDerWaalsContact O-N 3.08Å; M172-I175 PolarHBondContact O-N 3.49Å; I175-V177 VanDerWaalsContact C-N 3.34Å; I175-V177 PolarHBondContact O-N 2.83Å; I175-F178 PolarHBondContact O-N 3.38Å; I175-A179 WeakPolarHBondContact O-CB 3.41Å; I175-A179 PolarHBondContact O-N 3.46Å; I175-I243 HydrophobicContact CD1-CG1 4.46Å; I175-G247 WeakPolarHBondContact CG2-O 3.45Å; I175-L251 HydrophobicContact CG2-CD1 4.11Å
176	L	91.2	Very high	89	Confident	89 Å²	89	46.1 Å²	46.1	47%	0.466	24%	0.242	S	C	.	.	H	α-helix	trans	-62.4	-37.7	178.6	-169.7	71.5	0	0	0	112.4	M172 A179 V180	M172-L176 WeakPolarHBondContact O-CB 3.39Å; M172-L176 PolarHBondContact O-N 3.4Å; L176-A179 PolarHBondContact O-N 2.95Å; L176-V180 HydrophobicContact CD1-CG2 3.69Å; L176-V180 HydrophobicContact CG-CG2 4.14Å; L176-V180 WeakPolarHBondContact O-CB 3.38Å; L176-V180 WeakPolarHBondContact O-CG2 2.92Å; L176-V180 PolarHBondContact O-N 3.03Å
177	V	92.3	Very high	89.6	Confident	48 Å²	48	36.6 Å²	36.6	29%	0.291	21%	0.207	S	C	.	.	I	π-helix	trans	-66	-41.1	175.5	170.9	0	0	0	0	111.3	G173 T174 I175 V181 G182 L418 I422	G173-V177 VanDerWaalsContact O-CG2 3.27Å; G173-V177 WeakPolarHBondContact O-CG2 3.44Å; G173-V177 PolarHBondContact O-N 3.44Å; T174-V177 PolarHBondContact O-N 2.87Å; I175-V177 VanDerWaalsContact C-N 3.34Å; I175-V177 PolarHBondContact O-N 2.83Å; V177-V181 HydrophobicContact CG1-CB 4.34Å; V177-V181 HydrophobicContact CG1-CG2 4.33Å; V177-V181 WeakPolarHBondContact O-CA 3.31Å; V177-V181 VanDerWaalsContact O-CB 3.27Å; V177-V181 WeakPolarHBondContact O-CB 3.34Å; V177-V181 PolarHBondContact O-N 3.48Å; V177-G182 PolarHBondContact O-N 3.23Å; V177-G182 VanDerWaalsContact O-N 3.13Å; V177-L418 HydrophobicContact CG1-CD2 3.98Å; V177-I422 HydrophobicContact CB-CD1 4.25Å; V177-I422 HydrophobicContact CG1-CD1 3.81Å; V177-I422 HydrophobicContact CG1-CG1 4.03Å
178	F	89.9	Confident	90.1	Very high	2 Å²	2	40.5 Å²	40.5	1%	0.009	22%	0.219	C	C	.	.	I	π-helix	trans	-66.1	-46.5	173.3	-74.7	-67.8	0	0	0	112.3	T174 I175 G182 L244 E248 L418 T419 I422 L430	T174-F178 HydrophobicContact CG2-CD2 3.94Å; T174-F178 HydrophobicContact CG2-CE2 3.65Å; T174-F178 WeakPolarHBondContact O-CD2 3.29Å; T174-F178 PolarHBondContact O-N 2.92Å; T174-F178 VanDerWaalsContact O-N 3.17Å; I175-F178 PolarHBondContact O-N 3.38Å; F178-G182 VanDerWaalsContact O-CA 3.28Å; F178-G182 WeakPolarHBondContact O-CA 3.32Å; F178-G182 PolarHBondContact O-N 2.69Å; F178-L244 HydrophobicContact CD2-CD1 4.33Å; F178-L244 HydrophobicContact CD2-CD2 3.9Å; F178-L244 HydrophobicContact CD2-CG 4.18Å; F178-L244 HydrophobicContact CE2-CD1 3.89Å; F178-L244 HydrophobicContact CE2-CD2 3.95Å; F178-L244 HydrophobicContact CE2-CG 4.21Å; F178-E248 HydrophobicContact CB-CB 4.3Å; F178-E248 HydrophobicContact CB-CG 3.95Å; F178-L418 HydrophobicContact CD1-CB 4.28Å; F178-L418 HydrophobicContact CD1-CD1 3.91Å; F178-L418 HydrophobicContact CE1-CB 3.88Å; F178-L418 HydrophobicContact CE1-CD1 4.26Å; F178-T419 HydrophobicContact CE1-CG2 3.98Å; F178-T419 HydrophobicContact CZ-CG2 3.57Å; F178-I422 HydrophobicContact CD2-CD1 4.05Å; F178-I422 HydrophobicContact CE1-CD1 4.21Å; F178-I422 HydrophobicContact CE2-CD1 3.48Å; F178-I422 VanDerWaalsContact CE2-CD1 3.48Å; F178-I422 HydrophobicContact CZ-CD1 3.57Å; F178-L430 HydrophobicContact CE2-CD1 4.49Å; F178-L430 HydrophobicContact CZ-CD1 4.44Å
179	A	91.6	Very high	90.5	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	22%	0.224	C	C	.	.	I	π-helix	trans	-75.3	-23.2	-174	0	0	0	0	0	115.4	I175 L176 T183 L251	I175-A179 WeakPolarHBondContact O-CB 3.41Å; I175-A179 PolarHBondContact O-N 3.46Å; L176-A179 PolarHBondContact O-N 2.95Å; A179-T183 WeakPolarHBondContact O-CB 3.4Å; A179-T183 WeakPolarHBondContact O-CG2 3.35Å; A179-T183 PolarHBondContact O-OG1 3.19Å; A179-L251 HydrophobicContact CB-CB 3.45Å; A179-L251 VanDerWaalsContact CB-CB 3.45Å; A179-L251 HydrophobicContact CB-CD1 4.3Å
180	V	92.5	Very high	91	Very high	26 Å²	26	38.6 Å²	38.6	16%	0.158	21%	0.206	C	C	.	.	I	π-helix	trans	-108.4	-55.6	177.8	-176.8	0	0	0	0	111	L176 T183 L184 V255 F284	L176-V180 HydrophobicContact CD1-CG2 3.69Å; L176-V180 HydrophobicContact CG-CG2 4.14Å; L176-V180 WeakPolarHBondContact O-CB 3.38Å; L176-V180 WeakPolarHBondContact O-CG2 2.92Å; L176-V180 PolarHBondContact O-N 3.03Å; V180-T183 PolarHBondContact O-OG1 3.23Å; V180-L184 HydrophobicContact CG1-CD1 4.07Å; V180-L184 WeakPolarHBondContact O-CB 3.3Å; V180-L184 WeakPolarHBondContact O-CD1 3.15Å; V180-L184 WeakPolarHBondContact O-CG 3.49Å; V180-L184 PolarHBondContact O-N 2.82Å; V180-L184 VanDerWaalsContact O-N 3.1Å; V180-V255 HydrophobicContact CG2-CG2 4.07Å; V180-F284 HydrophobicContact CG1-CE1 4.22Å; V180-F284 HydrophobicContact CG1-CZ 4.35Å
181	V	93.3	Very high	91.4	Very high	74 Å²	74	33.4 Å²	33.4	45%	0.448	18%	0.181	S	C	.	.	I	π-helix	trans	-74	-36.9	-175.9	-169.2	0	0	0	0	110.9	V177 W185 L418	V177-V181 HydrophobicContact CG1-CB 4.34Å; V177-V181 HydrophobicContact CG1-CG2 4.33Å; V177-V181 WeakPolarHBondContact O-CA 3.31Å; V177-V181 VanDerWaalsContact O-CB 3.27Å; V177-V181 WeakPolarHBondContact O-CB 3.34Å; V177-V181 PolarHBondContact O-N 3.48Å; V181-W185 VanDerWaalsContact O-CB 3.24Å; V181-W185 WeakPolarHBondContact O-CB 3.48Å; V181-W185 PolarHBondContact O-N 3.42Å; V181-L418 HydrophobicContact CB-CD2 4.02Å; V181-L418 HydrophobicContact CG1-CD2 3.86Å
182	G	92.4	Very high	91.7	Very high	5 Å²	5	34 Å²	34	5%	0.052	19%	0.192	C	C	.	.	H	α-helix	trans	-70.7	-29.4	177.3	0	0	0	0	0	114.6	V177 F178 N186	V177-G182 PolarHBondContact O-N 3.23Å; V177-G182 VanDerWaalsContact O-N 3.13Å; F178-G182 VanDerWaalsContact O-CA 3.28Å; F178-G182 WeakPolarHBondContact O-CA 3.32Å; F178-G182 PolarHBondContact O-N 2.69Å; G182-N186 WeakPolarHBondContact O-CB 3.28Å; G182-N186 PolarHBondContact O-N 2.75Å; G182-N186 PolarHBondContact O-ND2 2.94Å; G182-N186 VanDerWaalsContact O-ND2 3.09Å; G182-N186 PolarHBondContact O-OD1 3.27Å
183	T	92.9	Very high	92	Very high	1 Å²	1	34 Å²	34	1%	0.006	19%	0.191	C	C	.	.	H	α-helix	trans	-82.7	-38.6	-179.3	57.7	0	0	0	0	111.2	A179 V180 N186 A187 S221 N252 V255	A179-T183 WeakPolarHBondContact O-CB 3.4Å; A179-T183 WeakPolarHBondContact O-CG2 3.35Å; A179-T183 PolarHBondContact O-OG1 3.19Å; V180-T183 PolarHBondContact O-OG1 3.23Å; T183-N186 PolarHBondContact O-N 2.65Å; T183-A187 WeakPolarHBondContact O-CB 3.38Å; T183-A187 PolarHBondContact O-N 3.44Å; T183-S221 WeakPolarHBondContact CA-OG 3.47Å; T183-S221 PolarHBondContact O-OG 3.11Å; T183-N252 HydrophobicContact CG2-CB 3.66Å; T183-N252 WeakPolarHBondContact CG2-OD1 3.35Å; T183-V255 VanDerWaalsContact OG1-CG1 3.27Å; T183-V255 WeakPolarHBondContact OG1-CG1 3.16Å
184	L	93.5	Very high	92	Very high	47 Å²	47	31.5 Å²	31.5	25%	0.246	17%	0.166	C	C	.	.	H	α-helix	trans	-60.4	-46.3	165.5	-67.8	170.2	0	0	0	111	V180 N186 A187 F188 L259	V180-L184 HydrophobicContact CG1-CD1 4.07Å; V180-L184 WeakPolarHBondContact O-CB 3.3Å; V180-L184 WeakPolarHBondContact O-CD1 3.15Å; V180-L184 WeakPolarHBondContact O-CG 3.49Å; V180-L184 PolarHBondContact O-N 2.82Å; V180-L184 VanDerWaalsContact O-N 3.1Å; L184-N186 PolarHBondContact O-N 3.4Å; L184-A187 PolarHBondContact O-N 3.11Å; L184-F188 HydrophobicContact CB-CD2 4.28Å; L184-F188 HydrophobicContact CB-CE2 4.27Å; L184-F188 HydrophobicContact CD2-CE2 4.03Å; L184-F188 WeakPolarHBondContact O-CD2 3.44Å; L184-F188 PolarHBondContact O-N 3.45Å; L184-L259 HydrophobicContact CD2-CD1 4.04Å; L184-L259 HydrophobicContact CD2-CD2 4.1Å
185	W	93.9	Very high	92	Very high	109 Å²	109	33.6 Å²	33.6	41%	0.413	17%	0.174	S	C	.	.	H	α-helix	trans	-55.9	-50.4	175	169.7	-92.2	0	0	0	111.9	V181 A187 F189 S410 L413	V181-W185 VanDerWaalsContact O-CB 3.24Å; V181-W185 WeakPolarHBondContact O-CB 3.48Å; V181-W185 PolarHBondContact O-N 3.42Å; W185-A187 PolarHBondContact O-N 3.35Å; W185-F189 HydrophobicContact CH2-CD2 4.05Å; W185-F189 AromaticContact CZ2-CD2 3.6Å; W185-F189 HydrophobicContact CZ2-CD2 3.6Å; W185-F189 HydrophobicContact CZ2-CE2 4.08Å; W185-F189 HydrophobicContact CZ2-CG 4.4Å; W185-F189 WeakPolarHBondContact O-CB 3.43Å; W185-F189 PolarHBondContact O-N 3.3Å; W185-S410 PolarHBondContact NE1-O 3.29Å; W185-L413 HydrophobicContact CZ2-CB 4.32Å
186	N	92.6	Very high	91.9	Very high	4 Å²	4	36.1 Å²	36.1	2%	0.021	19%	0.194	C	C	.	.	H	α-helix	trans	-60.1	-45.3	178.6	-69.2	-26.2	0	0	0	111.3	G182 T183 L184 I190 S221 S410	G182-N186 WeakPolarHBondContact O-CB 3.28Å; G182-N186 PolarHBondContact O-N 2.75Å; G182-N186 PolarHBondContact O-ND2 2.94Å; G182-N186 VanDerWaalsContact O-ND2 3.09Å; G182-N186 PolarHBondContact O-OD1 3.27Å; T183-N186 PolarHBondContact O-N 2.65Å; L184-N186 PolarHBondContact O-N 3.4Å; N186-I190 VanDerWaalsContact O-CB 3.28Å; N186-I190 WeakPolarHBondContact O-CB 3.26Å; N186-I190 VanDerWaalsContact O-CG1 3.22Å; N186-I190 WeakPolarHBondContact O-CG1 3.25Å; N186-I190 PolarHBondContact O-N 3.2Å; N186-S221 WeakPolarHBondContact CB-OG 3.33Å; N186-S410 PolarHBondContact OD1-OG 3.42Å
187	A	92.8	Very high	91.6	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-64.4	-50.8	-178.3	0	0	0	0	0	112.6	T183 L184 W185 G191 G217 L259	T183-A187 WeakPolarHBondContact O-CB 3.38Å; T183-A187 PolarHBondContact O-N 3.44Å; L184-A187 PolarHBondContact O-N 3.11Å; W185-A187 PolarHBondContact O-N 3.35Å; A187-G191 PolarHBondContact O-N 3.17Å; A187-G217 WeakPolarHBondContact CA-O 3.4Å; A187-L259 HydrophobicContact CB-CD2 3.56Å
188	F	93.5	Very high	91	Very high	107 Å²	107	30.1 Å²	30.1	47%	0.469	16%	0.161	S	C	.	.	H	α-helix	trans	-67.3	-38.4	178.4	-72.2	-63	0	0	0	112.5	L184 G192 L214 F263	L184-F188 HydrophobicContact CB-CD2 4.28Å; L184-F188 HydrophobicContact CB-CE2 4.27Å; L184-F188 HydrophobicContact CD2-CE2 4.03Å; L184-F188 WeakPolarHBondContact O-CD2 3.44Å; L184-F188 PolarHBondContact O-N 3.45Å; F188-G192 WeakPolarHBondContact O-CA 3.4Å; F188-G192 PolarHBondContact O-N 3.03Å; F188-L214 HydrophobicContact CD1-CD2 3.64Å; F188-L214 HydrophobicContact CE1-CD2 4.21Å; F188-F263 HydrophobicContact CE1-CE1 4.49Å; F188-F263 AromaticContact CE1-CZ 3.93Å; F188-F263 HydrophobicContact CE1-CZ 3.93Å; F188-F263 HydrophobicContact CZ-CZ 4.13Å
189	F	94.6	Very high	90.4	Very high	32 Å²	32	36 Å²	36	14%	0.14	19%	0.189	C	C	.	.	H	α-helix	trans	-68	-49.1	178.5	-174.3	-79.9	0	0	0	111.6	W185 M193 L409 S410 L413	W185-F189 HydrophobicContact CH2-CD2 4.05Å; W185-F189 AromaticContact CZ2-CD2 3.6Å; W185-F189 HydrophobicContact CZ2-CD2 3.6Å; W185-F189 HydrophobicContact CZ2-CE2 4.08Å; W185-F189 HydrophobicContact CZ2-CG 4.4Å; W185-F189 WeakPolarHBondContact O-CB 3.43Å; W185-F189 PolarHBondContact O-N 3.3Å; F189-M193 HydrophobicContact CD1-CG 4.12Å; F189-M193 HydrophobicContact CE1-CE 4.26Å; F189-M193 HydrophobicContact CE1-CG 3.92Å; F189-M193 HydrophobicContact CE2-CE 4.02Å; F189-M193 HydrophobicContact CZ-CE 3.66Å; F189-M193 HydrophobicContact CZ-CG 4.22Å; F189-M193 VanDerWaalsContact O-CB 3.25Å; F189-M193 WeakPolarHBondContact O-CB 3.29Å; F189-M193 WeakPolarHBondContact O-CG 3.46Å; F189-M193 PolarHBondContact O-N 3.08Å; F189-L409 HydrophobicContact CZ-CD2 4.26Å; F189-L409 HydrophobicContact CZ-CG 4.43Å; F189-S410 VanDerWaalsContact CD1-CB 3.42Å; F189-S410 WeakPolarHBondContact CD1-OG 3.29Å; F189-L413 HydrophobicContact CE2-CD1 4.05Å; F189-L413 HydrophobicContact CZ-CD1 3.96Å
190	I	92.6	Very high	89.8	Confident	0 Å²	0	40.6 Å²	40.6	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-66.8	-46.6	-179.8	-65.5	170.3	0	0	0	109.9	N186 M193 M194 I220 C407	N186-I190 VanDerWaalsContact O-CB 3.28Å; N186-I190 WeakPolarHBondContact O-CB 3.26Å; N186-I190 VanDerWaalsContact O-CG1 3.22Å; N186-I190 WeakPolarHBondContact O-CG1 3.25Å; N186-I190 PolarHBondContact O-N 3.2Å; I190-M193 PolarHBondContact O-N 3.05Å; I190-M194 HydrophobicContact CG2-CG 4.31Å; I190-M194 VanDerWaalsContact O-CB 3.28Å; I190-M194 WeakPolarHBondContact O-CB 3.23Å; I190-M194 VanDerWaalsContact O-CG 3.22Å; I190-M194 WeakPolarHBondContact O-CG 3.32Å; I190-M194 PolarHBondContact O-N 2.89Å; I190-I220 HydrophobicContact CD1-CG2 3.85Å; I190-C407 HydrophobicContact CD1-CB 4.43Å
191	G	91.4	Very high	88.3	Confident	0 Å²	0	48.4 Å²	48.4	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-64.4	-43.3	179.3	0	0	0	0	0	113.4	A187 M194 F195 C213	A187-G191 PolarHBondContact O-N 3.17Å; G191-M194 PolarHBondContact O-N 3.44Å; G191-F195 WeakPolarHBondContact O-CB 3.35Å; G191-F195 PolarHBondContact O-N 3.02Å; G191-C213 WeakPolarHBondContact CA-O 3.24Å; G191-C213 WeakPolarHBondContact O-CB 3.35Å
192	G	91.9	Very high	86.6	Confident	30 Å²	30	48.6 Å²	48.6	31%	0.309	26%	0.256	S	S	.	.	H	α-helix	trans	-65.4	-41.9	176.3	0	0	0	0	0	113.2	F188 F195 A196	F188-G192 WeakPolarHBondContact O-CA 3.4Å; F188-G192 PolarHBondContact O-N 3.03Å; G192-F195 PolarHBondContact O-N 3.03Å; G192-A196 PolarHBondContact O-N 3.45Å
193	M	91.6	Very high	85.1	Confident	70 Å²	70	48.4 Å²	48.4	35%	0.345	25%	0.254	S	S	.	.	H	α-helix	trans	-69.9	-33.6	176.1	-71.5	-66.5	-153.1	0	0	112.7	F189 I190 A196 V197 F406	F189-M193 HydrophobicContact CD1-CG 4.12Å; F189-M193 HydrophobicContact CE1-CE 4.26Å; F189-M193 HydrophobicContact CE1-CG 3.92Å; F189-M193 HydrophobicContact CE2-CE 4.02Å; F189-M193 HydrophobicContact CZ-CE 3.66Å; F189-M193 HydrophobicContact CZ-CG 4.22Å; F189-M193 VanDerWaalsContact O-CB 3.25Å; F189-M193 WeakPolarHBondContact O-CB 3.29Å; F189-M193 WeakPolarHBondContact O-CG 3.46Å; F189-M193 PolarHBondContact O-N 3.08Å; I190-M193 PolarHBondContact O-N 3.05Å; M193-A196 PolarHBondContact O-N 3.26Å; M193-V197 PolarHBondContact O-N 2.95Å; M193-F406 HydrophobicContact CB-CD2 3.52Å; M193-F406 HydrophobicContact CB-CE2 3.66Å; M193-F406 HydrophobicContact CB-CG 4.05Å; M193-F406 HydrophobicContact CB-CZ 4.29Å; M193-F406 HydrophobicContact CG-CD2 4.46Å
194	M	88.5	Confident	83.3	Confident	0 Å²	0	52.7 Å²	52.7	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-68.8	-41.9	172.9	-75.3	-72.7	92.8	0	0	112.2	I190 G191 A196 V197 C198 F216 F399 F402 T403 F406	I190-M194 HydrophobicContact CG2-CG 4.31Å; I190-M194 VanDerWaalsContact O-CB 3.28Å; I190-M194 WeakPolarHBondContact O-CB 3.23Å; I190-M194 VanDerWaalsContact O-CG 3.22Å; I190-M194 WeakPolarHBondContact O-CG 3.32Å; I190-M194 PolarHBondContact O-N 2.89Å; G191-M194 PolarHBondContact O-N 3.44Å; M194-A196 VanDerWaalsContact C-N 3.32Å; M194-A196 PolarHBondContact O-N 2.64Å; M194-V197 HydrophobicContact CE-CB 4.16Å; M194-V197 HydrophobicContact CE-CG1 4.49Å; M194-V197 HydrophobicContact CE-CG2 4.14Å; M194-V197 PolarHBondContact O-N 3.34Å; M194-V197 VanDerWaalsContact O-N 3.14Å; M194-C198 PolarHBondContact O-N 3.48Å; M194-C198 PolarHBondContact O-SG 2.88Å; M194-F216 HydrophobicContact CG-CD1 4.3Å; M194-F216 HydrophobicContact CG-CE1 4.06Å; M194-F216 HydrophobicContact SD-CE1 4.3Å; M194-F399 HydrophobicContact SD-CD2 4.02Å; M194-F399 HydrophobicContact SD-CE2 3.58Å; M194-F399 VanDerWaalsContact SD-CE2 3.58Å; M194-F399 HydrophobicContact SD-CZ 3.87Å; M194-F402 HydrophobicContact CE-CB 3.55Å; M194-T403 PolarHBondContact SD-OG1 3.42Å; M194-F406 HydrophobicContact CE-CD2 3.4Å; M194-F406 VanDerWaalsContact CE-CD2 3.4Å; M194-F406 HydrophobicContact CE-CE2 3.58Å
195	F	88.4	Confident	81.6	Confident	62 Å²	62	50.7 Å²	50.7	27%	0.272	28%	0.28	S	S	.	.	H	α-helix	trans	-57.3	-45	170	178.9	-107	0	0	0	111.7	G191 G192 V197 C198 Q199 L210 C213	G191-F195 WeakPolarHBondContact O-CB 3.35Å; G191-F195 PolarHBondContact O-N 3.02Å; G192-F195 PolarHBondContact O-N 3.03Å; F195-V197 VanDerWaalsContact C-N 3.28Å; F195-V197 PolarHBondContact O-N 2.98Å; F195-C198 PolarHBondContact O-N 3.07Å; F195-Q199 HydrophobicContact CE1-CG 4.18Å; F195-Q199 HydrophobicContact CE2-CG 4.36Å; F195-Q199 HydrophobicContact CZ-CG 4.06Å; F195-Q199 WeakPolarHBondContact O-CG 3.21Å; F195-Q199 PolarHBondContact O-N 2.83Å; F195-Q199 VanDerWaalsContact O-N 3.12Å; F195-L210 HydrophobicContact CB-CD1 3.75Å; F195-L210 HydrophobicContact CD1-CD1 3.87Å; F195-L210 HydrophobicContact CD2-CB 3.89Å; F195-L210 HydrophobicContact CD2-CD1 4.21Å; F195-L210 HydrophobicContact CE2-CB 4Å; F195-L210 HydrophobicContact CG-CB 4.21Å; F195-L210 HydrophobicContact CG-CD1 3.66Å; F195-L210 HydrophobicContact CZ-CB 4.41Å; F195-C213 HydrophobicContact CB-CB 4.1Å
196	A	88.1	Confident	79.5	Confident	53 Å²	53	48.9 Å²	48.9	44%	0.438	29%	0.288	S	S	.	.	H	α-helix	trans	-60.3	-33.6	176	0	0	0	0	0	113.5	G192 M193 M194	G192-A196 PolarHBondContact O-N 3.45Å; M193-A196 PolarHBondContact O-N 3.26Å; M194-A196 VanDerWaalsContact C-N 3.32Å; M194-A196 PolarHBondContact O-N 2.64Å
197	V	84.6	Confident	78	Confident	7 Å²	7	57.5 Å²	57.5	4%	0.042	33%	0.328	C	S	.	.	H	α-helix	trans	-74.9	-38.4	173.8	168.9	0	0	0	0	112.3	M193 M194 F195 Q199 I200 A203 F402 F406	M193-V197 PolarHBondContact O-N 2.95Å; M194-V197 HydrophobicContact CE-CB 4.16Å; M194-V197 HydrophobicContact CE-CG1 4.49Å; M194-V197 HydrophobicContact CE-CG2 4.14Å; M194-V197 PolarHBondContact O-N 3.34Å; M194-V197 VanDerWaalsContact O-N 3.14Å; F195-V197 VanDerWaalsContact C-N 3.28Å; F195-V197 PolarHBondContact O-N 2.98Å; V197-Q199 PolarHBondContact O-N 2.91Å; V197-I200 WeakPolarHBondContact O-CB 3.2Å; V197-I200 PolarHBondContact O-N 3.1Å; V197-A203 HydrophobicContact CG1-CB 4.24Å; V197-A203 WeakPolarHBondContact O-CB 3.34Å; V197-F402 HydrophobicContact CG1-CB 4.44Å; V197-F402 HydrophobicContact CG1-CD2 3.99Å; V197-F402 HydrophobicContact CG1-CG 4.34Å; V197-F402 HydrophobicContact CG2-CB 4.31Å; V197-F402 HydrophobicContact CG2-CD1 4.28Å; V197-F402 HydrophobicContact CG2-CD2 4.36Å; V197-F402 HydrophobicContact CG2-CG 4.09Å; V197-F406 HydrophobicContact CG2-CE2 3.65Å; V197-F406 HydrophobicContact CG2-CZ 4.07Å
198	C	79.4	Confident	77	Confident	3 Å²	3	58 Å²	58	2%	0.02	33%	0.332	C	S	.	.	H	α-helix	trans	-63.7	-27.1	176.2	-66.4	0	0	0	0	113	M194 F195 I200 A205	M194-C198 PolarHBondContact O-N 3.48Å; M194-C198 PolarHBondContact O-SG 2.88Å; F195-C198 PolarHBondContact O-N 3.07Å; C198-I200 VanDerWaalsContact C-N 3.25Å; C198-I200 PolarHBondContact O-N 2.84Å; C198-A205 HydrophobicContact CB-CB 4.42Å
199	Q	78.9	Confident	76.4	Confident	127 Å²	127	55.6 Å²	55.6	59%	0.593	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.5	-13.1	172.4	-67.4	-62.5	110.4	0	0	113.8	F195 V197	F195-Q199 HydrophobicContact CE1-CG 4.18Å; F195-Q199 HydrophobicContact CE2-CG 4.36Å; F195-Q199 HydrophobicContact CZ-CG 4.06Å; F195-Q199 WeakPolarHBondContact O-CG 3.21Å; F195-Q199 PolarHBondContact O-N 2.83Å; F195-Q199 VanDerWaalsContact O-N 3.12Å; V197-Q199 PolarHBondContact O-N 2.91Å
200	I	78.6	Confident	76	Confident	95 Å²	95	57.9 Å²	57.9	49%	0.487	34%	0.341	S	S	.	.	S	Bend	trans	-83.4	118.4	176.3	-57	174	0	0	0	108.1	V197 C198 A202 A203	V197-I200 WeakPolarHBondContact O-CB 3.2Å; V197-I200 PolarHBondContact O-N 3.1Å; C198-I200 VanDerWaalsContact C-N 3.25Å; C198-I200 PolarHBondContact O-N 2.84Å; I200-A202 HydrophobicContact CG2-CB 4.15Å; I200-A202 PolarHBondContact O-N 3.21Å; I200-A203 WeakPolarHBondContact O-CB 3.13Å; I200-A203 PolarHBondContact O-N 2.92Å
201	E	59.9	Low	75.6	Confident	191 Å²	191	59.5 Å²	59.5	89%	0.893	35%	0.349	S	S	*	.	G	3₁₀ helix	trans	-51.9	-31.3	-175.5	-148.2	168.8	-152.9	0	0	113.5	A203	E201-A203 VanDerWaalsContact C-N 3.27Å; E201-A203 PolarHBondContact O-N 3.38Å
202	A	58.8	Low	75.3	Confident	77 Å²	77	61 Å²	61	64%	0.636	36%	0.36	S	S	*	.	G	3₁₀ helix	trans	-67.8	-14.3	176.1	0	0	0	0	0	115.4	I200 I398	I200-A202 HydrophobicContact CG2-CB 4.15Å; I200-A202 PolarHBondContact O-N 3.21Å; A202-I398 VanDerWaalsContact O-CD1 3.3Å; A202-I398 WeakPolarHBondContact O-CD1 3.45Å
203	A	59.7	Low	75.2	Confident	1 Å²	1	59.6 Å²	59.6	1%	0.008	35%	0.346	C	S	.	.	G	3₁₀ helix	trans	-84.3	-7.4	-177	0	0	0	0	0	114.1	V197 I200 E201 A205 N396 I398	V197-A203 HydrophobicContact CG1-CB 4.24Å; V197-A203 WeakPolarHBondContact O-CB 3.34Å; I200-A203 WeakPolarHBondContact O-CB 3.13Å; I200-A203 PolarHBondContact O-N 2.92Å; E201-A203 VanDerWaalsContact C-N 3.27Å; E201-A203 PolarHBondContact O-N 3.38Å; A203-A205 PolarHBondContact O-N 2.89Å; A203-N396 PolarHBondContact O-ND2 3.34Å; A203-I398 HydrophobicContact CB-CG2 4.4Å
204	A	55.2	Low	75.1	Confident	91 Å²	91	57.4 Å²	57.4	75%	0.752	34%	0.335	S	S	*	.	S	Bend	trans	53.7	22.8	-178.9	0	0	0	0	0	115.3
205	A	58.2	Low	75.1	Confident	6 Å²	6	58 Å²	58	5%	0.05	34%	0.338	C	S	.	.			trans	-120.7	31.4	-174.5	0	0	0	0	0	112.7	C198 A203 H207 V208 M467	C198-A205 HydrophobicContact CB-CB 4.42Å; A203-A205 PolarHBondContact O-N 2.89Å; A205-H207 PolarHBondContact O-N 3.41Å; A205-V208 HydrophobicContact CB-CG2 4.36Å; A205-V208 PolarHBondContact O-N 3.46Å; A205-M467 HydrophobicContact CB-CE 4.36Å
206	A	50.2	Low	75.2	Confident	70 Å²	70	55 Å²	55	58%	0.579	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.7	6.9	-164.7	0	0	0	0	0	116.9
207	H	61.5	Low	75.3	Confident	186 Å²	186	52.5 Å²	52.5	86%	0.861	30%	0.304	S	S	*	.	T	Hydrogen-bonded Turn	trans	-126.1	13.9	-178.4	-66.1	-56.2	0	0	0	114.1	A205	A205-H207 PolarHBondContact O-N 3.41Å
208	V	71.1	Confident	75.6	Confident	11 Å²	11	52.2 Å²	52.2	7%	0.067	30%	0.302	C	S	.	.			trans	-84.6	121.6	177.9	-174.3	0	0	0	0	110.9	A205 C213 T464 F468	A205-V208 HydrophobicContact CB-CG2 4.36Å; A205-V208 PolarHBondContact O-N 3.46Å; V208-C213 VanDerWaalsContact CG1-SG 3.52Å; V208-T464 HydrophobicContact CG1-CG2 4.2Å; V208-T464 HydrophobicContact CG2-CG2 3.82Å; V208-F468 HydrophobicContact CG1-CE1 4.28Å; V208-F468 HydrophobicContact CG1-CZ 3.73Å
209	S	82.1	Confident	76.2	Confident	56 Å²	56	52 Å²	52	39%	0.392	30%	0.301	S	S	.	.			trans	-67.5	151.4	177.9	82.7	0	0	0	0	112.5	L211 S212 C213	S209-L211 PolarHBondContact O-N 2.92Å; S209-S212 WeakPolarHBondContact O-CB 2.95Å; S209-S212 PolarHBondContact O-N 3.05Å; S209-S212 VanDerWaalsContact O-N 3.15Å; S209-S212 PolarHBondContact OG-N 3.32Å; S209-S212 PolarHBondContact OG-OG 2.92Å; S209-C213 PolarHBondContact O-N 2.94Å; S209-C213 VanDerWaalsContact O-N 3.11Å
210	L	84.6	Confident	76.7	Confident	79 Å²	79	46.2 Å²	46.2	41%	0.414	27%	0.274	S	S	.	.	H	α-helix	trans	-53.9	-39.5	173.5	173.6	61.3	0	0	0	111.7	F195 C213 L214	F195-L210 HydrophobicContact CB-CD1 3.75Å; F195-L210 HydrophobicContact CD1-CD1 3.87Å; F195-L210 HydrophobicContact CD2-CB 3.89Å; F195-L210 HydrophobicContact CD2-CD1 4.21Å; F195-L210 HydrophobicContact CE2-CB 4Å; F195-L210 HydrophobicContact CG-CB 4.21Å; F195-L210 HydrophobicContact CG-CD1 3.66Å; F195-L210 HydrophobicContact CZ-CB 4.41Å; L210-C213 WeakPolarHBondContact O-CB 3.32Å; L210-C213 PolarHBondContact O-N 3.44Å; L210-L214 HydrophobicContact CD1-CD1 4.4Å; L210-L214 HydrophobicContact CD1-CG 4.31Å; L210-L214 HydrophobicContact CG-CD1 4.16Å; L210-L214 HydrophobicContact CG-CG 4.5Å; L210-L214 WeakPolarHBondContact O-CG 3.44Å; L210-L214 PolarHBondContact O-N 3.34Å
211	L	85.1	Confident	77.3	Confident	34 Å²	34	41.7 Å²	41.7	18%	0.178	25%	0.251	C	S	.	.	H	α-helix	trans	-68.7	-39.4	-179.5	-170.4	70.7	0	0	0	112	S209 C213 L214 L215 F263 F266 S267	S209-L211 PolarHBondContact O-N 2.92Å; L211-C213 VanDerWaalsContact C-N 3.26Å; L211-C213 PolarHBondContact O-N 3.09Å; L211-L214 PolarHBondContact O-N 2.9Å; L211-L214 VanDerWaalsContact O-N 3.13Å; L211-L215 WeakPolarHBondContact O-CB 3.16Å; L211-L215 PolarHBondContact O-N 3.36Å; L211-F263 HydrophobicContact CD1-CB 4.3Å; L211-F263 HydrophobicContact CD1-CD1 3.91Å; L211-F263 HydrophobicContact CD1-CG 4.38Å; L211-F266 HydrophobicContact CD1-CB 4.11Å; L211-F266 HydrophobicContact CD2-CB 3.84Å; L211-F266 WeakPolarHBondContact CD2-O 3.25Å; L211-S267 VanDerWaalsContact CD2-N 3.34Å
212	S	85.4	Confident	78.7	Confident	33 Å²	33	32.6 Å²	32.6	23%	0.231	21%	0.208	C	C	.	.	H	α-helix	trans	-59.6	-38.6	171.7	-51.5	0	0	0	0	111.5	S209 F216	S209-S212 WeakPolarHBondContact O-CB 2.95Å; S209-S212 PolarHBondContact O-N 3.05Å; S209-S212 VanDerWaalsContact O-N 3.15Å; S209-S212 PolarHBondContact OG-N 3.32Å; S209-S212 PolarHBondContact OG-OG 2.92Å; S212-F216 WeakPolarHBondContact O-CB 3.28Å; S212-F216 PolarHBondContact O-N 3.4Å
213	C	88.3	Confident	79.9	Confident	0 Å²	0	29 Å²	29	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-68.5	-36.8	173.7	-66.2	0	0	0	0	112.9	G191 F195 V208 S209 L210 L211 F216 G217	G191-C213 WeakPolarHBondContact CA-O 3.24Å; G191-C213 WeakPolarHBondContact O-CB 3.35Å; F195-C213 HydrophobicContact CB-CB 4.1Å; V208-C213 VanDerWaalsContact CG1-SG 3.52Å; S209-C213 PolarHBondContact O-N 2.94Å; S209-C213 VanDerWaalsContact O-N 3.11Å; L210-C213 WeakPolarHBondContact O-CB 3.32Å; L210-C213 PolarHBondContact O-N 3.44Å; L211-C213 VanDerWaalsContact C-N 3.26Å; L211-C213 PolarHBondContact O-N 3.09Å; C213-F216 PolarHBondContact O-N 3.41Å; C213-G217 PolarHBondContact O-N 2.86Å
214	L	89.8	Confident	81	Confident	24 Å²	24	30.3 Å²	30.3	13%	0.126	19%	0.185	C	C	.	.	H	α-helix	trans	-69.7	-38.9	175.2	-72.8	173.6	0	0	0	112.3	F188 L210 L211 G217 S218 F263	F188-L214 HydrophobicContact CD1-CD2 3.64Å; F188-L214 HydrophobicContact CE1-CD2 4.21Å; L210-L214 HydrophobicContact CD1-CD1 4.4Å; L210-L214 HydrophobicContact CD1-CG 4.31Å; L210-L214 HydrophobicContact CG-CD1 4.16Å; L210-L214 HydrophobicContact CG-CG 4.5Å; L210-L214 WeakPolarHBondContact O-CG 3.44Å; L210-L214 PolarHBondContact O-N 3.34Å; L211-L214 PolarHBondContact O-N 2.9Å; L211-L214 VanDerWaalsContact O-N 3.13Å; L214-G217 PolarHBondContact O-N 2.89Å; L214-S218 PolarHBondContact O-N 3.16Å; L214-F263 HydrophobicContact CB-CD2 4.23Å; L214-F263 HydrophobicContact CB-CE1 4.42Å; L214-F263 HydrophobicContact CB-CE2 3.98Å; L214-F263 HydrophobicContact CB-CZ 4.09Å; L214-F263 WeakPolarHBondContact O-CD2 3.15Å; L214-F263 WeakPolarHBondContact O-CE2 3.42Å
215	L	89.4	Confident	82	Confident	12 Å²	12	26.4 Å²	26.4	6%	0.063	15%	0.153	C	C	.	.	H	α-helix	trans	-61.1	-46.4	171.4	-175	152.3	0	0	0	110.5	L211 G217 S218 I219 Y260 F263 E264 I455	L211-L215 WeakPolarHBondContact O-CB 3.16Å; L211-L215 PolarHBondContact O-N 3.36Å; L215-G217 PolarHBondContact O-N 2.88Å; L215-S218 WeakPolarHBondContact O-CB 3.37Å; L215-S218 PolarHBondContact O-N 3.18Å; L215-I219 HydrophobicContact CD2-CD1 3.64Å; L215-I219 HydrophobicContact CD2-CG1 4.42Å; L215-I219 WeakPolarHBondContact O-CG1 3.48Å; L215-I219 PolarHBondContact O-N 2.97Å; L215-Y260 HydrophobicContact CD1-CE2 4.39Å; L215-Y260 HydrophobicContact CD2-CD2 4.28Å; L215-Y260 HydrophobicContact CD2-CE2 3.99Å; L215-Y260 HydrophobicContact CG-CD2 4.25Å; L215-Y260 HydrophobicContact CG-CE2 4.25Å; L215-F263 HydrophobicContact CB-CB 4.02Å; L215-F263 HydrophobicContact CD1-CB 4.42Å; L215-F263 HydrophobicContact CG-CB 4.42Å; L215-E264 HydrophobicContact CD1-CB 4.24Å; L215-I455 HydrophobicContact CD2-CD1 4.03Å; L215-I455 HydrophobicContact CD2-CG1 4.02Å
216	F	89.3	Confident	82.8	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-59.8	-42.9	172.4	177.3	-107.1	0	0	0	112.8	M194 S212 C213 S218 I219 I220 F399 T403 F468 A471 I472	M194-F216 HydrophobicContact CG-CD1 4.3Å; M194-F216 HydrophobicContact CG-CE1 4.06Å; M194-F216 HydrophobicContact SD-CE1 4.3Å; S212-F216 WeakPolarHBondContact O-CB 3.28Å; S212-F216 PolarHBondContact O-N 3.4Å; C213-F216 PolarHBondContact O-N 3.41Å; F216-S218 VanDerWaalsContact C-N 3.35Å; F216-S218 PolarHBondContact O-N 3.05Å; F216-I219 PolarHBondContact O-N 3.2Å; F216-I220 HydrophobicContact CD1-CD1 4.2Å; F216-I220 HydrophobicContact CD2-CD1 4.3Å; F216-I220 HydrophobicContact CE1-CD1 3.6Å; F216-I220 HydrophobicContact CE2-CD1 3.72Å; F216-I220 HydrophobicContact CE2-CG1 4.47Å; F216-I220 HydrophobicContact CZ-CD1 3.34Å; F216-I220 HydrophobicContact CZ-CG1 4.49Å; F216-I220 PolarHBondContact O-N 2.95Å; F216-F399 HydrophobicContact CD1-CZ 4.21Å; F216-F399 AromaticContact CE1-CE1 3.97Å; F216-F399 HydrophobicContact CE1-CE1 3.97Å; F216-F399 AromaticContact CE1-CZ 3.67Å; F216-F399 HydrophobicContact CE1-CZ 3.67Å; F216-F399 HydrophobicContact CE2-CE1 4.23Å; F216-F399 HydrophobicContact CE2-CZ 4.45Å; F216-F399 AromaticContact CZ-CE1 3.61Å; F216-F399 HydrophobicContact CZ-CE1 3.61Å; F216-F399 AromaticContact CZ-CZ 3.79Å; F216-F399 HydrophobicContact CZ-CZ 3.79Å; F216-T403 HydrophobicContact CE1-CG2 3.82Å; F216-T403 HydrophobicContact CZ-CG2 3.74Å; F216-F468 HydrophobicContact CB-CD2 4.19Å; F216-F468 HydrophobicContact CB-CE1 4.47Å; F216-F468 HydrophobicContact CB-CE2 4.01Å; F216-F468 HydrophobicContact CB-CG 4.49Å; F216-F468 HydrophobicContact CB-CZ 4.15Å; F216-F468 HydrophobicContact CD2-CB 3.74Å; F216-F468 AromaticContact CD2-CD1 3.81Å; F216-F468 HydrophobicContact CD2-CD1 3.81Å; F216-F468 HydrophobicContact CD2-CD2 4.04Å; F216-F468 HydrophobicContact CD2-CE1 4.4Å; F216-F468 AromaticContact CD2-CG 3.6Å; F216-F468 HydrophobicContact CD2-CG 3.6Å; F216-F468 HydrophobicContact CE2-CB 3.87Å; F216-F468 HydrophobicContact CE2-CD1 4.02Å; F216-F468 HydrophobicContact CE2-CG 4.03Å; F216-F468 HydrophobicContact CG-CD1 4.19Å; F216-F468 HydrophobicContact CG-CD2 4.43Å; F216-F468 HydrophobicContact CG-CE1 4.33Å; F216-F468 HydrophobicContact CG-CG 4.24Å; F216-F468 HydrophobicContact CG-CZ 4.49Å; F216-A471 HydrophobicContact CE2-CB 4.14Å; F216-A471 HydrophobicContact CZ-CB 3.83Å; F216-I472 HydrophobicContact CD2-CD1 4.21Å; F216-I472 HydrophobicContact CD2-CG1 4.34Å; F216-I472 HydrophobicContact CE2-CD1 4.15Å; F216-I472 HydrophobicContact CE2-CG1 3.86Å
217	G	90.9	Very high	84.1	Confident	0 Å²	0	26.2 Å²	26.2	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-61.4	-40	174.1	0	0	0	0	0	112.9	A187 C213 L214 L215 S221	A187-G217 WeakPolarHBondContact CA-O 3.4Å; C213-G217 PolarHBondContact O-N 2.86Å; L214-G217 PolarHBondContact O-N 2.89Å; L215-G217 PolarHBondContact O-N 2.88Å; G217-S221 PolarHBondContact O-N 3.43Å; G217-S221 VanDerWaalsContact O-N 3.08Å
218	S	91.9	Very high	85	Confident	0 Å²	0	17.3 Å²	17.3	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-58.8	-55.2	172.4	179.2	0	0	0	0	110.8	L214 L215 F216 I220 S221 T256 L259 Y260	L214-S218 PolarHBondContact O-N 3.16Å; L215-S218 WeakPolarHBondContact O-CB 3.37Å; L215-S218 PolarHBondContact O-N 3.18Å; F216-S218 VanDerWaalsContact C-N 3.35Å; F216-S218 PolarHBondContact O-N 3.05Å; S218-I220 VanDerWaalsContact C-N 3.31Å; S218-I220 PolarHBondContact O-N 3.38Å; S218-S221 WeakPolarHBondContact O-CA 3.37Å; S218-S221 WeakPolarHBondContact O-CB 3.42Å; S218-S221 PolarHBondContact O-N 3.4Å; S218-T256 WeakPolarHBondContact O-CG2 3.36Å; S218-T256 PolarHBondContact OG-O 2.84Å; S218-L259 WeakPolarHBondContact OG-CB 3.31Å; S218-L259 WeakPolarHBondContact OG-CG 3.31Å; S218-Y260 PolarHBondContact OG-N 3.31Å
219	I	90.6	Very high	85.5	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-54.2	-47.4	-179.8	-67.1	173.6	0	0	0	111.7	L215 F216 S221 Y260 A448 L451 I455 I472	L215-I219 HydrophobicContact CD2-CD1 3.64Å; L215-I219 HydrophobicContact CD2-CG1 4.42Å; L215-I219 WeakPolarHBondContact O-CG1 3.48Å; L215-I219 PolarHBondContact O-N 2.97Å; F216-I219 PolarHBondContact O-N 3.2Å; I219-S221 PolarHBondContact O-N 3.15Å; I219-Y260 HydrophobicContact CD1-CD2 3.87Å; I219-Y260 HydrophobicContact CD1-CE2 3.88Å; I219-Y260 HydrophobicContact CG1-CD2 3.69Å; I219-Y260 HydrophobicContact CG1-CE2 4.23Å; I219-A448 HydrophobicContact CG2-CB 4.1Å; I219-A448 WeakPolarHBondContact CG2-O 3.24Å; I219-A448 WeakPolarHBondContact O-CB 3.22Å; I219-L451 HydrophobicContact CD1-CB 4.26Å; I219-L451 HydrophobicContact CG1-CB 3.88Å; I219-L451 HydrophobicContact CG2-CB 4.05Å; I219-I455 HydrophobicContact CD1-CD1 3.59Å; I219-I455 HydrophobicContact CD1-CG1 3.77Å; I219-I472 HydrophobicContact CG2-CD1 3.7Å; I219-I472 HydrophobicContact CG2-CG1 4.33Å
220	I	89.9	Confident	85.3	Confident	4 Å²	4	17.4 Å²	17.4	2%	0.021	11%	0.106	C	C	.	.	H	α-helix	trans	-68.1	-21.5	178.6	-71	-177.3	0	0	0	111.7	I190 F216 S218 A222 T403 R444 I472	I190-I220 HydrophobicContact CD1-CG2 3.85Å; F216-I220 HydrophobicContact CD1-CD1 4.2Å; F216-I220 HydrophobicContact CD2-CD1 4.3Å; F216-I220 HydrophobicContact CE1-CD1 3.6Å; F216-I220 HydrophobicContact CE2-CD1 3.72Å; F216-I220 HydrophobicContact CE2-CG1 4.47Å; F216-I220 HydrophobicContact CZ-CD1 3.34Å; F216-I220 HydrophobicContact CZ-CG1 4.49Å; F216-I220 PolarHBondContact O-N 2.95Å; S218-I220 VanDerWaalsContact C-N 3.31Å; S218-I220 PolarHBondContact O-N 3.38Å; I220-A222 VanDerWaalsContact C-N 3.27Å; I220-A222 PolarHBondContact O-N 2.88Å; I220-T403 HydrophobicContact CD1-CG2 3.58Å; I220-R444 WeakPolarHBondContact O-CD 3.26Å; I220-R444 PolarHBondContact O-NE 2.73Å; I220-R444 VanDerWaalsContact O-NE 3.12Å; I220-R444 PolarHBondContact O-NH1 2.91Å; I220-R444 PolarHBondContact O-NH2 3.4Å; I220-I472 HydrophobicContact CD1-CG1 4.23Å; I220-I472 HydrophobicContact CG1-CG1 3.99Å
221	S	90.7	Very high	84.9	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-62.4	-28.1	-177	-157.2	0	0	0	0	114.4	T183 N186 G217 S218 I219 N252 R444	T183-S221 WeakPolarHBondContact CA-OG 3.47Å; T183-S221 PolarHBondContact O-OG 3.11Å; N186-S221 WeakPolarHBondContact CB-OG 3.33Å; G217-S221 PolarHBondContact O-N 3.43Å; G217-S221 VanDerWaalsContact O-N 3.08Å; S218-S221 WeakPolarHBondContact O-CA 3.37Å; S218-S221 WeakPolarHBondContact O-CB 3.42Å; S218-S221 PolarHBondContact O-N 3.4Å; I219-S221 PolarHBondContact O-N 3.15Å; S221-N252 PolarHBondContact O-ND2 3.47Å; S221-R444 PolarHBondContact O-NH1 3.28Å
222	A	89.4	Confident	84.6	Confident	0 Å²	0	13 Å²	13	0%	0	8%	0.084	C	C	.	.			trans	-53.8	141.5	175	0	0	0	0	0	112.1	I220 T256 R444 A448	I220-A222 VanDerWaalsContact C-N 3.27Å; I220-A222 PolarHBondContact O-N 2.88Å; A222-T256 HydrophobicContact CB-CG2 3.96Å; A222-T256 PolarHBondContact N-OG1 2.9Å; A222-R444 WeakPolarHBondContact O-CD 3.41Å; A222-R444 PolarHBondContact O-NH1 3.36Å; A222-A448 HydrophobicContact CB-CB 4.46Å
223	V	85	Confident	84.1	Confident	1 Å²	1	18 Å²	18	1%	0.006	10%	0.103	C	C	.	.			trans	-135.3	124.8	-175.8	170.3	0	0	0	0	108.5	S249 N252 L443	V223-S249 WeakPolarHBondContact O-CB 3.4Å; V223-S249 PolarHBondContact O-OG 3.41Å; V223-N252 WeakPolarHBondContact CB-ND2 3.13Å; V223-N252 PolarHBondContact N-ND2 3.26Å; V223-N252 VanDerWaalsContact N-ND2 3.11Å; V223-L443 CarbonylContact C-O 3.55Å; V223-L443 VanDerWaalsContact CA-O 3.3Å; V223-L443 WeakPolarHBondContact CA-O 3.46Å
224	D	82.6	Confident	83.4	Confident	29 Å²	29	23.2 Å²	23.2	16%	0.155	13%	0.127	C	C	.	.	B	Isolated β-bridge	trans	-103	124.5	176.8	179	-12.4	0	0	0	109.5	V226 L443	D224-V226 VanDerWaalsContact OD1-CB 3.31Å; D224-V226 WeakPolarHBondContact OD1-CB 3.4Å; D224-V226 WeakPolarHBondContact OD1-CG2 3.3Å; D224-V226 PolarHBondContact OD1-N 3.08Å; D224-L443 PolarHBondContact N-O 2.96Å; D224-L443 WeakPolarHBondContact O-CB 3.33Å
225	P	75.7	Confident	82.6	Confident	10 Å²	10	23.6 Å²	23.6	7%	0.065	13%	0.129	C	C	.	.			trans	-99.1	-1.7	-176.3	42.1	-36.9	0	0	0	112.5	A227 V228 L229 V245 S249	P225-A227 PolarHBondContact O-N 3.02Å; P225-V228 CarbonylContact O-C 3.5Å; P225-V228 WeakPolarHBondContact O-CA 3.43Å; P225-V228 WeakPolarHBondContact O-CB 3.23Å; P225-V228 PolarHBondContact O-N 2.81Å; P225-L229 HydrophobicContact CB-CD1 3.78Å; P225-L229 HydrophobicContact CB-CG 3.92Å; P225-L229 HydrophobicContact CG-CD1 3.56Å; P225-L229 HydrophobicContact CG-CG 4.26Å; P225-L229 WeakPolarHBondContact O-CG 3.36Å; P225-L229 PolarHBondContact O-N 3.07Å; P225-V245 HydrophobicContact CB-CG1 3.87Å; P225-S249 WeakPolarHBondContact CB-OG 3.42Å; P225-S249 VanDerWaalsContact CD-CB 3.45Å; P225-S249 VanDerWaalsContact CG-CB 3.5Å; P225-S249 WeakPolarHBondContact CG-OG 3.45Å
226	V	75.3	Confident	81.6	Confident	58 Å²	58	30.1 Å²	30.1	35%	0.352	16%	0.159	S	C	.	.	H	α-helix	trans	-56.8	-51	-160.6	169.1	0	0	0	0	112.4	D224 V228 L229 A230 E377	D224-V226 VanDerWaalsContact OD1-CB 3.31Å; D224-V226 WeakPolarHBondContact OD1-CB 3.4Å; D224-V226 WeakPolarHBondContact OD1-CG2 3.3Å; D224-V226 PolarHBondContact OD1-N 3.08Å; V226-V228 PolarHBondContact O-N 2.92Å; V226-L229 PolarHBondContact O-N 2.95Å; V226-A230 PolarHBondContact O-N 3.08Å; V226-E377 WeakPolarHBondContact CG1-OE1 3.34Å
227	A	78.1	Confident	80.7	Confident	13 Å²	13	31.6 Å²	31.6	11%	0.107	17%	0.167	C	C	.	.	H	α-helix	trans	-63.5	-27.3	177.8	0	0	0	0	0	113.2	P116 P225 V231 L443	P116-A227 HydrophobicContact CB-CB 3.91Å; P116-A227 HydrophobicContact CG-CB 4.4Å; P225-A227 PolarHBondContact O-N 3.02Å; A227-V231 WeakPolarHBondContact O-CG2 3.15Å; A227-L443 HydrophobicContact CB-CD1 3.79Å
228	V	78.9	Confident	79.9	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-79.7	-40.9	179	-176.9	0	0	0	0	110.9	P225 V226 V231 F232 G441 L443 I487	P225-V228 CarbonylContact O-C 3.5Å; P225-V228 WeakPolarHBondContact O-CA 3.43Å; P225-V228 WeakPolarHBondContact O-CB 3.23Å; P225-V228 PolarHBondContact O-N 2.81Å; V226-V228 PolarHBondContact O-N 2.92Å; V228-V231 PolarHBondContact O-N 2.92Å; V228-F232 HydrophobicContact CG1-CD1 4Å; V228-F232 HydrophobicContact CG1-CD2 4.46Å; V228-F232 HydrophobicContact CG1-CE1 3.4Å; V228-F232 VanDerWaalsContact CG1-CE1 3.4Å; V228-F232 HydrophobicContact CG1-CE2 3.92Å; V228-F232 HydrophobicContact CG1-CG 4.5Å; V228-F232 HydrophobicContact CG1-CZ 3.34Å; V228-F232 WeakPolarHBondContact O-CD1 3.35Å; V228-F232 VanDerWaalsContact O-CG 3.3Å; V228-F232 WeakPolarHBondContact O-CG 3.23Å; V228-F232 PolarHBondContact O-N 3.21Å; V228-G441 WeakPolarHBondContact CG2-O 3.5Å; V228-L443 HydrophobicContact CG2-CD1 3.77Å; V228-L443 HydrophobicContact CG2-CG 3.94Å; V228-I487 HydrophobicContact CG1-CD1 4.26Å; V228-I487 HydrophobicContact CG1-CG1 4.13Å; V228-I487 HydrophobicContact CG2-CD1 4.49Å; V228-I487 HydrophobicContact CG2-CG1 4.16Å
229	L	82.3	Confident	79.2	Confident	19 Å²	19	42.3 Å²	42.3	10%	0.099	22%	0.219	C	C	.	.	H	α-helix	trans	-66.9	-40.8	177.9	-66.9	172.6	0	0	0	111.8	P225 V226 V231 F232 E233 V245 F246	P225-L229 HydrophobicContact CB-CD1 3.78Å; P225-L229 HydrophobicContact CB-CG 3.92Å; P225-L229 HydrophobicContact CG-CD1 3.56Å; P225-L229 HydrophobicContact CG-CG 4.26Å; P225-L229 WeakPolarHBondContact O-CG 3.36Å; P225-L229 PolarHBondContact O-N 3.07Å; V226-L229 PolarHBondContact O-N 2.95Å; L229-V231 VanDerWaalsContact C-N 3.3Å; L229-V231 PolarHBondContact O-N 3.44Å; L229-F232 PolarHBondContact O-N 3.21Å; L229-F232 VanDerWaalsContact O-N 3.11Å; L229-E233 WeakPolarHBondContact O-CB 3.39Å; L229-E233 PolarHBondContact O-N 2.68Å; L229-V245 HydrophobicContact CD2-CG1 4.4Å; L229-F246 HydrophobicContact CD1-CB 3.96Å; L229-F246 HydrophobicContact CD1-CD2 3.54Å; L229-F246 HydrophobicContact CD1-CE2 4.46Å; L229-F246 HydrophobicContact CD1-CG 4.17Å; L229-F246 HydrophobicContact CD2-CB 4.05Å
230	A	77.1	Confident	78.8	Confident	50 Å²	50	44.9 Å²	44.9	41%	0.413	23%	0.232	S	C	.	.	H	α-helix	trans	-55.3	-46.4	173	0	0	0	0	0	111.6	V226 F232 E233 E234	V226-A230 PolarHBondContact O-N 3.08Å; A230-F232 PolarHBondContact O-N 2.77Å; A230-E233 PolarHBondContact O-N 3.4Å; A230-E234 PolarHBondContact O-N 3.39Å; A230-E234 VanDerWaalsContact O-N 3.09Å
231	V	78.1	Confident	78.5	Confident	17 Å²	17	45 Å²	45	10%	0.103	23%	0.233	C	C	.	.	H	α-helix	trans	-66.4	-35.9	176.3	167.9	0	0	0	0	112.3	A227 V228 L229 I235 I487 R488	A227-V231 WeakPolarHBondContact O-CG2 3.15Å; V228-V231 PolarHBondContact O-N 2.92Å; L229-V231 VanDerWaalsContact C-N 3.3Å; L229-V231 PolarHBondContact O-N 3.44Å; V231-I235 HydrophobicContact CG1-CD1 3.65Å; V231-I235 WeakPolarHBondContact O-CB 3.36Å; V231-I235 VanDerWaalsContact O-CG1 3.3Å; V231-I235 WeakPolarHBondContact O-CG1 3.49Å; V231-I235 PolarHBondContact O-N 2.97Å; V231-I235 VanDerWaalsContact O-N 3.08Å; V231-I487 HydrophobicContact CG2-CG2 4.13Å; V231-R488 HydrophobicContact CG1-CB 4.12Å; V231-R488 HydrophobicContact CG1-CG 4.35Å; V231-R488 HydrophobicContact CG2-CB 4.09Å
232	F	78.2	Confident	78.3	Confident	4 Å²	4	47.7 Å²	47.7	2%	0.018	25%	0.246	C	C	.	.	H	α-helix	trans	-70.4	-34.9	176.6	-72.4	9.9	0	0	0	112.6	V228 L229 A230 H236 I237 L241 V245 I437 V491	V228-F232 HydrophobicContact CG1-CD1 4Å; V228-F232 HydrophobicContact CG1-CD2 4.46Å; V228-F232 HydrophobicContact CG1-CE1 3.4Å; V228-F232 VanDerWaalsContact CG1-CE1 3.4Å; V228-F232 HydrophobicContact CG1-CE2 3.92Å; V228-F232 HydrophobicContact CG1-CG 4.5Å; V228-F232 HydrophobicContact CG1-CZ 3.34Å; V228-F232 WeakPolarHBondContact O-CD1 3.35Å; V228-F232 VanDerWaalsContact O-CG 3.3Å; V228-F232 WeakPolarHBondContact O-CG 3.23Å; V228-F232 PolarHBondContact O-N 3.21Å; L229-F232 PolarHBondContact O-N 3.21Å; L229-F232 VanDerWaalsContact O-N 3.11Å; A230-F232 PolarHBondContact O-N 2.77Å; F232-H236 PolarHBondContact O-N 2.91Å; F232-H236 VanDerWaalsContact O-N 3.07Å; F232-I237 HydrophobicContact CB-CD1 4.1Å; F232-I237 HydrophobicContact CD1-CD1 3.36Å; F232-I237 HydrophobicContact CD2-CD1 4.49Å; F232-I237 HydrophobicContact CE1-CD1 3.87Å; F232-I237 HydrophobicContact CG-CD1 3.73Å; F232-I237 PolarHBondContact O-N 3.32Å; F232-L241 HydrophobicContact CE2-CD2 4.23Å; F232-L241 HydrophobicContact CE2-CG 4.29Å; F232-L241 HydrophobicContact CZ-CD2 4.44Å; F232-V245 HydrophobicContact CE2-CG2 4.18Å; F232-I437 HydrophobicContact CE1-CG2 3.86Å; F232-I437 HydrophobicContact CE2-CG2 4.38Å; F232-I437 HydrophobicContact CZ-CG2 3.38Å; F232-V491 HydrophobicContact CE1-CG2 3.95Å
233	E	74.4	Confident	78.2	Confident	137 Å²	137	47.9 Å²	47.9	64%	0.64	25%	0.246	S	C	*	.	H	α-helix	trans	-66.3	-44.8	175	-170.4	168.2	-167.7	0	0	110.4	L229 A230 H236	L229-E233 WeakPolarHBondContact O-CB 3.39Å; L229-E233 PolarHBondContact O-N 2.68Å; A230-E233 PolarHBondContact O-N 3.4Å; E233-H236 PolarHBondContact O-CE1 2.92Å; E233-H236 VanDerWaalsContact O-CE1 3.3Å; E233-H236 PolarHBondContact O-N 2.85Å; E233-H236 PolarHBondContact O-ND1 3.27Å
234	E	74.5	Confident	78.3	Confident	109 Å²	109	48 Å²	48	51%	0.509	25%	0.247	S	C	.	.	H	α-helix	trans	-61.6	-43.2	174.3	-74.8	-172.8	-150.5	0	0	113.5	A230 H236 R488	A230-E234 PolarHBondContact O-N 3.39Å; A230-E234 VanDerWaalsContact O-N 3.09Å; E234-H236 VanDerWaalsContact C-N 3.28Å; E234-H236 PolarHBondContact O-N 3.48Å; E234-R488 IonicContact OE1-NH1 3.69Å; E234-R488 IonicContact OE2-CZ 2.69Å; E234-R488 IonicContact OE2-NH1 3.12Å; E234-R488 PolarHBondContact OE2-NH1 3.29Å; E234-R488 IonicContact OE2-NH2 3.93Å; E234-R488 PolarHBondContact OE2-NH2 2.95Å
235	I	72.7	Confident	78.6	Confident	32 Å²	32	46.8 Å²	46.8	16%	0.164	24%	0.241	C	C	.	.	H	α-helix	trans	-84.5	-5.7	-174.6	-61.9	170.8	0	0	0	112	V231 I237 V491 E492 A495 K498	V231-I235 HydrophobicContact CG1-CD1 3.65Å; V231-I235 WeakPolarHBondContact O-CB 3.36Å; V231-I235 VanDerWaalsContact O-CG1 3.3Å; V231-I235 WeakPolarHBondContact O-CG1 3.49Å; V231-I235 PolarHBondContact O-N 2.97Å; V231-I235 VanDerWaalsContact O-N 3.08Å; I235-I237 HydrophobicContact CB-CD1 4.35Å; I235-I237 HydrophobicContact CB-CG1 4.04Å; I235-I237 HydrophobicContact CG2-CD1 4.25Å; I235-I237 HydrophobicContact CG2-CG1 3.81Å; I235-I237 PolarHBondContact O-N 2.67Å; I235-V491 HydrophobicContact CD1-CB 4.21Å; I235-V491 HydrophobicContact CD1-CG1 3.62Å; I235-V491 HydrophobicContact CG2-CG1 4.37Å; I235-E492 HydrophobicContact CD1-CG 3.69Å; I235-E492 HydrophobicContact CG1-CG 4.43Å; I235-A495 HydrophobicContact CG2-CB 4.32Å; I235-K498 PolarHBondContact O-NZ 3.33Å
236	H	67.7	Low	79.2	Confident	149 Å²	149	48 Å²	48	69%	0.69	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	46.8	59.3	-176.2	-64.6	-27.2	0	0	0	111.7	F232 E233 E234 K498	F232-H236 PolarHBondContact O-N 2.91Å; F232-H236 VanDerWaalsContact O-N 3.07Å; E233-H236 PolarHBondContact O-CE1 2.92Å; E233-H236 VanDerWaalsContact O-CE1 3.3Å; E233-H236 PolarHBondContact O-N 2.85Å; E233-H236 PolarHBondContact O-ND1 3.27Å; E234-H236 VanDerWaalsContact C-N 3.28Å; E234-H236 PolarHBondContact O-N 3.48Å; H236-K498 PolarHBondContact O-NZ 2.95Å
237	I	69.9	Low	79.9	Confident	32 Å²	32	45.2 Å²	45.2	16%	0.164	23%	0.228	C	C	.	.			trans	-74.6	165.3	178.9	-55.1	174.7	0	0	0	109.6	F232 I235 E239 L241 V491	F232-I237 HydrophobicContact CB-CD1 4.1Å; F232-I237 HydrophobicContact CD1-CD1 3.36Å; F232-I237 HydrophobicContact CD2-CD1 4.49Å; F232-I237 HydrophobicContact CE1-CD1 3.87Å; F232-I237 HydrophobicContact CG-CD1 3.73Å; F232-I237 PolarHBondContact O-N 3.32Å; I235-I237 HydrophobicContact CB-CD1 4.35Å; I235-I237 HydrophobicContact CB-CG1 4.04Å; I235-I237 HydrophobicContact CG2-CD1 4.25Å; I235-I237 HydrophobicContact CG2-CG1 3.81Å; I235-I237 PolarHBondContact O-N 2.67Å; I237-E239 PolarHBondContact O-N 3.48Å; I237-L241 HydrophobicContact CG2-CB 4.45Å; I237-L241 HydrophobicContact CG2-CD2 3.86Å; I237-V491 HydrophobicContact CD1-CG1 3.35Å; I237-V491 HydrophobicContact CG1-CG1 4.45Å
238	N	74.3	Confident	80.4	Confident	64 Å²	64	44.8 Å²	44.8	34%	0.342	22%	0.224	S	C	.	.			trans	-45.1	122.6	175.5	-178.4	-16.6	0	0	0	111.6	L240 L241 H242	N238-L240 PolarHBondContact O-N 3.38Å; N238-L240 VanDerWaalsContact O-N 3.11Å; N238-L240 VanDerWaalsContact OD1-CB 3.28Å; N238-L240 WeakPolarHBondContact OD1-CB 3.45Å; N238-L240 PolarHBondContact OD1-N 3.16Å; N238-L241 WeakPolarHBondContact O-CB 3.37Å; N238-L241 PolarHBondContact O-N 3Å; N238-H242 PolarHBondContact O-N 3.22Å
239	E	78.8	Confident	80.9	Confident	160 Å²	160	44.9 Å²	44.9	75%	0.748	23%	0.225	S	C	*	.	H	α-helix	trans	-54.3	-31.9	-179.1	-62.3	-178.2	179.3	0	0	112.5	I237 L241 H242 I243	I237-E239 PolarHBondContact O-N 3.48Å; E239-L241 VanDerWaalsContact C-N 3.32Å; E239-L241 PolarHBondContact O-N 3.08Å; E239-H242 PolarHBondContact O-N 3.46Å; E239-I243 WeakPolarHBondContact O-CG2 3.46Å; E239-I243 PolarHBondContact O-N 3.13Å
240	L	81.3	Confident	81.2	Confident	54 Å²	54	44.7 Å²	44.7	28%	0.283	22%	0.224	S	C	.	.	H	α-helix	trans	-66.3	-29.9	176.2	-64.4	174.1	0	0	0	113.3	N171 N238 L244 V428	N171-L240 WeakPolarHBondContact ND2-CD2 3.42Å; N238-L240 PolarHBondContact O-N 3.38Å; N238-L240 VanDerWaalsContact O-N 3.11Å; N238-L240 VanDerWaalsContact OD1-CB 3.28Å; N238-L240 WeakPolarHBondContact OD1-CB 3.45Å; N238-L240 PolarHBondContact OD1-N 3.16Å; L240-L244 VanDerWaalsContact O-CB 3.26Å; L240-L244 WeakPolarHBondContact O-CB 3.21Å; L240-L244 PolarHBondContact O-N 3.1Å; L240-V428 HydrophobicContact CD1-CG1 4.25Å
241	L	83.4	Confident	81.9	Confident	6 Å²	6	43.1 Å²	43.1	3%	0.031	21%	0.208	C	C	.	.	H	α-helix	trans	-78.1	-44.2	176.9	-165.7	67.1	0	0	0	110.3	F232 I237 N238 E239 L244 V245 L430 D434 I437 V438	F232-L241 HydrophobicContact CE2-CD2 4.23Å; F232-L241 HydrophobicContact CE2-CG 4.29Å; F232-L241 HydrophobicContact CZ-CD2 4.44Å; I237-L241 HydrophobicContact CG2-CB 4.45Å; I237-L241 HydrophobicContact CG2-CD2 3.86Å; N238-L241 WeakPolarHBondContact O-CB 3.37Å; N238-L241 PolarHBondContact O-N 3Å; E239-L241 VanDerWaalsContact C-N 3.32Å; E239-L241 PolarHBondContact O-N 3.08Å; L241-L244 PolarHBondContact O-N 2.74Å; L241-V245 PolarHBondContact O-N 3.13Å; L241-L430 HydrophobicContact CD1-CD2 4.48Å; L241-D434 HydrophobicContact CD1-CB 3.98Å; L241-I437 HydrophobicContact CD2-CG2 3.94Å; L241-V438 HydrophobicContact CD1-CG2 3.52Å; L241-V438 HydrophobicContact CG-CG2 4.46Å
242	H	86.3	Confident	82.6	Confident	58 Å²	58	42.3 Å²	42.3	27%	0.269	20%	0.203	S	C	.	.	H	α-helix	trans	-57.9	-50.2	176.7	179.3	-80.9	0	0	0	111.6	N238 E239 L244 F246	N238-H242 PolarHBondContact O-N 3.22Å; E239-H242 PolarHBondContact O-N 3.46Å; H242-L244 VanDerWaalsContact C-N 3.29Å; H242-L244 PolarHBondContact O-N 2.78Å; H242-F246 VanDerWaalsContact O-CB 3.25Å; H242-F246 WeakPolarHBondContact O-CB 3.28Å; H242-F246 PolarHBondContact O-N 2.99Å
243	I	87.4	Confident	83.2	Confident	3 Å²	3	43.3 Å²	43.3	2%	0.015	21%	0.209	C	C	.	.	H	α-helix	trans	-67.9	-28.1	179.7	-165.4	49.7	0	0	0	113.3	L163 P164 A167 F168 I175 E239 F246 G247	L163-I243 HydrophobicContact CD1-CD1 3.96Å; P164-I243 HydrophobicContact CG-CD1 3.67Å; P164-I243 HydrophobicContact CG-CG1 4.49Å; A167-I243 HydrophobicContact CB-CB 4.48Å; A167-I243 HydrophobicContact CB-CG1 4.16Å; A167-I243 HydrophobicContact CB-CG2 4.39Å; F168-I243 HydrophobicContact CB-CD1 4.21Å; F168-I243 HydrophobicContact CB-CG1 4.3Å; F168-I243 HydrophobicContact CD2-CD1 4.18Å; F168-I243 HydrophobicContact CD2-CG1 4.47Å; I175-I243 HydrophobicContact CD1-CG1 4.46Å; E239-I243 WeakPolarHBondContact O-CG2 3.46Å; E239-I243 PolarHBondContact O-N 3.13Å; I243-F246 HydrophobicContact CD1-CD1 4.11Å; I243-G247 PolarHBondContact O-N 3.14Å
244	L	87.9	Confident	84	Confident	3 Å²	3	36.8 Å²	36.8	2%	0.016	18%	0.178	C	C	.	.	H	α-helix	trans	-71.1	-49.4	177.8	-173.5	158.1	0	0	0	111	T174 F178 L240 L241 H242 G247 E248 L430 V438	T174-L244 HydrophobicContact CG2-CD1 3.75Å; T174-L244 HydrophobicContact CG2-CG 4.47Å; F178-L244 HydrophobicContact CD2-CD1 4.33Å; F178-L244 HydrophobicContact CD2-CD2 3.9Å; F178-L244 HydrophobicContact CD2-CG 4.18Å; F178-L244 HydrophobicContact CE2-CD1 3.89Å; F178-L244 HydrophobicContact CE2-CD2 3.95Å; F178-L244 HydrophobicContact CE2-CG 4.21Å; L240-L244 VanDerWaalsContact O-CB 3.26Å; L240-L244 WeakPolarHBondContact O-CB 3.21Å; L240-L244 PolarHBondContact O-N 3.1Å; L241-L244 PolarHBondContact O-N 2.74Å; H242-L244 VanDerWaalsContact C-N 3.29Å; H242-L244 PolarHBondContact O-N 2.78Å; L244-G247 PolarHBondContact O-N 2.98Å; L244-E248 VanDerWaalsContact O-CB 3.22Å; L244-E248 WeakPolarHBondContact O-CB 3.21Å; L244-E248 PolarHBondContact O-N 3.44Å; L244-L430 HydrophobicContact CD1-CD1 4.12Å; L244-L430 HydrophobicContact CD1-CD2 4.34Å; L244-V438 HydrophobicContact CD2-CG1 4.33Å; L244-V438 HydrophobicContact CD2-CG2 4.32Å
245	V	88	Confident	84.9	Confident	4 Å²	4	31.7 Å²	31.7	2%	0.024	15%	0.154	C	C	.	.	H	α-helix	trans	-67.1	-40.8	178.5	174.6	0	0	0	0	111.7	P225 L229 F232 L241 S249 V438	P225-V245 HydrophobicContact CB-CG1 3.87Å; L229-V245 HydrophobicContact CD2-CG1 4.4Å; F232-V245 HydrophobicContact CE2-CG2 4.18Å; L241-V245 PolarHBondContact O-N 3.13Å; V245-S249 PolarHBondContact O-N 2.96Å; V245-S249 PolarHBondContact O-OG 3.47Å; V245-S249 VanDerWaalsContact O-OG 3.07Å; V245-V438 HydrophobicContact CG2-CG2 3.83Å
246	F	88.3	Confident	85.8	Confident	36 Å²	36	30.1 Å²	30.1	16%	0.158	15%	0.147	C	C	.	.	H	α-helix	trans	-62.9	-48.9	175.4	179.4	-123.8	0	0	0	111.9	A159 L163 L229 H242 I243 S249 L250	A159-F246 HydrophobicContact CB-CE2 4.02Å; A159-F246 HydrophobicContact CB-CZ 3.82Å; L163-F246 HydrophobicContact CB-CE1 4.49Å; L163-F246 HydrophobicContact CD1-CD1 3.76Å; L163-F246 HydrophobicContact CD1-CE1 3.45Å; L163-F246 VanDerWaalsContact CD1-CE1 3.45Å; L229-F246 HydrophobicContact CD1-CB 3.96Å; L229-F246 HydrophobicContact CD1-CD2 3.54Å; L229-F246 HydrophobicContact CD1-CE2 4.46Å; L229-F246 HydrophobicContact CD1-CG 4.17Å; L229-F246 HydrophobicContact CD2-CB 4.05Å; H242-F246 VanDerWaalsContact O-CB 3.25Å; H242-F246 WeakPolarHBondContact O-CB 3.28Å; H242-F246 PolarHBondContact O-N 2.99Å; I243-F246 HydrophobicContact CD1-CD1 4.11Å; F246-S249 PolarHBondContact O-N 3.28Å; F246-L250 HydrophobicContact CE1-CD1 4.34Å; F246-L250 HydrophobicContact CE2-CD1 4.37Å; F246-L250 HydrophobicContact CZ-CD1 3.98Å; F246-L250 VanDerWaalsContact O-CB 3.29Å; F246-L250 WeakPolarHBondContact O-CB 3.26Å; F246-L250 PolarHBondContact O-N 2.78Å; F246-L250 VanDerWaalsContact O-N 3.08Å
247	G	89.6	Confident	86.9	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-69.1	-34.4	-180	0	0	0	0	0	113.6	I175 I243 L244 L251	I175-G247 WeakPolarHBondContact CG2-O 3.45Å; I243-G247 PolarHBondContact O-N 3.14Å; L244-G247 PolarHBondContact O-N 2.98Å; G247-L251 PolarHBondContact O-N 3.32Å
248	E	90.1	Very high	87.9	Confident	4 Å²	4	22.5 Å²	22.5	2%	0.019	11%	0.112	C	C	.	.	H	α-helix	trans	-56.8	-56	173.5	175	-172.1	171.8	0	0	109.8	F178 L244 L251 N252 R411	F178-E248 HydrophobicContact CB-CB 4.3Å; F178-E248 HydrophobicContact CB-CG 3.95Å; L244-E248 VanDerWaalsContact O-CB 3.22Å; L244-E248 WeakPolarHBondContact O-CB 3.21Å; L244-E248 PolarHBondContact O-N 3.44Å; E248-L251 PolarHBondContact O-N 3.07Å; E248-N252 WeakPolarHBondContact O-CB 3.37Å; E248-N252 PolarHBondContact O-N 2.91Å; E248-R411 IonicContact OE1-CZ 2.65Å; E248-R411 IonicContact OE1-NH1 3.07Å; E248-R411 PolarHBondContact OE1-NH1 3.49Å; E248-R411 IonicContact OE1-NH2 2.64Å; E248-R411 PolarHBondContact OE1-NH2 3.3Å; E248-R411 IonicContact OE2-NH2 3.4Å; E248-R411 PolarHBondContact OE2-NH2 3.25Å
249	S	88.6	Confident	88.7	Confident	2 Å²	2	19.7 Å²	19.7	1%	0.014	10%	0.097	C	C	.	.	H	α-helix	trans	-67.2	-46.6	-173.6	-56.3	0	0	0	0	112.4	V223 P225 V245 F246 L251 N252 D253	V223-S249 WeakPolarHBondContact O-CB 3.4Å; V223-S249 PolarHBondContact O-OG 3.41Å; P225-S249 WeakPolarHBondContact CB-OG 3.42Å; P225-S249 VanDerWaalsContact CD-CB 3.45Å; P225-S249 VanDerWaalsContact CG-CB 3.5Å; P225-S249 WeakPolarHBondContact CG-OG 3.45Å; V245-S249 PolarHBondContact O-N 2.96Å; V245-S249 PolarHBondContact O-OG 3.47Å; V245-S249 VanDerWaalsContact O-OG 3.07Å; F246-S249 PolarHBondContact O-N 3.28Å; S249-L251 PolarHBondContact O-N 3.05Å; S249-N252 WeakPolarHBondContact O-CB 3.34Å; S249-N252 PolarHBondContact O-N 2.9Å; S249-N252 VanDerWaalsContact O-N 3.08Å; S249-D253 PolarHBondContact O-N 3.01Å
250	L	89.4	Confident	89.3	Confident	15 Å²	15	12.1 Å²	12.1	8%	0.079	6%	0.061	C	C	.	.	H	α-helix	trans	-57.5	-36.1	179.7	178.2	151.6	0	0	0	112.8	A159 F246 I343	A159-L250 HydrophobicContact CB-CD1 3.68Å; F246-L250 HydrophobicContact CE1-CD1 4.34Å; F246-L250 HydrophobicContact CE2-CD1 4.37Å; F246-L250 HydrophobicContact CZ-CD1 3.98Å; F246-L250 VanDerWaalsContact O-CB 3.29Å; F246-L250 WeakPolarHBondContact O-CB 3.26Å; F246-L250 PolarHBondContact O-N 2.78Å; F246-L250 VanDerWaalsContact O-N 3.08Å; L250-I343 HydrophobicContact CD2-CD1 3.64Å; L250-I343 HydrophobicContact CD2-CG1 3.94Å; L250-I343 HydrophobicContact CD2-CG2 3.8Å; L250-I343 HydrophobicContact CG-CD1 4.27Å; L250-I343 WeakPolarHBondContact O-CD1 3.22Å
251	L	91.3	Very high	89.5	Confident	16 Å²	16	13.3 Å²	13.3	8%	0.084	7%	0.065	C	C	.	.	H	α-helix	trans	-87.9	-29.4	175.4	-68.6	-178.5	0	0	0	112.8	F168 I175 A179 G247 E248 S249 A254 V255 M340 I343	F168-L251 HydrophobicContact CZ-CD1 4.18Å; I175-L251 HydrophobicContact CG2-CD1 4.11Å; A179-L251 HydrophobicContact CB-CB 3.45Å; A179-L251 VanDerWaalsContact CB-CB 3.45Å; A179-L251 HydrophobicContact CB-CD1 4.3Å; G247-L251 PolarHBondContact O-N 3.32Å; E248-L251 PolarHBondContact O-N 3.07Å; S249-L251 PolarHBondContact O-N 3.05Å; L251-A254 WeakPolarHBondContact O-CB 3.35Å; L251-A254 PolarHBondContact O-N 3.46Å; L251-V255 WeakPolarHBondContact O-CG2 3.48Å; L251-V255 PolarHBondContact O-N 3.09Å; L251-M340 HydrophobicContact CD2-CE 4.4Å; L251-M340 HydrophobicContact CD2-SD 4.08Å; L251-I343 HydrophobicContact CD2-CD1 4.35Å
252	N	92.3	Very high	89.8	Confident	0 Å²	0	14 Å²	14	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-59.4	-46.6	174.9	176.1	11.1	0	0	0	111.3	T183 S221 V223 E248 S249 A254 V255 T256	T183-N252 HydrophobicContact CG2-CB 3.66Å; T183-N252 WeakPolarHBondContact CG2-OD1 3.35Å; S221-N252 PolarHBondContact O-ND2 3.47Å; V223-N252 WeakPolarHBondContact CB-ND2 3.13Å; V223-N252 PolarHBondContact N-ND2 3.26Å; V223-N252 VanDerWaalsContact N-ND2 3.11Å; E248-N252 WeakPolarHBondContact O-CB 3.37Å; E248-N252 PolarHBondContact O-N 2.91Å; S249-N252 WeakPolarHBondContact O-CB 3.34Å; S249-N252 PolarHBondContact O-N 2.9Å; S249-N252 VanDerWaalsContact O-N 3.08Å; N252-A254 PolarHBondContact O-N 2.88Å; N252-V255 CarbonylContact O-C 3.55Å; N252-V255 PolarHBondContact O-N 3.09Å; N252-T256 WeakPolarHBondContact O-CB 3.11Å; N252-T256 PolarHBondContact O-N 2.74Å; N252-T256 PolarHBondContact O-OG1 3.03Å; N252-T256 PolarHBondContact OD1-OG1 3.42Å
253	D	91	Very high	89.9	Confident	26 Å²	26	11.7 Å²	11.7	14%	0.139	6%	0.058	C	C	.	.	H	α-helix	trans	-55.4	-42.2	179.3	-70.1	-21.2	0	0	0	111.7	S249 V257 I447	S249-D253 PolarHBondContact O-N 3.01Å; D253-V257 WeakPolarHBondContact O-CG2 3.22Å; D253-V257 PolarHBondContact O-N 3.2Å; D253-I447 HydrophobicContact CB-CD1 3.67Å; D253-I447 VanDerWaalsContact CG-CD1 3.44Å
254	A	91.6	Very high	89.7	Confident	0 Å²	0	12.7 Å²	12.7	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-66.5	-43.6	175.7	0	0	0	0	0	112.7	L251 N252 V258 I339 M340 I343	L251-A254 WeakPolarHBondContact O-CB 3.35Å; L251-A254 PolarHBondContact O-N 3.46Å; N252-A254 PolarHBondContact O-N 2.88Å; A254-V258 WeakPolarHBondContact O-CG2 3.1Å; A254-V258 PolarHBondContact O-N 3.38Å; A254-I339 HydrophobicContact CB-CB 3.91Å; A254-I339 HydrophobicContact CB-CG2 3.45Å; A254-I339 VanDerWaalsContact CB-CG2 3.45Å; A254-M340 HydrophobicContact CB-CE 3.51Å; A254-M340 HydrophobicContact CB-CG 3.9Å; A254-M340 HydrophobicContact CB-SD 3.6Å; A254-I343 HydrophobicContact CB-CD1 4.29Å
255	V	93.3	Very high	89.6	Confident	1 Å²	1	18.7 Å²	18.7	1%	0.006	9%	0.091	C	C	.	.	H	α-helix	trans	-66.3	-40	177.9	168.7	0	0	0	0	111.7	V180 T183 L251 N252 V258 L259 F284 M340	V180-V255 HydrophobicContact CG2-CG2 4.07Å; T183-V255 VanDerWaalsContact OG1-CG1 3.27Å; T183-V255 WeakPolarHBondContact OG1-CG1 3.16Å; L251-V255 WeakPolarHBondContact O-CG2 3.48Å; L251-V255 PolarHBondContact O-N 3.09Å; N252-V255 CarbonylContact O-C 3.55Å; N252-V255 PolarHBondContact O-N 3.09Å; V255-V258 PolarHBondContact O-N 3.08Å; V255-L259 VanDerWaalsContact O-CB 3.31Å; V255-L259 WeakPolarHBondContact O-CB 3.24Å; V255-L259 PolarHBondContact O-N 3.09Å; V255-F284 HydrophobicContact CG1-CE2 3.99Å; V255-F284 HydrophobicContact CG1-CZ 3.83Å; V255-F284 HydrophobicContact CG2-CZ 4.32Å; V255-M340 HydrophobicContact CG2-CE 3.89Å
256	T	91.9	Very high	89.4	Confident	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-64.5	-42.5	179.1	-69.1	0	0	0	0	111.6	S218 A222 N252 L259 Y260 L451	S218-T256 WeakPolarHBondContact O-CG2 3.36Å; S218-T256 PolarHBondContact OG-O 2.84Å; A222-T256 HydrophobicContact CB-CG2 3.96Å; A222-T256 PolarHBondContact N-OG1 2.9Å; N252-T256 WeakPolarHBondContact O-CB 3.11Å; N252-T256 PolarHBondContact O-N 2.74Å; N252-T256 PolarHBondContact O-OG1 3.03Å; N252-T256 PolarHBondContact OD1-OG1 3.42Å; T256-L259 PolarHBondContact O-N 3.48Å; T256-Y260 WeakPolarHBondContact O-CB 3.38Å; T256-Y260 PolarHBondContact O-N 3.02Å; T256-L451 HydrophobicContact CG2-CD1 3.91Å
257	V	89.9	Confident	88.9	Confident	11 Å²	11	21.5 Å²	21.5	7%	0.067	11%	0.111	C	C	.	.	H	α-helix	trans	-66	-40.2	176.5	172.8	0	0	0	0	111.8	F148 D253 L259 Y260 H261 I339 I447 L451	F148-V257 HydrophobicContact CE1-CG2 4.02Å; D253-V257 WeakPolarHBondContact O-CG2 3.22Å; D253-V257 PolarHBondContact O-N 3.2Å; V257-L259 VanDerWaalsContact C-N 3.34Å; V257-L259 PolarHBondContact O-N 3.36Å; V257-Y260 PolarHBondContact O-N 3.07Å; V257-H261 PolarHBondContact O-CD2 3.07Å; V257-H261 PolarHBondContact O-N 3.33Å; V257-H261 VanDerWaalsContact O-N 3.14Å; V257-I339 HydrophobicContact CB-CD1 4.13Å; V257-I339 HydrophobicContact CG1-CD1 4.47Å; V257-I339 HydrophobicContact CG2-CD1 3.74Å; V257-I447 HydrophobicContact CG2-CG2 4.17Å; V257-L451 HydrophobicContact CG2-CD1 4.15Å; V257-L451 HydrophobicContact CG2-CD2 4.37Å
258	V	91.8	Very high	88.2	Confident	10 Å²	10	26.9 Å²	26.9	6%	0.061	14%	0.136	C	C	.	.	H	α-helix	trans	-63.9	-41	174.1	176	0	0	0	0	111.2	A254 V255 H261 L262 F284 V287	A254-V258 WeakPolarHBondContact O-CG2 3.1Å; A254-V258 PolarHBondContact O-N 3.38Å; V255-V258 PolarHBondContact O-N 3.08Å; V258-H261 PolarHBondContact O-N 3.11Å; V258-L262 WeakPolarHBondContact O-CB 3.48Å; V258-L262 PolarHBondContact O-N 3.07Å; V258-F284 HydrophobicContact CB-CD2 4.42Å; V258-F284 HydrophobicContact CB-CE2 4.3Å; V258-F284 HydrophobicContact CG1-CD2 3.6Å; V258-F284 HydrophobicContact CG1-CE2 3.94Å; V258-F284 HydrophobicContact CG1-CG 4.42Å; V258-V287 HydrophobicContact CG1-CB 4.27Å; V258-V287 HydrophobicContact CG1-CG1 3.88Å; V258-V287 HydrophobicContact CG2-CG1 3.96Å
259	L	91.6	Very high	87.5	Confident	4 Å²	4	29.1 Å²	29.1	2%	0.021	16%	0.155	C	C	.	.	H	α-helix	trans	-70.6	-32.6	178.6	-172	65.1	0	0	0	112.6	L184 A187 S218 V255 T256 V257 L262 F263	L184-L259 HydrophobicContact CD2-CD1 4.04Å; L184-L259 HydrophobicContact CD2-CD2 4.1Å; A187-L259 HydrophobicContact CB-CD2 3.56Å; S218-L259 WeakPolarHBondContact OG-CB 3.31Å; S218-L259 WeakPolarHBondContact OG-CG 3.31Å; V255-L259 VanDerWaalsContact O-CB 3.31Å; V255-L259 WeakPolarHBondContact O-CB 3.24Å; V255-L259 PolarHBondContact O-N 3.09Å; T256-L259 PolarHBondContact O-N 3.48Å; V257-L259 VanDerWaalsContact C-N 3.34Å; V257-L259 PolarHBondContact O-N 3.36Å; L259-L262 HydrophobicContact CD1-CD2 4.38Å; L259-F263 HydrophobicContact CD1-CD2 4.18Å; L259-F263 HydrophobicContact CD1-CE1 4.25Å; L259-F263 HydrophobicContact CD1-CE2 3.59Å; L259-F263 HydrophobicContact CD1-CZ 3.62Å; L259-F263 HydrophobicContact CD2-CE2 3.98Å; L259-F263 HydrophobicContact CG-CD2 3.96Å; L259-F263 HydrophobicContact CG-CE2 3.54Å; L259-F263 HydrophobicContact CG-CZ 4.13Å; L259-F263 WeakPolarHBondContact O-CD2 3.37Å; L259-F263 WeakPolarHBondContact O-CG 3.42Å; L259-F263 PolarHBondContact O-N 2.85Å; L259-F263 VanDerWaalsContact O-N 3.13Å
260	Y	89.5	Confident	86.4	Confident	1 Å²	1	37 Å²	37	0%	0.004	20%	0.197	C	C	.	.	H	α-helix	trans	-59.6	-55.7	170.7	171	-89.4	0	0	0	110.8	L215 S218 I219 T256 V257 L262 F263 E264 L451 L454 I455	L215-Y260 HydrophobicContact CD1-CE2 4.39Å; L215-Y260 HydrophobicContact CD2-CD2 4.28Å; L215-Y260 HydrophobicContact CD2-CE2 3.99Å; L215-Y260 HydrophobicContact CG-CD2 4.25Å; L215-Y260 HydrophobicContact CG-CE2 4.25Å; S218-Y260 PolarHBondContact OG-N 3.31Å; I219-Y260 HydrophobicContact CD1-CD2 3.87Å; I219-Y260 HydrophobicContact CD1-CE2 3.88Å; I219-Y260 HydrophobicContact CG1-CD2 3.69Å; I219-Y260 HydrophobicContact CG1-CE2 4.23Å; T256-Y260 WeakPolarHBondContact O-CB 3.38Å; T256-Y260 PolarHBondContact O-N 3.02Å; V257-Y260 PolarHBondContact O-N 3.07Å; Y260-L262 VanDerWaalsContact C-N 3.29Å; Y260-L262 PolarHBondContact O-N 2.91Å; Y260-F263 PolarHBondContact O-N 3.03Å; Y260-F263 VanDerWaalsContact O-N 3.17Å; Y260-E264 HydrophobicContact CE1-CB 4.32Å; Y260-E264 VanDerWaalsContact CE1-CD 3.44Å; Y260-E264 HydrophobicContact CE1-CG 4.48Å; Y260-E264 WeakPolarHBondContact CE1-OE1 3.46Å; Y260-E264 WeakPolarHBondContact CE1-OE2 3.36Å; Y260-E264 WeakPolarHBondContact O-CB 3.07Å; Y260-E264 PolarHBondContact O-N 3.39Å; Y260-E264 PolarHBondContact OH-OE1 3.49Å; Y260-L451 HydrophobicContact CD1-CD2 3.84Å; Y260-L451 HydrophobicContact CD2-CB 4.31Å; Y260-L451 HydrophobicContact CD2-CD2 4.1Å; Y260-L451 HydrophobicContact CE1-CD2 4.35Å; Y260-L451 HydrophobicContact CG-CD2 3.75Å; Y260-L454 HydrophobicContact CD1-CD2 4.32Å; Y260-L454 HydrophobicContact CE1-CB 4.42Å; Y260-L454 HydrophobicContact CE1-CD2 3.54Å; Y260-L454 HydrophobicContact CE1-CG 3.96Å; Y260-L454 WeakPolarHBondContact OH-CG 3.42Å; Y260-I455 HydrophobicContact CE2-CG1 4.4Å; Y260-I455 PolarHBondContact OH-N 3.36Å
261	H	87.2	Confident	85.6	Confident	79 Å²	79	41.7 Å²	41.7	37%	0.366	23%	0.226	S	C	.	.	H	α-helix	trans	-63.6	-35.1	-178.6	-71.5	-53.1	0	0	0	112.6	V257 V258 E264 E265	V257-H261 PolarHBondContact O-CD2 3.07Å; V257-H261 PolarHBondContact O-N 3.33Å; V257-H261 VanDerWaalsContact O-N 3.14Å; V258-H261 PolarHBondContact O-N 3.11Å; H261-E264 IonicContact CE1-OE2 3.8Å; H261-E264 IonicContact ND1-OE2 3.15Å; H261-E264 PolarHBondContact ND1-OE2 3.27Å; H261-E264 PolarHBondContact O-N 2.86Å; H261-E265 WeakPolarHBondContact O-CB 3.44Å; H261-E265 PolarHBondContact O-N 3.21Å
262	L	89.3	Confident	84.8	Confident	20 Å²	20	44.8 Å²	44.8	11%	0.105	25%	0.246	C	C	.	.	H	α-helix	trans	-61.5	-44.6	174	-179.3	65.1	0	0	0	112.4	V258 L259 Y260 F266 F284	V258-L262 WeakPolarHBondContact O-CB 3.48Å; V258-L262 PolarHBondContact O-N 3.07Å; L259-L262 HydrophobicContact CD1-CD2 4.38Å; Y260-L262 VanDerWaalsContact C-N 3.29Å; Y260-L262 PolarHBondContact O-N 2.91Å; L262-F266 HydrophobicContact CD1-CD2 4.45Å; L262-F266 HydrophobicContact CD1-CE1 4.24Å; L262-F266 HydrophobicContact CD1-CE2 3.9Å; L262-F266 HydrophobicContact CD1-CZ 3.8Å; L262-F266 HydrophobicContact CD2-CE2 4.47Å; L262-F266 HydrophobicContact CG-CD2 4.32Å; L262-F266 HydrophobicContact CG-CE2 3.96Å; L262-F266 HydrophobicContact CG-CZ 4.39Å; L262-F266 WeakPolarHBondContact O-CB 3.39Å; L262-F266 WeakPolarHBondContact O-CD2 3.48Å; L262-F266 VanDerWaalsContact O-CG 3.28Å; L262-F266 WeakPolarHBondContact O-CG 3.49Å; L262-F266 PolarHBondContact O-N 3.1Å; L262-F266 VanDerWaalsContact O-N 3.12Å; L262-F284 HydrophobicContact CD2-CB 4.45Å
263	F	87.4	Confident	84.3	Confident	10 Å²	10	48.8 Å²	48.8	4%	0.044	27%	0.27	C	S	.	.	H	α-helix	trans	-76	-26.7	177.8	-67.2	-36.1	0	0	0	113.3	F188 L211 L214 L215 L259 Y260 F266 S267	F188-F263 HydrophobicContact CE1-CE1 4.49Å; F188-F263 AromaticContact CE1-CZ 3.93Å; F188-F263 HydrophobicContact CE1-CZ 3.93Å; F188-F263 HydrophobicContact CZ-CZ 4.13Å; L211-F263 HydrophobicContact CD1-CB 4.3Å; L211-F263 HydrophobicContact CD1-CD1 3.91Å; L211-F263 HydrophobicContact CD1-CG 4.38Å; L214-F263 HydrophobicContact CB-CD2 4.23Å; L214-F263 HydrophobicContact CB-CE1 4.42Å; L214-F263 HydrophobicContact CB-CE2 3.98Å; L214-F263 HydrophobicContact CB-CZ 4.09Å; L214-F263 WeakPolarHBondContact O-CD2 3.15Å; L214-F263 WeakPolarHBondContact O-CE2 3.42Å; L215-F263 HydrophobicContact CB-CB 4.02Å; L215-F263 HydrophobicContact CD1-CB 4.42Å; L215-F263 HydrophobicContact CG-CB 4.42Å; L259-F263 HydrophobicContact CD1-CD2 4.18Å; L259-F263 HydrophobicContact CD1-CE1 4.25Å; L259-F263 HydrophobicContact CD1-CE2 3.59Å; L259-F263 HydrophobicContact CD1-CZ 3.62Å; L259-F263 HydrophobicContact CD2-CE2 3.98Å; L259-F263 HydrophobicContact CG-CD2 3.96Å; L259-F263 HydrophobicContact CG-CE2 3.54Å; L259-F263 HydrophobicContact CG-CZ 4.13Å; L259-F263 WeakPolarHBondContact O-CD2 3.37Å; L259-F263 WeakPolarHBondContact O-CG 3.42Å; L259-F263 PolarHBondContact O-N 2.85Å; L259-F263 VanDerWaalsContact O-N 3.13Å; Y260-F263 PolarHBondContact O-N 3.03Å; Y260-F263 VanDerWaalsContact O-N 3.17Å; F263-F266 HydrophobicContact CD1-CD2 4.3Å; F263-S267 WeakPolarHBondContact O-CB 3.39Å; F263-S267 PolarHBondContact O-N 3.24Å; F263-S267 VanDerWaalsContact O-N 3.14Å
264	E	84.7	Confident	83.8	Confident	24 Å²	24	53.8 Å²	53.8	11%	0.112	30%	0.301	C	S	.	.	H	α-helix	trans	-67	-49.1	171.3	179.9	173.1	-119.7	0	0	110.9	L215 Y260 H261 F266 S267 H268 H456	L215-E264 HydrophobicContact CD1-CB 4.24Å; Y260-E264 HydrophobicContact CE1-CB 4.32Å; Y260-E264 VanDerWaalsContact CE1-CD 3.44Å; Y260-E264 HydrophobicContact CE1-CG 4.48Å; Y260-E264 WeakPolarHBondContact CE1-OE1 3.46Å; Y260-E264 WeakPolarHBondContact CE1-OE2 3.36Å; Y260-E264 WeakPolarHBondContact O-CB 3.07Å; Y260-E264 PolarHBondContact O-N 3.39Å; Y260-E264 PolarHBondContact OH-OE1 3.49Å; H261-E264 IonicContact CE1-OE2 3.8Å; H261-E264 IonicContact ND1-OE2 3.15Å; H261-E264 PolarHBondContact ND1-OE2 3.27Å; H261-E264 PolarHBondContact O-N 2.86Å; E264-F266 VanDerWaalsContact C-N 3.35Å; E264-F266 PolarHBondContact O-N 3.42Å; E264-S267 WeakPolarHBondContact O-CA 3.1Å; E264-S267 VanDerWaalsContact O-CB 3.31Å; E264-S267 WeakPolarHBondContact O-CB 3.49Å; E264-S267 PolarHBondContact O-N 3.39Å; E264-H268 PolarHBondContact O-CD2 3.39Å; E264-H268 PolarHBondContact O-N 3.47Å; E264-H456 IonicContact OE1-CE1 2.95Å; E264-H456 PolarHBondContact OE1-CE1 3.5Å; E264-H456 VanDerWaalsContact OE1-CE1 3.25Å; E264-H456 IonicContact OE1-ND1 2.61Å; E264-H456 PolarHBondContact OE1-ND1 3.21Å
265	E	84.2	Confident	83.4	Confident	130 Å²	130	55.9 Å²	55.9	61%	0.607	32%	0.323	S	S	*	.	H	α-helix	trans	-59.7	-43.6	175.8	-173.2	173.2	-156.3	0	0	111.6	H261 S267 H268	H261-E265 WeakPolarHBondContact O-CB 3.44Å; H261-E265 PolarHBondContact O-N 3.21Å; E265-S267 PolarHBondContact O-N 3.26Å; E265-H268 PolarHBondContact O-N 3.41Å
266	F	84	Confident	83	Confident	35 Å²	35	58.6 Å²	58.6	15%	0.154	34%	0.338	C	S	.	.	H	α-helix	trans	-63.6	-21.1	171.7	-71.1	-19.1	0	0	0	114.2	L211 L262 F263 E264 H268 A269 D276	L211-F266 HydrophobicContact CD1-CB 4.11Å; L211-F266 HydrophobicContact CD2-CB 3.84Å; L211-F266 WeakPolarHBondContact CD2-O 3.25Å; L262-F266 HydrophobicContact CD1-CD2 4.45Å; L262-F266 HydrophobicContact CD1-CE1 4.24Å; L262-F266 HydrophobicContact CD1-CE2 3.9Å; L262-F266 HydrophobicContact CD1-CZ 3.8Å; L262-F266 HydrophobicContact CD2-CE2 4.47Å; L262-F266 HydrophobicContact CG-CD2 4.32Å; L262-F266 HydrophobicContact CG-CE2 3.96Å; L262-F266 HydrophobicContact CG-CZ 4.39Å; L262-F266 WeakPolarHBondContact O-CB 3.39Å; L262-F266 WeakPolarHBondContact O-CD2 3.48Å; L262-F266 VanDerWaalsContact O-CG 3.28Å; L262-F266 WeakPolarHBondContact O-CG 3.49Å; L262-F266 PolarHBondContact O-N 3.1Å; L262-F266 VanDerWaalsContact O-N 3.12Å; F263-F266 HydrophobicContact CD1-CD2 4.3Å; E264-F266 VanDerWaalsContact C-N 3.35Å; E264-F266 PolarHBondContact O-N 3.42Å; F266-H268 VanDerWaalsContact C-N 3.27Å; F266-A269 PolarHBondContact O-N 3.08Å; F266-D276 WeakPolarHBondContact CZ-O 3.32Å
267	S	78.8	Confident	82.6	Confident	64 Å²	64	60.9 Å²	60.9	45%	0.448	36%	0.356	S	S	.	.	H	α-helix	trans	-80.8	-11.8	178.6	-165.2	0	0	0	0	112.9	L211 F263 E264 E265	L211-S267 VanDerWaalsContact CD2-N 3.34Å; F263-S267 WeakPolarHBondContact O-CB 3.39Å; F263-S267 PolarHBondContact O-N 3.24Å; F263-S267 VanDerWaalsContact O-N 3.14Å; E264-S267 WeakPolarHBondContact O-CA 3.1Å; E264-S267 VanDerWaalsContact O-CB 3.31Å; E264-S267 WeakPolarHBondContact O-CB 3.49Å; E264-S267 PolarHBondContact O-N 3.39Å; E265-S267 PolarHBondContact O-N 3.26Å
268	H	75.1	Confident	82.5	Confident	113 Å²	113	67.6 Å²	67.6	52%	0.523	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.9	-4.9	169.7	-63.5	-67.5	0	0	0	112.8	E264 E265 F266 H456	E264-H268 PolarHBondContact O-CD2 3.39Å; E264-H268 PolarHBondContact O-N 3.47Å; E265-H268 PolarHBondContact O-N 3.41Å; F266-H268 VanDerWaalsContact C-N 3.27Å; H268-H456 AromaticContact NE2-CE1 3.91Å; H268-H456 AromaticContact NE2-NE2 4Å
269	A	75.8	Confident	82.3	Confident	50 Å²	50	72.3 Å²	72.3	41%	0.413	41%	0.409	S	S	.	.			trans	-93.6	118.1	176.1	0	0	0	0	0	111.1	F266 T271	F266-A269 PolarHBondContact O-N 3.08Å; A269-T271 PolarHBondContact O-N 3.43Å
270	D	65.4	Low	82	Confident	169 Å²	169	72.2 Å²	72.2	90%	0.904	41%	0.41	S	S	*	.	S	Bend	trans	-60.1	-29.8	-175.2	-68.1	-48.1	0	0	0	114.2
271	T	72.9	Confident	82	Confident	112 Å²	112	76 Å²	76	69%	0.687	43%	0.432	S	S	*	.			trans	-140	132.4	174	55	0	0	0	0	111.1	A269	A269-T271 PolarHBondContact O-N 3.43Å
272	V	73.5	Confident	82.2	Confident	82 Å²	82	75 Å²	75	50%	0.497	43%	0.432	S	S	.	.			trans	-101.6	111.5	177.7	-177.5	0	0	0	0	109.5	D276	V272-D276 HydrophobicContact CG1-CB 4.42Å
273	T	81.9	Confident	82.2	Confident	84 Å²	84	76 Å²	76	52%	0.515	44%	0.44	S	S	.	.			trans	-88.3	159.4	176.6	-43.3	0	0	0	0	110.5	G275 D276 A277	T273-G275 PolarHBondContact O-N 3.14Å; T273-D276 WeakPolarHBondContact CA-OD2 3.3Å; T273-D276 WeakPolarHBondContact CB-OD2 3.19Å; T273-D276 PolarHBondContact N-OD2 3.41Å; T273-D276 WeakPolarHBondContact O-CB 3.27Å; T273-D276 PolarHBondContact O-N 3.37Å; T273-D276 PolarHBondContact OG1-OD2 2.94Å; T273-A277 PolarHBondContact O-N 2.96Å; T273-A277 VanDerWaalsContact O-N 3.13Å
274	V	80.8	Confident	82.4	Confident	130 Å²	130	76.2 Å²	76.2	79%	0.788	44%	0.441	S	S	*	.	H	α-helix	trans	-57.3	-30.3	172.5	-177	0	0	0	0	112.1	F278	V274-F278 PolarHBondContact O-N 2.94Å
275	G	82.2	Confident	82.7	Confident	45 Å²	45	80.3 Å²	80.3	46%	0.464	46%	0.459	S	S	.	.	H	α-helix	trans	-64.3	-40.6	172.5	0	0	0	0	0	113	T273 F278 L279	T273-G275 PolarHBondContact O-N 3.14Å; G275-F278 PolarHBondContact O-N 3.44Å; G275-L279 PolarHBondContact O-N 3.22Å
276	D	84.4	Confident	83.2	Confident	58 Å²	58	78.2 Å²	78.2	31%	0.31	46%	0.455	S	S	.	.	H	α-helix	trans	-70.4	-36.6	-179.6	-48.7	-43.7	0	0	0	110.7	F266 V272 T273 F278 L279 G280	F266-D276 WeakPolarHBondContact CZ-O 3.32Å; V272-D276 HydrophobicContact CG1-CB 4.42Å; T273-D276 WeakPolarHBondContact CA-OD2 3.3Å; T273-D276 WeakPolarHBondContact CB-OD2 3.19Å; T273-D276 PolarHBondContact N-OD2 3.41Å; T273-D276 WeakPolarHBondContact O-CB 3.27Å; T273-D276 PolarHBondContact O-N 3.37Å; T273-D276 PolarHBondContact OG1-OD2 2.94Å; D276-F278 VanDerWaalsContact C-N 3.35Å; D276-F278 PolarHBondContact O-N 3.2Å; D276-L279 CarbonylContact O-C 3.59Å; D276-L279 PolarHBondContact O-N 2.62Å; D276-G280 PolarHBondContact O-N 3.4Å
277	A	84.1	Confident	83.6	Confident	48 Å²	48	77.9 Å²	77.9	40%	0.397	46%	0.456	S	S	.	.	H	α-helix	trans	-61.2	-40.7	171.4	0	0	0	0	0	112.4	T273 G280 V281	T273-A277 PolarHBondContact O-N 2.96Å; T273-A277 VanDerWaalsContact O-N 3.13Å; A277-G280 PolarHBondContact O-N 3.29Å; A277-V281 PolarHBondContact O-N 3.44Å
278	F	88	Confident	84.3	Confident	151 Å²	151	75.4 Å²	75.4	66%	0.662	44%	0.438	S	S	*	.	H	α-helix	trans	-66.8	-42.9	173.1	178.4	-98.1	0	0	0	111.8	V274 G275 D276 G280 V281 V282	V274-F278 PolarHBondContact O-N 2.94Å; G275-F278 PolarHBondContact O-N 3.44Å; D276-F278 VanDerWaalsContact C-N 3.35Å; D276-F278 PolarHBondContact O-N 3.2Å; F278-G280 VanDerWaalsContact C-N 3.26Å; F278-G280 PolarHBondContact O-N 3.2Å; F278-V281 PolarHBondContact O-N 3.05Å; F278-V282 HydrophobicContact CD1-CG2 4.29Å; F278-V282 HydrophobicContact CE1-CG2 3.84Å; F278-V282 HydrophobicContact CZ-CG2 4.03Å; F278-V282 PolarHBondContact O-N 2.93Å
279	L	86.6	Confident	85.2	Confident	109 Å²	109	75.2 Å²	75.2	57%	0.571	44%	0.44	S	S	*	.	H	α-helix	trans	-60.5	-36.6	175.4	-175.3	60.5	0	0	0	111.7	G275 D276 V282 S283	G275-L279 PolarHBondContact O-N 3.22Å; D276-L279 CarbonylContact O-C 3.59Å; D276-L279 PolarHBondContact O-N 2.62Å; L279-V282 PolarHBondContact O-N 3Å; L279-S283 WeakPolarHBondContact O-CB 3.3Å; L279-S283 PolarHBondContact O-N 2.87Å
280	G	87.1	Confident	86.1	Confident	3 Å²	3	73.5 Å²	73.5	3%	0.031	43%	0.428	C	S	.	.	H	α-helix	trans	-64	-39.7	173.9	0	0	0	0	0	113.8	D276 A277 F278 V282 S283 F284	D276-G280 PolarHBondContact O-N 3.4Å; A277-G280 PolarHBondContact O-N 3.29Å; F278-G280 VanDerWaalsContact C-N 3.26Å; F278-G280 PolarHBondContact O-N 3.2Å; G280-V282 VanDerWaalsContact C-N 3.34Å; G280-S283 PolarHBondContact O-N 2.94Å; G280-F284 WeakPolarHBondContact O-CB 3.28Å; G280-F284 PolarHBondContact O-N 3.44Å
281	V	88.5	Confident	87.5	Confident	80 Å²	80	65.4 Å²	65.4	49%	0.485	38%	0.384	S	S	.	.	H	α-helix	trans	-63.8	-41.7	172.8	175	0	0	0	0	110.6	A277 F278 F285	A277-V281 PolarHBondContact O-N 3.44Å; F278-V281 PolarHBondContact O-N 3.05Å; V281-F285 HydrophobicContact CG1-CD2 4.14Å; V281-F285 HydrophobicContact CG1-CE2 3.87Å; V281-F285 WeakPolarHBondContact O-CD2 3.22Å; V281-F285 PolarHBondContact O-N 3.03Å
282	V	90.6	Very high	88.6	Confident	59 Å²	59	63.3 Å²	63.3	36%	0.358	37%	0.368	S	S	.	.	H	α-helix	trans	-64	-46.7	174.8	175.9	0	0	0	0	110.8	F278 L279 G280 F284 F285 V286	F278-V282 HydrophobicContact CD1-CG2 4.29Å; F278-V282 HydrophobicContact CE1-CG2 3.84Å; F278-V282 HydrophobicContact CZ-CG2 4.03Å; F278-V282 PolarHBondContact O-N 2.93Å; L279-V282 PolarHBondContact O-N 3Å; G280-V282 VanDerWaalsContact C-N 3.34Å; V282-F284 PolarHBondContact O-N 2.95Å; V282-F285 PolarHBondContact O-N 3.13Å; V282-V286 HydrophobicContact CG1-CG2 4.22Å; V282-V286 WeakPolarHBondContact O-CG2 3.43Å; V282-V286 PolarHBondContact O-N 2.95Å
283	S	89.7	Confident	89.7	Confident	39 Å²	39	64.6 Å²	64.6	27%	0.273	37%	0.372	S	S	.	.	H	α-helix	trans	-57.4	-47.4	177.4	-174.3	0	0	0	0	111.4	L279 G280 F285 V286 V287	L279-S283 WeakPolarHBondContact O-CB 3.3Å; L279-S283 PolarHBondContact O-N 2.87Å; G280-S283 PolarHBondContact O-N 2.94Å; S283-F285 VanDerWaalsContact C-N 3.3Å; S283-F285 PolarHBondContact O-N 2.84Å; S283-V286 PolarHBondContact O-N 3.09Å; S283-V287 WeakPolarHBondContact O-CB 3.48Å; S283-V287 WeakPolarHBondContact O-CG2 3.13Å; S283-V287 PolarHBondContact O-N 3.26Å
284	F	91.3	Very high	90.4	Very high	15 Å²	15	61.4 Å²	61.4	7%	0.066	35%	0.352	C	S	.	.	H	α-helix	trans	-52.4	-45.5	175.2	177.2	-90.1	0	0	0	112.6	V180 V255 V258 L262 G280 V282 S288	V180-F284 HydrophobicContact CG1-CE1 4.22Å; V180-F284 HydrophobicContact CG1-CZ 4.35Å; V255-F284 HydrophobicContact CG1-CE2 3.99Å; V255-F284 HydrophobicContact CG1-CZ 3.83Å; V255-F284 HydrophobicContact CG2-CZ 4.32Å; V258-F284 HydrophobicContact CB-CD2 4.42Å; V258-F284 HydrophobicContact CB-CE2 4.3Å; V258-F284 HydrophobicContact CG1-CD2 3.6Å; V258-F284 HydrophobicContact CG1-CE2 3.94Å; V258-F284 HydrophobicContact CG1-CG 4.42Å; L262-F284 HydrophobicContact CD2-CB 4.45Å; G280-F284 WeakPolarHBondContact O-CB 3.28Å; G280-F284 PolarHBondContact O-N 3.44Å; V282-F284 PolarHBondContact O-N 2.95Å; F284-S288 WeakPolarHBondContact O-CB 3.27Å; F284-S288 PolarHBondContact O-N 3.47Å; F284-S288 VanDerWaalsContact O-N 3.11Å; F284-S288 PolarHBondContact O-OG 3.31Å
285	F	92.2	Very high	91.1	Very high	110 Å²	110	55.2 Å²	55.2	48%	0.482	31%	0.314	S	S	.	.	H	α-helix	trans	-70.4	-39.2	176	-75.5	-64.9	0	0	0	112.7	V281 V282 S283 L289	V281-F285 HydrophobicContact CG1-CD2 4.14Å; V281-F285 HydrophobicContact CG1-CE2 3.87Å; V281-F285 WeakPolarHBondContact O-CD2 3.22Å; V281-F285 PolarHBondContact O-N 3.03Å; V282-F285 PolarHBondContact O-N 3.13Å; S283-F285 VanDerWaalsContact C-N 3.3Å; S283-F285 PolarHBondContact O-N 2.84Å; F285-L289 WeakPolarHBondContact O-CB 3.35Å; F285-L289 WeakPolarHBondContact O-CG 3.13Å; F285-L289 PolarHBondContact O-N 2.87Å
286	V	93.9	Very high	91.7	Very high	87 Å²	87	55.7 Å²	55.7	53%	0.527	31%	0.308	S	S	.	.	H	α-helix	trans	-65.3	-47.8	178	170.9	0	0	0	0	111.5	V282 S283 S288 G290	V282-V286 HydrophobicContact CG1-CG2 4.22Å; V282-V286 WeakPolarHBondContact O-CG2 3.43Å; V282-V286 PolarHBondContact O-N 2.95Å; S283-V286 PolarHBondContact O-N 3.09Å; V286-S288 PolarHBondContact O-N 2.91Å; V286-G290 WeakPolarHBondContact O-CA 3.04Å; V286-G290 PolarHBondContact O-N 3.33Å
287	V	93.3	Very high	92.3	Very high	28 Å²	28	57 Å²	57	17%	0.17	31%	0.314	C	S	.	.	H	α-helix	trans	-62.4	-41.8	177.8	171.4	0	0	0	0	111.2	V258 S283 G291 S337	V258-V287 HydrophobicContact CG1-CB 4.27Å; V258-V287 HydrophobicContact CG1-CG1 3.88Å; V258-V287 HydrophobicContact CG2-CG1 3.96Å; S283-V287 WeakPolarHBondContact O-CB 3.48Å; S283-V287 WeakPolarHBondContact O-CG2 3.13Å; S283-V287 PolarHBondContact O-N 3.26Å; V287-G291 PolarHBondContact O-N 3.48Å; V287-G291 VanDerWaalsContact O-N 3.09Å; V287-S337 PolarHBondContact O-N 3.18Å; V287-S337 VanDerWaalsContact O-N 3.14Å
288	S	92.3	Very high	92.8	Very high	11 Å²	11	57.6 Å²	57.6	8%	0.077	31%	0.307	C	S	.	.	H	α-helix	trans	-70.5	-50.5	178.6	-60.6	0	0	0	0	112.7	F284 V286 G291 I292	F284-S288 WeakPolarHBondContact O-CB 3.27Å; F284-S288 PolarHBondContact O-N 3.47Å; F284-S288 VanDerWaalsContact O-N 3.11Å; F284-S288 PolarHBondContact O-OG 3.31Å; V286-S288 PolarHBondContact O-N 2.91Å; S288-G291 PolarHBondContact O-N 3.05Å; S288-I292 WeakPolarHBondContact O-CG1 3.24Å; S288-I292 PolarHBondContact O-N 3.21Å; S288-I292 VanDerWaalsContact O-N 3.1Å
289	L	94.1	Very high	93.1	Very high	109 Å²	109	50.4 Å²	50.4	57%	0.571	28%	0.275	S	S	*	.	H	α-helix	trans	-71.5	-34.4	-179	-66.8	173	0	0	0	112	F285 I292 L293	F285-L289 WeakPolarHBondContact O-CB 3.35Å; F285-L289 WeakPolarHBondContact O-CG 3.13Å; F285-L289 PolarHBondContact O-N 2.87Å; L289-I292 HydrophobicContact CD2-CD1 4.49Å; L289-I292 PolarHBondContact O-N 3.26Å; L289-L293 WeakPolarHBondContact O-CB 3.14Å; L289-L293 PolarHBondContact O-N 2.89Å
290	G	94.9	Very high	93.3	Very high	14 Å²	14	47.1 Å²	47.1	14%	0.144	26%	0.26	C	S	.	.	H	α-helix	trans	-63.5	-44.5	172.8	0	0	0	0	0	111.6	V286 I292 L293 V294	V286-G290 WeakPolarHBondContact O-CA 3.04Å; V286-G290 PolarHBondContact O-N 3.33Å; G290-I292 PolarHBondContact O-N 3.42Å; G290-L293 PolarHBondContact O-N 3.47Å; G290-L293 VanDerWaalsContact O-N 3.16Å; G290-V294 WeakPolarHBondContact O-CG2 3.1Å; G290-V294 PolarHBondContact O-N 3.39Å
291	G	95.6	Very high	93.6	Very high	0 Å²	0	50.7 Å²	50.7	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-55.4	-50.4	171.4	0	0	0	0	0	111.7	V287 S288 L293 V294 G295 S341	V287-G291 PolarHBondContact O-N 3.48Å; V287-G291 VanDerWaalsContact O-N 3.09Å; S288-G291 PolarHBondContact O-N 3.05Å; G291-L293 VanDerWaalsContact C-N 3.32Å; G291-L293 PolarHBondContact O-N 3.14Å; G291-V294 PolarHBondContact O-N 3.38Å; G291-G295 PolarHBondContact O-N 2.91Å; G291-S341 WeakPolarHBondContact O-CA 3.1Å; G291-S341 VanDerWaalsContact O-CB 3.26Å; G291-S341 WeakPolarHBondContact O-CB 3.21Å
292	I	95.2	Very high	93.7	Very high	68 Å²	68	46.9 Å²	46.9	35%	0.349	26%	0.255	S	S	.	.	H	α-helix	trans	-57.2	-43.2	175.5	-66.1	169.4	0	0	0	111.6	S288 L289 G290 G295 V296 M340 A344	S288-I292 WeakPolarHBondContact O-CG1 3.24Å; S288-I292 PolarHBondContact O-N 3.21Å; S288-I292 VanDerWaalsContact O-N 3.1Å; L289-I292 HydrophobicContact CD2-CD1 4.49Å; L289-I292 PolarHBondContact O-N 3.26Å; G290-I292 PolarHBondContact O-N 3.42Å; I292-G295 PolarHBondContact O-N 3.02Å; I292-V296 HydrophobicContact CG2-CG2 4.26Å; I292-V296 VanDerWaalsContact O-CG2 3.24Å; I292-V296 WeakPolarHBondContact O-CG2 3.11Å; I292-V296 PolarHBondContact O-N 3.42Å; I292-M340 HydrophobicContact CG1-CB 4.07Å; I292-A344 HydrophobicContact CB-CB 4.43Å; I292-A344 HydrophobicContact CG2-CB 4.15Å
293	L	96.4	Very high	93.6	Very high	108 Å²	108	44.1 Å²	44.1	57%	0.565	24%	0.238	S	C	*	.	H	α-helix	trans	-63	-46.7	-179.8	179.6	62.3	0	0	0	112	L289 G290 G291 G295 V296 I297	L289-L293 WeakPolarHBondContact O-CB 3.14Å; L289-L293 PolarHBondContact O-N 2.89Å; G290-L293 PolarHBondContact O-N 3.47Å; G290-L293 VanDerWaalsContact O-N 3.16Å; G291-L293 VanDerWaalsContact C-N 3.32Å; G291-L293 PolarHBondContact O-N 3.14Å; L293-G295 VanDerWaalsContact C-N 3.33Å; L293-G295 PolarHBondContact O-N 2.96Å; L293-V296 PolarHBondContact O-N 3.26Å; L293-I297 HydrophobicContact CD1-CD1 4.38Å; L293-I297 HydrophobicContact CG-CD1 4.18Å; L293-I297 WeakPolarHBondContact O-CG1 3.18Å; L293-I297 PolarHBondContact O-N 2.85Å
294	V	96.7	Very high	93.4	Very high	17 Å²	17	45.3 Å²	45.3	10%	0.103	24%	0.238	C	C	.	.	H	α-helix	trans	-58.8	-47.2	174.3	174.6	0	0	0	0	110	G290 G291 V296 I297 Y298 A331 L336	G290-V294 WeakPolarHBondContact O-CG2 3.1Å; G290-V294 PolarHBondContact O-N 3.39Å; G291-V294 PolarHBondContact O-N 3.38Å; V294-V296 PolarHBondContact O-N 3.42Å; V294-I297 WeakPolarHBondContact O-CB 3.23Å; V294-I297 PolarHBondContact O-N 2.89Å; V294-I297 VanDerWaalsContact O-N 3.14Å; V294-Y298 HydrophobicContact CG1-CD2 3.77Å; V294-Y298 HydrophobicContact CG1-CE2 3.89Å; V294-Y298 WeakPolarHBondContact O-CD2 3.29Å; V294-Y298 PolarHBondContact O-N 3.19Å; V294-A331 HydrophobicContact CG1-CB 4.39Å; V294-L336 HydrophobicContact CG2-CD1 3.9Å
295	G	96.3	Very high	93.3	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-58.5	-42.2	177	0	0	0	0	0	113.7	G291 I292 L293 G299 S341 C345	G291-G295 PolarHBondContact O-N 2.91Å; I292-G295 PolarHBondContact O-N 3.02Å; L293-G295 VanDerWaalsContact C-N 3.33Å; L293-G295 PolarHBondContact O-N 2.96Å; G295-G299 PolarHBondContact O-N 3.04Å; G295-S341 WeakPolarHBondContact CA-O 3.38Å; G295-S341 WeakPolarHBondContact CA-OG 3.2Å; G295-S341 PolarHBondContact N-OG 3.21Å; G295-C345 VanDerWaalsContact O-CA 3.23Å; G295-C345 WeakPolarHBondContact O-CA 3.47Å; G295-C345 WeakPolarHBondContact O-CB 3.29Å
296	V	95.4	Very high	92.9	Very high	55 Å²	55	41 Å²	41	33%	0.333	22%	0.223	S	C	.	.	H	α-helix	trans	-62.8	-43.9	174.6	171.3	0	0	0	0	111.1	I292 L293 V294 G299 V300 V348	I292-V296 HydrophobicContact CG2-CG2 4.26Å; I292-V296 VanDerWaalsContact O-CG2 3.24Å; I292-V296 WeakPolarHBondContact O-CG2 3.11Å; I292-V296 PolarHBondContact O-N 3.42Å; L293-V296 PolarHBondContact O-N 3.26Å; V294-V296 PolarHBondContact O-N 3.42Å; V296-G299 PolarHBondContact O-N 3Å; V296-V300 HydrophobicContact CG1-CG2 4.45Å; V296-V300 WeakPolarHBondContact O-CB 3.44Å; V296-V300 WeakPolarHBondContact O-CG2 3.15Å; V296-V300 PolarHBondContact O-N 3.38Å; V296-V348 HydrophobicContact CG2-CG2 4.03Å
297	I	95.9	Very high	92.2	Very high	85 Å²	85	40.6 Å²	40.6	44%	0.436	21%	0.212	S	C	.	.	H	α-helix	trans	-59.7	-53.2	178.2	-68.6	162.8	0	0	0	110.2	L293 V294 G299 V300 L301	L293-I297 HydrophobicContact CD1-CD1 4.38Å; L293-I297 HydrophobicContact CG-CD1 4.18Å; L293-I297 WeakPolarHBondContact O-CG1 3.18Å; L293-I297 PolarHBondContact O-N 2.85Å; V294-I297 WeakPolarHBondContact O-CB 3.23Å; V294-I297 PolarHBondContact O-N 2.89Å; V294-I297 VanDerWaalsContact O-N 3.14Å; I297-G299 PolarHBondContact O-N 3.22Å; I297-V300 PolarHBondContact O-N 3.28Å; I297-L301 HydrophobicContact CG2-CD1 4.05Å; I297-L301 WeakPolarHBondContact O-CG 3.28Å; I297-L301 PolarHBondContact O-N 2.71Å
298	Y	95.4	Very high	91.5	Very high	61 Å²	61	45.3 Å²	45.3	24%	0.239	23%	0.23	C	C	.	.	H	α-helix	trans	-66.4	-34.4	179.1	-81	-84.5	0	0	0	113	V294 L301 G302 Y323 M326 A327 S330	V294-Y298 HydrophobicContact CG1-CD2 3.77Å; V294-Y298 HydrophobicContact CG1-CE2 3.89Å; V294-Y298 WeakPolarHBondContact O-CD2 3.29Å; V294-Y298 PolarHBondContact O-N 3.19Å; Y298-L301 PolarHBondContact O-N 3.28Å; Y298-G302 PolarHBondContact O-N 2.98Å; Y298-Y323 HydrophobicContact CD1-CD1 4.21Å; Y298-M326 HydrophobicContact CD1-CB 4.19Å; Y298-M326 HydrophobicContact CE1-CB 3.86Å; Y298-A327 HydrophobicContact CD2-CB 4Å; Y298-A327 HydrophobicContact CG-CB 3.79Å; Y298-S330 PolarHBondContact OH-OG 3.25Å; Y298-S330 VanDerWaalsContact OH-OG 3.08Å
299	G	93.6	Very high	90.7	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-64.9	-39.1	173.9	0	0	0	0	0	113	G295 V296 I297 A303	G295-G299 PolarHBondContact O-N 3.04Å; V296-G299 PolarHBondContact O-N 3Å; I297-G299 PolarHBondContact O-N 3.22Å; G299-A303 VanDerWaalsContact O-CB 3.25Å; G299-A303 WeakPolarHBondContact O-CB 3.3Å; G299-A303 PolarHBondContact O-N 2.89Å
300	V	91.8	Very high	89.3	Confident	41 Å²	41	42.3 Å²	42.3	25%	0.248	22%	0.218	C	C	.	.	H	α-helix	trans	-68.9	-42.2	172.7	171.1	0	0	0	0	111.1	V296 I297 A303 F304 V348 W549 L550	V296-V300 HydrophobicContact CG1-CG2 4.45Å; V296-V300 WeakPolarHBondContact O-CB 3.44Å; V296-V300 WeakPolarHBondContact O-CG2 3.15Å; V296-V300 PolarHBondContact O-N 3.38Å; I297-V300 PolarHBondContact O-N 3.28Å; V300-A303 PolarHBondContact O-N 3.48Å; V300-F304 VanDerWaalsContact O-CB 3.3Å; V300-F304 WeakPolarHBondContact O-CB 3.28Å; V300-F304 PolarHBondContact O-N 3.24Å; V300-V348 HydrophobicContact CG2-CG1 4Å; V300-W549 HydrophobicContact CG1-CZ3 3.92Å; V300-L550 HydrophobicContact CG1-CD2 4.37Å
301	L	92.6	Very high	88	Confident	78 Å²	78	49.6 Å²	49.6	41%	0.408	25%	0.248	S	C	.	.	H	α-helix	trans	-61.4	-46.3	175.5	-71.8	172	0	0	0	111.8	I297 Y298 F304 T305 Y323	I297-L301 HydrophobicContact CG2-CD1 4.05Å; I297-L301 WeakPolarHBondContact O-CG 3.28Å; I297-L301 PolarHBondContact O-N 2.71Å; Y298-L301 PolarHBondContact O-N 3.28Å; L301-F304 PolarHBondContact O-N 3.5Å; L301-T305 PolarHBondContact O-N 3.19Å; L301-T305 PolarHBondContact O-OG1 3.33Å; L301-T305 VanDerWaalsContact O-OG1 3.08Å; L301-Y323 HydrophobicContact CB-CD1 4.44Å; L301-Y323 HydrophobicContact CB-CE1 4.22Å
302	G	90.4	Very high	87	Confident	0 Å²	0	56.8 Å²	56.8	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-63.7	-42.2	176.5	0	0	0	0	0	112.8	Y298 F304 T305 S306 Y323	Y298-G302 PolarHBondContact O-N 2.98Å; G302-F304 VanDerWaalsContact C-N 3.35Å; G302-F304 PolarHBondContact O-N 3.24Å; G302-T305 PolarHBondContact O-N 3.5Å; G302-S306 PolarHBondContact O-N 3.4Å; G302-Y323 VanDerWaalsContact CA-CD2 3.42Å
303	A	87.6	Confident	86	Confident	0 Å²	0	60.8 Å²	60.8	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-62.7	-39.4	173.3	0	0	0	0	0	112.3	G299 V300 S306 Y352 V353 L550	G299-A303 VanDerWaalsContact O-CB 3.25Å; G299-A303 WeakPolarHBondContact O-CB 3.3Å; G299-A303 PolarHBondContact O-N 2.89Å; V300-A303 PolarHBondContact O-N 3.48Å; A303-S306 PolarHBondContact O-OG 2.85Å; A303-Y352 HydrophobicContact CB-CD2 4.09Å; A303-Y352 HydrophobicContact CB-CG 4.25Å; A303-V353 HydrophobicContact CB-CG2 4.4Å; A303-L550 HydrophobicContact CB-CD2 3.75Å
304	F	87.4	Confident	85.2	Confident	64 Å²	64	62.1 Å²	62.1	28%	0.281	30%	0.303	S	S	.	.	H	α-helix	trans	-65.7	-46.3	175	179.5	-101.5	0	0	0	111.9	V300 L301 G302 S306 R307 F308 W549 L550	V300-F304 VanDerWaalsContact O-CB 3.3Å; V300-F304 WeakPolarHBondContact O-CB 3.28Å; V300-F304 PolarHBondContact O-N 3.24Å; L301-F304 PolarHBondContact O-N 3.5Å; G302-F304 VanDerWaalsContact C-N 3.35Å; G302-F304 PolarHBondContact O-N 3.24Å; F304-S306 VanDerWaalsContact C-N 3.31Å; F304-S306 PolarHBondContact O-N 3.01Å; F304-R307 WeakPolarHBondContact O-CB 3.41Å; F304-R307 PolarHBondContact O-N 3.08Å; F304-R307 VanDerWaalsContact O-N 3.16Å; F304-F308 AromaticContact CD1-CE2 4Å; F304-F308 HydrophobicContact CD1-CE2 4Å; F304-F308 HydrophobicContact CD2-CE2 4.31Å; F304-F308 HydrophobicContact CE1-CD2 4.46Å; F304-F308 AromaticContact CE1-CE2 3.57Å; F304-F308 HydrophobicContact CE1-CE2 3.57Å; F304-F308 HydrophobicContact CE1-CZ 4.26Å; F304-F308 AromaticContact CE2-CE2 3.91Å; F304-F308 HydrophobicContact CE2-CE2 3.91Å; F304-F308 HydrophobicContact CE2-CZ 4.25Å; F304-F308 HydrophobicContact CG-CE2 4.36Å; F304-F308 AromaticContact CZ-CE2 3.53Å; F304-F308 HydrophobicContact CZ-CE2 3.53Å; F304-F308 AromaticContact CZ-CZ 3.84Å; F304-F308 HydrophobicContact CZ-CZ 3.84Å; F304-F308 WeakPolarHBondContact O-CD2 3.5Å; F304-W549 HydrophobicContact CD2-CH2 4.44Å; F304-W549 HydrophobicContact CD2-CZ2 4.15Å; F304-W549 HydrophobicContact CE2-CZ2 4.05Å; F304-L550 HydrophobicContact CB-CD2 3.85Å
305	T	87.3	Confident	84.6	Confident	27 Å²	27	64.7 Å²	64.7	17%	0.166	32%	0.315	C	S	.	.	H	α-helix	trans	-62.5	-37.7	178	-59.8	0	0	0	0	111.9	L301 G302 R307 F308 T309 F319 Y323	L301-T305 PolarHBondContact O-N 3.19Å; L301-T305 PolarHBondContact O-OG1 3.33Å; L301-T305 VanDerWaalsContact O-OG1 3.08Å; G302-T305 PolarHBondContact O-N 3.5Å; T305-R307 PolarHBondContact O-N 2.85Å; T305-R307 VanDerWaalsContact O-N 3.08Å; T305-F308 PolarHBondContact O-N 2.83Å; T305-T309 PolarHBondContact O-N 3.35Å; T305-T309 PolarHBondContact O-OG1 2.95Å; T305-T309 VanDerWaalsContact O-OG1 3.1Å; T305-F319 HydrophobicContact CG2-CD1 4.06Å; T305-F319 HydrophobicContact CG2-CD2 4.29Å; T305-F319 HydrophobicContact CG2-CE1 4.06Å; T305-F319 HydrophobicContact CG2-CE2 4.27Å; T305-F319 HydrophobicContact CG2-CG 4.19Å; T305-F319 HydrophobicContact CG2-CZ 4.16Å; T305-Y323 HydrophobicContact CG2-CE2 3.92Å; T305-Y323 PolarHBondContact OG1-OH 3.42Å
306	S	84	Confident	84	Confident	9 Å²	9	65.1 Å²	65.1	6%	0.063	32%	0.317	C	S	.	.	H	α-helix	trans	-57.9	-24.8	177	77.8	0	0	0	0	114.1	G302 A303 F304 F308 N356	G302-S306 PolarHBondContact O-N 3.4Å; A303-S306 PolarHBondContact O-OG 2.85Å; F304-S306 VanDerWaalsContact C-N 3.31Å; F304-S306 PolarHBondContact O-N 3.01Å; S306-F308 VanDerWaalsContact C-N 3.33Å; S306-F308 PolarHBondContact O-N 3.43Å; S306-N356 PolarHBondContact OG-ND2 3.4Å
307	R	79.4	Confident	83.6	Confident	77 Å²	77	63.2 Å²	63.2	29%	0.291	31%	0.305	S	S	.	.	H	α-helix	trans	-62.3	-39.1	174.5	-175.2	-179.6	164.2	140.4	4.7	112	F304 T305 S310 K548 W549 A552	F304-R307 WeakPolarHBondContact O-CB 3.41Å; F304-R307 PolarHBondContact O-N 3.08Å; F304-R307 VanDerWaalsContact O-N 3.16Å; T305-R307 PolarHBondContact O-N 2.85Å; T305-R307 VanDerWaalsContact O-N 3.08Å; R307-S310 PolarHBondContact O-OG 3.48Å; R307-K548 PolarHBondContact NH1-O 2.85Å; R307-W549 PolarHBondContact NH1-O 3.02Å; R307-A552 HydrophobicContact CG-CB 4.06Å
308	F	79.5	Confident	83.2	Confident	128 Å²	128	64.2 Å²	64.2	56%	0.561	31%	0.311	S	S	*	.	H	α-helix	trans	-86.8	-20.5	-174.8	-60.5	-82.8	0	0	0	113.2	F304 T305 S306 S310	F304-F308 AromaticContact CD1-CE2 4Å; F304-F308 HydrophobicContact CD1-CE2 4Å; F304-F308 HydrophobicContact CD2-CE2 4.31Å; F304-F308 HydrophobicContact CE1-CD2 4.46Å; F304-F308 AromaticContact CE1-CE2 3.57Å; F304-F308 HydrophobicContact CE1-CE2 3.57Å; F304-F308 HydrophobicContact CE1-CZ 4.26Å; F304-F308 AromaticContact CE2-CE2 3.91Å; F304-F308 HydrophobicContact CE2-CE2 3.91Å; F304-F308 HydrophobicContact CE2-CZ 4.25Å; F304-F308 HydrophobicContact CG-CE2 4.36Å; F304-F308 AromaticContact CZ-CE2 3.53Å; F304-F308 HydrophobicContact CZ-CE2 3.53Å; F304-F308 AromaticContact CZ-CZ 3.84Å; F304-F308 HydrophobicContact CZ-CZ 3.84Å; F304-F308 WeakPolarHBondContact O-CD2 3.5Å; T305-F308 PolarHBondContact O-N 2.83Å; S306-F308 VanDerWaalsContact C-N 3.33Å; S306-F308 PolarHBondContact O-N 3.43Å; F308-S310 PolarHBondContact O-N 3.4Å; F308-S310 VanDerWaalsContact O-N 3.12Å
309	T	74.7	Confident	82.9	Confident	10 Å²	10	63.9 Å²	63.9	6%	0.061	31%	0.311	C	S	.	.	G	3₁₀ helix	trans	-72.9	-1.1	-177	-38.1	0	0	0	0	114.2	T305 H311 F312 I315 E316 F319	T305-T309 PolarHBondContact O-N 3.35Å; T305-T309 PolarHBondContact O-OG1 2.95Å; T305-T309 VanDerWaalsContact O-OG1 3.1Å; T309-H311 PolarHBondContact O-N 2.86Å; T309-F312 CarbonylContact O-C 3.54Å; T309-F312 PolarHBondContact O-N 3.04Å; T309-I315 HydrophobicContact CG2-CB 4.3Å; T309-E316 HydrophobicContact CG2-CB 4.43Å; T309-E316 HydrophobicContact CG2-CG 3.7Å; T309-F319 HydrophobicContact CG2-CD2 3.98Å; T309-F319 HydrophobicContact CG2-CE2 3.8Å
310	S	66.2	Low	82.7	Confident	47 Å²	47	63.9 Å²	63.9	33%	0.329	31%	0.311	S	S	.	.	G	3₁₀ helix	trans	-49.3	-27.6	-175.1	-64.7	0	0	0	0	116	R307 F308	R307-S310 PolarHBondContact O-OG 3.48Å; F308-S310 PolarHBondContact O-N 3.4Å; F308-S310 VanDerWaalsContact O-N 3.12Å
311	H	66.9	Low	82.7	Confident	167 Å²	167	63.2 Å²	63.2	77%	0.773	31%	0.305	S	S	*	.	G	3₁₀ helix	trans	-84.7	-25.7	177.3	-67.8	-80.9	0	0	0	114.1	T309	T309-H311 PolarHBondContact O-N 2.86Å
312	F	74.3	Confident	82.7	Confident	150 Å²	150	63.4 Å²	63.4	66%	0.658	31%	0.306	S	S	*	.			trans	-121.6	67.8	-171.7	-65.5	-73.3	0	0	0	112.3	T309 V314 I315	T309-F312 CarbonylContact O-C 3.54Å; T309-F312 PolarHBondContact O-N 3.04Å; F312-V314 PolarHBondContact O-N 2.86Å; F312-I315 HydrophobicContact CB-CD1 4.02Å; F312-I315 HydrophobicContact CB-CG1 4.32Å; F312-I315 PolarHBondContact O-N 3.16Å
313	R	73.7	Confident	82.9	Confident	152 Å²	152	66 Å²	66	57%	0.574	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	-17.5	-169	-52.6	-176.5	-162.7	164.1	10.1	116.2	I315	R313-I315 VanDerWaalsContact C-N 3.33Å
314	V	80	Confident	83.2	Confident	137 Å²	137	66 Å²	66	83%	0.83	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	-25.8	178.1	-175.5	0	0	0	0	111.7	F312 P317	F312-V314 PolarHBondContact O-N 2.86Å; V314-P317 WeakPolarHBondContact O-CD 3.39Å
315	I	83.9	Confident	83.6	Confident	70 Å²	70	66.2 Å²	66.2	36%	0.359	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.2	-18.4	-177.5	-45.3	179	0	0	0	111.1	T309 F312 R313 L318 F319	T309-I315 HydrophobicContact CG2-CB 4.3Å; F312-I315 HydrophobicContact CB-CD1 4.02Å; F312-I315 HydrophobicContact CB-CG1 4.32Å; F312-I315 PolarHBondContact O-N 3.16Å; R313-I315 VanDerWaalsContact C-N 3.33Å; I315-L318 HydrophobicContact CG2-CB 4.36Å; I315-L318 HydrophobicContact CG2-CD2 4.31Å; I315-L318 WeakPolarHBondContact O-CB 3.29Å; I315-L318 PolarHBondContact O-N 2.79Å; I315-F319 HydrophobicContact CB-CE2 4.2Å; I315-F319 HydrophobicContact CG2-CD2 3.91Å; I315-F319 HydrophobicContact CG2-CE2 3.44Å; I315-F319 VanDerWaalsContact CG2-CE2 3.44Å; I315-F319 HydrophobicContact CG2-CZ 3.88Å; I315-F319 WeakPolarHBondContact O-CD2 3.35Å; I315-F319 PolarHBondContact O-N 3.36Å
316	E	83.9	Confident	83.9	Confident	10 Å²	10	68.5 Å²	68.5	5%	0.047	33%	0.325	C	S	.	.	H	α-helix	trans	-48.9	-46.4	178.4	-70.7	173.8	-167.8	0	0	113.6	T309 I357 S358 S361	T309-E316 HydrophobicContact CG2-CB 4.43Å; T309-E316 HydrophobicContact CG2-CG 3.7Å; E316-I357 HydrophobicContact CB-CD1 3.82Å; E316-I357 HydrophobicContact CB-CG1 4.09Å; E316-I357 HydrophobicContact CG-CG1 4.23Å; E316-I357 WeakPolarHBondContact OE2-CG2 3.24Å; E316-S358 PolarHBondContact OE2-N 3.3Å; E316-S361 VanDerWaalsContact CB-OG 3.29Å; E316-S361 WeakPolarHBondContact CB-OG 3.34Å; E316-S361 WeakPolarHBondContact OE2-CB 3.4Å; E316-S361 PolarHBondContact OE2-OG 2.94Å
317	P	86.5	Confident	84.5	Confident	14 Å²	14	68 Å²	68	9%	0.091	32%	0.322	C	S	.	.	H	α-helix	trans	-66.7	-40	176.1	-20.3	35.3	0	0	0	112.8	V314 F319 V320 F321 T364 I365	V314-P317 WeakPolarHBondContact O-CD 3.39Å; P317-F319 VanDerWaalsContact C-N 3.26Å; P317-F319 PolarHBondContact O-N 2.84Å; P317-V320 WeakPolarHBondContact O-CB 3.25Å; P317-V320 PolarHBondContact O-N 3Å; P317-F321 HydrophobicContact CB-CE2 3.91Å; P317-F321 WeakPolarHBondContact O-CD2 3.47Å; P317-F321 VanDerWaalsContact O-CE2 3.24Å; P317-F321 WeakPolarHBondContact O-CE2 3.3Å; P317-F321 PolarHBondContact O-N 3.06Å; P317-T364 HydrophobicContact CG-CG2 4.23Å; P317-I365 HydrophobicContact CB-CD1 4.36Å; P317-I365 HydrophobicContact CB-CG1 3.59Å; P317-I365 HydrophobicContact CG-CD1 4.47Å; P317-I365 HydrophobicContact CG-CG1 3.95Å
318	L	87.8	Confident	85.3	Confident	107 Å²	107	64.5 Å²	64.5	56%	0.56	31%	0.309	S	S	*	.	H	α-helix	trans	-58.6	-38.9	-176.5	-173.8	66.7	0	0	0	111.8	I315 V320 F321 L322	I315-L318 HydrophobicContact CG2-CB 4.36Å; I315-L318 HydrophobicContact CG2-CD2 4.31Å; I315-L318 WeakPolarHBondContact O-CB 3.29Å; I315-L318 PolarHBondContact O-N 2.79Å; L318-V320 VanDerWaalsContact C-N 3.35Å; L318-V320 PolarHBondContact O-N 3.31Å; L318-F321 PolarHBondContact O-N 2.91Å; L318-L322 VanDerWaalsContact O-CB 3.32Å; L318-L322 WeakPolarHBondContact O-CB 3.46Å; L318-L322 PolarHBondContact O-N 3.24Å
319	F	89.1	Confident	85.9	Confident	53 Å²	53	60.9 Å²	60.9	23%	0.232	30%	0.295	C	S	.	.	H	α-helix	trans	-64.1	-35.7	174.7	-72.1	-57.9	0	0	0	113.1	T305 T309 I315 P317 L322 Y323	T305-F319 HydrophobicContact CG2-CD1 4.06Å; T305-F319 HydrophobicContact CG2-CD2 4.29Å; T305-F319 HydrophobicContact CG2-CE1 4.06Å; T305-F319 HydrophobicContact CG2-CE2 4.27Å; T305-F319 HydrophobicContact CG2-CG 4.19Å; T305-F319 HydrophobicContact CG2-CZ 4.16Å; T309-F319 HydrophobicContact CG2-CD2 3.98Å; T309-F319 HydrophobicContact CG2-CE2 3.8Å; I315-F319 HydrophobicContact CB-CE2 4.2Å; I315-F319 HydrophobicContact CG2-CD2 3.91Å; I315-F319 HydrophobicContact CG2-CE2 3.44Å; I315-F319 VanDerWaalsContact CG2-CE2 3.44Å; I315-F319 HydrophobicContact CG2-CZ 3.88Å; I315-F319 WeakPolarHBondContact O-CD2 3.35Å; I315-F319 PolarHBondContact O-N 3.36Å; P317-F319 VanDerWaalsContact C-N 3.26Å; P317-F319 PolarHBondContact O-N 2.84Å; F319-L322 PolarHBondContact O-N 2.83Å; F319-Y323 HydrophobicContact CB-CD2 4.09Å; F319-Y323 HydrophobicContact CB-CE2 4.17Å; F319-Y323 HydrophobicContact CD1-CD2 4.37Å; F319-Y323 AromaticContact CD1-CE2 3.77Å; F319-Y323 HydrophobicContact CD1-CE2 3.77Å; F319-Y323 HydrophobicContact CG-CE2 4.29Å; F319-Y323 WeakPolarHBondContact O-CB 3.35Å; F319-Y323 WeakPolarHBondContact O-CD2 3.47Å; F319-Y323 PolarHBondContact O-N 2.84Å
320	V	90	Very high	86.9	Confident	1 Å²	1	61.5 Å²	61.5	1%	0.006	30%	0.3	C	S	.	.	H	α-helix	trans	-59.5	-50.8	175.3	-176.4	0	0	0	0	110.1	Y161 P317 L318 S324 M349 V353 I357 I365	Y161-V320 HydrophobicContact CD2-CG1 4.22Å; Y161-V320 HydrophobicContact CE2-CG1 3.9Å; P317-V320 WeakPolarHBondContact O-CB 3.25Å; P317-V320 PolarHBondContact O-N 3Å; L318-V320 VanDerWaalsContact C-N 3.35Å; L318-V320 PolarHBondContact O-N 3.31Å; V320-S324 WeakPolarHBondContact O-CB 3.38Å; V320-S324 PolarHBondContact O-N 3.29Å; V320-S324 PolarHBondContact O-OG 3.47Å; V320-M349 HydrophobicContact CB-CE 4.22Å; V320-M349 HydrophobicContact CB-SD 4.47Å; V320-M349 HydrophobicContact CG1-SD 4.14Å; V320-M349 HydrophobicContact CG2-CE 3.97Å; V320-V353 HydrophobicContact CG2-CG1 4.09Å; V320-I357 HydrophobicContact CG2-CD1 4.49Å; V320-I365 HydrophobicContact CG2-CD1 3.83Å; V320-I365 HydrophobicContact CG2-CG1 4.38Å
321	F	91.4	Very high	88.3	Confident	26 Å²	26	59.3 Å²	59.3	11%	0.114	28%	0.284	C	S	.	.	H	α-helix	trans	-63.7	-47.3	178.9	-57.7	-64.7	0	0	0	112.3	L157 P317 L318 S324 Y325 F368 L369	L157-F321 HydrophobicContact CD2-CD1 4.09Å; P317-F321 HydrophobicContact CB-CE2 3.91Å; P317-F321 WeakPolarHBondContact O-CD2 3.47Å; P317-F321 VanDerWaalsContact O-CE2 3.24Å; P317-F321 WeakPolarHBondContact O-CE2 3.3Å; P317-F321 PolarHBondContact O-N 3.06Å; L318-F321 PolarHBondContact O-N 2.91Å; F321-S324 PolarHBondContact O-N 3.41Å; F321-Y325 VanDerWaalsContact O-CB 3.3Å; F321-Y325 WeakPolarHBondContact O-CB 3.35Å; F321-Y325 PolarHBondContact O-N 3.05Å; F321-F368 HydrophobicContact CD1-CD1 4.42Å; F321-F368 HydrophobicContact CD1-CE1 4.19Å; F321-F368 HydrophobicContact CD2-CD1 4.3Å; F321-F368 AromaticContact CD2-CE1 4Å; F321-F368 HydrophobicContact CD2-CE1 4Å; F321-F368 AromaticContact CE1-CD1 3.65Å; F321-F368 HydrophobicContact CE1-CD1 3.65Å; F321-F368 AromaticContact CE1-CE1 3.86Å; F321-F368 HydrophobicContact CE1-CE1 3.86Å; F321-F368 AromaticContact CE2-CD1 3.54Å; F321-F368 HydrophobicContact CE2-CD1 3.54Å; F321-F368 AromaticContact CE2-CE1 3.69Å; F321-F368 HydrophobicContact CE2-CE1 3.69Å; F321-F368 HydrophobicContact CE2-CG 4.49Å; F321-F368 HydrophobicContact CG-CE1 4.29Å; F321-F368 HydrophobicContact CZ-CB 4.5Å; F321-F368 AromaticContact CZ-CD1 3.21Å; F321-F368 HydrophobicContact CZ-CD1 3.21Å; F321-F368 AromaticContact CZ-CE1 3.68Å; F321-F368 HydrophobicContact CZ-CE1 3.68Å; F321-F368 HydrophobicContact CZ-CG 4.24Å; F321-L369 HydrophobicContact CD1-CD2 4.34Å; F321-L369 HydrophobicContact CE1-CD2 3.56Å; F321-L369 HydrophobicContact CE1-CG 3.64Å; F321-L369 HydrophobicContact CZ-CD2 4.47Å; F321-L369 HydrophobicContact CZ-CG 4.07Å
322	L	92.6	Very high	89.4	Confident	82 Å²	82	54.6 Å²	54.6	43%	0.429	26%	0.263	S	S	.	.	H	α-helix	trans	-67.7	-44.6	-173.8	-172	62.9	0	0	0	112.1	L318 F319 M326	L318-L322 VanDerWaalsContact O-CB 3.32Å; L318-L322 WeakPolarHBondContact O-CB 3.46Å; L318-L322 PolarHBondContact O-N 3.24Å; F319-L322 PolarHBondContact O-N 2.83Å; L322-M326 HydrophobicContact CD1-CE 3.83Å; L322-M326 HydrophobicContact CD1-CG 4.28Å; L322-M326 HydrophobicContact CG-CG 4.43Å; L322-M326 VanDerWaalsContact O-CB 3.28Å; L322-M326 WeakPolarHBondContact O-CB 3.2Å; L322-M326 WeakPolarHBondContact O-CG 3.31Å; L322-M326 PolarHBondContact O-N 3.29Å
323	Y	94.6	Very high	90.2	Very high	56 Å²	56	52.6 Å²	52.6	22%	0.22	26%	0.263	C	S	.	.	H	α-helix	trans	-67	-39.1	178.2	-78.4	-64.9	0	0	0	112.3	Y298 L301 G302 T305 F319 A327	Y298-Y323 HydrophobicContact CD1-CD1 4.21Å; L301-Y323 HydrophobicContact CB-CD1 4.44Å; L301-Y323 HydrophobicContact CB-CE1 4.22Å; G302-Y323 VanDerWaalsContact CA-CD2 3.42Å; T305-Y323 HydrophobicContact CG2-CE2 3.92Å; T305-Y323 PolarHBondContact OG1-OH 3.42Å; F319-Y323 HydrophobicContact CB-CD2 4.09Å; F319-Y323 HydrophobicContact CB-CE2 4.17Å; F319-Y323 HydrophobicContact CD1-CD2 4.37Å; F319-Y323 AromaticContact CD1-CE2 3.77Å; F319-Y323 HydrophobicContact CD1-CE2 3.77Å; F319-Y323 HydrophobicContact CG-CE2 4.29Å; F319-Y323 WeakPolarHBondContact O-CB 3.35Å; F319-Y323 WeakPolarHBondContact O-CD2 3.47Å; F319-Y323 PolarHBondContact O-N 2.84Å; Y323-A327 WeakPolarHBondContact O-CB 3.31Å; Y323-A327 PolarHBondContact O-N 2.93Å
324	S	94.9	Very high	91	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-67.6	-42.4	176.3	-66.6	0	0	0	0	112.6	L157 V320 F321 A327 Y328 L342 C345	L157-S324 WeakPolarHBondContact CD1-OG 3.48Å; V320-S324 WeakPolarHBondContact O-CB 3.38Å; V320-S324 PolarHBondContact O-N 3.29Å; V320-S324 PolarHBondContact O-OG 3.47Å; F321-S324 PolarHBondContact O-N 3.41Å; S324-A327 WeakPolarHBondContact O-CB 3.29Å; S324-A327 PolarHBondContact O-N 3.11Å; S324-Y328 PolarHBondContact O-N 2.94Å; S324-Y328 VanDerWaalsContact O-N 3.13Å; S324-L342 VanDerWaalsContact O-CD1 3.24Å; S324-L342 WeakPolarHBondContact O-CD1 3.49Å; S324-C345 PolarHBondContact OG-SG 3.28Å; S324-C345 VanDerWaalsContact OG-SG 3.41Å
325	Y	94.4	Very high	91.5	Very high	67 Å²	67	53.4 Å²	53.4	26%	0.263	26%	0.262	S	S	.	.	H	α-helix	trans	-68.1	-36.9	175.8	-173.1	-119.5	0	0	0	112.5	L149 P153 F321 A327 Y328 L329	L149-Y325 WeakPolarHBondContact O-CE2 3.32Å; P153-Y325 HydrophobicContact CB-CD2 4.49Å; F321-Y325 VanDerWaalsContact O-CB 3.3Å; F321-Y325 WeakPolarHBondContact O-CB 3.35Å; F321-Y325 PolarHBondContact O-N 3.05Å; Y325-A327 VanDerWaalsContact C-N 3.34Å; Y325-A327 PolarHBondContact O-N 2.89Å; Y325-Y328 HydrophobicContact CD2-CD1 4.5Å; Y325-Y328 HydrophobicContact CE2-CD1 4.33Å; Y325-Y328 WeakPolarHBondContact O-CB 3.48Å; Y325-Y328 PolarHBondContact O-N 3.2Å; Y325-L329 HydrophobicContact CD1-CD1 3.95Å; Y325-L329 HydrophobicContact CD1-CG 4.37Å; Y325-L329 HydrophobicContact CE1-CD1 3.46Å; Y325-L329 VanDerWaalsContact CE1-CD1 3.46Å; Y325-L329 HydrophobicContact CE1-CD2 4.5Å; Y325-L329 HydrophobicContact CE1-CG 4.01Å; Y325-L329 HydrophobicContact CE2-CD2 4.31Å; Y325-L329 HydrophobicContact CE2-CG 4.24Å; Y325-L329 PolarHBondContact O-N 3.45Å
326	M	95	Very high	91.9	Very high	75 Å²	75	51.6 Å²	51.6	37%	0.369	25%	0.253	S	S	.	.	H	α-helix	trans	-65.3	-36	172.3	-71.1	-68.6	158.6	0	0	112.1	Y298 L322 Y328 L329 S330	Y298-M326 HydrophobicContact CD1-CB 4.19Å; Y298-M326 HydrophobicContact CE1-CB 3.86Å; L322-M326 HydrophobicContact CD1-CE 3.83Å; L322-M326 HydrophobicContact CD1-CG 4.28Å; L322-M326 HydrophobicContact CG-CG 4.43Å; L322-M326 VanDerWaalsContact O-CB 3.28Å; L322-M326 WeakPolarHBondContact O-CB 3.2Å; L322-M326 WeakPolarHBondContact O-CG 3.31Å; L322-M326 PolarHBondContact O-N 3.29Å; M326-Y328 VanDerWaalsContact C-N 3.31Å; M326-Y328 PolarHBondContact O-N 3.49Å; M326-L329 PolarHBondContact O-N 2.84Å; M326-S330 VanDerWaalsContact O-CB 3.24Å; M326-S330 WeakPolarHBondContact O-CB 3.3Å; M326-S330 PolarHBondContact O-N 3.16Å; M326-S330 PolarHBondContact O-OG 2.9Å
327	A	96.1	Very high	92.3	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-61.5	-39.9	173	0	0	0	0	0	112.2	Y298 Y323 S324 Y325 A331 S341 C345	Y298-A327 HydrophobicContact CD2-CB 4Å; Y298-A327 HydrophobicContact CG-CB 3.79Å; Y323-A327 WeakPolarHBondContact O-CB 3.31Å; Y323-A327 PolarHBondContact O-N 2.93Å; S324-A327 WeakPolarHBondContact O-CB 3.29Å; S324-A327 PolarHBondContact O-N 3.11Å; Y325-A327 VanDerWaalsContact C-N 3.34Å; Y325-A327 PolarHBondContact O-N 2.89Å; A327-A331 WeakPolarHBondContact O-CB 3.32Å; A327-A331 PolarHBondContact O-N 3.15Å; A327-S341 VanDerWaalsContact C-OG 3.27Å; A327-S341 WeakPolarHBondContact O-CB 3.48Å; A327-S341 PolarHBondContact O-OG 2.97Å; A327-C345 HydrophobicContact CB-CB 3.98Å
328	Y	94.9	Very high	92.7	Very high	3 Å²	3	50.9 Å²	50.9	1%	0.012	25%	0.249	C	C	.	.	H	α-helix	trans	-63.8	-58.3	174.3	177.6	-99	0	0	0	110.7	F148 L149 P153 S324 Y325 M326 S330 A331 E332 G338 L342	F148-Y328 PolarHBondContact O-OH 2.91Å; L149-Y328 HydrophobicContact CD2-CE1 4.08Å; P153-Y328 HydrophobicContact CG-CD1 4.1Å; P153-Y328 HydrophobicContact CG-CE1 4.12Å; P153-Y328 HydrophobicContact CG-CG 4.39Å; S324-Y328 PolarHBondContact O-N 2.94Å; S324-Y328 VanDerWaalsContact O-N 3.13Å; Y325-Y328 HydrophobicContact CD2-CD1 4.5Å; Y325-Y328 HydrophobicContact CE2-CD1 4.33Å; Y325-Y328 WeakPolarHBondContact O-CB 3.48Å; Y325-Y328 PolarHBondContact O-N 3.2Å; M326-Y328 VanDerWaalsContact C-N 3.31Å; M326-Y328 PolarHBondContact O-N 3.49Å; Y328-S330 VanDerWaalsContact C-N 3.34Å; Y328-S330 PolarHBondContact O-N 3.28Å; Y328-A331 PolarHBondContact O-N 3.2Å; Y328-A331 VanDerWaalsContact O-N 3.11Å; Y328-E332 HydrophobicContact CD1-CG 4.42Å; Y328-E332 HydrophobicContact CE1-CG 3.92Å; Y328-E332 HydrophobicContact CE2-CG 4.21Å; Y328-E332 VanDerWaalsContact CE2-OE1 3.27Å; Y328-E332 WeakPolarHBondContact CE2-OE1 3.22Å; Y328-E332 WeakPolarHBondContact O-CG 3.43Å; Y328-E332 PolarHBondContact O-N 3.4Å; Y328-E332 VanDerWaalsContact O-N 3.08Å; Y328-E332 PolarHBondContact OH-OE1 3.18Å; Y328-G338 VanDerWaalsContact CD2-C 3.42Å; Y328-G338 WeakPolarHBondContact CD2-O 3.39Å; Y328-L342 HydrophobicContact CD2-CD2 4.43Å
329	L	93.9	Very high	92.9	Very high	52 Å²	52	46 Å²	46	27%	0.272	22%	0.223	S	C	.	.	H	α-helix	trans	-59.4	-39.6	-178.8	-69.3	-177.5	0	0	0	113.5	L149 Y325 M326 A331 E332 V333	L149-L329 HydrophobicContact CD2-CD2 4.3Å; Y325-L329 HydrophobicContact CD1-CD1 3.95Å; Y325-L329 HydrophobicContact CD1-CG 4.37Å; Y325-L329 HydrophobicContact CE1-CD1 3.46Å; Y325-L329 VanDerWaalsContact CE1-CD1 3.46Å; Y325-L329 HydrophobicContact CE1-CD2 4.5Å; Y325-L329 HydrophobicContact CE1-CG 4.01Å; Y325-L329 HydrophobicContact CE2-CD2 4.31Å; Y325-L329 HydrophobicContact CE2-CG 4.24Å; Y325-L329 PolarHBondContact O-N 3.45Å; M326-L329 PolarHBondContact O-N 2.84Å; L329-A331 VanDerWaalsContact C-N 3.34Å; L329-E332 PolarHBondContact O-N 3Å; L329-V333 WeakPolarHBondContact O-CG2 3.3Å; L329-V333 PolarHBondContact O-N 2.82Å
330	S	95	Very high	93.1	Very high	23 Å²	23	44.1 Å²	44.1	16%	0.161	22%	0.216	C	C	.	.	H	α-helix	trans	-68.1	-33.8	178	-66.4	0	0	0	0	112.5	Y298 M326 Y328 F334	Y298-S330 PolarHBondContact OH-OG 3.25Å; Y298-S330 VanDerWaalsContact OH-OG 3.08Å; M326-S330 VanDerWaalsContact O-CB 3.24Å; M326-S330 WeakPolarHBondContact O-CB 3.3Å; M326-S330 PolarHBondContact O-N 3.16Å; M326-S330 PolarHBondContact O-OG 2.9Å; Y328-S330 VanDerWaalsContact C-N 3.34Å; Y328-S330 PolarHBondContact O-N 3.28Å; S330-F334 WeakPolarHBondContact O-CD2 3.37Å; S330-F334 PolarHBondContact O-N 3.03Å
331	A	94.6	Very high	93.4	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-67.8	-43.8	173.4	0	0	0	0	0	111.4	V294 A327 Y328 L329 V333 F334 H335 L336	V294-A331 HydrophobicContact CG1-CB 4.39Å; A327-A331 WeakPolarHBondContact O-CB 3.32Å; A327-A331 PolarHBondContact O-N 3.15Å; Y328-A331 PolarHBondContact O-N 3.2Å; Y328-A331 VanDerWaalsContact O-N 3.11Å; L329-A331 VanDerWaalsContact C-N 3.34Å; A331-V333 VanDerWaalsContact C-N 3.33Å; A331-V333 PolarHBondContact O-N 3.31Å; A331-F334 CarbonylContact O-C 3.58Å; A331-F334 PolarHBondContact O-N 3.31Å; A331-F334 VanDerWaalsContact O-N 3.08Å; A331-H335 PolarHBondContact O-N 2.83Å; A331-L336 CarbonylContact C-O 3.54Å; A331-L336 HydrophobicContact CB-CB 4.16Å; A331-L336 PolarHBondContact O-N 2.98Å
332	E	90.5	Very high	93.6	Very high	68 Å²	68	43 Å²	43	32%	0.318	21%	0.211	S	C	.	.	H	α-helix	trans	-57.9	-42.3	174.1	-63.5	-67.3	162.6	0	0	112	Y328 L329 F334 H335	Y328-E332 HydrophobicContact CD1-CG 4.42Å; Y328-E332 HydrophobicContact CE1-CG 3.92Å; Y328-E332 HydrophobicContact CE2-CG 4.21Å; Y328-E332 VanDerWaalsContact CE2-OE1 3.27Å; Y328-E332 WeakPolarHBondContact CE2-OE1 3.22Å; Y328-E332 WeakPolarHBondContact O-CG 3.43Å; Y328-E332 PolarHBondContact O-N 3.4Å; Y328-E332 VanDerWaalsContact O-N 3.08Å; Y328-E332 PolarHBondContact OH-OE1 3.18Å; L329-E332 PolarHBondContact O-N 3Å; E332-F334 PolarHBondContact O-N 3.37Å; E332-H335 PolarHBondContact O-N 2.69Å
333	V	92.3	Very high	93.7	Very high	109 Å²	109	39.5 Å²	39.5	66%	0.661	19%	0.193	S	C	*	.	H	α-helix	trans	-61.2	-29.4	175.9	166.7	0	0	0	0	113.2	L329 A331	L329-V333 WeakPolarHBondContact O-CG2 3.3Å; L329-V333 PolarHBondContact O-N 2.82Å; A331-V333 VanDerWaalsContact C-N 3.33Å; A331-V333 PolarHBondContact O-N 3.31Å
334	F	90.7	Very high	93.6	Very high	137 Å²	137	37.5 Å²	37.5	60%	0.601	19%	0.187	S	C	*	.	T	Hydrogen-bonded Turn	trans	-94.5	8.9	176.4	-67.1	-57.3	0	0	0	113.5	S330 A331 E332 L336	S330-F334 WeakPolarHBondContact O-CD2 3.37Å; S330-F334 PolarHBondContact O-N 3.03Å; A331-F334 CarbonylContact O-C 3.58Å; A331-F334 PolarHBondContact O-N 3.31Å; A331-F334 VanDerWaalsContact O-N 3.08Å; E332-F334 PolarHBondContact O-N 3.37Å; F334-L336 HydrophobicContact CB-CD1 3.78Å; F334-L336 HydrophobicContact CB-CG 3.82Å; F334-L336 PolarHBondContact O-N 2.86Å
335	H	88.9	Confident	93.7	Very high	168 Å²	168	37.5 Å²	37.5	78%	0.778	19%	0.187	S	C	*	.	T	Hydrogen-bonded Turn	trans	53.3	32.7	-171.2	-60.3	-84.7	0	0	0	113.2	A331 E332	A331-H335 PolarHBondContact O-N 2.83Å; E332-H335 PolarHBondContact O-N 2.69Å
336	L	92.6	Very high	93.6	Very high	33 Å²	33	34.3 Å²	34.3	17%	0.173	18%	0.175	C	C	.	.	S	Bend	trans	-99.2	162.5	175.2	-61.3	175.5	0	0	0	110.2	V294 A331 F334 G338	V294-L336 HydrophobicContact CG2-CD1 3.9Å; A331-L336 CarbonylContact C-O 3.54Å; A331-L336 HydrophobicContact CB-CB 4.16Å; A331-L336 PolarHBondContact O-N 2.98Å; F334-L336 HydrophobicContact CB-CD1 3.78Å; F334-L336 HydrophobicContact CB-CG 3.82Å; F334-L336 PolarHBondContact O-N 2.86Å; L336-G338 PolarHBondContact O-N 3.08Å
337	S	93.6	Very high	93.4	Very high	8 Å²	8	32.3 Å²	32.3	6%	0.056	17%	0.167	C	C	.	.			trans	-66	101.6	-179	-176.6	0	0	0	0	112.1	V287 I339 M340 S341	V287-S337 PolarHBondContact O-N 3.18Å; V287-S337 VanDerWaalsContact O-N 3.14Å; S337-I339 VanDerWaalsContact C-N 3.29Å; S337-I339 PolarHBondContact O-N 2.87Å; S337-M340 PolarHBondContact O-N 3.34Å; S337-M340 WeakPolarHBondContact OG-CG 3.45Å; S337-M340 PolarHBondContact OG-N 3.09Å; S337-S341 PolarHBondContact O-N 3.17Å
338	G	93.3	Very high	93.2	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.01	18%	0.176	C	C	.	.	H	α-helix	trans	-56.7	-42.3	174.9	0	0	0	0	0	112.5	Y328 L336 S341 L342	Y328-G338 VanDerWaalsContact CD2-C 3.42Å; Y328-G338 WeakPolarHBondContact CD2-O 3.39Å; L336-G338 PolarHBondContact O-N 3.08Å; G338-S341 WeakPolarHBondContact O-CB 3.31Å; G338-S341 PolarHBondContact O-N 3.03Å; G338-L342 WeakPolarHBondContact O-CB 3.43Å; G338-L342 PolarHBondContact O-N 2.93Å
339	I	93.1	Very high	93	Very high	3 Å²	3	33.8 Å²	33.8	2%	0.015	18%	0.176	C	C	.	.	H	α-helix	trans	-62.1	-48.2	178.6	-57.1	-174.4	0	0	0	111.2	L152 I156 A254 V257 S337 S341 L342 I343	L152-I339 HydrophobicContact CD1-CD1 4.21Å; L152-I339 HydrophobicContact CD2-CD1 4.16Å; L152-I339 HydrophobicContact CD2-CG1 4.09Å; I156-I339 HydrophobicContact CD1-CB 4.41Å; I156-I339 HydrophobicContact CD1-CD1 4.32Å; I156-I339 HydrophobicContact CD1-CG1 4.08Å; I156-I339 HydrophobicContact CD1-CG2 3.78Å; I156-I339 HydrophobicContact CG1-CG2 4.34Å; I156-I339 HydrophobicContact CG2-CG2 4.4Å; A254-I339 HydrophobicContact CB-CB 3.91Å; A254-I339 HydrophobicContact CB-CG2 3.45Å; A254-I339 VanDerWaalsContact CB-CG2 3.45Å; V257-I339 HydrophobicContact CB-CD1 4.13Å; V257-I339 HydrophobicContact CG1-CD1 4.47Å; V257-I339 HydrophobicContact CG2-CD1 3.74Å; S337-I339 VanDerWaalsContact C-N 3.29Å; S337-I339 PolarHBondContact O-N 2.87Å; I339-S341 VanDerWaalsContact C-N 3.31Å; I339-S341 PolarHBondContact O-N 3.32Å; I339-L342 PolarHBondContact O-N 2.7Å; I339-I343 HydrophobicContact CG2-CD1 3.84Å; I339-I343 WeakPolarHBondContact O-CD1 3.36Å; I339-I343 VanDerWaalsContact O-CG1 3.3Å; I339-I343 WeakPolarHBondContact O-CG1 3.4Å; I339-I343 PolarHBondContact O-N 3.17Å
340	M	93.7	Very high	92.7	Very high	15 Å²	15	33.4 Å²	33.4	7%	0.074	17%	0.171	C	C	.	.	H	α-helix	trans	-62.6	-38.3	176.2	-71.4	-60.4	-171.7	0	0	112.2	L251 A254 V255 I292 S337 I343 A344	L251-M340 HydrophobicContact CD2-CE 4.4Å; L251-M340 HydrophobicContact CD2-SD 4.08Å; A254-M340 HydrophobicContact CB-CE 3.51Å; A254-M340 HydrophobicContact CB-CG 3.9Å; A254-M340 HydrophobicContact CB-SD 3.6Å; V255-M340 HydrophobicContact CG2-CE 3.89Å; I292-M340 HydrophobicContact CG1-CB 4.07Å; S337-M340 PolarHBondContact O-N 3.34Å; S337-M340 WeakPolarHBondContact OG-CG 3.45Å; S337-M340 PolarHBondContact OG-N 3.09Å; M340-I343 PolarHBondContact O-N 2.99Å; M340-A344 VanDerWaalsContact O-CB 3.24Å; M340-A344 WeakPolarHBondContact O-CB 3.29Å; M340-A344 PolarHBondContact O-N 2.87Å
341	S	95.8	Very high	92.2	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60.6	-45	175.4	-176.6	0	0	0	0	111.9	G291 G295 A327 S337 G338 I339 A344 C345	G291-S341 WeakPolarHBondContact O-CA 3.1Å; G291-S341 VanDerWaalsContact O-CB 3.26Å; G291-S341 WeakPolarHBondContact O-CB 3.21Å; G295-S341 WeakPolarHBondContact CA-O 3.38Å; G295-S341 WeakPolarHBondContact CA-OG 3.2Å; G295-S341 PolarHBondContact N-OG 3.21Å; A327-S341 VanDerWaalsContact C-OG 3.27Å; A327-S341 WeakPolarHBondContact O-CB 3.48Å; A327-S341 PolarHBondContact O-OG 2.97Å; S337-S341 PolarHBondContact O-N 3.17Å; G338-S341 WeakPolarHBondContact O-CB 3.31Å; G338-S341 PolarHBondContact O-N 3.03Å; I339-S341 VanDerWaalsContact C-N 3.31Å; I339-S341 PolarHBondContact O-N 3.32Å; S341-A344 PolarHBondContact O-N 3.36Å; S341-C345 WeakPolarHBondContact O-CB 3.26Å; S341-C345 PolarHBondContact O-N 2.88Å
342	L	94.9	Very high	91.8	Very high	2 Å²	2	36.7 Å²	36.7	1%	0.01	19%	0.187	C	C	.	.	H	α-helix	trans	-66.4	-42.8	179.7	-171.5	60.5	0	0	0	112.4	P153 I156 L157 S324 Y328 G338 I339 C345 G346	P153-L342 HydrophobicContact CB-CD2 3.69Å; P153-L342 WeakPolarHBondContact O-CD2 3.29Å; I156-L342 HydrophobicContact CB-CD2 3.88Å; I156-L342 HydrophobicContact CG2-CB 4.2Å; I156-L342 HydrophobicContact CG2-CD2 3.84Å; I156-L342 HydrophobicContact CG2-CG 3.98Å; L157-L342 HydrophobicContact CB-CD1 4.38Å; L157-L342 HydrophobicContact CD1-CD1 4.25Å; S324-L342 VanDerWaalsContact O-CD1 3.24Å; S324-L342 WeakPolarHBondContact O-CD1 3.49Å; Y328-L342 HydrophobicContact CD2-CD2 4.43Å; G338-L342 WeakPolarHBondContact O-CB 3.43Å; G338-L342 PolarHBondContact O-N 2.93Å; I339-L342 PolarHBondContact O-N 2.7Å; L342-C345 PolarHBondContact O-N 2.69Å; L342-G346 PolarHBondContact O-N 3.14Å
343	I	94	Very high	91.5	Very high	10 Å²	10	33.5 Å²	33.5	5%	0.051	17%	0.173	C	C	.	.	H	α-helix	trans	-61.3	-51.4	174.2	-65.9	161.9	0	0	0	110.4	I156 L250 L251 A254 I339 M340 C345 G346 V347	I156-I343 HydrophobicContact CG2-CD1 4.25Å; I156-I343 HydrophobicContact CG2-CG1 3.49Å; I156-I343 VanDerWaalsContact CG2-CG1 3.49Å; L250-I343 HydrophobicContact CD2-CD1 3.64Å; L250-I343 HydrophobicContact CD2-CG1 3.94Å; L250-I343 HydrophobicContact CD2-CG2 3.8Å; L250-I343 HydrophobicContact CG-CD1 4.27Å; L250-I343 WeakPolarHBondContact O-CD1 3.22Å; L251-I343 HydrophobicContact CD2-CD1 4.35Å; A254-I343 HydrophobicContact CB-CD1 4.29Å; I339-I343 HydrophobicContact CG2-CD1 3.84Å; I339-I343 WeakPolarHBondContact O-CD1 3.36Å; I339-I343 VanDerWaalsContact O-CG1 3.3Å; I339-I343 WeakPolarHBondContact O-CG1 3.4Å; I339-I343 PolarHBondContact O-N 3.17Å; M340-I343 PolarHBondContact O-N 2.99Å; I343-C345 VanDerWaalsContact C-N 3.31Å; I343-C345 PolarHBondContact O-N 3.34Å; I343-G346 PolarHBondContact O-N 2.87Å; I343-V347 HydrophobicContact CG2-CG2 4.33Å; I343-V347 WeakPolarHBondContact O-CB 3.41Å; I343-V347 VanDerWaalsContact O-CG2 3.31Å; I343-V347 WeakPolarHBondContact O-CG2 3.41Å; I343-V347 PolarHBondContact O-N 3.48Å
344	A	94.3	Very high	91.1	Very high	13 Å²	13	32.4 Å²	32.4	11%	0.107	16%	0.161	C	C	.	.	H	α-helix	trans	-61.9	-39.9	-179.4	0	0	0	0	0	111.6	I292 M340 S341 V348	I292-A344 HydrophobicContact CB-CB 4.43Å; I292-A344 HydrophobicContact CG2-CB 4.15Å; M340-A344 VanDerWaalsContact O-CB 3.24Å; M340-A344 WeakPolarHBondContact O-CB 3.29Å; M340-A344 PolarHBondContact O-N 2.87Å; S341-A344 PolarHBondContact O-N 3.36Å; A344-V348 VanDerWaalsContact O-CB 3.32Å; A344-V348 WeakPolarHBondContact O-CB 3.27Å; A344-V348 VanDerWaalsContact O-CG2 3.25Å; A344-V348 WeakPolarHBondContact O-CG2 3.47Å; A344-V348 PolarHBondContact O-N 3.44Å
345	C	95.4	Very high	90.6	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-59.6	-54.2	173.8	-174.6	0	0	0	0	111.4	G295 S324 A327 S341 L342 I343 V347 V348 M349	G295-C345 VanDerWaalsContact O-CA 3.23Å; G295-C345 WeakPolarHBondContact O-CA 3.47Å; G295-C345 WeakPolarHBondContact O-CB 3.29Å; S324-C345 PolarHBondContact OG-SG 3.28Å; S324-C345 VanDerWaalsContact OG-SG 3.41Å; A327-C345 HydrophobicContact CB-CB 3.98Å; S341-C345 WeakPolarHBondContact O-CB 3.26Å; S341-C345 PolarHBondContact O-N 2.88Å; L342-C345 PolarHBondContact O-N 2.69Å; I343-C345 VanDerWaalsContact C-N 3.31Å; I343-C345 PolarHBondContact O-N 3.34Å; C345-V347 PolarHBondContact O-N 3.24Å; C345-V348 PolarHBondContact O-N 3.14Å; C345-M349 WeakPolarHBondContact O-CB 3.36Å; C345-M349 PolarHBondContact O-N 3.06Å
346	G	93.1	Very high	90.2	Very high	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-58.9	-44.8	179.9	0	0	0	0	0	113	L342 I343 M349 R350	L342-G346 PolarHBondContact O-N 3.14Å; I343-G346 PolarHBondContact O-N 2.87Å; G346-M349 PolarHBondContact O-N 3.18Å; G346-R350 WeakPolarHBondContact O-CB 3.21Å; G346-R350 PolarHBondContact O-N 3.35Å
347	V	91.6	Very high	89.7	Confident	34 Å²	34	18.6 Å²	18.6	21%	0.206	10%	0.104	C	C	.	.	H	α-helix	trans	-65.3	-42.3	179.7	167.4	0	0	0	0	112.6	L163 I165 I343 C345 P351	L163-V347 HydrophobicContact CD2-CG2 3.6Å; I165-V347 HydrophobicContact CD1-CG1 3.65Å; I343-V347 HydrophobicContact CG2-CG2 4.33Å; I343-V347 WeakPolarHBondContact O-CB 3.41Å; I343-V347 VanDerWaalsContact O-CG2 3.31Å; I343-V347 WeakPolarHBondContact O-CG2 3.41Å; I343-V347 PolarHBondContact O-N 3.48Å; C345-V347 PolarHBondContact O-N 3.24Å; V347-P351 VanDerWaalsContact O-CD 3.22Å; V347-P351 WeakPolarHBondContact O-CD 3.31Å
348	V	91.3	Very high	89.1	Confident	32 Å²	32	19.2 Å²	19.2	19%	0.194	11%	0.108	C	C	.	.	H	α-helix	trans	-71.3	-41.8	176.8	169.9	0	0	0	0	111	V296 V300 A344 C345 P351 Y352	V296-V348 HydrophobicContact CG2-CG2 4.03Å; V300-V348 HydrophobicContact CG2-CG1 4Å; A344-V348 VanDerWaalsContact O-CB 3.32Å; A344-V348 WeakPolarHBondContact O-CB 3.27Å; A344-V348 VanDerWaalsContact O-CG2 3.25Å; A344-V348 WeakPolarHBondContact O-CG2 3.47Å; A344-V348 PolarHBondContact O-N 3.44Å; C345-V348 PolarHBondContact O-N 3.14Å; V348-P351 WeakPolarHBondContact O-CD 3.32Å; V348-Y352 HydrophobicContact CG1-CE2 4.49Å; V348-Y352 WeakPolarHBondContact O-CD2 3.41Å; V348-Y352 VanDerWaalsContact O-CE2 3.31Å; V348-Y352 WeakPolarHBondContact O-CE2 3.24Å
349	M	89.8	Confident	88.7	Confident	2 Å²	2	26.5 Å²	26.5	1%	0.01	14%	0.142	C	C	.	.	H	α-helix	trans	-68.2	-46.1	-174.2	-172.1	169.2	-162.5	0	0	112.2	V320 C345 G346 Y352 V353	V320-M349 HydrophobicContact CB-CE 4.22Å; V320-M349 HydrophobicContact CB-SD 4.47Å; V320-M349 HydrophobicContact CG1-SD 4.14Å; V320-M349 HydrophobicContact CG2-CE 3.97Å; C345-M349 WeakPolarHBondContact O-CB 3.36Å; C345-M349 PolarHBondContact O-N 3.06Å; G346-M349 PolarHBondContact O-N 3.18Å; M349-Y352 PolarHBondContact O-N 3.3Å; M349-V353 HydrophobicContact CE-CG2 3.77Å; M349-V353 HydrophobicContact CG-CB 4.16Å; M349-V353 HydrophobicContact CG-CG2 3.33Å; M349-V353 WeakPolarHBondContact O-CB 3.38Å; M349-V353 WeakPolarHBondContact O-CG2 3.44Å; M349-V353 PolarHBondContact O-N 3.11Å; M349-V353 HydrophobicContact SD-CG2 4.37Å
350	R	88.5	Confident	88.2	Confident	44 Å²	44	34.6 Å²	34.6	17%	0.166	18%	0.176	C	C	.	.	H	α-helix	trans	-46.6	-58.3	-173.9	-174.9	-133.4	179.4	120.1	-3.9	114.8	Y161 F162 L163 G346 Y352 V353 E354	Y161-R350 HydrophobicContact CD1-CG 4.26Å; Y161-R350 HydrophobicContact CD2-CB 4.01Å; Y161-R350 HydrophobicContact CE1-CG 4.13Å; Y161-R350 HydrophobicContact CE2-CB 3.98Å; Y161-R350 HydrophobicContact CE2-CG 4.4Å; Y161-R350 HydrophobicContact CG-CB 4.33Å; Y161-R350 HydrophobicContact CG-CG 4.45Å; Y161-R350 WeakPolarHBondContact O-CD 3.23Å; Y161-R350 VanDerWaalsContact O-CG 3.24Å; Y161-R350 WeakPolarHBondContact O-CG 3.5Å; Y161-R350 PolarHBondContact O-NH1 3.47Å; F162-R350 VanDerWaalsContact CA-NH1 3.32Å; F162-R350 PolarHBondContact O-NH1 3.06Å; L163-R350 PolarHBondContact O-NH1 2.98Å; G346-R350 WeakPolarHBondContact O-CB 3.21Å; G346-R350 PolarHBondContact O-N 3.35Å; R350-Y352 VanDerWaalsContact C-N 3.27Å; R350-Y352 PolarHBondContact O-N 2.78Å; R350-V353 PolarHBondContact O-N 3.5Å; R350-E354 IonicContact CZ-OE2 3.37Å; R350-E354 IonicContact NE-OE2 2.96Å; R350-E354 PolarHBondContact NE-OE2 2.96Å; R350-E354 VanDerWaalsContact NE-OE2 3.07Å; R350-E354 IonicContact NH2-OE2 2.71Å; R350-E354 WeakPolarHBondContact O-CB 3.34Å; R350-E354 PolarHBondContact O-N 3.25Å
351	P	84.4	Confident	87.9	Confident	58 Å²	58	34.2 Å²	34.2	38%	0.377	18%	0.175	S	C	.	.	H	α-helix	trans	-66.3	-21.9	-172.3	26.8	-37.2	0	0	0	115.1	V347 V348	V347-P351 VanDerWaalsContact O-CD 3.22Å; V347-P351 WeakPolarHBondContact O-CD 3.31Å; V348-P351 WeakPolarHBondContact O-CD 3.32Å
352	Y	85.1	Confident	87.5	Confident	33 Å²	33	36.4 Å²	36.4	13%	0.129	18%	0.184	C	C	.	.	H	α-helix	trans	-93.1	-41.8	177.4	-53.2	-65	0	0	0	111.2	A303 V348 M349 R350 A355 N356 N542 V546 L550	A303-Y352 HydrophobicContact CB-CD2 4.09Å; A303-Y352 HydrophobicContact CB-CG 4.25Å; V348-Y352 HydrophobicContact CG1-CE2 4.49Å; V348-Y352 WeakPolarHBondContact O-CD2 3.41Å; V348-Y352 VanDerWaalsContact O-CE2 3.31Å; V348-Y352 WeakPolarHBondContact O-CE2 3.24Å; M349-Y352 PolarHBondContact O-N 3.3Å; R350-Y352 VanDerWaalsContact C-N 3.27Å; R350-Y352 PolarHBondContact O-N 2.78Å; Y352-A355 WeakPolarHBondContact O-CB 3.32Å; Y352-A355 PolarHBondContact O-N 3.41Å; Y352-A355 VanDerWaalsContact O-N 3.16Å; Y352-N356 PolarHBondContact O-N 3.5Å; Y352-N356 VanDerWaalsContact O-N 3.08Å; Y352-N542 PolarHBondContact OH-ND2 3.46Å; Y352-V546 HydrophobicContact CE1-CG1 3.64Å; Y352-V546 HydrophobicContact CE2-CG1 4.36Å; Y352-V546 WeakPolarHBondContact OH-CG1 3.44Å; Y352-L550 HydrophobicContact CD1-CB 4.29Å; Y352-L550 HydrophobicContact CD1-CD1 4.43Å; Y352-L550 HydrophobicContact CD2-CD1 4.46Å; Y352-L550 HydrophobicContact CG-CB 4.39Å; Y352-L550 HydrophobicContact CG-CD1 4.42Å
353	V	85.7	Confident	87.3	Confident	1 Å²	1	38.4 Å²	38.4	1%	0.006	20%	0.196	C	C	.	.	H	α-helix	trans	-65.4	-42.1	177.2	171.4	0	0	0	0	111.1	Y161 A303 V320 M349 R350 A355 N356 I357	Y161-V353 WeakPolarHBondContact OH-CG1 3.39Å; A303-V353 HydrophobicContact CB-CG2 4.4Å; V320-V353 HydrophobicContact CG2-CG1 4.09Å; M349-V353 HydrophobicContact CE-CG2 3.77Å; M349-V353 HydrophobicContact CG-CB 4.16Å; M349-V353 HydrophobicContact CG-CG2 3.33Å; M349-V353 WeakPolarHBondContact O-CB 3.38Å; M349-V353 WeakPolarHBondContact O-CG2 3.44Å; M349-V353 PolarHBondContact O-N 3.11Å; M349-V353 HydrophobicContact SD-CG2 4.37Å; R350-V353 PolarHBondContact O-N 3.5Å; V353-A355 PolarHBondContact O-N 3.06Å; V353-N356 PolarHBondContact O-N 3.36Å; V353-N356 VanDerWaalsContact O-N 3.08Å; V353-I357 HydrophobicContact CG1-CD1 3.31Å; V353-I357 HydrophobicContact CG1-CG1 3.8Å; V353-I357 VanDerWaalsContact O-CB 3.28Å; V353-I357 WeakPolarHBondContact O-CB 3.15Å; V353-I357 PolarHBondContact O-N 2.98Å
354	E	83.4	Confident	87.1	Confident	87 Å²	87	41.6 Å²	41.6	41%	0.407	22%	0.217	S	C	.	.	H	α-helix	trans	-60	-25.8	174.2	-171.5	173.2	153.5	0	0	112.7	R350 Y362	R350-E354 IonicContact CZ-OE2 3.37Å; R350-E354 IonicContact NE-OE2 2.96Å; R350-E354 PolarHBondContact NE-OE2 2.96Å; R350-E354 VanDerWaalsContact NE-OE2 3.07Å; R350-E354 IonicContact NH2-OE2 2.71Å; R350-E354 WeakPolarHBondContact O-CB 3.34Å; R350-E354 PolarHBondContact O-N 3.25Å; E354-Y362 HydrophobicContact CB-CD2 4.37Å; E354-Y362 HydrophobicContact CB-CE2 4.13Å; E354-Y362 HydrophobicContact CG-CD2 3.93Å; E354-Y362 HydrophobicContact CG-CE2 3.55Å; E354-Y362 PolarHBondContact OE2-OH 3.3Å
355	A	80.4	Confident	86.9	Confident	36 Å²	36	41 Å²	41	30%	0.298	21%	0.211	S	C	.	.	H	α-helix	trans	-84.1	-29.7	174.5	0	0	0	0	0	113.8	Y352 V353 I551	Y352-A355 WeakPolarHBondContact O-CB 3.32Å; Y352-A355 PolarHBondContact O-N 3.41Å; Y352-A355 VanDerWaalsContact O-N 3.16Å; V353-A355 PolarHBondContact O-N 3.06Å; A355-I551 HydrophobicContact CB-CD1 4.13Å; A355-I551 HydrophobicContact CB-CG1 4.41Å
356	N	81.1	Confident	86.7	Confident	2 Å²	2	45.9 Å²	45.9	1%	0.011	23%	0.233	C	C	.	.	H	α-helix	trans	-87.9	-35.2	-178.7	-75.6	-24.1	0	0	0	113.6	S306 Y352 V353 L550 I551 A552 R555	S306-N356 PolarHBondContact OG-ND2 3.4Å; Y352-N356 PolarHBondContact O-N 3.5Å; Y352-N356 VanDerWaalsContact O-N 3.08Å; V353-N356 PolarHBondContact O-N 3.36Å; V353-N356 VanDerWaalsContact O-N 3.08Å; N356-L550 PolarHBondContact ND2-O 3.37Å; N356-I551 VanDerWaalsContact OD1-CA 3.29Å; N356-I551 WeakPolarHBondContact OD1-CA 3.48Å; N356-A552 PolarHBondContact OD1-N 2.92Å; N356-R555 PolarHBondContact O-NH1 2.96Å
357	I	81.4	Confident	86.6	Confident	10 Å²	10	53.6 Å²	53.6	5%	0.051	26%	0.263	C	S	.	.	S	Bend	trans	-76.7	153.1	-173.4	-81.1	-168.5	0	0	0	112.8	E316 V320 V353 S361 Y362 I365 R555	E316-I357 HydrophobicContact CB-CD1 3.82Å; E316-I357 HydrophobicContact CB-CG1 4.09Å; E316-I357 HydrophobicContact CG-CG1 4.23Å; E316-I357 WeakPolarHBondContact OE2-CG2 3.24Å; V320-I357 HydrophobicContact CG2-CD1 4.49Å; V353-I357 HydrophobicContact CG1-CD1 3.31Å; V353-I357 HydrophobicContact CG1-CG1 3.8Å; V353-I357 VanDerWaalsContact O-CB 3.28Å; V353-I357 WeakPolarHBondContact O-CB 3.15Å; V353-I357 PolarHBondContact O-N 2.98Å; I357-S361 WeakPolarHBondContact CG2-OG 3.41Å; I357-Y362 VanDerWaalsContact CG2-N 3.32Å; I357-I365 HydrophobicContact CD1-CD1 3.4Å; I357-I365 HydrophobicContact CG2-CD1 4.46Å; I357-R555 PolarHBondContact O-NH1 2.97Å
358	S	81.8	Confident	86.6	Confident	21 Å²	21	55.7 Å²	55.7	15%	0.147	27%	0.269	C	S	.	.			trans	-75.3	142.7	171.4	-171.8	0	0	0	0	111.8	E316 K360 S361 Y362	E316-S358 PolarHBondContact OE2-N 3.3Å; S358-K360 PolarHBondContact O-N 3.32Å; S358-S361 WeakPolarHBondContact O-CA 3.46Å; S358-S361 PolarHBondContact O-N 2.78Å; S358-Y362 PolarHBondContact O-N 3.41Å
359	H	83.4	Confident	86.7	Confident	154 Å²	154	54.3 Å²	54.3	71%	0.713	26%	0.261	S	S	*	.	H	α-helix	trans	-50.4	-34.2	179.1	-169.4	-65.4	0	0	0	113.8	T363	H359-T363 PolarHBondContact ND1-OG1 2.92Å; H359-T363 WeakPolarHBondContact O-CB 3.43Å; H359-T363 PolarHBondContact O-N 3.41Å; H359-T363 PolarHBondContact O-OG1 3.46Å
360	K	84.2	Confident	86.7	Confident	172 Å²	172	59.9 Å²	59.9	75%	0.748	29%	0.285	S	S	*	.	H	α-helix	trans	-62.2	-48.1	174.7	-68.7	-169.1	177.3	-171.7	0	111.8	S358 T363 T364	S358-K360 PolarHBondContact O-N 3.32Å; K360-T363 WeakPolarHBondContact O-CB 3.46Å; K360-T363 PolarHBondContact O-N 3.43Å; K360-T364 PolarHBondContact O-N 3.21Å; K360-T364 PolarHBondContact O-OG1 3.28Å
361	S	86.5	Confident	86.8	Confident	7 Å²	7	62.7 Å²	62.7	5%	0.049	30%	0.301	C	S	.	.	H	α-helix	trans	-70.8	-37.4	-179.9	162	0	0	0	0	112.4	E316 I357 S358 T363 T364 I365	E316-S361 VanDerWaalsContact CB-OG 3.29Å; E316-S361 WeakPolarHBondContact CB-OG 3.34Å; E316-S361 WeakPolarHBondContact OE2-CB 3.4Å; E316-S361 PolarHBondContact OE2-OG 2.94Å; I357-S361 WeakPolarHBondContact CG2-OG 3.41Å; S358-S361 WeakPolarHBondContact O-CA 3.46Å; S358-S361 PolarHBondContact O-N 2.78Å; S361-T363 VanDerWaalsContact C-N 3.26Å; S361-T363 PolarHBondContact O-N 2.96Å; S361-T364 WeakPolarHBondContact O-CB 3.15Å; S361-T364 PolarHBondContact O-N 3.24Å; S361-T364 VanDerWaalsContact O-N 3.11Å; S361-I365 WeakPolarHBondContact O-CG1 3.48Å; S361-I365 PolarHBondContact O-N 3.46Å
362	Y	87.7	Confident	87.1	Confident	46 Å²	46	65 Å²	65	18%	0.18	30%	0.303	C	S	.	.	H	α-helix	trans	-57.4	-41	169	-179.9	-94	0	0	0	112	E354 I357 S358 I365 K366	E354-Y362 HydrophobicContact CB-CD2 4.37Å; E354-Y362 HydrophobicContact CB-CE2 4.13Å; E354-Y362 HydrophobicContact CG-CD2 3.93Å; E354-Y362 HydrophobicContact CG-CE2 3.55Å; E354-Y362 PolarHBondContact OE2-OH 3.3Å; I357-Y362 VanDerWaalsContact CG2-N 3.32Å; S358-Y362 PolarHBondContact O-N 3.41Å; Y362-I365 PolarHBondContact O-N 3.45Å; Y362-K366 WeakPolarHBondContact O-CB 3.26Å; Y362-K366 PolarHBondContact O-N 3.41Å
363	T	89.6	Confident	87.4	Confident	45 Å²	45	63.8 Å²	63.8	28%	0.276	30%	0.299	S	S	.	.	H	α-helix	trans	-65.8	-40.7	176.4	-54.7	0	0	0	0	111.1	H359 K360 S361 K366 Y367	H359-T363 PolarHBondContact ND1-OG1 2.92Å; H359-T363 WeakPolarHBondContact O-CB 3.43Å; H359-T363 PolarHBondContact O-N 3.41Å; H359-T363 PolarHBondContact O-OG1 3.46Å; K360-T363 WeakPolarHBondContact O-CB 3.46Å; K360-T363 PolarHBondContact O-N 3.43Å; S361-T363 VanDerWaalsContact C-N 3.26Å; S361-T363 PolarHBondContact O-N 2.96Å; T363-K366 PolarHBondContact O-N 3.36Å; T363-Y367 HydrophobicContact CG2-CD2 3.67Å; T363-Y367 HydrophobicContact CG2-CE2 3.45Å; T363-Y367 VanDerWaalsContact CG2-CE2 3.45Å; T363-Y367 VanDerWaalsContact O-CD2 3.29Å; T363-Y367 WeakPolarHBondContact O-CD2 3.46Å; T363-Y367 PolarHBondContact O-N 2.83Å
364	T	90.3	Very high	87.4	Confident	77 Å²	77	65.3 Å²	65.3	47%	0.472	31%	0.309	S	S	.	.	H	α-helix	trans	-60.4	-49.7	172.4	-54.1	0	0	0	0	112	P317 K360 S361 K366 Y367 F368	P317-T364 HydrophobicContact CG-CG2 4.23Å; K360-T364 PolarHBondContact O-N 3.21Å; K360-T364 PolarHBondContact O-OG1 3.28Å; S361-T364 WeakPolarHBondContact O-CB 3.15Å; S361-T364 PolarHBondContact O-N 3.24Å; S361-T364 VanDerWaalsContact O-N 3.11Å; T364-K366 VanDerWaalsContact C-N 3.3Å; T364-K366 PolarHBondContact O-N 2.8Å; T364-Y367 PolarHBondContact O-N 3.39Å; T364-F368 WeakPolarHBondContact O-CB 3.4Å; T364-F368 PolarHBondContact O-N 2.88Å
365	I	90.8	Very high	87.6	Confident	0 Å²	0	63.5 Å²	63.5	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-55.3	-47.2	177.2	-69.4	158	0	0	0	110.2	Y161 P317 V320 I357 S361 Y362 L369	Y161-I365 HydrophobicContact CE1-CG2 4.03Å; P317-I365 HydrophobicContact CB-CD1 4.36Å; P317-I365 HydrophobicContact CB-CG1 3.59Å; P317-I365 HydrophobicContact CG-CD1 4.47Å; P317-I365 HydrophobicContact CG-CG1 3.95Å; V320-I365 HydrophobicContact CG2-CD1 3.83Å; V320-I365 HydrophobicContact CG2-CG1 4.38Å; I357-I365 HydrophobicContact CD1-CD1 3.4Å; I357-I365 HydrophobicContact CG2-CD1 4.46Å; S361-I365 WeakPolarHBondContact O-CG1 3.48Å; S361-I365 PolarHBondContact O-N 3.46Å; Y362-I365 PolarHBondContact O-N 3.45Å; I365-L369 HydrophobicContact CG2-CD1 3.82Å; I365-L369 HydrophobicContact CG2-CG 4.49Å; I365-L369 VanDerWaalsContact O-CB 3.3Å; I365-L369 WeakPolarHBondContact O-CB 3.34Å; I365-L369 PolarHBondContact O-N 3.44Å
366	K	90.8	Very high	88	Confident	102 Å²	102	61.9 Å²	61.9	44%	0.443	29%	0.291	S	S	.	.	H	α-helix	trans	-60.8	-52.7	180	-175.5	179.4	179.2	-176.2	0	112.9	F162 Y362 T363 T364 K370	F162-K366 HydrophobicContact CE1-CB 4.15Å; F162-K366 HydrophobicContact CE1-CD 4.45Å; F162-K366 HydrophobicContact CE1-CG 4.03Å; F162-K366 HydrophobicContact CE2-CB 4.37Å; F162-K366 HydrophobicContact CE2-CG 4.21Å; F162-K366 VanDerWaalsContact CZ-CA 3.48Å; F162-K366 HydrophobicContact CZ-CB 3.63Å; F162-K366 HydrophobicContact CZ-CG 3.73Å; Y362-K366 WeakPolarHBondContact O-CB 3.26Å; Y362-K366 PolarHBondContact O-N 3.41Å; T363-K366 PolarHBondContact O-N 3.36Å; T364-K366 VanDerWaalsContact C-N 3.3Å; T364-K366 PolarHBondContact O-N 2.8Å; K366-K370 VanDerWaalsContact O-CB 3.32Å; K366-K370 WeakPolarHBondContact O-CB 3.34Å; K366-K370 PolarHBondContact O-N 2.92Å
367	Y	91.9	Very high	88.2	Confident	163 Å²	163	63.3 Å²	63.3	64%	0.639	30%	0.297	S	S	*	.	H	α-helix	trans	-69.9	-34	-178.5	-72.6	-58.5	0	0	0	112.6	T363 T364 M371	T363-Y367 HydrophobicContact CG2-CD2 3.67Å; T363-Y367 HydrophobicContact CG2-CE2 3.45Å; T363-Y367 VanDerWaalsContact CG2-CE2 3.45Å; T363-Y367 VanDerWaalsContact O-CD2 3.29Å; T363-Y367 WeakPolarHBondContact O-CD2 3.46Å; T363-Y367 PolarHBondContact O-N 2.83Å; T364-Y367 PolarHBondContact O-N 3.39Å; Y367-M371 WeakPolarHBondContact O-CB 3.38Å; Y367-M371 PolarHBondContact O-N 3.38Å
368	F	91.6	Very high	88.4	Confident	77 Å²	77	63 Å²	63	34%	0.338	30%	0.296	S	S	.	.	H	α-helix	trans	-71.5	-43.9	178.3	-176.2	-90.7	0	0	0	112.3	F321 T364 M371 W372	F321-F368 HydrophobicContact CD1-CD1 4.42Å; F321-F368 HydrophobicContact CD1-CE1 4.19Å; F321-F368 HydrophobicContact CD2-CD1 4.3Å; F321-F368 AromaticContact CD2-CE1 4Å; F321-F368 HydrophobicContact CD2-CE1 4Å; F321-F368 AromaticContact CE1-CD1 3.65Å; F321-F368 HydrophobicContact CE1-CD1 3.65Å; F321-F368 AromaticContact CE1-CE1 3.86Å; F321-F368 HydrophobicContact CE1-CE1 3.86Å; F321-F368 AromaticContact CE2-CD1 3.54Å; F321-F368 HydrophobicContact CE2-CD1 3.54Å; F321-F368 AromaticContact CE2-CE1 3.69Å; F321-F368 HydrophobicContact CE2-CE1 3.69Å; F321-F368 HydrophobicContact CE2-CG 4.49Å; F321-F368 HydrophobicContact CG-CE1 4.29Å; F321-F368 HydrophobicContact CZ-CB 4.5Å; F321-F368 AromaticContact CZ-CD1 3.21Å; F321-F368 HydrophobicContact CZ-CD1 3.21Å; F321-F368 AromaticContact CZ-CE1 3.68Å; F321-F368 HydrophobicContact CZ-CE1 3.68Å; F321-F368 HydrophobicContact CZ-CG 4.24Å; T364-F368 WeakPolarHBondContact O-CB 3.4Å; T364-F368 PolarHBondContact O-N 2.88Å; F368-M371 HydrophobicContact CD2-CE 3.82Å; F368-M371 HydrophobicContact CE2-CE 4.13Å; F368-M371 PolarHBondContact O-N 3.19Å; F368-W372 HydrophobicContact CD1-CE3 4.22Å; F368-W372 AromaticContact CE1-CE3 3.34Å; F368-W372 HydrophobicContact CE1-CE3 3.34Å; F368-W372 AromaticContact CE1-CZ3 3.61Å; F368-W372 HydrophobicContact CE1-CZ3 3.61Å; F368-W372 AromaticContact CZ-CE3 3.63Å; F368-W372 HydrophobicContact CZ-CE3 3.63Å; F368-W372 AromaticContact CZ-CZ3 3.76Å; F368-W372 HydrophobicContact CZ-CZ3 3.76Å; F368-W372 WeakPolarHBondContact O-CB 3.18Å; F368-W372 PolarHBondContact O-N 3.5Å
369	L	91.6	Very high	88.6	Confident	3 Å²	3	63.4 Å²	63.4	2%	0.016	30%	0.296	C	S	.	.	H	α-helix	trans	-57.3	-49.6	171.2	-87.2	171	0	0	0	111.2	L157 D158 Y161 F162 F321 I365 M371 W372 S373	L157-L369 HydrophobicContact CB-CD2 4.11Å; L157-L369 HydrophobicContact CD2-CD2 3.89Å; L157-L369 HydrophobicContact CG-CD2 3.71Å; D158-L369 HydrophobicContact CB-CB 4.33Å; D158-L369 HydrophobicContact CB-CD2 4.49Å; Y161-L369 HydrophobicContact CD1-CD1 4.08Å; Y161-L369 HydrophobicContact CG-CD1 4.2Å; F162-L369 HydrophobicContact CD2-CD1 4.38Å; F162-L369 HydrophobicContact CE2-CB 4.03Å; F162-L369 HydrophobicContact CE2-CD1 3.57Å; F162-L369 HydrophobicContact CE2-CG 4.44Å; F162-L369 HydrophobicContact CZ-CD1 4.21Å; F321-L369 HydrophobicContact CD1-CD2 4.34Å; F321-L369 HydrophobicContact CE1-CD2 3.56Å; F321-L369 HydrophobicContact CE1-CG 3.64Å; F321-L369 HydrophobicContact CZ-CD2 4.47Å; F321-L369 HydrophobicContact CZ-CG 4.07Å; I365-L369 HydrophobicContact CG2-CD1 3.82Å; I365-L369 HydrophobicContact CG2-CG 4.49Å; I365-L369 VanDerWaalsContact O-CB 3.3Å; I365-L369 WeakPolarHBondContact O-CB 3.34Å; I365-L369 PolarHBondContact O-N 3.44Å; L369-M371 VanDerWaalsContact C-N 3.32Å; L369-M371 PolarHBondContact O-N 2.83Å; L369-W372 PolarHBondContact O-N 2.9Å; L369-S373 WeakPolarHBondContact O-CB 3.4Å; L369-S373 PolarHBondContact O-N 3.25Å
370	K	90.3	Very high	88.8	Confident	119 Å²	119	56.5 Å²	56.5	52%	0.517	26%	0.264	S	S	.	.	H	α-helix	trans	-65.1	-37.3	-177.4	-162.3	69.8	-165	160.4	0	112.5	D158 K366 S374	D158-K370 WeakPolarHBondContact OD2-CD 3.31Å; D158-K370 IonicContact OD2-NZ 3.76Å; D158-K370 PolarHBondContact OD2-NZ 3.07Å; K366-K370 VanDerWaalsContact O-CB 3.32Å; K366-K370 WeakPolarHBondContact O-CB 3.34Å; K366-K370 PolarHBondContact O-N 2.92Å; K370-S374 VanDerWaalsContact O-CB 3.29Å; K370-S374 WeakPolarHBondContact O-CB 3.4Å; K370-S374 PolarHBondContact O-N 2.92Å; K370-S374 VanDerWaalsContact O-N 3.1Å
371	M	90.9	Very high	88.8	Confident	103 Å²	103	48.5 Å²	48.5	51%	0.507	23%	0.23	S	C	.	.	H	α-helix	trans	-66.5	-50.1	174.8	178.9	-86.9	-67.4	0	0	111.5	Y367 F368 L369 S374 V375	Y367-M371 WeakPolarHBondContact O-CB 3.38Å; Y367-M371 PolarHBondContact O-N 3.38Å; F368-M371 HydrophobicContact CD2-CE 3.82Å; F368-M371 HydrophobicContact CE2-CE 4.13Å; F368-M371 PolarHBondContact O-N 3.19Å; L369-M371 VanDerWaalsContact C-N 3.32Å; L369-M371 PolarHBondContact O-N 2.83Å; M371-S374 PolarHBondContact O-N 3.26Å; M371-V375 WeakPolarHBondContact O-CG2 3.48Å; M371-V375 PolarHBondContact O-N 2.93Å; M371-V375 HydrophobicContact SD-CG2 4.28Å
372	W	91.4	Very high	88.7	Confident	108 Å²	108	48.8 Å²	48.8	41%	0.409	23%	0.23	S	C	.	.	H	α-helix	trans	-64.3	-48.7	-179.7	-163.3	-20.4	0	0	0	111.4	P154 F368 L369 S374 V375 S376	P154-W372 HydrophobicContact CB-CB 4.29Å; P154-W372 HydrophobicContact CB-CD2 4.19Å; P154-W372 HydrophobicContact CB-CG 3.75Å; P154-W372 VanDerWaalsContact CG-CD1 3.49Å; P154-W372 HydrophobicContact CG-CD2 4.05Å; P154-W372 HydrophobicContact CG-CG 3.99Å; P154-W372 HydrophobicContact CG-CZ2 4.29Å; P154-W372 VanDerWaalsContact CG-NE1 3.26Å; F368-W372 HydrophobicContact CD1-CE3 4.22Å; F368-W372 AromaticContact CE1-CE3 3.34Å; F368-W372 HydrophobicContact CE1-CE3 3.34Å; F368-W372 AromaticContact CE1-CZ3 3.61Å; F368-W372 HydrophobicContact CE1-CZ3 3.61Å; F368-W372 AromaticContact CZ-CE3 3.63Å; F368-W372 HydrophobicContact CZ-CE3 3.63Å; F368-W372 AromaticContact CZ-CZ3 3.76Å; F368-W372 HydrophobicContact CZ-CZ3 3.76Å; F368-W372 WeakPolarHBondContact O-CB 3.18Å; F368-W372 PolarHBondContact O-N 3.5Å; L369-W372 PolarHBondContact O-N 2.9Å; W372-S374 VanDerWaalsContact C-N 3.31Å; W372-S374 PolarHBondContact O-N 3.32Å; W372-V375 PolarHBondContact O-N 3.18Å; W372-V375 VanDerWaalsContact O-N 3.09Å; W372-S376 PolarHBondContact O-N 2.99Å; W372-S376 PolarHBondContact O-OG 3.45Å
373	S	90.7	Very high	88.5	Confident	6 Å²	6	48.6 Å²	48.6	4%	0.042	23%	0.231	C	C	.	.	H	α-helix	trans	-51.3	-49.4	174.6	175.7	0	0	0	0	111.5	D158 L369 V375 S376 E377	D158-S373 PolarHBondContact OD2-OG 3.09Å; L369-S373 WeakPolarHBondContact O-CB 3.4Å; L369-S373 PolarHBondContact O-N 3.25Å; S373-V375 PolarHBondContact O-N 3.47Å; S373-S376 PolarHBondContact O-N 3.16Å; S373-E377 WeakPolarHBondContact O-CB 3.26Å; S373-E377 PolarHBondContact O-N 2.84Å
374	S	86.1	Confident	88.3	Confident	33 Å²	33	46.4 Å²	46.4	23%	0.231	22%	0.217	C	C	.	.	H	α-helix	trans	-69.1	-31	179.3	-160.8	0	0	0	0	113.7	K102 K370 M371 W372 T378	K102-S374 PolarHBondContact NZ-OG 3.46Å; K370-S374 VanDerWaalsContact O-CB 3.29Å; K370-S374 WeakPolarHBondContact O-CB 3.4Å; K370-S374 PolarHBondContact O-N 2.92Å; K370-S374 VanDerWaalsContact O-N 3.1Å; M371-S374 PolarHBondContact O-N 3.26Å; W372-S374 VanDerWaalsContact C-N 3.31Å; W372-S374 PolarHBondContact O-N 3.32Å; S374-T378 VanDerWaalsContact O-CB 3.26Å; S374-T378 WeakPolarHBondContact O-CB 3.43Å; S374-T378 PolarHBondContact O-N 3.27Å; S374-T378 PolarHBondContact O-OG1 2.94Å
375	V	87.3	Confident	88.2	Confident	49 Å²	49	42.8 Å²	42.8	30%	0.297	20%	0.195	S	C	.	.	H	α-helix	trans	-67	-48.1	171.6	169.2	0	0	0	0	110.5	M371 W372 S373 E377 T378 L379	M371-V375 WeakPolarHBondContact O-CG2 3.48Å; M371-V375 PolarHBondContact O-N 2.93Å; M371-V375 HydrophobicContact SD-CG2 4.28Å; W372-V375 PolarHBondContact O-N 3.18Å; W372-V375 VanDerWaalsContact O-N 3.09Å; S373-V375 PolarHBondContact O-N 3.47Å; V375-E377 PolarHBondContact O-N 3.47Å; V375-T378 WeakPolarHBondContact O-CB 3.38Å; V375-T378 PolarHBondContact O-N 2.95Å; V375-L379 HydrophobicContact CG1-CD1 4.14Å; V375-L379 HydrophobicContact CG1-CG 4.48Å; V375-L379 WeakPolarHBondContact O-CG 3.5Å; V375-L379 PolarHBondContact O-N 3.13Å
376	S	88.8	Confident	87.8	Confident	2 Å²	2	43.1 Å²	43.1	1%	0.014	20%	0.197	C	C	.	.	H	α-helix	trans	-57.3	-48.8	176	-72.3	0	0	0	0	111.9	L151 W372 S373 T378 L379 I380	L151-S376 WeakPolarHBondContact O-CB 3.22Å; L151-S376 PolarHBondContact O-OG 3.41Å; W372-S376 PolarHBondContact O-N 2.99Å; W372-S376 PolarHBondContact O-OG 3.45Å; S373-S376 PolarHBondContact O-N 3.16Å; S376-T378 VanDerWaalsContact C-N 3.31Å; S376-T378 PolarHBondContact O-N 2.89Å; S376-L379 PolarHBondContact O-N 3.37Å; S376-I380 WeakPolarHBondContact O-CB 3.36Å; S376-I380 WeakPolarHBondContact O-CG1 3.31Å; S376-I380 PolarHBondContact O-N 2.92Å
377	E	85.7	Confident	87.3	Confident	32 Å²	32	38.3 Å²	38.3	15%	0.15	18%	0.176	C	C	.	.	H	α-helix	trans	-57.1	-44.2	176.1	-173.9	-167	162.9	0	0	111.7	I155 V226 S373 V375 L379 I380 F381	I155-E377 HydrophobicContact CD1-CB 4.41Å; V226-E377 WeakPolarHBondContact CG1-OE1 3.34Å; S373-E377 WeakPolarHBondContact O-CB 3.26Å; S373-E377 PolarHBondContact O-N 2.84Å; V375-E377 PolarHBondContact O-N 3.47Å; E377-L379 PolarHBondContact O-N 2.98Å; E377-I380 PolarHBondContact O-N 3.49Å; E377-F381 HydrophobicContact CG-CD2 3.95Å; E377-F381 HydrophobicContact CG-CE2 3.57Å; E377-F381 WeakPolarHBondContact O-CD2 3.44Å; E377-F381 PolarHBondContact O-N 2.91Å; E377-F381 VanDerWaalsContact O-N 3.14Å
378	T	85.6	Confident	86.9	Confident	5 Å²	5	31.7 Å²	31.7	3%	0.031	15%	0.153	C	C	.	.	H	α-helix	trans	-60.8	-46.8	177.8	-60.2	0	0	0	0	111.4	K102 L121 S374 V375 S376 I382	K102-T378 PolarHBondContact NZ-OG1 3.34Å; L121-T378 HydrophobicContact CD2-CG2 3.94Å; S374-T378 VanDerWaalsContact O-CB 3.26Å; S374-T378 WeakPolarHBondContact O-CB 3.43Å; S374-T378 PolarHBondContact O-N 3.27Å; S374-T378 PolarHBondContact O-OG1 2.94Å; V375-T378 WeakPolarHBondContact O-CB 3.38Å; V375-T378 PolarHBondContact O-N 2.95Å; S376-T378 VanDerWaalsContact C-N 3.31Å; S376-T378 PolarHBondContact O-N 2.89Å; T378-I382 HydrophobicContact CG2-CD1 3.88Å; T378-I382 WeakPolarHBondContact O-CD1 3.5Å; T378-I382 WeakPolarHBondContact O-CG1 3.39Å; T378-I382 PolarHBondContact O-N 3.25Å
379	L	85.4	Confident	86.4	Confident	28 Å²	28	29.4 Å²	29.4	15%	0.147	15%	0.145	C	C	.	.	H	α-helix	trans	-60.6	-46.7	177	-68.7	172.8	0	0	0	111.9	I95 L151 V375 S376 E377 F381 I382 F383	I95-L379 HydrophobicContact CD1-CD2 3.65Å; I95-L379 HydrophobicContact CG1-CD2 3.56Å; I95-L379 HydrophobicContact CG2-CD2 4.48Å; L151-L379 HydrophobicContact CD2-CB 4.23Å; L151-L379 HydrophobicContact CD2-CD1 3.69Å; V375-L379 HydrophobicContact CG1-CD1 4.14Å; V375-L379 HydrophobicContact CG1-CG 4.48Å; V375-L379 WeakPolarHBondContact O-CG 3.5Å; V375-L379 PolarHBondContact O-N 3.13Å; S376-L379 PolarHBondContact O-N 3.37Å; E377-L379 PolarHBondContact O-N 2.98Å; L379-F381 PolarHBondContact O-N 3.45Å; L379-I382 PolarHBondContact O-N 3.38Å; L379-F383 HydrophobicContact CB-CD2 4.29Å; L379-F383 HydrophobicContact CB-CE2 4.09Å; L379-F383 WeakPolarHBondContact O-CD2 3.22Å; L379-F383 PolarHBondContact O-N 2.84Å
380	I	87.1	Confident	85.5	Confident	9 Å²	9	32.1 Å²	32.1	5%	0.046	16%	0.158	C	C	.	.	H	α-helix	trans	-57.9	-47.7	-178.7	-72.9	168.6	0	0	0	111.4	F147 L151 I155 S376 E377 I382 F383 L384 A446	F147-I380 HydrophobicContact CD2-CD1 4.21Å; F147-I380 HydrophobicContact CD2-CG1 4.01Å; F147-I380 HydrophobicContact CE2-CD1 3.69Å; F147-I380 HydrophobicContact CE2-CG1 3.79Å; F147-I380 HydrophobicContact CE2-CG2 3.96Å; F147-I380 HydrophobicContact CZ-CD1 4.43Å; L151-I380 HydrophobicContact CB-CD1 3.97Å; L151-I380 HydrophobicContact CB-CG1 4.03Å; L151-I380 HydrophobicContact CD1-CG1 3.88Å; I155-I380 HydrophobicContact CD1-CD1 3.52Å; S376-I380 WeakPolarHBondContact O-CB 3.36Å; S376-I380 WeakPolarHBondContact O-CG1 3.31Å; S376-I380 PolarHBondContact O-N 2.92Å; E377-I380 PolarHBondContact O-N 3.49Å; I380-I382 PolarHBondContact O-N 2.75Å; I380-F383 PolarHBondContact O-N 2.83Å; I380-L384 WeakPolarHBondContact O-CB 3.43Å; I380-L384 PolarHBondContact O-N 3.29Å; I380-A446 HydrophobicContact CG2-CB 3.08Å
381	F	85.8	Confident	84.4	Confident	5 Å²	5	27 Å²	27	2%	0.022	14%	0.139	C	C	.	.	H	α-helix	trans	-69.1	-31.2	179.5	-72.2	-51.6	0	0	0	113.4	L121 I122 E377 L379 L384 G385 A446	L121-F381 HydrophobicContact CB-CB 3.67Å; L121-F381 HydrophobicContact CB-CG 4.49Å; L121-F381 HydrophobicContact CD1-CB 4.42Å; L121-F381 HydrophobicContact CD1-CD2 4.09Å; I122-F381 HydrophobicContact CD1-CD1 4.05Å; I122-F381 HydrophobicContact CG1-CB 4.1Å; I122-F381 HydrophobicContact CG1-CD1 4.01Å; I122-F381 HydrophobicContact CG1-CG 4.4Å; E377-F381 HydrophobicContact CG-CD2 3.95Å; E377-F381 HydrophobicContact CG-CE2 3.57Å; E377-F381 WeakPolarHBondContact O-CD2 3.44Å; E377-F381 PolarHBondContact O-N 2.91Å; E377-F381 VanDerWaalsContact O-N 3.14Å; L379-F381 PolarHBondContact O-N 3.45Å; F381-L384 HydrophobicContact CD1-CD2 4.22Å; F381-G385 PolarHBondContact O-N 2.88Å; F381-A446 HydrophobicContact CE1-CB 4.49Å
382	I	84.1	Confident	83.2	Confident	12 Å²	12	27.1 Å²	27.1	6%	0.062	15%	0.147	C	C	.	.	H	α-helix	trans	-66.8	-48.5	172.3	-64	157.3	0	0	0	110.2	A98 I128 T378 L379 I380 L384 G385 V386	A98-I382 HydrophobicContact CB-CD1 3.25Å; A98-I382 HydrophobicContact CB-CG1 4.07Å; I128-I382 HydrophobicContact CD1-CG2 4.23Å; T378-I382 HydrophobicContact CG2-CD1 3.88Å; T378-I382 WeakPolarHBondContact O-CD1 3.5Å; T378-I382 WeakPolarHBondContact O-CG1 3.39Å; T378-I382 PolarHBondContact O-N 3.25Å; L379-I382 PolarHBondContact O-N 3.38Å; I380-I382 PolarHBondContact O-N 2.75Å; I382-L384 VanDerWaalsContact C-N 3.31Å; I382-L384 PolarHBondContact O-N 3.23Å; I382-G385 WeakPolarHBondContact O-CA 3.29Å; I382-G385 PolarHBondContact O-N 2.98Å; I382-V386 HydrophobicContact CG2-CG2 4.25Å; I382-V386 WeakPolarHBondContact O-CG2 3.48Å; I382-V386 PolarHBondContact O-N 3.24Å
383	F	83.3	Confident	82.2	Confident	42 Å²	42	25 Å²	25	18%	0.184	14%	0.142	C	C	.	.	H	α-helix	trans	-62.9	-35.9	179.6	-73.6	-53.4	0	0	0	112.7	M142 L151 L379 I380 S387	M142-F383 HydrophobicContact CB-CB 4.13Å; M142-F383 HydrophobicContact CB-CD1 4.39Å; M142-F383 HydrophobicContact CB-CG 4.13Å; M142-F383 HydrophobicContact CG-CD2 4.32Å; M142-F383 HydrophobicContact CG-CG 4.41Å; M142-F383 HydrophobicContact SD-CB 4.07Å; M142-F383 HydrophobicContact SD-CD2 4.12Å; M142-F383 HydrophobicContact SD-CG 4.34Å; L151-F383 HydrophobicContact CD1-CD2 4.42Å; L151-F383 HydrophobicContact CD1-CE2 4.45Å; L379-F383 HydrophobicContact CB-CD2 4.29Å; L379-F383 HydrophobicContact CB-CE2 4.09Å; L379-F383 WeakPolarHBondContact O-CD2 3.22Å; L379-F383 PolarHBondContact O-N 2.84Å; I380-F383 PolarHBondContact O-N 2.83Å; F383-S387 WeakPolarHBondContact O-CB 3.37Å; F383-S387 PolarHBondContact O-N 3Å; F383-S387 PolarHBondContact O-OG 3.43Å
384	L	85.6	Confident	81.4	Confident	0 Å²	0	28 Å²	28	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-58	-46.9	169.5	170.1	63.4	0	0	0	111.4	I122 I380 F381 I382 T388 F449 I476	I122-L384 HydrophobicContact CD1-CD2 3.68Å; I122-L384 HydrophobicContact CG1-CD2 3.92Å; I122-L384 HydrophobicContact CG1-CG 4.48Å; I380-L384 WeakPolarHBondContact O-CB 3.43Å; I380-L384 PolarHBondContact O-N 3.29Å; F381-L384 HydrophobicContact CD1-CD2 4.22Å; I382-L384 VanDerWaalsContact C-N 3.31Å; I382-L384 PolarHBondContact O-N 3.23Å; L384-T388 PolarHBondContact O-N 3.45Å; L384-T388 PolarHBondContact O-OG1 2.87Å; L384-F449 HydrophobicContact CB-CD1 4.49Å; L384-F449 HydrophobicContact CB-CE1 4.45Å; L384-F449 HydrophobicContact CD1-CB 4.05Å; L384-F449 HydrophobicContact CD1-CD1 4.25Å; L384-F449 HydrophobicContact CD1-CD2 3.29Å; L384-F449 HydrophobicContact CD1-CE2 3.67Å; L384-F449 HydrophobicContact CD1-CG 3.62Å; L384-F449 HydrophobicContact CD1-CZ 4.34Å; L384-I476 HydrophobicContact CD2-CG2 3.8Å
385	G	86.7	Confident	80.8	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-63.9	-47.7	176.8	0	0	0	0	0	113.2	G125 L126 F381 I382 T388	G125-G385 VanDerWaalsContact C-C 3.48Å; G125-G385 CarbonylContact O-C 3.58Å; L126-G385 WeakPolarHBondContact CD2-O 3.47Å; F381-G385 PolarHBondContact O-N 2.88Å; I382-G385 WeakPolarHBondContact O-CA 3.29Å; I382-G385 PolarHBondContact O-N 2.98Å; G385-T388 WeakPolarHBondContact O-CB 3.41Å; G385-T388 PolarHBondContact O-N 2.75Å
386	V	83	Confident	80.5	Confident	7 Å²	7	30.2 Å²	30.2	4%	0.042	16%	0.157	C	C	.	.	H	α-helix	trans	-62.6	-49.2	179.7	173.8	0	0	0	0	111.1	G125 I128 A139 I382 T388 V389	G125-V386 VanDerWaalsContact O-CG2 3.29Å; G125-V386 WeakPolarHBondContact O-CG2 3.43Å; G125-V386 PolarHBondContact O-N 3.22Å; I128-V386 HydrophobicContact CB-CG2 4.11Å; I128-V386 HydrophobicContact CG2-CG2 3.76Å; A139-V386 HydrophobicContact CB-CG1 3.77Å; I382-V386 HydrophobicContact CG2-CG2 4.25Å; I382-V386 WeakPolarHBondContact O-CG2 3.48Å; I382-V386 PolarHBondContact O-N 3.24Å; V386-T388 PolarHBondContact O-N 2.76Å; V386-V389 PolarHBondContact O-N 3.2Å
387	S	80.4	Confident	80.2	Confident	1 Å²	1	38 Å²	38	1%	0.007	19%	0.186	C	C	.	.	H	α-helix	trans	-60.8	-28.1	-179.9	-60.7	0	0	0	0	113.1	F383 V389 E390 G391	F383-S387 WeakPolarHBondContact O-CB 3.37Å; F383-S387 PolarHBondContact O-N 3Å; F383-S387 PolarHBondContact O-OG 3.43Å; S387-V389 PolarHBondContact O-N 2.96Å; S387-E390 PolarHBondContact O-N 2.84Å; S387-G391 PolarHBondContact O-N 2.87Å
388	T	83.1	Confident	80.2	Confident	25 Å²	25	39.9 Å²	39.9	15%	0.153	20%	0.197	C	C	.	.	H	α-helix	trans	-65.6	-23.8	174.5	-60.3	0	0	0	0	112.5	L126 L384 G385 V386 H393 I473 F477	L126-T388 HydrophobicContact CD2-CG2 3.91Å; L384-T388 PolarHBondContact O-N 3.45Å; L384-T388 PolarHBondContact O-OG1 2.87Å; G385-T388 WeakPolarHBondContact O-CB 3.41Å; G385-T388 PolarHBondContact O-N 2.75Å; V386-T388 PolarHBondContact O-N 2.76Å; T388-H393 PolarHBondContact O-NE2 3.34Å; T388-I473 HydrophobicContact CG2-CG2 3.83Å; T388-F477 HydrophobicContact CG2-CE2 3.84Å; T388-F477 HydrophobicContact CG2-CZ 4.14Å; T388-F477 WeakPolarHBondContact OG1-CE2 3.01Å
389	V	82.3	Confident	80.2	Confident	28 Å²	28	39.8 Å²	39.8	17%	0.17	20%	0.196	C	C	.	.	H	α-helix	trans	-88.6	-31.2	-179.6	-177.3	0	0	0	0	112.8	L126 G129 K133 V386 S387	L126-V389 HydrophobicContact CD2-CG2 3.79Å; G129-V389 WeakPolarHBondContact O-CG1 3.45Å; K133-V389 HydrophobicContact CB-CG1 4.02Å; K133-V389 HydrophobicContact CD-CG1 3.54Å; K133-V389 HydrophobicContact CG-CG1 4.45Å; K133-V389 PolarHBondContact NZ-O 3.26Å; V386-V389 PolarHBondContact O-N 3.2Å; S387-V389 PolarHBondContact O-N 2.96Å
390	E	72.4	Confident	80.3	Confident	60 Å²	60	38.7 Å²	38.7	28%	0.28	19%	0.19	S	C	.	.	H	α-helix	trans	-94.2	-27	-177.3	-172.7	174.7	-147.1	0	0	114	K138 A139 V141 S387	K138-E390 WeakPolarHBondContact CG-OE1 3.44Å; A139-E390 VanDerWaalsContact CB-OE2 3.29Å; A139-E390 WeakPolarHBondContact CB-OE2 3.42Å; A139-E390 PolarHBondContact N-OE1 3.45Å; V141-E390 WeakPolarHBondContact CG2-OE2 3.41Å; S387-E390 PolarHBondContact O-N 2.84Å
391	G	66.1	Low	80.5	Confident	12 Å²	12	42.1 Å²	42.1	12%	0.124	21%	0.211	C	C	.	.	S	Bend	trans	-56.7	146.1	-172.1	0	0	0	0	0	115.1	S387 H393	S387-G391 PolarHBondContact O-N 2.87Å; G391-H393 PolarHBondContact O-CD2 2.85Å; G391-H393 PolarHBondContact O-N 3.18Å; G391-H393 PolarHBondContact O-NE2 3.49Å
392	P	66.2	Low	80.7	Confident	105 Å²	105	46 Å²	46	68%	0.682	23%	0.228	S	C	*	.			trans	-73.9	93.7	172.9	30.7	-33.6	0	0	0	110.2	N394	P392-N394 PolarHBondContact O-N 3.27Å
393	H	70.9	Confident	81	Confident	65 Å²	65	45.4 Å²	45.4	30%	0.301	23%	0.225	S	C	.	.			trans	-86.8	106.6	-177.1	-60.5	-70.5	0	0	0	112.3	T388 G391 W395 T470	T388-H393 PolarHBondContact O-NE2 3.34Å; G391-H393 PolarHBondContact O-CD2 2.85Å; G391-H393 PolarHBondContact O-N 3.18Å; G391-H393 PolarHBondContact O-NE2 3.49Å; H393-W395 PolarHBondContact O-N 3.06Å; H393-T470 WeakPolarHBondContact CA-OG1 3.45Å; H393-T470 HydrophobicContact CB-CG2 4.32Å
394	N	73.9	Confident	81.4	Confident	67 Å²	67	45 Å²	45	36%	0.358	23%	0.225	S	C	.	.			trans	-90.5	98.4	167.5	-168.4	-10.7	0	0	0	109.5	P392 N396 M467 T470	P392-N394 PolarHBondContact O-N 3.27Å; N394-N396 PolarHBondContact O-N 3.39Å; N394-N396 VanDerWaalsContact O-N 3.11Å; N394-M467 HydrophobicContact CB-CG 4.1Å; N394-T470 PolarHBondContact N-OG1 3.47Å
395	W	72.6	Confident	81.7	Confident	109 Å²	109	48.4 Å²	48.4	41%	0.413	25%	0.246	S	C	.	.			trans	-81.6	86.1	-170.8	-95.1	87.3	0	0	0	113.6	H393 W397 T470	H393-W395 PolarHBondContact O-N 3.06Å; W395-W397 HydrophobicContact CD2-CZ2 4.41Å; W395-W397 AromaticContact CE3-CD2 3.73Å; W395-W397 HydrophobicContact CE3-CD2 3.73Å; W395-W397 AromaticContact CE3-CE2 3.44Å; W395-W397 VanDerWaalsContact CE3-CE2 3.44Å; W395-W397 HydrophobicContact CE3-CE3 4.11Å; W395-W397 HydrophobicContact CE3-CG 4.27Å; W395-W397 AromaticContact CE3-CH2 3.99Å; W395-W397 HydrophobicContact CE3-CH2 3.99Å; W395-W397 AromaticContact CE3-CZ2 3.59Å; W395-W397 HydrophobicContact CE3-CZ2 3.59Å; W395-W397 HydrophobicContact CE3-CZ3 4.23Å; W395-W397 AromaticContact CE3-NE1 3.82Å; W395-W397 AromaticContact CH2-CH2 4Å; W395-W397 HydrophobicContact CH2-CH2 4Å; W395-W397 HydrophobicContact CH2-CZ2 4.31Å; W395-W397 HydrophobicContact CH2-CZ3 4.29Å; W395-W397 AromaticContact CZ3-CD2 3.84Å; W395-W397 HydrophobicContact CZ3-CD2 3.84Å; W395-W397 AromaticContact CZ3-CE2 3.73Å; W395-W397 AromaticContact CZ3-CE3 3.71Å; W395-W397 HydrophobicContact CZ3-CE3 3.71Å; W395-W397 AromaticContact CZ3-CH2 3.41Å; W395-W397 HydrophobicContact CZ3-CH2 3.41Å; W395-W397 VanDerWaalsContact CZ3-CH2 3.41Å; W395-W397 AromaticContact CZ3-CZ2 3.54Å; W395-W397 HydrophobicContact CZ3-CZ2 3.54Å; W395-W397 AromaticContact CZ3-CZ3 3.5Å; W395-W397 HydrophobicContact CZ3-CZ3 3.5Å; W395-W397 PolarHBondContact O-N 3.19Å; W395-T470 HydrophobicContact CD2-CG2 4.05Å; W395-T470 HydrophobicContact CG-CG2 4.16Å; W395-T470 HydrophobicContact CZ2-CG2 4.31Å
396	N	81.4	Confident	82	Confident	20 Å²	20	49.8 Å²	49.8	11%	0.107	25%	0.252	C	S	.	.			trans	-90.2	91.7	165.3	-171.9	-26.1	0	0	0	110.9	A203 N394 I398 F399 V400 M467	A203-N396 PolarHBondContact O-ND2 3.34Å; N394-N396 PolarHBondContact O-N 3.39Å; N394-N396 VanDerWaalsContact O-N 3.11Å; N396-I398 PolarHBondContact O-N 2.67Å; N396-I398 PolarHBondContact OD1-N 2.89Å; N396-F399 HydrophobicContact CB-CB 3.97Å; N396-F399 PolarHBondContact O-N 2.87Å; N396-F399 PolarHBondContact OD1-N 3.4Å; N396-F399 VanDerWaalsContact OD1-N 3.08Å; N396-V400 VanDerWaalsContact O-CG2 3.32Å; N396-V400 WeakPolarHBondContact O-CG2 3.26Å; N396-V400 PolarHBondContact O-N 3.43Å; N396-M467 HydrophobicContact CB-CG 4.42Å; N396-M467 HydrophobicContact CB-SD 3.95Å
397	W	82.8	Confident	82.4	Confident	165 Å²	165	49.8 Å²	49.8	63%	0.625	25%	0.252	S	S	*	.	H	α-helix	trans	-55.5	-36.2	-179.7	-74.1	94.6	0	0	0	113.9	W395 V401	W395-W397 HydrophobicContact CD2-CZ2 4.41Å; W395-W397 AromaticContact CE3-CD2 3.73Å; W395-W397 HydrophobicContact CE3-CD2 3.73Å; W395-W397 AromaticContact CE3-CE2 3.44Å; W395-W397 VanDerWaalsContact CE3-CE2 3.44Å; W395-W397 HydrophobicContact CE3-CE3 4.11Å; W395-W397 HydrophobicContact CE3-CG 4.27Å; W395-W397 AromaticContact CE3-CH2 3.99Å; W395-W397 HydrophobicContact CE3-CH2 3.99Å; W395-W397 AromaticContact CE3-CZ2 3.59Å; W395-W397 HydrophobicContact CE3-CZ2 3.59Å; W395-W397 HydrophobicContact CE3-CZ3 4.23Å; W395-W397 AromaticContact CE3-NE1 3.82Å; W395-W397 AromaticContact CH2-CH2 4Å; W395-W397 HydrophobicContact CH2-CH2 4Å; W395-W397 HydrophobicContact CH2-CZ2 4.31Å; W395-W397 HydrophobicContact CH2-CZ3 4.29Å; W395-W397 AromaticContact CZ3-CD2 3.84Å; W395-W397 HydrophobicContact CZ3-CD2 3.84Å; W395-W397 AromaticContact CZ3-CE2 3.73Å; W395-W397 AromaticContact CZ3-CE3 3.71Å; W395-W397 HydrophobicContact CZ3-CE3 3.71Å; W395-W397 AromaticContact CZ3-CH2 3.41Å; W395-W397 HydrophobicContact CZ3-CH2 3.41Å; W395-W397 VanDerWaalsContact CZ3-CH2 3.41Å; W395-W397 AromaticContact CZ3-CZ2 3.54Å; W395-W397 HydrophobicContact CZ3-CZ2 3.54Å; W395-W397 AromaticContact CZ3-CZ3 3.5Å; W395-W397 HydrophobicContact CZ3-CZ3 3.5Å; W395-W397 PolarHBondContact O-N 3.19Å; W397-V401 WeakPolarHBondContact O-CB 3.35Å; W397-V401 VanDerWaalsContact O-CG2 3.26Å; W397-V401 WeakPolarHBondContact O-CG2 3.15Å; W397-V401 PolarHBondContact O-N 2.99Å
398	I	86.2	Confident	82.9	Confident	73 Å²	73	52.7 Å²	52.7	37%	0.374	27%	0.267	S	S	.	.	H	α-helix	trans	-65.1	-52.7	180	-63.8	170.8	0	0	0	109.1	A202 A203 N396 V400 V401 F402	A202-I398 VanDerWaalsContact O-CD1 3.3Å; A202-I398 WeakPolarHBondContact O-CD1 3.45Å; A203-I398 HydrophobicContact CB-CG2 4.4Å; N396-I398 PolarHBondContact O-N 2.67Å; N396-I398 PolarHBondContact OD1-N 2.89Å; I398-V400 PolarHBondContact O-N 2.97Å; I398-V401 PolarHBondContact O-N 2.88Å; I398-F402 HydrophobicContact CG2-CD2 3.75Å; I398-F402 HydrophobicContact CG2-CE2 3.83Å; I398-F402 VanDerWaalsContact O-CD2 3.29Å; I398-F402 WeakPolarHBondContact O-CD2 3.12Å; I398-F402 PolarHBondContact O-N 3.07Å
399	F	84.8	Confident	83.3	Confident	2 Å²	2	55 Å²	55	1%	0.009	28%	0.278	C	S	.	.	H	α-helix	trans	-58.8	-45.6	178.6	-174.8	-96.2	0	0	0	112.2	M194 F216 N396 T403 F468 A471	M194-F399 HydrophobicContact SD-CD2 4.02Å; M194-F399 HydrophobicContact SD-CE2 3.58Å; M194-F399 VanDerWaalsContact SD-CE2 3.58Å; M194-F399 HydrophobicContact SD-CZ 3.87Å; F216-F399 HydrophobicContact CD1-CZ 4.21Å; F216-F399 AromaticContact CE1-CE1 3.97Å; F216-F399 HydrophobicContact CE1-CE1 3.97Å; F216-F399 AromaticContact CE1-CZ 3.67Å; F216-F399 HydrophobicContact CE1-CZ 3.67Å; F216-F399 HydrophobicContact CE2-CE1 4.23Å; F216-F399 HydrophobicContact CE2-CZ 4.45Å; F216-F399 AromaticContact CZ-CE1 3.61Å; F216-F399 HydrophobicContact CZ-CE1 3.61Å; F216-F399 AromaticContact CZ-CZ 3.79Å; F216-F399 HydrophobicContact CZ-CZ 3.79Å; N396-F399 HydrophobicContact CB-CB 3.97Å; N396-F399 PolarHBondContact O-N 2.87Å; N396-F399 PolarHBondContact OD1-N 3.4Å; N396-F399 VanDerWaalsContact OD1-N 3.08Å; F399-T403 WeakPolarHBondContact O-CB 3.47Å; F399-T403 PolarHBondContact O-N 3.22Å; F399-T403 PolarHBondContact O-OG1 3.44Å; F399-F468 AromaticContact CE1-CD1 3.85Å; F399-F468 HydrophobicContact CE1-CD1 3.85Å; F399-F468 HydrophobicContact CE1-CE1 4.26Å; F399-F468 HydrophobicContact CE2-CE1 4.26Å; F399-F468 AromaticContact CZ-CD1 3.66Å; F399-F468 HydrophobicContact CZ-CD1 3.66Å; F399-F468 AromaticContact CZ-CE1 3.6Å; F399-F468 HydrophobicContact CZ-CE1 3.6Å; F399-A471 HydrophobicContact CD1-CB 4Å; F399-A471 HydrophobicContact CE1-CB 3.81Å
400	V	88.1	Confident	83.8	Confident	5 Å²	5	53.7 Å²	53.7	3%	0.03	27%	0.27	C	S	.	.	H	α-helix	trans	-64.4	-45.4	-179.3	174.7	0	0	0	0	112	N396 I398 T403 L404 A471 T474	N396-V400 VanDerWaalsContact O-CG2 3.32Å; N396-V400 WeakPolarHBondContact O-CG2 3.26Å; N396-V400 PolarHBondContact O-N 3.43Å; I398-V400 PolarHBondContact O-N 2.97Å; V400-T403 WeakPolarHBondContact O-CB 3.39Å; V400-T403 PolarHBondContact O-N 3.27Å; V400-L404 PolarHBondContact O-N 3.45Å; V400-A471 HydrophobicContact CG2-CB 4.06Å; V400-T474 HydrophobicContact CG1-CG2 3.56Å
401	V	90	Very high	84.7	Confident	82 Å²	82	51.5 Å²	51.5	50%	0.497	26%	0.259	S	S	.	.	H	α-helix	trans	-67.4	-43.6	-179.9	171.1	0	0	0	0	111.3	W397 I398 T403 L404 V405	W397-V401 WeakPolarHBondContact O-CB 3.35Å; W397-V401 VanDerWaalsContact O-CG2 3.26Å; W397-V401 WeakPolarHBondContact O-CG2 3.15Å; W397-V401 PolarHBondContact O-N 2.99Å; I398-V401 PolarHBondContact O-N 2.88Å; V401-T403 PolarHBondContact O-N 2.96Å; V401-L404 PolarHBondContact O-N 2.88Å; V401-V405 WeakPolarHBondContact O-CG2 3.08Å; V401-V405 PolarHBondContact O-N 2.87Å
402	F	90.1	Very high	85.9	Confident	85 Å²	85	54.4 Å²	54.4	37%	0.373	27%	0.274	S	S	.	.	H	α-helix	trans	-64.1	-39.6	174.9	-82.1	-67.2	0	0	0	112.1	M194 V197 I398 L404 V405 F406	M194-F402 HydrophobicContact CE-CB 3.55Å; V197-F402 HydrophobicContact CG1-CB 4.44Å; V197-F402 HydrophobicContact CG1-CD2 3.99Å; V197-F402 HydrophobicContact CG1-CG 4.34Å; V197-F402 HydrophobicContact CG2-CB 4.31Å; V197-F402 HydrophobicContact CG2-CD1 4.28Å; V197-F402 HydrophobicContact CG2-CD2 4.36Å; V197-F402 HydrophobicContact CG2-CG 4.09Å; I398-F402 HydrophobicContact CG2-CD2 3.75Å; I398-F402 HydrophobicContact CG2-CE2 3.83Å; I398-F402 VanDerWaalsContact O-CD2 3.29Å; I398-F402 WeakPolarHBondContact O-CD2 3.12Å; I398-F402 PolarHBondContact O-N 3.07Å; F402-L404 VanDerWaalsContact C-N 3.33Å; F402-L404 PolarHBondContact O-N 2.77Å; F402-V405 PolarHBondContact O-N 3.25Å; F402-F406 HydrophobicContact CB-CD2 4.48Å; F402-F406 HydrophobicContact CB-CE2 4.17Å; F402-F406 HydrophobicContact CD1-CE1 4.35Å; F402-F406 HydrophobicContact CD1-CE2 4.15Å; F402-F406 AromaticContact CD1-CZ 3.8Å; F402-F406 HydrophobicContact CD1-CZ 3.8Å; F402-F406 HydrophobicContact CE1-CZ 4.46Å; F402-F406 WeakPolarHBondContact O-CB 3.48Å; F402-F406 WeakPolarHBondContact O-CD2 3.43Å; F402-F406 VanDerWaalsContact O-CG 3.32Å; F402-F406 WeakPolarHBondContact O-CG 3.3Å; F402-F406 PolarHBondContact O-N 3.41Å
403	T	90.2	Very high	87.2	Confident	0 Å²	0	53.1 Å²	53.1	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-55.9	-48.8	173.7	-58.4	0	0	0	0	110.8	M194 F216 I220 F399 V400 V401 F406 C407 V475	M194-T403 PolarHBondContact SD-OG1 3.42Å; F216-T403 HydrophobicContact CE1-CG2 3.82Å; F216-T403 HydrophobicContact CZ-CG2 3.74Å; I220-T403 HydrophobicContact CD1-CG2 3.58Å; F399-T403 WeakPolarHBondContact O-CB 3.47Å; F399-T403 PolarHBondContact O-N 3.22Å; F399-T403 PolarHBondContact O-OG1 3.44Å; V400-T403 WeakPolarHBondContact O-CB 3.39Å; V400-T403 PolarHBondContact O-N 3.27Å; V401-T403 PolarHBondContact O-N 2.96Å; T403-F406 PolarHBondContact O-N 3.5Å; T403-C407 WeakPolarHBondContact O-CB 2.98Å; T403-C407 PolarHBondContact O-N 3.08Å; T403-V475 HydrophobicContact CG2-CG2 3.92Å
404	L	91.8	Very high	88.1	Confident	34 Å²	34	50.2 Å²	50.2	18%	0.178	25%	0.249	C	C	.	.	H	α-helix	trans	-61.9	-47.9	-179.6	-174	160.4	0	0	0	111.4	V400 V401 F402 C407 L408 V475 F478	V400-L404 PolarHBondContact O-N 3.45Å; V401-L404 PolarHBondContact O-N 2.88Å; F402-L404 VanDerWaalsContact C-N 3.33Å; F402-L404 PolarHBondContact O-N 2.77Å; L404-C407 PolarHBondContact O-N 3.36Å; L404-L408 HydrophobicContact CD2-CD1 3.83Å; L404-L408 WeakPolarHBondContact O-CG 3.13Å; L404-L408 PolarHBondContact O-N 2.74Å; L404-L408 VanDerWaalsContact O-N 3.11Å; L404-V475 HydrophobicContact CB-CG2 4.46Å; L404-F478 HydrophobicContact CD1-CB 3.9Å; L404-F478 HydrophobicContact CD1-CD1 4.02Å; L404-F478 HydrophobicContact CD1-CD2 3.8Å; L404-F478 HydrophobicContact CD1-CE2 4.33Å; L404-F478 HydrophobicContact CD1-CG 3.62Å; L404-F478 HydrophobicContact CD2-CD1 4.27Å; L404-F478 HydrophobicContact CD2-CE1 4.09Å; L404-F478 HydrophobicContact CD2-CZ 4.22Å; L404-F478 HydrophobicContact CG-CD1 4.09Å; L404-F478 HydrophobicContact CG-CE1 4.43Å; L404-F478 HydrophobicContact CG-CG 4.21Å
405	V	92.6	Very high	88.9	Confident	72 Å²	72	47.2 Å²	47.2	44%	0.436	23%	0.233	S	C	.	.	H	α-helix	trans	-62.5	-46.6	179.1	171.6	0	0	0	0	111.3	V401 F402 L408 L409	V401-V405 WeakPolarHBondContact O-CG2 3.08Å; V401-V405 PolarHBondContact O-N 2.87Å; F402-V405 PolarHBondContact O-N 3.25Å; V405-L408 PolarHBondContact O-N 2.84Å; V405-L409 WeakPolarHBondContact O-CB 3.44Å; V405-L409 PolarHBondContact O-N 3.21Å
406	F	92.6	Very high	89.7	Confident	29 Å²	29	45.5 Å²	45.5	13%	0.127	24%	0.235	C	C	.	.	H	α-helix	trans	-70.3	-31.6	178.7	-62.7	-27.9	0	0	0	112.8	M193 M194 V197 F402 T403 L409 S410	M193-F406 HydrophobicContact CB-CD2 3.52Å; M193-F406 HydrophobicContact CB-CE2 3.66Å; M193-F406 HydrophobicContact CB-CG 4.05Å; M193-F406 HydrophobicContact CB-CZ 4.29Å; M193-F406 HydrophobicContact CG-CD2 4.46Å; M194-F406 HydrophobicContact CE-CD2 3.4Å; M194-F406 VanDerWaalsContact CE-CD2 3.4Å; M194-F406 HydrophobicContact CE-CE2 3.58Å; V197-F406 HydrophobicContact CG2-CE2 3.65Å; V197-F406 HydrophobicContact CG2-CZ 4.07Å; F402-F406 HydrophobicContact CB-CD2 4.48Å; F402-F406 HydrophobicContact CB-CE2 4.17Å; F402-F406 HydrophobicContact CD1-CE1 4.35Å; F402-F406 HydrophobicContact CD1-CE2 4.15Å; F402-F406 AromaticContact CD1-CZ 3.8Å; F402-F406 HydrophobicContact CD1-CZ 3.8Å; F402-F406 HydrophobicContact CE1-CZ 4.46Å; F402-F406 WeakPolarHBondContact O-CB 3.48Å; F402-F406 WeakPolarHBondContact O-CD2 3.43Å; F402-F406 VanDerWaalsContact O-CG 3.32Å; F402-F406 WeakPolarHBondContact O-CG 3.3Å; F402-F406 PolarHBondContact O-N 3.41Å; T403-F406 PolarHBondContact O-N 3.5Å; F406-L409 PolarHBondContact O-N 3.19Å; F406-S410 WeakPolarHBondContact O-CA 3.47Å; F406-S410 WeakPolarHBondContact O-CB 3.34Å; F406-S410 PolarHBondContact O-N 3.33Å
407	C	91.1	Very high	90.2	Very high	7 Å²	7	46.1 Å²	46.1	5%	0.047	25%	0.246	C	C	.	.	H	α-helix	trans	-60.4	-47.3	172.4	179.1	0	0	0	0	111.3	I190 T403 L404 R411 R444	I190-C407 HydrophobicContact CD1-CB 4.43Å; T403-C407 WeakPolarHBondContact O-CB 2.98Å; T403-C407 PolarHBondContact O-N 3.08Å; L404-C407 PolarHBondContact O-N 3.36Å; C407-R411 WeakPolarHBondContact O-CB 3.27Å; C407-R411 PolarHBondContact O-N 2.85Å; C407-R444 PolarHBondContact SG-NE 2.94Å; C407-R444 PolarHBondContact SG-NH2 2.76Å
408	L	90.9	Very high	90.4	Very high	61 Å²	61	39 Å²	39	32%	0.319	22%	0.22	S	C	.	.	H	α-helix	trans	-65.7	-44.7	176.1	-65.8	175.8	0	0	0	112.1	L404 V405 R411 V412 F478	L404-L408 HydrophobicContact CD2-CD1 3.83Å; L404-L408 WeakPolarHBondContact O-CG 3.13Å; L404-L408 PolarHBondContact O-N 2.74Å; L404-L408 VanDerWaalsContact O-N 3.11Å; V405-L408 PolarHBondContact O-N 2.84Å; L408-R411 PolarHBondContact O-N 3.32Å; L408-V412 WeakPolarHBondContact O-CG2 3.43Å; L408-V412 PolarHBondContact O-N 3.49Å; L408-V412 VanDerWaalsContact O-N 3.14Å; L408-F478 HydrophobicContact CD1-CE1 3.94Å; L408-F478 HydrophobicContact CD1-CZ 4.37Å; L408-F478 HydrophobicContact CD2-CE1 4.3Å
409	L	93.2	Very high	90.5	Very high	75 Å²	75	35.6 Å²	35.6	39%	0.393	20%	0.202	S	C	.	.	H	α-helix	trans	-64.9	-46.7	-179.6	-178.1	63.2	0	0	0	111.9	F189 V405 F406 R411 V412 L413	F189-L409 HydrophobicContact CZ-CD2 4.26Å; F189-L409 HydrophobicContact CZ-CG 4.43Å; V405-L409 WeakPolarHBondContact O-CB 3.44Å; V405-L409 PolarHBondContact O-N 3.21Å; F406-L409 PolarHBondContact O-N 3.19Å; L409-R411 VanDerWaalsContact C-N 3.3Å; L409-R411 PolarHBondContact O-N 3.34Å; L409-V412 PolarHBondContact O-N 2.95Å; L409-L413 HydrophobicContact CD1-CD1 3.9Å; L409-L413 HydrophobicContact CD1-CG 4Å; L409-L413 HydrophobicContact CD2-CD1 4.42Å; L409-L413 HydrophobicContact CG-CD1 3.8Å; L409-L413 HydrophobicContact CG-CG 4.27Å; L409-L413 WeakPolarHBondContact O-CB 3.48Å; L409-L413 WeakPolarHBondContact O-CG 3.44Å; L409-L413 PolarHBondContact O-N 2.92Å
410	S	91.8	Very high	90.6	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57	-44.5	178.1	-172.4	0	0	0	0	111.2	W185 N186 F189 F406 L413 G414	W185-S410 PolarHBondContact NE1-O 3.29Å; N186-S410 PolarHBondContact OD1-OG 3.42Å; F189-S410 VanDerWaalsContact CD1-CB 3.42Å; F189-S410 WeakPolarHBondContact CD1-OG 3.29Å; F406-S410 WeakPolarHBondContact O-CA 3.47Å; F406-S410 WeakPolarHBondContact O-CB 3.34Å; F406-S410 PolarHBondContact O-N 3.33Å; S410-L413 PolarHBondContact O-N 2.72Å; S410-G414 WeakPolarHBondContact O-CA 3.37Å; S410-G414 PolarHBondContact O-N 3.03Å
411	R	90.6	Very high	90.4	Very high	13 Å²	13	47.6 Å²	47.6	5%	0.049	26%	0.258	C	S	.	.	H	α-helix	trans	-61.2	-47.7	177.2	-174.5	69.4	-173.4	166.9	8.4	112.2	E248 C407 L408 L409 V415 V438 A439	E248-R411 IonicContact OE1-CZ 2.65Å; E248-R411 IonicContact OE1-NH1 3.07Å; E248-R411 PolarHBondContact OE1-NH1 3.49Å; E248-R411 IonicContact OE1-NH2 2.64Å; E248-R411 PolarHBondContact OE1-NH2 3.3Å; E248-R411 IonicContact OE2-NH2 3.4Å; E248-R411 PolarHBondContact OE2-NH2 3.25Å; C407-R411 WeakPolarHBondContact O-CB 3.27Å; C407-R411 PolarHBondContact O-N 2.85Å; L408-R411 PolarHBondContact O-N 3.32Å; L409-R411 VanDerWaalsContact C-N 3.3Å; L409-R411 PolarHBondContact O-N 3.34Å; R411-V415 WeakPolarHBondContact O-CB 3.13Å; R411-V415 WeakPolarHBondContact O-CG2 3.25Å; R411-V415 PolarHBondContact O-N 3.44Å; R411-V438 PolarHBondContact NH2-O 3.08Å; R411-A439 WeakPolarHBondContact CG-O 3.38Å
412	V	91.7	Very high	90.2	Very high	73 Å²	73	44.3 Å²	44.3	44%	0.442	24%	0.238	S	C	.	.	H	α-helix	trans	-65.5	-47.7	179	173.9	0	0	0	0	111.1	L408 L409 V416 A439	L408-V412 WeakPolarHBondContact O-CG2 3.43Å; L408-V412 PolarHBondContact O-N 3.49Å; L408-V412 VanDerWaalsContact O-N 3.14Å; L409-V412 PolarHBondContact O-N 2.95Å; V412-V416 HydrophobicContact CG1-CG2 4.48Å; V412-V416 WeakPolarHBondContact O-CB 3.24Å; V412-V416 VanDerWaalsContact O-CG2 3.25Å; V412-V416 WeakPolarHBondContact O-CG2 3.13Å; V412-V416 PolarHBondContact O-N 2.9Å; V412-A439 HydrophobicContact CG2-CB 4.41Å
413	L	92.8	Very high	89.9	Confident	78 Å²	78	42.4 Å²	42.4	41%	0.408	23%	0.231	S	C	.	.	H	α-helix	trans	-64.3	-42.4	178.9	-67.8	178.5	0	0	0	112	W185 F189 L409 S410 G417	W185-L413 HydrophobicContact CZ2-CB 4.32Å; F189-L413 HydrophobicContact CE2-CD1 4.05Å; F189-L413 HydrophobicContact CZ-CD1 3.96Å; L409-L413 HydrophobicContact CD1-CD1 3.9Å; L409-L413 HydrophobicContact CD1-CG 4Å; L409-L413 HydrophobicContact CD2-CD1 4.42Å; L409-L413 HydrophobicContact CG-CD1 3.8Å; L409-L413 HydrophobicContact CG-CG 4.27Å; L409-L413 WeakPolarHBondContact O-CB 3.48Å; L409-L413 WeakPolarHBondContact O-CG 3.44Å; L409-L413 PolarHBondContact O-N 2.92Å; S410-L413 PolarHBondContact O-N 2.72Å; L413-G417 PolarHBondContact O-N 2.93Å
414	G	90.5	Very high	89.4	Confident	4 Å²	4	50.8 Å²	50.8	4%	0.041	27%	0.268	C	S	.	.	H	α-helix	trans	-62.6	-52.1	178.3	0	0	0	0	0	111.7	S410 V416 G417 L418	S410-G414 WeakPolarHBondContact O-CA 3.37Å; S410-G414 PolarHBondContact O-N 3.03Å; G414-V416 PolarHBondContact O-N 2.88Å; G414-G417 PolarHBondContact O-N 3.38Å; G414-L418 VanDerWaalsContact O-CB 3.3Å; G414-L418 WeakPolarHBondContact O-CB 3.4Å; G414-L418 WeakPolarHBondContact O-CD1 3.26Å; G414-L418 WeakPolarHBondContact O-CG 3.49Å; G414-L418 PolarHBondContact O-N 3.2Å
415	V	90.6	Very high	88.5	Confident	4 Å²	4	57.2 Å²	57.2	2%	0.024	29%	0.294	C	S	.	.	H	α-helix	trans	-63.3	-43.6	178.3	174.4	0	0	0	0	111.2	R411 T419 V438 A439	R411-V415 WeakPolarHBondContact O-CB 3.13Å; R411-V415 WeakPolarHBondContact O-CG2 3.25Å; R411-V415 PolarHBondContact O-N 3.44Å; V415-T419 HydrophobicContact CG1-CG2 4.04Å; V415-T419 WeakPolarHBondContact O-CB 3.27Å; V415-T419 WeakPolarHBondContact O-CG2 3.49Å; V415-T419 PolarHBondContact O-N 3.16Å; V415-T419 PolarHBondContact O-OG1 3.46Å; V415-V438 HydrophobicContact CG1-CB 4.26Å; V415-V438 HydrophobicContact CG1-CG1 4.03Å; V415-V438 HydrophobicContact CG2-CG1 4.19Å; V415-A439 HydrophobicContact CB-CB 4.1Å; V415-A439 HydrophobicContact CG1-CB 4.21Å; V415-A439 HydrophobicContact CG2-CB 4.29Å
416	V	90.8	Very high	87.3	Confident	74 Å²	74	55.5 Å²	55.5	45%	0.448	28%	0.28	S	S	.	.	H	α-helix	trans	-65.8	-41.6	178	173.3	0	0	0	0	112	V412 G414 T419 F420	V412-V416 HydrophobicContact CG1-CG2 4.48Å; V412-V416 WeakPolarHBondContact O-CB 3.24Å; V412-V416 VanDerWaalsContact O-CG2 3.25Å; V412-V416 WeakPolarHBondContact O-CG2 3.13Å; V412-V416 PolarHBondContact O-N 2.9Å; G414-V416 PolarHBondContact O-N 2.88Å; V416-T419 WeakPolarHBondContact CA-OG1 3.44Å; V416-T419 PolarHBondContact O-OG1 3.36Å; V416-T419 VanDerWaalsContact O-OG1 3.06Å; V416-F420 WeakPolarHBondContact O-CB 3.39Å; V416-F420 PolarHBondContact O-N 3.26Å
417	G	90.2	Very high	85.5	Confident	33 Å²	33	62.2 Å²	62.2	34%	0.34	32%	0.315	S	S	.	.	H	α-helix	trans	-66.7	-49.5	178.3	0	0	0	0	0	113.1	L413 G414 F420 I421	L413-G417 PolarHBondContact O-N 2.93Å; G414-G417 PolarHBondContact O-N 3.38Å; G417-F420 WeakPolarHBondContact O-CB 3.5Å; G417-F420 PolarHBondContact O-N 2.93Å; G417-I421 WeakPolarHBondContact O-CG1 3.45Å; G417-I421 PolarHBondContact O-N 3.2Å
418	L	88.4	Confident	84.3	Confident	14 Å²	14	65.8 Å²	65.8	7%	0.073	34%	0.337	C	S	.	.	H	α-helix	trans	-64	-43.6	177.5	-64.7	164	0	0	0	111	V177 F178 V181 G414 F420 I421 I422	V177-L418 HydrophobicContact CG1-CD2 3.98Å; F178-L418 HydrophobicContact CD1-CB 4.28Å; F178-L418 HydrophobicContact CD1-CD1 3.91Å; F178-L418 HydrophobicContact CE1-CB 3.88Å; F178-L418 HydrophobicContact CE1-CD1 4.26Å; V181-L418 HydrophobicContact CB-CD2 4.02Å; V181-L418 HydrophobicContact CG1-CD2 3.86Å; G414-L418 VanDerWaalsContact O-CB 3.3Å; G414-L418 WeakPolarHBondContact O-CB 3.4Å; G414-L418 WeakPolarHBondContact O-CD1 3.26Å; G414-L418 WeakPolarHBondContact O-CG 3.49Å; G414-L418 PolarHBondContact O-N 3.2Å; L418-F420 VanDerWaalsContact C-N 3.31Å; L418-F420 PolarHBondContact O-N 3.01Å; L418-I421 PolarHBondContact O-N 3.49Å; L418-I422 HydrophobicContact CB-CD1 4.29Å; L418-I422 WeakPolarHBondContact O-CB 3.33Å; L418-I422 WeakPolarHBondContact O-CD1 3.29Å; L418-I422 WeakPolarHBondContact O-CG1 3.24Å; L418-I422 PolarHBondContact O-N 3.26Å
419	T	86.9	Confident	83.4	Confident	2 Å²	2	69.5 Å²	69.5	1%	0.012	35%	0.351	C	S	.	.	H	α-helix	trans	-64.6	-35.2	177.5	58.5	0	0	0	0	111.7	F178 V415 V416 N423 L430 Q435	F178-T419 HydrophobicContact CE1-CG2 3.98Å; F178-T419 HydrophobicContact CZ-CG2 3.57Å; V415-T419 HydrophobicContact CG1-CG2 4.04Å; V415-T419 WeakPolarHBondContact O-CB 3.27Å; V415-T419 WeakPolarHBondContact O-CG2 3.49Å; V415-T419 PolarHBondContact O-N 3.16Å; V415-T419 PolarHBondContact O-OG1 3.46Å; V416-T419 WeakPolarHBondContact CA-OG1 3.44Å; V416-T419 PolarHBondContact O-OG1 3.36Å; V416-T419 VanDerWaalsContact O-OG1 3.06Å; T419-N423 WeakPolarHBondContact O-CB 3.24Å; T419-N423 PolarHBondContact O-N 3.27Å; T419-L430 HydrophobicContact CG2-CD1 4.12Å; T419-Q435 HydrophobicContact CG2-CG 3.89Å; T419-Q435 PolarHBondContact OG1-NE2 3.11Å
420	F	86.7	Confident	82.6	Confident	166 Å²	166	66.9 Å²	66.9	73%	0.728	34%	0.337	S	S	*	.	H	α-helix	trans	-59.4	-45.5	172.4	178.1	-99.3	0	0	0	112	V416 G417 L418	V416-F420 WeakPolarHBondContact O-CB 3.39Å; V416-F420 PolarHBondContact O-N 3.26Å; G417-F420 WeakPolarHBondContact O-CB 3.5Å; G417-F420 PolarHBondContact O-N 2.93Å; L418-F420 VanDerWaalsContact C-N 3.31Å; L418-F420 PolarHBondContact O-N 3.01Å
421	I	85.8	Confident	82.2	Confident	94 Å²	94	70.5 Å²	70.5	48%	0.482	36%	0.359	S	S	.	.	H	α-helix	trans	-65	-53.1	177	-63	167.7	0	0	0	110.7	G417 L418 N423 K424 F425	G417-I421 WeakPolarHBondContact O-CG1 3.45Å; G417-I421 PolarHBondContact O-N 3.2Å; L418-I421 PolarHBondContact O-N 3.49Å; I421-N423 VanDerWaalsContact C-N 3.28Å; I421-N423 PolarHBondContact O-N 3.41Å; I421-K424 VanDerWaalsContact O-CB 3.29Å; I421-K424 WeakPolarHBondContact O-CB 3.34Å; I421-K424 PolarHBondContact O-N 3.25Å; I421-K424 VanDerWaalsContact O-N 3.09Å; I421-F425 HydrophobicContact CG2-CD2 4.48Å; I421-F425 HydrophobicContact CG2-CE2 4.17Å; I421-F425 WeakPolarHBondContact O-CD2 3.32Å
422	I	84.1	Confident	81.9	Confident	13 Å²	13	78.3 Å²	78.3	7%	0.067	39%	0.393	C	S	.	.	H	α-helix	trans	-59.9	-39	-177.9	-66.9	161	0	0	0	111.2	T174 V177 F178 L418 K424 F425 R426	T174-I422 HydrophobicContact CG2-CD1 4.37Å; T174-I422 HydrophobicContact CG2-CG2 4.08Å; V177-I422 HydrophobicContact CB-CD1 4.25Å; V177-I422 HydrophobicContact CG1-CD1 3.81Å; V177-I422 HydrophobicContact CG1-CG1 4.03Å; F178-I422 HydrophobicContact CD2-CD1 4.05Å; F178-I422 HydrophobicContact CE1-CD1 4.21Å; F178-I422 HydrophobicContact CE2-CD1 3.48Å; F178-I422 VanDerWaalsContact CE2-CD1 3.48Å; F178-I422 HydrophobicContact CZ-CD1 3.57Å; L418-I422 HydrophobicContact CB-CD1 4.29Å; L418-I422 WeakPolarHBondContact O-CB 3.33Å; L418-I422 WeakPolarHBondContact O-CD1 3.29Å; L418-I422 WeakPolarHBondContact O-CG1 3.24Å; L418-I422 PolarHBondContact O-N 3.26Å; I422-K424 PolarHBondContact O-N 2.92Å; I422-F425 PolarHBondContact O-N 3Å; I422-R426 HydrophobicContact CG2-CB 4.36Å; I422-R426 WeakPolarHBondContact O-CB 3.03Å; I422-R426 PolarHBondContact O-N 2.84Å
423	N	84.4	Confident	81.5	Confident	44 Å²	44	78.6 Å²	78.6	24%	0.235	39%	0.389	C	S	.	.	H	α-helix	trans	-69.3	-10.3	-179.3	-164.7	38.9	0	0	0	114	T419 I421 K429	T419-N423 WeakPolarHBondContact O-CB 3.24Å; T419-N423 PolarHBondContact O-N 3.27Å; I421-N423 VanDerWaalsContact C-N 3.28Å; I421-N423 PolarHBondContact O-N 3.41Å; N423-K429 VanDerWaalsContact OD1-CA 3.3Å; N423-K429 WeakPolarHBondContact OD1-CA 3.46Å; N423-K429 WeakPolarHBondContact OD1-CB 3.36Å; N423-K429 VanDerWaalsContact OD1-CD 3.24Å; N423-K429 WeakPolarHBondContact OD1-CD 3.03Å; N423-K429 WeakPolarHBondContact OD1-CG 3.02Å
424	K	79.8	Confident	81.1	Confident	176 Å²	176	76.7 Å²	76.7	77%	0.765	38%	0.379	S	S	*	.	H	α-helix	trans	-79.9	-32.3	168.3	-170.2	178.5	178.1	-179	0	112.2	I421 I422	I421-K424 VanDerWaalsContact O-CB 3.29Å; I421-K424 WeakPolarHBondContact O-CB 3.34Å; I421-K424 PolarHBondContact O-N 3.25Å; I421-K424 VanDerWaalsContact O-N 3.09Å; I422-K424 PolarHBondContact O-N 2.92Å
425	F	72.5	Confident	81	Confident	169 Å²	169	77.8 Å²	77.8	74%	0.741	38%	0.383	S	S	*	.	H	α-helix	trans	-100.4	-13.7	-176.1	-62.5	-75.9	0	0	0	114.1	I421 I422	I421-F425 HydrophobicContact CG2-CD2 4.48Å; I421-F425 HydrophobicContact CG2-CE2 4.17Å; I421-F425 WeakPolarHBondContact O-CD2 3.32Å; I422-F425 PolarHBondContact O-N 3Å
426	R	68.9	Low	80.9	Confident	36 Å²	36	82.3 Å²	82.3	14%	0.136	40%	0.402	C	S	.	.			trans	-100.6	135.6	-174.2	-160.7	174.4	-177.9	-141.3	14.6	113	N171 I422 V428	N171-R426 PolarHBondContact OD1-NH2 3.3Å; I422-R426 HydrophobicContact CG2-CB 4.36Å; I422-R426 WeakPolarHBondContact O-CB 3.03Å; I422-R426 PolarHBondContact O-N 2.84Å; R426-V428 WeakPolarHBondContact CD-O 3.28Å; R426-V428 WeakPolarHBondContact CG-O 3.34Å; R426-V428 PolarHBondContact NE-O 2.86Å; R426-V428 PolarHBondContact NH1-O 2.82Å; R426-V428 VanDerWaalsContact NH1-O 3.13Å
427	I	54.5	Low	80.6	Confident	170 Å²	170	79.4 Å²	79.4	87%	0.872	38%	0.384	S	S	*	.	S	Bend	trans	-68.9	-45.2	175.8	-56.8	167.4	0	0	0	110.6
428	V	64.6	Low	80.4	Confident	83 Å²	83	78 Å²	78	50%	0.503	37%	0.369	S	S	.	.	S	Bend	trans	-91.9	106.1	176	-177.7	0	0	0	0	110.3	L240 R426	L240-V428 HydrophobicContact CD1-CG1 4.25Å; R426-V428 WeakPolarHBondContact CD-O 3.28Å; R426-V428 WeakPolarHBondContact CG-O 3.34Å; R426-V428 PolarHBondContact NE-O 2.86Å; R426-V428 PolarHBondContact NH1-O 2.82Å; R426-V428 VanDerWaalsContact NH1-O 3.13Å
429	K	72.8	Confident	80.4	Confident	138 Å²	138	77.8 Å²	77.8	60%	0.6	37%	0.369	S	S	*	.	P	Polyproline II helix	trans	-76.7	135.8	-174.6	-59.6	-156.4	166.5	-175.8	0	112.1	N423	N423-K429 VanDerWaalsContact OD1-CA 3.3Å; N423-K429 WeakPolarHBondContact OD1-CA 3.46Å; N423-K429 WeakPolarHBondContact OD1-CB 3.36Å; N423-K429 VanDerWaalsContact OD1-CD 3.24Å; N423-K429 WeakPolarHBondContact OD1-CD 3.03Å; N423-K429 WeakPolarHBondContact OD1-CG 3.02Å
430	L	76.8	Confident	80.5	Confident	21 Å²	21	80.4 Å²	80.4	11%	0.11	38%	0.379	C	S	.	.	P	Polyproline II helix	trans	-75.6	125.9	171	-79.1	157.9	0	0	0	109.3	F178 L241 L244 T419 D434 Q435	F178-L430 HydrophobicContact CE2-CD1 4.49Å; F178-L430 HydrophobicContact CZ-CD1 4.44Å; L241-L430 HydrophobicContact CD1-CD2 4.48Å; L244-L430 HydrophobicContact CD1-CD1 4.12Å; L244-L430 HydrophobicContact CD1-CD2 4.34Å; T419-L430 HydrophobicContact CG2-CD1 4.12Å; L430-D434 HydrophobicContact CD2-CB 4.13Å; L430-Q435 HydrophobicContact CB-CG 4.35Å
431	T	82.4	Confident	80.2	Confident	75 Å²	75	72.6 Å²	72.6	46%	0.46	35%	0.346	S	S	.	.	P	Polyproline II helix	trans	-72.6	149.9	179.2	-40.3	0	0	0	0	110	K433 D434 Q435	T431-K433 HydrophobicContact CG2-CB 4.4Å; T431-K433 HydrophobicContact CG2-CG 4.46Å; T431-K433 PolarHBondContact O-N 2.94Å; T431-D434 WeakPolarHBondContact CA-OD2 3.4Å; T431-D434 WeakPolarHBondContact CB-OD2 3.3Å; T431-D434 PolarHBondContact N-OD2 2.71Å; T431-D434 WeakPolarHBondContact O-CA 3.35Å; T431-D434 WeakPolarHBondContact O-CB 3.19Å; T431-D434 PolarHBondContact O-N 3.48Å; T431-D434 PolarHBondContact OG1-OD2 3.38Å; T431-Q435 WeakPolarHBondContact O-CG 3.18Å; T431-Q435 PolarHBondContact O-N 3.22Å
432	K	84.1	Confident	79.9	Confident	177 Å²	177	68.3 Å²	68.3	77%	0.77	33%	0.325	S	S	*	.	H	α-helix	trans	-52.2	-28.9	172.4	-64.2	-170.7	178.4	-172.8	0	113.9	F436	K432-F436 PolarHBondContact O-N 3.31Å; K432-F436 VanDerWaalsContact O-N 3.13Å
433	K	84.2	Confident	80	Confident	80 Å²	80	68.1 Å²	68.1	35%	0.348	32%	0.324	S	S	.	.	H	α-helix	trans	-67.1	-49.1	172.1	-64.4	-175.7	-176.6	-179.5	0	112	T431 Q435 F436 I437 L494	T431-K433 HydrophobicContact CG2-CB 4.4Å; T431-K433 HydrophobicContact CG2-CG 4.46Å; T431-K433 PolarHBondContact O-N 2.94Å; K433-Q435 VanDerWaalsContact C-N 3.29Å; K433-Q435 PolarHBondContact O-N 2.99Å; K433-F436 PolarHBondContact O-N 3.08Å; K433-F436 VanDerWaalsContact O-N 3.16Å; K433-I437 WeakPolarHBondContact O-CG1 3.2Å; K433-I437 PolarHBondContact O-N 2.99Å; K433-L494 HydrophobicContact CB-CD2 4.28Å
434	D	83.8	Confident	80	Confident	38 Å²	38	66.3 Å²	66.3	20%	0.203	31%	0.314	C	S	.	.	H	α-helix	trans	-61.9	-41.4	179.4	-42.6	-25	0	0	0	110	L241 L430 T431 F436 I437 V438	L241-D434 HydrophobicContact CD1-CB 3.98Å; L430-D434 HydrophobicContact CD2-CB 4.13Å; T431-D434 WeakPolarHBondContact CA-OD2 3.4Å; T431-D434 WeakPolarHBondContact CB-OD2 3.3Å; T431-D434 PolarHBondContact N-OD2 2.71Å; T431-D434 WeakPolarHBondContact O-CA 3.35Å; T431-D434 WeakPolarHBondContact O-CB 3.19Å; T431-D434 PolarHBondContact O-N 3.48Å; T431-D434 PolarHBondContact OG1-OD2 3.38Å; D434-F436 PolarHBondContact O-N 3.46Å; D434-I437 PolarHBondContact O-N 3.14Å; D434-V438 VanDerWaalsContact O-CG2 3.28Å; D434-V438 WeakPolarHBondContact O-CG2 3.33Å; D434-V438 PolarHBondContact O-N 2.72Å
435	Q	88	Confident	79.9	Confident	26 Å²	26	58 Å²	58	12%	0.121	28%	0.279	C	S	.	.	H	α-helix	trans	-58.4	-46	173	-62.7	173.8	-12.2	0	0	111.9	T419 L430 T431 K433 V438 A439	T419-Q435 HydrophobicContact CG2-CG 3.89Å; T419-Q435 PolarHBondContact OG1-NE2 3.11Å; L430-Q435 HydrophobicContact CB-CG 4.35Å; T431-Q435 WeakPolarHBondContact O-CG 3.18Å; T431-Q435 PolarHBondContact O-N 3.22Å; K433-Q435 VanDerWaalsContact C-N 3.29Å; K433-Q435 PolarHBondContact O-N 2.99Å; Q435-V438 PolarHBondContact O-N 3.03Å; Q435-A439 WeakPolarHBondContact O-CB 3.3Å; Q435-A439 PolarHBondContact O-N 2.86Å
436	F	88.4	Confident	80.1	Confident	99 Å²	99	50.4 Å²	50.4	43%	0.434	25%	0.247	S	C	.	.	H	α-helix	trans	-65.2	-39.7	177.1	179.5	-98.4	0	0	0	112.1	K432 K433 D434 A439 Y440 L490 L494	K432-F436 PolarHBondContact O-N 3.31Å; K432-F436 VanDerWaalsContact O-N 3.13Å; K433-F436 PolarHBondContact O-N 3.08Å; K433-F436 VanDerWaalsContact O-N 3.16Å; D434-F436 PolarHBondContact O-N 3.46Å; F436-A439 PolarHBondContact O-N 3.24Å; F436-Y440 HydrophobicContact CZ-CD2 4.4Å; F436-Y440 WeakPolarHBondContact O-CB 3.5Å; F436-Y440 PolarHBondContact O-N 3.49Å; F436-L490 HydrophobicContact CE1-CD1 4.02Å; F436-L490 HydrophobicContact CE1-CD2 3.87Å; F436-L490 HydrophobicContact CE1-CG 4.18Å; F436-L490 HydrophobicContact CZ-CD2 4.39Å; F436-L494 HydrophobicContact CD1-CD2 3.81Å; F436-L494 HydrophobicContact CE1-CD2 4.45Å
437	I	85.5	Confident	80.9	Confident	14 Å²	14	49.7 Å²	49.7	7%	0.072	25%	0.246	C	C	.	.	H	α-helix	trans	-63.5	-43.3	175.6	-69.1	166.3	0	0	0	111.1	F232 L241 K433 D434 Y440 G441 V491 L494	F232-I437 HydrophobicContact CE1-CG2 3.86Å; F232-I437 HydrophobicContact CE2-CG2 4.38Å; F232-I437 HydrophobicContact CZ-CG2 3.38Å; L241-I437 HydrophobicContact CD2-CG2 3.94Å; K433-I437 WeakPolarHBondContact O-CG1 3.2Å; K433-I437 PolarHBondContact O-N 2.99Å; D434-I437 PolarHBondContact O-N 3.14Å; I437-Y440 PolarHBondContact O-N 3.01Å; I437-G441 PolarHBondContact O-N 3Å; I437-V491 HydrophobicContact CG2-CG2 4.47Å; I437-L494 HydrophobicContact CD1-CB 4.3Å; I437-L494 HydrophobicContact CD1-CD2 4Å; I437-L494 HydrophobicContact CG1-CD2 3.84Å
438	V	86	Confident	82.4	Confident	4 Å²	4	41.7 Å²	41.7	2%	0.024	21%	0.205	C	C	.	.	H	α-helix	trans	-68.1	-36.3	176.9	172.4	0	0	0	0	112.3	L241 L244 V245 R411 V415 D434 Q435	L241-V438 HydrophobicContact CD1-CG2 3.52Å; L241-V438 HydrophobicContact CG-CG2 4.46Å; L244-V438 HydrophobicContact CD2-CG1 4.33Å; L244-V438 HydrophobicContact CD2-CG2 4.32Å; V245-V438 HydrophobicContact CG2-CG2 3.83Å; R411-V438 PolarHBondContact NH2-O 3.08Å; V415-V438 HydrophobicContact CG1-CB 4.26Å; V415-V438 HydrophobicContact CG1-CG1 4.03Å; V415-V438 HydrophobicContact CG2-CG1 4.19Å; D434-V438 VanDerWaalsContact O-CG2 3.28Å; D434-V438 WeakPolarHBondContact O-CG2 3.33Å; D434-V438 PolarHBondContact O-N 2.72Å; Q435-V438 PolarHBondContact O-N 3.03Å
439	A	88.5	Confident	83.4	Confident	9 Å²	9	37.8 Å²	37.8	7%	0.074	18%	0.181	C	C	.	.	H	α-helix	trans	-67.4	-44	174.2	0	0	0	0	0	111.5	R411 V412 V415 Q435 F436	R411-A439 WeakPolarHBondContact CG-O 3.38Å; V412-A439 HydrophobicContact CG2-CB 4.41Å; V415-A439 HydrophobicContact CB-CB 4.1Å; V415-A439 HydrophobicContact CG1-CB 4.21Å; V415-A439 HydrophobicContact CG2-CB 4.29Å; Q435-A439 WeakPolarHBondContact O-CB 3.3Å; Q435-A439 PolarHBondContact O-N 2.86Å; F436-A439 PolarHBondContact O-N 3.24Å
440	Y	88.6	Confident	83.8	Confident	56 Å²	56	31.2 Å²	31.2	22%	0.22	15%	0.152	C	C	.	.	H	α-helix	trans	-73.2	-35.6	-179	-158.8	-89.8	0	0	0	113.2	F436 I437 G442 Q483 T486 I487 L490	F436-Y440 HydrophobicContact CZ-CD2 4.4Å; F436-Y440 WeakPolarHBondContact O-CB 3.5Å; F436-Y440 PolarHBondContact O-N 3.49Å; I437-Y440 PolarHBondContact O-N 3.01Å; Y440-G442 PolarHBondContact O-N 3.44Å; Y440-Q483 HydrophobicContact CE1-CB 3.86Å; Y440-Q483 HydrophobicContact CE1-CG 4.23Å; Y440-Q483 PolarHBondContact O-NE2 3.29Å; Y440-T486 WeakPolarHBondContact CE1-OG1 3.37Å; Y440-T486 PolarHBondContact OH-OG1 3.03Å; Y440-I487 HydrophobicContact CD1-CD1 3.87Å; Y440-L490 HydrophobicContact CD1-CD2 3.42Å; Y440-L490 VanDerWaalsContact CD1-CD2 3.42Å; Y440-L490 HydrophobicContact CD2-CD2 3.84Å; Y440-L490 HydrophobicContact CE1-CD2 3.64Å; Y440-L490 HydrophobicContact CE2-CD2 4.05Å; Y440-L490 HydrophobicContact CG-CD2 3.52Å
441	G	80.8	Confident	84.1	Confident	2 Å²	2	30.2 Å²	30.2	2%	0.021	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.9	9.5	-179.7	0	0	0	0	0	115.5	V228 I437 L443	V228-G441 WeakPolarHBondContact CG2-O 3.5Å; I437-G441 PolarHBondContact O-N 3Å; G441-L443 PolarHBondContact O-N 3.02Å
442	G	80.3	Confident	84.1	Confident	5 Å²	5	26.7 Å²	26.7	5%	0.052	13%	0.126	C	C	.	.			trans	-85.9	68.4	176.6	0	0	0	0	0	112.6	Y440	Y440-G442 PolarHBondContact O-N 3.44Å
443	L	85	Confident	83.9	Confident	8 Å²	8	19.6 Å²	19.6	4%	0.042	9%	0.094	C	C	.	.	B	Isolated β-bridge	trans	-70.1	155	178.3	-46.3	175.9	0	0	0	110.4	V223 D224 A227 V228 G441 Q483	V223-L443 CarbonylContact C-O 3.55Å; V223-L443 VanDerWaalsContact CA-O 3.3Å; V223-L443 WeakPolarHBondContact CA-O 3.46Å; D224-L443 PolarHBondContact N-O 2.96Å; D224-L443 WeakPolarHBondContact O-CB 3.33Å; A227-L443 HydrophobicContact CB-CD1 3.79Å; V228-L443 HydrophobicContact CG2-CD1 3.77Å; V228-L443 HydrophobicContact CG2-CG 3.94Å; G441-L443 PolarHBondContact O-N 3.02Å; L443-Q483 HydrophobicContact CD2-CB 3.5Å
444	R	85	Confident	83.6	Confident	6 Å²	6	18.3 Å²	18.3	2%	0.023	9%	0.091	C	C	.	.	P	Polyproline II helix	trans	-90	132.2	176.4	-62.7	-51.6	-173.9	-179.8	4.6	111.3	I220 S221 A222 C407 V475 I476 T479	I220-R444 WeakPolarHBondContact O-CD 3.26Å; I220-R444 PolarHBondContact O-NE 2.73Å; I220-R444 VanDerWaalsContact O-NE 3.12Å; I220-R444 PolarHBondContact O-NH1 2.91Å; I220-R444 PolarHBondContact O-NH2 3.4Å; S221-R444 PolarHBondContact O-NH1 3.28Å; A222-R444 WeakPolarHBondContact O-CD 3.41Å; A222-R444 PolarHBondContact O-NH1 3.36Å; C407-R444 PolarHBondContact SG-NE 2.94Å; C407-R444 PolarHBondContact SG-NH2 2.76Å; R444-V475 HydrophobicContact CG-CG1 3.77Å; R444-I476 HydrophobicContact CB-CG1 3.89Å; R444-T479 HydrophobicContact CB-CG2 4.46Å; R444-T479 HydrophobicContact CG-CG2 3.98Å; R444-T479 PolarHBondContact N-OG1 3.03Å; R444-T479 VanDerWaalsContact N-OG1 3.12Å
445	G	76.5	Confident	83.1	Confident	3 Å²	3	17.5 Å²	17.5	3%	0.031	9%	0.087	C	C	.	.	P	Polyproline II helix	trans	-91.7	168.5	-172.6	0	0	0	0	0	115.1	I447 A448	G445-I447 PolarHBondContact O-N 3.16Å; G445-A448 WeakPolarHBondContact O-CB 3.31Å; G445-A448 PolarHBondContact O-N 3.49Å
446	A	77.6	Confident	81.6	Confident	9 Å²	9	20.7 Å²	20.7	7%	0.074	10%	0.101	C	C	.	.	H	α-helix	trans	-72.2	-13.7	176.7	0	0	0	0	0	114.6	I380 F381 A448 F449 S450	I380-A446 HydrophobicContact CG2-CB 3.08Å; F381-A446 HydrophobicContact CE1-CB 4.49Å; A446-A448 VanDerWaalsContact C-N 3.32Å; A446-F449 WeakPolarHBondContact O-CB 3.38Å; A446-F449 PolarHBondContact O-N 3.45Å; A446-S450 PolarHBondContact O-N 2.89Å
447	I	85.6	Confident	79.9	Confident	20 Å²	20	22.7 Å²	22.7	10%	0.103	11%	0.112	C	C	.	.	H	α-helix	trans	-64.1	-39.3	171.1	-67.8	170.6	0	0	0	110.5	F147 L152 D253 V257 G445 F449 S450 L451	F147-I447 HydrophobicContact CE1-CG1 4.11Å; F147-I447 HydrophobicContact CZ-CB 4.46Å; F147-I447 HydrophobicContact CZ-CG1 3.8Å; L152-I447 HydrophobicContact CD1-CD1 3.98Å; L152-I447 HydrophobicContact CD1-CG1 4.01Å; D253-I447 HydrophobicContact CB-CD1 3.67Å; D253-I447 VanDerWaalsContact CG-CD1 3.44Å; V257-I447 HydrophobicContact CG2-CG2 4.17Å; G445-I447 PolarHBondContact O-N 3.16Å; I447-F449 VanDerWaalsContact C-N 3.29Å; I447-F449 PolarHBondContact O-N 2.93Å; I447-S450 PolarHBondContact O-N 3.42Å; I447-L451 HydrophobicContact CG2-CD1 3.96Å; I447-L451 HydrophobicContact CG2-CG 4.39Å; I447-L451 WeakPolarHBondContact O-CG 3.3Å; I447-L451 PolarHBondContact O-N 2.92Å
448	A	86.6	Confident	78.1	Confident	2 Å²	2	27.1 Å²	27.1	2%	0.017	14%	0.136	C	C	.	.	H	α-helix	trans	-60.8	-39	173.7	0	0	0	0	0	112	I219 A222 G445 A446 G452 I472 I476	I219-A448 HydrophobicContact CG2-CB 4.1Å; I219-A448 WeakPolarHBondContact CG2-O 3.24Å; I219-A448 WeakPolarHBondContact O-CB 3.22Å; A222-A448 HydrophobicContact CB-CB 4.46Å; G445-A448 WeakPolarHBondContact O-CB 3.31Å; G445-A448 PolarHBondContact O-N 3.49Å; A446-A448 VanDerWaalsContact C-N 3.32Å; A448-G452 PolarHBondContact O-N 3.13Å; A448-I472 HydrophobicContact CB-CG2 4.4Å; A448-I476 HydrophobicContact CB-CD1 4.44Å
449	F	84.1	Confident	76	Confident	1 Å²	1	34.5 Å²	34.5	0%	0.004	17%	0.17	C	C	.	.	H	α-helix	trans	-64	-47.4	174.8	165.9	-97.2	0	0	0	112.3	M142 L384 A446 I447 G452 Y453 I473 I476	M142-F449 HydrophobicContact CE-CD1 4.15Å; M142-F449 HydrophobicContact CE-CE1 3.75Å; L384-F449 HydrophobicContact CB-CD1 4.49Å; L384-F449 HydrophobicContact CB-CE1 4.45Å; L384-F449 HydrophobicContact CD1-CB 4.05Å; L384-F449 HydrophobicContact CD1-CD1 4.25Å; L384-F449 HydrophobicContact CD1-CD2 3.29Å; L384-F449 HydrophobicContact CD1-CE2 3.67Å; L384-F449 HydrophobicContact CD1-CG 3.62Å; L384-F449 HydrophobicContact CD1-CZ 4.34Å; A446-F449 WeakPolarHBondContact O-CB 3.38Å; A446-F449 PolarHBondContact O-N 3.45Å; I447-F449 VanDerWaalsContact C-N 3.29Å; I447-F449 PolarHBondContact O-N 2.93Å; F449-G452 PolarHBondContact O-N 2.92Å; F449-Y453 HydrophobicContact CD2-CD2 4.28Å; F449-Y453 HydrophobicContact CD2-CE2 4.1Å; F449-Y453 HydrophobicContact CE1-CD2 4.39Å; F449-Y453 HydrophobicContact CE1-CE2 4.43Å; F449-Y453 AromaticContact CE2-CD2 3.89Å; F449-Y453 HydrophobicContact CE2-CD2 3.89Å; F449-Y453 AromaticContact CE2-CE2 3.36Å; F449-Y453 HydrophobicContact CE2-CE2 3.36Å; F449-Y453 AromaticContact CZ-CD2 3.9Å; F449-Y453 HydrophobicContact CZ-CD2 3.9Å; F449-Y453 AromaticContact CZ-CE2 3.53Å; F449-Y453 HydrophobicContact CZ-CE2 3.53Å; F449-Y453 PolarHBondContact O-N 2.9Å; F449-I473 HydrophobicContact CD2-CG1 4.14Å; F449-I473 HydrophobicContact CE2-CD1 4.36Å; F449-I473 HydrophobicContact CE2-CG1 4.38Å; F449-I476 HydrophobicContact CB-CD1 3.74Å
450	S	82.8	Confident	74.1	Confident	0 Å²	0	38 Å²	38	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-63.1	-44.8	179.9	-172.2	0	0	0	0	112.6	F147 A446 I447 G452 Y453 L454	F147-S450 WeakPolarHBondContact CB-OG 3.13Å; F147-S450 VanDerWaalsContact CD1-CB 3.44Å; F147-S450 WeakPolarHBondContact CD1-OG 3.18Å; F147-S450 VanDerWaalsContact CE1-CB 3.44Å; F147-S450 WeakPolarHBondContact CG-OG 3.46Å; A446-S450 PolarHBondContact O-N 2.89Å; I447-S450 PolarHBondContact O-N 3.42Å; S450-G452 VanDerWaalsContact C-N 3.31Å; S450-G452 PolarHBondContact O-N 3.13Å; S450-Y453 PolarHBondContact O-N 3.48Å; S450-Y453 VanDerWaalsContact O-N 3.1Å; S450-L454 PolarHBondContact O-N 3.18Å
451	L	82.6	Confident	72.6	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-62.8	-36.4	173.6	-68.2	170.5	0	0	0	112	F148 I219 T256 V257 Y260 I447 Y453 L454 I455	F148-L451 HydrophobicContact CE1-CD2 4.5Å; F148-L451 HydrophobicContact CE2-CD2 4.19Å; F148-L451 HydrophobicContact CZ-CD2 3.57Å; F148-L451 HydrophobicContact CZ-CG 3.98Å; I219-L451 HydrophobicContact CD1-CB 4.26Å; I219-L451 HydrophobicContact CG1-CB 3.88Å; I219-L451 HydrophobicContact CG2-CB 4.05Å; T256-L451 HydrophobicContact CG2-CD1 3.91Å; V257-L451 HydrophobicContact CG2-CD1 4.15Å; V257-L451 HydrophobicContact CG2-CD2 4.37Å; Y260-L451 HydrophobicContact CD1-CD2 3.84Å; Y260-L451 HydrophobicContact CD2-CB 4.31Å; Y260-L451 HydrophobicContact CD2-CD2 4.1Å; Y260-L451 HydrophobicContact CE1-CD2 4.35Å; Y260-L451 HydrophobicContact CG-CD2 3.75Å; I447-L451 HydrophobicContact CG2-CD1 3.96Å; I447-L451 HydrophobicContact CG2-CG 4.39Å; I447-L451 WeakPolarHBondContact O-CG 3.3Å; I447-L451 PolarHBondContact O-N 2.92Å; L451-Y453 PolarHBondContact O-N 2.87Å; L451-L454 HydrophobicContact CD2-CD2 4.3Å; L451-L454 WeakPolarHBondContact O-CB 3.2Å; L451-L454 PolarHBondContact O-N 3.01Å; L451-I455 PolarHBondContact O-N 3.41Å
452	G	81.9	Confident	71.6	Confident	1 Å²	1	42 Å²	42	1%	0.01	23%	0.23	C	C	.	.	H	α-helix	trans	-60.1	-29.4	172.8	0	0	0	0	0	113.9	A448 F449 S450	A448-G452 PolarHBondContact O-N 3.13Å; F449-G452 PolarHBondContact O-N 2.92Å; S450-G452 VanDerWaalsContact C-N 3.31Å; S450-G452 PolarHBondContact O-N 3.13Å
453	Y	79.8	Confident	70.9	Confident	28 Å²	28	47.4 Å²	47.4	11%	0.11	26%	0.258	C	S	.	.	H	α-helix	trans	-81.3	-22	171.8	-91.7	-95.7	0	0	0	113.8	V141 F449 S450 L451 R465 L469	V141-Y453 HydrophobicContact CG1-CD1 4.43Å; V141-Y453 HydrophobicContact CG1-CE1 3.93Å; F449-Y453 HydrophobicContact CD2-CD2 4.28Å; F449-Y453 HydrophobicContact CD2-CE2 4.1Å; F449-Y453 HydrophobicContact CE1-CD2 4.39Å; F449-Y453 HydrophobicContact CE1-CE2 4.43Å; F449-Y453 AromaticContact CE2-CD2 3.89Å; F449-Y453 HydrophobicContact CE2-CD2 3.89Å; F449-Y453 AromaticContact CE2-CE2 3.36Å; F449-Y453 HydrophobicContact CE2-CE2 3.36Å; F449-Y453 AromaticContact CZ-CD2 3.9Å; F449-Y453 HydrophobicContact CZ-CD2 3.9Å; F449-Y453 AromaticContact CZ-CE2 3.53Å; F449-Y453 HydrophobicContact CZ-CE2 3.53Å; F449-Y453 PolarHBondContact O-N 2.9Å; S450-Y453 PolarHBondContact O-N 3.48Å; S450-Y453 VanDerWaalsContact O-N 3.1Å; L451-Y453 PolarHBondContact O-N 2.87Å; Y453-R465 VanDerWaalsContact O-CZ 3.24Å; Y453-R465 PolarHBondContact O-NH1 3.17Å; Y453-R465 PolarHBondContact O-NH2 2.92Å; Y453-L469 HydrophobicContact CD2-CD1 3.58Å; Y453-L469 HydrophobicContact CD2-CD2 4.38Å; Y453-L469 HydrophobicContact CE1-CD2 4.33Å; Y453-L469 HydrophobicContact CE2-CD1 3.48Å; Y453-L469 VanDerWaalsContact CE2-CD1 3.48Å; Y453-L469 HydrophobicContact CE2-CD2 3.75Å; Y453-L469 HydrophobicContact CE2-CG 4.16Å; Y453-L469 HydrophobicContact CG-CD1 4.47Å
454	L	77.3	Confident	70.2	Confident	53 Å²	53	48.6 Å²	48.6	28%	0.277	27%	0.265	S	S	.	.	H	α-helix	trans	-72.5	-31.1	179	-163.8	48	0	0	0	113	T144 F148 Y260 S450 L451 H456	T144-L454 HydrophobicContact CG2-CB 3.92Å; T144-L454 HydrophobicContact CG2-CD1 3.84Å; T144-L454 HydrophobicContact CG2-CD2 4.28Å; T144-L454 HydrophobicContact CG2-CG 4.22Å; F148-L454 HydrophobicContact CE2-CD2 4.34Å; Y260-L454 HydrophobicContact CD1-CD2 4.32Å; Y260-L454 HydrophobicContact CE1-CB 4.42Å; Y260-L454 HydrophobicContact CE1-CD2 3.54Å; Y260-L454 HydrophobicContact CE1-CG 3.96Å; Y260-L454 WeakPolarHBondContact OH-CG 3.42Å; S450-L454 PolarHBondContact O-N 3.18Å; L451-L454 HydrophobicContact CD2-CD2 4.3Å; L451-L454 WeakPolarHBondContact O-CB 3.2Å; L451-L454 PolarHBondContact O-N 3.01Å; L454-H456 PolarHBondContact O-N 3.35Å
455	I	73.5	Confident	69.8	Low	21 Å²	21	50.1 Å²	50.1	11%	0.108	27%	0.271	C	S	.	.	S	Bend	trans	-44.4	121.4	-176.4	-53.7	-178.2	0	0	0	111.4	L215 I219 Y260 L451 R465 F468	L215-I455 HydrophobicContact CD2-CD1 4.03Å; L215-I455 HydrophobicContact CD2-CG1 4.02Å; I219-I455 HydrophobicContact CD1-CD1 3.59Å; I219-I455 HydrophobicContact CD1-CG1 3.77Å; Y260-I455 HydrophobicContact CE2-CG1 4.4Å; Y260-I455 PolarHBondContact OH-N 3.36Å; L451-I455 PolarHBondContact O-N 3.41Å; I455-R465 PolarHBondContact O-NH1 3.34Å; I455-F468 HydrophobicContact CD1-CD2 4.2Å
456	H	58.1	Low	70	Confident	94 Å²	94	50.3 Å²	50.3	44%	0.435	27%	0.273	S	S	.	.			trans	-49.7	143	-171.5	-88.6	75.7	0	0	0	114.9	E264 H268 L454 D458	E264-H456 IonicContact OE1-CE1 2.95Å; E264-H456 PolarHBondContact OE1-CE1 3.5Å; E264-H456 VanDerWaalsContact OE1-CE1 3.25Å; E264-H456 IonicContact OE1-ND1 2.61Å; E264-H456 PolarHBondContact OE1-ND1 3.21Å; H268-H456 AromaticContact NE2-CE1 3.91Å; H268-H456 AromaticContact NE2-NE2 4Å; L454-H456 PolarHBondContact O-N 3.35Å; H456-D458 PolarHBondContact O-N 2.89Å
457	Q	52	Low	70.2	Confident	141 Å²	141	50.7 Å²	50.7	66%	0.659	27%	0.274	S	S	*	.			trans	-96.9	61.2	-176.5	-67.5	-174.5	-18.1	0	0	112.6
458	D	48.1	Very low	70.2	Confident	106 Å²	106	50 Å²	50	57%	0.567	27%	0.27	S	S	*	.			trans	-73.9	141.4	168.4	-76.9	-37	0	0	0	111	H456 G460 S461 K462	H456-D458 PolarHBondContact O-N 2.89Å; D458-G460 PolarHBondContact O-N 3.44Å; D458-G460 VanDerWaalsContact O-N 3.12Å; D458-S461 PolarHBondContact O-N 3.03Å; D458-S461 PolarHBondContact O-OG 3.5Å; D458-S461 VanDerWaalsContact O-OG 3.07Å; D458-K462 PolarHBondContact O-N 3.12Å
459	E	42	Very low	70.1	Confident	159 Å²	159	50.1 Å²	50.1	74%	0.743	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.3	-26.5	-165.8	-61	-130.6	105.8	0	0	113.9	K462	E459-K462 IonicContact OE1-NZ 2.84Å; E459-K462 PolarHBondContact OE1-NZ 3.19Å
460	G	47.8	Very low	70.3	Confident	83 Å²	83	50.1 Å²	50.1	86%	0.856	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.1	-9.6	174.5	0	0	0	0	0	115.6	D458	D458-G460 PolarHBondContact O-N 3.44Å; D458-G460 VanDerWaalsContact O-N 3.12Å
461	S	56.5	Low	70.6	Confident	41 Å²	41	50.1 Å²	50.1	29%	0.287	27%	0.27	S	S	.	.	T	Hydrogen-bonded Turn	trans	-106.5	-0.1	-176.6	67.2	0	0	0	0	114.1	D458 D463 T464 R465	D458-S461 PolarHBondContact O-N 3.03Å; D458-S461 PolarHBondContact O-OG 3.5Å; D458-S461 VanDerWaalsContact O-OG 3.07Å; S461-D463 VanDerWaalsContact C-N 3.3Å; S461-D463 PolarHBondContact O-N 3.19Å; S461-T464 WeakPolarHBondContact O-CB 3.13Å; S461-T464 PolarHBondContact O-N 2.84Å; S461-T464 VanDerWaalsContact O-N 3.11Å; S461-R465 PolarHBondContact O-N 2.65Å
462	K	60.3	Low	70.9	Confident	102 Å²	102	50.2 Å²	50.2	44%	0.443	27%	0.271	S	S	.	.	H	α-helix	trans	-51.9	-41.8	-179.4	-71.4	172.2	179.7	163.5	0	113.4	D458 E459 R465 G466	D458-K462 PolarHBondContact O-N 3.12Å; E459-K462 IonicContact OE1-NZ 2.84Å; E459-K462 PolarHBondContact OE1-NZ 3.19Å; K462-R465 PolarHBondContact O-N 3.32Å; K462-G466 PolarHBondContact O-N 3.32Å
463	D	65.5	Low	71.2	Confident	118 Å²	118	50.4 Å²	50.4	63%	0.631	27%	0.272	S	S	*	.	H	α-helix	trans	-68.8	-41.3	178.8	-75.1	-17.9	0	0	0	112.7	S461 G466 M467	S461-D463 VanDerWaalsContact C-N 3.3Å; S461-D463 PolarHBondContact O-N 3.19Å; D463-G466 PolarHBondContact O-N 3.34Å; D463-G466 VanDerWaalsContact O-N 3.16Å; D463-M467 PolarHBondContact O-N 3.46Å
464	T	71.2	Confident	71.7	Confident	32 Å²	32	50.6 Å²	50.6	20%	0.196	28%	0.276	C	S	.	.	H	α-helix	trans	-62.3	-42.8	175.4	-55.5	0	0	0	0	111.3	V208 S461 G466 M467 F468	V208-T464 HydrophobicContact CG1-CG2 4.2Å; V208-T464 HydrophobicContact CG2-CG2 3.82Å; S461-T464 WeakPolarHBondContact O-CB 3.13Å; S461-T464 PolarHBondContact O-N 2.84Å; S461-T464 VanDerWaalsContact O-N 3.11Å; T464-G466 VanDerWaalsContact C-N 3.33Å; T464-G466 PolarHBondContact O-N 2.79Å; T464-M467 PolarHBondContact O-N 3.45Å; T464-F468 HydrophobicContact CG2-CD1 4.45Å; T464-F468 HydrophobicContact CG2-CD2 4.35Å; T464-F468 HydrophobicContact CG2-CE1 4.02Å; T464-F468 HydrophobicContact CG2-CE2 3.91Å; T464-F468 HydrophobicContact CG2-CZ 3.74Å; T464-F468 WeakPolarHBondContact O-CG 3.33Å; T464-F468 PolarHBondContact O-N 2.8Å
465	R	76.9	Confident	72.3	Confident	39 Å²	39	48.3 Å²	48.3	15%	0.147	26%	0.264	C	S	.	.	H	α-helix	trans	-59.3	-43	172.5	176.7	-177.6	157.9	131.6	7.4	111.4	Y453 I455 S461 K462 F468 L469	Y453-R465 VanDerWaalsContact O-CZ 3.24Å; Y453-R465 PolarHBondContact O-NH1 3.17Å; Y453-R465 PolarHBondContact O-NH2 2.92Å; I455-R465 PolarHBondContact O-NH1 3.34Å; S461-R465 PolarHBondContact O-N 2.65Å; K462-R465 PolarHBondContact O-N 3.32Å; R465-F468 PolarHBondContact O-N 3.23Å; R465-L469 WeakPolarHBondContact O-CB 3.36Å; R465-L469 PolarHBondContact O-N 3.19Å
466	G	79.6	Confident	73.1	Confident	7 Å²	7	47.4 Å²	47.4	7%	0.072	26%	0.259	C	S	.	.	H	α-helix	trans	-59.2	-45	175.9	0	0	0	0	0	113	K462 D463 T464 T470	K462-G466 PolarHBondContact O-N 3.32Å; D463-G466 PolarHBondContact O-N 3.34Å; D463-G466 VanDerWaalsContact O-N 3.16Å; T464-G466 VanDerWaalsContact C-N 3.33Å; T464-G466 PolarHBondContact O-N 2.79Å; G466-T470 WeakPolarHBondContact O-CB 3.31Å; G466-T470 PolarHBondContact O-N 2.99Å; G466-T470 PolarHBondContact O-OG1 2.86Å
467	M	81.7	Confident	74.6	Confident	17 Å²	17	44.8 Å²	44.8	8%	0.084	25%	0.247	C	C	.	.	H	α-helix	trans	-62.7	-47.6	175.3	-67.3	-167.8	-65.7	0	0	112.2	A205 N394 N396 D463 T464 L469 T470 A471	A205-M467 HydrophobicContact CB-CE 4.36Å; N394-M467 HydrophobicContact CB-CG 4.1Å; N396-M467 HydrophobicContact CB-CG 4.42Å; N396-M467 HydrophobicContact CB-SD 3.95Å; D463-M467 PolarHBondContact O-N 3.46Å; T464-M467 PolarHBondContact O-N 3.45Å; M467-L469 PolarHBondContact O-N 3.04Å; M467-T470 PolarHBondContact O-N 3.26Å; M467-A471 WeakPolarHBondContact O-CB 3.42Å; M467-A471 PolarHBondContact O-N 3.17Å
468	F	85.4	Confident	76.4	Confident	5 Å²	5	41.1 Å²	41.1	2%	0.022	23%	0.229	C	C	.	.	H	α-helix	trans	-61.2	-44.8	178.9	-72.7	-4.1	0	0	0	112	V208 F216 F399 I455 T464 R465 A471 I472	V208-F468 HydrophobicContact CG1-CE1 4.28Å; V208-F468 HydrophobicContact CG1-CZ 3.73Å; F216-F468 HydrophobicContact CB-CD2 4.19Å; F216-F468 HydrophobicContact CB-CE1 4.47Å; F216-F468 HydrophobicContact CB-CE2 4.01Å; F216-F468 HydrophobicContact CB-CG 4.49Å; F216-F468 HydrophobicContact CB-CZ 4.15Å; F216-F468 HydrophobicContact CD2-CB 3.74Å; F216-F468 AromaticContact CD2-CD1 3.81Å; F216-F468 HydrophobicContact CD2-CD1 3.81Å; F216-F468 HydrophobicContact CD2-CD2 4.04Å; F216-F468 HydrophobicContact CD2-CE1 4.4Å; F216-F468 AromaticContact CD2-CG 3.6Å; F216-F468 HydrophobicContact CD2-CG 3.6Å; F216-F468 HydrophobicContact CE2-CB 3.87Å; F216-F468 HydrophobicContact CE2-CD1 4.02Å; F216-F468 HydrophobicContact CE2-CG 4.03Å; F216-F468 HydrophobicContact CG-CD1 4.19Å; F216-F468 HydrophobicContact CG-CD2 4.43Å; F216-F468 HydrophobicContact CG-CE1 4.33Å; F216-F468 HydrophobicContact CG-CG 4.24Å; F216-F468 HydrophobicContact CG-CZ 4.49Å; F399-F468 AromaticContact CE1-CD1 3.85Å; F399-F468 HydrophobicContact CE1-CD1 3.85Å; F399-F468 HydrophobicContact CE1-CE1 4.26Å; F399-F468 HydrophobicContact CE2-CE1 4.26Å; F399-F468 AromaticContact CZ-CD1 3.66Å; F399-F468 HydrophobicContact CZ-CD1 3.66Å; F399-F468 AromaticContact CZ-CE1 3.6Å; F399-F468 HydrophobicContact CZ-CE1 3.6Å; I455-F468 HydrophobicContact CD1-CD2 4.2Å; T464-F468 HydrophobicContact CG2-CD1 4.45Å; T464-F468 HydrophobicContact CG2-CD2 4.35Å; T464-F468 HydrophobicContact CG2-CE1 4.02Å; T464-F468 HydrophobicContact CG2-CE2 3.91Å; T464-F468 HydrophobicContact CG2-CZ 3.74Å; T464-F468 WeakPolarHBondContact O-CG 3.33Å; T464-F468 PolarHBondContact O-N 2.8Å; R465-F468 PolarHBondContact O-N 3.23Å; F468-A471 PolarHBondContact O-N 2.92Å; F468-I472 WeakPolarHBondContact O-CD1 3.2Å; F468-I472 WeakPolarHBondContact O-CG1 3.45Å; F468-I472 PolarHBondContact O-N 2.9Å
469	L	85.6	Confident	78.4	Confident	5 Å²	5	36.2 Å²	36.2	3%	0.026	20%	0.202	C	C	.	.	H	α-helix	trans	-64.2	-44.2	179	-173.8	67.8	0	0	0	111.6	Y453 R465 M467 A471 I472 I473	Y453-L469 HydrophobicContact CD2-CD1 3.58Å; Y453-L469 HydrophobicContact CD2-CD2 4.38Å; Y453-L469 HydrophobicContact CE1-CD2 4.33Å; Y453-L469 HydrophobicContact CE2-CD1 3.48Å; Y453-L469 VanDerWaalsContact CE2-CD1 3.48Å; Y453-L469 HydrophobicContact CE2-CD2 3.75Å; Y453-L469 HydrophobicContact CE2-CG 4.16Å; Y453-L469 HydrophobicContact CG-CD1 4.47Å; R465-L469 WeakPolarHBondContact O-CB 3.36Å; R465-L469 PolarHBondContact O-N 3.19Å; M467-L469 PolarHBondContact O-N 3.04Å; L469-A471 VanDerWaalsContact C-N 3.28Å; L469-A471 PolarHBondContact O-N 3.34Å; L469-I472 PolarHBondContact O-N 3.48Å; L469-I473 HydrophobicContact CD1-CD1 4.27Å; L469-I473 HydrophobicContact CG-CD1 3.94Å; L469-I473 WeakPolarHBondContact O-CB 3.4Å; L469-I473 VanDerWaalsContact O-CG1 3.31Å; L469-I473 WeakPolarHBondContact O-CG1 3.45Å; L469-I473 PolarHBondContact O-N 3.11Å
470	T	87.5	Confident	80.5	Confident	1 Å²	1	29.1 Å²	29.1	1%	0.006	17%	0.17	C	C	.	.	H	α-helix	trans	-59.4	-40.4	175.8	-51.8	0	0	0	0	111.1	H393 N394 W395 G466 M467 T474	H393-T470 WeakPolarHBondContact CA-OG1 3.45Å; H393-T470 HydrophobicContact CB-CG2 4.32Å; N394-T470 PolarHBondContact N-OG1 3.47Å; W395-T470 HydrophobicContact CD2-CG2 4.05Å; W395-T470 HydrophobicContact CG-CG2 4.16Å; W395-T470 HydrophobicContact CZ2-CG2 4.31Å; G466-T470 WeakPolarHBondContact O-CB 3.31Å; G466-T470 PolarHBondContact O-N 2.99Å; G466-T470 PolarHBondContact O-OG1 2.86Å; M467-T470 PolarHBondContact O-N 3.26Å; T470-T474 WeakPolarHBondContact O-CB 3.38Å; T470-T474 PolarHBondContact O-N 2.89Å; T470-T474 PolarHBondContact O-OG1 2.84Å
471	A	89	Confident	82.4	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-68.4	-46.4	176.5	0	0	0	0	0	113	F216 F399 V400 M467 F468 L469 I473 T474 V475	F216-A471 HydrophobicContact CE2-CB 4.14Å; F216-A471 HydrophobicContact CZ-CB 3.83Å; F399-A471 HydrophobicContact CD1-CB 4Å; F399-A471 HydrophobicContact CE1-CB 3.81Å; V400-A471 HydrophobicContact CG2-CB 4.06Å; M467-A471 WeakPolarHBondContact O-CB 3.42Å; M467-A471 PolarHBondContact O-N 3.17Å; F468-A471 PolarHBondContact O-N 2.92Å; L469-A471 VanDerWaalsContact C-N 3.28Å; L469-A471 PolarHBondContact O-N 3.34Å; A471-I473 PolarHBondContact O-N 3.32Å; A471-T474 PolarHBondContact O-N 2.95Å; A471-V475 WeakPolarHBondContact O-CG2 3.41Å; A471-V475 PolarHBondContact O-N 3.41Å
472	I	89.6	Confident	84	Confident	2 Å²	2	28.8 Å²	28.8	1%	0.01	15%	0.145	C	C	.	.	H	α-helix	trans	-58.4	-49.2	176.6	-71	157.9	0	0	0	110.4	F216 I219 I220 A448 F468 L469 T474 V475 I476	F216-I472 HydrophobicContact CD2-CD1 4.21Å; F216-I472 HydrophobicContact CD2-CG1 4.34Å; F216-I472 HydrophobicContact CE2-CD1 4.15Å; F216-I472 HydrophobicContact CE2-CG1 3.86Å; I219-I472 HydrophobicContact CG2-CD1 3.7Å; I219-I472 HydrophobicContact CG2-CG1 4.33Å; I220-I472 HydrophobicContact CD1-CG1 4.23Å; I220-I472 HydrophobicContact CG1-CG1 3.99Å; A448-I472 HydrophobicContact CB-CG2 4.4Å; F468-I472 WeakPolarHBondContact O-CD1 3.2Å; F468-I472 WeakPolarHBondContact O-CG1 3.45Å; F468-I472 PolarHBondContact O-N 2.9Å; L469-I472 PolarHBondContact O-N 3.48Å; I472-T474 PolarHBondContact O-N 2.81Å; I472-V475 PolarHBondContact O-N 2.86Å; I472-I476 HydrophobicContact CG2-CD1 3.71Å; I472-I476 HydrophobicContact CG2-CG1 4.47Å; I472-I476 VanDerWaalsContact O-CG1 3.31Å; I472-I476 WeakPolarHBondContact O-CG1 3.39Å; I472-I476 PolarHBondContact O-N 3.08Å
473	I	88.6	Confident	85.3	Confident	5 Å²	5	24.6 Å²	24.6	3%	0.026	13%	0.127	C	C	.	.	H	α-helix	trans	-58.3	-49.7	177.1	-69	171.3	0	0	0	109.8	T388 F449 L469 A471 V475 I476 F477	T388-I473 HydrophobicContact CG2-CG2 3.83Å; F449-I473 HydrophobicContact CD2-CG1 4.14Å; F449-I473 HydrophobicContact CE2-CD1 4.36Å; F449-I473 HydrophobicContact CE2-CG1 4.38Å; L469-I473 HydrophobicContact CD1-CD1 4.27Å; L469-I473 HydrophobicContact CG-CD1 3.94Å; L469-I473 WeakPolarHBondContact O-CB 3.4Å; L469-I473 VanDerWaalsContact O-CG1 3.31Å; L469-I473 WeakPolarHBondContact O-CG1 3.45Å; L469-I473 PolarHBondContact O-N 3.11Å; A471-I473 PolarHBondContact O-N 3.32Å; I473-V475 VanDerWaalsContact C-N 3.33Å; I473-V475 PolarHBondContact O-N 3.21Å; I473-I476 PolarHBondContact O-N 3.16Å; I473-F477 HydrophobicContact CG2-CD2 3.68Å; I473-F477 HydrophobicContact CG2-CE2 3.82Å; I473-F477 WeakPolarHBondContact O-CD2 3.43Å; I473-F477 PolarHBondContact O-N 3.37Å
474	T	89.5	Confident	86.3	Confident	32 Å²	32	19.1 Å²	19.1	20%	0.196	10%	0.099	C	C	.	.	H	α-helix	trans	-61.5	-38.9	-179.2	-55.4	0	0	0	0	112.7	V400 T470 A471 I472 F477 F478	V400-T474 HydrophobicContact CG1-CG2 3.56Å; T470-T474 WeakPolarHBondContact O-CB 3.38Å; T470-T474 PolarHBondContact O-N 2.89Å; T470-T474 PolarHBondContact O-OG1 2.84Å; A471-T474 PolarHBondContact O-N 2.95Å; I472-T474 PolarHBondContact O-N 2.81Å; T474-F477 PolarHBondContact O-N 3.46Å; T474-F478 WeakPolarHBondContact O-CB 3.25Å; T474-F478 PolarHBondContact O-N 3.04Å
475	V	90.6	Very high	86.9	Confident	4 Å²	4	21 Å²	21	2%	0.024	11%	0.106	C	C	.	.	H	α-helix	trans	-68	-41.6	175.6	173.4	0	0	0	0	111.2	T403 L404 R444 A471 I472 I473 F478 T479	T403-V475 HydrophobicContact CG2-CG2 3.92Å; L404-V475 HydrophobicContact CB-CG2 4.46Å; R444-V475 HydrophobicContact CG-CG1 3.77Å; A471-V475 WeakPolarHBondContact O-CG2 3.41Å; A471-V475 PolarHBondContact O-N 3.41Å; I472-V475 PolarHBondContact O-N 2.86Å; I473-V475 VanDerWaalsContact C-N 3.33Å; I473-V475 PolarHBondContact O-N 3.21Å; V475-F478 PolarHBondContact O-N 3.34Å; V475-T479 HydrophobicContact CG1-CG2 4.23Å; V475-T479 WeakPolarHBondContact O-CB 3.48Å; V475-T479 VanDerWaalsContact O-CG2 3.3Å; V475-T479 WeakPolarHBondContact O-CG2 3.39Å; V475-T479 PolarHBondContact O-N 2.98Å; V475-T479 PolarHBondContact O-OG1 3.2Å
476	I	89.9	Confident	87.5	Confident	2 Å²	2	21.6 Å²	21.6	1%	0.01	11%	0.114	C	C	.	.	H	α-helix	trans	-62	-47.1	175	-66.9	166.5	0	0	0	110.1	L384 R444 A448 F449 I472 I473 F478 T479 V480	L384-I476 HydrophobicContact CD2-CG2 3.8Å; R444-I476 HydrophobicContact CB-CG1 3.89Å; A448-I476 HydrophobicContact CB-CD1 4.44Å; F449-I476 HydrophobicContact CB-CD1 3.74Å; I472-I476 HydrophobicContact CG2-CD1 3.71Å; I472-I476 HydrophobicContact CG2-CG1 4.47Å; I472-I476 VanDerWaalsContact O-CG1 3.31Å; I472-I476 WeakPolarHBondContact O-CG1 3.39Å; I472-I476 PolarHBondContact O-N 3.08Å; I473-I476 PolarHBondContact O-N 3.16Å; I476-F478 PolarHBondContact O-N 3.36Å; I476-T479 PolarHBondContact O-N 3.34Å; I476-T479 PolarHBondContact O-OG1 3.42Å; I476-V480 HydrophobicContact CG2-CG2 4Å; I476-V480 VanDerWaalsContact O-CB 3.31Å; I476-V480 WeakPolarHBondContact O-CB 2.96Å; I476-V480 VanDerWaalsContact O-CG2 3.31Å; I476-V480 WeakPolarHBondContact O-CG2 3.38Å; I476-V480 PolarHBondContact O-N 3.03Å
477	F	88.8	Confident	87.8	Confident	40 Å²	40	21.3 Å²	21.3	18%	0.175	11%	0.111	C	C	.	.	H	α-helix	trans	-58.1	-46.8	174.9	-92.3	-90.8	0	0	0	112.4	I122 L126 T388 I473 T474 F481	I122-F477 HydrophobicContact CG2-CE1 3.55Å; I122-F477 HydrophobicContact CG2-CE2 4.08Å; I122-F477 HydrophobicContact CG2-CZ 3.3Å; L126-F477 HydrophobicContact CD1-CE1 3.64Å; L126-F477 HydrophobicContact CD1-CZ 3.79Å; L126-F477 HydrophobicContact CD2-CZ 4.11Å; L126-F477 HydrophobicContact CG-CE1 4.41Å; L126-F477 HydrophobicContact CG-CZ 4.07Å; T388-F477 HydrophobicContact CG2-CE2 3.84Å; T388-F477 HydrophobicContact CG2-CZ 4.14Å; T388-F477 WeakPolarHBondContact OG1-CE2 3.01Å; I473-F477 HydrophobicContact CG2-CD2 3.68Å; I473-F477 HydrophobicContact CG2-CE2 3.82Å; I473-F477 WeakPolarHBondContact O-CD2 3.43Å; I473-F477 PolarHBondContact O-N 3.37Å; T474-F477 PolarHBondContact O-N 3.46Å; F477-F481 AromaticContact CD1-CD2 3.69Å; F477-F481 HydrophobicContact CD1-CD2 3.69Å; F477-F481 AromaticContact CD1-CE2 3.41Å; F477-F481 HydrophobicContact CD1-CE2 3.41Å; F477-F481 VanDerWaalsContact CD1-CE2 3.41Å; F477-F481 HydrophobicContact CD1-CZ 4.4Å; F477-F481 HydrophobicContact CE1-CD2 4.28Å; F477-F481 AromaticContact CE1-CE2 3.53Å; F477-F481 HydrophobicContact CE1-CE2 3.53Å; F477-F481 HydrophobicContact CE1-CZ 4.22Å; F477-F481 HydrophobicContact CG-CD2 4.47Å; F477-F481 HydrophobicContact CG-CE2 4.43Å; F477-F481 WeakPolarHBondContact O-CB 3.24Å; F477-F481 WeakPolarHBondContact O-CD2 3.45Å; F477-F481 PolarHBondContact O-N 2.95Å
478	F	90.4	Very high	87.9	Confident	63 Å²	63	22.3 Å²	22.3	28%	0.276	11%	0.114	S	C	.	.	I	π-helix	trans	-62	-48.1	177.7	179.6	-93.7	0	0	0	112	L404 L408 T474 V475 I476 V482	L404-F478 HydrophobicContact CD1-CB 3.9Å; L404-F478 HydrophobicContact CD1-CD1 4.02Å; L404-F478 HydrophobicContact CD1-CD2 3.8Å; L404-F478 HydrophobicContact CD1-CE2 4.33Å; L404-F478 HydrophobicContact CD1-CG 3.62Å; L404-F478 HydrophobicContact CD2-CD1 4.27Å; L404-F478 HydrophobicContact CD2-CE1 4.09Å; L404-F478 HydrophobicContact CD2-CZ 4.22Å; L404-F478 HydrophobicContact CG-CD1 4.09Å; L404-F478 HydrophobicContact CG-CE1 4.43Å; L404-F478 HydrophobicContact CG-CG 4.21Å; L408-F478 HydrophobicContact CD1-CE1 3.94Å; L408-F478 HydrophobicContact CD1-CZ 4.37Å; L408-F478 HydrophobicContact CD2-CE1 4.3Å; T474-F478 WeakPolarHBondContact O-CB 3.25Å; T474-F478 PolarHBondContact O-N 3.04Å; V475-F478 PolarHBondContact O-N 3.34Å; I476-F478 PolarHBondContact O-N 3.36Å; F478-V482 HydrophobicContact CD2-CB 4.28Å; F478-V482 HydrophobicContact CD2-CG2 3.72Å; F478-V482 HydrophobicContact CE2-CB 4.14Å; F478-V482 HydrophobicContact CE2-CG1 4.27Å; F478-V482 HydrophobicContact CE2-CG2 3.83Å; F478-V482 HydrophobicContact CG-CG2 4.36Å; F478-V482 HydrophobicContact CZ-CB 4.34Å; F478-V482 HydrophobicContact CZ-CG1 4.3Å; F478-V482 WeakPolarHBondContact O-CA 3.45Å; F478-V482 WeakPolarHBondContact O-CB 3.35Å; F478-V482 WeakPolarHBondContact O-CG2 3.45Å; F478-V482 PolarHBondContact O-N 3.39Å
479	T	89.8	Confident	87.9	Confident	3 Å²	3	25.4 Å²	25.4	2%	0.018	14%	0.135	C	C	.	.	I	π-helix	trans	-67	-49	-178.9	59.8	0	0	0	0	111.6	R444 V475 I476 Q483 G484	R444-T479 HydrophobicContact CB-CG2 4.46Å; R444-T479 HydrophobicContact CG-CG2 3.98Å; R444-T479 PolarHBondContact N-OG1 3.03Å; R444-T479 VanDerWaalsContact N-OG1 3.12Å; V475-T479 HydrophobicContact CG1-CG2 4.23Å; V475-T479 WeakPolarHBondContact O-CB 3.48Å; V475-T479 VanDerWaalsContact O-CG2 3.3Å; V475-T479 WeakPolarHBondContact O-CG2 3.39Å; V475-T479 PolarHBondContact O-N 2.98Å; V475-T479 PolarHBondContact O-OG1 3.2Å; I476-T479 PolarHBondContact O-N 3.34Å; I476-T479 PolarHBondContact O-OG1 3.42Å; T479-Q483 VanDerWaalsContact CB-OE1 3.24Å; T479-Q483 CarbonylContact O-C 3.51Å; T479-Q483 WeakPolarHBondContact O-CA 3.46Å; T479-Q483 VanDerWaalsContact O-CB 3.26Å; T479-Q483 WeakPolarHBondContact O-CB 3Å; T479-Q483 PolarHBondContact O-N 3.25Å; T479-G484 PolarHBondContact O-N 3Å
480	V	86.7	Confident	87.9	Confident	10 Å²	10	27 Å²	27	6%	0.061	14%	0.143	C	C	.	.	I	π-helix	trans	-65.4	-49.5	-178.3	176	0	0	0	0	111.8	C119 I122 I476 G484	C119-V480 VanDerWaalsContact SG-CG1 3.57Å; C119-V480 PolarHBondContact SG-O 2.74Å; I122-V480 HydrophobicContact CD1-CB 4.38Å; I122-V480 HydrophobicContact CD1-CG1 3.85Å; I122-V480 HydrophobicContact CD1-CG2 4.5Å; I476-V480 HydrophobicContact CG2-CG2 4Å; I476-V480 VanDerWaalsContact O-CB 3.31Å; I476-V480 WeakPolarHBondContact O-CB 2.96Å; I476-V480 VanDerWaalsContact O-CG2 3.31Å; I476-V480 WeakPolarHBondContact O-CG2 3.38Å; I476-V480 PolarHBondContact O-N 3.03Å; V480-G484 WeakPolarHBondContact O-CA 3.19Å; V480-G484 PolarHBondContact O-N 3.18Å
481	F	87.6	Confident	87.6	Confident	52 Å²	52	27 Å²	27	23%	0.228	14%	0.143	C	C	.	.	I	π-helix	trans	-74.9	-52.4	179.8	-74.6	-94.9	0	0	0	112.3	C119 I122 F477 M485	C119-F481 HydrophobicContact CB-CD1 4.31Å; C119-F481 HydrophobicContact CB-CE1 4.11Å; C119-F481 HydrophobicContact CB-CZ 4.44Å; I122-F481 HydrophobicContact CB-CE2 4.36Å; I122-F481 HydrophobicContact CB-CZ 4.47Å; I122-F481 HydrophobicContact CG2-CE2 4Å; I122-F481 HydrophobicContact CG2-CZ 4.32Å; F477-F481 AromaticContact CD1-CD2 3.69Å; F477-F481 HydrophobicContact CD1-CD2 3.69Å; F477-F481 AromaticContact CD1-CE2 3.41Å; F477-F481 HydrophobicContact CD1-CE2 3.41Å; F477-F481 VanDerWaalsContact CD1-CE2 3.41Å; F477-F481 HydrophobicContact CD1-CZ 4.4Å; F477-F481 HydrophobicContact CE1-CD2 4.28Å; F477-F481 AromaticContact CE1-CE2 3.53Å; F477-F481 HydrophobicContact CE1-CE2 3.53Å; F477-F481 HydrophobicContact CE1-CZ 4.22Å; F477-F481 HydrophobicContact CG-CD2 4.47Å; F477-F481 HydrophobicContact CG-CE2 4.43Å; F477-F481 WeakPolarHBondContact O-CB 3.24Å; F477-F481 WeakPolarHBondContact O-CD2 3.45Å; F477-F481 PolarHBondContact O-N 2.95Å; F481-M485 WeakPolarHBondContact O-CB 3.16Å; F481-M485 WeakPolarHBondContact O-CG 3.43Å; F481-M485 PolarHBondContact O-N 2.77Å; F481-M485 VanDerWaalsContact O-SD 3.37Å
482	V	88.9	Confident	87.3	Confident	66 Å²	66	30.2 Å²	30.2	40%	0.4	16%	0.158	S	C	.	.	I	π-helix	trans	-75.4	-57.5	-173.8	-172.7	0	0	0	0	110.9	F478 T486	F478-V482 HydrophobicContact CD2-CB 4.28Å; F478-V482 HydrophobicContact CD2-CG2 3.72Å; F478-V482 HydrophobicContact CE2-CB 4.14Å; F478-V482 HydrophobicContact CE2-CG1 4.27Å; F478-V482 HydrophobicContact CE2-CG2 3.83Å; F478-V482 HydrophobicContact CG-CG2 4.36Å; F478-V482 HydrophobicContact CZ-CB 4.34Å; F478-V482 HydrophobicContact CZ-CG1 4.3Å; F478-V482 WeakPolarHBondContact O-CA 3.45Å; F478-V482 WeakPolarHBondContact O-CB 3.35Å; F478-V482 WeakPolarHBondContact O-CG2 3.45Å; F478-V482 PolarHBondContact O-N 3.39Å; V482-T486 WeakPolarHBondContact O-CB 3.37Å; V482-T486 VanDerWaalsContact O-CG2 3.24Å; V482-T486 WeakPolarHBondContact O-CG2 3.45Å; V482-T486 PolarHBondContact O-N 3.06Å; V482-T486 PolarHBondContact O-OG1 3.34Å
483	Q	87.7	Confident	86.9	Confident	13 Å²	13	36.3 Å²	36.3	6%	0.061	19%	0.19	C	C	.	.	I	π-helix	trans	-74.1	-33.6	-177.1	-56.3	178	-76.2	0	0	112.2	Y440 L443 T479 T486 I487	Y440-Q483 HydrophobicContact CE1-CB 3.86Å; Y440-Q483 HydrophobicContact CE1-CG 4.23Å; Y440-Q483 PolarHBondContact O-NE2 3.29Å; L443-Q483 HydrophobicContact CD2-CB 3.5Å; T479-Q483 VanDerWaalsContact CB-OE1 3.24Å; T479-Q483 CarbonylContact O-C 3.51Å; T479-Q483 WeakPolarHBondContact O-CA 3.46Å; T479-Q483 VanDerWaalsContact O-CB 3.26Å; T479-Q483 WeakPolarHBondContact O-CB 3Å; T479-Q483 PolarHBondContact O-N 3.25Å; Q483-T486 WeakPolarHBondContact CA-OG1 3.39Å; Q483-T486 PolarHBondContact O-N 3.25Å; Q483-T486 PolarHBondContact O-OG1 3.28Å; Q483-I487 WeakPolarHBondContact O-CB 3.44Å; Q483-I487 PolarHBondContact O-N 3.12Å
484	G	86.6	Confident	86.3	Confident	3 Å²	3	37.9 Å²	37.9	3%	0.031	20%	0.198	C	C	.	.	H	α-helix	trans	-67.1	-41.9	176.6	0	0	0	0	0	113.4	P116 T479 V480 I487	P116-G484 WeakPolarHBondContact CG-O 3.41Å; T479-G484 PolarHBondContact O-N 3Å; V480-G484 WeakPolarHBondContact O-CA 3.19Å; V480-G484 PolarHBondContact O-N 3.18Å; G484-I487 VanDerWaalsContact O-CG2 3.28Å; G484-I487 WeakPolarHBondContact O-CG2 3.37Å
485	M	85.3	Confident	85.2	Confident	73 Å²	73	37.7 Å²	37.7	36%	0.36	20%	0.199	S	C	.	.	H	α-helix	trans	-70.5	-31.4	175.5	-68.2	171.2	123	0	0	112.5	V115 F481	V115-M485 HydrophobicContact CB-CE 4.37Å; V115-M485 HydrophobicContact CG1-CE 4.14Å; V115-M485 HydrophobicContact CG2-CE 3.69Å; F481-M485 WeakPolarHBondContact O-CB 3.16Å; F481-M485 WeakPolarHBondContact O-CG 3.43Å; F481-M485 PolarHBondContact O-N 2.77Å; F481-M485 VanDerWaalsContact O-SD 3.37Å
486	T	88.6	Confident	83.5	Confident	50 Å²	50	43.6 Å²	43.6	31%	0.307	24%	0.235	S	C	.	.	H	α-helix	trans	-89.4	-15.9	-176.8	59.4	0	0	0	0	114.4	Y440 V482 Q483 R488 P489 L490	Y440-T486 WeakPolarHBondContact CE1-OG1 3.37Å; Y440-T486 PolarHBondContact OH-OG1 3.03Å; V482-T486 WeakPolarHBondContact O-CB 3.37Å; V482-T486 VanDerWaalsContact O-CG2 3.24Å; V482-T486 WeakPolarHBondContact O-CG2 3.45Å; V482-T486 PolarHBondContact O-N 3.06Å; V482-T486 PolarHBondContact O-OG1 3.34Å; Q483-T486 WeakPolarHBondContact CA-OG1 3.39Å; Q483-T486 PolarHBondContact O-N 3.25Å; Q483-T486 PolarHBondContact O-OG1 3.28Å; T486-R488 VanDerWaalsContact C-N 3.31Å; T486-R488 PolarHBondContact O-N 3.08Å; T486-P489 VanDerWaalsContact O-CD 3.27Å; T486-P489 WeakPolarHBondContact O-CD 3.28Å; T486-P489 WeakPolarHBondContact O-CG 3.05Å; T486-L490 WeakPolarHBondContact O-CB 3.33Å; T486-L490 PolarHBondContact O-N 3.21Å
487	I	86.3	Confident	81.6	Confident	1 Å²	1	51.4 Å²	51.4	1%	0.005	27%	0.269	C	S	.	.	H	α-helix	trans	-57	-43.5	-178.9	-170.6	68.9	0	0	0	111.7	V228 V231 Y440 Q483 G484 L490 V491	V228-I487 HydrophobicContact CG1-CD1 4.26Å; V228-I487 HydrophobicContact CG1-CG1 4.13Å; V228-I487 HydrophobicContact CG2-CD1 4.49Å; V228-I487 HydrophobicContact CG2-CG1 4.16Å; V231-I487 HydrophobicContact CG2-CG2 4.13Å; Y440-I487 HydrophobicContact CD1-CD1 3.87Å; Q483-I487 WeakPolarHBondContact O-CB 3.44Å; Q483-I487 PolarHBondContact O-N 3.12Å; G484-I487 VanDerWaalsContact O-CG2 3.28Å; G484-I487 WeakPolarHBondContact O-CG2 3.37Å; I487-L490 PolarHBondContact O-N 3.03Å; I487-V491 HydrophobicContact CD1-CG2 3.81Å; I487-V491 HydrophobicContact CG1-CG2 3.91Å; I487-V491 VanDerWaalsContact O-CB 3.24Å; I487-V491 WeakPolarHBondContact O-CB 3.27Å; I487-V491 WeakPolarHBondContact O-CG2 3.43Å; I487-V491 PolarHBondContact O-N 3.19Å
488	R	83.4	Confident	79.7	Confident	38 Å²	38	55 Å²	55	14%	0.143	29%	0.285	C	S	.	.	H	α-helix	trans	-59.8	-60.7	-179	-176.1	-172.7	-170.5	121	14.5	112.7	H113 V231 E234 T486 L490 V491 E492	H113-R488 PolarHBondContact CE1-NE 3.49Å; H113-R488 PolarHBondContact NE2-NE 2.88Å; H113-R488 PolarHBondContact NE2-NH2 2.87Å; H113-R488 WeakPolarHBondContact O-CD 3.01Å; V231-R488 HydrophobicContact CG1-CB 4.12Å; V231-R488 HydrophobicContact CG1-CG 4.35Å; V231-R488 HydrophobicContact CG2-CB 4.09Å; E234-R488 IonicContact OE1-NH1 3.69Å; E234-R488 IonicContact OE2-CZ 2.69Å; E234-R488 IonicContact OE2-NH1 3.12Å; E234-R488 PolarHBondContact OE2-NH1 3.29Å; E234-R488 IonicContact OE2-NH2 3.93Å; E234-R488 PolarHBondContact OE2-NH2 2.95Å; T486-R488 VanDerWaalsContact C-N 3.31Å; T486-R488 PolarHBondContact O-N 3.08Å; R488-L490 VanDerWaalsContact C-N 3.25Å; R488-L490 PolarHBondContact O-N 3.18Å; R488-V491 PolarHBondContact O-N 2.98Å; R488-E492 WeakPolarHBondContact CG-OE1 3.47Å; R488-E492 IonicContact CZ-OE1 2.77Å; R488-E492 IonicContact NE-OE1 3.88Å; R488-E492 PolarHBondContact NE-OE1 2.98Å; R488-E492 VanDerWaalsContact NE-OE1 3.09Å; R488-E492 IonicContact NH2-OE1 3.75Å; R488-E492 WeakPolarHBondContact O-CG 3.27Å; R488-E492 PolarHBondContact O-N 3.27Å
489	P	86.3	Confident	77.3	Confident	71 Å²	71	61.3 Å²	61.3	46%	0.461	31%	0.312	S	S	.	.	H	α-helix	trans	-63.1	-31.3	179.2	24.5	-34.5	0	0	0	112.7	T486 L493	T486-P489 VanDerWaalsContact O-CD 3.27Å; T486-P489 WeakPolarHBondContact O-CD 3.28Å; T486-P489 WeakPolarHBondContact O-CG 3.05Å; P489-L493 WeakPolarHBondContact O-CB 3.35Å; P489-L493 PolarHBondContact O-N 3.19Å
490	L	85.6	Confident	74.9	Confident	37 Å²	37	70.6 Å²	70.6	19%	0.194	35%	0.352	C	S	.	.	H	α-helix	trans	-65.6	-46.9	175.9	-173.1	66.8	0	0	0	111.7	F436 Y440 T486 I487 R488 L493 L494	F436-L490 HydrophobicContact CE1-CD1 4.02Å; F436-L490 HydrophobicContact CE1-CD2 3.87Å; F436-L490 HydrophobicContact CE1-CG 4.18Å; F436-L490 HydrophobicContact CZ-CD2 4.39Å; Y440-L490 HydrophobicContact CD1-CD2 3.42Å; Y440-L490 VanDerWaalsContact CD1-CD2 3.42Å; Y440-L490 HydrophobicContact CD2-CD2 3.84Å; Y440-L490 HydrophobicContact CE1-CD2 3.64Å; Y440-L490 HydrophobicContact CE2-CD2 4.05Å; Y440-L490 HydrophobicContact CG-CD2 3.52Å; T486-L490 WeakPolarHBondContact O-CB 3.33Å; T486-L490 PolarHBondContact O-N 3.21Å; I487-L490 PolarHBondContact O-N 3.03Å; R488-L490 VanDerWaalsContact C-N 3.25Å; R488-L490 PolarHBondContact O-N 3.18Å; L490-L493 PolarHBondContact O-N 3.18Å; L490-L494 HydrophobicContact CD1-CD1 4.02Å; L490-L494 HydrophobicContact CG-CD1 4.27Å; L490-L494 WeakPolarHBondContact O-CD1 3.44Å; L490-L494 PolarHBondContact O-N 3.32Å
491	V	81.3	Confident	73	Confident	1 Å²	1	77 Å²	77	1%	0.006	38%	0.382	C	S	.	.	H	α-helix	trans	-66.6	-43.8	178.3	169.4	0	0	0	0	110.7	F232 I235 I237 I437 I487 R488 L493 L494 A495	F232-V491 HydrophobicContact CE1-CG2 3.95Å; I235-V491 HydrophobicContact CD1-CB 4.21Å; I235-V491 HydrophobicContact CD1-CG1 3.62Å; I235-V491 HydrophobicContact CG2-CG1 4.37Å; I237-V491 HydrophobicContact CD1-CG1 3.35Å; I237-V491 HydrophobicContact CG1-CG1 4.45Å; I437-V491 HydrophobicContact CG2-CG2 4.47Å; I487-V491 HydrophobicContact CD1-CG2 3.81Å; I487-V491 HydrophobicContact CG1-CG2 3.91Å; I487-V491 VanDerWaalsContact O-CB 3.24Å; I487-V491 WeakPolarHBondContact O-CB 3.27Å; I487-V491 WeakPolarHBondContact O-CG2 3.43Å; I487-V491 PolarHBondContact O-N 3.19Å; R488-V491 PolarHBondContact O-N 2.98Å; V491-L493 PolarHBondContact O-N 3.4Å; V491-L494 PolarHBondContact O-N 3.31Å; V491-A495 WeakPolarHBondContact O-CB 3.4Å; V491-A495 PolarHBondContact O-N 3.14Å
492	E	81.6	Confident	71	Confident	69 Å²	69	79.2 Å²	79.2	32%	0.322	40%	0.403	S	S	.	.	H	α-helix	trans	-57.5	-48.5	173.5	-71.4	175.2	-168	0	0	110.8	I235 R488 L494 A495 V496	I235-E492 HydrophobicContact CD1-CG 3.69Å; I235-E492 HydrophobicContact CG1-CG 4.43Å; R488-E492 WeakPolarHBondContact CG-OE1 3.47Å; R488-E492 IonicContact CZ-OE1 2.77Å; R488-E492 IonicContact NE-OE1 3.88Å; R488-E492 PolarHBondContact NE-OE1 2.98Å; R488-E492 VanDerWaalsContact NE-OE1 3.09Å; R488-E492 IonicContact NH2-OE1 3.75Å; R488-E492 WeakPolarHBondContact O-CG 3.27Å; R488-E492 PolarHBondContact O-N 3.27Å; E492-L494 PolarHBondContact O-N 2.9Å; E492-A495 CarbonylContact O-C 3.59Å; E492-A495 PolarHBondContact O-N 3.35Å; E492-A495 VanDerWaalsContact O-N 3.16Å; E492-V496 VanDerWaalsContact O-CG2 3.31Å; E492-V496 WeakPolarHBondContact O-CG2 3.49Å; E492-V496 PolarHBondContact O-N 2.87Å
493	L	82.1	Confident	69.1	Low	129 Å²	129	83.7 Å²	83.7	68%	0.675	42%	0.417	S	S	*	.	H	α-helix	trans	-59	-41.2	177.5	-177.9	66.3	0	0	0	113	P489 L490 V491	P489-L493 WeakPolarHBondContact O-CB 3.35Å; P489-L493 PolarHBondContact O-N 3.19Å; L490-L493 PolarHBondContact O-N 3.18Å; V491-L493 PolarHBondContact O-N 3.4Å
494	L	76.1	Confident	67.5	Low	38 Å²	38	85.9 Å²	85.9	20%	0.199	43%	0.433	C	S	.	.	H	α-helix	trans	-74.1	-34	176.4	-89	78.2	0	0	0	112.5	K433 F436 I437 L490 V491 E492	K433-L494 HydrophobicContact CB-CD2 4.28Å; F436-L494 HydrophobicContact CD1-CD2 3.81Å; F436-L494 HydrophobicContact CE1-CD2 4.45Å; I437-L494 HydrophobicContact CD1-CB 4.3Å; I437-L494 HydrophobicContact CD1-CD2 4Å; I437-L494 HydrophobicContact CG1-CD2 3.84Å; L490-L494 HydrophobicContact CD1-CD1 4.02Å; L490-L494 HydrophobicContact CG-CD1 4.27Å; L490-L494 WeakPolarHBondContact O-CD1 3.44Å; L490-L494 PolarHBondContact O-N 3.32Å; V491-L494 PolarHBondContact O-N 3.31Å; E492-L494 PolarHBondContact O-N 2.9Å
495	A	65.1	Low	66.2	Low	28 Å²	28	88.6 Å²	88.6	23%	0.231	45%	0.451	C	S	.	.	H	α-helix	trans	-83.9	-17.7	-176.1	0	0	0	0	0	114.3	I235 V491 E492 K497 K498	I235-A495 HydrophobicContact CG2-CB 4.32Å; V491-A495 WeakPolarHBondContact O-CB 3.4Å; V491-A495 PolarHBondContact O-N 3.14Å; E492-A495 CarbonylContact O-C 3.59Å; E492-A495 PolarHBondContact O-N 3.35Å; E492-A495 VanDerWaalsContact O-N 3.16Å; A495-K497 PolarHBondContact O-N 3.32Å; A495-K498 WeakPolarHBondContact O-CA 3.34Å; A495-K498 VanDerWaalsContact O-CB 3.31Å; A495-K498 WeakPolarHBondContact O-CB 3.07Å; A495-K498 PolarHBondContact O-N 3.1Å
496	V	56.1	Low	65.1	Low	128 Å²	128	88.5 Å²	88.5	78%	0.776	45%	0.452	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.1	-21.7	170.2	160.6	0	0	0	0	112.2	E492 K498	E492-V496 VanDerWaalsContact O-CG2 3.31Å; E492-V496 WeakPolarHBondContact O-CG2 3.49Å; E492-V496 PolarHBondContact O-N 2.87Å; V496-K498 VanDerWaalsContact C-N 3.28Å; V496-K498 PolarHBondContact O-N 3.16Å
497	K	49	Very low	63.8	Low	167 Å²	167	90.8 Å²	90.8	73%	0.726	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.1	35.7	168.7	-67.8	-175.6	177.6	178	0	113.5	A495 K499	A495-K497 PolarHBondContact O-N 3.32Å; K497-K499 PolarHBondContact O-N 3.37Å
498	K	49.8	Very low	62.9	Low	116 Å²	116	95.8 Å²	95.8	50%	0.504	49%	0.485	S	S	.	.			trans	-61.9	107.9	-179.2	-138.5	167.1	-174.7	171.1	0	109.6	I235 H236 A495 V496 K500	I235-K498 PolarHBondContact O-NZ 3.33Å; H236-K498 PolarHBondContact O-NZ 2.95Å; A495-K498 WeakPolarHBondContact O-CA 3.34Å; A495-K498 VanDerWaalsContact O-CB 3.31Å; A495-K498 WeakPolarHBondContact O-CB 3.07Å; A495-K498 PolarHBondContact O-N 3.1Å; V496-K498 VanDerWaalsContact C-N 3.28Å; V496-K498 PolarHBondContact O-N 3.16Å; K498-K500 PolarHBondContact O-N 3.47Å; K498-K500 VanDerWaalsContact O-N 3.13Å
499	K	40.5	Very low	62	Low	194 Å²	194	96.5 Å²	96.5	84%	0.843	49%	0.49	S	S	*	.			trans	-60.1	118.5	164.2	-171.9	178.1	-179.1	-174.7	0	105.6	K497 E501	K497-K499 PolarHBondContact O-N 3.37Å; K499-E501 PolarHBondContact O-N 3.44Å
500	K	38.8	Very low	61.3	Low	198 Å²	198	95.9 Å²	95.9	86%	0.861	48%	0.482	S	S	*	.			trans	-53.7	110.2	-175.2	-156.9	176.6	-167.1	175.1	0	108.3	K498 S502	K498-K500 PolarHBondContact O-N 3.47Å; K498-K500 VanDerWaalsContact O-N 3.13Å; K500-S502 PolarHBondContact O-N 3.09Å
501	E	46.9	Very low	60.5	Low	146 Å²	146	98.9 Å²	98.9	68%	0.682	50%	0.495	S	S	*	.			trans	-68.9	84.6	169	-74.4	-165.9	-174.3	0	0	107.6	K499 K503	K499-E501 PolarHBondContact O-N 3.44Å; E501-K503 PolarHBondContact O-N 3.4Å
502	S	44.6	Very low	59.9	Low	97 Å²	97	102.3 Å²	102.3	68%	0.678	52%	0.516	S	S	*	.	P	Polyproline II helix	trans	-57.9	123.7	151.2	-171.6	0	0	0	0	105.5	K500	K500-S502 PolarHBondContact O-N 3.09Å
503	K	49.7	Very low	59.2	Low	160 Å²	160	101.2 Å²	101.2	70%	0.696	51%	0.511	S	S	*	.	P	Polyproline II helix	trans	-48.9	138.4	157.3	-63.6	-175.7	177.1	-170	0	106.7	E501 S505	E501-K503 PolarHBondContact O-N 3.4Å; K503-S505 PolarHBondContact O-N 2.86Å
504	P	54.9	Low	58.8	Low	59 Å²	59	100.1 Å²	100.1	38%	0.383	50%	0.501	S	S	.	.	P	Polyproline II helix	trans	-51.1	138.8	177.2	22	-32.7	0	0	0	108	E508 E509	P504-E508 VanDerWaalsContact CA-OE2 3.24Å; P504-E508 WeakPolarHBondContact CA-OE2 3.32Å; P504-E508 HydrophobicContact CB-CB 4.13Å; P504-E508 HydrophobicContact CB-CG 3.92Å; P504-E508 WeakPolarHBondContact CB-OE2 3.33Å; P504-E509 HydrophobicContact CG-CB 4.47Å
505	S	58.3	Low	58.7	Low	60 Å²	60	103 Å²	103	42%	0.42	52%	0.516	S	S	.	.	P	Polyproline II helix	trans	-58.5	153.6	-179.2	73	0	0	0	0	109.2	K503 N507 E508 E509	K503-S505 PolarHBondContact O-N 2.86Å; S505-N507 PolarHBondContact O-N 3.08Å; S505-E508 PolarHBondContact N-OE2 3.47Å; S505-E508 VanDerWaalsContact N-OE2 3.14Å; S505-E508 WeakPolarHBondContact O-CA 3.06Å; S505-E508 WeakPolarHBondContact O-CB 3.27Å; S505-E508 PolarHBondContact O-N 3.23Å; S505-E508 WeakPolarHBondContact OG-CB 3.47Å; S505-E508 PolarHBondContact OG-N 3.14Å; S505-E508 VanDerWaalsContact OG-N 3.07Å; S505-E509 PolarHBondContact O-N 3.22Å
506	I	61.3	Low	58.6	Low	72 Å²	72	104.9 Å²	104.9	37%	0.369	52%	0.522	S	S	.	.	H	α-helix	trans	-52.7	-35.1	176.9	-78.6	79.1	0	0	0	110.3	I510	I506-I510 HydrophobicContact CG2-CD1 3.58Å; I506-I510 HydrophobicContact CG2-CG1 4.38Å; I506-I510 WeakPolarHBondContact O-CB 3.42Å; I506-I510 WeakPolarHBondContact O-CD1 3.21Å; I506-I510 WeakPolarHBondContact O-CG1 3.37Å; I506-I510 PolarHBondContact O-N 3.47Å
507	N	63.1	Low	59	Low	98 Å²	98	101.6 Å²	101.6	52%	0.524	50%	0.498	S	S	.	.	H	α-helix	trans	-67.3	-42	176.3	-160.5	47	0	0	0	113	S505 H511	S505-N507 PolarHBondContact O-N 3.08Å; N507-H511 PolarHBondContact ND2-CD2 3.04Å; N507-H511 PolarHBondContact ND2-NE2 3.27Å; N507-H511 WeakPolarHBondContact O-CB 3.14Å; N507-H511 PolarHBondContact O-CD2 2.95Å; N507-H511 PolarHBondContact O-N 3.4Å; N507-H511 PolarHBondContact OD1-NE2 3.3Å
508	E	66.7	Low	60.1	Low	106 Å²	106	97.4 Å²	97.4	50%	0.495	48%	0.484	S	S	.	.	H	α-helix	trans	-65	-47.5	176.2	-174.8	177.4	-168.9	0	0	111.3	P504 S505 I510 H511 T512	P504-E508 VanDerWaalsContact CA-OE2 3.24Å; P504-E508 WeakPolarHBondContact CA-OE2 3.32Å; P504-E508 HydrophobicContact CB-CB 4.13Å; P504-E508 HydrophobicContact CB-CG 3.92Å; P504-E508 WeakPolarHBondContact CB-OE2 3.33Å; S505-E508 PolarHBondContact N-OE2 3.47Å; S505-E508 VanDerWaalsContact N-OE2 3.14Å; S505-E508 WeakPolarHBondContact O-CA 3.06Å; S505-E508 WeakPolarHBondContact O-CB 3.27Å; S505-E508 PolarHBondContact O-N 3.23Å; S505-E508 WeakPolarHBondContact OG-CB 3.47Å; S505-E508 PolarHBondContact OG-N 3.14Å; S505-E508 VanDerWaalsContact OG-N 3.07Å; E508-I510 PolarHBondContact O-N 3Å; E508-H511 PolarHBondContact O-N 2.92Å; E508-T512 PolarHBondContact O-N 3.26Å; E508-T512 PolarHBondContact O-OG1 3.3Å; E508-T512 VanDerWaalsContact O-OG1 3.05Å
509	E	65	Low	60.9	Low	53 Å²	53	95.7 Å²	95.7	25%	0.248	48%	0.48	C	S	.	.	H	α-helix	trans	-63.6	-39.2	178	-161.4	-175.5	155	0	0	111.9	P504 S505 Q513 R620 R624	P504-E509 HydrophobicContact CG-CB 4.47Å; S505-E509 PolarHBondContact O-N 3.22Å; E509-Q513 VanDerWaalsContact O-CB 3.23Å; E509-Q513 WeakPolarHBondContact O-CB 3.34Å; E509-Q513 PolarHBondContact O-N 2.99Å; E509-R620 IonicContact OE2-NH1 3.83Å; E509-R624 IonicContact OE1-CZ 2.74Å; E509-R624 IonicContact OE1-NE 3.93Å; E509-R624 PolarHBondContact OE1-NE 3.06Å; E509-R624 IonicContact OE1-NH2 2.66Å; E509-R624 PolarHBondContact OE1-NH2 2.79Å; E509-R624 IonicContact OE2-NH2 3.18Å
510	I	70.6	Confident	61.9	Low	58 Å²	58	86.8 Å²	86.8	30%	0.297	44%	0.441	S	S	.	.	H	α-helix	trans	-65	-44.9	173.2	-70.9	167.8	0	0	0	111	I506 E508 Q513 F514 L623	I506-I510 HydrophobicContact CG2-CD1 3.58Å; I506-I510 HydrophobicContact CG2-CG1 4.38Å; I506-I510 WeakPolarHBondContact O-CB 3.42Å; I506-I510 WeakPolarHBondContact O-CD1 3.21Å; I506-I510 WeakPolarHBondContact O-CG1 3.37Å; I506-I510 PolarHBondContact O-N 3.47Å; E508-I510 PolarHBondContact O-N 3Å; I510-Q513 PolarHBondContact O-N 2.7Å; I510-F514 VanDerWaalsContact O-CB 3.23Å; I510-F514 WeakPolarHBondContact O-CB 3.31Å; I510-F514 PolarHBondContact O-N 3.06Å; I510-L623 HydrophobicContact CD1-CD1 4.11Å
511	H	68.7	Low	63.3	Low	99 Å²	99	78.7 Å²	78.7	46%	0.458	41%	0.414	S	S	.	.	H	α-helix	trans	-67.2	-42.1	179.9	-81	-55.8	0	0	0	112.5	N507 E508 F514 L515	N507-H511 PolarHBondContact ND2-CD2 3.04Å; N507-H511 PolarHBondContact ND2-NE2 3.27Å; N507-H511 WeakPolarHBondContact O-CB 3.14Å; N507-H511 PolarHBondContact O-CD2 2.95Å; N507-H511 PolarHBondContact O-N 3.4Å; N507-H511 PolarHBondContact OD1-NE2 3.3Å; E508-H511 PolarHBondContact O-N 2.92Å; H511-F514 PolarHBondContact O-N 2.88Å; H511-L515 VanDerWaalsContact O-CB 3.29Å; H511-L515 WeakPolarHBondContact O-CB 3.45Å; H511-L515 VanDerWaalsContact O-CG 3.23Å; H511-L515 WeakPolarHBondContact O-CG 3.42Å; H511-L515 PolarHBondContact O-N 2.96Å
512	T	69.1	Low	64.5	Low	73 Å²	73	75.6 Å²	75.6	45%	0.448	40%	0.402	S	S	.	.	H	α-helix	trans	-62.5	-47.2	174.3	-53.5	0	0	0	0	110.7	E508 F514 L515 D516	E508-T512 PolarHBondContact O-N 3.26Å; E508-T512 PolarHBondContact O-OG1 3.3Å; E508-T512 VanDerWaalsContact O-OG1 3.05Å; T512-F514 VanDerWaalsContact C-N 3.34Å; T512-F514 PolarHBondContact O-N 3.11Å; T512-L515 PolarHBondContact O-N 3.3Å; T512-D516 PolarHBondContact O-N 3Å
513	Q	67.4	Low	65.7	Low	46 Å²	46	72.2 Å²	72.2	22%	0.215	38%	0.375	C	S	.	.	H	α-helix	trans	-65.7	-34.7	179	-177.3	156.6	69.4	0	0	113	E509 I510 H517	E509-Q513 VanDerWaalsContact O-CB 3.23Å; E509-Q513 WeakPolarHBondContact O-CB 3.34Å; E509-Q513 PolarHBondContact O-N 2.99Å; I510-Q513 PolarHBondContact O-N 2.7Å; Q513-H517 WeakPolarHBondContact O-CB 3.19Å; Q513-H517 PolarHBondContact O-CD2 3.18Å; Q513-H517 VanDerWaalsContact O-CG 3.26Å; Q513-H517 PolarHBondContact O-N 2.75Å; Q513-H517 VanDerWaalsContact O-N 3.15Å
514	F	73.6	Confident	66.3	Low	106 Å²	106	67.9 Å²	67.9	47%	0.465	36%	0.36	S	S	.	.	H	α-helix	trans	-67.4	-44	171.7	175.7	-99.9	0	0	0	111.8	I510 H511 T512 H517 L518	I510-F514 VanDerWaalsContact O-CB 3.23Å; I510-F514 WeakPolarHBondContact O-CB 3.31Å; I510-F514 PolarHBondContact O-N 3.06Å; H511-F514 PolarHBondContact O-N 2.88Å; T512-F514 VanDerWaalsContact C-N 3.34Å; T512-F514 PolarHBondContact O-N 3.11Å; F514-H517 PolarHBondContact O-N 3.48Å; F514-L518 HydrophobicContact CE1-CD1 3.84Å; F514-L518 HydrophobicContact CZ-CD1 3.87Å; F514-L518 VanDerWaalsContact O-CB 3.29Å; F514-L518 WeakPolarHBondContact O-CB 3.4Å; F514-L518 PolarHBondContact O-N 3.27Å
515	L	73	Confident	67.1	Low	99 Å²	99	72.2 Å²	72.2	52%	0.518	38%	0.378	S	S	.	.	H	α-helix	trans	-63.7	-40.7	176.9	-76.7	168.4	0	0	0	111.8	H511 T512 H517 L518 L519	H511-L515 VanDerWaalsContact O-CB 3.29Å; H511-L515 WeakPolarHBondContact O-CB 3.45Å; H511-L515 VanDerWaalsContact O-CG 3.23Å; H511-L515 WeakPolarHBondContact O-CG 3.42Å; H511-L515 PolarHBondContact O-N 2.96Å; T512-L515 PolarHBondContact O-N 3.3Å; L515-H517 VanDerWaalsContact C-N 3.35Å; L515-H517 PolarHBondContact O-N 3.12Å; L515-L518 PolarHBondContact O-N 3.36Å; L515-L519 WeakPolarHBondContact O-CB 3.36Å; L515-L519 PolarHBondContact O-N 3.22Å
516	D	63.1	Low	67.5	Low	68 Å²	68	73.4 Å²	73.4	36%	0.364	39%	0.385	S	S	.	.	H	α-helix	trans	-61.8	-42.9	174.3	-71.5	-16.6	0	0	0	111.2	T512 T520	T512-D516 PolarHBondContact O-N 3Å; D516-T520 WeakPolarHBondContact O-CB 3.43Å; D516-T520 PolarHBondContact O-N 3.47Å; D516-T520 PolarHBondContact O-OG1 3.26Å
517	H	66	Low	67.4	Low	58 Å²	58	72.3 Å²	72.3	27%	0.269	39%	0.392	S	S	.	.	H	α-helix	trans	-68.8	-37.1	176.8	-70.6	-25.2	0	0	0	113	Q513 F514 L515 G521	Q513-H517 WeakPolarHBondContact O-CB 3.19Å; Q513-H517 PolarHBondContact O-CD2 3.18Å; Q513-H517 VanDerWaalsContact O-CG 3.26Å; Q513-H517 PolarHBondContact O-N 2.75Å; Q513-H517 VanDerWaalsContact O-N 3.15Å; F514-H517 PolarHBondContact O-N 3.48Å; L515-H517 VanDerWaalsContact C-N 3.35Å; L515-H517 PolarHBondContact O-N 3.12Å; H517-G521 PolarHBondContact O-N 3.09Å
518	L	71.1	Confident	67.4	Low	80 Å²	80	74.8 Å²	74.8	42%	0.419	40%	0.4	S	S	.	.	H	α-helix	trans	-69.3	-42.6	175	-179.1	139.8	0	0	0	111.2	F514 L515 G521 I522	F514-L518 HydrophobicContact CE1-CD1 3.84Å; F514-L518 HydrophobicContact CZ-CD1 3.87Å; F514-L518 VanDerWaalsContact O-CB 3.29Å; F514-L518 WeakPolarHBondContact O-CB 3.4Å; F514-L518 PolarHBondContact O-N 3.27Å; L515-L518 PolarHBondContact O-N 3.36Å; L518-G521 PolarHBondContact O-N 3.43Å; L518-I522 HydrophobicContact CD2-CD1 3.57Å; L518-I522 HydrophobicContact CG-CD1 4.29Å; L518-I522 WeakPolarHBondContact O-CG1 3.2Å; L518-I522 PolarHBondContact O-N 2.96Å
519	L	66.8	Low	66.9	Low	80 Å²	80	77.8 Å²	77.8	42%	0.419	41%	0.408	S	S	.	.	H	α-helix	trans	-62.2	-43.3	174	-176.4	65.7	0	0	0	111	L515 G521 I522 E523	L515-L519 WeakPolarHBondContact O-CB 3.36Å; L515-L519 PolarHBondContact O-N 3.22Å; L519-G521 VanDerWaalsContact C-N 3.31Å; L519-G521 PolarHBondContact O-N 2.89Å; L519-I522 CarbonylContact O-C 3.53Å; L519-I522 PolarHBondContact O-N 3.47Å; L519-E523 WeakPolarHBondContact O-CG 3.35Å; L519-E523 PolarHBondContact O-N 2.92Å
520	T	61.8	Low	66.7	Low	6 Å²	6	76.3 Å²	76.3	4%	0.037	41%	0.407	C	S	.	.	H	α-helix	trans	-63.1	-38.3	174.6	-50	0	0	0	0	111.5	D516 E523 D524 H532 R631	D516-T520 WeakPolarHBondContact O-CB 3.43Å; D516-T520 PolarHBondContact O-N 3.47Å; D516-T520 PolarHBondContact O-OG1 3.26Å; T520-E523 PolarHBondContact O-N 2.79Å; T520-D524 PolarHBondContact O-N 2.76Å; T520-H532 HydrophobicContact CG2-CB 4.34Å; T520-R631 VanDerWaalsContact CG2-NH2 3.27Å
521	G	68.6	Low	65.8	Low	29 Å²	29	79.4 Å²	79.4	30%	0.299	42%	0.42	S	S	.	.	H	α-helix	trans	-65.2	-37.9	173.5	0	0	0	0	0	113	H517 L518 L519 I525	H517-G521 PolarHBondContact O-N 3.09Å; L518-G521 PolarHBondContact O-N 3.43Å; L519-G521 VanDerWaalsContact C-N 3.31Å; L519-G521 PolarHBondContact O-N 2.89Å; G521-I525 WeakPolarHBondContact O-CD1 3.39Å; G521-I525 VanDerWaalsContact O-CG1 3.22Å; G521-I525 WeakPolarHBondContact O-CG1 3.38Å; G521-I525 PolarHBondContact O-N 3.49Å
522	I	71.2	Confident	65.2	Low	81 Å²	81	77.3 Å²	77.3	42%	0.415	41%	0.41	S	S	.	.	H	α-helix	trans	-69.3	-41.9	173.8	-68.7	169.9	0	0	0	110.9	L518 L519 D524 I525 C526	L518-I522 HydrophobicContact CD2-CD1 3.57Å; L518-I522 HydrophobicContact CG-CD1 4.29Å; L518-I522 WeakPolarHBondContact O-CG1 3.2Å; L518-I522 PolarHBondContact O-N 2.96Å; L519-I522 CarbonylContact O-C 3.53Å; L519-I522 PolarHBondContact O-N 3.47Å; I522-D524 VanDerWaalsContact C-N 3.34Å; I522-D524 PolarHBondContact O-N 3.21Å; I522-I525 PolarHBondContact O-N 3.13Å; I522-C526 VanDerWaalsContact O-CB 3.26Å; I522-C526 WeakPolarHBondContact O-CB 3.21Å; I522-C526 PolarHBondContact O-N 3.02Å; I522-C526 PolarHBondContact O-SG 3.27Å
523	E	69.1	Low	64.7	Low	26 Å²	26	75.1 Å²	75.1	12%	0.121	40%	0.395	C	S	.	.	H	α-helix	trans	-56.3	-47.3	173.2	-76.8	-179.9	-160.3	0	0	110.9	L519 T520 I525 G527 H528 G530 H532 H533	L519-E523 WeakPolarHBondContact O-CG 3.35Å; L519-E523 PolarHBondContact O-N 2.92Å; T520-E523 PolarHBondContact O-N 2.79Å; E523-I525 PolarHBondContact O-N 3.38Å; E523-G527 PolarHBondContact O-N 3.19Å; E523-H528 PolarHBondContact O-N 3.43Å; E523-G530 WeakPolarHBondContact OE2-CA 3.45Å; E523-H532 IonicContact OE1-ND1 3.86Å; E523-H532 PolarHBondContact OE1-ND1 3.28Å; E523-H533 PolarHBondContact OE2-N 2.68Å
524	D	63.9	Low	64.2	Low	69 Å²	69	80.7 Å²	80.7	37%	0.369	41%	0.414	S	S	.	.	H	α-helix	trans	-66.6	-32.1	178.1	-77.8	-21.5	0	0	0	112.7	T520 I522 H533 R631	T520-D524 PolarHBondContact O-N 2.76Å; I522-D524 VanDerWaalsContact C-N 3.34Å; I522-D524 PolarHBondContact O-N 3.21Å; D524-H533 IonicContact OD1-CE1 2.97Å; D524-H533 IonicContact OD1-ND1 3.25Å; D524-H533 PolarHBondContact OD1-ND1 3.45Å; D524-R631 IonicContact OD2-NH2 3.43Å
525	I	70.9	Confident	63.7	Low	149 Å²	149	79.9 Å²	79.9	76%	0.764	41%	0.41	S	S	*	.	H	α-helix	trans	-78.4	-41	175.9	-69.5	164.3	0	0	0	112.2	G521 I522 E523 G527	G521-I525 WeakPolarHBondContact O-CD1 3.39Å; G521-I525 VanDerWaalsContact O-CG1 3.22Å; G521-I525 WeakPolarHBondContact O-CG1 3.38Å; G521-I525 PolarHBondContact O-N 3.49Å; I522-I525 PolarHBondContact O-N 3.13Å; E523-I525 PolarHBondContact O-N 3.38Å; I525-G527 VanDerWaalsContact C-N 3.28Å; I525-G527 PolarHBondContact O-N 2.98Å
526	C	67.1	Low	63.2	Low	86 Å²	86	76.8 Å²	76.8	58%	0.581	39%	0.394	S	S	*	.	H	α-helix	trans	-79.8	-7.5	-179.4	-70	0	0	0	0	113.4	I522 H528	I522-C526 VanDerWaalsContact O-CB 3.26Å; I522-C526 WeakPolarHBondContact O-CB 3.21Å; I522-C526 PolarHBondContact O-N 3.02Å; I522-C526 PolarHBondContact O-SG 3.27Å; C526-H528 PolarHBondContact O-N 3.27Å
527	G	59.7	Low	63	Low	49 Å²	49	78.5 Å²	78.5	51%	0.505	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	65.2	16.6	-179.6	0	0	0	0	0	114.2	E523 I525	E523-G527 PolarHBondContact O-N 3.19Å; I525-G527 VanDerWaalsContact C-N 3.28Å; I525-G527 PolarHBondContact O-N 2.98Å
528	H	62.8	Low	62.9	Low	150 Å²	150	81.7 Å²	81.7	69%	0.694	42%	0.416	S	S	*	.			trans	-90.5	121.2	179.2	-107.8	67.6	0	0	0	110.1	E523 C526 G530	E523-H528 PolarHBondContact O-N 3.43Å; C526-H528 PolarHBondContact O-N 3.27Å; H528-G530 PolarHBondContact O-N 3.03Å
529	Y	55.6	Low	62.6	Low	169 Å²	169	81.3 Å²	81.3	66%	0.663	42%	0.415	S	S	*	.			trans	-77	80.9	-177.2	-63.8	-73.6	0	0	0	112.1	H533	Y529-H533 AromaticContact CD1-CD2 3.66Å; Y529-H533 AromaticContact CD1-NE2 3.79Å; Y529-H533 AromaticContact CE1-NE2 3.78Å
530	G	60	Low	62.6	Low	21 Å²	21	82.9 Å²	82.9	22%	0.216	42%	0.415	C	S	.	.			trans	-74.8	174.9	174.1	0	0	0	0	0	114.2	E523 H528 H532 H533 W534	E523-G530 WeakPolarHBondContact OE2-CA 3.45Å; H528-G530 PolarHBondContact O-N 3.03Å; G530-H532 PolarHBondContact O-N 3.48Å; G530-H533 PolarHBondContact O-N 3.32Å; G530-W534 PolarHBondContact O-N 3.38Å
531	H	53.2	Low	62.9	Low	124 Å²	124	87.9 Å²	87.9	57%	0.574	44%	0.437	S	S	*	.	H	α-helix	trans	-62	-33.7	177	-175.6	78	0	0	0	111.8	K535	H531-K535 WeakPolarHBondContact O-CB 3.34Å; H531-K535 PolarHBondContact O-N 3.33Å
532	H	55.7	Low	63.1	Low	54 Å²	54	88.2 Å²	88.2	25%	0.25	43%	0.432	C	S	.	.	H	α-helix	trans	-68.6	-43.7	177.8	-59.5	105.3	0	0	0	111.8	T520 E523 G530 W534 K535 D536	T520-H532 HydrophobicContact CG2-CB 4.34Å; E523-H532 IonicContact OE1-ND1 3.86Å; E523-H532 PolarHBondContact OE1-ND1 3.28Å; G530-H532 PolarHBondContact O-N 3.48Å; H532-W534 VanDerWaalsContact C-N 3.33Å; H532-W534 PolarHBondContact O-N 2.9Å; H532-K535 PolarHBondContact O-N 2.88Å; H532-D536 WeakPolarHBondContact O-CB 3.33Å; H532-D536 PolarHBondContact O-N 3.03Å
533	H	57.3	Low	62.8	Low	28 Å²	28	90.1 Å²	90.1	13%	0.13	44%	0.437	C	S	.	.	H	α-helix	trans	-56.5	-44.2	175.1	-173.9	97.7	0	0	0	112.6	E523 D524 Y529 G530 D536 K537	E523-H533 PolarHBondContact OE2-N 2.68Å; D524-H533 IonicContact OD1-CE1 2.97Å; D524-H533 IonicContact OD1-ND1 3.25Å; D524-H533 PolarHBondContact OD1-ND1 3.45Å; Y529-H533 AromaticContact CD1-CD2 3.66Å; Y529-H533 AromaticContact CD1-NE2 3.79Å; Y529-H533 AromaticContact CE1-NE2 3.78Å; G530-H533 PolarHBondContact O-N 3.32Å; H533-D536 PolarHBondContact O-N 3.36Å; H533-K537 VanDerWaalsContact O-CB 3.26Å; H533-K537 WeakPolarHBondContact O-CB 3.48Å; H533-K537 PolarHBondContact O-N 2.9Å
534	W	58.9	Low	62.5	Low	163 Å²	163	92.7 Å²	92.7	62%	0.617	45%	0.454	S	S	*	.	H	α-helix	trans	-67.8	-42.6	176.6	-86	96.1	0	0	0	113	G530 H532 D536 K537 L538	G530-W534 PolarHBondContact O-N 3.38Å; H532-W534 VanDerWaalsContact C-N 3.33Å; H532-W534 PolarHBondContact O-N 2.9Å; W534-D536 VanDerWaalsContact C-N 3.31Å; W534-D536 PolarHBondContact O-N 3.39Å; W534-K537 PolarHBondContact O-N 2.85Å; W534-L538 WeakPolarHBondContact O-CB 3.14Å; W534-L538 PolarHBondContact O-N 3.08Å
535	K	62.9	Low	62.6	Low	88 Å²	88	96.6 Å²	96.6	38%	0.383	47%	0.465	S	S	.	.	H	α-helix	trans	-57.4	-44.7	174.6	-169.2	173.5	-174.8	173.8	0	110.9	E170 H531 H532 N539	E170-K535 IonicContact OE1-NZ 3.67Å; E170-K535 PolarHBondContact OE1-NZ 2.7Å; H531-K535 WeakPolarHBondContact O-CB 3.34Å; H531-K535 PolarHBondContact O-N 3.33Å; H532-K535 PolarHBondContact O-N 2.88Å; K535-N539 WeakPolarHBondContact O-CB 3.35Å; K535-N539 PolarHBondContact O-N 2.7Å
536	D	60.6	Low	62.3	Low	35 Å²	35	90.9 Å²	90.9	19%	0.187	44%	0.437	C	S	.	.	H	α-helix	trans	-70.5	-39.9	176.7	-88	-16.1	0	0	0	113.2	H532 H533 W534 N539 R540 R631	H532-D536 WeakPolarHBondContact O-CB 3.33Å; H532-D536 PolarHBondContact O-N 3.03Å; H533-D536 PolarHBondContact O-N 3.36Å; W534-D536 VanDerWaalsContact C-N 3.31Å; W534-D536 PolarHBondContact O-N 3.39Å; D536-N539 PolarHBondContact O-N 3.1Å; D536-R540 WeakPolarHBondContact O-CB 3.43Å; D536-R540 VanDerWaalsContact O-CG 3.3Å; D536-R540 WeakPolarHBondContact O-CG 3.39Å; D536-R540 PolarHBondContact O-N 3.29Å; D536-R631 IonicContact OD1-NH1 2.98Å; D536-R631 IonicContact OD2-CZ 2.82Å; D536-R631 IonicContact OD2-NH1 3.74Å; D536-R631 PolarHBondContact OD2-NH1 3.41Å; D536-R631 IonicContact OD2-NH2 3.72Å; D536-R631 PolarHBondContact OD2-NH2 3Å
537	K	60.8	Low	62.3	Low	104 Å²	104	91 Å²	91	45%	0.452	43%	0.427	S	S	.	.	H	α-helix	trans	-62.9	-43.6	176.9	-169.1	174.4	-176.8	177.8	0	111.2	H533 W534 R540 F541	H533-K537 VanDerWaalsContact O-CB 3.26Å; H533-K537 WeakPolarHBondContact O-CB 3.48Å; H533-K537 PolarHBondContact O-N 2.9Å; W534-K537 PolarHBondContact O-N 2.85Å; K537-R540 PolarHBondContact O-N 3.43Å; K537-F541 WeakPolarHBondContact O-CB 3.22Å; K537-F541 PolarHBondContact O-N 3Å
538	L	62.8	Low	62.6	Low	124 Å²	124	96.6 Å²	96.6	65%	0.649	44%	0.438	S	S	*	.	H	α-helix	trans	-65.7	-40.6	174.4	-173.7	65.2	0	0	0	111.8	W534 F541 N542	W534-L538 WeakPolarHBondContact O-CB 3.14Å; W534-L538 PolarHBondContact O-N 3.08Å; L538-F541 PolarHBondContact O-N 3Å; L538-N542 VanDerWaalsContact O-CB 3.29Å; L538-N542 WeakPolarHBondContact O-CB 3.29Å; L538-N542 PolarHBondContact O-N 2.82Å
539	N	65.5	Low	62.8	Low	72 Å²	72	96.5 Å²	96.5	39%	0.385	43%	0.432	S	S	.	.	H	α-helix	trans	-70	-34.8	178.2	-161.8	6.5	0	0	0	112.2	K535 D536 K543	K535-N539 WeakPolarHBondContact O-CB 3.35Å; K535-N539 PolarHBondContact O-N 2.7Å; D536-N539 PolarHBondContact O-N 3.1Å; N539-K543 WeakPolarHBondContact O-CB 3.26Å; N539-K543 WeakPolarHBondContact O-CG 3.39Å; N539-K543 PolarHBondContact O-N 3.38Å
540	R	65.6	Low	63.4	Low	113 Å²	113	88.5 Å²	88.5	43%	0.426	40%	0.401	S	S	.	.	H	α-helix	trans	-63.9	-49.5	169.1	-75.9	-173.8	-66.3	-113.8	5.2	111	D536 K537 N542 K543 T544	D536-R540 WeakPolarHBondContact O-CB 3.43Å; D536-R540 VanDerWaalsContact O-CG 3.3Å; D536-R540 WeakPolarHBondContact O-CG 3.39Å; D536-R540 PolarHBondContact O-N 3.29Å; K537-R540 PolarHBondContact O-N 3.43Å; R540-N542 VanDerWaalsContact C-N 3.3Å; R540-N542 PolarHBondContact O-N 3.33Å; R540-K543 PolarHBondContact O-N 3.24Å; R540-T544 WeakPolarHBondContact O-CB 3.3Å; R540-T544 PolarHBondContact O-N 2.74Å; R540-T544 PolarHBondContact O-OG1 3.38Å; R540-T544 VanDerWaalsContact O-OG1 3.07Å
541	F	68.3	Low	63.7	Low	111 Å²	111	88 Å²	88	49%	0.487	39%	0.393	S	S	.	.	H	α-helix	trans	-57.3	-44.4	175.6	-179.9	-101	0	0	0	111.7	K537 L538 T544 Y545 V546	K537-F541 WeakPolarHBondContact O-CB 3.22Å; K537-F541 PolarHBondContact O-N 3Å; L538-F541 PolarHBondContact O-N 3Å; F541-T544 PolarHBondContact O-N 2.9Å; F541-Y545 AromaticContact CD2-CD2 3.55Å; F541-Y545 HydrophobicContact CD2-CD2 3.55Å; F541-Y545 HydrophobicContact CD2-CE2 4.13Å; F541-Y545 HydrophobicContact CD2-CG 4.35Å; F541-Y545 AromaticContact CE2-CD2 3.78Å; F541-Y545 HydrophobicContact CE2-CD2 3.78Å; F541-Y545 HydrophobicContact CE2-CE2 4.43Å; F541-Y545 HydrophobicContact CE2-CG 4.17Å; F541-Y545 HydrophobicContact CG-CD2 4.37Å; F541-Y545 PolarHBondContact O-N 2.68Å; F541-V546 HydrophobicContact CD1-CG2 3.69Å; F541-V546 HydrophobicContact CE1-CG2 3.48Å; F541-V546 VanDerWaalsContact CE1-CG2 3.48Å; F541-V546 HydrophobicContact CZ-CG2 4.33Å; F541-V546 PolarHBondContact O-N 3.43Å
542	N	72.4	Confident	63.9	Low	36 Å²	36	83 Å²	83	19%	0.193	37%	0.372	C	S	.	.	I	π-helix	trans	-59.5	-51.5	175.9	-170.1	-9.7	0	0	0	111.4	Y352 L538 R540 T544 V546 K547	Y352-N542 PolarHBondContact OH-ND2 3.46Å; L538-N542 VanDerWaalsContact O-CB 3.29Å; L538-N542 WeakPolarHBondContact O-CB 3.29Å; L538-N542 PolarHBondContact O-N 2.82Å; R540-N542 VanDerWaalsContact C-N 3.3Å; R540-N542 PolarHBondContact O-N 3.33Å; N542-T544 PolarHBondContact O-N 3.31Å; N542-V546 PolarHBondContact O-N 2.9Å; N542-K547 WeakPolarHBondContact O-CB 3.33Å; N542-K547 WeakPolarHBondContact O-CG 3.32Å; N542-K547 PolarHBondContact O-N 3.49Å; N542-K547 WeakPolarHBondContact OD1-CG 3.43Å
543	K	66.8	Low	63.6	Low	121 Å²	121	82.8 Å²	82.8	53%	0.526	39%	0.385	S	S	.	.	I	π-helix	trans	-62.5	-41	178.4	-75.3	-178.2	179	-172.9	0	113.7	N539 R540	N539-K543 WeakPolarHBondContact O-CB 3.26Å; N539-K543 WeakPolarHBondContact O-CG 3.39Å; N539-K543 PolarHBondContact O-N 3.38Å; R540-K543 PolarHBondContact O-N 3.24Å
544	T	62	Low	63.3	Low	80 Å²	80	90.7 Å²	90.7	49%	0.491	42%	0.422	S	S	.	.	I	π-helix	trans	-79	-44.7	-173	-59.7	0	0	0	0	113	R540 F541 N542	R540-T544 WeakPolarHBondContact O-CB 3.3Å; R540-T544 PolarHBondContact O-N 2.74Å; R540-T544 PolarHBondContact O-OG1 3.38Å; R540-T544 VanDerWaalsContact O-OG1 3.07Å; F541-T544 PolarHBondContact O-N 2.9Å; N542-T544 PolarHBondContact O-N 3.31Å
545	Y	64.8	Low	62.8	Low	152 Å²	152	89.1 Å²	89.1	60%	0.596	42%	0.416	S	S	*	.	I	π-helix	trans	-108.6	-59.7	-172.7	-60.8	-82.8	0	0	0	111.5	F541 K548 W549	F541-Y545 AromaticContact CD2-CD2 3.55Å; F541-Y545 HydrophobicContact CD2-CD2 3.55Å; F541-Y545 HydrophobicContact CD2-CE2 4.13Å; F541-Y545 HydrophobicContact CD2-CG 4.35Å; F541-Y545 AromaticContact CE2-CD2 3.78Å; F541-Y545 HydrophobicContact CE2-CD2 3.78Å; F541-Y545 HydrophobicContact CE2-CE2 4.43Å; F541-Y545 HydrophobicContact CE2-CG 4.17Å; F541-Y545 HydrophobicContact CG-CD2 4.37Å; F541-Y545 PolarHBondContact O-N 2.68Å; Y545-K548 PolarHBondContact O-N 3.34Å; Y545-W549 WeakPolarHBondContact O-CB 3.38Å; Y545-W549 PolarHBondContact O-N 2.85Å
546	V	65.4	Low	61.8	Low	28 Å²	28	88.1 Å²	88.1	17%	0.17	42%	0.42	C	S	.	.	I	π-helix	trans	-63.5	-51.7	-167.8	-171	0	0	0	0	111	Y352 F541 N542 K548 W549 L550	Y352-V546 HydrophobicContact CE1-CG1 3.64Å; Y352-V546 HydrophobicContact CE2-CG1 4.36Å; Y352-V546 WeakPolarHBondContact OH-CG1 3.44Å; F541-V546 HydrophobicContact CD1-CG2 3.69Å; F541-V546 HydrophobicContact CE1-CG2 3.48Å; F541-V546 VanDerWaalsContact CE1-CG2 3.48Å; F541-V546 HydrophobicContact CZ-CG2 4.33Å; F541-V546 PolarHBondContact O-N 3.43Å; N542-V546 PolarHBondContact O-N 2.9Å; V546-K548 PolarHBondContact O-N 3.14Å; V546-W549 PolarHBondContact O-N 3.2Å; V546-L550 HydrophobicContact CB-CD1 4.47Å; V546-L550 HydrophobicContact CG1-CD1 3.39Å; V546-L550 WeakPolarHBondContact O-CB 3.48Å; V546-L550 PolarHBondContact O-N 2.63Å
547	K	68.3	Low	60.9	Low	88 Å²	88	89 Å²	89	38%	0.383	43%	0.429	S	S	.	.	H	α-helix	trans	-61.8	-39.8	176	-71.8	-160	175	-160.3	0	113.4	N542 W549 I551	N542-K547 WeakPolarHBondContact O-CB 3.33Å; N542-K547 WeakPolarHBondContact O-CG 3.32Å; N542-K547 PolarHBondContact O-N 3.49Å; N542-K547 WeakPolarHBondContact OD1-CG 3.43Å; K547-W549 VanDerWaalsContact C-N 3.26Å; K547-W549 PolarHBondContact O-N 2.97Å; K547-I551 HydrophobicContact CB-CD1 3.89Å; K547-I551 HydrophobicContact CB-CG1 4.41Å; K547-I551 HydrophobicContact CD-CD1 3.9Å; K547-I551 HydrophobicContact CG-CD1 3.82Å; K547-I551 VanDerWaalsContact O-CB 3.23Å; K547-I551 WeakPolarHBondContact O-CB 3.04Å; K547-I551 WeakPolarHBondContact O-CG1 3.5Å; K547-I551 PolarHBondContact O-N 3.11Å
548	K	64.9	Low	60.2	Low	167 Å²	167	91.1 Å²	91.1	73%	0.726	44%	0.44	S	S	*	.	H	α-helix	trans	-68.3	-29.6	-179	-167.4	177.4	-179.8	-175.8	0	112.1	R307 Y545 V546	R307-K548 PolarHBondContact NH1-O 2.85Å; Y545-K548 PolarHBondContact O-N 3.34Å; V546-K548 PolarHBondContact O-N 3.14Å
549	W	67.7	Low	59.4	Low	148 Å²	148	89.1 Å²	89.1	56%	0.561	44%	0.435	S	S	*	.	H	α-helix	trans	-88	-39.1	178.8	-165.1	56	0	0	0	113	V300 F304 R307 Y545 V546 K547	V300-W549 HydrophobicContact CG1-CZ3 3.92Å; F304-W549 HydrophobicContact CD2-CH2 4.44Å; F304-W549 HydrophobicContact CD2-CZ2 4.15Å; F304-W549 HydrophobicContact CE2-CZ2 4.05Å; R307-W549 PolarHBondContact NH1-O 3.02Å; Y545-W549 WeakPolarHBondContact O-CB 3.38Å; Y545-W549 PolarHBondContact O-N 2.85Å; V546-W549 PolarHBondContact O-N 3.2Å; K547-W549 VanDerWaalsContact C-N 3.26Å; K547-W549 PolarHBondContact O-N 2.97Å
550	L	67.9	Low	58.5	Low	2 Å²	2	91.9 Å²	91.9	1%	0.01	45%	0.445	C	S	.	.	H	α-helix	trans	-94.4	-25	-174	-70.2	151.7	0	0	0	114.3	V300 A303 F304 Y352 N356 V546	V300-L550 HydrophobicContact CG1-CD2 4.37Å; A303-L550 HydrophobicContact CB-CD2 3.75Å; F304-L550 HydrophobicContact CB-CD2 3.85Å; Y352-L550 HydrophobicContact CD1-CB 4.29Å; Y352-L550 HydrophobicContact CD1-CD1 4.43Å; Y352-L550 HydrophobicContact CD2-CD1 4.46Å; Y352-L550 HydrophobicContact CG-CB 4.39Å; Y352-L550 HydrophobicContact CG-CD1 4.42Å; N356-L550 PolarHBondContact ND2-O 3.37Å; V546-L550 HydrophobicContact CB-CD1 4.47Å; V546-L550 HydrophobicContact CG1-CD1 3.39Å; V546-L550 WeakPolarHBondContact O-CB 3.48Å; V546-L550 PolarHBondContact O-N 2.63Å
551	I	66.8	Low	57.6	Low	10 Å²	10	93.4 Å²	93.4	5%	0.051	46%	0.462	C	S	.	.	S	Bend	trans	-91.6	135	179.9	-54.4	178.7	0	0	0	110.9	A355 N356 K547 G553	A355-I551 HydrophobicContact CB-CD1 4.13Å; A355-I551 HydrophobicContact CB-CG1 4.41Å; N356-I551 VanDerWaalsContact OD1-CA 3.29Å; N356-I551 WeakPolarHBondContact OD1-CA 3.48Å; K547-I551 HydrophobicContact CB-CD1 3.89Å; K547-I551 HydrophobicContact CB-CG1 4.41Å; K547-I551 HydrophobicContact CD-CD1 3.9Å; K547-I551 HydrophobicContact CG-CD1 3.82Å; K547-I551 VanDerWaalsContact O-CB 3.23Å; K547-I551 WeakPolarHBondContact O-CB 3.04Å; K547-I551 WeakPolarHBondContact O-CG1 3.5Å; K547-I551 PolarHBondContact O-N 3.11Å; I551-G553 PolarHBondContact O-N 3.48Å
552	A	56.5	Low	56.6	Low	18 Å²	18	91.4 Å²	91.4	15%	0.149	46%	0.455	C	S	.	.			trans	-62	132.8	173.3	0	0	0	0	0	111.2	R307 N356 E554 R555 S556	R307-A552 HydrophobicContact CG-CB 4.06Å; N356-A552 PolarHBondContact OD1-N 2.92Å; A552-E554 VanDerWaalsContact C-N 3.29Å; A552-E554 PolarHBondContact O-N 2.86Å; A552-R555 PolarHBondContact O-N 3.23Å; A552-S556 PolarHBondContact O-N 3.44Å
553	G	50.3	Low	55.5	Low	50 Å²	50	92 Å²	92	52%	0.515	46%	0.462	S	S	.	.	H	α-helix	trans	-51.4	-40.1	-162	0	0	0	0	0	115.5	I551 R555 S556	I551-G553 PolarHBondContact O-N 3.48Å; G553-R555 PolarHBondContact O-N 2.93Å; G553-S556 PolarHBondContact O-N 3.39Å; G553-S556 PolarHBondContact O-OG 2.78Å
554	E	50.5	Low	54.7	Low	195 Å²	195	92.6 Å²	92.6	91%	0.911	47%	0.465	S	S	*	.	H	α-helix	trans	-72.5	-25	-176.5	-62.4	-176.3	148.1	0	0	114.4	A552	A552-E554 VanDerWaalsContact C-N 3.29Å; A552-E554 PolarHBondContact O-N 2.86Å
555	R	47.8	Very low	54.3	Low	130 Å²	130	94.7 Å²	94.7	49%	0.491	47%	0.465	S	S	.	.	H	α-helix	trans	-97.2	-1.5	175.2	-67.5	-171	-171.9	150.6	15.9	113.7	N356 I357 A552 G553	N356-R555 PolarHBondContact O-NH1 2.96Å; I357-R555 PolarHBondContact O-NH1 2.97Å; A552-R555 PolarHBondContact O-N 3.23Å; G553-R555 PolarHBondContact O-N 2.93Å
556	S	41.5	Very low	53.6	Low	67 Å²	67	89.2 Å²	89.2	47%	0.469	45%	0.446	S	S	.	.	H	α-helix	trans	-76.7	-26.5	-178.6	73.9	0	0	0	0	113.6	A552 G553	A552-S556 PolarHBondContact O-N 3.44Å; G553-S556 PolarHBondContact O-N 3.39Å; G553-S556 PolarHBondContact O-OG 2.78Å
557	S	42.8	Very low	53.4	Low	52 Å²	52	94.7 Å²	94.7	36%	0.364	47%	0.467	S	S	.	.	S	Bend	trans	-66.6	133.3	160.6	-72.8	0	0	0	0	108.6	Q560	S557-Q560 PolarHBondContact OG-NE2 2.82Å
558	E	45.6	Very low	53.3	Low	149 Å²	149	95 Å²	95	70%	0.696	47%	0.471	S	S	*	.			trans	-44.1	138.7	157.9	-65.1	-176.5	148.7	0	0	108.6	Q560	E558-Q560 WeakPolarHBondContact O-CA 3.45Å; E558-Q560 PolarHBondContact O-N 3.39Å
559	P	46.1	Very low	53.1	Low	82 Å²	82	89.4 Å²	89.4	53%	0.532	45%	0.447	S	S	.	.			trans	-48.8	106.2	-174.1	17.6	-31.9	0	0	0	108.7	L561 I562	P559-L561 PolarHBondContact O-N 3.49Å; P559-I562 HydrophobicContact CB-CD1 4.37Å; P559-I562 HydrophobicContact CG-CB 4.27Å; P559-I562 HydrophobicContact CG-CD1 3.76Å; P559-I562 HydrophobicContact CG-CG1 4.44Å; P559-I562 WeakPolarHBondContact O-CB 3.37Å; P559-I562 PolarHBondContact O-N 2.87Å
560	Q	46.9	Very low	52.4	Low	130 Å²	130	86.2 Å²	86.2	61%	0.607	44%	0.44	S	S	*	.	H	α-helix	trans	-62.2	-28.5	-160.6	-68.2	-177.6	-5	0	0	110.2	S557 E558 I562 S563 F564	S557-Q560 PolarHBondContact OG-NE2 2.82Å; E558-Q560 WeakPolarHBondContact O-CA 3.45Å; E558-Q560 PolarHBondContact O-N 3.39Å; Q560-I562 VanDerWaalsContact C-N 3.31Å; Q560-I562 PolarHBondContact O-N 3.18Å; Q560-S563 PolarHBondContact O-N 3.38Å; Q560-S563 PolarHBondContact O-OG 2.9Å; Q560-F564 WeakPolarHBondContact O-CA 3.47Å; Q560-F564 WeakPolarHBondContact O-CB 3.32Å; Q560-F564 PolarHBondContact O-N 2.78Å
561	L	46.3	Very low	52.3	Low	146 Å²	146	93 Å²	93	76%	0.764	47%	0.469	S	S	*	.	H	α-helix	trans	-51.1	-41.4	169.4	-162.9	69.9	0	0	0	114.1	P559 Y565	P559-L561 PolarHBondContact O-N 3.49Å; L561-Y565 WeakPolarHBondContact O-CB 3.28Å; L561-Y565 PolarHBondContact O-N 2.98Å
562	I	47.6	Very low	51.8	Low	68 Å²	68	97.4 Å²	97.4	35%	0.349	49%	0.49	S	S	.	.	H	α-helix	trans	-74.1	-44.9	179.9	-82	164.2	0	0	0	111.7	P559 Q560 F564 Y565 N566	P559-I562 HydrophobicContact CB-CD1 4.37Å; P559-I562 HydrophobicContact CG-CB 4.27Å; P559-I562 HydrophobicContact CG-CD1 3.76Å; P559-I562 HydrophobicContact CG-CG1 4.44Å; P559-I562 WeakPolarHBondContact O-CB 3.37Å; P559-I562 PolarHBondContact O-N 2.87Å; Q560-I562 VanDerWaalsContact C-N 3.31Å; Q560-I562 PolarHBondContact O-N 3.18Å; I562-F564 VanDerWaalsContact C-N 3.32Å; I562-Y565 PolarHBondContact O-N 2.85Å; I562-N566 WeakPolarHBondContact O-CB 3.22Å; I562-N566 PolarHBondContact O-N 3.09Å; I562-N566 PolarHBondContact O-ND2 3.28Å
563	S	49.8	Very low	51.7	Low	48 Å²	48	99 Å²	99	34%	0.336	50%	0.503	S	S	.	.	H	α-helix	trans	-71.1	-32.4	178.2	57.1	0	0	0	0	111.2	Q560 K567	Q560-S563 PolarHBondContact O-N 3.38Å; Q560-S563 PolarHBondContact O-OG 2.9Å; S563-K567 WeakPolarHBondContact O-CB 3.46Å; S563-K567 PolarHBondContact O-N 3.22Å
564	F	50.2	Low	51.9	Low	134 Å²	134	102.6 Å²	102.6	59%	0.588	51%	0.508	S	S	*	.	H	α-helix	trans	-71.2	-40.9	172.5	-160.4	-83.8	0	0	0	112	Q560 I562 K567 M568	Q560-F564 WeakPolarHBondContact O-CA 3.47Å; Q560-F564 WeakPolarHBondContact O-CB 3.32Å; Q560-F564 PolarHBondContact O-N 2.78Å; I562-F564 VanDerWaalsContact C-N 3.32Å; F564-K567 CarbonylContact O-C 3.48Å; F564-K567 PolarHBondContact O-N 3.24Å; F564-M568 HydrophobicContact CD1-CG 4.25Å; F564-M568 HydrophobicContact CD1-SD 4.09Å; F564-M568 HydrophobicContact CE1-CG 4.18Å; F564-M568 HydrophobicContact CE1-SD 3.9Å; F564-M568 WeakPolarHBondContact O-CB 3.43Å; F564-M568 PolarHBondContact O-N 3.01Å
565	Y	53.9	Low	52.3	Low	125 Å²	125	98.5 Å²	98.5	49%	0.49	49%	0.49	S	S	.	.	H	α-helix	trans	-62.1	-50.6	173.5	-172.8	-87.6	0	0	0	111	L561 I562 K567 M568 E569	L561-Y565 WeakPolarHBondContact O-CB 3.28Å; L561-Y565 PolarHBondContact O-N 2.98Å; I562-Y565 PolarHBondContact O-N 2.85Å; Y565-K567 PolarHBondContact O-N 3.19Å; Y565-M568 WeakPolarHBondContact O-CB 3.24Å; Y565-M568 PolarHBondContact O-N 3.41Å; Y565-M568 VanDerWaalsContact O-N 3.09Å; Y565-E569 HydrophobicContact CD1-CG 4.14Å; Y565-E569 HydrophobicContact CE1-CG 3.67Å; Y565-E569 WeakPolarHBondContact CE1-OE1 3.33Å; Y565-E569 PolarHBondContact O-N 3.43Å; Y565-E569 PolarHBondContact OH-OE1 2.84Å
566	N	49.5	Very low	52.9	Low	37 Å²	37	97.3 Å²	97.3	20%	0.198	49%	0.493	C	S	.	.	H	α-helix	trans	-58.7	-35.2	174.3	-68.2	-14.4	0	0	0	112.2	I562 M570	I562-N566 WeakPolarHBondContact O-CB 3.22Å; I562-N566 PolarHBondContact O-N 3.09Å; I562-N566 PolarHBondContact O-ND2 3.28Å; N566-M570 VanDerWaalsContact O-CB 3.27Å; N566-M570 WeakPolarHBondContact O-CB 3.4Å; N566-M570 PolarHBondContact O-N 3.48Å
567	K	60.9	Low	53.9	Low	143 Å²	143	99.7 Å²	99.7	62%	0.622	50%	0.504	S	S	*	.	H	α-helix	trans	-75.5	-30.5	177.4	-169.1	174.7	-173.3	178	0	112.6	S563 F564 Y565 K571	S563-K567 WeakPolarHBondContact O-CB 3.46Å; S563-K567 PolarHBondContact O-N 3.22Å; F564-K567 CarbonylContact O-C 3.48Å; F564-K567 PolarHBondContact O-N 3.24Å; Y565-K567 PolarHBondContact O-N 3.19Å; K567-K571 WeakPolarHBondContact O-CB 3.36Å; K567-K571 PolarHBondContact O-N 3.5Å
568	M	66.5	Low	54.4	Low	93 Å²	93	104.7 Å²	104.7	46%	0.458	52%	0.522	S	S	.	.	H	α-helix	trans	-69.1	-50.8	169.8	-96.2	-176	55.6	0	0	111.1	F564 Y565 M570 K571 Q572	F564-M568 HydrophobicContact CD1-CG 4.25Å; F564-M568 HydrophobicContact CD1-SD 4.09Å; F564-M568 HydrophobicContact CE1-CG 4.18Å; F564-M568 HydrophobicContact CE1-SD 3.9Å; F564-M568 WeakPolarHBondContact O-CB 3.43Å; F564-M568 PolarHBondContact O-N 3.01Å; Y565-M568 WeakPolarHBondContact O-CB 3.24Å; Y565-M568 PolarHBondContact O-N 3.41Å; Y565-M568 VanDerWaalsContact O-N 3.09Å; M568-M570 VanDerWaalsContact C-N 3.34Å; M568-M570 PolarHBondContact O-N 3.43Å; M568-K571 CarbonylContact O-C 3.55Å; M568-K571 WeakPolarHBondContact O-CB 3.15Å; M568-K571 PolarHBondContact O-N 3.37Å; M568-K571 VanDerWaalsContact O-N 3.14Å; M568-Q572 PolarHBondContact O-N 3Å
569	E	59.3	Low	54.8	Low	50 Å²	50	101.1 Å²	101.1	23%	0.234	51%	0.514	C	S	.	.	H	α-helix	trans	-62.9	-40.7	178.2	-74.2	-158.8	157	0	0	111.6	Y565 K571 Q572 A573	Y565-E569 HydrophobicContact CD1-CG 4.14Å; Y565-E569 HydrophobicContact CE1-CG 3.67Å; Y565-E569 WeakPolarHBondContact CE1-OE1 3.33Å; Y565-E569 PolarHBondContact O-N 3.43Å; Y565-E569 PolarHBondContact OH-OE1 2.84Å; E569-K571 VanDerWaalsContact C-N 3.33Å; E569-K571 PolarHBondContact O-N 3.3Å; E569-Q572 PolarHBondContact O-N 3.03Å; E569-A573 WeakPolarHBondContact O-CB 3.48Å; E569-A573 PolarHBondContact O-N 2.91Å
570	M	54.4	Low	54.8	Low	82 Å²	82	99.7 Å²	99.7	40%	0.404	51%	0.513	S	S	.	.	H	α-helix	trans	-68.8	-31.9	175.1	-168.4	157.8	67.8	0	0	112.5	N566 M568 M574 N626	N566-M570 VanDerWaalsContact O-CB 3.27Å; N566-M570 WeakPolarHBondContact O-CB 3.4Å; N566-M570 PolarHBondContact O-N 3.48Å; M568-M570 VanDerWaalsContact C-N 3.34Å; M568-M570 PolarHBondContact O-N 3.43Å; M570-M574 WeakPolarHBondContact O-CB 3.44Å; M570-M574 PolarHBondContact O-N 2.9Å; M570-N626 VanDerWaalsContact CE-OD1 3.3Å; M570-N626 WeakPolarHBondContact CE-OD1 3.44Å; M570-N626 PolarHBondContact SD-ND2 2.61Å; M570-N626 PolarHBondContact SD-OD1 3.08Å
571	K	64.4	Low	54.7	Low	143 Å²	143	97 Å²	97	62%	0.622	51%	0.509	S	S	*	.	H	α-helix	trans	-66	-41.1	168.4	-97.1	-165	167.6	-163.6	0	112.2	K567 M568 E569 M574 M575	K567-K571 WeakPolarHBondContact O-CB 3.36Å; K567-K571 PolarHBondContact O-N 3.5Å; M568-K571 CarbonylContact O-C 3.55Å; M568-K571 WeakPolarHBondContact O-CB 3.15Å; M568-K571 PolarHBondContact O-N 3.37Å; M568-K571 VanDerWaalsContact O-N 3.14Å; E569-K571 VanDerWaalsContact C-N 3.33Å; E569-K571 PolarHBondContact O-N 3.3Å; K571-M574 PolarHBondContact O-N 3.04Å; K571-M575 HydrophobicContact CB-CE 4.41Å; K571-M575 WeakPolarHBondContact O-CB 3.33Å; K571-M575 WeakPolarHBondContact O-CE 3.19Å; K571-M575 WeakPolarHBondContact O-CG 3.45Å; K571-M575 PolarHBondContact O-N 2.79Å
572	Q	57.6	Low	54.5	Low	104 Å²	104	94.8 Å²	94.8	49%	0.486	51%	0.512	S	S	.	.	H	α-helix	trans	-66.4	-43.7	176.5	-78.6	-178.2	-23.7	0	0	111.4	M568 E569 M575 L576	M568-Q572 PolarHBondContact O-N 3Å; E569-Q572 PolarHBondContact O-N 3.03Å; Q572-M575 PolarHBondContact O-N 3.38Å; Q572-L576 WeakPolarHBondContact O-CB 3.4Å; Q572-L576 VanDerWaalsContact O-CG 3.29Å; Q572-L576 WeakPolarHBondContact O-CG 3.38Å; Q572-L576 PolarHBondContact O-N 3.38Å
573	A	55	Low	54	Low	52 Å²	52	95.9 Å²	95.9	43%	0.43	53%	0.531	S	S	.	.	H	α-helix	trans	-62.3	-43.1	174.8	0	0	0	0	0	111.6	E569 L576 V577	E569-A573 WeakPolarHBondContact O-CB 3.48Å; E569-A573 PolarHBondContact O-N 2.91Å; A573-L576 PolarHBondContact O-N 3.39Å; A573-V577 WeakPolarHBondContact O-CG2 3.34Å; A573-V577 PolarHBondContact O-N 3.44Å
574	M	52.8	Low	53.3	Low	125 Å²	125	102.7 Å²	102.7	62%	0.616	55%	0.554	S	S	*	*	H	α-helix	trans	-63.8	-45.9	174.9	-175.1	166.2	-91	0	0	111.4	M570 K571 L576 V577 E578	M570-M574 WeakPolarHBondContact O-CB 3.44Å; M570-M574 PolarHBondContact O-N 2.9Å; K571-M574 PolarHBondContact O-N 3.04Å; M574-L576 VanDerWaalsContact C-N 3.33Å; M574-L576 PolarHBondContact O-N 3.49Å; M574-V577 PolarHBondContact O-N 3.11Å; M574-E578 VanDerWaalsContact O-CB 3.23Å; M574-E578 WeakPolarHBondContact O-CB 3.49Å; M574-E578 PolarHBondContact O-N 3.02Å
575	M	59.4	Low	52.3	Low	108 Å²	108	104 Å²	104	53%	0.532	57%	0.567	S	S	.	*	H	α-helix	trans	-64.3	-32	173.9	-75.4	-174.4	-67.7	0	0	113.3	K571 Q572 S579	K571-M575 HydrophobicContact CB-CE 4.41Å; K571-M575 WeakPolarHBondContact O-CB 3.33Å; K571-M575 WeakPolarHBondContact O-CE 3.19Å; K571-M575 WeakPolarHBondContact O-CG 3.45Å; K571-M575 PolarHBondContact O-N 2.79Å; Q572-M575 PolarHBondContact O-N 3.38Å; M575-S579 WeakPolarHBondContact O-CB 3.42Å; M575-S579 PolarHBondContact O-N 2.72Å; M575-S579 PolarHBondContact O-OG 3.25Å
576	L	60.4	Low	51.2	Low	105 Å²	105	103.5 Å²	103.5	55%	0.55	58%	0.579	S	S	.	*	H	α-helix	trans	-69.1	-33.8	174.6	-82.3	163.1	0	0	0	112.5	Q572 A573 M574 S581	Q572-L576 WeakPolarHBondContact O-CB 3.4Å; Q572-L576 VanDerWaalsContact O-CG 3.29Å; Q572-L576 WeakPolarHBondContact O-CG 3.38Å; Q572-L576 PolarHBondContact O-N 3.38Å; A573-L576 PolarHBondContact O-N 3.39Å; M574-L576 VanDerWaalsContact C-N 3.33Å; M574-L576 PolarHBondContact O-N 3.49Å; L576-S581 PolarHBondContact O-N 3.28Å
577	V	61.6	Low	50.2	Low	118 Å²	118	107 Å²	107	72%	0.715	61%	0.606	S	S	*	*	H	α-helix	trans	-74.5	-45.2	173.1	171.3	0	0	0	0	110.7	A573 M574 G580	A573-V577 WeakPolarHBondContact O-CG2 3.34Å; A573-V577 PolarHBondContact O-N 3.44Å; M574-V577 PolarHBondContact O-N 3.11Å; V577-G580 PolarHBondContact O-N 3.22Å
578	E	55.2	Low	48.9	Very low	156 Å²	156	106.3 Å²	106.3	73%	0.729	61%	0.613	S	S	*	*	H	α-helix	trans	-71	-31.5	-177.7	-168.6	169.3	-159.3	0	0	112.9	M574 G580	M574-E578 VanDerWaalsContact O-CB 3.23Å; M574-E578 WeakPolarHBondContact O-CB 3.49Å; M574-E578 PolarHBondContact O-N 3.02Å; E578-G580 VanDerWaalsContact C-N 3.26Å; E578-G580 PolarHBondContact O-N 3.46Å
579	S	52.5	Low	47	Very low	75 Å²	75	107.2 Å²	107.2	52%	0.524	63%	0.629	S	S	.	*	T	Hydrogen-bonded Turn	trans	-81	5	172.8	63.5	0	0	0	0	114.6	M575 S581	M575-S579 WeakPolarHBondContact O-CB 3.42Å; M575-S579 PolarHBondContact O-N 2.72Å; M575-S579 PolarHBondContact O-OG 3.25Å; S579-S581 PolarHBondContact O-N 2.93Å
580	G	45.7	Very low	45.7	Very low	51 Å²	51	114 Å²	114	53%	0.526	66%	0.658	S	S	.	*	T	Hydrogen-bonded Turn	trans	63.2	9.9	175.3	0	0	0	0	0	115.8	V577 E578 A582	V577-G580 PolarHBondContact O-N 3.22Å; E578-G580 VanDerWaalsContact C-N 3.26Å; E578-G580 PolarHBondContact O-N 3.46Å; G580-A582 PolarHBondContact O-N 3.46Å
581	S	46.2	Very low	44.4	Very low	75 Å²	75	119.9 Å²	119.9	52%	0.524	68%	0.681	S	S	.	*	G	3₁₀ helix	trans	-75.4	5.4	-171.2	-72.4	0	0	0	0	114.8	L576 S579 A583	L576-S581 PolarHBondContact O-N 3.28Å; S579-S581 PolarHBondContact O-N 2.93Å; S581-A583 PolarHBondContact O-N 2.91Å; S581-A583 VanDerWaalsContact O-N 3.15Å
582	A	41.2	Very low	42.7	Very low	99 Å²	99	119.8 Å²	119.8	82%	0.818	69%	0.692	S	S	*	*	G	3₁₀ helix	trans	-63	-12.6	170.2	0	0	0	0	0	114	G580	G580-A582 PolarHBondContact O-N 3.46Å
583	A	37	Very low	41.3	Very low	90 Å²	90	123.8 Å²	123.8	74%	0.744	71%	0.708	S	S	*	*	G	3₁₀ helix	trans	-90.6	-2.2	-175.5	0	0	0	0	0	116	S581	S581-A583 PolarHBondContact O-N 2.91Å; S581-A583 VanDerWaalsContact O-N 3.15Å
584	K	34.9	Very low	40	Very low	191 Å²	191	132.6 Å²	132.6	83%	0.83	73%	0.73	S	S	*	*			trans	-136.5	82.3	179.9	-73.7	-174.3	179.5	174.6	0	113.7
585	L	30.1	Very low	38.7	Very low	162 Å²	162	133.1 Å²	133.1	85%	0.848	74%	0.74	S	S	*	*			trans	-67.6	137.2	151.8	-83.2	146.4	0	0	0	109.1	S587	L585-S587 PolarHBondContact O-N 3.43Å
586	P	31.2	Very low	37.1	Very low	115 Å²	115	132 Å²	132	75%	0.747	75%	0.749	S	S	*	*			trans	-70.1	118.3	178	27.5	-33	0	0	0	110.6	V588	P586-V588 PolarHBondContact O-N 2.95Å; P586-V588 VanDerWaalsContact O-N 3.11Å
587	S	28.8	Very low	35.4	Very low	109 Å²	109	136.2 Å²	136.2	76%	0.762	77%	0.765	S	S	*	*			trans	-70.1	102.5	172.4	41.6	0	0	0	0	110.4	L585 S589	L585-S587 PolarHBondContact O-N 3.43Å; S587-S589 PolarHBondContact O-N 2.9Å
588	V	32.3	Very low	33.7	Very low	129 Å²	129	138.7 Å²	138.7	78%	0.782	77%	0.769	S	S	*	*			trans	-65.1	101.9	172.4	177.1	0	0	0	0	109	P586 K590	P586-V588 PolarHBondContact O-N 2.95Å; P586-V588 VanDerWaalsContact O-N 3.11Å; V588-K590 PolarHBondContact O-N 2.91Å
589	S	27.6	Very low	32.2	Very low	113 Å²	113	139.3 Å²	139.3	79%	0.79	77%	0.772	S	S	*	*			trans	-63.7	112.1	178.4	-66.7	0	0	0	0	111.5	S587	S587-S589 PolarHBondContact O-N 2.9Å
590	K	30.5	Very low	30.9	Very low	193 Å²	193	141.3 Å²	141.3	84%	0.839	79%	0.786	S	S	*	*			trans	-101.1	105.5	163.3	-79.3	-171.6	174.6	-177.7	0	110.5	V588	V588-K590 PolarHBondContact O-N 2.91Å
591	K	28.8	Very low	29.8	Very low	205 Å²	205	147.2 Å²	147.2	89%	0.891	80%	0.8	S	S	*	*			trans	-78.8	115.2	163.2	-78.2	178.1	174.7	174.2	0	109.4
592	V	26.8	Very low	29	Very low	140 Å²	140	149.4 Å²	149.4	85%	0.848	81%	0.812	S	S	*	*			trans	-140.9	139.3	153.9	-176.3	0	0	0	0	107.7
593	K	28.2	Very low	28.6	Very low	189 Å²	189	150.8 Å²	150.8	82%	0.822	81%	0.811	S	S	*	*			trans	-103.6	137.2	-178.6	-73.1	178.3	175.3	177.2	0	110.9
594	R	28.1	Very low	28.4	Very low	236 Å²	236	152.3 Å²	152.3	89%	0.891	81%	0.813	S	S	*	*			trans	56.5	147.1	151.3	-60.4	180	175.2	172.7	-3.8	115.9
595	T	25.2	Very low	28.1	Very low	136 Å²	136	152 Å²	152	83%	0.834	82%	0.815	S	S	*	*			cis	-145.3	171.9	34.9	-57.8	0	0	0	0	110.6
596	A	27	Very low	28.3	Very low	86 Å²	86	156 Å²	156	71%	0.711	82%	0.818	S	S	*	*			trans	-75.1	150.5	-179.1	0	0	0	0	0	114
597	E	25	Very low	28.3	Very low	192 Å²	192	159.2 Å²	159.2	90%	0.897	83%	0.826	S	S	*	*				-172.6	-176.5	122.3	-104.3	174.5	173.3	0	0	111.6
598	Q	25.4	Very low	28.7	Very low	171 Å²	171	161.2 Å²	161.2	80%	0.799	83%	0.827	S	S	*	*			trans	-92.9	170.8	-151.8	-57.8	170.4	-51.4	0	0	116.9
599	Q	24.1	Very low	29.3	Very low	169 Å²	169	160.4 Å²	160.4	79%	0.79	82%	0.824	S	S	*	*			trans	101.9	122.3	147.1	-75.5	170.9	10.6	0	0	122.2
600	S	23.9	Very low	30	Very low	117 Å²	117	164.9 Å²	164.9	82%	0.818	83%	0.829	S	S	*	*			trans	67.1	130.3	150.8	47.3	0	0	0	0	122.1
601	E	24.1	Very low	31.1	Very low	174 Å²	174	160 Å²	160	81%	0.813	81%	0.811	S	S	*	*			trans	-66.6	161	168.5	-51.8	-173.5	122.3	0	0	112.4
602	P	28.1	Very low	32.7	Very low	121 Å²	121	153.4 Å²	153.4	79%	0.786	79%	0.791	S	S	*	*				-135	162.1	82.5	29.2	-11.8	0	0	0	115
603	T	32.9	Very low	34	Very low	129 Å²	129	155.5 Å²	155.5	79%	0.791	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-64	128.6	177.1	19.7	0	0	0	0	113.5
604	P	33.1	Very low	35.1	Very low	122 Å²	122	152 Å²	152	79%	0.792	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-94.2	137.9	167.4	33.8	-29.7	0	0	0	112.1
605	E	29.7	Very low	36.3	Very low	183 Å²	183	148.2 Å²	148.2	86%	0.855	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-59.7	149.9	179.1	-60.8	176.4	119.8	0	0	113.4	M607	E605-M607 PolarHBondContact O-N 2.92Å
606	R	32.8	Very low	37.9	Very low	246 Å²	246	144.4 Å²	144.4	93%	0.928	74%	0.741	S	S	*	*			trans	-63.9	94.8	170.4	-86	-178.9	169.6	167.5	-2.7	110.9	I608	R606-I608 PolarHBondContact O-N 3.1Å
607	M	31.6	Very low	39.4	Very low	183 Å²	183	143 Å²	143	90%	0.901	73%	0.73	S	S	*	*			trans	-64.6	105.7	164.4	-96.4	-176.6	-106.3	0	0	110.6	E605	E605-M607 PolarHBondContact O-N 2.92Å
608	I	38	Very low	41.1	Very low	152 Å²	152	138 Å²	138	78%	0.779	71%	0.706	S	S	*	*			trans	-63.6	126.6	167	-57.9	173.4	0	0	0	107.7	R606 K610	R606-I608 PolarHBondContact O-N 3.1Å; I608-K610 PolarHBondContact O-N 2.98Å
609	P	43.6	Very low	42.8	Very low	111 Å²	111	133.2 Å²	133.2	72%	0.721	69%	0.686	S	S	*	*			trans	-65.2	119.6	-179.2	25.2	-33.1	0	0	0	110.4	I611	P609-I611 PolarHBondContact O-N 3.38Å; P609-I611 VanDerWaalsContact O-N 3.1Å
610	K	43.6	Very low	44.2	Very low	208 Å²	208	127.5 Å²	127.5	90%	0.904	66%	0.657	S	S	*	*			trans	-63.6	111.5	175.7	-70.1	176.5	-179.5	170.5	0	109.4	I608	I608-K610 PolarHBondContact O-N 2.98Å
611	I	54.1	Low	45.9	Very low	91 Å²	91	127.9 Å²	127.9	47%	0.467	64%	0.64	S	S	.	*			trans	-64.1	139.8	176.5	-56	176.5	0	0	0	108.4	P609 R615 E616	P609-I611 PolarHBondContact O-N 3.38Å; P609-I611 VanDerWaalsContact O-N 3.1Å; I611-R615 HydrophobicContact CG2-CB 3.95Å; I611-R615 HydrophobicContact CG2-CG 4.26Å; I611-E616 HydrophobicContact CB-CG 3.98Å; I611-E616 HydrophobicContact CG2-CG 3.71Å
612	S	61	Low	47.6	Very low	65 Å²	65	122.4 Å²	122.4	46%	0.455	62%	0.616	S	S	.	*			trans	-68.2	141.8	176.5	71.7	0	0	0	0	110.3	T614 R615 E616	S612-T614 PolarHBondContact O-N 3.27Å; S612-R615 PolarHBondContact O-N 3.3Å; S612-R615 WeakPolarHBondContact OG-CB 3.42Å; S612-R615 PolarHBondContact OG-N 2.85Å; S612-E616 PolarHBondContact O-N 2.99Å
613	K	54.4	Low	48.9	Very low	185 Å²	185	120 Å²	120	80%	0.804	60%	0.596	S	S	*	*	H	α-helix	trans	-53.2	-32.3	-178.9	-68.4	178.9	178.3	175	0	112.9	A617	K613-A617 PolarHBondContact O-N 3.47Å; K613-A617 VanDerWaalsContact O-N 3.11Å
614	T	51.8	Low	49.9	Very low	114 Å²	114	118.2 Å²	118.2	70%	0.699	58%	0.575	S	S	*	*	H	α-helix	trans	-66.6	-48.2	175.7	-35.2	0	0	0	0	111.8	S612 E616 A617 E618	S612-T614 PolarHBondContact O-N 3.27Å; T614-E616 VanDerWaalsContact C-N 3.35Å; T614-E616 PolarHBondContact O-N 2.81Å; T614-A617 WeakPolarHBondContact O-CB 3.36Å; T614-A617 PolarHBondContact O-N 3.49Å; T614-A617 VanDerWaalsContact O-N 3.13Å; T614-E618 PolarHBondContact O-N 3.03Å
615	R	53.2	Low	50.7	Low	158 Å²	158	113.9 Å²	113.9	60%	0.596	55%	0.549	S	S	*	.	H	α-helix	trans	-69.4	-32.3	179	-165.5	178.3	-171.7	-169.5	2.5	112	I611 S612 E618 I619	I611-R615 HydrophobicContact CG2-CB 3.95Å; I611-R615 HydrophobicContact CG2-CG 4.26Å; S612-R615 PolarHBondContact O-N 3.3Å; S612-R615 WeakPolarHBondContact OG-CB 3.42Å; S612-R615 PolarHBondContact OG-N 2.85Å; R615-E618 PolarHBondContact O-N 3.48Å; R615-I619 HydrophobicContact CG-CD1 4.17Å; R615-I619 WeakPolarHBondContact O-CB 3.17Å; R615-I619 WeakPolarHBondContact O-CD1 3.35Å; R615-I619 VanDerWaalsContact O-CG1 3.23Å; R615-I619 WeakPolarHBondContact O-CG1 3.36Å; R615-I619 PolarHBondContact O-N 2.98Å
616	E	57.8	Low	51.7	Low	56 Å²	56	107.6 Å²	107.6	26%	0.262	52%	0.521	S	S	.	.	H	α-helix	trans	-61.7	-43.6	167.9	-71	-171.3	-173.5	0	0	112.1	I611 S612 T614 E618 I619 R620	I611-E616 HydrophobicContact CB-CG 3.98Å; I611-E616 HydrophobicContact CG2-CG 3.71Å; S612-E616 PolarHBondContact O-N 2.99Å; T614-E616 VanDerWaalsContact C-N 3.35Å; T614-E616 PolarHBondContact O-N 2.81Å; E616-E618 VanDerWaalsContact C-N 3.31Å; E616-E618 PolarHBondContact O-N 3.23Å; E616-I619 PolarHBondContact O-N 3.24Å; E616-R620 WeakPolarHBondContact O-CB 3.44Å; E616-R620 WeakPolarHBondContact O-CG 3.34Å; E616-R620 PolarHBondContact O-N 3.46Å; E616-R620 IonicContact OE2-CZ 3.96Å; E616-R620 IonicContact OE2-NH2 3.09Å; E616-R620 PolarHBondContact OE2-NH2 3.16Å
617	A	60	Low	52.6	Low	56 Å²	56	98.3 Å²	98.3	46%	0.463	49%	0.49	S	S	.	.	H	α-helix	trans	-65.6	-35.9	179.8	0	0	0	0	0	112.2	K613 T614 R621	K613-A617 PolarHBondContact O-N 3.47Å; K613-A617 VanDerWaalsContact O-N 3.11Å; T614-A617 WeakPolarHBondContact O-CB 3.36Å; T614-A617 PolarHBondContact O-N 3.49Å; T614-A617 VanDerWaalsContact O-N 3.13Å; A617-R621 PolarHBondContact O-N 3.38Å
618	E	59.8	Low	53.5	Low	88 Å²	88	95.1 Å²	95.1	41%	0.411	47%	0.473	S	S	.	.	H	α-helix	trans	-66	-49.7	173.7	-176.9	170.6	-107.9	0	0	112.3	T614 R615 E616 R620 R621 I622	T614-E618 PolarHBondContact O-N 3.03Å; R615-E618 PolarHBondContact O-N 3.48Å; E616-E618 VanDerWaalsContact C-N 3.31Å; E616-E618 PolarHBondContact O-N 3.23Å; E618-R620 VanDerWaalsContact C-N 3.32Å; E618-R620 PolarHBondContact O-N 3.23Å; E618-R621 WeakPolarHBondContact O-CA 3.36Å; E618-R621 VanDerWaalsContact O-CB 3.3Å; E618-R621 WeakPolarHBondContact O-CB 3.3Å; E618-R621 PolarHBondContact O-N 3.13Å; E618-I622 HydrophobicContact CG-CD1 4.18Å; E618-I622 WeakPolarHBondContact O-CG1 3.28Å; E618-I622 PolarHBondContact O-N 3.48Å
619	I	62.1	Low	53.8	Low	70 Å²	70	91.5 Å²	91.5	36%	0.359	46%	0.455	S	S	.	.	H	α-helix	trans	-58.9	-43.1	174.3	-68.9	164.5	0	0	0	110.9	R615 E616 R621 I622 L623	R615-I619 HydrophobicContact CG-CD1 4.17Å; R615-I619 WeakPolarHBondContact O-CB 3.17Å; R615-I619 WeakPolarHBondContact O-CD1 3.35Å; R615-I619 VanDerWaalsContact O-CG1 3.23Å; R615-I619 WeakPolarHBondContact O-CG1 3.36Å; R615-I619 PolarHBondContact O-N 2.98Å; E616-I619 PolarHBondContact O-N 3.24Å; I619-R621 VanDerWaalsContact C-N 3.29Å; I619-R621 PolarHBondContact O-N 3.49Å; I619-I622 PolarHBondContact O-N 3Å; I619-L623 HydrophobicContact CG2-CD1 3.8Å; I619-L623 HydrophobicContact CG2-CG 4.46Å; I619-L623 WeakPolarHBondContact O-CB 3.29Å; I619-L623 WeakPolarHBondContact O-CG 3.19Å; I619-L623 PolarHBondContact O-N 3.37Å
620	R	53.9	Low	53.4	Low	48 Å²	48	90.3 Å²	90.3	18%	0.181	45%	0.446	C	S	.	.	H	α-helix	trans	-59.8	-36.9	173.1	-71.3	170.7	-148.5	-124.8	8	112.1	E509 E616 E618 R624	E509-R620 IonicContact OE2-NH1 3.83Å; E616-R620 WeakPolarHBondContact O-CB 3.44Å; E616-R620 WeakPolarHBondContact O-CG 3.34Å; E616-R620 PolarHBondContact O-N 3.46Å; E616-R620 IonicContact OE2-CZ 3.96Å; E616-R620 IonicContact OE2-NH2 3.09Å; E616-R620 PolarHBondContact OE2-NH2 3.16Å; E618-R620 VanDerWaalsContact C-N 3.32Å; E618-R620 PolarHBondContact O-N 3.23Å; R620-R624 WeakPolarHBondContact O-CB 3.25Å; R620-R624 VanDerWaalsContact O-CG 3.26Å; R620-R624 WeakPolarHBondContact O-CG 3.08Å; R620-R624 PolarHBondContact O-N 3.5Å
621	R	59.2	Low	53.3	Low	125 Å²	125	84.7 Å²	84.7	47%	0.472	42%	0.419	S	S	.	.	H	α-helix	trans	-67.1	-47.6	177.2	-168.2	-173.4	-161.8	162.3	9.4	111.3	A617 E618 I619 A625	A617-R621 PolarHBondContact O-N 3.38Å; E618-R621 WeakPolarHBondContact O-CA 3.36Å; E618-R621 VanDerWaalsContact O-CB 3.3Å; E618-R621 WeakPolarHBondContact O-CB 3.3Å; E618-R621 PolarHBondContact O-N 3.13Å; I619-R621 VanDerWaalsContact C-N 3.29Å; I619-R621 PolarHBondContact O-N 3.49Å; R621-A625 WeakPolarHBondContact O-CB 3.12Å; R621-A625 PolarHBondContact O-N 3.43Å
622	I	59.4	Low	52.7	Low	60 Å²	60	87.5 Å²	87.5	31%	0.308	43%	0.43	S	S	.	.	H	α-helix	trans	-64.5	-45.8	-178.5	-65.7	165.5	0	0	0	110.7	E618 I619 A625 N626	E618-I622 HydrophobicContact CG-CD1 4.18Å; E618-I622 WeakPolarHBondContact O-CG1 3.28Å; E618-I622 PolarHBondContact O-N 3.48Å; I619-I622 PolarHBondContact O-N 3Å; I622-A625 PolarHBondContact O-N 3.25Å; I622-N626 WeakPolarHBondContact O-CB 3.22Å; I622-N626 PolarHBondContact O-N 2.95Å; I622-N626 PolarHBondContact O-ND2 3.43Å
623	L	55.1	Low	51.8	Low	69 Å²	69	95.1 Å²	95.1	36%	0.361	45%	0.449	S	S	.	.	H	α-helix	trans	-61.7	-48.9	178.1	-77.9	167.3	0	0	0	112.4	I510 I619 A625 N626 L627	I510-L623 HydrophobicContact CD1-CD1 4.11Å; I619-L623 HydrophobicContact CG2-CD1 3.8Å; I619-L623 HydrophobicContact CG2-CG 4.46Å; I619-L623 WeakPolarHBondContact O-CB 3.29Å; I619-L623 WeakPolarHBondContact O-CG 3.19Å; I619-L623 PolarHBondContact O-N 3.37Å; L623-A625 VanDerWaalsContact C-N 3.35Å; L623-A625 PolarHBondContact O-N 2.86Å; L623-N626 PolarHBondContact O-N 3.17Å; L623-L627 PolarHBondContact O-N 2.87Å
624	R	53	Low	50.8	Low	93 Å²	93	92 Å²	92	35%	0.351	44%	0.44	S	S	.	.	H	α-helix	trans	-62.2	-41.1	178.4	-70.5	-177	-163.4	130.8	-8.6	112.1	E509 R620 Q628	E509-R624 IonicContact OE1-CZ 2.74Å; E509-R624 IonicContact OE1-NE 3.93Å; E509-R624 PolarHBondContact OE1-NE 3.06Å; E509-R624 IonicContact OE1-NH2 2.66Å; E509-R624 PolarHBondContact OE1-NH2 2.79Å; E509-R624 IonicContact OE2-NH2 3.18Å; R620-R624 WeakPolarHBondContact O-CB 3.25Å; R620-R624 VanDerWaalsContact O-CG 3.26Å; R620-R624 WeakPolarHBondContact O-CG 3.08Å; R620-R624 PolarHBondContact O-N 3.5Å; R624-Q628 WeakPolarHBondContact O-CB 3.47Å; R624-Q628 VanDerWaalsContact O-CG 3.29Å; R624-Q628 WeakPolarHBondContact O-CG 3.36Å; R624-Q628 PolarHBondContact O-N 3.34Å; R624-Q628 VanDerWaalsContact O-N 3.11Å
625	A	51.5	Low	50	Low	30 Å²	30	97 Å²	97	25%	0.248	45%	0.446	C	S	.	.	H	α-helix	trans	-62.4	-42.7	176.7	0	0	0	0	0	111.8	R621 I622 L623 N629	R621-A625 WeakPolarHBondContact O-CB 3.12Å; R621-A625 PolarHBondContact O-N 3.43Å; I622-A625 PolarHBondContact O-N 3.25Å; L623-A625 VanDerWaalsContact C-N 3.35Å; L623-A625 PolarHBondContact O-N 2.86Å; A625-N629 WeakPolarHBondContact O-CB 3.5Å; A625-N629 PolarHBondContact O-N 2.85Å; A625-N629 PolarHBondContact O-ND2 3.46Å; A625-N629 VanDerWaalsContact O-ND2 3.08Å
626	N	50.3	Low	49.1	Very low	52 Å²	52	94.7 Å²	94.7	28%	0.278	45%	0.454	S	S	.	.	H	α-helix	trans	-70.2	-45.6	179.3	-79.4	-33.2	0	0	0	113.1	M570 I622 L623 Q628 N629 T630	M570-N626 VanDerWaalsContact CE-OD1 3.3Å; M570-N626 WeakPolarHBondContact CE-OD1 3.44Å; M570-N626 PolarHBondContact SD-ND2 2.61Å; M570-N626 PolarHBondContact SD-OD1 3.08Å; I622-N626 WeakPolarHBondContact O-CB 3.22Å; I622-N626 PolarHBondContact O-N 2.95Å; I622-N626 PolarHBondContact O-ND2 3.43Å; L623-N626 PolarHBondContact O-N 3.17Å; N626-Q628 VanDerWaalsContact C-N 3.29Å; N626-Q628 PolarHBondContact O-N 3.04Å; N626-N629 PolarHBondContact O-N 3.25Å; N626-T630 PolarHBondContact O-N 2.91Å; N626-T630 PolarHBondContact O-OG1 3.18Å
627	L	50.6	Low	48.2	Very low	51 Å²	51	102 Å²	102	27%	0.267	48%	0.48	S	S	.	.	H	α-helix	trans	-56.7	-42.2	175.2	-91.5	155.6	0	0	0	112.2	L623	L623-L627 PolarHBondContact O-N 2.87Å
628	Q	50.6	Low	46.8	Very low	115 Å²	115	102.2 Å²	102.2	54%	0.537	48%	0.479	S	S	.	.	H	α-helix	trans	-68.2	-38.6	176.8	-71.7	179.5	-6.4	0	0	113	R624 N626 R631	R624-Q628 WeakPolarHBondContact O-CB 3.47Å; R624-Q628 VanDerWaalsContact O-CG 3.29Å; R624-Q628 WeakPolarHBondContact O-CG 3.36Å; R624-Q628 PolarHBondContact O-N 3.34Å; R624-Q628 VanDerWaalsContact O-N 3.11Å; N626-Q628 VanDerWaalsContact C-N 3.29Å; N626-Q628 PolarHBondContact O-N 3.04Å; Q628-R631 PolarHBondContact O-N 2.83Å
629	N	44.5	Very low	45.7	Very low	77 Å²	77	108.9 Å²	108.9	41%	0.412	50%	0.5	S	S	.	.	H	α-helix	trans	-68	-33	178.4	-75	-27.1	0	0	0	112.9	A625 N626 R631 Q632 R633	A625-N629 WeakPolarHBondContact O-CB 3.5Å; A625-N629 PolarHBondContact O-N 2.85Å; A625-N629 PolarHBondContact O-ND2 3.46Å; A625-N629 VanDerWaalsContact O-ND2 3.08Å; N626-N629 PolarHBondContact O-N 3.25Å; N629-R631 VanDerWaalsContact C-N 3.28Å; N629-R631 PolarHBondContact O-N 3.06Å; N629-Q632 PolarHBondContact O-N 2.88Å; N629-Q632 VanDerWaalsContact O-N 3.14Å; N629-R633 PolarHBondContact O-N 2.99Å
630	T	35.8	Very low	44.5	Very low	85 Å²	85	113.5 Å²	113.5	52%	0.521	52%	0.52	S	S	.	.	H	α-helix	trans	-60.1	-38.6	176.2	-52.2	0	0	0	0	111.6	N626 Q632 R633	N626-T630 PolarHBondContact O-N 2.91Å; N626-T630 PolarHBondContact O-OG1 3.18Å; T630-Q632 VanDerWaalsContact C-N 3.32Å; T630-Q632 PolarHBondContact O-N 3.45Å; T630-R633 PolarHBondContact O-N 2.91Å
631	R	40.6	Very low	43.8	Very low	91 Å²	91	115.7 Å²	115.7	34%	0.343	54%	0.535	S	S	.	.	H	α-helix	trans	-70.3	-24.1	177.1	-166	173.7	177.6	-148.8	-4.1	113.4	T520 D524 D536 Q628 N629	T520-R631 VanDerWaalsContact CG2-NH2 3.27Å; D524-R631 IonicContact OD2-NH2 3.43Å; D536-R631 IonicContact OD1-NH1 2.98Å; D536-R631 IonicContact OD2-CZ 2.82Å; D536-R631 IonicContact OD2-NH1 3.74Å; D536-R631 PolarHBondContact OD2-NH1 3.41Å; D536-R631 IonicContact OD2-NH2 3.72Å; D536-R631 PolarHBondContact OD2-NH2 3Å; Q628-R631 PolarHBondContact O-N 2.83Å; N629-R631 VanDerWaalsContact C-N 3.28Å; N629-R631 PolarHBondContact O-N 3.06Å
632	Q	43	Very low	42.6	Very low	150 Å²	150	118.6 Å²	118.6	70%	0.701	55%	0.552	S	S	*	*	H	α-helix	trans	-77.5	-19	173.9	-73.7	-171	-24	0	0	113.8	N629 T630	N629-Q632 PolarHBondContact O-N 2.88Å; N629-Q632 VanDerWaalsContact O-N 3.14Å; T630-Q632 VanDerWaalsContact C-N 3.32Å; T630-Q632 PolarHBondContact O-N 3.45Å
633	R	40.2	Very low	41.5	Very low	225 Å²	225	125.3 Å²	125.3	85%	0.849	58%	0.579	S	S	*	*	H	α-helix	trans	-80.9	-21.8	177.4	-71.4	-177.3	174.6	178.8	-1.8	113.5	N629 T630	N629-R633 PolarHBondContact O-N 2.99Å; T630-R633 PolarHBondContact O-N 2.91Å
634	L	35.1	Very low	40.6	Very low	118 Å²	118	127 Å²	127	62%	0.618	59%	0.586	S	S	*	*	S	Bend	trans	-100.1	108.8	177.7	-70.7	162.3	0	0	0	109
635	R	34.9	Very low	39.7	Very low	221 Å²	221	128.4 Å²	128.4	83%	0.834	60%	0.601	S	S	*	*			trans	-61.1	145.7	165.6	-86.7	-170.1	172	-166.8	1	109	Y637	R635-Y637 WeakPolarHBondContact O-CD2 3.41Å; R635-Y637 PolarHBondContact O-N 2.92Å; R635-Y637 VanDerWaalsContact O-N 3.14Å
636	S	33	Very low	39.4	Very low	108 Å²	108	132 Å²	132	76%	0.755	62%	0.622	S	S	*	*			trans	-65.1	109	167.2	51	0	0	0	0	109.2	S638	S636-S638 PolarHBondContact O-N 2.89Å
637	Y	38.7	Very low	38.8	Very low	209 Å²	209	137.4 Å²	137.4	82%	0.82	64%	0.643	S	S	*	*			trans	-68.7	116.4	176.7	-76.5	-86.3	0	0	0	110.4	R635	R635-Y637 WeakPolarHBondContact O-CD2 3.41Å; R635-Y637 PolarHBondContact O-N 2.92Å; R635-Y637 VanDerWaalsContact O-N 3.14Å
638	S	31.7	Very low	38.6	Very low	61 Å²	61	140.7 Å²	140.7	43%	0.427	66%	0.657	S	S	.	*			trans	-85.8	140	168.5	-179.3	0	0	0	0	109.5	S636 H640 D641	S636-S638 PolarHBondContact O-N 2.89Å; S638-H640 PolarHBondContact O-N 2.9Å; S638-D641 PolarHBondContact O-N 3.13Å; S638-D641 VanDerWaalsContact O-N 3.12Å
639	R	36.1	Very low	38.2	Very low	229 Å²	229	140 Å²	140	86%	0.864	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.5	-12.5	178.7	-171.5	172.3	176.3	174.9	-1.2	114
640	H	38.3	Very low	38.1	Very low	166 Å²	166	141.5 Å²	141.5	77%	0.769	67%	0.665	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.1	-11.8	-179.5	-65.6	83.1	0	0	0	114.3	S638 F642	S638-H640 PolarHBondContact O-N 2.9Å; H640-F642 PolarHBondContact O-N 3.11Å
641	D	37.9	Very low	38.2	Very low	94 Å²	94	142.4 Å²	142.4	50%	0.503	66%	0.664	S	S	.	*	T	Hydrogen-bonded Turn	trans	-82.7	9.7	179	-63.7	-25.2	0	0	0	113	S638 F643	S638-D641 PolarHBondContact O-N 3.13Å; S638-D641 VanDerWaalsContact O-N 3.12Å; D641-F643 PolarHBondContact O-N 3.24Å
642	F	33.8	Very low	38.4	Very low	187 Å²	187	140 Å²	140	82%	0.82	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.2	-9.4	-172.9	-130.8	-85.7	0	0	0	114.4	H640	H640-F642 PolarHBondContact O-N 3.11Å
643	F	37.3	Very low	38.6	Very low	200 Å²	200	137.2 Å²	137.2	88%	0.877	65%	0.649	S	S	*	*	S	Bend	trans	-113.4	84	169.8	-69.9	-80.1	0	0	0	109	D641	D641-F643 PolarHBondContact O-N 3.24Å
644	M	35.3	Very low	39.2	Very low	106 Å²	106	130.4 Å²	130.4	52%	0.522	63%	0.632	S	S	.	*			trans	-76.5	130.2	172.4	-74.2	-99.6	63.2	0	0	110.4
645	D	35	Very low	39.9	Very low	121 Å²	121	131.9 Å²	131.9	65%	0.647	63%	0.629	S	S	*	*			trans	-77	126.9	172.7	-131.5	-26.2	0	0	0	109.3	F647 E648	D645-F647 PolarHBondContact O-N 3.37Å; D645-E648 PolarHBondContact O-N 3.11Å
646	P	44.7	Very low	40.6	Very low	106 Å²	106	128 Å²	128	69%	0.688	62%	0.619	S	S	*	*	H	α-helix	trans	-59.1	-8.3	-174.4	-26.8	35	0	0	0	116.1
647	F	38.1	Very low	41.6	Very low	165 Å²	165	130.5 Å²	130.5	72%	0.724	61%	0.612	S	S	*	*	H	α-helix	trans	-84.9	-29.5	-178.8	-127.1	-92.3	0	0	0	113.8	D645 M651	D645-F647 PolarHBondContact O-N 3.37Å; F647-M651 PolarHBondContact O-N 3.18Å
648	E	45.5	Very low	42.2	Very low	120 Å²	120	129.9 Å²	129.9	56%	0.561	61%	0.608	S	S	*	*	H	α-helix	trans	-73.4	-37.6	-177.4	-79.2	-136.4	113.4	0	0	112.8	D645 N650 M651 S652	D645-E648 PolarHBondContact O-N 3.11Å; E648-N650 PolarHBondContact O-N 3.21Å; E648-M651 PolarHBondContact O-N 2.78Å; E648-S652 WeakPolarHBondContact O-CB 3.5Å; E648-S652 PolarHBondContact O-N 2.82Å
649	D	43.2	Very low	43.2	Very low	102 Å²	102	133.1 Å²	133.1	55%	0.545	62%	0.616	S	S	.	*	H	α-helix	trans	-59.1	-49	178	-91.2	-21.8	0	0	0	111.2	M651 S652 E653	D649-M651 VanDerWaalsContact C-N 3.34Å; D649-M651 PolarHBondContact O-N 3.04Å; D649-S652 PolarHBondContact O-N 3.15Å; D649-S652 VanDerWaalsContact O-N 3.14Å; D649-S652 PolarHBondContact O-OG 2.97Å; D649-E653 PolarHBondContact O-N 2.91Å
650	N	41.4	Very low	44	Very low	107 Å²	107	130.3 Å²	130.3	57%	0.572	61%	0.606	S	S	*	*	H	α-helix	trans	-57.9	-44.3	174.9	-107.1	-39.4	0	0	0	112.1	E648 S652 E653 V654	E648-N650 PolarHBondContact O-N 3.21Å; N650-S652 VanDerWaalsContact C-N 3.28Å; N650-S652 PolarHBondContact O-N 3.29Å; N650-E653 PolarHBondContact O-N 3.14Å; N650-V654 WeakPolarHBondContact O-CB 3.31Å; N650-V654 WeakPolarHBondContact O-CG2 3.49Å; N650-V654 PolarHBondContact O-N 3.12Å
651	M	38.6	Very low	45.2	Very low	104 Å²	104	126 Å²	126	51%	0.512	59%	0.591	S	S	.	*	H	α-helix	trans	-66.2	-29.5	178.9	-165.6	77	75	0	0	112.8	F647 E648 D649 R655	F647-M651 PolarHBondContact O-N 3.18Å; E648-M651 PolarHBondContact O-N 2.78Å; D649-M651 VanDerWaalsContact C-N 3.34Å; D649-M651 PolarHBondContact O-N 3.04Å; M651-R655 PolarHBondContact O-N 3.21Å; M651-R655 PolarHBondContact O-NE 3.46Å
652	S	44.4	Very low	46	Very low	41 Å²	41	126.5 Å²	126.5	29%	0.287	59%	0.59	S	S	.	*	H	α-helix	trans	-78.9	-44.2	176.2	85.2	0	0	0	0	111.4	E648 D649 N650 R655 F656	E648-S652 WeakPolarHBondContact O-CB 3.5Å; E648-S652 PolarHBondContact O-N 2.82Å; D649-S652 PolarHBondContact O-N 3.15Å; D649-S652 VanDerWaalsContact O-N 3.14Å; D649-S652 PolarHBondContact O-OG 2.97Å; N650-S652 VanDerWaalsContact C-N 3.28Å; N650-S652 PolarHBondContact O-N 3.29Å; S652-R655 WeakPolarHBondContact O-CB 3.48Å; S652-R655 PolarHBondContact O-N 3.07Å; S652-R655 VanDerWaalsContact O-N 3.15Å; S652-F656 VanDerWaalsContact O-CD2 3.28Å; S652-F656 WeakPolarHBondContact O-CD2 3.44Å; S652-F656 PolarHBondContact O-N 3.37Å
653	E	48.4	Very low	46.6	Very low	92 Å²	92	123.1 Å²	123.1	43%	0.43	58%	0.578	S	S	.	*	H	α-helix	trans	-66.5	-41.4	179.8	-153.9	-159.2	139.8	0	0	111.3	D649 N650 R655 F656 R657	D649-E653 PolarHBondContact O-N 2.91Å; N650-E653 PolarHBondContact O-N 3.14Å; E653-R655 VanDerWaalsContact C-N 3.29Å; E653-R655 PolarHBondContact O-N 3.24Å; E653-F656 PolarHBondContact O-N 2.76Å; E653-R657 WeakPolarHBondContact O-CG 3.45Å; E653-R657 PolarHBondContact O-N 2.8Å; E653-R657 IonicContact OE1-CZ 3.19Å; E653-R657 IonicContact OE1-NE 2.69Å; E653-R657 PolarHBondContact OE1-NE 3.43Å; E653-R657 IonicContact OE1-NH2 2.94Å; E653-R657 PolarHBondContact OE1-NH2 3.25Å
654	V	52.8	Low	47.2	Very low	82 Å²	82	117.6 Å²	117.6	50%	0.497	56%	0.555	S	S	.	*	H	α-helix	trans	-60.9	-37.1	173.1	169.8	0	0	0	0	111.5	N650 R658	N650-V654 WeakPolarHBondContact O-CB 3.31Å; N650-V654 WeakPolarHBondContact O-CG2 3.49Å; N650-V654 PolarHBondContact O-N 3.12Å; V654-R658 WeakPolarHBondContact O-CB 3.28Å; V654-R658 PolarHBondContact O-N 3.06Å
655	R	48.3	Very low	47.9	Very low	148 Å²	148	121.4 Å²	121.4	56%	0.558	56%	0.564	S	S	*	*	H	α-helix	trans	-65.6	-44.5	173.3	-97.6	-177.6	-72.3	-172.3	-1.5	112.2	M651 S652 E653 R658 Q659	M651-R655 PolarHBondContact O-N 3.21Å; M651-R655 PolarHBondContact O-NE 3.46Å; S652-R655 WeakPolarHBondContact O-CB 3.48Å; S652-R655 PolarHBondContact O-N 3.07Å; S652-R655 VanDerWaalsContact O-N 3.15Å; E653-R655 VanDerWaalsContact C-N 3.29Å; E653-R655 PolarHBondContact O-N 3.24Å; R655-R658 PolarHBondContact O-N 3.12Å; R655-Q659 PolarHBondContact O-N 3.18Å
656	F	50	Low	48.4	Very low	141 Å²	141	123.6 Å²	123.6	62%	0.618	56%	0.563	S	S	*	*	H	α-helix	trans	-64.8	-40.6	176.1	-80.9	-65.7	0	0	0	112.3	S652 E653 Q659 R660	S652-F656 VanDerWaalsContact O-CD2 3.28Å; S652-F656 WeakPolarHBondContact O-CD2 3.44Å; S652-F656 PolarHBondContact O-N 3.37Å; E653-F656 PolarHBondContact O-N 2.76Å; F656-Q659 PolarHBondContact O-N 3.37Å; F656-R660 WeakPolarHBondContact O-CB 3.36Å; F656-R660 PolarHBondContact O-N 3.44Å
657	R	53.4	Low	48.1	Very low	160 Å²	160	123 Å²	123	60%	0.604	55%	0.552	S	S	*	*	H	α-helix	trans	-61.4	-43.8	172.5	-71	-177.2	-174	-153.2	7.6	111.5	E653 R660 V661	E653-R657 WeakPolarHBondContact O-CG 3.45Å; E653-R657 PolarHBondContact O-N 2.8Å; E653-R657 IonicContact OE1-CZ 3.19Å; E653-R657 IonicContact OE1-NE 2.69Å; E653-R657 PolarHBondContact OE1-NE 3.43Å; E653-R657 IonicContact OE1-NH2 2.94Å; E653-R657 PolarHBondContact OE1-NH2 3.25Å; R657-R660 PolarHBondContact O-N 3Å; R657-V661 WeakPolarHBondContact O-CG2 3.49Å; R657-V661 PolarHBondContact O-N 2.9Å
658	R	53.2	Low	48.3	Very low	195 Å²	195	118.9 Å²	118.9	74%	0.736	54%	0.544	S	S	*	.	H	α-helix	trans	-59.8	-50.3	174.2	-103.6	-175.1	174.6	179.1	-0.4	112.4	V654 R655 R660 V661 E662	V654-R658 WeakPolarHBondContact O-CB 3.28Å; V654-R658 PolarHBondContact O-N 3.06Å; R655-R658 PolarHBondContact O-N 3.12Å; R658-R660 VanDerWaalsContact C-N 3.27Å; R658-R660 PolarHBondContact O-N 3.31Å; R658-V661 PolarHBondContact O-N 3.3Å; R658-E662 WeakPolarHBondContact O-CB 3.36Å; R658-E662 PolarHBondContact O-N 3.14Å
659	Q	52.1	Low	48.2	Very low	129 Å²	129	120.7 Å²	120.7	60%	0.603	55%	0.552	S	S	*	*	H	α-helix	trans	-60.8	-36.9	177.5	-79.2	-172.4	-24.9	0	0	112.4	R655 F656 E662 M663	R655-Q659 PolarHBondContact O-N 3.18Å; F656-Q659 PolarHBondContact O-N 3.37Å; Q659-E662 PolarHBondContact O-N 3.29Å; Q659-M663 WeakPolarHBondContact O-CB 3.39Å; Q659-M663 PolarHBondContact O-N 2.86Å
660	R	51.5	Low	48.1	Very low	171 Å²	171	125.7 Å²	125.7	65%	0.645	57%	0.565	S	S	*	*	H	α-helix	trans	-65.4	-48.3	175.7	-176.7	176.2	175.3	169.2	1.6	111.9	F656 R657 R658 E662 M663 E664	F656-R660 WeakPolarHBondContact O-CB 3.36Å; F656-R660 PolarHBondContact O-N 3.44Å; R657-R660 PolarHBondContact O-N 3Å; R658-R660 VanDerWaalsContact C-N 3.27Å; R658-R660 PolarHBondContact O-N 3.31Å; R660-E662 PolarHBondContact O-N 3.12Å; R660-E662 VanDerWaalsContact C-N 3.29Å; R660-M663 PolarHBondContact O-N 3.17Å; R660-E664 WeakPolarHBondContact CG-OE1 3.42Å; R660-E664 IonicContact CZ-OE1 3.47Å; R660-E664 IonicContact NE-OE1 3.21Å; R660-E664 PolarHBondContact NE-OE1 3.41Å; R660-E664 IonicContact NH2-OE1 2.77Å; R660-E664 WeakPolarHBondContact O-CB 3.33Å; R660-E664 WeakPolarHBondContact O-CG 3.39Å; R660-E664 PolarHBondContact O-N 3.29Å
661	V	64.6	Low	48	Very low	75 Å²	75	127.4 Å²	127.4	46%	0.455	57%	0.573	S	S	.	*	H	α-helix	trans	-62.4	-36.9	176.5	170.5	0	0	0	0	111.7	R657 R658 R665	R657-V661 WeakPolarHBondContact O-CG2 3.49Å; R657-V661 PolarHBondContact O-N 2.9Å; R658-V661 PolarHBondContact O-N 3.3Å; V661-R665 WeakPolarHBondContact O-CG 3.48Å; V661-R665 PolarHBondContact O-N 3.01Å; V661-R665 WeakPolarHBondContact O-CB 3.34Å
662	E	54.3	Low	48.1	Very low	104 Å²	104	127.4 Å²	127.4	49%	0.486	58%	0.579	S	S	.	*	H	α-helix	trans	-71.8	-36.5	177.4	-167.5	169.5	-161.9	0	0	112.2	R658 Q659 R660 R666	R658-E662 WeakPolarHBondContact O-CB 3.36Å; R658-E662 PolarHBondContact O-N 3.14Å; Q659-E662 PolarHBondContact O-N 3.29Å; R660-E662 PolarHBondContact O-N 3.12Å; R660-E662 VanDerWaalsContact C-N 3.29Å; E662-R666 WeakPolarHBondContact O-CG 3.04Å; E662-R666 PolarHBondContact O-N 3.47Å; E662-R666 IonicContact OE1-NH2 3.8Å
663	M	47.3	Very low	47.6	Very low	116 Å²	116	131.6 Å²	131.6	57%	0.571	60%	0.603	S	S	*	*	H	α-helix	trans	-70.2	-37.7	172.1	-178.5	170.5	172.1	0	0	112.3	Q659 R660 R666 M667	Q659-M663 WeakPolarHBondContact O-CB 3.39Å; Q659-M663 PolarHBondContact O-N 2.86Å; R660-M663 PolarHBondContact O-N 3.17Å; M663-R666 PolarHBondContact O-N 3.07Å; M663-M667 HydrophobicContact CE-CE 3.72Å; M663-M667 HydrophobicContact CG-CE 3.82Å; M663-M667 PolarHBondContact O-N 2.89Å
664	E	48.9	Very low	46.9	Very low	84 Å²	84	132.9 Å²	132.9	39%	0.393	62%	0.619	S	S	.	*	H	α-helix	trans	-65.1	-46.1	172.9	-77.1	167.9	-173.8	0	0	110.5	R660 R666 M667 S668	R660-E664 WeakPolarHBondContact CG-OE1 3.42Å; R660-E664 IonicContact CZ-OE1 3.47Å; R660-E664 IonicContact NE-OE1 3.21Å; R660-E664 PolarHBondContact NE-OE1 3.41Å; R660-E664 IonicContact NH2-OE1 2.77Å; R660-E664 WeakPolarHBondContact O-CB 3.33Å; R660-E664 WeakPolarHBondContact O-CG 3.39Å; R660-E664 PolarHBondContact O-N 3.29Å; E664-R666 VanDerWaalsContact C-N 3.32Å; E664-R666 PolarHBondContact O-N 3.42Å; E664-M667 PolarHBondContact O-N 3.35Å; E664-M667 VanDerWaalsContact O-N 3.08Å; E664-S668 PolarHBondContact O-N 3.33Å; E664-S668 PolarHBondContact O-OG 3.24Å; E664-S668 VanDerWaalsContact O-OG 3.11Å
665	R	50	Low	45.9	Very low	186 Å²	186	133.5 Å²	133.5	70%	0.702	63%	0.632	S	S	*	*	H	α-helix	trans	-56.1	-42.5	171.6	-83.7	-177.7	173.1	168.7	-1.6	112.9	V661 S668 H669	V661-R665 WeakPolarHBondContact O-CG 3.48Å; V661-R665 PolarHBondContact O-N 3.01Å; V661-R665 WeakPolarHBondContact O-CB 3.34Å; R665-S668 PolarHBondContact O-N 3.13Å; R665-H669 PolarHBondContact O-N 2.9Å
666	R	46.7	Very low	44.9	Very low	167 Å²	167	136.3 Å²	136.3	63%	0.63	65%	0.649	S	S	*	*	H	α-helix	trans	-65.4	-40.3	175.1	-73	178	-171.3	-159.9	4.6	111.6	E662 M663 E664 H669 Y670	E662-R666 WeakPolarHBondContact O-CG 3.04Å; E662-R666 PolarHBondContact O-N 3.47Å; E662-R666 IonicContact OE1-NH2 3.8Å; M663-R666 PolarHBondContact O-N 3.07Å; E664-R666 VanDerWaalsContact C-N 3.32Å; E664-R666 PolarHBondContact O-N 3.42Å; R666-H669 PolarHBondContact O-N 3.46Å; R666-Y670 WeakPolarHBondContact O-CD2 3.33Å
667	M	38.1	Very low	43.8	Very low	94 Å²	94	138.3 Å²	138.3	46%	0.463	66%	0.66	S	S	.	*	H	α-helix	trans	-64.3	-40.8	175.1	-110.4	177.2	-68.3	0	0	112.7	M663 E664 H669 Y670 L671	M663-M667 HydrophobicContact CE-CE 3.72Å; M663-M667 HydrophobicContact CG-CE 3.82Å; M663-M667 PolarHBondContact O-N 2.89Å; E664-M667 PolarHBondContact O-N 3.35Å; E664-M667 VanDerWaalsContact O-N 3.08Å; M667-H669 VanDerWaalsContact C-N 3.27Å; M667-H669 PolarHBondContact O-N 3.24Å; M667-Y670 PolarHBondContact O-N 3.43Å; M667-L671 PolarHBondContact O-N 3.22Å
668	S	42.3	Very low	42.5	Very low	79 Å²	79	139.4 Å²	139.4	55%	0.552	67%	0.672	S	S	*	*	H	α-helix	trans	-59.7	-37.2	175.9	-58.3	0	0	0	0	112.4	E664 R665 Y670 L671	E664-S668 PolarHBondContact O-N 3.33Å; E664-S668 PolarHBondContact O-OG 3.24Å; E664-S668 VanDerWaalsContact O-OG 3.11Å; R665-S668 PolarHBondContact O-N 3.13Å; S668-Y670 PolarHBondContact O-N 3.24Å; S668-L671 PolarHBondContact O-N 3.19Å
669	H	42.1	Very low	41.2	Very low	158 Å²	158	139.1 Å²	139.1	73%	0.731	68%	0.679	S	S	*	*	H	α-helix	trans	-67.4	-18.4	175.4	-95.7	-49.7	0	0	0	114.8	R665 R666 M667	R665-H669 PolarHBondContact O-N 2.9Å; R666-H669 PolarHBondContact O-N 3.46Å; M667-H669 VanDerWaalsContact C-N 3.27Å; M667-H669 PolarHBondContact O-N 3.24Å
670	Y	40.6	Very low	40.2	Very low	207 Å²	207	139 Å²	139	81%	0.812	69%	0.687	S	S	*	*	T	Hydrogen-bonded Turn	trans	-98.8	-3	176.7	-74.1	-71.1	0	0	0	113.9	R666 M667 S668	R666-Y670 WeakPolarHBondContact O-CD2 3.33Å; M667-Y670 PolarHBondContact O-N 3.43Å; S668-Y670 PolarHBondContact O-N 3.24Å
671	L	40.5	Very low	39	Very low	142 Å²	142	136.7 Å²	136.7	74%	0.743	69%	0.694	S	S	*	*	T	Hydrogen-bonded Turn	trans	-107.8	-7.4	-176.9	-86	164.7	0	0	0	114.9	M667 S668 V673	M667-L671 PolarHBondContact O-N 3.22Å; S668-L671 PolarHBondContact O-N 3.19Å; L671-V673 PolarHBondContact O-N 3Å
672	T	40.4	Very low	37.2	Very low	105 Å²	105	139 Å²	139	64%	0.644	71%	0.714	S	S	*	*			trans	-88.5	87.8	172.3	53.8	0	0	0	0	111.2
673	V	34.5	Very low	36	Very low	129 Å²	129	140.7 Å²	140.7	78%	0.782	73%	0.731	S	S	*	*	P	Polyproline II helix	trans	-64	128.8	157.7	179.4	0	0	0	0	107.5	L671 A675	L671-V673 PolarHBondContact O-N 3Å; V673-A675 PolarHBondContact O-N 3.04Å
674	P	34.1	Very low	35	Very low	118 Å²	118	146.4 Å²	146.4	77%	0.766	75%	0.746	S	S	*	*	P	Polyproline II helix	trans	-65.5	119.2	176	-16.9	30	0	0	0	109.7
675	A	30.4	Very low	34.1	Very low	95 Å²	95	151.9 Å²	151.9	79%	0.785	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-63.6	139.6	167.4	0	0	0	0	0	109.2	V673 Q677	V673-A675 PolarHBondContact O-N 3.04Å; A675-Q677 PolarHBondContact O-N 2.98Å
676	K	26.9	Very low	33.1	Very low	207 Å²	207	149.4 Å²	149.4	90%	0.9	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-59.4	119.9	-178	-161.3	177.8	-175.5	-176.1	0	109.4	Q678	K676-Q678 PolarHBondContact O-N 2.75Å
677	Q	27.2	Very low	32	Very low	184 Å²	184	152.6 Å²	152.6	86%	0.86	79%	0.786	S	S	*	*	P	Polyproline II helix	trans	-65.4	121.4	-175.3	-166.7	168.6	0.6	0	0	110	A675	A675-Q677 PolarHBondContact O-N 2.98Å
678	Q	27.3	Very low	31.4	Very low	182 Å²	182	157.8 Å²	157.8	85%	0.85	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-96.8	116.4	176.9	-168.1	167	-3.2	0	0	107.7	K676	K676-Q678 PolarHBondContact O-N 2.75Å
679	E	26.1	Very low	30.6	Very low	189 Å²	189	162.7 Å²	162.7	88%	0.883	82%	0.821	S	S	*	*	P	Polyproline II helix	trans	-68	132.7	-175	-64.5	-175.4	157.5	0	0	111.6
680	T	29.5	Very low	30.2	Very low	126 Å²	126	160.9 Å²	160.9	77%	0.773	82%	0.823	S	S	*	*			trans	-121.4	144.9	162.7	51.5	0	0	0	0	108.9
681	P	28.1	Very low	29.6	Very low	123 Å²	123	160.5 Å²	160.5	80%	0.799	83%	0.829	S	S	*	*	P	Polyproline II helix	trans	-74.7	156.6	-163.9	28.9	-35.6	0	0	0	113.8	V683	P681-V683 PolarHBondContact O-N 3.18Å
682	S	26.6	Very low	29	Very low	123 Å²	123	162.5 Å²	162.5	86%	0.86	83%	0.834	S	S	*	*	P	Polyproline II helix	trans	-63.9	125	-172.4	56.2	0	0	0	0	114.4
683	V	29.5	Very low	28.4	Very low	141 Å²	141	167.6 Å²	167.6	86%	0.855	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-81.7	127	167	177.4	0	0	0	0	110.4	P681	P681-V683 PolarHBondContact O-N 3.18Å
684	R	26.3	Very low	28	Very low	236 Å²	236	166.8 Å²	166.8	89%	0.891	84%	0.842	S	S	*	*	P	Polyproline II helix	trans	-77.6	127.3	176.8	-162.3	179.5	-161.9	177	5.3	110.1
685	K	29.9	Very low	27.7	Very low	198 Å²	198	171.8 Å²	171.8	86%	0.861	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-68.3	138.5	176.8	-67.7	179.4	177	179.3	0	111.9
686	V	27.8	Very low	27.4	Very low	134 Å²	134	172.2 Å²	172.2	81%	0.812	84%	0.841	S	S	*	*			trans	-137.5	147.1	149.5	-177	0	0	0	0	108.3
687	W	23.6	Very low	27.4	Very low	235 Å²	235	172.6 Å²	172.6	89%	0.89	84%	0.838	S	S	*	*			trans	-69.5	161.4	-179.1	-87.7	63.7	0	0	0	113.5
688	F	25	Very low	27.3	Very low	203 Å²	203	170.1 Å²	170.1	89%	0.89	83%	0.831	S	S	*	*			trans	-120	134.6	160.3	-91.2	-85.3	0	0	0	110.1
689	E	25.8	Very low	27.2	Very low	182 Å²	182	170.3 Å²	170.3	85%	0.85	83%	0.829	S	S	*	*			trans	-113.9	143.7	169.5	-167.9	163.3	-160.1	0	0	107.6
690	P	33.8	Very low	27.1	Very low	120 Å²	120	167 Å²	167	78%	0.779	82%	0.817	S	S	*	*			trans	-100.5	128	-163.6	35.4	-30.5	0	0	0	113.5
691	E	27.8	Very low	26.9	Very low	198 Å²	198	168.5 Å²	168.5	93%	0.925	82%	0.815	S	S	*	*			trans	-134.2	143.2	159	-77.3	-152.9	140.6	0	0	112.7
692	H	28.3	Very low	26.8	Very low	185 Å²	185	167.5 Å²	167.5	86%	0.856	81%	0.811	S	S	*	*			trans	-78.6	135.8	172.2	-77.2	-77.7	0	0	0	111.4
693	K	27.9	Very low	26.8	Very low	211 Å²	211	168 Å²	168	92%	0.917	81%	0.809	S	S	*	*				-168.1	152.2	124.5	-105.2	155.1	-171.2	171.3	0	113.9
694	V	27	Very low	26.6	Very low	113 Å²	113	172.2 Å²	172.2	69%	0.685	81%	0.81	S	S	*	*			trans	-77.7	145.7	174.3	170.2	0	0	0	0	109.9
695	Y	27.9	Very low	27.3	Very low	222 Å²	222	166 Å²	166	87%	0.871	80%	0.8	S	S	*	*				-175	171.7	128.5	-95.5	-60.9	0	0	0	112
696	T	24.1	Very low	27.1	Very low	105 Å²	105	160.9 Å²	160.9	64%	0.644	79%	0.789	S	S	*	*			trans	-127.7	162.4	-153.4	50.3	0	0	0	0	114.6
697	Y	25.4	Very low	27.1	Very low	215 Å²	215	161.3 Å²	161.3	84%	0.843	79%	0.787	S	S	*	*			trans	86.2	146.4	154.4	-90.4	-71.4	0	0	0	121.5
698	D	24.9	Very low	27.3	Very low	132 Å²	132	155.3 Å²	155.3	71%	0.706	78%	0.781	S	S	*	*			trans	-65.8	152.9	-176.6	-50.9	-80	0	0	0	115
699	K	25.3	Very low	27.5	Very low	186 Å²	186	149.9 Å²	149.9	81%	0.809	77%	0.773	S	S	*	*				176.3	152.9	98.8	-101.7	-178.3	179.7	175.3	0	115.4
700	N	24.8	Very low	27.6	Very low	120 Å²	120	145.5 Å²	145.5	64%	0.642	77%	0.768	S	S	*	*			trans	78.6	135.3	144.4	-85.2	31	0	0	0	123.3
701	E	25.5	Very low	27.2	Very low	157 Å²	157	147.5 Å²	147.5	73%	0.734	77%	0.771	S	S	*	*			trans	81.3	114.4	136.3	-77.5	170.9	120	0	0	122.4
702	S	24.5	Very low	27.2	Very low	102 Å²	102	145.1 Å²	145.1	71%	0.713	76%	0.764	S	S	*	*			trans	61.4	146.2	134.1	71.5	0	0	0	0	118.8
703	T	27.5	Very low	27.1	Very low	132 Å²	132	142.9 Å²	142.9	81%	0.81	76%	0.758	S	S	*	*			cis	-154.3	152.5	27.1	-31.1	0	0	0	0	111
704	R	25	Very low	27.1	Very low	231 Å²	231	140.4 Å²	140.4	87%	0.872	75%	0.75	S	S	*	*			trans	-68.7	176.8	156.5	-87.2	-175.1	-179.5	-179.5	0.6	109.9
705	P	40.8	Very low	27	Very low	106 Å²	106	140 Å²	140	69%	0.688	75%	0.753	S	S	*	*			cis	-146.2	-166.9	23.4	38.1	-14.3	0	0	0	117.1
706	S	26.3	Very low	26.9	Very low	90 Å²	90	136 Å²	136	63%	0.629	75%	0.746	S	S	*	*			trans	69.1	142.2	143.7	57.5	0	0	0	0	119.8
707	D	27.7	Very low	27	Very low	143 Å²	143	138.6 Å²	138.6	77%	0.765	75%	0.751	S	S	*	*			cis	-165.4	161.4	-12	-108.7	-32.3	0	0	0	110
708	S	28.7	Very low	26.9	Very low	109 Å²	109	139.9 Å²	139.9	76%	0.762	75%	0.754	S	S	*	*			trans	50.7	150.9	141.4	-63.5	0	0	0	0	122.3
709	A	28.1	Very low	27	Very low	88 Å²	88	137.8 Å²	137.8	73%	0.727	76%	0.755	S	S	*	*			cis	-173.2	174	-16	0	0	0	0	0	109.2
710	A	27.4	Very low	26.9	Very low	91 Å²	91	137.2 Å²	137.2	75%	0.752	76%	0.761	S	S	*	*			trans	68.7	131	166.4	0	0	0	0	0	117.6
711	L	27.1	Very low	26.9	Very low	162 Å²	162	135.4 Å²	135.4	85%	0.848	77%	0.77	S	S	*	*			cis	112.8	150.6	18	-84.5	169.1	0	0	0	112.9
712	L	26.9	Very low	26.9	Very low	147 Å²	147	137.3 Å²	137.3	77%	0.77	78%	0.779	S	S	*	*			trans	91	108.7	175.9	-52.4	174.2	0	0	0	113.9
713	D	26.1	Very low	26.8	Very low	138 Å²	138	138.3 Å²	138.3	74%	0.738	79%	0.786	S	S	*	*				78.8	138.9	66.1	-84.8	-18.9	0	0	0	112.9
714	E	27.9	Very low	26.8	Very low	159 Å²	159	139 Å²	139	74%	0.743	78%	0.78	S	S	*	*			cis	-161.2	161.2	-9.3	-155.4	-155.6	133.6	0	0	109
715	S	25	Very low	26.7	Very low	106 Å²	106	137.3 Å²	137.3	74%	0.741	77%	0.774	S	S	*	*			trans	67.4	171	153.1	82.1	0	0	0	0	120.3
716	N	25.2	Very low	25.9	Very low	138 Å²	138	141 Å²	141	74%	0.738	78%	0.782	S	S	*	*				-160.7	164	-58.5	-159.7	-9.4	0	0	0	110
717	Q	26.1	Very low	26	Very low	159 Å²	159	145.9 Å²	145.9	74%	0.743	79%	0.792	S	S	*	*			trans	76.6	111.4	159.4	-54.9	-172.7	10	0	0	123.5
718	R	24.2	Very low	26	Very low	242 Å²	242	145.2 Å²	145.2	91%	0.913	80%	0.795	S	S	*	*				30.3	130.1	124.1	-67.2	178.9	171.4	168.2	-2.4	121.6
719	A	25.7	Very low	25.9	Very low	87 Å²	87	145.7 Å²	145.7	72%	0.719	79%	0.794	S	S	*	*				160.3	144.2	93.5	0	0	0	0	0	115.1
720	D	24.6	Very low	25.8	Very low	175 Å²	175	153 Å²	153	94%	0.936	80%	0.802	S	S	*	*			trans	47.3	146.9	148.3	-57.9	-17.4	0	0	0	125.2
721	G	25	Very low	25.8	Very low	81 Å²	81	153.5 Å²	153.5	84%	0.835	80%	0.8	S	S	*	*			trans	136.3	106.5	147.1	0	0	0	0	0	118.3
722	Q	24.4	Very low	25.7	Very low	197 Å²	197	153.8 Å²	153.8	92%	0.921	80%	0.801	S	S	*	*			trans	-75.5	148.2	-176	-62.3	164.2	-65.6	0	0	117.3
723	S	23.5	Very low	25.9	Very low	123 Å²	123	151.5 Å²	151.5	86%	0.86	80%	0.797	S	S	*	*			trans	161.9	155.8	136.8	-94.9	0	0	0	0	111.2
724	E	25.9	Very low	26	Very low	146 Å²	146	152 Å²	152	68%	0.682	80%	0.8	S	S	*	*			cis	-152.6	-167.1	-22.3	-155.4	-140.8	149.4	0	0	107.9
725	R	23.7	Very low	26.6	Very low	197 Å²	197	150 Å²	150	74%	0.743	80%	0.8	S	S	*	*			trans	23.5	119.9	150.5	-97.3	173.1	-153.8	-154.1	-1.7	121.4
726	E	25.3	Very low	26.4	Very low	183 Å²	183	148.2 Å²	148.2	86%	0.855	80%	0.8	S	S	*	*				-178.9	178.9	86.4	-115.3	-179.1	-174.3	0	0	113.8
727	K	26.4	Very low	27.3	Very low	193 Å²	193	147.2 Å²	147.2	84%	0.839	80%	0.801	S	S	*	*			trans	-78.8	162.9	-175.1	-58.5	168.1	179.3	170	0	113.2
728	P	29.3	Very low	27.4	Very low	129 Å²	129	146.8 Å²	146.8	84%	0.838	80%	0.803	S	S	*	*			trans	-112.6	144.2	155.3	35.8	-26.9	0	0	0	114
729	T	25.5	Very low	27.5	Very low	119 Å²	119	144 Å²	144	73%	0.73	80%	0.801	S	S	*	*			trans	-135.3	139	170.6	-35.5	0	0	0	0	108.7
730	R	26.8	Very low	27.6	Very low	240 Å²	240	149 Å²	149	91%	0.906	81%	0.809	S	S	*	*			trans	179.4	132.5	155.6	-103.9	164.2	179.2	-174.9	-1	108.3
731	C	27	Very low	27.7	Very low	103 Å²	103	144.4 Å²	144.4	70%	0.696	80%	0.803	S	S	*	*			cis	87.7	119.1	26.5	-58.3	0	0	0	0	116
732	L	26	Very low	27.7	Very low	168 Å²	168	146.1 Å²	146.1	88%	0.88	80%	0.802	S	S	*	*			trans	-175.9	107	148.6	-97.6	135.9	0	0	0	105.3
733	S	29.3	Very low	27.8	Very low	98 Å²	98	141.3 Å²	141.3	69%	0.685	79%	0.789	S	S	*	*				72.7	135.4	71.5	-59.4	0	0	0	0	112.3
734	D	28.8	Very low	27.9	Very low	149 Å²	149	144.8 Å²	144.8	80%	0.797	79%	0.789	S	S	*	*			cis	-168.3	-170.3	6.1	-123.3	-19.6	0	0	0	108.4
735	P	40	Very low	28	Very low	116 Å²	116	145.2 Å²	145.2	75%	0.753	80%	0.795	S	S	*	*			cis	-132	-179.1	-13.9	35	-13.7	0	0	0	115.8
736	G	22.4	Very low	28.9	Very low	70 Å²	70	141.1 Å²	141.1	72%	0.722	79%	0.794	S	S	*	*			trans	-99.8	-148.7	170.2	0	0	0	0	0	114
737	P	44.3	Very low	29.2	Very low	117 Å²	117	141.9 Å²	141.9	76%	0.76	82%	0.82	S	S	*	*			cis	-122.6	-174.8	1.2	28.1	-2.1	0	0	0	113.2
738	D	26.4	Very low	29.4	Very low	150 Å²	150	139.3 Å²	139.3	80%	0.802	82%	0.819	S	S	*	*				-166	169.3	85.3	-80.5	-25.1	0	0	0	113.5
739	E	27.8	Very low	29.4	Very low	184 Å²	184	139.8 Å²	139.8	86%	0.86	82%	0.818	S	S	*	*			trans	-73.2	171.1	-175.5	-51.5	-175.3	137.7	0	0	112.9
740	E	27.3	Very low	29.6	Very low	192 Å²	192	141 Å²	141	90%	0.897	82%	0.823	S	S	*	*			cis	-142.3	161.5	27.3	-55.7	169.7	131.9	0	0	109
741	G	26	Very low	29.7	Very low	78 Å²	78	135.2 Å²	135.2	80%	0.804	82%	0.818	S	S	*	*				137.6	122.9	68.4	0	0	0	0	0	110.9
742	S	25.4	Very low	29.9	Very low	117 Å²	117	137.2 Å²	137.2	82%	0.818	83%	0.825	S	S	*	*			trans	-64.4	164.3	175.7	53.9	0	0	0	0	113
743	C	27	Very low	30.2	Very low	96 Å²	96	135.1 Å²	135.1	65%	0.649	82%	0.822	S	S	*	*			cis	177.9	154.6	48.9	-149.9	0	0	0	0	106.3
744	F	25.1	Very low	30.2	Very low	195 Å²	195	137.8 Å²	137.8	86%	0.855	83%	0.831	S	S	*	*				-177.6	159.5	65.7	-106.5	-78.9	0	0	0	110.4
745	L	28.8	Very low	30.3	Very low	155 Å²	155	136.9 Å²	136.9	81%	0.812	83%	0.834	S	S	*	*			trans	-115.5	176.4	162.1	-82.2	164.6	0	0	0	108.2
746	P	42.9	Very low	29.5	Very low	111 Å²	111	138.7 Å²	138.7	72%	0.721	84%	0.841	S	S	*	*			cis	-130.8	-176.5	-38.1	37.2	-20.9	0	0	0	112.2
747	S	31	Very low	30.2	Very low	199 Å²	199	144.9 Å²	144.9	100%	1.392	85%	0.852	S	S	*	*			trans	-151.9	0	150.1	-69.5	0	0	0	0	109.4

Retrieved 747 of 747 residues in 746.2 ms (Link to these results)

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