A0A087XG09_POEFO Loading...

Urocanate hydratase

AlphaFold DB , UniProt , Accession A0A087XG09, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 675 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M47.1Very low84.7Confident245 Ų24563.8 Ų63.8100%1.20735%0.354SS*.  0131.10-71.8-179.9-116.800106.3
2S61.2Low85.5Confident41 Ų4162.1 Ų62.129%0.28735%0.348SS..  trans-62.6140.7177.637.70000111D6 V83S2-D6 WeakPolarHBondContact CA-OD2 3.46Å; S2-D6 WeakPolarHBondContact CB-OD2 3.27Å; S2-V83 WeakPolarHBondContact OG-CA 3.48Å; S2-V83 PolarHBondContact OG-N 2.68Å; S2-V83 VanDerWaalsContact OG-N 3.11Å
3D82.1Confident86.3Confident80 Ų8060 Ų6043%0.42834%0.336SS..  trans-84151.5-179.9-173.3-8.1000109.3K5 D6D3-K5 HydrophobicContact CB-CB 4.3Å; D3-K5 PolarHBondContact O-N 2.97Å; D3-K5 PolarHBondContact OD1-N 2.92Å; D3-K5 VanDerWaalsContact OD2-CD 3.28Å; D3-K5 WeakPolarHBondContact OD2-CD 2.95Å; D3-K5 WeakPolarHBondContact OD2-CG 3.36Å; D3-D6 PolarHBondContact N-OD2 3.08Å; D3-D6 VanDerWaalsContact O-CB 3.26Å; D3-D6 WeakPolarHBondContact O-CB 3.36Å; D3-D6 PolarHBondContact O-N 2.87Å
4L92.2Very high86.6Confident9 Ų965.9 Ų65.95%0.04737%0.366CS..G310 helixtrans-57.9-25.2170.8-72.2176.9000111.8D6 L7 V83 Y88 Q92 Y93 M108L4-D6 PolarHBondContact O-N 3.21Å; L4-L7 HydrophobicContact CD2-CD1 4.07Å; L4-L7 VanDerWaalsContact O-CB 3.31Å; L4-L7 WeakPolarHBondContact O-CB 3.47Å; L4-L7 PolarHBondContact O-N 3.15Å; L4-V83 HydrophobicContact CD2-CG2 4.27Å; L4-Y88 HydrophobicContact CD1-CD1 4.27Å; L4-Y88 HydrophobicContact CD1-CD2 4.12Å; L4-Y88 HydrophobicContact CD1-CG 3.86Å; L4-Y88 HydrophobicContact CD2-CD2 3.82Å; L4-Y88 HydrophobicContact CD2-CE2 3.88Å; L4-Y88 HydrophobicContact CD2-CG 4.36Å; L4-Y88 HydrophobicContact CG-CD2 4.46Å; L4-Q92 HydrophobicContact CD1-CB 3.79Å; L4-Q92 WeakPolarHBondContact CD1-O 3.21Å; L4-Y93 HydrophobicContact CD1-CD1 4.37Å; L4-Y93 HydrophobicContact CD1-CE1 4.33Å; L4-Y93 HydrophobicContact CD2-CE1 4.47Å; L4-M108 HydrophobicContact CD2-CE 3.89Å; L4-M108 HydrophobicContact CD2-SD 4Å
5K91.6Very high86.9Confident133 Ų13369.3 Ų69.358%0.57839%0.392SS*.G310 helixtrans-55.9-28.3170.7-66.8-176.8-170.71710113.6D3 L7 C8 P94D3-K5 HydrophobicContact CB-CB 4.3Å; D3-K5 PolarHBondContact O-N 2.97Å; D3-K5 PolarHBondContact OD1-N 2.92Å; D3-K5 VanDerWaalsContact OD2-CD 3.28Å; D3-K5 WeakPolarHBondContact OD2-CD 2.95Å; D3-K5 WeakPolarHBondContact OD2-CG 3.36Å; K5-L7 PolarHBondContact O-N 3.39Å; K5-C8 WeakPolarHBondContact O-CB 3.33Å; K5-C8 PolarHBondContact O-N 3.3Å; K5-P94 HydrophobicContact CG-CB 4.3Å; K5-P94 HydrophobicContact CG-CG 4.02Å
6D90.4Very high87.5Confident87 Ų8767.1 Ų67.147%0.46538%0.379SS..G310 helixtrans-64.2-22.1177-65.6-18.1000112.2S2 D3 L4 C8 R139S2-D6 WeakPolarHBondContact CA-OD2 3.46Å; S2-D6 WeakPolarHBondContact CB-OD2 3.27Å; D3-D6 PolarHBondContact N-OD2 3.08Å; D3-D6 VanDerWaalsContact O-CB 3.26Å; D3-D6 WeakPolarHBondContact O-CB 3.36Å; D3-D6 PolarHBondContact O-N 2.87Å; L4-D6 PolarHBondContact O-N 3.21Å; D6-C8 VanDerWaalsContact C-N 3.32Å; D6-R139 PolarHBondContact O-NH1 3.3Å; D6-R139 VanDerWaalsContact O-NH1 3.15Å
7L91.3Very high87.9Confident1 Ų164.7 Ų64.71%0.00537%0.367CS..G310 helixtrans-77.3-21.1176.6-58.6-176.5000112.4L4 K5 P81 V83 M104 M108 F138 M142L4-L7 HydrophobicContact CD2-CD1 4.07Å; L4-L7 VanDerWaalsContact O-CB 3.31Å; L4-L7 WeakPolarHBondContact O-CB 3.47Å; L4-L7 PolarHBondContact O-N 3.15Å; K5-L7 PolarHBondContact O-N 3.39Å; L7-P81 HydrophobicContact CD2-CB 3.76Å; L7-P81 HydrophobicContact CD2-CG 4.16Å; L7-V83 HydrophobicContact CD1-CG1 4.1Å; L7-V83 HydrophobicContact CD2-CG1 3.89Å; L7-V83 HydrophobicContact CG-CG1 4.22Å; L7-M104 HydrophobicContact CB-CE 4.45Å; L7-M108 HydrophobicContact CD1-CE 3.91Å; L7-M108 HydrophobicContact CD1-SD 3.75Å; L7-F138 HydrophobicContact CD1-CZ 4.46Å; L7-F138 HydrophobicContact CD2-CE1 3.95Å; L7-F138 HydrophobicContact CD2-CZ 4.33Å; L7-M142 HydrophobicContact CB-CB 4.04Å; L7-M142 HydrophobicContact CB-CG 4.46Å; L7-M142 HydrophobicContact CD1-CE 3.69Å; L7-M142 WeakPolarHBondContact O-CB 3.22Å
8C93.4Very high88.2Confident25 Ų2565.8 Ų65.817%0.16938%0.377CS..THydrogen-bonded Turntrans-83.7-19.1-174.8-56.10000113K5 D6 G10 P94 R143 S146K5-C8 WeakPolarHBondContact O-CB 3.33Å; K5-C8 PolarHBondContact O-N 3.3Å; D6-C8 VanDerWaalsContact C-N 3.32Å; C8-G10 PolarHBondContact O-N 2.75Å; C8-P94 WeakPolarHBondContact SG-CG 3.45Å; C8-R143 WeakPolarHBondContact O-CB 3.46Å; C8-R143 WeakPolarHBondContact O-CG 3.31Å; C8-S146 WeakPolarHBondContact CB-OG 3.39Å; C8-S146 WeakPolarHBondContact SG-CB 3.46Å
9G92.1Very high88.4Confident56 Ų5665.9 Ų65.958%0.57738%0.376SS*.THydrogen-bonded Turntrans-70.6-10.6178.100000114.7
10G93.6Very high88.5Confident1 Ų171.1 Ų71.11%0.0139%0.389CS..  trans75.1-134.6-175.300000112.2C8 P12C8-G10 PolarHBondContact O-N 2.75Å; G10-P12 VanDerWaalsContact O-CD 3.3Å; G10-P12 WeakPolarHBondContact O-CD 3.33Å
11L96.4Very high88.7Confident24 Ų2468.9 Ų68.913%0.12638%0.383CS..SBendtrans-78.8119.5-179.3-65.9171.5000110.7L13 Y51 F52 F79 A136 R139 L140L11-L13 HydrophobicContact CB-CD1 4.47Å; L11-L13 HydrophobicContact CB-CD2 4.09Å; L11-L13 HydrophobicContact CB-CG 4.1Å; L11-L13 PolarHBondContact O-N 2.72Å; L11-Y51 WeakPolarHBondContact CD1-O 3.42Å; L11-F52 HydrophobicContact CD1-CD1 4.28Å; L11-F52 HydrophobicContact CD1-CE1 4.03Å; L11-F52 HydrophobicContact CD2-CE1 4.16Å; L11-F79 HydrophobicContact CD2-CD1 4.1Å; L11-F79 HydrophobicContact CD2-CG 4.47Å; L11-A136 HydrophobicContact CD2-CB 3.74Å; L11-R139 HydrophobicContact CD2-CB 3.87Å; L11-R139 HydrophobicContact CD2-CG 4.32Å; L11-L140 HydrophobicContact CD1-CD1 4.4Å; L11-L140 HydrophobicContact CD1-CD2 4.24Å; L11-L140 HydrophobicContact CD1-CG 4.31Å; L11-L140 HydrophobicContact CG-CD2 4.2Å; L11-L140 HydrophobicContact CG-CG 4.27Å
12P94.9Very high90.8Very high43 Ų4359.8 Ų59.828%0.27934%0.335SS..  trans-73.3114.6168.929.3-34.3000109.9G10 P17 F79G10-P12 VanDerWaalsContact O-CD 3.3Å; G10-P12 WeakPolarHBondContact O-CD 3.33Å; P12-P17 HydrophobicContact CB-CG 4.49Å; P12-P17 HydrophobicContact CG-CB 4.42Å; P12-P17 HydrophobicContact CG-CG 3.81Å; P12-P17 VanDerWaalsContact O-CD 3.24Å; P12-P17 WeakPolarHBondContact O-CD 3.37Å; P12-F79 HydrophobicContact CG-CD1 4.23Å
13L95Very high92.3Very high35 Ų3560.7 Ų60.718%0.18334%0.337CS..  trans-115.9-35.2-173.1-63.5176.1000113.5L11 P15 L16 F52 P53 H56L11-L13 HydrophobicContact CB-CD1 4.47Å; L11-L13 HydrophobicContact CB-CD2 4.09Å; L11-L13 HydrophobicContact CB-CG 4.1Å; L11-L13 PolarHBondContact O-N 2.72Å; L13-P15 VanDerWaalsContact C-C 3.47Å; L13-P15 CarbonylContact O-C 3.58Å; L13-L16 HydrophobicContact CD2-CD2 4.22Å; L13-L16 PolarHBondContact O-N 2.97Å; L13-F52 HydrophobicContact CD2-CD1 3.76Å; L13-F52 HydrophobicContact CD2-CE1 4.36Å; L13-P53 HydrophobicContact CD1-CG 3.73Å; L13-H56 PolarHBondContact O-CE1 3.34Å
14D90.5Very high92.7Very high142 Ų14262.3 Ų62.376%0.75935%0.352SS*.SBendtrans-129.1100.8-175.9-69.5-49.1000111.9H56D14-H56 IonicContact OD1-CE1 2.73Å; D14-H56 PolarHBondContact OD1-CE1 2.94Å; D14-H56 IonicContact OD1-NE2 2.8Å
15P92.3Very high92.5Very high117 Ų11768.7 Ų68.776%0.7639%0.386SS*.SBendcis-73.6157.9-8.932.7-35000112.2L13L13-P15 VanDerWaalsContact C-C 3.47Å; L13-P15 CarbonylContact O-C 3.58Å
16L95.3Very high92.3Very high34 Ų3463.8 Ų63.818%0.17837%0.367CS..PPolyproline II helixtrans-57.5136.5167.8-74.7173.8000109.3L13 H56 T59 L60 F79L13-L16 HydrophobicContact CD2-CD2 4.22Å; L13-L16 PolarHBondContact O-N 2.97Å; L16-H56 HydrophobicContact CD1-CB 4.27Å; L16-T59 HydrophobicContact CD1-CG2 4.45Å; L16-L60 HydrophobicContact CD1-CD2 4.41Å; L16-F79 HydrophobicContact CD2-CE1 4.29Å; L16-F79 HydrophobicContact CD2-CZ 4.02Å
17P94.4Very high92Very high27 Ų2763.2 Ų63.218%0.17537%0.368CS..PPolyproline II helixtrans-64.6153.7177.130.2-37.1000109.9P12 N19 R78 F79P12-P17 HydrophobicContact CB-CG 4.49Å; P12-P17 HydrophobicContact CG-CB 4.42Å; P12-P17 HydrophobicContact CG-CG 3.81Å; P12-P17 VanDerWaalsContact O-CD 3.24Å; P12-P17 WeakPolarHBondContact O-CD 3.37Å; P17-N19 PolarHBondContact O-N 3.46Å; P17-R78 HydrophobicContact CG-CG 3.76Å; P17-R78 WeakPolarHBondContact CG-O 3.39Å; P17-R78 WeakPolarHBondContact O-CG 3.41Å; P17-R78 PolarHBondContact O-NH1 2.78Å; P17-F79 HydrophobicContact CG-CD1 4.26Å; P17-F79 HydrophobicContact CG-CE1 4.32Å
18P93.4Very high91.8Very high85 Ų8565.3 Ų65.355%0.55238%0.377SS*.PPolyproline II helixtrans-60.4137.8177.226.1-34.3000110.7R20P18-R20 PolarHBondContact O-N 3.11Å
19N93.3Very high91.4Very high67 Ų6764.4 Ų64.436%0.35837%0.372SS..  trans-75.6111.2172.1-176.3-3000109.2P17 G21 E63 R78P17-N19 PolarHBondContact O-N 3.46Å; N19-G21 PolarHBondContact OD1-N 2.98Å; N19-E63 PolarHBondContact ND2-OE1 3.5Å; N19-E63 PolarHBondContact ND2-OE2 2.97Å; N19-R78 HydrophobicContact CB-CB 4.33Å
20R90.4Very high90.9Very high170 Ų17065.2 Ų65.264%0.64237%0.367SS*.  trans-91.6-10.6-179.4-61.6179.7-174.7-179.20113.1P18P18-R20 PolarHBondContact O-N 3.11Å
21G90.8Very high90.5Very high25 Ų2569.3 Ų69.326%0.25839%0.392SS..  trans56.7-151.9-172.500000112.9N19N19-G21 PolarHBondContact OD1-N 2.98Å
22R92.9Very high89.7Confident54 Ų5469.6 Ų69.620%0.20439%0.391CS..  trans-80.6137.3177-75.8-174.6177-165.4-5.9111.4P24 H28 Y71 Y77 E121R22-P24 WeakPolarHBondContact O-CD 3.35Å; R22-H28 VanDerWaalsContact CB-CE1 3.42Å; R22-H28 WeakPolarHBondContact CB-CE1 3.28Å; R22-H28 VanDerWaalsContact CG-CE1 3.41Å; R22-H28 WeakPolarHBondContact CG-CE1 3.37Å; R22-Y71 VanDerWaalsContact CZ-CE1 3.44Å; R22-Y77 HydrophobicContact CG-CE1 4.04Å; R22-Y77 HydrophobicContact CG-CE2 4.17Å; R22-Y77 PolarHBondContact NE-OH 2.91Å; R22-Y77 PolarHBondContact NH2-OH 2.74Å; R22-E121 IonicContact CZ-OE1 3.76Å; R22-E121 IonicContact NE-OE1 2.72Å; R22-E121 PolarHBondContact NE-OE1 3.06Å; R22-E121 IonicContact NH2-OE1 3.37Å
23D92.4Very high89Confident60 Ų6071.6 Ų71.632%0.32140%0.403SS..  trans-84.5112.4170.9179.5-3.6000109.6N25 V26 H28 Q120D23-N25 PolarHBondContact O-N 3.19Å; D23-N25 WeakPolarHBondContact OD1-CB 3.18Å; D23-N25 PolarHBondContact OD1-N 3.43Å; D23-N25 PolarHBondContact OD1-ND2 2.91Å; D23-V26 HydrophobicContact CB-CG2 4.18Å; D23-V26 WeakPolarHBondContact O-CG2 3.47Å; D23-V26 PolarHBondContact O-N 3.41Å; D23-V26 VanDerWaalsContact O-N 3.15Å; D23-H28 PolarHBondContact O-NE2 2.73Å; D23-Q120 VanDerWaalsContact CB-NE2 3.27Å
24P89.4Confident88.4Confident114 Ų11470.7 Ų70.774%0.7440%0.399SS*.THydrogen-bonded Turntrans-64-10.6-176.628.9-36.6000114R22R22-P24 WeakPolarHBondContact O-CD 3.35Å
25N88.5Confident88.2Confident143 Ų14370.1 Ų70.177%0.76540%0.396SS*.THydrogen-bonded Turntrans-89-3.7-179.9-54.4-68.2000113.7D23D23-N25 PolarHBondContact O-N 3.19Å; D23-N25 WeakPolarHBondContact OD1-CB 3.18Å; D23-N25 PolarHBondContact OD1-N 3.43Å; D23-N25 PolarHBondContact OD1-ND2 2.91Å
26V87.7Confident88.2Confident29 Ų2965.6 Ų65.618%0.17637%0.365CS..SBendtrans-112.3149.2174.2-57.90000111D23 H28 P119 Q120D23-V26 HydrophobicContact CB-CG2 4.18Å; D23-V26 WeakPolarHBondContact O-CG2 3.47Å; D23-V26 PolarHBondContact O-N 3.41Å; D23-V26 VanDerWaalsContact O-N 3.15Å; V26-H28 PolarHBondContact O-CD2 3.23Å; V26-P119 HydrophobicContact CB-CG 4.36Å; V26-Q120 HydrophobicContact CG2-CG 3.99Å
27P84.3Confident88.2Confident75 Ų7571.5 Ų71.549%0.48739%0.385SS..  trans-64.1141.7173.627.5-35.4000110.7Q117 F118P27-Q117 VanDerWaalsContact CG-O 3.28Å; P27-Q117 WeakPolarHBondContact CG-O 3.38Å; P27-F118 HydrophobicContact CB-CD1 4.1Å; P27-F118 HydrophobicContact CB-CE1 4.35Å
28H86.1Confident88.3Confident45 Ų4573.5 Ų73.521%0.20840%0.404CS..  trans-119146.7-178.7-76-72.6000112.7R22 D23 V26 F118 Q120 E121R22-H28 VanDerWaalsContact CB-CE1 3.42Å; R22-H28 WeakPolarHBondContact CB-CE1 3.28Å; R22-H28 VanDerWaalsContact CG-CE1 3.41Å; R22-H28 WeakPolarHBondContact CG-CE1 3.37Å; D23-H28 PolarHBondContact O-NE2 2.73Å; V26-H28 PolarHBondContact O-CD2 3.23Å; H28-F118 WeakPolarHBondContact O-CD1 3.21Å; H28-F118 WeakPolarHBondContact O-CE1 3.34Å; H28-Q120 PolarHBondContact CE1-OE1 3.02Å; H28-E121 WeakPolarHBondContact CA-OE2 3.41Å; H28-E121 IonicContact CE1-OE1 2.69Å; H28-E121 IonicContact CG-OE1 2.68Å; H28-E121 IonicContact CG-OE2 3.58Å; H28-E121 IonicContact ND1-OE1 3.54Å; H28-E121 PolarHBondContact ND1-OE1 3.32Å; H28-E121 IonicContact ND1-OE2 2.96Å; H28-E121 PolarHBondContact ND1-OE2 3.32Å
29A85.6Confident88.5Confident6 Ų676.3 Ų76.35%0.0541%0.41CS..PPolyproline II helixtrans-63.4145.5174.500000111.2F118 E121A29-F118 HydrophobicContact CB-CB 4.1Å; A29-F118 HydrophobicContact CB-CD2 3.54Å; A29-F118 HydrophobicContact CB-CE2 4.04Å; A29-F118 HydrophobicContact CB-CG 3.86Å; A29-F118 VanDerWaalsContact N-CG 3.33Å; A29-E121 HydrophobicContact CB-CB 3.96Å; A29-E121 HydrophobicContact CB-CG 3.84Å; A29-E121 PolarHBondContact N-OE2 3.16Å
30P81.4Confident88.7Confident73 Ų7374.3 Ų74.347%0.47440%0.398SS..PPolyproline II helixtrans-53.2148.5171.2-24.833.6000112.1R32P30-R32 PolarHBondContact O-N 3.14Å
31V85.4Confident89.1Confident88 Ų8870 Ų7053%0.53339%0.385SS..PPolyproline II helixtrans-63.5133.1173.5176.60000108.8Q70V31-Q70 WeakPolarHBondContact CG1-O 3.32Å
32R80.1Confident89.4Confident29 Ų2977.5 Ų77.511%0.10941%0.406CS..PPolyproline II helixtrans-94.6152.2177.5-62.1-165.9-178.6-148.721.8111.5P30 P34 Y71 G72 Y191 E192 F195P30-R32 PolarHBondContact O-N 3.14Å; R32-P34 WeakPolarHBondContact O-CD 3.33Å; R32-Y71 PolarHBondContact N-O 3.37Å; R32-G72 VanDerWaalsContact O-CA 3.24Å; R32-G72 WeakPolarHBondContact O-CA 3.48Å; R32-Y191 PolarHBondContact NH1-OH 3Å; R32-Y191 VanDerWaalsContact NH1-OH 3.11Å; R32-Y191 PolarHBondContact NH2-OH 3.17Å; R32-E192 IonicContact CZ-OE2 2.86Å; R32-E192 IonicContact NH1-OE1 3.06Å; R32-E192 PolarHBondContact NH1-OE1 3.35Å; R32-E192 IonicContact NH1-OE2 2.7Å; R32-E192 PolarHBondContact NH1-OE2 2.63Å; R32-F195 VanDerWaalsContact CZ-CE1 3.45Å
33T80Confident89.7Confident85 Ų8578 Ų7852%0.52141%0.412SS..  trans-126.274.4178.354.80000109.9N35T33-N35 PolarHBondContact O-N 3.39Å; T33-N35 VanDerWaalsContact O-N 3.12Å
34P81.4Confident90Very high17 Ų1775.1 Ų75.111%0.1140%0.397CS..  trans-69.4-6.3-175.129.7-38000114.3R32 L36 A196R32-P34 WeakPolarHBondContact O-CD 3.33Å; P34-L36 VanDerWaalsContact C-N 3.29Å; P34-L36 HydrophobicContact CB-CD2 4.12Å; P34-L36 HydrophobicContact CB-CG 4.05Å; P34-L36 HydrophobicContact CG-CD1 4.45Å; P34-L36 HydrophobicContact CG-CG 3.95Å; P34-L36 PolarHBondContact O-N 2.89Å; P34-A196 HydrophobicContact CB-CB 3.57Å; P34-A196 HydrophobicContact CG-CB 3.62Å
35N86.4Confident90.4Very high129 Ų12971.5 Ų71.569%0.6937%0.371SS*.  trans49.447.5-179.3-62.1-32.5000112.6T33T33-N35 PolarHBondContact O-N 3.39Å; T33-N35 VanDerWaalsContact O-N 3.12Å
36L93.1Very high90.9Very high23 Ų2372.6 Ų72.612%0.1236%0.364CS..  trans-69.5141178.2-62.3-173.4000111P34 E40 E41 A44 L68 R193 A196P34-L36 VanDerWaalsContact C-N 3.29Å; P34-L36 HydrophobicContact CB-CD2 4.12Å; P34-L36 HydrophobicContact CB-CG 4.05Å; P34-L36 HydrophobicContact CG-CD1 4.45Å; P34-L36 HydrophobicContact CG-CG 3.95Å; P34-L36 PolarHBondContact O-N 2.89Å; L36-E40 HydrophobicContact CB-CB 3.97Å; L36-E40 HydrophobicContact CD2-CB 4.13Å; L36-E40 HydrophobicContact CG-CB 4.44Å; L36-E41 HydrophobicContact CB-CG 3.92Å; L36-A44 HydrophobicContact CD1-CB 4.34Å; L36-L68 HydrophobicContact CD1-CD1 4.3Å; L36-L68 HydrophobicContact CD1-CD2 4.43Å; L36-R193 HydrophobicContact CD2-CB 4.34Å; L36-R193 HydrophobicContact CD2-CG 4.23Å; L36-A196 HydrophobicContact CD1-CB 3.96Å; L36-A196 HydrophobicContact CD2-CB 4.4Å; L36-A196 HydrophobicContact CG-CB 4.39Å
37R95.1Very high91.4Very high157 Ų15771.8 Ų71.859%0.59236%0.359SS*.  trans-72.9159.8167-62.5178.2-68.6160.40.8110E39 E40 E41R37-E39 PolarHBondContact O-N 3.4Å; R37-E39 VanDerWaalsContact O-N 3.1Å; R37-E40 HydrophobicContact CB-CG 4.42Å; R37-E40 WeakPolarHBondContact CB-OE2 3.44Å; R37-E40 IonicContact CZ-OE1 3.41Å; R37-E40 PolarHBondContact N-OE2 3.45Å; R37-E40 IonicContact NE-OE1 3.15Å; R37-E40 PolarHBondContact NE-OE1 3.24Å; R37-E40 VanDerWaalsContact NE-OE1 3.15Å; R37-E40 IonicContact NE-OE2 3.43Å; R37-E40 PolarHBondContact NE-OE2 3.44Å; R37-E40 IonicContact NH2-OE1 2.79Å; R37-E40 PolarHBondContact NH2-OE1 2.88Å; R37-E40 CarbonylContact O-C 3.56Å; R37-E40 WeakPolarHBondContact O-CA 3.42Å; R37-E40 WeakPolarHBondContact O-CB 3.42Å; R37-E40 PolarHBondContact O-N 3.47Å; R37-E41 PolarHBondContact O-N 2.99Å
38A96.4Very high92.1Very high69 Ų6968.6 Ų68.657%0.5734%0.339SS*.Hα-helixtrans-55.1-34.3179.300000113.7R42A38-R42 WeakPolarHBondContact O-CG 3.31Å; A38-R42 PolarHBondContact O-N 3.33Å
39E97.7Very high92.7Very high144 Ų14467.4 Ų67.467%0.67333%0.334SS*.Hα-helixtrans-69.3-36.3174.4-64.5-174.3162.900112.6R37 R42 L43R37-E39 PolarHBondContact O-N 3.4Å; R37-E39 VanDerWaalsContact O-N 3.1Å; E39-R42 PolarHBondContact O-N 3.24Å; E39-L43 WeakPolarHBondContact O-CB 3.3Å; E39-L43 PolarHBondContact O-N 3.2Å
40E97.9Very high93.4Very high26 Ų2674.5 Ų74.512%0.12136%0.36CS..Hα-helixtrans-73.2-36.6177.9-70.1163.5167.400111.1L36 R37 L43 A44 L197L36-E40 HydrophobicContact CB-CB 3.97Å; L36-E40 HydrophobicContact CD2-CB 4.13Å; L36-E40 HydrophobicContact CG-CB 4.44Å; R37-E40 HydrophobicContact CB-CG 4.42Å; R37-E40 WeakPolarHBondContact CB-OE2 3.44Å; R37-E40 IonicContact CZ-OE1 3.41Å; R37-E40 PolarHBondContact N-OE2 3.45Å; R37-E40 IonicContact NE-OE1 3.15Å; R37-E40 PolarHBondContact NE-OE1 3.24Å; R37-E40 VanDerWaalsContact NE-OE1 3.15Å; R37-E40 IonicContact NE-OE2 3.43Å; R37-E40 PolarHBondContact NE-OE2 3.44Å; R37-E40 IonicContact NH2-OE1 2.79Å; R37-E40 PolarHBondContact NH2-OE1 2.88Å; R37-E40 CarbonylContact O-C 3.56Å; R37-E40 WeakPolarHBondContact O-CA 3.42Å; R37-E40 WeakPolarHBondContact O-CB 3.42Å; R37-E40 PolarHBondContact O-N 3.47Å; E40-L43 CarbonylContact O-C 3.56Å; E40-L43 WeakPolarHBondContact O-CB 3.41Å; E40-L43 PolarHBondContact O-N 3.47Å; E40-A44 WeakPolarHBondContact O-CB 3.38Å; E40-A44 PolarHBondContact O-N 2.75Å; E40-L197 HydrophobicContact CB-CD2 4.13Å; E40-L197 WeakPolarHBondContact O-CD2 3.34Å
41E97.7Very high94.2Very high78 Ų7872.4 Ų72.436%0.36434%0.343SS..Hα-helixtrans-60.6-46170.4-66.9-174.8163.800111.3L36 R37 L43 A44 L45 L68L36-E41 HydrophobicContact CB-CG 3.92Å; R37-E41 PolarHBondContact O-N 2.99Å; E41-L43 VanDerWaalsContact C-N 3.26Å; E41-L43 PolarHBondContact O-N 3.4Å; E41-A44 WeakPolarHBondContact O-CB 3.38Å; E41-A44 PolarHBondContact O-N 3.02Å; E41-L45 WeakPolarHBondContact O-CG 3.02Å; E41-L45 PolarHBondContact O-N 2.89Å; E41-L68 HydrophobicContact CB-CD2 4.26Å; E41-L68 HydrophobicContact CG-CD2 4.31Å
42R98.3Very high94.8Very high184 Ų18468.7 Ų68.769%0.69432%0.319SS*.Hα-helixtrans-60.2-39.2174.2-72.5174.6178.2-172.70.3111.5A38 E39 R46A38-R42 WeakPolarHBondContact O-CG 3.31Å; A38-R42 PolarHBondContact O-N 3.33Å; E39-R42 PolarHBondContact O-N 3.24Å; R42-R46 WeakPolarHBondContact O-CB 2.96Å; R42-R46 PolarHBondContact O-N 3.17Å
43L98.7Very high95.6Very high63 Ų6369.7 Ų69.733%0.3333%0.33SS..Hα-helixtrans-66.9-42.3176.1-178.260.4000111.8E39 E40 E41 L45 R46 N47 L197E39-L43 WeakPolarHBondContact O-CB 3.3Å; E39-L43 PolarHBondContact O-N 3.2Å; E40-L43 CarbonylContact O-C 3.56Å; E40-L43 WeakPolarHBondContact O-CB 3.41Å; E40-L43 PolarHBondContact O-N 3.47Å; E41-L43 VanDerWaalsContact C-N 3.26Å; E41-L43 PolarHBondContact O-N 3.4Å; L43-L45 VanDerWaalsContact C-N 3.32Å; L43-L45 PolarHBondContact O-N 2.8Å; L43-R46 PolarHBondContact O-N 3.49Å; L43-N47 WeakPolarHBondContact O-CB 3.36Å; L43-N47 PolarHBondContact O-N 2.98Å; L43-N47 PolarHBondContact O-OD1 2.93Å; L43-L197 HydrophobicContact CB-CD2 4.09Å; L43-L197 HydrophobicContact CD2-CD2 4.08Å; L43-L197 HydrophobicContact CG-CD2 4.09Å
44A98.6Very high96.5Very high1 Ų170.7 Ų70.71%0.00834%0.338CS..Hα-helixtrans-57.8-45.6175.300000111.1L36 E40 E41 N47 A48 L68 I74 L197L36-A44 HydrophobicContact CD1-CB 4.34Å; E40-A44 WeakPolarHBondContact O-CB 3.38Å; E40-A44 PolarHBondContact O-N 2.75Å; E41-A44 WeakPolarHBondContact O-CB 3.38Å; E41-A44 PolarHBondContact O-N 3.02Å; A44-N47 WeakPolarHBondContact O-CB 3.43Å; A44-N47 PolarHBondContact O-N 3.28Å; A44-A48 WeakPolarHBondContact O-CB 3.45Å; A44-A48 PolarHBondContact O-N 3.18Å; A44-L68 HydrophobicContact CB-CD2 4.03Å; A44-I74 HydrophobicContact CB-CD1 4.27Å; A44-L197 HydrophobicContact CB-CD2 4.1Å
45L98.6Very high97.3Very high37 Ų3774.2 Ų74.219%0.19436%0.363CS..Hα-helixtrans-63.3-47.4176.1-65.3176.1000112E41 L43 N47 A48 L49 F64 A65 I74E41-L45 WeakPolarHBondContact O-CG 3.02Å; E41-L45 PolarHBondContact O-N 2.89Å; L43-L45 VanDerWaalsContact C-N 3.32Å; L43-L45 PolarHBondContact O-N 2.8Å; L45-N47 PolarHBondContact O-N 3.32Å; L45-A48 PolarHBondContact O-N 2.66Å; L45-L49 WeakPolarHBondContact O-CB 3.27Å; L45-L49 VanDerWaalsContact O-CG 3.24Å; L45-L49 WeakPolarHBondContact O-CG 3.31Å; L45-L49 PolarHBondContact O-N 3.18Å; L45-F64 HydrophobicContact CD2-CB 3.78Å; L45-A65 HydrophobicContact CD1-CB 3.99Å; L45-A65 HydrophobicContact CD2-CB 3.92Å; L45-A65 VanDerWaalsContact CD2-N 3.33Å; L45-I74 HydrophobicContact CD2-CD1 4.09Å
46R98.8Very high97.8Very high166 Ų16668.8 Ų68.863%0.62633%0.333SS*.Hα-helixtrans-56.8-43.1174.5-173.9-174.9-62.2155.11.2110.5R42 L43 L49 R50R42-R46 WeakPolarHBondContact O-CB 2.96Å; R42-R46 PolarHBondContact O-N 3.17Å; L43-R46 PolarHBondContact O-N 3.49Å; R46-L49 PolarHBondContact O-N 2.94Å; R46-R50 WeakPolarHBondContact O-CG 3.48Å; R46-R50 PolarHBondContact O-N 2.62Å
47N98.8Very high98.1Very high13 Ų1370.4 Ų70.47%0.0734%0.34CS..Hα-helixtrans-63.8-43.1-178.2-79.9-6.3000112.3L43 A44 L45 R50 L197L43-N47 WeakPolarHBondContact O-CB 3.36Å; L43-N47 PolarHBondContact O-N 2.98Å; L43-N47 PolarHBondContact O-OD1 2.93Å; A44-N47 WeakPolarHBondContact O-CB 3.43Å; A44-N47 PolarHBondContact O-N 3.28Å; L45-N47 PolarHBondContact O-N 3.32Å; N47-R50 VanDerWaalsContact CA-NE 3.35Å; N47-R50 PolarHBondContact O-NE 2.78Å; N47-R50 PolarHBondContact O-NH2 3.07Å; N47-R50 VanDerWaalsContact OD1-CZ 3.24Å; N47-R50 PolarHBondContact OD1-NH2 3.45Å; N47-L197 VanDerWaalsContact CB-O 3.25Å; N47-L197 WeakPolarHBondContact CB-O 3.44Å; N47-L197 PolarHBondContact ND2-O 3.23Å
48A98.8Very high98.1Very high7 Ų766.8 Ų66.86%0.05834%0.344CS..Hα-helixtrans-67.8-37.4175.800000112.7A44 L45 R50 Y51 F52 F64 I74 M76A44-A48 WeakPolarHBondContact O-CB 3.45Å; A44-A48 PolarHBondContact O-N 3.18Å; L45-A48 PolarHBondContact O-N 2.66Å; A48-R50 VanDerWaalsContact C-N 3.26Å; A48-R50 PolarHBondContact O-N 3.32Å; A48-Y51 WeakPolarHBondContact O-CD2 3.48Å; A48-F52 WeakPolarHBondContact O-CE2 3.47Å; A48-F64 HydrophobicContact CB-CD2 3.73Å; A48-F64 HydrophobicContact CB-CE2 4.13Å; A48-F64 HydrophobicContact CB-CG 4.43Å; A48-I74 HydrophobicContact CB-CD1 3.77Å; A48-I74 HydrophobicContact CB-CG2 4.03Å; A48-M76 HydrophobicContact CB-CE 3.76Å
49L98.8Very high98.2Very high21 Ų2167.2 Ų67.211%0.1134%0.339CS..Hα-helixtrans-71.1-17.4-179.2-71.7170.6000114L45 R46 Y51 F52 H57 L60 A61 F64L45-L49 WeakPolarHBondContact O-CB 3.27Å; L45-L49 VanDerWaalsContact O-CG 3.24Å; L45-L49 WeakPolarHBondContact O-CG 3.31Å; L45-L49 PolarHBondContact O-N 3.18Å; R46-L49 PolarHBondContact O-N 2.94Å; L49-Y51 PolarHBondContact O-N 3.02Å; L49-Y51 VanDerWaalsContact O-N 3.11Å; L49-F52 PolarHBondContact O-N 3.27Å; L49-H57 HydrophobicContact CD1-CB 4.48Å; L49-H57 HydrophobicContact CD2-CB 4.26Å; L49-H57 PolarHBondContact O-NE2 2.9Å; L49-L60 HydrophobicContact CD2-CB 3.89Å; L49-A61 HydrophobicContact CD1-CB 3.96Å; L49-A61 HydrophobicContact CD2-CB 4.46Å; L49-F64 HydrophobicContact CD2-CD2 4.08Å; L49-F64 HydrophobicContact CD2-CE2 4.05Å; L49-F64 HydrophobicContact CG-CD2 4.42Å
50R98.6Very high98.2Very high154 Ų15460.3 Ų60.358%0.58131%0.307SS*.THydrogen-bonded Turntrans-58.2-23.9178-72.5177-62.6-174-3114.1R46 N47 A48 F52R46-R50 WeakPolarHBondContact O-CG 3.48Å; R46-R50 PolarHBondContact O-N 2.62Å; N47-R50 VanDerWaalsContact CA-NE 3.35Å; N47-R50 PolarHBondContact O-NE 2.78Å; N47-R50 PolarHBondContact O-NH2 3.07Å; N47-R50 VanDerWaalsContact OD1-CZ 3.24Å; N47-R50 PolarHBondContact OD1-NH2 3.45Å; A48-R50 VanDerWaalsContact C-N 3.26Å; A48-R50 PolarHBondContact O-N 3.32Å; R50-F52 PolarHBondContact O-N 2.76Å
51Y98.5Very high98.2Very high30 Ų3060.5 Ų60.512%0.11831%0.312CS..THydrogen-bonded Turntrans-75.8-10.9178-64.8-80.1000113.3L11 A48 L49 M76 A136 Q137 L140 H160L11-Y51 WeakPolarHBondContact CD1-O 3.42Å; A48-Y51 WeakPolarHBondContact O-CD2 3.48Å; L49-Y51 PolarHBondContact O-N 3.02Å; L49-Y51 VanDerWaalsContact O-N 3.11Å; Y51-M76 HydrophobicContact CD2-CE 3.89Å; Y51-M76 HydrophobicContact CE2-CE 4.2Å; Y51-A136 HydrophobicContact CD1-CB 4.33Å; Y51-A136 HydrophobicContact CD2-CB 4.49Å; Y51-A136 HydrophobicContact CG-CB 4.08Å; Y51-Q137 HydrophobicContact CE1-CG 4.07Å; Y51-Q137 PolarHBondContact OH-NE2 3.25Å; Y51-L140 HydrophobicContact CD1-CD1 3.66Å; Y51-L140 HydrophobicContact CE1-CD1 4.13Å; Y51-H160 AromaticContact CE1-CE1 3.9Å; Y51-H160 AromaticContact CE1-ND1 3.41Å; Y51-H160 WeakPolarHBondContact CE1-ND1 3.48Å; Y51-H160 AromaticContact CZ-ND1 3.57Å; Y51-H160 PolarHBondContact OH-ND1 3.34Å
52F98.5Very high98.2Very high10 Ų1061 Ų614%0.04432%0.324CS..SBendtrans-124.6145.6-167.3-54.5-76.6000111.9L11 L13 A48 L49 R50 H57 L60 F64 M76 F79 A136L11-F52 HydrophobicContact CD1-CD1 4.28Å; L11-F52 HydrophobicContact CD1-CE1 4.03Å; L11-F52 HydrophobicContact CD2-CE1 4.16Å; L13-F52 HydrophobicContact CD2-CD1 3.76Å; L13-F52 HydrophobicContact CD2-CE1 4.36Å; A48-F52 WeakPolarHBondContact O-CE2 3.47Å; L49-F52 PolarHBondContact O-N 3.27Å; R50-F52 PolarHBondContact O-N 2.76Å; F52-H57 PolarHBondContact O-NE2 3.27Å; F52-L60 HydrophobicContact CB-CD1 3.83Å; F52-L60 HydrophobicContact CD1-CD1 3.59Å; F52-L60 HydrophobicContact CD2-CD1 3.74Å; F52-L60 HydrophobicContact CE1-CD1 4.08Å; F52-L60 HydrophobicContact CE2-CD1 4.19Å; F52-L60 HydrophobicContact CG-CD1 3.4Å; F52-L60 VanDerWaalsContact CG-CD1 3.4Å; F52-L60 HydrophobicContact CZ-CD1 4.34Å; F52-F64 AromaticContact CD2-CE2 3.92Å; F52-F64 HydrophobicContact CD2-CE2 3.92Å; F52-F64 HydrophobicContact CD2-CZ 4.12Å; F52-F64 AromaticContact CE2-CE2 3.55Å; F52-F64 HydrophobicContact CE2-CE2 3.55Å; F52-F64 AromaticContact CE2-CZ 3.42Å; F52-F64 HydrophobicContact CE2-CZ 3.42Å; F52-F64 VanDerWaalsContact CE2-CZ 3.42Å; F52-F64 HydrophobicContact CZ-CE2 4.47Å; F52-F64 AromaticContact CZ-CZ 3.9Å; F52-F64 HydrophobicContact CZ-CZ 3.9Å; F52-M76 HydrophobicContact CE2-CE 4.31Å; F52-M76 HydrophobicContact CE2-SD 3.88Å; F52-M76 HydrophobicContact CZ-SD 3.87Å; F52-F79 HydrophobicContact CD1-CE2 4.41Å; F52-F79 AromaticContact CD1-CZ 3.93Å; F52-F79 HydrophobicContact CD1-CZ 3.93Å; F52-F79 HydrophobicContact CE1-CD1 4.39Å; F52-F79 HydrophobicContact CE1-CD2 4.11Å; F52-F79 AromaticContact CE1-CE1 3.71Å; F52-F79 HydrophobicContact CE1-CE1 3.71Å; F52-F79 AromaticContact CE1-CE2 3.38Å; F52-F79 HydrophobicContact CE1-CE2 3.38Å; F52-F79 AromaticContact CE1-CZ 3.14Å; F52-F79 HydrophobicContact CE1-CZ 3.14Å; F52-F79 HydrophobicContact CE2-CE2 4.47Å; F52-F79 AromaticContact CZ-CD2 3.94Å; F52-F79 HydrophobicContact CZ-CD2 3.94Å; F52-F79 HydrophobicContact CZ-CE1 4.48Å; F52-F79 AromaticContact CZ-CE2 3.4Å; F52-F79 HydrophobicContact CZ-CE2 3.4Å; F52-F79 AromaticContact CZ-CZ 3.72Å; F52-F79 HydrophobicContact CZ-CZ 3.72Å; F52-A136 HydrophobicContact CZ-CB 3.93Å
53P97.7Very high98.2Very high50 Ų5052.9 Ų52.933%0.32530%0.295SS..  trans-59.4150.5170-25.233.6000112.9L13 S55 H56 H57L13-P53 HydrophobicContact CD1-CG 3.73Å; P53-S55 PolarHBondContact O-N 3.47Å; P53-S55 VanDerWaalsContact O-N 3.08Å; P53-H56 PolarHBondContact O-N 2.75Å; P53-H56 VanDerWaalsContact O-N 3.08Å; P53-H57 PolarHBondContact O-CD2 3.14Å; P53-H57 PolarHBondContact O-NE2 2.93Å
54P98.1Very high98.2Very high106 Ų10649.9 Ų49.969%0.68828%0.279SS*.G310 helixtrans-54.2-29.6179.6-28.736.1000115.1H56 H57P54-H56 PolarHBondContact O-N 3.3Å; P54-H57 WeakPolarHBondContact O-CB 3.27Å; P54-H57 PolarHBondContact O-N 3.45Å; P54-H57 VanDerWaalsContact O-N 3.12Å
55S97.4Very high98.2Very high91 Ų9150.6 Ų50.664%0.63628%0.284SS*.G310 helixtrans-57.3-29177.950.30000113.7P53P53-S55 PolarHBondContact O-N 3.47Å; P53-S55 VanDerWaalsContact O-N 3.08Å
56H97.9Very high98.1Very high15 Ų1553.7 Ų53.77%0.06930%0.298CS..G310 helixtrans-97.7-6.3-179.2-55.3-66.4000113.4L13 D14 L16 P53 P54 A58 T59 L60L13-H56 PolarHBondContact O-CE1 3.34Å; D14-H56 IonicContact OD1-CE1 2.73Å; D14-H56 PolarHBondContact OD1-CE1 2.94Å; D14-H56 IonicContact OD1-NE2 2.8Å; L16-H56 HydrophobicContact CD1-CB 4.27Å; P53-H56 PolarHBondContact O-N 2.75Å; P53-H56 VanDerWaalsContact O-N 3.08Å; P54-H56 PolarHBondContact O-N 3.3Å; H56-A58 VanDerWaalsContact C-N 3.34Å; H56-A58 PolarHBondContact O-N 3.28Å; H56-T59 PolarHBondContact O-N 3.14Å; H56-L60 HydrophobicContact CB-CD1 3.82Å; H56-L60 HydrophobicContact CB-CG 4.25Å; H56-L60 WeakPolarHBondContact O-CB 3.43Å; H56-L60 WeakPolarHBondContact O-CG 3.45Å; H56-L60 PolarHBondContact O-N 3.27Å
57H98.4Very high98.1Very high57 Ų5746.1 Ų46.126%0.26427%0.27SS..Hα-helixtrans-62.4-39.3-172.1-73.5-170.7000112.6L49 F52 P53 P54 T59 L60 A61L49-H57 HydrophobicContact CD1-CB 4.48Å; L49-H57 HydrophobicContact CD2-CB 4.26Å; L49-H57 PolarHBondContact O-NE2 2.9Å; F52-H57 PolarHBondContact O-NE2 3.27Å; P53-H57 PolarHBondContact O-CD2 3.14Å; P53-H57 PolarHBondContact O-NE2 2.93Å; P54-H57 WeakPolarHBondContact O-CB 3.27Å; P54-H57 PolarHBondContact O-N 3.45Å; P54-H57 VanDerWaalsContact O-N 3.12Å; H57-T59 VanDerWaalsContact C-N 3.31Å; H57-T59 PolarHBondContact O-N 2.81Å; H57-L60 PolarHBondContact O-N 2.87Å; H57-A61 WeakPolarHBondContact O-CB 3.38Å; H57-A61 PolarHBondContact O-N 3.39Å
58A97.1Very high98Very high81 Ų8146.2 Ų46.267%0.66927%0.27SS*.Hα-helixtrans-59.5-42.2179.700000112.3H56H56-A58 VanDerWaalsContact C-N 3.34Å; H56-A58 PolarHBondContact O-N 3.28Å
59T96.6Very high97.7Very high77 Ų7754.9 Ų54.947%0.47230%0.302SS..Hα-helixtrans-73.7-49.9177.9-54.10000111.6L16 H56 H57 E63L16-T59 HydrophobicContact CD1-CG2 4.45Å; H56-T59 PolarHBondContact O-N 3.14Å; H57-T59 VanDerWaalsContact C-N 3.31Å; H57-T59 PolarHBondContact O-N 2.81Å; T59-E63 PolarHBondContact O-N 2.93Å
60L98.3Very high97.5Very high0 Ų058.1 Ų58.10%032%0.316CS..Hα-helixtrans-72.7-30.5-172.9-65.3177.6000112.8L16 L49 F52 H56 H57 S62 E63 F64 F79L16-L60 HydrophobicContact CD1-CD2 4.41Å; L49-L60 HydrophobicContact CD2-CB 3.89Å; F52-L60 HydrophobicContact CB-CD1 3.83Å; F52-L60 HydrophobicContact CD1-CD1 3.59Å; F52-L60 HydrophobicContact CD2-CD1 3.74Å; F52-L60 HydrophobicContact CE1-CD1 4.08Å; F52-L60 HydrophobicContact CE2-CD1 4.19Å; F52-L60 HydrophobicContact CG-CD1 3.4Å; F52-L60 VanDerWaalsContact CG-CD1 3.4Å; F52-L60 HydrophobicContact CZ-CD1 4.34Å; H56-L60 HydrophobicContact CB-CD1 3.82Å; H56-L60 HydrophobicContact CB-CG 4.25Å; H56-L60 WeakPolarHBondContact O-CB 3.43Å; H56-L60 WeakPolarHBondContact O-CG 3.45Å; H56-L60 PolarHBondContact O-N 3.27Å; H57-L60 PolarHBondContact O-N 2.87Å; L60-S62 PolarHBondContact O-N 3.22Å; L60-E63 PolarHBondContact O-N 2.86Å; L60-F64 HydrophobicContact CB-CD2 4.27Å; L60-F64 HydrophobicContact CB-CE1 4.47Å; L60-F64 HydrophobicContact CB-CE2 3.82Å; L60-F64 HydrophobicContact CB-CZ 3.92Å; L60-F64 HydrophobicContact CD1-CE2 4.5Å; L60-F64 HydrophobicContact CD1-CZ 4.25Å; L60-F64 HydrophobicContact CD2-CE1 4.33Å; L60-F64 HydrophobicContact CD2-CZ 4.13Å; L60-F64 HydrophobicContact CG-CZ 4.32Å; L60-F64 WeakPolarHBondContact O-CB 3.34Å; L60-F64 WeakPolarHBondContact O-CD2 3.48Å; L60-F64 WeakPolarHBondContact O-CG 3.38Å; L60-F64 PolarHBondContact O-N 3.4Å; L60-F79 HydrophobicContact CD1-CZ 4.34Å; L60-F79 HydrophobicContact CD2-CE2 4.15Å; L60-F79 HydrophobicContact CD2-CZ 4.26Å
61A98.4Very high97.2Very high29 Ų2952.7 Ų52.724%0.2430%0.296CS..Hα-helixtrans-61.1-44.5178.600000111.9L49 H57 A65L49-A61 HydrophobicContact CD1-CB 3.96Å; L49-A61 HydrophobicContact CD2-CB 4.46Å; H57-A61 WeakPolarHBondContact O-CB 3.38Å; H57-A61 PolarHBondContact O-N 3.39Å; A61-A65 VanDerWaalsContact O-CB 3.28Å; A61-A65 WeakPolarHBondContact O-CB 3.4Å; A61-A65 PolarHBondContact O-N 3.32Å
62S97.5Very high97Very high88 Ų8851.4 Ų51.462%0.61529%0.292SS*.Hα-helixtrans-65.4-41.6177.3-630000111.9L60 A65 Q66L60-S62 PolarHBondContact O-N 3.22Å; S62-A65 PolarHBondContact O-N 3.03Å; S62-Q66 PolarHBondContact O-N 3.01Å
63E98Very high96.9Very high15 Ų1551 Ų517%0.0729%0.29CS..Hα-helixtrans-64.2-47.9177.1-177.3170.7119.800111.7N19 T59 L60 A65 Q66 E67 R78N19-E63 PolarHBondContact ND2-OE1 3.5Å; N19-E63 PolarHBondContact ND2-OE2 2.97Å; T59-E63 PolarHBondContact O-N 2.93Å; L60-E63 PolarHBondContact O-N 2.86Å; E63-A65 VanDerWaalsContact C-N 3.33Å; E63-A65 PolarHBondContact O-N 3.23Å; E63-Q66 WeakPolarHBondContact O-CB 3.35Å; E63-Q66 PolarHBondContact O-N 3.28Å; E63-Q66 VanDerWaalsContact O-N 3.09Å; E63-E67 PolarHBondContact O-N 3.34Å; E63-R78 WeakPolarHBondContact OE1-CB 3.24Å; E63-R78 IonicContact OE1-NE 3.97Å; E63-R78 PolarHBondContact OE1-NE 2.86Å; E63-R78 IonicContact OE2-CZ 3.64Å; E63-R78 VanDerWaalsContact OE2-CZ 3.3Å; E63-R78 IonicContact OE2-NE 3.87Å; E63-R78 PolarHBondContact OE2-NE 2.82Å; E63-R78 IonicContact OE2-NH2 2.71Å; E63-R78 PolarHBondContact OE2-NH2 3.02Å
64F98.5Very high97Very high0 Ų049 Ų490%028%0.277CS..Hα-helixtrans-66.5-34.7178.6-63.1-15.5000112.2L45 A48 L49 F52 L60 Q66 E67 L68 I74 M76 F79L45-F64 HydrophobicContact CD2-CB 3.78Å; A48-F64 HydrophobicContact CB-CD2 3.73Å; A48-F64 HydrophobicContact CB-CE2 4.13Å; A48-F64 HydrophobicContact CB-CG 4.43Å; L49-F64 HydrophobicContact CD2-CD2 4.08Å; L49-F64 HydrophobicContact CD2-CE2 4.05Å; L49-F64 HydrophobicContact CG-CD2 4.42Å; F52-F64 AromaticContact CD2-CE2 3.92Å; F52-F64 HydrophobicContact CD2-CE2 3.92Å; F52-F64 HydrophobicContact CD2-CZ 4.12Å; F52-F64 AromaticContact CE2-CE2 3.55Å; F52-F64 HydrophobicContact CE2-CE2 3.55Å; F52-F64 AromaticContact CE2-CZ 3.42Å; F52-F64 HydrophobicContact CE2-CZ 3.42Å; F52-F64 VanDerWaalsContact CE2-CZ 3.42Å; F52-F64 HydrophobicContact CZ-CE2 4.47Å; F52-F64 AromaticContact CZ-CZ 3.9Å; F52-F64 HydrophobicContact CZ-CZ 3.9Å; L60-F64 HydrophobicContact CB-CD2 4.27Å; L60-F64 HydrophobicContact CB-CE1 4.47Å; L60-F64 HydrophobicContact CB-CE2 3.82Å; L60-F64 HydrophobicContact CB-CZ 3.92Å; L60-F64 HydrophobicContact CD1-CE2 4.5Å; L60-F64 HydrophobicContact CD1-CZ 4.25Å; L60-F64 HydrophobicContact CD2-CE1 4.33Å; L60-F64 HydrophobicContact CD2-CZ 4.13Å; L60-F64 HydrophobicContact CG-CZ 4.32Å; L60-F64 WeakPolarHBondContact O-CB 3.34Å; L60-F64 WeakPolarHBondContact O-CD2 3.48Å; L60-F64 WeakPolarHBondContact O-CG 3.38Å; L60-F64 PolarHBondContact O-N 3.4Å; F64-Q66 VanDerWaalsContact C-N 3.28Å; F64-Q66 PolarHBondContact O-N 3.03Å; F64-E67 PolarHBondContact O-N 3.32Å; F64-L68 WeakPolarHBondContact O-CB 3.09Å; F64-L68 PolarHBondContact O-N 2.97Å; F64-I74 HydrophobicContact CB-CD1 4.14Å; F64-I74 HydrophobicContact CB-CG1 4.29Å; F64-I74 HydrophobicContact CB-CG2 3.68Å; F64-I74 HydrophobicContact CD1-CG2 3.61Å; F64-I74 HydrophobicContact CD2-CG2 4.2Å; F64-I74 HydrophobicContact CE1-CG2 4.3Å; F64-I74 HydrophobicContact CG-CG2 3.56Å; F64-M76 HydrophobicContact CD1-CG 4.33Å; F64-M76 HydrophobicContact CE1-CB 3.95Å; F64-M76 HydrophobicContact CE1-CG 3.7Å; F64-M76 HydrophobicContact CZ-CB 4.34Å; F64-M76 HydrophobicContact CZ-CG 3.86Å; F64-M76 HydrophobicContact CZ-SD 4.2Å; F64-F79 HydrophobicContact CZ-CE2 4.48Å
65A98.2Very high97Very high15 Ų1544 Ų4412%0.12424%0.244CC..Hα-helixtrans-65-34.9172.500000111.9L45 A61 S62 E63 R69L45-A65 HydrophobicContact CD1-CB 3.99Å; L45-A65 HydrophobicContact CD2-CB 3.92Å; L45-A65 VanDerWaalsContact CD2-N 3.33Å; A61-A65 VanDerWaalsContact O-CB 3.28Å; A61-A65 WeakPolarHBondContact O-CB 3.4Å; A61-A65 PolarHBondContact O-N 3.32Å; S62-A65 PolarHBondContact O-N 3.03Å; E63-A65 VanDerWaalsContact C-N 3.33Å; E63-A65 PolarHBondContact O-N 3.23Å; A65-R69 VanDerWaalsContact O-CG 3.29Å; A65-R69 WeakPolarHBondContact O-CG 3.39Å; A65-R69 PolarHBondContact O-N 3.44Å
66Q97.4Very high97Very high102 Ų10239.7 Ų39.748%0.47721%0.214SC..Hα-helixtrans-68.3-46.9174.3-176.217610.300111.4S62 E63 F64 L68 R69 Q70S62-Q66 PolarHBondContact O-N 3.01Å; E63-Q66 WeakPolarHBondContact O-CB 3.35Å; E63-Q66 PolarHBondContact O-N 3.28Å; E63-Q66 VanDerWaalsContact O-N 3.09Å; F64-Q66 VanDerWaalsContact C-N 3.28Å; F64-Q66 PolarHBondContact O-N 3.03Å; Q66-L68 VanDerWaalsContact C-N 3.34Å; Q66-L68 PolarHBondContact O-N 2.97Å; Q66-R69 PolarHBondContact O-N 3.26Å; Q66-Q70 HydrophobicContact CG-CG 4.23Å; Q66-Q70 VanDerWaalsContact NE2-NE2 3.16Å; Q66-Q70 WeakPolarHBondContact O-CB 3.47Å; Q66-Q70 VanDerWaalsContact O-CG 3.32Å; Q66-Q70 WeakPolarHBondContact O-CG 3.26Å; Q66-Q70 PolarHBondContact O-N 3.12Å
67E97.7Very high97Very high8 Ų839.3 Ų39.34%0.03721%0.212CC..Hα-helixtrans-58.6-45.8176-70.6-169.2-17500111.7E63 F64 R69 Q70 Y71 H73 Y75 M76 Y77E63-E67 PolarHBondContact O-N 3.34Å; F64-E67 PolarHBondContact O-N 3.32Å; E67-R69 VanDerWaalsContact C-N 3.31Å; E67-R69 PolarHBondContact O-N 3.07Å; E67-Q70 PolarHBondContact O-N 3.24Å; E67-Y71 HydrophobicContact CB-CD2 3.98Å; E67-Y71 HydrophobicContact CB-CE2 4.36Å; E67-Y71 HydrophobicContact CG-CD2 4.22Å; E67-Y71 HydrophobicContact CG-CE2 4.14Å; E67-Y71 WeakPolarHBondContact O-CB 3.33Å; E67-Y71 WeakPolarHBondContact O-CD2 3.37Å; E67-Y71 PolarHBondContact O-N 3.43Å; E67-H73 CarbonylContact C-O 3.51Å; E67-Y75 PolarHBondContact OE2-N 2.94Å; E67-M76 PolarHBondContact OE1-N 3.42Å; E67-M76 PolarHBondContact OE2-N 3.44Å; E67-Y77 HydrophobicContact CG-CD2 4.25Å; E67-Y77 VanDerWaalsContact OE1-CD2 3.31Å; E67-Y77 WeakPolarHBondContact OE1-CD2 3.49Å; E67-Y77 PolarHBondContact OE1-N 2.7Å
68L96.7Very high97Very high15 Ų1538.3 Ų38.38%0.07921%0.206CC..Hα-helixtrans-58.5-42.8178.9-174.562.8000111.8L36 E41 A44 F64 Q66 G72 I74 A196L36-L68 HydrophobicContact CD1-CD1 4.3Å; L36-L68 HydrophobicContact CD1-CD2 4.43Å; E41-L68 HydrophobicContact CB-CD2 4.26Å; E41-L68 HydrophobicContact CG-CD2 4.31Å; A44-L68 HydrophobicContact CB-CD2 4.03Å; F64-L68 WeakPolarHBondContact O-CB 3.09Å; F64-L68 PolarHBondContact O-N 2.97Å; Q66-L68 VanDerWaalsContact C-N 3.34Å; Q66-L68 PolarHBondContact O-N 2.97Å; L68-G72 WeakPolarHBondContact O-CA 3.42Å; L68-G72 PolarHBondContact O-N 2.87Å; L68-I74 HydrophobicContact CB-CD1 4.47Å; L68-I74 HydrophobicContact CB-CG1 3.98Å; L68-I74 HydrophobicContact CD1-CG1 4.37Å; L68-A196 HydrophobicContact CD1-CB 4.48Å
69R94.2Very high97Very high189 Ų18934.4 Ų34.471%0.71317%0.174SC*.Hα-helixtrans-71.3-38.7178.3-71.5172.7-170.6147.82.9113.2A65 Q66 E67A65-R69 VanDerWaalsContact O-CG 3.29Å; A65-R69 WeakPolarHBondContact O-CG 3.39Å; A65-R69 PolarHBondContact O-N 3.44Å; Q66-R69 PolarHBondContact O-N 3.26Å; E67-R69 VanDerWaalsContact C-N 3.31Å; E67-R69 PolarHBondContact O-N 3.07Å
70Q93.5Very high97Very high88 Ų8832.3 Ų32.341%0.41116%0.162SC..Hα-helixtrans-80.9-33.1-174.7-71.8-175.6-14.400112.6V31 Q66 E67V31-Q70 WeakPolarHBondContact CG1-O 3.32Å; Q66-Q70 HydrophobicContact CG-CG 4.23Å; Q66-Q70 VanDerWaalsContact NE2-NE2 3.16Å; Q66-Q70 WeakPolarHBondContact O-CB 3.47Å; Q66-Q70 VanDerWaalsContact O-CG 3.32Å; Q66-Q70 WeakPolarHBondContact O-CG 3.26Å; Q66-Q70 PolarHBondContact O-N 3.12Å; E67-Q70 PolarHBondContact O-N 3.24Å
71Y93.6Very high96.8Very high40 Ų4032.9 Ų32.916%0.15717%0.166CC..Hα-helixtrans-123-9.5-168.2-47.5-49.2000113.4R22 R32 E67 H73 Y77R22-Y71 VanDerWaalsContact CZ-CE1 3.44Å; R32-Y71 PolarHBondContact N-O 3.37Å; E67-Y71 HydrophobicContact CB-CD2 3.98Å; E67-Y71 HydrophobicContact CB-CE2 4.36Å; E67-Y71 HydrophobicContact CG-CD2 4.22Å; E67-Y71 HydrophobicContact CG-CE2 4.14Å; E67-Y71 WeakPolarHBondContact O-CB 3.33Å; E67-Y71 WeakPolarHBondContact O-CD2 3.37Å; E67-Y71 PolarHBondContact O-N 3.43Å; Y71-H73 PolarHBondContact O-N 2.87Å; Y71-Y77 AromaticContact CD2-CE2 3.69Å; Y71-Y77 HydrophobicContact CD2-CE2 3.69Å; Y71-Y77 HydrophobicContact CE2-CD2 4.16Å; Y71-Y77 AromaticContact CE2-CE2 3.53Å; Y71-Y77 HydrophobicContact CE2-CE2 3.53Å
72G92.9Very high96.5Very high4 Ų434.1 Ų34.14%0.04118%0.176CC..SBendtrans74.28.4-174.800000114R32 L68R32-G72 VanDerWaalsContact O-CA 3.24Å; R32-G72 WeakPolarHBondContact O-CA 3.48Å; L68-G72 WeakPolarHBondContact O-CA 3.42Å; L68-G72 PolarHBondContact O-N 2.87Å
73H97.3Very high96.3Very high2 Ų230.4 Ų30.41%0.00915%0.149CC..SBendtrans-159157.3-178.7-170.762.7000111.6E67 Y71 Y75 S133 F195E67-H73 CarbonylContact C-O 3.51Å; Y71-H73 PolarHBondContact O-N 2.87Å; H73-Y75 HydrophobicContact CB-CD2 4.33Å; H73-Y75 HydrophobicContact CB-CE2 3.75Å; H73-Y75 AromaticContact CD2-CD1 3.6Å; H73-Y75 AromaticContact CD2-CE1 3.5Å; H73-Y75 VanDerWaalsContact CD2-CE1 3.5Å; H73-Y75 WeakPolarHBondContact CD2-CE1 3.22Å; H73-Y75 AromaticContact CD2-CE2 3.96Å; H73-Y75 AromaticContact CD2-CG 3.88Å; H73-Y75 AromaticContact CD2-CZ 3.69Å; H73-S133 PolarHBondContact CE1-OG 3.13Å; H73-S133 PolarHBondContact NE2-O 3.41Å; H73-S133 PolarHBondContact NE2-OG 3.26Å; H73-F195 HydrophobicContact CB-CE1 3.92Å; H73-F195 HydrophobicContact CB-CZ 4.41Å; H73-F195 AromaticContact CD2-CE1 3.88Å; H73-F195 AromaticContact CD2-CZ 3.49Å; H73-F195 VanDerWaalsContact CD2-CZ 3.49Å; H73-F195 WeakPolarHBondContact CD2-CZ 3.4Å; H73-F195 AromaticContact CE1-CE1 3.89Å; H73-F195 AromaticContact CE1-CE2 3.56Å; H73-F195 AromaticContact CE1-CZ 3.52Å; H73-F195 PolarHBondContact CE1-O 3.13Å; H73-F195 AromaticContact CG-CE1 3.47Å; H73-F195 VanDerWaalsContact CG-CE1 3.47Å; H73-F195 AromaticContact CG-CZ 3.57Å; H73-F195 AromaticContact ND1-CD1 3.83Å; H73-F195 AromaticContact ND1-CE1 3.52Å; H73-F195 AromaticContact ND1-CZ 3.64Å; H73-F195 PolarHBondContact ND1-O 2.89Å; H73-F195 AromaticContact NE2-CE2 3.67Å; H73-F195 AromaticContact NE2-CZ 3.43Å; H73-F195 WeakPolarHBondContact NE2-CZ 3.44Å
74I98.4Very high96.1Very high7 Ų738.4 Ų38.44%0.03618%0.179CC..  trans-103.895178.5-54.4165.9000108.5A44 L45 A48 F64 L68 M76 N134A44-I74 HydrophobicContact CB-CD1 4.27Å; L45-I74 HydrophobicContact CD2-CD1 4.09Å; A48-I74 HydrophobicContact CB-CD1 3.77Å; A48-I74 HydrophobicContact CB-CG2 4.03Å; F64-I74 HydrophobicContact CB-CD1 4.14Å; F64-I74 HydrophobicContact CB-CG1 4.29Å; F64-I74 HydrophobicContact CB-CG2 3.68Å; F64-I74 HydrophobicContact CD1-CG2 3.61Å; F64-I74 HydrophobicContact CD2-CG2 4.2Å; F64-I74 HydrophobicContact CE1-CG2 4.3Å; F64-I74 HydrophobicContact CG-CG2 3.56Å; L68-I74 HydrophobicContact CB-CD1 4.47Å; L68-I74 HydrophobicContact CB-CG1 3.98Å; L68-I74 HydrophobicContact CD1-CG1 4.37Å; I74-M76 HydrophobicContact CG2-CE 4.32Å; I74-M76 HydrophobicContact CG2-CG 3.85Å; I74-N134 WeakPolarHBondContact O-CB 3.49Å
75Y98.4Very high96Very high0 Ų039.3 Ų39.30%018%0.183CC..  trans-83.8-20.8179.7-65.7-78.5000112.6E67 H73 Y77 E121 L122 N134 W135 F195E67-Y75 PolarHBondContact OE2-N 2.94Å; H73-Y75 HydrophobicContact CB-CD2 4.33Å; H73-Y75 HydrophobicContact CB-CE2 3.75Å; H73-Y75 AromaticContact CD2-CD1 3.6Å; H73-Y75 AromaticContact CD2-CE1 3.5Å; H73-Y75 VanDerWaalsContact CD2-CE1 3.5Å; H73-Y75 WeakPolarHBondContact CD2-CE1 3.22Å; H73-Y75 AromaticContact CD2-CE2 3.96Å; H73-Y75 AromaticContact CD2-CG 3.88Å; H73-Y75 AromaticContact CD2-CZ 3.69Å; Y75-Y77 AromaticContact CD2-CE2 3.86Å; Y75-Y77 HydrophobicContact CD2-CE2 3.86Å; Y75-Y77 AromaticContact CD2-CZ 3.65Å; Y75-Y77 VanDerWaalsContact CD2-OH 3.25Å; Y75-Y77 WeakPolarHBondContact CD2-OH 3.31Å; Y75-Y77 HydrophobicContact CG-CE1 4.37Å; Y75-Y77 HydrophobicContact CG-CE2 4.24Å; Y75-Y77 AromaticContact CG-CZ 3.87Å; Y75-E121 HydrophobicContact CD1-CB 4Å; Y75-E121 HydrophobicContact CD1-CG 4.05Å; Y75-E121 HydrophobicContact CD2-CG 4.29Å; Y75-E121 HydrophobicContact CE1-CB 3.51Å; Y75-E121 HydrophobicContact CE1-CG 3.63Å; Y75-E121 HydrophobicContact CE2-CG 3.89Å; Y75-E121 HydrophobicContact CG-CG 4.36Å; Y75-L122 HydrophobicContact CD1-CD1 4.36Å; Y75-N134 WeakPolarHBondContact O-CA 3.37Å; Y75-N134 WeakPolarHBondContact O-CB 3.1Å; Y75-W135 PolarHBondContact O-N 3.38Å; Y75-F195 HydrophobicContact CE1-CZ 4.46Å
76M98.5Very high96Very high1 Ų142.4 Ų42.41%0.00519%0.192CC..  trans62.352.6-177.2-45.1175.4-177.900111.7A48 Y51 F52 F64 E67 I74 R78 F79 N134 A136A48-M76 HydrophobicContact CB-CE 3.76Å; Y51-M76 HydrophobicContact CD2-CE 3.89Å; Y51-M76 HydrophobicContact CE2-CE 4.2Å; F52-M76 HydrophobicContact CE2-CE 4.31Å; F52-M76 HydrophobicContact CE2-SD 3.88Å; F52-M76 HydrophobicContact CZ-SD 3.87Å; F64-M76 HydrophobicContact CD1-CG 4.33Å; F64-M76 HydrophobicContact CE1-CB 3.95Å; F64-M76 HydrophobicContact CE1-CG 3.7Å; F64-M76 HydrophobicContact CZ-CB 4.34Å; F64-M76 HydrophobicContact CZ-CG 3.86Å; F64-M76 HydrophobicContact CZ-SD 4.2Å; E67-M76 PolarHBondContact OE1-N 3.42Å; E67-M76 PolarHBondContact OE2-N 3.44Å; I74-M76 HydrophobicContact CG2-CE 4.32Å; I74-M76 HydrophobicContact CG2-CG 3.85Å; M76-R78 PolarHBondContact O-N 3.01Å; M76-F79 HydrophobicContact CB-CD2 3.94Å; M76-F79 PolarHBondContact O-N 3.08Å; M76-N134 HydrophobicContact CE-CB 4.11Å; M76-N134 HydrophobicContact CG-CB 3.98Å; M76-N134 HydrophobicContact SD-CB 3.92Å; M76-A136 HydrophobicContact SD-CB 3.39Å; M76-A136 WeakPolarHBondContact SD-CB 3.44Å
77Y98Very high96Very high7 Ų738.2 Ų38.23%0.02718%0.175CC..G310 helixtrans-55-29.5-171.6-70.2-71.1000113.6R22 E67 Y71 Y75 F79 C80 Q120 E121R22-Y77 HydrophobicContact CG-CE1 4.04Å; R22-Y77 HydrophobicContact CG-CE2 4.17Å; R22-Y77 PolarHBondContact NE-OH 2.91Å; R22-Y77 PolarHBondContact NH2-OH 2.74Å; E67-Y77 HydrophobicContact CG-CD2 4.25Å; E67-Y77 VanDerWaalsContact OE1-CD2 3.31Å; E67-Y77 WeakPolarHBondContact OE1-CD2 3.49Å; E67-Y77 PolarHBondContact OE1-N 2.7Å; Y71-Y77 AromaticContact CD2-CE2 3.69Å; Y71-Y77 HydrophobicContact CD2-CE2 3.69Å; Y71-Y77 HydrophobicContact CE2-CD2 4.16Å; Y71-Y77 AromaticContact CE2-CE2 3.53Å; Y71-Y77 HydrophobicContact CE2-CE2 3.53Å; Y75-Y77 AromaticContact CD2-CE2 3.86Å; Y75-Y77 HydrophobicContact CD2-CE2 3.86Å; Y75-Y77 AromaticContact CD2-CZ 3.65Å; Y75-Y77 VanDerWaalsContact CD2-OH 3.25Å; Y75-Y77 WeakPolarHBondContact CD2-OH 3.31Å; Y75-Y77 HydrophobicContact CG-CE1 4.37Å; Y75-Y77 HydrophobicContact CG-CE2 4.24Å; Y75-Y77 AromaticContact CG-CZ 3.87Å; Y77-F79 PolarHBondContact O-N 2.89Å; Y77-F79 VanDerWaalsContact O-N 3.07Å; Y77-C80 WeakPolarHBondContact O-CB 3.4Å; Y77-C80 PolarHBondContact O-N 2.8Å; Y77-Q120 HydrophobicContact CE1-CB 4.12Å; Y77-Q120 WeakPolarHBondContact CE1-O 3.43Å; Y77-E121 WeakPolarHBondContact CE1-OE1 3.45Å; Y77-E121 WeakPolarHBondContact OH-CG 3.4Å; Y77-E121 PolarHBondContact OH-OE1 2.82Å
78R97.2Very high96.1Very high36 Ų3639.1 Ų39.114%0.13618%0.178CC..G310 helixtrans-47.9-33.7171.9171.5177.6-62.3-101.19.5113.9P17 N19 E63 M76P17-R78 HydrophobicContact CG-CG 3.76Å; P17-R78 WeakPolarHBondContact CG-O 3.39Å; P17-R78 WeakPolarHBondContact O-CG 3.41Å; P17-R78 PolarHBondContact O-NH1 2.78Å; N19-R78 HydrophobicContact CB-CB 4.33Å; E63-R78 WeakPolarHBondContact OE1-CB 3.24Å; E63-R78 IonicContact OE1-NE 3.97Å; E63-R78 PolarHBondContact OE1-NE 2.86Å; E63-R78 IonicContact OE2-CZ 3.64Å; E63-R78 VanDerWaalsContact OE2-CZ 3.3Å; E63-R78 IonicContact OE2-NE 3.87Å; E63-R78 PolarHBondContact OE2-NE 2.82Å; E63-R78 IonicContact OE2-NH2 2.71Å; E63-R78 PolarHBondContact OE2-NH2 3.02Å; M76-R78 PolarHBondContact O-N 3.01Å
79F97.4Very high96.1Very high0 Ų040.2 Ų40.20%019%0.186CC..G310 helixtrans-95.1-1.6-174.7-61-81.2000113.9L11 P12 L16 P17 F52 L60 F64 M76 Y77 W135 R139L11-F79 HydrophobicContact CD2-CD1 4.1Å; L11-F79 HydrophobicContact CD2-CG 4.47Å; P12-F79 HydrophobicContact CG-CD1 4.23Å; L16-F79 HydrophobicContact CD2-CE1 4.29Å; L16-F79 HydrophobicContact CD2-CZ 4.02Å; P17-F79 HydrophobicContact CG-CD1 4.26Å; P17-F79 HydrophobicContact CG-CE1 4.32Å; F52-F79 HydrophobicContact CD1-CE2 4.41Å; F52-F79 AromaticContact CD1-CZ 3.93Å; F52-F79 HydrophobicContact CD1-CZ 3.93Å; F52-F79 HydrophobicContact CE1-CD1 4.39Å; F52-F79 HydrophobicContact CE1-CD2 4.11Å; F52-F79 AromaticContact CE1-CE1 3.71Å; F52-F79 HydrophobicContact CE1-CE1 3.71Å; F52-F79 AromaticContact CE1-CE2 3.38Å; F52-F79 HydrophobicContact CE1-CE2 3.38Å; F52-F79 AromaticContact CE1-CZ 3.14Å; F52-F79 HydrophobicContact CE1-CZ 3.14Å; F52-F79 HydrophobicContact CE2-CE2 4.47Å; F52-F79 AromaticContact CZ-CD2 3.94Å; F52-F79 HydrophobicContact CZ-CD2 3.94Å; F52-F79 HydrophobicContact CZ-CE1 4.48Å; F52-F79 AromaticContact CZ-CE2 3.4Å; F52-F79 HydrophobicContact CZ-CE2 3.4Å; F52-F79 AromaticContact CZ-CZ 3.72Å; F52-F79 HydrophobicContact CZ-CZ 3.72Å; L60-F79 HydrophobicContact CD1-CZ 4.34Å; L60-F79 HydrophobicContact CD2-CE2 4.15Å; L60-F79 HydrophobicContact CD2-CZ 4.26Å; F64-F79 HydrophobicContact CZ-CE2 4.48Å; M76-F79 HydrophobicContact CB-CD2 3.94Å; M76-F79 PolarHBondContact O-N 3.08Å; Y77-F79 PolarHBondContact O-N 2.89Å; Y77-F79 VanDerWaalsContact O-N 3.07Å; F79-W135 HydrophobicContact CB-CB 3.97Å; F79-R139 PolarHBondContact O-NE 2.71Å
80C96.3Very high96.3Very high32 Ų3231.4 Ų31.422%0.21615%0.153CC..SBendtrans-56.7122.8170.8-176.40000109.8Y77 W135Y77-C80 WeakPolarHBondContact O-CB 3.4Å; Y77-C80 PolarHBondContact O-N 2.8Å; C80-W135 HydrophobicContact CB-CD2 3.86Å; C80-W135 HydrophobicContact CB-CE3 4.46Å; C80-W135 HydrophobicContact CB-CG 4.03Å; C80-W135 HydrophobicContact CB-CZ2 4.29Å; C80-W135 VanDerWaalsContact SG-CZ2 3.56Å
81P94.4Very high96.5Very high13 Ų1333.1 Ų33.18%0.08417%0.165CC..  trans-71147.4-173.732.2-37.7000112.1L7 V83 M85 W135 F138 R139L7-P81 HydrophobicContact CD2-CB 3.76Å; L7-P81 HydrophobicContact CD2-CG 4.16Å; P81-V83 HydrophobicContact CB-CG1 4.01Å; P81-V83 HydrophobicContact CG-CG1 4.22Å; P81-V83 PolarHBondContact O-N 2.83Å; P81-M85 HydrophobicContact CG-CE 3.81Å; P81-W135 VanDerWaalsContact CD-CZ3 3.44Å; P81-W135 HydrophobicContact CG-CZ3 4.18Å; P81-F138 HydrophobicContact CG-CE1 3.8Å; P81-F138 HydrophobicContact CG-CZ 4.37Å; P81-R139 VanDerWaalsContact CA-NH2 3.32Å
82A91.4Very high96.7Very high55 Ų5536 Ų3646%0.45518%0.18SC..SBendtrans-75.8-13.5174.200000113
83V93.3Very high96.9Very high10 Ų1036.3 Ų36.36%0.06118%0.18CC..SBendtrans-63.7139.1176.476.40000109.2S2 L4 L7 P81 M85 M108S2-V83 WeakPolarHBondContact OG-CA 3.48Å; S2-V83 PolarHBondContact OG-N 2.68Å; S2-V83 VanDerWaalsContact OG-N 3.11Å; L4-V83 HydrophobicContact CD2-CG2 4.27Å; L7-V83 HydrophobicContact CD1-CG1 4.1Å; L7-V83 HydrophobicContact CD2-CG1 3.89Å; L7-V83 HydrophobicContact CG-CG1 4.22Å; P81-V83 HydrophobicContact CB-CG1 4.01Å; P81-V83 HydrophobicContact CG-CG1 4.22Å; P81-V83 PolarHBondContact O-N 2.83Å; V83-M85 PolarHBondContact O-N 2.88Å; V83-M108 HydrophobicContact CG1-CE 4.21Å
84R94.9Very high96.8Very high182 Ų18238.6 Ų38.669%0.68720%0.195SC*.  trans-60.3115.5174.7178.9177.6179.3-178.40.4108.4R86 Y88R84-R86 HydrophobicContact CG-CG 4.48Å; R84-R86 PolarHBondContact O-N 2.96Å; R84-Y88 WeakPolarHBondContact O-CE2 3.27Å; R84-Y88 PolarHBondContact O-OH 3.27Å
85M97Very high96.7Very high19 Ų1939.5 Ų39.59%0.09420%0.202CC..  trans-73.3111.6180-169.36171.200109.7P81 V83 M108 L111 D112 P113 W135 F138P81-M85 HydrophobicContact CG-CE 3.81Å; V83-M85 PolarHBondContact O-N 2.88Å; M85-M108 HydrophobicContact SD-CB 3.81Å; M85-M108 HydrophobicContact SD-CE 3.83Å; M85-M108 HydrophobicContact SD-CG 3.75Å; M85-L111 HydrophobicContact CE-CB 4.43Å; M85-L111 HydrophobicContact CE-CD1 4.35Å; M85-L111 VanDerWaalsContact CG-C 3.43Å; M85-L111 HydrophobicContact CG-CB 3.5Å; M85-L111 WeakPolarHBondContact CG-O 3.35Å; M85-L111 HydrophobicContact SD-CB 3.9Å; M85-D112 WeakPolarHBondContact O-CA 3.37Å; M85-P113 VanDerWaalsContact O-CD 3.27Å; M85-P113 WeakPolarHBondContact O-CD 3.28Å; M85-W135 HydrophobicContact CE-CH2 3.94Å; M85-W135 HydrophobicContact CE-CZ3 3.85Å; M85-F138 HydrophobicContact CE-CE1 4.18Å; M85-F138 HydrophobicContact CE-CE2 3.76Å; M85-F138 HydrophobicContact CE-CZ 3.5Å; M85-F138 HydrophobicContact SD-CE2 4.33Å; M85-F138 HydrophobicContact SD-CZ 4.31Å
86R97.6Very high96.7Very high80 Ų8048 Ų4830%0.30223%0.234SC..SBendtrans-168.1166.2176.562.5179.1-173.598.1-10109.9R84 Y88 M108 D112R84-R86 HydrophobicContact CG-CG 4.48Å; R84-R86 PolarHBondContact O-N 2.96Å; R86-Y88 HydrophobicContact CG-CD2 3.97Å; R86-Y88 HydrophobicContact CG-CE1 4.29Å; R86-Y88 HydrophobicContact CG-CE2 3.39Å; R86-Y88 PolarHBondContact NE-OH 3.39Å; R86-Y88 WeakPolarHBondContact O-CD2 3.4Å; R86-Y88 VanDerWaalsContact O-CE2 3.28Å; R86-Y88 WeakPolarHBondContact O-CE2 3.44Å; R86-M108 VanDerWaalsContact O-CB 3.24Å; R86-M108 WeakPolarHBondContact O-CB 3.36Å; R86-D112 WeakPolarHBondContact CA-OD2 3.3Å; R86-D112 WeakPolarHBondContact CB-OD2 3.34Å
87A98.2Very high96.7Very high15 Ų1548.4 Ų48.412%0.12424%0.236CC..  trans-66.2135.216300000110.8L105 N109A87-L105 HydrophobicContact CB-CD2 3.88Å; A87-L105 HydrophobicContact CB-CG 4.01Å; A87-N109 HydrophobicContact CB-CB 4.14Å
88Y98.1Very high96.7Very high26 Ų2654.5 Ų54.510%0.10226%0.259CS..  trans-111.9162.6169.5-66.8-100.1000109.3L4 R84 R86 Y93 L105 M108L4-Y88 HydrophobicContact CD1-CD1 4.27Å; L4-Y88 HydrophobicContact CD1-CD2 4.12Å; L4-Y88 HydrophobicContact CD1-CG 3.86Å; L4-Y88 HydrophobicContact CD2-CD2 3.82Å; L4-Y88 HydrophobicContact CD2-CE2 3.88Å; L4-Y88 HydrophobicContact CD2-CG 4.36Å; L4-Y88 HydrophobicContact CG-CD2 4.46Å; R84-Y88 WeakPolarHBondContact O-CE2 3.27Å; R84-Y88 PolarHBondContact O-OH 3.27Å; R86-Y88 HydrophobicContact CG-CD2 3.97Å; R86-Y88 HydrophobicContact CG-CE1 4.29Å; R86-Y88 HydrophobicContact CG-CE2 3.39Å; R86-Y88 PolarHBondContact NE-OH 3.39Å; R86-Y88 WeakPolarHBondContact O-CD2 3.4Å; R86-Y88 VanDerWaalsContact O-CE2 3.28Å; R86-Y88 WeakPolarHBondContact O-CE2 3.44Å; Y88-Y93 PolarHBondContact N-OH 2.89Å; Y88-Y93 VanDerWaalsContact N-OH 3.07Å; Y88-Y93 WeakPolarHBondContact O-CE2 3.38Å; Y88-L105 WeakPolarHBondContact O-CD1 3.45Å; Y88-M108 HydrophobicContact CD2-CE 4.05Å; Y88-M108 HydrophobicContact CD2-SD 4.45Å; Y88-M108 HydrophobicContact CE2-CE 3.7Å
89P98.3Very high96.7Very high39 Ų3953.5 Ų53.525%0.25326%0.256SS..  trans-54.6139.1169-24.933.7000111.3D91 Q92 T454 S455P89-D91 PolarHBondContact O-N 3.31Å; P89-D91 VanDerWaalsContact O-N 3.14Å; P89-Q92 HydrophobicContact CB-CG 4.29Å; P89-Q92 WeakPolarHBondContact O-CB 3.22Å; P89-Q92 PolarHBondContact O-N 3.17Å; P89-T454 CarbonylContact C-O 3.32Å; P89-T454 WeakPolarHBondContact CA-O 3.38Å; P89-S455 WeakPolarHBondContact CB-O 3.27Å; P89-S455 WeakPolarHBondContact CG-O 3.21Å
90I98.3Very high96.8Very high3 Ų353.5 Ų53.52%0.01526%0.256CS..G310 helixtrans-54.6-37.2-171-166.6167.1000114Q92 Y93 A101 A102 T454 A536I90-Q92 PolarHBondContact O-N 3.42Å; I90-Y93 PolarHBondContact O-N 2.92Å; I90-Y93 VanDerWaalsContact O-N 3.14Å; I90-A101 HydrophobicContact CD1-CB 4.37Å; I90-A101 HydrophobicContact CG1-CB 3.74Å; I90-A102 HydrophobicContact CD1-CB 4.02Å; I90-T454 HydrophobicContact CD1-CG2 4.24Å; I90-T454 WeakPolarHBondContact CG2-OG1 3.03Å; I90-T454 PolarHBondContact N-O 2.86Å; I90-A536 HydrophobicContact CG2-CB 4.27Å
91D97Very high96.9Very high124 Ų12452.2 Ų52.266%0.66325%0.248SC*.G310 helixtrans-71.8-8.7-177.9-61.5-41.1000113.4P89P89-D91 PolarHBondContact O-N 3.31Å; P89-D91 VanDerWaalsContact O-N 3.14Å
92Q97.1Very high97.1Very high101 Ų10151.6 Ų51.647%0.47224%0.244SC..G310 helixtrans-83.3-16173.9-58.2-17312.700112.7L4 P89 I90 P94L4-Q92 HydrophobicContact CD1-CB 3.79Å; L4-Q92 WeakPolarHBondContact CD1-O 3.21Å; P89-Q92 HydrophobicContact CB-CG 4.29Å; P89-Q92 WeakPolarHBondContact O-CB 3.22Å; P89-Q92 PolarHBondContact O-N 3.17Å; I90-Q92 PolarHBondContact O-N 3.42Å; Q92-P94 WeakPolarHBondContact O-CD 3.34Å
93Y97.6Very high97.4Very high11 Ų1149.1 Ų49.14%0.04322%0.223CC..SBendtrans-80.9120.5178-68.6-88.3000110L4 Y88 I90 C95 M104 L105 M108L4-Y93 HydrophobicContact CD1-CD1 4.37Å; L4-Y93 HydrophobicContact CD1-CE1 4.33Å; L4-Y93 HydrophobicContact CD2-CE1 4.47Å; Y88-Y93 PolarHBondContact N-OH 2.89Å; Y88-Y93 VanDerWaalsContact N-OH 3.07Å; Y88-Y93 WeakPolarHBondContact O-CE2 3.38Å; I90-Y93 PolarHBondContact O-N 2.92Å; I90-Y93 VanDerWaalsContact O-N 3.14Å; Y93-C95 PolarHBondContact O-N 3.43Å; Y93-M104 HydrophobicContact CD1-CB 3.52Å; Y93-M104 HydrophobicContact CD1-CE 4Å; Y93-M104 HydrophobicContact CD1-CG 4.46Å; Y93-M104 HydrophobicContact CD1-SD 4.24Å; Y93-M104 HydrophobicContact CE1-CB 3.7Å; Y93-M104 HydrophobicContact CG-CB 4.31Å; Y93-L105 HydrophobicContact CD2-CB 4.46Å; Y93-L105 HydrophobicContact CE2-CB 3.73Å; Y93-L105 HydrophobicContact CE2-CD1 4.44Å; Y93-L105 HydrophobicContact CE2-CG 4.22Å; Y93-L105 WeakPolarHBondContact OH-CA 3.49Å; Y93-M108 HydrophobicContact CE1-SD 3.54Å; Y93-M108 VanDerWaalsContact CE1-SD 3.54Å; Y93-M108 PolarHBondContact OH-SD 3.33Å
94P95.3Very high97.7Very high49 Ų4948.6 Ų48.632%0.31822%0.22SC..  trans-81.764-177.136-38.6000111K5 C8 Q92K5-P94 HydrophobicContact CG-CB 4.3Å; K5-P94 HydrophobicContact CG-CG 4.02Å; C8-P94 WeakPolarHBondContact SG-CG 3.45Å; Q92-P94 WeakPolarHBondContact O-CD 3.34Å
95C97.5Very high97.9Very high27 Ų2740.1 Ų40.118%0.18219%0.188CC..  trans-101.1152.1178-620000111.5Y93 T97 A100 A101 M104 S146Y93-C95 PolarHBondContact O-N 3.43Å; C95-T97 VanDerWaalsContact C-N 3.32Å; C95-T97 WeakPolarHBondContact CB-O 3.4Å; C95-A100 HydrophobicContact CB-CB 4.4Å; C95-A101 HydrophobicContact CB-CB 3.97Å; C95-A101 VanDerWaalsContact SG-CA 3.55Å; C95-M104 PolarHBondContact SG-SD 3.02Å; C95-S146 WeakPolarHBondContact CA-O 3.24Å
96R97.7Very high98Very high178 Ų17839.2 Ų39.267%0.67218%0.183SC*.SBendtrans-72.1-25.2170-63.1-174-176.4173.9-7.5113.6S146 E147 M148R96-S146 PolarHBondContact N-O 3.26Å; R96-S146 VanDerWaalsContact N-O 3.11Å; R96-E147 VanDerWaalsContact CD-O 3.26Å; R96-E147 WeakPolarHBondContact CD-O 3.45Å; R96-E147 PolarHBondContact NE-O 3.4Å; R96-E147 PolarHBondContact NH1-O 2.78Å; R96-E147 VanDerWaalsContact NH1-O 3.12Å; R96-M148 WeakPolarHBondContact CB-O 3.2Å
97T97.5Very high98.1Very high9 Ų935.4 Ų35.46%0.05517%0.169CC..SBendtrans-125.7143.6178.873.60000111.3C95 Q99 A100 A101 E150C95-T97 VanDerWaalsContact C-N 3.32Å; C95-T97 WeakPolarHBondContact CB-O 3.4Å; T97-Q99 VanDerWaalsContact C-N 3.29Å; T97-Q99 PolarHBondContact O-N 3.48Å; T97-A100 PolarHBondContact O-N 3.05Å; T97-A100 VanDerWaalsContact OG1-CB 3.25Å; T97-A100 WeakPolarHBondContact OG1-CB 3.45Å; T97-A100 PolarHBondContact OG1-N 2.87Å; T97-A101 PolarHBondContact O-N 3.34Å; T97-A101 VanDerWaalsContact O-N 3.12Å; T97-E150 HydrophobicContact CG2-CG 3.67Å
98R97.8Very high98.1Very high136 Ų13634.7 Ų34.751%0.51316%0.163SC..Hα-helixtrans-65.4-33.3175.8-72.1-177.5168.7-174-5.6112.5A100 A101 A102 L607R98-A100 VanDerWaalsContact C-N 3.33Å; R98-A100 PolarHBondContact O-N 2.91Å; R98-A101 PolarHBondContact O-N 2.7Å; R98-A102 WeakPolarHBondContact O-CB 3.45Å; R98-A102 PolarHBondContact O-N 2.92Å; R98-L607 HydrophobicContact CB-CD2 4.05Å
99Q98.4Very high98.1Very high15 Ų1533.4 Ų33.47%0.0716%0.158CC..Hα-helixtrans-61.5-40.9175.3-71.1-175.3-43.500112.2T97 A102 M103 R173 T584 L607 R617T97-Q99 VanDerWaalsContact C-N 3.29Å; T97-Q99 PolarHBondContact O-N 3.48Å; Q99-A102 PolarHBondContact O-N 3.46Å; Q99-M103 PolarHBondContact O-N 3.35Å; Q99-M103 VanDerWaalsContact O-N 3.15Å; Q99-R173 HydrophobicContact CB-CG 3.66Å; Q99-R173 HydrophobicContact CG-CG 4.42Å; Q99-T584 HydrophobicContact CB-CG2 3.59Å; Q99-T584 HydrophobicContact CG-CG2 3.7Å; Q99-T584 PolarHBondContact NE2-OG1 3.11Å; Q99-L607 HydrophobicContact CB-CD2 4.45Å; Q99-L607 HydrophobicContact CG-CB 4.32Å; Q99-L607 HydrophobicContact CG-CD2 3.88Å; Q99-R617 VanDerWaalsContact NE2-NH1 3.15Å
100A98.7Very high98.1Very high0 Ų031.6 Ų31.60%015%0.146CC..Hα-helixtrans-71.6-38.4175.600000112.7C95 T97 R98 A102 M103 M104 L145 M148C95-A100 HydrophobicContact CB-CB 4.4Å; T97-A100 PolarHBondContact O-N 3.05Å; T97-A100 VanDerWaalsContact OG1-CB 3.25Å; T97-A100 WeakPolarHBondContact OG1-CB 3.45Å; T97-A100 PolarHBondContact OG1-N 2.87Å; R98-A100 VanDerWaalsContact C-N 3.33Å; R98-A100 PolarHBondContact O-N 2.91Å; A100-A102 VanDerWaalsContact C-N 3.32Å; A100-A102 PolarHBondContact O-N 2.85Å; A100-M103 HydrophobicContact CB-CE 4.37Å; A100-M103 PolarHBondContact O-N 2.97Å; A100-M104 PolarHBondContact O-N 3.04Å; A100-L145 HydrophobicContact CB-CB 4.3Å; A100-L145 HydrophobicContact CB-CD2 4.26Å; A100-L145 WeakPolarHBondContact CB-O 3.34Å; A100-M148 HydrophobicContact CB-CG 3.86Å; A100-M148 HydrophobicContact CB-SD 3.8Å
101A98.7Very high98.1Very high4 Ų431.5 Ų31.53%0.03315%0.146CC..Hα-helixtrans-58-43.917200000112I90 C95 T97 R98 M103 M104 L105I90-A101 HydrophobicContact CD1-CB 4.37Å; I90-A101 HydrophobicContact CG1-CB 3.74Å; C95-A101 HydrophobicContact CB-CB 3.97Å; C95-A101 VanDerWaalsContact SG-CA 3.55Å; T97-A101 PolarHBondContact O-N 3.34Å; T97-A101 VanDerWaalsContact O-N 3.12Å; R98-A101 PolarHBondContact O-N 2.7Å; A101-M103 PolarHBondContact O-N 2.69Å; A101-M104 PolarHBondContact O-N 3.04Å; A101-L105 PolarHBondContact O-N 3.35Å
102A98.8Very high98.1Very high1 Ų126.3 Ų26.31%0.00812%0.118CC..Hα-helixtrans-60.4-43.5175.200000111.8I90 R98 Q99 A100 M104 L105 M106 V539 L607I90-A102 HydrophobicContact CD1-CB 4.02Å; R98-A102 WeakPolarHBondContact O-CB 3.45Å; R98-A102 PolarHBondContact O-N 2.92Å; Q99-A102 PolarHBondContact O-N 3.46Å; A100-A102 VanDerWaalsContact C-N 3.32Å; A100-A102 PolarHBondContact O-N 2.85Å; A102-M104 PolarHBondContact O-N 3.37Å; A102-L105 WeakPolarHBondContact O-CB 3.36Å; A102-L105 PolarHBondContact O-N 3.41Å; A102-M106 WeakPolarHBondContact O-CG 3.36Å; A102-M106 PolarHBondContact O-N 3.09Å; A102-V539 HydrophobicContact CB-CG2 3.81Å; A102-L607 HydrophobicContact CB-CD1 3.78Å; A102-L607 HydrophobicContact CB-CD2 4.42Å
103M98.8Very high97.9Very high2 Ų224.8 Ų24.81%0.0112%0.117CC..Hα-helixtrans-63.3-40.8175.1-71.6-173.3-68.400112.5Q99 A100 A101 L105 M106 I107 L145 M148 R173 A174 W585Q99-M103 PolarHBondContact O-N 3.35Å; Q99-M103 VanDerWaalsContact O-N 3.15Å; A100-M103 HydrophobicContact CB-CE 4.37Å; A100-M103 PolarHBondContact O-N 2.97Å; A101-M103 PolarHBondContact O-N 2.69Å; M103-L105 VanDerWaalsContact C-N 3.34Å; M103-L105 PolarHBondContact O-N 3.5Å; M103-M106 PolarHBondContact O-N 3.4Å; M103-I107 WeakPolarHBondContact O-CB 3.26Å; M103-I107 VanDerWaalsContact O-CG1 3.28Å; M103-I107 WeakPolarHBondContact O-CG1 3.33Å; M103-I107 PolarHBondContact O-N 3.46Å; M103-L145 HydrophobicContact CB-CD1 4.07Å; M103-L145 HydrophobicContact CB-CD2 4.43Å; M103-L145 HydrophobicContact CE-CD2 3.41Å; M103-L145 VanDerWaalsContact CE-CD2 3.41Å; M103-L145 HydrophobicContact SD-CD2 4.38Å; M103-M148 HydrophobicContact CE-SD 4.36Å; M103-R173 HydrophobicContact CE-CB 3.33Å; M103-R173 HydrophobicContact CE-CG 4.36Å; M103-R173 HydrophobicContact SD-CB 4.36Å; M103-A174 HydrophobicContact CE-CB 4.37Å; M103-A174 HydrophobicContact SD-CB 3.72Å; M103-W585 HydrophobicContact CG-CD2 4.02Å; M103-W585 HydrophobicContact CG-CE3 3.47Å; M103-W585 VanDerWaalsContact CG-CE3 3.47Å; M103-W585 HydrophobicContact CG-CH2 4.43Å; M103-W585 HydrophobicContact CG-CZ3 3.72Å; M103-W585 HydrophobicContact SD-CB 3.93Å; M103-W585 HydrophobicContact SD-CD2 4.19Å; M103-W585 HydrophobicContact SD-CE3 3.93Å; M103-W585 HydrophobicContact SD-CG 4.24Å
104M98.8Very high97.6Very high0 Ų027.1 Ų27.10%014%0.139CC..Hα-helixtrans-60.8-42.7174.7-73.6-177.972.400111.9L7 Y93 C95 A100 A101 A102 M106 I107 M108 M142 L145L7-M104 HydrophobicContact CB-CE 4.45Å; Y93-M104 HydrophobicContact CD1-CB 3.52Å; Y93-M104 HydrophobicContact CD1-CE 4Å; Y93-M104 HydrophobicContact CD1-CG 4.46Å; Y93-M104 HydrophobicContact CD1-SD 4.24Å; Y93-M104 HydrophobicContact CE1-CB 3.7Å; Y93-M104 HydrophobicContact CG-CB 4.31Å; C95-M104 PolarHBondContact SG-SD 3.02Å; A100-M104 PolarHBondContact O-N 3.04Å; A101-M104 PolarHBondContact O-N 3.04Å; A102-M104 PolarHBondContact O-N 3.37Å; M104-M106 VanDerWaalsContact C-N 3.34Å; M104-M106 PolarHBondContact O-N 3.36Å; M104-I107 PolarHBondContact O-N 3.11Å; M104-M108 VanDerWaalsContact O-CG 3.31Å; M104-M108 WeakPolarHBondContact O-CG 3.45Å; M104-M108 PolarHBondContact O-N 3.47Å; M104-M142 HydrophobicContact CB-CE 3.87Å; M104-M142 HydrophobicContact CB-SD 4.32Å; M104-M142 HydrophobicContact CE-CB 4.07Å; M104-M142 HydrophobicContact CE-CE 3.37Å; M104-M142 HydrophobicContact CE-CG 4.49Å; M104-M142 HydrophobicContact CE-SD 4.01Å; M104-M142 HydrophobicContact CG-CE 3.92Å; M104-M142 HydrophobicContact CG-SD 3.88Å; M104-M142 HydrophobicContact SD-CE 4.46Å; M104-L145 HydrophobicContact CG-CB 3.73Å; M104-L145 HydrophobicContact CG-CD1 3.65Å; M104-L145 HydrophobicContact CG-CG 4.36Å; M104-L145 HydrophobicContact SD-CB 3.98Å
105L98.8Very high97.4Very high3 Ų325.5 Ų25.52%0.01613%0.128CC..Hα-helixtrans-55.5-50.2173.3-177.5165.1000111.2A87 Y88 Y93 A101 A102 M103 M108 N109 V452 T454A87-L105 HydrophobicContact CB-CD2 3.88Å; A87-L105 HydrophobicContact CB-CG 4.01Å; Y88-L105 WeakPolarHBondContact O-CD1 3.45Å; Y93-L105 HydrophobicContact CD2-CB 4.46Å; Y93-L105 HydrophobicContact CE2-CB 3.73Å; Y93-L105 HydrophobicContact CE2-CD1 4.44Å; Y93-L105 HydrophobicContact CE2-CG 4.22Å; Y93-L105 WeakPolarHBondContact OH-CA 3.49Å; A101-L105 PolarHBondContact O-N 3.35Å; A102-L105 WeakPolarHBondContact O-CB 3.36Å; A102-L105 PolarHBondContact O-N 3.41Å; M103-L105 VanDerWaalsContact C-N 3.34Å; M103-L105 PolarHBondContact O-N 3.5Å; L105-M108 PolarHBondContact O-N 3.37Å; L105-N109 WeakPolarHBondContact O-CB 3.43Å; L105-N109 PolarHBondContact O-N 3.01Å; L105-V452 HydrophobicContact CD2-CG1 4.25Å; L105-T454 HydrophobicContact CD1-CG2 4.26Å
106M98.9Very high97.1Very high0 Ų024.5 Ų24.50%012%0.122CC..Hα-helixtrans-68.1-39.1-176.8-64.9-62.6-63.400113A102 M103 M104 N109 N110 Y210 C211 V452 V539 W585A102-M106 WeakPolarHBondContact O-CG 3.36Å; A102-M106 PolarHBondContact O-N 3.09Å; M103-M106 PolarHBondContact O-N 3.4Å; M104-M106 VanDerWaalsContact C-N 3.34Å; M104-M106 PolarHBondContact O-N 3.36Å; M106-N109 WeakPolarHBondContact O-CB 3.34Å; M106-N109 PolarHBondContact O-N 3.22Å; M106-N110 PolarHBondContact O-N 2.99Å; M106-N110 VanDerWaalsContact O-N 3.1Å; M106-Y210 WeakPolarHBondContact CB-O 3.36Å; M106-Y210 WeakPolarHBondContact CE-O 3.14Å; M106-C211 HydrophobicContact CE-CB 4.03Å; M106-V452 HydrophobicContact CE-CG2 3.77Å; M106-V452 HydrophobicContact SD-CB 3.89Å; M106-V452 HydrophobicContact SD-CG1 3.96Å; M106-V452 HydrophobicContact SD-CG2 3.74Å; M106-V539 HydrophobicContact CE-CG1 4.42Å; M106-V539 HydrophobicContact CG-CG1 4.46Å; M106-V539 HydrophobicContact CG-CG2 4.5Å; M106-V539 HydrophobicContact SD-CB 4.42Å; M106-V539 HydrophobicContact SD-CG1 4.25Å; M106-W585 HydrophobicContact CG-CH2 4.08Å; M106-W585 HydrophobicContact CG-CZ2 4.47Å
107I98.9Very high96.6Very high0 Ų019.1 Ų19.10%010%0.104CC..Hα-helixtrans-60.4-48.4173.2-73.4163000110.5M103 M104 N109 N110 L111 V131 F132 F138 V141 M142 L145 Y210M103-I107 WeakPolarHBondContact O-CB 3.26Å; M103-I107 VanDerWaalsContact O-CG1 3.28Å; M103-I107 WeakPolarHBondContact O-CG1 3.33Å; M103-I107 PolarHBondContact O-N 3.46Å; M104-I107 PolarHBondContact O-N 3.11Å; I107-N109 VanDerWaalsContact C-N 3.29Å; I107-N109 PolarHBondContact O-N 3.41Å; I107-N110 PolarHBondContact O-N 3.44Å; I107-L111 HydrophobicContact CG2-CD1 4.5Å; I107-L111 PolarHBondContact O-N 3.1Å; I107-V131 HydrophobicContact CG2-CG1 4.25Å; I107-F132 HydrophobicContact CD1-CZ 4.2Å; I107-F132 HydrophobicContact CG1-CZ 4.43Å; I107-F132 HydrophobicContact CG2-CE2 3.68Å; I107-F132 HydrophobicContact CG2-CZ 4.04Å; I107-F138 HydrophobicContact CG2-CD2 4.22Å; I107-F138 HydrophobicContact CG2-CE2 4Å; I107-V141 HydrophobicContact CD1-CG1 3.83Å; I107-M142 HydrophobicContact CG2-SD 4.26Å; I107-L145 HydrophobicContact CD1-CD1 3.65Å; I107-Y210 HydrophobicContact CD1-CD2 3.95Å; I107-Y210 HydrophobicContact CD1-CE2 4.05Å; I107-Y210 HydrophobicContact CD1-CG 4.25Å; I107-Y210 HydrophobicContact CG1-CD1 3.71Å; I107-Y210 HydrophobicContact CG1-CD2 3.64Å; I107-Y210 HydrophobicContact CG1-CE1 4.18Å; I107-Y210 HydrophobicContact CG1-CE2 4.1Å; I107-Y210 HydrophobicContact CG1-CG 3.42Å; I107-Y210 VanDerWaalsContact CG1-CG 3.42Å
108M98.7Very high96.4Very high0 Ų019.9 Ų19.90%011%0.107CC..Hα-helixtrans-67.6-31-179.7-67.3-174.773.200112.4L4 L7 V83 M85 R86 Y88 Y93 M104 L105 L111 D112 M142L4-M108 HydrophobicContact CD2-CE 3.89Å; L4-M108 HydrophobicContact CD2-SD 4Å; L7-M108 HydrophobicContact CD1-CE 3.91Å; L7-M108 HydrophobicContact CD1-SD 3.75Å; V83-M108 HydrophobicContact CG1-CE 4.21Å; M85-M108 HydrophobicContact SD-CB 3.81Å; M85-M108 HydrophobicContact SD-CE 3.83Å; M85-M108 HydrophobicContact SD-CG 3.75Å; R86-M108 VanDerWaalsContact O-CB 3.24Å; R86-M108 WeakPolarHBondContact O-CB 3.36Å; Y88-M108 HydrophobicContact CD2-CE 4.05Å; Y88-M108 HydrophobicContact CD2-SD 4.45Å; Y88-M108 HydrophobicContact CE2-CE 3.7Å; Y93-M108 HydrophobicContact CE1-SD 3.54Å; Y93-M108 VanDerWaalsContact CE1-SD 3.54Å; Y93-M108 PolarHBondContact OH-SD 3.33Å; M104-M108 VanDerWaalsContact O-CG 3.31Å; M104-M108 WeakPolarHBondContact O-CG 3.45Å; M104-M108 PolarHBondContact O-N 3.47Å; L105-M108 PolarHBondContact O-N 3.37Å; M108-L111 CarbonylContact O-C 3.4Å; M108-L111 PolarHBondContact O-N 3.08Å; M108-D112 PolarHBondContact O-N 3.24Å; M108-M142 HydrophobicContact CG-CE 3.59Å; M108-M142 HydrophobicContact SD-CE 3.72Å
109N98.6Very high96.2Very high0 Ų013.7 Ų13.70%08%0.084CC..Hα-helixtrans-61.4-46.8171.2-175.975.8000111.9A87 L105 M106 I107 L111 D112 V115 Y212 S506A87-N109 HydrophobicContact CB-CB 4.14Å; L105-N109 WeakPolarHBondContact O-CB 3.43Å; L105-N109 PolarHBondContact O-N 3.01Å; M106-N109 WeakPolarHBondContact O-CB 3.34Å; M106-N109 PolarHBondContact O-N 3.22Å; I107-N109 VanDerWaalsContact C-N 3.29Å; I107-N109 PolarHBondContact O-N 3.41Å; N109-L111 PolarHBondContact O-N 3.47Å; N109-L111 VanDerWaalsContact O-N 3.15Å; N109-D112 WeakPolarHBondContact O-CB 3.31Å; N109-D112 PolarHBondContact O-N 2.9Å; N109-D112 VanDerWaalsContact O-N 3.14Å; N109-V115 WeakPolarHBondContact O-CB 3.35Å; N109-Y212 PolarHBondContact ND2-O 3.48Å; N109-S506 VanDerWaalsContact CG-OG 3.27Å; N109-S506 PolarHBondContact ND2-OG 3.49Å; N109-S506 VanDerWaalsContact OD1-CB 3.25Å; N109-S506 WeakPolarHBondContact OD1-CB 3.44Å; N109-S506 PolarHBondContact OD1-N 3.48Å; N109-S506 PolarHBondContact OD1-OG 3.44Å
110N98.4Very high96.1Very high0 Ų014.4 Ų14.40%09%0.088CC..Hα-helixtrans-62-20.8178.7-88.929.3000113.6M106 I107 A116 T124 V131 T206 A207 Y212M106-N110 PolarHBondContact O-N 2.99Å; M106-N110 VanDerWaalsContact O-N 3.1Å; I107-N110 PolarHBondContact O-N 3.44Å; N110-A116 WeakPolarHBondContact O-CB 3.37Å; N110-T124 HydrophobicContact CB-CG2 4.37Å; N110-T124 WeakPolarHBondContact O-CG2 3.49Å; N110-T124 PolarHBondContact O-OG1 3.04Å; N110-V131 HydrophobicContact CB-CG2 3.75Å; N110-T206 PolarHBondContact ND2-O 2.99Å; N110-A207 PolarHBondContact ND2-O 3.43Å; N110-Y212 WeakPolarHBondContact OD1-CA 3.33Å; N110-Y212 WeakPolarHBondContact OD1-CB 3.39Å; N110-Y212 PolarHBondContact OD1-N 3.34Å; N110-Y212 PolarHBondContact OD1-O 3.07Å
111L98.1Very high96.1Very high1 Ų114.4 Ų14.41%0.0059%0.088CC..THydrogen-bonded Turntrans-106.40.8179.7-66.2176.8000113.4M85 I107 M108 N109 L122 V131 W135 F138M85-L111 HydrophobicContact CE-CB 4.43Å; M85-L111 HydrophobicContact CE-CD1 4.35Å; M85-L111 VanDerWaalsContact CG-C 3.43Å; M85-L111 HydrophobicContact CG-CB 3.5Å; M85-L111 WeakPolarHBondContact CG-O 3.35Å; M85-L111 HydrophobicContact SD-CB 3.9Å; I107-L111 HydrophobicContact CG2-CD1 4.5Å; I107-L111 PolarHBondContact O-N 3.1Å; M108-L111 CarbonylContact O-C 3.4Å; M108-L111 PolarHBondContact O-N 3.08Å; N109-L111 PolarHBondContact O-N 3.47Å; N109-L111 VanDerWaalsContact O-N 3.15Å; L111-L122 HydrophobicContact CD2-CB 3.96Å; L111-L122 HydrophobicContact CD2-CG 4.4Å; L111-V131 HydrophobicContact CD1-CB 4.5Å; L111-V131 HydrophobicContact CD1-CG1 4.38Å; L111-V131 HydrophobicContact CD2-CB 3.91Å; L111-V131 HydrophobicContact CD2-CG2 3.52Å; L111-V131 HydrophobicContact CG-CB 4.21Å; L111-V131 HydrophobicContact CG-CG1 4.34Å; L111-V131 HydrophobicContact CG-CG2 3.88Å; L111-W135 HydrophobicContact CD1-CH2 4.28Å; L111-W135 HydrophobicContact CD1-CZ3 4.35Å; L111-F138 HydrophobicContact CD1-CD2 3.62Å; L111-F138 HydrophobicContact CD1-CE2 3.78Å
112D96.9Very high96.1Very high15 Ų1514.2 Ų14.28%0.089%0.086CC..  trans-60.2127.6176.9-172.6-36.3000109.4M85 R86 M108 N109 A114 V115 A116M85-D112 WeakPolarHBondContact O-CA 3.37Å; R86-D112 WeakPolarHBondContact CA-OD2 3.3Å; R86-D112 WeakPolarHBondContact CB-OD2 3.34Å; M108-D112 PolarHBondContact O-N 3.24Å; N109-D112 WeakPolarHBondContact O-CB 3.31Å; N109-D112 PolarHBondContact O-N 2.9Å; N109-D112 VanDerWaalsContact O-N 3.14Å; D112-A114 PolarHBondContact O-N 3.19Å; D112-A114 WeakPolarHBondContact OD1-CB 3.4Å; D112-A114 PolarHBondContact OD1-N 2.82Å; D112-V115 HydrophobicContact CB-CB 4.04Å; D112-V115 HydrophobicContact CB-CG2 3.89Å; D112-V115 CarbonylContact O-C 3.59Å; D112-V115 WeakPolarHBondContact O-CA 3.3Å; D112-V115 PolarHBondContact O-N 3.47Å; D112-A116 WeakPolarHBondContact O-CB 3.46Å; D112-A116 PolarHBondContact O-N 2.92Å
113P93.3Very high95.9Very high69 Ų6914.2 Ų14.245%0.4489%0.086SC..THydrogen-bonded Turntrans-56.7-21.5177.2-26.935.6000114.9M85 P119M85-P113 VanDerWaalsContact O-CD 3.27Å; M85-P113 WeakPolarHBondContact O-CD 3.28Å; P113-P119 HydrophobicContact CB-CG 4.18Å; P113-P119 HydrophobicContact CG-CB 4.3Å; P113-P119 HydrophobicContact CG-CG 4.34Å
114A90.1Very high95.7Very high61 Ų6114.1 Ų14.150%0.5049%0.085SC..THydrogen-bonded Turntrans-75.1-25.917200000112.8D112 V504D112-A114 PolarHBondContact O-N 3.19Å; D112-A114 WeakPolarHBondContact OD1-CB 3.4Å; D112-A114 PolarHBondContact OD1-N 2.82Å; A114-V504 HydrophobicContact CB-CG1 3.86Å; A114-V504 VanDerWaalsContact O-CG1 3.24Å; A114-V504 WeakPolarHBondContact O-CG1 3.48Å
115V91.1Very high95.2Very high15 Ų1514.3 Ų14.39%0.0919%0.086CC..THydrogen-bonded Turntrans-101.4-49.5-174.7177.30000111.8N109 D112 Y212 V504N109-V115 WeakPolarHBondContact O-CB 3.35Å; D112-V115 HydrophobicContact CB-CB 4.04Å; D112-V115 HydrophobicContact CB-CG2 3.89Å; D112-V115 CarbonylContact O-C 3.59Å; D112-V115 WeakPolarHBondContact O-CA 3.3Å; D112-V115 PolarHBondContact O-N 3.47Å; V115-Y212 HydrophobicContact CG1-CD1 3.48Å; V115-Y212 VanDerWaalsContact CG1-CD1 3.48Å; V115-Y212 HydrophobicContact CG1-CE1 3.8Å; V115-V504 HydrophobicContact CG2-CG1 4Å
116A91.9Very high94.4Very high6 Ų614.6 Ų14.65%0.059%0.09CC..  trans-76144.4-172.800000112.7N110 D112 P119 T124N110-A116 WeakPolarHBondContact O-CB 3.37Å; D112-A116 WeakPolarHBondContact O-CB 3.46Å; D112-A116 PolarHBondContact O-N 2.92Å; A116-P119 HydrophobicContact CB-CB 4.07Å; A116-T124 CarbonylContact C-O 3.34Å
117Q87.8Confident93.6Very high64 Ų6415.9 Ų15.930%0.29910%0.103SC..SBendtrans-71.9-47.9177.3-175.7176.610.700112.2P27 V123 T124P27-Q117 VanDerWaalsContact CG-O 3.28Å; P27-Q117 WeakPolarHBondContact CG-O 3.38Å; Q117-V123 PolarHBondContact N-O 2.84Å; Q117-T124 WeakPolarHBondContact CB-O 3.29Å; Q117-T124 PolarHBondContact N-O 3.43Å
118F92.5Very high93.2Very high25 Ų2516.2 Ų16.211%0.1111%0.105CC..BIsolated β-bridgetrans-13381.3176.4-47.8-60.3000109.1P27 H28 A29 Q120 E121 L122 V123P27-F118 HydrophobicContact CB-CD1 4.1Å; P27-F118 HydrophobicContact CB-CE1 4.35Å; H28-F118 WeakPolarHBondContact O-CD1 3.21Å; H28-F118 WeakPolarHBondContact O-CE1 3.34Å; A29-F118 HydrophobicContact CB-CB 4.1Å; A29-F118 HydrophobicContact CB-CD2 3.54Å; A29-F118 HydrophobicContact CB-CE2 4.04Å; A29-F118 HydrophobicContact CB-CG 3.86Å; A29-F118 VanDerWaalsContact N-CG 3.33Å; F118-Q120 VanDerWaalsContact C-N 3.33Å; F118-Q120 PolarHBondContact O-N 3.22Å; F118-E121 HydrophobicContact CB-CB 4.27Å; F118-E121 CarbonylContact O-C 3.36Å; F118-E121 PolarHBondContact O-N 3.23Å; F118-L122 PolarHBondContact O-N 2.92Å; F118-V123 CarbonylContact C-O 3.59Å; F118-V123 HydrophobicContact CB-CB 3.98Å; F118-V123 HydrophobicContact CB-CG2 4.39Å; F118-V123 HydrophobicContact CD2-CB 3.98Å; F118-V123 HydrophobicContact CD2-CG1 3.95Å; F118-V123 HydrophobicContact CD2-CG2 4.23Å; F118-V123 HydrophobicContact CG-CB 4.45Å; F118-V123 PolarHBondContact N-O 3.49Å; F118-V123 PolarHBondContact O-N 2.96Å
119P94.7Very high93Very high7 Ų716.2 Ų16.25%0.04511%0.105CC..G310 helixtrans-62.1-36.2-168.222.3-33.2000113.1V26 P113 A116 E121 L122 W135V26-P119 HydrophobicContact CB-CG 4.36Å; P113-P119 HydrophobicContact CB-CG 4.18Å; P113-P119 HydrophobicContact CG-CB 4.3Å; P113-P119 HydrophobicContact CG-CG 4.34Å; A116-P119 HydrophobicContact CB-CB 4.07Å; P119-E121 VanDerWaalsContact C-N 3.35Å; P119-L122 PolarHBondContact O-N 3.33Å; P119-W135 WeakPolarHBondContact O-CZ2 3.43Å
120Q96.4Very high92.9Very high30 Ų3016.2 Ų16.214%0.1411%0.105CC..G310 helixtrans-75.3-21.7-179.6-74.2-167.5-17.100113.9D23 V26 H28 Y77 F118 L122 W135D23-Q120 VanDerWaalsContact CB-NE2 3.27Å; V26-Q120 HydrophobicContact CG2-CG 3.99Å; H28-Q120 PolarHBondContact CE1-OE1 3.02Å; Y77-Q120 HydrophobicContact CE1-CB 4.12Å; Y77-Q120 WeakPolarHBondContact CE1-O 3.43Å; F118-Q120 VanDerWaalsContact C-N 3.33Å; F118-Q120 PolarHBondContact O-N 3.22Å; Q120-L122 VanDerWaalsContact C-N 3.32Å; Q120-W135 PolarHBondContact O-NE1 3.49Å
121E97.4Very high92.9Very high0 Ų016.2 Ų16.20%011%0.105CC..G310 helixtrans-93.99.9170.7-70.875.9-14100112.8R22 H28 A29 Y75 Y77 F118 P119 V123 Q130R22-E121 IonicContact CZ-OE1 3.76Å; R22-E121 IonicContact NE-OE1 2.72Å; R22-E121 PolarHBondContact NE-OE1 3.06Å; R22-E121 IonicContact NH2-OE1 3.37Å; H28-E121 WeakPolarHBondContact CA-OE2 3.41Å; H28-E121 IonicContact CE1-OE1 2.69Å; H28-E121 IonicContact CG-OE1 2.68Å; H28-E121 IonicContact CG-OE2 3.58Å; H28-E121 IonicContact ND1-OE1 3.54Å; H28-E121 PolarHBondContact ND1-OE1 3.32Å; H28-E121 IonicContact ND1-OE2 2.96Å; H28-E121 PolarHBondContact ND1-OE2 3.32Å; A29-E121 HydrophobicContact CB-CB 3.96Å; A29-E121 HydrophobicContact CB-CG 3.84Å; A29-E121 PolarHBondContact N-OE2 3.16Å; Y75-E121 HydrophobicContact CD1-CB 4Å; Y75-E121 HydrophobicContact CD1-CG 4.05Å; Y75-E121 HydrophobicContact CD2-CG 4.29Å; Y75-E121 HydrophobicContact CE1-CB 3.51Å; Y75-E121 HydrophobicContact CE1-CG 3.63Å; Y75-E121 HydrophobicContact CE2-CG 3.89Å; Y75-E121 HydrophobicContact CG-CG 4.36Å; Y77-E121 WeakPolarHBondContact CE1-OE1 3.45Å; Y77-E121 WeakPolarHBondContact OH-CG 3.4Å; Y77-E121 PolarHBondContact OH-OE1 2.82Å; F118-E121 HydrophobicContact CB-CB 4.27Å; F118-E121 CarbonylContact O-C 3.36Å; F118-E121 PolarHBondContact O-N 3.23Å; P119-E121 VanDerWaalsContact C-N 3.35Å; E121-V123 HydrophobicContact CB-CG2 4.16Å; E121-V123 PolarHBondContact O-N 3.33Å; E121-Q130 PolarHBondContact O-NE2 3.38Å
122L98.3Very high92.9Very high0 Ų016.2 Ų16.20%011%0.105CC..THydrogen-bonded Turntrans59.424.4179.3-51.395.5000113.8Y75 L111 F118 P119 Q120 Q130 V131 F132 W135 F138Y75-L122 HydrophobicContact CD1-CD1 4.36Å; L111-L122 HydrophobicContact CD2-CB 3.96Å; L111-L122 HydrophobicContact CD2-CG 4.4Å; F118-L122 PolarHBondContact O-N 2.92Å; P119-L122 PolarHBondContact O-N 3.33Å; Q120-L122 VanDerWaalsContact C-N 3.32Å; L122-Q130 CarbonylContact O-C 3.51Å; L122-Q130 WeakPolarHBondContact O-CA 3.29Å; L122-V131 PolarHBondContact O-N 3.43Å; L122-F132 WeakPolarHBondContact CB-O 3.44Å; L122-F132 HydrophobicContact CD2-CB 3.85Å; L122-F132 HydrophobicContact CD2-CD2 4.08Å; L122-F132 HydrophobicContact CD2-CG 4.47Å; L122-W135 HydrophobicContact CD1-CD2 4.17Å; L122-W135 HydrophobicContact CD1-CG 4.18Å; L122-W135 HydrophobicContact CD1-CZ2 4.34Å; L122-W135 HydrophobicContact CD2-CD2 4.02Å; L122-W135 HydrophobicContact CD2-CE3 4.1Å; L122-W135 HydrophobicContact CD2-CH2 4.43Å; L122-W135 HydrophobicContact CD2-CZ2 4.35Å; L122-W135 HydrophobicContact CD2-CZ3 4.31Å; L122-W135 HydrophobicContact CG-CD2 4.27Å; L122-W135 HydrophobicContact CG-CH2 4.43Å; L122-W135 HydrophobicContact CG-CZ2 3.97Å; L122-F138 HydrophobicContact CD2-CB 4.29Å
123V96Very high93Very high0 Ų015.5 Ų15.50%010%0.101CC..EExtended strand (participates in β ladder)trans-94116.6178.6-179.30000109.7Q117 F118 E121 G129 Q130Q117-V123 PolarHBondContact N-O 2.84Å; F118-V123 CarbonylContact C-O 3.59Å; F118-V123 HydrophobicContact CB-CB 3.98Å; F118-V123 HydrophobicContact CB-CG2 4.39Å; F118-V123 HydrophobicContact CD2-CB 3.98Å; F118-V123 HydrophobicContact CD2-CG1 3.95Å; F118-V123 HydrophobicContact CD2-CG2 4.23Å; F118-V123 HydrophobicContact CG-CB 4.45Å; F118-V123 PolarHBondContact N-O 3.49Å; F118-V123 PolarHBondContact O-N 2.96Å; E121-V123 HydrophobicContact CB-CG2 4.16Å; E121-V123 PolarHBondContact O-N 3.33Å; V123-G129 CarbonylContact C-O 3.53Å; V123-G129 WeakPolarHBondContact CA-O 3.45Å; V123-Q130 HydrophobicContact CB-CG 4.37Å; V123-Q130 HydrophobicContact CG2-CG 3.63Å
124T94.2Very high93.2Very high1 Ų112.4 Ų12.41%0.0068%0.081CC..EExtended strand (participates in β ladder)trans-79.3-47.6175.8-530000111.4N110 A116 Q117 G129 V131 Y212N110-T124 HydrophobicContact CB-CG2 4.37Å; N110-T124 WeakPolarHBondContact O-CG2 3.49Å; N110-T124 PolarHBondContact O-OG1 3.04Å; A116-T124 CarbonylContact C-O 3.34Å; Q117-T124 WeakPolarHBondContact CB-O 3.29Å; Q117-T124 PolarHBondContact N-O 3.43Å; T124-G129 PolarHBondContact N-O 3.2Å; T124-V131 WeakPolarHBondContact OG1-CG2 3.25Å; T124-Y212 HydrophobicContact CG2-CD1 3.37Å; T124-Y212 HydrophobicContact CG2-CE1 4.07Å; T124-Y212 HydrophobicContact CG2-CG 3.72Å
125Y88.4Confident93.6Very high3 Ų39.8 Ų9.81%0.0126%0.058CC..EExtended strand (participates in β ladder)trans-164.5177.6179.168.1-78.2000112.7G127 G129 Q204 T206 A207 Y212 M252Y125-G127 VanDerWaalsContact C-N 3.29Å; Y125-G127 PolarHBondContact O-N 2.76Å; Y125-G129 WeakPolarHBondContact O-CA 3.37Å; Y125-G129 PolarHBondContact O-N 2.94Å; Y125-Q204 HydrophobicContact CD2-CG 4.25Å; Y125-Q204 HydrophobicContact CE2-CB 4.33Å; Y125-Q204 HydrophobicContact CE2-CG 3.64Å; Y125-Q204 PolarHBondContact OH-OE1 3.38Å; Y125-T206 WeakPolarHBondContact CE1-OG1 3.41Å; Y125-T206 PolarHBondContact OH-N 2.94Å; Y125-T206 PolarHBondContact OH-OG1 2.8Å; Y125-A207 HydrophobicContact CD1-CB 4.13Å; Y125-A207 HydrophobicContact CE1-CB 3.83Å; Y125-Y212 AromaticContact CD1-CD2 3.79Å; Y125-Y212 HydrophobicContact CD1-CD2 3.79Å; Y125-Y212 AromaticContact CD1-CE2 3.93Å; Y125-Y212 HydrophobicContact CD1-CE2 3.93Å; Y125-Y212 HydrophobicContact CD1-CG 4.14Å; Y125-Y212 AromaticContact CE1-CD2 3.59Å; Y125-Y212 HydrophobicContact CE1-CD2 3.59Å; Y125-Y212 HydrophobicContact CE1-CE2 4.04Å; Y125-Y212 HydrophobicContact CE1-CG 4.11Å; Y125-Y212 HydrophobicContact CG-CE2 4.22Å; Y125-M252 HydrophobicContact CD2-CE 3.95Å; Y125-M252 HydrophobicContact CD2-CG 3.97Å; Y125-M252 HydrophobicContact CD2-SD 3.67Å; Y125-M252 HydrophobicContact CE2-CE 4.19Å; Y125-M252 HydrophobicContact CE2-CG 4.37Å; Y125-M252 HydrophobicContact CE2-SD 3.6Å; Y125-M252 VanDerWaalsContact CE2-SD 3.6Å
126G82.1Confident94Very high9 Ų99 Ų99%0.0935%0.053CC..THydrogen-bonded Turntrans75.116.7175.600000113.9N128 H347G126-N128 PolarHBondContact O-N 2.72Å; G126-N128 PolarHBondContact O-OD1 2.86Å; G126-H347 PolarHBondContact O-NE2 2.68Å
127G82.9Confident94.3Very high27 Ų278.8 Ų8.828%0.2785%0.051SC..THydrogen-bonded Turntrans79.8-36.9-17800000113.9Y125Y125-G127 VanDerWaalsContact C-N 3.29Å; Y125-G127 PolarHBondContact O-N 2.76Å
128N88.9Confident94.8Very high8 Ų85.8 Ų5.84%0.0434%0.037CC..THydrogen-bonded Turntrans-143.510-177.562.7-8.8000115G126 Q130 Y191 Y202 N348G126-N128 PolarHBondContact O-N 2.72Å; G126-N128 PolarHBondContact O-OD1 2.86Å; N128-Q130 PolarHBondContact O-N 3.37Å; N128-Y191 PolarHBondContact ND2-OH 3.42Å; N128-Y202 WeakPolarHBondContact OD1-CD1 3.36Å; N128-Y202 WeakPolarHBondContact OD1-CE1 3.23Å; N128-N348 PolarHBondContact ND2-ND2 3.16Å; N128-N348 PolarHBondContact OD1-ND2 2.92Å; N128-N348 VanDerWaalsContact OD1-ND2 3.1Å
129G94.4Very high95.1Very high0 Ų05.7 Ų5.70%04%0.036CC..EExtended strand (participates in β ladder)trans-72.5104.6174.500000111.2V123 T124 Y125 Y202 A207V123-G129 CarbonylContact C-O 3.53Å; V123-G129 WeakPolarHBondContact CA-O 3.45Å; T124-G129 PolarHBondContact N-O 3.2Å; Y125-G129 WeakPolarHBondContact O-CA 3.37Å; Y125-G129 PolarHBondContact O-N 2.94Å; G129-Y202 CarbonylContact C-O 3.51Å; G129-Y202 WeakPolarHBondContact CA-O 3.41Å; G129-A207 WeakPolarHBondContact O-CB 3.36Å
130Q96.5Very high95.3Very high0 Ų06.6 Ų6.60%04%0.04CC..EExtended strand (participates in β ladder)trans-102.9158.2-170.3-75.2177.2-52.800114.2E121 L122 V123 N128 M201 Y202 A207 G208E121-Q130 PolarHBondContact O-NE2 3.38Å; L122-Q130 CarbonylContact O-C 3.51Å; L122-Q130 WeakPolarHBondContact O-CA 3.29Å; V123-Q130 HydrophobicContact CB-CG 4.37Å; V123-Q130 HydrophobicContact CG2-CG 3.63Å; N128-Q130 PolarHBondContact O-N 3.37Å; Q130-M201 VanDerWaalsContact C-CE 3.42Å; Q130-M201 HydrophobicContact CB-CE 3.8Å; Q130-M201 WeakPolarHBondContact O-CE 3.39Å; Q130-Y202 PolarHBondContact N-O 2.78Å; Q130-A207 CarbonylContact O-C 3.51Å; Q130-G208 VanDerWaalsContact O-CA 3.3Å; Q130-G208 WeakPolarHBondContact O-CA 3.46Å; Q130-G208 PolarHBondContact O-N 2.78Å; Q130-G208 VanDerWaalsContact O-N 3.17Å
131V98.6Very high95.4Very high0 Ų05.2 Ų5.20%03%0.034CC..SBendtrans-87.7-44.3169.5-1720000110.7I107 N110 L111 L122 T124 Y210I107-V131 HydrophobicContact CG2-CG1 4.25Å; N110-V131 HydrophobicContact CB-CG2 3.75Å; L111-V131 HydrophobicContact CD1-CB 4.5Å; L111-V131 HydrophobicContact CD1-CG1 4.38Å; L111-V131 HydrophobicContact CD2-CB 3.91Å; L111-V131 HydrophobicContact CD2-CG2 3.52Å; L111-V131 HydrophobicContact CG-CB 4.21Å; L111-V131 HydrophobicContact CG-CG1 4.34Å; L111-V131 HydrophobicContact CG-CG2 3.88Å; L122-V131 PolarHBondContact O-N 3.43Å; T124-V131 WeakPolarHBondContact OG1-CG2 3.25Å; V131-Y210 HydrophobicContact CG1-CD1 3.69Å; V131-Y210 HydrophobicContact CG1-CE1 3.6Å
132F98.8Very high95.5Very high0 Ų05.2 Ų5.20%03%0.034CC..  trans-143.2159.8173.5-54.6-73.2000109.6I107 L122 Q137 F138 V141 M156 G159 M201 Y210I107-F132 HydrophobicContact CD1-CZ 4.2Å; I107-F132 HydrophobicContact CG1-CZ 4.43Å; I107-F132 HydrophobicContact CG2-CE2 3.68Å; I107-F132 HydrophobicContact CG2-CZ 4.04Å; L122-F132 WeakPolarHBondContact CB-O 3.44Å; L122-F132 HydrophobicContact CD2-CB 3.85Å; L122-F132 HydrophobicContact CD2-CD2 4.08Å; L122-F132 HydrophobicContact CD2-CG 4.47Å; F132-Q137 HydrophobicContact CB-CB 4.04Å; F132-Q137 HydrophobicContact CD1-CB 4.21Å; F132-Q137 HydrophobicContact CG-CB 4.31Å; F132-F138 HydrophobicContact CD2-CB 3.77Å; F132-F138 HydrophobicContact CD2-CD2 4.05Å; F132-F138 HydrophobicContact CD2-CG 4.43Å; F132-F138 HydrophobicContact CE2-CB 4.1Å; F132-F138 AromaticContact CE2-CD2 3.75Å; F132-F138 HydrophobicContact CE2-CD2 3.75Å; F132-F138 HydrophobicContact CE2-CG 4.4Å; F132-F138 HydrophobicContact CG-CB 4.45Å; F132-V141 HydrophobicContact CD1-CG2 4.37Å; F132-V141 HydrophobicContact CE1-CB 4.16Å; F132-V141 HydrophobicContact CE1-CG1 4.23Å; F132-V141 HydrophobicContact CE1-CG2 3.61Å; F132-V141 HydrophobicContact CZ-CB 4.06Å; F132-V141 HydrophobicContact CZ-CG1 3.9Å; F132-V141 HydrophobicContact CZ-CG2 4.04Å; F132-M156 HydrophobicContact CD1-CE 4.33Å; F132-M156 HydrophobicContact CE1-CE 3.86Å; F132-G159 WeakPolarHBondContact CD1-O 3.47Å; F132-M201 VanDerWaalsContact CA-SD 3.59Å; F132-Y210 HydrophobicContact CE1-CE1 4.15Å; F132-Y210 AromaticContact CE1-CZ 3.92Å; F132-Y210 VanDerWaalsContact CE1-OH 3.25Å; F132-Y210 WeakPolarHBondContact CE1-OH 3.4Å; F132-Y210 HydrophobicContact CZ-CE1 4.03Å
133S97.9Very high95.5Very high1 Ų110.1 Ų10.11%0.0075%0.052CC..SBendtrans-73.2-30.6176.7-177.40000112.1H73H73-S133 PolarHBondContact CE1-OG 3.13Å; H73-S133 PolarHBondContact NE2-O 3.41Å; H73-S133 PolarHBondContact NE2-OG 3.26Å
134N98.7Very high95.6Very high4 Ų412.7 Ų12.72%0.0216%0.063CC..SBendtrans-155.2167.7-179.558.367.4000112.6I74 Y75 M76 A136 Q137 F138I74-N134 WeakPolarHBondContact O-CB 3.49Å; Y75-N134 WeakPolarHBondContact O-CA 3.37Å; Y75-N134 WeakPolarHBondContact O-CB 3.1Å; M76-N134 HydrophobicContact CE-CB 4.11Å; M76-N134 HydrophobicContact CG-CB 3.98Å; M76-N134 HydrophobicContact SD-CB 3.92Å; N134-A136 VanDerWaalsContact C-N 3.32Å; N134-A136 PolarHBondContact O-N 3.09Å; N134-A136 WeakPolarHBondContact OD1-CB 3.48Å; N134-A136 PolarHBondContact OD1-N 3.25Å; N134-Q137 WeakPolarHBondContact O-CB 3.45Å; N134-Q137 PolarHBondContact O-N 2.86Å; N134-Q137 WeakPolarHBondContact OD1-CG 3.36Å; N134-Q137 PolarHBondContact OD1-N 3.09Å; N134-Q137 VanDerWaalsContact OD1-N 3.08Å; N134-F138 PolarHBondContact O-N 3.47Å
135W98.6Very high95.9Very high5 Ų512.8 Ų12.82%0.0196%0.063CC..Hα-helixtrans-71-20.8-177.5-76.9106000114.7Y75 F79 C80 P81 M85 L111 P119 Q120 L122 F138 R139Y75-W135 PolarHBondContact O-N 3.38Å; F79-W135 HydrophobicContact CB-CB 3.97Å; C80-W135 HydrophobicContact CB-CD2 3.86Å; C80-W135 HydrophobicContact CB-CE3 4.46Å; C80-W135 HydrophobicContact CB-CG 4.03Å; C80-W135 HydrophobicContact CB-CZ2 4.29Å; C80-W135 VanDerWaalsContact SG-CZ2 3.56Å; P81-W135 VanDerWaalsContact CD-CZ3 3.44Å; P81-W135 HydrophobicContact CG-CZ3 4.18Å; M85-W135 HydrophobicContact CE-CH2 3.94Å; M85-W135 HydrophobicContact CE-CZ3 3.85Å; L111-W135 HydrophobicContact CD1-CH2 4.28Å; L111-W135 HydrophobicContact CD1-CZ3 4.35Å; P119-W135 WeakPolarHBondContact O-CZ2 3.43Å; Q120-W135 PolarHBondContact O-NE1 3.49Å; L122-W135 HydrophobicContact CD1-CD2 4.17Å; L122-W135 HydrophobicContact CD1-CG 4.18Å; L122-W135 HydrophobicContact CD1-CZ2 4.34Å; L122-W135 HydrophobicContact CD2-CD2 4.02Å; L122-W135 HydrophobicContact CD2-CE3 4.1Å; L122-W135 HydrophobicContact CD2-CH2 4.43Å; L122-W135 HydrophobicContact CD2-CZ2 4.35Å; L122-W135 HydrophobicContact CD2-CZ3 4.31Å; L122-W135 HydrophobicContact CG-CD2 4.27Å; L122-W135 HydrophobicContact CG-CH2 4.43Å; L122-W135 HydrophobicContact CG-CZ2 3.97Å; W135-F138 HydrophobicContact CE3-CB 3.89Å; W135-F138 AromaticContact CE3-CD1 3.73Å; W135-F138 HydrophobicContact CE3-CD1 3.73Å; W135-F138 HydrophobicContact CE3-CE1 4.47Å; W135-F138 AromaticContact CE3-CG 3.78Å; W135-F138 HydrophobicContact CE3-CG 3.78Å; W135-F138 HydrophobicContact CZ3-CB 4.28Å; W135-F138 AromaticContact CZ3-CD1 3.78Å; W135-F138 HydrophobicContact CZ3-CD1 3.78Å; W135-F138 HydrophobicContact CZ3-CD2 4.05Å; W135-F138 HydrophobicContact CZ3-CE1 4.15Å; W135-F138 HydrophobicContact CZ3-CE2 4.4Å; W135-F138 AromaticContact CZ3-CG 3.75Å; W135-F138 HydrophobicContact CZ3-CG 3.75Å; W135-F138 HydrophobicContact CZ3-CZ 4.46Å; W135-F138 PolarHBondContact O-N 3.28Å; W135-R139 WeakPolarHBondContact O-CG 3.46Å; W135-R139 PolarHBondContact O-N 2.88Å; W135-R139 VanDerWaalsContact O-N 3.09Å
136A98.6Very high96.3Very high0 Ų013.2 Ų13.20%07%0.066CC..Hα-helixtrans-67.7-40.7174.200000111.5L11 Y51 F52 M76 N134 R139 L140L11-A136 HydrophobicContact CD2-CB 3.74Å; Y51-A136 HydrophobicContact CD1-CB 4.33Å; Y51-A136 HydrophobicContact CD2-CB 4.49Å; Y51-A136 HydrophobicContact CG-CB 4.08Å; F52-A136 HydrophobicContact CZ-CB 3.93Å; M76-A136 HydrophobicContact SD-CB 3.39Å; M76-A136 WeakPolarHBondContact SD-CB 3.44Å; N134-A136 VanDerWaalsContact C-N 3.32Å; N134-A136 PolarHBondContact O-N 3.09Å; N134-A136 WeakPolarHBondContact OD1-CB 3.48Å; N134-A136 PolarHBondContact OD1-N 3.25Å; A136-R139 PolarHBondContact O-N 3.48Å; A136-L140 WeakPolarHBondContact O-CG 3.47Å; A136-L140 PolarHBondContact O-N 3.06Å
137Q98.8Very high97.1Very high1 Ų115.8 Ų15.81%0.0058%0.076CC..Hα-helixtrans-59.1-47.5173.4-69.8175.1-11.300111.5Y51 F132 N134 R139 L140 V141 G159Y51-Q137 HydrophobicContact CE1-CG 4.07Å; Y51-Q137 PolarHBondContact OH-NE2 3.25Å; F132-Q137 HydrophobicContact CB-CB 4.04Å; F132-Q137 HydrophobicContact CD1-CB 4.21Å; F132-Q137 HydrophobicContact CG-CB 4.31Å; N134-Q137 WeakPolarHBondContact O-CB 3.45Å; N134-Q137 PolarHBondContact O-N 2.86Å; N134-Q137 WeakPolarHBondContact OD1-CG 3.36Å; N134-Q137 PolarHBondContact OD1-N 3.09Å; N134-Q137 VanDerWaalsContact OD1-N 3.08Å; Q137-R139 VanDerWaalsContact C-N 3.35Å; Q137-R139 PolarHBondContact O-N 3.42Å; Q137-L140 PolarHBondContact O-N 2.71Å; Q137-V141 VanDerWaalsContact O-CG2 3.27Å; Q137-V141 WeakPolarHBondContact O-CG2 3.36Å; Q137-V141 PolarHBondContact O-N 2.93Å; Q137-G159 WeakPolarHBondContact CB-O 3.49Å; Q137-G159 VanDerWaalsContact CD-C 3.42Å; Q137-G159 PolarHBondContact OE1-O 2.93Å
138F98.8Very high97.8Very high0 Ų014.5 Ų14.50%06%0.063CC..Hα-helixtrans-52.7-52.3174.5171-89.4000111.2L7 P81 M85 I107 L111 L122 F132 N134 W135 L140 V141 M142L7-F138 HydrophobicContact CD1-CZ 4.46Å; L7-F138 HydrophobicContact CD2-CE1 3.95Å; L7-F138 HydrophobicContact CD2-CZ 4.33Å; P81-F138 HydrophobicContact CG-CE1 3.8Å; P81-F138 HydrophobicContact CG-CZ 4.37Å; M85-F138 HydrophobicContact CE-CE1 4.18Å; M85-F138 HydrophobicContact CE-CE2 3.76Å; M85-F138 HydrophobicContact CE-CZ 3.5Å; M85-F138 HydrophobicContact SD-CE2 4.33Å; M85-F138 HydrophobicContact SD-CZ 4.31Å; I107-F138 HydrophobicContact CG2-CD2 4.22Å; I107-F138 HydrophobicContact CG2-CE2 4Å; L111-F138 HydrophobicContact CD1-CD2 3.62Å; L111-F138 HydrophobicContact CD1-CE2 3.78Å; L122-F138 HydrophobicContact CD2-CB 4.29Å; F132-F138 HydrophobicContact CD2-CB 3.77Å; F132-F138 HydrophobicContact CD2-CD2 4.05Å; F132-F138 HydrophobicContact CD2-CG 4.43Å; F132-F138 HydrophobicContact CE2-CB 4.1Å; F132-F138 AromaticContact CE2-CD2 3.75Å; F132-F138 HydrophobicContact CE2-CD2 3.75Å; F132-F138 HydrophobicContact CE2-CG 4.4Å; F132-F138 HydrophobicContact CG-CB 4.45Å; N134-F138 PolarHBondContact O-N 3.47Å; W135-F138 HydrophobicContact CE3-CB 3.89Å; W135-F138 AromaticContact CE3-CD1 3.73Å; W135-F138 HydrophobicContact CE3-CD1 3.73Å; W135-F138 HydrophobicContact CE3-CE1 4.47Å; W135-F138 AromaticContact CE3-CG 3.78Å; W135-F138 HydrophobicContact CE3-CG 3.78Å; W135-F138 HydrophobicContact CZ3-CB 4.28Å; W135-F138 AromaticContact CZ3-CD1 3.78Å; W135-F138 HydrophobicContact CZ3-CD1 3.78Å; W135-F138 HydrophobicContact CZ3-CD2 4.05Å; W135-F138 HydrophobicContact CZ3-CE1 4.15Å; W135-F138 HydrophobicContact CZ3-CE2 4.4Å; W135-F138 AromaticContact CZ3-CG 3.75Å; W135-F138 HydrophobicContact CZ3-CG 3.75Å; W135-F138 HydrophobicContact CZ3-CZ 4.46Å; W135-F138 PolarHBondContact O-N 3.28Å; F138-L140 PolarHBondContact O-N 3.33Å; F138-V141 PolarHBondContact O-N 2.83Å; F138-M142 HydrophobicContact CD1-CG 4.27Å; F138-M142 HydrophobicContact CD2-CG 4.33Å; F138-M142 HydrophobicContact CE1-CG 3.83Å; F138-M142 HydrophobicContact CE2-CE 4.33Å; F138-M142 HydrophobicContact CE2-CG 3.9Å; F138-M142 HydrophobicContact CE2-SD 4.1Å; F138-M142 HydrophobicContact CG-CG 4.48Å; F138-M142 HydrophobicContact CZ-CE 4.08Å; F138-M142 HydrophobicContact CZ-CG 3.61Å; F138-M142 HydrophobicContact CZ-SD 4.2Å; F138-M142 VanDerWaalsContact O-CG 3.28Å; F138-M142 WeakPolarHBondContact O-CG 3.49Å; F138-M142 PolarHBondContact O-N 3.45Å
139R98.5Very high98.3Very high23 Ų2316.4 Ų16.49%0.0878%0.075CC..Hα-helixtrans-59.2-44-178.7-73.5-66.5-168.8155.98112.7D6 L11 F79 P81 W135 A136 Q137 R143D6-R139 PolarHBondContact O-NH1 3.3Å; D6-R139 VanDerWaalsContact O-NH1 3.15Å; L11-R139 HydrophobicContact CD2-CB 3.87Å; L11-R139 HydrophobicContact CD2-CG 4.32Å; F79-R139 PolarHBondContact O-NE 2.71Å; P81-R139 VanDerWaalsContact CA-NH2 3.32Å; W135-R139 WeakPolarHBondContact O-CG 3.46Å; W135-R139 PolarHBondContact O-N 2.88Å; W135-R139 VanDerWaalsContact O-N 3.09Å; A136-R139 PolarHBondContact O-N 3.48Å; Q137-R139 VanDerWaalsContact C-N 3.35Å; Q137-R139 PolarHBondContact O-N 3.42Å; R139-R143 PolarHBondContact O-N 3.21Å; R139-R143 VanDerWaalsContact O-N 3.12Å
140L98.8Very high98.4Very high26 Ų2621.7 Ų21.714%0.13610%0.1CC..Hα-helixtrans-67.8-40.5179.2-71.1173.8000112.1L11 Y51 A136 Q137 F138 R143 Y144 P161L11-L140 HydrophobicContact CD1-CD1 4.4Å; L11-L140 HydrophobicContact CD1-CD2 4.24Å; L11-L140 HydrophobicContact CD1-CG 4.31Å; L11-L140 HydrophobicContact CG-CD2 4.2Å; L11-L140 HydrophobicContact CG-CG 4.27Å; Y51-L140 HydrophobicContact CD1-CD1 3.66Å; Y51-L140 HydrophobicContact CE1-CD1 4.13Å; A136-L140 WeakPolarHBondContact O-CG 3.47Å; A136-L140 PolarHBondContact O-N 3.06Å; Q137-L140 PolarHBondContact O-N 2.71Å; F138-L140 PolarHBondContact O-N 3.33Å; L140-R143 WeakPolarHBondContact O-CB 3.47Å; L140-R143 PolarHBondContact O-N 2.95Å; L140-Y144 HydrophobicContact CB-CE2 4.26Å; L140-Y144 WeakPolarHBondContact O-CD2 3.32Å; L140-Y144 PolarHBondContact O-N 2.97Å; L140-P161 HydrophobicContact CB-CG 3.59Å; L140-P161 HydrophobicContact CD1-CG 4.3Å
141V98.9Very high98.5Very high1 Ų127.8 Ų27.81%0.00613%0.128CC..Hα-helixtrans-60.9-48.1175.5170.50000111I107 F132 Q137 F138 R143 Y144 L145 L154 M156 P161I107-V141 HydrophobicContact CD1-CG1 3.83Å; F132-V141 HydrophobicContact CD1-CG2 4.37Å; F132-V141 HydrophobicContact CE1-CB 4.16Å; F132-V141 HydrophobicContact CE1-CG1 4.23Å; F132-V141 HydrophobicContact CE1-CG2 3.61Å; F132-V141 HydrophobicContact CZ-CB 4.06Å; F132-V141 HydrophobicContact CZ-CG1 3.9Å; F132-V141 HydrophobicContact CZ-CG2 4.04Å; Q137-V141 VanDerWaalsContact O-CG2 3.27Å; Q137-V141 WeakPolarHBondContact O-CG2 3.36Å; Q137-V141 PolarHBondContact O-N 2.93Å; F138-V141 PolarHBondContact O-N 2.83Å; V141-R143 VanDerWaalsContact C-N 3.27Å; V141-R143 PolarHBondContact O-N 3.3Å; V141-Y144 PolarHBondContact O-N 3.33Å; V141-L145 HydrophobicContact CG1-CD1 3.73Å; V141-L145 HydrophobicContact CG1-CG 4.12Å; V141-L145 WeakPolarHBondContact O-CB 3.33Å; V141-L145 VanDerWaalsContact O-CG 3.29Å; V141-L145 WeakPolarHBondContact O-CG 3.46Å; V141-L145 PolarHBondContact O-N 3.47Å; V141-L154 HydrophobicContact CG1-CD2 4.16Å; V141-M156 HydrophobicContact CG2-CE 3.44Å; V141-M156 VanDerWaalsContact CG2-CE 3.44Å; V141-M156 HydrophobicContact CG2-SD 3.84Å; V141-P161 HydrophobicContact CG2-CB 3.67Å; V141-P161 HydrophobicContact CG2-CG 3.86Å
142M98.6Very high98.5Very high0 Ų030 Ų300%014%0.138CC..Hα-helixtrans-60.8-37.3178.9-62.9-52.3-94.100112L7 M104 I107 M108 F138 S146L7-M142 HydrophobicContact CB-CB 4.04Å; L7-M142 HydrophobicContact CB-CG 4.46Å; L7-M142 HydrophobicContact CD1-CE 3.69Å; L7-M142 WeakPolarHBondContact O-CB 3.22Å; M104-M142 HydrophobicContact CB-CE 3.87Å; M104-M142 HydrophobicContact CB-SD 4.32Å; M104-M142 HydrophobicContact CE-CB 4.07Å; M104-M142 HydrophobicContact CE-CE 3.37Å; M104-M142 HydrophobicContact CE-CG 4.49Å; M104-M142 HydrophobicContact CE-SD 4.01Å; M104-M142 HydrophobicContact CG-CE 3.92Å; M104-M142 HydrophobicContact CG-SD 3.88Å; M104-M142 HydrophobicContact SD-CE 4.46Å; I107-M142 HydrophobicContact CG2-SD 4.26Å; M108-M142 HydrophobicContact CG-CE 3.59Å; M108-M142 HydrophobicContact SD-CE 3.72Å; F138-M142 HydrophobicContact CD1-CG 4.27Å; F138-M142 HydrophobicContact CD2-CG 4.33Å; F138-M142 HydrophobicContact CE1-CG 3.83Å; F138-M142 HydrophobicContact CE2-CE 4.33Å; F138-M142 HydrophobicContact CE2-CG 3.9Å; F138-M142 HydrophobicContact CE2-SD 4.1Å; F138-M142 HydrophobicContact CG-CG 4.48Å; F138-M142 HydrophobicContact CZ-CE 4.08Å; F138-M142 HydrophobicContact CZ-CG 3.61Å; F138-M142 HydrophobicContact CZ-SD 4.2Å; F138-M142 VanDerWaalsContact O-CG 3.28Å; F138-M142 WeakPolarHBondContact O-CG 3.49Å; F138-M142 PolarHBondContact O-N 3.45Å; M142-S146 WeakPolarHBondContact O-CB 3.46Å; M142-S146 PolarHBondContact O-N 3.35Å; M142-S146 VanDerWaalsContact O-N 3.14Å
143R98.6Very high98.5Very high103 Ų10330.4 Ų30.439%0.38914%0.141SC..Hα-helixtrans-62.3-55.4171.1172.3173.2172-176.5-2.8111.9C8 R139 L140 V141 L145 S146 E147C8-R143 WeakPolarHBondContact O-CB 3.46Å; C8-R143 WeakPolarHBondContact O-CG 3.31Å; R139-R143 PolarHBondContact O-N 3.21Å; R139-R143 VanDerWaalsContact O-N 3.12Å; L140-R143 WeakPolarHBondContact O-CB 3.47Å; L140-R143 PolarHBondContact O-N 2.95Å; V141-R143 VanDerWaalsContact C-N 3.27Å; V141-R143 PolarHBondContact O-N 3.3Å; R143-L145 VanDerWaalsContact C-N 3.31Å; R143-L145 PolarHBondContact O-N 3.47Å; R143-S146 PolarHBondContact O-N 3.47Å; R143-S146 PolarHBondContact O-OG 3.04Å; R143-E147 IonicContact NE-OE2 3.05Å; R143-E147 PolarHBondContact O-N 2.93Å
144Y98.9Very high98.5Very high55 Ų5530.5 Ų30.522%0.21614%0.141CC..Hα-helixtrans-59.1-42.2-177.6-71.2-47000112.2L140 V141 S146 E147 M148 L154 P161 L164L140-Y144 HydrophobicContact CB-CE2 4.26Å; L140-Y144 WeakPolarHBondContact O-CD2 3.32Å; L140-Y144 PolarHBondContact O-N 2.97Å; V141-Y144 PolarHBondContact O-N 3.33Å; Y144-S146 VanDerWaalsContact C-N 3.29Å; Y144-S146 PolarHBondContact O-N 2.97Å; Y144-E147 PolarHBondContact O-N 3.37Å; Y144-M148 VanDerWaalsContact O-CB 3.28Å; Y144-M148 WeakPolarHBondContact O-CB 3.38Å; Y144-M148 PolarHBondContact O-N 3.36Å; Y144-L154 HydrophobicContact CD2-CD1 3.91Å; Y144-L154 HydrophobicContact CG-CD1 4.21Å; Y144-P161 HydrophobicContact CD2-CB 3.81Å; Y144-P161 HydrophobicContact CD2-CG 4.37Å; Y144-P161 HydrophobicContact CE2-CB 3.86Å; Y144-P161 HydrophobicContact CE2-CG 4.17Å; Y144-L164 HydrophobicContact CD1-CD1 4.07Å; Y144-L164 HydrophobicContact CD1-CG 4Å; Y144-L164 HydrophobicContact CG-CG 4.26Å
145L98.8Very high98.5Very high2 Ų231.8 Ų31.81%0.0115%0.149CC..Hα-helixtrans-62.6-34.4175.3-69.8-179.7000112.6A100 M103 M104 I107 V141 R143 M148 L154A100-L145 HydrophobicContact CB-CB 4.3Å; A100-L145 HydrophobicContact CB-CD2 4.26Å; A100-L145 WeakPolarHBondContact CB-O 3.34Å; M103-L145 HydrophobicContact CB-CD1 4.07Å; M103-L145 HydrophobicContact CB-CD2 4.43Å; M103-L145 HydrophobicContact CE-CD2 3.41Å; M103-L145 VanDerWaalsContact CE-CD2 3.41Å; M103-L145 HydrophobicContact SD-CD2 4.38Å; M104-L145 HydrophobicContact CG-CB 3.73Å; M104-L145 HydrophobicContact CG-CD1 3.65Å; M104-L145 HydrophobicContact CG-CG 4.36Å; M104-L145 HydrophobicContact SD-CB 3.98Å; I107-L145 HydrophobicContact CD1-CD1 3.65Å; V141-L145 HydrophobicContact CG1-CD1 3.73Å; V141-L145 HydrophobicContact CG1-CG 4.12Å; V141-L145 WeakPolarHBondContact O-CB 3.33Å; V141-L145 VanDerWaalsContact O-CG 3.29Å; V141-L145 WeakPolarHBondContact O-CG 3.46Å; V141-L145 PolarHBondContact O-N 3.47Å; R143-L145 VanDerWaalsContact C-N 3.31Å; R143-L145 PolarHBondContact O-N 3.47Å; L145-M148 HydrophobicContact CD2-SD 3.79Å; L145-L154 HydrophobicContact CD2-CD2 3.97Å; L145-L154 HydrophobicContact CG-CD2 4.19Å
146S98.4Very high98.6Very high12 Ų1231.6 Ų31.68%0.08415%0.148CC..Hα-helixtrans-70-36178.4730000113.6C8 C95 R96 M142 R143 Y144C8-S146 WeakPolarHBondContact CB-OG 3.39Å; C8-S146 WeakPolarHBondContact SG-CB 3.46Å; C95-S146 WeakPolarHBondContact CA-O 3.24Å; R96-S146 PolarHBondContact N-O 3.26Å; R96-S146 VanDerWaalsContact N-O 3.11Å; M142-S146 WeakPolarHBondContact O-CB 3.46Å; M142-S146 PolarHBondContact O-N 3.35Å; M142-S146 VanDerWaalsContact O-N 3.14Å; R143-S146 PolarHBondContact O-N 3.47Å; R143-S146 PolarHBondContact O-OG 3.04Å; Y144-S146 VanDerWaalsContact C-N 3.29Å; Y144-S146 PolarHBondContact O-N 2.97Å
147E98Very high98.6Very high64 Ų6437.6 Ų37.630%0.29917%0.172SC..Hα-helixtrans-98.7-14.3-173.571.2-174.3-164.200114.6R96 R143 Y144 L164R96-E147 VanDerWaalsContact CD-O 3.26Å; R96-E147 WeakPolarHBondContact CD-O 3.45Å; R96-E147 PolarHBondContact NE-O 3.4Å; R96-E147 PolarHBondContact NH1-O 2.78Å; R96-E147 VanDerWaalsContact NH1-O 3.12Å; R143-E147 IonicContact NE-OE2 3.05Å; R143-E147 PolarHBondContact O-N 2.93Å; Y144-E147 PolarHBondContact O-N 3.37Å; E147-L164 HydrophobicContact CG-CD1 4.15Å
148M98.6Very high98.6Very high0 Ų038.1 Ų38.10%018%0.175CC..  trans-65.3148.2-17772.1175.5-54.600113R96 A100 M103 Y144 L145 Q152 L164 R173R96-M148 WeakPolarHBondContact CB-O 3.2Å; A100-M148 HydrophobicContact CB-CG 3.86Å; A100-M148 HydrophobicContact CB-SD 3.8Å; M103-M148 HydrophobicContact CE-SD 4.36Å; Y144-M148 VanDerWaalsContact O-CB 3.28Å; Y144-M148 WeakPolarHBondContact O-CB 3.38Å; Y144-M148 PolarHBondContact O-N 3.36Å; L145-M148 HydrophobicContact CD2-SD 3.79Å; M148-Q152 HydrophobicContact CE-CB 4.32Å; M148-Q152 WeakPolarHBondContact CE-O 3.43Å; M148-L164 HydrophobicContact CB-CD1 3.72Å; M148-L164 HydrophobicContact CB-CD2 3.65Å; M148-L164 HydrophobicContact CB-CG 4.34Å; M148-L164 HydrophobicContact CE-CD2 4.25Å; M148-L164 HydrophobicContact SD-CD2 4.43Å; M148-R173 HydrophobicContact CE-CB 3.8Å; M148-R173 HydrophobicContact CE-CG 4.28Å; M148-R173 WeakPolarHBondContact CE-O 3.22Å; M148-R173 HydrophobicContact SD-CB 4.21Å
149T98.5Very high98.5Very high47 Ų4738.1 Ų38.129%0.28818%0.175SC..  trans-100.2175.7174.664.30000111.3E151 Q152T149-E151 PolarHBondContact O-N 3.14Å; T149-E151 PolarHBondContact OG1-N 3.47Å; T149-Q152 PolarHBondContact O-N 2.93Å; T149-Q152 PolarHBondContact OG1-OE1 3.42Å
150E96.8Very high98.5Very high112 Ų11239.7 Ų39.752%0.52318%0.184SC..THydrogen-bonded Turntrans-68.7-16.3174.2-60.9-173.7168.200112.7T97 Q152 P169 R173T97-E150 HydrophobicContact CG2-CG 3.67Å; E150-Q152 VanDerWaalsContact C-N 3.27Å; E150-Q152 PolarHBondContact O-N 2.97Å; E150-P169 VanDerWaalsContact O-CA 3.32Å; E150-P169 WeakPolarHBondContact O-CA 3.41Å; E150-R173 PolarHBondContact O-NH1 2.9Å; E150-R173 PolarHBondContact O-NH2 3.23Å
151E98.1Very high98.5Very high128 Ų12838.6 Ų38.660%0.59818%0.178SC*.THydrogen-bonded Turntrans-9623.1178.3-60.7-177.8165.600111.9T149 P166 S167 P169T149-E151 PolarHBondContact O-N 3.14Å; T149-E151 PolarHBondContact OG1-N 3.47Å; E151-P166 CarbonylContact O-C 3.53Å; E151-P166 WeakPolarHBondContact O-CA 3.45Å; E151-S167 CarbonylContact C-O 3.21Å; E151-S167 VanDerWaalsContact CA-O 3.31Å; E151-S167 WeakPolarHBondContact CA-O 3.4Å; E151-S167 PolarHBondContact O-N 3.29Å; E151-P169 HydrophobicContact CG-CG 4.33Å
152Q98.8Very high98.5Very high47 Ų4742.6 Ų42.622%0.2220%0.198CC..EExtended strand (participates in β ladder)trans-133.9152.2-179.9-68.2173.9-64.300111.9M148 T149 E150 L164 F165 S167 R173M148-Q152 HydrophobicContact CE-CB 4.32Å; M148-Q152 WeakPolarHBondContact CE-O 3.43Å; T149-Q152 PolarHBondContact O-N 2.93Å; T149-Q152 PolarHBondContact OG1-OE1 3.42Å; E150-Q152 VanDerWaalsContact C-N 3.27Å; E150-Q152 PolarHBondContact O-N 2.97Å; Q152-L164 HydrophobicContact CB-CB 4.47Å; Q152-F165 CarbonylContact C-O 3.36Å; Q152-F165 VanDerWaalsContact CA-O 3.27Å; Q152-F165 WeakPolarHBondContact CA-O 3.23Å; Q152-S167 PolarHBondContact O-OG 2.89Å; Q152-R173 PolarHBondContact O-NE 2.8Å
153T98.9Very high98.5Very high8 Ų843 Ų435%0.04920%0.202CC..EExtended strand (participates in β ladder)trans-128.3127.3172.7-630000109.2F165 S167 P172 I175T153-F165 PolarHBondContact N-O 3.38Å; T153-F165 PolarHBondContact O-N 2.92Å; T153-S167 PolarHBondContact N-OG 2.87Å; T153-S167 VanDerWaalsContact OG1-CB 3.23Å; T153-S167 WeakPolarHBondContact OG1-CB 3.33Å; T153-S167 PolarHBondContact OG1-OG 3.04Å; T153-P172 WeakPolarHBondContact CB-O 3.31Å; T153-P172 VanDerWaalsContact CG2-O 3.27Å; T153-P172 WeakPolarHBondContact CG2-O 3.23Å; T153-P172 PolarHBondContact OG1-O 3.36Å; T153-I175 HydrophobicContact CG2-CB 4.44Å; T153-I175 HydrophobicContact CG2-CD1 3.86Å; T153-I175 HydrophobicContact CG2-CG1 3.76Å
154L98.9Very high98.5Very high2 Ų239.8 Ų39.81%0.0119%0.192CC..EExtended strand (participates in β ladder)trans-77.9121.5169.8178.159000109.9V141 Y144 L145 M156 P161 L164 R173 A174 I175V141-L154 HydrophobicContact CG1-CD2 4.16Å; Y144-L154 HydrophobicContact CD2-CD1 3.91Å; Y144-L154 HydrophobicContact CG-CD1 4.21Å; L145-L154 HydrophobicContact CD2-CD2 3.97Å; L145-L154 HydrophobicContact CG-CD2 4.19Å; L154-M156 HydrophobicContact CD1-SD 4.05Å; L154-M156 HydrophobicContact CD2-CG 4.43Å; L154-M156 HydrophobicContact CD2-SD 3.69Å; L154-M156 HydrophobicContact CG-CG 4.17Å; L154-M156 HydrophobicContact CG-SD 3.64Å; L154-P161 HydrophobicContact CD1-CB 4.11Å; L154-L164 HydrophobicContact CB-CD2 3.87Å; L154-L164 HydrophobicContact CD1-CD2 4.24Å; L154-R173 PolarHBondContact N-O 2.66Å; L154-A174 HydrophobicContact CB-CB 4.33Å; L154-A174 VanDerWaalsContact O-CA 3.25Å; L154-A174 WeakPolarHBondContact O-CA 3.23Å; L154-I175 PolarHBondContact O-N 3.43Å
155V98.8Very high98.5Very high31 Ų3141.9 Ų41.919%0.18820%0.203CC..EExtended strand (participates in β ladder)trans-98.4122178.4-173.70000110.2Y157 M162 G163 F165V155-Y157 HydrophobicContact CG1-CD1 3.93Å; V155-Y157 HydrophobicContact CG1-CE1 3.41Å; V155-Y157 VanDerWaalsContact CG1-CE1 3.41Å; V155-M162 HydrophobicContact CB-CB 4.35Å; V155-M162 WeakPolarHBondContact O-CB 3.2Å; V155-M162 PolarHBondContact O-N 3.06Å; V155-G163 PolarHBondContact N-O 3.39Å; V155-F165 HydrophobicContact CB-CD2 4.1Å; V155-F165 HydrophobicContact CB-CE2 4.1Å; V155-F165 HydrophobicContact CG2-CD2 3.51Å; V155-F165 HydrophobicContact CG2-CE2 3.97Å; V155-F165 HydrophobicContact CG2-CG 4.26Å
156M98.9Very high98.5Very high2 Ų247.4 Ų47.41%0.0124%0.239CC..EExtended strand (participates in β ladder)trans-112.7122-174.2-60.3-60.9-59.500111.8F132 V141 L154 G159 H160 P161 I175 I176 T177F132-M156 HydrophobicContact CD1-CE 4.33Å; F132-M156 HydrophobicContact CE1-CE 3.86Å; V141-M156 HydrophobicContact CG2-CE 3.44Å; V141-M156 VanDerWaalsContact CG2-CE 3.44Å; V141-M156 HydrophobicContact CG2-SD 3.84Å; L154-M156 HydrophobicContact CD1-SD 4.05Å; L154-M156 HydrophobicContact CD2-CG 4.43Å; L154-M156 HydrophobicContact CD2-SD 3.69Å; L154-M156 HydrophobicContact CG-CG 4.17Å; L154-M156 HydrophobicContact CG-SD 3.64Å; M156-G159 WeakPolarHBondContact CE-O 3.48Å; M156-H160 WeakPolarHBondContact CA-O 3.3Å; M156-P161 HydrophobicContact CE-CB 4.19Å; M156-P161 HydrophobicContact SD-CB 3.79Å; M156-I175 PolarHBondContact N-O 2.94Å; M156-I176 HydrophobicContact CB-CB 4.36Å; M156-I176 HydrophobicContact CB-CG1 4.17Å; M156-I176 HydrophobicContact CB-CG2 4.28Å; M156-I176 HydrophobicContact CG-CG1 4.16Å; M156-T177 PolarHBondContact O-N 3.01Å; M156-T177 VanDerWaalsContact O-N 3.09Å; M156-T177 PolarHBondContact O-OG1 2.88Å; M156-T177 VanDerWaalsContact O-OG1 3.07Å
157Y98.8Very high98.5Very high126 Ų12648.3 Ų48.349%0.49425%0.245SC..EExtended strand (participates in β ladder)trans-111.592.7178.8-7973.6000110.5V155 G159 H160 M162V155-Y157 HydrophobicContact CG1-CD1 3.93Å; V155-Y157 HydrophobicContact CG1-CE1 3.41Å; V155-Y157 VanDerWaalsContact CG1-CE1 3.41Å; Y157-G159 VanDerWaalsContact C-N 3.35Å; Y157-G159 PolarHBondContact O-N 3.08Å; Y157-H160 PolarHBondContact N-O 3.02Å; Y157-H160 VanDerWaalsContact O-CB 3.24Å; Y157-H160 WeakPolarHBondContact O-CB 3.22Å; Y157-H160 PolarHBondContact O-N 3.22Å; Y157-M162 HydrophobicContact CD1-CB 3.77Å; Y157-M162 HydrophobicContact CD1-CE 3.84Å; Y157-M162 HydrophobicContact CD1-CG 4.33Å; Y157-M162 HydrophobicContact CD2-CE 4.45Å; Y157-M162 HydrophobicContact CE1-CB 3.95Å; Y157-M162 HydrophobicContact CE1-CE 3.94Å; Y157-M162 HydrophobicContact CE1-CG 4.1Å; Y157-M162 HydrophobicContact CG-CE 4.1Å
158S98.4Very high98.4Very high11 Ų1150.6 Ų50.68%0.07726%0.259CS..THydrogen-bonded Turntrans47.356.9-179.8-61.50000112.3H160 T177 N178 G179 M201S158-H160 PolarHBondContact O-N 3.31Å; S158-T177 VanDerWaalsContact CA-O 3.24Å; S158-T177 WeakPolarHBondContact CA-O 3.48Å; S158-T177 PolarHBondContact N-O 3.02Å; S158-N178 WeakPolarHBondContact CA-OD1 3.5Å; S158-G179 PolarHBondContact OG-N 2.88Å; S158-M201 VanDerWaalsContact C-CG 3.46Å; S158-M201 VanDerWaalsContact C-SD 3.58Å; S158-M201 WeakPolarHBondContact O-CG 3.38Å
159G98.3Very high98.3Very high0 Ų053.1 Ų53.10%028%0.275CS..THydrogen-bonded Turntrans81.9-24.9-174.900000115.2F132 Q137 M156 Y157 P161 N178F132-G159 WeakPolarHBondContact CD1-O 3.47Å; Q137-G159 WeakPolarHBondContact CB-O 3.49Å; Q137-G159 VanDerWaalsContact CD-C 3.42Å; Q137-G159 PolarHBondContact OE1-O 2.93Å; M156-G159 WeakPolarHBondContact CE-O 3.48Å; Y157-G159 VanDerWaalsContact C-N 3.35Å; Y157-G159 PolarHBondContact O-N 3.08Å; G159-P161 VanDerWaalsContact O-CD 3.3Å; G159-P161 WeakPolarHBondContact O-CD 3.37Å; G159-N178 PolarHBondContact N-OD1 3.38Å
160H98.8Very high98Very high56 Ų5653.7 Ų53.726%0.25928%0.281SS..EExtended strand (participates in β ladder)trans-71.6120.7177.5174.968.6000111.6Y51 M156 Y157 S158 M162Y51-H160 AromaticContact CE1-CE1 3.9Å; Y51-H160 AromaticContact CE1-ND1 3.41Å; Y51-H160 WeakPolarHBondContact CE1-ND1 3.48Å; Y51-H160 AromaticContact CZ-ND1 3.57Å; Y51-H160 PolarHBondContact OH-ND1 3.34Å; M156-H160 WeakPolarHBondContact CA-O 3.3Å; Y157-H160 PolarHBondContact N-O 3.02Å; Y157-H160 VanDerWaalsContact O-CB 3.24Å; Y157-H160 WeakPolarHBondContact O-CB 3.22Å; Y157-H160 PolarHBondContact O-N 3.22Å; S158-H160 PolarHBondContact O-N 3.31Å; H160-M162 PolarHBondContact O-N 3.03Å
161P98.6Very high98.1Very high3 Ų349.8 Ų49.82%0.01927%0.266CS..EExtended strand (participates in β ladder)trans-78.910017330.9-32.1000110.3L140 V141 Y144 L154 M156 G159 G163L140-P161 HydrophobicContact CB-CG 3.59Å; L140-P161 HydrophobicContact CD1-CG 4.3Å; V141-P161 HydrophobicContact CG2-CB 3.67Å; V141-P161 HydrophobicContact CG2-CG 3.86Å; Y144-P161 HydrophobicContact CD2-CB 3.81Å; Y144-P161 HydrophobicContact CD2-CG 4.37Å; Y144-P161 HydrophobicContact CE2-CB 3.86Å; Y144-P161 HydrophobicContact CE2-CG 4.17Å; L154-P161 HydrophobicContact CD1-CB 4.11Å; M156-P161 HydrophobicContact CE-CB 4.19Å; M156-P161 HydrophobicContact SD-CB 3.79Å; G159-P161 VanDerWaalsContact O-CD 3.3Å; G159-P161 WeakPolarHBondContact O-CD 3.37Å; P161-G163 VanDerWaalsContact C-N 3.25Å; P161-G163 PolarHBondContact O-N 3.46Å
162M98.6Very high98.1Very high86 Ų8644 Ų4442%0.42424%0.24SC..EExtended strand (participates in β ladder)trans-62-37.9179.6-173.360.267.900111.4V155 Y157 H160 F165V155-M162 HydrophobicContact CB-CB 4.35Å; V155-M162 WeakPolarHBondContact O-CB 3.2Å; V155-M162 PolarHBondContact O-N 3.06Å; Y157-M162 HydrophobicContact CD1-CB 3.77Å; Y157-M162 HydrophobicContact CD1-CE 3.84Å; Y157-M162 HydrophobicContact CD1-CG 4.33Å; Y157-M162 HydrophobicContact CD2-CE 4.45Å; Y157-M162 HydrophobicContact CE1-CB 3.95Å; Y157-M162 HydrophobicContact CE1-CE 3.94Å; Y157-M162 HydrophobicContact CE1-CG 4.1Å; Y157-M162 HydrophobicContact CG-CE 4.1Å; H160-M162 PolarHBondContact O-N 3.03Å; M162-F165 HydrophobicContact CB-CE2 4.4Å; M162-F165 HydrophobicContact CG-CE2 4.04Å; M162-F165 HydrophobicContact CG-CZ 4.06Å
163G98.6Very high98.1Very high8 Ų841.8 Ų41.88%0.08223%0.229CC..EExtended strand (participates in β ladder)trans148.1-178.7174.800000113V155 P161 F165V155-G163 PolarHBondContact N-O 3.39Å; P161-G163 VanDerWaalsContact C-N 3.25Å; P161-G163 PolarHBondContact O-N 3.46Å; G163-F165 WeakPolarHBondContact O-CD2 3.24Å
164L98.9Very high98.1Very high35 Ų3541.5 Ų41.518%0.18323%0.228CC..EExtended strand (participates in β ladder)trans-90.6122.1173.5-63.4175.2000109.7Y144 E147 M148 Q152 L154Y144-L164 HydrophobicContact CD1-CD1 4.07Å; Y144-L164 HydrophobicContact CD1-CG 4Å; Y144-L164 HydrophobicContact CG-CG 4.26Å; E147-L164 HydrophobicContact CG-CD1 4.15Å; M148-L164 HydrophobicContact CB-CD1 3.72Å; M148-L164 HydrophobicContact CB-CD2 3.65Å; M148-L164 HydrophobicContact CB-CG 4.34Å; M148-L164 HydrophobicContact CE-CD2 4.25Å; M148-L164 HydrophobicContact SD-CD2 4.43Å; Q152-L164 HydrophobicContact CB-CB 4.47Å; L154-L164 HydrophobicContact CB-CD2 3.87Å; L154-L164 HydrophobicContact CD1-CD2 4.24Å
165F98.8Very high98.1Very high99 Ų9944.1 Ų44.143%0.43424%0.241SC..EExtended strand (participates in β ladder)trans-112.5143.9176.8-66.7-100.5000109.7Q152 T153 V155 M162 G163Q152-F165 CarbonylContact C-O 3.36Å; Q152-F165 VanDerWaalsContact CA-O 3.27Å; Q152-F165 WeakPolarHBondContact CA-O 3.23Å; T153-F165 PolarHBondContact N-O 3.38Å; T153-F165 PolarHBondContact O-N 2.92Å; V155-F165 HydrophobicContact CB-CD2 4.1Å; V155-F165 HydrophobicContact CB-CE2 4.1Å; V155-F165 HydrophobicContact CG2-CD2 3.51Å; V155-F165 HydrophobicContact CG2-CE2 3.97Å; V155-F165 HydrophobicContact CG2-CG 4.26Å; M162-F165 HydrophobicContact CB-CE2 4.4Å; M162-F165 HydrophobicContact CG-CE2 4.04Å; M162-F165 HydrophobicContact CG-CZ 4.06Å; G163-F165 WeakPolarHBondContact O-CD2 3.24Å
166P98.6Very high98.1Very high119 Ų11942.6 Ų42.677%0.77323%0.232SC*.EExtended strand (participates in β ladder)trans-57.4140.1175.3-24.534.4000112.4E151E151-P166 CarbonylContact O-C 3.53Å; E151-P166 WeakPolarHBondContact O-CA 3.45Å
167S97.9Very high98.1Very high30 Ų3044.1 Ų44.121%0.2124%0.241CC..  trans-154.9-175.6178.768.80000111.3E151 Q152 T153E151-S167 CarbonylContact C-O 3.21Å; E151-S167 VanDerWaalsContact CA-O 3.31Å; E151-S167 WeakPolarHBondContact CA-O 3.4Å; E151-S167 PolarHBondContact O-N 3.29Å; Q152-S167 PolarHBondContact O-OG 2.89Å; T153-S167 PolarHBondContact N-OG 2.87Å; T153-S167 VanDerWaalsContact OG1-CB 3.23Å; T153-S167 WeakPolarHBondContact OG1-CB 3.33Å; T153-S167 PolarHBondContact OG1-OG 3.04Å
168L96.9Very high98.1Very high112 Ų11238.1 Ų38.159%0.58622%0.218SC*.  trans-91.6154.8179-59174.5000110.6S170 S171 R173L168-S170 PolarHBondContact O-N 3.06Å; L168-S170 VanDerWaalsContact O-N 3.09Å; L168-S171 PolarHBondContact N-OG 2.91Å; L168-S171 WeakPolarHBondContact O-CB 3.5Å; L168-S171 PolarHBondContact O-N 2.85Å; L168-S171 PolarHBondContact O-OG 2.91Å; L168-R173 PolarHBondContact O-NH2 3.27Å
169P95.3Very high98.1Very high54 Ų5437.6 Ų37.635%0.35121%0.214SC..THydrogen-bonded Turntrans-52.7-32.7172.6-29.837000114.3E150 E151 S171 R173E150-P169 VanDerWaalsContact O-CA 3.32Å; E150-P169 WeakPolarHBondContact O-CA 3.41Å; E151-P169 HydrophobicContact CG-CG 4.33Å; P169-S171 VanDerWaalsContact C-N 3.35Å; P169-R173 PolarHBondContact O-NH1 3.18Å
170S92.9Very high98.1Very high59 Ų5940.9 Ų40.941%0.41323%0.23SC..THydrogen-bonded Turntrans-79.1-12.3176.660.10000114.6L168L168-S170 PolarHBondContact O-N 3.06Å; L168-S170 VanDerWaalsContact O-N 3.09Å
171S97.6Very high98Very high30 Ų3039.9 Ų39.921%0.2123%0.228CC..SBendtrans-71161.6176.7-59.80000111.5L168 P169 R173L168-S171 PolarHBondContact N-OG 2.91Å; L168-S171 WeakPolarHBondContact O-CB 3.5Å; L168-S171 PolarHBondContact O-N 2.85Å; L168-S171 PolarHBondContact O-OG 2.91Å; P169-S171 VanDerWaalsContact C-N 3.35Å; S171-R173 VanDerWaalsContact O-CZ 3.26Å; S171-R173 PolarHBondContact O-NH1 3.22Å; S171-R173 PolarHBondContact O-NH2 2.93Å
172P98.6Very high98Very high6 Ų645.4 Ų45.44%0.03926%0.256CS..  trans-65142.4172.4-18.933.6000110.6T153 A174 I175 A579 A583 T584 V586T153-P172 WeakPolarHBondContact CB-O 3.31Å; T153-P172 VanDerWaalsContact CG2-O 3.27Å; T153-P172 WeakPolarHBondContact CG2-O 3.23Å; T153-P172 PolarHBondContact OG1-O 3.36Å; P172-A174 VanDerWaalsContact C-N 3.26Å; P172-A174 WeakPolarHBondContact CB-O 3.25Å; P172-I175 HydrophobicContact CB-CG1 4.45Å; P172-A579 WeakPolarHBondContact CD-O 3.41Å; P172-A579 HydrophobicContact CG-CB 4.02Å; P172-A579 VanDerWaalsContact CG-O 3.29Å; P172-A579 WeakPolarHBondContact CG-O 3.35Å; P172-A583 WeakPolarHBondContact CA-O 3.27Å; P172-T584 CarbonylContact C-O 3.5Å; P172-T584 WeakPolarHBondContact CA-O 3.28Å; P172-V586 HydrophobicContact CG-CG2 4.39Å
173R98.8Very high97.9Very high1 Ų146.5 Ų46.50%0.00427%0.27CS..SBendtrans-72.1-22.5171.8-63.1-66.578.986.11.6112.2Q99 M103 M148 E150 Q152 L154 L168 P169 S171 T584Q99-R173 HydrophobicContact CB-CG 3.66Å; Q99-R173 HydrophobicContact CG-CG 4.42Å; M103-R173 HydrophobicContact CE-CB 3.33Å; M103-R173 HydrophobicContact CE-CG 4.36Å; M103-R173 HydrophobicContact SD-CB 4.36Å; M148-R173 HydrophobicContact CE-CB 3.8Å; M148-R173 HydrophobicContact CE-CG 4.28Å; M148-R173 WeakPolarHBondContact CE-O 3.22Å; M148-R173 HydrophobicContact SD-CB 4.21Å; E150-R173 PolarHBondContact O-NH1 2.9Å; E150-R173 PolarHBondContact O-NH2 3.23Å; Q152-R173 PolarHBondContact O-NE 2.8Å; L154-R173 PolarHBondContact N-O 2.66Å; L168-R173 PolarHBondContact O-NH2 3.27Å; P169-R173 PolarHBondContact O-NH1 3.18Å; S171-R173 VanDerWaalsContact O-CZ 3.26Å; S171-R173 PolarHBondContact O-NH1 3.22Å; S171-R173 PolarHBondContact O-NH2 2.93Å; R173-T584 HydrophobicContact CG-CG2 4.4Å; R173-T584 PolarHBondContact N-O 3.46Å
174A98.8Very high97.8Very high2 Ų253.4 Ų53.42%0.01731%0.305CS..EExtended strand (participates in β ladder)trans-141144.1169.600000112.7M103 L154 P172 I176 W585 V586M103-A174 HydrophobicContact CE-CB 4.37Å; M103-A174 HydrophobicContact SD-CB 3.72Å; L154-A174 HydrophobicContact CB-CB 4.33Å; L154-A174 VanDerWaalsContact O-CA 3.25Å; L154-A174 WeakPolarHBondContact O-CA 3.23Å; P172-A174 VanDerWaalsContact C-N 3.26Å; P172-A174 WeakPolarHBondContact CB-O 3.25Å; A174-I176 HydrophobicContact CB-CG1 4.45Å; A174-W585 HydrophobicContact CB-CB 3.99Å; A174-W585 VanDerWaalsContact O-CA 3.27Å; A174-W585 WeakPolarHBondContact O-CA 3.27Å; A174-W585 WeakPolarHBondContact O-CB 3.37Å; A174-V586 PolarHBondContact O-N 3.34Å
175I98.8Very high97.7Very high56 Ų5658.6 Ų58.629%0.28732%0.323SS..EExtended strand (participates in β ladder)trans-119.6122169.9-62.3172.4000107.7T153 L154 M156 P172 F575 V586T153-I175 HydrophobicContact CG2-CB 4.44Å; T153-I175 HydrophobicContact CG2-CD1 3.86Å; T153-I175 HydrophobicContact CG2-CG1 3.76Å; L154-I175 PolarHBondContact O-N 3.43Å; M156-I175 PolarHBondContact N-O 2.94Å; P172-I175 HydrophobicContact CB-CG1 4.45Å; I175-F575 HydrophobicContact CG2-CE2 4.18Å; I175-F575 HydrophobicContact CG2-CZ 3.57Å; I175-V586 HydrophobicContact CB-CG2 4.48Å; I175-V586 HydrophobicContact CG1-CG2 4.15Å; I175-V586 HydrophobicContact CG2-CG2 4.29Å
176I98.9Very high97.6Very high0 Ų054.7 Ų54.70%031%0.308CS..EExtended strand (participates in β ladder)trans-117.3128.4-169.5-51.8164.8000110.9M156 A174 N178 Y210 V586 A587 L588M156-I176 HydrophobicContact CB-CB 4.36Å; M156-I176 HydrophobicContact CB-CG1 4.17Å; M156-I176 HydrophobicContact CB-CG2 4.28Å; M156-I176 HydrophobicContact CG-CG1 4.16Å; A174-I176 HydrophobicContact CB-CG1 4.45Å; I176-N178 WeakPolarHBondContact CG2-ND2 3.04Å; I176-Y210 HydrophobicContact CD1-CD2 3.74Å; I176-Y210 HydrophobicContact CD1-CE2 3.39Å; I176-Y210 HydrophobicContact CG1-CE2 4.25Å; I176-V586 WeakPolarHBondContact CB-O 3.21Å; I176-V586 PolarHBondContact N-O 3.01Å; I176-A587 HydrophobicContact CB-CB 3.96Å; I176-A587 HydrophobicContact CD1-CB 4.46Å; I176-A587 HydrophobicContact CG2-CB 4.37Å; I176-A587 CarbonylContact O-C 3.21Å; I176-A587 VanDerWaalsContact O-CA 3.26Å; I176-A587 WeakPolarHBondContact O-CA 3.33Å; I176-L588 PolarHBondContact O-N 2.76Å
177T98.9Very high97.5Very high34 Ų3451.6 Ų51.621%0.20929%0.289CS..EExtended strand (participates in β ladder)trans-121.3135.5165.556.80000109.2M156 S158 M180 L588M156-T177 PolarHBondContact O-N 3.01Å; M156-T177 VanDerWaalsContact O-N 3.09Å; M156-T177 PolarHBondContact O-OG1 2.88Å; M156-T177 VanDerWaalsContact O-OG1 3.07Å; S158-T177 VanDerWaalsContact CA-O 3.24Å; S158-T177 WeakPolarHBondContact CA-O 3.48Å; S158-T177 PolarHBondContact N-O 3.02Å; T177-M180 HydrophobicContact CG2-CG 4.16Å; T177-L588 VanDerWaalsContact CA-O 3.3Å; T177-L588 WeakPolarHBondContact CA-O 3.28Å
178N98.8Very high97.1Very high0 Ų053.2 Ų53.20%029%0.291CS..EExtended strand (participates in β ladder)trans-132.5121.5173.8-69.5-58.6000110.3S158 G159 I176 M180 G208 L588 H589 N590S158-N178 WeakPolarHBondContact CA-OD1 3.5Å; G159-N178 PolarHBondContact N-OD1 3.38Å; I176-N178 WeakPolarHBondContact CG2-ND2 3.04Å; N178-M180 VanDerWaalsContact C-N 3.3Å; N178-M180 PolarHBondContact O-N 2.93Å; N178-G208 WeakPolarHBondContact ND2-CA 3.11Å; N178-G208 PolarHBondContact ND2-O 2.76Å; N178-G208 VanDerWaalsContact ND2-O 3.08Å; N178-L588 PolarHBondContact N-O 3.24Å; N178-H589 PolarHBondContact ND2-CD2 2.86Å; N178-H589 PolarHBondContact ND2-NE2 3.24Å; N178-H589 CarbonylContact O-C 3.39Å; N178-H589 VanDerWaalsContact O-CA 3.28Å; N178-H589 WeakPolarHBondContact O-CA 3.35Å; N178-N590 PolarHBondContact O-N 2.73Å
179G97.9Very high96.8Very high0 Ų053.3 Ų53.30%029%0.288CS..SBendtrans75.414.1175.400000115.5S158 V181 S200 M201 N590S158-G179 PolarHBondContact OG-N 2.88Å; G179-V181 WeakPolarHBondContact O-CG2 3.27Å; G179-V181 PolarHBondContact O-N 3.34Å; G179-S200 WeakPolarHBondContact CA-OG 3.22Å; G179-M201 PolarHBondContact N-O 3.38Å; G179-N590 WeakPolarHBondContact O-CB 3.5Å; G179-N590 PolarHBondContact O-ND2 3.35Å
180M98.4Very high96.8Very high69 Ų6953.7 Ų53.734%0.3429%0.285SS..  trans-64.9118175.7-67.7-60.9100.900110.1T177 N178 L588 H589 N590 I600T177-M180 HydrophobicContact CG2-CG 4.16Å; N178-M180 VanDerWaalsContact C-N 3.3Å; N178-M180 PolarHBondContact O-N 2.93Å; M180-L588 HydrophobicContact CE-CG 4.25Å; M180-L588 HydrophobicContact SD-CD2 3.86Å; M180-L588 HydrophobicContact SD-CG 4.03Å; M180-H589 WeakPolarHBondContact CE-O 2.97Å; M180-N590 HydrophobicContact CE-CB 3.62Å; M180-I600 HydrophobicContact CE-CD1 4.26Å
181V96.8Very high96.9Very high35 Ų3551.1 Ų51.121%0.21227%0.266CS..  trans-138.4146.9-174.6175.90000109.4G179 M194 W596G179-V181 WeakPolarHBondContact O-CG2 3.27Å; G179-V181 PolarHBondContact O-N 3.34Å; V181-M194 HydrophobicContact CG1-CE 4.09Å; V181-M194 HydrophobicContact CG1-SD 4.42Å; V181-M194 HydrophobicContact CG2-CE 3.75Å; V181-M194 HydrophobicContact CG2-SD 3.87Å; V181-W596 HydrophobicContact CG2-CH2 4.26Å; V181-W596 HydrophobicContact CG2-CZ2 3.7Å
182I98.1Very high96.6Very high119 Ų11951.2 Ų51.261%0.6126%0.264SS*.  trans-56.6126.3172.2-60-57.9000108.5N184 Y185I182-N184 VanDerWaalsContact C-N 3.31Å; I182-N184 PolarHBondContact O-N 3.48Å; I182-Y185 HydrophobicContact CB-CD2 3.94Å; I182-Y185 HydrophobicContact CG2-CD2 3.87Å; I182-Y185 HydrophobicContact CG2-CE2 4.22Å; I182-Y185 WeakPolarHBondContact O-CA 3.38Å; I182-Y185 PolarHBondContact O-N 2.95Å
183P96.9Very high96.5Very high108 Ų10853.8 Ų53.870%0.70127%0.273SS*.G310 helixtrans-48.5-45.2-164.4-33.535.8000115.4Y185 S186P183-Y185 PolarHBondContact O-N 3.39Å; P183-S186 WeakPolarHBondContact O-CB 3.48Å; P183-S186 PolarHBondContact O-N 2.81Å
184N97.6Very high96.4Very high154 Ų15455.1 Ų55.182%0.82428%0.279SS*.G310 helixtrans-64.4-10.5-179.8-69.4-8.6000114.8I182I182-N184 VanDerWaalsContact C-N 3.31Å; I182-N184 PolarHBondContact O-N 3.48Å
185Y97.1Very high96.3Very high143 Ų14355 Ų5556%0.56128%0.279SS*.G310 helixtrans-113.37.6178.7-58.4-87000112.4I182 P183 S187 Q190I182-Y185 HydrophobicContact CB-CD2 3.94Å; I182-Y185 HydrophobicContact CG2-CD2 3.87Å; I182-Y185 HydrophobicContact CG2-CE2 4.22Å; I182-Y185 WeakPolarHBondContact O-CA 3.38Å; I182-Y185 PolarHBondContact O-N 2.95Å; P183-Y185 PolarHBondContact O-N 3.39Å; Y185-S187 PolarHBondContact O-N 3.45Å; Y185-Q190 WeakPolarHBondContact O-CB 3.49Å
186S96.7Very high96.3Very high17 Ų1752.5 Ų52.512%0.11927%0.266CS..  trans-8734.8-177.9-167.90000113.3P183 N590 W596 G597P183-S186 WeakPolarHBondContact O-CB 3.48Å; P183-S186 PolarHBondContact O-N 2.81Å; S186-N590 PolarHBondContact OG-ND2 3.4Å; S186-W596 PolarHBondContact O-NE1 2.82Å; S186-W596 PolarHBondContact OG-NE1 3.29Å; S186-G597 WeakPolarHBondContact OG-CA 3.41Å
187S94.8Very high96.2Very high55 Ų5553.6 Ų53.639%0.38527%0.271SS..  trans-80.3159.3173.9830000111.6Y185 E189 Q190 Y191 W596Y185-S187 PolarHBondContact O-N 3.45Å; S187-E189 VanDerWaalsContact C-N 3.32Å; S187-E189 PolarHBondContact O-N 2.77Å; S187-Q190 PolarHBondContact O-N 3.16Å; S187-Q190 WeakPolarHBondContact OG-CG 3.31Å; S187-Q190 PolarHBondContact OG-N 3.28Å; S187-Y191 PolarHBondContact O-N 2.88Å; S187-W596 PolarHBondContact O-NE1 3.22Å
188R90.4Very high96.2Very high63 Ų6352.9 Ų52.924%0.23827%0.271CS..Hα-helixtrans-65.1-35.2179.2-60.9178.765.6-164.4-9.8112.5Y191 E192 H347 N348 E410 W596R188-Y191 WeakPolarHBondContact O-CB 3.26Å; R188-Y191 PolarHBondContact O-N 3.23Å; R188-E192 PolarHBondContact O-N 3.01Å; R188-E192 VanDerWaalsContact O-N 3.1Å; R188-H347 PolarHBondContact NH1-O 3.33Å; R188-H347 PolarHBondContact NH2-O 3.15Å; R188-N348 VanDerWaalsContact NH2-CA 3.3Å; R188-E410 IonicContact NH1-OE1 3.05Å; R188-W596 HydrophobicContact CG-CB 4.38Å
189E90.4Very high96.2Very high115 Ų11556.5 Ų56.554%0.53729%0.293SS..Hα-helixtrans-62.6-43.8172.7-175-169.4163.100111.3S187 Y191 E192 R193S187-E189 VanDerWaalsContact C-N 3.32Å; S187-E189 PolarHBondContact O-N 2.77Å; E189-Y191 VanDerWaalsContact C-N 3.32Å; E189-Y191 PolarHBondContact O-N 2.98Å; E189-E192 PolarHBondContact O-N 3.18Å; E189-R193 PolarHBondContact O-N 3.2Å; E189-R193 IonicContact OE1-CZ 3.87Å; E189-R193 IonicContact OE1-NH1 2.66Å; E189-R193 PolarHBondContact OE1-NH1 2.88Å; E189-R193 IonicContact OE1-NH2 3.12Å; E189-R193 PolarHBondContact OE1-NH2 3.48Å
190Q94.9Very high96.2Very high61 Ų6156.7 Ų56.729%0.28529%0.294SS..Hα-helixtrans-65.1-38176.7-68.7-64.1-19.700111.3Y185 S187 R193 M194Y185-Q190 WeakPolarHBondContact O-CB 3.49Å; S187-Q190 PolarHBondContact O-N 3.16Å; S187-Q190 WeakPolarHBondContact OG-CG 3.31Å; S187-Q190 PolarHBondContact OG-N 3.28Å; Q190-R193 PolarHBondContact O-N 3.41Å; Q190-M194 VanDerWaalsContact C-CE 3.48Å; Q190-M194 HydrophobicContact CB-CE 3.87Å; Q190-M194 WeakPolarHBondContact O-CB 3.48Å; Q190-M194 VanDerWaalsContact O-CE 3.31Å; Q190-M194 WeakPolarHBondContact O-CE 3.33Å; Q190-M194 WeakPolarHBondContact O-CG 3.23Å; Q190-M194 PolarHBondContact O-N 3.45Å
191Y94.8Very high96.1Very high5 Ų553.4 Ų53.42%0.0228%0.278CS..Hα-helixtrans-56.4-51.9172.1161.2-111.5000112.5R32 N128 S187 R188 E189 R193 M194 F195 Y202 W596R32-Y191 PolarHBondContact NH1-OH 3Å; R32-Y191 VanDerWaalsContact NH1-OH 3.11Å; R32-Y191 PolarHBondContact NH2-OH 3.17Å; N128-Y191 PolarHBondContact ND2-OH 3.42Å; S187-Y191 PolarHBondContact O-N 2.88Å; R188-Y191 WeakPolarHBondContact O-CB 3.26Å; R188-Y191 PolarHBondContact O-N 3.23Å; E189-Y191 VanDerWaalsContact C-N 3.32Å; E189-Y191 PolarHBondContact O-N 2.98Å; Y191-R193 PolarHBondContact O-N 3.41Å; Y191-M194 PolarHBondContact O-N 3Å; Y191-F195 HydrophobicContact CD2-CB 4.31Å; Y191-F195 HydrophobicContact CE2-CB 3.93Å; Y191-F195 HydrophobicContact CE2-CG 4.34Å; Y191-F195 VanDerWaalsContact O-CB 3.25Å; Y191-F195 WeakPolarHBondContact O-CB 3.41Å; Y191-F195 PolarHBondContact O-N 2.56Å; Y191-Y202 WeakPolarHBondContact OH-CB 3.47Å; Y191-W596 AromaticContact CD2-CD2 4Å; Y191-W596 HydrophobicContact CD2-CD2 4Å; Y191-W596 AromaticContact CD2-CE3 3.62Å; Y191-W596 HydrophobicContact CD2-CE3 3.62Å; Y191-W596 AromaticContact CD2-CH2 3.72Å; Y191-W596 HydrophobicContact CD2-CH2 3.72Å; Y191-W596 HydrophobicContact CD2-CZ2 4.13Å; Y191-W596 AromaticContact CD2-CZ3 3.48Å; Y191-W596 HydrophobicContact CD2-CZ3 3.48Å; Y191-W596 VanDerWaalsContact CD2-CZ3 3.48Å; Y191-W596 HydrophobicContact CE2-CE3 4.21Å; Y191-W596 HydrophobicContact CE2-CZ3 4.01Å; Y191-W596 AromaticContact CG-CD2 3.92Å; Y191-W596 HydrophobicContact CG-CD2 3.92Å; Y191-W596 AromaticContact CG-CE3 3.98Å; Y191-W596 HydrophobicContact CG-CE3 3.98Å; Y191-W596 HydrophobicContact CG-CG 4.3Å; Y191-W596 HydrophobicContact CG-CH2 4.45Å; Y191-W596 HydrophobicContact CG-CZ2 4.45Å; Y191-W596 HydrophobicContact CG-CZ3 4.26Å
192E92Very high96.2Very high32 Ų3251.9 Ų51.915%0.1527%0.269CS..Hα-helixtrans-59.9-38.5-178.5-65.2-60.315900111.3R32 R188 E189 A196R32-E192 IonicContact CZ-OE2 2.86Å; R32-E192 IonicContact NH1-OE1 3.06Å; R32-E192 PolarHBondContact NH1-OE1 3.35Å; R32-E192 IonicContact NH1-OE2 2.7Å; R32-E192 PolarHBondContact NH1-OE2 2.63Å; R188-E192 PolarHBondContact O-N 3.01Å; R188-E192 VanDerWaalsContact O-N 3.1Å; E189-E192 PolarHBondContact O-N 3.18Å; E192-A196 WeakPolarHBondContact O-CB 3.38Å; E192-A196 PolarHBondContact O-N 2.79Å; E192-A196 VanDerWaalsContact O-N 3.16Å
193R95.8Very high96.1Very high60 Ų6046.2 Ų46.223%0.22624%0.24CC..Hα-helixtrans-63.6-53.2172.4-71.1-176.4173.3129.88.6112.4L36 E189 Q190 Y191 F195 A196 L197L36-R193 HydrophobicContact CD2-CB 4.34Å; L36-R193 HydrophobicContact CD2-CG 4.23Å; E189-R193 PolarHBondContact O-N 3.2Å; E189-R193 IonicContact OE1-CZ 3.87Å; E189-R193 IonicContact OE1-NH1 2.66Å; E189-R193 PolarHBondContact OE1-NH1 2.88Å; E189-R193 IonicContact OE1-NH2 3.12Å; E189-R193 PolarHBondContact OE1-NH2 3.48Å; Q190-R193 PolarHBondContact O-N 3.41Å; Y191-R193 PolarHBondContact O-N 3.41Å; R193-F195 VanDerWaalsContact C-N 3.29Å; R193-F195 PolarHBondContact O-N 3.18Å; R193-A196 PolarHBondContact O-N 3.28Å; R193-L197 WeakPolarHBondContact O-CB 3.4Å; R193-L197 VanDerWaalsContact O-CG 3.25Å; R193-L197 WeakPolarHBondContact O-CG 3.21Å; R193-L197 PolarHBondContact O-N 3.11Å
194M97.6Very high96.1Very high30 Ų3041.4 Ų41.415%0.14821%0.208CC..Hα-helixtrans-61.9-36.8-178.1-78.1-174.9-74.400112.6V181 Q190 Y191 G198 V199 S200 W596V181-M194 HydrophobicContact CG1-CE 4.09Å; V181-M194 HydrophobicContact CG1-SD 4.42Å; V181-M194 HydrophobicContact CG2-CE 3.75Å; V181-M194 HydrophobicContact CG2-SD 3.87Å; Q190-M194 VanDerWaalsContact C-CE 3.48Å; Q190-M194 HydrophobicContact CB-CE 3.87Å; Q190-M194 WeakPolarHBondContact O-CB 3.48Å; Q190-M194 VanDerWaalsContact O-CE 3.31Å; Q190-M194 WeakPolarHBondContact O-CE 3.33Å; Q190-M194 WeakPolarHBondContact O-CG 3.23Å; Q190-M194 PolarHBondContact O-N 3.45Å; Y191-M194 PolarHBondContact O-N 3Å; M194-G198 PolarHBondContact O-N 3.2Å; M194-V199 HydrophobicContact CB-CG2 3.76Å; M194-V199 HydrophobicContact CG-CG2 3.89Å; M194-V199 VanDerWaalsContact O-CG2 3.27Å; M194-V199 WeakPolarHBondContact O-CG2 3.44Å; M194-V199 PolarHBondContact O-N 3.07Å; M194-S200 PolarHBondContact O-N 2.84Å; M194-W596 HydrophobicContact CE-CZ2 3.99Å
195F97.6Very high96.1Very high0 Ų034.2 Ų34.20%017%0.169CC..Hα-helixtrans-63.7-53175.8178.6-114.8000110.7R32 H73 Y75 Y191 R193 L197 G198 S200 M201R32-F195 VanDerWaalsContact CZ-CE1 3.45Å; H73-F195 HydrophobicContact CB-CE1 3.92Å; H73-F195 HydrophobicContact CB-CZ 4.41Å; H73-F195 AromaticContact CD2-CE1 3.88Å; H73-F195 AromaticContact CD2-CZ 3.49Å; H73-F195 VanDerWaalsContact CD2-CZ 3.49Å; H73-F195 WeakPolarHBondContact CD2-CZ 3.4Å; H73-F195 AromaticContact CE1-CE1 3.89Å; H73-F195 AromaticContact CE1-CE2 3.56Å; H73-F195 AromaticContact CE1-CZ 3.52Å; H73-F195 PolarHBondContact CE1-O 3.13Å; H73-F195 AromaticContact CG-CE1 3.47Å; H73-F195 VanDerWaalsContact CG-CE1 3.47Å; H73-F195 AromaticContact CG-CZ 3.57Å; H73-F195 AromaticContact ND1-CD1 3.83Å; H73-F195 AromaticContact ND1-CE1 3.52Å; H73-F195 AromaticContact ND1-CZ 3.64Å; H73-F195 PolarHBondContact ND1-O 2.89Å; H73-F195 AromaticContact NE2-CE2 3.67Å; H73-F195 AromaticContact NE2-CZ 3.43Å; H73-F195 WeakPolarHBondContact NE2-CZ 3.44Å; Y75-F195 HydrophobicContact CE1-CZ 4.46Å; Y191-F195 HydrophobicContact CD2-CB 4.31Å; Y191-F195 HydrophobicContact CE2-CB 3.93Å; Y191-F195 HydrophobicContact CE2-CG 4.34Å; Y191-F195 VanDerWaalsContact O-CB 3.25Å; Y191-F195 WeakPolarHBondContact O-CB 3.41Å; Y191-F195 PolarHBondContact O-N 2.56Å; R193-F195 VanDerWaalsContact C-N 3.29Å; R193-F195 PolarHBondContact O-N 3.18Å; F195-L197 VanDerWaalsContact C-N 3.28Å; F195-L197 PolarHBondContact O-N 2.79Å; F195-G198 WeakPolarHBondContact O-CA 3.46Å; F195-G198 PolarHBondContact O-N 2.71Å; F195-S200 WeakPolarHBondContact CD2-O 3.44Å; F195-M201 HydrophobicContact CD2-CB 4.27Å; F195-M201 HydrophobicContact CE2-CB 4.44Å
196A97.3Very high96.1Very high2 Ų227.4 Ų27.42%0.01714%0.142CC..Hα-helixtrans-62.8-32.7178.400000113.3P34 L36 L68 E192 R193 G198P34-A196 HydrophobicContact CB-CB 3.57Å; P34-A196 HydrophobicContact CG-CB 3.62Å; L36-A196 HydrophobicContact CD1-CB 3.96Å; L36-A196 HydrophobicContact CD2-CB 4.4Å; L36-A196 HydrophobicContact CG-CB 4.39Å; L68-A196 HydrophobicContact CD1-CB 4.48Å; E192-A196 WeakPolarHBondContact O-CB 3.38Å; E192-A196 PolarHBondContact O-N 2.79Å; E192-A196 VanDerWaalsContact O-N 3.16Å; R193-A196 PolarHBondContact O-N 3.28Å; A196-G198 PolarHBondContact O-N 2.82Å
197L98.5Very high96.1Very high23 Ų2326.6 Ų26.612%0.1214%0.137CC..THydrogen-bonded Turntrans-70.2-10.4171.8-71.6175.4000113.4E40 L43 A44 N47 R193 F195 V199E40-L197 HydrophobicContact CB-CD2 4.13Å; E40-L197 WeakPolarHBondContact O-CD2 3.34Å; L43-L197 HydrophobicContact CB-CD2 4.09Å; L43-L197 HydrophobicContact CD2-CD2 4.08Å; L43-L197 HydrophobicContact CG-CD2 4.09Å; A44-L197 HydrophobicContact CB-CD2 4.1Å; N47-L197 VanDerWaalsContact CB-O 3.25Å; N47-L197 WeakPolarHBondContact CB-O 3.44Å; N47-L197 PolarHBondContact ND2-O 3.23Å; R193-L197 WeakPolarHBondContact O-CB 3.4Å; R193-L197 VanDerWaalsContact O-CG 3.25Å; R193-L197 WeakPolarHBondContact O-CG 3.21Å; R193-L197 PolarHBondContact O-N 3.11Å; F195-L197 VanDerWaalsContact C-N 3.28Å; F195-L197 PolarHBondContact O-N 2.79Å; L197-V199 HydrophobicContact CB-CG1 4.4Å; L197-V199 HydrophobicContact CB-CG2 4.16Å
198G98Very high96.3Very high20 Ų2024 Ų2421%0.20612%0.118CC..THydrogen-bonded Turntrans69.729.6-178.200000113.8M194 F195 A196M194-G198 PolarHBondContact O-N 3.2Å; F195-G198 WeakPolarHBondContact O-CA 3.46Å; F195-G198 PolarHBondContact O-N 2.71Å; A196-G198 PolarHBondContact O-N 2.82Å
199V98.2Very high96.7Very high75 Ų7521 Ų2146%0.45511%0.108SC..SBendtrans-110.9-9-179.5-59.50000113.6M194 L197M194-V199 HydrophobicContact CB-CG2 3.76Å; M194-V199 HydrophobicContact CG-CG2 3.89Å; M194-V199 VanDerWaalsContact O-CG2 3.27Å; M194-V199 WeakPolarHBondContact O-CG2 3.44Å; M194-V199 PolarHBondContact O-N 3.07Å; L197-V199 HydrophobicContact CB-CG1 4.4Å; L197-V199 HydrophobicContact CB-CG2 4.16Å
200S98.2Very high97Very high4 Ų415.7 Ų15.73%0.0288%0.083CC..  trans-151.5170.2173.7-152.80000111.5G179 M194 F195G179-S200 WeakPolarHBondContact CA-OG 3.22Å; M194-S200 PolarHBondContact O-N 2.84Å; F195-S200 WeakPolarHBondContact CD2-O 3.44Å
201M97.4Very high97.2Very high0 Ų012.9 Ų12.90%07%0.069CC..  trans-154.5156.4171.360.3172.3-97.700110.1Q130 F132 S158 G179 F195Q130-M201 VanDerWaalsContact C-CE 3.42Å; Q130-M201 HydrophobicContact CB-CE 3.8Å; Q130-M201 WeakPolarHBondContact O-CE 3.39Å; F132-M201 VanDerWaalsContact CA-SD 3.59Å; S158-M201 VanDerWaalsContact C-CG 3.46Å; S158-M201 VanDerWaalsContact C-SD 3.58Å; S158-M201 WeakPolarHBondContact O-CG 3.38Å; G179-M201 PolarHBondContact N-O 3.38Å; F195-M201 HydrophobicContact CD2-CB 4.27Å; F195-M201 HydrophobicContact CE2-CB 4.44Å
202Y97.8Very high97.3Very high3 Ų313.2 Ų13.21%0.0127%0.071CC..  trans-91.3111.9174.1178.3-123.4000110.2N128 G129 Q130 Y191 Q204 N590 G591 W596N128-Y202 WeakPolarHBondContact OD1-CD1 3.36Å; N128-Y202 WeakPolarHBondContact OD1-CE1 3.23Å; G129-Y202 CarbonylContact C-O 3.51Å; G129-Y202 WeakPolarHBondContact CA-O 3.41Å; Q130-Y202 PolarHBondContact N-O 2.78Å; Y191-Y202 WeakPolarHBondContact OH-CB 3.47Å; Y202-Q204 HydrophobicContact CE1-CB 4.05Å; Y202-Q204 HydrophobicContact CE1-CG 3.91Å; Y202-N590 WeakPolarHBondContact CD2-O 3.15Å; Y202-N590 WeakPolarHBondContact CE2-O 3.4Å; Y202-G591 WeakPolarHBondContact CE2-O 3.47Å; Y202-G591 PolarHBondContact OH-O 2.91Å; Y202-W596 AromaticContact CD2-CE3 3.99Å; Y202-W596 HydrophobicContact CD2-CE3 3.99Å
203G97.4Very high97.4Very high0 Ų011.7 Ų11.70%06%0.064CC..  trans-86.6-0.6-178.100000114.7M205 A207 G208G203-M205 PolarHBondContact O-N 2.98Å; G203-A207 WeakPolarHBondContact O-CB 3.42Å; G203-A207 PolarHBondContact O-N 3.22Å; G203-G208 PolarHBondContact O-N 3.23Å
204Q95.2Very high97.1Very high7 Ų78.9 Ų8.93%0.0335%0.054CC..THydrogen-bonded Turntrans48.9-129.3-168.3-142.3-76.7-19.600109.4Y125 Y202 A207 H589 N601Y125-Q204 HydrophobicContact CD2-CG 4.25Å; Y125-Q204 HydrophobicContact CE2-CB 4.33Å; Y125-Q204 HydrophobicContact CE2-CG 3.64Å; Y125-Q204 PolarHBondContact OH-OE1 3.38Å; Y202-Q204 HydrophobicContact CE1-CB 4.05Å; Y202-Q204 HydrophobicContact CE1-CG 3.91Å; Q204-A207 HydrophobicContact CB-CB 4.35Å; Q204-H589 WeakPolarHBondContact O-CB 3.48Å; Q204-H589 PolarHBondContact O-ND1 2.96Å; Q204-N601 PolarHBondContact O-ND2 3.29Å
205M97.3Very high96.5Very high3 Ų38.1 Ų8.12%0.0155%0.051CC..THydrogen-bonded Turntrans-105-70.2172-60.3-177.5163.400108.1G203 S209 D543 H544 H545 H589G203-M205 PolarHBondContact O-N 2.98Å; M205-S209 PolarHBondContact O-OG 3.18Å; M205-D543 WeakPolarHBondContact CB-OD1 3.29Å; M205-H544 HydrophobicContact CB-CB 3.75Å; M205-H544 HydrophobicContact CG-CB 3.77Å; M205-H544 PolarHBondContact O-CE1 2.96Å; M205-H544 PolarHBondContact O-NE2 3.39Å; M205-H544 HydrophobicContact SD-CB 4.04Å; M205-H545 HydrophobicContact CE-CB 4.24Å; M205-H545 HydrophobicContact SD-CB 4.04Å; M205-H589 PolarHBondContact O-CE1 3.25Å; M205-H589 PolarHBondContact O-ND1 3.36Å; M205-H589 VanDerWaalsContact O-ND1 3.16Å
206T97.9Very high96Very high0 Ų08.1 Ų8.10%05%0.051CC..THydrogen-bonded Turntrans-97.3-6.3-169.363.80000114.6N110 Y125 S209 Y210 C211 Y212 R450 D543N110-T206 PolarHBondContact ND2-O 2.99Å; Y125-T206 WeakPolarHBondContact CE1-OG1 3.41Å; Y125-T206 PolarHBondContact OH-N 2.94Å; Y125-T206 PolarHBondContact OH-OG1 2.8Å; T206-S209 WeakPolarHBondContact CA-OG 3.4Å; T206-Y210 PolarHBondContact O-N 3.34Å; T206-C211 VanDerWaalsContact CB-SG 3.6Å; T206-C211 PolarHBondContact O-N 3.07Å; T206-C211 VanDerWaalsContact O-N 3.08Å; T206-Y212 PolarHBondContact O-N 3.08Å; T206-Y212 WeakPolarHBondContact OG1-CB 3.38Å; T206-Y212 VanDerWaalsContact OG1-CD2 3.3Å; T206-Y212 WeakPolarHBondContact OG1-CD2 3.35Å; T206-R450 VanDerWaalsContact CG2-NH1 3.28Å; T206-D543 HydrophobicContact CG2-CB 4.16Å; T206-D543 WeakPolarHBondContact CG2-OD1 3.28Å
207A97.1Very high95.2Very high0 Ų08.7 Ų8.70%06%0.057CC..THydrogen-bonded Turntrans-71.6-56.3179.200000110.6N110 Y125 G129 Q130 G203 Q204 S209N110-A207 PolarHBondContact ND2-O 3.43Å; Y125-A207 HydrophobicContact CD1-CB 4.13Å; Y125-A207 HydrophobicContact CE1-CB 3.83Å; G129-A207 WeakPolarHBondContact O-CB 3.36Å; Q130-A207 CarbonylContact O-C 3.51Å; G203-A207 WeakPolarHBondContact O-CB 3.42Å; G203-A207 PolarHBondContact O-N 3.22Å; Q204-A207 HydrophobicContact CB-CB 4.35Å; A207-S209 VanDerWaalsContact C-N 3.33Å; A207-S209 PolarHBondContact O-N 3.11Å
208G98.4Very high94.6Very high0 Ų08.9 Ų8.90%06%0.058CC..THydrogen-bonded Turntrans-80-10.2-178.600000114.7Q130 N178 G203 Y210Q130-G208 VanDerWaalsContact O-CA 3.3Å; Q130-G208 WeakPolarHBondContact O-CA 3.46Å; Q130-G208 PolarHBondContact O-N 2.78Å; Q130-G208 VanDerWaalsContact O-N 3.17Å; N178-G208 WeakPolarHBondContact ND2-CA 3.11Å; N178-G208 PolarHBondContact ND2-O 2.76Å; N178-G208 VanDerWaalsContact ND2-O 3.08Å; G203-G208 PolarHBondContact O-N 3.23Å; G208-Y210 WeakPolarHBondContact O-CE1 3.46Å
209S98.4Very high94.2Very high1 Ų18 Ų81%0.0075%0.048CC..THydrogen-bonded Turntrans-104.17.1177.562.60000113.1M205 T206 A207 C211 H544 W585 A587 H589M205-S209 PolarHBondContact O-OG 3.18Å; T206-S209 WeakPolarHBondContact CA-OG 3.4Å; A207-S209 VanDerWaalsContact C-N 3.33Å; A207-S209 PolarHBondContact O-N 3.11Å; S209-C211 PolarHBondContact OG-SG 3.37Å; S209-H544 PolarHBondContact OG-NE2 2.83Å; S209-W585 PolarHBondContact O-NE1 3.47Å; S209-A587 VanDerWaalsContact CB-CB 3.42Å; S209-H589 PolarHBondContact N-CE1 2.8Å
210Y98.3Very high93.9Very high4 Ų44.4 Ų4.42%0.0163%0.026CC..THydrogen-bonded Turntrans60.647.5171.3-38.5-40.6000112.6M106 I107 V131 F132 I176 T206 G208M106-Y210 WeakPolarHBondContact CB-O 3.36Å; M106-Y210 WeakPolarHBondContact CE-O 3.14Å; I107-Y210 HydrophobicContact CD1-CD2 3.95Å; I107-Y210 HydrophobicContact CD1-CE2 4.05Å; I107-Y210 HydrophobicContact CD1-CG 4.25Å; I107-Y210 HydrophobicContact CG1-CD1 3.71Å; I107-Y210 HydrophobicContact CG1-CD2 3.64Å; I107-Y210 HydrophobicContact CG1-CE1 4.18Å; I107-Y210 HydrophobicContact CG1-CE2 4.1Å; I107-Y210 HydrophobicContact CG1-CG 3.42Å; I107-Y210 VanDerWaalsContact CG1-CG 3.42Å; V131-Y210 HydrophobicContact CG1-CD1 3.69Å; V131-Y210 HydrophobicContact CG1-CE1 3.6Å; F132-Y210 HydrophobicContact CE1-CE1 4.15Å; F132-Y210 AromaticContact CE1-CZ 3.92Å; F132-Y210 VanDerWaalsContact CE1-OH 3.25Å; F132-Y210 WeakPolarHBondContact CE1-OH 3.4Å; F132-Y210 HydrophobicContact CZ-CE1 4.03Å; I176-Y210 HydrophobicContact CD1-CD2 3.74Å; I176-Y210 HydrophobicContact CD1-CE2 3.39Å; I176-Y210 HydrophobicContact CG1-CE2 4.25Å; T206-Y210 PolarHBondContact O-N 3.34Å; G208-Y210 WeakPolarHBondContact O-CE1 3.46Å
211C97.7Very high93.5Very high1 Ų14.7 Ų4.71%0.0073%0.03CC..  trans-143.318-179.767.70000115.5M106 T206 S209 R450 S541M106-C211 HydrophobicContact CE-CB 4.03Å; T206-C211 VanDerWaalsContact CB-SG 3.6Å; T206-C211 PolarHBondContact O-N 3.07Å; T206-C211 VanDerWaalsContact O-N 3.08Å; S209-C211 PolarHBondContact OG-SG 3.37Å; C211-R450 PolarHBondContact O-NE 3.44Å; C211-R450 VanDerWaalsContact O-NE 3.15Å; C211-R450 PolarHBondContact O-NH1 2.8Å; C211-R450 PolarHBondContact O-NH2 2.57Å; C211-S541 VanDerWaalsContact CB-OG 3.24Å; C211-S541 WeakPolarHBondContact CB-OG 3.37Å; C211-S541 PolarHBondContact SG-OG 3.36Å; C211-S541 VanDerWaalsContact SG-OG 3.4Å
212Y96.8Very high93.2Very high12 Ų124.8 Ų4.85%0.0473%0.031CC..  trans-71.1136.6176.7-173.5-108.6000110.5N109 N110 V115 T124 Y125 T206N109-Y212 PolarHBondContact ND2-O 3.48Å; N110-Y212 WeakPolarHBondContact OD1-CA 3.33Å; N110-Y212 WeakPolarHBondContact OD1-CB 3.39Å; N110-Y212 PolarHBondContact OD1-N 3.34Å; N110-Y212 PolarHBondContact OD1-O 3.07Å; V115-Y212 HydrophobicContact CG1-CD1 3.48Å; V115-Y212 VanDerWaalsContact CG1-CD1 3.48Å; V115-Y212 HydrophobicContact CG1-CE1 3.8Å; T124-Y212 HydrophobicContact CG2-CD1 3.37Å; T124-Y212 HydrophobicContact CG2-CE1 4.07Å; T124-Y212 HydrophobicContact CG2-CG 3.72Å; Y125-Y212 AromaticContact CD1-CD2 3.79Å; Y125-Y212 HydrophobicContact CD1-CD2 3.79Å; Y125-Y212 AromaticContact CD1-CE2 3.93Å; Y125-Y212 HydrophobicContact CD1-CE2 3.93Å; Y125-Y212 HydrophobicContact CD1-CG 4.14Å; Y125-Y212 AromaticContact CE1-CD2 3.59Å; Y125-Y212 HydrophobicContact CE1-CD2 3.59Å; Y125-Y212 HydrophobicContact CE1-CE2 4.04Å; Y125-Y212 HydrophobicContact CE1-CG 4.11Å; Y125-Y212 HydrophobicContact CG-CE2 4.22Å; T206-Y212 PolarHBondContact O-N 3.08Å; T206-Y212 WeakPolarHBondContact OG1-CB 3.38Å; T206-Y212 VanDerWaalsContact OG1-CD2 3.3Å; T206-Y212 WeakPolarHBondContact OG1-CD2 3.35Å
213I95Very high93Very high0 Ų04.8 Ų4.80%03%0.031CC..  trans-120.624.8-176.679.3-165.7000112.4Q216 R450 V452 A508 I510I213-Q216 HydrophobicContact CD1-CG 3.95Å; I213-Q216 HydrophobicContact CG1-CG 3.73Å; I213-R450 HydrophobicContact CD1-CB 4.33Å; I213-R450 VanDerWaalsContact N-NH2 3.13Å; I213-V452 HydrophobicContact CG2-CG2 3.88Å; I213-A508 HydrophobicContact CB-CB 3.61Å; I213-A508 HydrophobicContact CD1-CB 4.05Å; I213-A508 HydrophobicContact CG1-CB 4.17Å; I213-A508 HydrophobicContact CG2-CB 3.65Å; I213-I510 HydrophobicContact CD1-CB 4.06Å; I213-I510 HydrophobicContact CD1-CG2 4.32Å
214G88.9Confident92.8Very high2 Ų24.8 Ų4.82%0.0213%0.031CC..  trans76.5-165.9-171.100000112.7Q216G214-Q216 VanDerWaalsContact C-N 3.34Å; G214-Q216 PolarHBondContact O-N 3.11Å
215P84.7Confident92.7Very high14 Ų144.5 Ų4.59%0.0913%0.03CC..THydrogen-bonded Turntrans-82.8-5.2-162.934.3-40.2000114.7G217 I218 V219 W285P215-G217 PolarHBondContact O-N 3.23Å; P215-I218 PolarHBondContact O-N 2.82Å; P215-V219 PolarHBondContact O-N 2.97Å; P215-V219 VanDerWaalsContact O-N 3.08Å; P215-W285 HydrophobicContact CB-CH2 3.31Å; P215-W285 HydrophobicContact CB-CZ2 4.36Å; P215-W285 HydrophobicContact CB-CZ3 3.72Å; P215-W285 HydrophobicContact CG-CH2 3.09Å; P215-W285 HydrophobicContact CG-CZ2 3.68Å; P215-W285 HydrophobicContact CG-CZ3 3.86Å
216Q86.7Confident92.6Very high0 Ų04.4 Ų4.40%03%0.029CC..Hα-helixtrans-59.4-31.3179.863.4175.1-53.900113.8I213 G214 I218 V219 H220 M502 A508 R509 I510I213-Q216 HydrophobicContact CD1-CG 3.95Å; I213-Q216 HydrophobicContact CG1-CG 3.73Å; G214-Q216 VanDerWaalsContact C-N 3.34Å; G214-Q216 PolarHBondContact O-N 3.11Å; Q216-I218 VanDerWaalsContact C-N 3.3Å; Q216-I218 PolarHBondContact O-N 3.36Å; Q216-V219 PolarHBondContact O-N 3.05Å; Q216-H220 PolarHBondContact O-N 2.95Å; Q216-H220 VanDerWaalsContact O-N 3.07Å; Q216-M502 HydrophobicContact CB-CB 3.98Å; Q216-A508 PolarHBondContact NE2-O 3.04Å; Q216-A508 PolarHBondContact OE1-O 3.23Å; Q216-R509 VanDerWaalsContact OE1-NH1 3.17Å; Q216-I510 HydrophobicContact CG-CG2 4.3Å
217G81.4Confident92.4Very high13 Ų134.7 Ų4.713%0.1343%0.031CC..Hα-helixtrans-65.1-36.2175.900000112.9P215 G221P215-G217 PolarHBondContact O-N 3.23Å; G217-G221 PolarHBondContact O-N 3.35Å; G217-G221 VanDerWaalsContact O-N 3.11Å
218I85.4Confident92.2Very high28 Ų285.6 Ų5.614%0.1444%0.036CC..Hα-helixtrans-75.6-37.9176.7-46.7-59.3000110.2P215 Q216 H220 G221 T222 M252 A255P215-I218 PolarHBondContact O-N 2.82Å; Q216-I218 VanDerWaalsContact C-N 3.3Å; Q216-I218 PolarHBondContact O-N 3.36Å; I218-H220 VanDerWaalsContact C-N 3.3Å; I218-H220 PolarHBondContact O-N 3.28Å; I218-G221 PolarHBondContact O-N 2.81Å; I218-T222 WeakPolarHBondContact O-CB 3.21Å; I218-T222 PolarHBondContact O-N 3.37Å; I218-T222 PolarHBondContact O-OG1 3.04Å; I218-M252 HydrophobicContact CD1-CB 4.31Å; I218-M252 HydrophobicContact CD1-CG 4.06Å; I218-M252 HydrophobicContact CD1-SD 4.18Å; I218-M252 HydrophobicContact CG1-CB 3.95Å; I218-M252 HydrophobicContact CG1-CG 3.96Å; I218-M252 HydrophobicContact CG2-CB 4.29Å; I218-M252 WeakPolarHBondContact CG2-O 3.28Å; I218-A255 HydrophobicContact CB-CB 3.67Å; I218-A255 HydrophobicContact CG2-CB 3.71Å
219V90.3Very high92Very high0 Ų05.6 Ų5.60%04%0.036CC..Hα-helixtrans-58.3-45.9176.3178.40000110.6P215 Q216 M223 A255 K258 A259 I262 W285 W493 M502P215-V219 PolarHBondContact O-N 2.97Å; P215-V219 VanDerWaalsContact O-N 3.08Å; Q216-V219 PolarHBondContact O-N 3.05Å; V219-M223 VanDerWaalsContact O-CB 3.26Å; V219-M223 WeakPolarHBondContact O-CB 3.27Å; V219-M223 PolarHBondContact O-N 3.35Å; V219-A255 HydrophobicContact CB-CB 4.27Å; V219-A255 HydrophobicContact CG2-CB 3.47Å; V219-A255 VanDerWaalsContact CG2-CB 3.47Å; V219-K258 HydrophobicContact CG1-CB 4.14Å; V219-K258 HydrophobicContact CG1-CG 4.22Å; V219-K258 HydrophobicContact CG2-CB 4.22Å; V219-A259 HydrophobicContact CG1-CB 4.43Å; V219-I262 HydrophobicContact CG1-CD1 3.77Å; V219-W285 HydrophobicContact CG2-CH2 3.78Å; V219-W285 HydrophobicContact CG2-CZ2 4.44Å; V219-W285 HydrophobicContact CG2-CZ3 4.19Å; V219-W493 HydrophobicContact CB-CH2 4.21Å; V219-W493 HydrophobicContact CG1-CH2 4.06Å; V219-W493 HydrophobicContact CG1-CZ3 3.94Å; V219-M502 HydrophobicContact CB-SD 4.04Å; V219-M502 HydrophobicContact CG1-SD 3.8Å; V219-M502 HydrophobicContact CG2-SD 4.02Å
220H90.9Very high91.8Very high0 Ų05.6 Ų5.60%04%0.035CC..Hα-helixtrans-60.4-55.4176.7174.4-109.9000112.1Q216 I218 T222 M223 L224 N490 W493 I510 Y512Q216-H220 PolarHBondContact O-N 2.95Å; Q216-H220 VanDerWaalsContact O-N 3.07Å; I218-H220 VanDerWaalsContact C-N 3.3Å; I218-H220 PolarHBondContact O-N 3.28Å; H220-T222 VanDerWaalsContact C-N 3.31Å; H220-T222 PolarHBondContact O-N 3.49Å; H220-M223 PolarHBondContact O-N 3.11Å; H220-L224 WeakPolarHBondContact CE1-CD1 3.47Å; H220-L224 WeakPolarHBondContact NE2-CD1 3.21Å; H220-L224 PolarHBondContact O-N 3.47Å; H220-N490 PolarHBondContact CE1-OD1 3Å; H220-N490 VanDerWaalsContact CE1-OD1 3.23Å; H220-N490 PolarHBondContact NE2-OD1 3.32Å; H220-W493 HydrophobicContact CB-CD2 4.14Å; H220-W493 HydrophobicContact CB-CE3 4.46Å; H220-W493 HydrophobicContact CB-CH2 3.92Å; H220-W493 HydrophobicContact CB-CZ2 3.64Å; H220-W493 HydrophobicContact CB-CZ3 4.35Å; H220-W493 AromaticContact CD2-CD1 3.44Å; H220-W493 VanDerWaalsContact CD2-CD1 3.44Å; H220-W493 AromaticContact CD2-CD2 3.56Å; H220-W493 AromaticContact CD2-CE2 3.75Å; H220-W493 AromaticContact CD2-CG 3.36Å; H220-W493 AromaticContact CD2-NE1 3.65Å; H220-W493 AromaticContact CG-CE2 3.96Å; H220-W493 AromaticContact CG-NE1 3.96Å; H220-W493 AromaticContact NE2-CD1 3.97Å; H220-I510 HydrophobicContact CB-CG2 4.3Å; H220-Y512 AromaticContact CE1-CD1 3.3Å; H220-Y512 WeakPolarHBondContact CE1-CD1 3.39Å; H220-Y512 AromaticContact CE1-CG 3.74Å; H220-Y512 PolarHBondContact CE1-N 3.48Å; H220-Y512 AromaticContact ND1-CD1 3.6Å; H220-Y512 AromaticContact ND1-CE1 3.95Å
221G90.1Very high91.6Very high11 Ų117.8 Ų7.811%0.1134%0.044CC..Hα-helixtrans-58.7-41.818000000112.4G217 I218 L224 T225G217-G221 PolarHBondContact O-N 3.35Å; G217-G221 VanDerWaalsContact O-N 3.11Å; I218-G221 PolarHBondContact O-N 2.81Å; G221-L224 PolarHBondContact O-N 3.12Å; G221-T225 PolarHBondContact O-N 2.84Å; G221-T225 PolarHBondContact O-OG1 3.15Å; G221-T225 VanDerWaalsContact O-OG1 3.05Å
222T92.3Very high91.3Very high1 Ų113.8 Ų13.81%0.0067%0.066CC..Hα-helixtrans-68.4-38.4177.6-54.60000113.6I218 H220 L224 T225 V226 Q256 A259 Y403I218-T222 WeakPolarHBondContact O-CB 3.21Å; I218-T222 PolarHBondContact O-N 3.37Å; I218-T222 PolarHBondContact O-OG1 3.04Å; H220-T222 VanDerWaalsContact C-N 3.31Å; H220-T222 PolarHBondContact O-N 3.49Å; T222-L224 VanDerWaalsContact C-N 3.33Å; T222-L224 PolarHBondContact O-N 3.21Å; T222-T225 PolarHBondContact O-N 2.77Å; T222-V226 HydrophobicContact CG2-CG2 4.24Å; T222-V226 WeakPolarHBondContact O-CG2 3.47Å; T222-V226 PolarHBondContact O-N 3.37Å; T222-Q256 HydrophobicContact CG2-CB 4.36Å; T222-Q256 HydrophobicContact CG2-CG 4.07Å; T222-A259 HydrophobicContact CG2-CB 3.57Å; T222-Y403 WeakPolarHBondContact CA-OH 3.29Å; T222-Y403 VanDerWaalsContact CB-OH 3.23Å; T222-Y403 WeakPolarHBondContact CB-OH 3.4Å; T222-Y403 HydrophobicContact CG2-CE2 4.41Å; T222-Y403 WeakPolarHBondContact CG2-OH 3.48Å; T222-Y403 PolarHBondContact OG1-OH 3.39Å
223M93.5Very high91.2Very high4 Ų416 Ų162%0.028%0.075CC..Hα-helixtrans-60.6-45.7174.6175.8-84.3-72.100110.4V219 H220 T225 V226 L227 A259 I262 A263 W493V219-M223 VanDerWaalsContact O-CB 3.26Å; V219-M223 WeakPolarHBondContact O-CB 3.27Å; V219-M223 PolarHBondContact O-N 3.35Å; H220-M223 PolarHBondContact O-N 3.11Å; M223-T225 PolarHBondContact O-N 3.36Å; M223-V226 PolarHBondContact O-N 3.07Å; M223-L227 HydrophobicContact CG-CD1 4.34Å; M223-L227 WeakPolarHBondContact O-CG 3.17Å; M223-L227 PolarHBondContact O-N 3.11Å; M223-L227 HydrophobicContact SD-CD1 3.33Å; M223-L227 WeakPolarHBondContact SD-CD1 3.39Å; M223-L227 HydrophobicContact SD-CG 4.1Å; M223-A259 HydrophobicContact CB-CB 4.18Å; M223-I262 HydrophobicContact CG-CB 4.29Å; M223-I262 HydrophobicContact CG-CG2 3.85Å; M223-A263 HydrophobicContact CG-CB 4.45Å; M223-W493 HydrophobicContact CE-CB 3.76Å; M223-W493 HydrophobicContact CE-CD2 4.34Å; M223-W493 HydrophobicContact CE-CE3 3.93Å; M223-W493 HydrophobicContact CE-CG 4.3Å
224L91.9Very high91.2Very high0 Ų017.9 Ų17.90%09%0.085CC..Hα-helixtrans-61.3-43.8175.3-68.9-176.2000112.4H220 G221 T222 V226 L227 N228 D489 Y512H220-L224 WeakPolarHBondContact CE1-CD1 3.47Å; H220-L224 WeakPolarHBondContact NE2-CD1 3.21Å; H220-L224 PolarHBondContact O-N 3.47Å; G221-L224 PolarHBondContact O-N 3.12Å; T222-L224 VanDerWaalsContact C-N 3.33Å; T222-L224 PolarHBondContact O-N 3.21Å; L224-V226 PolarHBondContact O-N 2.85Å; L224-L227 PolarHBondContact O-N 3.09Å; L224-N228 WeakPolarHBondContact O-CB 3.38Å; L224-N228 PolarHBondContact O-N 3.5Å; L224-N228 PolarHBondContact O-ND2 2.95Å; L224-D489 HydrophobicContact CD2-CB 3.53Å; L224-Y512 HydrophobicContact CD1-CD1 4.47Å; L224-Y512 HydrophobicContact CD1-CD2 4.08Å; L224-Y512 HydrophobicContact CD1-CG 3.98Å
225T93.7Very high91.5Very high1 Ų121.1 Ų21.11%0.00612%0.118CC..Hα-helixtrans-59.4-47177.8-62.20000111.3G221 T222 M223 N228 A229 W401 Y403 Y433 I437G221-T225 PolarHBondContact O-N 2.84Å; G221-T225 PolarHBondContact O-OG1 3.15Å; G221-T225 VanDerWaalsContact O-OG1 3.05Å; T222-T225 PolarHBondContact O-N 2.77Å; M223-T225 PolarHBondContact O-N 3.36Å; T225-N228 PolarHBondContact O-N 3.19Å; T225-A229 VanDerWaalsContact O-CB 3.28Å; T225-A229 WeakPolarHBondContact O-CB 3.33Å; T225-A229 PolarHBondContact O-N 2.81Å; T225-W401 HydrophobicContact CG2-CZ2 4.19Å; T225-Y403 HydrophobicContact CG2-CE2 3.92Å; T225-Y433 HydrophobicContact CG2-CD2 4.04Å; T225-Y433 HydrophobicContact CG2-CG 4.36Å; T225-Y433 WeakPolarHBondContact OG1-CD2 3.29Å; T225-I437 HydrophobicContact CG2-CD1 4.03Å
226V94.8Very high91.9Very high0 Ų022.1 Ų22.10%012%0.124CC..Hα-helixtrans-67.7-42.2-178.5173.20000111.6T222 M223 L224 A229 G230 L239 F244 A263T222-V226 HydrophobicContact CG2-CG2 4.24Å; T222-V226 WeakPolarHBondContact O-CG2 3.47Å; T222-V226 PolarHBondContact O-N 3.37Å; M223-V226 PolarHBondContact O-N 3.07Å; L224-V226 PolarHBondContact O-N 2.85Å; V226-A229 PolarHBondContact O-N 3.03Å; V226-G230 PolarHBondContact O-N 3.1Å; V226-L239 HydrophobicContact CG1-CD1 3.63Å; V226-F244 HydrophobicContact CG2-CD1 4.11Å; V226-F244 HydrophobicContact CG2-CE1 4Å; V226-F244 HydrophobicContact CG2-CZ 4.38Å; V226-A263 HydrophobicContact CB-CB 4.35Å; V226-A263 HydrophobicContact CG1-CB 3.94Å
227L93.7Very high92Very high6 Ų626.8 Ų26.83%0.03115%0.149CC..Hα-helixtrans-61.1-46.7175.4-73-179.5000111.9M223 L224 G230 R231 L239 A263M223-L227 HydrophobicContact CG-CD1 4.34Å; M223-L227 WeakPolarHBondContact O-CG 3.17Å; M223-L227 PolarHBondContact O-N 3.11Å; M223-L227 HydrophobicContact SD-CD1 3.33Å; M223-L227 WeakPolarHBondContact SD-CD1 3.39Å; M223-L227 HydrophobicContact SD-CG 4.1Å; L224-L227 PolarHBondContact O-N 3.09Å; L227-G230 PolarHBondContact O-N 2.65Å; L227-R231 PolarHBondContact O-N 2.93Å; L227-L239 HydrophobicContact CD2-CD1 4.21Å; L227-A263 HydrophobicContact CD2-CB 4.05Å; L227-A263 HydrophobicContact CG-CB 4.26Å
228N92.6Very high92.7Very high20 Ų2029.1 Ų29.111%0.10716%0.158CC..Hα-helixtrans-71.1-32.5179.3-73.7-72.5000112.4L224 T225 G230 R231 R232 I437L224-N228 WeakPolarHBondContact O-CB 3.38Å; L224-N228 PolarHBondContact O-N 3.5Å; L224-N228 PolarHBondContact O-ND2 2.95Å; T225-N228 PolarHBondContact O-N 3.19Å; N228-G230 VanDerWaalsContact C-N 3.32Å; N228-R231 PolarHBondContact ND2-NH2 2.75Å; N228-R231 PolarHBondContact O-N 3.46Å; N228-R231 PolarHBondContact OD1-NE 3.43Å; N228-R231 PolarHBondContact OD1-NH2 2.83Å; N228-R232 VanDerWaalsContact O-CB 3.31Å; N228-R232 WeakPolarHBondContact O-CB 3.45Å; N228-R232 PolarHBondContact O-N 2.98Å; N228-I437 HydrophobicContact CB-CG2 3.32Å
229A94.1Very high93.2Very high0 Ų027.9 Ų27.90%015%0.152CC..Hα-helixtrans-61.5-43169.900000111.1T225 V226 R232 Y233 L339 W401 I437T225-A229 VanDerWaalsContact O-CB 3.28Å; T225-A229 WeakPolarHBondContact O-CB 3.33Å; T225-A229 PolarHBondContact O-N 2.81Å; V226-A229 PolarHBondContact O-N 3.03Å; A229-R232 PolarHBondContact O-N 2.93Å; A229-Y233 HydrophobicContact CB-CD2 4.17Å; A229-Y233 WeakPolarHBondContact O-CB 3.26Å; A229-Y233 WeakPolarHBondContact O-CD2 3.38Å; A229-Y233 PolarHBondContact O-N 3.02Å; A229-L339 HydrophobicContact CB-CD1 4.23Å; A229-L339 HydrophobicContact CB-CD2 4.39Å; A229-W401 HydrophobicContact CB-CH2 4.36Å; A229-W401 HydrophobicContact CB-CZ3 4.25Å; A229-I437 HydrophobicContact CB-CD1 3.83Å
230G95.2Very high93.5Very high0 Ų034.5 Ų34.50%018%0.177CC..Hα-helixtrans-52.7-53.5172.200000113.5V226 L227 N228 L234 G235 T236V226-G230 PolarHBondContact O-N 3.1Å; L227-G230 PolarHBondContact O-N 2.65Å; N228-G230 VanDerWaalsContact C-N 3.32Å; G230-L234 CarbonylContact O-C 3.59Å; G230-L234 WeakPolarHBondContact O-CA 3.24Å; G230-L234 VanDerWaalsContact O-CB 3.31Å; G230-L234 WeakPolarHBondContact O-CB 3.45Å; G230-L234 PolarHBondContact O-N 3.28Å; G230-G235 PolarHBondContact O-N 2.93Å; G230-T236 CarbonylContact C-O 3.13Å; G230-T236 PolarHBondContact O-N 2.94Å
231R93.1Very high93.8Very high51 Ų5135 Ų3519%0.19218%0.182CC..Hα-helixtrans-60.3-48.6176.8-77.8-175.7-79.4-90.79.4112.6L227 N228 G235 T236 D237 D489L227-R231 PolarHBondContact O-N 2.93Å; N228-R231 PolarHBondContact ND2-NH2 2.75Å; N228-R231 PolarHBondContact O-N 3.46Å; N228-R231 PolarHBondContact OD1-NE 3.43Å; N228-R231 PolarHBondContact OD1-NH2 2.83Å; R231-G235 WeakPolarHBondContact O-CA 3.37Å; R231-G235 PolarHBondContact O-N 3.49Å; R231-T236 PolarHBondContact N-O 2.92Å; R231-D237 WeakPolarHBondContact CD-OD1 3.25Å; R231-D237 WeakPolarHBondContact CG-OD1 3.08Å; R231-D237 IonicContact CZ-OD1 3.22Å; R231-D237 IonicContact NE-OD1 3.09Å; R231-D237 IonicContact NH1-OD1 3.32Å; R231-D237 PolarHBondContact NH1-OD1 3.17Å; R231-D489 IonicContact CZ-OD2 2.74Å; R231-D489 IonicContact NH1-OD1 2.74Å; R231-D489 IonicContact NH1-OD2 3.05Å; R231-D489 IonicContact NH2-OD1 3.68Å; R231-D489 IonicContact NH2-OD2 3.68Å; R231-D489 PolarHBondContact NH2-OD2 3.19Å
232R92.1Very high94.2Very high126 Ų12638.6 Ų38.648%0.47519%0.192SC..Hα-helixtrans-74.1-40.8-171-171.6169.9-177.1128.72.8113N228 A229 H436 D440N228-R232 VanDerWaalsContact O-CB 3.31Å; N228-R232 WeakPolarHBondContact O-CB 3.45Å; N228-R232 PolarHBondContact O-N 2.98Å; A229-R232 PolarHBondContact O-N 2.93Å; R232-H436 VanDerWaalsContact CD-O 3.25Å; R232-H436 WeakPolarHBondContact CD-O 3.42Å; R232-H436 PolarHBondContact NE-O 3.19Å; R232-H436 PolarHBondContact NH1-O 2.97Å; R232-D440 IonicContact NH1-OD2 3.86Å; R232-D440 PolarHBondContact NH1-OD2 3.47Å
233Y94.1Very high94.5Very high59 Ų5938.6 Ų38.623%0.23119%0.192CC..Hα-helixtrans-110.3-25.7-168.9-56.7-63.8000113.9A229 F399 H436 I437A229-Y233 HydrophobicContact CB-CD2 4.17Å; A229-Y233 WeakPolarHBondContact O-CB 3.26Å; A229-Y233 WeakPolarHBondContact O-CD2 3.38Å; A229-Y233 PolarHBondContact O-N 3.02Å; Y233-F399 HydrophobicContact CD1-CD1 4.18Å; Y233-F399 AromaticContact CD1-CD2 3.51Å; Y233-F399 HydrophobicContact CD1-CD2 3.51Å; Y233-F399 HydrophobicContact CD1-CE1 4.12Å; Y233-F399 AromaticContact CD1-CE2 3.42Å; Y233-F399 HydrophobicContact CD1-CE2 3.42Å; Y233-F399 VanDerWaalsContact CD1-CE2 3.42Å; Y233-F399 AromaticContact CD1-CG 3.91Å; Y233-F399 HydrophobicContact CD1-CG 3.91Å; Y233-F399 AromaticContact CD1-CZ 3.77Å; Y233-F399 HydrophobicContact CD1-CZ 3.77Å; Y233-F399 AromaticContact CD2-CD1 3.37Å; Y233-F399 HydrophobicContact CD2-CD1 3.37Å; Y233-F399 HydrophobicContact CD2-CD2 4.24Å; Y233-F399 AromaticContact CD2-CE1 3.35Å; Y233-F399 HydrophobicContact CD2-CE1 3.35Å; Y233-F399 HydrophobicContact CD2-CE2 4.22Å; Y233-F399 AromaticContact CD2-CG 3.85Å; Y233-F399 HydrophobicContact CD2-CG 3.85Å; Y233-F399 AromaticContact CD2-CZ 3.82Å; Y233-F399 HydrophobicContact CD2-CZ 3.82Å; Y233-F399 HydrophobicContact CE1-CD1 4.43Å; Y233-F399 AromaticContact CE1-CD2 3.84Å; Y233-F399 HydrophobicContact CE1-CD2 3.84Å; Y233-F399 AromaticContact CE1-CE1 3.9Å; Y233-F399 HydrophobicContact CE1-CE1 3.9Å; Y233-F399 AromaticContact CE1-CE2 3.21Å; Y233-F399 HydrophobicContact CE1-CE2 3.21Å; Y233-F399 HydrophobicContact CE1-CG 4.41Å; Y233-F399 AromaticContact CE1-CZ 3.27Å; Y233-F399 HydrophobicContact CE1-CZ 3.27Å; Y233-F399 AromaticContact CE2-CD1 3.67Å; Y233-F399 HydrophobicContact CE2-CD1 3.67Å; Y233-F399 AromaticContact CE2-CE1 3.08Å; Y233-F399 HydrophobicContact CE2-CE1 3.08Å; Y233-F399 HydrophobicContact CE2-CE2 4.06Å; Y233-F399 HydrophobicContact CE2-CG 4.37Å; Y233-F399 AromaticContact CE2-CZ 3.33Å; Y233-F399 HydrophobicContact CE2-CZ 3.33Å; Y233-F399 HydrophobicContact CG-CB 4.38Å; Y233-F399 AromaticContact CG-CD1 3.64Å; Y233-F399 HydrophobicContact CG-CD1 3.64Å; Y233-F399 AromaticContact CG-CD2 3.71Å; Y233-F399 HydrophobicContact CG-CD2 3.71Å; Y233-F399 AromaticContact CG-CE1 3.85Å; Y233-F399 HydrophobicContact CG-CE1 3.85Å; Y233-F399 AromaticContact CG-CE2 3.92Å; Y233-F399 HydrophobicContact CG-CE2 3.92Å; Y233-F399 AromaticContact CG-CG 3.58Å; Y233-F399 HydrophobicContact CG-CG 3.58Å; Y233-F399 AromaticContact CG-CZ 4Å; Y233-F399 HydrophobicContact CG-CZ 4Å; Y233-F399 AromaticContact CZ-CE1 3.36Å; Y233-F399 AromaticContact CZ-CE2 3.53Å; Y233-F399 AromaticContact CZ-CZ 2.99Å; Y233-F399 VanDerWaalsContact OH-CZ 3.23Å; Y233-F399 WeakPolarHBondContact OH-CZ 3.44Å; Y233-H436 WeakPolarHBondContact OH-CB 3.32Å; Y233-H436 PolarHBondContact OH-ND1 3Å; Y233-H436 VanDerWaalsContact OH-ND1 3.11Å; Y233-I437 HydrophobicContact CE2-CD1 4.19Å; Y233-I437 HydrophobicContact CE2-CG1 4.22Å
234L95.1Very high94.7Very high40 Ų4038.4 Ų38.421%0.20919%0.191CC..Hα-helixtrans-106-6.6176.3-51.3-177.4000112.7G230 T236 L239 R242 D338 L339G230-L234 CarbonylContact O-C 3.59Å; G230-L234 WeakPolarHBondContact O-CA 3.24Å; G230-L234 VanDerWaalsContact O-CB 3.31Å; G230-L234 WeakPolarHBondContact O-CB 3.45Å; G230-L234 PolarHBondContact O-N 3.28Å; L234-T236 VanDerWaalsContact C-N 3.27Å; L234-T236 HydrophobicContact CB-CG2 3.88Å; L234-T236 PolarHBondContact O-N 3.01Å; L234-L239 HydrophobicContact CD1-CD2 4.34Å; L234-R242 HydrophobicContact CD1-CB 4.27Å; L234-R242 HydrophobicContact CD1-CG 3.93Å; L234-D338 HydrophobicContact CD1-CB 3.97Å; L234-D338 HydrophobicContact CD2-CB 4.06Å; L234-L339 HydrophobicContact CD1-CD1 4.05Å; L234-L339 HydrophobicContact CD1-CD2 4.18Å; L234-L339 HydrophobicContact CD1-CG 3.95Å; L234-L339 HydrophobicContact CD2-CD2 4.25Å; L234-L339 HydrophobicContact CG-CD2 4.09Å; L234-L339 HydrophobicContact CG-CG 4.42Å
235G95.1Very high95Very high70 Ų7038.4 Ų38.472%0.72219%0.191SC*.SBendtrans64.426.3179.800000114.1G230 R231G230-G235 PolarHBondContact O-N 2.93Å; R231-G235 WeakPolarHBondContact O-CA 3.37Å; R231-G235 PolarHBondContact O-N 3.49Å
236T93.6Very high95.3Very high34 Ų3438.4 Ų38.421%0.20919%0.191CC..  trans-139141.8-174.9-177.40000112.7G230 R231 L234 D238 L239G230-T236 CarbonylContact C-O 3.13Å; G230-T236 PolarHBondContact O-N 2.94Å; R231-T236 PolarHBondContact N-O 2.92Å; L234-T236 VanDerWaalsContact C-N 3.27Å; L234-T236 HydrophobicContact CB-CG2 3.88Å; L234-T236 PolarHBondContact O-N 3.01Å; T236-D238 WeakPolarHBondContact CG2-O 3.48Å; T236-D238 PolarHBondContact OG1-N 3.23Å; T236-D238 PolarHBondContact OG1-O 3.46Å; T236-L239 HydrophobicContact CG2-CD2 4.11Å
237D89.7Confident95.4Very high98 Ų9838.4 Ų38.452%0.52419%0.191SC..SBendtrans-88.2-12.4167.3-77.9-58.6000113R231R231-D237 WeakPolarHBondContact CD-OD1 3.25Å; R231-D237 WeakPolarHBondContact CG-OD1 3.08Å; R231-D237 IonicContact CZ-OD1 3.22Å; R231-D237 IonicContact NE-OD1 3.09Å; R231-D237 IonicContact NH1-OD1 3.32Å; R231-D237 PolarHBondContact NH1-OD1 3.17Å
238D94.6Very high95.4Very high62 Ų6238.4 Ų38.433%0.33219%0.192SC..  trans-103.4110.8176.6-175.910.2000110.2T236 R240T236-D238 WeakPolarHBondContact CG2-O 3.48Å; T236-D238 PolarHBondContact OG1-N 3.23Å; T236-D238 PolarHBondContact OG1-O 3.46Å; D238-R240 VanDerWaalsContact OD1-CB 3.27Å; D238-R240 WeakPolarHBondContact OD1-CB 3.13Å; D238-R240 WeakPolarHBondContact OD1-CG 3.4Å; D238-R240 IonicContact OD1-CZ 3.78Å; D238-R240 PolarHBondContact OD1-N 3.19Å; D238-R240 IonicContact OD1-NE 2.87Å; D238-R240 PolarHBondContact OD1-NE 3.32Å; D238-R240 IonicContact OD1-NH2 3.83Å; D238-R240 IonicContact OD2-CZ 3.29Å; D238-R240 VanDerWaalsContact OD2-CZ 3.29Å; D238-R240 IonicContact OD2-NE 3.08Å; D238-R240 PolarHBondContact OD2-NE 3.38Å; D238-R240 VanDerWaalsContact OD2-NE 3.08Å; D238-R240 IonicContact OD2-NH2 2.68Å; D238-R240 PolarHBondContact OD2-NH2 2.82Å
239L96.9Very high95.4Very high2 Ų237.4 Ų37.41%0.0119%0.187CC..  trans-96.47.9179.8-56.3-179.9000113.9V226 L227 L234 T236 G241 R242 A263 G264 C265V226-L239 HydrophobicContact CG1-CD1 3.63Å; L227-L239 HydrophobicContact CD2-CD1 4.21Å; L234-L239 HydrophobicContact CD1-CD2 4.34Å; T236-L239 HydrophobicContact CG2-CD2 4.11Å; L239-G241 PolarHBondContact O-N 3.47Å; L239-R242 HydrophobicContact CB-CB 4.35Å; L239-R242 HydrophobicContact CB-CG 4.45Å; L239-R242 HydrophobicContact CD2-CB 4.49Å; L239-R242 HydrophobicContact CD2-CG 4.21Å; L239-R242 WeakPolarHBondContact O-CB 3.38Å; L239-R242 PolarHBondContact O-N 3.04Å; L239-A263 HydrophobicContact CD1-CB 4.26Å; L239-G264 CarbonylContact C-O 3.5Å; L239-C265 HydrophobicContact CB-CB 3.78Å; L239-C265 WeakPolarHBondContact O-CA 3.18Å
240R97.4Very high94.9Very high140 Ų14038.6 Ų38.653%0.52820%0.199SC..THydrogen-bonded Turntrans-61.2122.5175.8-69.5178-63.9174.60.8110.7D238 R242 G264 K307D238-R240 VanDerWaalsContact OD1-CB 3.27Å; D238-R240 WeakPolarHBondContact OD1-CB 3.13Å; D238-R240 WeakPolarHBondContact OD1-CG 3.4Å; D238-R240 IonicContact OD1-CZ 3.78Å; D238-R240 PolarHBondContact OD1-N 3.19Å; D238-R240 IonicContact OD1-NE 2.87Å; D238-R240 PolarHBondContact OD1-NE 3.32Å; D238-R240 IonicContact OD1-NH2 3.83Å; D238-R240 IonicContact OD2-CZ 3.29Å; D238-R240 VanDerWaalsContact OD2-CZ 3.29Å; D238-R240 IonicContact OD2-NE 3.08Å; D238-R240 PolarHBondContact OD2-NE 3.38Å; D238-R240 VanDerWaalsContact OD2-NE 3.08Å; D238-R240 IonicContact OD2-NH2 2.68Å; D238-R240 PolarHBondContact OD2-NH2 2.82Å; R240-R242 VanDerWaalsContact C-N 3.3Å; R240-G264 VanDerWaalsContact CA-O 3.31Å; R240-G264 WeakPolarHBondContact CA-O 3.38Å; R240-G264 PolarHBondContact N-O 3.33Å; R240-K307 HydrophobicContact CB-CB 4.13Å
241G95.9Very high94Very high10 Ų1039.7 Ų39.710%0.10321%0.211CC..THydrogen-bonded Turntrans79.55.9-175.200000114.7L239 R304L239-G241 PolarHBondContact O-N 3.47Å; G241-R304 WeakPolarHBondContact O-CG 3.46Å
242R98.1Very high93.5Very high86 Ų8639.4 Ų39.433%0.32521%0.212SC..  trans-87.5145.6166.2-58.7-58.1-173.9168.7-0.5110.3L234 L239 R240 C265 V266 D338L234-R242 HydrophobicContact CD1-CB 4.27Å; L234-R242 HydrophobicContact CD1-CG 3.93Å; L239-R242 HydrophobicContact CB-CB 4.35Å; L239-R242 HydrophobicContact CB-CG 4.45Å; L239-R242 HydrophobicContact CD2-CB 4.49Å; L239-R242 HydrophobicContact CD2-CG 4.21Å; L239-R242 WeakPolarHBondContact O-CB 3.38Å; L239-R242 PolarHBondContact O-N 3.04Å; R240-R242 VanDerWaalsContact C-N 3.3Å; R242-C265 WeakPolarHBondContact O-CB 3.43Å; R242-V266 PolarHBondContact O-N 3.5Å; R242-D338 WeakPolarHBondContact CA-OD2 2.95Å; R242-D338 IonicContact CZ-OD1 3.47Å; R242-D338 IonicContact NH1-OD1 3.28Å; R242-D338 PolarHBondContact NH1-OD1 3.3Å
243V98.6Very high93.3Very high1 Ų133.9 Ų33.91%0.00619%0.193CC..EExtended strand (participates in β ladder)trans-111.4124-176.4-176.50000110.2V245 V266 V268 I300 R304 L336 D338 L339V243-V245 HydrophobicContact CG1-CG2 4.13Å; V243-V266 CarbonylContact C-O 3.6Å; V243-V266 WeakPolarHBondContact CA-O 3.27Å; V243-V266 HydrophobicContact CG2-CB 4.17Å; V243-V266 HydrophobicContact CG2-CG1 4.47Å; V243-V268 HydrophobicContact CG1-CG2 4.4Å; V243-I300 HydrophobicContact CG1-CG2 4.03Å; V243-I300 HydrophobicContact CG2-CG2 3.88Å; V243-R304 HydrophobicContact CG2-CB 4.4Å; V243-R304 HydrophobicContact CG2-CG 4.28Å; V243-L336 VanDerWaalsContact CB-O 3.26Å; V243-L336 WeakPolarHBondContact CB-O 3.21Å; V243-L336 WeakPolarHBondContact CG1-O 3.35Å; V243-L336 VanDerWaalsContact CG2-O 3.32Å; V243-L336 WeakPolarHBondContact CG2-O 3.24Å; V243-D338 PolarHBondContact N-OD2 3.16Å; V243-D338 PolarHBondContact O-N 3.35Å; V243-D338 VanDerWaalsContact O-N 3.08Å; V243-L339 PolarHBondContact O-N 3.4Å
244F98.6Very high93Very high1 Ų131 Ų310%0.00418%0.182CC..EExtended strand (participates in β ladder)trans-112.5118.3174.5170.8-129.4000109.8V226 T246 A260 V266 G267 V268 L339 W401V226-F244 HydrophobicContact CG2-CD1 4.11Å; V226-F244 HydrophobicContact CG2-CE1 4Å; V226-F244 HydrophobicContact CG2-CZ 4.38Å; F244-T246 HydrophobicContact CE1-CG2 3.75Å; F244-T246 HydrophobicContact CZ-CG2 3.75Å; F244-A260 HydrophobicContact CD1-CB 4.4Å; F244-V266 PolarHBondContact N-O 2.95Å; F244-G267 CarbonylContact O-C 3.57Å; F244-G267 WeakPolarHBondContact O-CA 3.44Å; F244-V268 PolarHBondContact O-N 3.3Å; F244-L339 CarbonylContact C-O 3.59Å; F244-L339 VanDerWaalsContact CA-O 3.3Å; F244-L339 WeakPolarHBondContact CA-O 3.35Å; F244-L339 HydrophobicContact CB-CB 4.33Å; F244-L339 HydrophobicContact CD2-CB 3.98Å; F244-W401 AromaticContact CD2-CH2 3.68Å; F244-W401 HydrophobicContact CD2-CH2 3.68Å; F244-W401 HydrophobicContact CD2-CZ2 4.34Å; F244-W401 HydrophobicContact CD2-CZ3 4.47Å; F244-W401 AromaticContact CE2-CH2 3.33Å; F244-W401 HydrophobicContact CE2-CH2 3.33Å; F244-W401 AromaticContact CE2-CZ2 3.56Å; F244-W401 HydrophobicContact CE2-CZ2 3.56Å; F244-W401 HydrophobicContact CE2-CZ3 4.29Å; F244-W401 HydrophobicContact CZ-CH2 4.15Å; F244-W401 AromaticContact CZ-CZ2 3.99Å; F244-W401 HydrophobicContact CZ-CZ2 3.99Å
245V98.7Very high92.8Very high0 Ų029.1 Ų29.10%017%0.172CC..EExtended strand (participates in β ladder)trans-108.8132.2178.2179.40000109.8V243 V268 L321 W322 L325 V337 L339 G340 S341V243-V245 HydrophobicContact CG1-CG2 4.13Å; V245-V268 WeakPolarHBondContact CA-O 3.32Å; V245-V268 HydrophobicContact CG2-CB 4.21Å; V245-V268 HydrophobicContact CG2-CG2 4.48Å; V245-L321 HydrophobicContact CG1-CD2 3.75Å; V245-L321 HydrophobicContact CG1-CG 4.33Å; V245-W322 HydrophobicContact CB-CH2 3.67Å; V245-W322 HydrophobicContact CB-CZ2 4.19Å; V245-W322 HydrophobicContact CB-CZ3 4.11Å; V245-W322 HydrophobicContact CG1-CE3 4.48Å; V245-W322 HydrophobicContact CG1-CH2 3.73Å; V245-W322 HydrophobicContact CG1-CZ2 3.84Å; V245-W322 HydrophobicContact CG1-CZ3 4.07Å; V245-L325 HydrophobicContact CG1-CD1 4.18Å; V245-L325 HydrophobicContact CG2-CD1 3.96Å; V245-V337 HydrophobicContact CB-CG2 3.94Å; V245-V337 HydrophobicContact CG2-CB 4.04Å; V245-V337 HydrophobicContact CG2-CG2 3.55Å; V245-L339 PolarHBondContact N-O 3.27Å; V245-G340 WeakPolarHBondContact O-CA 3.33Å; V245-S341 PolarHBondContact O-N 3.05Å
246T98.5Very high92.7Very high0 Ų025.8 Ų25.80%014%0.137CC..EExtended strand (participates in β ladder)trans-152.4-173.3178.5-169.90000111.7F244 Q256 V268 I269 A270 S341F244-T246 HydrophobicContact CE1-CG2 3.75Å; F244-T246 HydrophobicContact CZ-CG2 3.75Å; T246-Q256 HydrophobicContact CG2-CB 4.02Å; T246-Q256 HydrophobicContact CG2-CG 4.4Å; T246-Q256 VanDerWaalsContact CG2-OE1 3.25Å; T246-Q256 PolarHBondContact OG1-OE1 3.23Å; T246-V268 PolarHBondContact N-O 3.46Å; T246-I269 HydrophobicContact CG2-CB 4.43Å; T246-I269 HydrophobicContact CG2-CG1 3.77Å; T246-I269 HydrophobicContact CG2-CG2 4.28Å; T246-I269 WeakPolarHBondContact O-CA 3.36Å; T246-A270 PolarHBondContact O-N 2.97Å; T246-S341 WeakPolarHBondContact CA-O 3.2Å
247S97.6Very high92.7Very high0 Ų024.2 Ų24.20%013%0.127CC..EExtended strand (participates in β ladder)trans-137.4155.1-173.961.90000113.3Q256 A270 D342 Q343S247-Q256 PolarHBondContact O-NE2 2.9Å; S247-A270 CarbonylContact C-O 3.59Å; S247-A270 WeakPolarHBondContact CA-O 3.09Å; S247-D342 WeakPolarHBondContact CB-OD2 3.4Å; S247-D342 WeakPolarHBondContact OG-CA 3.28Å; S247-D342 PolarHBondContact OG-OD2 2.88Å; S247-Q343 PolarHBondContact OG-N 2.95Å; S247-Q343 VanDerWaalsContact OG-N 3.07Å
248G94.2Very high92.9Very high6 Ų621.2 Ų21.26%0.06211%0.11CC..  trans84.5131.4175.600000113.5S253 Q256 I269 A270G248-S253 VanDerWaalsContact C-OG 3.24Å; G248-S253 CarbonylContact O-C 3.21Å; G248-S253 VanDerWaalsContact O-C 3.23Å; G248-S253 WeakPolarHBondContact O-CB 3.39Å; G248-S253 VanDerWaalsContact O-O 3.13Å; G248-S253 PolarHBondContact O-OG 3.29Å; G248-Q256 PolarHBondContact O-NE2 2.93Å; G248-I269 WeakPolarHBondContact O-CG2 3.43Å; G248-A270 PolarHBondContact N-O 3.17Å
249L92.1Very high92.9Very high0 Ų018.2 Ų18.20%09%0.094CC..  trans-12119.7173.1-69.9172.8000112.6A257 I269 E271 P276 L277 R280 V286L249-A257 HydrophobicContact CD2-CB 4.29Å; L249-I269 HydrophobicContact CD1-CG2 4.48Å; L249-I269 HydrophobicContact CD2-CB 4.06Å; L249-I269 HydrophobicContact CD2-CG2 3.59Å; L249-I269 HydrophobicContact CG-CB 4.42Å; L249-I269 HydrophobicContact CG-CG2 3.73Å; L249-E271 HydrophobicContact CB-CB 4.07Å; L249-E271 HydrophobicContact CB-CG 4.02Å; L249-E271 HydrophobicContact CD1-CB 3.77Å; L249-E271 HydrophobicContact CD1-CG 4.35Å; L249-E271 HydrophobicContact CG-CB 3.96Å; L249-E271 HydrophobicContact CG-CG 4.46Å; L249-E271 PolarHBondContact N-OE2 2.86Å; L249-P276 HydrophobicContact CB-CB 4.44Å; L249-P276 WeakPolarHBondContact O-CB 3.42Å; L249-L277 HydrophobicContact CD1-CB 3.96Å; L249-L277 HydrophobicContact CD1-CD1 4.22Å; L249-L277 HydrophobicContact CD1-CG 3.9Å; L249-R280 HydrophobicContact CB-CG 4.04Å; L249-R280 HydrophobicContact CD2-CG 4.23Å; L249-R280 PolarHBondContact O-NE 3.26Å; L249-R280 VanDerWaalsContact O-NE 3.15Å; L249-V286 HydrophobicContact CD1-CG2 3.99Å; L249-V286 HydrophobicContact CD2-CG2 3.87Å
250G83.8Confident92.8Very high24 Ų2418.1 Ų18.125%0.2479%0.093CC..SBendtrans-65.6-162.2177.200000114.1M252 S253 G254 R280G250-M252 PolarHBondContact O-N 2.61Å; G250-S253 PolarHBondContact N-OG 2.95Å; G250-S253 VanDerWaalsContact N-OG 3.11Å; G250-G254 PolarHBondContact O-N 3.13Å; G250-R280 PolarHBondContact O-NH2 3.33Å
251G76.9Confident92.6Very high24 Ų2413.4 Ų13.425%0.2478%0.08CC..THydrogen-bonded Turntrans-53.2-52.8-172.900000114R280G251-R280 PolarHBondContact O-NH2 3.25Å
252M82.4Confident92.4Very high44 Ų4413.4 Ų13.422%0.2178%0.078CC..THydrogen-bonded Turntrans-88.6-48.6176.7-63.6-177-7200112.1Y125 I218 G250 G254 A255Y125-M252 HydrophobicContact CD2-CE 3.95Å; Y125-M252 HydrophobicContact CD2-CG 3.97Å; Y125-M252 HydrophobicContact CD2-SD 3.67Å; Y125-M252 HydrophobicContact CE2-CE 4.19Å; Y125-M252 HydrophobicContact CE2-CG 4.37Å; Y125-M252 HydrophobicContact CE2-SD 3.6Å; Y125-M252 VanDerWaalsContact CE2-SD 3.6Å; I218-M252 HydrophobicContact CD1-CB 4.31Å; I218-M252 HydrophobicContact CD1-CG 4.06Å; I218-M252 HydrophobicContact CD1-SD 4.18Å; I218-M252 HydrophobicContact CG1-CB 3.95Å; I218-M252 HydrophobicContact CG1-CG 3.96Å; I218-M252 HydrophobicContact CG2-CB 4.29Å; I218-M252 WeakPolarHBondContact CG2-O 3.28Å; G250-M252 PolarHBondContact O-N 2.61Å; M252-G254 PolarHBondContact O-N 2.97Å; M252-A255 VanDerWaalsContact O-CB 3.23Å; M252-A255 WeakPolarHBondContact O-CB 3.43Å; M252-A255 PolarHBondContact O-N 2.72Å; M252-A255 VanDerWaalsContact O-N 3.07Å
253S88Confident92.2Very high10 Ų109.6 Ų9.67%0.076%0.064CC..THydrogen-bonded Turntrans-66.9-21.9-171.650.10000114.2G248 G250 A255 Q256 Q343G248-S253 VanDerWaalsContact C-OG 3.24Å; G248-S253 CarbonylContact O-C 3.21Å; G248-S253 VanDerWaalsContact O-C 3.23Å; G248-S253 WeakPolarHBondContact O-CB 3.39Å; G248-S253 VanDerWaalsContact O-O 3.13Å; G248-S253 PolarHBondContact O-OG 3.29Å; G250-S253 PolarHBondContact N-OG 2.95Å; G250-S253 VanDerWaalsContact N-OG 3.11Å; S253-A255 PolarHBondContact O-N 3.04Å; S253-A255 VanDerWaalsContact O-N 3.12Å; S253-Q256 WeakPolarHBondContact O-CB 3.24Å; S253-Q256 VanDerWaalsContact O-CG 3.27Å; S253-Q256 WeakPolarHBondContact O-CG 3.15Å; S253-Q256 PolarHBondContact O-N 3.01Å; S253-Q256 VanDerWaalsContact O-N 3.11Å; S253-Q256 PolarHBondContact O-NE2 2.89Å; S253-Q256 VanDerWaalsContact O-NE2 3.09Å; S253-Q343 VanDerWaalsContact CA-NE2 3.26Å; S253-Q343 WeakPolarHBondContact CB-O 3.13Å
254G87.6Confident92Very high0 Ų010 Ų100%07%0.069CC..THydrogen-bonded Turntrans-57.5-25.1170.500000114.5G250 M252 Q256 W285G250-G254 PolarHBondContact O-N 3.13Å; M252-G254 PolarHBondContact O-N 2.97Å; G254-Q256 VanDerWaalsContact C-N 3.25Å; G254-Q256 PolarHBondContact O-N 3.37Å; G254-W285 VanDerWaalsContact O-CE3 3.32Å
255A89.9Confident91.9Very high0 Ų010.1 Ų10.10%07%0.07CC..Hα-helixtrans-67.1-24.1178.400000113.8I218 V219 M252 S253 A257 K258 A259 W285I218-A255 HydrophobicContact CB-CB 3.67Å; I218-A255 HydrophobicContact CG2-CB 3.71Å; V219-A255 HydrophobicContact CB-CB 4.27Å; V219-A255 HydrophobicContact CG2-CB 3.47Å; V219-A255 VanDerWaalsContact CG2-CB 3.47Å; M252-A255 VanDerWaalsContact O-CB 3.23Å; M252-A255 WeakPolarHBondContact O-CB 3.43Å; M252-A255 PolarHBondContact O-N 2.72Å; M252-A255 VanDerWaalsContact O-N 3.07Å; S253-A255 PolarHBondContact O-N 3.04Å; S253-A255 VanDerWaalsContact O-N 3.12Å; A255-A257 PolarHBondContact O-N 2.84Å; A255-K258 PolarHBondContact O-N 2.96Å; A255-K258 VanDerWaalsContact O-N 3.14Å; A255-A259 WeakPolarHBondContact O-CB 3.25Å; A255-A259 PolarHBondContact O-N 2.95Å; A255-W285 HydrophobicContact CB-CZ3 4.13Å
256Q94Very high91.9Very high0 Ų010.1 Ų10.10%07%0.07CC..Hα-helixtrans-60.2-36.7-177.7-61.3177.297.800112T222 T246 S247 G248 S253 G254 K258 A259 A260T222-Q256 HydrophobicContact CG2-CB 4.36Å; T222-Q256 HydrophobicContact CG2-CG 4.07Å; T246-Q256 HydrophobicContact CG2-CB 4.02Å; T246-Q256 HydrophobicContact CG2-CG 4.4Å; T246-Q256 VanDerWaalsContact CG2-OE1 3.25Å; T246-Q256 PolarHBondContact OG1-OE1 3.23Å; S247-Q256 PolarHBondContact O-NE2 2.9Å; G248-Q256 PolarHBondContact O-NE2 2.93Å; S253-Q256 WeakPolarHBondContact O-CB 3.24Å; S253-Q256 VanDerWaalsContact O-CG 3.27Å; S253-Q256 WeakPolarHBondContact O-CG 3.15Å; S253-Q256 PolarHBondContact O-N 3.01Å; S253-Q256 VanDerWaalsContact O-N 3.11Å; S253-Q256 PolarHBondContact O-NE2 2.89Å; S253-Q256 VanDerWaalsContact O-NE2 3.09Å; G254-Q256 VanDerWaalsContact C-N 3.25Å; G254-Q256 PolarHBondContact O-N 3.37Å; Q256-K258 PolarHBondContact O-N 3.33Å; Q256-A259 PolarHBondContact O-N 2.91Å; Q256-A260 WeakPolarHBondContact O-CB 3.49Å; Q256-A260 PolarHBondContact O-N 2.9Å
257A93.9Very high91.9Very high0 Ų010.1 Ų10.10%07%0.07CC..Hα-helixtrans-58.3-48.217600000111.8L249 A255 I269 W285 V286 S311L249-A257 HydrophobicContact CD2-CB 4.29Å; A255-A257 PolarHBondContact O-N 2.84Å; A257-I269 HydrophobicContact CB-CD1 3.8Å; A257-I269 HydrophobicContact CB-CG1 4.41Å; A257-W285 WeakPolarHBondContact CB-O 3.31Å; A257-V286 HydrophobicContact CB-CG2 3.77Å; A257-S311 VanDerWaalsContact O-CB 3.27Å; A257-S311 WeakPolarHBondContact O-CB 3.28Å
258K92.8Very high92Very high35 Ų3510.1 Ų10.115%0.1527%0.07CC..Hα-helixtrans-71.2-40.7179.3-160.967.8167.5-175.20111.8V219 A255 Q256 A260 V261 I262 G284 W285 M502V219-K258 HydrophobicContact CG1-CB 4.14Å; V219-K258 HydrophobicContact CG1-CG 4.22Å; V219-K258 HydrophobicContact CG2-CB 4.22Å; A255-K258 PolarHBondContact O-N 2.96Å; A255-K258 VanDerWaalsContact O-N 3.14Å; Q256-K258 PolarHBondContact O-N 3.33Å; K258-A260 VanDerWaalsContact C-N 3.34Å; K258-A260 PolarHBondContact O-N 3.28Å; K258-V261 PolarHBondContact O-N 3Å; K258-I262 HydrophobicContact CG-CD1 4.02Å; K258-I262 WeakPolarHBondContact O-CG1 3.42Å; K258-I262 PolarHBondContact O-N 3.4Å; K258-G284 PolarHBondContact NZ-O 2.79Å; K258-W285 HydrophobicContact CB-CG 4.46Å; K258-M502 HydrophobicContact CG-SD 4.49Å
259A94.2Very high92.2Very high0 Ų09.9 Ų9.90%07%0.067CC..Hα-helixtrans-59.8-42179.400000112.5V219 T222 M223 A255 Q256 V261 I262 A263V219-A259 HydrophobicContact CG1-CB 4.43Å; T222-A259 HydrophobicContact CG2-CB 3.57Å; M223-A259 HydrophobicContact CB-CB 4.18Å; A255-A259 WeakPolarHBondContact O-CB 3.25Å; A255-A259 PolarHBondContact O-N 2.95Å; Q256-A259 PolarHBondContact O-N 2.91Å; A259-V261 VanDerWaalsContact C-N 3.34Å; A259-V261 PolarHBondContact O-N 3.48Å; A259-I262 PolarHBondContact O-N 2.9Å; A259-A263 VanDerWaalsContact O-CB 3.27Å; A259-A263 WeakPolarHBondContact O-CB 3.37Å; A259-A263 PolarHBondContact O-N 3.05Å
260A95.2Very high92.5Very high0 Ų010 Ų100%07%0.068CC..Hα-helixtrans-57.8-45.317600000112.1F244 Q256 K258 A263 G264 C265F244-A260 HydrophobicContact CD1-CB 4.4Å; Q256-A260 WeakPolarHBondContact O-CB 3.49Å; Q256-A260 PolarHBondContact O-N 2.9Å; K258-A260 VanDerWaalsContact C-N 3.34Å; K258-A260 PolarHBondContact O-N 3.28Å; A260-A263 PolarHBondContact O-N 2.95Å; A260-G264 PolarHBondContact O-N 3.37Å; A260-C265 PolarHBondContact O-N 2.97Å; A260-C265 PolarHBondContact O-SG 3.37Å
261V94.4Very high93.1Very high40 Ų409.9 Ų9.924%0.2426%0.061CC..Hα-helixtrans-66.3-42.6178.7176.20000111.7K258 A259 A263 G264 M287 P309K258-V261 PolarHBondContact O-N 3Å; A259-V261 VanDerWaalsContact C-N 3.34Å; A259-V261 PolarHBondContact O-N 3.48Å; V261-A263 VanDerWaalsContact C-N 3.35Å; V261-G264 WeakPolarHBondContact O-CA 3.47Å; V261-G264 PolarHBondContact O-N 2.88Å; V261-G264 VanDerWaalsContact O-N 3.07Å; V261-M287 HydrophobicContact CG1-SD 4.42Å; V261-M287 HydrophobicContact CG2-SD 3.82Å; V261-P309 HydrophobicContact CG1-CB 4.34Å
262I92.1Very high94Very high11 Ų1110.1 Ų10.16%0.0566%0.058CC..Hα-helixtrans-65.9-39.8177.6-63.3170.8000110.8V219 M223 K258 A259 G264 R492 W493V219-I262 HydrophobicContact CG1-CD1 3.77Å; M223-I262 HydrophobicContact CG-CB 4.29Å; M223-I262 HydrophobicContact CG-CG2 3.85Å; K258-I262 HydrophobicContact CG-CD1 4.02Å; K258-I262 WeakPolarHBondContact O-CG1 3.42Å; K258-I262 PolarHBondContact O-N 3.4Å; A259-I262 PolarHBondContact O-N 2.9Å; I262-G264 PolarHBondContact O-N 3.46Å; I262-R492 PolarHBondContact O-NH2 3.4Å; I262-W493 HydrophobicContact CD1-CZ3 4.12Å
263A93.1Very high94.4Very high5 Ų510.2 Ų10.24%0.0416%0.059CC..Hα-helixtrans-67.1-19.6173.400000112.6M223 V226 L227 L239 A259 A260 V261M223-A263 HydrophobicContact CG-CB 4.45Å; V226-A263 HydrophobicContact CB-CB 4.35Å; V226-A263 HydrophobicContact CG1-CB 3.94Å; L227-A263 HydrophobicContact CD2-CB 4.05Å; L227-A263 HydrophobicContact CG-CB 4.26Å; L239-A263 HydrophobicContact CD1-CB 4.26Å; A259-A263 VanDerWaalsContact O-CB 3.27Å; A259-A263 WeakPolarHBondContact O-CB 3.37Å; A259-A263 PolarHBondContact O-N 3.05Å; A260-A263 PolarHBondContact O-N 2.95Å; V261-A263 VanDerWaalsContact C-N 3.35Å
264G94.4Very high94.6Very high11 Ų1113.6 Ų13.611%0.1137%0.074CC..THydrogen-bonded Turntrans93.113175.100000114.8L239 R240 A260 V261 I262L239-G264 CarbonylContact C-O 3.5Å; R240-G264 VanDerWaalsContact CA-O 3.31Å; R240-G264 WeakPolarHBondContact CA-O 3.38Å; R240-G264 PolarHBondContact N-O 3.33Å; A260-G264 PolarHBondContact O-N 3.37Å; V261-G264 WeakPolarHBondContact O-CA 3.47Å; V261-G264 PolarHBondContact O-N 2.88Å; V261-G264 VanDerWaalsContact O-N 3.07Å; I262-G264 PolarHBondContact O-N 3.46Å
265C97Very high94.5Very high2 Ų216.6 Ų16.61%0.01410%0.098CC..SBendtrans-100.7174.6-177.973.20000113.4L239 R242 A260 P309 L310L239-C265 HydrophobicContact CB-CB 3.78Å; L239-C265 WeakPolarHBondContact O-CA 3.18Å; R242-C265 WeakPolarHBondContact O-CB 3.43Å; A260-C265 PolarHBondContact O-N 2.97Å; A260-C265 PolarHBondContact O-SG 3.37Å; C265-P309 WeakPolarHBondContact O-CA 3.5Å; C265-L310 PolarHBondContact O-N 3.34Å
266V98.5Very high94.3Very high0 Ų017.7 Ų17.70%011%0.105CC..EExtended strand (participates in β ladder)trans-89.4102.4169.8-178.60000108R242 V243 F244 A303 L310R242-V266 PolarHBondContact O-N 3.5Å; V243-V266 CarbonylContact C-O 3.6Å; V243-V266 WeakPolarHBondContact CA-O 3.27Å; V243-V266 HydrophobicContact CG2-CB 4.17Å; V243-V266 HydrophobicContact CG2-CG1 4.47Å; F244-V266 PolarHBondContact N-O 2.95Å; V266-A303 HydrophobicContact CB-CB 4.37Å; V266-A303 HydrophobicContact CG1-CB 3.82Å; V266-A303 HydrophobicContact CG2-CB 3.56Å; V266-L310 CarbonylContact C-O 3.4Å; V266-L310 HydrophobicContact CG1-CB 4.33Å; V266-L310 HydrophobicContact CG1-CD2 4.36Å
267G98.3Very high94.2Very high0 Ų017.9 Ų17.90%011%0.106CC..EExtended strand (participates in β ladder)trans-89.9128.3174.500000112.1F244 L310 S311 L312F244-G267 CarbonylContact O-C 3.57Å; F244-G267 WeakPolarHBondContact O-CA 3.44Å; G267-L310 PolarHBondContact N-O 2.79Å; G267-S311 WeakPolarHBondContact O-CA 3.42Å; G267-L312 PolarHBondContact O-N 3.36Å
268V98.6Very high94.1Very high0 Ų024.5 Ų24.50%013%0.132CC..EExtended strand (participates in β ladder)trans-119.1120.7172.8-171.40000108.7V243 F244 V245 T246 I300 L312 L321V243-V268 HydrophobicContact CG1-CG2 4.4Å; F244-V268 PolarHBondContact O-N 3.3Å; V245-V268 WeakPolarHBondContact CA-O 3.32Å; V245-V268 HydrophobicContact CG2-CB 4.21Å; V245-V268 HydrophobicContact CG2-CG2 4.48Å; T246-V268 PolarHBondContact N-O 3.46Å; V268-I300 HydrophobicContact CG2-CD1 3.82Å; V268-I300 HydrophobicContact CG2-CG1 3.67Å; V268-L312 WeakPolarHBondContact CA-O 3.44Å; V268-L321 HydrophobicContact CG1-CD2 3.8Å
269I98.4Very high93.7Very high1 Ų127.9 Ų27.91%0.00515%0.146CC..EExtended strand (participates in β ladder)trans-124.6112.5-172.1-52.186.9000109.2T246 G248 L249 A257 L312 G313 Y314T246-I269 HydrophobicContact CG2-CB 4.43Å; T246-I269 HydrophobicContact CG2-CG1 3.77Å; T246-I269 HydrophobicContact CG2-CG2 4.28Å; T246-I269 WeakPolarHBondContact O-CA 3.36Å; G248-I269 WeakPolarHBondContact O-CG2 3.43Å; L249-I269 HydrophobicContact CD1-CG2 4.48Å; L249-I269 HydrophobicContact CD2-CB 4.06Å; L249-I269 HydrophobicContact CD2-CG2 3.59Å; L249-I269 HydrophobicContact CG-CB 4.42Å; L249-I269 HydrophobicContact CG-CG2 3.73Å; A257-I269 HydrophobicContact CB-CD1 3.8Å; A257-I269 HydrophobicContact CB-CG1 4.41Å; I269-L312 PolarHBondContact N-O 3.45Å; I269-G313 WeakPolarHBondContact O-CA 3.2Å; I269-Y314 PolarHBondContact O-N 3.25Å
270A98.5Very high93.5Very high3 Ų328.6 Ų28.63%0.02515%0.149CC..EExtended strand (participates in β ladder)trans-81.6133.9175.300000111.3T246 S247 G248 Y314 V318 L321T246-A270 PolarHBondContact O-N 2.97Å; S247-A270 CarbonylContact C-O 3.59Å; S247-A270 WeakPolarHBondContact CA-O 3.09Å; G248-A270 PolarHBondContact N-O 3.17Å; A270-Y314 WeakPolarHBondContact CA-O 3.29Å; A270-Y314 HydrophobicContact CB-CD1 3.91Å; A270-V318 HydrophobicContact CB-CB 3.71Å; A270-V318 HydrophobicContact CB-CG2 4.02Å; A270-L321 HydrophobicContact CB-CD2 4.14Å
271E97.6Very high93.4Very high22 Ų2232.7 Ų32.710%0.10317%0.168CC..EExtended strand (participates in β ladder)trans-143.5132175173.759.9-99.400109.7L249 D273 P276 L277 Y314 H315 G316L249-E271 HydrophobicContact CB-CB 4.07Å; L249-E271 HydrophobicContact CB-CG 4.02Å; L249-E271 HydrophobicContact CD1-CB 3.77Å; L249-E271 HydrophobicContact CD1-CG 4.35Å; L249-E271 HydrophobicContact CG-CB 3.96Å; L249-E271 HydrophobicContact CG-CG 4.46Å; L249-E271 PolarHBondContact N-OE2 2.86Å; E271-D273 VanDerWaalsContact CG-O 3.23Å; E271-D273 WeakPolarHBondContact CG-O 3.24Å; E271-D273 PolarHBondContact OE1-N 3.25Å; E271-P276 HydrophobicContact CG-CG 3.98Å; E271-L277 HydrophobicContact CB-CB 4.35Å; E271-L277 HydrophobicContact CB-CD1 4.23Å; E271-L277 HydrophobicContact CG-CB 4.07Å; E271-Y314 PolarHBondContact N-O 3.09Å; E271-H315 CarbonylContact O-C 3.58Å; E271-H315 WeakPolarHBondContact O-CA 3.5Å; E271-G316 CarbonylContact C-O 3.56Å; E271-G316 PolarHBondContact O-N 3.14Å
272V95.5Very high93.2Very high29 Ų2938.2 Ų38.218%0.17619%0.191CC..SBendtrans-88.9-25.2-177.9-66.60000112.6N317 Y355 F361V272-N317 HydrophobicContact CG1-CB 4.1Å; V272-Y355 HydrophobicContact CG2-CD2 3.76Å; V272-Y355 HydrophobicContact CG2-CG 3.75Å; V272-F361 HydrophobicContact CG2-CD2 4.1Å
273D90.4Very high92.8Very high45 Ų4541.4 Ų41.424%0.24121%0.205CC..  trans-92.5117.8177.5-173.9-2.3000110.1E271 A275 P276 L277 F361E271-D273 VanDerWaalsContact CG-O 3.23Å; E271-D273 WeakPolarHBondContact CG-O 3.24Å; E271-D273 PolarHBondContact OE1-N 3.25Å; D273-A275 PolarHBondContact O-N 2.58Å; D273-A275 WeakPolarHBondContact OD1-CB 3.45Å; D273-A275 PolarHBondContact OD1-N 2.93Å; D273-P276 HydrophobicContact CB-CG 3.69Å; D273-P276 VanDerWaalsContact O-CD 3.23Å; D273-P276 WeakPolarHBondContact O-CD 3.29Å; D273-P276 WeakPolarHBondContact O-CG 3.43Å; D273-P276 WeakPolarHBondContact OD1-CD 3.5Å; D273-P276 VanDerWaalsContact OD2-CD 3.26Å; D273-P276 WeakPolarHBondContact OD2-CD 3.37Å; D273-L277 PolarHBondContact O-N 3.38Å; D273-F361 HydrophobicContact CB-CD2 4.11Å; D273-F361 HydrophobicContact CB-CE1 4.36Å; D273-F361 HydrophobicContact CB-CE2 3.64Å; D273-F361 HydrophobicContact CB-CZ 3.78Å; D273-F361 VanDerWaalsContact CG-CZ 3.42Å; D273-F361 WeakPolarHBondContact OD2-CZ 3.44Å
274E91.8Very high92.6Very high82 Ų8242.8 Ų42.838%0.38322%0.221SC..Hα-helixtrans-62.1-31179.5-173.1170.2-160.500112.5L277 R278E274-L277 PolarHBondContact O-N 2.83Å; E274-R278 VanDerWaalsContact CD-NE 3.35Å; E274-R278 HydrophobicContact CG-CG 3.96Å; E274-R278 WeakPolarHBondContact O-CB 3.39Å; E274-R278 WeakPolarHBondContact O-CG 2.98Å; E274-R278 PolarHBondContact O-N 3.25Å; E274-R278 IonicContact OE1-CZ 3.66Å; E274-R278 IonicContact OE1-NE 3.9Å; E274-R278 PolarHBondContact OE1-NE 2.89Å; E274-R278 IonicContact OE1-NH2 2.75Å; E274-R278 PolarHBondContact OE1-NH2 3.35Å
275A86.2Confident92.5Very high62 Ų6243 Ų4351%0.51222%0.218SC..Hα-helixtrans-63.3-55.7-176.200000113.7D273 L277 K279D273-A275 PolarHBondContact O-N 2.58Å; D273-A275 WeakPolarHBondContact OD1-CB 3.45Å; D273-A275 PolarHBondContact OD1-N 2.93Å; A275-L277 VanDerWaalsContact C-N 3.32Å; A275-L277 PolarHBondContact O-N 3.11Å; A275-K279 WeakPolarHBondContact O-CB 3.23Å; A275-K279 PolarHBondContact O-N 2.68Å
276P85.2Confident92.4Very high23 Ų2342.9 Ų42.915%0.14922%0.217CC..Hα-helixtrans-62.6-38.1174.723.2-32000111.9L249 E271 D273 K279 R280L249-P276 HydrophobicContact CB-CB 4.44Å; L249-P276 WeakPolarHBondContact O-CB 3.42Å; E271-P276 HydrophobicContact CG-CG 3.98Å; D273-P276 HydrophobicContact CB-CG 3.69Å; D273-P276 VanDerWaalsContact O-CD 3.23Å; D273-P276 WeakPolarHBondContact O-CD 3.29Å; D273-P276 WeakPolarHBondContact O-CG 3.43Å; D273-P276 WeakPolarHBondContact OD1-CD 3.5Å; D273-P276 VanDerWaalsContact OD2-CD 3.26Å; D273-P276 WeakPolarHBondContact OD2-CD 3.37Å; P276-K279 PolarHBondContact O-N 3.07Å; P276-R280 VanDerWaalsContact O-CG 3.31Å; P276-R280 WeakPolarHBondContact O-CG 3.36Å; P276-R280 PolarHBondContact O-N 2.95Å
277L91.7Very high92.3Very high4 Ų447.1 Ų47.12%0.02124%0.238CC..Hα-helixtrans-59.6-51.9178.3-177.1152.2000111.7L249 E271 D273 E274 A275 K279 R280 H281 V289 H315L249-L277 HydrophobicContact CD1-CB 3.96Å; L249-L277 HydrophobicContact CD1-CD1 4.22Å; L249-L277 HydrophobicContact CD1-CG 3.9Å; E271-L277 HydrophobicContact CB-CB 4.35Å; E271-L277 HydrophobicContact CB-CD1 4.23Å; E271-L277 HydrophobicContact CG-CB 4.07Å; D273-L277 PolarHBondContact O-N 3.38Å; E274-L277 PolarHBondContact O-N 2.83Å; A275-L277 VanDerWaalsContact C-N 3.32Å; A275-L277 PolarHBondContact O-N 3.11Å; L277-K279 VanDerWaalsContact C-N 3.34Å; L277-K279 PolarHBondContact O-N 2.93Å; L277-R280 PolarHBondContact O-N 3.09Å; L277-H281 PolarHBondContact O-N 3.31Å; L277-V289 HydrophobicContact CD1-CG1 4.49Å; L277-V289 HydrophobicContact CD2-CB 4.25Å; L277-V289 HydrophobicContact CD2-CG1 3.55Å; L277-V289 HydrophobicContact CD2-CG2 3.64Å; L277-H315 HydrophobicContact CD1-CB 3.76Å
278R91.4Very high92.3Very high140 Ų14050.4 Ų50.453%0.52825%0.253SS..Hα-helixtrans-60.2-44.7176.7-75.5-175.3177.7-146.66.1111.4E274 R280 H281 E282E274-R278 VanDerWaalsContact CD-NE 3.35Å; E274-R278 HydrophobicContact CG-CG 3.96Å; E274-R278 WeakPolarHBondContact O-CB 3.39Å; E274-R278 WeakPolarHBondContact O-CG 2.98Å; E274-R278 PolarHBondContact O-N 3.25Å; E274-R278 IonicContact OE1-CZ 3.66Å; E274-R278 IonicContact OE1-NE 3.9Å; E274-R278 PolarHBondContact OE1-NE 2.89Å; E274-R278 IonicContact OE1-NH2 2.75Å; E274-R278 PolarHBondContact OE1-NH2 3.35Å; R278-R280 VanDerWaalsContact C-N 3.3Å; R278-R280 PolarHBondContact O-N 2.79Å; R278-H281 WeakPolarHBondContact O-CB 3.28Å; R278-H281 PolarHBondContact O-N 3.47Å; R278-H281 VanDerWaalsContact O-N 3.08Å; R278-E282 WeakPolarHBondContact O-CG 3.49Å; R278-E282 PolarHBondContact O-N 3.43Å
279K86.1Confident92.3Very high105 Ų10553.4 Ų53.446%0.45727%0.272SS..Hα-helixtrans-56-42.9176.6-176.1175.6-177174.90111.9A275 P276 L277 Q283A275-K279 WeakPolarHBondContact O-CB 3.23Å; A275-K279 PolarHBondContact O-N 2.68Å; P276-K279 PolarHBondContact O-N 3.07Å; L277-K279 VanDerWaalsContact C-N 3.34Å; L277-K279 PolarHBondContact O-N 2.93Å; K279-Q283 WeakPolarHBondContact O-CB 3.47Å; K279-Q283 WeakPolarHBondContact O-CG 3.15Å; K279-Q283 PolarHBondContact O-N 3.06Å; K279-Q283 VanDerWaalsContact O-N 3.12Å
280R89.2Confident92.3Very high16 Ų1653.8 Ų53.86%0.0627%0.274CS..Hα-helixtrans-72.5-30.9178.1-61.9-36.7179.7167.25.1112.9L249 G250 G251 P276 L277 R278 G284 W285 V286L249-R280 HydrophobicContact CB-CG 4.04Å; L249-R280 HydrophobicContact CD2-CG 4.23Å; L249-R280 PolarHBondContact O-NE 3.26Å; L249-R280 VanDerWaalsContact O-NE 3.15Å; G250-R280 PolarHBondContact O-NH2 3.33Å; G251-R280 PolarHBondContact O-NH2 3.25Å; P276-R280 VanDerWaalsContact O-CG 3.31Å; P276-R280 WeakPolarHBondContact O-CG 3.36Å; P276-R280 PolarHBondContact O-N 2.95Å; L277-R280 PolarHBondContact O-N 3.09Å; R278-R280 VanDerWaalsContact C-N 3.3Å; R278-R280 PolarHBondContact O-N 2.79Å; R280-G284 PolarHBondContact O-N 3.29Å; R280-W285 HydrophobicContact CB-CB 4.31Å; R280-W285 WeakPolarHBondContact O-CB 3.41Å; R280-W285 PolarHBondContact O-N 2.69Å; R280-V286 HydrophobicContact CB-CB 4.41Å; R280-V286 HydrophobicContact CB-CG2 3.79Å; R280-V286 PolarHBondContact O-N 3.44Å; R280-V286 VanDerWaalsContact O-N 3.13Å
281H93.4Very high92.2Very high85 Ų8558 Ų5839%0.39430%0.303SS..Hα-helixtrans-68-47.6173.5-175.253000111.8L277 R278 Q283 G284 V286 M287 V289L277-H281 PolarHBondContact O-N 3.31Å; R278-H281 WeakPolarHBondContact O-CB 3.28Å; R278-H281 PolarHBondContact O-N 3.47Å; R278-H281 VanDerWaalsContact O-N 3.08Å; H281-Q283 PolarHBondContact O-N 3.45Å; H281-G284 WeakPolarHBondContact O-CA 3.18Å; H281-G284 PolarHBondContact O-N 2.9Å; H281-V286 WeakPolarHBondContact CA-O 3.48Å; H281-V286 HydrophobicContact CB-CB 4.36Å; H281-V286 PolarHBondContact ND1-O 2.94Å; H281-M287 PolarHBondContact CE1-O 2.72Å; H281-V289 HydrophobicContact CB-CG2 4.06Å
282E89.8Confident92.3Very high156 Ų15658.3 Ų58.373%0.72931%0.308SS*.Hα-helixtrans-60.1-32.6176-70.7168.3-172.300112.5R278 G284R278-E282 WeakPolarHBondContact O-CG 3.49Å; R278-E282 PolarHBondContact O-N 3.43Å; E282-G284 PolarHBondContact O-N 3.21Å
283Q84.6Confident92.4Very high78 Ų7858.5 Ų58.536%0.36431%0.308SS..THydrogen-bonded Turntrans-72.9-9.5173.4-72.9171-8.100113.9K279 H281 W285K279-Q283 WeakPolarHBondContact O-CB 3.47Å; K279-Q283 WeakPolarHBondContact O-CG 3.15Å; K279-Q283 PolarHBondContact O-N 3.06Å; K279-Q283 VanDerWaalsContact O-N 3.12Å; H281-Q283 PolarHBondContact O-N 3.45Å; Q283-W285 VanDerWaalsContact C-N 3.29Å; Q283-W285 HydrophobicContact CB-CG 4.05Å; Q283-W285 VanDerWaalsContact O-CD1 3.29Å; Q283-W285 PolarHBondContact O-N 3.33Å
284G88.8Confident92.8Very high35 Ų3562.2 Ų62.236%0.36132%0.324SS..THydrogen-bonded Turntrans69.326.8-173.400000113.3K258 R280 H281 E282K258-G284 PolarHBondContact NZ-O 2.79Å; R280-G284 PolarHBondContact O-N 3.29Å; H281-G284 WeakPolarHBondContact O-CA 3.18Å; H281-G284 PolarHBondContact O-N 2.9Å; E282-G284 PolarHBondContact O-N 3.21Å
285W91Very high93.1Very high15 Ų1564 Ų646%0.05733%0.332CS..SBendtrans-91.3-43.6176-69.822.1000110.9P215 V219 G254 A255 A257 K258 R280 Q283 S311 M502P215-W285 HydrophobicContact CB-CH2 3.31Å; P215-W285 HydrophobicContact CB-CZ2 4.36Å; P215-W285 HydrophobicContact CB-CZ3 3.72Å; P215-W285 HydrophobicContact CG-CH2 3.09Å; P215-W285 HydrophobicContact CG-CZ2 3.68Å; P215-W285 HydrophobicContact CG-CZ3 3.86Å; V219-W285 HydrophobicContact CG2-CH2 3.78Å; V219-W285 HydrophobicContact CG2-CZ2 4.44Å; V219-W285 HydrophobicContact CG2-CZ3 4.19Å; G254-W285 VanDerWaalsContact O-CE3 3.32Å; A255-W285 HydrophobicContact CB-CZ3 4.13Å; A257-W285 WeakPolarHBondContact CB-O 3.31Å; K258-W285 HydrophobicContact CB-CG 4.46Å; R280-W285 HydrophobicContact CB-CB 4.31Å; R280-W285 WeakPolarHBondContact O-CB 3.41Å; R280-W285 PolarHBondContact O-N 2.69Å; Q283-W285 VanDerWaalsContact C-N 3.29Å; Q283-W285 HydrophobicContact CB-CG 4.05Å; Q283-W285 VanDerWaalsContact O-CD1 3.29Å; Q283-W285 PolarHBondContact O-N 3.33Å; W285-S311 WeakPolarHBondContact O-CB 3.5Å; W285-S311 PolarHBondContact O-OG 3.48Å; W285-M502 HydrophobicContact CZ2-CG 4.37Å
286V95.8Very high93.6Very high0 Ų061 Ų610%031%0.308CS..SBendtrans-93.4119.4166.1172.30000107.7L249 A257 R280 H281 E288 V289 S311L249-V286 HydrophobicContact CD1-CG2 3.99Å; L249-V286 HydrophobicContact CD2-CG2 3.87Å; A257-V286 HydrophobicContact CB-CG2 3.77Å; R280-V286 HydrophobicContact CB-CB 4.41Å; R280-V286 HydrophobicContact CB-CG2 3.79Å; R280-V286 PolarHBondContact O-N 3.44Å; R280-V286 VanDerWaalsContact O-N 3.13Å; H281-V286 WeakPolarHBondContact CA-O 3.48Å; H281-V286 HydrophobicContact CB-CB 4.36Å; H281-V286 PolarHBondContact ND1-O 2.94Å; V286-E288 WeakPolarHBondContact CG1-O 3.44Å; V286-V289 HydrophobicContact CG1-CG2 3.85Å; V286-S311 WeakPolarHBondContact CA-OG 3.34Å
287M96.9Very high94.3Very high89 Ų8960 Ų6044%0.43830%0.301SS..  trans-78.8-40-177.8-70.2170.964.800111.9V261 H281 L310 S311V261-M287 HydrophobicContact CG1-SD 4.42Å; V261-M287 HydrophobicContact CG2-SD 3.82Å; H281-M287 PolarHBondContact CE1-O 2.72Å; M287-L310 HydrophobicContact CB-CD1 4.15Å; M287-S311 WeakPolarHBondContact CG-OG 2.9Å; M287-S311 PolarHBondContact N-O 3.49Å; M287-S311 PolarHBondContact N-OG 3.03Å
288E98.1Very high94.6Very high68 Ų6866 Ų6632%0.31833%0.327SS..EExtended strand (participates in β ladder)trans-135.5150.2-176.4-66.6177.6-149.400110.4V286 R299 L310 S311 L312 G313V286-E288 WeakPolarHBondContact CG1-O 3.44Å; E288-R299 VanDerWaalsContact CD-NE 3.32Å; E288-R299 IonicContact OE1-CZ 3.36Å; E288-R299 IonicContact OE1-NE 3.29Å; E288-R299 PolarHBondContact OE1-NE 3.24Å; E288-R299 VanDerWaalsContact OE1-NE 3.14Å; E288-R299 IonicContact OE1-NH2 2.72Å; E288-R299 PolarHBondContact OE1-NH2 3.15Å; E288-R299 WeakPolarHBondContact OE2-CD 3.35Å; E288-R299 IonicContact OE2-CZ 3.69Å; E288-R299 IonicContact OE2-NE 3.49Å; E288-R299 PolarHBondContact OE2-NE 3.15Å; E288-R299 IonicContact OE2-NH2 3.82Å; E288-L310 HydrophobicContact CB-CD1 4.34Å; E288-L310 HydrophobicContact CG-CD1 4.03Å; E288-L310 WeakPolarHBondContact OE1-CD1 3.42Å; E288-S311 PolarHBondContact N-O 3.27Å; E288-L312 HydrophobicContact CB-CD1 3.75Å; E288-L312 WeakPolarHBondContact O-CA 3.46Å; E288-G313 PolarHBondContact O-N 2.89Å
289V98.3Very high94.9Very high63 Ų6361.6 Ų61.638%0.38231%0.31SS..EExtended strand (participates in β ladder)trans-127.8137.7178.9172.70000109.4L277 H281 V286 G313L277-V289 HydrophobicContact CD1-CG1 4.49Å; L277-V289 HydrophobicContact CD2-CB 4.25Å; L277-V289 HydrophobicContact CD2-CG1 3.55Å; L277-V289 HydrophobicContact CD2-CG2 3.64Å; H281-V289 HydrophobicContact CB-CG2 4.06Å; V286-V289 HydrophobicContact CG1-CG2 3.85Å; V289-G313 WeakPolarHBondContact CA-O 3.42Å
290T98.1Very high95.5Very high10 Ų1056.6 Ų56.66%0.06129%0.288CS..EExtended strand (participates in β ladder)trans-140.4148.3169.3-173.80000110.9S292 Q295 C296 L312 G313 Y314 H315T290-S292 PolarHBondContact OG1-N 3.5Å; T290-S292 VanDerWaalsContact OG1-N 3.17Å; T290-S292 PolarHBondContact OG1-O 2.82Å; T290-Q295 WeakPolarHBondContact OG1-CB 3.3Å; T290-Q295 PolarHBondContact OG1-OE1 2.85Å; T290-C296 HydrophobicContact CG2-CB 3.84Å; T290-L312 HydrophobicContact CG2-CD1 4.07Å; T290-L312 HydrophobicContact CG2-CD2 4.47Å; T290-L312 HydrophobicContact CG2-CG 4.42Å; T290-G313 PolarHBondContact N-O 3.04Å; T290-Y314 CarbonylContact O-C 3.59Å; T290-Y314 WeakPolarHBondContact O-CA 3.28Å; T290-H315 PolarHBondContact O-N 3.32Å
291S97.4Very high95.9Very high91 Ų9159.1 Ų59.164%0.63630%0.298SS*.SBendtrans-110.48.5169.8630000112.2
292S98.1Very high96.1Very high29 Ų2959.3 Ų59.320%0.20330%0.299CS..  trans-111.3124.5176.9160.90000109.7T290 E294 Q295 C296T290-S292 PolarHBondContact OG1-N 3.5Å; T290-S292 VanDerWaalsContact OG1-N 3.17Å; T290-S292 PolarHBondContact OG1-O 2.82Å; S292-E294 VanDerWaalsContact C-N 3.28Å; S292-E294 PolarHBondContact O-N 3.38Å; S292-E294 PolarHBondContact OG-N 3.07Å; S292-E294 PolarHBondContact OG-OE2 3.37Å; S292-Q295 PolarHBondContact O-N 2.84Å; S292-Q295 PolarHBondContact OG-N 3.14Å; S292-C296 WeakPolarHBondContact O-CB 3.44Å; S292-C296 PolarHBondContact O-N 2.92Å
293L98.1Very high96.5Very high33 Ų3351.9 Ų51.917%0.17326%0.264CS..Hα-helixtrans-62-36.9174.3-75.9170.2000111.6C296 I297 Y314 D320 L321 R324L293-C296 WeakPolarHBondContact O-CB 3.41Å; L293-C296 PolarHBondContact O-N 3.22Å; L293-I297 VanDerWaalsContact O-CG1 3.31Å; L293-I297 WeakPolarHBondContact O-CG1 3.18Å; L293-I297 PolarHBondContact O-N 3.06Å; L293-Y314 HydrophobicContact CD2-CD1 4.46Å; L293-Y314 HydrophobicContact CD2-CD2 4.46Å; L293-Y314 HydrophobicContact CD2-CE1 3.79Å; L293-Y314 HydrophobicContact CD2-CE2 3.79Å; L293-Y314 VanDerWaalsContact CD2-CZ 3.41Å; L293-Y314 WeakPolarHBondContact CD2-OH 3.5Å; L293-Y314 HydrophobicContact CG-CE2 3.97Å; L293-Y314 WeakPolarHBondContact CG-OH 3.32Å; L293-D320 HydrophobicContact CD1-CB 4.23Å; L293-L321 HydrophobicContact CD2-CB 4.37Å; L293-L321 HydrophobicContact CD2-CD1 4.13Å; L293-R324 HydrophobicContact CB-CG 3.96Å; L293-R324 HydrophobicContact CD1-CB 4.15Å; L293-R324 HydrophobicContact CD1-CG 4.3Å; L293-R324 HydrophobicContact CD2-CB 4.03Å; L293-R324 HydrophobicContact CD2-CG 4.11Å; L293-R324 HydrophobicContact CG-CG 4.35Å
294E97.9Very high97.1Very high122 Ų12251.8 Ų51.857%0.5726%0.261SS*.Hα-helixtrans-61.6-46.7176.3-62.470.2-151.600111.5S292 C296 I297 K298S292-E294 VanDerWaalsContact C-N 3.28Å; S292-E294 PolarHBondContact O-N 3.38Å; S292-E294 PolarHBondContact OG-N 3.07Å; S292-E294 PolarHBondContact OG-OE2 3.37Å; E294-C296 VanDerWaalsContact C-N 3.34Å; E294-I297 PolarHBondContact O-N 3.23Å; E294-K298 WeakPolarHBondContact O-CB 3.37Å; E294-K298 PolarHBondContact O-N 3.26Å
295Q98.1Very high97.5Very high120 Ų12055.8 Ų55.856%0.56128%0.278SS*.Hα-helixtrans-65.5-39.3175.9-69.5-177.7-5.800111.5T290 S292 K298 R299T290-Q295 WeakPolarHBondContact OG1-CB 3.3Å; T290-Q295 PolarHBondContact OG1-OE1 2.85Å; S292-Q295 PolarHBondContact O-N 2.84Å; S292-Q295 PolarHBondContact OG-N 3.14Å; Q295-K298 PolarHBondContact O-N 3.15Å; Q295-R299 WeakPolarHBondContact O-CB 3.44Å; Q295-R299 PolarHBondContact O-N 2.76Å
296C98.1Very high97.8Very high0 Ų058.3 Ų58.30%030%0.298CS..Hα-helixtrans-57.5-52.6175.7-1710000111.1T290 S292 L293 E294 K298 R299 I300T290-C296 HydrophobicContact CG2-CB 3.84Å; S292-C296 WeakPolarHBondContact O-CB 3.44Å; S292-C296 PolarHBondContact O-N 2.92Å; L293-C296 WeakPolarHBondContact O-CB 3.41Å; L293-C296 PolarHBondContact O-N 3.22Å; E294-C296 VanDerWaalsContact C-N 3.34Å; C296-K298 PolarHBondContact O-N 2.71Å; C296-R299 PolarHBondContact O-N 3.18Å; C296-I300 VanDerWaalsContact O-CG1 3.28Å; C296-I300 WeakPolarHBondContact O-CG1 3.5Å; C296-I300 PolarHBondContact O-N 2.8Å
297I98.4Very high97.9Very high2 Ų264.2 Ų64.21%0.0132%0.324CS..Hα-helixtrans-60.1-44.2177.4-66.9-52.7000111.8L293 E294 R299 I300 R301 R324 L325 E328 L336L293-I297 VanDerWaalsContact O-CG1 3.31Å; L293-I297 WeakPolarHBondContact O-CG1 3.18Å; L293-I297 PolarHBondContact O-N 3.06Å; E294-I297 PolarHBondContact O-N 3.23Å; I297-R299 VanDerWaalsContact C-N 3.33Å; I297-R299 PolarHBondContact O-N 2.82Å; I297-I300 HydrophobicContact CD1-CD1 4.3Å; I297-I300 PolarHBondContact O-N 3.47Å; I297-R301 VanDerWaalsContact CG2-NH1 3.3Å; I297-R301 PolarHBondContact O-N 2.97Å; I297-R324 HydrophobicContact CD1-CG 4.17Å; I297-R324 HydrophobicContact CG1-CG 3.92Å; I297-L325 HydrophobicContact CD1-CD2 3.65Å; I297-L325 HydrophobicContact CD1-CG 4.28Å; I297-E328 HydrophobicContact CD1-CG 4.29Å; I297-E328 HydrophobicContact CG1-CG 4.2Å; I297-E328 HydrophobicContact CG2-CG 3.77Å; I297-L336 HydrophobicContact CD1-CD1 4.05Å; I297-L336 HydrophobicContact CG2-CD1 3.82Å
298K98.3Very high97.9Very high128 Ų12862.9 Ų62.956%0.55732%0.321SS*.Hα-helixtrans-58-47.5176.6-179.6-177.6171.1-174.30111E294 Q295 C296 I300 R301 E302E294-K298 WeakPolarHBondContact O-CB 3.37Å; E294-K298 PolarHBondContact O-N 3.26Å; Q295-K298 PolarHBondContact O-N 3.15Å; C296-K298 PolarHBondContact O-N 2.71Å; K298-I300 PolarHBondContact O-N 3.11Å; K298-R301 PolarHBondContact O-N 3.33Å; K298-E302 WeakPolarHBondContact CE-OE1 3.5Å; K298-E302 IonicContact NZ-OE1 2.8Å; K298-E302 WeakPolarHBondContact O-CG 3.21Å; K298-E302 PolarHBondContact O-N 2.74Å; K298-E302 VanDerWaalsContact O-N 3.11Å
299R98.1Very high97.8Very high48 Ų4861.7 Ų61.718%0.18132%0.319CS..Hα-helixtrans-67.1-36.4-177-171.863.9-175.996.5-0.2112.5E288 Q295 C296 I297 E302 A303 L310 L312E288-R299 VanDerWaalsContact CD-NE 3.32Å; E288-R299 IonicContact OE1-CZ 3.36Å; E288-R299 IonicContact OE1-NE 3.29Å; E288-R299 PolarHBondContact OE1-NE 3.24Å; E288-R299 VanDerWaalsContact OE1-NE 3.14Å; E288-R299 IonicContact OE1-NH2 2.72Å; E288-R299 PolarHBondContact OE1-NH2 3.15Å; E288-R299 WeakPolarHBondContact OE2-CD 3.35Å; E288-R299 IonicContact OE2-CZ 3.69Å; E288-R299 IonicContact OE2-NE 3.49Å; E288-R299 PolarHBondContact OE2-NE 3.15Å; E288-R299 IonicContact OE2-NH2 3.82Å; Q295-R299 WeakPolarHBondContact O-CB 3.44Å; Q295-R299 PolarHBondContact O-N 2.76Å; C296-R299 PolarHBondContact O-N 3.18Å; I297-R299 VanDerWaalsContact C-N 3.33Å; I297-R299 PolarHBondContact O-N 2.82Å; R299-E302 PolarHBondContact O-N 3.01Å; R299-A303 WeakPolarHBondContact O-CB 3.38Å; R299-A303 PolarHBondContact O-N 2.96Å; R299-L310 HydrophobicContact CG-CD2 3.78Å; R299-L312 HydrophobicContact CB-CD2 4.03Å; R299-L312 HydrophobicContact CG-CD1 4.46Å; R299-L312 HydrophobicContact CG-CD2 4.07Å
300I98.3Very high97.8Very high0 Ų058.7 Ų58.70%030%0.301CS..Hα-helixtrans-56.2-51.6171.8-69.7166000110.2V243 V268 C296 I297 K298 E302 A303 R304 L325 L336V243-I300 HydrophobicContact CG1-CG2 4.03Å; V243-I300 HydrophobicContact CG2-CG2 3.88Å; V268-I300 HydrophobicContact CG2-CD1 3.82Å; V268-I300 HydrophobicContact CG2-CG1 3.67Å; C296-I300 VanDerWaalsContact O-CG1 3.28Å; C296-I300 WeakPolarHBondContact O-CG1 3.5Å; C296-I300 PolarHBondContact O-N 2.8Å; I297-I300 HydrophobicContact CD1-CD1 4.3Å; I297-I300 PolarHBondContact O-N 3.47Å; K298-I300 PolarHBondContact O-N 3.11Å; I300-E302 PolarHBondContact O-N 2.86Å; I300-A303 PolarHBondContact O-N 3.17Å; I300-R304 WeakPolarHBondContact O-CB 3.5Å; I300-R304 PolarHBondContact O-N 3.15Å; I300-L325 HydrophobicContact CD1-CD2 4.41Å; I300-L336 HydrophobicContact CG2-CB 4.41Å; I300-L336 HydrophobicContact CG2-CD2 4.48Å
301R98.1Very high97.8Very high69 Ų6958.2 Ų58.226%0.2630%0.298SS..Hα-helixtrans-58.9-44.1179.5-73178.5171.5125.53112.7I297 K298 T305 E328 E334 L336I297-R301 VanDerWaalsContact CG2-NH1 3.3Å; I297-R301 PolarHBondContact O-N 2.97Å; K298-R301 PolarHBondContact O-N 3.33Å; R301-T305 WeakPolarHBondContact O-CB 3.36Å; R301-T305 PolarHBondContact O-N 3.35Å; R301-T305 PolarHBondContact O-OG1 3.42Å; R301-E328 IonicContact CZ-OE2 3.36Å; R301-E328 IonicContact NH1-OE2 2.84Å; R301-E328 PolarHBondContact NH1-OE2 3Å; R301-E328 VanDerWaalsContact NH1-OE2 3.07Å; R301-E328 IonicContact NH2-OE2 3.04Å; R301-E328 PolarHBondContact NH2-OE2 3.44Å; R301-E334 IonicContact CZ-OE2 3.81Å; R301-E334 IonicContact NE-OE1 2.72Å; R301-E334 IonicContact NE-OE2 3.77Å; R301-E334 PolarHBondContact NE-OE2 3.4Å; R301-E334 IonicContact NH2-OE2 2.61Å; R301-E334 PolarHBondContact NH2-OE2 3.3Å; R301-L336 HydrophobicContact CG-CD2 3.66Å
302E98.3Very high97.8Very high90 Ų9054 Ų5442%0.42127%0.268SS..Hα-helixtrans-64.4-46.4178.6-70.7171.6171.500112.1K298 R299 I300 T305 S306K298-E302 WeakPolarHBondContact CE-OE1 3.5Å; K298-E302 IonicContact NZ-OE1 2.8Å; K298-E302 WeakPolarHBondContact O-CG 3.21Å; K298-E302 PolarHBondContact O-N 2.74Å; K298-E302 VanDerWaalsContact O-N 3.11Å; R299-E302 PolarHBondContact O-N 3.01Å; I300-E302 PolarHBondContact O-N 2.86Å; E302-T305 PolarHBondContact O-N 3.01Å; E302-S306 WeakPolarHBondContact O-CB 3.37Å; E302-S306 PolarHBondContact O-N 2.64Å; E302-S306 PolarHBondContact O-OG 2.97Å
303A97.9Very high97.8Very high0 Ų052.7 Ų52.70%026%0.259CS..Hα-helixtrans-64.7-41.8178.500000111.7V266 R299 I300 S306 K307 T308 L310V266-A303 HydrophobicContact CB-CB 4.37Å; V266-A303 HydrophobicContact CG1-CB 3.82Å; V266-A303 HydrophobicContact CG2-CB 3.56Å; R299-A303 WeakPolarHBondContact O-CB 3.38Å; R299-A303 PolarHBondContact O-N 2.96Å; I300-A303 PolarHBondContact O-N 3.17Å; A303-S306 PolarHBondContact O-OG 3.45Å; A303-K307 WeakPolarHBondContact O-CA 3.43Å; A303-K307 PolarHBondContact O-N 3.07Å; A303-T308 PolarHBondContact O-N 2.75Å; A303-T308 VanDerWaalsContact O-N 3.15Å; A303-L310 HydrophobicContact CB-CB 4.33Å; A303-L310 HydrophobicContact CB-CD2 3.88Å
304R97.3Very high97.8Very high76 Ų7651.8 Ų51.829%0.28725%0.253SS..Hα-helixtrans-59.4-50.1176.3-166.3-167.6-179-172.27.4111.3G241 V243 I300 K307 E334 L335G241-R304 WeakPolarHBondContact O-CG 3.46Å; V243-R304 HydrophobicContact CG2-CB 4.4Å; V243-R304 HydrophobicContact CG2-CG 4.28Å; I300-R304 WeakPolarHBondContact O-CB 3.5Å; I300-R304 PolarHBondContact O-N 3.15Å; R304-K307 PolarHBondContact O-N 2.53Å; R304-E334 IonicContact NH1-OE1 3.9Å; R304-L335 PolarHBondContact NH1-O 3.34Å
305T97.4Very high97.9Very high119 Ų11949 Ų4973%0.7324%0.24SC*.Hα-helixtrans-66.7-43.6-178-560000111.9R301 E302 K307R301-T305 WeakPolarHBondContact O-CB 3.36Å; R301-T305 PolarHBondContact O-N 3.35Å; R301-T305 PolarHBondContact O-OG1 3.42Å; E302-T305 PolarHBondContact O-N 3.01Å; T305-K307 PolarHBondContact O-N 3.32Å
306S97.6Very high97.8Very high67 Ų6744 Ų4447%0.46922%0.22SC..Hα-helixtrans-77.6-7.1178.661.50000113.9E302 A303 T308E302-S306 WeakPolarHBondContact O-CB 3.37Å; E302-S306 PolarHBondContact O-N 2.64Å; E302-S306 PolarHBondContact O-OG 2.97Å; A303-S306 PolarHBondContact O-OG 3.45Å; S306-T308 WeakPolarHBondContact CB-OG1 3.47Å; S306-T308 PolarHBondContact O-N 3.38Å; S306-T308 PolarHBondContact OG-OG1 3.17Å
307K97.7Very high97.9Very high125 Ų12544.5 Ų44.554%0.54322%0.223SC..THydrogen-bonded Turntrans54.831.6-175.5-65.9-172.4178.8-174.80113.2R240 A303 R304 T305R240-K307 HydrophobicContact CB-CB 4.13Å; A303-K307 WeakPolarHBondContact O-CA 3.43Å; A303-K307 PolarHBondContact O-N 3.07Å; R304-K307 PolarHBondContact O-N 2.53Å; T305-K307 PolarHBondContact O-N 3.32Å
308T96.4Very high97.9Very high61 Ų6144.8 Ų44.837%0.37423%0.225SC..  trans-90.5121-177.5-55.10000109.7A303 S306 L310A303-T308 PolarHBondContact O-N 2.75Å; A303-T308 VanDerWaalsContact O-N 3.15Å; S306-T308 WeakPolarHBondContact CB-OG1 3.47Å; S306-T308 PolarHBondContact O-N 3.38Å; S306-T308 PolarHBondContact OG-OG1 3.17Å; T308-L310 PolarHBondContact O-N 3.45Å
309P96.3Very high97.9Very high43 Ų4338.7 Ų38.728%0.27920%0.198SC..  trans-57.6133.6171-21.832.8000110.5V261 C265V261-P309 HydrophobicContact CG1-CB 4.34Å; C265-P309 WeakPolarHBondContact O-CA 3.5Å
310L97.6Very high97.9Very high0 Ų039 Ų390%020%0.204CC..EExtended strand (participates in β ladder)trans-146141.6-174.5173.665.1000109.7C265 V266 G267 M287 E288 R299 A303 T308 L312C265-L310 PolarHBondContact O-N 3.34Å; V266-L310 CarbonylContact C-O 3.4Å; V266-L310 HydrophobicContact CG1-CB 4.33Å; V266-L310 HydrophobicContact CG1-CD2 4.36Å; G267-L310 PolarHBondContact N-O 2.79Å; M287-L310 HydrophobicContact CB-CD1 4.15Å; E288-L310 HydrophobicContact CB-CD1 4.34Å; E288-L310 HydrophobicContact CG-CD1 4.03Å; E288-L310 WeakPolarHBondContact OE1-CD1 3.42Å; R299-L310 HydrophobicContact CG-CD2 3.78Å; A303-L310 HydrophobicContact CB-CB 4.33Å; A303-L310 HydrophobicContact CB-CD2 3.88Å; T308-L310 PolarHBondContact O-N 3.45Å; L310-L312 HydrophobicContact CD2-CB 4.11Å; L310-L312 HydrophobicContact CG-CB 4.26Å
311S97.8Very high97.9Very high0 Ų039 Ų390%020%0.204CC..EExtended strand (participates in β ladder)trans-114.9108.1160.455.50000110.5A257 G267 W285 V286 M287 E288A257-S311 VanDerWaalsContact O-CB 3.27Å; A257-S311 WeakPolarHBondContact O-CB 3.28Å; G267-S311 WeakPolarHBondContact O-CA 3.42Å; W285-S311 WeakPolarHBondContact O-CB 3.5Å; W285-S311 PolarHBondContact O-OG 3.48Å; V286-S311 WeakPolarHBondContact CA-OG 3.34Å; M287-S311 WeakPolarHBondContact CG-OG 2.9Å; M287-S311 PolarHBondContact N-O 3.49Å; M287-S311 PolarHBondContact N-OG 3.03Å; E288-S311 PolarHBondContact N-O 3.27Å
312L98.5Very high98Very high3 Ų335.7 Ų35.72%0.01619%0.191CC..EExtended strand (participates in β ladder)trans-104.1115.7-179.2-178.563.7000110G267 V268 I269 E288 T290 R299 L310G267-L312 PolarHBondContact O-N 3.36Å; V268-L312 WeakPolarHBondContact CA-O 3.44Å; I269-L312 PolarHBondContact N-O 3.45Å; E288-L312 HydrophobicContact CB-CD1 3.75Å; E288-L312 WeakPolarHBondContact O-CA 3.46Å; T290-L312 HydrophobicContact CG2-CD1 4.07Å; T290-L312 HydrophobicContact CG2-CD2 4.47Å; T290-L312 HydrophobicContact CG2-CG 4.42Å; R299-L312 HydrophobicContact CB-CD2 4.03Å; R299-L312 HydrophobicContact CG-CD1 4.46Å; R299-L312 HydrophobicContact CG-CD2 4.07Å; L310-L312 HydrophobicContact CD2-CB 4.11Å; L310-L312 HydrophobicContact CG-CB 4.26Å
313G98.4Very high98Very high0 Ų034.2 Ų34.20%019%0.185CC..EExtended strand (participates in β ladder)trans-85.3120.5171.400000110.8I269 E288 V289 T290I269-G313 WeakPolarHBondContact O-CA 3.2Å; E288-G313 PolarHBondContact O-N 2.89Å; V289-G313 WeakPolarHBondContact CA-O 3.42Å; T290-G313 PolarHBondContact N-O 3.04Å
314Y98.6Very high98Very high14 Ų1436 Ų366%0.05519%0.191CC..EExtended strand (participates in β ladder)trans-96.6114.6170.8170.6-121.1000109.5I269 A270 E271 T290 L293 G316 L321I269-Y314 PolarHBondContact O-N 3.25Å; A270-Y314 WeakPolarHBondContact CA-O 3.29Å; A270-Y314 HydrophobicContact CB-CD1 3.91Å; E271-Y314 PolarHBondContact N-O 3.09Å; T290-Y314 CarbonylContact O-C 3.59Å; T290-Y314 WeakPolarHBondContact O-CA 3.28Å; L293-Y314 HydrophobicContact CD2-CD1 4.46Å; L293-Y314 HydrophobicContact CD2-CD2 4.46Å; L293-Y314 HydrophobicContact CD2-CE1 3.79Å; L293-Y314 HydrophobicContact CD2-CE2 3.79Å; L293-Y314 VanDerWaalsContact CD2-CZ 3.41Å; L293-Y314 WeakPolarHBondContact CD2-OH 3.5Å; L293-Y314 HydrophobicContact CG-CE2 3.97Å; L293-Y314 WeakPolarHBondContact CG-OH 3.32Å; Y314-G316 PolarHBondContact O-N 3.19Å; Y314-L321 HydrophobicContact CD1-CB 4.04Å; Y314-L321 HydrophobicContact CD1-CD2 4.37Å; Y314-L321 HydrophobicContact CE1-CB 4.12Å
315H98.3Very high98.1Very high63 Ų6332.5 Ų32.529%0.29218%0.178SC..EExtended strand (participates in β ladder)trans-79.695.6173.1-178.5-153.6000109.3E271 L277 T290E271-H315 CarbonylContact O-C 3.58Å; E271-H315 WeakPolarHBondContact O-CA 3.5Å; L277-H315 HydrophobicContact CD1-CB 3.76Å; T290-H315 PolarHBondContact O-N 3.32Å
316G97.7Very high98.1Very high15 Ų1528 Ų2816%0.15515%0.149CC..SBendtrans165.6179.6-175.200000112.1E271 Y314E271-G316 CarbonylContact C-O 3.56Å; E271-G316 PolarHBondContact O-N 3.14Å; Y314-G316 PolarHBondContact O-N 3.19Å
317N98.4Very high98.2Very high12 Ų1229.3 Ų29.36%0.06415%0.151CC..  trans-77.6137.2-178.2-158.5-68.1000111.2V272 V319 D320 L321 Y355 V357V272-N317 HydrophobicContact CG1-CB 4.1Å; N317-V319 PolarHBondContact O-N 3.18Å; N317-V319 WeakPolarHBondContact OD1-CB 3.46Å; N317-V319 WeakPolarHBondContact OD1-CG2 3.27Å; N317-V319 PolarHBondContact OD1-N 2.88Å; N317-D320 WeakPolarHBondContact CB-OD2 3.46Å; N317-D320 WeakPolarHBondContact O-CB 3.44Å; N317-D320 PolarHBondContact O-N 3.12Å; N317-D320 VanDerWaalsContact O-N 3.13Å; N317-L321 PolarHBondContact O-N 3.44Å; N317-Y355 PolarHBondContact ND2-O 3.24Å; N317-V357 HydrophobicContact CB-CB 4.41Å; N317-V357 HydrophobicContact CB-CG2 4.16Å; N317-V357 WeakPolarHBondContact ND2-CA 3.43Å; N317-V357 PolarHBondContact ND2-N 3.4Å
318V98.4Very high98.2Very high7 Ų723.4 Ų23.44%0.04213%0.125CC..Hα-helixtrans-59.1-32.6176.168.10000111.9A270 D320 L321 W322 H386A270-V318 HydrophobicContact CB-CB 3.71Å; A270-V318 HydrophobicContact CB-CG2 4.02Å; V318-D320 VanDerWaalsContact C-N 3.34Å; V318-D320 PolarHBondContact O-N 3.04Å; V318-L321 WeakPolarHBondContact O-CB 3.41Å; V318-L321 PolarHBondContact O-N 3.48Å; V318-L321 VanDerWaalsContact O-N 3.17Å; V318-W322 VanDerWaalsContact O-CD1 3.25Å; V318-W322 PolarHBondContact O-N 3.16Å; V318-H386 VanDerWaalsContact CG1-CE1 3.41Å; V318-H386 WeakPolarHBondContact CG1-CE1 3.23Å
319V98.7Very high98.3Very high0 Ų023.4 Ų23.40%012%0.12CC..Hα-helixtrans-64.5-40.4178.2-177.80000110.9N317 L321 W322 E323 Y354 V357 R385 H386N317-V319 PolarHBondContact O-N 3.18Å; N317-V319 WeakPolarHBondContact OD1-CB 3.46Å; N317-V319 WeakPolarHBondContact OD1-CG2 3.27Å; N317-V319 PolarHBondContact OD1-N 2.88Å; V319-L321 VanDerWaalsContact C-N 3.3Å; V319-L321 PolarHBondContact O-N 2.95Å; V319-W322 PolarHBondContact O-N 3.32Å; V319-E323 HydrophobicContact CG1-CG 4.3Å; V319-E323 WeakPolarHBondContact O-CB 3.3Å; V319-E323 WeakPolarHBondContact O-CG 3.35Å; V319-E323 PolarHBondContact O-N 3.18Å; V319-Y354 WeakPolarHBondContact CG2-OH 3.17Å; V319-V357 HydrophobicContact CB-CB 3.9Å; V319-V357 HydrophobicContact CB-CG1 4.29Å; V319-V357 HydrophobicContact CB-CG2 4.04Å; V319-V357 HydrophobicContact CG1-CB 4.18Å; V319-V357 HydrophobicContact CG1-CG1 4.04Å; V319-V357 HydrophobicContact CG1-CG2 4.25Å; V319-V357 HydrophobicContact CG2-CB 4.38Å; V319-R385 HydrophobicContact CG1-CB 4.03Å; V319-H386 HydrophobicContact CG2-CB 3.72Å
320D98.6Very high98.4Very high54 Ų5427.5 Ų27.529%0.28914%0.136SC..Hα-helixtrans-62.7-39.1174.9-65-43.3000111.2L293 N317 V318 R324 V357L293-D320 HydrophobicContact CD1-CB 4.23Å; N317-D320 WeakPolarHBondContact CB-OD2 3.46Å; N317-D320 WeakPolarHBondContact O-CB 3.44Å; N317-D320 PolarHBondContact O-N 3.12Å; N317-D320 VanDerWaalsContact O-N 3.13Å; V318-D320 VanDerWaalsContact C-N 3.34Å; V318-D320 PolarHBondContact O-N 3.04Å; D320-R324 WeakPolarHBondContact O-CB 3.36Å; D320-R324 PolarHBondContact O-N 3.07Å; D320-V357 WeakPolarHBondContact OD1-CG2 3.49Å
321L98.7Very high98.4Very high0 Ų035.5 Ų35.50%017%0.166CC..Hα-helixtrans-64.6-44.1176.2178.460.3000111.7V245 V268 A270 L293 Y314 N317 V318 V319 R324 L325V245-L321 HydrophobicContact CG1-CD2 3.75Å; V245-L321 HydrophobicContact CG1-CG 4.33Å; V268-L321 HydrophobicContact CG1-CD2 3.8Å; A270-L321 HydrophobicContact CB-CD2 4.14Å; L293-L321 HydrophobicContact CD2-CB 4.37Å; L293-L321 HydrophobicContact CD2-CD1 4.13Å; Y314-L321 HydrophobicContact CD1-CB 4.04Å; Y314-L321 HydrophobicContact CD1-CD2 4.37Å; Y314-L321 HydrophobicContact CE1-CB 4.12Å; N317-L321 PolarHBondContact O-N 3.44Å; V318-L321 WeakPolarHBondContact O-CB 3.41Å; V318-L321 PolarHBondContact O-N 3.48Å; V318-L321 VanDerWaalsContact O-N 3.17Å; V319-L321 VanDerWaalsContact C-N 3.3Å; V319-L321 PolarHBondContact O-N 2.95Å; L321-R324 WeakPolarHBondContact O-CB 3.28Å; L321-R324 PolarHBondContact O-N 2.72Å; L321-L325 HydrophobicContact CD1-CD1 4.28Å; L321-L325 HydrophobicContact CD1-CG 4.38Å; L321-L325 HydrophobicContact CG-CD1 4.15Å; L321-L325 VanDerWaalsContact O-CG 3.29Å; L321-L325 WeakPolarHBondContact O-CG 3.44Å; L321-L325 PolarHBondContact O-N 2.96Å
322W98.8Very high98.3Very high0 Ų038.5 Ų38.50%018%0.184CC..Hα-helixtrans-64.7-47.5176.9-75.7126.6000112.7V245 V318 V319 R324 L325 L326 V337 H386 A389 I390 L393 M398 F400V245-W322 HydrophobicContact CB-CH2 3.67Å; V245-W322 HydrophobicContact CB-CZ2 4.19Å; V245-W322 HydrophobicContact CB-CZ3 4.11Å; V245-W322 HydrophobicContact CG1-CE3 4.48Å; V245-W322 HydrophobicContact CG1-CH2 3.73Å; V245-W322 HydrophobicContact CG1-CZ2 3.84Å; V245-W322 HydrophobicContact CG1-CZ3 4.07Å; V318-W322 VanDerWaalsContact O-CD1 3.25Å; V318-W322 PolarHBondContact O-N 3.16Å; V319-W322 PolarHBondContact O-N 3.32Å; W322-R324 PolarHBondContact O-N 2.89Å; W322-L325 HydrophobicContact CE3-CD1 3.85Å; W322-L325 HydrophobicContact CZ3-CD1 4.02Å; W322-L325 PolarHBondContact O-N 2.6Å; W322-L326 PolarHBondContact O-N 3Å; W322-V337 HydrophobicContact CH2-CG2 4.37Å; W322-V337 HydrophobicContact CZ3-CG1 4.27Å; W322-V337 HydrophobicContact CZ3-CG2 4.19Å; W322-H386 AromaticContact CD1-CD2 3.28Å; W322-H386 AromaticContact CD1-NE2 3.11Å; W322-H386 AromaticContact NE1-CD2 3.61Å; W322-H386 AromaticContact NE1-NE2 3.01Å; W322-H386 PolarHBondContact NE1-NE2 3.43Å; W322-A389 HydrophobicContact CB-CB 3.8Å; W322-I390 HydrophobicContact CD2-CG1 4.24Å; W322-I390 HydrophobicContact CG-CG1 4.45Å; W322-L393 HydrophobicContact CE3-CD1 3.54Å; W322-L393 HydrophobicContact CZ3-CD1 3.99Å; W322-M398 HydrophobicContact CE3-SD 4.43Å; W322-M398 HydrophobicContact CH2-CE 4.38Å; W322-M398 HydrophobicContact CH2-SD 3.7Å; W322-M398 HydrophobicContact CZ3-CE 4.19Å; W322-M398 HydrophobicContact CZ3-SD 3.4Å; W322-M398 WeakPolarHBondContact CZ3-SD 3.49Å; W322-F400 HydrophobicContact CZ2-CD2 4.43Å; W322-F400 HydrophobicContact CZ2-CE2 4.24Å
323E98.7Very high98.3Very high60 Ų6041 Ų4128%0.2821%0.21SC..Hα-helixtrans-61.8-36.4176.4-71.6178.3167.200110.9V319 L326 L327 R385 A389V319-E323 HydrophobicContact CG1-CG 4.3Å; V319-E323 WeakPolarHBondContact O-CB 3.3Å; V319-E323 WeakPolarHBondContact O-CG 3.35Å; V319-E323 PolarHBondContact O-N 3.18Å; E323-L326 PolarHBondContact O-N 3.01Å; E323-L327 WeakPolarHBondContact O-CB 3.4Å; E323-L327 PolarHBondContact O-N 3.16Å; E323-R385 VanDerWaalsContact CD-NH2 3.28Å; E323-R385 IonicContact OE1-CZ 2.83Å; E323-R385 IonicContact OE1-NE 3.21Å; E323-R385 PolarHBondContact OE1-NE 3.24Å; E323-R385 IonicContact OE1-NH2 3.9Å; E323-R385 PolarHBondContact OE1-NH2 3.02Å; E323-R385 IonicContact OE2-CZ 2.75Å; E323-R385 IonicContact OE2-NH2 3.65Å; E323-R385 PolarHBondContact OE2-NH2 3.35Å; E323-A389 HydrophobicContact CG-CB 4.26Å
324R98.5Very high98.2Very high37 Ų3744 Ų4414%0.1422%0.224CC..Hα-helixtrans-65.6-43.1174.3-179.773.1-170.485.6-0.7113.2L293 I297 D320 L321 W322 L326 L327 E328L293-R324 HydrophobicContact CB-CG 3.96Å; L293-R324 HydrophobicContact CD1-CB 4.15Å; L293-R324 HydrophobicContact CD1-CG 4.3Å; L293-R324 HydrophobicContact CD2-CB 4.03Å; L293-R324 HydrophobicContact CD2-CG 4.11Å; L293-R324 HydrophobicContact CG-CG 4.35Å; I297-R324 HydrophobicContact CD1-CG 4.17Å; I297-R324 HydrophobicContact CG1-CG 3.92Å; D320-R324 WeakPolarHBondContact O-CB 3.36Å; D320-R324 PolarHBondContact O-N 3.07Å; L321-R324 WeakPolarHBondContact O-CB 3.28Å; L321-R324 PolarHBondContact O-N 2.72Å; W322-R324 PolarHBondContact O-N 2.89Å; R324-L326 VanDerWaalsContact C-N 3.35Å; R324-L327 PolarHBondContact O-N 3.39Å; R324-E328 IonicContact CZ-OE1 2.78Å; R324-E328 VanDerWaalsContact NH1-CD 3.3Å; R324-E328 IonicContact NH1-OE1 4Å; R324-E328 PolarHBondContact NH1-OE1 3.22Å; R324-E328 VanDerWaalsContact NH2-CD 3.34Å; R324-E328 IonicContact NH2-OE1 3.07Å; R324-E328 PolarHBondContact NH2-OE1 3.37Å; R324-E328 PolarHBondContact O-N 2.88Å
325L98.7Very high98.1Very high3 Ų345.3 Ų45.32%0.01623%0.232CC..Hα-helixtrans-64.3-41.9177-74.9164.4000110.8V245 I297 I300 L321 W322 E328 F329 L336 V337 L393V245-L325 HydrophobicContact CG1-CD1 4.18Å; V245-L325 HydrophobicContact CG2-CD1 3.96Å; I297-L325 HydrophobicContact CD1-CD2 3.65Å; I297-L325 HydrophobicContact CD1-CG 4.28Å; I300-L325 HydrophobicContact CD1-CD2 4.41Å; L321-L325 HydrophobicContact CD1-CD1 4.28Å; L321-L325 HydrophobicContact CD1-CG 4.38Å; L321-L325 HydrophobicContact CG-CD1 4.15Å; L321-L325 VanDerWaalsContact O-CG 3.29Å; L321-L325 WeakPolarHBondContact O-CG 3.44Å; L321-L325 PolarHBondContact O-N 2.96Å; W322-L325 HydrophobicContact CE3-CD1 3.85Å; W322-L325 HydrophobicContact CZ3-CD1 4.02Å; W322-L325 PolarHBondContact O-N 2.6Å; L325-E328 PolarHBondContact O-N 3.28Å; L325-F329 PolarHBondContact O-N 2.96Å; L325-L336 HydrophobicContact CD2-CB 3.97Å; L325-L336 HydrophobicContact CD2-CD1 4.37Å; L325-V337 HydrophobicContact CD1-CG1 4.45Å; L325-L393 HydrophobicContact CB-CD1 4.05Å
326L98.7Very high98.1Very high23 Ų2342.5 Ų42.512%0.1222%0.219CC..Hα-helixtrans-59.9-46172.9177.159.4000111.2W322 E323 R324 E328 F329 E330 A389 K392 L393W322-L326 PolarHBondContact O-N 3Å; E323-L326 PolarHBondContact O-N 3.01Å; R324-L326 VanDerWaalsContact C-N 3.35Å; L326-E328 VanDerWaalsContact C-N 3.34Å; L326-E328 PolarHBondContact O-N 3.46Å; L326-F329 HydrophobicContact CD1-CD1 4.45Å; L326-F329 WeakPolarHBondContact O-CB 3.39Å; L326-F329 PolarHBondContact O-N 3.15Å; L326-F329 VanDerWaalsContact O-N 3.11Å; L326-E330 HydrophobicContact CD1-CG 4.03Å; L326-E330 HydrophobicContact CG-CG 4.38Å; L326-E330 WeakPolarHBondContact O-CG 3.49Å; L326-E330 PolarHBondContact O-N 2.79Å; L326-A389 HydrophobicContact CD2-CB 4.49Å; L326-K392 HydrophobicContact CD1-CB 3.55Å; L326-K392 HydrophobicContact CD1-CG 4.43Å; L326-K392 HydrophobicContact CD2-CB 3.91Å; L326-K392 HydrophobicContact CD2-CG 4.17Å; L326-K392 HydrophobicContact CG-CB 4.39Å; L326-L393 HydrophobicContact CB-CD1 4.46Å; L326-L393 HydrophobicContact CB-CD2 4.39Å; L326-L393 HydrophobicContact CB-CG 4.25Å; L326-L393 HydrophobicContact CD1-CD2 4.45Å; L326-L393 HydrophobicContact CD1-CG 4.43Å
327L98.4Very high98.1Very high95 Ų9541.8 Ų41.850%0.49721%0.212SC..Hα-helixtrans-60.9-39.7177.5-178.166.7000112.6E323 R324 R331E323-L327 WeakPolarHBondContact O-CB 3.4Å; E323-L327 PolarHBondContact O-N 3.16Å; R324-L327 PolarHBondContact O-N 3.39Å; L327-R331 VanDerWaalsContact O-CB 3.24Å; L327-R331 WeakPolarHBondContact O-CB 3.41Å; L327-R331 PolarHBondContact O-N 3.41Å
328E98.2Very high98.1Very high2 Ų242.1 Ų42.11%0.00921%0.214CC..Hα-helixtrans-61.9-44.8172.8-83.7-46.29600111.6I297 R301 R324 L325 L326 R331 T332 L336I297-E328 HydrophobicContact CD1-CG 4.29Å; I297-E328 HydrophobicContact CG1-CG 4.2Å; I297-E328 HydrophobicContact CG2-CG 3.77Å; R301-E328 IonicContact CZ-OE2 3.36Å; R301-E328 IonicContact NH1-OE2 2.84Å; R301-E328 PolarHBondContact NH1-OE2 3Å; R301-E328 VanDerWaalsContact NH1-OE2 3.07Å; R301-E328 IonicContact NH2-OE2 3.04Å; R301-E328 PolarHBondContact NH2-OE2 3.44Å; R324-E328 IonicContact CZ-OE1 2.78Å; R324-E328 VanDerWaalsContact NH1-CD 3.3Å; R324-E328 IonicContact NH1-OE1 4Å; R324-E328 PolarHBondContact NH1-OE1 3.22Å; R324-E328 VanDerWaalsContact NH2-CD 3.34Å; R324-E328 IonicContact NH2-OE1 3.07Å; R324-E328 PolarHBondContact NH2-OE1 3.37Å; R324-E328 PolarHBondContact O-N 2.88Å; L325-E328 PolarHBondContact O-N 3.28Å; L326-E328 VanDerWaalsContact C-N 3.34Å; L326-E328 PolarHBondContact O-N 3.46Å; E328-R331 PolarHBondContact O-N 3.21Å; E328-R331 IonicContact OE1-CZ 3.86Å; E328-R331 IonicContact OE1-NE 3.14Å; E328-R331 IonicContact OE1-NH2 2.73Å; E328-R331 PolarHBondContact OE1-NH2 3.39Å; E328-R331 IonicContact OE2-CZ 3.65Å; E328-R331 IonicContact OE2-NH2 3.35Å; E328-R331 PolarHBondContact OE2-NH2 3.46Å; E328-T332 WeakPolarHBondContact O-CB 3.18Å; E328-T332 PolarHBondContact O-N 3.06Å; E328-T332 PolarHBondContact O-OG1 2.79Å; E328-L336 HydrophobicContact CB-CD1 4.03Å; E328-L336 HydrophobicContact CG-CD1 3.96Å
329F98.3Very high98.1Very high60 Ų6041.9 Ų41.926%0.26321%0.212SC..Hα-helixtrans-61.5-47.5179.1173-108000111.3L325 L326 R331 T332 G333 L335 L393 A396L325-F329 PolarHBondContact O-N 2.96Å; L326-F329 HydrophobicContact CD1-CD1 4.45Å; L326-F329 WeakPolarHBondContact O-CB 3.39Å; L326-F329 PolarHBondContact O-N 3.15Å; L326-F329 VanDerWaalsContact O-N 3.11Å; F329-R331 VanDerWaalsContact C-N 3.3Å; F329-R331 PolarHBondContact O-N 3.04Å; F329-T332 PolarHBondContact O-N 3.2Å; F329-G333 WeakPolarHBondContact O-CA 3.4Å; F329-G333 PolarHBondContact O-N 3.06Å; F329-L335 HydrophobicContact CD2-CB 4.23Å; F329-L335 HydrophobicContact CD2-CD1 4.42Å; F329-L393 HydrophobicContact CB-CD2 4.32Å; F329-A396 HydrophobicContact CD1-CB 4.09Å; F329-A396 HydrophobicContact CD2-CB 4.44Å; F329-A396 HydrophobicContact CE1-CB 3.44Å; F329-A396 VanDerWaalsContact CE1-CB 3.44Å; F329-A396 HydrophobicContact CE2-CB 3.86Å; F329-A396 HydrophobicContact CZ-CB 3.31Å
330E97.9Very high98.1Very high130 Ų13041.9 Ų41.961%0.60721%0.212SC*.Hα-helixtrans-63.2-35.3178.5-70.6178.9157.200112.5L326L326-E330 HydrophobicContact CD1-CG 4.03Å; L326-E330 HydrophobicContact CG-CG 4.38Å; L326-E330 WeakPolarHBondContact O-CG 3.49Å; L326-E330 PolarHBondContact O-N 2.79Å
331R97.6Very high98Very high167 Ų16739.3 Ų39.363%0.6320%0.199SC*.Hα-helixtrans-79.8-34.7-178.6-173.1178.269.8102.32.3113.7L327 E328 F329L327-R331 VanDerWaalsContact O-CB 3.24Å; L327-R331 WeakPolarHBondContact O-CB 3.41Å; L327-R331 PolarHBondContact O-N 3.41Å; E328-R331 PolarHBondContact O-N 3.21Å; E328-R331 IonicContact OE1-CZ 3.86Å; E328-R331 IonicContact OE1-NE 3.14Å; E328-R331 IonicContact OE1-NH2 2.73Å; E328-R331 PolarHBondContact OE1-NH2 3.39Å; E328-R331 IonicContact OE2-CZ 3.65Å; E328-R331 IonicContact OE2-NH2 3.35Å; E328-R331 PolarHBondContact OE2-NH2 3.46Å; F329-R331 VanDerWaalsContact C-N 3.3Å; F329-R331 PolarHBondContact O-N 3.04Å
332T97.1Very high98Very high64 Ų6439.3 Ų39.339%0.39320%0.199SC..Hα-helixtrans-120.7-15.1-167.367.30000114.2E328 F329 E334E328-T332 WeakPolarHBondContact O-CB 3.18Å; E328-T332 PolarHBondContact O-N 3.06Å; E328-T332 PolarHBondContact O-OG1 2.79Å; F329-T332 PolarHBondContact O-N 3.2Å; T332-E334 PolarHBondContact O-N 3.03Å; T332-E334 WeakPolarHBondContact OG1-CB 3.39Å; T332-E334 PolarHBondContact OG1-N 2.92Å
333G96.6Very high97.8Very high55 Ų5540.2 Ų40.257%0.56720%0.203SC*.  trans72.7-1.5-168.600000114F329 L335F329-G333 WeakPolarHBondContact O-CA 3.4Å; F329-G333 PolarHBondContact O-N 3.06Å; G333-L335 PolarHBondContact O-N 3.02Å
334E96.9Very high97.5Very high62 Ų6238.5 Ų38.529%0.2920%0.197SC..  trans-83.4110.2-177.6-170.5-174.7-166.100111.1R301 R304 T332 L336R301-E334 IonicContact CZ-OE2 3.81Å; R301-E334 IonicContact NE-OE1 2.72Å; R301-E334 IonicContact NE-OE2 3.77Å; R301-E334 PolarHBondContact NE-OE2 3.4Å; R301-E334 IonicContact NH2-OE2 2.61Å; R301-E334 PolarHBondContact NH2-OE2 3.3Å; R304-E334 IonicContact NH1-OE1 3.9Å; T332-E334 PolarHBondContact O-N 3.03Å; T332-E334 WeakPolarHBondContact OG1-CB 3.39Å; T332-E334 PolarHBondContact OG1-N 2.92Å; E334-L336 HydrophobicContact CG-CD2 3.89Å; E334-L336 HydrophobicContact CG-CG 4.24Å; E334-L336 PolarHBondContact O-N 3.39Å; E334-L336 WeakPolarHBondContact OE1-CD2 3.33Å
335L97.2Very high97.1Very high42 Ų4238.7 Ų38.722%0.2220%0.204CC..  trans-77.7106.2168.7-17267.9000109.6R304 F329 G333 V337 L393 A396 M398R304-L335 PolarHBondContact NH1-O 3.34Å; F329-L335 HydrophobicContact CD2-CB 4.23Å; F329-L335 HydrophobicContact CD2-CD1 4.42Å; G333-L335 PolarHBondContact O-N 3.02Å; L335-V337 HydrophobicContact CD1-CG1 4.32Å; L335-V337 WeakPolarHBondContact CG-O 3.02Å; L335-L393 HydrophobicContact CD1-CD2 3.99Å; L335-A396 HydrophobicContact CD1-CB 4.29Å; L335-M398 HydrophobicContact CD1-CB 4.46Å
336L97.8Very high96.7Very high4 Ų438.6 Ų38.62%0.02120%0.203CC..  trans-86.1-12.8-175.5-73.2175.2000114.5V243 I297 I300 R301 L325 E328 E334V243-L336 VanDerWaalsContact CB-O 3.26Å; V243-L336 WeakPolarHBondContact CB-O 3.21Å; V243-L336 WeakPolarHBondContact CG1-O 3.35Å; V243-L336 VanDerWaalsContact CG2-O 3.32Å; V243-L336 WeakPolarHBondContact CG2-O 3.24Å; I297-L336 HydrophobicContact CD1-CD1 4.05Å; I297-L336 HydrophobicContact CG2-CD1 3.82Å; I300-L336 HydrophobicContact CG2-CB 4.41Å; I300-L336 HydrophobicContact CG2-CD2 4.48Å; R301-L336 HydrophobicContact CG-CD2 3.66Å; L325-L336 HydrophobicContact CD2-CB 3.97Å; L325-L336 HydrophobicContact CD2-CD1 4.37Å; E328-L336 HydrophobicContact CB-CD1 4.03Å; E328-L336 HydrophobicContact CG-CD1 3.96Å; E334-L336 HydrophobicContact CG-CD2 3.89Å; E334-L336 HydrophobicContact CG-CG 4.24Å; E334-L336 PolarHBondContact O-N 3.39Å; E334-L336 WeakPolarHBondContact OE1-CD2 3.33Å
337V98.2Very high96Very high1 Ų138 Ų381%0.00620%0.199CC..  trans-122.5125.6-174.854.10000109.7V245 W322 L325 L335 L339 M398V245-V337 HydrophobicContact CB-CG2 3.94Å; V245-V337 HydrophobicContact CG2-CB 4.04Å; V245-V337 HydrophobicContact CG2-CG2 3.55Å; W322-V337 HydrophobicContact CH2-CG2 4.37Å; W322-V337 HydrophobicContact CZ3-CG1 4.27Å; W322-V337 HydrophobicContact CZ3-CG2 4.19Å; L325-V337 HydrophobicContact CD1-CG1 4.45Å; L335-V337 HydrophobicContact CD1-CG1 4.32Å; L335-V337 WeakPolarHBondContact CG-O 3.02Å; V337-L339 VanDerWaalsContact CG2-O 3.29Å; V337-L339 WeakPolarHBondContact CG2-O 3.37Å; V337-M398 HydrophobicContact CB-SD 4.35Å; V337-M398 HydrophobicContact CG1-CB 4.39Å; V337-M398 HydrophobicContact CG1-CG 3.98Å; V337-M398 HydrophobicContact CG1-SD 3.59Å; V337-M398 VanDerWaalsContact CG1-SD 3.59Å; V337-M398 HydrophobicContact CG2-CG 4.04Å; V337-M398 HydrophobicContact CG2-SD 3.81Å
338D98.3Very high95.3Very high18 Ų1834.3 Ų34.310%0.09618%0.18CC..SBendtrans-91.5-43176.9-56.2-96.9000110.4L234 R242 V243 F399L234-D338 HydrophobicContact CD1-CB 3.97Å; L234-D338 HydrophobicContact CD2-CB 4.06Å; R242-D338 WeakPolarHBondContact CA-OD2 2.95Å; R242-D338 IonicContact CZ-OD1 3.47Å; R242-D338 IonicContact NH1-OD1 3.28Å; R242-D338 PolarHBondContact NH1-OD1 3.3Å; V243-D338 PolarHBondContact N-OD2 3.16Å; V243-D338 PolarHBondContact O-N 3.35Å; V243-D338 VanDerWaalsContact O-N 3.08Å; D338-F399 PolarHBondContact O-N 3.29Å
339L98.4Very high94.9Very high3 Ų334.2 Ų34.22%0.01618%0.18CC..EExtended strand (participates in β ladder)trans-126.3133.7-172.8-67.1-178.7000110.6A229 L234 V243 F244 V245 V337 F399 W401A229-L339 HydrophobicContact CB-CD1 4.23Å; A229-L339 HydrophobicContact CB-CD2 4.39Å; L234-L339 HydrophobicContact CD1-CD1 4.05Å; L234-L339 HydrophobicContact CD1-CD2 4.18Å; L234-L339 HydrophobicContact CD1-CG 3.95Å; L234-L339 HydrophobicContact CD2-CD2 4.25Å; L234-L339 HydrophobicContact CG-CD2 4.09Å; L234-L339 HydrophobicContact CG-CG 4.42Å; V243-L339 PolarHBondContact O-N 3.4Å; F244-L339 CarbonylContact C-O 3.59Å; F244-L339 VanDerWaalsContact CA-O 3.3Å; F244-L339 WeakPolarHBondContact CA-O 3.35Å; F244-L339 HydrophobicContact CB-CB 4.33Å; F244-L339 HydrophobicContact CD2-CB 3.98Å; V245-L339 PolarHBondContact N-O 3.27Å; V337-L339 VanDerWaalsContact CG2-O 3.29Å; V337-L339 WeakPolarHBondContact CG2-O 3.37Å; L339-F399 CarbonylContact C-O 3.59Å; L339-F399 WeakPolarHBondContact CA-O 3.04Å; L339-F399 HydrophobicContact CD2-CB 4.13Å; L339-F399 HydrophobicContact CD2-CD1 4.42Å; L339-W401 HydrophobicContact CB-CH2 4.14Å; L339-W401 HydrophobicContact CB-CZ3 3.81Å; L339-W401 HydrophobicContact CD2-CZ3 4.09Å; L339-W401 HydrophobicContact CG-CZ3 4.34Å
340G98.1Very high94.4Very high0 Ų033.6 Ų33.60%018%0.176CC..EExtended strand (participates in β ladder)trans-129.9142.9179.300000113.2V245 F399 F400 W401V245-G340 WeakPolarHBondContact O-CA 3.33Å; G340-F399 PolarHBondContact N-O 3.5Å; G340-F400 VanDerWaalsContact C-CD2 3.45Å; G340-F400 VanDerWaalsContact O-CA 3.31Å; G340-F400 WeakPolarHBondContact O-CA 3.48Å; G340-F400 WeakPolarHBondContact O-CD2 3.15Å; G340-W401 WeakPolarHBondContact O-CZ3 3.31Å; G340-W401 PolarHBondContact O-N 3.41Å; G340-W401 VanDerWaalsContact O-N 3.1Å
341S97.8Very high93.6Very high0 Ų031.2 Ų31.20%017%0.168CC..  trans-152.6-176.3169.4-159.10000111.6V245 T246 F400 W401 Y403V245-S341 PolarHBondContact O-N 3.05Å; T246-S341 WeakPolarHBondContact CA-O 3.2Å; S341-F400 VanDerWaalsContact CA-CE2 3.48Å; S341-W401 WeakPolarHBondContact CA-O 3.45Å; S341-W401 WeakPolarHBondContact CB-O 3.49Å; S341-W401 PolarHBondContact OG-NE1 2.88Å; S341-W401 PolarHBondContact OG-O 2.86Å; S341-Y403 WeakPolarHBondContact OG-CD2 3.4Å
342D97.1Very high92.7Very high0 Ų024.4 Ų24.40%015%0.149CC..  trans-144.3136.9174.9-177.9-83.5000110.3S247 T344 H386 F400 Y403 N405 F407S247-D342 WeakPolarHBondContact CB-OD2 3.4Å; S247-D342 WeakPolarHBondContact OG-CA 3.28Å; S247-D342 PolarHBondContact OG-OD2 2.88Å; D342-T344 PolarHBondContact OD1-N 2.79Å; D342-T344 PolarHBondContact OD1-OG1 3.39Å; D342-T344 PolarHBondContact OD2-OG1 2.87Å; D342-H386 IonicContact OD2-CE1 3.93Å; D342-H386 PolarHBondContact OD2-CE1 3.44Å; D342-F400 HydrophobicContact CB-CZ 4.34Å; D342-Y403 WeakPolarHBondContact O-CB 3.17Å; D342-N405 PolarHBondContact O-ND2 3.14Å; D342-N405 PolarHBondContact OD1-ND2 3.5Å; D342-F407 HydrophobicContact CB-CD1 4.32Å; D342-F407 HydrophobicContact CB-CD2 4.49Å; D342-F407 HydrophobicContact CB-CG 4.24Å
343Q94.3Very high92.1Very high19 Ų1921.8 Ų21.89%0.08914%0.135CC..  trans-134.831.8175.2-149.8-178.9-49.500112.2S247 S253 Y403S247-Q343 PolarHBondContact OG-N 2.95Å; S247-Q343 VanDerWaalsContact OG-N 3.07Å; S253-Q343 VanDerWaalsContact CA-NE2 3.26Å; S253-Q343 WeakPolarHBondContact CB-O 3.13Å; Q343-Y403 HydrophobicContact CG-CD1 4.04Å; Q343-Y403 HydrophobicContact CG-CG 4.38Å; Q343-Y403 VanDerWaalsContact OE1-CD1 3.3Å
344T93.4Very high92Very high24 Ų2419.3 Ų19.315%0.14711%0.109CC..SBendtrans-64.9162.9164.1560000110.4D342 L346 Y354 N405D342-T344 PolarHBondContact OD1-N 2.79Å; D342-T344 PolarHBondContact OD1-OG1 3.39Å; D342-T344 PolarHBondContact OD2-OG1 2.87Å; T344-L346 VanDerWaalsContact C-N 3.34Å; T344-L346 PolarHBondContact O-N 3.11Å; T344-L346 VanDerWaalsContact O-N 3.07Å; T344-L346 WeakPolarHBondContact OG1-CD2 3.43Å; T344-Y354 HydrophobicContact CG2-CD2 4.23Å; T344-Y354 HydrophobicContact CG2-CE2 4.45Å; T344-Y354 WeakPolarHBondContact OG1-CD2 3.26Å; T344-N405 PolarHBondContact N-ND2 2.82Å; T344-N405 WeakPolarHBondContact O-CB 3.35Å; T344-N405 PolarHBondContact O-ND2 3.13Å
345S89.1Confident91.9Very high41 Ų4118.3 Ų18.329%0.28710%0.103SC..  trans-90.364-170.5-69.70000112.3H347 N348 G353S345-H347 VanDerWaalsContact CB-CE1 3.46Å; S345-H347 WeakPolarHBondContact CB-CE1 3.31Å; S345-H347 PolarHBondContact O-N 2.71Å; S345-N348 CarbonylContact O-C 3.54Å; S345-N348 WeakPolarHBondContact O-CA 3.46Å; S345-N348 PolarHBondContact O-N 3.31Å; S345-G353 WeakPolarHBondContact CA-O 3.08Å; S345-G353 WeakPolarHBondContact CB-O 3.15Å; S345-G353 PolarHBondContact N-O 3.3Å; S345-G353 CarbonylContact O-C 3.58Å; S345-G353 VanDerWaalsContact O-CA 3.31Å; S345-G353 WeakPolarHBondContact O-CA 3.41Å
346L91.9Very high91.9Very high0 Ų016.3 Ų16.30%09%0.092CC..THydrogen-bonded Turntrans-72.3-9.2-177.4-88.5-71.4000113.7T344 N348 P349 Y354 L383 N405 A406 F407 E410T344-L346 VanDerWaalsContact C-N 3.34Å; T344-L346 PolarHBondContact O-N 3.11Å; T344-L346 VanDerWaalsContact O-N 3.07Å; T344-L346 WeakPolarHBondContact OG1-CD2 3.43Å; L346-N348 PolarHBondContact O-N 3.27Å; L346-P349 HydrophobicContact CD1-CB 3.76Å; L346-P349 VanDerWaalsContact O-CD 3.28Å; L346-P349 WeakPolarHBondContact O-CD 3.06Å; L346-Y354 HydrophobicContact CD1-CD2 4.45Å; L346-Y354 HydrophobicContact CD1-CG 4.47Å; L346-Y354 HydrophobicContact CD2-CD2 3.42Å; L346-Y354 VanDerWaalsContact CD2-CD2 3.42Å; L346-Y354 HydrophobicContact CD2-CE2 4.2Å; L346-Y354 HydrophobicContact CD2-CG 4.03Å; L346-Y354 HydrophobicContact CG-CD2 4.49Å; L346-L383 HydrophobicContact CD1-CD1 3.99Å; L346-L383 HydrophobicContact CD1-CD2 3.87Å; L346-N405 CarbonylContact C-O 3.59Å; L346-N405 WeakPolarHBondContact CA-O 3.25Å; L346-N405 WeakPolarHBondContact CB-O 3.46Å; L346-N405 PolarHBondContact N-O 2.97Å; L346-A406 HydrophobicContact CB-CB 4.46Å; L346-F407 HydrophobicContact CG-CB 4.41Å; L346-F407 HydrophobicContact CG-CD2 4.37Å; L346-E410 HydrophobicContact CB-CG 4.34Å; L346-E410 HydrophobicContact CD1-CB 3.62Å; L346-E410 HydrophobicContact CD1-CG 4.03Å; L346-E410 HydrophobicContact CG-CB 4.45Å; L346-E410 WeakPolarHBondContact O-CG 3.29Å
347H83.6Confident91.9Very high11 Ų1116.9 Ų16.95%0.05110%0.095CC..THydrogen-bonded Turntrans-60.5-24.5162.768.4-77.9000111.3G126 R188 S345 N405 V594G126-H347 PolarHBondContact O-NE2 2.68Å; R188-H347 PolarHBondContact NH1-O 3.33Å; R188-H347 PolarHBondContact NH2-O 3.15Å; S345-H347 VanDerWaalsContact CB-CE1 3.46Å; S345-H347 WeakPolarHBondContact CB-CE1 3.31Å; S345-H347 PolarHBondContact O-N 2.71Å; H347-N405 PolarHBondContact N-O 3.18Å; H347-V594 WeakPolarHBondContact CA-O 3.49Å; H347-V594 WeakPolarHBondContact CB-O 3.16Å
348N83.8Confident91.7Very high18 Ų1820.2 Ų20.210%0.09612%0.117CC..SBendtrans-131.751.7-177.4-65.9-10.8000114.5N128 R188 S345 L346 Y350 N351 G353N128-N348 PolarHBondContact ND2-ND2 3.16Å; N128-N348 PolarHBondContact OD1-ND2 2.92Å; N128-N348 VanDerWaalsContact OD1-ND2 3.1Å; R188-N348 VanDerWaalsContact NH2-CA 3.3Å; S345-N348 CarbonylContact O-C 3.54Å; S345-N348 WeakPolarHBondContact O-CA 3.46Å; S345-N348 PolarHBondContact O-N 3.31Å; L346-N348 PolarHBondContact O-N 3.27Å; N348-Y350 VanDerWaalsContact C-N 3.34Å; N348-Y350 PolarHBondContact O-N 3.49Å; N348-N351 PolarHBondContact O-N 3Å; N348-G353 VanDerWaalsContact O-CA 3.25Å; N348-G353 WeakPolarHBondContact O-CA 3.46Å; N348-G353 PolarHBondContact O-N 3.24Å
349P88.8Confident91.6Very high0 Ų021.5 Ų21.50%012%0.124CC..Iπ-helixtrans-66.9-31.7-161.328.8-30.2000113.9L346 Y354 V379 E410L346-P349 HydrophobicContact CD1-CB 3.76Å; L346-P349 VanDerWaalsContact O-CD 3.28Å; L346-P349 WeakPolarHBondContact O-CD 3.06Å; P349-Y354 PolarHBondContact O-N 2.95Å; P349-V379 HydrophobicContact CB-CG1 4.39Å; P349-E410 HydrophobicContact CG-CG 4.15Å
350Y88.6Confident91.3Very high46 Ų4624.1 Ų24.118%0.1814%0.143CC..Iπ-helixtrans-95.5-4.4-173.9-46.7-49.9000114.3N348 M368 F375 Q376 V379 Q380N348-Y350 VanDerWaalsContact C-N 3.34Å; N348-Y350 PolarHBondContact O-N 3.49Å; Y350-M368 WeakPolarHBondContact O-CG 3.2Å; Y350-F375 WeakPolarHBondContact O-CE1 3.39Å; Y350-Q376 HydrophobicContact CD1-CB 3.9Å; Y350-Q376 HydrophobicContact CD1-CG 3.9Å; Y350-Q376 HydrophobicContact CE1-CB 4.08Å; Y350-Q376 HydrophobicContact CE1-CG 3.59Å; Y350-Q376 HydrophobicContact CE2-CG 4.25Å; Y350-Q376 HydrophobicContact CG-CB 4.32Å; Y350-Q376 HydrophobicContact CG-CG 4.36Å; Y350-V379 HydrophobicContact CD1-CB 4.26Å; Y350-V379 HydrophobicContact CD1-CG1 4.06Å; Y350-V379 HydrophobicContact CE1-CB 4.19Å; Y350-V379 HydrophobicContact CE1-CG1 3.77Å; Y350-Q380 PolarHBondContact OH-NE2 3.47Å
351N80.4Confident90.8Very high81 Ų8127 Ų2743%0.43316%0.155SC..Iπ-helixtrans-119.642.9-176.4-64.7-22.3000111.2N348 M368N348-N351 PolarHBondContact O-N 3Å; N351-M368 VanDerWaalsContact C-SD 3.59Å
352G79.7Confident90.4Very high23 Ų2337 Ų3724%0.23719%0.193CC..Iπ-helixtrans83.314.1179.200000114.9Y355 M368G352-Y355 WeakPolarHBondContact O-CE2 3.15Å; G352-M368 VanDerWaalsContact N-CE 3.32Å; G352-M368 PolarHBondContact N-SD 2.93Å
353G85.1Confident90.2Very high10 Ų1042 Ų4210%0.10322%0.216CC..Iπ-helixtrans-84.1-28.5174.700000114.4S345 N348S345-G353 WeakPolarHBondContact CA-O 3.08Å; S345-G353 WeakPolarHBondContact CB-O 3.15Å; S345-G353 PolarHBondContact N-O 3.3Å; S345-G353 CarbonylContact O-C 3.58Å; S345-G353 VanDerWaalsContact O-CA 3.31Å; S345-G353 WeakPolarHBondContact O-CA 3.41Å; N348-G353 VanDerWaalsContact O-CA 3.25Å; N348-G353 WeakPolarHBondContact O-CA 3.46Å; N348-G353 PolarHBondContact O-N 3.24Å
354Y93.8Very high90.1Very high3 Ų341.1 Ų41.11%0.01221%0.212CC..  trans-134.5136.9176.7-169.7-98.3000110.8V319 T344 L346 P349 V379 S382 L383 H386V319-Y354 WeakPolarHBondContact CG2-OH 3.17Å; T344-Y354 HydrophobicContact CG2-CD2 4.23Å; T344-Y354 HydrophobicContact CG2-CE2 4.45Å; T344-Y354 WeakPolarHBondContact OG1-CD2 3.26Å; L346-Y354 HydrophobicContact CD1-CD2 4.45Å; L346-Y354 HydrophobicContact CD1-CG 4.47Å; L346-Y354 HydrophobicContact CD2-CD2 3.42Å; L346-Y354 VanDerWaalsContact CD2-CD2 3.42Å; L346-Y354 HydrophobicContact CD2-CE2 4.2Å; L346-Y354 HydrophobicContact CD2-CG 4.03Å; L346-Y354 HydrophobicContact CG-CD2 4.49Å; P349-Y354 PolarHBondContact O-N 2.95Å; Y354-V379 HydrophobicContact CD1-CG1 3.84Å; Y354-V379 HydrophobicContact CD1-CG2 4.38Å; Y354-S382 PolarHBondContact OH-OG 3.47Å; Y354-L383 HydrophobicContact CD2-CD2 4.42Å; Y354-L383 HydrophobicContact CE1-CD2 4.08Å; Y354-L383 HydrophobicContact CE1-CG 4.17Å; Y354-L383 HydrophobicContact CE2-CD2 3.94Å; Y354-H386 PolarHBondContact OH-ND1 3.49Å; Y354-H386 VanDerWaalsContact OH-ND1 3.17Å
355Y95.3Very high89.6Confident41 Ų4142.7 Ų42.716%0.16122%0.22CC..  trans-113.2119.1-178.8-74.1-90.8000109.7V272 N317 G352 F361 A364 N365 M368V272-Y355 HydrophobicContact CG2-CD2 3.76Å; V272-Y355 HydrophobicContact CG2-CG 3.75Å; N317-Y355 PolarHBondContact ND2-O 3.24Å; G352-Y355 WeakPolarHBondContact O-CE2 3.15Å; Y355-F361 AromaticContact CD1-CD2 3.68Å; Y355-F361 HydrophobicContact CD1-CD2 3.68Å; Y355-F361 HydrophobicContact CD1-CE2 4.19Å; Y355-F361 HydrophobicContact CD2-CD2 4.45Å; Y355-F361 HydrophobicContact CD2-CE2 4.48Å; Y355-F361 AromaticContact CE1-CD2 3.35Å; Y355-F361 HydrophobicContact CE1-CD2 3.35Å; Y355-F361 AromaticContact CE1-CE2 3.46Å; Y355-F361 HydrophobicContact CE1-CE2 3.46Å; Y355-F361 VanDerWaalsContact CE1-CE2 3.46Å; Y355-F361 HydrophobicContact CE1-CG 4.36Å; Y355-F361 HydrophobicContact CE2-CD2 4.18Å; Y355-F361 AromaticContact CE2-CE2 3.8Å; Y355-F361 HydrophobicContact CE2-CE2 3.8Å; Y355-F361 HydrophobicContact CG-CD2 4.24Å; Y355-F361 AromaticContact CZ-CD2 3.64Å; Y355-F361 AromaticContact CZ-CE2 3.24Å; Y355-F361 VanDerWaalsContact OH-CE2 3.3Å; Y355-F361 WeakPolarHBondContact OH-CE2 3.5Å; Y355-A364 HydrophobicContact CD1-CB 3.54Å; Y355-A364 HydrophobicContact CE1-CB 3.96Å; Y355-N365 WeakPolarHBondContact CE1-OD1 3.15Å; Y355-N365 PolarHBondContact OH-OD1 3.47Å; Y355-M368 HydrophobicContact CE1-CE 4.45Å
356P96.8Very high89.6Confident0 Ų046.7 Ų46.70%023%0.234CC..  trans-76.3141.9-173.531.1-35.5000112.3L359 F375 V378 V379P356-L359 HydrophobicContact CG-CB 4.34Å; P356-L359 HydrophobicContact CG-CD1 3.85Å; P356-L359 HydrophobicContact CG-CG 4.19Å; P356-L359 PolarHBondContact O-N 2.63Å; P356-F375 HydrophobicContact CG-CE2 4.13Å; P356-V378 HydrophobicContact CB-CB 4.38Å; P356-V378 HydrophobicContact CB-CG1 3.73Å; P356-V378 HydrophobicContact CG-CB 4.33Å; P356-V378 HydrophobicContact CG-CG1 3.86Å; P356-V379 HydrophobicContact CB-CG2 4.39Å; P356-V379 HydrophobicContact CG-CG2 4.24Å
357V97.1Very high89.5Confident15 Ų1548.4 Ų48.49%0.09124%0.243CC..THydrogen-bonded Turntrans-54.9-34.2-176.865.70000116.5N317 V319 D320 L359 S382 R385N317-V357 HydrophobicContact CB-CB 4.41Å; N317-V357 HydrophobicContact CB-CG2 4.16Å; N317-V357 WeakPolarHBondContact ND2-CA 3.43Å; N317-V357 PolarHBondContact ND2-N 3.4Å; V319-V357 HydrophobicContact CB-CB 3.9Å; V319-V357 HydrophobicContact CB-CG1 4.29Å; V319-V357 HydrophobicContact CB-CG2 4.04Å; V319-V357 HydrophobicContact CG1-CB 4.18Å; V319-V357 HydrophobicContact CG1-CG1 4.04Å; V319-V357 HydrophobicContact CG1-CG2 4.25Å; V319-V357 HydrophobicContact CG2-CB 4.38Å; D320-V357 WeakPolarHBondContact OD1-CG2 3.49Å; V357-L359 PolarHBondContact O-N 3.28Å; V357-S382 PolarHBondContact N-OG 3.49Å; V357-S382 VanDerWaalsContact N-OG 3.12Å; V357-R385 VanDerWaalsContact CG1-CZ 3.44Å
358P95.1Very high89.7Confident72 Ų7249.3 Ų49.347%0.46825%0.248SC..THydrogen-bonded Turntrans-74-8.9-178.3-15.833.4000114.1V378P358-V378 HydrophobicContact CB-CG1 4.46Å; P358-V378 HydrophobicContact CG-CG1 3.99Å
359L94.8Very high89.5Confident45 Ų4552.5 Ų52.524%0.23627%0.271CS..SBendtrans-116.5140.2-174.6-58-179.4000110.6P356 V357 Q363 A364 L367 V378P356-L359 HydrophobicContact CG-CB 4.34Å; P356-L359 HydrophobicContact CG-CD1 3.85Å; P356-L359 HydrophobicContact CG-CG 4.19Å; P356-L359 PolarHBondContact O-N 2.63Å; V357-L359 PolarHBondContact O-N 3.28Å; L359-Q363 HydrophobicContact CB-CB 4.3Å; L359-Q363 HydrophobicContact CD2-CB 4.48Å; L359-A364 HydrophobicContact CB-CB 4.24Å; L359-A364 HydrophobicContact CD1-CB 4.44Å; L359-L367 HydrophobicContact CD1-CD2 3.66Å; L359-V378 HydrophobicContact CD1-CG1 4.3Å; L359-V378 HydrophobicContact CG-CG1 4.34Å
360S93.3Very high89.4Confident58 Ų5857 Ų5741%0.40630%0.299SS..  trans-65.9157.5163.165.40000110.8R362 Q363 A364S360-R362 PolarHBondContact O-N 3.18Å; S360-Q363 PolarHBondContact O-N 3.26Å; S360-Q363 WeakPolarHBondContact OG-CB 3.44Å; S360-Q363 VanDerWaalsContact OG-CD 3.24Å; S360-Q363 VanDerWaalsContact OG-CG 3.28Å; S360-Q363 WeakPolarHBondContact OG-CG 3.34Å; S360-Q363 PolarHBondContact OG-N 3.26Å; S360-Q363 PolarHBondContact OG-OE1 3.05Å; S360-A364 WeakPolarHBondContact O-CB 3.08Å; S360-A364 PolarHBondContact O-N 2.74Å
361F87.4Confident89.4Confident61 Ų6158.5 Ų58.527%0.26831%0.31SS..Hα-helixtrans-50.9-42.8176.5-179.5-107.1000112.8V272 D273 Y355 A364 N365V272-F361 HydrophobicContact CG2-CD2 4.1Å; D273-F361 HydrophobicContact CB-CD2 4.11Å; D273-F361 HydrophobicContact CB-CE1 4.36Å; D273-F361 HydrophobicContact CB-CE2 3.64Å; D273-F361 HydrophobicContact CB-CZ 3.78Å; D273-F361 VanDerWaalsContact CG-CZ 3.42Å; D273-F361 WeakPolarHBondContact OD2-CZ 3.44Å; Y355-F361 AromaticContact CD1-CD2 3.68Å; Y355-F361 HydrophobicContact CD1-CD2 3.68Å; Y355-F361 HydrophobicContact CD1-CE2 4.19Å; Y355-F361 HydrophobicContact CD2-CD2 4.45Å; Y355-F361 HydrophobicContact CD2-CE2 4.48Å; Y355-F361 AromaticContact CE1-CD2 3.35Å; Y355-F361 HydrophobicContact CE1-CD2 3.35Å; Y355-F361 AromaticContact CE1-CE2 3.46Å; Y355-F361 HydrophobicContact CE1-CE2 3.46Å; Y355-F361 VanDerWaalsContact CE1-CE2 3.46Å; Y355-F361 HydrophobicContact CE1-CG 4.36Å; Y355-F361 HydrophobicContact CE2-CD2 4.18Å; Y355-F361 AromaticContact CE2-CE2 3.8Å; Y355-F361 HydrophobicContact CE2-CE2 3.8Å; Y355-F361 HydrophobicContact CG-CD2 4.24Å; Y355-F361 AromaticContact CZ-CD2 3.64Å; Y355-F361 AromaticContact CZ-CE2 3.24Å; Y355-F361 VanDerWaalsContact OH-CE2 3.3Å; Y355-F361 WeakPolarHBondContact OH-CE2 3.5Å; F361-A364 PolarHBondContact O-N 2.74Å; F361-N365 WeakPolarHBondContact CD1-ND2 3.37Å; F361-N365 WeakPolarHBondContact CE1-ND2 3.36Å; F361-N365 VanDerWaalsContact CZ-ND2 3.28Å; F361-N365 WeakPolarHBondContact CZ-ND2 3.3Å; F361-N365 PolarHBondContact O-N 3.37Å; F361-N365 PolarHBondContact O-ND2 2.82Å; F361-N365 VanDerWaalsContact O-ND2 3.16Å
362R89.6Confident89.8Confident209 Ų20957.9 Ų57.979%0.78931%0.311SS*.Hα-helixtrans-65.2-44.9177.9-170.2-179.5-170.2176.74112.5S360 N365 Q366S360-R362 PolarHBondContact O-N 3.18Å; R362-N365 PolarHBondContact O-N 3.27Å; R362-Q366 PolarHBondContact O-N 2.97Å; R362-Q366 VanDerWaalsContact O-N 3.11Å
363Q92.4Very high90.3Very high104 Ų10458.8 Ų58.849%0.48632%0.319SS..Hα-helixtrans-65.3-41.3178.4-73.5164.5-4400111.3L359 S360 Q366 L367L359-Q363 HydrophobicContact CB-CB 4.3Å; L359-Q363 HydrophobicContact CD2-CB 4.48Å; S360-Q363 PolarHBondContact O-N 3.26Å; S360-Q363 WeakPolarHBondContact OG-CB 3.44Å; S360-Q363 VanDerWaalsContact OG-CD 3.24Å; S360-Q363 VanDerWaalsContact OG-CG 3.28Å; S360-Q363 WeakPolarHBondContact OG-CG 3.34Å; S360-Q363 PolarHBondContact OG-N 3.26Å; S360-Q363 PolarHBondContact OG-OE1 3.05Å; Q363-Q366 PolarHBondContact O-N 3.47Å; Q363-L367 WeakPolarHBondContact O-CB 3.33Å; Q363-L367 PolarHBondContact O-N 3.01Å
364A91.2Very high90.7Very high1 Ų160.6 Ų60.61%0.00833%0.33CS..Hα-helixtrans-60.1-47.5176.100000111.9Y355 L359 S360 F361 Q366 L367 M368 F375Y355-A364 HydrophobicContact CD1-CB 3.54Å; Y355-A364 HydrophobicContact CE1-CB 3.96Å; L359-A364 HydrophobicContact CB-CB 4.24Å; L359-A364 HydrophobicContact CD1-CB 4.44Å; S360-A364 WeakPolarHBondContact O-CB 3.08Å; S360-A364 PolarHBondContact O-N 2.74Å; F361-A364 PolarHBondContact O-N 2.74Å; A364-Q366 VanDerWaalsContact C-N 3.31Å; A364-Q366 PolarHBondContact O-N 3.36Å; A364-L367 PolarHBondContact O-N 3.16Å; A364-M368 VanDerWaalsContact O-CB 3.25Å; A364-M368 WeakPolarHBondContact O-CB 3.45Å; A364-M368 PolarHBondContact O-N 3.39Å; A364-F375 HydrophobicContact CB-CE2 3.93Å
365N84.9Confident90.8Very high57 Ų5760.5 Ų60.531%0.30533%0.33SS..Hα-helixtrans-62-37.4177.1-73.6-34.1000112.7Y355 F361 R362Y355-N365 WeakPolarHBondContact CE1-OD1 3.15Å; Y355-N365 PolarHBondContact OH-OD1 3.47Å; F361-N365 WeakPolarHBondContact CD1-ND2 3.37Å; F361-N365 WeakPolarHBondContact CE1-ND2 3.36Å; F361-N365 VanDerWaalsContact CZ-ND2 3.28Å; F361-N365 WeakPolarHBondContact CZ-ND2 3.3Å; F361-N365 PolarHBondContact O-N 3.37Å; F361-N365 PolarHBondContact O-ND2 2.82Å; F361-N365 VanDerWaalsContact O-ND2 3.16Å; R362-N365 PolarHBondContact O-N 3.27Å
366Q88Confident90.7Very high126 Ų12662.1 Ų62.159%0.58934%0.339SS*.Hα-helixtrans-66.7-53174.8-174.7176.3-100111R362 Q363 A364 M368 S369 T370R362-Q366 PolarHBondContact O-N 2.97Å; R362-Q366 VanDerWaalsContact O-N 3.11Å; Q363-Q366 PolarHBondContact O-N 3.47Å; A364-Q366 VanDerWaalsContact C-N 3.31Å; A364-Q366 PolarHBondContact O-N 3.36Å; Q366-M368 VanDerWaalsContact C-N 3.3Å; Q366-M368 PolarHBondContact O-N 3.36Å; Q366-S369 PolarHBondContact O-N 3.42Å; Q366-S369 PolarHBondContact O-OG 3.37Å; Q366-T370 HydrophobicContact CG-CG2 4.25Å; Q366-T370 PolarHBondContact O-N 3Å; Q366-T370 PolarHBondContact O-OG1 3.1Å
367L89.9Confident90.7Very high36 Ų3665.4 Ų65.419%0.18836%0.362CS..Hα-helixtrans-60.3-39.8-176.4-172.266.6000112.2L359 Q363 A364 S369 T370 D371 C374 F375L359-L367 HydrophobicContact CD1-CD2 3.66Å; Q363-L367 WeakPolarHBondContact O-CB 3.33Å; Q363-L367 PolarHBondContact O-N 3.01Å; A364-L367 PolarHBondContact O-N 3.16Å; L367-S369 PolarHBondContact O-N 3.35Å; L367-S369 VanDerWaalsContact O-N 3.16Å; L367-T370 PolarHBondContact O-N 3.46Å; L367-D371 HydrophobicContact CD1-CB 3.99Å; L367-D371 CarbonylContact O-C 3.58Å; L367-D371 PolarHBondContact O-N 2.95Å; L367-C374 HydrophobicContact CD1-CB 4.27Å; L367-F375 HydrophobicContact CB-CD2 4.44Å; L367-F375 HydrophobicContact CD2-CB 4.28Å; L367-F375 HydrophobicContact CD2-CD2 4.35Å; L367-F375 HydrophobicContact CG-CB 4.14Å
368M86.8Confident90.7Very high30 Ų3066.1 Ų66.115%0.14837%0.366CS..Hα-helixtrans-54.8-33.2176.3-173.3-167-48.900112.8Y350 N351 G352 Y355 A364 Q366 P372 F375Y350-M368 WeakPolarHBondContact O-CG 3.2Å; N351-M368 VanDerWaalsContact C-SD 3.59Å; G352-M368 VanDerWaalsContact N-CE 3.32Å; G352-M368 PolarHBondContact N-SD 2.93Å; Y355-M368 HydrophobicContact CE1-CE 4.45Å; A364-M368 VanDerWaalsContact O-CB 3.25Å; A364-M368 WeakPolarHBondContact O-CB 3.45Å; A364-M368 PolarHBondContact O-N 3.39Å; Q366-M368 VanDerWaalsContact C-N 3.3Å; Q366-M368 PolarHBondContact O-N 3.36Å; M368-P372 WeakPolarHBondContact O-CG 3.29Å; M368-F375 HydrophobicContact CB-CD1 4.07Å; M368-F375 HydrophobicContact CB-CD2 4.21Å; M368-F375 HydrophobicContact CB-CE1 4.24Å; M368-F375 HydrophobicContact CB-CE2 4.39Å; M368-F375 HydrophobicContact CB-CG 4.06Å; M368-F375 HydrophobicContact CB-CZ 4.41Å; M368-F375 HydrophobicContact CE-CE1 3.99Å; M368-F375 HydrophobicContact CE-CE2 4.37Å; M368-F375 HydrophobicContact CE-CZ 3.75Å; M368-F375 HydrophobicContact CG-CD1 3.97Å; M368-F375 HydrophobicContact CG-CE1 3.98Å; M368-F375 HydrophobicContact CG-CG 4.46Å; M368-F375 HydrophobicContact CG-CZ 4.5Å
369S81.3Confident90.8Very high84 Ų8462.7 Ų62.759%0.58734%0.344SS*.Hα-helixtrans-89.4-36.6177.969.30000113.6Q366 L367Q366-S369 PolarHBondContact O-N 3.42Å; Q366-S369 PolarHBondContact O-OG 3.37Å; L367-S369 PolarHBondContact O-N 3.35Å; L367-S369 VanDerWaalsContact O-N 3.16Å
370T85.9Confident91Very high95 Ų9562.6 Ų62.658%0.58334%0.342SS*.Hα-helixtrans-88-33.6-172.257.40000113.3Q366 L367Q366-T370 HydrophobicContact CG-CG2 4.25Å; Q366-T370 PolarHBondContact O-N 3Å; Q366-T370 PolarHBondContact O-OG1 3.1Å; L367-T370 PolarHBondContact O-N 3.46Å
371D89.1Confident91.2Very high78 Ų7863.8 Ų63.842%0.41734%0.341SS..  trans-147.980.1177.9-171-16000110.6L367 G373 C374 F375L367-D371 HydrophobicContact CD1-CB 3.99Å; L367-D371 CarbonylContact O-C 3.58Å; L367-D371 PolarHBondContact O-N 2.95Å; D371-G373 PolarHBondContact O-N 2.8Å; D371-G373 PolarHBondContact OD1-N 3.43Å; D371-C374 HydrophobicContact CB-CB 4.01Å; D371-C374 PolarHBondContact O-N 3.37Å; D371-C374 WeakPolarHBondContact OD1-CB 3.14Å; D371-C374 PolarHBondContact OD1-N 2.78Å; D371-C374 VanDerWaalsContact OD2-CB 3.31Å; D371-C374 WeakPolarHBondContact OD2-CB 3.42Å; D371-F375 PolarHBondContact O-N 3.27Å
372P87.4Confident91.7Very high68 Ų6860.9 Ų60.944%0.44233%0.328SS..Hα-helixtrans-59-31.1-179.6-22.531.3000113.6M368 F375 Q376M368-P372 WeakPolarHBondContact O-CG 3.29Å; P372-F375 PolarHBondContact O-N 2.9Å; P372-Q376 WeakPolarHBondContact O-CB 3.07Å; P372-Q376 PolarHBondContact O-N 3.11Å
373G91.6Very high92.2Very high41 Ų4150.9 Ų50.942%0.42329%0.291SS..Hα-helixtrans-70.3-42.5179.900000112.3D371 S377D371-G373 PolarHBondContact O-N 2.8Å; D371-G373 PolarHBondContact OD1-N 3.43Å; G373-S377 PolarHBondContact O-N 3.05Å; G373-S377 PolarHBondContact O-OG 3.08Å; G373-S377 VanDerWaalsContact O-OG 3.11Å
374C94Very high92.5Very high49 Ų4950.3 Ų50.333%0.33128%0.284SS..Hα-helixtrans-63-46.9170.5-174.50000110.8L367 D371 Q376 S377 V378L367-C374 HydrophobicContact CD1-CB 4.27Å; D371-C374 HydrophobicContact CB-CB 4.01Å; D371-C374 PolarHBondContact O-N 3.37Å; D371-C374 WeakPolarHBondContact OD1-CB 3.14Å; D371-C374 PolarHBondContact OD1-N 2.78Å; D371-C374 VanDerWaalsContact OD2-CB 3.31Å; D371-C374 WeakPolarHBondContact OD2-CB 3.42Å; C374-Q376 VanDerWaalsContact C-N 3.33Å; C374-Q376 PolarHBondContact O-N 3.02Å; C374-S377 WeakPolarHBondContact O-CB 3.22Å; C374-S377 PolarHBondContact O-N 3.49Å; C374-V378 WeakPolarHBondContact O-CG2 3.17Å; C374-V378 PolarHBondContact O-N 2.96Å
375F94.1Very high92.8Very high0 Ų053.8 Ų53.80%030%0.297CS..Hα-helixtrans-54.7-47.1178.3-176.3-108.1000112.4Y350 P356 A364 L367 M368 D371 P372 S377 V378 V379Y350-F375 WeakPolarHBondContact O-CE1 3.39Å; P356-F375 HydrophobicContact CG-CE2 4.13Å; A364-F375 HydrophobicContact CB-CE2 3.93Å; L367-F375 HydrophobicContact CB-CD2 4.44Å; L367-F375 HydrophobicContact CD2-CB 4.28Å; L367-F375 HydrophobicContact CD2-CD2 4.35Å; L367-F375 HydrophobicContact CG-CB 4.14Å; M368-F375 HydrophobicContact CB-CD1 4.07Å; M368-F375 HydrophobicContact CB-CD2 4.21Å; M368-F375 HydrophobicContact CB-CE1 4.24Å; M368-F375 HydrophobicContact CB-CE2 4.39Å; M368-F375 HydrophobicContact CB-CG 4.06Å; M368-F375 HydrophobicContact CB-CZ 4.41Å; M368-F375 HydrophobicContact CE-CE1 3.99Å; M368-F375 HydrophobicContact CE-CE2 4.37Å; M368-F375 HydrophobicContact CE-CZ 3.75Å; M368-F375 HydrophobicContact CG-CD1 3.97Å; M368-F375 HydrophobicContact CG-CE1 3.98Å; M368-F375 HydrophobicContact CG-CG 4.46Å; M368-F375 HydrophobicContact CG-CZ 4.5Å; D371-F375 PolarHBondContact O-N 3.27Å; P372-F375 PolarHBondContact O-N 2.9Å; F375-S377 VanDerWaalsContact C-N 3.31Å; F375-S377 PolarHBondContact O-N 2.98Å; F375-V378 PolarHBondContact O-N 3.16Å; F375-V379 HydrophobicContact CD1-CG2 4.16Å; F375-V379 HydrophobicContact CE1-CG2 3.75Å; F375-V379 HydrophobicContact CE2-CG2 4.22Å; F375-V379 HydrophobicContact CZ-CG2 3.77Å; F375-V379 WeakPolarHBondContact O-CG2 3.47Å; F375-V379 PolarHBondContact O-N 3Å
376Q94.8Very high93.4Very high76 Ų7651.1 Ų51.136%0.35528%0.283SS..Hα-helixtrans-56.4-44.4176170.9169.58.700112.2Y350 P372 C374 V378 V379 Q380Y350-Q376 HydrophobicContact CD1-CB 3.9Å; Y350-Q376 HydrophobicContact CD1-CG 3.9Å; Y350-Q376 HydrophobicContact CE1-CB 4.08Å; Y350-Q376 HydrophobicContact CE1-CG 3.59Å; Y350-Q376 HydrophobicContact CE2-CG 4.25Å; Y350-Q376 HydrophobicContact CG-CB 4.32Å; Y350-Q376 HydrophobicContact CG-CG 4.36Å; P372-Q376 WeakPolarHBondContact O-CB 3.07Å; P372-Q376 PolarHBondContact O-N 3.11Å; C374-Q376 VanDerWaalsContact C-N 3.33Å; C374-Q376 PolarHBondContact O-N 3.02Å; Q376-V378 PolarHBondContact O-N 3.45Å; Q376-V379 PolarHBondContact O-N 3.23Å; Q376-Q380 WeakPolarHBondContact O-CG 3.06Å; Q376-Q380 PolarHBondContact O-N 2.85Å
377S96.4Very high93.9Very high68 Ų6845.1 Ų45.148%0.47626%0.255SS..Hα-helixtrans-64.6-40.2-179.2-62.30000112G373 C374 F375 Q380 E381G373-S377 PolarHBondContact O-N 3.05Å; G373-S377 PolarHBondContact O-OG 3.08Å; G373-S377 VanDerWaalsContact O-OG 3.11Å; C374-S377 WeakPolarHBondContact O-CB 3.22Å; C374-S377 PolarHBondContact O-N 3.49Å; F375-S377 VanDerWaalsContact C-N 3.31Å; F375-S377 PolarHBondContact O-N 2.98Å; S377-Q380 PolarHBondContact O-N 2.52Å; S377-E381 PolarHBondContact O-N 3.33Å; S377-E381 VanDerWaalsContact O-N 3.12Å
378V97.2Very high94.3Very high31 Ų3150.2 Ų50.219%0.18828%0.275CS..Hα-helixtrans-70.9-36.1177.1-170.80000111.5P356 P358 L359 C374 F375 Q376 E381 S382P356-V378 HydrophobicContact CB-CB 4.38Å; P356-V378 HydrophobicContact CB-CG1 3.73Å; P356-V378 HydrophobicContact CG-CB 4.33Å; P356-V378 HydrophobicContact CG-CG1 3.86Å; P358-V378 HydrophobicContact CB-CG1 4.46Å; P358-V378 HydrophobicContact CG-CG1 3.99Å; L359-V378 HydrophobicContact CD1-CG1 4.3Å; L359-V378 HydrophobicContact CG-CG1 4.34Å; C374-V378 WeakPolarHBondContact O-CG2 3.17Å; C374-V378 PolarHBondContact O-N 2.96Å; F375-V378 PolarHBondContact O-N 3.16Å; Q376-V378 PolarHBondContact O-N 3.45Å; V378-E381 PolarHBondContact O-N 3.34Å; V378-S382 WeakPolarHBondContact O-CB 3.37Å; V378-S382 PolarHBondContact O-N 2.82Å
379V97.6Very high94.9Very high0 Ų048.9 Ų48.90%027%0.269CS..Hα-helixtrans-58.5-49.1171.21650000111P349 Y350 Y354 P356 F375 Q376 E381 S382 L383P349-V379 HydrophobicContact CB-CG1 4.39Å; Y350-V379 HydrophobicContact CD1-CB 4.26Å; Y350-V379 HydrophobicContact CD1-CG1 4.06Å; Y350-V379 HydrophobicContact CE1-CB 4.19Å; Y350-V379 HydrophobicContact CE1-CG1 3.77Å; Y354-V379 HydrophobicContact CD1-CG1 3.84Å; Y354-V379 HydrophobicContact CD1-CG2 4.38Å; P356-V379 HydrophobicContact CB-CG2 4.39Å; P356-V379 HydrophobicContact CG-CG2 4.24Å; F375-V379 HydrophobicContact CD1-CG2 4.16Å; F375-V379 HydrophobicContact CE1-CG2 3.75Å; F375-V379 HydrophobicContact CE2-CG2 4.22Å; F375-V379 HydrophobicContact CZ-CG2 3.77Å; F375-V379 WeakPolarHBondContact O-CG2 3.47Å; F375-V379 PolarHBondContact O-N 3Å; Q376-V379 PolarHBondContact O-N 3.23Å; V379-E381 PolarHBondContact O-N 2.83Å; V379-S382 PolarHBondContact O-N 2.89Å; V379-L383 HydrophobicContact CG1-CD1 4.2Å; V379-L383 WeakPolarHBondContact O-CG 3.46Å; V379-L383 PolarHBondContact O-N 2.85Å
380Q97.9Very high95.7Very high42 Ų4244.9 Ų44.920%0.19624%0.242CC..Hα-helixtrans-61.8-41.4180-71.7177.2-9.300112.4Y350 Q376 S377 L383 R384 A414Y350-Q380 PolarHBondContact OH-NE2 3.47Å; Q376-Q380 WeakPolarHBondContact O-CG 3.06Å; Q376-Q380 PolarHBondContact O-N 2.85Å; S377-Q380 PolarHBondContact O-N 2.52Å; Q380-L383 PolarHBondContact O-N 2.73Å; Q380-R384 PolarHBondContact O-N 2.82Å; Q380-R384 VanDerWaalsContact O-N 3.13Å; Q380-A414 HydrophobicContact CB-CB 3.77Å; Q380-A414 HydrophobicContact CG-CB 3.84Å
381E97.9Very high96.3Very high83 Ų8340.7 Ų40.739%0.38822%0.216SC..Hα-helixtrans-63.9-41.2175-178.454.4-151.600112.3S377 V378 V379 L383 R384 R385S377-E381 PolarHBondContact O-N 3.33Å; S377-E381 VanDerWaalsContact O-N 3.12Å; V378-E381 PolarHBondContact O-N 3.34Å; V379-E381 PolarHBondContact O-N 2.83Å; E381-L383 VanDerWaalsContact C-N 3.32Å; E381-L383 PolarHBondContact O-N 3.24Å; E381-R384 PolarHBondContact O-N 2.87Å; E381-R384 IonicContact OE2-CZ 3.39Å; E381-R384 IonicContact OE2-NE 3.48Å; E381-R384 PolarHBondContact OE2-NE 3.01Å; E381-R384 IonicContact OE2-NH2 3.55Å; E381-R384 PolarHBondContact OE2-NH2 2.67Å; E381-R385 PolarHBondContact O-N 3.24Å; E381-R385 VanDerWaalsContact O-N 3.13Å
382S98.4Very high96.7Very high0 Ų042.3 Ų42.30%022%0.219CC..Hα-helixtrans-63.9-36176-178.10000112.5Y354 V357 V378 V379 R385 H386Y354-S382 PolarHBondContact OH-OG 3.47Å; V357-S382 PolarHBondContact N-OG 3.49Å; V357-S382 VanDerWaalsContact N-OG 3.12Å; V378-S382 WeakPolarHBondContact O-CB 3.37Å; V378-S382 PolarHBondContact O-N 2.82Å; V379-S382 PolarHBondContact O-N 2.89Å; S382-R385 PolarHBondContact O-N 2.83Å; S382-H386 WeakPolarHBondContact O-CB 3.37Å; S382-H386 PolarHBondContact O-N 2.99Å
383L98.6Very high97.3Very high0 Ų039.1 Ų39.10%020%0.198CC..Hα-helixtrans-65.4-39.6174.5-72.2170.3000112.2L346 Y354 V379 Q380 E381 H386 I387 F407 E410 A414L346-L383 HydrophobicContact CD1-CD1 3.99Å; L346-L383 HydrophobicContact CD1-CD2 3.87Å; Y354-L383 HydrophobicContact CD2-CD2 4.42Å; Y354-L383 HydrophobicContact CE1-CD2 4.08Å; Y354-L383 HydrophobicContact CE1-CG 4.17Å; Y354-L383 HydrophobicContact CE2-CD2 3.94Å; V379-L383 HydrophobicContact CG1-CD1 4.2Å; V379-L383 WeakPolarHBondContact O-CG 3.46Å; V379-L383 PolarHBondContact O-N 2.85Å; Q380-L383 PolarHBondContact O-N 2.73Å; E381-L383 VanDerWaalsContact C-N 3.32Å; E381-L383 PolarHBondContact O-N 3.24Å; L383-H386 WeakPolarHBondContact O-CB 3.46Å; L383-H386 PolarHBondContact O-N 2.94Å; L383-I387 PolarHBondContact O-N 2.74Å; L383-F407 HydrophobicContact CD2-CD2 4.04Å; L383-F407 HydrophobicContact CD2-CE2 3.84Å; L383-E410 HydrophobicContact CD1-CB 4.29Å; L383-A414 HydrophobicContact CB-CB 4.25Å; L383-A414 HydrophobicContact CD1-CB 4.22Å
384R98.5Very high97.6Very high92 Ų9238.5 Ų38.535%0.34719%0.187SC..Hα-helixtrans-60.4-45.3174.5-71.9-173.7-73.5-103.74.4111.7Q380 E381 K388 A414 A416Q380-R384 PolarHBondContact O-N 2.82Å; Q380-R384 VanDerWaalsContact O-N 3.13Å; E381-R384 PolarHBondContact O-N 2.87Å; E381-R384 IonicContact OE2-CZ 3.39Å; E381-R384 IonicContact OE2-NE 3.48Å; E381-R384 PolarHBondContact OE2-NE 3.01Å; E381-R384 IonicContact OE2-NH2 3.55Å; E381-R384 PolarHBondContact OE2-NH2 2.67Å; R384-K388 WeakPolarHBondContact O-CB 3.2Å; R384-K388 PolarHBondContact O-N 3.16Å; R384-A414 WeakPolarHBondContact CD-O 3.44Å; R384-A414 PolarHBondContact NH1-O 3.04Å; R384-A416 HydrophobicContact CG-CB 4.23Å
385R98.4Very high97.7Very high74 Ų7441.4 Ų41.428%0.27920%0.199SC..Hα-helixtrans-62.7-43.8175.1-74.4176.858-171.7-5.8112.6V319 E323 V357 E381 S382 I387 K388 A389V319-R385 HydrophobicContact CG1-CB 4.03Å; E323-R385 VanDerWaalsContact CD-NH2 3.28Å; E323-R385 IonicContact OE1-CZ 2.83Å; E323-R385 IonicContact OE1-NE 3.21Å; E323-R385 PolarHBondContact OE1-NE 3.24Å; E323-R385 IonicContact OE1-NH2 3.9Å; E323-R385 PolarHBondContact OE1-NH2 3.02Å; E323-R385 IonicContact OE2-CZ 2.75Å; E323-R385 IonicContact OE2-NH2 3.65Å; E323-R385 PolarHBondContact OE2-NH2 3.35Å; V357-R385 VanDerWaalsContact CG1-CZ 3.44Å; E381-R385 PolarHBondContact O-N 3.24Å; E381-R385 VanDerWaalsContact O-N 3.13Å; S382-R385 PolarHBondContact O-N 2.83Å; R385-I387 PolarHBondContact O-N 3.45Å; R385-K388 WeakPolarHBondContact O-CB 3.25Å; R385-K388 PolarHBondContact O-N 3.31Å; R385-A389 PolarHBondContact O-N 3.19Å
386H98.5Very high97.8Very high0 Ų043 Ų430%021%0.212CC..Hα-helixtrans-55.5-53.1177.7-162.5163.1000111.3V318 V319 W322 D342 Y354 S382 L383 K388 A389 I390 F407V318-H386 VanDerWaalsContact CG1-CE1 3.41Å; V318-H386 WeakPolarHBondContact CG1-CE1 3.23Å; V319-H386 HydrophobicContact CG2-CB 3.72Å; W322-H386 AromaticContact CD1-CD2 3.28Å; W322-H386 AromaticContact CD1-NE2 3.11Å; W322-H386 AromaticContact NE1-CD2 3.61Å; W322-H386 AromaticContact NE1-NE2 3.01Å; W322-H386 PolarHBondContact NE1-NE2 3.43Å; D342-H386 IonicContact OD2-CE1 3.93Å; D342-H386 PolarHBondContact OD2-CE1 3.44Å; Y354-H386 PolarHBondContact OH-ND1 3.49Å; Y354-H386 VanDerWaalsContact OH-ND1 3.17Å; S382-H386 WeakPolarHBondContact O-CB 3.37Å; S382-H386 PolarHBondContact O-N 2.99Å; L383-H386 WeakPolarHBondContact O-CB 3.46Å; L383-H386 PolarHBondContact O-N 2.94Å; H386-K388 VanDerWaalsContact C-N 3.35Å; H386-K388 PolarHBondContact O-N 3.43Å; H386-A389 PolarHBondContact O-N 2.91Å; H386-I390 WeakPolarHBondContact CD2-CD1 3.08Å; H386-I390 WeakPolarHBondContact O-CG1 3.43Å; H386-I390 PolarHBondContact O-N 2.72Å; H386-F407 HydrophobicContact CB-CE2 4.49Å; H386-F407 HydrophobicContact CB-CZ 4.45Å; H386-F407 AromaticContact CD2-CZ 3.99Å; H386-F407 AromaticContact CE1-CE2 3.74Å; H386-F407 AromaticContact CE1-CZ 3.89Å; H386-F407 AromaticContact CG-CE2 3.94Å; H386-F407 AromaticContact CG-CZ 3.86Å; H386-F407 AromaticContact ND1-CE2 3.5Å; H386-F407 WeakPolarHBondContact ND1-CE2 3.34Å; H386-F407 AromaticContact ND1-CZ 3.82Å
387I98.4Very high97.9Very high1 Ų142 Ų421%0.00522%0.223CC..Hα-helixtrans-64.5-38.1178.4-70-61.1000112.1L383 R385 A389 I390 N391 F407 L408 A411 A416 V418L383-I387 PolarHBondContact O-N 2.74Å; R385-I387 PolarHBondContact O-N 3.45Å; I387-A389 VanDerWaalsContact C-N 3.3Å; I387-A389 PolarHBondContact O-N 3.17Å; I387-I390 HydrophobicContact CD1-CD1 4.44Å; I387-I390 PolarHBondContact O-N 2.92Å; I387-N391 WeakPolarHBondContact O-CB 3.33Å; I387-N391 VanDerWaalsContact O-CG 3.26Å; I387-N391 PolarHBondContact O-N 3.07Å; I387-N391 PolarHBondContact O-OD1 3.2Å; I387-F407 HydrophobicContact CD1-CD1 4.39Å; I387-F407 HydrophobicContact CD1-CE1 3.35Å; I387-F407 HydrophobicContact CD1-CE2 4.44Å; I387-F407 HydrophobicContact CD1-CZ 3.39Å; I387-F407 HydrophobicContact CG1-CE1 4.44Å; I387-F407 HydrophobicContact CG1-CZ 4.04Å; I387-L408 HydrophobicContact CD1-CD2 4.04Å; I387-A411 HydrophobicContact CD1-CB 4.27Å; I387-A411 HydrophobicContact CG1-CB 3.79Å; I387-A416 HydrophobicContact CB-CB 3.92Å; I387-A416 HydrophobicContact CG1-CB 3.87Å; I387-A416 HydrophobicContact CG2-CB 4.1Å; I387-V418 HydrophobicContact CB-CG1 4.3Å; I387-V418 HydrophobicContact CD1-CG1 3.53Å; I387-V418 HydrophobicContact CG1-CG1 3.63Å; I387-V418 HydrophobicContact CG2-CG1 3.71Å
388K98.4Very high98Very high142 Ų14239 Ų3962%0.61720%0.201SC*.Hα-helixtrans-57.6-43.6178.5-174.9-179.1179.1-177.30112R384 R385 H386 K392R384-K388 WeakPolarHBondContact O-CB 3.2Å; R384-K388 PolarHBondContact O-N 3.16Å; R385-K388 WeakPolarHBondContact O-CB 3.25Å; R385-K388 PolarHBondContact O-N 3.31Å; H386-K388 VanDerWaalsContact C-N 3.35Å; H386-K388 PolarHBondContact O-N 3.43Å; K388-K392 WeakPolarHBondContact O-CG 3.48Å; K388-K392 PolarHBondContact O-N 2.75Å
389A98.5Very high98Very high3 Ų339.5 Ų39.53%0.02520%0.201CC..Hα-helixtrans-67.6-43.7177.500000112W322 E323 L326 R385 H386 I387 N391 K392 L393W322-A389 HydrophobicContact CB-CB 3.8Å; E323-A389 HydrophobicContact CG-CB 4.26Å; L326-A389 HydrophobicContact CD2-CB 4.49Å; R385-A389 PolarHBondContact O-N 3.19Å; H386-A389 PolarHBondContact O-N 2.91Å; I387-A389 VanDerWaalsContact C-N 3.3Å; I387-A389 PolarHBondContact O-N 3.17Å; A389-N391 PolarHBondContact O-N 3.02Å; A389-K392 PolarHBondContact O-N 3.42Å; A389-L393 PolarHBondContact O-N 3.34Å
390I98.5Very high98Very high0 Ų039.5 Ų39.50%020%0.201CC..Hα-helixtrans-59.5-44.8175.4-70.1164.6000111.2W322 H386 I387 K392 L393 S394 M398 F400 F407 Y430W322-I390 HydrophobicContact CD2-CG1 4.24Å; W322-I390 HydrophobicContact CG-CG1 4.45Å; H386-I390 WeakPolarHBondContact CD2-CD1 3.08Å; H386-I390 WeakPolarHBondContact O-CG1 3.43Å; H386-I390 PolarHBondContact O-N 2.72Å; I387-I390 HydrophobicContact CD1-CD1 4.44Å; I387-I390 PolarHBondContact O-N 2.92Å; I390-K392 VanDerWaalsContact C-N 3.35Å; I390-K392 PolarHBondContact O-N 2.98Å; I390-L393 PolarHBondContact O-N 2.83Å; I390-S394 WeakPolarHBondContact O-CB 3.5Å; I390-S394 PolarHBondContact O-N 2.92Å; I390-M398 HydrophobicContact CG2-CE 4.14Å; I390-F400 HydrophobicContact CD1-CD2 3.97Å; I390-F400 HydrophobicContact CD1-CE1 4.33Å; I390-F400 HydrophobicContact CD1-CE2 3.44Å; I390-F400 VanDerWaalsContact CD1-CE2 3.44Å; I390-F400 HydrophobicContact CD1-CZ 3.66Å; I390-F400 HydrophobicContact CG1-CD2 4.1Å; I390-F400 HydrophobicContact CG1-CE2 4.05Å; I390-F400 HydrophobicContact CG2-CB 3.84Å; I390-F400 HydrophobicContact CG2-CD1 3.96Å; I390-F400 HydrophobicContact CG2-CD2 3.71Å; I390-F400 HydrophobicContact CG2-CE2 4.27Å; I390-F400 HydrophobicContact CG2-CG 3.55Å; I390-F407 HydrophobicContact CD1-CE1 4Å; I390-F407 HydrophobicContact CD1-CZ 3.94Å; I390-Y430 HydrophobicContact CG2-CD2 4.46Å; I390-Y430 HydrophobicContact CG2-CE1 4.47Å; I390-Y430 HydrophobicContact CG2-CE2 3.76Å
391N98.3Very high97.9Very high7 Ų737.5 Ų37.54%0.03719%0.192CC..Hα-helixtrans-53.8-50.7176.9-76.2-2.3000111.3I387 A389 S394 D395 E417 Y430I387-N391 WeakPolarHBondContact O-CB 3.33Å; I387-N391 VanDerWaalsContact O-CG 3.26Å; I387-N391 PolarHBondContact O-N 3.07Å; I387-N391 PolarHBondContact O-OD1 3.2Å; A389-N391 PolarHBondContact O-N 3.02Å; N391-S394 PolarHBondContact O-N 3.28Å; N391-D395 WeakPolarHBondContact O-CB 3.44Å; N391-D395 PolarHBondContact O-N 3.27Å; N391-E417 PolarHBondContact ND2-O 3.27Å; N391-Y430 WeakPolarHBondContact CA-OH 3.41Å; N391-Y430 WeakPolarHBondContact OD1-CE2 3.11Å; N391-Y430 PolarHBondContact OD1-OH 3.25Å
392K98.3Very high97.7Very high111 Ų11134 Ų3448%0.48318%0.176SC..Hα-helixtrans-66.4-43.1-179.1-68.1-66.2-175.5-177.40113.4L326 K388 A389 I390 S394 A396L326-K392 HydrophobicContact CD1-CB 3.55Å; L326-K392 HydrophobicContact CD1-CG 4.43Å; L326-K392 HydrophobicContact CD2-CB 3.91Å; L326-K392 HydrophobicContact CD2-CG 4.17Å; L326-K392 HydrophobicContact CG-CB 4.39Å; K388-K392 WeakPolarHBondContact O-CG 3.48Å; K388-K392 PolarHBondContact O-N 2.75Å; A389-K392 PolarHBondContact O-N 3.42Å; I390-K392 VanDerWaalsContact C-N 3.35Å; I390-K392 PolarHBondContact O-N 2.98Å; K392-S394 VanDerWaalsContact C-N 3.31Å; K392-A396 PolarHBondContact O-N 3.47Å
393L98.6Very high97.4Very high2 Ų234.7 Ų34.71%0.0118%0.178CC..Hα-helixtrans-67.7-35177.4-74168.8000111.9W322 L325 L326 F329 L335 A389 I390 A396 G397 M398W322-L393 HydrophobicContact CE3-CD1 3.54Å; W322-L393 HydrophobicContact CZ3-CD1 3.99Å; L325-L393 HydrophobicContact CB-CD1 4.05Å; L326-L393 HydrophobicContact CB-CD1 4.46Å; L326-L393 HydrophobicContact CB-CD2 4.39Å; L326-L393 HydrophobicContact CB-CG 4.25Å; L326-L393 HydrophobicContact CD1-CD2 4.45Å; L326-L393 HydrophobicContact CD1-CG 4.43Å; F329-L393 HydrophobicContact CB-CD2 4.32Å; L335-L393 HydrophobicContact CD1-CD2 3.99Å; A389-L393 PolarHBondContact O-N 3.34Å; I390-L393 PolarHBondContact O-N 2.83Å; L393-A396 WeakPolarHBondContact O-CB 3.24Å; L393-A396 PolarHBondContact O-N 2.89Å; L393-G397 PolarHBondContact O-N 3.41Å; L393-M398 HydrophobicContact CB-CB 4.28Å; L393-M398 HydrophobicContact CB-CE 3.74Å; L393-M398 HydrophobicContact CB-SD 3.99Å; L393-M398 HydrophobicContact CD1-SD 4.47Å; L393-M398 VanDerWaalsContact O-CB 3.25Å; L393-M398 WeakPolarHBondContact O-CB 3.42Å; L393-M398 PolarHBondContact O-N 2.76Å
394S97.5Very high97Very high27 Ų2734.8 Ų34.819%0.18918%0.179CC..Hα-helixtrans-71.7-39178.1-168.60000112.4I390 N391 K392 A396 G397 M398 Y430I390-S394 WeakPolarHBondContact O-CB 3.5Å; I390-S394 PolarHBondContact O-N 2.92Å; N391-S394 PolarHBondContact O-N 3.28Å; K392-S394 VanDerWaalsContact C-N 3.31Å; S394-A396 PolarHBondContact O-N 2.75Å; S394-G397 PolarHBondContact O-N 2.87Å; S394-M398 WeakPolarHBondContact CA-O 3.16Å; S394-M398 WeakPolarHBondContact CB-O 3.33Å; S394-M398 PolarHBondContact OG-O 2.85Å; S394-Y430 WeakPolarHBondContact CB-OH 3.46Å; S394-Y430 WeakPolarHBondContact OG-CE1 3.41Å
395D97Very high96.5Very high110 Ų11030.9 Ų30.959%0.58817%0.165SC*.Hα-helixtrans-60.6-25170.9-69.2-20.3000112.2N391 R429N391-D395 WeakPolarHBondContact O-CB 3.44Å; N391-D395 PolarHBondContact O-N 3.27Å; D395-R429 IonicContact OD1-CZ 3.54Å; D395-R429 IonicContact OD1-NH2 2.67Å; D395-R429 PolarHBondContact OD1-NH2 3.07Å; D395-R429 IonicContact OD2-NH2 3.73Å; D395-R429 PolarHBondContact OD2-NH2 2.97Å; D395-R429 VanDerWaalsContact OD2-NH2 3.09Å
396A97.2Very high96.1Very high33 Ų3327.6 Ų27.627%0.27316%0.155SC..THydrogen-bonded Turntrans-84.1-4.3174.100000114.6F329 L335 K392 L393 S394F329-A396 HydrophobicContact CD1-CB 4.09Å; F329-A396 HydrophobicContact CD2-CB 4.44Å; F329-A396 HydrophobicContact CE1-CB 3.44Å; F329-A396 VanDerWaalsContact CE1-CB 3.44Å; F329-A396 HydrophobicContact CE2-CB 3.86Å; F329-A396 HydrophobicContact CZ-CB 3.31Å; L335-A396 HydrophobicContact CD1-CB 4.29Å; K392-A396 PolarHBondContact O-N 3.47Å; L393-A396 WeakPolarHBondContact O-CB 3.24Å; L393-A396 PolarHBondContact O-N 2.89Å; S394-A396 PolarHBondContact O-N 2.75Å
397G96.6Very high96Very high57 Ų5727.6 Ų27.659%0.58816%0.155SC*.THydrogen-bonded Turntrans112.91.9176.400000115.7L393 S394L393-G397 PolarHBondContact O-N 3.41Å; S394-G397 PolarHBondContact O-N 2.87Å
398M98Very high95.8Very high3 Ų327.7 Ų27.72%0.01516%0.155CC..  trans-70136.2169.3-178.4-16667.800110W322 L335 V337 I390 L393 S394 F400W322-M398 HydrophobicContact CE3-SD 4.43Å; W322-M398 HydrophobicContact CH2-CE 4.38Å; W322-M398 HydrophobicContact CH2-SD 3.7Å; W322-M398 HydrophobicContact CZ3-CE 4.19Å; W322-M398 HydrophobicContact CZ3-SD 3.4Å; W322-M398 WeakPolarHBondContact CZ3-SD 3.49Å; L335-M398 HydrophobicContact CD1-CB 4.46Å; V337-M398 HydrophobicContact CB-SD 4.35Å; V337-M398 HydrophobicContact CG1-CB 4.39Å; V337-M398 HydrophobicContact CG1-CG 3.98Å; V337-M398 HydrophobicContact CG1-SD 3.59Å; V337-M398 VanDerWaalsContact CG1-SD 3.59Å; V337-M398 HydrophobicContact CG2-CG 4.04Å; V337-M398 HydrophobicContact CG2-SD 3.81Å; I390-M398 HydrophobicContact CG2-CE 4.14Å; L393-M398 HydrophobicContact CB-CB 4.28Å; L393-M398 HydrophobicContact CB-CE 3.74Å; L393-M398 HydrophobicContact CB-SD 3.99Å; L393-M398 HydrophobicContact CD1-SD 4.47Å; L393-M398 VanDerWaalsContact O-CB 3.25Å; L393-M398 WeakPolarHBondContact O-CB 3.42Å; L393-M398 PolarHBondContact O-N 2.76Å; S394-M398 WeakPolarHBondContact CA-O 3.16Å; S394-M398 WeakPolarHBondContact CB-O 3.33Å; S394-M398 PolarHBondContact OG-O 2.85Å; M398-F400 HydrophobicContact CE-CB 4.07Å; M398-F400 HydrophobicContact CE-CD2 4.41Å
399F97.6Very high95.6Very high42 Ų4221.3 Ų21.318%0.18413%0.128CC..EExtended strand (participates in β ladder)trans-93.3123.4170.8-172.2-93.4000111.4Y233 D338 L339 G340 W401 P431Y233-F399 HydrophobicContact CD1-CD1 4.18Å; Y233-F399 AromaticContact CD1-CD2 3.51Å; Y233-F399 HydrophobicContact CD1-CD2 3.51Å; Y233-F399 HydrophobicContact CD1-CE1 4.12Å; Y233-F399 AromaticContact CD1-CE2 3.42Å; Y233-F399 HydrophobicContact CD1-CE2 3.42Å; Y233-F399 VanDerWaalsContact CD1-CE2 3.42Å; Y233-F399 AromaticContact CD1-CG 3.91Å; Y233-F399 HydrophobicContact CD1-CG 3.91Å; Y233-F399 AromaticContact CD1-CZ 3.77Å; Y233-F399 HydrophobicContact CD1-CZ 3.77Å; Y233-F399 AromaticContact CD2-CD1 3.37Å; Y233-F399 HydrophobicContact CD2-CD1 3.37Å; Y233-F399 HydrophobicContact CD2-CD2 4.24Å; Y233-F399 AromaticContact CD2-CE1 3.35Å; Y233-F399 HydrophobicContact CD2-CE1 3.35Å; Y233-F399 HydrophobicContact CD2-CE2 4.22Å; Y233-F399 AromaticContact CD2-CG 3.85Å; Y233-F399 HydrophobicContact CD2-CG 3.85Å; Y233-F399 AromaticContact CD2-CZ 3.82Å; Y233-F399 HydrophobicContact CD2-CZ 3.82Å; Y233-F399 HydrophobicContact CE1-CD1 4.43Å; Y233-F399 AromaticContact CE1-CD2 3.84Å; Y233-F399 HydrophobicContact CE1-CD2 3.84Å; Y233-F399 AromaticContact CE1-CE1 3.9Å; Y233-F399 HydrophobicContact CE1-CE1 3.9Å; Y233-F399 AromaticContact CE1-CE2 3.21Å; Y233-F399 HydrophobicContact CE1-CE2 3.21Å; Y233-F399 HydrophobicContact CE1-CG 4.41Å; Y233-F399 AromaticContact CE1-CZ 3.27Å; Y233-F399 HydrophobicContact CE1-CZ 3.27Å; Y233-F399 AromaticContact CE2-CD1 3.67Å; Y233-F399 HydrophobicContact CE2-CD1 3.67Å; Y233-F399 AromaticContact CE2-CE1 3.08Å; Y233-F399 HydrophobicContact CE2-CE1 3.08Å; Y233-F399 HydrophobicContact CE2-CE2 4.06Å; Y233-F399 HydrophobicContact CE2-CG 4.37Å; Y233-F399 AromaticContact CE2-CZ 3.33Å; Y233-F399 HydrophobicContact CE2-CZ 3.33Å; Y233-F399 HydrophobicContact CG-CB 4.38Å; Y233-F399 AromaticContact CG-CD1 3.64Å; Y233-F399 HydrophobicContact CG-CD1 3.64Å; Y233-F399 AromaticContact CG-CD2 3.71Å; Y233-F399 HydrophobicContact CG-CD2 3.71Å; Y233-F399 AromaticContact CG-CE1 3.85Å; Y233-F399 HydrophobicContact CG-CE1 3.85Å; Y233-F399 AromaticContact CG-CE2 3.92Å; Y233-F399 HydrophobicContact CG-CE2 3.92Å; Y233-F399 AromaticContact CG-CG 3.58Å; Y233-F399 HydrophobicContact CG-CG 3.58Å; Y233-F399 AromaticContact CG-CZ 4Å; Y233-F399 HydrophobicContact CG-CZ 4Å; Y233-F399 AromaticContact CZ-CE1 3.36Å; Y233-F399 AromaticContact CZ-CE2 3.53Å; Y233-F399 AromaticContact CZ-CZ 2.99Å; Y233-F399 VanDerWaalsContact OH-CZ 3.23Å; Y233-F399 WeakPolarHBondContact OH-CZ 3.44Å; D338-F399 PolarHBondContact O-N 3.29Å; L339-F399 CarbonylContact C-O 3.59Å; L339-F399 WeakPolarHBondContact CA-O 3.04Å; L339-F399 HydrophobicContact CD2-CB 4.13Å; L339-F399 HydrophobicContact CD2-CD1 4.42Å; G340-F399 PolarHBondContact N-O 3.5Å; F399-W401 AromaticContact CD1-CE3 3.92Å; F399-W401 HydrophobicContact CD1-CE3 3.92Å; F399-W401 HydrophobicContact CD1-CZ3 4.49Å; F399-W401 HydrophobicContact CE1-CB 4.1Å; F399-W401 HydrophobicContact CE1-CE3 4.02Å; F399-P431 HydrophobicContact CZ-CG 3.72Å
400F97.5Very high95.4Very high0 Ų021.5 Ų21.50%013%0.128CC..EExtended strand (participates in β ladder)trans-113.1143.4176.4-172.5-90.5000112.1W322 G340 S341 D342 I390 M398 F407 Y430W322-F400 HydrophobicContact CZ2-CD2 4.43Å; W322-F400 HydrophobicContact CZ2-CE2 4.24Å; G340-F400 VanDerWaalsContact C-CD2 3.45Å; G340-F400 VanDerWaalsContact O-CA 3.31Å; G340-F400 WeakPolarHBondContact O-CA 3.48Å; G340-F400 WeakPolarHBondContact O-CD2 3.15Å; S341-F400 VanDerWaalsContact CA-CE2 3.48Å; D342-F400 HydrophobicContact CB-CZ 4.34Å; I390-F400 HydrophobicContact CD1-CD2 3.97Å; I390-F400 HydrophobicContact CD1-CE1 4.33Å; I390-F400 HydrophobicContact CD1-CE2 3.44Å; I390-F400 VanDerWaalsContact CD1-CE2 3.44Å; I390-F400 HydrophobicContact CD1-CZ 3.66Å; I390-F400 HydrophobicContact CG1-CD2 4.1Å; I390-F400 HydrophobicContact CG1-CE2 4.05Å; I390-F400 HydrophobicContact CG2-CB 3.84Å; I390-F400 HydrophobicContact CG2-CD1 3.96Å; I390-F400 HydrophobicContact CG2-CD2 3.71Å; I390-F400 HydrophobicContact CG2-CE2 4.27Å; I390-F400 HydrophobicContact CG2-CG 3.55Å; M398-F400 HydrophobicContact CE-CB 4.07Å; M398-F400 HydrophobicContact CE-CD2 4.41Å; F400-F407 HydrophobicContact CE1-CD1 4.12Å; F400-F407 AromaticContact CE1-CE1 3.88Å; F400-F407 HydrophobicContact CE1-CE1 3.88Å; F400-F407 HydrophobicContact CZ-CD1 4Å; F400-F407 AromaticContact CZ-CE1 3.64Å; F400-F407 HydrophobicContact CZ-CE1 3.64Å; F400-Y430 HydrophobicContact CB-CD1 3.9Å; F400-Y430 HydrophobicContact CB-CE1 4.1Å; F400-Y430 HydrophobicContact CB-CG 4.3Å; F400-Y430 HydrophobicContact CD1-CD1 4.2Å; F400-Y430 AromaticContact CD1-CD2 3.9Å; F400-Y430 HydrophobicContact CD1-CD2 3.9Å; F400-Y430 AromaticContact CD1-CG 3.72Å; F400-Y430 HydrophobicContact CD1-CG 3.72Å; F400-Y430 HydrophobicContact CG-CG 4.46Å
401W96Very high95.3Very high1 Ų121.5 Ų21.50%0.00413%0.128CC..  trans-139152.2169.471.886.9000112.9T225 A229 F244 L339 G340 S341 F399 Y403 P431 Y433T225-W401 HydrophobicContact CG2-CZ2 4.19Å; A229-W401 HydrophobicContact CB-CH2 4.36Å; A229-W401 HydrophobicContact CB-CZ3 4.25Å; F244-W401 AromaticContact CD2-CH2 3.68Å; F244-W401 HydrophobicContact CD2-CH2 3.68Å; F244-W401 HydrophobicContact CD2-CZ2 4.34Å; F244-W401 HydrophobicContact CD2-CZ3 4.47Å; F244-W401 AromaticContact CE2-CH2 3.33Å; F244-W401 HydrophobicContact CE2-CH2 3.33Å; F244-W401 AromaticContact CE2-CZ2 3.56Å; F244-W401 HydrophobicContact CE2-CZ2 3.56Å; F244-W401 HydrophobicContact CE2-CZ3 4.29Å; F244-W401 HydrophobicContact CZ-CH2 4.15Å; F244-W401 AromaticContact CZ-CZ2 3.99Å; F244-W401 HydrophobicContact CZ-CZ2 3.99Å; L339-W401 HydrophobicContact CB-CH2 4.14Å; L339-W401 HydrophobicContact CB-CZ3 3.81Å; L339-W401 HydrophobicContact CD2-CZ3 4.09Å; L339-W401 HydrophobicContact CG-CZ3 4.34Å; G340-W401 WeakPolarHBondContact O-CZ3 3.31Å; G340-W401 PolarHBondContact O-N 3.41Å; G340-W401 VanDerWaalsContact O-N 3.1Å; S341-W401 WeakPolarHBondContact CA-O 3.45Å; S341-W401 WeakPolarHBondContact CB-O 3.49Å; S341-W401 PolarHBondContact OG-NE1 2.88Å; S341-W401 PolarHBondContact OG-O 2.86Å; F399-W401 AromaticContact CD1-CE3 3.92Å; F399-W401 HydrophobicContact CD1-CE3 3.92Å; F399-W401 HydrophobicContact CD1-CZ3 4.49Å; F399-W401 HydrophobicContact CE1-CB 4.1Å; F399-W401 HydrophobicContact CE1-CE3 4.02Å; W401-Y403 HydrophobicContact CZ2-CE2 4.42Å; W401-Y403 AromaticContact NE1-CD2 3.27Å; W401-Y403 VanDerWaalsContact NE1-CD2 3.27Å; W401-Y403 AromaticContact NE1-CE2 3.64Å; W401-P431 VanDerWaalsContact CA-O 3.31Å; W401-P431 WeakPolarHBondContact CA-O 3.27Å; W401-P431 WeakPolarHBondContact CB-O 3.24Å; W401-Y433 VanDerWaalsContact CD1-CB 3.47Å
402D93.9Very high95.1Very high9 Ų924.7 Ų24.75%0.04814%0.142CC..BIsolated β-bridgetrans-79.4131.5171.2-176.8-73.8000111G404 F407 L408 P431 S432 Y433D402-G404 PolarHBondContact O-N 3.47Å; D402-G404 VanDerWaalsContact OD1-CA 3.25Å; D402-G404 WeakPolarHBondContact OD1-CA 3.22Å; D402-G404 PolarHBondContact OD1-N 3.43Å; D402-F407 WeakPolarHBondContact OD2-CB 3.25Å; D402-F407 PolarHBondContact OD2-N 2.93Å; D402-L408 HydrophobicContact CB-CD1 3.57Å; D402-L408 HydrophobicContact CB-CG 3.79Å; D402-L408 WeakPolarHBondContact OD2-CG 3.45Å; D402-L408 PolarHBondContact OD2-N 3.35Å; D402-P431 PolarHBondContact N-O 3.32Å; D402-S432 CarbonylContact O-C 3.59Å; D402-S432 WeakPolarHBondContact O-CA 3.4Å; D402-Y433 PolarHBondContact O-N 3.15Å
403Y92.1Very high95Very high14 Ų1425 Ų256%0.05514%0.14CC..  trans-8714.4-176.5-143.5-85.8000113.7T222 T225 S341 D342 Q343 W401 Y433T222-Y403 WeakPolarHBondContact CA-OH 3.29Å; T222-Y403 VanDerWaalsContact CB-OH 3.23Å; T222-Y403 WeakPolarHBondContact CB-OH 3.4Å; T222-Y403 HydrophobicContact CG2-CE2 4.41Å; T222-Y403 WeakPolarHBondContact CG2-OH 3.48Å; T222-Y403 PolarHBondContact OG1-OH 3.39Å; T225-Y403 HydrophobicContact CG2-CE2 3.92Å; S341-Y403 WeakPolarHBondContact OG-CD2 3.4Å; D342-Y403 WeakPolarHBondContact O-CB 3.17Å; Q343-Y403 HydrophobicContact CG-CD1 4.04Å; Q343-Y403 HydrophobicContact CG-CG 4.38Å; Q343-Y403 VanDerWaalsContact OE1-CD1 3.3Å; W401-Y403 HydrophobicContact CZ2-CE2 4.42Å; W401-Y403 AromaticContact NE1-CD2 3.27Å; W401-Y403 VanDerWaalsContact NE1-CD2 3.27Å; W401-Y403 AromaticContact NE1-CE2 3.64Å; Y403-Y433 VanDerWaalsContact O-CE1 3.29Å; Y403-Y433 WeakPolarHBondContact O-CE1 3.31Å
404G88.3Confident94.8Very high2 Ų225 Ų252%0.02114%0.142CC..SBendtrans73.731.3-176.800000113.2D402 R555D402-G404 PolarHBondContact O-N 3.47Å; D402-G404 VanDerWaalsContact OD1-CA 3.25Å; D402-G404 WeakPolarHBondContact OD1-CA 3.22Å; D402-G404 PolarHBondContact OD1-N 3.43Å; G404-R555 VanDerWaalsContact CA-CD 3.49Å; G404-R555 WeakPolarHBondContact O-CD 3.17Å; G404-R555 PolarHBondContact O-NH1 3.26Å
405N88.4Confident94.8Very high10 Ų1026.5 Ų26.55%0.05316%0.161CC..SBendtrans-101.99.7177.765.8-31.6000113D342 T344 L346 H347 F407D342-N405 PolarHBondContact O-ND2 3.14Å; D342-N405 PolarHBondContact OD1-ND2 3.5Å; T344-N405 PolarHBondContact N-ND2 2.82Å; T344-N405 WeakPolarHBondContact O-CB 3.35Å; T344-N405 PolarHBondContact O-ND2 3.13Å; L346-N405 CarbonylContact C-O 3.59Å; L346-N405 WeakPolarHBondContact CA-O 3.25Å; L346-N405 WeakPolarHBondContact CB-O 3.46Å; L346-N405 PolarHBondContact N-O 2.97Å; H347-N405 PolarHBondContact N-O 3.18Å; N405-F407 VanDerWaalsContact C-N 3.3Å; N405-F407 WeakPolarHBondContact OD1-CB 3.46Å; N405-F407 PolarHBondContact OD1-N 3.13Å
406A91.4Very high94.7Very high6 Ų621.8 Ų21.85%0.0514%0.137CC..SBendtrans68.520.8-171.900000114.4L346 L409 E410 V594L346-A406 HydrophobicContact CB-CB 4.46Å; A406-L409 HydrophobicContact CB-CB 4.39Å; A406-L409 PolarHBondContact O-N 3.31Å; A406-E410 WeakPolarHBondContact O-CB 3.38Å; A406-E410 PolarHBondContact O-N 2.69Å; A406-V594 HydrophobicContact CB-CG1 3.88Å
407F95.1Very high94.6Very high0 Ų027.2 Ų27.20%016%0.157CC..Hα-helixtrans-61.5-52.3-178.2170.1-110.5000112.6D342 L346 L383 H386 I387 I390 F400 D402 N405 L409 E410 A411D342-F407 HydrophobicContact CB-CD1 4.32Å; D342-F407 HydrophobicContact CB-CD2 4.49Å; D342-F407 HydrophobicContact CB-CG 4.24Å; L346-F407 HydrophobicContact CG-CB 4.41Å; L346-F407 HydrophobicContact CG-CD2 4.37Å; L383-F407 HydrophobicContact CD2-CD2 4.04Å; L383-F407 HydrophobicContact CD2-CE2 3.84Å; H386-F407 HydrophobicContact CB-CE2 4.49Å; H386-F407 HydrophobicContact CB-CZ 4.45Å; H386-F407 AromaticContact CD2-CZ 3.99Å; H386-F407 AromaticContact CE1-CE2 3.74Å; H386-F407 AromaticContact CE1-CZ 3.89Å; H386-F407 AromaticContact CG-CE2 3.94Å; H386-F407 AromaticContact CG-CZ 3.86Å; H386-F407 AromaticContact ND1-CE2 3.5Å; H386-F407 WeakPolarHBondContact ND1-CE2 3.34Å; H386-F407 AromaticContact ND1-CZ 3.82Å; I387-F407 HydrophobicContact CD1-CD1 4.39Å; I387-F407 HydrophobicContact CD1-CE1 3.35Å; I387-F407 HydrophobicContact CD1-CE2 4.44Å; I387-F407 HydrophobicContact CD1-CZ 3.39Å; I387-F407 HydrophobicContact CG1-CE1 4.44Å; I387-F407 HydrophobicContact CG1-CZ 4.04Å; I390-F407 HydrophobicContact CD1-CE1 4Å; I390-F407 HydrophobicContact CD1-CZ 3.94Å; F400-F407 HydrophobicContact CE1-CD1 4.12Å; F400-F407 AromaticContact CE1-CE1 3.88Å; F400-F407 HydrophobicContact CE1-CE1 3.88Å; F400-F407 HydrophobicContact CZ-CD1 4Å; F400-F407 AromaticContact CZ-CE1 3.64Å; F400-F407 HydrophobicContact CZ-CE1 3.64Å; D402-F407 WeakPolarHBondContact OD2-CB 3.25Å; D402-F407 PolarHBondContact OD2-N 2.93Å; N405-F407 VanDerWaalsContact C-N 3.3Å; N405-F407 WeakPolarHBondContact OD1-CB 3.46Å; N405-F407 PolarHBondContact OD1-N 3.13Å; F407-L409 VanDerWaalsContact C-N 3.3Å; F407-L409 PolarHBondContact O-N 3.26Å; F407-E410 PolarHBondContact O-N 3.3Å; F407-A411 WeakPolarHBondContact O-CB 3.31Å; F407-A411 PolarHBondContact O-N 3.43Å
408L94.8Very high94.4Very high2 Ų224.5 Ų24.51%0.0113%0.129CC..Hα-helixtrans-66.2-34.5178.8-62.5178.1000112.3I387 D402 A411 Q412 V418 F428 Y430I387-L408 HydrophobicContact CD1-CD2 4.04Å; D402-L408 HydrophobicContact CB-CD1 3.57Å; D402-L408 HydrophobicContact CB-CG 3.79Å; D402-L408 WeakPolarHBondContact OD2-CG 3.45Å; D402-L408 PolarHBondContact OD2-N 3.35Å; L408-A411 PolarHBondContact O-N 3Å; L408-Q412 WeakPolarHBondContact O-CB 3.49Å; L408-Q412 PolarHBondContact O-N 3.11Å; L408-V418 HydrophobicContact CD2-CB 4.32Å; L408-V418 HydrophobicContact CD2-CG1 3.94Å; L408-F428 HydrophobicContact CB-CB 4.38Å; L408-F428 HydrophobicContact CB-CD1 4.1Å; L408-F428 HydrophobicContact CB-CD2 3.84Å; L408-F428 HydrophobicContact CB-CE1 4.35Å; L408-F428 HydrophobicContact CB-CE2 4.1Å; L408-F428 HydrophobicContact CB-CG 3.84Å; L408-F428 HydrophobicContact CB-CZ 4.35Å; L408-F428 HydrophobicContact CD1-CB 3.68Å; L408-F428 HydrophobicContact CD1-CD2 3.98Å; L408-F428 HydrophobicContact CD1-CG 3.96Å; L408-Y430 VanDerWaalsContact CD1-O 3.24Å; L408-Y430 WeakPolarHBondContact CD1-O 3.35Å; L408-Y430 HydrophobicContact CD2-CD2 4.09Å
409L93.3Very high94.1Very high9 Ų928 Ų285%0.04715%0.154CC..Hα-helixtrans-65-49.5177.517961000111.7A406 F407 A411 Q412 R413 F428 F554 V594A406-L409 HydrophobicContact CB-CB 4.39Å; A406-L409 PolarHBondContact O-N 3.31Å; F407-L409 VanDerWaalsContact C-N 3.3Å; F407-L409 PolarHBondContact O-N 3.26Å; L409-A411 VanDerWaalsContact C-N 3.35Å; L409-Q412 WeakPolarHBondContact O-CB 3.45Å; L409-Q412 PolarHBondContact O-N 2.89Å; L409-R413 WeakPolarHBondContact O-CG 3.49Å; L409-R413 PolarHBondContact O-N 3.45Å; L409-F428 HydrophobicContact CB-CZ 4.45Å; L409-F554 HydrophobicContact CD1-CE1 4.15Å; L409-F554 HydrophobicContact CD1-CZ 4.05Å; L409-F554 HydrophobicContact CD2-CD2 4.14Å; L409-F554 HydrophobicContact CD2-CE2 4.06Å; L409-F554 HydrophobicContact CD2-CG 4.49Å; L409-F554 HydrophobicContact CD2-CZ 4.35Å; L409-V594 HydrophobicContact CD2-CG1 4.48Å
410E95.1Very high93.6Very high6 Ų631 Ų313%0.02817%0.167CC..Hα-helixtrans-70.2-33.1177.5-70.1-61.214800112R188 L346 P349 L383 A406 F407 R413 A414R188-E410 IonicContact NH1-OE1 3.05Å; L346-E410 HydrophobicContact CB-CG 4.34Å; L346-E410 HydrophobicContact CD1-CB 3.62Å; L346-E410 HydrophobicContact CD1-CG 4.03Å; L346-E410 HydrophobicContact CG-CB 4.45Å; L346-E410 WeakPolarHBondContact O-CG 3.29Å; P349-E410 HydrophobicContact CG-CG 4.15Å; L383-E410 HydrophobicContact CD1-CB 4.29Å; A406-E410 WeakPolarHBondContact O-CB 3.38Å; A406-E410 PolarHBondContact O-N 2.69Å; F407-E410 PolarHBondContact O-N 3.3Å; E410-R413 PolarHBondContact O-N 2.88Å; E410-R413 IonicContact OE1-CZ 3.43Å; E410-R413 IonicContact OE1-NH1 3.82Å; E410-R413 PolarHBondContact OE1-NH1 3.27Å; E410-A414 WeakPolarHBondContact O-CB 3.02Å; E410-A414 PolarHBondContact O-N 2.98Å
411A96.4Very high92.9Very high0 Ų038.1 Ų38.10%021%0.21CC..Hα-helixtrans-64.1-40.3172.200000111.7I387 F407 L408 L409 A414 G415 A416 V418I387-A411 HydrophobicContact CD1-CB 4.27Å; I387-A411 HydrophobicContact CG1-CB 3.79Å; F407-A411 WeakPolarHBondContact O-CB 3.31Å; F407-A411 PolarHBondContact O-N 3.43Å; L408-A411 PolarHBondContact O-N 3Å; L409-A411 VanDerWaalsContact C-N 3.35Å; A411-A414 CarbonylContact O-C 3.43Å; A411-A414 WeakPolarHBondContact O-CB 3.28Å; A411-A414 PolarHBondContact O-N 3.02Å; A411-G415 PolarHBondContact O-N 2.9Å; A411-A416 HydrophobicContact CB-CB 3.95Å; A411-A416 WeakPolarHBondContact O-CB 3.41Å; A411-A416 PolarHBondContact O-N 3Å; A411-V418 HydrophobicContact CB-CG1 4.01Å
412Q94.9Very high92.1Very high74 Ų7442.2 Ų42.235%0.34625%0.252SS..Hα-helixtrans-61.2-46.9172.5-172.6-17450.700111.1L408 L409 A414 G415 V418 F428L408-Q412 WeakPolarHBondContact O-CB 3.49Å; L408-Q412 PolarHBondContact O-N 3.11Å; L409-Q412 WeakPolarHBondContact O-CB 3.45Å; L409-Q412 PolarHBondContact O-N 2.89Å; Q412-A414 PolarHBondContact O-N 2.96Å; Q412-G415 PolarHBondContact O-N 3.41Å; Q412-V418 HydrophobicContact CB-CG2 3.58Å; Q412-V418 HydrophobicContact CG-CG2 4.23Å; Q412-F428 HydrophobicContact CB-CE1 4.09Å; Q412-F428 HydrophobicContact CG-CE1 4.42Å
413R94.7Very high91.4Very high117 Ų11743 Ų4344%0.44226%0.263SS..Hα-helixtrans-59.5-32.1175.5-70.3170176171.70.2112.2L409 E410 G415 E598L409-R413 WeakPolarHBondContact O-CG 3.49Å; L409-R413 PolarHBondContact O-N 3.45Å; E410-R413 PolarHBondContact O-N 2.88Å; E410-R413 IonicContact OE1-CZ 3.43Å; E410-R413 IonicContact OE1-NH1 3.82Å; E410-R413 PolarHBondContact OE1-NH1 3.27Å; R413-G415 VanDerWaalsContact C-N 3.27Å; R413-G415 PolarHBondContact O-N 3.45Å; R413-E598 IonicContact CZ-OE1 2.71Å; R413-E598 IonicContact NH1-OE1 3.3Å; R413-E598 IonicContact NH2-OE1 3.66Å; R413-E598 PolarHBondContact NH2-OE1 3.04Å
414A96.1Very high90.7Very high4 Ų444.6 Ų44.63%0.03328%0.283CS..THydrogen-bonded Turntrans-78.8-3.3173.700000114.1Q380 L383 R384 E410 A411 Q412Q380-A414 HydrophobicContact CB-CB 3.77Å; Q380-A414 HydrophobicContact CG-CB 3.84Å; L383-A414 HydrophobicContact CB-CB 4.25Å; L383-A414 HydrophobicContact CD1-CB 4.22Å; R384-A414 WeakPolarHBondContact CD-O 3.44Å; R384-A414 PolarHBondContact NH1-O 3.04Å; E410-A414 WeakPolarHBondContact O-CB 3.02Å; E410-A414 PolarHBondContact O-N 2.98Å; A411-A414 CarbonylContact O-C 3.43Å; A411-A414 WeakPolarHBondContact O-CB 3.28Å; A411-A414 PolarHBondContact O-N 3.02Å; Q412-A414 PolarHBondContact O-N 2.96Å
415G95.8Very high90.3Very high58 Ų5848.1 Ų48.160%0.59831%0.312SS*.THydrogen-bonded Turntrans77.824.3-178.400000114.4A411 Q412 R413A411-G415 PolarHBondContact O-N 2.9Å; Q412-G415 PolarHBondContact O-N 3.41Å; R413-G415 VanDerWaalsContact C-N 3.27Å; R413-G415 PolarHBondContact O-N 3.45Å
416A96.1Very high89.8Confident11 Ų1148.5 Ų48.59%0.09132%0.315CS..  trans-75.915417200000111.8R384 I387 A411 V418R384-A416 HydrophobicContact CG-CB 4.23Å; I387-A416 HydrophobicContact CB-CB 3.92Å; I387-A416 HydrophobicContact CG1-CB 3.87Å; I387-A416 HydrophobicContact CG2-CB 4.1Å; A411-A416 HydrophobicContact CB-CB 3.95Å; A411-A416 WeakPolarHBondContact O-CB 3.41Å; A411-A416 PolarHBondContact O-N 3Å; A416-V418 VanDerWaalsContact C-N 3.28Å; A416-V418 HydrophobicContact CB-CG1 4.3Å; A416-V418 PolarHBondContact O-N 3.37Å
417E94.1Very high89.4Confident147 Ų14750.7 Ų50.769%0.68732%0.324SS*.SBendtrans-77.770.7-178.6-65.6178.2175.800112.3N391N391-E417 PolarHBondContact ND2-O 3.27Å
418V93.4Very high89.2Confident0 Ų051.7 Ų51.70%033%0.328CS..  trans-112.5-6.7-178.8-61.70000114I387 L408 A411 Q412 A416 F428 R429I387-V418 HydrophobicContact CB-CG1 4.3Å; I387-V418 HydrophobicContact CD1-CG1 3.53Å; I387-V418 HydrophobicContact CG1-CG1 3.63Å; I387-V418 HydrophobicContact CG2-CG1 3.71Å; L408-V418 HydrophobicContact CD2-CB 4.32Å; L408-V418 HydrophobicContact CD2-CG1 3.94Å; A411-V418 HydrophobicContact CB-CG1 4.01Å; Q412-V418 HydrophobicContact CB-CG2 3.58Å; Q412-V418 HydrophobicContact CG-CG2 4.23Å; A416-V418 VanDerWaalsContact C-N 3.28Å; A416-V418 HydrophobicContact CB-CG1 4.3Å; A416-V418 PolarHBondContact O-N 3.37Å; V418-F428 HydrophobicContact CB-CD1 4.32Å; V418-F428 HydrophobicContact CG2-CD1 3.98Å; V418-F428 HydrophobicContact CG2-CE1 4.33Å; V418-F428 CarbonylContact O-C 3.58Å; V418-F428 VanDerWaalsContact O-CA 3.29Å; V418-F428 WeakPolarHBondContact O-CA 3.46Å; V418-F428 WeakPolarHBondContact O-CB 3.32Å; V418-R429 PolarHBondContact O-N 3.3Å
419S90.2Very high89.1Confident77 Ų7756.1 Ų56.154%0.53835%0.345SS..BIsolated β-bridgetrans-71.9141.8-179.6-58.20000111.8
420K88.4Confident89.1Confident105 Ų10556.1 Ų56.146%0.45734%0.344SS..PPolyproline II helixtrans-88.8133.4171.1-175.5179.2169.6-161.20110.1G422 G423 E427K420-G422 PolarHBondContact O-N 2.87Å; K420-G423 PolarHBondContact O-N 3.33Å; K420-E427 HydrophobicContact CD-CB 4.31Å; K420-E427 WeakPolarHBondContact CD-OE2 3.38Å; K420-E427 IonicContact NZ-OE2 2.7Å; K420-E427 PolarHBondContact NZ-OE2 3.22Å
421V82.6Confident88.9Confident149 Ų14956.4 Ų56.490%0.90335%0.347SS*.THydrogen-bonded Turntrans-63123.5176.2-179.60000109.3G423V421-G423 PolarHBondContact O-N 3.3Å
422G80.3Confident88.6Confident86 Ų8656.7 Ų56.789%0.88735%0.349SS*.THydrogen-bonded Turntrans71.47.4-174.700000114.7K420K420-G422 PolarHBondContact O-N 2.87Å
423G77.4Confident88.3Confident27 Ų2753.6 Ų53.628%0.27833%0.334SS..  trans-76148.8177.300000112.7K420 V421K420-G423 PolarHBondContact O-N 3.33Å; V421-G423 PolarHBondContact O-N 3.3Å
424G78.2Confident87.9Confident46 Ų4648 Ų4847%0.47431%0.313SS..  trans-72.2-177.5171.700000113.6T426 E427G424-T426 PolarHBondContact O-N 3.39Å; G424-T426 VanDerWaalsContact O-N 3.08Å; G424-E427 PolarHBondContact O-N 2.98Å
425A78.8Confident87.4Confident76 Ų7648.6 Ų48.663%0.62832%0.315SS*.THydrogen-bonded Turntrans-60.9-19.9-176.300000115F566A425-F566 HydrophobicContact CB-CZ 4.29Å
426T78Confident86.9Confident18 Ų1848.9 Ų48.911%0.1130%0.301CS..THydrogen-bonded Turntrans-108.62.5179.955.90000113G424 Q435 P553 F554 F566G424-T426 PolarHBondContact O-N 3.39Å; G424-T426 VanDerWaalsContact O-N 3.08Å; T426-Q435 PolarHBondContact O-NE2 3.24Å; T426-P553 HydrophobicContact CG2-CB 3.88Å; T426-F554 HydrophobicContact CG2-CE1 4.31Å; T426-F566 HydrophobicContact CG2-CE1 4.2Å; T426-F566 HydrophobicContact CG2-CE2 3.7Å; T426-F566 HydrophobicContact CG2-CZ 3.36Å
427E83.9Confident86.3Confident53 Ų5348.8 Ų48.825%0.24830%0.298CS..  trans-102113-176-68.2-165.5-162.600112.1K420 G424K420-E427 HydrophobicContact CD-CB 4.31Å; K420-E427 WeakPolarHBondContact CD-OE2 3.38Å; K420-E427 IonicContact NZ-OE2 2.7Å; K420-E427 PolarHBondContact NZ-OE2 3.22Å; G424-E427 PolarHBondContact O-N 2.98Å
428F91Very high86Confident20 Ų2041.8 Ų41.89%0.08827%0.265CS..BIsolated β-bridgetrans-100.8166.5172.9-58.1-71.9000111.2L408 L409 Q412 V418 Y430 F554L408-F428 HydrophobicContact CB-CB 4.38Å; L408-F428 HydrophobicContact CB-CD1 4.1Å; L408-F428 HydrophobicContact CB-CD2 3.84Å; L408-F428 HydrophobicContact CB-CE1 4.35Å; L408-F428 HydrophobicContact CB-CE2 4.1Å; L408-F428 HydrophobicContact CB-CG 3.84Å; L408-F428 HydrophobicContact CB-CZ 4.35Å; L408-F428 HydrophobicContact CD1-CB 3.68Å; L408-F428 HydrophobicContact CD1-CD2 3.98Å; L408-F428 HydrophobicContact CD1-CG 3.96Å; L409-F428 HydrophobicContact CB-CZ 4.45Å; Q412-F428 HydrophobicContact CB-CE1 4.09Å; Q412-F428 HydrophobicContact CG-CE1 4.42Å; V418-F428 HydrophobicContact CB-CD1 4.32Å; V418-F428 HydrophobicContact CG2-CD1 3.98Å; V418-F428 HydrophobicContact CG2-CE1 4.33Å; V418-F428 CarbonylContact O-C 3.58Å; V418-F428 VanDerWaalsContact O-CA 3.29Å; V418-F428 WeakPolarHBondContact O-CA 3.46Å; V418-F428 WeakPolarHBondContact O-CB 3.32Å; F428-Y430 WeakPolarHBondContact CB-O 3.42Å; F428-Y430 PolarHBondContact O-N 3.06Å; F428-F554 HydrophobicContact CE2-CD1 4.06Å; F428-F554 HydrophobicContact CE2-CE1 4.39Å; F428-F554 HydrophobicContact CZ-CD1 4.42Å; F428-F554 HydrophobicContact CZ-CE1 4.35Å
429R92.6Very high85.5Confident96 Ų9641.8 Ų41.836%0.36227%0.265SS..SBendtrans-56.1-33.9173.1-177.6177.8-174.8160.1-0.7111.6D395 V418D395-R429 IonicContact OD1-CZ 3.54Å; D395-R429 IonicContact OD1-NH2 2.67Å; D395-R429 PolarHBondContact OD1-NH2 3.07Å; D395-R429 IonicContact OD2-NH2 3.73Å; D395-R429 PolarHBondContact OD2-NH2 2.97Å; D395-R429 VanDerWaalsContact OD2-NH2 3.09Å; V418-R429 PolarHBondContact O-N 3.3Å
430Y93.6Very high85.4Confident8 Ų840.3 Ų40.33%0.03125%0.252CS..SBendtrans-109.4136.4175.6-55.6-63.1000110I390 N391 S394 F400 L408 F428I390-Y430 HydrophobicContact CG2-CD2 4.46Å; I390-Y430 HydrophobicContact CG2-CE1 4.47Å; I390-Y430 HydrophobicContact CG2-CE2 3.76Å; N391-Y430 WeakPolarHBondContact CA-OH 3.41Å; N391-Y430 WeakPolarHBondContact OD1-CE2 3.11Å; N391-Y430 PolarHBondContact OD1-OH 3.25Å; S394-Y430 WeakPolarHBondContact CB-OH 3.46Å; S394-Y430 WeakPolarHBondContact OG-CE1 3.41Å; F400-Y430 HydrophobicContact CB-CD1 3.9Å; F400-Y430 HydrophobicContact CB-CE1 4.1Å; F400-Y430 HydrophobicContact CB-CG 4.3Å; F400-Y430 HydrophobicContact CD1-CD1 4.2Å; F400-Y430 AromaticContact CD1-CD2 3.9Å; F400-Y430 HydrophobicContact CD1-CD2 3.9Å; F400-Y430 AromaticContact CD1-CG 3.72Å; F400-Y430 HydrophobicContact CD1-CG 3.72Å; F400-Y430 HydrophobicContact CG-CG 4.46Å; L408-Y430 VanDerWaalsContact CD1-O 3.24Å; L408-Y430 WeakPolarHBondContact CD1-O 3.35Å; L408-Y430 HydrophobicContact CD2-CD2 4.09Å; F428-Y430 WeakPolarHBondContact CB-O 3.42Å; F428-Y430 PolarHBondContact O-N 3.06Å
431P91.1Very high85.4Confident13 Ų1335.6 Ų35.68%0.08423%0.231CC..  trans-71.5153.3175.132.6-35.7000110.3F399 W401 D402 Q435 H436F399-P431 HydrophobicContact CZ-CG 3.72Å; W401-P431 VanDerWaalsContact CA-O 3.31Å; W401-P431 WeakPolarHBondContact CA-O 3.27Å; W401-P431 WeakPolarHBondContact CB-O 3.24Å; D402-P431 PolarHBondContact N-O 3.32Å; P431-Q435 VanDerWaalsContact CA-OE1 3.28Å; P431-Q435 HydrophobicContact CB-CB 4.07Å; P431-H436 HydrophobicContact CB-CB 4.21Å; P431-H436 WeakPolarHBondContact CB-ND1 3.1Å; P431-H436 HydrophobicContact CG-CB 4.41Å; P431-H436 WeakPolarHBondContact CG-ND1 3.21Å
432S89.9Confident85.9Confident5 Ų528.5 Ų28.54%0.03519%0.188CC..BIsolated β-bridgetrans-69.2154.9157.490.10000109.9D402 V434 Q435 H436 S558D402-S432 CarbonylContact O-C 3.59Å; D402-S432 WeakPolarHBondContact O-CA 3.4Å; S432-V434 PolarHBondContact O-N 3.12Å; S432-V434 VanDerWaalsContact O-N 3.15Å; S432-V434 PolarHBondContact OG-N 2.76Å; S432-Q435 WeakPolarHBondContact O-CB 3.38Å; S432-Q435 PolarHBondContact O-N 3.47Å; S432-Q435 WeakPolarHBondContact OG-CG 3.44Å; S432-Q435 PolarHBondContact OG-N 2.82Å; S432-Q435 VanDerWaalsContact OG-N 3.07Å; S432-H436 PolarHBondContact O-N 3.3Å; S432-S558 PolarHBondContact OG-OG 3.22Å
433Y89.1Confident86.5Confident10 Ų1024.4 Ų24.44%0.03915%0.146CC..Hα-helixtrans-58.3-27.2173.381.3-70.5000111.5T225 W401 D402 Y403 I437 M438 H545 R555T225-Y433 HydrophobicContact CG2-CD2 4.04Å; T225-Y433 HydrophobicContact CG2-CG 4.36Å; T225-Y433 WeakPolarHBondContact OG1-CD2 3.29Å; W401-Y433 VanDerWaalsContact CD1-CB 3.47Å; D402-Y433 PolarHBondContact O-N 3.15Å; Y403-Y433 VanDerWaalsContact O-CE1 3.29Å; Y403-Y433 WeakPolarHBondContact O-CE1 3.31Å; Y433-I437 CarbonylContact O-C 3.49Å; Y433-I437 VanDerWaalsContact O-CA 3.24Å; Y433-I437 WeakPolarHBondContact O-CA 3.01Å; Y433-I437 WeakPolarHBondContact O-CB 3.19Å; Y433-I437 PolarHBondContact O-N 3.22Å; Y433-M438 HydrophobicContact CD2-CB 4.25Å; Y433-M438 HydrophobicContact CD2-CG 3.3Å; Y433-M438 HydrophobicContact CE2-CB 4.25Å; Y433-M438 HydrophobicContact CE2-CG 3.43Å; Y433-M438 VanDerWaalsContact CE2-CG 3.43Å; Y433-M438 HydrophobicContact CG-CG 4.44Å; Y433-M438 PolarHBondContact O-N 3Å; Y433-H545 AromaticContact CE2-NE2 3.67Å; Y433-H545 AromaticContact CZ-CE1 3.64Å; Y433-H545 AromaticContact CZ-NE2 3.6Å; Y433-H545 PolarHBondContact OH-CE1 3.29Å; Y433-H545 PolarHBondContact OH-ND1 3.09Å; Y433-H545 PolarHBondContact OH-NE2 3.46Å; Y433-R555 PolarHBondContact OH-NH2 3.12Å
434V85.9Confident87.4Confident0 Ų023.4 Ų23.40%013%0.134CC..Iπ-helixtrans-73.4-40.8173.9-173.10000111.3S432 H436 M438 G439 F442 R555S432-V434 PolarHBondContact O-N 3.12Å; S432-V434 VanDerWaalsContact O-N 3.15Å; S432-V434 PolarHBondContact OG-N 2.76Å; V434-H436 VanDerWaalsContact C-N 3.3Å; V434-H436 PolarHBondContact O-N 3.06Å; V434-M438 HydrophobicContact CG2-CB 4.43Å; V434-G439 WeakPolarHBondContact O-CA 3.42Å; V434-G439 PolarHBondContact O-N 3.41Å; V434-F442 HydrophobicContact CG1-CD2 4.14Å; V434-F442 HydrophobicContact CG1-CE2 4.11Å; V434-R555 WeakPolarHBondContact CB-O 3.28Å; V434-R555 WeakPolarHBondContact CG1-O 3.46Å; V434-R555 HydrophobicContact CG2-CB 4.4Å
435Q85.5Confident88.2Confident16 Ų1621.2 Ų21.28%0.07511%0.112CC..Iπ-helixtrans-53.6-47.2-177.8-73.3-179.8-45.800112.6T426 P431 S432 S558T426-Q435 PolarHBondContact O-NE2 3.24Å; P431-Q435 VanDerWaalsContact CA-OE1 3.28Å; P431-Q435 HydrophobicContact CB-CB 4.07Å; S432-Q435 WeakPolarHBondContact O-CB 3.38Å; S432-Q435 PolarHBondContact O-N 3.47Å; S432-Q435 WeakPolarHBondContact OG-CG 3.44Å; S432-Q435 PolarHBondContact OG-N 2.82Å; S432-Q435 VanDerWaalsContact OG-N 3.07Å; Q435-S558 WeakPolarHBondContact CG-O 3.33Å; Q435-S558 WeakPolarHBondContact CG-OG 3.49Å; Q435-S558 PolarHBondContact N-OG 3.39Å; Q435-S558 PolarHBondContact NE2-O 3.02Å
436H84.9Confident89.1Confident64 Ų6417.6 Ų17.630%0.2968%0.082SC..Iπ-helixtrans-116.2-9.6-172.4-71.3-177.6000115.2R232 Y233 P431 S432 V434R232-H436 VanDerWaalsContact CD-O 3.25Å; R232-H436 WeakPolarHBondContact CD-O 3.42Å; R232-H436 PolarHBondContact NE-O 3.19Å; R232-H436 PolarHBondContact NH1-O 2.97Å; Y233-H436 WeakPolarHBondContact OH-CB 3.32Å; Y233-H436 PolarHBondContact OH-ND1 3Å; Y233-H436 VanDerWaalsContact OH-ND1 3.11Å; P431-H436 HydrophobicContact CB-CB 4.21Å; P431-H436 WeakPolarHBondContact CB-ND1 3.1Å; P431-H436 HydrophobicContact CG-CB 4.41Å; P431-H436 WeakPolarHBondContact CG-ND1 3.21Å; S432-H436 PolarHBondContact O-N 3.3Å; V434-H436 VanDerWaalsContact C-N 3.3Å; V434-H436 PolarHBondContact O-N 3.06Å
437I84.3Confident89.9Confident8 Ų816.8 Ų16.84%0.0418%0.077CC..Iπ-helixtrans-116.8-68.5-177.6-51.7174000109.7T225 N228 A229 Y233 Y433T225-I437 HydrophobicContact CG2-CD1 4.03Å; N228-I437 HydrophobicContact CB-CG2 3.32Å; A229-I437 HydrophobicContact CB-CD1 3.83Å; Y233-I437 HydrophobicContact CE2-CD1 4.19Å; Y233-I437 HydrophobicContact CE2-CG1 4.22Å; Y433-I437 CarbonylContact O-C 3.49Å; Y433-I437 VanDerWaalsContact O-CA 3.24Å; Y433-I437 WeakPolarHBondContact O-CA 3.01Å; Y433-I437 WeakPolarHBondContact O-CB 3.19Å; Y433-I437 PolarHBondContact O-N 3.22Å
438M85.9Confident90.5Very high0 Ų014.3 Ų14.30%07%0.066CC..Iπ-helixtrans-81-24.9-171-59.2-59-63.500114.1Y433 V434 D440 I441 F442 Y512Y433-M438 HydrophobicContact CD2-CB 4.25Å; Y433-M438 HydrophobicContact CD2-CG 3.3Å; Y433-M438 HydrophobicContact CE2-CB 4.25Å; Y433-M438 HydrophobicContact CE2-CG 3.43Å; Y433-M438 VanDerWaalsContact CE2-CG 3.43Å; Y433-M438 HydrophobicContact CG-CG 4.44Å; Y433-M438 PolarHBondContact O-N 3Å; V434-M438 HydrophobicContact CG2-CB 4.43Å; M438-D440 VanDerWaalsContact C-N 3.29Å; M438-D440 PolarHBondContact O-N 3.02Å; M438-I441 HydrophobicContact CE-CD1 4.15Å; M438-I441 CarbonylContact O-C 3.59Å; M438-I441 WeakPolarHBondContact O-CA 3.28Å; M438-I441 WeakPolarHBondContact O-CB 3.35Å; M438-I441 PolarHBondContact O-N 3.04Å; M438-I441 VanDerWaalsContact O-N 3.07Å; M438-I441 HydrophobicContact SD-CD1 3.72Å; M438-F442 HydrophobicContact CB-CD2 4.43Å; M438-F442 HydrophobicContact CB-CE2 4.08Å; M438-F442 HydrophobicContact CB-CZ 4.49Å; M438-F442 WeakPolarHBondContact O-CD2 3.34Å; M438-F442 WeakPolarHBondContact O-CG 3.31Å; M438-F442 PolarHBondContact O-N 3Å; M438-Y512 HydrophobicContact CE-CD2 3.98Å; M438-Y512 HydrophobicContact CE-CE2 3.2Å
439G84.8Confident90.8Very high0 Ų013.4 Ų13.40%06%0.062CC..Hα-helixtrans-63.4-36.3-178.200000112.4V434 I441 F442 S443 N559V434-G439 WeakPolarHBondContact O-CA 3.42Å; V434-G439 PolarHBondContact O-N 3.41Å; G439-I441 VanDerWaalsContact C-N 3.35Å; G439-F442 PolarHBondContact O-N 3.2Å; G439-S443 WeakPolarHBondContact O-CB 3.04Å; G439-S443 PolarHBondContact O-N 2.96Å; G439-S443 PolarHBondContact O-OG 3.3Å; G439-N559 VanDerWaalsContact CA-ND2 3.29Å; G439-N559 WeakPolarHBondContact CA-ND2 3.42Å; G439-N559 PolarHBondContact O-ND2 3.24Å
440D86.4Confident91.1Very high47 Ų479.1 Ų9.125%0.2515%0.046SC..Hα-helixtrans-68.6-36.3173.2-74.4-28000111.7R232 M438 S443 L444 N640R232-D440 IonicContact NH1-OD2 3.86Å; R232-D440 PolarHBondContact NH1-OD2 3.47Å; M438-D440 VanDerWaalsContact C-N 3.29Å; M438-D440 PolarHBondContact O-N 3.02Å; D440-S443 PolarHBondContact O-N 2.85Å; D440-L444 WeakPolarHBondContact O-CG 3.43Å; D440-L444 PolarHBondContact O-N 2.87Å; D440-N640 PolarHBondContact OD1-ND2 3.34Å
441I90.2Very high91.3Very high5 Ų58.8 Ų8.83%0.0264%0.044CC..Hα-helixtrans-66.5-44.6175.9-59174.4000110.2M438 G439 S443 L444 F446 Y512M438-I441 HydrophobicContact CE-CD1 4.15Å; M438-I441 CarbonylContact O-C 3.59Å; M438-I441 WeakPolarHBondContact O-CA 3.28Å; M438-I441 WeakPolarHBondContact O-CB 3.35Å; M438-I441 PolarHBondContact O-N 3.04Å; M438-I441 VanDerWaalsContact O-N 3.07Å; M438-I441 HydrophobicContact SD-CD1 3.72Å; G439-I441 VanDerWaalsContact C-N 3.35Å; I441-S443 VanDerWaalsContact C-N 3.33Å; I441-S443 PolarHBondContact O-N 3.2Å; I441-L444 WeakPolarHBondContact O-CB 3.49Å; I441-L444 PolarHBondContact O-N 3.17Å; I441-F446 HydrophobicContact CG2-CB 3.43Å; I441-F446 VanDerWaalsContact CG2-CB 3.43Å; I441-F446 HydrophobicContact CG2-CG 4.36Å; I441-F446 PolarHBondContact O-N 2.87Å; I441-Y512 HydrophobicContact CG2-CD2 4.3Å
442F92.3Very high91.7Very high0 Ų08.2 Ų8.20%04%0.041CC..Hα-helixtrans-61.4-40.4173.4-69-39000112.4V434 M438 G439 L444 G445 F446 Y512 H545 V547V434-F442 HydrophobicContact CG1-CD2 4.14Å; V434-F442 HydrophobicContact CG1-CE2 4.11Å; M438-F442 HydrophobicContact CB-CD2 4.43Å; M438-F442 HydrophobicContact CB-CE2 4.08Å; M438-F442 HydrophobicContact CB-CZ 4.49Å; M438-F442 WeakPolarHBondContact O-CD2 3.34Å; M438-F442 WeakPolarHBondContact O-CG 3.31Å; M438-F442 PolarHBondContact O-N 3Å; G439-F442 PolarHBondContact O-N 3.2Å; F442-L444 PolarHBondContact O-N 3.18Å; F442-G445 WeakPolarHBondContact O-CA 3.22Å; F442-G445 PolarHBondContact O-N 2.94Å; F442-F446 WeakPolarHBondContact CD1-O 3.46Å; F442-Y512 HydrophobicContact CE1-CE2 4.11Å; F442-H545 AromaticContact CE2-CE1 3.5Å; F442-H545 AromaticContact CE2-NE2 3.86Å; F442-H545 AromaticContact CZ-CD2 3.76Å; F442-H545 AromaticContact CZ-CE1 3.41Å; F442-H545 VanDerWaalsContact CZ-CE1 3.41Å; F442-H545 WeakPolarHBondContact CZ-CE1 3.35Å; F442-H545 AromaticContact CZ-ND1 3.86Å; F442-H545 AromaticContact CZ-NE2 3.39Å; F442-H545 WeakPolarHBondContact CZ-NE2 3.45Å; F442-V547 HydrophobicContact CB-CB 4.23Å; F442-V547 HydrophobicContact CB-CG2 4.46Å; F442-V547 HydrophobicContact CD1-CB 4.44Å; F442-V547 WeakPolarHBondContact O-CG2 3.35Å
443S93.5Very high92.1Very high0 Ų08 Ų80%04%0.039CC..Hα-helixtrans-63.7-19175.6-66.30000113.3G439 D440 I441 G445 N638 N640 A641G439-S443 WeakPolarHBondContact O-CB 3.04Å; G439-S443 PolarHBondContact O-N 2.96Å; G439-S443 PolarHBondContact O-OG 3.3Å; D440-S443 PolarHBondContact O-N 2.85Å; I441-S443 VanDerWaalsContact C-N 3.33Å; I441-S443 PolarHBondContact O-N 3.2Å; S443-G445 VanDerWaalsContact C-N 3.28Å; S443-N638 VanDerWaalsContact CB-CG 3.46Å; S443-N638 WeakPolarHBondContact CB-OD1 3.33Å; S443-N638 PolarHBondContact OG-ND2 3.11Å; S443-N638 PolarHBondContact OG-OD1 3.32Å; S443-N640 CarbonylContact O-C 3.53Å; S443-A641 WeakPolarHBondContact O-CA 3.44Å; S443-A641 PolarHBondContact O-N 3.44Å
444L94.6Very high92.6Very high6 Ų67.5 Ų7.53%0.0314%0.037CC..THydrogen-bonded Turntrans-85.72.7169.3-61.3169.6000113.4D440 I441 F442 F446 R482 V483 Q486 N640D440-L444 WeakPolarHBondContact O-CG 3.43Å; D440-L444 PolarHBondContact O-N 2.87Å; I441-L444 WeakPolarHBondContact O-CB 3.49Å; I441-L444 PolarHBondContact O-N 3.17Å; F442-L444 PolarHBondContact O-N 3.18Å; L444-F446 VanDerWaalsContact C-N 3.25Å; L444-F446 HydrophobicContact CB-CD2 3.77Å; L444-F446 HydrophobicContact CB-CE2 4.3Å; L444-F446 PolarHBondContact O-N 2.92Å; L444-R482 HydrophobicContact CD1-CG 4.08Å; L444-R482 VanDerWaalsContact CD2-NH2 3.3Å; L444-V483 HydrophobicContact CD2-CG2 4.49Å; L444-Q486 HydrophobicContact CD1-CG 4.42Å; L444-N640 HydrophobicContact CD2-CB 3.82Å; L444-N640 HydrophobicContact CG-CB 4.19Å
445G96.1Very high93.2Very high1 Ų18.4 Ų8.41%0.014%0.043CC..THydrogen-bonded Turntrans81.3-4.6-174.900000114.4F442 S443 D514F442-G445 WeakPolarHBondContact O-CA 3.22Å; F442-G445 PolarHBondContact O-N 2.94Å; S443-G445 VanDerWaalsContact C-N 3.28Å; G445-D514 WeakPolarHBondContact O-CA 3.16Å
446F96.9Very high93.7Very high0 Ų09.4 Ų9.40%06%0.058CC..  trans-72.5131.2179.3-78.7-99.3000110.7I441 F442 L444 V483 Q486 Y487 D514I441-F446 HydrophobicContact CG2-CB 3.43Å; I441-F446 VanDerWaalsContact CG2-CB 3.43Å; I441-F446 HydrophobicContact CG2-CG 4.36Å; I441-F446 PolarHBondContact O-N 2.87Å; F442-F446 WeakPolarHBondContact CD1-O 3.46Å; L444-F446 VanDerWaalsContact C-N 3.25Å; L444-F446 HydrophobicContact CB-CD2 3.77Å; L444-F446 HydrophobicContact CB-CE2 4.3Å; L444-F446 PolarHBondContact O-N 2.92Å; F446-V483 HydrophobicContact CE2-CG1 3.9Å; F446-V483 HydrophobicContact CZ-CG1 3.9Å; F446-Q486 HydrophobicContact CD1-CB 3.8Å; F446-Q486 HydrophobicContact CD2-CB 4.2Å; F446-Q486 HydrophobicContact CD2-CG 4.37Å; F446-Q486 HydrophobicContact CE1-CB 3.55Å; F446-Q486 HydrophobicContact CE2-CB 3.98Å; F446-Q486 HydrophobicContact CE2-CG 4.38Å; F446-Q486 HydrophobicContact CG-CB 4.11Å; F446-Q486 HydrophobicContact CZ-CB 3.65Å; F446-Y487 AromaticContact CE1-CD1 3.92Å; F446-Y487 HydrophobicContact CE1-CD1 3.92Å; F446-Y487 HydrophobicContact CE1-CD2 4.4Å; F446-Y487 AromaticContact CE1-CE1 3.83Å; F446-Y487 HydrophobicContact CE1-CE1 3.83Å; F446-Y487 HydrophobicContact CE1-CE2 4.31Å; F446-Y487 HydrophobicContact CE1-CG 4.22Å; F446-Y487 HydrophobicContact CZ-CD1 4.2Å; F446-Y487 AromaticContact CZ-CD2 3.89Å; F446-Y487 HydrophobicContact CZ-CD2 3.89Å; F446-Y487 AromaticContact CZ-CE1 3.98Å; F446-Y487 HydrophobicContact CZ-CE1 3.98Å; F446-Y487 AromaticContact CZ-CE2 3.65Å; F446-Y487 HydrophobicContact CZ-CE2 3.65Å; F446-Y487 HydrophobicContact CZ-CG 4.17Å; F446-Y487 AromaticContact CZ-CZ 3.71Å; F446-D514 HydrophobicContact CD2-CB 3.82Å; F446-D514 HydrophobicContact CE2-CB 3.75Å; F446-D514 HydrophobicContact CG-CB 4.26Å; F446-D514 HydrophobicContact CZ-CB 4.14Å
447G95.9Very high94.4Very high0 Ų09.8 Ų9.80%06%0.062CC..EExtended strand (participates in β ladder)trans-170.6-178.1175.900000111.2F449 Y512 S513 R518 D546G447-F449 PolarHBondContact O-N 3.18Å; G447-Y512 VanDerWaalsContact CA-CD2 3.5Å; G447-Y512 WeakPolarHBondContact O-CA 3.22Å; G447-S513 PolarHBondContact N-O 3.47Å; G447-S513 PolarHBondContact O-N 3.49Å; G447-S513 VanDerWaalsContact O-N 3.09Å; G447-R518 PolarHBondContact O-NH2 2.7Å; G447-D546 WeakPolarHBondContact CA-OD1 3.3Å
448P96.1Very high95Very high2 Ų213.1 Ų13.11%0.0139%0.085CC..EExtended strand (participates in β ladder)trans-59.4126.1-171.424.2-34000111.3I510 Y512 R542 D543 H545 D546P448-I510 HydrophobicContact CB-CD1 4.1Å; P448-Y512 HydrophobicContact CB-CD1 4.29Å; P448-Y512 HydrophobicContact CB-CE1 3.8Å; P448-Y512 HydrophobicContact CG-CE1 4.34Å; P448-R542 HydrophobicContact CB-CB 4.27Å; P448-R542 HydrophobicContact CG-CB 4.18Å; P448-R542 WeakPolarHBondContact O-CB 3.22Å; P448-D543 HydrophobicContact CB-CB 4.28Å; P448-D543 HydrophobicContact CG-CB 4.08Å; P448-H545 WeakPolarHBondContact CD-O 3.29Å; P448-H545 WeakPolarHBondContact CG-O 3.39Å; P448-D546 HydrophobicContact CG-CB 4.04Å
449F97.9Very high95.6Very high1 Ų118.8 Ų18.80%0.00411%0.111CC..EExtended strand (participates in β ladder)trans-124.8115.5168.8-176.4-100.6000107.7G447 W451 I510 L511 R518 I521 A522 I540 L622G447-F449 PolarHBondContact O-N 3.18Å; F449-W451 HydrophobicContact CD1-CE3 4.07Å; F449-W451 HydrophobicContact CD1-CZ3 4.21Å; F449-W451 HydrophobicContact CE1-CE3 4.07Å; F449-W451 HydrophobicContact CE1-CZ3 4.42Å; F449-I510 CarbonylContact O-C 3.59Å; F449-I510 WeakPolarHBondContact O-CA 3.45Å; F449-L511 HydrophobicContact CB-CD1 4.22Å; F449-L511 HydrophobicContact CD1-CD1 4.39Å; F449-L511 PolarHBondContact N-O 3.23Å; F449-L511 PolarHBondContact O-N 3.12Å; F449-L511 VanDerWaalsContact O-O 3.14Å; F449-R518 HydrophobicContact CB-CG 4.09Å; F449-R518 HydrophobicContact CD2-CB 3.82Å; F449-R518 HydrophobicContact CD2-CG 3.5Å; F449-R518 VanDerWaalsContact CD2-CG 3.5Å; F449-R518 HydrophobicContact CE2-CB 3.91Å; F449-R518 HydrophobicContact CE2-CG 4.13Å; F449-R518 HydrophobicContact CG-CG 3.98Å; F449-I521 HydrophobicContact CD1-CD1 4.45Å; F449-I521 HydrophobicContact CD1-CG2 4.44Å; F449-I521 HydrophobicContact CE1-CB 3.95Å; F449-I521 HydrophobicContact CE1-CD1 4.45Å; F449-I521 HydrophobicContact CE1-CG2 3.54Å; F449-I521 HydrophobicContact CZ-CB 4.29Å; F449-I521 HydrophobicContact CZ-CG2 4.16Å; F449-A522 HydrophobicContact CZ-CB 4.25Å; F449-I540 HydrophobicContact CD2-CG2 4.05Å; F449-I540 HydrophobicContact CE1-CD1 4.29Å; F449-I540 HydrophobicContact CE2-CG2 3.35Å; F449-I540 HydrophobicContact CZ-CD1 3.87Å; F449-I540 HydrophobicContact CZ-CG1 4.31Å; F449-I540 HydrophobicContact CZ-CG2 3.68Å; F449-L622 HydrophobicContact CE2-CD1 4.29Å; F449-L622 HydrophobicContact CE2-CD2 4.43Å
450R97.6Very high96.3Very high6 Ų619.1 Ų19.12%0.02311%0.113CC..EExtended strand (participates in β ladder)trans-122.9154.9-175.196.6-161.2-62.7162.46.4110.7T206 C211 I213 R509 I510 I540 S541T206-R450 VanDerWaalsContact CG2-NH1 3.28Å; C211-R450 PolarHBondContact O-NE 3.44Å; C211-R450 VanDerWaalsContact O-NE 3.15Å; C211-R450 PolarHBondContact O-NH1 2.8Å; C211-R450 PolarHBondContact O-NH2 2.57Å; I213-R450 HydrophobicContact CD1-CB 4.33Å; I213-R450 VanDerWaalsContact N-NH2 3.13Å; R450-R509 CarbonylContact C-O 3.6Å; R450-R509 VanDerWaalsContact CA-O 3.23Å; R450-R509 WeakPolarHBondContact CA-O 3.25Å; R450-R509 WeakPolarHBondContact CB-O 3.41Å; R450-I510 HydrophobicContact CB-CB 4.17Å; R450-I510 HydrophobicContact CB-CG1 4.17Å; R450-I540 WeakPolarHBondContact O-CA 3.47Å; R450-S541 VanDerWaalsContact CG-C 3.46Å; R450-S541 WeakPolarHBondContact CG-O 3.44Å; R450-S541 PolarHBondContact N-O 2.83Å; R450-S541 PolarHBondContact O-N 3.19Å; R450-S541 VanDerWaalsContact O-O 3.14Å
451W98.8Very high96.8Very high0 Ų017.1 Ų17.10%010%0.102CC..EExtended strand (participates in β ladder)trans-144.9159.6170.168.692.5000113.2F449 T464 A468 I494 A508 R509 L511 I525 V538 V539 I540F449-W451 HydrophobicContact CD1-CE3 4.07Å; F449-W451 HydrophobicContact CD1-CZ3 4.21Å; F449-W451 HydrophobicContact CE1-CE3 4.07Å; F449-W451 HydrophobicContact CE1-CZ3 4.42Å; W451-T464 VanDerWaalsContact NE1-CB 3.28Å; W451-T464 PolarHBondContact NE1-OG1 3.17Å; W451-A468 HydrophobicContact CH2-CB 3.75Å; W451-A468 HydrophobicContact CZ2-CB 4.37Å; W451-A468 HydrophobicContact CZ3-CB 4.45Å; W451-I494 HydrophobicContact CH2-CD1 3.84Å; W451-I494 HydrophobicContact CZ2-CD1 4.33Å; W451-A508 CarbonylContact O-C 3.57Å; W451-A508 WeakPolarHBondContact O-CA 3.26Å; W451-A508 WeakPolarHBondContact O-CB 3.47Å; W451-R509 HydrophobicContact CD2-CB 4.03Å; W451-R509 HydrophobicContact CE3-CB 4.34Å; W451-R509 HydrophobicContact CH2-CB 3.8Å; W451-R509 HydrophobicContact CH2-CG 3.43Å; W451-R509 VanDerWaalsContact CH2-CG 3.43Å; W451-R509 HydrophobicContact CZ2-CB 3.42Å; W451-R509 VanDerWaalsContact CZ2-CB 3.42Å; W451-R509 HydrophobicContact CZ2-CG 3.47Å; W451-R509 VanDerWaalsContact CZ2-CG 3.47Å; W451-R509 HydrophobicContact CZ3-CB 4.23Å; W451-R509 HydrophobicContact CZ3-CG 4.05Å; W451-R509 PolarHBondContact N-O 2.84Å; W451-R509 PolarHBondContact O-N 2.75Å; W451-L511 HydrophobicContact CH2-CD2 3.96Å; W451-L511 HydrophobicContact CZ3-CD2 3.9Å; W451-L511 HydrophobicContact CZ3-CG 4.07Å; W451-I525 HydrophobicContact CD2-CD1 4.36Å; W451-I525 HydrophobicContact CG-CD1 4.38Å; W451-V538 HydrophobicContact CB-CG1 3.74Å; W451-V538 HydrophobicContact CG-CG1 4.18Å; W451-V539 CarbonylContact C-O 3.56Å; W451-V539 WeakPolarHBondContact CA-O 3.3Å; W451-V539 WeakPolarHBondContact CB-O 3.46Å; W451-I540 HydrophobicContact CB-CD1 3.49Å; W451-I540 VanDerWaalsContact CB-CD1 3.49Å; W451-I540 HydrophobicContact CG-CD1 4.49Å
452V98.9Very high97.2Very high1 Ų118.8 Ų18.81%0.00612%0.117CC..EExtended strand (participates in β ladder)trans-132121.8177.5-178.30000109.4L105 M106 I213 T454 Q507 A508 V538 V539L105-V452 HydrophobicContact CD2-CG1 4.25Å; M106-V452 HydrophobicContact CE-CG2 3.77Å; M106-V452 HydrophobicContact SD-CB 3.89Å; M106-V452 HydrophobicContact SD-CG1 3.96Å; M106-V452 HydrophobicContact SD-CG2 3.74Å; I213-V452 HydrophobicContact CG2-CG2 3.88Å; V452-T454 PolarHBondContact O-N 3.28Å; V452-Q507 CarbonylContact C-O 3.54Å; V452-Q507 WeakPolarHBondContact CA-O 3.38Å; V452-A508 HydrophobicContact CG2-CB 3.83Å; V452-V538 WeakPolarHBondContact O-CA 3.37Å; V452-V539 HydrophobicContact CB-CB 4.38Å; V452-V539 PolarHBondContact N-O 2.93Å; V452-V539 PolarHBondContact O-N 2.82Å
453C98.8Very high97.5Very high1 Ų120.3 Ų20.31%0.00713%0.126CC..EExtended strand (participates in β ladder)trans-76.4111.9173.6-59.30000108.9S455 G456 D460 Q507C453-S455 PolarHBondContact O-N 3.42Å; C453-G456 PolarHBondContact O-N 3.37Å; C453-D460 HydrophobicContact CB-CB 3.94Å; C453-Q507 HydrophobicContact CB-CB 4.16Å; C453-Q507 PolarHBondContact N-O 2.73Å
454T98.8Very high97.8Very high0 Ų020.3 Ų20.30%013%0.126CC..THydrogen-bonded Turntrans-77.5-6.4-170.671.70000113.9P89 I90 L105 V452 G456 P537 V539 L607P89-T454 CarbonylContact C-O 3.32Å; P89-T454 WeakPolarHBondContact CA-O 3.38Å; I90-T454 HydrophobicContact CD1-CG2 4.24Å; I90-T454 WeakPolarHBondContact CG2-OG1 3.03Å; I90-T454 PolarHBondContact N-O 2.86Å; L105-T454 HydrophobicContact CD1-CG2 4.26Å; V452-T454 PolarHBondContact O-N 3.28Å; T454-G456 VanDerWaalsContact C-N 3.29Å; T454-P537 VanDerWaalsContact CB-O 3.26Å; T454-P537 WeakPolarHBondContact CB-O 3.17Å; T454-P537 VanDerWaalsContact CG2-O 3.24Å; T454-P537 WeakPolarHBondContact CG2-O 3.26Å; T454-P537 PolarHBondContact N-O 2.75Å; T454-P537 VanDerWaalsContact N-O 3.11Å; T454-P537 PolarHBondContact OG1-O 3.34Å; T454-V539 HydrophobicContact CG2-CG2 3.79Å; T454-L607 HydrophobicContact CG2-CD1 4.45Å
455S98.4Very high98Very high18 Ų1820.7 Ų20.713%0.12613%0.128CC..THydrogen-bonded Turntrans-67.8-28.6168.554.80000112.7P89 C453 D457 D460 S535P89-S455 WeakPolarHBondContact CB-O 3.27Å; P89-S455 WeakPolarHBondContact CG-O 3.21Å; C453-S455 PolarHBondContact O-N 3.42Å; S455-D457 PolarHBondContact O-N 2.85Å; S455-D457 PolarHBondContact OG-N 2.87Å; S455-D460 WeakPolarHBondContact CB-OD2 3.5Å; S455-D460 PolarHBondContact OG-OD2 3.4Å; S455-S535 WeakPolarHBondContact CB-OG 3.25Å
456G97.6Very high98.1Very high38 Ų3825.2 Ų25.239%0.39215%0.152SC..  trans72.58.4-167.600000114.2C453 T454 Q507C453-G456 PolarHBondContact O-N 3.37Å; T454-G456 VanDerWaalsContact C-N 3.29Å; G456-Q507 WeakPolarHBondContact O-CG 3.47Å
457D97.9Very high98.2Very high71 Ų7126.1 Ų26.138%0.3816%0.157SC..  trans-85.4121.9179.1-168.6-18.1000111.4S455 Q459 D460 L461S455-D457 PolarHBondContact O-N 2.85Å; S455-D457 PolarHBondContact OG-N 2.87Å; D457-Q459 PolarHBondContact O-N 3.49Å; D457-Q459 WeakPolarHBondContact OD1-CB 3.28Å; D457-Q459 PolarHBondContact OD1-N 2.91Å; D457-D460 PolarHBondContact O-N 3.36Å; D457-L461 PolarHBondContact O-N 3.34Å
458P97.9Very high98.3Very high79 Ų7926.1 Ų26.151%0.51316%0.157SC..Hα-helixtrans-56.2-26.2172.3-23.232.4000114.4L461 A462P458-L461 WeakPolarHBondContact O-CB 2.96Å; P458-L461 PolarHBondContact O-N 3.47Å; P458-A462 PolarHBondContact O-N 3.48Å
459Q98.3Very high98.4Very high119 Ų11926.2 Ų26.256%0.55616%0.158SC*.Hα-helixtrans-69-39.9178.7-174.658.228.500111.7D457 L461 A462 V463D457-Q459 PolarHBondContact O-N 3.49Å; D457-Q459 WeakPolarHBondContact OD1-CB 3.28Å; D457-Q459 PolarHBondContact OD1-N 2.91Å; Q459-L461 PolarHBondContact O-N 2.99Å; Q459-A462 PolarHBondContact O-N 3.11Å; Q459-V463 WeakPolarHBondContact O-CG2 3.19Å; Q459-V463 PolarHBondContact O-N 3.23Å
460D98.7Very high98.5Very high6 Ų632.2 Ų32.23%0.03218%0.184CC..Hα-helixtrans-59.9-40.2172.9-81.3-11.6000110.6C453 S455 D457 V463 T464 V534 S535C453-D460 HydrophobicContact CB-CB 3.94Å; S455-D460 WeakPolarHBondContact CB-OD2 3.5Å; S455-D460 PolarHBondContact OG-OD2 3.4Å; D457-D460 PolarHBondContact O-N 3.36Å; D460-V463 PolarHBondContact O-N 3.22Å; D460-T464 WeakPolarHBondContact O-CG2 3.46Å; D460-T464 PolarHBondContact O-N 3.15Å; D460-T464 PolarHBondContact O-OG1 3.44Å; D460-V534 HydrophobicContact CB-CG1 4.07Å; D460-V534 WeakPolarHBondContact OD1-CA 3.22Å; D460-S535 PolarHBondContact OD1-N 2.81Å; D460-S535 PolarHBondContact OD1-OG 3.18Å; D460-S535 PolarHBondContact OD2-N 2.69Å; D460-S535 PolarHBondContact OD2-OG 2.84Å
461L98.6Very high98.5Very high6 Ų632.7 Ų32.73%0.03119%0.187CC..Hα-helixtrans-62.7-45.5176.7-170.162.4000111.5D457 P458 Q459 V463 T464 D465 V503 Q507 R509D457-L461 PolarHBondContact O-N 3.34Å; P458-L461 WeakPolarHBondContact O-CB 2.96Å; P458-L461 PolarHBondContact O-N 3.47Å; Q459-L461 PolarHBondContact O-N 2.99Å; L461-V463 VanDerWaalsContact C-N 3.34Å; L461-V463 PolarHBondContact O-N 2.97Å; L461-T464 WeakPolarHBondContact CA-OG1 3.45Å; L461-T464 PolarHBondContact O-N 2.6Å; L461-T464 PolarHBondContact O-OG1 3.01Å; L461-D465 PolarHBondContact O-N 2.73Å; L461-V503 HydrophobicContact CD2-CG2 3.69Å; L461-Q507 HydrophobicContact CB-CB 4.29Å; L461-Q507 HydrophobicContact CD2-CB 4.35Å; L461-R509 HydrophobicContact CD1-CB 3.9Å
462A98.4Very high98.5Very high39 Ų3932.7 Ų32.732%0.32219%0.187SC..Hα-helixtrans-60.1-42.5176.400000112.1P458 Q459 T464 D465 D466P458-A462 PolarHBondContact O-N 3.48Å; Q459-A462 PolarHBondContact O-N 3.11Å; A462-T464 PolarHBondContact O-N 3.32Å; A462-D465 PolarHBondContact O-N 3.46Å; A462-D466 PolarHBondContact O-N 3.18Å
463V98.8Very high98.4Very high32 Ų3236 Ų3619%0.19420%0.203CC..Hα-helixtrans-62.3-43.5175.4172.70000111Q459 D460 L461 D466 I467 V534Q459-V463 WeakPolarHBondContact O-CG2 3.19Å; Q459-V463 PolarHBondContact O-N 3.23Å; D460-V463 PolarHBondContact O-N 3.22Å; L461-V463 VanDerWaalsContact C-N 3.34Å; L461-V463 PolarHBondContact O-N 2.97Å; V463-D466 PolarHBondContact O-N 3.45Å; V463-I467 HydrophobicContact CG1-CD1 3.89Å; V463-I467 VanDerWaalsContact O-CG1 3.28Å; V463-I467 WeakPolarHBondContact O-CG1 3.37Å; V463-I467 PolarHBondContact O-N 2.93Å; V463-V534 HydrophobicContact CB-CG2 4.38Å; V463-V534 HydrophobicContact CG1-CG2 3.83Å
464T98.7Very high98.4Very high0 Ų042.5 Ų42.50%023%0.233CC..Hα-helixtrans-68.5-34.2177.356.20000113.4W451 D460 L461 A462 I467 A468 I525 V534W451-T464 VanDerWaalsContact NE1-CB 3.28Å; W451-T464 PolarHBondContact NE1-OG1 3.17Å; D460-T464 WeakPolarHBondContact O-CG2 3.46Å; D460-T464 PolarHBondContact O-N 3.15Å; D460-T464 PolarHBondContact O-OG1 3.44Å; L461-T464 WeakPolarHBondContact CA-OG1 3.45Å; L461-T464 PolarHBondContact O-N 2.6Å; L461-T464 PolarHBondContact O-OG1 3.01Å; A462-T464 PolarHBondContact O-N 3.32Å; T464-I467 PolarHBondContact O-N 2.98Å; T464-A468 WeakPolarHBondContact O-CB 3.43Å; T464-A468 PolarHBondContact O-N 3.5Å; T464-I525 HydrophobicContact CG2-CD1 4.31Å; T464-I525 HydrophobicContact CG2-CG1 4.26Å; T464-I525 HydrophobicContact CG2-CG2 4.43Å; T464-V534 HydrophobicContact CG2-CG2 3.94Å
465D98.6Very high98.2Very high14 Ų1443.3 Ų43.38%0.07524%0.237CC..Hα-helixtrans-60.9-45.6172.6-75.5-10.3000110.3L461 A462 A468 A469 I494 R509L461-D465 PolarHBondContact O-N 2.73Å; A462-D465 PolarHBondContact O-N 3.46Å; D465-A468 PolarHBondContact O-N 2.98Å; D465-A469 WeakPolarHBondContact O-CB 3.3Å; D465-A469 PolarHBondContact O-N 3.16Å; D465-I494 HydrophobicContact CB-CD1 4.14Å; D465-I494 HydrophobicContact CB-CG1 4.27Å; D465-I494 WeakPolarHBondContact OD1-CD1 3.4Å; D465-R509 VanDerWaalsContact OD1-CG 3.24Å; D465-R509 WeakPolarHBondContact OD1-CG 3.46Å; D465-R509 IonicContact OD1-CZ 2.94Å; D465-R509 IonicContact OD1-NE 3.85Å; D465-R509 PolarHBondContact OD1-NE 3Å; D465-R509 IonicContact OD1-NH2 2.62Å; D465-R509 IonicContact OD2-CZ 3.53Å; D465-R509 IonicContact OD2-NE 2.76Å; D465-R509 PolarHBondContact OD2-NE 3.07Å; D465-R509 VanDerWaalsContact OD2-NE 3.16Å; D465-R509 IonicContact OD2-NH2 3.07Å; D465-R509 PolarHBondContact OD2-NH2 3.06Å
466D98.6Very high98.1Very high97 Ų9743 Ų4352%0.51924%0.235SC..Hα-helixtrans-65.4-40.4177.4-79.8-14.6000112.6A462 V463 A469 K470A462-D466 PolarHBondContact O-N 3.18Å; V463-D466 PolarHBondContact O-N 3.45Å; D466-A469 PolarHBondContact O-N 2.93Å; D466-K470 WeakPolarHBondContact O-CG 3.47Å; D466-K470 PolarHBondContact O-N 3.5Å; D466-K470 VanDerWaalsContact O-N 3.09Å
467I98.8Very high98Very high19 Ų1944.3 Ų44.310%0.09724%0.242CC..Hα-helixtrans-60.5-50174.6-72.3164.8000109.9V463 T464 A469 K470 V471 A524 I525 A528V463-I467 HydrophobicContact CG1-CD1 3.89Å; V463-I467 VanDerWaalsContact O-CG1 3.28Å; V463-I467 WeakPolarHBondContact O-CG1 3.37Å; V463-I467 PolarHBondContact O-N 2.93Å; T464-I467 PolarHBondContact O-N 2.98Å; I467-A469 PolarHBondContact O-N 3.48Å; I467-K470 PolarHBondContact O-N 2.89Å; I467-V471 HydrophobicContact CG2-CG2 4.44Å; I467-V471 WeakPolarHBondContact O-CG2 3.31Å; I467-V471 PolarHBondContact O-N 3.17Å; I467-A524 HydrophobicContact CG2-CB 3.55Å; I467-I525 HydrophobicContact CG2-CG1 4.2Å; I467-A528 HydrophobicContact CD1-CB 3.5Å
468A98.7Very high97.6Very high0 Ų047.9 Ų47.90%026%0.262CS..Hα-helixtrans-60.3-46.3-18000000111.2W451 T464 D465 K470 V471 L472 I494 L511 I521W451-A468 HydrophobicContact CH2-CB 3.75Å; W451-A468 HydrophobicContact CZ2-CB 4.37Å; W451-A468 HydrophobicContact CZ3-CB 4.45Å; T464-A468 WeakPolarHBondContact O-CB 3.43Å; T464-A468 PolarHBondContact O-N 3.5Å; D465-A468 PolarHBondContact O-N 2.98Å; A468-K470 PolarHBondContact O-N 3.31Å; A468-V471 PolarHBondContact O-N 3.33Å; A468-L472 VanDerWaalsContact O-CG 3.27Å; A468-L472 WeakPolarHBondContact O-CG 3.24Å; A468-L472 PolarHBondContact O-N 3.22Å; A468-I494 HydrophobicContact CB-CG1 4.28Å; A468-L511 HydrophobicContact CB-CD2 3.97Å; A468-I521 HydrophobicContact CB-CD1 4.39Å; A468-I521 HydrophobicContact CB-CG2 4.28Å
469A98.4Very high97.4Very high4 Ų445.6 Ų45.63%0.03325%0.246CC..Hα-helixtrans-55.9-48.9177.500000112.5D465 D466 I467 L472 E473 I494 R495D465-A469 WeakPolarHBondContact O-CB 3.3Å; D465-A469 PolarHBondContact O-N 3.16Å; D466-A469 PolarHBondContact O-N 2.93Å; I467-A469 PolarHBondContact O-N 3.48Å; A469-L472 PolarHBondContact O-N 3.09Å; A469-E473 VanDerWaalsContact O-CG 3.31Å; A469-E473 WeakPolarHBondContact O-CG 3.33Å; A469-E473 PolarHBondContact O-N 2.57Å; A469-I494 HydrophobicContact CB-CG2 3.79Å; A469-R495 HydrophobicContact CB-CG 4.48Å
470K98.4Very high97.1Very high127 Ų12742.2 Ų42.255%0.55224%0.236SC*.Hα-helixtrans-62.1-47.2179.8-72.3172-177.3174.50112.2D466 I467 A468 L472 E473 E474D466-K470 WeakPolarHBondContact O-CG 3.47Å; D466-K470 PolarHBondContact O-N 3.5Å; D466-K470 VanDerWaalsContact O-N 3.09Å; I467-K470 PolarHBondContact O-N 2.89Å; A468-K470 PolarHBondContact O-N 3.31Å; K470-L472 VanDerWaalsContact C-N 3.31Å; K470-L472 PolarHBondContact O-N 2.99Å; K470-E473 PolarHBondContact O-N 3.01Å; K470-E474 WeakPolarHBondContact O-CG 3.46Å; K470-E474 PolarHBondContact O-N 2.82Å
471V98.5Very high96.7Very high16 Ų1646.3 Ų46.310%0.09725%0.254CS..Hα-helixtrans-59.6-44.2178.6170.30000110.9I467 A468 E474 I475 C520 I521 A524I467-V471 HydrophobicContact CG2-CG2 4.44Å; I467-V471 WeakPolarHBondContact O-CG2 3.31Å; I467-V471 PolarHBondContact O-N 3.17Å; A468-V471 PolarHBondContact O-N 3.33Å; V471-E474 PolarHBondContact O-N 2.94Å; V471-I475 HydrophobicContact CG1-CD1 3.81Å; V471-I475 VanDerWaalsContact O-CG1 3.3Å; V471-I475 WeakPolarHBondContact O-CG1 3.39Å; V471-I475 PolarHBondContact O-N 3.07Å; V471-I475 VanDerWaalsContact O-N 3.11Å; V471-C520 HydrophobicContact CG1-CB 3.51Å; V471-I521 HydrophobicContact CB-CG1 4.02Å; V471-I521 HydrophobicContact CG1-CG1 3.7Å; V471-A524 HydrophobicContact CG2-CB 3.98Å
472L98.3Very high96.1Very high0 Ų050.2 Ų50.20%027%0.269CS..Hα-helixtrans-65.5-38.8178.7-66.7-169000112.2A468 A469 K470 I475 A476 Y487 N490 I491 L511 I521A468-L472 VanDerWaalsContact O-CG 3.27Å; A468-L472 WeakPolarHBondContact O-CG 3.24Å; A468-L472 PolarHBondContact O-N 3.22Å; A469-L472 PolarHBondContact O-N 3.09Å; K470-L472 VanDerWaalsContact C-N 3.31Å; K470-L472 PolarHBondContact O-N 2.99Å; L472-I475 PolarHBondContact O-N 3.2Å; L472-A476 WeakPolarHBondContact O-CB 3.08Å; L472-A476 PolarHBondContact O-N 3.24Å; L472-Y487 HydrophobicContact CB-CD1 4.36Å; L472-Y487 HydrophobicContact CD2-CD1 3.68Å; L472-Y487 HydrophobicContact CD2-CE1 3.56Å; L472-Y487 HydrophobicContact CG-CD1 4.42Å; L472-N490 HydrophobicContact CD1-CB 4.07Å; L472-I491 HydrophobicContact CB-CD1 4.03Å; L472-I491 HydrophobicContact CB-CG1 3.59Å; L472-I491 HydrophobicContact CD1-CG1 4.24Å; L472-L511 HydrophobicContact CD1-CD1 4.4Å; L472-L511 HydrophobicContact CD1-CD2 4.05Å; L472-I521 HydrophobicContact CD2-CD1 3.78Å; L472-I521 HydrophobicContact CG-CD1 4.22Å
473E97.9Very high95.9Very high71 Ų7148.7 Ų48.733%0.33226%0.256SS..Hα-helixtrans-64.3-42.7177.4-76.9170.4175.900112.6A469 K470 A476 A477 I491 R495A469-E473 VanDerWaalsContact O-CG 3.31Å; A469-E473 WeakPolarHBondContact O-CG 3.33Å; A469-E473 PolarHBondContact O-N 2.57Å; K470-E473 PolarHBondContact O-N 3.01Å; E473-A476 PolarHBondContact O-N 2.88Å; E473-A477 PolarHBondContact O-N 3.05Å; E473-I491 HydrophobicContact CG-CD1 3.81Å; E473-I491 HydrophobicContact CG-CG1 4.2Å; E473-I491 HydrophobicContact CG-CG2 4.09Å; E473-I491 WeakPolarHBondContact OE1-CG2 3.36Å; E473-R495 IonicContact OE1-CZ 3.53Å; E473-R495 IonicContact OE1-NE 2.8Å; E473-R495 PolarHBondContact OE1-NE 3.32Å; E473-R495 IonicContact OE1-NH2 3.2Å; E473-R495 PolarHBondContact OE1-NH2 2.9Å; E473-R495 IonicContact OE2-NH2 3.44Å; E473-R495 PolarHBondContact OE2-NH2 2.87Å
474E97.4Very high95.7Very high137 Ų13750.5 Ų50.564%0.6426%0.259SS*.Hα-helixtrans-63-43.2176.1-72172.7-171.400111.8K470 V471K470-E474 WeakPolarHBondContact O-CG 3.46Å; K470-E474 PolarHBondContact O-N 2.82Å; V471-E474 PolarHBondContact O-N 2.94Å
475I96.1Very high95.4Very high17 Ų1752.4 Ų52.49%0.08727%0.268CS..Hα-helixtrans-69-43.4178.5-64.5168.3000110.9V471 L472 A477 N478 V479 Y487 K516 C520V471-I475 HydrophobicContact CG1-CD1 3.81Å; V471-I475 VanDerWaalsContact O-CG1 3.3Å; V471-I475 WeakPolarHBondContact O-CG1 3.39Å; V471-I475 PolarHBondContact O-N 3.07Å; V471-I475 VanDerWaalsContact O-N 3.11Å; L472-I475 PolarHBondContact O-N 3.2Å; I475-A477 PolarHBondContact O-N 3.21Å; I475-A477 VanDerWaalsContact O-N 3.08Å; I475-N478 PolarHBondContact O-N 3.2Å; I475-N478 VanDerWaalsContact O-N 3.1Å; I475-V479 HydrophobicContact CG2-CG1 4.12Å; I475-Y487 HydrophobicContact CG2-CD2 4.4Å; I475-Y487 HydrophobicContact CG2-CE1 4.4Å; I475-Y487 HydrophobicContact CG2-CE2 3.59Å; I475-Y487 WeakPolarHBondContact CG2-OH 3.17Å; I475-K516 HydrophobicContact CD1-CG 4.37Å; I475-C520 HydrophobicContact CD1-CB 4.07Å
476A96.3Very high95.2Very high11 Ų1152.3 Ų52.39%0.09127%0.267CS..Hα-helixtrans-59.3-24.5-176.700000113.7L472 E473 N478 R484 Y487 I491L472-A476 WeakPolarHBondContact O-CB 3.08Å; L472-A476 PolarHBondContact O-N 3.24Å; E473-A476 PolarHBondContact O-N 2.88Å; A476-N478 VanDerWaalsContact C-N 3.3Å; A476-N478 PolarHBondContact O-N 3.04Å; A476-R484 HydrophobicContact CB-CG 4.49Å; A476-R484 PolarHBondContact O-NE 2.85Å; A476-Y487 HydrophobicContact CB-CD2 4.43Å; A476-Y487 HydrophobicContact CB-CG 4.32Å; A476-I491 HydrophobicContact CB-CD1 4.2Å
477A94.1Very high95Very high65 Ų6547.7 Ų47.754%0.53724%0.242SC..THydrogen-bonded Turntrans-64.9-30.5177.900000113.4E473 I475E473-A477 PolarHBondContact O-N 3.05Å; I475-A477 PolarHBondContact O-N 3.21Å; I475-A477 VanDerWaalsContact O-N 3.08Å
478N91.1Very high94.9Very high147 Ų14752.3 Ų52.379%0.78626%0.258SS*.THydrogen-bonded Turntrans-119.828.9-167.2-63.8-54.1000113.8I475 A476I475-N478 PolarHBondContact O-N 3.2Å; I475-N478 VanDerWaalsContact O-N 3.1Å; A476-N478 VanDerWaalsContact C-N 3.3Å; A476-N478 PolarHBondContact O-N 3.04Å
479V93.3Very high94.5Very high31 Ų3152.8 Ų52.819%0.18826%0.261CS..SBendtrans-125164.9-179.2-64.50000111.9I475 V483 R484 Y487I475-V479 HydrophobicContact CG2-CG1 4.12Å; V479-V483 HydrophobicContact CB-CB 4.09Å; V479-V483 HydrophobicContact CB-CG1 3.77Å; V479-V483 HydrophobicContact CG1-CG1 4.08Å; V479-V483 HydrophobicContact CG2-CB 4.17Å; V479-V483 HydrophobicContact CG2-CG1 3.81Å; V479-R484 HydrophobicContact CG2-CB 4.01Å; V479-R484 PolarHBondContact O-NH2 3.34Å; V479-Y487 HydrophobicContact CG1-CE2 4.46Å; V479-Y487 HydrophobicContact CG2-CD2 4.13Å; V479-Y487 HydrophobicContact CG2-CE2 4.38Å
480S90.6Very high94.4Very high48 Ų4852.6 Ų52.634%0.33626%0.259SS..  trans-62.8156.5176.167.90000111.8R482 V483 R484S480-R482 VanDerWaalsContact C-N 3.26Å; S480-R482 PolarHBondContact O-N 2.86Å; S480-V483 PolarHBondContact O-N 3.28Å; S480-V483 VanDerWaalsContact O-N 3.11Å; S480-R484 WeakPolarHBondContact O-CB 3.4Å; S480-R484 PolarHBondContact O-N 3.46Å
481E90.8Very high94.3Very high91 Ų9147.5 Ų47.543%0.42524%0.238SC..Hα-helixtrans-57.7-38.3-177.2-172.960.1-160.300112.7V483 R484 Q485 R488E481-V483 PolarHBondContact O-N 3.39Å; E481-R484 WeakPolarHBondContact O-CB 3.4Å; E481-R484 PolarHBondContact O-N 3Å; E481-R484 IonicContact OE2-CZ 2.93Å; E481-R484 IonicContact OE2-NE 3.18Å; E481-R484 IonicContact OE2-NH1 3.78Å; E481-R484 PolarHBondContact OE2-NH1 3.25Å; E481-Q485 PolarHBondContact O-N 3.26Å; E481-R488 IonicContact OE1-CZ 3.91Å; E481-R488 IonicContact OE1-NH1 3.38Å; E481-R488 PolarHBondContact OE1-NH1 2.54Å; E481-R488 IonicContact OE1-NH2 2.75Å
482R87.4Confident94Very high89 Ų8951.7 Ų51.734%0.33625%0.252SS..Hα-helixtrans-59.9-43.6177.5-169.2175.571.7-146.2-4.5112.4L444 S480 N640 E643L444-R482 HydrophobicContact CD1-CG 4.08Å; L444-R482 VanDerWaalsContact CD2-NH2 3.3Å; S480-R482 VanDerWaalsContact C-N 3.26Å; S480-R482 PolarHBondContact O-N 2.86Å; R482-N640 PolarHBondContact NE-OD1 2.98Å; R482-N640 PolarHBondContact NH1-OD1 3.04Å; R482-N640 PolarHBondContact NH2-OD1 2.82Å; R482-E643 IonicContact CZ-OE2 3.62Å; R482-E643 IonicContact NH1-OE2 2.88Å; R482-E643 PolarHBondContact NH1-OE2 2.83Å; R482-E643 IonicContact NH2-OE2 2.9Å; R482-E643 PolarHBondContact NH2-OE2 3.3Å
483V92.5Very high93.8Very high7 Ų751.7 Ų51.74%0.04225%0.252CS..Hα-helixtrans-74-40.6177.4172.30000110.4L444 F446 V479 S480 E481 Q485 Q486 Y487L444-V483 HydrophobicContact CD2-CG2 4.49Å; F446-V483 HydrophobicContact CE2-CG1 3.9Å; F446-V483 HydrophobicContact CZ-CG1 3.9Å; V479-V483 HydrophobicContact CB-CB 4.09Å; V479-V483 HydrophobicContact CB-CG1 3.77Å; V479-V483 HydrophobicContact CG1-CG1 4.08Å; V479-V483 HydrophobicContact CG2-CB 4.17Å; V479-V483 HydrophobicContact CG2-CG1 3.81Å; S480-V483 PolarHBondContact O-N 3.28Å; S480-V483 VanDerWaalsContact O-N 3.11Å; E481-V483 PolarHBondContact O-N 3.39Å; V483-Q485 VanDerWaalsContact C-N 3.28Å; V483-Q485 PolarHBondContact O-N 3.07Å; V483-Q486 PolarHBondContact O-N 3.2Å; V483-Q486 VanDerWaalsContact O-N 3.11Å; V483-Y487 HydrophobicContact CG1-CD2 3.78Å; V483-Y487 HydrophobicContact CG1-CE2 3.48Å; V483-Y487 VanDerWaalsContact CG1-CE2 3.48Å; V483-Y487 WeakPolarHBondContact O-CD2 3.28Å; V483-Y487 PolarHBondContact O-N 2.91Å; V483-Y487 VanDerWaalsContact O-N 3.09Å
484R95.2Very high93.6Very high70 Ų7048.6 Ų48.626%0.26424%0.238SC..Hα-helixtrans-57.9-39.6176.7-169.5-178.2-60.8148.7-2.6112A476 V479 S480 E481 Q486 Y487 R488A476-R484 HydrophobicContact CB-CG 4.49Å; A476-R484 PolarHBondContact O-NE 2.85Å; V479-R484 HydrophobicContact CG2-CB 4.01Å; V479-R484 PolarHBondContact O-NH2 3.34Å; S480-R484 WeakPolarHBondContact O-CB 3.4Å; S480-R484 PolarHBondContact O-N 3.46Å; E481-R484 WeakPolarHBondContact O-CB 3.4Å; E481-R484 PolarHBondContact O-N 3Å; E481-R484 IonicContact OE2-CZ 2.93Å; E481-R484 IonicContact OE2-NE 3.18Å; E481-R484 IonicContact OE2-NH1 3.78Å; E481-R484 PolarHBondContact OE2-NH1 3.25Å; R484-Q486 VanDerWaalsContact C-N 3.34Å; R484-Q486 PolarHBondContact O-N 3.05Å; R484-Y487 PolarHBondContact O-N 3.3Å; R484-R488 WeakPolarHBondContact O-CG 3.45Å; R484-R488 PolarHBondContact O-N 3.06Å
485Q92.5Very high93.4Very high40 Ų4048.5 Ų48.519%0.18723%0.232CC..Hα-helixtrans-59.4-44.7175.9-176.558.544.800111.7E481 V483 Y487 R488 D489E481-Q485 PolarHBondContact O-N 3.26Å; V483-Q485 VanDerWaalsContact C-N 3.28Å; V483-Q485 PolarHBondContact O-N 3.07Å; Q485-Y487 VanDerWaalsContact C-N 3.34Å; Q485-Y487 PolarHBondContact O-N 3.1Å; Q485-R488 PolarHBondContact O-N 2.88Å; Q485-D489 PolarHBondContact NE2-OD1 3.31Å; Q485-D489 PolarHBondContact O-N 2.96Å; Q485-D489 VanDerWaalsContact O-N 3.09Å
486Q93.4Very high93.2Very high12 Ų1250.3 Ų50.36%0.05624%0.239CC..Hα-helixtrans-63.7-41.2177.6-58.1-52.4-4900111.3L444 F446 V483 R484 D489 N490L444-Q486 HydrophobicContact CD1-CG 4.42Å; F446-Q486 HydrophobicContact CD1-CB 3.8Å; F446-Q486 HydrophobicContact CD2-CB 4.2Å; F446-Q486 HydrophobicContact CD2-CG 4.37Å; F446-Q486 HydrophobicContact CE1-CB 3.55Å; F446-Q486 HydrophobicContact CE2-CB 3.98Å; F446-Q486 HydrophobicContact CE2-CG 4.38Å; F446-Q486 HydrophobicContact CG-CB 4.11Å; F446-Q486 HydrophobicContact CZ-CB 3.65Å; V483-Q486 PolarHBondContact O-N 3.2Å; V483-Q486 VanDerWaalsContact O-N 3.11Å; R484-Q486 VanDerWaalsContact C-N 3.34Å; R484-Q486 PolarHBondContact O-N 3.05Å; Q486-D489 PolarHBondContact O-N 3.39Å; Q486-N490 PolarHBondContact O-N 3.07Å; Q486-N490 PolarHBondContact O-ND2 2.91Å
487Y96.3Very high92.9Very high0 Ų049.8 Ų49.80%024%0.235CC..Hα-helixtrans-63.3-43.4173.3-76.3-58.7000112.9F446 L472 I475 A476 V479 V483 R484 Q485 D489 N490 I491 D514F446-Y487 AromaticContact CE1-CD1 3.92Å; F446-Y487 HydrophobicContact CE1-CD1 3.92Å; F446-Y487 HydrophobicContact CE1-CD2 4.4Å; F446-Y487 AromaticContact CE1-CE1 3.83Å; F446-Y487 HydrophobicContact CE1-CE1 3.83Å; F446-Y487 HydrophobicContact CE1-CE2 4.31Å; F446-Y487 HydrophobicContact CE1-CG 4.22Å; F446-Y487 HydrophobicContact CZ-CD1 4.2Å; F446-Y487 AromaticContact CZ-CD2 3.89Å; F446-Y487 HydrophobicContact CZ-CD2 3.89Å; F446-Y487 AromaticContact CZ-CE1 3.98Å; F446-Y487 HydrophobicContact CZ-CE1 3.98Å; F446-Y487 AromaticContact CZ-CE2 3.65Å; F446-Y487 HydrophobicContact CZ-CE2 3.65Å; F446-Y487 HydrophobicContact CZ-CG 4.17Å; F446-Y487 AromaticContact CZ-CZ 3.71Å; L472-Y487 HydrophobicContact CB-CD1 4.36Å; L472-Y487 HydrophobicContact CD2-CD1 3.68Å; L472-Y487 HydrophobicContact CD2-CE1 3.56Å; L472-Y487 HydrophobicContact CG-CD1 4.42Å; I475-Y487 HydrophobicContact CG2-CD2 4.4Å; I475-Y487 HydrophobicContact CG2-CE1 4.4Å; I475-Y487 HydrophobicContact CG2-CE2 3.59Å; I475-Y487 WeakPolarHBondContact CG2-OH 3.17Å; A476-Y487 HydrophobicContact CB-CD2 4.43Å; A476-Y487 HydrophobicContact CB-CG 4.32Å; V479-Y487 HydrophobicContact CG1-CE2 4.46Å; V479-Y487 HydrophobicContact CG2-CD2 4.13Å; V479-Y487 HydrophobicContact CG2-CE2 4.38Å; V483-Y487 HydrophobicContact CG1-CD2 3.78Å; V483-Y487 HydrophobicContact CG1-CE2 3.48Å; V483-Y487 VanDerWaalsContact CG1-CE2 3.48Å; V483-Y487 WeakPolarHBondContact O-CD2 3.28Å; V483-Y487 PolarHBondContact O-N 2.91Å; V483-Y487 VanDerWaalsContact O-N 3.09Å; R484-Y487 PolarHBondContact O-N 3.3Å; Q485-Y487 VanDerWaalsContact C-N 3.34Å; Q485-Y487 PolarHBondContact O-N 3.1Å; Y487-D489 VanDerWaalsContact C-N 3.32Å; Y487-D489 PolarHBondContact O-N 3.46Å; Y487-N490 CarbonylContact O-C 3.56Å; Y487-N490 PolarHBondContact O-N 3.23Å; Y487-N490 VanDerWaalsContact O-N 3.13Å; Y487-I491 WeakPolarHBondContact O-CB 3.37Å; Y487-I491 WeakPolarHBondContact O-CD1 3.48Å; Y487-I491 WeakPolarHBondContact O-CG1 3.4Å; Y487-I491 PolarHBondContact O-N 3.38Å; Y487-D514 PolarHBondContact OH-OD1 3.04Å; Y487-D514 PolarHBondContact OH-OD2 2.88Å
488R94.7Very high92.8Very high115 Ų11548.7 Ų48.743%0.43423%0.231SC..Hα-helixtrans-57-44.7177.7-78.3175.5-179.8155.13.2112.2E481 R484 Q485 N490 I491 R492E481-R488 IonicContact OE1-CZ 3.91Å; E481-R488 IonicContact OE1-NH1 3.38Å; E481-R488 PolarHBondContact OE1-NH1 2.54Å; E481-R488 IonicContact OE1-NH2 2.75Å; R484-R488 WeakPolarHBondContact O-CG 3.45Å; R484-R488 PolarHBondContact O-N 3.06Å; Q485-R488 PolarHBondContact O-N 2.88Å; R488-N490 VanDerWaalsContact C-N 3.29Å; R488-N490 PolarHBondContact O-N 2.93Å; R488-I491 PolarHBondContact O-N 2.86Å; R488-R492 WeakPolarHBondContact O-CB 3.36Å; R488-R492 PolarHBondContact O-N 3.32Å
489D92.3Very high92.8Very high11 Ų1149.4 Ų49.46%0.05923%0.227CC..Hα-helixtrans-62-39.8178.5-66.6-14.9000111.3L224 R231 Q485 Q486 Y487 W493L224-D489 HydrophobicContact CD2-CB 3.53Å; R231-D489 IonicContact CZ-OD2 2.74Å; R231-D489 IonicContact NH1-OD1 2.74Å; R231-D489 IonicContact NH1-OD2 3.05Å; R231-D489 IonicContact NH2-OD1 3.68Å; R231-D489 IonicContact NH2-OD2 3.68Å; R231-D489 PolarHBondContact NH2-OD2 3.19Å; Q485-D489 PolarHBondContact NE2-OD1 3.31Å; Q485-D489 PolarHBondContact O-N 2.96Å; Q485-D489 VanDerWaalsContact O-N 3.09Å; Q486-D489 PolarHBondContact O-N 3.39Å; Y487-D489 VanDerWaalsContact C-N 3.32Å; Y487-D489 PolarHBondContact O-N 3.46Å; D489-W493 PolarHBondContact O-N 3.27Å
490N95.5Very high92.5Very high0 Ų050.4 Ų50.40%023%0.229CC..Hα-helixtrans-76.2-32.5179-73.9-72.2000113.8H220 L472 Q486 Y487 R488 W493 I494 Y512H220-N490 PolarHBondContact CE1-OD1 3Å; H220-N490 VanDerWaalsContact CE1-OD1 3.23Å; H220-N490 PolarHBondContact NE2-OD1 3.32Å; L472-N490 HydrophobicContact CD1-CB 4.07Å; Q486-N490 PolarHBondContact O-N 3.07Å; Q486-N490 PolarHBondContact O-ND2 2.91Å; Y487-N490 CarbonylContact O-C 3.56Å; Y487-N490 PolarHBondContact O-N 3.23Å; Y487-N490 VanDerWaalsContact O-N 3.13Å; R488-N490 VanDerWaalsContact C-N 3.29Å; R488-N490 PolarHBondContact O-N 2.93Å; N490-W493 PolarHBondContact O-N 3.29Å; N490-I494 WeakPolarHBondContact O-CG2 3.48Å; N490-I494 PolarHBondContact O-N 2.89Å; N490-Y512 PolarHBondContact ND2-O 3.44Å; N490-Y512 WeakPolarHBondContact OD1-CA 3.41Å; N490-Y512 WeakPolarHBondContact OD1-CB 3.48Å; N490-Y512 PolarHBondContact OD1-N 3.09Å; N490-Y512 PolarHBondContact OD1-O 3.19Å
491I95.8Very high92.4Very high20 Ų2056.9 Ų56.910%0.10325%0.251CS..Hα-helixtrans-65.6-44.2171.7-70159.8000109.9L472 E473 A476 Y487 R488 W493 I494 R495L472-I491 HydrophobicContact CB-CD1 4.03Å; L472-I491 HydrophobicContact CB-CG1 3.59Å; L472-I491 HydrophobicContact CD1-CG1 4.24Å; E473-I491 HydrophobicContact CG-CD1 3.81Å; E473-I491 HydrophobicContact CG-CG1 4.2Å; E473-I491 HydrophobicContact CG-CG2 4.09Å; E473-I491 WeakPolarHBondContact OE1-CG2 3.36Å; A476-I491 HydrophobicContact CB-CD1 4.2Å; Y487-I491 WeakPolarHBondContact O-CB 3.37Å; Y487-I491 WeakPolarHBondContact O-CD1 3.48Å; Y487-I491 WeakPolarHBondContact O-CG1 3.4Å; Y487-I491 PolarHBondContact O-N 3.38Å; R488-I491 PolarHBondContact O-N 2.86Å; I491-W493 VanDerWaalsContact C-N 3.33Å; I491-W493 PolarHBondContact O-N 3.49Å; I491-I494 WeakPolarHBondContact O-CG2 3.48Å; I491-I494 PolarHBondContact O-N 2.97Å; I491-R495 WeakPolarHBondContact O-CB 3.38Å; I491-R495 VanDerWaalsContact O-CG 3.3Å; I491-R495 WeakPolarHBondContact O-CG 3.34Å; I491-R495 PolarHBondContact O-N 3.29Å; I491-R495 VanDerWaalsContact O-N 3.14Å
492R92.3Very high92.3Very high103 Ų10352.7 Ų52.739%0.38923%0.232SC..Hα-helixtrans-58.4-48.6174.4179.8178.3175-166.1-7110.5I262 R488 E496I262-R492 PolarHBondContact O-NH2 3.4Å; R488-R492 WeakPolarHBondContact O-CB 3.36Å; R488-R492 PolarHBondContact O-N 3.32Å; R492-E496 IonicContact NE-OE1 2.81Å; R492-E496 IonicContact NE-OE2 2.68Å; R492-E496 WeakPolarHBondContact O-CG 3.48Å; R492-E496 PolarHBondContact O-N 2.87Å
493W93.7Very high92.5Very high1 Ų150.4 Ų50.40%0.00423%0.228CC..Hα-helixtrans-56.5-55177166.3-107.1000112.6V219 H220 M223 I262 D489 N490 I491 R495 E496 A497 M502 I510V219-W493 HydrophobicContact CB-CH2 4.21Å; V219-W493 HydrophobicContact CG1-CH2 4.06Å; V219-W493 HydrophobicContact CG1-CZ3 3.94Å; H220-W493 HydrophobicContact CB-CD2 4.14Å; H220-W493 HydrophobicContact CB-CE3 4.46Å; H220-W493 HydrophobicContact CB-CH2 3.92Å; H220-W493 HydrophobicContact CB-CZ2 3.64Å; H220-W493 HydrophobicContact CB-CZ3 4.35Å; H220-W493 AromaticContact CD2-CD1 3.44Å; H220-W493 VanDerWaalsContact CD2-CD1 3.44Å; H220-W493 AromaticContact CD2-CD2 3.56Å; H220-W493 AromaticContact CD2-CE2 3.75Å; H220-W493 AromaticContact CD2-CG 3.36Å; H220-W493 AromaticContact CD2-NE1 3.65Å; H220-W493 AromaticContact CG-CE2 3.96Å; H220-W493 AromaticContact CG-NE1 3.96Å; H220-W493 AromaticContact NE2-CD1 3.97Å; M223-W493 HydrophobicContact CE-CB 3.76Å; M223-W493 HydrophobicContact CE-CD2 4.34Å; M223-W493 HydrophobicContact CE-CE3 3.93Å; M223-W493 HydrophobicContact CE-CG 4.3Å; I262-W493 HydrophobicContact CD1-CZ3 4.12Å; D489-W493 PolarHBondContact O-N 3.27Å; N490-W493 PolarHBondContact O-N 3.29Å; I491-W493 VanDerWaalsContact C-N 3.33Å; I491-W493 PolarHBondContact O-N 3.49Å; W493-R495 VanDerWaalsContact C-N 3.26Å; W493-R495 PolarHBondContact O-N 3.21Å; W493-E496 PolarHBondContact O-N 3.2Å; W493-A497 HydrophobicContact CD2-CB 4.3Å; W493-A497 HydrophobicContact CZ2-CB 4.11Å; W493-A497 WeakPolarHBondContact O-CB 3.41Å; W493-A497 PolarHBondContact O-N 3.33Å; W493-M502 HydrophobicContact CH2-CE 3.14Å; W493-M502 HydrophobicContact CH2-SD 4.01Å; W493-M502 HydrophobicContact CZ2-CE 3.88Å; W493-M502 HydrophobicContact CZ3-CE 3.68Å; W493-M502 HydrophobicContact CZ3-SD 4.47Å; W493-I510 PolarHBondContact NE1-O 3.27Å
494I94.9Very high92.5Very high5 Ų552 Ų523%0.02624%0.237CC..Hα-helixtrans-64.9-32.6-172.4-165.461.1000111.9W451 D465 A468 A469 N490 I491 E496 R509 L511W451-I494 HydrophobicContact CH2-CD1 3.84Å; W451-I494 HydrophobicContact CZ2-CD1 4.33Å; D465-I494 HydrophobicContact CB-CD1 4.14Å; D465-I494 HydrophobicContact CB-CG1 4.27Å; D465-I494 WeakPolarHBondContact OD1-CD1 3.4Å; A468-I494 HydrophobicContact CB-CG1 4.28Å; A469-I494 HydrophobicContact CB-CG2 3.79Å; N490-I494 WeakPolarHBondContact O-CG2 3.48Å; N490-I494 PolarHBondContact O-N 2.89Å; I491-I494 WeakPolarHBondContact O-CG2 3.48Å; I491-I494 PolarHBondContact O-N 2.97Å; I494-E496 VanDerWaalsContact C-N 3.31Å; I494-E496 PolarHBondContact O-N 3.16Å; I494-R509 HydrophobicContact CD1-CG 3.43Å; I494-R509 VanDerWaalsContact CD1-CG 3.43Å; I494-L511 HydrophobicContact CB-CD2 4.43Å; I494-L511 HydrophobicContact CD1-CD2 4.2Å; I494-L511 HydrophobicContact CG1-CD2 4.28Å
495R93.7Very high92.4Very high136 Ų13650.3 Ų50.351%0.51324%0.241SC..Hα-helixtrans-71.9-21.5175.4-71.2-178.3168.1-77.53.3113.8A469 E473 I491 W493A469-R495 HydrophobicContact CB-CG 4.48Å; E473-R495 IonicContact OE1-CZ 3.53Å; E473-R495 IonicContact OE1-NE 2.8Å; E473-R495 PolarHBondContact OE1-NE 3.32Å; E473-R495 IonicContact OE1-NH2 3.2Å; E473-R495 PolarHBondContact OE1-NH2 2.9Å; E473-R495 IonicContact OE2-NH2 3.44Å; E473-R495 PolarHBondContact OE2-NH2 2.87Å; I491-R495 WeakPolarHBondContact O-CB 3.38Å; I491-R495 VanDerWaalsContact O-CG 3.3Å; I491-R495 WeakPolarHBondContact O-CG 3.34Å; I491-R495 PolarHBondContact O-N 3.29Å; I491-R495 VanDerWaalsContact O-N 3.14Å; W493-R495 VanDerWaalsContact C-N 3.26Å; W493-R495 PolarHBondContact O-N 3.21Å
496E90.3Very high92.7Very high54 Ų5448.7 Ų48.725%0.25223%0.234SC..Hα-helixtrans-104.1-26-178.5-69.8-179.8177.700113.1R492 W493 I494 G498 K499 H500R492-E496 IonicContact NE-OE1 2.81Å; R492-E496 IonicContact NE-OE2 2.68Å; R492-E496 WeakPolarHBondContact O-CG 3.48Å; R492-E496 PolarHBondContact O-N 2.87Å; W493-E496 PolarHBondContact O-N 3.2Å; I494-E496 VanDerWaalsContact C-N 3.31Å; I494-E496 PolarHBondContact O-N 3.16Å; E496-G498 VanDerWaalsContact C-N 3.29Å; E496-G498 PolarHBondContact O-N 2.94Å; E496-G498 VanDerWaalsContact O-N 3.14Å; E496-K499 WeakPolarHBondContact O-CB 3.46Å; E496-K499 PolarHBondContact O-N 3.26Å; E496-H500 PolarHBondContact O-CD2 3.05Å; E496-H500 VanDerWaalsContact O-CD2 3.27Å
497A91.4Very high92.9Very high0 Ų049.7 Ų49.70%024%0.239CC..Hα-helixtrans-53.4-42-170.600000113.4W493 K499 H500 M502W493-A497 HydrophobicContact CD2-CB 4.3Å; W493-A497 HydrophobicContact CZ2-CB 4.11Å; W493-A497 WeakPolarHBondContact O-CB 3.41Å; W493-A497 PolarHBondContact O-N 3.33Å; A497-K499 VanDerWaalsContact C-N 3.32Å; A497-K499 PolarHBondContact O-N 3.37Å; A497-H500 PolarHBondContact O-N 2.94Å; A497-M502 HydrophobicContact CB-CE 4.38Å
498G90.8Very high93Very high43 Ų4349.7 Ų49.744%0.44324%0.239SC..G310 helixtrans-60.8-36.4176.700000113.8E496 H500 K501E496-G498 VanDerWaalsContact C-N 3.29Å; E496-G498 PolarHBondContact O-N 2.94Å; E496-G498 VanDerWaalsContact O-N 3.14Å; G498-H500 PolarHBondContact O-N 2.99Å; G498-K501 PolarHBondContact O-N 3.33Å
499K91.3Very high93.2Very high161 Ų16144.4 Ų44.470%0.722%0.219SC*.G310 helixtrans-67.3-26.6-179-56.7175.1-173.2169.40112.2E496 A497E496-K499 WeakPolarHBondContact O-CB 3.46Å; E496-K499 PolarHBondContact O-N 3.26Å; A497-K499 VanDerWaalsContact C-N 3.32Å; A497-K499 PolarHBondContact O-N 3.37Å
500H87.8Confident93.4Very high52 Ų5244.1 Ų44.124%0.24122%0.218CC..G310 helixtrans-84.2-6.1-179-63.5-60.2000114.3E496 A497 G498 M502E496-H500 PolarHBondContact O-CD2 3.05Å; E496-H500 VanDerWaalsContact O-CD2 3.27Å; A497-H500 PolarHBondContact O-N 2.94Å; G498-H500 PolarHBondContact O-N 2.99Å; H500-M502 VanDerWaalsContact C-N 3.29Å; H500-M502 HydrophobicContact CB-CE 3.79Å; H500-M502 HydrophobicContact CB-CG 3.84Å; H500-M502 HydrophobicContact CB-SD 3.96Å; H500-M502 PolarHBondContact O-N 3.44Å
501K88.8Confident93.5Very high185 Ų18544.1 Ų44.180%0.80422%0.218SC*.THydrogen-bonded Turntrans49.744.4175.3-58-176.1179.6-178.10113.7G498 V503G498-K501 PolarHBondContact O-N 3.33Å; K501-V503 VanDerWaalsContact C-N 3.35Å
502M87.6Confident93.5Very high2 Ų243.7 Ų43.71%0.0122%0.215CC..  trans-87.60.9-175.1-62.5175-64.900114.5Q216 V219 K258 W285 W493 A497 H500 V504Q216-M502 HydrophobicContact CB-CB 3.98Å; V219-M502 HydrophobicContact CB-SD 4.04Å; V219-M502 HydrophobicContact CG1-SD 3.8Å; V219-M502 HydrophobicContact CG2-SD 4.02Å; K258-M502 HydrophobicContact CG-SD 4.49Å; W285-M502 HydrophobicContact CZ2-CG 4.37Å; W493-M502 HydrophobicContact CH2-CE 3.14Å; W493-M502 HydrophobicContact CH2-SD 4.01Å; W493-M502 HydrophobicContact CZ2-CE 3.88Å; W493-M502 HydrophobicContact CZ3-CE 3.68Å; W493-M502 HydrophobicContact CZ3-SD 4.47Å; A497-M502 HydrophobicContact CB-CE 4.38Å; H500-M502 VanDerWaalsContact C-N 3.29Å; H500-M502 HydrophobicContact CB-CE 3.79Å; H500-M502 HydrophobicContact CB-CG 3.84Å; H500-M502 HydrophobicContact CB-SD 3.96Å; H500-M502 PolarHBondContact O-N 3.44Å; M502-V504 PolarHBondContact O-N 3.32Å
503V92.9Very high93.7Very high42 Ų4238.8 Ų38.826%0.25520%0.196SC..  trans-70.4127.6-179.91800000109.3L461 K501 S506L461-V503 HydrophobicContact CD2-CG2 3.69Å; K501-V503 VanDerWaalsContact C-N 3.35Å; V503-S506 WeakPolarHBondContact CG1-O 3.31Å
504V90.8Very high93.9Very high41 Ų4139.7 Ų39.725%0.24820%0.201CC..  trans-135.8130175.3-177.80000108.1A114 V115 M502A114-V504 HydrophobicContact CB-CG1 3.86Å; A114-V504 VanDerWaalsContact O-CG1 3.24Å; A114-V504 WeakPolarHBondContact O-CG1 3.48Å; V115-V504 HydrophobicContact CG2-CG1 4Å; M502-V504 PolarHBondContact O-N 3.32Å
505G94.8Very high94Very high33 Ų3340.7 Ų40.734%0.3421%0.206SC..SBendtrans76-123.3-173.300000111.4
506S97.4Very high94.2Very high6 Ų638.8 Ų38.84%0.04220%0.201CC..SBendtrans-64.4150.1179.259.40000113.4N109 V503 A508N109-S506 VanDerWaalsContact CG-OG 3.27Å; N109-S506 PolarHBondContact ND2-OG 3.49Å; N109-S506 VanDerWaalsContact OD1-CB 3.25Å; N109-S506 WeakPolarHBondContact OD1-CB 3.44Å; N109-S506 PolarHBondContact OD1-N 3.48Å; N109-S506 PolarHBondContact OD1-OG 3.44Å; V503-S506 WeakPolarHBondContact CG1-O 3.31Å; S506-A508 PolarHBondContact O-N 3.19Å; S506-A508 VanDerWaalsContact O-N 3.07Å
507Q98.3Very high94.5Very high33 Ų3336.2 Ų36.215%0.15419%0.189CC..EExtended strand (participates in β ladder)trans-72101.6174.5-63.7-57.8-31.400109.3V452 C453 G456 L461V452-Q507 CarbonylContact C-O 3.54Å; V452-Q507 WeakPolarHBondContact CA-O 3.38Å; C453-Q507 HydrophobicContact CB-CB 4.16Å; C453-Q507 PolarHBondContact N-O 2.73Å; G456-Q507 WeakPolarHBondContact O-CG 3.47Å; L461-Q507 HydrophobicContact CB-CB 4.29Å; L461-Q507 HydrophobicContact CD2-CB 4.35Å
508A98.2Very high94.9Very high0 Ų036.3 Ų36.30%019%0.189CC..EExtended strand (participates in β ladder)trans-141153.6-167.500000112.1I213 Q216 W451 V452 S506I213-A508 HydrophobicContact CB-CB 3.61Å; I213-A508 HydrophobicContact CD1-CB 4.05Å; I213-A508 HydrophobicContact CG1-CB 4.17Å; I213-A508 HydrophobicContact CG2-CB 3.65Å; Q216-A508 PolarHBondContact NE2-O 3.04Å; Q216-A508 PolarHBondContact OE1-O 3.23Å; W451-A508 CarbonylContact O-C 3.57Å; W451-A508 WeakPolarHBondContact O-CA 3.26Å; W451-A508 WeakPolarHBondContact O-CB 3.47Å; V452-A508 HydrophobicContact CG2-CB 3.83Å; S506-A508 PolarHBondContact O-N 3.19Å; S506-A508 VanDerWaalsContact O-N 3.07Å
509R98.1Very high95.2Very high5 Ų534.7 Ų34.72%0.01917%0.171CC..EExtended strand (participates in β ladder)trans-142.3161.2175.4-17466.467.6-140.53.7110.9Q216 R450 W451 L461 D465 I494Q216-R509 VanDerWaalsContact OE1-NH1 3.17Å; R450-R509 CarbonylContact C-O 3.6Å; R450-R509 VanDerWaalsContact CA-O 3.23Å; R450-R509 WeakPolarHBondContact CA-O 3.25Å; R450-R509 WeakPolarHBondContact CB-O 3.41Å; W451-R509 HydrophobicContact CD2-CB 4.03Å; W451-R509 HydrophobicContact CE3-CB 4.34Å; W451-R509 HydrophobicContact CH2-CB 3.8Å; W451-R509 HydrophobicContact CH2-CG 3.43Å; W451-R509 VanDerWaalsContact CH2-CG 3.43Å; W451-R509 HydrophobicContact CZ2-CB 3.42Å; W451-R509 VanDerWaalsContact CZ2-CB 3.42Å; W451-R509 HydrophobicContact CZ2-CG 3.47Å; W451-R509 VanDerWaalsContact CZ2-CG 3.47Å; W451-R509 HydrophobicContact CZ3-CB 4.23Å; W451-R509 HydrophobicContact CZ3-CG 4.05Å; W451-R509 PolarHBondContact N-O 2.84Å; W451-R509 PolarHBondContact O-N 2.75Å; L461-R509 HydrophobicContact CD1-CB 3.9Å; D465-R509 VanDerWaalsContact OD1-CG 3.24Å; D465-R509 WeakPolarHBondContact OD1-CG 3.46Å; D465-R509 IonicContact OD1-CZ 2.94Å; D465-R509 IonicContact OD1-NE 3.85Å; D465-R509 PolarHBondContact OD1-NE 3Å; D465-R509 IonicContact OD1-NH2 2.62Å; D465-R509 IonicContact OD2-CZ 3.53Å; D465-R509 IonicContact OD2-NE 2.76Å; D465-R509 PolarHBondContact OD2-NE 3.07Å; D465-R509 VanDerWaalsContact OD2-NE 3.16Å; D465-R509 IonicContact OD2-NH2 3.07Å; D465-R509 PolarHBondContact OD2-NH2 3.06Å; I494-R509 HydrophobicContact CD1-CG 3.43Å; I494-R509 VanDerWaalsContact CD1-CG 3.43Å
510I97Very high95.6Very high5 Ų529.3 Ų29.33%0.02615%0.153CC..EExtended strand (participates in β ladder)trans-141.9150.6174.4-173.4171.2000109.7I213 Q216 H220 P448 F449 R450 W493I213-I510 HydrophobicContact CD1-CB 4.06Å; I213-I510 HydrophobicContact CD1-CG2 4.32Å; Q216-I510 HydrophobicContact CG-CG2 4.3Å; H220-I510 HydrophobicContact CB-CG2 4.3Å; P448-I510 HydrophobicContact CB-CD1 4.1Å; F449-I510 CarbonylContact O-C 3.59Å; F449-I510 WeakPolarHBondContact O-CA 3.45Å; R450-I510 HydrophobicContact CB-CB 4.17Å; R450-I510 HydrophobicContact CB-CG1 4.17Å; W493-I510 PolarHBondContact NE1-O 3.27Å
511L96.9Very high96.1Very high0 Ų026.8 Ų26.80%014%0.141CC..EExtended strand (participates in β ladder)trans-153.4177.316555.580.6000108.5F449 W451 A468 L472 I494 I521F449-L511 HydrophobicContact CB-CD1 4.22Å; F449-L511 HydrophobicContact CD1-CD1 4.39Å; F449-L511 PolarHBondContact N-O 3.23Å; F449-L511 PolarHBondContact O-N 3.12Å; F449-L511 VanDerWaalsContact O-O 3.14Å; W451-L511 HydrophobicContact CH2-CD2 3.96Å; W451-L511 HydrophobicContact CZ3-CD2 3.9Å; W451-L511 HydrophobicContact CZ3-CG 4.07Å; A468-L511 HydrophobicContact CB-CD2 3.97Å; L472-L511 HydrophobicContact CD1-CD1 4.4Å; L472-L511 HydrophobicContact CD1-CD2 4.05Å; I494-L511 HydrophobicContact CB-CD2 4.43Å; I494-L511 HydrophobicContact CD1-CD2 4.2Å; I494-L511 HydrophobicContact CG1-CD2 4.28Å; L511-I521 HydrophobicContact CD1-CD1 4.24Å
512Y96.9Very high96.6Very high10 Ų1018 Ų184%0.03910%0.103CC..EExtended strand (participates in β ladder)trans-102.9136.4169.8-86.932.6000110.8H220 L224 M438 I441 F442 G447 P448 N490 H545H220-Y512 AromaticContact CE1-CD1 3.3Å; H220-Y512 WeakPolarHBondContact CE1-CD1 3.39Å; H220-Y512 AromaticContact CE1-CG 3.74Å; H220-Y512 PolarHBondContact CE1-N 3.48Å; H220-Y512 AromaticContact ND1-CD1 3.6Å; H220-Y512 AromaticContact ND1-CE1 3.95Å; L224-Y512 HydrophobicContact CD1-CD1 4.47Å; L224-Y512 HydrophobicContact CD1-CD2 4.08Å; L224-Y512 HydrophobicContact CD1-CG 3.98Å; M438-Y512 HydrophobicContact CE-CD2 3.98Å; M438-Y512 HydrophobicContact CE-CE2 3.2Å; I441-Y512 HydrophobicContact CG2-CD2 4.3Å; F442-Y512 HydrophobicContact CE1-CE2 4.11Å; G447-Y512 VanDerWaalsContact CA-CD2 3.5Å; G447-Y512 WeakPolarHBondContact O-CA 3.22Å; P448-Y512 HydrophobicContact CB-CD1 4.29Å; P448-Y512 HydrophobicContact CB-CE1 3.8Å; P448-Y512 HydrophobicContact CG-CE1 4.34Å; N490-Y512 PolarHBondContact ND2-O 3.44Å; N490-Y512 WeakPolarHBondContact OD1-CA 3.41Å; N490-Y512 WeakPolarHBondContact OD1-CB 3.48Å; N490-Y512 PolarHBondContact OD1-N 3.09Å; N490-Y512 PolarHBondContact OD1-O 3.19Å; Y512-H545 PolarHBondContact OH-CD2 2.86Å; Y512-H545 VanDerWaalsContact OH-CD2 3.32Å
513S97.3Very high97.1Very high0 Ų019.6 Ų19.60%011%0.112CC..EExtended strand (participates in β ladder)trans-151149.7175.9-172.80000111.3G447 G517 R518G447-S513 PolarHBondContact N-O 3.47Å; G447-S513 PolarHBondContact O-N 3.49Å; G447-S513 VanDerWaalsContact O-N 3.09Å; S513-G517 VanDerWaalsContact OG-C 3.24Å; S513-G517 WeakPolarHBondContact OG-CA 3.09Å; S513-R518 PolarHBondContact O-NE 3.05Å; S513-R518 PolarHBondContact O-NH2 2.92Å; S513-R518 PolarHBondContact OG-N 2.82Å
514D97.3Very high97.4Very high21 Ų2119 Ų1911%0.11211%0.111CC..  trans-74.9-179.9169.771.523.2000112.4G445 F446 Y487 K516 G517 R518G445-D514 WeakPolarHBondContact O-CA 3.16Å; F446-D514 HydrophobicContact CD2-CB 3.82Å; F446-D514 HydrophobicContact CE2-CB 3.75Å; F446-D514 HydrophobicContact CG-CB 4.26Å; F446-D514 HydrophobicContact CZ-CB 4.14Å; Y487-D514 PolarHBondContact OH-OD1 3.04Å; Y487-D514 PolarHBondContact OH-OD2 2.88Å; D514-K516 VanDerWaalsContact C-N 3.33Å; D514-K516 PolarHBondContact O-N 3.47Å; D514-K516 PolarHBondContact OD1-N 3.36Å; D514-G517 PolarHBondContact O-N 3.11Å; D514-G517 PolarHBondContact OD1-N 2.74Å; D514-R518 WeakPolarHBondContact O-CB 3.47Å; D514-R518 VanDerWaalsContact O-CG 3.25Å; D514-R518 WeakPolarHBondContact O-CG 3.44Å; D514-R518 PolarHBondContact O-N 3.43Å
515Q97.1Very high97.8Very high25 Ų2517 Ų1712%0.11710%0.099CC..Hα-helixtrans-48.6-50.5178.6-177.8-175.8-19.200113.2R518 V519 N623 V626 S627Q515-R518 PolarHBondContact O-N 3.11Å; Q515-V519 WeakPolarHBondContact O-CG2 3.34Å; Q515-V519 PolarHBondContact O-N 3.31Å; Q515-N623 PolarHBondContact NE2-OD1 2.7Å; Q515-V626 HydrophobicContact CB-CB 3.91Å; Q515-V626 HydrophobicContact CB-CG1 3.72Å; Q515-V626 HydrophobicContact CB-CG2 4.37Å; Q515-V626 HydrophobicContact CG-CB 4.37Å; Q515-S627 PolarHBondContact OE1-OG 2.97Å
516K96.4Very high98Very high97 Ų9715.8 Ų15.842%0.4229%0.085SC..Hα-helixtrans-66.8-47.7-174.4-174.4171.4-172.2163.30110.1I475 D514 R518 V519 C520 E651I475-K516 HydrophobicContact CD1-CG 4.37Å; D514-K516 VanDerWaalsContact C-N 3.33Å; D514-K516 PolarHBondContact O-N 3.47Å; D514-K516 PolarHBondContact OD1-N 3.36Å; K516-R518 PolarHBondContact O-N 3.2Å; K516-V519 PolarHBondContact O-N 3.46Å; K516-C520 WeakPolarHBondContact O-CB 3.47Å; K516-C520 PolarHBondContact O-N 3.47Å; K516-C520 PolarHBondContact O-SG 3.39Å; K516-E651 IonicContact NZ-OE1 2.69Å
517G97.9Very high98Very high0 Ų020.2 Ų20.20%011%0.105CC..Hα-helixtrans-64.9-39.9178.300000112.8S513 D514 V519 C520 I521S513-G517 VanDerWaalsContact OG-C 3.24Å; S513-G517 WeakPolarHBondContact OG-CA 3.09Å; D514-G517 PolarHBondContact O-N 3.11Å; D514-G517 PolarHBondContact OD1-N 2.74Å; G517-V519 PolarHBondContact O-N 2.86Å; G517-C520 PolarHBondContact O-N 2.67Å; G517-I521 WeakPolarHBondContact O-CB 3.45Å; G517-I521 WeakPolarHBondContact O-CD1 3.29Å; G517-I521 WeakPolarHBondContact O-CG1 3.33Å; G517-I521 PolarHBondContact O-N 3.02Å
518R98.6Very high98.1Very high1 Ų118.7 Ų18.70%0.00410%0.097CC..Hα-helixtrans-60-47.9175.8-69.5-174.4-161.7-164.75.8111.6G447 F449 S513 D514 Q515 K516 A522 D546 L622 D625G447-R518 PolarHBondContact O-NH2 2.7Å; F449-R518 HydrophobicContact CB-CG 4.09Å; F449-R518 HydrophobicContact CD2-CB 3.82Å; F449-R518 HydrophobicContact CD2-CG 3.5Å; F449-R518 VanDerWaalsContact CD2-CG 3.5Å; F449-R518 HydrophobicContact CE2-CB 3.91Å; F449-R518 HydrophobicContact CE2-CG 4.13Å; F449-R518 HydrophobicContact CG-CG 3.98Å; S513-R518 PolarHBondContact O-NE 3.05Å; S513-R518 PolarHBondContact O-NH2 2.92Å; S513-R518 PolarHBondContact OG-N 2.82Å; D514-R518 WeakPolarHBondContact O-CB 3.47Å; D514-R518 VanDerWaalsContact O-CG 3.25Å; D514-R518 WeakPolarHBondContact O-CG 3.44Å; D514-R518 PolarHBondContact O-N 3.43Å; Q515-R518 PolarHBondContact O-N 3.11Å; K516-R518 PolarHBondContact O-N 3.2Å; R518-A522 VanDerWaalsContact O-CB 3.29Å; R518-A522 WeakPolarHBondContact O-CB 3.37Å; R518-A522 PolarHBondContact O-N 3.34Å; R518-D546 IonicContact CZ-OD1 2.87Å; R518-D546 IonicContact CZ-OD2 2.92Å; R518-D546 IonicContact NH1-OD1 2.89Å; R518-D546 IonicContact NH1-OD2 2.7Å; R518-D546 PolarHBondContact NH1-OD2 2.88Å; R518-D546 IonicContact NH2-OD1 3.79Å; R518-D546 PolarHBondContact NH2-OD1 3.31Å; R518-D546 IonicContact NH2-OD2 3.36Å; R518-D546 PolarHBondContact NH2-OD2 3.38Å; R518-L622 HydrophobicContact CB-CD1 4.3Å; R518-L622 HydrophobicContact CB-CD2 4.46Å; R518-D625 IonicContact NH1-OD2 3.9Å; R518-D625 PolarHBondContact NH1-OD2 3.16Å
519V98.4Very high98.1Very high10 Ų1019.6 Ų19.66%0.06110%0.103CC..Hα-helixtrans-63.5-48.7178.61720000110.7Q515 K516 G517 I521 A522 L523 R619 L622Q515-V519 WeakPolarHBondContact O-CG2 3.34Å; Q515-V519 PolarHBondContact O-N 3.31Å; K516-V519 PolarHBondContact O-N 3.46Å; G517-V519 PolarHBondContact O-N 2.86Å; V519-I521 PolarHBondContact O-N 3.14Å; V519-A522 PolarHBondContact O-N 2.88Å; V519-L523 HydrophobicContact CG1-CD1 3.72Å; V519-L523 HydrophobicContact CG1-CG 4.31Å; V519-L523 WeakPolarHBondContact O-CB 3.41Å; V519-L523 WeakPolarHBondContact O-CG 3.47Å; V519-L523 PolarHBondContact O-N 3.2Å; V519-R619 HydrophobicContact CG1-CG 4.28Å; V519-L622 HydrophobicContact CG2-CB 3.78Å; V519-L622 HydrophobicContact CG2-CD1 4.48Å
520C98.6Very high98.1Very high47 Ų4721.9 Ų21.932%0.31812%0.123SC..Hα-helixtrans-62.3-43.3-179.2-720000112.5V471 I475 K516 G517 L523 A524V471-C520 HydrophobicContact CG1-CB 3.51Å; I475-C520 HydrophobicContact CD1-CB 4.07Å; K516-C520 WeakPolarHBondContact O-CB 3.47Å; K516-C520 PolarHBondContact O-N 3.47Å; K516-C520 PolarHBondContact O-SG 3.39Å; G517-C520 PolarHBondContact O-N 2.67Å; C520-L523 PolarHBondContact O-N 3.26Å; C520-A524 WeakPolarHBondContact O-CB 3.36Å; C520-A524 PolarHBondContact O-N 2.87Å
521I98.8Very high98.2Very high0 Ų025.9 Ų25.90%015%0.145CC..Hα-helixtrans-64.6-47.5177.1-64.6165.7000110.3F449 A468 V471 L472 L511 G517 V519 L523 A524 I525F449-I521 HydrophobicContact CD1-CD1 4.45Å; F449-I521 HydrophobicContact CD1-CG2 4.44Å; F449-I521 HydrophobicContact CE1-CB 3.95Å; F449-I521 HydrophobicContact CE1-CD1 4.45Å; F449-I521 HydrophobicContact CE1-CG2 3.54Å; F449-I521 HydrophobicContact CZ-CB 4.29Å; F449-I521 HydrophobicContact CZ-CG2 4.16Å; A468-I521 HydrophobicContact CB-CD1 4.39Å; A468-I521 HydrophobicContact CB-CG2 4.28Å; V471-I521 HydrophobicContact CB-CG1 4.02Å; V471-I521 HydrophobicContact CG1-CG1 3.7Å; L472-I521 HydrophobicContact CD2-CD1 3.78Å; L472-I521 HydrophobicContact CG-CD1 4.22Å; L511-I521 HydrophobicContact CD1-CD1 4.24Å; G517-I521 WeakPolarHBondContact O-CB 3.45Å; G517-I521 WeakPolarHBondContact O-CD1 3.29Å; G517-I521 WeakPolarHBondContact O-CG1 3.33Å; G517-I521 PolarHBondContact O-N 3.02Å; V519-I521 PolarHBondContact O-N 3.14Å; I521-L523 VanDerWaalsContact C-N 3.31Å; I521-L523 PolarHBondContact O-N 3.33Å; I521-A524 PolarHBondContact O-N 3.25Å; I521-I525 HydrophobicContact CG2-CD1 3.67Å; I521-I525 HydrophobicContact CG2-CG1 4.19Å; I521-I525 WeakPolarHBondContact O-CB 3.45Å; I521-I525 WeakPolarHBondContact O-CG1 3.41Å; I521-I525 PolarHBondContact O-N 2.87Å
522A98.8Very high98.2Very high0 Ų028.6 Ų28.60%017%0.172CC..Hα-helixtrans-58.8-43.3179.500000111.9F449 R518 V519 N526 L608 A618 L622F449-A522 HydrophobicContact CZ-CB 4.25Å; R518-A522 VanDerWaalsContact O-CB 3.29Å; R518-A522 WeakPolarHBondContact O-CB 3.37Å; R518-A522 PolarHBondContact O-N 3.34Å; V519-A522 PolarHBondContact O-N 2.88Å; A522-N526 WeakPolarHBondContact O-CB 3.25Å; A522-N526 PolarHBondContact O-N 3.3Å; A522-L608 HydrophobicContact CB-CD1 4.22Å; A522-L608 VanDerWaalsContact O-CD1 3.27Å; A522-L608 WeakPolarHBondContact O-CD1 3.36Å; A522-A618 HydrophobicContact CB-CB 4.22Å; A522-L622 HydrophobicContact CB-CD1 3.67Å
523L98.9Very high98.3Very high36 Ų3633.8 Ų33.819%0.18819%0.192CC..Hα-helixtrans-66.7-41.6177.3-66.5172.5000112.3V519 C520 I521 N526 Q527 A615V519-L523 HydrophobicContact CG1-CD1 3.72Å; V519-L523 HydrophobicContact CG1-CG 4.31Å; V519-L523 WeakPolarHBondContact O-CB 3.41Å; V519-L523 WeakPolarHBondContact O-CG 3.47Å; V519-L523 PolarHBondContact O-N 3.2Å; C520-L523 PolarHBondContact O-N 3.26Å; I521-L523 VanDerWaalsContact C-N 3.31Å; I521-L523 PolarHBondContact O-N 3.33Å; L523-N526 PolarHBondContact O-N 2.84Å; L523-Q527 WeakPolarHBondContact O-CB 3.39Å; L523-Q527 PolarHBondContact O-N 3.42Å; L523-A615 HydrophobicContact CD2-CB 3.69Å
524A98.9Very high98.4Very high29 Ų2933.8 Ų33.824%0.2419%0.192CC..Hα-helixtrans-66.7-38178.400000112.3I467 V471 C520 I521 A528I467-A524 HydrophobicContact CG2-CB 3.55Å; V471-A524 HydrophobicContact CG2-CB 3.98Å; C520-A524 WeakPolarHBondContact O-CB 3.36Å; C520-A524 PolarHBondContact O-N 2.87Å; I521-A524 PolarHBondContact O-N 3.25Å; A524-A528 WeakPolarHBondContact O-CB 3.49Å; A524-A528 PolarHBondContact O-N 2.85Å
525I98.9Very high98.4Very high0 Ų036.6 Ų36.60%021%0.213CC..Hα-helixtrans-65.7-46.8172.3-70.4176.8000110.2W451 T464 I467 I521 Q527 A528 V529 V538 I540 L608W451-I525 HydrophobicContact CD2-CD1 4.36Å; W451-I525 HydrophobicContact CG-CD1 4.38Å; T464-I525 HydrophobicContact CG2-CD1 4.31Å; T464-I525 HydrophobicContact CG2-CG1 4.26Å; T464-I525 HydrophobicContact CG2-CG2 4.43Å; I467-I525 HydrophobicContact CG2-CG1 4.2Å; I521-I525 HydrophobicContact CG2-CD1 3.67Å; I521-I525 HydrophobicContact CG2-CG1 4.19Å; I521-I525 WeakPolarHBondContact O-CB 3.45Å; I521-I525 WeakPolarHBondContact O-CG1 3.41Å; I521-I525 PolarHBondContact O-N 2.87Å; I525-Q527 VanDerWaalsContact C-N 3.3Å; I525-Q527 PolarHBondContact O-N 3.39Å; I525-A528 WeakPolarHBondContact O-CA 3.27Å; I525-A528 WeakPolarHBondContact O-CB 3.37Å; I525-A528 PolarHBondContact O-N 3.36Å; I525-V529 WeakPolarHBondContact O-CG2 3.29Å; I525-V529 PolarHBondContact O-N 3.17Å; I525-V538 HydrophobicContact CG2-CB 3.69Å; I525-V538 HydrophobicContact CG2-CG1 3.88Å; I525-V538 HydrophobicContact CG2-CG2 3.72Å; I525-I540 HydrophobicContact CD1-CD1 4.33Å; I525-L608 HydrophobicContact CB-CD1 4.11Å; I525-L608 HydrophobicContact CG2-CD1 3.85Å
526N98.9Very high98.5Very high7 Ų735.8 Ų35.84%0.03721%0.21CC..Hα-helixtrans-59.2-42.8178.3-166.168.5000111.2A522 L523 A528 V529 A530 L608 D609 G610 S611A522-N526 WeakPolarHBondContact O-CB 3.25Å; A522-N526 PolarHBondContact O-N 3.3Å; L523-N526 PolarHBondContact O-N 2.84Å; N526-A528 VanDerWaalsContact C-N 3.3Å; N526-A528 PolarHBondContact O-N 3.43Å; N526-V529 PolarHBondContact O-N 2.98Å; N526-A530 PolarHBondContact O-N 2.95Å; N526-L608 HydrophobicContact CB-CB 4.2Å; N526-L608 HydrophobicContact CB-CD1 4.37Å; N526-L608 HydrophobicContact CB-CD2 4.35Å; N526-L608 WeakPolarHBondContact OD1-CB 3.43Å; N526-D609 PolarHBondContact OD1-N 3.2Å; N526-G610 WeakPolarHBondContact O-CA 3.39Å; N526-G610 WeakPolarHBondContact OD1-CA 3.46Å; N526-G610 PolarHBondContact OD1-N 2.95Å; N526-S611 PolarHBondContact ND2-O 3.08Å
527Q98.8Very high98.6Very high99 Ų9931.4 Ų31.446%0.46319%0.192SC..Hα-helixtrans-61.8-38.9173.6-170.362.652.500111.9L523 I525 V529 A530 D531L523-Q527 WeakPolarHBondContact O-CB 3.39Å; L523-Q527 PolarHBondContact O-N 3.42Å; I525-Q527 VanDerWaalsContact C-N 3.3Å; I525-Q527 PolarHBondContact O-N 3.39Å; Q527-V529 VanDerWaalsContact C-N 3.3Å; Q527-V529 PolarHBondContact O-N 3.26Å; Q527-A530 WeakPolarHBondContact O-CB 3.43Å; Q527-A530 PolarHBondContact O-N 3.43Å; Q527-D531 PolarHBondContact NE2-OD1 3Å; Q527-D531 WeakPolarHBondContact O-CB 3.42Å; Q527-D531 PolarHBondContact O-N 3.29Å
528A98.8Very high98.6Very high0 Ų031.4 Ų31.40%019%0.192CC..Hα-helixtrans-65-32.9177.100000113.6I467 A524 I525 N526 G532 R533 V534I467-A528 HydrophobicContact CD1-CB 3.5Å; A524-A528 WeakPolarHBondContact O-CB 3.49Å; A524-A528 PolarHBondContact O-N 2.85Å; I525-A528 WeakPolarHBondContact O-CA 3.27Å; I525-A528 WeakPolarHBondContact O-CB 3.37Å; I525-A528 PolarHBondContact O-N 3.36Å; N526-A528 VanDerWaalsContact C-N 3.3Å; N526-A528 PolarHBondContact O-N 3.43Å; A528-G532 PolarHBondContact O-N 3.38Å; A528-R533 VanDerWaalsContact CA-NH2 3.3Å; A528-R533 HydrophobicContact CB-CB 4.31Å; A528-R533 VanDerWaalsContact CB-NH1 3.27Å; A528-R533 PolarHBondContact O-N 2.88Å; A528-V534 HydrophobicContact CB-CB 4.36Å; A528-V534 HydrophobicContact CB-CG2 3.75Å; A528-V534 PolarHBondContact O-N 2.96Å
529V98.8Very high98.7Very high19 Ų1931.3 Ų31.312%0.11519%0.192CC..Hα-helixtrans-67.7-45.2170.6177.80000110.3I525 N526 Q527 D531 G532 V534 V538I525-V529 WeakPolarHBondContact O-CG2 3.29Å; I525-V529 PolarHBondContact O-N 3.17Å; N526-V529 PolarHBondContact O-N 2.98Å; Q527-V529 VanDerWaalsContact C-N 3.3Å; Q527-V529 PolarHBondContact O-N 3.26Å; V529-D531 VanDerWaalsContact C-N 3.33Å; V529-D531 PolarHBondContact O-N 3.12Å; V529-G532 PolarHBondContact O-N 3.08Å; V529-G532 VanDerWaalsContact O-N 3.16Å; V529-V534 HydrophobicContact CG2-CB 4.08Å; V529-V534 HydrophobicContact CG2-CG1 4.02Å; V529-V538 HydrophobicContact CG2-CG2 4.12Å
530A98.7Very high98.7Very high54 Ų5430.9 Ų30.945%0.44619%0.189SC..Hα-helixtrans-60.8-40.1178.400000112.9N526 Q527 G532 G610N526-A530 PolarHBondContact O-N 2.95Å; Q527-A530 WeakPolarHBondContact O-CB 3.43Å; Q527-A530 PolarHBondContact O-N 3.43Å; A530-G532 VanDerWaalsContact C-N 3.28Å; A530-G532 PolarHBondContact O-N 3.14Å; A530-G610 WeakPolarHBondContact CB-O 3.3Å
531D97.9Very high98.7Very high89 Ų8928.7 Ų28.748%0.47617%0.174SC..THydrogen-bonded Turntrans-79.2-7.7179.5-57.2-23.8000113.3Q527 V529 R533Q527-D531 PolarHBondContact NE2-OD1 3Å; Q527-D531 WeakPolarHBondContact O-CB 3.42Å; Q527-D531 PolarHBondContact O-N 3.29Å; V529-D531 VanDerWaalsContact C-N 3.33Å; V529-D531 PolarHBondContact O-N 3.12Å; D531-R533 VanDerWaalsContact C-N 3.28Å; D531-R533 HydrophobicContact CB-CG 4.34Å; D531-R533 PolarHBondContact O-N 3.31Å; D531-R533 IonicContact OD2-CZ 3.71Å; D531-R533 IonicContact OD2-NE 3.66Å; D531-R533 PolarHBondContact OD2-NE 3.28Å; D531-R533 IonicContact OD2-NH2 3.37Å; D531-R533 PolarHBondContact OD2-NH2 2.92Å
532G98.1Very high98.6Very high56 Ų5628.7 Ų28.758%0.57717%0.174SC*.THydrogen-bonded Turntrans73.111.9-174.900000115.2A528 V529 A530 V534A528-G532 PolarHBondContact O-N 3.38Å; V529-G532 PolarHBondContact O-N 3.08Å; V529-G532 VanDerWaalsContact O-N 3.16Å; A530-G532 VanDerWaalsContact C-N 3.28Å; A530-G532 PolarHBondContact O-N 3.14Å; G532-V534 VanDerWaalsContact C-N 3.29Å
533R98.4Very high98.5Very high119 Ų11930.1 Ų30.145%0.44918%0.182SC..SBendtrans-71.3-27.8172-70.9-178.5-72.2109.4-2.8112.1A528 D531A528-R533 VanDerWaalsContact CA-NH2 3.3Å; A528-R533 HydrophobicContact CB-CB 4.31Å; A528-R533 VanDerWaalsContact CB-NH1 3.27Å; A528-R533 PolarHBondContact O-N 2.88Å; D531-R533 VanDerWaalsContact C-N 3.28Å; D531-R533 HydrophobicContact CB-CG 4.34Å; D531-R533 PolarHBondContact O-N 3.31Å; D531-R533 IonicContact OD2-CZ 3.71Å; D531-R533 IonicContact OD2-NE 3.66Å; D531-R533 PolarHBondContact OD2-NE 3.28Å; D531-R533 IonicContact OD2-NH2 3.37Å; D531-R533 PolarHBondContact OD2-NH2 2.92Å
534V98.6Very high98.4Very high1 Ų128.4 Ų28.41%0.00617%0.173CC..SBendtrans-112.6124.7166.7175.60000106.7D460 V463 T464 A528 V529 G532 A536 V538D460-V534 HydrophobicContact CB-CG1 4.07Å; D460-V534 WeakPolarHBondContact OD1-CA 3.22Å; V463-V534 HydrophobicContact CB-CG2 4.38Å; V463-V534 HydrophobicContact CG1-CG2 3.83Å; T464-V534 HydrophobicContact CG2-CG2 3.94Å; A528-V534 HydrophobicContact CB-CB 4.36Å; A528-V534 HydrophobicContact CB-CG2 3.75Å; A528-V534 PolarHBondContact O-N 2.96Å; V529-V534 HydrophobicContact CG2-CB 4.08Å; V529-V534 HydrophobicContact CG2-CG1 4.02Å; G532-V534 VanDerWaalsContact C-N 3.29Å; V534-A536 VanDerWaalsContact C-N 3.34Å; V534-A536 WeakPolarHBondContact CG1-O 3.27Å; V534-A536 PolarHBondContact O-N 3.17Å; V534-V538 HydrophobicContact CG1-CG2 3.8Å
535S98.4Very high98.2Very high80 Ų8027.6 Ų27.656%0.55916%0.164SC*.SBendtrans-73.4-21.5-162.972.10000115.1S455 D460S455-S535 WeakPolarHBondContact CB-OG 3.25Å; D460-S535 PolarHBondContact OD1-N 2.81Å; D460-S535 PolarHBondContact OD1-OG 3.18Å; D460-S535 PolarHBondContact OD2-N 2.69Å; D460-S535 PolarHBondContact OD2-OG 2.84Å
536A98.6Very high98.1Very high7 Ų727.6 Ų27.66%0.05816%0.164CC..SBendtrans-142.9166.7-178.200000111.2I90 V534I90-A536 HydrophobicContact CG2-CB 4.27Å; V534-A536 VanDerWaalsContact C-N 3.34Å; V534-A536 WeakPolarHBondContact CG1-O 3.27Å; V534-A536 PolarHBondContact O-N 3.17Å
537P98.8Very high97.9Very high5 Ų527.2 Ų27.23%0.03216%0.162CC..  trans-50.7154.6173.5-30.237.8000113.9T454 L607 L608 D609T454-P537 VanDerWaalsContact CB-O 3.26Å; T454-P537 WeakPolarHBondContact CB-O 3.17Å; T454-P537 VanDerWaalsContact CG2-O 3.24Å; T454-P537 WeakPolarHBondContact CG2-O 3.26Å; T454-P537 PolarHBondContact N-O 2.75Å; T454-P537 VanDerWaalsContact N-O 3.11Å; T454-P537 PolarHBondContact OG1-O 3.34Å; P537-L607 HydrophobicContact CB-CD1 3.64Å; P537-L607 HydrophobicContact CB-CD2 4.46Å; P537-L607 HydrophobicContact CB-CG 4.14Å; P537-L608 CarbonylContact C-O 3.58Å; P537-L608 WeakPolarHBondContact CA-O 3.36Å; P537-L608 WeakPolarHBondContact CB-O 3.25Å; P537-D609 HydrophobicContact CB-CB 4.38Å; P537-D609 HydrophobicContact CG-CB 4.23Å
538V98.9Very high97.9Very high0 Ų022.5 Ų22.50%014%0.14CC..EExtended strand (participates in β ladder)trans-119.8130.1177.51770000109.4W451 V452 I525 V529 V534 I540 L608W451-V538 HydrophobicContact CB-CG1 3.74Å; W451-V538 HydrophobicContact CG-CG1 4.18Å; V452-V538 WeakPolarHBondContact O-CA 3.37Å; I525-V538 HydrophobicContact CG2-CB 3.69Å; I525-V538 HydrophobicContact CG2-CG1 3.88Å; I525-V538 HydrophobicContact CG2-CG2 3.72Å; V529-V538 HydrophobicContact CG2-CG2 4.12Å; V534-V538 HydrophobicContact CG1-CG2 3.8Å; V538-I540 HydrophobicContact CG1-CD1 4.17Å; V538-L608 PolarHBondContact N-O 3.05Å; V538-L608 WeakPolarHBondContact O-CB 3.27Å; V538-L608 PolarHBondContact O-N 3.5Å
539V98.9Very high97.8Very high0 Ų022.5 Ų22.50%014%0.14CC..EExtended strand (participates in β ladder)trans-86.7123.8171.5170.50000108.5A102 M106 W451 V452 T454 W585 L606 L607A102-V539 HydrophobicContact CB-CG2 3.81Å; M106-V539 HydrophobicContact CE-CG1 4.42Å; M106-V539 HydrophobicContact CG-CG1 4.46Å; M106-V539 HydrophobicContact CG-CG2 4.5Å; M106-V539 HydrophobicContact SD-CB 4.42Å; M106-V539 HydrophobicContact SD-CG1 4.25Å; W451-V539 CarbonylContact C-O 3.56Å; W451-V539 WeakPolarHBondContact CA-O 3.3Å; W451-V539 WeakPolarHBondContact CB-O 3.46Å; V452-V539 HydrophobicContact CB-CB 4.38Å; V452-V539 PolarHBondContact N-O 2.93Å; V452-V539 PolarHBondContact O-N 2.82Å; T454-V539 HydrophobicContact CG2-CG2 3.79Å; V539-W585 HydrophobicContact CG1-CH2 3.56Å; V539-W585 HydrophobicContact CG1-CZ2 4.37Å; V539-W585 HydrophobicContact CG1-CZ3 4.3Å; V539-L606 CarbonylContact C-O 3.6Å; V539-L606 WeakPolarHBondContact CA-O 3.03Å; V539-L607 HydrophobicContact CG2-CD1 3.78Å
540I98.5Very high97.8Very high0 Ų021.6 Ų21.60%014%0.135CC..EExtended strand (participates in β ladder)trans-93.8141.5165-55.6-56000109.3F449 R450 W451 I525 V538 F604 G605 L606 L608F449-I540 HydrophobicContact CD2-CG2 4.05Å; F449-I540 HydrophobicContact CE1-CD1 4.29Å; F449-I540 HydrophobicContact CE2-CG2 3.35Å; F449-I540 HydrophobicContact CZ-CD1 3.87Å; F449-I540 HydrophobicContact CZ-CG1 4.31Å; F449-I540 HydrophobicContact CZ-CG2 3.68Å; R450-I540 WeakPolarHBondContact O-CA 3.47Å; W451-I540 HydrophobicContact CB-CD1 3.49Å; W451-I540 VanDerWaalsContact CB-CD1 3.49Å; W451-I540 HydrophobicContact CG-CD1 4.49Å; I525-I540 HydrophobicContact CD1-CD1 4.33Å; V538-I540 HydrophobicContact CG1-CD1 4.17Å; I540-F604 HydrophobicContact CG2-CE2 4.23Å; I540-F604 HydrophobicContact CG2-CZ 4.37Å; I540-G605 CarbonylContact O-C 3.23Å; I540-G605 WeakPolarHBondContact O-CA 3.12Å; I540-L606 PolarHBondContact N-O 3.08Å; I540-L606 PolarHBondContact O-N 3.47Å; I540-L608 HydrophobicContact CD1-CD1 3.76Å; I540-L608 HydrophobicContact CG1-CD1 3.39Å; I540-L608 HydrophobicContact CG1-CD2 4.48Å; I540-L608 HydrophobicContact CG1-CG 3.78Å
541S98.4Very high97.8Very high1 Ų119.2 Ų19.21%0.00711%0.114CC..EExtended strand (participates in β ladder)trans-157.6-167.1174.6-177.70000109.5C211 R450 F604C211-S541 VanDerWaalsContact CB-OG 3.24Å; C211-S541 WeakPolarHBondContact CB-OG 3.37Å; C211-S541 PolarHBondContact SG-OG 3.36Å; C211-S541 VanDerWaalsContact SG-OG 3.4Å; R450-S541 VanDerWaalsContact CG-C 3.46Å; R450-S541 WeakPolarHBondContact CG-O 3.44Å; R450-S541 PolarHBondContact N-O 2.83Å; R450-S541 PolarHBondContact O-N 3.19Å; R450-S541 VanDerWaalsContact O-O 3.14Å; S541-F604 WeakPolarHBondContact CB-O 3.38Å; S541-F604 PolarHBondContact OG-O 2.68Å
542R97.6Very high97.7Very high1 Ų115 Ų150%0.0049%0.092CC..  trans-157.2168.1172.257.4169.8178.970.80.1111.7P448 D546 N574 G602 F604 D625P448-R542 HydrophobicContact CB-CB 4.27Å; P448-R542 HydrophobicContact CG-CB 4.18Å; P448-R542 WeakPolarHBondContact O-CB 3.22Å; R542-D546 WeakPolarHBondContact CD-OD2 3.49Å; R542-D546 IonicContact CZ-OD2 3.18Å; R542-D546 IonicContact NE-OD2 3.2Å; R542-D546 PolarHBondContact NE-OD2 3.39Å; R542-N574 PolarHBondContact NH2-ND2 3.45Å; R542-N574 VanDerWaalsContact NH2-ND2 3.19Å; R542-G602 PolarHBondContact NH1-O 3.09Å; R542-G602 PolarHBondContact NH2-O 3.22Å; R542-F604 HydrophobicContact CG-CD1 4.09Å; R542-F604 HydrophobicContact CG-CE1 3.63Å; R542-F604 HydrophobicContact CG-CZ 4.33Å; R542-D625 IonicContact CZ-OD1 3.27Å; R542-D625 IonicContact CZ-OD2 3.61Å; R542-D625 IonicContact NE-OD1 3.76Å; R542-D625 PolarHBondContact NE-OD1 3.08Å; R542-D625 IonicContact NE-OD2 2.75Å; R542-D625 PolarHBondContact NE-OD2 3.16Å; R542-D625 IonicContact NH2-OD1 3.54Å; R542-D625 PolarHBondContact NH2-OD1 3.23Å; R542-D625 IonicContact NH2-OD2 3.74Å
543D95.7Very high97.5Very high29 Ų2912.8 Ų12.816%0.1557%0.067CC..  trans-70161.4160.6-154.2-19.1000109.7M205 T206 P448 H545M205-D543 WeakPolarHBondContact CB-OD1 3.29Å; T206-D543 HydrophobicContact CG2-CB 4.16Å; T206-D543 WeakPolarHBondContact CG2-OD1 3.28Å; P448-D543 HydrophobicContact CB-CB 4.28Å; P448-D543 HydrophobicContact CG-CB 4.08Å; D543-H545 HydrophobicContact CB-CB 4.44Å; D543-H545 PolarHBondContact O-N 2.61Å
544H97.4Very high97.1Very high0 Ų08.5 Ų8.50%05%0.052CC..SBendtrans-76.9-16.1174.8-56.7-165.3000110.8M205 S209 D546 T550 H589 N601 G602M205-H544 HydrophobicContact CB-CB 3.75Å; M205-H544 HydrophobicContact CG-CB 3.77Å; M205-H544 PolarHBondContact O-CE1 2.96Å; M205-H544 PolarHBondContact O-NE2 3.39Å; M205-H544 HydrophobicContact SD-CB 4.04Å; S209-H544 PolarHBondContact OG-NE2 2.83Å; H544-D546 PolarHBondContact O-N 3.46Å; H544-T550 WeakPolarHBondContact O-CB 3.26Å; H544-T550 PolarHBondContact O-OG1 3.06Å; H544-H589 AromaticContact CE1-CE1 3.65Å; H544-H589 AromaticContact CE1-CG 3.88Å; H544-H589 AromaticContact CE1-ND1 3.48Å; H544-H589 PolarHBondContact CE1-ND1 3.01Å; H544-H589 AromaticContact ND1-ND1 3.98Å; H544-N601 HydrophobicContact CB-CB 3.92Å; H544-N601 PolarHBondContact ND1-ND2 3.04Å; H544-N601 PolarHBondContact ND1-O 3.27Å; H544-G602 WeakPolarHBondContact CB-O 3.45Å; H544-G602 VanDerWaalsContact CG-C 3.5Å; H544-G602 VanDerWaalsContact CG-O 3.3Å; H544-G602 PolarHBondContact ND1-N 3.22Å
545H94.9Very high96.8Very high12 Ų129.9 Ų9.96%0.0566%0.057CC..  trans-66.170.4170.4-175.456.9000112.1M205 Y433 F442 P448 Y512 D543 E556M205-H545 HydrophobicContact CE-CB 4.24Å; M205-H545 HydrophobicContact SD-CB 4.04Å; Y433-H545 AromaticContact CE2-NE2 3.67Å; Y433-H545 AromaticContact CZ-CE1 3.64Å; Y433-H545 AromaticContact CZ-NE2 3.6Å; Y433-H545 PolarHBondContact OH-CE1 3.29Å; Y433-H545 PolarHBondContact OH-ND1 3.09Å; Y433-H545 PolarHBondContact OH-NE2 3.46Å; F442-H545 AromaticContact CE2-CE1 3.5Å; F442-H545 AromaticContact CE2-NE2 3.86Å; F442-H545 AromaticContact CZ-CD2 3.76Å; F442-H545 AromaticContact CZ-CE1 3.41Å; F442-H545 VanDerWaalsContact CZ-CE1 3.41Å; F442-H545 WeakPolarHBondContact CZ-CE1 3.35Å; F442-H545 AromaticContact CZ-ND1 3.86Å; F442-H545 AromaticContact CZ-NE2 3.39Å; F442-H545 WeakPolarHBondContact CZ-NE2 3.45Å; P448-H545 WeakPolarHBondContact CD-O 3.29Å; P448-H545 WeakPolarHBondContact CG-O 3.39Å; Y512-H545 PolarHBondContact OH-CD2 2.86Å; Y512-H545 VanDerWaalsContact OH-CD2 3.32Å; D543-H545 HydrophobicContact CB-CB 4.44Å; D543-H545 PolarHBondContact O-N 2.61Å; H545-E556 IonicContact CE1-OE1 3.87Å; H545-E556 IonicContact CG-OE1 3.14Å; H545-E556 WeakPolarHBondContact ND1-CG 3.39Å; H545-E556 IonicContact ND1-OE1 3.59Å; H545-E556 PolarHBondContact ND1-OE1 3.3Å
546D95.9Very high96.6Very high0 Ų06.1 Ų6.10%03%0.03CC..SBendtrans-140.6170.4-172.9-165.621.4000112.1G447 P448 R518 R542 H544 S548G447-D546 WeakPolarHBondContact CA-OD1 3.3Å; P448-D546 HydrophobicContact CG-CB 4.04Å; R518-D546 IonicContact CZ-OD1 2.87Å; R518-D546 IonicContact CZ-OD2 2.92Å; R518-D546 IonicContact NH1-OD1 2.89Å; R518-D546 IonicContact NH1-OD2 2.7Å; R518-D546 PolarHBondContact NH1-OD2 2.88Å; R518-D546 IonicContact NH2-OD1 3.79Å; R518-D546 PolarHBondContact NH2-OD1 3.31Å; R518-D546 IonicContact NH2-OD2 3.36Å; R518-D546 PolarHBondContact NH2-OD2 3.38Å; R542-D546 WeakPolarHBondContact CD-OD2 3.49Å; R542-D546 IonicContact CZ-OD2 3.18Å; R542-D546 IonicContact NE-OD2 3.2Å; R542-D546 PolarHBondContact NE-OD2 3.39Å; H544-D546 PolarHBondContact O-N 3.46Å; D546-S548 VanDerWaalsContact C-N 3.32Å; D546-S548 PolarHBondContact O-N 2.9Å
547V96.3Very high96.3Very high0 Ų05.8 Ų5.80%03%0.028CC..THydrogen-bonded Turntrans-53.5-41.7-17656.70000114.2F442 V626 V630 R633F442-V547 HydrophobicContact CB-CB 4.23Å; F442-V547 HydrophobicContact CB-CG2 4.46Å; F442-V547 HydrophobicContact CD1-CB 4.44Å; F442-V547 WeakPolarHBondContact O-CG2 3.35Å; V547-V626 HydrophobicContact CG1-CG1 4.19Å; V547-V630 HydrophobicContact CG2-CG2 3.88Å; V547-R633 PolarHBondContact O-NE 3.13Å
548S97.9Very high96Very high0 Ų05.6 Ų5.60%03%0.026CC..THydrogen-bonded Turntrans-116.4-21.8-173-430000114.1D546 T550 N574 D625 V626 G629D546-S548 VanDerWaalsContact C-N 3.32Å; D546-S548 PolarHBondContact O-N 2.9Å; S548-T550 VanDerWaalsContact C-N 3.29Å; S548-T550 PolarHBondContact O-N 2.75Å; S548-N574 WeakPolarHBondContact CB-OD1 3.43Å; S548-D625 WeakPolarHBondContact CB-O 3.33Å; S548-D625 PolarHBondContact OG-O 3.48Å; S548-V626 PolarHBondContact OG-O 3.32Å; S548-G629 WeakPolarHBondContact OG-CA 3.43Å; S548-G629 PolarHBondContact OG-N 3.44Å
549G97.4Very high95.6Very high0 Ų06 Ų60%03%0.029CC..THydrogen-bonded Turntrans-71.4-21.1-168.100000114N601 G602G549-N601 CarbonylContact O-C 3.56Å; G549-N601 WeakPolarHBondContact O-CA 3.46Å; G549-G602 PolarHBondContact O-N 3.07Å
550T98.4Very high95.2Very high0 Ų06.4 Ų6.40%03%0.031CC..EExtended strand (participates in β ladder)trans-139.3130.5-166.6-62.50000113.3H544 S548 E556 M570 V599 I600 N601H544-T550 WeakPolarHBondContact O-CB 3.26Å; H544-T550 PolarHBondContact O-OG1 3.06Å; S548-T550 VanDerWaalsContact C-N 3.29Å; S548-T550 PolarHBondContact O-N 2.75Å; T550-E556 HydrophobicContact CG2-CB 3.9Å; T550-E556 HydrophobicContact CG2-CG 3.81Å; T550-E556 WeakPolarHBondContact CG2-OE2 3.28Å; T550-M570 WeakPolarHBondContact O-CE 3.31Å; T550-V599 HydrophobicContact CG2-CG1 3.44Å; T550-V599 VanDerWaalsContact CG2-CG1 3.44Å; T550-I600 WeakPolarHBondContact CA-O 3.37Å; T550-N601 HydrophobicContact CG2-CB 3.73Å; T550-N601 WeakPolarHBondContact OG1-CB 3.48Å
551D98.2Very high94.8Very high4 Ų412.8 Ų12.82%0.0216%0.056CC..EExtended strand (participates in β ladder)trans-100.7113.8162.9-72.6-63.3000109.1C567 A568 M570 A571 V599 I600 R632D551-C567 WeakPolarHBondContact CB-O 3.44Å; D551-A568 WeakPolarHBondContact OD2-CA 3.18Å; D551-M570 WeakPolarHBondContact OD2-CB 3.22Å; D551-M570 PolarHBondContact OD2-N 2.94Å; D551-A571 HydrophobicContact CB-CB 4.47Å; D551-A571 WeakPolarHBondContact OD2-CB 3.5Å; D551-A571 PolarHBondContact OD2-N 3.41Å; D551-V599 WeakPolarHBondContact O-CG1 3.48Å; D551-I600 PolarHBondContact N-O 2.84Å; D551-I600 PolarHBondContact O-N 3.05Å; D551-I600 VanDerWaalsContact O-N 3.09Å; D551-R632 IonicContact OD1-CZ 3.73Å; D551-R632 IonicContact OD1-NH1 3.76Å; D551-R632 PolarHBondContact OD1-NH1 3Å; D551-R632 IonicContact OD1-NH2 2.77Å
552S96.3Very high94.5Very high0 Ų016.1 Ų16.10%07%0.074CC..  trans-147.9104.2178.9-178.10000110.2F554 R555 E556 T557 V594 V599S552-F554 PolarHBondContact O-N 3.09Å; S552-R555 CarbonylContact O-C 3.57Å; S552-R555 PolarHBondContact O-N 2.93Å; S552-R555 PolarHBondContact OG-N 3.34Å; S552-E556 WeakPolarHBondContact CB-OE2 3.48Å; S552-E556 PolarHBondContact O-N 2.87Å; S552-T557 PolarHBondContact N-OG1 2.91Å; S552-T557 PolarHBondContact O-N 2.88Å; S552-T557 PolarHBondContact O-OG1 2.92Å; S552-V594 VanDerWaalsContact OG-CG2 3.31Å; S552-V594 WeakPolarHBondContact OG-CG2 3.37Å; S552-V599 WeakPolarHBondContact OG-CG2 3.15Å
553P93.1Very high94.3Very high10 Ų1018.8 Ų18.87%0.06510%0.101CC..THydrogen-bonded Turntrans-62.5-20-175.222.3-32.3000113.5T426 S558 A565 F566T426-P553 HydrophobicContact CG2-CB 3.88Å; P553-S558 VanDerWaalsContact O-CA 3.3Å; P553-S558 WeakPolarHBondContact O-CA 3.38Å; P553-S558 VanDerWaalsContact O-CB 3.24Å; P553-S558 WeakPolarHBondContact O-CB 3.47Å; P553-A565 HydrophobicContact CB-CB 4.18Å; P553-F566 HydrophobicContact CB-CD1 4.02Å; P553-F566 HydrophobicContact CB-CE1 3.96Å; P553-F566 HydrophobicContact CB-CG 4.42Å; P553-F566 HydrophobicContact CB-CZ 4.32Å; P553-F566 HydrophobicContact CG-CD1 3.84Å; P553-F566 HydrophobicContact CG-CE1 3.95Å
554F90.3Very high94.3Very high29 Ų2918.5 Ų18.513%0.12710%0.102CC..THydrogen-bonded Turntrans-100.8-4.2179.6-55.2-70.2000113.4L409 T426 F428 S552 V594 E598L409-F554 HydrophobicContact CD1-CE1 4.15Å; L409-F554 HydrophobicContact CD1-CZ 4.05Å; L409-F554 HydrophobicContact CD2-CD2 4.14Å; L409-F554 HydrophobicContact CD2-CE2 4.06Å; L409-F554 HydrophobicContact CD2-CG 4.49Å; L409-F554 HydrophobicContact CD2-CZ 4.35Å; T426-F554 HydrophobicContact CG2-CE1 4.31Å; F428-F554 HydrophobicContact CE2-CD1 4.06Å; F428-F554 HydrophobicContact CE2-CE1 4.39Å; F428-F554 HydrophobicContact CZ-CD1 4.42Å; F428-F554 HydrophobicContact CZ-CE1 4.35Å; S552-F554 PolarHBondContact O-N 3.09Å; F554-V594 HydrophobicContact CB-CG1 4.26Å; F554-V594 HydrophobicContact CB-CG2 4.27Å; F554-V594 HydrophobicContact CD2-CG1 4.37Å; F554-E598 WeakPolarHBondContact CE2-OE2 3.36Å
555R91.8Very high94.2Very high30 Ų3018.7 Ų18.711%0.11310%0.103CC..THydrogen-bonded Turntrans-142-98.5177.8-74-179.777152.9-5111.9G404 Y433 V434 S552 T557 S558 G593 V594G404-R555 VanDerWaalsContact CA-CD 3.49Å; G404-R555 WeakPolarHBondContact O-CD 3.17Å; G404-R555 PolarHBondContact O-NH1 3.26Å; Y433-R555 PolarHBondContact OH-NH2 3.12Å; V434-R555 WeakPolarHBondContact CB-O 3.28Å; V434-R555 WeakPolarHBondContact CG1-O 3.46Å; V434-R555 HydrophobicContact CG2-CB 4.4Å; S552-R555 CarbonylContact O-C 3.57Å; S552-R555 PolarHBondContact O-N 2.93Å; S552-R555 PolarHBondContact OG-N 3.34Å; R555-T557 PolarHBondContact O-N 3.37Å; R555-T557 VanDerWaalsContact O-N 3.09Å; R555-S558 WeakPolarHBondContact O-CB 3.19Å; R555-S558 PolarHBondContact O-N 3.07Å; R555-S558 PolarHBondContact O-OG 2.97Å; R555-G593 VanDerWaalsContact NH1-CA 3.33Å; R555-V594 HydrophobicContact CB-CG2 4.05Å; R555-V594 HydrophobicContact CG-CG2 3.45Å; R555-V594 VanDerWaalsContact CG-CG2 3.45Å
556E94.3Very high94.2Very high0 Ų024.1 Ų24.10%013%0.127CC..THydrogen-bonded Turntrans-58.8-32.4-163.7-70.971.6-150.900113.1H545 T550 S552 R633H545-E556 IonicContact CE1-OE1 3.87Å; H545-E556 IonicContact CG-OE1 3.14Å; H545-E556 WeakPolarHBondContact ND1-CG 3.39Å; H545-E556 IonicContact ND1-OE1 3.59Å; H545-E556 PolarHBondContact ND1-OE1 3.3Å; T550-E556 HydrophobicContact CG2-CB 3.9Å; T550-E556 HydrophobicContact CG2-CG 3.81Å; T550-E556 WeakPolarHBondContact CG2-OE2 3.28Å; S552-E556 WeakPolarHBondContact CB-OE2 3.48Å; S552-E556 PolarHBondContact O-N 2.87Å; E556-R633 PolarHBondContact O-NH1 3.1Å; E556-R633 PolarHBondContact O-NH2 3.18Å
557T94.1Very high94.2Very high0 Ų026.7 Ų26.70%014%0.144CC..THydrogen-bonded Turntrans-111.818.1178550000112.8S552 R555 N559 V560 A565 M570S552-T557 PolarHBondContact N-OG1 2.91Å; S552-T557 PolarHBondContact O-N 2.88Å; S552-T557 PolarHBondContact O-OG1 2.92Å; R555-T557 PolarHBondContact O-N 3.37Å; R555-T557 VanDerWaalsContact O-N 3.09Å; T557-N559 PolarHBondContact O-N 2.67Å; T557-V560 HydrophobicContact CG2-CG2 4.5Å; T557-V560 VanDerWaalsContact O-CB 3.27Å; T557-V560 WeakPolarHBondContact O-CB 3.3Å; T557-V560 PolarHBondContact O-N 3.46Å; T557-V560 VanDerWaalsContact O-N 3.07Å; T557-A565 PolarHBondContact OG1-O 2.97Å; T557-M570 HydrophobicContact CG2-CE 3.95Å
558S91.6Very high94.3Very high1 Ų128.3 Ų28.31%0.00716%0.158CC..THydrogen-bonded Turntrans-68.3-15.5179.661.20000114.5S432 Q435 P553 R555S432-S558 PolarHBondContact OG-OG 3.22Å; Q435-S558 WeakPolarHBondContact CG-O 3.33Å; Q435-S558 WeakPolarHBondContact CG-OG 3.49Å; Q435-S558 PolarHBondContact N-OG 3.39Å; Q435-S558 PolarHBondContact NE2-O 3.02Å; P553-S558 VanDerWaalsContact O-CA 3.3Å; P553-S558 WeakPolarHBondContact O-CA 3.38Å; P553-S558 VanDerWaalsContact O-CB 3.24Å; P553-S558 WeakPolarHBondContact O-CB 3.47Å; R555-S558 WeakPolarHBondContact O-CB 3.19Å; R555-S558 PolarHBondContact O-N 3.07Å; R555-S558 PolarHBondContact O-OG 2.97Å
559N89.8Confident94.4Very high9 Ų933.5 Ų33.55%0.04819%0.186CC..THydrogen-bonded Turntrans-97.720.4171.675.1-37.7000113.6G439 T557 Y561 R633G439-N559 VanDerWaalsContact CA-ND2 3.29Å; G439-N559 WeakPolarHBondContact CA-ND2 3.42Å; G439-N559 PolarHBondContact O-ND2 3.24Å; T557-N559 PolarHBondContact O-N 2.67Å; N559-Y561 HydrophobicContact CB-CE2 4.31Å; N559-Y561 WeakPolarHBondContact O-CD2 3.48Å; N559-Y561 VanDerWaalsContact O-CE2 3.28Å; N559-Y561 WeakPolarHBondContact O-CE2 3.4Å; N559-R633 PolarHBondContact OD1-NH1 3.28Å
560V91.3Very high94.4Very high8 Ų833.9 Ų33.95%0.04819%0.187CC..  trans-102.5116.2173.5168.30000108.3T557 D562 S564 A565T557-V560 HydrophobicContact CG2-CG2 4.5Å; T557-V560 VanDerWaalsContact O-CB 3.27Å; T557-V560 WeakPolarHBondContact O-CB 3.3Å; T557-V560 PolarHBondContact O-N 3.46Å; T557-V560 VanDerWaalsContact O-N 3.07Å; V560-D562 WeakPolarHBondContact CG1-OD1 3.41Å; V560-S564 VanDerWaalsContact CG1-OG 3.28Å; V560-S564 WeakPolarHBondContact CG1-OG 3.45Å; V560-A565 HydrophobicContact CB-CB 4.24Å; V560-A565 HydrophobicContact CG1-CB 4.32Å
561Y89.1Confident94.4Very high134 Ų13433.9 Ų33.953%0.52519%0.187SC..  trans-113.3-2.4-168.1-54.5-71.6000114.4N559 G563N559-Y561 HydrophobicContact CB-CE2 4.31Å; N559-Y561 WeakPolarHBondContact O-CD2 3.48Å; N559-Y561 VanDerWaalsContact O-CE2 3.28Å; N559-Y561 WeakPolarHBondContact O-CE2 3.4Å; Y561-G563 PolarHBondContact O-N 2.82Å; Y561-G563 VanDerWaalsContact O-N 3.12Å
562D93.3Very high94.5Very high72 Ų7236.6 Ų36.639%0.38520%0.204SC..SBendtrans-73.55.8176.870.2-14000113.8V560 S564 S636V560-D562 WeakPolarHBondContact CG1-OD1 3.41Å; D562-S564 VanDerWaalsContact C-N 3.32Å; D562-S564 VanDerWaalsContact CG-OG 3.3Å; D562-S564 WeakPolarHBondContact OD1-CB 3.49Å; D562-S564 PolarHBondContact OD1-N 2.92Å; D562-S564 PolarHBondContact OD1-OG 2.8Å; D562-S564 PolarHBondContact OD2-OG 3.36Å; D562-S636 VanDerWaalsContact CG-OG 3.3Å; D562-S636 PolarHBondContact OD1-OG 3.41Å; D562-S636 VanDerWaalsContact OD2-CA 3.29Å; D562-S636 WeakPolarHBondContact OD2-CA 3.06Å; D562-S636 WeakPolarHBondContact OD2-CB 3.47Å; D562-S636 PolarHBondContact OD2-OG 2.9Å
563G92.6Very high94.6Very high56 Ų5641.5 Ų41.558%0.57723%0.227SC*.SBendtrans87.4-11.4-174.600000114.5Y561 A565Y561-G563 PolarHBondContact O-N 2.82Å; Y561-G563 VanDerWaalsContact O-N 3.12Å; G563-A565 PolarHBondContact O-N 2.95Å
564S96.3Very high94.9Very high23 Ų2341 Ų4116%0.16122%0.224CC..G310 helixtrans-79-0.1-176.875.30000114.2V560 D562 F566 C567 R632 S636V560-S564 VanDerWaalsContact CG1-OG 3.28Å; V560-S564 WeakPolarHBondContact CG1-OG 3.45Å; D562-S564 VanDerWaalsContact C-N 3.32Å; D562-S564 VanDerWaalsContact CG-OG 3.3Å; D562-S564 WeakPolarHBondContact OD1-CB 3.49Å; D562-S564 PolarHBondContact OD1-N 2.92Å; D562-S564 PolarHBondContact OD1-OG 2.8Å; D562-S564 PolarHBondContact OD2-OG 3.36Å; S564-F566 PolarHBondContact O-N 2.97Å; S564-C567 VanDerWaalsContact O-CB 3.27Å; S564-C567 WeakPolarHBondContact O-CB 3.24Å; S564-C567 PolarHBondContact O-N 3.47Å; S564-R632 PolarHBondContact O-NH2 3.34Å; S564-R632 PolarHBondContact OG-NH2 3.26Å; S564-S636 PolarHBondContact OG-OG 3Å
565A94.4Very high95.3Very high4 Ų440.9 Ų40.93%0.03322%0.223CC..G310 helixtrans-57.8-24.3-17900000113.8P553 T557 V560 G563P553-A565 HydrophobicContact CB-CB 4.18Å; T557-A565 PolarHBondContact OG1-O 2.97Å; V560-A565 HydrophobicContact CB-CB 4.24Å; V560-A565 HydrophobicContact CG1-CB 4.32Å; G563-A565 PolarHBondContact O-N 2.95Å
566F94.9Very high95.6Very high127 Ų12742.6 Ų42.656%0.55724%0.237SC*.G310 helixtrans-90.2-7.3176.7-66.2-82.8000114.2A425 T426 P553 S564A425-F566 HydrophobicContact CB-CZ 4.29Å; T426-F566 HydrophobicContact CG2-CE1 4.2Å; T426-F566 HydrophobicContact CG2-CE2 3.7Å; T426-F566 HydrophobicContact CG2-CZ 3.36Å; P553-F566 HydrophobicContact CB-CD1 4.02Å; P553-F566 HydrophobicContact CB-CE1 3.96Å; P553-F566 HydrophobicContact CB-CG 4.42Å; P553-F566 HydrophobicContact CB-CZ 4.32Å; P553-F566 HydrophobicContact CG-CD1 3.84Å; P553-F566 HydrophobicContact CG-CE1 3.95Å; S564-F566 PolarHBondContact O-N 2.97Å
567C97.6Very high95.8Very high54 Ų5442.6 Ų42.637%0.36524%0.237SC..  trans-76.3154.7174.2-60.40000110.3D551 S564 D569D551-C567 WeakPolarHBondContact CB-O 3.44Å; S564-C567 VanDerWaalsContact O-CB 3.27Å; S564-C567 WeakPolarHBondContact O-CB 3.24Å; S564-C567 PolarHBondContact O-N 3.47Å; C567-D569 WeakPolarHBondContact CB-OD2 3Å
568A98.4Very high96Very high34 Ų3442.6 Ų42.628%0.28124%0.237SC..  trans-117.411.2179.800000113.3D551 M570 V572 I600D551-A568 WeakPolarHBondContact OD2-CA 3.18Å; A568-M570 VanDerWaalsContact C-N 3.34Å; A568-M570 PolarHBondContact O-N 2.78Å; A568-V572 WeakPolarHBondContact O-CG2 3.49Å; A568-V572 PolarHBondContact O-N 3.26Å; A568-I600 HydrophobicContact CB-CB 3.98Å; A568-I600 HydrophobicContact CB-CG1 3.77Å; A568-I600 HydrophobicContact CB-CG2 4.42Å
569D98.6Very high96.3Very high109 Ų10943.4 Ų43.458%0.58324%0.244SC*.Hα-helixtrans-62.1-40.3-174.3-61.9-85.3000112.2C567 V572 Q573C567-D569 WeakPolarHBondContact CB-OD2 3Å; D569-V572 PolarHBondContact O-N 3.11Å; D569-Q573 VanDerWaalsContact O-CB 3.24Å; D569-Q573 WeakPolarHBondContact O-CB 3.43Å; D569-Q573 WeakPolarHBondContact O-CG 3.46Å; D569-Q573 PolarHBondContact O-N 3.39Å
570M98.7Very high96.7Very high7 Ų749.5 Ų49.53%0.03427%0.27CS..Hα-helixtrans-64.3-47.8-175.2-176.1-174.370.500111.1T550 D551 T557 A568 Q573 N574 N628 R632T550-M570 WeakPolarHBondContact O-CE 3.31Å; D551-M570 WeakPolarHBondContact OD2-CB 3.22Å; D551-M570 PolarHBondContact OD2-N 2.94Å; T557-M570 HydrophobicContact CG2-CE 3.95Å; A568-M570 VanDerWaalsContact C-N 3.34Å; A568-M570 PolarHBondContact O-N 2.78Å; M570-Q573 PolarHBondContact O-N 2.79Å; M570-N574 WeakPolarHBondContact O-CB 3.5Å; M570-N574 PolarHBondContact O-N 3.5Å; M570-N628 PolarHBondContact O-ND2 3.19Å; M570-R632 HydrophobicContact CB-CG 4.29Å; M570-R632 HydrophobicContact CG-CB 4.25Å; M570-R632 HydrophobicContact CG-CG 4.29Å; M570-R632 HydrophobicContact SD-CB 3.93Å; M570-R632 HydrophobicContact SD-CG 3.95Å
571A98.6Very high97Very high0 Ų052.3 Ų52.30%028%0.28CS..Hα-helixtrans-64.2-42179.100000112.2D551 N574 F575 I600D551-A571 HydrophobicContact CB-CB 4.47Å; D551-A571 WeakPolarHBondContact OD2-CB 3.5Å; D551-A571 PolarHBondContact OD2-N 3.41Å; A571-N574 PolarHBondContact O-N 3.18Å; A571-F575 PolarHBondContact O-N 3.4Å; A571-F575 VanDerWaalsContact O-N 3.08Å; A571-I600 HydrophobicContact CB-CB 4.39Å; A571-I600 HydrophobicContact CB-CG2 3.92Å; A571-I600 VanDerWaalsContact CB-O 3.3Å; A571-I600 WeakPolarHBondContact CB-O 3.25Å
572V98.8Very high97.2Very high61 Ų6146.2 Ų46.237%0.3726%0.257SS..Hα-helixtrans-65.1-47.9176.3173.80000110.8A568 D569 N574 F575 V576 L588 I600A568-V572 WeakPolarHBondContact O-CG2 3.49Å; A568-V572 PolarHBondContact O-N 3.26Å; D569-V572 PolarHBondContact O-N 3.11Å; V572-N574 VanDerWaalsContact C-N 3.28Å; V572-N574 PolarHBondContact O-N 3.41Å; V572-F575 PolarHBondContact O-N 3.03Å; V572-V576 WeakPolarHBondContact O-CG2 3.37Å; V572-V576 PolarHBondContact O-N 2.89Å; V572-L588 HydrophobicContact CG2-CD2 4.23Å; V572-I600 HydrophobicContact CG2-CG2 4.5Å
573Q98.8Very high97.5Very high103 Ų10342.8 Ų42.848%0.48124%0.239SC..Hα-helixtrans-61.7-38.3177.9-71.5-69.5-600111.3D569 M570 V576 G577 W624D569-Q573 VanDerWaalsContact O-CB 3.24Å; D569-Q573 WeakPolarHBondContact O-CB 3.43Å; D569-Q573 WeakPolarHBondContact O-CG 3.46Å; D569-Q573 PolarHBondContact O-N 3.39Å; M570-Q573 PolarHBondContact O-N 2.79Å; Q573-V576 PolarHBondContact O-N 3.47Å; Q573-G577 WeakPolarHBondContact O-CA 3.44Å; Q573-G577 PolarHBondContact O-N 2.71Å; Q573-W624 HydrophobicContact CB-CZ2 4.36Å; Q573-W624 WeakPolarHBondContact O-CZ2 3.29Å
574N98.8Very high97.8Very high0 Ų040.1 Ų40.10%021%0.212CC..Hα-helixtrans-61.5-50.8176.8-155.380.1000111.3R542 S548 M570 A571 V572 V576 G577 D578 W624 D625 N628R542-N574 PolarHBondContact NH2-ND2 3.45Å; R542-N574 VanDerWaalsContact NH2-ND2 3.19Å; S548-N574 WeakPolarHBondContact CB-OD1 3.43Å; M570-N574 WeakPolarHBondContact O-CB 3.5Å; M570-N574 PolarHBondContact O-N 3.5Å; A571-N574 PolarHBondContact O-N 3.18Å; V572-N574 VanDerWaalsContact C-N 3.28Å; V572-N574 PolarHBondContact O-N 3.41Å; N574-V576 PolarHBondContact O-N 2.77Å; N574-G577 PolarHBondContact O-N 2.93Å; N574-D578 PolarHBondContact ND2-OD2 3.29Å; N574-D578 WeakPolarHBondContact O-CB 3.47Å; N574-D578 VanDerWaalsContact O-CG 3.3Å; N574-D578 PolarHBondContact O-N 2.94Å; N574-W624 PolarHBondContact O-NE1 3.05Å; N574-D625 PolarHBondContact ND2-OD1 3.31Å; N574-N628 WeakPolarHBondContact CB-ND2 3.42Å; N574-N628 PolarHBondContact OD1-ND2 3.08Å
575F98.8Very high97.9Very high27 Ų2739 Ų3912%0.11820%0.204CC..Hα-helixtrans-55.8-47.7178.3165.8-103.7000112.5I175 A571 V572 A579 V586 A587 L588I175-F575 HydrophobicContact CG2-CE2 4.18Å; I175-F575 HydrophobicContact CG2-CZ 3.57Å; A571-F575 PolarHBondContact O-N 3.4Å; A571-F575 VanDerWaalsContact O-N 3.08Å; V572-F575 PolarHBondContact O-N 3.03Å; F575-A579 PolarHBondContact O-N 3.24Å; F575-V586 HydrophobicContact CD2-CB 3.81Å; F575-V586 HydrophobicContact CD2-CG2 3.93Å; F575-V586 HydrophobicContact CE2-CB 3.82Å; F575-V586 HydrophobicContact CE2-CG2 3.49Å; F575-V586 VanDerWaalsContact CE2-CG2 3.49Å; F575-V586 HydrophobicContact CZ-CG2 4.16Å; F575-A587 VanDerWaalsContact CD2-C 3.46Å; F575-L588 HydrophobicContact CB-CB 4.31Å; F575-L588 HydrophobicContact CB-CD1 4.13Å; F575-L588 HydrophobicContact CD1-CB 4.14Å; F575-L588 HydrophobicContact CD1-CD2 4.24Å; F575-L588 HydrophobicContact CD2-CB 3.75Å; F575-L588 HydrophobicContact CE1-CB 4.36Å; F575-L588 HydrophobicContact CE2-CB 3.97Å; F575-L588 HydrophobicContact CG-CB 3.81Å; F575-L588 HydrophobicContact CZ-CB 4.26Å
576V98.7Very high98.1Very high65 Ų6538.9 Ų38.939%0.39420%0.203SC..Hα-helixtrans-67.3-44.5178.2-178.70000110.3V572 Q573 N574 D578 A579 F580V572-V576 WeakPolarHBondContact O-CG2 3.37Å; V572-V576 PolarHBondContact O-N 2.89Å; Q573-V576 PolarHBondContact O-N 3.47Å; N574-V576 PolarHBondContact O-N 2.77Å; V576-D578 PolarHBondContact O-N 3.45Å; V576-A579 WeakPolarHBondContact O-CB 3.24Å; V576-A579 PolarHBondContact O-N 2.94Å; V576-A579 VanDerWaalsContact O-N 3.16Å; V576-F580 HydrophobicContact CG1-CD1 4.18Å; V576-F580 HydrophobicContact CG1-CE1 3.97Å; V576-F580 WeakPolarHBondContact O-CD1 3.39Å; V576-F580 WeakPolarHBondContact O-CE1 3.32Å; V576-F580 PolarHBondContact O-N 3.11Å
577G98.7Very high98.3Very high1 Ų132.8 Ų32.81%0.0118%0.176CC..Hα-helixtrans-66.9-33.6-176.800000114.8Q573 N574 F580 R581 W624Q573-G577 WeakPolarHBondContact O-CA 3.44Å; Q573-G577 PolarHBondContact O-N 2.71Å; N574-G577 PolarHBondContact O-N 2.93Å; G577-F580 VanDerWaalsContact CA-CE1 3.49Å; G577-R581 VanDerWaalsContact CA-NH1 3.29Å; G577-R581 WeakPolarHBondContact O-CB 3.43Å; G577-R581 WeakPolarHBondContact O-CD 3.31Å; G577-R581 WeakPolarHBondContact O-CG 3.32Å; G577-R581 PolarHBondContact O-NH1 3.12Å; G577-W624 VanDerWaalsContact C-CD1 3.47Å; G577-W624 VanDerWaalsContact CA-NE1 3.3Å
578D98.8Very high98.4Very high0 Ų031 Ų310%016%0.163CC..Hα-helixtrans-67.1-39.4171.4-71.9-25.7000111N574 V576 F580 R581 A583 V586 M621N574-D578 PolarHBondContact ND2-OD2 3.29Å; N574-D578 WeakPolarHBondContact O-CB 3.47Å; N574-D578 VanDerWaalsContact O-CG 3.3Å; N574-D578 PolarHBondContact O-N 2.94Å; V576-D578 PolarHBondContact O-N 3.45Å; D578-F580 VanDerWaalsContact C-N 3.32Å; D578-F580 PolarHBondContact O-N 3.43Å; D578-R581 PolarHBondContact O-N 3.33Å; D578-R581 VanDerWaalsContact O-N 3.11Å; D578-A583 HydrophobicContact CB-CB 4.37Å; D578-A583 WeakPolarHBondContact O-CB 3.2Å; D578-A583 PolarHBondContact O-N 3.38Å; D578-V586 HydrophobicContact CB-CG1 3.78Å; D578-M621 HydrophobicContact CB-CG 4.26Å
579A98.4Very high98.4Very high18 Ų1829.3 Ų29.315%0.14915%0.149CC..Hα-helixtrans-60.1-39.6-17500000112.4P172 F575 V576 V586P172-A579 WeakPolarHBondContact CD-O 3.41Å; P172-A579 HydrophobicContact CG-CB 4.02Å; P172-A579 VanDerWaalsContact CG-O 3.29Å; P172-A579 WeakPolarHBondContact CG-O 3.35Å; F575-A579 PolarHBondContact O-N 3.24Å; V576-A579 WeakPolarHBondContact O-CB 3.24Å; V576-A579 PolarHBondContact O-N 2.94Å; V576-A579 VanDerWaalsContact O-N 3.16Å; A579-V586 HydrophobicContact CB-CG1 4.16Å; A579-V586 HydrophobicContact CB-CG2 3.94Å
580F97.3Very high98.4Very high137 Ų13724.4 Ų24.460%0.60112%0.123SC*.THydrogen-bonded Turntrans-95.97.5179.365.1-105.9000114.2V576 G577 D578V576-F580 HydrophobicContact CG1-CD1 4.18Å; V576-F580 HydrophobicContact CG1-CE1 3.97Å; V576-F580 WeakPolarHBondContact O-CD1 3.39Å; V576-F580 WeakPolarHBondContact O-CE1 3.32Å; V576-F580 PolarHBondContact O-N 3.11Å; G577-F580 VanDerWaalsContact CA-CE1 3.49Å; D578-F580 VanDerWaalsContact C-N 3.32Å; D578-F580 PolarHBondContact O-N 3.43Å
581R98.1Very high98.2Very high67 Ų6724 Ų2425%0.25312%0.121SC..THydrogen-bonded Turntrans-110.610.1176.8-72.1-178.1177.387.8-3.8114.1G577 D578 M621G577-R581 VanDerWaalsContact CA-NH1 3.29Å; G577-R581 WeakPolarHBondContact O-CB 3.43Å; G577-R581 WeakPolarHBondContact O-CD 3.31Å; G577-R581 WeakPolarHBondContact O-CG 3.32Å; G577-R581 PolarHBondContact O-NH1 3.12Å; D578-R581 PolarHBondContact O-N 3.33Å; D578-R581 VanDerWaalsContact O-N 3.11Å; R581-M621 HydrophobicContact CB-CB 4.15Å
582G93.3Very high98Very high5 Ų524 Ų245%0.05212%0.121CC..THydrogen-bonded Turntrans102.515.5167.600000115.5L606 R617G582-L606 WeakPolarHBondContact O-CD1 3.24Å; G582-R617 WeakPolarHBondContact O-CD 3.4Å
583A98.5Very high97.6Very high1 Ų121.4 Ų21.41%0.00811%0.106CC..  trans-52.3139.8166.300000110.6P172 D578 V586 F604 M621P172-A583 WeakPolarHBondContact CA-O 3.27Å; D578-A583 HydrophobicContact CB-CB 4.37Å; D578-A583 WeakPolarHBondContact O-CB 3.2Å; D578-A583 PolarHBondContact O-N 3.38Å; A583-V586 HydrophobicContact CB-CG1 3.6Å; A583-F604 HydrophobicContact CB-CB 4.35Å; A583-M621 HydrophobicContact CB-CG 4.38Å; A583-M621 HydrophobicContact CB-SD 3.69Å
584T98.8Very high97.1Very high0 Ų016.6 Ų16.60%08%0.084CC..SBendtrans-74.1-34.8174.5-57.70000111.3Q99 P172 R173 G605 L607Q99-T584 HydrophobicContact CB-CG2 3.59Å; Q99-T584 HydrophobicContact CG-CG2 3.7Å; Q99-T584 PolarHBondContact NE2-OG1 3.11Å; P172-T584 CarbonylContact C-O 3.5Å; P172-T584 WeakPolarHBondContact CA-O 3.28Å; R173-T584 HydrophobicContact CG-CG2 4.4Å; R173-T584 PolarHBondContact N-O 3.46Å; T584-G605 WeakPolarHBondContact CA-O 3.35Å; T584-G605 WeakPolarHBondContact CB-O 3.24Å; T584-G605 PolarHBondContact N-O 3.26Å; T584-L607 HydrophobicContact CG2-CB 4.47Å; T584-L607 PolarHBondContact OG1-N 3.15Å
585W98.9Very high96.7Very high0 Ų016.7 Ų16.70%09%0.085CC..EExtended strand (participates in β ladder)trans-148.2158.5163.267.396.8000110.5M103 M106 A174 S209 V539 F604 G605M103-W585 HydrophobicContact CG-CD2 4.02Å; M103-W585 HydrophobicContact CG-CE3 3.47Å; M103-W585 VanDerWaalsContact CG-CE3 3.47Å; M103-W585 HydrophobicContact CG-CH2 4.43Å; M103-W585 HydrophobicContact CG-CZ3 3.72Å; M103-W585 HydrophobicContact SD-CB 3.93Å; M103-W585 HydrophobicContact SD-CD2 4.19Å; M103-W585 HydrophobicContact SD-CE3 3.93Å; M103-W585 HydrophobicContact SD-CG 4.24Å; M106-W585 HydrophobicContact CG-CH2 4.08Å; M106-W585 HydrophobicContact CG-CZ2 4.47Å; A174-W585 HydrophobicContact CB-CB 3.99Å; A174-W585 VanDerWaalsContact O-CA 3.27Å; A174-W585 WeakPolarHBondContact O-CA 3.27Å; A174-W585 WeakPolarHBondContact O-CB 3.37Å; S209-W585 PolarHBondContact O-NE1 3.47Å; V539-W585 HydrophobicContact CG1-CH2 3.56Å; V539-W585 HydrophobicContact CG1-CZ2 4.37Å; V539-W585 HydrophobicContact CG1-CZ3 4.3Å; W585-F604 CarbonylContact O-C 3.53Å; W585-F604 VanDerWaalsContact O-CA 3.32Å; W585-F604 WeakPolarHBondContact O-CA 3.42Å; W585-G605 VanDerWaalsContact CE2-CA 3.49Å; W585-G605 PolarHBondContact N-O 3.43Å; W585-G605 PolarHBondContact O-N 3.43Å
586V98.9Very high96.5Very high0 Ų016 Ų160%08%0.081CC..EExtended strand (participates in β ladder)trans-130.4151.6176.2-68.30000110.6P172 A174 I175 I176 F575 D578 A579 A583P172-V586 HydrophobicContact CG-CG2 4.39Å; A174-V586 PolarHBondContact O-N 3.34Å; I175-V586 HydrophobicContact CB-CG2 4.48Å; I175-V586 HydrophobicContact CG1-CG2 4.15Å; I175-V586 HydrophobicContact CG2-CG2 4.29Å; I176-V586 WeakPolarHBondContact CB-O 3.21Å; I176-V586 PolarHBondContact N-O 3.01Å; F575-V586 HydrophobicContact CD2-CB 3.81Å; F575-V586 HydrophobicContact CD2-CG2 3.93Å; F575-V586 HydrophobicContact CE2-CB 3.82Å; F575-V586 HydrophobicContact CE2-CG2 3.49Å; F575-V586 VanDerWaalsContact CE2-CG2 3.49Å; F575-V586 HydrophobicContact CZ-CG2 4.16Å; D578-V586 HydrophobicContact CB-CG1 3.78Å; A579-V586 HydrophobicContact CB-CG1 4.16Å; A579-V586 HydrophobicContact CB-CG2 3.94Å; A583-V586 HydrophobicContact CB-CG1 3.6Å
587A98.9Very high96.3Very high0 Ų014.7 Ų14.70%08%0.081CC..EExtended strand (participates in β ladder)trans-137.6138.8179.600000112.3I176 S209 F575 G602 G603I176-A587 HydrophobicContact CB-CB 3.96Å; I176-A587 HydrophobicContact CD1-CB 4.46Å; I176-A587 HydrophobicContact CG2-CB 4.37Å; I176-A587 CarbonylContact O-C 3.21Å; I176-A587 VanDerWaalsContact O-CA 3.26Å; I176-A587 WeakPolarHBondContact O-CA 3.33Å; S209-A587 VanDerWaalsContact CB-CB 3.42Å; F575-A587 VanDerWaalsContact CD2-C 3.46Å; A587-G602 CarbonylContact O-C 3.21Å; A587-G602 WeakPolarHBondContact O-CA 3.43Å; A587-G603 PolarHBondContact N-O 2.86Å; A587-G603 PolarHBondContact O-N 2.89Å
588L98.9Very high96.1Very high15 Ų1517 Ų178%0.0799%0.092CC..EExtended strand (participates in β ladder)trans-126.9120.7169.7-172.167.8000110.1I176 T177 N178 M180 V572 F575 I600I176-L588 PolarHBondContact O-N 2.76Å; T177-L588 VanDerWaalsContact CA-O 3.3Å; T177-L588 WeakPolarHBondContact CA-O 3.28Å; N178-L588 PolarHBondContact N-O 3.24Å; M180-L588 HydrophobicContact CE-CG 4.25Å; M180-L588 HydrophobicContact SD-CD2 3.86Å; M180-L588 HydrophobicContact SD-CG 4.03Å; V572-L588 HydrophobicContact CG2-CD2 4.23Å; F575-L588 HydrophobicContact CB-CB 4.31Å; F575-L588 HydrophobicContact CB-CD1 4.13Å; F575-L588 HydrophobicContact CD1-CB 4.14Å; F575-L588 HydrophobicContact CD1-CD2 4.24Å; F575-L588 HydrophobicContact CD2-CB 3.75Å; F575-L588 HydrophobicContact CE1-CB 4.36Å; F575-L588 HydrophobicContact CE2-CB 3.97Å; F575-L588 HydrophobicContact CG-CB 3.81Å; F575-L588 HydrophobicContact CZ-CB 4.26Å; L588-I600 HydrophobicContact CD1-CG2 3.7Å; L588-I600 HydrophobicContact CG-CG2 4.29Å
589H98.8Very high96Very high0 Ų017.2 Ų17.20%09%0.093CC..EExtended strand (participates in β ladder)trans-120.6155.9-173.4-61.8178.3000111.8N178 M180 Q204 M205 S209 H544 N601N178-H589 PolarHBondContact ND2-CD2 2.86Å; N178-H589 PolarHBondContact ND2-NE2 3.24Å; N178-H589 CarbonylContact O-C 3.39Å; N178-H589 VanDerWaalsContact O-CA 3.28Å; N178-H589 WeakPolarHBondContact O-CA 3.35Å; M180-H589 WeakPolarHBondContact CE-O 2.97Å; Q204-H589 WeakPolarHBondContact O-CB 3.48Å; Q204-H589 PolarHBondContact O-ND1 2.96Å; M205-H589 PolarHBondContact O-CE1 3.25Å; M205-H589 PolarHBondContact O-ND1 3.36Å; M205-H589 VanDerWaalsContact O-ND1 3.16Å; S209-H589 PolarHBondContact N-CE1 2.8Å; H544-H589 AromaticContact CE1-CE1 3.65Å; H544-H589 AromaticContact CE1-CG 3.88Å; H544-H589 AromaticContact CE1-ND1 3.48Å; H544-H589 PolarHBondContact CE1-ND1 3.01Å; H544-H589 AromaticContact ND1-ND1 3.98Å; H589-N601 WeakPolarHBondContact CA-O 3.24Å; H589-N601 WeakPolarHBondContact CB-O 3.17Å; H589-N601 PolarHBondContact N-O 3.03Å; H589-N601 PolarHBondContact O-N 3.39Å; H589-N601 PolarHBondContact O-OD1 2.84Å; H589-N601 VanDerWaalsContact O-OD1 3.13Å
590N98.4Very high96.1Very high5 Ų518.2 Ų18.23%0.02710%0.096CC..EExtended strand (participates in β ladder)trans-106.3124.5171.51781.3000109.7N178 G179 M180 S186 Y202 G597 V599 I600N178-N590 PolarHBondContact O-N 2.73Å; G179-N590 WeakPolarHBondContact O-CB 3.5Å; G179-N590 PolarHBondContact O-ND2 3.35Å; M180-N590 HydrophobicContact CE-CB 3.62Å; S186-N590 PolarHBondContact OG-ND2 3.4Å; Y202-N590 WeakPolarHBondContact CD2-O 3.15Å; Y202-N590 WeakPolarHBondContact CE2-O 3.4Å; N590-G597 WeakPolarHBondContact OD1-CA 3.13Å; N590-G597 PolarHBondContact OD1-N 2.97Å; N590-V599 WeakPolarHBondContact CA-O 3.5Å; N590-V599 PolarHBondContact OD1-O 2.9Å; N590-I600 HydrophobicContact CB-CD1 4.44Å
591G95.6Very high96.1Very high0 Ų011.7 Ų11.70%07%0.067CC..SBendtrans91.66.5164.800000116.6Y202 G593 G595 V599Y202-G591 WeakPolarHBondContact CE2-O 3.47Å; Y202-G591 PolarHBondContact OH-O 2.91Å; G591-G593 PolarHBondContact O-N 2.94Å; G591-G595 CarbonylContact C-O 3.56Å; G591-G595 VanDerWaalsContact CA-C 3.5Å; G591-G595 WeakPolarHBondContact CA-O 3.24Å; G591-G595 CarbonylContact O-C 3.54Å; G591-G595 VanDerWaalsContact O-CA 3.24Å; G591-G595 WeakPolarHBondContact O-CA 3.42Å; G591-G595 PolarHBondContact O-N 2.61Å; G591-V599 PolarHBondContact N-O 3.5Å
592G94.4Very high96.1Very high0 Ų08.5 Ų8.50%06%0.055CC..THydrogen-bonded Turntrans-56.2133.3-177.800000112.3V594 V599 N601G592-V594 PolarHBondContact O-N 2.88Å; G592-V599 WeakPolarHBondContact O-CG1 3.31Å; G592-N601 WeakPolarHBondContact CA-OD1 3.3Å; G592-N601 PolarHBondContact N-OD1 3.18Å
593G89Confident96.4Very high5 Ų58.3 Ų8.35%0.0525%0.053CC..THydrogen-bonded Turntrans86.9-86.3-176.900000112.5R555 G591R555-G593 VanDerWaalsContact NH1-CA 3.33Å; G591-G593 PolarHBondContact O-N 2.94Å
594V89.2Confident96.4Very high3 Ų38.4 Ų8.42%0.0185%0.053CC..THydrogen-bonded Turntrans-70.5-32.4-171.6-174.40000113H347 A406 L409 S552 F554 R555 G592 E598 V599H347-V594 WeakPolarHBondContact CA-O 3.49Å; H347-V594 WeakPolarHBondContact CB-O 3.16Å; A406-V594 HydrophobicContact CB-CG1 3.88Å; L409-V594 HydrophobicContact CD2-CG1 4.48Å; S552-V594 VanDerWaalsContact OG-CG2 3.31Å; S552-V594 WeakPolarHBondContact OG-CG2 3.37Å; F554-V594 HydrophobicContact CB-CG1 4.26Å; F554-V594 HydrophobicContact CB-CG2 4.27Å; F554-V594 HydrophobicContact CD2-CG1 4.37Å; R555-V594 HydrophobicContact CB-CG2 4.05Å; R555-V594 HydrophobicContact CG-CG2 3.45Å; R555-V594 VanDerWaalsContact CG-CG2 3.45Å; G592-V594 PolarHBondContact O-N 2.88Å; V594-E598 HydrophobicContact CB-CB 4.17Å; V594-E598 HydrophobicContact CG1-CB 3.91Å; V594-E598 HydrophobicContact CG1-CG 4.23Å; V594-V599 HydrophobicContact CB-CG2 3.69Å; V594-V599 HydrophobicContact CG2-CG2 3.87Å
595G90.5Very high96.4Very high2 Ų28.4 Ų8.42%0.0215%0.053CC..  trans131163.7-178.300000113.5G591 G597 E598G591-G595 CarbonylContact C-O 3.56Å; G591-G595 VanDerWaalsContact CA-C 3.5Å; G591-G595 WeakPolarHBondContact CA-O 3.24Å; G591-G595 CarbonylContact O-C 3.54Å; G591-G595 VanDerWaalsContact O-CA 3.24Å; G591-G595 WeakPolarHBondContact O-CA 3.42Å; G591-G595 PolarHBondContact O-N 2.61Å; G595-G597 PolarHBondContact O-N 3.45Å; G595-E598 WeakPolarHBondContact O-CB 3.3Å; G595-E598 PolarHBondContact O-N 2.9Å
596W94.7Very high96.4Very high11 Ų118.4 Ų8.44%0.0425%0.053CC..THydrogen-bonded Turntrans-54.3128.6-176.2-175.9-83.7000113.4V181 S186 S187 R188 Y191 M194 Y202 E598V181-W596 HydrophobicContact CG2-CH2 4.26Å; V181-W596 HydrophobicContact CG2-CZ2 3.7Å; S186-W596 PolarHBondContact O-NE1 2.82Å; S186-W596 PolarHBondContact OG-NE1 3.29Å; S187-W596 PolarHBondContact O-NE1 3.22Å; R188-W596 HydrophobicContact CG-CB 4.38Å; Y191-W596 AromaticContact CD2-CD2 4Å; Y191-W596 HydrophobicContact CD2-CD2 4Å; Y191-W596 AromaticContact CD2-CE3 3.62Å; Y191-W596 HydrophobicContact CD2-CE3 3.62Å; Y191-W596 AromaticContact CD2-CH2 3.72Å; Y191-W596 HydrophobicContact CD2-CH2 3.72Å; Y191-W596 HydrophobicContact CD2-CZ2 4.13Å; Y191-W596 AromaticContact CD2-CZ3 3.48Å; Y191-W596 HydrophobicContact CD2-CZ3 3.48Å; Y191-W596 VanDerWaalsContact CD2-CZ3 3.48Å; Y191-W596 HydrophobicContact CE2-CE3 4.21Å; Y191-W596 HydrophobicContact CE2-CZ3 4.01Å; Y191-W596 AromaticContact CG-CD2 3.92Å; Y191-W596 HydrophobicContact CG-CD2 3.92Å; Y191-W596 AromaticContact CG-CE3 3.98Å; Y191-W596 HydrophobicContact CG-CE3 3.98Å; Y191-W596 HydrophobicContact CG-CG 4.3Å; Y191-W596 HydrophobicContact CG-CH2 4.45Å; Y191-W596 HydrophobicContact CG-CZ2 4.45Å; Y191-W596 HydrophobicContact CG-CZ3 4.26Å; M194-W596 HydrophobicContact CE-CZ2 3.99Å; Y202-W596 AromaticContact CD2-CE3 3.99Å; Y202-W596 HydrophobicContact CD2-CE3 3.99Å; W596-E598 VanDerWaalsContact C-N 3.29Å; W596-E598 PolarHBondContact O-N 2.98Å
597G95.2Very high96.4Very high38 Ų388.6 Ų8.639%0.3925%0.054SC..THydrogen-bonded Turntrans85.7-10.6179.100000115S186 N590 G595S186-G597 WeakPolarHBondContact OG-CA 3.41Å; N590-G597 WeakPolarHBondContact OD1-CA 3.13Å; N590-G597 PolarHBondContact OD1-N 2.97Å; G595-G597 PolarHBondContact O-N 3.45Å
598E94.7Very high96.4Very high50 Ų508.6 Ų8.623%0.2345%0.054CC..SBendtrans-97.1-9.3-176.9-55.4-68.6176.600112.9R413 F554 V594 G595 W596R413-E598 IonicContact CZ-OE1 2.71Å; R413-E598 IonicContact NH1-OE1 3.3Å; R413-E598 IonicContact NH2-OE1 3.66Å; R413-E598 PolarHBondContact NH2-OE1 3.04Å; F554-E598 WeakPolarHBondContact CE2-OE2 3.36Å; V594-E598 HydrophobicContact CB-CB 4.17Å; V594-E598 HydrophobicContact CG1-CB 3.91Å; V594-E598 HydrophobicContact CG1-CG 4.23Å; G595-E598 WeakPolarHBondContact O-CB 3.3Å; G595-E598 PolarHBondContact O-N 2.9Å; W596-E598 VanDerWaalsContact C-N 3.29Å; W596-E598 PolarHBondContact O-N 2.98Å
599V96.7Very high96.3Very high4 Ų410.4 Ų10.42%0.0246%0.064CC..  trans-148142.9-168.2-174.20000111.6T550 D551 S552 N590 G591 G592 V594 N601T550-V599 HydrophobicContact CG2-CG1 3.44Å; T550-V599 VanDerWaalsContact CG2-CG1 3.44Å; D551-V599 WeakPolarHBondContact O-CG1 3.48Å; S552-V599 WeakPolarHBondContact OG-CG2 3.15Å; N590-V599 WeakPolarHBondContact CA-O 3.5Å; N590-V599 PolarHBondContact OD1-O 2.9Å; G591-V599 PolarHBondContact N-O 3.5Å; G592-V599 WeakPolarHBondContact O-CG1 3.31Å; V594-V599 HydrophobicContact CB-CG2 3.69Å; V594-V599 HydrophobicContact CG2-CG2 3.87Å; V599-N601 HydrophobicContact CG1-CB 3.89Å
600I98.6Very high96.3Very high40 Ų4011.2 Ų11.221%0.2057%0.072CC..EExtended strand (participates in β ladder)trans-117.6121.4159.9-59.3-63.2000108.2M180 T550 D551 A568 A571 V572 L588 N590M180-I600 HydrophobicContact CE-CD1 4.26Å; T550-I600 WeakPolarHBondContact CA-O 3.37Å; D551-I600 PolarHBondContact N-O 2.84Å; D551-I600 PolarHBondContact O-N 3.05Å; D551-I600 VanDerWaalsContact O-N 3.09Å; A568-I600 HydrophobicContact CB-CB 3.98Å; A568-I600 HydrophobicContact CB-CG1 3.77Å; A568-I600 HydrophobicContact CB-CG2 4.42Å; A571-I600 HydrophobicContact CB-CB 4.39Å; A571-I600 HydrophobicContact CB-CG2 3.92Å; A571-I600 VanDerWaalsContact CB-O 3.3Å; A571-I600 WeakPolarHBondContact CB-O 3.25Å; V572-I600 HydrophobicContact CG2-CG2 4.5Å; L588-I600 HydrophobicContact CD1-CG2 3.7Å; L588-I600 HydrophobicContact CG-CG2 4.29Å; N590-I600 HydrophobicContact CB-CD1 4.44Å
601N98.8Very high96.3Very high0 Ų012.8 Ų12.80%08%0.083CC..EExtended strand (participates in β ladder)trans-138.2132.7-16961.8-69.7000112.7Q204 H544 G549 T550 H589 G592 V599Q204-N601 PolarHBondContact O-ND2 3.29Å; H544-N601 HydrophobicContact CB-CB 3.92Å; H544-N601 PolarHBondContact ND1-ND2 3.04Å; H544-N601 PolarHBondContact ND1-O 3.27Å; G549-N601 CarbonylContact O-C 3.56Å; G549-N601 WeakPolarHBondContact O-CA 3.46Å; T550-N601 HydrophobicContact CG2-CB 3.73Å; T550-N601 WeakPolarHBondContact OG1-CB 3.48Å; H589-N601 WeakPolarHBondContact CA-O 3.24Å; H589-N601 WeakPolarHBondContact CB-O 3.17Å; H589-N601 PolarHBondContact N-O 3.03Å; H589-N601 PolarHBondContact O-N 3.39Å; H589-N601 PolarHBondContact O-OD1 2.84Å; H589-N601 VanDerWaalsContact O-OD1 3.13Å; G592-N601 WeakPolarHBondContact CA-OD1 3.3Å; G592-N601 PolarHBondContact N-OD1 3.18Å; V599-N601 HydrophobicContact CG1-CB 3.89Å
602G98.4Very high96.5Very high0 Ų019 Ų190%012%0.117CC..EExtended strand (participates in β ladder)trans-130.1158.9-176.500000114.6R542 H544 G549 A587R542-G602 PolarHBondContact NH1-O 3.09Å; R542-G602 PolarHBondContact NH2-O 3.22Å; H544-G602 WeakPolarHBondContact CB-O 3.45Å; H544-G602 VanDerWaalsContact CG-C 3.5Å; H544-G602 VanDerWaalsContact CG-O 3.3Å; H544-G602 PolarHBondContact ND1-N 3.22Å; G549-G602 PolarHBondContact O-N 3.07Å; A587-G602 CarbonylContact O-C 3.21Å; A587-G602 WeakPolarHBondContact O-CA 3.43Å
603G98.3Very high96.6Very high1 Ų122.5 Ų22.51%0.0113%0.133CC..EExtended strand (participates in β ladder)trans-157.5176.6-178.700000112.3A587A587-G603 PolarHBondContact N-O 2.86Å; A587-G603 PolarHBondContact O-N 2.89Å
604F98.8Very high97Very high3 Ų322.3 Ų22.31%0.01313%0.131CC..EExtended strand (participates in β ladder)trans-140.7164.8-175.774.4-92.9000111.4I540 S541 R542 A583 W585 L606 M621 L622 D625I540-F604 HydrophobicContact CG2-CE2 4.23Å; I540-F604 HydrophobicContact CG2-CZ 4.37Å; S541-F604 WeakPolarHBondContact CB-O 3.38Å; S541-F604 PolarHBondContact OG-O 2.68Å; R542-F604 HydrophobicContact CG-CD1 4.09Å; R542-F604 HydrophobicContact CG-CE1 3.63Å; R542-F604 HydrophobicContact CG-CZ 4.33Å; A583-F604 HydrophobicContact CB-CB 4.35Å; W585-F604 CarbonylContact O-C 3.53Å; W585-F604 VanDerWaalsContact O-CA 3.32Å; W585-F604 WeakPolarHBondContact O-CA 3.42Å; F604-L606 HydrophobicContact CD2-CB 4.14Å; F604-L606 HydrophobicContact CE2-CB 4.1Å; F604-M621 HydrophobicContact CB-SD 4.39Å; F604-M621 HydrophobicContact CD1-CE 4.04Å; F604-M621 HydrophobicContact CD2-CE 3.38Å; F604-M621 HydrophobicContact CD2-SD 3.62Å; F604-M621 HydrophobicContact CE1-CE 3.82Å; F604-M621 HydrophobicContact CE2-CE 3.17Å; F604-M621 HydrophobicContact CE2-SD 4.05Å; F604-M621 HydrophobicContact CG-CE 3.85Å; F604-M621 HydrophobicContact CG-SD 3.93Å; F604-M621 HydrophobicContact CZ-CE 3.41Å; F604-M621 VanDerWaalsContact CZ-CE 3.41Å; F604-L622 HydrophobicContact CE1-CD2 4.42Å; F604-L622 HydrophobicContact CE2-CD2 4.49Å; F604-L622 HydrophobicContact CZ-CD2 3.8Å; F604-D625 WeakPolarHBondContact CE1-OD2 3.47Å
605G98.6Very high97.5Very high0 Ų023.1 Ų23.10%014%0.138CC..EExtended strand (participates in β ladder)trans-131.1145.6156.200000110.9I540 T584 W585I540-G605 CarbonylContact O-C 3.23Å; I540-G605 WeakPolarHBondContact O-CA 3.12Å; T584-G605 WeakPolarHBondContact CA-O 3.35Å; T584-G605 WeakPolarHBondContact CB-O 3.24Å; T584-G605 PolarHBondContact N-O 3.26Å; W585-G605 VanDerWaalsContact CE2-CA 3.49Å; W585-G605 PolarHBondContact N-O 3.43Å; W585-G605 PolarHBondContact O-N 3.43Å
606L98.8Very high97.9Very high0 Ų029.4 Ų29.40%017%0.165CC..EExtended strand (participates in β ladder)trans-137.7119.9-176.8-178.372.6000110.1V539 I540 G582 F604 L608 R617 A618 M621V539-L606 CarbonylContact C-O 3.6Å; V539-L606 WeakPolarHBondContact CA-O 3.03Å; I540-L606 PolarHBondContact N-O 3.08Å; I540-L606 PolarHBondContact O-N 3.47Å; G582-L606 WeakPolarHBondContact O-CD1 3.24Å; F604-L606 HydrophobicContact CD2-CB 4.14Å; F604-L606 HydrophobicContact CE2-CB 4.1Å; L606-L608 HydrophobicContact CD2-CD2 4.25Å; L606-R617 HydrophobicContact CD1-CB 4.19Å; L606-A618 VanDerWaalsContact CD2-CA 3.47Å; L606-A618 HydrophobicContact CD2-CB 3.68Å; L606-M621 HydrophobicContact CB-CE 4.41Å; L606-M621 HydrophobicContact CB-SD 4.31Å; L606-M621 HydrophobicContact CD1-SD 4.41Å; L606-M621 HydrophobicContact CD2-CE 4.11Å; L606-M621 HydrophobicContact CD2-SD 4.35Å
607L98.8Very high98Very high4 Ų430.7 Ų30.72%0.02117%0.169CC..EExtended strand (participates in β ladder)trans-82.6125.7175.5-171.668.6000110.9R98 Q99 A102 T454 P537 V539 T584 D609R98-L607 HydrophobicContact CB-CD2 4.05Å; Q99-L607 HydrophobicContact CB-CD2 4.45Å; Q99-L607 HydrophobicContact CG-CB 4.32Å; Q99-L607 HydrophobicContact CG-CD2 3.88Å; A102-L607 HydrophobicContact CB-CD1 3.78Å; A102-L607 HydrophobicContact CB-CD2 4.42Å; T454-L607 HydrophobicContact CG2-CD1 4.45Å; P537-L607 HydrophobicContact CB-CD1 3.64Å; P537-L607 HydrophobicContact CB-CD2 4.46Å; P537-L607 HydrophobicContact CB-CG 4.14Å; V539-L607 HydrophobicContact CG2-CD1 3.78Å; T584-L607 HydrophobicContact CG2-CB 4.47Å; T584-L607 PolarHBondContact OG1-N 3.15Å; L607-D609 HydrophobicContact CD2-CB 4.44Å
608L98.9Very high98.2Very high0 Ų028.9 Ų28.90%015%0.151CC..EExtended strand (participates in β ladder)trans-99.6103.3168.2-56.3-178.8000108.5A522 I525 N526 P537 V538 I540 L606 A618A522-L608 HydrophobicContact CB-CD1 4.22Å; A522-L608 VanDerWaalsContact O-CD1 3.27Å; A522-L608 WeakPolarHBondContact O-CD1 3.36Å; I525-L608 HydrophobicContact CB-CD1 4.11Å; I525-L608 HydrophobicContact CG2-CD1 3.85Å; N526-L608 HydrophobicContact CB-CB 4.2Å; N526-L608 HydrophobicContact CB-CD1 4.37Å; N526-L608 HydrophobicContact CB-CD2 4.35Å; N526-L608 WeakPolarHBondContact OD1-CB 3.43Å; P537-L608 CarbonylContact C-O 3.58Å; P537-L608 WeakPolarHBondContact CA-O 3.36Å; P537-L608 WeakPolarHBondContact CB-O 3.25Å; V538-L608 PolarHBondContact N-O 3.05Å; V538-L608 WeakPolarHBondContact O-CB 3.27Å; V538-L608 PolarHBondContact O-N 3.5Å; I540-L608 HydrophobicContact CD1-CD1 3.76Å; I540-L608 HydrophobicContact CG1-CD1 3.39Å; I540-L608 HydrophobicContact CG1-CD2 4.48Å; I540-L608 HydrophobicContact CG1-CG 3.78Å; L606-L608 HydrophobicContact CD2-CD2 4.25Å; L608-A618 HydrophobicContact CD2-CB 4.01Å
609D98.4Very high98.3Very high53 Ų5332.6 Ų32.628%0.28316%0.162SC..  trans-104.28.2-175.366.2-3.4000113.7N526 P537 L607 S611 A614N526-D609 PolarHBondContact OD1-N 3.2Å; P537-D609 HydrophobicContact CB-CB 4.38Å; P537-D609 HydrophobicContact CG-CB 4.23Å; L607-D609 HydrophobicContact CD2-CB 4.44Å; D609-S611 VanDerWaalsContact C-N 3.32Å; D609-S611 WeakPolarHBondContact OD1-CB 3.44Å; D609-S611 PolarHBondContact OD1-N 3.34Å; D609-S611 PolarHBondContact OD1-OG 3.36Å; D609-A614 VanDerWaalsContact OD1-CB 3.29Å; D609-A614 WeakPolarHBondContact OD1-CB 3.47Å
610G98.6Very high98.4Very high16 Ų1635 Ų3517%0.16518%0.18CC..SBendtrans87-4.7-177.300000114.2N526 A530N526-G610 WeakPolarHBondContact O-CA 3.39Å; N526-G610 WeakPolarHBondContact OD1-CA 3.46Å; N526-G610 PolarHBondContact OD1-N 2.95Å; A530-G610 WeakPolarHBondContact CB-O 3.3Å
611S98.4Very high98.4Very high39 Ų3933.1 Ų33.127%0.27317%0.17SC..  trans-77.9153.5179.669.30000112.8N526 D609 E613 A614 A615N526-S611 PolarHBondContact ND2-O 3.08Å; D609-S611 VanDerWaalsContact C-N 3.32Å; D609-S611 WeakPolarHBondContact OD1-CB 3.44Å; D609-S611 PolarHBondContact OD1-N 3.34Å; D609-S611 PolarHBondContact OD1-OG 3.36Å; S611-E613 PolarHBondContact O-N 3.34Å; S611-A614 PolarHBondContact O-N 3.08Å; S611-A614 WeakPolarHBondContact OG-CB 3.46Å; S611-A614 PolarHBondContact OG-N 3.41Å; S611-A615 PolarHBondContact O-N 3Å; S611-A615 VanDerWaalsContact O-N 3.16Å
612D98.4Very high98.4Very high131 Ų13133.1 Ų33.170%0.70117%0.17SC*.Hα-helixtrans-58.9-30.7168.9-73.1-23.6000112A615 K616D612-A615 WeakPolarHBondContact O-CB 3.43Å; D612-A615 PolarHBondContact O-N 3.24Å; D612-K616 WeakPolarHBondContact O-CG 3.04Å; D612-K616 PolarHBondContact O-N 2.91Å
613E97.3Very high98.3Very high73 Ų7335.1 Ų35.134%0.34118%0.181SC..Hα-helixtrans-70.6-43.2179.5179.854.8-154.700111.2S611 A615 K616 R617S611-E613 PolarHBondContact O-N 3.34Å; E613-A615 VanDerWaalsContact C-N 3.28Å; E613-A615 PolarHBondContact O-N 3.39Å; E613-K616 PolarHBondContact O-N 3.06Å; E613-R617 VanDerWaalsContact O-CG 3.31Å; E613-R617 WeakPolarHBondContact O-CG 3.12Å; E613-R617 PolarHBondContact O-N 2.73Å; E613-R617 IonicContact OE1-CZ 3.85Å; E613-R617 IonicContact OE1-NE 3.37Å; E613-R617 PolarHBondContact OE1-NE 3.15Å; E613-R617 IonicContact OE1-NH2 3.79Å; E613-R617 PolarHBondContact OE1-NH2 3.45Å
614A98.3Very high98.3Very high1 Ų137.6 Ų37.61%0.00819%0.19CC..Hα-helixtrans-60-38.8170.700000111.9D609 S611 R617 A618D609-A614 VanDerWaalsContact OD1-CB 3.29Å; D609-A614 WeakPolarHBondContact OD1-CB 3.47Å; S611-A614 PolarHBondContact O-N 3.08Å; S611-A614 WeakPolarHBondContact OG-CB 3.46Å; S611-A614 PolarHBondContact OG-N 3.41Å; A614-R617 PolarHBondContact O-N 3Å; A614-A618 VanDerWaalsContact O-CB 3.32Å; A614-A618 WeakPolarHBondContact O-CB 3.48Å; A614-A618 PolarHBondContact O-N 3.28Å
615A98.5Very high98.3Very high19 Ų1937.5 Ų37.516%0.15719%0.189CC..Hα-helixtrans-62.9-41.9174.900000112.8L523 S611 D612 E613 R619L523-A615 HydrophobicContact CD2-CB 3.69Å; S611-A615 PolarHBondContact O-N 3Å; S611-A615 VanDerWaalsContact O-N 3.16Å; D612-A615 WeakPolarHBondContact O-CB 3.43Å; D612-A615 PolarHBondContact O-N 3.24Å; E613-A615 VanDerWaalsContact C-N 3.28Å; E613-A615 PolarHBondContact O-N 3.39Å; A615-R619 WeakPolarHBondContact O-CB 3.46Å; A615-R619 PolarHBondContact O-N 2.92Å
616K98.4Very high98.3Very high135 Ų13537.6 Ų37.659%0.58719%0.19SC*.Hα-helixtrans-62.9-46.4175.4-73.3170-172.8170.50111.8D612 E613 R619 S620D612-K616 WeakPolarHBondContact O-CG 3.04Å; D612-K616 PolarHBondContact O-N 2.91Å; E613-K616 PolarHBondContact O-N 3.06Å; K616-R619 PolarHBondContact O-N 3.4Å; K616-S620 WeakPolarHBondContact O-CB 3.38Å; K616-S620 PolarHBondContact O-N 2.95Å
617R98.1Very high98.3Very high38 Ų3838 Ų3814%0.14319%0.193CC..Hα-helixtrans-61.7-46.9177-65.2175.4-158.6169.62111.5Q99 G582 L606 E613 A614 R619 S620 M621Q99-R617 VanDerWaalsContact NE2-NH1 3.15Å; G582-R617 WeakPolarHBondContact O-CD 3.4Å; L606-R617 HydrophobicContact CD1-CB 4.19Å; E613-R617 VanDerWaalsContact O-CG 3.31Å; E613-R617 WeakPolarHBondContact O-CG 3.12Å; E613-R617 PolarHBondContact O-N 2.73Å; E613-R617 IonicContact OE1-CZ 3.85Å; E613-R617 IonicContact OE1-NE 3.37Å; E613-R617 PolarHBondContact OE1-NE 3.15Å; E613-R617 IonicContact OE1-NH2 3.79Å; E613-R617 PolarHBondContact OE1-NH2 3.45Å; A614-R617 PolarHBondContact O-N 3Å; R617-R619 VanDerWaalsContact C-N 3.34Å; R617-R619 PolarHBondContact O-N 3.34Å; R617-S620 PolarHBondContact O-N 3.47Å; R617-M621 VanDerWaalsContact O-CB 3.29Å; R617-M621 WeakPolarHBondContact O-CB 3.37Å; R617-M621 PolarHBondContact O-N 2.97Å
618A98.4Very high98.2Very high0 Ų038.9 Ų38.90%020%0.198CC..Hα-helixtrans-57.1-46.6177.300000112.1A522 L606 L608 A614 L622A522-A618 HydrophobicContact CB-CB 4.22Å; L606-A618 VanDerWaalsContact CD2-CA 3.47Å; L606-A618 HydrophobicContact CD2-CB 3.68Å; L608-A618 HydrophobicContact CD2-CB 4.01Å; A614-A618 VanDerWaalsContact O-CB 3.32Å; A614-A618 WeakPolarHBondContact O-CB 3.48Å; A614-A618 PolarHBondContact O-N 3.28Å; A618-L622 HydrophobicContact CB-CD1 4.49Å; A618-L622 VanDerWaalsContact O-CB 3.23Å; A618-L622 WeakPolarHBondContact O-CB 3.25Å; A618-L622 VanDerWaalsContact O-CG 3.27Å; A618-L622 WeakPolarHBondContact O-CG 3.4Å; A618-L622 PolarHBondContact O-N 3.36Å
619R98.1Very high98.2Very high127 Ų12738.9 Ų38.948%0.47920%0.198SC..Hα-helixtrans-62.8-46.3177-169.5-174.2-55.7-80.81.2111.8V519 A615 K616 R617 N623V519-R619 HydrophobicContact CG1-CG 4.28Å; A615-R619 WeakPolarHBondContact O-CB 3.46Å; A615-R619 PolarHBondContact O-N 2.92Å; K616-R619 PolarHBondContact O-N 3.4Å; R617-R619 VanDerWaalsContact C-N 3.34Å; R617-R619 PolarHBondContact O-N 3.34Å; R619-N623 VanDerWaalsContact O-CB 3.28Å; R619-N623 WeakPolarHBondContact O-CB 3.35Å; R619-N623 PolarHBondContact O-N 2.96Å; R619-N623 PolarHBondContact O-ND2 2.85Å
620S97.8Very high98.2Very high55 Ų5536.5 Ų36.539%0.38519%0.185SC..Hα-helixtrans-65.8-51.2-177.4-168.20000112K616 R617 W624K616-S620 WeakPolarHBondContact O-CB 3.38Å; K616-S620 PolarHBondContact O-N 2.95Å; R617-S620 PolarHBondContact O-N 3.47Å; S620-W624 PolarHBondContact O-N 2.89Å
621M98.3Very high98.2Very high0 Ų036.8 Ų36.80%019%0.186CC..Hα-helixtrans-68.4-50-175.9-172.1-150.97800111.9D578 R581 A583 F604 L606 R617 N623 W624 D625D578-M621 HydrophobicContact CB-CG 4.26Å; R581-M621 HydrophobicContact CB-CB 4.15Å; A583-M621 HydrophobicContact CB-CG 4.38Å; A583-M621 HydrophobicContact CB-SD 3.69Å; F604-M621 HydrophobicContact CB-SD 4.39Å; F604-M621 HydrophobicContact CD1-CE 4.04Å; F604-M621 HydrophobicContact CD2-CE 3.38Å; F604-M621 HydrophobicContact CD2-SD 3.62Å; F604-M621 HydrophobicContact CE1-CE 3.82Å; F604-M621 HydrophobicContact CE2-CE 3.17Å; F604-M621 HydrophobicContact CE2-SD 4.05Å; F604-M621 HydrophobicContact CG-CE 3.85Å; F604-M621 HydrophobicContact CG-SD 3.93Å; F604-M621 HydrophobicContact CZ-CE 3.41Å; F604-M621 VanDerWaalsContact CZ-CE 3.41Å; L606-M621 HydrophobicContact CB-CE 4.41Å; L606-M621 HydrophobicContact CB-SD 4.31Å; L606-M621 HydrophobicContact CD1-SD 4.41Å; L606-M621 HydrophobicContact CD2-CE 4.11Å; L606-M621 HydrophobicContact CD2-SD 4.35Å; R617-M621 VanDerWaalsContact O-CB 3.29Å; R617-M621 WeakPolarHBondContact O-CB 3.37Å; R617-M621 PolarHBondContact O-N 2.97Å; M621-N623 VanDerWaalsContact C-N 3.28Å; M621-N623 PolarHBondContact O-N 3.26Å; M621-W624 PolarHBondContact O-N 3.06Å; M621-D625 WeakPolarHBondContact O-CB 3.15Å; M621-D625 PolarHBondContact O-N 2.9Å
622L98.4Very high98.2Very high0 Ų036.5 Ų36.50%018%0.179CC..Hα-helixtrans-67.3-28.2-176.9-65.5170.6000113F449 R518 V519 A522 F604 A618 V626F449-L622 HydrophobicContact CE2-CD1 4.29Å; F449-L622 HydrophobicContact CE2-CD2 4.43Å; R518-L622 HydrophobicContact CB-CD1 4.3Å; R518-L622 HydrophobicContact CB-CD2 4.46Å; V519-L622 HydrophobicContact CG2-CB 3.78Å; V519-L622 HydrophobicContact CG2-CD1 4.48Å; A522-L622 HydrophobicContact CB-CD1 3.67Å; F604-L622 HydrophobicContact CE1-CD2 4.42Å; F604-L622 HydrophobicContact CE2-CD2 4.49Å; F604-L622 HydrophobicContact CZ-CD2 3.8Å; A618-L622 HydrophobicContact CB-CD1 4.49Å; A618-L622 VanDerWaalsContact O-CB 3.23Å; A618-L622 WeakPolarHBondContact O-CB 3.25Å; A618-L622 VanDerWaalsContact O-CG 3.27Å; A618-L622 WeakPolarHBondContact O-CG 3.4Å; A618-L622 PolarHBondContact O-N 3.36Å; L622-V626 PolarHBondContact O-N 3.21Å
623N97.3Very high98.1Very high42 Ų4230.4 Ų30.423%0.22515%0.146CC..Hα-helixtrans-63-45170.9-81.4-25.2000111.2Q515 R619 M621 S627Q515-N623 PolarHBondContact NE2-OD1 2.7Å; R619-N623 VanDerWaalsContact O-CB 3.28Å; R619-N623 WeakPolarHBondContact O-CB 3.35Å; R619-N623 PolarHBondContact O-N 2.96Å; R619-N623 PolarHBondContact O-ND2 2.85Å; M621-N623 VanDerWaalsContact C-N 3.28Å; M621-N623 PolarHBondContact O-N 3.26Å; N623-S627 WeakPolarHBondContact O-CB 3.41Å; N623-S627 PolarHBondContact O-N 3.18Å; N623-S627 PolarHBondContact O-OG 2.95Å
624W98.3Very high98.1Very high54 Ų5427 Ų2721%0.20513%0.13CC..Hα-helixtrans-69.9-50.6177.7166.7-100.6000112.6Q573 N574 G577 S620 M621 V626 S627 N628Q573-W624 HydrophobicContact CB-CZ2 4.36Å; Q573-W624 WeakPolarHBondContact O-CZ2 3.29Å; N574-W624 PolarHBondContact O-NE1 3.05Å; G577-W624 VanDerWaalsContact C-CD1 3.47Å; G577-W624 VanDerWaalsContact CA-NE1 3.3Å; S620-W624 PolarHBondContact O-N 2.89Å; M621-W624 PolarHBondContact O-N 3.06Å; W624-V626 PolarHBondContact O-N 2.86Å; W624-S627 PolarHBondContact O-N 3.29Å; W624-N628 HydrophobicContact CD2-CB 4.13Å; W624-N628 HydrophobicContact CE3-CB 4.16Å; W624-N628 HydrophobicContact CH2-CB 3.88Å; W624-N628 HydrophobicContact CZ2-CB 3.84Å; W624-N628 HydrophobicContact CZ3-CB 4.04Å; W624-N628 VanDerWaalsContact O-CB 3.27Å; W624-N628 WeakPolarHBondContact O-CB 3.46Å; W624-N628 PolarHBondContact O-N 3.32Å
625D98.6Very high98.1Very high0 Ų033.8 Ų33.80%016%0.156CC..Hα-helixtrans-55.5-26.7-176.5-176.461.1000112.5R518 R542 S548 N574 F604 M621R518-D625 IonicContact NH1-OD2 3.9Å; R518-D625 PolarHBondContact NH1-OD2 3.16Å; R542-D625 IonicContact CZ-OD1 3.27Å; R542-D625 IonicContact CZ-OD2 3.61Å; R542-D625 IonicContact NE-OD1 3.76Å; R542-D625 PolarHBondContact NE-OD1 3.08Å; R542-D625 IonicContact NE-OD2 2.75Å; R542-D625 PolarHBondContact NE-OD2 3.16Å; R542-D625 IonicContact NH2-OD1 3.54Å; R542-D625 PolarHBondContact NH2-OD1 3.23Å; R542-D625 IonicContact NH2-OD2 3.74Å; S548-D625 WeakPolarHBondContact CB-O 3.33Å; S548-D625 PolarHBondContact OG-O 3.48Å; N574-D625 PolarHBondContact ND2-OD1 3.31Å; F604-D625 WeakPolarHBondContact CE1-OD2 3.47Å; M621-D625 WeakPolarHBondContact O-CB 3.15Å; M621-D625 PolarHBondContact O-N 2.9Å
626V98.4Very high97.9Very high2 Ų233.4 Ų33.41%0.01215%0.152CC..Hα-helixtrans-95.9-51.1173.5-179.60000112.3Q515 V547 S548 L622 W624 N628 G629 V630Q515-V626 HydrophobicContact CB-CB 3.91Å; Q515-V626 HydrophobicContact CB-CG1 3.72Å; Q515-V626 HydrophobicContact CB-CG2 4.37Å; Q515-V626 HydrophobicContact CG-CB 4.37Å; V547-V626 HydrophobicContact CG1-CG1 4.19Å; S548-V626 PolarHBondContact OG-O 3.32Å; L622-V626 PolarHBondContact O-N 3.21Å; W624-V626 PolarHBondContact O-N 2.86Å; V626-N628 VanDerWaalsContact C-N 3.27Å; V626-N628 PolarHBondContact O-N 3.48Å; V626-G629 PolarHBondContact O-N 3.37Å; V626-V630 HydrophobicContact CG1-CG2 4.12Å; V626-V630 WeakPolarHBondContact O-CG2 3.23Å; V626-V630 PolarHBondContact O-N 2.79Å
627S98.1Very high97.7Very high10 Ų1029.8 Ų29.87%0.0715%0.152CC..Hα-helixtrans-63.8-29.8-172.6-70.20000113.6Q515 N623 W624 V630 A631Q515-S627 PolarHBondContact OE1-OG 2.97Å; N623-S627 WeakPolarHBondContact O-CB 3.41Å; N623-S627 PolarHBondContact O-N 3.18Å; N623-S627 PolarHBondContact O-OG 2.95Å; W624-S627 PolarHBondContact O-N 3.29Å; S627-V630 PolarHBondContact O-N 3.46Å; S627-A631 VanDerWaalsContact O-CB 3.24Å; S627-A631 WeakPolarHBondContact O-CB 3.41Å; S627-A631 PolarHBondContact O-N 3.27Å
628N98.4Very high97.4Very high22 Ų2229 Ų2912%0.11815%0.151CC..Hα-helixtrans-56.4-55.2178.1174.536.3000111.6M570 N574 W624 V626 A631 R632M570-N628 PolarHBondContact O-ND2 3.19Å; N574-N628 WeakPolarHBondContact CB-ND2 3.42Å; N574-N628 PolarHBondContact OD1-ND2 3.08Å; W624-N628 HydrophobicContact CD2-CB 4.13Å; W624-N628 HydrophobicContact CE3-CB 4.16Å; W624-N628 HydrophobicContact CH2-CB 3.88Å; W624-N628 HydrophobicContact CZ2-CB 3.84Å; W624-N628 HydrophobicContact CZ3-CB 4.04Å; W624-N628 VanDerWaalsContact O-CB 3.27Å; W624-N628 WeakPolarHBondContact O-CB 3.46Å; W624-N628 PolarHBondContact O-N 3.32Å; V626-N628 VanDerWaalsContact C-N 3.27Å; V626-N628 PolarHBondContact O-N 3.48Å; N628-A631 PolarHBondContact O-N 3.44Å; N628-R632 PolarHBondContact O-N 3.06Å
629G97.8Very high97.2Very high0 Ų033.8 Ų33.80%018%0.18CC..Hα-helixtrans-71.2-34.3-179.400000113S548 V626 R632 R633S548-G629 WeakPolarHBondContact OG-CA 3.43Å; S548-G629 PolarHBondContact OG-N 3.44Å; V626-G629 PolarHBondContact O-N 3.37Å; G629-R632 PolarHBondContact O-N 3.09Å; G629-R633 VanDerWaalsContact O-CB 3.31Å; G629-R633 WeakPolarHBondContact O-CB 3.17Å; G629-R633 WeakPolarHBondContact O-CG 3.3Å; G629-R633 PolarHBondContact O-N 3.42Å
630V98.2Very high97Very high2 Ų228.5 Ų28.51%0.01216%0.162CC..Hα-helixtrans-62.7-45.4172.5-178.20000110V547 V626 S627 R632 R633 C634 A641 T644 I645V547-V630 HydrophobicContact CG2-CG2 3.88Å; V626-V630 HydrophobicContact CG1-CG2 4.12Å; V626-V630 WeakPolarHBondContact O-CG2 3.23Å; V626-V630 PolarHBondContact O-N 2.79Å; S627-V630 PolarHBondContact O-N 3.46Å; V630-R632 PolarHBondContact O-N 2.93Å; V630-R633 PolarHBondContact O-N 2.84Å; V630-C634 WeakPolarHBondContact O-CB 3.48Å; V630-C634 PolarHBondContact O-N 3.12Å; V630-A641 HydrophobicContact CG1-CB 4.15Å; V630-A641 WeakPolarHBondContact O-CB 3.27Å; V630-T644 HydrophobicContact CG1-CG2 3.83Å; V630-T644 HydrophobicContact CG2-CG2 4.5Å; V630-I645 HydrophobicContact CB-CD1 4.5Å; V630-I645 HydrophobicContact CG1-CB 3.94Å; V630-I645 HydrophobicContact CG1-CD1 4.4Å
631A98.3Very high96.9Very high22 Ų2225.9 Ų25.918%0.18214%0.143CC..Hα-helixtrans-61.9-44.217700000112S627 N628 C634 W635 I645 V657S627-A631 VanDerWaalsContact O-CB 3.24Å; S627-A631 WeakPolarHBondContact O-CB 3.41Å; S627-A631 PolarHBondContact O-N 3.27Å; N628-A631 PolarHBondContact O-N 3.44Å; A631-C634 WeakPolarHBondContact O-CB 3.39Å; A631-C634 PolarHBondContact O-N 2.79Å; A631-W635 PolarHBondContact O-N 3Å; A631-I645 HydrophobicContact CB-CD1 4.1Å; A631-I645 HydrophobicContact CB-CG1 4.11Å; A631-V657 HydrophobicContact CB-CB 4.35Å; A631-V657 HydrophobicContact CB-CG1 3.94Å
632R98.2Very high96.8Very high34 Ų3430.2 Ų30.213%0.12816%0.16CC..Hα-helixtrans-59.9-50174.5-175.6-82.2179.7105.81.3111.3D551 S564 M570 N628 G629 V630 C634 W635 S636D551-R632 IonicContact OD1-CZ 3.73Å; D551-R632 IonicContact OD1-NH1 3.76Å; D551-R632 PolarHBondContact OD1-NH1 3Å; D551-R632 IonicContact OD1-NH2 2.77Å; S564-R632 PolarHBondContact O-NH2 3.34Å; S564-R632 PolarHBondContact OG-NH2 3.26Å; M570-R632 HydrophobicContact CB-CG 4.29Å; M570-R632 HydrophobicContact CG-CB 4.25Å; M570-R632 HydrophobicContact CG-CG 4.29Å; M570-R632 HydrophobicContact SD-CB 3.93Å; M570-R632 HydrophobicContact SD-CG 3.95Å; N628-R632 PolarHBondContact O-N 3.06Å; G629-R632 PolarHBondContact O-N 3.09Å; V630-R632 PolarHBondContact O-N 2.93Å; R632-C634 VanDerWaalsContact C-N 3.27Å; R632-C634 PolarHBondContact O-N 3.37Å; R632-W635 WeakPolarHBondContact O-CB 3.42Å; R632-W635 PolarHBondContact O-N 3.21Å; R632-S636 PolarHBondContact NE-OG 3.45Å; R632-S636 PolarHBondContact O-N 3.48Å; R632-S636 PolarHBondContact O-OG 2.91Å
633R97Very high96.7Very high2 Ų234.2 Ų34.21%0.00818%0.179CC..Hα-helixtrans-62.9-34.9-179.3-72.4169.4-177.6-81-2.1112V547 E556 N559 G629 V630 S636 G637 N638 A641V547-R633 PolarHBondContact O-NE 3.13Å; E556-R633 PolarHBondContact O-NH1 3.1Å; E556-R633 PolarHBondContact O-NH2 3.18Å; N559-R633 PolarHBondContact OD1-NH1 3.28Å; G629-R633 VanDerWaalsContact O-CB 3.31Å; G629-R633 WeakPolarHBondContact O-CB 3.17Å; G629-R633 WeakPolarHBondContact O-CG 3.3Å; G629-R633 PolarHBondContact O-N 3.42Å; V630-R633 PolarHBondContact O-N 2.84Å; R633-S636 PolarHBondContact O-N 3.39Å; R633-G637 PolarHBondContact O-N 3.46Å; R633-N638 HydrophobicContact CB-CB 4.4Å; R633-N638 WeakPolarHBondContact O-CB 3.39Å; R633-N638 PolarHBondContact O-N 3.35Å; R633-A641 HydrophobicContact CB-CB 3.72Å
634C97.3Very high96.6Very high1 Ų133 Ų331%0.00717%0.173CC..Hα-helixtrans-60.5-54.8171.5170.80000110.2V630 A631 R632 S636 G637 A641 Y642 I645 P660V630-C634 WeakPolarHBondContact O-CB 3.48Å; V630-C634 PolarHBondContact O-N 3.12Å; A631-C634 WeakPolarHBondContact O-CB 3.39Å; A631-C634 PolarHBondContact O-N 2.79Å; R632-C634 VanDerWaalsContact C-N 3.27Å; R632-C634 PolarHBondContact O-N 3.37Å; C634-S636 PolarHBondContact O-N 3.43Å; C634-G637 PolarHBondContact O-N 3Å; C634-A641 HydrophobicContact CB-CB 3.94Å; C634-A641 VanDerWaalsContact N-CB 3.31Å; C634-Y642 VanDerWaalsContact SG-CA 3.54Å; C634-I645 HydrophobicContact CB-CG2 3.89Å; C634-P660 WeakPolarHBondContact O-CG 3.49Å; C634-P660 VanDerWaalsContact SG-CD 3.54Å
635W97.9Very high96.6Very high145 Ų14530.4 Ų30.455%0.54916%0.163SC..Hα-helixtrans-53.5-40.9178.4179.1-101.9000112.4A631 R632 G637 T658 P660A631-W635 PolarHBondContact O-N 3Å; R632-W635 WeakPolarHBondContact O-CB 3.42Å; R632-W635 PolarHBondContact O-N 3.21Å; W635-G637 PolarHBondContact O-N 3.48Å; W635-G637 VanDerWaalsContact O-N 3.14Å; W635-T658 HydrophobicContact CE3-CG2 4.1Å; W635-T658 HydrophobicContact CH2-CG2 4.34Å; W635-T658 HydrophobicContact CZ3-CG2 3.54Å; W635-P660 HydrophobicContact CE3-CB 4.14Å; W635-P660 HydrophobicContact CZ3-CB 4.39Å
636S95.6Very high96.5Very high11 Ų1134 Ų348%0.07718%0.18CC..THydrogen-bonded Turntrans-76.812.2177.3-60.80000115.4D562 S564 R632 R633 C634D562-S636 VanDerWaalsContact CG-OG 3.3Å; D562-S636 PolarHBondContact OD1-OG 3.41Å; D562-S636 VanDerWaalsContact OD2-CA 3.29Å; D562-S636 WeakPolarHBondContact OD2-CA 3.06Å; D562-S636 WeakPolarHBondContact OD2-CB 3.47Å; D562-S636 PolarHBondContact OD2-OG 2.9Å; S564-S636 PolarHBondContact OG-OG 3Å; R632-S636 PolarHBondContact NE-OG 3.45Å; R632-S636 PolarHBondContact O-N 3.48Å; R632-S636 PolarHBondContact O-OG 2.91Å; R633-S636 PolarHBondContact O-N 3.39Å; C634-S636 PolarHBondContact O-N 3.43Å
637G92.6Very high96.3Very high58 Ų5838.1 Ų38.160%0.59820%0.195SC*.THydrogen-bonded Turntrans94.59.6169.600000116.1R633 C634 W635 T639R633-G637 PolarHBondContact O-N 3.46Å; C634-G637 PolarHBondContact O-N 3Å; W635-G637 PolarHBondContact O-N 3.48Å; W635-G637 VanDerWaalsContact O-N 3.14Å; G637-T639 PolarHBondContact O-N 3.42Å
638N93.6Very high96.1Very high23 Ų2338.2 Ų38.212%0.12320%0.195CC..  trans-80.9120.2177.8-169.3-70.3000112.1S443 R633 N640 A641 Y642S443-N638 VanDerWaalsContact CB-CG 3.46Å; S443-N638 WeakPolarHBondContact CB-OD1 3.33Å; S443-N638 PolarHBondContact OG-ND2 3.11Å; S443-N638 PolarHBondContact OG-OD1 3.32Å; R633-N638 HydrophobicContact CB-CB 4.4Å; R633-N638 WeakPolarHBondContact O-CB 3.39Å; R633-N638 PolarHBondContact O-N 3.35Å; N638-N640 WeakPolarHBondContact OD1-CA 3.41Å; N638-N640 VanDerWaalsContact OD1-CB 3.28Å; N638-N640 WeakPolarHBondContact OD1-CB 3.25Å; N638-N640 PolarHBondContact OD1-N 2.98Å; N638-A641 HydrophobicContact CB-CB 4.05Å; N638-A641 PolarHBondContact O-N 2.96Å; N638-A641 PolarHBondContact OD1-N 3.37Å; N638-A641 VanDerWaalsContact OD1-N 3.16Å; N638-Y642 PolarHBondContact O-N 2.84Å
639T92.9Very high96.1Very high100 Ų10039.1 Ų39.161%0.61320%0.199SC*.Hα-helixtrans-66.8-37.9-177.849.60000113.6G637 A641 Y642 E643G637-T639 PolarHBondContact O-N 3.42Å; T639-A641 VanDerWaalsContact C-N 3.26Å; T639-A641 PolarHBondContact O-N 3.26Å; T639-Y642 WeakPolarHBondContact O-CB 3.41Å; T639-Y642 PolarHBondContact O-N 3.34Å; T639-E643 PolarHBondContact O-N 3.45Å; T639-E643 VanDerWaalsContact O-N 3.15Å
640N93.7Very high95.9Very high16 Ų1645.4 Ų45.49%0.08623%0.229CC..Hα-helixtrans-61.9-39.3175.5-63.9-37.5000111D440 S443 L444 R482 N638 T644D440-N640 PolarHBondContact OD1-ND2 3.34Å; S443-N640 CarbonylContact O-C 3.53Å; L444-N640 HydrophobicContact CD2-CB 3.82Å; L444-N640 HydrophobicContact CG-CB 4.19Å; R482-N640 PolarHBondContact NE-OD1 2.98Å; R482-N640 PolarHBondContact NH1-OD1 3.04Å; R482-N640 PolarHBondContact NH2-OD1 2.82Å; N638-N640 WeakPolarHBondContact OD1-CA 3.41Å; N638-N640 VanDerWaalsContact OD1-CB 3.28Å; N638-N640 WeakPolarHBondContact OD1-CB 3.25Å; N638-N640 PolarHBondContact OD1-N 2.98Å; N640-T644 WeakPolarHBondContact O-CB 3.31Å; N640-T644 PolarHBondContact O-N 3.33Å; N640-T644 VanDerWaalsContact O-N 3.11Å; N640-T644 PolarHBondContact O-OG1 2.9Å
641A96.1Very high95.7Very high0 Ų051.9 Ų51.90%026%0.259CS..Hα-helixtrans-71.2-36.5177.700000112.4S443 V630 R633 C634 N638 T639 T644 I645S443-A641 WeakPolarHBondContact O-CA 3.44Å; S443-A641 PolarHBondContact O-N 3.44Å; V630-A641 HydrophobicContact CG1-CB 4.15Å; V630-A641 WeakPolarHBondContact O-CB 3.27Å; R633-A641 HydrophobicContact CB-CB 3.72Å; C634-A641 HydrophobicContact CB-CB 3.94Å; C634-A641 VanDerWaalsContact N-CB 3.31Å; N638-A641 HydrophobicContact CB-CB 4.05Å; N638-A641 PolarHBondContact O-N 2.96Å; N638-A641 PolarHBondContact OD1-N 3.37Å; N638-A641 VanDerWaalsContact OD1-N 3.16Å; T639-A641 VanDerWaalsContact C-N 3.26Å; T639-A641 PolarHBondContact O-N 3.26Å; A641-T644 PolarHBondContact O-N 2.93Å; A641-I645 WeakPolarHBondContact O-CG2 3.25Å; A641-I645 PolarHBondContact O-N 2.84Å
642Y96.4Very high95.5Very high90 Ų9053.2 Ų53.235%0.35326%0.263SS..Hα-helixtrans-56.4-55173.1-172.5-74.5000111.8C634 N638 T639 T644 Q646 M659 P660C634-Y642 VanDerWaalsContact SG-CA 3.54Å; N638-Y642 PolarHBondContact O-N 2.84Å; T639-Y642 WeakPolarHBondContact O-CB 3.41Å; T639-Y642 PolarHBondContact O-N 3.34Å; Y642-T644 VanDerWaalsContact C-N 3.26Å; Y642-T644 PolarHBondContact O-N 3.29Å; Y642-Q646 VanDerWaalsContact O-CB 3.3Å; Y642-Q646 WeakPolarHBondContact O-CB 3.35Å; Y642-Q646 PolarHBondContact O-N 3.32Å; Y642-M659 HydrophobicContact CD1-CE 3.91Å; Y642-M659 HydrophobicContact CD2-CE 3.54Å; Y642-M659 HydrophobicContact CE1-CE 3.78Å; Y642-M659 HydrophobicContact CE2-CB 4.43Å; Y642-M659 HydrophobicContact CE2-CE 3.44Å; Y642-M659 VanDerWaalsContact CE2-CE 3.44Å; Y642-M659 HydrophobicContact CG-CE 3.77Å; Y642-P660 HydrophobicContact CD2-CG 4.29Å
643E95.1Very high95.3Very high85 Ų8557 Ų5740%0.39730%0.295SS..Hα-helixtrans-62.5-35.6179.1-67.5173.5-175.200112.1R482 T639 R647R482-E643 IonicContact CZ-OE2 3.62Å; R482-E643 IonicContact NH1-OE2 2.88Å; R482-E643 PolarHBondContact NH1-OE2 2.83Å; R482-E643 IonicContact NH2-OE2 2.9Å; R482-E643 PolarHBondContact NH2-OE2 3.3Å; T639-E643 PolarHBondContact O-N 3.45Å; T639-E643 VanDerWaalsContact O-N 3.15Å; E643-R647 WeakPolarHBondContact O-CG 3.36Å; E643-R647 PolarHBondContact O-N 2.93Å; E643-R647 PolarHBondContact O-NE 3.17Å
644T96.1Very high95.2Very high15 Ų1565.3 Ų65.39%0.09233%0.334CS..Hα-helixtrans-70.4-51.4-179-58.30000111.1V630 N640 A641 Y642 Q646 R647 T648V630-T644 HydrophobicContact CG1-CG2 3.83Å; V630-T644 HydrophobicContact CG2-CG2 4.5Å; N640-T644 WeakPolarHBondContact O-CB 3.31Å; N640-T644 PolarHBondContact O-N 3.33Å; N640-T644 VanDerWaalsContact O-N 3.11Å; N640-T644 PolarHBondContact O-OG1 2.9Å; A641-T644 PolarHBondContact O-N 2.93Å; Y642-T644 VanDerWaalsContact C-N 3.26Å; Y642-T644 PolarHBondContact O-N 3.29Å; T644-Q646 VanDerWaalsContact C-N 3.31Å; T644-Q646 PolarHBondContact O-N 3.23Å; T644-R647 PolarHBondContact O-N 2.84Å; T644-T648 PolarHBondContact O-N 3.02Å; T644-T648 PolarHBondContact O-OG1 3.2Å; T644-T648 VanDerWaalsContact O-OG1 3.06Å
645I97.5Very high95.2Very high0 Ų067.2 Ų67.20%034%0.344CS..Hα-helixtrans-68.2-32.5-178-159.460.7000112.3V630 A631 C634 A641 T648 M649 L655 V657 M659V630-I645 HydrophobicContact CB-CD1 4.5Å; V630-I645 HydrophobicContact CG1-CB 3.94Å; V630-I645 HydrophobicContact CG1-CD1 4.4Å; A631-I645 HydrophobicContact CB-CD1 4.1Å; A631-I645 HydrophobicContact CB-CG1 4.11Å; C634-I645 HydrophobicContact CB-CG2 3.89Å; A641-I645 WeakPolarHBondContact O-CG2 3.25Å; A641-I645 PolarHBondContact O-N 2.84Å; I645-T648 PolarHBondContact O-N 3.01Å; I645-M649 WeakPolarHBondContact O-CG 3.41Å; I645-M649 PolarHBondContact O-N 3.26Å; I645-L655 HydrophobicContact CD1-CD2 4.05Å; I645-V657 HydrophobicContact CD1-CG1 4.44Å; I645-V657 HydrophobicContact CG1-CG1 4.24Å; I645-V657 HydrophobicContact CG1-CG2 3.54Å; I645-V657 HydrophobicContact CG2-CG2 4.22Å; I645-M659 HydrophobicContact CG2-CE 3.91Å; I645-M659 HydrophobicContact CG2-SD 3.81Å
646Q96.6Very high95.2Very high77 Ų7771 Ų7136%0.3636%0.358SS..Hα-helixtrans-59.2-51.3173.7-178.4-179-13.900110.9Y642 T644 T648 M649 E650 M659Y642-Q646 VanDerWaalsContact O-CB 3.3Å; Y642-Q646 WeakPolarHBondContact O-CB 3.35Å; Y642-Q646 PolarHBondContact O-N 3.32Å; T644-Q646 VanDerWaalsContact C-N 3.31Å; T644-Q646 PolarHBondContact O-N 3.23Å; Q646-T648 VanDerWaalsContact C-N 3.31Å; Q646-T648 PolarHBondContact O-N 2.95Å; Q646-M649 PolarHBondContact O-N 3.25Å; Q646-M649 VanDerWaalsContact O-N 3.16Å; Q646-E650 PolarHBondContact NE2-OE1 3.43Å; Q646-E650 WeakPolarHBondContact O-CG 3.48Å; Q646-E650 PolarHBondContact O-N 2.73Å; Q646-M659 HydrophobicContact CB-CE 4.33Å
647R94.3Very high95.3Very high87 Ų8772.5 Ų72.533%0.32837%0.366SS..Hα-helixtrans-60.9-40176.3-70.8-178.8-61.5-163.24112.1E643 T644 M649 E650 E651E643-R647 WeakPolarHBondContact O-CG 3.36Å; E643-R647 PolarHBondContact O-N 2.93Å; E643-R647 PolarHBondContact O-NE 3.17Å; T644-R647 PolarHBondContact O-N 2.84Å; R647-M649 VanDerWaalsContact C-N 3.3Å; R647-M649 PolarHBondContact O-N 3.36Å; R647-E650 WeakPolarHBondContact O-CB 3.41Å; R647-E650 PolarHBondContact O-N 2.8Å; R647-E650 VanDerWaalsContact O-N 3.15Å; R647-E651 PolarHBondContact O-N 3.19Å
648T95.1Very high95.5Very high12 Ų1274.7 Ų74.77%0.07437%0.368CS..Hα-helixtrans-61.8-37.8176.6-53.20000112.1T644 I645 Q646 E651 N652 L655T644-T648 PolarHBondContact O-N 3.02Å; T644-T648 PolarHBondContact O-OG1 3.2Å; T644-T648 VanDerWaalsContact O-OG1 3.06Å; I645-T648 PolarHBondContact O-N 3.01Å; Q646-T648 VanDerWaalsContact C-N 3.31Å; Q646-T648 PolarHBondContact O-N 2.95Å; T648-E651 PolarHBondContact O-N 3.04Å; T648-N652 WeakPolarHBondContact O-CB 3.16Å; T648-N652 PolarHBondContact O-N 3.08Å; T648-L655 HydrophobicContact CG2-CD2 3.49Å; T648-L655 VanDerWaalsContact CG2-CD2 3.49Å
649M96.9Very high95.7Very high41 Ų4175.5 Ų75.520%0.20237%0.372CS..Hα-helixtrans-68.9-34174-70.3-169.9-69.600112.7I645 Q646 R647 N652 L655 V657 M659I645-M649 WeakPolarHBondContact O-CG 3.41Å; I645-M649 PolarHBondContact O-N 3.26Å; Q646-M649 PolarHBondContact O-N 3.25Å; Q646-M649 VanDerWaalsContact O-N 3.16Å; R647-M649 VanDerWaalsContact C-N 3.3Å; R647-M649 PolarHBondContact O-N 3.36Å; M649-N652 CarbonylContact O-C 3.34Å; M649-N652 PolarHBondContact O-N 3.08Å; M649-N652 VanDerWaalsContact O-O 3.13Å; M649-L655 HydrophobicContact CG-CB 4.49Å; M649-L655 HydrophobicContact CG-CD2 4.18Å; M649-L655 HydrophobicContact CG-CG 4.02Å; M649-L655 WeakPolarHBondContact CG-O 3.33Å; M649-V657 HydrophobicContact CE-CG2 3.83Å; M649-V657 HydrophobicContact CG-CG2 4.45Å; M649-V657 HydrophobicContact SD-CB 4.32Å; M649-V657 HydrophobicContact SD-CG2 3.59Å; M649-V657 VanDerWaalsContact SD-CG2 3.59Å; M649-V657 PolarHBondContact SD-N 3.28Å; M649-M659 HydrophobicContact CE-CE 4.49Å; M649-M659 HydrophobicContact CE-CG 3.98Å; M649-M659 HydrophobicContact CE-SD 3.44Å; M649-M659 WeakPolarHBondContact CE-SD 3.28Å
650E95.4Very high95.9Very high132 Ų13271.9 Ų71.962%0.61735%0.35SS*.Hα-helixtrans-66.5-38.1174.4-68.9165.9-174.300111.6Q646 R647Q646-E650 PolarHBondContact NE2-OE1 3.43Å; Q646-E650 WeakPolarHBondContact O-CG 3.48Å; Q646-E650 PolarHBondContact O-N 2.73Å; R647-E650 WeakPolarHBondContact O-CB 3.41Å; R647-E650 PolarHBondContact O-N 2.8Å; R647-E650 VanDerWaalsContact O-N 3.15Å
651E92.4Very high95.9Very high138 Ų13880.6 Ų80.665%0.64539%0.387SS*.Hα-helixtrans-78.1-22176.8-67.9-174.3162.200113.3K516 R647 T648K516-E651 IonicContact NZ-OE1 2.69Å; R647-E651 PolarHBondContact O-N 3.19Å; T648-E651 PolarHBondContact O-N 3.04Å
652N93.9Very high95.7Very high51 Ų5185 Ų8527%0.27342%0.416SS..  trans-133.698.8-178.4-177.5-4.8000112.1T648 M649 Q654 L655T648-N652 WeakPolarHBondContact O-CB 3.16Å; T648-N652 PolarHBondContact O-N 3.08Å; M649-N652 CarbonylContact O-C 3.34Å; M649-N652 PolarHBondContact O-N 3.08Å; M649-N652 VanDerWaalsContact O-O 3.13Å; N652-Q654 PolarHBondContact O-N 3.12Å; N652-Q654 WeakPolarHBondContact OD1-CB 3.49Å; N652-Q654 PolarHBondContact OD1-N 3.12Å; N652-L655 HydrophobicContact CB-CB 4.27Å; N652-L655 PolarHBondContact O-N 3.44Å
653S93.9Very high95.5Very high113 Ų11384.3 Ų84.379%0.7942%0.421SS*.THydrogen-bonded Turntrans-62.8-14.8-178.965.40000115.2
654Q95.5Very high95.4Very high177 Ų17788.4 Ų88.483%0.82744%0.44SS*.THydrogen-bonded Turntrans-86.6-17.5175.3-61.2-169.7-46.900112.7N652N652-Q654 PolarHBondContact O-N 3.12Å; N652-Q654 WeakPolarHBondContact OD1-CB 3.49Å; N652-Q654 PolarHBondContact OD1-N 3.12Å
655L96.9Very high95.2Very high41 Ų4190.6 Ų90.622%0.21545%0.451CS..  trans-86.7119.5175-178.565.5000109.2I645 T648 M649 N652 V657I645-L655 HydrophobicContact CD1-CD2 4.05Å; T648-L655 HydrophobicContact CG2-CD2 3.49Å; T648-L655 VanDerWaalsContact CG2-CD2 3.49Å; M649-L655 HydrophobicContact CG-CB 4.49Å; M649-L655 HydrophobicContact CG-CD2 4.18Å; M649-L655 HydrophobicContact CG-CG 4.02Å; M649-L655 WeakPolarHBondContact CG-O 3.33Å; N652-L655 HydrophobicContact CB-CB 4.27Å; N652-L655 PolarHBondContact O-N 3.44Å; L655-V657 HydrophobicContact CD1-CG1 3.95Å; L655-V657 HydrophobicContact CG-CG1 4.32Å
656R97.7Very high95Very high225 Ų22596.4 Ų96.485%0.84948%0.478SS*.  trans-135.3116.1173-63.1-178.768.5-174.71108.2
657V97.9Very high94.8Very high41 Ų4198.1 Ų98.125%0.24849%0.486CS..  trans-114.7159.8178.1-55.30000110.6A631 I645 M649 L655 M659A631-V657 HydrophobicContact CB-CB 4.35Å; A631-V657 HydrophobicContact CB-CG1 3.94Å; I645-V657 HydrophobicContact CD1-CG1 4.44Å; I645-V657 HydrophobicContact CG1-CG1 4.24Å; I645-V657 HydrophobicContact CG1-CG2 3.54Å; I645-V657 HydrophobicContact CG2-CG2 4.22Å; M649-V657 HydrophobicContact CE-CG2 3.83Å; M649-V657 HydrophobicContact CG-CG2 4.45Å; M649-V657 HydrophobicContact SD-CB 4.32Å; M649-V657 HydrophobicContact SD-CG2 3.59Å; M649-V657 VanDerWaalsContact SD-CG2 3.59Å; M649-V657 PolarHBondContact SD-N 3.28Å; L655-V657 HydrophobicContact CD1-CG1 3.95Å; L655-V657 HydrophobicContact CG-CG1 4.32Å; V657-M659 HydrophobicContact CG2-SD 3.89Å; V657-M659 PolarHBondContact O-N 2.8Å
658T98.2Very high94.9Very high104 Ų10497.4 Ų97.464%0.63849%0.491SS*.PPolyproline II helixtrans-75.1121.1172.4-50.50000109.6W635W635-T658 HydrophobicContact CE3-CG2 4.1Å; W635-T658 HydrophobicContact CH2-CG2 4.34Å; W635-T658 HydrophobicContact CZ3-CG2 3.54Å
659M97.9Very high94.9Very high40 Ų40100.3 Ų100.320%0.19751%0.506CS..PPolyproline II helixtrans-91132.3174.4-59.5-58.2-70.400110Y642 I645 Q646 M649 V657Y642-M659 HydrophobicContact CD1-CE 3.91Å; Y642-M659 HydrophobicContact CD2-CE 3.54Å; Y642-M659 HydrophobicContact CE1-CE 3.78Å; Y642-M659 HydrophobicContact CE2-CB 4.43Å; Y642-M659 HydrophobicContact CE2-CE 3.44Å; Y642-M659 VanDerWaalsContact CE2-CE 3.44Å; Y642-M659 HydrophobicContact CG-CE 3.77Å; I645-M659 HydrophobicContact CG2-CE 3.91Å; I645-M659 HydrophobicContact CG2-SD 3.81Å; Q646-M659 HydrophobicContact CB-CE 4.33Å; M649-M659 HydrophobicContact CE-CE 4.49Å; M649-M659 HydrophobicContact CE-CG 3.98Å; M649-M659 HydrophobicContact CE-SD 3.44Å; M649-M659 WeakPolarHBondContact CE-SD 3.28Å; V657-M659 HydrophobicContact CG2-SD 3.89Å; V657-M659 PolarHBondContact O-N 2.8Å
660P96.2Very high94.7Very high25 Ų25101.9 Ų101.916%0.16252%0.515CS..PPolyproline II helixtrans-75.4145.5178.632.1-35.9000111.4C634 W635 Y642C634-P660 WeakPolarHBondContact O-CG 3.49Å; C634-P660 VanDerWaalsContact SG-CD 3.54Å; W635-P660 HydrophobicContact CE3-CB 4.14Å; W635-P660 HydrophobicContact CZ3-CB 4.39Å; Y642-P660 HydrophobicContact CD2-CG 4.29Å
661F94.4Very high94.7Very high198 Ų198102.2 Ų102.287%0.86851%0.511SS*.  trans-102.8114169.3-69.6-84.6000109
662P90.9Very high94.8Very high92 Ų9299.5 Ų99.560%0.59751%0.512SS*.  trans-70.8142.1178.326-29.7000110.9Q664P662-Q664 PolarHBondContact O-N 3.21Å; P662-Q664 PolarHBondContact O-NE2 3.34Å
663V93.2Very high94.8Very high76 Ų76104.3 Ų104.346%0.46154%0.537SS..  trans-62.5121.7170.1179.10000108.1D665 L669V663-D665 WeakPolarHBondContact CG1-O 3.44Å; V663-L669 HydrophobicContact CG1-CD2 4.43Å; V663-L669 HydrophobicContact CG1-CG 4.35Å; V663-L669 HydrophobicContact CG2-CD2 4.48Å
664Q91.9Very high94.5Very high172 Ų172106.2 Ų106.280%0.80453%0.533SS*.SBendtrans-84.9-29.2-176.3-61.4-64-49.700112.9P662P662-Q664 PolarHBondContact O-N 3.21Å; P662-Q664 PolarHBondContact O-NE2 3.34Å
665D92.8Very high92.9Very high60 Ų60104.3 Ų104.332%0.32156%0.562SS.*  trans-130.5103.9-179.5173.125.4000109V663 H667 V668 R671V663-D665 WeakPolarHBondContact CG1-O 3.44Å; D665-H667 PolarHBondContact O-N 3.21Å; D665-H667 VanDerWaalsContact OD1-CB 3.26Å; D665-H667 WeakPolarHBondContact OD1-CB 3.43Å; D665-H667 IonicContact OD1-CD2 3.9Å; D665-H667 PolarHBondContact OD1-CD2 3.33Å; D665-H667 VanDerWaalsContact OD1-CD2 3.27Å; D665-H667 IonicContact OD1-CG 2.89Å; D665-H667 PolarHBondContact OD1-N 3.27Å; D665-V668 HydrophobicContact CB-CG2 4.03Å; D665-V668 VanDerWaalsContact O-CB 3.29Å; D665-V668 WeakPolarHBondContact O-CB 3.47Å; D665-V668 WeakPolarHBondContact O-CG2 3.24Å; D665-V668 PolarHBondContact O-N 2.99Å; D665-R671 IonicContact OD2-CZ 3.47Å; D665-R671 IonicContact OD2-NH1 3.73Å; D665-R671 IonicContact OD2-NH2 3.95Å; D665-R671 PolarHBondContact OD2-NH2 3.49Å
666E91.9Very high92.7Very high122 Ų122107.5 Ų107.557%0.5758%0.579SS**THydrogen-bonded Turntrans-59.6-26177.8-72.8-68.6165.400112.3V668 L669 D670E666-V668 PolarHBondContact O-N 2.77Å; E666-V668 VanDerWaalsContact O-N 3.15Å; E666-L669 WeakPolarHBondContact O-CA 3.49Å; E666-L669 VanDerWaalsContact O-CB 3.3Å; E666-L669 WeakPolarHBondContact O-CB 3.22Å; E666-L669 PolarHBondContact O-N 2.77Å; E666-L669 WeakPolarHBondContact OE2-CD1 3.46Å; E666-D670 PolarHBondContact O-N 3.43Å
667H93.6Very high92.5Very high113 Ų113101.3 Ų101.352%0.52357%0.565SS.*Hα-helixtrans-65.8-18.5176.2-60.5-58000113D665 L669 D670 R671D665-H667 PolarHBondContact O-N 3.21Å; D665-H667 VanDerWaalsContact OD1-CB 3.26Å; D665-H667 WeakPolarHBondContact OD1-CB 3.43Å; D665-H667 IonicContact OD1-CD2 3.9Å; D665-H667 PolarHBondContact OD1-CD2 3.33Å; D665-H667 VanDerWaalsContact OD1-CD2 3.27Å; D665-H667 IonicContact OD1-CG 2.89Å; D665-H667 PolarHBondContact OD1-N 3.27Å; H667-L669 PolarHBondContact O-N 3.19Å; H667-D670 IonicContact ND1-OD2 3.16Å; H667-D670 PolarHBondContact ND1-OD2 3.24Å; H667-D670 PolarHBondContact O-N 3.17Å; H667-R671 WeakPolarHBondContact O-CB 3.41Å; H667-R671 VanDerWaalsContact O-CG 3.25Å; H667-R671 WeakPolarHBondContact O-CG 3.18Å; H667-R671 PolarHBondContact O-N 2.86Å; H667-R671 PolarHBondContact O-NE 3.15Å
668V95.7Very high92.2Very high72 Ų72104.7 Ų104.744%0.43658%0.582SS.*Hα-helixtrans-59.6-38.9168.9175.50000110.1D665 E666 A672D665-V668 HydrophobicContact CB-CG2 4.03Å; D665-V668 VanDerWaalsContact O-CB 3.29Å; D665-V668 WeakPolarHBondContact O-CB 3.47Å; D665-V668 WeakPolarHBondContact O-CG2 3.24Å; D665-V668 PolarHBondContact O-N 2.99Å; E666-V668 PolarHBondContact O-N 2.77Å; E666-V668 VanDerWaalsContact O-N 3.15Å; V668-A672 VanDerWaalsContact O-CB 3.31Å; V668-A672 WeakPolarHBondContact O-CB 3.38Å; V668-A672 PolarHBondContact O-N 3.38Å; V668-A672 VanDerWaalsContact O-N 3.08Å
669L95.2Very high91.8Very high73 Ų73104.7 Ų104.738%0.38258%0.579SS.*Hα-helixtrans-71-47.1178.5-51.5-171.4000110.7V663 E666 H667 R671 A672 L673V663-L669 HydrophobicContact CG1-CD2 4.43Å; V663-L669 HydrophobicContact CG1-CG 4.35Å; V663-L669 HydrophobicContact CG2-CD2 4.48Å; E666-L669 WeakPolarHBondContact O-CA 3.49Å; E666-L669 VanDerWaalsContact O-CB 3.3Å; E666-L669 WeakPolarHBondContact O-CB 3.22Å; E666-L669 PolarHBondContact O-N 2.77Å; E666-L669 WeakPolarHBondContact OE2-CD1 3.46Å; H667-L669 PolarHBondContact O-N 3.19Å; L669-R671 VanDerWaalsContact C-N 3.34Å; L669-R671 PolarHBondContact O-N 2.79Å; L669-A672 PolarHBondContact O-N 2.92Å; L669-A672 VanDerWaalsContact O-N 3.15Å; L669-L673 WeakPolarHBondContact O-CG 3.39Å; L669-L673 PolarHBondContact O-N 3.45Å
670D93.6Very high91.4Very high75 Ų75108.8 Ų108.840%0.40160%0.603SS.*Hα-helixtrans-55.6-49.7177-66.8-31.8000111.2E666 H667 A672 L673 Q674E666-D670 PolarHBondContact O-N 3.43Å; H667-D670 IonicContact ND1-OD2 3.16Å; H667-D670 PolarHBondContact ND1-OD2 3.24Å; H667-D670 PolarHBondContact O-N 3.17Å; D670-A672 VanDerWaalsContact C-N 3.32Å; D670-A672 PolarHBondContact O-N 3.1Å; D670-L673 PolarHBondContact O-N 2.81Å; D670-Q674 VanDerWaalsContact O-CB 3.3Å; D670-Q674 WeakPolarHBondContact O-CB 3.35Å; D670-Q674 WeakPolarHBondContact O-CG 3.43Å; D670-Q674 PolarHBondContact O-N 2.89Å
671R95.4Very high91.1Very high139 Ų139114.3 Ų114.353%0.52563%0.632SS.*Hα-helixtrans-61-40.4178.3-72.8-174.6-61.1-94.33112D665 H667 L669 L673D665-R671 IonicContact OD2-CZ 3.47Å; D665-R671 IonicContact OD2-NH1 3.73Å; D665-R671 IonicContact OD2-NH2 3.95Å; D665-R671 PolarHBondContact OD2-NH2 3.49Å; H667-R671 WeakPolarHBondContact O-CB 3.41Å; H667-R671 VanDerWaalsContact O-CG 3.25Å; H667-R671 WeakPolarHBondContact O-CG 3.18Å; H667-R671 PolarHBondContact O-N 2.86Å; H667-R671 PolarHBondContact O-NE 3.15Å; L669-R671 VanDerWaalsContact C-N 3.34Å; L669-R671 PolarHBondContact O-N 2.79Å; R671-L673 VanDerWaalsContact C-N 3.31Å; R671-L673 PolarHBondContact O-N 3.43Å
672A94Very high90.9Very high81 Ų81108.4 Ų108.467%0.66962%0.616SS**Hα-helixtrans-68-30.9179.200000112.7V668 L669 D670V668-A672 VanDerWaalsContact O-CB 3.31Å; V668-A672 WeakPolarHBondContact O-CB 3.38Å; V668-A672 PolarHBondContact O-N 3.38Å; V668-A672 VanDerWaalsContact O-N 3.08Å; L669-A672 PolarHBondContact O-N 2.92Å; L669-A672 VanDerWaalsContact O-N 3.15Å; D670-A672 VanDerWaalsContact C-N 3.32Å; D670-A672 PolarHBondContact O-N 3.1Å
673L93.9Very high90.9Very high152 Ų152109.6 Ų109.680%0.79662%0.617SS**Hα-helixtrans-88-21.7179.2-66.8174.4000113.5L669 D670 R671L669-L673 WeakPolarHBondContact O-CG 3.39Å; L669-L673 PolarHBondContact O-N 3.45Å; D670-L673 PolarHBondContact O-N 2.81Å; R671-L673 VanDerWaalsContact C-N 3.31Å; R671-L673 PolarHBondContact O-N 3.43Å
674Q87.4Confident90.7Very high152 Ų152112.4 Ų112.471%0.7163%0.63SS**Hα-helixtrans-79.5-16.2-177.5-79173.510.100114.7D670D670-Q674 VanDerWaalsContact O-CB 3.3Å; D670-Q674 WeakPolarHBondContact O-CB 3.35Å; D670-Q674 WeakPolarHBondContact O-CG 3.43Å; D670-Q674 PolarHBondContact O-N 2.89Å
675G62.7Low90.6Very high138 Ų138107 Ų107100%1.42361%0.614SS**  trans64.10172.100000114.9

Retrieved 675 of 675 residues in 265.1 ms (Link to these results)