A0A087XGR4_POEFO Loading...

Sialin

Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.

AlphaFold DB , UniProt , Accession A0A087XGR4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 493 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.9	Very low	32.6	Very low	238 Å²	238	144.3 Å²	144.3	100%	1.172	69%	0.693	S	S	*	*				0	46.4	0	-165.3	157.2	172.2	0	0	108.8
2	E	34.3	Very low	32.7	Very low	189 Å²	189	144.9 Å²	144.9	88%	0.883	70%	0.695	S	S	*	*			trans	-130.9	22.8	-165.1	-77.6	177.9	144.7	0	0	112
3	R	28.8	Very low	33.2	Very low	227 Å²	227	146.8 Å²	146.8	86%	0.857	70%	0.702	S	S	*	*	S	Bend	trans	-117.2	5.6	-179.4	-107.8	-174.9	-165.7	-176.6	4.5	114.3
4	Y	28.9	Very low	33.2	Very low	214 Å²	214	147.4 Å²	147.4	84%	0.839	70%	0.704	S	S	*	*	S	Bend	trans	-104	-18.5	-178.7	-117.1	-91.4	0	0	0	113.7
5	D	33.4	Very low	33	Very low	129 Å²	129	149.5 Å²	149.5	69%	0.69	70%	0.702	S	S	*	*	H	α-helix	trans	-87.5	-21.4	-178	-73.4	-30.5	0	0	0	114.3	D7 E9	D5-D7 PolarHBondContact O-N 3.27Å; D5-E9 PolarHBondContact O-N 3.14Å
6	S	34.5	Very low	33.2	Very low	62 Å²	62	146.6 Å²	146.6	43%	0.434	70%	0.7	S	S	.	*	H	α-helix	trans	-77.4	-20.9	-178.7	79	0	0	0	0	114.5
7	D	31.6	Very low	34.1	Very low	97 Å²	97	148.5 Å²	148.5	52%	0.519	71%	0.714	S	S	.	*	H	α-helix	trans	-91.8	-26	179.7	-70.7	-16.5	0	0	0	111.3	D5 K10 D11	D5-D7 PolarHBondContact O-N 3.27Å; D7-K10 PolarHBondContact O-N 3.28Å; D7-D11 PolarHBondContact O-N 3.27Å; D7-D11 VanDerWaalsContact O-N 3.11Å
8	A	32.8	Very low	34.5	Very low	54 Å²	54	145.7 Å²	145.7	45%	0.446	70%	0.703	S	S	.	*	H	α-helix	trans	-67.6	-39.4	171.5	0	0	0	0	0	112.5	K10 D11 E12	A8-K10 VanDerWaalsContact C-N 3.34Å; A8-K10 PolarHBondContact O-N 2.94Å; A8-D11 PolarHBondContact O-N 2.9Å; A8-E12 PolarHBondContact O-N 2.99Å
9	E	34.9	Very low	34.2	Very low	140 Å²	140	147.1 Å²	147.1	65%	0.654	71%	0.708	S	S	*	*	H	α-helix	trans	-67.8	-30.7	175	-86.1	-171	144.7	0	0	113.2	D5	D5-E9 PolarHBondContact O-N 3.14Å
10	K	32.8	Very low	34.1	Very low	134 Å²	134	151.6 Å²	151.6	58%	0.583	72%	0.717	S	S	*	*	H	α-helix	trans	-75.2	-32.9	175.8	-79.4	177.8	-178.2	166.7	0	112.6	D7 A8	D7-K10 PolarHBondContact O-N 3.28Å; A8-K10 VanDerWaalsContact C-N 3.34Å; A8-K10 PolarHBondContact O-N 2.94Å
11	D	30.3	Very low	34.2	Very low	103 Å²	103	153 Å²	153	55%	0.551	72%	0.715	S	S	*	*	H	α-helix	trans	-79.1	-25.4	175.7	-89.4	-4.3	0	0	0	113.1	D7 A8 Q13 Q14	D7-D11 PolarHBondContact O-N 3.27Å; D7-D11 VanDerWaalsContact O-N 3.11Å; A8-D11 PolarHBondContact O-N 2.9Å; D11-Q13 VanDerWaalsContact C-N 3.31Å; D11-Q13 PolarHBondContact O-N 3.11Å; D11-Q14 PolarHBondContact O-N 2.83Å
12	E	33.1	Very low	34	Very low	152 Å²	152	150.4 Å²	150.4	71%	0.71	70%	0.7	S	S	*	*	H	α-helix	trans	-68.1	-28.3	172.8	-90.6	-166.5	144.7	0	0	113.4	A8 Q14	A8-E12 PolarHBondContact O-N 2.99Å; E12-Q14 VanDerWaalsContact C-N 3.32Å; E12-Q14 PolarHBondContact O-N 3.14Å
13	Q	39	Very low	34	Very low	170 Å²	170	148.6 Å²	148.6	79%	0.794	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.2	-9.8	176.8	-75.5	174.1	-15.8	0	0	113.8	D11	D11-Q13 VanDerWaalsContact C-N 3.31Å; D11-Q13 PolarHBondContact O-N 3.11Å
14	Q	34.1	Very low	34.6	Very low	154 Å²	154	145 Å²	145	72%	0.72	70%	0.695	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.4	-5.3	-179.6	-73.3	-172.6	1.1	0	0	114.6	D11 E12	D11-Q14 PolarHBondContact O-N 2.83Å; E12-Q14 VanDerWaalsContact C-N 3.32Å; E12-Q14 PolarHBondContact O-N 3.14Å
15	R	30.4	Very low	35.4	Very low	179 Å²	179	144.3 Å²	144.3	68%	0.675	70%	0.696	S	S	*	*	S	Bend	trans	-85	136.8	-179.6	-67.7	-175	-179.5	-167.6	1	111.9	L17	R15-L17 PolarHBondContact O-N 3.44Å
16	P	36.2	Very low	36.5	Very low	103 Å²	103	141.9 Å²	141.9	67%	0.669	68%	0.682	S	S	*	*			trans	-58	138.3	170.7	23.3	-30.6	0	0	0	109.8	L18	P16-L18 PolarHBondContact O-N 2.79Å
17	L	48.1	Very low	37.7	Very low	179 Å²	179	147.1 Å²	147.1	94%	0.937	70%	0.7	S	S	*	*	T	Hydrogen-bonded Turn	trans	-54.4	10.3	-171.6	-73.1	160.7	0	0	0	117.1	R15	R15-L17 PolarHBondContact O-N 3.44Å
18	L	41.1	Very low	39.4	Very low	98 Å²	98	150.6 Å²	150.6	51%	0.513	71%	0.706	S	S	.	*	T	Hydrogen-bonded Turn	trans	-87.4	-9.9	-172.5	-81.8	163	0	0	0	115.2	P16 R21	P16-L18 PolarHBondContact O-N 2.79Å; L18-R21 WeakPolarHBondContact O-CB 3.43Å
19	H	29	Very low	41.4	Very low	173 Å²	173	148.4 Å²	148.4	80%	0.801	69%	0.688	S	S	*	*	S	Bend	trans	-94.6	-3.2	-177.9	-121.4	38.7	0	0	0	115.9	R21	H19-R21 PolarHBondContact O-N 3.08Å; H19-R21 VanDerWaalsContact O-N 3.13Å
20	R	31.8	Very low	43.1	Very low	236 Å²	236	145.4 Å²	145.4	89%	0.891	68%	0.68	S	S	*	*	S	Bend	trans	-84.3	31.3	169.3	-152	179.4	-173.5	170.1	3.6	112.6	Q22	R20-Q22 PolarHBondContact O-N 3.48Å
21	R	36.8	Very low	44.8	Very low	181 Å²	181	141.9 Å²	141.9	68%	0.683	68%	0.676	S	S	*	*			trans	-103.8	66.6	-166	-155.8	-176	-155	-170.7	7.3	110.6	L18 H19	L18-R21 WeakPolarHBondContact O-CB 3.43Å; H19-R21 PolarHBondContact O-N 3.08Å; H19-R21 VanDerWaalsContact O-N 3.13Å
22	Q	32.8	Very low	46.4	Very low	184 Å²	184	141.9 Å²	141.9	86%	0.86	68%	0.683	S	S	*	*	S	Bend	trans	-144.9	-12.7	161.1	-127.5	145.7	-14.7	0	0	118.6	R20	R20-Q22 PolarHBondContact O-N 3.48Å
23	D	34.3	Very low	48.2	Very low	152 Å²	152	140.9 Å²	140.9	81%	0.813	69%	0.691	S	S	*	*	S	Bend	trans	-119	5.9	-176.3	-74.5	-29.2	0	0	0	118.4
24	D	41.6	Very low	50.4	Low	152 Å²	152	133.2 Å²	133.2	81%	0.813	66%	0.656	S	S	*	*			trans	-159	90.6	165.1	-92.8	-37.8	0	0	0	111.3	I26	D24-I26 VanDerWaalsContact C-N 3.27Å; D24-I26 PolarHBondContact O-N 3.29Å
25	K	44.3	Very low	53	Low	198 Å²	198	126.8 Å²	126.8	86%	0.861	63%	0.628	S	S	*	*			trans	-70.9	89.1	166.8	-85.8	179.4	-179.3	172.7	0	108.2	Q27	K25-Q27 PolarHBondContact O-N 3.19Å
26	I	57.8	Low	55.8	Low	79 Å²	79	118.3 Å²	118.3	41%	0.405	60%	0.596	S	S	.	*			trans	-55	107.5	169.3	-62.8	175.6	0	0	0	108.1	D24 R28 Y262	D24-I26 VanDerWaalsContact C-N 3.27Å; D24-I26 PolarHBondContact O-N 3.29Å; I26-R28 PolarHBondContact O-N 2.71Å; I26-Y262 HydrophobicContact CG2-CD2 3.35Å; I26-Y262 HydrophobicContact CG2-CE2 3.59Å
27	Q	59.5	Low	58.4	Low	172 Å²	172	115.4 Å²	115.4	80%	0.804	57%	0.572	S	S	*	*	P	Polyproline II helix	trans	-69.1	119.8	-178.9	-163.1	168.2	5.3	0	0	108.9	K25 A29 Y262	K25-Q27 PolarHBondContact O-N 3.19Å; Q27-A29 PolarHBondContact O-N 2.84Å; Q27-Y262 VanDerWaalsContact O-CD2 3.3Å; Q27-Y262 WeakPolarHBondContact O-CD2 3.15Å
28	R	67.1	Low	60.5	Low	170 Å²	170	108.4 Å²	108.4	64%	0.642	54%	0.543	S	S	*	.	P	Polyproline II helix	trans	-65	123.9	-179.6	-74.2	-176.6	178	-175.5	-5.4	109.6	I26 Y262	I26-R28 PolarHBondContact O-N 2.71Å; R28-Y262 HydrophobicContact CG-CE2 4.46Å
29	A	73.6	Confident	63	Low	8 Å²	8	104.1 Å²	104.1	7%	0.066	52%	0.521	C	S	.	.	P	Polyproline II helix	trans	-73.7	141.2	174.6	0	0	0	0	0	111.2	Q27 R36 E259 Y262	Q27-A29 PolarHBondContact O-N 2.84Å; A29-R36 PolarHBondContact O-NH2 3.4Å; A29-R36 VanDerWaalsContact O-NH2 3.13Å; A29-E259 HydrophobicContact CB-CB 4.08Å; A29-E259 HydrophobicContact CB-CG 4.36Å; A29-Y262 HydrophobicContact CB-CD1 4.03Å; A29-Y262 HydrophobicContact CB-CG 4.12Å
30	P	72.4	Confident	66	Low	77 Å²	77	95.9 Å²	95.9	50%	0.5	48%	0.483	S	S	.	.	P	Polyproline II helix	trans	-63.3	149.3	-174.1	25.5	-33.9	0	0	0	112.4	S34	P30-S34 WeakPolarHBondContact O-CB 3.38Å
31	A	66.8	Low	69	Low	59 Å²	59	90.1 Å²	90.1	49%	0.488	47%	0.469	S	S	.	.	S	Bend	trans	-78.7	-25.8	179.6	0	0	0	0	0	113.3	Y37	A31-Y37 HydrophobicContact CB-CE2 4Å
32	C	64.1	Low	71.7	Confident	104 Å²	104	83.2 Å²	83.2	70%	0.703	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73	130.7	177.2	-169.4	0	0	0	0	110.3	S34	C32-S34 PolarHBondContact O-N 2.7Å
33	C	71.7	Confident	74.6	Confident	130 Å²	130	74.5 Å²	74.5	88%	0.878	41%	0.405	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.5	22.8	-178.1	-56.6	0	0	0	0	115.2
34	S	85.3	Confident	77.5	Confident	9 Å²	9	68 Å²	68	6%	0.063	37%	0.372	C	S	.	.			trans	-76.2	132.1	179.2	160.4	0	0	0	0	111.8	P30 C32 R36 Y37 G38 E259	P30-S34 WeakPolarHBondContact O-CB 3.38Å; C32-S34 PolarHBondContact O-N 2.7Å; S34-R36 VanDerWaalsContact C-N 3.28Å; S34-R36 PolarHBondContact O-N 2.78Å; S34-R36 VanDerWaalsContact OG-CG 3.25Å; S34-R36 WeakPolarHBondContact OG-CG 3.34Å; S34-R36 PolarHBondContact OG-N 3.12Å; S34-Y37 PolarHBondContact O-N 3.33Å; S34-G38 PolarHBondContact O-N 3.36Å; S34-G38 VanDerWaalsContact O-N 3.09Å; S34-E259 PolarHBondContact OG-OE1 2.95Å
35	S	88.2	Confident	80.1	Confident	19 Å²	19	64.7 Å²	64.7	13%	0.133	35%	0.348	C	S	.	.	H	α-helix	trans	-64.9	-33	179.7	-58.9	0	0	0	0	111.5	Y37 G38 L39 E259	S35-Y37 PolarHBondContact O-N 3.48Å; S35-G38 PolarHBondContact O-N 2.72Å; S35-L39 PolarHBondContact O-N 3.35Å; S35-E259 PolarHBondContact N-OE1 3.35Å; S35-E259 VanDerWaalsContact N-OE1 3.09Å; S35-E259 PolarHBondContact N-OE2 2.99Å
36	R	90.6	Very high	82.6	Confident	1 Å²	1	55.2 Å²	55.2	0%	0.004	31%	0.307	C	S	.	.	H	α-helix	trans	-66.4	-34.7	178	84.1	-148.4	180	-139.5	1	113.2	A29 S34 A40 W186 E191 L195 E259	A29-R36 PolarHBondContact O-NH2 3.4Å; A29-R36 VanDerWaalsContact O-NH2 3.13Å; S34-R36 VanDerWaalsContact C-N 3.28Å; S34-R36 PolarHBondContact O-N 2.78Å; S34-R36 VanDerWaalsContact OG-CG 3.25Å; S34-R36 WeakPolarHBondContact OG-CG 3.34Å; S34-R36 PolarHBondContact OG-N 3.12Å; R36-A40 PolarHBondContact O-N 3.1Å; R36-W186 HydrophobicContact CB-CE3 4.38Å; R36-E191 IonicContact CZ-OE1 2.72Å; R36-E191 IonicContact CZ-OE2 3.44Å; R36-E191 IonicContact NE-OE2 3.89Å; R36-E191 PolarHBondContact NE-OE2 3.18Å; R36-E191 VanDerWaalsContact NH2-CD 3.28Å; R36-E191 IonicContact NH2-OE1 3.16Å; R36-E191 PolarHBondContact NH2-OE1 3.39Å; R36-E191 IonicContact NH2-OE2 3.41Å; R36-E191 PolarHBondContact NH2-OE2 2.92Å; R36-L195 HydrophobicContact CG-CD1 4.32Å; R36-L195 HydrophobicContact CG-CD2 4.1Å; R36-E259 PolarHBondContact N-OE1 3.16Å
37	Y	90.3	Very high	84.4	Confident	42 Å²	42	51.5 Å²	51.5	17%	0.165	29%	0.288	C	S	.	.	H	α-helix	trans	-77.9	-34.5	174.4	-77.2	-86.3	0	0	0	112.3	A31 S34 S35 L39 A40 L41 R194 L195 I198	A31-Y37 HydrophobicContact CB-CE2 4Å; S34-Y37 PolarHBondContact O-N 3.33Å; S35-Y37 PolarHBondContact O-N 3.48Å; Y37-L39 VanDerWaalsContact C-N 3.3Å; Y37-L39 PolarHBondContact O-N 3.3Å; Y37-A40 WeakPolarHBondContact O-CB 3.18Å; Y37-A40 PolarHBondContact O-N 3.24Å; Y37-A40 VanDerWaalsContact O-N 3.16Å; Y37-L41 WeakPolarHBondContact O-CG 3.36Å; Y37-L41 PolarHBondContact O-N 3.43Å; Y37-R194 PolarHBondContact OH-NE 3.39Å; Y37-R194 VanDerWaalsContact OH-NE 3.08Å; Y37-R194 PolarHBondContact OH-NH1 3.48Å; Y37-R194 PolarHBondContact OH-NH2 3.04Å; Y37-L195 HydrophobicContact CD1-CD2 4.17Å; Y37-L195 HydrophobicContact CE1-CD2 4.36Å; Y37-L195 HydrophobicContact CG-CD2 4.41Å; Y37-I198 HydrophobicContact CD1-CD1 4.07Å; Y37-I198 HydrophobicContact CE1-CD1 3.97Å
38	G	91.6	Very high	86.2	Confident	32 Å²	32	45.5 Å²	45.5	33%	0.33	26%	0.259	S	S	.	.	H	α-helix	trans	-56.8	-45.6	168.9	0	0	0	0	0	111.6	S34 S35 A40 L41 L42	S34-G38 PolarHBondContact O-N 3.36Å; S34-G38 VanDerWaalsContact O-N 3.09Å; S35-G38 PolarHBondContact O-N 2.72Å; G38-A40 PolarHBondContact O-N 2.7Å; G38-L41 PolarHBondContact O-N 3.47Å; G38-L42 PolarHBondContact O-N 2.88Å
39	L	93.3	Very high	87.5	Confident	9 Å²	9	37.5 Å²	37.5	5%	0.047	23%	0.229	C	C	.	.	H	α-helix	trans	-59.7	-44.5	172.5	178.6	61.1	0	0	0	111.8	S35 Y37 L41 L42 S43 M179 M182 W183 W186 W241 V245	S35-L39 PolarHBondContact O-N 3.35Å; Y37-L39 VanDerWaalsContact C-N 3.3Å; Y37-L39 PolarHBondContact O-N 3.3Å; L39-L41 PolarHBondContact O-N 3.47Å; L39-L42 PolarHBondContact O-N 3.04Å; L39-S43 VanDerWaalsContact O-CB 3.24Å; L39-S43 WeakPolarHBondContact O-CB 3.49Å; L39-S43 PolarHBondContact O-N 2.76Å; L39-S43 PolarHBondContact O-OG 3.32Å; L39-M179 HydrophobicContact CD1-CE 4.45Å; L39-M179 HydrophobicContact CG-CE 4.35Å; L39-M182 HydrophobicContact CD2-CG 3.99Å; L39-W183 HydrophobicContact CB-CH2 4.35Å; L39-W183 HydrophobicContact CD2-CH2 4.12Å; L39-W183 HydrophobicContact CD2-CZ3 4.18Å; L39-W183 HydrophobicContact CG-CH2 4.05Å; L39-W183 HydrophobicContact CG-CZ2 4.36Å; L39-W186 HydrophobicContact CD2-CB 3.93Å; L39-W186 HydrophobicContact CD2-CD2 3.63Å; L39-W186 HydrophobicContact CD2-CE3 4.1Å; L39-W186 HydrophobicContact CD2-CG 3.55Å; L39-W241 HydrophobicContact CD1-CH2 4.2Å; L39-W241 HydrophobicContact CD1-CZ3 4.43Å; L39-V245 HydrophobicContact CD1-CB 4.45Å; L39-V245 HydrophobicContact CD1-CG1 3.63Å; L39-V245 HydrophobicContact CD1-CG2 4.01Å
40	A	93.1	Very high	88.6	Confident	0 Å²	0	37.2 Å²	37.2	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-60.2	-42.8	178.2	0	0	0	0	0	112.7	R36 Y37 G38 S43 S44 W183 L195 I198	R36-A40 PolarHBondContact O-N 3.1Å; Y37-A40 WeakPolarHBondContact O-CB 3.18Å; Y37-A40 PolarHBondContact O-N 3.24Å; Y37-A40 VanDerWaalsContact O-N 3.16Å; G38-A40 PolarHBondContact O-N 2.7Å; A40-S43 PolarHBondContact O-N 3.4Å; A40-S44 WeakPolarHBondContact O-CB 3.34Å; A40-S44 PolarHBondContact O-N 2.96Å; A40-W183 HydrophobicContact CB-CH2 3.76Å; A40-W183 HydrophobicContact CB-CZ2 3.89Å; A40-L195 HydrophobicContact CB-CD2 4.11Å; A40-I198 HydrophobicContact CB-CB 4.18Å; A40-I198 HydrophobicContact CB-CG2 3.74Å
41	L	93.3	Very high	89.5	Confident	114 Å²	114	34.2 Å²	34.2	60%	0.597	21%	0.205	S	C	*	.	H	α-helix	trans	-69.1	-43.2	178.1	-68.8	174.1	0	0	0	112.4	Y37 G38 L39 S43 S44 Y45 I198	Y37-L41 WeakPolarHBondContact O-CG 3.36Å; Y37-L41 PolarHBondContact O-N 3.43Å; G38-L41 PolarHBondContact O-N 3.47Å; L39-L41 PolarHBondContact O-N 3.47Å; L41-S43 VanDerWaalsContact C-N 3.31Å; L41-S43 PolarHBondContact O-N 3.44Å; L41-S44 VanDerWaalsContact O-CB 3.28Å; L41-S44 WeakPolarHBondContact O-CB 3.43Å; L41-S44 PolarHBondContact O-N 3.42Å; L41-Y45 PolarHBondContact O-N 3.49Å; L41-I198 HydrophobicContact CD2-CG2 4.14Å
42	L	93.9	Very high	90.8	Very high	37 Å²	37	31.5 Å²	31.5	19%	0.194	18%	0.183	C	C	.	.	H	α-helix	trans	-63.9	-38.6	175.2	-78.1	166.6	0	0	0	112	G38 L39 Y45 G46 W237 W241 L244 V245	G38-L42 PolarHBondContact O-N 2.88Å; L39-L42 PolarHBondContact O-N 3.04Å; L42-Y45 PolarHBondContact O-N 3.3Å; L42-G46 PolarHBondContact O-N 3.05Å; L42-W237 PolarHBondContact O-NE1 3.46Å; L42-W241 HydrophobicContact CB-CZ3 4.47Å; L42-L244 HydrophobicContact CD1-CB 3.7Å; L42-L244 HydrophobicContact CD1-CD1 4.19Å; L42-L244 HydrophobicContact CD2-CD1 4Å; L42-V245 HydrophobicContact CB-CG2 4.34Å; L42-V245 HydrophobicContact CD1-CG2 3.9Å
43	S	95.1	Very high	92.1	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-65.8	-40.4	174.1	-54.4	0	0	0	0	111	L39 A40 L41 Y45 G46 F47 M179	L39-S43 VanDerWaalsContact O-CB 3.24Å; L39-S43 WeakPolarHBondContact O-CB 3.49Å; L39-S43 PolarHBondContact O-N 2.76Å; L39-S43 PolarHBondContact O-OG 3.32Å; A40-S43 PolarHBondContact O-N 3.4Å; L41-S43 VanDerWaalsContact C-N 3.31Å; L41-S43 PolarHBondContact O-N 3.44Å; S43-Y45 PolarHBondContact O-N 3.34Å; S43-G46 CarbonylContact O-C 3.53Å; S43-G46 WeakPolarHBondContact O-CA 3.31Å; S43-G46 PolarHBondContact O-N 3Å; S43-G46 VanDerWaalsContact O-N 3.07Å; S43-F47 VanDerWaalsContact O-CD2 3.25Å; S43-F47 WeakPolarHBondContact O-CD2 3.27Å; S43-F47 PolarHBondContact O-N 3.48Å; S43-M179 WeakPolarHBondContact OG-CE 3.5Å; S43-M179 PolarHBondContact OG-SD 3.02Å; S43-M179 VanDerWaalsContact OG-SD 3.39Å
44	S	95.3	Very high	92.9	Very high	16 Å²	16	21.4 Å²	21.4	11%	0.112	11%	0.112	C	C	.	.	H	α-helix	trans	-57.4	-47.3	172.2	-155.5	0	0	0	0	111.9	A40 L41 G46 F47 F48 I198 S199 G202	A40-S44 WeakPolarHBondContact O-CB 3.34Å; A40-S44 PolarHBondContact O-N 2.96Å; L41-S44 VanDerWaalsContact O-CB 3.28Å; L41-S44 WeakPolarHBondContact O-CB 3.43Å; L41-S44 PolarHBondContact O-N 3.42Å; S44-G46 VanDerWaalsContact C-N 3.25Å; S44-G46 PolarHBondContact O-N 3.34Å; S44-F47 PolarHBondContact O-N 2.78Å; S44-F48 WeakPolarHBondContact O-CB 3.22Å; S44-F48 PolarHBondContact O-N 3.21Å; S44-I198 WeakPolarHBondContact CB-O 3.21Å; S44-I198 PolarHBondContact OG-O 2.86Å; S44-S199 VanDerWaalsContact CA-O 3.25Å; S44-S199 WeakPolarHBondContact CA-O 3.03Å; S44-G202 VanDerWaalsContact O-CA 3.28Å; S44-G202 WeakPolarHBondContact O-CA 3.28Å; S44-G202 WeakPolarHBondContact OG-CA 3.43Å; S44-G202 PolarHBondContact OG-N 2.93Å
45	Y	95.9	Very high	92.9	Very high	82 Å²	82	21.1 Å²	21.1	32%	0.322	11%	0.11	S	C	.	.	H	α-helix	trans	-63.7	-33.4	174.9	-175.4	-142.5	0	0	0	112.1	L41 L42 S43 F48 V49 W237 L240	L41-Y45 PolarHBondContact O-N 3.49Å; L42-Y45 PolarHBondContact O-N 3.3Å; S43-Y45 PolarHBondContact O-N 3.34Å; Y45-F48 HydrophobicContact CD2-CB 4.47Å; Y45-F48 HydrophobicContact CD2-CD1 4.2Å; Y45-F48 HydrophobicContact CE2-CD1 4.21Å; Y45-F48 WeakPolarHBondContact O-CB 3.26Å; Y45-F48 PolarHBondContact O-N 3.02Å; Y45-V49 HydrophobicContact CD2-CG2 4.3Å; Y45-V49 HydrophobicContact CE2-CG2 3.92Å; Y45-V49 WeakPolarHBondContact O-CG2 3.48Å; Y45-V49 PolarHBondContact O-N 2.92Å; Y45-W237 AromaticContact CD1-CD1 3.36Å; Y45-W237 HydrophobicContact CD1-CG 4.49Å; Y45-W237 HydrophobicContact CE1-CB 4.37Å; Y45-W237 AromaticContact CE1-CD1 3.61Å; Y45-W237 HydrophobicContact CE1-CG 4.41Å; Y45-W237 AromaticContact CG-CD1 3.85Å; Y45-L240 HydrophobicContact CE1-CD1 4.31Å
46	G	96.3	Very high	92.8	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-64	-48.8	172.9	0	0	0	0	0	113.2	L42 S43 S44 F48 V49 V50 W237	L42-G46 PolarHBondContact O-N 3.05Å; S43-G46 CarbonylContact O-C 3.53Å; S43-G46 WeakPolarHBondContact O-CA 3.31Å; S43-G46 PolarHBondContact O-N 3Å; S43-G46 VanDerWaalsContact O-N 3.07Å; S44-G46 VanDerWaalsContact C-N 3.25Å; S44-G46 PolarHBondContact O-N 3.34Å; G46-F48 VanDerWaalsContact C-N 3.27Å; G46-F48 PolarHBondContact O-N 3.39Å; G46-V49 PolarHBondContact O-N 3.31Å; G46-V50 WeakPolarHBondContact O-CB 3.38Å; G46-V50 VanDerWaalsContact O-CG2 3.23Å; G46-V50 WeakPolarHBondContact O-CG2 3.49Å; G46-V50 PolarHBondContact O-N 3.31Å; G46-W237 VanDerWaalsContact CA-CZ2 3.42Å
47	F	95.8	Very high	92.6	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-65.1	-32.2	176	-78.8	-69.4	0	0	0	112.7	S43 S44 Y51 M136 F176 M179 S199 Y200 A203	S43-F47 VanDerWaalsContact O-CD2 3.25Å; S43-F47 WeakPolarHBondContact O-CD2 3.27Å; S43-F47 PolarHBondContact O-N 3.48Å; S44-F47 PolarHBondContact O-N 2.78Å; F47-Y51 PolarHBondContact O-N 2.69Å; F47-M136 HydrophobicContact CE2-CE 4.32Å; F47-F176 HydrophobicContact CD1-CE1 4.34Å; F47-F176 HydrophobicContact CD1-CE2 4.33Å; F47-F176 HydrophobicContact CD1-CZ 4.08Å; F47-F176 AromaticContact CE1-CD1 3.93Å; F47-F176 HydrophobicContact CE1-CD1 3.93Å; F47-F176 AromaticContact CE1-CD2 4Å; F47-F176 HydrophobicContact CE1-CD2 4Å; F47-F176 AromaticContact CE1-CE1 3.84Å; F47-F176 HydrophobicContact CE1-CE1 3.84Å; F47-F176 AromaticContact CE1-CE2 3.92Å; F47-F176 HydrophobicContact CE1-CE2 3.92Å; F47-F176 HydrophobicContact CE1-CG 4.02Å; F47-F176 AromaticContact CE1-CZ 3.84Å; F47-F176 HydrophobicContact CE1-CZ 3.84Å; F47-F176 HydrophobicContact CZ-CD1 4.36Å; F47-M179 HydrophobicContact CE2-CB 3.99Å; F47-M179 HydrophobicContact CE2-CG 3.79Å; F47-M179 HydrophobicContact CE2-SD 4.49Å; F47-M179 HydrophobicContact CZ-CB 3.83Å; F47-M179 HydrophobicContact CZ-CG 4.16Å; F47-S199 WeakPolarHBondContact CD2-O 3.23Å; F47-Y200 HydrophobicContact CD1-CD1 4.3Å; F47-Y200 HydrophobicContact CD1-CE1 4.36Å; F47-Y200 HydrophobicContact CD2-CD1 4.11Å; F47-Y200 HydrophobicContact CD2-CE1 4.17Å; F47-Y200 HydrophobicContact CE1-CD1 4.14Å; F47-Y200 AromaticContact CE1-CE1 3.76Å; F47-Y200 HydrophobicContact CE1-CE1 3.76Å; F47-Y200 AromaticContact CE2-CD1 3.96Å; F47-Y200 HydrophobicContact CE2-CD1 3.96Å; F47-Y200 AromaticContact CE2-CE1 3.56Å; F47-Y200 HydrophobicContact CE2-CE1 3.56Å; F47-Y200 HydrophobicContact CG-CD1 4.31Å; F47-Y200 AromaticContact CZ-CD1 3.99Å; F47-Y200 HydrophobicContact CZ-CD1 3.99Å; F47-Y200 AromaticContact CZ-CE1 3.33Å; F47-Y200 HydrophobicContact CZ-CE1 3.33Å; F47-A203 HydrophobicContact CB-CB 4.16Å; F47-A203 WeakPolarHBondContact O-CA 3.5Å
48	F	96	Very high	92.1	Very high	47 Å²	47	19.3 Å²	19.3	21%	0.206	10%	0.103	C	C	.	.	H	α-helix	trans	-56.7	-54.5	169.7	175.5	-80.3	0	0	0	110.8	S44 Y45 G46 V50 Y51 S52 G202 L205 G206 V209	S44-F48 WeakPolarHBondContact O-CB 3.22Å; S44-F48 PolarHBondContact O-N 3.21Å; Y45-F48 HydrophobicContact CD2-CB 4.47Å; Y45-F48 HydrophobicContact CD2-CD1 4.2Å; Y45-F48 HydrophobicContact CE2-CD1 4.21Å; Y45-F48 WeakPolarHBondContact O-CB 3.26Å; Y45-F48 PolarHBondContact O-N 3.02Å; G46-F48 VanDerWaalsContact C-N 3.27Å; G46-F48 PolarHBondContact O-N 3.39Å; F48-V50 PolarHBondContact O-N 3.35Å; F48-Y51 PolarHBondContact O-N 3.14Å; F48-S52 WeakPolarHBondContact O-CB 3.11Å; F48-S52 PolarHBondContact O-N 3.06Å; F48-S52 PolarHBondContact O-OG 3.28Å; F48-G202 WeakPolarHBondContact CA-O 3.35Å; F48-G202 PolarHBondContact N-O 3.41Å; F48-L205 HydrophobicContact CD2-CB 3.99Å; F48-L205 HydrophobicContact CE2-CB 4.47Å; F48-G206 WeakPolarHBondContact O-CA 3.38Å; F48-V209 HydrophobicContact CE2-CB 3.86Å; F48-V209 HydrophobicContact CE2-CG1 4.39Å; F48-V209 HydrophobicContact CE2-CG2 3.88Å; F48-V209 HydrophobicContact CZ-CB 3.9Å; F48-V209 HydrophobicContact CZ-CG1 3.97Å; F48-V209 HydrophobicContact CZ-CG2 4.29Å
49	V	96.2	Very high	91.6	Very high	2 Å²	2	18.3 Å²	18.3	1%	0.012	9%	0.09	C	C	.	.	H	α-helix	trans	-59.2	-48.8	179.2	167.5	0	0	0	0	111.6	Y45 G46 Y51 S52 L53 V140 V233 W237	Y45-V49 HydrophobicContact CD2-CG2 4.3Å; Y45-V49 HydrophobicContact CE2-CG2 3.92Å; Y45-V49 WeakPolarHBondContact O-CG2 3.48Å; Y45-V49 PolarHBondContact O-N 2.92Å; G46-V49 PolarHBondContact O-N 3.31Å; V49-Y51 VanDerWaalsContact C-N 3.35Å; V49-Y51 PolarHBondContact O-N 3.03Å; V49-S52 PolarHBondContact O-N 3.21Å; V49-L53 HydrophobicContact CG1-CD1 3.86Å; V49-L53 HydrophobicContact CG1-CG 4.38Å; V49-L53 VanDerWaalsContact O-CG 3.32Å; V49-L53 WeakPolarHBondContact O-CG 3.4Å; V49-L53 PolarHBondContact O-N 3.21Å; V49-V140 HydrophobicContact CG1-CG1 4.13Å; V49-V233 HydrophobicContact CG2-CG1 3.96Å; V49-W237 HydrophobicContact CG2-CB 4.05Å; V49-W237 HydrophobicContact CG2-CG 4.15Å
50	V	95.2	Very high	91.3	Very high	2 Å²	2	17.9 Å²	17.9	1%	0.012	9%	0.088	C	C	.	.	H	α-helix	trans	-52.5	-51.3	178.8	162.9	0	0	0	0	111.2	G46 F48 L53 R54 V140 E172 T175	G46-V50 WeakPolarHBondContact O-CB 3.38Å; G46-V50 VanDerWaalsContact O-CG2 3.23Å; G46-V50 WeakPolarHBondContact O-CG2 3.49Å; G46-V50 PolarHBondContact O-N 3.31Å; F48-V50 PolarHBondContact O-N 3.35Å; V50-L53 PolarHBondContact O-N 3.45Å; V50-R54 PolarHBondContact O-N 3.3Å; V50-R54 VanDerWaalsContact O-N 3.11Å; V50-V140 HydrophobicContact CG2-CG1 4.46Å; V50-V140 HydrophobicContact CG2-CG2 3.62Å; V50-E172 HydrophobicContact CG1-CG 3.6Å; V50-E172 WeakPolarHBondContact CG1-OE1 3.33Å; V50-T175 HydrophobicContact CG2-CG2 4.13Å
51	Y	92.1	Very high	90.9	Very high	13 Å²	13	18.2 Å²	18.2	5%	0.051	9%	0.09	C	C	.	.	H	α-helix	trans	-73.2	-32.2	-179.8	-89.1	-106.5	0	0	0	113.1	F47 F48 V49 L53 R54 V55 F176 A203 T207 F303	F47-Y51 PolarHBondContact O-N 2.69Å; F48-Y51 PolarHBondContact O-N 3.14Å; V49-Y51 VanDerWaalsContact C-N 3.35Å; V49-Y51 PolarHBondContact O-N 3.03Å; Y51-L53 VanDerWaalsContact C-N 3.32Å; Y51-L53 PolarHBondContact O-N 3.26Å; Y51-R54 PolarHBondContact O-N 3.43Å; Y51-V55 WeakPolarHBondContact O-CG1 3.4Å; Y51-V55 WeakPolarHBondContact O-CG2 3.45Å; Y51-V55 PolarHBondContact O-N 2.84Å; Y51-F176 AromaticContact CE2-CE2 3.87Å; Y51-F176 HydrophobicContact CE2-CE2 3.87Å; Y51-F176 AromaticContact CE2-CZ 3.71Å; Y51-F176 HydrophobicContact CE2-CZ 3.71Å; Y51-A203 WeakPolarHBondContact CB-O 3.37Å; Y51-A203 HydrophobicContact CD1-CB 4.16Å; Y51-A203 HydrophobicContact CD2-CB 3.26Å; Y51-A203 HydrophobicContact CE1-CB 4.23Å; Y51-A203 HydrophobicContact CE2-CB 3.36Å; Y51-A203 HydrophobicContact CG-CB 3.68Å; Y51-T207 WeakPolarHBondContact CD1-OG1 3.33Å; Y51-F303 HydrophobicContact CE1-CE1 4.34Å; Y51-F303 HydrophobicContact CE1-CZ 4.27Å
52	S	93.1	Very high	90.2	Very high	2 Å²	2	14 Å²	14	1%	0.014	7%	0.069	C	C	.	.	H	α-helix	trans	-62.5	-39	172.6	-62.1	0	0	0	0	112.4	F48 V49 R54 N56 G206	F48-S52 WeakPolarHBondContact O-CB 3.11Å; F48-S52 PolarHBondContact O-N 3.06Å; F48-S52 PolarHBondContact O-OG 3.28Å; V49-S52 PolarHBondContact O-N 3.21Å; S52-R54 VanDerWaalsContact C-N 3.33Å; S52-N56 PolarHBondContact O-N 3.23Å; S52-G206 PolarHBondContact OG-O 2.91Å; S52-G206 VanDerWaalsContact OG-O 3.12Å
53	L	92.3	Very high	89.6	Confident	2 Å²	2	13.2 Å²	13.2	1%	0.01	7%	0.065	C	C	.	.	H	α-helix	trans	-67.2	-33.5	174.3	-68.7	169.4	0	0	0	112.3	V49 V50 Y51 N56 T143 A144 T147 F230	V49-L53 HydrophobicContact CG1-CD1 3.86Å; V49-L53 HydrophobicContact CG1-CG 4.38Å; V49-L53 VanDerWaalsContact O-CG 3.32Å; V49-L53 WeakPolarHBondContact O-CG 3.4Å; V49-L53 PolarHBondContact O-N 3.21Å; V50-L53 PolarHBondContact O-N 3.45Å; Y51-L53 VanDerWaalsContact C-N 3.32Å; Y51-L53 PolarHBondContact O-N 3.26Å; L53-N56 PolarHBondContact O-ND2 3.47Å; L53-N56 PolarHBondContact O-OD1 3.31Å; L53-T143 HydrophobicContact CB-CG2 4.36Å; L53-T143 HydrophobicContact CD1-CG2 4.12Å; L53-A144 HydrophobicContact CD1-CB 4.19Å; L53-T147 HydrophobicContact CD2-CG2 3.78Å; L53-F230 HydrophobicContact CD2-CB 3.93Å; L53-F230 WeakPolarHBondContact CD2-O 3.33Å
54	R	88.4	Confident	89.2	Confident	20 Å²	20	13.2 Å²	13.2	8%	0.075	7%	0.065	C	C	.	.	H	α-helix	trans	-73.3	-45.8	-179.7	-172.7	-175.1	-66.3	-164.1	-2.3	113.2	V50 Y51 S52 F112 Y116 E172	V50-R54 PolarHBondContact O-N 3.3Å; V50-R54 VanDerWaalsContact O-N 3.11Å; Y51-R54 PolarHBondContact O-N 3.43Å; S52-R54 VanDerWaalsContact C-N 3.33Å; R54-F112 HydrophobicContact CG-CE1 4.08Å; R54-F112 HydrophobicContact CG-CE2 4.49Å; R54-F112 HydrophobicContact CG-CZ 4.04Å; R54-Y116 VanDerWaalsContact NH2-CZ 3.32Å; R54-Y116 PolarHBondContact NH2-OH 3.06Å; R54-E172 IonicContact CZ-OE1 3.11Å; R54-E172 IonicContact NE-OE1 2.79Å; R54-E172 PolarHBondContact NE-OE1 2.73Å; R54-E172 IonicContact NH2-OE1 2.66Å; R54-E172 PolarHBondContact NH2-OE1 3.23Å
55	V	85.8	Confident	88.6	Confident	3 Å²	3	13.6 Å²	13.6	2%	0.018	7%	0.065	C	C	.	.	H	α-helix	trans	-85.9	-12.8	-169.6	-55.6	0	0	0	0	113.9	Y51 L57 S58 T207 A210 L211 L307	Y51-V55 WeakPolarHBondContact O-CG1 3.4Å; Y51-V55 WeakPolarHBondContact O-CG2 3.45Å; Y51-V55 PolarHBondContact O-N 2.84Å; V55-L57 VanDerWaalsContact C-N 3.25Å; V55-L57 PolarHBondContact O-N 3.37Å; V55-S58 PolarHBondContact O-N 2.99Å; V55-S58 PolarHBondContact O-OG 3.48Å; V55-T207 HydrophobicContact CG1-CG2 4.13Å; V55-A210 HydrophobicContact CG2-CB 3.58Å; V55-L211 HydrophobicContact CB-CD2 4.14Å; V55-L211 HydrophobicContact CG2-CD2 4.18Å; V55-L211 HydrophobicContact CG2-CG 4.33Å; V55-L307 HydrophobicContact CG1-CD1 3.96Å; V55-L307 HydrophobicContact CG1-CD2 4.46Å
56	N	85.9	Confident	87.5	Confident	0 Å²	0	12.4 Å²	12.4	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-56	-37.7	-176.8	56.8	20.4	0	0	0	113.7	S52 L53 A60 V226 F227 F230	S52-N56 PolarHBondContact O-N 3.23Å; L53-N56 PolarHBondContact O-ND2 3.47Å; L53-N56 PolarHBondContact O-OD1 3.31Å; N56-A60 WeakPolarHBondContact O-CB 3.01Å; N56-A60 PolarHBondContact O-N 2.86Å; N56-V226 HydrophobicContact CB-CG1 3.65Å; N56-F227 HydrophobicContact CB-CE1 4.31Å; N56-F227 WeakPolarHBondContact OD1-CE1 3.41Å; N56-F230 HydrophobicContact CB-CD2 4.15Å
57	L	86.1	Confident	85.8	Confident	4 Å²	4	15.9 Å²	15.9	2%	0.021	8%	0.083	C	C	.	.	H	α-helix	trans	-72.4	-32	-175.2	179.5	69.3	0	0	0	112.7	V55 V59 A60 M61 M64 I108 L109 R165 F227	V55-L57 VanDerWaalsContact C-N 3.25Å; V55-L57 PolarHBondContact O-N 3.37Å; L57-V59 PolarHBondContact O-N 3.35Å; L57-A60 PolarHBondContact O-N 3.5Å; L57-M61 HydrophobicContact CD1-CE 4.01Å; L57-M61 HydrophobicContact CD2-CE 4.27Å; L57-M61 HydrophobicContact CG-CE 4.15Å; L57-M61 WeakPolarHBondContact O-CB 3.21Å; L57-M61 PolarHBondContact O-N 3.15Å; L57-M64 HydrophobicContact CD1-SD 4.09Å; L57-I108 HydrophobicContact CD2-CG2 3.87Å; L57-L109 HydrophobicContact CD2-CD2 3.94Å; L57-L109 HydrophobicContact CG-CD2 4.06Å; L57-R165 HydrophobicContact CD2-CG 4.37Å; L57-R165 VanDerWaalsContact CD2-CZ 3.46Å; L57-F227 HydrophobicContact CB-CE1 4.24Å; L57-F227 HydrophobicContact CB-CZ 4.33Å; L57-F227 HydrophobicContact CD1-CE1 4.37Å; L57-F227 HydrophobicContact CD1-CZ 3.75Å
58	S	79.9	Confident	83.6	Confident	20 Å²	20	20.6 Å²	20.6	14%	0.14	11%	0.112	C	C	.	.	H	α-helix	trans	-64.5	-33.1	-179	61.7	0	0	0	0	111.9	V55	V55-S58 PolarHBondContact O-N 2.99Å; V55-S58 PolarHBondContact O-OG 3.48Å
59	V	81.4	Confident	80.9	Confident	11 Å²	11	25.3 Å²	25.3	7%	0.067	14%	0.135	C	C	.	.	H	α-helix	trans	-81.5	-46.5	173.6	-178.6	0	0	0	0	111.1	L57 M61 V62 L211	L57-V59 PolarHBondContact O-N 3.35Å; V59-M61 VanDerWaalsContact C-N 3.27Å; V59-M61 PolarHBondContact O-N 2.95Å; V59-V62 PolarHBondContact O-N 3.4Å; V59-L211 HydrophobicContact CG2-CD2 3.53Å
60	A	86.5	Confident	78.3	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-61.1	-34.5	-179.7	0	0	0	0	0	112.7	N56 L57 V62 D63 M64 W223 F227	N56-A60 WeakPolarHBondContact O-CB 3.01Å; N56-A60 PolarHBondContact O-N 2.86Å; L57-A60 PolarHBondContact O-N 3.5Å; A60-V62 PolarHBondContact O-N 3.48Å; A60-D63 PolarHBondContact O-N 3.03Å; A60-M64 HydrophobicContact CB-SD 4.44Å; A60-M64 VanDerWaalsContact O-CG 3.27Å; A60-M64 WeakPolarHBondContact O-CG 3.33Å; A60-M64 PolarHBondContact O-N 2.95Å; A60-W223 HydrophobicContact CB-CB 4.28Å; A60-F227 HydrophobicContact CB-CE2 4.01Å; A60-F227 HydrophobicContact CB-CZ 3.74Å
61	M	84.9	Confident	75.5	Confident	8 Å²	8	36.2 Å²	36.2	4%	0.039	20%	0.197	C	C	.	.	H	α-helix	trans	-55.6	-34.4	178	-173.2	69.2	70.3	0	0	112.3	L57 V59 D63 M64 L65 W100 Q105 I108 L109	L57-M61 HydrophobicContact CD1-CE 4.01Å; L57-M61 HydrophobicContact CD2-CE 4.27Å; L57-M61 HydrophobicContact CG-CE 4.15Å; L57-M61 WeakPolarHBondContact O-CB 3.21Å; L57-M61 PolarHBondContact O-N 3.15Å; V59-M61 VanDerWaalsContact C-N 3.27Å; V59-M61 PolarHBondContact O-N 2.95Å; M61-D63 VanDerWaalsContact C-N 3.26Å; M61-D63 PolarHBondContact O-N 3.24Å; M61-M64 PolarHBondContact O-N 3.14Å; M61-L65 HydrophobicContact CG-CD1 4.01Å; M61-L65 WeakPolarHBondContact O-CD1 3.46Å; M61-L65 VanDerWaalsContact O-CG 3.22Å; M61-L65 WeakPolarHBondContact O-CG 3.17Å; M61-L65 PolarHBondContact O-N 3.31Å; M61-L65 HydrophobicContact SD-CD1 4.41Å; M61-L65 HydrophobicContact SD-CG 4.47Å; M61-W100 HydrophobicContact CE-CZ3 4.45Å; M61-W100 HydrophobicContact SD-CE3 3.8Å; M61-W100 HydrophobicContact SD-CZ3 3.87Å; M61-Q105 HydrophobicContact SD-CG 4.31Å; M61-I108 HydrophobicContact CE-CB 4.07Å; M61-I108 HydrophobicContact CE-CD1 4.37Å; M61-I108 HydrophobicContact CE-CG2 3.69Å; M61-L109 HydrophobicContact CE-CD2 4.4Å; M61-L109 HydrophobicContact CE-CG 4.26Å
62	V	78.9	Confident	72.7	Confident	25 Å²	25	46.1 Å²	46.1	15%	0.152	24%	0.235	C	C	.	.	H	α-helix	trans	-64.6	-33.4	178.8	-178	0	0	0	0	111.6	V59 A60 I322	V59-V62 PolarHBondContact O-N 3.4Å; A60-V62 PolarHBondContact O-N 3.48Å; V62-I322 HydrophobicContact CG1-CD1 3.98Å; V62-I322 HydrophobicContact CG1-CG1 3.98Å
63	D	81.5	Confident	69.8	Low	21 Å²	21	48.8 Å²	48.8	11%	0.112	25%	0.253	C	S	.	.	H	α-helix	trans	-87.3	-25.4	178.5	-168.3	46.5	0	0	0	112.7	A60 M61 L65 H91 C218 W223	A60-D63 PolarHBondContact O-N 3.03Å; M61-D63 VanDerWaalsContact C-N 3.26Å; M61-D63 PolarHBondContact O-N 3.24Å; D63-L65 PolarHBondContact O-N 2.86Å; D63-H91 IonicContact OD1-CD2 3.73Å; D63-H91 IonicContact OD1-NE2 3.05Å; D63-H91 PolarHBondContact OD1-NE2 3.19Å; D63-C218 HydrophobicContact CB-CB 4.37Å; D63-W223 HydrophobicContact CB-CB 4.27Å; D63-W223 PolarHBondContact OD2-N 3.14Å
64	M	85.6	Confident	67.2	Low	0 Å²	0	56.2 Å²	56.2	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-71.1	-13.6	176.1	-69.1	173	82.2	0	0	113.3	L57 A60 M61 Y98 W100 A154 L161 W223 F227	L57-M64 HydrophobicContact CD1-SD 4.09Å; A60-M64 HydrophobicContact CB-SD 4.44Å; A60-M64 VanDerWaalsContact O-CG 3.27Å; A60-M64 WeakPolarHBondContact O-CG 3.33Å; A60-M64 PolarHBondContact O-N 2.95Å; M61-M64 PolarHBondContact O-N 3.14Å; M64-Y98 HydrophobicContact CB-CD2 4.18Å; M64-Y98 HydrophobicContact CE-CD2 4.27Å; M64-Y98 HydrophobicContact CE-CE2 4.01Å; M64-Y98 WeakPolarHBondContact O-CD2 3.49Å; M64-Y98 PolarHBondContact O-N 3.4Å; M64-W100 HydrophobicContact CB-CZ3 4.3Å; M64-W100 HydrophobicContact CE-CH2 3.45Å; M64-W100 VanDerWaalsContact CE-CH2 3.45Å; M64-W100 HydrophobicContact CE-CZ3 3.6Å; M64-W100 HydrophobicContact SD-CZ3 4.38Å; M64-A154 HydrophobicContact CE-CB 3.72Å; M64-L161 HydrophobicContact CE-CD2 4.24Å; M64-W223 HydrophobicContact CE-CD2 4.48Å; M64-W223 HydrophobicContact CE-CE3 4.17Å; M64-W223 HydrophobicContact CE-CH2 4.07Å; M64-W223 HydrophobicContact CE-CZ2 4.38Å; M64-W223 HydrophobicContact CE-CZ3 3.94Å; M64-W223 HydrophobicContact CG-CB 4.26Å; M64-W223 HydrophobicContact CG-CD2 3.58Å; M64-W223 HydrophobicContact CG-CE3 4.01Å; M64-W223 HydrophobicContact CG-CG 3.69Å; M64-W223 HydrophobicContact SD-CD2 4.3Å; M64-W223 HydrophobicContact SD-CE3 4.11Å; M64-W223 HydrophobicContact SD-CZ3 4.44Å; M64-F227 HydrophobicContact SD-CE2 4.49Å
65	L	82.4	Confident	64.9	Low	23 Å²	23	62.4 Å²	62.4	12%	0.12	32%	0.322	C	S	.	.	B	Isolated β-bridge	trans	-104.7	144.3	-171.3	-68.1	168.3	0	0	0	113.4	M61 D63 N67 V97 W100 Q105	M61-L65 HydrophobicContact CG-CD1 4.01Å; M61-L65 WeakPolarHBondContact O-CD1 3.46Å; M61-L65 VanDerWaalsContact O-CG 3.22Å; M61-L65 WeakPolarHBondContact O-CG 3.17Å; M61-L65 PolarHBondContact O-N 3.31Å; M61-L65 HydrophobicContact SD-CD1 4.41Å; M61-L65 HydrophobicContact SD-CG 4.47Å; D63-L65 PolarHBondContact O-N 2.86Å; L65-N67 PolarHBondContact O-N 2.94Å; L65-N67 VanDerWaalsContact O-N 3.11Å; L65-V97 WeakPolarHBondContact O-CG1 3.35Å; L65-W100 HydrophobicContact CD2-CB 3.83Å; L65-W100 HydrophobicContact CD2-CE3 4.1Å; L65-W100 HydrophobicContact CD2-CG 4.48Å; L65-Q105 VanDerWaalsContact CD1-CD 3.41Å; L65-Q105 HydrophobicContact CD1-CG 4.05Å; L65-Q105 VanDerWaalsContact CD1-NE2 3.29Å; L65-Q105 HydrophobicContact CD2-CG 4.15Å
66	N	72.8	Confident	62.5	Low	57 Å²	57	68.5 Å²	68.5	31%	0.305	37%	0.365	S	S	.	.			trans	-79.8	94.1	178	-165.2	-2.2	0	0	0	111.9	T68 V97 Y98 N99	N66-T68 PolarHBondContact O-N 2.95Å; N66-T68 VanDerWaalsContact OD1-CB 3.3Å; N66-T68 WeakPolarHBondContact OD1-CB 3.18Å; N66-T68 PolarHBondContact OD1-N 3.44Å; N66-T68 PolarHBondContact OD1-OG1 3.2Å; N66-V97 HydrophobicContact CB-CG1 3.6Å; N66-Y98 PolarHBondContact N-O 3.47Å; N66-N99 WeakPolarHBondContact CB-OD1 3.45Å; N66-N99 PolarHBondContact ND2-OD1 3.37Å
67	N	61.5	Low	60.4	Low	74 Å²	74	71.1 Å²	71.1	40%	0.396	39%	0.392	S	S	.	.	G	3₁₀ helix	trans	-73.8	-3.6	179.6	-67	-25.9	0	0	0	114.1	L65 H69 Q70	L65-N67 PolarHBondContact O-N 2.94Å; L65-N67 VanDerWaalsContact O-N 3.11Å; N67-H69 PolarHBondContact O-N 3Å; N67-H69 VanDerWaalsContact O-N 3.14Å; N67-Q70 PolarHBondContact O-N 2.87Å
68	T	49.2	Very low	58.6	Low	99 Å²	99	74.9 Å²	74.9	61%	0.607	42%	0.419	S	S	*	.	G	3₁₀ helix	trans	-65.4	-19.7	-175.1	-35.6	0	0	0	0	113.6	N66	N66-T68 PolarHBondContact O-N 2.95Å; N66-T68 VanDerWaalsContact OD1-CB 3.3Å; N66-T68 WeakPolarHBondContact OD1-CB 3.18Å; N66-T68 PolarHBondContact OD1-N 3.44Å; N66-T68 PolarHBondContact OD1-OG1 3.2Å
69	H	39.6	Very low	57.3	Low	146 Å²	146	80 Å²	80	68%	0.676	45%	0.449	S	S	*	.	G	3₁₀ helix	trans	-89.1	-20.7	178.2	-81.7	-82.9	0	0	0	114.7	N67	N67-H69 PolarHBondContact O-N 3Å; N67-H69 VanDerWaalsContact O-N 3.14Å
70	Q	41.8	Very low	56.2	Low	123 Å²	123	80.3 Å²	80.3	58%	0.575	45%	0.451	S	S	*	.	G	3₁₀ helix	trans	-80	-22.2	178.1	-92	176.9	-19.7	0	0	113.1	N67 R72 S73	N67-Q70 PolarHBondContact O-N 2.87Å; Q70-R72 PolarHBondContact O-N 3.32Å; Q70-S73 PolarHBondContact O-OG 3.07Å
71	S	35.8	Very low	54.6	Low	109 Å²	109	85.9 Å²	85.9	76%	0.762	49%	0.486	S	S	*	.	G	3₁₀ helix	trans	-75.9	-2.9	175.8	-45.1	0	0	0	0	114.2
72	R	34	Very low	53.2	Low	222 Å²	222	89.7 Å²	89.7	84%	0.838	51%	0.511	S	S	*	.	G	3₁₀ helix	trans	-110.2	-1.4	-176.9	-102.9	-176.9	179.9	172.9	1.1	115.1	Q70	Q70-R72 PolarHBondContact O-N 3.32Å
73	S	32.5	Very low	51.8	Low	57 Å²	57	92.5 Å²	92.5	40%	0.399	53%	0.525	S	S	.	.	S	Bend	trans	-90.5	107.2	164.6	46.6	0	0	0	0	108.6	Q70 H75	Q70-S73 PolarHBondContact O-OG 3.07Å; S73-H75 VanDerWaalsContact C-N 3.25Å; S73-H75 PolarHBondContact O-N 2.97Å
74	D	36.2	Very low	50	Low	159 Å²	159	99.5 Å²	99.5	85%	0.85	56%	0.563	S	S	*	*			trans	-51.9	88.3	165.3	-76.9	-39.6	0	0	0	109.8	S76	D74-S76 VanDerWaalsContact C-N 3.34Å; D74-S76 PolarHBondContact O-N 3.33Å; D74-S76 VanDerWaalsContact O-N 3.12Å
75	H	39.9	Very low	48.1	Very low	149 Å²	149	102.9 Å²	102.9	69%	0.69	58%	0.583	S	S	*	*			trans	-82.2	86.3	169.8	-82	-57.8	0	0	0	108.8	S73 G77	S73-H75 VanDerWaalsContact C-N 3.25Å; S73-H75 PolarHBondContact O-N 2.97Å; H75-G77 PolarHBondContact O-N 3.31Å
76	S	36.6	Very low	46.2	Very low	132 Å²	132	107.4 Å²	107.4	92%	0.923	61%	0.614	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.8	31.5	162.8	-54.5	0	0	0	0	113.2	D74	D74-S76 VanDerWaalsContact C-N 3.34Å; D74-S76 PolarHBondContact O-N 3.33Å; D74-S76 VanDerWaalsContact O-N 3.12Å
77	G	41.5	Very low	44.8	Very low	55 Å²	55	111.3 Å²	111.3	57%	0.567	64%	0.639	S	S	*	*	T	Hydrogen-bonded Turn	trans	-144	12.3	-167.8	0	0	0	0	0	115.7	H75 V79	H75-G77 PolarHBondContact O-N 3.31Å; G77-V79 PolarHBondContact O-N 3.07Å
78	S	48	Very low	44.2	Very low	83 Å²	83	116.1 Å²	116.1	58%	0.58	66%	0.66	S	S	*	*			trans	-73.3	100.3	170.1	63.1	0	0	0	0	109.4	C80	S78-C80 PolarHBondContact O-N 3.09Å; S78-C80 VanDerWaalsContact O-N 3.13Å
79	V	53.9	Low	44.2	Very low	128 Å²	128	115.1 Å²	115.1	78%	0.776	66%	0.655	S	S	*	*	S	Bend	trans	-59	-21.8	178.2	177.8	0	0	0	0	112.2	G77	G77-V79 PolarHBondContact O-N 3.07Å
80	C	56.5	Low	44.5	Very low	16 Å²	16	118.1 Å²	118.1	11%	0.108	67%	0.666	C	S	.	*	S	Bend	trans	-121.6	137	177.7	-57.6	0	0	0	0	110.5	S78 C385 Y387	S78-C80 PolarHBondContact O-N 3.09Å; S78-C80 VanDerWaalsContact O-N 3.13Å; C80-C385 VanDerWaalsContact CA-SG 3.53Å; C80-C385 HydrophobicContact CB-CB 3.65Å; C80-C385 WeakPolarHBondContact CB-SG 3.45Å; C80-C385 WeakPolarHBondContact SG-CA 3.13Å; C80-C385 WeakPolarHBondContact SG-CB 3.47Å; C80-C385 CovalentContact SG-SG 2.03Å; C80-C385 PolarHBondContact SG-SG 3.39Å; C80-Y387 HydrophobicContact CB-CE1 4.31Å; C80-Y387 WeakPolarHBondContact CB-OH 3.38Å
81	T	54	Low	45.2	Very low	118 Å²	118	114.8 Å²	114.8	72%	0.724	65%	0.65	S	S	*	*	P	Polyproline II helix	trans	-62.7	133.5	173.1	41.3	0	0	0	0	109.9	N83 Y387	T81-N83 PolarHBondContact O-N 3.06Å; T81-Y387 PolarHBondContact O-OH 3.39Å; T81-Y387 VanDerWaalsContact O-OH 3.05Å
82	P	55.5	Low	46	Very low	88 Å²	88	115.3 Å²	115.3	57%	0.571	64%	0.644	S	S	*	*	P	Polyproline II helix	trans	-54.9	138.9	169.9	-19.8	30.7	0	0	0	108.9	N84	P82-N84 PolarHBondContact O-N 3.36Å
83	N	49.5	Very low	47.1	Very low	84 Å²	84	111.7 Å²	111.7	45%	0.449	64%	0.637	S	S	.	*	P	Polyproline II helix	trans	-57.8	118.5	175	-135	4	0	0	0	107.4	T81 T85	T81-N83 PolarHBondContact O-N 3.06Å; N83-T85 PolarHBondContact O-N 3Å; N83-T85 PolarHBondContact O-OG1 3.17Å
84	N	43.5	Very low	48.2	Very low	168 Å²	168	113.7 Å²	113.7	90%	0.898	65%	0.651	S	S	*	*			trans	-60.8	86.6	177	-83	-13.6	0	0	0	108.8	P82	P82-N84 PolarHBondContact O-N 3.36Å
85	T	45.3	Very low	49.7	Very low	70 Å²	70	107.3 Å²	107.3	43%	0.429	62%	0.621	S	S	.	*			trans	-107.3	147.5	173.4	44.7	0	0	0	0	108.9	N83	N83-T85 PolarHBondContact O-N 3Å; N83-T85 PolarHBondContact O-OG1 3.17Å
86	P	42.9	Very low	51.3	Low	119 Å²	119	102.1 Å²	102.1	77%	0.773	61%	0.607	S	S	*	*			trans	-62.5	151.8	-173	-12.3	27.7	0	0	0	110.1	Q88	P86-Q88 PolarHBondContact O-N 2.66Å
87	V	43.7	Very low	53.5	Low	138 Å²	138	98.6 Å²	98.6	84%	0.836	58%	0.58	S	S	*	*			trans	-18.9	118.3	167.6	179.4	0	0	0	0	112.3	P89	V87-P89 VanDerWaalsContact O-N 3.14Å
88	Q	47.9	Very low	55.6	Low	175 Å²	175	97.6 Å²	97.6	82%	0.818	56%	0.559	S	S	*	*			trans	-46.8	121.3	173	-81.2	-173	-17.7	0	0	109.2	P86 K90	P86-Q88 PolarHBondContact O-N 2.66Å; Q88-K90 PolarHBondContact O-N 3.08Å
89	P	49.5	Very low	57.4	Low	79 Å²	79	99.8 Å²	99.8	51%	0.513	57%	0.565	S	S	.	*			trans	-59.5	132.5	175.7	21.3	-29	0	0	0	108.6	V87 H91 F219	V87-P89 VanDerWaalsContact O-N 3.14Å; P89-H91 PolarHBondContact O-N 2.93Å; P89-F219 HydrophobicContact CB-CE2 4.42Å; P89-F219 HydrophobicContact CB-CZ 4.1Å; P89-F219 HydrophobicContact CG-CE2 3.86Å; P89-F219 HydrophobicContact CG-CZ 3.88Å
90	K	45.5	Very low	58.9	Low	208 Å²	208	95.2 Å²	95.2	90%	0.904	53%	0.533	S	S	*	.			trans	-53.7	112	177.1	-82.5	-176.8	175.9	-179.4	0	108.7	Q88	Q88-K90 PolarHBondContact O-N 3.08Å
91	H	56	Low	60.1	Low	54 Å²	54	98.6 Å²	98.6	25%	0.25	55%	0.55	C	S	.	*			trans	-70.5	135.4	179.5	-157.5	62.8	0	0	0	109.2	D63 P89 Q93 F219	D63-H91 IonicContact OD1-CD2 3.73Å; D63-H91 IonicContact OD1-NE2 3.05Å; D63-H91 PolarHBondContact OD1-NE2 3.19Å; P89-H91 PolarHBondContact O-N 2.93Å; H91-Q93 HydrophobicContact CB-CG 4.4Å; H91-Q93 PolarHBondContact O-N 2.9Å; H91-F219 AromaticContact CE1-CD2 3.91Å; H91-F219 AromaticContact ND1-CD2 3.55Å; H91-F219 AromaticContact ND1-CE2 3.92Å
92	N	53.9	Low	61.1	Low	119 Å²	119	96 Å²	96	64%	0.636	54%	0.537	S	S	*	.			trans	-73.5	80.2	167.9	-81.1	-16.2	0	0	0	107.7	S94	N92-S94 PolarHBondContact O-N 3.04Å; N92-S94 PolarHBondContact O-OG 3.48Å
93	Q	55.6	Low	62.2	Low	147 Å²	147	94.3 Å²	94.3	69%	0.687	53%	0.531	S	S	*	.			trans	-70.2	80.3	173.8	-81.3	178.8	-23.2	0	0	109.6	H91	H91-Q93 HydrophobicContact CB-CG 4.4Å; H91-Q93 PolarHBondContact O-N 2.9Å
94	S	57.2	Low	63.9	Low	99 Å²	99	92 Å²	92	69%	0.692	52%	0.52	S	S	*	.			trans	-96.5	-12	172.2	34.8	0	0	0	0	113.1	N92	N92-S94 PolarHBondContact O-N 3.04Å; N92-S94 PolarHBondContact O-OG 3.48Å
95	A	67.7	Low	65.8	Low	25 Å²	25	85.4 Å²	85.4	21%	0.207	48%	0.483	C	S	.	.	S	Bend	trans	-103.5	152.1	-177.3	0	0	0	0	0	112.6	W223 P224	A95-W223 HydrophobicContact CB-CG 4.4Å; A95-P224 HydrophobicContact CB-CG 4.03Å
96	G	72.3	Confident	67.3	Low	39 Å²	39	83.1 Å²	83.1	40%	0.402	47%	0.474	S	S	.	.			trans	-63.3	142.4	-179	0	0	0	0	0	112.7	W223	G96-W223 PolarHBondContact O-NE1 3.47Å
97	V	82.9	Confident	69.3	Low	59 Å²	59	84.6 Å²	84.6	36%	0.358	46%	0.464	S	S	.	.			trans	-116.1	136.3	-179.8	-174.1	0	0	0	0	109.2	L65 N66	L65-V97 WeakPolarHBondContact O-CG1 3.35Å; N66-V97 HydrophobicContact CB-CG1 3.6Å
98	Y	86.9	Confident	71.4	Confident	34 Å²	34	78 Å²	78	13%	0.133	42%	0.424	C	S	.	.	B	Isolated β-bridge	trans	-113.2	146.6	-173.7	-54.3	-81	0	0	0	112.4	M64 N66 W100 A154 D155 W223	M64-Y98 HydrophobicContact CB-CD2 4.18Å; M64-Y98 HydrophobicContact CE-CD2 4.27Å; M64-Y98 HydrophobicContact CE-CE2 4.01Å; M64-Y98 WeakPolarHBondContact O-CD2 3.49Å; M64-Y98 PolarHBondContact O-N 3.4Å; N66-Y98 PolarHBondContact N-O 3.47Å; Y98-W100 AromaticContact CD1-CZ2 3.83Å; Y98-W100 HydrophobicContact CD1-CZ2 3.83Å; Y98-W100 AromaticContact CD2-CH2 3.66Å; Y98-W100 HydrophobicContact CD2-CH2 3.66Å; Y98-W100 AromaticContact CD2-CZ2 3.8Å; Y98-W100 HydrophobicContact CD2-CZ2 3.8Å; Y98-W100 HydrophobicContact CD2-CZ3 4.15Å; Y98-W100 HydrophobicContact CE1-CZ2 4.35Å; Y98-W100 HydrophobicContact CE2-CH2 4.12Å; Y98-W100 HydrophobicContact CE2-CZ2 4.34Å; Y98-W100 HydrophobicContact CG-CD2 4.42Å; Y98-W100 AromaticContact CG-CE2 3.8Å; Y98-W100 AromaticContact CG-CH2 3.88Å; Y98-W100 HydrophobicContact CG-CH2 3.88Å; Y98-W100 AromaticContact CG-CZ2 3.52Å; Y98-W100 HydrophobicContact CG-CZ2 3.52Å; Y98-W100 HydrophobicContact CG-CZ3 4.45Å; Y98-W100 PolarHBondContact O-N 3.45Å; Y98-A154 VanDerWaalsContact CE1-O 3.28Å; Y98-A154 WeakPolarHBondContact CE1-O 3.3Å; Y98-A154 HydrophobicContact CE2-CB 4.04Å; Y98-A154 VanDerWaalsContact OH-C 3.22Å; Y98-A154 WeakPolarHBondContact OH-CB 3.1Å; Y98-D155 WeakPolarHBondContact OH-CA 3.29Å; Y98-D155 PolarHBondContact OH-N 3.31Å; Y98-D155 VanDerWaalsContact OH-N 3.17Å; Y98-D155 PolarHBondContact OH-OD1 2.96Å; Y98-W223 HydrophobicContact CE2-CH2 4.2Å; Y98-W223 AromaticContact CE2-CZ2 3.62Å; Y98-W223 HydrophobicContact CE2-CZ2 3.62Å
99	N	85.9	Confident	73.1	Confident	129 Å²	129	72 Å²	72	69%	0.69	40%	0.398	S	S	*	.			trans	-97.8	72	174.5	-65	-30.2	0	0	0	109.7	N66	N66-N99 WeakPolarHBondContact CB-OD1 3.45Å; N66-N99 PolarHBondContact ND2-OD1 3.37Å
100	W	85.3	Confident	74.6	Confident	31 Å²	31	68.6 Å²	68.6	12%	0.117	38%	0.377	C	S	.	.			trans	-97.8	128.3	174.5	-58.7	-33	0	0	0	110.8	M61 M64 L65 Y98 T104 Q105 I108 A154 L161	M61-W100 HydrophobicContact CE-CZ3 4.45Å; M61-W100 HydrophobicContact SD-CE3 3.8Å; M61-W100 HydrophobicContact SD-CZ3 3.87Å; M64-W100 HydrophobicContact CB-CZ3 4.3Å; M64-W100 HydrophobicContact CE-CH2 3.45Å; M64-W100 VanDerWaalsContact CE-CH2 3.45Å; M64-W100 HydrophobicContact CE-CZ3 3.6Å; M64-W100 HydrophobicContact SD-CZ3 4.38Å; L65-W100 HydrophobicContact CD2-CB 3.83Å; L65-W100 HydrophobicContact CD2-CE3 4.1Å; L65-W100 HydrophobicContact CD2-CG 4.48Å; Y98-W100 AromaticContact CD1-CZ2 3.83Å; Y98-W100 HydrophobicContact CD1-CZ2 3.83Å; Y98-W100 AromaticContact CD2-CH2 3.66Å; Y98-W100 HydrophobicContact CD2-CH2 3.66Å; Y98-W100 AromaticContact CD2-CZ2 3.8Å; Y98-W100 HydrophobicContact CD2-CZ2 3.8Å; Y98-W100 HydrophobicContact CD2-CZ3 4.15Å; Y98-W100 HydrophobicContact CE1-CZ2 4.35Å; Y98-W100 HydrophobicContact CE2-CH2 4.12Å; Y98-W100 HydrophobicContact CE2-CZ2 4.34Å; Y98-W100 HydrophobicContact CG-CD2 4.42Å; Y98-W100 AromaticContact CG-CE2 3.8Å; Y98-W100 AromaticContact CG-CH2 3.88Å; Y98-W100 HydrophobicContact CG-CH2 3.88Å; Y98-W100 AromaticContact CG-CZ2 3.52Å; Y98-W100 HydrophobicContact CG-CZ2 3.52Å; Y98-W100 HydrophobicContact CG-CZ3 4.45Å; Y98-W100 PolarHBondContact O-N 3.45Å; W100-T104 HydrophobicContact CB-CG2 4.11Å; W100-T104 HydrophobicContact CG-CG2 4.14Å; W100-Q105 HydrophobicContact CB-CG 4.25Å; W100-Q105 PolarHBondContact O-NE2 2.91Å; W100-I108 HydrophobicContact CD2-CD1 3.94Å; W100-I108 HydrophobicContact CE3-CD1 3.75Å; W100-I108 HydrophobicContact CH2-CD1 4.4Å; W100-I108 HydrophobicContact CZ3-CD1 3.99Å; W100-A154 HydrophobicContact CH2-CB 4.25Å; W100-L161 HydrophobicContact CH2-CD2 3.55Å; W100-L161 HydrophobicContact CZ2-CD2 4.31Å; W100-L161 HydrophobicContact CZ3-CD2 4.01Å
101	D	81.6	Confident	76.7	Confident	87 Å²	87	59 Å²	59	47%	0.465	34%	0.336	S	S	.	.			trans	-72.1	166.1	175.6	74.5	-57	0	0	0	111.7	A103 T104 Q105	D101-A103 PolarHBondContact O-N 3.2Å; D101-A103 VanDerWaalsContact O-N 3.16Å; D101-A103 VanDerWaalsContact OD2-CB 3.28Å; D101-A103 WeakPolarHBondContact OD2-CB 3.47Å; D101-A103 PolarHBondContact OD2-N 3.24Å; D101-A103 VanDerWaalsContact OD2-N 3.14Å; D101-T104 PolarHBondContact O-N 3.09Å; D101-T104 VanDerWaalsContact O-N 3.14Å; D101-T104 WeakPolarHBondContact OD1-CB 3.38Å; D101-T104 PolarHBondContact OD1-N 3.04Å; D101-T104 PolarHBondContact OD1-OG1 3.49Å; D101-Q105 WeakPolarHBondContact O-CG 3.32Å; D101-Q105 PolarHBondContact O-N 3.33Å
102	S	74.3	Confident	78.4	Confident	63 Å²	63	56.8 Å²	56.8	44%	0.441	33%	0.326	S	S	.	.	H	α-helix	trans	-48.7	-40	178.3	-71.1	0	0	0	0	114.3	G106 R443	S102-G106 PolarHBondContact O-N 2.98Å; S102-R443 VanDerWaalsContact CB-NE 3.32Å; S102-R443 PolarHBondContact OG-NH2 3.42Å
103	A	79.6	Confident	80	Confident	54 Å²	54	51.6 Å²	51.6	45%	0.446	30%	0.297	S	S	.	.	H	α-helix	trans	-72.9	-44.4	-178.4	0	0	0	0	0	110.9	D101 Q105 G106 W107	D101-A103 PolarHBondContact O-N 3.2Å; D101-A103 VanDerWaalsContact O-N 3.16Å; D101-A103 VanDerWaalsContact OD2-CB 3.28Å; D101-A103 WeakPolarHBondContact OD2-CB 3.47Å; D101-A103 PolarHBondContact OD2-N 3.24Å; D101-A103 VanDerWaalsContact OD2-N 3.14Å; A103-Q105 VanDerWaalsContact C-N 3.34Å; A103-Q105 PolarHBondContact O-N 3.34Å; A103-G106 PolarHBondContact O-N 3.35Å; A103-G106 VanDerWaalsContact O-N 3.15Å; A103-W107 PolarHBondContact O-N 3.28Å
104	T	85.1	Confident	81.6	Confident	36 Å²	36	49.2 Å²	49.2	22%	0.221	28%	0.283	C	S	.	.	H	α-helix	trans	-60.9	-42	177.4	-61.5	0	0	0	0	112	W100 D101 G106 W107 I108 A158	W100-T104 HydrophobicContact CB-CG2 4.11Å; W100-T104 HydrophobicContact CG-CG2 4.14Å; D101-T104 PolarHBondContact O-N 3.09Å; D101-T104 VanDerWaalsContact O-N 3.14Å; D101-T104 WeakPolarHBondContact OD1-CB 3.38Å; D101-T104 PolarHBondContact OD1-N 3.04Å; D101-T104 PolarHBondContact OD1-OG1 3.49Å; T104-G106 VanDerWaalsContact C-N 3.31Å; T104-G106 PolarHBondContact O-N 3.46Å; T104-W107 PolarHBondContact O-N 3.47Å; T104-I108 HydrophobicContact CG2-CD1 3.85Å; T104-I108 HydrophobicContact CG2-CG1 4.36Å; T104-I108 VanDerWaalsContact O-CG1 3.32Å; T104-I108 WeakPolarHBondContact O-CG1 3.2Å; T104-I108 PolarHBondContact O-N 3.46Å; T104-A158 HydrophobicContact CG2-CB 3.67Å
105	Q	82.3	Confident	83.3	Confident	28 Å²	28	44.7 Å²	44.7	13%	0.131	25%	0.252	C	S	.	.	H	α-helix	trans	-57.6	-44.6	174.2	-65.9	168.1	27.1	0	0	111.6	M61 L65 W100 D101 A103 I108 L109	M61-Q105 HydrophobicContact SD-CG 4.31Å; L65-Q105 VanDerWaalsContact CD1-CD 3.41Å; L65-Q105 HydrophobicContact CD1-CG 4.05Å; L65-Q105 VanDerWaalsContact CD1-NE2 3.29Å; L65-Q105 HydrophobicContact CD2-CG 4.15Å; W100-Q105 HydrophobicContact CB-CG 4.25Å; W100-Q105 PolarHBondContact O-NE2 2.91Å; D101-Q105 WeakPolarHBondContact O-CG 3.32Å; D101-Q105 PolarHBondContact O-N 3.33Å; A103-Q105 VanDerWaalsContact C-N 3.34Å; A103-Q105 PolarHBondContact O-N 3.34Å; Q105-I108 PolarHBondContact O-N 2.9Å; Q105-L109 WeakPolarHBondContact O-CG 3.34Å; Q105-L109 PolarHBondContact O-N 3.35Å
106	G	78.3	Confident	84.4	Confident	23 Å²	23	43.6 Å²	43.6	24%	0.237	24%	0.242	C	C	.	.	H	α-helix	trans	-61.5	-42.3	176	0	0	0	0	0	112.7	S102 A103 T104 G110	S102-G106 PolarHBondContact O-N 2.98Å; A103-G106 PolarHBondContact O-N 3.35Å; A103-G106 VanDerWaalsContact O-N 3.15Å; T104-G106 VanDerWaalsContact C-N 3.31Å; T104-G106 PolarHBondContact O-N 3.46Å; G106-G110 PolarHBondContact O-N 2.88Å
107	W	84.6	Confident	85.3	Confident	149 Å²	149	43.7 Å²	43.7	56%	0.564	23%	0.233	S	C	*	.	H	α-helix	trans	-64.8	-42.7	175.2	-77	113.2	0	0	0	112.8	A103 T104 G110 S111 Y114 I162	A103-W107 PolarHBondContact O-N 3.28Å; T104-W107 PolarHBondContact O-N 3.47Å; W107-G110 PolarHBondContact O-N 2.86Å; W107-S111 VanDerWaalsContact O-CB 3.25Å; W107-S111 WeakPolarHBondContact O-CB 3.48Å; W107-S111 PolarHBondContact O-N 3.48Å; W107-Y114 HydrophobicContact CZ3-CE2 4.27Å; W107-Y114 AromaticContact CZ3-CZ 3.99Å; W107-Y114 WeakPolarHBondContact CZ3-OH 3.4Å; W107-I162 HydrophobicContact CB-CD1 4.1Å
108	I	87.9	Confident	85.8	Confident	0 Å²	0	46.5 Å²	46.5	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-61.8	-51.3	177.3	-66.3	162.1	0	0	0	110.2	L57 M61 W100 T104 Q105 G110 S111 A158 L161 I162	L57-I108 HydrophobicContact CD2-CG2 3.87Å; M61-I108 HydrophobicContact CE-CB 4.07Å; M61-I108 HydrophobicContact CE-CD1 4.37Å; M61-I108 HydrophobicContact CE-CG2 3.69Å; W100-I108 HydrophobicContact CD2-CD1 3.94Å; W100-I108 HydrophobicContact CE3-CD1 3.75Å; W100-I108 HydrophobicContact CH2-CD1 4.4Å; W100-I108 HydrophobicContact CZ3-CD1 3.99Å; T104-I108 HydrophobicContact CG2-CD1 3.85Å; T104-I108 HydrophobicContact CG2-CG1 4.36Å; T104-I108 VanDerWaalsContact O-CG1 3.32Å; T104-I108 WeakPolarHBondContact O-CG1 3.2Å; T104-I108 PolarHBondContact O-N 3.46Å; Q105-I108 PolarHBondContact O-N 2.9Å; I108-G110 VanDerWaalsContact C-N 3.35Å; I108-G110 PolarHBondContact O-N 3.5Å; I108-S111 PolarHBondContact O-N 2.75Å; I108-S111 PolarHBondContact O-OG 3.13Å; I108-A158 HydrophobicContact CD1-CB 4.22Å; I108-L161 HydrophobicContact CD1-CD2 4.13Å; I108-L161 HydrophobicContact CG1-CD2 4.45Å; I108-L161 HydrophobicContact CG2-CD2 3.75Å; I108-L161 HydrophobicContact CG2-CG 3.86Å; I108-I162 HydrophobicContact CB-CG1 4.42Å; I108-I162 HydrophobicContact CG1-CD1 4.24Å; I108-I162 HydrophobicContact CG1-CG1 3.77Å
109	L	81.9	Confident	86	Confident	49 Å²	49	45.9 Å²	45.9	26%	0.257	25%	0.245	S	C	.	.	H	α-helix	trans	-64	-39.9	179.1	-70	167.4	0	0	0	112.1	L57 M61 Q105	L57-L109 HydrophobicContact CD2-CD2 3.94Å; L57-L109 HydrophobicContact CG-CD2 4.06Å; M61-L109 HydrophobicContact CE-CD2 4.4Å; M61-L109 HydrophobicContact CE-CG 4.26Å; Q105-L109 WeakPolarHBondContact O-CG 3.34Å; Q105-L109 PolarHBondContact O-N 3.35Å
110	G	82.6	Confident	86.2	Confident	7 Å²	7	39.7 Å²	39.7	7%	0.072	21%	0.212	C	C	.	.	H	α-helix	trans	-72.7	-31.7	-178.7	0	0	0	0	0	114.1	G106 W107 I108 F112 F113 Y114	G106-G110 PolarHBondContact O-N 2.88Å; W107-G110 PolarHBondContact O-N 2.86Å; I108-G110 VanDerWaalsContact C-N 3.35Å; I108-G110 PolarHBondContact O-N 3.5Å; G110-F112 PolarHBondContact O-N 2.97Å; G110-F112 VanDerWaalsContact O-N 3.11Å; G110-F113 PolarHBondContact O-N 2.92Å; G110-Y114 VanDerWaalsContact O-CD2 3.24Å; G110-Y114 WeakPolarHBondContact O-CD2 3.36Å
111	S	89.3	Confident	86.4	Confident	6 Å²	6	41.4 Å²	41.4	4%	0.042	22%	0.223	C	C	.	.	H	α-helix	trans	-52.7	-35.3	-174.5	63.8	0	0	0	0	114.1	W107 I108 F113 Y114 G115 I162 R165	W107-S111 VanDerWaalsContact O-CB 3.25Å; W107-S111 WeakPolarHBondContact O-CB 3.48Å; W107-S111 PolarHBondContact O-N 3.48Å; I108-S111 PolarHBondContact O-N 2.75Å; I108-S111 PolarHBondContact O-OG 3.13Å; S111-F113 VanDerWaalsContact C-N 3.31Å; S111-F113 PolarHBondContact O-N 3.19Å; S111-Y114 PolarHBondContact O-N 2.9Å; S111-G115 PolarHBondContact O-N 3.26Å; S111-I162 PolarHBondContact OG-O 2.98Å; S111-R165 WeakPolarHBondContact OG-CB 3.41Å
112	F	90.8	Very high	86.8	Confident	9 Å²	9	40.2 Å²	40.2	4%	0.039	22%	0.22	C	C	.	.	H	α-helix	trans	-53.1	-46.3	173.5	174.6	-89.5	0	0	0	112.4	R54 G110 Y114 G115 Y116 R165 E168 G169 E172	R54-F112 HydrophobicContact CG-CE1 4.08Å; R54-F112 HydrophobicContact CG-CE2 4.49Å; R54-F112 HydrophobicContact CG-CZ 4.04Å; G110-F112 PolarHBondContact O-N 2.97Å; G110-F112 VanDerWaalsContact O-N 3.11Å; F112-Y114 VanDerWaalsContact C-N 3.31Å; F112-Y114 PolarHBondContact O-N 3.44Å; F112-G115 PolarHBondContact O-N 3.24Å; F112-Y116 AromaticContact CE1-CD2 3.96Å; F112-Y116 HydrophobicContact CE1-CD2 3.96Å; F112-Y116 HydrophobicContact CE1-CG 4.15Å; F112-Y116 AromaticContact CZ-CD2 3.93Å; F112-Y116 HydrophobicContact CZ-CD2 3.93Å; F112-Y116 HydrophobicContact CZ-CE2 4.49Å; F112-Y116 WeakPolarHBondContact O-CB 3.4Å; F112-Y116 PolarHBondContact O-N 3.23Å; F112-R165 WeakPolarHBondContact CA-O 3.36Å; F112-E168 HydrophobicContact CD2-CB 4.16Å; F112-E168 HydrophobicContact CE2-CB 4.36Å; F112-G169 WeakPolarHBondContact O-CA 3.48Å; F112-E172 HydrophobicContact CE2-CB 4.16Å; F112-E172 WeakPolarHBondContact CE2-OE2 3.49Å; F112-E172 HydrophobicContact CZ-CB 4Å; F112-E172 HydrophobicContact CZ-CG 4.28Å; F112-E172 WeakPolarHBondContact CZ-OE2 3.45Å
113	F	88.1	Confident	87.5	Confident	9 Å²	9	37.2 Å²	37.2	4%	0.039	20%	0.199	C	C	.	.	H	α-helix	trans	-68.8	-29.3	-176.4	-67.9	-76.8	0	0	0	112.9	G110 S111 Y116 I117 Y304 G435 M436	G110-F113 PolarHBondContact O-N 2.92Å; S111-F113 VanDerWaalsContact C-N 3.31Å; S111-F113 PolarHBondContact O-N 3.19Å; F113-Y116 PolarHBondContact O-N 2.72Å; F113-I117 PolarHBondContact O-N 3.16Å; F113-Y304 HydrophobicContact CE1-CD1 4.07Å; F113-Y304 HydrophobicContact CE1-CD2 4.38Å; F113-Y304 AromaticContact CE1-CE1 3.83Å; F113-Y304 HydrophobicContact CE1-CE1 3.83Å; F113-Y304 HydrophobicContact CE1-CE2 4.14Å; F113-Y304 HydrophobicContact CE1-CG 4.36Å; F113-Y304 AromaticContact CE1-CZ 3.87Å; F113-Y304 AromaticContact CZ-CD1 3.95Å; F113-Y304 HydrophobicContact CZ-CD1 3.95Å; F113-Y304 HydrophobicContact CZ-CE1 4.11Å; F113-Y304 HydrophobicContact CZ-CG 4.27Å; F113-G435 WeakPolarHBondContact CD2-O 3.3Å; F113-G435 WeakPolarHBondContact CE2-O 3.23Å; F113-M436 HydrophobicContact CB-CG 3.37Å; F113-M436 HydrophobicContact CB-SD 4.44Å; F113-M436 HydrophobicContact CG-CG 4.31Å
114	Y	89.8	Confident	87.7	Confident	98 Å²	98	34.9 Å²	34.9	38%	0.384	18%	0.18	S	C	.	.	H	α-helix	trans	-66	-37.8	174.3	-65.8	-91.3	0	0	0	112	W107 G110 S111 F112 I117 M436	W107-Y114 HydrophobicContact CZ3-CE2 4.27Å; W107-Y114 AromaticContact CZ3-CZ 3.99Å; W107-Y114 WeakPolarHBondContact CZ3-OH 3.4Å; G110-Y114 VanDerWaalsContact O-CD2 3.24Å; G110-Y114 WeakPolarHBondContact O-CD2 3.36Å; S111-Y114 PolarHBondContact O-N 2.9Å; F112-Y114 VanDerWaalsContact C-N 3.31Å; F112-Y114 PolarHBondContact O-N 3.44Å; Y114-I117 WeakPolarHBondContact O-CG2 3.43Å; Y114-M436 HydrophobicContact CD1-CE 3.14Å; Y114-M436 HydrophobicContact CD2-CE 4.16Å; Y114-M436 HydrophobicContact CE1-CE 3.14Å; Y114-M436 HydrophobicContact CE2-CE 4.2Å; Y114-M436 HydrophobicContact CG-CE 3.68Å
115	G	91.6	Very high	87.8	Confident	4 Å²	4	37.1 Å²	37.1	4%	0.041	19%	0.185	C	C	.	.	H	α-helix	trans	-70.4	-41.8	171.8	0	0	0	0	0	112.2	S111 F112 I117 L118 A166	S111-G115 PolarHBondContact O-N 3.26Å; F112-G115 PolarHBondContact O-N 3.24Å; G115-I117 PolarHBondContact O-N 3.44Å; G115-L118 WeakPolarHBondContact O-CB 3.46Å; G115-L118 PolarHBondContact O-N 3.13Å; G115-A166 WeakPolarHBondContact CA-O 2.93Å
116	Y	91.8	Very high	88.1	Confident	1 Å²	1	39.1 Å²	39.1	0%	0.004	20%	0.196	C	C	.	.	H	α-helix	trans	-61.9	-43.4	-177.1	-168.4	-101.9	0	0	0	113.3	R54 F112 F113 L118 T119 Q120 G169 E172 G173 F176 N428 T432	R54-Y116 VanDerWaalsContact NH2-CZ 3.32Å; R54-Y116 PolarHBondContact NH2-OH 3.06Å; F112-Y116 AromaticContact CE1-CD2 3.96Å; F112-Y116 HydrophobicContact CE1-CD2 3.96Å; F112-Y116 HydrophobicContact CE1-CG 4.15Å; F112-Y116 AromaticContact CZ-CD2 3.93Å; F112-Y116 HydrophobicContact CZ-CD2 3.93Å; F112-Y116 HydrophobicContact CZ-CE2 4.49Å; F112-Y116 WeakPolarHBondContact O-CB 3.4Å; F112-Y116 PolarHBondContact O-N 3.23Å; F113-Y116 PolarHBondContact O-N 2.72Å; Y116-L118 VanDerWaalsContact C-N 3.29Å; Y116-L118 PolarHBondContact O-N 2.91Å; Y116-T119 PolarHBondContact O-N 3.32Å; Y116-Q120 VanDerWaalsContact CD1-NE2 3.34Å; Y116-Q120 WeakPolarHBondContact O-CG 3.14Å; Y116-G169 VanDerWaalsContact CA-O 3.25Å; Y116-G169 WeakPolarHBondContact CA-O 3.15Å; Y116-E172 HydrophobicContact CD2-CB 4.16Å; Y116-E172 HydrophobicContact CE2-CB 4.23Å; Y116-E172 HydrophobicContact CE2-CG 4.32Å; Y116-G173 VanDerWaalsContact CE2-CA 3.43Å; Y116-F176 WeakPolarHBondContact OH-CD2 3.43Å; Y116-F176 WeakPolarHBondContact OH-CE2 3.26Å; Y116-N428 PolarHBondContact OH-ND2 3.38Å; Y116-T432 HydrophobicContact CD1-CG2 3.32Å; Y116-T432 HydrophobicContact CE1-CG2 3.27Å
117	I	91.6	Very high	88.5	Confident	42 Å²	42	38.1 Å²	38.1	22%	0.215	19%	0.186	C	C	.	.	H	α-helix	trans	-66.1	-32	-178.9	-162.4	168.6	0	0	0	112.3	F113 Y114 G115 T119 T429 I433 M436	F113-I117 PolarHBondContact O-N 3.16Å; Y114-I117 WeakPolarHBondContact O-CG2 3.43Å; G115-I117 PolarHBondContact O-N 3.44Å; I117-T119 VanDerWaalsContact C-N 3.3Å; I117-T119 PolarHBondContact O-N 3.33Å; I117-T429 HydrophobicContact CD1-CG2 3.99Å; I117-T429 HydrophobicContact CG1-CG2 3.51Å; I117-I433 HydrophobicContact CD1-CG1 3.89Å; I117-M436 HydrophobicContact CD1-SD 4.12Å; I117-M436 HydrophobicContact CG2-SD 4.41Å
118	L	92.5	Very high	88.3	Confident	117 Å²	117	33.9 Å²	33.9	61%	0.613	19%	0.188	S	C	*	.	H	α-helix	trans	-63.1	-35.4	-177.2	-177.8	64.3	0	0	0	112.3	G115 Y116 P122	G115-L118 WeakPolarHBondContact O-CB 3.46Å; G115-L118 PolarHBondContact O-N 3.13Å; Y116-L118 VanDerWaalsContact C-N 3.29Å; Y116-L118 PolarHBondContact O-N 2.91Å; L118-P122 VanDerWaalsContact O-CD 3.29Å; L118-P122 WeakPolarHBondContact O-CD 3.48Å; L118-P122 WeakPolarHBondContact O-CG 3.19Å
119	T	92.4	Very high	88.1	Confident	21 Å²	21	42.7 Å²	42.7	13%	0.129	22%	0.221	C	C	.	.	H	α-helix	trans	-101	-3.4	-172	58	0	0	0	0	114.5	Y116 I117 G123 V170 G173	Y116-T119 PolarHBondContact O-N 3.32Å; I117-T119 VanDerWaalsContact C-N 3.3Å; I117-T119 PolarHBondContact O-N 3.33Å; T119-G123 WeakPolarHBondContact O-CA 3.46Å; T119-G123 PolarHBondContact O-N 3.11Å; T119-V170 HydrophobicContact CG2-CB 4.24Å; T119-V170 HydrophobicContact CG2-CG1 3.66Å; T119-V170 WeakPolarHBondContact CG2-O 3.4Å; T119-V170 PolarHBondContact OG1-O 2.92Å; T119-G173 VanDerWaalsContact OG1-CA 3.25Å; T119-G173 WeakPolarHBondContact OG1-CA 3.26Å
120	Q	89.7	Confident	88.2	Confident	0 Å²	0	44.3 Å²	44.3	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-61.3	-58.5	179.4	-71.7	-56.8	-35.1	0	0	113.6	Y116 G123 G124 G173 P177 N428 T429	Y116-Q120 VanDerWaalsContact CD1-NE2 3.34Å; Y116-Q120 WeakPolarHBondContact O-CG 3.14Å; Q120-G123 PolarHBondContact O-N 3.37Å; Q120-G124 PolarHBondContact O-N 3.19Å; Q120-G124 VanDerWaalsContact O-N 3.13Å; Q120-G173 PolarHBondContact NE2-O 3.38Å; Q120-G173 PolarHBondContact OE1-O 3.29Å; Q120-P177 WeakPolarHBondContact O-CG 3.29Å; Q120-N428 PolarHBondContact NE2-ND2 3.47Å; Q120-N428 PolarHBondContact OE1-ND2 2.92Å; Q120-T429 WeakPolarHBondContact CB-OG1 3.26Å
121	I	88.6	Confident	88.4	Confident	66 Å²	66	44.8 Å²	44.8	34%	0.338	24%	0.24	S	C	.	.	H	α-helix	trans	-68	-49.4	-178.9	-51.3	-179.6	0	0	0	110.8	G123 G124 Y125 W280 T429	I121-G123 VanDerWaalsContact C-N 3.26Å; I121-G123 PolarHBondContact O-N 3.07Å; I121-G124 PolarHBondContact O-N 3.21Å; I121-Y125 PolarHBondContact O-N 3.01Å; I121-W280 HydrophobicContact CG2-CH2 4.45Å; I121-T429 HydrophobicContact CD1-CG2 4.25Å; I121-T429 HydrophobicContact CG1-CG2 4.41Å; I121-T429 VanDerWaalsContact CG1-OG1 3.22Å; I121-T429 WeakPolarHBondContact CG1-OG1 3.45Å
122	P	91	Very high	88.5	Confident	63 Å²	63	44.8 Å²	44.8	41%	0.409	24%	0.241	S	C	.	.	H	α-helix	trans	-60.6	-37.6	176.1	-23.2	35.7	0	0	0	112.2	L118 G124 Y125 L126	L118-P122 VanDerWaalsContact O-CD 3.29Å; L118-P122 WeakPolarHBondContact O-CD 3.48Å; L118-P122 WeakPolarHBondContact O-CG 3.19Å; P122-G124 PolarHBondContact O-N 2.91Å; P122-Y125 PolarHBondContact O-N 3.42Å; P122-L126 VanDerWaalsContact O-CB 3.31Å; P122-L126 WeakPolarHBondContact O-CB 3.38Å; P122-L126 VanDerWaalsContact O-CG 3.26Å; P122-L126 WeakPolarHBondContact O-CG 3.31Å; P122-L126 PolarHBondContact O-N 3.5Å
123	G	88.8	Confident	88.7	Confident	0 Å²	0	45.1 Å²	45.1	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-61.1	-42.7	178.5	0	0	0	0	0	112.6	T119 Q120 I121 Y125 L126 A127 L135	T119-G123 WeakPolarHBondContact O-CA 3.46Å; T119-G123 PolarHBondContact O-N 3.11Å; Q120-G123 PolarHBondContact O-N 3.37Å; I121-G123 VanDerWaalsContact C-N 3.26Å; I121-G123 PolarHBondContact O-N 3.07Å; G123-Y125 VanDerWaalsContact C-N 3.34Å; G123-Y125 PolarHBondContact O-N 2.73Å; G123-L126 PolarHBondContact O-N 3.46Å; G123-A127 WeakPolarHBondContact O-CB 3.2Å; G123-A127 PolarHBondContact O-N 3.38Å; G123-L135 VanDerWaalsContact O-CD2 3.27Å; G123-L135 WeakPolarHBondContact O-CD2 3.24Å
124	G	83.8	Confident	89	Confident	4 Å²	4	49.7 Å²	49.7	4%	0.041	26%	0.259	C	S	.	.	H	α-helix	trans	-62.4	-39.2	174.6	0	0	0	0	0	113.2	Q120 I121 P122	Q120-G124 PolarHBondContact O-N 3.19Å; Q120-G124 VanDerWaalsContact O-N 3.13Å; I121-G124 PolarHBondContact O-N 3.21Å; P122-G124 PolarHBondContact O-N 2.91Å
125	Y	85.8	Confident	89.2	Confident	84 Å²	84	46.5 Å²	46.5	33%	0.329	25%	0.249	S	C	.	.	H	α-helix	trans	-71.7	-45.5	176.4	179.4	-99.2	0	0	0	112.7	I121 P122 G123 A127 G128 R129 I278	I121-Y125 PolarHBondContact O-N 3.01Å; P122-Y125 PolarHBondContact O-N 3.42Å; G123-Y125 VanDerWaalsContact C-N 3.34Å; G123-Y125 PolarHBondContact O-N 2.73Å; Y125-A127 VanDerWaalsContact C-N 3.33Å; Y125-A127 PolarHBondContact O-N 3.47Å; Y125-G128 PolarHBondContact O-N 3.11Å; Y125-R129 PolarHBondContact OH-NE 3.18Å; Y125-R129 PolarHBondContact OH-NH1 3.37Å; Y125-R129 PolarHBondContact OH-NH2 3.43Å; Y125-R129 VanDerWaalsContact OH-NH2 3.14Å; Y125-I278 HydrophobicContact CD2-CD1 3.99Å; Y125-I278 HydrophobicContact CE2-CD1 3.95Å
126	L	89.1	Confident	89.4	Confident	70 Å²	70	46.4 Å²	46.4	37%	0.366	25%	0.247	S	C	.	.	H	α-helix	trans	-66.4	-34.9	179.4	-72.6	171.8	0	0	0	111.7	P122 G123 G128 R129 C130 L135	P122-L126 VanDerWaalsContact O-CB 3.31Å; P122-L126 WeakPolarHBondContact O-CB 3.38Å; P122-L126 VanDerWaalsContact O-CG 3.26Å; P122-L126 WeakPolarHBondContact O-CG 3.31Å; P122-L126 PolarHBondContact O-N 3.5Å; G123-L126 PolarHBondContact O-N 3.46Å; L126-G128 PolarHBondContact O-N 3.34Å; L126-R129 PolarHBondContact O-N 3.42Å; L126-R129 VanDerWaalsContact O-N 3.08Å; L126-C130 WeakPolarHBondContact O-CB 3.41Å; L126-C130 PolarHBondContact O-N 3.19Å; L126-L135 HydrophobicContact CB-CD2 4.01Å
127	A	87.3	Confident	89.6	Confident	2 Å²	2	46.3 Å²	46.3	2%	0.017	25%	0.247	C	C	.	.	H	α-helix	trans	-57.5	-39.2	176.9	0	0	0	0	0	111.9	G123 Y125 R129 G131 A132 L135 A178 T181	G123-A127 WeakPolarHBondContact O-CB 3.2Å; G123-A127 PolarHBondContact O-N 3.38Å; Y125-A127 VanDerWaalsContact C-N 3.33Å; Y125-A127 PolarHBondContact O-N 3.47Å; A127-R129 VanDerWaalsContact C-N 3.33Å; A127-R129 PolarHBondContact O-N 3.24Å; A127-G131 CarbonylContact O-C 3.59Å; A127-A132 HydrophobicContact CB-CB 4.47Å; A127-A132 PolarHBondContact O-N 3.1Å; A127-L135 HydrophobicContact CB-CD2 3.78Å; A127-A178 HydrophobicContact CB-CB 4.28Å; A127-T181 HydrophobicContact CB-CG2 4.07Å
128	G	79.6	Confident	89.9	Confident	59 Å²	59	49.9 Å²	49.9	61%	0.608	26%	0.261	S	S	*	.	H	α-helix	trans	-72.2	-22	178.7	0	0	0	0	0	114.3	Y125 L126	Y125-G128 PolarHBondContact O-N 3.11Å; L126-G128 PolarHBondContact O-N 3.34Å
129	R	83.4	Confident	90	Very high	186 Å²	186	44.6 Å²	44.6	70%	0.702	24%	0.235	S	C	*	.	H	α-helix	trans	-105.3	-39.7	-177.3	-73.2	-164.4	172.2	-166.1	-0.9	114.6	Y125 L126 A127	Y125-R129 PolarHBondContact OH-NE 3.18Å; Y125-R129 PolarHBondContact OH-NH1 3.37Å; Y125-R129 PolarHBondContact OH-NH2 3.43Å; Y125-R129 VanDerWaalsContact OH-NH2 3.14Å; L126-R129 PolarHBondContact O-N 3.42Å; L126-R129 VanDerWaalsContact O-N 3.08Å; A127-R129 VanDerWaalsContact C-N 3.33Å; A127-R129 PolarHBondContact O-N 3.24Å
130	C	84.6	Confident	90.2	Very high	82 Å²	82	43.7 Å²	43.7	55%	0.554	23%	0.229	S	C	*	.	H	α-helix	trans	-97.8	-1	-172	-55.6	0	0	0	0	113.1	L126	L126-C130 WeakPolarHBondContact O-CB 3.41Å; L126-C130 PolarHBondContact O-N 3.19Å
131	G	87.6	Confident	90.6	Very high	17 Å²	17	45.3 Å²	45.3	18%	0.175	24%	0.238	C	C	.	.			trans	88.4	125.6	-172.8	0	0	0	0	0	111.6	A127 K133 L135	A127-G131 CarbonylContact O-C 3.59Å; G131-K133 VanDerWaalsContact C-N 3.32Å; G131-K133 PolarHBondContact O-N 3.02Å; G131-L135 PolarHBondContact O-N 3.48Å
132	A	91.4	Very high	91	Very high	6 Å²	6	43 Å²	43	5%	0.05	23%	0.231	C	C	.	.	H	α-helix	trans	-67.5	-33.3	-178.3	0	0	0	0	0	112.2	A127 M136 A178 T181 M182 D247	A127-A132 HydrophobicContact CB-CB 4.47Å; A127-A132 PolarHBondContact O-N 3.1Å; A132-M136 WeakPolarHBondContact O-CB 3.32Å; A132-M136 PolarHBondContact O-N 3.16Å; A132-M136 VanDerWaalsContact O-N 3.09Å; A132-A178 WeakPolarHBondContact CB-O 3.44Å; A132-T181 HydrophobicContact CB-CG2 4.25Å; A132-M182 HydrophobicContact CB-CB 4.15Å; A132-M182 HydrophobicContact CB-CE 3.83Å; A132-D247 PolarHBondContact N-OD1 2.81Å
133	K	93.8	Very high	91.3	Very high	16 Å²	16	40.1 Å²	40.1	7%	0.07	21%	0.212	C	C	.	.	H	α-helix	trans	-57	-56.9	178.2	174.3	-168.3	172.3	170.5	0	111	G131 G137 M182 W241 A242 V245 D247	G131-K133 VanDerWaalsContact C-N 3.32Å; G131-K133 PolarHBondContact O-N 3.02Å; K133-G137 PolarHBondContact O-N 3.43Å; K133-M182 HydrophobicContact CB-CE 3.79Å; K133-M182 VanDerWaalsContact N-CE 3.3Å; K133-W241 PolarHBondContact O-NE1 3.01Å; K133-A242 WeakPolarHBondContact CE-O 3.39Å; K133-A242 PolarHBondContact NZ-O 3.39Å; K133-V245 WeakPolarHBondContact CD-O 3.37Å; K133-V245 WeakPolarHBondContact CE-O 3.35Å; K133-V245 HydrophobicContact CG-CG1 4.24Å; K133-V245 PolarHBondContact NZ-O 3.29Å; K133-D247 WeakPolarHBondContact CB-OD1 3.22Å; K133-D247 PolarHBondContact N-OD1 3.47Å
134	W	94.8	Very high	91.7	Very high	105 Å²	105	40.1 Å²	40.1	40%	0.398	21%	0.212	S	C	.	.	H	α-helix	trans	-71.7	-36.9	-173.5	-71.5	116.1	0	0	0	111.5	G137 F138 F238 A242	W134-G137 PolarHBondContact O-N 2.82Å; W134-F138 HydrophobicContact CB-CD2 4.1Å; W134-F138 HydrophobicContact CB-CE2 4.01Å; W134-F138 HydrophobicContact CD2-CE2 4.17Å; W134-F138 HydrophobicContact CE3-CD2 4.33Å; W134-F138 AromaticContact CE3-CE2 3.64Å; W134-F138 HydrophobicContact CE3-CE2 3.64Å; W134-F138 AromaticContact CE3-CZ 3.78Å; W134-F138 HydrophobicContact CE3-CZ 3.78Å; W134-F138 HydrophobicContact CG-CE2 4.36Å; W134-F138 HydrophobicContact CZ3-CE2 4.46Å; W134-F138 HydrophobicContact CZ3-CZ 4.16Å; W134-F138 WeakPolarHBondContact O-CB 3.29Å; W134-F138 WeakPolarHBondContact O-CD2 3.39Å; W134-F138 PolarHBondContact O-N 3.31Å; W134-F238 HydrophobicContact CZ3-CZ 4.38Å; W134-A242 HydrophobicContact CH2-CB 4.21Å; W134-A242 HydrophobicContact CZ3-CB 4.14Å
135	L	95.1	Very high	92.4	Very high	32 Å²	32	43.9 Å²	43.9	17%	0.168	23%	0.231	C	C	.	.	H	α-helix	trans	-61.2	-47.2	176.7	-172.6	65.1	0	0	0	111.8	G123 L126 A127 G131 G139 V174 A178	G123-L135 VanDerWaalsContact O-CD2 3.27Å; G123-L135 WeakPolarHBondContact O-CD2 3.24Å; L126-L135 HydrophobicContact CB-CD2 4.01Å; A127-L135 HydrophobicContact CB-CD2 3.78Å; G131-L135 PolarHBondContact O-N 3.48Å; L135-G139 PolarHBondContact O-N 3.39Å; L135-G139 VanDerWaalsContact O-N 3.07Å; L135-V174 HydrophobicContact CD1-CB 4.21Å; L135-V174 HydrophobicContact CD1-CG1 4.23Å; L135-V174 HydrophobicContact CD1-CG2 4.19Å; L135-V174 HydrophobicContact CD2-CB 4.18Å; L135-V174 HydrophobicContact CG-CB 3.91Å; L135-V174 HydrophobicContact CG-CG1 4.43Å; L135-V174 HydrophobicContact CG-CG2 3.99Å; L135-V174 WeakPolarHBondContact O-CG2 3.36Å; L135-A178 HydrophobicContact CB-CB 4.48Å; L135-A178 HydrophobicContact CD2-CB 4.36Å
136	M	95.2	Very high	92.9	Very high	1 Å²	1	42.8 Å²	42.8	1%	0.005	23%	0.228	C	C	.	.	H	α-helix	trans	-63.8	-46.2	174.5	-178	175.9	173.8	0	0	111.4	F47 A132 G139 V140 A178 M179 W237 W241	F47-M136 HydrophobicContact CE2-CE 4.32Å; A132-M136 WeakPolarHBondContact O-CB 3.32Å; A132-M136 PolarHBondContact O-N 3.16Å; A132-M136 VanDerWaalsContact O-N 3.09Å; M136-G139 PolarHBondContact O-N 3.24Å; M136-V140 WeakPolarHBondContact O-CG2 3.5Å; M136-V140 PolarHBondContact O-N 3Å; M136-A178 HydrophobicContact CB-CB 3.94Å; M136-M179 HydrophobicContact SD-CB 4.48Å; M136-M179 HydrophobicContact SD-SD 3.95Å; M136-W237 HydrophobicContact CE-CH2 3.92Å; M136-W237 HydrophobicContact CE-CZ2 3.97Å; M136-W237 HydrophobicContact CG-CH2 4.31Å; M136-W241 HydrophobicContact CB-CZ2 4.4Å; M136-W241 HydrophobicContact CE-CH2 4.33Å; M136-W241 HydrophobicContact CG-CZ2 4.37Å; M136-W241 HydrophobicContact SD-CH2 3.73Å; M136-W241 HydrophobicContact SD-CZ2 3.68Å; M136-W241 HydrophobicContact SD-CZ3 4.47Å
137	G	96.3	Very high	93.3	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-59	-53.6	-178.2	0	0	0	0	0	112.8	K133 W134 G139 V140 L141 F238	K133-G137 PolarHBondContact O-N 3.43Å; W134-G137 PolarHBondContact O-N 2.82Å; G137-G139 VanDerWaalsContact C-N 3.31Å; G137-G139 PolarHBondContact O-N 2.94Å; G137-V140 PolarHBondContact O-N 3.09Å; G137-L141 WeakPolarHBondContact O-CB 3.49Å; G137-L141 PolarHBondContact O-N 3.09Å; G137-F238 VanDerWaalsContact C-CD2 3.49Å; G137-F238 WeakPolarHBondContact O-CD2 3.48Å
138	F	96.3	Very high	93.7	Very high	116 Å²	116	41.8 Å²	41.8	51%	0.509	22%	0.222	S	C	.	.	H	α-helix	trans	-67.1	-31.7	178.9	-69.8	-54.6	0	0	0	112.8	W134 L141 G142 F238	W134-F138 HydrophobicContact CB-CD2 4.1Å; W134-F138 HydrophobicContact CB-CE2 4.01Å; W134-F138 HydrophobicContact CD2-CE2 4.17Å; W134-F138 HydrophobicContact CE3-CD2 4.33Å; W134-F138 AromaticContact CE3-CE2 3.64Å; W134-F138 HydrophobicContact CE3-CE2 3.64Å; W134-F138 AromaticContact CE3-CZ 3.78Å; W134-F138 HydrophobicContact CE3-CZ 3.78Å; W134-F138 HydrophobicContact CG-CE2 4.36Å; W134-F138 HydrophobicContact CZ3-CE2 4.46Å; W134-F138 HydrophobicContact CZ3-CZ 4.16Å; W134-F138 WeakPolarHBondContact O-CB 3.29Å; W134-F138 WeakPolarHBondContact O-CD2 3.39Å; W134-F138 PolarHBondContact O-N 3.31Å; F138-L141 HydrophobicContact CD1-CD2 4.35Å; F138-G142 PolarHBondContact O-N 3.49Å; F138-F238 HydrophobicContact CD1-CE2 4.01Å; F138-F238 AromaticContact CD1-CZ 3.99Å; F138-F238 HydrophobicContact CD1-CZ 3.99Å; F138-F238 HydrophobicContact CE1-CE2 4.19Å; F138-F238 AromaticContact CE1-CZ 3.78Å; F138-F238 HydrophobicContact CE1-CZ 3.78Å
139	G	96.2	Very high	94.5	Very high	7 Å²	7	42.8 Å²	42.8	7%	0.072	21%	0.213	C	C	.	.	H	α-helix	trans	-58.3	-53.8	171.9	0	0	0	0	0	112	L135 M136 G137 L141 G142 T143 G171	L135-G139 PolarHBondContact O-N 3.39Å; L135-G139 VanDerWaalsContact O-N 3.07Å; M136-G139 PolarHBondContact O-N 3.24Å; G137-G139 VanDerWaalsContact C-N 3.31Å; G137-G139 PolarHBondContact O-N 2.94Å; G139-L141 PolarHBondContact O-N 3.27Å; G139-G142 PolarHBondContact O-N 3.23Å; G139-T143 PolarHBondContact O-N 3.29Å; G139-T143 PolarHBondContact O-OG1 3.4Å; G139-T143 VanDerWaalsContact O-OG1 3.11Å; G139-G171 CarbonylContact C-O 3.6Å; G139-G171 WeakPolarHBondContact CA-O 3.38Å; G139-G171 CarbonylContact O-C 3.5Å
140	V	96.9	Very high	95.1	Very high	1 Å²	1	34 Å²	34	1%	0.006	18%	0.18	C	C	.	.	H	α-helix	trans	-65.4	-39.6	178.8	178.9	0	0	0	0	112	V49 V50 M136 G137 T143 A144 T175 W237	V49-V140 HydrophobicContact CG1-CG1 4.13Å; V50-V140 HydrophobicContact CG2-CG1 4.46Å; V50-V140 HydrophobicContact CG2-CG2 3.62Å; M136-V140 WeakPolarHBondContact O-CG2 3.5Å; M136-V140 PolarHBondContact O-N 3Å; G137-V140 PolarHBondContact O-N 3.09Å; V140-T143 PolarHBondContact O-N 3.27Å; V140-A144 WeakPolarHBondContact O-CB 3.5Å; V140-A144 PolarHBondContact O-N 2.87Å; V140-T175 HydrophobicContact CG2-CG2 3.81Å; V140-W237 HydrophobicContact CB-CE3 3.97Å; V140-W237 HydrophobicContact CB-CH2 4.41Å; V140-W237 HydrophobicContact CB-CZ3 3.56Å; V140-W237 HydrophobicContact CG1-CD2 4.46Å; V140-W237 HydrophobicContact CG1-CE3 3.55Å; V140-W237 HydrophobicContact CG1-CZ3 3.7Å; V140-W237 HydrophobicContact CG2-CE3 4.4Å; V140-W237 HydrophobicContact CG2-CH2 4.08Å; V140-W237 HydrophobicContact CG2-CZ3 3.71Å
141	L	97.8	Very high	95.6	Very high	34 Å²	34	30.1 Å²	30.1	18%	0.178	15%	0.154	C	C	.	.	H	α-helix	trans	-60.4	-47	175.4	178.3	65.4	0	0	0	111.2	G137 F138 G139 A144 L145 V235 F238	G137-L141 WeakPolarHBondContact O-CB 3.49Å; G137-L141 PolarHBondContact O-N 3.09Å; F138-L141 HydrophobicContact CD1-CD2 4.35Å; G139-L141 PolarHBondContact O-N 3.27Å; L141-A144 PolarHBondContact O-N 3.42Å; L141-L145 HydrophobicContact CD1-CD1 4.29Å; L141-L145 HydrophobicContact CD1-CG 4.24Å; L141-L145 HydrophobicContact CG-CD1 4.13Å; L141-L145 HydrophobicContact CG-CG 4.45Å; L141-L145 VanDerWaalsContact O-CG 3.3Å; L141-L145 WeakPolarHBondContact O-CG 3.41Å; L141-L145 PolarHBondContact O-N 2.9Å; L141-V235 HydrophobicContact CD1-CG1 4.49Å; L141-V235 HydrophobicContact CD1-CG2 4.25Å; L141-F238 HydrophobicContact CB-CB 4.21Å; L141-F238 HydrophobicContact CB-CD1 4.36Å; L141-F238 HydrophobicContact CB-CD2 3.89Å; L141-F238 HydrophobicContact CB-CE2 4.34Å; L141-F238 HydrophobicContact CB-CG 3.88Å; L141-F238 HydrophobicContact CD1-CB 4.23Å; L141-F238 HydrophobicContact CD1-CD1 3.98Å; L141-F238 HydrophobicContact CD1-CG 4.12Å; L141-F238 HydrophobicContact CD2-CD1 3.86Å; L141-F238 HydrophobicContact CD2-CD2 4.43Å; L141-F238 HydrophobicContact CD2-CE1 3.72Å; L141-F238 HydrophobicContact CD2-CE2 4.29Å; L141-F238 HydrophobicContact CD2-CG 4.21Å; L141-F238 HydrophobicContact CD2-CZ 3.94Å; L141-F238 HydrophobicContact CG-CD1 4.29Å; L141-F238 HydrophobicContact CG-CG 4.29Å
142	G	96.9	Very high	95.9	Very high	18 Å²	18	34 Å²	34	19%	0.186	17%	0.17	C	C	.	.	H	α-helix	trans	-57.4	-50.7	176.9	0	0	0	0	0	111.3	F138 G139 A144 L145 F146	F138-G142 PolarHBondContact O-N 3.49Å; G139-G142 PolarHBondContact O-N 3.23Å; G142-A144 PolarHBondContact O-N 3.31Å; G142-L145 PolarHBondContact O-N 3.41Å; G142-F146 WeakPolarHBondContact O-CD2 3.43Å; G142-F146 WeakPolarHBondContact O-CG 3.27Å; G142-F146 PolarHBondContact O-N 2.64Å
143	T	97.1	Very high	96	Very high	2 Å²	2	34 Å²	34	1%	0.012	17%	0.17	C	C	.	.	H	α-helix	trans	-56.5	-47.8	175.9	-56.3	0	0	0	0	111.5	L53 G139 V140 L145 F146 T147 E168 E172	L53-T143 HydrophobicContact CB-CG2 4.36Å; L53-T143 HydrophobicContact CD1-CG2 4.12Å; G139-T143 PolarHBondContact O-N 3.29Å; G139-T143 PolarHBondContact O-OG1 3.4Å; G139-T143 VanDerWaalsContact O-OG1 3.11Å; V140-T143 PolarHBondContact O-N 3.27Å; T143-L145 PolarHBondContact O-N 3.49Å; T143-F146 PolarHBondContact O-N 3.48Å; T143-T147 PolarHBondContact O-N 2.92Å; T143-T147 PolarHBondContact O-OG1 3.41Å; T143-E168 HydrophobicContact CG2-CB 4.1Å; T143-E168 HydrophobicContact CG2-CG 4.36Å; T143-E168 PolarHBondContact OG1-O 2.95Å; T143-E172 HydrophobicContact CG2-CB 4.43Å; T143-E172 PolarHBondContact OG1-N 3.28Å; T143-E172 VanDerWaalsContact OG1-N 3.17Å
144	A	97.5	Very high	96	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-60.9	-42.2	179.7	0	0	0	0	0	112.8	L53 V140 L141 G142 T147 L148 V235	L53-A144 HydrophobicContact CD1-CB 4.19Å; V140-A144 WeakPolarHBondContact O-CB 3.5Å; V140-A144 PolarHBondContact O-N 2.87Å; L141-A144 PolarHBondContact O-N 3.42Å; G142-A144 PolarHBondContact O-N 3.31Å; A144-T147 PolarHBondContact O-N 3.46Å; A144-L148 WeakPolarHBondContact O-CG 3.44Å; A144-L148 PolarHBondContact O-N 3.31Å; A144-V235 HydrophobicContact CB-CG2 4.24Å
145	L	97.8	Very high	95.8	Very high	84 Å²	84	33.4 Å²	33.4	44%	0.44	18%	0.175	S	C	.	.	H	α-helix	trans	-65.4	-42.6	177	-68.6	176.1	0	0	0	111.9	L141 G142 T143 T147 L148 L149 V235	L141-L145 HydrophobicContact CD1-CD1 4.29Å; L141-L145 HydrophobicContact CD1-CG 4.24Å; L141-L145 HydrophobicContact CG-CD1 4.13Å; L141-L145 HydrophobicContact CG-CG 4.45Å; L141-L145 VanDerWaalsContact O-CG 3.3Å; L141-L145 WeakPolarHBondContact O-CG 3.41Å; L141-L145 PolarHBondContact O-N 2.9Å; G142-L145 PolarHBondContact O-N 3.41Å; T143-L145 PolarHBondContact O-N 3.49Å; L145-T147 VanDerWaalsContact C-N 3.31Å; L145-T147 PolarHBondContact O-N 3.44Å; L145-L148 HydrophobicContact CD2-CD1 4.46Å; L145-L148 WeakPolarHBondContact O-CB 3.25Å; L145-L148 PolarHBondContact O-N 2.85Å; L145-L149 WeakPolarHBondContact O-CG 3Å; L145-L149 PolarHBondContact O-N 3.41Å; L145-V235 HydrophobicContact CD2-CG2 4.22Å
146	F	97.3	Very high	95.7	Very high	60 Å²	60	36.9 Å²	36.9	26%	0.263	19%	0.194	S	C	.	.	H	α-helix	trans	-66.6	-33.7	175.4	-68.5	-51.9	0	0	0	112.2	G142 T143 L149 T150 V164 L167 E168	G142-F146 WeakPolarHBondContact O-CD2 3.43Å; G142-F146 WeakPolarHBondContact O-CG 3.27Å; G142-F146 PolarHBondContact O-N 2.64Å; T143-F146 PolarHBondContact O-N 3.48Å; F146-L149 HydrophobicContact CD1-CD1 4.21Å; F146-L149 CarbonylContact O-C 3.59Å; F146-L149 WeakPolarHBondContact O-CA 3.46Å; F146-L149 WeakPolarHBondContact O-CB 3.47Å; F146-L149 PolarHBondContact O-N 2.56Å; F146-L149 VanDerWaalsContact O-N 3.08Å; F146-T150 PolarHBondContact O-N 3.31Å; F146-T150 VanDerWaalsContact O-N 3.12Å; F146-V164 HydrophobicContact CB-CG1 4.03Å; F146-V164 VanDerWaalsContact O-CG1 3.23Å; F146-V164 WeakPolarHBondContact O-CG1 3.28Å; F146-L167 HydrophobicContact CD1-CB 4.26Å; F146-L167 HydrophobicContact CD1-CD1 4.25Å; F146-L167 HydrophobicContact CD2-CB 3.74Å; F146-L167 HydrophobicContact CE1-CB 4.22Å; F146-L167 HydrophobicContact CE1-CD1 3.75Å; F146-L167 HydrophobicContact CE2-CB 3.7Å; F146-L167 HydrophobicContact CG-CB 4.05Å; F146-L167 HydrophobicContact CZ-CB 3.96Å; F146-L167 HydrophobicContact CZ-CD1 3.91Å; F146-L167 HydrophobicContact CZ-CG 4.4Å; F146-E168 HydrophobicContact CB-CG 3.55Å
147	T	96.3	Very high	95.5	Very high	0 Å²	0	38 Å²	38	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-63.6	-41.7	172.1	-59.1	0	0	0	0	111.9	L53 T143 A144 L145 L149 T150 E168 F227	L53-T147 HydrophobicContact CD2-CG2 3.78Å; T143-T147 PolarHBondContact O-N 2.92Å; T143-T147 PolarHBondContact O-OG1 3.41Å; A144-T147 PolarHBondContact O-N 3.46Å; L145-T147 VanDerWaalsContact C-N 3.31Å; L145-T147 PolarHBondContact O-N 3.44Å; T147-L149 PolarHBondContact O-N 3.13Å; T147-T150 VanDerWaalsContact O-CB 3.24Å; T147-T150 WeakPolarHBondContact O-CB 3.34Å; T147-T150 PolarHBondContact O-N 2.9Å; T147-T150 PolarHBondContact O-OG1 2.98Å; T147-E168 WeakPolarHBondContact CA-OE1 3.46Å; T147-E168 WeakPolarHBondContact CB-OE1 3.3Å; T147-E168 PolarHBondContact N-OE1 3.06Å; T147-E168 VanDerWaalsContact N-OE1 3.16Å; T147-E168 PolarHBondContact OG1-OE1 3.47Å; T147-F227 HydrophobicContact CG2-CB 4.13Å; T147-F227 HydrophobicContact CG2-CD1 3.89Å; T147-F227 WeakPolarHBondContact O-CB 3.24Å
148	L	97.1	Very high	95.2	Very high	51 Å²	51	39 Å²	39	27%	0.267	21%	0.214	S	C	.	.	H	α-helix	trans	-60.2	-28.7	172.9	-66.9	175	0	0	0	112.9	A144 L145 Y228 V235	A144-L148 WeakPolarHBondContact O-CG 3.44Å; A144-L148 PolarHBondContact O-N 3.31Å; L145-L148 HydrophobicContact CD2-CD1 4.46Å; L145-L148 WeakPolarHBondContact O-CB 3.25Å; L145-L148 PolarHBondContact O-N 2.85Å; L148-Y228 HydrophobicContact CD2-CD1 4.21Å; L148-Y228 WeakPolarHBondContact CD2-O 3.47Å; L148-Y228 WeakPolarHBondContact O-CE1 3.07Å; L148-V235 HydrophobicContact CD1-CG2 4.36Å
149	L	96.2	Very high	95	Very high	81 Å²	81	37.2 Å²	37.2	42%	0.424	22%	0.215	S	C	.	.	H	α-helix	trans	-83.8	-10.2	177	-64.8	173.1	0	0	0	113.6	L145 F146 T147 L152 A153	L145-L149 WeakPolarHBondContact O-CG 3Å; L145-L149 PolarHBondContact O-N 3.41Å; F146-L149 HydrophobicContact CD1-CD1 4.21Å; F146-L149 CarbonylContact O-C 3.59Å; F146-L149 WeakPolarHBondContact O-CA 3.46Å; F146-L149 WeakPolarHBondContact O-CB 3.47Å; F146-L149 PolarHBondContact O-N 2.56Å; F146-L149 VanDerWaalsContact O-N 3.08Å; T147-L149 PolarHBondContact O-N 3.13Å; L149-L152 PolarHBondContact O-N 3.17Å; L149-A153 PolarHBondContact O-N 3.39Å
150	T	95.3	Very high	95	Very high	0 Å²	0	43 Å²	43	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-54.7	-47.1	-177.4	-76.7	0	0	0	0	113	F146 T147 L152 A153 A154 L161 R165 E168 F227	F146-T150 PolarHBondContact O-N 3.31Å; F146-T150 VanDerWaalsContact O-N 3.12Å; T147-T150 VanDerWaalsContact O-CB 3.24Å; T147-T150 WeakPolarHBondContact O-CB 3.34Å; T147-T150 PolarHBondContact O-N 2.9Å; T147-T150 PolarHBondContact O-OG1 2.98Å; T150-L152 PolarHBondContact O-N 2.99Å; T150-A153 PolarHBondContact O-N 2.86Å; T150-A154 PolarHBondContact O-N 2.88Å; T150-L161 HydrophobicContact CG2-CD1 3.72Å; T150-R165 PolarHBondContact OG1-NH2 3.15Å; T150-E168 PolarHBondContact OG1-OE1 3.49Å; T150-F227 HydrophobicContact CG2-CD1 3.82Å; T150-F227 HydrophobicContact CG2-CD2 3.73Å; T150-F227 HydrophobicContact CG2-CE1 3.78Å; T150-F227 HydrophobicContact CG2-CE2 3.63Å; T150-F227 HydrophobicContact CG2-CG 3.81Å; T150-F227 HydrophobicContact CG2-CZ 3.67Å
151	P	94.4	Very high	94.9	Very high	2 Å²	2	43 Å²	43	1%	0.013	24%	0.236	C	C	.	.	H	α-helix	trans	-60.6	-44.2	179.3	-25.2	35.5	0	0	0	113.4	A153 A154 D155 W223 P224 F227 Y228	P151-A153 VanDerWaalsContact C-N 3.3Å; P151-A153 PolarHBondContact O-N 2.97Å; P151-A154 WeakPolarHBondContact O-CB 3.48Å; P151-A154 PolarHBondContact O-N 3.11Å; P151-D155 PolarHBondContact O-N 3.38Å; P151-D155 VanDerWaalsContact O-N 3.1Å; P151-W223 HydrophobicContact CB-CH2 4.06Å; P151-W223 HydrophobicContact CB-CZ3 3.87Å; P151-W223 HydrophobicContact CG-CZ3 4.16Å; P151-P224 HydrophobicContact CB-CB 4.07Å; P151-P224 HydrophobicContact CG-CB 4.11Å; P151-F227 HydrophobicContact CG-CB 3.95Å; P151-F227 HydrophobicContact CG-CD2 3.97Å; P151-F227 HydrophobicContact CG-CG 4.35Å; P151-Y228 HydrophobicContact CB-CE1 4.46Å; P151-Y228 HydrophobicContact CG-CD1 4.47Å; P151-Y228 HydrophobicContact CG-CE1 3.83Å; P151-Y228 HydrophobicContact CG-CE2 4.39Å
152	L	94	Very high	94.7	Very high	97 Å²	97	43.9 Å²	43.9	51%	0.508	24%	0.24	S	C	.	.	H	α-helix	trans	-63	-39.6	176.8	178.1	65.3	0	0	0	111.3	L149 T150 A154 D155 L156	L149-L152 PolarHBondContact O-N 3.17Å; T150-L152 PolarHBondContact O-N 2.99Å; L152-A154 VanDerWaalsContact C-N 3.33Å; L152-D155 PolarHBondContact O-N 3.02Å; L152-L156 HydrophobicContact CG-CD1 4.37Å; L152-L156 VanDerWaalsContact O-CG 3.31Å; L152-L156 WeakPolarHBondContact O-CG 3.4Å; L152-L156 PolarHBondContact O-N 3.03Å
153	A	94.3	Very high	94.7	Very high	6 Å²	6	47.1 Å²	47.1	5%	0.05	26%	0.256	C	S	.	.	H	α-helix	trans	-66.6	-35	176.8	0	0	0	0	0	112.5	L149 T150 P151 L156 G157 V164	L149-A153 PolarHBondContact O-N 3.39Å; T150-A153 PolarHBondContact O-N 2.86Å; P151-A153 VanDerWaalsContact C-N 3.3Å; P151-A153 PolarHBondContact O-N 2.97Å; A153-L156 PolarHBondContact O-N 3.4Å; A153-G157 PolarHBondContact O-N 3.22Å; A153-G157 VanDerWaalsContact O-N 3.17Å; A153-G157 VanDerWaalsContact O-O 3.06Å; A153-V164 HydrophobicContact CB-CB 4.24Å; A153-V164 HydrophobicContact CB-CG2 3.74Å
154	A	92.6	Very high	94.7	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-65	-42.7	174.9	0	0	0	0	0	111.6	M64 Y98 W100 T150 P151 L152 L156 G157 L161 W223	M64-A154 HydrophobicContact CE-CB 3.72Å; Y98-A154 VanDerWaalsContact CE1-O 3.28Å; Y98-A154 WeakPolarHBondContact CE1-O 3.3Å; Y98-A154 HydrophobicContact CE2-CB 4.04Å; Y98-A154 VanDerWaalsContact OH-C 3.22Å; Y98-A154 WeakPolarHBondContact OH-CB 3.1Å; W100-A154 HydrophobicContact CH2-CB 4.25Å; T150-A154 PolarHBondContact O-N 2.88Å; P151-A154 WeakPolarHBondContact O-CB 3.48Å; P151-A154 PolarHBondContact O-N 3.11Å; L152-A154 VanDerWaalsContact C-N 3.33Å; A154-L156 VanDerWaalsContact C-N 3.29Å; A154-L156 PolarHBondContact O-N 2.99Å; A154-G157 PolarHBondContact O-N 3.44Å; A154-G157 VanDerWaalsContact O-N 3.14Å; A154-L161 HydrophobicContact CB-CD2 4.3Å; A154-W223 HydrophobicContact CB-CH2 3.81Å; A154-W223 HydrophobicContact CB-CZ3 4.38Å
155	D	90.9	Very high	94.5	Very high	109 Å²	109	48.1 Å²	48.1	58%	0.583	26%	0.262	S	S	*	.	H	α-helix	trans	-63.1	-35.1	177.6	-70	-31.6	0	0	0	112	Y98 P151 L152 G157	Y98-D155 WeakPolarHBondContact OH-CA 3.29Å; Y98-D155 PolarHBondContact OH-N 3.31Å; Y98-D155 VanDerWaalsContact OH-N 3.17Å; Y98-D155 PolarHBondContact OH-OD1 2.96Å; P151-D155 PolarHBondContact O-N 3.38Å; P151-D155 VanDerWaalsContact O-N 3.1Å; L152-D155 PolarHBondContact O-N 3.02Å; D155-G157 VanDerWaalsContact C-N 3.35Å
156	L	92.6	Very high	94.4	Very high	106 Å²	106	45.5 Å²	45.5	56%	0.555	25%	0.252	S	S	*	.	H	α-helix	trans	-74.8	-23.3	177.2	-67.7	171.6	0	0	0	113.2	L152 A153 A154 Y160	L152-L156 HydrophobicContact CG-CD1 4.37Å; L152-L156 VanDerWaalsContact O-CG 3.31Å; L152-L156 WeakPolarHBondContact O-CG 3.4Å; L152-L156 PolarHBondContact O-N 3.03Å; A153-L156 PolarHBondContact O-N 3.4Å; A154-L156 VanDerWaalsContact C-N 3.29Å; A154-L156 PolarHBondContact O-N 2.99Å; L156-Y160 HydrophobicContact CB-CD2 3.65Å; L156-Y160 HydrophobicContact CB-CE2 4.16Å; L156-Y160 HydrophobicContact CB-CG 3.92Å; L156-Y160 WeakPolarHBondContact O-CD2 3.03Å
157	G	91.8	Very high	94.4	Very high	23 Å²	23	45.9 Å²	45.9	24%	0.237	26%	0.257	C	S	.	.			trans	129	164.5	173.9	0	0	0	0	0	114.8	A153 A154 D155 S159 Y160 L161	A153-G157 PolarHBondContact O-N 3.22Å; A153-G157 VanDerWaalsContact O-N 3.17Å; A153-G157 VanDerWaalsContact O-O 3.06Å; A154-G157 PolarHBondContact O-N 3.44Å; A154-G157 VanDerWaalsContact O-N 3.14Å; D155-G157 VanDerWaalsContact C-N 3.35Å; G157-S159 VanDerWaalsContact C-N 3.26Å; G157-S159 PolarHBondContact O-N 3.15Å; G157-S159 VanDerWaalsContact O-N 3.14Å; G157-Y160 PolarHBondContact O-N 3.11Å; G157-L161 PolarHBondContact O-N 3.45Å
158	A	90.3	Very high	94.4	Very high	22 Å²	22	46 Å²	46	18%	0.182	26%	0.257	C	S	.	.	H	α-helix	trans	-56.4	-35.1	-173.2	0	0	0	0	0	114.1	T104 I108 L161 I162	T104-A158 HydrophobicContact CG2-CB 3.67Å; I108-A158 HydrophobicContact CD1-CB 4.22Å; A158-L161 PolarHBondContact O-N 3.48Å; A158-I162 VanDerWaalsContact O-CG1 3.27Å; A158-I162 WeakPolarHBondContact O-CG1 3.08Å; A158-I162 PolarHBondContact O-N 3.21Å
159	S	92.9	Very high	94.3	Very high	78 Å²	78	43.6 Å²	43.6	55%	0.545	24%	0.244	S	C	.	.	H	α-helix	trans	-64.3	-40.2	178.3	52.2	0	0	0	0	112.7	G157 I162 V163	G157-S159 VanDerWaalsContact C-N 3.26Å; G157-S159 PolarHBondContact O-N 3.15Å; G157-S159 VanDerWaalsContact O-N 3.14Å; S159-I162 PolarHBondContact O-N 3.38Å; S159-V163 WeakPolarHBondContact O-CG2 3.37Å; S159-V163 PolarHBondContact O-N 3.22Å; S159-V163 VanDerWaalsContact O-N 3.15Å
160	Y	95.1	Very high	94.2	Very high	130 Å²	130	42.1 Å²	42.1	51%	0.51	24%	0.239	S	C	.	.	H	α-helix	trans	-68.5	-41	177.3	-66	-83.1	0	0	0	110.7	L156 G157 I162 V163 V164	L156-Y160 HydrophobicContact CB-CD2 3.65Å; L156-Y160 HydrophobicContact CB-CE2 4.16Å; L156-Y160 HydrophobicContact CB-CG 3.92Å; L156-Y160 WeakPolarHBondContact O-CD2 3.03Å; G157-Y160 PolarHBondContact O-N 3.11Å; Y160-I162 VanDerWaalsContact C-N 3.34Å; Y160-I162 PolarHBondContact O-N 3.28Å; Y160-V163 PolarHBondContact O-N 2.95Å; Y160-V164 WeakPolarHBondContact O-CG2 3.25Å; Y160-V164 PolarHBondContact O-N 2.87Å
161	L	94.4	Very high	94.2	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-60.5	-42.5	174.9	-177.4	56.7	0	0	0	112	M64 W100 I108 T150 A154 G157 A158 V163 V164 R165	M64-L161 HydrophobicContact CE-CD2 4.24Å; W100-L161 HydrophobicContact CH2-CD2 3.55Å; W100-L161 HydrophobicContact CZ2-CD2 4.31Å; W100-L161 HydrophobicContact CZ3-CD2 4.01Å; I108-L161 HydrophobicContact CD1-CD2 4.13Å; I108-L161 HydrophobicContact CG1-CD2 4.45Å; I108-L161 HydrophobicContact CG2-CD2 3.75Å; I108-L161 HydrophobicContact CG2-CG 3.86Å; T150-L161 HydrophobicContact CG2-CD1 3.72Å; A154-L161 HydrophobicContact CB-CD2 4.3Å; G157-L161 PolarHBondContact O-N 3.45Å; A158-L161 PolarHBondContact O-N 3.48Å; L161-V163 VanDerWaalsContact C-N 3.34Å; L161-V163 PolarHBondContact O-N 3.24Å; L161-V164 PolarHBondContact O-N 3.09Å; L161-R165 HydrophobicContact CD1-CG 4.19Å; L161-R165 HydrophobicContact CG-CG 4.46Å; L161-R165 VanDerWaalsContact O-CB 3.3Å; L161-R165 WeakPolarHBondContact O-CB 3.25Å; L161-R165 WeakPolarHBondContact O-CG 3.02Å; L161-R165 PolarHBondContact O-N 3.01Å
162	I	94.3	Very high	94.2	Very high	53 Å²	53	42.7 Å²	42.7	27%	0.272	24%	0.244	S	C	.	.	H	α-helix	trans	-58.5	-44	174.2	-74.3	164.6	0	0	0	111.6	W107 I108 S111 A158 S159 Y160 R165 A166	W107-I162 HydrophobicContact CB-CD1 4.1Å; I108-I162 HydrophobicContact CB-CG1 4.42Å; I108-I162 HydrophobicContact CG1-CD1 4.24Å; I108-I162 HydrophobicContact CG1-CG1 3.77Å; S111-I162 PolarHBondContact OG-O 2.98Å; A158-I162 VanDerWaalsContact O-CG1 3.27Å; A158-I162 WeakPolarHBondContact O-CG1 3.08Å; A158-I162 PolarHBondContact O-N 3.21Å; S159-I162 PolarHBondContact O-N 3.38Å; Y160-I162 VanDerWaalsContact C-N 3.34Å; Y160-I162 PolarHBondContact O-N 3.28Å; I162-R165 PolarHBondContact O-N 3.06Å; I162-A166 WeakPolarHBondContact O-CB 3.43Å; I162-A166 PolarHBondContact O-N 3.24Å
163	V	96.3	Very high	94.1	Very high	85 Å²	85	38 Å²	38	52%	0.515	22%	0.22	S	C	.	.	H	α-helix	trans	-66.1	-46.9	179.2	172.5	0	0	0	0	111.1	S159 Y160 L161 R165 A166 L167	S159-V163 WeakPolarHBondContact O-CG2 3.37Å; S159-V163 PolarHBondContact O-N 3.22Å; S159-V163 VanDerWaalsContact O-N 3.15Å; Y160-V163 PolarHBondContact O-N 2.95Å; L161-V163 VanDerWaalsContact C-N 3.34Å; L161-V163 PolarHBondContact O-N 3.24Å; V163-R165 VanDerWaalsContact C-N 3.29Å; V163-R165 PolarHBondContact O-N 2.95Å; V163-A166 PolarHBondContact O-N 3.43Å; V163-L167 HydrophobicContact CG1-CD1 4.22Å; V163-L167 WeakPolarHBondContact O-CG 3.4Å; V163-L167 PolarHBondContact O-N 3.31Å
164	V	96.5	Very high	94.1	Very high	19 Å²	19	38.4 Å²	38.4	12%	0.115	22%	0.222	C	C	.	.	H	α-helix	trans	-59.6	-43	177.6	170	0	0	0	0	110.8	F146 A153 Y160 L161 A166 L167 E168	F146-V164 HydrophobicContact CB-CG1 4.03Å; F146-V164 VanDerWaalsContact O-CG1 3.23Å; F146-V164 WeakPolarHBondContact O-CG1 3.28Å; A153-V164 HydrophobicContact CB-CB 4.24Å; A153-V164 HydrophobicContact CB-CG2 3.74Å; Y160-V164 WeakPolarHBondContact O-CG2 3.25Å; Y160-V164 PolarHBondContact O-N 2.87Å; L161-V164 PolarHBondContact O-N 3.09Å; V164-A166 PolarHBondContact O-N 2.65Å; V164-L167 WeakPolarHBondContact O-CB 3.39Å; V164-L167 PolarHBondContact O-N 3.11Å; V164-L167 VanDerWaalsContact O-N 3.15Å; V164-E168 WeakPolarHBondContact O-CG 3.41Å; V164-E168 PolarHBondContact O-N 3.17Å
165	R	94.4	Very high	94.1	Very high	5 Å²	5	38.4 Å²	38.4	2%	0.019	22%	0.222	C	C	.	.	H	α-helix	trans	-63.3	-40.6	176.3	-74.7	-75.7	147.7	169.3	-2.9	113.1	L57 S111 F112 T150 L161 I162 V163 L167 E168 G169	L57-R165 HydrophobicContact CD2-CG 4.37Å; L57-R165 VanDerWaalsContact CD2-CZ 3.46Å; S111-R165 WeakPolarHBondContact OG-CB 3.41Å; F112-R165 WeakPolarHBondContact CA-O 3.36Å; T150-R165 PolarHBondContact OG1-NH2 3.15Å; L161-R165 HydrophobicContact CD1-CG 4.19Å; L161-R165 HydrophobicContact CG-CG 4.46Å; L161-R165 VanDerWaalsContact O-CB 3.3Å; L161-R165 WeakPolarHBondContact O-CB 3.25Å; L161-R165 WeakPolarHBondContact O-CG 3.02Å; L161-R165 PolarHBondContact O-N 3.01Å; I162-R165 PolarHBondContact O-N 3.06Å; V163-R165 VanDerWaalsContact C-N 3.29Å; V163-R165 PolarHBondContact O-N 2.95Å; R165-L167 VanDerWaalsContact C-N 3.31Å; R165-L167 PolarHBondContact O-N 3.12Å; R165-E168 WeakPolarHBondContact CD-OE2 3.39Å; R165-E168 IonicContact CZ-OE1 3.98Å; R165-E168 IonicContact CZ-OE2 3.34Å; R165-E168 IonicContact NE-OE1 3.24Å; R165-E168 IonicContact NE-OE2 3.83Å; R165-E168 PolarHBondContact NE-OE2 2.98Å; R165-E168 IonicContact NH1-OE2 3.94Å; R165-E168 PolarHBondContact NH1-OE2 3.33Å; R165-E168 IonicContact NH2-OE1 3.01Å; R165-E168 IonicContact NH2-OE2 3.05Å; R165-E168 WeakPolarHBondContact O-CB 3.41Å; R165-E168 PolarHBondContact O-N 3.33Å; R165-G169 PolarHBondContact O-N 2.95Å; R165-G169 VanDerWaalsContact O-N 3.09Å
166	A	95.6	Very high	94.1	Very high	29 Å²	29	34.3 Å²	34.3	24%	0.24	20%	0.199	C	C	.	.	H	α-helix	trans	-62.2	-40.6	173.1	0	0	0	0	0	111.3	G115 I162 V163 V164 G169 V170	G115-A166 WeakPolarHBondContact CA-O 2.93Å; I162-A166 WeakPolarHBondContact O-CB 3.43Å; I162-A166 PolarHBondContact O-N 3.24Å; V163-A166 PolarHBondContact O-N 3.43Å; V164-A166 PolarHBondContact O-N 2.65Å; A166-G169 PolarHBondContact O-N 3.1Å; A166-V170 WeakPolarHBondContact O-CG2 3.37Å; A166-V170 PolarHBondContact O-N 3.06Å
167	L	96.6	Very high	94	Very high	68 Å²	68	29.3 Å²	29.3	36%	0.356	17%	0.173	S	C	.	.	H	α-helix	trans	-67	-37.6	176.9	-67.1	172.9	0	0	0	113	F146 V163 V164 R165 G169 V170 G171	F146-L167 HydrophobicContact CD1-CB 4.26Å; F146-L167 HydrophobicContact CD1-CD1 4.25Å; F146-L167 HydrophobicContact CD2-CB 3.74Å; F146-L167 HydrophobicContact CE1-CB 4.22Å; F146-L167 HydrophobicContact CE1-CD1 3.75Å; F146-L167 HydrophobicContact CE2-CB 3.7Å; F146-L167 HydrophobicContact CG-CB 4.05Å; F146-L167 HydrophobicContact CZ-CB 3.96Å; F146-L167 HydrophobicContact CZ-CD1 3.91Å; F146-L167 HydrophobicContact CZ-CG 4.4Å; V163-L167 HydrophobicContact CG1-CD1 4.22Å; V163-L167 WeakPolarHBondContact O-CG 3.4Å; V163-L167 PolarHBondContact O-N 3.31Å; V164-L167 WeakPolarHBondContact O-CB 3.39Å; V164-L167 PolarHBondContact O-N 3.11Å; V164-L167 VanDerWaalsContact O-N 3.15Å; R165-L167 VanDerWaalsContact C-N 3.31Å; R165-L167 PolarHBondContact O-N 3.12Å; L167-G169 VanDerWaalsContact C-N 3.29Å; L167-G169 PolarHBondContact O-N 3.22Å; L167-V170 PolarHBondContact O-N 3.4Å; L167-G171 PolarHBondContact O-N 3.4Å; L167-G171 VanDerWaalsContact O-N 3.11Å
168	E	96.2	Very high	94	Very high	2 Å²	2	28.2 Å²	28.2	1%	0.009	16%	0.161	C	C	.	.	H	α-helix	trans	-55.5	-46.7	169.4	-72.7	177.1	164.6	0	0	111	F112 T143 F146 T147 T150 V164 R165 G171 E172	F112-E168 HydrophobicContact CD2-CB 4.16Å; F112-E168 HydrophobicContact CE2-CB 4.36Å; T143-E168 HydrophobicContact CG2-CB 4.1Å; T143-E168 HydrophobicContact CG2-CG 4.36Å; T143-E168 PolarHBondContact OG1-O 2.95Å; F146-E168 HydrophobicContact CB-CG 3.55Å; T147-E168 WeakPolarHBondContact CA-OE1 3.46Å; T147-E168 WeakPolarHBondContact CB-OE1 3.3Å; T147-E168 PolarHBondContact N-OE1 3.06Å; T147-E168 VanDerWaalsContact N-OE1 3.16Å; T147-E168 PolarHBondContact OG1-OE1 3.47Å; T150-E168 PolarHBondContact OG1-OE1 3.49Å; V164-E168 WeakPolarHBondContact O-CG 3.41Å; V164-E168 PolarHBondContact O-N 3.17Å; R165-E168 WeakPolarHBondContact CD-OE2 3.39Å; R165-E168 IonicContact CZ-OE1 3.98Å; R165-E168 IonicContact CZ-OE2 3.34Å; R165-E168 IonicContact NE-OE1 3.24Å; R165-E168 IonicContact NE-OE2 3.83Å; R165-E168 PolarHBondContact NE-OE2 2.98Å; R165-E168 IonicContact NH1-OE2 3.94Å; R165-E168 PolarHBondContact NH1-OE2 3.33Å; R165-E168 IonicContact NH2-OE1 3.01Å; R165-E168 IonicContact NH2-OE2 3.05Å; R165-E168 WeakPolarHBondContact O-CB 3.41Å; R165-E168 PolarHBondContact O-N 3.33Å; E168-G171 PolarHBondContact O-N 2.8Å; E168-E172 WeakPolarHBondContact O-CB 3.41Å; E168-E172 PolarHBondContact O-N 3.49Å
169	G	95	Very high	94.1	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-60	-44.3	176.5	0	0	0	0	0	113.1	F112 Y116 R165 A166 L167 G171 E172 G173	F112-G169 WeakPolarHBondContact O-CA 3.48Å; Y116-G169 VanDerWaalsContact CA-O 3.25Å; Y116-G169 WeakPolarHBondContact CA-O 3.15Å; R165-G169 PolarHBondContact O-N 2.95Å; R165-G169 VanDerWaalsContact O-N 3.09Å; A166-G169 PolarHBondContact O-N 3.1Å; L167-G169 VanDerWaalsContact C-N 3.29Å; L167-G169 PolarHBondContact O-N 3.22Å; G169-G171 VanDerWaalsContact C-N 3.33Å; G169-G171 PolarHBondContact O-N 3.23Å; G169-E172 PolarHBondContact O-N 2.6Å; G169-G173 PolarHBondContact O-N 3.29Å
170	V	95.8	Very high	93.8	Very high	51 Å²	51	24 Å²	24	31%	0.309	13%	0.129	S	C	.	.	H	α-helix	trans	-56.7	-47.5	176.3	168.2	0	0	0	0	110.9	T119 A166 L167	T119-V170 HydrophobicContact CG2-CB 4.24Å; T119-V170 HydrophobicContact CG2-CG1 3.66Å; T119-V170 WeakPolarHBondContact CG2-O 3.4Å; T119-V170 PolarHBondContact OG1-O 2.92Å; A166-V170 WeakPolarHBondContact O-CG2 3.37Å; A166-V170 PolarHBondContact O-N 3.06Å; L167-V170 PolarHBondContact O-N 3.4Å
171	G	94.4	Very high	93.4	Very high	12 Å²	12	19.3 Å²	19.3	12%	0.124	11%	0.114	C	C	.	.	H	α-helix	trans	-64.8	-40.3	177.8	0	0	0	0	0	112.8	G139 L167 E168 G169 V174	G139-G171 CarbonylContact C-O 3.6Å; G139-G171 WeakPolarHBondContact CA-O 3.38Å; G139-G171 CarbonylContact O-C 3.5Å; L167-G171 PolarHBondContact O-N 3.4Å; L167-G171 VanDerWaalsContact O-N 3.11Å; E168-G171 PolarHBondContact O-N 2.8Å; G169-G171 VanDerWaalsContact C-N 3.33Å; G169-G171 PolarHBondContact O-N 3.23Å; G171-V174 WeakPolarHBondContact O-CG2 3.29Å
172	E	94.1	Very high	93.2	Very high	1 Å²	1	19.5 Å²	19.5	1%	0.005	12%	0.115	C	C	.	.	H	α-helix	trans	-78.3	-26.3	-176.1	-154.3	177.9	134.8	0	0	112.7	V50 R54 F112 Y116 T143 E168 G169 V174 T175	V50-E172 HydrophobicContact CG1-CG 3.6Å; V50-E172 WeakPolarHBondContact CG1-OE1 3.33Å; R54-E172 IonicContact CZ-OE1 3.11Å; R54-E172 IonicContact NE-OE1 2.79Å; R54-E172 PolarHBondContact NE-OE1 2.73Å; R54-E172 IonicContact NH2-OE1 2.66Å; R54-E172 PolarHBondContact NH2-OE1 3.23Å; F112-E172 HydrophobicContact CE2-CB 4.16Å; F112-E172 WeakPolarHBondContact CE2-OE2 3.49Å; F112-E172 HydrophobicContact CZ-CB 4Å; F112-E172 HydrophobicContact CZ-CG 4.28Å; F112-E172 WeakPolarHBondContact CZ-OE2 3.45Å; Y116-E172 HydrophobicContact CD2-CB 4.16Å; Y116-E172 HydrophobicContact CE2-CB 4.23Å; Y116-E172 HydrophobicContact CE2-CG 4.32Å; T143-E172 HydrophobicContact CG2-CB 4.43Å; T143-E172 PolarHBondContact OG1-N 3.28Å; T143-E172 VanDerWaalsContact OG1-N 3.17Å; E168-E172 WeakPolarHBondContact O-CB 3.41Å; E168-E172 PolarHBondContact O-N 3.49Å; G169-E172 PolarHBondContact O-N 2.6Å; E172-V174 PolarHBondContact O-N 3.03Å; E172-T175 HydrophobicContact CG-CG2 4.39Å; E172-T175 WeakPolarHBondContact O-CB 3.06Å; E172-T175 VanDerWaalsContact O-CG2 3.29Å; E172-T175 WeakPolarHBondContact O-CG2 3.42Å; E172-T175 PolarHBondContact O-N 2.76Å; E172-T175 VanDerWaalsContact O-N 3.11Å; E172-T175 PolarHBondContact O-OG1 3.24Å
173	G	92.6	Very high	93	Very high	0 Å²	0	17 Å²	17	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-63.3	-23	-176	0	0	0	0	0	114.9	Y116 T119 Q120 G169 P177	Y116-G173 VanDerWaalsContact CE2-CA 3.43Å; T119-G173 VanDerWaalsContact OG1-CA 3.25Å; T119-G173 WeakPolarHBondContact OG1-CA 3.26Å; Q120-G173 PolarHBondContact NE2-O 3.38Å; Q120-G173 PolarHBondContact OE1-O 3.29Å; G169-G173 PolarHBondContact O-N 3.29Å; G173-P177 WeakPolarHBondContact O-CD 3.24Å
174	V	93.8	Very high	92.4	Very high	14 Å²	14	13.6 Å²	13.6	9%	0.085	8%	0.083	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.9	-12.2	177.6	-57.2	0	0	0	0	114	L135 G171 E172 A178	L135-V174 HydrophobicContact CD1-CB 4.21Å; L135-V174 HydrophobicContact CD1-CG1 4.23Å; L135-V174 HydrophobicContact CD1-CG2 4.19Å; L135-V174 HydrophobicContact CD2-CB 4.18Å; L135-V174 HydrophobicContact CG-CB 3.91Å; L135-V174 HydrophobicContact CG-CG1 4.43Å; L135-V174 HydrophobicContact CG-CG2 3.99Å; L135-V174 WeakPolarHBondContact O-CG2 3.36Å; G171-V174 WeakPolarHBondContact O-CG2 3.29Å; E172-V174 PolarHBondContact O-N 3.03Å; V174-A178 WeakPolarHBondContact O-CB 3.38Å; V174-A178 PolarHBondContact O-N 3.45Å
175	T	93.6	Very high	91.8	Very high	0 Å²	0	14 Å²	14	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-64.3	-51.8	-170.1	56.6	0	0	0	0	113.4	V50 V140 E172 A178 M179	V50-T175 HydrophobicContact CG2-CG2 4.13Å; V140-T175 HydrophobicContact CG2-CG2 3.81Å; E172-T175 HydrophobicContact CG-CG2 4.39Å; E172-T175 WeakPolarHBondContact O-CB 3.06Å; E172-T175 VanDerWaalsContact O-CG2 3.29Å; E172-T175 WeakPolarHBondContact O-CG2 3.42Å; E172-T175 PolarHBondContact O-N 2.76Å; E172-T175 VanDerWaalsContact O-N 3.11Å; E172-T175 PolarHBondContact O-OG1 3.24Å; T175-A178 PolarHBondContact O-N 2.72Å; T175-M179 PolarHBondContact O-N 3.43Å
176	F	90.9	Very high	91.6	Very high	23 Å²	23	13.9 Å²	13.9	10%	0.101	9%	0.088	C	C	.	.	H	α-helix	trans	-63.7	-51.4	-179.9	-81.1	-90.2	0	0	0	112.8	F47 Y51 Y116 A178 M179 Y180 Y200 L424	F47-F176 HydrophobicContact CD1-CE1 4.34Å; F47-F176 HydrophobicContact CD1-CE2 4.33Å; F47-F176 HydrophobicContact CD1-CZ 4.08Å; F47-F176 AromaticContact CE1-CD1 3.93Å; F47-F176 HydrophobicContact CE1-CD1 3.93Å; F47-F176 AromaticContact CE1-CD2 4Å; F47-F176 HydrophobicContact CE1-CD2 4Å; F47-F176 AromaticContact CE1-CE1 3.84Å; F47-F176 HydrophobicContact CE1-CE1 3.84Å; F47-F176 AromaticContact CE1-CE2 3.92Å; F47-F176 HydrophobicContact CE1-CE2 3.92Å; F47-F176 HydrophobicContact CE1-CG 4.02Å; F47-F176 AromaticContact CE1-CZ 3.84Å; F47-F176 HydrophobicContact CE1-CZ 3.84Å; F47-F176 HydrophobicContact CZ-CD1 4.36Å; Y51-F176 AromaticContact CE2-CE2 3.87Å; Y51-F176 HydrophobicContact CE2-CE2 3.87Å; Y51-F176 AromaticContact CE2-CZ 3.71Å; Y51-F176 HydrophobicContact CE2-CZ 3.71Å; Y116-F176 WeakPolarHBondContact OH-CD2 3.43Å; Y116-F176 WeakPolarHBondContact OH-CE2 3.26Å; F176-A178 VanDerWaalsContact C-N 3.32Å; F176-A178 PolarHBondContact O-N 3.23Å; F176-M179 PolarHBondContact O-N 3.16Å; F176-Y180 PolarHBondContact O-N 3.09Å; F176-Y200 HydrophobicContact CD1-CD1 4.13Å; F176-Y200 AromaticContact CD1-CE1 3.48Å; F176-Y200 HydrophobicContact CD1-CE1 3.48Å; F176-Y200 VanDerWaalsContact CD1-CE1 3.48Å; F176-Y200 AromaticContact CE1-CD1 3.65Å; F176-Y200 HydrophobicContact CE1-CD1 3.65Å; F176-Y200 AromaticContact CE1-CE1 3.49Å; F176-Y200 HydrophobicContact CE1-CE1 3.49Å; F176-Y200 VanDerWaalsContact CE1-CE1 3.49Å; F176-L424 HydrophobicContact CB-CD2 3.77Å
177	P	89.3	Confident	91.2	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-60	-39.4	176.7	-23.4	32.4	0	0	0	113.4	Q120 G173 Y180 T181	Q120-P177 WeakPolarHBondContact O-CG 3.29Å; G173-P177 WeakPolarHBondContact O-CD 3.24Å; P177-Y180 PolarHBondContact O-N 3.27Å; P177-T181 PolarHBondContact O-N 2.99Å; P177-T181 VanDerWaalsContact O-N 3.09Å; P177-T181 PolarHBondContact O-OG1 3.44Å
178	A	92.1	Very high	90.6	Very high	0 Å²	0	9.3 Å²	9.3	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-62.1	-45.2	176.2	0	0	0	0	0	111.4	A127 A132 L135 M136 V174 T175 F176 Y180 T181 M182	A127-A178 HydrophobicContact CB-CB 4.28Å; A132-A178 WeakPolarHBondContact CB-O 3.44Å; L135-A178 HydrophobicContact CB-CB 4.48Å; L135-A178 HydrophobicContact CD2-CB 4.36Å; M136-A178 HydrophobicContact CB-CB 3.94Å; V174-A178 WeakPolarHBondContact O-CB 3.38Å; V174-A178 PolarHBondContact O-N 3.45Å; T175-A178 PolarHBondContact O-N 2.72Å; F176-A178 VanDerWaalsContact C-N 3.32Å; F176-A178 PolarHBondContact O-N 3.23Å; A178-Y180 PolarHBondContact O-N 2.93Å; A178-T181 WeakPolarHBondContact O-CB 3.49Å; A178-T181 PolarHBondContact O-N 3.41Å; A178-M182 PolarHBondContact O-N 3.36Å
179	M	91.8	Very high	89.6	Confident	1 Å²	1	11.7 Å²	11.7	1%	0.005	8%	0.075	C	C	.	.	H	α-helix	trans	-66	-38.4	179.3	-164.4	70.5	-142.3	0	0	113.1	L39 S43 F47 M136 T175 F176 T181 M182 W183 W241	L39-M179 HydrophobicContact CD1-CE 4.45Å; L39-M179 HydrophobicContact CG-CE 4.35Å; S43-M179 WeakPolarHBondContact OG-CE 3.5Å; S43-M179 PolarHBondContact OG-SD 3.02Å; S43-M179 VanDerWaalsContact OG-SD 3.39Å; F47-M179 HydrophobicContact CE2-CB 3.99Å; F47-M179 HydrophobicContact CE2-CG 3.79Å; F47-M179 HydrophobicContact CE2-SD 4.49Å; F47-M179 HydrophobicContact CZ-CB 3.83Å; F47-M179 HydrophobicContact CZ-CG 4.16Å; M136-M179 HydrophobicContact SD-CB 4.48Å; M136-M179 HydrophobicContact SD-SD 3.95Å; T175-M179 PolarHBondContact O-N 3.43Å; F176-M179 PolarHBondContact O-N 3.16Å; M179-T181 VanDerWaalsContact C-N 3.31Å; M179-T181 PolarHBondContact O-N 2.69Å; M179-M182 HydrophobicContact CE-CB 3.95Å; M179-M182 HydrophobicContact CE-CG 3.85Å; M179-M182 WeakPolarHBondContact O-CB 3.13Å; M179-M182 PolarHBondContact O-N 2.85Å; M179-M182 HydrophobicContact SD-CB 4.37Å; M179-W183 HydrophobicContact CE-CD2 4.02Å; M179-W183 HydrophobicContact CE-CG 4.13Å; M179-W183 HydrophobicContact CE-CZ2 3.71Å; M179-W183 PolarHBondContact O-N 3.07Å; M179-W241 HydrophobicContact SD-CH2 4.31Å
180	Y	87.8	Confident	88.5	Confident	10 Å²	10	17.3 Å²	17.3	4%	0.039	11%	0.105	C	C	.	.	H	α-helix	trans	-63.6	-39.1	174.7	-92.9	-108.7	0	0	0	111.8	F176 P177 A178 M182 W183 A184 Y200 N409 H412 L413 A420 L424	F176-Y180 PolarHBondContact O-N 3.09Å; P177-Y180 PolarHBondContact O-N 3.27Å; A178-Y180 PolarHBondContact O-N 2.93Å; Y180-M182 VanDerWaalsContact C-N 3.34Å; Y180-W183 PolarHBondContact O-N 3.3Å; Y180-A184 PolarHBondContact O-N 3.19Å; Y180-Y200 HydrophobicContact CD2-CE2 4.34Å; Y180-Y200 AromaticContact CD2-CZ 3.86Å; Y180-Y200 WeakPolarHBondContact CD2-OH 3.32Å; Y180-Y200 HydrophobicContact CE2-CE1 4.41Å; Y180-Y200 AromaticContact CE2-CE2 3.69Å; Y180-Y200 HydrophobicContact CE2-CE2 3.69Å; Y180-Y200 AromaticContact CE2-CZ 3.46Å; Y180-Y200 VanDerWaalsContact CE2-CZ 3.46Å; Y180-Y200 WeakPolarHBondContact CE2-OH 3.37Å; Y180-N409 PolarHBondContact OH-O 3.02Å; Y180-N409 VanDerWaalsContact OH-O 3.13Å; Y180-H412 HydrophobicContact CE1-CB 4.26Å; Y180-L413 HydrophobicContact CD1-CD1 3.89Å; Y180-L413 HydrophobicContact CD1-CD2 4.44Å; Y180-L413 HydrophobicContact CD1-CG 4.08Å; Y180-L413 HydrophobicContact CE1-CD1 3.68Å; Y180-L413 HydrophobicContact CE1-CG 4.09Å; Y180-A420 HydrophobicContact CD1-CB 4.29Å; Y180-L424 HydrophobicContact CD1-CB 4.3Å; Y180-L424 HydrophobicContact CD1-CD2 4.38Å; Y180-L424 HydrophobicContact CD2-CB 4.44Å; Y180-L424 HydrophobicContact CD2-CD1 4.25Å; Y180-L424 HydrophobicContact CD2-CD2 3.12Å; Y180-L424 HydrophobicContact CD2-CG 4.09Å; Y180-L424 HydrophobicContact CE1-CD1 4.15Å; Y180-L424 HydrophobicContact CE2-CD1 3.73Å; Y180-L424 HydrophobicContact CE2-CD2 3.38Å; Y180-L424 HydrophobicContact CE2-CG 4.07Å; Y180-L424 HydrophobicContact CG-CB 4.22Å; Y180-L424 HydrophobicContact CG-CD2 3.66Å; Y180-L424 HydrophobicContact CG-CG 4.37Å
181	T	86.5	Confident	87.6	Confident	32 Å²	32	15.9 Å²	15.9	20%	0.196	10%	0.095	C	C	.	.	H	α-helix	trans	-62.7	-41.3	172.7	-58.7	0	0	0	0	111.4	A127 A132 P177 A178 M179 A184 A185	A127-T181 HydrophobicContact CB-CG2 4.07Å; A132-T181 HydrophobicContact CB-CG2 4.25Å; P177-T181 PolarHBondContact O-N 2.99Å; P177-T181 VanDerWaalsContact O-N 3.09Å; P177-T181 PolarHBondContact O-OG1 3.44Å; A178-T181 WeakPolarHBondContact O-CB 3.49Å; A178-T181 PolarHBondContact O-N 3.41Å; M179-T181 VanDerWaalsContact C-N 3.31Å; M179-T181 PolarHBondContact O-N 2.69Å; T181-A184 WeakPolarHBondContact O-CB 3.41Å; T181-A184 PolarHBondContact O-N 3.46Å; T181-A185 PolarHBondContact O-N 3.45Å
182	M	89.8	Confident	86.8	Confident	4 Å²	4	15.8 Å²	15.8	2%	0.02	9%	0.091	C	C	.	.	H	α-helix	trans	-60.8	-46.3	174.6	-171.4	67.4	74.3	0	0	111.6	L39 A132 K133 A178 M179 Y180 A184 A185 W186 V245	L39-M182 HydrophobicContact CD2-CG 3.99Å; A132-M182 HydrophobicContact CB-CB 4.15Å; A132-M182 HydrophobicContact CB-CE 3.83Å; K133-M182 HydrophobicContact CB-CE 3.79Å; K133-M182 VanDerWaalsContact N-CE 3.3Å; A178-M182 PolarHBondContact O-N 3.36Å; M179-M182 HydrophobicContact CE-CB 3.95Å; M179-M182 HydrophobicContact CE-CG 3.85Å; M179-M182 WeakPolarHBondContact O-CB 3.13Å; M179-M182 PolarHBondContact O-N 2.85Å; M179-M182 HydrophobicContact SD-CB 4.37Å; Y180-M182 VanDerWaalsContact C-N 3.34Å; M182-A184 VanDerWaalsContact C-N 3.3Å; M182-A184 PolarHBondContact O-N 3.01Å; M182-A185 PolarHBondContact O-N 3.3Å; M182-W186 PolarHBondContact O-N 2.96Å; M182-W186 VanDerWaalsContact SD-CD1 3.59Å; M182-V245 HydrophobicContact CE-CG1 4.32Å
183	W	89.3	Confident	85.9	Confident	0 Å²	0	16.1 Å²	16.1	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-67.9	-28.3	179.4	-78.3	124.6	0	0	0	113.6	L39 A40 M179 Y180 A185 W186 A187 L195 L196 S199	L39-W183 HydrophobicContact CB-CH2 4.35Å; L39-W183 HydrophobicContact CD2-CH2 4.12Å; L39-W183 HydrophobicContact CD2-CZ3 4.18Å; L39-W183 HydrophobicContact CG-CH2 4.05Å; L39-W183 HydrophobicContact CG-CZ2 4.36Å; A40-W183 HydrophobicContact CB-CH2 3.76Å; A40-W183 HydrophobicContact CB-CZ2 3.89Å; M179-W183 HydrophobicContact CE-CD2 4.02Å; M179-W183 HydrophobicContact CE-CG 4.13Å; M179-W183 HydrophobicContact CE-CZ2 3.71Å; M179-W183 PolarHBondContact O-N 3.07Å; Y180-W183 PolarHBondContact O-N 3.3Å; W183-A185 PolarHBondContact O-N 2.92Å; W183-W186 HydrophobicContact CE3-CB 4.03Å; W183-W186 HydrophobicContact CZ3-CB 4.13Å; W183-W186 PolarHBondContact O-N 3.43Å; W183-A187 HydrophobicContact CB-CB 4.43Å; W183-A187 HydrophobicContact CD2-CB 4.46Å; W183-A187 HydrophobicContact CE3-CB 3.7Å; W183-A187 HydrophobicContact CZ3-CB 4.44Å; W183-A187 VanDerWaalsContact O-CB 3.26Å; W183-A187 WeakPolarHBondContact O-CB 3.47Å; W183-A187 PolarHBondContact O-N 3.23Å; W183-L195 HydrophobicContact CD2-CB 4.49Å; W183-L195 HydrophobicContact CE3-CB 4.13Å; W183-L195 HydrophobicContact CE3-CD1 4.3Å; W183-L195 HydrophobicContact CH2-CB 3.9Å; W183-L195 HydrophobicContact CH2-CD2 4.17Å; W183-L195 HydrophobicContact CH2-CG 4.4Å; W183-L195 HydrophobicContact CZ2-CB 4.28Å; W183-L195 HydrophobicContact CZ3-CB 3.8Å; W183-L195 HydrophobicContact CZ3-CD1 3.8Å; W183-L195 HydrophobicContact CZ3-CD2 4.26Å; W183-L195 HydrophobicContact CZ3-CG 4.16Å; W183-L196 HydrophobicContact CB-CD2 4.06Å; W183-L196 HydrophobicContact CG-CD2 3.78Å; W183-S199 WeakPolarHBondContact CZ2-OG 3.44Å; W183-S199 PolarHBondContact NE1-OG 3.16Å
184	A	84.4	Confident	85.3	Confident	15 Å²	15	20 Å²	20	12%	0.124	11%	0.107	C	C	.	.	H	α-helix	trans	-61	-31.4	171.1	0	0	0	0	0	112.2	Y180 T181 M182	Y180-A184 PolarHBondContact O-N 3.19Å; T181-A184 WeakPolarHBondContact O-CB 3.41Å; T181-A184 PolarHBondContact O-N 3.46Å; M182-A184 VanDerWaalsContact C-N 3.3Å; M182-A184 PolarHBondContact O-N 3.01Å
185	A	84.9	Confident	85	Confident	26 Å²	26	19.3 Å²	19.3	22%	0.215	10%	0.103	C	C	.	.	H	α-helix	trans	-88.8	-24	177.8	0	0	0	0	0	114.4	T181 M182 W183 L267	T181-A185 PolarHBondContact O-N 3.45Å; M182-A185 PolarHBondContact O-N 3.3Å; W183-A185 PolarHBondContact O-N 2.92Å; A185-L267 WeakPolarHBondContact O-CD1 3.41Å
186	W	89.8	Confident	84.5	Confident	3 Å²	3	19.4 Å²	19.4	1%	0.011	10%	0.104	C	C	.	.	H	α-helix	trans	-110.4	-25.9	-172.1	-82.2	86.5	0	0	0	115.5	R36 L39 M182 W183 P188 F246 D247 P249 H252 I255 I263	R36-W186 HydrophobicContact CB-CE3 4.38Å; L39-W186 HydrophobicContact CD2-CB 3.93Å; L39-W186 HydrophobicContact CD2-CD2 3.63Å; L39-W186 HydrophobicContact CD2-CE3 4.1Å; L39-W186 HydrophobicContact CD2-CG 3.55Å; M182-W186 PolarHBondContact O-N 2.96Å; M182-W186 VanDerWaalsContact SD-CD1 3.59Å; W183-W186 HydrophobicContact CE3-CB 4.03Å; W183-W186 HydrophobicContact CZ3-CB 4.13Å; W183-W186 PolarHBondContact O-N 3.43Å; W186-P188 VanDerWaalsContact O-CD 3.32Å; W186-P188 WeakPolarHBondContact O-CD 3.48Å; W186-F246 WeakPolarHBondContact CZ2-O 3.26Å; W186-F246 PolarHBondContact NE1-O 3.31Å; W186-D247 PolarHBondContact NE1-O 3.34Å; W186-P249 HydrophobicContact CD2-CG 3.98Å; W186-P249 HydrophobicContact CE3-CG 4.17Å; W186-P249 HydrophobicContact CG-CG 4.38Å; W186-P249 HydrophobicContact CZ2-CG 4.47Å; W186-P249 HydrophobicContact CZ3-CG 4.5Å; W186-H252 HydrophobicContact CH2-CB 3.94Å; W186-H252 AromaticContact CH2-CD2 3.59Å; W186-H252 AromaticContact CH2-CG 3.96Å; W186-H252 HydrophobicContact CZ2-CB 4.31Å; W186-I255 HydrophobicContact CH2-CD1 4.38Å; W186-I255 HydrophobicContact CZ3-CD1 4.14Å; W186-I263 HydrophobicContact CE3-CD1 4.28Å
187	A	86.6	Confident	84.1	Confident	0 Å²	0	19.5 Å²	19.5	0%	0	11%	0.106	C	C	.	.			trans	-96.9	113.5	-172.8	0	0	0	0	0	112.8	W183 R192 L195	W183-A187 HydrophobicContact CB-CB 4.43Å; W183-A187 HydrophobicContact CD2-CB 4.46Å; W183-A187 HydrophobicContact CE3-CB 3.7Å; W183-A187 HydrophobicContact CZ3-CB 4.44Å; W183-A187 VanDerWaalsContact O-CB 3.26Å; W183-A187 WeakPolarHBondContact O-CB 3.47Å; W183-A187 PolarHBondContact O-N 3.23Å; A187-R192 HydrophobicContact CB-CB 4.17Å; A187-R192 HydrophobicContact CB-CG 4.09Å; A187-R192 PolarHBondContact O-NH2 3.09Å; A187-L195 HydrophobicContact CB-CD1 3.83Å
188	P	84.6	Confident	84.1	Confident	1 Å²	1	21.7 Å²	21.7	1%	0.006	12%	0.117	C	C	.	.			trans	-57.4	144.6	167.4	-21.9	33.7	0	0	0	111.2	W186 L190 E191 R192 Y262 I263	W186-P188 VanDerWaalsContact O-CD 3.32Å; W186-P188 WeakPolarHBondContact O-CD 3.48Å; P188-L190 VanDerWaalsContact C-N 3.25Å; P188-L190 PolarHBondContact O-N 3.38Å; P188-L190 VanDerWaalsContact O-N 3.1Å; P188-E191 PolarHBondContact O-N 3.49Å; P188-R192 PolarHBondContact O-N 3.08Å; P188-R192 VanDerWaalsContact O-N 3.12Å; P188-Y262 HydrophobicContact CB-CE1 4.15Å; P188-Y262 HydrophobicContact CG-CD1 4.15Å; P188-Y262 HydrophobicContact CG-CE1 3.55Å; P188-I263 HydrophobicContact CG-CG1 4.28Å
189	P	73.8	Confident	84	Confident	52 Å²	52	21.7 Å²	21.7	34%	0.338	12%	0.117	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.4	-35.8	-172.8	-28.4	35.4	0	0	0	114.8	E270	P189-E270 WeakPolarHBondContact CG-OE1 3.21Å
190	L	71.9	Confident	83.8	Confident	119 Å²	119	23.2 Å²	23.2	62%	0.623	12%	0.123	S	C	*	.	T	Hydrogen-bonded Turn	trans	-76	-27.4	-178.5	-64.5	176.3	0	0	0	113.8	P188	P188-L190 VanDerWaalsContact C-N 3.25Å; P188-L190 PolarHBondContact O-N 3.38Å; P188-L190 VanDerWaalsContact O-N 3.1Å
191	E	77.1	Confident	83.8	Confident	21 Å²	21	24.6 Å²	24.6	10%	0.098	13%	0.131	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.7	0.1	-177.9	-56.8	-166	169.1	0	0	112.9	R36 P188 S193 R194 L195	R36-E191 IonicContact CZ-OE1 2.72Å; R36-E191 IonicContact CZ-OE2 3.44Å; R36-E191 IonicContact NE-OE2 3.89Å; R36-E191 PolarHBondContact NE-OE2 3.18Å; R36-E191 VanDerWaalsContact NH2-CD 3.28Å; R36-E191 IonicContact NH2-OE1 3.16Å; R36-E191 PolarHBondContact NH2-OE1 3.39Å; R36-E191 IonicContact NH2-OE2 3.41Å; R36-E191 PolarHBondContact NH2-OE2 2.92Å; P188-E191 PolarHBondContact O-N 3.49Å; E191-S193 PolarHBondContact O-N 3.04Å; E191-R194 PolarHBondContact O-N 3.16Å; E191-R194 IonicContact OE1-NH2 3.91Å; E191-R194 PolarHBondContact OE1-NH2 3.41Å; E191-R194 IonicContact OE2-NH2 3.19Å; E191-R194 PolarHBondContact OE2-NH2 3.21Å; E191-L195 HydrophobicContact CB-CD1 4.33Å; E191-L195 WeakPolarHBondContact O-CG 3.31Å; E191-L195 PolarHBondContact O-N 2.96Å; E191-L195 VanDerWaalsContact O-N 3.11Å
192	R	77.8	Confident	84.1	Confident	10 Å²	10	23.1 Å²	23.1	4%	0.038	12%	0.122	C	C	.	.	H	α-helix	trans	-61.5	-45	-170.2	-176.9	175.5	-70.3	162.5	0.3	113.1	A187 P188 R194 L195 L196 E270 L413	A187-R192 HydrophobicContact CB-CB 4.17Å; A187-R192 HydrophobicContact CB-CG 4.09Å; A187-R192 PolarHBondContact O-NH2 3.09Å; P188-R192 PolarHBondContact O-N 3.08Å; P188-R192 VanDerWaalsContact O-N 3.12Å; R192-R194 VanDerWaalsContact C-N 3.33Å; R192-R194 PolarHBondContact O-N 2.9Å; R192-L195 PolarHBondContact O-N 3.39Å; R192-L196 HydrophobicContact CG-CD1 3.86Å; R192-L196 VanDerWaalsContact O-CD1 3.28Å; R192-L196 WeakPolarHBondContact O-CD1 3.27Å; R192-L196 VanDerWaalsContact O-CG 3.24Å; R192-L196 WeakPolarHBondContact O-CG 3.49Å; R192-L196 PolarHBondContact O-N 3.44Å; R192-L196 VanDerWaalsContact O-N 3.11Å; R192-E270 IonicContact CZ-OE2 2.88Å; R192-E270 IonicContact NH1-OE1 3.76Å; R192-E270 IonicContact NH1-OE2 3.14Å; R192-E270 PolarHBondContact NH1-OE2 3.3Å; R192-E270 VanDerWaalsContact NH1-OE2 3.16Å; R192-E270 IonicContact NH2-OE2 2.97Å; R192-E270 PolarHBondContact NH2-OE2 3.01Å; R192-L413 HydrophobicContact CG-CD1 4.12Å
193	S	74.4	Confident	84.1	Confident	7 Å²	7	23 Å²	23	5%	0.049	12%	0.122	C	C	.	.	H	α-helix	trans	-54.7	-50.5	176.5	48.4	0	0	0	0	110.9	E191 L195 L196 T197 D348	E191-S193 PolarHBondContact O-N 3.04Å; S193-L195 PolarHBondContact O-N 3.18Å; S193-L196 PolarHBondContact O-N 3.25Å; S193-T197 WeakPolarHBondContact O-CB 3.43Å; S193-T197 PolarHBondContact O-N 3.37Å; S193-T197 PolarHBondContact O-OG1 3.36Å; S193-D348 PolarHBondContact OG-OD1 2.99Å; S193-D348 PolarHBondContact OG-OD2 3.02Å
194	R	81.6	Confident	84.1	Confident	81 Å²	81	24.4 Å²	24.4	31%	0.306	13%	0.129	S	C	.	.	H	α-helix	trans	-60.8	-46.7	-179	-175.8	175	64.1	-165.3	-5.7	112.8	Y37 E191 R192 T197 I198	Y37-R194 PolarHBondContact OH-NE 3.39Å; Y37-R194 VanDerWaalsContact OH-NE 3.08Å; Y37-R194 PolarHBondContact OH-NH1 3.48Å; Y37-R194 PolarHBondContact OH-NH2 3.04Å; E191-R194 PolarHBondContact O-N 3.16Å; E191-R194 IonicContact OE1-NH2 3.91Å; E191-R194 PolarHBondContact OE1-NH2 3.41Å; E191-R194 IonicContact OE2-NH2 3.19Å; E191-R194 PolarHBondContact OE2-NH2 3.21Å; R192-R194 VanDerWaalsContact C-N 3.33Å; R192-R194 PolarHBondContact O-N 2.9Å; R194-T197 PolarHBondContact O-N 3.12Å; R194-I198 HydrophobicContact CG-CD1 3.98Å; R194-I198 VanDerWaalsContact O-CG1 3.31Å; R194-I198 WeakPolarHBondContact O-CG1 3.49Å; R194-I198 PolarHBondContact O-N 3.21Å
195	L	86.3	Confident	84.4	Confident	0 Å²	0	27 Å²	27	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-65.4	-40.4	-178	-68.3	168.8	0	0	0	112.3	R36 Y37 A40 W183 A187 E191 R192 S193 S199	R36-L195 HydrophobicContact CG-CD1 4.32Å; R36-L195 HydrophobicContact CG-CD2 4.1Å; Y37-L195 HydrophobicContact CD1-CD2 4.17Å; Y37-L195 HydrophobicContact CE1-CD2 4.36Å; Y37-L195 HydrophobicContact CG-CD2 4.41Å; A40-L195 HydrophobicContact CB-CD2 4.11Å; W183-L195 HydrophobicContact CD2-CB 4.49Å; W183-L195 HydrophobicContact CE3-CB 4.13Å; W183-L195 HydrophobicContact CE3-CD1 4.3Å; W183-L195 HydrophobicContact CH2-CB 3.9Å; W183-L195 HydrophobicContact CH2-CD2 4.17Å; W183-L195 HydrophobicContact CH2-CG 4.4Å; W183-L195 HydrophobicContact CZ2-CB 4.28Å; W183-L195 HydrophobicContact CZ3-CB 3.8Å; W183-L195 HydrophobicContact CZ3-CD1 3.8Å; W183-L195 HydrophobicContact CZ3-CD2 4.26Å; W183-L195 HydrophobicContact CZ3-CG 4.16Å; A187-L195 HydrophobicContact CB-CD1 3.83Å; E191-L195 HydrophobicContact CB-CD1 4.33Å; E191-L195 WeakPolarHBondContact O-CG 3.31Å; E191-L195 PolarHBondContact O-N 2.96Å; E191-L195 VanDerWaalsContact O-N 3.11Å; R192-L195 PolarHBondContact O-N 3.39Å; S193-L195 PolarHBondContact O-N 3.18Å; L195-S199 PolarHBondContact O-N 3.03Å; L195-S199 PolarHBondContact O-OG 2.88Å
196	L	83.7	Confident	84.7	Confident	3 Å²	3	25.7 Å²	25.7	2%	0.016	13%	0.13	C	C	.	.	H	α-helix	trans	-64.8	-46.8	174.5	-64.7	158.7	0	0	0	111	W183 R192 S193 I198 S199 Y200 I410 L413	W183-L196 HydrophobicContact CB-CD2 4.06Å; W183-L196 HydrophobicContact CG-CD2 3.78Å; R192-L196 HydrophobicContact CG-CD1 3.86Å; R192-L196 VanDerWaalsContact O-CD1 3.28Å; R192-L196 WeakPolarHBondContact O-CD1 3.27Å; R192-L196 VanDerWaalsContact O-CG 3.24Å; R192-L196 WeakPolarHBondContact O-CG 3.49Å; R192-L196 PolarHBondContact O-N 3.44Å; R192-L196 VanDerWaalsContact O-N 3.11Å; S193-L196 PolarHBondContact O-N 3.25Å; L196-I198 VanDerWaalsContact C-N 3.32Å; L196-I198 PolarHBondContact O-N 3.08Å; L196-S199 CarbonylContact O-C 3.47Å; L196-S199 WeakPolarHBondContact O-CA 3.24Å; L196-S199 WeakPolarHBondContact O-CB 3.43Å; L196-S199 PolarHBondContact O-N 3.47Å; L196-Y200 HydrophobicContact CB-CD2 4.07Å; L196-Y200 HydrophobicContact CB-CE2 4.15Å; L196-Y200 HydrophobicContact CD2-CD2 4.47Å; L196-Y200 HydrophobicContact CD2-CE2 3.7Å; L196-Y200 WeakPolarHBondContact O-CD2 3.48Å; L196-Y200 PolarHBondContact O-N 3.03Å; L196-I410 HydrophobicContact CD1-CG1 4.44Å; L196-I410 HydrophobicContact CD1-CG2 4.36Å; L196-L413 HydrophobicContact CD1-CD1 3.22Å; L196-L413 HydrophobicContact CD2-CD1 3.95Å; L196-L413 HydrophobicContact CG-CD1 4.17Å
197	T	82.9	Confident	84.7	Confident	24 Å²	24	25.6 Å²	25.6	15%	0.147	13%	0.129	C	C	.	.	H	α-helix	trans	-59.2	-43.7	179.3	-60.5	0	0	0	0	111.3	S193 R194 S199 Y200 I201	S193-T197 WeakPolarHBondContact O-CB 3.43Å; S193-T197 PolarHBondContact O-N 3.37Å; S193-T197 PolarHBondContact O-OG1 3.36Å; R194-T197 PolarHBondContact O-N 3.12Å; T197-S199 VanDerWaalsContact C-N 3.28Å; T197-S199 PolarHBondContact O-N 3.33Å; T197-Y200 PolarHBondContact O-N 3.48Å; T197-I201 WeakPolarHBondContact O-CB 3.42Å; T197-I201 PolarHBondContact O-N 3.35Å
198	I	88.1	Confident	84.9	Confident	46 Å²	46	26.8 Å²	26.8	24%	0.236	14%	0.136	C	C	.	.	H	α-helix	trans	-62.3	-36.4	175.1	-67.3	167	0	0	0	111.4	Y37 A40 L41 S44 R194 L196 I201	Y37-I198 HydrophobicContact CD1-CD1 4.07Å; Y37-I198 HydrophobicContact CE1-CD1 3.97Å; A40-I198 HydrophobicContact CB-CB 4.18Å; A40-I198 HydrophobicContact CB-CG2 3.74Å; L41-I198 HydrophobicContact CD2-CG2 4.14Å; S44-I198 WeakPolarHBondContact CB-O 3.21Å; S44-I198 PolarHBondContact OG-O 2.86Å; R194-I198 HydrophobicContact CG-CD1 3.98Å; R194-I198 VanDerWaalsContact O-CG1 3.31Å; R194-I198 WeakPolarHBondContact O-CG1 3.49Å; R194-I198 PolarHBondContact O-N 3.21Å; L196-I198 VanDerWaalsContact C-N 3.32Å; L196-I198 PolarHBondContact O-N 3.08Å; I198-I201 VanDerWaalsContact O-CG2 3.27Å; I198-I201 WeakPolarHBondContact O-CG2 3.37Å
199	S	90.7	Very high	85.2	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-72.7	-45.2	178.9	-54.7	0	0	0	0	112.4	S44 F47 W183 L195 L196 T197	S44-S199 VanDerWaalsContact CA-O 3.25Å; S44-S199 WeakPolarHBondContact CA-O 3.03Å; F47-S199 WeakPolarHBondContact CD2-O 3.23Å; W183-S199 WeakPolarHBondContact CZ2-OG 3.44Å; W183-S199 PolarHBondContact NE1-OG 3.16Å; L195-S199 PolarHBondContact O-N 3.03Å; L195-S199 PolarHBondContact O-OG 2.88Å; L196-S199 CarbonylContact O-C 3.47Å; L196-S199 WeakPolarHBondContact O-CA 3.24Å; L196-S199 WeakPolarHBondContact O-CB 3.43Å; L196-S199 PolarHBondContact O-N 3.47Å; T197-S199 VanDerWaalsContact C-N 3.28Å; T197-S199 PolarHBondContact O-N 3.33Å
200	Y	88.1	Confident	86.1	Confident	33 Å²	33	27.4 Å²	27.4	13%	0.129	14%	0.139	C	C	.	.	H	α-helix	trans	-83.8	-21.2	-172.7	-70.4	-62.9	0	0	0	113.8	F47 F176 Y180 L196 T197 G202 A203 Q204	F47-Y200 HydrophobicContact CD1-CD1 4.3Å; F47-Y200 HydrophobicContact CD1-CE1 4.36Å; F47-Y200 HydrophobicContact CD2-CD1 4.11Å; F47-Y200 HydrophobicContact CD2-CE1 4.17Å; F47-Y200 HydrophobicContact CE1-CD1 4.14Å; F47-Y200 AromaticContact CE1-CE1 3.76Å; F47-Y200 HydrophobicContact CE1-CE1 3.76Å; F47-Y200 AromaticContact CE2-CD1 3.96Å; F47-Y200 HydrophobicContact CE2-CD1 3.96Å; F47-Y200 AromaticContact CE2-CE1 3.56Å; F47-Y200 HydrophobicContact CE2-CE1 3.56Å; F47-Y200 HydrophobicContact CG-CD1 4.31Å; F47-Y200 AromaticContact CZ-CD1 3.99Å; F47-Y200 HydrophobicContact CZ-CD1 3.99Å; F47-Y200 AromaticContact CZ-CE1 3.33Å; F47-Y200 HydrophobicContact CZ-CE1 3.33Å; F176-Y200 HydrophobicContact CD1-CD1 4.13Å; F176-Y200 AromaticContact CD1-CE1 3.48Å; F176-Y200 HydrophobicContact CD1-CE1 3.48Å; F176-Y200 VanDerWaalsContact CD1-CE1 3.48Å; F176-Y200 AromaticContact CE1-CD1 3.65Å; F176-Y200 HydrophobicContact CE1-CD1 3.65Å; F176-Y200 AromaticContact CE1-CE1 3.49Å; F176-Y200 HydrophobicContact CE1-CE1 3.49Å; F176-Y200 VanDerWaalsContact CE1-CE1 3.49Å; Y180-Y200 HydrophobicContact CD2-CE2 4.34Å; Y180-Y200 AromaticContact CD2-CZ 3.86Å; Y180-Y200 WeakPolarHBondContact CD2-OH 3.32Å; Y180-Y200 HydrophobicContact CE2-CE1 4.41Å; Y180-Y200 AromaticContact CE2-CE2 3.69Å; Y180-Y200 HydrophobicContact CE2-CE2 3.69Å; Y180-Y200 AromaticContact CE2-CZ 3.46Å; Y180-Y200 VanDerWaalsContact CE2-CZ 3.46Å; Y180-Y200 WeakPolarHBondContact CE2-OH 3.37Å; L196-Y200 HydrophobicContact CB-CD2 4.07Å; L196-Y200 HydrophobicContact CB-CE2 4.15Å; L196-Y200 HydrophobicContact CD2-CD2 4.47Å; L196-Y200 HydrophobicContact CD2-CE2 3.7Å; L196-Y200 WeakPolarHBondContact O-CD2 3.48Å; L196-Y200 PolarHBondContact O-N 3.03Å; T197-Y200 PolarHBondContact O-N 3.48Å; Y200-G202 PolarHBondContact O-N 3.03Å; Y200-A203 WeakPolarHBondContact O-CB 3.43Å; Y200-A203 PolarHBondContact O-N 3.48Å; Y200-Q204 PolarHBondContact O-OE1 2.93Å
201	I	88.4	Confident	86.8	Confident	40 Å²	40	21.9 Å²	21.9	21%	0.205	11%	0.11	C	C	.	.	H	α-helix	trans	-55.8	-27.3	172.7	-159.1	-172.6	0	0	0	111.9	T197 I198 A203 Q204 L205 A337 V341	T197-I201 WeakPolarHBondContact O-CB 3.42Å; T197-I201 PolarHBondContact O-N 3.35Å; I198-I201 VanDerWaalsContact O-CG2 3.27Å; I198-I201 WeakPolarHBondContact O-CG2 3.37Å; I201-A203 VanDerWaalsContact C-N 3.26Å; I201-A203 PolarHBondContact O-N 3.49Å; I201-Q204 PolarHBondContact O-N 3.07Å; I201-L205 HydrophobicContact CD1-CD1 4.47Å; I201-L205 HydrophobicContact CG1-CD1 4.44Å; I201-L205 HydrophobicContact CG1-CG 4.39Å; I201-L205 HydrophobicContact CG2-CD1 4.36Å; I201-L205 WeakPolarHBondContact O-CG 3.23Å; I201-L205 PolarHBondContact O-N 2.85Å; I201-A337 HydrophobicContact CG1-CB 4.36Å; I201-V341 HydrophobicContact CD1-CG2 3.25Å; I201-V341 HydrophobicContact CG1-CG2 4.09Å
202	G	91.9	Very high	87.4	Confident	1 Å²	1	21.7 Å²	21.7	1%	0.01	11%	0.111	C	C	.	.	H	α-helix	trans	-52.7	-41.7	174.3	0	0	0	0	0	112.9	S44 F48 Y200 Q204 L205 G206	S44-G202 VanDerWaalsContact O-CA 3.28Å; S44-G202 WeakPolarHBondContact O-CA 3.28Å; S44-G202 WeakPolarHBondContact OG-CA 3.43Å; S44-G202 PolarHBondContact OG-N 2.93Å; F48-G202 WeakPolarHBondContact CA-O 3.35Å; F48-G202 PolarHBondContact N-O 3.41Å; Y200-G202 PolarHBondContact O-N 3.03Å; G202-Q204 VanDerWaalsContact C-N 3.33Å; G202-Q204 PolarHBondContact O-N 3.35Å; G202-L205 PolarHBondContact O-N 2.91Å; G202-G206 PolarHBondContact O-N 3.49Å
203	A	90.7	Very high	88	Confident	2 Å²	2	25 Å²	25	2%	0.017	13%	0.129	C	C	.	.	H	α-helix	trans	-59.2	-43.7	179.3	0	0	0	0	0	112.4	F47 Y51 Y200 I201 G206 T207	F47-A203 HydrophobicContact CB-CB 4.16Å; F47-A203 WeakPolarHBondContact O-CA 3.5Å; Y51-A203 WeakPolarHBondContact CB-O 3.37Å; Y51-A203 HydrophobicContact CD1-CB 4.16Å; Y51-A203 HydrophobicContact CD2-CB 3.26Å; Y51-A203 HydrophobicContact CE1-CB 4.23Å; Y51-A203 HydrophobicContact CE2-CB 3.36Å; Y51-A203 HydrophobicContact CG-CB 3.68Å; Y200-A203 WeakPolarHBondContact O-CB 3.43Å; Y200-A203 PolarHBondContact O-N 3.48Å; I201-A203 VanDerWaalsContact C-N 3.26Å; I201-A203 PolarHBondContact O-N 3.49Å; A203-G206 PolarHBondContact O-N 2.98Å; A203-T207 PolarHBondContact O-N 3.23Å; A203-T207 VanDerWaalsContact O-N 3.13Å; A203-T207 PolarHBondContact O-OG1 3.36Å
204	Q	87.6	Confident	88.7	Confident	29 Å²	29	24.6 Å²	24.6	14%	0.136	13%	0.126	C	C	.	.	H	α-helix	trans	-72.2	-42.9	179.9	-84.5	51.7	35.7	0	0	110.5	Y200 I201 G202 G206 T207 V208 A337	Y200-Q204 PolarHBondContact O-OE1 2.93Å; I201-Q204 PolarHBondContact O-N 3.07Å; G202-Q204 VanDerWaalsContact C-N 3.33Å; G202-Q204 PolarHBondContact O-N 3.35Å; Q204-G206 VanDerWaalsContact C-N 3.29Å; Q204-G206 PolarHBondContact O-N 3.16Å; Q204-T207 WeakPolarHBondContact O-CB 3.18Å; Q204-T207 PolarHBondContact O-N 3.14Å; Q204-V208 VanDerWaalsContact O-CG2 3.25Å; Q204-V208 WeakPolarHBondContact O-CG2 3.44Å; Q204-V208 PolarHBondContact O-N 3.3Å; Q204-A337 HydrophobicContact CB-CB 3.77Å; Q204-A337 HydrophobicContact CG-CB 4.42Å
205	L	90.4	Very high	88.9	Confident	68 Å²	68	20.8 Å²	20.8	36%	0.356	11%	0.112	S	C	.	.	H	α-helix	trans	-61	-39.7	174.3	-67.6	176.5	0	0	0	111.8	F48 I201 G202 T207 V208 V209	F48-L205 HydrophobicContact CD2-CB 3.99Å; F48-L205 HydrophobicContact CE2-CB 4.47Å; I201-L205 HydrophobicContact CD1-CD1 4.47Å; I201-L205 HydrophobicContact CG1-CD1 4.44Å; I201-L205 HydrophobicContact CG1-CG 4.39Å; I201-L205 HydrophobicContact CG2-CD1 4.36Å; I201-L205 WeakPolarHBondContact O-CG 3.23Å; I201-L205 PolarHBondContact O-N 2.85Å; G202-L205 PolarHBondContact O-N 2.91Å; L205-T207 VanDerWaalsContact C-N 3.3Å; L205-T207 PolarHBondContact O-N 3.17Å; L205-V208 PolarHBondContact O-N 3.26Å; L205-V209 WeakPolarHBondContact O-CG2 3.44Å; L205-V209 PolarHBondContact O-N 3.49Å
206	G	92.2	Very high	89	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-58.7	-42.9	175.3	0	0	0	0	0	111.9	F48 S52 G202 A203 Q204 A210	F48-G206 WeakPolarHBondContact O-CA 3.38Å; S52-G206 PolarHBondContact OG-O 2.91Å; S52-G206 VanDerWaalsContact OG-O 3.12Å; G202-G206 PolarHBondContact O-N 3.49Å; A203-G206 PolarHBondContact O-N 2.98Å; Q204-G206 VanDerWaalsContact C-N 3.29Å; Q204-G206 PolarHBondContact O-N 3.16Å; G206-A210 WeakPolarHBondContact O-CB 3.25Å; G206-A210 PolarHBondContact O-N 3.34Å
207	T	89.4	Confident	89.3	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-67.1	-47.1	175.5	-54.7	0	0	0	0	111.9	Y51 V55 A203 Q204 L205 V209 A210 L211 L307 Y333	Y51-T207 WeakPolarHBondContact CD1-OG1 3.33Å; V55-T207 HydrophobicContact CG1-CG2 4.13Å; A203-T207 PolarHBondContact O-N 3.23Å; A203-T207 VanDerWaalsContact O-N 3.13Å; A203-T207 PolarHBondContact O-OG1 3.36Å; Q204-T207 WeakPolarHBondContact O-CB 3.18Å; Q204-T207 PolarHBondContact O-N 3.14Å; L205-T207 VanDerWaalsContact C-N 3.3Å; L205-T207 PolarHBondContact O-N 3.17Å; T207-V209 VanDerWaalsContact C-N 3.28Å; T207-V209 PolarHBondContact O-N 3.38Å; T207-A210 PolarHBondContact O-N 3.05Å; T207-L211 HydrophobicContact CG2-CD1 3.74Å; T207-L211 HydrophobicContact CG2-CG 4.19Å; T207-L211 WeakPolarHBondContact O-CG 3.07Å; T207-L211 PolarHBondContact O-N 3.43Å; T207-L211 VanDerWaalsContact O-N 3.07Å; T207-L307 HydrophobicContact CG2-CD1 4.09Å; T207-Y333 HydrophobicContact CG2-CD1 4.04Å; T207-Y333 HydrophobicContact CG2-CD2 3.67Å; T207-Y333 HydrophobicContact CG2-CE1 4.47Å; T207-Y333 HydrophobicContact CG2-CE2 4.13Å; T207-Y333 HydrophobicContact CG2-CG 3.65Å
208	V	90.6	Very high	89.4	Confident	25 Å²	25	23.7 Å²	23.7	15%	0.152	12%	0.124	C	C	.	.	H	α-helix	trans	-60.4	-37.5	-179.2	169.5	0	0	0	0	112	Q204 L205 P212 L334	Q204-V208 VanDerWaalsContact O-CG2 3.25Å; Q204-V208 WeakPolarHBondContact O-CG2 3.44Å; Q204-V208 PolarHBondContact O-N 3.3Å; L205-V208 PolarHBondContact O-N 3.26Å; V208-P212 WeakPolarHBondContact O-CD 3.43Å; V208-P212 WeakPolarHBondContact O-CG 3.25Å; V208-L334 HydrophobicContact CG1-CB 4.25Å; V208-L334 HydrophobicContact CG1-CD1 4.34Å; V208-L334 HydrophobicContact CG2-CB 3.87Å; V208-L334 VanDerWaalsContact CG2-N 3.28Å
209	V	92.4	Very high	89.1	Confident	66 Å²	66	23.4 Å²	23.4	40%	0.4	12%	0.121	S	C	.	.	H	α-helix	trans	-83.5	-40.9	178.3	175.9	0	0	0	0	111.3	F48 L205 T207 P212 L213	F48-V209 HydrophobicContact CE2-CB 3.86Å; F48-V209 HydrophobicContact CE2-CG1 4.39Å; F48-V209 HydrophobicContact CE2-CG2 3.88Å; F48-V209 HydrophobicContact CZ-CB 3.9Å; F48-V209 HydrophobicContact CZ-CG1 3.97Å; F48-V209 HydrophobicContact CZ-CG2 4.29Å; L205-V209 WeakPolarHBondContact O-CG2 3.44Å; L205-V209 PolarHBondContact O-N 3.49Å; T207-V209 VanDerWaalsContact C-N 3.28Å; T207-V209 PolarHBondContact O-N 3.38Å; V209-P212 WeakPolarHBondContact O-CD 3.41Å; V209-L213 HydrophobicContact CG1-CD2 4.45Å; V209-L213 WeakPolarHBondContact O-CB 3.47Å; V209-L213 PolarHBondContact O-N 3Å
210	A	91.6	Very high	88.9	Confident	0 Å²	0	30 Å²	30	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-69.9	-35.9	-174.2	0	0	0	0	0	113.5	V55 G206 T207 S214 F230	V55-A210 HydrophobicContact CG2-CB 3.58Å; G206-A210 WeakPolarHBondContact O-CB 3.25Å; G206-A210 PolarHBondContact O-N 3.34Å; T207-A210 PolarHBondContact O-N 3.05Å; A210-S214 WeakPolarHBondContact O-CB 3.5Å; A210-S214 PolarHBondContact O-N 2.79Å; A210-S214 PolarHBondContact O-OG 2.88Å; A210-F230 HydrophobicContact CB-CE1 4.02Å; A210-F230 HydrophobicContact CB-CE2 4.41Å; A210-F230 HydrophobicContact CB-CZ 3.75Å
211	L	87.7	Confident	88.8	Confident	3 Å²	3	33.1 Å²	33.1	2%	0.016	16%	0.164	C	C	.	.	H	α-helix	trans	-62.8	-54.2	-179	-68.4	172.4	0	0	0	112.5	V55 V59 T207 S214 G215 Y333	V55-L211 HydrophobicContact CB-CD2 4.14Å; V55-L211 HydrophobicContact CG2-CD2 4.18Å; V55-L211 HydrophobicContact CG2-CG 4.33Å; V59-L211 HydrophobicContact CG2-CD2 3.53Å; T207-L211 HydrophobicContact CG2-CD1 3.74Å; T207-L211 HydrophobicContact CG2-CG 4.19Å; T207-L211 WeakPolarHBondContact O-CG 3.07Å; T207-L211 PolarHBondContact O-N 3.43Å; T207-L211 VanDerWaalsContact O-N 3.07Å; L211-S214 PolarHBondContact O-N 3.46Å; L211-G215 PolarHBondContact O-N 3.39Å; L211-Y333 HydrophobicContact CD1-CD2 3.87Å; L211-Y333 HydrophobicContact CD1-CE2 3.83Å
212	P	88.6	Confident	88.7	Confident	18 Å²	18	31.4 Å²	31.4	12%	0.117	16%	0.156	C	C	.	.	H	α-helix	trans	-66.4	-41.3	177.1	-17.5	31.2	0	0	0	112.2	V208 V209 S214 G215 E216 F327 A330	V208-P212 WeakPolarHBondContact O-CD 3.43Å; V208-P212 WeakPolarHBondContact O-CG 3.25Å; V209-P212 WeakPolarHBondContact O-CD 3.41Å; P212-S214 VanDerWaalsContact C-N 3.32Å; P212-S214 PolarHBondContact O-N 2.91Å; P212-G215 PolarHBondContact O-N 2.77Å; P212-G215 VanDerWaalsContact O-N 3.15Å; P212-E216 PolarHBondContact O-N 3.2Å; P212-F327 HydrophobicContact CB-CD1 4.1Å; P212-F327 HydrophobicContact CB-CD2 4.43Å; P212-F327 HydrophobicContact CB-CE1 4.09Å; P212-F327 HydrophobicContact CB-CE2 4.41Å; P212-F327 HydrophobicContact CB-CG 4.27Å; P212-F327 HydrophobicContact CB-CZ 4.25Å; P212-F327 HydrophobicContact CG-CD1 4.4Å; P212-A330 HydrophobicContact CG-CB 3.75Å
213	L	91.2	Very high	88.7	Confident	78 Å²	78	31.5 Å²	31.5	41%	0.408	16%	0.156	S	C	.	.	H	α-helix	trans	-63.1	-39.2	-179.2	-176.2	58.9	0	0	0	111.5	V209 E216 I217 F230	V209-L213 HydrophobicContact CG1-CD2 4.45Å; V209-L213 WeakPolarHBondContact O-CB 3.47Å; V209-L213 PolarHBondContact O-N 3Å; L213-E216 PolarHBondContact O-N 3.05Å; L213-I217 HydrophobicContact CD1-CD1 4.06Å; L213-I217 HydrophobicContact CD1-CG1 4.28Å; L213-I217 HydrophobicContact CG-CD1 3.76Å; L213-I217 HydrophobicContact CG-CG1 4.44Å; L213-I217 WeakPolarHBondContact O-CB 3.27Å; L213-I217 WeakPolarHBondContact O-CD1 3.3Å; L213-I217 WeakPolarHBondContact O-CG1 3.14Å; L213-I217 PolarHBondContact O-N 3.03Å; L213-F230 HydrophobicContact CB-CZ 4.35Å; L213-F230 HydrophobicContact CD2-CE1 4.19Å; L213-F230 HydrophobicContact CD2-CZ 3.85Å; L213-F230 HydrophobicContact CG-CZ 4.21Å
214	S	89.6	Confident	88.8	Confident	0 Å²	0	32.5 Å²	32.5	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-63.1	-42.9	174	-58	0	0	0	0	111.4	A210 L211 P212 E216 I217 C218 V226 F230	A210-S214 WeakPolarHBondContact O-CB 3.5Å; A210-S214 PolarHBondContact O-N 2.79Å; A210-S214 PolarHBondContact O-OG 2.88Å; L211-S214 PolarHBondContact O-N 3.46Å; P212-S214 VanDerWaalsContact C-N 3.32Å; P212-S214 PolarHBondContact O-N 2.91Å; S214-E216 VanDerWaalsContact C-N 3.33Å; S214-E216 PolarHBondContact O-N 3.29Å; S214-I217 PolarHBondContact O-N 3.01Å; S214-C218 WeakPolarHBondContact O-CB 3.01Å; S214-C218 PolarHBondContact O-N 3.08Å; S214-C218 PolarHBondContact O-SG 3.29Å; S214-V226 WeakPolarHBondContact OG-CG1 3.49Å; S214-F230 WeakPolarHBondContact OG-CE2 3.06Å
215	G	84.6	Confident	89.1	Confident	1 Å²	1	36.8 Å²	36.8	1%	0.01	18%	0.178	C	C	.	.	H	α-helix	trans	-61	-41	177.1	0	0	0	0	0	112.9	L211 P212 F219	L211-G215 PolarHBondContact O-N 3.39Å; P212-G215 PolarHBondContact O-N 2.77Å; P212-G215 VanDerWaalsContact O-N 3.15Å; G215-F219 PolarHBondContact O-N 3.37Å; G215-F219 VanDerWaalsContact O-N 3.12Å
216	E	87.8	Confident	89.3	Confident	72 Å²	72	33.5 Å²	33.5	34%	0.336	16%	0.161	S	C	.	.	H	α-helix	trans	-69.7	-43.7	177.6	-162.8	73.4	167.6	0	0	112	P212 L213 S214 F219 Y220	P212-E216 PolarHBondContact O-N 3.2Å; L213-E216 PolarHBondContact O-N 3.05Å; S214-E216 VanDerWaalsContact C-N 3.33Å; S214-E216 PolarHBondContact O-N 3.29Å; E216-F219 PolarHBondContact O-N 3.39Å; E216-F219 VanDerWaalsContact O-N 3.14Å; E216-Y220 HydrophobicContact CG-CD2 4.01Å; E216-Y220 HydrophobicContact CG-CE2 4.05Å; E216-Y220 WeakPolarHBondContact O-CD2 3.48Å; E216-Y220 PolarHBondContact O-N 3.24Å; E216-Y220 VanDerWaalsContact O-N 3.1Å; E216-Y220 WeakPolarHBondContact OE1-CE2 3.42Å
217	I	90.3	Very high	89.5	Confident	13 Å²	13	33.5 Å²	33.5	7%	0.067	16%	0.161	C	C	.	.	H	α-helix	trans	-61.7	-45.7	176.5	-68.4	161.5	0	0	0	110.4	L213 S214 F219 Y220 M221 G222 V226 L229	L213-I217 HydrophobicContact CD1-CD1 4.06Å; L213-I217 HydrophobicContact CD1-CG1 4.28Å; L213-I217 HydrophobicContact CG-CD1 3.76Å; L213-I217 HydrophobicContact CG-CG1 4.44Å; L213-I217 WeakPolarHBondContact O-CB 3.27Å; L213-I217 WeakPolarHBondContact O-CD1 3.3Å; L213-I217 WeakPolarHBondContact O-CG1 3.14Å; L213-I217 PolarHBondContact O-N 3.03Å; S214-I217 PolarHBondContact O-N 3.01Å; I217-F219 PolarHBondContact O-N 3.24Å; I217-Y220 PolarHBondContact O-N 2.77Å; I217-M221 HydrophobicContact CG2-CB 4.3Å; I217-M221 WeakPolarHBondContact O-CA 3.2Å; I217-M221 WeakPolarHBondContact O-CB 3.18Å; I217-M221 PolarHBondContact O-N 3.46Å; I217-G222 PolarHBondContact O-N 3.06Å; I217-G222 VanDerWaalsContact O-N 3.13Å; I217-V226 HydrophobicContact CB-CG2 3.96Å; I217-V226 HydrophobicContact CG2-CB 4.46Å; I217-V226 HydrophobicContact CG2-CG2 3.64Å; I217-L229 HydrophobicContact CD1-CD1 3.62Å; I217-L229 HydrophobicContact CG1-CD1 4.09Å; I217-L229 HydrophobicContact CG2-CD1 4.45Å
218	C	85.8	Confident	89.8	Confident	2 Å²	2	38.4 Å²	38.4	1%	0.014	18%	0.18	C	C	.	.	H	α-helix	trans	-56	-42.5	174.8	-70.8	0	0	0	0	110.8	D63 S214 G222	D63-C218 HydrophobicContact CB-CB 4.37Å; S214-C218 WeakPolarHBondContact O-CB 3.01Å; S214-C218 PolarHBondContact O-N 3.08Å; S214-C218 PolarHBondContact O-SG 3.29Å; C218-G222 WeakPolarHBondContact O-CA 3.44Å; C218-G222 PolarHBondContact O-N 3.43Å
219	F	82.1	Confident	90	Very high	40 Å²	40	41.2 Å²	41.2	18%	0.175	19%	0.194	C	C	.	.	H	α-helix	trans	-64.6	-43.2	-178.7	-171.2	-96.7	0	0	0	115.2	P89 H91 G215 E216 I217 Q323	P89-F219 HydrophobicContact CB-CE2 4.42Å; P89-F219 HydrophobicContact CB-CZ 4.1Å; P89-F219 HydrophobicContact CG-CE2 3.86Å; P89-F219 HydrophobicContact CG-CZ 3.88Å; H91-F219 AromaticContact CE1-CD2 3.91Å; H91-F219 AromaticContact ND1-CD2 3.55Å; H91-F219 AromaticContact ND1-CE2 3.92Å; G215-F219 PolarHBondContact O-N 3.37Å; G215-F219 VanDerWaalsContact O-N 3.12Å; E216-F219 PolarHBondContact O-N 3.39Å; E216-F219 VanDerWaalsContact O-N 3.14Å; I217-F219 PolarHBondContact O-N 3.24Å; F219-Q323 VanDerWaalsContact CD1-NE2 3.32Å; F219-Q323 HydrophobicContact CD2-CG 4.43Å; F219-Q323 HydrophobicContact CG-CG 4.5Å
220	Y	85.4	Confident	90.2	Very high	139 Å²	139	38.7 Å²	38.7	55%	0.545	18%	0.178	S	C	.	.	H	α-helix	trans	-97.7	-32.1	-174.5	-71.1	-77.1	0	0	0	114.6	E216 I217	E216-Y220 HydrophobicContact CG-CD2 4.01Å; E216-Y220 HydrophobicContact CG-CE2 4.05Å; E216-Y220 WeakPolarHBondContact O-CD2 3.48Å; E216-Y220 PolarHBondContact O-N 3.24Å; E216-Y220 VanDerWaalsContact O-N 3.1Å; E216-Y220 WeakPolarHBondContact OE1-CE2 3.42Å; I217-Y220 PolarHBondContact O-N 2.77Å
221	M	86.4	Confident	90.5	Very high	99 Å²	99	38.7 Å²	38.7	49%	0.488	18%	0.178	S	C	.	.	H	α-helix	trans	-118	-18	-170	-55.2	-177.8	-177.9	0	0	112.7	I217 Y225	I217-M221 HydrophobicContact CG2-CB 4.3Å; I217-M221 WeakPolarHBondContact O-CA 3.2Å; I217-M221 WeakPolarHBondContact O-CB 3.18Å; I217-M221 PolarHBondContact O-N 3.46Å; M221-Y225 HydrophobicContact CB-CD2 3.71Å; M221-Y225 HydrophobicContact CB-CE2 4.32Å; M221-Y225 HydrophobicContact CB-CG 3.89Å; M221-Y225 WeakPolarHBondContact O-CD2 3.25Å; M221-Y225 VanDerWaalsContact O-CE2 3.3Å; M221-Y225 WeakPolarHBondContact O-CE2 3.24Å
222	G	87	Confident	90.9	Very high	3 Å²	3	40.8 Å²	40.8	3%	0.031	20%	0.196	C	C	.	.			trans	89.6	157.6	-174.1	0	0	0	0	0	113	I217 C218 P224 Y225	I217-G222 PolarHBondContact O-N 3.06Å; I217-G222 VanDerWaalsContact O-N 3.13Å; C218-G222 WeakPolarHBondContact O-CA 3.44Å; C218-G222 PolarHBondContact O-N 3.43Å; G222-P224 WeakPolarHBondContact O-CD 3.17Å; G222-Y225 PolarHBondContact O-N 2.79Å
223	W	90.4	Very high	91.3	Very high	4 Å²	4	42.6 Å²	42.6	2%	0.015	21%	0.206	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53.8	-32.3	-175.2	69.2	-100.4	0	0	0	116.9	A60 D63 M64 A95 G96 Y98 P151 A154 Y225 V226 F227	A60-W223 HydrophobicContact CB-CB 4.28Å; D63-W223 HydrophobicContact CB-CB 4.27Å; D63-W223 PolarHBondContact OD2-N 3.14Å; M64-W223 HydrophobicContact CE-CD2 4.48Å; M64-W223 HydrophobicContact CE-CE3 4.17Å; M64-W223 HydrophobicContact CE-CH2 4.07Å; M64-W223 HydrophobicContact CE-CZ2 4.38Å; M64-W223 HydrophobicContact CE-CZ3 3.94Å; M64-W223 HydrophobicContact CG-CB 4.26Å; M64-W223 HydrophobicContact CG-CD2 3.58Å; M64-W223 HydrophobicContact CG-CE3 4.01Å; M64-W223 HydrophobicContact CG-CG 3.69Å; M64-W223 HydrophobicContact SD-CD2 4.3Å; M64-W223 HydrophobicContact SD-CE3 4.11Å; M64-W223 HydrophobicContact SD-CZ3 4.44Å; A95-W223 HydrophobicContact CB-CG 4.4Å; G96-W223 PolarHBondContact O-NE1 3.47Å; Y98-W223 HydrophobicContact CE2-CH2 4.2Å; Y98-W223 AromaticContact CE2-CZ2 3.62Å; Y98-W223 HydrophobicContact CE2-CZ2 3.62Å; P151-W223 HydrophobicContact CB-CH2 4.06Å; P151-W223 HydrophobicContact CB-CZ3 3.87Å; P151-W223 HydrophobicContact CG-CZ3 4.16Å; A154-W223 HydrophobicContact CB-CH2 3.81Å; A154-W223 HydrophobicContact CB-CZ3 4.38Å; W223-Y225 VanDerWaalsContact C-N 3.27Å; W223-Y225 PolarHBondContact O-N 3.33Å; W223-V226 WeakPolarHBondContact O-CB 3.13Å; W223-V226 WeakPolarHBondContact O-CG2 3.24Å; W223-V226 PolarHBondContact O-N 2.94Å; W223-F227 AromaticContact CE3-CD2 3.91Å; W223-F227 HydrophobicContact CE3-CD2 3.91Å; W223-F227 AromaticContact CE3-CE2 3.6Å; W223-F227 HydrophobicContact CE3-CE2 3.6Å; W223-F227 HydrophobicContact CZ3-CD2 4.04Å; W223-F227 AromaticContact CZ3-CE2 3.89Å; W223-F227 HydrophobicContact CZ3-CE2 3.89Å
224	P	93.8	Very high	91.6	Very high	23 Å²	23	38.9 Å²	38.9	15%	0.149	19%	0.187	C	C	.	.	H	α-helix	trans	-61.8	-34.3	-177.2	-26.1	36.9	0	0	0	113.3	A95 P151 G222 V226 F227 Y228	A95-P224 HydrophobicContact CB-CG 4.03Å; P151-P224 HydrophobicContact CB-CB 4.07Å; P151-P224 HydrophobicContact CG-CB 4.11Å; G222-P224 WeakPolarHBondContact O-CD 3.17Å; P224-V226 PolarHBondContact O-N 2.92Å; P224-F227 PolarHBondContact O-N 3.47Å; P224-F227 VanDerWaalsContact O-N 3.17Å; P224-Y228 HydrophobicContact CB-CE2 4.04Å; P224-Y228 WeakPolarHBondContact O-CD2 3.48Å; P224-Y228 PolarHBondContact O-N 2.66Å
225	Y	93.9	Very high	92	Very high	118 Å²	118	41 Å²	41	46%	0.463	20%	0.2	S	C	.	.	H	α-helix	trans	-67.7	-23.7	-177.6	-74.9	-86.4	0	0	0	113.4	M221 G222 W223 F227 Y228 L229	M221-Y225 HydrophobicContact CB-CD2 3.71Å; M221-Y225 HydrophobicContact CB-CE2 4.32Å; M221-Y225 HydrophobicContact CB-CG 3.89Å; M221-Y225 WeakPolarHBondContact O-CD2 3.25Å; M221-Y225 VanDerWaalsContact O-CE2 3.3Å; M221-Y225 WeakPolarHBondContact O-CE2 3.24Å; G222-Y225 PolarHBondContact O-N 2.79Å; W223-Y225 VanDerWaalsContact C-N 3.27Å; W223-Y225 PolarHBondContact O-N 3.33Å; Y225-F227 VanDerWaalsContact C-N 3.28Å; Y225-F227 PolarHBondContact O-N 2.81Å; Y225-Y228 HydrophobicContact CD1-CD2 4.46Å; Y225-Y228 PolarHBondContact O-N 3.11Å; Y225-L229 WeakPolarHBondContact O-CB 3.49Å; Y225-L229 VanDerWaalsContact O-CG 3.32Å; Y225-L229 WeakPolarHBondContact O-CG 3.28Å; Y225-L229 PolarHBondContact O-N 3.49Å
226	V	94.2	Very high	92.6	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-57.5	-48.3	173.3	-175.8	0	0	0	0	109.2	N56 S214 I217 W223 P224 F230	N56-V226 HydrophobicContact CB-CG1 3.65Å; S214-V226 WeakPolarHBondContact OG-CG1 3.49Å; I217-V226 HydrophobicContact CB-CG2 3.96Å; I217-V226 HydrophobicContact CG2-CB 4.46Å; I217-V226 HydrophobicContact CG2-CG2 3.64Å; W223-V226 WeakPolarHBondContact O-CB 3.13Å; W223-V226 WeakPolarHBondContact O-CG2 3.24Å; W223-V226 PolarHBondContact O-N 2.94Å; P224-V226 PolarHBondContact O-N 2.92Å; V226-F230 HydrophobicContact CG1-CD2 3.8Å; V226-F230 HydrophobicContact CG1-CE2 3.84Å; V226-F230 WeakPolarHBondContact O-CD2 3.35Å; V226-F230 PolarHBondContact O-N 3.11Å
227	F	95.9	Very high	93	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-70.2	-39.5	-178.7	-59.2	-62.6	0	0	0	112.4	N56 L57 A60 M64 T147 T150 P151 W223 P224 Y225 G231	N56-F227 HydrophobicContact CB-CE1 4.31Å; N56-F227 WeakPolarHBondContact OD1-CE1 3.41Å; L57-F227 HydrophobicContact CB-CE1 4.24Å; L57-F227 HydrophobicContact CB-CZ 4.33Å; L57-F227 HydrophobicContact CD1-CE1 4.37Å; L57-F227 HydrophobicContact CD1-CZ 3.75Å; A60-F227 HydrophobicContact CB-CE2 4.01Å; A60-F227 HydrophobicContact CB-CZ 3.74Å; M64-F227 HydrophobicContact SD-CE2 4.49Å; T147-F227 HydrophobicContact CG2-CB 4.13Å; T147-F227 HydrophobicContact CG2-CD1 3.89Å; T147-F227 WeakPolarHBondContact O-CB 3.24Å; T150-F227 HydrophobicContact CG2-CD1 3.82Å; T150-F227 HydrophobicContact CG2-CD2 3.73Å; T150-F227 HydrophobicContact CG2-CE1 3.78Å; T150-F227 HydrophobicContact CG2-CE2 3.63Å; T150-F227 HydrophobicContact CG2-CG 3.81Å; T150-F227 HydrophobicContact CG2-CZ 3.67Å; P151-F227 HydrophobicContact CG-CB 3.95Å; P151-F227 HydrophobicContact CG-CD2 3.97Å; P151-F227 HydrophobicContact CG-CG 4.35Å; W223-F227 AromaticContact CE3-CD2 3.91Å; W223-F227 HydrophobicContact CE3-CD2 3.91Å; W223-F227 AromaticContact CE3-CE2 3.6Å; W223-F227 HydrophobicContact CE3-CE2 3.6Å; W223-F227 HydrophobicContact CZ3-CD2 4.04Å; W223-F227 AromaticContact CZ3-CE2 3.89Å; W223-F227 HydrophobicContact CZ3-CE2 3.89Å; P224-F227 PolarHBondContact O-N 3.47Å; P224-F227 VanDerWaalsContact O-N 3.17Å; Y225-F227 VanDerWaalsContact C-N 3.28Å; Y225-F227 PolarHBondContact O-N 2.81Å; F227-G231 PolarHBondContact O-N 3.45Å
228	Y	96.2	Very high	93.4	Very high	103 Å²	103	42.2 Å²	42.2	40%	0.404	21%	0.21	S	C	.	.	H	α-helix	trans	-64.3	-45	177.3	-62.2	-39	0	0	0	113.1	L148 P151 P224 Y225 A232	L148-Y228 HydrophobicContact CD2-CD1 4.21Å; L148-Y228 WeakPolarHBondContact CD2-O 3.47Å; L148-Y228 WeakPolarHBondContact O-CE1 3.07Å; P151-Y228 HydrophobicContact CB-CE1 4.46Å; P151-Y228 HydrophobicContact CG-CD1 4.47Å; P151-Y228 HydrophobicContact CG-CE1 3.83Å; P151-Y228 HydrophobicContact CG-CE2 4.39Å; P224-Y228 HydrophobicContact CB-CE2 4.04Å; P224-Y228 WeakPolarHBondContact O-CD2 3.48Å; P224-Y228 PolarHBondContact O-N 2.66Å; Y225-Y228 HydrophobicContact CD1-CD2 4.46Å; Y225-Y228 PolarHBondContact O-N 3.11Å; Y228-A232 VanDerWaalsContact O-CB 3.27Å; Y228-A232 WeakPolarHBondContact O-CB 3.33Å; Y228-A232 PolarHBondContact O-N 3.27Å
229	L	96	Very high	93.9	Very high	83 Å²	83	45.4 Å²	45.4	44%	0.435	23%	0.229	S	C	.	.	H	α-helix	trans	-68.1	-51	-178.5	-71	171.5	0	0	0	111.6	I217 Y225 G231 A232 V233	I217-L229 HydrophobicContact CD1-CD1 3.62Å; I217-L229 HydrophobicContact CG1-CD1 4.09Å; I217-L229 HydrophobicContact CG2-CD1 4.45Å; Y225-L229 WeakPolarHBondContact O-CB 3.49Å; Y225-L229 VanDerWaalsContact O-CG 3.32Å; Y225-L229 WeakPolarHBondContact O-CG 3.28Å; Y225-L229 PolarHBondContact O-N 3.49Å; L229-G231 PolarHBondContact O-N 3.38Å; L229-A232 PolarHBondContact O-N 2.98Å; L229-V233 WeakPolarHBondContact O-CG2 3.46Å; L229-V233 PolarHBondContact O-N 2.68Å; L229-V233 VanDerWaalsContact O-N 3.08Å
230	F	95.9	Very high	94.5	Very high	13 Å²	13	46.9 Å²	46.9	6%	0.057	24%	0.238	C	C	.	.	H	α-helix	trans	-66.7	-38.5	179.6	-72	-63.4	0	0	0	112.3	L53 N56 A210 L213 S214 V226 V233 G234	L53-F230 HydrophobicContact CD2-CB 3.93Å; L53-F230 WeakPolarHBondContact CD2-O 3.33Å; N56-F230 HydrophobicContact CB-CD2 4.15Å; A210-F230 HydrophobicContact CB-CE1 4.02Å; A210-F230 HydrophobicContact CB-CE2 4.41Å; A210-F230 HydrophobicContact CB-CZ 3.75Å; L213-F230 HydrophobicContact CB-CZ 4.35Å; L213-F230 HydrophobicContact CD2-CE1 4.19Å; L213-F230 HydrophobicContact CD2-CZ 3.85Å; L213-F230 HydrophobicContact CG-CZ 4.21Å; S214-F230 WeakPolarHBondContact OG-CE2 3.06Å; V226-F230 HydrophobicContact CG1-CD2 3.8Å; V226-F230 HydrophobicContact CG1-CE2 3.84Å; V226-F230 WeakPolarHBondContact O-CD2 3.35Å; V226-F230 PolarHBondContact O-N 3.11Å; F230-V233 PolarHBondContact O-N 3.37Å; F230-G234 PolarHBondContact O-N 3.35Å
231	G	96.6	Very high	95	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-60.5	-44.4	174.1	0	0	0	0	0	112.6	F227 L229 V233 G234 V235	F227-G231 PolarHBondContact O-N 3.45Å; L229-G231 PolarHBondContact O-N 3.38Å; G231-V233 PolarHBondContact O-N 3.22Å; G231-G234 PolarHBondContact O-N 3.42Å; G231-G234 VanDerWaalsContact O-N 3.16Å; G231-V235 PolarHBondContact O-N 3.11Å; G231-V235 VanDerWaalsContact O-N 3.09Å
232	A	97.3	Very high	95.4	Very high	48 Å²	48	36.5 Å²	36.5	40%	0.397	20%	0.197	S	C	.	.	H	α-helix	trans	-63.2	-42.5	177.2	0	0	0	0	0	112.4	Y228 L229 G234 V235 V236	Y228-A232 VanDerWaalsContact O-CB 3.27Å; Y228-A232 WeakPolarHBondContact O-CB 3.33Å; Y228-A232 PolarHBondContact O-N 3.27Å; L229-A232 PolarHBondContact O-N 2.98Å; A232-G234 VanDerWaalsContact C-N 3.26Å; A232-G234 PolarHBondContact O-N 2.99Å; A232-V235 PolarHBondContact O-N 3.48Å; A232-V236 WeakPolarHBondContact O-CG2 3.22Å; A232-V236 PolarHBondContact O-N 3.46Å
233	V	96.9	Very high	95.8	Very high	55 Å²	55	43.8 Å²	43.8	33%	0.333	23%	0.228	S	C	.	.	H	α-helix	trans	-59.1	-39.4	174.1	174.3	0	0	0	0	110.9	V49 L229 F230 G231 V236 W237	V49-V233 HydrophobicContact CG2-CG1 3.96Å; L229-V233 WeakPolarHBondContact O-CG2 3.46Å; L229-V233 PolarHBondContact O-N 2.68Å; L229-V233 VanDerWaalsContact O-N 3.08Å; F230-V233 PolarHBondContact O-N 3.37Å; G231-V233 PolarHBondContact O-N 3.22Å; V233-V236 PolarHBondContact O-N 3.13Å; V233-W237 WeakPolarHBondContact O-CB 3.36Å; V233-W237 PolarHBondContact O-N 3.24Å
234	G	96.9	Very high	95.8	Very high	0 Å²	0	47.1 Å²	47.1	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-64.7	-38.9	176.5	0	0	0	0	0	114.2	F230 G231 A232 W237 F238	F230-G234 PolarHBondContact O-N 3.35Å; G231-G234 PolarHBondContact O-N 3.42Å; G231-G234 VanDerWaalsContact O-N 3.16Å; A232-G234 VanDerWaalsContact C-N 3.26Å; A232-G234 PolarHBondContact O-N 2.99Å; G234-W237 PolarHBondContact O-N 2.93Å; G234-F238 PolarHBondContact O-N 2.92Å
235	V	97.9	Very high	95.8	Very high	45 Å²	45	46.2 Å²	46.2	27%	0.273	24%	0.239	S	C	.	.	H	α-helix	trans	-65.6	-44.8	174.8	176.4	0	0	0	0	111	L141 A144 L145 L148 G231 A232 W237 F238 V239	L141-V235 HydrophobicContact CD1-CG1 4.49Å; L141-V235 HydrophobicContact CD1-CG2 4.25Å; A144-V235 HydrophobicContact CB-CG2 4.24Å; L145-V235 HydrophobicContact CD2-CG2 4.22Å; L148-V235 HydrophobicContact CD1-CG2 4.36Å; G231-V235 PolarHBondContact O-N 3.11Å; G231-V235 VanDerWaalsContact O-N 3.09Å; A232-V235 PolarHBondContact O-N 3.48Å; V235-W237 VanDerWaalsContact C-N 3.3Å; V235-W237 PolarHBondContact O-N 2.88Å; V235-F238 WeakPolarHBondContact O-CB 3.16Å; V235-F238 PolarHBondContact O-N 3.34Å; V235-V239 WeakPolarHBondContact O-CG2 3.46Å; V235-V239 PolarHBondContact O-N 3.2Å
236	V	97.4	Very high	95.8	Very high	82 Å²	82	43 Å²	43	50%	0.497	23%	0.228	S	C	.	.	H	α-helix	trans	-60.9	-42.3	176.1	173.6	0	0	0	0	110.9	A232 V233 F238 V239 L240	A232-V236 WeakPolarHBondContact O-CG2 3.22Å; A232-V236 PolarHBondContact O-N 3.46Å; V233-V236 PolarHBondContact O-N 3.13Å; V236-F238 VanDerWaalsContact C-N 3.33Å; V236-F238 PolarHBondContact O-N 2.93Å; V236-V239 WeakPolarHBondContact O-CB 3.16Å; V236-V239 PolarHBondContact O-N 3.2Å; V236-L240 HydrophobicContact CG1-CD1 4.4Å; V236-L240 PolarHBondContact O-N 2.91Å; V236-L240 VanDerWaalsContact O-N 3.1Å
237	W	97.3	Very high	95.4	Very high	0 Å²	0	45.5 Å²	45.5	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-58.3	-44.3	175.1	177.3	91.2	0	0	0	112.1	L42 Y45 G46 V49 M136 V140 V233 G234 V235 V239 L240 W241	L42-W237 PolarHBondContact O-NE1 3.46Å; Y45-W237 AromaticContact CD1-CD1 3.36Å; Y45-W237 HydrophobicContact CD1-CG 4.49Å; Y45-W237 HydrophobicContact CE1-CB 4.37Å; Y45-W237 AromaticContact CE1-CD1 3.61Å; Y45-W237 HydrophobicContact CE1-CG 4.41Å; Y45-W237 AromaticContact CG-CD1 3.85Å; G46-W237 VanDerWaalsContact CA-CZ2 3.42Å; V49-W237 HydrophobicContact CG2-CB 4.05Å; V49-W237 HydrophobicContact CG2-CG 4.15Å; M136-W237 HydrophobicContact CE-CH2 3.92Å; M136-W237 HydrophobicContact CE-CZ2 3.97Å; M136-W237 HydrophobicContact CG-CH2 4.31Å; V140-W237 HydrophobicContact CB-CE3 3.97Å; V140-W237 HydrophobicContact CB-CH2 4.41Å; V140-W237 HydrophobicContact CB-CZ3 3.56Å; V140-W237 HydrophobicContact CG1-CD2 4.46Å; V140-W237 HydrophobicContact CG1-CE3 3.55Å; V140-W237 HydrophobicContact CG1-CZ3 3.7Å; V140-W237 HydrophobicContact CG2-CE3 4.4Å; V140-W237 HydrophobicContact CG2-CH2 4.08Å; V140-W237 HydrophobicContact CG2-CZ3 3.71Å; V233-W237 WeakPolarHBondContact O-CB 3.36Å; V233-W237 PolarHBondContact O-N 3.24Å; G234-W237 PolarHBondContact O-N 2.93Å; V235-W237 VanDerWaalsContact C-N 3.3Å; V235-W237 PolarHBondContact O-N 2.88Å; W237-V239 VanDerWaalsContact C-N 3.3Å; W237-V239 PolarHBondContact O-N 2.89Å; W237-L240 PolarHBondContact O-N 3.08Å; W237-L240 VanDerWaalsContact O-N 3.16Å; W237-W241 HydrophobicContact CD2-CB 4.35Å; W237-W241 HydrophobicContact CE3-CB 4.25Å; W237-W241 HydrophobicContact CH2-CB 3.88Å; W237-W241 AromaticContact CH2-CD2 3.56Å; W237-W241 HydrophobicContact CH2-CD2 3.56Å; W237-W241 AromaticContact CH2-CE3 3.8Å; W237-W241 HydrophobicContact CH2-CE3 3.8Å; W237-W241 AromaticContact CH2-CG 3.59Å; W237-W241 HydrophobicContact CH2-CG 3.59Å; W237-W241 HydrophobicContact CZ2-CB 4Å; W237-W241 AromaticContact CZ2-CD2 3.61Å; W237-W241 HydrophobicContact CZ2-CD2 3.61Å; W237-W241 AromaticContact CZ2-CE3 3.33Å; W237-W241 HydrophobicContact CZ2-CE3 3.33Å; W237-W241 AromaticContact CZ2-CG 3.91Å; W237-W241 HydrophobicContact CZ2-CG 3.91Å; W237-W241 AromaticContact CZ2-CZ3 3.99Å; W237-W241 HydrophobicContact CZ2-CZ3 3.99Å; W237-W241 HydrophobicContact CZ3-CB 3.99Å; W237-W241 HydrophobicContact CZ3-CD2 4.46Å; W237-W241 HydrophobicContact CZ3-CG 4.04Å; W237-W241 WeakPolarHBondContact O-CB 3.37Å; W237-W241 PolarHBondContact O-N 2.92Å
238	F	97.4	Very high	95	Very high	29 Å²	29	47.5 Å²	47.5	13%	0.127	26%	0.255	C	S	.	.	H	α-helix	trans	-59	-42.5	178	169.8	-101.7	0	0	0	111.9	W134 G137 F138 L141 G234 V235 V236 L240 W241 A242	W134-F238 HydrophobicContact CZ3-CZ 4.38Å; G137-F238 VanDerWaalsContact C-CD2 3.49Å; G137-F238 WeakPolarHBondContact O-CD2 3.48Å; F138-F238 HydrophobicContact CD1-CE2 4.01Å; F138-F238 AromaticContact CD1-CZ 3.99Å; F138-F238 HydrophobicContact CD1-CZ 3.99Å; F138-F238 HydrophobicContact CE1-CE2 4.19Å; F138-F238 AromaticContact CE1-CZ 3.78Å; F138-F238 HydrophobicContact CE1-CZ 3.78Å; L141-F238 HydrophobicContact CB-CB 4.21Å; L141-F238 HydrophobicContact CB-CD1 4.36Å; L141-F238 HydrophobicContact CB-CD2 3.89Å; L141-F238 HydrophobicContact CB-CE2 4.34Å; L141-F238 HydrophobicContact CB-CG 3.88Å; L141-F238 HydrophobicContact CD1-CB 4.23Å; L141-F238 HydrophobicContact CD1-CD1 3.98Å; L141-F238 HydrophobicContact CD1-CG 4.12Å; L141-F238 HydrophobicContact CD2-CD1 3.86Å; L141-F238 HydrophobicContact CD2-CD2 4.43Å; L141-F238 HydrophobicContact CD2-CE1 3.72Å; L141-F238 HydrophobicContact CD2-CE2 4.29Å; L141-F238 HydrophobicContact CD2-CG 4.21Å; L141-F238 HydrophobicContact CD2-CZ 3.94Å; L141-F238 HydrophobicContact CG-CD1 4.29Å; L141-F238 HydrophobicContact CG-CG 4.29Å; G234-F238 PolarHBondContact O-N 2.92Å; V235-F238 WeakPolarHBondContact O-CB 3.16Å; V235-F238 PolarHBondContact O-N 3.34Å; V236-F238 VanDerWaalsContact C-N 3.33Å; V236-F238 PolarHBondContact O-N 2.93Å; F238-L240 PolarHBondContact O-N 2.94Å; F238-W241 PolarHBondContact O-N 3.49Å; F238-A242 WeakPolarHBondContact O-CB 3.4Å; F238-A242 PolarHBondContact O-N 3.35Å
239	V	96.8	Very high	94.5	Very high	69 Å²	69	43 Å²	43	42%	0.418	24%	0.238	S	C	.	.	H	α-helix	trans	-59.2	-48.2	176.4	177.1	0	0	0	0	110.2	V235 V236 W237 W241 A242 F243	V235-V239 WeakPolarHBondContact O-CG2 3.46Å; V235-V239 PolarHBondContact O-N 3.2Å; V236-V239 WeakPolarHBondContact O-CB 3.16Å; V236-V239 PolarHBondContact O-N 3.2Å; W237-V239 VanDerWaalsContact C-N 3.3Å; W237-V239 PolarHBondContact O-N 2.89Å; V239-W241 PolarHBondContact O-N 3.39Å; V239-A242 PolarHBondContact O-N 3.11Å; V239-F243 HydrophobicContact CG1-CD2 3.96Å; V239-F243 HydrophobicContact CG1-CE2 3.78Å; V239-F243 WeakPolarHBondContact O-CD2 3.49Å; V239-F243 PolarHBondContact O-N 3.2Å
240	L	95.6	Very high	94	Very high	71 Å²	71	44.1 Å²	44.1	37%	0.372	25%	0.245	S	C	.	.	H	α-helix	trans	-61.3	-44.2	176.9	-65.9	174.6	0	0	0	112.1	Y45 V236 W237 F238 A242 F243 L244	Y45-L240 HydrophobicContact CE1-CD1 4.31Å; V236-L240 HydrophobicContact CG1-CD1 4.4Å; V236-L240 PolarHBondContact O-N 2.91Å; V236-L240 VanDerWaalsContact O-N 3.1Å; W237-L240 PolarHBondContact O-N 3.08Å; W237-L240 VanDerWaalsContact O-N 3.16Å; F238-L240 PolarHBondContact O-N 2.94Å; L240-A242 PolarHBondContact O-N 2.77Å; L240-F243 PolarHBondContact O-N 2.97Å; L240-L244 HydrophobicContact CB-CD1 4.39Å; L240-L244 HydrophobicContact CD2-CD1 4.5Å; L240-L244 VanDerWaalsContact O-CB 3.27Å; L240-L244 WeakPolarHBondContact O-CB 3.34Å; L240-L244 VanDerWaalsContact O-CG 3.28Å; L240-L244 WeakPolarHBondContact O-CG 3.16Å; L240-L244 PolarHBondContact O-N 3.5Å
241	W	96	Very high	93.6	Very high	2 Å²	2	46.3 Å²	46.3	1%	0.008	26%	0.262	C	S	.	.	H	α-helix	trans	-61.5	-43.9	178.5	-179.1	-98.5	0	0	0	112.3	L39 L42 K133 M136 M179 W237 F238 V239 F243 V245	L39-W241 HydrophobicContact CD1-CH2 4.2Å; L39-W241 HydrophobicContact CD1-CZ3 4.43Å; L42-W241 HydrophobicContact CB-CZ3 4.47Å; K133-W241 PolarHBondContact O-NE1 3.01Å; M136-W241 HydrophobicContact CB-CZ2 4.4Å; M136-W241 HydrophobicContact CE-CH2 4.33Å; M136-W241 HydrophobicContact CG-CZ2 4.37Å; M136-W241 HydrophobicContact SD-CH2 3.73Å; M136-W241 HydrophobicContact SD-CZ2 3.68Å; M136-W241 HydrophobicContact SD-CZ3 4.47Å; M179-W241 HydrophobicContact SD-CH2 4.31Å; W237-W241 HydrophobicContact CD2-CB 4.35Å; W237-W241 HydrophobicContact CE3-CB 4.25Å; W237-W241 HydrophobicContact CH2-CB 3.88Å; W237-W241 AromaticContact CH2-CD2 3.56Å; W237-W241 HydrophobicContact CH2-CD2 3.56Å; W237-W241 AromaticContact CH2-CE3 3.8Å; W237-W241 HydrophobicContact CH2-CE3 3.8Å; W237-W241 AromaticContact CH2-CG 3.59Å; W237-W241 HydrophobicContact CH2-CG 3.59Å; W237-W241 HydrophobicContact CZ2-CB 4Å; W237-W241 AromaticContact CZ2-CD2 3.61Å; W237-W241 HydrophobicContact CZ2-CD2 3.61Å; W237-W241 AromaticContact CZ2-CE3 3.33Å; W237-W241 HydrophobicContact CZ2-CE3 3.33Å; W237-W241 AromaticContact CZ2-CG 3.91Å; W237-W241 HydrophobicContact CZ2-CG 3.91Å; W237-W241 AromaticContact CZ2-CZ3 3.99Å; W237-W241 HydrophobicContact CZ2-CZ3 3.99Å; W237-W241 HydrophobicContact CZ3-CB 3.99Å; W237-W241 HydrophobicContact CZ3-CD2 4.46Å; W237-W241 HydrophobicContact CZ3-CG 4.04Å; W237-W241 WeakPolarHBondContact O-CB 3.37Å; W237-W241 PolarHBondContact O-N 2.92Å; F238-W241 PolarHBondContact O-N 3.49Å; V239-W241 PolarHBondContact O-N 3.39Å; W241-F243 VanDerWaalsContact C-N 3.29Å; W241-F243 PolarHBondContact O-N 2.9Å; W241-V245 HydrophobicContact CD2-CB 4.04Å; W241-V245 HydrophobicContact CD2-CG1 4.4Å; W241-V245 HydrophobicContact CD2-CG2 3.84Å; W241-V245 HydrophobicContact CE3-CB 4.15Å; W241-V245 HydrophobicContact CE3-CG1 4.49Å; W241-V245 HydrophobicContact CE3-CG2 3.45Å; W241-V245 VanDerWaalsContact CE3-CG2 3.45Å; W241-V245 HydrophobicContact CH2-CB 4.37Å; W241-V245 HydrophobicContact CH2-CG1 3.83Å; W241-V245 HydrophobicContact CH2-CG2 4.08Å; W241-V245 HydrophobicContact CZ2-CB 4.27Å; W241-V245 HydrophobicContact CZ2-CG1 3.71Å; W241-V245 HydrophobicContact CZ2-CG2 4.42Å; W241-V245 HydrophobicContact CZ3-CB 4.32Å; W241-V245 HydrophobicContact CZ3-CG1 4.24Å; W241-V245 HydrophobicContact CZ3-CG2 3.59Å; W241-V245 PolarHBondContact O-N 3.35Å; W241-V245 VanDerWaalsContact O-N 3.15Å
242	A	95	Very high	93.3	Very high	18 Å²	18	47.7 Å²	47.7	15%	0.149	27%	0.268	C	S	.	.	H	α-helix	trans	-60.5	-38.2	180	0	0	0	0	0	112.2	K133 W134 F238 V239 L240	K133-A242 WeakPolarHBondContact CE-O 3.39Å; K133-A242 PolarHBondContact NZ-O 3.39Å; W134-A242 HydrophobicContact CH2-CB 4.21Å; W134-A242 HydrophobicContact CZ3-CB 4.14Å; F238-A242 WeakPolarHBondContact O-CB 3.4Å; F238-A242 PolarHBondContact O-N 3.35Å; V239-A242 PolarHBondContact O-N 3.11Å; L240-A242 PolarHBondContact O-N 2.77Å
243	F	93.4	Very high	92.8	Very high	157 Å²	157	50 Å²	50	69%	0.689	28%	0.279	S	S	*	.	H	α-helix	trans	-87.2	-31.8	-178.9	-70.9	-63.3	0	0	0	114.6	V239 L240 W241	V239-F243 HydrophobicContact CG1-CD2 3.96Å; V239-F243 HydrophobicContact CG1-CE2 3.78Å; V239-F243 WeakPolarHBondContact O-CD2 3.49Å; V239-F243 PolarHBondContact O-N 3.2Å; L240-F243 PolarHBondContact O-N 2.97Å; W241-F243 VanDerWaalsContact C-N 3.29Å; W241-F243 PolarHBondContact O-N 2.9Å
244	L	92.4	Very high	92.3	Very high	74 Å²	74	57.2 Å²	57.2	39%	0.387	30%	0.3	S	S	.	.	H	α-helix	trans	-99	-23.8	-169.2	-62.1	175.8	0	0	0	114.6	L42 L240	L42-L244 HydrophobicContact CD1-CB 3.7Å; L42-L244 HydrophobicContact CD1-CD1 4.19Å; L42-L244 HydrophobicContact CD2-CD1 4Å; L240-L244 HydrophobicContact CB-CD1 4.39Å; L240-L244 HydrophobicContact CD2-CD1 4.5Å; L240-L244 VanDerWaalsContact O-CB 3.27Å; L240-L244 WeakPolarHBondContact O-CB 3.34Å; L240-L244 VanDerWaalsContact O-CG 3.28Å; L240-L244 WeakPolarHBondContact O-CG 3.16Å; L240-L244 PolarHBondContact O-N 3.5Å
245	V	93.8	Very high	92	Very high	3 Å²	3	58.3 Å²	58.3	2%	0.018	31%	0.306	C	S	.	.			trans	-102.4	148.9	-174.5	175.9	0	0	0	0	112.1	L39 L42 K133 M182 W241	L39-V245 HydrophobicContact CD1-CB 4.45Å; L39-V245 HydrophobicContact CD1-CG1 3.63Å; L39-V245 HydrophobicContact CD1-CG2 4.01Å; L42-V245 HydrophobicContact CB-CG2 4.34Å; L42-V245 HydrophobicContact CD1-CG2 3.9Å; K133-V245 WeakPolarHBondContact CD-O 3.37Å; K133-V245 WeakPolarHBondContact CE-O 3.35Å; K133-V245 HydrophobicContact CG-CG1 4.24Å; K133-V245 PolarHBondContact NZ-O 3.29Å; M182-V245 HydrophobicContact CE-CG1 4.32Å; W241-V245 HydrophobicContact CD2-CB 4.04Å; W241-V245 HydrophobicContact CD2-CG1 4.4Å; W241-V245 HydrophobicContact CD2-CG2 3.84Å; W241-V245 HydrophobicContact CE3-CB 4.15Å; W241-V245 HydrophobicContact CE3-CG1 4.49Å; W241-V245 HydrophobicContact CE3-CG2 3.45Å; W241-V245 VanDerWaalsContact CE3-CG2 3.45Å; W241-V245 HydrophobicContact CH2-CB 4.37Å; W241-V245 HydrophobicContact CH2-CG1 3.83Å; W241-V245 HydrophobicContact CH2-CG2 4.08Å; W241-V245 HydrophobicContact CZ2-CB 4.27Å; W241-V245 HydrophobicContact CZ2-CG1 3.71Å; W241-V245 HydrophobicContact CZ2-CG2 4.42Å; W241-V245 HydrophobicContact CZ3-CB 4.32Å; W241-V245 HydrophobicContact CZ3-CG1 4.24Å; W241-V245 HydrophobicContact CZ3-CG2 3.59Å; W241-V245 PolarHBondContact O-N 3.35Å; W241-V245 VanDerWaalsContact O-N 3.15Å
246	F	91.9	Very high	91.6	Very high	52 Å²	52	58.7 Å²	58.7	23%	0.228	31%	0.31	C	S	.	.			trans	-135.7	143.4	-179.7	-62.3	-91.9	0	0	0	110.4	W186 S248 H252 P253	W186-F246 WeakPolarHBondContact CZ2-O 3.26Å; W186-F246 PolarHBondContact NE1-O 3.31Å; F246-S248 VanDerWaalsContact C-N 3.34Å; F246-S248 PolarHBondContact O-N 3.47Å; F246-H252 HydrophobicContact CB-CB 4.24Å; F246-H252 HydrophobicContact CD2-CB 4.43Å; F246-H252 AromaticContact CD2-CD2 3.33Å; F246-H252 WeakPolarHBondContact CD2-CD2 3.33Å; F246-H252 AromaticContact CD2-CG 3.95Å; F246-H252 AromaticContact CD2-NE2 3.91Å; F246-H252 HydrophobicContact CG-CB 4.38Å; F246-P253 HydrophobicContact CE1-CG 4.05Å; F246-P253 HydrophobicContact CE2-CG 4.17Å; F246-P253 VanDerWaalsContact CZ-CD 3.4Å; F246-P253 HydrophobicContact CZ-CG 3.67Å
247	D	87.1	Confident	91.1	Very high	52 Å²	52	60.9 Å²	60.9	28%	0.278	32%	0.315	S	S	.	.	S	Bend	trans	-65.2	-33.6	-173.7	-82.3	-54.1	0	0	0	113.7	A132 K133 W186	A132-D247 PolarHBondContact N-OD1 2.81Å; K133-D247 WeakPolarHBondContact CB-OD1 3.22Å; K133-D247 PolarHBondContact N-OD1 3.47Å; W186-D247 PolarHBondContact NE1-O 3.34Å
248	S	86.1	Confident	90.5	Very high	41 Å²	41	67.2 Å²	67.2	29%	0.287	35%	0.345	S	S	.	.	S	Bend	trans	-134.4	152.7	-179.7	73.1	0	0	0	0	112.3	F246 N250 S251 H252	F246-S248 VanDerWaalsContact C-N 3.34Å; F246-S248 PolarHBondContact O-N 3.47Å; S248-N250 PolarHBondContact O-N 3.21Å; S248-S251 PolarHBondContact N-OG 2.88Å; S248-S251 VanDerWaalsContact N-OG 3.12Å; S248-S251 PolarHBondContact O-N 2.82Å; S248-S251 VanDerWaalsContact O-N 3.1Å; S248-S251 PolarHBondContact O-OG 3.26Å; S248-S251 WeakPolarHBondContact OG-CB 2.89Å; S248-S251 PolarHBondContact OG-N 2.81Å; S248-S251 VanDerWaalsContact OG-N 3.16Å; S248-S251 PolarHBondContact OG-OG 2.97Å; S248-H252 PolarHBondContact O-N 2.8Å
249	P	86.9	Confident	90.1	Very high	8 Å²	8	66 Å²	66	5%	0.052	34%	0.34	C	S	.	.	G	3₁₀ helix	trans	-55.1	-32.7	171.6	-24.2	32.6	0	0	0	112.6	W186 H252 I255 I263	W186-P249 HydrophobicContact CD2-CG 3.98Å; W186-P249 HydrophobicContact CE3-CG 4.17Å; W186-P249 HydrophobicContact CG-CG 4.38Å; W186-P249 HydrophobicContact CZ2-CG 4.47Å; W186-P249 HydrophobicContact CZ3-CG 4.5Å; P249-H252 PolarHBondContact O-N 3.48Å; P249-I255 HydrophobicContact CB-CD1 3.93Å; P249-I263 HydrophobicContact CB-CD1 4.38Å; P249-I263 HydrophobicContact CG-CB 4.45Å; P249-I263 HydrophobicContact CG-CD1 4.2Å; P249-I263 HydrophobicContact CG-CG2 3.81Å
250	N	85.6	Confident	89.7	Confident	107 Å²	107	66.9 Å²	66.9	57%	0.572	34%	0.336	S	S	*	.	G	3₁₀ helix	trans	-71.5	-30.8	-179.8	-67.2	-32	0	0	0	113.3	S248 H252	S248-N250 PolarHBondContact O-N 3.21Å; N250-H252 VanDerWaalsContact C-N 3.32Å
251	S	87.4	Confident	89.3	Confident	60 Å²	60	67.3 Å²	67.3	42%	0.42	34%	0.338	S	S	.	.	G	3₁₀ helix	trans	-81.9	-10.1	176.3	57	0	0	0	0	113.8	S248 P253	S248-S251 PolarHBondContact N-OG 2.88Å; S248-S251 VanDerWaalsContact N-OG 3.12Å; S248-S251 PolarHBondContact O-N 2.82Å; S248-S251 VanDerWaalsContact O-N 3.1Å; S248-S251 PolarHBondContact O-OG 3.26Å; S248-S251 WeakPolarHBondContact OG-CB 2.89Å; S248-S251 PolarHBondContact OG-N 2.81Å; S248-S251 VanDerWaalsContact OG-N 3.16Å; S248-S251 PolarHBondContact OG-OG 2.97Å; S251-P253 WeakPolarHBondContact O-CD 3.43Å
252	H	89.1	Confident	88.8	Confident	29 Å²	29	67.8 Å²	67.8	13%	0.134	34%	0.34	C	S	.	.			trans	-80.1	116	-173.3	-170.4	-74.9	0	0	0	111	W186 F246 S248 P249 N250 R254 I255	W186-H252 HydrophobicContact CH2-CB 3.94Å; W186-H252 AromaticContact CH2-CD2 3.59Å; W186-H252 AromaticContact CH2-CG 3.96Å; W186-H252 HydrophobicContact CZ2-CB 4.31Å; F246-H252 HydrophobicContact CB-CB 4.24Å; F246-H252 HydrophobicContact CD2-CB 4.43Å; F246-H252 AromaticContact CD2-CD2 3.33Å; F246-H252 WeakPolarHBondContact CD2-CD2 3.33Å; F246-H252 AromaticContact CD2-CG 3.95Å; F246-H252 AromaticContact CD2-NE2 3.91Å; F246-H252 HydrophobicContact CG-CB 4.38Å; S248-H252 PolarHBondContact O-N 2.8Å; P249-H252 PolarHBondContact O-N 3.48Å; N250-H252 VanDerWaalsContact C-N 3.32Å; H252-R254 VanDerWaalsContact C-N 3.33Å; H252-R254 PolarHBondContact ND1-N 2.98Å; H252-R254 PolarHBondContact O-N 3.25Å; H252-I255 HydrophobicContact CB-CB 4.08Å; H252-I255 HydrophobicContact CB-CG2 4.17Å; H252-I255 PolarHBondContact ND1-N 3.3Å; H252-I255 WeakPolarHBondContact O-CG2 3.44Å
253	P	87.7	Confident	88.5	Confident	95 Å²	95	67 Å²	67	62%	0.617	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73	-23.2	-170.8	27.6	-34.4	0	0	0	113.9	F246 S251	F246-P253 HydrophobicContact CE1-CG 4.05Å; F246-P253 HydrophobicContact CE2-CG 4.17Å; F246-P253 VanDerWaalsContact CZ-CD 3.4Å; F246-P253 HydrophobicContact CZ-CG 3.67Å; S251-P253 WeakPolarHBondContact O-CD 3.43Å
254	R	86.7	Confident	88.1	Confident	207 Å²	207	62.1 Å²	62.1	78%	0.781	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.5	9.6	-174.5	-61.3	178.4	-175.8	164.5	0.8	114	H252	H252-R254 VanDerWaalsContact C-N 3.33Å; H252-R254 PolarHBondContact ND1-N 2.98Å; H252-R254 PolarHBondContact O-N 3.25Å
255	I	90.7	Very high	87.8	Confident	24 Å²	24	62.5 Å²	62.5	12%	0.123	32%	0.319	C	S	.	.			trans	-77.3	139.6	-177.4	-165	169.9	0	0	0	109.3	W186 P249 H252 E259 R260 I263	W186-I255 HydrophobicContact CH2-CD1 4.38Å; W186-I255 HydrophobicContact CZ3-CD1 4.14Å; P249-I255 HydrophobicContact CB-CD1 3.93Å; H252-I255 HydrophobicContact CB-CB 4.08Å; H252-I255 HydrophobicContact CB-CG2 4.17Å; H252-I255 PolarHBondContact ND1-N 3.3Å; H252-I255 WeakPolarHBondContact O-CG2 3.44Å; I255-E259 HydrophobicContact CD1-CB 4.49Å; I255-E259 HydrophobicContact CD1-CG 4.21Å; I255-E259 HydrophobicContact CG1-CB 4.14Å; I255-E259 HydrophobicContact CG1-CG 4.24Å; I255-R260 HydrophobicContact CD1-CB 4.25Å; I255-R260 HydrophobicContact CG2-CB 4.18Å; I255-I263 HydrophobicContact CD1-CD1 4.35Å
256	S	88.9	Confident	87.2	Confident	52 Å²	52	63.6 Å²	63.6	36%	0.364	33%	0.326	S	S	.	.			trans	-67.8	143.4	172.1	70.5	0	0	0	0	110.3	Q258 E259 R260	S256-Q258 PolarHBondContact O-N 3.17Å; S256-E259 PolarHBondContact O-N 3.27Å; S256-E259 VanDerWaalsContact O-N 3.14Å; S256-E259 WeakPolarHBondContact OG-CB 3.35Å; S256-E259 PolarHBondContact OG-N 3.4Å; S256-R260 PolarHBondContact O-N 2.95Å
257	E	87	Confident	86.7	Confident	128 Å²	128	61.2 Å²	61.2	60%	0.598	32%	0.316	S	S	*	.	H	α-helix	trans	-61.5	-36.1	178.9	-176.3	167.4	-150.3	0	0	111.9	E259 R260 L261	E257-E259 PolarHBondContact O-N 3.18Å; E257-R260 PolarHBondContact O-N 3.49Å; E257-R260 IonicContact OE1-NH2 2.86Å; E257-R260 PolarHBondContact OE1-NH2 2.8Å; E257-L261 HydrophobicContact CG-CD1 3.99Å; E257-L261 HydrophobicContact CG-CG 4.33Å; E257-L261 WeakPolarHBondContact O-CB 3.15Å; E257-L261 WeakPolarHBondContact O-CG 3.44Å; E257-L261 PolarHBondContact O-N 2.97Å
258	Q	85.9	Confident	85.9	Confident	133 Å²	133	66.1 Å²	66.1	62%	0.621	34%	0.335	S	S	*	.	H	α-helix	trans	-58.8	-45.8	174	-66.7	178.7	-4.7	0	0	112	S256 Y262	S256-Q258 PolarHBondContact O-N 3.17Å; Q258-Y262 VanDerWaalsContact O-CB 3.3Å; Q258-Y262 WeakPolarHBondContact O-CB 3.44Å; Q258-Y262 PolarHBondContact O-N 3.1Å
259	E	87.6	Confident	84.7	Confident	4 Å²	4	70.6 Å²	70.6	2%	0.019	36%	0.356	C	S	.	.	H	α-helix	trans	-69	-41.1	178.1	-175	175.3	-168.3	0	0	111.9	A29 S34 S35 R36 I255 S256 E257 L261 Y262 I263	A29-E259 HydrophobicContact CB-CB 4.08Å; A29-E259 HydrophobicContact CB-CG 4.36Å; S34-E259 PolarHBondContact OG-OE1 2.95Å; S35-E259 PolarHBondContact N-OE1 3.35Å; S35-E259 VanDerWaalsContact N-OE1 3.09Å; S35-E259 PolarHBondContact N-OE2 2.99Å; R36-E259 PolarHBondContact N-OE1 3.16Å; I255-E259 HydrophobicContact CD1-CB 4.49Å; I255-E259 HydrophobicContact CD1-CG 4.21Å; I255-E259 HydrophobicContact CG1-CB 4.14Å; I255-E259 HydrophobicContact CG1-CG 4.24Å; S256-E259 PolarHBondContact O-N 3.27Å; S256-E259 VanDerWaalsContact O-N 3.14Å; S256-E259 WeakPolarHBondContact OG-CB 3.35Å; S256-E259 PolarHBondContact OG-N 3.4Å; E257-E259 PolarHBondContact O-N 3.18Å; E259-L261 PolarHBondContact O-N 3.19Å; E259-Y262 WeakPolarHBondContact O-CB 3.45Å; E259-Y262 PolarHBondContact O-N 3.17Å; E259-I263 HydrophobicContact CG-CD1 3.99Å; E259-I263 WeakPolarHBondContact O-CG1 3.5Å; E259-I263 PolarHBondContact O-N 3.18Å
260	R	87.8	Confident	83.6	Confident	88 Å²	88	72.5 Å²	72.5	33%	0.332	36%	0.364	S	S	.	.	H	α-helix	trans	-58.5	-48.5	175.9	-174	-176.6	69.5	169.6	-1.1	111.3	I255 S256 E257 I263 T264	I255-R260 HydrophobicContact CD1-CB 4.25Å; I255-R260 HydrophobicContact CG2-CB 4.18Å; S256-R260 PolarHBondContact O-N 2.95Å; E257-R260 PolarHBondContact O-N 3.49Å; E257-R260 IonicContact OE1-NH2 2.86Å; E257-R260 PolarHBondContact OE1-NH2 2.8Å; R260-I263 PolarHBondContact O-N 3.12Å; R260-T264 WeakPolarHBondContact O-CB 3.45Å; R260-T264 PolarHBondContact O-N 3.11Å; R260-T264 PolarHBondContact O-OG1 3.36Å
261	L	87.4	Confident	82.3	Confident	79 Å²	79	71.1 Å²	71.1	41%	0.414	36%	0.356	S	S	.	.	H	α-helix	trans	-65.5	-41.5	178.3	-71.5	172.3	0	0	0	111.6	E257 E259 I263 T264 N265	E257-L261 HydrophobicContact CG-CD1 3.99Å; E257-L261 HydrophobicContact CG-CG 4.33Å; E257-L261 WeakPolarHBondContact O-CB 3.15Å; E257-L261 WeakPolarHBondContact O-CG 3.44Å; E257-L261 PolarHBondContact O-N 2.97Å; E259-L261 PolarHBondContact O-N 3.19Å; L261-I263 PolarHBondContact O-N 2.92Å; L261-T264 PolarHBondContact O-N 3.48Å; L261-N265 WeakPolarHBondContact O-CB 3.36Å; L261-N265 VanDerWaalsContact O-CG 3.25Å; L261-N265 PolarHBondContact O-N 2.91Å; L261-N265 PolarHBondContact O-ND2 3.19Å
262	Y	86.8	Confident	80.5	Confident	12 Å²	12	71.4 Å²	71.4	5%	0.047	36%	0.358	C	S	.	.	H	α-helix	trans	-55.5	-49.8	175.4	173.9	-113.8	0	0	0	112.1	I26 Q27 R28 A29 P188 Q258 E259 S266	I26-Y262 HydrophobicContact CG2-CD2 3.35Å; I26-Y262 HydrophobicContact CG2-CE2 3.59Å; Q27-Y262 VanDerWaalsContact O-CD2 3.3Å; Q27-Y262 WeakPolarHBondContact O-CD2 3.15Å; R28-Y262 HydrophobicContact CG-CE2 4.46Å; A29-Y262 HydrophobicContact CB-CD1 4.03Å; A29-Y262 HydrophobicContact CB-CG 4.12Å; P188-Y262 HydrophobicContact CB-CE1 4.15Å; P188-Y262 HydrophobicContact CG-CD1 4.15Å; P188-Y262 HydrophobicContact CG-CE1 3.55Å; Q258-Y262 VanDerWaalsContact O-CB 3.3Å; Q258-Y262 WeakPolarHBondContact O-CB 3.44Å; Q258-Y262 PolarHBondContact O-N 3.1Å; E259-Y262 WeakPolarHBondContact O-CB 3.45Å; E259-Y262 PolarHBondContact O-N 3.17Å; Y262-S266 VanDerWaalsContact O-CB 3.23Å; Y262-S266 WeakPolarHBondContact O-CB 3.42Å; Y262-S266 PolarHBondContact O-N 2.88Å; Y262-S266 VanDerWaalsContact O-N 3.08Å; Y262-S266 PolarHBondContact O-OG 2.98Å
263	I	87.6	Confident	78.7	Confident	1 Å²	1	73.9 Å²	73.9	1%	0.005	38%	0.375	C	S	.	.	H	α-helix	trans	-66	-51.1	179.5	-63.8	166.7	0	0	0	110.4	W186 P188 P249 I255 E259 R260 L261 N265 S266 L267	W186-I263 HydrophobicContact CE3-CD1 4.28Å; P188-I263 HydrophobicContact CG-CG1 4.28Å; P249-I263 HydrophobicContact CB-CD1 4.38Å; P249-I263 HydrophobicContact CG-CB 4.45Å; P249-I263 HydrophobicContact CG-CD1 4.2Å; P249-I263 HydrophobicContact CG-CG2 3.81Å; I255-I263 HydrophobicContact CD1-CD1 4.35Å; E259-I263 HydrophobicContact CG-CD1 3.99Å; E259-I263 WeakPolarHBondContact O-CG1 3.5Å; E259-I263 PolarHBondContact O-N 3.18Å; R260-I263 PolarHBondContact O-N 3.12Å; L261-I263 PolarHBondContact O-N 2.92Å; I263-N265 PolarHBondContact O-N 3.48Å; I263-S266 PolarHBondContact O-N 3.04Å; I263-L267 HydrophobicContact CG2-CD1 3.57Å; I263-L267 HydrophobicContact CG2-CG 4.36Å; I263-L267 WeakPolarHBondContact O-CB 3.28Å; I263-L267 WeakPolarHBondContact O-CG 3.37Å; I263-L267 PolarHBondContact O-N 3.23Å
264	T	86.2	Confident	76.7	Confident	56 Å²	56	72.2 Å²	72.2	34%	0.344	37%	0.366	S	S	.	.	H	α-helix	trans	-62.7	-42.9	-174.7	-48.8	0	0	0	0	111.4	R260 L261 L267 K268	R260-T264 WeakPolarHBondContact O-CB 3.45Å; R260-T264 PolarHBondContact O-N 3.11Å; R260-T264 PolarHBondContact O-OG1 3.36Å; L261-T264 PolarHBondContact O-N 3.48Å; T264-L267 PolarHBondContact O-N 2.93Å; T264-K268 PolarHBondContact O-N 3.13Å
265	N	85.3	Confident	75.1	Confident	82 Å²	82	67.8 Å²	67.8	44%	0.439	37%	0.374	S	S	.	.	H	α-helix	trans	-68	-37.5	177	-70.4	-16.7	0	0	0	112.1	L261 I263 L267	L261-N265 WeakPolarHBondContact O-CB 3.36Å; L261-N265 VanDerWaalsContact O-CG 3.25Å; L261-N265 PolarHBondContact O-N 2.91Å; L261-N265 PolarHBondContact O-ND2 3.19Å; I263-N265 PolarHBondContact O-N 3.48Å; N265-L267 VanDerWaalsContact C-N 3.26Å; N265-L267 PolarHBondContact O-N 3.39Å
266	S	81.6	Confident	73.6	Confident	25 Å²	25	69.7 Å²	69.7	18%	0.175	40%	0.399	C	S	.	.	H	α-helix	trans	-67.9	-26.1	177.3	-60.3	0	0	0	0	113.1	Y262 I263	Y262-S266 VanDerWaalsContact O-CB 3.23Å; Y262-S266 WeakPolarHBondContact O-CB 3.42Å; Y262-S266 PolarHBondContact O-N 2.88Å; Y262-S266 VanDerWaalsContact O-N 3.08Å; Y262-S266 PolarHBondContact O-OG 2.98Å; I263-S266 PolarHBondContact O-N 3.04Å
267	L	80.5	Confident	72.8	Confident	2 Å²	2	74.4 Å²	74.4	1%	0.01	42%	0.415	C	S	.	.	H	α-helix	trans	-102.4	-6.8	-177.1	-64.9	175.3	0	0	0	114.2	A185 I263 T264 N265 N269 E270 L271	A185-L267 WeakPolarHBondContact O-CD1 3.41Å; I263-L267 HydrophobicContact CG2-CD1 3.57Å; I263-L267 HydrophobicContact CG2-CG 4.36Å; I263-L267 WeakPolarHBondContact O-CB 3.28Å; I263-L267 WeakPolarHBondContact O-CG 3.37Å; I263-L267 PolarHBondContact O-N 3.23Å; T264-L267 PolarHBondContact O-N 2.93Å; N265-L267 VanDerWaalsContact C-N 3.26Å; N265-L267 PolarHBondContact O-N 3.39Å; L267-N269 PolarHBondContact O-N 3.37Å; L267-E270 PolarHBondContact O-N 3.03Å; L267-L271 HydrophobicContact CB-CD1 3.54Å; L267-L271 HydrophobicContact CB-CG 4Å; L267-L271 HydrophobicContact CD1-CD1 3.85Å; L267-L271 HydrophobicContact CG-CD1 4.27Å; L267-L271 PolarHBondContact O-N 3.46Å
268	K	70.9	Confident	72.6	Confident	155 Å²	155	70 Å²	70	67%	0.674	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.5	-32.4	-175.7	-167.6	176.6	-179.6	-177.6	0	113.8	T264	T264-K268 PolarHBondContact O-N 3.13Å
269	N	61.6	Low	72.6	Confident	136 Å²	136	65.2 Å²	65.2	73%	0.727	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.1	-11.9	179.7	-62.3	-21.3	0	0	0	114.2	L267	L267-N269 PolarHBondContact O-N 3.37Å
270	E	63.3	Low	72.7	Confident	47 Å²	47	70 Å²	70	22%	0.22	39%	0.394	C	S	.	.	T	Hydrogen-bonded Turn	trans	-103	-30.1	-178.9	-68.1	-161.2	174.3	0	0	113.3	P189 R192 L267 P417 S418	P189-E270 WeakPolarHBondContact CG-OE1 3.21Å; R192-E270 IonicContact CZ-OE2 2.88Å; R192-E270 IonicContact NH1-OE1 3.76Å; R192-E270 IonicContact NH1-OE2 3.14Å; R192-E270 PolarHBondContact NH1-OE2 3.3Å; R192-E270 VanDerWaalsContact NH1-OE2 3.16Å; R192-E270 IonicContact NH2-OE2 2.97Å; R192-E270 PolarHBondContact NH2-OE2 3.01Å; L267-E270 PolarHBondContact O-N 3.03Å; E270-P417 WeakPolarHBondContact OE2-CB 3.33Å; E270-P417 WeakPolarHBondContact OE2-CG 3.5Å; E270-S418 PolarHBondContact O-OG 3.02Å
271	L	58	Low	72.7	Confident	78 Å²	78	76 Å²	76	41%	0.408	42%	0.416	S	S	.	.			trans	-87.2	-2.1	-175.5	-76.6	172.1	0	0	0	114.6	L267 T273	L267-L271 HydrophobicContact CB-CD1 3.54Å; L267-L271 HydrophobicContact CB-CG 4Å; L267-L271 HydrophobicContact CD1-CD1 3.85Å; L267-L271 HydrophobicContact CG-CD1 4.27Å; L267-L271 PolarHBondContact O-N 3.46Å; L271-T273 PolarHBondContact O-N 3.39Å; L271-T273 PolarHBondContact O-OG1 2.78Å
272	S	50.6	Low	72.7	Confident	67 Å²	67	73.9 Å²	73.9	47%	0.469	41%	0.411	S	S	.	.			trans	-71	67.1	177.9	46.2	0	0	0	0	111.7
273	T	50.2	Low	72.9	Confident	80 Å²	80	73.3 Å²	73.3	49%	0.491	41%	0.408	S	S	.	.			trans	-72.3	124.3	169.3	31.5	0	0	0	0	108.6	L271 A275	L271-T273 PolarHBondContact O-N 3.39Å; L271-T273 PolarHBondContact O-OG1 2.78Å; T273-A275 PolarHBondContact O-N 3.3Å
274	S	45.6	Very low	73	Confident	61 Å²	61	76.7 Å²	76.7	43%	0.427	43%	0.429	S	S	.	.			trans	-66.2	116.8	160.2	-174.2	0	0	0	0	107.1	G276	S274-G276 PolarHBondContact O-N 3.37Å
275	A	52.5	Low	73.2	Confident	114 Å²	114	78.9 Å²	78.9	94%	0.942	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.9	17.6	179	0	0	0	0	0	114.9	T273	T273-A275 PolarHBondContact O-N 3.3Å
276	G	60	Low	73.5	Confident	64 Å²	64	75.4 Å²	75.4	66%	0.66	42%	0.424	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.6	-47.8	-169	0	0	0	0	0	116.1	S274	S274-G276 PolarHBondContact O-N 3.37Å
277	H	73	Confident	74.1	Confident	151 Å²	151	78.9 Å²	78.9	70%	0.699	44%	0.439	S	S	*	.			trans	-154.4	123.6	-164	-167	72.1	0	0	0	113.5
278	I	81.9	Confident	74.7	Confident	36 Å²	36	79.3 Å²	79.3	19%	0.185	44%	0.442	C	S	.	.			trans	-86.1	122.5	172.5	-61.1	164.1	0	0	0	107.9	Y125 W280 I283 Y419 I422	Y125-I278 HydrophobicContact CD2-CD1 3.99Å; Y125-I278 HydrophobicContact CE2-CD1 3.95Å; I278-W280 HydrophobicContact CD1-CZ2 4.28Å; I278-W280 HydrophobicContact CG2-CD2 4.11Å; I278-W280 HydrophobicContact CG2-CG 4.29Å; I278-W280 HydrophobicContact CG2-CZ2 4.31Å; I278-W280 VanDerWaalsContact O-CD1 3.27Å; I278-W280 PolarHBondContact O-N 2.78Å; I278-I283 HydrophobicContact CG2-CD1 3.82Å; I278-Y419 HydrophobicContact CG1-CE1 4.35Å; I278-Y419 HydrophobicContact CG2-CE1 4.41Å; I278-I422 HydrophobicContact CD1-CD1 3.81Å; I278-I422 HydrophobicContact CG1-CD1 4.44Å; I278-I422 HydrophobicContact CG2-CD1 4.3Å
279	P	87	Confident	75.9	Confident	31 Å²	31	72 Å²	72	20%	0.201	41%	0.41	C	S	.	.			trans	-79.3	65.7	-176.6	33.7	-36.5	0	0	0	111.8	R281 A282 I283	P279-R281 VanDerWaalsContact C-N 3.32Å; P279-R281 PolarHBondContact O-N 2.88Å; P279-A282 HydrophobicContact CB-CB 4.19Å; P279-A282 PolarHBondContact O-N 3.36Å; P279-I283 HydrophobicContact CG-CD1 4.26Å; P279-I283 HydrophobicContact CG-CG1 4.35Å; P279-I283 WeakPolarHBondContact O-CG1 3.27Å; P279-I283 PolarHBondContact O-N 3.06Å
280	W	89.2	Confident	77.5	Confident	106 Å²	106	69.3 Å²	69.3	40%	0.402	39%	0.394	S	S	.	.	H	α-helix	trans	-49.3	-48.3	-174.7	-72.5	102.7	0	0	0	113.5	I121 I278 A282 I283 V284 I422 I426	I121-W280 HydrophobicContact CG2-CH2 4.45Å; I278-W280 HydrophobicContact CD1-CZ2 4.28Å; I278-W280 HydrophobicContact CG2-CD2 4.11Å; I278-W280 HydrophobicContact CG2-CG 4.29Å; I278-W280 HydrophobicContact CG2-CZ2 4.31Å; I278-W280 VanDerWaalsContact O-CD1 3.27Å; I278-W280 PolarHBondContact O-N 2.78Å; W280-A282 PolarHBondContact O-N 3Å; W280-I283 PolarHBondContact O-N 3.36Å; W280-V284 WeakPolarHBondContact O-CG2 3.38Å; W280-V284 PolarHBondContact O-N 3.38Å; W280-I422 HydrophobicContact CH2-CG2 3.95Å; W280-I422 HydrophobicContact CZ3-CG2 3.94Å; W280-I426 HydrophobicContact CZ3-CD1 4.28Å
281	R	88.4	Confident	79.1	Confident	212 Å²	212	67 Å²	67	80%	0.8	38%	0.384	S	S	*	.	H	α-helix	trans	-58.8	-47.6	-179.8	-172.3	177.7	179.7	-177.1	0.1	111.2	P279 I283 T285	P279-R281 VanDerWaalsContact C-N 3.32Å; P279-R281 PolarHBondContact O-N 2.88Å; R281-I283 VanDerWaalsContact C-N 3.33Å; R281-I283 PolarHBondContact O-N 3.37Å; R281-T285 HydrophobicContact CG-CG2 4.45Å; R281-T285 WeakPolarHBondContact O-CB 3.49Å; R281-T285 WeakPolarHBondContact O-CG2 3.12Å; R281-T285 PolarHBondContact O-N 3Å; R281-T285 PolarHBondContact O-OG1 3.34Å
282	A	87.3	Confident	80.9	Confident	36 Å²	36	63.3 Å²	63.3	30%	0.298	36%	0.364	S	S	.	.	H	α-helix	trans	-65.9	-36.5	-179.3	0	0	0	0	0	112.3	P279 W280 S286 W483	P279-A282 HydrophobicContact CB-CB 4.19Å; P279-A282 PolarHBondContact O-N 3.36Å; W280-A282 PolarHBondContact O-N 3Å; A282-S286 WeakPolarHBondContact O-CB 3.49Å; A282-S286 PolarHBondContact O-N 3.46Å; A282-W483 HydrophobicContact CB-CB 3.91Å; A282-W483 HydrophobicContact CB-CG 4.17Å
283	I	90.2	Very high	83	Confident	0 Å²	0	60.7 Å²	60.7	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-63.2	-57.2	176.7	-66.8	169	0	0	0	109.9	I278 P279 W280 R281 T285 S286 L289 L423 I426 W483	I278-I283 HydrophobicContact CG2-CD1 3.82Å; P279-I283 HydrophobicContact CG-CD1 4.26Å; P279-I283 HydrophobicContact CG-CG1 4.35Å; P279-I283 WeakPolarHBondContact O-CG1 3.27Å; P279-I283 PolarHBondContact O-N 3.06Å; W280-I283 PolarHBondContact O-N 3.36Å; R281-I283 VanDerWaalsContact C-N 3.33Å; R281-I283 PolarHBondContact O-N 3.37Å; I283-T285 VanDerWaalsContact C-N 3.32Å; I283-T285 PolarHBondContact O-N 3.4Å; I283-S286 WeakPolarHBondContact O-CB 3.28Å; I283-S286 PolarHBondContact O-N 2.9Å; I283-S286 VanDerWaalsContact O-N 3.11Å; I283-S286 PolarHBondContact O-OG 2.55Å; I283-L289 HydrophobicContact CG2-CD2 3.55Å; I283-L289 VanDerWaalsContact O-CD2 3.29Å; I283-L289 WeakPolarHBondContact O-CD2 3.12Å; I283-L423 HydrophobicContact CG2-CD1 4.26Å; I283-I426 HydrophobicContact CG2-CD1 4.07Å; I283-W483 HydrophobicContact CD1-CZ3 4.27Å; I283-W483 HydrophobicContact CG1-CD2 4.25Å; I283-W483 HydrophobicContact CG1-CE3 3.73Å; I283-W483 HydrophobicContact CG1-CH2 4.09Å; I283-W483 HydrophobicContact CG1-CZ3 3.65Å
284	V	90	Very high	85.2	Confident	72 Å²	72	58.2 Å²	58.2	44%	0.436	33%	0.33	S	S	.	.	H	α-helix	trans	-70.6	-26.2	-173.3	-57.6	0	0	0	0	113.3	W280 S286	W280-V284 WeakPolarHBondContact O-CG2 3.38Å; W280-V284 PolarHBondContact O-N 3.38Å; V284-S286 VanDerWaalsContact C-N 3.32Å
285	T	89.1	Confident	87.7	Confident	101 Å²	101	55.3 Å²	55.3	62%	0.62	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.3	-0.8	174.5	62.2	0	0	0	0	113.4	R281 I283 M287	R281-T285 HydrophobicContact CG-CG2 4.45Å; R281-T285 WeakPolarHBondContact O-CB 3.49Å; R281-T285 WeakPolarHBondContact O-CG2 3.12Å; R281-T285 PolarHBondContact O-N 3Å; R281-T285 PolarHBondContact O-OG1 3.34Å; I283-T285 VanDerWaalsContact C-N 3.32Å; I283-T285 PolarHBondContact O-N 3.4Å; T285-M287 PolarHBondContact O-N 2.98Å
286	S	93	Very high	89.7	Confident	10 Å²	10	50.4 Å²	50.4	7%	0.07	27%	0.267	C	S	.	.			trans	-76.3	123.1	-177.1	71.8	0	0	0	0	111.9	A282 I283 V284 L289 M290	A282-S286 WeakPolarHBondContact O-CB 3.49Å; A282-S286 PolarHBondContact O-N 3.46Å; I283-S286 WeakPolarHBondContact O-CB 3.28Å; I283-S286 PolarHBondContact O-N 2.9Å; I283-S286 VanDerWaalsContact O-N 3.11Å; I283-S286 PolarHBondContact O-OG 2.55Å; V284-S286 VanDerWaalsContact C-N 3.32Å; S286-L289 PolarHBondContact O-N 3.19Å; S286-L289 WeakPolarHBondContact OG-CB 3.32Å; S286-M290 PolarHBondContact O-N 3.33Å
287	M	94.3	Very high	91.4	Very high	97 Å²	97	50.1 Å²	50.1	48%	0.478	25%	0.248	S	C	.	.	H	α-helix	trans	-58.9	-38.8	179.9	-170.3	61	71.4	0	0	113.5	T285 L289 M290 A291 F471 F475	T285-M287 PolarHBondContact O-N 2.98Å; M287-L289 PolarHBondContact O-N 3.45Å; M287-M290 PolarHBondContact O-N 3.02Å; M287-A291 PolarHBondContact O-N 3.46Å; M287-F471 HydrophobicContact SD-CZ 4.37Å; M287-F475 HydrophobicContact CG-CB 3.9Å; M287-F475 HydrophobicContact CG-CD1 3.56Å; M287-F475 HydrophobicContact CG-CE1 4.37Å; M287-F475 HydrophobicContact CG-CG 3.91Å; M287-F475 HydrophobicContact SD-CB 4.29Å; M287-F475 HydrophobicContact SD-CD1 3.82Å; M287-F475 HydrophobicContact SD-CD2 4.48Å; M287-F475 HydrophobicContact SD-CE1 4.27Å; M287-F475 HydrophobicContact SD-CG 3.93Å
288	P	93.4	Very high	92.4	Very high	11 Å²	11	43 Å²	43	7%	0.071	22%	0.215	C	C	.	.	H	α-helix	trans	-65.1	-35.2	176.3	-26.5	39.5	0	0	0	113.7	A291 I292 R477	P288-A291 WeakPolarHBondContact O-CB 3.31Å; P288-A291 PolarHBondContact O-N 3.36Å; P288-I292 WeakPolarHBondContact O-CG1 3.44Å; P288-I292 PolarHBondContact O-N 3.2Å; P288-R477 HydrophobicContact CB-CB 4.05Å; P288-R477 HydrophobicContact CB-CG 4.18Å; P288-R477 HydrophobicContact CG-CB 3.96Å; P288-R477 HydrophobicContact CG-CG 3.63Å
289	L	94.3	Very high	93	Very high	2 Å²	2	42.7 Å²	42.7	1%	0.01	21%	0.212	C	C	.	.	H	α-helix	trans	-67.5	-45.4	173.6	-178.3	63.9	0	0	0	110.5	I283 S286 M287 A291 I292 V293 L423 T427	I283-L289 HydrophobicContact CG2-CD2 3.55Å; I283-L289 VanDerWaalsContact O-CD2 3.29Å; I283-L289 WeakPolarHBondContact O-CD2 3.12Å; S286-L289 PolarHBondContact O-N 3.19Å; S286-L289 WeakPolarHBondContact OG-CB 3.32Å; M287-L289 PolarHBondContact O-N 3.45Å; L289-A291 PolarHBondContact O-N 2.96Å; L289-I292 CarbonylContact O-C 3.54Å; L289-I292 WeakPolarHBondContact O-CA 3.45Å; L289-I292 WeakPolarHBondContact O-CB 3.39Å; L289-I292 PolarHBondContact O-N 2.85Å; L289-V293 HydrophobicContact CG-CG2 4.37Å; L289-V293 WeakPolarHBondContact O-CG2 3.33Å; L289-V293 PolarHBondContact O-N 3.15Å; L289-L423 HydrophobicContact CD1-CB 4.34Å; L289-L423 HydrophobicContact CD1-CD2 4.29Å; L289-L423 HydrophobicContact CD1-CG 3.94Å; L289-T427 HydrophobicContact CD1-CG2 3.65Å
290	M	96	Very high	93.2	Very high	79 Å²	79	41.6 Å²	41.6	39%	0.389	20%	0.204	S	C	.	.	H	α-helix	trans	-58.4	-37.3	176.4	-69	-54.8	-60.2	0	0	112.1	S286 M287 I292 V293 V294	S286-M290 PolarHBondContact O-N 3.33Å; M287-M290 PolarHBondContact O-N 3.02Å; M290-I292 VanDerWaalsContact C-N 3.34Å; M290-I292 PolarHBondContact O-N 3.04Å; M290-V293 PolarHBondContact O-N 2.96Å; M290-V294 WeakPolarHBondContact O-CG2 3.38Å; M290-V294 PolarHBondContact O-N 3.16Å
291	A	96.3	Very high	93.3	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-59.8	-44.2	173	0	0	0	0	0	112.2	M287 P288 L289 A295 F471 Y472 F475	M287-A291 PolarHBondContact O-N 3.46Å; P288-A291 WeakPolarHBondContact O-CB 3.31Å; P288-A291 PolarHBondContact O-N 3.36Å; L289-A291 PolarHBondContact O-N 2.96Å; A291-A295 WeakPolarHBondContact O-CB 3.19Å; A291-A295 PolarHBondContact O-N 2.84Å; A291-F471 HydrophobicContact CB-CD1 4.45Å; A291-F471 HydrophobicContact CB-CE1 4.38Å; A291-Y472 HydrophobicContact CB-CD2 4.05Å; A291-F475 HydrophobicContact CB-CB 3.8Å
292	I	95.6	Very high	93.4	Very high	0 Å²	0	27.9 Å²	27.9	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-67.5	-41.4	176.8	-60.6	164.8	0	0	0	110.8	P288 L289 M290 V294 A295 H296 F408 N411 H412 I415 T427 Y472	P288-I292 WeakPolarHBondContact O-CG1 3.44Å; P288-I292 PolarHBondContact O-N 3.2Å; L289-I292 CarbonylContact O-C 3.54Å; L289-I292 WeakPolarHBondContact O-CA 3.45Å; L289-I292 WeakPolarHBondContact O-CB 3.39Å; L289-I292 PolarHBondContact O-N 2.85Å; M290-I292 VanDerWaalsContact C-N 3.34Å; M290-I292 PolarHBondContact O-N 3.04Å; I292-V294 PolarHBondContact O-N 3.43Å; I292-A295 PolarHBondContact O-N 2.86Å; I292-H296 WeakPolarHBondContact O-CB 3.16Å; I292-H296 PolarHBondContact O-N 3.47Å; I292-F408 HydrophobicContact CG2-CD2 4.32Å; I292-N411 HydrophobicContact CD1-CB 3.93Å; I292-N411 HydrophobicContact CG1-CB 4.24Å; I292-H412 WeakPolarHBondContact CG2-CE1 3.41Å; I292-H412 WeakPolarHBondContact CG2-NE2 3.23Å; I292-I415 HydrophobicContact CD1-CD1 3.58Å; I292-I415 HydrophobicContact CD1-CG1 4.25Å; I292-T427 HydrophobicContact CB-CG2 4.45Å; I292-T427 HydrophobicContact CG2-CG2 4.02Å; I292-Y472 HydrophobicContact CG1-CE2 3.95Å
293	V	96.3	Very high	93.3	Very high	12 Å²	12	26.9 Å²	26.9	7%	0.073	14%	0.142	C	C	.	.	H	α-helix	trans	-56.8	-50.4	176.7	170.7	0	0	0	0	110.8	L289 M290 H296 F297 T427 F430	L289-V293 HydrophobicContact CG-CG2 4.37Å; L289-V293 WeakPolarHBondContact O-CG2 3.33Å; L289-V293 PolarHBondContact O-N 3.15Å; M290-V293 PolarHBondContact O-N 2.96Å; V293-H296 PolarHBondContact O-N 3.48Å; V293-F297 WeakPolarHBondContact O-CB 3.24Å; V293-F297 PolarHBondContact O-N 3Å; V293-T427 HydrophobicContact CG2-CG2 3.62Å; V293-F430 HydrophobicContact CG1-CB 3.8Å; V293-F430 HydrophobicContact CG1-CD2 3.9Å; V293-F430 HydrophobicContact CG1-CG 3.88Å
294	V	96.7	Very high	93	Very high	27 Å²	27	27 Å²	27	16%	0.164	14%	0.143	C	C	.	.	H	α-helix	trans	-63.8	-44.6	179.9	173.2	0	0	0	0	110.8	M290 I292 H296 F297 S298 F467 F471	M290-V294 WeakPolarHBondContact O-CG2 3.38Å; M290-V294 PolarHBondContact O-N 3.16Å; I292-V294 PolarHBondContact O-N 3.43Å; V294-H296 PolarHBondContact O-N 3.35Å; V294-F297 PolarHBondContact O-N 3.24Å; V294-S298 WeakPolarHBondContact O-CB 3.28Å; V294-S298 PolarHBondContact O-N 2.84Å; V294-S298 PolarHBondContact O-OG 2.95Å; V294-F467 HydrophobicContact CG1-CD1 4.14Å; V294-F467 HydrophobicContact CG1-CE1 3.78Å; V294-F471 HydrophobicContact CB-CD1 3.76Å; V294-F471 HydrophobicContact CB-CE1 4.2Å; V294-F471 HydrophobicContact CB-CG 4.4Å; V294-F471 HydrophobicContact CG1-CB 4.01Å; V294-F471 HydrophobicContact CG1-CD1 3.89Å; V294-F471 HydrophobicContact CG1-CG 4.03Å; V294-F471 HydrophobicContact CG2-CD1 3.91Å; V294-F471 HydrophobicContact CG2-CE1 3.88Å
295	A	96.3	Very high	92.6	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-60.9	-44.5	176.5	0	0	0	0	0	112.3	A291 I292 S298 Y299 M370 F408 Y472	A291-A295 WeakPolarHBondContact O-CB 3.19Å; A291-A295 PolarHBondContact O-N 2.84Å; I292-A295 PolarHBondContact O-N 2.86Å; A295-S298 PolarHBondContact O-N 3.41Å; A295-Y299 WeakPolarHBondContact O-CB 3.28Å; A295-Y299 PolarHBondContact O-N 3.01Å; A295-M370 HydrophobicContact CB-SD 4.33Å; A295-F408 HydrophobicContact CB-CB 4.02Å; A295-F408 HydrophobicContact CB-CD1 4.08Å; A295-F408 HydrophobicContact CB-CD2 4.23Å; A295-F408 HydrophobicContact CB-CG 3.83Å; A295-Y472 HydrophobicContact CB-CD2 3.94Å; A295-Y472 HydrophobicContact CB-CG 4.12Å
296	H	95.4	Very high	92.2	Very high	11 Å²	11	19.5 Å²	19.5	5%	0.051	10%	0.097	C	C	.	.	H	α-helix	trans	-68.4	-40.7	-177.2	-163.5	-168.7	0	0	0	111.5	I292 V293 V294 N300 F408 T427 A431	I292-H296 WeakPolarHBondContact O-CB 3.16Å; I292-H296 PolarHBondContact O-N 3.47Å; V293-H296 PolarHBondContact O-N 3.48Å; V294-H296 PolarHBondContact O-N 3.35Å; H296-N300 PolarHBondContact CD2-ND2 3.15Å; H296-N300 PolarHBondContact NE2-ND2 3.44Å; H296-N300 WeakPolarHBondContact O-CB 3.45Å; H296-N300 PolarHBondContact O-N 3.42Å; H296-N300 PolarHBondContact O-ND2 3.19Å; H296-F408 HydrophobicContact CB-CD2 4.19Å; H296-F408 HydrophobicContact CB-CE2 3.65Å; H296-F408 HydrophobicContact CB-CZ 4.41Å; H296-F408 AromaticContact CD2-CE2 3.55Å; H296-F408 AromaticContact CD2-CZ 3.97Å; H296-F408 AromaticContact CG-CE2 3.75Å; H296-T427 PolarHBondContact ND1-OG1 3.19Å; H296-A431 HydrophobicContact CB-CB 3.98Å; H296-A431 VanDerWaalsContact CG-CB 3.43Å
297	F	95.4	Very high	91.3	Very high	58 Å²	58	19.6 Å²	19.6	25%	0.254	10%	0.096	S	C	.	.	H	α-helix	trans	-58.5	-52	170.7	176.1	-86.2	0	0	0	111.5	V293 V294 Y299 N300 W301 F430 I433 P434 I464	V293-F297 WeakPolarHBondContact O-CB 3.24Å; V293-F297 PolarHBondContact O-N 3Å; V294-F297 PolarHBondContact O-N 3.24Å; F297-Y299 PolarHBondContact O-N 2.8Å; F297-N300 PolarHBondContact O-N 2.96Å; F297-W301 HydrophobicContact CE1-CE3 4.16Å; F297-W301 AromaticContact CZ-CE3 3.92Å; F297-W301 HydrophobicContact CZ-CE3 3.92Å; F297-W301 HydrophobicContact CZ-CZ3 4.16Å; F297-W301 PolarHBondContact O-N 3.27Å; F297-F430 WeakPolarHBondContact CD2-O 3.37Å; F297-I433 HydrophobicContact CE2-CB 4.24Å; F297-I433 HydrophobicContact CE2-CG2 4.33Å; F297-P434 HydrophobicContact CD2-CG 3.63Å; F297-P434 HydrophobicContact CE1-CG 4.44Å; F297-P434 HydrophobicContact CE2-CG 3.55Å; F297-P434 HydrophobicContact CG-CG 4.12Å; F297-P434 HydrophobicContact CZ-CG 3.98Å; F297-I464 HydrophobicContact CD1-CG2 4.44Å; F297-I464 HydrophobicContact CE1-CG2 4.28Å
298	S	95.1	Very high	90.2	Very high	2 Å²	2	16 Å²	16	1%	0.014	8%	0.08	C	C	.	.	H	α-helix	trans	-62.5	-45	-177.2	-71.9	0	0	0	0	112.6	V294 A295 W301 M370 I464 N465 G468	V294-S298 WeakPolarHBondContact O-CB 3.28Å; V294-S298 PolarHBondContact O-N 2.84Å; V294-S298 PolarHBondContact O-OG 2.95Å; A295-S298 PolarHBondContact O-N 3.41Å; S298-W301 WeakPolarHBondContact O-CB 3.22Å; S298-W301 PolarHBondContact O-N 2.95Å; S298-M370 VanDerWaalsContact CB-CE 3.44Å; S298-I464 VanDerWaalsContact CB-O 3.26Å; S298-I464 WeakPolarHBondContact CB-O 3.46Å; S298-I464 PolarHBondContact OG-O 3.46Å; S298-N465 PolarHBondContact O-OD1 3.09Å; S298-G468 WeakPolarHBondContact OG-CA 3.42Å
299	Y	93.9	Very high	89.2	Confident	30 Å²	30	16.3 Å²	16.3	12%	0.118	8%	0.081	C	C	.	.	H	α-helix	trans	-60.4	-47.8	176.6	175.7	-95.9	0	0	0	111.8	A295 F297 W301 T302 F303 G401 F408	A295-Y299 WeakPolarHBondContact O-CB 3.28Å; A295-Y299 PolarHBondContact O-N 3.01Å; F297-Y299 PolarHBondContact O-N 2.8Å; Y299-W301 VanDerWaalsContact C-N 3.26Å; Y299-W301 PolarHBondContact O-N 3.05Å; Y299-T302 PolarHBondContact O-N 3.32Å; Y299-F303 HydrophobicContact CE1-CB 4.33Å; Y299-F303 PolarHBondContact O-N 3.31Å; Y299-G401 VanDerWaalsContact CE2-O 3.32Å; Y299-G401 WeakPolarHBondContact CE2-O 3.15Å; Y299-F408 HydrophobicContact CD1-CE1 4.49Å; Y299-F408 HydrophobicContact CD1-CZ 4.01Å; Y299-F408 HydrophobicContact CD2-CE1 4.29Å; Y299-F408 AromaticContact CG-CE1 3.92Å; Y299-F408 HydrophobicContact CG-CE1 3.92Å; Y299-F408 AromaticContact CG-CZ 3.85Å; Y299-F408 HydrophobicContact CG-CZ 3.85Å
300	N	91.8	Very high	88.2	Confident	8 Å²	8	16.5 Å²	16.5	4%	0.043	8%	0.082	C	C	.	.	H	α-helix	trans	-67.8	-26.1	-179.5	-86.7	-69.2	0	0	0	113.4	H296 F297 T302 F303 Y304 A431	H296-N300 PolarHBondContact CD2-ND2 3.15Å; H296-N300 PolarHBondContact NE2-ND2 3.44Å; H296-N300 WeakPolarHBondContact O-CB 3.45Å; H296-N300 PolarHBondContact O-N 3.42Å; H296-N300 PolarHBondContact O-ND2 3.19Å; F297-N300 PolarHBondContact O-N 2.96Å; N300-T302 VanDerWaalsContact C-N 3.33Å; N300-T302 PolarHBondContact O-N 3.02Å; N300-F303 PolarHBondContact O-N 2.83Å; N300-Y304 HydrophobicContact CB-CD2 3.87Å; N300-Y304 HydrophobicContact CB-CE2 3.71Å; N300-Y304 WeakPolarHBondContact O-CB 3.29Å; N300-Y304 VanDerWaalsContact O-CD2 3.29Å; N300-Y304 WeakPolarHBondContact O-CD2 3.38Å; N300-Y304 PolarHBondContact O-N 3.09Å; N300-Y304 VanDerWaalsContact OD1-CE2 3.3Å; N300-Y304 WeakPolarHBondContact OD1-CE2 3.38Å; N300-A431 HydrophobicContact CB-CB 4.26Å; N300-A431 WeakPolarHBondContact CB-O 3.05Å; N300-A431 WeakPolarHBondContact ND2-CB 3.47Å
301	W	91.3	Very high	87	Confident	21 Å²	21	12.9 Å²	12.9	8%	0.08	6%	0.064	C	C	.	.	H	α-helix	trans	-55.1	-51.5	171.1	-171.8	-78.4	0	0	0	111.5	F297 S298 Y299 T305 P434 I441 I460 I464	F297-W301 HydrophobicContact CE1-CE3 4.16Å; F297-W301 AromaticContact CZ-CE3 3.92Å; F297-W301 HydrophobicContact CZ-CE3 3.92Å; F297-W301 HydrophobicContact CZ-CZ3 4.16Å; F297-W301 PolarHBondContact O-N 3.27Å; S298-W301 WeakPolarHBondContact O-CB 3.22Å; S298-W301 PolarHBondContact O-N 2.95Å; Y299-W301 VanDerWaalsContact C-N 3.26Å; Y299-W301 PolarHBondContact O-N 3.05Å; W301-T305 WeakPolarHBondContact O-CB 3.37Å; W301-T305 PolarHBondContact O-N 3.36Å; W301-T305 PolarHBondContact O-OG1 3.46Å; W301-P434 VanDerWaalsContact CA-CB 3.47Å; W301-P434 HydrophobicContact CB-CB 3.94Å; W301-P434 HydrophobicContact CB-CG 4.24Å; W301-P434 HydrophobicContact CD2-CB 4.12Å; W301-P434 HydrophobicContact CE3-CB 3.55Å; W301-P434 HydrophobicContact CE3-CG 3.93Å; W301-P434 HydrophobicContact CG-CB 4.34Å; W301-P434 HydrophobicContact CZ3-CB 4.33Å; W301-I441 HydrophobicContact CH2-CD1 4.01Å; W301-I460 HydrophobicContact CZ2-CG2 3.99Å; W301-I464 HydrophobicContact CB-CG2 4.05Å; W301-I464 HydrophobicContact CD2-CD1 3.53Å; W301-I464 HydrophobicContact CE3-CD1 3.94Å; W301-I464 HydrophobicContact CG-CD1 3.88Å; W301-I464 HydrophobicContact CG-CG2 4.21Å; W301-I464 HydrophobicContact CH2-CD1 4.33Å; W301-I464 HydrophobicContact CZ2-CD1 3.95Å; W301-I464 HydrophobicContact CZ3-CD1 4.34Å
302	T	88.9	Confident	85.7	Confident	8 Å²	8	14.8 Å²	14.8	5%	0.049	8%	0.076	C	C	.	.	H	α-helix	trans	-68.8	-44.1	179.6	-57.8	0	0	0	0	111.3	Y299 N300 T305 L306 L377 N465	Y299-T302 PolarHBondContact O-N 3.32Å; N300-T302 VanDerWaalsContact C-N 3.33Å; N300-T302 PolarHBondContact O-N 3.02Å; T302-T305 PolarHBondContact O-N 2.97Å; T302-L306 HydrophobicContact CG2-CD1 4.14Å; T302-L306 WeakPolarHBondContact O-CG 3.3Å; T302-L306 PolarHBondContact O-N 3.26Å; T302-L377 HydrophobicContact CG2-CD2 4.22Å; T302-N465 VanDerWaalsContact OG1-CG 3.29Å; T302-N465 PolarHBondContact OG1-ND2 2.97Å; T302-N465 PolarHBondContact OG1-OD1 3.08Å
303	F	86.3	Confident	84.7	Confident	16 Å²	16	15.4 Å²	15.4	7%	0.07	8%	0.078	C	C	.	.	H	α-helix	trans	-59.8	-50.5	-179.2	-178.7	-102.3	0	0	0	112.2	Y51 Y299 N300 L306 L307 Y333	Y51-F303 HydrophobicContact CE1-CE1 4.34Å; Y51-F303 HydrophobicContact CE1-CZ 4.27Å; Y299-F303 HydrophobicContact CE1-CB 4.33Å; Y299-F303 PolarHBondContact O-N 3.31Å; N300-F303 PolarHBondContact O-N 2.83Å; F303-L306 PolarHBondContact O-N 3.46Å; F303-L307 HydrophobicContact CE1-CD2 4.11Å; F303-L307 VanDerWaalsContact O-CB 3.32Å; F303-L307 WeakPolarHBondContact O-CB 3.22Å; F303-L307 PolarHBondContact O-N 3.04Å; F303-Y333 HydrophobicContact CD2-CE1 4.45Å; F303-Y333 AromaticContact CE2-CD1 3.99Å; F303-Y333 HydrophobicContact CE2-CD1 3.99Å; F303-Y333 AromaticContact CE2-CE1 3.82Å; F303-Y333 HydrophobicContact CE2-CE1 3.82Å; F303-Y333 HydrophobicContact CZ-CE1 4.33Å
304	Y	83.8	Confident	83.6	Confident	2 Å²	2	14.9 Å²	14.9	1%	0.008	8%	0.075	C	C	.	.	H	α-helix	trans	-73.1	-33.4	-179.3	-66.6	-44.3	0	0	0	113.2	F113 N300 L306 L307 T308 A431	F113-Y304 HydrophobicContact CE1-CD1 4.07Å; F113-Y304 HydrophobicContact CE1-CD2 4.38Å; F113-Y304 AromaticContact CE1-CE1 3.83Å; F113-Y304 HydrophobicContact CE1-CE1 3.83Å; F113-Y304 HydrophobicContact CE1-CE2 4.14Å; F113-Y304 HydrophobicContact CE1-CG 4.36Å; F113-Y304 AromaticContact CE1-CZ 3.87Å; F113-Y304 AromaticContact CZ-CD1 3.95Å; F113-Y304 HydrophobicContact CZ-CD1 3.95Å; F113-Y304 HydrophobicContact CZ-CE1 4.11Å; F113-Y304 HydrophobicContact CZ-CG 4.27Å; N300-Y304 HydrophobicContact CB-CD2 3.87Å; N300-Y304 HydrophobicContact CB-CE2 3.71Å; N300-Y304 WeakPolarHBondContact O-CB 3.29Å; N300-Y304 VanDerWaalsContact O-CD2 3.29Å; N300-Y304 WeakPolarHBondContact O-CD2 3.38Å; N300-Y304 PolarHBondContact O-N 3.09Å; N300-Y304 VanDerWaalsContact OD1-CE2 3.3Å; N300-Y304 WeakPolarHBondContact OD1-CE2 3.38Å; Y304-L306 VanDerWaalsContact C-N 3.32Å; Y304-L306 PolarHBondContact O-N 2.92Å; Y304-L307 HydrophobicContact CD1-CD2 4.13Å; Y304-L307 PolarHBondContact O-N 2.69Å; Y304-T308 WeakPolarHBondContact O-CB 3.49Å; Y304-T308 WeakPolarHBondContact O-CG2 3.22Å; Y304-T308 PolarHBondContact O-N 3.39Å; Y304-T308 PolarHBondContact O-OG1 3.18Å; Y304-A431 WeakPolarHBondContact CE2-O 3.16Å
305	T	80.6	Confident	82.3	Confident	7 Å²	7	15.8 Å²	15.8	4%	0.043	8%	0.079	C	C	.	.	H	α-helix	trans	-58.1	-48.5	172.6	-60.9	0	0	0	0	109.8	W301 T302 L309 V457	W301-T305 WeakPolarHBondContact O-CB 3.37Å; W301-T305 PolarHBondContact O-N 3.36Å; W301-T305 PolarHBondContact O-OG1 3.46Å; T302-T305 PolarHBondContact O-N 2.97Å; T305-L309 HydrophobicContact CG2-CD1 3.87Å; T305-L309 VanDerWaalsContact O-CB 3.23Å; T305-L309 WeakPolarHBondContact O-CB 3.34Å; T305-L309 PolarHBondContact O-N 3.49Å; T305-V457 HydrophobicContact CG2-CG1 4.03Å
306	L	80.8	Confident	80.9	Confident	9 Å²	9	18.9 Å²	18.9	5%	0.047	10%	0.095	C	C	.	.	H	α-helix	trans	-66.2	-43.2	174.8	-65.8	176.3	0	0	0	111.5	T302 F303 Y304 T308 L310 Y333 L377 L394 S398	T302-L306 HydrophobicContact CG2-CD1 4.14Å; T302-L306 WeakPolarHBondContact O-CG 3.3Å; T302-L306 PolarHBondContact O-N 3.26Å; F303-L306 PolarHBondContact O-N 3.46Å; Y304-L306 VanDerWaalsContact C-N 3.32Å; Y304-L306 PolarHBondContact O-N 2.92Å; L306-T308 VanDerWaalsContact C-N 3.32Å; L306-T308 PolarHBondContact O-N 3Å; L306-L310 WeakPolarHBondContact O-CA 3.37Å; L306-L310 WeakPolarHBondContact O-CB 3.48Å; L306-L310 PolarHBondContact O-N 2.93Å; L306-Y333 VanDerWaalsContact C-OH 3.3Å; L306-Y333 PolarHBondContact O-OH 3.18Å; L306-L377 HydrophobicContact CD2-CD1 3.99Å; L306-L394 HydrophobicContact CD2-CD2 3.91Å; L306-S398 WeakPolarHBondContact CD1-OG 2.99Å
307	L	74.4	Confident	79.5	Confident	12 Å²	12	19.6 Å²	19.6	6%	0.063	10%	0.1	C	C	.	.	H	α-helix	trans	-59.5	-41.4	-178.8	-166.8	70.9	0	0	0	113.9	V55 T207 F303 Y304 Y333	V55-L307 HydrophobicContact CG1-CD1 3.96Å; V55-L307 HydrophobicContact CG1-CD2 4.46Å; T207-L307 HydrophobicContact CG2-CD1 4.09Å; F303-L307 HydrophobicContact CE1-CD2 4.11Å; F303-L307 VanDerWaalsContact O-CB 3.32Å; F303-L307 WeakPolarHBondContact O-CB 3.22Å; F303-L307 PolarHBondContact O-N 3.04Å; Y304-L307 HydrophobicContact CD1-CD2 4.13Å; Y304-L307 PolarHBondContact O-N 2.69Å; L307-Y333 WeakPolarHBondContact CA-OH 3.44Å; L307-Y333 HydrophobicContact CD1-CE1 3.79Å; L307-Y333 HydrophobicContact CD1-CE2 4.34Å; L307-Y333 PolarHBondContact N-OH 3.37Å; L307-Y333 VanDerWaalsContact N-OH 3.15Å
308	T	71.1	Confident	78.2	Confident	21 Å²	21	17 Å²	17	13%	0.129	9%	0.089	C	C	.	.	H	α-helix	trans	-88.4	-36.7	-173.2	54	0	0	0	0	112.5	Y304 L306 P439	Y304-T308 WeakPolarHBondContact O-CB 3.49Å; Y304-T308 WeakPolarHBondContact O-CG2 3.22Å; Y304-T308 PolarHBondContact O-N 3.39Å; Y304-T308 PolarHBondContact O-OG1 3.18Å; L306-T308 VanDerWaalsContact C-N 3.32Å; L306-T308 PolarHBondContact O-N 3Å; T308-P439 HydrophobicContact CG2-CG 4.11Å
309	L	72.4	Confident	76.7	Confident	18 Å²	18	18.7 Å²	18.7	9%	0.094	11%	0.106	C	C	.	.	H	α-helix	trans	-106.2	-17.6	-169.5	-57.2	174.1	0	0	0	114.1	T305 T312 Y313 A442 W454	T305-L309 HydrophobicContact CG2-CD1 3.87Å; T305-L309 VanDerWaalsContact O-CB 3.23Å; T305-L309 WeakPolarHBondContact O-CB 3.34Å; T305-L309 PolarHBondContact O-N 3.49Å; L309-T312 PolarHBondContact O-N 3.43Å; L309-Y313 WeakPolarHBondContact O-CB 3.47Å; L309-Y313 PolarHBondContact O-N 3.49Å; L309-A442 HydrophobicContact CD1-CB 3.15Å; L309-A442 HydrophobicContact CG-CB 4.45Å; L309-W454 HydrophobicContact CB-CH2 3.88Å; L309-W454 HydrophobicContact CB-CZ3 4.17Å; L309-W454 HydrophobicContact CD1-CH2 4.2Å; L309-W454 HydrophobicContact CD1-CZ3 4.17Å; L309-W454 HydrophobicContact CG-CH2 4.5Å
310	L	74.8	Confident	75.7	Confident	5 Å²	5	18.4 Å²	18.4	3%	0.026	11%	0.105	C	C	.	.	H	α-helix	trans	-57.3	-43.6	179.8	-175.3	70.3	0	0	0	112.4	L306 T312 Y313 M314 P332 Y333 L394	L306-L310 WeakPolarHBondContact O-CA 3.37Å; L306-L310 WeakPolarHBondContact O-CB 3.48Å; L306-L310 PolarHBondContact O-N 2.93Å; L310-T312 VanDerWaalsContact C-N 3.32Å; L310-T312 PolarHBondContact O-N 3.02Å; L310-Y313 PolarHBondContact O-N 3.18Å; L310-M314 HydrophobicContact CD1-CE 3.43Å; L310-M314 VanDerWaalsContact CD1-CE 3.43Å; L310-M314 HydrophobicContact CD1-CG 4.27Å; L310-M314 HydrophobicContact CD2-CE 4.44Å; L310-M314 HydrophobicContact CG-CE 3.96Å; L310-M314 HydrophobicContact CG-CG 4.2Å; L310-M314 WeakPolarHBondContact O-CB 3.17Å; L310-M314 WeakPolarHBondContact O-CG 3.46Å; L310-M314 PolarHBondContact O-N 3.36Å; L310-P332 HydrophobicContact CD2-CG 4.01Å; L310-Y333 HydrophobicContact CD2-CE2 4.4Å; L310-L394 HydrophobicContact CD1-CD1 3.69Å
311	P	69.4	Low	74.6	Confident	4 Å²	4	20 Å²	20	3%	0.026	12%	0.117	C	C	.	.	H	α-helix	trans	-63.2	-38.5	178.7	-22.6	35.3	0	0	0	112.5	N315 N325	P311-N315 WeakPolarHBondContact O-CB 3.42Å; P311-N315 PolarHBondContact O-N 3.06Å; P311-N315 VanDerWaalsContact O-N 3.08Å; P311-N325 WeakPolarHBondContact CA-OD1 3.41Å; P311-N325 PolarHBondContact O-ND2 3.04Å
312	T	70.1	Confident	73.3	Confident	40 Å²	40	21.5 Å²	21.5	25%	0.245	13%	0.126	C	C	.	.	H	α-helix	trans	-67.8	-43.8	176	-51.1	0	0	0	0	111.1	L309 L310 M314 N315 D316	L309-T312 PolarHBondContact O-N 3.43Å; L310-T312 VanDerWaalsContact C-N 3.32Å; L310-T312 PolarHBondContact O-N 3.02Å; T312-M314 VanDerWaalsContact C-N 3.34Å; T312-M314 PolarHBondContact O-N 2.98Å; T312-N315 PolarHBondContact O-N 3.35Å; T312-D316 WeakPolarHBondContact CG2-OD2 3.26Å; T312-D316 VanDerWaalsContact O-CB 3.31Å; T312-D316 WeakPolarHBondContact O-CB 3.32Å; T312-D316 PolarHBondContact O-N 3.3Å
313	Y	73.6	Confident	72.1	Confident	13 Å²	13	24 Å²	24	5%	0.051	14%	0.138	C	C	.	.	I	π-helix	trans	-59.7	-43.7	175.2	178.8	-102.7	0	0	0	111.9	L309 L310 N315 I317 L318 L394 W454	L309-Y313 WeakPolarHBondContact O-CB 3.47Å; L309-Y313 PolarHBondContact O-N 3.49Å; L310-Y313 PolarHBondContact O-N 3.18Å; Y313-N315 PolarHBondContact O-N 3.15Å; Y313-I317 HydrophobicContact CD2-CB 3.98Å; Y313-I317 HydrophobicContact CD2-CG1 3.67Å; Y313-I317 HydrophobicContact CD2-CG2 4.39Å; Y313-I317 HydrophobicContact CE2-CB 4.01Å; Y313-I317 HydrophobicContact CE2-CG1 4Å; Y313-I317 HydrophobicContact CE2-CG2 3.91Å; Y313-I317 VanDerWaalsContact O-CB 3.26Å; Y313-I317 WeakPolarHBondContact O-CB 3.39Å; Y313-I317 PolarHBondContact O-N 3.46Å; Y313-I317 VanDerWaalsContact O-N 3.09Å; Y313-L318 HydrophobicContact CD1-CD1 4.1Å; Y313-L318 HydrophobicContact CD1-CG 4.28Å; Y313-L318 HydrophobicContact CE1-CD1 3.8Å; Y313-L318 HydrophobicContact CE1-CD2 4Å; Y313-L318 HydrophobicContact CE1-CG 3.97Å; Y313-L318 PolarHBondContact O-N 3.28Å; Y313-L318 VanDerWaalsContact O-N 3.16Å; Y313-L394 HydrophobicContact CD1-CD1 4.26Å; Y313-L394 HydrophobicContact CE1-CD1 3.96Å; Y313-W454 AromaticContact CD2-CD2 3.63Å; Y313-W454 HydrophobicContact CD2-CD2 3.63Å; Y313-W454 AromaticContact CD2-CE2 3.73Å; Y313-W454 AromaticContact CD2-CE3 4Å; Y313-W454 HydrophobicContact CD2-CE3 4Å; Y313-W454 AromaticContact CD2-CG 3.96Å; Y313-W454 HydrophobicContact CD2-CG 3.96Å; Y313-W454 HydrophobicContact CD2-CZ2 4.19Å; Y313-W454 HydrophobicContact CD2-CZ3 4.43Å; Y313-W454 HydrophobicContact CE2-CB 4.31Å; Y313-W454 HydrophobicContact CE2-CD2 4.06Å; Y313-W454 AromaticContact CE2-CG 3.92Å; Y313-W454 HydrophobicContact CE2-CG 3.92Å
314	M	73.4	Confident	71.4	Confident	0 Å²	0	27 Å²	27	0%	0	15%	0.151	C	C	.	.	I	π-helix	trans	-66	-36.2	178.8	-68.4	-81.8	173.8	0	0	112.8	L310 T312 L318 G319 F320 N325 L328 V391 L394	L310-M314 HydrophobicContact CD1-CE 3.43Å; L310-M314 VanDerWaalsContact CD1-CE 3.43Å; L310-M314 HydrophobicContact CD1-CG 4.27Å; L310-M314 HydrophobicContact CD2-CE 4.44Å; L310-M314 HydrophobicContact CG-CE 3.96Å; L310-M314 HydrophobicContact CG-CG 4.2Å; L310-M314 WeakPolarHBondContact O-CB 3.17Å; L310-M314 WeakPolarHBondContact O-CG 3.46Å; L310-M314 PolarHBondContact O-N 3.36Å; T312-M314 VanDerWaalsContact C-N 3.34Å; T312-M314 PolarHBondContact O-N 2.98Å; M314-L318 HydrophobicContact CE-CD1 4.32Å; M314-L318 HydrophobicContact CG-CD1 4.42Å; M314-L318 CarbonylContact O-C 3.56Å; M314-L318 WeakPolarHBondContact O-CB 3.41Å; M314-L318 HydrophobicContact SD-CD1 3.5Å; M314-L318 WeakPolarHBondContact SD-CD1 3.4Å; M314-G319 PolarHBondContact O-N 2.76Å; M314-F320 HydrophobicContact CB-CD2 4.4Å; M314-F320 PolarHBondContact O-N 3.42Å; M314-F320 HydrophobicContact SD-CD2 4.07Å; M314-F320 HydrophobicContact SD-CE2 4.2Å; M314-N325 WeakPolarHBondContact CB-OD1 3.29Å; M314-L328 HydrophobicContact SD-CB 4.41Å; M314-V391 HydrophobicContact CE-CB 4.41Å; M314-V391 HydrophobicContact CE-CG1 4.28Å; M314-V391 HydrophobicContact CE-CG2 3.78Å; M314-V391 HydrophobicContact SD-CG2 3.81Å; M314-L394 HydrophobicContact CE-CD1 4.1Å
315	N	68.7	Low	70.9	Confident	46 Å²	46	27.2 Å²	27.2	25%	0.246	15%	0.153	C	C	.	.	I	π-helix	trans	-80.5	-55.5	178.5	-174.9	72	0	0	0	112.1	P311 T312 Y313 G319 F320	P311-N315 WeakPolarHBondContact O-CB 3.42Å; P311-N315 PolarHBondContact O-N 3.06Å; P311-N315 VanDerWaalsContact O-N 3.08Å; T312-N315 PolarHBondContact O-N 3.35Å; Y313-N315 PolarHBondContact O-N 3.15Å; N315-G319 WeakPolarHBondContact O-CA 3.33Å; N315-G319 PolarHBondContact O-N 3Å; N315-G319 VanDerWaalsContact O-N 3.14Å; N315-F320 PolarHBondContact OD1-O 3Å
316	D	67.6	Low	70.6	Confident	65 Å²	65	27 Å²	27	35%	0.348	15%	0.152	S	C	.	.	I	π-helix	trans	-81.1	-32.2	-167.5	-62.7	-0.3	0	0	0	112.5	T312	T312-D316 WeakPolarHBondContact CG2-OD2 3.26Å; T312-D316 VanDerWaalsContact O-CB 3.31Å; T312-D316 WeakPolarHBondContact O-CB 3.32Å; T312-D316 PolarHBondContact O-N 3.3Å
317	I	66.9	Low	70.6	Confident	27 Å²	27	32.8 Å²	32.8	14%	0.138	18%	0.177	C	C	.	.	I	π-helix	trans	-99.2	-48.6	-179.2	-52.3	-62.3	0	0	0	111.6	Y313 N449	Y313-I317 HydrophobicContact CD2-CB 3.98Å; Y313-I317 HydrophobicContact CD2-CG1 3.67Å; Y313-I317 HydrophobicContact CD2-CG2 4.39Å; Y313-I317 HydrophobicContact CE2-CB 4.01Å; Y313-I317 HydrophobicContact CE2-CG1 4Å; Y313-I317 HydrophobicContact CE2-CG2 3.91Å; Y313-I317 VanDerWaalsContact O-CB 3.26Å; Y313-I317 WeakPolarHBondContact O-CB 3.39Å; Y313-I317 PolarHBondContact O-N 3.46Å; Y313-I317 VanDerWaalsContact O-N 3.09Å; I317-N449 HydrophobicContact CD1-CB 3.77Å; I317-N449 WeakPolarHBondContact CD1-O 3.47Å
318	L	66.4	Low	71	Confident	4 Å²	4	34.2 Å²	34.2	2%	0.021	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.2	-12.7	-176	-48.1	179.9	0	0	0	112.9	Y313 M314 F320 Y387 A390 V391	Y313-L318 HydrophobicContact CD1-CD1 4.1Å; Y313-L318 HydrophobicContact CD1-CG 4.28Å; Y313-L318 HydrophobicContact CE1-CD1 3.8Å; Y313-L318 HydrophobicContact CE1-CD2 4Å; Y313-L318 HydrophobicContact CE1-CG 3.97Å; Y313-L318 PolarHBondContact O-N 3.28Å; Y313-L318 VanDerWaalsContact O-N 3.16Å; M314-L318 HydrophobicContact CE-CD1 4.32Å; M314-L318 HydrophobicContact CG-CD1 4.42Å; M314-L318 CarbonylContact O-C 3.56Å; M314-L318 WeakPolarHBondContact O-CB 3.41Å; M314-L318 HydrophobicContact SD-CD1 3.5Å; M314-L318 WeakPolarHBondContact SD-CD1 3.4Å; L318-F320 VanDerWaalsContact C-N 3.33Å; L318-F320 HydrophobicContact CB-CD2 3.6Å; L318-F320 HydrophobicContact CB-CE2 3.58Å; L318-F320 HydrophobicContact CD1-CD2 4.17Å; L318-F320 HydrophobicContact CD1-CE2 3.75Å; L318-F320 HydrophobicContact CG-CE2 4.33Å; L318-F320 PolarHBondContact O-N 3.34Å; L318-Y387 HydrophobicContact CB-CD1 4.06Å; L318-Y387 HydrophobicContact CB-CG 4.35Å; L318-Y387 HydrophobicContact CD2-CD1 3.41Å; L318-Y387 VanDerWaalsContact CD2-CD1 3.41Å; L318-Y387 HydrophobicContact CD2-CE1 4.11Å; L318-Y387 HydrophobicContact CD2-CG 4.24Å; L318-Y387 HydrophobicContact CG-CD1 4.3Å; L318-A390 HydrophobicContact CD2-CB 4.43Å; L318-V391 HydrophobicContact CD1-CG2 4.21Å
319	G	65.3	Low	71.5	Confident	37 Å²	37	33.4 Å²	33.4	38%	0.381	18%	0.18	S	C	.	.			trans	70.9	21.9	174.4	0	0	0	0	0	114.8	M314 N315	M314-G319 PolarHBondContact O-N 2.76Å; N315-G319 WeakPolarHBondContact O-CA 3.33Å; N315-G319 PolarHBondContact O-N 3Å; N315-G319 VanDerWaalsContact O-N 3.14Å
320	F	71.3	Confident	72.2	Confident	23 Å²	23	32.9 Å²	32.9	10%	0.101	18%	0.178	C	C	.	.			trans	-75.2	142.2	178.4	-69.1	-61.5	0	0	0	111.6	M314 N315 L318 Q324 L328 V391	M314-F320 HydrophobicContact CB-CD2 4.4Å; M314-F320 PolarHBondContact O-N 3.42Å; M314-F320 HydrophobicContact SD-CD2 4.07Å; M314-F320 HydrophobicContact SD-CE2 4.2Å; N315-F320 PolarHBondContact OD1-O 3Å; L318-F320 VanDerWaalsContact C-N 3.33Å; L318-F320 HydrophobicContact CB-CD2 3.6Å; L318-F320 HydrophobicContact CB-CE2 3.58Å; L318-F320 HydrophobicContact CD1-CD2 4.17Å; L318-F320 HydrophobicContact CD1-CE2 3.75Å; L318-F320 HydrophobicContact CG-CE2 4.33Å; L318-F320 PolarHBondContact O-N 3.34Å; F320-Q324 HydrophobicContact CB-CB 4.14Å; F320-Q324 HydrophobicContact CD1-CB 4.43Å; F320-L328 HydrophobicContact CB-CD1 4.49Å; F320-L328 HydrophobicContact CD1-CD1 3.73Å; F320-L328 HydrophobicContact CD2-CD1 3.71Å; F320-L328 HydrophobicContact CE1-CD1 3.75Å; F320-L328 HydrophobicContact CE2-CD1 3.72Å; F320-L328 HydrophobicContact CG-CD1 3.72Å; F320-L328 HydrophobicContact CZ-CD1 3.75Å; F320-V391 HydrophobicContact CE2-CG2 4.11Å
321	S	69.5	Low	72.8	Confident	43 Å²	43	36.2 Å²	36.2	30%	0.301	20%	0.196	S	C	.	.			trans	-64.7	159.2	174.1	64.9	0	0	0	0	111.8	Q323 Q324 N325	S321-Q323 VanDerWaalsContact C-N 3.26Å; S321-Q323 PolarHBondContact O-N 3.35Å; S321-Q324 CarbonylContact O-C 3.53Å; S321-Q324 PolarHBondContact O-N 3.42Å; S321-Q324 WeakPolarHBondContact OG-CG 3.34Å; S321-Q324 PolarHBondContact OG-OE1 2.91Å; S321-N325 VanDerWaalsContact O-CB 3.32Å; S321-N325 WeakPolarHBondContact O-CB 3.42Å; S321-N325 PolarHBondContact O-N 2.71Å
322	I	64.5	Low	73.8	Confident	51 Å²	51	36 Å²	36	26%	0.262	19%	0.194	S	C	.	.	H	α-helix	trans	-53.9	-41.1	-178.4	-63.2	170.4	0	0	0	112.4	V62 N325 G326	V62-I322 HydrophobicContact CG1-CD1 3.98Å; V62-I322 HydrophobicContact CG1-CG1 3.98Å; I322-N325 WeakPolarHBondContact O-CB 3.36Å; I322-N325 PolarHBondContact O-N 2.91Å; I322-G326 PolarHBondContact O-N 3.21Å
323	Q	63.5	Low	74.6	Confident	62 Å²	62	34.3 Å²	34.3	29%	0.29	18%	0.183	S	C	.	.	H	α-helix	trans	-62.8	-51.2	176.4	-68.7	165.9	-10.7	0	0	111.1	F219 S321 N325 G326 F327	F219-Q323 VanDerWaalsContact CD1-NE2 3.32Å; F219-Q323 HydrophobicContact CD2-CG 4.43Å; F219-Q323 HydrophobicContact CG-CG 4.5Å; S321-Q323 VanDerWaalsContact C-N 3.26Å; S321-Q323 PolarHBondContact O-N 3.35Å; Q323-N325 VanDerWaalsContact C-N 3.27Å; Q323-N325 PolarHBondContact O-N 3.29Å; Q323-G326 PolarHBondContact O-N 3.35Å; Q323-F327 WeakPolarHBondContact O-CD2 3.42Å; Q323-F327 PolarHBondContact O-N 3.44Å
324	Q	72.4	Confident	75.5	Confident	77 Å²	77	36.9 Å²	36.9	36%	0.36	20%	0.198	S	C	.	.	H	α-helix	trans	-62.4	-37.2	177.4	-70.7	172.8	-19.1	0	0	111.5	F320 S321 F327 L328	F320-Q324 HydrophobicContact CB-CB 4.14Å; F320-Q324 HydrophobicContact CD1-CB 4.43Å; S321-Q324 CarbonylContact O-C 3.53Å; S321-Q324 PolarHBondContact O-N 3.42Å; S321-Q324 WeakPolarHBondContact OG-CG 3.34Å; S321-Q324 PolarHBondContact OG-OE1 2.91Å; Q324-F327 PolarHBondContact O-N 2.86Å; Q324-L328 HydrophobicContact CB-CD1 4.36Å; Q324-L328 VanDerWaalsContact O-CB 3.23Å; Q324-L328 WeakPolarHBondContact O-CB 3.28Å; Q324-L328 WeakPolarHBondContact O-CG 3.11Å; Q324-L328 PolarHBondContact O-N 2.84Å
325	N	72.6	Confident	76.3	Confident	8 Å²	8	37.5 Å²	37.5	4%	0.043	20%	0.204	C	C	.	.	H	α-helix	trans	-62.1	-45.5	177.4	-171.6	11.8	0	0	0	111.5	P311 M314 S321 I322 Q323 F327 S329	P311-N325 WeakPolarHBondContact CA-OD1 3.41Å; P311-N325 PolarHBondContact O-ND2 3.04Å; M314-N325 WeakPolarHBondContact CB-OD1 3.29Å; S321-N325 VanDerWaalsContact O-CB 3.32Å; S321-N325 WeakPolarHBondContact O-CB 3.42Å; S321-N325 PolarHBondContact O-N 2.71Å; I322-N325 WeakPolarHBondContact O-CB 3.36Å; I322-N325 PolarHBondContact O-N 2.91Å; Q323-N325 VanDerWaalsContact C-N 3.27Å; Q323-N325 PolarHBondContact O-N 3.29Å; N325-F327 PolarHBondContact O-N 3.22Å; N325-S329 WeakPolarHBondContact O-CB 3.3Å; N325-S329 PolarHBondContact O-N 3.34Å; N325-S329 PolarHBondContact O-OG 2.88Å; N325-S329 PolarHBondContact OD1-OG 2.78Å
326	G	73.3	Confident	77.4	Confident	3 Å²	3	35.5 Å²	35.5	3%	0.031	19%	0.194	C	C	.	.	H	α-helix	trans	-57.3	-47.8	175.3	0	0	0	0	0	112.7	I322 Q323 A330	I322-G326 PolarHBondContact O-N 3.21Å; Q323-G326 PolarHBondContact O-N 3.35Å; G326-A330 PolarHBondContact O-N 3.25Å
327	F	82.2	Confident	78.4	Confident	130 Å²	130	32.6 Å²	32.6	57%	0.57	18%	0.179	S	C	*	.	H	α-helix	trans	-69.3	-47.3	178.4	-81.6	-80.5	0	0	0	113.5	P212 Q323 Q324 N325 A330	P212-F327 HydrophobicContact CB-CD1 4.1Å; P212-F327 HydrophobicContact CB-CD2 4.43Å; P212-F327 HydrophobicContact CB-CE1 4.09Å; P212-F327 HydrophobicContact CB-CE2 4.41Å; P212-F327 HydrophobicContact CB-CG 4.27Å; P212-F327 HydrophobicContact CB-CZ 4.25Å; P212-F327 HydrophobicContact CG-CD1 4.4Å; Q323-F327 WeakPolarHBondContact O-CD2 3.42Å; Q323-F327 PolarHBondContact O-N 3.44Å; Q324-F327 PolarHBondContact O-N 2.86Å; N325-F327 PolarHBondContact O-N 3.22Å; F327-A330 WeakPolarHBondContact O-CB 3.48Å; F327-A330 PolarHBondContact O-N 2.64Å
328	L	81.6	Confident	79.6	Confident	42 Å²	42	36.3 Å²	36.3	22%	0.22	20%	0.199	C	C	.	.	H	α-helix	trans	-69.2	-35.3	-177.5	-68.3	172.6	0	0	0	111.8	M314 F320 Q324 A330 L331 P332 V391	M314-L328 HydrophobicContact SD-CB 4.41Å; F320-L328 HydrophobicContact CB-CD1 4.49Å; F320-L328 HydrophobicContact CD1-CD1 3.73Å; F320-L328 HydrophobicContact CD2-CD1 3.71Å; F320-L328 HydrophobicContact CE1-CD1 3.75Å; F320-L328 HydrophobicContact CE2-CD1 3.72Å; F320-L328 HydrophobicContact CG-CD1 3.72Å; F320-L328 HydrophobicContact CZ-CD1 3.75Å; Q324-L328 HydrophobicContact CB-CD1 4.36Å; Q324-L328 VanDerWaalsContact O-CB 3.23Å; Q324-L328 WeakPolarHBondContact O-CB 3.28Å; Q324-L328 WeakPolarHBondContact O-CG 3.11Å; Q324-L328 PolarHBondContact O-N 2.84Å; L328-A330 PolarHBondContact O-N 3.31Å; L328-L331 HydrophobicContact CD2-CD1 4Å; L328-L331 PolarHBondContact O-N 3.37Å; L328-P332 WeakPolarHBondContact O-CD 3.37Å; L328-V391 HydrophobicContact CD2-CG1 4.39Å
329	S	82.7	Confident	80.8	Confident	3 Å²	3	39.1 Å²	39.1	2%	0.021	21%	0.212	C	C	.	.	H	α-helix	trans	-68	-20.2	174.8	-68.7	0	0	0	0	113	N325 P332 Y333	N325-S329 WeakPolarHBondContact O-CB 3.3Å; N325-S329 PolarHBondContact O-N 3.34Å; N325-S329 PolarHBondContact O-OG 2.88Å; N325-S329 PolarHBondContact OD1-OG 2.78Å; S329-P332 WeakPolarHBondContact O-CD 3.07Å; S329-Y333 WeakPolarHBondContact O-CD2 3.45Å; S329-Y333 WeakPolarHBondContact O-CE2 3.38Å
330	A	85.4	Confident	81.9	Confident	8 Å²	8	38.1 Å²	38.1	7%	0.066	20%	0.2	C	C	.	.	H	α-helix	trans	-77.6	-26.1	176.3	0	0	0	0	0	113.4	P212 G326 F327 L328 Y333 L334	P212-A330 HydrophobicContact CG-CB 3.75Å; G326-A330 PolarHBondContact O-N 3.25Å; F327-A330 WeakPolarHBondContact O-CB 3.48Å; F327-A330 PolarHBondContact O-N 2.64Å; L328-A330 PolarHBondContact O-N 3.31Å; A330-Y333 PolarHBondContact O-N 2.81Å; A330-L334 PolarHBondContact O-N 2.94Å
331	L	88.9	Confident	82.7	Confident	74 Å²	74	39.4 Å²	39.4	39%	0.387	21%	0.21	S	C	.	.	H	α-helix	trans	-58.1	-45.9	-174.7	-67.3	173.3	0	0	0	113.9	L328 Y333 L334 G335 V391 T395	L328-L331 HydrophobicContact CD2-CD1 4Å; L328-L331 PolarHBondContact O-N 3.37Å; L331-Y333 VanDerWaalsContact C-N 3.32Å; L331-Y333 PolarHBondContact O-N 3.01Å; L331-L334 PolarHBondContact O-N 3.3Å; L331-G335 PolarHBondContact O-N 3.07Å; L331-V391 HydrophobicContact CD1-CG1 4.27Å; L331-T395 HydrophobicContact CB-CG2 4.31Å
332	P	89.1	Confident	83.7	Confident	0 Å²	0	42 Å²	42	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-61.9	-38	179.5	-22.9	35.2	0	0	0	113.2	L310 L328 S329 G335 C336 S398	L310-P332 HydrophobicContact CD2-CG 4.01Å; L328-P332 WeakPolarHBondContact O-CD 3.37Å; S329-P332 WeakPolarHBondContact O-CD 3.07Å; P332-G335 PolarHBondContact O-N 3.35Å; P332-C336 WeakPolarHBondContact O-CB 3.32Å; P332-C336 PolarHBondContact O-N 3.2Å; P332-S398 WeakPolarHBondContact CB-OG 3.36Å; P332-S398 VanDerWaalsContact O-CB 3.28Å; P332-S398 WeakPolarHBondContact O-CB 3.44Å
333	Y	88.7	Confident	85	Confident	4 Å²	4	39.8 Å²	39.8	2%	0.016	21%	0.209	C	C	.	.	H	α-helix	trans	-72.1	-34.7	178.1	-56.1	-69.9	0	0	0	112.3	T207 L211 F303 L306 L307 L310 S329 A330 L331 C336 A337	T207-Y333 HydrophobicContact CG2-CD1 4.04Å; T207-Y333 HydrophobicContact CG2-CD2 3.67Å; T207-Y333 HydrophobicContact CG2-CE1 4.47Å; T207-Y333 HydrophobicContact CG2-CE2 4.13Å; T207-Y333 HydrophobicContact CG2-CG 3.65Å; L211-Y333 HydrophobicContact CD1-CD2 3.87Å; L211-Y333 HydrophobicContact CD1-CE2 3.83Å; F303-Y333 HydrophobicContact CD2-CE1 4.45Å; F303-Y333 AromaticContact CE2-CD1 3.99Å; F303-Y333 HydrophobicContact CE2-CD1 3.99Å; F303-Y333 AromaticContact CE2-CE1 3.82Å; F303-Y333 HydrophobicContact CE2-CE1 3.82Å; F303-Y333 HydrophobicContact CZ-CE1 4.33Å; L306-Y333 VanDerWaalsContact C-OH 3.3Å; L306-Y333 PolarHBondContact O-OH 3.18Å; L307-Y333 WeakPolarHBondContact CA-OH 3.44Å; L307-Y333 HydrophobicContact CD1-CE1 3.79Å; L307-Y333 HydrophobicContact CD1-CE2 4.34Å; L307-Y333 PolarHBondContact N-OH 3.37Å; L307-Y333 VanDerWaalsContact N-OH 3.15Å; L310-Y333 HydrophobicContact CD2-CE2 4.4Å; S329-Y333 WeakPolarHBondContact O-CD2 3.45Å; S329-Y333 WeakPolarHBondContact O-CE2 3.38Å; A330-Y333 PolarHBondContact O-N 2.81Å; L331-Y333 VanDerWaalsContact C-N 3.32Å; L331-Y333 PolarHBondContact O-N 3.01Å; Y333-C336 WeakPolarHBondContact O-CB 3.37Å; Y333-C336 PolarHBondContact O-N 3.37Å; Y333-A337 PolarHBondContact O-N 3.22Å
334	L	90.9	Very high	86	Confident	67 Å²	67	37 Å²	37	35%	0.351	20%	0.197	S	C	.	.	H	α-helix	trans	-63.9	-47	173	178.3	61.9	0	0	0	110.7	V208 A330 L331 C336 A337 L338	V208-L334 HydrophobicContact CG1-CB 4.25Å; V208-L334 HydrophobicContact CG1-CD1 4.34Å; V208-L334 HydrophobicContact CG2-CB 3.87Å; V208-L334 VanDerWaalsContact CG2-N 3.28Å; A330-L334 PolarHBondContact O-N 2.94Å; L331-L334 PolarHBondContact O-N 3.3Å; L334-C336 VanDerWaalsContact C-N 3.29Å; L334-C336 PolarHBondContact O-N 3.29Å; L334-A337 WeakPolarHBondContact O-CB 3.19Å; L334-A337 PolarHBondContact O-N 2.99Å; L334-L338 HydrophobicContact CD1-CD1 4.36Å; L334-L338 HydrophobicContact CD1-CG 4.38Å; L334-L338 HydrophobicContact CG-CD1 4.26Å; L334-L338 WeakPolarHBondContact O-CG 3.43Å; L334-L338 PolarHBondContact O-N 3.44Å
335	G	90.4	Very high	86.7	Confident	13 Å²	13	38.8 Å²	38.8	13%	0.134	21%	0.206	C	C	.	.	H	α-helix	trans	-57.8	-42.7	174.1	0	0	0	0	0	112.1	L331 P332 L338 M339	L331-G335 PolarHBondContact O-N 3.07Å; P332-G335 PolarHBondContact O-N 3.35Å; G335-L338 PolarHBondContact O-N 3.32Å; G335-M339 WeakPolarHBondContact O-CB 3.46Å; G335-M339 PolarHBondContact O-N 3.43Å
336	C	91.2	Very high	87.5	Confident	5 Å²	5	41.8 Å²	41.8	3%	0.034	22%	0.224	C	C	.	.	H	α-helix	trans	-59.3	-47.2	175.5	-167	0	0	0	0	112	P332 Y333 L334 M339 A340 S398 G402	P332-C336 WeakPolarHBondContact O-CB 3.32Å; P332-C336 PolarHBondContact O-N 3.2Å; Y333-C336 WeakPolarHBondContact O-CB 3.37Å; Y333-C336 PolarHBondContact O-N 3.37Å; L334-C336 VanDerWaalsContact C-N 3.29Å; L334-C336 PolarHBondContact O-N 3.29Å; C336-M339 PolarHBondContact O-N 2.91Å; C336-A340 VanDerWaalsContact O-CB 3.3Å; C336-A340 WeakPolarHBondContact O-CB 3.41Å; C336-A340 PolarHBondContact O-N 3.42Å; C336-S398 WeakPolarHBondContact CB-O 3.49Å; C336-S398 PolarHBondContact SG-O 2.95Å; C336-S398 VanDerWaalsContact SG-O 3.38Å; C336-G402 VanDerWaalsContact SG-CA 3.58Å
337	A	89.3	Confident	88.1	Confident	4 Å²	4	41.7 Å²	41.7	3%	0.033	22%	0.223	C	C	.	.	H	α-helix	trans	-60	-48.7	179.1	0	0	0	0	0	112.1	I201 Q204 Y333 L334 A340 V341	I201-A337 HydrophobicContact CG1-CB 4.36Å; Q204-A337 HydrophobicContact CB-CB 3.77Å; Q204-A337 HydrophobicContact CG-CB 4.42Å; Y333-A337 PolarHBondContact O-N 3.22Å; L334-A337 WeakPolarHBondContact O-CB 3.19Å; L334-A337 PolarHBondContact O-N 2.99Å; A337-A340 PolarHBondContact O-N 3.18Å; A337-V341 PolarHBondContact O-N 3.21Å; A337-V341 VanDerWaalsContact O-N 3.17Å
338	L	91.6	Very high	88.1	Confident	105 Å²	105	36.6 Å²	36.6	55%	0.55	20%	0.202	S	C	.	.	H	α-helix	trans	-62.4	-47.4	-179	-67.8	174.1	0	0	0	111.1	L334 G335 A340 V341 L342	L334-L338 HydrophobicContact CD1-CD1 4.36Å; L334-L338 HydrophobicContact CD1-CG 4.38Å; L334-L338 HydrophobicContact CG-CD1 4.26Å; L334-L338 WeakPolarHBondContact O-CG 3.43Å; L334-L338 PolarHBondContact O-N 3.44Å; G335-L338 PolarHBondContact O-N 3.32Å; L338-A340 VanDerWaalsContact C-N 3.34Å; L338-A340 PolarHBondContact O-N 3.17Å; L338-V341 PolarHBondContact O-N 3.26Å; L338-L342 WeakPolarHBondContact O-CG 3.41Å; L338-L342 PolarHBondContact O-N 3.11Å
339	M	92.5	Very high	88.1	Confident	63 Å²	63	40.1 Å²	40.1	31%	0.31	21%	0.213	S	C	.	.	H	α-helix	trans	-69.1	-31.1	178.6	-74.8	-50.5	-65.9	0	0	113.2	G335 C336 L342 S343 A399 V403	G335-M339 WeakPolarHBondContact O-CB 3.46Å; G335-M339 PolarHBondContact O-N 3.43Å; C336-M339 PolarHBondContact O-N 2.91Å; M339-L342 PolarHBondContact O-N 3.39Å; M339-L342 HydrophobicContact SD-CD1 3.82Å; M339-S343 WeakPolarHBondContact O-CB 3.33Å; M339-S343 PolarHBondContact O-N 3.04Å; M339-S343 PolarHBondContact O-OG 3.16Å; M339-A399 WeakPolarHBondContact CB-O 3.17Å; M339-A399 HydrophobicContact CG-CB 4Å; M339-A399 WeakPolarHBondContact CG-O 3.35Å; M339-V403 HydrophobicContact CE-CG2 4.17Å
340	A	89.1	Confident	88.2	Confident	15 Å²	15	41.7 Å²	41.7	12%	0.124	22%	0.221	C	C	.	.	H	α-helix	trans	-60.6	-46.9	172.9	0	0	0	0	0	111.3	C336 A337 L338 S343 G344 G402 A405	C336-A340 VanDerWaalsContact O-CB 3.3Å; C336-A340 WeakPolarHBondContact O-CB 3.41Å; C336-A340 PolarHBondContact O-N 3.42Å; A337-A340 PolarHBondContact O-N 3.18Å; L338-A340 VanDerWaalsContact C-N 3.34Å; L338-A340 PolarHBondContact O-N 3.17Å; A340-S343 PolarHBondContact O-N 3.33Å; A340-S343 PolarHBondContact O-OG 2.88Å; A340-G344 PolarHBondContact O-N 3.33Å; A340-G344 VanDerWaalsContact O-N 3.11Å; A340-G402 WeakPolarHBondContact CA-O 3.12Å; A340-A405 HydrophobicContact CB-CB 3.88Å
341	V	87.9	Confident	88.1	Confident	50 Å²	50	44.6 Å²	44.6	30%	0.303	23%	0.23	S	C	.	.	H	α-helix	trans	-62.5	-50	176.5	176.4	0	0	0	0	111.5	I201 A337 L338 S343 G344 Q345	I201-V341 HydrophobicContact CD1-CG2 3.25Å; I201-V341 HydrophobicContact CG1-CG2 4.09Å; A337-V341 PolarHBondContact O-N 3.21Å; A337-V341 VanDerWaalsContact O-N 3.17Å; L338-V341 PolarHBondContact O-N 3.26Å; V341-S343 VanDerWaalsContact C-N 3.29Å; V341-S343 PolarHBondContact O-N 3.03Å; V341-G344 PolarHBondContact O-N 3.49Å; V341-G344 VanDerWaalsContact O-N 3.11Å; V341-Q345 PolarHBondContact O-N 2.91Å
342	L	90.8	Very high	87.6	Confident	97 Å²	97	46.8 Å²	46.8	51%	0.508	24%	0.238	S	C	.	.	H	α-helix	trans	-59.6	-43	179.9	-69.5	173.3	0	0	0	111.1	L338 M339 G344 Q345 V346	L338-L342 WeakPolarHBondContact O-CG 3.41Å; L338-L342 PolarHBondContact O-N 3.11Å; M339-L342 PolarHBondContact O-N 3.39Å; M339-L342 HydrophobicContact SD-CD1 3.82Å; L342-G344 VanDerWaalsContact C-N 3.27Å; L342-G344 PolarHBondContact O-N 3.26Å; L342-Q345 PolarHBondContact O-N 2.83Å; L342-V346 WeakPolarHBondContact O-CG2 3.27Å; L342-V346 PolarHBondContact O-N 3.36Å
343	S	90.4	Very high	87	Confident	5 Å²	5	50.9 Å²	50.9	4%	0.035	26%	0.264	C	S	.	.	H	α-helix	trans	-60.3	-37.6	177.2	78.8	0	0	0	0	112.1	M339 A340 V341 V346 A347 F365 S406	M339-S343 WeakPolarHBondContact O-CB 3.33Å; M339-S343 PolarHBondContact O-N 3.04Å; M339-S343 PolarHBondContact O-OG 3.16Å; A340-S343 PolarHBondContact O-N 3.33Å; A340-S343 PolarHBondContact O-OG 2.88Å; V341-S343 VanDerWaalsContact C-N 3.29Å; V341-S343 PolarHBondContact O-N 3.03Å; S343-V346 PolarHBondContact O-N 3.44Å; S343-A347 VanDerWaalsContact O-CB 3.24Å; S343-A347 WeakPolarHBondContact O-CB 3.43Å; S343-A347 PolarHBondContact O-N 3.14Å; S343-F365 VanDerWaalsContact O-CE1 3.25Å; S343-F365 WeakPolarHBondContact O-CE1 3Å; S343-S406 PolarHBondContact O-OG 3.38Å; S343-S406 PolarHBondContact OG-OG 3.16Å
344	G	85.8	Confident	86.5	Confident	5 Å²	5	58 Å²	58	5%	0.052	29%	0.29	C	S	.	.	H	α-helix	trans	-62.4	-47.7	177.2	0	0	0	0	0	111.9	A340 V341 L342 V346 A347 D348 S406	A340-G344 PolarHBondContact O-N 3.33Å; A340-G344 VanDerWaalsContact O-N 3.11Å; V341-G344 PolarHBondContact O-N 3.49Å; V341-G344 VanDerWaalsContact O-N 3.11Å; L342-G344 VanDerWaalsContact C-N 3.27Å; L342-G344 PolarHBondContact O-N 3.26Å; G344-V346 PolarHBondContact O-N 3.15Å; G344-A347 PolarHBondContact O-N 3.31Å; G344-D348 PolarHBondContact O-N 3Å; G344-S406 WeakPolarHBondContact CA-OG 2.82Å; G344-S406 PolarHBondContact N-OG 3.3Å
345	Q	86.8	Confident	86	Confident	114 Å²	114	61 Å²	61	53%	0.533	31%	0.306	S	S	.	.	H	α-helix	trans	-62.2	-43.2	178.3	-58.9	-58.2	-36.3	0	0	111.8	V341 L342 Y349	V341-Q345 PolarHBondContact O-N 2.91Å; L342-Q345 PolarHBondContact O-N 2.83Å; Q345-Y349 WeakPolarHBondContact O-CB 3.38Å; Q345-Y349 PolarHBondContact O-N 3.21Å
346	V	88.6	Confident	85.8	Confident	71 Å²	71	65.9 Å²	65.9	43%	0.43	32%	0.321	S	S	.	.	H	α-helix	trans	-66.5	-42.2	177.5	-179.7	0	0	0	0	110.7	L342 S343 G344 D348 Y349 L350 F365	L342-V346 WeakPolarHBondContact O-CG2 3.27Å; L342-V346 PolarHBondContact O-N 3.36Å; S343-V346 PolarHBondContact O-N 3.44Å; G344-V346 PolarHBondContact O-N 3.15Å; V346-D348 PolarHBondContact O-N 3.21Å; V346-Y349 PolarHBondContact O-N 3.17Å; V346-L350 HydrophobicContact CG1-CD1 3.98Å; V346-L350 HydrophobicContact CG1-CG 4.2Å; V346-L350 WeakPolarHBondContact O-CB 3.25Å; V346-L350 VanDerWaalsContact O-CG 3.23Å; V346-L350 WeakPolarHBondContact O-CG 3.48Å; V346-L350 PolarHBondContact O-N 3.15Å; V346-F365 HydrophobicContact CB-CZ 4.21Å; V346-F365 HydrophobicContact CG1-CZ 3.94Å
347	A	86	Confident	85.6	Confident	1 Å²	1	69 Å²	69	1%	0.008	34%	0.343	C	S	.	.	H	α-helix	trans	-61.7	-43	178.6	0	0	0	0	0	111.9	S343 G344 L350 R351 V361 F365	S343-A347 VanDerWaalsContact O-CB 3.24Å; S343-A347 WeakPolarHBondContact O-CB 3.43Å; S343-A347 PolarHBondContact O-N 3.14Å; G344-A347 PolarHBondContact O-N 3.31Å; A347-L350 PolarHBondContact O-N 3.25Å; A347-R351 VanDerWaalsContact O-CG 3.28Å; A347-R351 WeakPolarHBondContact O-CG 3.15Å; A347-R351 PolarHBondContact O-N 3.44Å; A347-R351 VanDerWaalsContact O-N 3.16Å; A347-V361 HydrophobicContact CB-CG1 3.86Å; A347-F365 HydrophobicContact CB-CE1 3.96Å; A347-F365 HydrophobicContact CB-CZ 3.99Å
348	D	82.7	Confident	85.4	Confident	23 Å²	23	70.4 Å²	70.4	12%	0.123	35%	0.352	C	S	.	.	H	α-helix	trans	-66.6	-44.9	177	-69	-19.3	0	0	0	110.8	S193 G344 V346 L350 R351 E352	S193-D348 PolarHBondContact OG-OD1 2.99Å; S193-D348 PolarHBondContact OG-OD2 3.02Å; G344-D348 PolarHBondContact O-N 3Å; V346-D348 PolarHBondContact O-N 3.21Å; D348-L350 VanDerWaalsContact C-N 3.34Å; D348-L350 PolarHBondContact O-N 3.2Å; D348-R351 PolarHBondContact O-N 3.38Å; D348-R351 VanDerWaalsContact O-N 3.15Å; D348-E352 WeakPolarHBondContact O-CB 3.42Å; D348-E352 WeakPolarHBondContact O-CG 3.41Å; D348-E352 PolarHBondContact O-N 3.43Å
349	Y	81.4	Confident	85.3	Confident	116 Å²	116	67.1 Å²	67.1	46%	0.455	34%	0.336	S	S	.	.	H	α-helix	trans	-58.2	-42.1	175.3	174.9	-102.1	0	0	0	113.2	Q345 V346 R351 T353 R354	Q345-Y349 WeakPolarHBondContact O-CB 3.38Å; Q345-Y349 PolarHBondContact O-N 3.21Å; V346-Y349 PolarHBondContact O-N 3.17Å; Y349-R351 VanDerWaalsContact C-N 3.32Å; Y349-R351 PolarHBondContact O-N 2.75Å; Y349-T353 HydrophobicContact CD2-CG2 4.44Å; Y349-T353 WeakPolarHBondContact CD2-OG1 3.3Å; Y349-T353 HydrophobicContact CE2-CG2 3.77Å; Y349-T353 VanDerWaalsContact O-CB 3.3Å; Y349-T353 WeakPolarHBondContact O-CB 3.5Å; Y349-T353 PolarHBondContact O-N 3.28Å; Y349-R354 HydrophobicContact CE1-CG 4.21Å; Y349-R354 PolarHBondContact O-N 3.31Å
350	L	85.8	Confident	85.3	Confident	36 Å²	36	69.2 Å²	69.2	19%	0.188	34%	0.343	C	S	.	.	H	α-helix	trans	-66.2	-33.5	178.3	-73	177.9	0	0	0	112.5	V346 A347 D348 R354 L355 Y356 V361 F365	V346-L350 HydrophobicContact CG1-CD1 3.98Å; V346-L350 HydrophobicContact CG1-CG 4.2Å; V346-L350 WeakPolarHBondContact O-CB 3.25Å; V346-L350 VanDerWaalsContact O-CG 3.23Å; V346-L350 WeakPolarHBondContact O-CG 3.48Å; V346-L350 PolarHBondContact O-N 3.15Å; A347-L350 PolarHBondContact O-N 3.25Å; D348-L350 VanDerWaalsContact C-N 3.34Å; D348-L350 PolarHBondContact O-N 3.2Å; L350-R354 HydrophobicContact CD2-CB 4.44Å; L350-R354 HydrophobicContact CD2-CG 4.18Å; L350-R354 CarbonylContact O-C 3.38Å; L350-R354 WeakPolarHBondContact O-CB 3.38Å; L350-L355 PolarHBondContact O-N 3.11Å; L350-Y356 HydrophobicContact CB-CD2 4.06Å; L350-Y356 HydrophobicContact CD2-CD2 3.9Å; L350-Y356 HydrophobicContact CD2-CE2 3.81Å; L350-Y356 HydrophobicContact CG-CD2 4.37Å; L350-Y356 PolarHBondContact O-N 3.46Å; L350-Y356 VanDerWaalsContact O-N 3.09Å; L350-V361 HydrophobicContact CB-CG2 4.22Å; L350-F365 HydrophobicContact CD1-CE2 3.83Å; L350-F365 HydrophobicContact CD1-CZ 4.08Å
351	R	82.8	Confident	85.4	Confident	69 Å²	69	68.6 Å²	68.6	26%	0.26	34%	0.338	S	S	.	.	H	α-helix	trans	-81.7	-43.4	179.5	-68.3	171.4	70.7	-145.2	5.1	112	A347 D348 Y349 L355 T358 V361	A347-R351 VanDerWaalsContact O-CG 3.28Å; A347-R351 WeakPolarHBondContact O-CG 3.15Å; A347-R351 PolarHBondContact O-N 3.44Å; A347-R351 VanDerWaalsContact O-N 3.16Å; D348-R351 PolarHBondContact O-N 3.38Å; D348-R351 VanDerWaalsContact O-N 3.15Å; Y349-R351 VanDerWaalsContact C-N 3.32Å; Y349-R351 PolarHBondContact O-N 2.75Å; R351-L355 WeakPolarHBondContact O-CA 3.41Å; R351-T358 PolarHBondContact NH2-OG1 2.84Å; R351-V361 HydrophobicContact CG-CB 4.36Å; R351-V361 HydrophobicContact CG-CG1 4.47Å; R351-V361 HydrophobicContact CG-CG2 3.9Å
352	E	76.9	Confident	85.5	Confident	120 Å²	120	66.4 Å²	66.4	56%	0.561	32%	0.324	S	S	*	.	H	α-helix	trans	-80	-46.2	-175.2	-66.8	-168	157.2	0	0	112.8	D348	D348-E352 WeakPolarHBondContact O-CB 3.42Å; D348-E352 WeakPolarHBondContact O-CG 3.41Å; D348-E352 PolarHBondContact O-N 3.43Å
353	T	78.3	Confident	85.7	Confident	86 Å²	86	63.9 Å²	63.9	53%	0.528	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.1	-42	-173	-50.2	0	0	0	0	112.1	Y349	Y349-T353 HydrophobicContact CD2-CG2 4.44Å; Y349-T353 WeakPolarHBondContact CD2-OG1 3.3Å; Y349-T353 HydrophobicContact CE2-CG2 3.77Å; Y349-T353 VanDerWaalsContact O-CB 3.3Å; Y349-T353 WeakPolarHBondContact O-CB 3.5Å; Y349-T353 PolarHBondContact O-N 3.28Å
354	R	76.4	Confident	85.9	Confident	153 Å²	153	65.3 Å²	65.3	58%	0.577	32%	0.319	S	S	*	.	S	Bend	trans	-91.9	-4.5	-177.7	-62	-63.6	-153.1	174.8	4.6	113.7	Y349 L350 Y356	Y349-R354 HydrophobicContact CE1-CG 4.21Å; Y349-R354 PolarHBondContact O-N 3.31Å; L350-R354 HydrophobicContact CD2-CB 4.44Å; L350-R354 HydrophobicContact CD2-CG 4.18Å; L350-R354 CarbonylContact O-C 3.38Å; L350-R354 WeakPolarHBondContact O-CB 3.38Å; R354-Y356 HydrophobicContact CB-CD2 4.45Å; R354-Y356 HydrophobicContact CB-CE2 4.47Å; R354-Y356 PolarHBondContact O-N 3.34Å
355	L	82.1	Confident	86.3	Confident	130 Å²	130	66 Å²	66	68%	0.681	32%	0.32	S	S	*	.			trans	55.5	30.9	177	-58.5	171.6	0	0	0	113.8	L350 R351	L350-L355 PolarHBondContact O-N 3.11Å; R351-L355 WeakPolarHBondContact O-CA 3.41Å
356	Y	86.1	Confident	86.7	Confident	115 Å²	115	60.5 Å²	60.5	45%	0.451	30%	0.295	S	S	.	.			trans	-70.3	144.3	172.6	-71.4	-23.4	0	0	0	111.6	L350 R354 F360	L350-Y356 HydrophobicContact CB-CD2 4.06Å; L350-Y356 HydrophobicContact CD2-CD2 3.9Å; L350-Y356 HydrophobicContact CD2-CE2 3.81Å; L350-Y356 HydrophobicContact CG-CD2 4.37Å; L350-Y356 PolarHBondContact O-N 3.46Å; L350-Y356 VanDerWaalsContact O-N 3.09Å; R354-Y356 HydrophobicContact CB-CD2 4.45Å; R354-Y356 HydrophobicContact CB-CE2 4.47Å; R354-Y356 PolarHBondContact O-N 3.34Å; Y356-F360 HydrophobicContact CD2-CD1 4.19Å; Y356-F360 HydrophobicContact CD2-CE1 4.1Å; Y356-F360 HydrophobicContact CE2-CE1 4.27Å; Y356-F360 HydrophobicContact CG-CD1 4.23Å; Y356-F360 HydrophobicContact CG-CE1 4.47Å
357	S	86.9	Confident	87.1	Confident	72 Å²	72	59.6 Å²	59.6	50%	0.503	29%	0.288	S	S	.	.			trans	-64.2	144.8	178	70.2	0	0	0	0	111.2	V359 F360 V361	S357-V359 PolarHBondContact O-N 3.43Å; S357-F360 PolarHBondContact O-N 2.82Å; S357-F360 VanDerWaalsContact O-N 3.15Å; S357-F360 WeakPolarHBondContact OG-CB 3.33Å; S357-F360 PolarHBondContact OG-N 3.01Å; S357-V361 PolarHBondContact O-N 3.46Å
358	T	84.8	Confident	87.6	Confident	33 Å²	33	63.9 Å²	63.9	20%	0.202	31%	0.309	C	S	.	.	H	α-helix	trans	-53.8	-44.6	177.5	-55.1	0	0	0	0	110.7	R351 F360 V361 R362	R351-T358 PolarHBondContact NH2-OG1 2.84Å; T358-F360 VanDerWaalsContact C-N 3.35Å; T358-F360 PolarHBondContact O-N 3.35Å; T358-V361 PolarHBondContact O-N 3.4Å; T358-R362 HydrophobicContact CG2-CG 3.95Å; T358-R362 WeakPolarHBondContact O-CB 3.17Å; T358-R362 WeakPolarHBondContact O-CG 3.37Å; T358-R362 PolarHBondContact O-N 2.68Å
359	V	89.3	Confident	88.1	Confident	36 Å²	36	62.8 Å²	62.8	22%	0.218	30%	0.303	C	S	.	.	H	α-helix	trans	-58.5	-45.2	-179.5	-171.3	0	0	0	0	112	S357 R362 K363	S357-V359 PolarHBondContact O-N 3.43Å; V359-R362 PolarHBondContact O-N 2.63Å; V359-K363 HydrophobicContact CG1-CD 3.98Å; V359-K363 HydrophobicContact CG1-CG 4.38Å; V359-K363 WeakPolarHBondContact O-CB 3.07Å; V359-K363 WeakPolarHBondContact O-CG 3.32Å; V359-K363 PolarHBondContact O-N 3.48Å
360	F	91.8	Very high	88.8	Confident	107 Å²	107	57.3 Å²	57.3	47%	0.469	28%	0.282	S	S	.	.	H	α-helix	trans	-62.2	-48.7	-180	177.9	-100.2	0	0	0	111.3	Y356 S357 T358 R362 K363 S364	Y356-F360 HydrophobicContact CD2-CD1 4.19Å; Y356-F360 HydrophobicContact CD2-CE1 4.1Å; Y356-F360 HydrophobicContact CE2-CE1 4.27Å; Y356-F360 HydrophobicContact CG-CD1 4.23Å; Y356-F360 HydrophobicContact CG-CE1 4.47Å; S357-F360 PolarHBondContact O-N 2.82Å; S357-F360 VanDerWaalsContact O-N 3.15Å; S357-F360 WeakPolarHBondContact OG-CB 3.33Å; S357-F360 PolarHBondContact OG-N 3.01Å; T358-F360 VanDerWaalsContact C-N 3.35Å; T358-F360 PolarHBondContact O-N 3.35Å; F360-R362 PolarHBondContact O-N 3.46Å; F360-K363 PolarHBondContact O-N 3.04Å; F360-S364 WeakPolarHBondContact O-CB 3.25Å; F360-S364 PolarHBondContact O-N 2.97Å; F360-S364 PolarHBondContact O-OG 2.92Å
361	V	91.1	Very high	89.3	Confident	2 Å²	2	58.4 Å²	58.4	1%	0.012	29%	0.287	C	S	.	.	H	α-helix	trans	-61.2	-47.9	179.1	176.9	0	0	0	0	110.9	A347 L350 R351 S357 T358 K363 S364 F365	A347-V361 HydrophobicContact CB-CG1 3.86Å; L350-V361 HydrophobicContact CB-CG2 4.22Å; R351-V361 HydrophobicContact CG-CB 4.36Å; R351-V361 HydrophobicContact CG-CG1 4.47Å; R351-V361 HydrophobicContact CG-CG2 3.9Å; S357-V361 PolarHBondContact O-N 3.46Å; T358-V361 PolarHBondContact O-N 3.4Å; V361-K363 PolarHBondContact O-N 3.03Å; V361-S364 PolarHBondContact O-N 3.14Å; V361-F365 HydrophobicContact CG1-CD2 3.91Å; V361-F365 HydrophobicContact CG1-CE2 3.83Å; V361-F365 HydrophobicContact CG1-CZ 4.49Å; V361-F365 WeakPolarHBondContact O-CB 3.38Å; V361-F365 WeakPolarHBondContact O-CD2 3.43Å; V361-F365 PolarHBondContact O-N 2.97Å
362	R	91.4	Very high	89.9	Confident	4 Å²	4	55.8 Å²	55.8	2%	0.015	28%	0.282	C	S	.	.	H	α-helix	trans	-61	-41.6	-179.7	-63.4	-63.6	-176.7	-145.5	0.3	112.5	T358 V359 F360 S366 S406 G407 I410 D414	T358-R362 HydrophobicContact CG2-CG 3.95Å; T358-R362 WeakPolarHBondContact O-CB 3.17Å; T358-R362 WeakPolarHBondContact O-CG 3.37Å; T358-R362 PolarHBondContact O-N 2.68Å; V359-R362 PolarHBondContact O-N 2.63Å; F360-R362 PolarHBondContact O-N 3.46Å; R362-S366 WeakPolarHBondContact O-CB 3.3Å; R362-S366 PolarHBondContact O-N 3.05Å; R362-S366 PolarHBondContact O-OG 2.98Å; R362-S406 WeakPolarHBondContact CD-O 3.22Å; R362-S406 PolarHBondContact NH1-O 3.04Å; R362-G407 VanDerWaalsContact CD-O 3.22Å; R362-G407 WeakPolarHBondContact CD-O 3.36Å; R362-I410 VanDerWaalsContact NH2-CG2 3.3Å; R362-D414 IonicContact CZ-OD2 3.37Å; R362-D414 IonicContact NE-OD2 2.77Å; R362-D414 PolarHBondContact NE-OD2 3.21Å; R362-D414 IonicContact NH2-OD1 3.62Å; R362-D414 IonicContact NH2-OD2 3.11Å; R362-D414 PolarHBondContact NH2-OD2 3.41Å; R362-D414 VanDerWaalsContact NH2-OD2 3.11Å
363	K	94.9	Very high	90.7	Very high	44 Å²	44	50.3 Å²	50.3	19%	0.191	26%	0.257	C	S	.	.	H	α-helix	trans	-68.2	-49.2	178.8	-74.8	-176.8	175.1	-165.8	0	111.9	V359 F360 V361 F365 S366 L367 Y472 A473 V474 G476	V359-K363 HydrophobicContact CG1-CD 3.98Å; V359-K363 HydrophobicContact CG1-CG 4.38Å; V359-K363 WeakPolarHBondContact O-CB 3.07Å; V359-K363 WeakPolarHBondContact O-CG 3.32Å; V359-K363 PolarHBondContact O-N 3.48Å; F360-K363 PolarHBondContact O-N 3.04Å; V361-K363 PolarHBondContact O-N 3.03Å; K363-F365 VanDerWaalsContact C-N 3.33Å; K363-F365 PolarHBondContact O-N 2.88Å; K363-S366 PolarHBondContact O-N 3.11Å; K363-L367 WeakPolarHBondContact O-CG 3.23Å; K363-L367 PolarHBondContact O-N 2.86Å; K363-Y472 HydrophobicContact CG-CE1 4.47Å; K363-A473 VanDerWaalsContact CD-O 3.29Å; K363-A473 WeakPolarHBondContact CD-O 3.34Å; K363-A473 WeakPolarHBondContact CE-O 3.15Å; K363-A473 PolarHBondContact NZ-O 3.28Å; K363-V474 PolarHBondContact NZ-O 3.23Å; K363-G476 WeakPolarHBondContact CE-O 3.38Å; K363-G476 PolarHBondContact NZ-O 2.74Å
364	S	94.8	Very high	91.5	Very high	34 Å²	34	46.4 Å²	46.4	24%	0.238	23%	0.233	C	C	.	.	H	α-helix	trans	-59.7	-43.9	-179.1	-62.2	0	0	0	0	112	F360 V361 L367 I368	F360-S364 WeakPolarHBondContact O-CB 3.25Å; F360-S364 PolarHBondContact O-N 2.97Å; F360-S364 PolarHBondContact O-OG 2.92Å; V361-S364 PolarHBondContact O-N 3.14Å; S364-L367 PolarHBondContact O-N 3.4Å; S364-I368 WeakPolarHBondContact O-CG1 3.42Å; S364-I368 PolarHBondContact O-N 3.35Å; S364-I368 VanDerWaalsContact O-N 3.08Å
365	F	94.3	Very high	92.5	Very high	19 Å²	19	43.3 Å²	43.3	8%	0.083	23%	0.231	C	C	.	.	H	α-helix	trans	-68.5	-37.2	179.6	-81.1	-118.2	0	0	0	112.1	S343 V346 A347 L350 V361 K363 G369 V403	S343-F365 VanDerWaalsContact O-CE1 3.25Å; S343-F365 WeakPolarHBondContact O-CE1 3Å; V346-F365 HydrophobicContact CB-CZ 4.21Å; V346-F365 HydrophobicContact CG1-CZ 3.94Å; A347-F365 HydrophobicContact CB-CE1 3.96Å; A347-F365 HydrophobicContact CB-CZ 3.99Å; L350-F365 HydrophobicContact CD1-CE2 3.83Å; L350-F365 HydrophobicContact CD1-CZ 4.08Å; V361-F365 HydrophobicContact CG1-CD2 3.91Å; V361-F365 HydrophobicContact CG1-CE2 3.83Å; V361-F365 HydrophobicContact CG1-CZ 4.49Å; V361-F365 WeakPolarHBondContact O-CB 3.38Å; V361-F365 WeakPolarHBondContact O-CD2 3.43Å; V361-F365 PolarHBondContact O-N 2.97Å; K363-F365 VanDerWaalsContact C-N 3.33Å; K363-F365 PolarHBondContact O-N 2.88Å; F365-G369 PolarHBondContact O-N 2.99Å; F365-V403 HydrophobicContact CB-CG1 4.02Å; F365-V403 HydrophobicContact CD1-CG1 3.55Å; F365-V403 HydrophobicContact CE1-CG1 4.32Å; F365-V403 HydrophobicContact CG-CG1 4.04Å
366	S	95.4	Very high	93.1	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-68.6	-37.6	175.7	-52.9	0	0	0	0	112.1	R362 K363 G369 M370 G407 F408 Y472	R362-S366 WeakPolarHBondContact O-CB 3.3Å; R362-S366 PolarHBondContact O-N 3.05Å; R362-S366 PolarHBondContact O-OG 2.98Å; K363-S366 PolarHBondContact O-N 3.11Å; S366-G369 PolarHBondContact O-N 3.22Å; S366-M370 WeakPolarHBondContact O-CB 3.28Å; S366-M370 VanDerWaalsContact O-CG 3.28Å; S366-M370 WeakPolarHBondContact O-CG 3.32Å; S366-M370 PolarHBondContact O-N 3.36Å; S366-M370 VanDerWaalsContact O-N 3.1Å; S366-G407 VanDerWaalsContact OG-CA 3.22Å; S366-G407 WeakPolarHBondContact OG-CA 3.49Å; S366-F408 PolarHBondContact OG-N 3.47Å; S366-Y472 WeakPolarHBondContact OG-CE1 3.38Å
367	L	96.2	Very high	93.3	Very high	52 Å²	52	34.5 Å²	34.5	27%	0.272	19%	0.19	S	C	.	.	H	α-helix	trans	-61.5	-51	174.7	-78.1	169	0	0	0	111.2	K363 S364 G369 M370 I371 A469 A473	K363-L367 WeakPolarHBondContact O-CG 3.23Å; K363-L367 PolarHBondContact O-N 2.86Å; S364-L367 PolarHBondContact O-N 3.4Å; L367-G369 VanDerWaalsContact C-N 3.34Å; L367-G369 PolarHBondContact O-N 3.33Å; L367-M370 PolarHBondContact O-N 3.02Å; L367-I371 HydrophobicContact CD2-CD1 3.79Å; L367-I371 VanDerWaalsContact O-CB 3.28Å; L367-I371 WeakPolarHBondContact O-CB 3.28Å; L367-I371 WeakPolarHBondContact O-CG1 3.28Å; L367-I371 PolarHBondContact O-N 3.04Å; L367-A469 HydrophobicContact CD2-CB 4.14Å; L367-A473 HydrophobicContact CD1-CB 4.08Å; L367-A473 HydrophobicContact CD2-CB 3.83Å; L367-A473 HydrophobicContact CG-CB 4.06Å
368	I	95.6	Very high	93.6	Very high	91 Å²	91	33 Å²	33	47%	0.467	18%	0.177	S	C	.	.	H	α-helix	trans	-60.6	-46.9	177.6	-66	166.4	0	0	0	110.3	S364 M370 G372 V403	S364-I368 WeakPolarHBondContact O-CG1 3.42Å; S364-I368 PolarHBondContact O-N 3.35Å; S364-I368 VanDerWaalsContact O-N 3.08Å; I368-M370 PolarHBondContact O-N 3.37Å; I368-G372 WeakPolarHBondContact O-CA 3.27Å; I368-G372 PolarHBondContact O-N 3.23Å; I368-V403 HydrophobicContact CB-CG1 4.39Å; I368-V403 HydrophobicContact CG2-CG1 4.25Å; I368-V403 HydrophobicContact CG2-CG2 4.46Å
369	G	94.3	Very high	94	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-76.4	1.2	-175.3	0	0	0	0	0	115.9	F365 S366 L367 P373 L400 G401 S404	F365-G369 PolarHBondContact O-N 2.99Å; S366-G369 PolarHBondContact O-N 3.22Å; L367-G369 VanDerWaalsContact C-N 3.34Å; L367-G369 PolarHBondContact O-N 3.33Å; G369-P373 VanDerWaalsContact O-CG 3.29Å; G369-P373 WeakPolarHBondContact O-CG 3.39Å; G369-L400 VanDerWaalsContact CA-O 3.27Å; G369-L400 WeakPolarHBondContact CA-O 3.21Å; G369-G401 WeakPolarHBondContact O-CA 3.32Å; G369-S404 WeakPolarHBondContact CA-OG 3.49Å; G369-S404 PolarHBondContact O-OG 2.78Å
370	M	95.4	Very high	94	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-124.5	-41.5	174.8	-65.4	179.6	75.3	0	0	112.4	A295 S298 S366 L367 I368 A374 A469	A295-M370 HydrophobicContact CB-SD 4.33Å; S298-M370 VanDerWaalsContact CB-CE 3.44Å; S366-M370 WeakPolarHBondContact O-CB 3.28Å; S366-M370 VanDerWaalsContact O-CG 3.28Å; S366-M370 WeakPolarHBondContact O-CG 3.32Å; S366-M370 PolarHBondContact O-N 3.36Å; S366-M370 VanDerWaalsContact O-N 3.1Å; L367-M370 PolarHBondContact O-N 3.02Å; I368-M370 PolarHBondContact O-N 3.37Å; M370-A374 PolarHBondContact O-N 3.4Å; M370-A469 HydrophobicContact CB-CB 3.7Å; M370-A469 HydrophobicContact SD-CB 4.21Å
371	I	96.6	Very high	93.7	Very high	59 Å²	59	26.1 Å²	26.1	30%	0.303	15%	0.148	S	C	.	.	H	α-helix	trans	-72.5	-40.6	175.9	-61.3	176.5	0	0	0	110.7	L367 A374 V375 A469	L367-I371 HydrophobicContact CD2-CD1 3.79Å; L367-I371 VanDerWaalsContact O-CB 3.28Å; L367-I371 WeakPolarHBondContact O-CB 3.28Å; L367-I371 WeakPolarHBondContact O-CG1 3.28Å; L367-I371 PolarHBondContact O-N 3.04Å; I371-A374 WeakPolarHBondContact O-CB 3.49Å; I371-A374 PolarHBondContact O-N 3.1Å; I371-A374 VanDerWaalsContact O-N 3.17Å; I371-V375 HydrophobicContact CG2-CG2 4.36Å; I371-V375 WeakPolarHBondContact O-CG2 3.29Å; I371-V375 PolarHBondContact O-N 2.75Å; I371-A469 HydrophobicContact CD1-CB 4.31Å; I371-A469 HydrophobicContact CG1-CB 3.83Å
372	G	95.3	Very high	93.6	Very high	15 Å²	15	33.1 Å²	33.1	16%	0.155	18%	0.175	C	C	.	.	H	α-helix	trans	-54.7	-54.4	176.1	0	0	0	0	0	112.6	I368 A374 V375 F376	I368-G372 WeakPolarHBondContact O-CA 3.27Å; I368-G372 PolarHBondContact O-N 3.23Å; G372-A374 VanDerWaalsContact C-N 3.3Å; G372-A374 PolarHBondContact O-N 3.46Å; G372-V375 PolarHBondContact O-N 2.88Å; G372-F376 WeakPolarHBondContact O-CD2 3.44Å; G372-F376 PolarHBondContact O-N 2.93Å
373	P	94.8	Very high	93.3	Very high	5 Å²	5	33.5 Å²	33.5	3%	0.032	18%	0.178	C	C	.	.	H	α-helix	trans	-53.4	-43.9	173	-27.3	32.5	0	0	0	113.9	G369 V375 F376 L377 S397 L400	G369-P373 VanDerWaalsContact O-CG 3.29Å; G369-P373 WeakPolarHBondContact O-CG 3.39Å; P373-V375 PolarHBondContact O-N 3.47Å; P373-F376 PolarHBondContact O-N 3.24Å; P373-L377 WeakPolarHBondContact O-CB 3.34Å; P373-L377 PolarHBondContact O-N 3.05Å; P373-S397 VanDerWaalsContact CA-OG 3.24Å; P373-S397 WeakPolarHBondContact CA-OG 3.09Å; P373-S397 WeakPolarHBondContact CG-O 3.45Å; P373-S397 PolarHBondContact O-OG 3.17Å; P373-L400 HydrophobicContact CG-CB 4.31Å
374	A	94.8	Very high	92.6	Very high	3 Å²	3	33.1 Å²	33.1	3%	0.025	19%	0.187	C	C	.	.	H	α-helix	trans	-60.1	-45	-179.6	0	0	0	0	0	112.5	M370 I371 G372 L377 V378 A462 N465 V466	M370-A374 PolarHBondContact O-N 3.4Å; I371-A374 WeakPolarHBondContact O-CB 3.49Å; I371-A374 PolarHBondContact O-N 3.1Å; I371-A374 VanDerWaalsContact O-N 3.17Å; G372-A374 VanDerWaalsContact C-N 3.3Å; G372-A374 PolarHBondContact O-N 3.46Å; A374-L377 PolarHBondContact O-N 3.48Å; A374-V378 WeakPolarHBondContact O-CG2 3.27Å; A374-V378 PolarHBondContact O-N 3.48Å; A374-V378 VanDerWaalsContact O-N 3.13Å; A374-A462 HydrophobicContact CB-CB 3.88Å; A374-N465 HydrophobicContact CB-CB 4.01Å; A374-V466 HydrophobicContact CB-CG2 4Å
375	V	96.1	Very high	91.6	Very high	88 Å²	88	34.5 Å²	34.5	53%	0.533	20%	0.196	S	C	.	.	H	α-helix	trans	-61.9	-49.4	178.7	173	0	0	0	0	111.1	I371 G372 P373 L377 V378 A379	I371-V375 HydrophobicContact CG2-CG2 4.36Å; I371-V375 WeakPolarHBondContact O-CG2 3.29Å; I371-V375 PolarHBondContact O-N 2.75Å; G372-V375 PolarHBondContact O-N 2.88Å; P373-V375 PolarHBondContact O-N 3.47Å; V375-L377 VanDerWaalsContact C-N 3.35Å; V375-L377 PolarHBondContact O-N 3.38Å; V375-V378 PolarHBondContact O-N 3.41Å; V375-A379 WeakPolarHBondContact O-CB 3.12Å; V375-A379 PolarHBondContact O-N 3.38Å
376	F	95.1	Very high	91	Very high	57 Å²	57	40.5 Å²	40.5	25%	0.25	22%	0.222	C	C	.	.	H	α-helix	trans	-72.7	-27.4	-178	-80.2	-80	0	0	0	113.3	G372 P373 A379 A380 F393 I396 L400	G372-F376 WeakPolarHBondContact O-CD2 3.44Å; G372-F376 PolarHBondContact O-N 2.93Å; P373-F376 PolarHBondContact O-N 3.24Å; F376-A379 PolarHBondContact O-N 3.4Å; F376-A380 WeakPolarHBondContact O-CB 3.33Å; F376-A380 PolarHBondContact O-N 3.08Å; F376-F393 HydrophobicContact CD1-CB 4.4Å; F376-F393 AromaticContact CD1-CD1 3.91Å; F376-F393 HydrophobicContact CD1-CD1 3.91Å; F376-F393 HydrophobicContact CD1-CE1 4.49Å; F376-F393 HydrophobicContact CD1-CG 4.28Å; F376-F393 HydrophobicContact CE1-CD1 4.16Å; F376-F393 HydrophobicContact CE1-CE1 4.39Å; F376-I396 HydrophobicContact CD1-CB 4.12Å; F376-I396 HydrophobicContact CD1-CG2 3.85Å; F376-I396 HydrophobicContact CD2-CG2 3.67Å; F376-I396 HydrophobicContact CE1-CB 4.29Å; F376-I396 HydrophobicContact CE1-CD1 4.09Å; F376-I396 HydrophobicContact CE1-CG2 3.76Å; F376-I396 HydrophobicContact CE2-CG2 3.58Å; F376-I396 HydrophobicContact CG-CB 4.28Å; F376-I396 HydrophobicContact CG-CG2 3.81Å; F376-I396 HydrophobicContact CZ-CG2 3.62Å; F376-L400 HydrophobicContact CD2-CD1 3.7Å; F376-L400 HydrophobicContact CE2-CD1 3.73Å
377	L	91.3	Very high	90.3	Very high	3 Å²	3	41.8 Å²	41.8	2%	0.016	23%	0.227	C	C	.	.	H	α-helix	trans	-67.9	-43.7	174.4	-165.8	71.4	0	0	0	111.1	T302 L306 P373 A374 V375 A380 G381 L394 F458 A461	T302-L377 HydrophobicContact CG2-CD2 4.22Å; L306-L377 HydrophobicContact CD2-CD1 3.99Å; P373-L377 WeakPolarHBondContact O-CB 3.34Å; P373-L377 PolarHBondContact O-N 3.05Å; A374-L377 PolarHBondContact O-N 3.48Å; V375-L377 VanDerWaalsContact C-N 3.35Å; V375-L377 PolarHBondContact O-N 3.38Å; L377-A380 WeakPolarHBondContact O-CB 3.48Å; L377-A380 PolarHBondContact O-N 3.43Å; L377-G381 PolarHBondContact O-N 2.96Å; L377-L394 HydrophobicContact CD1-CD2 3.84Å; L377-F458 HydrophobicContact CD1-CD1 3.61Å; L377-F458 HydrophobicContact CD1-CE1 3.81Å; L377-F458 HydrophobicContact CD1-CG 4.28Å; L377-F458 HydrophobicContact CD2-CB 4.32Å; L377-F458 HydrophobicContact CD2-CD1 4.01Å; L377-F458 HydrophobicContact CD2-CG 4.5Å; L377-F458 HydrophobicContact CG-CB 3.95Å; L377-F458 HydrophobicContact CG-CD1 3.57Å; L377-F458 HydrophobicContact CG-CE1 4.29Å; L377-F458 HydrophobicContact CG-CG 3.87Å; L377-F458 WeakPolarHBondContact O-CD2 3.21Å; L377-A461 HydrophobicContact CD2-CB 3.42Å; L377-A461 VanDerWaalsContact CD2-CB 3.42Å
378	V	93.2	Very high	89.6	Confident	40 Å²	40	43.6 Å²	43.6	24%	0.242	24%	0.244	C	C	.	.	H	α-helix	trans	-62.2	-46.5	172.3	171.9	0	0	0	0	110.5	A374 V375 A380 G381 Y382 Y459 A462	A374-V378 WeakPolarHBondContact O-CG2 3.27Å; A374-V378 PolarHBondContact O-N 3.48Å; A374-V378 VanDerWaalsContact O-N 3.13Å; V375-V378 PolarHBondContact O-N 3.41Å; V378-A380 PolarHBondContact O-N 2.95Å; V378-G381 PolarHBondContact O-N 3.31Å; V378-Y382 HydrophobicContact CG1-CD2 4.24Å; V378-Y382 HydrophobicContact CG1-CE2 3.99Å; V378-Y382 WeakPolarHBondContact O-CD2 3.27Å; V378-Y459 HydrophobicContact CG1-CD1 4.33Å; V378-Y459 HydrophobicContact CG1-CE1 3.85Å; V378-Y459 HydrophobicContact CG2-CD1 3.99Å; V378-Y459 HydrophobicContact CG2-CE1 4.35Å; V378-A462 HydrophobicContact CG2-CB 3.55Å
379	A	92.6	Very high	89.2	Confident	30 Å²	30	42.3 Å²	42.3	25%	0.248	24%	0.237	C	C	.	.	H	α-helix	trans	-57.9	-36.5	178	0	0	0	0	0	112.6	V375 F376 G381 Y382 F393	V375-A379 WeakPolarHBondContact O-CB 3.12Å; V375-A379 PolarHBondContact O-N 3.38Å; F376-A379 PolarHBondContact O-N 3.4Å; A379-G381 VanDerWaalsContact C-N 3.29Å; A379-G381 PolarHBondContact O-N 3Å; A379-Y382 PolarHBondContact O-N 2.9Å; A379-Y382 VanDerWaalsContact O-N 3.13Å; A379-F393 HydrophobicContact CB-CD2 3.82Å; A379-F393 HydrophobicContact CB-CE2 3.95Å; A379-F393 HydrophobicContact CB-CG 4.47Å
380	A	88.9	Confident	88.9	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-59.7	-38	176.1	0	0	0	0	0	112.4	F376 L377 V378 Y382 T383 F393 L394 F458	F376-A380 WeakPolarHBondContact O-CB 3.33Å; F376-A380 PolarHBondContact O-N 3.08Å; L377-A380 WeakPolarHBondContact O-CB 3.48Å; L377-A380 PolarHBondContact O-N 3.43Å; V378-A380 PolarHBondContact O-N 2.95Å; A380-Y382 PolarHBondContact O-N 3.35Å; A380-T383 WeakPolarHBondContact O-CG2 3.28Å; A380-T383 PolarHBondContact O-N 3.49Å; A380-T383 PolarHBondContact O-OG1 2.83Å; A380-F393 HydrophobicContact CB-CB 3.98Å; A380-L394 HydrophobicContact CB-CD2 3.91Å; A380-L394 HydrophobicContact CB-CG 4.05Å; A380-F458 HydrophobicContact CB-CE2 4.42Å
381	G	86	Confident	88.5	Confident	2 Å²	2	42.7 Å²	42.7	2%	0.021	24%	0.24	C	C	.	.	H	α-helix	trans	-63.9	-20.6	176.3	0	0	0	0	0	114.7	L377 V378 A379 Q455	L377-G381 PolarHBondContact O-N 2.96Å; V378-G381 PolarHBondContact O-N 3.31Å; A379-G381 VanDerWaalsContact C-N 3.29Å; A379-G381 PolarHBondContact O-N 3Å; G381-Q455 VanDerWaalsContact O-CG 3.32Å; G381-Q455 WeakPolarHBondContact O-CG 3.36Å; G381-Q455 PolarHBondContact O-NE2 3.33Å
382	Y	88.4	Confident	88.2	Confident	149 Å²	149	43.1 Å²	43.1	58%	0.584	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	-102.5	11.6	-178.5	-74.4	-82.9	0	0	0	114.1	V378 A379 A380 G384 Y459	V378-Y382 HydrophobicContact CG1-CD2 4.24Å; V378-Y382 HydrophobicContact CG1-CE2 3.99Å; V378-Y382 WeakPolarHBondContact O-CD2 3.27Å; A379-Y382 PolarHBondContact O-N 2.9Å; A379-Y382 VanDerWaalsContact O-N 3.13Å; A380-Y382 PolarHBondContact O-N 3.35Å; Y382-G384 VanDerWaalsContact C-N 3.25Å; Y382-G384 PolarHBondContact O-N 3.2Å; Y382-Y459 HydrophobicContact CE2-CE1 4.12Å; Y382-Y459 WeakPolarHBondContact CE2-OH 3.5Å; Y382-Y459 PolarHBondContact OH-OH 2.9Å
383	T	85.5	Confident	88.1	Confident	13 Å²	13	44.6 Å²	44.6	8%	0.08	25%	0.247	C	C	.	.			trans	-75.5	-12.7	-178	54.3	0	0	0	0	114	A380 K386 L389 A390 F393	A380-T383 WeakPolarHBondContact O-CG2 3.28Å; A380-T383 PolarHBondContact O-N 3.49Å; A380-T383 PolarHBondContact O-OG1 2.83Å; T383-K386 PolarHBondContact O-N 3.13Å; T383-L389 HydrophobicContact CG2-CB 4.22Å; T383-L389 HydrophobicContact CG2-CD2 3.97Å; T383-L389 HydrophobicContact CG2-CG 3.85Å; T383-A390 HydrophobicContact CG2-CB 4.42Å; T383-A390 WeakPolarHBondContact OG1-CB 3.29Å; T383-F393 HydrophobicContact CG2-CD2 3.52Å; T383-F393 HydrophobicContact CG2-CE2 3.75Å
384	G	79.3	Confident	87.9	Confident	36 Å²	36	44.4 Å²	44.4	37%	0.371	25%	0.246	S	C	.	.	T	Hydrogen-bonded Turn	trans	58.7	-134.9	-177.1	0	0	0	0	0	111.2	Y382 K386	Y382-G384 VanDerWaalsContact C-N 3.25Å; Y382-G384 PolarHBondContact O-N 3.2Å; G384-K386 VanDerWaalsContact C-N 3.25Å; G384-K386 PolarHBondContact O-N 2.85Å
385	C	75.1	Confident	87.8	Confident	63 Å²	63	45.7 Å²	45.7	43%	0.426	25%	0.254	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.2	8.2	-179.4	-51.9	0	0	0	0	114.6	C80 Y387	C80-C385 VanDerWaalsContact CA-SG 3.53Å; C80-C385 HydrophobicContact CB-CB 3.65Å; C80-C385 WeakPolarHBondContact CB-SG 3.45Å; C80-C385 WeakPolarHBondContact SG-CA 3.13Å; C80-C385 WeakPolarHBondContact SG-CB 3.47Å; C80-C385 CovalentContact SG-SG 2.03Å; C80-C385 PolarHBondContact SG-SG 3.39Å; C385-Y387 PolarHBondContact O-N 3.4Å; C385-Y387 VanDerWaalsContact O-N 3.12Å
386	K	81.7	Confident	87.7	Confident	145 Å²	145	44.3 Å²	44.3	63%	0.63	24%	0.243	S	C	*	.			trans	-86.9	77.5	180	-65.7	-179.4	-178	175.7	0	110.4	T383 G384 S388 L389 A390	T383-K386 PolarHBondContact O-N 3.13Å; G384-K386 VanDerWaalsContact C-N 3.25Å; G384-K386 PolarHBondContact O-N 2.85Å; K386-S388 VanDerWaalsContact C-N 3.33Å; K386-S388 PolarHBondContact O-N 2.93Å; K386-L389 HydrophobicContact CB-CB 3.97Å; K386-L389 HydrophobicContact CB-CD2 4.5Å; K386-L389 HydrophobicContact CD-CD2 4.39Å; K386-L389 WeakPolarHBondContact O-CB 3.46Å; K386-L389 PolarHBondContact O-N 3.05Å; K386-A390 PolarHBondContact O-N 2.9Å
387	Y	79.2	Confident	87.7	Confident	26 Å²	26	41.6 Å²	41.6	10%	0.102	23%	0.231	C	C	.	.	H	α-helix	trans	-56.2	-40.7	-173.3	-49.4	-51.2	0	0	0	114	C80 T81 L318 C385 L389 A390 V391	C80-Y387 HydrophobicContact CB-CE1 4.31Å; C80-Y387 WeakPolarHBondContact CB-OH 3.38Å; T81-Y387 PolarHBondContact O-OH 3.39Å; T81-Y387 VanDerWaalsContact O-OH 3.05Å; L318-Y387 HydrophobicContact CB-CD1 4.06Å; L318-Y387 HydrophobicContact CB-CG 4.35Å; L318-Y387 HydrophobicContact CD2-CD1 3.41Å; L318-Y387 VanDerWaalsContact CD2-CD1 3.41Å; L318-Y387 HydrophobicContact CD2-CE1 4.11Å; L318-Y387 HydrophobicContact CD2-CG 4.24Å; L318-Y387 HydrophobicContact CG-CD1 4.3Å; C385-Y387 PolarHBondContact O-N 3.4Å; C385-Y387 VanDerWaalsContact O-N 3.12Å; Y387-L389 VanDerWaalsContact C-N 3.27Å; Y387-L389 PolarHBondContact O-N 3.23Å; Y387-A390 WeakPolarHBondContact O-CB 3.33Å; Y387-A390 PolarHBondContact O-N 3.32Å; Y387-A390 VanDerWaalsContact O-N 3.17Å; Y387-V391 WeakPolarHBondContact O-CG2 3.48Å; Y387-V391 PolarHBondContact O-N 3.39Å; Y387-V391 VanDerWaalsContact O-N 3.08Å
388	S	82.8	Confident	87.7	Confident	91 Å²	91	42.2 Å²	42.2	64%	0.636	24%	0.235	S	C	*	.	H	α-helix	trans	-62.1	-33.6	177.1	55.5	0	0	0	0	113.3	K386 T392	K386-S388 VanDerWaalsContact C-N 3.33Å; K386-S388 PolarHBondContact O-N 2.93Å; S388-T392 WeakPolarHBondContact O-CB 3.4Å; S388-T392 PolarHBondContact O-N 3.15Å; S388-T392 VanDerWaalsContact O-N 3.07Å; S388-T392 PolarHBondContact O-OG1 3.38Å
389	L	87.8	Confident	87.8	Confident	63 Å²	63	41 Å²	41	33%	0.33	23%	0.23	S	C	.	.	H	α-helix	trans	-71.2	-39.7	176.3	-171	65.3	0	0	0	110.9	T383 K386 Y387 T392 F393	T383-L389 HydrophobicContact CG2-CB 4.22Å; T383-L389 HydrophobicContact CG2-CD2 3.97Å; T383-L389 HydrophobicContact CG2-CG 3.85Å; K386-L389 HydrophobicContact CB-CB 3.97Å; K386-L389 HydrophobicContact CB-CD2 4.5Å; K386-L389 HydrophobicContact CD-CD2 4.39Å; K386-L389 WeakPolarHBondContact O-CB 3.46Å; K386-L389 PolarHBondContact O-N 3.05Å; Y387-L389 VanDerWaalsContact C-N 3.27Å; Y387-L389 PolarHBondContact O-N 3.23Å; L389-T392 WeakPolarHBondContact O-CB 3.35Å; L389-T392 PolarHBondContact O-N 3.21Å; L389-F393 HydrophobicContact CD1-CD1 4.44Å; L389-F393 HydrophobicContact CD1-CE1 3.85Å; L389-F393 HydrophobicContact CD1-CE2 4.16Å; L389-F393 HydrophobicContact CD1-CZ 3.69Å; L389-F393 HydrophobicContact CD2-CE2 4.18Å; L389-F393 HydrophobicContact CD2-CZ 4.31Å; L389-F393 HydrophobicContact CG-CD2 4.32Å; L389-F393 HydrophobicContact CG-CE1 4.42Å; L389-F393 HydrophobicContact CG-CE2 3.89Å; L389-F393 HydrophobicContact CG-CZ 3.95Å; L389-F393 PolarHBondContact O-N 3.5Å
390	A	86.4	Confident	87.9	Confident	0 Å²	0	41.7 Å²	41.7	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-58.4	-50.7	174.6	0	0	0	0	0	111.3	L318 T383 K386 Y387 T392 F393 L394	L318-A390 HydrophobicContact CD2-CB 4.43Å; T383-A390 HydrophobicContact CG2-CB 4.42Å; T383-A390 WeakPolarHBondContact OG1-CB 3.29Å; K386-A390 PolarHBondContact O-N 2.9Å; Y387-A390 WeakPolarHBondContact O-CB 3.33Å; Y387-A390 PolarHBondContact O-N 3.32Å; Y387-A390 VanDerWaalsContact O-N 3.17Å; A390-T392 VanDerWaalsContact C-N 3.29Å; A390-T392 PolarHBondContact O-N 3.41Å; A390-F393 PolarHBondContact O-N 3.44Å; A390-L394 VanDerWaalsContact O-CG 3.27Å; A390-L394 WeakPolarHBondContact O-CG 3.36Å; A390-L394 PolarHBondContact O-N 3.18Å
391	V	87.3	Confident	88	Confident	8 Å²	8	41.8 Å²	41.8	5%	0.048	23%	0.23	C	C	.	.	H	α-helix	trans	-60	-40.5	177.1	-177.5	0	0	0	0	111.3	M314 L318 F320 L328 L331 Y387 L394 T395	M314-V391 HydrophobicContact CE-CB 4.41Å; M314-V391 HydrophobicContact CE-CG1 4.28Å; M314-V391 HydrophobicContact CE-CG2 3.78Å; M314-V391 HydrophobicContact SD-CG2 3.81Å; L318-V391 HydrophobicContact CD1-CG2 4.21Å; F320-V391 HydrophobicContact CE2-CG2 4.11Å; L328-V391 HydrophobicContact CD2-CG1 4.39Å; L331-V391 HydrophobicContact CD1-CG1 4.27Å; Y387-V391 WeakPolarHBondContact O-CG2 3.48Å; Y387-V391 PolarHBondContact O-N 3.39Å; Y387-V391 VanDerWaalsContact O-N 3.08Å; V391-L394 PolarHBondContact O-N 2.99Å; V391-T395 VanDerWaalsContact O-CB 3.32Å; V391-T395 WeakPolarHBondContact O-CB 3.45Å; V391-T395 PolarHBondContact O-N 3.11Å; V391-T395 PolarHBondContact O-OG1 2.98Å
392	T	90.7	Very high	88.3	Confident	68 Å²	68	41.8 Å²	41.8	42%	0.417	23%	0.23	S	C	.	.	H	α-helix	trans	-62.2	-47	178.4	-58.8	0	0	0	0	111.5	S388 L389 A390 T395 I396	S388-T392 WeakPolarHBondContact O-CB 3.4Å; S388-T392 PolarHBondContact O-N 3.15Å; S388-T392 VanDerWaalsContact O-N 3.07Å; S388-T392 PolarHBondContact O-OG1 3.38Å; L389-T392 WeakPolarHBondContact O-CB 3.35Å; L389-T392 PolarHBondContact O-N 3.21Å; A390-T392 VanDerWaalsContact C-N 3.29Å; A390-T392 PolarHBondContact O-N 3.41Å; T392-T395 WeakPolarHBondContact O-CB 3.48Å; T392-T395 PolarHBondContact O-N 3.32Å; T392-I396 HydrophobicContact CG2-CD1 3.92Å; T392-I396 WeakPolarHBondContact O-CG1 3.29Å; T392-I396 PolarHBondContact O-N 3.38Å
393	F	93.3	Very high	88.5	Confident	46 Å²	46	35.1 Å²	35.1	20%	0.202	21%	0.205	C	C	.	.	H	α-helix	trans	-67.2	-39.7	178.7	-70.7	-13.7	0	0	0	112.9	F376 A379 A380 T383 L389 A390 T395 I396 S397	F376-F393 HydrophobicContact CD1-CB 4.4Å; F376-F393 AromaticContact CD1-CD1 3.91Å; F376-F393 HydrophobicContact CD1-CD1 3.91Å; F376-F393 HydrophobicContact CD1-CE1 4.49Å; F376-F393 HydrophobicContact CD1-CG 4.28Å; F376-F393 HydrophobicContact CE1-CD1 4.16Å; F376-F393 HydrophobicContact CE1-CE1 4.39Å; A379-F393 HydrophobicContact CB-CD2 3.82Å; A379-F393 HydrophobicContact CB-CE2 3.95Å; A379-F393 HydrophobicContact CB-CG 4.47Å; A380-F393 HydrophobicContact CB-CB 3.98Å; T383-F393 HydrophobicContact CG2-CD2 3.52Å; T383-F393 HydrophobicContact CG2-CE2 3.75Å; L389-F393 HydrophobicContact CD1-CD1 4.44Å; L389-F393 HydrophobicContact CD1-CE1 3.85Å; L389-F393 HydrophobicContact CD1-CE2 4.16Å; L389-F393 HydrophobicContact CD1-CZ 3.69Å; L389-F393 HydrophobicContact CD2-CE2 4.18Å; L389-F393 HydrophobicContact CD2-CZ 4.31Å; L389-F393 HydrophobicContact CG-CD2 4.32Å; L389-F393 HydrophobicContact CG-CE1 4.42Å; L389-F393 HydrophobicContact CG-CE2 3.89Å; L389-F393 HydrophobicContact CG-CZ 3.95Å; L389-F393 PolarHBondContact O-N 3.5Å; A390-F393 PolarHBondContact O-N 3.44Å; F393-T395 VanDerWaalsContact C-N 3.28Å; F393-T395 PolarHBondContact O-N 3.46Å; F393-I396 PolarHBondContact O-N 3.17Å; F393-S397 VanDerWaalsContact O-CB 3.28Å; F393-S397 WeakPolarHBondContact O-CB 3.18Å; F393-S397 PolarHBondContact O-N 3.2Å
394	L	90.9	Very high	88.7	Confident	1 Å²	1	34.5 Å²	34.5	1%	0.005	20%	0.201	C	C	.	.	H	α-helix	trans	-62.7	-37.5	173.5	-67.2	171.2	0	0	0	111.7	L306 L310 Y313 M314 L377 A380 A390 V391 S398 F458	L306-L394 HydrophobicContact CD2-CD2 3.91Å; L310-L394 HydrophobicContact CD1-CD1 3.69Å; Y313-L394 HydrophobicContact CD1-CD1 4.26Å; Y313-L394 HydrophobicContact CE1-CD1 3.96Å; M314-L394 HydrophobicContact CE-CD1 4.1Å; L377-L394 HydrophobicContact CD1-CD2 3.84Å; A380-L394 HydrophobicContact CB-CD2 3.91Å; A380-L394 HydrophobicContact CB-CG 4.05Å; A390-L394 VanDerWaalsContact O-CG 3.27Å; A390-L394 WeakPolarHBondContact O-CG 3.36Å; A390-L394 PolarHBondContact O-N 3.18Å; V391-L394 PolarHBondContact O-N 2.99Å; L394-S398 PolarHBondContact O-N 3.21Å; L394-S398 PolarHBondContact O-OG 2.92Å; L394-F458 HydrophobicContact CD2-CZ 4.36Å
395	T	92.2	Very high	89.1	Confident	30 Å²	30	34 Å²	34	18%	0.184	19%	0.193	C	C	.	.	H	α-helix	trans	-66.3	-48	175.9	-59.4	0	0	0	0	111.5	L331 V391 T392 F393 S397 S398 A399	L331-T395 HydrophobicContact CB-CG2 4.31Å; V391-T395 VanDerWaalsContact O-CB 3.32Å; V391-T395 WeakPolarHBondContact O-CB 3.45Å; V391-T395 PolarHBondContact O-N 3.11Å; V391-T395 PolarHBondContact O-OG1 2.98Å; T392-T395 WeakPolarHBondContact O-CB 3.48Å; T392-T395 PolarHBondContact O-N 3.32Å; F393-T395 VanDerWaalsContact C-N 3.28Å; F393-T395 PolarHBondContact O-N 3.46Å; T395-S397 VanDerWaalsContact C-N 3.33Å; T395-S397 PolarHBondContact O-N 2.97Å; T395-S398 PolarHBondContact O-N 3.33Å; T395-A399 VanDerWaalsContact O-CB 3.27Å; T395-A399 WeakPolarHBondContact O-CB 3.44Å; T395-A399 PolarHBondContact O-N 3.33Å
396	I	94.7	Very high	89.7	Confident	59 Å²	59	31 Å²	31	30%	0.303	17%	0.173	S	C	.	.	H	α-helix	trans	-63.3	-41.2	177.3	-65.7	167.1	0	0	0	110.7	F376 T392 F393 S398 A399 L400	F376-I396 HydrophobicContact CD1-CB 4.12Å; F376-I396 HydrophobicContact CD1-CG2 3.85Å; F376-I396 HydrophobicContact CD2-CG2 3.67Å; F376-I396 HydrophobicContact CE1-CB 4.29Å; F376-I396 HydrophobicContact CE1-CD1 4.09Å; F376-I396 HydrophobicContact CE1-CG2 3.76Å; F376-I396 HydrophobicContact CE2-CG2 3.58Å; F376-I396 HydrophobicContact CG-CB 4.28Å; F376-I396 HydrophobicContact CG-CG2 3.81Å; F376-I396 HydrophobicContact CZ-CG2 3.62Å; T392-I396 HydrophobicContact CG2-CD1 3.92Å; T392-I396 WeakPolarHBondContact O-CG1 3.29Å; T392-I396 PolarHBondContact O-N 3.38Å; F393-I396 PolarHBondContact O-N 3.17Å; I396-S398 PolarHBondContact O-N 3.03Å; I396-A399 PolarHBondContact O-N 3.27Å; I396-L400 HydrophobicContact CG2-CD1 4.06Å; I396-L400 HydrophobicContact CG2-CG 4.33Å; I396-L400 WeakPolarHBondContact O-CG 3.5Å; I396-L400 PolarHBondContact O-N 3.04Å
397	S	94.2	Very high	90.1	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-55.7	-52.6	176.2	-179.8	0	0	0	0	111.1	P373 F393 T395 A399 L400 G401	P373-S397 VanDerWaalsContact CA-OG 3.24Å; P373-S397 WeakPolarHBondContact CA-OG 3.09Å; P373-S397 WeakPolarHBondContact CG-O 3.45Å; P373-S397 PolarHBondContact O-OG 3.17Å; F393-S397 VanDerWaalsContact O-CB 3.28Å; F393-S397 WeakPolarHBondContact O-CB 3.18Å; F393-S397 PolarHBondContact O-N 3.2Å; T395-S397 VanDerWaalsContact C-N 3.33Å; T395-S397 PolarHBondContact O-N 2.97Å; S397-A399 PolarHBondContact O-N 3.37Å; S397-L400 PolarHBondContact O-N 3.22Å; S397-G401 PolarHBondContact O-N 2.88Å
398	S	92.2	Very high	90.6	Very high	16 Å²	16	22.9 Å²	22.9	11%	0.112	14%	0.138	C	C	.	.	H	α-helix	trans	-68	-35.8	179.5	-59.6	0	0	0	0	112.9	L306 P332 C336 L394 T395 I396 G401 G402	L306-S398 WeakPolarHBondContact CD1-OG 2.99Å; P332-S398 WeakPolarHBondContact CB-OG 3.36Å; P332-S398 VanDerWaalsContact O-CB 3.28Å; P332-S398 WeakPolarHBondContact O-CB 3.44Å; C336-S398 WeakPolarHBondContact CB-O 3.49Å; C336-S398 PolarHBondContact SG-O 2.95Å; C336-S398 VanDerWaalsContact SG-O 3.38Å; L394-S398 PolarHBondContact O-N 3.21Å; L394-S398 PolarHBondContact O-OG 2.92Å; T395-S398 PolarHBondContact O-N 3.33Å; I396-S398 PolarHBondContact O-N 3.03Å; S398-G401 WeakPolarHBondContact O-CA 3.45Å; S398-G401 PolarHBondContact O-N 3.25Å; S398-G401 VanDerWaalsContact O-N 3.15Å; S398-G402 PolarHBondContact O-N 3.4Å
399	A	94.3	Very high	90.8	Very high	15 Å²	15	20.1 Å²	20.1	12%	0.124	12%	0.116	C	C	.	.	H	α-helix	trans	-61	-49.3	175.5	0	0	0	0	0	111.7	M339 T395 I396 S397 G401 G402	M339-A399 WeakPolarHBondContact CB-O 3.17Å; M339-A399 HydrophobicContact CG-CB 4Å; M339-A399 WeakPolarHBondContact CG-O 3.35Å; T395-A399 VanDerWaalsContact O-CB 3.27Å; T395-A399 WeakPolarHBondContact O-CB 3.44Å; T395-A399 PolarHBondContact O-N 3.33Å; I396-A399 PolarHBondContact O-N 3.27Å; S397-A399 PolarHBondContact O-N 3.37Å; A399-G401 PolarHBondContact O-N 3.48Å; A399-G402 PolarHBondContact O-N 2.95Å
400	L	95	Very high	90.8	Very high	44 Å²	44	17.4 Å²	17.4	23%	0.23	10%	0.102	C	C	.	.	H	α-helix	trans	-60.7	-34.9	173.9	-68.1	175.7	0	0	0	111.4	G369 P373 F376 I396 S397 G402 V403	G369-L400 VanDerWaalsContact CA-O 3.27Å; G369-L400 WeakPolarHBondContact CA-O 3.21Å; P373-L400 HydrophobicContact CG-CB 4.31Å; F376-L400 HydrophobicContact CD2-CD1 3.7Å; F376-L400 HydrophobicContact CE2-CD1 3.73Å; I396-L400 HydrophobicContact CG2-CD1 4.06Å; I396-L400 HydrophobicContact CG2-CG 4.33Å; I396-L400 WeakPolarHBondContact O-CG 3.5Å; I396-L400 PolarHBondContact O-N 3.04Å; S397-L400 PolarHBondContact O-N 3.22Å; L400-G402 PolarHBondContact O-N 3.03Å; L400-V403 VanDerWaalsContact O-CB 3.27Å; L400-V403 WeakPolarHBondContact O-CB 3.45Å; L400-V403 WeakPolarHBondContact O-CG2 3.22Å; L400-V403 PolarHBondContact O-N 3.47Å
401	G	92.1	Very high	90.9	Very high	3 Å²	3	17.4 Å²	17.4	3%	0.031	10%	0.102	C	C	.	.	H	α-helix	trans	-54.6	-33.4	172.6	0	0	0	0	0	113.5	Y299 G369 S397 S398 A399 V403 S404	Y299-G401 VanDerWaalsContact CE2-O 3.32Å; Y299-G401 WeakPolarHBondContact CE2-O 3.15Å; G369-G401 WeakPolarHBondContact O-CA 3.32Å; S397-G401 PolarHBondContact O-N 2.88Å; S398-G401 WeakPolarHBondContact O-CA 3.45Å; S398-G401 PolarHBondContact O-N 3.25Å; S398-G401 VanDerWaalsContact O-N 3.15Å; A399-G401 PolarHBondContact O-N 3.48Å; G401-V403 PolarHBondContact O-N 3.47Å; G401-S404 VanDerWaalsContact O-CB 3.28Å; G401-S404 WeakPolarHBondContact O-CB 3.4Å; G401-S404 PolarHBondContact O-N 3.48Å; G401-S404 VanDerWaalsContact O-N 3.11Å
402	G	90.4	Very high	91	Very high	1 Å²	1	17 Å²	17	1%	0.01	10%	0.1	C	C	.	.	H	α-helix	trans	-59.2	-28	176.3	0	0	0	0	0	113.7	C336 A340 S398 A399 L400 S404 A405	C336-G402 VanDerWaalsContact SG-CA 3.58Å; A340-G402 WeakPolarHBondContact CA-O 3.12Å; S398-G402 PolarHBondContact O-N 3.4Å; A399-G402 PolarHBondContact O-N 2.95Å; L400-G402 PolarHBondContact O-N 3.03Å; G402-S404 PolarHBondContact O-N 2.96Å; G402-A405 WeakPolarHBondContact O-CB 3.37Å; G402-A405 PolarHBondContact O-N 3.39Å
403	V	92.9	Very high	90.6	Very high	10 Å²	10	13.9 Å²	13.9	6%	0.061	8%	0.08	C	C	.	.	G	3₁₀ helix	trans	-60.9	-27.8	177.6	-177.2	0	0	0	0	111.9	M339 F365 I368 L400 G401 A405 S406	M339-V403 HydrophobicContact CE-CG2 4.17Å; F365-V403 HydrophobicContact CB-CG1 4.02Å; F365-V403 HydrophobicContact CD1-CG1 3.55Å; F365-V403 HydrophobicContact CE1-CG1 4.32Å; F365-V403 HydrophobicContact CG-CG1 4.04Å; I368-V403 HydrophobicContact CB-CG1 4.39Å; I368-V403 HydrophobicContact CG2-CG1 4.25Å; I368-V403 HydrophobicContact CG2-CG2 4.46Å; L400-V403 VanDerWaalsContact O-CB 3.27Å; L400-V403 WeakPolarHBondContact O-CB 3.45Å; L400-V403 WeakPolarHBondContact O-CG2 3.22Å; L400-V403 PolarHBondContact O-N 3.47Å; G401-V403 PolarHBondContact O-N 3.47Å; V403-A405 PolarHBondContact O-N 3.2Å; V403-S406 PolarHBondContact O-N 2.99Å; V403-S406 VanDerWaalsContact O-N 3.15Å
404	S	90.9	Very high	90.2	Very high	0 Å²	0	13 Å²	13	0%	0	8%	0.078	C	C	.	.	G	3₁₀ helix	trans	-63.8	-19.2	176.1	-66	0	0	0	0	113.6	G369 G401 G402 S406 G407	G369-S404 WeakPolarHBondContact CA-OG 3.49Å; G369-S404 PolarHBondContact O-OG 2.78Å; G401-S404 VanDerWaalsContact O-CB 3.28Å; G401-S404 WeakPolarHBondContact O-CB 3.4Å; G401-S404 PolarHBondContact O-N 3.48Å; G401-S404 VanDerWaalsContact O-N 3.11Å; G402-S404 PolarHBondContact O-N 2.96Å; S404-S406 PolarHBondContact O-N 2.84Å; S404-G407 WeakPolarHBondContact O-CA 3.4Å; S404-G407 PolarHBondContact O-N 3.31Å
405	A	86.4	Confident	90.1	Very high	24 Å²	24	13 Å²	13	20%	0.198	8%	0.078	C	C	.	.	G	3₁₀ helix	trans	-55.7	-40.7	172.1	0	0	0	0	0	111.5	A340 G402 V403 I410	A340-A405 HydrophobicContact CB-CB 3.88Å; G402-A405 WeakPolarHBondContact O-CB 3.37Å; G402-A405 PolarHBondContact O-N 3.39Å; V403-A405 PolarHBondContact O-N 3.2Å; A405-I410 WeakPolarHBondContact O-CD1 3.33Å; A405-I410 WeakPolarHBondContact O-CG1 3.28Å
406	S	87.5	Confident	89.8	Confident	1 Å²	1	11.6 Å²	11.6	1%	0.007	7%	0.069	C	C	.	.	G	3₁₀ helix	trans	-88.9	-3.9	177.2	-57.9	0	0	0	0	113.8	S343 G344 R362 V403 S404	S343-S406 PolarHBondContact O-OG 3.38Å; S343-S406 PolarHBondContact OG-OG 3.16Å; G344-S406 WeakPolarHBondContact CA-OG 2.82Å; G344-S406 PolarHBondContact N-OG 3.3Å; R362-S406 WeakPolarHBondContact CD-O 3.22Å; R362-S406 PolarHBondContact NH1-O 3.04Å; V403-S406 PolarHBondContact O-N 2.99Å; V403-S406 VanDerWaalsContact O-N 3.15Å; S404-S406 PolarHBondContact O-N 2.84Å
407	G	90.8	Very high	89	Confident	0 Å²	0	9.1 Å²	9.1	0%	0	6%	0.057	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90.9	-114.5	176.3	0	0	0	0	0	112.2	R362 S366 S404 N409	R362-G407 VanDerWaalsContact CD-O 3.22Å; R362-G407 WeakPolarHBondContact CD-O 3.36Å; S366-G407 VanDerWaalsContact OG-CA 3.22Å; S366-G407 WeakPolarHBondContact OG-CA 3.49Å; S404-G407 WeakPolarHBondContact O-CA 3.4Å; S404-G407 PolarHBondContact O-N 3.31Å; G407-N409 PolarHBondContact O-N 2.88Å
408	F	90.8	Very high	88.2	Confident	0 Å²	0	11 Å²	11	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-68.6	-28	-173.6	77.8	-94.5	0	0	0	114.1	I292 A295 H296 Y299 S366 I410 N411 Y472	I292-F408 HydrophobicContact CG2-CD2 4.32Å; A295-F408 HydrophobicContact CB-CB 4.02Å; A295-F408 HydrophobicContact CB-CD1 4.08Å; A295-F408 HydrophobicContact CB-CD2 4.23Å; A295-F408 HydrophobicContact CB-CG 3.83Å; H296-F408 HydrophobicContact CB-CD2 4.19Å; H296-F408 HydrophobicContact CB-CE2 3.65Å; H296-F408 HydrophobicContact CB-CZ 4.41Å; H296-F408 AromaticContact CD2-CE2 3.55Å; H296-F408 AromaticContact CD2-CZ 3.97Å; H296-F408 AromaticContact CG-CE2 3.75Å; Y299-F408 HydrophobicContact CD1-CE1 4.49Å; Y299-F408 HydrophobicContact CD1-CZ 4.01Å; Y299-F408 HydrophobicContact CD2-CE1 4.29Å; Y299-F408 AromaticContact CG-CE1 3.92Å; Y299-F408 HydrophobicContact CG-CE1 3.92Å; Y299-F408 AromaticContact CG-CZ 3.85Å; Y299-F408 HydrophobicContact CG-CZ 3.85Å; S366-F408 PolarHBondContact OG-N 3.47Å; F408-I410 PolarHBondContact O-N 3.15Å; F408-N411 WeakPolarHBondContact O-CB 3.4Å; F408-N411 PolarHBondContact O-N 3.49Å; F408-Y472 WeakPolarHBondContact CA-OH 3.46Å; F408-Y472 HydrophobicContact CB-CD2 4.18Å; F408-Y472 HydrophobicContact CB-CE1 4.14Å; F408-Y472 HydrophobicContact CB-CE2 3.69Å
409	N	86.9	Confident	87.7	Confident	33 Å²	33	11.8 Å²	11.8	18%	0.176	7%	0.071	C	C	.	.	H	α-helix	trans	-61.1	-41.5	-172.2	-88.1	-44	0	0	0	113.3	Y180 G407 N411 H412	Y180-N409 PolarHBondContact OH-O 3.02Å; Y180-N409 VanDerWaalsContact OH-O 3.13Å; G407-N409 PolarHBondContact O-N 2.88Å; N409-N411 VanDerWaalsContact C-N 3.29Å; N409-N411 PolarHBondContact O-N 2.83Å; N409-H412 PolarHBondContact O-ND1 2.92Å
410	I	86.3	Confident	87.1	Confident	7 Å²	7	11.1 Å²	11.1	4%	0.036	7%	0.065	C	C	.	.	H	α-helix	trans	-78.1	-17.1	178.2	-62.1	166.7	0	0	0	111.6	L196 R362 A405 F408 H412 L413	L196-I410 HydrophobicContact CD1-CG1 4.44Å; L196-I410 HydrophobicContact CD1-CG2 4.36Å; R362-I410 VanDerWaalsContact NH2-CG2 3.3Å; A405-I410 WeakPolarHBondContact O-CD1 3.33Å; A405-I410 WeakPolarHBondContact O-CG1 3.28Å; F408-I410 PolarHBondContact O-N 3.15Å; I410-H412 PolarHBondContact O-N 3.02Å; I410-H412 VanDerWaalsContact O-N 3.09Å; I410-L413 PolarHBondContact O-N 3.09Å
411	N	90.3	Very high	86.4	Confident	0 Å²	0	9.2 Å²	9.2	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-62.8	-26	-170.4	-163.4	18.3	0	0	0	113.8	I292 F408 N409 L413 D414 I415 Y472 R477	I292-N411 HydrophobicContact CD1-CB 3.93Å; I292-N411 HydrophobicContact CG1-CB 4.24Å; F408-N411 WeakPolarHBondContact O-CB 3.4Å; F408-N411 PolarHBondContact O-N 3.49Å; N409-N411 VanDerWaalsContact C-N 3.29Å; N409-N411 PolarHBondContact O-N 2.83Å; N411-L413 PolarHBondContact O-N 3.43Å; N411-L413 VanDerWaalsContact O-N 3.16Å; N411-D414 PolarHBondContact O-N 3.06Å; N411-I415 WeakPolarHBondContact O-CG1 3.03Å; N411-I415 PolarHBondContact O-N 3.44Å; N411-Y472 WeakPolarHBondContact CB-OH 3.45Å; N411-Y472 PolarHBondContact ND2-OH 3.26Å; N411-R477 VanDerWaalsContact CG-O 3.28Å; N411-R477 PolarHBondContact ND2-O 2.92Å; N411-R477 PolarHBondContact OD1-O 3.25Å
412	H	88.3	Confident	86.1	Confident	0 Å²	0	9.9 Å²	9.9	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-50.5	-40.2	172.5	-56.7	89.2	0	0	0	112.5	Y180 I292 N409 I410 I415 A416 T427	Y180-H412 HydrophobicContact CE1-CB 4.26Å; I292-H412 WeakPolarHBondContact CG2-CE1 3.41Å; I292-H412 WeakPolarHBondContact CG2-NE2 3.23Å; N409-H412 PolarHBondContact O-ND1 2.92Å; I410-H412 PolarHBondContact O-N 3.02Å; I410-H412 VanDerWaalsContact O-N 3.09Å; H412-I415 WeakPolarHBondContact O-CG1 3.35Å; H412-A416 PolarHBondContact O-N 3.18Å; H412-T427 WeakPolarHBondContact NE2-CB 3.4Å; H412-T427 VanDerWaalsContact NE2-CG2 3.29Å; H412-T427 WeakPolarHBondContact NE2-CG2 3.24Å; H412-T427 PolarHBondContact NE2-OG1 2.98Å
413	L	82.9	Confident	86	Confident	2 Å²	2	9.8 Å²	9.8	1%	0.01	6%	0.058	C	C	.	.	H	α-helix	trans	-84.4	-19.3	-178.9	-71	154.9	0	0	0	113	Y180 R192 L196 I410 N411 P417 A420	Y180-L413 HydrophobicContact CD1-CD1 3.89Å; Y180-L413 HydrophobicContact CD1-CD2 4.44Å; Y180-L413 HydrophobicContact CD1-CG 4.08Å; Y180-L413 HydrophobicContact CE1-CD1 3.68Å; Y180-L413 HydrophobicContact CE1-CG 4.09Å; R192-L413 HydrophobicContact CG-CD1 4.12Å; L196-L413 HydrophobicContact CD1-CD1 3.22Å; L196-L413 HydrophobicContact CD2-CD1 3.95Å; L196-L413 HydrophobicContact CG-CD1 4.17Å; I410-L413 PolarHBondContact O-N 3.09Å; N411-L413 PolarHBondContact O-N 3.43Å; N411-L413 VanDerWaalsContact O-N 3.16Å; L413-P417 WeakPolarHBondContact O-CG 3.36Å; L413-A420 HydrophobicContact CD2-CB 3.31Å; L413-A420 HydrophobicContact CG-CB 3.92Å
414	D	85.2	Confident	85.8	Confident	28 Å²	28	9.5 Å²	9.5	15%	0.15	6%	0.056	C	C	.	.	H	α-helix	trans	-78.2	-32.4	173.4	-64.9	-35.5	0	0	0	110.5	R362 N411 T479 V480	R362-D414 IonicContact CZ-OD2 3.37Å; R362-D414 IonicContact NE-OD2 2.77Å; R362-D414 PolarHBondContact NE-OD2 3.21Å; R362-D414 IonicContact NH2-OD1 3.62Å; R362-D414 IonicContact NH2-OD2 3.11Å; R362-D414 PolarHBondContact NH2-OD2 3.41Å; R362-D414 VanDerWaalsContact NH2-OD2 3.11Å; N411-D414 PolarHBondContact O-N 3.06Å; D414-T479 CarbonylContact O-C 3.55Å; D414-V480 PolarHBondContact O-N 3.05Å
415	I	87.9	Confident	85.6	Confident	0 Å²	0	9.5 Å²	9.5	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-88.2	-36.9	-177.2	65.5	165.4	0	0	0	114.5	I292 N411 H412 L423 V480 Q481	I292-I415 HydrophobicContact CD1-CD1 3.58Å; I292-I415 HydrophobicContact CD1-CG1 4.25Å; N411-I415 WeakPolarHBondContact O-CG1 3.03Å; N411-I415 PolarHBondContact O-N 3.44Å; H412-I415 WeakPolarHBondContact O-CG1 3.35Å; I415-L423 HydrophobicContact CD1-CD2 3.48Å; I415-L423 VanDerWaalsContact CD1-CD2 3.48Å; I415-L423 HydrophobicContact CG1-CD2 3.59Å; I415-V480 WeakPolarHBondContact O-CA 3.02Å; I415-Q481 HydrophobicContact CB-CG 3.99Å; I415-Q481 PolarHBondContact O-N 3.12Å
416	A	85.7	Confident	85.9	Confident	0 Å²	0	9 Å²	9	0%	0	5%	0.05	C	C	.	.			trans	-157.1	80.5	-179.6	0	0	0	0	0	112	H412 S418 Y419 A420 L423 W483 A484	H412-A416 PolarHBondContact O-N 3.18Å; A416-S418 VanDerWaalsContact C-N 3.29Å; A416-S418 PolarHBondContact O-N 3.17Å; A416-Y419 HydrophobicContact CB-CD2 4.44Å; A416-Y419 CarbonylContact O-C 3.56Å; A416-Y419 PolarHBondContact O-N 3.31Å; A416-Y419 VanDerWaalsContact O-N 3.14Å; A416-A420 PolarHBondContact O-N 3.02Å; A416-A420 VanDerWaalsContact O-N 3.07Å; A416-L423 HydrophobicContact CB-CD1 4.32Å; A416-L423 HydrophobicContact CB-CD2 3.83Å; A416-W483 HydrophobicContact CB-CH2 3.4Å; A416-W483 HydrophobicContact CB-CZ2 4.43Å; A416-W483 HydrophobicContact CB-CZ3 3.51Å; A416-A484 HydrophobicContact CB-CB 3.63Å
417	P	77.3	Confident	86.2	Confident	8 Å²	8	8.9 Å²	8.9	5%	0.052	5%	0.049	C	C	.	.	G	3₁₀ helix	trans	-51.5	-45.5	179.4	-22.5	27	0	0	0	113.5	E270 L413 Y419 A420	E270-P417 WeakPolarHBondContact OE2-CB 3.33Å; E270-P417 WeakPolarHBondContact OE2-CG 3.5Å; L413-P417 WeakPolarHBondContact O-CG 3.36Å; P417-Y419 PolarHBondContact O-N 3.43Å; P417-A420 VanDerWaalsContact O-CB 3.31Å; P417-A420 WeakPolarHBondContact O-CB 3.39Å; P417-A420 PolarHBondContact O-N 3.34Å
418	S	78.3	Confident	86.2	Confident	38 Å²	38	9.2 Å²	9.2	27%	0.266	5%	0.051	S	C	.	.	G	3₁₀ helix	trans	-67.7	-21	-175.2	-31.9	0	0	0	0	113.6	E270 A416	E270-S418 PolarHBondContact O-OG 3.02Å; A416-S418 VanDerWaalsContact C-N 3.29Å; A416-S418 PolarHBondContact O-N 3.17Å
419	Y	82.4	Confident	86.3	Confident	33 Å²	33	10 Å²	10	13%	0.129	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-114.8	11.6	-179.8	-61.4	-68.2	0	0	0	112.2	I278 A416 P417 G421 I422 L423 W483 A484	I278-Y419 HydrophobicContact CG1-CE1 4.35Å; I278-Y419 HydrophobicContact CG2-CE1 4.41Å; A416-Y419 HydrophobicContact CB-CD2 4.44Å; A416-Y419 CarbonylContact O-C 3.56Å; A416-Y419 PolarHBondContact O-N 3.31Å; A416-Y419 VanDerWaalsContact O-N 3.14Å; P417-Y419 PolarHBondContact O-N 3.43Å; Y419-G421 VanDerWaalsContact C-N 3.3Å; Y419-G421 PolarHBondContact O-N 3.47Å; Y419-I422 HydrophobicContact CD1-CD1 4.26Å; Y419-I422 WeakPolarHBondContact O-CB 3.45Å; Y419-I422 PolarHBondContact O-N 3.09Å; Y419-L423 VanDerWaalsContact O-CD1 3.24Å; Y419-L423 WeakPolarHBondContact O-CD1 3.28Å; Y419-L423 PolarHBondContact O-N 2.9Å; Y419-W483 HydrophobicContact CD2-CE3 4.32Å; Y419-W483 AromaticContact CD2-CZ3 3.88Å; Y419-W483 HydrophobicContact CD2-CZ3 3.88Å; Y419-A484 HydrophobicContact CD2-CB 4.47Å
420	A	80.8	Confident	86.6	Confident	1 Å²	1	13 Å²	13	1%	0.008	7%	0.068	C	C	.	.	H	α-helix	trans	-58.4	-37.8	-167.9	0	0	0	0	0	113.8	Y180 L413 A416 P417 L423 L424	Y180-A420 HydrophobicContact CD1-CB 4.29Å; L413-A420 HydrophobicContact CD2-CB 3.31Å; L413-A420 HydrophobicContact CG-CB 3.92Å; A416-A420 PolarHBondContact O-N 3.02Å; A416-A420 VanDerWaalsContact O-N 3.07Å; P417-A420 VanDerWaalsContact O-CB 3.31Å; P417-A420 WeakPolarHBondContact O-CB 3.39Å; P417-A420 PolarHBondContact O-N 3.34Å; A420-L423 PolarHBondContact O-N 3.04Å; A420-L424 WeakPolarHBondContact O-CB 3.43Å; A420-L424 PolarHBondContact O-N 2.9Å
421	G	79.6	Confident	86.8	Confident	4 Å²	4	12.7 Å²	12.7	4%	0.041	7%	0.066	C	C	.	.	H	α-helix	trans	-63.8	-39.3	174.7	0	0	0	0	0	113.4	Y419 G425	Y419-G421 VanDerWaalsContact C-N 3.3Å; Y419-G421 PolarHBondContact O-N 3.47Å; G421-G425 PolarHBondContact O-N 3.24Å
422	I	86.1	Confident	86.8	Confident	17 Å²	17	12.7 Å²	12.7	9%	0.087	7%	0.066	C	C	.	.	H	α-helix	trans	-69.3	-45.8	175.9	-61.4	177.1	0	0	0	110.2	I278 W280 Y419 L424 G425 I426	I278-I422 HydrophobicContact CD1-CD1 3.81Å; I278-I422 HydrophobicContact CG1-CD1 4.44Å; I278-I422 HydrophobicContact CG2-CD1 4.3Å; W280-I422 HydrophobicContact CH2-CG2 3.95Å; W280-I422 HydrophobicContact CZ3-CG2 3.94Å; Y419-I422 HydrophobicContact CD1-CD1 4.26Å; Y419-I422 WeakPolarHBondContact O-CB 3.45Å; Y419-I422 PolarHBondContact O-N 3.09Å; I422-L424 PolarHBondContact O-N 2.87Å; I422-G425 PolarHBondContact O-N 3.33Å; I422-I426 HydrophobicContact CG2-CD1 4.02Å; I422-I426 WeakPolarHBondContact O-CG1 3.42Å; I422-I426 PolarHBondContact O-N 3.47Å
423	L	89.8	Confident	86.8	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-58.4	-48.6	178.5	-93	68.1	0	0	0	111.1	I283 L289 I415 A416 Y419 A420 I426 T427 W483	I283-L423 HydrophobicContact CG2-CD1 4.26Å; L289-L423 HydrophobicContact CD1-CB 4.34Å; L289-L423 HydrophobicContact CD1-CD2 4.29Å; L289-L423 HydrophobicContact CD1-CG 3.94Å; I415-L423 HydrophobicContact CD1-CD2 3.48Å; I415-L423 VanDerWaalsContact CD1-CD2 3.48Å; I415-L423 HydrophobicContact CG1-CD2 3.59Å; A416-L423 HydrophobicContact CB-CD1 4.32Å; A416-L423 HydrophobicContact CB-CD2 3.83Å; Y419-L423 VanDerWaalsContact O-CD1 3.24Å; Y419-L423 WeakPolarHBondContact O-CD1 3.28Å; Y419-L423 PolarHBondContact O-N 2.9Å; A420-L423 PolarHBondContact O-N 3.04Å; L423-I426 PolarHBondContact O-N 2.88Å; L423-T427 VanDerWaalsContact O-CG2 3.26Å; L423-T427 WeakPolarHBondContact O-CG2 3.43Å; L423-T427 PolarHBondContact O-N 3.14Å; L423-T427 PolarHBondContact O-OG1 3.37Å; L423-W483 HydrophobicContact CD1-CH2 3.97Å; L423-W483 HydrophobicContact CD1-CZ3 4.32Å; L423-W483 HydrophobicContact CD2-CH2 4.15Å; L423-W483 HydrophobicContact CG-CH2 4.48Å
424	L	88.1	Confident	87	Confident	4 Å²	4	15.3 Å²	15.3	2%	0.021	8%	0.079	C	C	.	.	H	α-helix	trans	-62.9	-43.6	175.3	-172.9	82.6	0	0	0	111.2	F176 Y180 A420 I422 I426 T427 N428	F176-L424 HydrophobicContact CB-CD2 3.77Å; Y180-L424 HydrophobicContact CD1-CB 4.3Å; Y180-L424 HydrophobicContact CD1-CD2 4.38Å; Y180-L424 HydrophobicContact CD2-CB 4.44Å; Y180-L424 HydrophobicContact CD2-CD1 4.25Å; Y180-L424 HydrophobicContact CD2-CD2 3.12Å; Y180-L424 HydrophobicContact CD2-CG 4.09Å; Y180-L424 HydrophobicContact CE1-CD1 4.15Å; Y180-L424 HydrophobicContact CE2-CD1 3.73Å; Y180-L424 HydrophobicContact CE2-CD2 3.38Å; Y180-L424 HydrophobicContact CE2-CG 4.07Å; Y180-L424 HydrophobicContact CG-CB 4.22Å; Y180-L424 HydrophobicContact CG-CD2 3.66Å; Y180-L424 HydrophobicContact CG-CG 4.37Å; A420-L424 WeakPolarHBondContact O-CB 3.43Å; A420-L424 PolarHBondContact O-N 2.9Å; I422-L424 PolarHBondContact O-N 2.87Å; L424-I426 VanDerWaalsContact C-N 3.27Å; L424-I426 PolarHBondContact O-N 3.1Å; L424-T427 PolarHBondContact O-N 3.12Å; L424-T427 PolarHBondContact O-OG1 3.26Å; L424-N428 WeakPolarHBondContact O-CA 3.35Å; L424-N428 WeakPolarHBondContact O-CB 3.26Å; L424-N428 PolarHBondContact O-N 3.38Å
425	G	87.3	Confident	86.7	Confident	0 Å²	0	14 Å²	14	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-53.3	-46.8	175.6	0	0	0	0	0	111.6	G421 I422 T429	G421-G425 PolarHBondContact O-N 3.24Å; I422-G425 PolarHBondContact O-N 3.33Å; G425-T429 WeakPolarHBondContact O-CB 3.36Å; G425-T429 PolarHBondContact O-N 2.75Å; G425-T429 PolarHBondContact O-OG1 3.21Å
426	I	92.1	Very high	86.4	Confident	12 Å²	12	15.2 Å²	15.2	6%	0.062	8%	0.079	C	C	.	.	H	α-helix	trans	-61.9	-54.7	175.5	-65	166.2	0	0	0	110.9	W280 I283 I422 L423 L424 N428 T429 F430	W280-I426 HydrophobicContact CZ3-CD1 4.28Å; I283-I426 HydrophobicContact CG2-CD1 4.07Å; I422-I426 HydrophobicContact CG2-CD1 4.02Å; I422-I426 WeakPolarHBondContact O-CG1 3.42Å; I422-I426 PolarHBondContact O-N 3.47Å; L423-I426 PolarHBondContact O-N 2.88Å; L424-I426 VanDerWaalsContact C-N 3.27Å; L424-I426 PolarHBondContact O-N 3.1Å; I426-N428 PolarHBondContact O-N 3.46Å; I426-T429 WeakPolarHBondContact O-CB 3.17Å; I426-T429 PolarHBondContact O-N 2.81Å; I426-F430 HydrophobicContact CG2-CD2 4.26Å; I426-F430 HydrophobicContact CG2-CE2 4.05Å; I426-F430 VanDerWaalsContact O-CD2 3.26Å; I426-F430 WeakPolarHBondContact O-CD2 3.3Å; I426-F430 PolarHBondContact O-N 3.24Å
427	T	93.6	Very high	86.2	Confident	0 Å²	0	18 Å²	18	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-66	-39.2	-174.4	67.6	0	0	0	0	112.2	L289 I292 V293 H296 H412 L423 L424 T429 F430 A431	L289-T427 HydrophobicContact CD1-CG2 3.65Å; I292-T427 HydrophobicContact CB-CG2 4.45Å; I292-T427 HydrophobicContact CG2-CG2 4.02Å; V293-T427 HydrophobicContact CG2-CG2 3.62Å; H296-T427 PolarHBondContact ND1-OG1 3.19Å; H412-T427 WeakPolarHBondContact NE2-CB 3.4Å; H412-T427 VanDerWaalsContact NE2-CG2 3.29Å; H412-T427 WeakPolarHBondContact NE2-CG2 3.24Å; H412-T427 PolarHBondContact NE2-OG1 2.98Å; L423-T427 VanDerWaalsContact O-CG2 3.26Å; L423-T427 WeakPolarHBondContact O-CG2 3.43Å; L423-T427 PolarHBondContact O-N 3.14Å; L423-T427 PolarHBondContact O-OG1 3.37Å; L424-T427 PolarHBondContact O-N 3.12Å; L424-T427 PolarHBondContact O-OG1 3.26Å; T427-T429 VanDerWaalsContact C-N 3.35Å; T427-F430 PolarHBondContact O-N 2.6Å; T427-A431 VanDerWaalsContact O-CB 3.22Å; T427-A431 WeakPolarHBondContact O-CB 3.46Å; T427-A431 PolarHBondContact O-N 3.32Å
428	N	91.5	Very high	86.3	Confident	6 Å²	6	17.7 Å²	17.7	3%	0.032	9%	0.094	C	C	.	.	H	α-helix	trans	-68.2	-34.2	178.6	-160	37.8	0	0	0	111.5	Y116 Q120 L424 I426 A431 T432	Y116-N428 PolarHBondContact OH-ND2 3.38Å; Q120-N428 PolarHBondContact NE2-ND2 3.47Å; Q120-N428 PolarHBondContact OE1-ND2 2.92Å; L424-N428 WeakPolarHBondContact O-CA 3.35Å; L424-N428 WeakPolarHBondContact O-CB 3.26Å; L424-N428 PolarHBondContact O-N 3.38Å; I426-N428 PolarHBondContact O-N 3.46Å; N428-A431 CarbonylContact O-C 3.59Å; N428-A431 PolarHBondContact O-N 3.29Å; N428-T432 WeakPolarHBondContact O-CG2 3.31Å; N428-T432 PolarHBondContact O-N 3.32Å; N428-T432 PolarHBondContact O-OG1 2.93Å
429	T	91.9	Very high	86	Confident	18 Å²	18	16.9 Å²	16.9	11%	0.11	9%	0.087	C	C	.	.	H	α-helix	trans	-54.8	-56	171.6	-59.1	0	0	0	0	110.4	I117 Q120 I121 G425 I426 T427 A431 T432	I117-T429 HydrophobicContact CD1-CG2 3.99Å; I117-T429 HydrophobicContact CG1-CG2 3.51Å; Q120-T429 WeakPolarHBondContact CB-OG1 3.26Å; I121-T429 HydrophobicContact CD1-CG2 4.25Å; I121-T429 HydrophobicContact CG1-CG2 4.41Å; I121-T429 VanDerWaalsContact CG1-OG1 3.22Å; I121-T429 WeakPolarHBondContact CG1-OG1 3.45Å; G425-T429 WeakPolarHBondContact O-CB 3.36Å; G425-T429 PolarHBondContact O-N 2.75Å; G425-T429 PolarHBondContact O-OG1 3.21Å; I426-T429 WeakPolarHBondContact O-CB 3.17Å; I426-T429 PolarHBondContact O-N 2.81Å; T427-T429 VanDerWaalsContact C-N 3.35Å; T429-A431 VanDerWaalsContact C-N 3.29Å; T429-A431 PolarHBondContact O-N 3.22Å; T429-T432 PolarHBondContact O-N 3.45Å; T429-T432 PolarHBondContact O-OG1 3.14Å
430	F	93.1	Very high	85.8	Confident	96 Å²	96	19.6 Å²	19.6	42%	0.421	11%	0.107	S	C	.	.	H	α-helix	trans	-63	-39	177.3	-71.1	-75.2	0	0	0	111.7	V293 F297 I426 T427 T432 I433 P434	V293-F430 HydrophobicContact CG1-CB 3.8Å; V293-F430 HydrophobicContact CG1-CD2 3.9Å; V293-F430 HydrophobicContact CG1-CG 3.88Å; F297-F430 WeakPolarHBondContact CD2-O 3.37Å; I426-F430 HydrophobicContact CG2-CD2 4.26Å; I426-F430 HydrophobicContact CG2-CE2 4.05Å; I426-F430 VanDerWaalsContact O-CD2 3.26Å; I426-F430 WeakPolarHBondContact O-CD2 3.3Å; I426-F430 PolarHBondContact O-N 3.24Å; T427-F430 PolarHBondContact O-N 2.6Å; F430-T432 PolarHBondContact O-N 2.87Å; F430-I433 HydrophobicContact CD1-CD1 3.99Å; F430-I433 WeakPolarHBondContact O-CB 3.11Å; F430-I433 WeakPolarHBondContact O-CG1 3.27Å; F430-I433 PolarHBondContact O-N 2.87Å; F430-P434 WeakPolarHBondContact O-CD 3.37Å
431	A	91.4	Very high	85.8	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-70.8	-10.1	-178.8	0	0	0	0	0	114.8	H296 N300 Y304 T427 N428 T429 P434	H296-A431 HydrophobicContact CB-CB 3.98Å; H296-A431 VanDerWaalsContact CG-CB 3.43Å; N300-A431 HydrophobicContact CB-CB 4.26Å; N300-A431 WeakPolarHBondContact CB-O 3.05Å; N300-A431 WeakPolarHBondContact ND2-CB 3.47Å; Y304-A431 WeakPolarHBondContact CE2-O 3.16Å; T427-A431 VanDerWaalsContact O-CB 3.22Å; T427-A431 WeakPolarHBondContact O-CB 3.46Å; T427-A431 PolarHBondContact O-N 3.32Å; N428-A431 CarbonylContact O-C 3.59Å; N428-A431 PolarHBondContact O-N 3.29Å; T429-A431 VanDerWaalsContact C-N 3.29Å; T429-A431 PolarHBondContact O-N 3.22Å; A431-P434 WeakPolarHBondContact O-CD 3.4Å
432	T	89.1	Confident	85.7	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-90.2	-18.9	174.4	58	0	0	0	0	114	Y116 N428 T429 F430 P434 G435 M436	Y116-T432 HydrophobicContact CD1-CG2 3.32Å; Y116-T432 HydrophobicContact CE1-CG2 3.27Å; N428-T432 WeakPolarHBondContact O-CG2 3.31Å; N428-T432 PolarHBondContact O-N 3.32Å; N428-T432 PolarHBondContact O-OG1 2.93Å; T429-T432 PolarHBondContact O-N 3.45Å; T429-T432 PolarHBondContact O-OG1 3.14Å; F430-T432 PolarHBondContact O-N 2.87Å; T432-P434 VanDerWaalsContact C-CD 3.44Å; T432-P434 VanDerWaalsContact C-N 3.32Å; T432-G435 WeakPolarHBondContact O-CA 3.47Å; T432-G435 PolarHBondContact O-N 3.08Å; T432-M436 PolarHBondContact O-N 2.95Å
433	I	89.4	Confident	85	Confident	56 Å²	56	25.6 Å²	25.6	29%	0.287	13%	0.132	S	C	.	.	H	α-helix	trans	-53.6	-43.1	175.4	-60.5	171.5	0	0	0	112	I117 F297 F430 G435 M436 V437	I117-I433 HydrophobicContact CD1-CG1 3.89Å; F297-I433 HydrophobicContact CE2-CB 4.24Å; F297-I433 HydrophobicContact CE2-CG2 4.33Å; F430-I433 HydrophobicContact CD1-CD1 3.99Å; F430-I433 WeakPolarHBondContact O-CB 3.11Å; F430-I433 WeakPolarHBondContact O-CG1 3.27Å; F430-I433 PolarHBondContact O-N 2.87Å; I433-G435 PolarHBondContact O-N 3.31Å; I433-M436 WeakPolarHBondContact O-CB 3.27Å; I433-M436 PolarHBondContact O-N 3.49Å; I433-V437 HydrophobicContact CG2-CG2 3.96Å; I433-V437 PolarHBondContact O-N 3.34Å
434	P	86.9	Confident	84.5	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-57.8	-31.2	174	-23.4	32.3	0	0	0	114.7	F297 W301 F430 A431 T432 M436 G438	F297-P434 HydrophobicContact CD2-CG 3.63Å; F297-P434 HydrophobicContact CE1-CG 4.44Å; F297-P434 HydrophobicContact CE2-CG 3.55Å; F297-P434 HydrophobicContact CG-CG 4.12Å; F297-P434 HydrophobicContact CZ-CG 3.98Å; W301-P434 VanDerWaalsContact CA-CB 3.47Å; W301-P434 HydrophobicContact CB-CB 3.94Å; W301-P434 HydrophobicContact CB-CG 4.24Å; W301-P434 HydrophobicContact CD2-CB 4.12Å; W301-P434 HydrophobicContact CE3-CB 3.55Å; W301-P434 HydrophobicContact CE3-CG 3.93Å; W301-P434 HydrophobicContact CG-CB 4.34Å; W301-P434 HydrophobicContact CZ3-CB 4.33Å; F430-P434 WeakPolarHBondContact O-CD 3.37Å; A431-P434 WeakPolarHBondContact O-CD 3.4Å; T432-P434 VanDerWaalsContact C-CD 3.44Å; T432-P434 VanDerWaalsContact C-N 3.32Å; P434-M436 VanDerWaalsContact C-N 3.26Å; P434-M436 PolarHBondContact O-N 3.28Å; P434-G438 VanDerWaalsContact O-CA 3.22Å; P434-G438 WeakPolarHBondContact O-CA 3.48Å; P434-G438 PolarHBondContact O-N 3.32Å
435	G	78.1	Confident	84.2	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-68.9	-25.8	175.5	0	0	0	0	0	113.1	F113 T432 I433 P439	F113-G435 WeakPolarHBondContact CD2-O 3.3Å; F113-G435 WeakPolarHBondContact CE2-O 3.23Å; T432-G435 WeakPolarHBondContact O-CA 3.47Å; T432-G435 PolarHBondContact O-N 3.08Å; I433-G435 PolarHBondContact O-N 3.31Å; G435-P439 VanDerWaalsContact O-CD 3.28Å; G435-P439 WeakPolarHBondContact O-CD 3.47Å; G435-P439 WeakPolarHBondContact O-CG 3.32Å
436	M	81.4	Confident	83.6	Confident	27 Å²	27	32.8 Å²	32.8	13%	0.133	18%	0.181	C	C	.	.	H	α-helix	trans	-83.4	-47.3	176.3	-56.4	169.1	67.7	0	0	111.6	F113 Y114 I117 T432 I433 P434	F113-M436 HydrophobicContact CB-CG 3.37Å; F113-M436 HydrophobicContact CB-SD 4.44Å; F113-M436 HydrophobicContact CG-CG 4.31Å; Y114-M436 HydrophobicContact CD1-CE 3.14Å; Y114-M436 HydrophobicContact CD2-CE 4.16Å; Y114-M436 HydrophobicContact CE1-CE 3.14Å; Y114-M436 HydrophobicContact CE2-CE 4.2Å; Y114-M436 HydrophobicContact CG-CE 3.68Å; I117-M436 HydrophobicContact CD1-SD 4.12Å; I117-M436 HydrophobicContact CG2-SD 4.41Å; T432-M436 PolarHBondContact O-N 2.95Å; I433-M436 WeakPolarHBondContact O-CB 3.27Å; I433-M436 PolarHBondContact O-N 3.49Å; P434-M436 VanDerWaalsContact C-N 3.26Å; P434-M436 PolarHBondContact O-N 3.28Å
437	V	82.3	Confident	82.7	Confident	59 Å²	59	39.7 Å²	39.7	36%	0.358	21%	0.213	S	C	.	.	H	α-helix	trans	-89.8	-34	-169.8	-178.6	0	0	0	0	111.8	I433 V440 I441	I433-V437 HydrophobicContact CG2-CG2 3.96Å; I433-V437 PolarHBondContact O-N 3.34Å; V437-V440 PolarHBondContact O-N 2.79Å; V437-I441 HydrophobicContact CG1-CD1 3.44Å; V437-I441 VanDerWaalsContact CG1-CD1 3.44Å; V437-I441 HydrophobicContact CG1-CG1 3.89Å; V437-I441 WeakPolarHBondContact O-CG1 3.28Å; V437-I441 PolarHBondContact O-N 3.43Å
438	G	79.2	Confident	81.6	Confident	1 Å²	1	45.1 Å²	45.1	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-56.7	-52.5	-176.4	0	0	0	0	0	113.6	P434 V440 I441 A442	P434-G438 VanDerWaalsContact O-CA 3.22Å; P434-G438 WeakPolarHBondContact O-CA 3.48Å; P434-G438 PolarHBondContact O-N 3.32Å; G438-V440 VanDerWaalsContact C-N 3.3Å; G438-V440 PolarHBondContact O-N 2.91Å; G438-I441 PolarHBondContact O-N 2.75Å; G438-A442 WeakPolarHBondContact O-CB 3.4Å; G438-A442 PolarHBondContact O-N 2.9Å
439	P	72.5	Confident	80.6	Confident	21 Å²	21	47.8 Å²	47.8	14%	0.136	26%	0.256	C	S	.	.	H	α-helix	trans	-60.8	-38	178.2	-24.5	34.4	0	0	0	113.2	T308 G435 R443	T308-P439 HydrophobicContact CG2-CG 4.11Å; G435-P439 VanDerWaalsContact O-CD 3.28Å; G435-P439 WeakPolarHBondContact O-CD 3.47Å; G435-P439 WeakPolarHBondContact O-CG 3.32Å; P439-R443 VanDerWaalsContact O-CB 3.28Å; P439-R443 WeakPolarHBondContact O-CB 3.34Å; P439-R443 PolarHBondContact O-N 2.87Å
440	V	77.9	Confident	80	Confident	89 Å²	89	49.6 Å²	49.6	54%	0.539	27%	0.267	S	S	.	.	H	α-helix	trans	-65.9	-47.7	178.7	179	0	0	0	0	110.6	V437 G438 A444	V437-V440 PolarHBondContact O-N 2.79Å; G438-V440 VanDerWaalsContact C-N 3.3Å; G438-V440 PolarHBondContact O-N 2.91Å; V440-A444 WeakPolarHBondContact O-CB 3.42Å; V440-A444 PolarHBondContact O-N 3.36Å
441	I	80.9	Confident	79.3	Confident	63 Å²	63	47.1 Å²	47.1	32%	0.323	26%	0.258	S	S	.	.	H	α-helix	trans	-64.7	-47.5	178.4	-71.2	-178.4	0	0	0	110.7	W301 V437 G438 R443 A444 L445	W301-I441 HydrophobicContact CH2-CD1 4.01Å; V437-I441 HydrophobicContact CG1-CD1 3.44Å; V437-I441 VanDerWaalsContact CG1-CD1 3.44Å; V437-I441 HydrophobicContact CG1-CG1 3.89Å; V437-I441 WeakPolarHBondContact O-CG1 3.28Å; V437-I441 PolarHBondContact O-N 3.43Å; G438-I441 PolarHBondContact O-N 2.75Å; I441-R443 VanDerWaalsContact C-N 3.33Å; I441-R443 PolarHBondContact O-N 3.47Å; I441-A444 PolarHBondContact O-N 3.38Å; I441-L445 HydrophobicContact CG2-CD1 3.72Å; I441-L445 HydrophobicContact CG2-CG 4.34Å; I441-L445 VanDerWaalsContact O-CG 3.27Å; I441-L445 WeakPolarHBondContact O-CG 3.38Å; I441-L445 PolarHBondContact O-N 3.27Å
442	A	76.8	Confident	78.9	Confident	3 Å²	3	53.7 Å²	53.7	3%	0.025	29%	0.289	C	S	.	.	H	α-helix	trans	-60.3	-45.2	-179.2	0	0	0	0	0	111.2	L309 G438 A444 L445 T446 V457	L309-A442 HydrophobicContact CD1-CB 3.15Å; L309-A442 HydrophobicContact CG-CB 4.45Å; G438-A442 WeakPolarHBondContact O-CB 3.4Å; G438-A442 PolarHBondContact O-N 2.9Å; A442-A444 VanDerWaalsContact C-N 3.34Å; A442-A444 PolarHBondContact O-N 3.06Å; A442-L445 CarbonylContact O-C 3.56Å; A442-L445 PolarHBondContact O-N 3.37Å; A442-L445 VanDerWaalsContact O-N 3.09Å; A442-T446 WeakPolarHBondContact O-CG2 3.5Å; A442-T446 PolarHBondContact O-N 2.84Å; A442-T446 PolarHBondContact O-OG1 2.97Å; A442-V457 HydrophobicContact CB-CG1 4.04Å; A442-V457 HydrophobicContact CB-CG2 4.18Å
443	R	72.3	Confident	78.7	Confident	82 Å²	82	55.3 Å²	55.3	31%	0.309	30%	0.296	S	S	.	.	H	α-helix	trans	-67.8	-32.1	178.5	-163.7	158.3	-167.6	136.2	-8.3	113.4	S102 P439 I441 L445	S102-R443 VanDerWaalsContact CB-NE 3.32Å; S102-R443 PolarHBondContact OG-NH2 3.42Å; P439-R443 VanDerWaalsContact O-CB 3.28Å; P439-R443 WeakPolarHBondContact O-CB 3.34Å; P439-R443 PolarHBondContact O-N 2.87Å; I441-R443 VanDerWaalsContact C-N 3.33Å; I441-R443 PolarHBondContact O-N 3.47Å; R443-L445 VanDerWaalsContact C-N 3.28Å
444	A	78.6	Confident	78.4	Confident	76 Å²	76	53.1 Å²	53.1	63%	0.628	28%	0.284	S	S	*	.	H	α-helix	trans	-67.8	-30	172.2	0	0	0	0	0	112.5	V440 I441 A442	V440-A444 WeakPolarHBondContact O-CB 3.42Å; V440-A444 PolarHBondContact O-N 3.36Å; I441-A444 PolarHBondContact O-N 3.38Å; A442-A444 VanDerWaalsContact C-N 3.34Å; A442-A444 PolarHBondContact O-N 3.06Å
445	L	81.3	Confident	78.5	Confident	68 Å²	68	54.9 Å²	54.9	36%	0.356	29%	0.292	S	S	.	.	H	α-helix	trans	-84.7	-24.8	177.8	-67.1	172.7	0	0	0	113.2	I441 A442 R443 E453 V457 I460	I441-L445 HydrophobicContact CG2-CD1 3.72Å; I441-L445 HydrophobicContact CG2-CG 4.34Å; I441-L445 VanDerWaalsContact O-CG 3.27Å; I441-L445 WeakPolarHBondContact O-CG 3.38Å; I441-L445 PolarHBondContact O-N 3.27Å; A442-L445 CarbonylContact O-C 3.56Å; A442-L445 PolarHBondContact O-N 3.37Å; A442-L445 VanDerWaalsContact O-N 3.09Å; R443-L445 VanDerWaalsContact C-N 3.28Å; L445-E453 WeakPolarHBondContact O-CB 3.27Å; L445-E453 VanDerWaalsContact O-CG 3.27Å; L445-E453 WeakPolarHBondContact O-CG 3.37Å; L445-V457 HydrophobicContact CB-CG2 4.21Å; L445-V457 HydrophobicContact CD1-CG2 4.35Å; L445-I460 HydrophobicContact CD1-CD1 3.52Å
446	T	76.1	Confident	79	Confident	11 Å²	11	61 Å²	61	7%	0.067	32%	0.319	C	S	.	.			trans	-107.1	51.5	-176.4	64.7	0	0	0	0	112.3	A442 N448 N449 E453 W454 V457	A442-T446 WeakPolarHBondContact O-CG2 3.5Å; A442-T446 PolarHBondContact O-N 2.84Å; A442-T446 PolarHBondContact O-OG1 2.97Å; T446-N448 VanDerWaalsContact C-N 3.35Å; T446-N448 PolarHBondContact O-N 2.96Å; T446-N449 PolarHBondContact O-N 3.18Å; T446-N449 PolarHBondContact O-OD1 3.46Å; T446-E453 WeakPolarHBondContact CA-OE2 3.26Å; T446-E453 HydrophobicContact CG2-CB 4.14Å; T446-W454 HydrophobicContact CG2-CD2 3.88Å; T446-W454 HydrophobicContact CG2-CE3 4.35Å; T446-W454 HydrophobicContact CG2-CG 4.17Å; T446-W454 HydrophobicContact CG2-CZ2 4.13Å; T446-V457 HydrophobicContact CG2-CG2 3.8Å
447	H	72	Confident	79.3	Confident	157 Å²	157	60 Å²	60	73%	0.727	32%	0.315	S	S	*	.	S	Bend	trans	-67.6	-35.4	-175.5	-163.6	-73.5	0	0	0	112.6	E453	H447-E453 PolarHBondContact N-OE2 2.99Å
448	N	70.1	Confident	79.7	Confident	115 Å²	115	57.5 Å²	57.5	62%	0.615	30%	0.299	S	S	*	.	S	Bend	trans	-101.5	3.2	-179.3	-58	-48.3	0	0	0	112.7	T446 T450 E453	T446-N448 VanDerWaalsContact C-N 3.35Å; T446-N448 PolarHBondContact O-N 2.96Å; N448-T450 VanDerWaalsContact C-N 3.26Å; N448-T450 HydrophobicContact CB-CG2 3.91Å; N448-T450 PolarHBondContact O-N 3.48Å; N448-E453 WeakPolarHBondContact CB-OE1 3.41Å; N448-E453 PolarHBondContact N-OE1 3.01Å; N448-E453 PolarHBondContact N-OE2 3.17Å; N448-E453 PolarHBondContact ND2-OE1 3.43Å
449	N	71.6	Confident	80.4	Confident	61 Å²	61	60.9 Å²	60.9	33%	0.326	31%	0.312	S	S	.	.			trans	50.9	45.7	-177.8	-76.9	-37.1	0	0	0	112.1	I317 T446 E453	I317-N449 HydrophobicContact CD1-CB 3.77Å; I317-N449 WeakPolarHBondContact CD1-O 3.47Å; T446-N449 PolarHBondContact O-N 3.18Å; T446-N449 PolarHBondContact O-OD1 3.46Å; N449-E453 PolarHBondContact N-OE2 3.44Å
450	T	78.8	Confident	81.3	Confident	56 Å²	56	62.9 Å²	62.9	34%	0.344	32%	0.321	S	S	.	.			trans	-94.7	156.6	177.9	65.3	0	0	0	0	112	N448 E452 E453 W454	N448-T450 VanDerWaalsContact C-N 3.26Å; N448-T450 HydrophobicContact CB-CG2 3.91Å; N448-T450 PolarHBondContact O-N 3.48Å; T450-E452 PolarHBondContact O-N 3.19Å; T450-E453 PolarHBondContact N-OE2 3.25Å; T450-E453 PolarHBondContact O-N 3.31Å; T450-E453 VanDerWaalsContact OG1-CG 3.24Å; T450-E453 WeakPolarHBondContact OG1-CG 3.21Å; T450-E453 PolarHBondContact OG1-N 3.28Å; T450-W454 VanDerWaalsContact O-CD1 3.24Å; T450-W454 PolarHBondContact O-N 3.44Å
451	I	78.9	Confident	82	Confident	44 Å²	44	58.6 Å²	58.6	23%	0.226	30%	0.295	C	S	.	.	H	α-helix	trans	-58.4	-39.2	177.5	-63.4	173.7	0	0	0	111.1	W454 Q455	I451-W454 PolarHBondContact O-N 3.31Å; I451-Q455 WeakPolarHBondContact O-CG 3.47Å; I451-Q455 PolarHBondContact O-N 3.45Å
452	E	82.8	Confident	82.6	Confident	139 Å²	139	56 Å²	56	65%	0.65	28%	0.283	S	S	*	.	H	α-helix	trans	-64	-43.2	179.8	-63.1	-178.8	-175.4	0	0	111.9	T450 W454 Q455 F456	T450-E452 PolarHBondContact O-N 3.19Å; E452-W454 VanDerWaalsContact C-N 3.31Å; E452-W454 PolarHBondContact O-N 3.44Å; E452-Q455 WeakPolarHBondContact O-CB 3.44Å; E452-Q455 PolarHBondContact O-N 2.88Å; E452-Q455 VanDerWaalsContact O-N 3.17Å; E452-F456 VanDerWaalsContact O-CD2 3.31Å; E452-F456 WeakPolarHBondContact O-CD2 3.19Å; E452-F456 PolarHBondContact O-N 3.41Å
453	E	84.8	Confident	83.5	Confident	33 Å²	33	59 Å²	59	15%	0.154	31%	0.307	C	S	.	.	H	α-helix	trans	-60.3	-41.3	175	-72.9	170.3	174.5	0	0	111.5	L445 T446 H447 N448 N449 T450 Q455 F456 V457	L445-E453 WeakPolarHBondContact O-CB 3.27Å; L445-E453 VanDerWaalsContact O-CG 3.27Å; L445-E453 WeakPolarHBondContact O-CG 3.37Å; T446-E453 WeakPolarHBondContact CA-OE2 3.26Å; T446-E453 HydrophobicContact CG2-CB 4.14Å; H447-E453 PolarHBondContact N-OE2 2.99Å; N448-E453 WeakPolarHBondContact CB-OE1 3.41Å; N448-E453 PolarHBondContact N-OE1 3.01Å; N448-E453 PolarHBondContact N-OE2 3.17Å; N448-E453 PolarHBondContact ND2-OE1 3.43Å; N449-E453 PolarHBondContact N-OE2 3.44Å; T450-E453 PolarHBondContact N-OE2 3.25Å; T450-E453 PolarHBondContact O-N 3.31Å; T450-E453 VanDerWaalsContact OG1-CG 3.24Å; T450-E453 WeakPolarHBondContact OG1-CG 3.21Å; T450-E453 PolarHBondContact OG1-N 3.28Å; E453-Q455 VanDerWaalsContact C-N 3.35Å; E453-Q455 PolarHBondContact O-N 3.26Å; E453-F456 WeakPolarHBondContact O-CB 3.31Å; E453-F456 PolarHBondContact O-N 3.35Å; E453-V457 PolarHBondContact O-N 3.47Å
454	W	83.5	Confident	84.6	Confident	10 Å²	10	56.7 Å²	56.7	4%	0.038	30%	0.301	C	S	.	.	H	α-helix	trans	-67.2	-31.8	175.7	-79.7	102.4	0	0	0	113.4	L309 Y313 T446 T450 I451 E452 F456 V457 F458	L309-W454 HydrophobicContact CB-CH2 3.88Å; L309-W454 HydrophobicContact CB-CZ3 4.17Å; L309-W454 HydrophobicContact CD1-CH2 4.2Å; L309-W454 HydrophobicContact CD1-CZ3 4.17Å; L309-W454 HydrophobicContact CG-CH2 4.5Å; Y313-W454 AromaticContact CD2-CD2 3.63Å; Y313-W454 HydrophobicContact CD2-CD2 3.63Å; Y313-W454 AromaticContact CD2-CE2 3.73Å; Y313-W454 AromaticContact CD2-CE3 4Å; Y313-W454 HydrophobicContact CD2-CE3 4Å; Y313-W454 AromaticContact CD2-CG 3.96Å; Y313-W454 HydrophobicContact CD2-CG 3.96Å; Y313-W454 HydrophobicContact CD2-CZ2 4.19Å; Y313-W454 HydrophobicContact CD2-CZ3 4.43Å; Y313-W454 HydrophobicContact CE2-CB 4.31Å; Y313-W454 HydrophobicContact CE2-CD2 4.06Å; Y313-W454 AromaticContact CE2-CG 3.92Å; Y313-W454 HydrophobicContact CE2-CG 3.92Å; T446-W454 HydrophobicContact CG2-CD2 3.88Å; T446-W454 HydrophobicContact CG2-CE3 4.35Å; T446-W454 HydrophobicContact CG2-CG 4.17Å; T446-W454 HydrophobicContact CG2-CZ2 4.13Å; T450-W454 VanDerWaalsContact O-CD1 3.24Å; T450-W454 PolarHBondContact O-N 3.44Å; I451-W454 PolarHBondContact O-N 3.31Å; E452-W454 VanDerWaalsContact C-N 3.31Å; E452-W454 PolarHBondContact O-N 3.44Å; W454-F456 VanDerWaalsContact C-N 3.3Å; W454-F456 PolarHBondContact O-N 3.13Å; W454-V457 HydrophobicContact CE3-CB 4.37Å; W454-V457 HydrophobicContact CE3-CG1 4.47Å; W454-V457 HydrophobicContact CZ3-CG1 4.45Å; W454-V457 PolarHBondContact O-N 3.49Å; W454-F458 HydrophobicContact CE3-CE1 4.47Å; W454-F458 HydrophobicContact CE3-CZ 4.44Å; W454-F458 WeakPolarHBondContact O-CD2 3.32Å; W454-F458 WeakPolarHBondContact O-CG 3.4Å; W454-F458 PolarHBondContact O-N 3.3Å
455	Q	88.8	Confident	85.4	Confident	37 Å²	37	53.1 Å²	53.1	17%	0.173	27%	0.271	C	S	.	.	H	α-helix	trans	-60.5	-41.1	172.9	-71.3	169.3	-5.9	0	0	111.4	G381 I451 E452 E453 V457 F458 Y459	G381-Q455 VanDerWaalsContact O-CG 3.32Å; G381-Q455 WeakPolarHBondContact O-CG 3.36Å; G381-Q455 PolarHBondContact O-NE2 3.33Å; I451-Q455 WeakPolarHBondContact O-CG 3.47Å; I451-Q455 PolarHBondContact O-N 3.45Å; E452-Q455 WeakPolarHBondContact O-CB 3.44Å; E452-Q455 PolarHBondContact O-N 2.88Å; E452-Q455 VanDerWaalsContact O-N 3.17Å; E453-Q455 VanDerWaalsContact C-N 3.35Å; E453-Q455 PolarHBondContact O-N 3.26Å; Q455-V457 PolarHBondContact O-N 3.24Å; Q455-F458 PolarHBondContact O-N 3.18Å; Q455-Y459 HydrophobicContact CB-CE2 4.06Å; Q455-Y459 VanDerWaalsContact O-CD2 3.26Å; Q455-Y459 WeakPolarHBondContact O-CD2 3.26Å; Q455-Y459 VanDerWaalsContact O-CG 3.28Å; Q455-Y459 PolarHBondContact O-N 3.44Å
456	F	88.9	Confident	86.1	Confident	128 Å²	128	52.5 Å²	52.5	56%	0.561	27%	0.27	S	S	*	.	H	α-helix	trans	-61.4	-42.2	175.3	-79.6	-77.6	0	0	0	112.5	E452 E453 W454 F458 Y459 I460	E452-F456 VanDerWaalsContact O-CD2 3.31Å; E452-F456 WeakPolarHBondContact O-CD2 3.19Å; E452-F456 PolarHBondContact O-N 3.41Å; E453-F456 WeakPolarHBondContact O-CB 3.31Å; E453-F456 PolarHBondContact O-N 3.35Å; W454-F456 VanDerWaalsContact C-N 3.3Å; W454-F456 PolarHBondContact O-N 3.13Å; F456-F458 VanDerWaalsContact C-N 3.3Å; F456-F458 PolarHBondContact O-N 3.31Å; F456-Y459 HydrophobicContact CD1-CD2 4.33Å; F456-Y459 PolarHBondContact O-N 2.92Å; F456-I460 WeakPolarHBondContact O-CG1 3.43Å; F456-I460 PolarHBondContact O-N 3.41Å; F456-I460 VanDerWaalsContact O-N 3.09Å
457	V	88.4	Confident	87.1	Confident	7 Å²	7	57.9 Å²	57.9	4%	0.042	29%	0.293	C	S	.	.	H	α-helix	trans	-58.6	-43.9	174.9	179	0	0	0	0	110.8	T305 A442 L445 T446 E453 W454 Q455 I460 A461	T305-V457 HydrophobicContact CG2-CG1 4.03Å; A442-V457 HydrophobicContact CB-CG1 4.04Å; A442-V457 HydrophobicContact CB-CG2 4.18Å; L445-V457 HydrophobicContact CB-CG2 4.21Å; L445-V457 HydrophobicContact CD1-CG2 4.35Å; T446-V457 HydrophobicContact CG2-CG2 3.8Å; E453-V457 PolarHBondContact O-N 3.47Å; W454-V457 HydrophobicContact CE3-CB 4.37Å; W454-V457 HydrophobicContact CE3-CG1 4.47Å; W454-V457 HydrophobicContact CZ3-CG1 4.45Å; W454-V457 PolarHBondContact O-N 3.49Å; Q455-V457 PolarHBondContact O-N 3.24Å; V457-I460 PolarHBondContact O-N 2.98Å; V457-A461 PolarHBondContact O-N 3.47Å
458	F	90.1	Very high	88.3	Confident	6 Å²	6	50.4 Å²	50.4	3%	0.026	26%	0.258	C	S	.	.	H	α-helix	trans	-67.8	-35.7	177.5	-64	-28.3	0	0	0	113.4	L377 A380 L394 W454 Q455 F456 A461 A462	L377-F458 HydrophobicContact CD1-CD1 3.61Å; L377-F458 HydrophobicContact CD1-CE1 3.81Å; L377-F458 HydrophobicContact CD1-CG 4.28Å; L377-F458 HydrophobicContact CD2-CB 4.32Å; L377-F458 HydrophobicContact CD2-CD1 4.01Å; L377-F458 HydrophobicContact CD2-CG 4.5Å; L377-F458 HydrophobicContact CG-CB 3.95Å; L377-F458 HydrophobicContact CG-CD1 3.57Å; L377-F458 HydrophobicContact CG-CE1 4.29Å; L377-F458 HydrophobicContact CG-CG 3.87Å; L377-F458 WeakPolarHBondContact O-CD2 3.21Å; A380-F458 HydrophobicContact CB-CE2 4.42Å; L394-F458 HydrophobicContact CD2-CZ 4.36Å; W454-F458 HydrophobicContact CE3-CE1 4.47Å; W454-F458 HydrophobicContact CE3-CZ 4.44Å; W454-F458 WeakPolarHBondContact O-CD2 3.32Å; W454-F458 WeakPolarHBondContact O-CG 3.4Å; W454-F458 PolarHBondContact O-N 3.3Å; Q455-F458 PolarHBondContact O-N 3.18Å; F456-F458 VanDerWaalsContact C-N 3.3Å; F456-F458 PolarHBondContact O-N 3.31Å; F458-A461 PolarHBondContact O-N 3.38Å; F458-A462 VanDerWaalsContact O-CB 3.26Å; F458-A462 WeakPolarHBondContact O-CB 3.23Å; F458-A462 PolarHBondContact O-N 3.42Å
459	Y	92.6	Very high	89.6	Confident	73 Å²	73	45 Å²	45	29%	0.286	23%	0.229	S	C	.	.	H	α-helix	trans	-63.5	-42.6	174.2	-63.9	-37.1	0	0	0	112.7	V378 Y382 Q455 F456 A462 A463	V378-Y459 HydrophobicContact CG1-CD1 4.33Å; V378-Y459 HydrophobicContact CG1-CE1 3.85Å; V378-Y459 HydrophobicContact CG2-CD1 3.99Å; V378-Y459 HydrophobicContact CG2-CE1 4.35Å; Y382-Y459 HydrophobicContact CE2-CE1 4.12Å; Y382-Y459 WeakPolarHBondContact CE2-OH 3.5Å; Y382-Y459 PolarHBondContact OH-OH 2.9Å; Q455-Y459 HydrophobicContact CB-CE2 4.06Å; Q455-Y459 VanDerWaalsContact O-CD2 3.26Å; Q455-Y459 WeakPolarHBondContact O-CD2 3.26Å; Q455-Y459 VanDerWaalsContact O-CG 3.28Å; Q455-Y459 PolarHBondContact O-N 3.44Å; F456-Y459 HydrophobicContact CD1-CD2 4.33Å; F456-Y459 PolarHBondContact O-N 2.92Å; Y459-A462 PolarHBondContact O-N 3.05Å; Y459-A463 WeakPolarHBondContact O-CB 3.44Å; Y459-A463 PolarHBondContact O-N 3.38Å
460	I	92.2	Very high	90.8	Very high	62 Å²	62	46.6 Å²	46.6	32%	0.318	24%	0.237	S	C	.	.	H	α-helix	trans	-61.5	-49.2	178.5	-67.3	167.6	0	0	0	109.7	W301 L445 F456 V457 A462 A463 I464	W301-I460 HydrophobicContact CZ2-CG2 3.99Å; L445-I460 HydrophobicContact CD1-CD1 3.52Å; F456-I460 WeakPolarHBondContact O-CG1 3.43Å; F456-I460 PolarHBondContact O-N 3.41Å; F456-I460 VanDerWaalsContact O-N 3.09Å; V457-I460 PolarHBondContact O-N 2.98Å; I460-A462 VanDerWaalsContact C-N 3.35Å; I460-A462 PolarHBondContact O-N 3.31Å; I460-A463 PolarHBondContact O-N 2.95Å; I460-I464 HydrophobicContact CG2-CD1 3.78Å; I460-I464 WeakPolarHBondContact O-CB 3.44Å; I460-I464 VanDerWaalsContact O-CG1 3.29Å; I460-I464 WeakPolarHBondContact O-CG1 2.91Å; I460-I464 PolarHBondContact O-N 3.29Å
461	A	91.9	Very high	91.7	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-61.1	-41.7	177.3	0	0	0	0	0	112.5	L377 V457 F458 N465	L377-A461 HydrophobicContact CD2-CB 3.42Å; L377-A461 VanDerWaalsContact CD2-CB 3.42Å; V457-A461 PolarHBondContact O-N 3.47Å; F458-A461 PolarHBondContact O-N 3.38Å; A461-N465 WeakPolarHBondContact O-CB 3.33Å; A461-N465 PolarHBondContact O-N 3.05Å
462	A	93.9	Very high	92.5	Very high	9 Å²	9	44.2 Å²	44.2	7%	0.074	22%	0.221	C	C	.	.	H	α-helix	trans	-64.3	-45.2	177.4	0	0	0	0	0	112.6	A374 V378 F458 Y459 I460 I464 N465 V466	A374-A462 HydrophobicContact CB-CB 3.88Å; V378-A462 HydrophobicContact CG2-CB 3.55Å; F458-A462 VanDerWaalsContact O-CB 3.26Å; F458-A462 WeakPolarHBondContact O-CB 3.23Å; F458-A462 PolarHBondContact O-N 3.42Å; Y459-A462 PolarHBondContact O-N 3.05Å; I460-A462 VanDerWaalsContact C-N 3.35Å; I460-A462 PolarHBondContact O-N 3.31Å; A462-I464 PolarHBondContact O-N 3.14Å; A462-N465 PolarHBondContact O-N 3.24Å; A462-V466 WeakPolarHBondContact O-CG2 3.44Å; A462-V466 PolarHBondContact O-N 3.26Å
463	A	95.7	Very high	93.1	Very high	64 Å²	64	38.7 Å²	38.7	53%	0.529	20%	0.199	S	C	.	.	H	α-helix	trans	-61.5	-44.4	178.1	0	0	0	0	0	111.7	Y459 I460 N465 V466 F467	Y459-A463 WeakPolarHBondContact O-CB 3.44Å; Y459-A463 PolarHBondContact O-N 3.38Å; I460-A463 PolarHBondContact O-N 2.95Å; A463-N465 PolarHBondContact O-N 3.16Å; A463-V466 PolarHBondContact O-N 3.07Å; A463-F467 WeakPolarHBondContact O-CB 3.5Å; A463-F467 PolarHBondContact O-N 3.35Å
464	I	95.7	Very high	93.6	Very high	35 Å²	35	41.5 Å²	41.5	18%	0.179	22%	0.218	C	C	.	.	H	α-helix	trans	-62.5	-42.4	177.4	-70.6	170.2	0	0	0	111.2	F297 S298 W301 I460 A462 G468	F297-I464 HydrophobicContact CD1-CG2 4.44Å; F297-I464 HydrophobicContact CE1-CG2 4.28Å; S298-I464 VanDerWaalsContact CB-O 3.26Å; S298-I464 WeakPolarHBondContact CB-O 3.46Å; S298-I464 PolarHBondContact OG-O 3.46Å; W301-I464 HydrophobicContact CB-CG2 4.05Å; W301-I464 HydrophobicContact CD2-CD1 3.53Å; W301-I464 HydrophobicContact CE3-CD1 3.94Å; W301-I464 HydrophobicContact CG-CD1 3.88Å; W301-I464 HydrophobicContact CG-CG2 4.21Å; W301-I464 HydrophobicContact CH2-CD1 4.33Å; W301-I464 HydrophobicContact CZ2-CD1 3.95Å; W301-I464 HydrophobicContact CZ3-CD1 4.34Å; I460-I464 HydrophobicContact CG2-CD1 3.78Å; I460-I464 WeakPolarHBondContact O-CB 3.44Å; I460-I464 VanDerWaalsContact O-CG1 3.29Å; I460-I464 WeakPolarHBondContact O-CG1 2.91Å; I460-I464 PolarHBondContact O-N 3.29Å; A462-I464 PolarHBondContact O-N 3.14Å; I464-G468 PolarHBondContact O-N 3.3Å
465	N	94.7	Very high	94.2	Very high	1 Å²	1	44.6 Å²	44.6	1%	0.005	23%	0.232	C	C	.	.	H	α-helix	trans	-63.1	-48.2	175.9	-94.1	-17.4	0	0	0	112.6	S298 T302 A374 A461 A462 A463 F467 G468 A469	S298-N465 PolarHBondContact O-OD1 3.09Å; T302-N465 VanDerWaalsContact OG1-CG 3.29Å; T302-N465 PolarHBondContact OG1-ND2 2.97Å; T302-N465 PolarHBondContact OG1-OD1 3.08Å; A374-N465 HydrophobicContact CB-CB 4.01Å; A461-N465 WeakPolarHBondContact O-CB 3.33Å; A461-N465 PolarHBondContact O-N 3.05Å; A462-N465 PolarHBondContact O-N 3.24Å; A463-N465 PolarHBondContact O-N 3.16Å; N465-F467 VanDerWaalsContact C-N 3.34Å; N465-F467 PolarHBondContact O-N 3.46Å; N465-G468 PolarHBondContact O-N 3.32Å; N465-A469 WeakPolarHBondContact O-CB 3.24Å; N465-A469 PolarHBondContact O-N 2.84Å
466	V	97.1	Very high	94.3	Very high	54 Å²	54	42.9 Å²	42.9	33%	0.327	22%	0.224	S	C	.	.	H	α-helix	trans	-61.6	-45.2	179.8	171.3	0	0	0	0	110.3	A374 A462 A463 G468 A469 L470	A374-V466 HydrophobicContact CB-CG2 4Å; A462-V466 WeakPolarHBondContact O-CG2 3.44Å; A462-V466 PolarHBondContact O-N 3.26Å; A463-V466 PolarHBondContact O-N 3.07Å; V466-G468 PolarHBondContact O-N 3.28Å; V466-A469 PolarHBondContact O-N 3.23Å; V466-L470 HydrophobicContact CG1-CD1 3.94Å; V466-L470 HydrophobicContact CG1-CG 4.38Å; V466-L470 VanDerWaalsContact O-CG 3.29Å; V466-L470 WeakPolarHBondContact O-CG 3.41Å; V466-L470 PolarHBondContact O-N 3.13Å
467	F	97.4	Very high	94.5	Very high	125 Å²	125	43.5 Å²	43.5	55%	0.548	22%	0.223	S	C	.	.	H	α-helix	trans	-57.6	-48.9	175.3	175.1	-101	0	0	0	111.9	V294 A463 N465 A469 L470 F471	V294-F467 HydrophobicContact CG1-CD1 4.14Å; V294-F467 HydrophobicContact CG1-CE1 3.78Å; A463-F467 WeakPolarHBondContact O-CB 3.5Å; A463-F467 PolarHBondContact O-N 3.35Å; N465-F467 VanDerWaalsContact C-N 3.34Å; N465-F467 PolarHBondContact O-N 3.46Å; F467-A469 VanDerWaalsContact C-N 3.33Å; F467-A469 PolarHBondContact O-N 3.27Å; F467-L470 PolarHBondContact O-N 2.95Å; F467-F471 HydrophobicContact CZ-CD2 4.28Å; F467-F471 WeakPolarHBondContact O-CB 3.47Å; F467-F471 PolarHBondContact O-N 3.4Å
468	G	96.8	Very high	94.2	Very high	0 Å²	0	43.6 Å²	43.6	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-62.9	-39.5	179.9	0	0	0	0	0	113.2	S298 I464 N465 V466 Y472	S298-G468 WeakPolarHBondContact OG-CA 3.42Å; I464-G468 PolarHBondContact O-N 3.3Å; N465-G468 PolarHBondContact O-N 3.32Å; V466-G468 PolarHBondContact O-N 3.28Å; G468-Y472 WeakPolarHBondContact O-CB 3.4Å; G468-Y472 PolarHBondContact O-N 3.39Å
469	A	96.4	Very high	93.9	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-62.8	-46.7	177.1	0	0	0	0	0	111.7	L367 M370 I371 N465 V466 F467 A473	L367-A469 HydrophobicContact CD2-CB 4.14Å; M370-A469 HydrophobicContact CB-CB 3.7Å; M370-A469 HydrophobicContact SD-CB 4.21Å; I371-A469 HydrophobicContact CD1-CB 4.31Å; I371-A469 HydrophobicContact CG1-CB 3.83Å; N465-A469 WeakPolarHBondContact O-CB 3.24Å; N465-A469 PolarHBondContact O-N 2.84Å; V466-A469 PolarHBondContact O-N 3.23Å; F467-A469 VanDerWaalsContact C-N 3.33Å; F467-A469 PolarHBondContact O-N 3.27Å; A469-A473 VanDerWaalsContact O-CB 3.28Å; A469-A473 WeakPolarHBondContact O-CB 3.32Å; A469-A473 PolarHBondContact O-N 2.6Å
470	L	97.3	Very high	93.5	Very high	95 Å²	95	47.3 Å²	47.3	50%	0.497	26%	0.255	S	S	.	.	H	α-helix	trans	-66.7	-45.1	179.1	-67.7	176.3	0	0	0	111.5	V466 F467 Y472 A473 V474	V466-L470 HydrophobicContact CG1-CD1 3.94Å; V466-L470 HydrophobicContact CG1-CG 4.38Å; V466-L470 VanDerWaalsContact O-CG 3.29Å; V466-L470 WeakPolarHBondContact O-CG 3.41Å; V466-L470 PolarHBondContact O-N 3.13Å; F467-L470 PolarHBondContact O-N 2.95Å; L470-Y472 VanDerWaalsContact C-N 3.33Å; L470-Y472 PolarHBondContact O-N 3.05Å; L470-A473 PolarHBondContact O-N 3.28Å; L470-V474 WeakPolarHBondContact O-CG2 3.05Å; L470-V474 PolarHBondContact O-N 2.77Å
471	F	97.3	Very high	93.2	Very high	49 Å²	49	45.5 Å²	45.5	22%	0.215	25%	0.246	C	C	.	.	H	α-helix	trans	-59.6	-45.3	178.2	-167.8	-91	0	0	0	111.2	M287 A291 V294 F467 V474 F475	M287-F471 HydrophobicContact SD-CZ 4.37Å; A291-F471 HydrophobicContact CB-CD1 4.45Å; A291-F471 HydrophobicContact CB-CE1 4.38Å; V294-F471 HydrophobicContact CB-CD1 3.76Å; V294-F471 HydrophobicContact CB-CE1 4.2Å; V294-F471 HydrophobicContact CB-CG 4.4Å; V294-F471 HydrophobicContact CG1-CB 4.01Å; V294-F471 HydrophobicContact CG1-CD1 3.89Å; V294-F471 HydrophobicContact CG1-CG 4.03Å; V294-F471 HydrophobicContact CG2-CD1 3.91Å; V294-F471 HydrophobicContact CG2-CE1 3.88Å; F467-F471 HydrophobicContact CZ-CD2 4.28Å; F467-F471 WeakPolarHBondContact O-CB 3.47Å; F467-F471 PolarHBondContact O-N 3.4Å; F471-V474 PolarHBondContact O-N 3.05Å; F471-F475 HydrophobicContact CD1-CD2 4.02Å; F471-F475 AromaticContact CD2-CD2 3.79Å; F471-F475 HydrophobicContact CD2-CD2 3.79Å; F471-F475 AromaticContact CD2-CE2 3.81Å; F471-F475 HydrophobicContact CD2-CE2 3.81Å; F471-F475 AromaticContact CE1-CD2 3.85Å; F471-F475 HydrophobicContact CE1-CD2 3.85Å; F471-F475 HydrophobicContact CE1-CG 4.49Å; F471-F475 AromaticContact CE2-CD2 3.61Å; F471-F475 HydrophobicContact CE2-CD2 3.61Å; F471-F475 AromaticContact CE2-CE2 3.53Å; F471-F475 HydrophobicContact CE2-CE2 3.53Å; F471-F475 AromaticContact CG-CD2 3.99Å; F471-F475 HydrophobicContact CG-CD2 3.99Å; F471-F475 HydrophobicContact CG-CE2 4.45Å; F471-F475 AromaticContact CZ-CD2 3.63Å; F471-F475 HydrophobicContact CZ-CD2 3.63Å; F471-F475 AromaticContact CZ-CE2 3.96Å; F471-F475 HydrophobicContact CZ-CE2 3.96Å; F471-F475 HydrophobicContact CZ-CG 4.43Å; F471-F475 WeakPolarHBondContact O-CD2 3.39Å; F471-F475 PolarHBondContact O-N 3.12Å
472	Y	96.6	Very high	92.8	Very high	2 Å²	2	50.7 Å²	50.7	1%	0.008	28%	0.279	C	S	.	.	H	α-helix	trans	-66.5	-38.7	176	-173.5	-99.4	0	0	0	113.1	A291 I292 A295 K363 S366 F408 N411 G468 L470 V474 G476	A291-Y472 HydrophobicContact CB-CD2 4.05Å; I292-Y472 HydrophobicContact CG1-CE2 3.95Å; A295-Y472 HydrophobicContact CB-CD2 3.94Å; A295-Y472 HydrophobicContact CB-CG 4.12Å; K363-Y472 HydrophobicContact CG-CE1 4.47Å; S366-Y472 WeakPolarHBondContact OG-CE1 3.38Å; F408-Y472 WeakPolarHBondContact CA-OH 3.46Å; F408-Y472 HydrophobicContact CB-CD2 4.18Å; F408-Y472 HydrophobicContact CB-CE1 4.14Å; F408-Y472 HydrophobicContact CB-CE2 3.69Å; N411-Y472 WeakPolarHBondContact CB-OH 3.45Å; N411-Y472 PolarHBondContact ND2-OH 3.26Å; G468-Y472 WeakPolarHBondContact O-CB 3.4Å; G468-Y472 PolarHBondContact O-N 3.39Å; L470-Y472 VanDerWaalsContact C-N 3.33Å; L470-Y472 PolarHBondContact O-N 3.05Å; Y472-V474 VanDerWaalsContact C-N 3.25Å; Y472-V474 PolarHBondContact O-N 3.32Å; Y472-G476 VanDerWaalsContact O-CA 3.26Å; Y472-G476 WeakPolarHBondContact O-CA 3.02Å; Y472-G476 PolarHBondContact O-N 3Å
473	A	95.1	Very high	92.3	Very high	23 Å²	23	52.4 Å²	52.4	19%	0.19	28%	0.284	C	S	.	.	H	α-helix	trans	-62.6	-32.9	176.7	0	0	0	0	0	112.4	K363 L367 A469 L470	K363-A473 VanDerWaalsContact CD-O 3.29Å; K363-A473 WeakPolarHBondContact CD-O 3.34Å; K363-A473 WeakPolarHBondContact CE-O 3.15Å; K363-A473 PolarHBondContact NZ-O 3.28Å; L367-A473 HydrophobicContact CD1-CB 4.08Å; L367-A473 HydrophobicContact CD2-CB 3.83Å; L367-A473 HydrophobicContact CG-CB 4.06Å; A469-A473 VanDerWaalsContact O-CB 3.28Å; A469-A473 WeakPolarHBondContact O-CB 3.32Å; A469-A473 PolarHBondContact O-N 2.6Å; L470-A473 PolarHBondContact O-N 3.28Å
474	V	96.1	Very high	91.5	Very high	92 Å²	92	50.1 Å²	50.1	56%	0.558	27%	0.265	S	S	*	.	H	α-helix	trans	-77.5	-55.8	175.5	177.3	0	0	0	0	110.7	K363 L470 F471 Y472	K363-V474 PolarHBondContact NZ-O 3.23Å; L470-V474 WeakPolarHBondContact O-CG2 3.05Å; L470-V474 PolarHBondContact O-N 2.77Å; F471-V474 PolarHBondContact O-N 3.05Å; Y472-V474 VanDerWaalsContact C-N 3.25Å; Y472-V474 PolarHBondContact O-N 3.32Å
475	F	95.3	Very high	90.4	Very high	75 Å²	75	52.7 Å²	52.7	33%	0.329	28%	0.282	S	S	.	.	H	α-helix	trans	-97	-15.1	-164.6	-64.3	-65.2	0	0	0	115.4	M287 A291 F471 R477	M287-F475 HydrophobicContact CG-CB 3.9Å; M287-F475 HydrophobicContact CG-CD1 3.56Å; M287-F475 HydrophobicContact CG-CE1 4.37Å; M287-F475 HydrophobicContact CG-CG 3.91Å; M287-F475 HydrophobicContact SD-CB 4.29Å; M287-F475 HydrophobicContact SD-CD1 3.82Å; M287-F475 HydrophobicContact SD-CD2 4.48Å; M287-F475 HydrophobicContact SD-CE1 4.27Å; M287-F475 HydrophobicContact SD-CG 3.93Å; A291-F475 HydrophobicContact CB-CB 3.8Å; F471-F475 HydrophobicContact CD1-CD2 4.02Å; F471-F475 AromaticContact CD2-CD2 3.79Å; F471-F475 HydrophobicContact CD2-CD2 3.79Å; F471-F475 AromaticContact CD2-CE2 3.81Å; F471-F475 HydrophobicContact CD2-CE2 3.81Å; F471-F475 AromaticContact CE1-CD2 3.85Å; F471-F475 HydrophobicContact CE1-CD2 3.85Å; F471-F475 HydrophobicContact CE1-CG 4.49Å; F471-F475 AromaticContact CE2-CD2 3.61Å; F471-F475 HydrophobicContact CE2-CD2 3.61Å; F471-F475 AromaticContact CE2-CE2 3.53Å; F471-F475 HydrophobicContact CE2-CE2 3.53Å; F471-F475 AromaticContact CG-CD2 3.99Å; F471-F475 HydrophobicContact CG-CD2 3.99Å; F471-F475 HydrophobicContact CG-CE2 4.45Å; F471-F475 AromaticContact CZ-CD2 3.63Å; F471-F475 HydrophobicContact CZ-CD2 3.63Å; F471-F475 AromaticContact CZ-CE2 3.96Å; F471-F475 HydrophobicContact CZ-CE2 3.96Å; F471-F475 HydrophobicContact CZ-CG 4.43Å; F471-F475 WeakPolarHBondContact O-CD2 3.39Å; F471-F475 PolarHBondContact O-N 3.12Å; F475-R477 PolarHBondContact O-N 3.32Å
476	G	92.1	Very high	88.7	Confident	1 Å²	1	59.8 Å²	59.8	1%	0.01	31%	0.309	C	S	.	.			trans	-59.6	135.1	179.1	0	0	0	0	0	112.1	K363 Y472	K363-G476 WeakPolarHBondContact CE-O 3.38Å; K363-G476 PolarHBondContact NZ-O 2.74Å; Y472-G476 VanDerWaalsContact O-CA 3.26Å; Y472-G476 WeakPolarHBondContact O-CA 3.02Å; Y472-G476 PolarHBondContact O-N 3Å
477	R	91.3	Very high	86.3	Confident	141 Å²	141	62.4 Å²	62.4	53%	0.532	33%	0.325	S	S	.	.			trans	-125.3	158.9	172.3	-59	-65.5	-179.2	160.6	-0.5	108.4	P288 N411 F475	P288-R477 HydrophobicContact CB-CB 4.05Å; P288-R477 HydrophobicContact CB-CG 4.18Å; P288-R477 HydrophobicContact CG-CB 3.96Å; P288-R477 HydrophobicContact CG-CG 3.63Å; N411-R477 VanDerWaalsContact CG-O 3.28Å; N411-R477 PolarHBondContact ND2-O 2.92Å; N411-R477 PolarHBondContact OD1-O 3.25Å; F475-R477 PolarHBondContact O-N 3.32Å
478	G	82.9	Confident	83.7	Confident	8 Å²	8	62.3 Å²	62.3	8%	0.082	34%	0.335	C	S	.	.			trans	-137	32.8	-178.9	0	0	0	0	0	111.3
479	T	83.4	Confident	80.9	Confident	86 Å²	86	71.2 Å²	71.2	53%	0.528	37%	0.37	S	S	.	.	S	Bend	trans	-124.8	148.7	175.9	56.2	0	0	0	0	108.4	D414 Q481	D414-T479 CarbonylContact O-C 3.55Å; T479-Q481 PolarHBondContact O-N 2.83Å; T479-Q481 PolarHBondContact O-NE2 3.17Å
480	V	84.2	Confident	77.9	Confident	71 Å²	71	76.5 Å²	76.5	43%	0.43	41%	0.407	S	S	.	.			trans	-58.3	134.4	179.5	-173.7	0	0	0	0	109.9	D414 I415 A484 V485	D414-V480 PolarHBondContact O-N 3.05Å; I415-V480 WeakPolarHBondContact O-CA 3.02Å; V480-A484 HydrophobicContact CG1-CB 4.09Å; V480-V485 HydrophobicContact CB-CG2 4.46Å; V480-V485 HydrophobicContact CG1-CG2 3.58Å
481	Q	86.3	Confident	75	Confident	25 Å²	25	80.1 Å²	80.1	12%	0.117	42%	0.421	C	S	.	.			trans	-82.5	148.5	-176.8	-63.1	-60	-65.1	0	0	111.9	I415 T479 W483 A484	I415-Q481 HydrophobicContact CB-CG 3.99Å; I415-Q481 PolarHBondContact O-N 3.12Å; T479-Q481 PolarHBondContact O-N 2.83Å; T479-Q481 PolarHBondContact O-NE2 3.17Å; Q481-W483 VanDerWaalsContact C-N 3.28Å; Q481-W483 HydrophobicContact CB-CD2 4.08Å; Q481-W483 VanDerWaalsContact CB-CE2 3.48Å; Q481-W483 HydrophobicContact CB-CG 4.34Å; Q481-W483 HydrophobicContact CB-CZ2 3.81Å; Q481-W483 HydrophobicContact CG-CZ2 3.93Å; Q481-W483 PolarHBondContact O-N 3.06Å; Q481-A484 WeakPolarHBondContact O-CA 3.33Å; Q481-A484 WeakPolarHBondContact O-CB 3.43Å; Q481-A484 PolarHBondContact O-N 2.03Å
482	P	83.2	Confident	72.1	Confident	108 Å²	108	81.2 Å²	81.2	70%	0.701	45%	0.446	S	S	*	.	G	3₁₀ helix	trans	-58.1	-36.9	-176.1	-25.9	34.3	0	0	0	113.9	A484 V485	P482-A484 PolarHBondContact O-N 3.31Å; P482-V485 PolarHBondContact O-N 3.29Å
483	W	83.7	Confident	69.1	Low	45 Å²	45	92 Å²	92	17%	0.17	50%	0.504	C	S	.	.	G	3₁₀ helix	trans	-71.3	-12.8	178	54.1	-103.6	0	0	0	113.6	A282 I283 A416 Y419 L423 Q481	A282-W483 HydrophobicContact CB-CB 3.91Å; A282-W483 HydrophobicContact CB-CG 4.17Å; I283-W483 HydrophobicContact CD1-CZ3 4.27Å; I283-W483 HydrophobicContact CG1-CD2 4.25Å; I283-W483 HydrophobicContact CG1-CE3 3.73Å; I283-W483 HydrophobicContact CG1-CH2 4.09Å; I283-W483 HydrophobicContact CG1-CZ3 3.65Å; A416-W483 HydrophobicContact CB-CH2 3.4Å; A416-W483 HydrophobicContact CB-CZ2 4.43Å; A416-W483 HydrophobicContact CB-CZ3 3.51Å; Y419-W483 HydrophobicContact CD2-CE3 4.32Å; Y419-W483 AromaticContact CD2-CZ3 3.88Å; Y419-W483 HydrophobicContact CD2-CZ3 3.88Å; L423-W483 HydrophobicContact CD1-CH2 3.97Å; L423-W483 HydrophobicContact CD1-CZ3 4.32Å; L423-W483 HydrophobicContact CD2-CH2 4.15Å; L423-W483 HydrophobicContact CG-CH2 4.48Å; Q481-W483 VanDerWaalsContact C-N 3.28Å; Q481-W483 HydrophobicContact CB-CD2 4.08Å; Q481-W483 VanDerWaalsContact CB-CE2 3.48Å; Q481-W483 HydrophobicContact CB-CG 4.34Å; Q481-W483 HydrophobicContact CB-CZ2 3.81Å; Q481-W483 HydrophobicContact CG-CZ2 3.93Å; Q481-W483 PolarHBondContact O-N 3.06Å
484	A	78.4	Confident	67.8	Low	16 Å²	16	95.5 Å²	95.5	13%	0.132	52%	0.52	C	S	.	.	G	3₁₀ helix	trans	-90.4	-14.3	175.6	0	0	0	0	0	112.6	A416 Y419 V480 Q481 P482	A416-A484 HydrophobicContact CB-CB 3.63Å; Y419-A484 HydrophobicContact CD2-CB 4.47Å; V480-A484 HydrophobicContact CG1-CB 4.09Å; Q481-A484 WeakPolarHBondContact O-CA 3.33Å; Q481-A484 WeakPolarHBondContact O-CB 3.43Å; Q481-A484 PolarHBondContact O-N 2.03Å; P482-A484 PolarHBondContact O-N 3.31Å
485	V	72.6	Confident	66.3	Low	89 Å²	89	95.7 Å²	95.7	54%	0.539	52%	0.518	S	S	.	.	S	Bend	trans	-102.1	141.4	-178.8	-172.2	0	0	0	0	109.8	V480 P482 T487	V480-V485 HydrophobicContact CB-CG2 4.46Å; V480-V485 HydrophobicContact CG1-CG2 3.58Å; P482-V485 PolarHBondContact O-N 3.29Å; V485-T487 PolarHBondContact O-N 3.19Å
486	R	60.1	Low	64.7	Low	151 Å²	151	96.8 Å²	96.8	57%	0.57	53%	0.528	S	S	*	.			trans	-77.8	114.5	173.1	-149.7	-179.2	-165.8	-172	5.9	108.7	T488	R486-T488 PolarHBondContact O-N 2.75Å; R486-T488 VanDerWaalsContact O-N 3.14Å
487	T	46.8	Very low	63.1	Low	109 Å²	109	102.5 Å²	102.5	67%	0.669	56%	0.559	S	S	*	*			trans	-72.8	98.2	160.9	29.2	0	0	0	0	107.7	V485 Y489	V485-T487 PolarHBondContact O-N 3.19Å; T487-Y489 PolarHBondContact O-N 3.37Å
488	T	41.4	Very low	61.3	Low	123 Å²	123	100.1 Å²	100.1	76%	0.755	56%	0.56	S	S	*	*			trans	-66.6	93.6	158.1	33.4	0	0	0	0	106.9	R486 S490	R486-T488 PolarHBondContact O-N 2.75Å; R486-T488 VanDerWaalsContact O-N 3.14Å; T488-S490 PolarHBondContact O-N 3.05Å; T488-S490 VanDerWaalsContact O-N 3.11Å
489	Y	38	Very low	59.9	Low	187 Å²	187	106.2 Å²	106.2	73%	0.733	59%	0.592	S	S	*	*			trans	-63.7	108.5	154	-77.8	-80.9	0	0	0	105.5	T487 H491	T487-Y489 PolarHBondContact O-N 3.37Å; Y489-H491 VanDerWaalsContact C-N 3.29Å; Y489-H491 PolarHBondContact O-N 2.7Å
490	S	34.3	Very low	58.2	Low	111 Å²	111	107.6 Å²	107.6	78%	0.776	60%	0.597	S	S	*	*			trans	-59.4	102.4	160.6	50.6	0	0	0	0	105.8	T488 G492	T488-S490 PolarHBondContact O-N 3.05Å; T488-S490 VanDerWaalsContact O-N 3.11Å; S490-G492 PolarHBondContact O-N 3.44Å
491	H	36.5	Very low	56.2	Low	170 Å²	170	110.5 Å²	110.5	79%	0.787	61%	0.61	S	S	*	*			trans	-61.6	98.2	155.7	-81.2	-73.4	0	0	0	105.1	Y489 D493	Y489-H491 VanDerWaalsContact C-N 3.29Å; Y489-H491 PolarHBondContact O-N 2.7Å; H491-D493 PolarHBondContact O-N 3.13Å
492	G	35.5	Very low	53.7	Low	73 Å²	73	117.6 Å²	117.6	75%	0.753	65%	0.651	S	S	*	*			trans	-69.8	106.6	162.4	0	0	0	0	0	106.2	S490	S490-G492 PolarHBondContact O-N 3.44Å
493	D	34.3	Very low	51.1	Low	229 Å²	229	118.5 Å²	118.5	100%	1.225	65%	0.646	S	S	*	*			trans	-84.2	0	157.5	-73.4	-25.7	0	0	0	109.1	H491	H491-D493 PolarHBondContact O-N 3.13Å

Retrieved 493 of 493 residues in 151.2 ms (Link to these results)

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