A0A087XH24_POEFO Loading...

Calpain 10

AlphaFold DB , UniProt , Accession A0A087XH24, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 666 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1L42.1Very low36.3Very low223 Ų223146.5 Ų146.5100%1.16885%0.849SS**  0113.50-78.8161.4000108.4
2P31.4Very low38.3Very low131 Ų131142.6 Ų142.685%0.85183%0.832SS**  trans-120.8143.2134.719.7-2.3000110.1
3V30.9Very low41.7Very low130 Ų130139.9 Ų139.979%0.78883%0.826SS**  trans-70.7125.6-168.8173.10000110.3M5V3-M5 PolarHBondContact O-N 3.03Å
4A32.8Very low45.4Very low92 Ų92134.4 Ų134.476%0.7679%0.79SS**  trans-66.7113.9164.600000108.7K6A4-K6 PolarHBondContact O-N 2.89Å
5M31Very low48.7Very low179 Ų179130.2 Ų130.288%0.88276%0.758SS**  trans-72.3115.4161.6-67.9-145.7-6300107.4V3 E7V3-M5 PolarHBondContact O-N 3.03Å; M5-E7 PolarHBondContact O-N 3.2Å
6K32.6Very low51.7Low196 Ų196129 Ų12985%0.85274%0.743SS**  trans-57.4117.3168.1-81175.1170.1178.90108.1A4 E8A4-K6 PolarHBondContact O-N 2.89Å; K6-E8 PolarHBondContact O-N 2.89Å; K6-E8 VanDerWaalsContact O-N 3.1Å
7E33.8Very low54.3Low189 Ų189121.6 Ų121.688%0.88370%0.701SS**  trans-61.2104.7154.8-77178.1146.400107.3M5 C9M5-E7 PolarHBondContact O-N 3.2Å; E7-C9 PolarHBondContact O-N 3.24Å
8E36.3Very low56.5Low184 Ų184123.2 Ų123.286%0.8671%0.706SS**  trans-70.3113.4158-82.3-176.8159.400107.5K6 A10K6-E8 PolarHBondContact O-N 2.89Å; K6-E8 VanDerWaalsContact O-N 3.1Å; E8-A10 VanDerWaalsContact C-N 3.34Å; E8-A10 PolarHBondContact O-N 3.44Å
9C37.9Very low58.5Low135 Ų135123.9 Ų123.991%0.91271%0.707SS**  trans-56.390170.7-78.10000111.1E7 G11E7-C9 PolarHBondContact O-N 3.24Å; C9-G11 PolarHBondContact O-N 3.12Å
10A41Very low60.4Low96 Ų96118 Ų11879%0.79367%0.673SS**  trans-77.3110.8160.600000108.2E8E8-A10 VanDerWaalsContact C-N 3.34Å; E8-A10 PolarHBondContact O-N 3.44Å
11G48.9Very low62.1Low57 Ų57114.4 Ų114.459%0.58865%0.654SS**PPolyproline II helixtrans-57.3163.516400000110.8C9 S13C9-G11 PolarHBondContact O-N 3.12Å; G11-S13 PolarHBondContact O-N 3.48Å
12P60.3Low64.6Low99 Ų99107.2 Ų107.264%0.64362%0.616SS**PPolyproline II helixtrans-60.4117.7179.124.5-31.9000109.9
13S82.8Confident67.4Low108 Ų108104.2 Ų104.276%0.75560%0.595SS**PPolyproline II helixtrans-57.5140.6177.353.10000110.9G11G11-S13 PolarHBondContact O-N 3.48Å
14L93.7Very high70.3Confident63 Ų63101.9 Ų101.933%0.3358%0.579SS.*PPolyproline II helixtrans-67.4150.8174.4-63.9178.4000110.3Y106L14-Y106 HydrophobicContact CD1-CE1 4.22Å; L14-Y106 HydrophobicContact CD2-CD1 4Å; L14-Y106 HydrophobicContact CD2-CE1 3.51Å
15F95.3Very high73.1Confident71 Ų71101 Ų10131%0.31157%0.566SS.*PPolyproline II helixtrans-61.1138178.8178.7-111000111D17 R46 R107 T124 D126F15-D17 HydrophobicContact CE1-CB 4.05Å; F15-D17 HydrophobicContact CZ-CB 4.4Å; F15-R46 PolarHBondContact O-NH1 3.1Å; F15-R46 PolarHBondContact O-NH2 3.13Å; F15-R107 WeakPolarHBondContact CB-O 3.23Å; F15-R107 PolarHBondContact N-O 2.91Å; F15-T124 HydrophobicContact CE1-CG2 3.93Å; F15-T124 HydrophobicContact CZ-CG2 4.08Å; F15-D126 HydrophobicContact CD1-CB 3.64Å; F15-D126 HydrophobicContact CE1-CB 4.14Å; F15-D126 WeakPolarHBondContact O-CB 3.33Å
16E96.1Very high76.2Confident111 Ų11192.6 Ų92.652%0.51953%0.525SS..  trans-125.7124174.5-61.6-167.4-178.100108.5L18 R128E16-L18 PolarHBondContact O-N 3.33Å; E16-R128 IonicContact OE1-NH1 2.74Å; E16-R128 IonicContact OE2-NH1 3.78Å
17D96.2Very high79.1Confident4 Ų483.3 Ų83.32%0.02149%0.485CS..  trans-82.9103.6-178.8-166.8-10.5000110.8F15 D19 F20 V125 D126 K158F15-D17 HydrophobicContact CE1-CB 4.05Å; F15-D17 HydrophobicContact CZ-CB 4.4Å; D17-D19 VanDerWaalsContact C-N 3.32Å; D17-D19 PolarHBondContact OD1-N 2.82Å; D17-D19 VanDerWaalsContact OD1-N 3.16Å; D17-F20 CarbonylContact O-C 3.56Å; D17-F20 PolarHBondContact OD1-N 2.84Å; D17-V125 WeakPolarHBondContact OD2-CA 3.3Å; D17-D126 HydrophobicContact CB-CB 4.29Å; D17-D126 VanDerWaalsContact CB-OD2 3.26Å; D17-D126 WeakPolarHBondContact CB-OD2 3.3Å; D17-D126 PolarHBondContact N-OD2 3.49Å; D17-K158 IonicContact OD1-NZ 3.05Å; D17-K158 PolarHBondContact OD1-NZ 2.86Å; D17-K158 WeakPolarHBondContact OD2-CD 3.39Å; D17-K158 IonicContact OD2-NZ 2.77Å; D17-K158 PolarHBondContact OD2-NZ 3.18Å
18L94.5Very high81.9Confident150 Ų15074.8 Ų74.879%0.78545%0.445SS*.SBendtrans-73.9-24.3179-60.3179.7000112.7E16 F20E16-L18 PolarHBondContact O-N 3.33Å; L18-F20 VanDerWaalsContact C-N 3.32Å
19D94.1Very high84.2Confident137 Ų13768.4 Ų68.473%0.73342%0.421SS*.SBendtrans-82.7-15.2178.9-61.9-36.2000112.1D17D17-D19 VanDerWaalsContact C-N 3.32Å; D17-D19 PolarHBondContact OD1-N 2.82Å; D17-D19 VanDerWaalsContact OD1-N 3.16Å
20F97.1Very high86.4Confident4 Ų465.4 Ų65.42%0.01840%0.396CS..SBendtrans-139.971.6176.1-159.3-107.2000110.2D17 L18 S26 W44 K154 A157 K158 Y163D17-F20 CarbonylContact O-C 3.56Å; D17-F20 PolarHBondContact OD1-N 2.84Å; L18-F20 VanDerWaalsContact C-N 3.32Å; F20-S26 VanDerWaalsContact CD2-OG 3.28Å; F20-S26 WeakPolarHBondContact CD2-OG 3.21Å; F20-S26 WeakPolarHBondContact CE2-OG 3.29Å; F20-S26 WeakPolarHBondContact CG-OG 3.32Å; F20-S26 VanDerWaalsContact CZ-O 3.29Å; F20-S26 WeakPolarHBondContact CZ-O 3.37Å; F20-W44 HydrophobicContact CE1-CH2 4.21Å; F20-K154 HydrophobicContact CD1-CG 4.3Å; F20-K154 HydrophobicContact CE1-CG 4.05Å; F20-A157 HydrophobicContact CZ-CB 4.02Å; F20-K158 HydrophobicContact CB-CB 4.15Å; F20-K158 HydrophobicContact CB-CD 3.71Å; F20-K158 HydrophobicContact CB-CG 3.83Å; F20-K158 HydrophobicContact CD1-CB 4.24Å; F20-K158 HydrophobicContact CD2-CB 3.7Å; F20-K158 HydrophobicContact CD2-CG 3.95Å; F20-K158 VanDerWaalsContact CE2-CA 3.49Å; F20-K158 HydrophobicContact CE2-CB 4.09Å; F20-K158 HydrophobicContact CG-CB 3.77Å; F20-K158 HydrophobicContact CG-CD 4.28Å; F20-K158 HydrophobicContact CG-CG 3.97Å; F20-K158 HydrophobicContact CZ-CB 4.49Å; F20-Y163 HydrophobicContact CE1-CD2 4.35Å; F20-Y163 HydrophobicContact CE1-CE2 4.02Å; F20-Y163 HydrophobicContact CZ-CD2 4.16Å; F20-Y163 HydrophobicContact CZ-CE2 4.27Å
21P95.1Very high88.4Confident44 Ų4463.8 Ų63.829%0.28638%0.378SS..  trans-66.9161-171.828.1-36000112.6T23 S26P21-T23 HydrophobicContact CB-CG2 4.39Å; P21-T23 WeakPolarHBondContact CG-OG1 3.25Å; P21-T23 PolarHBondContact O-N 2.6Å; P21-S26 WeakPolarHBondContact O-CB 3.49Å; P21-S26 PolarHBondContact O-OG 2.87Å
22I94.1Very high89.9Confident72 Ų7264.8 Ų64.837%0.36938%0.377SS..SBendtrans-7841.3177.957.8165.9000113.2W44 R128I22-W44 HydrophobicContact CB-CB 4.02Å; I22-W44 HydrophobicContact CB-CD2 3.76Å; I22-W44 HydrophobicContact CB-CE3 4.39Å; I22-W44 HydrophobicContact CB-CG 3.58Å; I22-W44 HydrophobicContact CG2-CB 3.9Å; I22-W44 HydrophobicContact CG2-CD2 3.63Å; I22-W44 HydrophobicContact CG2-CE3 3.77Å; I22-W44 HydrophobicContact CG2-CG 3.72Å; I22-W44 HydrophobicContact CG2-CZ3 4.44Å; I22-W44 PolarHBondContact O-NE1 3.43Å; I22-R128 HydrophobicContact CG2-CB 4.08Å
23T91.6Very high91Very high67 Ų6760.8 Ų60.841%0.41135%0.35SS..SBendtrans-116167.7-176.452.30000111P21 S25 S26P21-T23 HydrophobicContact CB-CG2 4.39Å; P21-T23 WeakPolarHBondContact CG-OG1 3.25Å; P21-T23 PolarHBondContact O-N 2.6Å; T23-S25 PolarHBondContact O-N 2.95Å; T23-S25 VanDerWaalsContact O-N 3.08Å; T23-S25 PolarHBondContact OG1-OG 3.13Å; T23-S26 PolarHBondContact O-N 2.78Å
24D91.1Very high91.1Very high82 Ų8259.2 Ų59.244%0.43934%0.337SS..Hα-helixtrans-54.6-29.1178.5-73.7-8.4000113.1S26 L27 F28 H39D24-S26 PolarHBondContact O-N 2.89Å; D24-L27 PolarHBondContact O-N 3.44Å; D24-F28 HydrophobicContact CB-CD2 3.93Å; D24-F28 HydrophobicContact CB-CE2 4.42Å; D24-F28 PolarHBondContact O-N 2.76Å; D24-H39 IonicContact OD2-CD2 2.83Å
25S91.9Very high90.7Very high72 Ų7256.4 Ų56.450%0.50332%0.323SS..Hα-helixtrans-60.7-24.6175.258.70000114.8T23T23-S25 PolarHBondContact O-N 2.95Å; T23-S25 VanDerWaalsContact O-N 3.08Å; T23-S25 PolarHBondContact OG1-OG 3.13Å
26S95.7Very high90.2Very high3 Ų353.9 Ų53.92%0.02132%0.315CS..Hα-helixtrans-88.8-18.7176.3-800000112.5F20 P21 T23 D24 S162 Y163F20-S26 VanDerWaalsContact CD2-OG 3.28Å; F20-S26 WeakPolarHBondContact CD2-OG 3.21Å; F20-S26 WeakPolarHBondContact CE2-OG 3.29Å; F20-S26 WeakPolarHBondContact CG-OG 3.32Å; F20-S26 VanDerWaalsContact CZ-O 3.29Å; F20-S26 WeakPolarHBondContact CZ-O 3.37Å; P21-S26 WeakPolarHBondContact O-CB 3.49Å; P21-S26 PolarHBondContact O-OG 2.87Å; T23-S26 PolarHBondContact O-N 2.78Å; D24-S26 PolarHBondContact O-N 2.89Å; S26-S162 CarbonylContact O-C 3.52Å; S26-S162 VanDerWaalsContact O-CA 3.28Å; S26-S162 WeakPolarHBondContact O-CA 3.31Å; S26-S162 WeakPolarHBondContact O-CB 3.27Å; S26-Y163 WeakPolarHBondContact O-CD2 3.19Å; S26-Y163 PolarHBondContact O-N 3.37Å
27L93.7Very high89.7Confident1 Ų156.3 Ų56.31%0.00533%0.327CS..Hα-helixtrans-91.5-48.3176.4-64.2170.1000111D24 I42 W44 P130 F138 Y163 E164D24-L27 PolarHBondContact O-N 3.44Å; L27-I42 HydrophobicContact CD1-CB 4Å; L27-I42 HydrophobicContact CD1-CD1 3.97Å; L27-I42 HydrophobicContact CD1-CG2 3.76Å; L27-I42 HydrophobicContact CD2-CD1 4.38Å; L27-I42 HydrophobicContact CD2-CG2 4.37Å; L27-W44 HydrophobicContact CD1-CZ2 4.36Å; L27-W44 HydrophobicContact CD2-CH2 4.36Å; L27-W44 HydrophobicContact CD2-CZ2 3.82Å; L27-W44 HydrophobicContact CG-CZ2 3.87Å; L27-P130 HydrophobicContact CD2-CB 4Å; L27-P130 HydrophobicContact CD2-CG 3.69Å; L27-F138 HydrophobicContact CD2-CE2 3.79Å; L27-F138 HydrophobicContact CD2-CZ 4.1Å; L27-Y163 HydrophobicContact CD2-CD2 4.01Å; L27-E164 WeakPolarHBondContact O-CB 3.34Å; L27-E164 PolarHBondContact O-N 3.03Å
28F91.8Very high89.1Confident11 Ų1157.4 Ų57.45%0.04833%0.332CS..  trans-118154.6-168.4-46.6-63.3000110.9D24 I35 H39 I42D24-F28 HydrophobicContact CB-CD2 3.93Å; D24-F28 HydrophobicContact CB-CE2 4.42Å; D24-F28 PolarHBondContact O-N 2.76Å; F28-I35 HydrophobicContact CD1-CD1 4.23Å; F28-I35 HydrophobicContact CD1-CG1 4.44Å; F28-I35 HydrophobicContact CE1-CD1 4.22Å; F28-I35 HydrophobicContact CE1-CG1 4.35Å; F28-I35 WeakPolarHBondContact CE1-O 3.36Å; F28-H39 AromaticContact CD1-CE1 3.86Å; F28-H39 AromaticContact CD2-CD2 3.6Å; F28-H39 AromaticContact CD2-CE1 3.29Å; F28-H39 WeakPolarHBondContact CD2-CE1 3.22Å; F28-H39 AromaticContact CD2-ND1 3.84Å; F28-H39 AromaticContact CD2-NE2 3.11Å; F28-H39 WeakPolarHBondContact CD2-NE2 3.19Å; F28-H39 AromaticContact CE2-CD2 3.63Å; F28-H39 AromaticContact CE2-CE1 3.69Å; F28-H39 AromaticContact CE2-CG 3.71Å; F28-H39 AromaticContact CE2-ND1 3.74Å; F28-H39 AromaticContact CE2-NE2 3.64Å; F28-H39 AromaticContact CG-CE1 3.37Å; F28-H39 WeakPolarHBondContact CG-CE1 3.38Å; F28-H39 AromaticContact CG-NE2 3.6Å; F28-H39 AromaticContact CZ-ND1 3.93Å; F28-I42 HydrophobicContact CZ-CD1 4.2Å
29S85.9Confident88.4Confident50 Ų5054.1 Ų54.135%0.3531%0.312SS..SBendtrans-130.1-69.1-178.258.50000112E164S29-E164 WeakPolarHBondContact CA-OE2 3.34Å; S29-E164 PolarHBondContact N-OE2 3.36Å; S29-E164 PolarHBondContact OG-OE2 3.33Å
30D82.9Confident87.8Confident72 Ų7251.1 Ų51.139%0.38531%0.314SS..SBendtrans-117.11.8177.163.91.2000112.4S32 E164 R394D30-S32 VanDerWaalsContact CG-OG 3.25Å; D30-S32 PolarHBondContact O-N 2.82Å; D30-S32 WeakPolarHBondContact OD1-CB 3.41Å; D30-S32 PolarHBondContact OD1-N 2.89Å; D30-S32 VanDerWaalsContact OD1-N 3.14Å; D30-S32 PolarHBondContact OD1-OG 3.04Å; D30-S32 PolarHBondContact OD2-OG 2.85Å; D30-E164 PolarHBondContact N-OE2 2.96Å; D30-E164 VanDerWaalsContact N-OE2 3.09Å; D30-R394 IonicContact OD1-NH1 3.74Å; D30-R394 IonicContact OD2-CZ 2.87Å; D30-R394 IonicContact OD2-NH1 2.68Å; D30-R394 PolarHBondContact OD2-NH1 3.19Å; D30-R394 IonicContact OD2-NH2 3.4Å
31S83.1Confident87.3Confident61 Ų6156.6 Ų56.643%0.42734%0.34SS..  trans56.828.6-179.9-58.20000113.1T33 E164S31-T33 VanDerWaalsContact C-N 3.28Å; S31-E164 WeakPolarHBondContact CA-OE1 3.26Å; S31-E164 PolarHBondContact N-OE1 3.32Å; S31-E164 PolarHBondContact N-OE2 3.23Å
32S80Confident87.2Confident79 Ų7955.6 Ų55.655%0.55233%0.332SS*.  trans-83.2-3.7-178.763.50000113.7D30 E164D30-S32 VanDerWaalsContact CG-OG 3.25Å; D30-S32 PolarHBondContact O-N 2.82Å; D30-S32 WeakPolarHBondContact OD1-CB 3.41Å; D30-S32 PolarHBondContact OD1-N 2.89Å; D30-S32 VanDerWaalsContact OD1-N 3.14Å; D30-S32 PolarHBondContact OD1-OG 3.04Å; D30-S32 PolarHBondContact OD2-OG 2.85Å; S32-E164 PolarHBondContact N-OE1 2.97Å; S32-E164 VanDerWaalsContact N-OE1 3.09Å
33T84.5Confident87.2Confident15 Ų1555.2 Ų55.29%0.09233%0.333CS..SBendtrans-115.1160.5-173.469.20000112.3S31 I35 A36 E164 W167S31-T33 VanDerWaalsContact C-N 3.28Å; T33-I35 PolarHBondContact O-N 3.37Å; T33-I35 VanDerWaalsContact O-N 3.11Å; T33-I35 WeakPolarHBondContact OG1-CG1 3.28Å; T33-A36 VanDerWaalsContact O-CB 3.23Å; T33-A36 WeakPolarHBondContact O-CB 2.88Å; T33-A36 PolarHBondContact O-N 2.99Å; T33-E164 WeakPolarHBondContact CB-OE1 3.4Å; T33-E164 HydrophobicContact CG2-CG 3.64Å; T33-E164 PolarHBondContact N-OE1 3.12Å; T33-E164 VanDerWaalsContact N-OE1 3.12Å; T33-E164 WeakPolarHBondContact OG1-CG 3.43Å; T33-E164 PolarHBondContact OG1-OE1 3.14Å; T33-W167 HydrophobicContact CG2-CB 3.69Å; T33-W167 HydrophobicContact CG2-CD2 3.96Å; T33-W167 HydrophobicContact CG2-CG 3.52Å
34P84.1Confident87.5Confident74 Ų7453.9 Ų53.948%0.48132%0.32SS..G310 helixtrans-56.9-26.3177.5-27.436.3000114.6A36 Q37 W167P34-A36 PolarHBondContact O-N 2.92Å; P34-Q37 PolarHBondContact O-N 3.02Å; P34-W167 HydrophobicContact CB-CH2 4.12Å; P34-W167 VanDerWaalsContact CD-CZ2 3.47Å; P34-W167 HydrophobicContact CG-CH2 3.69Å; P34-W167 HydrophobicContact CG-CZ2 3.74Å; P34-W167 HydrophobicContact CG-CZ3 4.47Å
35I86.3Confident87.7Confident4 Ų453.9 Ų53.92%0.02131%0.314CS..G310 helixtrans-66.2-19.6178.563.6154000112.4F28 T33 Q37 L38 L71 F138 E164 W167F28-I35 HydrophobicContact CD1-CD1 4.23Å; F28-I35 HydrophobicContact CD1-CG1 4.44Å; F28-I35 HydrophobicContact CE1-CD1 4.22Å; F28-I35 HydrophobicContact CE1-CG1 4.35Å; F28-I35 WeakPolarHBondContact CE1-O 3.36Å; T33-I35 PolarHBondContact O-N 3.37Å; T33-I35 VanDerWaalsContact O-N 3.11Å; T33-I35 WeakPolarHBondContact OG1-CG1 3.28Å; I35-Q37 PolarHBondContact O-N 3.28Å; I35-Q37 VanDerWaalsContact O-N 3.09Å; I35-L38 HydrophobicContact CB-CD1 4.32Å; I35-L38 VanDerWaalsContact O-CB 3.29Å; I35-L38 WeakPolarHBondContact O-CB 3.37Å; I35-L38 WeakPolarHBondContact O-CG 3.42Å; I35-L38 PolarHBondContact O-N 3.21Å; I35-L71 HydrophobicContact CD1-CD1 4Å; I35-L71 HydrophobicContact CG2-CD1 4.38Å; I35-F138 HydrophobicContact CG2-CE1 4.5Å; I35-E164 HydrophobicContact CD1-CB 3.91Å; I35-E164 HydrophobicContact CD1-CG 4.42Å; I35-W167 HydrophobicContact CG2-CE3 4.24Å; I35-W167 HydrophobicContact CG2-CZ3 3.92Å
36A84.9Confident88Confident18 Ų1851.4 Ų51.415%0.14929%0.294CS..G310 helixtrans-60-19174.900000113.2T33 P34 L38 H39T33-A36 VanDerWaalsContact O-CB 3.23Å; T33-A36 WeakPolarHBondContact O-CB 2.88Å; T33-A36 PolarHBondContact O-N 2.99Å; P34-A36 PolarHBondContact O-N 2.92Å; A36-L38 PolarHBondContact O-N 2.76Å; A36-H39 PolarHBondContact O-ND1 3.26Å
37Q84.8Confident88Confident163 Ų16351.3 Ų51.376%0.76229%0.293SS*.G310 helixtrans-70.7-13.9174.5-62.2177.87.900112.9P34 I35 H39P34-Q37 PolarHBondContact O-N 3.02Å; I35-Q37 PolarHBondContact O-N 3.28Å; I35-Q37 VanDerWaalsContact O-N 3.09Å; Q37-H39 VanDerWaalsContact C-N 3.3Å; Q37-H39 PolarHBondContact O-N 3.22Å
38L83.9Confident88.1Confident26 Ų2655.1 Ų55.114%0.13631%0.311CS..G310 helixtrans-88.410.2-177.7-52.4175.6000113.4I35 A36 G40 E41 I42 L70 M132I35-L38 HydrophobicContact CB-CD1 4.32Å; I35-L38 VanDerWaalsContact O-CB 3.29Å; I35-L38 WeakPolarHBondContact O-CB 3.37Å; I35-L38 WeakPolarHBondContact O-CG 3.42Å; I35-L38 PolarHBondContact O-N 3.21Å; A36-L38 PolarHBondContact O-N 2.76Å; L38-G40 PolarHBondContact O-N 2.8Å; L38-E41 PolarHBondContact O-N 3.11Å; L38-E41 VanDerWaalsContact O-N 3.13Å; L38-I42 HydrophobicContact CB-CD1 3.83Å; L38-I42 HydrophobicContact CB-CG1 4.14Å; L38-I42 HydrophobicContact CD1-CD1 4.22Å; L38-L70 HydrophobicContact CD1-CD1 3.82Å; L38-M132 HydrophobicContact CD1-CE 4.43Å; L38-M132 HydrophobicContact CD2-CE 4.21Å; L38-M132 HydrophobicContact CD2-SD 4.01Å
39H80.7Confident88.2Confident81 Ų8160 Ų6038%0.37533%0.334SS..THydrogen-bonded Turntrans-57.1127.7178.9-8887000111D24 F28 A36 Q37 E41D24-H39 IonicContact OD2-CD2 2.83Å; F28-H39 AromaticContact CD1-CE1 3.86Å; F28-H39 AromaticContact CD2-CD2 3.6Å; F28-H39 AromaticContact CD2-CE1 3.29Å; F28-H39 WeakPolarHBondContact CD2-CE1 3.22Å; F28-H39 AromaticContact CD2-ND1 3.84Å; F28-H39 AromaticContact CD2-NE2 3.11Å; F28-H39 WeakPolarHBondContact CD2-NE2 3.19Å; F28-H39 AromaticContact CE2-CD2 3.63Å; F28-H39 AromaticContact CE2-CE1 3.69Å; F28-H39 AromaticContact CE2-CG 3.71Å; F28-H39 AromaticContact CE2-ND1 3.74Å; F28-H39 AromaticContact CE2-NE2 3.64Å; F28-H39 AromaticContact CG-CE1 3.37Å; F28-H39 WeakPolarHBondContact CG-CE1 3.38Å; F28-H39 AromaticContact CG-NE2 3.6Å; F28-H39 AromaticContact CZ-ND1 3.93Å; A36-H39 PolarHBondContact O-ND1 3.26Å; Q37-H39 VanDerWaalsContact C-N 3.3Å; Q37-H39 PolarHBondContact O-N 3.22Å; H39-E41 PolarHBondContact O-N 3.15Å
40G81.1Confident88.7Confident75 Ų7559.5 Ų59.577%0.77333%0.327SS*.THydrogen-bonded Turntrans79.2-7.6-18000000115.7L38L38-G40 PolarHBondContact O-N 2.8Å
41E86.4Confident89.2Confident119 Ų11957.6 Ų57.656%0.55632%0.319SS*.THydrogen-bonded Turntrans-91.8-22.1176.8-60.9-172.6-17600112.7L38 H39 M132L38-E41 PolarHBondContact O-N 3.11Å; L38-E41 VanDerWaalsContact O-N 3.13Å; H39-E41 PolarHBondContact O-N 3.15Å; E41-M132 HydrophobicContact CB-CG 4.49Å; E41-M132 HydrophobicContact CB-SD 4.06Å
42I93.3Very high89.6Confident23 Ų2366.5 Ų66.512%0.11834%0.343CS..  trans-86.1127.3-174-63.1174.8000111.2L27 F28 L38 P130 M132L27-I42 HydrophobicContact CD1-CB 4Å; L27-I42 HydrophobicContact CD1-CD1 3.97Å; L27-I42 HydrophobicContact CD1-CG2 3.76Å; L27-I42 HydrophobicContact CD2-CD1 4.38Å; L27-I42 HydrophobicContact CD2-CG2 4.37Å; F28-I42 HydrophobicContact CZ-CD1 4.2Å; L38-I42 HydrophobicContact CB-CD1 3.83Å; L38-I42 HydrophobicContact CB-CG1 4.14Å; L38-I42 HydrophobicContact CD1-CD1 4.22Å; I42-P130 HydrophobicContact CG2-CB 3.73Å; I42-M132 HydrophobicContact CG1-CG 4.23Å; I42-M132 HydrophobicContact CG1-SD 4.47Å
43T94.4Very high90.3Very high64 Ų6467.2 Ų67.239%0.39335%0.348SS..EExtended strand (participates in β ladder)trans-108.7154.917061.70000110.6P130 C131T43-P130 CarbonylContact O-C 3.41Å; T43-C131 PolarHBondContact N-O 2.89Å; T43-C131 PolarHBondContact O-N 2.79Å; T43-C131 PolarHBondContact OG1-O 3.2Å
44W96.2Very high90.8Very high38 Ų3867.3 Ų67.314%0.14435%0.349CS..EExtended strand (participates in β ladder)trans-106122.6177.7-69.180.7000110.3F20 I22 L27 R128 L129 P130 Y163F20-W44 HydrophobicContact CE1-CH2 4.21Å; I22-W44 HydrophobicContact CB-CB 4.02Å; I22-W44 HydrophobicContact CB-CD2 3.76Å; I22-W44 HydrophobicContact CB-CE3 4.39Å; I22-W44 HydrophobicContact CB-CG 3.58Å; I22-W44 HydrophobicContact CG2-CB 3.9Å; I22-W44 HydrophobicContact CG2-CD2 3.63Å; I22-W44 HydrophobicContact CG2-CE3 3.77Å; I22-W44 HydrophobicContact CG2-CG 3.72Å; I22-W44 HydrophobicContact CG2-CZ3 4.44Å; I22-W44 PolarHBondContact O-NE1 3.43Å; L27-W44 HydrophobicContact CD1-CZ2 4.36Å; L27-W44 HydrophobicContact CD2-CH2 4.36Å; L27-W44 HydrophobicContact CD2-CZ2 3.82Å; L27-W44 HydrophobicContact CG-CZ2 3.87Å; W44-R128 HydrophobicContact CB-CB 4.3Å; W44-R128 HydrophobicContact CE3-CB 4.19Å; W44-R128 WeakPolarHBondContact CZ3-O 3.19Å; W44-L129 WeakPolarHBondContact CA-O 3.28Å; W44-P130 HydrophobicContact CD2-CG 4.47Å; W44-P130 HydrophobicContact CE3-CG 4.14Å; W44-P130 HydrophobicContact CH2-CG 3.93Å; W44-P130 HydrophobicContact CZ2-CG 4.24Å; W44-P130 HydrophobicContact CZ3-CG 3.86Å; W44-Y163 HydrophobicContact CH2-CE2 4.11Å
45R96.9Very high91.4Very high82 Ų8265.1 Ų65.131%0.30934%0.335SS..EExtended strand (participates in β ladder)trans-130.1144.9-177.1-65-167.8179.3-1473112.6E49 I50 R128 L129 C131 S134R45-E49 VanDerWaalsContact CA-OE2 3.24Å; R45-E49 WeakPolarHBondContact CA-OE2 3.34Å; R45-E49 HydrophobicContact CB-CB 4.29Å; R45-I50 HydrophobicContact CB-CD1 4.22Å; R45-I50 HydrophobicContact CB-CG1 3.95Å; R45-R128 CarbonylContact O-C 3.56Å; R45-R128 WeakPolarHBondContact O-CA 3.39Å; R45-L129 PolarHBondContact N-O 2.82Å; R45-L129 PolarHBondContact O-N 2.97Å; R45-C131 HydrophobicContact CG-CB 4.34Å; R45-S134 PolarHBondContact NH1-OG 2.91Å; R45-S134 PolarHBondContact NH2-OG 2.97Å
46R96.6Very high91.7Very high21 Ų2165.2 Ų65.28%0.07934%0.336CS..  trans-81.2155.2171.6-62.3-170.6-174-97.53.1110.4F15 Q48 E49 I50 G108 D127 R128F15-R46 PolarHBondContact O-NH1 3.1Å; F15-R46 PolarHBondContact O-NH2 3.13Å; R46-Q48 PolarHBondContact O-N 2.95Å; R46-Q48 VanDerWaalsContact O-N 3.12Å; R46-E49 PolarHBondContact N-OE2 2.92Å; R46-E49 WeakPolarHBondContact O-CA 3.25Å; R46-E49 WeakPolarHBondContact O-CB 3.49Å; R46-E49 PolarHBondContact O-N 2.81Å; R46-I50 PolarHBondContact O-N 2.83Å; R46-G108 PolarHBondContact NH1-O 2.78Å; R46-D127 VanDerWaalsContact CD-OD1 3.31Å; R46-D127 WeakPolarHBondContact CD-OD1 3.49Å; R46-D127 WeakPolarHBondContact CG-OD1 3.29Å; R46-D127 IonicContact CZ-OD1 3.61Å; R46-D127 IonicContact NE-OD1 3Å; R46-D127 IonicContact NH1-OD1 3.22Å; R46-D127 PolarHBondContact NH1-OD1 3.03Å; R46-R128 HydrophobicContact CG-CG 3.73Å
47P96.7Very high92.2Very high0 Ų067.3 Ų67.30%034%0.341CS..Hα-helixtrans-53.7-33.1179.6-3641.7000115.3E49 I50 C51 P54 W101 D127 L129 F147P47-E49 PolarHBondContact O-N 3.4Å; P47-I50 PolarHBondContact O-N 2.85Å; P47-I50 VanDerWaalsContact O-N 3.15Å; P47-C51 PolarHBondContact O-N 3.35Å; P47-P54 HydrophobicContact CB-CB 3.52Å; P47-P54 HydrophobicContact CB-CG 4.08Å; P47-W101 HydrophobicContact CB-CD2 4.37Å; P47-W101 HydrophobicContact CB-CZ2 3.92Å; P47-W101 HydrophobicContact CG-CH2 4.4Å; P47-W101 HydrophobicContact CG-CZ2 3.52Å; P47-D127 WeakPolarHBondContact CD-O 3.19Å; P47-D127 HydrophobicContact CG-CB 4.48Å; P47-L129 HydrophobicContact CG-CD1 4.36Å; P47-F147 HydrophobicContact CB-CD1 4.11Å; P47-F147 HydrophobicContact CB-CD2 3.87Å; P47-F147 HydrophobicContact CB-CE1 3.99Å; P47-F147 HydrophobicContact CB-CE2 3.77Å; P47-F147 HydrophobicContact CB-CG 4.05Å; P47-F147 HydrophobicContact CB-CZ 3.82Å; P47-F147 HydrophobicContact CG-CB 4.46Å; P47-F147 HydrophobicContact CG-CD1 3.84Å; P47-F147 HydrophobicContact CG-CD2 4.25Å; P47-F147 HydrophobicContact CG-CE1 4.09Å; P47-F147 HydrophobicContact CG-CG 3.92Å; P47-F147 HydrophobicContact CG-CZ 4.42Å
48Q95.2Very high92.6Very high82 Ų8260.4 Ų60.438%0.38331%0.311SS..Hα-helixtrans-66.1-20.9175-58.7104.3-50.500113.9R46 P54 W101 Y106R46-Q48 PolarHBondContact O-N 2.95Å; R46-Q48 VanDerWaalsContact O-N 3.12Å; Q48-P54 HydrophobicContact CG-CG 4.18Å; Q48-W101 VanDerWaalsContact OE1-CD1 3.29Å; Q48-Y106 VanDerWaalsContact NE2-CZ 3.3Å; Q48-Y106 PolarHBondContact NE2-OH 3.39Å; Q48-Y106 PolarHBondContact OE1-OH 3.14Å
49E95Very high92.7Very high114 Ų11466.8 Ų66.853%0.53335%0.351SS..Hα-helixtrans-90.7-13.2177.6-56.5170.4150.300111.8R45 R46 P47R45-E49 VanDerWaalsContact CA-OE2 3.24Å; R45-E49 WeakPolarHBondContact CA-OE2 3.34Å; R45-E49 HydrophobicContact CB-CB 4.29Å; R46-E49 PolarHBondContact N-OE2 2.92Å; R46-E49 WeakPolarHBondContact O-CA 3.25Å; R46-E49 WeakPolarHBondContact O-CB 3.49Å; R46-E49 PolarHBondContact O-N 2.81Å; P47-E49 PolarHBondContact O-N 3.4Å
50I95.3Very high93.1Very high39 Ų3966.8 Ų66.820%0.235%0.354CS..Hα-helixtrans-97.3-43.1-178.6-59.6169000110.2R45 R46 P47 L136 F147R45-I50 HydrophobicContact CB-CD1 4.22Å; R45-I50 HydrophobicContact CB-CG1 3.95Å; R46-I50 PolarHBondContact O-N 2.83Å; P47-I50 PolarHBondContact O-N 2.85Å; P47-I50 VanDerWaalsContact O-N 3.15Å; I50-L136 HydrophobicContact CD1-CD2 3.89Å; I50-F147 HydrophobicContact CB-CE1 4.44Å; I50-F147 HydrophobicContact CB-CZ 4.3Å; I50-F147 HydrophobicContact CD1-CE1 4.03Å; I50-F147 HydrophobicContact CG2-CE1 4.29Å; I50-F147 HydrophobicContact CG2-CZ 4.2Å
51C93.9Very high93.3Very high31 Ų3166.6 Ų66.621%0.20935%0.345CS..  trans-144.7163178.583.50000113.2P47P47-C51 PolarHBondContact O-N 3.35Å
52R92.3Very high93.1Very high249 Ų24966.2 Ų66.294%0.9435%0.347SS*.SBendtrans-70.6-33.2-173.7-68.2-176.1178.9173.3-0114.3
53S93.4Very high92.8Very high94 Ų9468.7 Ų68.766%0.65736%0.36SS*.SBendtrans-13667.8-171.4-56.90000111S145S53-S145 WeakPolarHBondContact O-CB 3.39Å
54P95.9Very high92.7Very high16 Ų1665.8 Ų65.810%0.10434%0.343CS..  trans-68139.2-178.527.2-33.2000111.5P47 Q48 W101 S145 F147P47-P54 HydrophobicContact CB-CB 3.52Å; P47-P54 HydrophobicContact CB-CG 4.08Å; Q48-P54 HydrophobicContact CG-CG 4.18Å; P54-W101 HydrophobicContact CB-CB 4.41Å; P54-W101 HydrophobicContact CB-CD2 3.83Å; P54-W101 HydrophobicContact CB-CE3 4Å; P54-W101 HydrophobicContact CB-CG 4.02Å; P54-W101 HydrophobicContact CG-CB 3.64Å; P54-W101 HydrophobicContact CG-CD2 3.95Å; P54-W101 HydrophobicContact CG-CE3 4.46Å; P54-W101 HydrophobicContact CG-CG 3.57Å; P54-S145 WeakPolarHBondContact CA-O 3.4Å; P54-F147 HydrophobicContact CB-CD2 3.9Å; P54-F147 HydrophobicContact CB-CE2 3.57Å
55S95.3Very high92.4Very high28 Ų2865.1 Ų65.120%0.19634%0.341CS..BIsolated β-bridgetrans-133.6156.3174.974.90000110.5F57 S145 A146 F147S55-F57 WeakPolarHBondContact CB-O 3.44Å; S55-F57 PolarHBondContact OG-O 3.12Å; S55-S145 PolarHBondContact N-O 2.99Å; S55-A146 WeakPolarHBondContact O-CA 3.33Å; S55-F147 PolarHBondContact O-N 2.93Å
56L94.3Very high92.1Very high6 Ų661.3 Ų61.33%0.03133%0.327CS..SBendtrans-73.9-55.3-177.8-172.262.4000108.1F94 Q98 W101 F110 F147 W148 L151L56-F94 HydrophobicContact CD2-CD1 4.25Å; L56-Q98 HydrophobicContact CD2-CB 4.34Å; L56-W101 HydrophobicContact CB-CZ3 4.07Å; L56-W101 HydrophobicContact CD1-CH2 4.17Å; L56-W101 HydrophobicContact CD1-CZ3 4.44Å; L56-F110 HydrophobicContact CD1-CD1 4.13Å; L56-F110 HydrophobicContact CD1-CE1 4.02Å; L56-F147 PolarHBondContact O-N 3.06Å; L56-W148 HydrophobicContact CD1-CB 4.25Å; L56-W148 HydrophobicContact CG-CB 4.29Å; L56-W148 VanDerWaalsContact O-CB 3.25Å; L56-W148 WeakPolarHBondContact O-CB 3.35Å; L56-W148 PolarHBondContact O-N 2.77Å; L56-L151 HydrophobicContact CD1-CD1 3.78Å
57F94.7Very high91.9Very high62 Ų6261.6 Ų61.627%0.27233%0.329SS..SBendtrans-112.1149172.3-64.8-84.7000110S55 L90 F94 W148S55-F57 WeakPolarHBondContact CB-O 3.44Å; S55-F57 PolarHBondContact OG-O 3.12Å; F57-L90 HydrophobicContact CE1-CD1 3.94Å; F57-L90 HydrophobicContact CE1-CD2 4.07Å; F57-L90 HydrophobicContact CE1-CG 4.4Å; F57-L90 HydrophobicContact CZ-CD1 3.96Å; F57-L90 HydrophobicContact CZ-CD2 4.28Å; F57-L90 HydrophobicContact CZ-CG 4.27Å; F57-F94 AromaticContact CE2-CD1 3.95Å; F57-F94 HydrophobicContact CE2-CD1 3.95Å; F57-F94 HydrophobicContact CE2-CE1 4.3Å; F57-F94 HydrophobicContact CE2-CG 4.19Å; F57-F94 HydrophobicContact CZ-CB 4.47Å; F57-F94 AromaticContact CZ-CD1 3.79Å; F57-F94 HydrophobicContact CZ-CD1 3.79Å; F57-F94 AromaticContact CZ-CD2 3.97Å; F57-F94 HydrophobicContact CZ-CD2 3.97Å; F57-F94 AromaticContact CZ-CE1 3.89Å; F57-F94 HydrophobicContact CZ-CE1 3.89Å; F57-F94 HydrophobicContact CZ-CE2 4.12Å; F57-F94 AromaticContact CZ-CG 3.82Å; F57-F94 HydrophobicContact CZ-CG 3.82Å; F57-F94 HydrophobicContact CZ-CZ 4.09Å; F57-W148 HydrophobicContact CD1-CB 3.88Å; F57-W148 AromaticContact CD1-CD1 3.65Å; F57-W148 HydrophobicContact CD1-CD2 4.1Å; F57-W148 AromaticContact CD1-CG 3.57Å; F57-W148 HydrophobicContact CD1-CG 3.57Å; F57-W148 HydrophobicContact CE1-CB 3.51Å; F57-W148 AromaticContact CE1-CD1 3.83Å; F57-W148 AromaticContact CE1-CD2 3.48Å; F57-W148 HydrophobicContact CE1-CD2 3.48Å; F57-W148 VanDerWaalsContact CE1-CD2 3.48Å; F57-W148 AromaticContact CE1-CE3 3.9Å; F57-W148 HydrophobicContact CE1-CE3 3.9Å; F57-W148 AromaticContact CE1-CG 3.29Å; F57-W148 HydrophobicContact CE1-CG 3.29Å; F57-W148 HydrophobicContact CE2-CB 4.19Å; F57-W148 HydrophobicContact CG-CB 4.37Å; F57-W148 HydrophobicContact CG-CG 4.45Å; F57-W148 HydrophobicContact CZ-CB 3.68Å; F57-W148 HydrophobicContact CZ-CD2 4.24Å; F57-W148 HydrophobicContact CZ-CE3 4.37Å; F57-W148 AromaticContact CZ-CG 3.97Å; F57-W148 HydrophobicContact CZ-CG 3.97Å
58P92.6Very high91.6Very high18 Ų1862.7 Ų62.712%0.11733%0.334CS..  trans-77.3156171.930.6-28.5000110.9N60 L63 A64 A146P58-N60 VanDerWaalsContact C-N 3.26Å; P58-N60 WeakPolarHBondContact CG-O 3.39Å; P58-N60 PolarHBondContact O-N 3.41Å; P58-L63 HydrophobicContact CB-CB 4.15Å; P58-L63 HydrophobicContact CG-CB 4.11Å; P58-A64 HydrophobicContact CG-CB 3.64Å; P58-A146 HydrophobicContact CB-CB 4.06Å; P58-A146 HydrophobicContact CG-CB 4.03Å
59T87.4Confident91.5Very high160 Ų16060 Ų6098%0.98233%0.328SS*.SBendtrans-62.2-34.4176.4-44.70000112.6
60N88.3Confident91.3Very high81 Ų8158.7 Ų58.743%0.43332%0.324SS..SBendtrans-97.6116.2175.1-177.8-10.2000109.7P58 N62 L63P58-N60 VanDerWaalsContact C-N 3.26Å; P58-N60 WeakPolarHBondContact CG-O 3.39Å; P58-N60 PolarHBondContact O-N 3.41Å; N60-N62 PolarHBondContact O-N 3.21Å; N60-N62 WeakPolarHBondContact OD1-CB 3.26Å; N60-N62 PolarHBondContact OD1-N 3.45Å; N60-L63 HydrophobicContact CB-CD1 4.1Å; N60-L63 HydrophobicContact CB-CG 4.13Å; N60-L63 WeakPolarHBondContact O-CB 3.42Å; N60-L63 PolarHBondContact O-N 3.47Å
61A84.5Confident91Very high71 Ų7156.9 Ų56.959%0.58732%0.315SS*.G310 helixtrans-57.4-31.7179.900000113.4L63 A64A61-L63 PolarHBondContact O-N 2.95Å; A61-A64 WeakPolarHBondContact O-CB 3.27Å; A61-A64 PolarHBondContact O-N 3.23Å
62N82.9Confident90.7Very high111 Ų11156.1 Ų56.159%0.59431%0.312SS*.G310 helixtrans-64.4-23.1176.5-66.7-15.9000112.3N60 A64 H65N60-N62 PolarHBondContact O-N 3.21Å; N60-N62 WeakPolarHBondContact OD1-CB 3.26Å; N60-N62 PolarHBondContact OD1-N 3.45Å; N62-A64 VanDerWaalsContact C-N 3.33Å; N62-H65 PolarHBondContact O-CD2 2.84Å; N62-H65 VanDerWaalsContact O-CD2 3.27Å
63L88Confident90.6Very high76 Ų7644.2 Ų44.240%0.39827%0.268SS..G310 helixtrans-86.8-5.4175.5-59.1179000113P58 N60 A61 H65 H142 S143P58-L63 HydrophobicContact CB-CB 4.15Å; P58-L63 HydrophobicContact CG-CB 4.11Å; N60-L63 HydrophobicContact CB-CD1 4.1Å; N60-L63 HydrophobicContact CB-CG 4.13Å; N60-L63 WeakPolarHBondContact O-CB 3.42Å; N60-L63 PolarHBondContact O-N 3.47Å; A61-L63 PolarHBondContact O-N 2.95Å; L63-H65 VanDerWaalsContact C-N 3.34Å; L63-H142 HydrophobicContact CD2-CB 4.33Å; L63-H142 PolarHBondContact O-N 2.61Å; L63-S143 PolarHBondContact O-N 2.87Å
64A90.7Very high90.6Very high3 Ų340.4 Ų40.43%0.02524%0.24CC..  trans-80.3-16.7179.400000112.5P58 A61 N62 L84 W148P58-A64 HydrophobicContact CG-CB 3.64Å; A61-A64 WeakPolarHBondContact O-CB 3.27Å; A61-A64 PolarHBondContact O-N 3.23Å; N62-A64 VanDerWaalsContact C-N 3.33Å; A64-L84 HydrophobicContact CB-CD1 4.03Å; A64-L84 HydrophobicContact CB-CD2 3.79Å; A64-W148 WeakPolarHBondContact O-CZ2 3.35Å; A64-W148 PolarHBondContact O-NE1 3.33Å
65H90.8Very high90.4Very high23 Ų2340.1 Ų40.111%0.10624%0.238CC..  trans-56.7141.6-178.8-70.9-63000112.2N62 L63 C141 H142N62-H65 PolarHBondContact O-CD2 2.84Å; N62-H65 VanDerWaalsContact O-CD2 3.27Å; L63-H65 VanDerWaalsContact C-N 3.34Å; H65-C141 WeakPolarHBondContact O-CA 3.43Å; H65-H142 PolarHBondContact O-N 3.18Å; H65-H142 VanDerWaalsContact O-N 3.07Å; H65-H142 PolarHBondContact O-ND1 3.33Å
66A90.9Very high90.5Very high3 Ų338.8 Ų38.83%0.02523%0.228CC..EExtended strand (participates in β ladder)trans-69.3145.8177.600000111.8L77 R140 V149A66-L77 HydrophobicContact CB-CB 4.23Å; A66-L77 HydrophobicContact CB-CD2 4.06Å; A66-R140 CarbonylContact C-O 3.58Å; A66-V149 HydrophobicContact CB-CG1 3.88Å; A66-V149 HydrophobicContact CB-CG2 3.96Å
67K91.1Very high90.5Very high27 Ų2738.5 Ų38.512%0.11723%0.227CC..EExtended strand (participates in β ladder)trans-121.7126.8161.3-65.7-168.3179-172.90107.4S139 R140 H142 P270 E304K67-S139 WeakPolarHBondContact O-CA 3.34Å; K67-R140 HydrophobicContact CB-CG 3.99Å; K67-R140 PolarHBondContact N-O 2.84Å; K67-R140 PolarHBondContact O-N 3.24Å; K67-H142 WeakPolarHBondContact CE-CD2 3.21Å; K67-H142 WeakPolarHBondContact CE-CE1 3.36Å; K67-H142 VanDerWaalsContact CE-CG 3.49Å; K67-H142 WeakPolarHBondContact CE-NE2 3.49Å; K67-H142 WeakPolarHBondContact CG-CE1 3.49Å; K67-P270 CarbonylContact C-O 3.4Å; K67-P270 WeakPolarHBondContact CA-O 3.33Å; K67-E304 IonicContact NZ-OE1 3.85Å; K67-E304 PolarHBondContact NZ-OE1 3.15Å; K67-E304 IonicContact NZ-OE2 3.92Å; K67-E304 PolarHBondContact NZ-OE2 2.92Å
68Q91.6Very high90.5Very high22 Ų2235.8 Ų35.810%0.10322%0.215CC..  trans-66.5140.9177.7-170.1175.8-18.200111L71 C74 L77 P270 W271Q68-L71 WeakPolarHBondContact CG-O 3.5Å; Q68-L71 PolarHBondContact NE2-O 2.86Å; Q68-C74 VanDerWaalsContact OE1-CB 3.25Å; Q68-L77 VanDerWaalsContact CA-CD1 3.45Å; Q68-L77 HydrophobicContact CB-CD1 3.47Å; Q68-L77 VanDerWaalsContact CB-CD1 3.47Å; Q68-L77 HydrophobicContact CG-CD1 3.8Å; Q68-P270 HydrophobicContact CB-CB 4.48Å; Q68-P270 PolarHBondContact N-O 3.32Å; Q68-W271 VanDerWaalsContact OE1-CD1 3.23Å; Q68-W271 VanDerWaalsContact OE1-NE1 3.14Å
69G91.8Very high90.6Very high25 Ų2535 Ų3526%0.25821%0.21SC..  trans-93.1-140.3170.500000111.9L71 C137 F138G69-L71 VanDerWaalsContact C-N 3.31Å; G69-C137 WeakPolarHBondContact CA-O 3.34Å; G69-F138 WeakPolarHBondContact CA-O 3.37Å
70L90.6Very high91Very high87 Ų8727.3 Ų27.346%0.45516%0.163SC..SBendtrans-79.8-12.3-178.9-60.5172.6000113.8L38 M132 C137L38-L70 HydrophobicContact CD1-CD1 3.82Å; L70-M132 HydrophobicContact CD1-CE 3.16Å; L70-C137 WeakPolarHBondContact CG-O 3.2Å; L70-C137 PolarHBondContact N-O 3.05Å
71L89.6Confident91.2Very high1 Ų123.7 Ų23.71%0.00514%0.144CC..SBendtrans-82137.7179.6-169.464000110.8I35 Q68 G69 D73 F138 Y163 L166 W167I35-L71 HydrophobicContact CD1-CD1 4Å; I35-L71 HydrophobicContact CG2-CD1 4.38Å; Q68-L71 WeakPolarHBondContact CG-O 3.5Å; Q68-L71 PolarHBondContact NE2-O 2.86Å; G69-L71 VanDerWaalsContact C-N 3.31Å; L71-D73 HydrophobicContact CD2-CB 3.96Å; L71-D73 HydrophobicContact CG-CB 3.97Å; L71-D73 PolarHBondContact O-N 3.43Å; L71-F138 HydrophobicContact CB-CD1 3.69Å; L71-F138 HydrophobicContact CB-CE1 4.19Å; L71-F138 HydrophobicContact CB-CG 4.36Å; L71-Y163 WeakPolarHBondContact CD1-O 3.33Å; L71-Y163 HydrophobicContact CD2-CD1 4.05Å; L71-L166 HydrophobicContact CD2-CB 4.05Å; L71-L166 HydrophobicContact CD2-CD1 4.26Å; L71-W167 HydrophobicContact CD1-CE3 4.15Å
72G88.6Confident91.6Very high15 Ų1521 Ų2116%0.15512%0.119CC..SBendtrans-78.250.3176.400000113.6A168G72-A168 PolarHBondContact O-N 2.91Å
73D90.4Very high92.1Very high0 Ų015.9 Ų15.90%09%0.091CC..  trans-110.824.5-172.174.7-35.1000113.9L71 W75 F76 L77 L166L71-D73 HydrophobicContact CD2-CB 3.96Å; L71-D73 HydrophobicContact CG-CB 3.97Å; L71-D73 PolarHBondContact O-N 3.43Å; D73-W75 PolarHBondContact O-N 2.77Å; D73-F76 HydrophobicContact CB-CB 4.47Å; D73-F76 WeakPolarHBondContact O-CB 3.36Å; D73-F76 PolarHBondContact O-N 2.81Å; D73-L77 PolarHBondContact O-N 2.96Å; D73-L166 HydrophobicContact CB-CB 4.41Å
74C91.8Very high92.3Very high13 Ų1314 Ų149%0.0888%0.081CC..Hα-helixtrans-47.3-35.517856.90000113.7Q68 F76 L77 C78 H244 A245 P270Q68-C74 VanDerWaalsContact OE1-CB 3.25Å; C74-F76 VanDerWaalsContact C-N 3.3Å; C74-F76 PolarHBondContact O-N 2.68Å; C74-L77 PolarHBondContact O-N 2.73Å; C74-C78 PolarHBondContact O-N 2.73Å; C74-C78 PolarHBondContact O-SG 2.89Å; C74-C78 VanDerWaalsContact O-SG 3.4Å; C74-H244 WeakPolarHBondContact CB-CE1 3.39Å; C74-H244 WeakPolarHBondContact CB-ND1 3.37Å; C74-H244 PolarHBondContact SG-ND1 2.86Å; C74-A245 HydrophobicContact CB-CB 4.42Å; C74-A245 PolarHBondContact SG-N 2.77Å; C74-P270 HydrophobicContact CB-CB 4.48Å; C74-P270 HydrophobicContact CB-CG 4.34Å
75W93.1Very high92.2Very high11 Ų1119 Ų194%0.04210%0.103CC..Hα-helixtrans-56.3-40.3175.968.3-82.9000113.5D73 Y156 L166 G169 V171 E173 A174D73-W75 PolarHBondContact O-N 2.77Å; W75-Y156 AromaticContact CH2-CE1 3.55Å; W75-Y156 HydrophobicContact CH2-CE1 3.55Å; W75-Y156 AromaticContact CH2-CZ 3.9Å; W75-Y156 VanDerWaalsContact CH2-OH 3.31Å; W75-Y156 WeakPolarHBondContact CH2-OH 3.42Å; W75-Y156 HydrophobicContact CZ2-CE1 4.01Å; W75-Y156 HydrophobicContact CZ3-CE1 4.24Å; W75-Y156 WeakPolarHBondContact CZ3-OH 3.48Å; W75-L166 PolarHBondContact NE1-O 2.96Å; W75-G169 VanDerWaalsContact CG-C 3.43Å; W75-G169 VanDerWaalsContact NE1-N 3.13Å; W75-V171 HydrophobicContact CB-CG2 4Å; W75-E173 HydrophobicContact CZ3-CB 4.09Å; W75-A174 HydrophobicContact CE3-CB 3.55Å; W75-A174 HydrophobicContact CZ3-CB 3.57Å
76F96Very high92.3Very high0 Ų019.2 Ų19.20%010%0.104CC..Hα-helixtrans-74.1-42.2177.4171.4-108.4000110.8D73 C74 C78 A79 C80 L152 E153 Y156 A174 L178D73-F76 HydrophobicContact CB-CB 4.47Å; D73-F76 WeakPolarHBondContact O-CB 3.36Å; D73-F76 PolarHBondContact O-N 2.81Å; C74-F76 VanDerWaalsContact C-N 3.3Å; C74-F76 PolarHBondContact O-N 2.68Å; F76-C78 VanDerWaalsContact C-N 3.31Å; F76-C78 PolarHBondContact O-N 2.79Å; F76-A79 WeakPolarHBondContact O-CA 3.36Å; F76-A79 WeakPolarHBondContact O-CB 3.42Å; F76-A79 PolarHBondContact O-N 2.77Å; F76-C80 VanDerWaalsContact CE1-SG 3.54Å; F76-C80 PolarHBondContact O-N 3.43Å; F76-C80 PolarHBondContact O-SG 2.68Å; F76-C80 VanDerWaalsContact O-SG 3.4Å; F76-L152 HydrophobicContact CZ-CD2 4.09Å; F76-L152 HydrophobicContact CZ-CG 3.95Å; F76-E153 HydrophobicContact CE1-CB 3.95Å; F76-E153 HydrophobicContact CE1-CG 4.31Å; F76-Y156 AromaticContact CD2-CD1 3.65Å; F76-Y156 HydrophobicContact CD2-CD1 3.65Å; F76-Y156 AromaticContact CD2-CE1 3.68Å; F76-Y156 HydrophobicContact CD2-CE1 3.68Å; F76-Y156 HydrophobicContact CD2-CG 4.08Å; F76-Y156 AromaticContact CE2-CD1 3.67Å; F76-Y156 HydrophobicContact CE2-CD1 3.67Å; F76-Y156 AromaticContact CE2-CD2 3.97Å; F76-Y156 HydrophobicContact CE2-CD2 3.97Å; F76-Y156 HydrophobicContact CE2-CE1 4.08Å; F76-Y156 HydrophobicContact CE2-CE2 4.37Å; F76-Y156 AromaticContact CE2-CG 3.61Å; F76-Y156 HydrophobicContact CE2-CG 3.61Å; F76-Y156 HydrophobicContact CG-CD1 4.22Å; F76-Y156 HydrophobicContact CG-CE1 4.35Å; F76-Y156 HydrophobicContact CZ-CD1 4.26Å; F76-Y156 HydrophobicContact CZ-CG 4.11Å; F76-A174 HydrophobicContact CB-CB 4.44Å; F76-A174 HydrophobicContact CD2-CB 4.11Å; F76-L178 HydrophobicContact CD2-CD1 4.49Å; F76-L178 HydrophobicContact CE2-CD1 4.08Å; F76-L178 HydrophobicContact CE2-CD2 4.31Å; F76-L178 HydrophobicContact CE2-CG 4.47Å
77L94.9Very high92.3Very high0 Ų024.5 Ų24.50%013%0.129CC..Hα-helixtrans-66.6-30.6179.5-54.4-178.7000113.4A66 Q68 D73 C74 A79 C80 T81 S139 V149 P270A66-L77 HydrophobicContact CB-CB 4.23Å; A66-L77 HydrophobicContact CB-CD2 4.06Å; Q68-L77 VanDerWaalsContact CA-CD1 3.45Å; Q68-L77 HydrophobicContact CB-CD1 3.47Å; Q68-L77 VanDerWaalsContact CB-CD1 3.47Å; Q68-L77 HydrophobicContact CG-CD1 3.8Å; D73-L77 PolarHBondContact O-N 2.96Å; C74-L77 PolarHBondContact O-N 2.73Å; L77-A79 VanDerWaalsContact C-N 3.31Å; L77-C80 PolarHBondContact O-N 3.38Å; L77-T81 PolarHBondContact O-N 2.83Å; L77-T81 PolarHBondContact O-OG1 3.48Å; L77-S139 WeakPolarHBondContact CD1-OG 3.3Å; L77-S139 VanDerWaalsContact CD2-OG 3.23Å; L77-S139 WeakPolarHBondContact CD2-OG 3.42Å; L77-V149 HydrophobicContact CD2-CG1 3.92Å; L77-P270 HydrophobicContact CB-CB 4.22Å; L77-P270 HydrophobicContact CD1-CB 4.35Å
78C94.1Very high92.4Very high4 Ų426.1 Ų26.13%0.02714%0.137CC..Hα-helixtrans-59.5-42.4168.3-76.40000111.6C74 F76 T81 F82 V171 T247C74-C78 PolarHBondContact O-N 2.73Å; C74-C78 PolarHBondContact O-SG 2.89Å; C74-C78 VanDerWaalsContact O-SG 3.4Å; F76-C78 VanDerWaalsContact C-N 3.31Å; F76-C78 PolarHBondContact O-N 2.79Å; C78-T81 WeakPolarHBondContact O-CB 3.32Å; C78-T81 PolarHBondContact O-N 3.05Å; C78-F82 PolarHBondContact O-N 2.97Å; C78-V171 HydrophobicContact CB-CG1 4.04Å; C78-V171 HydrophobicContact CB-CG2 4.13Å; C78-T247 WeakPolarHBondContact CA-OG1 3.48Å; C78-T247 PolarHBondContact SG-OG1 3.41Å
79A95.7Very high92.6Very high1 Ų125 Ų251%0.00813%0.132CC..Hα-helixtrans-70.2-37.5175.900000112.2F76 L77 T81 F82 L83 A174 L175 L178F76-A79 WeakPolarHBondContact O-CA 3.36Å; F76-A79 WeakPolarHBondContact O-CB 3.42Å; F76-A79 PolarHBondContact O-N 2.77Å; L77-A79 VanDerWaalsContact C-N 3.31Å; A79-T81 VanDerWaalsContact C-N 3.26Å; A79-T81 PolarHBondContact O-N 3.08Å; A79-F82 WeakPolarHBondContact O-CB 3.36Å; A79-F82 PolarHBondContact O-N 3.4Å; A79-F82 VanDerWaalsContact O-N 3.1Å; A79-L83 PolarHBondContact O-N 2.85Å; A79-A174 HydrophobicContact CB-CB 3.54Å; A79-L175 HydrophobicContact CB-CD2 3.89Å; A79-L175 HydrophobicContact CB-CG 4.07Å; A79-L178 HydrophobicContact CB-CD1 3.87Å
80C95.8Very high92.8Very high0 Ų024.4 Ų24.40%012%0.122CC..Hα-helixtrans-59.2-36.8172.1-650000112.3F76 L77 F82 L83 L84 W148F76-C80 VanDerWaalsContact CE1-SG 3.54Å; F76-C80 PolarHBondContact O-N 3.43Å; F76-C80 PolarHBondContact O-SG 2.68Å; F76-C80 VanDerWaalsContact O-SG 3.4Å; L77-C80 PolarHBondContact O-N 3.38Å; C80-F82 VanDerWaalsContact C-N 3.28Å; C80-F82 PolarHBondContact O-N 3.32Å; C80-L83 WeakPolarHBondContact O-CB 3.41Å; C80-L83 PolarHBondContact O-N 2.88Å; C80-L84 PolarHBondContact O-N 3.03Å; C80-L84 VanDerWaalsContact O-N 3.16Å; C80-W148 HydrophobicContact CB-CH2 3.86Å; C80-W148 HydrophobicContact CB-CZ3 4.36Å
81T92.7Very high93Very high4 Ų423.6 Ų23.63%0.02512%0.118CC..Hα-helixtrans-62.8-37.1175.9-60.40000111.6L77 C78 A79 T247 M249L77-T81 PolarHBondContact O-N 2.83Å; L77-T81 PolarHBondContact O-OG1 3.48Å; C78-T81 WeakPolarHBondContact O-CB 3.32Å; C78-T81 PolarHBondContact O-N 3.05Å; A79-T81 VanDerWaalsContact C-N 3.26Å; A79-T81 PolarHBondContact O-N 3.08Å; T81-T247 HydrophobicContact CG2-CG2 3.96Å; T81-M249 HydrophobicContact CG2-CE 3.95Å; T81-M249 HydrophobicContact CG2-SD 3.69Å
82F91.8Very high93.3Very high16 Ų1626.6 Ų26.67%0.0713%0.131CC..Hα-helixtrans-69.8-40.2173.1178.4-107.2000112.4C78 A79 C80 L84 K85 N86 L89 L175 T179 E223 A225C78-F82 PolarHBondContact O-N 2.97Å; A79-F82 WeakPolarHBondContact O-CB 3.36Å; A79-F82 PolarHBondContact O-N 3.4Å; A79-F82 VanDerWaalsContact O-N 3.1Å; C80-F82 VanDerWaalsContact C-N 3.28Å; C80-F82 PolarHBondContact O-N 3.32Å; F82-L84 PolarHBondContact O-N 2.86Å; F82-K85 WeakPolarHBondContact O-CB 3.39Å; F82-K85 PolarHBondContact O-N 2.98Å; F82-N86 PolarHBondContact O-N 3.05Å; F82-L89 HydrophobicContact CE1-CD1 4.02Å; F82-L175 HydrophobicContact CB-CD2 4.15Å; F82-L175 HydrophobicContact CD1-CD2 4.07Å; F82-L175 HydrophobicContact CG-CD2 4.3Å; F82-T179 HydrophobicContact CD1-CG2 4.06Å; F82-T179 HydrophobicContact CE1-CG2 3.89Å; F82-E223 WeakPolarHBondContact CE2-O 3.37Å; F82-A225 HydrophobicContact CB-CB 4.03Å; F82-A225 HydrophobicContact CD1-CB 3.96Å; F82-A225 HydrophobicContact CD2-CB 3.4Å; F82-A225 VanDerWaalsContact CD2-CB 3.4Å; F82-A225 HydrophobicContact CE1-CB 4.26Å; F82-A225 HydrophobicContact CE2-CB 3.74Å; F82-A225 HydrophobicContact CG-CB 3.51Å; F82-A225 HydrophobicContact CZ-CB 4.15Å
83L93.6Very high93.8Very high2 Ų225.9 Ų25.91%0.0112%0.124CC..Hα-helixtrans-56-40177.8-172.164.1000111.9A79 C80 K85 N86 L89 L90 V93 F94 W148 L152A79-L83 PolarHBondContact O-N 2.85Å; C80-L83 WeakPolarHBondContact O-CB 3.41Å; C80-L83 PolarHBondContact O-N 2.88Å; L83-K85 PolarHBondContact O-N 2.86Å; L83-N86 PolarHBondContact O-N 2.73Å; L83-L89 VanDerWaalsContact CD1-C 3.48Å; L83-L89 HydrophobicContact CD1-CB 3.68Å; L83-L90 HydrophobicContact CD2-CD1 3.98Å; L83-L90 HydrophobicContact CG-CB 4.45Å; L83-L90 HydrophobicContact CG-CD1 3.78Å; L83-V93 HydrophobicContact CD1-CB 4.32Å; L83-V93 HydrophobicContact CD1-CG2 3.83Å; L83-V93 HydrophobicContact CD2-CB 4.02Å; L83-V93 HydrophobicContact CD2-CG1 3.94Å; L83-V93 HydrophobicContact CD2-CG2 4.1Å; L83-F94 HydrophobicContact CD2-CE2 4.21Å; L83-W148 HydrophobicContact CD2-CZ3 4.3Å; L83-L152 HydrophobicContact CD2-CD2 4.07Å
84L91.7Very high94.1Very high36 Ų3626.3 Ų26.319%0.18813%0.126CC..Hα-helixtrans-61.5-28174.7-76.2177.8000114.4A64 C80 F82 N86 W148A64-L84 HydrophobicContact CB-CD1 4.03Å; A64-L84 HydrophobicContact CB-CD2 3.79Å; C80-L84 PolarHBondContact O-N 3.03Å; C80-L84 VanDerWaalsContact O-N 3.16Å; F82-L84 PolarHBondContact O-N 2.86Å; L84-N86 VanDerWaalsContact C-N 3.34Å; L84-W148 HydrophobicContact CD1-CH2 4.2Å; L84-W148 HydrophobicContact CD1-CZ2 3.6Å; L84-W148 HydrophobicContact CD2-CH2 3.89Å; L84-W148 HydrophobicContact CD2-CZ2 3.45Å; L84-W148 VanDerWaalsContact CD2-CZ2 3.45Å; L84-W148 HydrophobicContact CG-CH2 3.68Å; L84-W148 HydrophobicContact CG-CZ2 3.46Å; L84-W148 VanDerWaalsContact CG-CZ2 3.46Å
85K89.6Confident94.2Very high110 Ų11026.8 Ų26.848%0.47813%0.129SC..Hα-helixtrans-80.2-16.4179.2-67.8-175.3170.5-170.60112.5F82 L83 M249F82-K85 WeakPolarHBondContact O-CB 3.39Å; F82-K85 PolarHBondContact O-N 2.98Å; L83-K85 PolarHBondContact O-N 2.86Å; K85-M249 PolarHBondContact NZ-O 2.88Å
86N92.3Very high94.1Very high26 Ų2631.2 Ų31.214%0.13916%0.159CC..  trans-120.795.2-176.2-169-42.4000111.3F82 L83 L84 H88 L89 L90 I327F82-N86 PolarHBondContact O-N 3.05Å; L83-N86 PolarHBondContact O-N 2.73Å; L84-N86 VanDerWaalsContact C-N 3.34Å; N86-H88 VanDerWaalsContact C-N 3.26Å; N86-H88 PolarHBondContact O-N 3.36Å; N86-H88 WeakPolarHBondContact OD1-CB 3.32Å; N86-H88 PolarHBondContact OD1-N 3.31Å; N86-L89 HydrophobicContact CB-CB 4.19Å; N86-L89 HydrophobicContact CB-CD1 4.01Å; N86-L89 HydrophobicContact CB-CG 4.25Å; N86-L89 PolarHBondContact O-N 3.34Å; N86-L89 VanDerWaalsContact O-N 3.14Å; N86-L89 PolarHBondContact OD1-N 3.49Å; N86-L89 VanDerWaalsContact OD1-N 3.11Å; N86-L90 PolarHBondContact O-N 3.18Å; N86-I327 PolarHBondContact ND2-O 3.23Å
87Q92Very high93.8Very high114 Ų11433.8 Ų33.853%0.53319%0.185SC..Hα-helixtrans-57.5-36.4-178.3-169.864.147.800113.2L90 D91Q87-L90 PolarHBondContact O-N 3.02Å; Q87-D91 PolarHBondContact NE2-OD1 3.19Å; Q87-D91 WeakPolarHBondContact O-CB 3.47Å; Q87-D91 VanDerWaalsContact O-CG 3.24Å; Q87-D91 PolarHBondContact O-N 2.81Å
88H93.6Very high93.7Very high61 Ų6134.7 Ų34.728%0.28219%0.19SC..Hα-helixtrans-62.5-45.3178.5171.479.1000111.4N86 K92 K329N86-H88 VanDerWaalsContact C-N 3.26Å; N86-H88 PolarHBondContact O-N 3.36Å; N86-H88 WeakPolarHBondContact OD1-CB 3.32Å; N86-H88 PolarHBondContact OD1-N 3.31Å; H88-K92 WeakPolarHBondContact O-CB 3.35Å; H88-K92 PolarHBondContact O-N 2.83Å; H88-K92 VanDerWaalsContact O-N 3.08Å; H88-K329 PolarHBondContact CE1-O 3.06Å; H88-K329 PolarHBondContact ND1-O 3.23Å
89L95.6Very high93.4Very high0 Ų035.4 Ų35.40%020%0.195CC..Hα-helixtrans-70.5-37.1176.4-64175.2000111.6F82 L83 N86 K92 V93 T179 I327F82-L89 HydrophobicContact CE1-CD1 4.02Å; L83-L89 VanDerWaalsContact CD1-C 3.48Å; L83-L89 HydrophobicContact CD1-CB 3.68Å; N86-L89 HydrophobicContact CB-CB 4.19Å; N86-L89 HydrophobicContact CB-CD1 4.01Å; N86-L89 HydrophobicContact CB-CG 4.25Å; N86-L89 PolarHBondContact O-N 3.34Å; N86-L89 VanDerWaalsContact O-N 3.14Å; N86-L89 PolarHBondContact OD1-N 3.49Å; N86-L89 VanDerWaalsContact OD1-N 3.11Å; L89-K92 WeakPolarHBondContact O-CB 3.37Å; L89-K92 PolarHBondContact O-N 2.78Å; L89-K92 VanDerWaalsContact O-N 3.16Å; L89-V93 WeakPolarHBondContact O-CG2 3.34Å; L89-V93 PolarHBondContact O-N 2.84Å; L89-T179 HydrophobicContact CD1-CG2 3.84Å; L89-I327 HydrophobicContact CD1-CB 4.18Å; L89-I327 HydrophobicContact CD1-CD1 4.28Å; L89-I327 HydrophobicContact CD2-CB 4.35Å; L89-I327 HydrophobicContact CD2-CD1 4.03Å; L89-I327 HydrophobicContact CD2-CG2 4.14Å
90L95.2Very high93.1Very high12 Ų1239.4 Ų39.46%0.06321%0.213CC..Hα-helixtrans-59.8-48.6175.3-170.468.6000110.9F57 L83 N86 Q87 K92 V93 F94F57-L90 HydrophobicContact CE1-CD1 3.94Å; F57-L90 HydrophobicContact CE1-CD2 4.07Å; F57-L90 HydrophobicContact CE1-CG 4.4Å; F57-L90 HydrophobicContact CZ-CD1 3.96Å; F57-L90 HydrophobicContact CZ-CD2 4.28Å; F57-L90 HydrophobicContact CZ-CG 4.27Å; L83-L90 HydrophobicContact CD2-CD1 3.98Å; L83-L90 HydrophobicContact CG-CB 4.45Å; L83-L90 HydrophobicContact CG-CD1 3.78Å; N86-L90 PolarHBondContact O-N 3.18Å; Q87-L90 PolarHBondContact O-N 3.02Å; L90-K92 PolarHBondContact O-N 2.84Å; L90-V93 PolarHBondContact O-N 2.81Å; L90-F94 HydrophobicContact CD1-CD2 3.79Å; L90-F94 HydrophobicContact CD1-CE2 4.05Å; L90-F94 HydrophobicContact CG-CD2 4.45Å; L90-F94 WeakPolarHBondContact O-CA 3.2Å; L90-F94 VanDerWaalsContact O-CB 3.3Å; L90-F94 WeakPolarHBondContact O-CB 3.35Å; L90-F94 PolarHBondContact O-N 2.83Å
91D95.3Very high93Very high70 Ų7040.5 Ų40.537%0.37422%0.217SC..Hα-helixtrans-65.6-26.5176.8-67.5-19.4000112.4Q87 F94 P96Q87-D91 PolarHBondContact NE2-OD1 3.19Å; Q87-D91 WeakPolarHBondContact O-CB 3.47Å; Q87-D91 VanDerWaalsContact O-CG 3.24Å; Q87-D91 PolarHBondContact O-N 2.81Å; D91-F94 CarbonylContact C-O 3.5Å; D91-F94 CarbonylContact O-C 3.6Å; D91-F94 VanDerWaalsContact O-C 3.24Å; D91-P96 HydrophobicContact CB-CG 4.35Å
92K95.9Very high92.7Very high63 Ų6344.2 Ų44.227%0.27426%0.256SS..Hα-helixtrans-73.2-49.2174.7-165.1173.9-165.9178.60111.2H88 L89 L90 F94 L113 W120H88-K92 WeakPolarHBondContact O-CB 3.35Å; H88-K92 PolarHBondContact O-N 2.83Å; H88-K92 VanDerWaalsContact O-N 3.08Å; L89-K92 WeakPolarHBondContact O-CB 3.37Å; L89-K92 PolarHBondContact O-N 2.78Å; L89-K92 VanDerWaalsContact O-N 3.16Å; L90-K92 PolarHBondContact O-N 2.84Å; K92-F94 VanDerWaalsContact C-N 3.34Å; K92-L113 WeakPolarHBondContact O-CB 3.26Å; K92-L113 WeakPolarHBondContact O-CD1 3.4Å; K92-W120 HydrophobicContact CD-CD2 4.33Å; K92-W120 HydrophobicContact CD-CH2 3.83Å; K92-W120 HydrophobicContact CD-CZ2 3.54Å; K92-W120 HydrophobicContact CD-CZ3 4.35Å; K92-W120 VanDerWaalsContact CE-CZ2 3.42Å; K92-W120 VanDerWaalsContact CE-NE1 3.28Å; K92-W120 HydrophobicContact CG-CD2 4.48Å; K92-W120 HydrophobicContact CG-CE3 4.44Å; K92-W120 HydrophobicContact CG-CH2 4.26Å; K92-W120 HydrophobicContact CG-CZ2 4.34Å; K92-W120 HydrophobicContact CG-CZ3 4.32Å; K92-W120 VanDerWaalsContact NZ-NE1 3.18Å
93V97.8Very high92.6Very high0 Ų045.5 Ų45.50%027%0.267CS..Hα-helixtrans-68.7-35.8177.9174.30000111.2L83 L89 L90 P95 F112 L113 W120 L152 L178L83-V93 HydrophobicContact CD1-CB 4.32Å; L83-V93 HydrophobicContact CD1-CG2 3.83Å; L83-V93 HydrophobicContact CD2-CB 4.02Å; L83-V93 HydrophobicContact CD2-CG1 3.94Å; L83-V93 HydrophobicContact CD2-CG2 4.1Å; L89-V93 WeakPolarHBondContact O-CG2 3.34Å; L89-V93 PolarHBondContact O-N 2.84Å; L90-V93 PolarHBondContact O-N 2.81Å; V93-P95 VanDerWaalsContact O-CD 3.32Å; V93-P95 WeakPolarHBondContact O-CD 3.3Å; V93-F112 CarbonylContact O-C 3.57Å; V93-F112 VanDerWaalsContact O-CA 3.25Å; V93-F112 WeakPolarHBondContact O-CA 3.33Å; V93-L113 WeakPolarHBondContact CA-O 3.29Å; V93-L113 PolarHBondContact O-N 2.76Å; V93-W120 HydrophobicContact CG2-CZ3 4.17Å; V93-L152 HydrophobicContact CG1-CD1 3.53Å; V93-L152 HydrophobicContact CG1-CD2 4.45Å; V93-L178 HydrophobicContact CG1-CD2 4.41Å; V93-L178 VanDerWaalsContact CG2-O 3.31Å; V93-L178 WeakPolarHBondContact CG2-O 3.24Å
94F96.8Very high92.4Very high9 Ų950.5 Ų50.54%0.03930%0.302CS..SBendtrans-112.688.4175.6-70-99.5000110.3L56 F57 L83 L90 D91 K92 F112 W148 L152L56-F94 HydrophobicContact CD2-CD1 4.25Å; F57-F94 AromaticContact CE2-CD1 3.95Å; F57-F94 HydrophobicContact CE2-CD1 3.95Å; F57-F94 HydrophobicContact CE2-CE1 4.3Å; F57-F94 HydrophobicContact CE2-CG 4.19Å; F57-F94 HydrophobicContact CZ-CB 4.47Å; F57-F94 AromaticContact CZ-CD1 3.79Å; F57-F94 HydrophobicContact CZ-CD1 3.79Å; F57-F94 AromaticContact CZ-CD2 3.97Å; F57-F94 HydrophobicContact CZ-CD2 3.97Å; F57-F94 AromaticContact CZ-CE1 3.89Å; F57-F94 HydrophobicContact CZ-CE1 3.89Å; F57-F94 HydrophobicContact CZ-CE2 4.12Å; F57-F94 AromaticContact CZ-CG 3.82Å; F57-F94 HydrophobicContact CZ-CG 3.82Å; F57-F94 HydrophobicContact CZ-CZ 4.09Å; L83-F94 HydrophobicContact CD2-CE2 4.21Å; L90-F94 HydrophobicContact CD1-CD2 3.79Å; L90-F94 HydrophobicContact CD1-CE2 4.05Å; L90-F94 HydrophobicContact CG-CD2 4.45Å; L90-F94 WeakPolarHBondContact O-CA 3.2Å; L90-F94 VanDerWaalsContact O-CB 3.3Å; L90-F94 WeakPolarHBondContact O-CB 3.35Å; L90-F94 PolarHBondContact O-N 2.83Å; D91-F94 CarbonylContact C-O 3.5Å; D91-F94 CarbonylContact O-C 3.6Å; D91-F94 VanDerWaalsContact O-C 3.24Å; K92-F94 VanDerWaalsContact C-N 3.34Å; F94-F112 HydrophobicContact CD1-CD1 4.26Å; F94-F112 AromaticContact CD1-CE1 3.86Å; F94-F112 HydrophobicContact CD1-CE1 3.86Å; F94-F112 AromaticContact CE1-CD1 3.96Å; F94-F112 HydrophobicContact CE1-CD1 3.96Å; F94-F112 AromaticContact CE1-CE1 3.25Å; F94-F112 HydrophobicContact CE1-CE1 3.25Å; F94-F112 HydrophobicContact CE1-CZ 4.11Å; F94-F112 HydrophobicContact CE2-CE1 4.45Å; F94-F112 HydrophobicContact CZ-CD1 4.06Å; F94-F112 AromaticContact CZ-CE1 3.56Å; F94-F112 HydrophobicContact CZ-CE1 3.56Å; F94-W148 HydrophobicContact CE1-CB 3.93Å; F94-W148 AromaticContact CE2-CE3 3.68Å; F94-W148 HydrophobicContact CE2-CE3 3.68Å; F94-W148 HydrophobicContact CE2-CZ3 4.17Å; F94-W148 HydrophobicContact CZ-CB 3.98Å; F94-W148 HydrophobicContact CZ-CD2 4.38Å; F94-W148 AromaticContact CZ-CE3 3.53Å; F94-W148 HydrophobicContact CZ-CE3 3.53Å; F94-W148 HydrophobicContact CZ-CZ3 4.37Å; F94-L152 HydrophobicContact CE2-CD1 4.23Å; F94-L152 HydrophobicContact CE2-CD2 4.07Å; F94-L152 HydrophobicContact CE2-CG 4.49Å; F94-L152 HydrophobicContact CZ-CB 3.91Å; F94-L152 HydrophobicContact CZ-CD1 4.26Å; F94-L152 HydrophobicContact CZ-CD2 4.26Å; F94-L152 HydrophobicContact CZ-CG 4.36Å
95P94.9Very high92.3Very high24 Ų2456.5 Ų56.516%0.15632%0.322CS..  trans-49.8129178.2-29.635.5000111.9V93 Q98 L113V93-P95 VanDerWaalsContact O-CD 3.32Å; V93-P95 WeakPolarHBondContact O-CD 3.3Å; P95-Q98 WeakPolarHBondContact O-CG 3.07Å; P95-L113 HydrophobicContact CG-CD1 4.35Å; P95-L113 HydrophobicContact CG-CG 4.02Å
96P91.5Very high92.6Very high103 Ų10352.2 Ų52.267%0.66930%0.303SS*.THydrogen-bonded Turntrans-57.3151.6-179.4-27.534.9000112.8D91D91-P96 HydrophobicContact CB-CG 4.35Å
97G89.1Confident92.7Very high54 Ų5456.3 Ų56.356%0.55732%0.317SS*.THydrogen-bonded Turntrans86.412.3176.100000115.3
98Q91.7Very high92.8Very high19 Ų1950.9 Ų50.99%0.08929%0.291CS..PPolyproline II helixtrans-56.9138.9168.6-55-143.654.400110.7L56 P95 F110 R111L56-Q98 HydrophobicContact CD2-CB 4.34Å; P95-Q98 WeakPolarHBondContact O-CG 3.07Å; Q98-F110 HydrophobicContact CB-CD1 4.45Å; Q98-F110 VanDerWaalsContact OE1-CA 3.29Å; Q98-R111 PolarHBondContact NE2-O 2.95Å; Q98-R111 PolarHBondContact OE1-O 2.89Å
99P88.3Confident92.9Very high20 Ų2049.3 Ų49.313%0.1329%0.287CS..PPolyproline II helixtrans-67.3140.4-17828.9-34.2000111R105P99-R105 HydrophobicContact CB-CB 4.16Å
100Q90.1Very high93Very high85 Ų8549.3 Ų49.340%0.39729%0.287SS..PPolyproline II helixtrans-85.7151.6168-63-61.1-46.100109.9S103Q100-S103 WeakPolarHBondContact O-CB 3.46Å; Q100-S103 PolarHBondContact O-N 2.82Å; Q100-S103 VanDerWaalsContact O-N 3.1Å
101W93.1Very high93.1Very high23 Ų2353.7 Ų53.79%0.08730%0.303CS..THydrogen-bonded Turntrans-56.7140.4169.8-66.3-83.7000110.8P47 Q48 P54 L56 S103 Y106 F110 D127 F147 L151P47-W101 HydrophobicContact CB-CD2 4.37Å; P47-W101 HydrophobicContact CB-CZ2 3.92Å; P47-W101 HydrophobicContact CG-CH2 4.4Å; P47-W101 HydrophobicContact CG-CZ2 3.52Å; Q48-W101 VanDerWaalsContact OE1-CD1 3.29Å; P54-W101 HydrophobicContact CB-CB 4.41Å; P54-W101 HydrophobicContact CB-CD2 3.83Å; P54-W101 HydrophobicContact CB-CE3 4Å; P54-W101 HydrophobicContact CB-CG 4.02Å; P54-W101 HydrophobicContact CG-CB 3.64Å; P54-W101 HydrophobicContact CG-CD2 3.95Å; P54-W101 HydrophobicContact CG-CE3 4.46Å; P54-W101 HydrophobicContact CG-CG 3.57Å; L56-W101 HydrophobicContact CB-CZ3 4.07Å; L56-W101 HydrophobicContact CD1-CH2 4.17Å; L56-W101 HydrophobicContact CD1-CZ3 4.44Å; W101-S103 VanDerWaalsContact C-N 3.25Å; W101-S103 PolarHBondContact O-N 2.77Å; W101-Y106 AromaticContact CD1-CD2 3.98Å; W101-Y106 AromaticContact CD1-CE2 3.35Å; W101-Y106 AromaticContact CD1-CZ 3.68Å; W101-Y106 HydrophobicContact CG-CD2 4.47Å; W101-Y106 HydrophobicContact CG-CE2 4.21Å; W101-Y106 AromaticContact NE1-CE2 3.43Å; W101-Y106 AromaticContact NE1-CZ 3.86Å; W101-F110 HydrophobicContact CD2-CZ 4.45Å; W101-F110 AromaticContact CE2-CZ 3.83Å; W101-F110 AromaticContact CH2-CE1 4Å; W101-F110 HydrophobicContact CH2-CE1 4Å; W101-F110 HydrophobicContact CH2-CE2 4.21Å; W101-F110 AromaticContact CH2-CZ 3.53Å; W101-F110 HydrophobicContact CH2-CZ 3.53Å; W101-F110 HydrophobicContact CZ2-CE1 4.24Å; W101-F110 AromaticContact CZ2-CE2 3.66Å; W101-F110 HydrophobicContact CZ2-CE2 3.66Å; W101-F110 AromaticContact CZ2-CZ 3.34Å; W101-F110 HydrophobicContact CZ2-CZ 3.34Å; W101-F110 HydrophobicContact CZ3-CE1 4.44Å; W101-F110 HydrophobicContact CZ3-CZ 4.13Å; W101-D127 HydrophobicContact CZ2-CB 4.37Å; W101-D127 PolarHBondContact NE1-OD2 3.13Å; W101-F147 HydrophobicContact CH2-CB 4.02Å; W101-L151 HydrophobicContact CH2-CD1 3.76Å; W101-L151 HydrophobicContact CZ2-CD1 4.04Å
102G87.1Confident93.3Very high81 Ų8150.4 Ų50.484%0.83529%0.285SS*.THydrogen-bonded Turntrans81.1-8.5-173.900000115.1
103S89.9Confident93.4Very high44 Ų4449.4 Ų49.431%0.30828%0.283SS..SBendtrans-74.5147.3172-176.80000111.9Q100 W101 R105 Y106Q100-S103 WeakPolarHBondContact O-CB 3.46Å; Q100-S103 PolarHBondContact O-N 2.82Å; Q100-S103 VanDerWaalsContact O-N 3.1Å; W101-S103 VanDerWaalsContact C-N 3.25Å; W101-S103 PolarHBondContact O-N 2.77Å; S103-R105 PolarHBondContact O-N 2.78Å; S103-R105 VanDerWaalsContact O-N 3.12Å; S103-R105 PolarHBondContact OG-N 3.28Å; S103-Y106 VanDerWaalsContact O-CB 3.24Å; S103-Y106 WeakPolarHBondContact O-CB 3.35Å; S103-Y106 PolarHBondContact O-N 3.13Å
104S88.6Confident93.4Very high107 Ų10749.4 Ų49.475%0.74828%0.283SS*.THydrogen-bonded Turntrans-60.8-19.3171.260.30000113.8R107S104-R107 PolarHBondContact O-NH1 2.75Å; S104-R107 PolarHBondContact O-NH2 2.79Å
105R90.6Very high93.4Very high161 Ų16149.4 Ų49.461%0.60828%0.282SS*.THydrogen-bonded Turntrans-86.6-7.6175.5-61-166.6-61.61782.4113.8P99 S103 R107P99-R105 HydrophobicContact CB-CB 4.16Å; S103-R105 PolarHBondContact O-N 2.78Å; S103-R105 VanDerWaalsContact O-N 3.12Å; S103-R105 PolarHBondContact OG-N 3.28Å; R105-R107 PolarHBondContact O-N 2.98Å
106Y94.6Very high93.1Very high20 Ų2049.7 Ų49.78%0.07828%0.282CS..  trans-66127.3179.8173.3-99.5000110.9L14 Q48 W101 S103 G108 F110 D127L14-Y106 HydrophobicContact CD1-CE1 4.22Å; L14-Y106 HydrophobicContact CD2-CD1 4Å; L14-Y106 HydrophobicContact CD2-CE1 3.51Å; Q48-Y106 VanDerWaalsContact NE2-CZ 3.3Å; Q48-Y106 PolarHBondContact NE2-OH 3.39Å; Q48-Y106 PolarHBondContact OE1-OH 3.14Å; W101-Y106 AromaticContact CD1-CD2 3.98Å; W101-Y106 AromaticContact CD1-CE2 3.35Å; W101-Y106 AromaticContact CD1-CZ 3.68Å; W101-Y106 HydrophobicContact CG-CD2 4.47Å; W101-Y106 HydrophobicContact CG-CE2 4.21Å; W101-Y106 AromaticContact NE1-CE2 3.43Å; W101-Y106 AromaticContact NE1-CZ 3.86Å; S103-Y106 VanDerWaalsContact O-CB 3.24Å; S103-Y106 WeakPolarHBondContact O-CB 3.35Å; S103-Y106 PolarHBondContact O-N 3.13Å; Y106-G108 VanDerWaalsContact CZ-CA 3.47Å; Y106-F110 HydrophobicContact CE2-CE2 4.31Å; Y106-F110 HydrophobicContact CE2-CZ 4.49Å; Y106-D127 VanDerWaalsContact CE2-OD2 3.25Å; Y106-D127 WeakPolarHBondContact CE2-OD2 3.07Å; Y106-D127 VanDerWaalsContact CZ-OD2 3.3Å; Y106-D127 VanDerWaalsContact OH-CG 3.31Å; Y106-D127 PolarHBondContact OH-OD1 3.25Å; Y106-D127 PolarHBondContact OH-OD2 3.07Å
107R94.3Very high92.7Very high112 Ų11248.4 Ų48.442%0.42327%0.267SS..  trans-131.614.5176.9-64.5-65.6179.7-79.5-2.4112.2F15 S104 R105 S109F15-R107 WeakPolarHBondContact CB-O 3.23Å; F15-R107 PolarHBondContact N-O 2.91Å; S104-R107 PolarHBondContact O-NH1 2.75Å; S104-R107 PolarHBondContact O-NH2 2.79Å; R105-R107 PolarHBondContact O-N 2.98Å; R107-S109 VanDerWaalsContact C-N 3.26Å; R107-S109 PolarHBondContact O-N 2.81Å
108G95.3Very high92.7Very high0 Ų046.2 Ų46.20%024%0.244CC..SBendtrans6428.1-177.600000114.2R46 Y106 D126 D127R46-G108 PolarHBondContact NH1-O 2.78Å; Y106-G108 VanDerWaalsContact CZ-CA 3.47Å; G108-D126 WeakPolarHBondContact O-CA 3.25Å; G108-D126 WeakPolarHBondContact O-CB 3.27Å; G108-D127 PolarHBondContact O-N 3.39Å
109S95.6Very high92.7Very high28 Ų2851.2 Ų51.220%0.19627%0.267CS..EExtended strand (participates in β ladder)trans-129.5131.4-177.1-178.20000110.1R107 T124R107-S109 VanDerWaalsContact C-N 3.26Å; R107-S109 PolarHBondContact O-N 2.81Å; S109-T124 VanDerWaalsContact OG-CG2 3.3Å; S109-T124 WeakPolarHBondContact OG-CG2 3.39Å
110F97.3Very high93Very high0 Ų053.7 Ų53.70%027%0.274CS..EExtended strand (participates in β ladder)trans-130.5142.6-179.8-68.2-93.6000110L56 Q98 W101 Y106 F112 T124 V125 D127 L151L56-F110 HydrophobicContact CD1-CD1 4.13Å; L56-F110 HydrophobicContact CD1-CE1 4.02Å; Q98-F110 HydrophobicContact CB-CD1 4.45Å; Q98-F110 VanDerWaalsContact OE1-CA 3.29Å; W101-F110 HydrophobicContact CD2-CZ 4.45Å; W101-F110 AromaticContact CE2-CZ 3.83Å; W101-F110 AromaticContact CH2-CE1 4Å; W101-F110 HydrophobicContact CH2-CE1 4Å; W101-F110 HydrophobicContact CH2-CE2 4.21Å; W101-F110 AromaticContact CH2-CZ 3.53Å; W101-F110 HydrophobicContact CH2-CZ 3.53Å; W101-F110 HydrophobicContact CZ2-CE1 4.24Å; W101-F110 AromaticContact CZ2-CE2 3.66Å; W101-F110 HydrophobicContact CZ2-CE2 3.66Å; W101-F110 AromaticContact CZ2-CZ 3.34Å; W101-F110 HydrophobicContact CZ2-CZ 3.34Å; W101-F110 HydrophobicContact CZ3-CE1 4.44Å; W101-F110 HydrophobicContact CZ3-CZ 4.13Å; Y106-F110 HydrophobicContact CE2-CE2 4.31Å; Y106-F110 HydrophobicContact CE2-CZ 4.49Å; F110-F112 HydrophobicContact CB-CE2 3.72Å; F110-F112 HydrophobicContact CB-CZ 4.12Å; F110-T124 WeakPolarHBondContact O-CA 3.42Å; F110-V125 PolarHBondContact N-O 3.05Å; F110-V125 PolarHBondContact O-N 3.2Å; F110-D127 HydrophobicContact CD2-CB 3.84Å; F110-D127 HydrophobicContact CE2-CB 3.63Å; F110-L151 HydrophobicContact CD1-CD1 4.25Å; F110-L151 HydrophobicContact CD2-CD1 4.12Å; F110-L151 HydrophobicContact CE1-CD1 4.41Å; F110-L151 HydrophobicContact CE2-CD1 4.29Å; F110-L151 HydrophobicContact CG-CD1 4.1Å; F110-L151 HydrophobicContact CZ-CD1 4.43Å
111R97.6Very high93.2Very high105 Ų10552.2 Ų52.240%0.39627%0.271SS..EExtended strand (participates in β ladder)trans-115.7143.9-177.1-61-165.1-61-80.2-5.6110.9Q98 E122 V123 T124Q98-R111 PolarHBondContact NE2-O 2.95Å; Q98-R111 PolarHBondContact OE1-O 2.89Å; R111-E122 IonicContact NE-OE2 3.95Å; R111-V123 CarbonylContact C-O 3.52Å; R111-V123 WeakPolarHBondContact CA-O 3.29Å; R111-T124 HydrophobicContact CG-CG2 4.29Å
112F98.3Very high93.5Very high0 Ų056.6 Ų56.60%029%0.292CS..EExtended strand (participates in β ladder)trans-135.5144-178.9-59.6-93.4000109.3V93 F94 F110 E122 V123 V125 L151 L152 A155V93-F112 CarbonylContact O-C 3.57Å; V93-F112 VanDerWaalsContact O-CA 3.25Å; V93-F112 WeakPolarHBondContact O-CA 3.33Å; F94-F112 HydrophobicContact CD1-CD1 4.26Å; F94-F112 AromaticContact CD1-CE1 3.86Å; F94-F112 HydrophobicContact CD1-CE1 3.86Å; F94-F112 AromaticContact CE1-CD1 3.96Å; F94-F112 HydrophobicContact CE1-CD1 3.96Å; F94-F112 AromaticContact CE1-CE1 3.25Å; F94-F112 HydrophobicContact CE1-CE1 3.25Å; F94-F112 HydrophobicContact CE1-CZ 4.11Å; F94-F112 HydrophobicContact CE2-CE1 4.45Å; F94-F112 HydrophobicContact CZ-CD1 4.06Å; F94-F112 AromaticContact CZ-CE1 3.56Å; F94-F112 HydrophobicContact CZ-CE1 3.56Å; F110-F112 HydrophobicContact CB-CE2 3.72Å; F110-F112 HydrophobicContact CB-CZ 4.12Å; F112-E122 CarbonylContact O-C 3.5Å; F112-E122 WeakPolarHBondContact O-CA 3.46Å; F112-V123 PolarHBondContact N-O 3.47Å; F112-V123 PolarHBondContact O-N 2.72Å; F112-V125 HydrophobicContact CD2-CG2 4.15Å; F112-V125 HydrophobicContact CE2-CG2 3.61Å; F112-L151 HydrophobicContact CE1-CB 4.45Å; F112-L151 HydrophobicContact CE2-CB 4.38Å; F112-L151 HydrophobicContact CZ-CB 3.62Å; F112-L152 HydrophobicContact CD1-CB 4.33Å; F112-L152 HydrophobicContact CD1-CD1 3.45Å; F112-L152 VanDerWaalsContact CD1-CD1 3.45Å; F112-L152 HydrophobicContact CD1-CG 4.49Å; F112-L152 HydrophobicContact CE1-CB 3.96Å; F112-L152 HydrophobicContact CE1-CD1 3.97Å; F112-L152 HydrophobicContact CG-CD1 4.27Å; F112-A155 HydrophobicContact CB-CB 4.11Å; F112-A155 HydrophobicContact CD1-CB 4.44Å; F112-A155 HydrophobicContact CD2-CB 3.49Å; F112-A155 VanDerWaalsContact CD2-CB 3.49Å; F112-A155 HydrophobicContact CE2-CB 4.06Å; F112-A155 HydrophobicContact CG-CB 3.75Å
113L98.3Very high94Very high42 Ų4253.2 Ų53.222%0.2226%0.255CS..EExtended strand (participates in β ladder)trans-106.4117.4166.7-57.7-177.8000108.9K92 V93 P95 W120 T121 E122K92-L113 WeakPolarHBondContact O-CB 3.26Å; K92-L113 WeakPolarHBondContact O-CD1 3.4Å; V93-L113 WeakPolarHBondContact CA-O 3.29Å; V93-L113 PolarHBondContact O-N 2.76Å; P95-L113 HydrophobicContact CG-CD1 4.35Å; P95-L113 HydrophobicContact CG-CG 4.02Å; L113-W120 HydrophobicContact CB-CE3 3.87Å; L113-W120 WeakPolarHBondContact O-CZ3 3.28Å; L113-T121 WeakPolarHBondContact CA-O 3.3Å; L113-E122 HydrophobicContact CD2-CB 3.73Å; L113-E122 HydrophobicContact CD2-CG 4.06Å
114I98.3Very high94.3Very high0 Ų052.7 Ų52.70%025%0.251CS..EExtended strand (participates in β ladder)trans-118.1128.6177.1-61.3161.9000107.8Q116 T121 V123 A155 Y156 L159 D177I114-Q116 PolarHBondContact O-N 2.89Å; I114-T121 PolarHBondContact N-O 2.66Å; I114-T121 WeakPolarHBondContact O-CB 3.35Å; I114-T121 PolarHBondContact O-N 3.42Å; I114-V123 HydrophobicContact CD1-CG2 4.17Å; I114-A155 HydrophobicContact CD1-CB 4.29Å; I114-Y156 HydrophobicContact CD1-CD2 4.18Å; I114-Y156 HydrophobicContact CG2-CD2 4.21Å; I114-Y156 HydrophobicContact CG2-CE2 4.27Å; I114-L159 HydrophobicContact CB-CD2 3.97Å; I114-L159 HydrophobicContact CD1-CD2 4.15Å; I114-L159 HydrophobicContact CG2-CD2 3.56Å; I114-D177 HydrophobicContact CG2-CB 4.09Å
115W96.3Very high94.8Very high9 Ų947.6 Ų47.63%0.03422%0.215CC..EExtended strand (participates in β ladder)trans-71.5127.3179.4-171.893.4000110.1G118 H119 W120 V176 D177 G180 L388 L480 R482W115-G118 VanDerWaalsContact CH2-N 3.33Å; W115-H119 WeakPolarHBondContact CA-O 3.39Å; W115-W120 HydrophobicContact CB-CD2 4.18Å; W115-W120 HydrophobicContact CB-CE3 4.1Å; W115-W120 HydrophobicContact CB-CH2 4.2Å; W115-W120 HydrophobicContact CB-CZ2 4.23Å; W115-W120 HydrophobicContact CB-CZ3 4.12Å; W115-W120 AromaticContact CD1-CE2 3.85Å; W115-W120 AromaticContact CD1-NE1 3.72Å; W115-V176 HydrophobicContact CE3-CG1 3.71Å; W115-V176 HydrophobicContact CH2-CG1 4.19Å; W115-V176 HydrophobicContact CZ3-CG1 3.45Å; W115-V176 VanDerWaalsContact CZ3-CG1 3.45Å; W115-D177 WeakPolarHBondContact CA-O 3.47Å; W115-D177 VanDerWaalsContact CB-O 3.31Å; W115-D177 WeakPolarHBondContact CB-O 3.33Å; W115-D177 PolarHBondContact N-O 3Å; W115-D177 WeakPolarHBondContact O-CA 3.23Å; W115-G180 VanDerWaalsContact CG-CA 3.44Å; W115-L388 HydrophobicContact CH2-CD1 3.84Å; W115-L388 HydrophobicContact CZ3-CD1 3.84Å; W115-L480 HydrophobicContact CH2-CD2 4.21Å; W115-L480 HydrophobicContact CZ2-CD2 4.24Å; W115-R482 VanDerWaalsContact CZ2-NH1 3.33Å
116Q89.8Confident95.1Very high31 Ų3140 Ų4015%0.14519%0.186CC..EExtended strand (participates in β ladder)trans-136.4121.4176.3-69.6-63.3-55.400109.5I114 G118 H119 L159 D177I114-Q116 PolarHBondContact O-N 2.89Å; Q116-G118 PolarHBondContact O-N 2.97Å; Q116-H119 PolarHBondContact N-O 3.44Å; Q116-H119 PolarHBondContact O-N 2.83Å; Q116-H119 VanDerWaalsContact O-O 3.11Å; Q116-L159 HydrophobicContact CG-CD1 4.21Å; Q116-L159 HydrophobicContact CG-CD2 3.69Å; Q116-L159 HydrophobicContact CG-CG 4.33Å; Q116-D177 PolarHBondContact NE2-OD2 2.84Å
117Q83Confident95.2Very high76 Ų7639 Ų3936%0.35518%0.182SC..THydrogen-bonded Turntrans52.739.4164.4-54.7170.418.800113.9H119 H390Q117-H119 PolarHBondContact O-ND1 2.97Å; Q117-H390 PolarHBondContact OE1-CD2 2.87Å; Q117-H390 PolarHBondContact OE1-NE2 2.64Å
118G87.7Confident95.4Very high8 Ų834.9 Ų34.98%0.08217%0.167CC..THydrogen-bonded Turntrans102.4-7.7178.800000115.4W115 Q116 Q347W115-G118 VanDerWaalsContact CH2-N 3.33Å; Q116-G118 PolarHBondContact O-N 2.97Å; G118-Q347 PolarHBondContact O-NE2 2.84Å; G118-Q347 PolarHBondContact O-OE1 3.24Å
119H91.8Very high95.5Very high123 Ų12335 Ų3557%0.56917%0.167SC*.EExtended strand (participates in β ladder)trans-139.2146.7-171.9-49.588.5000111.8W115 Q116 Q117 T121W115-H119 WeakPolarHBondContact CA-O 3.39Å; Q116-H119 PolarHBondContact N-O 3.44Å; Q116-H119 PolarHBondContact O-N 2.83Å; Q116-H119 VanDerWaalsContact O-O 3.11Å; Q117-H119 PolarHBondContact O-ND1 2.97Å; H119-T121 PolarHBondContact O-N 3.3Å
120W95.1Very high95.6Very high72 Ų7233.8 Ų33.827%0.27316%0.159SC..EExtended strand (participates in β ladder)trans-76.9119.6171.1-69.690.3000109.1K92 V93 L113 W115 T179K92-W120 HydrophobicContact CD-CD2 4.33Å; K92-W120 HydrophobicContact CD-CH2 3.83Å; K92-W120 HydrophobicContact CD-CZ2 3.54Å; K92-W120 HydrophobicContact CD-CZ3 4.35Å; K92-W120 VanDerWaalsContact CE-CZ2 3.42Å; K92-W120 VanDerWaalsContact CE-NE1 3.28Å; K92-W120 HydrophobicContact CG-CD2 4.48Å; K92-W120 HydrophobicContact CG-CE3 4.44Å; K92-W120 HydrophobicContact CG-CH2 4.26Å; K92-W120 HydrophobicContact CG-CZ2 4.34Å; K92-W120 HydrophobicContact CG-CZ3 4.32Å; K92-W120 VanDerWaalsContact NZ-NE1 3.18Å; V93-W120 HydrophobicContact CG2-CZ3 4.17Å; L113-W120 HydrophobicContact CB-CE3 3.87Å; L113-W120 WeakPolarHBondContact O-CZ3 3.28Å; W115-W120 HydrophobicContact CB-CD2 4.18Å; W115-W120 HydrophobicContact CB-CE3 4.1Å; W115-W120 HydrophobicContact CB-CH2 4.2Å; W115-W120 HydrophobicContact CB-CZ2 4.23Å; W115-W120 HydrophobicContact CB-CZ3 4.12Å; W115-W120 AromaticContact CD1-CE2 3.85Å; W115-W120 AromaticContact CD1-NE1 3.72Å; W120-T179 WeakPolarHBondContact CZ2-O 3.25Å
121T95.9Very high95.5Very high54 Ų5433.8 Ų33.833%0.33116%0.159SC..EExtended strand (participates in β ladder)trans-103.1125.8-179-57.20000108.8L113 I114 H119L113-T121 WeakPolarHBondContact CA-O 3.3Å; I114-T121 PolarHBondContact N-O 2.66Å; I114-T121 WeakPolarHBondContact O-CB 3.35Å; I114-T121 PolarHBondContact O-N 3.42Å; H119-T121 PolarHBondContact O-N 3.3Å
122E97.4Very high95.2Very high115 Ų11530.7 Ų30.754%0.53715%0.149SC..EExtended strand (participates in β ladder)trans-76.7126.3173-171.4175.993.700110.3R111 F112 L113R111-E122 IonicContact NE-OE2 3.95Å; F112-E122 CarbonylContact O-C 3.5Å; F112-E122 WeakPolarHBondContact O-CA 3.46Å; L113-E122 HydrophobicContact CD2-CB 3.73Å; L113-E122 HydrophobicContact CD2-CG 4.06Å
123V97.8Very high94.7Very high10 Ų1038.2 Ų38.26%0.06119%0.19CC..EExtended strand (participates in β ladder)trans-118.7118.6174.1-174.40000107.8R111 F112 I114 V125 A155 K158 L159R111-V123 CarbonylContact C-O 3.52Å; R111-V123 WeakPolarHBondContact CA-O 3.29Å; F112-V123 PolarHBondContact N-O 3.47Å; F112-V123 PolarHBondContact O-N 2.72Å; I114-V123 HydrophobicContact CD1-CG2 4.17Å; V123-V125 HydrophobicContact CG1-CG1 4.3Å; V123-A155 HydrophobicContact CB-CB 4.38Å; V123-A155 HydrophobicContact CG1-CB 3.99Å; V123-K158 HydrophobicContact CG1-CB 4.47Å; V123-K158 HydrophobicContact CG1-CD 3.94Å; V123-K158 HydrophobicContact CG1-CG 4.31Å; V123-L159 HydrophobicContact CG2-CD1 4.16Å
124T97.5Very high94Very high34 Ų3438.3 Ų38.321%0.20919%0.194CC..EExtended strand (participates in β ladder)trans-102.4132173.4-600000108.9F15 S109 F110 R111 K158F15-T124 HydrophobicContact CE1-CG2 3.93Å; F15-T124 HydrophobicContact CZ-CG2 4.08Å; S109-T124 VanDerWaalsContact OG-CG2 3.3Å; S109-T124 WeakPolarHBondContact OG-CG2 3.39Å; F110-T124 WeakPolarHBondContact O-CA 3.42Å; R111-T124 HydrophobicContact CG-CG2 4.29Å; T124-K158 PolarHBondContact O-NZ 2.85Å
125V98.1Very high93.7Very high0 Ų042 Ų420%022%0.219CC..EExtended strand (participates in β ladder)trans-129.8151.8174.4-65.40000110.6D17 F110 F112 V123 K154 A155 K158D17-V125 WeakPolarHBondContact OD2-CA 3.3Å; F110-V125 PolarHBondContact N-O 3.05Å; F110-V125 PolarHBondContact O-N 3.2Å; F112-V125 HydrophobicContact CD2-CG2 4.15Å; F112-V125 HydrophobicContact CE2-CG2 3.61Å; V123-V125 HydrophobicContact CG1-CG1 4.3Å; V125-K154 HydrophobicContact CB-CD 4.26Å; V125-K154 HydrophobicContact CG1-CG 4.34Å; V125-A155 HydrophobicContact CG1-CB 4.08Å; V125-A155 HydrophobicContact CG2-CB 4.38Å; V125-K158 HydrophobicContact CG1-CB 4.36Å; V125-K158 HydrophobicContact CG1-CD 3.79Å
126D97.4Very high93.6Very high0 Ų043 Ų430%023%0.225CC..EExtended strand (participates in β ladder)trans-75.5163.6161.473.358000111.4F15 D17 G108 R128 K154F15-D126 HydrophobicContact CD1-CB 3.64Å; F15-D126 HydrophobicContact CE1-CB 4.14Å; F15-D126 WeakPolarHBondContact O-CB 3.33Å; D17-D126 HydrophobicContact CB-CB 4.29Å; D17-D126 VanDerWaalsContact CB-OD2 3.26Å; D17-D126 WeakPolarHBondContact CB-OD2 3.3Å; D17-D126 PolarHBondContact N-OD2 3.49Å; G108-D126 WeakPolarHBondContact O-CA 3.25Å; G108-D126 WeakPolarHBondContact O-CB 3.27Å; D126-R128 WeakPolarHBondContact OD1-CB 3.44Å; D126-R128 WeakPolarHBondContact OD1-CG 3.22Å; D126-R128 PolarHBondContact OD1-N 2.77Å; D126-R128 IonicContact OD1-NE 2.65Å; D126-R128 PolarHBondContact OD1-NE 2.67Å; D126-R128 IonicContact OD2-CZ 2.8Å; D126-R128 VanDerWaalsContact OD2-CZ 3.32Å; D126-R128 IonicContact OD2-NE 2.88Å; D126-R128 PolarHBondContact OD2-NE 3.17Å; D126-R128 VanDerWaalsContact OD2-NE 3.15Å; D126-R128 IonicContact OD2-NH2 3.32Å; D126-R128 PolarHBondContact OD2-NH2 3.41Å; D126-K154 PolarHBondContact O-NZ 3.46Å; D126-K154 IonicContact OD1-NZ 2.72Å; D126-K154 PolarHBondContact OD1-NZ 2.99Å; D126-K154 IonicContact OD2-NZ 3.66Å
127D97.1Very high93.8Very high0 Ų041.8 Ų41.80%022%0.22CC..SBendtrans-90.515.2-178.468.8-7.3000115.4R46 P47 W101 Y106 G108 F110 L129 L151R46-D127 VanDerWaalsContact CD-OD1 3.31Å; R46-D127 WeakPolarHBondContact CD-OD1 3.49Å; R46-D127 WeakPolarHBondContact CG-OD1 3.29Å; R46-D127 IonicContact CZ-OD1 3.61Å; R46-D127 IonicContact NE-OD1 3Å; R46-D127 IonicContact NH1-OD1 3.22Å; R46-D127 PolarHBondContact NH1-OD1 3.03Å; P47-D127 WeakPolarHBondContact CD-O 3.19Å; P47-D127 HydrophobicContact CG-CB 4.48Å; W101-D127 HydrophobicContact CZ2-CB 4.37Å; W101-D127 PolarHBondContact NE1-OD2 3.13Å; Y106-D127 VanDerWaalsContact CE2-OD2 3.25Å; Y106-D127 WeakPolarHBondContact CE2-OD2 3.07Å; Y106-D127 VanDerWaalsContact CZ-OD2 3.3Å; Y106-D127 VanDerWaalsContact OH-CG 3.31Å; Y106-D127 PolarHBondContact OH-OD1 3.25Å; Y106-D127 PolarHBondContact OH-OD2 3.07Å; G108-D127 PolarHBondContact O-N 3.39Å; F110-D127 HydrophobicContact CD2-CB 3.84Å; F110-D127 HydrophobicContact CE2-CB 3.63Å; D127-L129 PolarHBondContact O-N 3.03Å; D127-L151 HydrophobicContact CB-CD2 3.81Å
128R97.5Very high94.4Very high25 Ų2538.3 Ų38.39%0.09420%0.203CC..  trans-72124.9170.3-61.1173.4-71.1-168.62.5109.1E16 I22 W44 R45 R46 D126 K154E16-R128 IonicContact OE1-NH1 2.74Å; E16-R128 IonicContact OE2-NH1 3.78Å; I22-R128 HydrophobicContact CG2-CB 4.08Å; W44-R128 HydrophobicContact CB-CB 4.3Å; W44-R128 HydrophobicContact CE3-CB 4.19Å; W44-R128 WeakPolarHBondContact CZ3-O 3.19Å; R45-R128 CarbonylContact O-C 3.56Å; R45-R128 WeakPolarHBondContact O-CA 3.39Å; R46-R128 HydrophobicContact CG-CG 3.73Å; D126-R128 WeakPolarHBondContact OD1-CB 3.44Å; D126-R128 WeakPolarHBondContact OD1-CG 3.22Å; D126-R128 PolarHBondContact OD1-N 2.77Å; D126-R128 IonicContact OD1-NE 2.65Å; D126-R128 PolarHBondContact OD1-NE 2.67Å; D126-R128 IonicContact OD2-CZ 2.8Å; D126-R128 VanDerWaalsContact OD2-CZ 3.32Å; D126-R128 IonicContact OD2-NE 2.88Å; D126-R128 PolarHBondContact OD2-NE 3.17Å; D126-R128 VanDerWaalsContact OD2-NE 3.15Å; D126-R128 IonicContact OD2-NH2 3.32Å; D126-R128 PolarHBondContact OD2-NH2 3.41Å; R128-K154 WeakPolarHBondContact O-CE 3.18Å; R128-K154 PolarHBondContact O-NZ 3.33Å
129L98.1Very high94.8Very high2 Ų238 Ų381%0.0120%0.2CC..EExtended strand (participates in β ladder)trans-118.3145.4-176-67.7168.6000111.1W44 R45 P47 D127 C131 L136 F147 A150 L151 K154W44-L129 WeakPolarHBondContact CA-O 3.28Å; R45-L129 PolarHBondContact N-O 2.82Å; R45-L129 PolarHBondContact O-N 2.97Å; P47-L129 HydrophobicContact CG-CD1 4.36Å; D127-L129 PolarHBondContact O-N 3.03Å; L129-C131 PolarHBondContact O-N 3.42Å; L129-L136 HydrophobicContact CB-CD2 3.61Å; L129-L136 HydrophobicContact CD1-CD2 3.76Å; L129-L136 HydrophobicContact CG-CD2 4.29Å; L129-F147 HydrophobicContact CD1-CD1 3.72Å; L129-F147 HydrophobicContact CD1-CE1 4.37Å; L129-A150 HydrophobicContact CD1-CB 3.79Å; L129-A150 HydrophobicContact CD2-CB 3.99Å; L129-L151 HydrophobicContact CD1-CD2 4.41Å; L129-L151 HydrophobicContact CD2-CD2 4.1Å; L129-L151 HydrophobicContact CG-CD2 4.37Å; L129-K154 HydrophobicContact CD2-CB 4.41Å; L129-K154 HydrophobicContact CD2-CD 4.31Å
130P96.9Very high94.9Very high4 Ų438.1 Ų38.13%0.02620%0.195CC..EExtended strand (participates in β ladder)trans-63.1125.2175.1-26.238.1000112.9L27 I42 T43 W44 C137 F138 Y163L27-P130 HydrophobicContact CD2-CB 4Å; L27-P130 HydrophobicContact CD2-CG 3.69Å; I42-P130 HydrophobicContact CG2-CB 3.73Å; T43-P130 CarbonylContact O-C 3.41Å; W44-P130 HydrophobicContact CD2-CG 4.47Å; W44-P130 HydrophobicContact CE3-CG 4.14Å; W44-P130 HydrophobicContact CH2-CG 3.93Å; W44-P130 HydrophobicContact CZ2-CG 4.24Å; W44-P130 HydrophobicContact CZ3-CG 3.86Å; P130-C137 HydrophobicContact CB-CB 4.3Å; P130-C137 PolarHBondContact O-N 2.92Å; P130-F138 HydrophobicContact CB-CD2 3.92Å; P130-F138 HydrophobicContact CB-CE2 3.73Å; P130-F138 HydrophobicContact CG-CD2 3.85Å; P130-F138 HydrophobicContact CG-CE2 3.67Å; P130-Y163 HydrophobicContact CG-CD2 4.36Å; P130-Y163 HydrophobicContact CG-CE2 3.71Å
131C95.6Very high94.8Very high0 Ų035 Ų350%018%0.184CC..EExtended strand (participates in β ladder)trans-136.4140.7-176-67.80000113.2T43 R45 L129 C135 C137T43-C131 PolarHBondContact N-O 2.89Å; T43-C131 PolarHBondContact O-N 2.79Å; T43-C131 PolarHBondContact OG1-O 3.2Å; R45-C131 HydrophobicContact CG-CB 4.34Å; L129-C131 PolarHBondContact O-N 3.42Å; C131-C135 CarbonylContact C-O 3.45Å; C131-C135 WeakPolarHBondContact CA-O 3.41Å; C131-C135 WeakPolarHBondContact CB-O 3.06Å; C131-C137 VanDerWaalsContact CA-SG 3.52Å
132M92.5Very high94.5Very high39 Ų3934 Ų3419%0.19218%0.176CC..EExtended strand (participates in β ladder)trans-118.2130.3165.5-76.1-175.3-52.900108L38 E41 I42 L70 S134 C135 C137L38-M132 HydrophobicContact CD1-CE 4.43Å; L38-M132 HydrophobicContact CD2-CE 4.21Å; L38-M132 HydrophobicContact CD2-SD 4.01Å; E41-M132 HydrophobicContact CB-CG 4.49Å; E41-M132 HydrophobicContact CB-SD 4.06Å; I42-M132 HydrophobicContact CG1-CG 4.23Å; I42-M132 HydrophobicContact CG1-SD 4.47Å; L70-M132 HydrophobicContact CD1-CE 3.16Å; M132-S134 PolarHBondContact O-N 3Å; M132-S134 VanDerWaalsContact O-N 3.12Å; M132-C135 PolarHBondContact N-O 2.83Å; M132-C135 WeakPolarHBondContact O-CB 3.36Å; M132-C135 PolarHBondContact O-N 2.88Å; M132-C137 PolarHBondContact N-SG 3.47Å
133D86.9Confident94.3Very high158 Ų15829.2 Ų29.285%0.84516%0.155SC*.THydrogen-bonded Turntrans4940-175.8-60.7-37.6000113.7C135D133-C135 PolarHBondContact O-N 2.93Å
134S84.1Confident94Very high45 Ų4534.1 Ų34.132%0.31519%0.187SC..THydrogen-bonded Turntrans64.410.8-176.4-37.80000115.5R45 M132R45-S134 PolarHBondContact NH1-OG 2.91Å; R45-S134 PolarHBondContact NH2-OG 2.97Å; M132-S134 PolarHBondContact O-N 3Å; M132-S134 VanDerWaalsContact O-N 3.12Å
135C90.7Very high93.9Very high77 Ų7734.3 Ų34.352%0.5219%0.19SC..EExtended strand (participates in β ladder)trans-102.7142.3171.8-64.90000110.5C131 M132 D133 C137C131-C135 CarbonylContact C-O 3.45Å; C131-C135 WeakPolarHBondContact CA-O 3.41Å; C131-C135 WeakPolarHBondContact CB-O 3.06Å; M132-C135 PolarHBondContact N-O 2.83Å; M132-C135 WeakPolarHBondContact O-CB 3.36Å; M132-C135 PolarHBondContact O-N 2.88Å; D133-C135 PolarHBondContact O-N 2.93Å; C135-C137 PolarHBondContact O-N 3.4Å
136L95.3Very high93.8Very high31 Ų3134.5 Ų34.516%0.16219%0.191CC..EExtended strand (participates in β ladder)trans-58.1131.1174.5-67.7173.3000111I50 L129 R140 F147 A150I50-L136 HydrophobicContact CD1-CD2 3.89Å; L129-L136 HydrophobicContact CB-CD2 3.61Å; L129-L136 HydrophobicContact CD1-CD2 3.76Å; L129-L136 HydrophobicContact CG-CD2 4.29Å; L136-R140 HydrophobicContact CD1-CB 3.95Å; L136-F147 HydrophobicContact CD1-CD1 4.26Å; L136-F147 HydrophobicContact CD1-CE1 4.14Å; L136-A150 HydrophobicContact CD1-CB 4.15Å
137C93.8Very high93.8Very high4 Ų434.6 Ų34.63%0.02719%0.191CC..SBendtrans-74.8-39.8177.8-62.30000112G69 L70 P130 C131 M132 C135G69-C137 WeakPolarHBondContact CA-O 3.34Å; L70-C137 WeakPolarHBondContact CG-O 3.2Å; L70-C137 PolarHBondContact N-O 3.05Å; P130-C137 HydrophobicContact CB-CB 4.3Å; P130-C137 PolarHBondContact O-N 2.92Å; C131-C137 VanDerWaalsContact CA-SG 3.52Å; M132-C137 PolarHBondContact N-SG 3.47Å; C135-C137 PolarHBondContact O-N 3.4Å
138F95.3Very high93.8Very high4 Ų434.6 Ų34.62%0.01819%0.191CC..SBendtrans-105.2-147.8-172.7-53.2-45.1000110.3L27 I35 G69 L71 P130 E153 Y163L27-F138 HydrophobicContact CD2-CE2 3.79Å; L27-F138 HydrophobicContact CD2-CZ 4.1Å; I35-F138 HydrophobicContact CG2-CE1 4.5Å; G69-F138 WeakPolarHBondContact CA-O 3.37Å; L71-F138 HydrophobicContact CB-CD1 3.69Å; L71-F138 HydrophobicContact CB-CE1 4.19Å; L71-F138 HydrophobicContact CB-CG 4.36Å; P130-F138 HydrophobicContact CB-CD2 3.92Å; P130-F138 HydrophobicContact CB-CE2 3.73Å; P130-F138 HydrophobicContact CG-CD2 3.85Å; P130-F138 HydrophobicContact CG-CE2 3.67Å; F138-E153 WeakPolarHBondContact CB-OE2 3.39Å; F138-Y163 HydrophobicContact CB-CE1 4.45Å; F138-Y163 AromaticContact CD2-CD1 3.33Å; F138-Y163 HydrophobicContact CD2-CD1 3.33Å; F138-Y163 HydrophobicContact CD2-CD2 4.26Å; F138-Y163 AromaticContact CD2-CE1 3.33Å; F138-Y163 HydrophobicContact CD2-CE1 3.33Å; F138-Y163 HydrophobicContact CD2-CE2 4.27Å; F138-Y163 AromaticContact CD2-CG 3.8Å; F138-Y163 HydrophobicContact CD2-CG 3.8Å; F138-Y163 AromaticContact CD2-CZ 3.81Å; F138-Y163 AromaticContact CE2-CD1 3.46Å; F138-Y163 HydrophobicContact CE2-CD1 3.46Å; F138-Y163 VanDerWaalsContact CE2-CD1 3.46Å; F138-Y163 AromaticContact CE2-CD2 3.75Å; F138-Y163 HydrophobicContact CE2-CD2 3.75Å; F138-Y163 AromaticContact CE2-CE1 3.84Å; F138-Y163 HydrophobicContact CE2-CE1 3.84Å; F138-Y163 HydrophobicContact CE2-CE2 4.1Å; F138-Y163 AromaticContact CE2-CG 3.39Å; F138-Y163 HydrophobicContact CE2-CG 3.39Å; F138-Y163 HydrophobicContact CG-CD1 4.11Å; F138-Y163 HydrophobicContact CG-CE1 4.19Å; F138-Y163 HydrophobicContact CZ-CD1 4.34Å; F138-Y163 HydrophobicContact CZ-CG 4.14Å
139S95.2Very high93.7Very high0 Ų033.4 Ų33.40%019%0.187CC..  trans-63.6143.7-169.8-66.10000113.3K67 L77 A150 E153K67-S139 WeakPolarHBondContact O-CA 3.34Å; L77-S139 WeakPolarHBondContact CD1-OG 3.3Å; L77-S139 VanDerWaalsContact CD2-OG 3.23Å; L77-S139 WeakPolarHBondContact CD2-OG 3.42Å; S139-A150 WeakPolarHBondContact O-CB 3.45Å; S139-E153 VanDerWaalsContact CB-CD 3.5Å; S139-E153 WeakPolarHBondContact CB-OE1 3.31Å; S139-E153 PolarHBondContact N-OE1 3.02Å; S139-E153 VanDerWaalsContact N-OE1 3.11Å; S139-E153 PolarHBondContact N-OE2 3.38Å; S139-E153 VanDerWaalsContact N-OE2 3.08Å; S139-E153 PolarHBondContact OG-OE1 3.38Å
140R94.4Very high93.7Very high126 Ų12633.4 Ų33.448%0.47519%0.187SC..EExtended strand (participates in β ladder)trans-138.8162.6179.263.9-172.2178.3-173.6-0111.1A66 K67 L136A66-R140 CarbonylContact C-O 3.58Å; K67-R140 HydrophobicContact CB-CG 3.99Å; K67-R140 PolarHBondContact N-O 2.84Å; K67-R140 PolarHBondContact O-N 3.24Å; L136-R140 HydrophobicContact CD1-CB 3.95Å
141C93.5Very high93.8Very high6 Ų633.2 Ų33.24%0.04119%0.186CC..EExtended strand (participates in β ladder)trans-84167.2172-57.60000111H65 S143 A146 W148H65-C141 WeakPolarHBondContact O-CA 3.43Å; C141-S143 VanDerWaalsContact C-N 3.25Å; C141-S143 WeakPolarHBondContact CB-O 3.25Å; C141-A146 HydrophobicContact CB-CB 3.88Å; C141-A146 PolarHBondContact SG-O 3.05Å; C141-W148 PolarHBondContact SG-NE1 3.42Å
142H90.1Very high93.9Very high35 Ų3533.2 Ų33.216%0.16219%0.186CC..SBendtrans-62.9-37.5167.2-73.754.2000111L63 H65 K67 R268 E304L63-H142 HydrophobicContact CD2-CB 4.33Å; L63-H142 PolarHBondContact O-N 2.61Å; H65-H142 PolarHBondContact O-N 3.18Å; H65-H142 VanDerWaalsContact O-N 3.07Å; H65-H142 PolarHBondContact O-ND1 3.33Å; K67-H142 WeakPolarHBondContact CE-CD2 3.21Å; K67-H142 WeakPolarHBondContact CE-CE1 3.36Å; K67-H142 VanDerWaalsContact CE-CG 3.49Å; K67-H142 WeakPolarHBondContact CE-NE2 3.49Å; K67-H142 WeakPolarHBondContact CG-CE1 3.49Å; H142-R268 PolarHBondContact CE1-NH2 3.14Å; H142-R268 PolarHBondContact NE2-NH2 3.15Å; H142-E304 IonicContact CD2-OE2 3.53Å
143S92.9Very high94.2Very high13 Ų1331.4 Ų31.49%0.09118%0.177CC..SBendtrans-72.5123.7166.5175.20000110.3L63 C141 S145 A146L63-S143 PolarHBondContact O-N 2.87Å; C141-S143 VanDerWaalsContact C-N 3.25Å; C141-S143 WeakPolarHBondContact CB-O 3.25Å; S143-S145 PolarHBondContact O-N 3.07Å; S143-S145 PolarHBondContact OG-N 2.93Å; S143-S145 PolarHBondContact OG-OG 3.47Å; S143-S145 VanDerWaalsContact OG-OG 3.11Å; S143-A146 PolarHBondContact O-N 2.87Å
144P92.1Very high94.8Very high114 Ų11423.9 Ų23.974%0.7414%0.137SC*.THydrogen-bonded Turntrans-71.3-7177.530.6-36.1000113.4
145S94.8Very high95.5Very high38 Ų3821.8 Ų21.827%0.26612%0.122SC..THydrogen-bonded Turntrans-106.10.8178.363.50000113.7S53 P54 S55 S143 F147S53-S145 WeakPolarHBondContact O-CB 3.39Å; P54-S145 WeakPolarHBondContact CA-O 3.4Å; S55-S145 PolarHBondContact N-O 2.99Å; S143-S145 PolarHBondContact O-N 3.07Å; S143-S145 PolarHBondContact OG-N 2.93Å; S143-S145 PolarHBondContact OG-OG 3.47Å; S143-S145 VanDerWaalsContact OG-OG 3.11Å; S145-F147 VanDerWaalsContact O-CD2 3.3Å; S145-F147 WeakPolarHBondContact O-CD2 3.33Å; S145-F147 VanDerWaalsContact O-CE2 3.31Å; S145-F147 WeakPolarHBondContact O-CE2 3.48Å
146A95.9Very high95.8Very high3 Ų318.1 Ų18.13%0.02510%0.097CC..BIsolated β-bridgetrans-104131.4179.400000111.9S55 P58 C141 S143S55-A146 WeakPolarHBondContact O-CA 3.33Å; P58-A146 HydrophobicContact CB-CB 4.06Å; P58-A146 HydrophobicContact CG-CB 4.03Å; C141-A146 HydrophobicContact CB-CB 3.88Å; C141-A146 PolarHBondContact SG-O 3.05Å; S143-A146 PolarHBondContact O-N 2.87Å
147F97.1Very high95.9Very high2 Ų216.6 Ų16.61%0.0099%0.089CC..  trans-120.53.4-168.2-66.7-90.1000115.3P47 I50 P54 S55 L56 W101 L129 L136 S145 V149 A150 L151P47-F147 HydrophobicContact CB-CD1 4.11Å; P47-F147 HydrophobicContact CB-CD2 3.87Å; P47-F147 HydrophobicContact CB-CE1 3.99Å; P47-F147 HydrophobicContact CB-CE2 3.77Å; P47-F147 HydrophobicContact CB-CG 4.05Å; P47-F147 HydrophobicContact CB-CZ 3.82Å; P47-F147 HydrophobicContact CG-CB 4.46Å; P47-F147 HydrophobicContact CG-CD1 3.84Å; P47-F147 HydrophobicContact CG-CD2 4.25Å; P47-F147 HydrophobicContact CG-CE1 4.09Å; P47-F147 HydrophobicContact CG-CG 3.92Å; P47-F147 HydrophobicContact CG-CZ 4.42Å; I50-F147 HydrophobicContact CB-CE1 4.44Å; I50-F147 HydrophobicContact CB-CZ 4.3Å; I50-F147 HydrophobicContact CD1-CE1 4.03Å; I50-F147 HydrophobicContact CG2-CE1 4.29Å; I50-F147 HydrophobicContact CG2-CZ 4.2Å; P54-F147 HydrophobicContact CB-CD2 3.9Å; P54-F147 HydrophobicContact CB-CE2 3.57Å; S55-F147 PolarHBondContact O-N 2.93Å; L56-F147 PolarHBondContact O-N 3.06Å; W101-F147 HydrophobicContact CH2-CB 4.02Å; L129-F147 HydrophobicContact CD1-CD1 3.72Å; L129-F147 HydrophobicContact CD1-CE1 4.37Å; L136-F147 HydrophobicContact CD1-CD1 4.26Å; L136-F147 HydrophobicContact CD1-CE1 4.14Å; S145-F147 VanDerWaalsContact O-CD2 3.3Å; S145-F147 WeakPolarHBondContact O-CD2 3.33Å; S145-F147 VanDerWaalsContact O-CE2 3.31Å; S145-F147 WeakPolarHBondContact O-CE2 3.48Å; F147-V149 VanDerWaalsContact C-N 3.34Å; F147-V149 PolarHBondContact O-N 3.02Å; F147-A150 PolarHBondContact O-N 3.31Å; F147-L151 HydrophobicContact CB-CD1 4.25Å; F147-L151 HydrophobicContact CB-CG 4.5Å; F147-L151 WeakPolarHBondContact O-CG 3.32Å; F147-L151 PolarHBondContact O-N 3.34Å
148W96.6Very high96.1Very high0 Ų018.4 Ų18.40%010%0.097CC..Hα-helixtrans-56.9-42.6-17777.1-81.4000113.6L56 F57 A64 C80 L83 L84 F94 C141 L152L56-W148 HydrophobicContact CD1-CB 4.25Å; L56-W148 HydrophobicContact CG-CB 4.29Å; L56-W148 VanDerWaalsContact O-CB 3.25Å; L56-W148 WeakPolarHBondContact O-CB 3.35Å; L56-W148 PolarHBondContact O-N 2.77Å; F57-W148 HydrophobicContact CD1-CB 3.88Å; F57-W148 AromaticContact CD1-CD1 3.65Å; F57-W148 HydrophobicContact CD1-CD2 4.1Å; F57-W148 AromaticContact CD1-CG 3.57Å; F57-W148 HydrophobicContact CD1-CG 3.57Å; F57-W148 HydrophobicContact CE1-CB 3.51Å; F57-W148 AromaticContact CE1-CD1 3.83Å; F57-W148 AromaticContact CE1-CD2 3.48Å; F57-W148 HydrophobicContact CE1-CD2 3.48Å; F57-W148 VanDerWaalsContact CE1-CD2 3.48Å; F57-W148 AromaticContact CE1-CE3 3.9Å; F57-W148 HydrophobicContact CE1-CE3 3.9Å; F57-W148 AromaticContact CE1-CG 3.29Å; F57-W148 HydrophobicContact CE1-CG 3.29Å; F57-W148 HydrophobicContact CE2-CB 4.19Å; F57-W148 HydrophobicContact CG-CB 4.37Å; F57-W148 HydrophobicContact CG-CG 4.45Å; F57-W148 HydrophobicContact CZ-CB 3.68Å; F57-W148 HydrophobicContact CZ-CD2 4.24Å; F57-W148 HydrophobicContact CZ-CE3 4.37Å; F57-W148 AromaticContact CZ-CG 3.97Å; F57-W148 HydrophobicContact CZ-CG 3.97Å; A64-W148 WeakPolarHBondContact O-CZ2 3.35Å; A64-W148 PolarHBondContact O-NE1 3.33Å; C80-W148 HydrophobicContact CB-CH2 3.86Å; C80-W148 HydrophobicContact CB-CZ3 4.36Å; L83-W148 HydrophobicContact CD2-CZ3 4.3Å; L84-W148 HydrophobicContact CD1-CH2 4.2Å; L84-W148 HydrophobicContact CD1-CZ2 3.6Å; L84-W148 HydrophobicContact CD2-CH2 3.89Å; L84-W148 HydrophobicContact CD2-CZ2 3.45Å; L84-W148 VanDerWaalsContact CD2-CZ2 3.45Å; L84-W148 HydrophobicContact CG-CH2 3.68Å; L84-W148 HydrophobicContact CG-CZ2 3.46Å; L84-W148 VanDerWaalsContact CG-CZ2 3.46Å; F94-W148 HydrophobicContact CE1-CB 3.93Å; F94-W148 AromaticContact CE2-CE3 3.68Å; F94-W148 HydrophobicContact CE2-CE3 3.68Å; F94-W148 HydrophobicContact CE2-CZ3 4.17Å; F94-W148 HydrophobicContact CZ-CB 3.98Å; F94-W148 HydrophobicContact CZ-CD2 4.38Å; F94-W148 AromaticContact CZ-CE3 3.53Å; F94-W148 HydrophobicContact CZ-CE3 3.53Å; F94-W148 HydrophobicContact CZ-CZ3 4.37Å; C141-W148 PolarHBondContact SG-NE1 3.42Å; W148-L152 HydrophobicContact CE3-CD2 4.42Å; W148-L152 HydrophobicContact CZ3-CD2 4.01Å; W148-L152 VanDerWaalsContact O-CB 3.3Å; W148-L152 WeakPolarHBondContact O-CB 3.26Å; W148-L152 PolarHBondContact O-N 3.32Å
149V96.9Very high96Very high0 Ų020.6 Ų20.60%011%0.108CC..Hα-helixtrans-64.9-48.6179.7-176.70000110.6A66 L77 F147 L151 L152 E153A66-V149 HydrophobicContact CB-CG1 3.88Å; A66-V149 HydrophobicContact CB-CG2 3.96Å; L77-V149 HydrophobicContact CD2-CG1 3.92Å; F147-V149 VanDerWaalsContact C-N 3.34Å; F147-V149 PolarHBondContact O-N 3.02Å; V149-L151 VanDerWaalsContact C-N 3.3Å; V149-L151 PolarHBondContact O-N 3.23Å; V149-L152 PolarHBondContact O-N 2.99Å; V149-E153 VanDerWaalsContact O-CB 3.29Å; V149-E153 WeakPolarHBondContact O-CB 3.37Å; V149-E153 PolarHBondContact O-N 3.34Å
150A97.9Very high95.8Very high2 Ų222.9 Ų22.92%0.01712%0.119CC..Hα-helixtrans-61.9-40-177.400000111.7L129 L136 S139 F147 K154L129-A150 HydrophobicContact CD1-CB 3.79Å; L129-A150 HydrophobicContact CD2-CB 3.99Å; L136-A150 HydrophobicContact CD1-CB 4.15Å; S139-A150 WeakPolarHBondContact O-CB 3.45Å; F147-A150 PolarHBondContact O-N 3.31Å; A150-K154 WeakPolarHBondContact O-CB 3.34Å; A150-K154 PolarHBondContact O-N 3.37Å
151L98.3Very high95.7Very high0 Ų019 Ų190%012%0.118CC..Hα-helixtrans-72.7-36.9177.3-65.4168.5000112.4L56 W101 F110 F112 D127 L129 F147 V149 K154 A155L56-L151 HydrophobicContact CD1-CD1 3.78Å; W101-L151 HydrophobicContact CH2-CD1 3.76Å; W101-L151 HydrophobicContact CZ2-CD1 4.04Å; F110-L151 HydrophobicContact CD1-CD1 4.25Å; F110-L151 HydrophobicContact CD2-CD1 4.12Å; F110-L151 HydrophobicContact CE1-CD1 4.41Å; F110-L151 HydrophobicContact CE2-CD1 4.29Å; F110-L151 HydrophobicContact CG-CD1 4.1Å; F110-L151 HydrophobicContact CZ-CD1 4.43Å; F112-L151 HydrophobicContact CE1-CB 4.45Å; F112-L151 HydrophobicContact CE2-CB 4.38Å; F112-L151 HydrophobicContact CZ-CB 3.62Å; D127-L151 HydrophobicContact CB-CD2 3.81Å; L129-L151 HydrophobicContact CD1-CD2 4.41Å; L129-L151 HydrophobicContact CD2-CD2 4.1Å; L129-L151 HydrophobicContact CG-CD2 4.37Å; F147-L151 HydrophobicContact CB-CD1 4.25Å; F147-L151 HydrophobicContact CB-CG 4.5Å; F147-L151 WeakPolarHBondContact O-CG 3.32Å; F147-L151 PolarHBondContact O-N 3.34Å; V149-L151 VanDerWaalsContact C-N 3.3Å; V149-L151 PolarHBondContact O-N 3.23Å; L151-K154 WeakPolarHBondContact O-CB 3.44Å; L151-K154 PolarHBondContact O-N 2.93Å; L151-A155 PolarHBondContact O-N 3.08Å
152L98.5Very high95.8Very high0 Ų018.8 Ų18.80%012%0.117CC..Hα-helixtrans-67.4-42.4174.8-175.667.4000111.5F76 L83 V93 F94 F112 W148 V149 K154 A155 Y156 L178F76-L152 HydrophobicContact CZ-CD2 4.09Å; F76-L152 HydrophobicContact CZ-CG 3.95Å; L83-L152 HydrophobicContact CD2-CD2 4.07Å; V93-L152 HydrophobicContact CG1-CD1 3.53Å; V93-L152 HydrophobicContact CG1-CD2 4.45Å; F94-L152 HydrophobicContact CE2-CD1 4.23Å; F94-L152 HydrophobicContact CE2-CD2 4.07Å; F94-L152 HydrophobicContact CE2-CG 4.49Å; F94-L152 HydrophobicContact CZ-CB 3.91Å; F94-L152 HydrophobicContact CZ-CD1 4.26Å; F94-L152 HydrophobicContact CZ-CD2 4.26Å; F94-L152 HydrophobicContact CZ-CG 4.36Å; F112-L152 HydrophobicContact CD1-CB 4.33Å; F112-L152 HydrophobicContact CD1-CD1 3.45Å; F112-L152 VanDerWaalsContact CD1-CD1 3.45Å; F112-L152 HydrophobicContact CD1-CG 4.49Å; F112-L152 HydrophobicContact CE1-CB 3.96Å; F112-L152 HydrophobicContact CE1-CD1 3.97Å; F112-L152 HydrophobicContact CG-CD1 4.27Å; W148-L152 HydrophobicContact CE3-CD2 4.42Å; W148-L152 HydrophobicContact CZ3-CD2 4.01Å; W148-L152 VanDerWaalsContact O-CB 3.3Å; W148-L152 WeakPolarHBondContact O-CB 3.26Å; W148-L152 PolarHBondContact O-N 3.32Å; V149-L152 PolarHBondContact O-N 2.99Å; L152-K154 VanDerWaalsContact C-N 3.3Å; L152-K154 PolarHBondContact O-N 3.28Å; L152-A155 PolarHBondContact O-N 2.83Å; L152-Y156 WeakPolarHBondContact O-CB 3.33Å; L152-Y156 PolarHBondContact O-N 3.45Å; L152-L178 HydrophobicContact CD1-CD2 4.44Å; L152-L178 HydrophobicContact CD2-CD2 4.26Å
153E98.6Very high96Very high2 Ų217.1 Ų17.11%0.00911%0.109CC..Hα-helixtrans-58.4-43.2173-174.1-167.8-126.100110.4F76 F138 S139 V149 Y156 A157 Y163 L166F76-E153 HydrophobicContact CE1-CB 3.95Å; F76-E153 HydrophobicContact CE1-CG 4.31Å; F138-E153 WeakPolarHBondContact CB-OE2 3.39Å; S139-E153 VanDerWaalsContact CB-CD 3.5Å; S139-E153 WeakPolarHBondContact CB-OE1 3.31Å; S139-E153 PolarHBondContact N-OE1 3.02Å; S139-E153 VanDerWaalsContact N-OE1 3.11Å; S139-E153 PolarHBondContact N-OE2 3.38Å; S139-E153 VanDerWaalsContact N-OE2 3.08Å; S139-E153 PolarHBondContact OG-OE1 3.38Å; V149-E153 VanDerWaalsContact O-CB 3.29Å; V149-E153 WeakPolarHBondContact O-CB 3.37Å; V149-E153 PolarHBondContact O-N 3.34Å; E153-Y156 PolarHBondContact O-N 3.12Å; E153-A157 WeakPolarHBondContact O-CB 3.32Å; E153-A157 PolarHBondContact O-N 3.43Å; E153-Y163 HydrophobicContact CG-CD1 4.43Å; E153-Y163 HydrophobicContact CG-CE1 3.95Å; E153-L166 HydrophobicContact CG-CD1 4.31Å
154K98.5Very high96Very high0 Ų016.8 Ų16.80%011%0.106CC..Hα-helixtrans-60.2-47.5172.9-171.2178.8173.9179.60112.7F20 V125 D126 R128 L129 A150 L151 L152 Y156 A157 K158 Y163F20-K154 HydrophobicContact CD1-CG 4.3Å; F20-K154 HydrophobicContact CE1-CG 4.05Å; V125-K154 HydrophobicContact CB-CD 4.26Å; V125-K154 HydrophobicContact CG1-CG 4.34Å; D126-K154 PolarHBondContact O-NZ 3.46Å; D126-K154 IonicContact OD1-NZ 2.72Å; D126-K154 PolarHBondContact OD1-NZ 2.99Å; D126-K154 IonicContact OD2-NZ 3.66Å; R128-K154 WeakPolarHBondContact O-CE 3.18Å; R128-K154 PolarHBondContact O-NZ 3.33Å; L129-K154 HydrophobicContact CD2-CB 4.41Å; L129-K154 HydrophobicContact CD2-CD 4.31Å; A150-K154 WeakPolarHBondContact O-CB 3.34Å; A150-K154 PolarHBondContact O-N 3.37Å; L151-K154 WeakPolarHBondContact O-CB 3.44Å; L151-K154 PolarHBondContact O-N 2.93Å; L152-K154 VanDerWaalsContact C-N 3.3Å; L152-K154 PolarHBondContact O-N 3.28Å; K154-Y156 VanDerWaalsContact C-N 3.27Å; K154-Y156 PolarHBondContact O-N 3.33Å; K154-A157 PolarHBondContact O-N 3.2Å; K154-K158 WeakPolarHBondContact O-CB 3.3Å; K154-K158 PolarHBondContact O-N 2.87Å; K154-Y163 WeakPolarHBondContact CA-OH 2.97Å; K154-Y163 WeakPolarHBondContact CB-OH 3.32Å; K154-Y163 HydrophobicContact CG-CE2 4.42Å; K154-Y163 WeakPolarHBondContact CG-OH 3.14Å
155A98.4Very high95.9Very high0 Ų013.4 Ų13.40%08%0.08CC..Hα-helixtrans-62.3-38.1178.400000111.5F112 I114 V123 V125 L151 L152 L159F112-A155 HydrophobicContact CB-CB 4.11Å; F112-A155 HydrophobicContact CD1-CB 4.44Å; F112-A155 HydrophobicContact CD2-CB 3.49Å; F112-A155 VanDerWaalsContact CD2-CB 3.49Å; F112-A155 HydrophobicContact CE2-CB 4.06Å; F112-A155 HydrophobicContact CG-CB 3.75Å; I114-A155 HydrophobicContact CD1-CB 4.29Å; V123-A155 HydrophobicContact CB-CB 4.38Å; V123-A155 HydrophobicContact CG1-CB 3.99Å; V125-A155 HydrophobicContact CG1-CB 4.08Å; V125-A155 HydrophobicContact CG2-CB 4.38Å; L151-A155 PolarHBondContact O-N 3.08Å; L152-A155 PolarHBondContact O-N 2.83Å; A155-L159 PolarHBondContact O-N 2.97Å; A155-L159 VanDerWaalsContact O-N 3.08Å
156Y97.9Very high95.8Very high0 Ų011.7 Ų11.70%07%0.068CC..Hα-helixtrans-68.3-43.4175.2-160.5-113.8000111.5W75 F76 I114 L152 E153 K154 K158 L159 H160 L166 D177W75-Y156 AromaticContact CH2-CE1 3.55Å; W75-Y156 HydrophobicContact CH2-CE1 3.55Å; W75-Y156 AromaticContact CH2-CZ 3.9Å; W75-Y156 VanDerWaalsContact CH2-OH 3.31Å; W75-Y156 WeakPolarHBondContact CH2-OH 3.42Å; W75-Y156 HydrophobicContact CZ2-CE1 4.01Å; W75-Y156 HydrophobicContact CZ3-CE1 4.24Å; W75-Y156 WeakPolarHBondContact CZ3-OH 3.48Å; F76-Y156 AromaticContact CD2-CD1 3.65Å; F76-Y156 HydrophobicContact CD2-CD1 3.65Å; F76-Y156 AromaticContact CD2-CE1 3.68Å; F76-Y156 HydrophobicContact CD2-CE1 3.68Å; F76-Y156 HydrophobicContact CD2-CG 4.08Å; F76-Y156 AromaticContact CE2-CD1 3.67Å; F76-Y156 HydrophobicContact CE2-CD1 3.67Å; F76-Y156 AromaticContact CE2-CD2 3.97Å; F76-Y156 HydrophobicContact CE2-CD2 3.97Å; F76-Y156 HydrophobicContact CE2-CE1 4.08Å; F76-Y156 HydrophobicContact CE2-CE2 4.37Å; F76-Y156 AromaticContact CE2-CG 3.61Å; F76-Y156 HydrophobicContact CE2-CG 3.61Å; F76-Y156 HydrophobicContact CG-CD1 4.22Å; F76-Y156 HydrophobicContact CG-CE1 4.35Å; F76-Y156 HydrophobicContact CZ-CD1 4.26Å; F76-Y156 HydrophobicContact CZ-CG 4.11Å; I114-Y156 HydrophobicContact CD1-CD2 4.18Å; I114-Y156 HydrophobicContact CG2-CD2 4.21Å; I114-Y156 HydrophobicContact CG2-CE2 4.27Å; L152-Y156 WeakPolarHBondContact O-CB 3.33Å; L152-Y156 PolarHBondContact O-N 3.45Å; E153-Y156 PolarHBondContact O-N 3.12Å; K154-Y156 VanDerWaalsContact C-N 3.27Å; K154-Y156 PolarHBondContact O-N 3.33Å; Y156-K158 PolarHBondContact O-N 2.66Å; Y156-L159 WeakPolarHBondContact O-CB 3.38Å; Y156-L159 PolarHBondContact O-N 2.94Å; Y156-L159 VanDerWaalsContact O-N 3.16Å; Y156-H160 AromaticContact CD1-CD2 3.82Å; Y156-H160 AromaticContact CE1-CD2 3.65Å; Y156-H160 AromaticContact CE1-NE2 3.56Å; Y156-H160 AromaticContact CE2-CD2 3.92Å; Y156-H160 AromaticContact CE2-NE2 3.44Å; Y156-H160 WeakPolarHBondContact CE2-NE2 3.5Å; Y156-H160 AromaticContact CZ-CD2 3.71Å; Y156-H160 AromaticContact CZ-NE2 3.16Å; Y156-H160 PolarHBondContact O-CD2 3.14Å; Y156-H160 PolarHBondContact O-N 2.77Å; Y156-H160 PolarHBondContact OH-NE2 3.21Å; Y156-L166 HydrophobicContact CD1-CD1 3.99Å; Y156-L166 HydrophobicContact CD1-CD2 3.43Å; Y156-L166 VanDerWaalsContact CD1-CD2 3.43Å; Y156-L166 HydrophobicContact CD1-CG 4.34Å; Y156-L166 HydrophobicContact CE1-CD2 3.76Å; Y156-L166 HydrophobicContact CG-CD2 4.42Å; Y156-D177 HydrophobicContact CE2-CB 4.03Å; Y156-D177 PolarHBondContact OH-OD2 3.42Å
157A97.3Very high95.4Very high0 Ų015.8 Ų15.80%08%0.083CC..Hα-helixtrans-58.7-44.8173.600000111.6F20 E153 K154 L159 H160 G161 S162 Y163 L166F20-A157 HydrophobicContact CZ-CB 4.02Å; E153-A157 WeakPolarHBondContact O-CB 3.32Å; E153-A157 PolarHBondContact O-N 3.43Å; K154-A157 PolarHBondContact O-N 3.2Å; A157-L159 VanDerWaalsContact C-N 3.32Å; A157-L159 PolarHBondContact O-N 3.42Å; A157-H160 CarbonylContact O-C 3.59Å; A157-H160 PolarHBondContact O-N 3.05Å; A157-G161 CarbonylContact O-C 3.57Å; A157-G161 PolarHBondContact O-N 3.32Å; A157-S162 PolarHBondContact O-N 3.05Å; A157-S162 VanDerWaalsContact O-N 3.14Å; A157-Y163 HydrophobicContact CB-CD1 3.86Å; A157-Y163 HydrophobicContact CB-CD2 4.04Å; A157-Y163 HydrophobicContact CB-CE1 4.12Å; A157-Y163 HydrophobicContact CB-CE2 4.29Å; A157-Y163 HydrophobicContact CB-CG 3.84Å; A157-L166 HydrophobicContact CB-CD1 3.83Å; A157-L166 HydrophobicContact CB-CG 4.32Å
158K97.1Very high94.7Very high42 Ų4219.1 Ų19.118%0.18311%0.111CC..Hα-helixtrans-56.5-45.1173.9174.6173.3-1781710112.1D17 F20 V123 T124 V125 K154 Y156 H160 G161D17-K158 IonicContact OD1-NZ 3.05Å; D17-K158 PolarHBondContact OD1-NZ 2.86Å; D17-K158 WeakPolarHBondContact OD2-CD 3.39Å; D17-K158 IonicContact OD2-NZ 2.77Å; D17-K158 PolarHBondContact OD2-NZ 3.18Å; F20-K158 HydrophobicContact CB-CB 4.15Å; F20-K158 HydrophobicContact CB-CD 3.71Å; F20-K158 HydrophobicContact CB-CG 3.83Å; F20-K158 HydrophobicContact CD1-CB 4.24Å; F20-K158 HydrophobicContact CD2-CB 3.7Å; F20-K158 HydrophobicContact CD2-CG 3.95Å; F20-K158 VanDerWaalsContact CE2-CA 3.49Å; F20-K158 HydrophobicContact CE2-CB 4.09Å; F20-K158 HydrophobicContact CG-CB 3.77Å; F20-K158 HydrophobicContact CG-CD 4.28Å; F20-K158 HydrophobicContact CG-CG 3.97Å; F20-K158 HydrophobicContact CZ-CB 4.49Å; V123-K158 HydrophobicContact CG1-CB 4.47Å; V123-K158 HydrophobicContact CG1-CD 3.94Å; V123-K158 HydrophobicContact CG1-CG 4.31Å; T124-K158 PolarHBondContact O-NZ 2.85Å; V125-K158 HydrophobicContact CG1-CB 4.36Å; V125-K158 HydrophobicContact CG1-CD 3.79Å; K154-K158 WeakPolarHBondContact O-CB 3.3Å; K154-K158 PolarHBondContact O-N 2.87Å; Y156-K158 PolarHBondContact O-N 2.66Å; K158-H160 VanDerWaalsContact C-N 3.29Å; K158-H160 PolarHBondContact O-N 2.65Å; K158-G161 PolarHBondContact O-N 3.1Å
159L94.3Very high94.3Very high49 Ų4920.2 Ų20.226%0.25712%0.122SC..Hα-helixtrans-64-35.2179.5-172.265000112.4I114 Q116 V123 A155 Y156 A157I114-L159 HydrophobicContact CB-CD2 3.97Å; I114-L159 HydrophobicContact CD1-CD2 4.15Å; I114-L159 HydrophobicContact CG2-CD2 3.56Å; Q116-L159 HydrophobicContact CG-CD1 4.21Å; Q116-L159 HydrophobicContact CG-CD2 3.69Å; Q116-L159 HydrophobicContact CG-CG 4.33Å; V123-L159 HydrophobicContact CG2-CD1 4.16Å; A155-L159 PolarHBondContact O-N 2.97Å; A155-L159 VanDerWaalsContact O-N 3.08Å; Y156-L159 WeakPolarHBondContact O-CB 3.38Å; Y156-L159 PolarHBondContact O-N 2.94Å; Y156-L159 VanDerWaalsContact O-N 3.16Å; A157-L159 VanDerWaalsContact C-N 3.32Å; A157-L159 PolarHBondContact O-N 3.42Å
160H90.8Very high93.9Very high48 Ų4824.1 Ų24.122%0.22214%0.14CC..Hα-helixtrans-90-10.7179.3-73.9-78.2000114.1Y156 A157 K158 Q165 L166Y156-H160 AromaticContact CD1-CD2 3.82Å; Y156-H160 AromaticContact CE1-CD2 3.65Å; Y156-H160 AromaticContact CE1-NE2 3.56Å; Y156-H160 AromaticContact CE2-CD2 3.92Å; Y156-H160 AromaticContact CE2-NE2 3.44Å; Y156-H160 WeakPolarHBondContact CE2-NE2 3.5Å; Y156-H160 AromaticContact CZ-CD2 3.71Å; Y156-H160 AromaticContact CZ-NE2 3.16Å; Y156-H160 PolarHBondContact O-CD2 3.14Å; Y156-H160 PolarHBondContact O-N 2.77Å; Y156-H160 PolarHBondContact OH-NE2 3.21Å; A157-H160 CarbonylContact O-C 3.59Å; A157-H160 PolarHBondContact O-N 3.05Å; K158-H160 VanDerWaalsContact C-N 3.29Å; K158-H160 PolarHBondContact O-N 2.65Å; H160-Q165 HydrophobicContact CB-CB 4.24Å; H160-L166 HydrophobicContact CB-CD2 3.84Å
161G92.8Very high93.6Very high44 Ų4424.4 Ų24.445%0.45414%0.142SC..SBendtrans112-33.9171.900000114.8A157 K158A157-G161 CarbonylContact O-C 3.57Å; A157-G161 PolarHBondContact O-N 3.32Å; K158-G161 PolarHBondContact O-N 3.1Å
162S94.6Very high93.4Very high2 Ų225.6 Ų25.61%0.01415%0.151CC..SBendtrans-160.7168.4174.769.90000110.7S26 A157 E164 Q165S26-S162 CarbonylContact O-C 3.52Å; S26-S162 VanDerWaalsContact O-CA 3.28Å; S26-S162 WeakPolarHBondContact O-CA 3.31Å; S26-S162 WeakPolarHBondContact O-CB 3.27Å; A157-S162 PolarHBondContact O-N 3.05Å; A157-S162 VanDerWaalsContact O-N 3.14Å; S162-E164 VanDerWaalsContact C-N 3.34Å; S162-Q165 PolarHBondContact O-N 3.37Å; S162-Q165 WeakPolarHBondContact OG-CG 3.33Å; S162-Q165 PolarHBondContact OG-N 3.12Å
163Y95.6Very high93.2Very high1 Ų126.6 Ų26.60%0.00416%0.155CC..SBendtrans-61.8-40.6172.7-82.3-85.6000112.2F20 S26 L27 W44 L71 P130 F138 E153 K154 A157 Q165 L166F20-Y163 HydrophobicContact CE1-CD2 4.35Å; F20-Y163 HydrophobicContact CE1-CE2 4.02Å; F20-Y163 HydrophobicContact CZ-CD2 4.16Å; F20-Y163 HydrophobicContact CZ-CE2 4.27Å; S26-Y163 WeakPolarHBondContact O-CD2 3.19Å; S26-Y163 PolarHBondContact O-N 3.37Å; L27-Y163 HydrophobicContact CD2-CD2 4.01Å; W44-Y163 HydrophobicContact CH2-CE2 4.11Å; L71-Y163 WeakPolarHBondContact CD1-O 3.33Å; L71-Y163 HydrophobicContact CD2-CD1 4.05Å; P130-Y163 HydrophobicContact CG-CD2 4.36Å; P130-Y163 HydrophobicContact CG-CE2 3.71Å; F138-Y163 HydrophobicContact CB-CE1 4.45Å; F138-Y163 AromaticContact CD2-CD1 3.33Å; F138-Y163 HydrophobicContact CD2-CD1 3.33Å; F138-Y163 HydrophobicContact CD2-CD2 4.26Å; F138-Y163 AromaticContact CD2-CE1 3.33Å; F138-Y163 HydrophobicContact CD2-CE1 3.33Å; F138-Y163 HydrophobicContact CD2-CE2 4.27Å; F138-Y163 AromaticContact CD2-CG 3.8Å; F138-Y163 HydrophobicContact CD2-CG 3.8Å; F138-Y163 AromaticContact CD2-CZ 3.81Å; F138-Y163 AromaticContact CE2-CD1 3.46Å; F138-Y163 HydrophobicContact CE2-CD1 3.46Å; F138-Y163 VanDerWaalsContact CE2-CD1 3.46Å; F138-Y163 AromaticContact CE2-CD2 3.75Å; F138-Y163 HydrophobicContact CE2-CD2 3.75Å; F138-Y163 AromaticContact CE2-CE1 3.84Å; F138-Y163 HydrophobicContact CE2-CE1 3.84Å; F138-Y163 HydrophobicContact CE2-CE2 4.1Å; F138-Y163 AromaticContact CE2-CG 3.39Å; F138-Y163 HydrophobicContact CE2-CG 3.39Å; F138-Y163 HydrophobicContact CG-CD1 4.11Å; F138-Y163 HydrophobicContact CG-CE1 4.19Å; F138-Y163 HydrophobicContact CZ-CD1 4.34Å; F138-Y163 HydrophobicContact CZ-CG 4.14Å; E153-Y163 HydrophobicContact CG-CD1 4.43Å; E153-Y163 HydrophobicContact CG-CE1 3.95Å; K154-Y163 WeakPolarHBondContact CA-OH 2.97Å; K154-Y163 WeakPolarHBondContact CB-OH 3.32Å; K154-Y163 HydrophobicContact CG-CE2 4.42Å; K154-Y163 WeakPolarHBondContact CG-OH 3.14Å; A157-Y163 HydrophobicContact CB-CD1 3.86Å; A157-Y163 HydrophobicContact CB-CD2 4.04Å; A157-Y163 HydrophobicContact CB-CE1 4.12Å; A157-Y163 HydrophobicContact CB-CE2 4.29Å; A157-Y163 HydrophobicContact CB-CG 3.84Å; Y163-Q165 PolarHBondContact O-N 3.22Å; Y163-L166 WeakPolarHBondContact O-CB 3.31Å; Y163-L166 PolarHBondContact O-N 3.5Å
164E92.2Very high93Very high5 Ų526.5 Ų26.52%0.02316%0.155CC..G310 helixtrans-56.2-33.9177.6-175.8167.5-133.400113.1L27 S29 D30 S31 S32 T33 I35 S162 L166 W167L27-E164 WeakPolarHBondContact O-CB 3.34Å; L27-E164 PolarHBondContact O-N 3.03Å; S29-E164 WeakPolarHBondContact CA-OE2 3.34Å; S29-E164 PolarHBondContact N-OE2 3.36Å; S29-E164 PolarHBondContact OG-OE2 3.33Å; D30-E164 PolarHBondContact N-OE2 2.96Å; D30-E164 VanDerWaalsContact N-OE2 3.09Å; S31-E164 WeakPolarHBondContact CA-OE1 3.26Å; S31-E164 PolarHBondContact N-OE1 3.32Å; S31-E164 PolarHBondContact N-OE2 3.23Å; S32-E164 PolarHBondContact N-OE1 2.97Å; S32-E164 VanDerWaalsContact N-OE1 3.09Å; T33-E164 WeakPolarHBondContact CB-OE1 3.4Å; T33-E164 HydrophobicContact CG2-CG 3.64Å; T33-E164 PolarHBondContact N-OE1 3.12Å; T33-E164 VanDerWaalsContact N-OE1 3.12Å; T33-E164 WeakPolarHBondContact OG1-CG 3.43Å; T33-E164 PolarHBondContact OG1-OE1 3.14Å; I35-E164 HydrophobicContact CD1-CB 3.91Å; I35-E164 HydrophobicContact CD1-CG 4.42Å; S162-E164 VanDerWaalsContact C-N 3.34Å; E164-L166 PolarHBondContact O-N 3.23Å; E164-L166 VanDerWaalsContact O-N 3.13Å; E164-W167 WeakPolarHBondContact O-CB 3.26Å; E164-W167 PolarHBondContact O-N 2.87Å
165Q89.8Confident93Very high44 Ų4426.7 Ų26.721%0.20616%0.156CC..G310 helixtrans-67.6-12179-67.5-75.616.100113.9H160 S162 Y163 W167H160-Q165 HydrophobicContact CB-CB 4.24Å; S162-Q165 PolarHBondContact O-N 3.37Å; S162-Q165 WeakPolarHBondContact OG-CG 3.33Å; S162-Q165 PolarHBondContact OG-N 3.12Å; Y163-Q165 PolarHBondContact O-N 3.22Å; Q165-W167 VanDerWaalsContact C-N 3.35Å
166L91.9Very high92.9Very high1 Ų127 Ų271%0.00516%0.157CC..G310 helixtrans-86.3-6.4174-53.7-172.5000113L71 D73 W75 E153 Y156 A157 H160 Y163 E164 A168L71-L166 HydrophobicContact CD2-CB 4.05Å; L71-L166 HydrophobicContact CD2-CD1 4.26Å; D73-L166 HydrophobicContact CB-CB 4.41Å; W75-L166 PolarHBondContact NE1-O 2.96Å; E153-L166 HydrophobicContact CG-CD1 4.31Å; Y156-L166 HydrophobicContact CD1-CD1 3.99Å; Y156-L166 HydrophobicContact CD1-CD2 3.43Å; Y156-L166 VanDerWaalsContact CD1-CD2 3.43Å; Y156-L166 HydrophobicContact CD1-CG 4.34Å; Y156-L166 HydrophobicContact CE1-CD2 3.76Å; Y156-L166 HydrophobicContact CG-CD2 4.42Å; A157-L166 HydrophobicContact CB-CD1 3.83Å; A157-L166 HydrophobicContact CB-CG 4.32Å; H160-L166 HydrophobicContact CB-CD2 3.84Å; Y163-L166 WeakPolarHBondContact O-CB 3.31Å; Y163-L166 PolarHBondContact O-N 3.5Å; E164-L166 PolarHBondContact O-N 3.23Å; E164-L166 VanDerWaalsContact O-N 3.13Å; L166-A168 PolarHBondContact O-N 3.02Å
167W88.6Confident92.8Very high89 Ų8927 Ų2734%0.33716%0.157SC..THydrogen-bonded Turntrans-64.1127.1178.8-172-83.4000111.3T33 P34 I35 L71 E164 Q165T33-W167 HydrophobicContact CG2-CB 3.69Å; T33-W167 HydrophobicContact CG2-CD2 3.96Å; T33-W167 HydrophobicContact CG2-CG 3.52Å; P34-W167 HydrophobicContact CB-CH2 4.12Å; P34-W167 VanDerWaalsContact CD-CZ2 3.47Å; P34-W167 HydrophobicContact CG-CH2 3.69Å; P34-W167 HydrophobicContact CG-CZ2 3.74Å; P34-W167 HydrophobicContact CG-CZ3 4.47Å; I35-W167 HydrophobicContact CG2-CE3 4.24Å; I35-W167 HydrophobicContact CG2-CZ3 3.92Å; L71-W167 HydrophobicContact CD1-CE3 4.15Å; E164-W167 WeakPolarHBondContact O-CB 3.26Å; E164-W167 PolarHBondContact O-N 2.87Å; Q165-W167 VanDerWaalsContact C-N 3.35Å
168A83.1Confident92.8Very high73 Ų7327 Ų2760%0.60316%0.158SC*.THydrogen-bonded Turntrans57.856172.100000115.8G72 L166G72-A168 PolarHBondContact O-N 2.91Å; L166-A168 PolarHBondContact O-N 3.02Å
169G86.2Confident92.8Very high23 Ų2325.4 Ų25.424%0.23715%0.151CC..  trans-91.7-165171.400000114.8W75W75-G169 VanDerWaalsContact CG-C 3.43Å; W75-G169 VanDerWaalsContact NE1-N 3.13Å
170Q88.6Confident92.8Very high81 Ų8123.8 Ų23.838%0.37915%0.147SC..  trans-122.1132.5-177.2-63.6-62-53.400111.4S172 E173 A174Q170-S172 PolarHBondContact O-N 2.78Å; Q170-S172 VanDerWaalsContact O-N 3.13Å; Q170-E173 HydrophobicContact CB-CG 4.09Å; Q170-E173 WeakPolarHBondContact O-CB 3.48Å; Q170-E173 PolarHBondContact O-N 3.43Å; Q170-A174 PolarHBondContact O-N 2.84Å
171V93.3Very high92.9Very high9 Ų921.6 Ų21.66%0.05514%0.136CC..Hα-helixtrans-55.6-37.3-176.6-179.20000111.8W75 C78 E173 A174 L175 A245 T322W75-V171 HydrophobicContact CB-CG2 4Å; C78-V171 HydrophobicContact CB-CG1 4.04Å; C78-V171 HydrophobicContact CB-CG2 4.13Å; V171-E173 VanDerWaalsContact C-N 3.25Å; V171-E173 PolarHBondContact O-N 3.41Å; V171-A174 PolarHBondContact O-N 2.83Å; V171-L175 HydrophobicContact CG1-CD1 3.86Å; V171-L175 HydrophobicContact CG1-CG 4.07Å; V171-L175 WeakPolarHBondContact O-CB 3.3Å; V171-L175 WeakPolarHBondContact O-CG 3.25Å; V171-L175 PolarHBondContact O-N 3.18Å; V171-A245 HydrophobicContact CG2-CB 3.6Å; V171-T322 HydrophobicContact CB-CG2 4.32Å; V171-T322 HydrophobicContact CG1-CG2 4.31Å
172S93.5Very high93.1Very high25 Ų2519.6 Ų19.618%0.17512%0.116CC..Hα-helixtrans-59-35.9177.953.40000112.5Q170 V176Q170-S172 PolarHBondContact O-N 2.78Å; Q170-S172 VanDerWaalsContact O-N 3.13Å; S172-V176 VanDerWaalsContact O-CG2 3.3Å; S172-V176 WeakPolarHBondContact O-CG2 3.27Å; S172-V176 PolarHBondContact O-N 2.65Å
173E93.5Very high93Very high20 Ų2019.7 Ų19.79%0.09312%0.117CC..Hα-helixtrans-69.5-46.8178.1-60.8-170.117600111.7W75 Q170 V171 L175 V176 D177 Y415 R451W75-E173 HydrophobicContact CZ3-CB 4.09Å; Q170-E173 HydrophobicContact CB-CG 4.09Å; Q170-E173 WeakPolarHBondContact O-CB 3.48Å; Q170-E173 PolarHBondContact O-N 3.43Å; V171-E173 VanDerWaalsContact C-N 3.25Å; V171-E173 PolarHBondContact O-N 3.41Å; E173-L175 VanDerWaalsContact C-N 3.33Å; E173-L175 PolarHBondContact O-N 3.49Å; E173-V176 PolarHBondContact O-N 2.86Å; E173-D177 WeakPolarHBondContact O-CB 3.49Å; E173-D177 PolarHBondContact O-N 2.92Å; E173-Y415 WeakPolarHBondContact OE1-CE2 3.4Å; E173-Y415 PolarHBondContact OE1-OH 2.81Å; E173-Y415 PolarHBondContact OE2-OH 3.23Å; E173-R451 HydrophobicContact CG-CB 4.16Å
174A95.8Very high92.7Very high0 Ų020.7 Ų20.70%012%0.121CC..Hα-helixtrans-65.3-38.1177.400000111.5W75 F76 A79 Q170 V171 D177 L178W75-A174 HydrophobicContact CE3-CB 3.55Å; W75-A174 HydrophobicContact CZ3-CB 3.57Å; F76-A174 HydrophobicContact CB-CB 4.44Å; F76-A174 HydrophobicContact CD2-CB 4.11Å; A79-A174 HydrophobicContact CB-CB 3.54Å; Q170-A174 PolarHBondContact O-N 2.84Å; V171-A174 PolarHBondContact O-N 2.83Å; A174-D177 PolarHBondContact O-N 2.86Å; A174-L178 WeakPolarHBondContact O-CB 3.41Å; A174-L178 WeakPolarHBondContact O-CG 3.44Å; A174-L178 PolarHBondContact O-N 2.75Å
175L96.6Very high92.4Very high5 Ų523 Ų233%0.02613%0.13CC..Hα-helixtrans-60.1-47.3173.5-75.8173.2000110.9A79 F82 V171 E173 D177 T179 A183 A225 T322A79-L175 HydrophobicContact CB-CD2 3.89Å; A79-L175 HydrophobicContact CB-CG 4.07Å; F82-L175 HydrophobicContact CB-CD2 4.15Å; F82-L175 HydrophobicContact CD1-CD2 4.07Å; F82-L175 HydrophobicContact CG-CD2 4.3Å; V171-L175 HydrophobicContact CG1-CD1 3.86Å; V171-L175 HydrophobicContact CG1-CG 4.07Å; V171-L175 WeakPolarHBondContact O-CB 3.3Å; V171-L175 WeakPolarHBondContact O-CG 3.25Å; V171-L175 PolarHBondContact O-N 3.18Å; E173-L175 VanDerWaalsContact C-N 3.33Å; E173-L175 PolarHBondContact O-N 3.49Å; L175-D177 VanDerWaalsContact C-N 3.35Å; L175-D177 PolarHBondContact O-N 3.46Å; L175-T179 VanDerWaalsContact O-CB 3.22Å; L175-T179 WeakPolarHBondContact O-CB 3.44Å; L175-T179 WeakPolarHBondContact O-CG2 3.47Å; L175-T179 PolarHBondContact O-N 2.87Å; L175-T179 PolarHBondContact O-OG1 3.33Å; L175-A183 HydrophobicContact CB-CB 4.24Å; L175-A183 HydrophobicContact CD1-CB 4.37Å; L175-A225 HydrophobicContact CD1-CB 4Å; L175-A225 HydrophobicContact CD2-CB 3.63Å; L175-T322 HydrophobicContact CD1-CG2 3.9Å
176V96.5Very high92.2Very high5 Ų521.3 Ų21.33%0.0312%0.122CC..Hα-helixtrans-63.5-41.7177.4171.40000111.2W115 S172 E173 T179 G180 A183 L388W115-V176 HydrophobicContact CE3-CG1 3.71Å; W115-V176 HydrophobicContact CH2-CG1 4.19Å; W115-V176 HydrophobicContact CZ3-CG1 3.45Å; W115-V176 VanDerWaalsContact CZ3-CG1 3.45Å; S172-V176 VanDerWaalsContact O-CG2 3.3Å; S172-V176 WeakPolarHBondContact O-CG2 3.27Å; S172-V176 PolarHBondContact O-N 2.65Å; E173-V176 PolarHBondContact O-N 2.86Å; V176-T179 PolarHBondContact O-N 2.88Å; V176-G180 VanDerWaalsContact O-CA 3.27Å; V176-G180 WeakPolarHBondContact O-CA 3.48Å; V176-G180 PolarHBondContact O-N 2.85Å; V176-A183 HydrophobicContact CG2-CB 4.13Å; V176-L388 HydrophobicContact CG1-CD1 3.98Å
177D97.1Very high91.6Very high0 Ų021.7 Ų21.70%012%0.124CC..Hα-helixtrans-71.2-32-177.7-71.8-0.4000113.1I114 W115 Q116 Y156 E173 A174 L175 R451I114-D177 HydrophobicContact CG2-CB 4.09Å; W115-D177 WeakPolarHBondContact CA-O 3.47Å; W115-D177 VanDerWaalsContact CB-O 3.31Å; W115-D177 WeakPolarHBondContact CB-O 3.33Å; W115-D177 PolarHBondContact N-O 3Å; W115-D177 WeakPolarHBondContact O-CA 3.23Å; Q116-D177 PolarHBondContact NE2-OD2 2.84Å; Y156-D177 HydrophobicContact CE2-CB 4.03Å; Y156-D177 PolarHBondContact OH-OD2 3.42Å; E173-D177 WeakPolarHBondContact O-CB 3.49Å; E173-D177 PolarHBondContact O-N 2.92Å; A174-D177 PolarHBondContact O-N 2.86Å; L175-D177 VanDerWaalsContact C-N 3.35Å; L175-D177 PolarHBondContact O-N 3.46Å; D177-R451 VanDerWaalsContact CG-NH1 3.31Å; D177-R451 IonicContact OD1-CZ 3.25Å; D177-R451 VanDerWaalsContact OD1-CZ 3.23Å; D177-R451 IonicContact OD1-NH1 3.97Å; D177-R451 PolarHBondContact OD1-NH1 2.68Å; D177-R451 IonicContact OD1-NH2 3.55Å; D177-R451 PolarHBondContact OD1-NH2 3.02Å; D177-R451 IonicContact OD2-NH1 2.73Å; D177-R451 PolarHBondContact OD2-NH1 2.79Å; D177-R451 IonicContact OD2-NH2 2.71Å
178L97.2Very high91Very high1 Ų118.2 Ų18.21%0.00511%0.112CC..Hα-helixtrans-88-15.8178.1-65.2-178.4000113.8F76 A79 V93 L152 A174F76-L178 HydrophobicContact CD2-CD1 4.49Å; F76-L178 HydrophobicContact CE2-CD1 4.08Å; F76-L178 HydrophobicContact CE2-CD2 4.31Å; F76-L178 HydrophobicContact CE2-CG 4.47Å; A79-L178 HydrophobicContact CB-CD1 3.87Å; V93-L178 HydrophobicContact CG1-CD2 4.41Å; V93-L178 VanDerWaalsContact CG2-O 3.31Å; V93-L178 WeakPolarHBondContact CG2-O 3.24Å; L152-L178 HydrophobicContact CD1-CD2 4.44Å; L152-L178 HydrophobicContact CD2-CD2 4.26Å; A174-L178 WeakPolarHBondContact O-CB 3.41Å; A174-L178 WeakPolarHBondContact O-CG 3.44Å; A174-L178 PolarHBondContact O-N 2.75Å
179T96Very high90.2Very high9 Ų919.2 Ų19.26%0.05510%0.1CC..Hα-helixtrans-116.6-25.6-174.871.70000113.3F82 L89 W120 L175 V176 G181 I327F82-T179 HydrophobicContact CD1-CG2 4.06Å; F82-T179 HydrophobicContact CE1-CG2 3.89Å; L89-T179 HydrophobicContact CD1-CG2 3.84Å; W120-T179 WeakPolarHBondContact CZ2-O 3.25Å; L175-T179 VanDerWaalsContact O-CB 3.22Å; L175-T179 WeakPolarHBondContact O-CB 3.44Å; L175-T179 WeakPolarHBondContact O-CG2 3.47Å; L175-T179 PolarHBondContact O-N 2.87Å; L175-T179 PolarHBondContact O-OG1 3.33Å; V176-T179 PolarHBondContact O-N 2.88Å; T179-G181 PolarHBondContact O-N 3.08Å; T179-G181 PolarHBondContact OG1-N 2.78Å; T179-I327 WeakPolarHBondContact O-CD1 3.33Å
180G94.1Very high88.5Confident15 Ų1524.9 Ų24.916%0.15512%0.121CC..SBendtrans66.84.1-166.300000114.2W115 V176 R482W115-G180 VanDerWaalsContact CG-CA 3.44Å; V176-G180 VanDerWaalsContact O-CA 3.27Å; V176-G180 WeakPolarHBondContact O-CA 3.48Å; V176-G180 PolarHBondContact O-N 2.85Å; G180-R482 PolarHBondContact O-NH1 2.97Å
181G94.5Very high86.2Confident1 Ų128.8 Ų28.81%0.0114%0.137CC..SBendtrans-84.3-149.1-17900000112.9T179 R482T179-G181 PolarHBondContact O-N 3.08Å; T179-G181 PolarHBondContact OG1-N 2.78Å; G181-R482 VanDerWaalsContact O-CZ 3.31Å; G181-R482 PolarHBondContact O-NH1 2.94Å; G181-R482 PolarHBondContact O-NH2 2.72Å
182V95.3Very high83.6Confident3 Ų330.7 Ų30.72%0.01816%0.158CC..  trans-125143.3-178.3178.50000108.7Y325 L333 L384 V454 F484V182-Y325 HydrophobicContact CB-CD2 4.02Å; V182-Y325 HydrophobicContact CB-CG 4.21Å; V182-Y325 HydrophobicContact CG1-CD2 4.03Å; V182-Y325 HydrophobicContact CG1-CE2 4.07Å; V182-Y325 WeakPolarHBondContact O-CB 3.3Å; V182-Y325 WeakPolarHBondContact O-CD2 3.46Å; V182-Y325 PolarHBondContact O-N 3.38Å; V182-L333 HydrophobicContact CB-CD2 4.16Å; V182-L333 HydrophobicContact CG2-CD2 3.76Å; V182-L384 HydrophobicContact CG1-CD2 4.36Å; V182-L384 HydrophobicContact CG2-CD2 3.99Å; V182-V454 HydrophobicContact CG1-CB 4.46Å; V182-V454 HydrophobicContact CG1-CG1 4.13Å; V182-V454 HydrophobicContact CG1-CG2 3.45Å; V182-V454 VanDerWaalsContact CG1-CG2 3.45Å; V182-F484 HydrophobicContact CG2-CD2 4.16Å; V182-F484 HydrophobicContact CG2-CE2 3.58Å; V182-F484 HydrophobicContact CG2-CZ 4.14Å
183A94.1Very high80.8Confident4 Ų433.4 Ų33.43%0.03318%0.177CC..EExtended strand (participates in β ladder)trans-131.5145.4171.400000110.7L175 V176 T322 V323L175-A183 HydrophobicContact CB-CB 4.24Å; L175-A183 HydrophobicContact CD1-CB 4.37Å; V176-A183 HydrophobicContact CG2-CB 4.13Å; A183-T322 HydrophobicContact CB-CG2 4.41Å; A183-V323 CarbonylContact C-O 3.24Å; A183-V323 VanDerWaalsContact CA-O 3.25Å; A183-V323 WeakPolarHBondContact CA-O 3.33Å
184E89.1Confident78.1Confident21 Ų2138.1 Ų38.110%0.09820%0.203CC..EExtended strand (participates in β ladder)trans-126.9148.6178.3-73.4-178.2-149.500110.9W186 T322 V323 Y325 Y337 V454E184-W186 PolarHBondContact OE2-NE1 2.8Å; E184-T322 CarbonylContact O-C 3.37Å; E184-T322 WeakPolarHBondContact O-CA 3.12Å; E184-V323 PolarHBondContact N-O 3.14Å; E184-V323 PolarHBondContact O-N 3.01Å; E184-Y325 HydrophobicContact CG-CE2 3.97Å; E184-Y325 WeakPolarHBondContact OE1-CE2 3.37Å; E184-Y325 VanDerWaalsContact OE1-CZ 3.31Å; E184-Y325 PolarHBondContact OE1-OH 2.84Å; E184-Y337 PolarHBondContact OE2-OH 2.59Å; E184-V454 HydrophobicContact CG-CB 3.82Å; E184-V454 HydrophobicContact CG-CG1 4.34Å; E184-V454 HydrophobicContact CG-CG2 3.7Å; E184-V454 WeakPolarHBondContact OE1-CB 3.11Å; E184-V454 WeakPolarHBondContact OE1-CG1 3.23Å
185R86.2Confident75.3Confident53 Ų5347.2 Ų47.220%0.224%0.242CC..EExtended strand (participates in β ladder)trans-106.3129173-170.7-172.4-173.8117.310.8110.5H231 D320 I321R185-H231 PolarHBondContact NH2-CE1 3.39Å; R185-H231 PolarHBondContact NH2-NE2 2.99Å; R185-H231 VanDerWaalsContact NH2-NE2 3.16Å; R185-D320 HydrophobicContact CG-CB 4.1Å; R185-D320 IonicContact CZ-OD2 3.91Å; R185-D320 IonicContact NE-OD1 3.23Å; R185-D320 PolarHBondContact NE-OD1 3.38Å; R185-D320 IonicContact NE-OD2 3.26Å; R185-D320 PolarHBondContact NE-OD2 2.88Å; R185-D320 IonicContact NH2-OD2 3.34Å; R185-D320 PolarHBondContact NH2-OD2 3.45Å; R185-I321 CarbonylContact C-O 2.97Å; R185-I321 VanDerWaalsContact CA-O 3.29Å; R185-I321 WeakPolarHBondContact CA-O 3.49Å
186W84.3Confident72.4Confident10 Ų1053.8 Ų53.84%0.03827%0.273CS..EExtended strand (participates in β ladder)trans-116.4142.9178-58.9-6.9000109.8E184 L212 L217 D320 I321 V323 V336 Y337E184-W186 PolarHBondContact OE2-NE1 2.8Å; W186-L212 HydrophobicContact CE3-CD1 3.52Å; W186-L212 HydrophobicContact CZ3-CD1 3.86Å; W186-L217 HydrophobicContact CH2-CD1 4.2Å; W186-L217 HydrophobicContact CH2-CD2 3.6Å; W186-L217 HydrophobicContact CH2-CG 3.91Å; W186-L217 HydrophobicContact CZ2-CD2 4.48Å; W186-L217 HydrophobicContact CZ3-CD1 3.92Å; W186-L217 HydrophobicContact CZ3-CD2 4.16Å; W186-L217 HydrophobicContact CZ3-CG 3.97Å; W186-D320 CarbonylContact O-C 3.54Å; W186-D320 VanDerWaalsContact O-CA 3.3Å; W186-D320 WeakPolarHBondContact O-CA 3.48Å; W186-I321 PolarHBondContact N-O 2.85Å; W186-I321 PolarHBondContact O-N 3.33Å; W186-V323 HydrophobicContact CD2-CG2 3.78Å; W186-V323 HydrophobicContact CE3-CG2 3.9Å; W186-V323 HydrophobicContact CG-CG2 4.37Å; W186-V323 HydrophobicContact CH2-CG2 4.19Å; W186-V323 HydrophobicContact CZ2-CG2 4.06Å; W186-V323 HydrophobicContact CZ3-CG2 4.1Å; W186-V336 HydrophobicContact CZ2-CG2 4.36Å; W186-Y337 HydrophobicContact CZ2-CE1 4.21Å
187S79.9Confident69.7Low9 Ų959.3 Ų59.36%0.06330%0.298CS..EExtended strand (participates in β ladder)trans-93.5137.8-177.9-174.50000110.6R189S187-R189 PolarHBondContact OG-O 3.28Å
188L75.4Confident66.6Low16 Ų1670.3 Ų70.38%0.08434%0.34CS..  trans-97-28.5176.7-62.8173.9000113.2L212 F314 F318 D319 I321L188-L212 HydrophobicContact CD2-CB 3.45Å; L188-L212 VanDerWaalsContact CD2-CB 3.45Å; L188-L212 HydrophobicContact CD2-CD2 3.41Å; L188-L212 VanDerWaalsContact CD2-CD2 3.41Å; L188-L212 HydrophobicContact CD2-CG 3.96Å; L188-F314 HydrophobicContact CD1-CE1 4.42Å; L188-F318 WeakPolarHBondContact CB-O 3.37Å; L188-F318 HydrophobicContact CD1-CB 3.5Å; L188-F318 WeakPolarHBondContact CD1-O 3.23Å; L188-D319 WeakPolarHBondContact CB-O 3.48Å; L188-D319 PolarHBondContact N-O 3.22Å; L188-I321 HydrophobicContact CD1-CD1 4.01Å; L188-I321 HydrophobicContact CD1-CG1 3.84Å; L188-I321 HydrophobicContact CD2-CD1 3.61Å; L188-I321 HydrophobicContact CD2-CG1 4.1Å; L188-I321 HydrophobicContact CG-CD1 4.18Å; L188-I321 HydrophobicContact CG-CG1 4.14Å
189R66.4Low63.4Low94 Ų9479.2 Ų79.236%0.35538%0.381SS..SBendtrans-85.4138.4-179.7-64.8-171.6176170.1-2.9112S187 D319S187-R189 PolarHBondContact OG-O 3.28Å; R189-D319 WeakPolarHBondContact CD-OD1 3.21Å; R189-D319 VanDerWaalsContact CZ-CG 3.46Å; R189-D319 IonicContact CZ-OD1 3.64Å; R189-D319 IonicContact CZ-OD2 2.82Å; R189-D319 IonicContact NE-OD1 3.64Å; R189-D319 PolarHBondContact NE-OD1 3.41Å; R189-D319 IonicContact NH1-OD1 3.88Å; R189-D319 PolarHBondContact NH1-OD1 3Å; R189-D319 IonicContact NH1-OD2 3.91Å; R189-D319 IonicContact NH2-OD1 2.7Å; R189-D319 IonicContact NH2-OD2 3.26Å
190E51.5Low60.4Low142 Ų14282 Ų8266%0.66441%0.406SS*.  trans-74.5125.3171.4-68.7-178.816800109.1K211E190-K211 IonicContact OE1-NZ 3.4Å; E190-K211 PolarHBondContact OE1-NZ 3.05Å
191F39.5Very low57.7Low163 Ų16387.2 Ų87.272%0.71543%0.434SS*.  trans-90.4110167.5-76.6-86.3000107.9
192G39.9Very low54.8Low48 Ų4895.2 Ų95.250%0.49548%0.476SS..SBendtrans115.8121.5170.100000113.6
193S33Very low51.7Low83 Ų83102 Ų10258%0.5851%0.512SS*.  trans-71.9143.1169.155.90000111.1K195 E196S193-K195 PolarHBondContact O-N 3.24Å; S193-E196 PolarHBondContact O-N 3.4Å; S193-E196 VanDerWaalsContact O-N 3.12Å
194D38.4Very low49Very low118 Ų118106.4 Ų106.463%0.63154%0.543SS*.THydrogen-bonded Turntrans-44.9-7.9177.7-57.9-15.3000117.4
195K35.7Very low46.5Very low191 Ų191112.8 Ų112.883%0.8358%0.577SS**THydrogen-bonded Turntrans-79.7-22.4175.5-74.4-171.5176.3-179.50114.3S193S193-K195 PolarHBondContact O-N 3.24Å
196E35.8Very low44.1Very low143 Ų143118.5 Ų118.567%0.66861%0.606SS**SBendtrans-89.3-10.1175.3-72.8176.2162.800112.7S193 R198S193-E196 PolarHBondContact O-N 3.4Å; S193-E196 VanDerWaalsContact O-N 3.12Å; E196-R198 VanDerWaalsContact C-N 3.25Å; E196-R198 PolarHBondContact O-N 3.37Å
197E39.5Very low41.9Very low122 Ų122123 Ų12357%0.5763%0.634SS**THydrogen-bonded Turntrans-68.2-17.9-178.8-75.6-164.2132.600114.5
198R31.8Very low39.8Very low230 Ų230132 Ų13287%0.86867%0.667SS**THydrogen-bonded Turntrans-95.4-10.4-174-72.7-173.6175.6-161.5-1.2115.4E196E196-R198 VanDerWaalsContact C-N 3.25Å; E196-R198 PolarHBondContact O-N 3.37Å
199E31.8Very low38.5Very low188 Ų188136.9 Ų136.988%0.87968%0.684SS**THydrogen-bonded Turntrans-111.5-7.3179.3-68.7-171163.600114.1V201E199-V201 PolarHBondContact O-N 2.82Å
200A31.7Very low37.8Very low68 Ų68136.2 Ų136.256%0.56268%0.684SS**  trans-96.243-175.800000114.9
201V37.2Very low38.3Very low124 Ų124136.6 Ų136.675%0.75268%0.683SS**SBendtrans-94.9-1.1176.4178.30000113.1E199E199-V201 PolarHBondContact O-N 2.82Å
202L33.9Very low39.4Very low170 Ų170129.8 Ų129.889%0.8966%0.655SS**SBendtrans-141.650-175.2-69.2169.2000113.7
203D29.8Very low40.9Very low146 Ų146130.5 Ų130.578%0.78165%0.647SS**  trans-160.2147.9145.4-146.2-14.4000111.7
204S38.3Very low43Very low96 Ų96126.7 Ų126.767%0.67162%0.62SS**SBendtrans-58.5149179.455.70000114.4
205D37.2Very low45Very low154 Ų154125 Ų12582%0.82461%0.611SS**  trans8028.6149.8-117.317.2000120.4V207D205-V207 PolarHBondContact O-N 3.42Å
206Q34.6Very low47Very low174 Ų174119.6 Ų119.681%0.81359%0.591SS**  trans-87.6103167.4-70.1-166.814.500113.8R208Q206-R208 PolarHBondContact O-N 3.08Å
207V38.2Very low49.3Very low104 Ų104112.8 Ų112.863%0.6356%0.559SS**  trans15.296.2147.7-168.30000116.6D205D205-V207 PolarHBondContact O-N 3.42Å
208R36.8Very low51.4Low197 Ų197110.2 Ų110.274%0.74355%0.554SS**  trans-118.2104.8152.2-74.2-175.6174.6-174.7-4.1108.8Q206Q206-R208 PolarHBondContact O-N 3.08Å
209R47.2Very low53.9Low119 Ų119102.3 Ų102.345%0.44953%0.533SS..PPolyproline II helixtrans-59.8139158.8-75.3-175.3176.4160.6-3107K211R209-K211 PolarHBondContact O-N 2.76Å; R209-K211 VanDerWaalsContact O-N 3.17Å
210K52.6Low56.5Low80 Ų8093.4 Ų93.435%0.34849%0.492SS..PPolyproline II helixtrans-55.8122.9178.4-75.5-179.4-179.6178.60109.1Y337K210-Y337 VanDerWaalsContact NZ-CZ 3.34Å; K210-Y337 PolarHBondContact NZ-OH 2.89Å
211K61.7Low59.1Low150 Ų15092.5 Ų92.565%0.65248%0.475SS*.BIsolated β-bridgetrans-59.9133.6170.3-176.1165.8-176.4154.50108.1E190 R209 D213E190-K211 IonicContact OE1-NZ 3.4Å; E190-K211 PolarHBondContact OE1-NZ 3.05Å; R209-K211 PolarHBondContact O-N 2.76Å; R209-K211 VanDerWaalsContact O-N 3.17Å; K211-D213 PolarHBondContact O-N 3.2Å
212L62.6Low61.4Low21 Ų2193.5 Ų93.511%0.1147%0.471CS..PPolyproline II helixtrans-57.5125.5170.4177.875.4000108.5W186 L188 L214 F314 I321W186-L212 HydrophobicContact CE3-CD1 3.52Å; W186-L212 HydrophobicContact CZ3-CD1 3.86Å; L188-L212 HydrophobicContact CD2-CB 3.45Å; L188-L212 VanDerWaalsContact CD2-CB 3.45Å; L188-L212 HydrophobicContact CD2-CD2 3.41Å; L188-L212 VanDerWaalsContact CD2-CD2 3.41Å; L188-L212 HydrophobicContact CD2-CG 3.96Å; L212-L214 HydrophobicContact CD1-CD2 3.97Å; L212-L214 HydrophobicContact CD1-CG 4.35Å; L212-L214 HydrophobicContact CD2-CD1 4.32Å; L212-L214 HydrophobicContact CD2-CD2 3.96Å; L212-L214 HydrophobicContact CD2-CG 3.75Å; L212-L214 HydrophobicContact CG-CD2 4.3Å; L212-L214 HydrophobicContact CG-CG 4.16Å; L212-F314 HydrophobicContact CD2-CD1 4.48Å; L212-F314 HydrophobicContact CD2-CE1 4.04Å; L212-I321 HydrophobicContact CD1-CD1 3.71Å; L212-I321 HydrophobicContact CD2-CD1 3.4Å; L212-I321 VanDerWaalsContact CD2-CD1 3.4Å; L212-I321 HydrophobicContact CG-CD1 4.06Å
213D70.6Confident64Low63 Ų6389.1 Ų89.134%0.33745%0.446SS..  trans-126.8102.4160.31786000106.8K211 N215 L216K211-D213 PolarHBondContact O-N 3.2Å; D213-N215 PolarHBondContact O-N 2.78Å; D213-N215 VanDerWaalsContact O-N 3.08Å; D213-N215 WeakPolarHBondContact OD1-CB 3.47Å; D213-N215 VanDerWaalsContact OD1-CG 3.26Å; D213-N215 PolarHBondContact OD1-N 3.27Å; D213-N215 PolarHBondContact OD1-ND2 2.87Å; D213-L216 HydrophobicContact CB-CD1 3.9Å; D213-L216 HydrophobicContact CB-CG 3.86Å; D213-L216 VanDerWaalsContact O-CB 3.27Å; D213-L216 WeakPolarHBondContact O-CB 3.36Å; D213-L216 PolarHBondContact O-N 2.93Å
214L77.8Confident66.9Low2 Ų282.7 Ų82.71%0.0141%0.413CS..G310 helixtrans-58.3-20.6178.4-71.8172.5000111.7L212 L216 L217 L265L212-L214 HydrophobicContact CD1-CD2 3.97Å; L212-L214 HydrophobicContact CD1-CG 4.35Å; L212-L214 HydrophobicContact CD2-CD1 4.32Å; L212-L214 HydrophobicContact CD2-CD2 3.96Å; L212-L214 HydrophobicContact CD2-CG 3.75Å; L212-L214 HydrophobicContact CG-CD2 4.3Å; L212-L214 HydrophobicContact CG-CG 4.16Å; L214-L216 PolarHBondContact O-N 2.89Å; L214-L217 HydrophobicContact CD2-CD1 4.44Å; L214-L217 PolarHBondContact O-N 2.83Å; L214-L217 VanDerWaalsContact O-N 3.12Å; L214-L265 HydrophobicContact CD1-CD2 3.98Å
215N79.5Confident69.5Low84 Ų8478.4 Ų78.445%0.44938%0.383SS..G310 helixtrans-66.8-27.3175-54.6-53.7000112.3D213 L217 C218 R263D213-N215 PolarHBondContact O-N 2.78Å; D213-N215 VanDerWaalsContact O-N 3.08Å; D213-N215 WeakPolarHBondContact OD1-CB 3.47Å; D213-N215 VanDerWaalsContact OD1-CG 3.26Å; D213-N215 PolarHBondContact OD1-N 3.27Å; D213-N215 PolarHBondContact OD1-ND2 2.87Å; N215-L217 PolarHBondContact O-N 2.74Å; N215-C218 WeakPolarHBondContact O-CB 3.44Å; N215-C218 PolarHBondContact O-N 2.95Å; N215-R263 PolarHBondContact OD1-NH1 2.72Å; N215-R263 PolarHBondContact OD1-NH2 3.27Å
216L78.6Confident72.2Confident77 Ų7771.5 Ų71.540%0.40335%0.346SS..G310 helixtrans-63.6-29.2174-61.8174.7000111.6D213 L214D213-L216 HydrophobicContact CB-CD1 3.9Å; D213-L216 HydrophobicContact CB-CG 3.86Å; D213-L216 VanDerWaalsContact O-CB 3.27Å; D213-L216 WeakPolarHBondContact O-CB 3.36Å; D213-L216 PolarHBondContact O-N 2.93Å; L214-L216 PolarHBondContact O-N 2.89Å
217L84.9Confident75Confident0 Ų063.3 Ų63.30%031%0.308CS..G310 helixtrans-89.8-2.2-179.2-62178.5000113.4W186 L214 N215 C219 V220 K221 L226 W251 V323 V336W186-L217 HydrophobicContact CH2-CD1 4.2Å; W186-L217 HydrophobicContact CH2-CD2 3.6Å; W186-L217 HydrophobicContact CH2-CG 3.91Å; W186-L217 HydrophobicContact CZ2-CD2 4.48Å; W186-L217 HydrophobicContact CZ3-CD1 3.92Å; W186-L217 HydrophobicContact CZ3-CD2 4.16Å; W186-L217 HydrophobicContact CZ3-CG 3.97Å; L214-L217 HydrophobicContact CD2-CD1 4.44Å; L214-L217 PolarHBondContact O-N 2.83Å; L214-L217 VanDerWaalsContact O-N 3.12Å; N215-L217 PolarHBondContact O-N 2.74Å; L217-C219 PolarHBondContact O-N 3.09Å; L217-C219 VanDerWaalsContact O-N 3.13Å; L217-V220 HydrophobicContact CB-CG2 4.42Å; L217-V220 HydrophobicContact CD2-CG2 4.13Å; L217-V220 CarbonylContact O-C 3.58Å; L217-V220 WeakPolarHBondContact O-CG2 3.31Å; L217-V220 PolarHBondContact O-N 2.91Å; L217-K221 WeakPolarHBondContact O-CA 3.29Å; L217-K221 PolarHBondContact O-N 2.68Å; L217-L226 HydrophobicContact CD1-CD1 4.09Å; L217-L226 HydrophobicContact CD1-CD2 3.76Å; L217-L226 HydrophobicContact CD1-CG 4.44Å; L217-W251 HydrophobicContact CB-CZ2 4.15Å; L217-V323 HydrophobicContact CD1-CG1 4.38Å; L217-V323 HydrophobicContact CD1-CG2 4.34Å; L217-V323 HydrophobicContact CD2-CG1 4.01Å; L217-V336 HydrophobicContact CD2-CB 3.81Å; L217-V336 HydrophobicContact CD2-CG2 4.45Å
218C81.9Confident77.5Confident68 Ų6858.4 Ų58.446%0.45928%0.278SS..G310 helixtrans-55.5-35-177.5-80.50000113.1N215 V220N215-C218 WeakPolarHBondContact O-CB 3.44Å; N215-C218 PolarHBondContact O-N 2.95Å; C218-V220 PolarHBondContact O-N 3.47Å
219C84.6Confident79.9Confident63 Ų6349.9 Ų49.943%0.42625%0.249SC..G310 helixtrans-68.8-20.1179.163.10000114L217 G339L217-C219 PolarHBondContact O-N 3.09Å; L217-C219 VanDerWaalsContact O-N 3.13Å; C219-G339 PolarHBondContact SG-N 3.06Å
220V86.9Confident81.3Confident2 Ų245 Ų451%0.01223%0.232CC..G310 helixtrans-126.215-176.9-66.90000112.9L217 C218 E222 E223 C224 P326 S335 V336L217-V220 HydrophobicContact CB-CG2 4.42Å; L217-V220 HydrophobicContact CD2-CG2 4.13Å; L217-V220 CarbonylContact O-C 3.58Å; L217-V220 WeakPolarHBondContact O-CG2 3.31Å; L217-V220 PolarHBondContact O-N 2.91Å; C218-V220 PolarHBondContact O-N 3.47Å; V220-E222 VanDerWaalsContact C-N 3.3Å; V220-E222 PolarHBondContact O-N 2.81Å; V220-E222 VanDerWaalsContact O-N 3.16Å; V220-E223 PolarHBondContact O-N 2.87Å; V220-C224 HydrophobicContact CB-CB 4.32Å; V220-C224 HydrophobicContact CG2-CB 3.98Å; V220-C224 PolarHBondContact O-N 2.86Å; V220-C224 PolarHBondContact O-SG 2.76Å; V220-P326 HydrophobicContact CB-CG 3.76Å; V220-P326 HydrophobicContact CG1-CG 3.87Å; V220-P326 HydrophobicContact CG2-CG 4.48Å; V220-S335 WeakPolarHBondContact CG1-O 3.44Å; V220-V336 HydrophobicContact CG2-CB 4.24Å; V220-V336 HydrophobicContact CG2-CG1 4.42Å
221K86.1Confident81.7Confident48 Ų4844.1 Ų44.121%0.20923%0.229CC..THydrogen-bonded Turntrans-51.6-44-167.8162.5176.2177.3-168.60114.7L217 E223 W251L217-K221 WeakPolarHBondContact O-CA 3.29Å; L217-K221 PolarHBondContact O-N 2.68Å; K221-E223 VanDerWaalsContact C-N 3.33Å; K221-W251 VanDerWaalsContact CA-CH2 3.46Å; K221-W251 HydrophobicContact CB-CH2 3.76Å; K221-W251 HydrophobicContact CB-CZ2 3.49Å; K221-W251 VanDerWaalsContact CB-CZ2 3.49Å; K221-W251 HydrophobicContact CD-CD2 4.29Å; K221-W251 HydrophobicContact CD-CZ2 3.98Å; K221-W251 WeakPolarHBondContact CE-O 3.3Å; K221-W251 HydrophobicContact CG-CD2 4.13Å; K221-W251 HydrophobicContact CG-CE3 4.28Å; K221-W251 HydrophobicContact CG-CH2 3.58Å; K221-W251 HydrophobicContact CG-CZ2 3.38Å; K221-W251 HydrophobicContact CG-CZ3 3.99Å; K221-W251 PolarHBondContact NZ-O 2.93Å; K221-W251 WeakPolarHBondContact O-CH2 3.41Å; K221-W251 WeakPolarHBondContact O-CZ3 3.39Å
222E86Confident81.2Confident146 Ų14640 Ų4068%0.68222%0.219SC*.THydrogen-bonded Turntrans-85-10.4-177.3-57.9-59.2148.300112.7V220V220-E222 VanDerWaalsContact C-N 3.3Å; V220-E222 PolarHBondContact O-N 2.81Å; V220-E222 VanDerWaalsContact O-N 3.16Å
223E88.6Confident80.4Confident77 Ų7741.1 Ų41.136%0.3623%0.227SC..THydrogen-bonded Turntrans-113.7-23.4-170.9-52.3-172.5-112.900113.7F82 V220 K221 P326 K334F82-E223 WeakPolarHBondContact CE2-O 3.37Å; V220-E223 PolarHBondContact O-N 2.87Å; K221-E223 VanDerWaalsContact C-N 3.33Å; E223-P326 HydrophobicContact CB-CB 3.69Å; E223-P326 HydrophobicContact CB-CG 3.96Å; E223-K334 IonicContact OE1-NZ 3.73Å; E223-K334 PolarHBondContact OE1-NZ 3.29Å; E223-K334 IonicContact OE2-NZ 3.78Å; E223-K334 PolarHBondContact OE2-NZ 3.44Å
224C90.6Very high78.9Confident12 Ų1241.4 Ų41.48%0.08123%0.233CC..SBendtrans-81.6152.4-178.969.50000112V220 P326V220-C224 HydrophobicContact CB-CB 4.32Å; V220-C224 HydrophobicContact CG2-CB 3.98Å; V220-C224 PolarHBondContact O-N 2.86Å; V220-C224 PolarHBondContact O-SG 2.76Å; C224-P326 HydrophobicContact CB-CG 3.96Å
225A93.1Very high77.1Confident5 Ų544.4 Ų44.44%0.04126%0.264CS..EExtended strand (participates in β ladder)trans-87.7130.2171.600000109.1F82 L175 V323 G324F82-A225 HydrophobicContact CB-CB 4.03Å; F82-A225 HydrophobicContact CD1-CB 3.96Å; F82-A225 HydrophobicContact CD2-CB 3.4Å; F82-A225 VanDerWaalsContact CD2-CB 3.4Å; F82-A225 HydrophobicContact CE1-CB 4.26Å; F82-A225 HydrophobicContact CE2-CB 3.74Å; F82-A225 HydrophobicContact CG-CB 3.51Å; F82-A225 HydrophobicContact CZ-CB 4.15Å; L175-A225 HydrophobicContact CD1-CB 4Å; L175-A225 HydrophobicContact CD2-CB 3.63Å; A225-V323 CarbonylContact O-C 3.59Å; A225-V323 WeakPolarHBondContact O-CA 3.49Å; A225-G324 PolarHBondContact N-O 3.24Å; A225-G324 PolarHBondContact O-N 2.79Å
226L93.5Very high75.1Confident9 Ų944.6 Ų44.65%0.04729%0.285CS..EExtended strand (participates in β ladder)trans-128.2131.2175.4-73.8-178.8000111.4L217 V248 W251 I321 T322 V323L217-L226 HydrophobicContact CD1-CD1 4.09Å; L217-L226 HydrophobicContact CD1-CD2 3.76Å; L217-L226 HydrophobicContact CD1-CG 4.44Å; L226-V248 HydrophobicContact CB-CB 3.69Å; L226-V248 HydrophobicContact CB-CG1 4.47Å; L226-V248 HydrophobicContact CB-CG2 4.01Å; L226-V248 HydrophobicContact CD1-CG1 4.47Å; L226-V248 PolarHBondContact O-N 3.13Å; L226-W251 HydrophobicContact CD1-CE3 4Å; L226-W251 HydrophobicContact CD1-CH2 3.45Å; L226-W251 VanDerWaalsContact CD1-CH2 3.45Å; L226-W251 HydrophobicContact CD1-CZ2 4.34Å; L226-W251 HydrophobicContact CD1-CZ3 3.29Å; L226-W251 HydrophobicContact CG-CZ3 4.43Å; L226-I321 HydrophobicContact CD2-CG2 3.86Å; L226-T322 WeakPolarHBondContact CA-O 3.43Å; L226-V323 HydrophobicContact CD2-CB 4.12Å; L226-V323 HydrophobicContact CD2-CG1 3.99Å; L226-V323 HydrophobicContact CD2-CG2 3.66Å
227S93.4Very high73.2Confident3 Ų344.9 Ų44.92%0.02129%0.287CS..EExtended strand (participates in β ladder)trans-137145.1173.5175.20000110.1L246 I321 T322S227-L246 CarbonylContact C-O 3.59Å; S227-L246 WeakPolarHBondContact CA-O 3.44Å; S227-L246 VanDerWaalsContact CB-O 3.27Å; S227-L246 WeakPolarHBondContact CB-O 3.33Å; S227-L246 PolarHBondContact OG-O 2.77Å; S227-I321 CarbonylContact O-C 3.5Å; S227-I321 WeakPolarHBondContact O-CA 3.32Å; S227-T322 PolarHBondContact N-O 2.89Å; S227-T322 PolarHBondContact O-N 2.79Å
228C90.9Very high71Confident0 Ų047.1 Ų47.10%031%0.31CS..EExtended strand (participates in β ladder)trans-118.1155.8173.958.20000110.7L246 F314 F318 D320 I321C228-L246 PolarHBondContact N-O 2.85Å; C228-L246 PolarHBondContact O-N 3Å; C228-F314 HydrophobicContact CB-CE2 3.84Å; C228-F314 HydrophobicContact CB-CZ 3.97Å; C228-F318 HydrophobicContact CB-CB 4.17Å; C228-F318 HydrophobicContact CB-CD1 3.84Å; C228-F318 HydrophobicContact CB-CD2 4.46Å; C228-F318 HydrophobicContact CB-CE1 4.43Å; C228-F318 HydrophobicContact CB-CG 3.88Å; C228-D320 WeakPolarHBondContact CA-O 3.4Å; C228-I321 HydrophobicContact CB-CG1 4.34Å
229S86.5Confident68.9Low18 Ų1852.3 Ų52.313%0.12633%0.327CS..EExtended strand (participates in β ladder)trans-143.8152.217759.90000111.5H244 D319 D320S229-H244 WeakPolarHBondContact CA-O 3.37Å; S229-D319 PolarHBondContact O-N 2.79Å; S229-D320 PolarHBondContact N-O 2.81Å; S229-D320 VanDerWaalsContact N-O 3.07Å; S229-D320 PolarHBondContact O-N 3.47Å
230T76.5Confident66.9Low17 Ų1756 Ų5610%0.10434%0.342CS..  trans-108.1135.8173.956.90000109.5H243 F318 D319T230-H243 WeakPolarHBondContact O-CA 3.21Å; T230-H243 PolarHBondContact O-N 2.79Å; T230-F318 HydrophobicContact CG2-CD1 3.56Å; T230-F318 HydrophobicContact CG2-CE1 3.85Å; T230-F318 HydrophobicContact CG2-CG 4.48Å; T230-D319 WeakPolarHBondContact CA-OD2 3.46Å
231H61.2Low65.1Low61 Ų6157.3 Ų57.328%0.28235%0.349SS..SBendtrans-93.4-15172.3-67.5-59.3000112.8R185 H243 D319 D320R185-H231 PolarHBondContact NH2-CE1 3.39Å; R185-H231 PolarHBondContact NH2-NE2 2.99Å; R185-H231 VanDerWaalsContact NH2-NE2 3.16Å; H231-H243 AromaticContact ND1-CE1 3.53Å; H231-H243 AromaticContact ND1-ND1 3.24Å; H231-H243 PolarHBondContact ND1-ND1 3.29Å; H231-D319 HydrophobicContact CB-CB 4.44Å; H231-D319 WeakPolarHBondContact CD2-CB 3.49Å; H231-D319 IonicContact CD2-OD1 2.74Å; H231-D319 PolarHBondContact N-OD2 2.87Å; H231-D320 IonicContact CD2-OD2 3.38Å; H231-D320 IonicContact CE1-OD2 2.72Å; H231-D320 IonicContact NE2-OD2 3.67Å; H231-D320 PolarHBondContact NE2-OD2 3.3Å
232S52.2Low63.7Low63 Ų6359.4 Ų59.444%0.44136%0.359SS..SBendtrans-158.1149.1178.6-49.40000110.3P234S232-P234 WeakPolarHBondContact O-CD 3.24Å
233T45.8Very low62.7Low46 Ų4656.7 Ų56.728%0.28235%0.347SS..  trans-80.4125.5176.50.90000111.2G235 L237 D241T233-G235 PolarHBondContact O-N 3.09Å; T233-L237 HydrophobicContact CG2-CB 3.76Å; T233-D241 HydrophobicContact CG2-CB 4.42Å
234P37.7Very low62.4Low69 Ų6953.6 Ų53.645%0.44833%0.332SS..SBendtrans-76.9105.1158.7-12.431.3000108.2S232S232-P234 WeakPolarHBondContact O-CD 3.24Å
235G39.9Very low62.3Low65 Ų6553.2 Ų53.267%0.6733%0.33SS*.SBendtrans73.991166.800000116.7T233 L237T233-G235 PolarHBondContact O-N 3.09Å; G235-L237 PolarHBondContact O-N 2.68Å
236G37.6Very low62.3Low87 Ų8753.4 Ų53.490%0.89733%0.33SS*.SBendtrans81.71.9144.900000119.5
237L38.5Very low62.3Low84 Ų8453.4 Ų53.444%0.4433%0.331SS..  trans-87.5140.8164.6-92.788.1000110.6T233 G235 D241T233-L237 HydrophobicContact CG2-CB 3.76Å; G235-L237 PolarHBondContact O-N 2.68Å; L237-D241 HydrophobicContact CB-CB 4.48Å; L237-D241 WeakPolarHBondContact CB-OD2 3.32Å; L237-D241 WeakPolarHBondContact CD2-OD2 3.36Å
238G39.6Very low62.3Low46 Ų4653.6 Ų53.647%0.47433%0.332SS..  trans-64.4169.8-16500000115.2L240 D241G238-L240 PolarHBondContact O-N 3.14Å; G238-D241 PolarHBondContact O-N 3.12Å; G238-D241 VanDerWaalsContact O-N 3.07Å
239E38.1Very low62.4Low177 Ų17754.3 Ų54.383%0.82734%0.335SS*.G310 helixtrans-53.7-18.7-177-69.8-177.115100114.9D241E239-D241 VanDerWaalsContact C-N 3.31Å; E239-D241 PolarHBondContact O-N 2.6Å
240L42.1Very low62.6Low141 Ų14154.5 Ų54.574%0.73833%0.334SS*.G310 helixtrans-73.7-13.8178.2-116.881.6000114.9G238G238-L240 PolarHBondContact O-N 3.14Å
241D49.8Very low63.4Low29 Ų2954.2 Ų54.216%0.15533%0.331CS..G310 helixtrans-98.66-173.7-62.4-44.5000113.6T233 L237 G238 E239 W271T233-D241 HydrophobicContact CG2-CB 4.42Å; L237-D241 HydrophobicContact CB-CB 4.48Å; L237-D241 WeakPolarHBondContact CB-OD2 3.32Å; L237-D241 WeakPolarHBondContact CD2-OD2 3.36Å; G238-D241 PolarHBondContact O-N 3.12Å; G238-D241 VanDerWaalsContact O-N 3.07Å; E239-D241 VanDerWaalsContact C-N 3.31Å; E239-D241 PolarHBondContact O-N 2.6Å; D241-W271 WeakPolarHBondContact OD1-CH2 3.43Å; D241-W271 WeakPolarHBondContact OD1-CZ3 3.47Å
242Q56.2Low64.9Low92 Ų9253.2 Ų53.243%0.4333%0.328SS..THydrogen-bonded Turntrans-84.8138.3176.4-60.5179.112.700110.7H244Q242-H244 VanDerWaalsContact C-N 3.28Å; Q242-H244 PolarHBondContact O-N 3.44Å
243H65.2Low66.8Low90 Ų9054.3 Ų54.342%0.41733%0.328SS..THydrogen-bonded Turntrans60.931.7178.4-52.8-67.2000114.6T230 H231 K411T230-H243 WeakPolarHBondContact O-CA 3.21Å; T230-H243 PolarHBondContact O-N 2.79Å; H231-H243 AromaticContact ND1-CE1 3.53Å; H231-H243 AromaticContact ND1-ND1 3.24Å; H231-H243 PolarHBondContact ND1-ND1 3.29Å; H243-K411 PolarHBondContact NE2-NZ 2.72Å
244H83Confident69.1Low11 Ų1152.8 Ų52.85%0.05132%0.319CS..  trans-86137.9175.6-16950.9000111.7C74 S229 Q242 N269 W271C74-H244 WeakPolarHBondContact CB-CE1 3.39Å; C74-H244 WeakPolarHBondContact CB-ND1 3.37Å; C74-H244 PolarHBondContact SG-ND1 2.86Å; S229-H244 WeakPolarHBondContact CA-O 3.37Å; Q242-H244 VanDerWaalsContact C-N 3.28Å; Q242-H244 PolarHBondContact O-N 3.44Å; H244-N269 PolarHBondContact NE2-OD1 2.86Å; H244-W271 HydrophobicContact CB-CH2 4.43Å; H244-W271 AromaticContact CD2-CH2 3.93Å; H244-W271 AromaticContact CE1-CD2 3.84Å; H244-W271 AromaticContact CE1-CE2 3.4Å; H244-W271 AromaticContact CE1-CZ2 3.64Å; H244-W271 AromaticContact CE1-NE1 3.58Å; H244-W271 AromaticContact CG-CH2 3.96Å; H244-W271 AromaticContact CG-CZ2 3.91Å; H244-W271 AromaticContact ND1-CE2 3.89Å; H244-W271 AromaticContact ND1-CZ2 3.66Å; H244-W271 AromaticContact NE2-CD2 3.67Å; H244-W271 AromaticContact NE2-CE2 3.68Å; H244-W271 AromaticContact NE2-CE3 3.9Å; H244-W271 AromaticContact NE2-CZ2 3.91Å
245A88.3Confident71.8Confident5 Ų557.7 Ų57.74%0.04133%0.329CS..EExtended strand (participates in β ladder)trans-96.1133.8176.400000110.8C74 V171 P270C74-A245 HydrophobicContact CB-CB 4.42Å; C74-A245 PolarHBondContact SG-N 2.77Å; V171-A245 HydrophobicContact CG2-CB 3.6Å; A245-P270 WeakPolarHBondContact O-CD 3.11Å; A245-P270 WeakPolarHBondContact O-CG 3.47Å
246L92.1Very high74.4Confident9 Ų957.5 Ų57.55%0.04731%0.309CS..EExtended strand (participates in β ladder)trans-123.5155.6174.2-52.794.3000110.3S227 C228 I267 R268 N269 F307 F318S227-L246 CarbonylContact C-O 3.59Å; S227-L246 WeakPolarHBondContact CA-O 3.44Å; S227-L246 VanDerWaalsContact CB-O 3.27Å; S227-L246 WeakPolarHBondContact CB-O 3.33Å; S227-L246 PolarHBondContact OG-O 2.77Å; C228-L246 PolarHBondContact N-O 2.85Å; C228-L246 PolarHBondContact O-N 3Å; L246-I267 HydrophobicContact CB-CG2 3.6Å; L246-I267 HydrophobicContact CD2-CG2 3.75Å; L246-I267 HydrophobicContact CG-CG2 4.31Å; L246-R268 WeakPolarHBondContact CB-O 3.47Å; L246-N269 HydrophobicContact CD2-CB 4.12Å; L246-F307 HydrophobicContact CD2-CE1 4Å; L246-F307 HydrophobicContact CD2-CZ 3.78Å; L246-F318 HydrophobicContact CD1-CE1 3.75Å
247T93.3Very high77Confident8 Ų858.6 Ų58.65%0.04930%0.298CS..EExtended strand (participates in β ladder)trans-101.4132.3178.9-57.40000110.4C78 T81 M249 I267 R268C78-T247 WeakPolarHBondContact CA-OG1 3.48Å; C78-T247 PolarHBondContact SG-OG1 3.41Å; T81-T247 HydrophobicContact CG2-CG2 3.96Å; T247-M249 HydrophobicContact CG2-SD 3.65Å; T247-M249 PolarHBondContact O-N 3.38Å; T247-I267 CarbonylContact O-C 3.59Å; T247-I267 WeakPolarHBondContact O-CA 3.29Å; T247-R268 PolarHBondContact N-O 3.47Å; T247-R268 PolarHBondContact O-N 3.5Å
248V93.9Very high79.5Confident7 Ų759 Ų594%0.04231%0.309CS..EExtended strand (participates in β ladder)trans-82111.8168.2-174.80000107.4L226 W251 L265 I267 F314L226-V248 HydrophobicContact CB-CB 3.69Å; L226-V248 HydrophobicContact CB-CG1 4.47Å; L226-V248 HydrophobicContact CB-CG2 4.01Å; L226-V248 HydrophobicContact CD1-CG1 4.47Å; L226-V248 PolarHBondContact O-N 3.13Å; V248-W251 HydrophobicContact CG1-CE3 4.25Å; V248-L265 HydrophobicContact CG1-CD2 4.3Å; V248-I267 HydrophobicContact CB-CD1 4.1Å; V248-I267 HydrophobicContact CG1-CD1 4.09Å; V248-I267 HydrophobicContact CG2-CD1 3.73Å; V248-F314 HydrophobicContact CG2-CE2 4.37Å; V248-F314 HydrophobicContact CG2-CZ 4.16Å
249M92.2Very high81.9Confident15 Ų1559.1 Ų59.17%0.07431%0.31CS..EExtended strand (participates in β ladder)trans-84.6-40.5-174.2-64.5-57-71.500112.4T81 K85 T247 R266 R268T81-M249 HydrophobicContact CG2-CE 3.95Å; T81-M249 HydrophobicContact CG2-SD 3.69Å; K85-M249 PolarHBondContact NZ-O 2.88Å; T247-M249 HydrophobicContact CG2-SD 3.65Å; T247-M249 PolarHBondContact O-N 3.38Å; M249-R266 HydrophobicContact CB-CB 4.44Å; M249-R266 HydrophobicContact CB-CG 4.41Å; M249-R266 PolarHBondContact N-O 2.81Å; M249-R268 HydrophobicContact CG-CB 3.53Å; M249-R268 HydrophobicContact SD-CB 3.87Å
250E91.7Very high84.6Confident23 Ų2353.4 Ų53.411%0.10729%0.29CS..EExtended strand (participates in β ladder)trans-158.4161.9174.880.6-166.2119.400110.1L265 R266 R301 W308E250-L265 WeakPolarHBondContact O-CA 3.31Å; E250-R266 HydrophobicContact CG-CB 3.81Å; E250-R266 PolarHBondContact O-N 2.8Å; E250-R266 IonicContact OE1-CZ 3.58Å; E250-R266 IonicContact OE1-NE 3.74Å; E250-R266 PolarHBondContact OE1-NE 3.07Å; E250-R266 IonicContact OE1-NH2 3.56Å; E250-R266 PolarHBondContact OE1-NH2 2.87Å; E250-R301 IonicContact OE2-NH1 3.83Å; E250-R301 PolarHBondContact OE2-NH1 3.49Å; E250-R301 VanDerWaalsContact OE2-NH1 3.1Å; E250-W308 VanDerWaalsContact CD-CH2 3.43Å; E250-W308 HydrophobicContact CG-CH2 3.57Å; E250-W308 HydrophobicContact CG-CZ2 4.35Å; E250-W308 HydrophobicContact CG-CZ3 4.08Å; E250-W308 WeakPolarHBondContact OE1-CH2 3.37Å; E250-W308 WeakPolarHBondContact OE1-CZ2 3.43Å
251W92.7Very high87Confident10 Ų1052.7 Ų52.74%0.03828%0.282CS..EExtended strand (participates in β ladder)trans-140.3147.8165.365.5101.6000110.5L217 K221 L226 V248 L264 L265L217-W251 HydrophobicContact CB-CZ2 4.15Å; K221-W251 VanDerWaalsContact CA-CH2 3.46Å; K221-W251 HydrophobicContact CB-CH2 3.76Å; K221-W251 HydrophobicContact CB-CZ2 3.49Å; K221-W251 VanDerWaalsContact CB-CZ2 3.49Å; K221-W251 HydrophobicContact CD-CD2 4.29Å; K221-W251 HydrophobicContact CD-CZ2 3.98Å; K221-W251 WeakPolarHBondContact CE-O 3.3Å; K221-W251 HydrophobicContact CG-CD2 4.13Å; K221-W251 HydrophobicContact CG-CE3 4.28Å; K221-W251 HydrophobicContact CG-CH2 3.58Å; K221-W251 HydrophobicContact CG-CZ2 3.38Å; K221-W251 HydrophobicContact CG-CZ3 3.99Å; K221-W251 PolarHBondContact NZ-O 2.93Å; K221-W251 WeakPolarHBondContact O-CH2 3.41Å; K221-W251 WeakPolarHBondContact O-CZ3 3.39Å; L226-W251 HydrophobicContact CD1-CE3 4Å; L226-W251 HydrophobicContact CD1-CH2 3.45Å; L226-W251 VanDerWaalsContact CD1-CH2 3.45Å; L226-W251 HydrophobicContact CD1-CZ2 4.34Å; L226-W251 HydrophobicContact CD1-CZ3 3.29Å; L226-W251 HydrophobicContact CG-CZ3 4.43Å; V248-W251 HydrophobicContact CG1-CE3 4.25Å; W251-L264 CarbonylContact C-O 3.5Å; W251-L264 WeakPolarHBondContact CA-O 3.46Å; W251-L265 HydrophobicContact CB-CB 4.49Å; W251-L265 HydrophobicContact CB-CD2 4.39Å; W251-L265 HydrophobicContact CB-CG 3.87Å
252L92.8Very high89.1Confident40 Ų4052 Ų5221%0.20928%0.279CS..EExtended strand (participates in β ladder)trans-147.4140.6-173.3-62.2165.3000110.5V254 R263 L264 L298 W308L252-V254 HydrophobicContact CB-CG2 4.18Å; L252-R263 CarbonylContact O-C 3.54Å; L252-R263 WeakPolarHBondContact O-CA 3.21Å; L252-L264 PolarHBondContact N-O 3.41Å; L252-L264 PolarHBondContact O-N 3.34Å; L252-L298 HydrophobicContact CD1-CD2 3.86Å; L252-W308 HydrophobicContact CD1-CH2 4.02Å
253D92.6Very high90.8Very high86 Ų8648.7 Ų48.746%0.4626%0.263SS..EExtended strand (participates in β ladder)trans-87.5121.5167.6-65.1-38.3000108.8R263D253-R263 VanDerWaalsContact OD1-CB 3.29Å; D253-R263 WeakPolarHBondContact OD1-CB 3.11Å; D253-R263 IonicContact OD1-CZ 2.67Å; D253-R263 IonicContact OD1-NE 3.22Å; D253-R263 PolarHBondContact OD1-NE 2.82Å; D253-R263 IonicContact OD1-NH2 2.64Å; D253-R263 PolarHBondContact OD1-NH2 2.87Å; D253-R263 IonicContact OD2-CZ 3.91Å; D253-R263 IonicContact OD2-NE 3.15Å; D253-R263 IonicContact OD2-NH2 2.66Å; D253-R263 PolarHBondContact OD2-NH2 2.9Å
254V94Very high92.2Very high15 Ų1544.4 Ų44.49%0.09124%0.243CC..EExtended strand (participates in β ladder)trans-124.1134.2-174-168.80000109.6L252 E261 V262 L264 L290 L298L252-V254 HydrophobicContact CB-CG2 4.18Å; V254-E261 CarbonylContact O-C 3.49Å; V254-E261 WeakPolarHBondContact O-CA 3.36Å; V254-V262 HydrophobicContact CB-CG1 4.46Å; V254-V262 PolarHBondContact N-O 3.16Å; V254-V262 PolarHBondContact O-N 3.31Å; V254-L264 HydrophobicContact CG2-CD1 4.14Å; V254-L264 HydrophobicContact CG2-CG 4.43Å; V254-L290 HydrophobicContact CB-CD2 4.35Å; V254-L290 HydrophobicContact CG1-CD1 4.01Å; V254-L290 HydrophobicContact CG1-CD2 3.74Å; V254-L290 HydrophobicContact CG1-CG 4.47Å; V254-L298 HydrophobicContact CG2-CD1 4.1Å
255R94.4Very high92.8Very high172 Ų17243.9 Ų43.965%0.64924%0.241SC*.EExtended strand (participates in β ladder)trans-79.1126176.9-174.7170.7-73.4-177.1-2.6110.7
256K93.7Very high93Very high60 Ų6045.7 Ų45.726%0.26125%0.246SC..BIsolated β-bridgetrans-75.2160.1171.4-59.5-171.4-167.6-179.10111.1S258 G259 S260 V262 F289 L290K256-S258 WeakPolarHBondContact CB-OG 3.23Å; K256-S258 PolarHBondContact O-N 3.46Å; K256-G259 PolarHBondContact O-N 3.35Å; K256-S260 VanDerWaalsContact CB-O 3.28Å; K256-S260 WeakPolarHBondContact CB-O 3.21Å; K256-S260 WeakPolarHBondContact CG-O 3.48Å; K256-S260 PolarHBondContact N-O 3.24Å; K256-V262 HydrophobicContact CD-CG1 4.39Å; K256-V262 VanDerWaalsContact CE-CB 3.4Å; K256-V262 HydrophobicContact CG-CB 4.42Å; K256-V262 HydrophobicContact CG-CG1 3.85Å; K256-F289 CarbonylContact C-O 3.6Å; K256-F289 WeakPolarHBondContact CA-O 3.21Å; K256-F289 WeakPolarHBondContact CB-O 3.41Å; K256-F289 HydrophobicContact CD-CB 4.23Å; K256-F289 HydrophobicContact CG-CB 4.47Å; K256-L290 HydrophobicContact CG-CD2 4.34Å
257V93.1Very high93Very high110 Ų11045.2 Ų45.267%0.66724%0.244SC*.THydrogen-bonded Turntrans-57.8-29.9171.9-179.70000111.7G259 F289V257-G259 PolarHBondContact O-N 3.45Å; V257-F289 PolarHBondContact N-O 3.25Å
258S91.5Very high92.9Very high93 Ų9345 Ų4565%0.6524%0.242SC*.THydrogen-bonded Turntrans-69.2-7.7174.157.50000114.6K256 S260K256-S258 WeakPolarHBondContact CB-OG 3.23Å; K256-S258 PolarHBondContact O-N 3.46Å; S258-S260 VanDerWaalsContact C-N 3.33Å; S258-S260 PolarHBondContact O-N 3.36Å; S258-S260 PolarHBondContact OG-OG 3.12Å
259G90.3Very high92.7Very high49 Ų4944.7 Ų44.751%0.50524%0.24SC..SBendtrans88.9-16.2-176.300000115K256 V257K256-G259 PolarHBondContact O-N 3.35Å; V257-G259 PolarHBondContact O-N 3.45Å
260S92.9Very high92.4Very high57 Ų5744.2 Ų44.240%0.39924%0.238SC..  trans-74.6154.1172.759.30000111.9K256 S258K256-S260 VanDerWaalsContact CB-O 3.28Å; K256-S260 WeakPolarHBondContact CB-O 3.21Å; K256-S260 WeakPolarHBondContact CG-O 3.48Å; K256-S260 PolarHBondContact N-O 3.24Å; S258-S260 VanDerWaalsContact C-N 3.33Å; S258-S260 PolarHBondContact O-N 3.36Å; S258-S260 PolarHBondContact OG-OG 3.12Å
261E93.4Very high91.9Very high125 Ų12545.2 Ų45.258%0.58424%0.241SC*.EExtended strand (participates in β ladder)trans-92.5154.6174.4-68.6179159.600112.3V254V254-E261 CarbonylContact O-C 3.49Å; V254-E261 WeakPolarHBondContact O-CA 3.36Å
262V93.3Very high90.9Very high16 Ų1645.1 Ų45.110%0.09724%0.243CC..EExtended strand (participates in β ladder)trans-136.2133.617054.90000109.9V254 K256 L264 W280 L290 D310V254-V262 HydrophobicContact CB-CG1 4.46Å; V254-V262 PolarHBondContact N-O 3.16Å; V254-V262 PolarHBondContact O-N 3.31Å; K256-V262 HydrophobicContact CD-CG1 4.39Å; K256-V262 VanDerWaalsContact CE-CB 3.4Å; K256-V262 HydrophobicContact CG-CB 4.42Å; K256-V262 HydrophobicContact CG-CG1 3.85Å; V262-L264 HydrophobicContact CG1-CD2 4.39Å; V262-L264 HydrophobicContact CG1-CG 4.39Å; V262-L264 HydrophobicContact CG2-CD2 3.85Å; V262-L264 HydrophobicContact CG2-CG 4.47Å; V262-W280 HydrophobicContact CG1-CH2 4.13Å; V262-W280 HydrophobicContact CG1-CZ2 4.22Å; V262-W280 HydrophobicContact CG2-CZ2 4.16Å; V262-L290 HydrophobicContact CG1-CD2 4.24Å; V262-D310 HydrophobicContact CG2-CB 3.8Å
263R93.1Very high90Very high22 Ų2249.5 Ų49.58%0.08326%0.257CS..EExtended strand (participates in β ladder)trans-86.5119.5171.2-176.4163-69.6167-4.3110N215 L252 D253 L265 D310 E311N215-R263 PolarHBondContact OD1-NH1 2.72Å; N215-R263 PolarHBondContact OD1-NH2 3.27Å; L252-R263 CarbonylContact O-C 3.54Å; L252-R263 WeakPolarHBondContact O-CA 3.21Å; D253-R263 VanDerWaalsContact OD1-CB 3.29Å; D253-R263 WeakPolarHBondContact OD1-CB 3.11Å; D253-R263 IonicContact OD1-CZ 2.67Å; D253-R263 IonicContact OD1-NE 3.22Å; D253-R263 PolarHBondContact OD1-NE 2.82Å; D253-R263 IonicContact OD1-NH2 2.64Å; D253-R263 PolarHBondContact OD1-NH2 2.87Å; D253-R263 IonicContact OD2-CZ 3.91Å; D253-R263 IonicContact OD2-NE 3.15Å; D253-R263 IonicContact OD2-NH2 2.66Å; D253-R263 PolarHBondContact OD2-NH2 2.9Å; R263-L265 HydrophobicContact CG-CD1 4.34Å; R263-D310 CarbonylContact O-C 3.46Å; R263-D310 VanDerWaalsContact O-CA 3.27Å; R263-D310 WeakPolarHBondContact O-CA 3.41Å; R263-E311 HydrophobicContact CB-CB 3.98Å; R263-E311 HydrophobicContact CG-CB 4.23Å; R263-E311 IonicContact NH1-OE1 3.1Å; R263-E311 PolarHBondContact NH1-OE1 3.32Å; R263-E311 IonicContact NH1-OE2 2.84Å; R263-E311 PolarHBondContact O-N 2.77Å
264L94.9Very high88.9Confident0 Ų048.7 Ų48.70%026%0.257CS..EExtended strand (participates in β ladder)trans-107.8138.7177-61-177000110.5W251 L252 V254 V262 W280 L290 L298 W308 L309 D310W251-L264 CarbonylContact C-O 3.5Å; W251-L264 WeakPolarHBondContact CA-O 3.46Å; L252-L264 PolarHBondContact N-O 3.41Å; L252-L264 PolarHBondContact O-N 3.34Å; V254-L264 HydrophobicContact CG2-CD1 4.14Å; V254-L264 HydrophobicContact CG2-CG 4.43Å; V262-L264 HydrophobicContact CG1-CD2 4.39Å; V262-L264 HydrophobicContact CG1-CG 4.39Å; V262-L264 HydrophobicContact CG2-CD2 3.85Å; V262-L264 HydrophobicContact CG2-CG 4.47Å; L264-W280 HydrophobicContact CD1-CD2 4.36Å; L264-W280 HydrophobicContact CD1-CE3 3.81Å; L264-W280 HydrophobicContact CD1-CH2 4.13Å; L264-W280 HydrophobicContact CD1-CZ3 3.68Å; L264-W280 HydrophobicContact CD2-CD2 3.5Å; L264-W280 VanDerWaalsContact CD2-CD2 3.5Å; L264-W280 HydrophobicContact CD2-CE3 3.82Å; L264-W280 HydrophobicContact CD2-CG 4.03Å; L264-W280 HydrophobicContact CD2-CH2 3.93Å; L264-W280 HydrophobicContact CD2-CZ2 3.63Å; L264-W280 HydrophobicContact CD2-CZ3 4.03Å; L264-W280 HydrophobicContact CG-CZ3 4.5Å; L264-L290 HydrophobicContact CD1-CD1 4.15Å; L264-L298 HydrophobicContact CD1-CD1 4.09Å; L264-W308 HydrophobicContact CB-CE3 3.75Å; L264-W308 HydrophobicContact CB-CZ3 3.92Å; L264-L309 CarbonylContact C-O 3.41Å; L264-L309 WeakPolarHBondContact CA-O 3.38Å; L264-D310 HydrophobicContact CD2-CB 4.05Å
265L93.8Very high87.7Confident0 Ų050 Ų500%027%0.267CS..EExtended strand (participates in β ladder)trans-118.6129.9176.9-62.490.4000109.4L214 V248 E250 W251 R263 I267 W308 L309 E311 F314L214-L265 HydrophobicContact CD1-CD2 3.98Å; V248-L265 HydrophobicContact CG1-CD2 4.3Å; E250-L265 WeakPolarHBondContact O-CA 3.31Å; W251-L265 HydrophobicContact CB-CB 4.49Å; W251-L265 HydrophobicContact CB-CD2 4.39Å; W251-L265 HydrophobicContact CB-CG 3.87Å; R263-L265 HydrophobicContact CG-CD1 4.34Å; L265-I267 HydrophobicContact CB-CD1 4.17Å; L265-W308 VanDerWaalsContact C-CE3 3.48Å; L265-W308 WeakPolarHBondContact O-CA 3.36Å; L265-L309 HydrophobicContact CB-CD1 4.14Å; L265-L309 HydrophobicContact CD1-CD1 4.23Å; L265-L309 PolarHBondContact N-O 3.45Å; L265-L309 PolarHBondContact O-N 3.45Å; L265-L309 VanDerWaalsContact O-N 3.08Å; L265-E311 HydrophobicContact CD1-CB 4.08Å; L265-F314 HydrophobicContact CD1-CB 4.26Å; L265-F314 HydrophobicContact CD1-CG 4.43Å; L265-F314 HydrophobicContact CD2-CD1 3.79Å; L265-F314 HydrophobicContact CD2-CD2 4.08Å; L265-F314 HydrophobicContact CD2-CE1 3.78Å; L265-F314 HydrophobicContact CD2-CE2 4.14Å; L265-F314 HydrophobicContact CD2-CG 3.92Å; L265-F314 HydrophobicContact CD2-CZ 3.99Å
266R93.6Very high86.9Confident42 Ų4244.2 Ų44.216%0.15825%0.245CC..EExtended strand (participates in β ladder)trans-93.4119.2169.4-171.517051.7138.2-13.8109.2M249 E250 R301 E306 F307 W308M249-R266 HydrophobicContact CB-CB 4.44Å; M249-R266 HydrophobicContact CB-CG 4.41Å; M249-R266 PolarHBondContact N-O 2.81Å; E250-R266 HydrophobicContact CG-CB 3.81Å; E250-R266 PolarHBondContact O-N 2.8Å; E250-R266 IonicContact OE1-CZ 3.58Å; E250-R266 IonicContact OE1-NE 3.74Å; E250-R266 PolarHBondContact OE1-NE 3.07Å; E250-R266 IonicContact OE1-NH2 3.56Å; E250-R266 PolarHBondContact OE1-NH2 2.87Å; R266-R301 PolarHBondContact NH1-O 3.01Å; R266-R301 VanDerWaalsContact NH1-O 3.09Å; R266-E306 WeakPolarHBondContact CD-OE2 3.31Å; R266-E306 HydrophobicContact CG-CB 4.42Å; R266-E306 IonicContact CZ-OE2 2.66Å; R266-E306 IonicContact NE-OE2 3.67Å; R266-E306 IonicContact NH1-OE1 2.7Å; R266-E306 IonicContact NH1-OE2 3.1Å; R266-E306 PolarHBondContact NH1-OE2 2.98Å; R266-F307 CarbonylContact C-O 3.54Å; R266-F307 WeakPolarHBondContact CA-O 3.34Å; R266-W308 HydrophobicContact CB-CD2 3.88Å; R266-W308 HydrophobicContact CB-CE3 3.88Å; R266-W308 HydrophobicContact CB-CH2 3.9Å; R266-W308 HydrophobicContact CB-CZ2 3.87Å; R266-W308 HydrophobicContact CB-CZ3 3.9Å; R266-W308 HydrophobicContact CG-CD2 4.33Å; R266-W308 HydrophobicContact CG-CZ2 4.29Å
267I92.4Very high86Confident0 Ų045.9 Ų45.90%027%0.269CS..EExtended strand (participates in β ladder)trans-109.3143.6-179.1-53-56.2000109.5L246 T247 V248 L265 E306 F307 L309 F314L246-I267 HydrophobicContact CB-CG2 3.6Å; L246-I267 HydrophobicContact CD2-CG2 3.75Å; L246-I267 HydrophobicContact CG-CG2 4.31Å; T247-I267 CarbonylContact O-C 3.59Å; T247-I267 WeakPolarHBondContact O-CA 3.29Å; V248-I267 HydrophobicContact CB-CD1 4.1Å; V248-I267 HydrophobicContact CG1-CD1 4.09Å; V248-I267 HydrophobicContact CG2-CD1 3.73Å; L265-I267 HydrophobicContact CB-CD1 4.17Å; I267-E306 CarbonylContact O-C 3.13Å; I267-E306 WeakPolarHBondContact O-CA 3.44Å; I267-F307 HydrophobicContact CB-CD2 4.29Å; I267-F307 HydrophobicContact CB-CE1 4.26Å; I267-F307 HydrophobicContact CB-CE2 3.89Å; I267-F307 HydrophobicContact CB-CZ 3.87Å; I267-F307 HydrophobicContact CG1-CE2 4.32Å; I267-F307 HydrophobicContact CG2-CE1 4.16Å; I267-F307 HydrophobicContact CG2-CE2 4.21Å; I267-F307 HydrophobicContact CG2-CZ 3.74Å; I267-F307 PolarHBondContact N-O 3.07Å; I267-F307 PolarHBondContact O-N 3.24Å; I267-L309 HydrophobicContact CG1-CD2 3.71Å; I267-L309 HydrophobicContact CG1-CG 4.2Å; I267-F314 HydrophobicContact CD1-CD2 4.42Å; I267-F314 HydrophobicContact CD1-CE2 3.99Å
268R90.9Very high85.4Confident3 Ų341.6 Ų41.61%0.01125%0.247CC..EExtended strand (participates in β ladder)trans-116.9125.5176.4-178.1175.7-172.891.317.4110.8H142 L246 T247 M249 E306H142-R268 PolarHBondContact CE1-NH2 3.14Å; H142-R268 PolarHBondContact NE2-NH2 3.15Å; L246-R268 WeakPolarHBondContact CB-O 3.47Å; T247-R268 PolarHBondContact N-O 3.47Å; T247-R268 PolarHBondContact O-N 3.5Å; M249-R268 HydrophobicContact CG-CB 3.53Å; M249-R268 HydrophobicContact SD-CB 3.87Å; R268-E306 HydrophobicContact CB-CG 3.93Å; R268-E306 HydrophobicContact CG-CG 3.93Å; R268-E306 IonicContact CZ-OE1 3.32Å; R268-E306 IonicContact NH1-OE1 2.67Å; R268-E306 PolarHBondContact NH1-OE1 2.96Å
269N89.5Confident85.2Confident0 Ų038.8 Ų38.80%023%0.23CC..  trans-90.2119.5171.1-173.6-21000110.5H244 L246 W271 G272 C275 G305 F307H244-N269 PolarHBondContact NE2-OD1 2.86Å; L246-N269 HydrophobicContact CD2-CB 4.12Å; N269-W271 VanDerWaalsContact ND2-CE3 3.26Å; N269-W271 PolarHBondContact O-N 3.44Å; N269-W271 VanDerWaalsContact O-N 3.1Å; N269-W271 WeakPolarHBondContact OD1-CB 3.34Å; N269-W271 PolarHBondContact OD1-N 3.17Å; N269-G272 PolarHBondContact O-N 3.04Å; N269-C275 PolarHBondContact ND2-SG 3.14Å; N269-G305 PolarHBondContact N-O 2.95Å; N269-F307 HydrophobicContact CB-CE1 4.46Å
270P85.4Confident85.1Confident5 Ų536.7 Ų36.73%0.03221%0.207CC..THydrogen-bonded Turntrans-56.8-20.6176.8-26.635.4000115.6K67 Q68 C74 L77 A245 G272K67-P270 CarbonylContact C-O 3.4Å; K67-P270 WeakPolarHBondContact CA-O 3.33Å; Q68-P270 HydrophobicContact CB-CB 4.48Å; Q68-P270 PolarHBondContact N-O 3.32Å; C74-P270 HydrophobicContact CB-CB 4.48Å; C74-P270 HydrophobicContact CB-CG 4.34Å; L77-P270 HydrophobicContact CB-CB 4.22Å; L77-P270 HydrophobicContact CD1-CB 4.35Å; A245-P270 WeakPolarHBondContact O-CD 3.11Å; A245-P270 WeakPolarHBondContact O-CG 3.47Å; P270-G272 PolarHBondContact O-N 3.16Å
271W82.3Confident84.7Confident45 Ų4535 Ų3517%0.1720%0.195CC..THydrogen-bonded Turntrans-67.1-13.8173.7-66-34.3000113.9Q68 D241 H244 N269 R273Q68-W271 VanDerWaalsContact OE1-CD1 3.23Å; Q68-W271 VanDerWaalsContact OE1-NE1 3.14Å; D241-W271 WeakPolarHBondContact OD1-CH2 3.43Å; D241-W271 WeakPolarHBondContact OD1-CZ3 3.47Å; H244-W271 HydrophobicContact CB-CH2 4.43Å; H244-W271 AromaticContact CD2-CH2 3.93Å; H244-W271 AromaticContact CE1-CD2 3.84Å; H244-W271 AromaticContact CE1-CE2 3.4Å; H244-W271 AromaticContact CE1-CZ2 3.64Å; H244-W271 AromaticContact CE1-NE1 3.58Å; H244-W271 AromaticContact CG-CH2 3.96Å; H244-W271 AromaticContact CG-CZ2 3.91Å; H244-W271 AromaticContact ND1-CE2 3.89Å; H244-W271 AromaticContact ND1-CZ2 3.66Å; H244-W271 AromaticContact NE2-CD2 3.67Å; H244-W271 AromaticContact NE2-CE2 3.68Å; H244-W271 AromaticContact NE2-CE3 3.9Å; H244-W271 AromaticContact NE2-CZ2 3.91Å; N269-W271 VanDerWaalsContact ND2-CE3 3.26Å; N269-W271 PolarHBondContact O-N 3.44Å; N269-W271 VanDerWaalsContact O-N 3.1Å; N269-W271 WeakPolarHBondContact OD1-CB 3.34Å; N269-W271 PolarHBondContact OD1-N 3.17Å; W271-R273 HydrophobicContact CB-CG 3.96Å; W271-R273 PolarHBondContact O-N 3.4Å
272G71.6Confident84.1Confident7 Ų737.8 Ų37.87%0.07220%0.2CC..SBendtrans71.419.7-176.100000113.3N269 P270 E304N269-G272 PolarHBondContact O-N 3.04Å; P270-G272 PolarHBondContact O-N 3.16Å; G272-E304 WeakPolarHBondContact O-CG 3.21Å
273R73.9Confident83.5Confident132 Ų13242.3 Ų42.350%0.49823%0.232SC..SBendtrans-126.4138.917364.5-173.4179.7-145.7-1.4110.4W271 C275W271-R273 HydrophobicContact CB-CG 3.96Å; W271-R273 PolarHBondContact O-N 3.4Å; R273-C275 PolarHBondContact O-N 3.21Å
274C68.4Low83.2Confident70 Ų7041.9 Ų41.947%0.47323%0.234SC..  trans-77.6115.9169.8-1780000107.9
275C70Confident83Confident43 Ų4347.8 Ų47.829%0.29127%0.265SS..  trans-109.314.7176.459.60000111.8N269 R273N269-C275 PolarHBondContact ND2-SG 3.14Å; R273-C275 PolarHBondContact O-N 3.21Å
276W76.6Confident82.8Confident50 Ų5047.8 Ų47.819%0.18927%0.265CS..  trans-104131.4-174.2-155.5-95.6000111.4T281 F307 E313 Q317 F318W276-T281 WeakPolarHBondContact O-CG2 3.14Å; W276-F307 HydrophobicContact CB-CB 4.26Å; W276-F307 HydrophobicContact CB-CD1 4.03Å; W276-F307 HydrophobicContact CB-CD2 3.42Å; W276-F307 VanDerWaalsContact CB-CD2 3.42Å; W276-F307 HydrophobicContact CB-CE1 4.19Å; W276-F307 HydrophobicContact CB-CE2 3.57Å; W276-F307 HydrophobicContact CB-CG 3.65Å; W276-F307 HydrophobicContact CB-CZ 3.97Å; W276-F307 AromaticContact CD1-CD2 3.87Å; W276-F307 HydrophobicContact CD2-CD2 4.11Å; W276-F307 AromaticContact CD2-CE2 3.56Å; W276-F307 HydrophobicContact CD2-CE2 3.56Å; W276-F307 HydrophobicContact CD2-CZ 4.16Å; W276-F307 AromaticContact CE3-CE2 3.82Å; W276-F307 HydrophobicContact CE3-CE2 3.82Å; W276-F307 AromaticContact CE3-CZ 3.99Å; W276-F307 HydrophobicContact CE3-CZ 3.99Å; W276-F307 AromaticContact CG-CD2 3.47Å; W276-F307 HydrophobicContact CG-CD2 3.47Å; W276-F307 VanDerWaalsContact CG-CD2 3.47Å; W276-F307 AromaticContact CG-CE2 3.42Å; W276-F307 HydrophobicContact CG-CE2 3.42Å; W276-F307 VanDerWaalsContact CG-CE2 3.42Å; W276-F307 HydrophobicContact CG-CG 4.21Å; W276-F307 HydrophobicContact CG-CZ 4.16Å; W276-E313 HydrophobicContact CZ2-CG 4.28Å; W276-E313 PolarHBondContact NE1-OE1 2.99Å; W276-Q317 HydrophobicContact CH2-CB 3.63Å; W276-Q317 HydrophobicContact CH2-CG 3.63Å; W276-Q317 HydrophobicContact CZ2-CB 4.07Å; W276-Q317 HydrophobicContact CZ2-CG 3.64Å; W276-F318 HydrophobicContact CZ3-CZ 4.28Å
277A75.9Confident82.8Confident94 Ų9446 Ų4678%0.77726%0.258SS*.  trans-114.7112.417100000107.7
278G80.1Confident82.9Confident20 Ų2050.3 Ų50.321%0.20629%0.288CS..SBendtrans-164.8171.2-172.300000112.8W280 T281G278-W280 PolarHBondContact O-N 2.84Å; G278-W280 VanDerWaalsContact O-N 3.15Å; G278-T281 VanDerWaalsContact N-CG2 3.28Å; G278-T281 WeakPolarHBondContact O-CB 3.48Å; G278-T281 WeakPolarHBondContact O-CG2 3.48Å; G278-T281 PolarHBondContact O-N 3.33Å; G278-T281 PolarHBondContact O-OG1 3.34Å
279A86.1Confident83Confident35 Ų3554.9 Ų54.929%0.28931%0.308SS..THydrogen-bonded Turntrans-61.3-25.9-174.800000113.1G284 I285 G286A279-G284 CarbonylContact O-C 3.51Å; A279-G284 WeakPolarHBondContact O-CA 3.28Å; A279-I285 HydrophobicContact CB-CG1 4.46Å; A279-I285 PolarHBondContact O-N 2.81Å; A279-G286 VanDerWaalsContact O-CA 3.24Å; A279-G286 WeakPolarHBondContact O-CA 3.43Å; A279-G286 PolarHBondContact O-N 2.92Å
280W88.3Confident83.2Confident4 Ų455 Ų552%0.01531%0.309CS..THydrogen-bonded Turntrans-106.215.6-176.1-56.797.2000113.3V262 L264 G278 G286 W287 L290 W308 D310V262-W280 HydrophobicContact CG1-CH2 4.13Å; V262-W280 HydrophobicContact CG1-CZ2 4.22Å; V262-W280 HydrophobicContact CG2-CZ2 4.16Å; L264-W280 HydrophobicContact CD1-CD2 4.36Å; L264-W280 HydrophobicContact CD1-CE3 3.81Å; L264-W280 HydrophobicContact CD1-CH2 4.13Å; L264-W280 HydrophobicContact CD1-CZ3 3.68Å; L264-W280 HydrophobicContact CD2-CD2 3.5Å; L264-W280 VanDerWaalsContact CD2-CD2 3.5Å; L264-W280 HydrophobicContact CD2-CE3 3.82Å; L264-W280 HydrophobicContact CD2-CG 4.03Å; L264-W280 HydrophobicContact CD2-CH2 3.93Å; L264-W280 HydrophobicContact CD2-CZ2 3.63Å; L264-W280 HydrophobicContact CD2-CZ3 4.03Å; L264-W280 HydrophobicContact CG-CZ3 4.5Å; G278-W280 PolarHBondContact O-N 2.84Å; G278-W280 VanDerWaalsContact O-N 3.15Å; W280-G286 WeakPolarHBondContact CH2-O 3.43Å; W280-G286 VanDerWaalsContact CZ3-C 3.45Å; W280-G286 VanDerWaalsContact CZ3-O 3.31Å; W280-G286 WeakPolarHBondContact CZ3-O 3.28Å; W280-W287 HydrophobicContact CE3-CD2 4.03Å; W280-W287 AromaticContact CE3-CE3 3.9Å; W280-W287 HydrophobicContact CE3-CE3 3.9Å; W280-W287 HydrophobicContact CE3-CH2 4.43Å; W280-W287 HydrophobicContact CE3-CZ3 4.09Å; W280-W287 HydrophobicContact CZ3-CD2 4.44Å; W280-W287 HydrophobicContact CZ3-CE3 4.03Å; W280-W287 HydrophobicContact CZ3-CZ3 4.38Å; W280-W287 WeakPolarHBondContact O-CZ2 3.43Å; W280-W287 PolarHBondContact O-NE1 3.29Å; W280-L290 HydrophobicContact CH2-CD1 4.16Å; W280-L290 HydrophobicContact CH2-CD2 4.11Å; W280-L290 HydrophobicContact CH2-CG 3.94Å; W280-L290 HydrophobicContact CZ3-CD1 3.63Å; W280-L290 HydrophobicContact CZ3-CD2 4.42Å; W280-L290 HydrophobicContact CZ3-CG 3.81Å; W280-W308 HydrophobicContact CB-CB 3.76Å; W280-W308 WeakPolarHBondContact CB-O 3.13Å; W280-D310 PolarHBondContact NE1-OD2 2.7Å
281T84.7Confident83.6Confident23 Ų2358.8 Ų58.814%0.14133%0.329CS..SBendtrans-70167.2168.457.40000111.9W276 G278 S283 G284 W287W276-T281 WeakPolarHBondContact O-CG2 3.14Å; G278-T281 VanDerWaalsContact N-CG2 3.28Å; G278-T281 WeakPolarHBondContact O-CB 3.48Å; G278-T281 WeakPolarHBondContact O-CG2 3.48Å; G278-T281 PolarHBondContact O-N 3.33Å; G278-T281 PolarHBondContact O-OG1 3.34Å; T281-S283 PolarHBondContact O-N 2.98Å; T281-G284 PolarHBondContact O-N 3.01Å; T281-W287 VanDerWaalsContact O-CD1 3.27Å; T281-W287 PolarHBondContact O-NE1 3.13Å
282W80.6Confident84.2Confident183 Ų18361.5 Ų61.569%0.69335%0.352SS*.THydrogen-bonded Turntrans-47.4-44.4-174.5-174.9-98000114.1R299W282-R299 HydrophobicContact CE3-CB 4.42Å; W282-R299 HydrophobicContact CZ3-CB 4.04Å; W282-R299 PolarHBondContact O-NE 3.32Å
283S81.8Confident85.2Confident111 Ų11166.3 Ų66.378%0.77638%0.38SS*.THydrogen-bonded Turntrans-100.112.9177.958.40000114.3T281T281-S283 PolarHBondContact O-N 2.98Å
284G86.3Confident86.2Confident12 Ų1261.7 Ų61.712%0.12437%0.367CS..  trans-73.6152.1-17500000113.8A279 T281 G286A279-G284 CarbonylContact O-C 3.51Å; A279-G284 WeakPolarHBondContact O-CA 3.28Å; T281-G284 PolarHBondContact O-N 3.01Å; G284-G286 VanDerWaalsContact C-N 3.28Å; G284-G286 PolarHBondContact O-N 3.3Å
285I90.8Very high87.4Confident125 Ų12558.4 Ų58.464%0.64135%0.345SS*.G310 helixtrans-71.4-21-178.459.2166.8000113.6A279 W287 S288A279-I285 HydrophobicContact CB-CG1 4.46Å; A279-I285 PolarHBondContact O-N 2.81Å; I285-W287 PolarHBondContact O-N 3.13Å; I285-S288 WeakPolarHBondContact O-CB 3.48Å; I285-S288 PolarHBondContact O-N 3.19Å; I285-S288 PolarHBondContact O-OG 3.35Å
286G90.6Very high88.5Confident0 Ų059 Ų590%035%0.353CS..G310 helixtrans-56.1-37.4-177.600000112.5A279 W280 G284 S288 F289A279-G286 VanDerWaalsContact O-CA 3.24Å; A279-G286 WeakPolarHBondContact O-CA 3.43Å; A279-G286 PolarHBondContact O-N 2.92Å; W280-G286 WeakPolarHBondContact CH2-O 3.43Å; W280-G286 VanDerWaalsContact CZ3-C 3.45Å; W280-G286 VanDerWaalsContact CZ3-O 3.31Å; W280-G286 WeakPolarHBondContact CZ3-O 3.28Å; G284-G286 VanDerWaalsContact C-N 3.28Å; G284-G286 PolarHBondContact O-N 3.3Å; G286-S288 VanDerWaalsContact C-N 3.25Å; G286-S288 PolarHBondContact O-N 3.36Å; G286-F289 WeakPolarHBondContact O-CB 3.29Å; G286-F289 VanDerWaalsContact O-CD2 3.25Å; G286-F289 WeakPolarHBondContact O-CD2 3.44Å; G286-F289 PolarHBondContact O-N 3.45Å
287W93.8Very high89.3Confident5 Ų561.6 Ų61.62%0.01937%0.367CS..G310 helixtrans-63.5-25.4178.6-60.6112.8000114.9W280 T281 I285 F289 L290 A295 L298 R299 W308W280-W287 HydrophobicContact CE3-CD2 4.03Å; W280-W287 AromaticContact CE3-CE3 3.9Å; W280-W287 HydrophobicContact CE3-CE3 3.9Å; W280-W287 HydrophobicContact CE3-CH2 4.43Å; W280-W287 HydrophobicContact CE3-CZ3 4.09Å; W280-W287 HydrophobicContact CZ3-CD2 4.44Å; W280-W287 HydrophobicContact CZ3-CE3 4.03Å; W280-W287 HydrophobicContact CZ3-CZ3 4.38Å; W280-W287 WeakPolarHBondContact O-CZ2 3.43Å; W280-W287 PolarHBondContact O-NE1 3.29Å; T281-W287 VanDerWaalsContact O-CD1 3.27Å; T281-W287 PolarHBondContact O-NE1 3.13Å; I285-W287 PolarHBondContact O-N 3.13Å; W287-F289 PolarHBondContact O-N 2.9Å; W287-L290 HydrophobicContact CE3-CD1 4.19Å; W287-L290 HydrophobicContact CZ3-CD1 4.38Å; W287-L290 PolarHBondContact O-N 3Å; W287-A295 HydrophobicContact CB-CB 4.44Å; W287-A295 HydrophobicContact CE3-CB 4.27Å; W287-L298 HydrophobicContact CH2-CB 3.97Å; W287-L298 HydrophobicContact CZ3-CB 3.6Å; W287-L298 HydrophobicContact CZ3-CD1 4.17Å; W287-R299 VanDerWaalsContact CD1-NE 3.3Å; W287-R299 HydrophobicContact CD2-CG 3.86Å; W287-R299 HydrophobicContact CE3-CG 4.16Å; W287-R299 HydrophobicContact CG-CG 4.45Å; W287-R299 VanDerWaalsContact CG-NE 3.32Å; W287-R299 HydrophobicContact CH2-CG 4.13Å; W287-R299 HydrophobicContact CZ2-CG 3.8Å; W287-R299 HydrophobicContact CZ3-CG 4.3Å; W287-W308 HydrophobicContact CH2-CB 4.11Å; W287-W308 AromaticContact CH2-CD1 3.63Å; W287-W308 HydrophobicContact CH2-CD2 4.31Å; W287-W308 AromaticContact CH2-CG 3.77Å; W287-W308 HydrophobicContact CH2-CG 3.77Å; W287-W308 HydrophobicContact CZ2-CB 4.09Å; W287-W308 AromaticContact CZ2-CD1 3.8Å; W287-W308 HydrophobicContact CZ2-CG 4.07Å
288S92.6Very high90.2Very high89 Ų8957.3 Ų57.362%0.62233%0.332SS*.G310 helixtrans-71.1-13.1175.468.30000113.2I285 G286 L290I285-S288 WeakPolarHBondContact O-CB 3.48Å; I285-S288 PolarHBondContact O-N 3.19Å; I285-S288 PolarHBondContact O-OG 3.35Å; G286-S288 VanDerWaalsContact C-N 3.25Å; G286-S288 PolarHBondContact O-N 3.36Å; S288-L290 VanDerWaalsContact C-N 3.29Å
289F93.1Very high90.7Very high99 Ų9959.6 Ų59.643%0.43433%0.334SS..G310 helixtrans-82.6-6.9174.6-53.7-49.5000113K256 V257 G286 W287K256-F289 CarbonylContact C-O 3.6Å; K256-F289 WeakPolarHBondContact CA-O 3.21Å; K256-F289 WeakPolarHBondContact CB-O 3.41Å; K256-F289 HydrophobicContact CD-CB 4.23Å; K256-F289 HydrophobicContact CG-CB 4.47Å; V257-F289 PolarHBondContact N-O 3.25Å; G286-F289 WeakPolarHBondContact O-CB 3.29Å; G286-F289 VanDerWaalsContact O-CD2 3.25Å; G286-F289 WeakPolarHBondContact O-CD2 3.44Å; G286-F289 PolarHBondContact O-N 3.45Å; W287-F289 PolarHBondContact O-N 2.9Å
290L94.6Very high90.9Very high4 Ų461.8 Ų61.82%0.02135%0.352CS..BIsolated β-bridgetrans-105160.8178.4-59.4-172.6000111.3V254 K256 V262 L264 W280 W287 S288 A295 L298V254-L290 HydrophobicContact CB-CD2 4.35Å; V254-L290 HydrophobicContact CG1-CD1 4.01Å; V254-L290 HydrophobicContact CG1-CD2 3.74Å; V254-L290 HydrophobicContact CG1-CG 4.47Å; K256-L290 HydrophobicContact CG-CD2 4.34Å; V262-L290 HydrophobicContact CG1-CD2 4.24Å; L264-L290 HydrophobicContact CD1-CD1 4.15Å; W280-L290 HydrophobicContact CH2-CD1 4.16Å; W280-L290 HydrophobicContact CH2-CD2 4.11Å; W280-L290 HydrophobicContact CH2-CG 3.94Å; W280-L290 HydrophobicContact CZ3-CD1 3.63Å; W280-L290 HydrophobicContact CZ3-CD2 4.42Å; W280-L290 HydrophobicContact CZ3-CG 3.81Å; W287-L290 HydrophobicContact CE3-CD1 4.19Å; W287-L290 HydrophobicContact CZ3-CD1 4.38Å; W287-L290 PolarHBondContact O-N 3Å; S288-L290 VanDerWaalsContact C-N 3.29Å; L290-A295 HydrophobicContact CB-CB 4.17Å; L290-L298 HydrophobicContact CD1-CD1 3.99Å
291D94.3Very high91Very high84 Ų8466 Ų6645%0.44937%0.368SS..  trans-55.5136166.7174.8-92000110.3V293 C294 A295D291-V293 VanDerWaalsContact C-N 3.26Å; D291-V293 PolarHBondContact O-N 3.26Å; D291-V293 WeakPolarHBondContact OD1-CA 3.46Å; D291-V293 VanDerWaalsContact OD1-CB 3.26Å; D291-V293 WeakPolarHBondContact OD1-CB 3.23Å; D291-V293 PolarHBondContact OD1-N 2.74Å; D291-C294 HydrophobicContact CB-CB 4.21Å; D291-C294 PolarHBondContact O-N 2.65Å; D291-C294 VanDerWaalsContact O-N 3.17Å; D291-C294 PolarHBondContact OD1-N 2.79Å; D291-A295 WeakPolarHBondContact O-CB 3.31Å; D291-A295 PolarHBondContact O-N 2.93Å
292P93.5Very high91.2Very high101 Ų10166.9 Ų66.966%0.65637%0.374SS*.Hα-helixtrans-57.1-33.6-175.7-27.735.5000114.9A296P292-A296 WeakPolarHBondContact O-CB 3.38Å; P292-A296 PolarHBondContact O-N 3.34Å
293V94.5Very high91.4Very high108 Ų10860.4 Ų60.466%0.65536%0.359SS*.Hα-helixtrans-70.6-47.8178.9-177.50000109.6D291 A295 A296 E297D291-V293 VanDerWaalsContact C-N 3.26Å; D291-V293 PolarHBondContact O-N 3.26Å; D291-V293 WeakPolarHBondContact OD1-CA 3.46Å; D291-V293 VanDerWaalsContact OD1-CB 3.26Å; D291-V293 WeakPolarHBondContact OD1-CB 3.23Å; D291-V293 PolarHBondContact OD1-N 2.74Å; V293-A295 VanDerWaalsContact C-N 3.35Å; V293-A295 PolarHBondContact O-N 2.8Å; V293-A296 PolarHBondContact O-N 2.88Å; V293-E297 PolarHBondContact O-N 2.48Å
294C93.6Very high91.4Very high36 Ų3660.4 Ų60.424%0.24335%0.347CS..Hα-helixtrans-60.3-43.9176-177.30000111.7D291 A296 E297 L298D291-C294 HydrophobicContact CB-CB 4.21Å; D291-C294 PolarHBondContact O-N 2.65Å; D291-C294 VanDerWaalsContact O-N 3.17Å; D291-C294 PolarHBondContact OD1-N 2.79Å; C294-A296 PolarHBondContact O-N 3.06Å; C294-E297 PolarHBondContact O-N 2.81Å; C294-L298 WeakPolarHBondContact O-CG 3.15Å; C294-L298 PolarHBondContact O-N 2.8Å
295A93.4Very high91.2Very high1 Ų160 Ų601%0.00834%0.343CS..Hα-helixtrans-63-39.917800000112.4W287 L290 D291 V293 R299W287-A295 HydrophobicContact CB-CB 4.44Å; W287-A295 HydrophobicContact CE3-CB 4.27Å; L290-A295 HydrophobicContact CB-CB 4.17Å; D291-A295 WeakPolarHBondContact O-CB 3.31Å; D291-A295 PolarHBondContact O-N 2.93Å; V293-A295 VanDerWaalsContact C-N 3.35Å; V293-A295 PolarHBondContact O-N 2.8Å; A295-R299 WeakPolarHBondContact O-CB 3.29Å; A295-R299 VanDerWaalsContact O-CG 3.26Å; A295-R299 WeakPolarHBondContact O-CG 3.17Å; A295-R299 PolarHBondContact O-N 2.92Å; A295-R299 VanDerWaalsContact O-N 3.15Å
296A93.3Very high91.2Very high56 Ų5654.4 Ų54.446%0.46331%0.314SS..Hα-helixtrans-66.5-41.5176.300000111.6P292 V293 C294 A300P292-A296 WeakPolarHBondContact O-CB 3.38Å; P292-A296 PolarHBondContact O-N 3.34Å; V293-A296 PolarHBondContact O-N 2.88Å; C294-A296 PolarHBondContact O-N 3.06Å; A296-A300 WeakPolarHBondContact O-CB 3.35Å; A296-A300 PolarHBondContact O-N 2.96Å
297E94.3Very high91.2Very high103 Ų10354.6 Ų54.648%0.48132%0.315SS..Hα-helixtrans-62.2-50.6178-170.8-170.815900112V293 C294 R299 A300 R301V293-E297 PolarHBondContact O-N 2.48Å; C294-E297 PolarHBondContact O-N 2.81Å; E297-R299 VanDerWaalsContact C-N 3.34Å; E297-R299 PolarHBondContact O-N 3.37Å; E297-A300 PolarHBondContact O-N 3.19Å; E297-R301 WeakPolarHBondContact O-CG 3.36Å; E297-R301 PolarHBondContact O-N 3.09Å; E297-R301 IonicContact OE1-CZ 2.88Å; E297-R301 IonicContact OE1-NE 2.7Å; E297-R301 IonicContact OE1-NH2 3.65Å; E297-R301 PolarHBondContact OE1-NH2 3.11Å
298L93.3Very high91.2Very high5 Ų554.4 Ų54.43%0.02631%0.314CS..Hα-helixtrans-64.8-37.8-179.4-68.1177.6000112.2L252 V254 L264 W287 L290 C294 R301 W308L252-L298 HydrophobicContact CD1-CD2 3.86Å; V254-L298 HydrophobicContact CG2-CD1 4.1Å; L264-L298 HydrophobicContact CD1-CD1 4.09Å; W287-L298 HydrophobicContact CH2-CB 3.97Å; W287-L298 HydrophobicContact CZ3-CB 3.6Å; W287-L298 HydrophobicContact CZ3-CD1 4.17Å; L290-L298 HydrophobicContact CD1-CD1 3.99Å; C294-L298 WeakPolarHBondContact O-CG 3.15Å; C294-L298 PolarHBondContact O-N 2.8Å; L298-R301 PolarHBondContact O-N 3.21Å; L298-W308 HydrophobicContact CB-CZ2 4.45Å; L298-W308 HydrophobicContact CD2-CH2 4.03Å; L298-W308 HydrophobicContact CD2-CZ2 4.11Å; L298-W308 PolarHBondContact O-NE1 3Å
299R91.1Very high91.2Very high67 Ų6750.2 Ų50.225%0.25328%0.284SS..Hα-helixtrans-62.1-43.8173.1-77.9-174.1-173.6115.2-20111.8W282 W287 A295 E297 R301 T302W282-R299 HydrophobicContact CE3-CB 4.42Å; W282-R299 HydrophobicContact CZ3-CB 4.04Å; W282-R299 PolarHBondContact O-NE 3.32Å; W287-R299 VanDerWaalsContact CD1-NE 3.3Å; W287-R299 HydrophobicContact CD2-CG 3.86Å; W287-R299 HydrophobicContact CE3-CG 4.16Å; W287-R299 HydrophobicContact CG-CG 4.45Å; W287-R299 VanDerWaalsContact CG-NE 3.32Å; W287-R299 HydrophobicContact CH2-CG 4.13Å; W287-R299 HydrophobicContact CZ2-CG 3.8Å; W287-R299 HydrophobicContact CZ3-CG 4.3Å; A295-R299 WeakPolarHBondContact O-CB 3.29Å; A295-R299 VanDerWaalsContact O-CG 3.26Å; A295-R299 WeakPolarHBondContact O-CG 3.17Å; A295-R299 PolarHBondContact O-N 2.92Å; A295-R299 VanDerWaalsContact O-N 3.15Å; E297-R299 VanDerWaalsContact C-N 3.34Å; E297-R299 PolarHBondContact O-N 3.37Å; R299-R301 PolarHBondContact O-N 3.03Å; R299-T302 VanDerWaalsContact O-CB 3.27Å; R299-T302 WeakPolarHBondContact O-CB 3.45Å; R299-T302 PolarHBondContact O-N 3.03Å; R299-T302 PolarHBondContact O-OG1 3.37Å
300A91.5Very high91.2Very high82 Ų8247.1 Ų47.168%0.67827%0.273SS*.Hα-helixtrans-62.8-21.4-179.400000113.7A296 E297 T302A296-A300 WeakPolarHBondContact O-CB 3.35Å; A296-A300 PolarHBondContact O-N 2.96Å; E297-A300 PolarHBondContact O-N 3.19Å; A300-T302 VanDerWaalsContact C-N 3.28Å
301R90.1Very high91Very high93 Ų9349.9 Ų49.935%0.35129%0.285SS..THydrogen-bonded Turntrans-74.6-15.6174-63.3175.9-172.2-1624.1113.7E250 R266 E297 L298 R299 A303E250-R301 IonicContact OE2-NH1 3.83Å; E250-R301 PolarHBondContact OE2-NH1 3.49Å; E250-R301 VanDerWaalsContact OE2-NH1 3.1Å; R266-R301 PolarHBondContact NH1-O 3.01Å; R266-R301 VanDerWaalsContact NH1-O 3.09Å; E297-R301 WeakPolarHBondContact O-CG 3.36Å; E297-R301 PolarHBondContact O-N 3.09Å; E297-R301 IonicContact OE1-CZ 2.88Å; E297-R301 IonicContact OE1-NE 2.7Å; E297-R301 IonicContact OE1-NH2 3.65Å; E297-R301 PolarHBondContact OE1-NH2 3.11Å; L298-R301 PolarHBondContact O-N 3.21Å; R299-R301 PolarHBondContact O-N 3.03Å; R301-A303 PolarHBondContact O-N 2.82Å
302T88.3Confident90.6Very high41 Ų4149.4 Ų49.425%0.25229%0.293SS..  trans-75.4117.8-174-45.30000110.3R299 A300 E306 W308R299-T302 VanDerWaalsContact O-CB 3.27Å; R299-T302 WeakPolarHBondContact O-CB 3.45Å; R299-T302 PolarHBondContact O-N 3.03Å; R299-T302 PolarHBondContact O-OG1 3.37Å; A300-T302 VanDerWaalsContact C-N 3.28Å; T302-E306 HydrophobicContact CG2-CB 4.05Å; T302-E306 VanDerWaalsContact CG2-O 3.24Å; T302-E306 WeakPolarHBondContact CG2-O 3.19Å; T302-W308 PolarHBondContact OG1-NE1 3.4Å
303A85Confident90.4Very high47 Ų4746.2 Ų46.239%0.38827%0.269SS..  trans-94.4176.717500000112.6R301 G305 E306R301-A303 PolarHBondContact O-N 2.82Å; A303-G305 PolarHBondContact O-N 3.35Å; A303-E306 HydrophobicContact CB-CG 4.24Å; A303-E306 WeakPolarHBondContact CB-OE2 3.4Å; A303-E306 PolarHBondContact N-OE2 3Å; A303-E306 WeakPolarHBondContact O-CB 3.45Å; A303-E306 PolarHBondContact O-N 2.79Å
304E81.8Confident90.1Very high111 Ų11141.1 Ų41.152%0.51924%0.238SC..THydrogen-bonded Turntrans-58.1128.3174.3-164-167.6160.400110.9K67 H142 G272 E306K67-E304 IonicContact NZ-OE1 3.85Å; K67-E304 PolarHBondContact NZ-OE1 3.15Å; K67-E304 IonicContact NZ-OE2 3.92Å; K67-E304 PolarHBondContact NZ-OE2 2.92Å; H142-E304 IonicContact CD2-OE2 3.53Å; G272-E304 WeakPolarHBondContact O-CG 3.21Å; E304-E306 VanDerWaalsContact C-N 3.29Å; E304-E306 PolarHBondContact O-N 2.78Å
305G82.9Confident89.7Confident4 Ų442.1 Ų42.14%0.04124%0.243CC..THydrogen-bonded Turntrans79.25-176.500000115.3N269 A303N269-G305 PolarHBondContact N-O 2.95Å; A303-G305 PolarHBondContact O-N 3.35Å
306E90Very high89.2Confident7 Ų745.1 Ų45.13%0.03327%0.265CS..EExtended strand (participates in β ladder)trans-105.7152.7176.9-59.6-177.1166.800112.3R266 I267 R268 T302 A303 E304R266-E306 WeakPolarHBondContact CD-OE2 3.31Å; R266-E306 HydrophobicContact CG-CB 4.42Å; R266-E306 IonicContact CZ-OE2 2.66Å; R266-E306 IonicContact NE-OE2 3.67Å; R266-E306 IonicContact NH1-OE1 2.7Å; R266-E306 IonicContact NH1-OE2 3.1Å; R266-E306 PolarHBondContact NH1-OE2 2.98Å; I267-E306 CarbonylContact O-C 3.13Å; I267-E306 WeakPolarHBondContact O-CA 3.44Å; R268-E306 HydrophobicContact CB-CG 3.93Å; R268-E306 HydrophobicContact CG-CG 3.93Å; R268-E306 IonicContact CZ-OE1 3.32Å; R268-E306 IonicContact NH1-OE1 2.67Å; R268-E306 PolarHBondContact NH1-OE1 2.96Å; T302-E306 HydrophobicContact CG2-CB 4.05Å; T302-E306 VanDerWaalsContact CG2-O 3.24Å; T302-E306 WeakPolarHBondContact CG2-O 3.19Å; A303-E306 HydrophobicContact CB-CG 4.24Å; A303-E306 WeakPolarHBondContact CB-OE2 3.4Å; A303-E306 PolarHBondContact N-OE2 3Å; A303-E306 WeakPolarHBondContact O-CB 3.45Å; A303-E306 PolarHBondContact O-N 2.79Å; E304-E306 VanDerWaalsContact C-N 3.29Å; E304-E306 PolarHBondContact O-N 2.78Å
307F91.1Very high88.7Confident4 Ų444.8 Ų44.82%0.01825%0.253CS..EExtended strand (participates in β ladder)trans-152.1158.2176.654.6-84000111.1L246 R266 I267 N269 W276 L309L246-F307 HydrophobicContact CD2-CE1 4Å; L246-F307 HydrophobicContact CD2-CZ 3.78Å; R266-F307 CarbonylContact C-O 3.54Å; R266-F307 WeakPolarHBondContact CA-O 3.34Å; I267-F307 HydrophobicContact CB-CD2 4.29Å; I267-F307 HydrophobicContact CB-CE1 4.26Å; I267-F307 HydrophobicContact CB-CE2 3.89Å; I267-F307 HydrophobicContact CB-CZ 3.87Å; I267-F307 HydrophobicContact CG1-CE2 4.32Å; I267-F307 HydrophobicContact CG2-CE1 4.16Å; I267-F307 HydrophobicContact CG2-CE2 4.21Å; I267-F307 HydrophobicContact CG2-CZ 3.74Å; I267-F307 PolarHBondContact N-O 3.07Å; I267-F307 PolarHBondContact O-N 3.24Å; N269-F307 HydrophobicContact CB-CE1 4.46Å; W276-F307 HydrophobicContact CB-CB 4.26Å; W276-F307 HydrophobicContact CB-CD1 4.03Å; W276-F307 HydrophobicContact CB-CD2 3.42Å; W276-F307 VanDerWaalsContact CB-CD2 3.42Å; W276-F307 HydrophobicContact CB-CE1 4.19Å; W276-F307 HydrophobicContact CB-CE2 3.57Å; W276-F307 HydrophobicContact CB-CG 3.65Å; W276-F307 HydrophobicContact CB-CZ 3.97Å; W276-F307 AromaticContact CD1-CD2 3.87Å; W276-F307 HydrophobicContact CD2-CD2 4.11Å; W276-F307 AromaticContact CD2-CE2 3.56Å; W276-F307 HydrophobicContact CD2-CE2 3.56Å; W276-F307 HydrophobicContact CD2-CZ 4.16Å; W276-F307 AromaticContact CE3-CE2 3.82Å; W276-F307 HydrophobicContact CE3-CE2 3.82Å; W276-F307 AromaticContact CE3-CZ 3.99Å; W276-F307 HydrophobicContact CE3-CZ 3.99Å; W276-F307 AromaticContact CG-CD2 3.47Å; W276-F307 HydrophobicContact CG-CD2 3.47Å; W276-F307 VanDerWaalsContact CG-CD2 3.47Å; W276-F307 AromaticContact CG-CE2 3.42Å; W276-F307 HydrophobicContact CG-CE2 3.42Å; W276-F307 VanDerWaalsContact CG-CE2 3.42Å; W276-F307 HydrophobicContact CG-CG 4.21Å; W276-F307 HydrophobicContact CG-CZ 4.16Å; F307-L309 HydrophobicContact CD2-CD2 4.07Å; F307-L309 HydrophobicContact CE2-CD2 3.68Å
308W93.4Very high88.3Confident1 Ų139.9 Ų39.90%0.00423%0.231CC..EExtended strand (participates in β ladder)trans-102.9153.3173.2-67.789.7000110.6E250 L252 L264 L265 R266 W280 W287 L298 T302E250-W308 VanDerWaalsContact CD-CH2 3.43Å; E250-W308 HydrophobicContact CG-CH2 3.57Å; E250-W308 HydrophobicContact CG-CZ2 4.35Å; E250-W308 HydrophobicContact CG-CZ3 4.08Å; E250-W308 WeakPolarHBondContact OE1-CH2 3.37Å; E250-W308 WeakPolarHBondContact OE1-CZ2 3.43Å; L252-W308 HydrophobicContact CD1-CH2 4.02Å; L264-W308 HydrophobicContact CB-CE3 3.75Å; L264-W308 HydrophobicContact CB-CZ3 3.92Å; L265-W308 VanDerWaalsContact C-CE3 3.48Å; L265-W308 WeakPolarHBondContact O-CA 3.36Å; R266-W308 HydrophobicContact CB-CD2 3.88Å; R266-W308 HydrophobicContact CB-CE3 3.88Å; R266-W308 HydrophobicContact CB-CH2 3.9Å; R266-W308 HydrophobicContact CB-CZ2 3.87Å; R266-W308 HydrophobicContact CB-CZ3 3.9Å; R266-W308 HydrophobicContact CG-CD2 4.33Å; R266-W308 HydrophobicContact CG-CZ2 4.29Å; W280-W308 HydrophobicContact CB-CB 3.76Å; W280-W308 WeakPolarHBondContact CB-O 3.13Å; W287-W308 HydrophobicContact CH2-CB 4.11Å; W287-W308 AromaticContact CH2-CD1 3.63Å; W287-W308 HydrophobicContact CH2-CD2 4.31Å; W287-W308 AromaticContact CH2-CG 3.77Å; W287-W308 HydrophobicContact CH2-CG 3.77Å; W287-W308 HydrophobicContact CZ2-CB 4.09Å; W287-W308 AromaticContact CZ2-CD1 3.8Å; W287-W308 HydrophobicContact CZ2-CG 4.07Å; L298-W308 HydrophobicContact CB-CZ2 4.45Å; L298-W308 HydrophobicContact CD2-CH2 4.03Å; L298-W308 HydrophobicContact CD2-CZ2 4.11Å; L298-W308 PolarHBondContact O-NE1 3Å; T302-W308 PolarHBondContact OG1-NE1 3.4Å
309L92.8Very high87.8Confident0 Ų040.3 Ų40.30%023%0.233CC..EExtended strand (participates in β ladder)trans-154.2162.1171.656.489.9000109.2L264 L265 I267 F307 E313 F314 F318L264-L309 CarbonylContact C-O 3.41Å; L264-L309 WeakPolarHBondContact CA-O 3.38Å; L265-L309 HydrophobicContact CB-CD1 4.14Å; L265-L309 HydrophobicContact CD1-CD1 4.23Å; L265-L309 PolarHBondContact N-O 3.45Å; L265-L309 PolarHBondContact O-N 3.45Å; L265-L309 VanDerWaalsContact O-N 3.08Å; I267-L309 HydrophobicContact CG1-CD2 3.71Å; I267-L309 HydrophobicContact CG1-CG 4.2Å; F307-L309 HydrophobicContact CD2-CD2 4.07Å; F307-L309 HydrophobicContact CE2-CD2 3.68Å; L309-E313 HydrophobicContact CB-CB 4.42Å; L309-E313 HydrophobicContact CB-CG 4.33Å; L309-F314 HydrophobicContact CD1-CB 3.31Å; L309-F314 HydrophobicContact CD1-CD2 3.72Å; L309-F314 HydrophobicContact CD1-CG 3.9Å; L309-F318 HydrophobicContact CD2-CE2 3.89Å; L309-F318 HydrophobicContact CD2-CZ 4.43Å
310D92.6Very high87.5Confident35 Ų3537.4 Ų37.419%0.18722%0.222CC..EExtended strand (participates in β ladder)trans-91.2162.4173.960.357.1000112.7V262 R263 L264 W280 A312 E313 F314V262-D310 HydrophobicContact CG2-CB 3.8Å; R263-D310 CarbonylContact O-C 3.46Å; R263-D310 VanDerWaalsContact O-CA 3.27Å; R263-D310 WeakPolarHBondContact O-CA 3.41Å; L264-D310 HydrophobicContact CD2-CB 4.05Å; W280-D310 PolarHBondContact NE1-OD2 2.7Å; D310-A312 PolarHBondContact O-N 2.67Å; D310-A312 WeakPolarHBondContact OD1-CB 3.39Å; D310-A312 PolarHBondContact OD1-N 3.15Å; D310-E313 PolarHBondContact O-N 3.22Å; D310-E313 WeakPolarHBondContact OD1-CB 3.29Å; D310-E313 PolarHBondContact OD1-N 2.91Å; D310-F314 WeakPolarHBondContact O-CB 3.08Å; D310-F314 PolarHBondContact O-N 2.67Å
311E89.5Confident87.4Confident62 Ų6233.5 Ų33.529%0.2919%0.19SC..Hα-helixtrans-58.7-29.7-177.4-177.3174.5-137.700113.5R263 L265 F314 T315R263-E311 HydrophobicContact CB-CB 3.98Å; R263-E311 HydrophobicContact CG-CB 4.23Å; R263-E311 IonicContact NH1-OE1 3.1Å; R263-E311 PolarHBondContact NH1-OE1 3.32Å; R263-E311 IonicContact NH1-OE2 2.84Å; R263-E311 PolarHBondContact O-N 2.77Å; L265-E311 HydrophobicContact CD1-CB 4.08Å; E311-F314 WeakPolarHBondContact O-CB 3.22Å; E311-T315 WeakPolarHBondContact O-CB 3.38Å; E311-T315 PolarHBondContact O-N 2.73Å; E311-T315 PolarHBondContact O-OG1 3.31Å
312A87.8Confident87.4Confident74 Ų7429.3 Ų29.361%0.61218%0.175SC*.Hα-helixtrans-71.2-47.617700000110.7D310 F314 T315 S316D310-A312 PolarHBondContact O-N 2.67Å; D310-A312 WeakPolarHBondContact OD1-CB 3.39Å; D310-A312 PolarHBondContact OD1-N 3.15Å; A312-F314 VanDerWaalsContact C-N 3.32Å; A312-F314 PolarHBondContact O-N 2.95Å; A312-T315 PolarHBondContact O-N 2.82Å; A312-S316 WeakPolarHBondContact O-CB 3.22Å; A312-S316 PolarHBondContact O-N 3.08Å; A312-S316 VanDerWaalsContact O-N 3.12Å; A312-S316 PolarHBondContact O-OG 3.43Å
313E87.3Confident87.7Confident34 Ų3427.3 Ų27.316%0.15916%0.163CC..Hα-helixtrans-58.3-46.4172.3-171.9172.4-167.500110.3W276 L309 D310 T315 S316 Q317W276-E313 HydrophobicContact CZ2-CG 4.28Å; W276-E313 PolarHBondContact NE1-OE1 2.99Å; L309-E313 HydrophobicContact CB-CB 4.42Å; L309-E313 HydrophobicContact CB-CG 4.33Å; D310-E313 PolarHBondContact O-N 3.22Å; D310-E313 WeakPolarHBondContact OD1-CB 3.29Å; D310-E313 PolarHBondContact OD1-N 2.91Å; E313-T315 PolarHBondContact O-N 2.85Å; E313-S316 PolarHBondContact O-N 2.94Å; E313-S316 PolarHBondContact O-OG 2.83Å; E313-Q317 HydrophobicContact CG-CG 4.24Å; E313-Q317 WeakPolarHBondContact O-CB 3.5Å; E313-Q317 WeakPolarHBondContact O-CG 3.46Å; E313-Q317 PolarHBondContact O-N 2.82Å; E313-Q317 VanDerWaalsContact O-N 3.09Å
314F88.2Confident88.1Confident0 Ų025.3 Ų25.30%015%0.146CC..Hα-helixtrans-53.3-54.1178-170.4-121.2000112.6L188 L212 C228 V248 L265 I267 L309 D310 E311 A312 S316 Q317 F318 I321L188-F314 HydrophobicContact CD1-CE1 4.42Å; L212-F314 HydrophobicContact CD2-CD1 4.48Å; L212-F314 HydrophobicContact CD2-CE1 4.04Å; C228-F314 HydrophobicContact CB-CE2 3.84Å; C228-F314 HydrophobicContact CB-CZ 3.97Å; V248-F314 HydrophobicContact CG2-CE2 4.37Å; V248-F314 HydrophobicContact CG2-CZ 4.16Å; L265-F314 HydrophobicContact CD1-CB 4.26Å; L265-F314 HydrophobicContact CD1-CG 4.43Å; L265-F314 HydrophobicContact CD2-CD1 3.79Å; L265-F314 HydrophobicContact CD2-CD2 4.08Å; L265-F314 HydrophobicContact CD2-CE1 3.78Å; L265-F314 HydrophobicContact CD2-CE2 4.14Å; L265-F314 HydrophobicContact CD2-CG 3.92Å; L265-F314 HydrophobicContact CD2-CZ 3.99Å; I267-F314 HydrophobicContact CD1-CD2 4.42Å; I267-F314 HydrophobicContact CD1-CE2 3.99Å; L309-F314 HydrophobicContact CD1-CB 3.31Å; L309-F314 HydrophobicContact CD1-CD2 3.72Å; L309-F314 HydrophobicContact CD1-CG 3.9Å; D310-F314 WeakPolarHBondContact O-CB 3.08Å; D310-F314 PolarHBondContact O-N 2.67Å; E311-F314 WeakPolarHBondContact O-CB 3.22Å; A312-F314 VanDerWaalsContact C-N 3.32Å; A312-F314 PolarHBondContact O-N 2.95Å; F314-S316 VanDerWaalsContact C-N 3.25Å; F314-S316 PolarHBondContact O-N 2.84Å; F314-Q317 PolarHBondContact O-N 2.8Å; F314-F318 AromaticContact CD2-CD2 3.23Å; F314-F318 HydrophobicContact CD2-CD2 3.23Å; F314-F318 AromaticContact CD2-CE2 3.51Å; F314-F318 HydrophobicContact CD2-CE2 3.51Å; F314-F318 HydrophobicContact CD2-CG 4.27Å; F314-F318 AromaticContact CE2-CD2 3.51Å; F314-F318 HydrophobicContact CE2-CD2 3.51Å; F314-F318 AromaticContact CE2-CE2 3.89Å; F314-F318 HydrophobicContact CE2-CE2 3.89Å; F314-F318 HydrophobicContact CE2-CG 4.18Å; F314-F318 HydrophobicContact CG-CD2 4.06Å; F314-F318 VanDerWaalsContact O-CD2 3.3Å; F314-F318 WeakPolarHBondContact O-CD2 3.26Å; F314-F318 PolarHBondContact O-N 3.28Å; F314-F318 VanDerWaalsContact O-N 3.07Å; F314-I321 HydrophobicContact CE1-CD1 3.35Å; F314-I321 HydrophobicContact CE1-CG1 4.27Å; F314-I321 HydrophobicContact CZ-CD1 3.54Å; F314-I321 HydrophobicContact CZ-CG1 4.04Å
315T85.4Confident88.7Confident57 Ų5720.1 Ų20.135%0.3512%0.122SC..Hα-helixtrans-67.5-29.6-175.4-52.20000111.7E311 A312 E313E311-T315 WeakPolarHBondContact O-CB 3.38Å; E311-T315 PolarHBondContact O-N 2.73Å; E311-T315 PolarHBondContact O-OG1 3.31Å; A312-T315 PolarHBondContact O-N 2.82Å; E313-T315 PolarHBondContact O-N 2.85Å
316S83.9Confident89.3Confident65 Ų6520 Ų2046%0.45512%0.12SC..Hα-helixtrans-75.4-30.3177.7740000113.6A312 E313 F314A312-S316 WeakPolarHBondContact O-CB 3.22Å; A312-S316 PolarHBondContact O-N 3.08Å; A312-S316 VanDerWaalsContact O-N 3.12Å; A312-S316 PolarHBondContact O-OG 3.43Å; E313-S316 PolarHBondContact O-N 2.94Å; E313-S316 PolarHBondContact O-OG 2.83Å; F314-S316 VanDerWaalsContact C-N 3.25Å; F314-S316 PolarHBondContact O-N 2.84Å
317Q82.5Confident89.5Confident48 Ų4820.1 Ų20.122%0.22412%0.121CC..Hα-helixtrans-99.6-35.9-168-63.9-67.2-43.300113.3W276 E313 F314W276-Q317 HydrophobicContact CH2-CB 3.63Å; W276-Q317 HydrophobicContact CH2-CG 3.63Å; W276-Q317 HydrophobicContact CZ2-CB 4.07Å; W276-Q317 HydrophobicContact CZ2-CG 3.64Å; E313-Q317 HydrophobicContact CG-CG 4.24Å; E313-Q317 WeakPolarHBondContact O-CB 3.5Å; E313-Q317 WeakPolarHBondContact O-CG 3.46Å; E313-Q317 PolarHBondContact O-N 2.82Å; E313-Q317 VanDerWaalsContact O-N 3.09Å; F314-Q317 PolarHBondContact O-N 2.8Å
318F85.8Confident89.3Confident1 Ų120.3 Ų20.30%0.00412%0.124CC..  trans-95.1148.3-178.9-60.7-74.8000111.3L188 C228 T230 L246 W276 L309 F314L188-F318 WeakPolarHBondContact CB-O 3.37Å; L188-F318 HydrophobicContact CD1-CB 3.5Å; L188-F318 WeakPolarHBondContact CD1-O 3.23Å; C228-F318 HydrophobicContact CB-CB 4.17Å; C228-F318 HydrophobicContact CB-CD1 3.84Å; C228-F318 HydrophobicContact CB-CD2 4.46Å; C228-F318 HydrophobicContact CB-CE1 4.43Å; C228-F318 HydrophobicContact CB-CG 3.88Å; T230-F318 HydrophobicContact CG2-CD1 3.56Å; T230-F318 HydrophobicContact CG2-CE1 3.85Å; T230-F318 HydrophobicContact CG2-CG 4.48Å; L246-F318 HydrophobicContact CD1-CE1 3.75Å; W276-F318 HydrophobicContact CZ3-CZ 4.28Å; L309-F318 HydrophobicContact CD2-CE2 3.89Å; L309-F318 HydrophobicContact CD2-CZ 4.43Å; F314-F318 AromaticContact CD2-CD2 3.23Å; F314-F318 HydrophobicContact CD2-CD2 3.23Å; F314-F318 AromaticContact CD2-CE2 3.51Å; F314-F318 HydrophobicContact CD2-CE2 3.51Å; F314-F318 HydrophobicContact CD2-CG 4.27Å; F314-F318 AromaticContact CE2-CD2 3.51Å; F314-F318 HydrophobicContact CE2-CD2 3.51Å; F314-F318 AromaticContact CE2-CE2 3.89Å; F314-F318 HydrophobicContact CE2-CE2 3.89Å; F314-F318 HydrophobicContact CE2-CG 4.18Å; F314-F318 HydrophobicContact CG-CD2 4.06Å; F314-F318 VanDerWaalsContact O-CD2 3.3Å; F314-F318 WeakPolarHBondContact O-CD2 3.26Å; F314-F318 PolarHBondContact O-N 3.28Å; F314-F318 VanDerWaalsContact O-N 3.07Å
319D82.1Confident89Confident13 Ų1329.4 Ų29.47%0.0716%0.163CC..  trans-94.5-40.6-177.8-73.5-90.9000112.5L188 R189 S229 T230 H231L188-D319 WeakPolarHBondContact CB-O 3.48Å; L188-D319 PolarHBondContact N-O 3.22Å; R189-D319 WeakPolarHBondContact CD-OD1 3.21Å; R189-D319 VanDerWaalsContact CZ-CG 3.46Å; R189-D319 IonicContact CZ-OD1 3.64Å; R189-D319 IonicContact CZ-OD2 2.82Å; R189-D319 IonicContact NE-OD1 3.64Å; R189-D319 PolarHBondContact NE-OD1 3.41Å; R189-D319 IonicContact NH1-OD1 3.88Å; R189-D319 PolarHBondContact NH1-OD1 3Å; R189-D319 IonicContact NH1-OD2 3.91Å; R189-D319 IonicContact NH2-OD1 2.7Å; R189-D319 IonicContact NH2-OD2 3.26Å; S229-D319 PolarHBondContact O-N 2.79Å; T230-D319 WeakPolarHBondContact CA-OD2 3.46Å; H231-D319 HydrophobicContact CB-CB 4.44Å; H231-D319 WeakPolarHBondContact CD2-CB 3.49Å; H231-D319 IonicContact CD2-OD1 2.74Å; H231-D319 PolarHBondContact N-OD2 2.87Å
320D84.8Confident88.6Confident6 Ų633.9 Ų33.93%0.03219%0.187CC..EExtended strand (participates in β ladder)trans-143.9154.7-173.9-68.7-73.5000112R185 W186 C228 S229 H231R185-D320 HydrophobicContact CG-CB 4.1Å; R185-D320 IonicContact CZ-OD2 3.91Å; R185-D320 IonicContact NE-OD1 3.23Å; R185-D320 PolarHBondContact NE-OD1 3.38Å; R185-D320 IonicContact NE-OD2 3.26Å; R185-D320 PolarHBondContact NE-OD2 2.88Å; R185-D320 IonicContact NH2-OD2 3.34Å; R185-D320 PolarHBondContact NH2-OD2 3.45Å; W186-D320 CarbonylContact O-C 3.54Å; W186-D320 VanDerWaalsContact O-CA 3.3Å; W186-D320 WeakPolarHBondContact O-CA 3.48Å; C228-D320 WeakPolarHBondContact CA-O 3.4Å; S229-D320 PolarHBondContact N-O 2.81Å; S229-D320 VanDerWaalsContact N-O 3.07Å; S229-D320 PolarHBondContact O-N 3.47Å; H231-D320 IonicContact CD2-OD2 3.38Å; H231-D320 IonicContact CE1-OD2 2.72Å; H231-D320 IonicContact NE2-OD2 3.67Å; H231-D320 PolarHBondContact NE2-OD2 3.3Å
321I89.3Confident88.4Confident1 Ų133.7 Ų33.71%0.00519%0.194CC..EExtended strand (participates in β ladder)trans-120.6136.9172-69.9175.3000109.7R185 W186 L188 L212 L226 S227 C228 F314 V323R185-I321 CarbonylContact C-O 2.97Å; R185-I321 VanDerWaalsContact CA-O 3.29Å; R185-I321 WeakPolarHBondContact CA-O 3.49Å; W186-I321 PolarHBondContact N-O 2.85Å; W186-I321 PolarHBondContact O-N 3.33Å; L188-I321 HydrophobicContact CD1-CD1 4.01Å; L188-I321 HydrophobicContact CD1-CG1 3.84Å; L188-I321 HydrophobicContact CD2-CD1 3.61Å; L188-I321 HydrophobicContact CD2-CG1 4.1Å; L188-I321 HydrophobicContact CG-CD1 4.18Å; L188-I321 HydrophobicContact CG-CG1 4.14Å; L212-I321 HydrophobicContact CD1-CD1 3.71Å; L212-I321 HydrophobicContact CD2-CD1 3.4Å; L212-I321 VanDerWaalsContact CD2-CD1 3.4Å; L212-I321 HydrophobicContact CG-CD1 4.06Å; L226-I321 HydrophobicContact CD2-CG2 3.86Å; S227-I321 CarbonylContact O-C 3.5Å; S227-I321 WeakPolarHBondContact O-CA 3.32Å; C228-I321 HydrophobicContact CB-CG1 4.34Å; F314-I321 HydrophobicContact CE1-CD1 3.35Å; F314-I321 HydrophobicContact CE1-CG1 4.27Å; F314-I321 HydrophobicContact CZ-CD1 3.54Å; F314-I321 HydrophobicContact CZ-CG1 4.04Å; I321-V323 HydrophobicContact CG2-CG2 3.92Å
322T92.1Very high88.5Confident4 Ų433 Ų333%0.02519%0.192CC..EExtended strand (participates in β ladder)trans-101.4125.8166.3-59.10000109.3V171 L175 A183 E184 L226 S227V171-T322 HydrophobicContact CB-CG2 4.32Å; V171-T322 HydrophobicContact CG1-CG2 4.31Å; L175-T322 HydrophobicContact CD1-CG2 3.9Å; A183-T322 HydrophobicContact CB-CG2 4.41Å; E184-T322 CarbonylContact O-C 3.37Å; E184-T322 WeakPolarHBondContact O-CA 3.12Å; L226-T322 WeakPolarHBondContact CA-O 3.43Å; S227-T322 PolarHBondContact N-O 2.89Å; S227-T322 PolarHBondContact O-N 2.79Å
323V92.9Very high88.9Confident0 Ų029.8 Ų29.80%016%0.164CC..EExtended strand (participates in β ladder)trans-109.5115.8176.1-169.30000109.3A183 E184 W186 L217 A225 L226 I321 V336A183-V323 CarbonylContact C-O 3.24Å; A183-V323 VanDerWaalsContact CA-O 3.25Å; A183-V323 WeakPolarHBondContact CA-O 3.33Å; E184-V323 PolarHBondContact N-O 3.14Å; E184-V323 PolarHBondContact O-N 3.01Å; W186-V323 HydrophobicContact CD2-CG2 3.78Å; W186-V323 HydrophobicContact CE3-CG2 3.9Å; W186-V323 HydrophobicContact CG-CG2 4.37Å; W186-V323 HydrophobicContact CH2-CG2 4.19Å; W186-V323 HydrophobicContact CZ2-CG2 4.06Å; W186-V323 HydrophobicContact CZ3-CG2 4.1Å; L217-V323 HydrophobicContact CD1-CG1 4.38Å; L217-V323 HydrophobicContact CD1-CG2 4.34Å; L217-V323 HydrophobicContact CD2-CG1 4.01Å; A225-V323 CarbonylContact O-C 3.59Å; A225-V323 WeakPolarHBondContact O-CA 3.49Å; L226-V323 HydrophobicContact CD2-CB 4.12Å; L226-V323 HydrophobicContact CD2-CG1 3.99Å; L226-V323 HydrophobicContact CD2-CG2 3.66Å; I321-V323 HydrophobicContact CG2-CG2 3.92Å; V323-V336 HydrophobicContact CG1-CG1 4.01Å
324G94.6Very high89.2Confident4 Ų430.2 Ų30.24%0.04117%0.166CC..EExtended strand (participates in β ladder)trans-90.8130.2168.400000110.8A225A225-G324 PolarHBondContact N-O 3.24Å; A225-G324 PolarHBondContact O-N 2.79Å
325Y94.6Very high89.4Confident2 Ų230.2 Ų30.21%0.00817%0.166CC..PPolyproline II helixtrans-66.8135.1178.4-81.1-118.1000110.5V182 E184 L333 K334 V336 Y337 L384V182-Y325 HydrophobicContact CB-CD2 4.02Å; V182-Y325 HydrophobicContact CB-CG 4.21Å; V182-Y325 HydrophobicContact CG1-CD2 4.03Å; V182-Y325 HydrophobicContact CG1-CE2 4.07Å; V182-Y325 WeakPolarHBondContact O-CB 3.3Å; V182-Y325 WeakPolarHBondContact O-CD2 3.46Å; V182-Y325 PolarHBondContact O-N 3.38Å; E184-Y325 HydrophobicContact CG-CE2 3.97Å; E184-Y325 WeakPolarHBondContact OE1-CE2 3.37Å; E184-Y325 VanDerWaalsContact OE1-CZ 3.31Å; E184-Y325 PolarHBondContact OE1-OH 2.84Å; Y325-L333 VanDerWaalsContact CB-CD1 3.48Å; Y325-L333 HydrophobicContact CD1-CD2 4.02Å; Y325-L333 HydrophobicContact CD1-CG 4.19Å; Y325-L333 HydrophobicContact CG-CD1 4.45Å; Y325-L333 HydrophobicContact CG-CD2 4.33Å; Y325-L333 HydrophobicContact CG-CG 4.43Å; Y325-K334 VanDerWaalsContact CD1-O 3.26Å; Y325-K334 WeakPolarHBondContact CD1-O 3.19Å; Y325-V336 HydrophobicContact CD1-CG1 3.82Å; Y325-V336 HydrophobicContact CD1-CG2 4.44Å; Y325-V336 HydrophobicContact CD2-CG1 3.86Å; Y325-V336 HydrophobicContact CD2-CG2 4.5Å; Y325-V336 HydrophobicContact CE1-CB 4.33Å; Y325-V336 HydrophobicContact CE1-CG1 4.03Å; Y325-V336 HydrophobicContact CE1-CG2 3.79Å; Y325-V336 HydrophobicContact CE2-CG1 4.1Å; Y325-V336 HydrophobicContact CE2-CG2 3.89Å; Y325-V336 HydrophobicContact CG-CG1 3.71Å; Y325-V336 VanDerWaalsContact CZ-CG2 3.49Å; Y325-Y337 WeakPolarHBondContact OH-CE2 3.49Å; Y325-L384 HydrophobicContact CD1-CD1 3.93Å; Y325-L384 HydrophobicContact CE1-CD1 3.14Å; Y325-L384 HydrophobicContact CE2-CD1 4.31Å; Y325-L384 VanDerWaalsContact OH-CD1 3.3Å; Y325-L384 WeakPolarHBondContact OH-CD1 3.47Å
326P94.4Very high89.6Confident1 Ų127.5 Ų27.51%0.00615%0.149CC..PPolyproline II helixtrans-61.8145.7176.8-15.122.8000112.3V220 E223 C224 K334V220-P326 HydrophobicContact CB-CG 3.76Å; V220-P326 HydrophobicContact CG1-CG 3.87Å; V220-P326 HydrophobicContact CG2-CG 4.48Å; E223-P326 HydrophobicContact CB-CB 3.69Å; E223-P326 HydrophobicContact CB-CG 3.96Å; C224-P326 HydrophobicContact CB-CG 3.96Å; P326-K334 HydrophobicContact CB-CB 4.15Å; P326-K334 HydrophobicContact CB-CD 4.44Å; P326-K334 HydrophobicContact CG-CB 4.29Å; P326-K334 PolarHBondContact O-N 3.34Å
327I94Very high89.6Confident11 Ų1126.9 Ų26.96%0.05614%0.137CC..BIsolated β-bridgetrans-118121.5170.7-59.5-177.6000108.4N86 L89 T179 L332 L333N86-I327 PolarHBondContact ND2-O 3.23Å; L89-I327 HydrophobicContact CD1-CB 4.18Å; L89-I327 HydrophobicContact CD1-CD1 4.28Å; L89-I327 HydrophobicContact CD2-CB 4.35Å; L89-I327 HydrophobicContact CD2-CD1 4.03Å; L89-I327 HydrophobicContact CD2-CG2 4.14Å; T179-I327 WeakPolarHBondContact O-CD1 3.33Å; I327-L332 WeakPolarHBondContact CA-O 3.49Å; I327-L333 HydrophobicContact CG1-CD1 3.93Å
328G88.3Confident89.9Confident7 Ų727.9 Ų27.97%0.07215%0.147CC..  trans-65.7168.4176.900000112.6D330 G331 L332G328-D330 WeakPolarHBondContact CA-OD1 3.48Å; G328-D330 PolarHBondContact O-N 3.14Å; G328-G331 PolarHBondContact O-N 2.97Å; G328-L332 PolarHBondContact N-O 3.41Å
329K86.1Confident90.1Very high192 Ų19229 Ų2984%0.83516%0.158SC*.THydrogen-bonded Turntrans-64.8-19.3177.4-63.7-178-179.5179.50113.3H88 G331H88-K329 PolarHBondContact CE1-O 3.06Å; H88-K329 PolarHBondContact ND1-O 3.23Å; K329-G331 VanDerWaalsContact C-N 3.26Å
330D85.3Confident90.5Very high94 Ų9431.2 Ų31.250%0.50317%0.173SC..THydrogen-bonded Turntrans-82-1.5172.6536.7000113G328 L332 L341G328-D330 WeakPolarHBondContact CA-OD1 3.48Å; G328-D330 PolarHBondContact O-N 3.14Å; D330-L332 VanDerWaalsContact C-N 3.27Å; D330-L332 HydrophobicContact CB-CG 4.43Å; D330-L332 PolarHBondContact O-N 3.11Å; D330-L332 WeakPolarHBondContact OD1-CB 3.49Å; D330-L332 PolarHBondContact OD1-N 3.01Å; D330-L332 VanDerWaalsContact OD1-N 3.12Å; D330-L341 WeakPolarHBondContact OD2-CD2 3.5Å
331G87.8Confident91Very high32 Ų3233.4 Ų33.433%0.3318%0.184SC..SBendtrans77.79.7-178.300000114G328 K329G328-G331 PolarHBondContact O-N 2.97Å; K329-G331 VanDerWaalsContact C-N 3.26Å
332L92.3Very high91.2Very high47 Ų4733.4 Ų33.425%0.24618%0.184CC..  trans-91.1145179.8-63.4176.5000111.5I327 G328 D330 L341 T343I327-L332 WeakPolarHBondContact CA-O 3.49Å; G328-L332 PolarHBondContact N-O 3.41Å; D330-L332 VanDerWaalsContact C-N 3.27Å; D330-L332 HydrophobicContact CB-CG 4.43Å; D330-L332 PolarHBondContact O-N 3.11Å; D330-L332 WeakPolarHBondContact OD1-CB 3.49Å; D330-L332 PolarHBondContact OD1-N 3.01Å; D330-L332 VanDerWaalsContact OD1-N 3.12Å; L332-L341 HydrophobicContact CB-CD1 3.73Å; L332-L341 HydrophobicContact CB-CD2 4.44Å; L332-L341 HydrophobicContact CB-CG 4.06Å; L332-L341 HydrophobicContact CD1-CD2 3.9Å; L332-L341 HydrophobicContact CD1-CG 4.24Å; L332-T343 HydrophobicContact CD1-CG2 4.37Å
333L95.1Very high91.4Very high6 Ų636.3 Ų36.33%0.03120%0.202CC..EExtended strand (participates in β ladder)trans-75.9139.9179.3-159.670.8000110.3V182 Y325 I327 L342 F484V182-L333 HydrophobicContact CB-CD2 4.16Å; V182-L333 HydrophobicContact CG2-CD2 3.76Å; Y325-L333 VanDerWaalsContact CB-CD1 3.48Å; Y325-L333 HydrophobicContact CD1-CD2 4.02Å; Y325-L333 HydrophobicContact CD1-CG 4.19Å; Y325-L333 HydrophobicContact CG-CD1 4.45Å; Y325-L333 HydrophobicContact CG-CD2 4.33Å; Y325-L333 HydrophobicContact CG-CG 4.43Å; I327-L333 HydrophobicContact CG1-CD1 3.93Å; L333-L342 HydrophobicContact CD2-CD1 4.24Å; L333-L342 WeakPolarHBondContact O-CB 3.27Å; L333-L342 PolarHBondContact O-N 3.23Å; L333-F484 HydrophobicContact CB-CD1 4.11Å; L333-F484 HydrophobicContact CD2-CB 4.32Å; L333-F484 HydrophobicContact CD2-CD1 3.99Å; L333-F484 HydrophobicContact CD2-CD2 4.09Å; L333-F484 HydrophobicContact CD2-CE1 4.28Å; L333-F484 HydrophobicContact CD2-CE2 4.36Å; L333-F484 HydrophobicContact CD2-CG 3.88Å; L333-F484 HydrophobicContact CD2-CZ 4.45Å
334K94.3Very high91.4Very high44 Ų4439.3 Ų39.319%0.19122%0.216CC..EExtended strand (participates in β ladder)trans-106139.8168.8-68-179.7175175.40110.7E223 Y325 P326 V336 T340 L341E223-K334 IonicContact OE1-NZ 3.73Å; E223-K334 PolarHBondContact OE1-NZ 3.29Å; E223-K334 IonicContact OE2-NZ 3.78Å; E223-K334 PolarHBondContact OE2-NZ 3.44Å; Y325-K334 VanDerWaalsContact CD1-O 3.26Å; Y325-K334 WeakPolarHBondContact CD1-O 3.19Å; P326-K334 HydrophobicContact CB-CB 4.15Å; P326-K334 HydrophobicContact CB-CD 4.44Å; P326-K334 HydrophobicContact CG-CB 4.29Å; P326-K334 PolarHBondContact O-N 3.34Å; K334-V336 PolarHBondContact O-N 3.03Å; K334-T340 CarbonylContact C-O 3.55Å; K334-T340 WeakPolarHBondContact CA-O 3.44Å; K334-L341 HydrophobicContact CG-CD1 3.59Å
335S91.1Very high91.3Very high0 Ų042.6 Ų42.60%024%0.238CC..  trans-65.9130.4174175.40000110.8V220 Y337 T338 G339 T340 E382V220-S335 WeakPolarHBondContact CG1-O 3.44Å; S335-Y337 PolarHBondContact O-N 2.91Å; S335-Y337 PolarHBondContact OG-N 3.27Å; S335-Y337 VanDerWaalsContact OG-N 3.07Å; S335-T338 WeakPolarHBondContact CB-OG1 3.39Å; S335-T338 PolarHBondContact OG-N 3.49Å; S335-G339 VanDerWaalsContact O-CA 3.22Å; S335-G339 WeakPolarHBondContact O-CA 3.35Å; S335-G339 PolarHBondContact O-N 2.83Å; S335-T340 PolarHBondContact N-O 2.79Å; S335-E382 WeakPolarHBondContact CB-OE2 3.34Å; S335-E382 PolarHBondContact OG-OE1 3.31Å; S335-E382 PolarHBondContact OG-OE2 3.47Å
336V90.1Very high91.1Very high0 Ų045.4 Ų45.40%025%0.251CS..THydrogen-bonded Turntrans-71.5-13.4171.7-60.10000113W186 L217 V220 V323 Y325 K334W186-V336 HydrophobicContact CZ2-CG2 4.36Å; L217-V336 HydrophobicContact CD2-CB 3.81Å; L217-V336 HydrophobicContact CD2-CG2 4.45Å; V220-V336 HydrophobicContact CG2-CB 4.24Å; V220-V336 HydrophobicContact CG2-CG1 4.42Å; V323-V336 HydrophobicContact CG1-CG1 4.01Å; Y325-V336 HydrophobicContact CD1-CG1 3.82Å; Y325-V336 HydrophobicContact CD1-CG2 4.44Å; Y325-V336 HydrophobicContact CD2-CG1 3.86Å; Y325-V336 HydrophobicContact CD2-CG2 4.5Å; Y325-V336 HydrophobicContact CE1-CB 4.33Å; Y325-V336 HydrophobicContact CE1-CG1 4.03Å; Y325-V336 HydrophobicContact CE1-CG2 3.79Å; Y325-V336 HydrophobicContact CE2-CG1 4.1Å; Y325-V336 HydrophobicContact CE2-CG2 3.89Å; Y325-V336 HydrophobicContact CG-CG1 3.71Å; Y325-V336 VanDerWaalsContact CZ-CG2 3.49Å; K334-V336 PolarHBondContact O-N 3.03Å
337Y85.1Confident91.1Very high51 Ų5149.1 Ų49.120%0.227%0.268CS..THydrogen-bonded Turntrans-92.8-38.1-177.6-58.2-71.8000112.6E184 W186 K210 Y325 S335 C456E184-Y337 PolarHBondContact OE2-OH 2.59Å; W186-Y337 HydrophobicContact CZ2-CE1 4.21Å; K210-Y337 VanDerWaalsContact NZ-CZ 3.34Å; K210-Y337 PolarHBondContact NZ-OH 2.89Å; Y325-Y337 WeakPolarHBondContact OH-CE2 3.49Å; S335-Y337 PolarHBondContact O-N 2.91Å; S335-Y337 PolarHBondContact OG-N 3.27Å; S335-Y337 VanDerWaalsContact OG-N 3.07Å; Y337-C456 HydrophobicContact CD2-CB 4.04Å; Y337-C456 HydrophobicContact CE2-CB 3.65Å
338T88.2Confident90.9Very high69 Ų6951 Ų5142%0.42328%0.278SS..THydrogen-bonded Turntrans-117.7-13.2-173.667.80000113.2S335 T340 E382S335-T338 WeakPolarHBondContact CB-OG1 3.39Å; S335-T338 PolarHBondContact OG-N 3.49Å; T338-T340 WeakPolarHBondContact CB-OG1 3.31Å; T338-T340 PolarHBondContact O-N 3.03Å; T338-T340 WeakPolarHBondContact OG1-CB 3.48Å; T338-T340 PolarHBondContact OG1-N 3.03Å; T338-T340 VanDerWaalsContact OG1-N 3.11Å; T338-T340 PolarHBondContact OG1-OG1 2.79Å; T338-E382 WeakPolarHBondContact CG2-OE2 3.16Å; T338-E382 PolarHBondContact OG1-OE2 3.35Å
339G89.4Confident91Very high24 Ų2454.4 Ų54.425%0.24731%0.306CS..  trans70.90.6-169.400000113.7C219 S335C219-G339 PolarHBondContact SG-N 3.06Å; S335-G339 VanDerWaalsContact O-CA 3.22Å; S335-G339 WeakPolarHBondContact O-CA 3.35Å; S335-G339 PolarHBondContact O-N 2.83Å
340T91.3Very high91.3Very high61 Ų6147 Ų4737%0.37428%0.278SS..  trans-70.7138.1-176.6-54.10000110.7K334 S335 T338K334-T340 CarbonylContact C-O 3.55Å; K334-T340 WeakPolarHBondContact CA-O 3.44Å; S335-T340 PolarHBondContact N-O 2.79Å; T338-T340 WeakPolarHBondContact CB-OG1 3.31Å; T338-T340 PolarHBondContact O-N 3.03Å; T338-T340 WeakPolarHBondContact OG1-CB 3.48Å; T338-T340 PolarHBondContact OG1-N 3.03Å; T338-T340 VanDerWaalsContact OG1-N 3.11Å; T338-T340 PolarHBondContact OG1-OG1 2.79Å
341L94.2Very high91.6Very high51 Ų5149.4 Ų49.427%0.26728%0.28SS..EExtended strand (participates in β ladder)trans-72.6128.2172.7-165.368.7000110.3D330 L332 K334 T343D330-L341 WeakPolarHBondContact OD2-CD2 3.5Å; L332-L341 HydrophobicContact CB-CD1 3.73Å; L332-L341 HydrophobicContact CB-CD2 4.44Å; L332-L341 HydrophobicContact CB-CG 4.06Å; L332-L341 HydrophobicContact CD1-CD2 3.9Å; L332-L341 HydrophobicContact CD1-CG 4.24Å; K334-L341 HydrophobicContact CG-CD1 3.59Å; L341-T343 HydrophobicContact CD2-CG2 4.12Å; L341-T343 HydrophobicContact CG-CG2 4.28Å; L341-T343 PolarHBondContact O-N 3.12Å
342L95.1Very high91.8Very high2 Ų248 Ų481%0.0127%0.265CS..EExtended strand (participates in β ladder)trans-92.888178.3-54.3-179.6000108.8L333 H344 L384 F484 S485L333-L342 HydrophobicContact CD2-CD1 4.24Å; L333-L342 WeakPolarHBondContact O-CB 3.27Å; L333-L342 PolarHBondContact O-N 3.23Å; L342-H344 VanDerWaalsContact C-N 3.31Å; L342-H344 PolarHBondContact O-N 2.78Å; L342-L384 HydrophobicContact CD1-CB 4.19Å; L342-F484 HydrophobicContact CB-CB 4.01Å; L342-F484 HydrophobicContact CD1-CB 3.61Å; L342-F484 HydrophobicContact CG-CB 4.45Å; L342-S485 CarbonylContact C-O 3.59Å; L342-S485 VanDerWaalsContact C-O 3.24Å; L342-S485 WeakPolarHBondContact CA-O 3.43Å
343T94.8Very high91.6Very high65 Ų6548.8 Ų48.840%0.39927%0.268SS..  trans-74-16.7-171.152.70000114.5L332 L341 S485L332-T343 HydrophobicContact CD1-CG2 4.37Å; L341-T343 HydrophobicContact CD2-CG2 4.12Å; L341-T343 HydrophobicContact CG-CG2 4.28Å; L341-T343 PolarHBondContact O-N 3.12Å; T343-S485 PolarHBondContact N-O 3.35Å
344H92.4Very high91.1Very high63 Ų6355.7 Ų55.729%0.29230%0.298SS..EExtended strand (participates in β ladder)trans-111.9130.9178.7-63.2-79.8000110.6L342 F484 S485 S487L342-H344 VanDerWaalsContact C-N 3.31Å; L342-H344 PolarHBondContact O-N 2.78Å; H344-F484 CarbonylContact O-C 3.21Å; H344-F484 VanDerWaalsContact O-CA 3.28Å; H344-F484 WeakPolarHBondContact O-CA 3.28Å; H344-S485 PolarHBondContact N-O 3.36Å; H344-S485 PolarHBondContact O-N 2.99Å; H344-S487 PolarHBondContact CD2-O 3.46Å
345S93.2Very high90.2Very high72 Ų7255.9 Ų55.950%0.50331%0.312SS..EExtended strand (participates in β ladder)trans-134.5140.8176.364.60000112.6V483S345-V483 CarbonylContact C-O 3.49Å; S345-V483 VanDerWaalsContact CA-O 3.23Å; S345-V483 WeakPolarHBondContact CA-O 3.37Å
346H91.6Very high89.7Confident62 Ų6258.1 Ų58.129%0.28732%0.323SS..EExtended strand (participates in β ladder)trans-139148.4175.6-56.4-68.9000110.2R482 V483 T489 L491H346-R482 CarbonylContact O-C 3.55Å; H346-R482 VanDerWaalsContact O-CA 3.31Å; H346-R482 WeakPolarHBondContact O-CA 3.38Å; H346-V483 HydrophobicContact CB-CB 4.41Å; H346-V483 PolarHBondContact N-O 3.22Å; H346-V483 PolarHBondContact O-N 3.36Å; H346-T489 PolarHBondContact CD2-OG1 3.4Å; H346-T489 PolarHBondContact NE2-O 3Å; H346-T489 PolarHBondContact NE2-OG1 2.89Å; H346-L491 HydrophobicContact CB-CB 3.73Å; H346-L491 HydrophobicContact CB-CD2 3.95Å
347Q93.1Very high89.4Confident78 Ų7858.6 Ų58.636%0.36433%0.326SS..EExtended strand (participates in β ladder)trans-142.2142.1171.667.5-179.215.400111.7G118 L480 I481 R482G118-Q347 PolarHBondContact O-NE2 2.84Å; G118-Q347 PolarHBondContact O-OE1 3.24Å; Q347-L480 HydrophobicContact CB-CD1 4.1Å; Q347-L480 HydrophobicContact CB-CD2 4.49Å; Q347-L480 HydrophobicContact CB-CG 4.37Å; Q347-L480 HydrophobicContact CG-CD1 4.47Å; Q347-I481 CarbonylContact C-O 3.56Å; Q347-I481 WeakPolarHBondContact CA-O 3.01Å; Q347-R482 HydrophobicContact CB-CG 4.16Å
348L90.6Very high89.5Confident52 Ų5256.5 Ų56.527%0.27232%0.319SS..EExtended strand (participates in β ladder)trans-138.4126.9176.5-70179.6000110.9F373 I481 L491 A493L348-F373 HydrophobicContact CB-CD1 4.45Å; L348-F373 HydrophobicContact CB-CE1 4.16Å; L348-F373 HydrophobicContact CD1-CD1 3.87Å; L348-F373 HydrophobicContact CD1-CE1 4.25Å; L348-I481 PolarHBondContact N-O 3.04Å; L348-I481 PolarHBondContact O-N 2.96Å; L348-L491 HydrophobicContact CB-CD2 4.26Å; L348-L491 HydrophobicContact CD1-CD2 3.89Å; L348-L491 HydrophobicContact CD1-CG 3.67Å; L348-L491 HydrophobicContact CG-CD2 3.83Å; L348-L491 HydrophobicContact CG-CG 4.16Å; L348-A493 HydrophobicContact CD1-CB 4.38Å
349A90.3Very high89.2Confident78 Ų7853.2 Ų53.265%0.64530%0.299SS*.EExtended strand (participates in β ladder)trans-85.6142.7176.100000111.3F479 L480A349-F479 WeakPolarHBondContact CA-O 3.12Å; A349-L480 HydrophobicContact CB-CD1 4.14Å
350S91.4Very high89Confident35 Ų3552 Ų5225%0.24529%0.287CS..EExtended strand (participates in β ladder)trans-156.2-173.1175.4-170.70000111.1F479S350-F479 VanDerWaalsContact CB-CZ 3.46Å; S350-F479 PolarHBondContact N-O 3.11Å; S350-F479 PolarHBondContact O-N 3.3Å; S350-F479 VanDerWaalsContact O-O 3.09Å
351R92.2Very high88.8Confident146 Ų14649.6 Ų49.655%0.55127%0.272SS*.EExtended strand (participates in β ladder)trans-152.5144-176.357.4-177.383.21514.1112I353 S357 A477 R478R351-I353 HydrophobicContact CB-CG1 4.43Å; R351-I353 HydrophobicContact CG-CD1 3.85Å; R351-I353 HydrophobicContact CG-CG1 3.66Å; R351-S357 PolarHBondContact O-OG 2.93Å; R351-A477 CarbonylContact C-O 3.44Å; R351-A477 WeakPolarHBondContact CA-O 3.34Å; R351-R478 HydrophobicContact CB-CG 4.32Å
352W91.8Very high88.3Confident3 Ų350.8 Ų50.81%0.01127%0.273CS..EExtended strand (participates in β ladder)trans-86121.6162.1-60.8-75000108.4S357 A358 L387 Q389 I418 P468 T470 A475 E476 A477 F479W352-S357 WeakPolarHBondContact CA-OG 3.3Å; W352-A358 HydrophobicContact CB-CB 4Å; W352-L387 HydrophobicContact CH2-CD1 4.27Å; W352-L387 HydrophobicContact CH2-CD2 4.15Å; W352-L387 HydrophobicContact CH2-CG 4.46Å; W352-L387 HydrophobicContact CZ2-CD1 4.48Å; W352-L387 HydrophobicContact CZ2-CD2 4.17Å; W352-Q389 HydrophobicContact CZ3-CB 4.36Å; W352-I418 HydrophobicContact CH2-CB 4.16Å; W352-I418 HydrophobicContact CH2-CG2 3.41Å; W352-I418 VanDerWaalsContact CH2-CG2 3.41Å; W352-I418 HydrophobicContact CZ2-CG2 4.21Å; W352-I418 HydrophobicContact CZ3-CG2 3.77Å; W352-P468 HydrophobicContact CZ2-CB 3.92Å; W352-P468 PolarHBondContact NE1-O 3.32Å; W352-T470 HydrophobicContact CD2-CG2 3.73Å; W352-T470 HydrophobicContact CE3-CG2 3.8Å; W352-T470 HydrophobicContact CG-CG2 4.1Å; W352-T470 HydrophobicContact CH2-CG2 4.48Å; W352-T470 HydrophobicContact CZ2-CG2 4.41Å; W352-T470 HydrophobicContact CZ3-CG2 4.19Å; W352-A475 WeakPolarHBondContact CB-O 3.5Å; W352-E476 WeakPolarHBondContact O-CA 3.48Å; W352-A477 HydrophobicContact CE3-CB 3.83Å; W352-A477 HydrophobicContact CZ3-CB 4.08Å; W352-A477 PolarHBondContact N-O 2.88Å; W352-A477 PolarHBondContact O-N 3.29Å; W352-F479 AromaticContact CD2-CD1 3.63Å; W352-F479 HydrophobicContact CD2-CD1 3.63Å; W352-F479 AromaticContact CD2-CE1 3.7Å; W352-F479 HydrophobicContact CD2-CE1 3.7Å; W352-F479 AromaticContact CE2-CD1 3.78Å; W352-F479 AromaticContact CE2-CE1 3.64Å; W352-F479 AromaticContact CE3-CD1 3.47Å; W352-F479 HydrophobicContact CE3-CD1 3.47Å; W352-F479 VanDerWaalsContact CE3-CD1 3.47Å; W352-F479 HydrophobicContact CE3-CE1 4.06Å; W352-F479 HydrophobicContact CE3-CG 4.37Å; W352-F479 HydrophobicContact CG-CD1 4.44Å; W352-F479 HydrophobicContact CG-CE1 4.16Å; W352-F479 HydrophobicContact CH2-CB 3.99Å; W352-F479 AromaticContact CH2-CD1 3.69Å; W352-F479 HydrophobicContact CH2-CD1 3.69Å; W352-F479 HydrophobicContact CH2-CE1 4.32Å; W352-F479 AromaticContact CH2-CG 3.91Å; W352-F479 HydrophobicContact CH2-CG 3.91Å; W352-F479 AromaticContact CZ2-CD1 3.84Å; W352-F479 HydrophobicContact CZ2-CD1 3.84Å; W352-F479 AromaticContact CZ2-CE1 4Å; W352-F479 HydrophobicContact CZ2-CE1 4Å; W352-F479 HydrophobicContact CZ2-CG 4.29Å; W352-F479 HydrophobicContact CZ3-CB 3.83Å; W352-F479 AromaticContact CZ3-CD1 3.51Å; W352-F479 HydrophobicContact CZ3-CD1 3.51Å; W352-F479 HydrophobicContact CZ3-CE1 4.36Å; W352-F479 AromaticContact CZ3-CG 3.96Å; W352-F479 HydrophobicContact CZ3-CG 3.96Å; W352-F479 AromaticContact NE1-CE1 3.98Å
353I88.2Confident87.5Confident63 Ų6357.9 Ų57.932%0.32331%0.312SS..  trans-116.9129.4-177.8-51.9174.6000108.1R351 G355 H356 S357 A358R351-I353 HydrophobicContact CB-CG1 4.43Å; R351-I353 HydrophobicContact CG-CD1 3.85Å; R351-I353 HydrophobicContact CG-CG1 3.66Å; I353-G355 PolarHBondContact O-N 2.5Å; I353-H356 HydrophobicContact CB-CB 4.27Å; I353-H356 HydrophobicContact CG2-CB 4.38Å; I353-H356 PolarHBondContact O-N 3.3Å; I353-H356 VanDerWaalsContact O-N 3.13Å; I353-S357 PolarHBondContact N-OG 2.93Å; I353-S357 PolarHBondContact O-N 3.13Å; I353-A358 WeakPolarHBondContact O-CB 3.38Å; I353-A358 PolarHBondContact O-N 2.86Å
354K84Confident86.7Confident150 Ų15056.3 Ų56.365%0.65230%0.302SS*.THydrogen-bonded Turntrans-59.5133.2-179.5-175.2173.8179.5178.40110.8H356 E476K354-H356 PolarHBondContact O-N 2.91Å; K354-E476 HydrophobicContact CB-CG 3.79Å; K354-E476 WeakPolarHBondContact CB-OE1 3.45Å; K354-E476 PolarHBondContact N-OE1 3.18Å
355G77.2Confident86.1Confident48 Ų4859.1 Ų59.150%0.49533%0.328SS..THydrogen-bonded Turntrans73.71.8179.800000115.4I353I353-G355 PolarHBondContact O-N 2.5Å
356H79.8Confident85.4Confident48 Ų4857.6 Ų57.622%0.22232%0.318CS..THydrogen-bonded Turntrans-128.9-65.2178.3-177.5-108.5000112.6I353 K354 S369 P499I353-H356 HydrophobicContact CB-CB 4.27Å; I353-H356 HydrophobicContact CG2-CB 4.38Å; I353-H356 PolarHBondContact O-N 3.3Å; I353-H356 VanDerWaalsContact O-N 3.13Å; K354-H356 PolarHBondContact O-N 2.91Å; H356-S369 WeakPolarHBondContact O-CB 3.33Å; H356-P499 VanDerWaalsContact CD2-CA 3.42Å; H356-P499 WeakPolarHBondContact CD2-CA 3.47Å; H356-P499 WeakPolarHBondContact CD2-CB 3.42Å; H356-P499 VanDerWaalsContact NE2-CA 3.3Å; H356-P499 WeakPolarHBondContact NE2-CA 3.37Å
357S83.9Confident85Confident10 Ų1055.1 Ų55.17%0.0731%0.306CS..THydrogen-bonded Turntrans-119.9-4.9-174.367.10000113.9R351 W352 I353 G359 S369 N370 P371R351-S357 PolarHBondContact O-OG 2.93Å; W352-S357 WeakPolarHBondContact CA-OG 3.3Å; I353-S357 PolarHBondContact N-OG 2.93Å; I353-S357 PolarHBondContact O-N 3.13Å; S357-G359 VanDerWaalsContact C-N 3.29Å; S357-G359 PolarHBondContact O-N 2.87Å; S357-S369 WeakPolarHBondContact CA-O 3.36Å; S357-N370 WeakPolarHBondContact O-CA 3.48Å; S357-N370 PolarHBondContact O-OD1 3.44Å; S357-P371 WeakPolarHBondContact O-CD 3.31Å
358A87.8Confident84.5Confident6 Ų654.4 Ų54.45%0.0531%0.309CS..  trans-82.970.6174.400000111W352 I353 G360 G474 A475W352-A358 HydrophobicContact CB-CB 4Å; I353-A358 WeakPolarHBondContact O-CB 3.38Å; I353-A358 PolarHBondContact O-N 2.86Å; A358-G360 VanDerWaalsContact C-N 3.34Å; A358-G360 PolarHBondContact O-N 2.87Å; A358-G474 PolarHBondContact O-N 2.95Å; A358-A475 WeakPolarHBondContact CB-O 3.12Å
359G81.5Confident84.2Confident0 Ų054.1 Ų54.10%031%0.312CS..  trans-76.7-13-17100000116S357 S366 Y367 S369 N370S357-G359 VanDerWaalsContact C-N 3.29Å; S357-G359 PolarHBondContact O-N 2.87Å; G359-S366 WeakPolarHBondContact CA-O 3.22Å; G359-S366 CarbonylContact O-C 3.54Å; G359-S366 WeakPolarHBondContact O-CB 3.32Å; G359-S366 PolarHBondContact O-OG 2.9Å; G359-Y367 PolarHBondContact O-N 3.46Å; G359-S369 WeakPolarHBondContact CA-OG 3.3Å; G359-N370 PolarHBondContact N-OD1 2.73Å
360G84.5Confident84.1Confident0 Ų050.5 Ų50.50%028%0.282CS..  trans76.7-169-175.700000113A358 Y367 N370 S469 T470A358-G360 VanDerWaalsContact C-N 3.34Å; A358-G360 PolarHBondContact O-N 2.87Å; G360-Y367 VanDerWaalsContact O-CD2 3.27Å; G360-Y367 WeakPolarHBondContact O-CD2 3.47Å; G360-N370 PolarHBondContact O-ND2 2.72Å; G360-S469 WeakPolarHBondContact O-CB 3.41Å; G360-T470 CarbonylContact C-O 3.54Å; G360-T470 VanDerWaalsContact CA-O 3.31Å; G360-T470 WeakPolarHBondContact CA-O 3.48Å
361S86.9Confident84.2Confident9 Ų949.6 Ų49.66%0.06328%0.275CS..SBendtrans-71.6170.5-178.570.90000112.8N363 T364 Y367 H447 T470 Y471S361-N363 PolarHBondContact O-N 3.33Å; S361-N363 VanDerWaalsContact O-N 3.08Å; S361-T364 VanDerWaalsContact O-CB 3.3Å; S361-T364 WeakPolarHBondContact O-CB 3.29Å; S361-T364 PolarHBondContact O-N 2.79Å; S361-T364 PolarHBondContact O-OG1 2.85Å; S361-Y367 WeakPolarHBondContact O-CB 3.22Å; S361-Y367 WeakPolarHBondContact O-CD2 3.41Å; S361-H447 VanDerWaalsContact CB-CE1 3.49Å; S361-H447 WeakPolarHBondContact CB-CE1 3.42Å; S361-T470 PolarHBondContact N-O 3.46Å; S361-Y471 WeakPolarHBondContact CB-O 3.44Å; S361-Y471 PolarHBondContact N-O 3.38Å
362R84.1Confident84.1Confident76 Ų7643.6 Ų43.629%0.28725%0.253SS..THydrogen-bonded Turntrans-55.6-26.6178.3-71.8-179.863.9119.76.7114T364 Y367 H421 L436 K438 P440R362-T364 PolarHBondContact O-N 2.83Å; R362-Y367 VanDerWaalsContact CA-CD2 3.49Å; R362-Y367 HydrophobicContact CB-CD2 4.41Å; R362-Y367 HydrophobicContact CB-CE2 4.42Å; R362-Y367 HydrophobicContact CG-CD1 4.31Å; R362-Y367 HydrophobicContact CG-CD2 4.1Å; R362-Y367 HydrophobicContact CG-CE1 3.91Å; R362-Y367 HydrophobicContact CG-CE2 3.66Å; R362-Y367 HydrophobicContact CG-CG 4.41Å; R362-Y367 VanDerWaalsContact N-CD2 3.33Å; R362-H421 WeakPolarHBondContact CD-NE2 3.17Å; R362-L436 PolarHBondContact NH2-O 3.23Å; R362-L436 VanDerWaalsContact NH2-O 3.14Å; R362-K438 PolarHBondContact NH2-O 3.06Å; R362-K438 VanDerWaalsContact NH2-O 3.12Å; R362-P440 VanDerWaalsContact NH1-CG 3.35Å
363N79.3Confident84.1Confident152 Ų15243.6 Ų43.681%0.81325%0.253SS*.THydrogen-bonded Turntrans-78.8-2.2-179.7-60.4-9.8000112.1S361S361-N363 PolarHBondContact O-N 3.33Å; S361-N363 VanDerWaalsContact O-N 3.08Å
364T76.5Confident84.3Confident31 Ų3141.2 Ų41.219%0.1924%0.24CC..SBendtrans-99.5137.5178.9-43.50000110.8S361 R362 S366 Y367 P473S361-T364 VanDerWaalsContact O-CB 3.3Å; S361-T364 WeakPolarHBondContact O-CB 3.29Å; S361-T364 PolarHBondContact O-N 2.79Å; S361-T364 PolarHBondContact O-OG1 2.85Å; R362-T364 PolarHBondContact O-N 2.83Å; T364-S366 VanDerWaalsContact CG2-OG 3.25Å; T364-S366 WeakPolarHBondContact CG2-OG 3.39Å; T364-S366 PolarHBondContact O-N 3.35Å; T364-Y367 VanDerWaalsContact O-CB 3.27Å; T364-Y367 WeakPolarHBondContact O-CB 3.35Å; T364-Y367 PolarHBondContact O-N 3.16Å; T364-P473 HydrophobicContact CG2-CB 3.93Å; T364-P473 HydrophobicContact CG2-CG 3.86Å
365S79.4Confident84.7Confident122 Ų12234 Ų3485%0.85321%0.209SC*.G310 helixtrans-57.6-30.8176.657.20000113.3Y367S365-Y367 VanDerWaalsContact C-N 3.3Å; S365-Y367 PolarHBondContact O-N 3.25Å
366S80.1Confident85.4Confident40 Ų4037.1 Ų37.128%0.2821%0.206SC..G310 helixtrans-80.22.7176.952.20000114.6G359 T364 S368 S369G359-S366 WeakPolarHBondContact CA-O 3.22Å; G359-S366 CarbonylContact O-C 3.54Å; G359-S366 WeakPolarHBondContact O-CB 3.32Å; G359-S366 PolarHBondContact O-OG 2.9Å; T364-S366 VanDerWaalsContact CG2-OG 3.25Å; T364-S366 WeakPolarHBondContact CG2-OG 3.39Å; T364-S366 PolarHBondContact O-N 3.35Å; S366-S368 PolarHBondContact O-N 2.64Å; S366-S368 VanDerWaalsContact O-N 3.07Å; S366-S369 WeakPolarHBondContact O-CB 3.46Å; S366-S369 PolarHBondContact O-N 2.84Å; S366-S369 PolarHBondContact O-OG 3.43Å
367Y82.9Confident86Confident11 Ų1135 Ų354%0.04320%0.196CC..G310 helixtrans-52.7-37.1-176.9-179.1-107000113.4G359 G360 S361 R362 T364 S365 S369 N370 H421 W423 L436 I467G359-Y367 PolarHBondContact O-N 3.46Å; G360-Y367 VanDerWaalsContact O-CD2 3.27Å; G360-Y367 WeakPolarHBondContact O-CD2 3.47Å; S361-Y367 WeakPolarHBondContact O-CB 3.22Å; S361-Y367 WeakPolarHBondContact O-CD2 3.41Å; R362-Y367 VanDerWaalsContact CA-CD2 3.49Å; R362-Y367 HydrophobicContact CB-CD2 4.41Å; R362-Y367 HydrophobicContact CB-CE2 4.42Å; R362-Y367 HydrophobicContact CG-CD1 4.31Å; R362-Y367 HydrophobicContact CG-CD2 4.1Å; R362-Y367 HydrophobicContact CG-CE1 3.91Å; R362-Y367 HydrophobicContact CG-CE2 3.66Å; R362-Y367 HydrophobicContact CG-CG 4.41Å; R362-Y367 VanDerWaalsContact N-CD2 3.33Å; T364-Y367 VanDerWaalsContact O-CB 3.27Å; T364-Y367 WeakPolarHBondContact O-CB 3.35Å; T364-Y367 PolarHBondContact O-N 3.16Å; S365-Y367 VanDerWaalsContact C-N 3.3Å; S365-Y367 PolarHBondContact O-N 3.25Å; Y367-S369 PolarHBondContact O-N 2.91Å; Y367-S369 VanDerWaalsContact O-N 3.15Å; Y367-N370 WeakPolarHBondContact CD2-ND2 3.12Å; Y367-N370 WeakPolarHBondContact O-CB 3.45Å; Y367-N370 PolarHBondContact O-N 3.07Å; Y367-N370 VanDerWaalsContact O-N 3.14Å; Y367-N370 PolarHBondContact O-ND2 2.66Å; Y367-H421 WeakPolarHBondContact OH-CB 3.25Å; Y367-H421 PolarHBondContact OH-ND1 2.77Å; Y367-W423 AromaticContact CE1-CH2 3.91Å; Y367-W423 HydrophobicContact CE1-CH2 3.91Å; Y367-W423 WeakPolarHBondContact OH-CH2 3.39Å; Y367-L436 HydrophobicContact CD1-CD1 4.27Å; Y367-L436 HydrophobicContact CE1-CD2 4.32Å; Y367-I467 HydrophobicContact CE1-CD1 4.32Å; Y367-I467 HydrophobicContact CE1-CG2 4.3Å; Y367-I467 HydrophobicContact CE2-CG2 4.35Å
368S83.1Confident86.3Confident62 Ų6237.1 Ų37.143%0.43421%0.21SC..G310 helixtrans-65.6-12178.966.30000114S366 K372S366-S368 PolarHBondContact O-N 2.64Å; S366-S368 VanDerWaalsContact O-N 3.07Å; S368-K372 WeakPolarHBondContact O-CE 3.43Å; S368-K372 PolarHBondContact O-NZ 3.02Å
369S82.8Confident86.5Confident47 Ų4742.6 Ų42.633%0.32924%0.235SC..G310 helixtrans-84-15.3174.870.20000113.8H356 S357 G359 S366 Y367H356-S369 WeakPolarHBondContact O-CB 3.33Å; S357-S369 WeakPolarHBondContact CA-O 3.36Å; G359-S369 WeakPolarHBondContact CA-OG 3.3Å; S366-S369 WeakPolarHBondContact O-CB 3.46Å; S366-S369 PolarHBondContact O-N 2.84Å; S366-S369 PolarHBondContact O-OG 3.43Å; Y367-S369 PolarHBondContact O-N 2.91Å; Y367-S369 VanDerWaalsContact O-N 3.15Å
370N89.6Confident87.1Confident2 Ų246.4 Ų46.41%0.01126%0.258CS..SBendtrans-54.9150.4178.1-76.9-65.4000112.1S357 G359 G360 Y367 K372 I467S357-N370 WeakPolarHBondContact O-CA 3.48Å; S357-N370 PolarHBondContact O-OD1 3.44Å; G359-N370 PolarHBondContact N-OD1 2.73Å; G360-N370 PolarHBondContact O-ND2 2.72Å; Y367-N370 WeakPolarHBondContact CD2-ND2 3.12Å; Y367-N370 WeakPolarHBondContact O-CB 3.45Å; Y367-N370 PolarHBondContact O-N 3.07Å; Y367-N370 VanDerWaalsContact O-N 3.14Å; Y367-N370 PolarHBondContact O-ND2 2.66Å; N370-K372 PolarHBondContact O-NZ 2.99Å; N370-I467 HydrophobicContact CB-CG2 3.64Å
371P92.6Very high87.5Confident15 Ų1546.9 Ų46.910%0.09726%0.263CS..  trans-53.3148174.7-26.737.3000111.6S357 F373 P468 F479S357-P371 WeakPolarHBondContact O-CD 3.31Å; P371-F373 HydrophobicContact CB-CE2 3.73Å; P371-F373 HydrophobicContact CB-CZ 4.17Å; P371-P468 HydrophobicContact CB-CG 4.4Å; P371-P468 WeakPolarHBondContact O-CD 3.35Å; P371-F479 HydrophobicContact CB-CZ 3.96Å; P371-F479 HydrophobicContact CG-CE1 4.04Å; P371-F479 HydrophobicContact CG-CZ 3.88Å
372K90.7Very high87.9Confident20 Ų2047.4 Ų47.49%0.08726%0.264CS..  trans-128.8140.9-177.9-81.9155.8-162.251.90109.9S368 N370 L432 L465 L466 I467 L494S368-K372 WeakPolarHBondContact O-CE 3.43Å; S368-K372 PolarHBondContact O-NZ 3.02Å; N370-K372 PolarHBondContact O-NZ 2.99Å; K372-L432 HydrophobicContact CD-CD1 4.34Å; K372-L432 HydrophobicContact CD-CD2 4.26Å; K372-L432 VanDerWaalsContact CE-CD2 3.44Å; K372-L465 HydrophobicContact CB-CD1 3.96Å; K372-L465 HydrophobicContact CG-CD1 4.11Å; K372-L465 HydrophobicContact CG-CD2 4.43Å; K372-L466 WeakPolarHBondContact CA-O 3.44Å; K372-I467 HydrophobicContact CG-CD1 4Å; K372-I467 HydrophobicContact CG-CG1 3.88Å; K372-L494 HydrophobicContact CB-CB 3.76Å; K372-L494 HydrophobicContact CB-CD2 3.83Å; K372-L494 HydrophobicContact CB-CG 4.44Å; K372-L494 HydrophobicContact CD-CD2 3.88Å; K372-L494 HydrophobicContact CG-CD2 4.46Å; K372-L494 WeakPolarHBondContact O-CB 3.42Å; K372-L494 PolarHBondContact O-N 2.7Å
373F91.5Very high88.4Confident3 Ų343.8 Ų43.81%0.01325%0.251CS..EExtended strand (participates in β ladder)trans-133.4135.2178.9-55-100000110.1L348 P371 L466 P468 F479 I481 L491 S492 A493L348-F373 HydrophobicContact CB-CD1 4.45Å; L348-F373 HydrophobicContact CB-CE1 4.16Å; L348-F373 HydrophobicContact CD1-CD1 3.87Å; L348-F373 HydrophobicContact CD1-CE1 4.25Å; P371-F373 HydrophobicContact CB-CE2 3.73Å; P371-F373 HydrophobicContact CB-CZ 4.17Å; F373-L466 HydrophobicContact CB-CB 4.21Å; F373-L466 PolarHBondContact N-O 3.12Å; F373-L466 PolarHBondContact O-N 2.86Å; F373-P468 HydrophobicContact CD2-CG 4.18Å; F373-P468 HydrophobicContact CE2-CG 3.69Å; F373-F479 AromaticContact CE2-CE2 3.97Å; F373-F479 HydrophobicContact CE2-CE2 3.97Å; F373-F479 HydrophobicContact CE2-CZ 4.07Å; F373-F479 AromaticContact CZ-CE2 3.9Å; F373-F479 HydrophobicContact CZ-CE2 3.9Å; F373-F479 HydrophobicContact CZ-CZ 4.09Å; F373-I481 HydrophobicContact CD2-CD1 3.52Å; F373-I481 HydrophobicContact CE2-CD1 3.69Å; F373-I481 HydrophobicContact CG-CD1 4.07Å; F373-I481 HydrophobicContact CZ-CD1 4.34Å; F373-L491 HydrophobicContact CB-CD1 4.11Å; F373-S492 CarbonylContact C-O 3.52Å; F373-S492 VanDerWaalsContact CA-O 3.3Å; F373-S492 WeakPolarHBondContact CA-O 3.45Å; F373-A493 HydrophobicContact CD1-CB 3.91Å; F373-A493 HydrophobicContact CE1-CB 3.89Å
374W91.3Very high89.2Confident13 Ų1336.6 Ų36.65%0.04921%0.212CC..EExtended strand (participates in β ladder)trans-85.2125.4169.6-79.4120.9000109.7V425 F430 L465 L491 S492 L651W374-V425 HydrophobicContact CH2-CB 4.08Å; W374-V425 HydrophobicContact CH2-CG1 4.01Å; W374-V425 HydrophobicContact CH2-CG2 3.68Å; W374-V425 HydrophobicContact CZ3-CB 3.94Å; W374-V425 HydrophobicContact CZ3-CG1 4.36Å; W374-V425 HydrophobicContact CZ3-CG2 3.51Å; W374-F430 AromaticContact CH2-CE1 3.49Å; W374-F430 HydrophobicContact CH2-CE1 3.49Å; W374-F430 VanDerWaalsContact CH2-CE1 3.49Å; W374-F430 AromaticContact CH2-CZ 3.62Å; W374-F430 HydrophobicContact CH2-CZ 3.62Å; W374-F430 AromaticContact CZ2-CE1 3.67Å; W374-F430 HydrophobicContact CZ2-CE1 3.67Å; W374-F430 AromaticContact CZ2-CZ 3.68Å; W374-F430 HydrophobicContact CZ2-CZ 3.68Å; W374-L465 HydrophobicContact CZ3-CB 4.2Å; W374-L491 CarbonylContact O-C 3.58Å; W374-L491 WeakPolarHBondContact O-CA 3.46Å; W374-S492 PolarHBondContact N-O 3.36Å; W374-S492 PolarHBondContact O-N 3.34Å; W374-L651 HydrophobicContact CH2-CD1 3.94Å; W374-L651 HydrophobicContact CZ2-CD1 4.42Å; W374-L651 HydrophobicContact CZ3-CD1 4.12Å
375L92.4Very high90.2Very high0 Ų035.1 Ų35.10%020%0.203CC..EExtended strand (participates in β ladder)trans-110.6117.5165.5171.364.9000108.3V377 V383 V385 M422 L459 Y464 L466 V483 T489 S490L375-V377 HydrophobicContact CD2-CG2 4.42Å; L375-V377 HydrophobicContact CG-CG2 4.23Å; L375-V383 HydrophobicContact CD2-CG1 3.97Å; L375-V385 HydrophobicContact CD2-CG2 4.37Å; L375-M422 HydrophobicContact CD2-CE 4.44Å; L375-L459 HydrophobicContact CD2-CD1 4.19Å; L375-Y464 PolarHBondContact N-O 3.3Å; L375-Y464 PolarHBondContact O-N 3.21Å; L375-L466 HydrophobicContact CB-CD1 3.93Å; L375-L466 HydrophobicContact CB-CG 4.22Å; L375-L466 HydrophobicContact CD2-CD1 4.36Å; L375-V483 HydrophobicContact CD1-CG1 3.9Å; L375-V483 HydrophobicContact CD1-CG2 4.38Å; L375-T489 HydrophobicContact CD1-CG2 4.25Å; L375-S490 CarbonylContact C-O 3.5Å; L375-S490 WeakPolarHBondContact CA-O 3.41Å
376R93Very high91.1Very high113 Ų11329.3 Ų29.343%0.42616%0.163SC..EExtended strand (participates in β ladder)trans-97.3129.6169.5-175.9-177.4173.8-177.1-4.2108.6G462 Y463 T489 S490R376-G462 WeakPolarHBondContact CA-O 3.29Å; R376-Y463 HydrophobicContact CB-CD1 4.14Å; R376-Y463 HydrophobicContact CB-CE1 4.02Å; R376-Y463 HydrophobicContact CG-CD1 4.25Å; R376-Y463 HydrophobicContact CG-CE1 3.86Å; R376-Y463 HydrophobicContact CG-CE2 4.37Å; R376-T489 CarbonylContact O-C 3.53Å; R376-T489 WeakPolarHBondContact O-CA 3.35Å; R376-T489 WeakPolarHBondContact O-CB 3.48Å; R376-S490 WeakPolarHBondContact CB-OG 3.3Å; R376-S490 PolarHBondContact N-O 2.92Å; R376-S490 PolarHBondContact O-N 3.22Å
377V92.3Very high91.9Very high3 Ų327.4 Ų27.42%0.01815%0.149CC..EExtended strand (participates in β ladder)trans-109.4121.1172.1-179.20000107.2L375 E379 V383 L459 P461 G462 Y464 T489L375-V377 HydrophobicContact CD2-CG2 4.42Å; L375-V377 HydrophobicContact CG-CG2 4.23Å; V377-E379 WeakPolarHBondContact CG1-O 3.37Å; V377-V383 HydrophobicContact CG2-CG2 4.18Å; V377-L459 HydrophobicContact CG1-CB 4.43Å; V377-L459 HydrophobicContact CG2-CB 4.16Å; V377-L459 HydrophobicContact CG2-CD1 4.02Å; V377-P461 WeakPolarHBondContact O-CA 3.41Å; V377-G462 PolarHBondContact N-O 3.37Å; V377-G462 PolarHBondContact O-N 3.49Å; V377-Y464 HydrophobicContact CB-CD2 4.48Å; V377-Y464 HydrophobicContact CB-CE2 4.17Å; V377-Y464 HydrophobicContact CG2-CD2 3.84Å; V377-Y464 HydrophobicContact CG2-CE2 3.84Å; V377-T489 HydrophobicContact CG2-CG2 4.2Å
378C89.3Confident92.5Very high55 Ų5526.9 Ų26.937%0.37215%0.147SC..  trans-83.6-37.5-176.8-66.50000112.3P461 P488C378-P461 WeakPolarHBondContact O-CB 3.3Å; C378-P488 HydrophobicContact CB-CB 4.13Å; C378-P488 VanDerWaalsContact CB-O 3.29Å; C378-P488 WeakPolarHBondContact CB-O 3.08Å; C378-P488 PolarHBondContact N-O 3.5Å
379E91.9Very high93Very high120 Ų12024 Ų2456%0.56113%0.127SC*.SBendtrans-137.3152.5-175-68176.6-172.600109.9V377 G381 S487V377-E379 WeakPolarHBondContact CG1-O 3.37Å; E379-G381 PolarHBondContact O-N 2.84Å; E379-S487 WeakPolarHBondContact O-CB 3.25Å; E379-S487 PolarHBondContact O-OG 2.86Å
380T94.9Very high93.2Very high81 Ų8122.7 Ų22.750%0.49712%0.116SC..SBendtrans-57.4125.4177.3-48.70000109.5L459 E460 P461T380-L459 VanDerWaalsContact CA-O 3.32Å; T380-L459 WeakPolarHBondContact CA-O 3.48Å; T380-E460 WeakPolarHBondContact CG2-OE1 3.36Å; T380-E460 PolarHBondContact OG1-OE2 3.42Å; T380-P461 VanDerWaalsContact OG1-CD 3.29Å; T380-P461 WeakPolarHBondContact OG1-CD 3.48Å
381G92.8Very high92.6Very high10 Ų1026.9 Ų26.910%0.10313%0.131CC..EExtended strand (participates in β ladder)trans-169.3165.8-175.800000112.9E379 P458 L459E379-G381 PolarHBondContact O-N 2.84Å; G381-P458 WeakPolarHBondContact O-CA 3.39Å; G381-L459 PolarHBondContact N-O 3.4Å; G381-L459 VanDerWaalsContact N-O 3.12Å; G381-L459 PolarHBondContact O-N 2.87Å
382E94.7Very high91.2Very high19 Ų1931 Ų319%0.08915%0.148CC..EExtended strand (participates in β ladder)trans-73.3130.8172.4-169.8173.4-15300109.1S335 T338 C456 S485 S486S335-E382 WeakPolarHBondContact CB-OE2 3.34Å; S335-E382 PolarHBondContact OG-OE1 3.31Å; S335-E382 PolarHBondContact OG-OE2 3.47Å; T338-E382 WeakPolarHBondContact CG2-OE2 3.16Å; T338-E382 PolarHBondContact OG1-OE2 3.35Å; E382-C456 PolarHBondContact OE1-SG 3.28Å; E382-S485 WeakPolarHBondContact O-CA 3.37Å; E382-S485 WeakPolarHBondContact O-CB 3.39Å; E382-S485 PolarHBondContact O-OG 2.97Å; E382-S486 PolarHBondContact N-OG 3.43Å; E382-S486 PolarHBondContact O-N 3.17Å
383V95.9Very high89.3Confident1 Ų141.3 Ų41.31%0.00619%0.186CC..EExtended strand (participates in β ladder)trans-127.8120.5176.7-174.70000108.9L375 V377 V385 C456 R457 L459 V483 S485 T489L375-V383 HydrophobicContact CD2-CG1 3.97Å; V377-V383 HydrophobicContact CG2-CG2 4.18Å; V383-V385 HydrophobicContact CG1-CG2 4.06Å; V383-C456 WeakPolarHBondContact O-CA 3.37Å; V383-R457 PolarHBondContact N-O 3.12Å; V383-R457 PolarHBondContact O-N 3.09Å; V383-L459 HydrophobicContact CB-CD1 3.83Å; V383-L459 HydrophobicContact CB-CG 4.13Å; V383-L459 HydrophobicContact CG1-CD1 4.25Å; V383-L459 HydrophobicContact CG2-CB 4.1Å; V383-L459 HydrophobicContact CG2-CD1 3.86Å; V383-L459 HydrophobicContact CG2-CG 4.07Å; V383-V483 HydrophobicContact CG1-CG1 3.84Å; V383-S485 WeakPolarHBondContact CG2-OG 3.42Å; V383-T489 HydrophobicContact CG2-CG2 4.39Å
384L96.6Very high87.3Confident0 Ų046.4 Ų46.40%021%0.205CC..EExtended strand (participates in β ladder)trans-104.1124.2171.9-175.9153.2000108.9V182 Y325 L342 V454 L455 C456 V483 F484V182-L384 HydrophobicContact CG1-CD2 4.36Å; V182-L384 HydrophobicContact CG2-CD2 3.99Å; Y325-L384 HydrophobicContact CD1-CD1 3.93Å; Y325-L384 HydrophobicContact CE1-CD1 3.14Å; Y325-L384 HydrophobicContact CE2-CD1 4.31Å; Y325-L384 VanDerWaalsContact OH-CD1 3.3Å; Y325-L384 WeakPolarHBondContact OH-CD1 3.47Å; L342-L384 HydrophobicContact CD1-CB 4.19Å; L384-V454 HydrophobicContact CD1-CG1 3.91Å; L384-V454 HydrophobicContact CD2-CG1 3.79Å; L384-V454 HydrophobicContact CG-CG1 3.67Å; L384-L455 CarbonylContact C-O 3.48Å; L384-L455 WeakPolarHBondContact CA-O 3.44Å; L384-C456 HydrophobicContact CB-CB 4.44Å; L384-C456 HydrophobicContact CD1-CB 4.47Å; L384-C456 HydrophobicContact CG-CB 4.42Å; L384-V483 CarbonylContact O-C 3.48Å; L384-V483 WeakPolarHBondContact O-CA 3.39Å; L384-F484 HydrophobicContact CB-CB 4.36Å; L384-F484 HydrophobicContact CD2-CD2 3.63Å; L384-F484 HydrophobicContact CD2-CE2 4.32Å; L384-F484 HydrophobicContact CD2-CG 4.5Å; L384-F484 PolarHBondContact N-O 2.98Å; L384-F484 PolarHBondContact O-N 3.22Å
385V97.5Very high84.7Confident0 Ų050.8 Ų50.80%023%0.23CC..EExtended strand (participates in β ladder)trans-116.3122.2174.4-168.40000108.6L375 V383 L420 M422 L455 L466 I481 R482 V483L375-V385 HydrophobicContact CD2-CG2 4.37Å; V383-V385 HydrophobicContact CG1-CG2 4.06Å; V385-L420 HydrophobicContact CB-CD2 3.84Å; V385-L420 HydrophobicContact CG1-CD2 3.46Å; V385-L420 VanDerWaalsContact CG1-CD2 3.46Å; V385-M422 HydrophobicContact CG2-CE 3.83Å; V385-L455 PolarHBondContact N-O 3.22Å; V385-L455 PolarHBondContact O-N 3.07Å; V385-L466 HydrophobicContact CG1-CD1 4.02Å; V385-L466 HydrophobicContact CG2-CD2 4.46Å; V385-I481 HydrophobicContact CG1-CG2 4.28Å; V385-R482 CarbonylContact C-O 3.43Å; V385-R482 VanDerWaalsContact CA-O 3.31Å; V385-R482 WeakPolarHBondContact CA-O 3.01Å; V385-V483 HydrophobicContact CG1-CG2 4.06Å; V385-V483 HydrophobicContact CG2-CG2 4.2Å
386S96.7Very high82.3Confident0 Ų056.8 Ų56.80%027%0.266CS..EExtended strand (participates in β ladder)trans-110.7141.9172.9100.60000111.2E452 V453 I481 R482S386-E452 WeakPolarHBondContact CB-OE1 3.08Å; S386-E452 PolarHBondContact OG-OE1 2.79Å; S386-V453 WeakPolarHBondContact CA-O 3.43Å; S386-I481 CarbonylContact O-C 3.57Å; S386-I481 WeakPolarHBondContact O-CA 3.33Å; S386-R482 PolarHBondContact N-O 2.87Å; S386-R482 PolarHBondContact O-N 3.21Å; S386-R482 PolarHBondContact OG-NE 3.2Å
387L97.4Very high79.6Confident0 Ų059.7 Ų59.70%029%0.285CS..EExtended strand (participates in β ladder)trans-117.2106.8174.4173.365.4000108.1W352 I418 L420 E452 V453 P468 F479 I481W352-L387 HydrophobicContact CH2-CD1 4.27Å; W352-L387 HydrophobicContact CH2-CD2 4.15Å; W352-L387 HydrophobicContact CH2-CG 4.46Å; W352-L387 HydrophobicContact CZ2-CD1 4.48Å; W352-L387 HydrophobicContact CZ2-CD2 4.17Å; L387-I418 HydrophobicContact CD2-CB 4.23Å; L387-I418 HydrophobicContact CD2-CD1 4.21Å; L387-I418 HydrophobicContact CG-CD1 4.13Å; L387-L420 HydrophobicContact CD2-CB 4.37Å; L387-E452 VanDerWaalsContact O-CA 3.31Å; L387-E452 WeakPolarHBondContact O-CA 3.22Å; L387-V453 HydrophobicContact CB-CG2 3.83Å; L387-V453 HydrophobicContact CD2-CG2 4.09Å; L387-V453 HydrophobicContact CG-CG2 4.34Å; L387-V453 PolarHBondContact N-O 3.34Å; L387-V453 PolarHBondContact O-N 3.07Å; L387-P468 HydrophobicContact CD1-CB 3.56Å; L387-P468 HydrophobicContact CD1-CG 4.45Å; L387-P468 HydrophobicContact CD2-CB 3.54Å; L387-P468 HydrophobicContact CG-CB 4.18Å; L387-F479 HydrophobicContact CD1-CB 4.02Å; L387-F479 HydrophobicContact CD1-CD2 3.33Å; L387-F479 HydrophobicContact CD1-CE2 3.93Å; L387-F479 HydrophobicContact CD1-CG 3.83Å; L387-I481 HydrophobicContact CD1-CG1 3.83Å
388L95.8Very high76.8Confident1 Ų167.6 Ų67.61%0.00532%0.319CS..EExtended strand (participates in β ladder)trans-107.4117.4-177.1-175.7145.8000110.4W115 V176 R451 E452 F479 L480W115-L388 HydrophobicContact CH2-CD1 3.84Å; W115-L388 HydrophobicContact CZ3-CD1 3.84Å; V176-L388 HydrophobicContact CG1-CD1 3.98Å; L388-R451 CarbonylContact C-O 3.5Å; L388-R451 WeakPolarHBondContact CA-O 3.38Å; L388-E452 HydrophobicContact CB-CB 4.37Å; L388-E452 HydrophobicContact CB-CG 4.44Å; L388-E452 HydrophobicContact CD1-CB 4.42Å; L388-E452 HydrophobicContact CG-CB 4.43Å; L388-F479 CarbonylContact O-C 3.24Å; L388-F479 WeakPolarHBondContact O-CA 3.45Å; L388-F479 WeakPolarHBondContact O-CB 3.22Å; L388-L480 HydrophobicContact CB-CB 4.45Å; L388-L480 PolarHBondContact N-O 3.1Å; L388-L480 PolarHBondContact O-N 3.23Å
389Q93.9Very high74.5Confident1 Ų172.7 Ų72.71%0.00533%0.331CS..EExtended strand (participates in β ladder)trans-91.8156.2174.766.1179.4-49.100112.2W352 Y415 Q416 I418 E450 R451 R478W352-Q389 HydrophobicContact CZ3-CB 4.36Å; Q389-Y415 HydrophobicContact CG-CD1 3.71Å; Q389-Y415 HydrophobicContact CG-CE1 4.32Å; Q389-Y415 HydrophobicContact CG-CG 4.42Å; Q389-Q416 PolarHBondContact NE2-O 3.06Å; Q389-Q416 PolarHBondContact OE1-O 2.8Å; Q389-I418 HydrophobicContact CB-CD1 4.16Å; Q389-I418 HydrophobicContact CG-CD1 3.94Å; Q389-E450 PolarHBondContact NE2-O 3.36Å; Q389-R451 WeakPolarHBondContact CG-O 3.49Å; Q389-R451 PolarHBondContact N-O 2.85Å; Q389-R478 WeakPolarHBondContact CA-O 3.27Å
390H87.5Confident71.8Confident19 Ų1971.5 Ų71.59%0.08834%0.342CS..PPolyproline II helixtrans-92.5137.2179-60.649.5000109.6Q117 K392 R478Q117-H390 PolarHBondContact OE1-CD2 2.87Å; Q117-H390 PolarHBondContact OE1-NE2 2.64Å; H390-K392 PolarHBondContact O-N 3.47Å; H390-R478 HydrophobicContact CB-CB 4.04Å; H390-R478 PolarHBondContact N-O 3.14Å; H390-R478 PolarHBondContact ND1-O 3.44Å
391R75.4Confident68.9Low91 Ų9176.8 Ų76.834%0.34336%0.361SS..PPolyproline II helixtrans-63.4133.4172.9-164.6174.8179.6-171.10.5109.5R393 H414 Y415R391-R393 PolarHBondContact O-N 3.29Å; R391-H414 HydrophobicContact CG-CB 4.23Å; R391-H414 PolarHBondContact NH2-NE2 2.95Å; R391-Y415 HydrophobicContact CB-CE1 3.78Å; R391-Y415 HydrophobicContact CG-CE1 4.16Å
392K64.2Low66Low102 Ų10279.6 Ų79.644%0.44338%0.383SS..PPolyproline II helixtrans-70123.6168.8-77.8-177.5177.8172.20108.5H390 R394 E476H390-K392 PolarHBondContact O-N 3.47Å; K392-R394 PolarHBondContact O-N 3.23Å; K392-E476 WeakPolarHBondContact CE-O 3.3Å; K392-E476 PolarHBondContact NZ-O 3.3Å
393R50.9Low62.9Low235 Ų23586 Ų8689%0.88742%0.418SS*.PPolyproline II helixtrans-58.8132.9170.9-109.8-177175.2-179.8-2.3108.6R391 N395R391-R393 PolarHBondContact O-N 3.29Å; R393-N395 PolarHBondContact O-N 2.93Å
394R49.3Very low60Low111 Ų11191.1 Ų91.142%0.41945%0.452SS..PPolyproline II helixtrans-59.9117.8171.3-76.2178.2174.1-175.2-8.1107.8D30 K392 T396D30-R394 IonicContact OD1-NH1 3.74Å; D30-R394 IonicContact OD2-CZ 2.87Å; D30-R394 IonicContact OD2-NH1 2.68Å; D30-R394 PolarHBondContact OD2-NH1 3.19Å; D30-R394 IonicContact OD2-NH2 3.4Å; K392-R394 PolarHBondContact O-N 3.23Å; R394-T396 PolarHBondContact O-N 3.45Å
395N36.8Very low56.9Low105 Ų105100.2 Ų100.256%0.56149%0.494SS*.  trans-83104.5164-104.217.8000107R393 E397 K398R393-N395 PolarHBondContact O-N 2.93Å; N395-E397 PolarHBondContact O-N 2.77Å; N395-E397 VanDerWaalsContact O-N 3.14Å; N395-K398 PolarHBondContact O-N 2.79Å
396T40.9Very low53.7Low125 Ų125105.3 Ų105.377%0.76752%0.521SS*.THydrogen-bonded Turntrans-59.4-19.7178.72.50000113.1R394R394-T396 PolarHBondContact O-N 3.45Å
397E36.2Very low50.7Low174 Ų174109.7 Ų109.781%0.81355%0.552SS**THydrogen-bonded Turntrans-82.8-17.2-174.8-64.8-179.5167.700115.3N395N395-E397 PolarHBondContact O-N 2.77Å; N395-E397 VanDerWaalsContact O-N 3.14Å
398K34.9Very low47.4Very low169 Ų169114.7 Ų114.774%0.73559%0.587SS**SBendtrans-102.3-9.2-170.8-81.1-170.9175.5-1770116.1N395N395-K398 PolarHBondContact O-N 2.79Å
399Y40.5Very low44.3Very low162 Ų162119.6 Ų119.664%0.63561%0.613SS**SBendtrans-104.60.6-174.4-85.6-84.6000115Q401 A402Y399-Q401 PolarHBondContact O-N 3.42Å; Y399-A402 HydrophobicContact CD1-CB 4.28Å
400A35.1Very low41.7Very low96 Ų96122.8 Ų122.879%0.79363%0.633SS**THydrogen-bonded Turntrans-69.45.8172.500000114
401Q33.5Very low39.5Very low191 Ų191129.3 Ų129.389%0.89366%0.661SS**THydrogen-bonded Turntrans-13614.1-176-70-163.6-19.100115.3Y399Y399-Q401 PolarHBondContact O-N 3.42Å
402A32.2Very low38Very low69 Ų69130.2 Ų130.257%0.5767%0.669SS**  trans-100.3129.1176.800000111.6Y399Y399-A402 HydrophobicContact CD1-CB 4.28Å
403D30.2Very low37.5Very low154 Ų154130.4 Ų130.482%0.82467%0.672SS**  trans-61.3153.3-177.9-98.2-41.1000113.9E405D403-E405 PolarHBondContact O-N 2.95Å
404P34Very low38.4Very low108 Ų108121.6 Ų121.670%0.70164%0.64SS**G310 helixtrans-80.40.7-168-9.227.2000116.2D406P404-D406 PolarHBondContact O-N 2.94Å
405E31.3Very low40.2Very low192 Ų192117.5 Ų117.590%0.89763%0.625SS**G310 helixtrans-80.8-6.8-165-73.3-160.7155.100116.2D403D403-E405 PolarHBondContact O-N 2.95Å
406D31.7Very low42.8Very low106 Ų106114.1 Ų114.157%0.56761%0.606SS**G310 helixtrans-111.436.3-175.9-143.95.3000113.6P404 S408 N409P404-D406 PolarHBondContact O-N 2.94Å; D406-S408 PolarHBondContact O-N 3.38Å; D406-N409 PolarHBondContact O-N 2.96Å
407S32.1Very low45.2Very low92 Ų92108.4 Ų108.464%0.64357%0.572SS**THydrogen-bonded Turntrans-71.6-8-171.7630000115.2T410S407-T410 PolarHBondContact O-OG1 2.85Å
408S29.7Very low48Very low106 Ų106100.1 Ų100.174%0.74153%0.533SS*.THydrogen-bonded Turntrans-85.7-15.4178.868.40000114.4D406D406-S408 PolarHBondContact O-N 3.38Å
409N30.6Very low50.8Low104 Ų10492.1 Ų92.156%0.55650%0.498SS*.SBendtrans-105.87.4-174.5-109.5-20.8000114.8D406 K411D406-N409 PolarHBondContact O-N 2.96Å; N409-K411 PolarHBondContact O-N 2.99Å
410T37.5Very low53.5Low68 Ų6884.4 Ų84.442%0.41747%0.468SS..G310 helixtrans-75.6-16.5-170.348.70000114.7S407 H412S407-T410 PolarHBondContact O-OG1 2.85Å; T410-H412 PolarHBondContact O-N 3.32Å
411K41.5Very low56.3Low155 Ų15580.6 Ų80.667%0.67443%0.434SS*.G310 helixtrans-71.2-22.6-175.1-68.4-175178.2-179.30114.7H243 N409H243-K411 PolarHBondContact NE2-NZ 2.72Å; N409-K411 PolarHBondContact O-N 2.99Å
412H45.1Very low59.2Low111 Ų11171.6 Ų71.651%0.51439%0.391SS..G310 helixtrans-108.83.8-176-65.2-58.3000115.1T410 H414 Y449T410-H412 PolarHBondContact O-N 3.32Å; H412-H414 PolarHBondContact O-N 3.43Å; H412-Y449 HydrophobicContact CB-CD1 4.3Å; H412-Y449 HydrophobicContact CB-CD2 4.46Å; H412-Y449 HydrophobicContact CB-CG 4.12Å
413Q52.7Low62.1Low106 Ų10668.6 Ų68.650%0.49537%0.366SS..THydrogen-bonded Turntrans-68.2-5-172.6-76.2-179.2-9.500115.2
414H70.9Confident65Low49 Ų4965.5 Ų65.523%0.22735%0.345CS..THydrogen-bonded Turntrans-89.2-22.4-174.5-64.8-40.2000114.9R391 H412R391-H414 HydrophobicContact CG-CB 4.23Å; R391-H414 PolarHBondContact NH2-NE2 2.95Å; H412-H414 PolarHBondContact O-N 3.43Å
415Y87.3Confident67.6Low25 Ų2560.9 Ų60.910%0.09832%0.315CS..SBendtrans-128.8151.6-174.9-67.9-54.9000110.9E173 Q389 R391 Y449 R451E173-Y415 WeakPolarHBondContact OE1-CE2 3.4Å; E173-Y415 PolarHBondContact OE1-OH 2.81Å; E173-Y415 PolarHBondContact OE2-OH 3.23Å; Q389-Y415 HydrophobicContact CG-CD1 3.71Å; Q389-Y415 HydrophobicContact CG-CE1 4.32Å; Q389-Y415 HydrophobicContact CG-CG 4.42Å; R391-Y415 HydrophobicContact CB-CE1 3.78Å; R391-Y415 HydrophobicContact CG-CE1 4.16Å; Y415-Y449 WeakPolarHBondContact CB-O 3.31Å; Y415-Y449 WeakPolarHBondContact O-CD1 3.5Å; Y415-R451 HydrophobicContact CE1-CB 3.98Å; Y415-R451 HydrophobicContact CE1-CG 3.88Å; Y415-R451 HydrophobicContact CE2-CB 3.93Å; Y415-R451 WeakPolarHBondContact OH-CD 3.38Å
416Q90.9Very high69.9Low34 Ų3459.4 Ų59.416%0.15931%0.308CS..  trans-81.7148.4169.2-58.8-55.6-52.400108.7Q389 I418 T470 A475 A477Q389-Q416 PolarHBondContact NE2-O 3.06Å; Q389-Q416 PolarHBondContact OE1-O 2.8Å; Q416-I418 HydrophobicContact CB-CG2 4.23Å; Q416-I418 PolarHBondContact O-N 2.95Å; Q416-I418 VanDerWaalsContact O-N 3.14Å; Q416-T470 HydrophobicContact CB-CG2 3.85Å; Q416-T470 HydrophobicContact CG-CG2 4.29Å; Q416-A475 HydrophobicContact CG-CB 4.32Å; Q416-A475 VanDerWaalsContact OE1-CB 3.3Å; Q416-A477 HydrophobicContact CG-CB 4.09Å
417A91.7Very high71.9Confident6 Ų661.2 Ų61.25%0.0531%0.311CS..  trans-67.9113.916800000108.5H447 S448 Y449 T470 Y471A417-H447 HydrophobicContact CB-CB 3.88Å; A417-S448 CarbonylContact C-O 3.55Å; A417-S448 VanDerWaalsContact CA-O 3.3Å; A417-S448 WeakPolarHBondContact CA-O 3.19Å; A417-Y449 HydrophobicContact CB-CD1 3.88Å; A417-Y449 HydrophobicContact CB-CD2 4.25Å; A417-Y449 HydrophobicContact CB-CE1 3.63Å; A417-Y449 HydrophobicContact CB-CE2 4.02Å; A417-Y449 HydrophobicContact CB-CG 4.18Å; A417-T470 CarbonylContact O-C 3.49Å; A417-T470 VanDerWaalsContact O-CA 3.25Å; A417-T470 WeakPolarHBondContact O-CA 3.16Å; A417-Y471 PolarHBondContact O-N 3.49Å
418I94.9Very high73.3Confident0 Ų064.8 Ų64.80%031%0.314CS..EExtended strand (participates in β ladder)trans-116.3149.3-173.558.8168000112W352 L387 Q389 Q416 H447 S448 V453 S469 T470W352-I418 HydrophobicContact CH2-CB 4.16Å; W352-I418 HydrophobicContact CH2-CG2 3.41Å; W352-I418 VanDerWaalsContact CH2-CG2 3.41Å; W352-I418 HydrophobicContact CZ2-CG2 4.21Å; W352-I418 HydrophobicContact CZ3-CG2 3.77Å; L387-I418 HydrophobicContact CD2-CB 4.23Å; L387-I418 HydrophobicContact CD2-CD1 4.21Å; L387-I418 HydrophobicContact CG-CD1 4.13Å; Q389-I418 HydrophobicContact CB-CD1 4.16Å; Q389-I418 HydrophobicContact CG-CD1 3.94Å; Q416-I418 HydrophobicContact CB-CG2 4.23Å; Q416-I418 PolarHBondContact O-N 2.95Å; Q416-I418 VanDerWaalsContact O-N 3.14Å; I418-H447 VanDerWaalsContact O-CA 3.31Å; I418-H447 WeakPolarHBondContact O-CA 3.32Å; I418-S448 PolarHBondContact N-O 3.38Å; I418-S448 PolarHBondContact O-N 3.02Å; I418-V453 HydrophobicContact CD1-CG1 4.33Å; I418-V453 HydrophobicContact CD1-CG2 4.07Å; I418-V453 HydrophobicContact CG1-CG1 4.05Å; I418-V453 HydrophobicContact CG1-CG2 4.18Å; I418-S469 CarbonylContact C-O 3.54Å; I418-S469 WeakPolarHBondContact CA-O 3.49Å; I418-T470 HydrophobicContact CG2-CG2 4.33Å
419A93.9Very high74.8Confident1 Ų166.6 Ų66.61%0.00831%0.305CS..EExtended strand (participates in β ladder)trans-144159174.500000111.1T444 H447 P468 S469A419-T444 WeakPolarHBondContact CA-OG1 3.39Å; A419-T444 WeakPolarHBondContact CB-OG1 3.42Å; A419-H447 HydrophobicContact CB-CB 4.39Å; A419-H447 VanDerWaalsContact CB-CD2 3.44Å; A419-H447 WeakPolarHBondContact CB-CD2 3.3Å; A419-H447 WeakPolarHBondContact CB-NE2 3.31Å; A419-P468 WeakPolarHBondContact O-CA 2.94Å; A419-S469 PolarHBondContact N-O 3.16Å; A419-S469 PolarHBondContact O-N 3.08Å
420L95.7Very high76.6Confident0 Ų063.2 Ų63.20%029%0.285CS..EExtended strand (participates in β ladder)trans-125.6131.8176.1-179.768000110.2V385 L387 S443 T444 L455 L466 P468 I481V385-L420 HydrophobicContact CB-CD2 3.84Å; V385-L420 HydrophobicContact CG1-CD2 3.46Å; V385-L420 VanDerWaalsContact CG1-CD2 3.46Å; L387-L420 HydrophobicContact CD2-CB 4.37Å; L420-S443 CarbonylContact O-C 3.59Å; L420-S443 WeakPolarHBondContact O-CA 3.42Å; L420-S443 WeakPolarHBondContact O-CB 3.1Å; L420-T444 HydrophobicContact CB-CG2 3.97Å; L420-T444 PolarHBondContact N-OG1 3.04Å; L420-T444 PolarHBondContact O-N 2.66Å; L420-T444 PolarHBondContact O-OG1 3.36Å; L420-L455 HydrophobicContact CD2-CB 4.22Å; L420-L455 HydrophobicContact CD2-CD2 4.35Å; L420-L466 HydrophobicContact CD1-CB 4.32Å; L420-P468 HydrophobicContact CD1-CB 4.18Å; L420-I481 HydrophobicContact CD1-CD1 4.26Å
421H94.6Very high78.5Confident16 Ų1662 Ų627%0.07428%0.28CS..EExtended strand (participates in β ladder)trans-123.4142.8177-55.788.5000111.1R362 Y367 W423 P440 S443 L466 I467R362-H421 WeakPolarHBondContact CD-NE2 3.17Å; Y367-H421 WeakPolarHBondContact OH-CB 3.25Å; Y367-H421 PolarHBondContact OH-ND1 2.77Å; H421-W423 HydrophobicContact CB-CE3 4.24Å; H421-W423 HydrophobicContact CB-CH2 3.53Å; H421-W423 HydrophobicContact CB-CZ3 3.29Å; H421-P440 HydrophobicContact CB-CB 4.34Å; H421-S443 VanDerWaalsContact CD2-CB 3.49Å; H421-S443 WeakPolarHBondContact CD2-CB 3.24Å; H421-L466 WeakPolarHBondContact O-CA 3.5Å; H421-I467 PolarHBondContact N-O 2.75Å; H421-I467 VanDerWaalsContact N-O 3.08Å; H421-I467 PolarHBondContact O-N 3.4Å
422M94.9Very high80.2Confident1 Ų155.8 Ų55.81%0.00525%0.254CS..EExtended strand (participates in β ladder)trans-128.7135.7-175.6-175.6-170.6-67.600111L375 V385 P440 C441 A442 L455 L459 Y464 L465 L466L375-M422 HydrophobicContact CD2-CE 4.44Å; V385-M422 HydrophobicContact CG2-CE 3.83Å; M422-P440 CarbonylContact O-C 3.49Å; M422-P440 WeakPolarHBondContact O-CA 3.39Å; M422-P440 VanDerWaalsContact O-CB 3.24Å; M422-P440 WeakPolarHBondContact O-CB 3.39Å; M422-C441 PolarHBondContact O-N 3.05Å; M422-C441 PolarHBondContact O-SG 3.25Å; M422-A442 WeakPolarHBondContact CA-O 3.46Å; M422-A442 HydrophobicContact CB-CB 4.24Å; M422-A442 WeakPolarHBondContact CB-O 3.25Å; M422-A442 PolarHBondContact N-O 3.49Å; M422-A442 PolarHBondContact O-N 3.12Å; M422-A442 HydrophobicContact SD-CB 4.28Å; M422-L455 HydrophobicContact CB-CD2 4.12Å; M422-L455 HydrophobicContact CE-CD2 3.69Å; M422-L459 HydrophobicContact CE-CD1 4.13Å; M422-L459 HydrophobicContact SD-CD1 3.83Å; M422-L459 HydrophobicContact SD-CD2 4.04Å; M422-Y464 HydrophobicContact CG-CD1 3.99Å; M422-Y464 HydrophobicContact SD-CD1 3.81Å; M422-Y464 HydrophobicContact SD-CE1 4.47Å; M422-Y464 HydrophobicContact SD-CG 4.38Å; M422-L465 CarbonylContact C-O 3.51Å; M422-L465 VanDerWaalsContact CA-O 3.29Å; M422-L465 WeakPolarHBondContact CA-O 3.26Å; M422-L466 HydrophobicContact CB-CD2 3.92Å; M422-L466 HydrophobicContact CE-CD2 3.49Å; M422-L466 VanDerWaalsContact CE-CD2 3.49Å; M422-L466 HydrophobicContact CG-CD2 3.71Å; M422-L466 HydrophobicContact SD-CD2 4.36Å
423W92.3Very high81.7Confident7 Ų754.2 Ų54.23%0.02726%0.255CS..EExtended strand (participates in β ladder)trans-126.8137.5172.3-71.4-103.2000111Y367 H421 M435 L436 K438 P439 P440 Y464 L465 I467Y367-W423 AromaticContact CE1-CH2 3.91Å; Y367-W423 HydrophobicContact CE1-CH2 3.91Å; Y367-W423 WeakPolarHBondContact OH-CH2 3.39Å; H421-W423 HydrophobicContact CB-CE3 4.24Å; H421-W423 HydrophobicContact CB-CH2 3.53Å; H421-W423 HydrophobicContact CB-CZ3 3.29Å; W423-M435 HydrophobicContact CB-CG 4.2Å; W423-M435 HydrophobicContact CB-SD 4.06Å; W423-M435 HydrophobicContact CG-CG 4.12Å; W423-M435 PolarHBondContact NE1-O 3.36Å; W423-L436 HydrophobicContact CH2-CD2 3.96Å; W423-L436 HydrophobicContact CZ2-CD2 3.92Å; W423-L436 HydrophobicContact CZ3-CD2 4.26Å; W423-K438 PolarHBondContact NE1-O 2.81Å; W423-P439 PolarHBondContact NE1-O 3.33Å; W423-P440 HydrophobicContact CD2-CB 4.14Å; W423-P440 HydrophobicContact CE3-CB 4.46Å; W423-P440 HydrophobicContact CH2-CB 4.41Å; W423-P440 HydrophobicContact CZ2-CB 4.15Å; W423-Y464 CarbonylContact O-C 3.53Å; W423-Y464 WeakPolarHBondContact O-CA 3.44Å; W423-L465 PolarHBondContact N-O 3.29Å; W423-L465 PolarHBondContact O-N 2.79Å; W423-I467 HydrophobicContact CE3-CD1 4.5Å; W423-I467 HydrophobicContact CH2-CD1 4.44Å; W423-I467 HydrophobicContact CZ3-CB 4.16Å; W423-I467 HydrophobicContact CZ3-CD1 3.92Å; W423-I467 HydrophobicContact CZ3-CG1 4.01Å
424K92.6Very high82.8Confident88 Ų8858 Ų5838%0.38327%0.265SS..EExtended strand (participates in β ladder)trans-77.8132167.9-169.1173.4-173.7173.60110C441 Y464K424-C441 PolarHBondContact N-SG 2.93Å; K424-C441 VanDerWaalsContact N-SG 3.38Å; K424-Y464 HydrophobicContact CB-CD1 4.05Å; K424-Y464 HydrophobicContact CB-CE1 3.74Å; K424-Y464 HydrophobicContact CD-CE1 4.17Å; K424-Y464 HydrophobicContact CG-CD1 4.37Å; K424-Y464 HydrophobicContact CG-CE1 3.84Å
425V87.8Confident83.3Confident12 Ų1256.4 Ų56.47%0.07326%0.258CS..EExtended strand (participates in β ladder)trans-107.7103.5-178.8-175.50000109.7W374 F430 M435 Y463 L465 L651W374-V425 HydrophobicContact CH2-CB 4.08Å; W374-V425 HydrophobicContact CH2-CG1 4.01Å; W374-V425 HydrophobicContact CH2-CG2 3.68Å; W374-V425 HydrophobicContact CZ3-CB 3.94Å; W374-V425 HydrophobicContact CZ3-CG1 4.36Å; W374-V425 HydrophobicContact CZ3-CG2 3.51Å; V425-F430 HydrophobicContact CG1-CD1 3.42Å; V425-F430 VanDerWaalsContact CG1-CD1 3.42Å; V425-F430 HydrophobicContact CG1-CE1 3.71Å; V425-F430 HydrophobicContact CG1-CG 4.05Å; V425-M435 HydrophobicContact CG2-CE 4.47Å; V425-M435 HydrophobicContact CG2-SD 3.65Å; V425-Y463 PolarHBondContact N-O 2.99Å; V425-L465 HydrophobicContact CG2-CB 4.23Å; V425-L651 HydrophobicContact CB-CD1 4.42Å; V425-L651 HydrophobicContact CG1-CD1 3.94Å
426E79.3Confident83.1Confident160 Ų16056.1 Ų56.175%0.74826%0.258SS*.  trans-80.2-29.6-174.4-62.3174.916900113.3
427K73.8Confident82.6Confident145 Ų14561.2 Ų61.263%0.6329%0.286SS*.SBendtrans-112.1136.8-171.8-63.1-173.5-178.1-175.70110.6R429K427-R429 VanDerWaalsContact CB-O 3.26Å; K427-R429 WeakPolarHBondContact CB-O 3.47Å; K427-R429 PolarHBondContact O-N 3.34Å; K427-R429 VanDerWaalsContact O-N 3.1Å
428K61.7Low82.2Confident167 Ų16766.9 Ų66.973%0.72631%0.31SS*.SBendtrans-56.4-27173.2-78-175177.61790113.2K650 L651K428-K650 VanDerWaalsContact O-CA 3.31Å; K428-K650 WeakPolarHBondContact O-CA 3.47Å; K428-L651 HydrophobicContact CG-CB 4.49Å; K428-L651 HydrophobicContact CG-CD2 4.24Å; K428-L651 PolarHBondContact O-N 3.34Å
429R60.7Low81.7Confident143 Ų14371.9 Ų71.954%0.5434%0.342SS..EExtended strand (participates in β ladder)trans-122127.6171.4-61.2-174.7-163.2-172.15.9109.4K427 E649 K650K427-R429 VanDerWaalsContact CB-O 3.26Å; K427-R429 WeakPolarHBondContact CB-O 3.47Å; K427-R429 PolarHBondContact O-N 3.34Å; K427-R429 VanDerWaalsContact O-N 3.1Å; R429-E649 VanDerWaalsContact CA-O 3.31Å; R429-E649 WeakPolarHBondContact CA-O 3.33Å; R429-K650 HydrophobicContact CG-CG 3.91Å
430F69.6Low81.5Confident33 Ų3373.3 Ų73.315%0.14535%0.351CS..EExtended strand (participates in β ladder)trans-142.4163.7177.766.8-84.6000110.1W374 V425 L432 M435 E649W374-F430 AromaticContact CH2-CE1 3.49Å; W374-F430 HydrophobicContact CH2-CE1 3.49Å; W374-F430 VanDerWaalsContact CH2-CE1 3.49Å; W374-F430 AromaticContact CH2-CZ 3.62Å; W374-F430 HydrophobicContact CH2-CZ 3.62Å; W374-F430 AromaticContact CZ2-CE1 3.67Å; W374-F430 HydrophobicContact CZ2-CE1 3.67Å; W374-F430 AromaticContact CZ2-CZ 3.68Å; W374-F430 HydrophobicContact CZ2-CZ 3.68Å; V425-F430 HydrophobicContact CG1-CD1 3.42Å; V425-F430 VanDerWaalsContact CG1-CD1 3.42Å; V425-F430 HydrophobicContact CG1-CE1 3.71Å; V425-F430 HydrophobicContact CG1-CG 4.05Å; F430-L432 HydrophobicContact CE2-CB 4.46Å; F430-L432 HydrophobicContact CE2-CD1 4.49Å; F430-M435 HydrophobicContact CD2-CB 4.41Å; F430-M435 HydrophobicContact CD2-CE 3.45Å; F430-M435 VanDerWaalsContact CD2-CE 3.45Å; F430-M435 HydrophobicContact CD2-SD 4.01Å; F430-M435 HydrophobicContact CE2-CE 3.09Å; F430-M435 HydrophobicContact CE2-SD 4.14Å; F430-M435 HydrophobicContact CZ-CE 3.92Å; F430-E649 VanDerWaalsContact CE2-OE2 3.26Å; F430-E649 WeakPolarHBondContact CE2-OE2 3.37Å; F430-E649 HydrophobicContact CZ-CB 4.45Å; F430-E649 WeakPolarHBondContact CZ-OE2 3.26Å
431S77.2Confident81.3Confident44 Ų4476.8 Ų76.831%0.30838%0.375SS..  trans-99.9120.6171.1158.50000107.4S433 R434 M435S431-S433 PolarHBondContact O-N 2.93Å; S431-S433 PolarHBondContact OG-OG 2.86Å; S431-S433 VanDerWaalsContact OG-OG 3.07Å; S431-R434 PolarHBondContact O-N 3.38Å; S431-R434 PolarHBondContact OG-N 3.11Å; S431-M435 PolarHBondContact O-N 3.08Å
432L77.6Confident81.1Confident23 Ų2376.5 Ų76.512%0.1238%0.375CS..Hα-helixtrans-55.9-50.9179.2179.366.5000110.9K372 F430 R434 M435 L436 L465K372-L432 HydrophobicContact CD-CD1 4.34Å; K372-L432 HydrophobicContact CD-CD2 4.26Å; K372-L432 VanDerWaalsContact CE-CD2 3.44Å; F430-L432 HydrophobicContact CE2-CB 4.46Å; F430-L432 HydrophobicContact CE2-CD1 4.49Å; L432-R434 VanDerWaalsContact C-N 3.34Å; L432-R434 PolarHBondContact O-N 2.6Å; L432-M435 HydrophobicContact CD1-CE 3.83Å; L432-M435 WeakPolarHBondContact O-CB 3.47Å; L432-M435 PolarHBondContact O-N 3.4Å; L432-L436 HydrophobicContact CD1-CD1 4.02Å; L432-L436 HydrophobicContact CD1-CD2 4.12Å; L432-L436 HydrophobicContact CD1-CG 3.96Å; L432-L436 HydrophobicContact CD2-CD1 4.45Å; L432-L436 HydrophobicContact CG-CD1 3.92Å; L432-L436 HydrophobicContact CG-CG 4.16Å; L432-L436 WeakPolarHBondContact O-CG 3.35Å; L432-L436 PolarHBondContact O-N 3.34Å; L432-L465 HydrophobicContact CD1-CD2 3.82Å
433S74.7Confident80.8Confident78 Ų7878.7 Ų78.755%0.54539%0.391SS..Hα-helixtrans-55.7-46.217952.70000112.7S431 M435 L436 N437S431-S433 PolarHBondContact O-N 2.93Å; S431-S433 PolarHBondContact OG-OG 2.86Å; S431-S433 VanDerWaalsContact OG-OG 3.07Å; S433-M435 VanDerWaalsContact C-N 3.3Å; S433-M435 PolarHBondContact O-N 2.87Å; S433-L436 PolarHBondContact O-N 2.8Å; S433-N437 PolarHBondContact O-N 2.98Å; S433-N437 VanDerWaalsContact O-N 3.12Å; S433-N437 PolarHBondContact O-OD1 3.4Å
434R75.9Confident80.6Confident185 Ų18578.9 Ų78.970%0.69839%0.393SS*.Hα-helixtrans-63.6-35.3177.2-171.6-179.5-66.3172.2-2112.7S431 L432S431-R434 PolarHBondContact O-N 3.38Å; S431-R434 PolarHBondContact OG-N 3.11Å; L432-R434 VanDerWaalsContact C-N 3.34Å; L432-R434 PolarHBondContact O-N 2.6Å
435M82.4Confident79.8Confident17 Ų1780.4 Ų80.48%0.08440%0.401CS..Hα-helixtrans-72.8-42.4178178.8173.855.700111.9W423 V425 F430 S431 L432 S433 N437 K438 L465W423-M435 HydrophobicContact CB-CG 4.2Å; W423-M435 HydrophobicContact CB-SD 4.06Å; W423-M435 HydrophobicContact CG-CG 4.12Å; W423-M435 PolarHBondContact NE1-O 3.36Å; V425-M435 HydrophobicContact CG2-CE 4.47Å; V425-M435 HydrophobicContact CG2-SD 3.65Å; F430-M435 HydrophobicContact CD2-CB 4.41Å; F430-M435 HydrophobicContact CD2-CE 3.45Å; F430-M435 VanDerWaalsContact CD2-CE 3.45Å; F430-M435 HydrophobicContact CD2-SD 4.01Å; F430-M435 HydrophobicContact CE2-CE 3.09Å; F430-M435 HydrophobicContact CE2-SD 4.14Å; F430-M435 HydrophobicContact CZ-CE 3.92Å; S431-M435 PolarHBondContact O-N 3.08Å; L432-M435 HydrophobicContact CD1-CE 3.83Å; L432-M435 WeakPolarHBondContact O-CB 3.47Å; L432-M435 PolarHBondContact O-N 3.4Å; S433-M435 VanDerWaalsContact C-N 3.3Å; S433-M435 PolarHBondContact O-N 2.87Å; M435-N437 PolarHBondContact O-N 2.98Å; M435-K438 WeakPolarHBondContact O-CB 3.36Å; M435-K438 PolarHBondContact O-N 2.93Å; M435-L465 HydrophobicContact CE-CB 4.48Å; M435-L465 HydrophobicContact CE-CD2 3.38Å
436L83.6Confident79.5Confident18 Ų1882.8 Ų82.89%0.09442%0.417CS..Hα-helixtrans-65.5-27.5178.4-62-175.7000112.4R362 Y367 W423 L432 S433 K438 I467R362-L436 PolarHBondContact NH2-O 3.23Å; R362-L436 VanDerWaalsContact NH2-O 3.14Å; Y367-L436 HydrophobicContact CD1-CD1 4.27Å; Y367-L436 HydrophobicContact CE1-CD2 4.32Å; W423-L436 HydrophobicContact CH2-CD2 3.96Å; W423-L436 HydrophobicContact CZ2-CD2 3.92Å; W423-L436 HydrophobicContact CZ3-CD2 4.26Å; L432-L436 HydrophobicContact CD1-CD1 4.02Å; L432-L436 HydrophobicContact CD1-CD2 4.12Å; L432-L436 HydrophobicContact CD1-CG 3.96Å; L432-L436 HydrophobicContact CD2-CD1 4.45Å; L432-L436 HydrophobicContact CG-CD1 3.92Å; L432-L436 HydrophobicContact CG-CG 4.16Å; L432-L436 WeakPolarHBondContact O-CG 3.35Å; L432-L436 PolarHBondContact O-N 3.34Å; S433-L436 PolarHBondContact O-N 2.8Å; L436-K438 PolarHBondContact O-N 3.28Å; L436-I467 HydrophobicContact CD2-CD1 3.46Å; L436-I467 VanDerWaalsContact CD2-CD1 3.46Å
437N80.6Confident79.9Confident141 Ų14176.8 Ų76.875%0.75439%0.39SS*.THydrogen-bonded Turntrans-68.7-17.1171.6-69.3-6.4000113.3S433 M435S433-N437 PolarHBondContact O-N 2.98Å; S433-N437 VanDerWaalsContact O-N 3.12Å; S433-N437 PolarHBondContact O-OD1 3.4Å; M435-N437 PolarHBondContact O-N 2.98Å
438K82.6Confident80.5Confident125 Ų12570.9 Ų70.954%0.54337%0.366SS..SBendtrans-82.1150.3171.1-63.4-173.8176.4-170.20110.2R362 W423 M435 L436R362-K438 PolarHBondContact NH2-O 3.06Å; R362-K438 VanDerWaalsContact NH2-O 3.12Å; W423-K438 PolarHBondContact NE1-O 2.81Å; M435-K438 WeakPolarHBondContact O-CB 3.36Å; M435-K438 PolarHBondContact O-N 2.93Å; L436-K438 PolarHBondContact O-N 3.28Å
439P84.1Confident81.7Confident105 Ų10568 Ų6868%0.68235%0.351SS*.PPolyproline II helixtrans-58147169.325.6-33.7000110.1W423W423-P439 PolarHBondContact NE1-O 3.33Å
440P89.8Confident83Confident31 Ų3163.8 Ų63.820%0.20134%0.338CS..PPolyproline II helixtrans-67.7148.9176.132-24.8000108.7R362 H421 M422 W423 A442R362-P440 VanDerWaalsContact NH1-CG 3.35Å; H421-P440 HydrophobicContact CB-CB 4.34Å; M422-P440 CarbonylContact O-C 3.49Å; M422-P440 WeakPolarHBondContact O-CA 3.39Å; M422-P440 VanDerWaalsContact O-CB 3.24Å; M422-P440 WeakPolarHBondContact O-CB 3.39Å; W423-P440 HydrophobicContact CD2-CB 4.14Å; W423-P440 HydrophobicContact CE3-CB 4.46Å; W423-P440 HydrophobicContact CH2-CB 4.41Å; W423-P440 HydrophobicContact CZ2-CB 4.15Å; P440-A442 PolarHBondContact O-N 3.44Å
441C91.1Very high84.1Confident74 Ų7463.3 Ų63.350%0.534%0.335SS..SBendtrans-72.2-22.4173.364.80000111.9M422 K424M422-C441 PolarHBondContact O-N 3.05Å; M422-C441 PolarHBondContact O-SG 3.25Å; K424-C441 PolarHBondContact N-SG 2.93Å; K424-C441 VanDerWaalsContact N-SG 3.38Å
442A90Very high84.8Confident9 Ų961.9 Ų61.97%0.07432%0.324CS..EExtended strand (participates in β ladder)trans-155.8145.6172.500000109.8M422 P440 L455 R457M422-A442 WeakPolarHBondContact CA-O 3.46Å; M422-A442 HydrophobicContact CB-CB 4.24Å; M422-A442 WeakPolarHBondContact CB-O 3.25Å; M422-A442 PolarHBondContact N-O 3.49Å; M422-A442 PolarHBondContact O-N 3.12Å; M422-A442 HydrophobicContact SD-CB 4.28Å; P440-A442 PolarHBondContact O-N 3.44Å; A442-L455 HydrophobicContact CB-CD1 4.08Å; A442-L455 HydrophobicContact CB-CD2 3.94Å; A442-L455 HydrophobicContact CB-CG 4.39Å; A442-R457 HydrophobicContact CB-CG 3.88Å
443S90.1Very high85.6Confident47 Ų4761.3 Ų61.333%0.32932%0.321SS..EExtended strand (participates in β ladder)trans-152.6160.517454.40000110.8L420 H421 L455L420-S443 CarbonylContact O-C 3.59Å; L420-S443 WeakPolarHBondContact O-CA 3.42Å; L420-S443 WeakPolarHBondContact O-CB 3.1Å; H421-S443 VanDerWaalsContact CD2-CB 3.49Å; H421-S443 WeakPolarHBondContact CD2-CB 3.24Å; S443-L455 WeakPolarHBondContact O-CD1 3.29Å
444T87.5Confident86.5Confident12 Ų1258.8 Ų58.87%0.07430%0.303CS..  trans-63.1152.716354.90000109.4A419 L420 C446 V453A419-T444 WeakPolarHBondContact CA-OG1 3.39Å; A419-T444 WeakPolarHBondContact CB-OG1 3.42Å; L420-T444 HydrophobicContact CB-CG2 3.97Å; L420-T444 PolarHBondContact N-OG1 3.04Å; L420-T444 PolarHBondContact O-N 2.66Å; L420-T444 PolarHBondContact O-OG1 3.36Å; T444-C446 PolarHBondContact O-N 3.07Å; T444-V453 HydrophobicContact CG2-CB 3.95Å; T444-V453 HydrophobicContact CG2-CG2 3.9Å
445H76.6Confident87.2Confident119 Ų11950.4 Ų50.455%0.55127%0.271SS*.SBendtrans-62.2-43.4-172.2-65.7-70.1000113.6
446C81.2Confident87.6Confident62 Ų6250.4 Ų50.442%0.41927%0.273SS..SBendtrans-152.1174.6176.761.20000109.4T444 S448T444-C446 PolarHBondContact O-N 3.07Å; C446-S448 PolarHBondContact O-N 2.66Å
447H88Confident87.9Confident35 Ų3555.7 Ų55.716%0.16229%0.292CS..  trans-72.3116.9164.5-67.677.3000109.2S361 A417 I418 A419 S469 T470 Y471S361-H447 VanDerWaalsContact CB-CE1 3.49Å; S361-H447 WeakPolarHBondContact CB-CE1 3.42Å; A417-H447 HydrophobicContact CB-CB 3.88Å; I418-H447 VanDerWaalsContact O-CA 3.31Å; I418-H447 WeakPolarHBondContact O-CA 3.32Å; A419-H447 HydrophobicContact CB-CB 4.39Å; A419-H447 VanDerWaalsContact CB-CD2 3.44Å; A419-H447 WeakPolarHBondContact CB-CD2 3.3Å; A419-H447 WeakPolarHBondContact CB-NE2 3.31Å; H447-S469 PolarHBondContact NE2-OG 2.86Å; H447-S469 VanDerWaalsContact NE2-OG 3.12Å; H447-T470 PolarHBondContact NE2-O 3.21Å; H447-Y471 HydrophobicContact CB-CD2 4.02Å; H447-Y471 HydrophobicContact CB-CG 4.32Å; H447-Y471 VanDerWaalsContact CD2-CA 3.44Å; H447-Y471 WeakPolarHBondContact CD2-CA 3.4Å; H447-Y471 PolarHBondContact CD2-N 3.2Å; H447-Y471 AromaticContact CG-CD2 3.87Å; H447-Y471 AromaticContact ND1-CD2 3.81Å
448S85.6Confident88.5Confident20 Ų2053.9 Ų53.914%0.1429%0.288CS..BIsolated β-bridgetrans-110.8144.7-179.1-174.10000110.9A417 I418 C446 E450A417-S448 CarbonylContact C-O 3.55Å; A417-S448 VanDerWaalsContact CA-O 3.3Å; A417-S448 WeakPolarHBondContact CA-O 3.19Å; I418-S448 PolarHBondContact N-O 3.38Å; I418-S448 PolarHBondContact O-N 3.02Å; C446-S448 PolarHBondContact O-N 2.66Å; S448-E450 PolarHBondContact O-N 3.11Å; S448-E450 VanDerWaalsContact O-N 3.13Å; S448-E450 WeakPolarHBondContact OG-CG 3.09Å; S448-E450 PolarHBondContact OG-N 2.87Å; S448-E450 PolarHBondContact OG-OE1 2.81Å
449Y88.1Confident89.1Confident106 Ų10648.4 Ų48.442%0.41626%0.264SS..  trans-78.121.7173.5-68.1-78000112.9H412 Y415 A417H412-Y449 HydrophobicContact CB-CD1 4.3Å; H412-Y449 HydrophobicContact CB-CD2 4.46Å; H412-Y449 HydrophobicContact CB-CG 4.12Å; Y415-Y449 WeakPolarHBondContact CB-O 3.31Å; Y415-Y449 WeakPolarHBondContact O-CD1 3.5Å; A417-Y449 HydrophobicContact CB-CD1 3.88Å; A417-Y449 HydrophobicContact CB-CD2 4.25Å; A417-Y449 HydrophobicContact CB-CE1 3.63Å; A417-Y449 HydrophobicContact CB-CE2 4.02Å; A417-Y449 HydrophobicContact CB-CG 4.18Å
450E87.3Confident89.6Confident56 Ų5648.2 Ų48.226%0.26225%0.254SS..SBendtrans-79149.5176.6-76.1167.7-122.500111.5Q389 S448 E452Q389-E450 PolarHBondContact NE2-O 3.36Å; S448-E450 PolarHBondContact O-N 3.11Å; S448-E450 VanDerWaalsContact O-N 3.13Å; S448-E450 WeakPolarHBondContact OG-CG 3.09Å; S448-E450 PolarHBondContact OG-N 2.87Å; S448-E450 PolarHBondContact OG-OE1 2.81Å; E450-E452 PolarHBondContact O-N 3.3Å
451R91.6Very high89.8Confident23 Ų2349.6 Ų49.69%0.08726%0.263CS..SBendtrans-58.6-33.3172.3-174.9-176.6171.5-165.1-8.6111.8E173 D177 L388 Q389 Y415E173-R451 HydrophobicContact CG-CB 4.16Å; D177-R451 VanDerWaalsContact CG-NH1 3.31Å; D177-R451 IonicContact OD1-CZ 3.25Å; D177-R451 VanDerWaalsContact OD1-CZ 3.23Å; D177-R451 IonicContact OD1-NH1 3.97Å; D177-R451 PolarHBondContact OD1-NH1 2.68Å; D177-R451 IonicContact OD1-NH2 3.55Å; D177-R451 PolarHBondContact OD1-NH2 3.02Å; D177-R451 IonicContact OD2-NH1 2.73Å; D177-R451 PolarHBondContact OD2-NH1 2.79Å; D177-R451 IonicContact OD2-NH2 2.71Å; L388-R451 CarbonylContact C-O 3.5Å; L388-R451 WeakPolarHBondContact CA-O 3.38Å; Q389-R451 WeakPolarHBondContact CG-O 3.49Å; Q389-R451 PolarHBondContact N-O 2.85Å; Y415-R451 HydrophobicContact CE1-CB 3.98Å; Y415-R451 HydrophobicContact CE1-CG 3.88Å; Y415-R451 HydrophobicContact CE2-CB 3.93Å; Y415-R451 WeakPolarHBondContact OH-CD 3.38Å
452E93.4Very high89.7Confident14 Ų1447 Ų477%0.06525%0.249CC..EExtended strand (participates in β ladder)trans-140.2135.6-177.5174.4158.7-111.300111.3S386 L387 L388 E450 V454 R482S386-E452 WeakPolarHBondContact CB-OE1 3.08Å; S386-E452 PolarHBondContact OG-OE1 2.79Å; L387-E452 VanDerWaalsContact O-CA 3.31Å; L387-E452 WeakPolarHBondContact O-CA 3.22Å; L388-E452 HydrophobicContact CB-CB 4.37Å; L388-E452 HydrophobicContact CB-CG 4.44Å; L388-E452 HydrophobicContact CD1-CB 4.42Å; L388-E452 HydrophobicContact CG-CB 4.43Å; E450-E452 PolarHBondContact O-N 3.3Å; E452-V454 HydrophobicContact CG-CG2 4.16Å; E452-R482 IonicContact OE1-CZ 2.65Å; E452-R482 IonicContact OE1-NE 2.77Å; E452-R482 PolarHBondContact OE1-NE 2.86Å; E452-R482 IonicContact OE1-NH2 3.59Å; E452-R482 PolarHBondContact OE1-NH2 3.16Å; E452-R482 IonicContact OE2-NH2 3.87Å; E452-R482 PolarHBondContact OE2-NH2 3.26Å
453V93.3Very high89.8Confident11 Ų1149.6 Ų49.67%0.06726%0.258CS..EExtended strand (participates in β ladder)trans-118.7142.5169.7-62.80000110.1S386 L387 I418 T444S386-V453 WeakPolarHBondContact CA-O 3.43Å; L387-V453 HydrophobicContact CB-CG2 3.83Å; L387-V453 HydrophobicContact CD2-CG2 4.09Å; L387-V453 HydrophobicContact CG-CG2 4.34Å; L387-V453 PolarHBondContact N-O 3.34Å; L387-V453 PolarHBondContact O-N 3.07Å; I418-V453 HydrophobicContact CD1-CG1 4.33Å; I418-V453 HydrophobicContact CD1-CG2 4.07Å; I418-V453 HydrophobicContact CG1-CG1 4.05Å; I418-V453 HydrophobicContact CG1-CG2 4.18Å; T444-V453 HydrophobicContact CG2-CB 3.95Å; T444-V453 HydrophobicContact CG2-CG2 3.9Å
454V93.4Very high90Very high25 Ų2547.7 Ų47.715%0.15224%0.243CC..EExtended strand (participates in β ladder)trans-122.7141.2-171.7-171.50000110.9V182 E184 L384 E452V182-V454 HydrophobicContact CG1-CB 4.46Å; V182-V454 HydrophobicContact CG1-CG1 4.13Å; V182-V454 HydrophobicContact CG1-CG2 3.45Å; V182-V454 VanDerWaalsContact CG1-CG2 3.45Å; E184-V454 HydrophobicContact CG-CB 3.82Å; E184-V454 HydrophobicContact CG-CG1 4.34Å; E184-V454 HydrophobicContact CG-CG2 3.7Å; E184-V454 WeakPolarHBondContact OE1-CB 3.11Å; E184-V454 WeakPolarHBondContact OE1-CG1 3.23Å; L384-V454 HydrophobicContact CD1-CG1 3.91Å; L384-V454 HydrophobicContact CD2-CG1 3.79Å; L384-V454 HydrophobicContact CG-CG1 3.67Å; E452-V454 HydrophobicContact CG-CG2 4.16Å
455L91.8Very high90.2Very high8 Ų847.2 Ų47.24%0.04224%0.24CC..EExtended strand (participates in β ladder)trans-129.4110.6174.8-179.666.8000109.1L384 V385 L420 M422 A442 S443L384-L455 CarbonylContact C-O 3.48Å; L384-L455 WeakPolarHBondContact CA-O 3.44Å; V385-L455 PolarHBondContact N-O 3.22Å; V385-L455 PolarHBondContact O-N 3.07Å; L420-L455 HydrophobicContact CD2-CB 4.22Å; L420-L455 HydrophobicContact CD2-CD2 4.35Å; M422-L455 HydrophobicContact CB-CD2 4.12Å; M422-L455 HydrophobicContact CE-CD2 3.69Å; A442-L455 HydrophobicContact CB-CD1 4.08Å; A442-L455 HydrophobicContact CB-CD2 3.94Å; A442-L455 HydrophobicContact CB-CG 4.39Å; S443-L455 WeakPolarHBondContact O-CD1 3.29Å
456C90.6Very high91.2Very high18 Ų1841.5 Ų41.512%0.12221%0.214CC..EExtended strand (participates in β ladder)trans-111.6128.3174.7-1700000111.2Y337 E382 V383 L384Y337-C456 HydrophobicContact CD2-CB 4.04Å; Y337-C456 HydrophobicContact CE2-CB 3.65Å; E382-C456 PolarHBondContact OE1-SG 3.28Å; V383-C456 WeakPolarHBondContact O-CA 3.37Å; L384-C456 HydrophobicContact CB-CB 4.44Å; L384-C456 HydrophobicContact CD1-CB 4.47Å; L384-C456 HydrophobicContact CG-CB 4.42Å
457R90.4Very high91.8Very high128 Ų12838.6 Ų38.648%0.48319%0.194SC..EExtended strand (participates in β ladder)trans-148.5145.2175.7-71.5-64.6162.4168-3.9112.6V383 A442 L459V383-R457 PolarHBondContact N-O 3.12Å; V383-R457 PolarHBondContact O-N 3.09Å; A442-R457 HydrophobicContact CB-CG 3.88Å; R457-L459 HydrophobicContact CB-CD2 3.9Å; R457-L459 HydrophobicContact CB-CG 4.42Å; R457-L459 PolarHBondContact O-N 3.21Å
458P92.6Very high92.3Very high103 Ų10336.9 Ų36.967%0.66919%0.186SC*.EExtended strand (participates in β ladder)trans-67.9125.6158.830-31.8000108.7G381G381-P458 WeakPolarHBondContact O-CA 3.39Å
459L93.9Very high92.7Very high10 Ų1036 Ų365%0.05218%0.179CC..EExtended strand (participates in β ladder)trans-118.9137.5-179.9-62.1-173.2000110.3L375 V377 T380 G381 V383 M422 R457 Y464L375-L459 HydrophobicContact CD2-CD1 4.19Å; V377-L459 HydrophobicContact CG1-CB 4.43Å; V377-L459 HydrophobicContact CG2-CB 4.16Å; V377-L459 HydrophobicContact CG2-CD1 4.02Å; T380-L459 VanDerWaalsContact CA-O 3.32Å; T380-L459 WeakPolarHBondContact CA-O 3.48Å; G381-L459 PolarHBondContact N-O 3.4Å; G381-L459 VanDerWaalsContact N-O 3.12Å; G381-L459 PolarHBondContact O-N 2.87Å; V383-L459 HydrophobicContact CB-CD1 3.83Å; V383-L459 HydrophobicContact CB-CG 4.13Å; V383-L459 HydrophobicContact CG1-CD1 4.25Å; V383-L459 HydrophobicContact CG2-CB 4.1Å; V383-L459 HydrophobicContact CG2-CD1 3.86Å; V383-L459 HydrophobicContact CG2-CG 4.07Å; M422-L459 HydrophobicContact CE-CD1 4.13Å; M422-L459 HydrophobicContact SD-CD1 3.83Å; M422-L459 HydrophobicContact SD-CD2 4.04Å; R457-L459 HydrophobicContact CB-CD2 3.9Å; R457-L459 HydrophobicContact CB-CG 4.42Å; R457-L459 PolarHBondContact O-N 3.21Å; L459-Y464 HydrophobicContact CB-CE2 4.21Å; L459-Y464 HydrophobicContact CD1-CD1 4.26Å; L459-Y464 HydrophobicContact CD1-CD2 4.27Å; L459-Y464 HydrophobicContact CD1-CE1 4.19Å; L459-Y464 HydrophobicContact CD1-CE2 4.22Å; L459-Y464 HydrophobicContact CD1-CG 4.3Å; L459-Y464 HydrophobicContact CD2-CD1 4.46Å; L459-Y464 HydrophobicContact CD2-CE1 3.83Å; L459-Y464 HydrophobicContact CG-CE1 4.43Å
460E95.4Very high93Very high101 Ų10130.9 Ų30.947%0.47216%0.16SC..  trans-75.7160169.8-66.3-56.4147.500111.5T380 G462 Y464T380-E460 WeakPolarHBondContact CG2-OE1 3.36Å; T380-E460 PolarHBondContact OG1-OE2 3.42Å; E460-G462 PolarHBondContact O-N 2.77Å; E460-Y464 PolarHBondContact N-OH 2.57Å; E460-Y464 WeakPolarHBondContact O-CE2 3.42Å; E460-Y464 PolarHBondContact O-OH 2.84Å
461P94Very high93Very high61 Ų6134.1 Ų34.140%0.39617%0.17SC..SBendtrans-53.2135.1173.4-26.333.8000111.9V377 C378 T380V377-P461 WeakPolarHBondContact O-CA 3.41Å; C378-P461 WeakPolarHBondContact O-CB 3.3Å; T380-P461 VanDerWaalsContact OG1-CD 3.29Å; T380-P461 WeakPolarHBondContact OG1-CD 3.48Å
462G89.3Confident92.8Very high20 Ų2038.8 Ų38.821%0.20619%0.193CC..EExtended strand (participates in β ladder)trans154.4-163.9179.800000114R376 V377 E460R376-G462 WeakPolarHBondContact CA-O 3.29Å; V377-G462 PolarHBondContact N-O 3.37Å; V377-G462 PolarHBondContact O-N 3.49Å; E460-G462 PolarHBondContact O-N 2.77Å
463Y91.5Very high92.3Very high63 Ų6341.5 Ų41.525%0.24721%0.212CC..EExtended strand (participates in β ladder)trans-117.6134.9-179.9-69.6-101000109.6R376 V425 L651R376-Y463 HydrophobicContact CB-CD1 4.14Å; R376-Y463 HydrophobicContact CB-CE1 4.02Å; R376-Y463 HydrophobicContact CG-CD1 4.25Å; R376-Y463 HydrophobicContact CG-CE1 3.86Å; R376-Y463 HydrophobicContact CG-CE2 4.37Å; V425-Y463 PolarHBondContact N-O 2.99Å; Y463-L651 HydrophobicContact CD1-CD1 4.09Å; Y463-L651 HydrophobicContact CD1-CD2 4.05Å; Y463-L651 HydrophobicContact CD1-CG 3.85Å; Y463-L651 HydrophobicContact CD2-CD1 4.24Å; Y463-L651 HydrophobicContact CD2-CD2 3.37Å; Y463-L651 HydrophobicContact CD2-CG 4.05Å; Y463-L651 HydrophobicContact CE1-CD2 4.07Å; Y463-L651 HydrophobicContact CE1-CG 4.07Å; Y463-L651 HydrophobicContact CE2-CD2 3.39Å; Y463-L651 HydrophobicContact CE2-CG 4.25Å; Y463-L651 HydrophobicContact CG-CD1 3.77Å; Y463-L651 HydrophobicContact CG-CD2 3.7Å; Y463-L651 HydrophobicContact CG-CG 3.82Å
464Y93.7Very high91.8Very high7 Ų742 Ų423%0.02722%0.22CC..EExtended strand (participates in β ladder)trans-125.5134-176.4-65.3-96.2000109.1L375 V377 M422 W423 K424 L459 E460L375-Y464 PolarHBondContact N-O 3.3Å; L375-Y464 PolarHBondContact O-N 3.21Å; V377-Y464 HydrophobicContact CB-CD2 4.48Å; V377-Y464 HydrophobicContact CB-CE2 4.17Å; V377-Y464 HydrophobicContact CG2-CD2 3.84Å; V377-Y464 HydrophobicContact CG2-CE2 3.84Å; M422-Y464 HydrophobicContact CG-CD1 3.99Å; M422-Y464 HydrophobicContact SD-CD1 3.81Å; M422-Y464 HydrophobicContact SD-CE1 4.47Å; M422-Y464 HydrophobicContact SD-CG 4.38Å; W423-Y464 CarbonylContact O-C 3.53Å; W423-Y464 WeakPolarHBondContact O-CA 3.44Å; K424-Y464 HydrophobicContact CB-CD1 4.05Å; K424-Y464 HydrophobicContact CB-CE1 3.74Å; K424-Y464 HydrophobicContact CD-CE1 4.17Å; K424-Y464 HydrophobicContact CG-CD1 4.37Å; K424-Y464 HydrophobicContact CG-CE1 3.84Å; L459-Y464 HydrophobicContact CB-CE2 4.21Å; L459-Y464 HydrophobicContact CD1-CD1 4.26Å; L459-Y464 HydrophobicContact CD1-CD2 4.27Å; L459-Y464 HydrophobicContact CD1-CE1 4.19Å; L459-Y464 HydrophobicContact CD1-CE2 4.22Å; L459-Y464 HydrophobicContact CD1-CG 4.3Å; L459-Y464 HydrophobicContact CD2-CD1 4.46Å; L459-Y464 HydrophobicContact CD2-CE1 3.83Å; L459-Y464 HydrophobicContact CG-CE1 4.43Å; E460-Y464 PolarHBondContact N-OH 2.57Å; E460-Y464 WeakPolarHBondContact O-CE2 3.42Å; E460-Y464 PolarHBondContact O-OH 2.84Å
465L93.4Very high91.6Very high1 Ų141.4 Ų41.41%0.00522%0.217CC..EExtended strand (participates in β ladder)trans-96.9120.3173.4-174.969.5000109.1K372 W374 M422 W423 V425 L432 M435 I467K372-L465 HydrophobicContact CB-CD1 3.96Å; K372-L465 HydrophobicContact CG-CD1 4.11Å; K372-L465 HydrophobicContact CG-CD2 4.43Å; W374-L465 HydrophobicContact CZ3-CB 4.2Å; M422-L465 CarbonylContact C-O 3.51Å; M422-L465 VanDerWaalsContact CA-O 3.29Å; M422-L465 WeakPolarHBondContact CA-O 3.26Å; W423-L465 PolarHBondContact N-O 3.29Å; W423-L465 PolarHBondContact O-N 2.79Å; V425-L465 HydrophobicContact CG2-CB 4.23Å; L432-L465 HydrophobicContact CD1-CD2 3.82Å; M435-L465 HydrophobicContact CE-CB 4.48Å; M435-L465 HydrophobicContact CE-CD2 3.38Å; L465-I467 HydrophobicContact CD2-CD1 3.98Å; L465-I467 HydrophobicContact CD2-CG1 4.25Å; L465-I467 HydrophobicContact CG-CD1 4.47Å; L465-I467 HydrophobicContact CG-CG1 4.19Å
466L95.9Very high91.4Very high0 Ų045.1 Ų45.10%023%0.234CC..EExtended strand (participates in β ladder)trans-100.4130.6174.8-55.6173.6000109.7K372 F373 L375 V385 L420 H421 M422 L491K372-L466 WeakPolarHBondContact CA-O 3.44Å; F373-L466 HydrophobicContact CB-CB 4.21Å; F373-L466 PolarHBondContact N-O 3.12Å; F373-L466 PolarHBondContact O-N 2.86Å; L375-L466 HydrophobicContact CB-CD1 3.93Å; L375-L466 HydrophobicContact CB-CG 4.22Å; L375-L466 HydrophobicContact CD2-CD1 4.36Å; V385-L466 HydrophobicContact CG1-CD1 4.02Å; V385-L466 HydrophobicContact CG2-CD2 4.46Å; L420-L466 HydrophobicContact CD1-CB 4.32Å; H421-L466 WeakPolarHBondContact O-CA 3.5Å; M422-L466 HydrophobicContact CB-CD2 3.92Å; M422-L466 HydrophobicContact CE-CD2 3.49Å; M422-L466 VanDerWaalsContact CE-CD2 3.49Å; M422-L466 HydrophobicContact CG-CD2 3.71Å; M422-L466 HydrophobicContact SD-CD2 4.36Å; L466-L491 HydrophobicContact CD1-CD1 4.05Å
467I95.8Very high91.3Very high0 Ų044.9 Ų44.90%023%0.233CC..EExtended strand (participates in β ladder)trans-127.8100.4176-54-171.5000109.2Y367 N370 K372 H421 W423 L436 L465Y367-I467 HydrophobicContact CE1-CD1 4.32Å; Y367-I467 HydrophobicContact CE1-CG2 4.3Å; Y367-I467 HydrophobicContact CE2-CG2 4.35Å; N370-I467 HydrophobicContact CB-CG2 3.64Å; K372-I467 HydrophobicContact CG-CD1 4Å; K372-I467 HydrophobicContact CG-CG1 3.88Å; H421-I467 PolarHBondContact N-O 2.75Å; H421-I467 VanDerWaalsContact N-O 3.08Å; H421-I467 PolarHBondContact O-N 3.4Å; W423-I467 HydrophobicContact CE3-CD1 4.5Å; W423-I467 HydrophobicContact CH2-CD1 4.44Å; W423-I467 HydrophobicContact CZ3-CB 4.16Å; W423-I467 HydrophobicContact CZ3-CD1 3.92Å; W423-I467 HydrophobicContact CZ3-CG1 4.01Å; L436-I467 HydrophobicContact CD2-CD1 3.46Å; L436-I467 VanDerWaalsContact CD2-CD1 3.46Å; L465-I467 HydrophobicContact CD2-CD1 3.98Å; L465-I467 HydrophobicContact CD2-CG1 4.25Å; L465-I467 HydrophobicContact CG-CD1 4.47Å; L465-I467 HydrophobicContact CG-CG1 4.19Å
468P97.1Very high91.4Very high0 Ų045.5 Ų45.50%024%0.235CC..EExtended strand (participates in β ladder)trans-75.9138.6167.333.1-37.3000110.6W352 P371 F373 L387 A419 L420 F479 I481W352-P468 HydrophobicContact CZ2-CB 3.92Å; W352-P468 PolarHBondContact NE1-O 3.32Å; P371-P468 HydrophobicContact CB-CG 4.4Å; P371-P468 WeakPolarHBondContact O-CD 3.35Å; F373-P468 HydrophobicContact CD2-CG 4.18Å; F373-P468 HydrophobicContact CE2-CG 3.69Å; L387-P468 HydrophobicContact CD1-CB 3.56Å; L387-P468 HydrophobicContact CD1-CG 4.45Å; L387-P468 HydrophobicContact CD2-CB 3.54Å; L387-P468 HydrophobicContact CG-CB 4.18Å; A419-P468 WeakPolarHBondContact O-CA 2.94Å; L420-P468 HydrophobicContact CD1-CB 4.18Å; P468-F479 HydrophobicContact CB-CE2 4.12Å; P468-F479 HydrophobicContact CB-CZ 4.23Å; P468-F479 HydrophobicContact CG-CE1 4.47Å; P468-F479 HydrophobicContact CG-CE2 3.59Å; P468-F479 HydrophobicContact CG-CZ 3.53Å; P468-I481 HydrophobicContact CB-CD1 4.16Å; P468-I481 HydrophobicContact CG-CD1 3.75Å
469S94.6Very high91.6Very high0 Ų040.6 Ų40.60%020%0.204CC..EExtended strand (participates in β ladder)trans-143.6147.6-177.259.60000111.9G360 I418 A419 H447G360-S469 WeakPolarHBondContact O-CB 3.41Å; I418-S469 CarbonylContact C-O 3.54Å; I418-S469 WeakPolarHBondContact CA-O 3.49Å; A419-S469 PolarHBondContact N-O 3.16Å; A419-S469 PolarHBondContact O-N 3.08Å; H447-S469 PolarHBondContact NE2-OG 2.86Å; H447-S469 VanDerWaalsContact NE2-OG 3.12Å
470T94.6Very high91.6Very high0 Ų040.3 Ų40.30%020%0.202CC..EExtended strand (participates in β ladder)trans-81.6161.8160.254.30000110.3W352 G360 S361 Q416 A417 I418 H447 Q472 A475W352-T470 HydrophobicContact CD2-CG2 3.73Å; W352-T470 HydrophobicContact CE3-CG2 3.8Å; W352-T470 HydrophobicContact CG-CG2 4.1Å; W352-T470 HydrophobicContact CH2-CG2 4.48Å; W352-T470 HydrophobicContact CZ2-CG2 4.41Å; W352-T470 HydrophobicContact CZ3-CG2 4.19Å; G360-T470 CarbonylContact C-O 3.54Å; G360-T470 VanDerWaalsContact CA-O 3.31Å; G360-T470 WeakPolarHBondContact CA-O 3.48Å; S361-T470 PolarHBondContact N-O 3.46Å; Q416-T470 HydrophobicContact CB-CG2 3.85Å; Q416-T470 HydrophobicContact CG-CG2 4.29Å; A417-T470 CarbonylContact O-C 3.49Å; A417-T470 VanDerWaalsContact O-CA 3.25Å; A417-T470 WeakPolarHBondContact O-CA 3.16Å; I418-T470 HydrophobicContact CG2-CG2 4.33Å; H447-T470 PolarHBondContact NE2-O 3.21Å; T470-Q472 PolarHBondContact OG1-O 2.92Å; T470-A475 HydrophobicContact CG2-CB 3.94Å
471Y87.6Confident91.7Very high124 Ų12435.5 Ų35.549%0.48618%0.18SC..SBendtrans-69.7-54.8175.2-177.9-103.6000110.7S361 A417 H447S361-Y471 WeakPolarHBondContact CB-O 3.44Å; S361-Y471 PolarHBondContact N-O 3.38Å; A417-Y471 PolarHBondContact O-N 3.49Å; H447-Y471 HydrophobicContact CB-CD2 4.02Å; H447-Y471 HydrophobicContact CB-CG 4.32Å; H447-Y471 VanDerWaalsContact CD2-CA 3.44Å; H447-Y471 WeakPolarHBondContact CD2-CA 3.4Å; H447-Y471 PolarHBondContact CD2-N 3.2Å; H447-Y471 AromaticContact CG-CD2 3.87Å; H447-Y471 AromaticContact ND1-CD2 3.81Å
472Q86.7Confident91.9Very high120 Ų12032.8 Ų32.856%0.56116%0.162SC*.SBendtrans-81.4135.6179-64.9-174.9-12.800111.1T470 A475T470-Q472 PolarHBondContact OG1-O 2.92Å; Q472-A475 HydrophobicContact CB-CB 4.39Å; Q472-A475 VanDerWaalsContact O-CB 3.3Å; Q472-A475 WeakPolarHBondContact O-CB 3.32Å
473P82.8Confident92.2Very high72 Ų7231.8 Ų31.847%0.46815%0.152SC..THydrogen-bonded Turntrans-66.1149169.227.2-32.5000111.6T364 A475T364-P473 HydrophobicContact CG2-CB 3.93Å; T364-P473 HydrophobicContact CG2-CG 3.86Å; P473-A475 PolarHBondContact O-N 3.12Å
474G83.7Confident92.5Very high22 Ų2230.1 Ų30.123%0.22715%0.146CC..THydrogen-bonded Turntrans74.8-3.2-177.100000114.8A358 E476A358-G474 PolarHBondContact O-N 2.95Å; G474-E476 PolarHBondContact O-N 3.29Å
475A87.4Confident92.6Very high11 Ų1129.8 Ų29.89%0.09114%0.144CC..  trans-68.1121.5175.500000111.4W352 A358 Q416 T470 Q472 P473W352-A475 WeakPolarHBondContact CB-O 3.5Å; A358-A475 WeakPolarHBondContact CB-O 3.12Å; Q416-A475 HydrophobicContact CG-CB 4.32Å; Q416-A475 VanDerWaalsContact OE1-CB 3.3Å; T470-A475 HydrophobicContact CG2-CB 3.94Å; Q472-A475 HydrophobicContact CB-CB 4.39Å; Q472-A475 VanDerWaalsContact O-CB 3.3Å; Q472-A475 WeakPolarHBondContact O-CB 3.32Å; P473-A475 PolarHBondContact O-N 3.12Å
476E87.8Confident92.8Very high87 Ų8731.5 Ų31.541%0.40716%0.156SC..  trans-100.3132.1-176-58.4-174.411400111.7W352 K354 K392 G474W352-E476 WeakPolarHBondContact O-CA 3.48Å; K354-E476 HydrophobicContact CB-CG 3.79Å; K354-E476 WeakPolarHBondContact CB-OE1 3.45Å; K354-E476 PolarHBondContact N-OE1 3.18Å; K392-E476 WeakPolarHBondContact CE-O 3.3Å; K392-E476 PolarHBondContact NZ-O 3.3Å; G474-E476 PolarHBondContact O-N 3.29Å
477A90.1Very high92.6Very high12 Ų1231.7 Ų31.710%0.09916%0.158CC..EExtended strand (participates in β ladder)trans-160.7155.2167.500000110.5R351 W352 Q416R351-A477 CarbonylContact C-O 3.44Å; R351-A477 WeakPolarHBondContact CA-O 3.34Å; W352-A477 HydrophobicContact CE3-CB 3.83Å; W352-A477 HydrophobicContact CZ3-CB 4.08Å; W352-A477 PolarHBondContact N-O 2.88Å; W352-A477 PolarHBondContact O-N 3.29Å; Q416-A477 HydrophobicContact CG-CB 4.09Å
478R92.7Very high92.4Very high141 Ų14133.9 Ų33.953%0.53217%0.172SC..EExtended strand (participates in β ladder)trans-85.3146.9166.6-67.8173.961.8176.7-2.9108.8R351 Q389 H390R351-R478 HydrophobicContact CB-CG 4.32Å; Q389-R478 WeakPolarHBondContact CA-O 3.27Å; H390-R478 HydrophobicContact CB-CB 4.04Å; H390-R478 PolarHBondContact N-O 3.14Å; H390-R478 PolarHBondContact ND1-O 3.44Å
479F95.1Very high92.2Very high0 Ų034.6 Ų34.60%018%0.176CC..EExtended strand (participates in β ladder)trans-147.4164.2177.168.4-93.7000112.6A349 S350 W352 P371 F373 L387 L388 P468 I481A349-F479 WeakPolarHBondContact CA-O 3.12Å; S350-F479 VanDerWaalsContact CB-CZ 3.46Å; S350-F479 PolarHBondContact N-O 3.11Å; S350-F479 PolarHBondContact O-N 3.3Å; S350-F479 VanDerWaalsContact O-O 3.09Å; W352-F479 AromaticContact CD2-CD1 3.63Å; W352-F479 HydrophobicContact CD2-CD1 3.63Å; W352-F479 AromaticContact CD2-CE1 3.7Å; W352-F479 HydrophobicContact CD2-CE1 3.7Å; W352-F479 AromaticContact CE2-CD1 3.78Å; W352-F479 AromaticContact CE2-CE1 3.64Å; W352-F479 AromaticContact CE3-CD1 3.47Å; W352-F479 HydrophobicContact CE3-CD1 3.47Å; W352-F479 VanDerWaalsContact CE3-CD1 3.47Å; W352-F479 HydrophobicContact CE3-CE1 4.06Å; W352-F479 HydrophobicContact CE3-CG 4.37Å; W352-F479 HydrophobicContact CG-CD1 4.44Å; W352-F479 HydrophobicContact CG-CE1 4.16Å; W352-F479 HydrophobicContact CH2-CB 3.99Å; W352-F479 AromaticContact CH2-CD1 3.69Å; W352-F479 HydrophobicContact CH2-CD1 3.69Å; W352-F479 HydrophobicContact CH2-CE1 4.32Å; W352-F479 AromaticContact CH2-CG 3.91Å; W352-F479 HydrophobicContact CH2-CG 3.91Å; W352-F479 AromaticContact CZ2-CD1 3.84Å; W352-F479 HydrophobicContact CZ2-CD1 3.84Å; W352-F479 AromaticContact CZ2-CE1 4Å; W352-F479 HydrophobicContact CZ2-CE1 4Å; W352-F479 HydrophobicContact CZ2-CG 4.29Å; W352-F479 HydrophobicContact CZ3-CB 3.83Å; W352-F479 AromaticContact CZ3-CD1 3.51Å; W352-F479 HydrophobicContact CZ3-CD1 3.51Å; W352-F479 HydrophobicContact CZ3-CE1 4.36Å; W352-F479 AromaticContact CZ3-CG 3.96Å; W352-F479 HydrophobicContact CZ3-CG 3.96Å; W352-F479 AromaticContact NE1-CE1 3.98Å; P371-F479 HydrophobicContact CB-CZ 3.96Å; P371-F479 HydrophobicContact CG-CE1 4.04Å; P371-F479 HydrophobicContact CG-CZ 3.88Å; F373-F479 AromaticContact CE2-CE2 3.97Å; F373-F479 HydrophobicContact CE2-CE2 3.97Å; F373-F479 HydrophobicContact CE2-CZ 4.07Å; F373-F479 AromaticContact CZ-CE2 3.9Å; F373-F479 HydrophobicContact CZ-CE2 3.9Å; F373-F479 HydrophobicContact CZ-CZ 4.09Å; L387-F479 HydrophobicContact CD1-CB 4.02Å; L387-F479 HydrophobicContact CD1-CD2 3.33Å; L387-F479 HydrophobicContact CD1-CE2 3.93Å; L387-F479 HydrophobicContact CD1-CG 3.83Å; L388-F479 CarbonylContact O-C 3.24Å; L388-F479 WeakPolarHBondContact O-CA 3.45Å; L388-F479 WeakPolarHBondContact O-CB 3.22Å; P468-F479 HydrophobicContact CB-CE2 4.12Å; P468-F479 HydrophobicContact CB-CZ 4.23Å; P468-F479 HydrophobicContact CG-CE1 4.47Å; P468-F479 HydrophobicContact CG-CE2 3.59Å; P468-F479 HydrophobicContact CG-CZ 3.53Å; F479-I481 HydrophobicContact CD2-CG1 4.38Å; F479-I481 HydrophobicContact CE2-CD1 4.35Å; F479-I481 HydrophobicContact CE2-CG1 4.19Å
480L95.6Very high91.8Very high5 Ų537 Ų373%0.02619%0.194CC..EExtended strand (participates in β ladder)trans-123125.7174.5-172.571.2000107.8W115 Q347 A349 L388 R482W115-L480 HydrophobicContact CH2-CD2 4.21Å; W115-L480 HydrophobicContact CZ2-CD2 4.24Å; Q347-L480 HydrophobicContact CB-CD1 4.1Å; Q347-L480 HydrophobicContact CB-CD2 4.49Å; Q347-L480 HydrophobicContact CB-CG 4.37Å; Q347-L480 HydrophobicContact CG-CD1 4.47Å; A349-L480 HydrophobicContact CB-CD1 4.14Å; L388-L480 HydrophobicContact CB-CB 4.45Å; L388-L480 PolarHBondContact N-O 3.1Å; L388-L480 PolarHBondContact O-N 3.23Å; L480-R482 HydrophobicContact CD2-CG 3.72Å; L480-R482 HydrophobicContact CG-CG 3.86Å
481I96.6Very high91.6Very high0 Ų038.1 Ų38.10%020%0.199CC..EExtended strand (participates in β ladder)trans-91.4130.2163-86179.5000107.8Q347 L348 F373 V385 S386 L387 L420 P468 F479 V483 L491Q347-I481 CarbonylContact C-O 3.56Å; Q347-I481 WeakPolarHBondContact CA-O 3.01Å; L348-I481 PolarHBondContact N-O 3.04Å; L348-I481 PolarHBondContact O-N 2.96Å; F373-I481 HydrophobicContact CD2-CD1 3.52Å; F373-I481 HydrophobicContact CE2-CD1 3.69Å; F373-I481 HydrophobicContact CG-CD1 4.07Å; F373-I481 HydrophobicContact CZ-CD1 4.34Å; V385-I481 HydrophobicContact CG1-CG2 4.28Å; S386-I481 CarbonylContact O-C 3.57Å; S386-I481 WeakPolarHBondContact O-CA 3.33Å; L387-I481 HydrophobicContact CD1-CG1 3.83Å; L420-I481 HydrophobicContact CD1-CD1 4.26Å; P468-I481 HydrophobicContact CB-CD1 4.16Å; P468-I481 HydrophobicContact CG-CD1 3.75Å; F479-I481 HydrophobicContact CD2-CG1 4.38Å; F479-I481 HydrophobicContact CE2-CD1 4.35Å; F479-I481 HydrophobicContact CE2-CG1 4.19Å; I481-V483 HydrophobicContact CG2-CG2 4.32Å; I481-L491 HydrophobicContact CG2-CD1 4.32Å; I481-L491 HydrophobicContact CG2-CD2 3.84Å
482R97.1Very high91.5Very high3 Ų334.9 Ų34.91%0.01120%0.195CC..EExtended strand (participates in β ladder)trans-120.3136.7174.5-52.8-172.8-69.7172.24.4108.9W115 G180 G181 H346 Q347 V385 S386 E452 L480 F484W115-R482 VanDerWaalsContact CZ2-NH1 3.33Å; G180-R482 PolarHBondContact O-NH1 2.97Å; G181-R482 VanDerWaalsContact O-CZ 3.31Å; G181-R482 PolarHBondContact O-NH1 2.94Å; G181-R482 PolarHBondContact O-NH2 2.72Å; H346-R482 CarbonylContact O-C 3.55Å; H346-R482 VanDerWaalsContact O-CA 3.31Å; H346-R482 WeakPolarHBondContact O-CA 3.38Å; Q347-R482 HydrophobicContact CB-CG 4.16Å; V385-R482 CarbonylContact C-O 3.43Å; V385-R482 VanDerWaalsContact CA-O 3.31Å; V385-R482 WeakPolarHBondContact CA-O 3.01Å; S386-R482 PolarHBondContact N-O 2.87Å; S386-R482 PolarHBondContact O-N 3.21Å; S386-R482 PolarHBondContact OG-NE 3.2Å; E452-R482 IonicContact OE1-CZ 2.65Å; E452-R482 IonicContact OE1-NE 2.77Å; E452-R482 PolarHBondContact OE1-NE 2.86Å; E452-R482 IonicContact OE1-NH2 3.59Å; E452-R482 PolarHBondContact OE1-NH2 3.16Å; E452-R482 IonicContact OE2-NH2 3.87Å; E452-R482 PolarHBondContact OE2-NH2 3.26Å; L480-R482 HydrophobicContact CD2-CG 3.72Å; L480-R482 HydrophobicContact CG-CG 3.86Å; R482-F484 HydrophobicContact CB-CD2 4.45Å; R482-F484 HydrophobicContact CB-CE2 3.66Å; R482-F484 HydrophobicContact CB-CZ 4.19Å
483V97.3Very high91.2Very high0 Ų031.9 Ų31.90%019%0.19CC..EExtended strand (participates in β ladder)trans-123.6128.3175.9176.70000107.8S345 H346 L375 V383 L384 V385 I481 L491S345-V483 CarbonylContact C-O 3.49Å; S345-V483 VanDerWaalsContact CA-O 3.23Å; S345-V483 WeakPolarHBondContact CA-O 3.37Å; H346-V483 HydrophobicContact CB-CB 4.41Å; H346-V483 PolarHBondContact N-O 3.22Å; H346-V483 PolarHBondContact O-N 3.36Å; L375-V483 HydrophobicContact CD1-CG1 3.9Å; L375-V483 HydrophobicContact CD1-CG2 4.38Å; V383-V483 HydrophobicContact CG1-CG1 3.84Å; L384-V483 CarbonylContact O-C 3.48Å; L384-V483 WeakPolarHBondContact O-CA 3.39Å; V385-V483 HydrophobicContact CG1-CG2 4.06Å; V385-V483 HydrophobicContact CG2-CG2 4.2Å; I481-V483 HydrophobicContact CG2-CG2 4.32Å; V483-L491 HydrophobicContact CG2-CD1 4.03Å; V483-L491 HydrophobicContact CG2-CD2 3.94Å; V483-L491 HydrophobicContact CG2-CG 4.41Å
484F97.4Very high90.7Very high27 Ų2729.6 Ų29.612%0.11817%0.174CC..EExtended strand (participates in β ladder)trans-122.8133.7173.5-55.5-93.8000107.9V182 L333 L342 H344 L384 R482V182-F484 HydrophobicContact CG2-CD2 4.16Å; V182-F484 HydrophobicContact CG2-CE2 3.58Å; V182-F484 HydrophobicContact CG2-CZ 4.14Å; L333-F484 HydrophobicContact CB-CD1 4.11Å; L333-F484 HydrophobicContact CD2-CB 4.32Å; L333-F484 HydrophobicContact CD2-CD1 3.99Å; L333-F484 HydrophobicContact CD2-CD2 4.09Å; L333-F484 HydrophobicContact CD2-CE1 4.28Å; L333-F484 HydrophobicContact CD2-CE2 4.36Å; L333-F484 HydrophobicContact CD2-CG 3.88Å; L333-F484 HydrophobicContact CD2-CZ 4.45Å; L342-F484 HydrophobicContact CB-CB 4.01Å; L342-F484 HydrophobicContact CD1-CB 3.61Å; L342-F484 HydrophobicContact CG-CB 4.45Å; H344-F484 CarbonylContact O-C 3.21Å; H344-F484 VanDerWaalsContact O-CA 3.28Å; H344-F484 WeakPolarHBondContact O-CA 3.28Å; L384-F484 HydrophobicContact CB-CB 4.36Å; L384-F484 HydrophobicContact CD2-CD2 3.63Å; L384-F484 HydrophobicContact CD2-CE2 4.32Å; L384-F484 HydrophobicContact CD2-CG 4.5Å; L384-F484 PolarHBondContact N-O 2.98Å; L384-F484 PolarHBondContact O-N 3.22Å; R482-F484 HydrophobicContact CB-CD2 4.45Å; R482-F484 HydrophobicContact CB-CE2 3.66Å; R482-F484 HydrophobicContact CB-CZ 4.19Å
485S96.4Very high89.3Confident0 Ų036.1 Ų36.10%020%0.196CC..EExtended strand (participates in β ladder)trans-146.2147.8-177.5-174.40000113.3L342 T343 H344 E382 V383 S487L342-S485 CarbonylContact C-O 3.59Å; L342-S485 VanDerWaalsContact C-O 3.24Å; L342-S485 WeakPolarHBondContact CA-O 3.43Å; T343-S485 PolarHBondContact N-O 3.35Å; H344-S485 PolarHBondContact N-O 3.36Å; H344-S485 PolarHBondContact O-N 2.99Å; E382-S485 WeakPolarHBondContact O-CA 3.37Å; E382-S485 WeakPolarHBondContact O-CB 3.39Å; E382-S485 PolarHBondContact O-OG 2.97Å; V383-S485 WeakPolarHBondContact CG2-OG 3.42Å; S485-S487 VanDerWaalsContact C-N 3.25Å; S485-S487 WeakPolarHBondContact CB-O 3.17Å; S485-S487 PolarHBondContact OG-N 3.1Å; S485-S487 PolarHBondContact OG-O 2.93Å; S485-S487 VanDerWaalsContact OG-O 3.11Å
486S96.1Very high87.1Confident37 Ų3739.3 Ų39.326%0.25922%0.218SC..SBendtrans-75.2-13.9168.970.80000112.9E382E382-S486 PolarHBondContact N-OG 3.43Å; E382-S486 PolarHBondContact O-N 3.17Å
487S92Very high84.5Confident5 Ų539.3 Ų39.34%0.03523%0.226CC..SBendtrans-123.2159.8179.970.40000112.1H344 E379 S485 T489H344-S487 PolarHBondContact CD2-O 3.46Å; E379-S487 WeakPolarHBondContact O-CB 3.25Å; E379-S487 PolarHBondContact O-OG 2.86Å; S485-S487 VanDerWaalsContact C-N 3.25Å; S485-S487 WeakPolarHBondContact CB-O 3.17Å; S485-S487 PolarHBondContact OG-N 3.1Å; S485-S487 PolarHBondContact OG-O 2.93Å; S485-S487 VanDerWaalsContact OG-O 3.11Å; S487-T489 PolarHBondContact O-N 2.85Å
488P91.3Very high81.5Confident46 Ų4642.7 Ų42.730%0.29925%0.254SS..  trans-60.6125.3-179.9-23.533000111.6C378C378-P488 HydrophobicContact CB-CB 4.13Å; C378-P488 VanDerWaalsContact CB-O 3.29Å; C378-P488 WeakPolarHBondContact CB-O 3.08Å; C378-P488 PolarHBondContact N-O 3.5Å
489T92.4Very high78.6Confident14 Ų1440 Ų409%0.08625%0.254CS..EExtended strand (participates in β ladder)trans-126.6166.1178.453.30000111.5H346 L375 R376 V377 V383 S487H346-T489 PolarHBondContact CD2-OG1 3.4Å; H346-T489 PolarHBondContact NE2-O 3Å; H346-T489 PolarHBondContact NE2-OG1 2.89Å; L375-T489 HydrophobicContact CD1-CG2 4.25Å; R376-T489 CarbonylContact O-C 3.53Å; R376-T489 WeakPolarHBondContact O-CA 3.35Å; R376-T489 WeakPolarHBondContact O-CB 3.48Å; V377-T489 HydrophobicContact CG2-CG2 4.2Å; V383-T489 HydrophobicContact CG2-CG2 4.39Å; S487-T489 PolarHBondContact O-N 2.85Å
490S86.9Confident75.5Confident52 Ų5244.8 Ų44.836%0.36429%0.288SS..EExtended strand (participates in β ladder)trans-138.4139.3163.679.60000110.7L375 R376L375-S490 CarbonylContact C-O 3.5Å; L375-S490 WeakPolarHBondContact CA-O 3.41Å; R376-S490 WeakPolarHBondContact CB-OG 3.3Å; R376-S490 PolarHBondContact N-O 2.92Å; R376-S490 PolarHBondContact O-N 3.22Å
491L91.7Very high72.2Confident23 Ų2349.2 Ų49.212%0.1231%0.311CS..EExtended strand (participates in β ladder)trans-119130.9-179.5-17969000109.6H346 L348 F373 W374 L466 I481 V483H346-L491 HydrophobicContact CB-CB 3.73Å; H346-L491 HydrophobicContact CB-CD2 3.95Å; L348-L491 HydrophobicContact CB-CD2 4.26Å; L348-L491 HydrophobicContact CD1-CD2 3.89Å; L348-L491 HydrophobicContact CD1-CG 3.67Å; L348-L491 HydrophobicContact CG-CD2 3.83Å; L348-L491 HydrophobicContact CG-CG 4.16Å; F373-L491 HydrophobicContact CB-CD1 4.11Å; W374-L491 CarbonylContact O-C 3.58Å; W374-L491 WeakPolarHBondContact O-CA 3.46Å; L466-L491 HydrophobicContact CD1-CD1 4.05Å; I481-L491 HydrophobicContact CG2-CD1 4.32Å; I481-L491 HydrophobicContact CG2-CD2 3.84Å; V483-L491 HydrophobicContact CG2-CD1 4.03Å; V483-L491 HydrophobicContact CG2-CD2 3.94Å; V483-L491 HydrophobicContact CG2-CG 4.41Å
492S84.1Confident69Low55 Ų5553 Ų5339%0.38534%0.335SS..EExtended strand (participates in β ladder)trans-143.9142175.658.30000111.7F373 W374F373-S492 CarbonylContact C-O 3.52Å; F373-S492 VanDerWaalsContact CA-O 3.3Å; F373-S492 WeakPolarHBondContact CA-O 3.45Å; W374-S492 PolarHBondContact N-O 3.36Å; W374-S492 PolarHBondContact O-N 3.34Å
493A80.8Confident65.8Low57 Ų5761.4 Ų61.447%0.47138%0.38SS..EExtended strand (participates in β ladder)trans-71.3133.6171.600000109.5L348 F373 K495L348-A493 HydrophobicContact CD1-CB 4.38Å; F373-A493 HydrophobicContact CD1-CB 3.91Å; F373-A493 HydrophobicContact CE1-CB 3.89Å; A493-K495 PolarHBondContact O-N 3.42Å
494L72.3Confident62.5Low24 Ų2466 Ų6613%0.12641%0.408CS..  trans-69.5117.9166.4-167.761.3000106.5K372 S496K372-L494 HydrophobicContact CB-CB 3.76Å; K372-L494 HydrophobicContact CB-CD2 3.83Å; K372-L494 HydrophobicContact CB-CG 4.44Å; K372-L494 HydrophobicContact CD-CD2 3.88Å; K372-L494 HydrophobicContact CG-CD2 4.46Å; K372-L494 WeakPolarHBondContact O-CB 3.42Å; K372-L494 PolarHBondContact O-N 2.7Å; L494-S496 VanDerWaalsContact C-N 3.29Å; L494-S496 PolarHBondContact O-N 3.22Å
495K54Low59.6Low159 Ų15970.6 Ų70.669%0.69144%0.443SS*.  trans-62.698.9170.2-65.9-176.6-177.9-178.90106.7A493A493-K495 PolarHBondContact O-N 3.42Å
496S40.8Very low56.8Low78 Ų7873.9 Ų73.955%0.54546%0.461SS..PPolyproline II helixtrans-57.7134.2160.435.30000106.4L494L494-S496 VanDerWaalsContact C-N 3.29Å; L494-S496 PolarHBondContact O-N 3.22Å
497P33.2Very low54.7Low88 Ų8873.5 Ų73.557%0.57146%0.463SS*.PPolyproline II helixtrans-51.4147.9166.220.5-29.1000108.2
498A27.9Very low52.9Low83 Ų8379.8 Ų79.869%0.68649%0.492SS*.SBendtrans-49.6152.2179.300000110.3S500A498-S500 PolarHBondContact O-N 3.01Å
499P31.1Very low51.8Low83 Ų8380.4 Ų80.454%0.53949%0.488SS..  trans-45.5111.3-166.4-24.330.8000113.7H356 L501H356-P499 VanDerWaalsContact CD2-CA 3.42Å; H356-P499 WeakPolarHBondContact CD2-CA 3.47Å; H356-P499 WeakPolarHBondContact CD2-CB 3.42Å; H356-P499 VanDerWaalsContact NE2-CA 3.3Å; H356-P499 WeakPolarHBondContact NE2-CA 3.37Å; P499-L501 PolarHBondContact O-N 2.94Å
500S30.2Very low50.8Low102 Ų10282.8 Ų82.871%0.71350%0.498SS*.  trans-64.9114.2147.943.40000105.9A498A498-S500 PolarHBondContact O-N 3.01Å
501L27.7Very low50.3Low98 Ų9883.1 Ų83.151%0.51350%0.499SS..  trans-55.7157.5174.2-79155.6000110.3P499 L503P499-L501 PolarHBondContact O-N 2.94Å; L501-L503 PolarHBondContact O-N 2.82Å
502P28.9Very low49.4Very low78 Ų7883.9 Ų83.951%0.50651%0.506SS..  trans-52.4138.2-170.6-9.59.3000112.2T504P502-T504 PolarHBondContact O-N 3.1Å
503L29Very low49.2Very low181 Ų18187.8 Ų87.895%0.94852%0.516SS*.  trans-62.383159.6-93.2113.5000108.7L501L501-L503 PolarHBondContact O-N 2.82Å
504T27.9Very low49.1Very low95 Ų9587.5 Ų87.558%0.58350%0.504SS*.  trans-85.3139.1144.350.30000106.4P502 D506P502-T504 PolarHBondContact O-N 3.1Å; T504-D506 PolarHBondContact O-N 2.86Å
505S36.5Very low49.8Very low124 Ų12496 Ų9687%0.86754%0.535SS*.SBendtrans-62.551.5-169.355.10000115.7
506D39.2Very low51.5Low69 Ų6989.3 Ų89.337%0.36951%0.51SS..SBendtrans-14978.1-162.7-109.3-38.6000111.1T504 K639T504-D506 PolarHBondContact O-N 2.86Å; D506-K639 WeakPolarHBondContact O-CE 3.44Å; D506-K639 PolarHBondContact O-NZ 3.02Å; D506-K639 IonicContact OD1-NZ 2.79Å; D506-K639 PolarHBondContact OD1-NZ 3.45Å
507G50.8Low54Low30 Ų3087.6 Ų87.631%0.30950%0.498SS..  trans59147.5168.300000116.7W509 K639G507-W509 VanDerWaalsContact O-CD1 3.29Å; G507-K639 VanDerWaalsContact CA-CE 3.49Å
508E54.9Low57Low136 Ų13683.5 Ų83.564%0.63647%0.472SS*.EExtended strand (participates in β ladder)trans-66.7147173.1-73-70.1154.300110.1K639 I640E508-K639 CarbonylContact O-C 3.57Å; E508-K639 WeakPolarHBondContact O-CA 3.4Å; E508-I640 HydrophobicContact CB-CG1 4.31Å; E508-I640 PolarHBondContact N-O 3.01Å; E508-I640 PolarHBondContact O-N 2.86Å; E508-I640 VanDerWaalsContact O-O 3.08Å
509W67.7Low60.2Low60 Ų6082.6 Ų82.623%0.22745%0.454CS..EExtended strand (participates in β ladder)trans-113.2121.1178.4-71.476.4000110.3G507 V553 N554 R556 A637 R638 K639G507-W509 VanDerWaalsContact O-CD1 3.29Å; W509-V553 HydrophobicContact CH2-CB 4.47Å; W509-V553 HydrophobicContact CH2-CG1 3.93Å; W509-V553 WeakPolarHBondContact CH2-O 3.34Å; W509-V553 VanDerWaalsContact CZ2-O 3.24Å; W509-V553 WeakPolarHBondContact CZ2-O 3.3Å; W509-N554 VanDerWaalsContact CH2-C 3.44Å; W509-N554 VanDerWaalsContact CZ3-C 3.41Å; W509-N554 WeakPolarHBondContact CZ3-O 3.45Å; W509-R556 HydrophobicContact CH2-CG 4.09Å; W509-R556 HydrophobicContact CZ3-CB 4.48Å; W509-R556 HydrophobicContact CZ3-CG 3.92Å; W509-A637 HydrophobicContact CE3-CB 3.9Å; W509-R638 CarbonylContact C-O 3.55Å; W509-R638 VanDerWaalsContact CA-O 3.3Å; W509-R638 WeakPolarHBondContact CA-O 3.42Å; W509-K639 HydrophobicContact CD2-CB 4.38Å; W509-K639 HydrophobicContact CE3-CB 4.49Å; W509-K639 HydrophobicContact CZ2-CB 4.41Å; W509-K639 HydrophobicContact CZ2-CD 4.46Å
510E70.6Confident63.2Low63 Ų6384.9 Ų84.929%0.29446%0.458SS..EExtended strand (participates in β ladder)trans-87.4121.5170.7-174.6178-152.400109.8A637 R638 I640E510-A637 CarbonylContact O-C 3.33Å; E510-A637 VanDerWaalsContact O-CA 3.3Å; E510-A637 WeakPolarHBondContact O-CA 3.46Å; E510-R638 HydrophobicContact CB-CG 4.11Å; E510-R638 PolarHBondContact N-O 3.01Å; E510-R638 PolarHBondContact O-N 3.29Å; E510-R638 IonicContact OE1-NH2 3.71Å; E510-R638 IonicContact OE2-CZ 3.13Å; E510-R638 IonicContact OE2-NE 2.77Å; E510-R638 PolarHBondContact OE2-NE 3.45Å; E510-R638 IonicContact OE2-NH2 2.68Å; E510-R638 PolarHBondContact OE2-NH2 3.29Å; E510-I640 HydrophobicContact CB-CD1 3.75Å; E510-I640 HydrophobicContact CB-CG1 3.89Å; E510-I640 HydrophobicContact CB-CG2 3.87Å; E510-I640 HydrophobicContact CG-CD1 4.45Å
511T77.3Confident65.8Low60 Ų6082.7 Ų82.737%0.36845%0.451SS..EExtended strand (participates in β ladder)trans-107.8123.1178.7-53.10000111.2F513 S635 L636 A637T511-F513 HydrophobicContact CG2-CE1 4.21Å; T511-F513 HydrophobicContact CG2-CE2 3.9Å; T511-F513 HydrophobicContact CG2-CZ 3.71Å; T511-S635 WeakPolarHBondContact CG2-OG 3.25Å; T511-L636 CarbonylContact C-O 3.48Å; T511-L636 VanDerWaalsContact CA-O 3.29Å; T511-L636 WeakPolarHBondContact CA-O 3.21Å; T511-A637 HydrophobicContact CG2-CB 4.3Å; T511-A637 WeakPolarHBondContact OG1-CB 3.28Å
512S72.8Confident68.8Low39 Ų3986.4 Ų86.427%0.27346%0.459SS..EExtended strand (participates in β ladder)trans-106.3141.1173-62.10000110.2L636S512-L636 PolarHBondContact N-O 3.02Å; S512-L636 PolarHBondContact O-N 3.2Å
513F80.8Confident71.8Confident136 Ų13684.2 Ų84.260%0.59644%0.444SS*.EExtended strand (participates in β ladder)trans-113.9128.3177.8-62.7-86.5000110.7T511 I633 I634 S635T511-F513 HydrophobicContact CG2-CE1 4.21Å; T511-F513 HydrophobicContact CG2-CE2 3.9Å; T511-F513 HydrophobicContact CG2-CZ 3.71Å; F513-I633 HydrophobicContact CD1-CG2 4.19Å; F513-I634 CarbonylContact C-O 3.56Å; F513-I634 VanDerWaalsContact CA-O 3.29Å; F513-I634 WeakPolarHBondContact CA-O 3.26Å; F513-S635 WeakPolarHBondContact CE1-OG 3.33Å
514F77.6Confident74.9Confident52 Ų5275.7 Ų75.723%0.22840%0.4CS..EExtended strand (participates in β ladder)trans-114.3121.6174.3-54.9-81.8000109.4F539 I633 I634 L636F514-F539 HydrophobicContact CB-CD1 3.5Å; F514-F539 VanDerWaalsContact CB-CD1 3.5Å; F514-F539 HydrophobicContact CB-CE1 3.73Å; F514-F539 HydrophobicContact CB-CG 3.96Å; F514-F539 HydrophobicContact CB-CZ 4.38Å; F514-F539 HydrophobicContact CD1-CB 4.34Å; F514-F539 AromaticContact CD1-CD1 3.78Å; F514-F539 HydrophobicContact CD1-CD1 3.78Å; F514-F539 HydrophobicContact CD1-CG 4.4Å; F514-F539 HydrophobicContact CD2-CB 4.32Å; F514-F539 HydrophobicContact CG-CB 4.14Å; F514-F539 AromaticContact CG-CD1 3.75Å; F514-F539 HydrophobicContact CG-CD1 3.75Å; F514-F539 HydrophobicContact CG-CE1 4.45Å; F514-F539 HydrophobicContact CG-CG 4.09Å; F514-I633 CarbonylContact O-C 3.51Å; F514-I633 WeakPolarHBondContact O-CA 3.48Å; F514-I634 HydrophobicContact CB-CB 4.32Å; F514-I634 HydrophobicContact CD2-CB 4.47Å; F514-I634 HydrophobicContact CD2-CG2 4.36Å; F514-I634 PolarHBondContact N-O 3.5Å; F514-I634 PolarHBondContact O-N 2.9Å; F514-L636 HydrophobicContact CE2-CB 4.06Å; F514-L636 HydrophobicContact CE2-CD2 3.94Å
515R87.9Confident78Confident203 Ų20371.2 Ų71.277%0.76637%0.372SS*.EExtended strand (participates in β ladder)trans-91.4133.7172.9-65.2-177.2-179.9-101.80.1108.7I633R515-I633 HydrophobicContact CG-CG1 4.36Å
516G87.9Confident80.5Confident17 Ų1765.3 Ų65.318%0.17533%0.331CS..EExtended strand (participates in β ladder)trans-143.1173.8178.800000112.4F632G516-F632 PolarHBondContact N-O 2.69Å; G516-F632 PolarHBondContact O-N 2.8Å; G516-F632 VanDerWaalsContact O-O 3.13Å
517S93.7Very high83.1Confident42 Ų4262.1 Ų62.129%0.29431%0.314SS..EExtended strand (participates in β ladder)trans-147134.8172.3530000110.2T523 A630S517-T523 PolarHBondContact O-OG1 3.12Å; S517-A630 CarbonylContact C-O 3.5Å; S517-A630 VanDerWaalsContact CA-O 3.27Å; S517-A630 WeakPolarHBondContact CA-O 3.39Å
518W96.6Very high85Confident3 Ų365.3 Ų65.31%0.01132%0.316CS..EExtended strand (participates in β ladder)trans-80125.4161-57.7-67.4000107.7A524 L559 Q561 I571 P621 T623 C628 S629 A630 F632W518-A524 HydrophobicContact CB-CB 3.93Å; W518-L559 HydrophobicContact CH2-CD1 4.26Å; W518-L559 HydrophobicContact CH2-CD2 4.07Å; W518-L559 HydrophobicContact CH2-CG 4.46Å; W518-L559 HydrophobicContact CZ2-CD1 4.41Å; W518-L559 HydrophobicContact CZ2-CD2 4.09Å; W518-Q561 HydrophobicContact CZ3-CB 4.39Å; W518-I571 HydrophobicContact CH2-CB 4.25Å; W518-I571 HydrophobicContact CH2-CG2 3.56Å; W518-I571 HydrophobicContact CZ3-CG2 3.85Å; W518-P621 HydrophobicContact CZ2-CB 3.96Å; W518-P621 PolarHBondContact NE1-O 2.81Å; W518-T623 HydrophobicContact CD2-CG2 3.84Å; W518-T623 HydrophobicContact CE3-CG2 3.65Å; W518-T623 HydrophobicContact CG-CG2 4.4Å; W518-T623 HydrophobicContact CH2-CG2 4.32Å; W518-T623 HydrophobicContact CZ2-CG2 4.46Å; W518-T623 HydrophobicContact CZ3-CG2 3.91Å; W518-C628 VanDerWaalsContact CB-O 3.23Å; W518-C628 WeakPolarHBondContact CB-O 3.47Å; W518-S629 VanDerWaalsContact O-CA 3.25Å; W518-S629 WeakPolarHBondContact O-CA 3.2Å; W518-A630 HydrophobicContact CE3-CB 3.99Å; W518-A630 HydrophobicContact CZ3-CB 4.33Å; W518-A630 PolarHBondContact N-O 2.92Å; W518-A630 PolarHBondContact O-N 3.22Å; W518-A630 VanDerWaalsContact O-N 3.13Å; W518-F632 AromaticContact CD1-CE1 3.98Å; W518-F632 AromaticContact CD2-CD1 3.54Å; W518-F632 HydrophobicContact CD2-CD1 3.54Å; W518-F632 AromaticContact CD2-CE1 3.68Å; W518-F632 HydrophobicContact CD2-CE1 3.68Å; W518-F632 AromaticContact CE2-CD1 3.6Å; W518-F632 AromaticContact CE2-CE1 3.54Å; W518-F632 AromaticContact CE3-CD1 3.6Å; W518-F632 HydrophobicContact CE3-CD1 3.6Å; W518-F632 HydrophobicContact CE3-CE1 4.23Å; W518-F632 HydrophobicContact CE3-CG 4.49Å; W518-F632 HydrophobicContact CG-CD1 4.23Å; W518-F632 AromaticContact CG-CE1 3.98Å; W518-F632 HydrophobicContact CG-CE1 3.98Å; W518-F632 HydrophobicContact CH2-CB 4.06Å; W518-F632 AromaticContact CH2-CD1 3.81Å; W518-F632 HydrophobicContact CH2-CD1 3.81Å; W518-F632 HydrophobicContact CH2-CG 4.06Å; W518-F632 AromaticContact CZ2-CD1 3.76Å; W518-F632 HydrophobicContact CZ2-CD1 3.76Å; W518-F632 HydrophobicContact CZ2-CE1 4.01Å; W518-F632 HydrophobicContact CZ2-CG 4.22Å; W518-F632 HydrophobicContact CZ3-CB 4.02Å; W518-F632 AromaticContact CZ3-CD1 3.74Å; W518-F632 HydrophobicContact CZ3-CD1 3.74Å; W518-F632 HydrophobicContact CZ3-CG 4.2Å; W518-F632 AromaticContact NE1-CE1 3.7Å
519I94.6Very high86.5Confident63 Ų6364.8 Ų64.832%0.32332%0.318SS..  trans-123.7123.6-179.3-56.3171.7000106.7G521 R522 T523 A524I519-G521 PolarHBondContact O-N 2.95Å; I519-R522 HydrophobicContact CB-CB 4.28Å; I519-R522 HydrophobicContact CG2-CB 4.28Å; I519-R522 PolarHBondContact O-N 3.13Å; I519-R522 VanDerWaalsContact O-N 3.08Å; I519-T523 PolarHBondContact N-OG1 3.44Å; I519-T523 PolarHBondContact O-N 2.92Å; I519-A524 WeakPolarHBondContact O-CB 3.35Å; I519-A524 PolarHBondContact O-N 3.31Å
520E93.8Very high87.5Confident131 Ų13165.2 Ų65.261%0.61232%0.322SS*.THydrogen-bonded Turntrans-45.9133.6174.4177.3170.7-172.900112.3R522 D627 S629E520-R522 PolarHBondContact O-N 3.2Å; E520-D627 HydrophobicContact CB-CB 4.48Å; E520-D627 HydrophobicContact CG-CB 3.94Å; E520-S629 PolarHBondContact N-OG 2.95Å
521G86.4Confident88.3Confident56 Ų5668.4 Ų68.458%0.57735%0.348SS*.THydrogen-bonded Turntrans65.92.9-179.500000116.1I519 D627I519-G521 PolarHBondContact O-N 2.95Å; G521-D627 PolarHBondContact N-OD1 3.07Å
522R89.9Confident88.9Confident177 Ų17767 Ų6767%0.66834%0.34SS*.THydrogen-bonded Turntrans-130.7-57.9-176.3-66.5-174.464.7-163.3-1.3114I519 E520I519-R522 HydrophobicContact CB-CB 4.28Å; I519-R522 HydrophobicContact CG2-CB 4.28Å; I519-R522 PolarHBondContact O-N 3.13Å; I519-R522 VanDerWaalsContact O-N 3.08Å; E520-R522 PolarHBondContact O-N 3.2Å
523T92.8Very high89.9Confident32 Ų3265.3 Ų65.320%0.19633%0.328CS..THydrogen-bonded Turntrans-129.2-2.2-17462.20000113.2S517 I519 G525 Q535 N536 P537S517-T523 PolarHBondContact O-OG1 3.12Å; I519-T523 PolarHBondContact N-OG1 3.44Å; I519-T523 PolarHBondContact O-N 2.92Å; T523-G525 VanDerWaalsContact C-N 3.35Å; T523-G525 PolarHBondContact O-N 3.08Å; T523-Q535 WeakPolarHBondContact CA-O 3.45Å; T523-N536 WeakPolarHBondContact O-CA 3.45Å; T523-N536 PolarHBondContact O-OD1 3.1Å; T523-P537 WeakPolarHBondContact O-CD 3.27Å
524A93.6Very high90.3Very high2 Ų264.5 Ų64.52%0.01732%0.321CS..  trans-88.269.2174.500000110.8W518 I519 G526 P626 D627W518-A524 HydrophobicContact CB-CB 3.93Å; I519-A524 WeakPolarHBondContact O-CB 3.35Å; I519-A524 PolarHBondContact O-N 3.31Å; A524-G526 VanDerWaalsContact C-N 3.3Å; A524-G526 PolarHBondContact O-N 3.39Å; A524-P626 CarbonylContact O-C 3.6Å; A524-P626 WeakPolarHBondContact O-CA 3.44Å; A524-D627 PolarHBondContact O-N 2.93Å
525G92.6Very high90.9Very high0 Ų066.9 Ų66.90%033%0.333CS..  trans-75.6-10.1-172.500000115.8T523 S532 Y533 N536T523-G525 VanDerWaalsContact C-N 3.35Å; T523-G525 PolarHBondContact O-N 3.08Å; G525-S532 WeakPolarHBondContact CA-O 3.46Å; G525-S532 CarbonylContact O-C 3.54Å; G525-S532 VanDerWaalsContact O-C 3.27Å; G525-S532 PolarHBondContact O-OG 3.47Å; G525-Y533 PolarHBondContact O-N 2.84Å; G525-N536 PolarHBondContact N-OD1 3.15Å; G525-N536 VanDerWaalsContact N-OD1 3.12Å
526G89.9Confident91.2Very high0 Ų057.4 Ų57.40%030%0.297CS..  trans74.4-173.5-175.800000113.2A524 Y533 N536 S622 T623A524-G526 VanDerWaalsContact C-N 3.3Å; A524-G526 PolarHBondContact O-N 3.39Å; G526-Y533 VanDerWaalsContact O-CD2 3.28Å; G526-Y533 WeakPolarHBondContact O-CD2 3.46Å; G526-N536 PolarHBondContact O-ND2 2.96Å; G526-S622 WeakPolarHBondContact O-CB 3.44Å; G526-T623 CarbonylContact C-O 3.27Å; G526-T623 WeakPolarHBondContact CA-O 3.15Å
527S92.7Very high91.4Very high3 Ų357.6 Ų57.62%0.02130%0.296CS..SBendtrans-73.4171.7179.662.30000113.1N529 F530 T623 Y624S527-N529 PolarHBondContact O-N 3.4Å; S527-F530 PolarHBondContact O-N 2.79Å; S527-F530 WeakPolarHBondContact OG-CD2 3.44Å; S527-F530 WeakPolarHBondContact OG-CE2 3.32Å; S527-T623 PolarHBondContact N-O 2.93Å; S527-Y624 WeakPolarHBondContact CB-O 3.37Å; S527-Y624 PolarHBondContact N-O 3.44Å; S527-Y624 PolarHBondContact OG-O 2.69Å
528R90.4Very high91.2Very high96 Ų9657.9 Ų57.936%0.36230%0.297SS..THydrogen-bonded Turntrans-56.1-15.8-179.9-76.1-17875.7-147.47.9114.5F530 Y533 Y576 K591 D592R528-F530 PolarHBondContact O-N 2.79Å; R528-Y533 HydrophobicContact CB-CD2 4.37Å; R528-Y533 HydrophobicContact CB-CE2 4.47Å; R528-Y533 HydrophobicContact CB-CG 4.5Å; R528-Y533 HydrophobicContact CG-CD1 4.02Å; R528-Y533 HydrophobicContact CG-CD2 3.95Å; R528-Y533 HydrophobicContact CG-CE1 3.7Å; R528-Y533 HydrophobicContact CG-CE2 3.64Å; R528-Y533 HydrophobicContact CG-CG 4.14Å; R528-Y533 VanDerWaalsContact N-CD2 3.32Å; R528-Y576 VanDerWaalsContact CD-OH 3.29Å; R528-Y576 WeakPolarHBondContact CD-OH 3.34Å; R528-Y576 PolarHBondContact NE-OH 3.33Å; R528-K591 PolarHBondContact NH2-O 2.82Å; R528-K591 VanDerWaalsContact NH2-O 3.1Å; R528-D592 IonicContact NH2-OD1 3.13Å; R528-D592 PolarHBondContact NH2-OD1 3.26Å; R528-D592 VanDerWaalsContact NH2-OD1 3.13Å
529N86.7Confident90.8Very high126 Ų12659.1 Ų59.167%0.67430%0.303SS*.THydrogen-bonded Turntrans-73.4-10177.1-62.6-22.2000113.1S527S527-N529 PolarHBondContact O-N 3.4Å
530F89.5Confident90.4Very high68 Ų6860.5 Ų60.530%0.29832%0.315SS..SBendtrans-109.3139.3-177.8-62.9-85.7000111.5S527 R528 S532 Y533 Y624 P626S527-F530 PolarHBondContact O-N 2.79Å; S527-F530 WeakPolarHBondContact OG-CD2 3.44Å; S527-F530 WeakPolarHBondContact OG-CE2 3.32Å; R528-F530 PolarHBondContact O-N 2.79Å; F530-S532 PolarHBondContact O-N 3.4Å; F530-Y533 WeakPolarHBondContact O-CB 3.22Å; F530-Y533 PolarHBondContact O-N 2.89Å; F530-Y624 WeakPolarHBondContact CE2-O 3.24Å; F530-P626 HydrophobicContact CD1-CG 3.99Å; F530-P626 HydrophobicContact CE1-CG 4.16Å; F530-P626 HydrophobicContact CG-CG 4.35Å
531P87.6Confident89.9Confident131 Ų13155 Ų5585%0.85129%0.29SS*.G310 helixtrans-59.3-28.1176.7-24.934.1000113.9Y533P531-Y533 PolarHBondContact O-N 3.41Å
532S90.1Very high89.7Confident29 Ų2953.9 Ų53.920%0.20328%0.275CS..G310 helixtrans-74.2-2.8176.9450000113.8G525 F530 W534 Q535G525-S532 WeakPolarHBondContact CA-O 3.46Å; G525-S532 CarbonylContact O-C 3.54Å; G525-S532 VanDerWaalsContact O-C 3.27Å; G525-S532 PolarHBondContact O-OG 3.47Å; F530-S532 PolarHBondContact O-N 3.4Å; S532-W534 PolarHBondContact O-N 3.46Å; S532-Q535 VanDerWaalsContact O-CB 3.22Å; S532-Q535 WeakPolarHBondContact O-CB 3.45Å; S532-Q535 WeakPolarHBondContact O-CG 3.41Å; S532-Q535 PolarHBondContact O-N 3.01Å
533Y92.3Very high89.3Confident5 Ų545.9 Ų45.92%0.0225%0.246CC..G310 helixtrans-49-39.7-176.1174.6-105000113.9G525 G526 R528 F530 P531 Q535 N536 H574 Y576 V620G525-Y533 PolarHBondContact O-N 2.84Å; G526-Y533 VanDerWaalsContact O-CD2 3.28Å; G526-Y533 WeakPolarHBondContact O-CD2 3.46Å; R528-Y533 HydrophobicContact CB-CD2 4.37Å; R528-Y533 HydrophobicContact CB-CE2 4.47Å; R528-Y533 HydrophobicContact CB-CG 4.5Å; R528-Y533 HydrophobicContact CG-CD1 4.02Å; R528-Y533 HydrophobicContact CG-CD2 3.95Å; R528-Y533 HydrophobicContact CG-CE1 3.7Å; R528-Y533 HydrophobicContact CG-CE2 3.64Å; R528-Y533 HydrophobicContact CG-CG 4.14Å; R528-Y533 VanDerWaalsContact N-CD2 3.32Å; F530-Y533 WeakPolarHBondContact O-CB 3.22Å; F530-Y533 PolarHBondContact O-N 2.89Å; P531-Y533 PolarHBondContact O-N 3.41Å; Y533-Q535 PolarHBondContact O-N 3.34Å; Y533-N536 WeakPolarHBondContact O-CB 3.46Å; Y533-N536 PolarHBondContact O-N 3.19Å; Y533-N536 VanDerWaalsContact O-N 3.11Å; Y533-N536 PolarHBondContact O-ND2 2.78Å; Y533-H574 AromaticContact CZ-CD2 3.93Å; Y533-H574 WeakPolarHBondContact OH-CB 3.48Å; Y533-H574 PolarHBondContact OH-CD2 2.94Å; Y533-Y576 HydrophobicContact CE1-CE2 4.21Å; Y533-Y576 VanDerWaalsContact CE1-OH 3.25Å; Y533-Y576 WeakPolarHBondContact CE1-OH 3.43Å; Y533-Y576 WeakPolarHBondContact OH-CE2 3.35Å; Y533-Y576 PolarHBondContact OH-OH 3.03Å; Y533-V620 HydrophobicContact CE1-CG1 4.27Å; Y533-V620 HydrophobicContact CE2-CG1 4.24Å; Y533-V620 WeakPolarHBondContact OH-CB 3.27Å
534W90Very high88Confident119 Ų11949.1 Ų49.145%0.45127%0.268SS..G310 helixtrans-75.2-4.4-177.3-62.9114.1000114.7S532 N536 Y576 K589S532-W534 PolarHBondContact O-N 3.46Å; W534-N536 VanDerWaalsContact C-N 3.28Å; W534-Y576 HydrophobicContact CH2-CD1 4.14Å; W534-Y576 HydrophobicContact CH2-CD2 4.32Å; W534-Y576 AromaticContact CH2-CE1 3.65Å; W534-Y576 HydrophobicContact CH2-CE1 3.65Å; W534-Y576 AromaticContact CH2-CE2 3.85Å; W534-Y576 HydrophobicContact CH2-CE2 3.85Å; W534-Y576 HydrophobicContact CH2-CG 4.44Å; W534-Y576 AromaticContact CH2-CZ 3.49Å; W534-Y576 VanDerWaalsContact CH2-CZ 3.49Å; W534-Y576 HydrophobicContact CZ2-CE1 4.49Å; W534-Y576 HydrophobicContact CZ3-CD2 4.23Å; W534-Y576 HydrophobicContact CZ3-CE1 4.46Å; W534-Y576 AromaticContact CZ3-CE2 3.84Å; W534-Y576 HydrophobicContact CZ3-CE2 3.84Å; W534-Y576 AromaticContact CZ3-CZ 3.98Å; W534-K589 HydrophobicContact CE3-CD 3.98Å; W534-K589 HydrophobicContact CH2-CB 4.49Å; W534-K589 HydrophobicContact CH2-CD 4.01Å; W534-K589 HydrophobicContact CZ3-CD 3.47Å; W534-K589 VanDerWaalsContact CZ3-CD 3.47Å
535Q90.3Very high86.4Confident102 Ų10252.1 Ų52.148%0.47728%0.284SS..G310 helixtrans-78.5-15.3169.6-57.8175.312.800111.9T523 S532 Y533T523-Q535 WeakPolarHBondContact CA-O 3.45Å; S532-Q535 VanDerWaalsContact O-CB 3.22Å; S532-Q535 WeakPolarHBondContact O-CB 3.45Å; S532-Q535 WeakPolarHBondContact O-CG 3.41Å; S532-Q535 PolarHBondContact O-N 3.01Å; Y533-Q535 PolarHBondContact O-N 3.34Å
536N93.7Very high84.3Confident3 Ų360.5 Ų60.52%0.01632%0.323CS..SBendtrans-59147.4175-73.7-67.1000111.5T523 G525 G526 Y533 W534 C538 V620 P621T523-N536 WeakPolarHBondContact O-CA 3.45Å; T523-N536 PolarHBondContact O-OD1 3.1Å; G525-N536 PolarHBondContact N-OD1 3.15Å; G525-N536 VanDerWaalsContact N-OD1 3.12Å; G526-N536 PolarHBondContact O-ND2 2.96Å; Y533-N536 WeakPolarHBondContact O-CB 3.46Å; Y533-N536 PolarHBondContact O-N 3.19Å; Y533-N536 VanDerWaalsContact O-N 3.11Å; Y533-N536 PolarHBondContact O-ND2 2.78Å; W534-N536 VanDerWaalsContact C-N 3.28Å; N536-C538 PolarHBondContact O-N 3.12Å; N536-C538 PolarHBondContact O-SG 3.38Å; N536-V620 HydrophobicContact CB-CG1 3.67Å; N536-P621 WeakPolarHBondContact CB-O 3.45Å
537P92.9Very high82.1Confident22 Ų2266.2 Ų66.214%0.14336%0.36CS..  trans-53.9140.2176.2-26.437000111.3T523 F539 P621 F632T523-P537 WeakPolarHBondContact O-CD 3.27Å; P537-F539 HydrophobicContact CB-CE2 3.61Å; P537-F539 HydrophobicContact CB-CZ 3.86Å; P537-P621 VanDerWaalsContact O-CD 3.32Å; P537-P621 WeakPolarHBondContact O-CD 3.47Å; P537-F632 HydrophobicContact CB-CZ 4.07Å; P537-F632 HydrophobicContact CG-CE1 4.17Å; P537-F632 HydrophobicContact CG-CZ 3.9Å
538C89.8Confident79.7Confident47 Ų4769.9 Ų69.932%0.31839%0.391SS..  trans-120.1127.3178.2-65.30000109N536 K589 T618N536-C538 PolarHBondContact O-N 3.12Å; N536-C538 PolarHBondContact O-SG 3.38Å; C538-K589 PolarHBondContact SG-NZ 3.26Å; C538-T618 HydrophobicContact CB-CG2 4.01Å
539F87.2Confident77.6Confident30 Ų3074 Ų7413%0.13242%0.419CS..EExtended strand (participates in β ladder)trans-116.6107.8-180-58.4-85000110.2F514 P537 T618 V619 P621 F632 I634F514-F539 HydrophobicContact CB-CD1 3.5Å; F514-F539 VanDerWaalsContact CB-CD1 3.5Å; F514-F539 HydrophobicContact CB-CE1 3.73Å; F514-F539 HydrophobicContact CB-CG 3.96Å; F514-F539 HydrophobicContact CB-CZ 4.38Å; F514-F539 HydrophobicContact CD1-CB 4.34Å; F514-F539 AromaticContact CD1-CD1 3.78Å; F514-F539 HydrophobicContact CD1-CD1 3.78Å; F514-F539 HydrophobicContact CD1-CG 4.4Å; F514-F539 HydrophobicContact CD2-CB 4.32Å; F514-F539 HydrophobicContact CG-CB 4.14Å; F514-F539 AromaticContact CG-CD1 3.75Å; F514-F539 HydrophobicContact CG-CD1 3.75Å; F514-F539 HydrophobicContact CG-CE1 4.45Å; F514-F539 HydrophobicContact CG-CG 4.09Å; P537-F539 HydrophobicContact CB-CE2 3.61Å; P537-F539 HydrophobicContact CB-CZ 3.86Å; F539-T618 WeakPolarHBondContact O-CA 2.85Å; F539-V619 HydrophobicContact CB-CG1 3.76Å; F539-V619 HydrophobicContact CD2-CG1 4.43Å; F539-V619 PolarHBondContact N-O 2.82Å; F539-V619 PolarHBondContact O-N 3.32Å; F539-P621 HydrophobicContact CD2-CG 4.2Å; F539-P621 HydrophobicContact CE2-CG 3.85Å; F539-F632 AromaticContact CE2-CE2 3.71Å; F539-F632 HydrophobicContact CE2-CE2 3.71Å; F539-F632 AromaticContact CE2-CZ 3.86Å; F539-F632 HydrophobicContact CE2-CZ 3.86Å; F539-F632 HydrophobicContact CZ-CE2 4Å; F539-F632 HydrophobicContact CZ-CZ 4.13Å; F539-I634 HydrophobicContact CD2-CD1 3.44Å; F539-I634 VanDerWaalsContact CD2-CD1 3.44Å; F539-I634 HydrophobicContact CE2-CD1 3.71Å; F539-I634 HydrophobicContact CG-CD1 4.27Å
540P86.1Confident75.6Confident91 Ų9172.2 Ų72.259%0.59141%0.413SS*.EExtended strand (participates in β ladder)trans-74.3144.8179.229.9-33.5000111.6Y617 T618P540-Y617 CarbonylContact C-O 3.48Å; P540-Y617 VanDerWaalsContact CA-O 3.26Å; P540-Y617 WeakPolarHBondContact CA-O 3.41Å; P540-T618 WeakPolarHBondContact CA-OG1 3.24Å
541F84Confident73.6Confident17 Ų1775.4 Ų75.48%0.07544%0.443CS..EExtended strand (participates in β ladder)trans-147.8163.3171.970.8-85.3000111.3V543 V555 I557 V575 L612 Y617 V619 L636F541-V543 HydrophobicContact CD2-CG2 4.34Å; F541-V543 HydrophobicContact CE2-CG2 4.02Å; F541-V555 HydrophobicContact CE2-CG1 4.23Å; F541-V555 HydrophobicContact CE2-CG2 4.42Å; F541-V555 HydrophobicContact CZ-CG1 4.42Å; F541-I557 HydrophobicContact CE1-CD1 4.46Å; F541-I557 HydrophobicContact CZ-CD1 4.39Å; F541-V575 HydrophobicContact CE1-CG1 3.96Å; F541-V575 HydrophobicContact CZ-CG1 3.86Å; F541-L612 HydrophobicContact CE2-CD1 3.99Å; F541-L612 HydrophobicContact CZ-CD1 3.77Å; F541-Y617 VanDerWaalsContact CE1-CB 3.47Å; F541-Y617 HydrophobicContact CE2-CD2 4.06Å; F541-Y617 HydrophobicContact CE2-CG 4.17Å; F541-Y617 HydrophobicContact CZ-CD2 4.37Å; F541-Y617 HydrophobicContact CZ-CG 4.01Å; F541-Y617 PolarHBondContact N-O 3.15Å; F541-Y617 PolarHBondContact O-N 3.2Å; F541-Y617 VanDerWaalsContact O-O 3.1Å; F541-V619 HydrophobicContact CE1-CB 4.44Å; F541-L636 HydrophobicContact CB-CD2 3.27Å; F541-L636 HydrophobicContact CD1-CD1 4.45Å; F541-L636 HydrophobicContact CD1-CD2 3.95Å; F541-L636 HydrophobicContact CD2-CD1 4.14Å; F541-L636 HydrophobicContact CD2-CD2 3.75Å; F541-L636 HydrophobicContact CE1-CD1 4.43Å; F541-L636 HydrophobicContact CE2-CD1 4.12Å; F541-L636 HydrophobicContact CG-CD1 4.3Å; F541-L636 HydrophobicContact CG-CD2 3.4Å; F541-L636 VanDerWaalsContact CG-CD2 3.4Å; F541-L636 HydrophobicContact CZ-CD1 4.26Å
542A81.4Confident72.7Confident31 Ų3171 Ų7126%0.25642%0.421SS..EExtended strand (participates in β ladder)trans-125.5146.9178.900000111.4G615 R638A542-G615 WeakPolarHBondContact CA-O 3.46Å; A542-R638 PolarHBondContact O-NH1 3Å
543V81.3Confident72Confident10 Ų1072.2 Ų72.26%0.06143%0.428CS..EExtended strand (participates in β ladder)trans-113.7120.1171.3-1780000107.1F541 V555 L612 P614 G615 Y617F541-V543 HydrophobicContact CD2-CG2 4.34Å; F541-V543 HydrophobicContact CE2-CG2 4.02Å; V543-V555 HydrophobicContact CG2-CG2 3.86Å; V543-L612 HydrophobicContact CG2-CB 4.35Å; V543-P614 CarbonylContact O-C 3.56Å; V543-P614 VanDerWaalsContact O-CA 3.28Å; V543-P614 WeakPolarHBondContact O-CA 3.48Å; V543-G615 PolarHBondContact N-O 2.75Å; V543-G615 PolarHBondContact O-N 2.83Å; V543-Y617 HydrophobicContact CB-CE2 4.2Å; V543-Y617 HydrophobicContact CG2-CD2 3.94Å; V543-Y617 HydrophobicContact CG2-CE2 3.88Å
544C65.3Low71.5Confident100 Ų10073.6 Ų73.668%0.67644%0.436SS*.  trans-110.61.3-164.3-59.30000115.4
545D60.4Low71.3Confident64 Ų6468 Ų6834%0.34241%0.414SS..  trans-95121.3-166.3-69.2-18.1000113.8P614D545-P614 WeakPolarHBondContact O-CG 3.46Å
546E48.9Very low71.3Confident177 Ų17767 Ų6783%0.82741%0.406SS*.  trans-61.9145.2168.2-80.5-148.5165.800112.3A548E546-A548 PolarHBondContact O-N 3.3Å
547P43.9Very low71.2Confident120 Ų12066.8 Ų66.878%0.77941%0.405SS*.  trans-76.882.5-170.432.1-34.5000111.6L549P547-L549 PolarHBondContact O-N 2.83Å
548A41.2Very low71.2Confident79 Ų7967.6 Ų67.665%0.65341%0.41SS*.  trans-88.6100.6160.400000109.5E546 T550E546-A548 PolarHBondContact O-N 3.3Å; A548-T550 VanDerWaalsContact C-N 3.28Å; A548-T550 PolarHBondContact O-N 2.93Å; A548-T550 PolarHBondContact O-OG1 3.07Å
549L46.7Very low71.4Confident182 Ų18265.4 Ų65.495%0.95340%0.395SS*.SBendtrans38.833.8153.6-122.591.4000119.4P547P547-L549 PolarHBondContact O-N 2.83Å
550T44.5Very low71.7Confident90 Ų9066.5 Ų66.555%0.55240%0.4SS*.  trans-12095.4170.446.30000110A548 G552A548-T550 VanDerWaalsContact C-N 3.28Å; A548-T550 PolarHBondContact O-N 2.93Å; A548-T550 PolarHBondContact O-OG1 3.07Å; T550-G552 PolarHBondContact O-N 2.78Å; T550-G552 VanDerWaalsContact O-N 3.13Å
551S48.5Very low72.1Confident134 Ų13462.1 Ų62.194%0.93737%0.372SS*.  trans-66.9102.8164.9167.80000108.3
552G67.8Low72.4Confident38 Ų3864.5 Ų64.539%0.39239%0.391SS..SBendtrans-179.2167.717800000114.9T550 N554T550-G552 PolarHBondContact O-N 2.78Å; T550-G552 VanDerWaalsContact O-N 3.13Å; G552-N554 PolarHBondContact O-N 3.31Å
553V76.5Confident72.6Confident56 Ų5665.7 Ų65.734%0.33939%0.388SS..  trans-58.1127.7173.4-179.80000109.2W509 V555 R556 A609 C610W509-V553 HydrophobicContact CH2-CB 4.47Å; W509-V553 HydrophobicContact CH2-CG1 3.93Å; W509-V553 WeakPolarHBondContact CH2-O 3.34Å; W509-V553 VanDerWaalsContact CZ2-O 3.24Å; W509-V553 WeakPolarHBondContact CZ2-O 3.3Å; V553-V555 WeakPolarHBondContact CG1-O 3.47Å; V553-R556 HydrophobicContact CG1-CG 4.11Å; V553-A609 HydrophobicContact CG1-CB 3.69Å; V553-A609 HydrophobicContact CG2-CB 4.27Å; V553-C610 WeakPolarHBondContact CG1-O 3.49Å
554N80.6Confident72.6Confident34 Ų3468.9 Ų68.918%0.18241%0.41CS..  trans-121.7-5.6177.770.7-8000113.8W509 G552 C610 A611 L612 R638 K639W509-N554 VanDerWaalsContact CH2-C 3.44Å; W509-N554 VanDerWaalsContact CZ3-C 3.41Å; W509-N554 WeakPolarHBondContact CZ3-O 3.45Å; G552-N554 PolarHBondContact O-N 3.31Å; N554-C610 PolarHBondContact N-O 3.21Å; N554-C610 VanDerWaalsContact N-O 3.14Å; N554-C610 PolarHBondContact OD1-O 3.23Å; N554-A611 VanDerWaalsContact OD1-CA 3.27Å; N554-A611 WeakPolarHBondContact OD1-CA 3.48Å; N554-L612 PolarHBondContact ND2-O 3.32Å; N554-L612 PolarHBondContact OD1-N 2.64Å; N554-R638 WeakPolarHBondContact O-CA 3.5Å; N554-K639 HydrophobicContact CB-CB 4.29Å; N554-K639 PolarHBondContact O-N 3.19Å
555V85.9Confident73.2Confident0 Ų069.6 Ų69.60%041%0.406CS..EExtended strand (participates in β ladder)trans-136.1132.7174.8177.20000110.3F541 V543 V553 I557 C610 L612 L636 A637F541-V555 HydrophobicContact CE2-CG1 4.23Å; F541-V555 HydrophobicContact CE2-CG2 4.42Å; F541-V555 HydrophobicContact CZ-CG1 4.42Å; V543-V555 HydrophobicContact CG2-CG2 3.86Å; V553-V555 WeakPolarHBondContact CG1-O 3.47Å; V555-I557 HydrophobicContact CG1-CD1 4.2Å; V555-I557 HydrophobicContact CG1-CG1 3.92Å; V555-C610 PolarHBondContact N-O 2.82Å; V555-C610 PolarHBondContact O-N 3.1Å; V555-C610 VanDerWaalsContact O-O 3.09Å; V555-L612 HydrophobicContact CB-CD1 4.28Å; V555-L612 HydrophobicContact CG1-CD1 4.29Å; V555-L612 HydrophobicContact CG2-CB 4.32Å; V555-L612 HydrophobicContact CG2-CD1 4.11Å; V555-L612 HydrophobicContact CG2-CG 4.37Å; V555-L636 HydrophobicContact CG1-CD1 3.68Å; V555-A637 CarbonylContact C-O 3.52Å; V555-A637 WeakPolarHBondContact CA-O 3.2Å
556R90.6Very high74Confident81 Ų8173 Ų7331%0.30643%0.43SS..EExtended strand (participates in β ladder)trans-125132.2170-61.4179.4-179176.42.6109.5W509 V553 L608 A609 L636 A637W509-R556 HydrophobicContact CH2-CG 4.09Å; W509-R556 HydrophobicContact CZ3-CB 4.48Å; W509-R556 HydrophobicContact CZ3-CG 3.92Å; V553-R556 HydrophobicContact CG1-CG 4.11Å; R556-L608 CarbonylContact C-O 3.59Å; R556-L608 WeakPolarHBondContact CA-O 3.29Å; R556-A609 HydrophobicContact CG-CB 4.13Å; R556-L636 CarbonylContact O-C 3.54Å; R556-L636 WeakPolarHBondContact O-CA 3.31Å; R556-A637 HydrophobicContact CB-CB 4.25Å; R556-A637 PolarHBondContact N-O 3Å; R556-A637 PolarHBondContact O-N 3.3Å
557I91.8Very high75.8Confident0 Ų068.4 Ų68.40%041%0.411CS..EExtended strand (participates in β ladder)trans-126.2126.3-179.7-54.8178.6000107.9F541 V555 F573 V575 S607 L608 V619 I634 S635 L636F541-I557 HydrophobicContact CE1-CD1 4.46Å; F541-I557 HydrophobicContact CZ-CD1 4.39Å; V555-I557 HydrophobicContact CG1-CD1 4.2Å; V555-I557 HydrophobicContact CG1-CG1 3.92Å; I557-F573 HydrophobicContact CB-CE1 4.49Å; I557-F573 HydrophobicContact CB-CE2 3.68Å; I557-F573 HydrophobicContact CB-CZ 3.58Å; I557-F573 HydrophobicContact CD1-CE2 4.11Å; I557-F573 HydrophobicContact CG1-CE2 4.45Å; I557-F573 HydrophobicContact CG2-CD2 4.14Å; I557-F573 HydrophobicContact CG2-CE1 4.07Å; I557-F573 HydrophobicContact CG2-CE2 3.59Å; I557-F573 HydrophobicContact CG2-CZ 3.54Å; I557-F573 WeakPolarHBondContact O-CZ 3.31Å; I557-V575 HydrophobicContact CD1-CG2 3.49Å; I557-V575 VanDerWaalsContact CD1-CG2 3.49Å; I557-S607 CarbonylContact O-C 3.48Å; I557-S607 VanDerWaalsContact O-CA 3.23Å; I557-S607 WeakPolarHBondContact O-CA 3.36Å; I557-L608 PolarHBondContact N-O 2.66Å; I557-L608 PolarHBondContact O-N 3.09Å; I557-V619 HydrophobicContact CD1-CB 4.46Å; I557-V619 HydrophobicContact CD1-CG2 4.36Å; I557-V619 HydrophobicContact CG2-CG2 4.22Å; I557-I634 HydrophobicContact CG2-CG2 3.84Å; I557-S635 CarbonylContact C-O 3.51Å; I557-S635 VanDerWaalsContact CA-O 3.3Å; I557-S635 WeakPolarHBondContact CA-O 3.11Å; I557-L636 HydrophobicContact CD1-CD1 4.02Å; I557-L636 HydrophobicContact CG1-CD1 3.58Å
558T93.8Very high78Confident39 Ų3964 Ų6424%0.23938%0.381CS..EExtended strand (participates in β ladder)trans-120.1127.7172.1-58.60000109D605 V606 S607 I634 S635T558-D605 HydrophobicContact CG2-CB 4.37Å; T558-V606 CarbonylContact C-O 3.51Å; T558-V606 WeakPolarHBondContact CA-O 3.11Å; T558-S607 WeakPolarHBondContact CB-OG 3.43Å; T558-S607 VanDerWaalsContact CG2-OG 3.25Å; T558-S607 WeakPolarHBondContact CG2-OG 3.27Å; T558-S607 PolarHBondContact OG1-OG 2.84Å; T558-I634 CarbonylContact O-C 3.51Å; T558-I634 VanDerWaalsContact O-CA 3.28Å; T558-I634 WeakPolarHBondContact O-CA 3.44Å; T558-S635 PolarHBondContact N-O 3.47Å; T558-S635 PolarHBondContact O-N 2.85Å
559L93.1Very high80.5Confident0 Ų061.5 Ų61.50%036%0.356CS..EExtended strand (participates in β ladder)trans-105.9118.8172.2173.164.7000108.8W518 I571 F573 D605 V606 P621 F632 I634W518-L559 HydrophobicContact CH2-CD1 4.26Å; W518-L559 HydrophobicContact CH2-CD2 4.07Å; W518-L559 HydrophobicContact CH2-CG 4.46Å; W518-L559 HydrophobicContact CZ2-CD1 4.41Å; W518-L559 HydrophobicContact CZ2-CD2 4.09Å; L559-I571 HydrophobicContact CD2-CB 4.16Å; L559-I571 HydrophobicContact CD2-CD1 4.41Å; L559-I571 HydrophobicContact CG-CD1 4.25Å; L559-F573 HydrophobicContact CB-CD1 3.76Å; L559-F573 HydrophobicContact CB-CE1 4.13Å; L559-F573 HydrophobicContact CD2-CB 4.45Å; L559-F573 HydrophobicContact CD2-CD1 4.21Å; L559-D605 WeakPolarHBondContact O-CA 3.14Å; L559-V606 HydrophobicContact CB-CG2 3.87Å; L559-V606 HydrophobicContact CD2-CG2 4.22Å; L559-V606 HydrophobicContact CG-CG2 4.42Å; L559-V606 PolarHBondContact N-O 3.38Å; L559-V606 PolarHBondContact O-N 3.07Å; L559-P621 HydrophobicContact CD1-CB 3.72Å; L559-P621 HydrophobicContact CD2-CB 3.78Å; L559-P621 HydrophobicContact CG-CB 4.38Å; L559-F632 HydrophobicContact CD1-CB 3.92Å; L559-F632 HydrophobicContact CD1-CD2 3.54Å; L559-F632 HydrophobicContact CD1-CE2 4.28Å; L559-F632 HydrophobicContact CD1-CG 3.88Å; L559-I634 HydrophobicContact CD1-CG1 3.78Å
560H93.9Very high82.7Confident53 Ų5353.6 Ų53.625%0.24532%0.315CS..EExtended strand (participates in β ladder)trans-111123.4178.8-179.181.4000110.2Q604 D605 F632 I633H560-Q604 WeakPolarHBondContact CA-O 3.49Å; H560-D605 WeakPolarHBondContact CA-OD1 3.44Å; H560-D605 WeakPolarHBondContact CB-OD1 3.48Å; H560-D605 IonicContact CE1-OD2 3.3Å; H560-D605 IonicContact CG-OD1 3.99Å; H560-D605 VanDerWaalsContact CG-OD1 3.25Å; H560-D605 IonicContact ND1-OD1 2.66Å; H560-D605 PolarHBondContact ND1-OD1 2.68Å; H560-D605 IonicContact ND1-OD2 3.69Å; H560-D605 PolarHBondContact ND1-OD2 2.83Å; H560-F632 CarbonylContact O-C 3.58Å; H560-F632 WeakPolarHBondContact O-CA 3.5Å; H560-F632 WeakPolarHBondContact O-CB 3.4Å; H560-I633 HydrophobicContact CB-CB 4.44Å; H560-I633 PolarHBondContact N-O 3.3Å; H560-I633 PolarHBondContact O-N 2.77Å
561Q94.4Very high85.1Confident0 Ų049.3 Ų49.30%029%0.289CS..EExtended strand (participates in β ladder)trans-93.7136.9171.568.9-179.8-55.800111.4W518 R563 L568 H569 I571 T603 Q604W518-Q561 HydrophobicContact CZ3-CB 4.39Å; Q561-R563 PolarHBondContact O-N 2.73Å; Q561-L568 HydrophobicContact CG-CD2 4.09Å; Q561-H569 PolarHBondContact NE2-O 3.43Å; Q561-I571 HydrophobicContact CB-CD1 4.14Å; Q561-I571 HydrophobicContact CB-CG2 4.37Å; Q561-I571 HydrophobicContact CG-CD1 4.04Å; Q561-T603 PolarHBondContact NE2-O 2.71Å; Q561-Q604 PolarHBondContact N-O 3.06Å
562S90.1Very high87.3Confident66 Ų6642.9 Ų42.946%0.46224%0.244SC..  trans-91.670.1178.2-58.20000110.9K631S562-K631 PolarHBondContact N-O 3.03Å
563R86.5Confident88.6Confident56 Ų5641.1 Ų41.121%0.21123%0.226CC..SBendtrans-129.8153.3174.5-67.8-169.976.8102.6-1.2110.5Q561 D567 L568 H569 Q604 S629 A630Q561-R563 PolarHBondContact O-N 2.73Å; R563-D567 WeakPolarHBondContact CD-O 3.43Å; R563-D567 IonicContact CZ-OD2 3.57Å; R563-D567 PolarHBondContact NE-O 2.81Å; R563-D567 IonicContact NE-OD2 3.8Å; R563-D567 IonicContact NH2-OD1 3.02Å; R563-D567 PolarHBondContact NH2-OD1 2.91Å; R563-D567 IonicContact NH2-OD2 2.64Å; R563-D567 PolarHBondContact NH2-OD2 3.16Å; R563-L568 HydrophobicContact CB-CD2 4.15Å; R563-H569 PolarHBondContact NH1-NE2 3.34Å; R563-Q604 PolarHBondContact O-NE2 3.05Å; R563-S629 PolarHBondContact NH1-O 3.04Å; R563-A630 HydrophobicContact CG-CB 3.96Å
564P81.3Confident89.5Confident78 Ų7839 Ų3951%0.50621%0.212SC..  trans-66.8149.817428.2-33.3000111.4T566 D567P564-T566 PolarHBondContact O-N 2.74Å; P564-D567 HydrophobicContact CG-CB 4.27Å; P564-D567 CarbonylContact O-C 3.6Å; P564-D567 PolarHBondContact O-N 2.82Å
565D76.7Confident90.1Very high114 Ų11437.3 Ų37.361%0.6120%0.203SC*.THydrogen-bonded Turntrans-60.3-20.6-173.9-61.7-11.5000113.9D567 Q604D565-D567 VanDerWaalsContact C-N 3.33Å; D565-Q604 PolarHBondContact OD1-NE2 2.7Å
566T76.9Confident90.3Very high137 Ų13737.3 Ų37.384%0.8420%0.203SC*.THydrogen-bonded Turntrans-82.4-6177.756.10000114.1P564P564-T566 PolarHBondContact O-N 2.74Å
567D87.4Confident90.1Very high79 Ų7936.7 Ų36.742%0.42220%0.202SC..SBendtrans-150.758.7-171.5-17618.5000111.1R563 P564 D565R563-D567 WeakPolarHBondContact CD-O 3.43Å; R563-D567 IonicContact CZ-OD2 3.57Å; R563-D567 PolarHBondContact NE-O 2.81Å; R563-D567 IonicContact NE-OD2 3.8Å; R563-D567 IonicContact NH2-OD1 3.02Å; R563-D567 PolarHBondContact NH2-OD1 2.91Å; R563-D567 IonicContact NH2-OD2 2.64Å; R563-D567 PolarHBondContact NH2-OD2 3.16Å; P564-D567 HydrophobicContact CG-CB 4.27Å; P564-D567 CarbonylContact O-C 3.6Å; P564-D567 PolarHBondContact O-N 2.82Å; D565-D567 VanDerWaalsContact C-N 3.33Å
568L90.4Very high89.6Confident27 Ų2738.4 Ų38.414%0.14121%0.213CC..  trans-88.6144.5-179.6-64.2173.8000111.4Q561 R563 Y602 Q604Q561-L568 HydrophobicContact CG-CD2 4.09Å; R563-L568 HydrophobicContact CB-CD2 4.15Å; L568-Y602 VanDerWaalsContact O-CD1 3.22Å; L568-Y602 WeakPolarHBondContact O-CD1 3.2Å; L568-Y602 WeakPolarHBondContact O-CE1 3.43Å; L568-Q604 HydrophobicContact CD2-CB 4.48Å
569H92.9Very high88.4Confident28 Ų2840.7 Ų40.713%0.1322%0.223CC..  trans-85.2150.4164.6-68.1-44.6000110.7Q561 R563 I571 T623Q561-H569 PolarHBondContact NE2-O 3.43Å; R563-H569 PolarHBondContact NH1-NE2 3.34Å; H569-I571 HydrophobicContact CB-CG2 4.32Å; H569-I571 PolarHBondContact O-N 3.49Å; H569-T623 HydrophobicContact CB-CG2 3.98Å
570P93.3Very high86.5Confident15 Ų1549.4 Ų49.410%0.09726%0.264CS..  trans-69.2114.8166.729.8-34000109.3H600 C601 Y602 T623 Y624P570-H600 HydrophobicContact CB-CB 3.98Å; P570-C601 VanDerWaalsContact CA-O 3.3Å; P570-C601 WeakPolarHBondContact CA-O 3.24Å; P570-Y602 HydrophobicContact CB-CD2 4.32Å; P570-Y602 HydrophobicContact CB-CE1 4.43Å; P570-Y602 HydrophobicContact CB-CE2 4.15Å; P570-Y602 HydrophobicContact CG-CE1 4.21Å; P570-Y602 HydrophobicContact CG-CE2 4.39Å; P570-T623 CarbonylContact O-C 3.15Å; P570-T623 WeakPolarHBondContact O-CA 3.12Å; P570-Y624 VanDerWaalsContact CG-CB 3.46Å; P570-Y624 HydrophobicContact CG-CG 4.44Å; P570-Y624 PolarHBondContact O-N 3.44Å
571I95Very high84.1Confident0 Ų051.9 Ų51.90%028%0.282CS..EExtended strand (participates in β ladder)trans-115.7149.6-173.958.1167.5000112.4W518 L559 Q561 H569 H600 C601 V606 T623W518-I571 HydrophobicContact CH2-CB 4.25Å; W518-I571 HydrophobicContact CH2-CG2 3.56Å; W518-I571 HydrophobicContact CZ3-CG2 3.85Å; L559-I571 HydrophobicContact CD2-CB 4.16Å; L559-I571 HydrophobicContact CD2-CD1 4.41Å; L559-I571 HydrophobicContact CG-CD1 4.25Å; Q561-I571 HydrophobicContact CB-CD1 4.14Å; Q561-I571 HydrophobicContact CB-CG2 4.37Å; Q561-I571 HydrophobicContact CG-CD1 4.04Å; H569-I571 HydrophobicContact CB-CG2 4.32Å; H569-I571 PolarHBondContact O-N 3.49Å; I571-H600 VanDerWaalsContact C-CD2 3.46Å; I571-H600 WeakPolarHBondContact O-CA 3.35Å; I571-C601 PolarHBondContact N-O 2.78Å; I571-C601 PolarHBondContact O-N 3.19Å; I571-V606 HydrophobicContact CD1-CG1 4.47Å; I571-V606 HydrophobicContact CD1-CG2 4.16Å; I571-V606 HydrophobicContact CG1-CG1 4.07Å; I571-V606 HydrophobicContact CG1-CG2 4.14Å; I571-T623 HydrophobicContact CG2-CG2 4.41Å
572G93.9Very high81.5Confident0 Ų061.6 Ų61.60%033%0.328CS..EExtended strand (participates in β ladder)trans-166.2167.4-179.300000111.2C597 H600 S622G572-C597 WeakPolarHBondContact CA-O 3.48Å; G572-H600 PolarHBondContact N-CD2 3.04Å; G572-S622 PolarHBondContact N-O 3.32Å; G572-S622 PolarHBondContact O-N 3.34Å; G572-S622 PolarHBondContact O-OG 3.18Å
573F96.1Very high79Confident1 Ų163.1 Ų63.10%0.00434%0.338CS..EExtended strand (participates in β ladder)trans-148.5159179.163.5-96.5000113I557 L559 V575 C597 V606 L608 V619 V620 P621I557-F573 HydrophobicContact CB-CE1 4.49Å; I557-F573 HydrophobicContact CB-CE2 3.68Å; I557-F573 HydrophobicContact CB-CZ 3.58Å; I557-F573 HydrophobicContact CD1-CE2 4.11Å; I557-F573 HydrophobicContact CG1-CE2 4.45Å; I557-F573 HydrophobicContact CG2-CD2 4.14Å; I557-F573 HydrophobicContact CG2-CE1 4.07Å; I557-F573 HydrophobicContact CG2-CE2 3.59Å; I557-F573 HydrophobicContact CG2-CZ 3.54Å; I557-F573 WeakPolarHBondContact O-CZ 3.31Å; L559-F573 HydrophobicContact CB-CD1 3.76Å; L559-F573 HydrophobicContact CB-CE1 4.13Å; L559-F573 HydrophobicContact CD2-CB 4.45Å; L559-F573 HydrophobicContact CD2-CD1 4.21Å; F573-V575 HydrophobicContact CD2-CG2 4.41Å; F573-V575 HydrophobicContact CE2-CG2 4.45Å; F573-C597 HydrophobicContact CD1-CB 3.74Å; F573-C597 HydrophobicContact CD2-CB 4.13Å; F573-C597 HydrophobicContact CE1-CB 3.43Å; F573-C597 VanDerWaalsContact CE1-CB 3.43Å; F573-C597 HydrophobicContact CE2-CB 3.83Å; F573-C597 HydrophobicContact CG-CB 4.09Å; F573-C597 HydrophobicContact CZ-CB 3.47Å; F573-C597 VanDerWaalsContact CZ-CB 3.47Å; F573-C597 PolarHBondContact N-O 3.18Å; F573-C597 PolarHBondContact O-N 3.22Å; F573-V606 HydrophobicContact CD1-CG2 4.1Å; F573-V606 HydrophobicContact CE1-CG2 4.14Å; F573-L608 HydrophobicContact CE2-CB 3.86Å; F573-L608 HydrophobicContact CE2-CD2 4.07Å; F573-L608 HydrophobicContact CZ-CB 3.52Å; F573-V619 HydrophobicContact CB-CG2 4.1Å; F573-V619 HydrophobicContact CD2-CG2 3.78Å; F573-V619 HydrophobicContact CG-CG2 4.15Å; F573-V620 WeakPolarHBondContact CA-O 3.38Å; F573-P621 HydrophobicContact CB-CB 4.42Å
574H94.3Very high76.9Confident10 Ų1069.4 Ų69.45%0.04637%0.37CS..EExtended strand (participates in β ladder)trans-127.6147.7175.9-61.8-81.5000110.7Y533 Y576 P593 S596 V619 V620Y533-H574 AromaticContact CZ-CD2 3.93Å; Y533-H574 WeakPolarHBondContact OH-CB 3.48Å; Y533-H574 PolarHBondContact OH-CD2 2.94Å; H574-Y576 HydrophobicContact CB-CE2 3.68Å; H574-P593 HydrophobicContact CB-CB 3.93Å; H574-S596 VanDerWaalsContact ND1-CB 3.33Å; H574-S596 WeakPolarHBondContact ND1-CB 3.45Å; H574-S596 PolarHBondContact ND1-OG 3.38Å; H574-V619 WeakPolarHBondContact O-CA 3.3Å; H574-V620 PolarHBondContact N-O 3Å; H574-V620 VanDerWaalsContact N-O 3.15Å; H574-V620 PolarHBondContact O-N 3.41Å
575V92.9Very high75Confident0 Ų074 Ų740%039%0.385CS..EExtended strand (participates in β ladder)trans-113.5131176.8-174.70000108.6F541 I557 F573 P593 V594 A595 L612 Y617 T618 V619F541-V575 HydrophobicContact CE1-CG1 3.96Å; F541-V575 HydrophobicContact CZ-CG1 3.86Å; I557-V575 HydrophobicContact CD1-CG2 3.49Å; I557-V575 VanDerWaalsContact CD1-CG2 3.49Å; F573-V575 HydrophobicContact CD2-CG2 4.41Å; F573-V575 HydrophobicContact CE2-CG2 4.45Å; V575-P593 CarbonylContact O-C 3.58Å; V575-P593 WeakPolarHBondContact O-CA 3.12Å; V575-P593 WeakPolarHBondContact O-CB 3.38Å; V575-V594 HydrophobicContact CB-CG2 4.09Å; V575-V594 HydrophobicContact CG1-CG2 3.81Å; V575-V594 VanDerWaalsContact O-CG2 3.32Å; V575-V594 WeakPolarHBondContact O-CG2 3.25Å; V575-V594 PolarHBondContact O-N 3.08Å; V575-A595 HydrophobicContact CB-CB 4.12Å; V575-A595 HydrophobicContact CG2-CB 4.24Å; V575-A595 PolarHBondContact N-O 2.81Å; V575-L612 HydrophobicContact CG1-CD1 4.11Å; V575-Y617 HydrophobicContact CG1-CD1 4.21Å; V575-Y617 HydrophobicContact CG1-CG 4.49Å; V575-T618 CarbonylContact C-O 3.55Å; V575-T618 WeakPolarHBondContact CA-O 3.49Å; V575-V619 HydrophobicContact CG2-CG2 4.42Å
576Y90.1Very high73.4Confident0 Ų075.4 Ų75.40%040%0.397CS..EExtended strand (participates in β ladder)trans-120141.4178.1-61-88.5000110.1R528 Y533 W534 H574 E590 P593 Y617 T618 V620R528-Y576 VanDerWaalsContact CD-OH 3.29Å; R528-Y576 WeakPolarHBondContact CD-OH 3.34Å; R528-Y576 PolarHBondContact NE-OH 3.33Å; Y533-Y576 HydrophobicContact CE1-CE2 4.21Å; Y533-Y576 VanDerWaalsContact CE1-OH 3.25Å; Y533-Y576 WeakPolarHBondContact CE1-OH 3.43Å; Y533-Y576 WeakPolarHBondContact OH-CE2 3.35Å; Y533-Y576 PolarHBondContact OH-OH 3.03Å; W534-Y576 HydrophobicContact CH2-CD1 4.14Å; W534-Y576 HydrophobicContact CH2-CD2 4.32Å; W534-Y576 AromaticContact CH2-CE1 3.65Å; W534-Y576 HydrophobicContact CH2-CE1 3.65Å; W534-Y576 AromaticContact CH2-CE2 3.85Å; W534-Y576 HydrophobicContact CH2-CE2 3.85Å; W534-Y576 HydrophobicContact CH2-CG 4.44Å; W534-Y576 AromaticContact CH2-CZ 3.49Å; W534-Y576 VanDerWaalsContact CH2-CZ 3.49Å; W534-Y576 HydrophobicContact CZ2-CE1 4.49Å; W534-Y576 HydrophobicContact CZ3-CD2 4.23Å; W534-Y576 HydrophobicContact CZ3-CE1 4.46Å; W534-Y576 AromaticContact CZ3-CE2 3.84Å; W534-Y576 HydrophobicContact CZ3-CE2 3.84Å; W534-Y576 AromaticContact CZ3-CZ 3.98Å; H574-Y576 HydrophobicContact CB-CE2 3.68Å; Y576-E590 WeakPolarHBondContact CD1-O 3.47Å; Y576-P593 HydrophobicContact CD1-CB 4.26Å; Y576-P593 HydrophobicContact CE1-CB 3.87Å; Y576-Y617 CarbonylContact O-C 3.38Å; Y576-Y617 WeakPolarHBondContact O-CA 3.44Å; Y576-T618 PolarHBondContact N-O 2.85Å; Y576-T618 PolarHBondContact O-N 2.83Å; Y576-V620 HydrophobicContact CD2-CG2 3.87Å; Y576-V620 HydrophobicContact CE2-CB 4.27Å; Y576-V620 HydrophobicContact CE2-CG2 3.85Å
577K86.4Confident71.9Confident67 Ų6771.8 Ų71.829%0.29138%0.381SS..EExtended strand (participates in β ladder)trans-77.2135.7168.3-163.7171.3-174.5178.70109.3E590 V594 Y617K577-E590 WeakPolarHBondContact CB-OE2 3.19Å; K577-V594 HydrophobicContact CB-CG1 3.96Å; K577-Y617 HydrophobicContact CB-CD1 4.02Å; K577-Y617 HydrophobicContact CB-CE1 3.81Å; K577-Y617 HydrophobicContact CD-CE1 4.15Å; K577-Y617 HydrophobicContact CG-CD1 4.19Å; K577-Y617 HydrophobicContact CG-CE1 3.72Å
578V82.3Confident70.1Confident36 Ų3670.5 Ų70.522%0.21838%0.382CS..BIsolated β-bridgetrans-96.4116.2177.4-176.20000107.7A587 S616V578-A587 HydrophobicContact CG1-CB 3.9Å; V578-S616 PolarHBondContact N-O 2.72Å
579L69.6Low68.6Low87 Ų8772.9 Ų72.946%0.45539%0.391SS..PPolyproline II helixtrans-78.3122.2173.8-64.8171.2000108.6V581L579-V581 PolarHBondContact O-N 2.8Å
580Q53.1Low67Low184 Ų18475.5 Ų75.586%0.8640%0.403SS*.  trans-68.3100.2168.2-78-176-13.400107.8
581V43.3Very low65.5Low105 Ų10583.7 Ų83.764%0.63644%0.438SS*.  trans-109.5125162.4-175.70000106.1L579 S583L579-V581 PolarHBondContact O-N 2.8Å; V581-S583 VanDerWaalsContact C-N 3.33Å; V581-S583 PolarHBondContact O-N 2.82Å
582E39.4Very low64.8Low204 Ų20488.8 Ų88.895%0.95347%0.465SS*.SBendtrans-62.288.6174.3-68.5178.7152.800110.2
583S36.5Very low64.6Low97 Ų9790.1 Ų90.168%0.67847%0.473SS*.SBendtrans-174.8126.8152.4-167.30000109.3V581 Q585V581-S583 VanDerWaalsContact C-N 3.33Å; V581-S583 PolarHBondContact O-N 2.82Å; S583-Q585 VanDerWaalsContact C-N 3.33Å; S583-Q585 PolarHBondContact O-N 3.26Å
584E43.3Very low64.3Low188 Ų18892.9 Ų92.988%0.87949%0.49SS*.SBendtrans-66.688.6172.6-70.1-177.4151.700110.4
585Q40.8Very low64.1Low176 Ų17693 Ų9382%0.82249%0.493SS*.SBendtrans163.9122.1142.9-87.9158.73600107.5S583S583-Q585 VanDerWaalsContact C-N 3.33Å; S583-Q585 PolarHBondContact O-N 3.26Å
586T44.1Very low64Low142 Ų14294.9 Ų94.987%0.87151%0.506SS*.  trans66.579.7-173.929.60000116.4A588T586-A588 PolarHBondContact O-N 3.01Å
587A45.3Very low64.1Low61 Ų6195.8 Ų95.850%0.50451%0.513SS..  trans-55.6121.8160.300000109.9V578 K589V578-A587 HydrophobicContact CG1-CB 3.9Å; A587-K589 PolarHBondContact O-N 2.78Å; A587-K589 VanDerWaalsContact O-N 3.12Å
588A49.1Very low64Low53 Ų5396.2 Ų96.244%0.43852%0.52SS..  trans-65.2111.4178.100000109.5T586T586-A588 PolarHBondContact O-N 3.01Å
589K58.4Low64.1Low77 Ų7799.5 Ų99.534%0.33554%0.542SS..BIsolated β-bridgetrans-76.9134.6170.2-62.4179.2-175.8175.50108.1W534 C538 A587 K591W534-K589 HydrophobicContact CE3-CD 3.98Å; W534-K589 HydrophobicContact CH2-CB 4.49Å; W534-K589 HydrophobicContact CH2-CD 4.01Å; W534-K589 HydrophobicContact CZ3-CD 3.47Å; W534-K589 VanDerWaalsContact CZ3-CD 3.47Å; C538-K589 PolarHBondContact SG-NZ 3.26Å; A587-K589 PolarHBondContact O-N 2.78Å; A587-K589 VanDerWaalsContact O-N 3.12Å; K589-K591 PolarHBondContact O-N 2.93Å
590E59.9Low65.1Low82 Ų8296.6 Ų96.638%0.38353%0.527SS..  trans-53.7136.4170.4-156.5166-155.600109.4Y576 K577 D592 V594Y576-E590 WeakPolarHBondContact CD1-O 3.47Å; K577-E590 WeakPolarHBondContact CB-OE2 3.19Å; E590-D592 PolarHBondContact O-N 3.21Å; E590-V594 WeakPolarHBondContact OE2-CG1 3.17Å
591K62.3Low66.4Low188 Ų18890.2 Ų90.282%0.81750%0.502SS*.SBendtrans-63.8-27.4-174.1-80.5-173.2176.5179.70112.4R528 K589R528-K591 PolarHBondContact NH2-O 2.82Å; R528-K591 VanDerWaalsContact NH2-O 3.1Å; K589-K591 PolarHBondContact O-N 2.93Å
592D80.3Confident68.5Low107 Ų10793.3 Ų93.357%0.57250%0.503SS*.SBendtrans-113.1142.3178-71.8-45.9000112.4R528 E590R528-D592 IonicContact NH2-OD1 3.13Å; R528-D592 PolarHBondContact NH2-OD1 3.26Å; R528-D592 VanDerWaalsContact NH2-OD1 3.13Å; E590-D592 PolarHBondContact O-N 3.21Å
593P89.5Confident70.6Confident27 Ų2786.2 Ų86.218%0.17547%0.474CS..  trans-72.6135.3179.830.2-34.8000110.9H574 V575 Y576 A595 S596H574-P593 HydrophobicContact CB-CB 3.93Å; V575-P593 CarbonylContact O-C 3.58Å; V575-P593 WeakPolarHBondContact O-CA 3.12Å; V575-P593 WeakPolarHBondContact O-CB 3.38Å; Y576-P593 HydrophobicContact CD1-CB 4.26Å; Y576-P593 HydrophobicContact CE1-CB 3.87Å; P593-A595 VanDerWaalsContact C-N 3.25Å; P593-A595 PolarHBondContact O-N 3.11Å; P593-S596 VanDerWaalsContact CG-OG 3.25Å; P593-S596 WeakPolarHBondContact CG-OG 3.3Å
594V90.1Very high73.1Confident59 Ų5985 Ų8536%0.35846%0.457SS..SBendtrans-71.4-21.7174.6-64.80000112.7V575 K577 E590 L612 Y617V575-V594 HydrophobicContact CB-CG2 4.09Å; V575-V594 HydrophobicContact CG1-CG2 3.81Å; V575-V594 VanDerWaalsContact O-CG2 3.32Å; V575-V594 WeakPolarHBondContact O-CG2 3.25Å; V575-V594 PolarHBondContact O-N 3.08Å; K577-V594 HydrophobicContact CB-CG1 3.96Å; E590-V594 WeakPolarHBondContact OE2-CG1 3.17Å; V594-L612 HydrophobicContact CB-CD2 4.38Å; V594-L612 HydrophobicContact CG2-CD2 3.88Å; V594-Y617 HydrophobicContact CG2-CD1 3.91Å; V594-Y617 HydrophobicContact CG2-CE1 3.94Å
595A89.8Confident75.2Confident13 Ų1379.4 Ų79.411%0.10743%0.434CS..EExtended strand (participates in β ladder)trans-155.7145.4174.500000110.1V575 P593 L608 C610 L612V575-A595 HydrophobicContact CB-CB 4.12Å; V575-A595 HydrophobicContact CG2-CB 4.24Å; V575-A595 PolarHBondContact N-O 2.81Å; P593-A595 VanDerWaalsContact C-N 3.25Å; P593-A595 PolarHBondContact O-N 3.11Å; A595-L608 HydrophobicContact CB-CD2 3.68Å; A595-C610 HydrophobicContact CB-CB 4.24Å; A595-L612 HydrophobicContact CB-CD2 4.5Å
596S90.7Very high77.3Confident39 Ų3971.7 Ų71.727%0.27340%0.399SS..EExtended strand (participates in β ladder)trans-141.8140.6-178.1-56.80000111.6H574 P593H574-S596 VanDerWaalsContact ND1-CB 3.33Å; H574-S596 WeakPolarHBondContact ND1-CB 3.45Å; H574-S596 PolarHBondContact ND1-OG 3.38Å; P593-S596 VanDerWaalsContact CG-OG 3.25Å; P593-S596 WeakPolarHBondContact CG-OG 3.3Å
597C91.2Very high79.6Confident20 Ų2068.5 Ų68.514%0.13538%0.382CS..EExtended strand (participates in β ladder)trans-108.286169.5-165.50000107.8G572 F573 S607 L608G572-C597 WeakPolarHBondContact CA-O 3.48Å; F573-C597 HydrophobicContact CD1-CB 3.74Å; F573-C597 HydrophobicContact CD2-CB 4.13Å; F573-C597 HydrophobicContact CE1-CB 3.43Å; F573-C597 VanDerWaalsContact CE1-CB 3.43Å; F573-C597 HydrophobicContact CE2-CB 3.83Å; F573-C597 HydrophobicContact CG-CB 4.09Å; F573-C597 HydrophobicContact CZ-CB 3.47Å; F573-C597 VanDerWaalsContact CZ-CB 3.47Å; F573-C597 PolarHBondContact N-O 3.18Å; F573-C597 PolarHBondContact O-N 3.22Å; C597-S607 PolarHBondContact SG-O 3.36Å; C597-L608 HydrophobicContact CB-CB 4.06Å
598V84.6Confident81.6Confident75 Ų7567.4 Ų67.446%0.45537%0.367SS..EExtended strand (participates in β ladder)trans-140.8155-177.4-68.30000109.3
599P84.4Confident83.5Confident105 Ų10567.6 Ų67.668%0.68237%0.369SS*.EExtended strand (participates in β ladder)cis-67.2160.54.930.1-36.4000113.5C601P599-C601 PolarHBondContact O-N 2.94Å; P599-C601 PolarHBondContact O-SG 3.21Å; P599-C601 VanDerWaalsContact O-SG 3.34Å
600H91.1Very high84.7Confident27 Ų2764.8 Ų64.813%0.12536%0.359CS..EExtended strand (participates in β ladder)trans-64.9131.3171.8-68.766.5000109.8P570 I571 G572 S622 T623 Y624P570-H600 HydrophobicContact CB-CB 3.98Å; I571-H600 VanDerWaalsContact C-CD2 3.46Å; I571-H600 WeakPolarHBondContact O-CA 3.35Å; G572-H600 PolarHBondContact N-CD2 3.04Å; H600-S622 PolarHBondContact CD2-O 3.33Å; H600-S622 VanDerWaalsContact CD2-O 3.31Å; H600-S622 PolarHBondContact NE2-O 2.95Å; H600-S622 PolarHBondContact NE2-OG 2.7Å; H600-T623 VanDerWaalsContact CD2-C 3.5Å; H600-Y624 HydrophobicContact CB-CD2 4.16Å; H600-Y624 HydrophobicContact CB-CG 4.46Å; H600-Y624 PolarHBondContact CD2-N 3.15Å
601C81Confident86Confident50 Ų5064.2 Ų64.234%0.33837%0.368SS..EExtended strand (participates in β ladder)trans-122.9146.1-172.9-67.70000112P570 I571 P599 T603 V606P570-C601 VanDerWaalsContact CA-O 3.3Å; P570-C601 WeakPolarHBondContact CA-O 3.24Å; I571-C601 PolarHBondContact N-O 2.78Å; I571-C601 PolarHBondContact O-N 3.19Å; P599-C601 PolarHBondContact O-N 2.94Å; P599-C601 PolarHBondContact O-SG 3.21Å; P599-C601 VanDerWaalsContact O-SG 3.34Å; C601-T603 HydrophobicContact CB-CG2 4.09Å; C601-T603 PolarHBondContact O-N 2.99Å; C601-V606 HydrophobicContact CB-CG1 4.4Å
602Y86Confident87.1Confident170 Ų17055.6 Ų55.667%0.66733%0.331SS*.SBendtrans-74.369171.9-71.2-85.5000110.6L568 P570L568-Y602 VanDerWaalsContact O-CD1 3.22Å; L568-Y602 WeakPolarHBondContact O-CD1 3.2Å; L568-Y602 WeakPolarHBondContact O-CE1 3.43Å; P570-Y602 HydrophobicContact CB-CD2 4.32Å; P570-Y602 HydrophobicContact CB-CE1 4.43Å; P570-Y602 HydrophobicContact CB-CE2 4.15Å; P570-Y602 HydrophobicContact CG-CE1 4.21Å; P570-Y602 HydrophobicContact CG-CE2 4.39Å
603T83.1Confident87.2Confident55 Ų5554 Ų5434%0.33733%0.327SS..SBendtrans-132.6152.6-179.959.10000110.3Q561 C601 D605 V606Q561-T603 PolarHBondContact NE2-O 2.71Å; C601-T603 HydrophobicContact CB-CG2 4.09Å; C601-T603 PolarHBondContact O-N 2.99Å; T603-D605 WeakPolarHBondContact CB-O 3.32Å; T603-D605 PolarHBondContact O-N 3.05Å; T603-D605 PolarHBondContact OG1-O 3.27Å; T603-V606 VanDerWaalsContact OG1-CG1 3.26Å; T603-V606 WeakPolarHBondContact OG1-CG1 3.22Å
604Q89.2Confident86.9Confident71 Ų7155.8 Ų55.833%0.33234%0.338SS..SBendtrans-66.2-30.7176.1-166.7161.258.200111.4H560 Q561 R563 D565 L568H560-Q604 WeakPolarHBondContact CA-O 3.49Å; Q561-Q604 PolarHBondContact N-O 3.06Å; R563-Q604 PolarHBondContact O-NE2 3.05Å; D565-Q604 PolarHBondContact OD1-NE2 2.7Å; L568-Q604 HydrophobicContact CD2-CB 4.48Å
605D89Confident86.6Confident71 Ų7154.2 Ų54.238%0.3833%0.333SS..EExtended strand (participates in β ladder)trans-134.9143.5179.3-67.4-81.2000112.1T558 L559 H560 T603T558-D605 HydrophobicContact CG2-CB 4.37Å; L559-D605 WeakPolarHBondContact O-CA 3.14Å; H560-D605 WeakPolarHBondContact CA-OD1 3.44Å; H560-D605 WeakPolarHBondContact CB-OD1 3.48Å; H560-D605 IonicContact CE1-OD2 3.3Å; H560-D605 IonicContact CG-OD1 3.99Å; H560-D605 VanDerWaalsContact CG-OD1 3.25Å; H560-D605 IonicContact ND1-OD1 2.66Å; H560-D605 PolarHBondContact ND1-OD1 2.68Å; H560-D605 IonicContact ND1-OD2 3.69Å; H560-D605 PolarHBondContact ND1-OD2 2.83Å; T603-D605 WeakPolarHBondContact CB-O 3.32Å; T603-D605 PolarHBondContact O-N 3.05Å; T603-D605 PolarHBondContact OG1-O 3.27Å
606V84.4Confident86.4Confident14 Ų1455.8 Ų55.89%0.08534%0.344CS..EExtended strand (participates in β ladder)trans-129141164.6-65.20000109.7T558 L559 I571 F573 C601 T603T558-V606 CarbonylContact C-O 3.51Å; T558-V606 WeakPolarHBondContact CA-O 3.11Å; L559-V606 HydrophobicContact CB-CG2 3.87Å; L559-V606 HydrophobicContact CD2-CG2 4.22Å; L559-V606 HydrophobicContact CG-CG2 4.42Å; L559-V606 PolarHBondContact N-O 3.38Å; L559-V606 PolarHBondContact O-N 3.07Å; I571-V606 HydrophobicContact CD1-CG1 4.47Å; I571-V606 HydrophobicContact CD1-CG2 4.16Å; I571-V606 HydrophobicContact CG1-CG1 4.07Å; I571-V606 HydrophobicContact CG1-CG2 4.14Å; F573-V606 HydrophobicContact CD1-CG2 4.1Å; F573-V606 HydrophobicContact CE1-CG2 4.14Å; C601-V606 HydrophobicContact CB-CG1 4.4Å; T603-V606 VanDerWaalsContact OG1-CG1 3.26Å; T603-V606 WeakPolarHBondContact OG1-CG1 3.22Å
607S91.5Very high86.3Confident74 Ų7454 Ų5452%0.51733%0.331SS..EExtended strand (participates in β ladder)trans-135.5144.9-174.8-63.50000112.9I557 T558 C597I557-S607 CarbonylContact O-C 3.48Å; I557-S607 VanDerWaalsContact O-CA 3.23Å; I557-S607 WeakPolarHBondContact O-CA 3.36Å; T558-S607 WeakPolarHBondContact CB-OG 3.43Å; T558-S607 VanDerWaalsContact CG2-OG 3.25Å; T558-S607 WeakPolarHBondContact CG2-OG 3.27Å; T558-S607 PolarHBondContact OG1-OG 2.84Å; C597-S607 PolarHBondContact SG-O 3.36Å
608L88.1Confident86.3Confident38 Ų3853.5 Ų53.520%0.19933%0.328CS..EExtended strand (participates in β ladder)trans-131129.4173.9-176.166.2000110.5R556 I557 F573 A595 C597 C610R556-L608 CarbonylContact C-O 3.59Å; R556-L608 WeakPolarHBondContact CA-O 3.29Å; I557-L608 PolarHBondContact N-O 2.66Å; I557-L608 PolarHBondContact O-N 3.09Å; F573-L608 HydrophobicContact CE2-CB 3.86Å; F573-L608 HydrophobicContact CE2-CD2 4.07Å; F573-L608 HydrophobicContact CZ-CB 3.52Å; A595-L608 HydrophobicContact CB-CD2 3.68Å; C597-L608 HydrophobicContact CB-CB 4.06Å; L608-C610 HydrophobicContact CG-CB 4.48Å
609A88.8Confident86.7Confident58 Ų5850 Ų5048%0.47931%0.306SS..EExtended strand (participates in β ladder)trans-106.6121.7168.600000108.2V553 R556V553-A609 HydrophobicContact CG1-CB 3.69Å; V553-A609 HydrophobicContact CG2-CB 4.27Å; R556-A609 HydrophobicContact CG-CB 4.13Å
610C83.9Confident87.2Confident18 Ų1845 Ų4512%0.12227%0.273CS..EExtended strand (participates in β ladder)trans-141.3164.5-179.560.90000112.4V553 N554 V555 A595 L608V553-C610 WeakPolarHBondContact CG1-O 3.49Å; N554-C610 PolarHBondContact N-O 3.21Å; N554-C610 VanDerWaalsContact N-O 3.14Å; N554-C610 PolarHBondContact OD1-O 3.23Å; V555-C610 PolarHBondContact N-O 2.82Å; V555-C610 PolarHBondContact O-N 3.1Å; V555-C610 VanDerWaalsContact O-O 3.09Å; A595-C610 HydrophobicContact CB-CB 4.24Å; L608-C610 HydrophobicContact CG-CB 4.48Å
611A87.1Confident87.5Confident69 Ų6943.7 Ų43.757%0.5727%0.267SS*.  trans-105116.8170.800000108.6N554N554-A611 VanDerWaalsContact OD1-CA 3.27Å; N554-A611 WeakPolarHBondContact OD1-CA 3.48Å
612L85.3Confident88.2Confident8 Ų841.3 Ų41.34%0.04225%0.251CS..  trans-114.6131177.6-63.5-179000109.8F541 V543 N554 V555 V575 V594 A595 Y617F541-L612 HydrophobicContact CE2-CD1 3.99Å; F541-L612 HydrophobicContact CZ-CD1 3.77Å; V543-L612 HydrophobicContact CG2-CB 4.35Å; N554-L612 PolarHBondContact ND2-O 3.32Å; N554-L612 PolarHBondContact OD1-N 2.64Å; V555-L612 HydrophobicContact CB-CD1 4.28Å; V555-L612 HydrophobicContact CG1-CD1 4.29Å; V555-L612 HydrophobicContact CG2-CB 4.32Å; V555-L612 HydrophobicContact CG2-CD1 4.11Å; V555-L612 HydrophobicContact CG2-CG 4.37Å; V575-L612 HydrophobicContact CG1-CD1 4.11Å; V594-L612 HydrophobicContact CB-CD2 4.38Å; V594-L612 HydrophobicContact CG2-CD2 3.88Å; A595-L612 HydrophobicContact CB-CD2 4.5Å; L612-Y617 HydrophobicContact CB-CE1 4.42Å; L612-Y617 HydrophobicContact CB-CE2 4.1Å; L612-Y617 HydrophobicContact CD1-CD1 4.17Å; L612-Y617 HydrophobicContact CD1-CD2 4.32Å; L612-Y617 HydrophobicContact CD1-CE1 4.3Å; L612-Y617 HydrophobicContact CD1-CE2 4.43Å; L612-Y617 HydrophobicContact CD1-CG 4.2Å; L612-Y617 HydrophobicContact CD2-CE1 4.29Å
613P83.2Confident88.7Confident74 Ų7433.2 Ų33.248%0.48122%0.22SC..  trans-65.4163.9174.625.9-31.3000111.1G615 Y617P613-G615 PolarHBondContact O-N 2.84Å; P613-Y617 VanDerWaalsContact CD-OH 3.29Å; P613-Y617 WeakPolarHBondContact CD-OH 3.34Å; P613-Y617 WeakPolarHBondContact CG-OH 3.33Å; P613-Y617 VanDerWaalsContact O-CE2 3.26Å; P613-Y617 WeakPolarHBondContact O-CE2 3.49Å; P613-Y617 PolarHBondContact O-OH 2.76Å
614P82.3Confident89.2Confident63 Ų6335.6 Ų35.641%0.40922%0.223SC..SBendtrans-54.6138.5176-29.640.4000112.2V543 D545V543-P614 CarbonylContact O-C 3.56Å; V543-P614 VanDerWaalsContact O-CA 3.28Å; V543-P614 WeakPolarHBondContact O-CA 3.48Å; D545-P614 WeakPolarHBondContact O-CG 3.46Å
615G83.4Confident89.4Confident26 Ų2637.9 Ų37.927%0.26823%0.234SC..EExtended strand (participates in β ladder)trans152.3178.6-176.800000113.7A542 V543 P613 Y617A542-G615 WeakPolarHBondContact CA-O 3.46Å; V543-G615 PolarHBondContact N-O 2.75Å; V543-G615 PolarHBondContact O-N 2.83Å; P613-G615 PolarHBondContact O-N 2.84Å; G615-Y617 WeakPolarHBondContact O-CD2 3.48Å; G615-Y617 WeakPolarHBondContact O-CE2 3.44Å
616S85.3Confident89.6Confident46 Ų4636.1 Ų36.132%0.32223%0.226SC..EExtended strand (participates in β ladder)trans-95.7136.4175.9-58.40000110.7V578V578-S616 PolarHBondContact N-O 2.72Å
617Y89.8Confident90Very high2 Ų239.1 Ų39.11%0.00824%0.242CC..EExtended strand (participates in β ladder)trans-133.6164.5-176.1-63.3-84.8000110.7P540 F541 V543 V575 Y576 K577 V594 L612 P613 G615P540-Y617 CarbonylContact C-O 3.48Å; P540-Y617 VanDerWaalsContact CA-O 3.26Å; P540-Y617 WeakPolarHBondContact CA-O 3.41Å; F541-Y617 VanDerWaalsContact CE1-CB 3.47Å; F541-Y617 HydrophobicContact CE2-CD2 4.06Å; F541-Y617 HydrophobicContact CE2-CG 4.17Å; F541-Y617 HydrophobicContact CZ-CD2 4.37Å; F541-Y617 HydrophobicContact CZ-CG 4.01Å; F541-Y617 PolarHBondContact N-O 3.15Å; F541-Y617 PolarHBondContact O-N 3.2Å; F541-Y617 VanDerWaalsContact O-O 3.1Å; V543-Y617 HydrophobicContact CB-CE2 4.2Å; V543-Y617 HydrophobicContact CG2-CD2 3.94Å; V543-Y617 HydrophobicContact CG2-CE2 3.88Å; V575-Y617 HydrophobicContact CG1-CD1 4.21Å; V575-Y617 HydrophobicContact CG1-CG 4.49Å; Y576-Y617 CarbonylContact O-C 3.38Å; Y576-Y617 WeakPolarHBondContact O-CA 3.44Å; K577-Y617 HydrophobicContact CB-CD1 4.02Å; K577-Y617 HydrophobicContact CB-CE1 3.81Å; K577-Y617 HydrophobicContact CD-CE1 4.15Å; K577-Y617 HydrophobicContact CG-CD1 4.19Å; K577-Y617 HydrophobicContact CG-CE1 3.72Å; V594-Y617 HydrophobicContact CG2-CD1 3.91Å; V594-Y617 HydrophobicContact CG2-CE1 3.94Å; L612-Y617 HydrophobicContact CB-CE1 4.42Å; L612-Y617 HydrophobicContact CB-CE2 4.1Å; L612-Y617 HydrophobicContact CD1-CD1 4.17Å; L612-Y617 HydrophobicContact CD1-CD2 4.32Å; L612-Y617 HydrophobicContact CD1-CE1 4.3Å; L612-Y617 HydrophobicContact CD1-CE2 4.43Å; L612-Y617 HydrophobicContact CD1-CG 4.2Å; L612-Y617 HydrophobicContact CD2-CE1 4.29Å; P613-Y617 VanDerWaalsContact CD-OH 3.29Å; P613-Y617 WeakPolarHBondContact CD-OH 3.34Å; P613-Y617 WeakPolarHBondContact CG-OH 3.33Å; P613-Y617 VanDerWaalsContact O-CE2 3.26Å; P613-Y617 WeakPolarHBondContact O-CE2 3.49Å; P613-Y617 PolarHBondContact O-OH 2.76Å; G615-Y617 WeakPolarHBondContact O-CD2 3.48Å; G615-Y617 WeakPolarHBondContact O-CE2 3.44Å
618T89.9Confident90.1Very high10 Ų1036.5 Ų36.56%0.06122%0.224CC..EExtended strand (participates in β ladder)trans-135.2133.3170.5-109.90000109.5C538 F539 P540 V575 Y576 V620C538-T618 HydrophobicContact CB-CG2 4.01Å; F539-T618 WeakPolarHBondContact O-CA 2.85Å; P540-T618 WeakPolarHBondContact CA-OG1 3.24Å; V575-T618 CarbonylContact C-O 3.55Å; V575-T618 WeakPolarHBondContact CA-O 3.49Å; Y576-T618 PolarHBondContact N-O 2.85Å; Y576-T618 PolarHBondContact O-N 2.83Å; T618-V620 HydrophobicContact CG2-CG2 3.68Å
619V93.9Very high90.3Very high0 Ų037.1 Ų37.10%023%0.231CC..EExtended strand (participates in β ladder)trans-96.7134.3168.862.10000110.2F539 F541 I557 F573 H574 V575 I634F539-V619 HydrophobicContact CB-CG1 3.76Å; F539-V619 HydrophobicContact CD2-CG1 4.43Å; F539-V619 PolarHBondContact N-O 2.82Å; F539-V619 PolarHBondContact O-N 3.32Å; F541-V619 HydrophobicContact CE1-CB 4.44Å; I557-V619 HydrophobicContact CD1-CB 4.46Å; I557-V619 HydrophobicContact CD1-CG2 4.36Å; I557-V619 HydrophobicContact CG2-CG2 4.22Å; F573-V619 HydrophobicContact CB-CG2 4.1Å; F573-V619 HydrophobicContact CD2-CG2 3.78Å; F573-V619 HydrophobicContact CG-CG2 4.15Å; H574-V619 WeakPolarHBondContact O-CA 3.3Å; V575-V619 HydrophobicContact CG2-CG2 4.42Å; V619-I634 HydrophobicContact CG1-CD1 3.94Å; V619-I634 HydrophobicContact CG1-CG2 4.44Å; V619-I634 HydrophobicContact CG2-CD1 4.49Å
620V95.4Very high90.5Very high0 Ų034.9 Ų34.90%021%0.212CC..EExtended strand (participates in β ladder)trans-119.893.4179.5-173.10000108.8Y533 N536 F573 H574 Y576 T618Y533-V620 HydrophobicContact CE1-CG1 4.27Å; Y533-V620 HydrophobicContact CE2-CG1 4.24Å; Y533-V620 WeakPolarHBondContact OH-CB 3.27Å; N536-V620 HydrophobicContact CB-CG1 3.67Å; F573-V620 WeakPolarHBondContact CA-O 3.38Å; H574-V620 PolarHBondContact N-O 3Å; H574-V620 VanDerWaalsContact N-O 3.15Å; H574-V620 PolarHBondContact O-N 3.41Å; Y576-V620 HydrophobicContact CD2-CG2 3.87Å; Y576-V620 HydrophobicContact CE2-CB 4.27Å; Y576-V620 HydrophobicContact CE2-CG2 3.85Å; T618-V620 HydrophobicContact CG2-CG2 3.68Å
621P96.4Very high91Very high0 Ų041.3 Ų41.30%024%0.238CC..EExtended strand (participates in β ladder)trans-72.8141.1172.532.9-40.2000111.8W518 N536 P537 F539 L559 F573 F632 I634W518-P621 HydrophobicContact CZ2-CB 3.96Å; W518-P621 PolarHBondContact NE1-O 2.81Å; N536-P621 WeakPolarHBondContact CB-O 3.45Å; P537-P621 VanDerWaalsContact O-CD 3.32Å; P537-P621 WeakPolarHBondContact O-CD 3.47Å; F539-P621 HydrophobicContact CD2-CG 4.2Å; F539-P621 HydrophobicContact CE2-CG 3.85Å; L559-P621 HydrophobicContact CD1-CB 3.72Å; L559-P621 HydrophobicContact CD2-CB 3.78Å; L559-P621 HydrophobicContact CG-CB 4.38Å; F573-P621 HydrophobicContact CB-CB 4.42Å; P621-F632 HydrophobicContact CB-CE2 4.11Å; P621-F632 HydrophobicContact CB-CZ 4.22Å; P621-F632 HydrophobicContact CG-CD2 4.41Å; P621-F632 HydrophobicContact CG-CE1 4.35Å; P621-F632 HydrophobicContact CG-CE2 3.53Å; P621-F632 HydrophobicContact CG-CZ 3.47Å; P621-F632 VanDerWaalsContact CG-CZ 3.47Å; P621-I634 HydrophobicContact CB-CD1 3.95Å; P621-I634 HydrophobicContact CB-CG1 4.49Å; P621-I634 HydrophobicContact CG-CD1 3.54Å; P621-I634 HydrophobicContact CG-CG1 4.48Å
622S96.3Very high91.4Very high0 Ų038.1 Ų38.10%021%0.211CC..EExtended strand (participates in β ladder)trans-146.5147.9-17755.60000111.9G526 G572 H600G526-S622 WeakPolarHBondContact O-CB 3.44Å; G572-S622 PolarHBondContact N-O 3.32Å; G572-S622 PolarHBondContact O-N 3.34Å; G572-S622 PolarHBondContact O-OG 3.18Å; H600-S622 PolarHBondContact CD2-O 3.33Å; H600-S622 VanDerWaalsContact CD2-O 3.31Å; H600-S622 PolarHBondContact NE2-O 2.95Å; H600-S622 PolarHBondContact NE2-OG 2.7Å
623T96.3Very high91.7Very high0 Ų039.5 Ų39.50%022%0.219CC..EExtended strand (participates in β ladder)trans-76.9161.5156.650.50000109.9W518 G526 S527 H569 P570 I571 H600 Q625 C628W518-T623 HydrophobicContact CD2-CG2 3.84Å; W518-T623 HydrophobicContact CE3-CG2 3.65Å; W518-T623 HydrophobicContact CG-CG2 4.4Å; W518-T623 HydrophobicContact CH2-CG2 4.32Å; W518-T623 HydrophobicContact CZ2-CG2 4.46Å; W518-T623 HydrophobicContact CZ3-CG2 3.91Å; G526-T623 CarbonylContact C-O 3.27Å; G526-T623 WeakPolarHBondContact CA-O 3.15Å; S527-T623 PolarHBondContact N-O 2.93Å; H569-T623 HydrophobicContact CB-CG2 3.98Å; P570-T623 CarbonylContact O-C 3.15Å; P570-T623 WeakPolarHBondContact O-CA 3.12Å; I571-T623 HydrophobicContact CG2-CG2 4.41Å; H600-T623 VanDerWaalsContact CD2-C 3.5Å; T623-Q625 PolarHBondContact OG1-O 2.83Å; T623-C628 HydrophobicContact CG2-CB 3.76Å
624Y93.8Very high91.9Very high106 Ų10636 Ų3642%0.41620%0.196SC..SBendtrans-63.9-52.8176.9-177-110.3000111.8S527 F530 P570 H600S527-Y624 WeakPolarHBondContact CB-O 3.37Å; S527-Y624 PolarHBondContact N-O 3.44Å; S527-Y624 PolarHBondContact OG-O 2.69Å; F530-Y624 WeakPolarHBondContact CE2-O 3.24Å; P570-Y624 VanDerWaalsContact CG-CB 3.46Å; P570-Y624 HydrophobicContact CG-CG 4.44Å; P570-Y624 PolarHBondContact O-N 3.44Å; H600-Y624 HydrophobicContact CB-CD2 4.16Å; H600-Y624 HydrophobicContact CB-CG 4.46Å; H600-Y624 PolarHBondContact CD2-N 3.15Å
625Q93.6Very high92.3Very high118 Ų11834.4 Ų34.455%0.55119%0.186SC*.SBendtrans-90148.5176.8-69-174.1-15.500111.3T623T623-Q625 PolarHBondContact OG1-O 2.83Å
626P93.1Very high92.4Very high34 Ų3433.3 Ų33.322%0.22117%0.174CC..THydrogen-bonded Turntrans-63.9166.3169.129.5-34.4000111.2A524 F530 C628A524-P626 CarbonylContact O-C 3.6Å; A524-P626 WeakPolarHBondContact O-CA 3.44Å; F530-P626 HydrophobicContact CD1-CG 3.99Å; F530-P626 HydrophobicContact CE1-CG 4.16Å; F530-P626 HydrophobicContact CG-CG 4.35Å; P626-C628 PolarHBondContact O-N 3.41Å
627D93.6Very high92.4Very high78 Ų7831.3 Ų31.342%0.41716%0.16SC..THydrogen-bonded Turntrans63.35.7173.6-61.4-45.1000116.6E520 G521 A524 S629E520-D627 HydrophobicContact CB-CB 4.48Å; E520-D627 HydrophobicContact CG-CB 3.94Å; G521-D627 PolarHBondContact N-OD1 3.07Å; A524-D627 PolarHBondContact O-N 2.93Å; D627-S629 PolarHBondContact O-N 3.24Å
628C91.9Very high91.9Very high19 Ų1934 Ų3413%0.12817%0.17CC..  trans-74.9110.8172.2-65.60000111.3W518 T623 P626W518-C628 VanDerWaalsContact CB-O 3.23Å; W518-C628 WeakPolarHBondContact CB-O 3.47Å; T623-C628 HydrophobicContact CG2-CB 3.76Å; P626-C628 PolarHBondContact O-N 3.41Å
629S93.2Very high91Very high50 Ų5034.7 Ų34.735%0.3517%0.173SC..  trans-89.3123.6-177.8-67.30000112.9W518 E520 R563 D627W518-S629 VanDerWaalsContact O-CA 3.25Å; W518-S629 WeakPolarHBondContact O-CA 3.2Å; E520-S629 PolarHBondContact N-OG 2.95Å; R563-S629 PolarHBondContact NH1-O 3.04Å; D627-S629 PolarHBondContact O-N 3.24Å
630A92.8Very high89.5Confident11 Ų1136.4 Ų36.49%0.09118%0.181CC..EExtended strand (participates in β ladder)trans-159.7155.2169.900000112.2S517 W518 R563S517-A630 CarbonylContact C-O 3.5Å; S517-A630 VanDerWaalsContact CA-O 3.27Å; S517-A630 WeakPolarHBondContact CA-O 3.39Å; W518-A630 HydrophobicContact CE3-CB 3.99Å; W518-A630 HydrophobicContact CZ3-CB 4.33Å; W518-A630 PolarHBondContact N-O 2.92Å; W518-A630 PolarHBondContact O-N 3.22Å; W518-A630 VanDerWaalsContact O-N 3.13Å; R563-A630 HydrophobicContact CG-CB 3.96Å
631K95.1Very high87.4Confident153 Ų15344.3 Ų44.367%0.66522%0.218SC*.EExtended strand (participates in β ladder)trans-83.8146.1168.3-68179.5-178.3174.70109.5S562S562-K631 PolarHBondContact N-O 3.03Å
632F94.3Very high85Confident2 Ų254 Ų541%0.00925%0.254CS..EExtended strand (participates in β ladder)trans-145.1164.1177.465.9-99000112.3G516 W518 P537 F539 L559 H560 P621 I634G516-F632 PolarHBondContact N-O 2.69Å; G516-F632 PolarHBondContact O-N 2.8Å; G516-F632 VanDerWaalsContact O-O 3.13Å; W518-F632 AromaticContact CD1-CE1 3.98Å; W518-F632 AromaticContact CD2-CD1 3.54Å; W518-F632 HydrophobicContact CD2-CD1 3.54Å; W518-F632 AromaticContact CD2-CE1 3.68Å; W518-F632 HydrophobicContact CD2-CE1 3.68Å; W518-F632 AromaticContact CE2-CD1 3.6Å; W518-F632 AromaticContact CE2-CE1 3.54Å; W518-F632 AromaticContact CE3-CD1 3.6Å; W518-F632 HydrophobicContact CE3-CD1 3.6Å; W518-F632 HydrophobicContact CE3-CE1 4.23Å; W518-F632 HydrophobicContact CE3-CG 4.49Å; W518-F632 HydrophobicContact CG-CD1 4.23Å; W518-F632 AromaticContact CG-CE1 3.98Å; W518-F632 HydrophobicContact CG-CE1 3.98Å; W518-F632 HydrophobicContact CH2-CB 4.06Å; W518-F632 AromaticContact CH2-CD1 3.81Å; W518-F632 HydrophobicContact CH2-CD1 3.81Å; W518-F632 HydrophobicContact CH2-CG 4.06Å; W518-F632 AromaticContact CZ2-CD1 3.76Å; W518-F632 HydrophobicContact CZ2-CD1 3.76Å; W518-F632 HydrophobicContact CZ2-CE1 4.01Å; W518-F632 HydrophobicContact CZ2-CG 4.22Å; W518-F632 HydrophobicContact CZ3-CB 4.02Å; W518-F632 AromaticContact CZ3-CD1 3.74Å; W518-F632 HydrophobicContact CZ3-CD1 3.74Å; W518-F632 HydrophobicContact CZ3-CG 4.2Å; W518-F632 AromaticContact NE1-CE1 3.7Å; P537-F632 HydrophobicContact CB-CZ 4.07Å; P537-F632 HydrophobicContact CG-CE1 4.17Å; P537-F632 HydrophobicContact CG-CZ 3.9Å; F539-F632 AromaticContact CE2-CE2 3.71Å; F539-F632 HydrophobicContact CE2-CE2 3.71Å; F539-F632 AromaticContact CE2-CZ 3.86Å; F539-F632 HydrophobicContact CE2-CZ 3.86Å; F539-F632 HydrophobicContact CZ-CE2 4Å; F539-F632 HydrophobicContact CZ-CZ 4.13Å; L559-F632 HydrophobicContact CD1-CB 3.92Å; L559-F632 HydrophobicContact CD1-CD2 3.54Å; L559-F632 HydrophobicContact CD1-CE2 4.28Å; L559-F632 HydrophobicContact CD1-CG 3.88Å; H560-F632 CarbonylContact O-C 3.58Å; H560-F632 WeakPolarHBondContact O-CA 3.5Å; H560-F632 WeakPolarHBondContact O-CB 3.4Å; P621-F632 HydrophobicContact CB-CE2 4.11Å; P621-F632 HydrophobicContact CB-CZ 4.22Å; P621-F632 HydrophobicContact CG-CD2 4.41Å; P621-F632 HydrophobicContact CG-CE1 4.35Å; P621-F632 HydrophobicContact CG-CE2 3.53Å; P621-F632 HydrophobicContact CG-CZ 3.47Å; P621-F632 VanDerWaalsContact CG-CZ 3.47Å; F632-I634 HydrophobicContact CD2-CG1 4.24Å; F632-I634 HydrophobicContact CE2-CD1 4.03Å; F632-I634 HydrophobicContact CE2-CG1 4.19Å
633I92.3Very high82.1Confident38 Ų3863.7 Ų63.720%0.19530%0.297CS..EExtended strand (participates in β ladder)trans-127.4130173.9-55-179.8000107.8F513 F514 R515 H560F513-I633 HydrophobicContact CD1-CG2 4.19Å; F514-I633 CarbonylContact O-C 3.51Å; F514-I633 WeakPolarHBondContact O-CA 3.48Å; R515-I633 HydrophobicContact CG-CG1 4.36Å; H560-I633 HydrophobicContact CB-CB 4.44Å; H560-I633 PolarHBondContact N-O 3.3Å; H560-I633 PolarHBondContact O-N 2.77Å
634I87.9Confident79Confident1 Ų170.5 Ų70.51%0.00534%0.338CS..EExtended strand (participates in β ladder)trans-98.6125.5165-66.2163.5000108.5F513 F514 F539 I557 T558 L559 V619 P621 F632F513-I634 CarbonylContact C-O 3.56Å; F513-I634 VanDerWaalsContact CA-O 3.29Å; F513-I634 WeakPolarHBondContact CA-O 3.26Å; F514-I634 HydrophobicContact CB-CB 4.32Å; F514-I634 HydrophobicContact CD2-CB 4.47Å; F514-I634 HydrophobicContact CD2-CG2 4.36Å; F514-I634 PolarHBondContact N-O 3.5Å; F514-I634 PolarHBondContact O-N 2.9Å; F539-I634 HydrophobicContact CD2-CD1 3.44Å; F539-I634 VanDerWaalsContact CD2-CD1 3.44Å; F539-I634 HydrophobicContact CE2-CD1 3.71Å; F539-I634 HydrophobicContact CG-CD1 4.27Å; I557-I634 HydrophobicContact CG2-CG2 3.84Å; T558-I634 CarbonylContact O-C 3.51Å; T558-I634 VanDerWaalsContact O-CA 3.28Å; T558-I634 WeakPolarHBondContact O-CA 3.44Å; L559-I634 HydrophobicContact CD1-CG1 3.78Å; V619-I634 HydrophobicContact CG1-CD1 3.94Å; V619-I634 HydrophobicContact CG1-CG2 4.44Å; V619-I634 HydrophobicContact CG2-CD1 4.49Å; P621-I634 HydrophobicContact CB-CD1 3.95Å; P621-I634 HydrophobicContact CB-CG1 4.49Å; P621-I634 HydrophobicContact CG-CD1 3.54Å; P621-I634 HydrophobicContact CG-CG1 4.48Å; F632-I634 HydrophobicContact CD2-CG1 4.24Å; F632-I634 HydrophobicContact CE2-CD1 4.03Å; F632-I634 HydrophobicContact CE2-CG1 4.19Å
635S90.3Very high76Confident29 Ų2971.4 Ų71.420%0.20335%0.354CS..EExtended strand (participates in β ladder)trans-98.6116.6164.3-1770000108.5T511 F513 I557 T558T511-S635 WeakPolarHBondContact CG2-OG 3.25Å; F513-S635 WeakPolarHBondContact CE1-OG 3.33Å; I557-S635 CarbonylContact C-O 3.51Å; I557-S635 VanDerWaalsContact CA-O 3.3Å; I557-S635 WeakPolarHBondContact CA-O 3.11Å; T558-S635 PolarHBondContact N-O 3.47Å; T558-S635 PolarHBondContact O-N 2.85Å
636L86.4Confident73.2Confident3 Ų375 Ų752%0.01637%0.368CS..EExtended strand (participates in β ladder)trans-111.7106.9176.4171.471.9000108.7T511 S512 F514 F541 V555 R556 I557T511-L636 CarbonylContact C-O 3.48Å; T511-L636 VanDerWaalsContact CA-O 3.29Å; T511-L636 WeakPolarHBondContact CA-O 3.21Å; S512-L636 PolarHBondContact N-O 3.02Å; S512-L636 PolarHBondContact O-N 3.2Å; F514-L636 HydrophobicContact CE2-CB 4.06Å; F514-L636 HydrophobicContact CE2-CD2 3.94Å; F541-L636 HydrophobicContact CB-CD2 3.27Å; F541-L636 HydrophobicContact CD1-CD1 4.45Å; F541-L636 HydrophobicContact CD1-CD2 3.95Å; F541-L636 HydrophobicContact CD2-CD1 4.14Å; F541-L636 HydrophobicContact CD2-CD2 3.75Å; F541-L636 HydrophobicContact CE1-CD1 4.43Å; F541-L636 HydrophobicContact CE2-CD1 4.12Å; F541-L636 HydrophobicContact CG-CD1 4.3Å; F541-L636 HydrophobicContact CG-CD2 3.4Å; F541-L636 VanDerWaalsContact CG-CD2 3.4Å; F541-L636 HydrophobicContact CZ-CD1 4.26Å; V555-L636 HydrophobicContact CG1-CD1 3.68Å; R556-L636 CarbonylContact O-C 3.54Å; R556-L636 WeakPolarHBondContact O-CA 3.31Å; I557-L636 HydrophobicContact CD1-CD1 4.02Å; I557-L636 HydrophobicContact CG1-CD1 3.58Å
637A83.8Confident70.4Confident4 Ų477.5 Ų77.53%0.03339%0.387CS..EExtended strand (participates in β ladder)trans-98.1128.6171.100000110.5W509 E510 T511 V555 R556W509-A637 HydrophobicContact CE3-CB 3.9Å; E510-A637 CarbonylContact O-C 3.33Å; E510-A637 VanDerWaalsContact O-CA 3.3Å; E510-A637 WeakPolarHBondContact O-CA 3.46Å; T511-A637 HydrophobicContact CG2-CB 4.3Å; T511-A637 WeakPolarHBondContact OG1-CB 3.28Å; V555-A637 CarbonylContact C-O 3.52Å; V555-A637 WeakPolarHBondContact CA-O 3.2Å; R556-A637 HydrophobicContact CB-CB 4.25Å; R556-A637 PolarHBondContact N-O 3Å; R556-A637 PolarHBondContact O-N 3.3Å
638R79.1Confident67.7Low58 Ų5879 Ų7922%0.21939%0.391CS..EExtended strand (participates in β ladder)trans-123142.8173.263.1179.3-179.4-171.1-2.6110.3W509 E510 A542 N554 I640W509-R638 CarbonylContact C-O 3.55Å; W509-R638 VanDerWaalsContact CA-O 3.3Å; W509-R638 WeakPolarHBondContact CA-O 3.42Å; E510-R638 HydrophobicContact CB-CG 4.11Å; E510-R638 PolarHBondContact N-O 3.01Å; E510-R638 PolarHBondContact O-N 3.29Å; E510-R638 IonicContact OE1-NH2 3.71Å; E510-R638 IonicContact OE2-CZ 3.13Å; E510-R638 IonicContact OE2-NE 2.77Å; E510-R638 PolarHBondContact OE2-NE 3.45Å; E510-R638 IonicContact OE2-NH2 2.68Å; E510-R638 PolarHBondContact OE2-NH2 3.29Å; A542-R638 PolarHBondContact O-NH1 3Å; N554-R638 WeakPolarHBondContact O-CA 3.5Å; R638-I640 HydrophobicContact CG-CG2 4.27Å
639K71.4Confident65.4Low24 Ų2479.1 Ų79.110%0.10439%0.39CS..EExtended strand (participates in β ladder)trans-67.7137.9173.7-157.8170.3174.4170.10109.2D506 G507 E508 W509 N554D506-K639 WeakPolarHBondContact O-CE 3.44Å; D506-K639 PolarHBondContact O-NZ 3.02Å; D506-K639 IonicContact OD1-NZ 2.79Å; D506-K639 PolarHBondContact OD1-NZ 3.45Å; G507-K639 VanDerWaalsContact CA-CE 3.49Å; E508-K639 CarbonylContact O-C 3.57Å; E508-K639 WeakPolarHBondContact O-CA 3.4Å; W509-K639 HydrophobicContact CD2-CB 4.38Å; W509-K639 HydrophobicContact CE3-CB 4.49Å; W509-K639 HydrophobicContact CZ2-CB 4.41Å; W509-K639 HydrophobicContact CZ2-CD 4.46Å; N554-K639 HydrophobicContact CB-CB 4.29Å; N554-K639 PolarHBondContact O-N 3.19Å
640I61.7Low62.9Low36 Ų3682.5 Ų82.519%0.18540%0.398CS..EExtended strand (participates in β ladder)trans-139.2152.417658.6157.9000110.7E508 E510 R638E508-I640 HydrophobicContact CB-CG1 4.31Å; E508-I640 PolarHBondContact N-O 3.01Å; E508-I640 PolarHBondContact O-N 2.86Å; E508-I640 VanDerWaalsContact O-O 3.08Å; E510-I640 HydrophobicContact CB-CD1 3.75Å; E510-I640 HydrophobicContact CB-CG1 3.89Å; E510-I640 HydrophobicContact CB-CG2 3.87Å; E510-I640 HydrophobicContact CG-CD1 4.45Å; R638-I640 HydrophobicContact CG-CG2 4.27Å
641H51.3Low60.1Low166 Ų16683.8 Ų83.877%0.76940%0.403SS*.  trans-109.8108.6170.3-11478000110.4
642R46.2Very low57.5Low203 Ų20379.4 Ų79.477%0.76640%0.402SS*.  trans-134.6145.4170.6-80.5-170.9171.8169.70.1113
643K36.1Very low54.8Low205 Ų20581.9 Ų81.989%0.89142%0.419SS*.  trans-67.8141.2178.6-79.4-179.9175.5176.20112.2
644V31Very low52Low142 Ų14282.3 Ų82.386%0.86143%0.428SS*.  trans-25.2126-178.4-173.90000117
645V31.5Very low49.7Very low125 Ų12585.1 Ų85.176%0.75844%0.443SS*.  trans-109.4138.7170.9179.50000110.2
646K33.6Very low46.9Very low193 Ų19390.2 Ų90.284%0.83946%0.463SS*.  trans-98.4129.4173.8-75.4178.3177.2172.30110.3
647S34Very low44.3Very low88 Ų8898.5 Ų98.562%0.61550%0.502SS*.  trans-79.5146.7176.562.20000113
648Q37.5Very low41.8Very low109 Ų109102.8 Ų102.851%0.50953%0.527SS..  trans-128.4123.3172.2-68.6-170.49.500109.9
649E44.2Very low39.4Very low22 Ų22105.2 Ų105.210%0.10355%0.553CS.*EExtended strand (participates in β ladder)trans-108.2142.6179.8-66.7174.8-173.900111.2R429 F430R429-E649 VanDerWaalsContact CA-O 3.31Å; R429-E649 WeakPolarHBondContact CA-O 3.33Å; F430-E649 VanDerWaalsContact CE2-OE2 3.26Å; F430-E649 WeakPolarHBondContact CE2-OE2 3.37Å; F430-E649 HydrophobicContact CZ-CB 4.45Å; F430-E649 WeakPolarHBondContact CZ-OE2 3.26Å
650K40.5Very low37.5Very low121 Ų121111.1 Ų111.153%0.52658%0.581SS.*EExtended strand (participates in β ladder)trans-120.1138.8174.2-82-178.3-175173.70111.6K428 R429 G652 S653K428-K650 VanDerWaalsContact O-CA 3.31Å; K428-K650 WeakPolarHBondContact O-CA 3.47Å; R429-K650 HydrophobicContact CG-CG 3.91Å; K650-G652 PolarHBondContact O-N 3.17Å; K650-S653 PolarHBondContact O-OG 3.33Å
651L33.9Very low35.9Very low37 Ų37116.7 Ų116.719%0.19461%0.61CS.*THydrogen-bonded Turntrans-55.8125179.8-155.579.4000113W374 V425 K428 Y463 S653W374-L651 HydrophobicContact CH2-CD1 3.94Å; W374-L651 HydrophobicContact CZ2-CD1 4.42Å; W374-L651 HydrophobicContact CZ3-CD1 4.12Å; V425-L651 HydrophobicContact CB-CD1 4.42Å; V425-L651 HydrophobicContact CG1-CD1 3.94Å; K428-L651 HydrophobicContact CG-CB 4.49Å; K428-L651 HydrophobicContact CG-CD2 4.24Å; K428-L651 PolarHBondContact O-N 3.34Å; Y463-L651 HydrophobicContact CD1-CD1 4.09Å; Y463-L651 HydrophobicContact CD1-CD2 4.05Å; Y463-L651 HydrophobicContact CD1-CG 3.85Å; Y463-L651 HydrophobicContact CD2-CD1 4.24Å; Y463-L651 HydrophobicContact CD2-CD2 3.37Å; Y463-L651 HydrophobicContact CD2-CG 4.05Å; Y463-L651 HydrophobicContact CE1-CD2 4.07Å; Y463-L651 HydrophobicContact CE1-CG 4.07Å; Y463-L651 HydrophobicContact CE2-CD2 3.39Å; Y463-L651 HydrophobicContact CE2-CG 4.25Å; Y463-L651 HydrophobicContact CG-CD1 3.77Å; Y463-L651 HydrophobicContact CG-CD2 3.7Å; Y463-L651 HydrophobicContact CG-CG 3.82Å; L651-S653 PolarHBondContact O-N 3.19Å
652G41.5Very low34.6Very low62 Ų62114.4 Ų114.464%0.63961%0.612SS**THydrogen-bonded Turntrans78.38171.400000116.8K650K650-G652 PolarHBondContact O-N 3.17Å
653S36.7Very low33.8Very low53 Ų53110.2 Ų110.237%0.37161%0.609SS.*SBendtrans-125157.1176.555.70000112.3K650 L651K650-S653 PolarHBondContact O-OG 3.33Å; L651-S653 PolarHBondContact O-N 3.19Å
654A34.3Very low33.2Very low47 Ų47109.1 Ų109.139%0.38861%0.609SS.*  trans-58.8148168.600000110.8H656A654-H656 PolarHBondContact O-CD2 2.84Å; A654-H656 PolarHBondContact O-N 3.26Å
655I38.4Very low33.1Very low60 Ų60111.8 Ų111.831%0.30861%0.609SS.*  trans-58.9121-179.2-56.4-174.8000108.7
656H31.4Very low33.2Very low136 Ų136115.8 Ų115.863%0.6363%0.634SS**  trans-112.1113171.4-82.1-69.9000108.8A654 V658A654-H656 PolarHBondContact O-CD2 2.84Å; A654-H656 PolarHBondContact O-N 3.26Å; H656-V658 PolarHBondContact O-N 2.92Å
657E32.8Very low33.2Very low178 Ų178111.9 Ų111.983%0.83262%0.623SS**  trans-68.9125165.9-71.6-177.5162.500109
658V30.3Very low33.1Very low94 Ų94113.2 Ų113.257%0.5762%0.624SS**  trans-124.4114172.2-173.50000108.1H656H656-V658 PolarHBondContact O-N 2.92Å
659S30Very low32.9Very low109 Ų109113.4 Ų113.476%0.76263%0.63SS**  trans-74.9121.3172.1520000110.1
660H30.8Very low32.2Very low147 Ų147118.8 Ų118.868%0.68166%0.661SS**  trans-111.6126.7165.6-78.4-69.8000110.2
661I27.5Very low31.7Very low154 Ų154118.6 Ų118.679%0.7967%0.67SS**  trans-85.7109.8170.6-58173.1000106.9V663I661-V663 HydrophobicContact CG2-CG2 3.81Å
662S25.2Very low31.6Very low117 Ų117124.1 Ų124.182%0.81870%0.702SS**  trans-88.1105.3164.2-65.20000108.1M664S662-M664 PolarHBondContact O-N 3.2Å
663V27.8Very low30.9Very low115 Ų115128.5 Ų128.570%0.69771%0.706SS**  trans-82.3107.1168.4-174.60000107.3I661 K665I661-V663 HydrophobicContact CG2-CG2 3.81Å; V663-K665 PolarHBondContact O-N 3.23Å
664M24.5Very low30.4Very low182 Ų182134.3 Ų134.390%0.89773%0.732SS**  trans-72.1111.2159.5-95.5178.4166.600106.9S662 T666S662-M664 PolarHBondContact O-N 3.2Å; M664-T666 PolarHBondContact O-N 2.88Å
665K28.2Very low30.1Very low199 Ų199141.6 Ų141.687%0.86576%0.76SS**  trans-71.8113.4161.7-79.9-175.8174.6-177.40107.2V663V663-K665 PolarHBondContact O-N 3.23Å
666T34.2Very low29.3Very low208 Ų208149 Ų149100%1.27680%0.802SS**  trans-760156.544.50000110M664M664-T666 PolarHBondContact O-N 2.88Å

Retrieved 666 of 666 residues in 885.1 ms (Link to these results)