A0A087XHA8_POEFO Loading...

Monoglyceride lipase

AlphaFold DB , UniProt , Accession A0A087XHA8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 306 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M37.4Very low67.1Low227 Ų227116.7 Ų116.7100%1.11866%0.661SS**  01210-68.4-72.4-81.100106.1
2P46.1Very low69.5Low123 Ų123112.8 Ų112.880%0.79964%0.644SS**  trans-60.5141.4173.2-11.825.4000109.4
3E44Very low71.6Confident161 Ų161110.3 Ų110.375%0.75262%0.623SS**  trans-56.3133.4170.7-76.2-82.7145.400109.5G5E3-G5 PolarHBondContact O-N 3.49Å
4P42.7Very low73.3Confident131 Ų131105 Ų10585%0.85161%0.605SS**THydrogen-bonded Turntrans-70.7101176.812.4-5000109.8
5G57.3Low74.9Confident75 Ų75101.2 Ų101.277%0.77358%0.584SS**THydrogen-bonded Turntrans158.8-20.5173.600000116.6E3E3-G5 PolarHBondContact O-N 3.49Å
6D63Low76.3Confident148 Ų14895.6 Ų95.679%0.79155%0.552SS**PPolyproline II helixtrans-78.8128.3-179.7-77.8-20.7000111.4
7A73.3Confident77.5Confident82 Ų8290.1 Ų90.168%0.67852%0.52SS*.PPolyproline II helixtrans-55.314217200000109.9R9A7-R9 PolarHBondContact O-N 3.04Å
8P85.1Confident78.5Confident80 Ų8090.6 Ų90.652%0.51953%0.53SS..PPolyproline II helixtrans-57.8128.4-179.422.2-31.5000110.1
9R94.7Very high79.5Confident123 Ų12393.4 Ų93.446%0.46454%0.537SS..PPolyproline II helixtrans-60.4137.8177.7-63.9-73-80-107.3-9.4109.6A7 Y17 G28 E85A7-R9 PolarHBondContact O-N 3.04Å; R9-Y17 HydrophobicContact CB-CD2 4.11Å; R9-Y17 PolarHBondContact O-N 3.11Å; R9-G28 PolarHBondContact NH2-O 2.91Å; R9-E85 IonicContact CZ-OE1 2.9Å; R9-E85 IonicContact CZ-OE2 3.1Å; R9-E85 IonicContact NE-OE1 2.77Å; R9-E85 PolarHBondContact NE-OE1 2.81Å; R9-E85 IonicContact NE-OE2 3.37Å; R9-E85 VanDerWaalsContact NH2-CD 3.31Å; R9-E85 IonicContact NH2-OE1 2.83Å; R9-E85 PolarHBondContact NH2-OE1 2.97Å; R9-E85 IonicContact NH2-OE2 3.34Å; R9-E85 PolarHBondContact NH2-OE2 3.46Å
10R97.1Very high80.4Confident128 Ų12890.4 Ų90.448%0.48352%0.519SS..BIsolated β-bridgetrans-127.2150-174.1-72.6171-178-88.5-3.4110.7G14 V15 P16 Y17R10-G14 WeakPolarHBondContact CD-O 3.49Å; R10-G14 PolarHBondContact NH1-O 3.24Å; R10-V15 CarbonylContact C-O 3.47Å; R10-V15 WeakPolarHBondContact CA-O 3.15Å; R10-P16 HydrophobicContact CG-CG 4.45Å; R10-Y17 VanDerWaalsContact O-CE2 3.3Å; R10-Y17 WeakPolarHBondContact O-CE2 3.48Å
11S97.2Very high81.2Confident6 Ų692.7 Ų92.74%0.04252%0.519CS..  trans-60.8163.5168.475.90000110.7Q13 G14 V15 Q83S11-Q13 VanDerWaalsContact CB-OE1 3.32Å; S11-Q13 PolarHBondContact O-N 2.79Å; S11-Q13 PolarHBondContact OG-N 3.49Å; S11-Q13 PolarHBondContact OG-OE1 2.94Å; S11-G14 PolarHBondContact O-N 3.15Å; S11-V15 PolarHBondContact N-O 3.32Å; S11-V15 PolarHBondContact OG-N 3.13Å; S11-Q83 WeakPolarHBondContact CB-O 3.41Å
12P96.6Very high84.2Confident70 Ų7085 Ų8546%0.45548%0.48SS..THydrogen-bonded Turntrans-56.1-22.3173.4-24.834.6000114.3G14 Q83 S84P12-G14 VanDerWaalsContact C-N 3.31Å; P12-Q83 WeakPolarHBondContact CD-O 3.45Å; P12-S84 VanDerWaalsContact CG-O 3.29Å; P12-S84 WeakPolarHBondContact CG-O 3.48Å
13Q96.3Very high86.7Confident80 Ų8079.9 Ų79.937%0.37445%0.446SS..THydrogen-bonded Turntrans-87.72.6176.7-54.173.326.800112.8S11 G82 L200S11-Q13 VanDerWaalsContact CB-OE1 3.32Å; S11-Q13 PolarHBondContact O-N 2.79Å; S11-Q13 PolarHBondContact OG-N 3.49Å; S11-Q13 PolarHBondContact OG-OE1 2.94Å; Q13-G82 PolarHBondContact NE2-O 2.82Å; Q13-L200 VanDerWaalsContact CD-CD2 3.46Å; Q13-L200 HydrophobicContact CG-CD2 3.69Å; Q13-L200 VanDerWaalsContact NE2-CD2 3.27Å
14G96.1Very high89.3Confident36 Ų3675.3 Ų75.337%0.37143%0.429SS..SBendtrans86.86.4176.400000115.2R10 S11 P12R10-G14 WeakPolarHBondContact CD-O 3.49Å; R10-G14 PolarHBondContact NH1-O 3.24Å; S11-G14 PolarHBondContact O-N 3.15Å; P12-G14 VanDerWaalsContact C-N 3.31Å
15V96.5Very high91.9Very high48 Ų4869.3 Ų69.329%0.29139%0.39SS..  trans-84130.3-179.6-175.10000110.3R10 S11 Y17 L20R10-V15 CarbonylContact C-O 3.47Å; R10-V15 WeakPolarHBondContact CA-O 3.15Å; S11-V15 PolarHBondContact N-O 3.32Å; S11-V15 PolarHBondContact OG-N 3.13Å; V15-Y17 PolarHBondContact O-N 2.72Å; V15-L20 HydrophobicContact CB-CD1 4.14Å; V15-L20 HydrophobicContact CG1-CD1 4.01Å; V15-L20 HydrophobicContact CG1-CD2 3.92Å; V15-L20 HydrophobicContact CG1-CG 3.9Å
16P97.3Very high93.8Very high11 Ų1169.3 Ų69.37%0.07138%0.382CS..BIsolated β-bridgetrans-60.3133.6176.8-23.635.4000112.3R10 S18 E19R10-P16 HydrophobicContact CG-CG 4.45Å; P16-S18 WeakPolarHBondContact CB-OG 3.11Å; P16-S18 PolarHBondContact O-N 2.74Å; P16-S18 VanDerWaalsContact O-N 3.15Å; P16-E19 HydrophobicContact CB-CG 4.37Å; P16-E19 WeakPolarHBondContact CG-OE1 3.38Å; P16-E19 WeakPolarHBondContact O-CB 3.46Å; P16-E19 PolarHBondContact O-N 3.38Å
17Y97.4Very high95.5Very high2 Ų265.2 Ų65.21%0.00836%0.361CS..G310 helixtrans-64.3-19.2174.2-79.2-70.3000113R9 R10 V15 E19 L20 H22 H30 Q83 S84 E85R9-Y17 HydrophobicContact CB-CD2 4.11Å; R9-Y17 PolarHBondContact O-N 3.11Å; R10-Y17 VanDerWaalsContact O-CE2 3.3Å; R10-Y17 WeakPolarHBondContact O-CE2 3.48Å; V15-Y17 PolarHBondContact O-N 2.72Å; Y17-E19 PolarHBondContact O-N 2.97Å; Y17-L20 HydrophobicContact CD1-CB 4.38Å; Y17-L20 HydrophobicContact CD1-CD1 4.16Å; Y17-L20 HydrophobicContact CE1-CD1 4.39Å; Y17-L20 PolarHBondContact O-N 3.46Å; Y17-L20 VanDerWaalsContact O-N 3.13Å; Y17-H22 HydrophobicContact CD1-CB 3.82Å; Y17-H22 HydrophobicContact CE1-CB 4.41Å; Y17-H22 PolarHBondContact O-CE1 2.87Å; Y17-H22 PolarHBondContact O-ND1 2.99Å; Y17-H30 HydrophobicContact CD1-CB 3.89Å; Y17-H30 HydrophobicContact CD2-CB 3.53Å; Y17-H30 AromaticContact CD2-CG 3.66Å; Y17-H30 AromaticContact CD2-ND1 3.79Å; Y17-H30 HydrophobicContact CE1-CB 3.73Å; Y17-H30 HydrophobicContact CE2-CB 3.37Å; Y17-H30 AromaticContact CE2-CG 3.98Å; Y17-H30 HydrophobicContact CG-CB 3.77Å; Y17-H30 AromaticContact CG-CG 3.9Å; Y17-H30 AromaticContact CG-ND1 3.64Å; Y17-H30 VanDerWaalsContact CZ-CB 3.45Å; Y17-H30 PolarHBondContact OH-O 3.02Å; Y17-Q83 PolarHBondContact OH-O 2.96Å; Y17-S84 VanDerWaalsContact OH-CA 3.3Å; Y17-S84 WeakPolarHBondContact OH-CA 3.46Å; Y17-E85 HydrophobicContact CE2-CG 3.62Å; Y17-E85 WeakPolarHBondContact OH-CG 3.3Å; Y17-E85 PolarHBondContact OH-N 2.91Å
18S95.8Very high96.7Very high99 Ų9963 Ų6369%0.69235%0.346SS*.G310 helixtrans-62.6-19.3170.452.90000113.8P16P16-S18 WeakPolarHBondContact CB-OG 3.11Å; P16-S18 PolarHBondContact O-N 2.74Å; P16-S18 VanDerWaalsContact O-N 3.15Å
19E96.6Very high97.3Very high144 Ų14461.2 Ų61.267%0.67333%0.332SS*.G310 helixtrans-100.7-6.8177.5-63.1172.4-14900112.2P16 Y17P16-E19 HydrophobicContact CB-CG 4.37Å; P16-E19 WeakPolarHBondContact CG-OE1 3.38Å; P16-E19 WeakPolarHBondContact O-CB 3.46Å; P16-E19 PolarHBondContact O-N 3.38Å; Y17-E19 PolarHBondContact O-N 2.97Å
20L97.6Very high97.5Very high33 Ų3356.8 Ų56.817%0.17332%0.316CS..SBendtrans-112.7146.4-178.1-59176.9000110.6V15 Y17 H22 F32V15-L20 HydrophobicContact CB-CD1 4.14Å; V15-L20 HydrophobicContact CG1-CD1 4.01Å; V15-L20 HydrophobicContact CG1-CD2 3.92Å; V15-L20 HydrophobicContact CG1-CG 3.9Å; Y17-L20 HydrophobicContact CD1-CB 4.38Å; Y17-L20 HydrophobicContact CD1-CD1 4.16Å; Y17-L20 HydrophobicContact CE1-CD1 4.39Å; Y17-L20 PolarHBondContact O-N 3.46Å; Y17-L20 VanDerWaalsContact O-N 3.13Å; L20-H22 PolarHBondContact O-N 2.8Å; L20-H22 PolarHBondContact O-ND1 2.71Å; L20-F32 HydrophobicContact CB-CD2 4.15Å; L20-F32 HydrophobicContact CB-CE2 4.42Å; L20-F32 HydrophobicContact CD1-CD2 4.13Å; L20-F32 HydrophobicContact CD2-CD2 4.43Å; L20-F32 HydrophobicContact CD2-CE2 4.15Å; L20-F32 HydrophobicContact CG-CD2 4.47Å
21R98.2Very high97.6Very high139 Ų13950.7 Ų50.753%0.52529%0.293SS..  trans-68.6126165.1-61.4-174.1-174.7-156.84107.8C33 Y35 E37R21-C33 HydrophobicContact CB-CB 4.38Å; R21-C33 PolarHBondContact O-N 3.2Å; R21-Y35 HydrophobicContact CB-CD2 4.38Å; R21-Y35 HydrophobicContact CB-CE2 4.02Å; R21-Y35 VanDerWaalsContact CD-CD2 3.44Å; R21-E37 IonicContact NH1-OE1 3.6Å; R21-E37 PolarHBondContact NH1-OE1 2.87Å
22H98.6Very high97.6Very high65 Ų6551.2 Ų51.230%0.30130%0.295SS..EExtended strand (participates in β ladder)trans-153.3162.4-177.969.1-81.2000111.9Y17 L20 H30 L31Y17-H22 HydrophobicContact CD1-CB 3.82Å; Y17-H22 HydrophobicContact CE1-CB 4.41Å; Y17-H22 PolarHBondContact O-CE1 2.87Å; Y17-H22 PolarHBondContact O-ND1 2.99Å; L20-H22 PolarHBondContact O-N 2.8Å; L20-H22 PolarHBondContact O-ND1 2.71Å; H22-H30 AromaticContact CD2-CE1 3.82Å; H22-H30 AromaticContact CD2-ND1 3.07Å; H22-H30 PolarHBondContact CD2-ND1 2.96Å; H22-H30 AromaticContact CG-ND1 3.98Å; H22-H30 AromaticContact NE2-CE1 3.53Å; H22-H30 AromaticContact NE2-ND1 3.23Å; H22-H30 PolarHBondContact NE2-ND1 3.09Å; H22-L31 CarbonylContact C-O 3.56Å; H22-L31 WeakPolarHBondContact CA-O 3.44Å; H22-L31 WeakPolarHBondContact CB-O 3.35Å
23I98.6Very high97.7Very high16 Ų1648 Ų488%0.08227%0.274CS..EExtended strand (participates in β ladder)trans-120.7158.916461.9176.3000109.2H30 L31 H104 L107I23-H30 CarbonylContact O-C 3.58Å; I23-H30 WeakPolarHBondContact O-CA 3.48Å; I23-L31 HydrophobicContact CD1-CD1 4.27Å; I23-L31 HydrophobicContact CG1-CB 3.93Å; I23-L31 HydrophobicContact CG1-CD1 4.26Å; I23-L31 HydrophobicContact CG1-CG 4.36Å; I23-L31 PolarHBondContact N-O 3.5Å; I23-L31 PolarHBondContact O-N 3.04Å; I23-H104 HydrophobicContact CD1-CB 3.85Å; I23-L107 HydrophobicContact CG2-CD2 3.64Å
24V98.6Very high97.9Very high65 Ų6547.2 Ų47.239%0.39427%0.267SS..EExtended strand (participates in β ladder)trans-104.6121.6170.3-178.40000107.9L29 Q103V24-L29 CarbonylContact C-O 3.57Å; V24-L29 WeakPolarHBondContact CA-O 3.43Å; V24-Q103 PolarHBondContact O-NE2 3.31Å
25N98.4Very high98Very high6 Ų647.9 Ų47.93%0.03226%0.259CS..  trans-75.2174.2-178.681.1-3.2000112.2D27 G28 L29 L31 V79 R99 D100 Q103N25-D27 PolarHBondContact O-N 3.34Å; N25-D27 VanDerWaalsContact O-N 3.1Å; N25-D27 WeakPolarHBondContact OD1-CA 3.35Å; N25-D27 PolarHBondContact OD1-N 3.4Å; N25-G28 PolarHBondContact O-N 2.82Å; N25-G28 PolarHBondContact OD1-N 3.11Å; N25-L29 PolarHBondContact N-O 3.34Å; N25-L29 WeakPolarHBondContact OD1-CB 3.36Å; N25-L29 PolarHBondContact OD1-N 2.94Å; N25-L29 PolarHBondContact OD1-O 3.12Å; N25-L31 HydrophobicContact CB-CD1 3.99Å; N25-L31 HydrophobicContact CB-CG 4.24Å; N25-V79 WeakPolarHBondContact ND2-CG2 3.3Å; N25-R99 PolarHBondContact ND2-NH2 2.88Å; N25-D100 PolarHBondContact ND2-OD2 3.06Å; N25-Q103 VanDerWaalsContact CA-OE1 3.29Å
26A98Very high98.1Very high74 Ų7446.2 Ų46.261%0.61225%0.247SC*.THydrogen-bonded Turntrans-64.3-14.5-179.100000114.5
27D97.6Very high98.1Very high63 Ų6350.1 Ų50.134%0.33727%0.265SS..THydrogen-bonded Turntrans-94.55.3174.6-61-33.6000112.5N25 R92 R99N25-D27 PolarHBondContact O-N 3.34Å; N25-D27 VanDerWaalsContact O-N 3.1Å; N25-D27 WeakPolarHBondContact OD1-CA 3.35Å; N25-D27 PolarHBondContact OD1-N 3.4Å; D27-R92 IonicContact OD1-NH2 2.73Å; D27-R92 PolarHBondContact OD1-NH2 2.81Å; D27-R92 IonicContact OD2-NH2 3.25Å; D27-R92 PolarHBondContact OD2-NH2 3.1Å; D27-R99 VanDerWaalsContact CG-NH2 3.29Å; D27-R99 IonicContact OD1-CZ 3.23Å; D27-R99 IonicContact OD1-NH1 3.8Å; D27-R99 PolarHBondContact OD1-NH1 2.7Å; D27-R99 IonicContact OD1-NH2 3.11Å; D27-R99 IonicContact OD2-CZ 2.74Å; D27-R99 IonicContact OD2-NH1 3.5Å; D27-R99 PolarHBondContact OD2-NH1 2.9Å; D27-R99 VanDerWaalsContact OD2-NH1 3.1Å; D27-R99 IonicContact OD2-NH2 3.53Å; D27-R99 PolarHBondContact OD2-NH2 3.36Å
28G97.8Very high98.1Very high35 Ų3551 Ų5136%0.36127%0.27SS..SBendtrans77.518.5-179.900000114.4R9 N25R9-G28 PolarHBondContact NH2-O 2.91Å; N25-G28 PolarHBondContact O-N 2.82Å; N25-G28 PolarHBondContact OD1-N 3.11Å
29L98.1Very high98.1Very high43 Ų4351.6 Ų51.623%0.22528%0.282CS..  trans-94.3137.3176.1-59.5179000110.8V24 N25 V79 E85V24-L29 CarbonylContact C-O 3.57Å; V24-L29 WeakPolarHBondContact CA-O 3.43Å; N25-L29 PolarHBondContact N-O 3.34Å; N25-L29 WeakPolarHBondContact OD1-CB 3.36Å; N25-L29 PolarHBondContact OD1-N 2.94Å; N25-L29 PolarHBondContact OD1-O 3.12Å; L29-V79 HydrophobicContact CD1-CG1 3.73Å; L29-V79 HydrophobicContact CD1-CG2 4.18Å; L29-E85 WeakPolarHBondContact CA-OE2 3.13Å; L29-E85 HydrophobicContact CB-CB 4.19Å; L29-E85 HydrophobicContact CD2-CB 4.18Å
30H98.7Very high97.9Very high30 Ų3047.9 Ų47.914%0.13927%0.272CS..EExtended strand (participates in β ladder)trans-78127.1173.5-71.2-111.6000110.4Y17 H22 I23 E85Y17-H30 HydrophobicContact CD1-CB 3.89Å; Y17-H30 HydrophobicContact CD2-CB 3.53Å; Y17-H30 AromaticContact CD2-CG 3.66Å; Y17-H30 AromaticContact CD2-ND1 3.79Å; Y17-H30 HydrophobicContact CE1-CB 3.73Å; Y17-H30 HydrophobicContact CE2-CB 3.37Å; Y17-H30 AromaticContact CE2-CG 3.98Å; Y17-H30 HydrophobicContact CG-CB 3.77Å; Y17-H30 AromaticContact CG-CG 3.9Å; Y17-H30 AromaticContact CG-ND1 3.64Å; Y17-H30 VanDerWaalsContact CZ-CB 3.45Å; Y17-H30 PolarHBondContact OH-O 3.02Å; H22-H30 AromaticContact CD2-CE1 3.82Å; H22-H30 AromaticContact CD2-ND1 3.07Å; H22-H30 PolarHBondContact CD2-ND1 2.96Å; H22-H30 AromaticContact CG-ND1 3.98Å; H22-H30 AromaticContact NE2-CE1 3.53Å; H22-H30 AromaticContact NE2-ND1 3.23Å; H22-H30 PolarHBondContact NE2-ND1 3.09Å; I23-H30 CarbonylContact O-C 3.58Å; I23-H30 WeakPolarHBondContact O-CA 3.48Å; H30-E85 HydrophobicContact CB-CG 4.08Å; H30-E85 IonicContact CD2-OE2 2.79Å; H30-E85 PolarHBondContact N-OE2 3.02Å; H30-E85 PolarHBondContact O-N 3.49Å
31L98.9Very high97.8Very high0 Ų051.7 Ų51.70%030%0.299CS..EExtended strand (participates in β ladder)trans-108.8120.7174-50.3-175.5000109.6H22 I23 N25 C33 H76 V79 S84 D100H22-L31 CarbonylContact C-O 3.56Å; H22-L31 WeakPolarHBondContact CA-O 3.44Å; H22-L31 WeakPolarHBondContact CB-O 3.35Å; I23-L31 HydrophobicContact CD1-CD1 4.27Å; I23-L31 HydrophobicContact CG1-CB 3.93Å; I23-L31 HydrophobicContact CG1-CD1 4.26Å; I23-L31 HydrophobicContact CG1-CG 4.36Å; I23-L31 PolarHBondContact N-O 3.5Å; I23-L31 PolarHBondContact O-N 3.04Å; N25-L31 HydrophobicContact CB-CD1 3.99Å; N25-L31 HydrophobicContact CB-CG 4.24Å; L31-C33 PolarHBondContact O-SG 3.38Å; L31-H76 HydrophobicContact CB-CB 4.39Å; L31-V79 HydrophobicContact CD2-CB 4.48Å; L31-V79 HydrophobicContact CD2-CG2 3.52Å; L31-S84 WeakPolarHBondContact CA-OG 3.42Å; L31-D100 HydrophobicContact CD1-CB 3.88Å
32F98.9Very high97.7Very high17 Ų1745.9 Ų45.98%0.07528%0.279CS..EExtended strand (participates in β ladder)trans-61.3136.8171.9172.7-95.5000110.1L20 R34 H76 D77 Q83 S84L20-F32 HydrophobicContact CB-CD2 4.15Å; L20-F32 HydrophobicContact CB-CE2 4.42Å; L20-F32 HydrophobicContact CD1-CD2 4.13Å; L20-F32 HydrophobicContact CD2-CD2 4.43Å; L20-F32 HydrophobicContact CD2-CE2 4.15Å; L20-F32 HydrophobicContact CG-CD2 4.47Å; F32-R34 HydrophobicContact CE1-CB 4.22Å; F32-H76 CarbonylContact O-C 3.6Å; F32-H76 WeakPolarHBondContact O-CA 3.32Å; F32-H76 WeakPolarHBondContact O-CB 3.29Å; F32-D77 HydrophobicContact CB-CB 4.44Å; F32-D77 WeakPolarHBondContact CD1-OD2 3.44Å; F32-D77 PolarHBondContact O-N 2.84Å; F32-Q83 HydrophobicContact CB-CB 3.63Å; F32-Q83 HydrophobicContact CD1-CB 4.27Å; F32-Q83 HydrophobicContact CD2-CB 4.01Å; F32-Q83 VanDerWaalsContact CE1-NE2 3.35Å; F32-Q83 HydrophobicContact CG-CB 3.7Å; F32-S84 PolarHBondContact N-OG 3.36Å
33C98.9Very high97.6Very high2 Ų247.1 Ų47.11%0.01428%0.281CS..EExtended strand (participates in β ladder)trans-122.1143.9-179.4-61.30000111.7R21 L31 Y35 A75R21-C33 HydrophobicContact CB-CB 4.38Å; R21-C33 PolarHBondContact O-N 3.2Å; L31-C33 PolarHBondContact O-SG 3.38Å; C33-Y35 HydrophobicContact CB-CD2 4.37Å; C33-Y35 HydrophobicContact CB-CE2 3.46Å; C33-Y35 VanDerWaalsContact CB-CE2 3.46Å; C33-A75 CarbonylContact C-O 3.22Å; C33-A75 WeakPolarHBondContact CA-O 3.41Å
34R98.8Very high97.6Very high64 Ų6446.3 Ų46.324%0.24228%0.277CS..EExtended strand (participates in β ladder)trans-123.9139.8175.9-165.4174.4-68.6-94.64109.4F32 W36 S56 F74 A75F32-R34 HydrophobicContact CE1-CB 4.22Å; R34-W36 HydrophobicContact CB-CH2 4Å; R34-W36 HydrophobicContact CB-CZ3 4.03Å; R34-W36 HydrophobicContact CG-CD2 4.29Å; R34-W36 HydrophobicContact CG-CE3 4.2Å; R34-W36 HydrophobicContact CG-CH2 3.51Å; R34-W36 HydrophobicContact CG-CZ2 3.56Å; R34-W36 HydrophobicContact CG-CZ3 3.81Å; R34-S56 PolarHBondContact NE-OG 3.42Å; R34-F74 CarbonylContact O-C 2.9Å; R34-F74 VanDerWaalsContact O-CA 3.29Å; R34-F74 WeakPolarHBondContact O-CA 3.43Å; R34-A75 PolarHBondContact N-O 2.83Å; R34-A75 PolarHBondContact O-N 3.11Å
35Y98.7Very high97.7Very high49 Ų4943.3 Ų43.319%0.19226%0.258CS..EExtended strand (participates in β ladder)trans-139134.4-178.2-55.9-92.5000110R21 C33 V73 F74 H104 M108R21-Y35 HydrophobicContact CB-CD2 4.38Å; R21-Y35 HydrophobicContact CB-CE2 4.02Å; R21-Y35 VanDerWaalsContact CD-CD2 3.44Å; C33-Y35 HydrophobicContact CB-CD2 4.37Å; C33-Y35 HydrophobicContact CB-CE2 3.46Å; C33-Y35 VanDerWaalsContact CB-CE2 3.46Å; Y35-V73 WeakPolarHBondContact CA-O 3.37Å; Y35-F74 HydrophobicContact CD1-CB 3.53Å; Y35-F74 HydrophobicContact CE1-CB 3.84Å; Y35-F74 HydrophobicContact CG-CB 4.46Å; Y35-H104 AromaticContact CE1-NE2 3.62Å; Y35-H104 AromaticContact CZ-NE2 3.57Å; Y35-H104 PolarHBondContact OH-NE2 2.86Å; Y35-M108 HydrophobicContact CD1-CE 4.2Å; Y35-M108 HydrophobicContact CD1-SD 4.34Å; Y35-M108 HydrophobicContact CE1-CE 4.1Å; Y35-M108 HydrophobicContact CE1-SD 3.64Å
36W98.7Very high97.7Very high13 Ų1343 Ų435%0.04926%0.257CS..EExtended strand (participates in β ladder)trans-118.794.3173.1-57.2-101.1000107.8R34 E60 A63 K67 V73 A75R34-W36 HydrophobicContact CB-CH2 4Å; R34-W36 HydrophobicContact CB-CZ3 4.03Å; R34-W36 HydrophobicContact CG-CD2 4.29Å; R34-W36 HydrophobicContact CG-CE3 4.2Å; R34-W36 HydrophobicContact CG-CH2 3.51Å; R34-W36 HydrophobicContact CG-CZ2 3.56Å; R34-W36 HydrophobicContact CG-CZ3 3.81Å; W36-E60 VanDerWaalsContact NE1-CD 3.26Å; W36-E60 PolarHBondContact NE1-OE1 2.96Å; W36-E60 PolarHBondContact NE1-OE2 3.18Å; W36-A63 HydrophobicContact CB-CB 4.3Å; W36-A63 HydrophobicContact CD2-CB 3.31Å; W36-A63 HydrophobicContact CE3-CB 3.67Å; W36-A63 HydrophobicContact CG-CB 3.64Å; W36-A63 HydrophobicContact CH2-CB 3.95Å; W36-A63 HydrophobicContact CZ2-CB 3.66Å; W36-A63 HydrophobicContact CZ3-CB 3.99Å; W36-K67 HydrophobicContact CB-CB 4.41Å; W36-K67 HydrophobicContact CB-CD 4.08Å; W36-K67 HydrophobicContact CB-CG 4.47Å; W36-V73 HydrophobicContact CB-CB 4.2Å; W36-V73 HydrophobicContact CE3-CB 3.96Å; W36-V73 HydrophobicContact CE3-CG1 3.82Å; W36-V73 HydrophobicContact CZ3-CG1 4.07Å; W36-V73 PolarHBondContact N-O 3.4Å; W36-V73 PolarHBondContact O-N 3.36Å; W36-A75 HydrophobicContact CH2-CB 4.35Å; W36-A75 HydrophobicContact CZ3-CB 4.02Å
37E97.9Very high97.7Very high94 Ų9439.5 Ų39.544%0.43923%0.228SC..  trans-87.8128.6-175.4-67.2-180-131.500110.4R21 K67 L72 R112R21-E37 IonicContact NH1-OE1 3.6Å; R21-E37 PolarHBondContact NH1-OE1 2.87Å; E37-K67 WeakPolarHBondContact O-CD 3.23Å; E37-L72 HydrophobicContact CG-CD1 4.38Å; E37-L72 HydrophobicContact CG-CG 4.3Å; E37-R112 IonicContact OE2-NH2 2.97Å
38P97.4Very high97.8Very high19 Ų1936.6 Ų36.612%0.12321%0.212CC..  trans-72.3153.7176.129.6-34000110.9S40 P42 K67 L71P38-S40 VanDerWaalsContact C-N 3.28Å; P38-S40 WeakPolarHBondContact CG-O 3.38Å; P38-S40 PolarHBondContact O-N 3.36Å; P38-P42 HydrophobicContact CG-CB 3.98Å; P38-K67 HydrophobicContact CB-CG 4.19Å; P38-L71 WeakPolarHBondContact CD-O 3.49Å
39A94.6Very high97.9Very high113 Ų11334.9 Ų34.993%0.93420%0.195SC*.SBendtrans-69.1-28.2175.700000112.7
40S92.7Very high97.9Very high65 Ų6532.9 Ų32.946%0.45518%0.184SC..SBendtrans-94.9159.7175.3-570000111.2P38P38-S40 VanDerWaalsContact C-N 3.28Å; P38-S40 WeakPolarHBondContact CG-O 3.38Å; P38-S40 PolarHBondContact O-N 3.36Å
41P95Very high97.8Very high114 Ų11431.5 Ų31.574%0.7418%0.178SC*.PPolyproline II helixtrans-51.5129.3172.8-26.935.4000111.3
42P97.1Very high97.7Very high16 Ų1632.5 Ų32.510%0.10419%0.186CC..PPolyproline II helixtrans-69.6141.7-175.127.6-34.5000111.4P38 S70 L72 L115P38-P42 HydrophobicContact CG-CB 3.98Å; P42-S70 CarbonylContact C-O 3.56Å; P42-S70 VanDerWaalsContact CA-O 3.24Å; P42-S70 WeakPolarHBondContact CA-O 3.42Å; P42-L72 HydrophobicContact CB-CB 3.79Å; P42-L72 HydrophobicContact CG-CB 4.21Å; P42-L72 HydrophobicContact CG-CD1 4.49Å; P42-L115 HydrophobicContact CB-CD1 4.2Å; P42-L115 HydrophobicContact CG-CD1 3.86Å; P42-L115 WeakPolarHBondContact O-CD2 3.41Å
43R97.6Very high97.5Very high91 Ų9131.9 Ų31.934%0.34318%0.184SC..SBendtrans-90.7-20.2178.1-62.2175.962.1-160-1.6112.8S70 P116 L295 P296R43-S70 PolarHBondContact N-O 2.9Å; R43-P116 WeakPolarHBondContact O-CD 3.43Å; R43-L295 HydrophobicContact CB-CD1 4.49Å; R43-L295 HydrophobicContact CB-CD2 4.45Å; R43-P296 PolarHBondContact NH2-O 3.07Å; R43-P296 VanDerWaalsContact NH2-O 3.11Å
44A98.6Very high97.3Very high0 Ų032.5 Ų32.50%019%0.187CC..  trans-159.3165.2176.400000110.5L71 L72 P116 F118 L295A44-L71 HydrophobicContact CB-CD2 4.44Å; A44-L71 HydrophobicContact CB-CG 4.22Å; A44-L72 PolarHBondContact O-N 3.18Å; A44-P116 WeakPolarHBondContact CA-O 3.06Å; A44-P116 HydrophobicContact CB-CB 3.97Å; A44-P116 HydrophobicContact CB-CG 4.4Å; A44-P116 WeakPolarHBondContact CB-O 3.33Å; A44-F118 HydrophobicContact CB-CD2 4.01Å; A44-F118 HydrophobicContact CB-CE2 3.89Å; A44-L295 HydrophobicContact CB-CD2 3.54Å
45L98.8Very high97.3Very high1 Ų129.8 Ų29.81%0.00518%0.177CC..EExtended strand (participates in β ladder)trans-102139.6168.8-58.4-179000109.3L72 F74 M108 K109 R112 L115 P116 V117 F118L45-L72 CarbonylContact C-O 3.17Å; L45-L72 WeakPolarHBondContact CA-O 3.45Å; L45-L72 HydrophobicContact CD2-CB 3.96Å; L45-L72 HydrophobicContact CD2-CD1 4.27Å; L45-L72 HydrophobicContact CD2-CD2 4.31Å; L45-L72 HydrophobicContact CD2-CG 4.41Å; L45-F74 HydrophobicContact CB-CE1 3.97Å; L45-M108 HydrophobicContact CD1-CB 3.97Å; L45-K109 HydrophobicContact CD1-CG 4.27Å; L45-R112 HydrophobicContact CD1-CB 4.36Å; L45-R112 HydrophobicContact CD2-CB 4.1Å; L45-R112 HydrophobicContact CD2-CG 4.14Å; L45-L115 HydrophobicContact CD2-CD1 4.05Å; L45-L115 HydrophobicContact CG-CB 4.17Å; L45-L115 HydrophobicContact CG-CD1 4.22Å; L45-P116 PolarHBondContact N-O 3.07Å; L45-V117 HydrophobicContact CB-CG2 4.35Å; L45-V117 HydrophobicContact CD1-CG2 4.29Å; L45-V117 WeakPolarHBondContact O-CA 3.13Å; L45-F118 PolarHBondContact O-N 2.9Å
46V98.9Very high97.3Very high0 Ų027.5 Ų27.50%017%0.168CC..EExtended strand (participates in β ladder)trans-128.9114.1174.2-1710000109.8L66 L71 L72 V73 F74 F118 V120V46-L66 HydrophobicContact CB-CD1 4.43Å; V46-L66 HydrophobicContact CG1-CD1 3.98Å; V46-L66 HydrophobicContact CG2-CD1 4.34Å; V46-L71 HydrophobicContact CG2-CB 4.11Å; V46-L71 HydrophobicContact CG2-CD2 3.6Å; V46-L71 HydrophobicContact CG2-CG 4.38Å; V46-L72 PolarHBondContact N-O 2.9Å; V46-V73 HydrophobicContact CB-CG1 4.44Å; V46-V73 HydrophobicContact CB-CG2 4.32Å; V46-V73 WeakPolarHBondContact O-CA 3.39Å; V46-F74 VanDerWaalsContact O-CD1 3.24Å; V46-F74 WeakPolarHBondContact O-CD1 3.37Å; V46-F74 PolarHBondContact O-N 2.74Å; V46-F118 WeakPolarHBondContact CA-O 3.49Å; V46-F118 HydrophobicContact CG1-CB 4.32Å; V46-F118 HydrophobicContact CG2-CB 4.27Å; V46-V120 HydrophobicContact CG1-CG2 3.7Å
47F98.9Very high97.3Very high1 Ų127.7 Ų27.70%0.00417%0.174CC..EExtended strand (participates in β ladder)trans-85.9129171.2-178-117.6000109.9A49 F74 H76 S101 H104 I105 F118 I119 V120F47-A49 HydrophobicContact CD1-CB 4.4Å; F47-A49 HydrophobicContact CE1-CB 3.9Å; F47-F74 CarbonylContact C-O 3.51Å; F47-F74 WeakPolarHBondContact CA-O 3.47Å; F47-F74 HydrophobicContact CB-CE1 4.04Å; F47-F74 HydrophobicContact CB-CE2 4.02Å; F47-F74 HydrophobicContact CB-CZ 3.66Å; F47-F74 AromaticContact CD2-CD2 3.76Å; F47-F74 HydrophobicContact CD2-CD2 3.76Å; F47-F74 AromaticContact CD2-CE2 3.49Å; F47-F74 HydrophobicContact CD2-CE2 3.49Å; F47-F74 VanDerWaalsContact CD2-CE2 3.49Å; F47-F74 HydrophobicContact CD2-CZ 4.06Å; F47-F74 HydrophobicContact CE2-CE2 4.38Å; F47-F74 HydrophobicContact CG-CE2 4.13Å; F47-F74 HydrophobicContact CG-CZ 4.27Å; F47-H76 AromaticContact CE2-CE1 3.98Å; F47-H76 AromaticContact CE2-ND1 3.86Å; F47-H76 AromaticContact CZ-CE1 3.61Å; F47-H76 AromaticContact CZ-ND1 3.96Å; F47-H76 AromaticContact CZ-NE2 3.95Å; F47-S101 WeakPolarHBondContact CE1-OG 3.49Å; F47-H104 AromaticContact CE2-ND1 3.94Å; F47-I105 HydrophobicContact CB-CD1 4.26Å; F47-I105 HydrophobicContact CB-CG1 4.05Å; F47-I105 HydrophobicContact CD1-CD1 4.04Å; F47-I105 HydrophobicContact CD1-CG1 4.43Å; F47-I105 HydrophobicContact CG-CD1 4.18Å; F47-I105 HydrophobicContact CG-CG1 4.09Å; F47-F118 PolarHBondContact N-O 3.37Å; F47-I119 HydrophobicContact CD1-CG2 3.98Å; F47-I119 CarbonylContact O-C 3.5Å; F47-I119 WeakPolarHBondContact O-CA 3.34Å; F47-V120 PolarHBondContact O-N 3.36Å
48I98.9Very high97.2Very high1 Ų124.7 Ų24.71%0.00516%0.163CC..EExtended strand (participates in β ladder)trans-103.2123.4171.9-62.3-173.4000109.4Y59 I62 A63 V73 F74 A75 V120I48-Y59 HydrophobicContact CG2-CD1 3.33Å; I48-Y59 HydrophobicContact CG2-CD2 4.1Å; I48-Y59 HydrophobicContact CG2-CE1 3.87Å; I48-Y59 HydrophobicContact CG2-CG 3.47Å; I48-Y59 VanDerWaalsContact CG2-CG 3.47Å; I48-I62 HydrophobicContact CD1-CG2 4.05Å; I48-A63 HydrophobicContact CD1-CB 4.2Å; I48-V73 HydrophobicContact CD1-CG1 3.47Å; I48-V73 VanDerWaalsContact CD1-CG1 3.47Å; I48-V73 HydrophobicContact CG1-CG1 3.72Å; I48-F74 PolarHBondContact N-O 2.86Å; I48-A75 HydrophobicContact CB-CB 4.14Å; I48-V120 CarbonylContact C-O 3.3Å; I48-V120 WeakPolarHBondContact CA-O 3.4Å; I48-V120 HydrophobicContact CG1-CB 4.31Å
49A98.9Very high97.3Very high0 Ų023.8 Ų23.80%016%0.157CC..EExtended strand (participates in β ladder)trans-108.7117.5175.600000110F47 V120 G121 H122 G125F47-A49 HydrophobicContact CD1-CB 4.4Å; F47-A49 HydrophobicContact CE1-CB 3.9Å; A49-V120 PolarHBondContact N-O 2.91Å; A49-G121 WeakPolarHBondContact O-CA 3.32Å; A49-H122 PolarHBondContact O-N 2.89Å; A49-G125 WeakPolarHBondContact O-CA 3.48Å
50H98.8Very high97.4Very high1 Ų121.9 Ų21.91%0.00513%0.129CC..  trans-86.7162-174.872.376.1000112.7E54 H55 Y59 H76 D77 H78 H81 G125H50-E54 HydrophobicContact CB-CG 4.19Å; H50-E54 PolarHBondContact CE1-O 2.97Å; H50-E54 PolarHBondContact ND1-O 2.67Å; H50-H55 WeakPolarHBondContact CB-O 3.34Å; H50-Y59 WeakPolarHBondContact CA-OH 3.32Å; H50-Y59 HydrophobicContact CB-CD2 4.22Å; H50-Y59 HydrophobicContact CB-CE2 3.42Å; H50-Y59 VanDerWaalsContact CB-CE2 3.42Å; H50-H76 PolarHBondContact CD2-O 2.86Å; H50-D77 WeakPolarHBondContact NE2-CA 3.2Å; H50-H78 AromaticContact CD2-CD2 3.62Å; H50-H78 AromaticContact CE1-CD2 3.46Å; H50-H78 PolarHBondContact CE1-CD2 3.49Å; H50-H78 VanDerWaalsContact CE1-CD2 3.46Å; H50-H78 AromaticContact CE1-CG 3.95Å; H50-H78 AromaticContact CG-CD2 3.85Å; H50-H78 PolarHBondContact N-NE2 3.11Å; H50-H78 AromaticContact ND1-CD2 3.75Å; H50-H78 AromaticContact NE2-CD2 3.38Å; H50-H78 PolarHBondContact NE2-CD2 3.2Å; H50-H78 AromaticContact NE2-CG 3.61Å; H50-H78 PolarHBondContact NE2-N 2.97Å; H50-H78 PolarHBondContact O-CD2 3.16Å; H50-H78 PolarHBondContact O-NE2 3.37Å; H50-H81 AromaticContact CE1-CD2 3.71Å; H50-H81 AromaticContact CE1-CG 3.66Å; H50-G125 WeakPolarHBondContact O-CA 3.5Å; H50-G125 PolarHBondContact O-N 3.28Å; H50-G125 VanDerWaalsContact O-N 3.13Å
51G97.4Very high97.7Very high1 Ų123.1 Ų23.11%0.0113%0.127CC..  trans-72175.5177.800000114.5E54G51-E54 WeakPolarHBondContact CA-OE1 3.5Å; G51-E54 PolarHBondContact N-OE1 2.73Å; G51-E54 VanDerWaalsContact O-CG 3.26Å; G51-E54 WeakPolarHBondContact O-CG 3.38Å
52A96.1Very high97.8Very high21 Ų2117.9 Ų17.917%0.1749%0.093CC..THydrogen-bonded Turntrans-72.6134.1-179.800000110.6E54 M89 M124 F210A52-E54 PolarHBondContact O-N 2.97Å; A52-M89 HydrophobicContact CB-CE 3.98Å; A52-M89 HydrophobicContact CB-SD 4.17Å; A52-M124 HydrophobicContact CB-CB 3.92Å; A52-M124 HydrophobicContact CB-CE 4.18Å; A52-M124 HydrophobicContact CB-CG 4.4Å; A52-M124 HydrophobicContact CB-SD 3.71Å; A52-F210 HydrophobicContact CB-CE1 4.16Å; A52-F210 HydrophobicContact CB-CZ 4.45Å
53G93.9Very high97.9Very high3 Ų317.1 Ų17.13%0.0319%0.088CC..THydrogen-bonded Turntrans78.5-3.1176.400000115H81 M89 N201 Y202G53-H81 PolarHBondContact N-CD2 2.97Å; G53-H81 VanDerWaalsContact N-CD2 3.25Å; G53-H81 PolarHBondContact N-NE2 3.26Å; G53-H81 VanDerWaalsContact N-NE2 3.12Å; G53-M89 VanDerWaalsContact CA-SD 3.58Å; G53-M89 PolarHBondContact N-SD 3.19Å; G53-N201 CarbonylContact O-C 3.51Å; G53-N201 VanDerWaalsContact O-CA 3.29Å; G53-N201 WeakPolarHBondContact O-CA 3.37Å; G53-Y202 PolarHBondContact O-N 2.75Å
54E95.9Very high98Very high16 Ų1615.4 Ų15.48%0.0758%0.084CC..  trans-106.3-162.4170.859.6173.8-151.400111.5H50 G51 A52 Y59 H81 H122 N201H50-E54 HydrophobicContact CB-CG 4.19Å; H50-E54 PolarHBondContact CE1-O 2.97Å; H50-E54 PolarHBondContact ND1-O 2.67Å; G51-E54 WeakPolarHBondContact CA-OE1 3.5Å; G51-E54 PolarHBondContact N-OE1 2.73Å; G51-E54 VanDerWaalsContact O-CG 3.26Å; G51-E54 WeakPolarHBondContact O-CG 3.38Å; A52-E54 PolarHBondContact O-N 2.97Å; E54-Y59 VanDerWaalsContact OE1-CE2 3.28Å; E54-Y59 WeakPolarHBondContact OE1-CE2 3.46Å; E54-Y59 VanDerWaalsContact OE1-CZ 3.29Å; E54-Y59 PolarHBondContact OE1-OH 2.97Å; E54-H81 PolarHBondContact O-CD2 3.11Å; E54-H122 IonicContact OE1-CD2 3.42Å; E54-N201 WeakPolarHBondContact CA-OD1 3.43Å
55H98.6Very high98Very high7 Ų718 Ų183%0.0329%0.094CC..  trans-147.7-174.7-179.263.599.6000111.3H50 G57 P58 D198 L200 N201H50-H55 WeakPolarHBondContact CB-O 3.34Å; H55-G57 VanDerWaalsContact C-N 3.31Å; H55-G57 WeakPolarHBondContact ND1-CA 3.18Å; H55-G57 PolarHBondContact ND1-N 2.9Å; H55-G57 PolarHBondContact O-N 3.27Å; H55-P58 VanDerWaalsContact O-CD 3.28Å; H55-P58 WeakPolarHBondContact O-CD 3.43Å; H55-D198 IonicContact CD2-OD2 2.93Å; H55-D198 IonicContact CE1-OD2 2.75Å; H55-D198 IonicContact NE2-OD1 3.74Å; H55-D198 PolarHBondContact NE2-OD1 3.44Å; H55-D198 IonicContact NE2-OD2 3.91Å; H55-D198 PolarHBondContact NE2-OD2 3.46Å; H55-L200 VanDerWaalsContact CD2-CB 3.41Å; H55-L200 WeakPolarHBondContact CD2-CB 3.17Å; H55-L200 WeakPolarHBondContact NE2-CB 3.47Å; H55-N201 PolarHBondContact CD2-OD1 3.4Å
56S98.6Very high98Very high1 Ų118 Ų181%0.0079%0.094CC..SBendtrans-72.6-17.4-178.260.70000115R34 Y59 D77R34-S56 PolarHBondContact NE-OG 3.42Å; S56-Y59 PolarHBondContact O-N 2.97Å; S56-D77 WeakPolarHBondContact CB-OD1 3.45Å; S56-D77 PolarHBondContact N-OD1 3.5Å; S56-D77 PolarHBondContact OG-OD1 3.39Å
57G98.1Very high97.9Very high16 Ų1621 Ų2117%0.16511%0.107CC..G310 helixtrans-63.2-45.4-174.200000115.8H55 Y59 E60H55-G57 VanDerWaalsContact C-N 3.31Å; H55-G57 WeakPolarHBondContact ND1-CA 3.18Å; H55-G57 PolarHBondContact ND1-N 2.9Å; H55-G57 PolarHBondContact O-N 3.27Å; G57-Y59 PolarHBondContact O-N 2.67Å; G57-E60 PolarHBondContact O-N 3.24Å
58P96.9Very high97.9Very high32 Ų3227.3 Ų27.321%0.20814%0.136CC..G310 helixtrans-59.6-14.6-179.7-26.437000114.2H55 E60 H274H55-P58 VanDerWaalsContact O-CD 3.28Å; H55-P58 WeakPolarHBondContact O-CD 3.43Å; P58-E60 PolarHBondContact O-N 3.39Å; P58-H274 PolarHBondContact O-CE1 3.01Å; P58-H274 PolarHBondContact O-NE2 3.33Å
59Y98.4Very high97.8Very high0 Ų033.5 Ų33.50%016%0.16CC..G310 helixtrans-84.59.6-179.2-65.3-96000114.4I48 H50 E54 S56 G57 E61 I62 A63 H122I48-Y59 HydrophobicContact CG2-CD1 3.33Å; I48-Y59 HydrophobicContact CG2-CD2 4.1Å; I48-Y59 HydrophobicContact CG2-CE1 3.87Å; I48-Y59 HydrophobicContact CG2-CG 3.47Å; I48-Y59 VanDerWaalsContact CG2-CG 3.47Å; H50-Y59 WeakPolarHBondContact CA-OH 3.32Å; H50-Y59 HydrophobicContact CB-CD2 4.22Å; H50-Y59 HydrophobicContact CB-CE2 3.42Å; H50-Y59 VanDerWaalsContact CB-CE2 3.42Å; E54-Y59 VanDerWaalsContact OE1-CE2 3.28Å; E54-Y59 WeakPolarHBondContact OE1-CE2 3.46Å; E54-Y59 VanDerWaalsContact OE1-CZ 3.29Å; E54-Y59 PolarHBondContact OE1-OH 2.97Å; S56-Y59 PolarHBondContact O-N 2.97Å; G57-Y59 PolarHBondContact O-N 2.67Å; Y59-E61 VanDerWaalsContact C-N 3.3Å; Y59-E61 PolarHBondContact O-N 2.93Å; Y59-I62 HydrophobicContact CD1-CD1 4.04Å; Y59-I62 PolarHBondContact O-N 3.39Å; Y59-A63 WeakPolarHBondContact O-CB 3.37Å; Y59-A63 PolarHBondContact O-N 3.3Å; Y59-H122 HydrophobicContact CE1-CB 4.23Å; Y59-H122 VanDerWaalsContact OH-CB 3.28Å; Y59-H122 WeakPolarHBondContact OH-CB 3.13Å; Y59-H122 PolarHBondContact OH-CD2 3.43Å
60E98.2Very high97.7Very high73 Ų7334.8 Ų34.834%0.34117%0.169SC..Hα-helixtrans-51.5-45.5-177.7-174.563.6-149.600112.5W36 G57 P58 A63 Q64W36-E60 VanDerWaalsContact NE1-CD 3.26Å; W36-E60 PolarHBondContact NE1-OE1 2.96Å; W36-E60 PolarHBondContact NE1-OE2 3.18Å; G57-E60 PolarHBondContact O-N 3.24Å; P58-E60 PolarHBondContact O-N 3.39Å; E60-A63 PolarHBondContact O-N 3.45Å; E60-Q64 HydrophobicContact CG-CG 4.39Å; E60-Q64 VanDerWaalsContact O-CG 3.29Å; E60-Q64 WeakPolarHBondContact O-CG 3.47Å; E60-Q64 PolarHBondContact O-N 3.41Å; E60-Q64 WeakPolarHBondContact OE1-CG 3.29Å; E60-Q64 PolarHBondContact OE1-NE2 3Å
61E97.8Very high97.7Very high91 Ų9134.8 Ų34.843%0.42517%0.168SC..Hα-helixtrans-68.8-43.8-176.4-168.5173.517400112.7Y59 A63 Q64 R65 L284Y59-E61 VanDerWaalsContact C-N 3.3Å; Y59-E61 PolarHBondContact O-N 2.93Å; E61-A63 VanDerWaalsContact C-N 3.28Å; E61-A63 PolarHBondContact O-N 2.89Å; E61-Q64 PolarHBondContact O-N 3.36Å; E61-R65 WeakPolarHBondContact O-CG 3.48Å; E61-R65 PolarHBondContact O-N 3.47Å; E61-R65 VanDerWaalsContact O-N 3.13Å; E61-R65 IonicContact OE1-CZ 2.65Å; E61-R65 IonicContact OE1-NE 3.28Å; E61-R65 PolarHBondContact OE1-NE 3.47Å; E61-R65 IonicContact OE1-NH2 3.11Å; E61-R65 PolarHBondContact OE1-NH2 3.39Å; E61-L284 HydrophobicContact CB-CD2 4.41Å; E61-L284 HydrophobicContact CG-CD1 3.84Å; E61-L284 HydrophobicContact CG-CD2 4.14Å; E61-L284 WeakPolarHBondContact OE1-CD1 3.48Å
62I98.3Very high97.8Very high4 Ų434.8 Ų34.82%0.02117%0.168CC..Hα-helixtrans-56.9-47.8172.5-68.4170.6000109.2I48 Y59 R65 L66 I146 H273 L284 V287I48-I62 HydrophobicContact CD1-CG2 4.05Å; Y59-I62 HydrophobicContact CD1-CD1 4.04Å; Y59-I62 PolarHBondContact O-N 3.39Å; I62-R65 PolarHBondContact O-N 2.81Å; I62-L66 HydrophobicContact CG2-CD1 3.85Å; I62-L66 HydrophobicContact CG2-CG 4.5Å; I62-L66 VanDerWaalsContact O-CG 3.32Å; I62-L66 WeakPolarHBondContact O-CG 3.3Å; I62-L66 PolarHBondContact O-N 2.85Å; I62-L66 VanDerWaalsContact O-N 3.13Å; I62-I146 HydrophobicContact CD1-CD1 4.01Å; I62-H273 HydrophobicContact CD1-CB 4.03Å; I62-L284 HydrophobicContact CB-CD2 4.23Å; I62-L284 HydrophobicContact CG1-CD2 3.38Å; I62-V287 HydrophobicContact CG2-CG1 4.33Å
63A98.8Very high97.9Very high0 Ų033.8 Ų33.80%016%0.16CC..Hα-helixtrans-65.4-41.6-175.700000112.7W36 I48 Y59 E60 E61 L66 K67 V73W36-A63 HydrophobicContact CB-CB 4.3Å; W36-A63 HydrophobicContact CD2-CB 3.31Å; W36-A63 HydrophobicContact CE3-CB 3.67Å; W36-A63 HydrophobicContact CG-CB 3.64Å; W36-A63 HydrophobicContact CH2-CB 3.95Å; W36-A63 HydrophobicContact CZ2-CB 3.66Å; W36-A63 HydrophobicContact CZ3-CB 3.99Å; I48-A63 HydrophobicContact CD1-CB 4.2Å; Y59-A63 WeakPolarHBondContact O-CB 3.37Å; Y59-A63 PolarHBondContact O-N 3.3Å; E60-A63 PolarHBondContact O-N 3.45Å; E61-A63 VanDerWaalsContact C-N 3.28Å; E61-A63 PolarHBondContact O-N 2.89Å; A63-L66 PolarHBondContact O-N 3.44Å; A63-K67 VanDerWaalsContact O-CB 3.26Å; A63-K67 WeakPolarHBondContact O-CB 3.36Å; A63-K67 PolarHBondContact O-N 2.9Å; A63-V73 HydrophobicContact CB-CB 4.2Å; A63-V73 HydrophobicContact CB-CG1 3.83Å; A63-V73 HydrophobicContact CB-CG2 4.47Å
64Q98.6Very high98.1Very high55 Ų5533.7 Ų33.726%0.25716%0.159SC..Hα-helixtrans-64.9-43.6177.6-70-66.4-14.500112E60 E61 L66 K67 E68E60-Q64 HydrophobicContact CG-CG 4.39Å; E60-Q64 VanDerWaalsContact O-CG 3.29Å; E60-Q64 WeakPolarHBondContact O-CG 3.47Å; E60-Q64 PolarHBondContact O-N 3.41Å; E60-Q64 WeakPolarHBondContact OE1-CG 3.29Å; E60-Q64 PolarHBondContact OE1-NE2 3Å; E61-Q64 PolarHBondContact O-N 3.36Å; Q64-L66 VanDerWaalsContact C-N 3.32Å; Q64-L66 PolarHBondContact O-N 3.18Å; Q64-K67 WeakPolarHBondContact O-CB 3.47Å; Q64-K67 PolarHBondContact O-N 2.84Å; Q64-E68 WeakPolarHBondContact O-CG 3.23Å; Q64-E68 PolarHBondContact O-N 3.4Å
65R98.4Very high98.3Very high55 Ų5532.9 Ų32.921%0.20816%0.155CC..Hα-helixtrans-61.6-40.8177.4-71.4-176.6-175.5-124.50.6112.4E61 I62 E68 R69 E281E61-R65 WeakPolarHBondContact O-CG 3.48Å; E61-R65 PolarHBondContact O-N 3.47Å; E61-R65 VanDerWaalsContact O-N 3.13Å; E61-R65 IonicContact OE1-CZ 2.65Å; E61-R65 IonicContact OE1-NE 3.28Å; E61-R65 PolarHBondContact OE1-NE 3.47Å; E61-R65 IonicContact OE1-NH2 3.11Å; E61-R65 PolarHBondContact OE1-NH2 3.39Å; I62-R65 PolarHBondContact O-N 2.81Å; R65-E68 PolarHBondContact O-N 3.49Å; R65-R69 WeakPolarHBondContact O-CG 3.43Å; R65-R69 PolarHBondContact O-N 3.36Å; R65-E281 IonicContact CZ-OE1 3.3Å; R65-E281 IonicContact CZ-OE2 2.81Å; R65-E281 IonicContact NH1-OE1 2.72Å; R65-E281 PolarHBondContact NH1-OE1 2.95Å; R65-E281 IonicContact NH1-OE2 3.49Å; R65-E281 PolarHBondContact NH1-OE2 3.12Å; R65-E281 IonicContact NH2-OE1 3.73Å; R65-E281 IonicContact NH2-OE2 3.24Å; R65-E281 PolarHBondContact NH2-OE2 2.88Å
66L98.6Very high98.3Very high0 Ų032.6 Ų32.60%015%0.154CC..Hα-helixtrans-69.9-39.2175.9-65.1174.6000111.4V46 I62 A63 Q64 E68 R69 L71 V73 T288 I291V46-L66 HydrophobicContact CB-CD1 4.43Å; V46-L66 HydrophobicContact CG1-CD1 3.98Å; V46-L66 HydrophobicContact CG2-CD1 4.34Å; I62-L66 HydrophobicContact CG2-CD1 3.85Å; I62-L66 HydrophobicContact CG2-CG 4.5Å; I62-L66 VanDerWaalsContact O-CG 3.32Å; I62-L66 WeakPolarHBondContact O-CG 3.3Å; I62-L66 PolarHBondContact O-N 2.85Å; I62-L66 VanDerWaalsContact O-N 3.13Å; A63-L66 PolarHBondContact O-N 3.44Å; Q64-L66 VanDerWaalsContact C-N 3.32Å; Q64-L66 PolarHBondContact O-N 3.18Å; L66-E68 VanDerWaalsContact C-N 3.3Å; L66-E68 PolarHBondContact O-N 3.15Å; L66-R69 WeakPolarHBondContact O-CA 3.49Å; L66-R69 WeakPolarHBondContact O-CB 3.36Å; L66-R69 PolarHBondContact O-N 3.02Å; L66-L71 HydrophobicContact CB-CB 4.41Å; L66-L71 HydrophobicContact CD2-CD2 4.24Å; L66-L71 WeakPolarHBondContact O-CB 3.45Å; L66-L71 PolarHBondContact O-N 3.36Å; L66-V73 HydrophobicContact CB-CG2 3.61Å; L66-V73 HydrophobicContact CD1-CG2 4.24Å; L66-T288 HydrophobicContact CD2-CG2 4.4Å; L66-I291 HydrophobicContact CD1-CD1 4.11Å; L66-I291 HydrophobicContact CD2-CB 4.41Å; L66-I291 HydrophobicContact CD2-CD1 3.85Å; L66-I291 HydrophobicContact CD2-CG2 4.5Å
67K98.5Very high98.3Very high63 Ų6332.6 Ų32.627%0.27415%0.153SC..Hα-helixtrans-57.6-42.4174.1-171.8-168.8113.2-159.30111.7W36 E37 P38 A63 Q64 R69 S70 L71W36-K67 HydrophobicContact CB-CB 4.41Å; W36-K67 HydrophobicContact CB-CD 4.08Å; W36-K67 HydrophobicContact CB-CG 4.47Å; E37-K67 WeakPolarHBondContact O-CD 3.23Å; P38-K67 HydrophobicContact CB-CG 4.19Å; A63-K67 VanDerWaalsContact O-CB 3.26Å; A63-K67 WeakPolarHBondContact O-CB 3.36Å; A63-K67 PolarHBondContact O-N 2.9Å; Q64-K67 WeakPolarHBondContact O-CB 3.47Å; Q64-K67 PolarHBondContact O-N 2.84Å; K67-R69 PolarHBondContact O-N 3.26Å; K67-S70 WeakPolarHBondContact O-CA 3.44Å; K67-S70 PolarHBondContact O-N 2.76Å; K67-L71 WeakPolarHBondContact CA-O 3.35Å
68E97.6Very high98.3Very high134 Ų13431.8 Ų31.863%0.62615%0.146SC*.Hα-helixtrans-62.2-22.2175.8-73175.6179.200113.4Q64 R65 L66 S70Q64-E68 WeakPolarHBondContact O-CG 3.23Å; Q64-E68 PolarHBondContact O-N 3.4Å; R65-E68 PolarHBondContact O-N 3.49Å; L66-E68 VanDerWaalsContact C-N 3.3Å; L66-E68 PolarHBondContact O-N 3.15Å; E68-S70 PolarHBondContact O-N 3.23Å
69R97.3Very high98.4Very high131 Ų13130.8 Ų30.849%0.49414%0.139SC..THydrogen-bonded Turntrans-88.211.4173.2-57.2-57.3-179.8-146.4-3.2113.3R65 L66 K67 L71 T288 T292R65-R69 WeakPolarHBondContact O-CG 3.43Å; R65-R69 PolarHBondContact O-N 3.36Å; L66-R69 WeakPolarHBondContact O-CA 3.49Å; L66-R69 WeakPolarHBondContact O-CB 3.36Å; L66-R69 PolarHBondContact O-N 3.02Å; K67-R69 PolarHBondContact O-N 3.26Å; R69-L71 VanDerWaalsContact C-CD1 3.45Å; R69-L71 HydrophobicContact CB-CD1 3.59Å; R69-L71 WeakPolarHBondContact O-CD1 3.44Å; R69-T288 HydrophobicContact CG-CG2 3.88Å; R69-T292 HydrophobicContact CB-CG2 3.86Å; R69-T292 HydrophobicContact CG-CG2 3.79Å
70S97.4Very high98.4Very high27 Ų2730.8 Ų30.819%0.18914%0.139CC..THydrogen-bonded Turntrans63.442.8-175.1-54.80000113P42 R43 K67 E68P42-S70 CarbonylContact C-O 3.56Å; P42-S70 VanDerWaalsContact CA-O 3.24Å; P42-S70 WeakPolarHBondContact CA-O 3.42Å; R43-S70 PolarHBondContact N-O 2.9Å; K67-S70 WeakPolarHBondContact O-CA 3.44Å; K67-S70 PolarHBondContact O-N 2.76Å; E68-S70 PolarHBondContact O-N 3.23Å
71L98.5Very high98.4Very high0 Ų027.5 Ų27.50%012%0.124CC..  trans-106.5139.5170.7-7165.2000108.8P38 A44 V46 L66 K67 R69 V73 I291 L295P38-L71 WeakPolarHBondContact CD-O 3.49Å; A44-L71 HydrophobicContact CB-CD2 4.44Å; A44-L71 HydrophobicContact CB-CG 4.22Å; V46-L71 HydrophobicContact CG2-CB 4.11Å; V46-L71 HydrophobicContact CG2-CD2 3.6Å; V46-L71 HydrophobicContact CG2-CG 4.38Å; L66-L71 HydrophobicContact CB-CB 4.41Å; L66-L71 HydrophobicContact CD2-CD2 4.24Å; L66-L71 WeakPolarHBondContact O-CB 3.45Å; L66-L71 PolarHBondContact O-N 3.36Å; K67-L71 WeakPolarHBondContact CA-O 3.35Å; R69-L71 VanDerWaalsContact C-CD1 3.45Å; R69-L71 HydrophobicContact CB-CD1 3.59Å; R69-L71 WeakPolarHBondContact O-CD1 3.44Å; L71-V73 PolarHBondContact O-N 3.25Å; L71-I291 HydrophobicContact CD2-CG2 3.41Å; L71-I291 VanDerWaalsContact CD2-CG2 3.41Å; L71-L295 HydrophobicContact CD1-CD1 3.97Å
72L98.7Very high98.5Very high2 Ų223.4 Ų23.41%0.0111%0.105CC..EExtended strand (participates in β ladder)trans-85.9110.9170.8-170.4166.4000107.7E37 P42 A44 L45 V46 F74 M108 R112E37-L72 HydrophobicContact CG-CD1 4.38Å; E37-L72 HydrophobicContact CG-CG 4.3Å; P42-L72 HydrophobicContact CB-CB 3.79Å; P42-L72 HydrophobicContact CG-CB 4.21Å; P42-L72 HydrophobicContact CG-CD1 4.49Å; A44-L72 PolarHBondContact O-N 3.18Å; L45-L72 CarbonylContact C-O 3.17Å; L45-L72 WeakPolarHBondContact CA-O 3.45Å; L45-L72 HydrophobicContact CD2-CB 3.96Å; L45-L72 HydrophobicContact CD2-CD1 4.27Å; L45-L72 HydrophobicContact CD2-CD2 4.31Å; L45-L72 HydrophobicContact CD2-CG 4.41Å; V46-L72 PolarHBondContact N-O 2.9Å; L72-F74 HydrophobicContact CD2-CB 4.16Å; L72-F74 HydrophobicContact CD2-CD1 4.08Å; L72-F74 HydrophobicContact CD2-CG 4.5Å; L72-M108 HydrophobicContact CD1-CE 3.86Å; L72-M108 HydrophobicContact CD2-CE 3.41Å; L72-M108 VanDerWaalsContact CD2-CE 3.41Å; L72-M108 HydrophobicContact CG-CE 4.32Å; L72-R112 HydrophobicContact CD1-CG 4.5Å
73V98.9Very high98.5Very high0 Ų024.4 Ų24.40%011%0.11CC..EExtended strand (participates in β ladder)trans-95.9137.7176.5-170.20000109Y35 W36 V46 I48 A63 L66 L71Y35-V73 WeakPolarHBondContact CA-O 3.37Å; W36-V73 HydrophobicContact CB-CB 4.2Å; W36-V73 HydrophobicContact CE3-CB 3.96Å; W36-V73 HydrophobicContact CE3-CG1 3.82Å; W36-V73 HydrophobicContact CZ3-CG1 4.07Å; W36-V73 PolarHBondContact N-O 3.4Å; W36-V73 PolarHBondContact O-N 3.36Å; V46-V73 HydrophobicContact CB-CG1 4.44Å; V46-V73 HydrophobicContact CB-CG2 4.32Å; V46-V73 WeakPolarHBondContact O-CA 3.39Å; I48-V73 HydrophobicContact CD1-CG1 3.47Å; I48-V73 VanDerWaalsContact CD1-CG1 3.47Å; I48-V73 HydrophobicContact CG1-CG1 3.72Å; A63-V73 HydrophobicContact CB-CB 4.2Å; A63-V73 HydrophobicContact CB-CG1 3.83Å; A63-V73 HydrophobicContact CB-CG2 4.47Å; L66-V73 HydrophobicContact CB-CG2 3.61Å; L66-V73 HydrophobicContact CD1-CG2 4.24Å; L71-V73 PolarHBondContact O-N 3.25Å
74F98.9Very high98.5Very high0 Ų024.4 Ų24.40%011%0.11CC..EExtended strand (participates in β ladder)trans-145150.5177.666.9-73.3000110.6R34 Y35 L45 V46 F47 I48 L72 H104 I105 M108R34-F74 CarbonylContact O-C 2.9Å; R34-F74 VanDerWaalsContact O-CA 3.29Å; R34-F74 WeakPolarHBondContact O-CA 3.43Å; Y35-F74 HydrophobicContact CD1-CB 3.53Å; Y35-F74 HydrophobicContact CE1-CB 3.84Å; Y35-F74 HydrophobicContact CG-CB 4.46Å; L45-F74 HydrophobicContact CB-CE1 3.97Å; V46-F74 VanDerWaalsContact O-CD1 3.24Å; V46-F74 WeakPolarHBondContact O-CD1 3.37Å; V46-F74 PolarHBondContact O-N 2.74Å; F47-F74 CarbonylContact C-O 3.51Å; F47-F74 WeakPolarHBondContact CA-O 3.47Å; F47-F74 HydrophobicContact CB-CE1 4.04Å; F47-F74 HydrophobicContact CB-CE2 4.02Å; F47-F74 HydrophobicContact CB-CZ 3.66Å; F47-F74 AromaticContact CD2-CD2 3.76Å; F47-F74 HydrophobicContact CD2-CD2 3.76Å; F47-F74 AromaticContact CD2-CE2 3.49Å; F47-F74 HydrophobicContact CD2-CE2 3.49Å; F47-F74 VanDerWaalsContact CD2-CE2 3.49Å; F47-F74 HydrophobicContact CD2-CZ 4.06Å; F47-F74 HydrophobicContact CE2-CE2 4.38Å; F47-F74 HydrophobicContact CG-CE2 4.13Å; F47-F74 HydrophobicContact CG-CZ 4.27Å; I48-F74 PolarHBondContact N-O 2.86Å; L72-F74 HydrophobicContact CD2-CB 4.16Å; L72-F74 HydrophobicContact CD2-CD1 4.08Å; L72-F74 HydrophobicContact CD2-CG 4.5Å; F74-H104 AromaticContact CD2-CD2 3.83Å; F74-H104 AromaticContact CD2-CE1 3.74Å; F74-H104 AromaticContact CD2-CG 3.96Å; F74-H104 AromaticContact CD2-ND1 3.89Å; F74-H104 AromaticContact CD2-NE2 3.68Å; F74-H104 HydrophobicContact CE2-CB 4.48Å; F74-I105 HydrophobicContact CE2-CG1 4.15Å; F74-I105 HydrophobicContact CZ-CG1 3.93Å; F74-M108 HydrophobicContact CD1-CG 4.16Å; F74-M108 HydrophobicContact CD2-CG 3.56Å; F74-M108 HydrophobicContact CE1-CB 4.27Å; F74-M108 HydrophobicContact CE1-CG 4.18Å; F74-M108 HydrophobicContact CE2-CB 4.13Å; F74-M108 HydrophobicContact CE2-CG 3.55Å; F74-M108 HydrophobicContact CG-CG 3.87Å; F74-M108 HydrophobicContact CZ-CB 3.98Å; F74-M108 HydrophobicContact CZ-CG 3.87Å
75A98.9Very high98.5Very high0 Ų022.9 Ų22.90%010%0.103CC..EExtended strand (participates in β ladder)trans-148.4160.6-179.800000109.3C33 R34 W36 I48 H104C33-A75 CarbonylContact C-O 3.22Å; C33-A75 WeakPolarHBondContact CA-O 3.41Å; R34-A75 PolarHBondContact N-O 2.83Å; R34-A75 PolarHBondContact O-N 3.11Å; W36-A75 HydrophobicContact CH2-CB 4.35Å; W36-A75 HydrophobicContact CZ3-CB 4.02Å; I48-A75 HydrophobicContact CB-CB 4.14Å; A75-H104 PolarHBondContact O-CE1 3.35Å
76H98.9Very high98.4Very high1 Ų121.7 Ų21.71%0.00511%0.107CC..EExtended strand (participates in β ladder)trans-127.7156.716059.4-123.6000109.5L31 F32 F47 H50 H78 D100 H104L31-H76 HydrophobicContact CB-CB 4.39Å; F32-H76 CarbonylContact O-C 3.6Å; F32-H76 WeakPolarHBondContact O-CA 3.32Å; F32-H76 WeakPolarHBondContact O-CB 3.29Å; F47-H76 AromaticContact CE2-CE1 3.98Å; F47-H76 AromaticContact CE2-ND1 3.86Å; F47-H76 AromaticContact CZ-CE1 3.61Å; F47-H76 AromaticContact CZ-ND1 3.96Å; F47-H76 AromaticContact CZ-NE2 3.95Å; H50-H76 PolarHBondContact CD2-O 2.86Å; H76-H78 AromaticContact CD2-ND1 3.47Å; H76-H78 PolarHBondContact CD2-ND1 3.17Å; H76-H78 AromaticContact NE2-CE1 3.68Å; H76-H78 AromaticContact NE2-ND1 3.14Å; H76-H78 PolarHBondContact NE2-ND1 2.69Å; H76-H78 VanDerWaalsContact NE2-ND1 3.14Å; H76-D100 PolarHBondContact CE1-O 2.86Å; H76-H104 AromaticContact CG-ND1 3.78Å; H76-H104 AromaticContact ND1-CG 3.75Å; H76-H104 AromaticContact ND1-ND1 3.15Å; H76-H104 PolarHBondContact ND1-ND1 3.34Å; H76-H104 VanDerWaalsContact ND1-ND1 3.15Å
77D98.9Very high98.3Very high0 Ų026.5 Ų26.50%013%0.13CC..PPolyproline II helixtrans-74.5126.8164.4-61.6-8.4000107F32 H50 S56 Q83 S84F32-D77 HydrophobicContact CB-CB 4.44Å; F32-D77 WeakPolarHBondContact CD1-OD2 3.44Å; F32-D77 PolarHBondContact O-N 2.84Å; H50-D77 WeakPolarHBondContact NE2-CA 3.2Å; S56-D77 WeakPolarHBondContact CB-OD1 3.45Å; S56-D77 PolarHBondContact N-OD1 3.5Å; S56-D77 PolarHBondContact OG-OD1 3.39Å; D77-Q83 PolarHBondContact OD2-N 3.49Å; D77-S84 WeakPolarHBondContact CB-OG 3.33Å; D77-S84 WeakPolarHBondContact O-CB 3.26Å; D77-S84 PolarHBondContact O-OG 3.48Å
78H98.9Very high98.2Very high0 Ų026.4 Ų26.40%013%0.128CC..PPolyproline II helixtrans-61.2156179.9-65.5-45.8000110.9H50 H76 G80 H81 Y97 I128H50-H78 AromaticContact CD2-CD2 3.62Å; H50-H78 AromaticContact CE1-CD2 3.46Å; H50-H78 PolarHBondContact CE1-CD2 3.49Å; H50-H78 VanDerWaalsContact CE1-CD2 3.46Å; H50-H78 AromaticContact CE1-CG 3.95Å; H50-H78 AromaticContact CG-CD2 3.85Å; H50-H78 PolarHBondContact N-NE2 3.11Å; H50-H78 AromaticContact ND1-CD2 3.75Å; H50-H78 AromaticContact NE2-CD2 3.38Å; H50-H78 PolarHBondContact NE2-CD2 3.2Å; H50-H78 AromaticContact NE2-CG 3.61Å; H50-H78 PolarHBondContact NE2-N 2.97Å; H50-H78 PolarHBondContact O-CD2 3.16Å; H50-H78 PolarHBondContact O-NE2 3.37Å; H76-H78 AromaticContact CD2-ND1 3.47Å; H76-H78 PolarHBondContact CD2-ND1 3.17Å; H76-H78 AromaticContact NE2-CE1 3.68Å; H76-H78 AromaticContact NE2-ND1 3.14Å; H76-H78 PolarHBondContact NE2-ND1 2.69Å; H76-H78 VanDerWaalsContact NE2-ND1 3.14Å; H78-G80 PolarHBondContact O-N 3.35Å; H78-H81 VanDerWaalsContact O-CB 3.3Å; H78-H81 WeakPolarHBondContact O-CB 3.45Å; H78-H81 PolarHBondContact O-N 3.26Å; H78-Y97 HydrophobicContact CB-CD1 3.75Å; H78-Y97 HydrophobicContact CB-CE1 3.64Å; H78-I128 WeakPolarHBondContact NE2-CD1 3.41Å
79V98.6Very high98Very high10 Ų1020.3 Ų20.36%0.06110%0.1CC..THydrogen-bonded Turntrans-48.9134.4174.21720000109.8N25 L29 L31 H81 I91 I96 Y97 D100N25-V79 WeakPolarHBondContact ND2-CG2 3.3Å; L29-V79 HydrophobicContact CD1-CG1 3.73Å; L29-V79 HydrophobicContact CD1-CG2 4.18Å; L31-V79 HydrophobicContact CD2-CB 4.48Å; L31-V79 HydrophobicContact CD2-CG2 3.52Å; V79-H81 VanDerWaalsContact C-N 3.29Å; V79-H81 PolarHBondContact O-N 2.95Å; V79-H81 PolarHBondContact O-ND1 3.35Å; V79-I91 HydrophobicContact CB-CD1 4.46Å; V79-I96 HydrophobicContact CG2-CG2 4.18Å; V79-Y97 HydrophobicContact CB-CE1 4.27Å; V79-Y97 WeakPolarHBondContact O-CE1 3.41Å; V79-Y97 PolarHBondContact O-OH 2.88Å; V79-D100 WeakPolarHBondContact CG2-OD2 3.46Å
80G98.2Very high97.8Very high1 Ų115.6 Ų15.61%0.018%0.084CC..THydrogen-bonded Turntrans78.18.5-179.300000115H78 E85 E87 R88 M89H78-G80 PolarHBondContact O-N 3.35Å; G80-E85 PolarHBondContact N-O 3.23Å; G80-E87 VanDerWaalsContact CA-O 3.24Å; G80-E87 WeakPolarHBondContact CA-O 3.42Å; G80-R88 VanDerWaalsContact CA-NH2 3.27Å; G80-R88 WeakPolarHBondContact O-CA 3.32Å; G80-R88 PolarHBondContact O-NE 2.81Å; G80-M89 PolarHBondContact O-N 3.47Å
81H98.7Very high97.7Very high4 Ų414.8 Ų14.82%0.0198%0.078CC..SBendtrans-126.8157.9-178.2-64.474.6000112.7H50 G53 E54 H78 V79 Q83 S84 R88 M89 Y97H50-H81 AromaticContact CE1-CD2 3.71Å; H50-H81 AromaticContact CE1-CG 3.66Å; G53-H81 PolarHBondContact N-CD2 2.97Å; G53-H81 VanDerWaalsContact N-CD2 3.25Å; G53-H81 PolarHBondContact N-NE2 3.26Å; G53-H81 VanDerWaalsContact N-NE2 3.12Å; E54-H81 PolarHBondContact O-CD2 3.11Å; H78-H81 VanDerWaalsContact O-CB 3.3Å; H78-H81 WeakPolarHBondContact O-CB 3.45Å; H78-H81 PolarHBondContact O-N 3.26Å; V79-H81 VanDerWaalsContact C-N 3.29Å; V79-H81 PolarHBondContact O-N 2.95Å; V79-H81 PolarHBondContact O-ND1 3.35Å; H81-Q83 PolarHBondContact O-N 2.95Å; H81-S84 WeakPolarHBondContact O-CB 3.43Å; H81-S84 PolarHBondContact O-N 3.05Å; H81-R88 PolarHBondContact O-NH1 3.42Å; H81-M89 PolarHBondContact NE2-SD 3.34Å; H81-Y97 PolarHBondContact CE1-OH 3.09Å
82G98.4Very high97.4Very high4 Ų423.1 Ų23.14%0.04111%0.109CC..THydrogen-bonded Turntrans41.3-122174.900000114.1Q13 R88Q13-G82 PolarHBondContact NE2-O 2.82Å; G82-R88 PolarHBondContact O-NH1 2.88Å
83Q98.7Very high97.3Very high26 Ų2626.8 Ų26.812%0.12113%0.129CC..THydrogen-bonded Turntrans-92.1-1.7-178.7-64.4176.790.800114S11 P12 Y17 F32 D77 H81 L200S11-Q83 WeakPolarHBondContact CB-O 3.41Å; P12-Q83 WeakPolarHBondContact CD-O 3.45Å; Y17-Q83 PolarHBondContact OH-O 2.96Å; F32-Q83 HydrophobicContact CB-CB 3.63Å; F32-Q83 HydrophobicContact CD1-CB 4.27Å; F32-Q83 HydrophobicContact CD2-CB 4.01Å; F32-Q83 VanDerWaalsContact CE1-NE2 3.35Å; F32-Q83 HydrophobicContact CG-CB 3.7Å; D77-Q83 PolarHBondContact OD2-N 3.49Å; H81-Q83 PolarHBondContact O-N 2.95Å; Q83-L200 HydrophobicContact CG-CD1 4.06Å; Q83-L200 HydrophobicContact CG-CD2 3.74Å
84S98.8Very high97.2Very high0 Ų027.1 Ų27.10%013%0.13CC..SBendtrans-77.4157.7176.6-71.90000112.6P12 Y17 L31 F32 D77 H81 R88P12-S84 VanDerWaalsContact CG-O 3.29Å; P12-S84 WeakPolarHBondContact CG-O 3.48Å; Y17-S84 VanDerWaalsContact OH-CA 3.3Å; Y17-S84 WeakPolarHBondContact OH-CA 3.46Å; L31-S84 WeakPolarHBondContact CA-OG 3.42Å; F32-S84 PolarHBondContact N-OG 3.36Å; D77-S84 WeakPolarHBondContact CB-OG 3.33Å; D77-S84 WeakPolarHBondContact O-CB 3.26Å; D77-S84 PolarHBondContact O-OG 3.48Å; H81-S84 WeakPolarHBondContact O-CB 3.43Å; H81-S84 PolarHBondContact O-N 3.05Å; S84-R88 PolarHBondContact O-NH1 2.9Å; S84-R88 PolarHBondContact O-NH2 3.28Å
85E98.5Very high97.2Very high23 Ų2329.4 Ų29.411%0.10714%0.141CC..  trans-71.6174.4173.2-69.5-174.9146.200112.4R9 Y17 L29 H30 G80 R88R9-E85 IonicContact CZ-OE1 2.9Å; R9-E85 IonicContact CZ-OE2 3.1Å; R9-E85 IonicContact NE-OE1 2.77Å; R9-E85 PolarHBondContact NE-OE1 2.81Å; R9-E85 IonicContact NE-OE2 3.37Å; R9-E85 VanDerWaalsContact NH2-CD 3.31Å; R9-E85 IonicContact NH2-OE1 2.83Å; R9-E85 PolarHBondContact NH2-OE1 2.97Å; R9-E85 IonicContact NH2-OE2 3.34Å; R9-E85 PolarHBondContact NH2-OE2 3.46Å; Y17-E85 HydrophobicContact CE2-CG 3.62Å; Y17-E85 WeakPolarHBondContact OH-CG 3.3Å; Y17-E85 PolarHBondContact OH-N 2.91Å; L29-E85 WeakPolarHBondContact CA-OE2 3.13Å; L29-E85 HydrophobicContact CB-CB 4.19Å; L29-E85 HydrophobicContact CD2-CB 4.18Å; H30-E85 HydrophobicContact CB-CG 4.08Å; H30-E85 IonicContact CD2-OE2 2.79Å; H30-E85 PolarHBondContact N-OE2 3.02Å; H30-E85 PolarHBondContact O-N 3.49Å; G80-E85 PolarHBondContact N-O 3.23Å; E85-R88 PolarHBondContact O-NH2 2.86Å
86G97.2Very high97.2Very high29 Ų2930 Ų3030%0.29914%0.144SC..SBendtrans106.9159.6-17900000112.6R88G86-R88 PolarHBondContact O-N 2.96Å; G86-R88 PolarHBondContact O-NE 2.99Å; G86-R88 PolarHBondContact O-NH2 2.75Å
87E95.7Very high97.2Very high101 Ų10130 Ų3047%0.47214%0.144SC..SBendtrans-66.6133.9175.5-173.2172.9-153.400110.3G80 M89 N90 R207G80-E87 VanDerWaalsContact CA-O 3.24Å; G80-E87 WeakPolarHBondContact CA-O 3.42Å; E87-M89 PolarHBondContact O-N 2.95Å; E87-N90 HydrophobicContact CB-CB 4.23Å; E87-N90 HydrophobicContact CG-CB 4.14Å; E87-N90 PolarHBondContact O-N 2.96Å; E87-N90 PolarHBondContact OE2-ND2 3.13Å; E87-R207 IonicContact OE1-CZ 3.76Å; E87-R207 IonicContact OE1-NH1 3.38Å; E87-R207 PolarHBondContact OE1-NH1 2.95Å; E87-R207 IonicContact OE1-NH2 3.76Å; E87-R207 PolarHBondContact OE1-NH2 3.28Å; E87-R207 IonicContact OE2-NH1 2.87Å; E87-R207 PolarHBondContact OE2-NH1 3.41Å; E87-R207 VanDerWaalsContact OE2-NH1 3.11Å
88R95.8Very high97.2Very high61 Ų6130 Ų3023%0.2314%0.144CC..THydrogen-bonded Turntrans-58.9127.6-173.7-63.3-58.484176.50.5111.4G80 H81 G82 S84 E85 G86 N90 Y202G80-R88 VanDerWaalsContact CA-NH2 3.27Å; G80-R88 WeakPolarHBondContact O-CA 3.32Å; G80-R88 PolarHBondContact O-NE 2.81Å; H81-R88 PolarHBondContact O-NH1 3.42Å; G82-R88 PolarHBondContact O-NH1 2.88Å; S84-R88 PolarHBondContact O-NH1 2.9Å; S84-R88 PolarHBondContact O-NH2 3.28Å; E85-R88 PolarHBondContact O-NH2 2.86Å; G86-R88 PolarHBondContact O-N 2.96Å; G86-R88 PolarHBondContact O-NE 2.99Å; G86-R88 PolarHBondContact O-NH2 2.75Å; R88-N90 PolarHBondContact O-N 3.1Å; R88-N90 VanDerWaalsContact O-N 3.14Å; R88-Y202 HydrophobicContact CB-CD2 3.76Å; R88-Y202 HydrophobicContact CB-CE2 3.75Å; R88-Y202 HydrophobicContact CG-CD2 4.43Å
89M93.2Very high97.2Very high7 Ų732.9 Ų32.93%0.03416%0.155CC..THydrogen-bonded Turntrans49.440.7176.3-79.2-76.7-78.900113.1A52 G53 G80 H81 E87 Y202 L206 F210A52-M89 HydrophobicContact CB-CE 3.98Å; A52-M89 HydrophobicContact CB-SD 4.17Å; G53-M89 VanDerWaalsContact CA-SD 3.58Å; G53-M89 PolarHBondContact N-SD 3.19Å; G80-M89 PolarHBondContact O-N 3.47Å; H81-M89 PolarHBondContact NE2-SD 3.34Å; E87-M89 PolarHBondContact O-N 2.95Å; M89-Y202 HydrophobicContact CB-CD1 3.82Å; M89-Y202 HydrophobicContact CB-CD2 4.49Å; M89-Y202 HydrophobicContact CB-CE1 3.84Å; M89-Y202 HydrophobicContact CB-CG 4.12Å; M89-Y202 HydrophobicContact CE-CD1 4.43Å; M89-Y202 HydrophobicContact CG-CD1 3.41Å; M89-Y202 VanDerWaalsContact CG-CD1 3.41Å; M89-Y202 HydrophobicContact CG-CD2 4.27Å; M89-Y202 HydrophobicContact CG-CE1 3.98Å; M89-Y202 HydrophobicContact CG-CG 3.54Å; M89-L206 HydrophobicContact CE-CD1 3.8Å; M89-F210 HydrophobicContact CE-CD1 3.93Å; M89-F210 HydrophobicContact CE-CE1 3.52Å; M89-F210 HydrophobicContact CE-CZ 4.4Å; M89-F210 WeakPolarHBondContact O-CB 3.45Å; M89-F210 VanDerWaalsContact O-CG 3.24Å; M89-F210 WeakPolarHBondContact O-CG 3.48Å; M89-F210 HydrophobicContact SD-CD1 4.31Å; M89-F210 HydrophobicContact SD-CE1 3.66Å; M89-F210 HydrophobicContact SD-CZ 3.96Å
90N92.9Very high97.2Very high32 Ų3232.4 Ų32.417%0.17115%0.152CC..  trans-140.7141.1174.9-16628.2000110.3E87 R88 S209E87-N90 HydrophobicContact CB-CB 4.23Å; E87-N90 HydrophobicContact CG-CB 4.14Å; E87-N90 PolarHBondContact O-N 2.96Å; E87-N90 PolarHBondContact OE2-ND2 3.13Å; R88-N90 PolarHBondContact O-N 3.1Å; R88-N90 VanDerWaalsContact O-N 3.14Å; N90-S209 PolarHBondContact OD1-OG 2.85Å
91I95.3Very high97.3Very high10 Ų1032.4 Ų32.45%0.05115%0.152CC..  trans-150.6146.4176.4-158.2153.6000110.6V79 I96 Y97 F210 Q213V79-I91 HydrophobicContact CB-CD1 4.46Å; I91-I96 HydrophobicContact CD1-CB 3.68Å; I91-I96 HydrophobicContact CD1-CD1 4.16Å; I91-I96 HydrophobicContact CD1-CG2 3.74Å; I91-I96 HydrophobicContact CG1-CB 4.26Å; I91-I96 HydrophobicContact CG1-CD1 3.81Å; I91-Y97 HydrophobicContact CB-CE2 4.45Å; I91-Y97 HydrophobicContact CD1-CD1 3.8Å; I91-Y97 HydrophobicContact CD1-CD2 4.06Å; I91-Y97 HydrophobicContact CD1-CE1 3.38Å; I91-Y97 HydrophobicContact CD1-CE2 3.7Å; I91-Y97 HydrophobicContact CD1-CG 4.11Å; I91-Y97 HydrophobicContact CG2-CE2 4Å; I91-F210 HydrophobicContact CG2-CD2 4.01Å; I91-F210 HydrophobicContact CG2-CE2 4.04Å; I91-Q213 HydrophobicContact CG2-CB 4.12Å; I91-Q213 HydrophobicContact CG2-CG 3.92Å
92R93.3Very high97.3Very high174 Ų17432.5 Ų32.566%0.65715%0.152SC*.SBendtrans-73.4-33.917962.3172.4175.4149.61.3113D27 I96 Q213D27-R92 IonicContact OD1-NH2 2.73Å; D27-R92 PolarHBondContact OD1-NH2 2.81Å; D27-R92 IonicContact OD2-NH2 3.25Å; D27-R92 PolarHBondContact OD2-NH2 3.1Å; R92-I96 HydrophobicContact CG-CD1 3.38Å; R92-Q213 PolarHBondContact O-NE2 2.88Å; R92-Q213 VanDerWaalsContact O-NE2 3.11Å
93D96.1Very high97.3Very high80 Ų8035.3 Ų35.343%0.42816%0.164SC..  trans-154.5127.3-175.3-172.8-20.8000108.6Q95 I96D93-Q95 PolarHBondContact O-N 3.34Å; D93-Q95 VanDerWaalsContact O-N 3.17Å; D93-Q95 WeakPolarHBondContact OD1-CB 3.4Å; D93-Q95 PolarHBondContact OD1-N 2.9Å; D93-I96 HydrophobicContact CB-CD1 4.47Å; D93-I96 WeakPolarHBondContact O-CB 3.37Å; D93-I96 PolarHBondContact O-N 2.89Å; D93-I96 VanDerWaalsContact O-N 3.13Å
94F98.3Very high97.3Very high7 Ų734.1 Ų34.13%0.03116%0.159CC..THydrogen-bonded Turntrans-57.7-26.2176.7-160.2-93.6000112.9I96 Y97 I98 M124 A127 I128 L131 Q213 L214 A217F94-I96 PolarHBondContact O-N 3.04Å; F94-I96 VanDerWaalsContact O-N 3.09Å; F94-Y97 AromaticContact CD2-CD2 3.81Å; F94-Y97 HydrophobicContact CD2-CD2 3.81Å; F94-Y97 HydrophobicContact CD2-CE2 4.07Å; F94-Y97 AromaticContact CE2-CD2 3.81Å; F94-Y97 HydrophobicContact CE2-CD2 3.81Å; F94-Y97 HydrophobicContact CE2-CE2 4.1Å; F94-Y97 HydrophobicContact CG-CD2 4.22Å; F94-Y97 HydrophobicContact CZ-CD2 4.23Å; F94-Y97 PolarHBondContact O-N 3.06Å; F94-I98 HydrophobicContact CD1-CD1 3.56Å; F94-I98 HydrophobicContact CE1-CD1 3.81Å; F94-I98 VanDerWaalsContact O-CD1 3.29Å; F94-I98 WeakPolarHBondContact O-CD1 3.14Å; F94-M124 HydrophobicContact CE2-CG 3.81Å; F94-M124 HydrophobicContact CE2-SD 4.15Å; F94-M124 HydrophobicContact CZ-CG 3.9Å; F94-A127 HydrophobicContact CE1-CB 4.48Å; F94-A127 HydrophobicContact CZ-CB 4.18Å; F94-I128 HydrophobicContact CE1-CG1 3.81Å; F94-I128 HydrophobicContact CZ-CD1 4.39Å; F94-I128 HydrophobicContact CZ-CG1 3.64Å; F94-L131 HydrophobicContact CD1-CD1 4.01Å; F94-L131 HydrophobicContact CE1-CD1 3.99Å; F94-Q213 HydrophobicContact CB-CB 4.36Å; F94-Q213 HydrophobicContact CD2-CB 4.45Å; F94-L214 HydrophobicContact CE2-CD2 3.97Å; F94-A217 HydrophobicContact CB-CB 4.39Å; F94-A217 HydrophobicContact CD1-CB 3.51Å; F94-A217 HydrophobicContact CD2-CB 3.91Å; F94-A217 HydrophobicContact CE1-CB 3.61Å; F94-A217 HydrophobicContact CE2-CB 4Å; F94-A217 HydrophobicContact CG-CB 3.67Å; F94-A217 HydrophobicContact CZ-CB 3.85Å
95Q98.6Very high97.3Very high48 Ų4834.1 Ų34.122%0.22416%0.159CC..Hα-helixtrans-57.2-23.9176.3-176.958.119.200113.3D93 Y97 I98 R99 E135D93-Q95 PolarHBondContact O-N 3.34Å; D93-Q95 VanDerWaalsContact O-N 3.17Å; D93-Q95 WeakPolarHBondContact OD1-CB 3.4Å; D93-Q95 PolarHBondContact OD1-N 2.9Å; Q95-Y97 VanDerWaalsContact C-N 3.29Å; Q95-Y97 PolarHBondContact O-N 2.83Å; Q95-I98 PolarHBondContact O-N 2.77Å; Q95-R99 WeakPolarHBondContact O-CB 3.46Å; Q95-R99 PolarHBondContact O-N 3.47Å; Q95-E135 PolarHBondContact NE2-OE2 2.98Å
96I98.8Very high97.3Very high11 Ų1135.7 Ų35.76%0.05617%0.168CC..Hα-helixtrans-60-40.8175.7-71.4160.5000111.3V79 I91 R92 D93 F94 I98 R99 D100V79-I96 HydrophobicContact CG2-CG2 4.18Å; I91-I96 HydrophobicContact CD1-CB 3.68Å; I91-I96 HydrophobicContact CD1-CD1 4.16Å; I91-I96 HydrophobicContact CD1-CG2 3.74Å; I91-I96 HydrophobicContact CG1-CB 4.26Å; I91-I96 HydrophobicContact CG1-CD1 3.81Å; R92-I96 HydrophobicContact CG-CD1 3.38Å; D93-I96 HydrophobicContact CB-CD1 4.47Å; D93-I96 WeakPolarHBondContact O-CB 3.37Å; D93-I96 PolarHBondContact O-N 2.89Å; D93-I96 VanDerWaalsContact O-N 3.13Å; F94-I96 PolarHBondContact O-N 3.04Å; F94-I96 VanDerWaalsContact O-N 3.09Å; I96-I98 VanDerWaalsContact C-N 3.31Å; I96-I98 PolarHBondContact O-N 3.2Å; I96-R99 PolarHBondContact O-N 3.45Å; I96-D100 VanDerWaalsContact O-CB 3.32Å; I96-D100 WeakPolarHBondContact O-CB 3.38Å; I96-D100 PolarHBondContact O-N 3.05Å
97Y98.9Very high97.4Very high1 Ų137.4 Ų37.40%0.00417%0.17CC..Hα-helixtrans-64.3-38.3178.5-63.5-47.4000112.3H78 V79 H81 I91 F94 Q95 S101 M124 I128 F210H78-Y97 HydrophobicContact CB-CD1 3.75Å; H78-Y97 HydrophobicContact CB-CE1 3.64Å; V79-Y97 HydrophobicContact CB-CE1 4.27Å; V79-Y97 WeakPolarHBondContact O-CE1 3.41Å; V79-Y97 PolarHBondContact O-OH 2.88Å; H81-Y97 PolarHBondContact CE1-OH 3.09Å; I91-Y97 HydrophobicContact CB-CE2 4.45Å; I91-Y97 HydrophobicContact CD1-CD1 3.8Å; I91-Y97 HydrophobicContact CD1-CD2 4.06Å; I91-Y97 HydrophobicContact CD1-CE1 3.38Å; I91-Y97 HydrophobicContact CD1-CE2 3.7Å; I91-Y97 HydrophobicContact CD1-CG 4.11Å; I91-Y97 HydrophobicContact CG2-CE2 4Å; F94-Y97 AromaticContact CD2-CD2 3.81Å; F94-Y97 HydrophobicContact CD2-CD2 3.81Å; F94-Y97 HydrophobicContact CD2-CE2 4.07Å; F94-Y97 AromaticContact CE2-CD2 3.81Å; F94-Y97 HydrophobicContact CE2-CD2 3.81Å; F94-Y97 HydrophobicContact CE2-CE2 4.1Å; F94-Y97 HydrophobicContact CG-CD2 4.22Å; F94-Y97 HydrophobicContact CZ-CD2 4.23Å; F94-Y97 PolarHBondContact O-N 3.06Å; Q95-Y97 VanDerWaalsContact C-N 3.29Å; Q95-Y97 PolarHBondContact O-N 2.83Å; Y97-S101 VanDerWaalsContact O-CB 3.3Å; Y97-S101 WeakPolarHBondContact O-CB 3.44Å; Y97-S101 PolarHBondContact O-N 2.8Å; Y97-S101 PolarHBondContact O-OG 3.42Å; Y97-M124 HydrophobicContact CE2-CE 4.44Å; Y97-M124 HydrophobicContact CE2-SD 4.13Å; Y97-I128 HydrophobicContact CD2-CD1 4.05Å; Y97-I128 HydrophobicContact CD2-CG1 4.42Å; Y97-I128 HydrophobicContact CG-CD1 3.86Å; Y97-I128 HydrophobicContact CG-CG1 4.36Å; Y97-F210 HydrophobicContact CE2-CE2 4.11Å; Y97-F210 WeakPolarHBondContact OH-CE2 3.38Å
98I98.9Very high97.5Very high0 Ų033.4 Ų33.40%015%0.151CC..Hα-helixtrans-66.6-49.6176.4-68.782000110F94 Q95 I96 D100 S101 L102 L131 E135F94-I98 HydrophobicContact CD1-CD1 3.56Å; F94-I98 HydrophobicContact CE1-CD1 3.81Å; F94-I98 VanDerWaalsContact O-CD1 3.29Å; F94-I98 WeakPolarHBondContact O-CD1 3.14Å; Q95-I98 PolarHBondContact O-N 2.77Å; I96-I98 VanDerWaalsContact C-N 3.31Å; I96-I98 PolarHBondContact O-N 3.2Å; I98-D100 VanDerWaalsContact C-N 3.34Å; I98-D100 PolarHBondContact O-N 3.13Å; I98-S101 WeakPolarHBondContact O-CB 3.4Å; I98-S101 PolarHBondContact O-N 3.01Å; I98-L102 HydrophobicContact CG2-CD1 4.05Å; I98-L102 HydrophobicContact CG2-CG 4.48Å; I98-L102 WeakPolarHBondContact O-CG 3.41Å; I98-L102 PolarHBondContact O-N 3Å; I98-L131 HydrophobicContact CD1-CB 4Å; I98-L131 HydrophobicContact CD1-CD1 4.05Å; I98-L131 HydrophobicContact CG1-CB 3.65Å; I98-E135 WeakPolarHBondContact CG2-OE2 3.33Å
99R98.8Very high97.6Very high61 Ų6133.3 Ų33.323%0.2315%0.153CC..Hα-helixtrans-56-48.1178.1-179.5-162.767.2-168.7-2.4111.6N25 D27 Q95 I96 S101 L102 Q103N25-R99 PolarHBondContact ND2-NH2 2.88Å; D27-R99 VanDerWaalsContact CG-NH2 3.29Å; D27-R99 IonicContact OD1-CZ 3.23Å; D27-R99 IonicContact OD1-NH1 3.8Å; D27-R99 PolarHBondContact OD1-NH1 2.7Å; D27-R99 IonicContact OD1-NH2 3.11Å; D27-R99 IonicContact OD2-CZ 2.74Å; D27-R99 IonicContact OD2-NH1 3.5Å; D27-R99 PolarHBondContact OD2-NH1 2.9Å; D27-R99 VanDerWaalsContact OD2-NH1 3.1Å; D27-R99 IonicContact OD2-NH2 3.53Å; D27-R99 PolarHBondContact OD2-NH2 3.36Å; Q95-R99 WeakPolarHBondContact O-CB 3.46Å; Q95-R99 PolarHBondContact O-N 3.47Å; I96-R99 PolarHBondContact O-N 3.45Å; R99-S101 VanDerWaalsContact C-N 3.34Å; R99-L102 PolarHBondContact O-N 3.11Å; R99-Q103 WeakPolarHBondContact O-CB 3.35Å; R99-Q103 PolarHBondContact O-N 3.38Å
100D98.9Very high97.8Very high1 Ų137 Ų371%0.00518%0.179CC..Hα-helixtrans-70.4-33.6-176.8-662.3000111N25 L31 H76 V79 I96 I98 Q103 H104N25-D100 PolarHBondContact ND2-OD2 3.06Å; L31-D100 HydrophobicContact CD1-CB 3.88Å; H76-D100 PolarHBondContact CE1-O 2.86Å; V79-D100 WeakPolarHBondContact CG2-OD2 3.46Å; I96-D100 VanDerWaalsContact O-CB 3.32Å; I96-D100 WeakPolarHBondContact O-CB 3.38Å; I96-D100 PolarHBondContact O-N 3.05Å; I98-D100 VanDerWaalsContact C-N 3.34Å; I98-D100 PolarHBondContact O-N 3.13Å; D100-Q103 PolarHBondContact O-N 2.94Å; D100-H104 PolarHBondContact O-N 3.36Å
101S98.9Very high97.9Very high0 Ų041.4 Ų41.40%020%0.198CC..Hα-helixtrans-62.9-49.7171.2-60.50000111.3F47 Y97 I98 R99 Q103 H104 I105 I128F47-S101 WeakPolarHBondContact CE1-OG 3.49Å; Y97-S101 VanDerWaalsContact O-CB 3.3Å; Y97-S101 WeakPolarHBondContact O-CB 3.44Å; Y97-S101 PolarHBondContact O-N 2.8Å; Y97-S101 PolarHBondContact O-OG 3.42Å; I98-S101 WeakPolarHBondContact O-CB 3.4Å; I98-S101 PolarHBondContact O-N 3.01Å; R99-S101 VanDerWaalsContact C-N 3.34Å; S101-Q103 VanDerWaalsContact C-N 3.32Å; S101-Q103 PolarHBondContact O-N 3.01Å; S101-H104 PolarHBondContact O-N 2.98Å; S101-I105 WeakPolarHBondContact O-CB 3.44Å; S101-I105 WeakPolarHBondContact O-CD1 3.23Å; S101-I105 VanDerWaalsContact O-CG1 3.23Å; S101-I105 WeakPolarHBondContact O-CG1 3.3Å; S101-I105 PolarHBondContact O-N 2.91Å; S101-I128 WeakPolarHBondContact OG-CG2 3.42Å
102L98.9Very high97.9Very high6 Ų644.7 Ų44.73%0.03121%0.21CC..Hα-helixtrans-60.2-40.4175.6-72.3174000112I98 R99 H104 I105 D106 T132 E135 R136 F140I98-L102 HydrophobicContact CG2-CD1 4.05Å; I98-L102 HydrophobicContact CG2-CG 4.48Å; I98-L102 WeakPolarHBondContact O-CG 3.41Å; I98-L102 PolarHBondContact O-N 3Å; R99-L102 PolarHBondContact O-N 3.11Å; L102-H104 PolarHBondContact O-N 2.92Å; L102-I105 PolarHBondContact O-N 2.83Å; L102-D106 VanDerWaalsContact O-CB 3.3Å; L102-D106 WeakPolarHBondContact O-CB 3.24Å; L102-D106 PolarHBondContact O-N 3Å; L102-T132 HydrophobicContact CD2-CG2 3.67Å; L102-T132 HydrophobicContact CG-CG2 4.01Å; L102-E135 HydrophobicContact CD1-CB 4.4Å; L102-E135 HydrophobicContact CD1-CG 4.14Å; L102-R136 HydrophobicContact CD2-CG 4.18Å; L102-F140 HydrophobicContact CD2-CZ 4.24Å
103Q98.9Very high97.8Very high64 Ų6440.5 Ų40.530%0.29921%0.205SC..Hα-helixtrans-59.3-46.2175-178.8-176.2-2.500111.7V24 N25 R99 D100 S101 D106 L107V24-Q103 PolarHBondContact O-NE2 3.31Å; N25-Q103 VanDerWaalsContact CA-OE1 3.29Å; R99-Q103 WeakPolarHBondContact O-CB 3.35Å; R99-Q103 PolarHBondContact O-N 3.38Å; D100-Q103 PolarHBondContact O-N 2.94Å; S101-Q103 VanDerWaalsContact C-N 3.32Å; S101-Q103 PolarHBondContact O-N 3.01Å; Q103-D106 PolarHBondContact O-N 3.18Å; Q103-L107 WeakPolarHBondContact O-CB 3.37Å; Q103-L107 PolarHBondContact O-N 2.87Å
104H98.9Very high97.7Very high0 Ų044.6 Ų44.60%023%0.227CC..Hα-helixtrans-67.6-41.3179.5-161.6179000111.4I23 Y35 F47 F74 A75 H76 D100 S101 L102 L107 M108I23-H104 HydrophobicContact CD1-CB 3.85Å; Y35-H104 AromaticContact CE1-NE2 3.62Å; Y35-H104 AromaticContact CZ-NE2 3.57Å; Y35-H104 PolarHBondContact OH-NE2 2.86Å; F47-H104 AromaticContact CE2-ND1 3.94Å; F74-H104 AromaticContact CD2-CD2 3.83Å; F74-H104 AromaticContact CD2-CE1 3.74Å; F74-H104 AromaticContact CD2-CG 3.96Å; F74-H104 AromaticContact CD2-ND1 3.89Å; F74-H104 AromaticContact CD2-NE2 3.68Å; F74-H104 HydrophobicContact CE2-CB 4.48Å; A75-H104 PolarHBondContact O-CE1 3.35Å; H76-H104 AromaticContact CG-ND1 3.78Å; H76-H104 AromaticContact ND1-CG 3.75Å; H76-H104 AromaticContact ND1-ND1 3.15Å; H76-H104 PolarHBondContact ND1-ND1 3.34Å; H76-H104 VanDerWaalsContact ND1-ND1 3.15Å; D100-H104 PolarHBondContact O-N 3.36Å; S101-H104 PolarHBondContact O-N 2.98Å; L102-H104 PolarHBondContact O-N 2.92Å; H104-L107 WeakPolarHBondContact O-CB 3.42Å; H104-L107 PolarHBondContact O-N 3.09Å; H104-M108 WeakPolarHBondContact O-CG 3.32Å; H104-M108 PolarHBondContact O-N 3.49Å
105I98.8Very high97.6Very high0 Ų046.4 Ų46.40%024%0.237CC..Hα-helixtrans-62.2-45.2176.2-69.4159.6000110.8F47 F74 S101 L102 L107 M108 K109 V117 T132 F140F47-I105 HydrophobicContact CB-CD1 4.26Å; F47-I105 HydrophobicContact CB-CG1 4.05Å; F47-I105 HydrophobicContact CD1-CD1 4.04Å; F47-I105 HydrophobicContact CD1-CG1 4.43Å; F47-I105 HydrophobicContact CG-CD1 4.18Å; F47-I105 HydrophobicContact CG-CG1 4.09Å; F74-I105 HydrophobicContact CE2-CG1 4.15Å; F74-I105 HydrophobicContact CZ-CG1 3.93Å; S101-I105 WeakPolarHBondContact O-CB 3.44Å; S101-I105 WeakPolarHBondContact O-CD1 3.23Å; S101-I105 VanDerWaalsContact O-CG1 3.23Å; S101-I105 WeakPolarHBondContact O-CG1 3.3Å; S101-I105 PolarHBondContact O-N 2.91Å; L102-I105 PolarHBondContact O-N 2.83Å; I105-L107 VanDerWaalsContact C-N 3.34Å; I105-L107 PolarHBondContact O-N 2.96Å; I105-M108 PolarHBondContact O-N 3.33Å; I105-K109 HydrophobicContact CG2-CD 3.84Å; I105-K109 HydrophobicContact CG2-CG 4.34Å; I105-K109 WeakPolarHBondContact O-CG 3.48Å; I105-K109 PolarHBondContact O-N 2.86Å; I105-V117 HydrophobicContact CG2-CG1 4.11Å; I105-T132 HydrophobicContact CD1-CG2 4.11Å; I105-F140 HydrophobicContact CD1-CE1 3.98Å; I105-F140 HydrophobicContact CD1-CZ 4.21Å; I105-F140 HydrophobicContact CG2-CE1 4.29Å
106D98.6Very high97.6Very high56 Ų5645 Ų4530%0.29923%0.232SC..Hα-helixtrans-63.1-40.5177.8-75-21.9000111.7L102 Q103 M108 K109 S110 R136L102-D106 VanDerWaalsContact O-CB 3.3Å; L102-D106 WeakPolarHBondContact O-CB 3.24Å; L102-D106 PolarHBondContact O-N 3Å; Q103-D106 PolarHBondContact O-N 3.18Å; D106-M108 VanDerWaalsContact C-N 3.33Å; D106-M108 PolarHBondContact O-N 3.33Å; D106-K109 PolarHBondContact O-N 2.79Å; D106-S110 WeakPolarHBondContact O-CB 3.46Å; D106-S110 PolarHBondContact O-N 3.18Å; D106-R136 IonicContact OD1-CZ 3.78Å; D106-R136 IonicContact OD1-NH1 2.71Å; D106-R136 PolarHBondContact OD1-NH1 2.85Å; D106-R136 IonicContact OD1-NH2 3.99Å; D106-R136 IonicContact OD2-CZ 3.35Å; D106-R136 IonicContact OD2-NH1 2.99Å; D106-R136 PolarHBondContact OD2-NH1 2.8Å; D106-R136 IonicContact OD2-NH2 2.8Å; D106-R136 PolarHBondContact OD2-NH2 3.01Å
107L98.6Very high97.6Very high65 Ų6544.7 Ų44.734%0.3423%0.23SC..Hα-helixtrans-58-46.8173.1-176.966.5000110.7I23 Q103 H104 I105 S110 H111I23-L107 HydrophobicContact CG2-CD2 3.64Å; Q103-L107 WeakPolarHBondContact O-CB 3.37Å; Q103-L107 PolarHBondContact O-N 2.87Å; H104-L107 WeakPolarHBondContact O-CB 3.42Å; H104-L107 PolarHBondContact O-N 3.09Å; I105-L107 VanDerWaalsContact C-N 3.34Å; I105-L107 PolarHBondContact O-N 2.96Å; L107-S110 PolarHBondContact O-N 2.93Å; L107-S110 PolarHBondContact O-OG 3.41Å; L107-H111 PolarHBondContact O-N 3.32Å; L107-H111 PolarHBondContact O-ND1 3.28Å
108M98.3Very high97.6Very high17 Ų1744.6 Ų44.68%0.08423%0.23CC..Hα-helixtrans-69.1-39.7180-66.2-53.4-68.300112.9Y35 L45 L72 F74 H104 I105 D106 S110 H111 R112Y35-M108 HydrophobicContact CD1-CE 4.2Å; Y35-M108 HydrophobicContact CD1-SD 4.34Å; Y35-M108 HydrophobicContact CE1-CE 4.1Å; Y35-M108 HydrophobicContact CE1-SD 3.64Å; L45-M108 HydrophobicContact CD1-CB 3.97Å; L72-M108 HydrophobicContact CD1-CE 3.86Å; L72-M108 HydrophobicContact CD2-CE 3.41Å; L72-M108 VanDerWaalsContact CD2-CE 3.41Å; L72-M108 HydrophobicContact CG-CE 4.32Å; F74-M108 HydrophobicContact CD1-CG 4.16Å; F74-M108 HydrophobicContact CD2-CG 3.56Å; F74-M108 HydrophobicContact CE1-CB 4.27Å; F74-M108 HydrophobicContact CE1-CG 4.18Å; F74-M108 HydrophobicContact CE2-CB 4.13Å; F74-M108 HydrophobicContact CE2-CG 3.55Å; F74-M108 HydrophobicContact CG-CG 3.87Å; F74-M108 HydrophobicContact CZ-CB 3.98Å; F74-M108 HydrophobicContact CZ-CG 3.87Å; H104-M108 WeakPolarHBondContact O-CG 3.32Å; H104-M108 PolarHBondContact O-N 3.49Å; I105-M108 PolarHBondContact O-N 3.33Å; D106-M108 VanDerWaalsContact C-N 3.33Å; D106-M108 PolarHBondContact O-N 3.33Å; M108-S110 VanDerWaalsContact C-N 3.28Å; M108-S110 PolarHBondContact O-N 3.15Å; M108-H111 PolarHBondContact O-N 3.08Å; M108-R112 PolarHBondContact O-N 3.44Å
109K97.7Very high97.6Very high60 Ų6044.7 Ų44.726%0.26123%0.23SC..Hα-helixtrans-60.2-37.5173.4-73.7172.870.7169.50111.7L45 I105 D106 H111 R112 P113 V117 D139L45-K109 HydrophobicContact CD1-CG 4.27Å; I105-K109 HydrophobicContact CG2-CD 3.84Å; I105-K109 HydrophobicContact CG2-CG 4.34Å; I105-K109 WeakPolarHBondContact O-CG 3.48Å; I105-K109 PolarHBondContact O-N 2.86Å; D106-K109 PolarHBondContact O-N 2.79Å; K109-H111 VanDerWaalsContact C-N 3.32Å; K109-H111 PolarHBondContact O-N 3.01Å; K109-R112 CarbonylContact O-C 3.57Å; K109-R112 PolarHBondContact O-N 3.46Å; K109-P113 WeakPolarHBondContact O-CA 3.24Å; K109-P113 VanDerWaalsContact O-N 3.16Å; K109-V117 HydrophobicContact CD-CG2 4.12Å; K109-V117 HydrophobicContact CG-CG2 3.99Å; K109-D139 IonicContact NZ-OD1 3.65Å; K109-D139 PolarHBondContact NZ-OD1 2.78Å; K109-D139 IonicContact NZ-OD2 3.67Å; K109-D139 PolarHBondContact NZ-OD2 3.05Å
110S97.6Very high97.6Very high83 Ų8341.8 Ų41.858%0.5822%0.219SC*.Hα-helixtrans-65.2-34.3178.476.70000113D106 L107 M108D106-S110 WeakPolarHBondContact O-CB 3.46Å; D106-S110 PolarHBondContact O-N 3.18Å; L107-S110 PolarHBondContact O-N 2.93Å; L107-S110 PolarHBondContact O-OG 3.41Å; M108-S110 VanDerWaalsContact C-N 3.28Å; M108-S110 PolarHBondContact O-N 3.15Å
111H96.1Very high97.6Very high126 Ų12641.7 Ų41.758%0.58322%0.219SC*.Hα-helixtrans-83.2-24.2176.6-67.689.7000113L107 M108 K109L107-H111 PolarHBondContact O-N 3.32Å; L107-H111 PolarHBondContact O-ND1 3.28Å; M108-H111 PolarHBondContact O-N 3.08Å; K109-H111 VanDerWaalsContact C-N 3.32Å; K109-H111 PolarHBondContact O-N 3.01Å
112R93.5Very high97.6Very high79 Ų7942 Ų4230%0.29822%0.22SC..SBendtrans-133.269.2-176.3-53.8-66-179.5116.710.2110.4E37 L45 L72 M108 K109 L115E37-R112 IonicContact OE2-NH2 2.97Å; L45-R112 HydrophobicContact CD1-CB 4.36Å; L45-R112 HydrophobicContact CD2-CB 4.1Å; L45-R112 HydrophobicContact CD2-CG 4.14Å; L72-R112 HydrophobicContact CD1-CG 4.5Å; M108-R112 PolarHBondContact O-N 3.44Å; K109-R112 CarbonylContact O-C 3.57Å; K109-R112 PolarHBondContact O-N 3.46Å; R112-L115 HydrophobicContact CB-CD1 3.73Å; R112-L115 HydrophobicContact CB-CG 4.27Å; R112-L115 HydrophobicContact CG-CD1 4.43Å
113P92.8Very high97.5Very high85 Ų8542.4 Ų42.455%0.55222%0.224SC*.THydrogen-bonded Turntrans-63.9151.2-174.726.9-35.2000111.7K109 L115K109-P113 WeakPolarHBondContact O-CA 3.24Å; K109-P113 VanDerWaalsContact O-N 3.16Å; P113-L115 PolarHBondContact O-N 2.81Å; P113-L115 VanDerWaalsContact O-N 3.15Å
114N92.6Very high97.5Very high166 Ų16639.4 Ų39.489%0.88821%0.21SC*.THydrogen-bonded Turntrans64.95.7175.9-49.3-43.2000116.5
115L97Very high97.5Very high46 Ų4639.4 Ų39.424%0.24121%0.21CC..  trans-75.3140.1172-67.1-171.4000111.1P42 L45 R112 P113P42-L115 HydrophobicContact CB-CD1 4.2Å; P42-L115 HydrophobicContact CG-CD1 3.86Å; P42-L115 WeakPolarHBondContact O-CD2 3.41Å; L45-L115 HydrophobicContact CD2-CD1 4.05Å; L45-L115 HydrophobicContact CG-CB 4.17Å; L45-L115 HydrophobicContact CG-CD1 4.22Å; R112-L115 HydrophobicContact CB-CD1 3.73Å; R112-L115 HydrophobicContact CB-CG 4.27Å; R112-L115 HydrophobicContact CG-CD1 4.43Å; P113-L115 PolarHBondContact O-N 2.81Å; P113-L115 VanDerWaalsContact O-N 3.15Å
116P98.1Very high97.5Very high19 Ų1939.4 Ų39.412%0.12321%0.21CC..  trans-50.5142.2163.8-22.730.8000110.9R43 A44 L45 F118 T141 P296R43-P116 WeakPolarHBondContact O-CD 3.43Å; A44-P116 WeakPolarHBondContact CA-O 3.06Å; A44-P116 HydrophobicContact CB-CB 3.97Å; A44-P116 HydrophobicContact CB-CG 4.4Å; A44-P116 WeakPolarHBondContact CB-O 3.33Å; L45-P116 PolarHBondContact N-O 3.07Å; P116-F118 HydrophobicContact CB-CE2 3.95Å; P116-T141 WeakPolarHBondContact CA-OG1 3.44Å; P116-T141 HydrophobicContact CB-CG2 4.26Å; P116-T141 WeakPolarHBondContact CB-OG1 3.45Å; P116-P296 HydrophobicContact CG-CG 3.59Å
117V98.7Very high97.5Very high3 Ų336.7 Ų36.72%0.01820%0.196CC..EExtended strand (participates in β ladder)trans-120.7126.9177.8-173.10000109.2L45 I105 K109 F140 T141L45-V117 HydrophobicContact CB-CG2 4.35Å; L45-V117 HydrophobicContact CD1-CG2 4.29Å; L45-V117 WeakPolarHBondContact O-CA 3.13Å; I105-V117 HydrophobicContact CG2-CG1 4.11Å; K109-V117 HydrophobicContact CD-CG2 4.12Å; K109-V117 HydrophobicContact CG-CG2 3.99Å; V117-F140 HydrophobicContact CB-CD1 4.27Å; V117-F140 HydrophobicContact CG1-CD1 3.93Å; V117-F140 HydrophobicContact CG1-CE1 4.02Å; V117-F140 CarbonylContact O-C 3.57Å; V117-F140 WeakPolarHBondContact O-CA 3.23Å; V117-T141 PolarHBondContact O-N 3.36Å
118F98.9Very high97.5Very high0 Ų033.6 Ų33.60%018%0.179CC..EExtended strand (participates in β ladder)trans-114.3156.5172.7-62.9-94.3000110.4A44 L45 V46 F47 P116 T141 G142 W290 I291 R294 L295A44-F118 HydrophobicContact CB-CD2 4.01Å; A44-F118 HydrophobicContact CB-CE2 3.89Å; L45-F118 PolarHBondContact O-N 2.9Å; V46-F118 WeakPolarHBondContact CA-O 3.49Å; V46-F118 HydrophobicContact CG1-CB 4.32Å; V46-F118 HydrophobicContact CG2-CB 4.27Å; F47-F118 PolarHBondContact N-O 3.37Å; P116-F118 HydrophobicContact CB-CE2 3.95Å; F118-T141 HydrophobicContact CE1-CG2 3.82Å; F118-T141 HydrophobicContact CE2-CG2 4.1Å; F118-T141 HydrophobicContact CZ-CG2 3.43Å; F118-T141 VanDerWaalsContact CZ-CG2 3.43Å; F118-G142 VanDerWaalsContact CA-O 3.26Å; F118-G142 WeakPolarHBondContact CA-O 3.44Å; F118-W290 HydrophobicContact CD1-CZ3 4.19Å; F118-W290 HydrophobicContact CE1-CZ3 4.23Å; F118-I291 HydrophobicContact CD1-CG1 4.19Å; F118-I291 HydrophobicContact CD1-CG2 4.17Å; F118-I291 HydrophobicContact CD2-CG2 3.95Å; F118-I291 HydrophobicContact CE1-CG2 4.23Å; F118-I291 HydrophobicContact CE2-CG2 4.02Å; F118-I291 HydrophobicContact CG-CG1 4.48Å; F118-I291 HydrophobicContact CG-CG2 4.03Å; F118-I291 HydrophobicContact CZ-CG2 4.15Å; F118-R294 HydrophobicContact CE1-CB 3.92Å; F118-R294 HydrophobicContact CZ-CB 3.82Å; F118-L295 HydrophobicContact CE2-CD2 4.07Å
119I98.9Very high97.6Very high1 Ų132.9 Ų32.91%0.00518%0.176CC..EExtended strand (participates in β ladder)trans-122.1136.2168.6-47.1176.5000108.8F47 S129 T132 F140 G142 V143 V144F47-I119 HydrophobicContact CD1-CG2 3.98Å; F47-I119 CarbonylContact O-C 3.5Å; F47-I119 WeakPolarHBondContact O-CA 3.34Å; I119-S129 WeakPolarHBondContact CG2-OG 3.45Å; I119-T132 HydrophobicContact CD1-CG2 3.85Å; I119-F140 HydrophobicContact CD1-CD1 3.76Å; I119-F140 HydrophobicContact CD1-CD2 4.45Å; I119-F140 HydrophobicContact CD1-CE1 3.59Å; I119-F140 HydrophobicContact CD1-CE2 4.29Å; I119-F140 HydrophobicContact CD1-CG 4.2Å; I119-F140 HydrophobicContact CD1-CZ 3.87Å; I119-F140 HydrophobicContact CG1-CD1 3.74Å; I119-F140 HydrophobicContact CG1-CE1 3.84Å; I119-F140 HydrophobicContact CG1-CG 4.44Å; I119-G142 PolarHBondContact N-O 2.99Å; I119-G142 VanDerWaalsContact N-O 3.16Å; I119-V143 HydrophobicContact CB-CG1 4.42Å; I119-V143 CarbonylContact O-C 3.59Å; I119-V143 WeakPolarHBondContact O-CA 3.43Å; I119-V144 PolarHBondContact O-N 3.44Å
120V98.9Very high97.6Very high0 Ų030 Ų300%016%0.163CC..EExtended strand (participates in β ladder)trans-114.2122.1166.6-176.80000107.5V46 F47 I48 A49 V144 I146 V287 I291V46-V120 HydrophobicContact CG1-CG2 3.7Å; F47-V120 PolarHBondContact O-N 3.36Å; I48-V120 CarbonylContact C-O 3.3Å; I48-V120 WeakPolarHBondContact CA-O 3.4Å; I48-V120 HydrophobicContact CG1-CB 4.31Å; A49-V120 PolarHBondContact N-O 2.91Å; V120-V144 CarbonylContact C-O 3.19Å; V120-V144 WeakPolarHBondContact CA-O 3.35Å; V120-V144 HydrophobicContact CG1-CB 4.46Å; V120-V144 HydrophobicContact CG2-CB 4.19Å; V120-I146 HydrophobicContact CG1-CD1 4.27Å; V120-V287 HydrophobicContact CG2-CG1 4.4Å; V120-I291 HydrophobicContact CG2-CD1 3.94Å
121G98.8Very high97.7Very high0 Ų026 Ų260%014%0.136CC..EExtended strand (participates in β ladder)trans-131.1139.6178.800000112.8A49 S129 V144 L145 I146A49-G121 WeakPolarHBondContact O-CA 3.32Å; G121-S129 WeakPolarHBondContact CA-OG 3.5Å; G121-V144 PolarHBondContact N-O 2.97Å; G121-L145 WeakPolarHBondContact O-CA 3.44Å; G121-I146 PolarHBondContact O-N 2.88Å
122H98.7Very high97.8Very high5 Ų520.1 Ų20.12%0.02311%0.108CC..EExtended strand (participates in β ladder)trans-117.7140.8173.416462.9000111.2A49 E54 Y59 M124 G125 G126 I146 H270 H273A49-H122 PolarHBondContact O-N 2.89Å; E54-H122 IonicContact OE1-CD2 3.42Å; Y59-H122 HydrophobicContact CE1-CB 4.23Å; Y59-H122 VanDerWaalsContact OH-CB 3.28Å; Y59-H122 WeakPolarHBondContact OH-CB 3.13Å; Y59-H122 PolarHBondContact OH-CD2 3.43Å; H122-M124 PolarHBondContact O-N 2.8Å; H122-G125 CarbonylContact O-C 3.55Å; H122-G125 WeakPolarHBondContact O-CA 3.25Å; H122-G125 PolarHBondContact O-N 3.22Å; H122-G126 PolarHBondContact O-N 2.88Å; H122-G126 VanDerWaalsContact O-N 3.09Å; H122-I146 WeakPolarHBondContact CA-O 3.28Å; H122-I146 HydrophobicContact CB-CB 4.27Å; H122-I146 PolarHBondContact ND1-O 2.58Å; H122-H270 AromaticContact CE1-CD2 3.65Å; H122-H270 AromaticContact CE1-CE1 3.92Å; H122-H270 AromaticContact CE1-NE2 3.57Å; H122-H270 PolarHBondContact CE1-O 2.86Å; H122-H270 AromaticContact NE2-CD2 3.8Å; H122-H270 AromaticContact NE2-NE2 3.74Å; H122-H273 AromaticContact CD2-CE1 3.67Å; H122-H273 AromaticContact CG-CE1 3.55Å; H122-H273 AromaticContact ND1-CE1 3.82Å
123S97.6Very high98.1Very high16 Ų1616.3 Ų16.311%0.1129%0.094CC..THydrogen-bonded Turntrans54.1-123.3174.5-167.40000112.6G125 G126 A127 I146 G147 M149 H270S123-G125 VanDerWaalsContact C-N 3.28Å; S123-G125 PolarHBondContact O-N 3.08Å; S123-G126 WeakPolarHBondContact O-CA 3.44Å; S123-G126 PolarHBondContact O-N 3.47Å; S123-A127 PolarHBondContact O-N 3.46Å; S123-I146 PolarHBondContact N-O 3.14Å; S123-G147 VanDerWaalsContact CA-O 3.24Å; S123-G147 WeakPolarHBondContact CA-O 3.32Å; S123-G147 PolarHBondContact N-O 3.47Å; S123-M149 WeakPolarHBondContact O-CB 3.15Å; S123-M149 PolarHBondContact O-N 3.15Å; S123-H270 WeakPolarHBondContact CB-NE2 3.33Å; S123-H270 PolarHBondContact OG-CE1 2.95Å; S123-H270 VanDerWaalsContact OG-CE1 3.31Å; S123-H270 PolarHBondContact OG-NE2 3.33Å
124M98.5Very high98.3Very high0 Ų013.2 Ų13.20%07%0.074CC..Hα-helixtrans-55.5-40.2170.4-177.2-170.173.600112.5A52 F94 Y97 H122 G126 A127 I128 F210 L214A52-M124 HydrophobicContact CB-CB 3.92Å; A52-M124 HydrophobicContact CB-CE 4.18Å; A52-M124 HydrophobicContact CB-CG 4.4Å; A52-M124 HydrophobicContact CB-SD 3.71Å; F94-M124 HydrophobicContact CE2-CG 3.81Å; F94-M124 HydrophobicContact CE2-SD 4.15Å; F94-M124 HydrophobicContact CZ-CG 3.9Å; Y97-M124 HydrophobicContact CE2-CE 4.44Å; Y97-M124 HydrophobicContact CE2-SD 4.13Å; H122-M124 PolarHBondContact O-N 2.8Å; M124-G126 PolarHBondContact O-N 2.83Å; M124-A127 WeakPolarHBondContact O-CA 3.34Å; M124-A127 WeakPolarHBondContact O-CB 3.38Å; M124-A127 PolarHBondContact O-N 3.34Å; M124-I128 HydrophobicContact CE-CD1 3.98Å; M124-I128 HydrophobicContact CG-CD1 4.24Å; M124-I128 WeakPolarHBondContact O-CG1 3.36Å; M124-I128 PolarHBondContact O-N 3.05Å; M124-F210 HydrophobicContact SD-CE1 4.44Å; M124-F210 HydrophobicContact SD-CE2 4.49Å; M124-F210 HydrophobicContact SD-CZ 3.63Å; M124-L214 HydrophobicContact CG-CD2 3.95Å; M124-L214 HydrophobicContact SD-CD2 3.92Å
125G98.8Very high98.6Very high0 Ų09.3 Ų9.30%05%0.05CC..Hα-helixtrans-59.3-33.6172.200000112.1A49 H50 H122 S123 I128 S129A49-G125 WeakPolarHBondContact O-CA 3.48Å; H50-G125 WeakPolarHBondContact O-CA 3.5Å; H50-G125 PolarHBondContact O-N 3.28Å; H50-G125 VanDerWaalsContact O-N 3.13Å; H122-G125 CarbonylContact O-C 3.55Å; H122-G125 WeakPolarHBondContact O-CA 3.25Å; H122-G125 PolarHBondContact O-N 3.22Å; S123-G125 VanDerWaalsContact C-N 3.28Å; S123-G125 PolarHBondContact O-N 3.08Å; G125-I128 PolarHBondContact O-N 2.86Å; G125-S129 WeakPolarHBondContact O-CB 3.48Å; G125-S129 PolarHBondContact O-N 3.02Å; G125-S129 PolarHBondContact O-OG 2.82Å
126G98.8Very high98.7Very high0 Ų010.7 Ų10.70%05%0.052CC..Hα-helixtrans-62.5-42.3169.600000112.8H122 S123 M124 S129 I130 L145H122-G126 PolarHBondContact O-N 2.88Å; H122-G126 VanDerWaalsContact O-N 3.09Å; S123-G126 WeakPolarHBondContact O-CA 3.44Å; S123-G126 PolarHBondContact O-N 3.47Å; M124-G126 PolarHBondContact O-N 2.83Å; G126-S129 PolarHBondContact O-N 2.81Å; G126-I130 WeakPolarHBondContact O-CD1 3.33Å; G126-I130 VanDerWaalsContact O-CG1 3.25Å; G126-I130 WeakPolarHBondContact O-CG1 3.45Å; G126-I130 PolarHBondContact O-N 3.44Å; G126-L145 WeakPolarHBondContact O-CD2 3.41Å
127A98.8Very high98.5Very high0 Ų012.6 Ų12.60%07%0.065CC..Hα-helixtrans-63.9-41.2173.600000112.3F94 S123 M124 I130 L131 M149 I221F94-A127 HydrophobicContact CE1-CB 4.48Å; F94-A127 HydrophobicContact CZ-CB 4.18Å; S123-A127 PolarHBondContact O-N 3.46Å; M124-A127 WeakPolarHBondContact O-CA 3.34Å; M124-A127 WeakPolarHBondContact O-CB 3.38Å; M124-A127 PolarHBondContact O-N 3.34Å; A127-I130 PolarHBondContact O-N 2.79Å; A127-L131 WeakPolarHBondContact O-CG 3.36Å; A127-L131 PolarHBondContact O-N 3.47Å; A127-M149 HydrophobicContact CB-CB 4.21Å; A127-M149 HydrophobicContact CB-CE 3.83Å; A127-I221 HydrophobicContact CB-CD1 3.51Å
128I98.9Very high98.3Very high0 Ų018 Ų180%010%0.103CC..Hα-helixtrans-60.4-46.7174.2-65.2164.6000110H78 F94 Y97 S101 M124 G125 I130 L131 T132H78-I128 WeakPolarHBondContact NE2-CD1 3.41Å; F94-I128 HydrophobicContact CE1-CG1 3.81Å; F94-I128 HydrophobicContact CZ-CD1 4.39Å; F94-I128 HydrophobicContact CZ-CG1 3.64Å; Y97-I128 HydrophobicContact CD2-CD1 4.05Å; Y97-I128 HydrophobicContact CD2-CG1 4.42Å; Y97-I128 HydrophobicContact CG-CD1 3.86Å; Y97-I128 HydrophobicContact CG-CG1 4.36Å; S101-I128 WeakPolarHBondContact OG-CG2 3.42Å; M124-I128 HydrophobicContact CE-CD1 3.98Å; M124-I128 HydrophobicContact CG-CD1 4.24Å; M124-I128 WeakPolarHBondContact O-CG1 3.36Å; M124-I128 PolarHBondContact O-N 3.05Å; G125-I128 PolarHBondContact O-N 2.86Å; I128-I130 PolarHBondContact O-N 3.48Å; I128-L131 PolarHBondContact O-N 2.81Å; I128-T132 WeakPolarHBondContact O-CB 3.35Å; I128-T132 PolarHBondContact O-N 2.68Å; I128-T132 PolarHBondContact O-OG1 2.65Å
129S98.9Very high98.2Very high1 Ų120.4 Ų20.41%0.00712%0.116CC..Hα-helixtrans-60-45.5178-60.70000112.6I119 G121 G125 G126 T132 A133I119-S129 WeakPolarHBondContact CG2-OG 3.45Å; G121-S129 WeakPolarHBondContact CA-OG 3.5Å; G125-S129 WeakPolarHBondContact O-CB 3.48Å; G125-S129 PolarHBondContact O-N 3.02Å; G125-S129 PolarHBondContact O-OG 2.82Å; G126-S129 PolarHBondContact O-N 2.81Å; S129-T132 PolarHBondContact O-N 2.86Å; S129-A133 WeakPolarHBondContact O-CB 3.12Å; S129-A133 PolarHBondContact O-N 3.11Å
130I98.9Very high98.1Very high0 Ų020.9 Ų20.90%012%0.118CC..Hα-helixtrans-60-52.5177.5-68.1161.3000110.3G126 A127 I128 T132 A133 C134 L145 P148 V150 I221 I228 W230 M251G126-I130 WeakPolarHBondContact O-CD1 3.33Å; G126-I130 VanDerWaalsContact O-CG1 3.25Å; G126-I130 WeakPolarHBondContact O-CG1 3.45Å; G126-I130 PolarHBondContact O-N 3.44Å; A127-I130 PolarHBondContact O-N 2.79Å; I128-I130 PolarHBondContact O-N 3.48Å; I130-T132 PolarHBondContact O-N 3.4Å; I130-A133 PolarHBondContact O-N 2.87Å; I130-C134 PolarHBondContact O-N 3.38Å; I130-C134 PolarHBondContact O-SG 3.42Å; I130-L145 HydrophobicContact CD1-CD1 3.99Å; I130-L145 HydrophobicContact CD1-CD2 4.42Å; I130-L145 HydrophobicContact CG1-CD1 3.74Å; I130-L145 HydrophobicContact CG1-CD2 3.97Å; I130-P148 HydrophobicContact CD1-CB 4.31Å; I130-V150 HydrophobicContact CD1-CG2 3.75Å; I130-I221 HydrophobicContact CB-CD1 4.48Å; I130-I221 HydrophobicContact CB-CG1 4.46Å; I130-I221 HydrophobicContact CD1-CD1 4.29Å; I130-I221 HydrophobicContact CD1-CG2 4.36Å; I130-I221 HydrophobicContact CG2-CG1 4.02Å; I130-I221 HydrophobicContact CG2-CG2 4.03Å; I130-I228 HydrophobicContact CG2-CD1 3.94Å; I130-W230 HydrophobicContact CB-CH2 4.49Å; I130-W230 HydrophobicContact CG1-CH2 4.2Å; I130-W230 HydrophobicContact CG2-CH2 4.44Å; I130-W230 HydrophobicContact CG2-CZ2 4.24Å; I130-M251 HydrophobicContact CD1-CE 4.34Å; I130-M251 HydrophobicContact CD1-SD 3.96Å; I130-M251 HydrophobicContact CG1-CE 4.14Å; I130-M251 HydrophobicContact CG1-SD 4.41Å
131L98.9Very high98.1Very high0 Ų023.1 Ų23.10%013%0.131CC..Hα-helixtrans-68.5-34.9-176.5-67.2177.7000112.3F94 I98 A127 I128 C134 E135 A217 R220 I221 E224F94-L131 HydrophobicContact CD1-CD1 4.01Å; F94-L131 HydrophobicContact CE1-CD1 3.99Å; I98-L131 HydrophobicContact CD1-CB 4Å; I98-L131 HydrophobicContact CD1-CD1 4.05Å; I98-L131 HydrophobicContact CG1-CB 3.65Å; A127-L131 WeakPolarHBondContact O-CG 3.36Å; A127-L131 PolarHBondContact O-N 3.47Å; I128-L131 PolarHBondContact O-N 2.81Å; L131-C134 PolarHBondContact O-N 3.01Å; L131-E135 PolarHBondContact O-N 3.39Å; L131-A217 HydrophobicContact CD1-CB 4.29Å; L131-R220 HydrophobicContact CD2-CB 4.27Å; L131-R220 HydrophobicContact CD2-CG 3.7Å; L131-I221 HydrophobicContact CD1-CG1 4.25Å; L131-I221 HydrophobicContact CD2-CG1 3.68Å; L131-I221 HydrophobicContact CG-CD1 4.37Å; L131-I221 HydrophobicContact CG-CG1 3.77Å; L131-E224 HydrophobicContact CD2-CG 4.32Å
132T98.9Very high98.1Very high1 Ų123.1 Ų23.11%0.00613%0.131CC..Hα-helixtrans-60.2-46.5172-61.20000111.1L102 I105 I119 I128 S129 I130 E135 R136 F140L102-T132 HydrophobicContact CD2-CG2 3.67Å; L102-T132 HydrophobicContact CG-CG2 4.01Å; I105-T132 HydrophobicContact CD1-CG2 4.11Å; I119-T132 HydrophobicContact CD1-CG2 3.85Å; I128-T132 WeakPolarHBondContact O-CB 3.35Å; I128-T132 PolarHBondContact O-N 2.68Å; I128-T132 PolarHBondContact O-OG1 2.65Å; S129-T132 PolarHBondContact O-N 2.86Å; I130-T132 PolarHBondContact O-N 3.4Å; T132-E135 PolarHBondContact O-N 2.93Å; T132-R136 PolarHBondContact O-N 3.24Å; T132-F140 HydrophobicContact CG2-CE2 4.18Å; T132-F140 HydrophobicContact CG2-CZ 3.76Å
133A98.8Very high98.1Very high0 Ų022.9 Ų22.90%013%0.13CC..Hα-helixtrans-69.1-33.2177.700000113S129 I130 E135 R136 P137 F140 V143 W230S129-A133 WeakPolarHBondContact O-CB 3.12Å; S129-A133 PolarHBondContact O-N 3.11Å; I130-A133 PolarHBondContact O-N 2.87Å; A133-E135 VanDerWaalsContact C-N 3.34Å; A133-R136 CarbonylContact O-C 3.56Å; A133-R136 PolarHBondContact O-N 2.92Å; A133-P137 WeakPolarHBondContact O-CA 3.3Å; A133-P137 VanDerWaalsContact O-N 3.11Å; A133-F140 HydrophobicContact CB-CD2 3.85Å; A133-F140 HydrophobicContact CB-CE2 4.29Å; A133-V143 HydrophobicContact CB-CG2 3.8Å; A133-W230 HydrophobicContact CB-CD2 3.9Å; A133-W230 VanDerWaalsContact CB-CE2 3.45Å; A133-W230 HydrophobicContact CB-CG 4.25Å; A133-W230 HydrophobicContact CB-CH2 4.38Å; A133-W230 HydrophobicContact CB-CZ2 3.74Å
134C98.6Very high98.2Very high19 Ų1922.1 Ų22.113%0.12813%0.125CC..Hα-helixtrans-67.7-33.2174-63.60000112.6I130 L131 R136 E224I130-C134 PolarHBondContact O-N 3.38Å; I130-C134 PolarHBondContact O-SG 3.42Å; L131-C134 PolarHBondContact O-N 3.01Å; C134-R136 VanDerWaalsContact C-N 3.31Å; C134-R136 PolarHBondContact O-N 3.05Å; C134-E224 HydrophobicContact CB-CB 4.37Å; C134-E224 HydrophobicContact CB-CG 4.26Å
135E98.6Very high98.2Very high84 Ų8422.1 Ų22.139%0.39313%0.125SC..Hα-helixtrans-71.1-27.5177.8-167.1161.1145.500112.5Q95 I98 L102 L131 T132 A133 R220Q95-E135 PolarHBondContact NE2-OE2 2.98Å; I98-E135 WeakPolarHBondContact CG2-OE2 3.33Å; L102-E135 HydrophobicContact CD1-CB 4.4Å; L102-E135 HydrophobicContact CD1-CG 4.14Å; L131-E135 PolarHBondContact O-N 3.39Å; T132-E135 PolarHBondContact O-N 2.93Å; A133-E135 VanDerWaalsContact C-N 3.34Å; E135-R220 IonicContact OE2-NH2 2.87Å
136R97.6Very high98.2Very high75 Ų7522.1 Ų22.128%0.28313%0.125SC..SBendtrans-138.373176.7-58-166.1-172169.75.5111.8L102 D106 T132 A133 C134 S138 D139 F140L102-R136 HydrophobicContact CD2-CG 4.18Å; D106-R136 IonicContact OD1-CZ 3.78Å; D106-R136 IonicContact OD1-NH1 2.71Å; D106-R136 PolarHBondContact OD1-NH1 2.85Å; D106-R136 IonicContact OD1-NH2 3.99Å; D106-R136 IonicContact OD2-CZ 3.35Å; D106-R136 IonicContact OD2-NH1 2.99Å; D106-R136 PolarHBondContact OD2-NH1 2.8Å; D106-R136 IonicContact OD2-NH2 2.8Å; D106-R136 PolarHBondContact OD2-NH2 3.01Å; T132-R136 PolarHBondContact O-N 3.24Å; A133-R136 CarbonylContact O-C 3.56Å; A133-R136 PolarHBondContact O-N 2.92Å; C134-R136 VanDerWaalsContact C-N 3.31Å; C134-R136 PolarHBondContact O-N 3.05Å; R136-S138 PolarHBondContact O-N 3.47Å; R136-D139 HydrophobicContact CB-CB 3.87Å; R136-D139 VanDerWaalsContact CD-OD2 3.23Å; R136-D139 WeakPolarHBondContact CD-OD2 3.16Å; R136-D139 IonicContact NH1-OD2 3.52Å; R136-D139 PolarHBondContact O-N 3.3Å; R136-F140 HydrophobicContact CB-CE2 4.17Å; R136-F140 WeakPolarHBondContact O-CD2 3.36Å
137P94.8Very high98.1Very high60 Ų6022.1 Ų22.139%0.3913%0.125SC..THydrogen-bonded Turntrans-65.4-16.7-168.625.4-35.1000114.8A133A133-P137 WeakPolarHBondContact O-CA 3.3Å; A133-P137 VanDerWaalsContact O-N 3.11Å
138S95.4Very high98.1Very high117 Ų11722.1 Ų22.182%0.81813%0.125SC*.THydrogen-bonded Turntrans-98.5-6.7178.7-52.30000114.1R136R136-S138 PolarHBondContact O-N 3.47Å
139D95.9Very high98Very high50 Ų5022.5 Ų22.527%0.26713%0.127SC..SBendtrans-82.1-18.3-174.5-90.114000113.3K109 R136K109-D139 IonicContact NZ-OD1 3.65Å; K109-D139 PolarHBondContact NZ-OD1 2.78Å; K109-D139 IonicContact NZ-OD2 3.67Å; K109-D139 PolarHBondContact NZ-OD2 3.05Å; R136-D139 HydrophobicContact CB-CB 3.87Å; R136-D139 VanDerWaalsContact CD-OD2 3.23Å; R136-D139 WeakPolarHBondContact CD-OD2 3.16Å; R136-D139 IonicContact NH1-OD2 3.52Å; R136-D139 PolarHBondContact O-N 3.3Å
140F98Very high97.8Very high10 Ų1022.5 Ų22.54%0.04413%0.127CC..  trans-114.9126.4-169-55.2-70.1000112L102 I105 V117 I119 T132 A133 R136 G142 V143L102-F140 HydrophobicContact CD2-CZ 4.24Å; I105-F140 HydrophobicContact CD1-CE1 3.98Å; I105-F140 HydrophobicContact CD1-CZ 4.21Å; I105-F140 HydrophobicContact CG2-CE1 4.29Å; V117-F140 HydrophobicContact CB-CD1 4.27Å; V117-F140 HydrophobicContact CG1-CD1 3.93Å; V117-F140 HydrophobicContact CG1-CE1 4.02Å; V117-F140 CarbonylContact O-C 3.57Å; V117-F140 WeakPolarHBondContact O-CA 3.23Å; I119-F140 HydrophobicContact CD1-CD1 3.76Å; I119-F140 HydrophobicContact CD1-CD2 4.45Å; I119-F140 HydrophobicContact CD1-CE1 3.59Å; I119-F140 HydrophobicContact CD1-CE2 4.29Å; I119-F140 HydrophobicContact CD1-CG 4.2Å; I119-F140 HydrophobicContact CD1-CZ 3.87Å; I119-F140 HydrophobicContact CG1-CD1 3.74Å; I119-F140 HydrophobicContact CG1-CE1 3.84Å; I119-F140 HydrophobicContact CG1-CG 4.44Å; T132-F140 HydrophobicContact CG2-CE2 4.18Å; T132-F140 HydrophobicContact CG2-CZ 3.76Å; A133-F140 HydrophobicContact CB-CD2 3.85Å; A133-F140 HydrophobicContact CB-CE2 4.29Å; R136-F140 HydrophobicContact CB-CE2 4.17Å; R136-F140 WeakPolarHBondContact O-CD2 3.36Å; F140-G142 VanDerWaalsContact C-N 3.29Å; F140-V143 HydrophobicContact CB-CG2 4.49Å
141T98.4Very high97.1Very high47 Ų4724.8 Ų24.829%0.28814%0.138SC..SBendtrans-72.7-27174.6-52.20000111.5P116 V117 F118 P231 R294P116-T141 WeakPolarHBondContact CA-OG1 3.44Å; P116-T141 HydrophobicContact CB-CG2 4.26Å; P116-T141 WeakPolarHBondContact CB-OG1 3.45Å; V117-T141 PolarHBondContact O-N 3.36Å; F118-T141 HydrophobicContact CE1-CG2 3.82Å; F118-T141 HydrophobicContact CE2-CG2 4.1Å; F118-T141 HydrophobicContact CZ-CG2 3.43Å; F118-T141 VanDerWaalsContact CZ-CG2 3.43Å; T141-P231 WeakPolarHBondContact O-CG 3.17Å; T141-R294 HydrophobicContact CG2-CB 4.39Å
142G98.6Very high96Very high0 Ų026.9 Ų26.90%015%0.148CC..EExtended strand (participates in β ladder)trans-177.1156.9172.700000113.7F118 I119 F140 P231F118-G142 VanDerWaalsContact CA-O 3.26Å; F118-G142 WeakPolarHBondContact CA-O 3.44Å; I119-G142 PolarHBondContact N-O 2.99Å; I119-G142 VanDerWaalsContact N-O 3.16Å; F140-G142 VanDerWaalsContact C-N 3.29Å; G142-P231 WeakPolarHBondContact CA-O 3.43Å
143V98.9Very high94.6Very high0 Ų027.7 Ų27.70%015%0.152CC..EExtended strand (participates in β ladder)trans-124.9123.5179.9-175.30000109.5I119 A133 F140 L145 W230 P231 F232 L233I119-V143 HydrophobicContact CB-CG1 4.42Å; I119-V143 CarbonylContact O-C 3.59Å; I119-V143 WeakPolarHBondContact O-CA 3.43Å; A133-V143 HydrophobicContact CB-CG2 3.8Å; F140-V143 HydrophobicContact CB-CG2 4.49Å; V143-L145 HydrophobicContact CG1-CD1 4.46Å; V143-L145 HydrophobicContact CG1-CD2 3.77Å; V143-L145 HydrophobicContact CG1-CG 3.96Å; V143-W230 HydrophobicContact CB-CE3 3.81Å; V143-W230 HydrophobicContact CB-CH2 4.31Å; V143-W230 HydrophobicContact CB-CZ3 3.51Å; V143-W230 HydrophobicContact CG1-CH2 4.36Å; V143-W230 HydrophobicContact CG1-CZ3 3.99Å; V143-W230 HydrophobicContact CG2-CD2 4.15Å; V143-W230 HydrophobicContact CG2-CE3 3.55Å; V143-W230 HydrophobicContact CG2-CH2 4.34Å; V143-W230 HydrophobicContact CG2-CZ3 3.67Å; V143-P231 PolarHBondContact N-O 3.28Å; V143-F232 HydrophobicContact CB-CB 4.46Å; V143-F232 CarbonylContact O-C 3.59Å; V143-F232 WeakPolarHBondContact O-CA 3.39Å; V143-F232 VanDerWaalsContact O-CB 3.3Å; V143-F232 WeakPolarHBondContact O-CB 3.26Å; V143-L233 PolarHBondContact O-N 3.12Å
144V98.9Very high92.9Very high0 Ų030.2 Ų30.20%017%0.168CC..EExtended strand (participates in β ladder)trans-105.3129.5176.1-176.90000109.3I119 V120 G121 L233 V287 W290 I291I119-V144 PolarHBondContact O-N 3.44Å; V120-V144 CarbonylContact C-O 3.19Å; V120-V144 WeakPolarHBondContact CA-O 3.35Å; V120-V144 HydrophobicContact CG1-CB 4.46Å; V120-V144 HydrophobicContact CG2-CB 4.19Å; G121-V144 PolarHBondContact N-O 2.97Å; V144-L233 HydrophobicContact CG1-CB 4.23Å; V144-L233 HydrophobicContact CG1-CD2 3.93Å; V144-L233 HydrophobicContact CG1-CG 4.3Å; V144-L233 HydrophobicContact CG2-CB 4.27Å; V144-V287 HydrophobicContact CG1-CB 4.43Å; V144-V287 HydrophobicContact CG1-CG1 4.26Å; V144-V287 HydrophobicContact CG1-CG2 3.85Å; V144-W290 HydrophobicContact CG2-CD2 4.39Å; V144-W290 HydrophobicContact CG2-CE3 3.59Å; V144-W290 HydrophobicContact CG2-CZ3 3.87Å; V144-I291 HydrophobicContact CG2-CD1 4.05Å; V144-I291 HydrophobicContact CG2-CG1 3.88Å
145L98.9Very high91.3Very high0 Ų036.6 Ų36.60%020%0.196CC..EExtended strand (participates in β ladder)trans-128.4119.2-169.8-63.5172.8000109.8G121 G126 I130 V143 P148 L233 L234 L235 M251G121-L145 WeakPolarHBondContact O-CA 3.44Å; G126-L145 WeakPolarHBondContact O-CD2 3.41Å; I130-L145 HydrophobicContact CD1-CD1 3.99Å; I130-L145 HydrophobicContact CD1-CD2 4.42Å; I130-L145 HydrophobicContact CG1-CD1 3.74Å; I130-L145 HydrophobicContact CG1-CD2 3.97Å; V143-L145 HydrophobicContact CG1-CD1 4.46Å; V143-L145 HydrophobicContact CG1-CD2 3.77Å; V143-L145 HydrophobicContact CG1-CG 3.96Å; L145-P148 HydrophobicContact CB-CB 4.12Å; L145-P148 HydrophobicContact CB-CG 3.94Å; L145-P148 HydrophobicContact CD2-CB 4.39Å; L145-L233 PolarHBondContact N-O 3.25Å; L145-L234 HydrophobicContact CB-CD2 3.72Å; L145-L234 HydrophobicContact CD1-CD2 3.61Å; L145-L234 HydrophobicContact CD1-CG 4.39Å; L145-L234 HydrophobicContact CG-CD2 4.32Å; L145-L235 PolarHBondContact O-N 3.47Å; L145-M251 HydrophobicContact CD1-CE 3.75Å; L145-M251 HydrophobicContact CD1-SD 4.05Å
146I98.8Very high89.5Confident0 Ų035.8 Ų35.80%020%0.2CC..EExtended strand (participates in β ladder)trans-112.9107.3-177.4-49.3176000108.8I62 V120 G121 H122 S123 L235 L272 H273 V283 V287I62-I146 HydrophobicContact CD1-CD1 4.01Å; V120-I146 HydrophobicContact CG1-CD1 4.27Å; G121-I146 PolarHBondContact O-N 2.88Å; H122-I146 WeakPolarHBondContact CA-O 3.28Å; H122-I146 HydrophobicContact CB-CB 4.27Å; H122-I146 PolarHBondContact ND1-O 2.58Å; S123-I146 PolarHBondContact N-O 3.14Å; I146-L235 HydrophobicContact CG1-CD1 4.42Å; I146-L272 HydrophobicContact CG2-CB 3.88Å; I146-L272 HydrophobicContact CG2-CD1 4.36Å; I146-L272 HydrophobicContact CG2-CG 4.47Å; I146-H273 HydrophobicContact CD1-CB 4.35Å; I146-V283 HydrophobicContact CD1-CG1 4.26Å; I146-V287 HydrophobicContact CD1-CG2 4.1Å
147G97.6Very high87.7Confident0 Ų032.6 Ų32.60%019%0.19CC..SBendtrans51.450.7-174.800000113S123 L235S123-G147 VanDerWaalsContact CA-O 3.24Å; S123-G147 WeakPolarHBondContact CA-O 3.32Å; S123-G147 PolarHBondContact N-O 3.47Å; G147-L235 PolarHBondContact N-O 3.18Å
148P98.4Very high86.1Confident1 Ų133.7 Ų33.71%0.00620%0.196CC..  trans-68.9146.1-171.531.1-38.3000112.4I130 L145 V150 L234I130-P148 HydrophobicContact CD1-CB 4.31Å; L145-P148 HydrophobicContact CB-CB 4.12Å; L145-P148 HydrophobicContact CB-CG 3.94Å; L145-P148 HydrophobicContact CD2-CB 4.39Å; P148-V150 HydrophobicContact CB-CG2 4.26Å; P148-V150 HydrophobicContact CG-CG2 4.09Å; P148-V150 PolarHBondContact O-N 3.49Å; P148-L234 HydrophobicContact CG-CD2 3.62Å
149M96.6Very high84.4Confident8 Ų832.1 Ų32.14%0.03918%0.182CC..  trans-76.568.2174.5-169.6-168.87400111.7S123 A127 M152 L214 A217 C243S123-M149 WeakPolarHBondContact O-CB 3.15Å; S123-M149 PolarHBondContact O-N 3.15Å; A127-M149 HydrophobicContact CB-CB 4.21Å; A127-M149 HydrophobicContact CB-CE 3.83Å; M149-M152 HydrophobicContact CG-CG 4.23Å; M149-M152 HydrophobicContact SD-CG 4.4Å; M149-L214 HydrophobicContact CE-CB 4.01Å; M149-L214 HydrophobicContact CE-CD2 3.9Å; M149-L214 WeakPolarHBondContact CE-O 3.49Å; M149-L214 HydrophobicContact SD-CB 3.94Å; M149-L214 HydrophobicContact SD-CD1 4.4Å; M149-L214 HydrophobicContact SD-CD2 3.96Å; M149-L214 HydrophobicContact SD-CG 4.31Å; M149-A217 HydrophobicContact CE-CB 4.2Å; M149-C243 VanDerWaalsContact CA-SG 3.59Å
150V94.6Very high82.8Confident0 Ų030.4 Ų30.40%017%0.172CC..SBendtrans-80.6-43.9171178.50000110.4I130 P148 I221 I225 G247 M250 M251I130-V150 HydrophobicContact CD1-CG2 3.75Å; P148-V150 HydrophobicContact CB-CG2 4.26Å; P148-V150 HydrophobicContact CG-CG2 4.09Å; P148-V150 PolarHBondContact O-N 3.49Å; V150-I221 HydrophobicContact CB-CG2 4.49Å; V150-I221 HydrophobicContact CG1-CG2 3.93Å; V150-I221 HydrophobicContact CG2-CG2 4.4Å; V150-I225 HydrophobicContact CG1-CD1 4.07Å; V150-G247 WeakPolarHBondContact CG1-O 3.43Å; V150-M250 HydrophobicContact CG1-CE 4.09Å; V150-M251 HydrophobicContact CG1-CB 4.46Å; V150-M251 HydrophobicContact CG2-SD 4.11Å
151Q84.1Confident81.1Confident49 Ų4935.3 Ų35.323%0.22919%0.194CC..SBendtrans-134.5136.1172.1-73.7-172.9-32.200109.3E222 D244 M250Q151-E222 WeakPolarHBondContact CG-OE1 3.3Å; Q151-E222 PolarHBondContact NE2-OE1 3.27Å; Q151-D244 PolarHBondContact O-N 2.85Å; Q151-M250 HydrophobicContact CG-CE 3.97Å
152M74.8Confident79.3Confident44 Ų4436.6 Ų36.622%0.21720%0.202CC..BIsolated β-bridgetrans-78.9144.1171.7-58.2179.772.100109.3M149 P154 A157 L214 M215M149-M152 HydrophobicContact CG-CG 4.23Å; M149-M152 HydrophobicContact SD-CG 4.4Å; M152-P154 WeakPolarHBondContact O-CD 3.41Å; M152-A157 HydrophobicContact CB-CB 4.44Å; M152-L214 HydrophobicContact SD-CB 4.23Å; M152-M215 HydrophobicContact SD-CG 3.91Å
153N70.2Confident77.6Confident18 Ų1840.2 Ų40.210%0.09622%0.217CC..  trans-55.2123.4177.9-172.4-36.1000111.3E155 S156 A157 K241 L242N153-E155 VanDerWaalsContact C-N 3.25Å; N153-E155 PolarHBondContact O-N 2.93Å; N153-E155 PolarHBondContact OD1-N 2.85Å; N153-S156 PolarHBondContact O-N 3.2Å; N153-A157 VanDerWaalsContact O-CB 3.32Å; N153-A157 WeakPolarHBondContact O-CB 3.37Å; N153-A157 PolarHBondContact O-N 3.47Å; N153-K241 PolarHBondContact ND2-O 3.44Å; N153-L242 PolarHBondContact N-O 3.28Å
154P63.7Low75.9Confident52 Ų5241 Ų4134%0.33822%0.222SC..Hα-helixtrans-58.1-30.1-179.4-30.339.9000115.1M152 S156 A157 T158 D244 R246M152-P154 WeakPolarHBondContact O-CD 3.41Å; P154-S156 VanDerWaalsContact C-N 3.32Å; P154-A157 PolarHBondContact O-N 2.89Å; P154-T158 VanDerWaalsContact O-CB 3.28Å; P154-T158 WeakPolarHBondContact O-CB 3.19Å; P154-T158 PolarHBondContact O-N 3.21Å; P154-T158 PolarHBondContact O-OG1 2.92Å; P154-D244 WeakPolarHBondContact CD-OD2 3.28Å; P154-R246 VanDerWaalsContact CD-NH2 3.29Å; P154-R246 VanDerWaalsContact CG-NH2 3.28Å
155E64.2Low74.1Confident153 Ų15343.7 Ų43.772%0.71525%0.245SC*.Hα-helixtrans-67.2-35.3176.6-67-172.9170.400111.5N153 P159N153-E155 VanDerWaalsContact C-N 3.25Å; N153-E155 PolarHBondContact O-N 2.93Å; N153-E155 PolarHBondContact OD1-N 2.85Å; E155-P159 WeakPolarHBondContact O-CD 3.39Å; E155-P159 WeakPolarHBondContact O-CG 3.28Å
156S60.6Low72.1Confident68 Ų6850.7 Ų50.748%0.47628%0.275SS..Hα-helixtrans-80.8-36.3172.7-48.10000111.8N153 P154 F160N153-S156 PolarHBondContact O-N 3.2Å; P154-S156 VanDerWaalsContact C-N 3.32Å; S156-F160 WeakPolarHBondContact O-CB 3.45Å; S156-F160 PolarHBondContact O-N 3.2Å
157A60.3Low70.2Confident7 Ų751.6 Ų51.66%0.05828%0.28CS..Hα-helixtrans-75.7-28-17600000113.1M152 N153 P154 K161M152-A157 HydrophobicContact CB-CB 4.44Å; N153-A157 VanDerWaalsContact O-CB 3.32Å; N153-A157 WeakPolarHBondContact O-CB 3.37Å; N153-A157 PolarHBondContact O-N 3.47Å; P154-A157 PolarHBondContact O-N 2.89Å; A157-K161 VanDerWaalsContact O-CB 3.23Å; A157-K161 WeakPolarHBondContact O-CB 3.41Å; A157-K161 WeakPolarHBondContact O-CG 3.42Å; A157-K161 PolarHBondContact O-N 3.35Å
158T60.7Low68.3Low84 Ų8457.2 Ų57.252%0.51531%0.309SS..Hα-helixtrans-71.3-49.5-178.3-56.30000112.3P154 F160 K161 V162P154-T158 VanDerWaalsContact O-CB 3.28Å; P154-T158 WeakPolarHBondContact O-CB 3.19Å; P154-T158 PolarHBondContact O-N 3.21Å; P154-T158 PolarHBondContact O-OG1 2.92Å; T158-F160 VanDerWaalsContact C-N 3.29Å; T158-F160 PolarHBondContact O-N 2.74Å; T158-K161 PolarHBondContact O-N 2.94Å; T158-V162 WeakPolarHBondContact O-CG2 3.33Å; T158-V162 PolarHBondContact O-N 3.41Å
159P59.8Low66.2Low83 Ų8364.1 Ų64.154%0.53935%0.346SS..Hα-helixtrans-59-40.6170.3-23.134.4000112.2E155 V162 F163E155-P159 WeakPolarHBondContact O-CD 3.39Å; E155-P159 WeakPolarHBondContact O-CG 3.28Å; P159-V162 PolarHBondContact O-N 3.39Å; P159-F163 WeakPolarHBondContact O-CB 3.17Å; P159-F163 PolarHBondContact O-N 3.38Å
160F62.3Low64.1Low14 Ų1470.3 Ų70.36%0.06137%0.374CS..Hα-helixtrans-58.8-51.6175.6-176.7-80.5000111.7S156 T158 V162 F163 V164 L177 L206 G211 M215S156-F160 WeakPolarHBondContact O-CB 3.45Å; S156-F160 PolarHBondContact O-N 3.2Å; T158-F160 VanDerWaalsContact C-N 3.29Å; T158-F160 PolarHBondContact O-N 2.74Å; F160-V162 PolarHBondContact O-N 3.36Å; F160-F163 WeakPolarHBondContact O-CB 3.07Å; F160-F163 PolarHBondContact O-N 3.46Å; F160-V164 HydrophobicContact CD1-CG2 3.86Å; F160-V164 HydrophobicContact CE1-CG2 3.4Å; F160-V164 VanDerWaalsContact CE1-CG2 3.4Å; F160-V164 HydrophobicContact CZ-CG2 3.84Å; F160-V164 WeakPolarHBondContact O-CG2 3.29Å; F160-V164 PolarHBondContact O-N 3.44Å; F160-L177 HydrophobicContact CD2-CD1 3.17Å; F160-L177 HydrophobicContact CD2-CD2 4.34Å; F160-L177 HydrophobicContact CD2-CG 4.32Å; F160-L177 HydrophobicContact CE2-CD1 2.96Å; F160-L177 HydrophobicContact CE2-CG 4.39Å; F160-L177 HydrophobicContact CG-CD1 4.3Å; F160-L177 HydrophobicContact CZ-CD1 3.96Å; F160-L206 HydrophobicContact CE2-CD2 4.21Å; F160-G211 VanDerWaalsContact CZ-CA 3.41Å; F160-M215 HydrophobicContact CD1-SD 3.51Å; F160-M215 VanDerWaalsContact CD1-SD 3.51Å; F160-M215 HydrophobicContact CE1-CG 4.19Å; F160-M215 HydrophobicContact CE1-SD 3.37Å; F160-M215 WeakPolarHBondContact CE1-SD 3.44Å
161K62.9Low62.4Low113 Ų11377.9 Ų77.949%0.49141%0.412SS..Hα-helixtrans-61-42.3179.4-79.1172.8178.8-177.50112.2A157 T158 F163 V164 A165 M215A157-K161 VanDerWaalsContact O-CB 3.23Å; A157-K161 WeakPolarHBondContact O-CB 3.41Å; A157-K161 WeakPolarHBondContact O-CG 3.42Å; A157-K161 PolarHBondContact O-N 3.35Å; T158-K161 PolarHBondContact O-N 2.94Å; K161-F163 VanDerWaalsContact C-N 3.34Å; K161-V164 PolarHBondContact O-N 3.44Å; K161-A165 VanDerWaalsContact O-CB 3.3Å; K161-A165 WeakPolarHBondContact O-CB 3.46Å; K161-A165 PolarHBondContact O-N 2.86Å; K161-M215 HydrophobicContact CD-CE 4.27Å; K161-M215 VanDerWaalsContact CE-CE 3.46Å; K161-M215 HydrophobicContact CG-CE 3.84Å; K161-M215 HydrophobicContact CG-SD 4.12Å
162V61.1Low61.4Low75 Ų7579.6 Ų79.646%0.45542%0.422SS..Hα-helixtrans-64.5-40176.1171.80000111.2T158 P159 F160 K166T158-V162 WeakPolarHBondContact O-CG2 3.33Å; T158-V162 PolarHBondContact O-N 3.41Å; P159-V162 PolarHBondContact O-N 3.39Å; F160-V162 PolarHBondContact O-N 3.36Å; V162-K166 HydrophobicContact CG1-CD 4.42Å; V162-K166 WeakPolarHBondContact O-CG 3.46Å; V162-K166 PolarHBondContact O-N 3Å; V162-K166 VanDerWaalsContact O-N 3.08Å
163F62.6Low60.9Low75 Ų7581.8 Ų81.833%0.32944%0.44SS..Hα-helixtrans-66.4-46.2176.6-172.3-102000112P159 F160 K161 A165 K166 L167 L175 L177 V208P159-F163 WeakPolarHBondContact O-CB 3.17Å; P159-F163 PolarHBondContact O-N 3.38Å; F160-F163 WeakPolarHBondContact O-CB 3.07Å; F160-F163 PolarHBondContact O-N 3.46Å; K161-F163 VanDerWaalsContact C-N 3.34Å; F163-A165 PolarHBondContact O-N 3.39Å; F163-K166 PolarHBondContact O-N 3.39Å; F163-L167 WeakPolarHBondContact O-CB 3.48Å; F163-L167 PolarHBondContact O-N 3.44Å; F163-L175 HydrophobicContact CE1-CB 4.15Å; F163-L175 HydrophobicContact CE1-CD1 4.21Å; F163-L175 HydrophobicContact CZ-CB 4.2Å; F163-L175 HydrophobicContact CZ-CD1 3.71Å; F163-L177 HydrophobicContact CB-CD2 4.21Å; F163-L177 HydrophobicContact CD1-CD2 3.51Å; F163-L177 HydrophobicContact CD1-CG 4.19Å; F163-L177 HydrophobicContact CE1-CD2 3.98Å; F163-L177 HydrophobicContact CE1-CG 4.32Å; F163-L177 HydrophobicContact CG-CD2 3.93Å; F163-V208 HydrophobicContact CD1-CG2 3.81Å; F163-V208 HydrophobicContact CE1-CG2 3.5Å; F163-V208 VanDerWaalsContact CE1-CG2 3.5Å
164V62.9Low60.7Low17 Ų1785.1 Ų85.110%0.10346%0.464CS..Hα-helixtrans-59.4-44.9174.5172.30000111.3F160 K161 K166 L167 L168 V208 I212F160-V164 HydrophobicContact CD1-CG2 3.86Å; F160-V164 HydrophobicContact CE1-CG2 3.4Å; F160-V164 VanDerWaalsContact CE1-CG2 3.4Å; F160-V164 HydrophobicContact CZ-CG2 3.84Å; F160-V164 WeakPolarHBondContact O-CG2 3.29Å; F160-V164 PolarHBondContact O-N 3.44Å; K161-V164 PolarHBondContact O-N 3.44Å; V164-K166 VanDerWaalsContact C-N 3.3Å; V164-K166 PolarHBondContact O-N 2.87Å; V164-L167 CarbonylContact O-C 3.57Å; V164-L167 WeakPolarHBondContact O-CB 3.32Å; V164-L167 PolarHBondContact O-N 3.18Å; V164-L168 HydrophobicContact CG1-CD1 3.94Å; V164-L168 HydrophobicContact CG1-CG 4.21Å; V164-L168 WeakPolarHBondContact O-CG 3.44Å; V164-L168 PolarHBondContact O-N 3.13Å; V164-V208 HydrophobicContact CG2-CG1 3.76Å; V164-I212 HydrophobicContact CG1-CD1 4.19Å; V164-I212 HydrophobicContact CG1-CG1 4.21Å; V164-I212 HydrophobicContact CG2-CG1 4.34Å
165A60.8Low61.2Low57 Ų5785.8 Ų85.847%0.47147%0.465SS..Hα-helixtrans-60.4-40.1177.600000112.1K161 F163 L167 N169K161-A165 VanDerWaalsContact O-CB 3.3Å; K161-A165 WeakPolarHBondContact O-CB 3.46Å; K161-A165 PolarHBondContact O-N 2.86Å; F163-A165 PolarHBondContact O-N 3.39Å; A165-L167 VanDerWaalsContact C-N 3.33Å; A165-N169 PolarHBondContact O-N 3.49Å
166K57.6Low61.5Low147 Ų14781.1 Ų81.164%0.63945%0.447SS*.Hα-helixtrans-67.6-32.9173.8-73.3177.7179-1780112.6V162 F163 V164 N169 H170V162-K166 HydrophobicContact CG1-CD 4.42Å; V162-K166 WeakPolarHBondContact O-CG 3.46Å; V162-K166 PolarHBondContact O-N 3Å; V162-K166 VanDerWaalsContact O-N 3.08Å; F163-K166 PolarHBondContact O-N 3.39Å; V164-K166 VanDerWaalsContact C-N 3.3Å; V164-K166 PolarHBondContact O-N 2.87Å; K166-N169 WeakPolarHBondContact O-CB 3.39Å; K166-N169 PolarHBondContact O-N 3.49Å; K166-H170 PolarHBondContact O-N 3.49Å
167L59.1Low61.7Low18 Ų1879.2 Ų79.29%0.09443%0.431CS..Hα-helixtrans-76.3-35.1178.1-16766.9000113.5F163 V164 A165 N169 H170 M171 L172 L175 V208F163-L167 WeakPolarHBondContact O-CB 3.48Å; F163-L167 PolarHBondContact O-N 3.44Å; V164-L167 CarbonylContact O-C 3.57Å; V164-L167 WeakPolarHBondContact O-CB 3.32Å; V164-L167 PolarHBondContact O-N 3.18Å; A165-L167 VanDerWaalsContact C-N 3.33Å; L167-N169 PolarHBondContact O-N 3.48Å; L167-H170 WeakPolarHBondContact CD1-O 3.37Å; L167-H170 CarbonylContact O-C 3.59Å; L167-H170 WeakPolarHBondContact O-CA 3.46Å; L167-H170 PolarHBondContact O-N 3.36Å; L167-M171 PolarHBondContact O-N 3.1Å; L167-L172 HydrophobicContact CD1-CB 3.66Å; L167-L172 WeakPolarHBondContact CD1-O 3.32Å; L167-L172 WeakPolarHBondContact CD2-O 3.49Å; L167-L175 HydrophobicContact CD1-CD1 3.3Å; L167-L175 HydrophobicContact CD1-CG 4.08Å; L167-V208 HydrophobicContact CD2-CB 3.86Å; L167-V208 HydrophobicContact CD2-CG1 3.47Å; L167-V208 VanDerWaalsContact CD2-CG1 3.47Å; L167-V208 HydrophobicContact CD2-CG2 3.96Å
168L57.4Low61.9Low118 Ų11881.1 Ų81.162%0.61845%0.451SS*.Hα-helixtrans-64-26.1172.7-70.5171.3000111V164 H170V164-L168 HydrophobicContact CG1-CD1 3.94Å; V164-L168 HydrophobicContact CG1-CG 4.21Å; V164-L168 WeakPolarHBondContact O-CG 3.44Å; V164-L168 PolarHBondContact O-N 3.13Å; L168-H170 VanDerWaalsContact C-N 3.28Å
169N54.1Low62.2Low146 Ų14680.6 Ų80.678%0.78145%0.451SS*.THydrogen-bonded Turntrans-74.6-10.4166.6-93-5.2000114.3A165 K166 L167A165-N169 PolarHBondContact O-N 3.49Å; K166-N169 WeakPolarHBondContact O-CB 3.39Å; K166-N169 PolarHBondContact O-N 3.49Å; L167-N169 PolarHBondContact O-N 3.48Å
170H52.3Low62.6Low138 Ų13880.5 Ų80.564%0.63945%0.445SS*.THydrogen-bonded Turntrans-146.784.8-176.8-118.955.3000110.5K166 L167 L168 L172K166-H170 PolarHBondContact O-N 3.49Å; L167-H170 WeakPolarHBondContact CD1-O 3.37Å; L167-H170 CarbonylContact O-C 3.59Å; L167-H170 WeakPolarHBondContact O-CA 3.46Å; L167-H170 PolarHBondContact O-N 3.36Å; L168-H170 VanDerWaalsContact C-N 3.28Å; H170-L172 VanDerWaalsContact C-N 3.35Å; H170-L172 PolarHBondContact O-N 2.68Å
171M58.8Low63.2Low159 Ų15984.4 Ų84.478%0.78346%0.464SS*.THydrogen-bonded Turntrans-44.573.9-171.4-59.2-109.485.600116.6L167L167-M171 PolarHBondContact O-N 3.1Å
172L64Low64Low85 Ų8580 Ų8045%0.44545%0.447SS..  trans-132.872.6-176.8-65.3169.4000112.4L167 H170 S174 L175L167-L172 HydrophobicContact CD1-CB 3.66Å; L167-L172 WeakPolarHBondContact CD1-O 3.32Å; L167-L172 WeakPolarHBondContact CD2-O 3.49Å; H170-L172 VanDerWaalsContact C-N 3.35Å; H170-L172 PolarHBondContact O-N 2.68Å; L172-S174 PolarHBondContact O-N 3.19Å; L172-S174 VanDerWaalsContact O-N 3.1Å; L172-L175 HydrophobicContact CB-CD1 4.38Å; L172-L175 HydrophobicContact CB-CG 4.2Å; L172-L175 PolarHBondContact O-N 3Å
173P62.6Low65Low90 Ų9081.6 Ų81.658%0.58445%0.448SS*.THydrogen-bonded Turntrans-65.2-14.4-174.326.3-35000115.3
174S66.9Low66Low88 Ų8881.9 Ų81.962%0.61545%0.447SS*.THydrogen-bonded Turntrans-85.30.9-178.859.90000114.8L172L172-S174 PolarHBondContact O-N 3.19Å; L172-S174 VanDerWaalsContact O-N 3.1Å
175L74.1Confident67.1Low67 Ų6782 Ų8235%0.35145%0.448SS..  trans-66.3147.9175.9-70.3-175.5000111.7F163 L167 L172 V208F163-L175 HydrophobicContact CE1-CB 4.15Å; F163-L175 HydrophobicContact CE1-CD1 4.21Å; F163-L175 HydrophobicContact CZ-CB 4.2Å; F163-L175 HydrophobicContact CZ-CD1 3.71Å; L167-L175 HydrophobicContact CD1-CD1 3.3Å; L167-L175 HydrophobicContact CD1-CG 4.08Å; L172-L175 HydrophobicContact CB-CD1 4.38Å; L172-L175 HydrophobicContact CB-CG 4.2Å; L172-L175 PolarHBondContact O-N 3Å; L175-V208 HydrophobicContact CB-CG2 4.2Å; L175-V208 WeakPolarHBondContact O-CG2 3.48Å; L175-V208 PolarHBondContact O-N 3.25Å
176T70.3Confident68.7Low55 Ų5579.5 Ų79.534%0.33743%0.427SS..BIsolated β-bridgetrans-116.2141.4-179.763.40000111.4R205 L206 R207T176-R205 VanDerWaalsContact CB-CB 3.5Å; T176-R205 HydrophobicContact CG2-CB 4.15Å; T176-L206 CarbonylContact C-O 3.53Å; T176-L206 WeakPolarHBondContact CA-O 3.33Å; T176-R207 HydrophobicContact CG2-CG 4.15Å
177L65.1Low70.5Confident27 Ų2775.9 Ų75.914%0.14141%0.409CS..  trans-91.9-169177.1-70.8150.5000111.1F160 F163 R205 L206 V208F160-L177 HydrophobicContact CD2-CD1 3.17Å; F160-L177 HydrophobicContact CD2-CD2 4.34Å; F160-L177 HydrophobicContact CD2-CG 4.32Å; F160-L177 HydrophobicContact CE2-CD1 2.96Å; F160-L177 HydrophobicContact CE2-CG 4.39Å; F160-L177 HydrophobicContact CG-CD1 4.3Å; F160-L177 HydrophobicContact CZ-CD1 3.96Å; F163-L177 HydrophobicContact CB-CD2 4.21Å; F163-L177 HydrophobicContact CD1-CD2 3.51Å; F163-L177 HydrophobicContact CD1-CG 4.19Å; F163-L177 HydrophobicContact CE1-CD2 3.98Å; F163-L177 HydrophobicContact CE1-CG 4.32Å; F163-L177 HydrophobicContact CG-CD2 3.93Å; L177-R205 VanDerWaalsContact O-CB 3.29Å; L177-R205 WeakPolarHBondContact O-CB 3.48Å; L177-R205 PolarHBondContact O-NE 3.46Å; L177-R205 PolarHBondContact O-NH2 3.27Å; L177-L206 HydrophobicContact CB-CB 4.43Å; L177-L206 PolarHBondContact N-O 3.06Å; L177-V208 HydrophobicContact CD1-CG2 3.89Å; L177-V208 HydrophobicContact CG-CG2 4.05Å
178G64.6Low72.2Confident47 Ų4776.2 Ų76.249%0.48541%0.411SS..PPolyproline II helixtrans-57.1163.6173.100000112.8L206G178-L206 PolarHBondContact O-N 2.79Å
179S65.9Low74Confident74 Ų7478.4 Ų78.452%0.51742%0.418SS..PPolyproline II helixtrans-82.3155.9163.5490000109.7
180I69.8Low76Confident80 Ų8075.5 Ų75.541%0.4141%0.406SS..PPolyproline II helixtrans-68.8129.2164.8-63.5174.1000106.2S182 V185 L242I180-S182 PolarHBondContact O-N 3.43Å; I180-V185 HydrophobicContact CG2-CG2 4.25Å; I180-L242 HydrophobicContact CG2-CD1 3.89Å; I180-L242 HydrophobicContact CG2-CD2 4.06Å
181E74.6Confident78Confident96 Ų9672.1 Ų72.145%0.44939%0.39SS..PPolyproline II helixtrans-81.1118.8170.9-45.7174.7-116.500107.9K183 W184E181-K183 HydrophobicContact CB-CD 4.45Å; E181-K183 HydrophobicContact CB-CG 4.11Å; E181-K183 PolarHBondContact O-N 3.19Å; E181-K183 VanDerWaalsContact O-N 3.12Å; E181-K183 WeakPolarHBondContact OE2-CE 3.39Å; E181-K183 IonicContact OE2-NZ 3.2Å; E181-K183 PolarHBondContact OE2-NZ 2.95Å; E181-W184 WeakPolarHBondContact O-CB 3.48Å; E181-W184 PolarHBondContact O-N 3.49Å; E181-W184 PolarHBondContact OE1-NE1 3.32Å
182S79.8Confident79.7Confident20 Ų2065.7 Ų65.714%0.1436%0.36CS..G310 helixtrans-54.1-31.5-17754.10000113.1I180 W184 V185 D196I180-S182 PolarHBondContact O-N 3.43Å; S182-W184 PolarHBondContact O-N 2.92Å; S182-V185 WeakPolarHBondContact O-CB 3.38Å; S182-V185 WeakPolarHBondContact O-CG2 3.24Å; S182-V185 PolarHBondContact O-N 2.77Å; S182-D196 WeakPolarHBondContact CB-OD1 3.37Å; S182-D196 VanDerWaalsContact OG-CG 3.31Å; S182-D196 PolarHBondContact OG-OD1 2.91Å; S182-D196 PolarHBondContact OG-OD2 2.92Å
183K80.9Confident81.2Confident109 Ų10967.6 Ų67.647%0.47437%0.366SS..G310 helixtrans-57.7-18.1173.679.6-170.9-167.4-159.50115.3E181 Y269E181-K183 HydrophobicContact CB-CD 4.45Å; E181-K183 HydrophobicContact CB-CG 4.11Å; E181-K183 PolarHBondContact O-N 3.19Å; E181-K183 VanDerWaalsContact O-N 3.12Å; E181-K183 WeakPolarHBondContact OE2-CE 3.39Å; E181-K183 IonicContact OE2-NZ 3.2Å; E181-K183 PolarHBondContact OE2-NZ 2.95Å; K183-Y269 WeakPolarHBondContact O-CE2 3.39Å
184W83.7Confident82.7Confident81 Ų8165.9 Ų65.931%0.30736%0.36SS..G310 helixtrans-87.8-11.3175.5-60.5123000112.6E181 S182 K241E181-W184 WeakPolarHBondContact O-CB 3.48Å; E181-W184 PolarHBondContact O-N 3.49Å; E181-W184 PolarHBondContact OE1-NE1 3.32Å; S182-W184 PolarHBondContact O-N 2.92Å; W184-K241 HydrophobicContact CB-CB 4.39Å; W184-K241 HydrophobicContact CD2-CB 4.33Å; W184-K241 HydrophobicContact CD2-CG 4.18Å; W184-K241 HydrophobicContact CE3-CB 4.17Å; W184-K241 HydrophobicContact CE3-CG 3.55Å; W184-K241 HydrophobicContact CG-CB 4.44Å; W184-K241 HydrophobicContact CZ3-CG 3.89Å
185V86.5Confident83.9Confident20 Ų2063.6 Ų63.612%0.12134%0.338CS..THydrogen-bonded Turntrans-79.7-44.6-176.5-179.60000110.7I180 S182 L242 H270 A271I180-V185 HydrophobicContact CG2-CG2 4.25Å; S182-V185 WeakPolarHBondContact O-CB 3.38Å; S182-V185 WeakPolarHBondContact O-CG2 3.24Å; S182-V185 PolarHBondContact O-N 2.77Å; V185-L242 HydrophobicContact CG2-CD1 4.2Å; V185-H270 PolarHBondContact O-N 2.79Å; V185-A271 HydrophobicContact CG1-CB 3.5Å; V185-A271 PolarHBondContact O-N 3.36Å
186S93.8Very high84.9Confident5 Ų563.8 Ų63.84%0.03534%0.34CS..  trans-142.2154.2-177.8179.40000111.5D188 H274 D275S186-D188 PolarHBondContact OG-N 3.13Å; S186-H274 VanDerWaalsContact CB-O 3.3Å; S186-H274 WeakPolarHBondContact CB-O 3.21Å; S186-H274 PolarHBondContact OG-O 3.41Å; S186-D275 WeakPolarHBondContact OG-CA 3.2Å
187R95.5Very high86.1Confident70 Ų7066.5 Ų66.526%0.26435%0.352SS..SBendtrans-85.7-19.1167.4-63.1171.7-69.4175.1-3.4112.5E189 G267 Y269 D275 L276R187-E189 PolarHBondContact O-N 2.8Å; R187-G267 WeakPolarHBondContact CD-O 3.43Å; R187-G267 PolarHBondContact NE-O 2.69Å; R187-G267 PolarHBondContact NH1-O 3.13Å; R187-G267 VanDerWaalsContact NH1-O 3.09Å; R187-Y269 HydrophobicContact CG-CD1 3.51Å; R187-Y269 HydrophobicContact CG-CD2 3.67Å; R187-Y269 HydrophobicContact CG-CE1 3.53Å; R187-Y269 HydrophobicContact CG-CE2 3.67Å; R187-Y269 HydrophobicContact CG-CG 3.59Å; R187-D275 WeakPolarHBondContact CB-OD1 3.11Å; R187-D275 IonicContact CZ-OD1 3.87Å; R187-D275 IonicContact CZ-OD2 3.45Å; R187-D275 PolarHBondContact N-OD1 3.23Å; R187-D275 IonicContact NE-OD1 2.64Å; R187-D275 PolarHBondContact NE-OD1 2.72Å; R187-D275 IonicContact NE-OD2 2.82Å; R187-D275 PolarHBondContact NE-OD2 3.45Å; R187-D275 IonicContact NH2-OD1 3.94Å; R187-D275 PolarHBondContact NH2-OD1 3.35Å; R187-D275 IonicContact NH2-OD2 3.61Å; R187-D275 PolarHBondContact NH2-OD2 2.97Å; R187-L276 HydrophobicContact CB-CD2 3.92Å; R187-L276 HydrophobicContact CB-CG 4.01Å
188D95.9Very high87.6Confident25 Ų2567.2 Ų67.213%0.13436%0.356CS..  trans-79109.2177-172-22000109.4S186 T190 Q191 V192 L276S186-D188 PolarHBondContact OG-N 3.13Å; D188-T190 VanDerWaalsContact CG-OG1 3.24Å; D188-T190 PolarHBondContact O-N 2.74Å; D188-T190 WeakPolarHBondContact OD1-CB 3.4Å; D188-T190 PolarHBondContact OD1-N 2.92Å; D188-T190 PolarHBondContact OD1-OG1 2.83Å; D188-T190 PolarHBondContact OD2-OG1 3.23Å; D188-Q191 HydrophobicContact CB-CB 4.16Å; D188-Q191 HydrophobicContact CB-CG 3.89Å; D188-Q191 PolarHBondContact O-N 3.49Å; D188-V192 PolarHBondContact O-N 3.31Å; D188-V192 VanDerWaalsContact O-N 3.08Å; D188-L276 HydrophobicContact CB-CD2 4.45Å
189E94.9Very high89.1Confident165 Ų16573.8 Ų73.877%0.77137%0.374SS*.Hα-helixtrans-58.8-29.5-179.6-65.4-177.217100112.5R187 Q191 V192 E193R187-E189 PolarHBondContact O-N 2.8Å; E189-Q191 VanDerWaalsContact C-N 3.34Å; E189-V192 PolarHBondContact O-N 3.21Å; E189-E193 WeakPolarHBondContact O-CB 3.35Å; E189-E193 PolarHBondContact O-N 2.87Å
190T95.8Very high90.6Very high85 Ų8572 Ų7252%0.52136%0.359SS..Hα-helixtrans-69.2-35.1177.969.10000111.8D188 A194D188-T190 VanDerWaalsContact CG-OG1 3.24Å; D188-T190 PolarHBondContact O-N 2.74Å; D188-T190 WeakPolarHBondContact OD1-CB 3.4Å; D188-T190 PolarHBondContact OD1-N 2.92Å; D188-T190 PolarHBondContact OD1-OG1 2.83Å; D188-T190 PolarHBondContact OD2-OG1 3.23Å; T190-A194 WeakPolarHBondContact O-CB 3.44Å; T190-A194 PolarHBondContact O-N 3.47Å
191Q95.1Very high91.8Very high67 Ų6768.8 Ų68.831%0.31334%0.342SS..Hα-helixtrans-75.1-35.6176.7-63-67.1-20.100111.1D188 E189 A194 Y195 H274D188-Q191 HydrophobicContact CB-CB 4.16Å; D188-Q191 HydrophobicContact CB-CG 3.89Å; D188-Q191 PolarHBondContact O-N 3.49Å; E189-Q191 VanDerWaalsContact C-N 3.34Å; Q191-A194 PolarHBondContact O-N 2.84Å; Q191-Y195 WeakPolarHBondContact O-CB 3.42Å; Q191-Y195 PolarHBondContact O-N 3.43Å; Q191-H274 HydrophobicContact CB-CB 4.23Å; Q191-H274 WeakPolarHBondContact CB-O 3.47Å; Q191-H274 HydrophobicContact CG-CB 4.1Å; Q191-H274 VanDerWaalsContact CG-O 3.3Å; Q191-H274 WeakPolarHBondContact CG-O 3.31Å
192V94.1Very high92.7Very high24 Ų2467 Ų6715%0.14533%0.332CS..Hα-helixtrans-62.8-47.1171.6175.90000110.7D188 E189 A194 Y195 D196D188-V192 PolarHBondContact O-N 3.31Å; D188-V192 VanDerWaalsContact O-N 3.08Å; E189-V192 PolarHBondContact O-N 3.21Å; V192-A194 PolarHBondContact O-N 2.84Å; V192-Y195 WeakPolarHBondContact O-CB 3.38Å; V192-Y195 PolarHBondContact O-N 3.34Å; V192-D196 PolarHBondContact O-N 3.26Å
193E94.9Very high93.2Very high124 Ų12470.5 Ų70.558%0.57935%0.346SS*.Hα-helixtrans-63.2-40.9176.8-178.8174.7-162.500112E189 Y195 D196 N197E189-E193 WeakPolarHBondContact O-CB 3.35Å; E189-E193 PolarHBondContact O-N 2.87Å; E193-Y195 VanDerWaalsContact C-N 3.34Å; E193-Y195 PolarHBondContact O-N 3.21Å; E193-D196 PolarHBondContact O-N 3.02Å; E193-N197 VanDerWaalsContact CG-ND2 3.26Å; E193-N197 WeakPolarHBondContact CG-ND2 3.24Å; E193-N197 WeakPolarHBondContact O-CB 3.17Å; E193-N197 PolarHBondContact O-N 3.45Å; E193-N197 PolarHBondContact O-ND2 2.86Å; E193-N197 VanDerWaalsContact O-ND2 3.09Å
194A94.4Very high93.5Very high55 Ų5566.8 Ų66.846%0.45534%0.338SS..Hα-helixtrans-61.5-42.5174.600000111.7T190 Q191 V192 D198T190-A194 WeakPolarHBondContact O-CB 3.44Å; T190-A194 PolarHBondContact O-N 3.47Å; Q191-A194 PolarHBondContact O-N 2.84Å; V192-A194 PolarHBondContact O-N 2.84Å; A194-D198 WeakPolarHBondContact O-CB 3.22Å; A194-D198 PolarHBondContact O-N 2.96Å
195Y93.3Very high93.5Very high39 Ų3969.4 Ų69.415%0.15335%0.348CS..Hα-helixtrans-61.6-47.7175.6177.9-87.5000111.9Q191 V192 E193 N197 D198 N201 H203Q191-Y195 WeakPolarHBondContact O-CB 3.42Å; Q191-Y195 PolarHBondContact O-N 3.43Å; V192-Y195 WeakPolarHBondContact O-CB 3.38Å; V192-Y195 PolarHBondContact O-N 3.34Å; E193-Y195 VanDerWaalsContact C-N 3.34Å; E193-Y195 PolarHBondContact O-N 3.21Å; Y195-N197 VanDerWaalsContact C-N 3.32Å; Y195-N197 PolarHBondContact O-N 3.38Å; Y195-D198 PolarHBondContact O-N 3.17Å; Y195-N201 WeakPolarHBondContact CD2-ND2 3.36Å; Y195-N201 WeakPolarHBondContact CE2-ND2 3.48Å; Y195-N201 PolarHBondContact O-ND2 3.45Å; Y195-H203 PolarHBondContact O-CE1 2.96Å; Y195-H203 VanDerWaalsContact O-CE1 3.22Å
196D93.4Very high93.4Very high72 Ų7270 Ų7039%0.38535%0.35SS..Hα-helixtrans-67.4-31.5-176.6-74.6-19.9000112.6S182 V192 E193 H203S182-D196 WeakPolarHBondContact CB-OD1 3.37Å; S182-D196 VanDerWaalsContact OG-CG 3.31Å; S182-D196 PolarHBondContact OG-OD1 2.91Å; S182-D196 PolarHBondContact OG-OD2 2.92Å; V192-D196 PolarHBondContact O-N 3.26Å; E193-D196 PolarHBondContact O-N 3.02Å; D196-H203 PolarHBondContact O-CE1 2.77Å; D196-H203 PolarHBondContact O-NE2 3.15Å
197N95.6Very high93.1Very high112 Ų11272.6 Ų72.660%0.59936%0.359SS*.Hα-helixtrans-89.1-8.3179.3-71.2-41.2000114.3E193 Y195 E199E193-N197 VanDerWaalsContact CG-ND2 3.26Å; E193-N197 WeakPolarHBondContact CG-ND2 3.24Å; E193-N197 WeakPolarHBondContact O-CB 3.17Å; E193-N197 PolarHBondContact O-N 3.45Å; E193-N197 PolarHBondContact O-ND2 2.86Å; E193-N197 VanDerWaalsContact O-ND2 3.09Å; Y195-N197 VanDerWaalsContact C-N 3.32Å; Y195-N197 PolarHBondContact O-N 3.38Å; N197-E199 PolarHBondContact O-N 3.44Å
198D96.6Very high92.5Very high41 Ų4169.3 Ų69.322%0.21935%0.347CS..  trans-75112179.1-169.7-22.5000110.8H55 A194 Y195 L200 N201 H203H55-D198 IonicContact CD2-OD2 2.93Å; H55-D198 IonicContact CE1-OD2 2.75Å; H55-D198 IonicContact NE2-OD1 3.74Å; H55-D198 PolarHBondContact NE2-OD1 3.44Å; H55-D198 IonicContact NE2-OD2 3.91Å; H55-D198 PolarHBondContact NE2-OD2 3.46Å; A194-D198 WeakPolarHBondContact O-CB 3.22Å; A194-D198 PolarHBondContact O-N 2.96Å; Y195-D198 PolarHBondContact O-N 3.17Å; D198-L200 PolarHBondContact O-N 3.42Å; D198-L200 VanDerWaalsContact OD1-CB 3.31Å; D198-L200 WeakPolarHBondContact OD1-CB 3.29Å; D198-L200 PolarHBondContact OD1-N 3.4Å; D198-N201 HydrophobicContact CB-CB 4.3Å; D198-N201 WeakPolarHBondContact O-CB 3.36Å; D198-N201 PolarHBondContact O-N 3.43Å; D198-N201 VanDerWaalsContact O-N 3.14Å; D198-H203 PolarHBondContact O-NE2 3.21Å; D198-H203 VanDerWaalsContact O-NE2 3.07Å
199E95.9Very high92Very high185 Ų18569.4 Ų69.486%0.86435%0.35SS*.THydrogen-bonded Turntrans-68.9-15.5-179.9-61.6-173.3162.600113.8N197N197-E199 PolarHBondContact O-N 3.44Å
200L97.4Very high91.8Very high38 Ų3861.5 Ų61.520%0.19931%0.313CS..THydrogen-bonded Turntrans-84.4-16.7174.7-61.4-178.7000112.2Q13 H55 Q83 D198Q13-L200 VanDerWaalsContact CD-CD2 3.46Å; Q13-L200 HydrophobicContact CG-CD2 3.69Å; Q13-L200 VanDerWaalsContact NE2-CD2 3.27Å; H55-L200 VanDerWaalsContact CD2-CB 3.41Å; H55-L200 WeakPolarHBondContact CD2-CB 3.17Å; H55-L200 WeakPolarHBondContact NE2-CB 3.47Å; Q83-L200 HydrophobicContact CG-CD1 4.06Å; Q83-L200 HydrophobicContact CG-CD2 3.74Å; D198-L200 PolarHBondContact O-N 3.42Å; D198-L200 VanDerWaalsContact OD1-CB 3.31Å; D198-L200 WeakPolarHBondContact OD1-CB 3.29Å; D198-L200 PolarHBondContact OD1-N 3.4Å
201N96Very high91.4Very high11 Ų1157.5 Ų57.56%0.05929%0.288CS..SBendtrans-74147.7172.6-72-13.3000111.2G53 E54 H55 Y195 D198 H203G53-N201 CarbonylContact O-C 3.51Å; G53-N201 VanDerWaalsContact O-CA 3.29Å; G53-N201 WeakPolarHBondContact O-CA 3.37Å; E54-N201 WeakPolarHBondContact CA-OD1 3.43Å; H55-N201 PolarHBondContact CD2-OD1 3.4Å; Y195-N201 WeakPolarHBondContact CD2-ND2 3.36Å; Y195-N201 WeakPolarHBondContact CE2-ND2 3.48Å; Y195-N201 PolarHBondContact O-ND2 3.45Å; D198-N201 HydrophobicContact CB-CB 4.3Å; D198-N201 WeakPolarHBondContact O-CB 3.36Å; D198-N201 PolarHBondContact O-N 3.43Å; D198-N201 VanDerWaalsContact O-N 3.14Å; N201-H203 PolarHBondContact O-N 3.2Å
202Y93.8Very high91Very high60 Ų6057.3 Ų57.324%0.23529%0.289CS..  trans-90.1104.5174.2-178-100.3000110.8G53 R88 M89 G204 R205G53-Y202 PolarHBondContact O-N 2.75Å; R88-Y202 HydrophobicContact CB-CD2 3.76Å; R88-Y202 HydrophobicContact CB-CE2 3.75Å; R88-Y202 HydrophobicContact CG-CD2 4.43Å; M89-Y202 HydrophobicContact CB-CD1 3.82Å; M89-Y202 HydrophobicContact CB-CD2 4.49Å; M89-Y202 HydrophobicContact CB-CE1 3.84Å; M89-Y202 HydrophobicContact CB-CG 4.12Å; M89-Y202 HydrophobicContact CE-CD1 4.43Å; M89-Y202 HydrophobicContact CG-CD1 3.41Å; M89-Y202 VanDerWaalsContact CG-CD1 3.41Å; M89-Y202 HydrophobicContact CG-CD2 4.27Å; M89-Y202 HydrophobicContact CG-CE1 3.98Å; M89-Y202 HydrophobicContact CG-CG 3.54Å; Y202-G204 VanDerWaalsContact C-N 3.31Å; Y202-G204 WeakPolarHBondContact CE1-O 3.34Å; Y202-G204 VanDerWaalsContact CZ-CA 3.41Å; Y202-R205 PolarHBondContact OH-O 2.89Å
203H90.5Very high91Very high93 Ų9357.9 Ų57.943%0.43129%0.29SS..  trans-89.15.2177.1-60.8-61.1000114.1Y195 D196 D198 N201Y195-H203 PolarHBondContact O-CE1 2.96Å; Y195-H203 VanDerWaalsContact O-CE1 3.22Å; D196-H203 PolarHBondContact O-CE1 2.77Å; D196-H203 PolarHBondContact O-NE2 3.15Å; D198-H203 PolarHBondContact O-NE2 3.21Å; D198-H203 VanDerWaalsContact O-NE2 3.07Å; N201-H203 PolarHBondContact O-N 3.2Å
204G87Confident90.9Very high30 Ų3052.4 Ų52.431%0.30926%0.264SS..SBendtrans-79.2178.7-179.900000113.3Y202Y202-G204 VanDerWaalsContact C-N 3.31Å; Y202-G204 WeakPolarHBondContact CE1-O 3.34Å; Y202-G204 VanDerWaalsContact CZ-CA 3.41Å
205R84Confident90.7Very high137 Ų13751.4 Ų51.452%0.51725%0.251SS..PPolyproline II helixtrans-82.2140.9-178.9-67.1-17973.9142.75.8111.2T176 L177 Y202 R207T176-R205 VanDerWaalsContact CB-CB 3.5Å; T176-R205 HydrophobicContact CG2-CB 4.15Å; L177-R205 VanDerWaalsContact O-CB 3.29Å; L177-R205 WeakPolarHBondContact O-CB 3.48Å; L177-R205 PolarHBondContact O-NE 3.46Å; L177-R205 PolarHBondContact O-NH2 3.27Å; Y202-R205 PolarHBondContact OH-O 2.89Å; R205-R207 PolarHBondContact O-N 3.22Å
206L83.5Confident90.7Very high32 Ų3251.6 Ų51.617%0.16826%0.26CS..PPolyproline II helixtrans-63.4119.7-179.7-171.774.4000110.9M89 F160 T176 L177 G178 F210M89-L206 HydrophobicContact CE-CD1 3.8Å; F160-L206 HydrophobicContact CE2-CD2 4.21Å; T176-L206 CarbonylContact C-O 3.53Å; T176-L206 WeakPolarHBondContact CA-O 3.33Å; L177-L206 HydrophobicContact CB-CB 4.43Å; L177-L206 PolarHBondContact N-O 3.06Å; G178-L206 PolarHBondContact O-N 2.79Å; L206-F210 HydrophobicContact CD1-CD1 3.58Å; L206-F210 HydrophobicContact CD1-CE1 4.17Å
207R86.7Confident90.8Very high59 Ų5948.2 Ų48.222%0.22324%0.243CC..BIsolated β-bridgetrans-70143.2175.5-69.2176.2174.4-151.47.7111.2E87 T176 R205 S209 F210 G211E87-R207 IonicContact OE1-CZ 3.76Å; E87-R207 IonicContact OE1-NH1 3.38Å; E87-R207 PolarHBondContact OE1-NH1 2.95Å; E87-R207 IonicContact OE1-NH2 3.76Å; E87-R207 PolarHBondContact OE1-NH2 3.28Å; E87-R207 IonicContact OE2-NH1 2.87Å; E87-R207 PolarHBondContact OE2-NH1 3.41Å; E87-R207 VanDerWaalsContact OE2-NH1 3.11Å; T176-R207 HydrophobicContact CG2-CG 4.15Å; R205-R207 PolarHBondContact O-N 3.22Å; R207-S209 VanDerWaalsContact C-N 3.33Å; R207-S209 PolarHBondContact O-N 3.11Å; R207-F210 HydrophobicContact CB-CB 4.3Å; R207-F210 PolarHBondContact O-N 3.07Å; R207-G211 PolarHBondContact O-N 2.71Å
208V83.3Confident90.8Very high1 Ų143.3 Ų43.31%0.00622%0.217CC..Hα-helixtrans-61.4-42.8177.8174.50000111.6F163 V164 L167 L175 L177 F210 G211 I212F163-V208 HydrophobicContact CD1-CG2 3.81Å; F163-V208 HydrophobicContact CE1-CG2 3.5Å; F163-V208 VanDerWaalsContact CE1-CG2 3.5Å; V164-V208 HydrophobicContact CG2-CG1 3.76Å; L167-V208 HydrophobicContact CD2-CB 3.86Å; L167-V208 HydrophobicContact CD2-CG1 3.47Å; L167-V208 VanDerWaalsContact CD2-CG1 3.47Å; L167-V208 HydrophobicContact CD2-CG2 3.96Å; L175-V208 HydrophobicContact CB-CG2 4.2Å; L175-V208 WeakPolarHBondContact O-CG2 3.48Å; L175-V208 PolarHBondContact O-N 3.25Å; L177-V208 HydrophobicContact CD1-CG2 3.89Å; L177-V208 HydrophobicContact CG-CG2 4.05Å; V208-F210 PolarHBondContact O-N 3.41Å; V208-G211 PolarHBondContact O-N 2.71Å; V208-I212 HydrophobicContact CG1-CD1 3.92Å; V208-I212 HydrophobicContact CG1-CG1 4.29Å; V208-I212 WeakPolarHBondContact O-CG1 3.19Å; V208-I212 PolarHBondContact O-N 3.41Å
209S85.6Confident90.7Very high27 Ų2746 Ų4619%0.18923%0.229CC..Hα-helixtrans-53-43.417655.10000111.9N90 R207 I212 Q213N90-S209 PolarHBondContact OD1-OG 2.85Å; R207-S209 VanDerWaalsContact C-N 3.33Å; R207-S209 PolarHBondContact O-N 3.11Å; S209-I212 PolarHBondContact O-N 3.29Å; S209-Q213 WeakPolarHBondContact O-CG 3.35Å; S209-Q213 PolarHBondContact O-N 2.82Å
210F90.1Very high90.8Very high0 Ų040.1 Ų40.10%020%0.199CC..Hα-helixtrans-71.3-43.5179.6-171.4-111.3000112.1A52 M89 I91 Y97 M124 L206 R207 V208 I212 Q213 L214A52-F210 HydrophobicContact CB-CE1 4.16Å; A52-F210 HydrophobicContact CB-CZ 4.45Å; M89-F210 HydrophobicContact CE-CD1 3.93Å; M89-F210 HydrophobicContact CE-CE1 3.52Å; M89-F210 HydrophobicContact CE-CZ 4.4Å; M89-F210 WeakPolarHBondContact O-CB 3.45Å; M89-F210 VanDerWaalsContact O-CG 3.24Å; M89-F210 WeakPolarHBondContact O-CG 3.48Å; M89-F210 HydrophobicContact SD-CD1 4.31Å; M89-F210 HydrophobicContact SD-CE1 3.66Å; M89-F210 HydrophobicContact SD-CZ 3.96Å; I91-F210 HydrophobicContact CG2-CD2 4.01Å; I91-F210 HydrophobicContact CG2-CE2 4.04Å; Y97-F210 HydrophobicContact CE2-CE2 4.11Å; Y97-F210 WeakPolarHBondContact OH-CE2 3.38Å; M124-F210 HydrophobicContact SD-CE1 4.44Å; M124-F210 HydrophobicContact SD-CE2 4.49Å; M124-F210 HydrophobicContact SD-CZ 3.63Å; L206-F210 HydrophobicContact CD1-CD1 3.58Å; L206-F210 HydrophobicContact CD1-CE1 4.17Å; R207-F210 HydrophobicContact CB-CB 4.3Å; R207-F210 PolarHBondContact O-N 3.07Å; V208-F210 PolarHBondContact O-N 3.41Å; F210-I212 VanDerWaalsContact C-N 3.27Å; F210-I212 PolarHBondContact O-N 2.87Å; F210-Q213 WeakPolarHBondContact O-CA 3.39Å; F210-Q213 WeakPolarHBondContact O-CB 2.92Å; F210-Q213 PolarHBondContact O-N 3.23Å; F210-L214 HydrophobicContact CD1-CD1 4.18Å; F210-L214 HydrophobicContact CD1-CG 4.31Å; F210-L214 HydrophobicContact CE1-CD1 3.96Å; F210-L214 HydrophobicContact CE1-CD2 3.99Å; F210-L214 HydrophobicContact CE1-CG 4.09Å; F210-L214 HydrophobicContact CZ-CD2 4.02Å; F210-L214 PolarHBondContact O-N 3Å
211G87.9Confident90.8Very high0 Ų038.3 Ų38.30%019%0.189CC..Hα-helixtrans-63.5-30.4175.700000113.7F160 R207 V208 Q213 L214 M215F160-G211 VanDerWaalsContact CZ-CA 3.41Å; R207-G211 PolarHBondContact O-N 2.71Å; V208-G211 PolarHBondContact O-N 2.71Å; G211-Q213 VanDerWaalsContact C-N 3.3Å; G211-Q213 PolarHBondContact O-N 3.07Å; G211-L214 PolarHBondContact O-N 3.34Å; G211-M215 PolarHBondContact O-N 2.87Å
212I87.5Confident90.8Very high64 Ų6441.8 Ų41.833%0.32821%0.205SC..Hα-helixtrans-61-41.2169.8-71.2167.8000110.5V164 V208 S209 F210 M215 A216V164-I212 HydrophobicContact CG1-CD1 4.19Å; V164-I212 HydrophobicContact CG1-CG1 4.21Å; V164-I212 HydrophobicContact CG2-CG1 4.34Å; V208-I212 HydrophobicContact CG1-CD1 3.92Å; V208-I212 HydrophobicContact CG1-CG1 4.29Å; V208-I212 WeakPolarHBondContact O-CG1 3.19Å; V208-I212 PolarHBondContact O-N 3.41Å; S209-I212 PolarHBondContact O-N 3.29Å; F210-I212 VanDerWaalsContact C-N 3.27Å; F210-I212 PolarHBondContact O-N 2.87Å; I212-M215 PolarHBondContact O-N 3.19Å; I212-A216 WeakPolarHBondContact O-CB 3.34Å; I212-A216 PolarHBondContact O-N 2.74Å
213Q94.3Very high91Very high35 Ų3546.7 Ų46.716%0.16422%0.223CC..Hα-helixtrans-66-39.4176.1-62.7-59.9-34.800112.2I91 R92 F94 S209 F210 G211 A216 A217I91-Q213 HydrophobicContact CG2-CB 4.12Å; I91-Q213 HydrophobicContact CG2-CG 3.92Å; R92-Q213 PolarHBondContact O-NE2 2.88Å; R92-Q213 VanDerWaalsContact O-NE2 3.11Å; F94-Q213 HydrophobicContact CB-CB 4.36Å; F94-Q213 HydrophobicContact CD2-CB 4.45Å; S209-Q213 WeakPolarHBondContact O-CG 3.35Å; S209-Q213 PolarHBondContact O-N 2.82Å; F210-Q213 WeakPolarHBondContact O-CA 3.39Å; F210-Q213 WeakPolarHBondContact O-CB 2.92Å; F210-Q213 PolarHBondContact O-N 3.23Å; G211-Q213 VanDerWaalsContact C-N 3.3Å; G211-Q213 PolarHBondContact O-N 3.07Å; Q213-A216 PolarHBondContact O-N 3.1Å; Q213-A217 WeakPolarHBondContact O-CB 3.2Å; Q213-A217 PolarHBondContact O-N 2.7Å
214L93.1Very high91.4Very high10 Ų1045 Ų455%0.05222%0.215CC..Hα-helixtrans-61.6-43.5174.3-61.3-178.5000111.9F94 M124 M149 M152 F210 G211 A217 A218F94-L214 HydrophobicContact CE2-CD2 3.97Å; M124-L214 HydrophobicContact CG-CD2 3.95Å; M124-L214 HydrophobicContact SD-CD2 3.92Å; M149-L214 HydrophobicContact CE-CB 4.01Å; M149-L214 HydrophobicContact CE-CD2 3.9Å; M149-L214 WeakPolarHBondContact CE-O 3.49Å; M149-L214 HydrophobicContact SD-CB 3.94Å; M149-L214 HydrophobicContact SD-CD1 4.4Å; M149-L214 HydrophobicContact SD-CD2 3.96Å; M149-L214 HydrophobicContact SD-CG 4.31Å; M152-L214 HydrophobicContact SD-CB 4.23Å; F210-L214 HydrophobicContact CD1-CD1 4.18Å; F210-L214 HydrophobicContact CD1-CG 4.31Å; F210-L214 HydrophobicContact CE1-CD1 3.96Å; F210-L214 HydrophobicContact CE1-CD2 3.99Å; F210-L214 HydrophobicContact CE1-CG 4.09Å; F210-L214 HydrophobicContact CZ-CD2 4.02Å; F210-L214 PolarHBondContact O-N 3Å; G211-L214 PolarHBondContact O-N 3.34Å; L214-A217 PolarHBondContact O-N 2.87Å; L214-A218 PolarHBondContact O-N 3.23Å
215M90.3Very high91.9Very high34 Ų3443.6 Ų43.617%0.16720%0.201CC..Hα-helixtrans-63.5-45.4175.5-75.7-174.551.900112.2M152 F160 K161 G211 I212 A217 A218 E219M152-M215 HydrophobicContact SD-CG 3.91Å; F160-M215 HydrophobicContact CD1-SD 3.51Å; F160-M215 VanDerWaalsContact CD1-SD 3.51Å; F160-M215 HydrophobicContact CE1-CG 4.19Å; F160-M215 HydrophobicContact CE1-SD 3.37Å; F160-M215 WeakPolarHBondContact CE1-SD 3.44Å; K161-M215 HydrophobicContact CD-CE 4.27Å; K161-M215 VanDerWaalsContact CE-CE 3.46Å; K161-M215 HydrophobicContact CG-CE 3.84Å; K161-M215 HydrophobicContact CG-SD 4.12Å; G211-M215 PolarHBondContact O-N 2.87Å; I212-M215 PolarHBondContact O-N 3.19Å; M215-A217 VanDerWaalsContact C-N 3.25Å; M215-A217 PolarHBondContact O-N 2.82Å; M215-A218 PolarHBondContact O-N 2.99Å; M215-E219 WeakPolarHBondContact O-CG 3.36Å; M215-E219 PolarHBondContact O-N 3.11Å
216A91.8Very high92.6Very high42 Ų4241.3 Ų41.335%0.34720%0.203SC..Hα-helixtrans-60.8-36.8177.700000111.9I212 Q213 R220I212-A216 WeakPolarHBondContact O-CB 3.34Å; I212-A216 PolarHBondContact O-N 2.74Å; Q213-A216 PolarHBondContact O-N 3.1Å; A216-R220 WeakPolarHBondContact O-CB 3.2Å; A216-R220 PolarHBondContact O-N 3.28Å
217A96.9Very high93.3Very high2 Ų242.6 Ų42.62%0.01722%0.215CC..Hα-helixtrans-65.1-47.7174.200000112F94 L131 M149 Q213 L214 M215 E219 R220 I221F94-A217 HydrophobicContact CB-CB 4.39Å; F94-A217 HydrophobicContact CD1-CB 3.51Å; F94-A217 HydrophobicContact CD2-CB 3.91Å; F94-A217 HydrophobicContact CE1-CB 3.61Å; F94-A217 HydrophobicContact CE2-CB 4Å; F94-A217 HydrophobicContact CG-CB 3.67Å; F94-A217 HydrophobicContact CZ-CB 3.85Å; L131-A217 HydrophobicContact CD1-CB 4.29Å; M149-A217 HydrophobicContact CE-CB 4.2Å; Q213-A217 WeakPolarHBondContact O-CB 3.2Å; Q213-A217 PolarHBondContact O-N 2.7Å; L214-A217 PolarHBondContact O-N 2.87Å; M215-A217 VanDerWaalsContact C-N 3.25Å; M215-A217 PolarHBondContact O-N 2.82Å; A217-E219 PolarHBondContact O-N 2.74Å; A217-R220 WeakPolarHBondContact O-CB 3.08Å; A217-R220 PolarHBondContact O-N 3.34Å; A217-I221 WeakPolarHBondContact O-CG1 3.45Å; A217-I221 PolarHBondContact O-N 2.75Å
218A94.9Very high93.8Very high8 Ų839.8 Ų39.87%0.06621%0.205CC..Hα-helixtrans-59.5-46.5176.300000111.7L214 M215 R220 I221 E222L214-A218 PolarHBondContact O-N 3.23Å; M215-A218 PolarHBondContact O-N 2.99Å; A218-R220 VanDerWaalsContact C-N 3.29Å; A218-R220 PolarHBondContact O-N 3.48Å; A218-I221 PolarHBondContact O-N 3.35Å; A218-E222 WeakPolarHBondContact O-CG 3.43Å; A218-E222 PolarHBondContact O-N 2.68Å
219E94.2Very high94.5Very high99 Ų9943.1 Ų43.146%0.46323%0.228SC..Hα-helixtrans-61.6-36.7175.7-72.3177.7-174.900112.5M215 A217 R223M215-E219 WeakPolarHBondContact O-CG 3.36Å; M215-E219 PolarHBondContact O-N 3.11Å; A217-E219 PolarHBondContact O-N 2.74Å; E219-R223 WeakPolarHBondContact O-CG 3.43Å; E219-R223 PolarHBondContact O-N 3.04Å; E219-R223 PolarHBondContact O-NH1 3.29Å; E219-R223 VanDerWaalsContact O-NH1 3.12Å
220R97.6Very high95.1Very high61 Ų6142.1 Ų42.123%0.2322%0.22CC..Hα-helixtrans-66.3-46173.9-176.9-179.7171.5-171.9-5.3111.1L131 E135 A216 A217 A218 E222 R223 E224L131-R220 HydrophobicContact CD2-CB 4.27Å; L131-R220 HydrophobicContact CD2-CG 3.7Å; E135-R220 IonicContact OE2-NH2 2.87Å; A216-R220 WeakPolarHBondContact O-CB 3.2Å; A216-R220 PolarHBondContact O-N 3.28Å; A217-R220 WeakPolarHBondContact O-CB 3.08Å; A217-R220 PolarHBondContact O-N 3.34Å; A218-R220 VanDerWaalsContact C-N 3.29Å; A218-R220 PolarHBondContact O-N 3.48Å; R220-E222 VanDerWaalsContact C-N 3.29Å; R220-E222 PolarHBondContact O-N 2.86Å; R220-R223 WeakPolarHBondContact O-CB 3.2Å; R220-R223 PolarHBondContact O-N 3.26Å; R220-R223 VanDerWaalsContact O-N 3.09Å; R220-E224 HydrophobicContact CG-CG 4.35Å; R220-E224 WeakPolarHBondContact O-CG 3.29Å; R220-E224 PolarHBondContact O-N 2.96Å
221I98.3Very high95.5Very high0 Ų043.6 Ų43.60%023%0.23CC..Hα-helixtrans-56.3-46.6176.9-70.6165.3000110.2A127 I130 L131 V150 A217 A218 R223 E224 I225A127-I221 HydrophobicContact CB-CD1 3.51Å; I130-I221 HydrophobicContact CB-CD1 4.48Å; I130-I221 HydrophobicContact CB-CG1 4.46Å; I130-I221 HydrophobicContact CD1-CD1 4.29Å; I130-I221 HydrophobicContact CD1-CG2 4.36Å; I130-I221 HydrophobicContact CG2-CG1 4.02Å; I130-I221 HydrophobicContact CG2-CG2 4.03Å; L131-I221 HydrophobicContact CD1-CG1 4.25Å; L131-I221 HydrophobicContact CD2-CG1 3.68Å; L131-I221 HydrophobicContact CG-CD1 4.37Å; L131-I221 HydrophobicContact CG-CG1 3.77Å; V150-I221 HydrophobicContact CB-CG2 4.49Å; V150-I221 HydrophobicContact CG1-CG2 3.93Å; V150-I221 HydrophobicContact CG2-CG2 4.4Å; A217-I221 WeakPolarHBondContact O-CG1 3.45Å; A217-I221 PolarHBondContact O-N 2.75Å; A218-I221 PolarHBondContact O-N 3.35Å; I221-R223 PolarHBondContact O-N 3Å; I221-E224 CarbonylContact O-C 3.55Å; I221-E224 PolarHBondContact O-N 2.8Å; I221-I225 HydrophobicContact CG2-CD1 4.36Å; I221-I225 HydrophobicContact CG2-CG1 4.24Å; I221-I225 WeakPolarHBondContact O-CG1 3.37Å; I221-I225 PolarHBondContact O-N 2.61Å
222E96.3Very high96.1Very high83 Ų8343.6 Ų43.639%0.38823%0.23SC..Hα-helixtrans-55.4-37.9178-72-169.8-177.100113.1Q151 A218 R220 M250Q151-E222 WeakPolarHBondContact CG-OE1 3.3Å; Q151-E222 PolarHBondContact NE2-OE1 3.27Å; A218-E222 WeakPolarHBondContact O-CG 3.43Å; A218-E222 PolarHBondContact O-N 2.68Å; R220-E222 VanDerWaalsContact C-N 3.29Å; R220-E222 PolarHBondContact O-N 2.86Å; E222-M250 HydrophobicContact CG-CE 3.81Å
223R97.7Very high96.6Very high163 Ų16340.5 Ų40.562%0.61521%0.214SC*.Hα-helixtrans-72.5-31.4175.6-67.2-172.8-61.3-89.65.7113.1E219 R220 I221 P226E219-R223 WeakPolarHBondContact O-CG 3.43Å; E219-R223 PolarHBondContact O-N 3.04Å; E219-R223 PolarHBondContact O-NH1 3.29Å; E219-R223 VanDerWaalsContact O-NH1 3.12Å; R220-R223 WeakPolarHBondContact O-CB 3.2Å; R220-R223 PolarHBondContact O-N 3.26Å; R220-R223 VanDerWaalsContact O-N 3.09Å; I221-R223 PolarHBondContact O-N 3Å; R223-P226 WeakPolarHBondContact O-CD 3.35Å
224E98.3Very high96.8Very high57 Ų5738.9 Ų38.927%0.26621%0.206SC..Hα-helixtrans-82.1-24.2179.6-67-63.7167.200113.1L131 C134 R220 I221 P226 S227 I228L131-E224 HydrophobicContact CD2-CG 4.32Å; C134-E224 HydrophobicContact CB-CB 4.37Å; C134-E224 HydrophobicContact CB-CG 4.26Å; R220-E224 HydrophobicContact CG-CG 4.35Å; R220-E224 WeakPolarHBondContact O-CG 3.29Å; R220-E224 PolarHBondContact O-N 2.96Å; I221-E224 CarbonylContact O-C 3.55Å; I221-E224 PolarHBondContact O-N 2.8Å; E224-P226 VanDerWaalsContact C-CD 3.41Å; E224-P226 VanDerWaalsContact C-N 3.3Å; E224-P226 VanDerWaalsContact O-N 3.07Å; E224-S227 WeakPolarHBondContact O-CA 3.3Å; E224-S227 WeakPolarHBondContact O-CB 3.34Å; E224-S227 PolarHBondContact O-N 2.84Å; E224-S227 PolarHBondContact O-OG 3.25Å; E224-S227 PolarHBondContact OE2-OG 2.75Å; E224-S227 VanDerWaalsContact OE2-OG 3.11Å; E224-I228 PolarHBondContact O-N 2.94Å
225I98.4Very high97.1Very high2 Ų238.4 Ų38.41%0.0120%0.204CC..G310 helixtrans-46.3-45.2-177.3-76166.7000113.8V150 I221 S227 I228 M250 M251 K254 A255V150-I225 HydrophobicContact CG1-CD1 4.07Å; I221-I225 HydrophobicContact CG2-CD1 4.36Å; I221-I225 HydrophobicContact CG2-CG1 4.24Å; I221-I225 WeakPolarHBondContact O-CG1 3.37Å; I221-I225 PolarHBondContact O-N 2.61Å; I225-S227 PolarHBondContact O-N 3.33Å; I225-S227 VanDerWaalsContact O-N 3.15Å; I225-I228 HydrophobicContact CG1-CD1 4.26Å; I225-I228 WeakPolarHBondContact O-CB 3.48Å; I225-I228 PolarHBondContact O-N 2.65Å; I225-I228 VanDerWaalsContact O-N 3.13Å; I225-M250 HydrophobicContact CD1-CE 3.77Å; I225-M250 HydrophobicContact CD1-CG 4.42Å; I225-M251 HydrophobicContact CD1-CB 4.08Å; I225-M251 HydrophobicContact CG1-CB 4.33Å; I225-M251 HydrophobicContact CG1-CG 4.26Å; I225-K254 HydrophobicContact CG2-CB 3.53Å; I225-A255 HydrophobicContact CG2-CB 4.46Å; I225-A255 WeakPolarHBondContact O-CA 3.24Å
226P98.1Very high97.5Very high88 Ų8836.8 Ų36.857%0.57120%0.196SC*.G310 helixtrans-63.5-15.6177.8-23.135.5000115.4R223 E224 P256R223-P226 WeakPolarHBondContact O-CD 3.35Å; E224-P226 VanDerWaalsContact C-CD 3.41Å; E224-P226 VanDerWaalsContact C-N 3.3Å; E224-P226 VanDerWaalsContact O-N 3.07Å; P226-P256 WeakPolarHBondContact O-CD 3.46Å; P226-P256 WeakPolarHBondContact O-CG 3.35Å
227S97.7Very high97.8Very high60 Ų6034.9 Ų34.942%0.4218%0.18SC..G310 helixtrans-94.4-10.117779.50000113.2E224 I225 S229E224-S227 WeakPolarHBondContact O-CA 3.3Å; E224-S227 WeakPolarHBondContact O-CB 3.34Å; E224-S227 PolarHBondContact O-N 2.84Å; E224-S227 PolarHBondContact O-OG 3.25Å; E224-S227 PolarHBondContact OE2-OG 2.75Å; E224-S227 VanDerWaalsContact OE2-OG 3.11Å; I225-S227 PolarHBondContact O-N 3.33Å; I225-S227 VanDerWaalsContact O-N 3.15Å; S227-S229 PolarHBondContact O-N 2.76Å
228I98.6Very high97.8Very high0 Ų038.5 Ų38.50%020%0.199CC..  trans-7396-173.7-64179000111.4I130 E224 I225 W230 F232 M251 A255 P256 S257I130-I228 HydrophobicContact CG2-CD1 3.94Å; E224-I228 PolarHBondContact O-N 2.94Å; I225-I228 HydrophobicContact CG1-CD1 4.26Å; I225-I228 WeakPolarHBondContact O-CB 3.48Å; I225-I228 PolarHBondContact O-N 2.65Å; I225-I228 VanDerWaalsContact O-N 3.13Å; I228-W230 HydrophobicContact CB-CZ2 4.33Å; I228-W230 HydrophobicContact CD1-CH2 4.31Å; I228-W230 HydrophobicContact CD1-CZ2 3.85Å; I228-W230 HydrophobicContact CG1-CZ2 3.91Å; I228-W230 HydrophobicContact CG2-CD2 3.82Å; I228-W230 HydrophobicContact CG2-CE3 4.09Å; I228-W230 HydrophobicContact CG2-CG 4.48Å; I228-W230 HydrophobicContact CG2-CH2 3.86Å; I228-W230 HydrophobicContact CG2-CZ2 3.57Å; I228-W230 HydrophobicContact CG2-CZ3 4.1Å; I228-F232 HydrophobicContact CG2-CD1 4.06Å; I228-F232 HydrophobicContact CG2-CE1 3.91Å; I228-M251 HydrophobicContact CD1-CE 3.87Å; I228-M251 HydrophobicContact CG2-CE 4.31Å; I228-A255 HydrophobicContact CB-CB 3.88Å; I228-A255 HydrophobicContact CG2-CB 3.96Å; I228-P256 WeakPolarHBondContact O-CD 3.47Å; I228-P256 WeakPolarHBondContact O-CG 3.49Å; I228-S257 PolarHBondContact O-N 3.14Å
229S97.7Very high97.8Very high71 Ų7139.4 Ų39.450%0.49721%0.206SC..  trans-105.8-9176.365.90000114.4S227 S257S227-S229 PolarHBondContact O-N 2.76Å; S229-S257 PolarHBondContact O-OG 3.33Å
230W98.4Very high97.8Very high5 Ų535.2 Ų35.22%0.01919%0.187CC..SBendtrans-73.7153-179.339.9-101000112.2I130 A133 V143 I228 F232 M251 S257I130-W230 HydrophobicContact CB-CH2 4.49Å; I130-W230 HydrophobicContact CG1-CH2 4.2Å; I130-W230 HydrophobicContact CG2-CH2 4.44Å; I130-W230 HydrophobicContact CG2-CZ2 4.24Å; A133-W230 HydrophobicContact CB-CD2 3.9Å; A133-W230 VanDerWaalsContact CB-CE2 3.45Å; A133-W230 HydrophobicContact CB-CG 4.25Å; A133-W230 HydrophobicContact CB-CH2 4.38Å; A133-W230 HydrophobicContact CB-CZ2 3.74Å; V143-W230 HydrophobicContact CB-CE3 3.81Å; V143-W230 HydrophobicContact CB-CH2 4.31Å; V143-W230 HydrophobicContact CB-CZ3 3.51Å; V143-W230 HydrophobicContact CG1-CH2 4.36Å; V143-W230 HydrophobicContact CG1-CZ3 3.99Å; V143-W230 HydrophobicContact CG2-CD2 4.15Å; V143-W230 HydrophobicContact CG2-CE3 3.55Å; V143-W230 HydrophobicContact CG2-CH2 4.34Å; V143-W230 HydrophobicContact CG2-CZ3 3.67Å; I228-W230 HydrophobicContact CB-CZ2 4.33Å; I228-W230 HydrophobicContact CD1-CH2 4.31Å; I228-W230 HydrophobicContact CD1-CZ2 3.85Å; I228-W230 HydrophobicContact CG1-CZ2 3.91Å; I228-W230 HydrophobicContact CG2-CD2 3.82Å; I228-W230 HydrophobicContact CG2-CE3 4.09Å; I228-W230 HydrophobicContact CG2-CG 4.48Å; I228-W230 HydrophobicContact CG2-CH2 3.86Å; I228-W230 HydrophobicContact CG2-CZ2 3.57Å; I228-W230 HydrophobicContact CG2-CZ3 4.1Å; W230-F232 HydrophobicContact CE3-CB 3.88Å; W230-F232 HydrophobicContact CE3-CD1 4.02Å; W230-F232 HydrophobicContact CE3-CG 4.4Å; W230-F232 HydrophobicContact CZ3-CB 3.53Å; W230-F232 AromaticContact CZ3-CD1 3.86Å; W230-F232 HydrophobicContact CZ3-CD1 3.86Å; W230-F232 AromaticContact CZ3-CG 3.99Å; W230-F232 HydrophobicContact CZ3-CG 3.99Å; W230-F232 WeakPolarHBondContact O-CD1 3.4Å; W230-M251 HydrophobicContact CH2-CE 3.61Å; W230-M251 HydrophobicContact CZ2-CE 4.47Å; W230-M251 HydrophobicContact CZ3-CE 4.11Å; W230-S257 VanDerWaalsContact O-CB 3.3Å; W230-S257 WeakPolarHBondContact O-CB 3.42Å; W230-S257 PolarHBondContact O-OG 2.9Å
231P98.8Very high97.4Very high31 Ų3136.9 Ų36.920%0.20120%0.196CC..  trans-65.3138.9-179.5-25.637000113.7T141 G142 V143 D259 W290T141-P231 WeakPolarHBondContact O-CG 3.17Å; G142-P231 WeakPolarHBondContact CA-O 3.43Å; V143-P231 PolarHBondContact N-O 3.28Å; P231-D259 CarbonylContact C-O 3.54Å; P231-D259 WeakPolarHBondContact CA-O 3.44Å; P231-D259 HydrophobicContact CB-CB 3.98Å; P231-D259 HydrophobicContact CG-CB 4.24Å; P231-W290 HydrophobicContact CB-CH2 4Å; P231-W290 HydrophobicContact CB-CZ2 4.17Å
232F98.9Very high96.9Very high0 Ų038.9 Ų38.90%021%0.207CC..EExtended strand (participates in β ladder)trans-149.4152177.367.5-99.6000117.6V143 I228 W230 L234 M251 F252 A255 D259 K260 K261V143-F232 HydrophobicContact CB-CB 4.46Å; V143-F232 CarbonylContact O-C 3.59Å; V143-F232 WeakPolarHBondContact O-CA 3.39Å; V143-F232 VanDerWaalsContact O-CB 3.3Å; V143-F232 WeakPolarHBondContact O-CB 3.26Å; I228-F232 HydrophobicContact CG2-CD1 4.06Å; I228-F232 HydrophobicContact CG2-CE1 3.91Å; W230-F232 HydrophobicContact CE3-CB 3.88Å; W230-F232 HydrophobicContact CE3-CD1 4.02Å; W230-F232 HydrophobicContact CE3-CG 4.4Å; W230-F232 HydrophobicContact CZ3-CB 3.53Å; W230-F232 AromaticContact CZ3-CD1 3.86Å; W230-F232 HydrophobicContact CZ3-CD1 3.86Å; W230-F232 AromaticContact CZ3-CG 3.99Å; W230-F232 HydrophobicContact CZ3-CG 3.99Å; W230-F232 WeakPolarHBondContact O-CD1 3.4Å; F232-L234 HydrophobicContact CD2-CD1 3.99Å; F232-L234 HydrophobicContact CD2-CG 3.87Å; F232-L234 HydrophobicContact CE2-CD1 3.5Å; F232-L234 HydrophobicContact CE2-CG 3.93Å; F232-M251 HydrophobicContact CD1-CE 4.3Å; F232-M251 HydrophobicContact CD2-CE 4.4Å; F232-M251 HydrophobicContact CE1-CE 4.3Å; F232-M251 HydrophobicContact CE2-CE 4.4Å; F232-M251 HydrophobicContact CG-CE 4.36Å; F232-M251 HydrophobicContact CZ-CE 4.34Å; F232-F252 HydrophobicContact CE2-CD2 4.22Å; F232-A255 HydrophobicContact CE1-CB 3.88Å; F232-A255 HydrophobicContact CZ-CB 4.03Å; F232-D259 PolarHBondContact N-O 3.06Å; F232-K260 HydrophobicContact CD1-CB 4.1Å; F232-K260 HydrophobicContact CD2-CB 4.01Å; F232-K260 HydrophobicContact CE1-CB 3.66Å; F232-K260 HydrophobicContact CE1-CD 4.21Å; F232-K260 HydrophobicContact CE2-CB 3.56Å; F232-K260 HydrophobicContact CG-CB 4.27Å; F232-K260 HydrophobicContact CZ-CB 3.37Å; F232-K260 HydrophobicContact CZ-CD 3.75Å; F232-K260 HydrophobicContact CZ-CG 4.19Å; F232-K260 WeakPolarHBondContact O-CA 3.34Å; F232-K261 PolarHBondContact O-N 3.16Å
233L98.9Very high96.7Very high0 Ų035.1 Ų35.10%019%0.189CC..EExtended strand (participates in β ladder)trans-113.7125.1167.817663.1000109.5V143 V144 L145 L235 K261 W290V143-L233 PolarHBondContact O-N 3.12Å; V144-L233 HydrophobicContact CG1-CB 4.23Å; V144-L233 HydrophobicContact CG1-CD2 3.93Å; V144-L233 HydrophobicContact CG1-CG 4.3Å; V144-L233 HydrophobicContact CG2-CB 4.27Å; L145-L233 PolarHBondContact N-O 3.25Å; L233-L235 HydrophobicContact CD1-CD2 3.85Å; L233-L235 HydrophobicContact CD1-CG 4.47Å; L233-L235 HydrophobicContact CD2-CD1 4.24Å; L233-L235 HydrophobicContact CD2-CD2 4.08Å; L233-L235 HydrophobicContact CD2-CG 4.16Å; L233-L235 HydrophobicContact CG-CD2 3.97Å; L233-L235 HydrophobicContact CG-CG 4.06Å; L233-K261 HydrophobicContact CD1-CB 3.89Å; L233-K261 HydrophobicContact CD1-CD 3.88Å; L233-K261 HydrophobicContact CD1-CG 3.93Å; L233-W290 HydrophobicContact CB-CD2 3.76Å; L233-W290 HydrophobicContact CB-CE3 4.37Å; L233-W290 HydrophobicContact CB-CG 3.86Å; L233-W290 HydrophobicContact CB-CZ2 4.35Å; L233-W290 HydrophobicContact CD2-CB 3.75Å; L233-W290 HydrophobicContact CD2-CD2 4.46Å; L233-W290 HydrophobicContact CD2-CG 3.84Å; L233-W290 HydrophobicContact CG-CG 4.31Å
234L98.8Very high96.4Very high0 Ų028 Ų280%016%0.164CC..EExtended strand (participates in β ladder)trans-106.6125.2169.4-74.2164.6000109.5L145 P148 F232 M251 F252 K261 L262 T263L145-L234 HydrophobicContact CB-CD2 3.72Å; L145-L234 HydrophobicContact CD1-CD2 3.61Å; L145-L234 HydrophobicContact CD1-CG 4.39Å; L145-L234 HydrophobicContact CG-CD2 4.32Å; P148-L234 HydrophobicContact CG-CD2 3.62Å; F232-L234 HydrophobicContact CD2-CD1 3.99Å; F232-L234 HydrophobicContact CD2-CG 3.87Å; F232-L234 HydrophobicContact CE2-CD1 3.5Å; F232-L234 HydrophobicContact CE2-CG 3.93Å; L234-M251 HydrophobicContact CD1-CG 4.46Å; L234-M251 HydrophobicContact CD1-SD 4.23Å; L234-M251 HydrophobicContact CD2-SD 4.08Å; L234-F252 HydrophobicContact CD1-CB 4Å; L234-K261 PolarHBondContact N-O 3.02Å; L234-L262 HydrophobicContact CB-CB 4.38Å; L234-L262 HydrophobicContact CB-CD1 3.55Å; L234-L262 HydrophobicContact CD1-CD1 4.4Å; L234-L262 CarbonylContact O-C 3.56Å; L234-L262 WeakPolarHBondContact O-CA 3.32Å; L234-T263 PolarHBondContact O-N 3.45Å
235L98.8Very high96.3Very high1 Ų126.5 Ų26.51%0.00516%0.157CC..EExtended strand (participates in β ladder)trans-116.6124.8170.2-54.9178.4000107.6L145 I146 G147 L233 T263 L272 V283 D286 V287L145-L235 PolarHBondContact O-N 3.47Å; I146-L235 HydrophobicContact CG1-CD1 4.42Å; G147-L235 PolarHBondContact N-O 3.18Å; L233-L235 HydrophobicContact CD1-CD2 3.85Å; L233-L235 HydrophobicContact CD1-CG 4.47Å; L233-L235 HydrophobicContact CD2-CD1 4.24Å; L233-L235 HydrophobicContact CD2-CD2 4.08Å; L233-L235 HydrophobicContact CD2-CG 4.16Å; L233-L235 HydrophobicContact CG-CD2 3.97Å; L233-L235 HydrophobicContact CG-CG 4.06Å; L235-T263 WeakPolarHBondContact CA-O 3.28Å; L235-T263 HydrophobicContact CD2-CG2 4.35Å; L235-L272 HydrophobicContact CB-CD1 4.01Å; L235-V283 HydrophobicContact CD1-CB 4.41Å; L235-V283 HydrophobicContact CD1-CG1 3.82Å; L235-D286 HydrophobicContact CD1-CB 4.47Å; L235-D286 HydrophobicContact CD2-CB 4.35Å; L235-V287 HydrophobicContact CD1-CG2 3.86Å
236H98.6Very high96.2Very high0 Ų033 Ų330%018%0.182CC..EExtended strand (participates in β ladder)trans-145.3134.4-176.2-149.2107.1000112.3D240 C243 I245 S248 T263 I264 I265H236-D240 IonicContact NE2-OD2 3.69Å; H236-C243 PolarHBondContact NE2-O 3.46Å; H236-I245 HydrophobicContact CB-CG1 4.38Å; H236-I245 WeakPolarHBondContact NE2-CA 3.44Å; H236-I245 PolarHBondContact NE2-N 3.22Å; H236-S248 PolarHBondContact CE1-OG 2.65Å; H236-S248 PolarHBondContact ND1-OG 2.99Å; H236-T263 PolarHBondContact N-O 3.39Å; H236-I264 CarbonylContact O-C 3.48Å; H236-I264 VanDerWaalsContact O-CA 3.28Å; H236-I264 WeakPolarHBondContact O-CA 3.41Å; H236-I265 PolarHBondContact O-N 3.23Å
237G98Very high96.1Very high1 Ų128.8 Ų28.81%0.0115%0.154CC..EExtended strand (participates in β ladder)trans-85.2131.9175.500000111.4A239 D240 I265 G268G237-A239 PolarHBondContact O-N 3.43Å; G237-D240 WeakPolarHBondContact O-CB 3.38Å; G237-D240 PolarHBondContact O-N 3.27Å; G237-I265 WeakPolarHBondContact CA-O 3.38Å; G237-G268 CarbonylContact C-O 3.53Å; G237-G268 VanDerWaalsContact C-O 3.3Å; G237-G268 WeakPolarHBondContact CA-O 3.29Å
238D96.3Very high96.1Very high78 Ų7826 Ų2642%0.41714%0.135SC..THydrogen-bonded Turntrans-74.8-8.5-178.669.20.1000114.4I245 I264 I265 G267D238-I245 HydrophobicContact CB-CD1 3.93Å; D238-I264 HydrophobicContact CB-CG2 3.95Å; D238-I265 PolarHBondContact N-O 3.22Å; D238-I265 VanDerWaalsContact N-O 3.11Å; D238-G267 WeakPolarHBondContact OD1-CA 3.39Å; D238-G267 PolarHBondContact OD1-N 3.29Å
239A95.3Very high96.1Very high27 Ų2730.1 Ų30.122%0.22315%0.153CC..THydrogen-bonded Turntrans-101.68.7173.100000113.2G237 K241 G268 Y269G237-A239 PolarHBondContact O-N 3.43Å; A239-K241 PolarHBondContact O-N 2.86Å; A239-G268 CarbonylContact C-O 3.51Å; A239-G268 WeakPolarHBondContact CA-O 3.31Å; A239-G268 WeakPolarHBondContact CB-O 3.46Å; A239-G268 PolarHBondContact N-O 3.44Å; A239-G268 VanDerWaalsContact N-O 3.12Å; A239-Y269 HydrophobicContact CB-CD1 3.88Å; A239-Y269 HydrophobicContact CB-CE1 3.91Å
240D94.7Very high96.1Very high12 Ų1228 Ų286%0.06414%0.135CC..  trans-57.7121.3175.3-170.3-19.1000111.2H236 G237 L242 C243 G268 H270H236-D240 IonicContact NE2-OD2 3.69Å; G237-D240 WeakPolarHBondContact O-CB 3.38Å; G237-D240 PolarHBondContact O-N 3.27Å; D240-L242 WeakPolarHBondContact OD1-CA 3.26Å; D240-L242 PolarHBondContact OD1-N 2.95Å; D240-C243 WeakPolarHBondContact CB-O 3.35Å; D240-C243 PolarHBondContact OD1-N 3.42Å; D240-G268 PolarHBondContact N-O 3.32Å; D240-H270 VanDerWaalsContact CG-ND1 3.34Å; D240-H270 IonicContact OD1-CG 3.76Å; D240-H270 IonicContact OD1-ND1 2.67Å; D240-H270 PolarHBondContact OD1-ND1 3.06Å; D240-H270 IonicContact OD2-CE1 3.68Å; D240-H270 IonicContact OD2-CG 3.22Å; D240-H270 IonicContact OD2-ND1 3.89Å; D240-H270 PolarHBondContact OD2-ND1 3.23Å
241K89.4Confident96.1Very high96 Ų9627.8 Ų27.842%0.41713%0.134SC..SBendtrans-95.4-12.2179.2-64.2-58.1-175179.80113.5N153 W184 A239N153-K241 PolarHBondContact ND2-O 3.44Å; W184-K241 HydrophobicContact CB-CB 4.39Å; W184-K241 HydrophobicContact CD2-CB 4.33Å; W184-K241 HydrophobicContact CD2-CG 4.18Å; W184-K241 HydrophobicContact CE3-CB 4.17Å; W184-K241 HydrophobicContact CE3-CG 3.55Å; W184-K241 HydrophobicContact CG-CB 4.44Å; W184-K241 HydrophobicContact CZ3-CG 3.89Å; A239-K241 PolarHBondContact O-N 2.86Å
242L87.6Confident96.1Very high41 Ų4129.4 Ų29.422%0.21514%0.138CC..SBendtrans-99.2-54.6-174.4-59-179000110.9N153 I180 V185 D240 H270N153-L242 PolarHBondContact N-O 3.28Å; I180-L242 HydrophobicContact CG2-CD1 3.89Å; I180-L242 HydrophobicContact CG2-CD2 4.06Å; V185-L242 HydrophobicContact CG2-CD1 4.2Å; D240-L242 WeakPolarHBondContact OD1-CA 3.26Å; D240-L242 PolarHBondContact OD1-N 2.95Å; L242-H270 HydrophobicContact CB-CB 4.5Å; L242-H270 HydrophobicContact CD1-CB 4.05Å; L242-H270 VanDerWaalsContact CD1-CD2 3.45Å; L242-H270 WeakPolarHBondContact CD1-CD2 3.38Å; L242-H270 HydrophobicContact CG-CB 4.42Å
243C92.4Very high96.1Very high4 Ų436 Ų363%0.02717%0.169CC..BIsolated β-bridgetrans-104.2128.4175.7-70.70000109.9M149 H236 D240 I245 H270M149-C243 VanDerWaalsContact CA-SG 3.59Å; H236-C243 PolarHBondContact NE2-O 3.46Å; D240-C243 WeakPolarHBondContact CB-O 3.35Å; D240-C243 PolarHBondContact OD1-N 3.42Å; C243-I245 PolarHBondContact O-N 3.16Å; C243-H270 PolarHBondContact SG-CE1 3Å
244D91.8Very high96.1Very high14 Ų1442 Ų428%0.07520%0.196CC..  trans-78.1125.1-176.7-160.7-59.7000110.6Q151 P154 R246 G247Q151-D244 PolarHBondContact O-N 2.85Å; P154-D244 WeakPolarHBondContact CD-OD2 3.28Å; D244-R246 VanDerWaalsContact CG-NE 3.33Å; D244-R246 PolarHBondContact O-N 3.31Å; D244-R246 WeakPolarHBondContact OD1-CB 3.39Å; D244-R246 WeakPolarHBondContact OD1-CG 3.28Å; D244-R246 IonicContact OD1-CZ 3.45Å; D244-R246 PolarHBondContact OD1-N 2.49Å; D244-R246 IonicContact OD1-NE 2.65Å; D244-R246 PolarHBondContact OD1-NE 2.93Å; D244-R246 IonicContact OD1-NH2 3.32Å; D244-R246 IonicContact OD2-CZ 2.75Å; D244-R246 VanDerWaalsContact OD2-CZ 3.28Å; D244-R246 IonicContact OD2-NE 3.75Å; D244-R246 PolarHBondContact OD2-NE 3.44Å; D244-R246 VanDerWaalsContact OD2-NE 3.11Å; D244-R246 IonicContact OD2-NH2 2.65Å; D244-R246 PolarHBondContact OD2-NH2 3.13Å; D244-G247 PolarHBondContact O-N 2.75Å
245I95.3Very high96Very high26 Ų2642.1 Ų42.113%0.13320%0.196CC..Hα-helixtrans-55.5-26.4176.9-169.7166.7000113.1H236 D238 C243 G247 S248 K249 I264H236-I245 HydrophobicContact CB-CG1 4.38Å; H236-I245 WeakPolarHBondContact NE2-CA 3.44Å; H236-I245 PolarHBondContact NE2-N 3.22Å; D238-I245 HydrophobicContact CB-CD1 3.93Å; C243-I245 PolarHBondContact O-N 3.16Å; I245-G247 PolarHBondContact O-N 3.39Å; I245-S248 PolarHBondContact O-N 2.81Å; I245-S248 VanDerWaalsContact O-N 3.13Å; I245-K249 HydrophobicContact CG1-CG 4.44Å; I245-K249 PolarHBondContact O-N 3.22Å; I245-I264 HydrophobicContact CD1-CD1 4.03Å; I245-I264 HydrophobicContact CD1-CG1 4.07Å; I245-I264 HydrophobicContact CD1-CG2 3.7Å
246R95.6Very high96Very high138 Ų13845.9 Ų45.952%0.52122%0.221SC..Hα-helixtrans-58.2-33.9173.7-68.8177.4-74.6-172.5-9.5112.2P154 D244 K249 M250P154-R246 VanDerWaalsContact CD-NH2 3.29Å; P154-R246 VanDerWaalsContact CG-NH2 3.28Å; D244-R246 VanDerWaalsContact CG-NE 3.33Å; D244-R246 PolarHBondContact O-N 3.31Å; D244-R246 WeakPolarHBondContact OD1-CB 3.39Å; D244-R246 WeakPolarHBondContact OD1-CG 3.28Å; D244-R246 IonicContact OD1-CZ 3.45Å; D244-R246 PolarHBondContact OD1-N 2.49Å; D244-R246 IonicContact OD1-NE 2.65Å; D244-R246 PolarHBondContact OD1-NE 2.93Å; D244-R246 IonicContact OD1-NH2 3.32Å; D244-R246 IonicContact OD2-CZ 2.75Å; D244-R246 VanDerWaalsContact OD2-CZ 3.28Å; D244-R246 IonicContact OD2-NE 3.75Å; D244-R246 PolarHBondContact OD2-NE 3.44Å; D244-R246 VanDerWaalsContact OD2-NE 3.11Å; D244-R246 IonicContact OD2-NH2 2.65Å; D244-R246 PolarHBondContact OD2-NH2 3.13Å; R246-K249 PolarHBondContact O-N 3.46Å; R246-M250 VanDerWaalsContact O-CB 3.23Å; R246-M250 WeakPolarHBondContact O-CB 3.14Å; R246-M250 PolarHBondContact O-N 3.45Å
247G96.3Very high96Very high0 Ų046 Ų460%022%0.222CC..Hα-helixtrans-62.6-46.5174.800000111.9V150 D244 I245 M250 M251V150-G247 WeakPolarHBondContact CG1-O 3.43Å; D244-G247 PolarHBondContact O-N 2.75Å; I245-G247 PolarHBondContact O-N 3.39Å; G247-M250 PolarHBondContact O-N 3.49Å; G247-M251 PolarHBondContact O-N 2.87Å
248S98Very high96Very high1 Ų152.1 Ų52.11%0.00726%0.264CS..Hα-helixtrans-67.3-40.1177.5-700000112.6H236 I245 M251 F252H236-S248 PolarHBondContact CE1-OG 2.65Å; H236-S248 PolarHBondContact ND1-OG 2.99Å; I245-S248 PolarHBondContact O-N 2.81Å; I245-S248 VanDerWaalsContact O-N 3.13Å; S248-M251 PolarHBondContact O-N 2.86Å; S248-F252 WeakPolarHBondContact O-CB 3.38Å; S248-F252 PolarHBondContact O-N 2.96Å
249K98.3Very high96.1Very high86 Ų8650.8 Ų50.837%0.37426%0.257SS..Hα-helixtrans-61.3-46.7173.5-71.7179.2176.4178.50111.6I245 R246 M251 F252 E253 L262I245-K249 HydrophobicContact CG1-CG 4.44Å; I245-K249 PolarHBondContact O-N 3.22Å; R246-K249 PolarHBondContact O-N 3.46Å; K249-M251 PolarHBondContact O-N 3.28Å; K249-F252 PolarHBondContact O-N 3.45Å; K249-E253 WeakPolarHBondContact O-CB 3.35Å; K249-E253 VanDerWaalsContact O-CG 3.29Å; K249-E253 WeakPolarHBondContact O-CG 3.45Å; K249-E253 PolarHBondContact O-N 2.92Å; K249-L262 HydrophobicContact CG-CD2 4.25Å
250M97.9Very high96.3Very high27 Ų2752.6 Ų52.613%0.13326%0.26CS..Hα-helixtrans-59.5-46.4177.4175.6-179.461.900112.2V150 Q151 E222 I225 R246 G247 E253 K254V150-M250 HydrophobicContact CG1-CE 4.09Å; Q151-M250 HydrophobicContact CG-CE 3.97Å; E222-M250 HydrophobicContact CG-CE 3.81Å; I225-M250 HydrophobicContact CD1-CE 3.77Å; I225-M250 HydrophobicContact CD1-CG 4.42Å; R246-M250 VanDerWaalsContact O-CB 3.23Å; R246-M250 WeakPolarHBondContact O-CB 3.14Å; R246-M250 PolarHBondContact O-N 3.45Å; G247-M250 PolarHBondContact O-N 3.49Å; M250-E253 PolarHBondContact O-N 2.79Å; M250-K254 HydrophobicContact CG-CD 3.77Å; M250-K254 HydrophobicContact CG-CG 4.45Å; M250-K254 WeakPolarHBondContact O-CB 3.47Å; M250-K254 WeakPolarHBondContact O-CG 3.18Å; M250-K254 PolarHBondContact O-N 3.39Å
251M98.4Very high96.5Very high0 Ų056.4 Ų56.40%028%0.276CS..Hα-helixtrans-60.3-48.5176.6180-174.4173.700110.8I130 L145 V150 I225 I228 W230 F232 L234 G247 S248 K249 E253 K254 A255I130-M251 HydrophobicContact CD1-CE 4.34Å; I130-M251 HydrophobicContact CD1-SD 3.96Å; I130-M251 HydrophobicContact CG1-CE 4.14Å; I130-M251 HydrophobicContact CG1-SD 4.41Å; L145-M251 HydrophobicContact CD1-CE 3.75Å; L145-M251 HydrophobicContact CD1-SD 4.05Å; V150-M251 HydrophobicContact CG1-CB 4.46Å; V150-M251 HydrophobicContact CG2-SD 4.11Å; I225-M251 HydrophobicContact CD1-CB 4.08Å; I225-M251 HydrophobicContact CG1-CB 4.33Å; I225-M251 HydrophobicContact CG1-CG 4.26Å; I228-M251 HydrophobicContact CD1-CE 3.87Å; I228-M251 HydrophobicContact CG2-CE 4.31Å; W230-M251 HydrophobicContact CH2-CE 3.61Å; W230-M251 HydrophobicContact CZ2-CE 4.47Å; W230-M251 HydrophobicContact CZ3-CE 4.11Å; F232-M251 HydrophobicContact CD1-CE 4.3Å; F232-M251 HydrophobicContact CD2-CE 4.4Å; F232-M251 HydrophobicContact CE1-CE 4.3Å; F232-M251 HydrophobicContact CE2-CE 4.4Å; F232-M251 HydrophobicContact CG-CE 4.36Å; F232-M251 HydrophobicContact CZ-CE 4.34Å; L234-M251 HydrophobicContact CD1-CG 4.46Å; L234-M251 HydrophobicContact CD1-SD 4.23Å; L234-M251 HydrophobicContact CD2-SD 4.08Å; G247-M251 PolarHBondContact O-N 2.87Å; S248-M251 PolarHBondContact O-N 2.86Å; K249-M251 PolarHBondContact O-N 3.28Å; M251-E253 VanDerWaalsContact C-N 3.33Å; M251-E253 PolarHBondContact O-N 3.49Å; M251-K254 PolarHBondContact O-N 2.92Å; M251-A255 WeakPolarHBondContact O-CB 3.4Å; M251-A255 PolarHBondContact O-N 3.19Å
252F98.7Very high96.9Very high65 Ų6553.7 Ų53.729%0.28527%0.266SS..Hα-helixtrans-59.3-42.8179-177.9-99.8000112.4F232 L234 S248 K249 K260 L262F232-F252 HydrophobicContact CE2-CD2 4.22Å; L234-F252 HydrophobicContact CD1-CB 4Å; S248-F252 WeakPolarHBondContact O-CB 3.38Å; S248-F252 PolarHBondContact O-N 2.96Å; K249-F252 PolarHBondContact O-N 3.45Å; F252-K260 HydrophobicContact CD2-CB 4.3Å; F252-K260 HydrophobicContact CD2-CD 4.17Å; F252-K260 HydrophobicContact CD2-CG 4.23Å; F252-K260 HydrophobicContact CE2-CB 4.12Å; F252-K260 HydrophobicContact CE2-CD 4.17Å; F252-K260 HydrophobicContact CE2-CG 3.84Å; F252-K260 WeakPolarHBondContact O-CD 3.3Å; F252-K260 WeakPolarHBondContact O-CE 3.21Å; F252-K260 PolarHBondContact O-NZ 3.09Å; F252-L262 HydrophobicContact CB-CB 4.26Å; F252-L262 HydrophobicContact CB-CD2 4.05Å; F252-L262 HydrophobicContact CD1-CB 4.26Å; F252-L262 HydrophobicContact CD1-CD2 4.3Å; F252-L262 HydrophobicContact CD2-CB 3.54Å; F252-L262 HydrophobicContact CE2-CB 3.88Å; F252-L262 HydrophobicContact CG-CB 3.75Å; F252-L262 HydrophobicContact CG-CD2 4.11Å; F252-L262 HydrophobicContact CZ-CB 4.38Å
253E98.4Very high97.4Very high139 Ų13953 Ų5365%0.6526%0.263SS*.Hα-helixtrans-69.8-44.9-179.4-73.4168.8-169.100112.5K249 M250 M251K249-E253 WeakPolarHBondContact O-CB 3.35Å; K249-E253 VanDerWaalsContact O-CG 3.29Å; K249-E253 WeakPolarHBondContact O-CG 3.45Å; K249-E253 PolarHBondContact O-N 2.92Å; M250-E253 PolarHBondContact O-N 2.79Å; M251-E253 VanDerWaalsContact C-N 3.33Å; M251-E253 PolarHBondContact O-N 3.49Å
254K98.5Very high97.7Very high127 Ų12756.3 Ų56.355%0.55228%0.28SS*.Hα-helixtrans-93.8-20.3-168.4-64.7-178.8-176.6173.50114.9I225 M250 M251I225-K254 HydrophobicContact CG2-CB 3.53Å; M250-K254 HydrophobicContact CG-CD 3.77Å; M250-K254 HydrophobicContact CG-CG 4.45Å; M250-K254 WeakPolarHBondContact O-CB 3.47Å; M250-K254 WeakPolarHBondContact O-CG 3.18Å; M250-K254 PolarHBondContact O-N 3.39Å; M251-K254 PolarHBondContact O-N 2.92Å
255A98.6Very high98Very high2 Ų256.7 Ų56.72%0.01728%0.282CS..  trans-69.6131.2178.200000111.3I225 I228 F232 M251 S257 K260I225-A255 HydrophobicContact CG2-CB 4.46Å; I225-A255 WeakPolarHBondContact O-CA 3.24Å; I228-A255 HydrophobicContact CB-CB 3.88Å; I228-A255 HydrophobicContact CG2-CB 3.96Å; F232-A255 HydrophobicContact CE1-CB 3.88Å; F232-A255 HydrophobicContact CZ-CB 4.03Å; M251-A255 WeakPolarHBondContact O-CB 3.4Å; M251-A255 PolarHBondContact O-N 3.19Å; A255-S257 PolarHBondContact O-N 3.26Å; A255-K260 PolarHBondContact O-NZ 2.75Å
256P98.4Very high98.1Very high79 Ų7963.6 Ų63.651%0.51331%0.313SS..  trans-76.12.3-179.531.7-38.9000115.1P226 I228 S258P226-P256 WeakPolarHBondContact O-CD 3.46Å; P226-P256 WeakPolarHBondContact O-CG 3.35Å; I228-P256 WeakPolarHBondContact O-CD 3.47Å; I228-P256 WeakPolarHBondContact O-CG 3.49Å; P256-S258 PolarHBondContact O-N 3.18Å
257S98.6Very high98.2Very high4 Ų458.2 Ų58.23%0.02830%0.301CS..  trans-52.6129177.2-1760000112.3I228 S229 W230 A255 D259 K260I228-S257 PolarHBondContact O-N 3.14Å; S229-S257 PolarHBondContact O-OG 3.33Å; W230-S257 VanDerWaalsContact O-CB 3.3Å; W230-S257 WeakPolarHBondContact O-CB 3.42Å; W230-S257 PolarHBondContact O-OG 2.9Å; A255-S257 PolarHBondContact O-N 3.26Å; S257-D259 VanDerWaalsContact C-N 3.31Å; S257-D259 PolarHBondContact OG-N 2.81Å; S257-D259 PolarHBondContact OG-O 3.12Å; S257-K260 WeakPolarHBondContact O-CD 3.39Å; S257-K260 WeakPolarHBondContact O-CE 3.49Å
258S97.9Very high98.2Very high128 Ų12858.2 Ų58.290%0.89530%0.301SS*.SBendtrans-78.8-17.3176.156.90000112.9P256P256-S258 PolarHBondContact O-N 3.18Å
259D98.4Very high98.1Very high51 Ų5161.1 Ų61.127%0.27331%0.313SS..SBendtrans-121.881.9-179.8-176.415.7000110.2P231 F232 S257 R294P231-D259 CarbonylContact C-O 3.54Å; P231-D259 WeakPolarHBondContact CA-O 3.44Å; P231-D259 HydrophobicContact CB-CB 3.98Å; P231-D259 HydrophobicContact CG-CB 4.24Å; F232-D259 PolarHBondContact N-O 3.06Å; S257-D259 VanDerWaalsContact C-N 3.31Å; S257-D259 PolarHBondContact OG-N 2.81Å; S257-D259 PolarHBondContact OG-O 3.12Å; D259-R294 IonicContact OD1-CZ 2.71Å; D259-R294 IonicContact OD1-NE 3.19Å; D259-R294 IonicContact OD1-NH2 3.7Å; D259-R294 PolarHBondContact OD1-NH2 3.24Å; D259-R294 IonicContact OD2-CZ 3.66Å; D259-R294 VanDerWaalsContact OD2-CZ 3.25Å; D259-R294 IonicContact OD2-NE 3.61Å; D259-R294 PolarHBondContact OD2-NE 3.15Å; D259-R294 IonicContact OD2-NH2 3.38Å; D259-R294 PolarHBondContact OD2-NH2 3.3Å
260K98.6Very high98Very high64 Ų6457.4 Ų57.428%0.27830%0.296SS..EExtended strand (participates in β ladder)trans-133.5138.4-178.656.1-179.2176.7178.10111.4F232 F252 A255 S257F232-K260 HydrophobicContact CD1-CB 4.1Å; F232-K260 HydrophobicContact CD2-CB 4.01Å; F232-K260 HydrophobicContact CE1-CB 3.66Å; F232-K260 HydrophobicContact CE1-CD 4.21Å; F232-K260 HydrophobicContact CE2-CB 3.56Å; F232-K260 HydrophobicContact CG-CB 4.27Å; F232-K260 HydrophobicContact CZ-CB 3.37Å; F232-K260 HydrophobicContact CZ-CD 3.75Å; F232-K260 HydrophobicContact CZ-CG 4.19Å; F232-K260 WeakPolarHBondContact O-CA 3.34Å; F252-K260 HydrophobicContact CD2-CB 4.3Å; F252-K260 HydrophobicContact CD2-CD 4.17Å; F252-K260 HydrophobicContact CD2-CG 4.23Å; F252-K260 HydrophobicContact CE2-CB 4.12Å; F252-K260 HydrophobicContact CE2-CD 4.17Å; F252-K260 HydrophobicContact CE2-CG 3.84Å; F252-K260 WeakPolarHBondContact O-CD 3.3Å; F252-K260 WeakPolarHBondContact O-CE 3.21Å; F252-K260 PolarHBondContact O-NZ 3.09Å; A255-K260 PolarHBondContact O-NZ 2.75Å; S257-K260 WeakPolarHBondContact O-CD 3.39Å; S257-K260 WeakPolarHBondContact O-CE 3.49Å
261K98.8Very high97.9Very high92 Ų9256.2 Ų56.240%0.429%0.291SS..EExtended strand (participates in β ladder)trans-131137.9173.2-176.7-179.8173.5-159.60110F232 L233 L234 T263 D286F232-K261 PolarHBondContact O-N 3.16Å; L233-K261 HydrophobicContact CD1-CB 3.89Å; L233-K261 HydrophobicContact CD1-CD 3.88Å; L233-K261 HydrophobicContact CD1-CG 3.93Å; L234-K261 PolarHBondContact N-O 3.02Å; K261-T263 WeakPolarHBondContact CE-OG1 3.35Å; K261-D286 IonicContact NZ-OD2 3.12Å; K261-D286 PolarHBondContact NZ-OD2 2.87Å
262L98.7Very high97.9Very high39 Ų3956.2 Ų56.220%0.20429%0.291CS..EExtended strand (participates in β ladder)trans-119.2121.8168.9172.363.3000108.7L234 K249 F252 I264L234-L262 HydrophobicContact CB-CB 4.38Å; L234-L262 HydrophobicContact CB-CD1 3.55Å; L234-L262 HydrophobicContact CD1-CD1 4.4Å; L234-L262 CarbonylContact O-C 3.56Å; L234-L262 WeakPolarHBondContact O-CA 3.32Å; K249-L262 HydrophobicContact CG-CD2 4.25Å; F252-L262 HydrophobicContact CB-CB 4.26Å; F252-L262 HydrophobicContact CB-CD2 4.05Å; F252-L262 HydrophobicContact CD1-CB 4.26Å; F252-L262 HydrophobicContact CD1-CD2 4.3Å; F252-L262 HydrophobicContact CD2-CB 3.54Å; F252-L262 HydrophobicContact CE2-CB 3.88Å; F252-L262 HydrophobicContact CG-CB 3.75Å; F252-L262 HydrophobicContact CG-CD2 4.11Å; F252-L262 HydrophobicContact CZ-CB 4.38Å; L262-I264 HydrophobicContact CD1-CG1 4.33Å; L262-I264 HydrophobicContact CD2-CD1 4.33Å; L262-I264 HydrophobicContact CD2-CG1 4.34Å; L262-I264 HydrophobicContact CG-CG1 4.14Å
263T98.4Very high97.8Very high27 Ų2753.3 Ų53.317%0.16628%0.278CS..EExtended strand (participates in β ladder)trans-109.8122.5169.2-52.80000108.2L234 L235 H236 K261 I265 D286L234-T263 PolarHBondContact O-N 3.45Å; L235-T263 WeakPolarHBondContact CA-O 3.28Å; L235-T263 HydrophobicContact CD2-CG2 4.35Å; H236-T263 PolarHBondContact N-O 3.39Å; K261-T263 WeakPolarHBondContact CE-OG1 3.35Å; T263-I265 HydrophobicContact CG2-CD1 3.91Å; T263-D286 PolarHBondContact OG1-OD2 3.28Å
264I98.4Very high97.7Very high73 Ų7348.2 Ų48.237%0.37426%0.255SS..EExtended strand (participates in β ladder)trans-100.1127.5173.3-60.2173.8000108H236 D238 I245 L262H236-I264 CarbonylContact O-C 3.48Å; H236-I264 VanDerWaalsContact O-CA 3.28Å; H236-I264 WeakPolarHBondContact O-CA 3.41Å; D238-I264 HydrophobicContact CB-CG2 3.95Å; I245-I264 HydrophobicContact CD1-CD1 4.03Å; I245-I264 HydrophobicContact CD1-CG1 4.07Å; I245-I264 HydrophobicContact CD1-CG2 3.7Å; L262-I264 HydrophobicContact CD1-CG1 4.33Å; L262-I264 HydrophobicContact CD2-CD1 4.33Å; L262-I264 HydrophobicContact CD2-CG1 4.34Å; L262-I264 HydrophobicContact CG-CG1 4.14Å
265I98.1Very high97.5Very high23 Ų2342.2 Ų42.212%0.11823%0.229CC..EExtended strand (participates in β ladder)trans-97.4112.2176.4-52.7-58.7000108.5H236 G237 D238 T263 G267 G268 L272 V279H236-I265 PolarHBondContact O-N 3.23Å; G237-I265 WeakPolarHBondContact CA-O 3.38Å; D238-I265 PolarHBondContact N-O 3.22Å; D238-I265 VanDerWaalsContact N-O 3.11Å; T263-I265 HydrophobicContact CG2-CD1 3.91Å; I265-G267 PolarHBondContact O-N 3.15Å; I265-G268 PolarHBondContact O-N 2.97Å; I265-G268 VanDerWaalsContact O-N 3.07Å; I265-L272 HydrophobicContact CB-CD2 4Å; I265-L272 HydrophobicContact CG1-CD1 3.93Å; I265-L272 HydrophobicContact CG1-CD2 4.06Å; I265-L272 HydrophobicContact CG2-CD2 4.33Å; I265-V279 HydrophobicContact CG2-CG1 3.79Å; I265-V279 HydrophobicContact CG2-CG2 3.92Å
266E97.4Very high97.5Very high170 Ų17044.5 Ų44.579%0.79424%0.24SC*.THydrogen-bonded Turntrans-63.3128177.6-173.5175.8178.200110.8G268E266-G268 PolarHBondContact O-N 3.22Å; E266-G268 VanDerWaalsContact O-N 3.15Å
267G96.4Very high97.4Very high26 Ų2644.7 Ų44.727%0.26824%0.242SC..THydrogen-bonded Turntrans68.60.2-17400000114.8R187 D238 I265 Y269R187-G267 WeakPolarHBondContact CD-O 3.43Å; R187-G267 PolarHBondContact NE-O 2.69Å; R187-G267 PolarHBondContact NH1-O 3.13Å; R187-G267 VanDerWaalsContact NH1-O 3.09Å; D238-G267 WeakPolarHBondContact OD1-CA 3.39Å; D238-G267 PolarHBondContact OD1-N 3.29Å; I265-G267 PolarHBondContact O-N 3.15Å; G267-Y269 WeakPolarHBondContact O-CD1 3.49Å
268G97.3Very high97.3Very high0 Ų050.1 Ų50.10%027%0.266CS..  trans-64.6138.9-178.700000112.2G237 A239 D240 I265 E266 D275G237-G268 CarbonylContact C-O 3.53Å; G237-G268 VanDerWaalsContact C-O 3.3Å; G237-G268 WeakPolarHBondContact CA-O 3.29Å; A239-G268 CarbonylContact C-O 3.51Å; A239-G268 WeakPolarHBondContact CA-O 3.31Å; A239-G268 WeakPolarHBondContact CB-O 3.46Å; A239-G268 PolarHBondContact N-O 3.44Å; A239-G268 VanDerWaalsContact N-O 3.12Å; D240-G268 PolarHBondContact N-O 3.32Å; I265-G268 PolarHBondContact O-N 2.97Å; I265-G268 VanDerWaalsContact O-N 3.07Å; E266-G268 PolarHBondContact O-N 3.22Å; E266-G268 VanDerWaalsContact O-N 3.15Å; G268-D275 WeakPolarHBondContact CA-OD2 3.29Å
269Y96.6Very high97.3Very high62 Ų6244.8 Ų44.824%0.24323%0.228CC..  trans-90.5-164.9176.6-83.528.3000110.8K183 R187 A239 G267 L272 D275K183-Y269 WeakPolarHBondContact O-CE2 3.39Å; R187-Y269 HydrophobicContact CG-CD1 3.51Å; R187-Y269 HydrophobicContact CG-CD2 3.67Å; R187-Y269 HydrophobicContact CG-CE1 3.53Å; R187-Y269 HydrophobicContact CG-CE2 3.67Å; R187-Y269 HydrophobicContact CG-CG 3.59Å; A239-Y269 HydrophobicContact CB-CD1 3.88Å; A239-Y269 HydrophobicContact CB-CE1 3.91Å; G267-Y269 WeakPolarHBondContact O-CD1 3.49Å; Y269-L272 WeakPolarHBondContact O-CD2 3.48Å; Y269-D275 PolarHBondContact N-OD2 2.95Å
270H96.4Very high97.3Very high7 Ų742.9 Ų42.93%0.03222%0.22CC..SBendtrans-68.8-51.7-171.6-173.253.3000113.6H122 S123 V185 D240 L242 C243 L272H122-H270 AromaticContact CE1-CD2 3.65Å; H122-H270 AromaticContact CE1-CE1 3.92Å; H122-H270 AromaticContact CE1-NE2 3.57Å; H122-H270 PolarHBondContact CE1-O 2.86Å; H122-H270 AromaticContact NE2-CD2 3.8Å; H122-H270 AromaticContact NE2-NE2 3.74Å; S123-H270 WeakPolarHBondContact CB-NE2 3.33Å; S123-H270 PolarHBondContact OG-CE1 2.95Å; S123-H270 VanDerWaalsContact OG-CE1 3.31Å; S123-H270 PolarHBondContact OG-NE2 3.33Å; V185-H270 PolarHBondContact O-N 2.79Å; D240-H270 VanDerWaalsContact CG-ND1 3.34Å; D240-H270 IonicContact OD1-CG 3.76Å; D240-H270 IonicContact OD1-ND1 2.67Å; D240-H270 PolarHBondContact OD1-ND1 3.06Å; D240-H270 IonicContact OD2-CE1 3.68Å; D240-H270 IonicContact OD2-CG 3.22Å; D240-H270 IonicContact OD2-ND1 3.89Å; D240-H270 PolarHBondContact OD2-ND1 3.23Å; L242-H270 HydrophobicContact CB-CB 4.5Å; L242-H270 HydrophobicContact CD1-CB 4.05Å; L242-H270 VanDerWaalsContact CD1-CD2 3.45Å; L242-H270 WeakPolarHBondContact CD1-CD2 3.38Å; L242-H270 HydrophobicContact CG-CB 4.42Å; C243-H270 PolarHBondContact SG-CE1 3Å; H270-L272 PolarHBondContact O-N 2.87Å; H270-L272 VanDerWaalsContact O-N 3.15Å
271A95.1Very high97.3Very high3 Ų343.9 Ų43.93%0.02523%0.225CC..  trans-90.368.7-177.600000110.7V185 H273 H274 D275V185-A271 HydrophobicContact CG1-CB 3.5Å; V185-A271 PolarHBondContact O-N 3.36Å; A271-H273 PolarHBondContact O-N 2.68Å; A271-H274 HydrophobicContact CB-CB 4.45Å; A271-H274 CarbonylContact O-C 3.56Å; A271-H274 WeakPolarHBondContact O-CA 3.43Å; A271-H274 PolarHBondContact O-N 3.14Å; A271-D275 PolarHBondContact O-N 3.01Å
272L97.8Very high97.2Very high0 Ų042.7 Ų42.70%023%0.226CC..G310 helixtrans-51.5-30.3-176-67.8179.2000115.1I146 L235 I265 Y269 H270 H274 D275 V279 A280 V283I146-L272 HydrophobicContact CG2-CB 3.88Å; I146-L272 HydrophobicContact CG2-CD1 4.36Å; I146-L272 HydrophobicContact CG2-CG 4.47Å; L235-L272 HydrophobicContact CB-CD1 4.01Å; I265-L272 HydrophobicContact CB-CD2 4Å; I265-L272 HydrophobicContact CG1-CD1 3.93Å; I265-L272 HydrophobicContact CG1-CD2 4.06Å; I265-L272 HydrophobicContact CG2-CD2 4.33Å; Y269-L272 WeakPolarHBondContact O-CD2 3.48Å; H270-L272 PolarHBondContact O-N 2.87Å; H270-L272 VanDerWaalsContact O-N 3.15Å; L272-H274 VanDerWaalsContact C-N 3.26Å; L272-H274 PolarHBondContact O-N 3.37Å; L272-D275 PolarHBondContact O-N 2.91Å; L272-V279 HydrophobicContact CD2-CG1 4.1Å; L272-A280 WeakPolarHBondContact O-CA 3.29Å; L272-V283 HydrophobicContact CB-CG1 4.45Å; L272-V283 HydrophobicContact CB-CG2 3.72Å; L272-V283 HydrophobicContact CD1-CG2 4.46Å
273H96.6Very high97.2Very high3 Ų341 Ų411%0.01422%0.217CC..G310 helixtrans-76.7-12.6178.757.1-75000113.4I62 H122 I146 A271 A280 V283I62-H273 HydrophobicContact CD1-CB 4.03Å; H122-H273 AromaticContact CD2-CE1 3.67Å; H122-H273 AromaticContact CG-CE1 3.55Å; H122-H273 AromaticContact ND1-CE1 3.82Å; I146-H273 HydrophobicContact CD1-CB 4.35Å; A271-H273 PolarHBondContact O-N 2.68Å; H273-A280 WeakPolarHBondContact O-CB 3.22Å; H273-V283 HydrophobicContact CB-CG1 3.99Å
274H96.2Very high97.2Very high33 Ų3339.8 Ų39.815%0.15321%0.21CC..G310 helixtrans-127.725.3172.5-60.6147.1000111.1P58 S186 Q191 A271 L272P58-H274 PolarHBondContact O-CE1 3.01Å; P58-H274 PolarHBondContact O-NE2 3.33Å; S186-H274 VanDerWaalsContact CB-O 3.3Å; S186-H274 WeakPolarHBondContact CB-O 3.21Å; S186-H274 PolarHBondContact OG-O 3.41Å; Q191-H274 HydrophobicContact CB-CB 4.23Å; Q191-H274 WeakPolarHBondContact CB-O 3.47Å; Q191-H274 HydrophobicContact CG-CB 4.1Å; Q191-H274 VanDerWaalsContact CG-O 3.3Å; Q191-H274 WeakPolarHBondContact CG-O 3.31Å; A271-H274 HydrophobicContact CB-CB 4.45Å; A271-H274 CarbonylContact O-C 3.56Å; A271-H274 WeakPolarHBondContact O-CA 3.43Å; A271-H274 PolarHBondContact O-N 3.14Å; L272-H274 VanDerWaalsContact C-N 3.26Å; L272-H274 PolarHBondContact O-N 3.37Å
275D95.8Very high97.2Very high1 Ų142.4 Ų42.41%0.00522%0.218CC..SBendtrans-81.3-163.6172-157.6-13.6000109.2S186 R187 G268 Y269 A271 L272 V279S186-D275 WeakPolarHBondContact OG-CA 3.2Å; R187-D275 WeakPolarHBondContact CB-OD1 3.11Å; R187-D275 IonicContact CZ-OD1 3.87Å; R187-D275 IonicContact CZ-OD2 3.45Å; R187-D275 PolarHBondContact N-OD1 3.23Å; R187-D275 IonicContact NE-OD1 2.64Å; R187-D275 PolarHBondContact NE-OD1 2.72Å; R187-D275 IonicContact NE-OD2 2.82Å; R187-D275 PolarHBondContact NE-OD2 3.45Å; R187-D275 IonicContact NH2-OD1 3.94Å; R187-D275 PolarHBondContact NH2-OD1 3.35Å; R187-D275 IonicContact NH2-OD2 3.61Å; R187-D275 PolarHBondContact NH2-OD2 2.97Å; G268-D275 WeakPolarHBondContact CA-OD2 3.29Å; Y269-D275 PolarHBondContact N-OD2 2.95Å; A271-D275 PolarHBondContact O-N 3.01Å; L272-D275 PolarHBondContact O-N 2.91Å; D275-V279 HydrophobicContact CB-CB 4.23Å; D275-V279 HydrophobicContact CB-CG1 3.9Å
276L97.6Very high97.2Very high50 Ų5043 Ų4326%0.26222%0.221SC..SBendtrans-47142.9175.4-61.4179000112R187 D188 E278 V279 A280R187-L276 HydrophobicContact CB-CD2 3.92Å; R187-L276 HydrophobicContact CB-CG 4.01Å; D188-L276 HydrophobicContact CB-CD2 4.45Å; L276-E278 PolarHBondContact O-N 3.49Å; L276-V279 WeakPolarHBondContact O-CA 3.3Å; L276-V279 WeakPolarHBondContact O-CB 3.42Å; L276-V279 PolarHBondContact O-N 3.33Å; L276-A280 PolarHBondContact O-N 3.01Å
277P96.9Very high97.3Very high83 Ų8334.9 Ų34.954%0.53918%0.184SC..Hα-helixtrans-50.5-39.5-171.8-31.235.9000115E281P277-E281 WeakPolarHBondContact O-CB 3.43Å; P277-E281 PolarHBondContact O-N 3.23Å
278E96.9Very high97.4Very high118 Ų11834.2 Ų34.255%0.55117%0.174SC*.Hα-helixtrans-68.1-32.7177.265-84-164.700113.7L276 T282L276-E278 PolarHBondContact O-N 3.49Å; E278-T282 WeakPolarHBondContact O-CB 3.47Å; E278-T282 PolarHBondContact O-N 2.77Å; E278-T282 PolarHBondContact O-OG1 3.03Å
279V97.8Very high97.4Very high16 Ų1636.5 Ų36.510%0.09719%0.19CC..Hα-helixtrans-74.6-47174.7171.20000110.1I265 L272 D275 L276 E281 T282 V283I265-V279 HydrophobicContact CG2-CG1 3.79Å; I265-V279 HydrophobicContact CG2-CG2 3.92Å; L272-V279 HydrophobicContact CD2-CG1 4.1Å; D275-V279 HydrophobicContact CB-CB 4.23Å; D275-V279 HydrophobicContact CB-CG1 3.9Å; L276-V279 WeakPolarHBondContact O-CA 3.3Å; L276-V279 WeakPolarHBondContact O-CB 3.42Å; L276-V279 PolarHBondContact O-N 3.33Å; V279-E281 PolarHBondContact O-N 3.47Å; V279-T282 WeakPolarHBondContact O-CB 3.22Å; V279-T282 PolarHBondContact O-N 3.09Å; V279-V283 HydrophobicContact CG1-CG2 4.22Å; V279-V283 WeakPolarHBondContact O-CB 3.42Å; V279-V283 WeakPolarHBondContact O-CG2 3.3Å; V279-V283 PolarHBondContact O-N 3.04Å
280A97.7Very high97.5Very high11 Ų1134.1 Ų34.19%0.09118%0.181CC..Hα-helixtrans-56.8-48.6176.300000111.2L272 H273 L276 T282 V283 L284L272-A280 WeakPolarHBondContact O-CA 3.29Å; H273-A280 WeakPolarHBondContact O-CB 3.22Å; L276-A280 PolarHBondContact O-N 3.01Å; A280-T282 VanDerWaalsContact C-N 3.34Å; A280-T282 PolarHBondContact O-N 2.74Å; A280-V283 PolarHBondContact O-N 2.98Å; A280-L284 WeakPolarHBondContact O-CB 3.42Å; A280-L284 WeakPolarHBondContact O-CD1 3.42Å; A280-L284 WeakPolarHBondContact O-CG 3.07Å; A280-L284 PolarHBondContact O-N 3.04Å
281E98.1Very high97.6Very high85 Ų8533.8 Ų33.840%0.39718%0.18SC..Hα-helixtrans-59-44.1176.4178.558.1-139.800112R65 P277 V279 V283 L284 K285R65-E281 IonicContact CZ-OE1 3.3Å; R65-E281 IonicContact CZ-OE2 2.81Å; R65-E281 IonicContact NH1-OE1 2.72Å; R65-E281 PolarHBondContact NH1-OE1 2.95Å; R65-E281 IonicContact NH1-OE2 3.49Å; R65-E281 PolarHBondContact NH1-OE2 3.12Å; R65-E281 IonicContact NH2-OE1 3.73Å; R65-E281 IonicContact NH2-OE2 3.24Å; R65-E281 PolarHBondContact NH2-OE2 2.88Å; P277-E281 WeakPolarHBondContact O-CB 3.43Å; P277-E281 PolarHBondContact O-N 3.23Å; V279-E281 PolarHBondContact O-N 3.47Å; E281-V283 VanDerWaalsContact C-N 3.34Å; E281-V283 PolarHBondContact O-N 2.61Å; E281-L284 PolarHBondContact O-N 3.31Å; E281-K285 VanDerWaalsContact O-CB 3.29Å; E281-K285 WeakPolarHBondContact O-CB 3.38Å; E281-K285 PolarHBondContact O-N 2.82Å
282T97.8Very high97.7Very high67 Ų6735.3 Ų35.341%0.41119%0.188SC..Hα-helixtrans-60.6-45.2177.6-62.70000111.1E278 V279 A280 K285 D286E278-T282 WeakPolarHBondContact O-CB 3.47Å; E278-T282 PolarHBondContact O-N 2.77Å; E278-T282 PolarHBondContact O-OG1 3.03Å; V279-T282 WeakPolarHBondContact O-CB 3.22Å; V279-T282 PolarHBondContact O-N 3.09Å; A280-T282 VanDerWaalsContact C-N 3.34Å; A280-T282 PolarHBondContact O-N 2.74Å; T282-K285 PolarHBondContact O-N 3.28Å; T282-D286 WeakPolarHBondContact O-CB 3.45Å; T282-D286 PolarHBondContact O-N 2.75Å
283V98.2Very high97.7Very high2 Ų241.3 Ų41.31%0.01222%0.22CC..Hα-helixtrans-64-48.4178.8167.50000110.8I146 L235 L272 H273 V279 A280 E281 K285 D286 V287I146-V283 HydrophobicContact CD1-CG1 4.26Å; L235-V283 HydrophobicContact CD1-CB 4.41Å; L235-V283 HydrophobicContact CD1-CG1 3.82Å; L272-V283 HydrophobicContact CB-CG1 4.45Å; L272-V283 HydrophobicContact CB-CG2 3.72Å; L272-V283 HydrophobicContact CD1-CG2 4.46Å; H273-V283 HydrophobicContact CB-CG1 3.99Å; V279-V283 HydrophobicContact CG1-CG2 4.22Å; V279-V283 WeakPolarHBondContact O-CB 3.42Å; V279-V283 WeakPolarHBondContact O-CG2 3.3Å; V279-V283 PolarHBondContact O-N 3.04Å; A280-V283 PolarHBondContact O-N 2.98Å; E281-V283 VanDerWaalsContact C-N 3.34Å; E281-V283 PolarHBondContact O-N 2.61Å; V283-K285 VanDerWaalsContact C-N 3.3Å; V283-K285 PolarHBondContact O-N 3.05Å; V283-D286 PolarHBondContact O-N 2.81Å; V283-V287 HydrophobicContact CG1-CG2 4.33Å; V283-V287 WeakPolarHBondContact O-CB 3.44Å; V283-V287 WeakPolarHBondContact O-CG2 3.49Å; V283-V287 PolarHBondContact O-N 3.27Å
284L98.4Very high97.8Very high3 Ų343.9 Ų43.92%0.01623%0.23CC..Hα-helixtrans-59.8-41.1178.6-73164000112.1E61 I62 A280 E281 T288E61-L284 HydrophobicContact CB-CD2 4.41Å; E61-L284 HydrophobicContact CG-CD1 3.84Å; E61-L284 HydrophobicContact CG-CD2 4.14Å; E61-L284 WeakPolarHBondContact OE1-CD1 3.48Å; I62-L284 HydrophobicContact CB-CD2 4.23Å; I62-L284 HydrophobicContact CG1-CD2 3.38Å; A280-L284 WeakPolarHBondContact O-CB 3.42Å; A280-L284 WeakPolarHBondContact O-CD1 3.42Å; A280-L284 WeakPolarHBondContact O-CG 3.07Å; A280-L284 PolarHBondContact O-N 3.04Å; E281-L284 PolarHBondContact O-N 3.31Å; L284-T288 VanDerWaalsContact O-CB 3.31Å; L284-T288 WeakPolarHBondContact O-CB 2.97Å; L284-T288 PolarHBondContact O-N 3.49Å; L284-T288 PolarHBondContact O-OG1 3.19Å
285K98.3Very high97.8Very high127 Ų12743.1 Ų43.155%0.55223%0.227SC*.Hα-helixtrans-64.6-49.2174-178.2-178.6174.9-1750111.5E281 T282 V283 V287 T288 S289E281-K285 VanDerWaalsContact O-CB 3.29Å; E281-K285 WeakPolarHBondContact O-CB 3.38Å; E281-K285 PolarHBondContact O-N 2.82Å; T282-K285 PolarHBondContact O-N 3.28Å; V283-K285 VanDerWaalsContact C-N 3.3Å; V283-K285 PolarHBondContact O-N 3.05Å; K285-V287 PolarHBondContact O-N 3.07Å; K285-T288 PolarHBondContact O-N 3.22Å; K285-S289 WeakPolarHBondContact O-CB 3.4Å; K285-S289 PolarHBondContact O-N 3.45Å; K285-S289 PolarHBondContact O-OG 2.91Å
286D98.3Very high97.3Very high35 Ų3546.1 Ų46.119%0.18725%0.246CC..Hα-helixtrans-61-44.1-179.8-97.620.4000111.7L235 K261 T263 T282 V283 W290L235-D286 HydrophobicContact CD1-CB 4.47Å; L235-D286 HydrophobicContact CD2-CB 4.35Å; K261-D286 IonicContact NZ-OD2 3.12Å; K261-D286 PolarHBondContact NZ-OD2 2.87Å; T263-D286 PolarHBondContact OG1-OD2 3.28Å; T282-D286 WeakPolarHBondContact O-CB 3.45Å; T282-D286 PolarHBondContact O-N 2.75Å; V283-D286 PolarHBondContact O-N 2.81Å; D286-W290 WeakPolarHBondContact O-CB 3.35Å; D286-W290 PolarHBondContact O-N 2.91Å
287V98.7Very high96.5Very high1 Ų149.5 Ų49.51%0.00627%0.271CS..Hα-helixtrans-58.1-52174.2172.10000110.4I62 V120 V144 I146 L235 V283 K285 I291I62-V287 HydrophobicContact CG2-CG1 4.33Å; V120-V287 HydrophobicContact CG2-CG1 4.4Å; V144-V287 HydrophobicContact CG1-CB 4.43Å; V144-V287 HydrophobicContact CG1-CG1 4.26Å; V144-V287 HydrophobicContact CG1-CG2 3.85Å; I146-V287 HydrophobicContact CD1-CG2 4.1Å; L235-V287 HydrophobicContact CD1-CG2 3.86Å; V283-V287 HydrophobicContact CG1-CG2 4.33Å; V283-V287 WeakPolarHBondContact O-CB 3.44Å; V283-V287 WeakPolarHBondContact O-CG2 3.49Å; V283-V287 PolarHBondContact O-N 3.27Å; K285-V287 PolarHBondContact O-N 3.07Å; V287-I291 HydrophobicContact CG1-CD1 4.12Å; V287-I291 WeakPolarHBondContact O-CG1 3.37Å; V287-I291 PolarHBondContact O-N 3.35Å
288T98.4Very high95.2Very high11 Ų1149.4 Ų49.47%0.06727%0.273CS..Hα-helixtrans-63.5-50.8-176.1-57.70000111L66 R69 L284 K285 I291 T292L66-T288 HydrophobicContact CD2-CG2 4.4Å; R69-T288 HydrophobicContact CG-CG2 3.88Å; L284-T288 VanDerWaalsContact O-CB 3.31Å; L284-T288 WeakPolarHBondContact O-CB 2.97Å; L284-T288 PolarHBondContact O-N 3.49Å; L284-T288 PolarHBondContact O-OG1 3.19Å; K285-T288 PolarHBondContact O-N 3.22Å; T288-I291 PolarHBondContact O-N 3.39Å; T288-T292 HydrophobicContact CG2-CG2 4.4Å; T288-T292 WeakPolarHBondContact O-CG2 3.46Å; T288-T292 PolarHBondContact O-N 2.93Å; T288-T292 PolarHBondContact O-OG1 3.37Å; T288-T292 VanDerWaalsContact O-OG1 3.08Å
289S98.2Very high93.4Very high48 Ų4849.4 Ų49.434%0.33629%0.286SS..Hα-helixtrans-61.6-46.6-179.3-71.90000111.8K285 I291 T292 D293K285-S289 WeakPolarHBondContact O-CB 3.4Å; K285-S289 PolarHBondContact O-N 3.45Å; K285-S289 PolarHBondContact O-OG 2.91Å; S289-I291 VanDerWaalsContact C-N 3.3Å; S289-I291 PolarHBondContact O-N 3.24Å; S289-T292 WeakPolarHBondContact CA-OG1 3.37Å; S289-T292 PolarHBondContact O-N 3.5Å; S289-T292 VanDerWaalsContact O-N 3.15Å; S289-T292 PolarHBondContact O-OG1 3.47Å; S289-D293 WeakPolarHBondContact O-CB 3.35Å; S289-D293 PolarHBondContact O-N 2.95Å
290W98.7Very high91.1Very high13 Ų1353.7 Ų53.75%0.04931%0.312CS..Hα-helixtrans-61.1-39.2-178.4-17197.5000112.5F118 V144 P231 L233 D286 R294F118-W290 HydrophobicContact CD1-CZ3 4.19Å; F118-W290 HydrophobicContact CE1-CZ3 4.23Å; V144-W290 HydrophobicContact CG2-CD2 4.39Å; V144-W290 HydrophobicContact CG2-CE3 3.59Å; V144-W290 HydrophobicContact CG2-CZ3 3.87Å; P231-W290 HydrophobicContact CB-CH2 4Å; P231-W290 HydrophobicContact CB-CZ2 4.17Å; L233-W290 HydrophobicContact CB-CD2 3.76Å; L233-W290 HydrophobicContact CB-CE3 4.37Å; L233-W290 HydrophobicContact CB-CG 3.86Å; L233-W290 HydrophobicContact CB-CZ2 4.35Å; L233-W290 HydrophobicContact CD2-CB 3.75Å; L233-W290 HydrophobicContact CD2-CD2 4.46Å; L233-W290 HydrophobicContact CD2-CG 3.84Å; L233-W290 HydrophobicContact CG-CG 4.31Å; D286-W290 WeakPolarHBondContact O-CB 3.35Å; D286-W290 PolarHBondContact O-N 2.91Å; W290-R294 VanDerWaalsContact CZ2-CZ 3.46Å; W290-R294 VanDerWaalsContact NE1-CZ 3.27Å; W290-R294 PolarHBondContact O-NH1 2.94Å
291I98.6Very high88.7Confident0 Ų058.2 Ų58.20%034%0.341CS..Hα-helixtrans-69.3-47.1174.4-67172.7000110.4L66 L71 F118 V120 V144 V287 T288 S289 D293 R294 L295L66-I291 HydrophobicContact CD1-CD1 4.11Å; L66-I291 HydrophobicContact CD2-CB 4.41Å; L66-I291 HydrophobicContact CD2-CD1 3.85Å; L66-I291 HydrophobicContact CD2-CG2 4.5Å; L71-I291 HydrophobicContact CD2-CG2 3.41Å; L71-I291 VanDerWaalsContact CD2-CG2 3.41Å; F118-I291 HydrophobicContact CD1-CG1 4.19Å; F118-I291 HydrophobicContact CD1-CG2 4.17Å; F118-I291 HydrophobicContact CD2-CG2 3.95Å; F118-I291 HydrophobicContact CE1-CG2 4.23Å; F118-I291 HydrophobicContact CE2-CG2 4.02Å; F118-I291 HydrophobicContact CG-CG1 4.48Å; F118-I291 HydrophobicContact CG-CG2 4.03Å; F118-I291 HydrophobicContact CZ-CG2 4.15Å; V120-I291 HydrophobicContact CG2-CD1 3.94Å; V144-I291 HydrophobicContact CG2-CD1 4.05Å; V144-I291 HydrophobicContact CG2-CG1 3.88Å; V287-I291 HydrophobicContact CG1-CD1 4.12Å; V287-I291 WeakPolarHBondContact O-CG1 3.37Å; V287-I291 PolarHBondContact O-N 3.35Å; T288-I291 PolarHBondContact O-N 3.39Å; S289-I291 VanDerWaalsContact C-N 3.3Å; S289-I291 PolarHBondContact O-N 3.24Å; I291-D293 VanDerWaalsContact C-N 3.3Å; I291-D293 PolarHBondContact O-N 3.48Å; I291-R294 PolarHBondContact O-N 2.9Å; I291-R294 VanDerWaalsContact O-N 3.11Å; I291-L295 PolarHBondContact O-N 3.08Å
292T97.7Very high86Confident34 Ų3459.7 Ų59.721%0.20936%0.358CS..Hα-helixtrans-64.9-32.6-176.5530000113.6R69 T288 S289 R294 L295R69-T292 HydrophobicContact CB-CG2 3.86Å; R69-T292 HydrophobicContact CG-CG2 3.79Å; T288-T292 HydrophobicContact CG2-CG2 4.4Å; T288-T292 WeakPolarHBondContact O-CG2 3.46Å; T288-T292 PolarHBondContact O-N 2.93Å; T288-T292 PolarHBondContact O-OG1 3.37Å; T288-T292 VanDerWaalsContact O-OG1 3.08Å; S289-T292 WeakPolarHBondContact CA-OG1 3.37Å; S289-T292 PolarHBondContact O-N 3.5Å; S289-T292 VanDerWaalsContact O-N 3.15Å; S289-T292 PolarHBondContact O-OG1 3.47Å; T292-R294 PolarHBondContact O-N 3.39Å; T292-L295 HydrophobicContact CG2-CD1 4.19Å; T292-L295 WeakPolarHBondContact O-CB 3.26Å; T292-L295 PolarHBondContact O-N 3.36Å
293D97.8Very high83.5Confident126 Ų12665.3 Ų65.367%0.67438%0.379SS*.THydrogen-bonded Turntrans-68.1-16.7178-67.6-12.6000112.5S289 I291S289-D293 WeakPolarHBondContact O-CB 3.35Å; S289-D293 PolarHBondContact O-N 2.95Å; I291-D293 VanDerWaalsContact C-N 3.3Å; I291-D293 PolarHBondContact O-N 3.48Å
294R97.6Very high81Confident57 Ų5774.1 Ų74.122%0.21542%0.42CS..THydrogen-bonded Turntrans-104.47.1178.1-73.3167.1-175.668.16.4113.3F118 T141 D259 W290 I291 T292F118-R294 HydrophobicContact CE1-CB 3.92Å; F118-R294 HydrophobicContact CZ-CB 3.82Å; T141-R294 HydrophobicContact CG2-CB 4.39Å; D259-R294 IonicContact OD1-CZ 2.71Å; D259-R294 IonicContact OD1-NE 3.19Å; D259-R294 IonicContact OD1-NH2 3.7Å; D259-R294 PolarHBondContact OD1-NH2 3.24Å; D259-R294 IonicContact OD2-CZ 3.66Å; D259-R294 VanDerWaalsContact OD2-CZ 3.25Å; D259-R294 IonicContact OD2-NE 3.61Å; D259-R294 PolarHBondContact OD2-NE 3.15Å; D259-R294 IonicContact OD2-NH2 3.38Å; D259-R294 PolarHBondContact OD2-NH2 3.3Å; W290-R294 VanDerWaalsContact CZ2-CZ 3.46Å; W290-R294 VanDerWaalsContact NE1-CZ 3.27Å; W290-R294 PolarHBondContact O-NH1 2.94Å; I291-R294 PolarHBondContact O-N 2.9Å; I291-R294 VanDerWaalsContact O-N 3.11Å; T292-R294 PolarHBondContact O-N 3.39Å
295L95.9Very high78.8Confident17 Ų1777.8 Ų77.89%0.08946%0.459CS..SBendtrans-74.2146173.8-66.1175.3000110.4R43 A44 L71 F118 I291 T292R43-L295 HydrophobicContact CB-CD1 4.49Å; R43-L295 HydrophobicContact CB-CD2 4.45Å; A44-L295 HydrophobicContact CB-CD2 3.54Å; L71-L295 HydrophobicContact CD1-CD1 3.97Å; F118-L295 HydrophobicContact CE2-CD2 4.07Å; I291-L295 PolarHBondContact O-N 3.08Å; T292-L295 HydrophobicContact CG2-CD1 4.19Å; T292-L295 WeakPolarHBondContact O-CB 3.26Å; T292-L295 PolarHBondContact O-N 3.36Å
296P86.6Confident76.2Confident64 Ų6480.7 Ų80.742%0.41650%0.495SS..PPolyproline II helixtrans-54.1149.3166.8-23.332.6000110.8R43 P116 S298R43-P296 PolarHBondContact NH2-O 3.07Å; R43-P296 VanDerWaalsContact NH2-O 3.11Å; P116-P296 HydrophobicContact CG-CG 3.59Å; P296-S298 PolarHBondContact O-N 3.2Å
297P79.7Confident75.1Confident121 Ų12183 Ų8379%0.78651%0.51SS*.PPolyproline II helixtrans-49.9136.7171-2331.7000109.8S299P297-S299 PolarHBondContact O-N 2.63Å; P297-S299 VanDerWaalsContact O-N 3.11Å
298S70.3Confident73.9Confident82 Ų8287.3 Ų87.357%0.57354%0.537SS*.PPolyproline II helixtrans-59.5120.8173.753.60000108.4P296 T300P296-S298 PolarHBondContact O-N 3.2Å; S298-T300 PolarHBondContact O-N 3.36Å
299S58.5Low72.5Confident118 Ų11891.5 Ų91.583%0.82556%0.563SS**  trans-67.586.9167.352.20000107.9P297 P301P297-S299 PolarHBondContact O-N 2.63Å; P297-S299 VanDerWaalsContact O-N 3.11Å; S299-P301 WeakPolarHBondContact O-CD 3.44Å
300T48.8Very low71Confident106 Ų10694.1 Ų94.165%0.6558%0.576SS**PPolyproline II helixtrans-61.5123.9167.2-41.90000106.4S298S298-T300 PolarHBondContact O-N 3.36Å
301P48.6Very low69.3Low106 Ų10699.1 Ų99.169%0.68861%0.609SS**PPolyproline II helixtrans-55.2137.6166.1-17.729.8000107.3S299 Q303S299-P301 WeakPolarHBondContact O-CD 3.44Å; P301-Q303 PolarHBondContact O-N 2.91Å
302P41.8Very low67.3Low116 Ų116105.7 Ų105.775%0.75365%0.65SS**PPolyproline II helixtrans-52.6123.2172.319.7-28.3000107.4Q304P302-Q304 PolarHBondContact O-N 2.64Å
303Q44.3Very low65.1Low185 Ų185110.9 Ų110.986%0.86468%0.681SS**  trans-52112167.4-79-179.6-500105.5P301 G305P301-Q303 PolarHBondContact O-N 2.91Å; Q303-G305 PolarHBondContact O-N 3.09Å
304Q45.8Very low62.6Low187 Ų187109.7 Ų109.787%0.87468%0.682SS**  trans-63.398.6166.1-75.3-176.13.500104.9P302 S306P302-Q304 PolarHBondContact O-N 2.64Å; Q304-S306 PolarHBondContact O-N 3.01Å
305G53.2Low59.7Low79 Ų79114.1 Ų114.181%0.81472%0.721SS**  trans-60.8120.8168.300000107.6Q303Q303-G305 PolarHBondContact O-N 3.09Å
306S42.9Very low56.4Low188 Ų188122.9 Ų122.9100%1.31578%0.778SS**  trans-1330160.755.70000107.4Q304Q304-S306 PolarHBondContact O-N 3.01Å

Retrieved 306 of 306 residues in 161.9 ms (Link to these results)