A0A087XIW1_POEFO Loading...

Amino acid transporter

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport. Negatively regulated by ARL6IP5.

AlphaFold DB , UniProt , Accession A0A087XIW1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 524 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	V	37.1	Very low	38.9	Very low	194 Å²	194	175 Å²	175	100%	1.176	88%	0.881	S	S	*	*				0	103.4	0	-168.9	0	0	0	0	105
2	E	35.3	Very low	40.5	Very low	186 Å²	186	168.7 Å²	168.7	87%	0.869	86%	0.858	S	S	*	*			cis	-160.6	147.4	23.2	-142.5	170.6	-179.7	0	0	108.1
3	M	37.6	Very low	42.4	Very low	183 Å²	183	164.5 Å²	164.5	90%	0.901	84%	0.839	S	S	*	*			trans	-68.8	140.9	173	-75.3	-173.8	-116	0	0	111.5
4	M	34.8	Very low	44.1	Very low	190 Å²	190	159.1 Å²	159.1	94%	0.936	82%	0.818	S	S	*	*			trans	-169	101.3	144.2	-103.5	178.3	-169.9	0	0	106.3
5	G	34.3	Very low	45.7	Very low	73 Å²	73	160.6 Å²	160.6	75%	0.753	82%	0.816	S	S	*	*				86.7	44	52.3	0	0	0	0	0	111.5	K7	G5-K7 VanDerWaalsContact C-N 3.29Å; G5-K7 PolarHBondContact O-N 2.95Å
6	I	36.7	Very low	47	Very low	165 Å²	165	152.8 Å²	152.8	85%	0.846	79%	0.787	S	S	*	*			trans	-73.5	91.4	169.8	-59	178.9	0	0	0	107.9	E8	I6-E8 PolarHBondContact O-N 3.11Å; I6-E8 VanDerWaalsContact O-N 3.11Å
7	K	36.8	Very low	47.7	Very low	193 Å²	193	148.6 Å²	148.6	84%	0.839	77%	0.767	S	S	*	*			trans	-73.5	91.4	171.5	-154.3	175.2	-170	175.9	0	107.3	G5 R9	G5-K7 VanDerWaalsContact C-N 3.29Å; G5-K7 PolarHBondContact O-N 2.95Å; K7-R9 PolarHBondContact O-N 3.33Å
8	E	38.8	Very low	48.7	Very low	177 Å²	177	145.6 Å²	145.6	83%	0.827	75%	0.751	S	S	*	*			trans	-57.1	102.6	166.2	-106.3	-174.7	165.1	0	0	108.4	I6 R10	I6-E8 PolarHBondContact O-N 3.11Å; I6-E8 VanDerWaalsContact O-N 3.11Å; E8-R10 PolarHBondContact O-N 2.91Å
9	R	41	Very low	49.7	Very low	238 Å²	238	149.4 Å²	149.4	90%	0.898	76%	0.755	S	S	*	*			trans	-65.6	102.3	165	-77.5	-175	-177.5	-167.4	1.3	106.4	K7 A11	K7-R9 PolarHBondContact O-N 3.33Å; R9-A11 PolarHBondContact O-N 2.77Å
10	R	45.4	Very low	50.2	Low	233 Å²	233	152.3 Å²	152.3	88%	0.879	76%	0.756	S	S	*	*			trans	-56.9	88.2	158.1	-87.1	-177.3	174.1	176.1	-1.1	107.6	E8 V12	E8-R10 PolarHBondContact O-N 2.91Å; R10-V12 VanDerWaalsContact C-N 3.3Å; R10-V12 PolarHBondContact O-N 3Å
11	A	50.4	Low	51	Low	93 Å²	93	146.6 Å²	146.6	77%	0.769	73%	0.728	S	S	*	*			trans	-62.7	100.7	162.5	0	0	0	0	0	105.7	R9 N13	R9-A11 PolarHBondContact O-N 2.77Å; A11-N13 PolarHBondContact O-N 3.39Å
12	V	57.5	Low	52.7	Low	99 Å²	99	143.6 Å²	143.6	60%	0.6	70%	0.696	S	S	*	*			trans	-53.9	117.1	175.2	176.8	0	0	0	0	106.1	R10 V14	R10-V12 VanDerWaalsContact C-N 3.3Å; R10-V12 PolarHBondContact O-N 3Å; V12-V14 WeakPolarHBondContact O-CG2 3.12Å; V12-V14 PolarHBondContact O-N 2.98Å
13	N	64.9	Low	54	Low	114 Å²	114	137 Å²	137	61%	0.61	67%	0.667	S	S	*	*			trans	-69.8	83.5	179.1	-174.4	-11.7	0	0	0	108.4	A11 K15 G16 L17	A11-N13 PolarHBondContact O-N 3.39Å; N13-K15 VanDerWaalsContact C-N 3.26Å; N13-K15 PolarHBondContact O-N 2.93Å; N13-G16 PolarHBondContact O-N 3.19Å; N13-G16 PolarHBondContact OD1-N 3.11Å; N13-G16 VanDerWaalsContact OD1-N 3.11Å; N13-L17 PolarHBondContact O-N 3.03Å
14	V	66.1	Low	55.1	Low	90 Å²	90	129.9 Å²	129.9	55%	0.545	63%	0.632	S	S	.	*	H	α-helix	trans	-58.5	-38.7	-173.1	177.2	0	0	0	0	110.8	V12 L17 L18	V12-V14 WeakPolarHBondContact O-CG2 3.12Å; V12-V14 PolarHBondContact O-N 2.98Å; V14-L17 PolarHBondContact O-N 3.13Å; V14-L18 HydrophobicContact CG1-CD1 3.58Å; V14-L18 WeakPolarHBondContact O-CB 3.24Å; V14-L18 WeakPolarHBondContact O-CD1 3.11Å; V14-L18 PolarHBondContact O-N 2.93Å
15	K	68.9	Low	56.9	Low	181 Å²	181	124.2 Å²	124.2	79%	0.787	61%	0.605	S	S	*	*	H	α-helix	trans	-65.5	-41.1	175.6	-75.2	-175.8	175.8	-180	0	112.4	N13 R19	N13-K15 VanDerWaalsContact C-N 3.26Å; N13-K15 PolarHBondContact O-N 2.93Å; K15-R19 WeakPolarHBondContact O-CB 3.35Å; K15-R19 PolarHBondContact O-N 2.76Å
16	G	65.8	Low	58.9	Low	35 Å²	35	121.8 Å²	121.8	36%	0.361	58%	0.578	S	S	.	*	H	α-helix	trans	-65.7	-40.4	175	0	0	0	0	0	112.6	N13 R20	N13-G16 PolarHBondContact O-N 3.19Å; N13-G16 PolarHBondContact OD1-N 3.11Å; N13-G16 VanDerWaalsContact OD1-N 3.11Å; G16-R20 WeakPolarHBondContact O-CB 3.19Å; G16-R20 PolarHBondContact O-N 3.11Å; G16-R20 VanDerWaalsContact O-N 3.1Å
17	L	59.8	Low	60.3	Low	83 Å²	83	114.2 Å²	114.2	44%	0.435	54%	0.539	S	S	.	.	H	α-helix	trans	-65.7	-44.5	175.7	-163.3	86.5	0	0	0	111.6	N13 V14 R20 N21	N13-L17 PolarHBondContact O-N 3.03Å; V14-L17 PolarHBondContact O-N 3.13Å; L17-R20 PolarHBondContact O-N 2.85Å; L17-N21 WeakPolarHBondContact O-CB 3.41Å; L17-N21 PolarHBondContact O-N 2.79Å; L17-N21 VanDerWaalsContact O-N 3.09Å; L17-N21 PolarHBondContact O-ND2 2.88Å
18	L	65.1	Low	62	Low	93 Å²	93	107.3 Å²	107.3	49%	0.487	51%	0.513	S	S	.	.	H	α-helix	trans	-61.3	-45.4	176.9	-102.8	86.3	0	0	0	111.7	V14 R20 N21 W22 I25	V14-L18 HydrophobicContact CG1-CD1 3.58Å; V14-L18 WeakPolarHBondContact O-CB 3.24Å; V14-L18 WeakPolarHBondContact O-CD1 3.11Å; V14-L18 PolarHBondContact O-N 2.93Å; L18-R20 VanDerWaalsContact C-N 3.33Å; L18-R20 PolarHBondContact O-N 3.18Å; L18-N21 CarbonylContact O-C 3.52Å; L18-N21 PolarHBondContact O-N 3.11Å; L18-W22 VanDerWaalsContact O-CA 3.24Å; L18-W22 WeakPolarHBondContact O-CA 3.18Å; L18-W22 WeakPolarHBondContact O-CB 3.47Å; L18-W22 PolarHBondContact O-N 2.96Å; L18-I25 HydrophobicContact CG-CD1 4.01Å
19	R	67.1	Low	64	Low	219 Å²	219	103.4 Å²	103.4	83%	0.826	50%	0.497	S	S	*	.	H	α-helix	trans	-67.8	-35.3	-178.3	-163	176.6	-176.7	-172.3	0.8	112.1	K15	K15-R19 WeakPolarHBondContact O-CB 3.35Å; K15-R19 PolarHBondContact O-N 2.76Å
20	R	60.1	Low	65.9	Low	207 Å²	207	92.7 Å²	92.7	78%	0.781	46%	0.459	S	S	*	.	H	α-helix	trans	-74.8	-29.7	179.9	-160	168	84.2	172.3	7.1	113	G16 L17 L18	G16-R20 WeakPolarHBondContact O-CB 3.19Å; G16-R20 PolarHBondContact O-N 3.11Å; G16-R20 VanDerWaalsContact O-N 3.1Å; L17-R20 PolarHBondContact O-N 2.85Å; L18-R20 VanDerWaalsContact C-N 3.33Å; L18-R20 PolarHBondContact O-N 3.18Å
21	N	67.1	Low	67.2	Low	32 Å²	32	81.8 Å²	81.8	17%	0.171	42%	0.418	C	S	.	.	T	Hydrogen-bonded Turn	trans	-117	23.4	-174.3	-56.6	-30.1	0	0	0	112.6	L17 L18 L23 L24 I25 M331	L17-N21 WeakPolarHBondContact O-CB 3.41Å; L17-N21 PolarHBondContact O-N 2.79Å; L17-N21 VanDerWaalsContact O-N 3.09Å; L17-N21 PolarHBondContact O-ND2 2.88Å; L18-N21 CarbonylContact O-C 3.52Å; L18-N21 PolarHBondContact O-N 3.11Å; N21-L23 VanDerWaalsContact C-N 3.26Å; N21-L23 PolarHBondContact O-N 3.26Å; N21-L24 PolarHBondContact O-N 3.32Å; N21-I25 HydrophobicContact CB-CD1 4.35Å; N21-I25 WeakPolarHBondContact O-CG1 3.43Å; N21-I25 PolarHBondContact O-N 3.44Å; N21-I25 VanDerWaalsContact O-N 3.11Å; N21-M331 HydrophobicContact CB-CE 3.59Å; N21-M331 WeakPolarHBondContact ND2-CE 3.21Å; N21-M331 VanDerWaalsContact OD1-CE 3.3Å; N21-M331 WeakPolarHBondContact OD1-CE 3.46Å
22	W	73	Confident	68.7	Low	131 Å²	131	82.1 Å²	82.1	50%	0.496	41%	0.407	S	S	.	.	H	α-helix	trans	-58.5	-39.8	-169.5	88.9	-90.1	0	0	0	112	L18 I25 A26	L18-W22 VanDerWaalsContact O-CA 3.24Å; L18-W22 WeakPolarHBondContact O-CA 3.18Å; L18-W22 WeakPolarHBondContact O-CB 3.47Å; L18-W22 PolarHBondContact O-N 2.96Å; W22-I25 PolarHBondContact O-N 3.43Å; W22-A26 HydrophobicContact CE3-CB 3.98Å; W22-A26 HydrophobicContact CZ3-CB 3.97Å; W22-A26 VanDerWaalsContact O-CB 3.23Å; W22-A26 WeakPolarHBondContact O-CB 3.42Å; W22-A26 PolarHBondContact O-N 3.02Å
23	L	61.9	Low	70.2	Confident	48 Å²	48	81 Å²	81	25%	0.251	40%	0.396	S	S	.	.	H	α-helix	trans	-64.6	-45.2	-177.4	-171.2	72.4	0	0	0	111.4	N21 A26 T27 M257 P261	N21-L23 VanDerWaalsContact C-N 3.26Å; N21-L23 PolarHBondContact O-N 3.26Å; L23-A26 PolarHBondContact O-N 3.25Å; L23-T27 PolarHBondContact O-N 3.38Å; L23-T27 PolarHBondContact O-OG1 3.42Å; L23-M257 WeakPolarHBondContact CD1-O 3.25Å; L23-M257 HydrophobicContact CD2-CB 4.16Å; L23-P261 HydrophobicContact CD1-CG 4.21Å
24	L	60.6	Low	71.2	Confident	33 Å²	33	75.6 Å²	75.6	17%	0.173	37%	0.367	C	S	.	.	H	α-helix	trans	-59.3	-50	174.4	160.9	70.1	0	0	0	111.1	N21 A26 T27 V28 M331 R447	N21-L24 PolarHBondContact O-N 3.32Å; L24-A26 VanDerWaalsContact C-N 3.3Å; L24-A26 PolarHBondContact O-N 3.3Å; L24-T27 PolarHBondContact O-N 2.89Å; L24-V28 HydrophobicContact CD1-CG2 3.74Å; L24-V28 HydrophobicContact CG-CG2 4.47Å; L24-V28 WeakPolarHBondContact O-CG2 3.28Å; L24-V28 PolarHBondContact O-N 2.86Å; L24-M331 HydrophobicContact CD2-CE 3.16Å; L24-M331 HydrophobicContact CD2-SD 3.26Å; L24-M331 WeakPolarHBondContact CD2-SD 3.45Å; L24-M331 HydrophobicContact CG-CE 4.48Å; L24-R447 VanDerWaalsContact CD1-NH2 3.29Å
25	I	73	Confident	72	Confident	72 Å²	72	74.4 Å²	74.4	37%	0.369	36%	0.357	S	S	.	.	H	α-helix	trans	-62.9	-42.8	-176.4	-64.4	168.8	0	0	0	109.7	L18 N21 W22 V28 L29	L18-I25 HydrophobicContact CG-CD1 4.01Å; N21-I25 HydrophobicContact CB-CD1 4.35Å; N21-I25 WeakPolarHBondContact O-CG1 3.43Å; N21-I25 PolarHBondContact O-N 3.44Å; N21-I25 VanDerWaalsContact O-N 3.11Å; W22-I25 PolarHBondContact O-N 3.43Å; I25-V28 PolarHBondContact O-N 3.09Å; I25-L29 WeakPolarHBondContact O-CB 3.46Å; I25-L29 PolarHBondContact O-N 3.5Å
26	A	76.1	Confident	72.9	Confident	22 Å²	22	69.2 Å²	69.2	18%	0.182	34%	0.344	C	S	.	.	H	α-helix	trans	-60.4	-46.9	175.5	0	0	0	0	0	111.4	W22 L23 L24 L29 S30 P261	W22-A26 HydrophobicContact CE3-CB 3.98Å; W22-A26 HydrophobicContact CZ3-CB 3.97Å; W22-A26 VanDerWaalsContact O-CB 3.23Å; W22-A26 WeakPolarHBondContact O-CB 3.42Å; W22-A26 PolarHBondContact O-N 3.02Å; L23-A26 PolarHBondContact O-N 3.25Å; L24-A26 VanDerWaalsContact C-N 3.3Å; L24-A26 PolarHBondContact O-N 3.3Å; A26-L29 PolarHBondContact O-N 3.16Å; A26-S30 VanDerWaalsContact O-CB 3.24Å; A26-S30 WeakPolarHBondContact O-CB 3.3Å; A26-S30 PolarHBondContact O-N 3.47Å; A26-S30 PolarHBondContact O-OG 2.85Å; A26-S30 VanDerWaalsContact O-OG 3.08Å; A26-P261 HydrophobicContact CB-CB 3.95Å; A26-P261 HydrophobicContact CB-CG 3.82Å
27	T	65.9	Low	74.1	Confident	5 Å²	5	70.2 Å²	70.2	3%	0.031	34%	0.341	C	S	.	.	H	α-helix	trans	-63.8	-45.5	178.8	-58.1	0	0	0	0	112.4	L23 L24 L29 S30 V31 I264 W443	L23-T27 PolarHBondContact O-N 3.38Å; L23-T27 PolarHBondContact O-OG1 3.42Å; L24-T27 PolarHBondContact O-N 2.89Å; T27-L29 VanDerWaalsContact C-N 3.34Å; T27-L29 PolarHBondContact O-N 3.41Å; T27-S30 WeakPolarHBondContact O-CB 3.35Å; T27-S30 PolarHBondContact O-N 3.42Å; T27-V31 VanDerWaalsContact O-CG2 3.25Å; T27-V31 WeakPolarHBondContact O-CG2 3.38Å; T27-V31 PolarHBondContact O-N 3.06Å; T27-I264 HydrophobicContact CG2-CD1 3.88Å; T27-W443 HydrophobicContact CG2-CB 4.47Å; T27-W443 HydrophobicContact CG2-CE3 4.45Å
28	V	72.8	Confident	75.3	Confident	48 Å²	48	66.3 Å²	66.3	29%	0.291	32%	0.32	S	S	.	.	H	α-helix	trans	-61.5	-45.3	177.3	173.5	0	0	0	0	110.6	L24 I25 V31 L32 W443	L24-V28 HydrophobicContact CD1-CG2 3.74Å; L24-V28 HydrophobicContact CG-CG2 4.47Å; L24-V28 WeakPolarHBondContact O-CG2 3.28Å; L24-V28 PolarHBondContact O-N 2.86Å; I25-V28 PolarHBondContact O-N 3.09Å; V28-V31 PolarHBondContact O-N 3.16Å; V28-L32 HydrophobicContact CG1-CD1 4.31Å; V28-L32 WeakPolarHBondContact O-CG 3.23Å; V28-L32 PolarHBondContact O-N 3.12Å; V28-L32 VanDerWaalsContact O-N 3.08Å; V28-W443 HydrophobicContact CG2-CH2 4.34Å; V28-W443 HydrophobicContact CG2-CZ3 3.79Å
29	L	82.3	Confident	76.3	Confident	95 Å²	95	64.5 Å²	64.5	50%	0.497	31%	0.31	S	S	.	.	H	α-helix	trans	-63.3	-43.5	177.8	-175.9	64	0	0	0	111.2	I25 A26 T27 V31 L32 I33	I25-L29 WeakPolarHBondContact O-CB 3.46Å; I25-L29 PolarHBondContact O-N 3.5Å; A26-L29 PolarHBondContact O-N 3.16Å; T27-L29 VanDerWaalsContact C-N 3.34Å; T27-L29 PolarHBondContact O-N 3.41Å; L29-V31 VanDerWaalsContact C-N 3.29Å; L29-V31 PolarHBondContact O-N 3.03Å; L29-L32 PolarHBondContact O-N 3.4Å; L29-I33 HydrophobicContact CD1-CD1 3.99Å; L29-I33 HydrophobicContact CD1-CG1 4.25Å; L29-I33 HydrophobicContact CD2-CD1 4.28Å; L29-I33 HydrophobicContact CG-CD1 3.68Å; L29-I33 HydrophobicContact CG-CG1 4.31Å; L29-I33 WeakPolarHBondContact O-CB 3.43Å; L29-I33 VanDerWaalsContact O-CG1 3.23Å; L29-I33 WeakPolarHBondContact O-CG1 3.37Å; L29-I33 PolarHBondContact O-N 3.1Å
30	S	80.4	Confident	77.5	Confident	14 Å²	14	57.7 Å²	57.7	10%	0.098	29%	0.293	C	S	.	.	H	α-helix	trans	-59.3	-37.4	175.3	-79.2	0	0	0	0	113.2	A26 T27 G34 P261	A26-S30 VanDerWaalsContact O-CB 3.24Å; A26-S30 WeakPolarHBondContact O-CB 3.3Å; A26-S30 PolarHBondContact O-N 3.47Å; A26-S30 PolarHBondContact O-OG 2.85Å; A26-S30 VanDerWaalsContact O-OG 3.08Å; T27-S30 WeakPolarHBondContact O-CB 3.35Å; T27-S30 PolarHBondContact O-N 3.42Å; S30-G34 WeakPolarHBondContact O-CA 3.36Å; S30-G34 PolarHBondContact O-N 3.35Å; S30-P261 WeakPolarHBondContact CB-O 3.29Å; S30-P261 VanDerWaalsContact OG-C 3.26Å; S30-P261 WeakPolarHBondContact OG-CB 3.19Å; S30-P261 PolarHBondContact OG-O 2.87Å
31	V	71.8	Confident	78.9	Confident	3 Å²	3	48.9 Å²	48.9	2%	0.018	26%	0.262	C	S	.	.	H	α-helix	trans	-66.1	-50.3	174.6	169.9	0	0	0	0	110.5	T27 V28 L29 I33 G34 I35 I264 I268 W443	T27-V31 VanDerWaalsContact O-CG2 3.25Å; T27-V31 WeakPolarHBondContact O-CG2 3.38Å; T27-V31 PolarHBondContact O-N 3.06Å; V28-V31 PolarHBondContact O-N 3.16Å; L29-V31 VanDerWaalsContact C-N 3.29Å; L29-V31 PolarHBondContact O-N 3.03Å; V31-I33 VanDerWaalsContact C-N 3.31Å; V31-I33 PolarHBondContact O-N 2.69Å; V31-G34 PolarHBondContact O-N 2.94Å; V31-I35 HydrophobicContact CG1-CD1 3.78Å; V31-I35 HydrophobicContact CG1-CG1 4.34Å; V31-I35 VanDerWaalsContact O-CG1 3.31Å; V31-I35 WeakPolarHBondContact O-CG1 3.37Å; V31-I35 PolarHBondContact O-N 3.45Å; V31-I264 HydrophobicContact CG2-CG2 3.79Å; V31-I268 HydrophobicContact CB-CD1 4.08Å; V31-I268 HydrophobicContact CG1-CD1 3.9Å; V31-I268 HydrophobicContact CG2-CD1 3.7Å; V31-W443 HydrophobicContact CB-CD2 4.44Å; V31-W443 HydrophobicContact CB-CZ2 4.07Å; V31-W443 HydrophobicContact CG1-CZ2 3.62Å; V31-W443 HydrophobicContact CG2-CD2 3.5Å; V31-W443 VanDerWaalsContact CG2-CD2 3.5Å; V31-W443 VanDerWaalsContact CG2-CE2 3.43Å; V31-W443 HydrophobicContact CG2-CE3 4.16Å; V31-W443 HydrophobicContact CG2-CG 3.65Å; V31-W443 HydrophobicContact CG2-CZ2 4.03Å
32	L	81.7	Confident	79.7	Confident	101 Å²	101	50.5 Å²	50.5	53%	0.529	27%	0.266	S	S	.	.	H	α-helix	trans	-61.1	-42.5	-179.5	-67	173.9	0	0	0	111.5	V28 L29 S36	V28-L32 HydrophobicContact CG1-CD1 4.31Å; V28-L32 WeakPolarHBondContact O-CG 3.23Å; V28-L32 PolarHBondContact O-N 3.12Å; V28-L32 VanDerWaalsContact O-N 3.08Å; L29-L32 PolarHBondContact O-N 3.4Å; L32-S36 WeakPolarHBondContact O-CB 3.33Å; L32-S36 PolarHBondContact O-N 3.26Å; L32-S36 PolarHBondContact O-OG 3.09Å
33	I	89.9	Confident	80.3	Confident	75 Å²	75	51 Å²	51	39%	0.385	27%	0.273	S	S	.	.	H	α-helix	trans	-66.2	-43.7	175	-65.7	171.9	0	0	0	110.4	L29 V31 I35 S36 L37 L265	L29-I33 HydrophobicContact CD1-CD1 3.99Å; L29-I33 HydrophobicContact CD1-CG1 4.25Å; L29-I33 HydrophobicContact CD2-CD1 4.28Å; L29-I33 HydrophobicContact CG-CD1 3.68Å; L29-I33 HydrophobicContact CG-CG1 4.31Å; L29-I33 WeakPolarHBondContact O-CB 3.43Å; L29-I33 VanDerWaalsContact O-CG1 3.23Å; L29-I33 WeakPolarHBondContact O-CG1 3.37Å; L29-I33 PolarHBondContact O-N 3.1Å; V31-I33 VanDerWaalsContact C-N 3.31Å; V31-I33 PolarHBondContact O-N 2.69Å; I33-I35 PolarHBondContact O-N 2.76Å; I33-S36 PolarHBondContact O-N 3.07Å; I33-L37 WeakPolarHBondContact O-CB 3.36Å; I33-L37 PolarHBondContact O-N 2.82Å; I33-L265 HydrophobicContact CB-CD1 4.08Å; I33-L265 HydrophobicContact CG2-CD1 3.65Å; I33-L265 HydrophobicContact CG2-CG 4.24Å
34	G	85	Confident	81.3	Confident	0 Å²	0	57.4 Å²	57.4	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-61.3	-42	178.1	0	0	0	0	0	112.5	S30 V31 G38 L265 A269	S30-G34 WeakPolarHBondContact O-CA 3.36Å; S30-G34 PolarHBondContact O-N 3.35Å; V31-G34 PolarHBondContact O-N 2.94Å; G34-G38 PolarHBondContact O-N 3.09Å; G34-L265 WeakPolarHBondContact CA-O 3.31Å; G34-A269 WeakPolarHBondContact O-CA 3.07Å; G34-A269 VanDerWaalsContact O-CB 3.31Å; G34-A269 WeakPolarHBondContact O-CB 3.43Å
35	I	82.8	Confident	82.3	Confident	66 Å²	66	57.7 Å²	57.7	34%	0.338	30%	0.303	S	S	.	.	H	α-helix	trans	-61.8	-51.6	173.9	-66.1	169.1	0	0	0	110.5	V31 I33 L37 G38 I39 I268 I272	V31-I35 HydrophobicContact CG1-CD1 3.78Å; V31-I35 HydrophobicContact CG1-CG1 4.34Å; V31-I35 VanDerWaalsContact O-CG1 3.31Å; V31-I35 WeakPolarHBondContact O-CG1 3.37Å; V31-I35 PolarHBondContact O-N 3.45Å; I33-I35 PolarHBondContact O-N 2.76Å; I35-L37 VanDerWaalsContact C-N 3.35Å; I35-L37 PolarHBondContact O-N 2.67Å; I35-G38 PolarHBondContact O-N 3.15Å; I35-I39 HydrophobicContact CG2-CD1 3.84Å; I35-I39 WeakPolarHBondContact O-CG1 3.23Å; I35-I39 PolarHBondContact O-N 3.47Å; I35-I268 HydrophobicContact CG1-CG2 3.76Å; I35-I272 VanDerWaalsContact CA-CD1 3.49Å; I35-I272 HydrophobicContact CB-CD1 4.08Å; I35-I272 HydrophobicContact CG1-CD1 4.01Å; I35-I272 HydrophobicContact CG2-CD1 4.16Å
36	S	88.1	Confident	82.6	Confident	71 Å²	71	61.4 Å²	61.4	50%	0.497	33%	0.329	S	S	.	.	H	α-helix	trans	-60.3	-45.8	-178.9	-55	0	0	0	0	111.4	L32 I33 I39 V40	L32-S36 WeakPolarHBondContact O-CB 3.33Å; L32-S36 PolarHBondContact O-N 3.26Å; L32-S36 PolarHBondContact O-OG 3.09Å; I33-S36 PolarHBondContact O-N 3.07Å; S36-I39 PolarHBondContact O-N 3.43Å; S36-V40 WeakPolarHBondContact O-CB 3.49Å; S36-V40 VanDerWaalsContact O-CG2 3.26Å; S36-V40 WeakPolarHBondContact O-CG2 3.41Å; S36-V40 PolarHBondContact O-N 3.22Å
37	L	90.9	Very high	82.9	Confident	57 Å²	57	62.9 Å²	62.9	30%	0.298	33%	0.334	S	S	.	.	H	α-helix	trans	-63.8	-44	178.3	-177.5	64.2	0	0	0	111.4	I33 I35 I39 V40 V41 F55 L265 A269	I33-L37 WeakPolarHBondContact O-CB 3.36Å; I33-L37 PolarHBondContact O-N 2.82Å; I35-L37 VanDerWaalsContact C-N 3.35Å; I35-L37 PolarHBondContact O-N 2.67Å; L37-I39 PolarHBondContact O-N 3.38Å; L37-V40 PolarHBondContact O-N 3.21Å; L37-V41 HydrophobicContact CD1-CG2 4.03Å; L37-V41 HydrophobicContact CG-CG2 4.32Å; L37-V41 WeakPolarHBondContact O-CB 3.44Å; L37-V41 VanDerWaalsContact O-CG2 3.22Å; L37-V41 WeakPolarHBondContact O-CG2 3.48Å; L37-V41 PolarHBondContact O-N 3.36Å; L37-F55 HydrophobicContact CD2-CE2 4.38Å; L37-F55 HydrophobicContact CD2-CZ 3.81Å; L37-F55 HydrophobicContact CG-CZ 4.06Å; L37-L265 HydrophobicContact CD2-CD2 3.94Å; L37-A269 HydrophobicContact CB-CB 4.39Å; L37-A269 HydrophobicContact CD2-CB 4.3Å; L37-A269 HydrophobicContact CG-CB 4.4Å
38	G	86.1	Confident	83.9	Confident	0 Å²	0	66.1 Å²	66.1	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-60.2	-43.6	177	0	0	0	0	0	112.7	G34 I35 R42 I272	G34-G38 PolarHBondContact O-N 3.09Å; I35-G38 PolarHBondContact O-N 3.15Å; G38-R42 VanDerWaalsContact O-CB 3.23Å; G38-R42 WeakPolarHBondContact O-CB 3.05Å; G38-R42 PolarHBondContact O-N 3.46Å; G38-I272 VanDerWaalsContact C-CG2 3.5Å
39	I	86.7	Confident	84.3	Confident	55 Å²	55	70.2 Å²	70.2	28%	0.282	37%	0.372	S	S	.	.	H	α-helix	trans	-65.4	-48.3	177.2	-65.6	169.7	0	0	0	110.6	I35 S36 L37 V41 R42 E43 I272 W278	I35-I39 HydrophobicContact CG2-CD1 3.84Å; I35-I39 WeakPolarHBondContact O-CG1 3.23Å; I35-I39 PolarHBondContact O-N 3.47Å; S36-I39 PolarHBondContact O-N 3.43Å; L37-I39 PolarHBondContact O-N 3.38Å; I39-V41 PolarHBondContact O-N 3.36Å; I39-R42 PolarHBondContact O-N 3.15Å; I39-E43 WeakPolarHBondContact O-CB 3.24Å; I39-E43 PolarHBondContact O-N 2.99Å; I39-I272 HydrophobicContact CG1-CG2 4.12Å; I39-W278 HydrophobicContact CD1-CH2 4.38Å; I39-W278 HydrophobicContact CG1-CH2 4.26Å
40	V	90.9	Very high	84.5	Confident	76 Å²	76	69.5 Å²	69.5	46%	0.461	37%	0.368	S	S	.	.	H	α-helix	trans	-60.7	-46.1	179.3	170.1	0	0	0	0	111	S36 L37 R42 E43 Y44	S36-V40 WeakPolarHBondContact O-CB 3.49Å; S36-V40 VanDerWaalsContact O-CG2 3.26Å; S36-V40 WeakPolarHBondContact O-CG2 3.41Å; S36-V40 PolarHBondContact O-N 3.22Å; L37-V40 PolarHBondContact O-N 3.21Å; V40-R42 VanDerWaalsContact C-N 3.32Å; V40-R42 PolarHBondContact O-N 3.3Å; V40-E43 PolarHBondContact O-N 3.44Å; V40-Y44 HydrophobicContact CG1-CD2 4.04Å; V40-Y44 WeakPolarHBondContact O-CB 3.44Å; V40-Y44 WeakPolarHBondContact O-CD2 3.37Å; V40-Y44 PolarHBondContact O-N 2.68Å
41	V	89.6	Confident	84.9	Confident	23 Å²	23	73.8 Å²	73.8	14%	0.139	39%	0.387	C	S	.	.	H	α-helix	trans	-64.8	-39.5	178.6	174.1	0	0	0	0	110.8	L37 I39 A45 L47 F55 I273	L37-V41 HydrophobicContact CD1-CG2 4.03Å; L37-V41 HydrophobicContact CG-CG2 4.32Å; L37-V41 WeakPolarHBondContact O-CB 3.44Å; L37-V41 VanDerWaalsContact O-CG2 3.22Å; L37-V41 WeakPolarHBondContact O-CG2 3.48Å; L37-V41 PolarHBondContact O-N 3.36Å; I39-V41 PolarHBondContact O-N 3.36Å; V41-A45 HydrophobicContact CG1-CB 4.33Å; V41-A45 CarbonylContact O-C 3.6Å; V41-A45 WeakPolarHBondContact O-CA 3.47Å; V41-A45 WeakPolarHBondContact O-CB 3.45Å; V41-A45 PolarHBondContact O-N 3.09Å; V41-L47 HydrophobicContact CG1-CD1 3.48Å; V41-L47 VanDerWaalsContact CG1-CD1 3.48Å; V41-L47 HydrophobicContact CG1-CG 4.25Å; V41-F55 HydrophobicContact CG2-CE2 4.4Å; V41-F55 HydrophobicContact CG2-CZ 4.4Å; V41-I273 HydrophobicContact CB-CD1 3.78Å; V41-I273 HydrophobicContact CB-CG1 4.09Å; V41-I273 HydrophobicContact CG1-CD1 3.43Å; V41-I273 VanDerWaalsContact CG1-CD1 3.43Å; V41-I273 HydrophobicContact CG1-CG1 3.91Å
42	R	83.8	Confident	85.4	Confident	65 Å²	65	76.1 Å²	76.1	25%	0.245	40%	0.397	C	S	.	.	H	α-helix	trans	-63.4	-40.4	176.8	-179.9	178.5	172.5	-160.4	-0.5	112.8	G38 I39 V40 V275 E276	G38-R42 VanDerWaalsContact O-CB 3.23Å; G38-R42 WeakPolarHBondContact O-CB 3.05Å; G38-R42 PolarHBondContact O-N 3.46Å; I39-R42 PolarHBondContact O-N 3.15Å; V40-R42 VanDerWaalsContact C-N 3.32Å; V40-R42 PolarHBondContact O-N 3.3Å; R42-V275 PolarHBondContact NE-O 3.2Å; R42-V275 PolarHBondContact NH1-O 3.46Å; R42-V275 PolarHBondContact NH2-O 3.24Å; R42-E276 PolarHBondContact NH2-O 2.9Å
43	E	84.9	Confident	85.3	Confident	141 Å²	141	76.4 Å²	76.4	66%	0.659	40%	0.395	S	S	*	.	H	α-helix	trans	-81.1	-36.1	-175.5	-168.2	169.9	-165.9	0	0	112.7	I39 V40	I39-E43 WeakPolarHBondContact O-CB 3.24Å; I39-E43 PolarHBondContact O-N 2.99Å; V40-E43 PolarHBondContact O-N 3.44Å
44	Y	84.9	Confident	85.3	Confident	183 Å²	183	79.8 Å²	79.8	72%	0.718	40%	0.404	S	S	*	.	H	α-helix	trans	-104	-13.6	-173.3	-67.6	-87.5	0	0	0	114.6	V40	V40-Y44 HydrophobicContact CG1-CD2 4.04Å; V40-Y44 WeakPolarHBondContact O-CB 3.44Å; V40-Y44 WeakPolarHBondContact O-CD2 3.37Å; V40-Y44 PolarHBondContact O-N 2.68Å
45	A	80.8	Confident	85.5	Confident	39 Å²	39	81.9 Å²	81.9	32%	0.322	41%	0.414	S	S	.	.			trans	-134.2	120.5	-176.8	0	0	0	0	0	113.5	V41 L47	V41-A45 HydrophobicContact CG1-CB 4.33Å; V41-A45 CarbonylContact O-C 3.6Å; V41-A45 WeakPolarHBondContact O-CA 3.47Å; V41-A45 WeakPolarHBondContact O-CB 3.45Å; V41-A45 PolarHBondContact O-N 3.09Å; A45-L47 HydrophobicContact CB-CG 4.48Å; A45-L47 PolarHBondContact O-N 2.97Å; A45-L47 VanDerWaalsContact O-N 3.15Å
46	T	80	Confident	85.5	Confident	151 Å²	151	79.4 Å²	79.4	93%	0.926	40%	0.404	S	S	*	.			trans	-84	86.4	169.3	53.7	0	0	0	0	110.1
47	L	81.6	Confident	85.5	Confident	52 Å²	52	81.1 Å²	81.1	27%	0.272	40%	0.403	S	S	.	.			trans	-76.6	131.9	176.5	-66.5	174	0	0	0	111.4	V41 A45 H51 K52 I273	V41-L47 HydrophobicContact CG1-CD1 3.48Å; V41-L47 VanDerWaalsContact CG1-CD1 3.48Å; V41-L47 HydrophobicContact CG1-CG 4.25Å; A45-L47 HydrophobicContact CB-CG 4.48Å; A45-L47 PolarHBondContact O-N 2.97Å; A45-L47 VanDerWaalsContact O-N 3.15Å; L47-H51 HydrophobicContact CB-CB 4.35Å; L47-H51 HydrophobicContact CD2-CB 4.05Å; L47-K52 HydrophobicContact CB-CG 3.79Å; L47-K52 VanDerWaalsContact O-CE 3.31Å; L47-K52 WeakPolarHBondContact O-CE 3.42Å; L47-I273 HydrophobicContact CD1-CD1 4.46Å; L47-I273 HydrophobicContact CD1-CG2 4.42Å
48	S	86.2	Confident	85.3	Confident	73 Å²	73	79.4 Å²	79.4	51%	0.51	40%	0.395	S	S	.	.			trans	-63.7	154.1	166.5	172.6	0	0	0	0	110.9	L50 H51 K52	S48-L50 PolarHBondContact O-N 3.03Å; S48-L50 VanDerWaalsContact O-N 3.15Å; S48-H51 PolarHBondContact O-N 3.43Å; S48-K52 PolarHBondContact O-N 3.34Å
49	H	81.9	Confident	84.6	Confident	134 Å²	134	79.5 Å²	79.5	62%	0.62	40%	0.396	S	S	*	.	H	α-helix	trans	-50.1	-41.3	-179	-173.8	-84.6	0	0	0	113	H51 K52 Q53	H49-H51 PolarHBondContact O-N 2.95Å; H49-K52 PolarHBondContact O-N 3.27Å; H49-Q53 PolarHBondContact CE1-NE2 3.44Å; H49-Q53 VanDerWaalsContact CE1-NE2 3.33Å; H49-Q53 PolarHBondContact O-N 3.41Å
50	L	86.8	Confident	84	Confident	80 Å²	80	80.9 Å²	80.9	42%	0.419	40%	0.401	S	S	.	.	H	α-helix	trans	-62.5	-42.7	176.8	-176.5	64.6	0	0	0	112.5	S48 K52 Q53 Y54	S48-L50 PolarHBondContact O-N 3.03Å; S48-L50 VanDerWaalsContact O-N 3.15Å; L50-K52 VanDerWaalsContact C-N 3.35Å; L50-Q53 WeakPolarHBondContact O-CB 3.25Å; L50-Q53 PolarHBondContact O-N 3.34Å; L50-Y54 HydrophobicContact CD1-CE1 4.08Å; L50-Y54 HydrophobicContact CD1-CE2 4.04Å; L50-Y54 HydrophobicContact CD2-CE2 4Å; L50-Y54 HydrophobicContact CG-CD2 4.28Å; L50-Y54 HydrophobicContact CG-CE2 3.66Å; L50-Y54 PolarHBondContact O-N 3Å; L50-Y54 VanDerWaalsContact O-N 3.08Å
51	H	88.2	Confident	83.6	Confident	104 Å²	104	79.7 Å²	79.7	48%	0.481	39%	0.392	S	S	.	.	H	α-helix	trans	-71	-31.5	179.6	-65.7	104.3	0	0	0	112.1	L47 S48 H49 Q53 Y54 F55	L47-H51 HydrophobicContact CB-CB 4.35Å; L47-H51 HydrophobicContact CD2-CB 4.05Å; S48-H51 PolarHBondContact O-N 3.43Å; H49-H51 PolarHBondContact O-N 2.95Å; H51-Q53 VanDerWaalsContact C-N 3.33Å; H51-Y54 PolarHBondContact O-N 3.45Å; H51-F55 WeakPolarHBondContact O-CB 3.21Å; H51-F55 PolarHBondContact O-N 3.35Å
52	K	82	Confident	82.7	Confident	53 Å²	53	78.8 Å²	78.8	23%	0.23	39%	0.386	C	S	.	.	H	α-helix	trans	-61.4	-42.1	171.1	-64.6	-173.9	-179	-165.1	0	111.2	L47 S48 H49 L50 F55 G56 I273	L47-K52 HydrophobicContact CB-CG 3.79Å; L47-K52 VanDerWaalsContact O-CE 3.31Å; L47-K52 WeakPolarHBondContact O-CE 3.42Å; S48-K52 PolarHBondContact O-N 3.34Å; H49-K52 PolarHBondContact O-N 3.27Å; L50-K52 VanDerWaalsContact C-N 3.35Å; K52-F55 PolarHBondContact O-N 2.99Å; K52-G56 PolarHBondContact O-N 2.89Å; K52-G56 VanDerWaalsContact O-N 3.08Å; K52-I273 HydrophobicContact CD-CG2 3.84Å; K52-I273 HydrophobicContact CG-CG2 3.92Å; K52-I273 PolarHBondContact NZ-O 3.38Å
53	Q	80.1	Confident	81.7	Confident	106 Å²	106	77.6 Å²	77.6	50%	0.495	38%	0.384	S	S	.	.	H	α-helix	trans	-63.8	-44.9	175.4	-70.2	-177.8	-25.1	0	0	112.3	H49 L50 H51 F55 G56 F57	H49-Q53 PolarHBondContact CE1-NE2 3.44Å; H49-Q53 VanDerWaalsContact CE1-NE2 3.33Å; H49-Q53 PolarHBondContact O-N 3.41Å; L50-Q53 WeakPolarHBondContact O-CB 3.25Å; L50-Q53 PolarHBondContact O-N 3.34Å; H51-Q53 VanDerWaalsContact C-N 3.33Å; Q53-F55 VanDerWaalsContact C-N 3.31Å; Q53-F55 PolarHBondContact O-N 3.4Å; Q53-G56 PolarHBondContact O-N 3.2Å; Q53-F57 PolarHBondContact O-N 3.03Å
54	Y	91	Very high	81.2	Confident	147 Å²	147	78.2 Å²	78.2	58%	0.576	38%	0.38	S	S	*	.	H	α-helix	trans	-63.3	-37.2	176.1	-65.1	-25.8	0	0	0	112.9	L50 H51 G56 F57	L50-Y54 HydrophobicContact CD1-CE1 4.08Å; L50-Y54 HydrophobicContact CD1-CE2 4.04Å; L50-Y54 HydrophobicContact CD2-CE2 4Å; L50-Y54 HydrophobicContact CG-CD2 4.28Å; L50-Y54 HydrophobicContact CG-CE2 3.66Å; L50-Y54 PolarHBondContact O-N 3Å; L50-Y54 VanDerWaalsContact O-N 3.08Å; H51-Y54 PolarHBondContact O-N 3.45Å; Y54-G56 VanDerWaalsContact C-N 3.34Å; Y54-G56 PolarHBondContact O-N 3.09Å; Y54-F57 WeakPolarHBondContact O-CB 3.3Å; Y54-F57 PolarHBondContact O-N 3.18Å
55	F	88.6	Confident	80.6	Confident	44 Å²	44	72 Å²	72	19%	0.193	36%	0.358	C	S	.	.	H	α-helix	trans	-63.4	-39.2	175.7	-177	-91.5	0	0	0	112.2	L37 V41 H51 K52 Q53 F57 F266 A269 A270 I273	L37-F55 HydrophobicContact CD2-CE2 4.38Å; L37-F55 HydrophobicContact CD2-CZ 3.81Å; L37-F55 HydrophobicContact CG-CZ 4.06Å; V41-F55 HydrophobicContact CG2-CE2 4.4Å; V41-F55 HydrophobicContact CG2-CZ 4.4Å; H51-F55 WeakPolarHBondContact O-CB 3.21Å; H51-F55 PolarHBondContact O-N 3.35Å; K52-F55 PolarHBondContact O-N 2.99Å; Q53-F55 VanDerWaalsContact C-N 3.31Å; Q53-F55 PolarHBondContact O-N 3.4Å; F55-F57 VanDerWaalsContact C-N 3.31Å; F55-F57 PolarHBondContact O-N 3.47Å; F55-F266 HydrophobicContact CE1-CD1 4.39Å; F55-F266 HydrophobicContact CE2-CD1 4.48Å; F55-F266 HydrophobicContact CE2-CE1 4.36Å; F55-F266 HydrophobicContact CZ-CD1 4.27Å; F55-F266 HydrophobicContact CZ-CE1 4.47Å; F55-F266 WeakPolarHBondContact O-CD1 3.49Å; F55-A269 HydrophobicContact CE1-CB 3.53Å; F55-A269 HydrophobicContact CZ-CB 3.87Å; F55-A270 HydrophobicContact CD1-CB 4.04Å; F55-A270 HydrophobicContact CE1-CB 4.49Å; F55-I273 HydrophobicContact CD1-CD1 3.68Å; F55-I273 HydrophobicContact CE1-CD1 3.46Å; F55-I273 VanDerWaalsContact CE1-CD1 3.46Å; F55-I273 HydrophobicContact CG-CD1 4.4Å; F55-I273 HydrophobicContact CZ-CD1 4.03Å
56	G	81.8	Confident	79.7	Confident	13 Å²	13	71 Å²	71	13%	0.134	35%	0.348	C	S	.	.	H	α-helix	trans	-78.6	-4.6	177.7	0	0	0	0	0	115.8	K52 Q53 Y54 G59 E60	K52-G56 PolarHBondContact O-N 2.89Å; K52-G56 VanDerWaalsContact O-N 3.08Å; Q53-G56 PolarHBondContact O-N 3.2Å; Y54-G56 VanDerWaalsContact C-N 3.34Å; Y54-G56 PolarHBondContact O-N 3.09Å; G56-G59 WeakPolarHBondContact O-CA 3.38Å; G56-G59 PolarHBondContact O-N 3.25Å; G56-E60 PolarHBondContact O-N 3.35Å; G56-E60 VanDerWaalsContact O-N 3.08Å
57	F	88.3	Confident	78.8	Confident	107 Å²	107	69.5 Å²	69.5	47%	0.469	33%	0.328	S	S	.	.	H	α-helix	trans	-56.4	-42	-171.9	-178.3	-107.2	0	0	0	114.9	Q53 Y54 F55 G59 E60 I61	Q53-F57 PolarHBondContact O-N 3.03Å; Y54-F57 WeakPolarHBondContact O-CB 3.3Å; Y54-F57 PolarHBondContact O-N 3.18Å; F55-F57 VanDerWaalsContact C-N 3.31Å; F55-F57 PolarHBondContact O-N 3.47Å; F57-G59 PolarHBondContact O-N 2.98Å; F57-E60 WeakPolarHBondContact O-CB 3.43Å; F57-E60 PolarHBondContact O-N 2.85Å; F57-I61 HydrophobicContact CD1-CG1 4.25Å; F57-I61 HydrophobicContact CE1-CD1 4.13Å; F57-I61 HydrophobicContact CE1-CG1 3.81Å; F57-I61 HydrophobicContact CE2-CD1 3.99Å; F57-I61 HydrophobicContact CE2-CG1 4.19Å; F57-I61 HydrophobicContact CZ-CD1 3.62Å; F57-I61 HydrophobicContact CZ-CG1 3.79Å; F57-I61 PolarHBondContact O-N 2.96Å
58	P	86.9	Confident	78.6	Confident	22 Å²	22	73.3 Å²	73.3	14%	0.143	35%	0.348	C	S	.	.	H	α-helix	trans	-60.3	-34.7	174.8	-24.5	35.6	0	0	0	113.3	I61 L62 Y259 F262 F266	P58-I61 PolarHBondContact O-N 3.39Å; P58-L62 PolarHBondContact O-N 2.91Å; P58-Y259 WeakPolarHBondContact CA-OH 3.47Å; P58-Y259 PolarHBondContact O-OH 3Å; P58-F262 HydrophobicContact CB-CD1 4.16Å; P58-F262 HydrophobicContact CB-CE1 3.7Å; P58-F262 HydrophobicContact CB-CZ 4.48Å; P58-F262 HydrophobicContact CG-CE1 4.14Å; P58-F266 HydrophobicContact CB-CB 3.98Å; P58-F266 HydrophobicContact CB-CD2 3.81Å; P58-F266 HydrophobicContact CB-CG 3.99Å; P58-F266 HydrophobicContact CG-CB 4.19Å; P58-F266 HydrophobicContact CG-CD1 4.32Å; P58-F266 HydrophobicContact CG-CD2 3.87Å; P58-F266 HydrophobicContact CG-CE2 4.36Å; P58-F266 HydrophobicContact CG-CG 3.85Å
59	G	71.6	Confident	77.8	Confident	2 Å²	2	70.3 Å²	70.3	2%	0.021	33%	0.326	C	S	.	.	H	α-helix	trans	-66.3	-39.8	172.4	0	0	0	0	0	112.3	G56 F57 L62 M63 G263	G56-G59 WeakPolarHBondContact O-CA 3.38Å; G56-G59 PolarHBondContact O-N 3.25Å; F57-G59 PolarHBondContact O-N 2.98Å; G59-L62 WeakPolarHBondContact O-CB 3.34Å; G59-L62 PolarHBondContact O-N 3.42Å; G59-M63 WeakPolarHBondContact O-CG 3.23Å; G59-M63 PolarHBondContact O-N 2.95Å; G59-M63 VanDerWaalsContact O-N 3.14Å; G59-G263 WeakPolarHBondContact CA-O 3.38Å
60	E	74.3	Confident	77.1	Confident	83 Å²	83	64.9 Å²	64.9	39%	0.388	30%	0.302	S	S	.	.	H	α-helix	trans	-62.2	-43.3	175.1	-167.5	-166.4	149.8	0	0	112	G56 F57 L62 M63 R64	G56-E60 PolarHBondContact O-N 3.35Å; G56-E60 VanDerWaalsContact O-N 3.08Å; F57-E60 WeakPolarHBondContact O-CB 3.43Å; F57-E60 PolarHBondContact O-N 2.85Å; E60-L62 VanDerWaalsContact C-N 3.32Å; E60-L62 PolarHBondContact O-N 3.47Å; E60-M63 PolarHBondContact O-N 3.17Å; E60-M63 VanDerWaalsContact O-N 3.13Å; E60-R64 WeakPolarHBondContact O-CG 3.13Å; E60-R64 PolarHBondContact O-N 3.14Å; E60-R64 IonicContact OE1-CZ 3.88Å; E60-R64 VanDerWaalsContact OE1-CZ 3.23Å; E60-R64 IonicContact OE1-NE 3.8Å; E60-R64 PolarHBondContact OE1-NE 3.12Å; E60-R64 IonicContact OE1-NH2 2.71Å; E60-R64 PolarHBondContact OE1-NH2 3.04Å
61	I	82.3	Confident	76.6	Confident	51 Å²	51	63.3 Å²	63.3	26%	0.262	29%	0.294	S	S	.	.	H	α-helix	trans	-59.8	-43	176.9	-67.4	-59.9	0	0	0	111	F57 P58 M63 R64 M65 Y259	F57-I61 HydrophobicContact CD1-CG1 4.25Å; F57-I61 HydrophobicContact CE1-CD1 4.13Å; F57-I61 HydrophobicContact CE1-CG1 3.81Å; F57-I61 HydrophobicContact CE2-CD1 3.99Å; F57-I61 HydrophobicContact CE2-CG1 4.19Å; F57-I61 HydrophobicContact CZ-CD1 3.62Å; F57-I61 HydrophobicContact CZ-CG1 3.79Å; F57-I61 PolarHBondContact O-N 2.96Å; P58-I61 PolarHBondContact O-N 3.39Å; I61-M63 VanDerWaalsContact C-N 3.32Å; I61-M63 PolarHBondContact O-N 2.85Å; I61-R64 PolarHBondContact O-N 3.35Å; I61-M65 HydrophobicContact CG2-CG 4.35Å; I61-M65 HydrophobicContact CG2-SD 3.8Å; I61-M65 VanDerWaalsContact O-CG 3.31Å; I61-M65 WeakPolarHBondContact O-CG 3.22Å; I61-M65 PolarHBondContact O-N 3.27Å; I61-Y259 HydrophobicContact CB-CE1 4.44Å; I61-Y259 HydrophobicContact CG2-CE1 4.06Å
62	L	71.7	Confident	76.2	Confident	4 Å²	4	60.4 Å²	60.4	2%	0.021	28%	0.284	C	S	.	.	H	α-helix	trans	-56.2	-47.7	174.1	174.3	63.4	0	0	0	111	P58 G59 E60 R64 M65 L66 I256 Y259 M260 I264	P58-L62 PolarHBondContact O-N 2.91Å; G59-L62 WeakPolarHBondContact O-CB 3.34Å; G59-L62 PolarHBondContact O-N 3.42Å; E60-L62 VanDerWaalsContact C-N 3.32Å; E60-L62 PolarHBondContact O-N 3.47Å; L62-R64 VanDerWaalsContact C-N 3.33Å; L62-R64 PolarHBondContact O-N 3Å; L62-M65 PolarHBondContact O-N 3.07Å; L62-L66 HydrophobicContact CD1-CD1 4.26Å; L62-L66 HydrophobicContact CD1-CG 4.3Å; L62-L66 HydrophobicContact CG-CD1 4.22Å; L62-L66 WeakPolarHBondContact O-CG 3.43Å; L62-L66 PolarHBondContact O-N 3.48Å; L62-I256 HydrophobicContact CD1-CG2 4.12Å; L62-Y259 HydrophobicContact CB-CD1 4.12Å; L62-Y259 HydrophobicContact CB-CE1 3.82Å; L62-Y259 HydrophobicContact CD1-CD1 4.07Å; L62-M260 HydrophobicContact CD1-CB 4.3Å; L62-M260 HydrophobicContact CD2-CG 4.45Å; L62-I264 HydrophobicContact CD2-CG1 3.89Å
63	M	62.9	Low	75.7	Confident	40 Å²	40	58 Å²	58	20%	0.197	27%	0.274	C	S	.	.	H	α-helix	trans	-63.6	-36.9	179.6	-65.7	-57.9	-68.8	0	0	112.6	G59 E60 I61 L66 K67 L267 V439	G59-M63 WeakPolarHBondContact O-CG 3.23Å; G59-M63 PolarHBondContact O-N 2.95Å; G59-M63 VanDerWaalsContact O-N 3.14Å; E60-M63 PolarHBondContact O-N 3.17Å; E60-M63 VanDerWaalsContact O-N 3.13Å; I61-M63 VanDerWaalsContact C-N 3.32Å; I61-M63 PolarHBondContact O-N 2.85Å; M63-L66 HydrophobicContact SD-CD1 4.49Å; M63-K67 WeakPolarHBondContact O-CG 3.31Å; M63-K67 PolarHBondContact O-N 3.04Å; M63-L267 HydrophobicContact CG-CD1 3.79Å; M63-L267 HydrophobicContact SD-CD1 3.89Å; M63-V439 HydrophobicContact CE-CG2 4.11Å; M63-V439 HydrophobicContact SD-CG1 4.22Å
64	R	72.9	Confident	75.2	Confident	155 Å²	155	53.3 Å²	53.3	59%	0.585	25%	0.252	S	S	*	.	H	α-helix	trans	-67	-42.5	174.8	-71.1	-179.9	178.5	-129.9	3.9	112	E60 I61 L62 K67 L68	E60-R64 WeakPolarHBondContact O-CG 3.13Å; E60-R64 PolarHBondContact O-N 3.14Å; E60-R64 IonicContact OE1-CZ 3.88Å; E60-R64 VanDerWaalsContact OE1-CZ 3.23Å; E60-R64 IonicContact OE1-NE 3.8Å; E60-R64 PolarHBondContact OE1-NE 3.12Å; E60-R64 IonicContact OE1-NH2 2.71Å; E60-R64 PolarHBondContact OE1-NH2 3.04Å; I61-R64 PolarHBondContact O-N 3.35Å; L62-R64 VanDerWaalsContact C-N 3.33Å; L62-R64 PolarHBondContact O-N 3Å; R64-K67 PolarHBondContact O-N 3.06Å; R64-L68 WeakPolarHBondContact O-CB 3.48Å; R64-L68 PolarHBondContact O-N 3Å
65	M	72.9	Confident	74.7	Confident	51 Å²	51	48.3 Å²	48.3	25%	0.251	24%	0.235	S	C	.	.	H	α-helix	trans	-61.9	-42.7	176.2	-70.1	170.5	72.3	0	0	111.5	I61 L62 L68 V69 I256 Y259	I61-M65 HydrophobicContact CG2-CG 4.35Å; I61-M65 HydrophobicContact CG2-SD 3.8Å; I61-M65 VanDerWaalsContact O-CG 3.31Å; I61-M65 WeakPolarHBondContact O-CG 3.22Å; I61-M65 PolarHBondContact O-N 3.27Å; L62-M65 PolarHBondContact O-N 3.07Å; M65-L68 WeakPolarHBondContact O-CB 3.41Å; M65-L68 PolarHBondContact O-N 3.05Å; M65-V69 PolarHBondContact O-N 2.81Å; M65-I256 HydrophobicContact CB-CD1 4.14Å; M65-I256 HydrophobicContact CB-CG1 4.15Å; M65-I256 HydrophobicContact CB-CG2 4.07Å; M65-I256 HydrophobicContact CE-CB 4.3Å; M65-I256 HydrophobicContact CE-CG1 3.76Å; M65-I256 HydrophobicContact CE-CG2 4.36Å; M65-I256 WeakPolarHBondContact O-CD1 3.43Å; M65-Y259 HydrophobicContact CE-CD1 4.49Å; M65-Y259 HydrophobicContact SD-CD1 3.89Å; M65-Y259 HydrophobicContact SD-CE1 4.22Å; M65-Y259 HydrophobicContact SD-CG 4.41Å
66	L	61	Low	74.2	Confident	20 Å²	20	46.2 Å²	46.2	11%	0.105	23%	0.225	C	C	.	.	H	α-helix	trans	-63.5	-45.1	174.9	-68.6	173.9	0	0	0	111.5	L62 M63 L68 V69 I70 I256 N415	L62-L66 HydrophobicContact CD1-CD1 4.26Å; L62-L66 HydrophobicContact CD1-CG 4.3Å; L62-L66 HydrophobicContact CG-CD1 4.22Å; L62-L66 WeakPolarHBondContact O-CG 3.43Å; L62-L66 PolarHBondContact O-N 3.48Å; M63-L66 HydrophobicContact SD-CD1 4.49Å; L66-L68 VanDerWaalsContact C-N 3.29Å; L66-L68 PolarHBondContact O-N 2.83Å; L66-V69 WeakPolarHBondContact O-CG2 3.33Å; L66-V69 PolarHBondContact O-N 3.49Å; L66-I70 VanDerWaalsContact O-CD1 3.26Å; L66-I70 WeakPolarHBondContact O-CD1 3.48Å; L66-I70 VanDerWaalsContact O-CG1 3.22Å; L66-I70 WeakPolarHBondContact O-CG1 3.35Å; L66-I256 HydrophobicContact CD2-CG2 3.89Å; L66-I256 HydrophobicContact CG-CG2 4.36Å; L66-N415 HydrophobicContact CD1-CB 4.41Å
67	K	61.3	Low	73.7	Confident	119 Å²	119	46 Å²	46	52%	0.517	22%	0.222	S	C	.	.	H	α-helix	trans	-61.5	-35.4	176.6	-75.2	177.3	-179.8	-178	0	113.3	M63 R64 V69 I70	M63-K67 WeakPolarHBondContact O-CG 3.31Å; M63-K67 PolarHBondContact O-N 3.04Å; R64-K67 PolarHBondContact O-N 3.06Å; K67-V69 PolarHBondContact O-N 2.96Å; K67-I70 PolarHBondContact O-N 2.94Å
68	L	77.6	Confident	72.9	Confident	132 Å²	132	41 Å²	41	69%	0.691	20%	0.2	S	C	*	.	H	α-helix	trans	-61.4	-43.2	179.9	174.6	65.5	0	0	0	112.6	R64 M65 L66 I70 P72	R64-L68 WeakPolarHBondContact O-CB 3.48Å; R64-L68 PolarHBondContact O-N 3Å; M65-L68 WeakPolarHBondContact O-CB 3.41Å; M65-L68 PolarHBondContact O-N 3.05Å; L66-L68 VanDerWaalsContact C-N 3.29Å; L66-L68 PolarHBondContact O-N 2.83Å; L68-I70 VanDerWaalsContact C-N 3.31Å; L68-I70 PolarHBondContact O-N 3.44Å; L68-P72 WeakPolarHBondContact O-CD 3.43Å
69	V	69.7	Low	72.6	Confident	9 Å²	9	40 Å²	40	6%	0.055	19%	0.193	C	C	.	.	H	α-helix	trans	-79.6	-12.7	-174	-67.2	0	0	0	0	113.8	M65 L66 K67 P72 L73 T249 L252 V253 I256	M65-V69 PolarHBondContact O-N 2.81Å; L66-V69 WeakPolarHBondContact O-CG2 3.33Å; L66-V69 PolarHBondContact O-N 3.49Å; K67-V69 PolarHBondContact O-N 2.96Å; V69-P72 WeakPolarHBondContact O-CD 3.26Å; V69-P72 WeakPolarHBondContact O-CG 3.3Å; V69-L73 WeakPolarHBondContact O-CB 3.03Å; V69-L73 PolarHBondContact O-N 3.15Å; V69-T249 HydrophobicContact CB-CG2 4.42Å; V69-L252 HydrophobicContact CG1-CB 4.36Å; V69-V253 HydrophobicContact CB-CG2 4.3Å; V69-V253 HydrophobicContact CG2-CG2 4.14Å; V69-I256 HydrophobicContact CB-CD1 4.32Å; V69-I256 HydrophobicContact CG1-CD1 3.39Å; V69-I256 HydrophobicContact CG2-CD1 3.94Å
70	I	67.2	Low	72.7	Confident	21 Å²	21	40.8 Å²	40.8	11%	0.108	20%	0.198	C	C	.	.	H	α-helix	trans	-71.6	-44.1	-171	-75.2	167.7	0	0	0	112.6	L66 K67 L68 L73 I74 V419	L66-I70 VanDerWaalsContact O-CD1 3.26Å; L66-I70 WeakPolarHBondContact O-CD1 3.48Å; L66-I70 VanDerWaalsContact O-CG1 3.22Å; L66-I70 WeakPolarHBondContact O-CG1 3.35Å; K67-I70 PolarHBondContact O-N 2.94Å; L68-I70 VanDerWaalsContact C-N 3.31Å; L68-I70 PolarHBondContact O-N 3.44Å; I70-L73 PolarHBondContact O-N 2.68Å; I70-I74 HydrophobicContact CG2-CD1 3.51Å; I70-I74 HydrophobicContact CG2-CG1 4.12Å; I70-I74 WeakPolarHBondContact O-CB 3.47Å; I70-I74 VanDerWaalsContact O-CG1 3.29Å; I70-I74 WeakPolarHBondContact O-CG1 3.18Å; I70-I74 PolarHBondContact O-N 3.47Å; I70-V419 HydrophobicContact CD1-CB 3.37Å; I70-V419 HydrophobicContact CD1-CG1 3.4Å; I70-V419 VanDerWaalsContact CD1-CG1 3.4Å; I70-V419 HydrophobicContact CD1-CG2 3.12Å; I70-V419 HydrophobicContact CG2-CG1 4.29Å
71	L	76.9	Confident	72.4	Confident	47 Å²	47	37.3 Å²	37.3	25%	0.246	19%	0.185	C	C	.	.	H	α-helix	trans	-58.3	-55.2	179.6	179.7	64.4	0	0	0	112.9	L73 I75 C161 L217	L71-L73 VanDerWaalsContact C-N 3.28Å; L71-L73 PolarHBondContact O-N 3.32Å; L71-I75 HydrophobicContact CD1-CD1 3.72Å; L71-I75 HydrophobicContact CD1-CG1 4.42Å; L71-I75 HydrophobicContact CG-CD1 4.14Å; L71-I75 WeakPolarHBondContact O-CG1 3.41Å; L71-I75 PolarHBondContact O-N 3.16Å; L71-C161 HydrophobicContact CD1-CB 4.22Å; L71-C161 HydrophobicContact CD2-CB 3.83Å; L71-L217 HydrophobicContact CD1-CD1 3.49Å; L71-L217 VanDerWaalsContact CD1-CD1 3.49Å
72	P	80.1	Confident	71.8	Confident	43 Å²	43	35.2 Å²	35.2	28%	0.279	17%	0.174	S	C	.	.	H	α-helix	trans	-65.2	-33.5	179.2	24.7	-33.6	0	0	0	112.3	L68 V69 S76 T249	L68-P72 WeakPolarHBondContact O-CD 3.43Å; V69-P72 WeakPolarHBondContact O-CD 3.26Å; V69-P72 WeakPolarHBondContact O-CG 3.3Å; P72-S76 VanDerWaalsContact O-CB 3.28Å; P72-S76 WeakPolarHBondContact O-CB 3.4Å; P72-S76 PolarHBondContact O-N 3.1Å; P72-S76 PolarHBondContact O-OG 3.34Å; P72-T249 HydrophobicContact CB-CG2 4.4Å; P72-T249 HydrophobicContact CG-CG2 4.09Å
73	L	70.6	Confident	71.8	Confident	3 Å²	3	35.3 Å²	35.3	2%	0.016	18%	0.176	C	C	.	.	H	α-helix	trans	-68.2	-48	180	-172.5	64.4	0	0	0	112	V69 I70 L71 I75 S76 S77 N246 T249 M250 A411 V413	V69-L73 WeakPolarHBondContact O-CB 3.03Å; V69-L73 PolarHBondContact O-N 3.15Å; I70-L73 PolarHBondContact O-N 2.68Å; L71-L73 VanDerWaalsContact C-N 3.28Å; L71-L73 PolarHBondContact O-N 3.32Å; L73-I75 PolarHBondContact O-N 3.48Å; L73-S76 PolarHBondContact O-OG 3.08Å; L73-S77 WeakPolarHBondContact O-CB 3.45Å; L73-S77 PolarHBondContact O-N 2.9Å; L73-S77 PolarHBondContact O-OG 3.5Å; L73-N246 WeakPolarHBondContact CD1-OD1 2.92Å; L73-T249 HydrophobicContact CB-CG2 3.96Å; L73-T249 HydrophobicContact CD1-CG2 4.21Å; L73-M250 HydrophobicContact CD1-CG 4.41Å; L73-M250 HydrophobicContact CD1-SD 3.97Å; L73-A411 HydrophobicContact CD1-CB 4.4Å; L73-A411 HydrophobicContact CD2-CB 3.24Å; L73-A411 HydrophobicContact CG-CB 3.53Å; L73-V413 HydrophobicContact CD2-CB 4.4Å; L73-V413 HydrophobicContact CD2-CG1 3.8Å; L73-V413 HydrophobicContact CD2-CG2 3.7Å
74	I	69.7	Low	71.9	Confident	7 Å²	7	36.4 Å²	36.4	4%	0.036	19%	0.191	C	C	.	.	H	α-helix	trans	-59.3	-48.7	178.1	-69.8	178.8	0	0	0	110.3	I70 M78 V214 I218 G409	I70-I74 HydrophobicContact CG2-CD1 3.51Å; I70-I74 HydrophobicContact CG2-CG1 4.12Å; I70-I74 WeakPolarHBondContact O-CB 3.47Å; I70-I74 VanDerWaalsContact O-CG1 3.29Å; I70-I74 WeakPolarHBondContact O-CG1 3.18Å; I70-I74 PolarHBondContact O-N 3.47Å; I74-M78 HydrophobicContact CG2-CG 4.25Å; I74-M78 WeakPolarHBondContact O-CB 3.31Å; I74-M78 WeakPolarHBondContact O-CG 3.15Å; I74-M78 PolarHBondContact O-N 2.94Å; I74-V214 HydrophobicContact CD1-CG1 3.65Å; I74-V214 HydrophobicContact CD1-CG2 4.41Å; I74-I218 HydrophobicContact CG2-CG1 4.09Å; I74-G409 WeakPolarHBondContact CG1-O 3.44Å
75	I	80.9	Confident	71.3	Confident	41 Å²	41	30.3 Å²	30.3	21%	0.21	17%	0.17	C	C	.	.	H	α-helix	trans	-62.5	-52.9	-177.3	-66	171	0	0	0	110.6	L71 L73 I79 F242	L71-I75 HydrophobicContact CD1-CD1 3.72Å; L71-I75 HydrophobicContact CD1-CG1 4.42Å; L71-I75 HydrophobicContact CG-CD1 4.14Å; L71-I75 WeakPolarHBondContact O-CG1 3.41Å; L71-I75 PolarHBondContact O-N 3.16Å; L73-I75 PolarHBondContact O-N 3.48Å; I75-I79 HydrophobicContact CG2-CD1 3.71Å; I75-I79 WeakPolarHBondContact O-CB 3.22Å; I75-I79 WeakPolarHBondContact O-CD1 3.23Å; I75-I79 WeakPolarHBondContact O-CG1 3.42Å; I75-I79 PolarHBondContact O-N 3.26Å; I75-F242 HydrophobicContact CG2-CD1 4.47Å; I75-F242 HydrophobicContact CG2-CE1 3.89Å
76	S	78.1	Confident	70.4	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-67.4	-46.8	-176.1	59.3	0	0	0	0	112.8	P72 L73 T80 F242 N246	P72-S76 VanDerWaalsContact O-CB 3.28Å; P72-S76 WeakPolarHBondContact O-CB 3.4Å; P72-S76 PolarHBondContact O-N 3.1Å; P72-S76 PolarHBondContact O-OG 3.34Å; L73-S76 PolarHBondContact O-OG 3.08Å; S76-T80 WeakPolarHBondContact O-CG2 3.07Å; S76-T80 PolarHBondContact O-N 3.15Å; S76-T80 PolarHBondContact O-OG1 3.44Å; S76-F242 WeakPolarHBondContact CB-O 3.49Å; S76-N246 WeakPolarHBondContact OG-CA 3.27Å
77	S	70.9	Confident	70.2	Confident	8 Å²	8	33.6 Å²	33.6	6%	0.056	19%	0.194	C	C	.	.	H	α-helix	trans	-65.5	-38.9	179.5	-72.7	0	0	0	0	113.2	L73 T80 G81 N246	L73-S77 WeakPolarHBondContact O-CB 3.45Å; L73-S77 PolarHBondContact O-N 2.9Å; L73-S77 PolarHBondContact O-OG 3.5Å; S77-T80 PolarHBondContact O-OG1 3.34Å; S77-G81 PolarHBondContact O-N 3.41Å; S77-N246 PolarHBondContact OG-OD1 3.34Å
78	M	71.2	Confident	69.7	Low	3 Å²	3	37.7 Å²	37.7	2%	0.015	22%	0.215	C	C	.	.	H	α-helix	trans	-72.2	-42.4	-179	-71.8	-64.2	109.2	0	0	111.9	I74 V82 C221 I408	I74-M78 HydrophobicContact CG2-CG 4.25Å; I74-M78 WeakPolarHBondContact O-CB 3.31Å; I74-M78 WeakPolarHBondContact O-CG 3.15Å; I74-M78 PolarHBondContact O-N 2.94Å; M78-V82 WeakPolarHBondContact O-CB 3.5Å; M78-V82 WeakPolarHBondContact O-CG2 3.46Å; M78-V82 PolarHBondContact O-N 2.82Å; M78-C221 HydrophobicContact CB-CB 3.75Å; M78-I408 VanDerWaalsContact CE-O 3.27Å; M78-I408 WeakPolarHBondContact CE-O 3.47Å; M78-I408 HydrophobicContact SD-CG2 4.3Å
79	I	80.3	Confident	68.5	Low	1 Å²	1	34.8 Å²	34.8	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-62.9	-48.9	179.5	-68.7	167.7	0	0	0	110.3	I75 A83 C221 F224 I228 F242	I75-I79 HydrophobicContact CG2-CD1 3.71Å; I75-I79 WeakPolarHBondContact O-CB 3.22Å; I75-I79 WeakPolarHBondContact O-CD1 3.23Å; I75-I79 WeakPolarHBondContact O-CG1 3.42Å; I75-I79 PolarHBondContact O-N 3.26Å; I79-A83 WeakPolarHBondContact O-CB 3.33Å; I79-A83 PolarHBondContact O-N 3.48Å; I79-C221 HydrophobicContact CG1-CB 3.85Å; I79-F224 HydrophobicContact CD1-CD1 3.73Å; I79-F224 HydrophobicContact CD1-CE1 4.2Å; I79-F224 HydrophobicContact CG1-CD1 4.12Å; I79-F224 HydrophobicContact CG2-CD1 4.42Å; I79-I228 HydrophobicContact CG2-CD1 3.98Å; I79-F242 HydrophobicContact CB-CD2 4.4Å; I79-F242 HydrophobicContact CB-CG 4.33Å; I79-F242 HydrophobicContact CD1-CD1 3.95Å; I79-F242 HydrophobicContact CD1-CD2 4.16Å; I79-F242 HydrophobicContact CD1-CE1 3.61Å; I79-F242 HydrophobicContact CD1-CE2 3.87Å; I79-F242 HydrophobicContact CD1-CG 4.23Å; I79-F242 HydrophobicContact CD1-CZ 3.57Å; I79-F242 HydrophobicContact CG2-CB 4.38Å; I79-F242 HydrophobicContact CG2-CD2 3.69Å; I79-F242 HydrophobicContact CG2-CE2 4.18Å; I79-F242 HydrophobicContact CG2-CG 4.05Å
80	T	74.1	Confident	68	Low	18 Å²	18	35 Å²	35	11%	0.11	20%	0.204	C	C	.	.	H	α-helix	trans	-68.1	-40.9	-179.7	55.8	0	0	0	0	112.1	S76 S77 V82 A84 F242 D243	S76-T80 WeakPolarHBondContact O-CG2 3.07Å; S76-T80 PolarHBondContact O-N 3.15Å; S76-T80 PolarHBondContact O-OG1 3.44Å; S77-T80 PolarHBondContact O-OG1 3.34Å; T80-V82 VanDerWaalsContact C-N 3.35Å; T80-V82 PolarHBondContact O-N 2.93Å; T80-A84 WeakPolarHBondContact O-CB 3.28Å; T80-A84 PolarHBondContact O-N 3.44Å; T80-A84 VanDerWaalsContact O-N 3.16Å; T80-F242 HydrophobicContact CG2-CB 3.67Å; T80-D243 HydrophobicContact CG2-CB 4Å
81	G	67.6	Low	68.1	Low	11 Å²	11	35.7 Å²	35.7	11%	0.113	22%	0.216	C	C	.	.	H	α-helix	trans	-61	-41	179.1	0	0	0	0	0	113.1	S77	S77-G81 PolarHBondContact O-N 3.41Å
82	V	70.1	Confident	68.2	Low	6 Å²	6	39.7 Å²	39.7	4%	0.036	23%	0.232	C	C	.	.	H	α-helix	trans	-82.5	-37	-179	176.2	0	0	0	0	112.4	M78 T80 A84 L85 V222 L226	M78-V82 WeakPolarHBondContact O-CB 3.5Å; M78-V82 WeakPolarHBondContact O-CG2 3.46Å; M78-V82 PolarHBondContact O-N 2.82Å; T80-V82 VanDerWaalsContact C-N 3.35Å; T80-V82 PolarHBondContact O-N 2.93Å; V82-A84 PolarHBondContact O-N 3.49Å; V82-L85 HydrophobicContact CB-CD1 4.5Å; V82-L85 HydrophobicContact CG1-CD1 4.28Å; V82-L85 VanDerWaalsContact O-CB 3.24Å; V82-L85 WeakPolarHBondContact O-CB 3.33Å; V82-L85 VanDerWaalsContact O-CG 3.3Å; V82-L85 WeakPolarHBondContact O-CG 3.38Å; V82-L85 PolarHBondContact O-N 3.11Å; V82-L85 VanDerWaalsContact O-N 3.08Å; V82-V222 HydrophobicContact CG1-CG1 4.28Å; V82-V222 HydrophobicContact CG2-CB 4.45Å; V82-V222 HydrophobicContact CG2-CG1 4.33Å; V82-V222 HydrophobicContact CG2-CG2 4.13Å; V82-L226 HydrophobicContact CG1-CB 4.43Å; V82-L226 HydrophobicContact CG1-CD1 4.49Å; V82-L226 HydrophobicContact CG1-CD2 3.46Å; V82-L226 VanDerWaalsContact CG1-CD2 3.46Å; V82-L226 HydrophobicContact CG1-CG 3.46Å; V82-L226 VanDerWaalsContact CG1-CG 3.46Å
83	A	72.5	Confident	68.2	Low	7 Å²	7	38 Å²	38	6%	0.058	22%	0.221	C	C	.	.	H	α-helix	trans	-65.9	-27.9	178.3	0	0	0	0	0	112.8	I79 L85 G225 L239	I79-A83 WeakPolarHBondContact O-CB 3.33Å; I79-A83 PolarHBondContact O-N 3.48Å; A83-L85 PolarHBondContact O-N 3.24Å; A83-G225 WeakPolarHBondContact CA-O 3.4Å; A83-G225 VanDerWaalsContact CB-O 3.27Å; A83-G225 WeakPolarHBondContact CB-O 3.43Å; A83-L239 HydrophobicContact CB-CD1 3.39Å
84	A	63.6	Low	68.5	Low	62 Å²	62	38.2 Å²	38.2	51%	0.512	22%	0.223	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.5	-11.9	173.1	0	0	0	0	0	114	T80 V82 D86 F359	T80-A84 WeakPolarHBondContact O-CB 3.28Å; T80-A84 PolarHBondContact O-N 3.44Å; T80-A84 VanDerWaalsContact O-N 3.16Å; V82-A84 PolarHBondContact O-N 3.49Å; A84-D86 PolarHBondContact O-N 3.31Å; A84-F359 WeakPolarHBondContact O-CE2 3.48Å
85	L	60.4	Low	69.2	Low	28 Å²	28	42.9 Å²	42.9	15%	0.147	25%	0.247	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-18.1	-174.3	-59.1	175	0	0	0	114.4	V82 A83 S87 S90 F359 V363	V82-L85 HydrophobicContact CB-CD1 4.5Å; V82-L85 HydrophobicContact CG1-CD1 4.28Å; V82-L85 VanDerWaalsContact O-CB 3.24Å; V82-L85 WeakPolarHBondContact O-CB 3.33Å; V82-L85 VanDerWaalsContact O-CG 3.3Å; V82-L85 WeakPolarHBondContact O-CG 3.38Å; V82-L85 PolarHBondContact O-N 3.11Å; V82-L85 VanDerWaalsContact O-N 3.08Å; A83-L85 PolarHBondContact O-N 3.24Å; L85-S87 PolarHBondContact O-N 3.23Å; L85-S90 PolarHBondContact O-OG 3.14Å; L85-F359 HydrophobicContact CB-CE2 4.47Å; L85-F359 HydrophobicContact CB-CZ 4.09Å; L85-F359 HydrophobicContact CD2-CE1 3.64Å; L85-F359 HydrophobicContact CD2-CE2 3.88Å; L85-F359 HydrophobicContact CD2-CZ 3.15Å; L85-F359 HydrophobicContact CG-CZ 4.18Å; L85-V363 HydrophobicContact CD2-CB 4.36Å; L85-V363 HydrophobicContact CD2-CG1 3.86Å; L85-V363 HydrophobicContact CD2-CG2 3.61Å
86	D	55.2	Low	69.6	Low	73 Å²	73	44.2 Å²	44.2	39%	0.39	25%	0.25	S	C	.	.			trans	-102.6	83.1	-163.4	-161.1	33.2	0	0	0	114.3	A84 K230	A84-D86 PolarHBondContact O-N 3.31Å; D86-K230 WeakPolarHBondContact OD2-CG 3.19Å
87	S	55.9	Low	70.1	Confident	67 Å²	67	44.3 Å²	44.3	47%	0.469	25%	0.25	S	S	.	.			trans	-129.4	146.8	154.4	81.7	0	0	0	0	109.3	L85 V89 S90 G91	L85-S87 PolarHBondContact O-N 3.23Å; S87-V89 PolarHBondContact O-N 3.2Å; S87-S90 CarbonylContact O-C 2.97Å; S87-S90 VanDerWaalsContact O-CA 3.28Å; S87-S90 WeakPolarHBondContact O-CA 3.39Å; S87-S90 VanDerWaalsContact O-CB 3.25Å; S87-S90 WeakPolarHBondContact O-CB 3.34Å; S87-S90 PolarHBondContact O-N 3.32Å; S87-S90 WeakPolarHBondContact OG-CB 3.23Å; S87-S90 PolarHBondContact OG-N 2.94Å; S87-G91 PolarHBondContact O-N 2.97Å
88	E	52.2	Low	70.8	Confident	204 Å²	204	45.7 Å²	45.7	95%	0.953	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-27.1	-170.4	-79.9	-176.8	137.9	0	0	114.6
89	V	50.7	Low	71.7	Confident	71 Å²	71	50.2 Å²	50.2	43%	0.43	28%	0.282	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.4	-26.8	173.6	-174.8	0	0	0	0	111.8	S87 M475	S87-V89 PolarHBondContact O-N 3.2Å; V89-M475 HydrophobicContact CG1-CE 3.85Å; V89-M475 HydrophobicContact CG1-CG 3.84Å; V89-M475 HydrophobicContact CG1-SD 3.6Å
90	S	59.7	Low	72.4	Confident	14 Å²	14	50.9 Å²	50.9	10%	0.098	28%	0.284	C	S	.	.	H	α-helix	trans	-72.6	-28.8	174.2	179.3	0	0	0	0	113.4	L85 S87 K92 I93 G94 F359	L85-S90 PolarHBondContact O-OG 3.14Å; S87-S90 CarbonylContact O-C 2.97Å; S87-S90 VanDerWaalsContact O-CA 3.28Å; S87-S90 WeakPolarHBondContact O-CA 3.39Å; S87-S90 VanDerWaalsContact O-CB 3.25Å; S87-S90 WeakPolarHBondContact O-CB 3.34Å; S87-S90 PolarHBondContact O-N 3.32Å; S87-S90 WeakPolarHBondContact OG-CB 3.23Å; S87-S90 PolarHBondContact OG-N 2.94Å; S90-K92 VanDerWaalsContact C-N 3.35Å; S90-K92 PolarHBondContact O-N 2.79Å; S90-I93 PolarHBondContact O-N 3.48Å; S90-I93 VanDerWaalsContact O-N 3.13Å; S90-G94 PolarHBondContact O-N 3.31Å; S90-F359 WeakPolarHBondContact OG-CD2 3.28Å; S90-F359 WeakPolarHBondContact OG-CE2 3.38Å; S90-F359 WeakPolarHBondContact OG-CZ 3.31Å
91	G	68.8	Low	73.3	Confident	35 Å²	35	50.1 Å²	50.1	36%	0.361	28%	0.279	S	S	.	.	H	α-helix	trans	-57.2	-40.7	-174.4	0	0	0	0	0	114.5	S87 L95	S87-G91 PolarHBondContact O-N 2.97Å; G91-L95 WeakPolarHBondContact O-CB 3.44Å; G91-L95 PolarHBondContact O-N 3.25Å
92	K	79.5	Confident	74.4	Confident	131 Å²	131	53.7 Å²	53.7	57%	0.57	29%	0.292	S	S	*	.	H	α-helix	trans	-73.6	-39.7	177.3	-71	-179.9	-178.2	172.9	0	112.8	S90 G94 R96	S90-K92 VanDerWaalsContact C-N 3.35Å; S90-K92 PolarHBondContact O-N 2.79Å; K92-G94 VanDerWaalsContact C-N 3.34Å; K92-R96 VanDerWaalsContact O-CG 3.29Å; K92-R96 WeakPolarHBondContact O-CG 2.84Å; K92-R96 PolarHBondContact O-N 3.17Å; K92-R96 VanDerWaalsContact O-N 3.16Å
93	I	80.9	Confident	75.5	Confident	9 Å²	9	56.1 Å²	56.1	5%	0.046	31%	0.309	C	S	.	.	H	α-helix	trans	-64	-45.6	177.5	-64.7	175.7	0	0	0	109	S90 R96 A97 I356 F359 V464	S90-I93 PolarHBondContact O-N 3.48Å; S90-I93 VanDerWaalsContact O-N 3.13Å; I93-R96 PolarHBondContact O-N 3.18Å; I93-A97 PolarHBondContact O-N 3.36Å; I93-A97 VanDerWaalsContact O-N 3.11Å; I93-I356 HydrophobicContact CD1-CD1 3.91Å; I93-I356 HydrophobicContact CG1-CD1 4.37Å; I93-I356 HydrophobicContact CG2-CD1 3.67Å; I93-F359 HydrophobicContact CG2-CD1 4.43Å; I93-V464 HydrophobicContact CG2-CG1 3.64Å
94	G	77.3	Confident	76.7	Confident	6 Å²	6	55.8 Å²	55.8	6%	0.062	31%	0.306	C	S	.	.	H	α-helix	trans	-69.5	-39.9	178	0	0	0	0	0	114.1	S90 K92 R96 A97 V98	S90-G94 PolarHBondContact O-N 3.31Å; K92-G94 VanDerWaalsContact C-N 3.34Å; G94-R96 VanDerWaalsContact C-N 3.28Å; G94-R96 PolarHBondContact O-N 2.9Å; G94-A97 WeakPolarHBondContact O-CB 3.43Å; G94-A97 PolarHBondContact O-N 3.21Å; G94-A97 VanDerWaalsContact O-N 3.12Å; G94-V98 WeakPolarHBondContact O-CG2 3.42Å; G94-V98 PolarHBondContact O-N 3.47Å
95	L	83.8	Confident	78.1	Confident	106 Å²	106	53 Å²	53	56%	0.555	28%	0.283	S	S	*	.	H	α-helix	trans	-59.1	-41.6	173.7	-178.7	62.6	0	0	0	111.6	G91 V98 I99	G91-L95 WeakPolarHBondContact O-CB 3.44Å; G91-L95 PolarHBondContact O-N 3.25Å; L95-V98 PolarHBondContact O-N 2.9Å; L95-I99 HydrophobicContact CD1-CD1 4.09Å; L95-I99 HydrophobicContact CD1-CG1 4.32Å; L95-I99 HydrophobicContact CG-CD1 3.92Å; L95-I99 WeakPolarHBondContact O-CB 3.45Å; L95-I99 VanDerWaalsContact O-CG1 3.25Å; L95-I99 WeakPolarHBondContact O-CG1 3.4Å; L95-I99 PolarHBondContact O-N 3.22Å
96	R	89.8	Confident	79.8	Confident	69 Å²	69	55 Å²	55	26%	0.26	29%	0.293	S	S	.	.	H	α-helix	trans	-63.4	-40.9	175.4	-71.4	167.4	178.6	155.9	5.7	112	K92 I93 G94 Y100 V464 L467 S468 E471	K92-R96 VanDerWaalsContact O-CG 3.29Å; K92-R96 WeakPolarHBondContact O-CG 2.84Å; K92-R96 PolarHBondContact O-N 3.17Å; K92-R96 VanDerWaalsContact O-N 3.16Å; I93-R96 PolarHBondContact O-N 3.18Å; G94-R96 VanDerWaalsContact C-N 3.28Å; G94-R96 PolarHBondContact O-N 2.9Å; R96-Y100 WeakPolarHBondContact O-CB 3.5Å; R96-Y100 PolarHBondContact O-N 3.1Å; R96-V464 HydrophobicContact CB-CG2 4.4Å; R96-L467 PolarHBondContact NH1-O 2.83Å; R96-S468 PolarHBondContact NH1-OG 3.49Å; R96-E471 IonicContact CZ-OE1 3.23Å; R96-E471 IonicContact NH1-OE1 2.88Å; R96-E471 PolarHBondContact NH1-OE1 3.09Å; R96-E471 IonicContact NH1-OE2 3.05Å; R96-E471 PolarHBondContact NH1-OE2 3.2Å; R96-E471 VanDerWaalsContact NH1-OE2 3.12Å; R96-E471 IonicContact NH2-OE1 2.75Å; R96-E471 PolarHBondContact NH2-OE1 3.39Å; R96-E471 IonicContact NH2-OE2 2.74Å
97	A	87.6	Confident	81.8	Confident	1 Å²	1	54.7 Å²	54.7	1%	0.008	29%	0.291	C	S	.	.	H	α-helix	trans	-63.6	-48	176.5	0	0	0	0	0	111.6	I93 G94 I99 Y100 Y101 V360 V464	I93-A97 PolarHBondContact O-N 3.36Å; I93-A97 VanDerWaalsContact O-N 3.11Å; G94-A97 WeakPolarHBondContact O-CB 3.43Å; G94-A97 PolarHBondContact O-N 3.21Å; G94-A97 VanDerWaalsContact O-N 3.12Å; A97-I99 PolarHBondContact O-N 2.96Å; A97-Y100 WeakPolarHBondContact O-CB 3.47Å; A97-Y100 PolarHBondContact O-N 3.36Å; A97-Y101 HydrophobicContact CB-CE2 4.26Å; A97-Y101 WeakPolarHBondContact O-CD2 2.94Å; A97-Y101 PolarHBondContact O-N 3.03Å; A97-V360 HydrophobicContact CB-CG1 4.48Å; A97-V360 HydrophobicContact CB-CG2 4.25Å; A97-V464 HydrophobicContact CB-CG2 4Å
98	V	85.2	Confident	83.7	Confident	38 Å²	38	51.5 Å²	51.5	23%	0.23	27%	0.269	C	S	.	.	H	α-helix	trans	-60.9	-46.5	178.6	172.5	0	0	0	0	111.3	G94 L95 Y100 Y101 F102	G94-V98 WeakPolarHBondContact O-CG2 3.42Å; G94-V98 PolarHBondContact O-N 3.47Å; L95-V98 PolarHBondContact O-N 2.9Å; V98-Y100 VanDerWaalsContact C-N 3.29Å; V98-Y100 PolarHBondContact O-N 3.38Å; V98-Y101 PolarHBondContact O-N 2.98Å; V98-F102 HydrophobicContact CG1-CD2 3.65Å; V98-F102 HydrophobicContact CG1-CE2 3.69Å; V98-F102 WeakPolarHBondContact O-CD2 3.17Å; V98-F102 PolarHBondContact O-N 3.5Å
99	I	91.4	Very high	85.9	Confident	97 Å²	97	41.8 Å²	41.8	50%	0.497	22%	0.223	S	C	.	.	H	α-helix	trans	-58.6	-43.4	176.3	-70.8	168.1	0	0	0	110.9	L95 A97 S103	L95-I99 HydrophobicContact CD1-CD1 4.09Å; L95-I99 HydrophobicContact CD1-CG1 4.32Å; L95-I99 HydrophobicContact CG-CD1 3.92Å; L95-I99 WeakPolarHBondContact O-CB 3.45Å; L95-I99 VanDerWaalsContact O-CG1 3.25Å; L95-I99 WeakPolarHBondContact O-CG1 3.4Å; L95-I99 PolarHBondContact O-N 3.22Å; A97-I99 PolarHBondContact O-N 2.96Å; I99-S103 VanDerWaalsContact O-CB 3.32Å; I99-S103 WeakPolarHBondContact O-CB 3.41Å; I99-S103 PolarHBondContact O-N 2.99Å; I99-S103 VanDerWaalsContact O-N 3.1Å; I99-S103 PolarHBondContact O-OG 2.79Å
100	Y	94.9	Very high	88	Confident	15 Å²	15	42.3 Å²	42.3	6%	0.059	22%	0.223	C	C	.	.	H	α-helix	trans	-60.6	-50.3	176.6	166.8	-97.4	0	0	0	111.4	R96 A97 V98 F102 S103 T104 I306 G456 Y459 G460 I463	R96-Y100 WeakPolarHBondContact O-CB 3.5Å; R96-Y100 PolarHBondContact O-N 3.1Å; A97-Y100 WeakPolarHBondContact O-CB 3.47Å; A97-Y100 PolarHBondContact O-N 3.36Å; V98-Y100 VanDerWaalsContact C-N 3.29Å; V98-Y100 PolarHBondContact O-N 3.38Å; Y100-F102 PolarHBondContact O-N 3.37Å; Y100-S103 WeakPolarHBondContact O-CB 3.48Å; Y100-S103 PolarHBondContact O-N 2.87Å; Y100-S103 VanDerWaalsContact O-N 3.12Å; Y100-T104 HydrophobicContact CD2-CG2 3.94Å; Y100-T104 HydrophobicContact CE1-CG2 4.22Å; Y100-T104 HydrophobicContact CE2-CG2 3.44Å; Y100-T104 VanDerWaalsContact CE2-CG2 3.44Å; Y100-T104 PolarHBondContact O-N 2.85Å; Y100-T104 PolarHBondContact O-OG1 3.36Å; Y100-I306 HydrophobicContact CE2-CG2 4.25Å; Y100-G456 WeakPolarHBondContact CE1-O 3.43Å; Y100-G456 PolarHBondContact OH-O 3.31Å; Y100-Y459 WeakPolarHBondContact OH-CB 3.42Å; Y100-G460 PolarHBondContact OH-N 3.38Å; Y100-I463 HydrophobicContact CD2-CD1 3.81Å; Y100-I463 HydrophobicContact CE2-CD1 3.33Å
101	Y	91.8	Very high	89.9	Confident	2 Å²	2	43 Å²	43	1%	0.008	23%	0.225	C	C	.	.	H	α-helix	trans	-59.8	-47.1	-178.6	-62.8	-27.2	0	0	0	113.3	A97 V98 S103 T104 T105 V360 V363 G364 I367 N368	A97-Y101 HydrophobicContact CB-CE2 4.26Å; A97-Y101 WeakPolarHBondContact O-CD2 2.94Å; A97-Y101 PolarHBondContact O-N 3.03Å; V98-Y101 PolarHBondContact O-N 2.98Å; Y101-S103 VanDerWaalsContact C-N 3.28Å; Y101-S103 PolarHBondContact O-N 3.25Å; Y101-T104 PolarHBondContact O-N 3.38Å; Y101-T104 PolarHBondContact O-OG1 3.44Å; Y101-T104 VanDerWaalsContact O-OG1 3.11Å; Y101-T105 VanDerWaalsContact O-CB 3.3Å; Y101-T105 WeakPolarHBondContact O-CB 3.35Å; Y101-T105 PolarHBondContact O-N 3.37Å; Y101-T105 PolarHBondContact O-OG1 3.49Å; Y101-V360 WeakPolarHBondContact OH-CG1 3.25Å; Y101-V360 PolarHBondContact OH-O 3.11Å; Y101-V363 HydrophobicContact CE2-CG1 4.15Å; Y101-G364 VanDerWaalsContact OH-CA 3.31Å; Y101-G364 WeakPolarHBondContact OH-CA 3.34Å; Y101-I367 HydrophobicContact CD2-CG2 4.4Å; Y101-N368 WeakPolarHBondContact CA-OD1 3.42Å; Y101-N368 HydrophobicContact CD1-CB 3.37Å; Y101-N368 WeakPolarHBondContact CD1-OD1 3.45Å; Y101-N368 HydrophobicContact CD2-CB 4Å; Y101-N368 HydrophobicContact CE1-CB 3.71Å; Y101-N368 HydrophobicContact CE2-CB 4.28Å; Y101-N368 HydrophobicContact CG-CB 3.53Å
102	F	90.9	Very high	91.2	Very high	86 Å²	86	41.3 Å²	41.3	38%	0.377	21%	0.208	S	C	.	.	H	α-helix	trans	-62.4	-39.3	176.1	-85.7	-76.3	0	0	0	111.6	V98 Y100 I106 T404 I408	V98-F102 HydrophobicContact CG1-CD2 3.65Å; V98-F102 HydrophobicContact CG1-CE2 3.69Å; V98-F102 WeakPolarHBondContact O-CD2 3.17Å; V98-F102 PolarHBondContact O-N 3.5Å; Y100-F102 PolarHBondContact O-N 3.37Å; F102-I106 WeakPolarHBondContact O-CB 3.28Å; F102-I106 WeakPolarHBondContact O-CD1 3.4Å; F102-I106 WeakPolarHBondContact O-CG1 3.49Å; F102-I106 PolarHBondContact O-N 3.33Å; F102-T404 HydrophobicContact CD1-CG2 4.46Å; F102-I408 HydrophobicContact CD1-CD1 4.34Å; F102-I408 HydrophobicContact CE1-CD1 3.43Å; F102-I408 VanDerWaalsContact CE1-CD1 3.43Å; F102-I408 HydrophobicContact CZ-CD1 3.53Å
103	S	94.2	Very high	92	Very high	57 Å²	57	36 Å²	36	40%	0.399	19%	0.186	S	C	.	.	H	α-helix	trans	-67.1	-46.2	-179.2	-58.1	0	0	0	0	111.9	I99 Y100 Y101 I107	I99-S103 VanDerWaalsContact O-CB 3.32Å; I99-S103 WeakPolarHBondContact O-CB 3.41Å; I99-S103 PolarHBondContact O-N 2.99Å; I99-S103 VanDerWaalsContact O-N 3.1Å; I99-S103 PolarHBondContact O-OG 2.79Å; Y100-S103 WeakPolarHBondContact O-CB 3.48Å; Y100-S103 PolarHBondContact O-N 2.87Å; Y100-S103 VanDerWaalsContact O-N 3.12Å; Y101-S103 VanDerWaalsContact C-N 3.28Å; Y101-S103 PolarHBondContact O-N 3.25Å; S103-I107 WeakPolarHBondContact O-CD1 3.38Å; S103-I107 WeakPolarHBondContact O-CG1 3.42Å; S103-I107 PolarHBondContact O-N 3.35Å; S103-I107 VanDerWaalsContact O-N 3.08Å
104	T	96.2	Very high	92.8	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-66.1	-40.9	178.7	53.3	0	0	0	0	111.6	Y100 Y101 I106 I107 A108 L303 I306 N368 D370	Y100-T104 HydrophobicContact CD2-CG2 3.94Å; Y100-T104 HydrophobicContact CE1-CG2 4.22Å; Y100-T104 HydrophobicContact CE2-CG2 3.44Å; Y100-T104 VanDerWaalsContact CE2-CG2 3.44Å; Y100-T104 PolarHBondContact O-N 2.85Å; Y100-T104 PolarHBondContact O-OG1 3.36Å; Y101-T104 PolarHBondContact O-N 3.38Å; Y101-T104 PolarHBondContact O-OG1 3.44Å; Y101-T104 VanDerWaalsContact O-OG1 3.11Å; T104-I106 PolarHBondContact O-N 3.17Å; T104-I107 PolarHBondContact O-N 3.21Å; T104-A108 WeakPolarHBondContact O-CB 3.44Å; T104-A108 PolarHBondContact O-N 3.11Å; T104-L303 HydrophobicContact CG2-CD2 3.76Å; T104-I306 HydrophobicContact CG2-CD1 4.05Å; T104-N368 PolarHBondContact OG1-OD1 3.44Å; T104-D370 WeakPolarHBondContact CB-OD1 3.44Å; T104-D370 PolarHBondContact OG1-OD1 3.42Å
105	T	94.6	Very high	93.7	Very high	3 Å²	3	41.3 Å²	41.3	2%	0.018	21%	0.211	C	C	.	.	H	α-helix	trans	-64.1	-44.9	-179.8	-57.6	0	0	0	0	110.8	Y101 I107 A108 V109 D370 A373 T404 S407	Y101-T105 VanDerWaalsContact O-CB 3.3Å; Y101-T105 WeakPolarHBondContact O-CB 3.35Å; Y101-T105 PolarHBondContact O-N 3.37Å; Y101-T105 PolarHBondContact O-OG1 3.49Å; T105-I107 VanDerWaalsContact C-N 3.34Å; T105-I107 PolarHBondContact O-N 2.99Å; T105-A108 WeakPolarHBondContact O-CB 3.22Å; T105-A108 PolarHBondContact O-N 3.18Å; T105-V109 WeakPolarHBondContact O-CG2 3.46Å; T105-V109 PolarHBondContact O-N 3.17Å; T105-D370 VanDerWaalsContact CA-OD1 3.31Å; T105-D370 WeakPolarHBondContact CA-OD1 3.43Å; T105-D370 PolarHBondContact N-OD1 3.36Å; T105-D370 PolarHBondContact OG1-OD1 3.31Å; T105-A373 HydrophobicContact CG2-CB 3.47Å; T105-A373 VanDerWaalsContact CG2-CB 3.47Å; T105-T404 HydrophobicContact CG2-CG2 3.92Å; T105-S407 WeakPolarHBondContact CG2-OG 3.26Å
106	I	95.1	Very high	94.3	Very high	72 Å²	72	36.2 Å²	36.2	37%	0.369	19%	0.185	S	C	.	.	H	α-helix	trans	-61.7	-42.5	175.5	-70.6	167.4	0	0	0	110.9	F102 T104 A108 V109 I110 T404	F102-I106 WeakPolarHBondContact O-CB 3.28Å; F102-I106 WeakPolarHBondContact O-CD1 3.4Å; F102-I106 WeakPolarHBondContact O-CG1 3.49Å; F102-I106 PolarHBondContact O-N 3.33Å; T104-I106 PolarHBondContact O-N 3.17Å; I106-A108 VanDerWaalsContact C-N 3.33Å; I106-A108 PolarHBondContact O-N 2.83Å; I106-V109 PolarHBondContact O-N 3.38Å; I106-I110 HydrophobicContact CG2-CD1 3.7Å; I106-I110 HydrophobicContact CG2-CG1 4.36Å; I106-I110 WeakPolarHBondContact O-CB 3.31Å; I106-I110 VanDerWaalsContact O-CG1 3.29Å; I106-I110 WeakPolarHBondContact O-CG1 3.1Å; I106-I110 PolarHBondContact O-N 2.9Å; I106-T404 HydrophobicContact CG1-CG2 4.06Å
107	I	96.8	Very high	94.4	Very high	66 Å²	66	36.4 Å²	36.4	34%	0.338	19%	0.189	S	C	.	.	H	α-helix	trans	-62.1	-41.6	176.5	-69.8	166	0	0	0	110.9	S103 T104 T105 L111 C302 I306	S103-I107 WeakPolarHBondContact O-CD1 3.38Å; S103-I107 WeakPolarHBondContact O-CG1 3.42Å; S103-I107 PolarHBondContact O-N 3.35Å; S103-I107 VanDerWaalsContact O-N 3.08Å; T104-I107 PolarHBondContact O-N 3.21Å; T105-I107 VanDerWaalsContact C-N 3.34Å; T105-I107 PolarHBondContact O-N 2.99Å; I107-L111 WeakPolarHBondContact O-CB 3.47Å; I107-L111 PolarHBondContact O-N 3.25Å; I107-C302 HydrophobicContact CG2-CB 4.34Å; I107-I306 HydrophobicContact CD1-CD1 3.88Å
108	A	97.4	Very high	94.7	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-62.9	-44.4	177.3	0	0	0	0	0	111.8	T104 T105 I106 L111 G112 D370 L374	T104-A108 WeakPolarHBondContact O-CB 3.44Å; T104-A108 PolarHBondContact O-N 3.11Å; T105-A108 WeakPolarHBondContact O-CB 3.22Å; T105-A108 PolarHBondContact O-N 3.18Å; I106-A108 VanDerWaalsContact C-N 3.33Å; I106-A108 PolarHBondContact O-N 2.83Å; A108-L111 PolarHBondContact O-N 2.78Å; A108-G112 PolarHBondContact O-N 3.3Å; A108-D370 HydrophobicContact CB-CB 4.07Å; A108-D370 WeakPolarHBondContact CB-O 3.49Å; A108-L374 HydrophobicContact CB-CB 4.23Å; A108-L374 WeakPolarHBondContact O-CD1 3.38Å
109	V	96.7	Very high	95.1	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-62.3	-49.5	176.3	169.7	0	0	0	0	111.3	T105 I106 L111 G112 I113 A373 A377 S400 A403	T105-V109 WeakPolarHBondContact O-CG2 3.46Å; T105-V109 PolarHBondContact O-N 3.17Å; I106-V109 PolarHBondContact O-N 3.38Å; V109-L111 VanDerWaalsContact C-N 3.3Å; V109-L111 PolarHBondContact O-N 3.02Å; V109-G112 PolarHBondContact O-N 3.35Å; V109-G112 VanDerWaalsContact O-N 3.12Å; V109-I113 HydrophobicContact CG1-CD1 3.85Å; V109-I113 HydrophobicContact CG1-CG1 4.42Å; V109-I113 WeakPolarHBondContact O-CG1 3.18Å; V109-I113 PolarHBondContact O-N 3.12Å; V109-A373 HydrophobicContact CG2-CB 3.47Å; V109-A373 VanDerWaalsContact CG2-CB 3.47Å; V109-A377 HydrophobicContact CG1-CB 4.02Å; V109-S400 VanDerWaalsContact CG1-OG 3.3Å; V109-S400 WeakPolarHBondContact CG1-OG 3.18Å; V109-A403 HydrophobicContact CG2-CB 4.31Å
110	I	96.6	Very high	95.2	Very high	82 Å²	82	43.1 Å²	43.1	42%	0.421	22%	0.223	S	C	.	.	H	α-helix	trans	-58.8	-44.6	178.3	-70	169.2	0	0	0	110.5	I106 G112 I113 I114	I106-I110 HydrophobicContact CG2-CD1 3.7Å; I106-I110 HydrophobicContact CG2-CG1 4.36Å; I106-I110 WeakPolarHBondContact O-CB 3.31Å; I106-I110 VanDerWaalsContact O-CG1 3.29Å; I106-I110 WeakPolarHBondContact O-CG1 3.1Å; I106-I110 PolarHBondContact O-N 2.9Å; I110-G112 VanDerWaalsContact C-N 3.34Å; I110-G112 PolarHBondContact O-N 3.08Å; I110-I113 PolarHBondContact O-N 3.33Å; I110-I114 HydrophobicContact CG2-CD1 3.72Å; I110-I114 HydrophobicContact CG2-CG1 4.4Å; I110-I114 VanDerWaalsContact O-CG1 3.28Å; I110-I114 WeakPolarHBondContact O-CG1 3.42Å; I110-I114 PolarHBondContact O-N 3.08Å
111	L	97.6	Very high	94.9	Very high	28 Å²	28	42.4 Å²	42.4	15%	0.147	22%	0.22	C	C	.	.	H	α-helix	trans	-59.2	-45.5	175.7	176.6	66.4	0	0	0	111.5	I107 A108 V109 I114 L115 I297 H298 L374	I107-L111 WeakPolarHBondContact O-CB 3.47Å; I107-L111 PolarHBondContact O-N 3.25Å; A108-L111 PolarHBondContact O-N 2.78Å; V109-L111 VanDerWaalsContact C-N 3.3Å; V109-L111 PolarHBondContact O-N 3.02Å; L111-I114 PolarHBondContact O-N 3.44Å; L111-L115 HydrophobicContact CD1-CD1 4.05Å; L111-L115 HydrophobicContact CD1-CG 4.3Å; L111-L115 HydrophobicContact CG-CD1 4.02Å; L111-L115 WeakPolarHBondContact O-CB 3.34Å; L111-L115 WeakPolarHBondContact O-CG 3.42Å; L111-L115 PolarHBondContact O-N 3.15Å; L111-I297 HydrophobicContact CD1-CG2 3.97Å; L111-I297 HydrophobicContact CD2-CB 4.15Å; L111-I297 HydrophobicContact CD2-CG2 3.78Å; L111-H298 HydrophobicContact CD2-CB 3.87Å; L111-L374 HydrophobicContact CD2-CD1 4.17Å; L111-L374 HydrophobicContact CG-CD1 4.48Å
112	G	97.2	Very high	94.5	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-58	-48.9	176.3	0	0	0	0	0	112.4	A108 V109 I110 I114 L115 V116 V378	A108-G112 PolarHBondContact O-N 3.3Å; V109-G112 PolarHBondContact O-N 3.35Å; V109-G112 VanDerWaalsContact O-N 3.12Å; I110-G112 VanDerWaalsContact C-N 3.34Å; I110-G112 PolarHBondContact O-N 3.08Å; G112-I114 PolarHBondContact O-N 3.3Å; G112-L115 PolarHBondContact O-N 3.22Å; G112-V116 WeakPolarHBondContact O-CG1 3.45Å; G112-V116 PolarHBondContact O-N 3.5Å; G112-V378 WeakPolarHBondContact O-CG2 3.48Å
113	I	96.3	Very high	94.2	Very high	20 Å²	20	41 Å²	41	10%	0.103	22%	0.219	C	C	.	.	H	α-helix	trans	-59.6	-47.6	177.6	-66.1	173.5	0	0	0	110.8	V109 I110 L115 V116 M117 A377 I381 I396	V109-I113 HydrophobicContact CG1-CD1 3.85Å; V109-I113 HydrophobicContact CG1-CG1 4.42Å; V109-I113 WeakPolarHBondContact O-CG1 3.18Å; V109-I113 PolarHBondContact O-N 3.12Å; I110-I113 PolarHBondContact O-N 3.33Å; I113-L115 VanDerWaalsContact C-N 3.33Å; I113-L115 PolarHBondContact O-N 3.13Å; I113-V116 WeakPolarHBondContact O-CG1 3.37Å; I113-M117 HydrophobicContact CG2-CG 4.19Å; I113-M117 VanDerWaalsContact O-CB 3.26Å; I113-M117 WeakPolarHBondContact O-CB 3.38Å; I113-M117 WeakPolarHBondContact O-CG 3.25Å; I113-M117 PolarHBondContact O-N 3.47Å; I113-A377 HydrophobicContact CG1-CB 3.93Å; I113-I381 HydrophobicContact CB-CD1 4.17Å; I113-I381 HydrophobicContact CG1-CD1 3.83Å; I113-I381 HydrophobicContact CG2-CD1 3.96Å; I113-I396 HydrophobicContact CD1-CG2 4.2Å; I113-I396 HydrophobicContact CG2-CG2 3.75Å
114	I	96.6	Very high	93	Very high	97 Å²	97	39.8 Å²	39.8	50%	0.497	21%	0.211	S	C	.	.	H	α-helix	trans	-59	-46.6	178.1	-69.5	167.8	0	0	0	110.1	I110 L111 G112 T118	I110-I114 HydrophobicContact CG2-CD1 3.72Å; I110-I114 HydrophobicContact CG2-CG1 4.4Å; I110-I114 VanDerWaalsContact O-CG1 3.28Å; I110-I114 WeakPolarHBondContact O-CG1 3.42Å; I110-I114 PolarHBondContact O-N 3.08Å; L111-I114 PolarHBondContact O-N 3.44Å; G112-I114 PolarHBondContact O-N 3.3Å; I114-T118 WeakPolarHBondContact O-CB 3.23Å; I114-T118 PolarHBondContact O-N 3.36Å; I114-T118 PolarHBondContact O-OG1 3.02Å
115	L	96.7	Very high	91.2	Very high	28 Å²	28	46.6 Å²	46.6	15%	0.147	24%	0.242	C	C	.	.	H	α-helix	trans	-65.6	-47.1	-177.5	-75	170.8	0	0	0	112.5	L111 G112 I113 M117 T118 I119 T290 I297	L111-L115 HydrophobicContact CD1-CD1 4.05Å; L111-L115 HydrophobicContact CD1-CG 4.3Å; L111-L115 HydrophobicContact CG-CD1 4.02Å; L111-L115 WeakPolarHBondContact O-CB 3.34Å; L111-L115 WeakPolarHBondContact O-CG 3.42Å; L111-L115 PolarHBondContact O-N 3.15Å; G112-L115 PolarHBondContact O-N 3.22Å; I113-L115 VanDerWaalsContact C-N 3.33Å; I113-L115 PolarHBondContact O-N 3.13Å; L115-M117 PolarHBondContact O-N 2.8Å; L115-T118 PolarHBondContact O-N 3.31Å; L115-I119 WeakPolarHBondContact O-CB 3.47Å; L115-I119 WeakPolarHBondContact O-CG1 3.24Å; L115-I119 PolarHBondContact O-N 2.85Å; L115-T290 HydrophobicContact CB-CG2 4.26Å; L115-I297 HydrophobicContact CD1-CD1 4.19Å; L115-I297 HydrophobicContact CD2-CD1 4.29Å
116	V	96.1	Very high	89.2	Confident	0 Å²	0	55.7 Å²	55.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-69.9	-33.2	-177.8	70.3	0	0	0	0	112.8	G112 I113 T118 K120 P121 T290 V378 I381 F382 Q385	G112-V116 WeakPolarHBondContact O-CG1 3.45Å; G112-V116 PolarHBondContact O-N 3.5Å; I113-V116 WeakPolarHBondContact O-CG1 3.37Å; V116-T118 VanDerWaalsContact C-N 3.31Å; V116-K120 VanDerWaalsContact O-CA 3.31Å; V116-K120 WeakPolarHBondContact O-CA 3.49Å; V116-K120 PolarHBondContact O-N 3.19Å; V116-P121 HydrophobicContact CG2-CG 3.81Å; V116-T290 HydrophobicContact CB-CG2 4.17Å; V116-V378 HydrophobicContact CB-CB 4.4Å; V116-V378 HydrophobicContact CB-CG1 4.04Å; V116-V378 HydrophobicContact CB-CG2 4.28Å; V116-V378 HydrophobicContact CG2-CG1 3.99Å; V116-I381 HydrophobicContact CB-CG2 4.46Å; V116-I381 HydrophobicContact CG1-CB 3.7Å; V116-I381 HydrophobicContact CG1-CD1 3.55Å; V116-I381 HydrophobicContact CG1-CG1 4.2Å; V116-I381 HydrophobicContact CG1-CG2 3.67Å; V116-I381 HydrophobicContact CG2-CB 4.17Å; V116-I381 HydrophobicContact CG2-CG2 3.97Å; V116-F382 HydrophobicContact CG2-CB 4.46Å; V116-Q385 PolarHBondContact O-NE2 3.42Å
117	M	93.2	Very high	86.8	Confident	73 Å²	73	54.6 Å²	54.6	36%	0.36	29%	0.286	S	S	.	.	H	α-helix	trans	-72.2	-27.4	174.3	-67.9	-65	-73.6	0	0	112.1	I113 L115 K120 I381 I396	I113-M117 HydrophobicContact CG2-CG 4.19Å; I113-M117 VanDerWaalsContact O-CB 3.26Å; I113-M117 WeakPolarHBondContact O-CB 3.38Å; I113-M117 WeakPolarHBondContact O-CG 3.25Å; I113-M117 PolarHBondContact O-N 3.47Å; L115-M117 PolarHBondContact O-N 2.8Å; M117-K120 VanDerWaalsContact O-CE 3.29Å; M117-K120 WeakPolarHBondContact O-CE 3.38Å; M117-K120 VanDerWaalsContact O-CG 3.23Å; M117-K120 WeakPolarHBondContact O-CG 3.03Å; M117-I381 HydrophobicContact CG-CD1 4.43Å; M117-I381 HydrophobicContact SD-CG2 3.77Å; M117-I396 HydrophobicContact CE-CD1 3.92Å
118	T	93.9	Very high	84.3	Confident	108 Å²	108	60.1 Å²	60.1	66%	0.663	31%	0.311	S	S	*	.	H	α-helix	trans	-80.9	-48.6	177	-53.7	0	0	0	0	111.7	I114 L115 V116	I114-T118 WeakPolarHBondContact O-CB 3.23Å; I114-T118 PolarHBondContact O-N 3.36Å; I114-T118 PolarHBondContact O-OG1 3.02Å; L115-T118 PolarHBondContact O-N 3.31Å; V116-T118 VanDerWaalsContact C-N 3.31Å
119	I	93.9	Very high	81.6	Confident	59 Å²	59	67.6 Å²	67.6	30%	0.303	35%	0.35	S	S	.	.	H	α-helix	trans	-77.2	-32.2	-176.1	-65.4	169.5	0	0	0	111.4	L115 L286 T290	L115-I119 WeakPolarHBondContact O-CB 3.47Å; L115-I119 WeakPolarHBondContact O-CG1 3.24Å; L115-I119 PolarHBondContact O-N 2.85Å; I119-L286 HydrophobicContact CG2-CD1 3.8Å; I119-L286 HydrophobicContact CG2-CD2 4.11Å; I119-L286 HydrophobicContact CG2-CG 3.82Å; I119-T290 HydrophobicContact CD1-CG2 4.07Å; I119-T290 WeakPolarHBondContact CG2-OG1 3.4Å
120	K	92.3	Very high	79	Confident	109 Å²	109	72.8 Å²	72.8	47%	0.474	38%	0.377	S	S	.	.			trans	49.3	63.4	-176.9	-58.8	-176.7	177.8	177.6	0	113.3	V116 M117 G122 V123 Q385	V116-K120 VanDerWaalsContact O-CA 3.31Å; V116-K120 WeakPolarHBondContact O-CA 3.49Å; V116-K120 PolarHBondContact O-N 3.19Å; M117-K120 VanDerWaalsContact O-CE 3.29Å; M117-K120 WeakPolarHBondContact O-CE 3.38Å; M117-K120 VanDerWaalsContact O-CG 3.23Å; M117-K120 WeakPolarHBondContact O-CG 3.03Å; K120-G122 VanDerWaalsContact C-N 3.26Å; K120-G122 PolarHBondContact O-N 3.08Å; K120-V123 HydrophobicContact CB-CG1 4.44Å; K120-V123 HydrophobicContact CB-CG2 3.83Å; K120-V123 WeakPolarHBondContact O-CG2 3.41Å; K120-Q385 VanDerWaalsContact C-OE1 3.29Å
121	P	89.9	Confident	76.1	Confident	1 Å²	1	77 Å²	77	1%	0.006	40%	0.401	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.5	-23	-175.4	20.5	-28.1	0	0	0	115.5	V116 L286 F382	V116-P121 HydrophobicContact CG2-CG 3.81Å; P121-L286 HydrophobicContact CB-CB 4.06Å; P121-L286 HydrophobicContact CB-CD2 4.26Å; P121-L286 HydrophobicContact CB-CG 3.92Å; P121-F382 HydrophobicContact CB-CD2 3.82Å; P121-F382 HydrophobicContact CB-CE2 4.12Å; P121-F382 HydrophobicContact CG-CD2 3.78Å
122	G	82.4	Confident	73.5	Confident	0 Å²	0	83.6 Å²	83.6	0%	0	42%	0.424	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.8	-16.3	-173.9	0	0	0	0	0	115.5	K120 K283	K120-G122 VanDerWaalsContact C-N 3.26Å; K120-G122 PolarHBondContact O-N 3.08Å; G122-K283 WeakPolarHBondContact O-CD 3.31Å; G122-K283 WeakPolarHBondContact O-CE 3.48Å; G122-K283 PolarHBondContact O-NZ 2.89Å
123	V	84.2	Confident	70.5	Confident	57 Å²	57	88.6 Å²	88.6	35%	0.345	46%	0.464	S	S	.	.	S	Bend	trans	-79.9	138.8	-178.6	-54.9	0	0	0	0	110.9	K120 Q385	K120-V123 HydrophobicContact CB-CG1 4.44Å; K120-V123 HydrophobicContact CB-CG2 3.83Å; K120-V123 WeakPolarHBondContact O-CG2 3.41Å; V123-Q385 HydrophobicContact CG1-CB 4.3Å; V123-Q385 HydrophobicContact CG1-CG 4.4Å
124	S	68.4	Low	67.7	Low	33 Å²	33	90.4 Å²	90.4	23%	0.231	49%	0.489	C	S	.	.			trans	-70.6	130.6	172	-72.4	0	0	0	0	109.1	E126 E279 K283	S124-E126 PolarHBondContact O-N 3.49Å; S124-E279 WeakPolarHBondContact CA-OE1 3.4Å; S124-E279 WeakPolarHBondContact CB-OE1 3.37Å; S124-E279 PolarHBondContact OG-OE1 2.8Å; S124-E279 PolarHBondContact OG-OE2 3.4Å; S124-K283 WeakPolarHBondContact OG-CE 3.21Å; S124-K283 PolarHBondContact OG-NZ 3.24Å
125	Q	59	Low	64.9	Low	143 Å²	143	92.5 Å²	92.5	67%	0.668	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.7	-8.5	-178.2	-76.5	-176	-10.3	0	0	112.9
126	E	53.6	Low	62.4	Low	194 Å²	194	95 Å²	95	91%	0.907	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.3	7.5	-179.1	-67.8	-173.8	163.1	0	0	114.4	S124 E128	S124-E126 PolarHBondContact O-N 3.49Å; E126-E128 PolarHBondContact O-N 3.44Å
127	A	44.1	Very low	60.2	Low	48 Å²	48	98.3 Å²	98.3	40%	0.397	54%	0.544	S	S	.	.			trans	-104.2	81.3	-176.7	0	0	0	0	0	111.8	I130	A127-I130 HydrophobicContact CB-CD1 4.19Å; A127-I130 HydrophobicContact CB-CG1 4.17Å
128	E	43.4	Very low	58.2	Low	183 Å²	183	102 Å²	102	86%	0.855	57%	0.565	S	S	*	*	S	Bend	trans	-78.4	-5.3	163.1	-136.5	177.3	-158	0	0	112.3	E126	E126-E128 PolarHBondContact O-N 3.44Å
129	N	42.4	Very low	56.6	Low	156 Å²	156	98.6 Å²	98.6	83%	0.834	54%	0.544	S	S	*	.			trans	-159.4	83.8	174.9	-75.3	-63.4	0	0	0	112.2
130	I	41.4	Very low	55.2	Low	110 Å²	110	98.1 Å²	98.1	56%	0.564	54%	0.544	S	S	*	.			trans	-132.2	96	157.9	-53.3	-179.2	0	0	0	107.7	A127 R132	A127-I130 HydrophobicContact CB-CD1 4.19Å; A127-I130 HydrophobicContact CB-CG1 4.17Å; I130-R132 VanDerWaalsContact C-N 3.27Å; I130-R132 HydrophobicContact CG2-CG 3.92Å; I130-R132 PolarHBondContact O-N 2.97Å
131	D	34.8	Very low	53.9	Low	171 Å²	171	94.9 Å²	94.9	91%	0.914	53%	0.534	S	S	*	.			trans	-66.5	87.4	166.2	-104.6	-19.6	0	0	0	108.6	A133	D131-A133 PolarHBondContact O-N 3.5Å
132	R	44.6	Very low	52.9	Low	166 Å²	166	98.9 Å²	98.9	63%	0.626	56%	0.558	S	S	*	*			trans	-81.3	99.5	160.9	-76.4	-173.7	172.5	156.9	-0.7	107.3	I130 G134	I130-R132 VanDerWaalsContact C-N 3.27Å; I130-R132 HydrophobicContact CG2-CG 3.92Å; I130-R132 PolarHBondContact O-N 2.97Å; R132-G134 PolarHBondContact O-N 3.28Å
133	A	33.8	Very low	52.4	Low	104 Å²	104	99.2 Å²	99.2	86%	0.86	56%	0.559	S	S	*	*			trans	-66.6	72.4	174.4	0	0	0	0	0	111.4	D131	D131-A133 PolarHBondContact O-N 3.5Å
134	G	37.6	Very low	51.6	Low	59 Å²	59	96.9 Å²	96.9	61%	0.608	55%	0.545	S	S	*	.			trans	-80.9	118.3	159.2	0	0	0	0	0	108.3	R132 T136	R132-G134 PolarHBondContact O-N 3.28Å; G134-T136 PolarHBondContact O-N 3.46Å
135	T	37.5	Very low	51.5	Low	140 Å²	140	99.1 Å²	99.1	86%	0.859	55%	0.554	S	S	*	*			trans	-60.2	103.6	166.8	39.8	0	0	0	0	108.3	P137	T135-P137 WeakPolarHBondContact O-CD 3.25Å
136	T	44.8	Very low	52.4	Low	80 Å²	80	95.4 Å²	95.4	49%	0.491	54%	0.539	S	S	.	.			trans	-62.5	122.3	172	46.8	0	0	0	0	107.5	G134 N138 Y389	G134-T136 PolarHBondContact O-N 3.46Å; T136-N138 PolarHBondContact O-N 2.97Å; T136-Y389 HydrophobicContact CG2-CD2 4.31Å; T136-Y389 HydrophobicContact CG2-CE2 4.32Å
137	P	49.5	Very low	53.3	Low	70 Å²	70	86.9 Å²	86.9	46%	0.455	50%	0.499	S	S	.	.			trans	-62.2	125.9	171.8	25.8	-31.6	0	0	0	107.3	T135 V139	T135-P137 WeakPolarHBondContact O-CD 3.25Å; P137-V139 HydrophobicContact CB-CG2 3.89Å; P137-V139 HydrophobicContact CG-CG2 4.23Å; P137-V139 PolarHBondContact O-N 3.45Å
138	N	51.5	Low	54.6	Low	151 Å²	151	85.5 Å²	85.5	81%	0.807	49%	0.485	S	S	*	.			trans	-66.2	68.7	175	-77.6	-29.5	0	0	0	110	T136	T136-N138 PolarHBondContact O-N 2.97Å
139	V	58.9	Low	56.3	Low	36 Å²	36	81 Å²	81	22%	0.218	47%	0.466	C	S	.	.			trans	-99.6	110.9	174.8	-166.2	0	0	0	0	106.7	P137 T144	P137-V139 HydrophobicContact CB-CG2 3.89Å; P137-V139 HydrophobicContact CG-CG2 4.23Å; P137-V139 PolarHBondContact O-N 3.45Å; V139-T144 HydrophobicContact CG1-CG2 3.46Å; V139-T144 VanDerWaalsContact CG1-CG2 3.46Å
140	T	65.1	Low	58.2	Low	50 Å²	50	77.8 Å²	77.8	31%	0.307	44%	0.443	S	S	.	.			trans	-74.5	145.4	173.1	52	0	0	0	0	110.5	V142 D143 T144 R169	T140-V142 PolarHBondContact O-N 3.16Å; T140-D143 WeakPolarHBondContact O-CB 3.48Å; T140-D143 PolarHBondContact O-N 2.93Å; T140-D143 PolarHBondContact OG1-OD1 3.39Å; T140-D143 PolarHBondContact OG1-OD2 2.98Å; T140-D143 VanDerWaalsContact OG1-OD2 3.09Å; T140-T144 PolarHBondContact O-N 3.3Å; T140-R169 PolarHBondContact OG1-NH2 3.01Å
141	T	64.1	Low	59.8	Low	41 Å²	41	73.4 Å²	73.4	25%	0.252	42%	0.421	S	S	.	.	H	α-helix	trans	-54.6	-36.6	178.9	52.5	0	0	0	0	113.5	D143 T144 L145 D392 Q395	T141-D143 PolarHBondContact O-N 3.42Å; T141-T144 PolarHBondContact O-N 3.11Å; T141-T144 PolarHBondContact O-OG1 3.36Å; T141-L145 PolarHBondContact O-N 2.99Å; T141-D392 HydrophobicContact CG2-CB 4.11Å; T141-D392 VanDerWaalsContact CG2-OD2 3.32Å; T141-D392 WeakPolarHBondContact CG2-OD2 3.14Å; T141-Q395 HydrophobicContact CG2-CG 3.93Å
142	V	69.8	Low	62	Low	85 Å²	85	67.8 Å²	67.8	52%	0.515	39%	0.389	S	S	.	.	H	α-helix	trans	-60.1	-45.2	176	-178.5	0	0	0	0	111.5	T140 T144 L145 L146	T140-V142 PolarHBondContact O-N 3.16Å; V142-T144 VanDerWaalsContact C-N 3.32Å; V142-T144 PolarHBondContact O-N 3.31Å; V142-L145 PolarHBondContact O-N 3.33Å; V142-L146 HydrophobicContact CG1-CD1 3.92Å; V142-L146 HydrophobicContact CG1-CG 4.3Å; V142-L146 VanDerWaalsContact O-CG 3.27Å; V142-L146 WeakPolarHBondContact O-CG 3.36Å; V142-L146 PolarHBondContact O-N 3.48Å
143	D	71.8	Confident	64.2	Low	6 Å²	6	66.9 Å²	66.9	3%	0.032	39%	0.39	C	S	.	.	H	α-helix	trans	-63.3	-40.6	180	-66.2	-3.8	0	0	0	110.8	T140 T141 L146 D147 R169	T140-D143 WeakPolarHBondContact O-CB 3.48Å; T140-D143 PolarHBondContact O-N 2.93Å; T140-D143 PolarHBondContact OG1-OD1 3.39Å; T140-D143 PolarHBondContact OG1-OD2 2.98Å; T140-D143 VanDerWaalsContact OG1-OD2 3.09Å; T141-D143 PolarHBondContact O-N 3.42Å; D143-L146 PolarHBondContact O-N 3.46Å; D143-D147 WeakPolarHBondContact O-CB 3.35Å; D143-D147 VanDerWaalsContact O-CG 3.23Å; D143-D147 PolarHBondContact O-N 3.34Å; D143-R169 IonicContact OD1-CZ 3.12Å; D143-R169 IonicContact OD1-NE 3.91Å; D143-R169 IonicContact OD1-NH2 2.78Å; D143-R169 PolarHBondContact OD1-NH2 3.3Å; D143-R169 IonicContact OD2-CZ 3.88Å; D143-R169 IonicContact OD2-NE 3.02Å; D143-R169 PolarHBondContact OD2-NE 3.44Å; D143-R169 IonicContact OD2-NH2 3.34Å; D143-R169 PolarHBondContact OD2-NH2 2.75Å
144	T	66.9	Low	66.7	Low	9 Å²	9	63.8 Å²	63.8	6%	0.055	36%	0.361	C	S	.	.	H	α-helix	trans	-63.9	-40.9	176.3	59.6	0	0	0	0	113.2	V139 T140 T141 V142 D147 L148 A427	V139-T144 HydrophobicContact CG1-CG2 3.46Å; V139-T144 VanDerWaalsContact CG1-CG2 3.46Å; T140-T144 PolarHBondContact O-N 3.3Å; T141-T144 PolarHBondContact O-N 3.11Å; T141-T144 PolarHBondContact O-OG1 3.36Å; V142-T144 VanDerWaalsContact C-N 3.32Å; V142-T144 PolarHBondContact O-N 3.31Å; T144-D147 PolarHBondContact O-N 2.93Å; T144-L148 PolarHBondContact O-N 3.22Å; T144-A427 WeakPolarHBondContact CB-O 3.31Å
145	L	66.8	Low	69.3	Low	79 Å²	79	68.3 Å²	68.3	41%	0.414	37%	0.367	S	S	.	.	H	α-helix	trans	-68.1	-40.7	178.4	-177.5	65.9	0	0	0	111.2	T141 V142 D147 L148 L149	T141-L145 PolarHBondContact O-N 2.99Å; V142-L145 PolarHBondContact O-N 3.33Å; L145-D147 VanDerWaalsContact C-N 3.34Å; L145-L148 WeakPolarHBondContact O-CB 3.21Å; L145-L148 PolarHBondContact O-N 2.85Å; L145-L149 PolarHBondContact O-N 3.46Å
146	L	78.2	Confident	72	Confident	66 Å²	66	65.3 Å²	65.3	35%	0.346	35%	0.345	S	S	.	.	H	α-helix	trans	-67.4	-37	175.8	-66.1	176.3	0	0	0	111.5	V142 D143 L148 L149 R150	V142-L146 HydrophobicContact CG1-CD1 3.92Å; V142-L146 HydrophobicContact CG1-CG 4.3Å; V142-L146 VanDerWaalsContact O-CG 3.27Å; V142-L146 WeakPolarHBondContact O-CG 3.36Å; V142-L146 PolarHBondContact O-N 3.48Å; D143-L146 PolarHBondContact O-N 3.46Å; L146-L148 VanDerWaalsContact C-N 3.34Å; L146-L149 PolarHBondContact O-N 3.48Å; L146-R150 VanDerWaalsContact O-CG 3.32Å; L146-R150 WeakPolarHBondContact O-CG 3.44Å; L146-R150 PolarHBondContact O-N 3.21Å
147	D	72.6	Confident	74.3	Confident	14 Å²	14	64.7 Å²	64.7	8%	0.075	34%	0.339	C	S	.	.	H	α-helix	trans	-68	-33.4	175.4	-75.4	-7.6	0	0	0	112.6	D143 T144 L145 R150 N151 T167	D143-D147 WeakPolarHBondContact O-CB 3.35Å; D143-D147 VanDerWaalsContact O-CG 3.23Å; D143-D147 PolarHBondContact O-N 3.34Å; T144-D147 PolarHBondContact O-N 2.93Å; L145-D147 VanDerWaalsContact C-N 3.34Å; D147-R150 PolarHBondContact O-N 3.46Å; D147-R150 IonicContact OD1-CZ 3.27Å; D147-R150 IonicContact OD1-NH1 3.86Å; D147-R150 PolarHBondContact OD1-NH1 3.46Å; D147-N151 WeakPolarHBondContact O-CB 3.4Å; D147-N151 PolarHBondContact O-N 3.44Å; D147-N151 PolarHBondContact O-ND2 3.49Å; D147-T167 VanDerWaalsContact CG-OG1 3.23Å; D147-T167 WeakPolarHBondContact OD1-CG2 3.42Å; D147-T167 PolarHBondContact OD1-OG1 2.93Å; D147-T167 WeakPolarHBondContact OD2-CB 3.41Å; D147-T167 PolarHBondContact OD2-N 2.98Å; D147-T167 PolarHBondContact OD2-OG1 3.25Å
148	L	71	Confident	76.5	Confident	19 Å²	19	66.3 Å²	66.3	10%	0.099	35%	0.347	C	S	.	.	H	α-helix	trans	-58.5	-49.5	170.5	-174.7	153.7	0	0	0	110.7	T144 L145 L146 N151 M152 L215 T398 I401 T402	T144-L148 PolarHBondContact O-N 3.22Å; L145-L148 WeakPolarHBondContact O-CB 3.21Å; L145-L148 PolarHBondContact O-N 2.85Å; L146-L148 VanDerWaalsContact C-N 3.34Å; L148-N151 PolarHBondContact O-N 3.27Å; L148-M152 HydrophobicContact CD2-CG 4.45Å; L148-M152 HydrophobicContact CD2-SD 4.02Å; L148-M152 WeakPolarHBondContact O-CG 3.41Å; L148-M152 PolarHBondContact O-N 3.44Å; L148-L215 HydrophobicContact CD2-CD2 4.35Å; L148-L215 HydrophobicContact CG-CD2 4.02Å; L148-T398 HydrophobicContact CD1-CG2 4.35Å; L148-I401 HydrophobicContact CD1-CG2 4.45Å; L148-T402 HydrophobicContact CD1-CG2 3.27Å; L148-T402 HydrophobicContact CG-CG2 4.41Å
149	L	78.4	Confident	78.4	Confident	88 Å²	88	61.2 Å²	61.2	46%	0.461	32%	0.318	S	S	.	.	H	α-helix	trans	-63.6	-41.1	177.4	-68.4	175	0	0	0	112.5	L145 L146 N151 M152	L145-L149 PolarHBondContact O-N 3.46Å; L146-L149 PolarHBondContact O-N 3.48Å; L149-N151 VanDerWaalsContact C-N 3.32Å; L149-N151 PolarHBondContact O-N 2.99Å; L149-M152 HydrophobicContact CD2-SD 4.02Å; L149-M152 WeakPolarHBondContact O-CB 3.36Å; L149-M152 PolarHBondContact O-N 3.19Å
150	R	82.3	Confident	79.5	Confident	89 Å²	89	59.6 Å²	59.6	34%	0.336	31%	0.309	S	S	.	.	H	α-helix	trans	-61.9	-41.1	175.3	-71.2	175.2	-171.1	108.8	7.2	111.6	L146 D147 M152 F153 Y165	L146-R150 VanDerWaalsContact O-CG 3.32Å; L146-R150 WeakPolarHBondContact O-CG 3.44Å; L146-R150 PolarHBondContact O-N 3.21Å; D147-R150 PolarHBondContact O-N 3.46Å; D147-R150 IonicContact OD1-CZ 3.27Å; D147-R150 IonicContact OD1-NH1 3.86Å; D147-R150 PolarHBondContact OD1-NH1 3.46Å; R150-M152 VanDerWaalsContact C-N 3.32Å; R150-M152 PolarHBondContact O-N 3.37Å; R150-F153 CarbonylContact O-C 3.54Å; R150-F153 PolarHBondContact O-N 3Å; R150-F153 VanDerWaalsContact O-O 3.13Å; R150-Y165 HydrophobicContact CB-CD1 4.18Å
151	N	76.1	Confident	80.3	Confident	19 Å²	19	58.6 Å²	58.6	10%	0.102	30%	0.304	C	S	.	.	H	α-helix	trans	-72.1	-22.6	178.8	-77.2	-58.9	0	0	0	113.2	D147 L148 L149 F153 Y165 N213 L215 G216	D147-N151 WeakPolarHBondContact O-CB 3.4Å; D147-N151 PolarHBondContact O-N 3.44Å; D147-N151 PolarHBondContact O-ND2 3.49Å; L148-N151 PolarHBondContact O-N 3.27Å; L149-N151 VanDerWaalsContact C-N 3.32Å; L149-N151 PolarHBondContact O-N 2.99Å; N151-F153 PolarHBondContact O-N 2.92Å; N151-Y165 PolarHBondContact ND2-O 3.46Å; N151-Y165 WeakPolarHBondContact OD1-CB 3.49Å; N151-Y165 PolarHBondContact OD1-N 3.08Å; N151-N213 PolarHBondContact O-ND2 2.98Å; N151-N213 PolarHBondContact O-OD1 3.36Å; N151-L215 HydrophobicContact CB-CD2 4.43Å; N151-G216 WeakPolarHBondContact O-CA 3.28Å; N151-G216 PolarHBondContact O-N 2.86Å
152	M	81.1	Confident	81.1	Confident	52 Å²	52	61.6 Å²	61.6	26%	0.256	31%	0.313	S	S	.	.	H	α-helix	trans	-63.4	-29.3	170.6	-70.9	178.1	67.5	0	0	112.8	L148 L149 R150 P154 L215 V219	L148-M152 HydrophobicContact CD2-CG 4.45Å; L148-M152 HydrophobicContact CD2-SD 4.02Å; L148-M152 WeakPolarHBondContact O-CG 3.41Å; L148-M152 PolarHBondContact O-N 3.44Å; L149-M152 HydrophobicContact CD2-SD 4.02Å; L149-M152 WeakPolarHBondContact O-CB 3.36Å; L149-M152 PolarHBondContact O-N 3.19Å; R150-M152 VanDerWaalsContact C-N 3.32Å; R150-M152 PolarHBondContact O-N 3.37Å; M152-P154 WeakPolarHBondContact O-CD 3.3Å; M152-L215 HydrophobicContact CG-CD1 4.14Å; M152-L215 HydrophobicContact CG-CD2 3.72Å; M152-L215 HydrophobicContact CG-CG 3.84Å; M152-V219 HydrophobicContact CB-CG2 4.19Å; M152-V219 HydrophobicContact CE-CG2 3.99Å; M152-V219 HydrophobicContact CG-CG2 4.23Å
153	F	89.7	Confident	81.6	Confident	148 Å²	148	59.8 Å²	59.8	65%	0.649	30%	0.299	S	S	*	.	S	Bend	trans	-122.8	76.2	-179.5	-58.7	-76.8	0	0	0	110.1	R150 N151 V219	R150-F153 CarbonylContact O-C 3.54Å; R150-F153 PolarHBondContact O-N 3Å; R150-F153 VanDerWaalsContact O-O 3.13Å; N151-F153 PolarHBondContact O-N 2.92Å; F153-V219 HydrophobicContact CE1-CG1 4.38Å
154	P	87.1	Confident	81.5	Confident	39 Å²	39	61.2 Å²	61.2	25%	0.253	31%	0.306	S	S	.	.			trans	-64.2	142	-178.3	26.7	-33.6	0	0	0	111.4	M152 N156 A160	M152-P154 WeakPolarHBondContact O-CD 3.3Å; P154-N156 PolarHBondContact O-N 2.82Å; P154-A160 HydrophobicContact CB-CB 3.85Å; P154-A160 HydrophobicContact CG-CB 4.01Å
155	E	91.6	Very high	82	Confident	154 Å²	154	63.3 Å²	63.3	72%	0.72	31%	0.313	S	S	*	.	S	Bend	trans	-63.1	-27.4	177.1	-64.4	179.5	167.2	0	0	112.3	Y208	E155-Y208 PolarHBondContact OE2-OH 2.93Å
156	N	94.9	Very high	82.3	Confident	77 Å²	77	63.1 Å²	63.1	41%	0.412	31%	0.309	S	S	.	.			trans	-146.2	129.3	178.8	-174.2	-52.8	0	0	0	111.5	P154 V158 Q159 A160	P154-N156 PolarHBondContact O-N 2.82Å; N156-V158 WeakPolarHBondContact OD1-CA 3.46Å; N156-V158 WeakPolarHBondContact OD1-CB 3.38Å; N156-V158 PolarHBondContact OD1-N 2.99Å; N156-Q159 HydrophobicContact CB-CB 3.81Å; N156-Q159 PolarHBondContact O-N 3.08Å; N156-Q159 PolarHBondContact OD1-N 3.35Å; N156-Q159 VanDerWaalsContact OD1-N 3.11Å; N156-A160 WeakPolarHBondContact O-CB 3.47Å; N156-A160 PolarHBondContact O-N 3.07Å
157	L	92.4	Very high	82.4	Confident	67 Å²	67	60.4 Å²	60.4	35%	0.351	30%	0.295	S	S	.	.	H	α-helix	trans	-68.7	-38.6	-177.7	-171.8	67.4	0	0	0	113.1	A160 C161 L217 F220	L157-A160 WeakPolarHBondContact O-CB 3.48Å; L157-A160 PolarHBondContact O-N 3.29Å; L157-C161 PolarHBondContact O-N 3.5Å; L157-C161 PolarHBondContact O-SG 3.38Å; L157-C161 VanDerWaalsContact O-SG 3.38Å; L157-L217 HydrophobicContact CD1-CD2 3.75Å; L157-F220 HydrophobicContact CD1-CB 4.13Å; L157-F220 HydrophobicContact CD1-CD1 3.7Å; L157-F220 HydrophobicContact CD1-CD2 4.27Å; L157-F220 HydrophobicContact CD1-CE1 4.2Å; L157-F220 HydrophobicContact CD1-CG 3.75Å; L157-F220 HydrophobicContact CD2-CD1 3.93Å; L157-F220 HydrophobicContact CD2-CE1 3.52Å; L157-F220 HydrophobicContact CD2-CE2 4.17Å; L157-F220 HydrophobicContact CD2-CG 4.41Å; L157-F220 HydrophobicContact CD2-CZ 3.66Å; L157-F220 HydrophobicContact CG-CD1 4.5Å
158	V	95.7	Very high	82.6	Confident	104 Å²	104	66.2 Å²	66.2	63%	0.63	32%	0.32	S	S	*	.	H	α-helix	trans	-68.4	-41.8	178	-178.7	0	0	0	0	109.9	N156 A160 C161 F162	N156-V158 WeakPolarHBondContact OD1-CA 3.46Å; N156-V158 WeakPolarHBondContact OD1-CB 3.38Å; N156-V158 PolarHBondContact OD1-N 2.99Å; V158-A160 VanDerWaalsContact C-N 3.31Å; V158-A160 PolarHBondContact O-N 3.15Å; V158-C161 VanDerWaalsContact O-CB 3.26Å; V158-C161 WeakPolarHBondContact O-CB 3.28Å; V158-C161 PolarHBondContact O-N 3.31Å; V158-C161 VanDerWaalsContact O-N 3.16Å; V158-F162 HydrophobicContact CG1-CE1 4.41Å; V158-F162 VanDerWaalsContact O-CD1 3.28Å; V158-F162 WeakPolarHBondContact O-CD1 3.48Å; V158-F162 WeakPolarHBondContact O-CE1 3.27Å
159	Q	91.3	Very high	82.7	Confident	43 Å²	43	70.5 Å²	70.5	20%	0.201	33%	0.334	C	S	.	.	H	α-helix	trans	-62.4	-38.9	175.1	-170.4	178.6	4.2	0	0	111.7	N156 C161 F162 Q163 Y208	N156-Q159 HydrophobicContact CB-CB 3.81Å; N156-Q159 PolarHBondContact O-N 3.08Å; N156-Q159 PolarHBondContact OD1-N 3.35Å; N156-Q159 VanDerWaalsContact OD1-N 3.11Å; Q159-C161 PolarHBondContact O-N 2.81Å; Q159-C161 VanDerWaalsContact O-N 3.11Å; Q159-F162 HydrophobicContact CG-CZ 4.41Å; Q159-F162 PolarHBondContact O-N 2.85Å; Q159-Q163 HydrophobicContact CG-CB 4Å; Q159-Q163 PolarHBondContact O-N 3.48Å; Q159-Y208 VanDerWaalsContact NE2-CD1 3.32Å; Q159-Y208 VanDerWaalsContact NE2-CG 3.33Å
160	A	83.6	Confident	82.7	Confident	2 Å²	2	73 Å²	73	2%	0.017	34%	0.342	C	S	.	.	H	α-helix	trans	-58.9	-23.3	176.4	0	0	0	0	0	113.2	P154 N156 L157 V158 F162 N213 L217	P154-A160 HydrophobicContact CB-CB 3.85Å; P154-A160 HydrophobicContact CG-CB 4.01Å; N156-A160 WeakPolarHBondContact O-CB 3.47Å; N156-A160 PolarHBondContact O-N 3.07Å; L157-A160 WeakPolarHBondContact O-CB 3.48Å; L157-A160 PolarHBondContact O-N 3.29Å; V158-A160 VanDerWaalsContact C-N 3.31Å; V158-A160 PolarHBondContact O-N 3.15Å; A160-F162 PolarHBondContact O-N 2.97Å; A160-N213 HydrophobicContact CB-CB 4.13Å; A160-N213 PolarHBondContact O-N 3.33Å; A160-L217 HydrophobicContact CB-CD2 4.3Å; A160-L217 HydrophobicContact CB-CG 4.48Å
161	C	81.9	Confident	82.4	Confident	30 Å²	30	73.1 Å²	73.1	20%	0.203	35%	0.346	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.1	-16	175.7	-61.2	0	0	0	0	113.9	L71 L157 V158 Q159 I212	L71-C161 HydrophobicContact CD1-CB 4.22Å; L71-C161 HydrophobicContact CD2-CB 3.83Å; L157-C161 PolarHBondContact O-N 3.5Å; L157-C161 PolarHBondContact O-SG 3.38Å; L157-C161 VanDerWaalsContact O-SG 3.38Å; V158-C161 VanDerWaalsContact O-CB 3.26Å; V158-C161 WeakPolarHBondContact O-CB 3.28Å; V158-C161 PolarHBondContact O-N 3.31Å; V158-C161 VanDerWaalsContact O-N 3.16Å; Q159-C161 PolarHBondContact O-N 2.81Å; Q159-C161 VanDerWaalsContact O-N 3.11Å; C161-I212 WeakPolarHBondContact O-CG1 3.25Å
162	F	80.2	Confident	82.3	Confident	104 Å²	104	76 Å²	76	46%	0.456	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-144.2	-7.7	-176.9	60.9	-89.2	0	0	0	115.4	V158 Q159 A160 G211	V158-F162 HydrophobicContact CG1-CE1 4.41Å; V158-F162 VanDerWaalsContact O-CD1 3.28Å; V158-F162 WeakPolarHBondContact O-CD1 3.48Å; V158-F162 WeakPolarHBondContact O-CE1 3.27Å; Q159-F162 HydrophobicContact CG-CZ 4.41Å; Q159-F162 PolarHBondContact O-N 2.85Å; A160-F162 PolarHBondContact O-N 2.97Å; F162-G211 CarbonylContact C-O 3.5Å; F162-G211 CarbonylContact O-C 3.33Å; F162-G211 PolarHBondContact O-N 2.83Å
163	Q	80.3	Confident	81.5	Confident	46 Å²	46	82 Å²	82	22%	0.215	39%	0.389	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.5	150.3	177.3	-76.8	170.7	2.1	0	0	112.9	Q159 Y208 S209 G211 N213	Q159-Q163 HydrophobicContact CG-CB 4Å; Q159-Q163 PolarHBondContact O-N 3.48Å; Q163-Y208 HydrophobicContact CB-CD1 4.25Å; Q163-S209 WeakPolarHBondContact CA-O 3.29Å; Q163-G211 CarbonylContact C-O 3.56Å; Q163-G211 WeakPolarHBondContact CA-O 3.49Å; Q163-G211 PolarHBondContact N-O 3.12Å; Q163-N213 WeakPolarHBondContact O-CB 3.43Å
164	Q	69.9	Low	80	Confident	37 Å²	37	79.1 Å²	79.1	17%	0.173	39%	0.385	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.5	148.1	175.7	67.3	-173.9	-14.9	0	0	111	Y208 S209 G211 N213	Q164-Y208 WeakPolarHBondContact O-CA 3.49Å; Q164-S209 WeakPolarHBondContact CG-OG 3.47Å; Q164-S209 PolarHBondContact N-O 3.4Å; Q164-S209 PolarHBondContact NE2-OG 2.96Å; Q164-S209 PolarHBondContact O-N 2.84Å; Q164-S209 PolarHBondContact O-OG 2.69Å; Q164-G211 PolarHBondContact N-O 3.41Å; Q164-N213 HydrophobicContact CB-CB 4.23Å
165	Y	77.5	Confident	78.3	Confident	52 Å²	52	80.5 Å²	80.5	20%	0.204	41%	0.406	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.4	131.3	-179.4	-166.8	-91.9	0	0	0	111	R150 N151 T167 G206 Y208	R150-Y165 HydrophobicContact CB-CD1 4.18Å; N151-Y165 PolarHBondContact ND2-O 3.46Å; N151-Y165 WeakPolarHBondContact OD1-CB 3.49Å; N151-Y165 PolarHBondContact OD1-N 3.08Å; Y165-T167 HydrophobicContact CE1-CG2 3.79Å; Y165-G206 VanDerWaalsContact OH-CA 3.29Å; Y165-G206 WeakPolarHBondContact OH-CA 3.38Å; Y165-Y208 HydrophobicContact CD2-CD1 4.44Å; Y165-Y208 AromaticContact CD2-CE1 3.96Å; Y165-Y208 HydrophobicContact CD2-CE1 3.96Å; Y165-Y208 HydrophobicContact CD2-CE2 4.17Å; Y165-Y208 AromaticContact CD2-CZ 3.82Å; Y165-Y208 HydrophobicContact CE2-CE2 4.5Å
166	K	72.8	Confident	76.3	Confident	76 Å²	76	83.3 Å²	83.3	33%	0.33	42%	0.416	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.2	130.4	175.6	-172	168	-175.1	167.9	0	110.6	A207	K166-A207 PolarHBondContact N-O 3.26Å; K166-A207 PolarHBondContact O-N 3.16Å
167	T	79.5	Confident	74	Confident	9 Å²	9	85.5 Å²	85.5	6%	0.055	43%	0.432	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.1	140.2	173.4	51.4	0	0	0	0	111.4	D147 Y165 I204	D147-T167 VanDerWaalsContact CG-OG1 3.23Å; D147-T167 WeakPolarHBondContact OD1-CG2 3.42Å; D147-T167 PolarHBondContact OD1-OG1 2.93Å; D147-T167 WeakPolarHBondContact OD2-CB 3.41Å; D147-T167 PolarHBondContact OD2-N 2.98Å; D147-T167 PolarHBondContact OD2-OG1 3.25Å; Y165-T167 HydrophobicContact CE1-CG2 3.79Å; T167-I204 HydrophobicContact CG2-CG2 3.59Å
168	K	76.6	Confident	71.8	Confident	136 Å²	136	89.1 Å²	89.1	59%	0.591	45%	0.451	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-124.4	132.1	170.6	-68	-176.9	179.4	179.5	0	108.6	K170 V205	K168-K170 PolarHBondContact O-N 2.92Å; K168-V205 PolarHBondContact N-O 3.16Å; K168-V205 PolarHBondContact O-N 2.91Å
169	R	74.2	Confident	69.5	Low	108 Å²	108	89 Å²	89	41%	0.408	45%	0.454	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	119.5	169.8	-67.5	-176.6	179.9	-157	-8.8	108.7	T140 D143 Y202	T140-R169 PolarHBondContact OG1-NH2 3.01Å; D143-R169 IonicContact OD1-CZ 3.12Å; D143-R169 IonicContact OD1-NE 3.91Å; D143-R169 IonicContact OD1-NH2 2.78Å; D143-R169 PolarHBondContact OD1-NH2 3.3Å; D143-R169 IonicContact OD2-CZ 3.88Å; D143-R169 IonicContact OD2-NE 3.02Å; D143-R169 PolarHBondContact OD2-NE 3.44Å; D143-R169 IonicContact OD2-NH2 3.34Å; D143-R169 PolarHBondContact OD2-NH2 2.75Å; R169-Y202 HydrophobicContact CB-CD1 4.27Å
170	K	77.8	Confident	67.3	Low	142 Å²	142	93.3 Å²	93.3	62%	0.617	48%	0.478	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-102	120.4	169.1	-170.9	175.6	179.8	179.8	0	107.8	K168 L172 K203 V205	K168-K170 PolarHBondContact O-N 2.92Å; K170-L172 PolarHBondContact O-N 3.44Å; K170-K203 PolarHBondContact N-O 3.28Å; K170-K203 PolarHBondContact O-N 3.06Å; K170-V205 HydrophobicContact CB-CG2 3.93Å
171	E	75.8	Confident	65.5	Low	91 Å²	91	98.9 Å²	98.9	43%	0.425	51%	0.512	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-63.5	129.8	171.1	-169	166.7	-172.1	0	0	108.7	E173 R200 Y202	E171-E173 PolarHBondContact O-N 3.3Å; E171-R200 VanDerWaalsContact OE1-CD 3.31Å; E171-R200 WeakPolarHBondContact OE1-CD 3.01Å; E171-R200 IonicContact OE1-NE 3.02Å; E171-Y202 HydrophobicContact CB-CD1 4.16Å; E171-Y202 HydrophobicContact CB-CE1 4.05Å; E171-Y202 HydrophobicContact CG-CE1 4.18Å
172	L	74.4	Confident	63.9	Low	78 Å²	78	103.4 Å²	103.4	41%	0.408	54%	0.539	S	S	.	.			trans	-80.7	115.8	171.7	-68.4	170.8	0	0	0	106.5	K170 E201 K203	K170-L172 PolarHBondContact O-N 3.44Å; L172-E201 HydrophobicContact CB-CB 4.33Å; L172-E201 HydrophobicContact CD1-CB 4.09Å; L172-E201 PolarHBondContact N-O 2.62Å; L172-K203 HydrophobicContact CD1-CB 4.23Å; L172-K203 HydrophobicContact CD2-CB 4.05Å; L172-K203 HydrophobicContact CD2-CD 4.46Å; L172-K203 HydrophobicContact CG-CB 4.07Å
173	E	65.3	Low	62.1	Low	180 Å²	180	104.3 Å²	104.3	84%	0.841	55%	0.554	S	S	*	*	P	Polyproline II helix	trans	-58.8	129.5	174.6	-67	-126.5	149.9	0	0	109	E171 G175	E171-E173 PolarHBondContact O-N 3.3Å; E173-G175 PolarHBondContact O-N 2.83Å
174	P	57.1	Low	60.5	Low	87 Å²	87	109.4 Å²	109.4	57%	0.565	58%	0.581	S	S	*	*	P	Polyproline II helix	trans	-58.8	128.9	175.2	23.2	-30.2	0	0	0	108	K176	P174-K176 PolarHBondContact O-N 3.39Å
175	G	52.8	Low	59.4	Low	68 Å²	68	113 Å²	113	70%	0.701	61%	0.607	S	S	*	*	P	Polyproline II helix	trans	-49.3	132.6	180	0	0	0	0	0	110.3	E173 V177	E173-G175 PolarHBondContact O-N 2.83Å; G175-V177 PolarHBondContact O-N 3.28Å
176	K	47.7	Very low	58.3	Low	213 Å²	213	116.1 Å²	116.1	93%	0.926	63%	0.634	S	S	*	*			trans	-43.8	109.9	-179.5	-76.8	179.1	176.1	178.6	0	110.2	P174 L178	P174-K176 PolarHBondContact O-N 3.39Å; K176-L178 PolarHBondContact O-N 3.02Å
177	V	47	Very low	57.1	Low	123 Å²	123	120.6 Å²	120.6	75%	0.745	66%	0.661	S	S	*	*			trans	-63.1	118.2	173.4	-179.9	0	0	0	0	107.4	G175 S179	G175-V177 PolarHBondContact O-N 3.28Å; V177-S179 PolarHBondContact O-N 3.16Å
178	L	46.4	Very low	55.6	Low	143 Å²	143	124.1 Å²	124.1	75%	0.749	69%	0.691	S	S	*	*			trans	-67.1	98.3	174.3	-171.2	78.7	0	0	0	108.4	K176 N180	K176-L178 PolarHBondContact O-N 3.02Å; L178-N180 WeakPolarHBondContact CD2-OD1 3.29Å; L178-N180 PolarHBondContact O-N 2.83Å
179	S	46.8	Very low	54.2	Low	101 Å²	101	125.4 Å²	125.4	71%	0.706	70%	0.702	S	S	*	*			trans	-72.8	88	173.5	-52.4	0	0	0	0	110	V177 T181	V177-S179 PolarHBondContact O-N 3.16Å; S179-T181 PolarHBondContact O-N 3.33Å; S179-T181 PolarHBondContact O-OG1 3.14Å
180	N	45.2	Very low	52.9	Low	133 Å²	133	125.8 Å²	125.8	71%	0.711	72%	0.717	S	S	*	*			trans	-68.3	104.3	167.9	-79.2	-5	0	0	0	108.8	L178	L178-N180 WeakPolarHBondContact CD2-OD1 3.29Å; L178-N180 PolarHBondContact O-N 2.83Å
181	T	45.8	Very low	51.6	Low	119 Å²	119	124.2 Å²	124.2	73%	0.73	72%	0.719	S	S	*	*			trans	-91.4	104.2	177.7	-47.1	0	0	0	0	108.6	S179	S179-T181 PolarHBondContact O-N 3.33Å; S179-T181 PolarHBondContact O-OG1 3.14Å
182	T	49.4	Very low	50.1	Low	125 Å²	125	127.2 Å²	127.2	77%	0.767	74%	0.735	S	S	*	*			trans	-92.3	110.3	172.2	-35.4	0	0	0	0	109
183	T	42.8	Very low	48.7	Very low	123 Å²	123	128.7 Å²	128.7	76%	0.755	75%	0.747	S	S	*	*			trans	-82.1	118.7	179.4	44.3	0	0	0	0	111.9
184	I	46.6	Very low	47.7	Very low	153 Å²	153	125.1 Å²	125.1	79%	0.785	74%	0.737	S	S	*	*			trans	-137.8	122.5	162.3	-47.1	176.7	0	0	0	108.8
185	P	45.3	Very low	47.1	Very low	112 Å²	112	127.2 Å²	127.2	73%	0.727	75%	0.748	S	S	*	*			trans	-104.6	163.1	174.1	36.9	-28.4	0	0	0	112.6
186	P	55.5	Low	46.8	Very low	119 Å²	119	131 Å²	131	77%	0.773	75%	0.748	S	S	*	*	S	Bend	cis	-129.1	93.5	-11.2	34.8	-14.1	0	0	0	111.3
187	L	47.3	Very low	46.8	Very low	169 Å²	169	128.1 Å²	128.1	89%	0.885	74%	0.743	S	S	*	*	S	Bend	trans	-162.6	116.2	153.7	-149	66.4	0	0	0	109.6
188	A	47.2	Very low	47.3	Very low	84 Å²	84	127.4 Å²	127.4	69%	0.694	73%	0.733	S	S	*	*			trans	59.2	98.9	175.2	0	0	0	0	0	116.2	T190	A188-T190 VanDerWaalsContact C-N 3.31Å; A188-T190 PolarHBondContact O-N 3.11Å
189	I	48.9	Very low	47.9	Very low	162 Å²	162	126.1 Å²	126.1	83%	0.831	73%	0.732	S	S	*	*			trans	-72.7	93.2	157	-58.6	168.2	0	0	0	106.4	V191	I189-V191 HydrophobicContact CG2-CG2 3.79Å; I189-V191 PolarHBondContact O-N 3.45Å
190	T	46.3	Very low	48.8	Very low	117 Å²	117	129.1 Å²	129.1	72%	0.718	73%	0.728	S	S	*	*			trans	-78.7	95.6	166.4	-54.3	0	0	0	0	107.4	A188 M192	A188-T190 VanDerWaalsContact C-N 3.31Å; A188-T190 PolarHBondContact O-N 3.11Å; T190-M192 VanDerWaalsContact C-N 3.34Å; T190-M192 PolarHBondContact O-N 3.05Å
191	V	49.4	Very low	50.1	Low	109 Å²	109	129.2 Å²	129.2	66%	0.661	72%	0.724	S	S	*	*			trans	-71.4	96.1	167.4	-173.5	0	0	0	0	106.9	I189 T193	I189-V191 HydrophobicContact CG2-CG2 3.79Å; I189-V191 PolarHBondContact O-N 3.45Å; V191-T193 VanDerWaalsContact C-N 3.33Å; V191-T193 HydrophobicContact CG1-CG2 3.92Å; V191-T193 PolarHBondContact O-N 3.39Å
192	M	44.8	Very low	51.5	Low	154 Å²	154	128.9 Å²	128.9	76%	0.759	71%	0.71	S	S	*	*			trans	-77.7	89.5	170.4	-144.5	171.8	85.1	0	0	107.3	T190 V194	T190-M192 VanDerWaalsContact C-N 3.34Å; T190-M192 PolarHBondContact O-N 3.05Å; M192-V194 VanDerWaalsContact C-N 3.34Å; M192-V194 HydrophobicContact CE-CG2 4.15Å; M192-V194 PolarHBondContact O-N 2.86Å
193	T	45	Very low	53	Low	108 Å²	108	129 Å²	129	66%	0.663	70%	0.7	S	S	*	*			trans	-71.3	95.2	167.6	51	0	0	0	0	107.6	V191 V195	V191-T193 VanDerWaalsContact C-N 3.33Å; V191-T193 HydrophobicContact CG1-CG2 3.92Å; V191-T193 PolarHBondContact O-N 3.39Å; T193-V195 VanDerWaalsContact C-N 3.3Å; T193-V195 PolarHBondContact O-N 3.2Å
194	V	45.3	Very low	54.8	Low	105 Å²	105	127.1 Å²	127.1	64%	0.636	68%	0.684	S	S	*	*			trans	-65.9	99.2	162.5	-177.1	0	0	0	0	105.6	M192 E196	M192-V194 VanDerWaalsContact C-N 3.34Å; M192-V194 HydrophobicContact CE-CG2 4.15Å; M192-V194 PolarHBondContact O-N 2.86Å; V194-E196 HydrophobicContact CG1-CG 4.03Å; V194-E196 PolarHBondContact O-N 2.87Å
195	V	42.8	Very low	56.5	Low	131 Å²	131	122.7 Å²	122.7	79%	0.794	66%	0.664	S	S	*	*			trans	-73	82	165.7	-177.4	0	0	0	0	105.3	T193 N197	T193-V195 VanDerWaalsContact C-N 3.3Å; T193-V195 PolarHBondContact O-N 3.2Å; V195-N197 PolarHBondContact O-N 3.35Å
196	E	47.4	Very low	58.3	Low	147 Å²	147	119.1 Å²	119.1	69%	0.687	65%	0.648	S	S	*	*			trans	-55.4	133.3	160.1	-84.7	-177.6	161.3	0	0	106.6	V194 I198	V194-E196 HydrophobicContact CG1-CG 4.03Å; V194-E196 PolarHBondContact O-N 2.87Å; E196-I198 HydrophobicContact CB-CG1 4.39Å; E196-I198 WeakPolarHBondContact O-CG1 3.31Å; E196-I198 PolarHBondContact O-N 3.26Å
197	N	46.7	Very low	59.5	Low	153 Å²	153	114.9 Å²	114.9	82%	0.818	62%	0.623	S	S	*	*			trans	-66.8	82.7	169.4	-166.7	16.6	0	0	0	106.5	V195 T199	V195-N197 PolarHBondContact O-N 3.35Å; N197-T199 VanDerWaalsContact C-N 3.28Å; N197-T199 PolarHBondContact O-N 2.84Å
198	I	58.4	Low	61.2	Low	108 Å²	108	110.9 Å²	110.9	55%	0.554	60%	0.596	S	S	*	*			trans	-66.6	94.2	-177.8	-58	174.6	0	0	0	106.3	E196 R200	E196-I198 HydrophobicContact CB-CG1 4.39Å; E196-I198 WeakPolarHBondContact O-CG1 3.31Å; E196-I198 PolarHBondContact O-N 3.26Å; I198-R200 PolarHBondContact O-N 3.04Å
199	T	58.3	Low	62.5	Low	117 Å²	117	108.6 Å²	108.6	72%	0.718	58%	0.576	S	S	*	*			trans	-59.4	110	168.5	-37.1	0	0	0	0	106.1	N197 E201	N197-T199 VanDerWaalsContact C-N 3.28Å; N197-T199 PolarHBondContact O-N 2.84Å; T199-E201 PolarHBondContact O-N 2.67Å; T199-E201 VanDerWaalsContact O-N 3.1Å
200	R	65.9	Low	63.5	Low	163 Å²	163	107.4 Å²	107.4	62%	0.615	57%	0.571	S	S	*	*			trans	-63.9	114.2	179.7	-65.6	179.8	-175	-172.2	3.9	108.5	E171 I198 Y202	E171-R200 VanDerWaalsContact OE1-CD 3.31Å; E171-R200 WeakPolarHBondContact OE1-CD 3.01Å; E171-R200 IonicContact OE1-NE 3.02Å; I198-R200 PolarHBondContact O-N 3.04Å; R200-Y202 HydrophobicContact CB-CD2 4.5Å; R200-Y202 HydrophobicContact CB-CE2 3.73Å; R200-Y202 WeakPolarHBondContact O-CD2 3.47Å
201	E	72.5	Confident	64.3	Low	135 Å²	135	103.1 Å²	103.1	63%	0.631	55%	0.55	S	S	*	*			trans	-83.5	130	175	-69	-167.6	165	0	0	110.1	L172 T199	L172-E201 HydrophobicContact CB-CB 4.33Å; L172-E201 HydrophobicContact CD1-CB 4.09Å; L172-E201 PolarHBondContact N-O 2.62Å; T199-E201 PolarHBondContact O-N 2.67Å; T199-E201 VanDerWaalsContact O-N 3.1Å
202	Y	75.2	Confident	65.1	Low	112 Å²	112	100.6 Å²	100.6	44%	0.439	53%	0.533	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.4	137.2	176.9	-64.9	-88.5	0	0	0	109.9	R169 E171 R200	R169-Y202 HydrophobicContact CB-CD1 4.27Å; E171-Y202 HydrophobicContact CB-CD1 4.16Å; E171-Y202 HydrophobicContact CB-CE1 4.05Å; E171-Y202 HydrophobicContact CG-CE1 4.18Å; R200-Y202 HydrophobicContact CB-CD2 4.5Å; R200-Y202 HydrophobicContact CB-CE2 3.73Å; R200-Y202 WeakPolarHBondContact O-CD2 3.47Å
203	K	82.2	Confident	66.4	Low	127 Å²	127	93.7 Å²	93.7	55%	0.552	50%	0.499	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-105.1	128.7	168.5	-174.4	174.1	-179.3	176.6	0	109.8	K170 L172 V205	K170-K203 PolarHBondContact N-O 3.28Å; K170-K203 PolarHBondContact O-N 3.06Å; L172-K203 HydrophobicContact CD1-CB 4.23Å; L172-K203 HydrophobicContact CD2-CB 4.05Å; L172-K203 HydrophobicContact CD2-CD 4.46Å; L172-K203 HydrophobicContact CG-CB 4.07Å; K203-V205 HydrophobicContact CG-CG2 4.47Å; K203-V205 PolarHBondContact O-N 3.37Å
204	I	79.9	Confident	67.4	Low	84 Å²	84	88.9 Å²	88.9	43%	0.431	47%	0.469	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.8	123.4	170.3	-58.5	177.4	0	0	0	108.1	T167	T167-I204 HydrophobicContact CG2-CG2 3.59Å
205	V	83.3	Confident	68.4	Low	61 Å²	61	84.8 Å²	84.8	37%	0.37	44%	0.443	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.7	123.6	175.2	-174.5	0	0	0	0	108.2	K168 K170 K203	K168-V205 PolarHBondContact N-O 3.16Å; K168-V205 PolarHBondContact O-N 2.91Å; K170-V205 HydrophobicContact CB-CG2 3.93Å; K203-V205 HydrophobicContact CG-CG2 4.47Å; K203-V205 PolarHBondContact O-N 3.37Å
206	G	81.9	Confident	69.9	Low	36 Å²	36	78.5 Å²	78.5	37%	0.371	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-74	134.6	171.6	0	0	0	0	0	111.1	Y165	Y165-G206 VanDerWaalsContact OH-CA 3.29Å; Y165-G206 WeakPolarHBondContact OH-CA 3.38Å
207	A	81.9	Confident	71.3	Confident	31 Å²	31	71.6 Å²	71.6	26%	0.256	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.2	138.2	172.1	0	0	0	0	0	109.9	K166	K166-A207 PolarHBondContact N-O 3.26Å; K166-A207 PolarHBondContact O-N 3.16Å
208	Y	82.8	Confident	72.5	Confident	84 Å²	84	64.7 Å²	64.7	33%	0.329	34%	0.336	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.7	133.4	166.7	-73.8	-80.9	0	0	0	109.2	E155 Q159 Q163 Q164 Y165	E155-Y208 PolarHBondContact OE2-OH 2.93Å; Q159-Y208 VanDerWaalsContact NE2-CD1 3.32Å; Q159-Y208 VanDerWaalsContact NE2-CG 3.33Å; Q163-Y208 HydrophobicContact CB-CD1 4.25Å; Q164-Y208 WeakPolarHBondContact O-CA 3.49Å; Y165-Y208 HydrophobicContact CD2-CD1 4.44Å; Y165-Y208 AromaticContact CD2-CE1 3.96Å; Y165-Y208 HydrophobicContact CD2-CE1 3.96Å; Y165-Y208 HydrophobicContact CD2-CE2 4.17Å; Y165-Y208 AromaticContact CD2-CZ 3.82Å; Y165-Y208 HydrophobicContact CE2-CE2 4.5Å
209	S	73.3	Confident	73.5	Confident	37 Å²	37	61.4 Å²	61.4	26%	0.259	32%	0.321	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.9	145.5	173.8	58.5	0	0	0	0	109.5	Q163 Q164 G211	Q163-S209 WeakPolarHBondContact CA-O 3.29Å; Q164-S209 WeakPolarHBondContact CG-OG 3.47Å; Q164-S209 PolarHBondContact N-O 3.4Å; Q164-S209 PolarHBondContact NE2-OG 2.96Å; Q164-S209 PolarHBondContact O-N 2.84Å; Q164-S209 PolarHBondContact O-OG 2.69Å; S209-G211 PolarHBondContact O-N 3.11Å
210	D	71.1	Confident	74.9	Confident	136 Å²	136	59.7 Å²	59.7	73%	0.727	30%	0.304	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-66	134.2	177.9	-72	-21.4	0	0	0	110.6
211	G	62.7	Low	75.7	Confident	28 Å²	28	52 Å²	52	29%	0.289	28%	0.275	S	S	.	.	S	Bend	trans	145.1	139.7	-174	0	0	0	0	0	111	F162 Q163 Q164 S209 N213	F162-G211 CarbonylContact C-O 3.5Å; F162-G211 CarbonylContact O-C 3.33Å; F162-G211 PolarHBondContact O-N 2.83Å; Q163-G211 CarbonylContact C-O 3.56Å; Q163-G211 WeakPolarHBondContact CA-O 3.49Å; Q163-G211 PolarHBondContact N-O 3.12Å; Q164-G211 PolarHBondContact N-O 3.41Å; S209-G211 PolarHBondContact O-N 3.11Å; G211-N213 PolarHBondContact O-N 3.16Å
212	I	66.2	Low	75.9	Confident	56 Å²	56	47.9 Å²	47.9	29%	0.287	26%	0.259	S	S	.	.			trans	-66.8	125.3	-179.5	-49.5	-172.9	0	0	0	109.4	C161 V214 L217	C161-I212 WeakPolarHBondContact O-CG1 3.25Å; I212-V214 HydrophobicContact CB-CG2 4.07Å; I212-V214 HydrophobicContact CG2-CG2 3.74Å; I212-V214 PolarHBondContact O-N 3.01Å; I212-L217 HydrophobicContact CG2-CD1 3.77Å
213	N	71.4	Confident	76.4	Confident	8 Å²	8	45 Å²	45	4%	0.043	26%	0.259	C	S	.	.			trans	-80.3	74.7	169.3	-179.7	11.1	0	0	0	110.3	N151 A160 Q163 Q164 G211 L215 G216 L217	N151-N213 PolarHBondContact O-ND2 2.98Å; N151-N213 PolarHBondContact O-OD1 3.36Å; A160-N213 HydrophobicContact CB-CB 4.13Å; A160-N213 PolarHBondContact O-N 3.33Å; Q163-N213 WeakPolarHBondContact O-CB 3.43Å; Q164-N213 HydrophobicContact CB-CB 4.23Å; G211-N213 PolarHBondContact O-N 3.16Å; N213-L215 VanDerWaalsContact C-N 3.27Å; N213-L215 PolarHBondContact O-N 3.17Å; N213-G216 PolarHBondContact O-N 3.08Å; N213-G216 PolarHBondContact OD1-N 2.64Å; N213-G216 VanDerWaalsContact OD1-N 3.07Å; N213-L217 WeakPolarHBondContact O-CG 3.45Å; N213-L217 PolarHBondContact O-N 3.16Å
214	V	66.3	Low	76.8	Confident	7 Å²	7	42.2 Å²	42.2	4%	0.042	25%	0.247	C	C	.	.	H	α-helix	trans	-60.7	-36.8	-179.5	174.6	0	0	0	0	111.9	I74 I212 L217 I218 I423	I74-V214 HydrophobicContact CD1-CG1 3.65Å; I74-V214 HydrophobicContact CD1-CG2 4.41Å; I212-V214 HydrophobicContact CB-CG2 4.07Å; I212-V214 HydrophobicContact CG2-CG2 3.74Å; I212-V214 PolarHBondContact O-N 3.01Å; V214-L217 PolarHBondContact O-N 3.45Å; V214-I218 HydrophobicContact CG1-CD1 3.72Å; V214-I218 HydrophobicContact CG1-CG1 4.24Å; V214-I218 VanDerWaalsContact O-CG1 3.29Å; V214-I218 WeakPolarHBondContact O-CG1 3.39Å; V214-I218 PolarHBondContact O-N 3.32Å; V214-I423 HydrophobicContact CB-CD1 3.42Å; V214-I423 VanDerWaalsContact CB-CD1 3.42Å; V214-I423 HydrophobicContact CB-CG1 4.04Å; V214-I423 HydrophobicContact CG1-CD1 3.46Å; V214-I423 VanDerWaalsContact CG1-CD1 3.46Å; V214-I423 HydrophobicContact CG2-CD1 3.94Å; V214-I423 HydrophobicContact CG2-CG1 4.29Å
215	L	65.6	Low	76.9	Confident	19 Å²	19	38.2 Å²	38.2	10%	0.099	23%	0.226	C	C	.	.	H	α-helix	trans	-58.9	-50.4	179.1	177.7	60.7	0	0	0	111.9	L148 N151 M152 N213 L217 I218 V219 V405	L148-L215 HydrophobicContact CD2-CD2 4.35Å; L148-L215 HydrophobicContact CG-CD2 4.02Å; N151-L215 HydrophobicContact CB-CD2 4.43Å; M152-L215 HydrophobicContact CG-CD1 4.14Å; M152-L215 HydrophobicContact CG-CD2 3.72Å; M152-L215 HydrophobicContact CG-CG 3.84Å; N213-L215 VanDerWaalsContact C-N 3.27Å; N213-L215 PolarHBondContact O-N 3.17Å; L215-L217 VanDerWaalsContact C-N 3.32Å; L215-L217 PolarHBondContact O-N 3.2Å; L215-I218 PolarHBondContact O-N 3.45Å; L215-V219 WeakPolarHBondContact O-CG2 3.17Å; L215-V219 PolarHBondContact O-N 3.31Å; L215-V219 VanDerWaalsContact O-N 3.09Å; L215-V405 HydrophobicContact CD1-CB 4.22Å; L215-V405 HydrophobicContact CD1-CG1 3.27Å
216	G	75.1	Confident	76.8	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-63.1	-38.2	177.4	0	0	0	0	0	112.9	N151 N213 V219 F220	N151-G216 WeakPolarHBondContact O-CA 3.28Å; N151-G216 PolarHBondContact O-N 2.86Å; N213-G216 PolarHBondContact O-N 3.08Å; N213-G216 PolarHBondContact OD1-N 2.64Å; N213-G216 VanDerWaalsContact OD1-N 3.07Å; G216-V219 PolarHBondContact O-N 2.73Å; G216-F220 WeakPolarHBondContact O-CB 3.44Å; G216-F220 PolarHBondContact O-N 3.44Å
217	L	77.3	Confident	77.2	Confident	2 Å²	2	41 Å²	41	1%	0.01	23%	0.233	C	C	.	.	H	α-helix	trans	-62.9	-42.9	175.7	-67.6	172.3	0	0	0	111.9	L71 L157 A160 I212 N213 V214 L215 F220 C221	L71-L217 HydrophobicContact CD1-CD1 3.49Å; L71-L217 VanDerWaalsContact CD1-CD1 3.49Å; L157-L217 HydrophobicContact CD1-CD2 3.75Å; A160-L217 HydrophobicContact CB-CD2 4.3Å; A160-L217 HydrophobicContact CB-CG 4.48Å; I212-L217 HydrophobicContact CG2-CD1 3.77Å; N213-L217 WeakPolarHBondContact O-CG 3.45Å; N213-L217 PolarHBondContact O-N 3.16Å; V214-L217 PolarHBondContact O-N 3.45Å; L215-L217 VanDerWaalsContact C-N 3.32Å; L215-L217 PolarHBondContact O-N 3.2Å; L217-F220 PolarHBondContact O-N 3.2Å; L217-C221 VanDerWaalsContact O-CB 3.31Å; L217-C221 WeakPolarHBondContact O-CB 3.41Å; L217-C221 PolarHBondContact O-N 3.08Å; L217-C221 PolarHBondContact O-SG 3.21Å
218	I	72.4	Confident	77.5	Confident	7 Å²	7	39.7 Å²	39.7	4%	0.036	22%	0.221	C	C	.	.	H	α-helix	trans	-62.8	-51.2	177.3	-67.1	159.7	0	0	0	110.4	I74 V214 L215 F220 C221 V222	I74-I218 HydrophobicContact CG2-CG1 4.09Å; V214-I218 HydrophobicContact CG1-CD1 3.72Å; V214-I218 HydrophobicContact CG1-CG1 4.24Å; V214-I218 VanDerWaalsContact O-CG1 3.29Å; V214-I218 WeakPolarHBondContact O-CG1 3.39Å; V214-I218 PolarHBondContact O-N 3.32Å; L215-I218 PolarHBondContact O-N 3.45Å; I218-F220 VanDerWaalsContact C-N 3.27Å; I218-F220 PolarHBondContact O-N 3.35Å; I218-C221 PolarHBondContact O-N 3.13Å; I218-C221 VanDerWaalsContact O-N 3.12Å; I218-V222 HydrophobicContact CG2-CG2 4.11Å; I218-V222 VanDerWaalsContact O-CG2 3.28Å; I218-V222 WeakPolarHBondContact O-CG2 3.35Å; I218-V222 PolarHBondContact O-N 3.1Å
219	V	78.4	Confident	77.4	Confident	39 Å²	39	36.7 Å²	36.7	24%	0.236	22%	0.216	C	C	.	.	H	α-helix	trans	-56.9	-44.6	-179.3	172.9	0	0	0	0	110.6	M152 F153 L215 G216 A223	M152-V219 HydrophobicContact CB-CG2 4.19Å; M152-V219 HydrophobicContact CE-CG2 3.99Å; M152-V219 HydrophobicContact CG-CG2 4.23Å; F153-V219 HydrophobicContact CE1-CG1 4.38Å; L215-V219 WeakPolarHBondContact O-CG2 3.17Å; L215-V219 PolarHBondContact O-N 3.31Å; L215-V219 VanDerWaalsContact O-N 3.09Å; G216-V219 PolarHBondContact O-N 2.73Å; V219-A223 WeakPolarHBondContact O-CB 3.34Å; V219-A223 PolarHBondContact O-N 2.94Å; V219-A223 VanDerWaalsContact O-N 3.11Å
220	F	88.4	Confident	77.9	Confident	82 Å²	82	42.3 Å²	42.3	36%	0.36	24%	0.235	S	C	.	.	H	α-helix	trans	-61.3	-50.2	174.4	174.5	-96	0	0	0	112.3	L157 G216 L217 I218 V222 A223 F224	L157-F220 HydrophobicContact CD1-CB 4.13Å; L157-F220 HydrophobicContact CD1-CD1 3.7Å; L157-F220 HydrophobicContact CD1-CD2 4.27Å; L157-F220 HydrophobicContact CD1-CE1 4.2Å; L157-F220 HydrophobicContact CD1-CG 3.75Å; L157-F220 HydrophobicContact CD2-CD1 3.93Å; L157-F220 HydrophobicContact CD2-CE1 3.52Å; L157-F220 HydrophobicContact CD2-CE2 4.17Å; L157-F220 HydrophobicContact CD2-CG 4.41Å; L157-F220 HydrophobicContact CD2-CZ 3.66Å; L157-F220 HydrophobicContact CG-CD1 4.5Å; G216-F220 WeakPolarHBondContact O-CB 3.44Å; G216-F220 PolarHBondContact O-N 3.44Å; L217-F220 PolarHBondContact O-N 3.2Å; I218-F220 VanDerWaalsContact C-N 3.27Å; I218-F220 PolarHBondContact O-N 3.35Å; F220-V222 VanDerWaalsContact C-N 3.34Å; F220-V222 PolarHBondContact O-N 3.07Å; F220-A223 PolarHBondContact O-N 2.89Å; F220-F224 HydrophobicContact CE1-CB 4.24Å; F220-F224 HydrophobicContact CE1-CG 4.33Å; F220-F224 HydrophobicContact CZ-CB 4.28Å; F220-F224 HydrophobicContact CZ-CD2 4.32Å; F220-F224 HydrophobicContact CZ-CG 4.22Å; F220-F224 WeakPolarHBondContact O-CB 3.49Å; F220-F224 PolarHBondContact O-N 2.77Å
221	C	82.3	Confident	78.6	Confident	1 Å²	1	40.2 Å²	40.2	1%	0.007	22%	0.222	C	C	.	.	H	α-helix	trans	-64.1	-37	-177	-69.9	0	0	0	0	112.7	M78 I79 L217 I218 G225	M78-C221 HydrophobicContact CB-CB 3.75Å; I79-C221 HydrophobicContact CG1-CB 3.85Å; L217-C221 VanDerWaalsContact O-CB 3.31Å; L217-C221 WeakPolarHBondContact O-CB 3.41Å; L217-C221 PolarHBondContact O-N 3.08Å; L217-C221 PolarHBondContact O-SG 3.21Å; I218-C221 PolarHBondContact O-N 3.13Å; I218-C221 VanDerWaalsContact O-N 3.12Å; C221-G225 PolarHBondContact O-N 3.19Å
222	V	77.2	Confident	79.5	Confident	48 Å²	48	41 Å²	41	29%	0.291	23%	0.231	S	C	.	.	H	α-helix	trans	-64.1	-51.1	174.2	171.7	0	0	0	0	110	V82 I218 F220 F224 G225 L226	V82-V222 HydrophobicContact CG1-CG1 4.28Å; V82-V222 HydrophobicContact CG2-CB 4.45Å; V82-V222 HydrophobicContact CG2-CG1 4.33Å; V82-V222 HydrophobicContact CG2-CG2 4.13Å; I218-V222 HydrophobicContact CG2-CG2 4.11Å; I218-V222 VanDerWaalsContact O-CG2 3.28Å; I218-V222 WeakPolarHBondContact O-CG2 3.35Å; I218-V222 PolarHBondContact O-N 3.1Å; F220-V222 VanDerWaalsContact C-N 3.34Å; F220-V222 PolarHBondContact O-N 3.07Å; V222-F224 VanDerWaalsContact C-N 3.33Å; V222-F224 PolarHBondContact O-N 2.96Å; V222-G225 PolarHBondContact O-N 3.32Å; V222-L226 HydrophobicContact CG1-CD1 4.46Å; V222-L226 WeakPolarHBondContact O-CG 3.45Å; V222-L226 PolarHBondContact O-N 3.08Å
223	A	85.3	Confident	80.5	Confident	53 Å²	53	45.4 Å²	45.4	44%	0.438	26%	0.255	S	S	.	.	H	α-helix	trans	-60.7	-44.1	178.5	0	0	0	0	0	111.7	V219 F220 L226 V227	V219-A223 WeakPolarHBondContact O-CB 3.34Å; V219-A223 PolarHBondContact O-N 2.94Å; V219-A223 VanDerWaalsContact O-N 3.11Å; F220-A223 PolarHBondContact O-N 2.89Å; A223-L226 PolarHBondContact O-N 3.18Å; A223-V227 WeakPolarHBondContact O-CG2 3.21Å; A223-V227 PolarHBondContact O-N 2.76Å
224	F	89.4	Confident	81.3	Confident	68 Å²	68	53.2 Å²	53.2	30%	0.298	29%	0.289	S	S	.	.	H	α-helix	trans	-67.4	-41.5	179.7	-171.8	-115.6	0	0	0	112.4	I79 F220 V222 L226 V227 I228 F242	I79-F224 HydrophobicContact CD1-CD1 3.73Å; I79-F224 HydrophobicContact CD1-CE1 4.2Å; I79-F224 HydrophobicContact CG1-CD1 4.12Å; I79-F224 HydrophobicContact CG2-CD1 4.42Å; F220-F224 HydrophobicContact CE1-CB 4.24Å; F220-F224 HydrophobicContact CE1-CG 4.33Å; F220-F224 HydrophobicContact CZ-CB 4.28Å; F220-F224 HydrophobicContact CZ-CD2 4.32Å; F220-F224 HydrophobicContact CZ-CG 4.22Å; F220-F224 WeakPolarHBondContact O-CB 3.49Å; F220-F224 PolarHBondContact O-N 2.77Å; V222-F224 VanDerWaalsContact C-N 3.33Å; V222-F224 PolarHBondContact O-N 2.96Å; F224-L226 PolarHBondContact O-N 3.35Å; F224-V227 PolarHBondContact O-N 2.73Å; F224-I228 HydrophobicContact CD1-CD1 3.55Å; F224-I228 HydrophobicContact CD1-CG1 4.45Å; F224-I228 HydrophobicContact CE1-CD1 3.2Å; F224-I228 HydrophobicContact CE1-CG1 4.22Å; F224-I228 HydrophobicContact CE2-CD1 4.25Å; F224-I228 HydrophobicContact CE2-CG1 4.46Å; F224-I228 HydrophobicContact CG-CD1 4.24Å; F224-I228 HydrophobicContact CZ-CD1 3.58Å; F224-I228 HydrophobicContact CZ-CG1 4.21Å; F224-I228 WeakPolarHBondContact O-CG1 3.36Å; F224-I228 PolarHBondContact O-N 3.21Å; F224-F242 AromaticContact CE1-CE2 3.88Å; F224-F242 HydrophobicContact CE1-CE2 3.88Å; F224-F242 HydrophobicContact CE1-CZ 4.2Å
225	G	82.9	Confident	82.3	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-60.2	-43.4	173.4	0	0	0	0	0	112.4	A83 C221 V222 V227 I228 G229	A83-G225 WeakPolarHBondContact CA-O 3.4Å; A83-G225 VanDerWaalsContact CB-O 3.27Å; A83-G225 WeakPolarHBondContact CB-O 3.43Å; C221-G225 PolarHBondContact O-N 3.19Å; V222-G225 PolarHBondContact O-N 3.32Å; G225-V227 VanDerWaalsContact C-N 3.33Å; G225-V227 PolarHBondContact O-N 3Å; G225-I228 PolarHBondContact O-N 3.07Å; G225-G229 PolarHBondContact O-N 3.42Å
226	L	81.7	Confident	83.3	Confident	75 Å²	75	57.7 Å²	57.7	39%	0.393	30%	0.304	S	S	.	.	H	α-helix	trans	-61.8	-40	174.1	-70.8	175	0	0	0	112.4	V82 V222 A223 F224 K230	V82-L226 HydrophobicContact CG1-CB 4.43Å; V82-L226 HydrophobicContact CG1-CD1 4.49Å; V82-L226 HydrophobicContact CG1-CD2 3.46Å; V82-L226 VanDerWaalsContact CG1-CD2 3.46Å; V82-L226 HydrophobicContact CG1-CG 3.46Å; V82-L226 VanDerWaalsContact CG1-CG 3.46Å; V222-L226 HydrophobicContact CG1-CD1 4.46Å; V222-L226 WeakPolarHBondContact O-CG 3.45Å; V222-L226 PolarHBondContact O-N 3.08Å; A223-L226 PolarHBondContact O-N 3.18Å; F224-L226 PolarHBondContact O-N 3.35Å; L226-K230 WeakPolarHBondContact O-CG 3.4Å; L226-K230 PolarHBondContact O-N 2.91Å
227	V	89.3	Confident	84.2	Confident	81 Å²	81	63.8 Å²	63.8	49%	0.491	34%	0.335	S	S	.	.	H	α-helix	trans	-66.8	-46.5	177.5	172.1	0	0	0	0	110.7	A223 F224 G225 G229 K230 M231	A223-V227 WeakPolarHBondContact O-CG2 3.21Å; A223-V227 PolarHBondContact O-N 2.76Å; F224-V227 PolarHBondContact O-N 2.73Å; G225-V227 VanDerWaalsContact C-N 3.33Å; G225-V227 PolarHBondContact O-N 3Å; V227-G229 VanDerWaalsContact C-N 3.32Å; V227-G229 PolarHBondContact O-N 3.35Å; V227-K230 PolarHBondContact O-N 2.65Å; V227-K230 VanDerWaalsContact O-N 3.13Å; V227-M231 HydrophobicContact CG1-CG 4.42Å; V227-M231 HydrophobicContact CG1-SD 4.04Å; V227-M231 VanDerWaalsContact O-CG 3.28Å; V227-M231 WeakPolarHBondContact O-CG 3.47Å; V227-M231 PolarHBondContact O-N 3.44Å; V227-M231 VanDerWaalsContact O-N 3.13Å
228	I	87.9	Confident	85	Confident	3 Å²	3	66.6 Å²	66.6	2%	0.015	35%	0.35	C	S	.	.	H	α-helix	trans	-60	-42.7	177.7	-70.9	170.4	0	0	0	111.2	I79 F224 G225 K230 M231 G235 L238 L239 F242	I79-I228 HydrophobicContact CG2-CD1 3.98Å; F224-I228 HydrophobicContact CD1-CD1 3.55Å; F224-I228 HydrophobicContact CD1-CG1 4.45Å; F224-I228 HydrophobicContact CE1-CD1 3.2Å; F224-I228 HydrophobicContact CE1-CG1 4.22Å; F224-I228 HydrophobicContact CE2-CD1 4.25Å; F224-I228 HydrophobicContact CE2-CG1 4.46Å; F224-I228 HydrophobicContact CG-CD1 4.24Å; F224-I228 HydrophobicContact CZ-CD1 3.58Å; F224-I228 HydrophobicContact CZ-CG1 4.21Å; F224-I228 WeakPolarHBondContact O-CG1 3.36Å; F224-I228 PolarHBondContact O-N 3.21Å; G225-I228 PolarHBondContact O-N 3.07Å; I228-K230 VanDerWaalsContact C-N 3.26Å; I228-K230 PolarHBondContact O-N 2.95Å; I228-M231 PolarHBondContact O-N 2.92Å; I228-M231 VanDerWaalsContact O-N 3.15Å; I228-G235 VanDerWaalsContact CG2-O 3.3Å; I228-G235 WeakPolarHBondContact CG2-O 3.49Å; I228-L238 HydrophobicContact CD1-CB 3.94Å; I228-L238 HydrophobicContact CD1-CD1 4.01Å; I228-L238 HydrophobicContact CG1-CB 4.46Å; I228-L238 HydrophobicContact CG1-CD1 4.07Å; I228-L238 HydrophobicContact CG2-CB 4.29Å; I228-L239 HydrophobicContact CG2-CB 4.4Å; I228-F242 HydrophobicContact CD1-CE2 4.41Å
229	G	80.8	Confident	85.5	Confident	20 Å²	20	69 Å²	69	21%	0.206	36%	0.362	C	S	.	.	H	α-helix	trans	-57.2	-40.6	175.9	0	0	0	0	0	112.4	G225 V227 M231	G225-G229 PolarHBondContact O-N 3.42Å; V227-G229 VanDerWaalsContact C-N 3.32Å; V227-G229 PolarHBondContact O-N 3.35Å; G229-M231 VanDerWaalsContact C-N 3.33Å; G229-M231 PolarHBondContact O-N 2.97Å
230	K	83.9	Confident	86	Confident	155 Å²	155	71.8 Å²	71.8	67%	0.674	37%	0.373	S	S	*	.	H	α-helix	trans	-75	-16.2	178.6	-74.4	-179.5	178.3	-171.5	0	115	D86 L226 V227 I228 G232	D86-K230 WeakPolarHBondContact OD2-CG 3.19Å; L226-K230 WeakPolarHBondContact O-CG 3.4Å; L226-K230 PolarHBondContact O-N 2.91Å; V227-K230 PolarHBondContact O-N 2.65Å; V227-K230 VanDerWaalsContact O-N 3.13Å; I228-K230 VanDerWaalsContact C-N 3.26Å; I228-K230 PolarHBondContact O-N 2.95Å; K230-G232 PolarHBondContact O-N 3.2Å
231	M	85.9	Confident	86.3	Confident	92 Å²	92	73.6 Å²	73.6	45%	0.453	38%	0.381	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.9	-3.2	-177.7	-74.8	173.5	72.2	0	0	113.5	V227 I228 G229 D233 K234	V227-M231 HydrophobicContact CG1-CG 4.42Å; V227-M231 HydrophobicContact CG1-SD 4.04Å; V227-M231 VanDerWaalsContact O-CG 3.28Å; V227-M231 WeakPolarHBondContact O-CG 3.47Å; V227-M231 PolarHBondContact O-N 3.44Å; V227-M231 VanDerWaalsContact O-N 3.13Å; I228-M231 PolarHBondContact O-N 2.92Å; I228-M231 VanDerWaalsContact O-N 3.15Å; G229-M231 VanDerWaalsContact C-N 3.33Å; G229-M231 PolarHBondContact O-N 2.97Å; M231-D233 PolarHBondContact O-N 3.07Å; M231-K234 HydrophobicContact CE-CB 4.44Å; M231-K234 PolarHBondContact O-N 3.26Å
232	G	82.6	Confident	86.5	Confident	46 Å²	46	74.7 Å²	74.7	47%	0.474	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	58.9	-132.7	-179.9	0	0	0	0	0	111.9	K230 K234 G235 R236	K230-G232 PolarHBondContact O-N 3.2Å; G232-K234 VanDerWaalsContact C-N 3.26Å; G232-K234 PolarHBondContact O-N 3.16Å; G232-G235 PolarHBondContact O-N 2.98Å; G232-R236 PolarHBondContact O-N 2.97Å
233	D	85.6	Confident	86.6	Confident	147 Å²	147	76.5 Å²	76.5	79%	0.786	39%	0.393	S	S	*	.	H	α-helix	trans	-60	-32.7	-175.1	-63	-40	0	0	0	113.7	M231 G235 R236	M231-D233 PolarHBondContact O-N 3.07Å; D233-G235 VanDerWaalsContact C-N 3.29Å; D233-G235 PolarHBondContact O-N 3.12Å; D233-R236 WeakPolarHBondContact O-CB 3.3Å; D233-R236 PolarHBondContact O-N 3.35Å
234	K	89	Confident	86.7	Confident	172 Å²	172	76.8 Å²	76.8	75%	0.748	40%	0.396	S	S	*	.	H	α-helix	trans	-68.1	-31.2	176.8	-67.6	-175.8	-179.6	178.1	0	112.2	M231 G232	M231-K234 HydrophobicContact CE-CB 4.44Å; M231-K234 PolarHBondContact O-N 3.26Å; G232-K234 VanDerWaalsContact C-N 3.26Å; G232-K234 PolarHBondContact O-N 3.16Å
235	G	87.4	Confident	86.5	Confident	1 Å²	1	76.2 Å²	76.2	1%	0.01	40%	0.396	C	S	.	.	H	α-helix	trans	-76.3	-23.6	178	0	0	0	0	0	113.3	I228 G232 D233 I237 L238 L239	I228-G235 VanDerWaalsContact CG2-O 3.3Å; I228-G235 WeakPolarHBondContact CG2-O 3.49Å; G232-G235 PolarHBondContact O-N 2.98Å; D233-G235 VanDerWaalsContact C-N 3.29Å; D233-G235 PolarHBondContact O-N 3.12Å; G235-I237 VanDerWaalsContact C-N 3.32Å; G235-I237 PolarHBondContact O-N 3.41Å; G235-L238 PolarHBondContact O-N 3.15Å; G235-L238 VanDerWaalsContact O-N 3.12Å; G235-L239 PolarHBondContact O-N 3.13Å
236	R	86.9	Confident	86.2	Confident	120 Å²	120	77.7 Å²	77.7	45%	0.453	40%	0.403	S	S	.	.	H	α-helix	trans	-57.1	-40.7	-175.1	-173.8	174.5	173	173.6	0.2	113.5	G232 D233 L238 L239 E240	G232-R236 PolarHBondContact O-N 2.97Å; D233-R236 WeakPolarHBondContact O-CB 3.3Å; D233-R236 PolarHBondContact O-N 3.35Å; R236-L238 VanDerWaalsContact C-N 3.28Å; R236-L238 PolarHBondContact O-N 3.34Å; R236-L239 PolarHBondContact O-N 3.44Å; R236-E240 HydrophobicContact CG-CG 4.39Å; R236-E240 WeakPolarHBondContact CG-OE1 3.39Å; R236-E240 IonicContact CZ-OE1 3.2Å; R236-E240 IonicContact NE-OE1 3.46Å; R236-E240 PolarHBondContact NE-OE1 3.31Å; R236-E240 IonicContact NH2-OE1 3.47Å; R236-E240 PolarHBondContact NH2-OE1 2.9Å; R236-E240 WeakPolarHBondContact O-CG 3.38Å; R236-E240 PolarHBondContact O-N 2.64Å
237	I	93.8	Very high	85.8	Confident	128 Å²	128	79.1 Å²	79.1	66%	0.656	41%	0.408	S	S	*	.	H	α-helix	trans	-63.9	-36.1	-178.9	-143.4	166.5	0	0	0	112	G235 F241	G235-I237 VanDerWaalsContact C-N 3.32Å; G235-I237 PolarHBondContact O-N 3.41Å; I237-F241 WeakPolarHBondContact O-CB 3.24Å; I237-F241 PolarHBondContact O-N 3.46Å; I237-F241 VanDerWaalsContact O-N 3.11Å
238	L	92.8	Very high	85.4	Confident	61 Å²	61	77.7 Å²	77.7	32%	0.319	41%	0.405	S	S	.	.	H	α-helix	trans	-72.9	-40.7	177.1	-68.4	174.7	0	0	0	110.5	I228 G235 R236 F241 F242	I228-L238 HydrophobicContact CD1-CB 3.94Å; I228-L238 HydrophobicContact CD1-CD1 4.01Å; I228-L238 HydrophobicContact CG1-CB 4.46Å; I228-L238 HydrophobicContact CG1-CD1 4.07Å; I228-L238 HydrophobicContact CG2-CB 4.29Å; G235-L238 PolarHBondContact O-N 3.15Å; G235-L238 VanDerWaalsContact O-N 3.12Å; R236-L238 VanDerWaalsContact C-N 3.28Å; R236-L238 PolarHBondContact O-N 3.34Å; L238-F241 WeakPolarHBondContact O-CB 3.35Å; L238-F241 PolarHBondContact O-N 3.41Å; L238-F242 WeakPolarHBondContact O-CD2 3.45Å; L238-F242 PolarHBondContact O-N 2.95Å
239	L	84.5	Confident	84.7	Confident	57 Å²	57	77.8 Å²	77.8	30%	0.298	41%	0.405	S	S	.	.	H	α-helix	trans	-60.4	-47.8	176.8	-170.4	126.7	0	0	0	111.6	A83 I228 G235 R236 F241 F242 D243	A83-L239 HydrophobicContact CB-CD1 3.39Å; I228-L239 HydrophobicContact CG2-CB 4.4Å; G235-L239 PolarHBondContact O-N 3.13Å; R236-L239 PolarHBondContact O-N 3.44Å; L239-F241 VanDerWaalsContact C-N 3.32Å; L239-F241 PolarHBondContact O-N 2.93Å; L239-F242 PolarHBondContact O-N 3.13Å; L239-D243 WeakPolarHBondContact O-CB 3.28Å; L239-D243 PolarHBondContact O-N 3.44Å
240	E	88.2	Confident	84	Confident	97 Å²	97	78.7 Å²	78.7	45%	0.453	41%	0.405	S	S	.	.	H	α-helix	trans	-62.7	-38.2	177	-71.6	176.5	-174.7	0	0	111.8	R236 D243 A244	R236-E240 HydrophobicContact CG-CG 4.39Å; R236-E240 WeakPolarHBondContact CG-OE1 3.39Å; R236-E240 IonicContact CZ-OE1 3.2Å; R236-E240 IonicContact NE-OE1 3.46Å; R236-E240 PolarHBondContact NE-OE1 3.31Å; R236-E240 IonicContact NH2-OE1 3.47Å; R236-E240 PolarHBondContact NH2-OE1 2.9Å; R236-E240 WeakPolarHBondContact O-CG 3.38Å; R236-E240 PolarHBondContact O-N 2.64Å; E240-D243 PolarHBondContact O-N 2.93Å; E240-A244 WeakPolarHBondContact O-CB 3.41Å; E240-A244 PolarHBondContact O-N 3.25Å
241	F	94.3	Very high	83.6	Confident	120 Å²	120	76.6 Å²	76.6	53%	0.526	40%	0.396	S	S	.	.	H	α-helix	trans	-61.2	-50.3	173.6	169.4	-96	0	0	0	112.4	I237 L238 L239 D243 A244 L245	I237-F241 WeakPolarHBondContact O-CB 3.24Å; I237-F241 PolarHBondContact O-N 3.46Å; I237-F241 VanDerWaalsContact O-N 3.11Å; L238-F241 WeakPolarHBondContact O-CB 3.35Å; L238-F241 PolarHBondContact O-N 3.41Å; L239-F241 VanDerWaalsContact C-N 3.32Å; L239-F241 PolarHBondContact O-N 2.93Å; F241-D243 VanDerWaalsContact C-N 3.31Å; F241-D243 PolarHBondContact O-N 3.25Å; F241-A244 PolarHBondContact O-N 2.96Å; F241-L245 HydrophobicContact CE1-CD2 4.4Å; F241-L245 WeakPolarHBondContact O-CB 3.15Å; F241-L245 PolarHBondContact O-N 2.84Å
242	F	86.8	Confident	83.1	Confident	24 Å²	24	76.7 Å²	76.7	11%	0.105	40%	0.397	C	S	.	.	H	α-helix	trans	-68.1	-31.8	-179.5	-76.8	-68.1	0	0	0	112.2	I75 S76 I79 T80 F224 I228 L238 L239 L245 N246	I75-F242 HydrophobicContact CG2-CD1 4.47Å; I75-F242 HydrophobicContact CG2-CE1 3.89Å; S76-F242 WeakPolarHBondContact CB-O 3.49Å; I79-F242 HydrophobicContact CB-CD2 4.4Å; I79-F242 HydrophobicContact CB-CG 4.33Å; I79-F242 HydrophobicContact CD1-CD1 3.95Å; I79-F242 HydrophobicContact CD1-CD2 4.16Å; I79-F242 HydrophobicContact CD1-CE1 3.61Å; I79-F242 HydrophobicContact CD1-CE2 3.87Å; I79-F242 HydrophobicContact CD1-CG 4.23Å; I79-F242 HydrophobicContact CD1-CZ 3.57Å; I79-F242 HydrophobicContact CG2-CB 4.38Å; I79-F242 HydrophobicContact CG2-CD2 3.69Å; I79-F242 HydrophobicContact CG2-CE2 4.18Å; I79-F242 HydrophobicContact CG2-CG 4.05Å; T80-F242 HydrophobicContact CG2-CB 3.67Å; F224-F242 AromaticContact CE1-CE2 3.88Å; F224-F242 HydrophobicContact CE1-CE2 3.88Å; F224-F242 HydrophobicContact CE1-CZ 4.2Å; I228-F242 HydrophobicContact CD1-CE2 4.41Å; L238-F242 WeakPolarHBondContact O-CD2 3.45Å; L238-F242 PolarHBondContact O-N 2.95Å; L239-F242 PolarHBondContact O-N 3.13Å; F242-L245 HydrophobicContact CD1-CD2 4.35Å; F242-L245 PolarHBondContact O-N 3.43Å; F242-N246 WeakPolarHBondContact O-CB 3.37Å; F242-N246 PolarHBondContact O-N 3.32Å
243	D	80.5	Confident	82.3	Confident	86 Å²	86	74.9 Å²	74.9	46%	0.46	38%	0.377	S	S	.	.	H	α-helix	trans	-67.4	-45.3	175.2	-165.6	48.5	0	0	0	111.8	T80 L239 E240 F241 L245 N246 E247	T80-D243 HydrophobicContact CG2-CB 4Å; L239-D243 WeakPolarHBondContact O-CB 3.28Å; L239-D243 PolarHBondContact O-N 3.44Å; E240-D243 PolarHBondContact O-N 2.93Å; F241-D243 VanDerWaalsContact C-N 3.31Å; F241-D243 PolarHBondContact O-N 3.25Å; D243-L245 VanDerWaalsContact C-N 3.32Å; D243-L245 PolarHBondContact O-N 3.07Å; D243-N246 WeakPolarHBondContact O-CB 3.43Å; D243-N246 PolarHBondContact O-N 3.33Å; D243-N246 VanDerWaalsContact O-N 3.16Å; D243-E247 PolarHBondContact O-N 2.75Å
244	A	85.6	Confident	81.4	Confident	59 Å²	59	73.8 Å²	73.8	49%	0.488	37%	0.367	S	S	.	.	H	α-helix	trans	-61	-40.3	173.8	0	0	0	0	0	112.3	E240 F241 N246 E247 A248	E240-A244 WeakPolarHBondContact O-CB 3.41Å; E240-A244 PolarHBondContact O-N 3.25Å; F241-A244 PolarHBondContact O-N 2.96Å; A244-N246 VanDerWaalsContact C-N 3.35Å; A244-E247 PolarHBondContact O-N 3.02Å; A244-A248 WeakPolarHBondContact O-CB 3.45Å; A244-A248 PolarHBondContact O-N 3.49Å
245	L	86.6	Confident	81	Confident	57 Å²	57	70.9 Å²	70.9	30%	0.298	36%	0.359	S	S	.	.	H	α-helix	trans	-63.3	-40.8	175.1	-179.4	61.1	0	0	0	111.8	F241 F242 D243 A248 T249	F241-L245 HydrophobicContact CE1-CD2 4.4Å; F241-L245 WeakPolarHBondContact O-CB 3.15Å; F241-L245 PolarHBondContact O-N 2.84Å; F242-L245 HydrophobicContact CD1-CD2 4.35Å; F242-L245 PolarHBondContact O-N 3.43Å; D243-L245 VanDerWaalsContact C-N 3.32Å; D243-L245 PolarHBondContact O-N 3.07Å; L245-A248 PolarHBondContact O-N 3.02Å; L245-T249 WeakPolarHBondContact O-CB 3.15Å; L245-T249 PolarHBondContact O-N 3.17Å; L245-T249 PolarHBondContact O-OG1 3.47Å
246	N	75.5	Confident	80.3	Confident	30 Å²	30	71.3 Å²	71.3	16%	0.16	36%	0.361	C	S	.	.	H	α-helix	trans	-62.3	-49.1	176.7	-173.2	39.7	0	0	0	111	L73 S76 S77 F242 D243 A244 A248 T249 M250	L73-N246 WeakPolarHBondContact CD1-OD1 2.92Å; S76-N246 WeakPolarHBondContact OG-CA 3.27Å; S77-N246 PolarHBondContact OG-OD1 3.34Å; F242-N246 WeakPolarHBondContact O-CB 3.37Å; F242-N246 PolarHBondContact O-N 3.32Å; D243-N246 WeakPolarHBondContact O-CB 3.43Å; D243-N246 PolarHBondContact O-N 3.33Å; D243-N246 VanDerWaalsContact O-N 3.16Å; A244-N246 VanDerWaalsContact C-N 3.35Å; N246-A248 PolarHBondContact O-N 3.48Å; N246-T249 PolarHBondContact O-N 2.78Å; N246-M250 WeakPolarHBondContact O-CG 3.3Å; N246-M250 PolarHBondContact O-N 2.77Å
247	E	74.3	Confident	79.4	Confident	106 Å²	106	66.4 Å²	66.4	50%	0.495	34%	0.343	S	S	.	.	H	α-helix	trans	-62.2	-42.7	178.8	-162.8	-166.8	142.4	0	0	112	D243 A244 T249 M250 K251	D243-E247 PolarHBondContact O-N 2.75Å; A244-E247 PolarHBondContact O-N 3.02Å; E247-T249 VanDerWaalsContact C-N 3.33Å; E247-T249 PolarHBondContact O-N 3.24Å; E247-M250 PolarHBondContact O-N 3.34Å; E247-K251 PolarHBondContact O-N 2.83Å; E247-K251 VanDerWaalsContact O-N 3.13Å; E247-K251 WeakPolarHBondContact OE1-CE 3.36Å; E247-K251 IonicContact OE1-NZ 2.94Å; E247-K251 PolarHBondContact OE1-NZ 3.46Å
248	A	81	Confident	78.6	Confident	51 Å²	51	64.1 Å²	64.1	42%	0.421	34%	0.338	S	S	.	.	H	α-helix	trans	-60.8	-43	175.6	0	0	0	0	0	111.7	A244 L245 N246 M250 K251 L252	A244-A248 WeakPolarHBondContact O-CB 3.45Å; A244-A248 PolarHBondContact O-N 3.49Å; L245-A248 PolarHBondContact O-N 3.02Å; N246-A248 PolarHBondContact O-N 3.48Å; A248-M250 VanDerWaalsContact C-N 3.34Å; A248-M250 PolarHBondContact O-N 3.25Å; A248-K251 WeakPolarHBondContact O-CB 3.41Å; A248-K251 PolarHBondContact O-N 3.42Å; A248-L252 PolarHBondContact O-N 2.98Å
249	T	73.8	Confident	78	Confident	4 Å²	4	64 Å²	64	3%	0.025	33%	0.333	C	S	.	.	H	α-helix	trans	-65.3	-38.6	177.7	-54.4	0	0	0	0	111.3	V69 P72 L73 L245 N246 E247 K251 L252 V253	V69-T249 HydrophobicContact CB-CG2 4.42Å; P72-T249 HydrophobicContact CB-CG2 4.4Å; P72-T249 HydrophobicContact CG-CG2 4.09Å; L73-T249 HydrophobicContact CB-CG2 3.96Å; L73-T249 HydrophobicContact CD1-CG2 4.21Å; L245-T249 WeakPolarHBondContact O-CB 3.15Å; L245-T249 PolarHBondContact O-N 3.17Å; L245-T249 PolarHBondContact O-OG1 3.47Å; N246-T249 PolarHBondContact O-N 2.78Å; E247-T249 VanDerWaalsContact C-N 3.33Å; E247-T249 PolarHBondContact O-N 3.24Å; T249-K251 VanDerWaalsContact C-N 3.29Å; T249-K251 PolarHBondContact O-N 3.06Å; T249-L252 WeakPolarHBondContact O-CB 3.27Å; T249-L252 PolarHBondContact O-N 3.17Å; T249-L252 VanDerWaalsContact O-N 3.08Å; T249-V253 WeakPolarHBondContact O-CG2 3.36Å; T249-V253 PolarHBondContact O-N 3.25Å
250	M	65.7	Low	77.4	Confident	39 Å²	39	61.8 Å²	61.8	19%	0.192	32%	0.322	C	S	.	.	H	α-helix	trans	-62.6	-33.8	174.9	-73.5	-63.6	-69.7	0	0	113	L73 N246 E247 A248 V253 Q254 V413	L73-M250 HydrophobicContact CD1-CG 4.41Å; L73-M250 HydrophobicContact CD1-SD 3.97Å; N246-M250 WeakPolarHBondContact O-CG 3.3Å; N246-M250 PolarHBondContact O-N 2.77Å; E247-M250 PolarHBondContact O-N 3.34Å; A248-M250 VanDerWaalsContact C-N 3.34Å; A248-M250 PolarHBondContact O-N 3.25Å; M250-V253 WeakPolarHBondContact O-CB 3.48Å; M250-V253 PolarHBondContact O-N 3.4Å; M250-Q254 WeakPolarHBondContact O-CG 3.2Å; M250-Q254 PolarHBondContact O-N 2.77Å; M250-Q254 VanDerWaalsContact O-N 3.08Å; M250-V413 HydrophobicContact CE-CG1 3.87Å; M250-V413 HydrophobicContact SD-CG1 3.45Å; M250-V413 WeakPolarHBondContact SD-CG1 3.35Å
251	K	74.8	Confident	76.9	Confident	111 Å²	111	57.7 Å²	57.7	48%	0.483	30%	0.303	S	S	.	.	H	α-helix	trans	-66.1	-37.9	172.2	-69.1	175.1	-174	161.1	0	111.7	E247 A248 T249 Q254 I255	E247-K251 PolarHBondContact O-N 2.83Å; E247-K251 VanDerWaalsContact O-N 3.13Å; E247-K251 WeakPolarHBondContact OE1-CE 3.36Å; E247-K251 IonicContact OE1-NZ 2.94Å; E247-K251 PolarHBondContact OE1-NZ 3.46Å; A248-K251 WeakPolarHBondContact O-CB 3.41Å; A248-K251 PolarHBondContact O-N 3.42Å; T249-K251 VanDerWaalsContact C-N 3.29Å; T249-K251 PolarHBondContact O-N 3.06Å; K251-Q254 WeakPolarHBondContact O-CB 3.27Å; K251-Q254 PolarHBondContact O-N 3.41Å; K251-I255 PolarHBondContact O-N 3.11Å
252	L	75.5	Confident	76.5	Confident	94 Å²	94	57 Å²	57	49%	0.492	30%	0.3	S	S	.	.	H	α-helix	trans	-63.2	-42.4	172	-65	175.4	0	0	0	111.6	V69 A248 T249 Q254 I255 I256	V69-L252 HydrophobicContact CG1-CB 4.36Å; A248-L252 PolarHBondContact O-N 2.98Å; T249-L252 WeakPolarHBondContact O-CB 3.27Å; T249-L252 PolarHBondContact O-N 3.17Å; T249-L252 VanDerWaalsContact O-N 3.08Å; L252-Q254 VanDerWaalsContact C-N 3.28Å; L252-Q254 PolarHBondContact O-N 2.87Å; L252-I255 HydrophobicContact CD2-CD1 4.4Å; L252-I255 WeakPolarHBondContact O-CB 3.45Å; L252-I255 PolarHBondContact O-N 2.84Å; L252-I255 VanDerWaalsContact O-N 3.08Å; L252-I256 WeakPolarHBondContact O-CG1 3.4Å; L252-I256 PolarHBondContact O-N 2.92Å
253	V	65.3	Low	76.1	Confident	8 Å²	8	55.9 Å²	55.9	5%	0.048	30%	0.295	C	S	.	.	H	α-helix	trans	-56.5	-43.1	175.4	173.5	0	0	0	0	110.7	V69 T249 M250 I255 I256 M257 V413	V69-V253 HydrophobicContact CB-CG2 4.3Å; V69-V253 HydrophobicContact CG2-CG2 4.14Å; T249-V253 WeakPolarHBondContact O-CG2 3.36Å; T249-V253 PolarHBondContact O-N 3.25Å; M250-V253 WeakPolarHBondContact O-CB 3.48Å; M250-V253 PolarHBondContact O-N 3.4Å; V253-I255 VanDerWaalsContact C-N 3.31Å; V253-I255 PolarHBondContact O-N 3.19Å; V253-I256 WeakPolarHBondContact O-CB 3.35Å; V253-I256 PolarHBondContact O-N 3.39Å; V253-I256 VanDerWaalsContact O-N 3.1Å; V253-M257 HydrophobicContact CG1-CE 3.68Å; V253-M257 HydrophobicContact CG1-CG 4.34Å; V253-M257 VanDerWaalsContact O-CG 3.28Å; V253-M257 WeakPolarHBondContact O-CG 3.45Å; V253-M257 PolarHBondContact O-N 2.81Å; V253-V413 HydrophobicContact CG1-CB 4.28Å; V253-V413 HydrophobicContact CG1-CG1 4.3Å
254	Q	67.2	Low	75.7	Confident	125 Å²	125	52.4 Å²	52.4	58%	0.584	28%	0.277	S	S	*	.	H	α-helix	trans	-60.4	-37.6	176.9	-68.8	173	4.6	0	0	113.1	M250 K251 L252 I256 M257 C258	M250-Q254 WeakPolarHBondContact O-CG 3.2Å; M250-Q254 PolarHBondContact O-N 2.77Å; M250-Q254 VanDerWaalsContact O-N 3.08Å; K251-Q254 WeakPolarHBondContact O-CB 3.27Å; K251-Q254 PolarHBondContact O-N 3.41Å; L252-Q254 VanDerWaalsContact C-N 3.28Å; L252-Q254 PolarHBondContact O-N 2.87Å; Q254-I256 VanDerWaalsContact C-N 3.35Å; Q254-M257 WeakPolarHBondContact O-CB 3.4Å; Q254-M257 PolarHBondContact O-N 2.85Å; Q254-C258 PolarHBondContact O-N 3.32Å; Q254-C258 PolarHBondContact O-SG 3.11Å
255	I	80.6	Confident	75.6	Confident	110 Å²	110	50.7 Å²	50.7	56%	0.564	26%	0.259	S	S	*	.	H	α-helix	trans	-64.1	-43.3	174.6	-62.2	169.2	0	0	0	110.2	K251 L252 V253 M257 C258 Y259	K251-I255 PolarHBondContact O-N 3.11Å; L252-I255 HydrophobicContact CD2-CD1 4.4Å; L252-I255 WeakPolarHBondContact O-CB 3.45Å; L252-I255 PolarHBondContact O-N 2.84Å; L252-I255 VanDerWaalsContact O-N 3.08Å; V253-I255 VanDerWaalsContact C-N 3.31Å; V253-I255 PolarHBondContact O-N 3.19Å; I255-M257 VanDerWaalsContact C-N 3.3Å; I255-M257 PolarHBondContact O-N 3.02Å; I255-C258 WeakPolarHBondContact O-CB 3.33Å; I255-C258 PolarHBondContact O-N 3.4Å; I255-C258 VanDerWaalsContact O-N 3.17Å; I255-Y259 PolarHBondContact O-N 3.3Å
256	I	72.2	Confident	75.5	Confident	10 Å²	10	50 Å²	50	5%	0.051	25%	0.254	C	S	.	.	H	α-helix	trans	-63.3	-39.1	176.7	-59.4	168.3	0	0	0	110.7	L62 M65 L66 V69 L252 V253 Q254 C258 Y259 M260	L62-I256 HydrophobicContact CD1-CG2 4.12Å; M65-I256 HydrophobicContact CB-CD1 4.14Å; M65-I256 HydrophobicContact CB-CG1 4.15Å; M65-I256 HydrophobicContact CB-CG2 4.07Å; M65-I256 HydrophobicContact CE-CB 4.3Å; M65-I256 HydrophobicContact CE-CG1 3.76Å; M65-I256 HydrophobicContact CE-CG2 4.36Å; M65-I256 WeakPolarHBondContact O-CD1 3.43Å; L66-I256 HydrophobicContact CD2-CG2 3.89Å; L66-I256 HydrophobicContact CG-CG2 4.36Å; V69-I256 HydrophobicContact CB-CD1 4.32Å; V69-I256 HydrophobicContact CG1-CD1 3.39Å; V69-I256 HydrophobicContact CG2-CD1 3.94Å; L252-I256 WeakPolarHBondContact O-CG1 3.4Å; L252-I256 PolarHBondContact O-N 2.92Å; V253-I256 WeakPolarHBondContact O-CB 3.35Å; V253-I256 PolarHBondContact O-N 3.39Å; V253-I256 VanDerWaalsContact O-N 3.1Å; Q254-I256 VanDerWaalsContact C-N 3.35Å; I256-C258 VanDerWaalsContact C-N 3.26Å; I256-C258 PolarHBondContact O-N 2.87Å; I256-Y259 WeakPolarHBondContact O-CA 3.48Å; I256-Y259 WeakPolarHBondContact O-CB 3Å; I256-Y259 PolarHBondContact O-N 3.27Å; I256-M260 PolarHBondContact O-N 3.47Å
257	M	68.2	Low	75.3	Confident	17 Å²	17	49.4 Å²	49.4	8%	0.084	25%	0.251	C	S	.	.	H	α-helix	trans	-59	-36.7	175.3	-67	-64.9	145.1	0	0	111.9	L23 V253 Q254 I255 Y259 M260 P261 P414	L23-M257 WeakPolarHBondContact CD1-O 3.25Å; L23-M257 HydrophobicContact CD2-CB 4.16Å; V253-M257 HydrophobicContact CG1-CE 3.68Å; V253-M257 HydrophobicContact CG1-CG 4.34Å; V253-M257 VanDerWaalsContact O-CG 3.28Å; V253-M257 WeakPolarHBondContact O-CG 3.45Å; V253-M257 PolarHBondContact O-N 2.81Å; Q254-M257 WeakPolarHBondContact O-CB 3.4Å; Q254-M257 PolarHBondContact O-N 2.85Å; I255-M257 VanDerWaalsContact C-N 3.3Å; I255-M257 PolarHBondContact O-N 3.02Å; M257-Y259 VanDerWaalsContact C-N 3.27Å; M257-Y259 PolarHBondContact O-N 2.92Å; M257-M260 HydrophobicContact CE-CE 3.45Å; M257-M260 VanDerWaalsContact CE-CE 3.45Å; M257-M260 VanDerWaalsContact O-CB 3.25Å; M257-M260 WeakPolarHBondContact O-CB 3.17Å; M257-M260 PolarHBondContact O-N 3.37Å; M257-M260 VanDerWaalsContact O-N 3.16Å; M257-M260 HydrophobicContact SD-CE 3.17Å; M257-M260 WeakPolarHBondContact SD-CE 3.35Å; M257-M260 HydrophobicContact SD-SD 3.88Å; M257-P261 VanDerWaalsContact O-CD 3.3Å; M257-P261 WeakPolarHBondContact O-CD 3.33Å; M257-P414 HydrophobicContact CE-CB 3.65Å; M257-P414 VanDerWaalsContact CE-CD 3.44Å; M257-P414 HydrophobicContact CE-CG 3.46Å; M257-P414 VanDerWaalsContact CE-CG 3.46Å; M257-P414 HydrophobicContact SD-CB 3.92Å; M257-P414 HydrophobicContact SD-CG 3.6Å
258	C	77.2	Confident	75.3	Confident	80 Å²	80	44.6 Å²	44.6	54%	0.541	23%	0.228	S	C	.	.	H	α-helix	trans	-64	-31.7	174.9	-66.2	0	0	0	0	112.9	Q254 I255 I256	Q254-C258 PolarHBondContact O-N 3.32Å; Q254-C258 PolarHBondContact O-SG 3.11Å; I255-C258 WeakPolarHBondContact O-CB 3.33Å; I255-C258 PolarHBondContact O-N 3.4Å; I255-C258 VanDerWaalsContact O-N 3.17Å; I256-C258 VanDerWaalsContact C-N 3.26Å; I256-C258 PolarHBondContact O-N 2.87Å
259	Y	80.5	Confident	75.3	Confident	59 Å²	59	42.2 Å²	42.2	23%	0.231	21%	0.208	C	C	.	.	H	α-helix	trans	-79.1	-23.8	174.7	-177.9	-106.2	0	0	0	113	P58 I61 L62 M65 I255 I256 M257 F262 G263	P58-Y259 WeakPolarHBondContact CA-OH 3.47Å; P58-Y259 PolarHBondContact O-OH 3Å; I61-Y259 HydrophobicContact CB-CE1 4.44Å; I61-Y259 HydrophobicContact CG2-CE1 4.06Å; L62-Y259 HydrophobicContact CB-CD1 4.12Å; L62-Y259 HydrophobicContact CB-CE1 3.82Å; L62-Y259 HydrophobicContact CD1-CD1 4.07Å; M65-Y259 HydrophobicContact CE-CD1 4.49Å; M65-Y259 HydrophobicContact SD-CD1 3.89Å; M65-Y259 HydrophobicContact SD-CE1 4.22Å; M65-Y259 HydrophobicContact SD-CG 4.41Å; I255-Y259 PolarHBondContact O-N 3.3Å; I256-Y259 WeakPolarHBondContact O-CA 3.48Å; I256-Y259 WeakPolarHBondContact O-CB 3Å; I256-Y259 PolarHBondContact O-N 3.27Å; M257-Y259 VanDerWaalsContact C-N 3.27Å; M257-Y259 PolarHBondContact O-N 2.92Å; Y259-F262 HydrophobicContact CD2-CD1 4.3Å; Y259-F262 AromaticContact CE2-CD1 3.54Å; Y259-F262 HydrophobicContact CE2-CD1 3.54Å; Y259-F262 HydrophobicContact CE2-CE1 4.19Å; Y259-F262 AromaticContact CZ-CD1 3.91Å; Y259-F262 WeakPolarHBondContact O-CB 3.49Å; Y259-F262 PolarHBondContact O-N 3.44Å; Y259-G263 PolarHBondContact O-N 3.12Å; Y259-G263 VanDerWaalsContact O-N 3.08Å
260	M	71.9	Confident	75.5	Confident	11 Å²	11	42.4 Å²	42.4	5%	0.054	21%	0.211	C	C	.	.	H	α-helix	trans	-53.5	-45.6	-172.4	-179.8	-179.1	-68.2	0	0	114.9	L62 I256 M257 F262 G263 I264 N415	L62-M260 HydrophobicContact CD1-CB 4.3Å; L62-M260 HydrophobicContact CD2-CG 4.45Å; I256-M260 PolarHBondContact O-N 3.47Å; M257-M260 HydrophobicContact CE-CE 3.45Å; M257-M260 VanDerWaalsContact CE-CE 3.45Å; M257-M260 VanDerWaalsContact O-CB 3.25Å; M257-M260 WeakPolarHBondContact O-CB 3.17Å; M257-M260 PolarHBondContact O-N 3.37Å; M257-M260 VanDerWaalsContact O-N 3.16Å; M257-M260 HydrophobicContact SD-CE 3.17Å; M257-M260 WeakPolarHBondContact SD-CE 3.35Å; M257-M260 HydrophobicContact SD-SD 3.88Å; M260-F262 PolarHBondContact O-N 2.89Å; M260-G263 PolarHBondContact O-N 3.42Å; M260-I264 HydrophobicContact CG-CD1 3.37Å; M260-I264 HydrophobicContact CG-CG1 3.91Å; M260-I264 WeakPolarHBondContact O-CB 3.21Å; M260-I264 WeakPolarHBondContact O-CG1 3.45Å; M260-I264 PolarHBondContact O-N 3.25Å; M260-I264 HydrophobicContact SD-CD1 3.96Å; M260-N415 WeakPolarHBondContact CE-ND2 3.43Å
261	P	78.6	Confident	75.7	Confident	10 Å²	10	42.5 Å²	42.5	7%	0.065	21%	0.21	C	C	.	.	H	α-helix	trans	-57.6	-38.2	177.8	-25	34.1	0	0	0	112.6	L23 A26 S30 M257 L265	L23-P261 HydrophobicContact CD1-CG 4.21Å; A26-P261 HydrophobicContact CB-CB 3.95Å; A26-P261 HydrophobicContact CB-CG 3.82Å; S30-P261 WeakPolarHBondContact CB-O 3.29Å; S30-P261 VanDerWaalsContact OG-C 3.26Å; S30-P261 WeakPolarHBondContact OG-CB 3.19Å; S30-P261 PolarHBondContact OG-O 2.87Å; M257-P261 VanDerWaalsContact O-CD 3.3Å; M257-P261 WeakPolarHBondContact O-CD 3.33Å; P261-L265 PolarHBondContact O-N 3.44Å
262	F	85.3	Confident	75.8	Confident	106 Å²	106	37.6 Å²	37.6	47%	0.465	19%	0.189	S	C	.	.	H	α-helix	trans	-71.7	-45.3	178.7	-176.7	-104.1	0	0	0	111.6	P58 Y259 M260 L265 F266	P58-F262 HydrophobicContact CB-CD1 4.16Å; P58-F262 HydrophobicContact CB-CE1 3.7Å; P58-F262 HydrophobicContact CB-CZ 4.48Å; P58-F262 HydrophobicContact CG-CE1 4.14Å; Y259-F262 HydrophobicContact CD2-CD1 4.3Å; Y259-F262 AromaticContact CE2-CD1 3.54Å; Y259-F262 HydrophobicContact CE2-CD1 3.54Å; Y259-F262 HydrophobicContact CE2-CE1 4.19Å; Y259-F262 AromaticContact CZ-CD1 3.91Å; Y259-F262 WeakPolarHBondContact O-CB 3.49Å; Y259-F262 PolarHBondContact O-N 3.44Å; M260-F262 PolarHBondContact O-N 2.89Å; F262-L265 PolarHBondContact O-N 3.2Å; F262-F266 HydrophobicContact CD2-CE2 4.09Å; F262-F266 HydrophobicContact CE1-CD2 4.36Å; F262-F266 HydrophobicContact CE1-CE2 4.24Å; F262-F266 HydrophobicContact CE2-CD2 4.22Å; F262-F266 AromaticContact CE2-CE2 3.48Å; F262-F266 HydrophobicContact CE2-CE2 3.48Å; F262-F266 VanDerWaalsContact CE2-CE2 3.48Å; F262-F266 HydrophobicContact CE2-CZ 4.42Å; F262-F266 HydrophobicContact CZ-CD2 4.13Å; F262-F266 AromaticContact CZ-CE2 3.56Å; F262-F266 HydrophobicContact CZ-CE2 3.56Å; F262-F266 HydrophobicContact CZ-CZ 4.44Å; F262-F266 WeakPolarHBondContact O-CD2 3.43Å
263	G	78.1	Confident	76.1	Confident	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-63.4	-43	178.2	0	0	0	0	0	113.4	G59 Y259 M260 L265 F266 L267	G59-G263 WeakPolarHBondContact CA-O 3.38Å; Y259-G263 PolarHBondContact O-N 3.12Å; Y259-G263 VanDerWaalsContact O-N 3.08Å; M260-G263 PolarHBondContact O-N 3.42Å; G263-L265 VanDerWaalsContact C-N 3.34Å; G263-L265 PolarHBondContact O-N 3.3Å; G263-F266 PolarHBondContact O-N 2.71Å; G263-L267 VanDerWaalsContact O-CB 3.29Å; G263-L267 WeakPolarHBondContact O-CB 3.39Å; G263-L267 PolarHBondContact O-N 3.37Å
264	I	72.4	Confident	76.4	Confident	13 Å²	13	37 Å²	37	7%	0.067	18%	0.183	C	C	.	.	H	α-helix	trans	-62.2	-40.5	179.2	-71.8	177.2	0	0	0	111.4	T27 V31 L62 M260 F266 L267 I268 W443	T27-I264 HydrophobicContact CG2-CD1 3.88Å; V31-I264 HydrophobicContact CG2-CG2 3.79Å; L62-I264 HydrophobicContact CD2-CG1 3.89Å; M260-I264 HydrophobicContact CG-CD1 3.37Å; M260-I264 HydrophobicContact CG-CG1 3.91Å; M260-I264 WeakPolarHBondContact O-CB 3.21Å; M260-I264 WeakPolarHBondContact O-CG1 3.45Å; M260-I264 PolarHBondContact O-N 3.25Å; M260-I264 HydrophobicContact SD-CD1 3.96Å; I264-F266 PolarHBondContact O-N 3.39Å; I264-L267 PolarHBondContact O-N 3.25Å; I264-I268 HydrophobicContact CG2-CD1 3.51Å; I264-I268 HydrophobicContact CG2-CG1 4.12Å; I264-I268 WeakPolarHBondContact O-CB 3.43Å; I264-I268 WeakPolarHBondContact O-CG1 3.34Å; I264-I268 PolarHBondContact O-N 2.91Å; I264-W443 HydrophobicContact CD1-CB 4.3Å
265	L	82.4	Confident	76.5	Confident	23 Å²	23	31.8 Å²	31.8	12%	0.12	16%	0.16	C	C	.	.	H	α-helix	trans	-54.4	-52.3	178.8	-178.5	159.1	0	0	0	111.2	I33 G34 L37 P261 F262 G263 A269	I33-L265 HydrophobicContact CB-CD1 4.08Å; I33-L265 HydrophobicContact CG2-CD1 3.65Å; I33-L265 HydrophobicContact CG2-CG 4.24Å; G34-L265 WeakPolarHBondContact CA-O 3.31Å; L37-L265 HydrophobicContact CD2-CD2 3.94Å; P261-L265 PolarHBondContact O-N 3.44Å; F262-L265 PolarHBondContact O-N 3.2Å; G263-L265 VanDerWaalsContact C-N 3.34Å; G263-L265 PolarHBondContact O-N 3.3Å; L265-A269 VanDerWaalsContact O-CB 3.27Å; L265-A269 WeakPolarHBondContact O-CB 3.48Å; L265-A269 PolarHBondContact O-N 3.06Å
266	F	84.7	Confident	75.9	Confident	44 Å²	44	34.6 Å²	34.6	19%	0.193	17%	0.171	C	C	.	.	H	α-helix	trans	-74.3	-33.1	-179.2	-75.7	-80.5	0	0	0	112.9	F55 P58 F262 G263 I264 A269 A270	F55-F266 HydrophobicContact CE1-CD1 4.39Å; F55-F266 HydrophobicContact CE2-CD1 4.48Å; F55-F266 HydrophobicContact CE2-CE1 4.36Å; F55-F266 HydrophobicContact CZ-CD1 4.27Å; F55-F266 HydrophobicContact CZ-CE1 4.47Å; F55-F266 WeakPolarHBondContact O-CD1 3.49Å; P58-F266 HydrophobicContact CB-CB 3.98Å; P58-F266 HydrophobicContact CB-CD2 3.81Å; P58-F266 HydrophobicContact CB-CG 3.99Å; P58-F266 HydrophobicContact CG-CB 4.19Å; P58-F266 HydrophobicContact CG-CD1 4.32Å; P58-F266 HydrophobicContact CG-CD2 3.87Å; P58-F266 HydrophobicContact CG-CE2 4.36Å; P58-F266 HydrophobicContact CG-CG 3.85Å; F262-F266 HydrophobicContact CD2-CE2 4.09Å; F262-F266 HydrophobicContact CE1-CD2 4.36Å; F262-F266 HydrophobicContact CE1-CE2 4.24Å; F262-F266 HydrophobicContact CE2-CD2 4.22Å; F262-F266 AromaticContact CE2-CE2 3.48Å; F262-F266 HydrophobicContact CE2-CE2 3.48Å; F262-F266 VanDerWaalsContact CE2-CE2 3.48Å; F262-F266 HydrophobicContact CE2-CZ 4.42Å; F262-F266 HydrophobicContact CZ-CD2 4.13Å; F262-F266 AromaticContact CZ-CE2 3.56Å; F262-F266 HydrophobicContact CZ-CE2 3.56Å; F262-F266 HydrophobicContact CZ-CZ 4.44Å; F262-F266 WeakPolarHBondContact O-CD2 3.43Å; G263-F266 PolarHBondContact O-N 2.71Å; I264-F266 PolarHBondContact O-N 3.39Å; F266-A269 PolarHBondContact O-N 3.02Å; F266-A270 WeakPolarHBondContact O-CB 3.31Å; F266-A270 PolarHBondContact O-N 3.31Å
267	L	72.3	Confident	75.8	Confident	17 Å²	17	38.5 Å²	38.5	9%	0.089	19%	0.191	C	C	.	.	H	α-helix	trans	-62.2	-48.1	176.5	-164.9	155.7	0	0	0	110.8	M63 G263 I264 K271 V439	M63-L267 HydrophobicContact CG-CD1 3.79Å; M63-L267 HydrophobicContact SD-CD1 3.89Å; G263-L267 VanDerWaalsContact O-CB 3.29Å; G263-L267 WeakPolarHBondContact O-CB 3.39Å; G263-L267 PolarHBondContact O-N 3.37Å; I264-L267 PolarHBondContact O-N 3.25Å; L267-K271 HydrophobicContact CD2-CG 4.36Å; L267-K271 VanDerWaalsContact O-CG 3.29Å; L267-K271 WeakPolarHBondContact O-CG 3.47Å; L267-K271 PolarHBondContact O-N 3.48Å; L267-K271 VanDerWaalsContact O-N 3.11Å; L267-V439 HydrophobicContact CD1-CG1 3.66Å; L267-V439 HydrophobicContact CD2-CB 3.9Å; L267-V439 HydrophobicContact CD2-CG1 3.48Å; L267-V439 VanDerWaalsContact CD2-CG1 3.48Å; L267-V439 HydrophobicContact CG-CG1 4.23Å
268	I	72.9	Confident	76.1	Confident	5 Å²	5	44.8 Å²	44.8	3%	0.026	21%	0.214	C	C	.	.	H	α-helix	trans	-65.2	-48.5	177.3	-68.5	176.9	0	0	0	110.5	V31 I35 I264 A270 K271 I272 A440	V31-I268 HydrophobicContact CB-CD1 4.08Å; V31-I268 HydrophobicContact CG1-CD1 3.9Å; V31-I268 HydrophobicContact CG2-CD1 3.7Å; I35-I268 HydrophobicContact CG1-CG2 3.76Å; I264-I268 HydrophobicContact CG2-CD1 3.51Å; I264-I268 HydrophobicContact CG2-CG1 4.12Å; I264-I268 WeakPolarHBondContact O-CB 3.43Å; I264-I268 WeakPolarHBondContact O-CG1 3.34Å; I264-I268 PolarHBondContact O-N 2.91Å; I268-A270 VanDerWaalsContact C-N 3.34Å; I268-A270 PolarHBondContact O-N 3.38Å; I268-K271 PolarHBondContact O-N 3.18Å; I268-I272 HydrophobicContact CG2-CD1 3.72Å; I268-I272 HydrophobicContact CG2-CG1 4.41Å; I268-I272 VanDerWaalsContact O-CG1 3.31Å; I268-I272 WeakPolarHBondContact O-CG1 3.36Å; I268-I272 PolarHBondContact O-N 3.35Å; I268-A440 HydrophobicContact CG1-CB 4.12Å
269	A	82.6	Confident	76.2	Confident	0 Å²	0	43.9 Å²	43.9	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-59.2	-45.2	-179.2	0	0	0	0	0	111.7	G34 L37 F55 L265 F266 K271 I272 I273	G34-A269 WeakPolarHBondContact O-CA 3.07Å; G34-A269 VanDerWaalsContact O-CB 3.31Å; G34-A269 WeakPolarHBondContact O-CB 3.43Å; L37-A269 HydrophobicContact CB-CB 4.39Å; L37-A269 HydrophobicContact CD2-CB 4.3Å; L37-A269 HydrophobicContact CG-CB 4.4Å; F55-A269 HydrophobicContact CE1-CB 3.53Å; F55-A269 HydrophobicContact CZ-CB 3.87Å; L265-A269 VanDerWaalsContact O-CB 3.27Å; L265-A269 WeakPolarHBondContact O-CB 3.48Å; L265-A269 PolarHBondContact O-N 3.06Å; F266-A269 PolarHBondContact O-N 3.02Å; A269-K271 PolarHBondContact O-N 2.87Å; A269-I272 PolarHBondContact O-N 3.45Å; A269-I273 WeakPolarHBondContact O-CD1 3.42Å; A269-I273 VanDerWaalsContact O-CG1 3.26Å; A269-I273 WeakPolarHBondContact O-CG1 3.47Å; A269-I273 PolarHBondContact O-N 3.33Å
270	A	77.2	Confident	76.1	Confident	9 Å²	9	43.6 Å²	43.6	7%	0.074	20%	0.204	C	C	.	.	H	α-helix	trans	-61.8	-42.3	177.8	0	0	0	0	0	112.3	F55 F266 I268 I272 I273 E274	F55-A270 HydrophobicContact CD1-CB 4.04Å; F55-A270 HydrophobicContact CE1-CB 4.49Å; F266-A270 WeakPolarHBondContact O-CB 3.31Å; F266-A270 PolarHBondContact O-N 3.31Å; I268-A270 VanDerWaalsContact C-N 3.34Å; I268-A270 PolarHBondContact O-N 3.38Å; A270-I272 PolarHBondContact O-N 3.2Å; A270-I273 PolarHBondContact O-N 3.3Å; A270-E274 PolarHBondContact O-N 3.46Å
271	K	69.2	Low	76.3	Confident	40 Å²	40	46.3 Å²	46.3	17%	0.174	22%	0.216	C	C	.	.	H	α-helix	trans	-64.7	-39.8	177.9	-72.7	-71.7	144.3	-169.6	0	112.3	L267 I268 A269 I273 E274 V275 T436	L267-K271 HydrophobicContact CD2-CG 4.36Å; L267-K271 VanDerWaalsContact O-CG 3.29Å; L267-K271 WeakPolarHBondContact O-CG 3.47Å; L267-K271 PolarHBondContact O-N 3.48Å; L267-K271 VanDerWaalsContact O-N 3.11Å; I268-K271 PolarHBondContact O-N 3.18Å; A269-K271 PolarHBondContact O-N 2.87Å; K271-I273 VanDerWaalsContact C-N 3.26Å; K271-I273 PolarHBondContact O-N 2.97Å; K271-E274 WeakPolarHBondContact CE-OE2 3.39Å; K271-E274 IonicContact NZ-OE2 3.37Å; K271-E274 PolarHBondContact NZ-OE2 3.5Å; K271-E274 PolarHBondContact O-N 3.01Å; K271-E274 VanDerWaalsContact O-N 3.13Å; K271-V275 WeakPolarHBondContact O-CG2 3.25Å; K271-V275 PolarHBondContact O-N 3.45Å; K271-V275 VanDerWaalsContact O-N 3.14Å; K271-T436 PolarHBondContact NZ-OG1 2.96Å
272	I	77.4	Confident	76.6	Confident	8 Å²	8	50.1 Å²	50.1	4%	0.041	23%	0.229	C	C	.	.	H	α-helix	trans	-63.4	-33.9	176.9	-67.4	171.7	0	0	0	111.8	I35 G38 I39 I268 A269 A270 E274 V275 F281	I35-I272 VanDerWaalsContact CA-CD1 3.49Å; I35-I272 HydrophobicContact CB-CD1 4.08Å; I35-I272 HydrophobicContact CG1-CD1 4.01Å; I35-I272 HydrophobicContact CG2-CD1 4.16Å; G38-I272 VanDerWaalsContact C-CG2 3.5Å; I39-I272 HydrophobicContact CG1-CG2 4.12Å; I268-I272 HydrophobicContact CG2-CD1 3.72Å; I268-I272 HydrophobicContact CG2-CG1 4.41Å; I268-I272 VanDerWaalsContact O-CG1 3.31Å; I268-I272 WeakPolarHBondContact O-CG1 3.36Å; I268-I272 PolarHBondContact O-N 3.35Å; A269-I272 PolarHBondContact O-N 3.45Å; A270-I272 PolarHBondContact O-N 3.2Å; I272-E274 VanDerWaalsContact C-N 3.32Å; I272-V275 PolarHBondContact O-N 3.49Å; I272-F281 HydrophobicContact CB-CZ 4.36Å; I272-F281 HydrophobicContact CG1-CE1 4.1Å; I272-F281 HydrophobicContact CG1-CZ 3.86Å; I272-F281 HydrophobicContact CG2-CZ 4.08Å
273	I	81.4	Confident	76.6	Confident	9 Å²	9	45.7 Å²	45.7	5%	0.046	21%	0.209	C	C	.	.	H	α-helix	trans	-72.6	-25.2	176.9	-63.5	159	0	0	0	112.2	V41 L47 K52 F55 A269 A270 K271	V41-I273 HydrophobicContact CB-CD1 3.78Å; V41-I273 HydrophobicContact CB-CG1 4.09Å; V41-I273 HydrophobicContact CG1-CD1 3.43Å; V41-I273 VanDerWaalsContact CG1-CD1 3.43Å; V41-I273 HydrophobicContact CG1-CG1 3.91Å; L47-I273 HydrophobicContact CD1-CD1 4.46Å; L47-I273 HydrophobicContact CD1-CG2 4.42Å; K52-I273 HydrophobicContact CD-CG2 3.84Å; K52-I273 HydrophobicContact CG-CG2 3.92Å; K52-I273 PolarHBondContact NZ-O 3.38Å; F55-I273 HydrophobicContact CD1-CD1 3.68Å; F55-I273 HydrophobicContact CE1-CD1 3.46Å; F55-I273 VanDerWaalsContact CE1-CD1 3.46Å; F55-I273 HydrophobicContact CG-CD1 4.4Å; F55-I273 HydrophobicContact CZ-CD1 4.03Å; A269-I273 WeakPolarHBondContact O-CD1 3.42Å; A269-I273 VanDerWaalsContact O-CG1 3.26Å; A269-I273 WeakPolarHBondContact O-CG1 3.47Å; A269-I273 PolarHBondContact O-N 3.33Å; A270-I273 PolarHBondContact O-N 3.3Å; K271-I273 VanDerWaalsContact C-N 3.26Å; K271-I273 PolarHBondContact O-N 2.97Å
274	E	72.2	Confident	77	Confident	82 Å²	82	46.5 Å²	46.5	38%	0.383	21%	0.213	S	C	.	.	H	α-helix	trans	-80.6	-26.4	174.6	-73.1	176.4	177.8	0	0	112.7	A270 K271 I272 E276	A270-E274 PolarHBondContact O-N 3.46Å; K271-E274 WeakPolarHBondContact CE-OE2 3.39Å; K271-E274 IonicContact NZ-OE2 3.37Å; K271-E274 PolarHBondContact NZ-OE2 3.5Å; K271-E274 PolarHBondContact O-N 3.01Å; K271-E274 VanDerWaalsContact O-N 3.13Å; I272-E274 VanDerWaalsContact C-N 3.32Å; E274-E276 PolarHBondContact O-N 2.88Å
275	V	69.8	Low	77.7	Confident	14 Å²	14	47.3 Å²	47.3	9%	0.085	23%	0.225	C	C	.	.			trans	-72.7	113	-179	171.2	0	0	0	0	110.7	R42 K271 I272 D277 I280 F281	R42-V275 PolarHBondContact NE-O 3.2Å; R42-V275 PolarHBondContact NH1-O 3.46Å; R42-V275 PolarHBondContact NH2-O 3.24Å; K271-V275 WeakPolarHBondContact O-CG2 3.25Å; K271-V275 PolarHBondContact O-N 3.45Å; K271-V275 VanDerWaalsContact O-N 3.14Å; I272-V275 PolarHBondContact O-N 3.49Å; V275-D277 WeakPolarHBondContact CG1-O 3.48Å; V275-I280 HydrophobicContact CG1-CB 3.95Å; V275-I280 HydrophobicContact CG1-CD1 3.96Å; V275-I280 HydrophobicContact CG1-CG2 4.29Å; V275-I280 HydrophobicContact CG2-CG2 4.22Å; V275-F281 HydrophobicContact CB-CE2 4.27Å; V275-F281 HydrophobicContact CG1-CD2 4.16Å; V275-F281 HydrophobicContact CG1-CE2 3.69Å
276	E	67.1	Low	78.1	Confident	170 Å²	170	48.4 Å²	48.4	79%	0.794	23%	0.231	S	C	*	.			trans	-79.3	-33.8	178.2	-63.3	-175.6	171.5	0	0	112.2	R42 E274	R42-E276 PolarHBondContact NH2-O 2.9Å; E274-E276 PolarHBondContact O-N 2.88Å
277	D	71.4	Confident	78.5	Confident	91 Å²	91	46.3 Å²	46.3	49%	0.487	22%	0.222	S	C	.	.			trans	-113.2	134.3	-174.4	-95.6	-38.4	0	0	0	114.4	V275 E279 I280	V275-D277 WeakPolarHBondContact CG1-O 3.48Å; D277-E279 PolarHBondContact O-N 3.03Å; D277-I280 PolarHBondContact O-N 3.4Å
278	W	74.3	Confident	79.5	Confident	149 Å²	149	48.1 Å²	48.1	56%	0.564	23%	0.23	S	C	*	.	H	α-helix	trans	-65.7	-19.4	172.8	-71.7	106	0	0	0	113.1	I39 I280 F281 R282	I39-W278 HydrophobicContact CD1-CH2 4.38Å; I39-W278 HydrophobicContact CG1-CH2 4.26Å; W278-I280 PolarHBondContact O-N 2.88Å; W278-F281 AromaticContact CE3-CD2 3.61Å; W278-F281 HydrophobicContact CE3-CD2 3.61Å; W278-F281 AromaticContact CE3-CE2 3.88Å; W278-F281 HydrophobicContact CE3-CE2 3.88Å; W278-F281 HydrophobicContact CE3-CG 4.29Å; W278-F281 HydrophobicContact CZ3-CD2 4.04Å; W278-F281 AromaticContact CZ3-CE2 3.95Å; W278-F281 HydrophobicContact CZ3-CE2 3.95Å; W278-F281 HydrophobicContact CZ3-CZ 4.44Å; W278-F281 WeakPolarHBondContact O-CB 3.13Å; W278-F281 PolarHBondContact O-N 3.38Å; W278-F281 VanDerWaalsContact O-N 3.14Å; W278-R282 PolarHBondContact O-N 3.34Å
279	E	78.3	Confident	80.5	Confident	62 Å²	62	51.7 Å²	51.7	29%	0.29	25%	0.252	S	S	.	.	H	α-helix	trans	-61	-32.2	175.9	-157.1	-166.7	175	0	0	112	S124 D277 F281 R282 K283	S124-E279 WeakPolarHBondContact CA-OE1 3.4Å; S124-E279 WeakPolarHBondContact CB-OE1 3.37Å; S124-E279 PolarHBondContact OG-OE1 2.8Å; S124-E279 PolarHBondContact OG-OE2 3.4Å; D277-E279 PolarHBondContact O-N 3.03Å; E279-F281 VanDerWaalsContact C-N 3.26Å; E279-F281 PolarHBondContact O-N 3.18Å; E279-R282 WeakPolarHBondContact O-CB 2.86Å; E279-R282 PolarHBondContact O-N 3.5Å; E279-R282 IonicContact OE1-CZ 3.6Å; E279-R282 IonicContact OE1-NH2 2.83Å; E279-R282 PolarHBondContact OE1-NH2 3.45Å; E279-K283 WeakPolarHBondContact O-CG 3.45Å; E279-K283 PolarHBondContact O-N 2.95Å
280	I	78.1	Confident	81.2	Confident	52 Å²	52	51.7 Å²	51.7	27%	0.267	25%	0.252	S	S	.	.	H	α-helix	trans	-60.3	-38.2	177.6	-68.6	165.5	0	0	0	110.6	V275 D277 W278 R282 K283 M284	V275-I280 HydrophobicContact CG1-CB 3.95Å; V275-I280 HydrophobicContact CG1-CD1 3.96Å; V275-I280 HydrophobicContact CG1-CG2 4.29Å; V275-I280 HydrophobicContact CG2-CG2 4.22Å; D277-I280 PolarHBondContact O-N 3.4Å; W278-I280 PolarHBondContact O-N 2.88Å; I280-R282 VanDerWaalsContact C-N 3.34Å; I280-R282 PolarHBondContact O-N 3.38Å; I280-K283 PolarHBondContact O-N 3.22Å; I280-M284 HydrophobicContact CG2-CG 4.31Å; I280-M284 WeakPolarHBondContact O-CB 3.47Å; I280-M284 WeakPolarHBondContact O-CG 3.1Å; I280-M284 PolarHBondContact O-N 3.21Å
281	F	77.8	Confident	82.1	Confident	69 Å²	69	51.3 Å²	51.3	30%	0.303	25%	0.249	S	C	.	.	H	α-helix	trans	-65.5	-36.7	175.4	-71.3	-86.5	0	0	0	112.5	I272 V275 W278 E279 M284 G285	I272-F281 HydrophobicContact CB-CZ 4.36Å; I272-F281 HydrophobicContact CG1-CE1 4.1Å; I272-F281 HydrophobicContact CG1-CZ 3.86Å; I272-F281 HydrophobicContact CG2-CZ 4.08Å; V275-F281 HydrophobicContact CB-CE2 4.27Å; V275-F281 HydrophobicContact CG1-CD2 4.16Å; V275-F281 HydrophobicContact CG1-CE2 3.69Å; W278-F281 AromaticContact CE3-CD2 3.61Å; W278-F281 HydrophobicContact CE3-CD2 3.61Å; W278-F281 AromaticContact CE3-CE2 3.88Å; W278-F281 HydrophobicContact CE3-CE2 3.88Å; W278-F281 HydrophobicContact CE3-CG 4.29Å; W278-F281 HydrophobicContact CZ3-CD2 4.04Å; W278-F281 AromaticContact CZ3-CE2 3.95Å; W278-F281 HydrophobicContact CZ3-CE2 3.95Å; W278-F281 HydrophobicContact CZ3-CZ 4.44Å; W278-F281 WeakPolarHBondContact O-CB 3.13Å; W278-F281 PolarHBondContact O-N 3.38Å; W278-F281 VanDerWaalsContact O-N 3.14Å; E279-F281 VanDerWaalsContact C-N 3.26Å; E279-F281 PolarHBondContact O-N 3.18Å; F281-M284 PolarHBondContact O-N 3Å; F281-G285 PolarHBondContact O-N 2.91Å
282	R	83.8	Confident	83.4	Confident	89 Å²	89	51.5 Å²	51.5	34%	0.336	25%	0.252	S	S	.	.	H	α-helix	trans	-62.6	-46.1	173.7	-172.3	-172.8	69	80.1	3.5	110.7	W278 E279 I280 G285 L286	W278-R282 PolarHBondContact O-N 3.34Å; E279-R282 WeakPolarHBondContact O-CB 2.86Å; E279-R282 PolarHBondContact O-N 3.5Å; E279-R282 IonicContact OE1-CZ 3.6Å; E279-R282 IonicContact OE1-NH2 2.83Å; E279-R282 PolarHBondContact OE1-NH2 3.45Å; I280-R282 VanDerWaalsContact C-N 3.34Å; I280-R282 PolarHBondContact O-N 3.38Å; R282-G285 PolarHBondContact O-N 2.74Å; R282-L286 PolarHBondContact O-N 3.39Å
283	K	86.4	Confident	84.3	Confident	14 Å²	14	52.9 Å²	52.9	6%	0.061	26%	0.262	C	S	.	.	H	α-helix	trans	-61.8	-44	177	-65.3	-174.8	-179.9	-167.7	0	111.8	G122 S124 E279 I280 G285 L286 Y287 F382 L386	G122-K283 WeakPolarHBondContact O-CD 3.31Å; G122-K283 WeakPolarHBondContact O-CE 3.48Å; G122-K283 PolarHBondContact O-NZ 2.89Å; S124-K283 WeakPolarHBondContact OG-CE 3.21Å; S124-K283 PolarHBondContact OG-NZ 3.24Å; E279-K283 WeakPolarHBondContact O-CG 3.45Å; E279-K283 PolarHBondContact O-N 2.95Å; I280-K283 PolarHBondContact O-N 3.22Å; K283-G285 PolarHBondContact O-N 2.87Å; K283-L286 PolarHBondContact O-N 3.01Å; K283-Y287 WeakPolarHBondContact O-CB 3.35Å; K283-Y287 PolarHBondContact O-N 3.2Å; K283-F382 HydrophobicContact CB-CE2 4.26Å; K283-F382 HydrophobicContact CB-CZ 4.4Å; K283-L386 HydrophobicContact CB-CD2 4.3Å; K283-L386 HydrophobicContact CD-CD2 3.54Å
284	M	84.7	Confident	85.1	Confident	17 Å²	17	52.4 Å²	52.4	8%	0.084	26%	0.259	C	S	.	.	H	α-helix	trans	-59.5	-43.4	173.1	-69.6	-75.5	99.9	0	0	112.4	I280 F281 Y287 M288 F382 L386 L437	I280-M284 HydrophobicContact CG2-CG 4.31Å; I280-M284 WeakPolarHBondContact O-CB 3.47Å; I280-M284 WeakPolarHBondContact O-CG 3.1Å; I280-M284 PolarHBondContact O-N 3.21Å; F281-M284 PolarHBondContact O-N 3Å; M284-Y287 WeakPolarHBondContact O-CB 3.15Å; M284-Y287 PolarHBondContact O-N 2.86Å; M284-M288 WeakPolarHBondContact O-CB 3.11Å; M284-M288 PolarHBondContact O-N 3.41Å; M284-F382 HydrophobicContact CE-CD1 4.42Å; M284-F382 HydrophobicContact CE-CE1 3.14Å; M284-F382 HydrophobicContact CE-CE2 4.47Å; M284-F382 HydrophobicContact CE-CZ 3.16Å; M284-L386 HydrophobicContact CE-CD1 4.3Å; M284-L437 HydrophobicContact CE-CB 4.13Å; M284-L437 HydrophobicContact SD-CB 4.24Å
285	G	87.9	Confident	86.3	Confident	30 Å²	30	48.7 Å²	48.7	31%	0.309	24%	0.242	S	C	.	.	H	α-helix	trans	-62.8	-44.7	177.3	0	0	0	0	0	112.3	F281 R282 K283 M288 V289	F281-G285 PolarHBondContact O-N 2.91Å; R282-G285 PolarHBondContact O-N 2.74Å; K283-G285 PolarHBondContact O-N 2.87Å; G285-M288 WeakPolarHBondContact O-CB 3.14Å; G285-M288 PolarHBondContact O-N 3.44Å; G285-V289 WeakPolarHBondContact O-CG2 3.44Å; G285-V289 PolarHBondContact O-N 2.97Å
286	L	91	Very high	87.6	Confident	46 Å²	46	50.5 Å²	50.5	24%	0.241	26%	0.258	C	S	.	.	H	α-helix	trans	-67.6	-37	177.6	-168.6	59.2	0	0	0	111.9	I119 P121 R282 K283 V289 T290	I119-L286 HydrophobicContact CG2-CD1 3.8Å; I119-L286 HydrophobicContact CG2-CD2 4.11Å; I119-L286 HydrophobicContact CG2-CG 3.82Å; P121-L286 HydrophobicContact CB-CB 4.06Å; P121-L286 HydrophobicContact CB-CD2 4.26Å; P121-L286 HydrophobicContact CB-CG 3.92Å; R282-L286 PolarHBondContact O-N 3.39Å; K283-L286 PolarHBondContact O-N 3.01Å; L286-V289 PolarHBondContact O-N 3.4Å; L286-T290 WeakPolarHBondContact O-CB 3.49Å; L286-T290 PolarHBondContact O-N 3.29Å; L286-T290 PolarHBondContact O-OG1 2.88Å
287	Y	93.4	Very high	89.1	Confident	0 Å²	0	45 Å²	45	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-58.1	-48.9	169.7	162	-102.6	0	0	0	111.5	K283 M284 V289 T290 V291 Y375 V378 A379 F382 I438 V441 L445	K283-Y287 WeakPolarHBondContact O-CB 3.35Å; K283-Y287 PolarHBondContact O-N 3.2Å; M284-Y287 WeakPolarHBondContact O-CB 3.15Å; M284-Y287 PolarHBondContact O-N 2.86Å; Y287-V289 VanDerWaalsContact C-N 3.35Å; Y287-V289 PolarHBondContact O-N 3.41Å; Y287-T290 WeakPolarHBondContact O-CB 3.4Å; Y287-T290 PolarHBondContact O-N 3.44Å; Y287-T290 VanDerWaalsContact O-N 3.08Å; Y287-V291 HydrophobicContact CD2-CG2 4.16Å; Y287-V291 HydrophobicContact CE1-CG2 4.4Å; Y287-V291 HydrophobicContact CE2-CG2 3.61Å; Y287-V291 PolarHBondContact O-N 3.46Å; Y287-Y375 VanDerWaalsContact OH-CD2 3.25Å; Y287-Y375 WeakPolarHBondContact OH-CD2 3.26Å; Y287-Y375 WeakPolarHBondContact OH-CE2 3.32Å; Y287-V378 HydrophobicContact CD2-CG1 4.05Å; Y287-V378 HydrophobicContact CE2-CG1 3.9Å; Y287-A379 HydrophobicContact CE2-CB 4.1Å; Y287-F382 HydrophobicContact CD2-CB 3.84Å; Y287-F382 AromaticContact CD2-CD1 3.74Å; Y287-F382 HydrophobicContact CD2-CD1 3.74Å; Y287-F382 HydrophobicContact CD2-CD2 4.2Å; Y287-F382 HydrophobicContact CD2-CE1 4.4Å; Y287-F382 AromaticContact CD2-CG 3.62Å; Y287-F382 HydrophobicContact CD2-CG 3.62Å; Y287-F382 HydrophobicContact CE2-CB 4.31Å; Y287-F382 HydrophobicContact CE2-CD1 4.24Å; Y287-F382 HydrophobicContact CE2-CG 4.37Å; Y287-F382 HydrophobicContact CG-CD1 4.01Å; Y287-F382 HydrophobicContact CG-CD2 4.37Å; Y287-F382 HydrophobicContact CG-CE1 4.21Å; Y287-F382 HydrophobicContact CG-CG 4.09Å; Y287-F382 HydrophobicContact CG-CZ 4.44Å; Y287-I438 HydrophobicContact CE1-CG2 4.03Å; Y287-I438 WeakPolarHBondContact OH-CG2 3.46Å; Y287-V441 HydrophobicContact CD1-CG2 4.16Å; Y287-V441 HydrophobicContact CE1-CG2 3.84Å; Y287-L445 HydrophobicContact CE1-CD1 3.62Å
288	M	92.2	Very high	90.3	Very high	54 Å²	54	40.8 Å²	40.8	27%	0.266	21%	0.211	S	C	.	.	H	α-helix	trans	-59.7	-44.3	178.2	-174.3	-179.7	69	0	0	111.7	M284 G285 T290 V291 L292 L444 L445	M284-M288 WeakPolarHBondContact O-CB 3.11Å; M284-M288 PolarHBondContact O-N 3.41Å; G285-M288 WeakPolarHBondContact O-CB 3.14Å; G285-M288 PolarHBondContact O-N 3.44Å; M288-T290 VanDerWaalsContact C-N 3.31Å; M288-T290 PolarHBondContact O-N 2.89Å; M288-V291 PolarHBondContact O-N 3.39Å; M288-L292 HydrophobicContact CG-CD1 3.9Å; M288-L292 HydrophobicContact CG-CG 4.39Å; M288-L292 WeakPolarHBondContact O-CB 3.36Å; M288-L292 VanDerWaalsContact O-CG 3.25Å; M288-L292 WeakPolarHBondContact O-CG 3.21Å; M288-L292 PolarHBondContact O-N 3.21Å; M288-L444 HydrophobicContact SD-CD2 3.66Å; M288-L445 HydrophobicContact CG-CD2 3.83Å
289	V	94.6	Very high	91.3	Very high	81 Å²	81	34.2 Å²	34.2	49%	0.491	19%	0.189	S	C	.	.	H	α-helix	trans	-61.9	-39.3	174.8	171.5	0	0	0	0	111.5	G285 L286 Y287 S293	G285-V289 WeakPolarHBondContact O-CG2 3.44Å; G285-V289 PolarHBondContact O-N 2.97Å; L286-V289 PolarHBondContact O-N 3.4Å; Y287-V289 VanDerWaalsContact C-N 3.35Å; Y287-V289 PolarHBondContact O-N 3.41Å; V289-S293 VanDerWaalsContact O-CB 3.22Å; V289-S293 WeakPolarHBondContact O-CB 3.34Å; V289-S293 PolarHBondContact O-N 3.29Å; V289-S293 PolarHBondContact O-OG 3.01Å
290	T	96.3	Very high	92.2	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-62.7	-47.5	177.4	-57.4	0	0	0	0	111.4	L115 V116 I119 L286 Y287 M288 S293 G294 V378	L115-T290 HydrophobicContact CB-CG2 4.26Å; V116-T290 HydrophobicContact CB-CG2 4.17Å; I119-T290 HydrophobicContact CD1-CG2 4.07Å; I119-T290 WeakPolarHBondContact CG2-OG1 3.4Å; L286-T290 WeakPolarHBondContact O-CB 3.49Å; L286-T290 PolarHBondContact O-N 3.29Å; L286-T290 PolarHBondContact O-OG1 2.88Å; Y287-T290 WeakPolarHBondContact O-CB 3.4Å; Y287-T290 PolarHBondContact O-N 3.44Å; Y287-T290 VanDerWaalsContact O-N 3.08Å; M288-T290 VanDerWaalsContact C-N 3.31Å; M288-T290 PolarHBondContact O-N 2.89Å; T290-S293 PolarHBondContact O-OG 3.5Å; T290-G294 PolarHBondContact O-N 3.04Å; T290-V378 HydrophobicContact CG2-CG1 3.81Å
291	V	96.5	Very high	93	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-64.5	-49.6	176.9	177.2	0	0	0	0	110.9	Y287 M288 S293 G294 L295 Y375 V378 L445	Y287-V291 HydrophobicContact CD2-CG2 4.16Å; Y287-V291 HydrophobicContact CE1-CG2 4.4Å; Y287-V291 HydrophobicContact CE2-CG2 3.61Å; Y287-V291 PolarHBondContact O-N 3.46Å; M288-V291 PolarHBondContact O-N 3.39Å; V291-S293 VanDerWaalsContact C-N 3.35Å; V291-S293 PolarHBondContact O-N 2.84Å; V291-G294 PolarHBondContact O-N 2.88Å; V291-L295 HydrophobicContact CG1-CD1 3.95Å; V291-L295 HydrophobicContact CG1-CG 4.28Å; V291-L295 WeakPolarHBondContact O-CG 3.41Å; V291-L295 PolarHBondContact O-N 3.33Å; V291-Y375 HydrophobicContact CG1-CD2 4.28Å; V291-Y375 HydrophobicContact CG2-CD2 4.44Å; V291-V378 HydrophobicContact CG2-CB 4.1Å; V291-V378 HydrophobicContact CG2-CG1 3.59Å; V291-L445 HydrophobicContact CB-CD1 4.31Å; V291-L445 HydrophobicContact CB-CD2 4.02Å; V291-L445 HydrophobicContact CG1-CD1 4.27Å; V291-L445 HydrophobicContact CG1-CD2 3.9Å; V291-L445 HydrophobicContact CG2-CD1 4.32Å
292	L	96.3	Very high	93.9	Very high	45 Å²	45	34.8 Å²	34.8	24%	0.236	20%	0.201	C	C	.	.	H	α-helix	trans	-63.1	-39.7	-177.7	-70.1	175.9	0	0	0	112.5	M288 A296 L445 F448	M288-L292 HydrophobicContact CG-CD1 3.9Å; M288-L292 HydrophobicContact CG-CG 4.39Å; M288-L292 WeakPolarHBondContact O-CB 3.36Å; M288-L292 VanDerWaalsContact O-CG 3.25Å; M288-L292 WeakPolarHBondContact O-CG 3.21Å; M288-L292 PolarHBondContact O-N 3.21Å; L292-A296 VanDerWaalsContact O-CB 3.27Å; L292-A296 WeakPolarHBondContact O-CB 3.28Å; L292-A296 PolarHBondContact O-N 3.47Å; L292-L445 HydrophobicContact CD2-CD2 3.83Å; L292-L445 HydrophobicContact CG-CD2 3.81Å; L292-F448 HydrophobicContact CD2-CB 4.08Å; L292-F448 HydrophobicContact CD2-CD1 4.46Å; L292-F448 HydrophobicContact CD2-CD2 3.35Å; L292-F448 HydrophobicContact CD2-CE2 3.81Å; L292-F448 HydrophobicContact CD2-CG 3.72Å
293	S	97.3	Very high	94.5	Very high	36 Å²	36	30.6 Å²	30.6	25%	0.252	19%	0.185	S	C	.	.	H	α-helix	trans	-66.7	-40.9	174.7	58.4	0	0	0	0	111.8	V289 T290 V291 A296 I297	V289-S293 VanDerWaalsContact O-CB 3.22Å; V289-S293 WeakPolarHBondContact O-CB 3.34Å; V289-S293 PolarHBondContact O-N 3.29Å; V289-S293 PolarHBondContact O-OG 3.01Å; T290-S293 PolarHBondContact O-OG 3.5Å; V291-S293 VanDerWaalsContact C-N 3.35Å; V291-S293 PolarHBondContact O-N 2.84Å; S293-A296 PolarHBondContact O-N 3.46Å; S293-I297 WeakPolarHBondContact O-CB 3.44Å; S293-I297 VanDerWaalsContact O-CG1 3.24Å; S293-I297 WeakPolarHBondContact O-CG1 3.24Å; S293-I297 PolarHBondContact O-N 2.87Å
294	G	97.6	Very high	95	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-60.2	-47.8	173.6	0	0	0	0	0	112.9	T290 V291 A296 I297 H298	T290-G294 PolarHBondContact O-N 3.04Å; V291-G294 PolarHBondContact O-N 2.88Å; G294-A296 VanDerWaalsContact C-N 3.34Å; G294-A296 PolarHBondContact O-N 3.26Å; G294-I297 PolarHBondContact O-N 2.74Å; G294-H298 WeakPolarHBondContact O-CB 3.37Å; G294-H298 PolarHBondContact O-N 2.93Å
295	L	97.3	Very high	95.6	Very high	4 Å²	4	35.3 Å²	35.3	2%	0.021	21%	0.206	C	C	.	.	H	α-helix	trans	-61.1	-42.7	175.1	-67.2	175.9	0	0	0	111.7	V291 H298 A299 G371 L374 F448 R449 I452	V291-L295 HydrophobicContact CG1-CD1 3.95Å; V291-L295 HydrophobicContact CG1-CG 4.28Å; V291-L295 WeakPolarHBondContact O-CG 3.41Å; V291-L295 PolarHBondContact O-N 3.33Å; L295-H298 PolarHBondContact O-N 2.99Å; L295-A299 WeakPolarHBondContact O-CB 3.41Å; L295-A299 PolarHBondContact O-N 2.93Å; L295-G371 VanDerWaalsContact CD2-CA 3.45Å; L295-L374 HydrophobicContact CD2-CD2 4.28Å; L295-L374 HydrophobicContact CG-CD2 4.35Å; L295-F448 HydrophobicContact CD1-CB 3.77Å; L295-R449 HydrophobicContact CD1-CG 3.95Å; L295-R449 HydrophobicContact CD2-CG 4.5Å; L295-I452 HydrophobicContact CB-CG1 4.06Å; L295-I452 HydrophobicContact CD2-CB 4.42Å; L295-I452 HydrophobicContact CD2-CG1 4.1Å
296	A	97.3	Very high	96	Very high	51 Å²	51	35.3 Å²	35.3	42%	0.421	20%	0.198	S	C	.	.	H	α-helix	trans	-63.7	-45.9	178.2	0	0	0	0	0	111.9	L292 S293 G294 A299 T300	L292-A296 VanDerWaalsContact O-CB 3.27Å; L292-A296 WeakPolarHBondContact O-CB 3.28Å; L292-A296 PolarHBondContact O-N 3.47Å; S293-A296 PolarHBondContact O-N 3.46Å; G294-A296 VanDerWaalsContact C-N 3.34Å; G294-A296 PolarHBondContact O-N 3.26Å; A296-A299 PolarHBondContact O-N 3.25Å; A296-T300 WeakPolarHBondContact O-CB 3.43Å; A296-T300 WeakPolarHBondContact O-CG2 3.49Å; A296-T300 PolarHBondContact O-N 3.19Å; A296-T300 PolarHBondContact O-OG1 3.04Å
297	I	97.8	Very high	96.2	Very high	56 Å²	56	33.4 Å²	33.4	29%	0.287	19%	0.188	S	C	.	.	H	α-helix	trans	-62.2	-45.4	176.6	-70	164.3	0	0	0	110.1	L111 L115 S293 G294 A299 I301 C302	L111-I297 HydrophobicContact CD1-CG2 3.97Å; L111-I297 HydrophobicContact CD2-CB 4.15Å; L111-I297 HydrophobicContact CD2-CG2 3.78Å; L115-I297 HydrophobicContact CD1-CD1 4.19Å; L115-I297 HydrophobicContact CD2-CD1 4.29Å; S293-I297 WeakPolarHBondContact O-CB 3.44Å; S293-I297 VanDerWaalsContact O-CG1 3.24Å; S293-I297 WeakPolarHBondContact O-CG1 3.24Å; S293-I297 PolarHBondContact O-N 2.87Å; G294-I297 PolarHBondContact O-N 2.74Å; I297-A299 PolarHBondContact O-N 2.99Å; I297-I301 HydrophobicContact CG2-CB 4.49Å; I297-I301 HydrophobicContact CG2-CD1 4.3Å; I297-I301 WeakPolarHBondContact O-CA 3.26Å; I297-I301 VanDerWaalsContact O-CB 3.27Å; I297-I301 WeakPolarHBondContact O-CB 3.48Å; I297-I301 PolarHBondContact O-N 3.19Å; I297-C302 PolarHBondContact O-N 3.19Å
298	H	97.6	Very high	96.4	Very high	1 Å²	1	38.8 Å²	38.8	1%	0.005	21%	0.212	C	C	.	.	I	π-helix	trans	-61.9	-44.6	179.7	-166.1	70.1	0	0	0	112	L111 G294 L295 C302 L303 D370 L374	L111-H298 HydrophobicContact CD2-CB 3.87Å; G294-H298 WeakPolarHBondContact O-CB 3.37Å; G294-H298 PolarHBondContact O-N 2.93Å; L295-H298 PolarHBondContact O-N 2.99Å; H298-C302 WeakPolarHBondContact ND1-CB 3.31Å; H298-C302 WeakPolarHBondContact O-CB 3.25Å; H298-C302 PolarHBondContact O-N 3.46Å; H298-L303 PolarHBondContact O-N 2.87Å; H298-D370 IonicContact NE2-OD2 2.67Å; H298-L374 HydrophobicContact CB-CD1 4.45Å
299	A	96.1	Very high	96.7	Very high	12 Å²	12	40.6 Å²	40.6	10%	0.099	22%	0.222	C	C	.	.	I	π-helix	trans	-73	-33.5	-177.3	0	0	0	0	0	114.5	L295 A296 I297 P304 I452 L455	L295-A299 WeakPolarHBondContact O-CB 3.41Å; L295-A299 PolarHBondContact O-N 2.93Å; A296-A299 PolarHBondContact O-N 3.25Å; I297-A299 PolarHBondContact O-N 2.99Å; A299-P304 WeakPolarHBondContact O-CD 3.22Å; A299-P304 WeakPolarHBondContact O-CG 3.37Å; A299-I452 HydrophobicContact CB-CD1 3.36Å; A299-I452 HydrophobicContact CB-CG1 4.13Å; A299-L455 HydrophobicContact CB-CD2 4.01Å
300	T	95.7	Very high	96.7	Very high	69 Å²	69	39.7 Å²	39.7	42%	0.423	21%	0.213	S	C	.	.	I	π-helix	trans	-99.4	-25	-175.1	60.1	0	0	0	0	113.3	A296 P304 Y316	A296-T300 WeakPolarHBondContact O-CB 3.43Å; A296-T300 WeakPolarHBondContact O-CG2 3.49Å; A296-T300 PolarHBondContact O-N 3.19Å; A296-T300 PolarHBondContact O-OG1 3.04Å; T300-P304 WeakPolarHBondContact O-CG 3.36Å; T300-Y316 PolarHBondContact O-OH 3.08Å
301	I	96.4	Very high	96.7	Very high	101 Å²	101	40.3 Å²	40.3	52%	0.518	22%	0.217	S	C	.	.	I	π-helix	trans	-113.8	-61.5	-177.4	-52.8	-177.7	0	0	0	110.2	I297 F305	I297-I301 HydrophobicContact CG2-CB 4.49Å; I297-I301 HydrophobicContact CG2-CD1 4.3Å; I297-I301 WeakPolarHBondContact O-CA 3.26Å; I297-I301 VanDerWaalsContact O-CB 3.27Å; I297-I301 WeakPolarHBondContact O-CB 3.48Å; I297-I301 PolarHBondContact O-N 3.19Å; I301-F305 WeakPolarHBondContact O-CB 3.34Å; I301-F305 PolarHBondContact O-N 3.01Å
302	C	96.4	Very high	96.6	Very high	25 Å²	25	50.3 Å²	50.3	17%	0.169	26%	0.255	C	S	.	.	I	π-helix	trans	-63.6	-58	-170.7	-59.1	0	0	0	0	113.3	I107 I297 H298 F305 I306	I107-C302 HydrophobicContact CG2-CB 4.34Å; I297-C302 PolarHBondContact O-N 3.19Å; H298-C302 WeakPolarHBondContact ND1-CB 3.31Å; H298-C302 WeakPolarHBondContact O-CB 3.25Å; H298-C302 PolarHBondContact O-N 3.46Å; C302-F305 PolarHBondContact O-N 3.49Å; C302-I306 WeakPolarHBondContact O-CG1 3.46Å; C302-I306 PolarHBondContact O-N 3.48Å; C302-I306 VanDerWaalsContact O-N 3.07Å
303	L	96.3	Very high	96.4	Very high	0 Å²	0	55 Å²	55	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-63.4	-47	-178.5	-63.9	172.6	0	0	0	112.3	T104 H298 F305 I306 F307 I452 L455 Y459	T104-L303 HydrophobicContact CG2-CD2 3.76Å; H298-L303 PolarHBondContact O-N 2.87Å; L303-F305 VanDerWaalsContact C-N 3.29Å; L303-F305 PolarHBondContact O-N 2.69Å; L303-I306 PolarHBondContact O-N 3.08Å; L303-F307 PolarHBondContact O-N 3.1Å; L303-I452 HydrophobicContact CD1-CG2 4.37Å; L303-L455 HydrophobicContact CD1-CG 4.43Å; L303-Y459 HydrophobicContact CB-CD2 3.78Å; L303-Y459 HydrophobicContact CB-CE2 3.99Å; L303-Y459 HydrophobicContact CD1-CD2 4.41Å
304	P	96.7	Very high	96.3	Very high	4 Å²	4	57.6 Å²	57.6	3%	0.026	28%	0.284	C	S	.	.	H	α-helix	trans	-60.6	-36.6	176.1	-29.2	41.4	0	0	0	113.2	A299 T300 F307 F308 P315 Y459	A299-P304 WeakPolarHBondContact O-CD 3.22Å; A299-P304 WeakPolarHBondContact O-CG 3.37Å; T300-P304 WeakPolarHBondContact O-CG 3.36Å; P304-F307 PolarHBondContact O-N 3.38Å; P304-F308 VanDerWaalsContact O-CB 3.31Å; P304-F308 WeakPolarHBondContact O-CB 3.42Å; P304-F308 PolarHBondContact O-N 3.42Å; P304-P315 HydrophobicContact CB-CB 3.7Å; P304-P315 HydrophobicContact CB-CG 3.65Å; P304-Y459 HydrophobicContact CG-CE2 4.3Å
305	F	96.6	Very high	96.2	Very high	126 Å²	126	58 Å²	58	55%	0.553	29%	0.287	S	S	*	.	H	α-helix	trans	-65.7	-45.8	177.8	-179.8	-107.6	0	0	0	112	I301 C302 L303 F307 F308 I309	I301-F305 WeakPolarHBondContact O-CB 3.34Å; I301-F305 PolarHBondContact O-N 3.01Å; C302-F305 PolarHBondContact O-N 3.49Å; L303-F305 VanDerWaalsContact C-N 3.29Å; L303-F305 PolarHBondContact O-N 2.69Å; F305-F307 VanDerWaalsContact C-N 3.34Å; F305-F307 PolarHBondContact O-N 3.04Å; F305-F308 PolarHBondContact O-N 3.4Å; F305-I309 HydrophobicContact CD1-CD1 3.79Å; F305-I309 HydrophobicContact CD2-CD1 4.31Å; F305-I309 HydrophobicContact CE1-CD1 3.32Å; F305-I309 HydrophobicContact CE2-CD1 3.9Å; F305-I309 HydrophobicContact CE2-CG1 4.47Å; F305-I309 HydrophobicContact CG-CD1 4.27Å; F305-I309 HydrophobicContact CZ-CD1 3.4Å; F305-I309 VanDerWaalsContact CZ-CD1 3.4Å; F305-I309 HydrophobicContact CZ-CG1 4.42Å; F305-I309 WeakPolarHBondContact O-CG1 3.34Å; F305-I309 PolarHBondContact O-N 3.31Å
306	I	96.1	Very high	96.1	Very high	31 Å²	31	63.9 Å²	63.9	16%	0.159	31%	0.31	C	S	.	.	H	α-helix	trans	-59.9	-46.9	175.1	-65.7	167.1	0	0	0	110.2	Y100 T104 I107 C302 L303 F308 I309 I310 I463	Y100-I306 HydrophobicContact CE2-CG2 4.25Å; T104-I306 HydrophobicContact CG2-CD1 4.05Å; I107-I306 HydrophobicContact CD1-CD1 3.88Å; C302-I306 WeakPolarHBondContact O-CG1 3.46Å; C302-I306 PolarHBondContact O-N 3.48Å; C302-I306 VanDerWaalsContact O-N 3.07Å; L303-I306 PolarHBondContact O-N 3.08Å; I306-F308 VanDerWaalsContact C-N 3.35Å; I306-F308 PolarHBondContact O-N 2.93Å; I306-I309 PolarHBondContact O-N 2.95Å; I306-I310 HydrophobicContact CG2-CD1 3.89Å; I306-I310 WeakPolarHBondContact O-CG1 3.22Å; I306-I310 PolarHBondContact O-N 3.05Å; I306-I463 HydrophobicContact CG2-CD1 4.02Å
307	F	96.9	Very high	95.9	Very high	6 Å²	6	65.7 Å²	65.7	3%	0.026	32%	0.316	C	S	.	.	H	α-helix	trans	-60	-44.3	177	-175.7	-90.7	0	0	0	112.1	L303 P304 F305 I310 V311 K313 P315 F318 Y459 I463	L303-F307 PolarHBondContact O-N 3.1Å; P304-F307 PolarHBondContact O-N 3.38Å; F305-F307 VanDerWaalsContact C-N 3.34Å; F305-F307 PolarHBondContact O-N 3.04Å; F307-I310 PolarHBondContact O-N 3.21Å; F307-V311 HydrophobicContact CD1-CB 4.2Å; F307-V311 HydrophobicContact CD1-CG2 4.45Å; F307-V311 HydrophobicContact CD2-CB 4.38Å; F307-V311 HydrophobicContact CD2-CG2 3.77Å; F307-V311 HydrophobicContact CE1-CB 3.97Å; F307-V311 HydrophobicContact CE1-CG1 4.04Å; F307-V311 HydrophobicContact CE1-CG2 4.35Å; F307-V311 HydrophobicContact CE2-CB 4.18Å; F307-V311 HydrophobicContact CE2-CG1 4.32Å; F307-V311 HydrophobicContact CE2-CG2 3.67Å; F307-V311 HydrophobicContact CG-CB 4.43Å; F307-V311 HydrophobicContact CG-CG2 4.2Å; F307-V311 HydrophobicContact CZ-CB 3.97Å; F307-V311 HydrophobicContact CZ-CG1 3.81Å; F307-V311 HydrophobicContact CZ-CG2 3.99Å; F307-V311 WeakPolarHBondContact O-CA 3.48Å; F307-V311 VanDerWaalsContact O-CB 3.25Å; F307-V311 WeakPolarHBondContact O-CB 3.46Å; F307-V311 PolarHBondContact O-N 2.87Å; F307-K313 HydrophobicContact CE1-CB 4.28Å; F307-P315 HydrophobicContact CB-CB 4.36Å; F307-P315 HydrophobicContact CD1-CB 3.75Å; F307-P315 HydrophobicContact CE1-CB 4.48Å; F307-P315 HydrophobicContact CG-CB 4.38Å; F307-F318 HydrophobicContact CE1-CB 4.39Å; F307-F318 HydrophobicContact CE2-CD2 4.3Å; F307-F318 HydrophobicContact CE2-CE2 4.45Å; F307-F318 HydrophobicContact CE2-CG 4.36Å; F307-F318 HydrophobicContact CZ-CB 4.23Å; F307-F318 AromaticContact CZ-CD2 3.95Å; F307-F318 HydrophobicContact CZ-CD2 3.95Å; F307-F318 HydrophobicContact CZ-CE2 4.49Å; F307-F318 HydrophobicContact CZ-CG 4.02Å; F307-Y459 HydrophobicContact CB-CD1 3.71Å; F307-Y459 HydrophobicContact CB-CE1 3.84Å; F307-Y459 HydrophobicContact CB-CG 4.49Å; F307-Y459 HydrophobicContact CD1-CD1 4.38Å; F307-Y459 HydrophobicContact CD1-CE1 4.13Å; F307-Y459 AromaticContact CD2-CD1 3.31Å; F307-Y459 HydrophobicContact CD2-CD1 3.31Å; F307-Y459 AromaticContact CD2-CE1 3.9Å; F307-Y459 HydrophobicContact CD2-CE1 3.9Å; F307-Y459 HydrophobicContact CD2-CG 4.33Å; F307-Y459 AromaticContact CE2-CD1 3.92Å; F307-Y459 HydrophobicContact CE2-CD1 3.92Å; F307-Y459 HydrophobicContact CE2-CE1 4.43Å; F307-Y459 AromaticContact CG-CD1 3.55Å; F307-Y459 HydrophobicContact CG-CD1 3.55Å; F307-Y459 AromaticContact CG-CE1 3.69Å; F307-Y459 HydrophobicContact CG-CE1 3.69Å; F307-I463 HydrophobicContact CB-CD1 4.41Å; F307-I463 HydrophobicContact CD2-CD1 4.27Å; F307-I463 HydrophobicContact CD2-CG1 3.83Å
308	F	97.2	Very high	95.7	Very high	113 Å²	113	63.9 Å²	63.9	50%	0.496	31%	0.306	S	S	.	.	H	α-helix	trans	-63.8	-42.3	179.9	-179.3	-102.4	0	0	0	112.2	P304 F305 I306 I310 R312	P304-F308 VanDerWaalsContact O-CB 3.31Å; P304-F308 WeakPolarHBondContact O-CB 3.42Å; P304-F308 PolarHBondContact O-N 3.42Å; F305-F308 PolarHBondContact O-N 3.4Å; I306-F308 VanDerWaalsContact C-N 3.35Å; I306-F308 PolarHBondContact O-N 2.93Å; F308-I310 PolarHBondContact O-N 3.2Å; F308-R312 WeakPolarHBondContact O-CA 3.22Å; F308-R312 PolarHBondContact O-N 3.24Å
309	I	96.9	Very high	95.5	Very high	92 Å²	92	65.3 Å²	65.3	47%	0.472	32%	0.315	S	S	.	.	H	α-helix	trans	-62.6	-45.1	179.2	-72.9	171.9	0	0	0	111.5	F305 I306	F305-I309 HydrophobicContact CD1-CD1 3.79Å; F305-I309 HydrophobicContact CD2-CD1 4.31Å; F305-I309 HydrophobicContact CE1-CD1 3.32Å; F305-I309 HydrophobicContact CE2-CD1 3.9Å; F305-I309 HydrophobicContact CE2-CG1 4.47Å; F305-I309 HydrophobicContact CG-CD1 4.27Å; F305-I309 HydrophobicContact CZ-CD1 3.4Å; F305-I309 VanDerWaalsContact CZ-CD1 3.4Å; F305-I309 HydrophobicContact CZ-CG1 4.42Å; F305-I309 WeakPolarHBondContact O-CG1 3.34Å; F305-I309 PolarHBondContact O-N 3.31Å; I306-I309 PolarHBondContact O-N 2.95Å
310	I	96	Very high	95.2	Very high	62 Å²	62	71 Å²	71	32%	0.318	34%	0.343	S	S	.	.	H	α-helix	trans	-83.7	-48.7	-173	-58.5	170.8	0	0	0	111.5	I306 F307 F308 I463 L467	I306-I310 HydrophobicContact CG2-CD1 3.89Å; I306-I310 WeakPolarHBondContact O-CG1 3.22Å; I306-I310 PolarHBondContact O-N 3.05Å; F307-I310 PolarHBondContact O-N 3.21Å; F308-I310 PolarHBondContact O-N 3.2Å; I310-I463 HydrophobicContact CD1-CD1 4.45Å; I310-I463 HydrophobicContact CD1-CG2 3.95Å; I310-I463 HydrophobicContact CG2-CG2 4.01Å; I310-L467 HydrophobicContact CG2-CD1 4.42Å; I310-L467 HydrophobicContact CG2-CD2 3.91Å; I310-L467 HydrophobicContact CG2-CG 4.12Å
311	V	95.6	Very high	94.7	Very high	13 Å²	13	68.3 Å²	68.3	8%	0.079	33%	0.329	C	S	.	.	H	α-helix	trans	-85.1	-25.9	-174.2	-173.8	0	0	0	0	112	F307 K313 I463 K466	F307-V311 HydrophobicContact CD1-CB 4.2Å; F307-V311 HydrophobicContact CD1-CG2 4.45Å; F307-V311 HydrophobicContact CD2-CB 4.38Å; F307-V311 HydrophobicContact CD2-CG2 3.77Å; F307-V311 HydrophobicContact CE1-CB 3.97Å; F307-V311 HydrophobicContact CE1-CG1 4.04Å; F307-V311 HydrophobicContact CE1-CG2 4.35Å; F307-V311 HydrophobicContact CE2-CB 4.18Å; F307-V311 HydrophobicContact CE2-CG1 4.32Å; F307-V311 HydrophobicContact CE2-CG2 3.67Å; F307-V311 HydrophobicContact CG-CB 4.43Å; F307-V311 HydrophobicContact CG-CG2 4.2Å; F307-V311 HydrophobicContact CZ-CB 3.97Å; F307-V311 HydrophobicContact CZ-CG1 3.81Å; F307-V311 HydrophobicContact CZ-CG2 3.99Å; F307-V311 WeakPolarHBondContact O-CA 3.48Å; F307-V311 VanDerWaalsContact O-CB 3.25Å; F307-V311 WeakPolarHBondContact O-CB 3.46Å; F307-V311 PolarHBondContact O-N 2.87Å; V311-K313 HydrophobicContact CG1-CB 4.07Å; V311-K313 HydrophobicContact CG1-CD 4.07Å; V311-K313 HydrophobicContact CG1-CG 4.04Å; V311-K313 PolarHBondContact O-N 2.71Å; V311-I463 HydrophobicContact CG2-CB 4.48Å; V311-I463 HydrophobicContact CG2-CG1 3.86Å; V311-K466 HydrophobicContact CG1-CB 4.44Å; V311-K466 HydrophobicContact CG2-CB 4.1Å
312	R	94.7	Very high	94.4	Very high	209 Å²	209	63.5 Å²	63.5	79%	0.789	30%	0.304	S	S	*	.			trans	52.9	38.9	-175.2	-59.4	-153	-176.5	-177.9	3.3	113.6	F308	F308-R312 WeakPolarHBondContact O-CA 3.22Å; F308-R312 PolarHBondContact O-N 3.24Å
313	K	92.9	Very high	93.7	Very high	145 Å²	145	64.4 Å²	64.4	63%	0.63	31%	0.313	S	S	*	.	S	Bend	trans	-125	160.1	172.3	-71.2	-174.4	177	-177.1	0	109.7	F307 V311 P315	F307-K313 HydrophobicContact CE1-CB 4.28Å; V311-K313 HydrophobicContact CG1-CB 4.07Å; V311-K313 HydrophobicContact CG1-CD 4.07Å; V311-K313 HydrophobicContact CG1-CG 4.04Å; V311-K313 PolarHBondContact O-N 2.71Å; K313-P315 WeakPolarHBondContact O-CD 3.38Å
314	N	95.1	Very high	92.3	Very high	90 Å²	90	69.2 Å²	69.2	48%	0.481	34%	0.335	S	S	.	.			trans	-63.7	113.8	177.3	-174.4	-9.1	0	0	0	110.7	Y316 T317	N314-Y316 VanDerWaalsContact C-N 3.34Å; N314-Y316 PolarHBondContact O-N 3.44Å; N314-Y316 PolarHBondContact OD1-N 3.36Å; N314-T317 PolarHBondContact ND2-OG1 3.14Å
315	P	95.5	Very high	91.2	Very high	8 Å²	8	69 Å²	69	5%	0.052	33%	0.334	C	S	.	.	H	α-helix	trans	-69.4	-29.5	-178.3	28.2	-35.4	0	0	0	113	P304 F307 K313 T317 F318 T319 Y459	P304-P315 HydrophobicContact CB-CB 3.7Å; P304-P315 HydrophobicContact CB-CG 3.65Å; F307-P315 HydrophobicContact CB-CB 4.36Å; F307-P315 HydrophobicContact CD1-CB 3.75Å; F307-P315 HydrophobicContact CE1-CB 4.48Å; F307-P315 HydrophobicContact CG-CB 4.38Å; K313-P315 WeakPolarHBondContact O-CD 3.38Å; P315-T317 PolarHBondContact O-N 3.04Å; P315-F318 WeakPolarHBondContact O-CB 3.31Å; P315-F318 PolarHBondContact O-N 2.97Å; P315-F318 VanDerWaalsContact O-N 3.16Å; P315-T319 PolarHBondContact O-N 3.19Å; P315-T319 PolarHBondContact O-OG1 3.35Å; P315-T319 VanDerWaalsContact O-OG1 3.1Å; P315-Y459 HydrophobicContact CB-CE1 3.95Å; P315-Y459 WeakPolarHBondContact CB-OH 3.15Å; P315-Y459 PolarHBondContact O-OH 2.79Å
316	Y	94.8	Very high	90.6	Very high	127 Å²	127	63.9 Å²	63.9	50%	0.498	31%	0.312	S	S	.	.	H	α-helix	trans	-71.8	-33	-177.4	-61.5	-73.1	0	0	0	112.4	T300 N314 F318 T319 L320	T300-Y316 PolarHBondContact O-OH 3.08Å; N314-Y316 VanDerWaalsContact C-N 3.34Å; N314-Y316 PolarHBondContact O-N 3.44Å; N314-Y316 PolarHBondContact OD1-N 3.36Å; Y316-F318 VanDerWaalsContact C-N 3.27Å; Y316-F318 PolarHBondContact O-N 3.29Å; Y316-T319 PolarHBondContact O-N 3.49Å; Y316-L320 WeakPolarHBondContact O-CG 3.43Å; Y316-L320 PolarHBondContact O-N 3.32Å
317	T	92.8	Very high	89.5	Confident	89 Å²	89	66.5 Å²	66.5	55%	0.546	33%	0.329	S	S	.	.	H	α-helix	trans	-62.8	-38.8	170.8	-51.3	0	0	0	0	110.9	N314 P315 L320 G321	N314-T317 PolarHBondContact ND2-OG1 3.14Å; P315-T317 PolarHBondContact O-N 3.04Å; T317-L320 PolarHBondContact O-N 3.33Å; T317-G321 PolarHBondContact O-N 3.37Å
318	F	94	Very high	87.9	Confident	19 Å²	19	67.7 Å²	67.7	8%	0.083	34%	0.338	C	S	.	.	H	α-helix	trans	-66.4	-42.2	175.4	-177.7	-86.2	0	0	0	112	F307 P315 Y316 L320 G321 M322 N350 I352 A458 Y459	F307-F318 HydrophobicContact CE1-CB 4.39Å; F307-F318 HydrophobicContact CE2-CD2 4.3Å; F307-F318 HydrophobicContact CE2-CE2 4.45Å; F307-F318 HydrophobicContact CE2-CG 4.36Å; F307-F318 HydrophobicContact CZ-CB 4.23Å; F307-F318 AromaticContact CZ-CD2 3.95Å; F307-F318 HydrophobicContact CZ-CD2 3.95Å; F307-F318 HydrophobicContact CZ-CE2 4.49Å; F307-F318 HydrophobicContact CZ-CG 4.02Å; P315-F318 WeakPolarHBondContact O-CB 3.31Å; P315-F318 PolarHBondContact O-N 2.97Å; P315-F318 VanDerWaalsContact O-N 3.16Å; Y316-F318 VanDerWaalsContact C-N 3.27Å; Y316-F318 PolarHBondContact O-N 3.29Å; F318-L320 VanDerWaalsContact C-N 3.32Å; F318-L320 PolarHBondContact O-N 3.04Å; F318-G321 PolarHBondContact O-N 3.26Å; F318-G321 VanDerWaalsContact O-N 3.15Å; F318-M322 HydrophobicContact CE1-CG 4.19Å; F318-M322 PolarHBondContact O-N 3.42Å; F318-N350 HydrophobicContact CD2-CB 3.96Å; F318-N350 HydrophobicContact CE2-CB 3.71Å; F318-N350 WeakPolarHBondContact CE2-ND2 3.42Å; F318-N350 HydrophobicContact CZ-CB 4.45Å; F318-N350 PolarHBondContact O-ND2 3.2Å; F318-N350 PolarHBondContact O-OD1 3.24Å; F318-I352 HydrophobicContact CE2-CD1 3.76Å; F318-I352 HydrophobicContact CE2-CG1 4.31Å; F318-I352 HydrophobicContact CZ-CD1 3.76Å; F318-A458 HydrophobicContact CE1-CB 4.1Å; F318-A458 HydrophobicContact CZ-CB 4.5Å; F318-A458 WeakPolarHBondContact CZ-O 3.27Å; F318-Y459 AromaticContact CD1-CD1 3.71Å; F318-Y459 HydrophobicContact CD1-CD1 3.71Å; F318-Y459 AromaticContact CD1-CE1 3.65Å; F318-Y459 HydrophobicContact CD1-CE1 3.65Å; F318-Y459 AromaticContact CE1-CD1 3.9Å; F318-Y459 HydrophobicContact CE1-CD1 3.9Å; F318-Y459 HydrophobicContact CE1-CE1 4.3Å; F318-Y459 HydrophobicContact CE1-CG 4.45Å; F318-Y459 HydrophobicContact CG-CE1 4.39Å
319	T	92.9	Very high	86.9	Confident	31 Å²	31	62.3 Å²	62.3	19%	0.19	31%	0.314	C	S	.	.	H	α-helix	trans	-61.9	-40.8	175.9	-54.2	0	0	0	0	111.5	P315 Y316 G321 M322 A323 L326 L455 Y459	P315-T319 PolarHBondContact O-N 3.19Å; P315-T319 PolarHBondContact O-OG1 3.35Å; P315-T319 VanDerWaalsContact O-OG1 3.1Å; Y316-T319 PolarHBondContact O-N 3.49Å; T319-G321 VanDerWaalsContact C-N 3.26Å; T319-G321 PolarHBondContact O-N 3.46Å; T319-M322 CarbonylContact O-C 3.44Å; T319-M322 WeakPolarHBondContact O-CA 3.37Å; T319-M322 PolarHBondContact O-N 3.02Å; T319-A323 PolarHBondContact O-N 3.1Å; T319-A323 VanDerWaalsContact O-N 3.15Å; T319-L326 HydrophobicContact CG2-CD1 3.83Å; T319-L455 HydrophobicContact CG2-CD1 4.08Å; T319-Y459 PolarHBondContact OG1-OH 3.28Å
320	L	89.7	Confident	85.8	Confident	132 Å²	132	60.3 Å²	60.3	69%	0.691	30%	0.304	S	S	*	.	H	α-helix	trans	-60.4	-36.8	175.8	-76.6	168.1	0	0	0	111.9	Y316 T317 F318 M322 A323	Y316-L320 WeakPolarHBondContact O-CG 3.43Å; Y316-L320 PolarHBondContact O-N 3.32Å; T317-L320 PolarHBondContact O-N 3.33Å; F318-L320 VanDerWaalsContact C-N 3.32Å; F318-L320 PolarHBondContact O-N 3.04Å; L320-M322 PolarHBondContact O-N 3.03Å; L320-A323 VanDerWaalsContact O-CB 3.31Å; L320-A323 WeakPolarHBondContact O-CB 3.49Å; L320-A323 PolarHBondContact O-N 3.38Å
321	G	85.1	Confident	84.1	Confident	12 Å²	12	59.7 Å²	59.7	12%	0.124	30%	0.3	C	S	.	.	H	α-helix	trans	-62.1	-25.7	171.9	0	0	0	0	0	113.9	T317 F318 T319 N349	T317-G321 PolarHBondContact O-N 3.37Å; F318-G321 PolarHBondContact O-N 3.26Å; F318-G321 VanDerWaalsContact O-N 3.15Å; T319-G321 VanDerWaalsContact C-N 3.26Å; T319-G321 PolarHBondContact O-N 3.46Å; G321-N349 WeakPolarHBondContact O-CB 3.41Å; G321-N349 PolarHBondContact O-ND2 2.93Å
322	M	90.3	Very high	82.6	Confident	0 Å²	0	62.6 Å²	62.6	0%	0	32%	0.315	C	S	.	.	T	Hydrogen-bonded Turn	trans	-95.1	-1.3	177.4	-60.4	-56.4	-61.6	0	0	114.1	F318 T319 L320 Q324 A325 L326 T342 C345 A346 N350 A458	F318-M322 HydrophobicContact CE1-CG 4.19Å; F318-M322 PolarHBondContact O-N 3.42Å; T319-M322 CarbonylContact O-C 3.44Å; T319-M322 WeakPolarHBondContact O-CA 3.37Å; T319-M322 PolarHBondContact O-N 3.02Å; L320-M322 PolarHBondContact O-N 3.03Å; M322-Q324 VanDerWaalsContact C-N 3.25Å; M322-Q324 PolarHBondContact O-N 3.21Å; M322-Q324 VanDerWaalsContact O-N 3.09Å; M322-A325 HydrophobicContact CE-CB 4.01Å; M322-A325 WeakPolarHBondContact O-CA 3.36Å; M322-A325 WeakPolarHBondContact O-CB 3.44Å; M322-A325 PolarHBondContact O-N 3.4Å; M322-L326 HydrophobicContact CB-CD1 4.48Å; M322-L326 HydrophobicContact CB-CG 4.34Å; M322-L326 PolarHBondContact O-N 2.98Å; M322-T342 HydrophobicContact CE-CG2 3.61Å; M322-C345 HydrophobicContact CE-CB 3.87Å; M322-C345 HydrophobicContact SD-CB 3.69Å; M322-A346 HydrophobicContact SD-CB 4.27Å; M322-N350 WeakPolarHBondContact CG-ND2 3.27Å; M322-N350 PolarHBondContact SD-ND2 3.26Å; M322-N350 VanDerWaalsContact SD-ND2 3.44Å; M322-A458 HydrophobicContact CE-CB 3.7Å; M322-A458 HydrophobicContact CG-CB 3.94Å; M322-A458 HydrophobicContact SD-CB 4.14Å
323	A	81.8	Confident	81.6	Confident	43 Å²	43	53 Å²	53	36%	0.355	28%	0.28	S	S	.	.	H	α-helix	trans	-53.8	-39.1	-169.8	0	0	0	0	0	113.6	T319 L320 L326 V327	T319-A323 PolarHBondContact O-N 3.1Å; T319-A323 VanDerWaalsContact O-N 3.15Å; L320-A323 VanDerWaalsContact O-CB 3.31Å; L320-A323 WeakPolarHBondContact O-CB 3.49Å; L320-A323 PolarHBondContact O-N 3.38Å; A323-L326 PolarHBondContact O-N 2.92Å; A323-V327 WeakPolarHBondContact O-CG2 3.5Å; A323-V327 PolarHBondContact O-N 3.41Å
324	Q	65.7	Low	80.6	Confident	101 Å²	101	46.3 Å²	46.3	47%	0.472	25%	0.251	S	S	.	.	H	α-helix	trans	-63.6	-41.5	176.8	-178.5	179.7	-21.7	0	0	112.3	M322 T328 V341	M322-Q324 VanDerWaalsContact C-N 3.25Å; M322-Q324 PolarHBondContact O-N 3.21Å; M322-Q324 VanDerWaalsContact O-N 3.09Å; Q324-T328 WeakPolarHBondContact O-CB 2.91Å; Q324-T328 PolarHBondContact O-N 2.94Å; Q324-T328 PolarHBondContact O-OG1 3.01Å; Q324-V341 HydrophobicContact CG-CG1 4.02Å
325	A	75.1	Confident	79.8	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-66.9	-43.1	177	0	0	0	0	0	111.3	M322 V327 T328 A329 V341 C345	M322-A325 HydrophobicContact CE-CB 4.01Å; M322-A325 WeakPolarHBondContact O-CA 3.36Å; M322-A325 WeakPolarHBondContact O-CB 3.44Å; M322-A325 PolarHBondContact O-N 3.4Å; A325-V327 PolarHBondContact O-N 3.4Å; A325-T328 CarbonylContact O-C 3.55Å; A325-T328 WeakPolarHBondContact O-CB 3.29Å; A325-T328 PolarHBondContact O-N 2.87Å; A325-T328 VanDerWaalsContact O-N 3.14Å; A325-A329 WeakPolarHBondContact O-CB 3.48Å; A325-A329 PolarHBondContact O-N 3.41Å; A325-V341 HydrophobicContact CB-CG1 4.16Å; A325-C345 HydrophobicContact CB-CB 4.4Å
326	L	84.6	Confident	78.6	Confident	18 Å²	18	43.7 Å²	43.7	9%	0.094	24%	0.24	C	C	.	.	H	α-helix	trans	-62.5	-44.7	178.2	-61.4	178.3	0	0	0	112.4	T319 M322 A323 T328 A329 L330 M451 V454 L455	T319-L326 HydrophobicContact CG2-CD1 3.83Å; M322-L326 HydrophobicContact CB-CD1 4.48Å; M322-L326 HydrophobicContact CB-CG 4.34Å; M322-L326 PolarHBondContact O-N 2.98Å; A323-L326 PolarHBondContact O-N 2.92Å; L326-T328 VanDerWaalsContact C-N 3.31Å; L326-T328 PolarHBondContact O-N 3.13Å; L326-A329 PolarHBondContact O-N 3.31Å; L326-L330 PolarHBondContact O-N 3.35Å; L326-M451 HydrophobicContact CB-CG 3.94Å; L326-M451 HydrophobicContact CB-SD 4.37Å; L326-M451 HydrophobicContact CD2-CG 4.06Å; L326-M451 WeakPolarHBondContact CD2-O 3.25Å; L326-V454 HydrophobicContact CD2-CG1 4.42Å; L326-L455 HydrophobicContact CD1-CD1 4.18Å; L326-L455 HydrophobicContact CD2-CB 3.76Å; L326-L455 HydrophobicContact CD2-CD1 4.22Å; L326-L455 HydrophobicContact CD2-CG 4.48Å
327	V	72.7	Confident	76.9	Confident	86 Å²	86	39.9 Å²	39.9	52%	0.521	24%	0.235	S	C	.	.	H	α-helix	trans	-62.6	-42.4	173.7	172.5	0	0	0	0	110	A323 A325 A329 L330 M331	A323-V327 WeakPolarHBondContact O-CG2 3.5Å; A323-V327 PolarHBondContact O-N 3.41Å; A325-V327 PolarHBondContact O-N 3.4Å; V327-A329 VanDerWaalsContact C-N 3.31Å; V327-A329 PolarHBondContact O-N 2.97Å; V327-L330 PolarHBondContact O-N 3.06Å; V327-M331 HydrophobicContact CG1-CG 4.31Å; V327-M331 WeakPolarHBondContact O-CG 3.49Å; V327-M331 PolarHBondContact O-N 3.49Å; V327-M331 VanDerWaalsContact O-N 3.08Å
328	T	62.5	Low	75.7	Confident	32 Å²	32	35.7 Å²	35.7	20%	0.196	21%	0.209	C	C	.	.	H	α-helix	trans	-62.4	-39.9	177.1	-54.8	0	0	0	0	111.5	Q324 A325 L326 M331 I332 T338 V341	Q324-T328 WeakPolarHBondContact O-CB 2.91Å; Q324-T328 PolarHBondContact O-N 2.94Å; Q324-T328 PolarHBondContact O-OG1 3.01Å; A325-T328 CarbonylContact O-C 3.55Å; A325-T328 WeakPolarHBondContact O-CB 3.29Å; A325-T328 PolarHBondContact O-N 2.87Å; A325-T328 VanDerWaalsContact O-N 3.14Å; L326-T328 VanDerWaalsContact C-N 3.31Å; L326-T328 PolarHBondContact O-N 3.13Å; T328-M331 PolarHBondContact O-N 3.12Å; T328-I332 HydrophobicContact CG2-CD1 3.57Å; T328-I332 HydrophobicContact CG2-CG1 4.22Å; T328-I332 WeakPolarHBondContact O-CG1 3.4Å; T328-I332 PolarHBondContact O-N 3.11Å; T328-T338 HydrophobicContact CG2-CG2 4.11Å; T328-V341 HydrophobicContact CG2-CG2 4.28Å
329	A	75.3	Confident	74.5	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-64.3	-43	176.7	0	0	0	0	0	112.6	A325 L326 V327 M331 S333 T338 T450 V454	A325-A329 WeakPolarHBondContact O-CB 3.48Å; A325-A329 PolarHBondContact O-N 3.41Å; L326-A329 PolarHBondContact O-N 3.31Å; V327-A329 VanDerWaalsContact C-N 3.31Å; V327-A329 PolarHBondContact O-N 2.97Å; A329-M331 PolarHBondContact O-N 2.81Å; A329-S333 WeakPolarHBondContact O-CA 3.44Å; A329-S333 PolarHBondContact O-N 2.86Å; A329-T338 HydrophobicContact CB-CG2 3.87Å; A329-T450 HydrophobicContact CB-CG2 4.03Å; A329-V454 HydrophobicContact CB-CB 4.27Å; A329-V454 HydrophobicContact CB-CG2 3.9Å
330	L	75.5	Confident	73	Confident	49 Å²	49	39.1 Å²	39.1	26%	0.257	23%	0.232	S	C	.	.	H	α-helix	trans	-60.2	-35.6	173.2	-170.6	76	0	0	0	112.4	L326 V327 R447 F448 M451	L326-L330 PolarHBondContact O-N 3.35Å; V327-L330 PolarHBondContact O-N 3.06Å; L330-R447 HydrophobicContact CD1-CB 3.81Å; L330-R447 HydrophobicContact CG-CB 4.43Å; L330-R447 PolarHBondContact O-NH1 3.24Å; L330-F448 HydrophobicContact CD1-CD1 3.89Å; L330-F448 HydrophobicContact CD1-CE1 3.93Å; L330-F448 HydrophobicContact CD1-CG 4.24Å; L330-F448 HydrophobicContact CD1-CZ 4.33Å; L330-M451 HydrophobicContact CB-SD 4.47Å; L330-M451 HydrophobicContact CD1-SD 4.31Å
331	M	58.9	Low	71.7	Confident	50 Å²	50	34.6 Å²	34.6	25%	0.246	21%	0.21	C	C	.	.	H	α-helix	trans	-77.3	-46.2	-176.7	-64.2	-74.3	-64	0	0	112.1	N21 L24 V327 T328 A329 R447	N21-M331 HydrophobicContact CB-CE 3.59Å; N21-M331 WeakPolarHBondContact ND2-CE 3.21Å; N21-M331 VanDerWaalsContact OD1-CE 3.3Å; N21-M331 WeakPolarHBondContact OD1-CE 3.46Å; L24-M331 HydrophobicContact CD2-CE 3.16Å; L24-M331 HydrophobicContact CD2-SD 3.26Å; L24-M331 WeakPolarHBondContact CD2-SD 3.45Å; L24-M331 HydrophobicContact CG-CE 4.48Å; V327-M331 HydrophobicContact CG1-CG 4.31Å; V327-M331 WeakPolarHBondContact O-CG 3.49Å; V327-M331 PolarHBondContact O-N 3.49Å; V327-M331 VanDerWaalsContact O-N 3.08Å; T328-M331 PolarHBondContact O-N 3.12Å; A329-M331 PolarHBondContact O-N 2.81Å; M331-R447 PolarHBondContact O-NH1 3.27Å
332	I	64.9	Low	71.3	Confident	74 Å²	74	34.2 Å²	34.2	38%	0.379	21%	0.205	S	C	.	.	H	α-helix	trans	-86.9	-26	-174.6	-57.7	179.2	0	0	0	111.9	T328 S334 A337 T338	T328-I332 HydrophobicContact CG2-CD1 3.57Å; T328-I332 HydrophobicContact CG2-CG1 4.22Å; T328-I332 WeakPolarHBondContact O-CG1 3.4Å; T328-I332 PolarHBondContact O-N 3.11Å; I332-S334 PolarHBondContact O-N 3.32Å; I332-A337 HydrophobicContact CG2-CB 3.8Å; I332-T338 HydrophobicContact CB-CG2 4.33Å; I332-T338 HydrophobicContact CD1-CG2 4.37Å
333	S	72.8	Confident	70.4	Confident	8 Å²	8	36.3 Å²	36.3	6%	0.056	21%	0.214	C	C	.	.			trans	60.3	29.8	-177.2	-142.5	0	0	0	0	113.8	A329 P414 D446 R447 T450	A329-S333 WeakPolarHBondContact O-CA 3.44Å; A329-S333 PolarHBondContact O-N 2.86Å; S333-P414 VanDerWaalsContact O-CA 3.28Å; S333-P414 WeakPolarHBondContact O-CA 3.32Å; S333-P414 WeakPolarHBondContact O-CB 3.5Å; S333-P414 VanDerWaalsContact O-CG 3.27Å; S333-P414 WeakPolarHBondContact O-CG 3.36Å; S333-D446 VanDerWaalsContact OG-C 3.3Å; S333-D446 PolarHBondContact OG-O 3.06Å; S333-D446 PolarHBondContact OG-OD2 3.43Å; S333-R447 WeakPolarHBondContact OG-CA 3.34Å; S333-R447 PolarHBondContact OG-N 2.89Å; S333-T450 VanDerWaalsContact C-OG1 3.24Å; S333-T450 PolarHBondContact O-OG1 2.96Å
334	S	73	Confident	69.7	Low	4 Å²	4	40.7 Å²	40.7	3%	0.028	22%	0.221	C	C	.	.			trans	-141.8	118.6	177.5	170.3	0	0	0	0	111.5	I332 A337 T338 G412 T450	I332-S334 PolarHBondContact O-N 3.32Å; S334-A337 PolarHBondContact O-N 3.25Å; S334-A337 WeakPolarHBondContact OG-CB 3.4Å; S334-A337 PolarHBondContact OG-N 3.41Å; S334-A337 VanDerWaalsContact OG-N 3.15Å; S334-T338 WeakPolarHBondContact O-CG2 3.16Å; S334-T338 PolarHBondContact O-N 3.42Å; S334-T338 PolarHBondContact O-OG1 3.35Å; S334-G412 CarbonylContact C-O 3.14Å; S334-G412 WeakPolarHBondContact CA-O 3.43Å; S334-G412 WeakPolarHBondContact CB-O 3.22Å; S334-G412 PolarHBondContact OG-O 3.48Å; S334-T450 VanDerWaalsContact C-CG2 3.48Å; S334-T450 VanDerWaalsContact N-CG2 3.32Å
335	S	78.9	Confident	70.1	Confident	6 Å²	6	36 Å²	36	4%	0.042	20%	0.199	C	C	.	.	H	α-helix	trans	-62.4	-46	178.5	-57.7	0	0	0	0	110.7	A337 T338 L339 G412	S335-A337 PolarHBondContact O-N 2.98Å; S335-T338 PolarHBondContact O-N 2.89Å; S335-T338 PolarHBondContact O-OG1 2.96Å; S335-L339 PolarHBondContact O-N 3.26Å; S335-G412 PolarHBondContact N-O 3.45Å; S335-G412 VanDerWaalsContact N-O 3.16Å
336	S	69.3	Low	70.5	Confident	36 Å²	36	36 Å²	36	25%	0.252	20%	0.199	S	C	.	.	H	α-helix	trans	-64.5	-39.4	179.9	-51.2	0	0	0	0	112.7	T338 L339 G412	S336-T338 VanDerWaalsContact C-N 3.25Å; S336-T338 PolarHBondContact O-N 3.4Å; S336-L339 VanDerWaalsContact O-CB 3.23Å; S336-L339 WeakPolarHBondContact O-CB 3.43Å; S336-L339 PolarHBondContact O-N 2.76Å; S336-G412 PolarHBondContact N-O 3.49Å; S336-G412 WeakPolarHBondContact OG-CA 3.33Å; S336-G412 PolarHBondContact OG-O 2.84Å
337	A	60.3	Low	70.4	Confident	48 Å²	48	37 Å²	37	40%	0.397	20%	0.204	S	C	.	.	H	α-helix	trans	-69.8	-23.2	177.8	0	0	0	0	0	113.1	I332 S334 S335	I332-A337 HydrophobicContact CG2-CB 3.8Å; S334-A337 PolarHBondContact O-N 3.25Å; S334-A337 WeakPolarHBondContact OG-CB 3.4Å; S334-A337 PolarHBondContact OG-N 3.41Å; S334-A337 VanDerWaalsContact OG-N 3.15Å; S335-A337 PolarHBondContact O-N 2.98Å
338	T	65.9	Low	70.8	Confident	0 Å²	0	38.3 Å²	38.3	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-88.6	-10.8	179.3	66	0	0	0	0	113.7	T328 A329 I332 S334 S335 S336 P340 V341 T342 V454	T328-T338 HydrophobicContact CG2-CG2 4.11Å; A329-T338 HydrophobicContact CB-CG2 3.87Å; I332-T338 HydrophobicContact CB-CG2 4.33Å; I332-T338 HydrophobicContact CD1-CG2 4.37Å; S334-T338 WeakPolarHBondContact O-CG2 3.16Å; S334-T338 PolarHBondContact O-N 3.42Å; S334-T338 PolarHBondContact O-OG1 3.35Å; S335-T338 PolarHBondContact O-N 2.89Å; S335-T338 PolarHBondContact O-OG1 2.96Å; S336-T338 VanDerWaalsContact C-N 3.25Å; S336-T338 PolarHBondContact O-N 3.4Å; T338-P340 VanDerWaalsContact C-CD 3.44Å; T338-P340 VanDerWaalsContact C-N 3.35Å; T338-V341 PolarHBondContact O-N 2.92Å; T338-T342 PolarHBondContact O-N 2.96Å; T338-T342 PolarHBondContact O-OG1 3.35Å; T338-V454 WeakPolarHBondContact OG1-CG2 3.5Å
339	L	70.1	Confident	71.9	Confident	31 Å²	31	40.9 Å²	40.9	16%	0.162	22%	0.217	C	C	.	.	H	α-helix	trans	-50.8	-42.2	-173.7	-172.8	63.4	0	0	0	113.9	S335 S336 V341 T342 F343 L361 P362	S335-L339 PolarHBondContact O-N 3.26Å; S336-L339 VanDerWaalsContact O-CB 3.23Å; S336-L339 WeakPolarHBondContact O-CB 3.43Å; S336-L339 PolarHBondContact O-N 2.76Å; L339-V341 VanDerWaalsContact C-N 3.33Å; L339-V341 PolarHBondContact O-N 3.08Å; L339-T342 WeakPolarHBondContact O-CB 3.29Å; L339-T342 PolarHBondContact O-N 3.38Å; L339-F343 HydrophobicContact CD1-CD2 4.17Å; L339-F343 HydrophobicContact CD1-CE2 3.87Å; L339-F343 HydrophobicContact CD2-CE2 3.98Å; L339-F343 HydrophobicContact CG-CD2 3.84Å; L339-F343 HydrophobicContact CG-CE2 3.57Å; L339-F343 WeakPolarHBondContact O-CD2 3.16Å; L339-F343 PolarHBondContact O-N 2.93Å; L339-L361 HydrophobicContact CD1-CB 3.69Å; L339-P362 HydrophobicContact CD2-CB 4.17Å; L339-P362 HydrophobicContact CD2-CG 4.21Å
340	P	60.3	Low	72.6	Confident	92 Å²	92	42.5 Å²	42.5	60%	0.597	23%	0.225	S	C	*	.	H	α-helix	trans	-62.5	-35.6	177.2	-23.5	35.1	0	0	0	114	T338 R344	T338-P340 VanDerWaalsContact C-CD 3.44Å; T338-P340 VanDerWaalsContact C-N 3.35Å; P340-R344 PolarHBondContact O-N 3.22Å
341	V	62.4	Low	73.4	Confident	37 Å²	37	50.1 Å²	50.1	22%	0.224	25%	0.251	C	S	.	.	H	α-helix	trans	-74.3	-38	177	-176.9	0	0	0	0	110.1	Q324 A325 T328 T338 L339 R344 C345	Q324-V341 HydrophobicContact CG-CG1 4.02Å; A325-V341 HydrophobicContact CB-CG1 4.16Å; T328-V341 HydrophobicContact CG2-CG2 4.28Å; T338-V341 PolarHBondContact O-N 2.92Å; L339-V341 VanDerWaalsContact C-N 3.33Å; L339-V341 PolarHBondContact O-N 3.08Å; V341-R344 PolarHBondContact O-N 2.97Å; V341-C345 PolarHBondContact O-N 3.48Å; V341-C345 PolarHBondContact O-SG 3.12Å
342	T	77	Confident	74.9	Confident	4 Å²	4	48 Å²	48	3%	0.025	24%	0.241	C	C	.	.	H	α-helix	trans	-60.4	-46	174.1	-53.5	0	0	0	0	111.2	M322 T338 L339 R344 C345 A346 L361 V454	M322-T342 HydrophobicContact CE-CG2 3.61Å; T338-T342 PolarHBondContact O-N 2.96Å; T338-T342 PolarHBondContact O-OG1 3.35Å; L339-T342 WeakPolarHBondContact O-CB 3.29Å; L339-T342 PolarHBondContact O-N 3.38Å; T342-R344 PolarHBondContact O-N 2.95Å; T342-C345 PolarHBondContact O-N 2.91Å; T342-A346 VanDerWaalsContact O-CB 3.25Å; T342-A346 WeakPolarHBondContact O-CB 3.44Å; T342-A346 PolarHBondContact O-N 3.45Å; T342-L361 HydrophobicContact CG2-CD1 4.1Å; T342-L361 HydrophobicContact CG2-CD2 4.11Å; T342-V454 HydrophobicContact CG2-CG1 4.04Å; T342-V454 WeakPolarHBondContact OG1-CG1 3.3Å
343	F	72.1	Confident	75.8	Confident	44 Å²	44	46.4 Å²	46.4	19%	0.193	23%	0.233	C	C	.	.	H	α-helix	trans	-52.7	-55.1	173.5	-91.3	-64.1	0	0	0	112.1	L339 C345 A346 E347 T357 R358 L361 P362	L339-F343 HydrophobicContact CD1-CD2 4.17Å; L339-F343 HydrophobicContact CD1-CE2 3.87Å; L339-F343 HydrophobicContact CD2-CE2 3.98Å; L339-F343 HydrophobicContact CG-CD2 3.84Å; L339-F343 HydrophobicContact CG-CE2 3.57Å; L339-F343 WeakPolarHBondContact O-CD2 3.16Å; L339-F343 PolarHBondContact O-N 2.93Å; F343-C345 PolarHBondContact O-N 2.96Å; F343-A346 PolarHBondContact O-N 2.93Å; F343-E347 WeakPolarHBondContact O-CB 3.48Å; F343-E347 WeakPolarHBondContact O-CG 3.24Å; F343-E347 PolarHBondContact O-N 3.38Å; F343-T357 VanDerWaalsContact CE1-C 3.45Å; F343-T357 VanDerWaalsContact CE1-O 3.28Å; F343-T357 WeakPolarHBondContact CE1-O 3.26Å; F343-R358 HydrophobicContact CE1-CB 4.42Å; F343-R358 HydrophobicContact CE1-CG 4.01Å; F343-L361 HydrophobicContact CD1-CD1 3.93Å; F343-L361 HydrophobicContact CE1-CD1 4.15Å; F343-L361 HydrophobicContact CG-CD1 4.35Å; F343-L361 HydrophobicContact CZ-CB 4.43Å; F343-P362 HydrophobicContact CE2-CG 4.14Å; F343-P362 HydrophobicContact CZ-CG 3.64Å
344	R	66.2	Low	75.7	Confident	134 Å²	134	51.5 Å²	51.5	51%	0.506	25%	0.254	S	S	.	.	H	α-helix	trans	-59.7	-45.5	-178.4	-172.6	-177.8	156.8	-165.3	-11	111.9	P340 V341 T342 E348	P340-R344 PolarHBondContact O-N 3.22Å; V341-R344 PolarHBondContact O-N 2.97Å; T342-R344 PolarHBondContact O-N 2.95Å; R344-E348 HydrophobicContact CG-CG 4.1Å; R344-E348 WeakPolarHBondContact CG-OE2 3.45Å; R344-E348 IonicContact CZ-OE2 3.75Å; R344-E348 IonicContact NE-OE1 3.39Å; R344-E348 IonicContact NE-OE2 2.71Å; R344-E348 PolarHBondContact NE-OE2 2.96Å; R344-E348 IonicContact NH2-OE2 3.8Å; R344-E348 VanDerWaalsContact O-CB 3.23Å; R344-E348 WeakPolarHBondContact O-CB 3.23Å; R344-E348 WeakPolarHBondContact O-CG 3.42Å; R344-E348 PolarHBondContact O-N 3.45Å
345	C	75.2	Confident	75.7	Confident	2 Å²	2	55 Å²	55	1%	0.014	27%	0.267	C	S	.	.	I	π-helix	trans	-65.3	-40.7	179	-64.4	0	0	0	0	112	M322 A325 V341 T342 F343 N349 N350	M322-C345 HydrophobicContact CE-CB 3.87Å; M322-C345 HydrophobicContact SD-CB 3.69Å; A325-C345 HydrophobicContact CB-CB 4.4Å; V341-C345 PolarHBondContact O-N 3.48Å; V341-C345 PolarHBondContact O-SG 3.12Å; T342-C345 PolarHBondContact O-N 2.91Å; F343-C345 PolarHBondContact O-N 2.96Å; C345-N349 VanDerWaalsContact O-CB 3.25Å; C345-N349 WeakPolarHBondContact O-CB 3.42Å; C345-N349 PolarHBondContact O-N 2.9Å; C345-N349 VanDerWaalsContact O-N 3.12Å; C345-N350 PolarHBondContact O-N 2.94Å; C345-N350 VanDerWaalsContact O-N 3.16Å
346	A	83.3	Confident	75.8	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	27%	0.265	C	S	.	.	I	π-helix	trans	-65.2	-45.8	178.3	0	0	0	0	0	112.1	M322 T342 F343 N350 R351 I352 T357 L361	M322-A346 HydrophobicContact SD-CB 4.27Å; T342-A346 VanDerWaalsContact O-CB 3.25Å; T342-A346 WeakPolarHBondContact O-CB 3.44Å; T342-A346 PolarHBondContact O-N 3.45Å; F343-A346 PolarHBondContact O-N 2.93Å; A346-N350 CarbonylContact O-C 3.44Å; A346-N350 WeakPolarHBondContact O-CB 3.49Å; A346-R351 PolarHBondContact O-N 3.35Å; A346-R351 VanDerWaalsContact O-N 3.16Å; A346-I352 HydrophobicContact CB-CD1 4.04Å; A346-I352 WeakPolarHBondContact O-CG1 3.27Å; A346-I352 PolarHBondContact O-N 3.47Å; A346-T357 HydrophobicContact CB-CG2 3.93Å; A346-L361 HydrophobicContact CB-CD1 4.07Å
347	E	82.4	Confident	76.1	Confident	39 Å²	39	53 Å²	53	18%	0.182	25%	0.253	C	S	.	.	I	π-helix	trans	-79.2	-44.9	-176	-65.8	178.6	-173.5	0	0	112.8	F343 R351 K354 T357	F343-E347 WeakPolarHBondContact O-CB 3.48Å; F343-E347 WeakPolarHBondContact O-CG 3.24Å; F343-E347 PolarHBondContact O-N 3.38Å; E347-R351 VanDerWaalsContact O-CA 3.28Å; E347-R351 WeakPolarHBondContact O-CA 3.44Å; E347-R351 PolarHBondContact O-N 3.47Å; E347-K354 HydrophobicContact CG-CG 4.18Å; E347-K354 VanDerWaalsContact OE2-CE 3.3Å; E347-K354 WeakPolarHBondContact OE2-CE 3.3Å; E347-T357 HydrophobicContact CG-CG2 3.83Å; E347-T357 PolarHBondContact OE1-OG1 3.42Å
348	E	80.7	Confident	76.5	Confident	114 Å²	114	58.7 Å²	58.7	53%	0.533	26%	0.264	S	S	.	.	I	π-helix	trans	-84.7	-50.2	-174.9	-61.3	179.3	175.5	0	0	112	R344	R344-E348 HydrophobicContact CG-CG 4.1Å; R344-E348 WeakPolarHBondContact CG-OE2 3.45Å; R344-E348 IonicContact CZ-OE2 3.75Å; R344-E348 IonicContact NE-OE1 3.39Å; R344-E348 IonicContact NE-OE2 2.71Å; R344-E348 PolarHBondContact NE-OE2 2.96Å; R344-E348 IonicContact NH2-OE2 3.8Å; R344-E348 VanDerWaalsContact O-CB 3.23Å; R344-E348 WeakPolarHBondContact O-CB 3.23Å; R344-E348 WeakPolarHBondContact O-CG 3.42Å; R344-E348 PolarHBondContact O-N 3.45Å
349	N	85.1	Confident	76.6	Confident	86 Å²	86	59.9 Å²	59.9	46%	0.46	27%	0.269	S	S	.	.	I	π-helix	trans	-81.6	-45.3	-173.3	-56.3	-20.7	0	0	0	111.3	G321 C345	G321-N349 WeakPolarHBondContact O-CB 3.41Å; G321-N349 PolarHBondContact O-ND2 2.93Å; C345-N349 VanDerWaalsContact O-CB 3.25Å; C345-N349 WeakPolarHBondContact O-CB 3.42Å; C345-N349 PolarHBondContact O-N 2.9Å; C345-N349 VanDerWaalsContact O-N 3.12Å
350	N	90.3	Very high	77.1	Confident	34 Å²	34	58.4 Å²	58.4	18%	0.182	26%	0.261	C	S	.	.	S	Bend	trans	-95.5	-5.6	-176.6	-76.1	-27.6	0	0	0	114.1	F318 M322 C345 A346 I352	F318-N350 HydrophobicContact CD2-CB 3.96Å; F318-N350 HydrophobicContact CE2-CB 3.71Å; F318-N350 WeakPolarHBondContact CE2-ND2 3.42Å; F318-N350 HydrophobicContact CZ-CB 4.45Å; F318-N350 PolarHBondContact O-ND2 3.2Å; F318-N350 PolarHBondContact O-OD1 3.24Å; M322-N350 WeakPolarHBondContact CG-ND2 3.27Å; M322-N350 PolarHBondContact SD-ND2 3.26Å; M322-N350 VanDerWaalsContact SD-ND2 3.44Å; C345-N350 PolarHBondContact O-N 2.94Å; C345-N350 VanDerWaalsContact O-N 3.16Å; A346-N350 CarbonylContact O-C 3.44Å; A346-N350 WeakPolarHBondContact O-CB 3.49Å; N350-I352 VanDerWaalsContact C-N 3.28Å; N350-I352 HydrophobicContact CB-CG1 4.2Å; N350-I352 PolarHBondContact O-N 2.97Å
351	R	91.8	Very high	78	Confident	209 Å²	209	54.1 Å²	54.1	79%	0.789	23%	0.233	S	C	*	.			trans	55.1	41.1	176.5	-54.9	-175	-177.1	-173.1	0.4	113.3	A346 E347 Q465	A346-R351 PolarHBondContact O-N 3.35Å; A346-R351 VanDerWaalsContact O-N 3.16Å; E347-R351 VanDerWaalsContact O-CA 3.28Å; E347-R351 WeakPolarHBondContact O-CA 3.44Å; E347-R351 PolarHBondContact O-N 3.47Å; R351-Q465 PolarHBondContact O-NE2 3.33Å
352	I	90	Very high	78.3	Confident	6 Å²	6	54.5 Å²	54.5	3%	0.031	24%	0.236	C	C	.	.			trans	-76.3	139.7	171.9	-53.4	-178	0	0	0	109.1	F318 A346 N350 K354 I356 T357 A461 Q465	F318-I352 HydrophobicContact CE2-CD1 3.76Å; F318-I352 HydrophobicContact CE2-CG1 4.31Å; F318-I352 HydrophobicContact CZ-CD1 3.76Å; A346-I352 HydrophobicContact CB-CD1 4.04Å; A346-I352 WeakPolarHBondContact O-CG1 3.27Å; A346-I352 PolarHBondContact O-N 3.47Å; N350-I352 VanDerWaalsContact C-N 3.28Å; N350-I352 HydrophobicContact CB-CG1 4.2Å; N350-I352 PolarHBondContact O-N 2.97Å; I352-K354 PolarHBondContact O-N 3.01Å; I352-I356 HydrophobicContact CG2-CB 4.28Å; I352-I356 HydrophobicContact CG2-CG2 4.36Å; I352-T357 HydrophobicContact CB-CG2 3.68Å; I352-T357 HydrophobicContact CG2-CG2 3.47Å; I352-T357 VanDerWaalsContact CG2-CG2 3.47Å; I352-A461 HydrophobicContact CD1-CB 3.89Å; I352-A461 HydrophobicContact CG2-CB 4.36Å; I352-Q465 HydrophobicContact CG2-CB 4.35Å
353	D	84.1	Confident	78.2	Confident	41 Å²	41	54.5 Å²	54.5	22%	0.219	24%	0.237	C	C	.	.			trans	-61.6	132	177.6	-168.4	-62.6	0	0	0	110.9	R355 I356 T357 L472	D353-R355 PolarHBondContact O-N 3.49Å; D353-R355 VanDerWaalsContact OD1-CB 3.23Å; D353-R355 WeakPolarHBondContact OD1-CB 3.38Å; D353-R355 WeakPolarHBondContact OD1-CG 3.5Å; D353-R355 IonicContact OD1-CZ 3.85Å; D353-R355 PolarHBondContact OD1-N 3.23Å; D353-R355 IonicContact OD1-NE 2.82Å; D353-R355 PolarHBondContact OD1-NE 3.39Å; D353-R355 IonicContact OD1-NH2 3.17Å; D353-R355 IonicContact OD2-CZ 2.85Å; D353-R355 IonicContact OD2-NE 3.51Å; D353-R355 PolarHBondContact OD2-NE 3.06Å; D353-R355 IonicContact OD2-NH2 3.83Å; D353-R355 PolarHBondContact OD2-NH2 2.92Å; D353-I356 HydrophobicContact CB-CG1 4.22Å; D353-I356 WeakPolarHBondContact O-CB 3.49Å; D353-I356 PolarHBondContact O-N 3.02Å; D353-T357 PolarHBondContact O-N 3.47Å; D353-L472 HydrophobicContact CB-CD1 4.18Å; D353-L472 HydrophobicContact CB-CD2 4.42Å
354	K	71.1	Confident	78.6	Confident	115 Å²	115	52.4 Å²	52.4	50%	0.5	23%	0.227	S	C	.	.	H	α-helix	trans	-58.7	-30.3	-177.2	-61.4	-169.5	173.7	175.2	0	113.1	E347 I352 I356 T357 R358	E347-K354 HydrophobicContact CG-CG 4.18Å; E347-K354 VanDerWaalsContact OE2-CE 3.3Å; E347-K354 WeakPolarHBondContact OE2-CE 3.3Å; I352-K354 PolarHBondContact O-N 3.01Å; K354-I356 VanDerWaalsContact C-N 3.27Å; K354-I356 PolarHBondContact O-N 3.44Å; K354-T357 VanDerWaalsContact CA-OG1 3.29Å; K354-T357 WeakPolarHBondContact CA-OG1 3.35Å; K354-T357 PolarHBondContact O-OG1 2.94Å; K354-T357 VanDerWaalsContact O-OG1 3.12Å; K354-R358 WeakPolarHBondContact O-CB 3.43Å; K354-R358 WeakPolarHBondContact O-CD 3.47Å; K354-R358 WeakPolarHBondContact O-CG 3.29Å; K354-R358 PolarHBondContact O-N 3.44Å
355	R	74.1	Confident	79	Confident	78 Å²	78	46.2 Å²	46.2	29%	0.294	21%	0.205	S	C	.	.	H	α-helix	trans	-66.4	-33.3	177.5	-62.4	170.6	-74.2	-165.8	-1.5	111.3	D353 L472 D476	D353-R355 PolarHBondContact O-N 3.49Å; D353-R355 VanDerWaalsContact OD1-CB 3.23Å; D353-R355 WeakPolarHBondContact OD1-CB 3.38Å; D353-R355 WeakPolarHBondContact OD1-CG 3.5Å; D353-R355 IonicContact OD1-CZ 3.85Å; D353-R355 PolarHBondContact OD1-N 3.23Å; D353-R355 IonicContact OD1-NE 2.82Å; D353-R355 PolarHBondContact OD1-NE 3.39Å; D353-R355 IonicContact OD1-NH2 3.17Å; D353-R355 IonicContact OD2-CZ 2.85Å; D353-R355 IonicContact OD2-NE 3.51Å; D353-R355 PolarHBondContact OD2-NE 3.06Å; D353-R355 IonicContact OD2-NH2 3.83Å; D353-R355 PolarHBondContact OD2-NH2 2.92Å; R355-L472 HydrophobicContact CB-CD2 4.3Å; R355-D476 IonicContact CZ-OD1 3.46Å; R355-D476 IonicContact NH1-OD1 3.92Å; R355-D476 PolarHBondContact NH1-OD1 2.91Å; R355-D476 IonicContact NH2-OD1 3.87Å; R355-D476 PolarHBondContact NH2-OD1 3.37Å; R355-D476 IonicContact NH2-OD2 2.76Å
356	I	80.5	Confident	78.8	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-79.4	-49.1	176.1	-56.3	-61.7	0	0	0	110.4	I93 I352 D353 K354 R358 F359 V360 V464 Q465 L472	I93-I356 HydrophobicContact CD1-CD1 3.91Å; I93-I356 HydrophobicContact CG1-CD1 4.37Å; I93-I356 HydrophobicContact CG2-CD1 3.67Å; I352-I356 HydrophobicContact CG2-CB 4.28Å; I352-I356 HydrophobicContact CG2-CG2 4.36Å; D353-I356 HydrophobicContact CB-CG1 4.22Å; D353-I356 WeakPolarHBondContact O-CB 3.49Å; D353-I356 PolarHBondContact O-N 3.02Å; K354-I356 VanDerWaalsContact C-N 3.27Å; K354-I356 PolarHBondContact O-N 3.44Å; I356-R358 VanDerWaalsContact C-N 3.34Å; I356-R358 PolarHBondContact O-N 3.05Å; I356-F359 PolarHBondContact O-N 3.38Å; I356-V360 HydrophobicContact CG2-CB 4.44Å; I356-V360 HydrophobicContact CG2-CG2 3.71Å; I356-V360 WeakPolarHBondContact O-CB 3.21Å; I356-V360 WeakPolarHBondContact O-CG2 3.46Å; I356-V360 PolarHBondContact O-N 2.82Å; I356-V464 HydrophobicContact CD1-CG1 4.36Å; I356-V464 HydrophobicContact CG2-CB 4.29Å; I356-V464 HydrophobicContact CG2-CG1 4.14Å; I356-Q465 HydrophobicContact CG1-CB 4.41Å; I356-Q465 HydrophobicContact CG2-CB 4.47Å; I356-L472 HydrophobicContact CD1-CD1 4.28Å; I356-L472 HydrophobicContact CD1-CD2 4.07Å; I356-L472 HydrophobicContact CD1-CG 4.43Å; I356-L472 HydrophobicContact CG1-CD1 4.03Å; I356-L472 HydrophobicContact CG1-CD2 4.14Å
357	T	74.1	Confident	78.6	Confident	0 Å²	0	47.5 Å²	47.5	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-60.2	-43.8	-177.1	54	0	0	0	0	111.9	F343 A346 E347 I352 D353 K354 F359 L361 P362	F343-T357 VanDerWaalsContact CE1-C 3.45Å; F343-T357 VanDerWaalsContact CE1-O 3.28Å; F343-T357 WeakPolarHBondContact CE1-O 3.26Å; A346-T357 HydrophobicContact CB-CG2 3.93Å; E347-T357 HydrophobicContact CG-CG2 3.83Å; E347-T357 PolarHBondContact OE1-OG1 3.42Å; I352-T357 HydrophobicContact CB-CG2 3.68Å; I352-T357 HydrophobicContact CG2-CG2 3.47Å; I352-T357 VanDerWaalsContact CG2-CG2 3.47Å; D353-T357 PolarHBondContact O-N 3.47Å; K354-T357 VanDerWaalsContact CA-OG1 3.29Å; K354-T357 WeakPolarHBondContact CA-OG1 3.35Å; K354-T357 PolarHBondContact O-OG1 2.94Å; K354-T357 VanDerWaalsContact O-OG1 3.12Å; T357-F359 PolarHBondContact O-N 3.36Å; T357-L361 HydrophobicContact CG2-CD1 4.23Å; T357-L361 WeakPolarHBondContact O-CB 3.34Å; T357-L361 WeakPolarHBondContact O-CG 3.41Å; T357-L361 PolarHBondContact O-N 3.16Å; T357-L361 VanDerWaalsContact O-N 3.11Å; T357-P362 WeakPolarHBondContact O-CD 3.22Å
358	R	68.9	Low	79	Confident	167 Å²	167	45.7 Å²	45.7	63%	0.63	20%	0.203	S	C	*	.	H	α-helix	trans	-65.4	-18.1	-178.6	-71.8	174.8	179.5	-172.6	-4.4	113.8	F343 K354 I356 P362	F343-R358 HydrophobicContact CE1-CB 4.42Å; F343-R358 HydrophobicContact CE1-CG 4.01Å; K354-R358 WeakPolarHBondContact O-CB 3.43Å; K354-R358 WeakPolarHBondContact O-CD 3.47Å; K354-R358 WeakPolarHBondContact O-CG 3.29Å; K354-R358 PolarHBondContact O-N 3.44Å; I356-R358 VanDerWaalsContact C-N 3.34Å; I356-R358 PolarHBondContact O-N 3.05Å; R358-P362 WeakPolarHBondContact O-CG 3.47Å
359	F	68.2	Low	79.5	Confident	25 Å²	25	40.4 Å²	40.4	11%	0.11	18%	0.179	C	C	.	.	H	α-helix	trans	-97.9	-55.6	176.5	-174.7	-88.6	0	0	0	111.6	A84 L85 S90 I93 I356 T357 V363	A84-F359 WeakPolarHBondContact O-CE2 3.48Å; L85-F359 HydrophobicContact CB-CE2 4.47Å; L85-F359 HydrophobicContact CB-CZ 4.09Å; L85-F359 HydrophobicContact CD2-CE1 3.64Å; L85-F359 HydrophobicContact CD2-CE2 3.88Å; L85-F359 HydrophobicContact CD2-CZ 3.15Å; L85-F359 HydrophobicContact CG-CZ 4.18Å; S90-F359 WeakPolarHBondContact OG-CD2 3.28Å; S90-F359 WeakPolarHBondContact OG-CE2 3.38Å; S90-F359 WeakPolarHBondContact OG-CZ 3.31Å; I93-F359 HydrophobicContact CG2-CD1 4.43Å; I356-F359 PolarHBondContact O-N 3.38Å; T357-F359 PolarHBondContact O-N 3.36Å; F359-V363 WeakPolarHBondContact O-CG2 3.29Å
360	V	81.9	Confident	79.9	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-70.6	-45.2	-168.6	178.3	0	0	0	0	111.1	A97 Y101 I356 G364 A461 V464	A97-V360 HydrophobicContact CB-CG1 4.48Å; A97-V360 HydrophobicContact CB-CG2 4.25Å; Y101-V360 WeakPolarHBondContact OH-CG1 3.25Å; Y101-V360 PolarHBondContact OH-O 3.11Å; I356-V360 HydrophobicContact CG2-CB 4.44Å; I356-V360 HydrophobicContact CG2-CG2 3.71Å; I356-V360 WeakPolarHBondContact O-CB 3.21Å; I356-V360 WeakPolarHBondContact O-CG2 3.46Å; I356-V360 PolarHBondContact O-N 2.82Å; V360-G364 PolarHBondContact O-N 3.08Å; V360-A461 HydrophobicContact CB-CB 4.33Å; V360-A461 HydrophobicContact CG1-CB 4.07Å; V360-V464 HydrophobicContact CG2-CB 4.26Å; V360-V464 HydrophobicContact CG2-CG1 4.06Å; V360-V464 HydrophobicContact CG2-CG2 4.43Å
361	L	78.3	Confident	80.1	Confident	1 Å²	1	34.7 Å²	34.7	1%	0.005	15%	0.148	C	C	.	.	H	α-helix	trans	-69.4	-44.2	-172.6	-58.5	174.8	0	0	0	113.8	L339 T342 F343 A346 T357 V363 G364 A365 D457 A461	L339-L361 HydrophobicContact CD1-CB 3.69Å; T342-L361 HydrophobicContact CG2-CD1 4.1Å; T342-L361 HydrophobicContact CG2-CD2 4.11Å; F343-L361 HydrophobicContact CD1-CD1 3.93Å; F343-L361 HydrophobicContact CE1-CD1 4.15Å; F343-L361 HydrophobicContact CG-CD1 4.35Å; F343-L361 HydrophobicContact CZ-CB 4.43Å; A346-L361 HydrophobicContact CB-CD1 4.07Å; T357-L361 HydrophobicContact CG2-CD1 4.23Å; T357-L361 WeakPolarHBondContact O-CB 3.34Å; T357-L361 WeakPolarHBondContact O-CG 3.41Å; T357-L361 PolarHBondContact O-N 3.16Å; T357-L361 VanDerWaalsContact O-N 3.11Å; L361-V363 VanDerWaalsContact C-N 3.35Å; L361-V363 PolarHBondContact O-N 3.04Å; L361-G364 PolarHBondContact O-N 3.5Å; L361-A365 WeakPolarHBondContact O-CB 3.48Å; L361-A365 PolarHBondContact O-N 3.17Å; L361-D457 HydrophobicContact CD2-CB 4.06Å; L361-A461 HydrophobicContact CD2-CB 4.02Å; L361-A461 HydrophobicContact CG-CB 4.46Å
362	P	68.6	Low	80.2	Confident	45 Å²	45	25 Å²	25	29%	0.292	11%	0.112	S	C	.	.	H	α-helix	trans	-63.8	-39.8	177	-24.2	35.7	0	0	0	113.1	L339 F343 T357 R358	L339-P362 HydrophobicContact CD2-CB 4.17Å; L339-P362 HydrophobicContact CD2-CG 4.21Å; F343-P362 HydrophobicContact CE2-CG 4.14Å; F343-P362 HydrophobicContact CZ-CG 3.64Å; T357-P362 WeakPolarHBondContact O-CD 3.22Å; R358-P362 WeakPolarHBondContact O-CG 3.47Å
363	V	75.1	Confident	80.4	Confident	5 Å²	5	24.7 Å²	24.7	3%	0.03	11%	0.111	C	C	.	.	H	α-helix	trans	-68	-41.3	176.7	175.4	0	0	0	0	110.7	L85 Y101 F359 L361 T366 I367	L85-V363 HydrophobicContact CD2-CB 4.36Å; L85-V363 HydrophobicContact CD2-CG1 3.86Å; L85-V363 HydrophobicContact CD2-CG2 3.61Å; Y101-V363 HydrophobicContact CE2-CG1 4.15Å; F359-V363 WeakPolarHBondContact O-CG2 3.29Å; L361-V363 VanDerWaalsContact C-N 3.35Å; L361-V363 PolarHBondContact O-N 3.04Å; V363-T366 PolarHBondContact O-N 3.27Å; V363-T366 PolarHBondContact O-OG1 2.95Å; V363-T366 VanDerWaalsContact O-OG1 3.08Å; V363-I367 HydrophobicContact CG1-CD1 3.64Å; V363-I367 HydrophobicContact CG1-CG1 4.28Å; V363-I367 WeakPolarHBondContact O-CB 3.49Å; V363-I367 WeakPolarHBondContact O-CG1 3.45Å; V363-I367 PolarHBondContact O-N 2.5Å
364	G	80.9	Confident	81	Confident	0 Å²	0	22.8 Å²	22.8	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62	-42.4	177.4	0	0	0	0	0	112.2	Y101 V360 L361 T366 I367 N368 D457	Y101-G364 VanDerWaalsContact OH-CA 3.31Å; Y101-G364 WeakPolarHBondContact OH-CA 3.34Å; V360-G364 PolarHBondContact O-N 3.08Å; L361-G364 PolarHBondContact O-N 3.5Å; G364-T366 PolarHBondContact O-N 3.49Å; G364-I367 PolarHBondContact O-N 3.19Å; G364-N368 WeakPolarHBondContact O-CA 3.37Å; G364-N368 WeakPolarHBondContact O-CB 3.49Å; G364-N368 PolarHBondContact O-N 3.47Å; G364-D457 VanDerWaalsContact C-CG 3.48Å; G364-D457 WeakPolarHBondContact CA-OD1 3.43Å
365	A	74.1	Confident	82.2	Confident	4 Å²	4	17.3 Å²	17.3	3%	0.033	8%	0.076	C	C	.	.	H	α-helix	trans	-60.3	-15.9	-178.7	0	0	0	0	0	114.4	L361 M369 D457	L361-A365 WeakPolarHBondContact O-CB 3.48Å; L361-A365 PolarHBondContact O-N 3.17Å; A365-M369 WeakPolarHBondContact O-CE 3.32Å; A365-D457 WeakPolarHBondContact CA-OD2 3.33Å; A365-D457 PolarHBondContact N-OD2 3.26Å; A365-D457 VanDerWaalsContact N-OD2 3.16Å
366	T	70.9	Confident	83.1	Confident	13 Å²	13	13.6 Å²	13.6	8%	0.08	6%	0.062	C	C	.	.	H	α-helix	trans	-109.9	-40.6	174.7	58.2	0	0	0	0	112.9	V363 G364	V363-T366 PolarHBondContact O-N 3.27Å; V363-T366 PolarHBondContact O-OG1 2.95Å; V363-T366 VanDerWaalsContact O-OG1 3.08Å; G364-T366 PolarHBondContact O-N 3.49Å
367	I	80.3	Confident	83.8	Confident	15 Å²	15	13.6 Å²	13.6	8%	0.077	6%	0.062	C	C	.	.	H	α-helix	trans	-91.6	-38.7	-172.6	-60.6	-175.8	0	0	0	112.4	Y101 V363 G364 M369 I408	Y101-I367 HydrophobicContact CD2-CG2 4.4Å; V363-I367 HydrophobicContact CG1-CD1 3.64Å; V363-I367 HydrophobicContact CG1-CG1 4.28Å; V363-I367 WeakPolarHBondContact O-CB 3.49Å; V363-I367 WeakPolarHBondContact O-CG1 3.45Å; V363-I367 PolarHBondContact O-N 2.5Å; G364-I367 PolarHBondContact O-N 3.19Å; I367-M369 PolarHBondContact O-N 2.92Å; I367-I408 HydrophobicContact CB-CG2 4.49Å; I367-I408 HydrophobicContact CG1-CG2 4.44Å; I367-I408 HydrophobicContact CG2-CG1 4.24Å; I367-I408 HydrophobicContact CG2-CG2 4.08Å
368	N	89.4	Confident	84.9	Confident	1 Å²	1	13.6 Å²	13.6	1%	0.005	6%	0.062	C	C	.	.			trans	-97.2	89.5	-168.9	-176	55.8	0	0	0	111.4	Y101 T104 G364 D370 D457	Y101-N368 WeakPolarHBondContact CA-OD1 3.42Å; Y101-N368 HydrophobicContact CD1-CB 3.37Å; Y101-N368 WeakPolarHBondContact CD1-OD1 3.45Å; Y101-N368 HydrophobicContact CD2-CB 4Å; Y101-N368 HydrophobicContact CE1-CB 3.71Å; Y101-N368 HydrophobicContact CE2-CB 4.28Å; Y101-N368 HydrophobicContact CG-CB 3.53Å; T104-N368 PolarHBondContact OG1-OD1 3.44Å; G364-N368 WeakPolarHBondContact O-CA 3.37Å; G364-N368 WeakPolarHBondContact O-CB 3.49Å; G364-N368 PolarHBondContact O-N 3.47Å; N368-D370 PolarHBondContact OD1-OD1 3.49Å; N368-D457 VanDerWaalsContact CB-OD1 3.29Å; N368-D457 WeakPolarHBondContact CB-OD1 3.48Å; N368-D457 PolarHBondContact ND2-OD1 2.78Å
369	M	90.9	Very high	86	Confident	4 Å²	4	5.6 Å²	5.6	2%	0.02	3%	0.032	C	C	.	.			trans	-118.6	59.1	-177	-60.8	-149.2	176	0	0	113.1	A365 I367 G371 T372 A373 S407 A410 N453	A365-M369 WeakPolarHBondContact O-CE 3.32Å; I367-M369 PolarHBondContact O-N 2.92Å; M369-G371 VanDerWaalsContact C-N 3.26Å; M369-G371 PolarHBondContact O-N 3.39Å; M369-T372 PolarHBondContact O-N 3.24Å; M369-A373 PolarHBondContact O-N 3.12Å; M369-S407 WeakPolarHBondContact CG-O 3.2Å; M369-A410 WeakPolarHBondContact CE-O 3.42Å; M369-A410 HydrophobicContact SD-CB 3.57Å; M369-A410 VanDerWaalsContact SD-CB 3.57Å; M369-N453 WeakPolarHBondContact CA-OD1 3.41Å
370	D	95	Very high	87.2	Confident	0 Å²	0	4.4 Å²	4.4	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-48	-47	179.9	-60.2	-43.8	0	0	0	112.6	T104 T105 A108 H298 N368 A373 L374 N453	T104-D370 WeakPolarHBondContact CB-OD1 3.44Å; T104-D370 PolarHBondContact OG1-OD1 3.42Å; T105-D370 VanDerWaalsContact CA-OD1 3.31Å; T105-D370 WeakPolarHBondContact CA-OD1 3.43Å; T105-D370 PolarHBondContact N-OD1 3.36Å; T105-D370 PolarHBondContact OG1-OD1 3.31Å; A108-D370 HydrophobicContact CB-CB 4.07Å; A108-D370 WeakPolarHBondContact CB-O 3.49Å; H298-D370 IonicContact NE2-OD2 2.67Å; N368-D370 PolarHBondContact OD1-OD1 3.49Å; D370-A373 PolarHBondContact O-N 3.23Å; D370-L374 WeakPolarHBondContact O-CB 3.49Å; D370-L374 PolarHBondContact O-N 3.37Å; D370-N453 PolarHBondContact N-OD1 3.06Å
371	G	94.2	Very high	87.8	Confident	0 Å²	0	4.4 Å²	4.4	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-69.6	-33.3	-178.8	0	0	0	0	0	113.4	L295 M369 Y375 N453	L295-G371 VanDerWaalsContact CD2-CA 3.45Å; M369-G371 VanDerWaalsContact C-N 3.26Å; M369-G371 PolarHBondContact O-N 3.39Å; G371-Y375 VanDerWaalsContact O-CB 3.29Å; G371-Y375 WeakPolarHBondContact O-CB 3.23Å; G371-Y375 PolarHBondContact O-N 3.08Å; G371-N453 WeakPolarHBondContact CA-OD1 3.48Å; G371-N453 PolarHBondContact N-OD1 3.27Å
372	T	93	Very high	88.5	Confident	4 Å²	4	4.4 Å²	4.4	3%	0.025	3%	0.027	C	C	.	.	H	α-helix	trans	-70.2	-44.7	174.8	-55.1	0	0	0	0	110.7	M369 Y375 E376 A410 N453	M369-T372 PolarHBondContact O-N 3.24Å; T372-Y375 WeakPolarHBondContact O-CB 3.4Å; T372-Y375 PolarHBondContact O-N 3.24Å; T372-E376 HydrophobicContact CG2-CG 4.45Å; T372-E376 WeakPolarHBondContact CG2-OE1 3.35Å; T372-E376 WeakPolarHBondContact O-CB 3.24Å; T372-E376 WeakPolarHBondContact O-CG 3.32Å; T372-E376 PolarHBondContact O-N 3.08Å; T372-A410 HydrophobicContact CG2-CB 4.1Å; T372-N453 PolarHBondContact OG1-ND2 3.3Å
373	A	95.1	Very high	89.4	Confident	0 Å²	0	2.2 Å²	2.2	0%	0	1%	0.013	C	C	.	.	H	α-helix	trans	-63.8	-43.7	179.9	0	0	0	0	0	112.3	T105 V109 M369 D370 Y375 E376 A377	T105-A373 HydrophobicContact CG2-CB 3.47Å; T105-A373 VanDerWaalsContact CG2-CB 3.47Å; V109-A373 HydrophobicContact CG2-CB 3.47Å; V109-A373 VanDerWaalsContact CG2-CB 3.47Å; M369-A373 PolarHBondContact O-N 3.12Å; D370-A373 PolarHBondContact O-N 3.23Å; A373-Y375 VanDerWaalsContact C-N 3.34Å; A373-Y375 PolarHBondContact O-N 3.41Å; A373-E376 PolarHBondContact O-N 2.75Å; A373-A377 PolarHBondContact O-N 2.75Å
374	L	97.1	Very high	90.1	Very high	1 Å²	1	2 Å²	2	1%	0.005	1%	0.012	C	C	.	.	H	α-helix	trans	-58.8	-47	174.1	-176.5	152.8	0	0	0	111.1	A108 L111 L295 H298 D370 A377 V378	A108-L374 HydrophobicContact CB-CB 4.23Å; A108-L374 WeakPolarHBondContact O-CD1 3.38Å; L111-L374 HydrophobicContact CD2-CD1 4.17Å; L111-L374 HydrophobicContact CG-CD1 4.48Å; L295-L374 HydrophobicContact CD2-CD2 4.28Å; L295-L374 HydrophobicContact CG-CD2 4.35Å; H298-L374 HydrophobicContact CB-CD1 4.45Å; D370-L374 WeakPolarHBondContact O-CB 3.49Å; D370-L374 PolarHBondContact O-N 3.37Å; L374-A377 PolarHBondContact O-N 2.88Å; L374-V378 HydrophobicContact CD2-CG2 4.07Å; L374-V378 VanDerWaalsContact O-CG2 3.24Å; L374-V378 WeakPolarHBondContact O-CG2 3.46Å; L374-V378 PolarHBondContact O-N 2.99Å
375	Y	95.4	Very high	90.6	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-62.5	-43.3	178.6	158.2	-95.3	0	0	0	112.8	Y287 V291 G371 T372 A373 V378 A379 L418 M421 I438 D442 L445	Y287-Y375 VanDerWaalsContact OH-CD2 3.25Å; Y287-Y375 WeakPolarHBondContact OH-CD2 3.26Å; Y287-Y375 WeakPolarHBondContact OH-CE2 3.32Å; V291-Y375 HydrophobicContact CG1-CD2 4.28Å; V291-Y375 HydrophobicContact CG2-CD2 4.44Å; G371-Y375 VanDerWaalsContact O-CB 3.29Å; G371-Y375 WeakPolarHBondContact O-CB 3.23Å; G371-Y375 PolarHBondContact O-N 3.08Å; T372-Y375 WeakPolarHBondContact O-CB 3.4Å; T372-Y375 PolarHBondContact O-N 3.24Å; A373-Y375 VanDerWaalsContact C-N 3.34Å; A373-Y375 PolarHBondContact O-N 3.41Å; Y375-V378 PolarHBondContact O-N 3.31Å; Y375-A379 WeakPolarHBondContact O-CB 3.09Å; Y375-A379 PolarHBondContact O-N 3.05Å; Y375-L418 WeakPolarHBondContact OH-CD2 3.12Å; Y375-M421 HydrophobicContact CD1-CE 3.64Å; Y375-M421 HydrophobicContact CE1-CE 3.14Å; Y375-M421 HydrophobicContact CE2-CE 4.48Å; Y375-M421 HydrophobicContact CG-CE 4.47Å; Y375-I438 HydrophobicContact CE2-CG2 3.87Å; Y375-I438 WeakPolarHBondContact OH-CG2 3.39Å; Y375-D442 WeakPolarHBondContact CE2-OD1 3.44Å; Y375-D442 PolarHBondContact OH-OD1 2.91Å; Y375-L445 HydrophobicContact CD2-CD1 4.24Å; Y375-L445 HydrophobicContact CE2-CD1 4.08Å
376	E	93.8	Very high	91	Very high	0 Å²	0	4 Å²	4	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-60	-46	176.7	-79.3	176.4	-171.9	0	0	112.4	T372 A373 A379 A380 A403 A406 T420 M421 V424	T372-E376 HydrophobicContact CG2-CG 4.45Å; T372-E376 WeakPolarHBondContact CG2-OE1 3.35Å; T372-E376 WeakPolarHBondContact O-CB 3.24Å; T372-E376 WeakPolarHBondContact O-CG 3.32Å; T372-E376 PolarHBondContact O-N 3.08Å; A373-E376 PolarHBondContact O-N 2.75Å; E376-A379 PolarHBondContact O-N 3.09Å; E376-A380 VanDerWaalsContact O-CB 3.28Å; E376-A380 WeakPolarHBondContact O-CB 3.31Å; E376-A380 PolarHBondContact O-N 3.27Å; E376-A403 HydrophobicContact CB-CB 3.91Å; E376-A403 WeakPolarHBondContact OE2-CA 3.09Å; E376-A406 WeakPolarHBondContact OE2-CB 3.4Å; E376-T420 WeakPolarHBondContact OE1-CB 3.24Å; E376-T420 PolarHBondContact OE1-OG1 3.31Å; E376-M421 HydrophobicContact CB-CE 4.25Å; E376-M421 HydrophobicContact CB-SD 4.43Å; E376-M421 HydrophobicContact CG-CE 3.84Å; E376-M421 HydrophobicContact CG-SD 4.31Å; E376-V424 HydrophobicContact CB-CG2 4.27Å; E376-V424 HydrophobicContact CG-CG2 4.5Å
377	A	95.2	Very high	91.6	Very high	0 Å²	0	6.8 Å²	6.8	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-63.8	-45.5	177.3	0	0	0	0	0	112.1	V109 I113 A373 L374 I381 I399 A403	V109-A377 HydrophobicContact CG1-CB 4.02Å; I113-A377 HydrophobicContact CG1-CB 3.93Å; A373-A377 PolarHBondContact O-N 2.75Å; L374-A377 PolarHBondContact O-N 2.88Å; A377-I381 WeakPolarHBondContact O-CG1 3.44Å; A377-I381 PolarHBondContact O-N 3.22Å; A377-I399 HydrophobicContact CB-CG2 4.3Å; A377-A403 HydrophobicContact CB-CB 4.35Å
378	V	96.4	Very high	91.6	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-64.4	-44.8	178.7	173.4	0	0	0	0	111.1	G112 V116 Y287 T290 V291 L374 Y375 F382	G112-V378 WeakPolarHBondContact O-CG2 3.48Å; V116-V378 HydrophobicContact CB-CB 4.4Å; V116-V378 HydrophobicContact CB-CG1 4.04Å; V116-V378 HydrophobicContact CB-CG2 4.28Å; V116-V378 HydrophobicContact CG2-CG1 3.99Å; Y287-V378 HydrophobicContact CD2-CG1 4.05Å; Y287-V378 HydrophobicContact CE2-CG1 3.9Å; T290-V378 HydrophobicContact CG2-CG1 3.81Å; V291-V378 HydrophobicContact CG2-CB 4.1Å; V291-V378 HydrophobicContact CG2-CG1 3.59Å; L374-V378 HydrophobicContact CD2-CG2 4.07Å; L374-V378 VanDerWaalsContact O-CG2 3.24Å; L374-V378 WeakPolarHBondContact O-CG2 3.46Å; L374-V378 PolarHBondContact O-N 2.99Å; Y375-V378 PolarHBondContact O-N 3.31Å; V378-F382 WeakPolarHBondContact O-CB 3.37Å; V378-F382 PolarHBondContact O-N 3.46Å
379	A	93	Very high	91.2	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-65.6	-43.9	180	0	0	0	0	0	113.1	Y287 Y375 E376 I381 F382 I383 M421 I438	Y287-A379 HydrophobicContact CE2-CB 4.1Å; Y375-A379 WeakPolarHBondContact O-CB 3.09Å; Y375-A379 PolarHBondContact O-N 3.05Å; E376-A379 PolarHBondContact O-N 3.09Å; A379-I381 PolarHBondContact O-N 3.36Å; A379-F382 PolarHBondContact O-N 3.4Å; A379-I383 WeakPolarHBondContact O-CG1 3.29Å; A379-I383 PolarHBondContact O-N 2.94Å; A379-M421 HydrophobicContact CB-CE 3.2Å; A379-M421 HydrophobicContact CB-SD 3.46Å; A379-M421 WeakPolarHBondContact CB-SD 3.35Å; A379-I438 HydrophobicContact CB-CD1 3.53Å
380	A	92.4	Very high	90.6	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-61.9	-45.5	178.9	0	0	0	0	0	111.4	E376 I383 A384 I399 V424 L425 L430	E376-A380 VanDerWaalsContact O-CB 3.28Å; E376-A380 WeakPolarHBondContact O-CB 3.31Å; E376-A380 PolarHBondContact O-N 3.27Å; A380-I383 PolarHBondContact O-N 3.28Å; A380-A384 PolarHBondContact O-N 3.07Å; A380-I399 HydrophobicContact CB-CD1 4.27Å; A380-I399 HydrophobicContact CB-CG1 4.39Å; A380-I399 HydrophobicContact CB-CG2 4.05Å; A380-V424 HydrophobicContact CB-CG1 3.67Å; A380-L425 HydrophobicContact CB-CD2 4.08Å; A380-L430 WeakPolarHBondContact O-CD1 3.3Å
381	I	94	Very high	89.9	Confident	0 Å²	0	18.1 Å²	18.1	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-68.3	-38.1	176.9	-64.6	170.2	0	0	0	111	I113 V116 M117 A377 A379 A384 Q385 L391 I399	I113-I381 HydrophobicContact CB-CD1 4.17Å; I113-I381 HydrophobicContact CG1-CD1 3.83Å; I113-I381 HydrophobicContact CG2-CD1 3.96Å; V116-I381 HydrophobicContact CB-CG2 4.46Å; V116-I381 HydrophobicContact CG1-CB 3.7Å; V116-I381 HydrophobicContact CG1-CD1 3.55Å; V116-I381 HydrophobicContact CG1-CG1 4.2Å; V116-I381 HydrophobicContact CG1-CG2 3.67Å; V116-I381 HydrophobicContact CG2-CB 4.17Å; V116-I381 HydrophobicContact CG2-CG2 3.97Å; M117-I381 HydrophobicContact CG-CD1 4.43Å; M117-I381 HydrophobicContact SD-CG2 3.77Å; A377-I381 WeakPolarHBondContact O-CG1 3.44Å; A377-I381 PolarHBondContact O-N 3.22Å; A379-I381 PolarHBondContact O-N 3.36Å; I381-A384 WeakPolarHBondContact O-CB 3.43Å; I381-A384 PolarHBondContact O-N 3.24Å; I381-Q385 HydrophobicContact CG2-CG 4.4Å; I381-Q385 VanDerWaalsContact O-CG 3.3Å; I381-Q385 WeakPolarHBondContact O-CG 3.45Å; I381-Q385 PolarHBondContact O-N 3.02Å; I381-L391 HydrophobicContact CB-CD1 4.21Å; I381-L391 HydrophobicContact CG1-CD1 3.85Å; I381-L391 HydrophobicContact CG2-CD1 4.05Å; I381-I399 HydrophobicContact CG1-CD1 3.91Å
382	F	93.3	Very high	89.5	Confident	0 Å²	0	22 Å²	22	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62.2	-42.4	175.5	168.5	-103.5	0	0	0	112.4	V116 P121 K283 M284 Y287 V378 A379 A384 Q385 L386	V116-F382 HydrophobicContact CG2-CB 4.46Å; P121-F382 HydrophobicContact CB-CD2 3.82Å; P121-F382 HydrophobicContact CB-CE2 4.12Å; P121-F382 HydrophobicContact CG-CD2 3.78Å; K283-F382 HydrophobicContact CB-CE2 4.26Å; K283-F382 HydrophobicContact CB-CZ 4.4Å; M284-F382 HydrophobicContact CE-CD1 4.42Å; M284-F382 HydrophobicContact CE-CE1 3.14Å; M284-F382 HydrophobicContact CE-CE2 4.47Å; M284-F382 HydrophobicContact CE-CZ 3.16Å; Y287-F382 HydrophobicContact CD2-CB 3.84Å; Y287-F382 AromaticContact CD2-CD1 3.74Å; Y287-F382 HydrophobicContact CD2-CD1 3.74Å; Y287-F382 HydrophobicContact CD2-CD2 4.2Å; Y287-F382 HydrophobicContact CD2-CE1 4.4Å; Y287-F382 AromaticContact CD2-CG 3.62Å; Y287-F382 HydrophobicContact CD2-CG 3.62Å; Y287-F382 HydrophobicContact CE2-CB 4.31Å; Y287-F382 HydrophobicContact CE2-CD1 4.24Å; Y287-F382 HydrophobicContact CE2-CG 4.37Å; Y287-F382 HydrophobicContact CG-CD1 4.01Å; Y287-F382 HydrophobicContact CG-CD2 4.37Å; Y287-F382 HydrophobicContact CG-CE1 4.21Å; Y287-F382 HydrophobicContact CG-CG 4.09Å; Y287-F382 HydrophobicContact CG-CZ 4.44Å; V378-F382 WeakPolarHBondContact O-CB 3.37Å; V378-F382 PolarHBondContact O-N 3.46Å; A379-F382 PolarHBondContact O-N 3.4Å; F382-A384 VanDerWaalsContact C-N 3.34Å; F382-Q385 WeakPolarHBondContact O-CB 3.18Å; F382-Q385 PolarHBondContact O-N 2.83Å; F382-L386 HydrophobicContact CD1-CD1 4.09Å; F382-L386 HydrophobicContact CD1-CG 4.48Å; F382-L386 HydrophobicContact CD2-CG 4.46Å; F382-L386 HydrophobicContact CE1-CD1 3.27Å; F382-L386 HydrophobicContact CE1-CG 3.87Å; F382-L386 HydrophobicContact CE2-CD1 4.2Å; F382-L386 HydrophobicContact CE2-CD2 4.11Å; F382-L386 HydrophobicContact CE2-CG 3.91Å; F382-L386 HydrophobicContact CZ-CD1 3.35Å; F382-L386 HydrophobicContact CZ-CD2 3.85Å; F382-L386 HydrophobicContact CZ-CG 3.56Å; F382-L386 WeakPolarHBondContact O-CG 3.37Å; F382-L386 PolarHBondContact O-N 3.48Å
383	I	88.7	Confident	89	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-64.5	-39.3	174.1	-72.9	170.6	0	0	0	110.9	A379 A380 Q385 L386 N387 L425 D434 I438	A379-I383 WeakPolarHBondContact O-CG1 3.29Å; A379-I383 PolarHBondContact O-N 2.94Å; A380-I383 PolarHBondContact O-N 3.28Å; I383-Q385 VanDerWaalsContact C-N 3.33Å; I383-Q385 PolarHBondContact O-N 3.01Å; I383-L386 PolarHBondContact O-N 3.11Å; I383-N387 PolarHBondContact O-N 3.48Å; I383-N387 VanDerWaalsContact O-N 3.14Å; I383-N387 PolarHBondContact O-ND2 3.14Å; I383-L425 HydrophobicContact CB-CD2 4.13Å; I383-L425 HydrophobicContact CD1-CD1 3.66Å; I383-L425 HydrophobicContact CD1-CD2 3.94Å; I383-L425 HydrophobicContact CD1-CG 4.41Å; I383-L425 HydrophobicContact CG2-CD2 4.08Å; I383-D434 HydrophobicContact CD1-CB 4.35Å; I383-D434 HydrophobicContact CG1-CB 4.37Å; I383-D434 HydrophobicContact CG2-CB 3.91Å; I383-I438 HydrophobicContact CD1-CD1 3.57Å; I383-I438 HydrophobicContact CD1-CG1 4.35Å; I383-I438 HydrophobicContact CG1-CD1 3.97Å
384	A	89.3	Confident	88.1	Confident	0 Å²	0	28 Å²	28	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-59.7	-45.8	173.6	0	0	0	0	0	111.3	A380 I381 F382 L386 N387 D388 Y389 L391 L430	A380-A384 PolarHBondContact O-N 3.07Å; I381-A384 WeakPolarHBondContact O-CB 3.43Å; I381-A384 PolarHBondContact O-N 3.24Å; F382-A384 VanDerWaalsContact C-N 3.34Å; A384-L386 VanDerWaalsContact C-N 3.34Å; A384-L386 PolarHBondContact O-N 3.46Å; A384-N387 PolarHBondContact O-N 3.36Å; A384-D388 PolarHBondContact O-N 2.98Å; A384-Y389 WeakPolarHBondContact O-CB 3.38Å; A384-Y389 PolarHBondContact O-N 3.28Å; A384-L391 HydrophobicContact CB-CD1 3.61Å; A384-L391 HydrophobicContact CB-CD2 3.91Å; A384-L391 HydrophobicContact CB-CG 3.7Å; A384-L430 HydrophobicContact CB-CD1 3.86Å; A384-L430 HydrophobicContact CB-CD2 4.12Å
385	Q	90.1	Very high	87.3	Confident	22 Å²	22	28.3 Å²	28.3	10%	0.103	16%	0.162	C	C	.	.	H	α-helix	trans	-64	-35.8	176.5	-70.4	172.5	4.5	0	0	112.7	V116 K120 V123 I381 F382 I383 N387 D388	V116-Q385 PolarHBondContact O-NE2 3.42Å; K120-Q385 VanDerWaalsContact C-OE1 3.29Å; V123-Q385 HydrophobicContact CG1-CB 4.3Å; V123-Q385 HydrophobicContact CG1-CG 4.4Å; I381-Q385 HydrophobicContact CG2-CG 4.4Å; I381-Q385 VanDerWaalsContact O-CG 3.3Å; I381-Q385 WeakPolarHBondContact O-CG 3.45Å; I381-Q385 PolarHBondContact O-N 3.02Å; F382-Q385 WeakPolarHBondContact O-CB 3.18Å; F382-Q385 PolarHBondContact O-N 2.83Å; I383-Q385 VanDerWaalsContact C-N 3.33Å; I383-Q385 PolarHBondContact O-N 3.01Å; Q385-N387 VanDerWaalsContact C-N 3.3Å; Q385-N387 PolarHBondContact O-N 3.38Å; Q385-D388 PolarHBondContact O-N 3.16Å
386	L	84.1	Confident	86.9	Confident	25 Å²	25	30 Å²	30	13%	0.131	17%	0.171	C	C	.	.	H	α-helix	trans	-66.3	-31.8	176.5	-81.6	-178.3	0	0	0	113.3	K283 M284 F382 I383 A384 D388 L437	K283-L386 HydrophobicContact CB-CD2 4.3Å; K283-L386 HydrophobicContact CD-CD2 3.54Å; M284-L386 HydrophobicContact CE-CD1 4.3Å; F382-L386 HydrophobicContact CD1-CD1 4.09Å; F382-L386 HydrophobicContact CD1-CG 4.48Å; F382-L386 HydrophobicContact CD2-CG 4.46Å; F382-L386 HydrophobicContact CE1-CD1 3.27Å; F382-L386 HydrophobicContact CE1-CG 3.87Å; F382-L386 HydrophobicContact CE2-CD1 4.2Å; F382-L386 HydrophobicContact CE2-CD2 4.11Å; F382-L386 HydrophobicContact CE2-CG 3.91Å; F382-L386 HydrophobicContact CZ-CD1 3.35Å; F382-L386 HydrophobicContact CZ-CD2 3.85Å; F382-L386 HydrophobicContact CZ-CG 3.56Å; F382-L386 WeakPolarHBondContact O-CG 3.37Å; F382-L386 PolarHBondContact O-N 3.48Å; I383-L386 PolarHBondContact O-N 3.11Å; A384-L386 VanDerWaalsContact C-N 3.34Å; A384-L386 PolarHBondContact O-N 3.46Å; L386-D388 VanDerWaalsContact C-N 3.33Å; L386-L437 HydrophobicContact CD1-CD1 3.96Å
387	N	82	Confident	86.5	Confident	70 Å²	70	33.6 Å²	33.6	37%	0.374	19%	0.193	S	C	.	.	T	Hydrogen-bonded Turn	trans	-93.8	10.3	-179.5	-73.8	-66.4	0	0	0	113.2	I383 A384 Q385 Y389 D434	I383-N387 PolarHBondContact O-N 3.48Å; I383-N387 VanDerWaalsContact O-N 3.14Å; I383-N387 PolarHBondContact O-ND2 3.14Å; A384-N387 PolarHBondContact O-N 3.36Å; Q385-N387 VanDerWaalsContact C-N 3.3Å; Q385-N387 PolarHBondContact O-N 3.38Å; N387-Y389 PolarHBondContact O-N 2.85Å; N387-Y389 VanDerWaalsContact O-N 3.07Å; N387-D434 PolarHBondContact ND2-OD2 3.29Å; N387-D434 PolarHBondContact OD1-OD2 3.49Å
388	D	81.6	Confident	85.8	Confident	90 Å²	90	33.8 Å²	33.8	48%	0.481	19%	0.194	S	C	.	.	T	Hydrogen-bonded Turn	trans	51	33.5	-174.1	-58.9	-56.9	0	0	0	112.2	A384 Q385 L386 P390	A384-D388 PolarHBondContact O-N 2.98Å; Q385-D388 PolarHBondContact O-N 3.16Å; L386-D388 VanDerWaalsContact C-N 3.33Å; D388-P390 VanDerWaalsContact O-CD 3.25Å; D388-P390 WeakPolarHBondContact O-CD 3.47Å
389	Y	80.1	Confident	85.5	Confident	34 Å²	34	33.8 Å²	33.8	13%	0.133	19%	0.194	C	C	.	.			trans	-90	108.1	-177.5	-171.1	-87	0	0	0	109.5	T136 A384 N387 L391 Q395 L430	T136-Y389 HydrophobicContact CG2-CD2 4.31Å; T136-Y389 HydrophobicContact CG2-CE2 4.32Å; A384-Y389 WeakPolarHBondContact O-CB 3.38Å; A384-Y389 PolarHBondContact O-N 3.28Å; N387-Y389 PolarHBondContact O-N 2.85Å; N387-Y389 VanDerWaalsContact O-N 3.07Å; Y389-L391 HydrophobicContact CD1-CD2 3.99Å; Y389-L391 HydrophobicContact CE1-CD2 4.13Å; Y389-L391 PolarHBondContact O-N 3.04Å; Y389-Q395 PolarHBondContact OH-NE2 3.02Å; Y389-L430 HydrophobicContact CD1-CD2 3.9Å; Y389-L430 HydrophobicContact CD2-CD2 4.37Å; Y389-L430 HydrophobicContact CE1-CD2 4.48Å; Y389-L430 HydrophobicContact CG-CD2 3.83Å
390	P	78.2	Confident	85.4	Confident	99 Å²	99	34.9 Å²	34.9	64%	0.643	20%	0.201	S	C	*	.	P	Polyproline II helix	trans	-69.5	120.6	-179.5	28.7	-33.6	0	0	0	109.7	D388	D388-P390 VanDerWaalsContact O-CD 3.25Å; D388-P390 WeakPolarHBondContact O-CD 3.47Å
391	L	81.7	Confident	85.1	Confident	36 Å²	36	38.4 Å²	38.4	19%	0.188	22%	0.219	C	C	.	.	P	Polyproline II helix	trans	-86.2	123.1	176.5	-68.6	172.2	0	0	0	110.7	I381 A384 Y389 Q395 I396 I399	I381-L391 HydrophobicContact CB-CD1 4.21Å; I381-L391 HydrophobicContact CG1-CD1 3.85Å; I381-L391 HydrophobicContact CG2-CD1 4.05Å; A384-L391 HydrophobicContact CB-CD1 3.61Å; A384-L391 HydrophobicContact CB-CD2 3.91Å; A384-L391 HydrophobicContact CB-CG 3.7Å; Y389-L391 HydrophobicContact CD1-CD2 3.99Å; Y389-L391 HydrophobicContact CE1-CD2 4.13Å; Y389-L391 PolarHBondContact O-N 3.04Å; L391-Q395 HydrophobicContact CD2-CB 4.01Å; L391-I396 HydrophobicContact CB-CG1 4.16Å; L391-I399 HydrophobicContact CD1-CD1 4Å; L391-I399 HydrophobicContact CD2-CD1 4.17Å
392	D	83.9	Confident	84.5	Confident	82 Å²	82	38.8 Å²	38.8	44%	0.439	22%	0.222	S	C	.	.	P	Polyproline II helix	trans	-74.9	159	168	-178.3	40.6	0	0	0	111.4	T141 G394 Q395 I396	T141-D392 HydrophobicContact CG2-CB 4.11Å; T141-D392 VanDerWaalsContact CG2-OD2 3.32Å; T141-D392 WeakPolarHBondContact CG2-OD2 3.14Å; D392-G394 PolarHBondContact O-N 3.46Å; D392-G394 PolarHBondContact OD2-N 3.49Å; D392-Q395 WeakPolarHBondContact O-CB 3.08Å; D392-Q395 PolarHBondContact O-N 3.3Å; D392-I396 PolarHBondContact O-N 2.93Å
393	V	83.6	Confident	84.4	Confident	105 Å²	105	38.8 Å²	38.8	64%	0.636	22%	0.222	S	C	*	.	H	α-helix	trans	-54	-39.7	175.4	-179.9	0	0	0	0	110.8	Q395 I396 V397	V393-Q395 VanDerWaalsContact C-N 3.33Å; V393-Q395 PolarHBondContact O-N 2.86Å; V393-I396 PolarHBondContact O-N 3.26Å; V393-V397 WeakPolarHBondContact O-CG2 3.49Å; V393-V397 PolarHBondContact O-N 2.65Å
394	G	76	Confident	84.5	Confident	23 Å²	23	39.2 Å²	39.2	24%	0.237	23%	0.225	C	C	.	.	H	α-helix	trans	-60.9	-39.9	175.8	0	0	0	0	0	112.9	D392 V397 T398	D392-G394 PolarHBondContact O-N 3.46Å; D392-G394 PolarHBondContact OD2-N 3.49Å; G394-V397 PolarHBondContact O-N 3.42Å; G394-T398 PolarHBondContact O-N 3.04Å; G394-T398 PolarHBondContact O-OG1 3.23Å; G394-T398 VanDerWaalsContact O-OG1 3.05Å
395	Q	80.4	Confident	84	Confident	9 Å²	9	41.1 Å²	41.1	4%	0.042	24%	0.236	C	C	.	.	H	α-helix	trans	-70.3	-36.6	177.8	-66.5	174	-54.6	0	0	111.8	T141 Y389 L391 D392 V393 V397 T398 I399 V428	T141-Q395 HydrophobicContact CG2-CG 3.93Å; Y389-Q395 PolarHBondContact OH-NE2 3.02Å; L391-Q395 HydrophobicContact CD2-CB 4.01Å; D392-Q395 WeakPolarHBondContact O-CB 3.08Å; D392-Q395 PolarHBondContact O-N 3.3Å; V393-Q395 VanDerWaalsContact C-N 3.33Å; V393-Q395 PolarHBondContact O-N 2.86Å; Q395-V397 VanDerWaalsContact C-N 3.33Å; Q395-V397 PolarHBondContact O-N 3.27Å; Q395-T398 PolarHBondContact O-N 3.3Å; Q395-I399 WeakPolarHBondContact O-CG1 3.39Å; Q395-I399 PolarHBondContact O-N 2.78Å; Q395-V428 HydrophobicContact CB-CG1 4.25Å
396	I	87.8	Confident	83.5	Confident	34 Å²	34	40.2 Å²	40.2	17%	0.174	23%	0.232	C	C	.	.	H	α-helix	trans	-62.2	-42.7	174.7	-64.6	172.6	0	0	0	110.6	I113 M117 L391 D392 V393 I399 S400	I113-I396 HydrophobicContact CD1-CG2 4.2Å; I113-I396 HydrophobicContact CG2-CG2 3.75Å; M117-I396 HydrophobicContact CE-CD1 3.92Å; L391-I396 HydrophobicContact CB-CG1 4.16Å; D392-I396 PolarHBondContact O-N 2.93Å; V393-I396 PolarHBondContact O-N 3.26Å; I396-I399 PolarHBondContact O-N 2.96Å; I396-S400 PolarHBondContact O-N 3.22Å
397	V	85.8	Confident	83.6	Confident	76 Å²	76	39 Å²	39	46%	0.461	23%	0.226	S	C	.	.	H	α-helix	trans	-63.9	-42.9	174.7	174.1	0	0	0	0	110.9	V393 G394 Q395 I399 S400 I401	V393-V397 WeakPolarHBondContact O-CG2 3.49Å; V393-V397 PolarHBondContact O-N 2.65Å; G394-V397 PolarHBondContact O-N 3.42Å; Q395-V397 VanDerWaalsContact C-N 3.33Å; Q395-V397 PolarHBondContact O-N 3.27Å; V397-I399 PolarHBondContact O-N 3.27Å; V397-S400 WeakPolarHBondContact O-CB 3.23Å; V397-S400 PolarHBondContact O-N 2.88Å; V397-S400 VanDerWaalsContact O-N 3.15Å; V397-I401 HydrophobicContact CG1-CD1 3.89Å; V397-I401 HydrophobicContact CG1-CG1 4.48Å; V397-I401 WeakPolarHBondContact O-CG1 3.49Å; V397-I401 PolarHBondContact O-N 2.92Å
398	T	79.8	Confident	83.4	Confident	4 Å²	4	36.4 Å²	36.4	3%	0.025	21%	0.212	C	C	.	.	H	α-helix	trans	-59.6	-45.4	174.4	-60.2	0	0	0	0	111.5	L148 G394 Q395 S400 I401 T402 A427 V428	L148-T398 HydrophobicContact CD1-CG2 4.35Å; G394-T398 PolarHBondContact O-N 3.04Å; G394-T398 PolarHBondContact O-OG1 3.23Å; G394-T398 VanDerWaalsContact O-OG1 3.05Å; Q395-T398 PolarHBondContact O-N 3.3Å; T398-S400 VanDerWaalsContact C-N 3.29Å; T398-S400 PolarHBondContact O-N 3.5Å; T398-I401 PolarHBondContact O-N 3.5Å; T398-T402 HydrophobicContact CG2-CG2 4.04Å; T398-T402 VanDerWaalsContact O-CB 3.3Å; T398-T402 WeakPolarHBondContact O-CB 3.32Å; T398-T402 WeakPolarHBondContact O-CG2 3.32Å; T398-T402 PolarHBondContact O-N 3.15Å; T398-T402 PolarHBondContact O-OG1 3.14Å; T398-A427 HydrophobicContact CG2-CB 4.29Å; T398-V428 HydrophobicContact CG2-CG1 3.98Å
399	I	89.2	Confident	82.5	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-57.6	-44.7	173.9	-69.1	167.8	0	0	0	110.1	A377 A380 I381 L391 Q395 I396 V397 I401 T402 A403 V424 V428	A377-I399 HydrophobicContact CB-CG2 4.3Å; A380-I399 HydrophobicContact CB-CD1 4.27Å; A380-I399 HydrophobicContact CB-CG1 4.39Å; A380-I399 HydrophobicContact CB-CG2 4.05Å; I381-I399 HydrophobicContact CG1-CD1 3.91Å; L391-I399 HydrophobicContact CD1-CD1 4Å; L391-I399 HydrophobicContact CD2-CD1 4.17Å; Q395-I399 WeakPolarHBondContact O-CG1 3.39Å; Q395-I399 PolarHBondContact O-N 2.78Å; I396-I399 PolarHBondContact O-N 2.96Å; V397-I399 PolarHBondContact O-N 3.27Å; I399-I401 PolarHBondContact O-N 2.87Å; I399-T402 WeakPolarHBondContact CA-OG1 3.42Å; I399-T402 PolarHBondContact O-N 3.44Å; I399-T402 PolarHBondContact O-OG1 3.2Å; I399-A403 WeakPolarHBondContact O-CB 3.37Å; I399-A403 PolarHBondContact O-N 3.13Å; I399-V424 HydrophobicContact CG2-CG1 4.07Å; I399-V428 HydrophobicContact CD1-CG1 4.14Å; I399-V428 HydrophobicContact CD1-CG2 4.39Å; I399-V428 HydrophobicContact CG1-CB 4.43Å; I399-V428 HydrophobicContact CG1-CG1 3.49Å; I399-V428 VanDerWaalsContact CG1-CG1 3.49Å; I399-V428 HydrophobicContact CG1-CG2 4.21Å
400	S	91.7	Very high	81.9	Confident	23 Å²	23	30.7 Å²	30.7	16%	0.161	18%	0.184	C	C	.	.	H	α-helix	trans	-61.3	-47.4	-178.8	-172.7	0	0	0	0	112.6	V109 I396 V397 T398 T404	V109-S400 VanDerWaalsContact CG1-OG 3.3Å; V109-S400 WeakPolarHBondContact CG1-OG 3.18Å; I396-S400 PolarHBondContact O-N 3.22Å; V397-S400 WeakPolarHBondContact O-CB 3.23Å; V397-S400 PolarHBondContact O-N 2.88Å; V397-S400 VanDerWaalsContact O-N 3.15Å; T398-S400 VanDerWaalsContact C-N 3.29Å; T398-S400 PolarHBondContact O-N 3.5Å; S400-T404 PolarHBondContact O-N 3.28Å; S400-T404 PolarHBondContact O-OG1 3.49Å
401	I	86.3	Confident	81	Confident	74 Å²	74	26.3 Å²	26.3	38%	0.379	16%	0.157	S	C	.	.	H	α-helix	trans	-69.2	-46.7	-179.3	-65.7	170.5	0	0	0	109.9	L148 V397 T398 I399 T404 V405	L148-I401 HydrophobicContact CD1-CG2 4.45Å; V397-I401 HydrophobicContact CG1-CD1 3.89Å; V397-I401 HydrophobicContact CG1-CG1 4.48Å; V397-I401 WeakPolarHBondContact O-CG1 3.49Å; V397-I401 PolarHBondContact O-N 2.92Å; T398-I401 PolarHBondContact O-N 3.5Å; I399-I401 PolarHBondContact O-N 2.87Å; I401-T404 WeakPolarHBondContact O-CB 3.38Å; I401-T404 PolarHBondContact O-N 2.93Å; I401-V405 HydrophobicContact CG2-CG2 4.49Å; I401-V405 WeakPolarHBondContact O-CG2 3.04Å; I401-V405 PolarHBondContact O-N 3.34Å
402	T	82.1	Confident	80	Confident	8 Å²	8	24.8 Å²	24.8	5%	0.049	15%	0.15	C	C	.	.	H	α-helix	trans	-65.2	-42.1	-178.3	52.7	0	0	0	0	112.1	L148 T398 I399 T404 V405 A406 A427	L148-T402 HydrophobicContact CD1-CG2 3.27Å; L148-T402 HydrophobicContact CG-CG2 4.41Å; T398-T402 HydrophobicContact CG2-CG2 4.04Å; T398-T402 VanDerWaalsContact O-CB 3.3Å; T398-T402 WeakPolarHBondContact O-CB 3.32Å; T398-T402 WeakPolarHBondContact O-CG2 3.32Å; T398-T402 PolarHBondContact O-N 3.15Å; T398-T402 PolarHBondContact O-OG1 3.14Å; I399-T402 WeakPolarHBondContact CA-OG1 3.42Å; I399-T402 PolarHBondContact O-N 3.44Å; I399-T402 PolarHBondContact O-OG1 3.2Å; T402-T404 VanDerWaalsContact C-N 3.33Å; T402-T404 PolarHBondContact O-N 2.85Å; T402-V405 PolarHBondContact O-N 3.23Å; T402-A406 WeakPolarHBondContact O-CA 3.37Å; T402-A406 WeakPolarHBondContact O-CB 3.11Å; T402-A406 PolarHBondContact O-N 2.71Å; T402-A427 HydrophobicContact CG2-CB 3.59Å
403	A	90.8	Very high	79	Confident	0 Å²	0	21.7 Å²	21.7	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-62.9	-39.4	175.1	0	0	0	0	0	111.9	V109 E376 A377 I399 S407 V424	V109-A403 HydrophobicContact CG2-CB 4.31Å; E376-A403 HydrophobicContact CB-CB 3.91Å; E376-A403 WeakPolarHBondContact OE2-CA 3.09Å; A377-A403 HydrophobicContact CB-CB 4.35Å; I399-A403 WeakPolarHBondContact O-CB 3.37Å; I399-A403 PolarHBondContact O-N 3.13Å; A403-S407 VanDerWaalsContact O-CB 3.24Å; A403-S407 WeakPolarHBondContact O-CB 3.28Å; A403-S407 PolarHBondContact O-N 2.99Å; A403-S407 PolarHBondContact O-OG 3.07Å; A403-V424 HydrophobicContact CB-CG2 4.28Å
404	T	89.3	Confident	77.9	Confident	10 Å²	10	17.2 Å²	17.2	6%	0.061	11%	0.107	C	C	.	.	H	α-helix	trans	-61.4	-49.6	175.1	-56.6	0	0	0	0	110.6	F102 T105 I106 S400 I401 T402 S407	F102-T404 HydrophobicContact CD1-CG2 4.46Å; T105-T404 HydrophobicContact CG2-CG2 3.92Å; I106-T404 HydrophobicContact CG1-CG2 4.06Å; S400-T404 PolarHBondContact O-N 3.28Å; S400-T404 PolarHBondContact O-OG1 3.49Å; I401-T404 WeakPolarHBondContact O-CB 3.38Å; I401-T404 PolarHBondContact O-N 2.93Å; T402-T404 VanDerWaalsContact C-N 3.33Å; T402-T404 PolarHBondContact O-N 2.85Å; T404-S407 PolarHBondContact O-N 3.5Å; T404-S407 PolarHBondContact O-OG 2.73Å
405	V	80.6	Confident	77.4	Confident	39 Å²	39	16.9 Å²	16.9	24%	0.236	10%	0.1	C	C	.	.	H	α-helix	trans	-71.4	-38.7	-178	-178.6	0	0	0	0	112.2	L215 I401 T402 S407 I408 G409	L215-V405 HydrophobicContact CD1-CB 4.22Å; L215-V405 HydrophobicContact CD1-CG1 3.27Å; I401-V405 HydrophobicContact CG2-CG2 4.49Å; I401-V405 WeakPolarHBondContact O-CG2 3.04Å; I401-V405 PolarHBondContact O-N 3.34Å; T402-V405 PolarHBondContact O-N 3.23Å; V405-S407 VanDerWaalsContact C-N 3.3Å; V405-S407 PolarHBondContact O-N 3.06Å; V405-I408 WeakPolarHBondContact O-CB 3.44Å; V405-I408 PolarHBondContact O-N 3.22Å; V405-G409 PolarHBondContact O-N 3.39Å
406	A	79.6	Confident	76.5	Confident	3 Å²	3	17.1 Å²	17.1	3%	0.025	10%	0.103	C	C	.	.	H	α-helix	trans	-65.1	-36.1	178	0	0	0	0	0	111.3	E376 T402 I408 G409 A410 T420 I423 V424	E376-A406 WeakPolarHBondContact OE2-CB 3.4Å; T402-A406 WeakPolarHBondContact O-CA 3.37Å; T402-A406 WeakPolarHBondContact O-CB 3.11Å; T402-A406 PolarHBondContact O-N 2.71Å; A406-I408 VanDerWaalsContact C-N 3.31Å; A406-I408 PolarHBondContact O-N 3.12Å; A406-G409 CarbonylContact O-C 3.44Å; A406-G409 WeakPolarHBondContact O-CA 3.15Å; A406-G409 PolarHBondContact O-N 3.41Å; A406-A410 PolarHBondContact O-N 3.45Å; A406-T420 WeakPolarHBondContact O-CG2 3.14Å; A406-I423 HydrophobicContact CB-CD1 4.21Å; A406-V424 HydrophobicContact CB-CG2 3.97Å
407	S	84.9	Confident	75.6	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-63.3	-31.8	175.1	77.1	0	0	0	0	114	T105 M369 A403 T404 V405 G409 A410	T105-S407 WeakPolarHBondContact CG2-OG 3.26Å; M369-S407 WeakPolarHBondContact CG-O 3.2Å; A403-S407 VanDerWaalsContact O-CB 3.24Å; A403-S407 WeakPolarHBondContact O-CB 3.28Å; A403-S407 PolarHBondContact O-N 2.99Å; A403-S407 PolarHBondContact O-OG 3.07Å; T404-S407 PolarHBondContact O-N 3.5Å; T404-S407 PolarHBondContact O-OG 2.73Å; V405-S407 VanDerWaalsContact C-N 3.3Å; V405-S407 PolarHBondContact O-N 3.06Å; S407-G409 VanDerWaalsContact C-N 3.28Å; S407-A410 WeakPolarHBondContact O-CB 3.48Å; S407-A410 PolarHBondContact O-N 3.27Å
408	I	78.4	Confident	74.9	Confident	16 Å²	16	12.2 Å²	12.2	8%	0.082	8%	0.075	C	C	.	.	H	α-helix	trans	-68.4	-33	173.1	-62	167.2	0	0	0	110.7	M78 F102 I367 V405 A406 A410	M78-I408 VanDerWaalsContact CE-O 3.27Å; M78-I408 WeakPolarHBondContact CE-O 3.47Å; M78-I408 HydrophobicContact SD-CG2 4.3Å; F102-I408 HydrophobicContact CD1-CD1 4.34Å; F102-I408 HydrophobicContact CE1-CD1 3.43Å; F102-I408 VanDerWaalsContact CE1-CD1 3.43Å; F102-I408 HydrophobicContact CZ-CD1 3.53Å; I367-I408 HydrophobicContact CB-CG2 4.49Å; I367-I408 HydrophobicContact CG1-CG2 4.44Å; I367-I408 HydrophobicContact CG2-CG1 4.24Å; I367-I408 HydrophobicContact CG2-CG2 4.08Å; V405-I408 WeakPolarHBondContact O-CB 3.44Å; V405-I408 PolarHBondContact O-N 3.22Å; A406-I408 VanDerWaalsContact C-N 3.31Å; A406-I408 PolarHBondContact O-N 3.12Å; I408-A410 VanDerWaalsContact C-N 3.33Å
409	G	62.9	Low	74	Confident	1 Å²	1	13.2 Å²	13.2	1%	0.01	8%	0.081	C	C	.	.	H	α-helix	trans	-78.3	-15.2	176.6	0	0	0	0	0	114.7	I74 V405 A406 S407 A411	I74-G409 WeakPolarHBondContact CG1-O 3.44Å; V405-G409 PolarHBondContact O-N 3.39Å; A406-G409 CarbonylContact O-C 3.44Å; A406-G409 WeakPolarHBondContact O-CA 3.15Å; A406-G409 PolarHBondContact O-N 3.41Å; S407-G409 VanDerWaalsContact C-N 3.28Å; G409-A411 PolarHBondContact O-N 3.46Å
410	A	67.6	Low	73.5	Confident	2 Å²	2	13.5 Å²	13.5	2%	0.017	8%	0.082	C	C	.	.	S	Bend	trans	-71	120.2	175.9	0	0	0	0	0	107.8	M369 T372 A406 S407 I408 A416 T420	M369-A410 WeakPolarHBondContact CE-O 3.42Å; M369-A410 HydrophobicContact SD-CB 3.57Å; M369-A410 VanDerWaalsContact SD-CB 3.57Å; T372-A410 HydrophobicContact CG2-CB 4.1Å; A406-A410 PolarHBondContact O-N 3.45Å; S407-A410 WeakPolarHBondContact O-CB 3.48Å; S407-A410 PolarHBondContact O-N 3.27Å; I408-A410 VanDerWaalsContact C-N 3.33Å; A410-A416 HydrophobicContact CB-CB 4.19Å; A410-T420 HydrophobicContact CB-CG2 3.93Å
411	A	59.8	Low	73	Confident	8 Å²	8	12.4 Å²	12.4	7%	0.066	7%	0.074	C	C	.	.			trans	-70.1	153.5	172.7	0	0	0	0	0	110.1	L73 G409 V413 A416	L73-A411 HydrophobicContact CD1-CB 4.4Å; L73-A411 HydrophobicContact CD2-CB 3.24Å; L73-A411 HydrophobicContact CG-CB 3.53Å; G409-A411 PolarHBondContact O-N 3.46Å; A411-V413 HydrophobicContact CB-CG1 4.45Å; A411-V413 HydrophobicContact CB-CG2 4Å; A411-V413 PolarHBondContact O-N 3.14Å; A411-A416 WeakPolarHBondContact O-CB 3.31Å
412	G	60.7	Low	72.2	Confident	4 Å²	4	11.1 Å²	11.1	4%	0.041	7%	0.07	C	C	.	.	S	Bend	trans	-71.4	35.6	-178.3	0	0	0	0	0	114.1	S334 S335 S336	S334-G412 CarbonylContact C-O 3.14Å; S334-G412 WeakPolarHBondContact CA-O 3.43Å; S334-G412 WeakPolarHBondContact CB-O 3.22Å; S334-G412 PolarHBondContact OG-O 3.48Å; S335-G412 PolarHBondContact N-O 3.45Å; S335-G412 VanDerWaalsContact N-O 3.16Å; S336-G412 PolarHBondContact N-O 3.49Å; S336-G412 WeakPolarHBondContact OG-CA 3.33Å; S336-G412 PolarHBondContact OG-O 2.84Å
413	V	61.3	Low	71.5	Confident	16 Å²	16	12 Å²	12	10%	0.097	7%	0.074	C	C	.	.	S	Bend	trans	-110.5	154.3	-177.2	-59.3	0	0	0	0	110.6	L73 M250 V253 A411 A416	L73-V413 HydrophobicContact CD2-CB 4.4Å; L73-V413 HydrophobicContact CD2-CG1 3.8Å; L73-V413 HydrophobicContact CD2-CG2 3.7Å; M250-V413 HydrophobicContact CE-CG1 3.87Å; M250-V413 HydrophobicContact SD-CG1 3.45Å; M250-V413 WeakPolarHBondContact SD-CG1 3.35Å; V253-V413 HydrophobicContact CG1-CB 4.28Å; V253-V413 HydrophobicContact CG1-CG1 4.3Å; A411-V413 HydrophobicContact CB-CG1 4.45Å; A411-V413 HydrophobicContact CB-CG2 4Å; A411-V413 PolarHBondContact O-N 3.14Å; V413-A416 HydrophobicContact CG2-CB 3.9Å; V413-A416 WeakPolarHBondContact O-CB 3.28Å; V413-A416 PolarHBondContact O-N 3.49Å
414	P	61	Low	71.1	Confident	12 Å²	12	12 Å²	12	8%	0.078	7%	0.074	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.8	142.8	-178.2	-16.3	28.8	0	0	0	111.7	M257 S333 A416 D446	M257-P414 HydrophobicContact CE-CB 3.65Å; M257-P414 VanDerWaalsContact CE-CD 3.44Å; M257-P414 HydrophobicContact CE-CG 3.46Å; M257-P414 VanDerWaalsContact CE-CG 3.46Å; M257-P414 HydrophobicContact SD-CB 3.92Å; M257-P414 HydrophobicContact SD-CG 3.6Å; S333-P414 VanDerWaalsContact O-CA 3.28Å; S333-P414 WeakPolarHBondContact O-CA 3.32Å; S333-P414 WeakPolarHBondContact O-CB 3.5Å; S333-P414 VanDerWaalsContact O-CG 3.27Å; S333-P414 WeakPolarHBondContact O-CG 3.36Å; P414-A416 PolarHBondContact O-N 2.87Å; P414-D446 WeakPolarHBondContact CA-OD2 3.36Å
415	N	64.7	Low	70.6	Confident	16 Å²	16	11.5 Å²	11.5	9%	0.086	7%	0.071	C	C	.	.	T	Hydrogen-bonded Turn	trans	61.7	11.6	-179.1	-54.1	-41.9	0	0	0	115.8	L66 M260 G417 L418 D442 D446	L66-N415 HydrophobicContact CD1-CB 4.41Å; M260-N415 WeakPolarHBondContact CE-ND2 3.43Å; N415-G417 PolarHBondContact O-N 3.48Å; N415-L418 HydrophobicContact CB-CD1 4.26Å; N415-L418 PolarHBondContact O-N 3.34Å; N415-D442 PolarHBondContact OD1-OD2 2.67Å; N415-D446 PolarHBondContact N-OD1 2.92Å; N415-D446 PolarHBondContact N-OD2 3.26Å
416	A	62.3	Low	70	Confident	13 Å²	13	11.5 Å²	11.5	11%	0.107	7%	0.072	C	C	.	.	H	α-helix	trans	-57	-36.5	176.6	0	0	0	0	0	112.3	A410 A411 V413 P414 L418 V419 T420	A410-A416 HydrophobicContact CB-CB 4.19Å; A411-A416 WeakPolarHBondContact O-CB 3.31Å; V413-A416 HydrophobicContact CG2-CB 3.9Å; V413-A416 WeakPolarHBondContact O-CB 3.28Å; V413-A416 PolarHBondContact O-N 3.49Å; P414-A416 PolarHBondContact O-N 2.87Å; A416-L418 PolarHBondContact O-N 3.02Å; A416-V419 PolarHBondContact O-N 3.49Å; A416-V419 VanDerWaalsContact O-N 3.1Å; A416-T420 PolarHBondContact O-N 3.4Å; A416-T420 PolarHBondContact O-OG1 3.15Å
417	G	68.8	Low	69.3	Low	1 Å²	1	12.5 Å²	12.5	1%	0.01	8%	0.08	C	C	.	.	H	α-helix	trans	-59.4	-26.9	179.5	0	0	0	0	0	115	N415 V419 T420 M421	N415-G417 PolarHBondContact O-N 3.48Å; G417-V419 VanDerWaalsContact C-N 3.31Å; G417-V419 PolarHBondContact O-N 3.39Å; G417-T420 VanDerWaalsContact CA-OG1 3.27Å; G417-T420 WeakPolarHBondContact CA-OG1 3.11Å; G417-T420 PolarHBondContact O-OG1 2.98Å; G417-M421 WeakPolarHBondContact O-CB 3.29Å; G417-M421 PolarHBondContact O-N 2.97Å
418	L	70.1	Confident	68.7	Low	7 Å²	7	12.5 Å²	12.5	4%	0.037	8%	0.08	C	C	.	.	H	α-helix	trans	-71.3	-28.4	177.7	-79.4	167.8	0	0	0	112.8	Y375 N415 A416 M421 V435 I438 V439 D442	Y375-L418 WeakPolarHBondContact OH-CD2 3.12Å; N415-L418 HydrophobicContact CB-CD1 4.26Å; N415-L418 PolarHBondContact O-N 3.34Å; A416-L418 PolarHBondContact O-N 3.02Å; L418-M421 WeakPolarHBondContact O-CB 3.37Å; L418-V435 HydrophobicContact CD2-CG1 3.96Å; L418-I438 HydrophobicContact CD2-CB 4.49Å; L418-I438 HydrophobicContact CD2-CG2 4.26Å; L418-V439 HydrophobicContact CD1-CB 4.25Å; L418-V439 HydrophobicContact CD1-CG1 4.07Å; L418-V439 HydrophobicContact CD1-CG2 3.93Å; L418-V439 HydrophobicContact CD2-CG2 3.86Å; L418-V439 HydrophobicContact CG-CG2 4.47Å; L418-D442 HydrophobicContact CD1-CB 3.84Å; L418-D442 WeakPolarHBondContact CD1-OD2 3.04Å; L418-D442 HydrophobicContact CD2-CB 4.09Å; L418-D442 HydrophobicContact CG-CB 4.09Å; L418-D442 VanDerWaalsContact CG-OD2 3.23Å; L418-D442 WeakPolarHBondContact CG-OD2 3.45Å
419	V	62.4	Low	68.1	Low	25 Å²	25	12.5 Å²	12.5	15%	0.152	8%	0.084	C	C	.	.	H	α-helix	trans	-85.7	-38.9	-179.5	-179.8	0	0	0	0	111	I70 A416 G417 M421 V422	I70-V419 HydrophobicContact CD1-CB 3.37Å; I70-V419 HydrophobicContact CD1-CG1 3.4Å; I70-V419 VanDerWaalsContact CD1-CG1 3.4Å; I70-V419 HydrophobicContact CD1-CG2 3.12Å; I70-V419 HydrophobicContact CG2-CG1 4.29Å; A416-V419 PolarHBondContact O-N 3.49Å; A416-V419 VanDerWaalsContact O-N 3.1Å; G417-V419 VanDerWaalsContact C-N 3.31Å; G417-V419 PolarHBondContact O-N 3.39Å; V419-M421 PolarHBondContact O-N 3.15Å; V419-V422 WeakPolarHBondContact O-CB 3.33Å; V419-V422 PolarHBondContact O-N 3.49Å; V419-V422 VanDerWaalsContact O-N 3.12Å
420	T	77.4	Confident	68.6	Low	5 Å²	5	12.8 Å²	12.8	3%	0.031	9%	0.085	C	C	.	.	H	α-helix	trans	-65.6	-27	172.5	48.1	0	0	0	0	112	E376 A406 A410 A416 G417 V422 I423 V424	E376-T420 WeakPolarHBondContact OE1-CB 3.24Å; E376-T420 PolarHBondContact OE1-OG1 3.31Å; A406-T420 WeakPolarHBondContact O-CG2 3.14Å; A410-T420 HydrophobicContact CB-CG2 3.93Å; A416-T420 PolarHBondContact O-N 3.4Å; A416-T420 PolarHBondContact O-OG1 3.15Å; G417-T420 VanDerWaalsContact CA-OG1 3.27Å; G417-T420 WeakPolarHBondContact CA-OG1 3.11Å; G417-T420 PolarHBondContact O-OG1 2.98Å; T420-V422 PolarHBondContact O-N 3Å; T420-I423 HydrophobicContact CG2-CD1 4.16Å; T420-I423 VanDerWaalsContact O-CB 3.23Å; T420-I423 WeakPolarHBondContact O-CB 3.39Å; T420-I423 PolarHBondContact O-N 2.93Å; T420-V424 PolarHBondContact O-N 3.27Å
421	M	81.7	Confident	68.7	Low	0 Å²	0	15.3 Å²	15.3	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-52.8	-38.8	168.2	-167.5	65.3	62.3	0	0	113.8	Y375 E376 A379 G417 L418 V419 I423 V424 L425 V435	Y375-M421 HydrophobicContact CD1-CE 3.64Å; Y375-M421 HydrophobicContact CE1-CE 3.14Å; Y375-M421 HydrophobicContact CE2-CE 4.48Å; Y375-M421 HydrophobicContact CG-CE 4.47Å; E376-M421 HydrophobicContact CB-CE 4.25Å; E376-M421 HydrophobicContact CB-SD 4.43Å; E376-M421 HydrophobicContact CG-CE 3.84Å; E376-M421 HydrophobicContact CG-SD 4.31Å; A379-M421 HydrophobicContact CB-CE 3.2Å; A379-M421 HydrophobicContact CB-SD 3.46Å; A379-M421 WeakPolarHBondContact CB-SD 3.35Å; G417-M421 WeakPolarHBondContact O-CB 3.29Å; G417-M421 PolarHBondContact O-N 2.97Å; L418-M421 WeakPolarHBondContact O-CB 3.37Å; V419-M421 PolarHBondContact O-N 3.15Å; M421-I423 PolarHBondContact O-N 3.17Å; M421-V424 PolarHBondContact O-N 2.92Å; M421-V424 VanDerWaalsContact O-N 3.16Å; M421-L425 HydrophobicContact CG-CD1 4.11Å; M421-L425 HydrophobicContact CG-CG 4.3Å; M421-L425 WeakPolarHBondContact O-CG 3.41Å; M421-L425 PolarHBondContact O-N 3Å; M421-V435 HydrophobicContact CG-CG2 4.04Å
422	V	68.8	Low	69.1	Low	48 Å²	48	16.8 Å²	16.8	29%	0.291	11%	0.113	S	C	.	.	H	α-helix	trans	-60.8	-36.2	-178.9	177	0	0	0	0	110.2	V419 T420 L425 T426 A432 V435	V419-V422 WeakPolarHBondContact O-CB 3.33Å; V419-V422 PolarHBondContact O-N 3.49Å; V419-V422 VanDerWaalsContact O-N 3.12Å; T420-V422 PolarHBondContact O-N 3Å; V422-L425 PolarHBondContact O-N 3.16Å; V422-T426 HydrophobicContact CG1-CG2 4.17Å; V422-T426 WeakPolarHBondContact O-CB 3.39Å; V422-T426 VanDerWaalsContact O-CG2 3.26Å; V422-T426 WeakPolarHBondContact O-CG2 3.42Å; V422-T426 PolarHBondContact O-N 3.28Å; V422-T426 PolarHBondContact O-OG1 3.07Å; V422-A432 HydrophobicContact CG1-CB 4.01Å; V422-V435 HydrophobicContact CG2-CG2 4.33Å
423	I	68.8	Low	69.3	Low	26 Å²	26	20.1 Å²	20.1	13%	0.133	14%	0.136	C	C	.	.	H	α-helix	trans	-63.4	-47.5	177.6	-51.2	163.9	0	0	0	110.2	V214 A406 T420 M421 L425 T426 A427	V214-I423 HydrophobicContact CB-CD1 3.42Å; V214-I423 VanDerWaalsContact CB-CD1 3.42Å; V214-I423 HydrophobicContact CB-CG1 4.04Å; V214-I423 HydrophobicContact CG1-CD1 3.46Å; V214-I423 VanDerWaalsContact CG1-CD1 3.46Å; V214-I423 HydrophobicContact CG2-CD1 3.94Å; V214-I423 HydrophobicContact CG2-CG1 4.29Å; A406-I423 HydrophobicContact CB-CD1 4.21Å; T420-I423 HydrophobicContact CG2-CD1 4.16Å; T420-I423 VanDerWaalsContact O-CB 3.23Å; T420-I423 WeakPolarHBondContact O-CB 3.39Å; T420-I423 PolarHBondContact O-N 2.93Å; M421-I423 PolarHBondContact O-N 3.17Å; I423-L425 VanDerWaalsContact C-N 3.35Å; I423-L425 PolarHBondContact O-N 3.35Å; I423-T426 PolarHBondContact O-N 3.49Å; I423-T426 PolarHBondContact O-OG1 2.89Å; I423-T426 VanDerWaalsContact O-OG1 3.07Å; I423-A427 VanDerWaalsContact O-CB 3.3Å; I423-A427 WeakPolarHBondContact O-CB 3.39Å; I423-A427 PolarHBondContact O-N 3Å
424	V	82.9	Confident	69.7	Low	0 Å²	0	20.8 Å²	20.8	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-63.6	-43.7	-178.4	-177.8	0	0	0	0	110.2	E376 A380 I399 A403 A406 T420 M421 A427 V428	E376-V424 HydrophobicContact CB-CG2 4.27Å; E376-V424 HydrophobicContact CG-CG2 4.5Å; A380-V424 HydrophobicContact CB-CG1 3.67Å; I399-V424 HydrophobicContact CG2-CG1 4.07Å; A403-V424 HydrophobicContact CB-CG2 4.28Å; A406-V424 HydrophobicContact CB-CG2 3.97Å; T420-V424 PolarHBondContact O-N 3.27Å; M421-V424 PolarHBondContact O-N 2.92Å; M421-V424 VanDerWaalsContact O-N 3.16Å; V424-A427 PolarHBondContact O-N 3.45Å; V424-V428 WeakPolarHBondContact O-CG2 3.28Å; V424-V428 PolarHBondContact O-N 3.04Å
425	L	78.2	Confident	70.2	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-66.9	-44.5	178	-67	176.2	0	0	0	112.7	A380 I383 M421 V422 I423 A427 V428 G429 L430 V435	A380-L425 HydrophobicContact CB-CD2 4.08Å; I383-L425 HydrophobicContact CB-CD2 4.13Å; I383-L425 HydrophobicContact CD1-CD1 3.66Å; I383-L425 HydrophobicContact CD1-CD2 3.94Å; I383-L425 HydrophobicContact CD1-CG 4.41Å; I383-L425 HydrophobicContact CG2-CD2 4.08Å; M421-L425 HydrophobicContact CG-CD1 4.11Å; M421-L425 HydrophobicContact CG-CG 4.3Å; M421-L425 WeakPolarHBondContact O-CG 3.41Å; M421-L425 PolarHBondContact O-N 3Å; V422-L425 PolarHBondContact O-N 3.16Å; I423-L425 VanDerWaalsContact C-N 3.35Å; I423-L425 PolarHBondContact O-N 3.35Å; L425-A427 VanDerWaalsContact C-N 3.28Å; L425-A427 PolarHBondContact O-N 3.26Å; L425-V428 WeakPolarHBondContact O-CG2 3.4Å; L425-V428 PolarHBondContact O-N 3.49Å; L425-G429 PolarHBondContact O-N 2.86Å; L425-L430 HydrophobicContact CB-CB 4.17Å; L425-L430 HydrophobicContact CD2-CB 3.84Å; L425-L430 HydrophobicContact CD2-CD1 3.7Å; L425-L430 HydrophobicContact CD2-CG 4.45Å; L425-L430 PolarHBondContact O-N 3.39Å; L425-V435 HydrophobicContact CD1-CG2 3.22Å
426	T	66.8	Low	70.3	Confident	39 Å²	39	22.2 Å²	22.2	24%	0.239	15%	0.148	C	C	.	.	H	α-helix	trans	-65.6	-34.5	179.6	53.9	0	0	0	0	111.7	V422 I423 V428 G429	V422-T426 HydrophobicContact CG1-CG2 4.17Å; V422-T426 WeakPolarHBondContact O-CB 3.39Å; V422-T426 VanDerWaalsContact O-CG2 3.26Å; V422-T426 WeakPolarHBondContact O-CG2 3.42Å; V422-T426 PolarHBondContact O-N 3.28Å; V422-T426 PolarHBondContact O-OG1 3.07Å; I423-T426 PolarHBondContact O-N 3.49Å; I423-T426 PolarHBondContact O-OG1 2.89Å; I423-T426 VanDerWaalsContact O-OG1 3.07Å; T426-V428 VanDerWaalsContact C-N 3.29Å; T426-V428 PolarHBondContact O-N 3.36Å; T426-G429 PolarHBondContact O-N 2.86Å; T426-G429 VanDerWaalsContact O-N 3.12Å
427	A	66.3	Low	70.6	Confident	24 Å²	24	23.7 Å²	23.7	20%	0.198	15%	0.154	C	C	.	.	H	α-helix	trans	-63.4	-32.7	178.1	0	0	0	0	0	113.3	T144 T398 T402 I423 V424 L425	T144-A427 WeakPolarHBondContact CB-O 3.31Å; T398-A427 HydrophobicContact CG2-CB 4.29Å; T402-A427 HydrophobicContact CG2-CB 3.59Å; I423-A427 VanDerWaalsContact O-CB 3.3Å; I423-A427 WeakPolarHBondContact O-CB 3.39Å; I423-A427 PolarHBondContact O-N 3Å; V424-A427 PolarHBondContact O-N 3.45Å; L425-A427 VanDerWaalsContact C-N 3.28Å; L425-A427 PolarHBondContact O-N 3.26Å
428	V	71.1	Confident	71.1	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-96.4	0.2	173.5	-67.5	0	0	0	0	114.5	Q395 T398 I399 V424 L425 T426 L430	Q395-V428 HydrophobicContact CB-CG1 4.25Å; T398-V428 HydrophobicContact CG2-CG1 3.98Å; I399-V428 HydrophobicContact CD1-CG1 4.14Å; I399-V428 HydrophobicContact CD1-CG2 4.39Å; I399-V428 HydrophobicContact CG1-CB 4.43Å; I399-V428 HydrophobicContact CG1-CG1 3.49Å; I399-V428 VanDerWaalsContact CG1-CG1 3.49Å; I399-V428 HydrophobicContact CG1-CG2 4.21Å; V424-V428 WeakPolarHBondContact O-CG2 3.28Å; V424-V428 PolarHBondContact O-N 3.04Å; L425-V428 WeakPolarHBondContact O-CG2 3.4Å; L425-V428 PolarHBondContact O-N 3.49Å; T426-V428 VanDerWaalsContact C-N 3.29Å; T426-V428 PolarHBondContact O-N 3.36Å; V428-L430 HydrophobicContact CG2-CB 4.29Å; V428-L430 HydrophobicContact CG2-CD1 3.59Å; V428-L430 HydrophobicContact CG2-CG 3.78Å
429	G	65.8	Low	71.1	Confident	16 Å²	16	24.2 Å²	24.2	17%	0.165	16%	0.157	C	C	.	.	T	Hydrogen-bonded Turn	trans	80.1	18.7	177.5	0	0	0	0	0	114.8	L425 T426	L425-G429 PolarHBondContact O-N 2.86Å; T426-G429 PolarHBondContact O-N 2.86Å; T426-G429 VanDerWaalsContact O-N 3.12Å
430	L	74.5	Confident	71.4	Confident	7 Å²	7	24.1 Å²	24.1	4%	0.037	16%	0.159	C	C	.	.			trans	-80.5	149	174.8	-70.2	169.9	0	0	0	111.5	A380 A384 Y389 L425 V428 A432	A380-L430 WeakPolarHBondContact O-CD1 3.3Å; A384-L430 HydrophobicContact CB-CD1 3.86Å; A384-L430 HydrophobicContact CB-CD2 4.12Å; Y389-L430 HydrophobicContact CD1-CD2 3.9Å; Y389-L430 HydrophobicContact CD2-CD2 4.37Å; Y389-L430 HydrophobicContact CE1-CD2 4.48Å; Y389-L430 HydrophobicContact CG-CD2 3.83Å; L425-L430 HydrophobicContact CB-CB 4.17Å; L425-L430 HydrophobicContact CD2-CB 3.84Å; L425-L430 HydrophobicContact CD2-CD1 3.7Å; L425-L430 HydrophobicContact CD2-CG 4.45Å; L425-L430 PolarHBondContact O-N 3.39Å; V428-L430 HydrophobicContact CG2-CB 4.29Å; V428-L430 HydrophobicContact CG2-CD1 3.59Å; V428-L430 HydrophobicContact CG2-CG 3.78Å; L430-A432 PolarHBondContact O-N 3.46Å
431	P	70	Confident	71.3	Confident	55 Å²	55	25.1 Å²	25.1	36%	0.357	17%	0.165	S	C	.	.			trans	-69.2	123.1	179.7	27.8	-33.9	0	0	0	111.8	S433 D434	P431-S433 PolarHBondContact O-N 3.25Å; P431-D434 WeakPolarHBondContact CG-OD2 3.39Å; P431-D434 PolarHBondContact O-N 2.84Å
432	A	67.6	Low	71.3	Confident	39 Å²	39	25.1 Å²	25.1	32%	0.322	17%	0.165	S	C	.	.	G	3₁₀ helix	trans	-71.9	-10.6	179.4	0	0	0	0	0	114	V422 L430 D434 V435	V422-A432 HydrophobicContact CG1-CB 4.01Å; L430-A432 PolarHBondContact O-N 3.46Å; A432-D434 PolarHBondContact O-N 2.98Å; A432-V435 WeakPolarHBondContact O-CB 3.47Å; A432-V435 WeakPolarHBondContact O-CG2 3.43Å; A432-V435 PolarHBondContact O-N 3.47Å
433	S	64.3	Low	71.5	Confident	74 Å²	74	25 Å²	25	52%	0.517	16%	0.16	S	C	.	.	G	3₁₀ helix	trans	-58.3	-31	174.1	47.6	0	0	0	0	112.3	P431 V435 T436	P431-S433 PolarHBondContact O-N 3.25Å; S433-V435 VanDerWaalsContact C-N 3.28Å; S433-V435 PolarHBondContact O-N 3.27Å; S433-T436 WeakPolarHBondContact O-CB 3.5Å; S433-T436 VanDerWaalsContact O-CG2 3.32Å; S433-T436 WeakPolarHBondContact O-CG2 3.32Å; S433-T436 PolarHBondContact O-N 3.11Å; S433-T436 PolarHBondContact O-OG1 2.93Å
434	D	70.5	Confident	72.1	Confident	29 Å²	29	25.9 Å²	25.9	16%	0.155	16%	0.164	C	C	.	.	G	3₁₀ helix	trans	-82.8	-12	-169.4	-58.6	-5.4	0	0	0	112.2	I383 N387 P431 A432 T436 L437	I383-D434 HydrophobicContact CD1-CB 4.35Å; I383-D434 HydrophobicContact CG1-CB 4.37Å; I383-D434 HydrophobicContact CG2-CB 3.91Å; N387-D434 PolarHBondContact ND2-OD2 3.29Å; N387-D434 PolarHBondContact OD1-OD2 3.49Å; P431-D434 WeakPolarHBondContact CG-OD2 3.39Å; P431-D434 PolarHBondContact O-N 2.84Å; A432-D434 PolarHBondContact O-N 2.98Å; D434-T436 PolarHBondContact O-N 3.24Å; D434-T436 VanDerWaalsContact O-N 3.12Å; D434-L437 WeakPolarHBondContact O-CB 3.37Å; D434-L437 PolarHBondContact O-N 2.88Å
435	V	72.1	Confident	72.4	Confident	8 Å²	8	25.9 Å²	25.9	5%	0.048	16%	0.164	C	C	.	.	H	α-helix	trans	-52.6	-32.8	166	178.4	0	0	0	0	110.4	L418 M421 V422 L425 A432 S433 L437 I438 V439	L418-V435 HydrophobicContact CD2-CG1 3.96Å; M421-V435 HydrophobicContact CG-CG2 4.04Å; V422-V435 HydrophobicContact CG2-CG2 4.33Å; L425-V435 HydrophobicContact CD1-CG2 3.22Å; A432-V435 WeakPolarHBondContact O-CB 3.47Å; A432-V435 WeakPolarHBondContact O-CG2 3.43Å; A432-V435 PolarHBondContact O-N 3.47Å; S433-V435 VanDerWaalsContact C-N 3.28Å; S433-V435 PolarHBondContact O-N 3.27Å; V435-L437 PolarHBondContact O-N 3.26Å; V435-L437 VanDerWaalsContact O-N 3.16Å; V435-I438 WeakPolarHBondContact O-CA 3.19Å; V435-I438 WeakPolarHBondContact O-CB 3.3Å; V435-I438 PolarHBondContact O-N 3.15Å; V435-V439 HydrophobicContact CG1-CG2 4.35Å; V435-V439 WeakPolarHBondContact O-CG2 3.49Å; V435-V439 PolarHBondContact O-N 3.23Å; V435-V439 VanDerWaalsContact O-N 3.08Å
436	T	65.4	Low	72.8	Confident	51 Å²	51	26.1 Å²	26.1	31%	0.313	17%	0.166	S	C	.	.	H	α-helix	trans	-60.6	-26.2	-178.8	63.9	0	0	0	0	113.7	K271 S433 D434	K271-T436 PolarHBondContact NZ-OG1 2.96Å; S433-T436 WeakPolarHBondContact O-CB 3.5Å; S433-T436 VanDerWaalsContact O-CG2 3.32Å; S433-T436 WeakPolarHBondContact O-CG2 3.32Å; S433-T436 PolarHBondContact O-N 3.11Å; S433-T436 PolarHBondContact O-OG1 2.93Å; D434-T436 PolarHBondContact O-N 3.24Å; D434-T436 VanDerWaalsContact O-N 3.12Å
437	L	70	Confident	73.6	Confident	43 Å²	43	25.2 Å²	25.2	23%	0.225	16%	0.158	C	C	.	.	H	α-helix	trans	-67.6	-39.7	173	-63.5	170.1	0	0	0	111	M284 L386 D434 V435	M284-L437 HydrophobicContact CE-CB 4.13Å; M284-L437 HydrophobicContact SD-CB 4.24Å; L386-L437 HydrophobicContact CD1-CD1 3.96Å; D434-L437 WeakPolarHBondContact O-CB 3.37Å; D434-L437 PolarHBondContact O-N 2.88Å; V435-L437 PolarHBondContact O-N 3.26Å; V435-L437 VanDerWaalsContact O-N 3.16Å
438	I	78.4	Confident	74.9	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-73	-34.2	-178.7	-55.2	-172.9	0	0	0	111.3	Y287 Y375 A379 I383 L418 V435 A440 V441 D442	Y287-I438 HydrophobicContact CE1-CG2 4.03Å; Y287-I438 WeakPolarHBondContact OH-CG2 3.46Å; Y375-I438 HydrophobicContact CE2-CG2 3.87Å; Y375-I438 WeakPolarHBondContact OH-CG2 3.39Å; A379-I438 HydrophobicContact CB-CD1 3.53Å; I383-I438 HydrophobicContact CD1-CD1 3.57Å; I383-I438 HydrophobicContact CD1-CG1 4.35Å; I383-I438 HydrophobicContact CG1-CD1 3.97Å; L418-I438 HydrophobicContact CD2-CB 4.49Å; L418-I438 HydrophobicContact CD2-CG2 4.26Å; V435-I438 WeakPolarHBondContact O-CA 3.19Å; V435-I438 WeakPolarHBondContact O-CB 3.3Å; V435-I438 PolarHBondContact O-N 3.15Å; I438-A440 PolarHBondContact O-N 2.93Å; I438-V441 HydrophobicContact CG2-CG2 4.49Å; I438-V441 VanDerWaalsContact O-CG2 3.24Å; I438-V441 WeakPolarHBondContact O-CG2 3.46Å; I438-V441 PolarHBondContact O-N 3.28Å; I438-D442 WeakPolarHBondContact O-CB 3.26Å; I438-D442 PolarHBondContact O-N 2.88Å
439	V	70.2	Confident	76	Confident	20 Å²	20	27.3 Å²	27.3	12%	0.121	16%	0.162	C	C	.	.	H	α-helix	trans	-52.6	-34.8	178.2	-177.1	0	0	0	0	111.9	M63 L267 L418 V435 V441 D442	M63-V439 HydrophobicContact CE-CG2 4.11Å; M63-V439 HydrophobicContact SD-CG1 4.22Å; L267-V439 HydrophobicContact CD1-CG1 3.66Å; L267-V439 HydrophobicContact CD2-CB 3.9Å; L267-V439 HydrophobicContact CD2-CG1 3.48Å; L267-V439 VanDerWaalsContact CD2-CG1 3.48Å; L267-V439 HydrophobicContact CG-CG1 4.23Å; L418-V439 HydrophobicContact CD1-CB 4.25Å; L418-V439 HydrophobicContact CD1-CG1 4.07Å; L418-V439 HydrophobicContact CD1-CG2 3.93Å; L418-V439 HydrophobicContact CD2-CG2 3.86Å; L418-V439 HydrophobicContact CG-CG2 4.47Å; V435-V439 HydrophobicContact CG1-CG2 4.35Å; V435-V439 WeakPolarHBondContact O-CG2 3.49Å; V435-V439 PolarHBondContact O-N 3.23Å; V435-V439 VanDerWaalsContact O-N 3.08Å; V439-V441 VanDerWaalsContact C-N 3.28Å; V439-V441 PolarHBondContact O-N 3.45Å; V439-D442 PolarHBondContact O-N 3.26Å
440	A	68.3	Low	77.1	Confident	22 Å²	22	26.9 Å²	26.9	18%	0.182	16%	0.156	C	C	.	.	H	α-helix	trans	-66.3	-27.2	-178.4	0	0	0	0	0	114	I268 I438 W443	I268-A440 HydrophobicContact CG1-CB 4.12Å; I438-A440 PolarHBondContact O-N 2.93Å; A440-W443 PolarHBondContact O-NE1 2.9Å
441	V	75.7	Confident	78	Confident	27 Å²	27	28.6 Å²	28.6	16%	0.164	17%	0.165	C	C	.	.	H	α-helix	trans	-106.4	-15.3	179.5	-64	0	0	0	0	112.8	Y287 I438 V439 W443 L444 L445	Y287-V441 HydrophobicContact CD1-CG2 4.16Å; Y287-V441 HydrophobicContact CE1-CG2 3.84Å; I438-V441 HydrophobicContact CG2-CG2 4.49Å; I438-V441 VanDerWaalsContact O-CG2 3.24Å; I438-V441 WeakPolarHBondContact O-CG2 3.46Å; I438-V441 PolarHBondContact O-N 3.28Å; V439-V441 VanDerWaalsContact C-N 3.28Å; V439-V441 PolarHBondContact O-N 3.45Å; V441-W443 VanDerWaalsContact C-N 3.27Å; V441-W443 PolarHBondContact O-N 3.48Å; V441-L444 PolarHBondContact O-N 3.25Å; V441-L445 HydrophobicContact CG2-CD1 4.28Å; V441-L445 PolarHBondContact O-N 3.49Å
442	D	81.7	Confident	79.3	Confident	0 Å²	0	26.2 Å²	26.2	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-63	-31.2	-174	-170.3	50.3	0	0	0	113.1	Y375 N415 L418 I438 V439 L444 L445 D446 R449	Y375-D442 WeakPolarHBondContact CE2-OD1 3.44Å; Y375-D442 PolarHBondContact OH-OD1 2.91Å; N415-D442 PolarHBondContact OD1-OD2 2.67Å; L418-D442 HydrophobicContact CD1-CB 3.84Å; L418-D442 WeakPolarHBondContact CD1-OD2 3.04Å; L418-D442 HydrophobicContact CD2-CB 4.09Å; L418-D442 HydrophobicContact CG-CB 4.09Å; L418-D442 VanDerWaalsContact CG-OD2 3.23Å; L418-D442 WeakPolarHBondContact CG-OD2 3.45Å; I438-D442 WeakPolarHBondContact O-CB 3.26Å; I438-D442 PolarHBondContact O-N 2.88Å; V439-D442 PolarHBondContact O-N 3.26Å; D442-L444 PolarHBondContact O-N 3.01Å; D442-L445 PolarHBondContact O-N 3.05Å; D442-D446 WeakPolarHBondContact O-CB 3.3Å; D442-D446 PolarHBondContact O-N 3.25Å; D442-R449 VanDerWaalsContact CG-NH2 3.28Å; D442-R449 IonicContact OD1-CZ 3.27Å; D442-R449 IonicContact OD1-NE 3.48Å; D442-R449 PolarHBondContact OD1-NE 3.12Å; D442-R449 IonicContact OD1-NH2 2.93Å; D442-R449 PolarHBondContact OD1-NH2 2.71Å; D442-R449 IonicContact OD2-NH2 2.8Å; D442-R449 PolarHBondContact OD2-NH2 3.14Å
443	W	73.4	Confident	80.6	Confident	46 Å²	46	24.5 Å²	24.5	17%	0.174	14%	0.135	C	C	.	.	H	α-helix	trans	-54.5	-27.2	177.6	75.2	-89.8	0	0	0	113.7	T27 V28 V31 I264 A440 V441 R447	T27-W443 HydrophobicContact CG2-CB 4.47Å; T27-W443 HydrophobicContact CG2-CE3 4.45Å; V28-W443 HydrophobicContact CG2-CH2 4.34Å; V28-W443 HydrophobicContact CG2-CZ3 3.79Å; V31-W443 HydrophobicContact CB-CD2 4.44Å; V31-W443 HydrophobicContact CB-CZ2 4.07Å; V31-W443 HydrophobicContact CG1-CZ2 3.62Å; V31-W443 HydrophobicContact CG2-CD2 3.5Å; V31-W443 VanDerWaalsContact CG2-CD2 3.5Å; V31-W443 VanDerWaalsContact CG2-CE2 3.43Å; V31-W443 HydrophobicContact CG2-CE3 4.16Å; V31-W443 HydrophobicContact CG2-CG 3.65Å; V31-W443 HydrophobicContact CG2-CZ2 4.03Å; I264-W443 HydrophobicContact CD1-CB 4.3Å; A440-W443 PolarHBondContact O-NE1 2.9Å; V441-W443 VanDerWaalsContact C-N 3.27Å; V441-W443 PolarHBondContact O-N 3.48Å; W443-R447 WeakPolarHBondContact O-CG 3.33Å; W443-R447 PolarHBondContact O-NE 3.05Å
444	L	80.4	Confident	82	Confident	43 Å²	43	21.1 Å²	21.1	23%	0.225	11%	0.111	C	C	.	.	H	α-helix	trans	-88.4	-47.2	175.9	179.7	63.1	0	0	0	110.6	M288 V441 D442 D446 R447 F448	M288-L444 HydrophobicContact SD-CD2 3.66Å; V441-L444 PolarHBondContact O-N 3.25Å; D442-L444 PolarHBondContact O-N 3.01Å; L444-D446 PolarHBondContact O-N 3.4Å; L444-R447 WeakPolarHBondContact O-CB 3.42Å; L444-R447 PolarHBondContact O-N 3.4Å; L444-F448 HydrophobicContact CD1-CE2 3.85Å; L444-F448 HydrophobicContact CG-CE2 4.19Å; L444-F448 WeakPolarHBondContact O-CD2 3.45Å
445	L	89.9	Confident	83.3	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-62.4	-43.7	-177.5	-64.1	178.9	0	0	0	111.3	Y287 M288 V291 L292 Y375 V441 D442 R447 F448 R449	Y287-L445 HydrophobicContact CE1-CD1 3.62Å; M288-L445 HydrophobicContact CG-CD2 3.83Å; V291-L445 HydrophobicContact CB-CD1 4.31Å; V291-L445 HydrophobicContact CB-CD2 4.02Å; V291-L445 HydrophobicContact CG1-CD1 4.27Å; V291-L445 HydrophobicContact CG1-CD2 3.9Å; V291-L445 HydrophobicContact CG2-CD1 4.32Å; L292-L445 HydrophobicContact CD2-CD2 3.83Å; L292-L445 HydrophobicContact CG-CD2 3.81Å; Y375-L445 HydrophobicContact CD2-CD1 4.24Å; Y375-L445 HydrophobicContact CE2-CD1 4.08Å; V441-L445 HydrophobicContact CG2-CD1 4.28Å; V441-L445 PolarHBondContact O-N 3.49Å; D442-L445 PolarHBondContact O-N 3.05Å; L445-R447 PolarHBondContact O-N 2.81Å; L445-R447 VanDerWaalsContact O-N 3.11Å; L445-F448 PolarHBondContact O-N 2.95Å; L445-R449 WeakPolarHBondContact O-CG 3.17Å; L445-R449 PolarHBondContact O-N 2.88Å
446	D	86	Confident	84.5	Confident	6 Å²	6	19.7 Å²	19.7	3%	0.032	10%	0.103	C	C	.	.	H	α-helix	trans	-52.2	-34.3	179	-167.6	65.3	0	0	0	112.9	S333 P414 N415 D442 L444 R449 T450	S333-D446 VanDerWaalsContact OG-C 3.3Å; S333-D446 PolarHBondContact OG-O 3.06Å; S333-D446 PolarHBondContact OG-OD2 3.43Å; P414-D446 WeakPolarHBondContact CA-OD2 3.36Å; N415-D446 PolarHBondContact N-OD1 2.92Å; N415-D446 PolarHBondContact N-OD2 3.26Å; D442-D446 WeakPolarHBondContact O-CB 3.3Å; D442-D446 PolarHBondContact O-N 3.25Å; L444-D446 PolarHBondContact O-N 3.4Å; D446-R449 PolarHBondContact O-N 3.04Å; D446-R449 IonicContact OD1-CZ 2.81Å; D446-R449 IonicContact OD1-NH1 3.91Å; D446-R449 PolarHBondContact OD1-NH1 3.03Å; D446-R449 IonicContact OD1-NH2 2.71Å; D446-R449 PolarHBondContact OD1-NH2 3.29Å; D446-T450 WeakPolarHBondContact O-CB 3.47Å; D446-T450 PolarHBondContact O-N 3.35Å; D446-T450 PolarHBondContact O-OG1 3.45Å
447	R	83.9	Confident	85.8	Confident	20 Å²	20	17.5 Å²	17.5	8%	0.075	9%	0.089	C	C	.	.	H	α-helix	trans	-66.7	-46.2	178.2	-59.5	176.1	173.2	-73.2	-6.9	111.8	L24 L330 M331 S333 W443 L444 L445 M451	L24-R447 VanDerWaalsContact CD1-NH2 3.29Å; L330-R447 HydrophobicContact CD1-CB 3.81Å; L330-R447 HydrophobicContact CG-CB 4.43Å; L330-R447 PolarHBondContact O-NH1 3.24Å; M331-R447 PolarHBondContact O-NH1 3.27Å; S333-R447 WeakPolarHBondContact OG-CA 3.34Å; S333-R447 PolarHBondContact OG-N 2.89Å; W443-R447 WeakPolarHBondContact O-CG 3.33Å; W443-R447 PolarHBondContact O-NE 3.05Å; L444-R447 WeakPolarHBondContact O-CB 3.42Å; L444-R447 PolarHBondContact O-N 3.4Å; L445-R447 PolarHBondContact O-N 2.81Å; L445-R447 VanDerWaalsContact O-N 3.11Å; R447-M451 WeakPolarHBondContact O-CB 3.23Å; R447-M451 PolarHBondContact O-N 3.49Å
448	F	93	Very high	87.1	Confident	66 Å²	66	15.4 Å²	15.4	29%	0.289	8%	0.078	S	C	.	.	H	α-helix	trans	-70.4	-38.5	176.7	-66.7	-78.9	0	0	0	110.6	L292 L295 L330 L444 L445 T450 M451 I452	L292-F448 HydrophobicContact CD2-CB 4.08Å; L292-F448 HydrophobicContact CD2-CD1 4.46Å; L292-F448 HydrophobicContact CD2-CD2 3.35Å; L292-F448 HydrophobicContact CD2-CE2 3.81Å; L292-F448 HydrophobicContact CD2-CG 3.72Å; L295-F448 HydrophobicContact CD1-CB 3.77Å; L330-F448 HydrophobicContact CD1-CD1 3.89Å; L330-F448 HydrophobicContact CD1-CE1 3.93Å; L330-F448 HydrophobicContact CD1-CG 4.24Å; L330-F448 HydrophobicContact CD1-CZ 4.33Å; L444-F448 HydrophobicContact CD1-CE2 3.85Å; L444-F448 HydrophobicContact CG-CE2 4.19Å; L444-F448 WeakPolarHBondContact O-CD2 3.45Å; L445-F448 PolarHBondContact O-N 2.95Å; F448-T450 PolarHBondContact O-N 3.33Å; F448-M451 HydrophobicContact CD1-CE 4.02Å; F448-M451 PolarHBondContact O-N 3.38Å; F448-I452 WeakPolarHBondContact O-CG1 3.26Å; F448-I452 PolarHBondContact O-N 3.38Å
449	R	94.4	Very high	88	Confident	2 Å²	2	15.4 Å²	15.4	1%	0.008	8%	0.078	C	C	.	.	H	α-helix	trans	-56	-51.7	173.6	-66.9	-172.6	-65.2	109.3	-8	110.7	L295 D442 L445 D446 M451 I452 N453	L295-R449 HydrophobicContact CD1-CG 3.95Å; L295-R449 HydrophobicContact CD2-CG 4.5Å; D442-R449 VanDerWaalsContact CG-NH2 3.28Å; D442-R449 IonicContact OD1-CZ 3.27Å; D442-R449 IonicContact OD1-NE 3.48Å; D442-R449 PolarHBondContact OD1-NE 3.12Å; D442-R449 IonicContact OD1-NH2 2.93Å; D442-R449 PolarHBondContact OD1-NH2 2.71Å; D442-R449 IonicContact OD2-NH2 2.8Å; D442-R449 PolarHBondContact OD2-NH2 3.14Å; L445-R449 WeakPolarHBondContact O-CG 3.17Å; L445-R449 PolarHBondContact O-N 2.88Å; D446-R449 PolarHBondContact O-N 3.04Å; D446-R449 IonicContact OD1-CZ 2.81Å; D446-R449 IonicContact OD1-NH1 3.91Å; D446-R449 PolarHBondContact OD1-NH1 3.03Å; D446-R449 IonicContact OD1-NH2 2.71Å; D446-R449 PolarHBondContact OD1-NH2 3.29Å; R449-M451 VanDerWaalsContact C-N 3.34Å; R449-M451 PolarHBondContact O-N 2.84Å; R449-I452 PolarHBondContact O-N 2.88Å; R449-I452 VanDerWaalsContact O-N 3.15Å; R449-N453 PolarHBondContact O-N 3.31Å; R449-N453 PolarHBondContact O-OD1 3.41Å
450	T	89.6	Confident	89.2	Confident	6 Å²	6	14.5 Å²	14.5	4%	0.037	7%	0.072	C	C	.	.	H	α-helix	trans	-57	-46.9	176.9	-56.6	0	0	0	0	111.7	A329 S333 S334 D446 F448 I452 N453 V454	A329-T450 HydrophobicContact CB-CG2 4.03Å; S333-T450 VanDerWaalsContact C-OG1 3.24Å; S333-T450 PolarHBondContact O-OG1 2.96Å; S334-T450 VanDerWaalsContact C-CG2 3.48Å; S334-T450 VanDerWaalsContact N-CG2 3.32Å; D446-T450 WeakPolarHBondContact O-CB 3.47Å; D446-T450 PolarHBondContact O-N 3.35Å; D446-T450 PolarHBondContact O-OG1 3.45Å; F448-T450 PolarHBondContact O-N 3.33Å; T450-I452 VanDerWaalsContact C-N 3.28Å; T450-I452 PolarHBondContact O-N 3.38Å; T450-N453 PolarHBondContact O-N 3.39Å; T450-V454 WeakPolarHBondContact O-CG2 3.41Å; T450-V454 PolarHBondContact O-N 3.37Å
451	M	93.4	Very high	90.4	Very high	44 Å²	44	13.4 Å²	13.4	22%	0.217	6%	0.064	C	C	.	.	H	α-helix	trans	-59	-40.3	178.9	-174.7	-179.5	71.3	0	0	111.9	L326 L330 R447 F448 R449 L455	L326-M451 HydrophobicContact CB-CG 3.94Å; L326-M451 HydrophobicContact CB-SD 4.37Å; L326-M451 HydrophobicContact CD2-CG 4.06Å; L326-M451 WeakPolarHBondContact CD2-O 3.25Å; L330-M451 HydrophobicContact CB-SD 4.47Å; L330-M451 HydrophobicContact CD1-SD 4.31Å; R447-M451 WeakPolarHBondContact O-CB 3.23Å; R447-M451 PolarHBondContact O-N 3.49Å; F448-M451 HydrophobicContact CD1-CE 4.02Å; F448-M451 PolarHBondContact O-N 3.38Å; R449-M451 VanDerWaalsContact C-N 3.34Å; R449-M451 PolarHBondContact O-N 2.84Å; M451-L455 WeakPolarHBondContact O-CB 3.29Å; M451-L455 PolarHBondContact O-N 2.88Å
452	I	96.4	Very high	91.3	Very high	4 Å²	4	12.3 Å²	12.3	2%	0.021	6%	0.058	C	C	.	.	H	α-helix	trans	-72.3	-40.1	178.7	-59.5	-28	0	0	0	111.4	L295 A299 L303 F448 R449 T450 V454 L455 G456	L295-I452 HydrophobicContact CB-CG1 4.06Å; L295-I452 HydrophobicContact CD2-CB 4.42Å; L295-I452 HydrophobicContact CD2-CG1 4.1Å; A299-I452 HydrophobicContact CB-CD1 3.36Å; A299-I452 HydrophobicContact CB-CG1 4.13Å; L303-I452 HydrophobicContact CD1-CG2 4.37Å; F448-I452 WeakPolarHBondContact O-CG1 3.26Å; F448-I452 PolarHBondContact O-N 3.38Å; R449-I452 PolarHBondContact O-N 2.88Å; R449-I452 VanDerWaalsContact O-N 3.15Å; T450-I452 VanDerWaalsContact C-N 3.28Å; T450-I452 PolarHBondContact O-N 3.38Å; I452-V454 PolarHBondContact O-N 3.32Å; I452-L455 WeakPolarHBondContact O-CB 3.48Å; I452-L455 PolarHBondContact O-N 2.87Å; I452-L455 VanDerWaalsContact O-N 3.14Å; I452-G456 PolarHBondContact O-N 3.4Å
453	N	95.3	Very high	92.1	Very high	4 Å²	4	12.5 Å²	12.5	2%	0.021	6%	0.059	C	C	.	.	H	α-helix	trans	-57.6	-49.2	175.8	-62.7	-9	0	0	0	110.6	M369 D370 G371 T372 R449 T450 L455 G456 D457	M369-N453 WeakPolarHBondContact CA-OD1 3.41Å; D370-N453 PolarHBondContact N-OD1 3.06Å; G371-N453 WeakPolarHBondContact CA-OD1 3.48Å; G371-N453 PolarHBondContact N-OD1 3.27Å; T372-N453 PolarHBondContact OG1-ND2 3.3Å; R449-N453 PolarHBondContact O-N 3.31Å; R449-N453 PolarHBondContact O-OD1 3.41Å; T450-N453 PolarHBondContact O-N 3.39Å; N453-L455 VanDerWaalsContact C-N 3.29Å; N453-L455 PolarHBondContact O-N 3.47Å; N453-G456 PolarHBondContact O-N 3.49Å; N453-G456 VanDerWaalsContact O-N 3.16Å; N453-D457 VanDerWaalsContact O-CG 3.29Å; N453-D457 PolarHBondContact O-N 3.23Å
454	V	94.2	Very high	93	Very high	3 Å²	3	10.3 Å²	10.3	2%	0.018	5%	0.05	C	C	.	.	H	α-helix	trans	-62.2	-36.2	176.8	173.9	0	0	0	0	112.2	L326 A329 T338 T342 T450 I452 A458	L326-V454 HydrophobicContact CD2-CG1 4.42Å; A329-V454 HydrophobicContact CB-CB 4.27Å; A329-V454 HydrophobicContact CB-CG2 3.9Å; T338-V454 WeakPolarHBondContact OG1-CG2 3.5Å; T342-V454 HydrophobicContact CG2-CG1 4.04Å; T342-V454 WeakPolarHBondContact OG1-CG1 3.3Å; T450-V454 WeakPolarHBondContact O-CG2 3.41Å; T450-V454 PolarHBondContact O-N 3.37Å; I452-V454 PolarHBondContact O-N 3.32Å; V454-A458 WeakPolarHBondContact O-CB 3.46Å; V454-A458 PolarHBondContact O-N 2.86Å; V454-A458 VanDerWaalsContact O-N 3.11Å
455	L	97.2	Very high	93.7	Very high	7 Å²	7	10.9 Å²	10.9	4%	0.037	5%	0.052	C	C	.	.	H	α-helix	trans	-67.2	-42.2	175.5	-176.5	57.8	0	0	0	111.9	A299 L303 T319 L326 M451 I452 N453 D457 A458 Y459	A299-L455 HydrophobicContact CB-CD2 4.01Å; L303-L455 HydrophobicContact CD1-CG 4.43Å; T319-L455 HydrophobicContact CG2-CD1 4.08Å; L326-L455 HydrophobicContact CD1-CD1 4.18Å; L326-L455 HydrophobicContact CD2-CB 3.76Å; L326-L455 HydrophobicContact CD2-CD1 4.22Å; L326-L455 HydrophobicContact CD2-CG 4.48Å; M451-L455 WeakPolarHBondContact O-CB 3.29Å; M451-L455 PolarHBondContact O-N 2.88Å; I452-L455 WeakPolarHBondContact O-CB 3.48Å; I452-L455 PolarHBondContact O-N 2.87Å; I452-L455 VanDerWaalsContact O-N 3.14Å; N453-L455 VanDerWaalsContact C-N 3.29Å; N453-L455 PolarHBondContact O-N 3.47Å; L455-D457 VanDerWaalsContact C-N 3.34Å; L455-D457 PolarHBondContact O-N 2.63Å; L455-A458 PolarHBondContact O-N 3.39Å; L455-Y459 HydrophobicContact CD1-CD2 3.79Å; L455-Y459 HydrophobicContact CD1-CE2 3.53Å; L455-Y459 HydrophobicContact CD2-CE2 4.13Å; L455-Y459 HydrophobicContact CG-CD2 3.79Å; L455-Y459 HydrophobicContact CG-CE2 3.7Å; L455-Y459 WeakPolarHBondContact O-CD2 3.34Å; L455-Y459 PolarHBondContact O-N 2.81Å
456	G	96.7	Very high	93.9	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-57.6	-45.9	175.8	0	0	0	0	0	111.7	Y100 I452 N453 Y459 G460	Y100-G456 WeakPolarHBondContact CE1-O 3.43Å; Y100-G456 PolarHBondContact OH-O 3.31Å; I452-G456 PolarHBondContact O-N 3.4Å; N453-G456 PolarHBondContact O-N 3.49Å; N453-G456 VanDerWaalsContact O-N 3.16Å; G456-Y459 PolarHBondContact O-N 3.21Å; G456-G460 PolarHBondContact O-N 3.29Å
457	D	94.4	Very high	94.2	Very high	4 Å²	4	19.5 Å²	19.5	2%	0.021	9%	0.093	C	C	.	.	H	α-helix	trans	-63.5	-43.9	177.6	-61.5	-15.1	0	0	0	112.1	L361 G364 A365 N368 N453 L455 G460 A461	L361-D457 HydrophobicContact CD2-CB 4.06Å; G364-D457 VanDerWaalsContact C-CG 3.48Å; G364-D457 WeakPolarHBondContact CA-OD1 3.43Å; A365-D457 WeakPolarHBondContact CA-OD2 3.33Å; A365-D457 PolarHBondContact N-OD2 3.26Å; A365-D457 VanDerWaalsContact N-OD2 3.16Å; N368-D457 VanDerWaalsContact CB-OD1 3.29Å; N368-D457 WeakPolarHBondContact CB-OD1 3.48Å; N368-D457 PolarHBondContact ND2-OD1 2.78Å; N453-D457 VanDerWaalsContact O-CG 3.29Å; N453-D457 PolarHBondContact O-N 3.23Å; L455-D457 VanDerWaalsContact C-N 3.34Å; L455-D457 PolarHBondContact O-N 2.63Å; D457-G460 PolarHBondContact O-N 3.07Å; D457-A461 PolarHBondContact O-N 3.42Å
458	A	95.8	Very high	94.5	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-62.7	-45.4	178.5	0	0	0	0	0	111.3	F318 M322 V454 L455 G460 A461 G462	F318-A458 HydrophobicContact CE1-CB 4.1Å; F318-A458 HydrophobicContact CZ-CB 4.5Å; F318-A458 WeakPolarHBondContact CZ-O 3.27Å; M322-A458 HydrophobicContact CE-CB 3.7Å; M322-A458 HydrophobicContact CG-CB 3.94Å; M322-A458 HydrophobicContact SD-CB 4.14Å; V454-A458 WeakPolarHBondContact O-CB 3.46Å; V454-A458 PolarHBondContact O-N 2.86Å; V454-A458 VanDerWaalsContact O-N 3.11Å; L455-A458 PolarHBondContact O-N 3.39Å; A458-G460 VanDerWaalsContact C-N 3.31Å; A458-G460 PolarHBondContact O-N 3.25Å; A458-A461 PolarHBondContact O-N 2.89Å; A458-G462 PolarHBondContact O-N 2.95Å
459	Y	97.4	Very high	94.3	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62.9	-39	173.8	-83.6	-53.8	0	0	0	112.3	Y100 L303 P304 F307 P315 F318 T319 L455 G456 A461 G462 I463	Y100-Y459 WeakPolarHBondContact OH-CB 3.42Å; L303-Y459 HydrophobicContact CB-CD2 3.78Å; L303-Y459 HydrophobicContact CB-CE2 3.99Å; L303-Y459 HydrophobicContact CD1-CD2 4.41Å; P304-Y459 HydrophobicContact CG-CE2 4.3Å; F307-Y459 HydrophobicContact CB-CD1 3.71Å; F307-Y459 HydrophobicContact CB-CE1 3.84Å; F307-Y459 HydrophobicContact CB-CG 4.49Å; F307-Y459 HydrophobicContact CD1-CD1 4.38Å; F307-Y459 HydrophobicContact CD1-CE1 4.13Å; F307-Y459 AromaticContact CD2-CD1 3.31Å; F307-Y459 HydrophobicContact CD2-CD1 3.31Å; F307-Y459 AromaticContact CD2-CE1 3.9Å; F307-Y459 HydrophobicContact CD2-CE1 3.9Å; F307-Y459 HydrophobicContact CD2-CG 4.33Å; F307-Y459 AromaticContact CE2-CD1 3.92Å; F307-Y459 HydrophobicContact CE2-CD1 3.92Å; F307-Y459 HydrophobicContact CE2-CE1 4.43Å; F307-Y459 AromaticContact CG-CD1 3.55Å; F307-Y459 HydrophobicContact CG-CD1 3.55Å; F307-Y459 AromaticContact CG-CE1 3.69Å; F307-Y459 HydrophobicContact CG-CE1 3.69Å; P315-Y459 HydrophobicContact CB-CE1 3.95Å; P315-Y459 WeakPolarHBondContact CB-OH 3.15Å; P315-Y459 PolarHBondContact O-OH 2.79Å; F318-Y459 AromaticContact CD1-CD1 3.71Å; F318-Y459 HydrophobicContact CD1-CD1 3.71Å; F318-Y459 AromaticContact CD1-CE1 3.65Å; F318-Y459 HydrophobicContact CD1-CE1 3.65Å; F318-Y459 AromaticContact CE1-CD1 3.9Å; F318-Y459 HydrophobicContact CE1-CD1 3.9Å; F318-Y459 HydrophobicContact CE1-CE1 4.3Å; F318-Y459 HydrophobicContact CE1-CG 4.45Å; F318-Y459 HydrophobicContact CG-CE1 4.39Å; T319-Y459 PolarHBondContact OG1-OH 3.28Å; L455-Y459 HydrophobicContact CD1-CD2 3.79Å; L455-Y459 HydrophobicContact CD1-CE2 3.53Å; L455-Y459 HydrophobicContact CD2-CE2 4.13Å; L455-Y459 HydrophobicContact CG-CD2 3.79Å; L455-Y459 HydrophobicContact CG-CE2 3.7Å; L455-Y459 WeakPolarHBondContact O-CD2 3.34Å; L455-Y459 PolarHBondContact O-N 2.81Å; G456-Y459 PolarHBondContact O-N 3.21Å; Y459-A461 PolarHBondContact O-N 2.95Å; Y459-G462 PolarHBondContact O-N 3.28Å; Y459-I463 WeakPolarHBondContact O-CG1 3.48Å; Y459-I463 PolarHBondContact O-N 3.29Å
460	G	95.8	Very high	93.9	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-56.2	-48	173.4	0	0	0	0	0	111.9	Y100 G456 D457 A458 G462 I463 V464	Y100-G460 PolarHBondContact OH-N 3.38Å; G456-G460 PolarHBondContact O-N 3.29Å; D457-G460 PolarHBondContact O-N 3.07Å; A458-G460 VanDerWaalsContact C-N 3.31Å; A458-G460 PolarHBondContact O-N 3.25Å; G460-G462 VanDerWaalsContact C-N 3.33Å; G460-G462 PolarHBondContact O-N 2.68Å; G460-I463 PolarHBondContact O-N 3.33Å; G460-V464 WeakPolarHBondContact O-CB 3.34Å; G460-V464 WeakPolarHBondContact O-CG2 3.47Å; G460-V464 PolarHBondContact O-N 3.31Å
461	A	93.5	Very high	93.5	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-59.2	-42.5	177.2	0	0	0	0	0	112.2	I352 V360 L361 D457 A458 Y459 Q465	I352-A461 HydrophobicContact CD1-CB 3.89Å; I352-A461 HydrophobicContact CG2-CB 4.36Å; V360-A461 HydrophobicContact CB-CB 4.33Å; V360-A461 HydrophobicContact CG1-CB 4.07Å; L361-A461 HydrophobicContact CD2-CB 4.02Å; L361-A461 HydrophobicContact CG-CB 4.46Å; D457-A461 PolarHBondContact O-N 3.42Å; A458-A461 PolarHBondContact O-N 2.89Å; Y459-A461 PolarHBondContact O-N 2.95Å; A461-Q465 VanDerWaalsContact O-CB 3.31Å; A461-Q465 WeakPolarHBondContact O-CB 3.43Å; A461-Q465 PolarHBondContact O-N 3.06Å
462	G	95.7	Very high	92.9	Very high	4 Å²	4	30.6 Å²	30.6	4%	0.041	14%	0.135	C	C	.	.	H	α-helix	trans	-68.6	-37.8	177.7	0	0	0	0	0	113.8	A458 Y459 G460 K466	A458-G462 PolarHBondContact O-N 2.95Å; Y459-G462 PolarHBondContact O-N 3.28Å; G460-G462 VanDerWaalsContact C-N 3.33Å; G460-G462 PolarHBondContact O-N 2.68Å; G462-K466 PolarHBondContact O-N 2.8Å
463	I	96.6	Very high	92.3	Very high	3 Å²	3	34.6 Å²	34.6	2%	0.015	15%	0.154	C	C	.	.	H	α-helix	trans	-67.1	-49.6	175.7	-73.9	162.2	0	0	0	110.5	Y100 I306 F307 I310 V311 Y459 G460 Q465 K466 L467	Y100-I463 HydrophobicContact CD2-CD1 3.81Å; Y100-I463 HydrophobicContact CE2-CD1 3.33Å; I306-I463 HydrophobicContact CG2-CD1 4.02Å; F307-I463 HydrophobicContact CB-CD1 4.41Å; F307-I463 HydrophobicContact CD2-CD1 4.27Å; F307-I463 HydrophobicContact CD2-CG1 3.83Å; I310-I463 HydrophobicContact CD1-CD1 4.45Å; I310-I463 HydrophobicContact CD1-CG2 3.95Å; I310-I463 HydrophobicContact CG2-CG2 4.01Å; V311-I463 HydrophobicContact CG2-CB 4.48Å; V311-I463 HydrophobicContact CG2-CG1 3.86Å; Y459-I463 WeakPolarHBondContact O-CG1 3.48Å; Y459-I463 PolarHBondContact O-N 3.29Å; G460-I463 PolarHBondContact O-N 3.33Å; I463-Q465 VanDerWaalsContact C-N 3.28Å; I463-Q465 PolarHBondContact O-N 2.69Å; I463-K466 PolarHBondContact O-N 2.86Å; I463-K466 VanDerWaalsContact O-N 3.1Å; I463-L467 HydrophobicContact CG2-CD1 3.85Å; I463-L467 HydrophobicContact CG2-CG 4.41Å; I463-L467 WeakPolarHBondContact O-CG 3.47Å; I463-L467 PolarHBondContact O-N 2.92Å
464	V	93.9	Very high	91.5	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-62.7	-36.8	180	175.3	0	0	0	0	110.8	I93 R96 A97 I356 V360 G460 K466 L467 S468	I93-V464 HydrophobicContact CG2-CG1 3.64Å; R96-V464 HydrophobicContact CB-CG2 4.4Å; A97-V464 HydrophobicContact CB-CG2 4Å; I356-V464 HydrophobicContact CD1-CG1 4.36Å; I356-V464 HydrophobicContact CG2-CB 4.29Å; I356-V464 HydrophobicContact CG2-CG1 4.14Å; V360-V464 HydrophobicContact CG2-CB 4.26Å; V360-V464 HydrophobicContact CG2-CG1 4.06Å; V360-V464 HydrophobicContact CG2-CG2 4.43Å; G460-V464 WeakPolarHBondContact O-CB 3.34Å; G460-V464 WeakPolarHBondContact O-CG2 3.47Å; G460-V464 PolarHBondContact O-N 3.31Å; V464-K466 PolarHBondContact O-N 3.4Å; V464-L467 PolarHBondContact O-N 3.42Å; V464-S468 WeakPolarHBondContact O-CB 3.27Å; V464-S468 PolarHBondContact O-N 3.46Å; V464-S468 PolarHBondContact O-OG 2.97Å
465	Q	93.7	Very high	90.4	Very high	56 Å²	56	45.3 Å²	45.3	26%	0.262	20%	0.197	S	C	.	.	H	α-helix	trans	-59.5	-46.1	172.6	-179.8	-176.1	6.2	0	0	111.8	R351 I352 I356 A461 I463 S468 K469 L472	R351-Q465 PolarHBondContact O-NE2 3.33Å; I352-Q465 HydrophobicContact CG2-CB 4.35Å; I356-Q465 HydrophobicContact CG1-CB 4.41Å; I356-Q465 HydrophobicContact CG2-CB 4.47Å; A461-Q465 VanDerWaalsContact O-CB 3.31Å; A461-Q465 WeakPolarHBondContact O-CB 3.43Å; A461-Q465 PolarHBondContact O-N 3.06Å; I463-Q465 VanDerWaalsContact C-N 3.28Å; I463-Q465 PolarHBondContact O-N 2.69Å; Q465-S468 PolarHBondContact O-N 3.16Å; Q465-K469 PolarHBondContact O-N 2.77Å; Q465-L472 HydrophobicContact CG-CD1 4.37Å
466	K	94.6	Very high	89.3	Confident	110 Å²	110	48.1 Å²	48.1	48%	0.478	21%	0.211	S	C	.	.	H	α-helix	trans	-63.4	-43.9	178.8	176	63.8	177.4	-178.7	0	111.7	V311 G462 I463 V464 S468	V311-K466 HydrophobicContact CG1-CB 4.44Å; V311-K466 HydrophobicContact CG2-CB 4.1Å; G462-K466 PolarHBondContact O-N 2.8Å; I463-K466 PolarHBondContact O-N 2.86Å; I463-K466 VanDerWaalsContact O-N 3.1Å; V464-K466 PolarHBondContact O-N 3.4Å; K466-S468 VanDerWaalsContact C-N 3.3Å
467	L	93.2	Very high	88.3	Confident	77 Å²	77	53.7 Å²	53.7	40%	0.403	24%	0.241	S	C	.	.	H	α-helix	trans	-69.6	-30.8	-179.4	-66.6	175.1	0	0	0	112	R96 I310 I463 V464	R96-L467 PolarHBondContact NH1-O 2.83Å; I310-L467 HydrophobicContact CG2-CD1 4.42Å; I310-L467 HydrophobicContact CG2-CD2 3.91Å; I310-L467 HydrophobicContact CG2-CG 4.12Å; I463-L467 HydrophobicContact CG2-CD1 3.85Å; I463-L467 HydrophobicContact CG2-CG 4.41Å; I463-L467 WeakPolarHBondContact O-CG 3.47Å; I463-L467 PolarHBondContact O-N 2.92Å; V464-L467 PolarHBondContact O-N 3.42Å
468	S	89.8	Confident	87	Confident	0 Å²	0	57.9 Å²	57.9	0%	0	26%	0.262	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96.9	18.6	-175.5	-49.6	0	0	0	0	115.2	R96 V464 Q465 K466 R470 E471 L472	R96-S468 PolarHBondContact NH1-OG 3.49Å; V464-S468 WeakPolarHBondContact O-CB 3.27Å; V464-S468 PolarHBondContact O-N 3.46Å; V464-S468 PolarHBondContact O-OG 2.97Å; Q465-S468 PolarHBondContact O-N 3.16Å; K466-S468 VanDerWaalsContact C-N 3.3Å; S468-R470 VanDerWaalsContact C-N 3.33Å; S468-R470 PolarHBondContact O-N 2.71Å; S468-E471 VanDerWaalsContact C-OE2 3.25Å; S468-E471 WeakPolarHBondContact CA-OE2 3.29Å; S468-E471 PolarHBondContact O-N 2.89Å; S468-L472 WeakPolarHBondContact O-CG 3.25Å; S468-L472 PolarHBondContact O-N 2.71Å
469	K	88.8	Confident	85.2	Confident	119 Å²	119	60.5 Å²	60.5	52%	0.517	28%	0.281	S	S	.	.	H	α-helix	trans	-58.6	-42	-176.8	-168.5	-178.4	-176.6	-145	0	112.9	Q465 E471 L472 E473	Q465-K469 PolarHBondContact O-N 2.77Å; K469-E471 VanDerWaalsContact C-N 3.35Å; K469-L472 PolarHBondContact O-N 2.91Å; K469-E473 WeakPolarHBondContact CE-OE1 3.08Å; K469-E473 IonicContact NZ-OE1 3.35Å; K469-E473 PolarHBondContact NZ-OE1 2.92Å; K469-E473 VanDerWaalsContact O-CG 3.3Å; K469-E473 WeakPolarHBondContact O-CG 3.48Å; K469-E473 PolarHBondContact O-N 2.77Å
470	R	85.1	Confident	83.3	Confident	205 Å²	205	65.6 Å²	65.6	77%	0.774	31%	0.308	S	S	*	.	H	α-helix	trans	-68	-36.6	-179	-70.2	-178.8	176	169.3	-1.6	112.1	S468 R474	S468-R470 VanDerWaalsContact C-N 3.33Å; S468-R470 PolarHBondContact O-N 2.71Å; R470-R474 WeakPolarHBondContact O-CB 3.35Å; R470-R474 PolarHBondContact O-N 3.18Å
471	E	81.9	Confident	81.4	Confident	34 Å²	34	70.1 Å²	70.1	16%	0.159	34%	0.335	C	S	.	.	H	α-helix	trans	-69.2	-42.4	177.2	-64.9	84.5	169.4	0	0	110.8	R96 S468 K469 R474 M475	R96-E471 IonicContact CZ-OE1 3.23Å; R96-E471 IonicContact NH1-OE1 2.88Å; R96-E471 PolarHBondContact NH1-OE1 3.09Å; R96-E471 IonicContact NH1-OE2 3.05Å; R96-E471 PolarHBondContact NH1-OE2 3.2Å; R96-E471 VanDerWaalsContact NH1-OE2 3.12Å; R96-E471 IonicContact NH2-OE1 2.75Å; R96-E471 PolarHBondContact NH2-OE1 3.39Å; R96-E471 IonicContact NH2-OE2 2.74Å; S468-E471 VanDerWaalsContact C-OE2 3.25Å; S468-E471 WeakPolarHBondContact CA-OE2 3.29Å; S468-E471 PolarHBondContact O-N 2.89Å; K469-E471 VanDerWaalsContact C-N 3.35Å; E471-R474 PolarHBondContact O-N 3.02Å; E471-M475 VanDerWaalsContact O-CG 3.31Å; E471-M475 WeakPolarHBondContact O-CG 3.32Å; E471-M475 PolarHBondContact O-N 2.79Å
472	L	81.1	Confident	79.4	Confident	13 Å²	13	75.5 Å²	75.5	7%	0.068	36%	0.364	C	S	.	.	H	α-helix	trans	-61.6	-46.5	174.3	-67.5	170.7	0	0	0	111.7	D353 R355 I356 Q465 S468 K469 R474 M475 D476	D353-L472 HydrophobicContact CB-CD1 4.18Å; D353-L472 HydrophobicContact CB-CD2 4.42Å; R355-L472 HydrophobicContact CB-CD2 4.3Å; I356-L472 HydrophobicContact CD1-CD1 4.28Å; I356-L472 HydrophobicContact CD1-CD2 4.07Å; I356-L472 HydrophobicContact CD1-CG 4.43Å; I356-L472 HydrophobicContact CG1-CD1 4.03Å; I356-L472 HydrophobicContact CG1-CD2 4.14Å; Q465-L472 HydrophobicContact CG-CD1 4.37Å; S468-L472 WeakPolarHBondContact O-CG 3.25Å; S468-L472 PolarHBondContact O-N 2.71Å; K469-L472 PolarHBondContact O-N 2.91Å; L472-R474 VanDerWaalsContact C-N 3.28Å; L472-R474 PolarHBondContact O-N 2.88Å; L472-M475 PolarHBondContact O-N 3.5Å; L472-M475 VanDerWaalsContact O-N 3.14Å; L472-D476 PolarHBondContact O-N 2.85Å
473	E	83.6	Confident	77.4	Confident	88 Å²	88	80.9 Å²	80.9	41%	0.411	40%	0.396	S	S	.	.	H	α-helix	trans	-59.4	-38.3	176	-74.1	167.8	-177.2	0	0	111.8	K469 D476 L477	K469-E473 WeakPolarHBondContact CE-OE1 3.08Å; K469-E473 IonicContact NZ-OE1 3.35Å; K469-E473 PolarHBondContact NZ-OE1 2.92Å; K469-E473 VanDerWaalsContact O-CG 3.3Å; K469-E473 WeakPolarHBondContact O-CG 3.48Å; K469-E473 PolarHBondContact O-N 2.77Å; E473-D476 PolarHBondContact O-N 3.48Å; E473-L477 WeakPolarHBondContact O-CG 3.32Å; E473-L477 PolarHBondContact O-N 3.32Å; E473-L477 VanDerWaalsContact O-N 3.15Å
474	R	78	Confident	75.4	Confident	174 Å²	174	84.6 Å²	84.6	66%	0.657	43%	0.427	S	S	*	.	H	α-helix	trans	-66.9	-40.6	175.5	-175.4	-174.2	-67.1	-163.4	-6	112.2	R470 E471 L472 D476 L477 I478	R470-R474 WeakPolarHBondContact O-CB 3.35Å; R470-R474 PolarHBondContact O-N 3.18Å; E471-R474 PolarHBondContact O-N 3.02Å; L472-R474 VanDerWaalsContact C-N 3.28Å; L472-R474 PolarHBondContact O-N 2.88Å; R474-D476 VanDerWaalsContact C-N 3.3Å; R474-L477 PolarHBondContact O-N 3.49Å; R474-I478 HydrophobicContact CG-CD1 4.05Å; R474-I478 WeakPolarHBondContact O-CG1 3.4Å; R474-I478 PolarHBondContact O-N 2.84Å; R474-I478 VanDerWaalsContact O-N 3.09Å
475	M	71.8	Confident	73.1	Confident	58 Å²	58	88.9 Å²	88.9	29%	0.286	45%	0.45	S	S	.	.	H	α-helix	trans	-63.9	-38.5	177.8	-69	172	93.9	0	0	111.3	V89 E471 L472 I478 S479	V89-M475 HydrophobicContact CG1-CE 3.85Å; V89-M475 HydrophobicContact CG1-CG 3.84Å; V89-M475 HydrophobicContact CG1-SD 3.6Å; E471-M475 VanDerWaalsContact O-CG 3.31Å; E471-M475 WeakPolarHBondContact O-CG 3.32Å; E471-M475 PolarHBondContact O-N 2.79Å; L472-M475 PolarHBondContact O-N 3.5Å; L472-M475 VanDerWaalsContact O-N 3.14Å; M475-I478 PolarHBondContact O-N 3.27Å; M475-S479 PolarHBondContact O-N 3.02Å; M475-S479 VanDerWaalsContact O-N 3.07Å; M475-S479 PolarHBondContact O-OG 3.1Å
476	D	74.1	Confident	70.7	Confident	65 Å²	65	91.1 Å²	91.1	35%	0.348	47%	0.469	S	S	.	.	H	α-helix	trans	-63.5	-43.8	175.9	-63.6	-22.2	0	0	0	111.3	R355 L472 E473 R474 I478 S479 D480	R355-D476 IonicContact CZ-OD1 3.46Å; R355-D476 IonicContact NH1-OD1 3.92Å; R355-D476 PolarHBondContact NH1-OD1 2.91Å; R355-D476 IonicContact NH2-OD1 3.87Å; R355-D476 PolarHBondContact NH2-OD1 3.37Å; R355-D476 IonicContact NH2-OD2 2.76Å; L472-D476 PolarHBondContact O-N 2.85Å; E473-D476 PolarHBondContact O-N 3.48Å; R474-D476 VanDerWaalsContact C-N 3.3Å; D476-I478 PolarHBondContact O-N 2.85Å; D476-S479 WeakPolarHBondContact CA-OG 3.47Å; D476-S479 PolarHBondContact O-N 3.44Å; D476-S479 PolarHBondContact O-OG 3.23Å; D476-D480 PolarHBondContact O-N 3Å
477	L	74.6	Confident	68.5	Low	117 Å²	117	94 Å²	94	61%	0.613	48%	0.482	S	S	*	.	H	α-helix	trans	-62.6	-39.6	177.1	-71.7	168.8	0	0	0	113	E473 R474 V481	E473-L477 WeakPolarHBondContact O-CG 3.32Å; E473-L477 PolarHBondContact O-N 3.32Å; E473-L477 VanDerWaalsContact O-N 3.15Å; R474-L477 PolarHBondContact O-N 3.49Å; L477-V481 WeakPolarHBondContact O-CG2 3.36Å; L477-V481 PolarHBondContact O-N 3.29Å; L477-V481 VanDerWaalsContact O-N 3.11Å
478	I	68.1	Low	66	Low	93 Å²	93	93.4 Å²	93.4	48%	0.477	49%	0.488	S	S	.	.	H	α-helix	trans	-67.9	-43.2	177.7	-65.5	164.4	0	0	0	110.2	R474 M475 D476 D480 V481 D482	R474-I478 HydrophobicContact CG-CD1 4.05Å; R474-I478 WeakPolarHBondContact O-CG1 3.4Å; R474-I478 PolarHBondContact O-N 2.84Å; R474-I478 VanDerWaalsContact O-N 3.09Å; M475-I478 PolarHBondContact O-N 3.27Å; D476-I478 PolarHBondContact O-N 2.85Å; I478-D480 VanDerWaalsContact C-N 3.33Å; I478-D480 PolarHBondContact O-N 2.75Å; I478-V481 PolarHBondContact O-N 2.91Å; I478-D482 PolarHBondContact O-N 3.36Å
479	S	58.4	Low	63.7	Low	55 Å²	55	101.7 Å²	101.7	39%	0.385	53%	0.531	S	S	.	.	H	α-helix	trans	-63.8	-37.2	177.2	53.4	0	0	0	0	113	M475 D476 V481 D482 V483	M475-S479 PolarHBondContact O-N 3.02Å; M475-S479 VanDerWaalsContact O-N 3.07Å; M475-S479 PolarHBondContact O-OG 3.1Å; D476-S479 WeakPolarHBondContact CA-OG 3.47Å; D476-S479 PolarHBondContact O-N 3.44Å; D476-S479 PolarHBondContact O-OG 3.23Å; S479-V481 VanDerWaalsContact C-N 3.34Å; S479-D482 PolarHBondContact O-N 2.92Å; S479-V483 VanDerWaalsContact O-CG2 3.24Å; S479-V483 WeakPolarHBondContact O-CG2 3.31Å; S479-V483 PolarHBondContact O-N 3.01Å; S479-V483 VanDerWaalsContact O-N 3.09Å
480	D	57.7	Low	61.4	Low	106 Å²	106	103.8 Å²	103.8	57%	0.567	54%	0.543	S	S	*	.	H	α-helix	trans	-70.8	-32	177.9	-75.4	-16.7	0	0	0	111.9	D476 I478 A484	D476-D480 PolarHBondContact O-N 3Å; I478-D480 VanDerWaalsContact C-N 3.33Å; I478-D480 PolarHBondContact O-N 2.75Å; D480-A484 WeakPolarHBondContact O-CB 3.48Å; D480-A484 PolarHBondContact O-N 2.82Å
481	V	56	Low	58.7	Low	95 Å²	95	100.3 Å²	100.3	58%	0.576	55%	0.545	S	S	*	.	H	α-helix	trans	-70.4	-41.9	174.7	171.9	0	0	0	0	111.5	L477 I478 S479 V483 A484 N485	L477-V481 WeakPolarHBondContact O-CG2 3.36Å; L477-V481 PolarHBondContact O-N 3.29Å; L477-V481 VanDerWaalsContact O-N 3.11Å; I478-V481 PolarHBondContact O-N 2.91Å; S479-V481 VanDerWaalsContact C-N 3.34Å; V481-V483 VanDerWaalsContact C-N 3.29Å; V481-V483 PolarHBondContact O-N 3.17Å; V481-A484 PolarHBondContact O-N 2.98Å; V481-N485 PolarHBondContact O-N 3.03Å
482	D	51.3	Low	56.1	Low	113 Å²	113	104.8 Å²	104.8	60%	0.604	58%	0.575	S	S	*	*	H	α-helix	trans	-65.3	-31.6	175.5	-79.3	-23.4	0	0	0	112.4	I478 S479	I478-D482 PolarHBondContact O-N 3.36Å; S479-D482 PolarHBondContact O-N 2.92Å
483	V	54	Low	53.7	Low	118 Å²	118	111.2 Å²	111.2	72%	0.715	61%	0.608	S	S	*	*	H	α-helix	trans	-80	-38.3	175.7	173.8	0	0	0	0	112	S479 V481	S479-V483 VanDerWaalsContact O-CG2 3.24Å; S479-V483 WeakPolarHBondContact O-CG2 3.31Å; S479-V483 PolarHBondContact O-N 3.01Å; S479-V483 VanDerWaalsContact O-N 3.09Å; V481-V483 VanDerWaalsContact C-N 3.29Å; V481-V483 PolarHBondContact O-N 3.17Å
484	A	52.9	Low	51.2	Low	80 Å²	80	113.4 Å²	113.4	66%	0.661	62%	0.623	S	S	*	*	H	α-helix	trans	-77.4	-20.4	-178.5	0	0	0	0	0	113.3	D480 V481	D480-A484 WeakPolarHBondContact O-CB 3.48Å; D480-A484 PolarHBondContact O-N 2.82Å; V481-A484 PolarHBondContact O-N 2.98Å
485	N	45.6	Very low	49	Very low	90 Å²	90	112.4 Å²	112.4	48%	0.481	63%	0.631	S	S	.	*			trans	-143.8	78.7	-176.8	-133.2	-18.8	0	0	0	112.9	V481 F487 A488	V481-N485 PolarHBondContact O-N 3.03Å; N485-F487 PolarHBondContact O-N 2.97Å; N485-A488 HydrophobicContact CB-CB 3.82Å; N485-A488 WeakPolarHBondContact ND2-CB 3.41Å
486	P	45.1	Very low	47.1	Very low	103 Å²	103	118.4 Å²	118.4	67%	0.669	66%	0.658	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.1	-4.3	179.1	-16.1	29	0	0	0	114.5
487	F	47	Very low	45.2	Very low	171 Å²	171	124 Å²	124	75%	0.75	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-135.1	5	-171	-84	-82.7	0	0	0	115.3	N485 L489	N485-F487 PolarHBondContact O-N 2.97Å; F487-L489 PolarHBondContact O-N 3.06Å; F487-L489 VanDerWaalsContact O-N 3.13Å
488	A	41.1	Very low	42.8	Very low	65 Å²	65	124.2 Å²	124.2	54%	0.537	69%	0.692	S	S	.	*			trans	-87.4	30.8	-174.4	0	0	0	0	0	115.9	N485	N485-A488 HydrophobicContact CB-CB 3.82Å; N485-A488 WeakPolarHBondContact ND2-CB 3.41Å
489	L	41	Very low	41	Very low	173 Å²	173	128.4 Å²	128.4	91%	0.906	71%	0.71	S	S	*	*			trans	-129.5	45.5	169.6	-105.3	153.3	0	0	0	111	F487	F487-L489 PolarHBondContact O-N 3.06Å; F487-L489 VanDerWaalsContact O-N 3.13Å
490	E	40.6	Very low	39.5	Very low	163 Å²	163	135.4 Å²	135.4	76%	0.762	73%	0.733	S	S	*	*			trans	-127.3	91.3	158	-86.6	-175.1	165.8	0	0	108.6
491	T	29.3	Very low	38.1	Very low	132 Å²	132	139.1 Å²	139.1	81%	0.81	74%	0.744	S	S	*	*			trans	171.3	96.2	139.9	26.9	0	0	0	0	109.1
492	T	27.8	Very low	36.7	Very low	128 Å²	128	139.5 Å²	139.5	79%	0.785	75%	0.751	S	S	*	*	S	Bend		166	118.7	102.1	44.7	0	0	0	0	111.1
493	L	30.1	Very low	35.6	Very low	149 Å²	149	143.9 Å²	143.9	78%	0.78	76%	0.761	S	S	*	*			trans	94.2	93.6	148.9	-58.1	163.9	0	0	0	119.2
494	D	29.9	Very low	34.5	Very low	134 Å²	134	144.2 Å²	144.2	72%	0.717	76%	0.763	S	S	*	*				74.3	107.1	126.7	-55	-12.2	0	0	0	121.5
495	D	32.3	Very low	33.5	Very low	153 Å²	153	148 Å²	148	82%	0.818	77%	0.772	S	S	*	*			trans	79.7	124.2	135	-69.4	-20.9	0	0	0	123
496	E	32	Very low	32.8	Very low	183 Å²	183	148 Å²	148	86%	0.855	79%	0.793	S	S	*	*			trans	92.8	103	158	-64.2	-172.8	177.7	0	0	120.8
497	E	34.2	Very low	31.9	Very low	184 Å²	184	146 Å²	146	86%	0.86	79%	0.792	S	S	*	*			trans	43.9	105.6	145.1	-68.5	-172.1	155.2	0	0	120.3
498	C	25.4	Very low	31.3	Very low	121 Å²	121	147.7 Å²	147.7	82%	0.818	80%	0.799	S	S	*	*				-171.8	119.1	119.9	-117.5	0	0	0	0	111.9	K500	C498-K500 PolarHBondContact O-N 3.02Å; C498-K500 VanDerWaalsContact O-N 3.09Å
499	E	30.1	Very low	30.6	Very low	181 Å²	181	150.5 Å²	150.5	85%	0.846	81%	0.809	S	S	*	*			trans	-56.2	109.5	164.9	-73.3	-173.2	143.1	0	0	110.8
500	K	27.3	Very low	30.3	Very low	201 Å²	201	147.7 Å²	147.7	87%	0.874	80%	0.799	S	S	*	*			trans	-103.8	102.1	162.1	-85.2	-176.7	178.2	175.4	0	109.4	C498 S502	C498-K500 PolarHBondContact O-N 3.02Å; C498-K500 VanDerWaalsContact O-N 3.09Å; K500-S502 PolarHBondContact O-N 3.49Å
501	K	27.5	Very low	29.7	Very low	184 Å²	184	147.1 Å²	147.1	80%	0.8	80%	0.802	S	S	*	*			trans	-67.2	112.3	164.5	-74.7	179.1	178.9	172.9	0	108.9
502	S	27.2	Very low	30	Very low	104 Å²	104	149.7 Å²	149.7	73%	0.727	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-66.4	127.6	173.1	66.2	0	0	0	0	110.6	K500	K500-S502 PolarHBondContact O-N 3.49Å
503	Y	28.3	Very low	30.3	Very low	204 Å²	204	149.2 Å²	149.2	80%	0.8	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-75.6	120.2	171.8	-100.9	-98.7	0	0	0	110
504	V	29.6	Very low	30.3	Very low	126 Å²	126	149.8 Å²	149.8	76%	0.764	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-101.9	136.5	168.6	176.2	0	0	0	0	109.3
505	N	32.8	Very low	30.4	Very low	159 Å²	159	147.3 Å²	147.3	85%	0.85	80%	0.8	S	S	*	*			trans	-21.2	134.2	175.9	-95.9	-37.4	0	0	0	117.2	G507	N505-G507 PolarHBondContact O-N 3.06Å; N505-G507 VanDerWaalsContact O-N 3.11Å
506	G	31.4	Very low	30.4	Very low	90 Å²	90	147.5 Å²	147.5	93%	0.928	80%	0.8	S	S	*	*			trans	-55.6	112.9	165.1	0	0	0	0	0	112
507	G	26.2	Very low	30.2	Very low	62 Å²	62	144.3 Å²	144.3	64%	0.639	80%	0.798	S	S	*	*			trans	-135.3	119.1	162.3	0	0	0	0	0	107.5	N505 T509	N505-G507 PolarHBondContact O-N 3.06Å; N505-G507 VanDerWaalsContact O-N 3.11Å; G507-T509 PolarHBondContact O-N 3.2Å
508	F	32.6	Very low	30.1	Very low	206 Å²	206	144.4 Å²	144.4	90%	0.904	80%	0.796	S	S	*	*			trans	-58.6	114.9	173.5	-113.7	-98.4	0	0	0	109.8	V510	F508-V510 HydrophobicContact CD1-CG2 4.44Å
509	T	28.1	Very low	30.3	Very low	123 Å²	123	145.3 Å²	145.3	76%	0.755	80%	0.797	S	S	*	*			trans	-132.4	110.4	155.9	50.9	0	0	0	0	108.2	G507 D511	G507-T509 PolarHBondContact O-N 3.2Å; T509-D511 PolarHBondContact O-N 3.05Å
510	V	34.4	Very low	30.5	Very low	115 Å²	115	144.4 Å²	144.4	70%	0.697	79%	0.793	S	S	*	*			trans	-73.8	107.7	168.9	173.1	0	0	0	0	106.6	F508	F508-V510 HydrophobicContact CD1-CG2 4.44Å
511	D	27.2	Very low	30.7	Very low	151 Å²	151	141.2 Å²	141.2	81%	0.807	79%	0.791	S	S	*	*			trans	-100.5	116.9	163.5	-100.9	-25.4	0	0	0	110.2	T509	T509-D511 PolarHBondContact O-N 3.05Å
512	K	35.4	Very low	30.8	Very low	186 Å²	186	137.1 Å²	137.1	81%	0.809	79%	0.785	S	S	*	*			trans	-87.1	108	170.3	-82.9	177.2	170.7	176.6	0	107.9
513	T	33.5	Very low	31.1	Very low	118 Å²	118	139.9 Å²	139.9	72%	0.724	79%	0.786	S	S	*	*			trans	167.8	112.4	157.6	36.7	0	0	0	0	104.1
514	D	30.5	Very low	31.3	Very low	160 Å²	160	143.2 Å²	143.2	86%	0.856	81%	0.806	S	S	*	*				-152.8	151.2	60.7	-80.2	-42	0	0	0	113.4
515	A	31.9	Very low	31.4	Very low	82 Å²	82	144.1 Å²	144.1	68%	0.678	81%	0.808	S	S	*	*			trans	-82.1	138.4	176.1	0	0	0	0	0	111.4
516	I	31.9	Very low	31.4	Very low	158 Å²	158	143.3 Å²	143.3	81%	0.81	81%	0.805	S	S	*	*			trans	59.1	107.4	139.9	-51.7	162	0	0	0	117.2
517	S	28	Very low	31.4	Very low	115 Å²	115	146.2 Å²	146.2	80%	0.804	80%	0.799	S	S	*	*				-149.6	118.5	126.9	60.7	0	0	0	0	111.1
518	F	32	Very low	31.7	Very low	187 Å²	187	151.2 Å²	151.2	82%	0.82	81%	0.808	S	S	*	*			trans	-65.8	137.7	160.3	-100.1	-102.1	0	0	0	108.9
519	T	31.1	Very low	31.6	Very low	139 Å²	139	147.8 Å²	147.8	85%	0.853	80%	0.802	S	S	*	*			trans	-163.3	122.2	131.6	23.8	0	0	0	0	110
520	E	33.1	Very low	31.8	Very low	163 Å²	163	149.4 Å²	149.4	76%	0.762	81%	0.805	S	S	*	*			trans	-68.2	161.2	166.4	-83.9	179	137.6	0	0	112.5
521	T	31.4	Very low	31.7	Very low	134 Å²	134	151.9 Å²	151.9	82%	0.822	81%	0.813	S	S	*	*			trans	69.3	116.4	153.2	49.8	0	0	0	0	119.4
522	S	30.2	Very low	32	Very low	97 Å²	97	151.9 Å²	151.9	68%	0.678	81%	0.813	S	S	*	*				162.5	128.4	92.1	-175	0	0	0	0	111.6
523	Q	33	Very low	31.7	Very low	162 Å²	162	149.1 Å²	149.1	76%	0.757	81%	0.814	S	S	*	*			trans	35.3	108.4	146	-61.2	178.8	-26.3	0	0	118.6
524	F	34.1	Very low	31.6	Very low	274 Å²	274	151.9 Å²	151.9	100%	1.202	82%	0.822	S	S	*	*				-171.1	0	95.2	-100.1	-76.5	0	0	0	110.1

Retrieved 524 of 524 residues in 500.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).