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Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.

AlphaFold DB , UniProt , Accession A0A087XIY2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 439 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.7	Very low	42.6	Very low	249 Å²	249	160.8 Å²	160.8	100%	1.227	88%	0.88	S	S	*	*				0	113.4	0	-68	-172.2	-143.4	0	0	108.8
2	A	38.9	Very low	43.8	Very low	106 Å²	106	156.4 Å²	156.4	88%	0.876	87%	0.87	S	S	*	*			trans	-164.7	108.1	156.1	0	0	0	0	0	106.5
3	G	36.7	Very low	44.8	Very low	77 Å²	77	151.4 Å²	151.4	79%	0.794	85%	0.848	S	S	*	*			trans	-73.4	133.9	-167.6	0	0	0	0	0	113.2	V5	G3-V5 PolarHBondContact O-N 3.32Å
4	G	37.5	Very low	45.9	Very low	78 Å²	78	145 Å²	145	80%	0.804	82%	0.819	S	S	*	*			trans	-68.5	120.6	168.9	0	0	0	0	0	111	R6	G4-R6 PolarHBondContact O-N 3.1Å
5	V	43.6	Very low	47.3	Very low	143 Å²	143	142.8 Å²	142.8	87%	0.867	81%	0.813	S	S	*	*			trans	-74.8	103.5	172.5	176.1	0	0	0	0	108.6	G3 R7	G3-V5 PolarHBondContact O-N 3.32Å; V5-R7 PolarHBondContact O-N 2.74Å
6	R	41.9	Very low	48.4	Very low	238 Å²	238	141.8 Å²	141.8	90%	0.898	80%	0.803	S	S	*	*			trans	-60.4	113.1	166.9	-92.4	179.1	169.5	175.7	-3	109.3	G4 K8	G4-R6 PolarHBondContact O-N 3.1Å; R6-K8 PolarHBondContact O-N 3.5Å; R6-K8 VanDerWaalsContact O-N 3.13Å
7	R	43.3	Very low	49.1	Very low	247 Å²	247	143.7 Å²	143.7	93%	0.932	80%	0.795	S	S	*	*			trans	-58.7	111.5	165.1	-110.5	176.1	161.8	173	-4.7	108.7	V5 S9	V5-R7 PolarHBondContact O-N 2.74Å; R7-S9 PolarHBondContact O-N 3.43Å
8	K	40.8	Very low	50	Low	203 Å²	203	137.6 Å²	137.6	88%	0.883	77%	0.77	S	S	*	*			trans	-56.6	124.1	167.3	-97.4	177.8	172.9	175.5	0	108.7	R6 R10	R6-K8 PolarHBondContact O-N 3.5Å; R6-K8 VanDerWaalsContact O-N 3.13Å; K8-R10 PolarHBondContact O-N 2.91Å
9	S	42.9	Very low	51	Low	111 Å²	111	137.9 Å²	137.9	78%	0.776	76%	0.762	S	S	*	*			trans	-58.5	129.7	165.9	51.9	0	0	0	0	108.5	R7 G11	R7-S9 PolarHBondContact O-N 3.43Å; S9-G11 PolarHBondContact O-N 2.67Å
10	R	47.8	Very low	51.9	Low	251 Å²	251	136.5 Å²	136.5	95%	0.947	75%	0.753	S	S	*	*			trans	-60	112.4	168	-86.3	177.4	167.4	170.7	-4.6	106.6	K8 S12	K8-R10 PolarHBondContact O-N 2.91Å; R10-S12 PolarHBondContact O-N 3.48Å
11	G	49.7	Very low	52.7	Low	66 Å²	66	134.9 Å²	134.9	68%	0.68	74%	0.739	S	S	*	*	P	Polyproline II helix	trans	-52.6	132.4	173.9	0	0	0	0	0	109.5	S9	S9-G11 PolarHBondContact O-N 2.67Å
12	S	57.3	Low	53.5	Low	108 Å²	108	126.5 Å²	126.5	76%	0.755	70%	0.703	S	S	*	*	P	Polyproline II helix	trans	-49.8	131	170	51.1	0	0	0	0	108.9	R10 S14	R10-S12 PolarHBondContact O-N 3.48Å; S12-S14 PolarHBondContact O-N 2.88Å
13	P	56	Low	54.8	Low	91 Å²	91	124.3 Å²	124.3	59%	0.591	68%	0.676	S	S	*	*	P	Polyproline II helix	trans	-55.2	141.2	176.6	22.2	-30.4	0	0	0	109.2	W17	P13-W17 HydrophobicContact CB-CE3 4.3Å
14	S	60.5	Low	56.3	Low	62 Å²	62	129.5 Å²	129.5	43%	0.434	67%	0.671	S	S	.	*	P	Polyproline II helix	trans	-54.9	144.6	-179.3	66.2	0	0	0	0	109.8	S12 L16 W17 G18	S12-S14 PolarHBondContact O-N 2.88Å; S14-L16 PolarHBondContact O-N 3.47Å; S14-W17 PolarHBondContact O-N 3.3Å; S14-W17 PolarHBondContact OG-N 3.28Å; S14-G18 PolarHBondContact O-N 2.92Å; S14-G18 VanDerWaalsContact O-N 3.16Å
15	P	67.2	Low	57.6	Low	112 Å²	112	131.7 Å²	131.7	73%	0.727	66%	0.661	S	S	*	*	H	α-helix	trans	-54.3	-28.6	-179.1	-24.5	31.6	0	0	0	113.1	K19	P15-K19 WeakPolarHBondContact O-CG 3.32Å; P15-K19 PolarHBondContact O-N 3.45Å; P15-K19 VanDerWaalsContact O-N 3.16Å
16	L	65.2	Low	58.7	Low	127 Å²	127	128.6 Å²	128.6	67%	0.665	64%	0.64	S	S	*	*	H	α-helix	trans	-68	-43.6	173.9	-86.4	157.3	0	0	0	112.7	S14 G18 K19 L20	S14-L16 PolarHBondContact O-N 3.47Å; L16-G18 VanDerWaalsContact C-N 3.35Å; L16-K19 PolarHBondContact O-N 3.5Å; L16-L20 WeakPolarHBondContact O-CB 3.4Å; L16-L20 PolarHBondContact O-N 3.34Å
17	W	59.5	Low	60.2	Low	174 Å²	174	122 Å²	122	66%	0.659	62%	0.618	S	S	*	*	H	α-helix	trans	-69.1	-35.9	179.7	-159.5	5.2	0	0	0	111.7	P13 S14 L20 H21	P13-W17 HydrophobicContact CB-CE3 4.3Å; S14-W17 PolarHBondContact O-N 3.3Å; S14-W17 PolarHBondContact OG-N 3.28Å; W17-L20 PolarHBondContact O-N 2.93Å; W17-H21 WeakPolarHBondContact O-CB 3.25Å; W17-H21 PolarHBondContact O-N 2.61Å
18	G	65.6	Low	61.4	Low	33 Å²	33	116.4 Å²	116.4	34%	0.34	60%	0.602	S	S	.	*	H	α-helix	trans	-61	-45.9	170.7	0	0	0	0	0	112.7	S14 L16 H21 T22	S14-G18 PolarHBondContact O-N 2.92Å; S14-G18 VanDerWaalsContact O-N 3.16Å; L16-G18 VanDerWaalsContact C-N 3.35Å; G18-H21 PolarHBondContact O-N 2.91Å; G18-T22 WeakPolarHBondContact O-CG2 3.26Å; G18-T22 PolarHBondContact O-N 3.17Å; G18-T22 PolarHBondContact O-OG1 3.3Å
19	K	68.5	Low	63	Low	144 Å²	144	109.6 Å²	109.6	63%	0.626	57%	0.574	S	S	*	*	H	α-helix	trans	-64.7	-38.6	175.6	-77.2	-178.9	178.8	-177.4	0	113.3	P15 L16 T22 L23	P15-K19 WeakPolarHBondContact O-CG 3.32Å; P15-K19 PolarHBondContact O-N 3.45Å; P15-K19 VanDerWaalsContact O-N 3.16Å; L16-K19 PolarHBondContact O-N 3.5Å; K19-T22 WeakPolarHBondContact CA-OG1 3.39Å; K19-T22 PolarHBondContact O-OG1 3.35Å; K19-L23 WeakPolarHBondContact O-CB 3.45Å; K19-L23 WeakPolarHBondContact O-CD1 3.24Å; K19-L23 VanDerWaalsContact O-CG 3.28Å; K19-L23 WeakPolarHBondContact O-CG 3.27Å; K19-L23 PolarHBondContact O-N 3.41Å
20	L	69.5	Low	64.7	Low	110 Å²	110	105.7 Å²	105.7	58%	0.576	55%	0.545	S	S	*	.	H	α-helix	trans	-67.2	-39	175.7	-90.8	148.9	0	0	0	111.8	L16 W17 W24	L16-L20 WeakPolarHBondContact O-CB 3.4Å; L16-L20 PolarHBondContact O-N 3.34Å; W17-L20 PolarHBondContact O-N 2.93Å; L20-W24 WeakPolarHBondContact O-CB 3.39Å; L20-W24 PolarHBondContact O-N 3.11Å
21	H	67.6	Low	66.2	Low	102 Å²	102	97.7 Å²	97.7	47%	0.472	52%	0.52	S	S	.	.	H	α-helix	trans	-69.1	-40.5	177.8	-166.9	-72.6	0	0	0	112.3	W17 G18 W24 Q25	W17-H21 WeakPolarHBondContact O-CB 3.25Å; W17-H21 PolarHBondContact O-N 2.61Å; G18-H21 PolarHBondContact O-N 2.91Å; H21-W24 PolarHBondContact O-N 3.33Å; H21-Q25 PolarHBondContact CE1-NE2 3.18Å; H21-Q25 WeakPolarHBondContact O-CG 3.23Å; H21-Q25 PolarHBondContact O-N 3.07Å
22	T	64.1	Low	67.7	Low	74 Å²	74	100.6 Å²	100.6	45%	0.454	51%	0.514	S	S	.	.	H	α-helix	trans	-67.1	-42	174.3	53.3	0	0	0	0	111.7	G18 K19 W24 Q25 D26	G18-T22 WeakPolarHBondContact O-CG2 3.26Å; G18-T22 PolarHBondContact O-N 3.17Å; G18-T22 PolarHBondContact O-OG1 3.3Å; K19-T22 WeakPolarHBondContact CA-OG1 3.39Å; K19-T22 PolarHBondContact O-OG1 3.35Å; T22-W24 VanDerWaalsContact C-N 3.26Å; T22-W24 PolarHBondContact O-N 3.34Å; T22-Q25 PolarHBondContact O-N 3.34Å; T22-D26 WeakPolarHBondContact O-CB 3.06Å; T22-D26 PolarHBondContact O-N 3.2Å
23	L	65.2	Low	68.9	Low	59 Å²	59	99.6 Å²	99.6	31%	0.309	50%	0.496	S	S	.	.	H	α-helix	trans	-58.9	-36.5	172	-80.9	165.6	0	0	0	112.7	K19 D26 K27 I30	K19-L23 WeakPolarHBondContact O-CB 3.45Å; K19-L23 WeakPolarHBondContact O-CD1 3.24Å; K19-L23 VanDerWaalsContact O-CG 3.28Å; K19-L23 WeakPolarHBondContact O-CG 3.27Å; K19-L23 PolarHBondContact O-N 3.41Å; L23-D26 CarbonylContact O-C 3.49Å; L23-K27 WeakPolarHBondContact O-CA 3.35Å; L23-K27 PolarHBondContact O-N 3.25Å; L23-I30 HydrophobicContact CD2-CD1 3.96Å; L23-I30 HydrophobicContact CD2-CG1 4.31Å
24	W	69.2	Low	70.2	Confident	186 Å²	186	97.2 Å²	97.2	71%	0.705	48%	0.48	S	S	*	.	H	α-helix	trans	-70.6	-39.7	177.2	-176.5	-94.3	0	0	0	112.7	L20 H21 T22 K27	L20-W24 WeakPolarHBondContact O-CB 3.39Å; L20-W24 PolarHBondContact O-N 3.11Å; H21-W24 PolarHBondContact O-N 3.33Å; T22-W24 VanDerWaalsContact C-N 3.26Å; T22-W24 PolarHBondContact O-N 3.34Å; W24-K27 WeakPolarHBondContact O-CG 3.25Å
25	Q	64.8	Low	71.2	Confident	124 Å²	124	101 Å²	101	58%	0.579	49%	0.491	S	S	*	.	H	α-helix	trans	-67.6	-37.7	174.9	-74.1	-176.9	-44	0	0	111.8	H21 T22	H21-Q25 PolarHBondContact CE1-NE2 3.18Å; H21-Q25 WeakPolarHBondContact O-CG 3.23Å; H21-Q25 PolarHBondContact O-N 3.07Å; T22-Q25 PolarHBondContact O-N 3.34Å
26	D	67.1	Low	72	Confident	79 Å²	79	97.8 Å²	97.8	42%	0.422	47%	0.466	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.6	19.8	-179.2	-72.6	-23.9	0	0	0	113.7	T22 L23 H28 L29	T22-D26 WeakPolarHBondContact O-CB 3.06Å; T22-D26 PolarHBondContact O-N 3.2Å; L23-D26 CarbonylContact O-C 3.49Å; D26-H28 PolarHBondContact O-N 3.42Å; D26-L29 HydrophobicContact CB-CB 4.4Å; D26-L29 HydrophobicContact CB-CD1 3.96Å; D26-L29 HydrophobicContact CB-CG 4.44Å; D26-L29 WeakPolarHBondContact O-CA 3.18Å; D26-L29 WeakPolarHBondContact O-CB 3.42Å; D26-L29 PolarHBondContact O-N 2.74Å
27	K	72.5	Confident	73	Confident	100 Å²	100	91.7 Å²	91.7	44%	0.435	43%	0.434	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.5	-31.9	-174.9	64.8	-175.8	176.7	-177.3	0	113.9	L23 W24 L29	L23-K27 WeakPolarHBondContact O-CA 3.35Å; L23-K27 PolarHBondContact O-N 3.25Å; W24-K27 WeakPolarHBondContact O-CG 3.25Å; K27-L29 VanDerWaalsContact C-N 3.34Å
28	H	69	Low	74.4	Confident	129 Å²	129	88.5 Å²	88.5	60%	0.597	43%	0.429	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.3	-32	177.6	-53.7	-70.8	0	0	0	111.9	D26 F32	D26-H28 PolarHBondContact O-N 3.42Å; H28-F32 WeakPolarHBondContact O-CD2 3.36Å
29	L	74.7	Confident	75.5	Confident	59 Å²	59	90.7 Å²	90.7	31%	0.309	43%	0.433	S	S	.	.	G	3₁₀ helix	trans	-76.5	-22.9	-178.2	-60.8	175.7	0	0	0	113	D26 K27 L31 F32 K33	D26-L29 HydrophobicContact CB-CB 4.4Å; D26-L29 HydrophobicContact CB-CD1 3.96Å; D26-L29 HydrophobicContact CB-CG 4.44Å; D26-L29 WeakPolarHBondContact O-CA 3.18Å; D26-L29 WeakPolarHBondContact O-CB 3.42Å; D26-L29 PolarHBondContact O-N 2.74Å; K27-L29 VanDerWaalsContact C-N 3.34Å; L29-L31 PolarHBondContact O-N 3.44Å; L29-F32 PolarHBondContact O-N 3.37Å; L29-F32 VanDerWaalsContact O-N 3.1Å; L29-K33 HydrophobicContact CB-CD 4.09Å; L29-K33 HydrophobicContact CB-CG 4.23Å; L29-K33 HydrophobicContact CD1-CD 4.45Å; L29-K33 WeakPolarHBondContact O-CB 3.27Å; L29-K33 PolarHBondContact O-N 3.1Å
30	I	78.3	Confident	76.4	Confident	30 Å²	30	84.6 Å²	84.6	15%	0.154	41%	0.408	C	S	.	.	G	3₁₀ helix	trans	-55.5	-38.9	179.4	-62.3	177.2	0	0	0	111.5	L23 H36 L39 V40	L23-I30 HydrophobicContact CD2-CD1 3.96Å; L23-I30 HydrophobicContact CD2-CG1 4.31Å; I30-H36 HydrophobicContact CG2-CB 4.14Å; I30-H36 WeakPolarHBondContact O-CB 3.26Å; I30-L39 HydrophobicContact CG2-CD2 4.35Å; I30-V40 HydrophobicContact CG2-CG2 3.9Å
31	L	79.3	Confident	77.5	Confident	82 Å²	82	79.7 Å²	79.7	43%	0.429	38%	0.382	S	S	.	.	G	3₁₀ helix	trans	-83.9	-18.6	-177	-68.2	-179	0	0	0	113.3	L29 V40 P146 Y147	L29-L31 PolarHBondContact O-N 3.44Å; L31-V40 HydrophobicContact CD2-CG2 4.46Å; L31-P146 WeakPolarHBondContact O-CD 3.38Å; L31-Y147 WeakPolarHBondContact O-CB 3.25Å; L31-Y147 WeakPolarHBondContact O-CD1 3.47Å; L31-Y147 PolarHBondContact O-N 2.8Å
32	F	81.4	Confident	78.6	Confident	127 Å²	127	77.6 Å²	77.6	56%	0.557	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	-110.6	-30.6	-174.3	-63.1	-70.6	0	0	0	114.2	H28 L29 P145 Y147	H28-F32 WeakPolarHBondContact O-CD2 3.36Å; L29-F32 PolarHBondContact O-N 3.37Å; L29-F32 VanDerWaalsContact O-N 3.1Å; F32-P145 WeakPolarHBondContact O-CB 3.45Å; F32-Y147 AromaticContact CD1-CD1 3.6Å; F32-Y147 HydrophobicContact CD1-CD1 3.6Å; F32-Y147 AromaticContact CD1-CE1 3.68Å; F32-Y147 HydrophobicContact CD1-CE1 3.68Å; F32-Y147 AromaticContact CE1-CD1 3.67Å; F32-Y147 HydrophobicContact CE1-CD1 3.67Å; F32-Y147 AromaticContact CE1-CE1 3.74Å; F32-Y147 HydrophobicContact CE1-CE1 3.74Å; F32-Y147 HydrophobicContact CE1-CG 4.42Å
33	K	81.6	Confident	79.9	Confident	88 Å²	88	77.8 Å²	77.8	38%	0.383	38%	0.38	S	S	.	.			trans	-86.5	127.6	179.6	-71.2	-170.7	175	-179.5	0	111.1	L29 E35 H36 P146	L29-K33 HydrophobicContact CB-CD 4.09Å; L29-K33 HydrophobicContact CB-CG 4.23Å; L29-K33 HydrophobicContact CD1-CD 4.45Å; L29-K33 WeakPolarHBondContact O-CB 3.27Å; L29-K33 PolarHBondContact O-N 3.1Å; K33-E35 PolarHBondContact O-N 3.22Å; K33-E35 VanDerWaalsContact O-N 3.09Å; K33-H36 PolarHBondContact O-N 3Å; K33-H36 VanDerWaalsContact O-N 3.12Å; K33-P146 VanDerWaalsContact O-CG 3.24Å; K33-P146 WeakPolarHBondContact O-CG 3.27Å
34	T	82.6	Confident	81.2	Confident	40 Å²	40	75.7 Å²	75.7	25%	0.245	37%	0.369	C	S	.	.	G	3₁₀ helix	trans	-64.1	-15.2	179.7	51.1	0	0	0	0	113.9	H36 T37 K142	T34-H36 PolarHBondContact O-N 3.49Å; T34-T37 WeakPolarHBondContact CA-OG1 3.48Å; T34-T37 VanDerWaalsContact O-CB 3.26Å; T34-T37 WeakPolarHBondContact O-CB 3.44Å; T34-T37 PolarHBondContact O-N 3.44Å; T34-T37 PolarHBondContact O-OG1 3.25Å; T34-K142 HydrophobicContact CG2-CB 4.41Å; T34-K142 WeakPolarHBondContact CG2-O 3.35Å
35	E	81.8	Confident	82.5	Confident	143 Å²	143	70 Å²	70	67%	0.668	35%	0.347	S	S	*	.	G	3₁₀ helix	trans	-62.5	-29.5	173.3	-65.8	170.4	-168.6	0	0	112.6	K33 T37	K33-E35 PolarHBondContact O-N 3.22Å; K33-E35 VanDerWaalsContact O-N 3.09Å; E35-T37 VanDerWaalsContact C-N 3.35Å
36	H	83.9	Confident	83.8	Confident	43 Å²	43	69.3 Å²	69.3	20%	0.199	35%	0.347	C	S	.	.	G	3₁₀ helix	trans	-93.7	8.4	179	-57.3	-62.6	0	0	0	113.3	I30 K33 T34 L38 L39 V40	I30-H36 HydrophobicContact CG2-CB 4.14Å; I30-H36 WeakPolarHBondContact O-CB 3.26Å; K33-H36 PolarHBondContact O-N 3Å; K33-H36 VanDerWaalsContact O-N 3.12Å; T34-H36 PolarHBondContact O-N 3.49Å; H36-L38 VanDerWaalsContact C-N 3.33Å; H36-L38 PolarHBondContact O-N 2.9Å; H36-L39 PolarHBondContact O-N 3.28Å; H36-L39 VanDerWaalsContact O-N 3.16Å; H36-V40 PolarHBondContact O-N 3.44Å; H36-V40 VanDerWaalsContact O-N 3.13Å
37	T	87.4	Confident	85.1	Confident	0 Å²	0	70 Å²	70	0%	0	35%	0.35	C	S	.	.	H	α-helix	trans	-52.2	-50.6	-179.5	-63.4	0	0	0	0	111.4	T34 E35 L39 V40 V41 N139 F149	T34-T37 WeakPolarHBondContact CA-OG1 3.48Å; T34-T37 VanDerWaalsContact O-CB 3.26Å; T34-T37 WeakPolarHBondContact O-CB 3.44Å; T34-T37 PolarHBondContact O-N 3.44Å; T34-T37 PolarHBondContact O-OG1 3.25Å; E35-T37 VanDerWaalsContact C-N 3.35Å; T37-L39 VanDerWaalsContact C-N 3.29Å; T37-L39 PolarHBondContact O-N 3.19Å; T37-V40 PolarHBondContact O-N 3.03Å; T37-V41 HydrophobicContact CG2-CG1 4.05Å; T37-V41 WeakPolarHBondContact O-CG1 3.18Å; T37-V41 VanDerWaalsContact O-CG2 3.29Å; T37-V41 WeakPolarHBondContact O-CG2 3.38Å; T37-V41 PolarHBondContact O-N 3.48Å; T37-N139 HydrophobicContact CG2-CB 3.95Å; T37-F149 HydrophobicContact CG2-CD2 4.43Å; T37-F149 HydrophobicContact CG2-CE2 3.51Å; T37-F149 HydrophobicContact CG2-CZ 4.05Å
38	L	88.8	Confident	86.1	Confident	106 Å²	106	65.2 Å²	65.2	56%	0.555	33%	0.329	S	S	*	.	H	α-helix	trans	-58.1	-40.3	-177.6	-172.2	67	0	0	0	112.7	H36 V41 S42	H36-L38 VanDerWaalsContact C-N 3.33Å; H36-L38 PolarHBondContact O-N 2.9Å; L38-V41 WeakPolarHBondContact O-CG2 3.45Å; L38-S42 VanDerWaalsContact O-CB 3.3Å; L38-S42 WeakPolarHBondContact O-CB 3.49Å; L38-S42 PolarHBondContact O-N 3.35Å; L38-S42 PolarHBondContact O-OG 3.48Å
39	L	87.8	Confident	87.3	Confident	80 Å²	80	62 Å²	62	42%	0.419	32%	0.315	S	S	.	.	H	α-helix	trans	-64.6	-51.7	178.1	-177.3	158.5	0	0	0	110.3	I30 H36 T37 V41 S42 V43	I30-L39 HydrophobicContact CG2-CD2 4.35Å; H36-L39 PolarHBondContact O-N 3.28Å; H36-L39 VanDerWaalsContact O-N 3.16Å; T37-L39 VanDerWaalsContact C-N 3.29Å; T37-L39 PolarHBondContact O-N 3.19Å; L39-V41 PolarHBondContact O-N 2.89Å; L39-S42 PolarHBondContact O-N 3.47Å; L39-V43 HydrophobicContact CD2-CG2 4.49Å; L39-V43 WeakPolarHBondContact O-CG2 3.47Å; L39-V43 PolarHBondContact O-N 2.77Å; L39-V43 VanDerWaalsContact O-N 3.14Å
40	V	89.1	Confident	88.3	Confident	15 Å²	15	61.1 Å²	61.1	9%	0.091	32%	0.321	C	S	.	.	H	α-helix	trans	-62.2	-46.7	-177.2	175	0	0	0	0	110.9	I30 L31 H36 T37 S42 V43 L44 P146	I30-V40 HydrophobicContact CG2-CG2 3.9Å; L31-V40 HydrophobicContact CD2-CG2 4.46Å; H36-V40 PolarHBondContact O-N 3.44Å; H36-V40 VanDerWaalsContact O-N 3.13Å; T37-V40 PolarHBondContact O-N 3.03Å; V40-S42 VanDerWaalsContact C-N 3.33Å; V40-S42 PolarHBondContact O-N 3.31Å; V40-V43 PolarHBondContact O-N 3.34Å; V40-L44 HydrophobicContact CG1-CD1 3.85Å; V40-L44 HydrophobicContact CG1-CG 4.36Å; V40-L44 WeakPolarHBondContact O-CG 3.42Å; V40-L44 PolarHBondContact O-N 3.28Å; V40-P146 HydrophobicContact CB-CB 3.91Å; V40-P146 HydrophobicContact CG1-CB 4.04Å; V40-P146 HydrophobicContact CG2-CB 3.73Å
41	V	91.1	Very high	89	Confident	8 Å²	8	62.3 Å²	62.3	5%	0.048	33%	0.327	C	S	.	.	H	α-helix	trans	-67.2	-32.9	179.8	-58.6	0	0	0	0	112.5	T37 L38 L39 L44 W45 F135 F149	T37-V41 HydrophobicContact CG2-CG1 4.05Å; T37-V41 WeakPolarHBondContact O-CG1 3.18Å; T37-V41 VanDerWaalsContact O-CG2 3.29Å; T37-V41 WeakPolarHBondContact O-CG2 3.38Å; T37-V41 PolarHBondContact O-N 3.48Å; L38-V41 WeakPolarHBondContact O-CG2 3.45Å; L39-V41 PolarHBondContact O-N 2.89Å; V41-L44 PolarHBondContact O-N 3.4Å; V41-W45 WeakPolarHBondContact O-CB 3.42Å; V41-W45 PolarHBondContact O-N 3.36Å; V41-F135 HydrophobicContact CB-CB 4.06Å; V41-F135 HydrophobicContact CB-CD1 3.95Å; V41-F135 HydrophobicContact CB-CD2 3.67Å; V41-F135 HydrophobicContact CB-CE1 4.18Å; V41-F135 HydrophobicContact CB-CE2 3.89Å; V41-F135 HydrophobicContact CB-CG 3.66Å; V41-F135 HydrophobicContact CB-CZ 4.09Å; V41-F135 HydrophobicContact CG1-CB 4.12Å; V41-F135 HydrophobicContact CG1-CD1 3.54Å; V41-F135 HydrophobicContact CG1-CD2 4.23Å; V41-F135 HydrophobicContact CG1-CE1 3.82Å; V41-F135 HydrophobicContact CG1-CE2 4.44Å; V41-F135 HydrophobicContact CG1-CG 3.73Å; V41-F135 HydrophobicContact CG1-CZ 4.21Å; V41-F135 HydrophobicContact CG2-CB 4.2Å; V41-F135 HydrophobicContact CG2-CD2 4.38Å; V41-F135 HydrophobicContact CG2-CG 4.32Å; V41-F149 HydrophobicContact CG1-CB 4.46Å; V41-F149 HydrophobicContact CG1-CD2 3.47Å; V41-F149 VanDerWaalsContact CG1-CD2 3.47Å; V41-F149 HydrophobicContact CG1-CE2 3.91Å; V41-F149 HydrophobicContact CG1-CG 4Å
42	S	91.2	Very high	89.7	Confident	57 Å²	57	58.5 Å²	58.5	40%	0.399	31%	0.307	S	S	.	.	H	α-helix	trans	-65.4	-43.6	176.4	-60.1	0	0	0	0	111.4	L38 L39 V40 W45 I46	L38-S42 VanDerWaalsContact O-CB 3.3Å; L38-S42 WeakPolarHBondContact O-CB 3.49Å; L38-S42 PolarHBondContact O-N 3.35Å; L38-S42 PolarHBondContact O-OG 3.48Å; L39-S42 PolarHBondContact O-N 3.47Å; V40-S42 VanDerWaalsContact C-N 3.33Å; V40-S42 PolarHBondContact O-N 3.31Å; S42-W45 PolarHBondContact O-N 2.87Å; S42-I46 WeakPolarHBondContact O-CG1 3.38Å; S42-I46 PolarHBondContact O-N 2.81Å; S42-I46 VanDerWaalsContact O-N 3.16Å
43	V	92.3	Very high	90.4	Very high	79 Å²	79	56 Å²	56	48%	0.479	30%	0.299	S	S	.	.	H	α-helix	trans	-64.3	-48.8	176	174.1	0	0	0	0	110.5	L39 V40 W45 I46 L47	L39-V43 HydrophobicContact CD2-CG2 4.49Å; L39-V43 WeakPolarHBondContact O-CG2 3.47Å; L39-V43 PolarHBondContact O-N 2.77Å; L39-V43 VanDerWaalsContact O-N 3.14Å; V40-V43 PolarHBondContact O-N 3.34Å; V43-W45 VanDerWaalsContact C-N 3.31Å; V43-W45 PolarHBondContact O-N 3.4Å; V43-I46 PolarHBondContact O-N 2.88Å; V43-L47 HydrophobicContact CG1-CD1 4.12Å; V43-L47 WeakPolarHBondContact O-CG 3.34Å; V43-L47 PolarHBondContact O-N 3.31Å
44	L	92.6	Very high	91	Very high	15 Å²	15	59 Å²	59	8%	0.079	31%	0.308	C	S	.	.	H	α-helix	trans	-59.6	-42.6	178.7	-70.5	174.1	0	0	0	111.7	V40 V41 I46 L47 E48 F135 F149 F150	V40-L44 HydrophobicContact CG1-CD1 3.85Å; V40-L44 HydrophobicContact CG1-CG 4.36Å; V40-L44 WeakPolarHBondContact O-CG 3.42Å; V40-L44 PolarHBondContact O-N 3.28Å; V41-L44 PolarHBondContact O-N 3.4Å; L44-I46 PolarHBondContact O-N 3Å; L44-L47 WeakPolarHBondContact O-CB 3.28Å; L44-L47 PolarHBondContact O-N 3.49Å; L44-E48 VanDerWaalsContact O-CG 3.3Å; L44-E48 WeakPolarHBondContact O-CG 3.41Å; L44-E48 PolarHBondContact O-N 2.88Å; L44-F135 HydrophobicContact CB-CZ 4.43Å; L44-F149 HydrophobicContact CD1-CB 3.6Å; L44-F150 HydrophobicContact CD2-CD2 4.45Å
45	W	94.4	Very high	91.6	Very high	66 Å²	66	57.6 Å²	57.6	25%	0.25	30%	0.3	C	S	.	.	H	α-helix	trans	-62.2	-40.7	178.8	-170.8	83.6	0	0	0	112.8	V41 S42 V43 E48 I49 L128 L132 F135	V41-W45 WeakPolarHBondContact O-CB 3.42Å; V41-W45 PolarHBondContact O-N 3.36Å; S42-W45 PolarHBondContact O-N 2.87Å; V43-W45 VanDerWaalsContact C-N 3.31Å; V43-W45 PolarHBondContact O-N 3.4Å; W45-E48 PolarHBondContact O-N 2.73Å; W45-I49 HydrophobicContact CE3-CD1 4.08Å; W45-I49 HydrophobicContact CH2-CD1 3.93Å; W45-I49 HydrophobicContact CZ3-CD1 3.61Å; W45-I49 HydrophobicContact CZ3-CG1 4.44Å; W45-I49 PolarHBondContact O-N 3.4Å; W45-L128 HydrophobicContact CZ2-CB 4.03Å; W45-L128 HydrophobicContact CZ2-CD2 4.48Å; W45-L128 PolarHBondContact NE1-O 2.87Å; W45-L132 HydrophobicContact CD2-CD2 4.05Å; W45-L132 HydrophobicContact CG-CD2 3.95Å; W45-L132 HydrophobicContact CZ2-CD1 3.88Å; W45-L132 HydrophobicContact CZ2-CD2 4.5Å; W45-L132 HydrophobicContact CZ2-CG 4.28Å; W45-L132 VanDerWaalsContact NE1-CG 3.34Å; W45-F135 HydrophobicContact CB-CE2 4.12Å
46	I	94	Very high	92.3	Very high	110 Å²	110	50.9 Å²	50.9	56%	0.564	27%	0.268	S	S	*	.	H	α-helix	trans	-63.9	-42.2	174.6	-67.7	167.6	0	0	0	110.8	S42 V43 L44 E48 I49	S42-I46 WeakPolarHBondContact O-CG1 3.38Å; S42-I46 PolarHBondContact O-N 2.81Å; S42-I46 VanDerWaalsContact O-N 3.16Å; V43-I46 PolarHBondContact O-N 2.88Å; L44-I46 PolarHBondContact O-N 3Å; I46-E48 VanDerWaalsContact C-N 3.3Å; I46-E48 PolarHBondContact O-N 2.94Å; I46-I49 WeakPolarHBondContact O-CB 3.34Å; I46-I49 PolarHBondContact O-N 3.27Å
47	L	93.1	Very high	92.8	Very high	93 Å²	93	54.3 Å²	54.3	49%	0.487	28%	0.284	S	S	.	.	H	α-helix	trans	-62.8	-38.3	176.7	-68.1	173.5	0	0	0	111.9	V43 L44 I49 G50 I51	V43-L47 HydrophobicContact CG1-CD1 4.12Å; V43-L47 WeakPolarHBondContact O-CG 3.34Å; V43-L47 PolarHBondContact O-N 3.31Å; L44-L47 WeakPolarHBondContact O-CB 3.28Å; L44-L47 PolarHBondContact O-N 3.49Å; L47-I49 VanDerWaalsContact C-N 3.25Å; L47-I49 PolarHBondContact O-N 3.37Å; L47-G50 WeakPolarHBondContact O-CA 3.25Å; L47-G50 PolarHBondContact O-N 2.97Å; L47-I51 WeakPolarHBondContact O-CG1 3.37Å; L47-I51 PolarHBondContact O-N 2.78Å
48	E	93.9	Very high	93.1	Very high	0 Å²	0	61.5 Å²	61.5	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-62.8	-29	178.1	-75.7	-66	136.8	0	0	113	L44 W45 I46 I51 N52 Y127 L128 L131 C153 H160	L44-E48 VanDerWaalsContact O-CG 3.3Å; L44-E48 WeakPolarHBondContact O-CG 3.41Å; L44-E48 PolarHBondContact O-N 2.88Å; W45-E48 PolarHBondContact O-N 2.73Å; I46-E48 VanDerWaalsContact C-N 3.3Å; I46-E48 PolarHBondContact O-N 2.94Å; E48-I51 PolarHBondContact O-N 3.46Å; E48-I51 WeakPolarHBondContact OE1-CD1 3.28Å; E48-N52 WeakPolarHBondContact O-CB 3.41Å; E48-N52 PolarHBondContact O-N 3.43Å; E48-N52 PolarHBondContact O-ND2 2.88Å; E48-Y127 HydrophobicContact CB-CE1 4.33Å; E48-Y127 HydrophobicContact CG-CE1 4.48Å; E48-Y127 WeakPolarHBondContact OE2-CE1 3.17Å; E48-Y127 VanDerWaalsContact OE2-CZ 3.27Å; E48-Y127 PolarHBondContact OE2-OH 2.84Å; E48-L128 HydrophobicContact CB-CD2 4.01Å; E48-L131 HydrophobicContact CB-CD1 4.07Å; E48-L131 HydrophobicContact CG-CD1 3.77Å; E48-C153 HydrophobicContact CG-CB 3.89Å; E48-C153 VanDerWaalsContact OE1-C 3.26Å; E48-C153 VanDerWaalsContact OE1-CB 3.24Å; E48-C153 WeakPolarHBondContact OE1-CB 3.47Å; E48-H160 IonicContact OE2-CE1 3.4Å; E48-H160 IonicContact OE2-NE2 3.51Å; E48-H160 PolarHBondContact OE2-NE2 2.92Å
49	I	94.8	Very high	93.4	Very high	60 Å²	60	58.5 Å²	58.5	31%	0.308	30%	0.302	S	S	.	.	H	α-helix	trans	-59.5	-50.1	169.8	-59.9	171.8	0	0	0	109.7	W45 I46 L47 I51 N52 L53 L128	W45-I49 HydrophobicContact CE3-CD1 4.08Å; W45-I49 HydrophobicContact CH2-CD1 3.93Å; W45-I49 HydrophobicContact CZ3-CD1 3.61Å; W45-I49 HydrophobicContact CZ3-CG1 4.44Å; W45-I49 PolarHBondContact O-N 3.4Å; I46-I49 WeakPolarHBondContact O-CB 3.34Å; I46-I49 PolarHBondContact O-N 3.27Å; L47-I49 VanDerWaalsContact C-N 3.25Å; L47-I49 PolarHBondContact O-N 3.37Å; I49-I51 PolarHBondContact O-N 3.32Å; I49-N52 PolarHBondContact O-N 2.98Å; I49-L53 HydrophobicContact CG2-CD1 4.18Å; I49-L53 VanDerWaalsContact O-CG 3.32Å; I49-L53 WeakPolarHBondContact O-CG 3.38Å; I49-L53 PolarHBondContact O-N 3.3Å; I49-L53 VanDerWaalsContact O-N 3.07Å; I49-L128 HydrophobicContact CG1-CD1 3.85Å; I49-L128 HydrophobicContact CG1-CD2 3.97Å
50	G	94.4	Very high	93.6	Very high	42 Å²	42	58.5 Å²	58.5	43%	0.433	31%	0.313	S	S	.	.	H	α-helix	trans	-62.1	-42.2	178.9	0	0	0	0	0	112.6	L47 L53 W54	L47-G50 WeakPolarHBondContact O-CA 3.25Å; L47-G50 PolarHBondContact O-N 2.97Å; G50-L53 PolarHBondContact O-N 3.48Å; G50-W54 WeakPolarHBondContact O-CB 3.49Å; G50-W54 PolarHBondContact O-N 2.93Å
51	I	93.5	Very high	93.8	Very high	54 Å²	54	60.5 Å²	60.5	28%	0.277	32%	0.32	S	S	.	.	H	α-helix	trans	-63.3	-47	177.9	-66.5	167.7	0	0	0	110.7	L47 E48 I49 L53 W54 V55 H160	L47-I51 WeakPolarHBondContact O-CG1 3.37Å; L47-I51 PolarHBondContact O-N 2.78Å; E48-I51 PolarHBondContact O-N 3.46Å; E48-I51 WeakPolarHBondContact OE1-CD1 3.28Å; I49-I51 PolarHBondContact O-N 3.32Å; I51-L53 PolarHBondContact O-N 2.78Å; I51-W54 PolarHBondContact O-N 3.17Å; I51-V55 HydrophobicContact CG2-CG2 4.21Å; I51-V55 WeakPolarHBondContact O-CG2 3.42Å; I51-V55 PolarHBondContact O-N 2.94Å; I51-H160 WeakPolarHBondContact CG2-NE2 3.21Å
52	N	94.6	Very high	93.8	Very high	3 Å²	3	63 Å²	63	2%	0.016	34%	0.335	C	S	.	.	H	α-helix	trans	-61.8	-43.8	178.8	-84	-88.4	0	0	0	111.7	E48 I49 W54 V55 I56 A124 Y127 V164	E48-N52 WeakPolarHBondContact O-CB 3.41Å; E48-N52 PolarHBondContact O-N 3.43Å; E48-N52 PolarHBondContact O-ND2 2.88Å; I49-N52 PolarHBondContact O-N 2.98Å; N52-W54 VanDerWaalsContact C-N 3.33Å; N52-W54 PolarHBondContact O-N 3.45Å; N52-V55 PolarHBondContact O-N 2.85Å; N52-I56 WeakPolarHBondContact O-CB 3.46Å; N52-I56 WeakPolarHBondContact O-CD1 3.32Å; N52-I56 WeakPolarHBondContact O-CG1 3.34Å; N52-I56 PolarHBondContact O-N 3.36Å; N52-A124 HydrophobicContact CB-CB 4.11Å; N52-Y127 WeakPolarHBondContact ND2-CD1 3.25Å; N52-Y127 WeakPolarHBondContact ND2-CE1 3.43Å; N52-V164 WeakPolarHBondContact OD1-CG1 3.3Å
53	L	95.3	Very high	93.8	Very high	73 Å²	73	63.2 Å²	63.2	38%	0.382	33%	0.33	S	S	.	.	H	α-helix	trans	-60.8	-43	174.9	-68.5	175.8	0	0	0	111.8	I49 G50 I51 I56 Q57 Y121	I49-L53 HydrophobicContact CG2-CD1 4.18Å; I49-L53 VanDerWaalsContact O-CG 3.32Å; I49-L53 WeakPolarHBondContact O-CG 3.38Å; I49-L53 PolarHBondContact O-N 3.3Å; I49-L53 VanDerWaalsContact O-N 3.07Å; G50-L53 PolarHBondContact O-N 3.48Å; I51-L53 PolarHBondContact O-N 2.78Å; L53-I56 PolarHBondContact O-N 2.93Å; L53-Q57 WeakPolarHBondContact O-CB 3.34Å; L53-Q57 VanDerWaalsContact O-CG 3.24Å; L53-Q57 WeakPolarHBondContact O-CG 3.36Å; L53-Q57 PolarHBondContact O-N 2.98Å; L53-Y121 HydrophobicContact CD2-CD1 4.29Å; L53-Y121 HydrophobicContact CD2-CE1 3.8Å
54	W	94.9	Very high	93.7	Very high	151 Å²	151	62.6 Å²	62.6	57%	0.572	32%	0.323	S	S	*	.	H	α-helix	trans	-62.9	-47.4	176.9	177.8	85.5	0	0	0	112	G50 I51 N52 I56 Q57 K58	G50-W54 WeakPolarHBondContact O-CB 3.49Å; G50-W54 PolarHBondContact O-N 2.93Å; I51-W54 PolarHBondContact O-N 3.17Å; N52-W54 VanDerWaalsContact C-N 3.33Å; N52-W54 PolarHBondContact O-N 3.45Å; W54-I56 PolarHBondContact O-N 3.44Å; W54-Q57 PolarHBondContact O-N 2.86Å; W54-K58 HydrophobicContact CG-CG 4.34Å; W54-K58 HydrophobicContact CZ2-CB 4.47Å; W54-K58 VanDerWaalsContact O-CB 3.29Å; W54-K58 WeakPolarHBondContact O-CB 3.38Å; W54-K58 WeakPolarHBondContact O-CG 3.4Å; W54-K58 PolarHBondContact O-N 2.76Å
55	V	94.7	Very high	93.7	Very high	12 Å²	12	62.7 Å²	62.7	7%	0.073	32%	0.323	C	S	.	.	H	α-helix	trans	-59	-47.8	177.8	170.8	0	0	0	0	110.5	I51 N52 Q57 K58 V59 V164 L165	I51-V55 HydrophobicContact CG2-CG2 4.21Å; I51-V55 WeakPolarHBondContact O-CG2 3.42Å; I51-V55 PolarHBondContact O-N 2.94Å; N52-V55 PolarHBondContact O-N 2.85Å; V55-Q57 VanDerWaalsContact C-N 3.28Å; V55-Q57 PolarHBondContact O-N 2.81Å; V55-K58 PolarHBondContact O-N 3.1Å; V55-V59 HydrophobicContact CG1-CB 4.27Å; V55-V59 HydrophobicContact CG1-CG2 4.23Å; V55-V59 WeakPolarHBondContact O-CB 3.39Å; V55-V59 PolarHBondContact O-N 3.49Å; V55-V164 HydrophobicContact CB-CG2 4.47Å; V55-V164 HydrophobicContact CG1-CG2 3.75Å; V55-L165 HydrophobicContact CG1-CD1 4.05Å; V55-L165 HydrophobicContact CG1-CD2 3.94Å; V55-L165 HydrophobicContact CG1-CG 4.02Å
56	I	95.9	Very high	93.8	Very high	1 Å²	1	59.6 Å²	59.6	1%	0.005	31%	0.312	C	S	.	.	H	α-helix	trans	-59.6	-41.4	179	-68.3	168.4	0	0	0	110.7	N52 L53 W54 R117 Q120 Y121 A124 V164	N52-I56 WeakPolarHBondContact O-CB 3.46Å; N52-I56 WeakPolarHBondContact O-CD1 3.32Å; N52-I56 WeakPolarHBondContact O-CG1 3.34Å; N52-I56 PolarHBondContact O-N 3.36Å; L53-I56 PolarHBondContact O-N 2.93Å; W54-I56 PolarHBondContact O-N 3.44Å; I56-R117 PolarHBondContact O-NH1 3.23Å; I56-Q120 HydrophobicContact CD1-CB 4.13Å; I56-Q120 HydrophobicContact CG1-CB 4.08Å; I56-Q120 HydrophobicContact CG2-CB 4.23Å; I56-Y121 HydrophobicContact CD1-CD1 3.73Å; I56-Y121 HydrophobicContact CD1-CE1 3.97Å; I56-Y121 HydrophobicContact CG2-CE1 3.99Å; I56-A124 HydrophobicContact CD1-CB 4Å; I56-V164 HydrophobicContact CG1-CB 4.21Å; I56-V164 HydrophobicContact CG1-CG2 4.44Å
57	Q	94.9	Very high	93.8	Very high	115 Å²	115	60.1 Å²	60.1	54%	0.537	31%	0.31	S	S	.	.	H	α-helix	trans	-78.7	-31.4	-177.2	-70.3	175.1	13.6	0	0	114.1	L53 W54 V55	L53-Q57 WeakPolarHBondContact O-CB 3.34Å; L53-Q57 VanDerWaalsContact O-CG 3.24Å; L53-Q57 WeakPolarHBondContact O-CG 3.36Å; L53-Q57 PolarHBondContact O-N 2.98Å; W54-Q57 PolarHBondContact O-N 2.86Å; V55-Q57 VanDerWaalsContact C-N 3.28Å; V55-Q57 PolarHBondContact O-N 2.81Å
58	K	94.6	Very high	93.9	Very high	151 Å²	151	55.7 Å²	55.7	66%	0.657	29%	0.287	S	S	*	.	H	α-helix	trans	-110.6	-19.5	-167.9	-62.2	-61.2	-175.1	179.8	0	114.6	W54 V55	W54-K58 HydrophobicContact CG-CG 4.34Å; W54-K58 HydrophobicContact CZ2-CB 4.47Å; W54-K58 VanDerWaalsContact O-CB 3.29Å; W54-K58 WeakPolarHBondContact O-CB 3.38Å; W54-K58 WeakPolarHBondContact O-CG 3.4Å; W54-K58 PolarHBondContact O-N 2.76Å; V55-K58 PolarHBondContact O-N 3.1Å
59	V	93.8	Very high	94	Very high	44 Å²	44	55.8 Å²	55.8	27%	0.267	29%	0.287	S	S	.	.	S	Bend	trans	-108.3	132.5	-179.6	-171.5	0	0	0	0	109.6	V55 Y61 L165	V55-V59 HydrophobicContact CG1-CB 4.27Å; V55-V59 HydrophobicContact CG1-CG2 4.23Å; V55-V59 WeakPolarHBondContact O-CB 3.39Å; V55-V59 PolarHBondContact O-N 3.49Å; V59-Y61 PolarHBondContact O-N 3.41Å; V59-L165 HydrophobicContact CB-CD1 4.12Å; V59-L165 HydrophobicContact CB-CD2 4.2Å; V59-L165 HydrophobicContact CG1-CD1 3.52Å; V59-L165 HydrophobicContact CG1-CD2 4.25Å
60	A	93	Very high	94.1	Very high	79 Å²	79	53.3 Å²	53.3	65%	0.653	28%	0.275	S	S	*	.			trans	-64	136.1	178.7	0	0	0	0	0	111.1
61	Y	93.6	Very high	94.2	Very high	58 Å²	58	54.1 Å²	54.1	23%	0.227	27%	0.269	C	S	.	.			trans	-61.4	140.4	169.5	172.8	-105.9	0	0	0	110.3	V59 E63 W66 I116 L165 L167	V59-Y61 PolarHBondContact O-N 3.41Å; Y61-E63 HydrophobicContact CE1-CB 3.8Å; Y61-E63 WeakPolarHBondContact CE1-OE2 3.18Å; Y61-E63 VanDerWaalsContact CZ-OE2 3.26Å; Y61-E63 VanDerWaalsContact OH-CD 3.28Å; Y61-E63 PolarHBondContact OH-OE2 3.3Å; Y61-W66 WeakPolarHBondContact OH-CB 3.44Å; Y61-I116 HydrophobicContact CD1-CG2 3.93Å; Y61-I116 HydrophobicContact CD2-CG2 3.77Å; Y61-I116 HydrophobicContact CE1-CG2 3.99Å; Y61-I116 HydrophobicContact CE2-CG2 3.87Å; Y61-I116 HydrophobicContact CG-CG2 3.81Å; Y61-L165 WeakPolarHBondContact CD2-O 3.2Å; Y61-L165 WeakPolarHBondContact CE2-O 3.23Å; Y61-L167 HydrophobicContact CE2-CD1 3.95Å; Y61-L167 HydrophobicContact CE2-CG 4.08Å
62	T	91.4	Very high	94.3	Very high	61 Å²	61	51.7 Å²	51.7	37%	0.374	26%	0.257	S	S	.	.			trans	-121.7	105	178.2	-54	0	0	0	0	109	I64 L165	T62-I64 HydrophobicContact CG2-CG1 4.39Å; T62-I64 PolarHBondContact O-N 3.25Å; T62-L165 PolarHBondContact N-O 3.15Å; T62-L165 VanDerWaalsContact O-O 3.07Å
63	E	90.9	Very high	94.4	Very high	60 Å²	60	51.6 Å²	51.6	28%	0.28	26%	0.256	S	S	.	.			trans	-65.9	128.2	176.3	-175	55.5	-122.7	0	0	110.6	Y61 W66 K67	Y61-E63 HydrophobicContact CE1-CB 3.8Å; Y61-E63 WeakPolarHBondContact CE1-OE2 3.18Å; Y61-E63 VanDerWaalsContact CZ-OE2 3.26Å; Y61-E63 VanDerWaalsContact OH-CD 3.28Å; Y61-E63 PolarHBondContact OH-OE2 3.3Å; E63-W66 WeakPolarHBondContact OE1-CA 3.39Å; E63-W66 WeakPolarHBondContact OE1-CB 3.48Å; E63-W66 PolarHBondContact OE1-N 3.33Å; E63-K67 HydrophobicContact CG-CD 4.02Å; E63-K67 HydrophobicContact CG-CG 4.14Å; E63-K67 PolarHBondContact OE1-N 3.46Å
64	I	90.4	Very high	94.4	Very high	67 Å²	67	51.1 Å²	51.1	34%	0.344	25%	0.252	S	S	.	.	S	Bend	trans	-133.1	-69	169.9	-58.2	-168.8	0	0	0	108.3	T62 T90 R166 F168	T62-I64 HydrophobicContact CG2-CG1 4.39Å; T62-I64 PolarHBondContact O-N 3.25Å; I64-T90 WeakPolarHBondContact O-CG2 3.33Å; I64-R166 HydrophobicContact CD1-CG 4.3Å; I64-R166 VanDerWaalsContact CD1-NE 3.35Å; I64-F168 HydrophobicContact CB-CE1 4.13Å; I64-F168 HydrophobicContact CB-CZ 4.15Å; I64-F168 HydrophobicContact CD1-CZ 4.12Å; I64-F168 HydrophobicContact CG2-CE1 4.01Å; I64-F168 HydrophobicContact CG2-CZ 4.04Å
65	D	92.4	Very high	94.5	Very high	16 Å²	16	44.8 Å²	44.8	9%	0.086	23%	0.233	C	C	.	.	S	Bend	trans	-115.6	-9.6	-172.5	-77.3	-17.6	0	0	0	114	K67 A68 Y69 T90 F168	D65-K67 PolarHBondContact O-N 2.7Å; D65-A68 PolarHBondContact O-N 3.03Å; D65-Y69 HydrophobicContact CB-CD1 4.16Å; D65-Y69 HydrophobicContact CB-CD2 4.36Å; D65-Y69 HydrophobicContact CB-CE1 3.55Å; D65-Y69 HydrophobicContact CB-CE2 3.82Å; D65-Y69 WeakPolarHBondContact CB-OH 3.39Å; D65-Y69 VanDerWaalsContact O-CD1 3.31Å; D65-Y69 WeakPolarHBondContact O-CD1 3.36Å; D65-Y69 WeakPolarHBondContact O-CD2 3.37Å; D65-Y69 PolarHBondContact O-N 2.9Å; D65-Y69 PolarHBondContact OD2-OH 3.49Å; D65-T90 PolarHBondContact OD1-OG1 3.12Å; D65-T90 VanDerWaalsContact OD1-OG1 3.06Å; D65-F168 HydrophobicContact CB-CD1 4.01Å; D65-F168 HydrophobicContact CB-CE1 3.85Å; D65-F168 VanDerWaalsContact OD2-CE1 3.24Å; D65-F168 WeakPolarHBondContact OD2-CE1 3.44Å
66	W	95.5	Very high	94.5	Very high	1 Å²	1	44.8 Å²	44.8	0%	0.004	23%	0.233	C	C	.	.	H	α-helix	trans	-61.4	-47.5	-173.6	174.6	-100	0	0	0	111.9	Y61 E63 A68 Y69 M70 F103 L106 T110 G113 I116 F123 L167	Y61-W66 WeakPolarHBondContact OH-CB 3.44Å; E63-W66 WeakPolarHBondContact OE1-CA 3.39Å; E63-W66 WeakPolarHBondContact OE1-CB 3.48Å; E63-W66 PolarHBondContact OE1-N 3.33Å; W66-A68 VanDerWaalsContact C-N 3.35Å; W66-A68 PolarHBondContact O-N 2.91Å; W66-Y69 WeakPolarHBondContact O-CB 3.3Å; W66-Y69 PolarHBondContact O-N 2.81Å; W66-M70 HydrophobicContact CD2-CE 4Å; W66-M70 HydrophobicContact CE3-CE 3.92Å; W66-M70 HydrophobicContact CH2-CE 3.61Å; W66-M70 HydrophobicContact CH2-SD 4.26Å; W66-M70 HydrophobicContact CZ2-CE 3.67Å; W66-M70 HydrophobicContact CZ2-CG 4.46Å; W66-M70 HydrophobicContact CZ2-SD 3.78Å; W66-M70 HydrophobicContact CZ3-CE 3.72Å; W66-M70 VanDerWaalsContact O-CG 3.31Å; W66-M70 WeakPolarHBondContact O-CG 3.37Å; W66-M70 PolarHBondContact O-N 3.3Å; W66-F103 HydrophobicContact CE3-CE1 4.27Å; W66-F103 HydrophobicContact CZ3-CD1 4.28Å; W66-F103 AromaticContact CZ3-CE1 3.98Å; W66-F103 HydrophobicContact CZ3-CE1 3.98Å; W66-L106 HydrophobicContact CH2-CB 4.08Å; W66-L106 HydrophobicContact CH2-CD1 4.44Å; W66-L106 HydrophobicContact CZ3-CD1 4.28Å; W66-T110 HydrophobicContact CH2-CG2 4.36Å; W66-T110 HydrophobicContact CZ2-CG2 4.18Å; W66-G113 PolarHBondContact NE1-O 3.2Å; W66-I116 HydrophobicContact CG-CD1 4.25Å; W66-F123 AromaticContact CZ3-CE2 3.89Å; W66-F123 HydrophobicContact CZ3-CE2 3.89Å; W66-L167 HydrophobicContact CB-CD1 4.47Å; W66-L167 HydrophobicContact CD2-CB 4.23Å; W66-L167 HydrophobicContact CD2-CD1 3.7Å; W66-L167 HydrophobicContact CE3-CB 3.58Å; W66-L167 HydrophobicContact CE3-CD1 3.77Å; W66-L167 HydrophobicContact CE3-CG 4.32Å; W66-L167 HydrophobicContact CG-CD1 4.02Å; W66-L167 HydrophobicContact CZ3-CB 4.16Å; W66-L167 HydrophobicContact CZ3-CD1 4.27Å
67	K	94.8	Very high	94.6	Very high	121 Å²	121	47.3 Å²	47.3	53%	0.526	25%	0.246	S	C	.	.	H	α-helix	trans	-58.9	-47.7	175.3	-75.3	-177.6	-179.3	-174.7	0	111.6	E63 D65 Y69 M70 D71	E63-K67 HydrophobicContact CG-CD 4.02Å; E63-K67 HydrophobicContact CG-CG 4.14Å; E63-K67 PolarHBondContact OE1-N 3.46Å; D65-K67 PolarHBondContact O-N 2.7Å; K67-Y69 VanDerWaalsContact C-N 3.26Å; K67-Y69 PolarHBondContact O-N 3.28Å; K67-M70 WeakPolarHBondContact O-CA 3.26Å; K67-M70 WeakPolarHBondContact O-CB 3.43Å; K67-M70 PolarHBondContact O-N 3.39Å; K67-D71 VanDerWaalsContact O-CG 3.25Å; K67-D71 PolarHBondContact O-N 2.75Å
68	A	94.6	Very high	94.6	Very high	1 Å²	1	47.5 Å²	47.5	1%	0.008	25%	0.251	C	S	.	.	H	α-helix	trans	-58.6	-40	177.5	0	0	0	0	0	111.8	D65 W66 M70 D71 E72 T90	D65-A68 PolarHBondContact O-N 3.03Å; W66-A68 VanDerWaalsContact C-N 3.35Å; W66-A68 PolarHBondContact O-N 2.91Å; A68-M70 VanDerWaalsContact C-N 3.33Å; A68-M70 PolarHBondContact O-N 2.93Å; A68-D71 PolarHBondContact O-N 3.01Å; A68-E72 WeakPolarHBondContact O-CB 3.26Å; A68-E72 WeakPolarHBondContact O-CG 3.27Å; A68-E72 PolarHBondContact O-N 2.91Å; A68-T90 HydrophobicContact CB-CG2 4.19Å; A68-T90 WeakPolarHBondContact CB-OG1 3.49Å
69	Y	96.4	Very high	94.7	Very high	1 Å²	1	42.4 Å²	42.4	0%	0.004	24%	0.241	C	C	.	.	H	α-helix	trans	-61.9	-40.3	173.9	-61.4	-21.2	0	0	0	112.3	D65 W66 K67 V73 Y95 F99 F103 F168 N169	D65-Y69 HydrophobicContact CB-CD1 4.16Å; D65-Y69 HydrophobicContact CB-CD2 4.36Å; D65-Y69 HydrophobicContact CB-CE1 3.55Å; D65-Y69 HydrophobicContact CB-CE2 3.82Å; D65-Y69 WeakPolarHBondContact CB-OH 3.39Å; D65-Y69 VanDerWaalsContact O-CD1 3.31Å; D65-Y69 WeakPolarHBondContact O-CD1 3.36Å; D65-Y69 WeakPolarHBondContact O-CD2 3.37Å; D65-Y69 PolarHBondContact O-N 2.9Å; D65-Y69 PolarHBondContact OD2-OH 3.49Å; W66-Y69 WeakPolarHBondContact O-CB 3.3Å; W66-Y69 PolarHBondContact O-N 2.81Å; K67-Y69 VanDerWaalsContact C-N 3.26Å; K67-Y69 PolarHBondContact O-N 3.28Å; Y69-V73 WeakPolarHBondContact O-CG1 3.39Å; Y69-V73 WeakPolarHBondContact O-CG2 3.28Å; Y69-V73 PolarHBondContact O-N 3.11Å; Y69-V73 VanDerWaalsContact O-N 3.12Å; Y69-Y95 HydrophobicContact CD1-CE2 4.09Å; Y69-Y95 HydrophobicContact CE1-CD2 4.43Å; Y69-Y95 AromaticContact CE1-CE2 3.52Å; Y69-Y95 HydrophobicContact CE1-CE2 3.52Å; Y69-Y95 AromaticContact CE1-CZ 3.96Å; Y69-F99 AromaticContact CD1-CE2 3.75Å; Y69-F99 HydrophobicContact CD1-CE2 3.75Å; Y69-F99 AromaticContact CD1-CZ 3.39Å; Y69-F99 HydrophobicContact CD1-CZ 3.39Å; Y69-F99 HydrophobicContact CD2-CE2 4.18Å; Y69-F99 HydrophobicContact CD2-CZ 4.38Å; Y69-F99 HydrophobicContact CE1-CE2 4.06Å; Y69-F99 HydrophobicContact CE1-CZ 4.07Å; Y69-F99 HydrophobicContact CE2-CE2 4.42Å; Y69-F99 AromaticContact CG-CE2 3.82Å; Y69-F99 HydrophobicContact CG-CE2 3.82Å; Y69-F99 AromaticContact CG-CZ 3.58Å; Y69-F99 HydrophobicContact CG-CZ 3.58Å; Y69-F103 AromaticContact CD2-CD1 3.87Å; Y69-F103 HydrophobicContact CD2-CD1 3.87Å; Y69-F103 AromaticContact CD2-CE1 3.34Å; Y69-F103 HydrophobicContact CD2-CE1 3.34Å; Y69-F103 HydrophobicContact CD2-CZ 4.01Å; Y69-F103 AromaticContact CE2-CE1 3.92Å; Y69-F103 HydrophobicContact CE2-CE1 3.92Å; Y69-F103 HydrophobicContact CE2-CZ 4.16Å; Y69-F103 HydrophobicContact CG-CD1 4.14Å; Y69-F103 HydrophobicContact CG-CE1 4.05Å; Y69-F168 WeakPolarHBondContact OH-CD1 3.49Å; Y69-N169 HydrophobicContact CE2-CB 4.36Å; Y69-N169 PolarHBondContact OH-N 3.34Å; Y69-N169 PolarHBondContact OH-OD1 3.23Å
70	M	97.3	Very high	94.8	Very high	9 Å²	9	42.2 Å²	42.2	4%	0.044	24%	0.24	C	C	.	.	H	α-helix	trans	-66.5	-42.2	177.7	-61.2	-60.7	105.6	0	0	111.4	W66 K67 A68 V73 E74 F103 Y107 G113	W66-M70 HydrophobicContact CD2-CE 4Å; W66-M70 HydrophobicContact CE3-CE 3.92Å; W66-M70 HydrophobicContact CH2-CE 3.61Å; W66-M70 HydrophobicContact CH2-SD 4.26Å; W66-M70 HydrophobicContact CZ2-CE 3.67Å; W66-M70 HydrophobicContact CZ2-CG 4.46Å; W66-M70 HydrophobicContact CZ2-SD 3.78Å; W66-M70 HydrophobicContact CZ3-CE 3.72Å; W66-M70 VanDerWaalsContact O-CG 3.31Å; W66-M70 WeakPolarHBondContact O-CG 3.37Å; W66-M70 PolarHBondContact O-N 3.3Å; K67-M70 WeakPolarHBondContact O-CA 3.26Å; K67-M70 WeakPolarHBondContact O-CB 3.43Å; K67-M70 PolarHBondContact O-N 3.39Å; A68-M70 VanDerWaalsContact C-N 3.33Å; A68-M70 PolarHBondContact O-N 2.93Å; M70-V73 WeakPolarHBondContact O-CG2 3.21Å; M70-V73 PolarHBondContact O-N 3.2Å; M70-E74 VanDerWaalsContact O-CB 3.22Å; M70-E74 WeakPolarHBondContact O-CB 3.41Å; M70-E74 PolarHBondContact O-N 3.29Å; M70-F103 HydrophobicContact CE-CD1 3.86Å; M70-Y107 HydrophobicContact CB-CD2 4.08Å; M70-Y107 HydrophobicContact CB-CE2 4.49Å; M70-Y107 HydrophobicContact CG-CD2 4.47Å; M70-Y107 HydrophobicContact SD-CD2 3.84Å; M70-Y107 HydrophobicContact SD-CG 4.33Å; M70-G113 VanDerWaalsContact SD-CA 3.56Å
71	D	95.5	Very high	94.9	Very high	58 Å²	58	43.1 Å²	43.1	31%	0.31	23%	0.227	S	C	.	.	H	α-helix	trans	-64.4	-43.9	177.1	-57.5	-28.1	0	0	0	111.3	K67 A68 V73 E74 G75	K67-D71 VanDerWaalsContact O-CG 3.25Å; K67-D71 PolarHBondContact O-N 2.75Å; A68-D71 PolarHBondContact O-N 3.01Å; D71-V73 PolarHBondContact O-N 3.12Å; D71-E74 PolarHBondContact O-N 3.43Å; D71-G75 PolarHBondContact O-N 2.97Å
72	E	95.4	Very high	95.1	Very high	4 Å²	4	41.5 Å²	41.5	2%	0.019	22%	0.222	C	C	.	.	H	α-helix	trans	-59.6	-45	177.8	-74.9	169.2	171.5	0	0	111.8	A68 L93 F99	A68-E72 WeakPolarHBondContact O-CB 3.26Å; A68-E72 WeakPolarHBondContact O-CG 3.27Å; A68-E72 PolarHBondContact O-N 2.91Å; E72-L93 HydrophobicContact CB-CB 4.46Å; E72-L93 HydrophobicContact CB-CD1 4.42Å; E72-L93 HydrophobicContact CG-CB 4.05Å; E72-L93 HydrophobicContact CG-CD1 4.48Å; E72-L93 WeakPolarHBondContact OE1-CA 3.47Å; E72-L93 PolarHBondContact OE1-N 3.07Å; E72-L93 WeakPolarHBondContact OE2-CD1 3.34Å; E72-F99 WeakPolarHBondContact OE2-CE1 3.42Å
73	V	96.8	Very high	95.2	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-76.6	-31.2	178.3	-58.9	0	0	0	0	112.8	Y69 M70 D71 G75 V76 I77 F99 V100 F103 Y107	Y69-V73 WeakPolarHBondContact O-CG1 3.39Å; Y69-V73 WeakPolarHBondContact O-CG2 3.28Å; Y69-V73 PolarHBondContact O-N 3.11Å; Y69-V73 VanDerWaalsContact O-N 3.12Å; M70-V73 WeakPolarHBondContact O-CG2 3.21Å; M70-V73 PolarHBondContact O-N 3.2Å; D71-V73 PolarHBondContact O-N 3.12Å; V73-G75 VanDerWaalsContact C-N 3.3Å; V73-G75 PolarHBondContact O-N 3.01Å; V73-V76 PolarHBondContact O-N 3.39Å; V73-V76 VanDerWaalsContact O-N 3.14Å; V73-I77 WeakPolarHBondContact O-CG1 3.3Å; V73-I77 PolarHBondContact O-N 3.32Å; V73-F99 HydrophobicContact CG1-CE1 4.37Å; V73-V100 HydrophobicContact CG1-CG1 4.42Å; V73-F103 HydrophobicContact CG1-CB 3.7Å; V73-Y107 HydrophobicContact CG2-CD2 4.02Å; V73-Y107 HydrophobicContact CG2-CG 4.16Å
74	E	96.6	Very high	95.3	Very high	64 Å²	64	38.8 Å²	38.8	30%	0.299	21%	0.21	S	C	.	.	H	α-helix	trans	-61.9	-38.7	173.7	-179	166.2	-127.5	0	0	111.4	M70 D71 V76 I77 N78 Y107	M70-E74 VanDerWaalsContact O-CB 3.22Å; M70-E74 WeakPolarHBondContact O-CB 3.41Å; M70-E74 PolarHBondContact O-N 3.29Å; D71-E74 PolarHBondContact O-N 3.43Å; E74-V76 VanDerWaalsContact C-N 3.28Å; E74-V76 PolarHBondContact O-N 3.35Å; E74-I77 PolarHBondContact O-N 3.28Å; E74-N78 WeakPolarHBondContact O-CB 3.49Å; E74-N78 VanDerWaalsContact O-CG 3.28Å; E74-N78 PolarHBondContact O-N 3.46Å; E74-N78 PolarHBondContact O-ND2 2.88Å; E74-Y107 HydrophobicContact CB-CE2 4Å; E74-Y107 HydrophobicContact CG-CE2 4.48Å; E74-Y107 PolarHBondContact OE1-OH 3.31Å
75	G	95.6	Very high	95.5	Very high	17 Å²	17	41.7 Å²	41.7	18%	0.175	22%	0.222	C	C	.	.	H	α-helix	trans	-54.3	-43.4	171.5	0	0	0	0	0	112.8	D71 V73 N78 G79 T80	D71-G75 PolarHBondContact O-N 2.97Å; V73-G75 VanDerWaalsContact C-N 3.3Å; V73-G75 PolarHBondContact O-N 3.01Å; G75-N78 PolarHBondContact O-N 3.32Å; G75-G79 PolarHBondContact O-N 2.88Å; G75-T80 WeakPolarHBondContact O-CB 3.36Å; G75-T80 PolarHBondContact O-N 2.94Å; G75-T80 PolarHBondContact O-OG1 3.01Å
76	V	96.4	Very high	95.6	Very high	12 Å²	12	41.1 Å²	41.1	7%	0.073	22%	0.219	C	C	.	.	H	α-helix	trans	-69	-42.2	176.8	-178.5	0	0	0	0	111.7	V73 E74 N78 G79 T80 Y81 L86 V100 F244	V73-V76 PolarHBondContact O-N 3.39Å; V73-V76 VanDerWaalsContact O-N 3.14Å; E74-V76 VanDerWaalsContact C-N 3.28Å; E74-V76 PolarHBondContact O-N 3.35Å; V76-N78 PolarHBondContact O-N 3.47Å; V76-G79 PolarHBondContact O-N 2.9Å; V76-T80 WeakPolarHBondContact CA-O 3.11Å; V76-Y81 HydrophobicContact CG1-CD1 4.29Å; V76-Y81 HydrophobicContact CG1-CE1 3.97Å; V76-L86 HydrophobicContact CG2-CD1 3.48Å; V76-L86 VanDerWaalsContact CG2-CD1 3.48Å; V76-L86 HydrophobicContact CG2-CD2 3.79Å; V76-L86 HydrophobicContact CG2-CG 4.3Å; V76-V100 HydrophobicContact CB-CG1 4.06Å; V76-V100 HydrophobicContact CG1-CG1 3.97Å; V76-V100 HydrophobicContact CG2-CG1 3.85Å; V76-F244 HydrophobicContact CG1-CE1 3.96Å; V76-F244 HydrophobicContact CG1-CZ 4.07Å; V76-F244 HydrophobicContact CG2-CE1 4.05Å; V76-F244 HydrophobicContact CG2-CZ 4.44Å
77	I	96.6	Very high	95.4	Very high	54 Å²	54	48.2 Å²	48.2	28%	0.277	25%	0.25	S	C	.	.	H	α-helix	trans	-59	-35.3	176.2	-68.3	165.2	0	0	0	110.8	V73 E74 G79 T104 Y107 Y108	V73-I77 WeakPolarHBondContact O-CG1 3.3Å; V73-I77 PolarHBondContact O-N 3.32Å; E74-I77 PolarHBondContact O-N 3.28Å; I77-G79 PolarHBondContact O-N 2.98Å; I77-T104 HydrophobicContact CD1-CG2 4.04Å; I77-T104 HydrophobicContact CG1-CG2 4.09Å; I77-Y107 HydrophobicContact CD1-CD1 3.63Å; I77-Y107 HydrophobicContact CD1-CE1 3.75Å; I77-Y107 HydrophobicContact CD1-CG 4.18Å; I77-Y108 HydrophobicContact CD1-CE2 4.1Å; I77-Y108 VanDerWaalsContact CG2-OH 3.3Å; I77-Y108 WeakPolarHBondContact CG2-OH 3.41Å
78	N	96.1	Very high	95.1	Very high	120 Å²	120	43.1 Å²	43.1	64%	0.642	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	-80.8	5.1	177.4	-67.4	-27.6	0	0	0	114	E74 G75 V76	E74-N78 WeakPolarHBondContact O-CB 3.49Å; E74-N78 VanDerWaalsContact O-CG 3.28Å; E74-N78 PolarHBondContact O-N 3.46Å; E74-N78 PolarHBondContact O-ND2 2.88Å; G75-N78 PolarHBondContact O-N 3.32Å; V76-N78 PolarHBondContact O-N 3.47Å
79	G	95.5	Very high	94.4	Very high	43 Å²	43	49.7 Å²	49.7	44%	0.443	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	96.1	9	174.7	0	0	0	0	0	115.4	G75 V76 I77 Y81	G75-G79 PolarHBondContact O-N 2.88Å; V76-G79 PolarHBondContact O-N 2.9Å; I77-G79 PolarHBondContact O-N 2.98Å; G79-Y81 WeakPolarHBondContact O-CD2 3.47Å; G79-Y81 PolarHBondContact O-N 3.34Å
80	T	96.3	Very high	93.6	Very high	40 Å²	40	53 Å²	53	25%	0.245	29%	0.287	C	S	.	.			trans	-84.3	104.4	176.8	-48	0	0	0	0	110.1	G75 V76 E85 L86	G75-T80 WeakPolarHBondContact O-CB 3.36Å; G75-T80 PolarHBondContact O-N 2.94Å; G75-T80 PolarHBondContact O-OG1 3.01Å; V76-T80 WeakPolarHBondContact CA-O 3.11Å; T80-E85 HydrophobicContact CG2-CB 3.87Å; T80-L86 HydrophobicContact CG2-CD2 3.91Å; T80-L86 HydrophobicContact CG2-CG 4.34Å
81	Y	95.7	Very high	93.1	Very high	98 Å²	98	53.6 Å²	53.6	38%	0.384	30%	0.296	S	S	.	.			trans	-102	1	177.1	-62.6	-76.5	0	0	0	113.4	V76 G79 Y83 P243 F244	V76-Y81 HydrophobicContact CG1-CD1 4.29Å; V76-Y81 HydrophobicContact CG1-CE1 3.97Å; G79-Y81 WeakPolarHBondContact O-CD2 3.47Å; G79-Y81 PolarHBondContact O-N 3.34Å; Y81-Y83 PolarHBondContact O-N 3.15Å; Y81-P243 HydrophobicContact CD1-CB 3.78Å; Y81-P243 HydrophobicContact CE1-CB 3.98Å; Y81-F244 AromaticContact CD1-CD1 3.9Å; Y81-F244 HydrophobicContact CD1-CD1 3.9Å; Y81-F244 AromaticContact CD1-CE1 3.66Å; Y81-F244 HydrophobicContact CD1-CE1 3.66Å; Y81-F244 HydrophobicContact CD1-CZ 4.44Å; Y81-F244 HydrophobicContact CE1-CE1 4.42Å; Y81-F244 WeakPolarHBondContact O-CD1 3.33Å
82	D	96.2	Very high	92.9	Very high	24 Å²	24	52.8 Å²	52.8	13%	0.128	29%	0.293	C	S	.	.			trans	-84.7	109.8	171.7	-162.2	-35.8	0	0	0	111	T84 E85 L86 N247 N248	D82-T84 PolarHBondContact O-N 2.92Å; D82-T84 VanDerWaalsContact O-N 3.09Å; D82-T84 WeakPolarHBondContact OD1-CB 3.32Å; D82-T84 WeakPolarHBondContact OD1-CG2 3.42Å; D82-T84 PolarHBondContact OD1-N 3.43Å; D82-T84 PolarHBondContact OD1-OG1 3.44Å; D82-E85 HydrophobicContact CB-CB 4.48Å; D82-E85 HydrophobicContact CB-CG 4.1Å; D82-E85 PolarHBondContact O-N 3.29Å; D82-L86 PolarHBondContact O-N 3.44Å; D82-N247 WeakPolarHBondContact CB-ND2 3.45Å; D82-N247 PolarHBondContact N-ND2 2.68Å; D82-N248 VanDerWaalsContact CG-ND2 3.32Å; D82-N248 PolarHBondContact OD1-ND2 3.28Å; D82-N248 VanDerWaalsContact OD1-ND2 3.09Å; D82-N248 WeakPolarHBondContact OD2-CB 3.32Å; D82-N248 PolarHBondContact OD2-ND2 3.38Å
83	Y	94.4	Very high	92.8	Very high	1 Å²	1	52.6 Å²	52.6	0%	0.004	29%	0.292	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-19.5	177	-95.8	-130	0	0	0	114.2	Y81 E85 L86 L93 Y95 A97 V100 F244 Y252 R255 A256	Y81-Y83 PolarHBondContact O-N 3.15Å; Y83-E85 VanDerWaalsContact C-N 3.26Å; Y83-L86 HydrophobicContact CD2-CD1 3.79Å; Y83-L86 HydrophobicContact CE2-CD1 4.02Å; Y83-L86 HydrophobicContact CG-CD1 4.45Å; Y83-L93 HydrophobicContact CD1-CD2 4.18Å; Y83-L93 HydrophobicContact CD1-CG 4.35Å; Y83-L93 HydrophobicContact CD2-CD2 4.44Å; Y83-L93 HydrophobicContact CE1-CD2 3.8Å; Y83-L93 HydrophobicContact CE1-CG 4.09Å; Y83-L93 HydrophobicContact CE2-CD2 4.01Å; Y83-Y95 VanDerWaalsContact CE1-O 3.31Å; Y83-Y95 WeakPolarHBondContact CE1-O 3.47Å; Y83-A97 WeakPolarHBondContact OH-CA 3.4Å; Y83-A97 PolarHBondContact OH-N 3.29Å; Y83-V100 WeakPolarHBondContact OH-CG2 3.21Å; Y83-F244 HydrophobicContact CD2-CB 3.95Å; Y83-F244 AromaticContact CD2-CD1 3.63Å; Y83-F244 HydrophobicContact CD2-CD1 3.63Å; Y83-F244 HydrophobicContact CD2-CE1 4.26Å; Y83-F244 AromaticContact CD2-CG 3.81Å; Y83-F244 HydrophobicContact CD2-CG 3.81Å; Y83-F244 HydrophobicContact CE2-CB 3.87Å; Y83-F244 AromaticContact CE2-CD1 3.26Å; Y83-F244 HydrophobicContact CE2-CD1 3.26Å; Y83-F244 AromaticContact CE2-CD2 3.72Å; Y83-F244 HydrophobicContact CE2-CD2 3.72Å; Y83-F244 AromaticContact CE2-CE1 3.58Å; Y83-F244 HydrophobicContact CE2-CE1 3.58Å; Y83-F244 HydrophobicContact CE2-CE2 4.03Å; Y83-F244 AromaticContact CE2-CG 3.31Å; Y83-F244 HydrophobicContact CE2-CG 3.31Å; Y83-F244 AromaticContact CE2-CZ 3.96Å; Y83-F244 HydrophobicContact CE2-CZ 3.96Å; Y83-Y252 AromaticContact CD1-CD2 3.81Å; Y83-Y252 HydrophobicContact CD1-CD2 3.81Å; Y83-Y252 HydrophobicContact CD1-CE2 4.34Å; Y83-Y252 AromaticContact CD2-CD2 3.77Å; Y83-Y252 HydrophobicContact CD2-CD2 3.77Å; Y83-Y252 HydrophobicContact CD2-CE2 4.46Å; Y83-Y252 AromaticContact CE1-CD2 3.62Å; Y83-Y252 HydrophobicContact CE1-CD2 3.62Å; Y83-Y252 AromaticContact CE1-CE2 3.68Å; Y83-Y252 HydrophobicContact CE1-CE2 3.68Å; Y83-Y252 AromaticContact CE2-CD2 3.64Å; Y83-Y252 HydrophobicContact CE2-CD2 3.64Å; Y83-Y252 AromaticContact CE2-CE2 3.88Å; Y83-Y252 HydrophobicContact CE2-CE2 3.88Å; Y83-Y252 AromaticContact CG-CD2 3.87Å; Y83-Y252 HydrophobicContact CG-CD2 3.87Å; Y83-Y252 AromaticContact CZ-CD2 3.54Å; Y83-Y252 AromaticContact CZ-CE2 3.42Å; Y83-Y252 VanDerWaalsContact CZ-CE2 3.42Å; Y83-R255 HydrophobicContact CD1-CB 4.01Å; Y83-A256 HydrophobicContact CD1-CB 4.22Å; Y83-A256 HydrophobicContact CE1-CB 3.87Å
84	T	94	Very high	92.6	Very high	63 Å²	63	52.8 Å²	52.8	39%	0.387	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.3	-18.9	176.6	67.6	0	0	0	0	113	D82	D82-T84 PolarHBondContact O-N 2.92Å; D82-T84 VanDerWaalsContact O-N 3.09Å; D82-T84 WeakPolarHBondContact OD1-CB 3.32Å; D82-T84 WeakPolarHBondContact OD1-CG2 3.42Å; D82-T84 PolarHBondContact OD1-N 3.43Å; D82-T84 PolarHBondContact OD1-OG1 3.44Å
85	E	94.3	Very high	92.5	Very high	128 Å²	128	50.7 Å²	50.7	60%	0.598	28%	0.283	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.5	-23.4	179.6	-59.6	-175.3	167.5	0	0	112.6	T80 D82 Y83 K87	T80-E85 HydrophobicContact CG2-CB 3.87Å; D82-E85 HydrophobicContact CB-CB 4.48Å; D82-E85 HydrophobicContact CB-CG 4.1Å; D82-E85 PolarHBondContact O-N 3.29Å; Y83-E85 VanDerWaalsContact C-N 3.26Å; E85-K87 PolarHBondContact O-N 3.26Å
86	L	93.7	Very high	92.5	Very high	4 Å²	4	49.9 Å²	49.9	2%	0.021	28%	0.275	C	S	.	.			trans	-71.7	115.8	178.3	-63.4	174.4	0	0	0	111.4	V76 T80 D82 Y83 L93	V76-L86 HydrophobicContact CG2-CD1 3.48Å; V76-L86 VanDerWaalsContact CG2-CD1 3.48Å; V76-L86 HydrophobicContact CG2-CD2 3.79Å; V76-L86 HydrophobicContact CG2-CG 4.3Å; T80-L86 HydrophobicContact CG2-CD2 3.91Å; T80-L86 HydrophobicContact CG2-CG 4.34Å; D82-L86 PolarHBondContact O-N 3.44Å; Y83-L86 HydrophobicContact CD2-CD1 3.79Å; Y83-L86 HydrophobicContact CE2-CD1 4.02Å; Y83-L86 HydrophobicContact CG-CD1 4.45Å; L86-L93 HydrophobicContact CB-CB 3.85Å; L86-L93 HydrophobicContact CB-CD2 4.07Å; L86-L93 HydrophobicContact CD1-CD2 3.64Å; L86-L93 HydrophobicContact CG-CD2 4.5Å; L86-L93 PolarHBondContact O-N 2.95Å
87	K	92.5	Very high	92.6	Very high	151 Å²	151	49.3 Å²	49.3	66%	0.657	27%	0.272	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-154.9	150	179.4	64.3	-175.4	-180	-178.3	0	111	E85 G91	E85-K87 PolarHBondContact O-N 3.26Å; K87-G91 CarbonylContact C-O 3.57Å; K87-G91 WeakPolarHBondContact CA-O 3.34Å; K87-G91 WeakPolarHBondContact CB-O 3.18Å
88	G	87.4	Confident	92.6	Very high	14 Å²	14	47 Å²	47	14%	0.144	26%	0.26	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117	-171.6	166.7	0	0	0	0	0	111.7	T90 G91	G88-T90 PolarHBondContact O-N 2.92Å; G88-T90 VanDerWaalsContact O-N 3.13Å; G88-G91 PolarHBondContact N-O 3.19Å; G88-G91 PolarHBondContact O-N 2.85Å; G88-G91 VanDerWaalsContact O-N 3.07Å
89	D	79.6	Confident	92.7	Very high	139 Å²	139	41.2 Å²	41.2	74%	0.743	23%	0.23	S	C	*	.	T	Hydrogen-bonded Turn	trans	-56.9	-28.7	-179.1	-77.6	-16.6	0	0	0	114.2
90	T	80.3	Confident	92.8	Very high	69 Å²	69	39.2 Å²	39.2	42%	0.423	21%	0.209	S	C	.	.	T	Hydrogen-bonded Turn	trans	-94.7	1.4	-179.2	63.6	0	0	0	0	114.7	I64 D65 A68 G88	I64-T90 WeakPolarHBondContact O-CG2 3.33Å; D65-T90 PolarHBondContact OD1-OG1 3.12Å; D65-T90 VanDerWaalsContact OD1-OG1 3.06Å; A68-T90 HydrophobicContact CB-CG2 4.19Å; A68-T90 WeakPolarHBondContact CB-OG1 3.49Å; G88-T90 PolarHBondContact O-N 2.92Å; G88-T90 VanDerWaalsContact O-N 3.13Å
91	G	86.8	Confident	92.9	Very high	23 Å²	23	41.4 Å²	41.4	24%	0.237	21%	0.213	C	C	.	.	E	Extended strand (participates in β ladder)	trans	132.1	-167.5	174.2	0	0	0	0	0	114	K87 G88	K87-G91 CarbonylContact C-O 3.57Å; K87-G91 WeakPolarHBondContact CA-O 3.34Å; K87-G91 WeakPolarHBondContact CB-O 3.18Å; G88-G91 PolarHBondContact N-O 3.19Å; G88-G91 PolarHBondContact O-N 2.85Å; G88-G91 VanDerWaalsContact O-N 3.07Å
92	P	90.4	Very high	93	Very high	40 Å²	40	39.2 Å²	39.2	26%	0.26	21%	0.207	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-72	154.8	-179.9	30.6	-34.6	0	0	0	112	V94	P92-V94 HydrophobicContact CG-CG1 4.25Å; P92-V94 PolarHBondContact O-N 3.41Å
93	L	93	Very high	93.1	Very high	0 Å²	0	38 Å²	38	0%	0	20%	0.201	C	C	.	.			trans	-62.4	118.2	168.7	175.8	60.4	0	0	0	109.6	E72 Y83 L86 Y95 F99 V100	E72-L93 HydrophobicContact CB-CB 4.46Å; E72-L93 HydrophobicContact CB-CD1 4.42Å; E72-L93 HydrophobicContact CG-CB 4.05Å; E72-L93 HydrophobicContact CG-CD1 4.48Å; E72-L93 WeakPolarHBondContact OE1-CA 3.47Å; E72-L93 PolarHBondContact OE1-N 3.07Å; E72-L93 WeakPolarHBondContact OE2-CD1 3.34Å; Y83-L93 HydrophobicContact CD1-CD2 4.18Å; Y83-L93 HydrophobicContact CD1-CG 4.35Å; Y83-L93 HydrophobicContact CD2-CD2 4.44Å; Y83-L93 HydrophobicContact CE1-CD2 3.8Å; Y83-L93 HydrophobicContact CE1-CG 4.09Å; Y83-L93 HydrophobicContact CE2-CD2 4.01Å; L86-L93 HydrophobicContact CB-CB 3.85Å; L86-L93 HydrophobicContact CB-CD2 4.07Å; L86-L93 HydrophobicContact CD1-CD2 3.64Å; L86-L93 HydrophobicContact CG-CD2 4.5Å; L86-L93 PolarHBondContact O-N 2.95Å; L93-Y95 HydrophobicContact CD1-CD2 3.76Å; L93-Y95 HydrophobicContact CD1-CG 4.36Å; L93-F99 HydrophobicContact CD1-CD1 3.64Å; L93-F99 HydrophobicContact CD1-CE1 3.56Å; L93-V100 HydrophobicContact CD2-CG2 3.78Å
94	V	92.4	Very high	93.3	Very high	5 Å²	5	39.3 Å²	39.3	3%	0.03	21%	0.209	C	C	.	.			trans	-124.7	20.3	-178.7	-67.4	0	0	0	0	112.8	P92 R255	P92-V94 HydrophobicContact CG-CG1 4.25Å; P92-V94 PolarHBondContact O-N 3.41Å; V94-R255 CarbonylContact C-O 3.25Å; V94-R255 VanDerWaalsContact CA-O 3.3Å; V94-R255 WeakPolarHBondContact CA-O 3.42Å
95	Y	95.1	Very high	93.5	Very high	20 Å²	20	38.7 Å²	38.7	8%	0.078	21%	0.21	C	C	.	.	S	Bend	trans	-113.7	143.7	-177.5	-49.9	-60.9	0	0	0	109.2	Y69 Y83 L93 F99 N169	Y69-Y95 HydrophobicContact CD1-CE2 4.09Å; Y69-Y95 HydrophobicContact CE1-CD2 4.43Å; Y69-Y95 AromaticContact CE1-CE2 3.52Å; Y69-Y95 HydrophobicContact CE1-CE2 3.52Å; Y69-Y95 AromaticContact CE1-CZ 3.96Å; Y83-Y95 VanDerWaalsContact CE1-O 3.31Å; Y83-Y95 WeakPolarHBondContact CE1-O 3.47Å; L93-Y95 HydrophobicContact CD1-CD2 3.76Å; L93-Y95 HydrophobicContact CD1-CG 4.36Å; Y95-F99 AromaticContact CD2-CD1 3.85Å; Y95-F99 HydrophobicContact CD2-CD1 3.85Å; Y95-F99 HydrophobicContact CD2-CD2 4.05Å; Y95-F99 AromaticContact CD2-CE1 3.78Å; Y95-F99 HydrophobicContact CD2-CE1 3.78Å; Y95-F99 AromaticContact CD2-CE2 3.97Å; Y95-F99 HydrophobicContact CD2-CE2 3.97Å; Y95-F99 AromaticContact CD2-CG 3.98Å; Y95-F99 HydrophobicContact CD2-CG 3.98Å; Y95-F99 AromaticContact CD2-CZ 3.83Å; Y95-F99 HydrophobicContact CD2-CZ 3.83Å; Y95-F99 HydrophobicContact CE2-CE2 4.4Å; Y95-F99 HydrophobicContact CE2-CZ 4.28Å; Y95-F99 HydrophobicContact CG-CB 4.46Å; Y95-F99 HydrophobicContact CG-CD1 4.23Å; Y95-F99 HydrophobicContact CG-CD2 4.27Å; Y95-F99 HydrophobicContact CG-CG 4.06Å; Y95-N169 WeakPolarHBondContact CD1-ND2 3.31Å; Y95-N169 VanDerWaalsContact CE1-ND2 3.29Å; Y95-N169 WeakPolarHBondContact CE1-ND2 3.19Å; Y95-N169 VanDerWaalsContact CG-ND2 3.27Å
96	P	96.4	Very high	93.7	Very high	0 Å²	0	33 Å²	33	0%	0	18%	0.184	C	C	.	.			trans	-68.6	172.9	179.4	-11.7	26.1	0	0	0	112.6	G98 F99 S201 A256 F257	P96-G98 PolarHBondContact O-N 2.98Å; P96-F99 WeakPolarHBondContact O-CB 3.4Å; P96-F99 PolarHBondContact O-N 3.24Å; P96-S201 CarbonylContact C-O 3.58Å; P96-S201 VanDerWaalsContact CB-O 3.31Å; P96-S201 WeakPolarHBondContact CB-O 3.48Å; P96-A256 HydrophobicContact CB-CB 4.2Å; P96-A256 HydrophobicContact CG-CB 4.47Å; P96-A256 WeakPolarHBondContact CG-O 3.29Å; P96-F257 HydrophobicContact CB-CE1 4.41Å; P96-F257 HydrophobicContact CB-CE2 4.16Å; P96-F257 HydrophobicContact CB-CZ 3.86Å; P96-F257 HydrophobicContact CG-CD1 4.29Å; P96-F257 HydrophobicContact CG-CE1 3.74Å; P96-F257 HydrophobicContact CG-CE2 4.22Å; P96-F257 HydrophobicContact CG-CZ 3.7Å
97	A	97.1	Very high	93.9	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-60.2	-25.1	-167.5	0	0	0	0	0	115.2	Y83 F99 V100 Y101 L240 F244 Y252	Y83-A97 WeakPolarHBondContact OH-CA 3.4Å; Y83-A97 PolarHBondContact OH-N 3.29Å; A97-F99 VanDerWaalsContact C-N 3.25Å; A97-F99 PolarHBondContact O-N 3.49Å; A97-V100 WeakPolarHBondContact O-CB 3.24Å; A97-V100 PolarHBondContact O-N 3.48Å; A97-V100 VanDerWaalsContact O-N 3.13Å; A97-Y101 HydrophobicContact CB-CE2 3.92Å; A97-Y101 WeakPolarHBondContact O-CD2 3.25Å; A97-Y101 WeakPolarHBondContact O-CE2 2.96Å; A97-Y101 PolarHBondContact O-N 3.08Å; A97-L240 HydrophobicContact CB-CB 4.14Å; A97-L240 WeakPolarHBondContact CB-O 3.26Å; A97-F244 HydrophobicContact CB-CD2 3.87Å; A97-F244 HydrophobicContact CB-CE2 3.62Å; A97-Y252 HydrophobicContact CB-CE2 4.1Å; A97-Y252 WeakPolarHBondContact CB-OH 3.47Å; A97-Y252 PolarHBondContact N-OH 3.04Å
98	G	97.8	Very high	94.1	Very high	4 Å²	4	32.5 Å²	32.5	4%	0.041	18%	0.179	C	C	.	.	H	α-helix	trans	-61.7	-34.5	175.7	0	0	0	0	0	112.9	P96 I102 S201	P96-G98 PolarHBondContact O-N 2.98Å; G98-I102 PolarHBondContact O-N 3.5Å; G98-I102 VanDerWaalsContact O-N 3.15Å; G98-S201 CarbonylContact C-O 3.57Å; G98-S201 WeakPolarHBondContact CA-O 3.35Å; G98-S201 WeakPolarHBondContact CA-OG 3.26Å; G98-S201 PolarHBondContact N-O 3.36Å
99	F	98.1	Very high	94.7	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-58.8	-50.2	171.2	164.4	-94	0	0	0	110.7	Y69 E72 V73 L93 Y95 P96 A97 Y101 I102 F103 N169 S201	Y69-F99 AromaticContact CD1-CE2 3.75Å; Y69-F99 HydrophobicContact CD1-CE2 3.75Å; Y69-F99 AromaticContact CD1-CZ 3.39Å; Y69-F99 HydrophobicContact CD1-CZ 3.39Å; Y69-F99 HydrophobicContact CD2-CE2 4.18Å; Y69-F99 HydrophobicContact CD2-CZ 4.38Å; Y69-F99 HydrophobicContact CE1-CE2 4.06Å; Y69-F99 HydrophobicContact CE1-CZ 4.07Å; Y69-F99 HydrophobicContact CE2-CE2 4.42Å; Y69-F99 AromaticContact CG-CE2 3.82Å; Y69-F99 HydrophobicContact CG-CE2 3.82Å; Y69-F99 AromaticContact CG-CZ 3.58Å; Y69-F99 HydrophobicContact CG-CZ 3.58Å; E72-F99 WeakPolarHBondContact OE2-CE1 3.42Å; V73-F99 HydrophobicContact CG1-CE1 4.37Å; L93-F99 HydrophobicContact CD1-CD1 3.64Å; L93-F99 HydrophobicContact CD1-CE1 3.56Å; Y95-F99 AromaticContact CD2-CD1 3.85Å; Y95-F99 HydrophobicContact CD2-CD1 3.85Å; Y95-F99 HydrophobicContact CD2-CD2 4.05Å; Y95-F99 AromaticContact CD2-CE1 3.78Å; Y95-F99 HydrophobicContact CD2-CE1 3.78Å; Y95-F99 AromaticContact CD2-CE2 3.97Å; Y95-F99 HydrophobicContact CD2-CE2 3.97Å; Y95-F99 AromaticContact CD2-CG 3.98Å; Y95-F99 HydrophobicContact CD2-CG 3.98Å; Y95-F99 AromaticContact CD2-CZ 3.83Å; Y95-F99 HydrophobicContact CD2-CZ 3.83Å; Y95-F99 HydrophobicContact CE2-CE2 4.4Å; Y95-F99 HydrophobicContact CE2-CZ 4.28Å; Y95-F99 HydrophobicContact CG-CB 4.46Å; Y95-F99 HydrophobicContact CG-CD1 4.23Å; Y95-F99 HydrophobicContact CG-CD2 4.27Å; Y95-F99 HydrophobicContact CG-CG 4.06Å; P96-F99 WeakPolarHBondContact O-CB 3.4Å; P96-F99 PolarHBondContact O-N 3.24Å; A97-F99 VanDerWaalsContact C-N 3.25Å; A97-F99 PolarHBondContact O-N 3.49Å; F99-Y101 VanDerWaalsContact C-N 3.34Å; F99-Y101 PolarHBondContact O-N 3.42Å; F99-I102 PolarHBondContact O-N 3.45Å; F99-F103 AromaticContact CD2-CD2 3.28Å; F99-F103 HydrophobicContact CD2-CD2 3.28Å; F99-F103 AromaticContact CD2-CE2 3.48Å; F99-F103 HydrophobicContact CD2-CE2 3.48Å; F99-F103 VanDerWaalsContact CD2-CE2 3.48Å; F99-F103 AromaticContact CD2-CG 3.93Å; F99-F103 HydrophobicContact CD2-CG 3.93Å; F99-F103 HydrophobicContact CD2-CZ 4.26Å; F99-F103 HydrophobicContact CE2-CB 4.24Å; F99-F103 AromaticContact CE2-CD1 3.88Å; F99-F103 HydrophobicContact CE2-CD1 3.88Å; F99-F103 AromaticContact CE2-CD2 3.32Å; F99-F103 HydrophobicContact CE2-CD2 3.32Å; F99-F103 HydrophobicContact CE2-CE1 4.05Å; F99-F103 AromaticContact CE2-CE2 3.5Å; F99-F103 HydrophobicContact CE2-CE2 3.5Å; F99-F103 AromaticContact CE2-CG 3.52Å; F99-F103 HydrophobicContact CE2-CG 3.52Å; F99-F103 AromaticContact CE2-CZ 3.86Å; F99-F103 HydrophobicContact CE2-CZ 3.86Å; F99-F103 HydrophobicContact CG-CD2 4.11Å; F99-F103 HydrophobicContact CZ-CB 4.24Å; F99-F103 HydrophobicContact CZ-CD1 4.26Å; F99-F103 HydrophobicContact CZ-CD2 4.16Å; F99-F103 AromaticContact CZ-CG 3.95Å; F99-F103 HydrophobicContact CZ-CG 3.95Å; F99-F103 WeakPolarHBondContact O-CB 3.47Å; F99-F103 WeakPolarHBondContact O-CD2 3.35Å; F99-F103 PolarHBondContact O-N 2.94Å; F99-N169 HydrophobicContact CD2-CB 3.64Å; F99-N169 WeakPolarHBondContact CD2-ND2 3.18Å; F99-N169 HydrophobicContact CE2-CB 3.79Å; F99-S201 PolarHBondContact N-O 3Å; F99-S201 VanDerWaalsContact N-O 3.12Å
100	V	97.9	Very high	95.5	Very high	1 Å²	1	29.8 Å²	29.8	1%	0.006	16%	0.16	C	C	.	.	H	α-helix	trans	-54.9	-50.8	-178.8	177.5	0	0	0	0	110.4	V73 V76 Y83 L93 A97 I102 F103 T104 F244	V73-V100 HydrophobicContact CG1-CG1 4.42Å; V76-V100 HydrophobicContact CB-CG1 4.06Å; V76-V100 HydrophobicContact CG1-CG1 3.97Å; V76-V100 HydrophobicContact CG2-CG1 3.85Å; Y83-V100 WeakPolarHBondContact OH-CG2 3.21Å; L93-V100 HydrophobicContact CD2-CG2 3.78Å; A97-V100 WeakPolarHBondContact O-CB 3.24Å; A97-V100 PolarHBondContact O-N 3.48Å; A97-V100 VanDerWaalsContact O-N 3.13Å; V100-I102 PolarHBondContact O-N 3.46Å; V100-F103 PolarHBondContact O-N 3.48Å; V100-T104 VanDerWaalsContact O-CB 3.28Å; V100-T104 WeakPolarHBondContact O-CB 3.28Å; V100-T104 PolarHBondContact O-N 3.04Å; V100-T104 PolarHBondContact O-OG1 2.78Å; V100-F244 HydrophobicContact CB-CZ 4.46Å; V100-F244 HydrophobicContact CG1-CZ 4.15Å; V100-F244 HydrophobicContact CG2-CZ 4.43Å
101	Y	98.1	Very high	96.4	Very high	86 Å²	86	30.1 Å²	30.1	34%	0.337	17%	0.165	S	C	.	.	H	α-helix	trans	-64.8	-41.8	-177.3	-58.6	-56.2	0	0	0	113.6	A97 F99 A105 L240	A97-Y101 HydrophobicContact CB-CE2 3.92Å; A97-Y101 WeakPolarHBondContact O-CD2 3.25Å; A97-Y101 WeakPolarHBondContact O-CE2 2.96Å; A97-Y101 PolarHBondContact O-N 3.08Å; F99-Y101 VanDerWaalsContact C-N 3.34Å; F99-Y101 PolarHBondContact O-N 3.42Å; Y101-A105 PolarHBondContact O-N 3.39Å; Y101-L240 HydrophobicContact CD2-CD2 3.87Å; Y101-L240 HydrophobicContact CE2-CB 3.97Å; Y101-L240 HydrophobicContact CE2-CD2 3.79Å; Y101-L240 HydrophobicContact CE2-CG 4.45Å; Y101-L240 VanDerWaalsContact CE2-O 3.27Å; Y101-L240 WeakPolarHBondContact CE2-O 3.45Å; Y101-L240 PolarHBondContact OH-O 3.01Å
102	I	98.3	Very high	96.8	Very high	51 Å²	51	37 Å²	37	26%	0.262	18%	0.184	S	C	.	.	H	α-helix	trans	-67.1	-44.5	178.5	-73	162.4	0	0	0	110.4	G98 F99 V100 A105 L106 V172 L176 V202	G98-I102 PolarHBondContact O-N 3.5Å; G98-I102 VanDerWaalsContact O-N 3.15Å; F99-I102 PolarHBondContact O-N 3.45Å; V100-I102 PolarHBondContact O-N 3.46Å; I102-A105 WeakPolarHBondContact O-CB 3.35Å; I102-A105 PolarHBondContact O-N 2.94Å; I102-L106 HydrophobicContact CG2-CD1 4.37Å; I102-L106 WeakPolarHBondContact O-CG 3.33Å; I102-L106 PolarHBondContact O-N 2.64Å; I102-V172 HydrophobicContact CD1-CG1 4.1Å; I102-V172 HydrophobicContact CG2-CG1 4.25Å; I102-L176 HydrophobicContact CD1-CD1 4.41Å; I102-V202 HydrophobicContact CD1-CG2 3.47Å; I102-V202 VanDerWaalsContact CD1-CG2 3.47Å
103	F	98.2	Very high	97	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-75.4	-25.4	-178.5	-81.2	-102	0	0	0	112.7	W66 Y69 M70 V73 F99 V100 L106 Y107 F123 N169	W66-F103 HydrophobicContact CE3-CE1 4.27Å; W66-F103 HydrophobicContact CZ3-CD1 4.28Å; W66-F103 AromaticContact CZ3-CE1 3.98Å; W66-F103 HydrophobicContact CZ3-CE1 3.98Å; Y69-F103 AromaticContact CD2-CD1 3.87Å; Y69-F103 HydrophobicContact CD2-CD1 3.87Å; Y69-F103 AromaticContact CD2-CE1 3.34Å; Y69-F103 HydrophobicContact CD2-CE1 3.34Å; Y69-F103 HydrophobicContact CD2-CZ 4.01Å; Y69-F103 AromaticContact CE2-CE1 3.92Å; Y69-F103 HydrophobicContact CE2-CE1 3.92Å; Y69-F103 HydrophobicContact CE2-CZ 4.16Å; Y69-F103 HydrophobicContact CG-CD1 4.14Å; Y69-F103 HydrophobicContact CG-CE1 4.05Å; M70-F103 HydrophobicContact CE-CD1 3.86Å; V73-F103 HydrophobicContact CG1-CB 3.7Å; F99-F103 AromaticContact CD2-CD2 3.28Å; F99-F103 HydrophobicContact CD2-CD2 3.28Å; F99-F103 AromaticContact CD2-CE2 3.48Å; F99-F103 HydrophobicContact CD2-CE2 3.48Å; F99-F103 VanDerWaalsContact CD2-CE2 3.48Å; F99-F103 AromaticContact CD2-CG 3.93Å; F99-F103 HydrophobicContact CD2-CG 3.93Å; F99-F103 HydrophobicContact CD2-CZ 4.26Å; F99-F103 HydrophobicContact CE2-CB 4.24Å; F99-F103 AromaticContact CE2-CD1 3.88Å; F99-F103 HydrophobicContact CE2-CD1 3.88Å; F99-F103 AromaticContact CE2-CD2 3.32Å; F99-F103 HydrophobicContact CE2-CD2 3.32Å; F99-F103 HydrophobicContact CE2-CE1 4.05Å; F99-F103 AromaticContact CE2-CE2 3.5Å; F99-F103 HydrophobicContact CE2-CE2 3.5Å; F99-F103 AromaticContact CE2-CG 3.52Å; F99-F103 HydrophobicContact CE2-CG 3.52Å; F99-F103 AromaticContact CE2-CZ 3.86Å; F99-F103 HydrophobicContact CE2-CZ 3.86Å; F99-F103 HydrophobicContact CG-CD2 4.11Å; F99-F103 HydrophobicContact CZ-CB 4.24Å; F99-F103 HydrophobicContact CZ-CD1 4.26Å; F99-F103 HydrophobicContact CZ-CD2 4.16Å; F99-F103 AromaticContact CZ-CG 3.95Å; F99-F103 HydrophobicContact CZ-CG 3.95Å; F99-F103 WeakPolarHBondContact O-CB 3.47Å; F99-F103 WeakPolarHBondContact O-CD2 3.35Å; F99-F103 PolarHBondContact O-N 2.94Å; V100-F103 PolarHBondContact O-N 3.48Å; F103-L106 HydrophobicContact CD1-CD1 4.09Å; F103-L106 HydrophobicContact CD2-CD1 4.49Å; F103-L106 HydrophobicContact CE1-CD1 4.1Å; F103-L106 HydrophobicContact CG-CD1 4.29Å; F103-L106 HydrophobicContact CZ-CD1 4.33Å; F103-L106 PolarHBondContact O-N 3.22Å; F103-Y107 VanDerWaalsContact O-CB 3.28Å; F103-Y107 WeakPolarHBondContact O-CB 3.21Å; F103-Y107 PolarHBondContact O-N 3.44Å; F103-F123 HydrophobicContact CE1-CZ 4.43Å; F103-F123 HydrophobicContact CZ-CZ 4.17Å; F103-N169 HydrophobicContact CE2-CB 3.63Å; F103-N169 HydrophobicContact CZ-CB 3.67Å
104	T	98	Very high	97.1	Very high	28 Å²	28	41 Å²	41	17%	0.172	21%	0.209	C	C	.	.	H	α-helix	trans	-62.1	-43.1	165.8	-66.9	0	0	0	0	111.3	I77 V100 L106 Y107 Y108	I77-T104 HydrophobicContact CD1-CG2 4.04Å; I77-T104 HydrophobicContact CG1-CG2 4.09Å; V100-T104 VanDerWaalsContact O-CB 3.28Å; V100-T104 WeakPolarHBondContact O-CB 3.28Å; V100-T104 PolarHBondContact O-N 3.04Å; V100-T104 PolarHBondContact O-OG1 2.78Å; T104-L106 VanDerWaalsContact C-N 3.35Å; T104-L106 PolarHBondContact O-N 3.42Å; T104-Y107 WeakPolarHBondContact O-CB 3.45Å; T104-Y107 PolarHBondContact O-N 3.5Å; T104-Y108 HydrophobicContact CG2-CD2 4Å; T104-Y108 HydrophobicContact CG2-CE2 3.62Å; T104-Y108 WeakPolarHBondContact O-CD2 3.3Å; T104-Y108 PolarHBondContact O-N 2.93Å; T104-Y108 VanDerWaalsContact O-N 3.15Å
105	A	98.2	Very high	97.4	Very high	49 Å²	49	43.9 Å²	43.9	41%	0.405	22%	0.224	S	C	.	.	H	α-helix	trans	-62.5	-43.9	174.9	0	0	0	0	0	111.2	Y101 I102 Y108 I109	Y101-A105 PolarHBondContact O-N 3.39Å; I102-A105 WeakPolarHBondContact O-CB 3.35Å; I102-A105 PolarHBondContact O-N 2.94Å; A105-Y108 PolarHBondContact O-N 3.17Å; A105-I109 WeakPolarHBondContact O-CD1 2.95Å; A105-I109 VanDerWaalsContact O-CG1 3.24Å; A105-I109 WeakPolarHBondContact O-CG1 3.47Å; A105-I109 PolarHBondContact O-N 3.29Å
106	L	98.1	Very high	97.4	Very high	9 Å²	9	44.7 Å²	44.7	5%	0.047	23%	0.229	C	C	.	.	H	α-helix	trans	-63.4	-40.3	175.8	-66.1	177.2	0	0	0	112.4	W66 I102 F103 T104 Y108 I109 T110 I122 F123 F126	W66-L106 HydrophobicContact CH2-CB 4.08Å; W66-L106 HydrophobicContact CH2-CD1 4.44Å; W66-L106 HydrophobicContact CZ3-CD1 4.28Å; I102-L106 HydrophobicContact CG2-CD1 4.37Å; I102-L106 WeakPolarHBondContact O-CG 3.33Å; I102-L106 PolarHBondContact O-N 2.64Å; F103-L106 HydrophobicContact CD1-CD1 4.09Å; F103-L106 HydrophobicContact CD2-CD1 4.49Å; F103-L106 HydrophobicContact CE1-CD1 4.1Å; F103-L106 HydrophobicContact CG-CD1 4.29Å; F103-L106 HydrophobicContact CZ-CD1 4.33Å; F103-L106 PolarHBondContact O-N 3.22Å; T104-L106 VanDerWaalsContact C-N 3.35Å; T104-L106 PolarHBondContact O-N 3.42Å; L106-Y108 PolarHBondContact O-N 2.82Å; L106-I109 PolarHBondContact O-N 2.95Å; L106-T110 WeakPolarHBondContact O-CB 3.36Å; L106-T110 WeakPolarHBondContact O-CG2 3.49Å; L106-T110 PolarHBondContact O-N 3.33Å; L106-T110 PolarHBondContact O-OG1 3.44Å; L106-I122 HydrophobicContact CD2-CD1 4.25Å; L106-I122 HydrophobicContact CD2-CG2 3.82Å; L106-F123 HydrophobicContact CD1-CE2 4.07Å; L106-F123 HydrophobicContact CD1-CZ 4.5Å; L106-F126 HydrophobicContact CD2-CZ 4.42Å
107	Y	98	Very high	97.5	Very high	8 Å²	8	50 Å²	50	3%	0.031	25%	0.249	C	C	.	.	H	α-helix	trans	-54.5	-51.8	175.7	174.5	-85.4	0	0	0	110	M70 V73 E74 I77 F103 T104 T110 R112 G113	M70-Y107 HydrophobicContact CB-CD2 4.08Å; M70-Y107 HydrophobicContact CB-CE2 4.49Å; M70-Y107 HydrophobicContact CG-CD2 4.47Å; M70-Y107 HydrophobicContact SD-CD2 3.84Å; M70-Y107 HydrophobicContact SD-CG 4.33Å; V73-Y107 HydrophobicContact CG2-CD2 4.02Å; V73-Y107 HydrophobicContact CG2-CG 4.16Å; E74-Y107 HydrophobicContact CB-CE2 4Å; E74-Y107 HydrophobicContact CG-CE2 4.48Å; E74-Y107 PolarHBondContact OE1-OH 3.31Å; I77-Y107 HydrophobicContact CD1-CD1 3.63Å; I77-Y107 HydrophobicContact CD1-CE1 3.75Å; I77-Y107 HydrophobicContact CD1-CG 4.18Å; F103-Y107 VanDerWaalsContact O-CB 3.28Å; F103-Y107 WeakPolarHBondContact O-CB 3.21Å; F103-Y107 PolarHBondContact O-N 3.44Å; T104-Y107 WeakPolarHBondContact O-CB 3.45Å; T104-Y107 PolarHBondContact O-N 3.5Å; Y107-T110 PolarHBondContact O-N 2.83Å; Y107-T110 PolarHBondContact O-OG1 3.36Å; Y107-R112 HydrophobicContact CD1-CB 4.4Å; Y107-R112 HydrophobicContact CD1-CG 4.34Å; Y107-R112 HydrophobicContact CD2-CB 4.33Å; Y107-R112 HydrophobicContact CE1-CB 3.8Å; Y107-R112 HydrophobicContact CE1-CG 3.57Å; Y107-R112 HydrophobicContact CE2-CB 3.74Å; Y107-R112 HydrophobicContact CE2-CG 4.4Å; Y107-R112 VanDerWaalsContact CZ-CB 3.43Å; Y107-R112 WeakPolarHBondContact O-CA 3.47Å; Y107-R112 PolarHBondContact O-N 3.49Å; Y107-R112 WeakPolarHBondContact OH-CD 3.49Å; Y107-G113 PolarHBondContact O-N 2.84Å
108	Y	98.2	Very high	97.5	Very high	137 Å²	137	52.8 Å²	52.8	54%	0.537	26%	0.264	S	S	.	.	H	α-helix	trans	-66.1	-43.8	178.7	-70.9	-61.9	0	0	0	113.5	I77 T104 A105 L106 T110 S111	I77-Y108 HydrophobicContact CD1-CE2 4.1Å; I77-Y108 VanDerWaalsContact CG2-OH 3.3Å; I77-Y108 WeakPolarHBondContact CG2-OH 3.41Å; T104-Y108 HydrophobicContact CG2-CD2 4Å; T104-Y108 HydrophobicContact CG2-CE2 3.62Å; T104-Y108 WeakPolarHBondContact O-CD2 3.3Å; T104-Y108 PolarHBondContact O-N 2.93Å; T104-Y108 VanDerWaalsContact O-N 3.15Å; A105-Y108 PolarHBondContact O-N 3.17Å; L106-Y108 PolarHBondContact O-N 2.82Å; Y108-T110 VanDerWaalsContact C-N 3.28Å; Y108-T110 PolarHBondContact O-N 3.4Å; Y108-S111 PolarHBondContact O-N 2.66Å
109	I	98.2	Very high	97.5	Very high	95 Å²	95	52.6 Å²	52.6	49%	0.487	26%	0.262	S	S	.	.	H	α-helix	trans	-62.1	-37.7	-179.3	-68.1	164.8	0	0	0	111.4	A105 L106 S111 L118 I122	A105-I109 WeakPolarHBondContact O-CD1 2.95Å; A105-I109 VanDerWaalsContact O-CG1 3.24Å; A105-I109 WeakPolarHBondContact O-CG1 3.47Å; A105-I109 PolarHBondContact O-N 3.29Å; L106-I109 PolarHBondContact O-N 2.95Å; I109-S111 VanDerWaalsContact C-N 3.28Å; I109-S111 PolarHBondContact O-N 3.15Å; I109-L118 HydrophobicContact CG2-CD2 3.99Å; I109-L118 VanDerWaalsContact O-CD2 3.28Å; I109-L118 WeakPolarHBondContact O-CD2 3.25Å; I109-I122 HydrophobicContact CG2-CD1 3.68Å
110	T	97.8	Very high	97.5	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	26%	0.263	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.5	23.6	-175.2	60.2	0	0	0	0	113.4	W66 L106 Y107 Y108 G113 V114 N115 L118 I122	W66-T110 HydrophobicContact CH2-CG2 4.36Å; W66-T110 HydrophobicContact CZ2-CG2 4.18Å; L106-T110 WeakPolarHBondContact O-CB 3.36Å; L106-T110 WeakPolarHBondContact O-CG2 3.49Å; L106-T110 PolarHBondContact O-N 3.33Å; L106-T110 PolarHBondContact O-OG1 3.44Å; Y107-T110 PolarHBondContact O-N 2.83Å; Y107-T110 PolarHBondContact O-OG1 3.36Å; Y108-T110 VanDerWaalsContact C-N 3.28Å; Y108-T110 PolarHBondContact O-N 3.4Å; T110-G113 PolarHBondContact O-N 3.37Å; T110-G113 VanDerWaalsContact OG1-CA 3.27Å; T110-G113 WeakPolarHBondContact OG1-CA 3.3Å; T110-G113 PolarHBondContact OG1-N 2.84Å; T110-V114 PolarHBondContact O-N 3.17Å; T110-N115 VanDerWaalsContact O-CB 3.32Å; T110-N115 WeakPolarHBondContact O-CB 3.13Å; T110-N115 PolarHBondContact O-N 3.24Å; T110-L118 HydrophobicContact CG2-CG 4.5Å; T110-I122 HydrophobicContact CG2-CD1 4.26Å
111	S	97.5	Very high	97.5	Very high	77 Å²	77	57 Å²	57	54%	0.538	28%	0.279	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.3	54.7	-178.5	-49.6	0	0	0	0	111.7	Y108 I109 G113 V114	Y108-S111 PolarHBondContact O-N 2.66Å; I109-S111 VanDerWaalsContact C-N 3.28Å; I109-S111 PolarHBondContact O-N 3.15Å; S111-G113 VanDerWaalsContact C-N 3.33Å; S111-G113 PolarHBondContact O-N 2.79Å; S111-V114 WeakPolarHBondContact O-CG2 3.24Å; S111-V114 PolarHBondContact O-N 2.99Å
112	R	96.1	Very high	97.5	Very high	168 Å²	168	54.4 Å²	54.4	63%	0.634	27%	0.271	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.9	35.6	-177.1	-51.1	-176.8	-176	-169.2	1.9	113.1	Y107 V114	Y107-R112 HydrophobicContact CD1-CB 4.4Å; Y107-R112 HydrophobicContact CD1-CG 4.34Å; Y107-R112 HydrophobicContact CD2-CB 4.33Å; Y107-R112 HydrophobicContact CE1-CB 3.8Å; Y107-R112 HydrophobicContact CE1-CG 3.57Å; Y107-R112 HydrophobicContact CE2-CB 3.74Å; Y107-R112 HydrophobicContact CE2-CG 4.4Å; Y107-R112 VanDerWaalsContact CZ-CB 3.43Å; Y107-R112 WeakPolarHBondContact O-CA 3.47Å; Y107-R112 PolarHBondContact O-N 3.49Å; Y107-R112 WeakPolarHBondContact OH-CD 3.49Å; R112-V114 VanDerWaalsContact C-N 3.29Å; R112-V114 PolarHBondContact O-N 3.37Å
113	G	94.4	Very high	97.5	Very high	7 Å²	7	52 Å²	52	7%	0.072	26%	0.258	C	S	.	.	T	Hydrogen-bonded Turn	trans	81.8	-4	-179.5	0	0	0	0	0	116.1	W66 M70 Y107 T110 S111 I116	W66-G113 PolarHBondContact NE1-O 3.2Å; M70-G113 VanDerWaalsContact SD-CA 3.56Å; Y107-G113 PolarHBondContact O-N 2.84Å; T110-G113 PolarHBondContact O-N 3.37Å; T110-G113 VanDerWaalsContact OG1-CA 3.27Å; T110-G113 WeakPolarHBondContact OG1-CA 3.3Å; T110-G113 PolarHBondContact OG1-N 2.84Å; S111-G113 VanDerWaalsContact C-N 3.33Å; S111-G113 PolarHBondContact O-N 2.79Å; G113-I116 VanDerWaalsContact O-CD1 3.24Å; G113-I116 WeakPolarHBondContact O-CD1 3.46Å
114	V	96.3	Very high	97.5	Very high	117 Å²	117	52.4 Å²	52.4	71%	0.709	26%	0.262	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.8	-34.9	-177.2	-179.6	0	0	0	0	111.9	T110 S111 R112 I116	T110-V114 PolarHBondContact O-N 3.17Å; S111-V114 WeakPolarHBondContact O-CG2 3.24Å; S111-V114 PolarHBondContact O-N 2.99Å; R112-V114 VanDerWaalsContact C-N 3.29Å; R112-V114 PolarHBondContact O-N 3.37Å; V114-I116 VanDerWaalsContact C-N 3.25Å; V114-I116 PolarHBondContact O-N 3.02Å
115	N	97.3	Very high	97.5	Very high	65 Å²	65	55 Å²	55	35%	0.348	28%	0.277	S	S	.	.			trans	-81.6	71.9	178.9	-166.7	-16.2	0	0	0	111.2	T110 R117 L118 G119	T110-N115 VanDerWaalsContact O-CB 3.32Å; T110-N115 WeakPolarHBondContact O-CB 3.13Å; T110-N115 PolarHBondContact O-N 3.24Å; N115-R117 PolarHBondContact O-N 3.28Å; N115-L118 HydrophobicContact CB-CB 4.22Å; N115-L118 VanDerWaalsContact CG-CB 3.49Å; N115-L118 PolarHBondContact O-N 3.26Å; N115-L118 WeakPolarHBondContact OD1-CB 3.44Å; N115-L118 PolarHBondContact OD1-N 3.34Å; N115-G119 PolarHBondContact O-N 3.12Å; N115-G119 VanDerWaalsContact O-N 3.15Å
116	I	96.6	Very high	97.5	Very high	36 Å²	36	54.4 Å²	54.4	19%	0.185	27%	0.266	C	S	.	.	H	α-helix	trans	-56.1	-40.1	178.6	-55.8	-59.1	0	0	0	111	Y61 W66 G113 V114 L118 G119 Q120 L167	Y61-I116 HydrophobicContact CD1-CG2 3.93Å; Y61-I116 HydrophobicContact CD2-CG2 3.77Å; Y61-I116 HydrophobicContact CE1-CG2 3.99Å; Y61-I116 HydrophobicContact CE2-CG2 3.87Å; Y61-I116 HydrophobicContact CG-CG2 3.81Å; W66-I116 HydrophobicContact CG-CD1 4.25Å; G113-I116 VanDerWaalsContact O-CD1 3.24Å; G113-I116 WeakPolarHBondContact O-CD1 3.46Å; V114-I116 VanDerWaalsContact C-N 3.25Å; V114-I116 PolarHBondContact O-N 3.02Å; I116-L118 VanDerWaalsContact C-N 3.33Å; I116-L118 PolarHBondContact O-N 2.87Å; I116-G119 CarbonylContact O-C 3.33Å; I116-G119 WeakPolarHBondContact O-CA 3.47Å; I116-G119 PolarHBondContact O-N 2.86Å; I116-Q120 HydrophobicContact CG2-CG 4.22Å; I116-Q120 WeakPolarHBondContact O-CG 3.28Å; I116-Q120 PolarHBondContact O-N 2.98Å; I116-L167 HydrophobicContact CG2-CD1 4.28Å
117	R	97	Very high	97.5	Very high	112 Å²	112	54 Å²	54	42%	0.423	26%	0.264	S	S	.	.	H	α-helix	trans	-60.1	-43.1	-178.3	-175.6	68	101.8	-161	12.9	111.8	I56 N115 G119 Q120 Y121	I56-R117 PolarHBondContact O-NH1 3.23Å; N115-R117 PolarHBondContact O-N 3.28Å; R117-G119 VanDerWaalsContact C-N 3.34Å; R117-Q120 PolarHBondContact O-N 3.36Å; R117-Y121 HydrophobicContact CG-CD2 4.3Å; R117-Y121 HydrophobicContact CG-CE2 3.71Å; R117-Y121 WeakPolarHBondContact O-CD2 3.38Å; R117-Y121 PolarHBondContact O-N 3.18Å
118	L	97.7	Very high	97.5	Very high	59 Å²	59	54.7 Å²	54.7	31%	0.309	27%	0.268	S	S	.	.	H	α-helix	trans	-63.4	-42.3	173	180	58.1	0	0	0	111.2	I109 T110 N115 I116 Q120 Y121 I122	I109-L118 HydrophobicContact CG2-CD2 3.99Å; I109-L118 VanDerWaalsContact O-CD2 3.28Å; I109-L118 WeakPolarHBondContact O-CD2 3.25Å; T110-L118 HydrophobicContact CG2-CG 4.5Å; N115-L118 HydrophobicContact CB-CB 4.22Å; N115-L118 VanDerWaalsContact CG-CB 3.49Å; N115-L118 PolarHBondContact O-N 3.26Å; N115-L118 WeakPolarHBondContact OD1-CB 3.44Å; N115-L118 PolarHBondContact OD1-N 3.34Å; I116-L118 VanDerWaalsContact C-N 3.33Å; I116-L118 PolarHBondContact O-N 2.87Å; L118-Q120 VanDerWaalsContact C-N 3.34Å; L118-Q120 PolarHBondContact O-N 2.87Å; L118-Y121 PolarHBondContact O-N 3.18Å; L118-I122 HydrophobicContact CD1-CD1 4.44Å; L118-I122 HydrophobicContact CG-CD1 4.13Å; L118-I122 WeakPolarHBondContact O-CG1 3.26Å; L118-I122 PolarHBondContact O-N 2.76Å
119	G	97.6	Very high	97.5	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-54	-47.2	172	0	0	0	0	0	112.8	N115 I116 R117 Y121 I122 F123	N115-G119 PolarHBondContact O-N 3.12Å; N115-G119 VanDerWaalsContact O-N 3.15Å; I116-G119 CarbonylContact O-C 3.33Å; I116-G119 WeakPolarHBondContact O-CA 3.47Å; I116-G119 PolarHBondContact O-N 2.86Å; R117-G119 VanDerWaalsContact C-N 3.34Å; G119-Y121 VanDerWaalsContact C-N 3.33Å; G119-Y121 PolarHBondContact O-N 2.99Å; G119-I122 PolarHBondContact O-N 2.96Å; G119-I122 VanDerWaalsContact O-N 3.16Å; G119-F123 WeakPolarHBondContact O-CD2 3.32Å; G119-F123 PolarHBondContact O-N 3.45Å
120	Q	98.1	Very high	97.4	Very high	5 Å²	5	46.4 Å²	46.4	2%	0.023	24%	0.236	C	C	.	.	H	α-helix	trans	-59.3	-41.3	177.1	-62.3	-174	-68.8	0	0	112.4	I56 I116 R117 L118 F123 A124 V164 L167	I56-Q120 HydrophobicContact CD1-CB 4.13Å; I56-Q120 HydrophobicContact CG1-CB 4.08Å; I56-Q120 HydrophobicContact CG2-CB 4.23Å; I116-Q120 HydrophobicContact CG2-CG 4.22Å; I116-Q120 WeakPolarHBondContact O-CG 3.28Å; I116-Q120 PolarHBondContact O-N 2.98Å; R117-Q120 PolarHBondContact O-N 3.36Å; L118-Q120 VanDerWaalsContact C-N 3.34Å; L118-Q120 PolarHBondContact O-N 2.87Å; Q120-F123 PolarHBondContact O-N 3.44Å; Q120-A124 WeakPolarHBondContact O-CB 3.19Å; Q120-A124 PolarHBondContact O-N 3.44Å; Q120-V164 VanDerWaalsContact CG-O 3.3Å; Q120-V164 WeakPolarHBondContact CG-O 3.3Å; Q120-V164 PolarHBondContact NE2-O 3.15Å; Q120-L167 HydrophobicContact CG-CD2 4.26Å
121	Y	98.3	Very high	97.4	Very high	87 Å²	87	46.4 Å²	46.4	34%	0.341	24%	0.236	S	C	.	.	H	α-helix	trans	-67	-39.2	176	-68.2	-50.9	0	0	0	112.5	L53 I56 R117 L118 G119 F123 A124 V125	L53-Y121 HydrophobicContact CD2-CD1 4.29Å; L53-Y121 HydrophobicContact CD2-CE1 3.8Å; I56-Y121 HydrophobicContact CD1-CD1 3.73Å; I56-Y121 HydrophobicContact CD1-CE1 3.97Å; I56-Y121 HydrophobicContact CG2-CE1 3.99Å; R117-Y121 HydrophobicContact CG-CD2 4.3Å; R117-Y121 HydrophobicContact CG-CE2 3.71Å; R117-Y121 WeakPolarHBondContact O-CD2 3.38Å; R117-Y121 PolarHBondContact O-N 3.18Å; L118-Y121 PolarHBondContact O-N 3.18Å; G119-Y121 VanDerWaalsContact C-N 3.33Å; G119-Y121 PolarHBondContact O-N 2.99Å; Y121-F123 VanDerWaalsContact C-N 3.34Å; Y121-A124 WeakPolarHBondContact O-CB 3.43Å; Y121-A124 PolarHBondContact O-N 3.42Å; Y121-V125 WeakPolarHBondContact O-CG2 3.29Å; Y121-V125 PolarHBondContact O-N 3.23Å
122	I	98.5	Very high	97.3	Very high	32 Å²	32	46.8 Å²	46.8	16%	0.164	23%	0.231	C	C	.	.	H	α-helix	trans	-62.2	-44.6	174.4	-66.5	165.9	0	0	0	110.3	L106 I109 T110 L118 G119 A124 V125 F126	L106-I122 HydrophobicContact CD2-CD1 4.25Å; L106-I122 HydrophobicContact CD2-CG2 3.82Å; I109-I122 HydrophobicContact CG2-CD1 3.68Å; T110-I122 HydrophobicContact CG2-CD1 4.26Å; L118-I122 HydrophobicContact CD1-CD1 4.44Å; L118-I122 HydrophobicContact CG-CD1 4.13Å; L118-I122 WeakPolarHBondContact O-CG1 3.26Å; L118-I122 PolarHBondContact O-N 2.76Å; G119-I122 PolarHBondContact O-N 2.96Å; G119-I122 VanDerWaalsContact O-N 3.16Å; I122-A124 VanDerWaalsContact C-N 3.32Å; I122-A124 PolarHBondContact O-N 3.04Å; I122-V125 WeakPolarHBondContact O-CA 3.21Å; I122-V125 WeakPolarHBondContact O-CB 3.3Å; I122-V125 PolarHBondContact O-N 3.17Å; I122-V125 VanDerWaalsContact O-N 3.1Å; I122-F126 HydrophobicContact CG2-CD2 4.37Å; I122-F126 HydrophobicContact CG2-CE1 3.97Å; I122-F126 HydrophobicContact CG2-CE2 3.76Å; I122-F126 HydrophobicContact CG2-CZ 3.53Å; I122-F126 PolarHBondContact O-N 3.35Å
123	F	98.3	Very high	97.4	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-67.9	-30.2	176.9	-90.1	-97	0	0	0	113.4	W66 F103 L106 G119 Q120 Y121 V125 F126 Y127 F163 L167 F168 P171 V172	W66-F123 AromaticContact CZ3-CE2 3.89Å; W66-F123 HydrophobicContact CZ3-CE2 3.89Å; F103-F123 HydrophobicContact CE1-CZ 4.43Å; F103-F123 HydrophobicContact CZ-CZ 4.17Å; L106-F123 HydrophobicContact CD1-CE2 4.07Å; L106-F123 HydrophobicContact CD1-CZ 4.5Å; G119-F123 WeakPolarHBondContact O-CD2 3.32Å; G119-F123 PolarHBondContact O-N 3.45Å; Q120-F123 PolarHBondContact O-N 3.44Å; Y121-F123 VanDerWaalsContact C-N 3.34Å; F123-V125 VanDerWaalsContact C-N 3.33Å; F123-F126 HydrophobicContact CD1-CD2 4.13Å; F123-F126 HydrophobicContact CD2-CD2 4.31Å; F123-F126 HydrophobicContact CD2-CE2 4.42Å; F123-F126 HydrophobicContact CE1-CD2 4.27Å; F123-F126 HydrophobicContact CE2-CD2 4.48Å; F123-F126 HydrophobicContact CE2-CE2 4.32Å; F123-F126 HydrophobicContact CG-CD2 4.17Å; F123-F126 HydrophobicContact CZ-CD2 4.46Å; F123-F126 HydrophobicContact CZ-CE2 4.48Å; F123-F126 PolarHBondContact O-N 2.91Å; F123-Y127 WeakPolarHBondContact O-CB 3.43Å; F123-Y127 PolarHBondContact O-N 3.44Å; F123-F163 WeakPolarHBondContact CB-O 3.49Å; F123-F163 VanDerWaalsContact CD1-O 3.23Å; F123-F163 WeakPolarHBondContact CD1-O 3.26Å; F123-F163 WeakPolarHBondContact CG-O 3.46Å; F123-L167 HydrophobicContact CB-CD2 3.65Å; F123-L167 HydrophobicContact CD1-CB 4.45Å; F123-L167 HydrophobicContact CD1-CD2 4.27Å; F123-L167 HydrophobicContact CD2-CB 4.04Å; F123-L167 HydrophobicContact CD2-CD2 3.48Å; F123-L167 VanDerWaalsContact CD2-CD2 3.48Å; F123-L167 HydrophobicContact CD2-CG 4.28Å; F123-L167 VanDerWaalsContact CE1-C 3.49Å; F123-L167 HydrophobicContact CE1-CB 4.29Å; F123-L167 HydrophobicContact CE2-CB 3.83Å; F123-L167 HydrophobicContact CE2-CD2 4.17Å; F123-L167 HydrophobicContact CG-CB 4.32Å; F123-L167 HydrophobicContact CG-CD2 3.51Å; F123-L167 HydrophobicContact CZ-CB 3.96Å; F123-L167 VanDerWaalsContact CZ-O 3.29Å; F123-L167 WeakPolarHBondContact CZ-O 3.5Å; F123-F168 VanDerWaalsContact CE1-O 3.22Å; F123-F168 WeakPolarHBondContact CE1-O 3.42Å; F123-P171 HydrophobicContact CE1-CB 4.37Å; F123-V172 HydrophobicContact CE1-CG2 4.3Å; F123-V172 HydrophobicContact CZ-CG2 4.39Å
124	A	97.8	Very high	97.5	Very high	9 Å²	9	40 Å²	40	7%	0.074	21%	0.206	C	C	.	.	H	α-helix	trans	-64.4	-39.4	169.7	0	0	0	0	0	111.1	N52 I56 Q120 Y121 I122 Y127 L128 V164	N52-A124 HydrophobicContact CB-CB 4.11Å; I56-A124 HydrophobicContact CD1-CB 4Å; Q120-A124 WeakPolarHBondContact O-CB 3.19Å; Q120-A124 PolarHBondContact O-N 3.44Å; Y121-A124 WeakPolarHBondContact O-CB 3.43Å; Y121-A124 PolarHBondContact O-N 3.42Å; I122-A124 VanDerWaalsContact C-N 3.32Å; I122-A124 PolarHBondContact O-N 3.04Å; A124-Y127 WeakPolarHBondContact O-CB 3.17Å; A124-Y127 PolarHBondContact O-N 2.76Å; A124-L128 VanDerWaalsContact O-CG 3.29Å; A124-L128 WeakPolarHBondContact O-CG 3.32Å; A124-L128 PolarHBondContact O-N 2.69Å; A124-V164 HydrophobicContact CB-CG1 3.85Å
125	V	98.3	Very high	97.5	Very high	82 Å²	82	34.8 Å²	34.8	50%	0.497	17%	0.174	S	C	.	.	H	α-helix	trans	-63.3	-44.7	172.2	174.4	0	0	0	0	110.9	Y121 I122 F123 Y127 L128 V129	Y121-V125 WeakPolarHBondContact O-CG2 3.29Å; Y121-V125 PolarHBondContact O-N 3.23Å; I122-V125 WeakPolarHBondContact O-CA 3.21Å; I122-V125 WeakPolarHBondContact O-CB 3.3Å; I122-V125 PolarHBondContact O-N 3.17Å; I122-V125 VanDerWaalsContact O-N 3.1Å; F123-V125 VanDerWaalsContact C-N 3.33Å; V125-Y127 VanDerWaalsContact C-N 3.27Å; V125-Y127 PolarHBondContact O-N 3.03Å; V125-L128 PolarHBondContact O-N 3.3Å; V125-V129 HydrophobicContact CG1-CG2 4.27Å; V125-V129 WeakPolarHBondContact O-CG2 3.25Å; V125-V129 PolarHBondContact O-N 3.13Å
126	F	98.3	Very high	97.4	Very high	37 Å²	37	36.4 Å²	36.4	16%	0.162	18%	0.175	C	C	.	.	H	α-helix	trans	-58.5	-40.2	175	-64.5	-19.7	0	0	0	112.4	L106 I122 F123 T130 F163 V172 M175	L106-F126 HydrophobicContact CD2-CZ 4.42Å; I122-F126 HydrophobicContact CG2-CD2 4.37Å; I122-F126 HydrophobicContact CG2-CE1 3.97Å; I122-F126 HydrophobicContact CG2-CE2 3.76Å; I122-F126 HydrophobicContact CG2-CZ 3.53Å; I122-F126 PolarHBondContact O-N 3.35Å; F123-F126 HydrophobicContact CD1-CD2 4.13Å; F123-F126 HydrophobicContact CD2-CD2 4.31Å; F123-F126 HydrophobicContact CD2-CE2 4.42Å; F123-F126 HydrophobicContact CE1-CD2 4.27Å; F123-F126 HydrophobicContact CE2-CD2 4.48Å; F123-F126 HydrophobicContact CE2-CE2 4.32Å; F123-F126 HydrophobicContact CG-CD2 4.17Å; F123-F126 HydrophobicContact CZ-CD2 4.46Å; F123-F126 HydrophobicContact CZ-CE2 4.48Å; F123-F126 PolarHBondContact O-N 2.91Å; F126-T130 WeakPolarHBondContact O-CB 3.43Å; F126-T130 PolarHBondContact O-N 3.43Å; F126-T130 PolarHBondContact O-OG1 3.23Å; F126-F163 HydrophobicContact CB-CD1 4.45Å; F126-F163 HydrophobicContact CB-CE1 4.38Å; F126-V172 HydrophobicContact CD2-CG2 3.89Å; F126-V172 HydrophobicContact CE2-CG2 3.9Å; F126-M175 HydrophobicContact CB-SD 4.01Å; F126-M175 HydrophobicContact CD1-CE 3.86Å; F126-M175 HydrophobicContact CD1-SD 4.03Å; F126-M175 HydrophobicContact CE1-CE 4.29Å; F126-M175 HydrophobicContact CG-CE 4.24Å; F126-M175 HydrophobicContact CG-SD 4.28Å
127	Y	97.3	Very high	97.4	Very high	1 Å²	1	34.8 Å²	34.8	0%	0.004	17%	0.167	C	C	.	.	H	α-helix	trans	-62.3	-50.3	174.6	175.1	-101.3	0	0	0	111.9	E48 N52 F123 A124 V125 V129 T130 L131 I159 H160 F163	E48-Y127 HydrophobicContact CB-CE1 4.33Å; E48-Y127 HydrophobicContact CG-CE1 4.48Å; E48-Y127 WeakPolarHBondContact OE2-CE1 3.17Å; E48-Y127 VanDerWaalsContact OE2-CZ 3.27Å; E48-Y127 PolarHBondContact OE2-OH 2.84Å; N52-Y127 WeakPolarHBondContact ND2-CD1 3.25Å; N52-Y127 WeakPolarHBondContact ND2-CE1 3.43Å; F123-Y127 WeakPolarHBondContact O-CB 3.43Å; F123-Y127 PolarHBondContact O-N 3.44Å; A124-Y127 WeakPolarHBondContact O-CB 3.17Å; A124-Y127 PolarHBondContact O-N 2.76Å; V125-Y127 VanDerWaalsContact C-N 3.27Å; V125-Y127 PolarHBondContact O-N 3.03Å; Y127-V129 VanDerWaalsContact C-N 3.34Å; Y127-V129 PolarHBondContact O-N 3.04Å; Y127-T130 WeakPolarHBondContact O-CB 3.37Å; Y127-T130 PolarHBondContact O-N 3.25Å; Y127-T130 VanDerWaalsContact O-N 3.14Å; Y127-L131 HydrophobicContact CD1-CD1 4.13Å; Y127-L131 HydrophobicContact CE1-CD1 3.4Å; Y127-L131 VanDerWaalsContact CE1-CD1 3.4Å; Y127-L131 HydrophobicContact CE1-CG 4.1Å; Y127-L131 HydrophobicContact CE2-CD1 4.33Å; Y127-L131 HydrophobicContact CE2-CD2 4.48Å; Y127-L131 HydrophobicContact CE2-CG 4.27Å; Y127-L131 PolarHBondContact O-N 2.99Å; Y127-I159 HydrophobicContact CD2-CG2 4.21Å; Y127-I159 HydrophobicContact CE2-CG2 3.75Å; Y127-H160 AromaticContact CZ-NE2 3.93Å; Y127-H160 PolarHBondContact OH-CE1 3.09Å; Y127-F163 VanDerWaalsContact CA-CE1 3.42Å; Y127-F163 VanDerWaalsContact CB-CD1 3.45Å; Y127-F163 HydrophobicContact CD2-CB 4.49Å; Y127-F163 HydrophobicContact CD2-CD1 4.18Å; Y127-F163 AromaticContact CD2-CD2 3.93Å; Y127-F163 HydrophobicContact CD2-CD2 3.93Å; Y127-F163 HydrophobicContact CD2-CE1 4.31Å; Y127-F163 HydrophobicContact CD2-CE2 4.09Å; Y127-F163 AromaticContact CD2-CG 3.96Å; Y127-F163 HydrophobicContact CD2-CG 3.96Å; Y127-F163 HydrophobicContact CD2-CZ 4.29Å; Y127-F163 HydrophobicContact CG-CD1 4.31Å; Y127-F163 HydrophobicContact CG-CG 4.36Å
128	L	97.3	Very high	97.3	Very high	22 Å²	22	29.5 Å²	29.5	12%	0.115	15%	0.147	C	C	.	.	H	α-helix	trans	-62.8	-39.2	-179.8	-69.5	171.2	0	0	0	112.4	W45 E48 I49 A124 V125 L131 L132	W45-L128 HydrophobicContact CZ2-CB 4.03Å; W45-L128 HydrophobicContact CZ2-CD2 4.48Å; W45-L128 PolarHBondContact NE1-O 2.87Å; E48-L128 HydrophobicContact CB-CD2 4.01Å; I49-L128 HydrophobicContact CG1-CD1 3.85Å; I49-L128 HydrophobicContact CG1-CD2 3.97Å; A124-L128 VanDerWaalsContact O-CG 3.29Å; A124-L128 WeakPolarHBondContact O-CG 3.32Å; A124-L128 PolarHBondContact O-N 2.69Å; V125-L128 PolarHBondContact O-N 3.3Å; L128-L131 PolarHBondContact O-N 2.74Å; L128-L132 WeakPolarHBondContact O-CG 3.44Å; L128-L132 PolarHBondContact O-N 3.33Å; L128-L132 VanDerWaalsContact O-N 3.08Å
129	V	98.3	Very high	97	Very high	58 Å²	58	29.1 Å²	29.1	35%	0.352	15%	0.145	S	C	.	.	H	α-helix	trans	-64.9	-43.9	173.6	171.2	0	0	0	0	110.6	V125 Y127 L131 L132 L133 M175	V125-V129 HydrophobicContact CG1-CG2 4.27Å; V125-V129 WeakPolarHBondContact O-CG2 3.25Å; V125-V129 PolarHBondContact O-N 3.13Å; Y127-V129 VanDerWaalsContact C-N 3.34Å; Y127-V129 PolarHBondContact O-N 3.04Å; V129-L131 VanDerWaalsContact C-N 3.3Å; V129-L131 PolarHBondContact O-N 3.11Å; V129-L132 PolarHBondContact O-N 3.36Å; V129-L133 HydrophobicContact CG1-CD1 3.99Å; V129-L133 HydrophobicContact CG1-CG 4.44Å; V129-L133 WeakPolarHBondContact O-CG 3.44Å; V129-L133 PolarHBondContact O-N 3.45Å; V129-M175 HydrophobicContact CB-SD 3.98Å; V129-M175 HydrophobicContact CG1-CG 4.07Å; V129-M175 HydrophobicContact CG1-SD 3.78Å
130	T	97.9	Very high	96.7	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-56.5	-46.3	175.5	-61.2	0	0	0	0	110.9	F126 Y127 L132 L133 V134 F163 M175 F178	F126-T130 WeakPolarHBondContact O-CB 3.43Å; F126-T130 PolarHBondContact O-N 3.43Å; F126-T130 PolarHBondContact O-OG1 3.23Å; Y127-T130 WeakPolarHBondContact O-CB 3.37Å; Y127-T130 PolarHBondContact O-N 3.25Å; Y127-T130 VanDerWaalsContact O-N 3.14Å; T130-L132 PolarHBondContact O-N 3.42Å; T130-L133 PolarHBondContact O-N 3.49Å; T130-V134 HydrophobicContact CG2-CG2 4.33Å; T130-V134 WeakPolarHBondContact O-CB 3.48Å; T130-V134 VanDerWaalsContact O-CG2 3.26Å; T130-V134 WeakPolarHBondContact O-CG2 3.49Å; T130-V134 PolarHBondContact O-N 2.84Å; T130-F163 HydrophobicContact CG2-CZ 4.3Å; T130-M175 VanDerWaalsContact OG1-CB 3.32Å; T130-M175 WeakPolarHBondContact OG1-CB 3.4Å; T130-M175 WeakPolarHBondContact OG1-CG 3.32Å; T130-F178 HydrophobicContact CG2-CD2 3.91Å; T130-F178 HydrophobicContact CG2-CE2 4.22Å
131	L	96.1	Very high	96.3	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-60.8	-43.7	176.8	-74.2	-176.4	0	0	0	112.5	E48 Y127 L128 V129 L133 V134 F135 V152	E48-L131 HydrophobicContact CB-CD1 4.07Å; E48-L131 HydrophobicContact CG-CD1 3.77Å; Y127-L131 HydrophobicContact CD1-CD1 4.13Å; Y127-L131 HydrophobicContact CE1-CD1 3.4Å; Y127-L131 VanDerWaalsContact CE1-CD1 3.4Å; Y127-L131 HydrophobicContact CE1-CG 4.1Å; Y127-L131 HydrophobicContact CE2-CD1 4.33Å; Y127-L131 HydrophobicContact CE2-CD2 4.48Å; Y127-L131 HydrophobicContact CE2-CG 4.27Å; Y127-L131 PolarHBondContact O-N 2.99Å; L128-L131 PolarHBondContact O-N 2.74Å; V129-L131 VanDerWaalsContact C-N 3.3Å; V129-L131 PolarHBondContact O-N 3.11Å; L131-L133 VanDerWaalsContact C-N 3.32Å; L131-L133 PolarHBondContact O-N 2.97Å; L131-V134 PolarHBondContact O-N 2.88Å; L131-F135 HydrophobicContact CB-CD2 4.43Å; L131-F135 HydrophobicContact CB-CE2 4.22Å; L131-F135 WeakPolarHBondContact O-CB 3.47Å; L131-F135 VanDerWaalsContact O-CD2 3.25Å; L131-F135 WeakPolarHBondContact O-CD2 3.29Å; L131-F135 WeakPolarHBondContact O-CG 3.44Å; L131-F135 PolarHBondContact O-N 2.71Å; L131-V152 HydrophobicContact CD2-CG1 4.49Å
132	L	96.6	Very high	95.8	Very high	85 Å²	85	33.5 Å²	33.5	45%	0.445	17%	0.165	S	C	.	.	H	α-helix	trans	-59	-44.4	176.3	-71.2	173.3	0	0	0	111.9	W45 L128 V129 T130 F135 R136	W45-L132 HydrophobicContact CD2-CD2 4.05Å; W45-L132 HydrophobicContact CG-CD2 3.95Å; W45-L132 HydrophobicContact CZ2-CD1 3.88Å; W45-L132 HydrophobicContact CZ2-CD2 4.5Å; W45-L132 HydrophobicContact CZ2-CG 4.28Å; W45-L132 VanDerWaalsContact NE1-CG 3.34Å; L128-L132 WeakPolarHBondContact O-CG 3.44Å; L128-L132 PolarHBondContact O-N 3.33Å; L128-L132 VanDerWaalsContact O-N 3.08Å; V129-L132 PolarHBondContact O-N 3.36Å; T130-L132 PolarHBondContact O-N 3.42Å; L132-F135 PolarHBondContact O-N 3.12Å; L132-R136 WeakPolarHBondContact O-CB 3.48Å; L132-R136 PolarHBondContact O-N 3.48Å
133	L	98.2	Very high	95.3	Very high	32 Å²	32	34.9 Å²	34.9	17%	0.168	17%	0.17	C	C	.	.	H	α-helix	trans	-63.5	-43.4	178.7	-66.8	168.9	0	0	0	111.3	V129 T130 L131 R136 I137 M175 F178 A179 N182	V129-L133 HydrophobicContact CG1-CD1 3.99Å; V129-L133 HydrophobicContact CG1-CG 4.44Å; V129-L133 WeakPolarHBondContact O-CG 3.44Å; V129-L133 PolarHBondContact O-N 3.45Å; T130-L133 PolarHBondContact O-N 3.49Å; L131-L133 VanDerWaalsContact C-N 3.32Å; L131-L133 PolarHBondContact O-N 2.97Å; L133-R136 PolarHBondContact O-N 2.93Å; L133-I137 WeakPolarHBondContact O-CG1 3.39Å; L133-I137 PolarHBondContact O-N 3.41Å; L133-M175 HydrophobicContact CD1-CG 4.16Å; L133-M175 WeakPolarHBondContact CD1-O 3.21Å; L133-F178 HydrophobicContact CB-CB 3.82Å; L133-F178 HydrophobicContact CD1-CB 4.28Å; L133-A179 HydrophobicContact CD1-CB 3.97Å; L133-A179 HydrophobicContact CD2-CB 4.33Å; L133-N182 PolarHBondContact O-ND2 3.25Å
134	V	96.9	Very high	94.8	Very high	2 Å²	2	34.9 Å²	34.9	1%	0.012	17%	0.17	C	C	.	.	H	α-helix	trans	-64.5	-47.1	176.9	169.6	0	0	0	0	110.9	T130 L131 R136 I137 Y138 F178 H364	T130-V134 HydrophobicContact CG2-CG2 4.33Å; T130-V134 WeakPolarHBondContact O-CB 3.48Å; T130-V134 VanDerWaalsContact O-CG2 3.26Å; T130-V134 WeakPolarHBondContact O-CG2 3.49Å; T130-V134 PolarHBondContact O-N 2.84Å; L131-V134 PolarHBondContact O-N 2.88Å; V134-R136 VanDerWaalsContact C-N 3.32Å; V134-R136 PolarHBondContact O-N 3.24Å; V134-I137 WeakPolarHBondContact O-CB 3.35Å; V134-I137 PolarHBondContact O-N 2.94Å; V134-Y138 HydrophobicContact CG1-CD2 3.64Å; V134-Y138 HydrophobicContact CG1-CE2 3.4Å; V134-Y138 VanDerWaalsContact CG1-CE2 3.4Å; V134-Y138 WeakPolarHBondContact O-CD2 3.46Å; V134-Y138 PolarHBondContact O-N 3.45Å; V134-F178 HydrophobicContact CG2-CD1 3.99Å; V134-F178 HydrophobicContact CG2-CD2 3.75Å; V134-F178 HydrophobicContact CG2-CE1 4.05Å; V134-F178 HydrophobicContact CG2-CE2 3.81Å; V134-F178 HydrophobicContact CG2-CG 3.86Å; V134-F178 HydrophobicContact CG2-CZ 3.97Å; V134-H364 HydrophobicContact CG1-CB 4.11Å; V134-H364 HydrophobicContact CG2-CB 3.87Å
135	F	95.6	Very high	94.4	Very high	6 Å²	6	35.1 Å²	35.1	3%	0.026	17%	0.171	C	C	.	.	H	α-helix	trans	-63	-37.4	177.5	-69.4	-30.8	0	0	0	113	V41 L44 W45 L131 L132 I137 Y138 N139 F149 C153	V41-F135 HydrophobicContact CB-CB 4.06Å; V41-F135 HydrophobicContact CB-CD1 3.95Å; V41-F135 HydrophobicContact CB-CD2 3.67Å; V41-F135 HydrophobicContact CB-CE1 4.18Å; V41-F135 HydrophobicContact CB-CE2 3.89Å; V41-F135 HydrophobicContact CB-CG 3.66Å; V41-F135 HydrophobicContact CB-CZ 4.09Å; V41-F135 HydrophobicContact CG1-CB 4.12Å; V41-F135 HydrophobicContact CG1-CD1 3.54Å; V41-F135 HydrophobicContact CG1-CD2 4.23Å; V41-F135 HydrophobicContact CG1-CE1 3.82Å; V41-F135 HydrophobicContact CG1-CE2 4.44Å; V41-F135 HydrophobicContact CG1-CG 3.73Å; V41-F135 HydrophobicContact CG1-CZ 4.21Å; V41-F135 HydrophobicContact CG2-CB 4.2Å; V41-F135 HydrophobicContact CG2-CD2 4.38Å; V41-F135 HydrophobicContact CG2-CG 4.32Å; L44-F135 HydrophobicContact CB-CZ 4.43Å; W45-F135 HydrophobicContact CB-CE2 4.12Å; L131-F135 HydrophobicContact CB-CD2 4.43Å; L131-F135 HydrophobicContact CB-CE2 4.22Å; L131-F135 WeakPolarHBondContact O-CB 3.47Å; L131-F135 VanDerWaalsContact O-CD2 3.25Å; L131-F135 WeakPolarHBondContact O-CD2 3.29Å; L131-F135 WeakPolarHBondContact O-CG 3.44Å; L131-F135 PolarHBondContact O-N 2.71Å; L132-F135 PolarHBondContact O-N 3.12Å; F135-I137 VanDerWaalsContact C-N 3.32Å; F135-I137 PolarHBondContact O-N 2.91Å; F135-Y138 PolarHBondContact O-N 3.48Å; F135-N139 VanDerWaalsContact O-CB 3.29Å; F135-N139 WeakPolarHBondContact O-CB 3.41Å; F135-N139 PolarHBondContact O-N 3.07Å; F135-F149 HydrophobicContact CE1-CB 4.09Å; F135-F149 HydrophobicContact CE1-CD1 4.43Å; F135-F149 HydrophobicContact CE1-CG 4.27Å; F135-C153 WeakPolarHBondContact CZ-SG 3.41Å
136	R	95.9	Very high	94	Very high	99 Å²	99	31.2 Å²	31.2	37%	0.374	15%	0.147	S	C	.	.	H	α-helix	trans	-60.3	-43.7	174	-173.9	173.4	-179.1	-101	5	111.2	L132 L133 V134 N139 R140 N182 D186	L132-R136 WeakPolarHBondContact O-CB 3.48Å; L132-R136 PolarHBondContact O-N 3.48Å; L133-R136 PolarHBondContact O-N 2.93Å; V134-R136 VanDerWaalsContact C-N 3.32Å; V134-R136 PolarHBondContact O-N 3.24Å; R136-N139 PolarHBondContact O-N 2.69Å; R136-R140 WeakPolarHBondContact O-CB 3.33Å; R136-R140 VanDerWaalsContact O-CG 3.31Å; R136-R140 WeakPolarHBondContact O-CG 3.48Å; R136-R140 PolarHBondContact O-N 2.94Å; R136-N182 WeakPolarHBondContact CD-OD1 3.27Å; R136-N182 VanDerWaalsContact CG-OD1 3.24Å; R136-N182 WeakPolarHBondContact CG-OD1 3.29Å; R136-N182 PolarHBondContact NH1-O 3.39Å; R136-N182 PolarHBondContact NH1-OD1 3.07Å; R136-D186 IonicContact CZ-OD1 3.84Å; R136-D186 IonicContact CZ-OD2 2.8Å; R136-D186 VanDerWaalsContact CZ-OD2 3.23Å; R136-D186 IonicContact NH1-OD1 2.66Å; R136-D186 IonicContact NH1-OD2 3.61Å; R136-D186 PolarHBondContact NH1-OD2 3.29Å; R136-D186 IonicContact NH2-OD1 2.79Å; R136-D186 PolarHBondContact NH2-OD1 3.4Å; R136-D186 IonicContact NH2-OD2 2.65Å; R136-D186 PolarHBondContact NH2-OD2 3.21Å
137	I	95.9	Very high	93.5	Very high	2 Å²	2	31.1 Å²	31.1	1%	0.01	15%	0.146	C	C	.	.	H	α-helix	trans	-59.4	-47.3	174.9	-68	162.5	0	0	0	110.9	L133 V134 F135 R140 T141 F178 T181 L185 V337 F341	L133-I137 WeakPolarHBondContact O-CG1 3.39Å; L133-I137 PolarHBondContact O-N 3.41Å; V134-I137 WeakPolarHBondContact O-CB 3.35Å; V134-I137 PolarHBondContact O-N 2.94Å; F135-I137 VanDerWaalsContact C-N 3.32Å; F135-I137 PolarHBondContact O-N 2.91Å; I137-R140 PolarHBondContact O-N 3.04Å; I137-T141 HydrophobicContact CG2-CG2 4.48Å; I137-T141 WeakPolarHBondContact O-CB 3.45Å; I137-T141 WeakPolarHBondContact O-CG2 3.28Å; I137-T141 PolarHBondContact O-N 3Å; I137-T141 PolarHBondContact O-OG1 3.19Å; I137-F178 HydrophobicContact CD1-CB 4.48Å; I137-F178 HydrophobicContact CD1-CD1 3.82Å; I137-T181 HydrophobicContact CD1-CG2 3.75Å; I137-T181 HydrophobicContact CG1-CG2 4.26Å; I137-L185 HydrophobicContact CB-CD1 4.49Å; I137-L185 HydrophobicContact CG1-CD1 3.99Å; I137-L185 HydrophobicContact CG2-CD1 4.38Å; I137-V337 HydrophobicContact CG2-CG1 3.88Å; I137-V337 HydrophobicContact CG2-CG2 3.9Å; I137-F341 HydrophobicContact CG2-CZ 4.43Å
138	Y	93.9	Very high	93	Very high	2 Å²	2	31.1 Å²	31.1	1%	0.008	15%	0.146	C	C	.	.	H	α-helix	trans	-65.1	-41.2	178.9	-78.9	-66.3	0	0	0	113.2	V134 F135 R140 T141 K142 V144 F149 H364 P367 Y368	V134-Y138 HydrophobicContact CG1-CD2 3.64Å; V134-Y138 HydrophobicContact CG1-CE2 3.4Å; V134-Y138 VanDerWaalsContact CG1-CE2 3.4Å; V134-Y138 WeakPolarHBondContact O-CD2 3.46Å; V134-Y138 PolarHBondContact O-N 3.45Å; F135-Y138 PolarHBondContact O-N 3.48Å; Y138-R140 VanDerWaalsContact C-N 3.31Å; Y138-R140 PolarHBondContact O-N 3.42Å; Y138-T141 PolarHBondContact O-OG1 3.32Å; Y138-K142 PolarHBondContact O-N 3.49Å; Y138-V144 HydrophobicContact CD1-CB 3.77Å; Y138-V144 HydrophobicContact CD1-CG2 3.61Å; Y138-V144 HydrophobicContact CE1-CB 3.92Å; Y138-V144 HydrophobicContact CE1-CG1 4.4Å; Y138-V144 HydrophobicContact CE1-CG2 3.38Å; Y138-F149 AromaticContact CD1-CE1 3.76Å; Y138-F149 HydrophobicContact CD1-CE1 3.76Å; Y138-F149 HydrophobicContact CD1-CZ 4.26Å; Y138-F149 HydrophobicContact CD2-CD1 4.38Å; Y138-F149 AromaticContact CD2-CE1 3.78Å; Y138-F149 HydrophobicContact CD2-CE1 3.78Å; Y138-F149 HydrophobicContact CE1-CE1 4.36Å; Y138-F149 HydrophobicContact CE2-CE1 4.38Å; Y138-F149 HydrophobicContact CG-CD1 4.45Å; Y138-F149 AromaticContact CG-CE1 3.45Å; Y138-F149 HydrophobicContact CG-CE1 3.45Å; Y138-F149 VanDerWaalsContact CG-CE1 3.45Å; Y138-F149 AromaticContact CG-CZ 3.96Å; Y138-F149 HydrophobicContact CG-CZ 3.96Å; Y138-H364 PolarHBondContact OH-O 3.46Å; Y138-P367 HydrophobicContact CE1-CB 4.34Å; Y138-P367 WeakPolarHBondContact OH-CB 3.32Å; Y138-Y368 HydrophobicContact CD1-CD2 4.17Å; Y138-Y368 AromaticContact CE1-CD2 3.85Å; Y138-Y368 HydrophobicContact CE1-CD2 3.85Å; Y138-Y368 HydrophobicContact CE1-CG 4.32Å; Y138-Y368 PolarHBondContact OH-N 3.22Å
139	N	91.9	Very high	92.6	Very high	50 Å²	50	30 Å²	30	27%	0.267	14%	0.14	S	C	.	.	H	α-helix	trans	-65.7	-34.7	178.7	-174.6	61.3	0	0	0	112.5	T37 F135 R136 K142	T37-N139 HydrophobicContact CG2-CB 3.95Å; F135-N139 VanDerWaalsContact O-CB 3.29Å; F135-N139 WeakPolarHBondContact O-CB 3.41Å; F135-N139 PolarHBondContact O-N 3.07Å; R136-N139 PolarHBondContact O-N 2.69Å; N139-K142 WeakPolarHBondContact O-CG 3.47Å
140	R	90.9	Very high	92.1	Very high	56 Å²	56	32.5 Å²	32.5	21%	0.211	15%	0.146	C	C	.	.	H	α-helix	trans	-71.9	-49.4	176.9	-79.9	-122.7	-77.7	-176.9	-31	112.7	R136 I137 Y138 K142 N182 L185 D186 E333	R136-R140 WeakPolarHBondContact O-CB 3.33Å; R136-R140 VanDerWaalsContact O-CG 3.31Å; R136-R140 WeakPolarHBondContact O-CG 3.48Å; R136-R140 PolarHBondContact O-N 2.94Å; I137-R140 PolarHBondContact O-N 3.04Å; Y138-R140 VanDerWaalsContact C-N 3.31Å; Y138-R140 PolarHBondContact O-N 3.42Å; R140-K142 PolarHBondContact O-N 3.2Å; R140-N182 PolarHBondContact NH2-O 3.46Å; R140-L185 VanDerWaalsContact CZ-C 3.48Å; R140-L185 PolarHBondContact NH1-O 3.08Å; R140-L185 PolarHBondContact NH2-O 3.41Å; R140-D186 IonicContact CZ-OD1 3.95Å; R140-D186 IonicContact NH1-OD1 2.72Å; R140-D186 VanDerWaalsContact NH2-CG 3.28Å; R140-D186 IonicContact NH2-OD1 3.84Å; R140-D186 PolarHBondContact NH2-OD1 2.7Å; R140-D186 IonicContact NH2-OD2 3.83Å; R140-E333 WeakPolarHBondContact CB-OE2 3.34Å; R140-E333 IonicContact CZ-OE1 2.73Å; R140-E333 IonicContact NE-OE1 3.53Å; R140-E333 IonicContact NE-OE2 2.81Å; R140-E333 VanDerWaalsContact NH1-CD 3.29Å; R140-E333 IonicContact NH1-OE1 3.05Å; R140-E333 PolarHBondContact NH1-OE1 3.28Å; R140-E333 IonicContact NH1-OE2 3.55Å
141	T	89.8	Confident	91.4	Very high	8 Å²	8	35.6 Å²	35.6	5%	0.049	16%	0.16	C	C	.	.	H	α-helix	trans	-74.7	-25.2	-176.7	55.6	0	0	0	0	113.9	I137 Y138 K143 P334 V337 Y368	I137-T141 HydrophobicContact CG2-CG2 4.48Å; I137-T141 WeakPolarHBondContact O-CB 3.45Å; I137-T141 WeakPolarHBondContact O-CG2 3.28Å; I137-T141 PolarHBondContact O-N 3Å; I137-T141 PolarHBondContact O-OG1 3.19Å; Y138-T141 PolarHBondContact O-OG1 3.32Å; T141-K143 PolarHBondContact O-N 2.86Å; T141-P334 HydrophobicContact CG2-CG 4.45Å; T141-V337 HydrophobicContact CG2-CB 4.3Å; T141-V337 HydrophobicContact CG2-CG2 3.83Å; T141-Y368 HydrophobicContact CG2-CE2 3.86Å; T141-Y368 WeakPolarHBondContact OG1-CE2 3.35Å
142	K	88.9	Confident	90.7	Very high	120 Å²	120	35.8 Å²	35.8	52%	0.522	16%	0.161	S	C	.	.			trans	48.2	32.8	179.6	-59.8	-177.8	179.6	175.3	0	113.7	T34 Y138 N139 R140	T34-K142 HydrophobicContact CG2-CB 4.41Å; T34-K142 WeakPolarHBondContact CG2-O 3.35Å; Y138-K142 PolarHBondContact O-N 3.49Å; N139-K142 WeakPolarHBondContact O-CG 3.47Å; R140-K142 PolarHBondContact O-N 3.2Å
143	K	86.9	Confident	90	Very high	62 Å²	62	31.7 Å²	31.7	27%	0.27	14%	0.14	S	C	.	.			trans	-90.6	-26.6	179	-66.7	-63.1	-177.9	-176.3	0	113.1	T141 D331 P334 Y368	T141-K143 PolarHBondContact O-N 2.86Å; K143-D331 IonicContact NZ-OD1 2.74Å; K143-D331 PolarHBondContact NZ-OD1 3.47Å; K143-P334 HydrophobicContact CD-CB 4.49Å; K143-P334 HydrophobicContact CG-CB 4.33Å; K143-Y368 HydrophobicContact CB-CE2 4.14Å; K143-Y368 HydrophobicContact CG-CE2 4.17Å
144	V	88.8	Confident	88.6	Confident	0 Å²	0	32.5 Å²	32.5	0%	0	15%	0.147	C	C	.	.	S	Bend	trans	-110	129.6	-172.9	-175.6	0	0	0	0	110.5	Y138 V148 F149 P367 Y368 W371	Y138-V144 HydrophobicContact CD1-CB 3.77Å; Y138-V144 HydrophobicContact CD1-CG2 3.61Å; Y138-V144 HydrophobicContact CE1-CB 3.92Å; Y138-V144 HydrophobicContact CE1-CG1 4.4Å; Y138-V144 HydrophobicContact CE1-CG2 3.38Å; V144-V148 HydrophobicContact CG1-CB 3.65Å; V144-V148 HydrophobicContact CG1-CG1 3.91Å; V144-V148 HydrophobicContact CG1-CG2 3.92Å; V144-F149 HydrophobicContact CB-CE1 4.26Å; V144-F149 HydrophobicContact CB-CZ 4.33Å; V144-F149 HydrophobicContact CG1-CE1 4.08Å; V144-F149 HydrophobicContact CG1-CZ 4.42Å; V144-P367 HydrophobicContact CG1-CB 4.2Å; V144-Y368 HydrophobicContact CG2-CD2 4.49Å; V144-W371 HydrophobicContact CG1-CD2 4.39Å; V144-W371 HydrophobicContact CG1-CG 4.45Å; V144-W371 HydrophobicContact CG2-CB 3.87Å; V144-W371 HydrophobicContact CG2-CG 4.37Å
145	P	89	Confident	87.2	Confident	14 Å²	14	34.4 Å²	34.4	9%	0.091	16%	0.163	C	C	.	.			trans	-71.2	147.1	179.7	25.8	-29.8	0	0	0	111.7	F32 Y147 V148 W371	F32-P145 WeakPolarHBondContact O-CB 3.45Å; P145-Y147 VanDerWaalsContact C-N 3.33Å; P145-Y147 HydrophobicContact CB-CD1 3.86Å; P145-Y147 HydrophobicContact CB-CE1 3.77Å; P145-Y147 HydrophobicContact CG-CD1 3.94Å; P145-Y147 HydrophobicContact CG-CE1 3.4Å; P145-Y147 VanDerWaalsContact CG-CE1 3.4Å; P145-Y147 PolarHBondContact O-N 2.91Å; P145-Y147 VanDerWaalsContact O-N 3.17Å; P145-V148 HydrophobicContact CG-CG2 3.85Å; P145-V148 WeakPolarHBondContact O-CB 3.26Å; P145-V148 WeakPolarHBondContact O-CG2 3.46Å; P145-V148 PolarHBondContact O-N 3.44Å; P145-V148 VanDerWaalsContact O-N 3.12Å; P145-W371 VanDerWaalsContact CG-NE1 3.3Å
146	P	89.1	Confident	86.1	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	16%	0.162	C	C	.	.	G	3₁₀ helix	trans	-57.5	-33.4	-170.3	-28.3	34.6	0	0	0	117	L31 K33 V40 V148 F149	L31-P146 WeakPolarHBondContact O-CD 3.38Å; K33-P146 VanDerWaalsContact O-CG 3.24Å; K33-P146 WeakPolarHBondContact O-CG 3.27Å; V40-P146 HydrophobicContact CB-CB 3.91Å; V40-P146 HydrophobicContact CG1-CB 4.04Å; V40-P146 HydrophobicContact CG2-CB 3.73Å; P146-V148 PolarHBondContact O-N 3.42Å; P146-F149 HydrophobicContact CB-CD2 4.29Å; P146-F149 HydrophobicContact CB-CE2 4.31Å; P146-F149 WeakPolarHBondContact O-CB 3.49Å; P146-F149 VanDerWaalsContact O-CD2 3.26Å; P146-F149 WeakPolarHBondContact O-CD2 3.45Å; P146-F149 PolarHBondContact O-N 2.96Å; P146-F149 VanDerWaalsContact O-N 3.07Å
147	Y	87.5	Confident	85.5	Confident	35 Å²	35	36.2 Å²	36.2	14%	0.137	17%	0.171	C	C	.	.	G	3₁₀ helix	trans	-58.3	-25.4	179.7	75.8	-95.8	0	0	0	113	L31 F32 P145 F149 F150 F151 W371 H380 V384	L31-Y147 WeakPolarHBondContact O-CB 3.25Å; L31-Y147 WeakPolarHBondContact O-CD1 3.47Å; L31-Y147 PolarHBondContact O-N 2.8Å; F32-Y147 AromaticContact CD1-CD1 3.6Å; F32-Y147 HydrophobicContact CD1-CD1 3.6Å; F32-Y147 AromaticContact CD1-CE1 3.68Å; F32-Y147 HydrophobicContact CD1-CE1 3.68Å; F32-Y147 AromaticContact CE1-CD1 3.67Å; F32-Y147 HydrophobicContact CE1-CD1 3.67Å; F32-Y147 AromaticContact CE1-CE1 3.74Å; F32-Y147 HydrophobicContact CE1-CE1 3.74Å; F32-Y147 HydrophobicContact CE1-CG 4.42Å; P145-Y147 VanDerWaalsContact C-N 3.33Å; P145-Y147 HydrophobicContact CB-CD1 3.86Å; P145-Y147 HydrophobicContact CB-CE1 3.77Å; P145-Y147 HydrophobicContact CG-CD1 3.94Å; P145-Y147 HydrophobicContact CG-CE1 3.4Å; P145-Y147 VanDerWaalsContact CG-CE1 3.4Å; P145-Y147 PolarHBondContact O-N 2.91Å; P145-Y147 VanDerWaalsContact O-N 3.17Å; Y147-F149 PolarHBondContact O-N 3.4Å; Y147-F150 WeakPolarHBondContact O-CB 3.43Å; Y147-F150 PolarHBondContact O-N 3.15Å; Y147-F151 HydrophobicContact CD2-CE2 4.19Å; Y147-F151 HydrophobicContact CE2-CE2 4.43Å; Y147-W371 HydrophobicContact CE2-CZ2 4.39Å; Y147-W371 WeakPolarHBondContact OH-CZ2 3.16Å; Y147-H380 PolarHBondContact OH-ND1 2.91Å; Y147-V384 HydrophobicContact CE2-CG2 4.08Å
148	V	88.5	Confident	85.3	Confident	0 Å²	0	37.2 Å²	37.2	0%	0	18%	0.175	C	C	.	.	G	3₁₀ helix	trans	-70.6	-26.7	-177.4	-174.6	0	0	0	0	111.2	V144 P145 P146 F150 F151 V152 P367 W371 L387	V144-V148 HydrophobicContact CG1-CB 3.65Å; V144-V148 HydrophobicContact CG1-CG1 3.91Å; V144-V148 HydrophobicContact CG1-CG2 3.92Å; P145-V148 HydrophobicContact CG-CG2 3.85Å; P145-V148 WeakPolarHBondContact O-CB 3.26Å; P145-V148 WeakPolarHBondContact O-CG2 3.46Å; P145-V148 PolarHBondContact O-N 3.44Å; P145-V148 VanDerWaalsContact O-N 3.12Å; P146-V148 PolarHBondContact O-N 3.42Å; V148-F150 PolarHBondContact O-N 2.97Å; V148-F151 WeakPolarHBondContact O-CB 3.47Å; V148-F151 PolarHBondContact O-N 3.2Å; V148-V152 PolarHBondContact O-N 2.74Å; V148-P367 HydrophobicContact CG1-CB 3.73Å; V148-P367 HydrophobicContact CG1-CG 4.18Å; V148-W371 HydrophobicContact CB-CH2 4.36Å; V148-W371 HydrophobicContact CB-CZ2 4.48Å; V148-W371 HydrophobicContact CG1-CE3 4.48Å; V148-W371 HydrophobicContact CG1-CH2 3.81Å; V148-W371 HydrophobicContact CG1-CZ2 4.38Å; V148-W371 HydrophobicContact CG1-CZ3 3.88Å; V148-W371 HydrophobicContact CG2-CD2 4.44Å; V148-W371 HydrophobicContact CG2-CH2 3.51Å; V148-W371 HydrophobicContact CG2-CZ2 3.25Å; V148-W371 HydrophobicContact CG2-CZ3 4.22Å; V148-L387 HydrophobicContact CG1-CD1 4.22Å
149	F	88.9	Confident	85.3	Confident	0 Å²	0	37.1 Å²	37.1	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-64.5	-23.3	178.2	-55.3	-41.1	0	0	0	112.5	T37 V41 L44 F135 Y138 V144 P146 Y147 F151 V152 C153	T37-F149 HydrophobicContact CG2-CD2 4.43Å; T37-F149 HydrophobicContact CG2-CE2 3.51Å; T37-F149 HydrophobicContact CG2-CZ 4.05Å; V41-F149 HydrophobicContact CG1-CB 4.46Å; V41-F149 HydrophobicContact CG1-CD2 3.47Å; V41-F149 VanDerWaalsContact CG1-CD2 3.47Å; V41-F149 HydrophobicContact CG1-CE2 3.91Å; V41-F149 HydrophobicContact CG1-CG 4Å; L44-F149 HydrophobicContact CD1-CB 3.6Å; F135-F149 HydrophobicContact CE1-CB 4.09Å; F135-F149 HydrophobicContact CE1-CD1 4.43Å; F135-F149 HydrophobicContact CE1-CG 4.27Å; Y138-F149 AromaticContact CD1-CE1 3.76Å; Y138-F149 HydrophobicContact CD1-CE1 3.76Å; Y138-F149 HydrophobicContact CD1-CZ 4.26Å; Y138-F149 HydrophobicContact CD2-CD1 4.38Å; Y138-F149 AromaticContact CD2-CE1 3.78Å; Y138-F149 HydrophobicContact CD2-CE1 3.78Å; Y138-F149 HydrophobicContact CE1-CE1 4.36Å; Y138-F149 HydrophobicContact CE2-CE1 4.38Å; Y138-F149 HydrophobicContact CG-CD1 4.45Å; Y138-F149 AromaticContact CG-CE1 3.45Å; Y138-F149 HydrophobicContact CG-CE1 3.45Å; Y138-F149 VanDerWaalsContact CG-CE1 3.45Å; Y138-F149 AromaticContact CG-CZ 3.96Å; Y138-F149 HydrophobicContact CG-CZ 3.96Å; V144-F149 HydrophobicContact CB-CE1 4.26Å; V144-F149 HydrophobicContact CB-CZ 4.33Å; V144-F149 HydrophobicContact CG1-CE1 4.08Å; V144-F149 HydrophobicContact CG1-CZ 4.42Å; P146-F149 HydrophobicContact CB-CD2 4.29Å; P146-F149 HydrophobicContact CB-CE2 4.31Å; P146-F149 WeakPolarHBondContact O-CB 3.49Å; P146-F149 VanDerWaalsContact O-CD2 3.26Å; P146-F149 WeakPolarHBondContact O-CD2 3.45Å; P146-F149 PolarHBondContact O-N 2.96Å; P146-F149 VanDerWaalsContact O-N 3.07Å; Y147-F149 PolarHBondContact O-N 3.4Å; F149-F151 VanDerWaalsContact C-N 3.28Å; F149-F151 PolarHBondContact O-N 3.22Å; F149-V152 PolarHBondContact O-N 2.88Å; F149-C153 PolarHBondContact O-N 3.27Å; F149-C153 PolarHBondContact O-SG 2.91Å
150	F	86.8	Confident	85.4	Confident	110 Å²	110	35.3 Å²	35.3	48%	0.482	16%	0.164	S	C	.	.	H	α-helix	trans	-57.6	-41.6	169.2	179.6	-98.1	0	0	0	111.7	L44 Y147 V148 C153 C154	L44-F150 HydrophobicContact CD2-CD2 4.45Å; Y147-F150 WeakPolarHBondContact O-CB 3.43Å; Y147-F150 PolarHBondContact O-N 3.15Å; V148-F150 PolarHBondContact O-N 2.97Å; F150-C153 PolarHBondContact O-N 3.06Å; F150-C154 HydrophobicContact CD2-CB 4.08Å; F150-C154 HydrophobicContact CE1-CB 4.36Å; F150-C154 HydrophobicContact CE2-CB 3.74Å; F150-C154 HydrophobicContact CZ-CB 3.89Å; F150-C154 WeakPolarHBondContact O-CB 3.12Å; F150-C154 PolarHBondContact O-N 2.75Å
151	F	82.8	Confident	85.5	Confident	65 Å²	65	32.7 Å²	32.7	29%	0.285	15%	0.154	S	C	.	.	H	α-helix	trans	-72.6	-30.3	177.7	-58.5	-72.6	0	0	0	112.7	Y147 V148 F149 C153 A155 V384	Y147-F151 HydrophobicContact CD2-CE2 4.19Å; Y147-F151 HydrophobicContact CE2-CE2 4.43Å; V148-F151 WeakPolarHBondContact O-CB 3.47Å; V148-F151 PolarHBondContact O-N 3.2Å; F149-F151 VanDerWaalsContact C-N 3.28Å; F149-F151 PolarHBondContact O-N 3.22Å; F151-C153 VanDerWaalsContact C-N 3.3Å; F151-A155 HydrophobicContact CB-CB 4.15Å; F151-A155 HydrophobicContact CD1-CB 4.02Å; F151-A155 WeakPolarHBondContact O-CB 3.27Å; F151-V384 HydrophobicContact CE1-CG1 4.24Å; F151-V384 HydrophobicContact CE2-CG1 4.05Å; F151-V384 HydrophobicContact CE2-CG2 4.21Å; F151-V384 HydrophobicContact CZ-CG1 3.74Å
152	V	81.4	Confident	85.8	Confident	3 Å²	3	32.4 Å²	32.4	2%	0.018	15%	0.153	C	C	.	.	H	α-helix	trans	-67.5	-33.9	175.9	-179.7	0	0	0	0	111.5	L131 V148 F149 F363 P367	L131-V152 HydrophobicContact CD2-CG1 4.49Å; V148-V152 PolarHBondContact O-N 2.74Å; F149-V152 PolarHBondContact O-N 2.88Å; V152-F363 HydrophobicContact CG1-CE1 4.28Å; V152-F363 VanDerWaalsContact O-CE1 3.25Å; V152-F363 WeakPolarHBondContact O-CE1 3.3Å; V152-F363 WeakPolarHBondContact O-CZ 3.44Å; V152-P367 HydrophobicContact CG2-CG 3.57Å
153	C	81.8	Confident	86.1	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-95.2	-61.2	-176	-55.1	0	0	0	0	111	E48 F135 F149 F150 F151 H160	E48-C153 HydrophobicContact CG-CB 3.89Å; E48-C153 VanDerWaalsContact OE1-C 3.26Å; E48-C153 VanDerWaalsContact OE1-CB 3.24Å; E48-C153 WeakPolarHBondContact OE1-CB 3.47Å; F135-C153 WeakPolarHBondContact CZ-SG 3.41Å; F149-C153 PolarHBondContact O-N 3.27Å; F149-C153 PolarHBondContact O-SG 2.91Å; F150-C153 PolarHBondContact O-N 3.06Å; F151-C153 VanDerWaalsContact C-N 3.3Å; C153-H160 PolarHBondContact O-CE1 2.85Å
154	C	69.4	Low	86.6	Confident	48 Å²	48	23.7 Å²	23.7	32%	0.324	12%	0.115	S	C	.	.	T	Hydrogen-bonded Turn	trans	-88.6	-19.8	-165.1	-52.6	0	0	0	0	113.5	F150	F150-C154 HydrophobicContact CD2-CB 4.08Å; F150-C154 HydrophobicContact CE1-CB 4.36Å; F150-C154 HydrophobicContact CE2-CB 3.74Å; F150-C154 HydrophobicContact CZ-CB 3.89Å; F150-C154 WeakPolarHBondContact O-CB 3.12Å; F150-C154 PolarHBondContact O-N 2.75Å
155	A	66.4	Low	86.9	Confident	43 Å²	43	23.9 Å²	23.9	36%	0.355	12%	0.116	S	C	.	.	T	Hydrogen-bonded Turn	trans	-90	-9.5	-171.9	0	0	0	0	0	114.7	F151	F151-A155 HydrophobicContact CB-CB 4.15Å; F151-A155 HydrophobicContact CD1-CB 4.02Å; F151-A155 WeakPolarHBondContact O-CB 3.27Å
156	S	72.9	Confident	87.2	Confident	1 Å²	1	25.4 Å²	25.4	1%	0.007	12%	0.12	C	C	.	.			trans	-109	91	179.5	-161.2	0	0	0	0	114.6	R158 I159 H160 F363 E391	S156-R158 PolarHBondContact O-N 3.45Å; S156-R158 PolarHBondContact OG-N 3.39Å; S156-I159 PolarHBondContact O-N 3.26Å; S156-I159 WeakPolarHBondContact OG-CG1 3.44Å; S156-I159 PolarHBondContact OG-N 3.11Å; S156-H160 PolarHBondContact O-N 3.04Å; S156-H160 PolarHBondContact O-ND1 3.31Å; S156-F363 VanDerWaalsContact CB-CZ 3.48Å; S156-E391 WeakPolarHBondContact CA-OE1 3.41Å; S156-E391 WeakPolarHBondContact CB-OE1 3.5Å; S156-E391 PolarHBondContact OG-OE1 3.31Å; S156-E391 PolarHBondContact OG-OE2 3.02Å
157	Y	83.9	Confident	87.6	Confident	142 Å²	142	25.4 Å²	25.4	56%	0.557	12%	0.12	S	C	*	.	H	α-helix	trans	-50.1	-39	161.8	168	-99.4	0	0	0	111.7	S161	Y157-S161 WeakPolarHBondContact O-CB 3.21Å; Y157-S161 PolarHBondContact O-N 2.99Å
158	R	91.2	Very high	88	Confident	22 Å²	22	24 Å²	24	8%	0.083	11%	0.114	C	C	.	.	H	α-helix	trans	-69.3	-41.9	-175.4	-173.5	159.4	-70.4	-101	-0.3	113.3	S156 S161 I162 Y359 W394 N395	S156-R158 PolarHBondContact O-N 3.45Å; S156-R158 PolarHBondContact OG-N 3.39Å; R158-S161 WeakPolarHBondContact O-CB 3.43Å; R158-S161 PolarHBondContact O-N 2.93Å; R158-I162 HydrophobicContact CG-CD1 3.86Å; R158-I162 HydrophobicContact CG-CG1 4.4Å; R158-I162 WeakPolarHBondContact O-CB 3.43Å; R158-I162 VanDerWaalsContact O-CG1 3.3Å; R158-I162 WeakPolarHBondContact O-CG1 3.31Å; R158-I162 PolarHBondContact O-N 3.46Å; R158-Y359 HydrophobicContact CB-CD1 4.12Å; R158-Y359 HydrophobicContact CB-CE1 4.45Å; R158-Y359 HydrophobicContact CG-CD1 3.96Å; R158-W394 PolarHBondContact NE-O 3.32Å; R158-W394 PolarHBondContact NH1-O 2.89Å; R158-W394 PolarHBondContact NH2-O 3.18Å; R158-N395 PolarHBondContact NE-OD1 3.5Å
159	I	94.1	Very high	88.4	Confident	1 Å²	1	24 Å²	24	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-63.8	-45.8	178.3	-63.7	-54.9	0	0	0	110.5	Y127 S156 S161 I162 F163 Y359 V360 F363	Y127-I159 HydrophobicContact CD2-CG2 4.21Å; Y127-I159 HydrophobicContact CE2-CG2 3.75Å; S156-I159 PolarHBondContact O-N 3.26Å; S156-I159 WeakPolarHBondContact OG-CG1 3.44Å; S156-I159 PolarHBondContact OG-N 3.11Å; I159-S161 VanDerWaalsContact C-N 3.25Å; I159-S161 PolarHBondContact O-N 2.83Å; I159-I162 HydrophobicContact CD1-CD1 4.29Å; I159-I162 PolarHBondContact O-N 3.43Å; I159-F163 HydrophobicContact CG2-CD2 3.92Å; I159-F163 HydrophobicContact CG2-CE2 3.92Å; I159-F163 WeakPolarHBondContact O-CD2 3.44Å; I159-F163 PolarHBondContact O-N 3.33Å; I159-Y359 HydrophobicContact CD1-CD1 3.84Å; I159-Y359 HydrophobicContact CD1-CE1 4.38Å; I159-Y359 HydrophobicContact CD1-CG 4.36Å; I159-Y359 HydrophobicContact CG1-CD1 4.37Å; I159-Y359 HydrophobicContact CG1-CE1 4.49Å; I159-V360 HydrophobicContact CD1-CB 4.05Å; I159-V360 HydrophobicContact CD1-CG2 4.26Å; I159-F363 HydrophobicContact CD1-CB 3.83Å; I159-F363 HydrophobicContact CD1-CD1 3.93Å; I159-F363 HydrophobicContact CD1-CG 3.85Å; I159-F363 HydrophobicContact CG1-CB 4.29Å; I159-F363 HydrophobicContact CG1-CD1 3.49Å; I159-F363 VanDerWaalsContact CG1-CD1 3.49Å; I159-F363 HydrophobicContact CG1-CD2 4.24Å; I159-F363 HydrophobicContact CG1-CE1 3.74Å; I159-F363 HydrophobicContact CG1-CE2 4.44Å; I159-F363 HydrophobicContact CG1-CG 3.73Å; I159-F363 HydrophobicContact CG1-CZ 4.2Å
160	H	93.5	Very high	88.8	Confident	11 Å²	11	24 Å²	24	5%	0.051	11%	0.114	C	C	.	.	H	α-helix	trans	-53.5	-47.6	171.5	-72	89.2	0	0	0	111.2	E48 I51 Y127 C153 S156 I162 F163 V164	E48-H160 IonicContact OE2-CE1 3.4Å; E48-H160 IonicContact OE2-NE2 3.51Å; E48-H160 PolarHBondContact OE2-NE2 2.92Å; I51-H160 WeakPolarHBondContact CG2-NE2 3.21Å; Y127-H160 AromaticContact CZ-NE2 3.93Å; Y127-H160 PolarHBondContact OH-CE1 3.09Å; C153-H160 PolarHBondContact O-CE1 2.85Å; S156-H160 PolarHBondContact O-N 3.04Å; S156-H160 PolarHBondContact O-ND1 3.31Å; H160-I162 PolarHBondContact O-N 2.97Å; H160-F163 PolarHBondContact O-N 3.29Å; H160-V164 WeakPolarHBondContact O-CG2 3.48Å; H160-V164 PolarHBondContact O-N 3.09Å
161	S	94.4	Very high	89.3	Confident	1 Å²	1	18.7 Å²	18.7	1%	0.007	9%	0.091	C	C	.	.	I	π-helix	trans	-64.4	-38.2	-178.8	-163.9	0	0	0	0	113	Y157 R158 I159 L165 R166	Y157-S161 WeakPolarHBondContact O-CB 3.21Å; Y157-S161 PolarHBondContact O-N 2.99Å; R158-S161 WeakPolarHBondContact O-CB 3.43Å; R158-S161 PolarHBondContact O-N 2.93Å; I159-S161 VanDerWaalsContact C-N 3.25Å; I159-S161 PolarHBondContact O-N 2.83Å; S161-L165 CarbonylContact O-C 3.49Å; S161-L165 WeakPolarHBondContact O-CA 3.21Å; S161-L165 WeakPolarHBondContact O-CB 3.44Å; S161-L165 PolarHBondContact O-N 3.37Å; S161-R166 VanDerWaalsContact CB-NH1 3.27Å; S161-R166 WeakPolarHBondContact O-CB 3.25Å; S161-R166 WeakPolarHBondContact O-CG 3.15Å; S161-R166 PolarHBondContact O-N 3.42Å; S161-R166 PolarHBondContact OG-NH1 3.08Å
162	I	95.7	Very high	90.1	Very high	2 Å²	2	15.8 Å²	15.8	1%	0.01	8%	0.078	C	C	.	.	I	π-helix	trans	-62.9	-44.3	175.1	-75.4	164.8	0	0	0	111.5	R158 I159 H160 L167 F168 P171 V360	R158-I162 HydrophobicContact CG-CD1 3.86Å; R158-I162 HydrophobicContact CG-CG1 4.4Å; R158-I162 WeakPolarHBondContact O-CB 3.43Å; R158-I162 VanDerWaalsContact O-CG1 3.3Å; R158-I162 WeakPolarHBondContact O-CG1 3.31Å; R158-I162 PolarHBondContact O-N 3.46Å; I159-I162 HydrophobicContact CD1-CD1 4.29Å; I159-I162 PolarHBondContact O-N 3.43Å; H160-I162 PolarHBondContact O-N 2.97Å; I162-L167 PolarHBondContact O-N 3.14Å; I162-F168 HydrophobicContact CB-CD2 4.4Å; I162-F168 HydrophobicContact CG1-CD2 4.3Å; I162-F168 HydrophobicContact CG2-CB 4.44Å; I162-F168 HydrophobicContact CG2-CD2 4.11Å; I162-F168 PolarHBondContact O-N 3.1Å; I162-P171 HydrophobicContact CG2-CG 3.61Å; I162-V360 HydrophobicContact CD1-CB 4.49Å; I162-V360 HydrophobicContact CG2-CB 4.32Å; I162-V360 HydrophobicContact CG2-CG1 4.35Å
163	F	96.1	Very high	90.9	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.078	C	C	.	.	I	π-helix	trans	-74.9	-65.5	179.1	-82.7	-105.1	0	0	0	111.6	F123 F126 Y127 T130 I159 H160 L167 P171 V360	F123-F163 WeakPolarHBondContact CB-O 3.49Å; F123-F163 VanDerWaalsContact CD1-O 3.23Å; F123-F163 WeakPolarHBondContact CD1-O 3.26Å; F123-F163 WeakPolarHBondContact CG-O 3.46Å; F126-F163 HydrophobicContact CB-CD1 4.45Å; F126-F163 HydrophobicContact CB-CE1 4.38Å; Y127-F163 VanDerWaalsContact CA-CE1 3.42Å; Y127-F163 VanDerWaalsContact CB-CD1 3.45Å; Y127-F163 HydrophobicContact CD2-CB 4.49Å; Y127-F163 HydrophobicContact CD2-CD1 4.18Å; Y127-F163 AromaticContact CD2-CD2 3.93Å; Y127-F163 HydrophobicContact CD2-CD2 3.93Å; Y127-F163 HydrophobicContact CD2-CE1 4.31Å; Y127-F163 HydrophobicContact CD2-CE2 4.09Å; Y127-F163 AromaticContact CD2-CG 3.96Å; Y127-F163 HydrophobicContact CD2-CG 3.96Å; Y127-F163 HydrophobicContact CD2-CZ 4.29Å; Y127-F163 HydrophobicContact CG-CD1 4.31Å; Y127-F163 HydrophobicContact CG-CG 4.36Å; T130-F163 HydrophobicContact CG2-CZ 4.3Å; I159-F163 HydrophobicContact CG2-CD2 3.92Å; I159-F163 HydrophobicContact CG2-CE2 3.92Å; I159-F163 WeakPolarHBondContact O-CD2 3.44Å; I159-F163 PolarHBondContact O-N 3.33Å; H160-F163 PolarHBondContact O-N 3.29Å; F163-L167 WeakPolarHBondContact O-CA 3.3Å; F163-L167 WeakPolarHBondContact O-CD2 3.33Å; F163-L167 PolarHBondContact O-N 3.42Å; F163-P171 HydrophobicContact CD1-CB 3.63Å; F163-P171 HydrophobicContact CD1-CG 3.97Å; F163-P171 HydrophobicContact CD2-CB 4.18Å; F163-P171 HydrophobicContact CD2-CG 3.75Å; F163-P171 HydrophobicContact CE1-CB 3.44Å; F163-P171 VanDerWaalsContact CE1-CB 3.44Å; F163-P171 HydrophobicContact CE1-CG 4.1Å; F163-P171 HydrophobicContact CE2-CB 4Å; F163-P171 HydrophobicContact CE2-CG 3.85Å; F163-P171 HydrophobicContact CG-CB 4.02Å; F163-P171 HydrophobicContact CG-CG 3.82Å; F163-P171 HydrophobicContact CZ-CB 3.63Å; F163-P171 HydrophobicContact CZ-CG 4.03Å; F163-V360 HydrophobicContact CE2-CG2 3.66Å; F163-V360 HydrophobicContact CZ-CG2 4.3Å
164	V	96.1	Very high	91.7	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.078	C	C	.	.	I	π-helix	trans	-97.9	-13.7	-163.2	-59.5	0	0	0	0	115.1	N52 V55 I56 Q120 A124 H160	N52-V164 WeakPolarHBondContact OD1-CG1 3.3Å; V55-V164 HydrophobicContact CB-CG2 4.47Å; V55-V164 HydrophobicContact CG1-CG2 3.75Å; I56-V164 HydrophobicContact CG1-CB 4.21Å; I56-V164 HydrophobicContact CG1-CG2 4.44Å; Q120-V164 VanDerWaalsContact CG-O 3.3Å; Q120-V164 WeakPolarHBondContact CG-O 3.3Å; Q120-V164 PolarHBondContact NE2-O 3.15Å; A124-V164 HydrophobicContact CB-CG1 3.85Å; H160-V164 WeakPolarHBondContact O-CG2 3.48Å; H160-V164 PolarHBondContact O-N 3.09Å
165	L	95.4	Very high	93.1	Very high	3 Å²	3	14.5 Å²	14.5	2%	0.016	7%	0.068	C	C	.	.	I	π-helix	trans	-107.7	-13.9	179.2	-58.8	177.9	0	0	0	114	V55 V59 Y61 T62 S161	V55-L165 HydrophobicContact CG1-CD1 4.05Å; V55-L165 HydrophobicContact CG1-CD2 3.94Å; V55-L165 HydrophobicContact CG1-CG 4.02Å; V59-L165 HydrophobicContact CB-CD1 4.12Å; V59-L165 HydrophobicContact CB-CD2 4.2Å; V59-L165 HydrophobicContact CG1-CD1 3.52Å; V59-L165 HydrophobicContact CG1-CD2 4.25Å; Y61-L165 WeakPolarHBondContact CD2-O 3.2Å; Y61-L165 WeakPolarHBondContact CE2-O 3.23Å; T62-L165 PolarHBondContact N-O 3.15Å; T62-L165 VanDerWaalsContact O-O 3.07Å; S161-L165 CarbonylContact O-C 3.49Å; S161-L165 WeakPolarHBondContact O-CA 3.21Å; S161-L165 WeakPolarHBondContact O-CB 3.44Å; S161-L165 PolarHBondContact O-N 3.37Å
166	R	95.8	Very high	94.6	Very high	46 Å²	46	14.2 Å²	14.2	17%	0.174	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-127.1	-18.8	-179	-65.6	-177	176.4	93.9	12.7	114.2	I64 S161 F168	I64-R166 HydrophobicContact CD1-CG 4.3Å; I64-R166 VanDerWaalsContact CD1-NE 3.35Å; S161-R166 VanDerWaalsContact CB-NH1 3.27Å; S161-R166 WeakPolarHBondContact O-CB 3.25Å; S161-R166 WeakPolarHBondContact O-CG 3.15Å; S161-R166 PolarHBondContact O-N 3.42Å; S161-R166 PolarHBondContact OG-NH1 3.08Å; R166-F168 VanDerWaalsContact C-N 3.26Å; R166-F168 HydrophobicContact CB-CD2 3.77Å; R166-F168 HydrophobicContact CB-CE1 4.48Å; R166-F168 HydrophobicContact CB-CE2 3.75Å; R166-F168 HydrophobicContact CB-CG 4.2Å; R166-F168 HydrophobicContact CB-CZ 4.12Å; R166-F168 HydrophobicContact CG-CE2 4.13Å; R166-F168 HydrophobicContact CG-CZ 4.46Å; R166-F168 PolarHBondContact O-N 3.35Å
167	L	96.8	Very high	95.8	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	6%	0.06	C	C	.	.			trans	56.5	38.2	175.3	-47.1	174.7	0	0	0	113	Y61 W66 I116 Q120 F123 I162 F163	Y61-L167 HydrophobicContact CE2-CD1 3.95Å; Y61-L167 HydrophobicContact CE2-CG 4.08Å; W66-L167 HydrophobicContact CB-CD1 4.47Å; W66-L167 HydrophobicContact CD2-CB 4.23Å; W66-L167 HydrophobicContact CD2-CD1 3.7Å; W66-L167 HydrophobicContact CE3-CB 3.58Å; W66-L167 HydrophobicContact CE3-CD1 3.77Å; W66-L167 HydrophobicContact CE3-CG 4.32Å; W66-L167 HydrophobicContact CG-CD1 4.02Å; W66-L167 HydrophobicContact CZ3-CB 4.16Å; W66-L167 HydrophobicContact CZ3-CD1 4.27Å; I116-L167 HydrophobicContact CG2-CD1 4.28Å; Q120-L167 HydrophobicContact CG-CD2 4.26Å; F123-L167 HydrophobicContact CB-CD2 3.65Å; F123-L167 HydrophobicContact CD1-CB 4.45Å; F123-L167 HydrophobicContact CD1-CD2 4.27Å; F123-L167 HydrophobicContact CD2-CB 4.04Å; F123-L167 HydrophobicContact CD2-CD2 3.48Å; F123-L167 VanDerWaalsContact CD2-CD2 3.48Å; F123-L167 HydrophobicContact CD2-CG 4.28Å; F123-L167 VanDerWaalsContact CE1-C 3.49Å; F123-L167 HydrophobicContact CE1-CB 4.29Å; F123-L167 HydrophobicContact CE2-CB 3.83Å; F123-L167 HydrophobicContact CE2-CD2 4.17Å; F123-L167 HydrophobicContact CG-CB 4.32Å; F123-L167 HydrophobicContact CG-CD2 3.51Å; F123-L167 HydrophobicContact CZ-CB 3.96Å; F123-L167 VanDerWaalsContact CZ-O 3.29Å; F123-L167 WeakPolarHBondContact CZ-O 3.5Å; I162-L167 PolarHBondContact O-N 3.14Å; F163-L167 WeakPolarHBondContact O-CA 3.3Å; F163-L167 WeakPolarHBondContact O-CD2 3.33Å; F163-L167 PolarHBondContact O-N 3.42Å
168	F	96.9	Very high	96.5	Very high	5 Å²	5	7.5 Å²	7.5	2%	0.022	3%	0.034	C	C	.	.			trans	-67.3	152.2	-176.7	-76.7	-47	0	0	0	112.9	I64 D65 Y69 F123 I162 R166 D170 P171 Q357	I64-F168 HydrophobicContact CB-CE1 4.13Å; I64-F168 HydrophobicContact CB-CZ 4.15Å; I64-F168 HydrophobicContact CD1-CZ 4.12Å; I64-F168 HydrophobicContact CG2-CE1 4.01Å; I64-F168 HydrophobicContact CG2-CZ 4.04Å; D65-F168 HydrophobicContact CB-CD1 4.01Å; D65-F168 HydrophobicContact CB-CE1 3.85Å; D65-F168 VanDerWaalsContact OD2-CE1 3.24Å; D65-F168 WeakPolarHBondContact OD2-CE1 3.44Å; Y69-F168 WeakPolarHBondContact OH-CD1 3.49Å; F123-F168 VanDerWaalsContact CE1-O 3.22Å; F123-F168 WeakPolarHBondContact CE1-O 3.42Å; I162-F168 HydrophobicContact CB-CD2 4.4Å; I162-F168 HydrophobicContact CG1-CD2 4.3Å; I162-F168 HydrophobicContact CG2-CB 4.44Å; I162-F168 HydrophobicContact CG2-CD2 4.11Å; I162-F168 PolarHBondContact O-N 3.1Å; R166-F168 VanDerWaalsContact C-N 3.26Å; R166-F168 HydrophobicContact CB-CD2 3.77Å; R166-F168 HydrophobicContact CB-CE1 4.48Å; R166-F168 HydrophobicContact CB-CE2 3.75Å; R166-F168 HydrophobicContact CB-CG 4.2Å; R166-F168 HydrophobicContact CB-CZ 4.12Å; R166-F168 HydrophobicContact CG-CE2 4.13Å; R166-F168 HydrophobicContact CG-CZ 4.46Å; R166-F168 PolarHBondContact O-N 3.35Å; F168-D170 VanDerWaalsContact C-N 3.31Å; F168-D170 PolarHBondContact O-N 2.85Å; F168-P171 VanDerWaalsContact O-CD 3.24Å; F168-P171 WeakPolarHBondContact O-CD 3.48Å; F168-P171 WeakPolarHBondContact O-CG 3.34Å; F168-Q357 HydrophobicContact CD2-CB 3.61Å; F168-Q357 HydrophobicContact CE2-CB 3.49Å; F168-Q357 VanDerWaalsContact CE2-CB 3.49Å; F168-Q357 HydrophobicContact CG-CB 4.28Å; F168-Q357 HydrophobicContact CZ-CB 4.1Å
169	N	96.8	Very high	96.9	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-71.4	-21.9	174.5	69.6	-16.8	0	0	0	114.4	Y69 Y95 F99 F103 V172 A173 V202 K203	Y69-N169 HydrophobicContact CE2-CB 4.36Å; Y69-N169 PolarHBondContact OH-N 3.34Å; Y69-N169 PolarHBondContact OH-OD1 3.23Å; Y95-N169 WeakPolarHBondContact CD1-ND2 3.31Å; Y95-N169 VanDerWaalsContact CE1-ND2 3.29Å; Y95-N169 WeakPolarHBondContact CE1-ND2 3.19Å; Y95-N169 VanDerWaalsContact CG-ND2 3.27Å; F99-N169 HydrophobicContact CD2-CB 3.64Å; F99-N169 WeakPolarHBondContact CD2-ND2 3.18Å; F99-N169 HydrophobicContact CE2-CB 3.79Å; F103-N169 HydrophobicContact CE2-CB 3.63Å; F103-N169 HydrophobicContact CZ-CB 3.67Å; N169-V172 PolarHBondContact O-N 2.83Å; N169-A173 PolarHBondContact O-N 3.44Å; N169-V202 HydrophobicContact CB-CG1 4.43Å; N169-K203 PolarHBondContact OD1-NZ 2.91Å
170	D	97.3	Very high	97.1	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-52.8	-50.6	179.2	-53.5	-105.1	0	0	0	113.2	F168 V172 A173 M174 K203 V360 W361	F168-D170 VanDerWaalsContact C-N 3.31Å; F168-D170 PolarHBondContact O-N 2.85Å; D170-V172 VanDerWaalsContact C-N 3.31Å; D170-V172 PolarHBondContact O-N 2.83Å; D170-A173 PolarHBondContact O-N 2.99Å; D170-M174 WeakPolarHBondContact O-CG 3.29Å; D170-M174 PolarHBondContact O-N 3.06Å; D170-K203 HydrophobicContact CB-CD 4.29Å; D170-K203 VanDerWaalsContact OD1-CD 3.24Å; D170-K203 WeakPolarHBondContact OD1-CD 3.09Å; D170-K203 WeakPolarHBondContact OD1-CE 3.48Å; D170-K203 IonicContact OD1-NZ 2.85Å; D170-K203 PolarHBondContact OD1-NZ 3.15Å; D170-K203 IonicContact OD2-NZ 3.44Å; D170-K203 PolarHBondContact OD2-NZ 3.5Å; D170-V360 HydrophobicContact CB-CG1 3.51Å; D170-W361 PolarHBondContact OD1-NE1 3.06Å
171	P	97.3	Very high	97.4	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-38.2	-51	165.3	-42.3	40.1	0	0	0	117	F123 I162 F163 F168 M174 M175	F123-P171 HydrophobicContact CE1-CB 4.37Å; I162-P171 HydrophobicContact CG2-CG 3.61Å; F163-P171 HydrophobicContact CD1-CB 3.63Å; F163-P171 HydrophobicContact CD1-CG 3.97Å; F163-P171 HydrophobicContact CD2-CB 4.18Å; F163-P171 HydrophobicContact CD2-CG 3.75Å; F163-P171 HydrophobicContact CE1-CB 3.44Å; F163-P171 VanDerWaalsContact CE1-CB 3.44Å; F163-P171 HydrophobicContact CE1-CG 4.1Å; F163-P171 HydrophobicContact CE2-CB 4Å; F163-P171 HydrophobicContact CE2-CG 3.85Å; F163-P171 HydrophobicContact CG-CB 4.02Å; F163-P171 HydrophobicContact CG-CG 3.82Å; F163-P171 HydrophobicContact CZ-CB 3.63Å; F163-P171 HydrophobicContact CZ-CG 4.03Å; F168-P171 VanDerWaalsContact O-CD 3.24Å; F168-P171 WeakPolarHBondContact O-CD 3.48Å; F168-P171 WeakPolarHBondContact O-CG 3.34Å; P171-M174 PolarHBondContact O-N 2.96Å; P171-M175 WeakPolarHBondContact O-CB 3.49Å; P171-M175 PolarHBondContact O-N 3.1Å
172	V	98.4	Very high	97.6	Very high	3 Å²	3	7.3 Å²	7.3	2%	0.018	4%	0.038	C	C	.	.	H	α-helix	trans	-68.2	-44	-173.6	-179.1	0	0	0	0	109.9	I102 F123 F126 N169 D170 M174 M175 L176 V202	I102-V172 HydrophobicContact CD1-CG1 4.1Å; I102-V172 HydrophobicContact CG2-CG1 4.25Å; F123-V172 HydrophobicContact CE1-CG2 4.3Å; F123-V172 HydrophobicContact CZ-CG2 4.39Å; F126-V172 HydrophobicContact CD2-CG2 3.89Å; F126-V172 HydrophobicContact CE2-CG2 3.9Å; N169-V172 PolarHBondContact O-N 2.83Å; D170-V172 VanDerWaalsContact C-N 3.31Å; D170-V172 PolarHBondContact O-N 2.83Å; V172-M174 VanDerWaalsContact C-N 3.34Å; V172-M174 PolarHBondContact O-N 3.37Å; V172-M175 PolarHBondContact O-N 3.24Å; V172-L176 WeakPolarHBondContact O-CG 3.2Å; V172-L176 PolarHBondContact O-N 3.2Å; V172-L176 VanDerWaalsContact O-N 3.11Å; V172-V202 HydrophobicContact CB-CG1 4.29Å; V172-V202 HydrophobicContact CG1-CG1 4.35Å; V172-V202 HydrophobicContact CG1-CG2 4.48Å
173	A	98.4	Very high	97.7	Very high	0 Å²	0	8.7 Å²	8.7	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-60.5	-44.2	175.4	0	0	0	0	0	111.6	N169 D170 L176 L177 V202 K203 V206	N169-A173 PolarHBondContact O-N 3.44Å; D170-A173 PolarHBondContact O-N 2.99Å; A173-L176 PolarHBondContact O-N 3.26Å; A173-L177 WeakPolarHBondContact O-CB 3.46Å; A173-L177 PolarHBondContact O-N 3.31Å; A173-V202 HydrophobicContact CB-CB 4.05Å; A173-V202 HydrophobicContact CB-CG1 3.95Å; A173-K203 HydrophobicContact CB-CB 3.71Å; A173-V206 HydrophobicContact CB-CG2 4.06Å
174	M	98.5	Very high	97.8	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-68.7	-37.1	179.3	-66.2	-54.2	-62.8	0	0	112.8	D170 P171 V172 L177 F178 F209 V360 W361	D170-M174 WeakPolarHBondContact O-CG 3.29Å; D170-M174 PolarHBondContact O-N 3.06Å; P171-M174 PolarHBondContact O-N 2.96Å; V172-M174 VanDerWaalsContact C-N 3.34Å; V172-M174 PolarHBondContact O-N 3.37Å; M174-L177 HydrophobicContact CE-CD2 3.71Å; M174-L177 WeakPolarHBondContact O-CB 3.3Å; M174-L177 PolarHBondContact O-N 2.6Å; M174-L177 HydrophobicContact SD-CD2 4.01Å; M174-F178 HydrophobicContact CB-CE2 4.3Å; M174-F178 HydrophobicContact CE-CE2 4.06Å; M174-F178 HydrophobicContact CE-CZ 4.06Å; M174-F178 WeakPolarHBondContact O-CD2 3.13Å; M174-F178 PolarHBondContact O-N 2.89Å; M174-F209 HydrophobicContact CE-CE2 4.4Å; M174-F209 HydrophobicContact CE-CZ 4.23Å; M174-V360 HydrophobicContact CG-CG1 4.25Å; M174-V360 HydrophobicContact CG-CG2 4.47Å; M174-W361 WeakPolarHBondContact CE-O 3.34Å
175	M	98.7	Very high	97.7	Very high	25 Å²	25	9.3 Å²	9.3	12%	0.123	5%	0.049	C	C	.	.	H	α-helix	trans	-58.3	-49.3	173.6	-175.8	-178.7	62.9	0	0	111.1	F126 V129 T130 L133 P171 V172 L177 F178 A179	F126-M175 HydrophobicContact CB-SD 4.01Å; F126-M175 HydrophobicContact CD1-CE 3.86Å; F126-M175 HydrophobicContact CD1-SD 4.03Å; F126-M175 HydrophobicContact CE1-CE 4.29Å; F126-M175 HydrophobicContact CG-CE 4.24Å; F126-M175 HydrophobicContact CG-SD 4.28Å; V129-M175 HydrophobicContact CB-SD 3.98Å; V129-M175 HydrophobicContact CG1-CG 4.07Å; V129-M175 HydrophobicContact CG1-SD 3.78Å; T130-M175 VanDerWaalsContact OG1-CB 3.32Å; T130-M175 WeakPolarHBondContact OG1-CB 3.4Å; T130-M175 WeakPolarHBondContact OG1-CG 3.32Å; L133-M175 HydrophobicContact CD1-CG 4.16Å; L133-M175 WeakPolarHBondContact CD1-O 3.21Å; P171-M175 WeakPolarHBondContact O-CB 3.49Å; P171-M175 PolarHBondContact O-N 3.1Å; V172-M175 PolarHBondContact O-N 3.24Å; M175-L177 VanDerWaalsContact C-N 3.33Å; M175-L177 PolarHBondContact O-N 3.01Å; M175-F178 PolarHBondContact O-N 3.4Å; M175-A179 PolarHBondContact O-N 3.28Å
176	L	98.8	Very high	97.7	Very high	37 Å²	37	12 Å²	12	19%	0.194	6%	0.063	C	C	.	.	H	α-helix	trans	-62.4	-40.3	177	-68	174.3	0	0	0	111.6	I102 V172 A173 F178 A179 A180 V195 L198 A199 V202	I102-L176 HydrophobicContact CD1-CD1 4.41Å; V172-L176 WeakPolarHBondContact O-CG 3.2Å; V172-L176 PolarHBondContact O-N 3.2Å; V172-L176 VanDerWaalsContact O-N 3.11Å; A173-L176 PolarHBondContact O-N 3.26Å; L176-F178 PolarHBondContact O-N 2.81Å; L176-A179 WeakPolarHBondContact O-CB 3.44Å; L176-A179 PolarHBondContact O-N 3.42Å; L176-A180 PolarHBondContact O-N 3.39Å; L176-V195 HydrophobicContact CB-CG1 4.48Å; L176-V195 VanDerWaalsContact O-CG1 3.32Å; L176-V195 WeakPolarHBondContact O-CG1 3.48Å; L176-L198 HydrophobicContact CD1-CB 4.39Å; L176-A199 HydrophobicContact CB-CB 3.62Å; L176-V202 HydrophobicContact CD1-CG2 3.96Å
177	L	98.7	Very high	97.7	Very high	1 Å²	1	12 Å²	12	1%	0.005	8%	0.077	C	C	.	.	H	α-helix	trans	-61.5	-42.8	175	172.5	65.6	0	0	0	112.7	A173 M174 M175 A179 A180 T181 Y196 A199 V206 F209	A173-L177 WeakPolarHBondContact O-CB 3.46Å; A173-L177 PolarHBondContact O-N 3.31Å; M174-L177 HydrophobicContact CE-CD2 3.71Å; M174-L177 WeakPolarHBondContact O-CB 3.3Å; M174-L177 PolarHBondContact O-N 2.6Å; M174-L177 HydrophobicContact SD-CD2 4.01Å; M175-L177 VanDerWaalsContact C-N 3.33Å; M175-L177 PolarHBondContact O-N 3.01Å; L177-A179 VanDerWaalsContact C-N 3.29Å; L177-A179 PolarHBondContact O-N 2.68Å; L177-A180 WeakPolarHBondContact O-CB 3.31Å; L177-A180 PolarHBondContact O-N 3.49Å; L177-T181 PolarHBondContact O-N 3.07Å; L177-T181 PolarHBondContact O-OG1 2.74Å; L177-Y196 HydrophobicContact CD1-CD2 3.79Å; L177-Y196 HydrophobicContact CD1-CE2 3.95Å; L177-A199 HydrophobicContact CB-CB 4.29Å; L177-V206 HydrophobicContact CB-CG1 4.46Å; L177-V206 HydrophobicContact CD1-CG1 4Å; L177-V206 HydrophobicContact CD2-CG1 4.48Å; L177-F209 HydrophobicContact CD1-CD1 4.38Å; L177-F209 HydrophobicContact CD1-CD2 4.37Å; L177-F209 HydrophobicContact CD1-CG 4.17Å; L177-F209 HydrophobicContact CD2-CD1 4.08Å; L177-F209 HydrophobicContact CD2-CD2 3.53Å; L177-F209 HydrophobicContact CD2-CE1 3.78Å; L177-F209 HydrophobicContact CD2-CE2 3.18Å; L177-F209 HydrophobicContact CD2-CG 3.97Å; L177-F209 HydrophobicContact CD2-CZ 3.32Å
178	F	98.8	Very high	97.7	Very high	1 Å²	1	19 Å²	19	0%	0.004	10%	0.104	C	C	.	.	H	α-helix	trans	-68.8	-30	176.3	-69.6	-58.4	0	0	0	112	T130 L133 V134 I137 M174 M175 L176 T181 N182 F341 H364 T365	T130-F178 HydrophobicContact CG2-CD2 3.91Å; T130-F178 HydrophobicContact CG2-CE2 4.22Å; L133-F178 HydrophobicContact CB-CB 3.82Å; L133-F178 HydrophobicContact CD1-CB 4.28Å; V134-F178 HydrophobicContact CG2-CD1 3.99Å; V134-F178 HydrophobicContact CG2-CD2 3.75Å; V134-F178 HydrophobicContact CG2-CE1 4.05Å; V134-F178 HydrophobicContact CG2-CE2 3.81Å; V134-F178 HydrophobicContact CG2-CG 3.86Å; V134-F178 HydrophobicContact CG2-CZ 3.97Å; I137-F178 HydrophobicContact CD1-CB 4.48Å; I137-F178 HydrophobicContact CD1-CD1 3.82Å; M174-F178 HydrophobicContact CB-CE2 4.3Å; M174-F178 HydrophobicContact CE-CE2 4.06Å; M174-F178 HydrophobicContact CE-CZ 4.06Å; M174-F178 WeakPolarHBondContact O-CD2 3.13Å; M174-F178 PolarHBondContact O-N 2.89Å; M175-F178 PolarHBondContact O-N 3.4Å; L176-F178 PolarHBondContact O-N 2.81Å; F178-T181 PolarHBondContact O-N 3.2Å; F178-N182 WeakPolarHBondContact O-CB 3.12Å; F178-N182 PolarHBondContact O-N 3.49Å; F178-N182 PolarHBondContact O-ND2 2.8Å; F178-F341 HydrophobicContact CE1-CE1 4.1Å; F178-F341 AromaticContact CE1-CZ 3.98Å; F178-F341 HydrophobicContact CE1-CZ 3.98Å; F178-H364 HydrophobicContact CE2-CB 4.15Å; F178-H364 HydrophobicContact CZ-CB 3.76Å; F178-T365 HydrophobicContact CE1-CG2 4.2Å; F178-T365 HydrophobicContact CZ-CG2 4.19Å
179	A	98.8	Very high	97.7	Very high	26 Å²	26	19.4 Å²	19.4	22%	0.215	11%	0.106	C	C	.	.	H	α-helix	trans	-65.1	-47	170	0	0	0	0	0	111.2	L133 M175 L176 L177 T181 N182 L183 V195	L133-A179 HydrophobicContact CD1-CB 3.97Å; L133-A179 HydrophobicContact CD2-CB 4.33Å; M175-A179 PolarHBondContact O-N 3.28Å; L176-A179 WeakPolarHBondContact O-CB 3.44Å; L176-A179 PolarHBondContact O-N 3.42Å; L177-A179 VanDerWaalsContact C-N 3.29Å; L177-A179 PolarHBondContact O-N 2.68Å; A179-T181 VanDerWaalsContact C-N 3.32Å; A179-T181 PolarHBondContact O-N 3.06Å; A179-N182 WeakPolarHBondContact O-CB 3.42Å; A179-N182 PolarHBondContact O-N 2.94Å; A179-L183 WeakPolarHBondContact O-CG 3.38Å; A179-L183 PolarHBondContact O-N 3.47Å; A179-V195 HydrophobicContact CB-CG1 4.08Å
180	A	98.8	Very high	97.7	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-57.8	-43.6	174	0	0	0	0	0	112.2	L176 L177 N182 L183 F184 G192 V195	L176-A180 PolarHBondContact O-N 3.39Å; L177-A180 WeakPolarHBondContact O-CB 3.31Å; L177-A180 PolarHBondContact O-N 3.49Å; A180-N182 VanDerWaalsContact C-N 3.34Å; A180-N182 PolarHBondContact O-N 2.95Å; A180-L183 WeakPolarHBondContact O-CB 3.47Å; A180-L183 PolarHBondContact O-N 3.36Å; A180-F184 HydrophobicContact CB-CE2 4.17Å; A180-F184 HydrophobicContact CB-CZ 4.41Å; A180-F184 WeakPolarHBondContact O-CD2 3.41Å; A180-F184 VanDerWaalsContact O-CG 3.3Å; A180-F184 WeakPolarHBondContact O-CG 3.42Å; A180-F184 PolarHBondContact O-N 3.09Å; A180-G192 WeakPolarHBondContact CB-O 3.43Å; A180-V195 HydrophobicContact CB-CB 4.09Å; A180-V195 HydrophobicContact CB-CG1 4.03Å
181	T	98.6	Very high	97.8	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-60.2	-44.5	176.9	-56	0	0	0	0	111.5	I137 L177 F178 A179 L183 F184 L185 V337 L340	I137-T181 HydrophobicContact CD1-CG2 3.75Å; I137-T181 HydrophobicContact CG1-CG2 4.26Å; L177-T181 PolarHBondContact O-N 3.07Å; L177-T181 PolarHBondContact O-OG1 2.74Å; F178-T181 PolarHBondContact O-N 3.2Å; A179-T181 VanDerWaalsContact C-N 3.32Å; A179-T181 PolarHBondContact O-N 3.06Å; T181-L183 VanDerWaalsContact C-N 3.31Å; T181-L183 PolarHBondContact O-N 2.78Å; T181-F184 PolarHBondContact O-N 3.38Å; T181-L185 HydrophobicContact CG2-CD1 4.44Å; T181-L185 VanDerWaalsContact O-CG 3.31Å; T181-L185 WeakPolarHBondContact O-CG 3.48Å; T181-L185 PolarHBondContact O-N 3.36Å; T181-V337 HydrophobicContact CG2-CG2 4.49Å; T181-L340 HydrophobicContact CG2-CD1 4.14Å
182	N	98.6	Very high	97.9	Very high	5 Å²	5	28.1 Å²	28.1	3%	0.027	16%	0.155	C	C	.	.	H	α-helix	trans	-60.6	-40.2	175.8	-90	-76.5	0	0	0	112.5	L133 R136 R140 F178 A179 A180 L185 D186	L133-N182 PolarHBondContact O-ND2 3.25Å; R136-N182 WeakPolarHBondContact CD-OD1 3.27Å; R136-N182 VanDerWaalsContact CG-OD1 3.24Å; R136-N182 WeakPolarHBondContact CG-OD1 3.29Å; R136-N182 PolarHBondContact NH1-O 3.39Å; R136-N182 PolarHBondContact NH1-OD1 3.07Å; R140-N182 PolarHBondContact NH2-O 3.46Å; F178-N182 WeakPolarHBondContact O-CB 3.12Å; F178-N182 PolarHBondContact O-N 3.49Å; F178-N182 PolarHBondContact O-ND2 2.8Å; A179-N182 WeakPolarHBondContact O-CB 3.42Å; A179-N182 PolarHBondContact O-N 2.94Å; A180-N182 VanDerWaalsContact C-N 3.34Å; A180-N182 PolarHBondContact O-N 2.95Å; N182-L185 PolarHBondContact O-N 3.26Å; N182-D186 VanDerWaalsContact O-CG 3.28Å; N182-D186 PolarHBondContact O-N 2.9Å; N182-D186 VanDerWaalsContact O-OD2 3.05Å
183	L	98.5	Very high	97.9	Very high	30 Å²	30	28 Å²	28	16%	0.157	15%	0.154	C	C	.	.	H	α-helix	trans	-65.7	-38.8	175.9	-70.1	167.2	0	0	0	112.7	A179 A180 T181 L185 D186 G187 Y188 L191 V195	A179-L183 WeakPolarHBondContact O-CG 3.38Å; A179-L183 PolarHBondContact O-N 3.47Å; A180-L183 WeakPolarHBondContact O-CB 3.47Å; A180-L183 PolarHBondContact O-N 3.36Å; T181-L183 VanDerWaalsContact C-N 3.31Å; T181-L183 PolarHBondContact O-N 2.78Å; L183-L185 VanDerWaalsContact C-N 3.34Å; L183-D186 PolarHBondContact O-N 3.32Å; L183-G187 PolarHBondContact O-N 3.06Å; L183-Y188 HydrophobicContact CD2-CD2 4.27Å; L183-Y188 PolarHBondContact O-N 3.14Å; L183-L191 HydrophobicContact CD1-CB 4.45Å; L183-L191 HydrophobicContact CD1-CD2 4.14Å; L183-L191 HydrophobicContact CD1-CG 3.83Å; L183-L191 HydrophobicContact CD2-CD2 3.8Å; L183-L191 HydrophobicContact CD2-CG 4.33Å; L183-V195 HydrophobicContact CD1-CB 4.16Å; L183-V195 HydrophobicContact CD1-CG2 3.69Å
184	F	97.4	Very high	97.9	Very high	3 Å²	3	28.4 Å²	28.4	1%	0.013	16%	0.158	C	C	.	.	H	α-helix	trans	-61.8	-44.2	173.6	-61	-40.8	0	0	0	111.6	A180 T181 D186 G187 W189 G192 L213 I336 L340	A180-F184 HydrophobicContact CB-CE2 4.17Å; A180-F184 HydrophobicContact CB-CZ 4.41Å; A180-F184 WeakPolarHBondContact O-CD2 3.41Å; A180-F184 VanDerWaalsContact O-CG 3.3Å; A180-F184 WeakPolarHBondContact O-CG 3.42Å; A180-F184 PolarHBondContact O-N 3.09Å; T181-F184 PolarHBondContact O-N 3.38Å; F184-D186 PolarHBondContact O-N 3.02Å; F184-G187 PolarHBondContact O-N 3.28Å; F184-W189 HydrophobicContact CB-CE3 4.16Å; F184-W189 HydrophobicContact CB-CH2 4.25Å; F184-W189 HydrophobicContact CB-CZ3 3.97Å; F184-W189 HydrophobicContact CD1-CD2 4.08Å; F184-W189 AromaticContact CD1-CE3 3.37Å; F184-W189 HydrophobicContact CD1-CE3 3.37Å; F184-W189 AromaticContact CD1-CZ3 3.8Å; F184-W189 HydrophobicContact CD1-CZ3 3.8Å; F184-W189 AromaticContact CE1-CE3 4Å; F184-W189 HydrophobicContact CE1-CE3 4Å; F184-W189 AromaticContact CG-CE3 3.98Å; F184-W189 HydrophobicContact CG-CE3 3.98Å; F184-W189 AromaticContact CG-CZ3 3.95Å; F184-W189 HydrophobicContact CG-CZ3 3.95Å; F184-G192 VanDerWaalsContact CE1-CA 3.47Å; F184-G192 VanDerWaalsContact CZ-C 3.41Å; F184-G192 WeakPolarHBondContact CZ-O 3.36Å; F184-L213 HydrophobicContact CD2-CD1 4.24Å; F184-L213 HydrophobicContact CE1-CD1 4.02Å; F184-L213 HydrophobicContact CE2-CD1 3.61Å; F184-L213 HydrophobicContact CE2-CD2 4.43Å; F184-L213 HydrophobicContact CZ-CD1 3.49Å; F184-L213 VanDerWaalsContact CZ-CD1 3.49Å; F184-L213 HydrophobicContact CZ-CD2 4.07Å; F184-L213 HydrophobicContact CZ-CG 4.45Å; F184-I336 HydrophobicContact CB-CG2 4.39Å; F184-L340 HydrophobicContact CD2-CD1 4.11Å
185	L	95.5	Very high	97.9	Very high	10 Å²	10	29.5 Å²	29.5	5%	0.052	17%	0.165	C	C	.	.	H	α-helix	trans	-65.2	-28.3	176.9	-64.1	174.2	0	0	0	111.8	I137 R140 T181 N182 L183 G187 E333 I336 V337	I137-L185 HydrophobicContact CB-CD1 4.49Å; I137-L185 HydrophobicContact CG1-CD1 3.99Å; I137-L185 HydrophobicContact CG2-CD1 4.38Å; R140-L185 VanDerWaalsContact CZ-C 3.48Å; R140-L185 PolarHBondContact NH1-O 3.08Å; R140-L185 PolarHBondContact NH2-O 3.41Å; T181-L185 HydrophobicContact CG2-CD1 4.44Å; T181-L185 VanDerWaalsContact O-CG 3.31Å; T181-L185 WeakPolarHBondContact O-CG 3.48Å; T181-L185 PolarHBondContact O-N 3.36Å; N182-L185 PolarHBondContact O-N 3.26Å; L183-L185 VanDerWaalsContact C-N 3.34Å; L185-G187 VanDerWaalsContact C-N 3.26Å; L185-E333 HydrophobicContact CD2-CB 3.84Å; L185-E333 HydrophobicContact CD2-CG 4.08Å; L185-E333 WeakPolarHBondContact CD2-O 3.39Å; L185-I336 HydrophobicContact CD2-CB 4.13Å; L185-I336 HydrophobicContact CD2-CD1 4.27Å; L185-I336 HydrophobicContact CD2-CG2 4.32Å; L185-V337 HydrophobicContact CD1-CG2 3.81Å; L185-V337 HydrophobicContact CD2-CG2 3.65Å; L185-V337 HydrophobicContact CG-CG2 4.16Å
186	D	95.1	Very high	97.9	Very high	60 Å²	60	28.9 Å²	28.9	32%	0.321	16%	0.162	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.3	-2.7	174.9	-69.7	-34.4	0	0	0	113.5	R136 R140 N182 L183 F184 Y188	R136-D186 IonicContact CZ-OD1 3.84Å; R136-D186 IonicContact CZ-OD2 2.8Å; R136-D186 VanDerWaalsContact CZ-OD2 3.23Å; R136-D186 IonicContact NH1-OD1 2.66Å; R136-D186 IonicContact NH1-OD2 3.61Å; R136-D186 PolarHBondContact NH1-OD2 3.29Å; R136-D186 IonicContact NH2-OD1 2.79Å; R136-D186 PolarHBondContact NH2-OD1 3.4Å; R136-D186 IonicContact NH2-OD2 2.65Å; R136-D186 PolarHBondContact NH2-OD2 3.21Å; R140-D186 IonicContact CZ-OD1 3.95Å; R140-D186 IonicContact NH1-OD1 2.72Å; R140-D186 VanDerWaalsContact NH2-CG 3.28Å; R140-D186 IonicContact NH2-OD1 3.84Å; R140-D186 PolarHBondContact NH2-OD1 2.7Å; R140-D186 IonicContact NH2-OD2 3.83Å; N182-D186 VanDerWaalsContact O-CG 3.28Å; N182-D186 PolarHBondContact O-N 2.9Å; N182-D186 VanDerWaalsContact O-OD2 3.05Å; L183-D186 PolarHBondContact O-N 3.32Å; F184-D186 PolarHBondContact O-N 3.02Å; D186-Y188 VanDerWaalsContact C-N 3.27Å; D186-Y188 HydrophobicContact CB-CD2 3.51Å; D186-Y188 HydrophobicContact CB-CE2 3.9Å; D186-Y188 PolarHBondContact O-N 2.91Å
187	G	94.4	Very high	97.9	Very high	45 Å²	45	27.3 Å²	27.3	46%	0.464	15%	0.153	S	C	.	.	T	Hydrogen-bonded Turn	trans	79	2.5	-175.7	0	0	0	0	0	114.5	L183 F184 L185 W189	L183-G187 PolarHBondContact O-N 3.06Å; F184-G187 PolarHBondContact O-N 3.28Å; L185-G187 VanDerWaalsContact C-N 3.26Å; G187-W189 PolarHBondContact O-N 2.89Å
188	Y	97	Very high	97.9	Very high	147 Å²	147	30.5 Å²	30.5	58%	0.576	17%	0.17	S	C	*	.			trans	-81	57.8	175.5	-63.6	-65.9	0	0	0	111.8	L183 D186 T190 L191 G192	L183-Y188 HydrophobicContact CD2-CD2 4.27Å; L183-Y188 PolarHBondContact O-N 3.14Å; D186-Y188 VanDerWaalsContact C-N 3.27Å; D186-Y188 HydrophobicContact CB-CD2 3.51Å; D186-Y188 HydrophobicContact CB-CE2 3.9Å; D186-Y188 PolarHBondContact O-N 2.91Å; Y188-T190 PolarHBondContact O-N 3.12Å; Y188-L191 PolarHBondContact O-N 3.17Å; Y188-G192 PolarHBondContact O-N 2.66Å
189	W	97.1	Very high	97.9	Very high	14 Å²	14	30.5 Å²	30.5	5%	0.053	17%	0.17	C	C	.	.	H	α-helix	trans	-60.2	-40.5	-170.1	-69.9	94.4	0	0	0	115.2	F184 G187 G192 C193 C216 L217 E220 F221 I336	F184-W189 HydrophobicContact CB-CE3 4.16Å; F184-W189 HydrophobicContact CB-CH2 4.25Å; F184-W189 HydrophobicContact CB-CZ3 3.97Å; F184-W189 HydrophobicContact CD1-CD2 4.08Å; F184-W189 AromaticContact CD1-CE3 3.37Å; F184-W189 HydrophobicContact CD1-CE3 3.37Å; F184-W189 AromaticContact CD1-CZ3 3.8Å; F184-W189 HydrophobicContact CD1-CZ3 3.8Å; F184-W189 AromaticContact CE1-CE3 4Å; F184-W189 HydrophobicContact CE1-CE3 4Å; F184-W189 AromaticContact CG-CE3 3.98Å; F184-W189 HydrophobicContact CG-CE3 3.98Å; F184-W189 AromaticContact CG-CZ3 3.95Å; F184-W189 HydrophobicContact CG-CZ3 3.95Å; G187-W189 PolarHBondContact O-N 2.89Å; W189-G192 PolarHBondContact O-N 3.12Å; W189-C193 WeakPolarHBondContact O-CB 3.31Å; W189-C193 PolarHBondContact O-N 3.1Å; W189-C193 PolarHBondContact O-SG 3.29Å; W189-C216 HydrophobicContact CH2-CB 4.05Å; W189-C216 HydrophobicContact CZ3-CB 4.08Å; W189-L217 HydrophobicContact CE3-CD2 3.84Å; W189-L217 HydrophobicContact CZ3-CD2 4.34Å; W189-E220 HydrophobicContact CZ2-CB 4.22Å; W189-E220 HydrophobicContact CZ2-CG 3.97Å; W189-F221 HydrophobicContact CB-CE2 3.69Å; W189-F221 HydrophobicContact CB-CZ 3.65Å; W189-F221 AromaticContact CD1-CE2 3.87Å; W189-F221 AromaticContact CD1-CZ 3.38Å; W189-F221 AromaticContact CD2-CE2 3.73Å; W189-F221 HydrophobicContact CD2-CE2 3.73Å; W189-F221 HydrophobicContact CD2-CZ 4.08Å; W189-F221 HydrophobicContact CE3-CE2 4.24Å; W189-F221 AromaticContact CG-CE2 3.48Å; W189-F221 HydrophobicContact CG-CE2 3.48Å; W189-F221 VanDerWaalsContact CG-CE2 3.48Å; W189-F221 AromaticContact CG-CZ 3.42Å; W189-F221 HydrophobicContact CG-CZ 3.42Å; W189-F221 VanDerWaalsContact CG-CZ 3.42Å; W189-F221 AromaticContact NE1-CZ 3.93Å; W189-I336 HydrophobicContact CH2-CD1 3.72Å; W189-I336 HydrophobicContact CH2-CG1 4.11Å; W189-I336 HydrophobicContact CH2-CG2 4.42Å; W189-I336 HydrophobicContact CZ2-CD1 3.67Å; W189-I336 HydrophobicContact CZ2-CG1 4.45Å
190	T	97.9	Very high	97.9	Very high	79 Å²	79	29.7 Å²	29.7	49%	0.485	16%	0.163	S	C	.	.	H	α-helix	trans	-65	-46.2	179	-54.9	0	0	0	0	111.1	Y188 C193 G194 L232	Y188-T190 PolarHBondContact O-N 3.12Å; T190-C193 PolarHBondContact O-N 3.17Å; T190-G194 PolarHBondContact O-N 3.11Å; T190-L232 HydrophobicContact CG2-CD2 3.57Å; T190-L232 WeakPolarHBondContact O-CD2 3.37Å
191	L	98.4	Very high	97.8	Very high	104 Å²	104	29.7 Å²	29.7	55%	0.545	16%	0.163	S	C	.	.	H	α-helix	trans	-65.5	-41.2	176	-175.9	61	0	0	0	110.9	L183 Y188 C193 G194 V195	L183-L191 HydrophobicContact CD1-CB 4.45Å; L183-L191 HydrophobicContact CD1-CD2 4.14Å; L183-L191 HydrophobicContact CD1-CG 3.83Å; L183-L191 HydrophobicContact CD2-CD2 3.8Å; L183-L191 HydrophobicContact CD2-CG 4.33Å; Y188-L191 PolarHBondContact O-N 3.17Å; L191-C193 VanDerWaalsContact C-N 3.32Å; L191-C193 PolarHBondContact O-N 3.22Å; L191-G194 WeakPolarHBondContact O-CA 3.33Å; L191-G194 PolarHBondContact O-N 2.93Å; L191-G194 VanDerWaalsContact O-N 3.1Å; L191-V195 WeakPolarHBondContact O-CG2 3.19Å; L191-V195 PolarHBondContact O-N 3.08Å
192	G	98.4	Very high	97.8	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-58.2	-41.2	174	0	0	0	0	0	112.6	A180 F184 Y188 W189 V195 Y196	A180-G192 WeakPolarHBondContact CB-O 3.43Å; F184-G192 VanDerWaalsContact CE1-CA 3.47Å; F184-G192 VanDerWaalsContact CZ-C 3.41Å; F184-G192 WeakPolarHBondContact CZ-O 3.36Å; Y188-G192 PolarHBondContact O-N 2.66Å; W189-G192 PolarHBondContact O-N 3.12Å; G192-V195 PolarHBondContact O-N 3.26Å; G192-Y196 WeakPolarHBondContact O-CB 3.24Å; G192-Y196 PolarHBondContact O-N 3.36Å
193	C	98.7	Very high	97.7	Very high	0 Å²	0	30 Å²	30	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-65.5	-39.5	174.1	-69.2	0	0	0	0	111.6	W189 T190 L191 Y196 S197 K229 C233	W189-C193 WeakPolarHBondContact O-CB 3.31Å; W189-C193 PolarHBondContact O-N 3.1Å; W189-C193 PolarHBondContact O-SG 3.29Å; T190-C193 PolarHBondContact O-N 3.17Å; L191-C193 VanDerWaalsContact C-N 3.32Å; L191-C193 PolarHBondContact O-N 3.22Å; C193-Y196 PolarHBondContact O-N 3.4Å; C193-S197 PolarHBondContact O-N 2.96Å; C193-K229 HydrophobicContact CB-CB 4.33Å; C193-C233 PolarHBondContact O-SG 2.96Å
194	G	98.7	Very high	97.4	Very high	9 Å²	9	30.9 Å²	30.9	9%	0.093	17%	0.168	C	C	.	.	H	α-helix	trans	-58.5	-52.5	173.2	0	0	0	0	0	112.3	T190 L191 Y196 S197 L198	T190-G194 PolarHBondContact O-N 3.11Å; L191-G194 WeakPolarHBondContact O-CA 3.33Å; L191-G194 PolarHBondContact O-N 2.93Å; L191-G194 VanDerWaalsContact O-N 3.1Å; G194-Y196 VanDerWaalsContact C-N 3.34Å; G194-Y196 PolarHBondContact O-N 3.13Å; G194-S197 WeakPolarHBondContact O-CB 3.16Å; G194-S197 PolarHBondContact O-N 3.17Å; G194-L198 WeakPolarHBondContact O-CG 3.45Å; G194-L198 PolarHBondContact O-N 3.33Å
195	V	98.8	Very high	97.3	Very high	23 Å²	23	31 Å²	31	14%	0.139	17%	0.169	C	C	.	.	H	α-helix	trans	-65.7	-36.2	178.3	179.9	0	0	0	0	111.9	L176 A179 A180 L183 L191 G192 S197 L198 A199	L176-V195 HydrophobicContact CB-CG1 4.48Å; L176-V195 VanDerWaalsContact O-CG1 3.32Å; L176-V195 WeakPolarHBondContact O-CG1 3.48Å; A179-V195 HydrophobicContact CB-CG1 4.08Å; A180-V195 HydrophobicContact CB-CB 4.09Å; A180-V195 HydrophobicContact CB-CG1 4.03Å; L183-V195 HydrophobicContact CD1-CB 4.16Å; L183-V195 HydrophobicContact CD1-CG2 3.69Å; L191-V195 WeakPolarHBondContact O-CG2 3.19Å; L191-V195 PolarHBondContact O-N 3.08Å; G192-V195 PolarHBondContact O-N 3.26Å; V195-S197 VanDerWaalsContact C-N 3.34Å; V195-S197 PolarHBondContact O-N 3.11Å; V195-L198 WeakPolarHBondContact O-CB 3.45Å; V195-L198 PolarHBondContact O-N 3.29Å; V195-A199 PolarHBondContact O-N 3.3Å
196	Y	98.8	Very high	97.4	Very high	13 Å²	13	30.6 Å²	30.6	5%	0.051	17%	0.166	C	C	.	.	H	α-helix	trans	-60.8	-43.5	172.7	176.2	-96.2	0	0	0	111.4	L177 G192 C193 G194 L198 A199 V200 V206 F209 A210 L213	L177-Y196 HydrophobicContact CD1-CD2 3.79Å; L177-Y196 HydrophobicContact CD1-CE2 3.95Å; G192-Y196 WeakPolarHBondContact O-CB 3.24Å; G192-Y196 PolarHBondContact O-N 3.36Å; C193-Y196 PolarHBondContact O-N 3.4Å; G194-Y196 VanDerWaalsContact C-N 3.34Å; G194-Y196 PolarHBondContact O-N 3.13Å; Y196-L198 VanDerWaalsContact C-N 3.34Å; Y196-L198 PolarHBondContact O-N 3.32Å; Y196-A199 WeakPolarHBondContact O-CB 3.48Å; Y196-A199 PolarHBondContact O-N 2.82Å; Y196-A199 VanDerWaalsContact O-N 3.15Å; Y196-V200 HydrophobicContact CD1-CG2 4.32Å; Y196-V200 HydrophobicContact CE1-CG2 3.82Å; Y196-V200 WeakPolarHBondContact O-CG2 3.37Å; Y196-V200 PolarHBondContact O-N 3.03Å; Y196-V206 HydrophobicContact CD2-CG1 3.91Å; Y196-V206 HydrophobicContact CE2-CG1 3.38Å; Y196-V206 PolarHBondContact OH-O 3.01Å; Y196-F209 HydrophobicContact CE2-CB 3.99Å; Y196-A210 WeakPolarHBondContact OH-CA 3.24Å; Y196-A210 WeakPolarHBondContact OH-CB 3.43Å; Y196-A210 PolarHBondContact OH-N 3.47Å; Y196-L213 HydrophobicContact CD1-CD2 3.5Å; Y196-L213 VanDerWaalsContact CD1-CD2 3.5Å; Y196-L213 HydrophobicContact CD2-CD2 3.99Å; Y196-L213 HydrophobicContact CE1-CD2 3.7Å; Y196-L213 HydrophobicContact CE2-CD2 4.18Å; Y196-L213 HydrophobicContact CG-CD2 3.66Å
197	S	98.6	Very high	97.5	Very high	3 Å²	3	31.4 Å²	31.4	2%	0.021	17%	0.17	C	C	.	.	H	α-helix	trans	-63.6	-40.3	175.1	-166.2	0	0	0	0	111.6	C193 G194 V195 A199 V200 S201 C233 Q237	C193-S197 PolarHBondContact O-N 2.96Å; G194-S197 WeakPolarHBondContact O-CB 3.16Å; G194-S197 PolarHBondContact O-N 3.17Å; V195-S197 VanDerWaalsContact C-N 3.34Å; V195-S197 PolarHBondContact O-N 3.11Å; S197-A199 VanDerWaalsContact C-N 3.28Å; S197-A199 PolarHBondContact O-N 2.84Å; S197-V200 PolarHBondContact O-N 2.88Å; S197-S201 PolarHBondContact O-N 2.89Å; S197-C233 PolarHBondContact OG-O 3.36Å; S197-Q237 PolarHBondContact O-NE2 2.64Å; S197-Q237 PolarHBondContact OG-NE2 3.12Å
198	L	98.6	Very high	97.6	Very high	69 Å²	69	31 Å²	31	36%	0.361	16%	0.157	S	C	.	.	H	α-helix	trans	-60.4	-36.7	172.3	-65.7	174.1	0	0	0	112.5	L176 G194 V195 Y196 S201 V202 I236 L240	L176-L198 HydrophobicContact CD1-CB 4.39Å; G194-L198 WeakPolarHBondContact O-CG 3.45Å; G194-L198 PolarHBondContact O-N 3.33Å; V195-L198 WeakPolarHBondContact O-CB 3.45Å; V195-L198 PolarHBondContact O-N 3.29Å; Y196-L198 VanDerWaalsContact C-N 3.34Å; Y196-L198 PolarHBondContact O-N 3.32Å; L198-S201 WeakPolarHBondContact CA-OG 3.49Å; L198-S201 PolarHBondContact O-N 3.28Å; L198-S201 PolarHBondContact O-OG 2.76Å; L198-V202 PolarHBondContact O-N 2.87Å; L198-I236 HydrophobicContact CD2-CG2 3.92Å; L198-I236 HydrophobicContact CG-CG2 4.47Å; L198-L240 HydrophobicContact CD2-CD1 3.91Å
199	A	98.6	Very high	97.7	Very high	0 Å²	0	24 Å²	24	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-65.2	-44.2	174.4	0	0	0	0	0	111.8	L176 L177 V195 Y196 S197 S201 V202 K203 V206	L176-A199 HydrophobicContact CB-CB 3.62Å; L177-A199 HydrophobicContact CB-CB 4.29Å; V195-A199 PolarHBondContact O-N 3.3Å; Y196-A199 WeakPolarHBondContact O-CB 3.48Å; Y196-A199 PolarHBondContact O-N 2.82Å; Y196-A199 VanDerWaalsContact O-N 3.15Å; S197-A199 VanDerWaalsContact C-N 3.28Å; S197-A199 PolarHBondContact O-N 2.84Å; A199-S201 VanDerWaalsContact C-N 3.29Å; A199-S201 PolarHBondContact O-N 2.87Å; A199-V202 PolarHBondContact O-N 3.5Å; A199-K203 PolarHBondContact O-N 3.19Å; A199-K203 VanDerWaalsContact O-N 3.16Å; A199-V206 HydrophobicContact CB-CG1 3.98Å; A199-V206 HydrophobicContact CB-CG2 4.08Å
200	V	98.3	Very high	97.7	Very high	9 Å²	9	24.9 Å²	24.9	6%	0.055	14%	0.14	C	C	.	.	H	α-helix	trans	-60.7	-38.3	174.6	173.4	0	0	0	0	111.4	Y196 S197 V202 K203 V206 L207 F257	Y196-V200 HydrophobicContact CD1-CG2 4.32Å; Y196-V200 HydrophobicContact CE1-CG2 3.82Å; Y196-V200 WeakPolarHBondContact O-CG2 3.37Å; Y196-V200 PolarHBondContact O-N 3.03Å; S197-V200 PolarHBondContact O-N 2.88Å; V200-V202 PolarHBondContact O-N 3.48Å; V200-K203 CarbonylContact O-C 3.55Å; V200-K203 PolarHBondContact O-N 2.82Å; V200-V206 HydrophobicContact CG2-CB 3.88Å; V200-V206 HydrophobicContact CG2-CG1 3.74Å; V200-L207 HydrophobicContact CG1-CD2 3.87Å; V200-L207 HydrophobicContact CG1-CG 4.07Å; V200-L207 HydrophobicContact CG2-CD2 4.07Å; V200-L207 HydrophobicContact CG2-CG 4.45Å; V200-F257 HydrophobicContact CG1-CE1 4.13Å
201	S	98	Very high	97.7	Very high	1 Å²	1	23.5 Å²	23.5	1%	0.007	13%	0.133	C	C	.	.	H	α-helix	trans	-71.4	-15	180	68.4	0	0	0	0	113.5	P96 G98 F99 S197 L198 A199 L240	P96-S201 CarbonylContact C-O 3.58Å; P96-S201 VanDerWaalsContact CB-O 3.31Å; P96-S201 WeakPolarHBondContact CB-O 3.48Å; G98-S201 CarbonylContact C-O 3.57Å; G98-S201 WeakPolarHBondContact CA-O 3.35Å; G98-S201 WeakPolarHBondContact CA-OG 3.26Å; G98-S201 PolarHBondContact N-O 3.36Å; F99-S201 PolarHBondContact N-O 3Å; F99-S201 VanDerWaalsContact N-O 3.12Å; S197-S201 PolarHBondContact O-N 2.89Å; L198-S201 WeakPolarHBondContact CA-OG 3.49Å; L198-S201 PolarHBondContact O-N 3.28Å; L198-S201 PolarHBondContact O-OG 2.76Å; A199-S201 VanDerWaalsContact C-N 3.29Å; A199-S201 PolarHBondContact O-N 2.87Å; S201-L240 VanDerWaalsContact OG-CD1 3.29Å; S201-L240 WeakPolarHBondContact OG-CD1 3.43Å
202	V	98.1	Very high	97.7	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-83.8	-47	168.8	178.1	0	0	0	0	110.8	I102 N169 V172 A173 L176 L198 A199 V200	I102-V202 HydrophobicContact CD1-CG2 3.47Å; I102-V202 VanDerWaalsContact CD1-CG2 3.47Å; N169-V202 HydrophobicContact CB-CG1 4.43Å; V172-V202 HydrophobicContact CB-CG1 4.29Å; V172-V202 HydrophobicContact CG1-CG1 4.35Å; V172-V202 HydrophobicContact CG1-CG2 4.48Å; A173-V202 HydrophobicContact CB-CB 4.05Å; A173-V202 HydrophobicContact CB-CG1 3.95Å; L176-V202 HydrophobicContact CD1-CG2 3.96Å; L198-V202 PolarHBondContact O-N 2.87Å; A199-V202 PolarHBondContact O-N 3.5Å; V200-V202 PolarHBondContact O-N 3.48Å
203	K	96.1	Very high	97.7	Very high	12 Å²	12	18.8 Å²	18.8	5%	0.052	11%	0.108	C	C	.	.			trans	-151.8	131.1	-179.6	-160.1	165.6	-163.8	143.2	0	112.2	N169 D170 A173 A199 V200 N205 V206	N169-K203 PolarHBondContact OD1-NZ 2.91Å; D170-K203 HydrophobicContact CB-CD 4.29Å; D170-K203 VanDerWaalsContact OD1-CD 3.24Å; D170-K203 WeakPolarHBondContact OD1-CD 3.09Å; D170-K203 WeakPolarHBondContact OD1-CE 3.48Å; D170-K203 IonicContact OD1-NZ 2.85Å; D170-K203 PolarHBondContact OD1-NZ 3.15Å; D170-K203 IonicContact OD2-NZ 3.44Å; D170-K203 PolarHBondContact OD2-NZ 3.5Å; A173-K203 HydrophobicContact CB-CB 3.71Å; A199-K203 PolarHBondContact O-N 3.19Å; A199-K203 VanDerWaalsContact O-N 3.16Å; V200-K203 CarbonylContact O-C 3.55Å; V200-K203 PolarHBondContact O-N 2.82Å; K203-N205 VanDerWaalsContact CB-OD1 3.25Å; K203-N205 WeakPolarHBondContact CB-OD1 3.46Å; K203-N205 VanDerWaalsContact CG-OD1 3.23Å; K203-N205 WeakPolarHBondContact CG-OD1 3.35Å; K203-N205 PolarHBondContact O-N 3.42Å; K203-N205 VanDerWaalsContact O-N 3.11Å; K203-N205 PolarHBondContact O-OD1 3.34Å; K203-V206 PolarHBondContact O-N 2.66Å
204	M	92.7	Very high	97.6	Very high	47 Å²	47	22.3 Å²	22.3	23%	0.232	13%	0.127	C	C	.	.	G	3₁₀ helix	trans	-64.7	-17.5	-175.5	71.9	174.8	101.1	0	0	114.3	V206 L207 F257	M204-V206 PolarHBondContact O-N 3.26Å; M204-V206 VanDerWaalsContact O-N 3.08Å; M204-L207 HydrophobicContact CB-CD1 4.32Å; M204-L207 WeakPolarHBondContact O-CB 3.46Å; M204-L207 VanDerWaalsContact O-CG 3.3Å; M204-L207 WeakPolarHBondContact O-CG 3.37Å; M204-L207 PolarHBondContact O-N 2.96Å; M204-F257 HydrophobicContact CB-CD1 3.92Å; M204-F257 HydrophobicContact CB-CE1 4.36Å
205	N	94.8	Very high	97.5	Very high	7 Å²	7	22.5 Å²	22.5	4%	0.037	13%	0.125	C	C	.	.	G	3₁₀ helix	trans	-57.9	-26.4	179.5	74.6	-65.6	0	0	0	112.4	K203 L207 L208 W361	K203-N205 VanDerWaalsContact CB-OD1 3.25Å; K203-N205 WeakPolarHBondContact CB-OD1 3.46Å; K203-N205 VanDerWaalsContact CG-OD1 3.23Å; K203-N205 WeakPolarHBondContact CG-OD1 3.35Å; K203-N205 PolarHBondContact O-N 3.42Å; K203-N205 VanDerWaalsContact O-N 3.11Å; K203-N205 PolarHBondContact O-OD1 3.34Å; N205-L207 PolarHBondContact O-N 3.06Å; N205-L207 VanDerWaalsContact O-N 3.13Å; N205-L208 WeakPolarHBondContact O-CB 3.1Å; N205-L208 VanDerWaalsContact O-CG 3.26Å; N205-L208 WeakPolarHBondContact O-CG 3.24Å; N205-L208 PolarHBondContact O-N 2.88Å; N205-W361 HydrophobicContact CB-CD2 3.63Å; N205-W361 VanDerWaalsContact CB-CE2 3.45Å; N205-W361 HydrophobicContact CB-CE3 3.72Å; N205-W361 HydrophobicContact CB-CG 4.39Å; N205-W361 HydrophobicContact CB-CH2 3.55Å; N205-W361 HydrophobicContact CB-CZ2 3.42Å; N205-W361 VanDerWaalsContact CB-CZ2 3.42Å; N205-W361 HydrophobicContact CB-CZ3 3.69Å; N205-W361 VanDerWaalsContact ND2-CD1 3.27Å; N205-W361 VanDerWaalsContact ND2-CG 3.29Å; N205-W361 PolarHBondContact ND2-NE1 3.35Å
206	V	97.9	Very high	97.3	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	12%	0.118	C	C	.	.	G	3₁₀ helix	trans	-61.2	-20.6	176.6	179.8	0	0	0	0	112	A173 L177 Y196 A199 V200 K203 M204 L208 F209	A173-V206 HydrophobicContact CB-CG2 4.06Å; L177-V206 HydrophobicContact CB-CG1 4.46Å; L177-V206 HydrophobicContact CD1-CG1 4Å; L177-V206 HydrophobicContact CD2-CG1 4.48Å; Y196-V206 HydrophobicContact CD2-CG1 3.91Å; Y196-V206 HydrophobicContact CE2-CG1 3.38Å; Y196-V206 PolarHBondContact OH-O 3.01Å; A199-V206 HydrophobicContact CB-CG1 3.98Å; A199-V206 HydrophobicContact CB-CG2 4.08Å; V200-V206 HydrophobicContact CG2-CB 3.88Å; V200-V206 HydrophobicContact CG2-CG1 3.74Å; K203-V206 PolarHBondContact O-N 2.66Å; M204-V206 PolarHBondContact O-N 3.26Å; M204-V206 VanDerWaalsContact O-N 3.08Å; V206-L208 PolarHBondContact O-N 3.15Å; V206-F209 WeakPolarHBondContact O-CB 3.37Å; V206-F209 WeakPolarHBondContact O-CD2 3.47Å; V206-F209 PolarHBondContact O-N 3.23Å
207	L	96.8	Very high	97.2	Very high	77 Å²	77	20.8 Å²	20.8	40%	0.403	12%	0.116	S	C	.	.	G	3₁₀ helix	trans	-61.6	-20.3	172.1	-66.6	173.6	0	0	0	113.4	V200 M204 N205 F209 A210 F257	V200-L207 HydrophobicContact CG1-CD2 3.87Å; V200-L207 HydrophobicContact CG1-CG 4.07Å; V200-L207 HydrophobicContact CG2-CD2 4.07Å; V200-L207 HydrophobicContact CG2-CG 4.45Å; M204-L207 HydrophobicContact CB-CD1 4.32Å; M204-L207 WeakPolarHBondContact O-CB 3.46Å; M204-L207 VanDerWaalsContact O-CG 3.3Å; M204-L207 WeakPolarHBondContact O-CG 3.37Å; M204-L207 PolarHBondContact O-N 2.96Å; N205-L207 PolarHBondContact O-N 3.06Å; N205-L207 VanDerWaalsContact O-N 3.13Å; L207-F209 PolarHBondContact O-N 3.4Å; L207-F209 VanDerWaalsContact O-N 3.15Å; L207-A210 WeakPolarHBondContact O-CB 3.46Å; L207-A210 PolarHBondContact O-N 2.96Å; L207-F257 HydrophobicContact CD1-CD1 4.38Å
208	L	97.2	Very high	96.9	Very high	36 Å²	36	21.9 Å²	21.9	19%	0.188	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	-61.8	-21.2	173.2	-62.5	179.4	0	0	0	112.6	N205 V206 S343 N344 M348 W361	N205-L208 WeakPolarHBondContact O-CB 3.1Å; N205-L208 VanDerWaalsContact O-CG 3.26Å; N205-L208 WeakPolarHBondContact O-CG 3.24Å; N205-L208 PolarHBondContact O-N 2.88Å; V206-L208 PolarHBondContact O-N 3.15Å; L208-S343 CarbonylContact O-C 3.12Å; L208-S343 VanDerWaalsContact O-C 3.25Å; L208-S343 PolarHBondContact O-OG 3.35Å; L208-N344 HydrophobicContact CB-CB 4.41Å; L208-N344 WeakPolarHBondContact CB-OD1 3Å; L208-N344 PolarHBondContact O-N 3.05Å; L208-M348 HydrophobicContact CD1-SD 4.21Å; L208-W361 HydrophobicContact CD1-CE3 4.31Å
209	F	98.4	Very high	96.5	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.106	C	C	.	.	G	3₁₀ helix	trans	-86.4	-13.4	173.3	-63.8	-98.5	0	0	0	113.1	M174 L177 Y196 V206 L207 G212 L213 L340 F341 N344	M174-F209 HydrophobicContact CE-CE2 4.4Å; M174-F209 HydrophobicContact CE-CZ 4.23Å; L177-F209 HydrophobicContact CD1-CD1 4.38Å; L177-F209 HydrophobicContact CD1-CD2 4.37Å; L177-F209 HydrophobicContact CD1-CG 4.17Å; L177-F209 HydrophobicContact CD2-CD1 4.08Å; L177-F209 HydrophobicContact CD2-CD2 3.53Å; L177-F209 HydrophobicContact CD2-CE1 3.78Å; L177-F209 HydrophobicContact CD2-CE2 3.18Å; L177-F209 HydrophobicContact CD2-CG 3.97Å; L177-F209 HydrophobicContact CD2-CZ 3.32Å; Y196-F209 HydrophobicContact CE2-CB 3.99Å; V206-F209 WeakPolarHBondContact O-CB 3.37Å; V206-F209 WeakPolarHBondContact O-CD2 3.47Å; V206-F209 PolarHBondContact O-N 3.23Å; L207-F209 PolarHBondContact O-N 3.4Å; L207-F209 VanDerWaalsContact O-N 3.15Å; F209-G212 PolarHBondContact O-N 3.39Å; F209-L213 PolarHBondContact O-N 3.32Å; F209-L340 HydrophobicContact CD1-CB 4.19Å; F209-L340 WeakPolarHBondContact CD1-O 3.42Å; F209-F341 HydrophobicContact CE1-CD1 4.08Å; F209-N344 HydrophobicContact CD1-CB 3.71Å; F209-N344 HydrophobicContact CD2-CB 3.79Å; F209-N344 HydrophobicContact CE1-CB 3.37Å; F209-N344 HydrophobicContact CE2-CB 3.45Å; F209-N344 VanDerWaalsContact CE2-CB 3.45Å; F209-N344 WeakPolarHBondContact CE2-OD1 3.41Å; F209-N344 HydrophobicContact CG-CB 3.91Å; F209-N344 HydrophobicContact CZ-CB 3.22Å; F209-N344 VanDerWaalsContact CZ-ND2 3.3Å; F209-N344 WeakPolarHBondContact CZ-ND2 3.4Å
210	A	97.9	Very high	96.1	Very high	34 Å²	34	22 Å²	22	28%	0.281	12%	0.12	S	C	.	.	H	α-helix	trans	-61.6	-41.4	-172.8	0	0	0	0	0	113.8	Y196 L207 G212 L213 L214	Y196-A210 WeakPolarHBondContact OH-CA 3.24Å; Y196-A210 WeakPolarHBondContact OH-CB 3.43Å; Y196-A210 PolarHBondContact OH-N 3.47Å; L207-A210 WeakPolarHBondContact O-CB 3.46Å; L207-A210 PolarHBondContact O-N 2.96Å; A210-G212 VanDerWaalsContact C-N 3.34Å; A210-G212 PolarHBondContact O-N 3.04Å; A210-L213 PolarHBondContact O-N 3.1Å; A210-L214 WeakPolarHBondContact O-CB 3.39Å; A210-L214 PolarHBondContact O-N 3.16Å
211	P	98.1	Very high	95.8	Very high	49 Å²	49	23.2 Å²	23.2	32%	0.318	12%	0.124	S	C	.	.	H	α-helix	trans	-60.3	-43	175.3	-23.8	34	0	0	0	112.5	F215 L296 S343	P211-F215 PolarHBondContact O-N 3.38Å; P211-L296 HydrophobicContact CB-CD1 4.02Å; P211-L296 HydrophobicContact CB-CD2 4.2Å; P211-L296 HydrophobicContact CG-CD1 3.74Å; P211-S343 WeakPolarHBondContact CD-OG 3.31Å
212	G	97.7	Very high	95.5	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-64.4	-43.6	174.6	0	0	0	0	0	112.7	F209 A210 F215 C216 I339 S343	F209-G212 PolarHBondContact O-N 3.39Å; A210-G212 VanDerWaalsContact C-N 3.34Å; A210-G212 PolarHBondContact O-N 3.04Å; G212-F215 WeakPolarHBondContact O-CB 3.19Å; G212-F215 PolarHBondContact O-N 3.44Å; G212-C216 PolarHBondContact O-N 3.29Å; G212-C216 PolarHBondContact O-SG 2.75Å; G212-C216 VanDerWaalsContact O-SG 3.36Å; G212-I339 WeakPolarHBondContact O-CG2 3.48Å; G212-S343 PolarHBondContact N-OG 3.43Å; G212-S343 VanDerWaalsContact N-OG 3.08Å
213	L	98.2	Very high	95.3	Very high	6 Å²	6	27.1 Å²	27.1	3%	0.031	15%	0.145	C	C	.	.	H	α-helix	trans	-64.3	-43.8	177.7	178.6	58.6	0	0	0	111.6	F184 Y196 F209 A210 F215 C216 L217 L340	F184-L213 HydrophobicContact CD2-CD1 4.24Å; F184-L213 HydrophobicContact CE1-CD1 4.02Å; F184-L213 HydrophobicContact CE2-CD1 3.61Å; F184-L213 HydrophobicContact CE2-CD2 4.43Å; F184-L213 HydrophobicContact CZ-CD1 3.49Å; F184-L213 VanDerWaalsContact CZ-CD1 3.49Å; F184-L213 HydrophobicContact CZ-CD2 4.07Å; F184-L213 HydrophobicContact CZ-CG 4.45Å; Y196-L213 HydrophobicContact CD1-CD2 3.5Å; Y196-L213 VanDerWaalsContact CD1-CD2 3.5Å; Y196-L213 HydrophobicContact CD2-CD2 3.99Å; Y196-L213 HydrophobicContact CE1-CD2 3.7Å; Y196-L213 HydrophobicContact CE2-CD2 4.18Å; Y196-L213 HydrophobicContact CG-CD2 3.66Å; F209-L213 PolarHBondContact O-N 3.32Å; A210-L213 PolarHBondContact O-N 3.1Å; L213-F215 VanDerWaalsContact C-N 3.29Å; L213-F215 PolarHBondContact O-N 3.4Å; L213-C216 WeakPolarHBondContact O-CB 3.29Å; L213-C216 PolarHBondContact O-N 3.44Å; L213-C216 VanDerWaalsContact O-N 3.17Å; L213-L217 HydrophobicContact CD1-CD1 4.35Å; L213-L217 HydrophobicContact CD1-CG 4.16Å; L213-L217 HydrophobicContact CG-CD1 4.12Å; L213-L217 HydrophobicContact CG-CG 4.39Å; L213-L217 WeakPolarHBondContact O-CG 3.1Å; L213-L217 PolarHBondContact O-N 3.02Å; L213-L340 HydrophobicContact CB-CD2 3.86Å; L213-L340 HydrophobicContact CD1-CD2 4.47Å
214	L	97.7	Very high	95.2	Very high	74 Å²	74	31.3 Å²	31.3	39%	0.387	17%	0.171	S	C	.	.	H	α-helix	trans	-58.2	-44.9	175.1	176.8	61.9	0	0	0	110.8	A210 C216 L217 L218 T226 L230	A210-L214 WeakPolarHBondContact O-CB 3.39Å; A210-L214 PolarHBondContact O-N 3.16Å; L214-C216 PolarHBondContact O-N 2.88Å; L214-L217 PolarHBondContact O-N 3.4Å; L214-L218 HydrophobicContact CD1-CD1 4.11Å; L214-L218 HydrophobicContact CD1-CG 4.16Å; L214-L218 HydrophobicContact CG-CD1 4.09Å; L214-L218 WeakPolarHBondContact O-CB 3.02Å; L214-L218 WeakPolarHBondContact O-CG 3.26Å; L214-L218 PolarHBondContact O-N 3.3Å; L214-T226 HydrophobicContact CD1-CG2 4.3Å; L214-L230 HydrophobicContact CD1-CD1 4.03Å
215	F	95.8	Very high	95.3	Very high	12 Å²	12	35.9 Å²	35.9	5%	0.053	19%	0.186	C	C	.	.	H	α-helix	trans	-59	-47.8	175.1	-173.8	-79.9	0	0	0	111.3	P211 G212 L213 L217 L218 W219 A300 W304 K305 L314 I339	P211-F215 PolarHBondContact O-N 3.38Å; G212-F215 WeakPolarHBondContact O-CB 3.19Å; G212-F215 PolarHBondContact O-N 3.44Å; L213-F215 VanDerWaalsContact C-N 3.29Å; L213-F215 PolarHBondContact O-N 3.4Å; F215-L217 PolarHBondContact O-N 2.94Å; F215-L218 PolarHBondContact O-N 3.34Å; F215-W219 HydrophobicContact CD1-CB 4.41Å; F215-W219 HydrophobicContact CE1-CB 4.24Å; F215-W219 WeakPolarHBondContact O-CB 3.4Å; F215-W219 PolarHBondContact O-N 2.84Å; F215-A300 HydrophobicContact CD2-CB 4.12Å; F215-A300 HydrophobicContact CE2-CB 4.31Å; F215-W304 HydrophobicContact CB-CE3 3.97Å; F215-W304 HydrophobicContact CB-CZ3 4.2Å; F215-W304 HydrophobicContact CD1-CB 4.06Å; F215-W304 HydrophobicContact CD1-CE3 4.32Å; F215-W304 HydrophobicContact CD2-CB 4.34Å; F215-W304 AromaticContact CD2-CE3 3.87Å; F215-W304 HydrophobicContact CD2-CE3 3.87Å; F215-W304 HydrophobicContact CE1-CB 3.61Å; F215-W304 HydrophobicContact CE2-CB 3.9Å; F215-W304 HydrophobicContact CE2-CE3 4.49Å; F215-W304 HydrophobicContact CG-CB 4.41Å; F215-W304 AromaticContact CG-CE3 3.77Å; F215-W304 HydrophobicContact CG-CE3 3.77Å; F215-W304 HydrophobicContact CG-CZ3 4.48Å; F215-W304 VanDerWaalsContact CZ-C 3.47Å; F215-W304 HydrophobicContact CZ-CB 3.52Å; F215-K305 HydrophobicContact CZ-CB 4.42Å; F215-L314 HydrophobicContact CD2-CD1 4.13Å; F215-L314 HydrophobicContact CE2-CD1 3.51Å; F215-L314 HydrophobicContact CZ-CD1 3.8Å; F215-I339 HydrophobicContact CB-CG2 4.37Å; F215-I339 HydrophobicContact CD1-CD1 3.79Å; F215-I339 HydrophobicContact CD1-CG2 4.29Å; F215-I339 HydrophobicContact CE1-CD1 3.88Å
216	C	95.3	Very high	95.4	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-59.9	-42.4	177.3	-71.4	0	0	0	0	112.5	W189 G212 L213 L214 W219 E220	W189-C216 HydrophobicContact CH2-CB 4.05Å; W189-C216 HydrophobicContact CZ3-CB 4.08Å; G212-C216 PolarHBondContact O-N 3.29Å; G212-C216 PolarHBondContact O-SG 2.75Å; G212-C216 VanDerWaalsContact O-SG 3.36Å; L213-C216 WeakPolarHBondContact O-CB 3.29Å; L213-C216 PolarHBondContact O-N 3.44Å; L213-C216 VanDerWaalsContact O-N 3.17Å; L214-C216 PolarHBondContact O-N 2.88Å; C216-W219 PolarHBondContact O-N 3.31Å; C216-E220 VanDerWaalsContact O-CB 3.31Å; C216-E220 WeakPolarHBondContact O-CB 3.45Å; C216-E220 PolarHBondContact O-N 2.92Å
217	L	95.5	Very high	95.3	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-65.9	-45.4	178.7	-70.6	172.4	0	0	0	111.9	W189 L213 L214 F215 W219 E220 F221 T226 K229 L230	W189-L217 HydrophobicContact CE3-CD2 3.84Å; W189-L217 HydrophobicContact CZ3-CD2 4.34Å; L213-L217 HydrophobicContact CD1-CD1 4.35Å; L213-L217 HydrophobicContact CD1-CG 4.16Å; L213-L217 HydrophobicContact CG-CD1 4.12Å; L213-L217 HydrophobicContact CG-CG 4.39Å; L213-L217 WeakPolarHBondContact O-CG 3.1Å; L213-L217 PolarHBondContact O-N 3.02Å; L214-L217 PolarHBondContact O-N 3.4Å; F215-L217 PolarHBondContact O-N 2.94Å; L217-W219 VanDerWaalsContact C-N 3.32Å; L217-W219 PolarHBondContact O-N 2.97Å; L217-E220 PolarHBondContact O-N 3.06Å; L217-F221 HydrophobicContact CD2-CD2 4.04Å; L217-F221 HydrophobicContact CD2-CE2 4.02Å; L217-F221 WeakPolarHBondContact O-CB 3.26Å; L217-F221 PolarHBondContact O-N 3.21Å; L217-T226 VanDerWaalsContact C-OG1 3.3Å; L217-T226 HydrophobicContact CB-CG2 3.73Å; L217-T226 HydrophobicContact CD1-CG2 4.23Å; L217-T226 PolarHBondContact O-OG1 3.25Å; L217-K229 HydrophobicContact CD1-CB 4.41Å; L217-K229 HydrophobicContact CD2-CB 4.45Å; L217-K229 HydrophobicContact CD2-CG 4.32Å; L217-L230 HydrophobicContact CD1-CD2 4Å
218	L	93.9	Very high	95.4	Very high	26 Å²	26	39.7 Å²	39.7	14%	0.136	21%	0.21	C	C	.	.	H	α-helix	trans	-62.9	-42.6	175	-69.1	174.1	0	0	0	110.7	L214 F215 E220 G222 L223 T226 L314 L315 R321	L214-L218 HydrophobicContact CD1-CD1 4.11Å; L214-L218 HydrophobicContact CD1-CG 4.16Å; L214-L218 HydrophobicContact CG-CD1 4.09Å; L214-L218 WeakPolarHBondContact O-CB 3.02Å; L214-L218 WeakPolarHBondContact O-CG 3.26Å; L214-L218 PolarHBondContact O-N 3.3Å; F215-L218 PolarHBondContact O-N 3.34Å; L218-E220 PolarHBondContact O-N 3.34Å; L218-G222 WeakPolarHBondContact O-CA 3.33Å; L218-G222 PolarHBondContact O-N 3.32Å; L218-L223 HydrophobicContact CD2-CB 4.44Å; L218-L223 HydrophobicContact CD2-CD1 4.16Å; L218-T226 HydrophobicContact CD2-CG2 4.28Å; L218-L314 HydrophobicContact CB-CB 4.36Å; L218-L314 VanDerWaalsContact O-O 3.12Å; L218-L315 HydrophobicContact CD1-CD2 4.46Å; L218-L315 HydrophobicContact CD2-CD2 4.24Å; L218-R321 PolarHBondContact O-NH2 2.69Å
219	W	89.9	Confident	95.4	Very high	11 Å²	11	39.3 Å²	39.3	4%	0.042	21%	0.206	C	C	.	.	H	α-helix	trans	-62.3	-42.7	177.1	-178.7	46.1	0	0	0	112.2	F215 C216 L217 L314 R321 H332 Q335 I336	F215-W219 HydrophobicContact CD1-CB 4.41Å; F215-W219 HydrophobicContact CE1-CB 4.24Å; F215-W219 WeakPolarHBondContact O-CB 3.4Å; F215-W219 PolarHBondContact O-N 2.84Å; C216-W219 PolarHBondContact O-N 3.31Å; L217-W219 VanDerWaalsContact C-N 3.32Å; L217-W219 PolarHBondContact O-N 2.97Å; W219-L314 HydrophobicContact CB-CD2 4.27Å; W219-L314 HydrophobicContact CG-CD2 4.48Å; W219-R321 PolarHBondContact O-NH1 2.8Å; W219-R321 PolarHBondContact O-NH2 3.44Å; W219-H332 AromaticContact CH2-CD2 3.77Å; W219-Q335 HydrophobicContact CH2-CB 4.06Å; W219-Q335 HydrophobicContact CH2-CG 3.8Å; W219-Q335 VanDerWaalsContact CZ2-OE1 3.24Å; W219-Q335 HydrophobicContact CZ3-CB 4.2Å; W219-Q335 HydrophobicContact CZ3-CG 3.84Å; W219-I336 HydrophobicContact CZ3-CG1 4.4Å
220	E	89.3	Confident	95.3	Very high	62 Å²	62	43 Å²	43	29%	0.29	23%	0.226	S	C	.	.	H	α-helix	trans	-78.3	-37.4	-178.6	-170.6	66.2	-170.2	0	0	112.9	W189 C216 L217 L218 P318 H332	W189-E220 HydrophobicContact CZ2-CB 4.22Å; W189-E220 HydrophobicContact CZ2-CG 3.97Å; C216-E220 VanDerWaalsContact O-CB 3.31Å; C216-E220 WeakPolarHBondContact O-CB 3.45Å; C216-E220 PolarHBondContact O-N 2.92Å; L217-E220 PolarHBondContact O-N 3.06Å; L218-E220 PolarHBondContact O-N 3.34Å; E220-P318 WeakPolarHBondContact O-CG 3.44Å; E220-H332 IonicContact OE2-CE1 3.2Å; E220-H332 PolarHBondContact OE2-CE1 3.35Å; E220-H332 IonicContact OE2-NE2 3.23Å; E220-H332 PolarHBondContact OE2-NE2 2.79Å
221	F	91.3	Very high	95.3	Very high	33 Å²	33	44.4 Å²	44.4	15%	0.145	23%	0.234	C	C	.	.	H	α-helix	trans	-122.6	-18	-164.5	-62.3	-65.3	0	0	0	115.9	W189 L217 R225	W189-F221 HydrophobicContact CB-CE2 3.69Å; W189-F221 HydrophobicContact CB-CZ 3.65Å; W189-F221 AromaticContact CD1-CE2 3.87Å; W189-F221 AromaticContact CD1-CZ 3.38Å; W189-F221 AromaticContact CD2-CE2 3.73Å; W189-F221 HydrophobicContact CD2-CE2 3.73Å; W189-F221 HydrophobicContact CD2-CZ 4.08Å; W189-F221 HydrophobicContact CE3-CE2 4.24Å; W189-F221 AromaticContact CG-CE2 3.48Å; W189-F221 HydrophobicContact CG-CE2 3.48Å; W189-F221 VanDerWaalsContact CG-CE2 3.48Å; W189-F221 AromaticContact CG-CZ 3.42Å; W189-F221 HydrophobicContact CG-CZ 3.42Å; W189-F221 VanDerWaalsContact CG-CZ 3.42Å; W189-F221 AromaticContact NE1-CZ 3.93Å; L217-F221 HydrophobicContact CD2-CD2 4.04Å; L217-F221 HydrophobicContact CD2-CE2 4.02Å; L217-F221 WeakPolarHBondContact O-CB 3.26Å; L217-F221 PolarHBondContact O-N 3.21Å; F221-R225 HydrophobicContact CB-CB 3.74Å; F221-R225 HydrophobicContact CG-CB 4.47Å
222	G	92.5	Very high	95.3	Very high	1 Å²	1	44.9 Å²	44.9	1%	0.01	23%	0.233	C	C	.	.	H	α-helix	trans	73.8	179.8	-166.2	0	0	0	0	0	113	L218 T226 L314	L218-G222 WeakPolarHBondContact O-CA 3.33Å; L218-G222 PolarHBondContact O-N 3.32Å; G222-T226 VanDerWaalsContact O-CB 3.26Å; G222-T226 WeakPolarHBondContact O-CB 3.31Å; G222-T226 PolarHBondContact O-N 2.84Å; G222-T226 PolarHBondContact O-OG1 2.94Å; G222-L314 WeakPolarHBondContact CA-O 3.32Å
223	L	94.1	Very high	95.4	Very high	82 Å²	82	45.8 Å²	45.8	43%	0.429	24%	0.239	S	C	.	.	H	α-helix	trans	-65.9	-53.1	-171.4	-177.9	62.2	0	0	0	112.8	L218 R225 T226 I227 L315	L218-L223 HydrophobicContact CD2-CB 4.44Å; L218-L223 HydrophobicContact CD2-CD1 4.16Å; L223-R225 VanDerWaalsContact C-N 3.32Å; L223-R225 PolarHBondContact O-N 2.91Å; L223-T226 WeakPolarHBondContact O-CB 3.18Å; L223-T226 PolarHBondContact O-N 3.33Å; L223-I227 PolarHBondContact O-N 2.97Å; L223-L315 HydrophobicContact CB-CB 4.4Å; L223-L315 HydrophobicContact CB-CD2 4.41Å; L223-L315 WeakPolarHBondContact CB-O 3.46Å; L223-L315 HydrophobicContact CD1-CD2 4.49Å; L223-L315 PolarHBondContact N-O 3.15Å
224	V	94.4	Very high	95.3	Very high	101 Å²	101	48 Å²	48	61%	0.612	26%	0.258	S	S	*	.	H	α-helix	trans	-57.8	-44.6	-172.2	178.5	0	0	0	0	111.8	T226 P228	V224-T226 VanDerWaalsContact C-N 3.34Å; V224-P228 WeakPolarHBondContact O-CD 3.48Å
225	R	94.4	Very high	95.4	Very high	143 Å²	143	46.9 Å²	46.9	54%	0.54	26%	0.26	S	S	.	.	H	α-helix	trans	-81.2	-13.7	-179.3	-72.4	-178.6	-177.5	-165.5	-0.2	113.4	F221 L223 P228 K229	F221-R225 HydrophobicContact CB-CB 3.74Å; F221-R225 HydrophobicContact CG-CB 4.47Å; L223-R225 VanDerWaalsContact C-N 3.32Å; L223-R225 PolarHBondContact O-N 2.91Å; R225-P228 WeakPolarHBondContact O-CG 3.32Å; R225-K229 WeakPolarHBondContact O-CD 3.31Å; R225-K229 WeakPolarHBondContact O-CE 3.33Å; R225-K229 PolarHBondContact O-NZ 3.45Å
226	T	96.6	Very high	95.5	Very high	1 Å²	1	47.8 Å²	47.8	1%	0.006	27%	0.265	C	S	.	.	H	α-helix	trans	-77.2	-40	173.5	-67.9	0	0	0	0	111.4	L214 L217 L218 G222 L223 V224 K229 L230	L214-T226 HydrophobicContact CD1-CG2 4.3Å; L217-T226 VanDerWaalsContact C-OG1 3.3Å; L217-T226 HydrophobicContact CB-CG2 3.73Å; L217-T226 HydrophobicContact CD1-CG2 4.23Å; L217-T226 PolarHBondContact O-OG1 3.25Å; L218-T226 HydrophobicContact CD2-CG2 4.28Å; G222-T226 VanDerWaalsContact O-CB 3.26Å; G222-T226 WeakPolarHBondContact O-CB 3.31Å; G222-T226 PolarHBondContact O-N 2.84Å; G222-T226 PolarHBondContact O-OG1 2.94Å; L223-T226 WeakPolarHBondContact O-CB 3.18Å; L223-T226 PolarHBondContact O-N 3.33Å; V224-T226 VanDerWaalsContact C-N 3.34Å; T226-K229 WeakPolarHBondContact O-CB 3.36Å; T226-K229 PolarHBondContact O-N 3.4Å; T226-L230 HydrophobicContact CG2-CD1 3.8Å; T226-L230 HydrophobicContact CG2-CG 3.95Å; T226-L230 PolarHBondContact O-N 2.9Å; T226-L230 VanDerWaalsContact O-N 3.14Å
227	I	97.1	Very high	95.6	Very high	90 Å²	90	49.2 Å²	49.2	46%	0.462	27%	0.272	S	S	.	.	H	α-helix	trans	-45.8	-54.9	179.5	-66.8	166.5	0	0	0	112.7	L223 K229 L230 S231	L223-I227 PolarHBondContact O-N 2.97Å; I227-K229 VanDerWaalsContact C-N 3.27Å; I227-K229 PolarHBondContact O-N 3.41Å; I227-L230 PolarHBondContact O-N 3.09Å; I227-L230 VanDerWaalsContact O-N 3.08Å; I227-S231 PolarHBondContact O-N 3Å; I227-S231 PolarHBondContact O-OG 3.29Å; I227-S231 VanDerWaalsContact O-OG 3.06Å
228	P	97.4	Very high	95.7	Very high	73 Å²	73	54.4 Å²	54.4	47%	0.474	30%	0.299	S	S	.	.	H	α-helix	trans	-62.9	-28.2	-178.1	22.9	-34.1	0	0	0	114.1	V224 R225 L232	V224-P228 WeakPolarHBondContact O-CD 3.48Å; R225-P228 WeakPolarHBondContact O-CG 3.32Å; P228-L232 WeakPolarHBondContact O-CB 3.47Å; P228-L232 PolarHBondContact O-N 3.22Å
229	K	97.5	Very high	95.9	Very high	27 Å²	27	59 Å²	59	12%	0.117	32%	0.323	C	S	.	.	H	α-helix	trans	-70.5	-41.5	174.2	-72.7	88.4	172.2	145.4	0	111.2	C193 L217 R225 T226 I227 L232 C233	C193-K229 HydrophobicContact CB-CB 4.33Å; L217-K229 HydrophobicContact CD1-CB 4.41Å; L217-K229 HydrophobicContact CD2-CB 4.45Å; L217-K229 HydrophobicContact CD2-CG 4.32Å; R225-K229 WeakPolarHBondContact O-CD 3.31Å; R225-K229 WeakPolarHBondContact O-CE 3.33Å; R225-K229 PolarHBondContact O-NZ 3.45Å; T226-K229 WeakPolarHBondContact O-CB 3.36Å; T226-K229 PolarHBondContact O-N 3.4Å; I227-K229 VanDerWaalsContact C-N 3.27Å; I227-K229 PolarHBondContact O-N 3.41Å; K229-L232 WeakPolarHBondContact O-CB 3.5Å; K229-L232 PolarHBondContact O-N 2.83Å; K229-C233 PolarHBondContact O-N 3.28Å; K229-C233 VanDerWaalsContact O-N 3.1Å; K229-C233 PolarHBondContact O-SG 2.55Å
230	L	97.4	Very high	96.3	Very high	77 Å²	77	60.1 Å²	60.1	40%	0.403	33%	0.33	S	S	.	.	H	α-helix	trans	-67.5	-40.4	176	-62.4	-179.9	0	0	0	111.3	L214 L217 T226 I227 L232 C233 A234	L214-L230 HydrophobicContact CD1-CD1 4.03Å; L217-L230 HydrophobicContact CD1-CD2 4Å; T226-L230 HydrophobicContact CG2-CD1 3.8Å; T226-L230 HydrophobicContact CG2-CG 3.95Å; T226-L230 PolarHBondContact O-N 2.9Å; T226-L230 VanDerWaalsContact O-N 3.14Å; I227-L230 PolarHBondContact O-N 3.09Å; I227-L230 VanDerWaalsContact O-N 3.08Å; L230-L232 VanDerWaalsContact C-N 3.29Å; L230-L232 PolarHBondContact O-N 2.78Å; L230-C233 WeakPolarHBondContact O-CB 3.5Å; L230-C233 PolarHBondContact O-N 3Å; L230-C233 VanDerWaalsContact O-N 3.15Å; L230-A234 PolarHBondContact O-N 3.06Å
231	S	97.8	Very high	96.7	Very high	65 Å²	65	57.2 Å²	57.2	46%	0.455	32%	0.316	S	S	.	.	H	α-helix	trans	-60.2	-39.4	173.6	-58.1	0	0	0	0	111.6	I227 A234 A235	I227-S231 PolarHBondContact O-N 3Å; I227-S231 PolarHBondContact O-OG 3.29Å; I227-S231 VanDerWaalsContact O-OG 3.06Å; S231-A234 PolarHBondContact O-N 3.12Å; S231-A235 VanDerWaalsContact O-CB 3.29Å; S231-A235 WeakPolarHBondContact O-CB 3.38Å; S231-A235 PolarHBondContact O-N 3.12Å
232	L	98.3	Very high	97	Very high	58 Å²	58	59.6 Å²	59.6	30%	0.304	33%	0.33	S	S	.	.	H	α-helix	trans	-61.1	-46	172.8	175.7	64.6	0	0	0	111.7	T190 P228 K229 L230 A234 A235 I236	T190-L232 HydrophobicContact CG2-CD2 3.57Å; T190-L232 WeakPolarHBondContact O-CD2 3.37Å; P228-L232 WeakPolarHBondContact O-CB 3.47Å; P228-L232 PolarHBondContact O-N 3.22Å; K229-L232 WeakPolarHBondContact O-CB 3.5Å; K229-L232 PolarHBondContact O-N 2.83Å; L230-L232 VanDerWaalsContact C-N 3.29Å; L230-L232 PolarHBondContact O-N 2.78Å; L232-A234 VanDerWaalsContact C-N 3.32Å; L232-A234 PolarHBondContact O-N 2.82Å; L232-A235 PolarHBondContact O-N 3.1Å; L232-I236 HydrophobicContact CD1-CD1 4.07Å; L232-I236 HydrophobicContact CD1-CG1 4.35Å; L232-I236 HydrophobicContact CG-CD1 4.13Å; L232-I236 WeakPolarHBondContact O-CG1 3.31Å; L232-I236 PolarHBondContact O-N 2.72Å
233	C	98.1	Very high	97.2	Very high	19 Å²	19	61.9 Å²	61.9	13%	0.128	35%	0.345	C	S	.	.	H	α-helix	trans	-56.9	-48.2	176.2	-66.9	0	0	0	0	111.2	C193 S197 K229 L230 I236 Q237	C193-C233 PolarHBondContact O-SG 2.96Å; S197-C233 PolarHBondContact OG-O 3.36Å; K229-C233 PolarHBondContact O-N 3.28Å; K229-C233 VanDerWaalsContact O-N 3.1Å; K229-C233 PolarHBondContact O-SG 2.55Å; L230-C233 WeakPolarHBondContact O-CB 3.5Å; L230-C233 PolarHBondContact O-N 3Å; L230-C233 VanDerWaalsContact O-N 3.15Å; C233-I236 PolarHBondContact O-N 2.8Å; C233-Q237 PolarHBondContact O-N 2.7Å
234	A	97.6	Very high	97.3	Very high	52 Å²	52	58 Å²	58	43%	0.43	33%	0.325	S	S	.	.	H	α-helix	trans	-63.2	-43.4	178.7	0	0	0	0	0	112.3	L230 S231 L232 I236 Q237 L238	L230-A234 PolarHBondContact O-N 3.06Å; S231-A234 PolarHBondContact O-N 3.12Å; L232-A234 VanDerWaalsContact C-N 3.32Å; L232-A234 PolarHBondContact O-N 2.82Å; A234-I236 VanDerWaalsContact C-N 3.31Å; A234-I236 PolarHBondContact O-N 2.8Å; A234-Q237 PolarHBondContact O-N 3.43Å; A234-Q237 VanDerWaalsContact O-N 3.15Å; A234-L238 WeakPolarHBondContact O-CG 3.45Å; A234-L238 PolarHBondContact O-N 3.09Å
235	A	98.4	Very high	97.5	Very high	52 Å²	52	54.9 Å²	54.9	43%	0.43	30%	0.304	S	S	.	.	H	α-helix	trans	-60.4	-39.9	178.2	0	0	0	0	0	112.1	S231 L232 L238 L239	S231-A235 VanDerWaalsContact O-CB 3.29Å; S231-A235 WeakPolarHBondContact O-CB 3.38Å; S231-A235 PolarHBondContact O-N 3.12Å; L232-A235 PolarHBondContact O-N 3.1Å; A235-L238 PolarHBondContact O-N 2.83Å; A235-L239 VanDerWaalsContact O-CB 3.27Å; A235-L239 WeakPolarHBondContact O-CB 3.48Å; A235-L239 PolarHBondContact O-N 3.22Å
236	I	98.4	Very high	97.6	Very high	30 Å²	30	54.6 Å²	54.6	15%	0.154	31%	0.313	C	S	.	.	H	α-helix	trans	-63.6	-43.1	174.9	-70.1	166.5	0	0	0	111.2	L198 L232 C233 A234 L239 L240	L198-I236 HydrophobicContact CD2-CG2 3.92Å; L198-I236 HydrophobicContact CG-CG2 4.47Å; L232-I236 HydrophobicContact CD1-CD1 4.07Å; L232-I236 HydrophobicContact CD1-CG1 4.35Å; L232-I236 HydrophobicContact CG-CD1 4.13Å; L232-I236 WeakPolarHBondContact O-CG1 3.31Å; L232-I236 PolarHBondContact O-N 2.72Å; C233-I236 PolarHBondContact O-N 2.8Å; A234-I236 VanDerWaalsContact C-N 3.31Å; A234-I236 PolarHBondContact O-N 2.8Å; I236-L239 PolarHBondContact O-N 3.49Å; I236-L240 HydrophobicContact CG2-CD1 3.89Å; I236-L240 HydrophobicContact CG2-CG 4.33Å; I236-L240 WeakPolarHBondContact O-CB 3.34Å; I236-L240 VanDerWaalsContact O-CG 3.29Å; I236-L240 WeakPolarHBondContact O-CG 3.22Å; I236-L240 PolarHBondContact O-N 2.9Å
237	Q	97.9	Very high	97.6	Very high	31 Å²	31	59 Å²	59	15%	0.145	34%	0.336	C	S	.	.	H	α-helix	trans	-62.1	-44.9	176.7	-64.7	-56.5	-53.7	0	0	111.5	S197 C233 A234 G241	S197-Q237 PolarHBondContact O-NE2 2.64Å; S197-Q237 PolarHBondContact OG-NE2 3.12Å; C233-Q237 PolarHBondContact O-N 2.7Å; A234-Q237 PolarHBondContact O-N 3.43Å; A234-Q237 VanDerWaalsContact O-N 3.15Å; Q237-G241 PolarHBondContact O-N 3.43Å
238	L	97.6	Very high	97.6	Very high	108 Å²	108	56.5 Å²	56.5	57%	0.565	32%	0.324	S	S	*	.	H	α-helix	trans	-63.7	-43.5	177.9	-68.7	175.7	0	0	0	111.8	A234 A235 G241 L242 L245	A234-L238 WeakPolarHBondContact O-CG 3.45Å; A234-L238 PolarHBondContact O-N 3.09Å; A235-L238 PolarHBondContact O-N 2.83Å; L238-G241 PolarHBondContact O-N 3.46Å; L238-L242 WeakPolarHBondContact O-CA 3.48Å; L238-L242 WeakPolarHBondContact O-CB 3.18Å; L238-L242 PolarHBondContact O-N 3.34Å; L238-L245 HydrophobicContact CD2-CD1 4.01Å
239	L	98.1	Very high	97.5	Very high	122 Å²	122	56.1 Å²	56.1	64%	0.639	32%	0.321	S	S	*	.	H	α-helix	trans	-63.6	-48.1	179.8	-179.4	64.2	0	0	0	111.5	A235 I236 L242	A235-L239 VanDerWaalsContact O-CB 3.27Å; A235-L239 WeakPolarHBondContact O-CB 3.48Å; A235-L239 PolarHBondContact O-N 3.22Å; I236-L239 PolarHBondContact O-N 3.49Å; L239-L242 WeakPolarHBondContact O-CB 3.42Å; L239-L242 PolarHBondContact O-N 3.28Å
240	L	97.9	Very high	97.4	Very high	36 Å²	36	60.1 Å²	60.1	19%	0.188	35%	0.348	C	S	.	.	H	α-helix	trans	-66.6	-39.5	178.3	-67.4	179.1	0	0	0	111.6	A97 Y101 L198 S201 I236 L242	A97-L240 HydrophobicContact CB-CB 4.14Å; A97-L240 WeakPolarHBondContact CB-O 3.26Å; Y101-L240 HydrophobicContact CD2-CD2 3.87Å; Y101-L240 HydrophobicContact CE2-CB 3.97Å; Y101-L240 HydrophobicContact CE2-CD2 3.79Å; Y101-L240 HydrophobicContact CE2-CG 4.45Å; Y101-L240 VanDerWaalsContact CE2-O 3.27Å; Y101-L240 WeakPolarHBondContact CE2-O 3.45Å; Y101-L240 PolarHBondContact OH-O 3.01Å; L198-L240 HydrophobicContact CD2-CD1 3.91Å; S201-L240 VanDerWaalsContact OG-CD1 3.29Å; S201-L240 WeakPolarHBondContact OG-CD1 3.43Å; I236-L240 HydrophobicContact CG2-CD1 3.89Å; I236-L240 HydrophobicContact CG2-CG 4.33Å; I236-L240 WeakPolarHBondContact O-CB 3.34Å; I236-L240 VanDerWaalsContact O-CG 3.29Å; I236-L240 WeakPolarHBondContact O-CG 3.22Å; I236-L240 PolarHBondContact O-N 2.9Å; L240-L242 VanDerWaalsContact C-N 3.28Å; L240-L242 PolarHBondContact O-N 3.29Å
241	G	97.3	Very high	97.2	Very high	0 Å²	0	56.6 Å²	56.6	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-75.6	-11	178.4	0	0	0	0	0	114.7	Q237 L238 F244 L245 Y252	Q237-G241 PolarHBondContact O-N 3.43Å; L238-G241 PolarHBondContact O-N 3.46Å; G241-F244 PolarHBondContact O-N 3.41Å; G241-L245 WeakPolarHBondContact O-CG 3.47Å; G241-L245 PolarHBondContact O-N 2.82Å; G241-Y252 WeakPolarHBondContact CA-OH 3.17Å
242	L	97.8	Very high	97.1	Very high	83 Å²	83	53.8 Å²	53.8	44%	0.435	31%	0.309	S	S	.	.	H	α-helix	trans	-53.3	-48.7	-165.1	-176.6	65.4	0	0	0	114.2	L238 L239 L240 F244 L245 L246	L238-L242 WeakPolarHBondContact O-CA 3.48Å; L238-L242 WeakPolarHBondContact O-CB 3.18Å; L238-L242 PolarHBondContact O-N 3.34Å; L239-L242 WeakPolarHBondContact O-CB 3.42Å; L239-L242 PolarHBondContact O-N 3.28Å; L240-L242 VanDerWaalsContact C-N 3.28Å; L240-L242 PolarHBondContact O-N 3.29Å; L242-F244 VanDerWaalsContact C-N 3.26Å; L242-F244 PolarHBondContact O-N 3.17Å; L242-L245 PolarHBondContact O-N 3.39Å; L242-L246 HydrophobicContact CD1-CD1 4.06Å; L242-L246 HydrophobicContact CD1-CD2 4.36Å; L242-L246 HydrophobicContact CD1-CG 3.97Å; L242-L246 HydrophobicContact CG-CD1 4.01Å; L242-L246 HydrophobicContact CG-CG 4.33Å; L242-L246 VanDerWaalsContact O-CG 3.31Å; L242-L246 WeakPolarHBondContact O-CG 3.29Å; L242-L246 PolarHBondContact O-N 3.45Å
243	P	97	Very high	96.9	Very high	50 Å²	50	55.9 Å²	55.9	33%	0.325	32%	0.32	S	S	.	.	H	α-helix	trans	-57.3	-39.9	178.7	-25.6	35.7	0	0	0	113.2	Y81 N247	Y81-P243 HydrophobicContact CD1-CB 3.78Å; Y81-P243 HydrophobicContact CE1-CB 3.98Å; P243-N247 PolarHBondContact O-N 3.26Å
244	F	97.1	Very high	96.5	Very high	1 Å²	1	57.8 Å²	57.8	0%	0.004	33%	0.334	C	S	.	.	H	α-helix	trans	-77.9	-36.6	-178.2	-47.2	-68.8	0	0	0	111.8	V76 Y81 Y83 A97 V100 G241 L242 L246 N247 N248 Y252	V76-F244 HydrophobicContact CG1-CE1 3.96Å; V76-F244 HydrophobicContact CG1-CZ 4.07Å; V76-F244 HydrophobicContact CG2-CE1 4.05Å; V76-F244 HydrophobicContact CG2-CZ 4.44Å; Y81-F244 AromaticContact CD1-CD1 3.9Å; Y81-F244 HydrophobicContact CD1-CD1 3.9Å; Y81-F244 AromaticContact CD1-CE1 3.66Å; Y81-F244 HydrophobicContact CD1-CE1 3.66Å; Y81-F244 HydrophobicContact CD1-CZ 4.44Å; Y81-F244 HydrophobicContact CE1-CE1 4.42Å; Y81-F244 WeakPolarHBondContact O-CD1 3.33Å; Y83-F244 HydrophobicContact CD2-CB 3.95Å; Y83-F244 AromaticContact CD2-CD1 3.63Å; Y83-F244 HydrophobicContact CD2-CD1 3.63Å; Y83-F244 HydrophobicContact CD2-CE1 4.26Å; Y83-F244 AromaticContact CD2-CG 3.81Å; Y83-F244 HydrophobicContact CD2-CG 3.81Å; Y83-F244 HydrophobicContact CE2-CB 3.87Å; Y83-F244 AromaticContact CE2-CD1 3.26Å; Y83-F244 HydrophobicContact CE2-CD1 3.26Å; Y83-F244 AromaticContact CE2-CD2 3.72Å; Y83-F244 HydrophobicContact CE2-CD2 3.72Å; Y83-F244 AromaticContact CE2-CE1 3.58Å; Y83-F244 HydrophobicContact CE2-CE1 3.58Å; Y83-F244 HydrophobicContact CE2-CE2 4.03Å; Y83-F244 AromaticContact CE2-CG 3.31Å; Y83-F244 HydrophobicContact CE2-CG 3.31Å; Y83-F244 AromaticContact CE2-CZ 3.96Å; Y83-F244 HydrophobicContact CE2-CZ 3.96Å; A97-F244 HydrophobicContact CB-CD2 3.87Å; A97-F244 HydrophobicContact CB-CE2 3.62Å; V100-F244 HydrophobicContact CB-CZ 4.46Å; V100-F244 HydrophobicContact CG1-CZ 4.15Å; V100-F244 HydrophobicContact CG2-CZ 4.43Å; G241-F244 PolarHBondContact O-N 3.41Å; L242-F244 VanDerWaalsContact C-N 3.26Å; L242-F244 PolarHBondContact O-N 3.17Å; F244-L246 VanDerWaalsContact C-N 3.34Å; F244-N247 PolarHBondContact O-N 3.04Å; F244-N248 CarbonylContact O-C 3.52Å; F244-N248 PolarHBondContact O-N 3.22Å; F244-Y252 HydrophobicContact CB-CD2 3.38Å; F244-Y252 HydrophobicContact CB-CE2 3.94Å; F244-Y252 HydrophobicContact CB-CG 3.93Å; F244-Y252 HydrophobicContact CD2-CD2 4.17Å; F244-Y252 AromaticContact CD2-CE2 3.86Å; F244-Y252 HydrophobicContact CD2-CE2 3.86Å; F244-Y252 AromaticContact CG-CD2 3.99Å; F244-Y252 HydrophobicContact CG-CD2 3.99Å; F244-Y252 HydrophobicContact CG-CE2 4.17Å
245	L	97.1	Very high	96.2	Very high	34 Å²	34	59 Å²	59	18%	0.178	33%	0.327	C	S	.	.	H	α-helix	trans	-65.9	-35.5	175.1	-72.9	169.6	0	0	0	112.2	L238 G241 L242 P249 Y252 L253	L238-L245 HydrophobicContact CD2-CD1 4.01Å; G241-L245 WeakPolarHBondContact O-CG 3.47Å; G241-L245 PolarHBondContact O-N 2.82Å; L242-L245 PolarHBondContact O-N 3.39Å; L245-P249 HydrophobicContact CD2-CB 4.19Å; L245-P249 WeakPolarHBondContact O-CB 3.41Å; L245-P249 WeakPolarHBondContact O-CD 3.43Å; L245-P249 WeakPolarHBondContact O-CG 3.4Å; L245-Y252 HydrophobicContact CD2-CD1 3.53Å; L245-Y252 HydrophobicContact CD2-CE1 4.19Å; L245-Y252 HydrophobicContact CD2-CG 4.28Å; L245-Y252 HydrophobicContact CG-CD1 3.85Å; L245-Y252 HydrophobicContact CG-CE1 4.21Å; L245-Y252 HydrophobicContact CG-CG 4.46Å; L245-L253 HydrophobicContact CD2-CD2 4.49Å; L245-L253 HydrophobicContact CD2-CG 4.34Å
246	L	97.5	Very high	95.7	Very high	138 Å²	138	56.5 Å²	56.5	72%	0.723	31%	0.307	S	S	*	.	H	α-helix	trans	-71.1	-33.1	175.8	-70.7	174.8	0	0	0	112.2	L242 F244	L242-L246 HydrophobicContact CD1-CD1 4.06Å; L242-L246 HydrophobicContact CD1-CD2 4.36Å; L242-L246 HydrophobicContact CD1-CG 3.97Å; L242-L246 HydrophobicContact CG-CD1 4.01Å; L242-L246 HydrophobicContact CG-CG 4.33Å; L242-L246 VanDerWaalsContact O-CG 3.31Å; L242-L246 WeakPolarHBondContact O-CG 3.29Å; L242-L246 PolarHBondContact O-N 3.45Å; F244-L246 VanDerWaalsContact C-N 3.34Å
247	N	96.8	Very high	95	Very high	93 Å²	93	57.3 Å²	57.3	50%	0.497	31%	0.309	S	S	.	.	H	α-helix	trans	-81.3	-53.9	-179.3	-169.8	82.7	0	0	0	112.7	D82 P243 F244	D82-N247 WeakPolarHBondContact CB-ND2 3.45Å; D82-N247 PolarHBondContact N-ND2 2.68Å; P243-N247 PolarHBondContact O-N 3.26Å; F244-N247 PolarHBondContact O-N 3.04Å
248	N	96.8	Very high	94.3	Very high	38 Å²	38	57.7 Å²	57.7	20%	0.203	31%	0.312	C	S	.	.			trans	-149.6	87.9	178.5	-174.5	-6	0	0	0	110.8	D82 F244 V250 G251 Y252	D82-N248 VanDerWaalsContact CG-ND2 3.32Å; D82-N248 PolarHBondContact OD1-ND2 3.28Å; D82-N248 VanDerWaalsContact OD1-ND2 3.09Å; D82-N248 WeakPolarHBondContact OD2-CB 3.32Å; D82-N248 PolarHBondContact OD2-ND2 3.38Å; F244-N248 CarbonylContact O-C 3.52Å; F244-N248 PolarHBondContact O-N 3.22Å; N248-V250 VanDerWaalsContact C-N 3.34Å; N248-V250 PolarHBondContact O-N 2.82Å; N248-V250 PolarHBondContact OD1-N 3.01Å; N248-G251 PolarHBondContact O-N 3.37Å; N248-G251 PolarHBondContact OD1-N 2.66Å; N248-Y252 PolarHBondContact O-N 3Å
249	P	95.6	Very high	93.3	Very high	65 Å²	65	59.4 Å²	59.4	42%	0.422	32%	0.321	S	S	.	.	H	α-helix	trans	-63.6	-37	-175.8	4.6	-5.6	0	0	0	113.3	L245 L253	L245-P249 HydrophobicContact CD2-CB 4.19Å; L245-P249 WeakPolarHBondContact O-CB 3.41Å; L245-P249 WeakPolarHBondContact O-CD 3.43Å; L245-P249 WeakPolarHBondContact O-CG 3.4Å; P249-L253 WeakPolarHBondContact O-CB 3.31Å; P249-L253 VanDerWaalsContact O-CG 3.32Å; P249-L253 WeakPolarHBondContact O-CG 3.39Å; P249-L253 PolarHBondContact O-N 3.09Å
250	V	95.1	Very high	91.9	Very high	111 Å²	111	56.5 Å²	56.5	67%	0.673	32%	0.32	S	S	*	.	H	α-helix	trans	-69.2	-43.6	177.9	-179.7	0	0	0	0	110.3	N248 S254	N248-V250 VanDerWaalsContact C-N 3.34Å; N248-V250 PolarHBondContact O-N 2.82Å; N248-V250 PolarHBondContact OD1-N 3.01Å; V250-S254 VanDerWaalsContact O-CB 3.25Å; V250-S254 WeakPolarHBondContact O-CB 3.27Å; V250-S254 PolarHBondContact O-N 3.09Å; V250-S254 PolarHBondContact O-OG 3.48Å
251	G	94.2	Very high	90.9	Very high	3 Å²	3	58.9 Å²	58.9	3%	0.031	33%	0.327	C	S	.	.	H	α-helix	trans	-58.8	-48	175	0	0	0	0	0	112.1	N248 S254 R255	N248-G251 PolarHBondContact O-N 3.37Å; N248-G251 PolarHBondContact OD1-N 2.66Å; G251-S254 PolarHBondContact O-OG 3.33Å; G251-R255 VanDerWaalsContact O-CB 3.29Å; G251-R255 WeakPolarHBondContact O-CB 3.42Å; G251-R255 VanDerWaalsContact O-CG 3.26Å; G251-R255 WeakPolarHBondContact O-CG 3.38Å; G251-R255 PolarHBondContact O-N 3.41Å; G251-R255 VanDerWaalsContact O-N 3.11Å
252	Y	95.5	Very high	89.9	Confident	6 Å²	6	63.8 Å²	63.8	2%	0.024	35%	0.35	C	S	.	.	H	α-helix	trans	-59.9	-54.9	176.7	-179.8	-103.1	0	0	0	112	Y83 A97 G241 F244 L245 N248 S254 R255 A256	Y83-Y252 AromaticContact CD1-CD2 3.81Å; Y83-Y252 HydrophobicContact CD1-CD2 3.81Å; Y83-Y252 HydrophobicContact CD1-CE2 4.34Å; Y83-Y252 AromaticContact CD2-CD2 3.77Å; Y83-Y252 HydrophobicContact CD2-CD2 3.77Å; Y83-Y252 HydrophobicContact CD2-CE2 4.46Å; Y83-Y252 AromaticContact CE1-CD2 3.62Å; Y83-Y252 HydrophobicContact CE1-CD2 3.62Å; Y83-Y252 AromaticContact CE1-CE2 3.68Å; Y83-Y252 HydrophobicContact CE1-CE2 3.68Å; Y83-Y252 AromaticContact CE2-CD2 3.64Å; Y83-Y252 HydrophobicContact CE2-CD2 3.64Å; Y83-Y252 AromaticContact CE2-CE2 3.88Å; Y83-Y252 HydrophobicContact CE2-CE2 3.88Å; Y83-Y252 AromaticContact CG-CD2 3.87Å; Y83-Y252 HydrophobicContact CG-CD2 3.87Å; Y83-Y252 AromaticContact CZ-CD2 3.54Å; Y83-Y252 AromaticContact CZ-CE2 3.42Å; Y83-Y252 VanDerWaalsContact CZ-CE2 3.42Å; A97-Y252 HydrophobicContact CB-CE2 4.1Å; A97-Y252 WeakPolarHBondContact CB-OH 3.47Å; A97-Y252 PolarHBondContact N-OH 3.04Å; G241-Y252 WeakPolarHBondContact CA-OH 3.17Å; F244-Y252 HydrophobicContact CB-CD2 3.38Å; F244-Y252 HydrophobicContact CB-CE2 3.94Å; F244-Y252 HydrophobicContact CB-CG 3.93Å; F244-Y252 HydrophobicContact CD2-CD2 4.17Å; F244-Y252 AromaticContact CD2-CE2 3.86Å; F244-Y252 HydrophobicContact CD2-CE2 3.86Å; F244-Y252 AromaticContact CG-CD2 3.99Å; F244-Y252 HydrophobicContact CG-CD2 3.99Å; F244-Y252 HydrophobicContact CG-CE2 4.17Å; L245-Y252 HydrophobicContact CD2-CD1 3.53Å; L245-Y252 HydrophobicContact CD2-CE1 4.19Å; L245-Y252 HydrophobicContact CD2-CG 4.28Å; L245-Y252 HydrophobicContact CG-CD1 3.85Å; L245-Y252 HydrophobicContact CG-CE1 4.21Å; L245-Y252 HydrophobicContact CG-CG 4.46Å; N248-Y252 PolarHBondContact O-N 3Å; Y252-S254 PolarHBondContact O-N 3.16Å; Y252-R255 PolarHBondContact O-N 3.18Å; Y252-A256 HydrophobicContact CD2-CB 4.23Å; Y252-A256 HydrophobicContact CE1-CB 4.37Å; Y252-A256 HydrophobicContact CE2-CB 4.03Å; Y252-A256 WeakPolarHBondContact O-CB 3.36Å; Y252-A256 PolarHBondContact O-N 3.01Å
253	L	92.5	Very high	89.1	Confident	101 Å²	101	62.4 Å²	62.4	53%	0.529	34%	0.341	S	S	.	.	H	α-helix	trans	-64.4	-39.1	-175.5	-70	175.1	0	0	0	112.7	L245 P249	L245-L253 HydrophobicContact CD2-CD2 4.49Å; L245-L253 HydrophobicContact CD2-CG 4.34Å; P249-L253 WeakPolarHBondContact O-CB 3.31Å; P249-L253 VanDerWaalsContact O-CG 3.32Å; P249-L253 WeakPolarHBondContact O-CG 3.39Å; P249-L253 PolarHBondContact O-N 3.09Å
254	S	90.4	Very high	88.4	Confident	60 Å²	60	65.2 Å²	65.2	42%	0.42	35%	0.35	S	S	.	.	H	α-helix	trans	-71	-30.7	179.8	61.3	0	0	0	0	113.4	V250 G251 Y252 D258	V250-S254 VanDerWaalsContact O-CB 3.25Å; V250-S254 WeakPolarHBondContact O-CB 3.27Å; V250-S254 PolarHBondContact O-N 3.09Å; V250-S254 PolarHBondContact O-OG 3.48Å; G251-S254 PolarHBondContact O-OG 3.33Å; Y252-S254 PolarHBondContact O-N 3.16Å; S254-D258 VanDerWaalsContact O-CA 3.28Å; S254-D258 WeakPolarHBondContact O-CA 3.43Å; S254-D258 WeakPolarHBondContact O-CB 3.45Å
255	R	90.8	Very high	87.8	Confident	76 Å²	76	66 Å²	66	29%	0.287	35%	0.354	S	S	.	.	H	α-helix	trans	-91	-51.5	-179.4	-67.8	-66.9	-169.8	176.3	5.5	113	Y83 V94 G251 Y252 F257 D258	Y83-R255 HydrophobicContact CD1-CB 4.01Å; V94-R255 CarbonylContact C-O 3.25Å; V94-R255 VanDerWaalsContact CA-O 3.3Å; V94-R255 WeakPolarHBondContact CA-O 3.42Å; G251-R255 VanDerWaalsContact O-CB 3.29Å; G251-R255 WeakPolarHBondContact O-CB 3.42Å; G251-R255 VanDerWaalsContact O-CG 3.26Å; G251-R255 WeakPolarHBondContact O-CG 3.38Å; G251-R255 PolarHBondContact O-N 3.41Å; G251-R255 VanDerWaalsContact O-N 3.11Å; Y252-R255 PolarHBondContact O-N 3.18Å; R255-F257 PolarHBondContact O-N 3.12Å; R255-D258 PolarHBondContact O-N 2.88Å
256	A	88.3	Confident	87.3	Confident	0 Å²	0	69.9 Å²	69.9	0%	0	37%	0.37	C	S	.	.	H	α-helix	trans	-59.6	-33.8	-175.7	0	0	0	0	0	113	Y83 P96 Y252	Y83-A256 HydrophobicContact CD1-CB 4.22Å; Y83-A256 HydrophobicContact CE1-CB 3.87Å; P96-A256 HydrophobicContact CB-CB 4.2Å; P96-A256 HydrophobicContact CG-CB 4.47Å; P96-A256 WeakPolarHBondContact CG-O 3.29Å; Y252-A256 HydrophobicContact CD2-CB 4.23Å; Y252-A256 HydrophobicContact CE1-CB 4.37Å; Y252-A256 HydrophobicContact CE2-CB 4.03Å; Y252-A256 WeakPolarHBondContact O-CB 3.36Å; Y252-A256 PolarHBondContact O-N 3.01Å
257	F	84.6	Confident	86.8	Confident	47 Å²	47	67.8 Å²	67.8	21%	0.206	35%	0.352	C	S	.	.	T	Hydrogen-bonded Turn	trans	-124.7	45.2	179.2	-60.2	-85.1	0	0	0	110.3	P96 V200 M204 L207 R255 L259	P96-F257 HydrophobicContact CB-CE1 4.41Å; P96-F257 HydrophobicContact CB-CE2 4.16Å; P96-F257 HydrophobicContact CB-CZ 3.86Å; P96-F257 HydrophobicContact CG-CD1 4.29Å; P96-F257 HydrophobicContact CG-CE1 3.74Å; P96-F257 HydrophobicContact CG-CE2 4.22Å; P96-F257 HydrophobicContact CG-CZ 3.7Å; V200-F257 HydrophobicContact CG1-CE1 4.13Å; M204-F257 HydrophobicContact CB-CD1 3.92Å; M204-F257 HydrophobicContact CB-CE1 4.36Å; L207-F257 HydrophobicContact CD1-CD1 4.38Å; R255-F257 PolarHBondContact O-N 3.12Å; F257-L259 VanDerWaalsContact C-N 3.3Å; F257-L259 WeakPolarHBondContact O-CG 3.46Å; F257-L259 PolarHBondContact O-N 3.19Å
258	D	82.8	Confident	86.6	Confident	39 Å²	39	63.4 Å²	63.4	21%	0.209	33%	0.328	C	S	.	.			trans	-59.3	85.1	-177.7	-173.1	-1.1	0	0	0	112.9	S254 R255 G260 R261	S254-D258 VanDerWaalsContact O-CA 3.28Å; S254-D258 WeakPolarHBondContact O-CA 3.43Å; S254-D258 WeakPolarHBondContact O-CB 3.45Å; R255-D258 PolarHBondContact O-N 2.88Å; D258-G260 PolarHBondContact O-N 3.42Å; D258-G260 WeakPolarHBondContact OD1-CA 3.44Å; D258-G260 PolarHBondContact OD1-N 3.42Å; D258-G260 VanDerWaalsContact OD1-N 3.08Å; D258-R261 HydrophobicContact CB-CB 4.33Å; D258-R261 PolarHBondContact O-N 2.98Å; D258-R261 PolarHBondContact OD1-N 2.94Å; D258-R261 WeakPolarHBondContact OD2-CB 3.01Å
259	L	75.8	Confident	86.5	Confident	145 Å²	145	61.6 Å²	61.6	76%	0.759	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.3	-15.3	175.7	-62	179.9	0	0	0	112.1	F257	F257-L259 VanDerWaalsContact C-N 3.3Å; F257-L259 WeakPolarHBondContact O-CG 3.46Å; F257-L259 PolarHBondContact O-N 3.19Å
260	G	68.6	Low	86.5	Confident	60 Å²	60	58.5 Å²	58.5	62%	0.619	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	-13.5	178.8	0	0	0	0	0	113.3	D258 Q262	D258-G260 PolarHBondContact O-N 3.42Å; D258-G260 WeakPolarHBondContact OD1-CA 3.44Å; D258-G260 PolarHBondContact OD1-N 3.42Å; D258-G260 VanDerWaalsContact OD1-N 3.08Å; G260-Q262 PolarHBondContact O-N 3.27Å
261	R	78.3	Confident	86.5	Confident	87 Å²	87	55.1 Å²	55.1	33%	0.328	27%	0.274	S	S	.	.			trans	-55.2	125.1	-173.2	-163.9	169.7	-173.8	-178.6	4.7	111.8	D258 F263	D258-R261 HydrophobicContact CB-CB 4.33Å; D258-R261 PolarHBondContact O-N 2.98Å; D258-R261 PolarHBondContact OD1-N 2.94Å; D258-R261 WeakPolarHBondContact OD2-CB 3.01Å; R261-F263 HydrophobicContact CG-CE1 4.42Å
262	Q	76.1	Confident	86.6	Confident	102 Å²	102	58 Å²	58	48%	0.477	28%	0.284	S	S	.	.			trans	-100.9	110.6	172	-59.3	-162.6	-14.7	0	0	110.1	G260	G260-Q262 PolarHBondContact O-N 3.27Å
263	F	81.1	Confident	86.5	Confident	55 Å²	55	61.6 Å²	61.6	24%	0.241	30%	0.3	C	S	.	.			trans	-74.6	144.5	173.4	-71.4	-58.4	0	0	0	111.3	R261 S353 H355 F358	R261-F263 HydrophobicContact CG-CE1 4.42Å; F263-S353 WeakPolarHBondContact CB-OG 3.41Å; F263-H355 VanDerWaalsContact CB-CE1 3.47Å; F263-H355 WeakPolarHBondContact CB-CE1 3.19Å; F263-H355 WeakPolarHBondContact CB-NE2 3.28Å; F263-H355 AromaticContact CD1-CE1 3.12Å; F263-H355 WeakPolarHBondContact CD1-CE1 3.33Å; F263-H355 AromaticContact CD1-ND1 3.56Å; F263-H355 AromaticContact CD1-NE2 3.98Å; F263-H355 AromaticContact CE1-CE1 3.96Å; F263-H355 AromaticContact CE1-ND1 3.97Å; F263-H355 AromaticContact CG-CE1 3.47Å; F263-H355 VanDerWaalsContact CG-CE1 3.47Å; F263-H355 WeakPolarHBondContact CG-CE1 3.3Å; F263-H355 AromaticContact CG-NE2 3.89Å; F263-F358 HydrophobicContact CE1-CZ 4.27Å; F263-F358 HydrophobicContact CE2-CE2 4.23Å; F263-F358 HydrophobicContact CE2-CZ 4.21Å; F263-F358 HydrophobicContact CZ-CE2 4.35Å; F263-F358 AromaticContact CZ-CZ 3.86Å; F263-F358 HydrophobicContact CZ-CZ 3.86Å
264	M	81.4	Confident	86.6	Confident	108 Å²	108	58.2 Å²	58.2	53%	0.532	28%	0.282	S	S	.	.			trans	-69	133.6	-175.7	-57.9	-68	-74.2	0	0	111.2	K266 W267	M264-K266 HydrophobicContact CB-CG 4.05Å; M264-K266 PolarHBondContact O-N 3.3Å; M264-K266 VanDerWaalsContact O-N 3.1Å; M264-W267 PolarHBondContact O-N 3.48Å
265	F	85.8	Confident	86.8	Confident	19 Å²	19	58.1 Å²	58.1	8%	0.083	28%	0.28	C	S	.	.	G	3₁₀ helix	trans	-58.5	-27.7	179.3	-178.1	-113.7	0	0	0	113.3	W267 T268 R272 L274 E276 F279	F265-W267 PolarHBondContact O-N 3.48Å; F265-T268 HydrophobicContact CD2-CG2 3.88Å; F265-T268 HydrophobicContact CE2-CG2 4Å; F265-T268 VanDerWaalsContact O-CG2 3.29Å; F265-T268 WeakPolarHBondContact O-CG2 3.37Å; F265-T268 PolarHBondContact O-N 2.87Å; F265-R272 VanDerWaalsContact CE1-NH1 3.32Å; F265-R272 PolarHBondContact O-NH1 2.9Å; F265-L274 WeakPolarHBondContact CZ-O 3.25Å; F265-E276 HydrophobicContact CB-CG 3.85Å; F265-E276 HydrophobicContact CD1-CB 3.76Å; F265-E276 HydrophobicContact CD1-CG 3.93Å; F265-E276 HydrophobicContact CE1-CB 4.13Å; F265-E276 HydrophobicContact CG-CB 4.12Å; F265-E276 HydrophobicContact CG-CG 3.95Å; F265-F279 HydrophobicContact CB-CD1 4.14Å; F265-F279 HydrophobicContact CB-CE1 4.29Å; F265-F279 HydrophobicContact CD2-CB 3.86Å; F265-F279 AromaticContact CD2-CD1 3.68Å; F265-F279 HydrophobicContact CD2-CD1 3.68Å; F265-F279 AromaticContact CD2-CD2 3.73Å; F265-F279 HydrophobicContact CD2-CD2 3.73Å; F265-F279 HydrophobicContact CD2-CE1 4.08Å; F265-F279 HydrophobicContact CD2-CE2 4.09Å; F265-F279 AromaticContact CD2-CG 3.48Å; F265-F279 HydrophobicContact CD2-CG 3.48Å; F265-F279 VanDerWaalsContact CD2-CG 3.48Å; F265-F279 HydrophobicContact CD2-CZ 4.26Å; F265-F279 HydrophobicContact CE2-CB 4.07Å; F265-F279 AromaticContact CE2-CD2 3.97Å; F265-F279 HydrophobicContact CE2-CD2 3.97Å; F265-F279 AromaticContact CE2-CG 3.99Å; F265-F279 HydrophobicContact CE2-CG 3.99Å; F265-F279 HydrophobicContact CG-CD1 4.34Å; F265-F279 HydrophobicContact CG-CG 4.48Å
266	K	85.3	Confident	87	Confident	115 Å²	115	59.1 Å²	59.1	50%	0.5	29%	0.288	S	S	.	.	G	3₁₀ helix	trans	-63	-25	177.3	73.2	-176.7	-176.5	179.2	0	114.5	M264	M264-K266 HydrophobicContact CB-CG 4.05Å; M264-K266 PolarHBondContact O-N 3.3Å; M264-K266 VanDerWaalsContact O-N 3.1Å
267	W	87.8	Confident	87.2	Confident	94 Å²	94	67.5 Å²	67.5	36%	0.356	32%	0.32	S	S	.	.	G	3₁₀ helix	trans	-101.1	-4	-174.9	-61.9	130	0	0	0	113.3	M264 F265 H355 Y397	M264-W267 PolarHBondContact O-N 3.48Å; F265-W267 PolarHBondContact O-N 3.48Å; W267-H355 VanDerWaalsContact CB-CD2 3.48Å; W267-H355 WeakPolarHBondContact CB-CD2 3.49Å; W267-H355 VanDerWaalsContact CB-NE2 3.33Å; W267-H355 WeakPolarHBondContact CB-NE2 3.33Å; W267-H355 PolarHBondContact O-CD2 3.29Å; W267-Y397 AromaticContact CE3-CE2 3.94Å; W267-Y397 HydrophobicContact CE3-CE2 3.94Å; W267-Y397 WeakPolarHBondContact CH2-OH 3.41Å; W267-Y397 AromaticContact CZ3-CE2 3.53Å; W267-Y397 HydrophobicContact CZ3-CE2 3.53Å; W267-Y397 AromaticContact CZ3-CZ 3.68Å; W267-Y397 WeakPolarHBondContact CZ3-OH 3.39Å
268	T	92.5	Very high	87.7	Confident	0 Å²	0	67.5 Å²	67.5	0%	0	32%	0.322	C	S	.	.			trans	-72.4	133.7	-177.2	-161.3	0	0	0	0	111.3	F265 N270 F279 L354 S399	F265-T268 HydrophobicContact CD2-CG2 3.88Å; F265-T268 HydrophobicContact CE2-CG2 4Å; F265-T268 VanDerWaalsContact O-CG2 3.29Å; F265-T268 WeakPolarHBondContact O-CG2 3.37Å; F265-T268 PolarHBondContact O-N 2.87Å; T268-N270 WeakPolarHBondContact CB-O 3.24Å; T268-N270 WeakPolarHBondContact CG2-O 3.3Å; T268-N270 PolarHBondContact OG1-O 3.46Å; T268-N270 PolarHBondContact OG1-OD1 3Å; T268-F279 HydrophobicContact CG2-CE2 4.01Å; T268-F279 HydrophobicContact CG2-CZ 4.26Å; T268-L354 CarbonylContact C-O 3.53Å; T268-S399 WeakPolarHBondContact O-CB 3.07Å; T268-S399 PolarHBondContact O-OG 3Å
269	V	94.9	Very high	88.1	Confident	0 Å²	0	65.6 Å²	65.6	0%	0	31%	0.312	C	S	.	.	S	Bend	trans	-87.4	-34.6	172	-176.6	0	0	0	0	109.9	L354 Y356 W394 S404 L407	V269-L354 WeakPolarHBondContact CB-O 3.46Å; V269-L354 WeakPolarHBondContact CG2-O 3.07Å; V269-L354 PolarHBondContact N-O 3.43Å; V269-Y356 HydrophobicContact CG2-CD1 3.48Å; V269-Y356 VanDerWaalsContact CG2-CD1 3.48Å; V269-Y356 HydrophobicContact CG2-CD2 4.24Å; V269-Y356 HydrophobicContact CG2-CE1 3.46Å; V269-Y356 VanDerWaalsContact CG2-CE1 3.46Å; V269-Y356 HydrophobicContact CG2-CE2 4.11Å; V269-Y356 HydrophobicContact CG2-CG 3.97Å; V269-W394 HydrophobicContact CB-CE3 4.27Å; V269-W394 HydrophobicContact CB-CZ3 4.18Å; V269-W394 HydrophobicContact CG1-CD2 4.18Å; V269-W394 HydrophobicContact CG1-CE3 4.08Å; V269-W394 HydrophobicContact CG1-CZ3 4.42Å; V269-W394 HydrophobicContact CG2-CE3 3.82Å; V269-W394 HydrophobicContact CG2-CZ3 3.78Å; V269-S404 VanDerWaalsContact O-CB 3.3Å; V269-S404 WeakPolarHBondContact O-CB 3.44Å; V269-S404 PolarHBondContact O-OG 2.92Å; V269-L407 HydrophobicContact CG1-CD2 3.82Å
270	N	95.4	Very high	88.9	Confident	1 Å²	1	61.7 Å²	61.7	1%	0.005	29%	0.291	C	S	.	.	S	Bend	trans	-101	155.6	179	71.7	-29.5	0	0	0	111.7	T268 R272 S351 L354 S404 L407	T268-N270 WeakPolarHBondContact CB-O 3.24Å; T268-N270 WeakPolarHBondContact CG2-O 3.3Å; T268-N270 PolarHBondContact OG1-O 3.46Å; T268-N270 PolarHBondContact OG1-OD1 3Å; N270-R272 PolarHBondContact O-N 3.49Å; N270-S351 PolarHBondContact ND2-O 3.49Å; N270-L354 HydrophobicContact CB-CB 4.39Å; N270-L354 HydrophobicContact CB-CD1 4.09Å; N270-L354 HydrophobicContact CB-CG 4.4Å; N270-L354 WeakPolarHBondContact OD1-CB 3.49Å; N270-L354 PolarHBondContact OD1-N 3.2Å; N270-S404 WeakPolarHBondContact CA-OG 3.29Å; N270-L407 HydrophobicContact CB-CD2 4.21Å
271	W	95.6	Very high	90.1	Very high	39 Å²	39	61.2 Å²	61.2	15%	0.148	27%	0.274	C	S	.	.	S	Bend	trans	62.5	15.2	-179	-49.5	107.3	0	0	0	115.9	F273 L274 F279 F284 L288 S351 S404 H408	W271-F273 HydrophobicContact CE3-CE2 4.18Å; W271-F273 AromaticContact CE3-CZ 3.74Å; W271-F273 HydrophobicContact CE3-CZ 3.74Å; W271-F273 HydrophobicContact CZ3-CZ 4.09Å; W271-F273 PolarHBondContact O-N 3.19Å; W271-L274 HydrophobicContact CB-CD1 4.11Å; W271-L274 HydrophobicContact CB-CG 4.39Å; W271-L274 HydrophobicContact CD2-CD1 4.21Å; W271-L274 HydrophobicContact CE3-CD1 3.62Å; W271-L274 HydrophobicContact CE3-CG 4.23Å; W271-L274 HydrophobicContact CG-CD1 4.45Å; W271-L274 HydrophobicContact CZ3-CD1 4.4Å; W271-L274 WeakPolarHBondContact O-CB 3.47Å; W271-L274 PolarHBondContact O-N 3.42Å; W271-F279 HydrophobicContact CB-CD2 3.91Å; W271-F279 HydrophobicContact CB-CE2 4.09Å; W271-F284 AromaticContact CD2-CZ 3.96Å; W271-F284 HydrophobicContact CD2-CZ 3.96Å; W271-F284 HydrophobicContact CE3-CZ 4.02Å; W271-F284 HydrophobicContact CG-CZ 4.46Å; W271-F284 HydrophobicContact CZ2-CZ 4.46Å; W271-F284 HydrophobicContact CZ3-CZ 4.29Å; W271-L288 HydrophobicContact CH2-CD2 4.04Å; W271-L288 HydrophobicContact CZ2-CD2 3.51Å; W271-S351 PolarHBondContact NE1-O 3.02Å; W271-S404 PolarHBondContact N-OG 3.34Å; W271-H408 AromaticContact CD2-CE1 3.65Å; W271-H408 AromaticContact CD2-NE2 3.36Å; W271-H408 AromaticContact CE2-CE1 3.32Å; W271-H408 AromaticContact CE2-NE2 3.52Å; W271-H408 AromaticContact CE3-CE1 3.9Å; W271-H408 AromaticContact CE3-NE2 3.62Å; W271-H408 AromaticContact CG-NE2 3.76Å; W271-H408 AromaticContact CH2-CE1 3.58Å; W271-H408 AromaticContact CZ2-CE1 3.3Å; W271-H408 WeakPolarHBondContact CZ2-CE1 3.16Å; W271-H408 AromaticContact CZ2-NE2 3.93Å; W271-H408 AromaticContact CZ3-CE1 3.86Å; W271-H408 PolarHBondContact N-NE2 3.37Å; W271-H408 AromaticContact NE1-CE1 3.85Å; W271-H408 AromaticContact NE1-NE2 3.91Å
272	R	94.8	Very high	90.7	Very high	65 Å²	65	66.7 Å²	66.7	25%	0.245	30%	0.295	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61	-27.5	-179.8	-173.4	61.8	169.1	162.2	7.1	113.2	F265 N270 L274 S399 N401 S404	F265-R272 VanDerWaalsContact CE1-NH1 3.32Å; F265-R272 PolarHBondContact O-NH1 2.9Å; N270-R272 PolarHBondContact O-N 3.49Å; R272-L274 PolarHBondContact O-N 3.02Å; R272-S399 WeakPolarHBondContact CD-OG 3.49Å; R272-S399 WeakPolarHBondContact CG-OG 3.37Å; R272-S399 PolarHBondContact NE-O 3.16Å; R272-N401 PolarHBondContact O-OD1 3.16Å; R272-S404 PolarHBondContact N-OG 2.87Å
273	F	94.3	Very high	91.6	Very high	80 Å²	80	70.3 Å²	70.3	35%	0.351	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.6	-11.1	176.2	58.7	-102.5	0	0	0	113.8	W271 N401 A405 H408	W271-F273 HydrophobicContact CE3-CE2 4.18Å; W271-F273 AromaticContact CE3-CZ 3.74Å; W271-F273 HydrophobicContact CE3-CZ 3.74Å; W271-F273 HydrophobicContact CZ3-CZ 4.09Å; W271-F273 PolarHBondContact O-N 3.19Å; F273-N401 HydrophobicContact CB-CB 4.03Å; F273-A405 HydrophobicContact CD1-CB 4.18Å; F273-H408 AromaticContact CE1-CD2 3.54Å; F273-H408 AromaticContact CZ-CD2 3.96Å
274	L	94.7	Very high	92.3	Very high	30 Å²	30	69.1 Å²	69.1	16%	0.157	30%	0.3	C	S	.	.	S	Bend	trans	-84.4	149.2	173.9	-63.2	-175.1	0	0	0	110.4	F265 W271 R272 L278 F284	F265-L274 WeakPolarHBondContact CZ-O 3.25Å; W271-L274 HydrophobicContact CB-CD1 4.11Å; W271-L274 HydrophobicContact CB-CG 4.39Å; W271-L274 HydrophobicContact CD2-CD1 4.21Å; W271-L274 HydrophobicContact CE3-CD1 3.62Å; W271-L274 HydrophobicContact CE3-CG 4.23Å; W271-L274 HydrophobicContact CG-CD1 4.45Å; W271-L274 HydrophobicContact CZ3-CD1 4.4Å; W271-L274 WeakPolarHBondContact O-CB 3.47Å; W271-L274 PolarHBondContact O-N 3.42Å; R272-L274 PolarHBondContact O-N 3.02Å; L274-L278 HydrophobicContact CD1-CD2 4.3Å; L274-L278 HydrophobicContact CD2-CD2 4.13Å; L274-F284 HydrophobicContact CD1-CE1 4.04Å; L274-F284 HydrophobicContact CD1-CE2 3.95Å; L274-F284 HydrophobicContact CD1-CZ 3.5Å; L274-F284 VanDerWaalsContact CD1-CZ 3.5Å
275	P	94.6	Very high	92.8	Very high	58 Å²	58	67.6 Å²	67.6	38%	0.377	29%	0.292	S	S	.	.			trans	-67.4	147	170.9	30.2	-34.8	0	0	0	111	W277 L278 F279	P275-W277 VanDerWaalsContact C-N 3.28Å; P275-W277 HydrophobicContact CB-CG 4.46Å; P275-W277 HydrophobicContact CG-CD2 4.46Å; P275-W277 HydrophobicContact CG-CZ2 4.01Å; P275-W277 PolarHBondContact O-N 2.9Å; P275-L278 HydrophobicContact CG-CB 3.94Å; P275-L278 PolarHBondContact O-N 2.89Å; P275-F279 PolarHBondContact O-N 3.36Å; P275-F279 VanDerWaalsContact O-N 3.12Å
276	E	93.9	Very high	93.2	Very high	98 Å²	98	71.8 Å²	71.8	46%	0.458	31%	0.314	S	S	.	.	H	α-helix	trans	-58.5	-37	-174.5	-177.7	164.5	-164.7	0	0	113.1	F265 L278 F279 L280	F265-E276 HydrophobicContact CB-CG 3.85Å; F265-E276 HydrophobicContact CD1-CB 3.76Å; F265-E276 HydrophobicContact CD1-CG 3.93Å; F265-E276 HydrophobicContact CE1-CB 4.13Å; F265-E276 HydrophobicContact CG-CB 4.12Å; F265-E276 HydrophobicContact CG-CG 3.95Å; E276-L278 VanDerWaalsContact C-N 3.26Å; E276-L278 PolarHBondContact O-N 2.89Å; E276-F279 WeakPolarHBondContact O-CB 3.38Å; E276-F279 PolarHBondContact O-N 3.34Å; E276-L280 HydrophobicContact CG-CD1 3.82Å; E276-L280 HydrophobicContact CG-CG 4.23Å; E276-L280 WeakPolarHBondContact O-CG 3.32Å; E276-L280 PolarHBondContact O-N 3.29Å
277	W	93.9	Very high	93.7	Very high	175 Å²	175	70.9 Å²	70.9	66%	0.663	32%	0.318	S	S	*	.	H	α-helix	trans	-61.1	-34.4	177.5	69.2	-101.5	0	0	0	112.6	P275 N281	P275-W277 VanDerWaalsContact C-N 3.28Å; P275-W277 HydrophobicContact CB-CG 4.46Å; P275-W277 HydrophobicContact CG-CD2 4.46Å; P275-W277 HydrophobicContact CG-CZ2 4.01Å; P275-W277 PolarHBondContact O-N 2.9Å; W277-N281 WeakPolarHBondContact O-CB 3.11Å; W277-N281 PolarHBondContact O-N 3Å
278	L	93.6	Very high	94.1	Very high	47 Å²	47	66.9 Å²	66.9	25%	0.246	30%	0.304	C	S	.	.	H	α-helix	trans	-77.6	-39.8	177.4	-178.7	60.4	0	0	0	110.4	L274 P275 E276 L280 N281 F284	L274-L278 HydrophobicContact CD1-CD2 4.3Å; L274-L278 HydrophobicContact CD2-CD2 4.13Å; P275-L278 HydrophobicContact CG-CB 3.94Å; P275-L278 PolarHBondContact O-N 2.89Å; E276-L278 VanDerWaalsContact C-N 3.26Å; E276-L278 PolarHBondContact O-N 2.89Å; L278-L280 VanDerWaalsContact C-N 3.28Å; L278-L280 PolarHBondContact O-N 3.37Å; L278-N281 HydrophobicContact CD1-CB 4.49Å; L278-N281 WeakPolarHBondContact O-CB 3.47Å; L278-N281 PolarHBondContact O-N 3.37Å; L278-N281 VanDerWaalsContact O-N 3.1Å; L278-F284 HydrophobicContact CD1-CB 4.27Å; L278-F284 WeakPolarHBondContact O-CB 3.43Å; L278-F284 WeakPolarHBondContact O-CD1 3.47Å
279	F	92.8	Very high	94.3	Very high	0 Å²	0	70.7 Å²	70.7	0%	0	32%	0.324	C	S	.	.	H	α-helix	trans	-60.2	-36.8	175.8	-178.7	-89.2	0	0	0	112.8	F265 T268 W271 P275 E276 N281 R352	F265-F279 HydrophobicContact CB-CD1 4.14Å; F265-F279 HydrophobicContact CB-CE1 4.29Å; F265-F279 HydrophobicContact CD2-CB 3.86Å; F265-F279 AromaticContact CD2-CD1 3.68Å; F265-F279 HydrophobicContact CD2-CD1 3.68Å; F265-F279 AromaticContact CD2-CD2 3.73Å; F265-F279 HydrophobicContact CD2-CD2 3.73Å; F265-F279 HydrophobicContact CD2-CE1 4.08Å; F265-F279 HydrophobicContact CD2-CE2 4.09Å; F265-F279 AromaticContact CD2-CG 3.48Å; F265-F279 HydrophobicContact CD2-CG 3.48Å; F265-F279 VanDerWaalsContact CD2-CG 3.48Å; F265-F279 HydrophobicContact CD2-CZ 4.26Å; F265-F279 HydrophobicContact CE2-CB 4.07Å; F265-F279 AromaticContact CE2-CD2 3.97Å; F265-F279 HydrophobicContact CE2-CD2 3.97Å; F265-F279 AromaticContact CE2-CG 3.99Å; F265-F279 HydrophobicContact CE2-CG 3.99Å; F265-F279 HydrophobicContact CG-CD1 4.34Å; F265-F279 HydrophobicContact CG-CG 4.48Å; T268-F279 HydrophobicContact CG2-CE2 4.01Å; T268-F279 HydrophobicContact CG2-CZ 4.26Å; W271-F279 HydrophobicContact CB-CD2 3.91Å; W271-F279 HydrophobicContact CB-CE2 4.09Å; P275-F279 PolarHBondContact O-N 3.36Å; P275-F279 VanDerWaalsContact O-N 3.12Å; E276-F279 WeakPolarHBondContact O-CB 3.38Å; E276-F279 PolarHBondContact O-N 3.34Å; F279-N281 VanDerWaalsContact C-N 3.34Å; F279-R352 HydrophobicContact CE2-CG 4.4Å; F279-R352 WeakPolarHBondContact CE2-O 3.45Å; F279-R352 HydrophobicContact CZ-CG 4.48Å; F279-R352 WeakPolarHBondContact CZ-O 3.33Å; F279-R352 WeakPolarHBondContact O-CD 3.36Å; F279-R352 PolarHBondContact O-NH1 2.93Å
280	L	91.9	Very high	94.4	Very high	62 Å²	62	73.6 Å²	73.6	33%	0.325	35%	0.348	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.5	-6.3	177.5	-63.5	177.3	0	0	0	113.3	E276 L278 R282	E276-L280 HydrophobicContact CG-CD1 3.82Å; E276-L280 HydrophobicContact CG-CG 4.23Å; E276-L280 WeakPolarHBondContact O-CG 3.32Å; E276-L280 PolarHBondContact O-N 3.29Å; L278-L280 VanDerWaalsContact C-N 3.28Å; L278-L280 PolarHBondContact O-N 3.37Å; L280-R282 PolarHBondContact O-N 3.25Å
281	N	93.4	Very high	94.5	Very high	50 Å²	50	75 Å²	75	27%	0.267	36%	0.359	S	S	.	.			trans	-68.2	130.6	-177	-169.3	-62.6	0	0	0	111.7	W277 L278 F279 Y283 F284 H285	W277-N281 WeakPolarHBondContact O-CB 3.11Å; W277-N281 PolarHBondContact O-N 3Å; L278-N281 HydrophobicContact CD1-CB 4.49Å; L278-N281 WeakPolarHBondContact O-CB 3.47Å; L278-N281 PolarHBondContact O-N 3.37Å; L278-N281 VanDerWaalsContact O-N 3.1Å; F279-N281 VanDerWaalsContact C-N 3.34Å; N281-Y283 PolarHBondContact O-N 3.41Å; N281-Y283 WeakPolarHBondContact OD1-CA 3.5Å; N281-Y283 VanDerWaalsContact OD1-CB 3.26Å; N281-Y283 WeakPolarHBondContact OD1-CB 3.24Å; N281-Y283 VanDerWaalsContact OD1-CD2 3.27Å; N281-Y283 WeakPolarHBondContact OD1-CD2 3.49Å; N281-Y283 PolarHBondContact OD1-N 2.81Å; N281-F284 HydrophobicContact CB-CB 4.1Å; N281-F284 WeakPolarHBondContact O-CB 3.48Å; N281-F284 PolarHBondContact O-N 3.18Å; N281-F284 PolarHBondContact OD1-N 3.46Å; N281-H285 PolarHBondContact O-N 3.03Å
282	R	91.4	Very high	94.7	Very high	202 Å²	202	74.4 Å²	74.4	76%	0.762	36%	0.358	S	S	*	.	H	α-helix	trans	-64.3	-36.7	179.7	-67.4	-176.4	179.5	179.1	-0.3	112.9	L280 F284 H285 L286	L280-R282 PolarHBondContact O-N 3.25Å; R282-F284 VanDerWaalsContact C-N 3.34Å; R282-H285 WeakPolarHBondContact O-CB 3.36Å; R282-H285 PolarHBondContact O-N 3.44Å; R282-L286 WeakPolarHBondContact O-CG 3.26Å; R282-L286 PolarHBondContact O-N 3.4Å
283	Y	95.4	Very high	94.8	Very high	178 Å²	178	76 Å²	76	70%	0.698	37%	0.371	S	S	*	.	H	α-helix	trans	-65.9	-38.8	176.3	-58.5	-76.6	0	0	0	111.3	N281 H285 L286 V287	N281-Y283 PolarHBondContact O-N 3.41Å; N281-Y283 WeakPolarHBondContact OD1-CA 3.5Å; N281-Y283 VanDerWaalsContact OD1-CB 3.26Å; N281-Y283 WeakPolarHBondContact OD1-CB 3.24Å; N281-Y283 VanDerWaalsContact OD1-CD2 3.27Å; N281-Y283 WeakPolarHBondContact OD1-CD2 3.49Å; N281-Y283 PolarHBondContact OD1-N 2.81Å; Y283-H285 VanDerWaalsContact C-N 3.32Å; Y283-H285 PolarHBondContact O-N 3.2Å; Y283-L286 PolarHBondContact O-N 2.86Å; Y283-V287 VanDerWaalsContact O-CG2 3.32Å; Y283-V287 WeakPolarHBondContact O-CG2 3.46Å; Y283-V287 PolarHBondContact O-N 2.87Å
284	F	94.2	Very high	95	Very high	30 Å²	30	76.9 Å²	76.9	13%	0.132	38%	0.379	C	S	.	.	H	α-helix	trans	-60	-43.7	173.9	-179.6	-115.2	0	0	0	111.3	W271 L274 L278 N281 R282 L286 V287 L288 R352	W271-F284 AromaticContact CD2-CZ 3.96Å; W271-F284 HydrophobicContact CD2-CZ 3.96Å; W271-F284 HydrophobicContact CE3-CZ 4.02Å; W271-F284 HydrophobicContact CG-CZ 4.46Å; W271-F284 HydrophobicContact CZ2-CZ 4.46Å; W271-F284 HydrophobicContact CZ3-CZ 4.29Å; L274-F284 HydrophobicContact CD1-CE1 4.04Å; L274-F284 HydrophobicContact CD1-CE2 3.95Å; L274-F284 HydrophobicContact CD1-CZ 3.5Å; L274-F284 VanDerWaalsContact CD1-CZ 3.5Å; L278-F284 HydrophobicContact CD1-CB 4.27Å; L278-F284 WeakPolarHBondContact O-CB 3.43Å; L278-F284 WeakPolarHBondContact O-CD1 3.47Å; N281-F284 HydrophobicContact CB-CB 4.1Å; N281-F284 WeakPolarHBondContact O-CB 3.48Å; N281-F284 PolarHBondContact O-N 3.18Å; N281-F284 PolarHBondContact OD1-N 3.46Å; R282-F284 VanDerWaalsContact C-N 3.34Å; F284-L286 PolarHBondContact O-N 3.39Å; F284-V287 PolarHBondContact O-N 3.5Å; F284-L288 HydrophobicContact CD1-CD1 4.04Å; F284-L288 HydrophobicContact CE1-CD1 3.54Å; F284-L288 HydrophobicContact CE1-CG 4.31Å; F284-L288 HydrophobicContact CE2-CD1 4.35Å; F284-L288 HydrophobicContact CE2-CD2 4.42Å; F284-L288 HydrophobicContact CE2-CG 4.27Å; F284-L288 HydrophobicContact CZ-CD1 3.71Å; F284-L288 HydrophobicContact CZ-CD2 4.25Å; F284-L288 HydrophobicContact CZ-CG 4.09Å; F284-L288 WeakPolarHBondContact O-CG 3.48Å; F284-L288 PolarHBondContact O-N 2.77Å; F284-R352 HydrophobicContact CD1-CG 4.4Å; F284-R352 HydrophobicContact CE1-CG 4.26Å
285	H	91.8	Very high	95.1	Very high	77 Å²	77	76.7 Å²	76.7	36%	0.356	38%	0.379	S	S	.	.	H	α-helix	trans	-60.6	-45	174.3	-174.1	-163.1	0	0	0	112.5	N281 R282 Y283 V287 L288 L289	N281-H285 PolarHBondContact O-N 3.03Å; R282-H285 WeakPolarHBondContact O-CB 3.36Å; R282-H285 PolarHBondContact O-N 3.44Å; Y283-H285 VanDerWaalsContact C-N 3.32Å; Y283-H285 PolarHBondContact O-N 3.2Å; H285-V287 PolarHBondContact O-N 3.02Å; H285-L288 PolarHBondContact O-N 3.33Å; H285-L289 PolarHBondContact O-N 2.94Å
286	L	94.4	Very high	95.3	Very high	106 Å²	106	74.5 Å²	74.5	56%	0.555	36%	0.364	S	S	*	.	H	α-helix	trans	-63.8	-38.8	178.1	-69.6	173.8	0	0	0	112.5	R282 Y283 F284 L289 A290	R282-L286 WeakPolarHBondContact O-CG 3.26Å; R282-L286 PolarHBondContact O-N 3.4Å; Y283-L286 PolarHBondContact O-N 2.86Å; F284-L286 PolarHBondContact O-N 3.39Å; L286-L289 PolarHBondContact O-N 3.28Å; L286-A290 WeakPolarHBondContact O-CB 3.43Å; L286-A290 PolarHBondContact O-N 3.45Å
287	V	96.9	Very high	95.4	Very high	96 Å²	96	74.2 Å²	74.2	58%	0.582	37%	0.365	S	S	*	.	H	α-helix	trans	-63.5	-44.8	175.4	169.3	0	0	0	0	110.9	Y283 F284 H285 L289 A290 A291	Y283-V287 VanDerWaalsContact O-CG2 3.32Å; Y283-V287 WeakPolarHBondContact O-CG2 3.46Å; Y283-V287 PolarHBondContact O-N 2.87Å; F284-V287 PolarHBondContact O-N 3.5Å; H285-V287 PolarHBondContact O-N 3.02Å; V287-L289 VanDerWaalsContact C-N 3.34Å; V287-L289 PolarHBondContact O-N 2.65Å; V287-A290 PolarHBondContact O-N 3.19Å; V287-A291 WeakPolarHBondContact O-CB 3.42Å; V287-A291 PolarHBondContact O-N 2.79Å
288	L	96.4	Very high	95.5	Very high	10 Å²	10	69.1 Å²	69.1	5%	0.052	35%	0.351	C	S	.	.	H	α-helix	trans	-60.8	-43.2	175.5	-72.9	176.5	0	0	0	112	W271 F284 H285 A291 H292 F350 R352	W271-L288 HydrophobicContact CH2-CD2 4.04Å; W271-L288 HydrophobicContact CZ2-CD2 3.51Å; F284-L288 HydrophobicContact CD1-CD1 4.04Å; F284-L288 HydrophobicContact CE1-CD1 3.54Å; F284-L288 HydrophobicContact CE1-CG 4.31Å; F284-L288 HydrophobicContact CE2-CD1 4.35Å; F284-L288 HydrophobicContact CE2-CD2 4.42Å; F284-L288 HydrophobicContact CE2-CG 4.27Å; F284-L288 HydrophobicContact CZ-CD1 3.71Å; F284-L288 HydrophobicContact CZ-CD2 4.25Å; F284-L288 HydrophobicContact CZ-CG 4.09Å; F284-L288 WeakPolarHBondContact O-CG 3.48Å; F284-L288 PolarHBondContact O-N 2.77Å; H285-L288 PolarHBondContact O-N 3.33Å; L288-A291 PolarHBondContact O-N 2.69Å; L288-H292 WeakPolarHBondContact O-CB 3.4Å; L288-H292 PolarHBondContact O-N 3.41Å; L288-F350 HydrophobicContact CD2-CD1 4.46Å; L288-R352 HydrophobicContact CD1-CB 3.77Å; L288-R352 HydrophobicContact CD1-CG 4.05Å
289	L	95.6	Very high	95.5	Very high	81 Å²	81	67.3 Å²	67.3	42%	0.424	34%	0.341	S	S	.	.	H	α-helix	trans	-63.7	-44.9	176.6	-179.5	61.7	0	0	0	111.7	H285 L286 V287 A291 H292 L293	H285-L289 PolarHBondContact O-N 2.94Å; L286-L289 PolarHBondContact O-N 3.28Å; V287-L289 VanDerWaalsContact C-N 3.34Å; V287-L289 PolarHBondContact O-N 2.65Å; L289-A291 PolarHBondContact O-N 2.87Å; L289-H292 WeakPolarHBondContact O-CB 3.15Å; L289-H292 PolarHBondContact O-N 3.27Å; L289-L293 HydrophobicContact CD1-CD1 4.37Å; L289-L293 HydrophobicContact CD1-CG 4.34Å; L289-L293 HydrophobicContact CG-CD1 4.33Å; L289-L293 WeakPolarHBondContact O-CG 3.36Å; L289-L293 PolarHBondContact O-N 3.02Å
290	A	97.8	Very high	95.5	Very high	60 Å²	60	68 Å²	68	50%	0.496	35%	0.346	S	S	.	.	H	α-helix	trans	-61.9	-43.5	176.5	0	0	0	0	0	111.5	L286 V287 H292 L293 L294	L286-A290 WeakPolarHBondContact O-CB 3.43Å; L286-A290 PolarHBondContact O-N 3.45Å; V287-A290 PolarHBondContact O-N 3.19Å; A290-H292 PolarHBondContact O-N 3.36Å; A290-L293 PolarHBondContact O-N 2.91Å; A290-L294 VanDerWaalsContact O-CB 3.25Å; A290-L294 WeakPolarHBondContact O-CB 3.32Å; A290-L294 PolarHBondContact O-N 3.43Å
291	A	98.1	Very high	95.4	Very high	30 Å²	30	67.9 Å²	67.9	25%	0.248	35%	0.346	C	S	.	.	H	α-helix	trans	-64.4	-38.9	176.7	0	0	0	0	0	112.3	V287 L288 L289 T295 F350	V287-A291 WeakPolarHBondContact O-CB 3.42Å; V287-A291 PolarHBondContact O-N 2.79Å; L288-A291 PolarHBondContact O-N 2.69Å; L289-A291 PolarHBondContact O-N 2.87Å; A291-T295 WeakPolarHBondContact O-CB 3.22Å; A291-T295 PolarHBondContact O-N 2.97Å; A291-T295 PolarHBondContact O-OG1 2.86Å; A291-F350 HydrophobicContact CB-CD1 3.75Å; A291-F350 HydrophobicContact CB-CE1 3.54Å; A291-F350 HydrophobicContact CB-CZ 4.24Å
292	H	97.9	Very high	95.1	Very high	27 Å²	27	74.1 Å²	74.1	13%	0.125	37%	0.366	C	S	.	.	H	α-helix	trans	-59	-54.7	173.4	175.1	64.9	0	0	0	111.8	L288 L289 A290 L294 T295 L296 G347 F350	L288-H292 WeakPolarHBondContact O-CB 3.4Å; L288-H292 PolarHBondContact O-N 3.41Å; L289-H292 WeakPolarHBondContact O-CB 3.15Å; L289-H292 PolarHBondContact O-N 3.27Å; A290-H292 PolarHBondContact O-N 3.36Å; H292-L294 PolarHBondContact O-N 2.94Å; H292-T295 PolarHBondContact O-N 3.44Å; H292-L296 VanDerWaalsContact NE2-CD1 3.3Å; H292-L296 WeakPolarHBondContact NE2-CD1 3.34Å; H292-L296 WeakPolarHBondContact O-CG 3.47Å; H292-L296 PolarHBondContact O-N 2.88Å; H292-G347 VanDerWaalsContact CE1-CA 3.41Å; H292-G347 WeakPolarHBondContact CE1-CA 3.42Å; H292-G347 PolarHBondContact CE1-N 3.43Å; H292-F350 HydrophobicContact CB-CB 3.72Å; H292-F350 HydrophobicContact CB-CD2 4.08Å; H292-F350 HydrophobicContact CB-CG 4.03Å
293	L	97.9	Very high	94.9	Very high	100 Å²	100	68 Å²	68	52%	0.524	34%	0.342	S	S	.	.	H	α-helix	trans	-63.7	-41.6	-178.8	-66.1	177.4	0	0	0	111.9	L289 A290 L296 L297	L289-L293 HydrophobicContact CD1-CD1 4.37Å; L289-L293 HydrophobicContact CD1-CG 4.34Å; L289-L293 HydrophobicContact CG-CD1 4.33Å; L289-L293 WeakPolarHBondContact O-CG 3.36Å; L289-L293 PolarHBondContact O-N 3.02Å; A290-L293 PolarHBondContact O-N 2.91Å; L293-L296 PolarHBondContact O-N 3.19Å; L293-L297 WeakPolarHBondContact O-CB 3.25Å; L293-L297 PolarHBondContact O-N 2.66Å
294	L	98.1	Very high	94.6	Very high	97 Å²	97	60 Å²	60	51%	0.508	31%	0.311	S	S	.	.	H	α-helix	trans	-62	-44.7	175.9	178.8	61.8	0	0	0	111.3	A290 H292 L297 L298	A290-L294 VanDerWaalsContact O-CB 3.25Å; A290-L294 WeakPolarHBondContact O-CB 3.32Å; A290-L294 PolarHBondContact O-N 3.43Å; H292-L294 PolarHBondContact O-N 2.94Å; L294-L297 PolarHBondContact O-N 2.74Å; L294-L298 HydrophobicContact CD1-CD1 4.32Å; L294-L298 HydrophobicContact CD1-CG 4.25Å; L294-L298 HydrophobicContact CG-CD1 4.09Å; L294-L298 HydrophobicContact CG-CG 4.45Å; L294-L298 WeakPolarHBondContact O-CB 3.46Å; L294-L298 VanDerWaalsContact O-CG 3.26Å; L294-L298 WeakPolarHBondContact O-CG 3.39Å; L294-L298 PolarHBondContact O-N 2.87Å
295	T	98.1	Very high	94.1	Very high	27 Å²	27	60.5 Å²	60.5	17%	0.166	31%	0.313	C	S	.	.	H	α-helix	trans	-64.4	-43.8	179.4	-56.2	0	0	0	0	111.1	A291 H292 L297 L298 F299 I346 F350	A291-T295 WeakPolarHBondContact O-CB 3.22Å; A291-T295 PolarHBondContact O-N 2.97Å; A291-T295 PolarHBondContact O-OG1 2.86Å; H292-T295 PolarHBondContact O-N 3.44Å; T295-L297 VanDerWaalsContact C-N 3.35Å; T295-L297 PolarHBondContact O-N 3.19Å; T295-L298 PolarHBondContact O-N 3.43Å; T295-F299 HydrophobicContact CG2-CD2 3.84Å; T295-F299 HydrophobicContact CG2-CE2 3.91Å; T295-F299 WeakPolarHBondContact O-CD2 3.15Å; T295-F299 PolarHBondContact O-N 3.27Å; T295-I346 HydrophobicContact CG2-CD1 4.05Å; T295-I346 HydrophobicContact CG2-CG1 4.06Å; T295-I346 HydrophobicContact CG2-CG2 3.89Å; T295-F350 HydrophobicContact CG2-CE2 4.07Å; T295-F350 WeakPolarHBondContact OG1-CE2 3.47Å; T295-F350 WeakPolarHBondContact OG1-CZ 3.44Å
296	L	97.9	Very high	93.2	Very high	12 Å²	12	58.3 Å²	58.3	6%	0.063	30%	0.301	C	S	.	.	H	α-helix	trans	-57.6	-46.7	173.4	-75.7	173.2	0	0	0	111.9	P211 H292 L293 L298 F299 A300 W304 I346	P211-L296 HydrophobicContact CB-CD1 4.02Å; P211-L296 HydrophobicContact CB-CD2 4.2Å; P211-L296 HydrophobicContact CG-CD1 3.74Å; H292-L296 VanDerWaalsContact NE2-CD1 3.3Å; H292-L296 WeakPolarHBondContact NE2-CD1 3.34Å; H292-L296 WeakPolarHBondContact O-CG 3.47Å; H292-L296 PolarHBondContact O-N 2.88Å; L293-L296 PolarHBondContact O-N 3.19Å; L296-L298 PolarHBondContact O-N 3.42Å; L296-F299 PolarHBondContact O-N 2.84Å; L296-A300 WeakPolarHBondContact O-CB 3.34Å; L296-A300 PolarHBondContact O-N 3.13Å; L296-W304 HydrophobicContact CD2-CH2 4.06Å; L296-I346 HydrophobicContact CD2-CB 4.15Å; L296-I346 HydrophobicContact CD2-CD1 3.9Å; L296-I346 HydrophobicContact CD2-CG2 4.1Å; L296-I346 HydrophobicContact CG-CG2 3.95Å
297	L	95.8	Very high	92	Very high	92 Å²	92	56 Å²	56	48%	0.482	29%	0.293	S	S	.	.	H	α-helix	trans	-60.8	-45	178.2	179.6	62.4	0	0	0	111.5	L293 L294 T295 F299 A300 L301	L293-L297 WeakPolarHBondContact O-CB 3.25Å; L293-L297 PolarHBondContact O-N 2.66Å; L294-L297 PolarHBondContact O-N 2.74Å; T295-L297 VanDerWaalsContact C-N 3.35Å; T295-L297 PolarHBondContact O-N 3.19Å; L297-F299 PolarHBondContact O-N 3.4Å; L297-A300 PolarHBondContact O-N 3.19Å; L297-L301 HydrophobicContact CD1-CD1 3.76Å; L297-L301 HydrophobicContact CD1-CG 4.02Å; L297-L301 HydrophobicContact CG-CD1 3.79Å; L297-L301 HydrophobicContact CG-CG 4.41Å; L297-L301 WeakPolarHBondContact O-CB 3.18Å; L297-L301 VanDerWaalsContact O-CG 3.24Å; L297-L301 WeakPolarHBondContact O-CG 3.35Å; L297-L301 PolarHBondContact O-N 2.83Å
298	L	95.1	Very high	90.6	Very high	68 Å²	68	55.2 Å²	55.2	36%	0.356	30%	0.304	S	S	.	.	H	α-helix	trans	-61.5	-44.2	177.1	-72.7	174.3	0	0	0	111.7	L294 T295 L296 L301 R302 W419	L294-L298 HydrophobicContact CD1-CD1 4.32Å; L294-L298 HydrophobicContact CD1-CG 4.25Å; L294-L298 HydrophobicContact CG-CD1 4.09Å; L294-L298 HydrophobicContact CG-CG 4.45Å; L294-L298 WeakPolarHBondContact O-CB 3.46Å; L294-L298 VanDerWaalsContact O-CG 3.26Å; L294-L298 WeakPolarHBondContact O-CG 3.39Å; L294-L298 PolarHBondContact O-N 2.87Å; T295-L298 PolarHBondContact O-N 3.43Å; L296-L298 PolarHBondContact O-N 3.42Å; L298-L301 PolarHBondContact O-N 3.07Å; L298-R302 VanDerWaalsContact O-CB 3.27Å; L298-R302 WeakPolarHBondContact O-CB 3.29Å; L298-R302 PolarHBondContact O-N 3.31Å; L298-W419 HydrophobicContact CB-CH2 3.89Å; L298-W419 HydrophobicContact CB-CZ3 3.89Å
299	F	94.6	Very high	89.6	Confident	9 Å²	9	55.5 Å²	55.5	4%	0.039	31%	0.305	C	S	.	.	H	α-helix	trans	-63.6	-44.4	175.6	-93.1	-96.6	0	0	0	111.9	T295 L296 L297 L301 R303 W304 T342 I346 L418 W419	T295-F299 HydrophobicContact CG2-CD2 3.84Å; T295-F299 HydrophobicContact CG2-CE2 3.91Å; T295-F299 WeakPolarHBondContact O-CD2 3.15Å; T295-F299 PolarHBondContact O-N 3.27Å; L296-F299 PolarHBondContact O-N 2.84Å; L297-F299 PolarHBondContact O-N 3.4Å; F299-L301 PolarHBondContact O-N 3.19Å; F299-R303 HydrophobicContact CD1-CB 3.91Å; F299-R303 HydrophobicContact CD1-CG 4.13Å; F299-R303 HydrophobicContact CE1-CB 4.49Å; F299-R303 HydrophobicContact CE1-CG 4.37Å; F299-R303 CarbonylContact O-C 3.56Å; F299-R303 WeakPolarHBondContact O-CA 3.29Å; F299-R303 WeakPolarHBondContact O-CB 3.4Å; F299-R303 PolarHBondContact O-N 3.4Å; F299-W304 HydrophobicContact CB-CD2 4.43Å; F299-W304 HydrophobicContact CB-CZ2 4.25Å; F299-W304 AromaticContact CD1-NE1 3.92Å; F299-W304 PolarHBondContact O-N 2.81Å; F299-T342 HydrophobicContact CD1-CG2 3.65Å; F299-T342 HydrophobicContact CE1-CG2 3.62Å; F299-T342 HydrophobicContact CG-CG2 4.35Å; F299-T342 HydrophobicContact CZ-CG2 4.29Å; F299-I346 HydrophobicContact CB-CD1 4.22Å; F299-I346 HydrophobicContact CD1-CD1 4.47Å; F299-I346 HydrophobicContact CD2-CD1 3.68Å; F299-I346 HydrophobicContact CE2-CD1 4.11Å; F299-I346 HydrophobicContact CG-CD1 3.87Å; F299-L418 HydrophobicContact CE1-CB 4.08Å; F299-L418 HydrophobicContact CZ-CB 4.2Å; F299-W419 AromaticContact CD2-CE3 3.9Å; F299-W419 HydrophobicContact CD2-CE3 3.9Å; F299-W419 HydrophobicContact CD2-CZ3 4.07Å; F299-W419 HydrophobicContact CE1-CE3 4.44Å; F299-W419 AromaticContact CE2-CE3 3.69Å; F299-W419 HydrophobicContact CE2-CE3 3.69Å; F299-W419 HydrophobicContact CE2-CZ3 4.31Å; F299-W419 HydrophobicContact CG-CE3 4.4Å; F299-W419 HydrophobicContact CG-CZ3 4.46Å; F299-W419 HydrophobicContact CZ-CB 4.17Å; F299-W419 AromaticContact CZ-CE3 3.99Å; F299-W419 HydrophobicContact CZ-CE3 3.99Å
300	A	92.8	Very high	88.9	Confident	13 Å²	13	56.1 Å²	56.1	11%	0.107	31%	0.309	C	S	.	.	I	π-helix	trans	-59.7	-44.9	176.7	0	0	0	0	0	112	F215 L296 L297 W304 K305	F215-A300 HydrophobicContact CD2-CB 4.12Å; F215-A300 HydrophobicContact CE2-CB 4.31Å; L296-A300 WeakPolarHBondContact O-CB 3.34Å; L296-A300 PolarHBondContact O-N 3.13Å; L297-A300 PolarHBondContact O-N 3.19Å; A300-W304 HydrophobicContact CB-CE3 3.89Å; A300-W304 HydrophobicContact CB-CZ3 4.29Å; A300-K305 WeakPolarHBondContact O-CB 3.4Å; A300-K305 PolarHBondContact O-N 3.16Å
301	L	89.9	Confident	88.2	Confident	60 Å²	60	56.1 Å²	56.1	31%	0.314	30%	0.3	S	S	.	.	I	π-helix	trans	-75.6	-35	-176.7	-68.8	172.7	0	0	0	113.9	L297 L298 F299 K305 I311	L297-L301 HydrophobicContact CD1-CD1 3.76Å; L297-L301 HydrophobicContact CD1-CG 4.02Å; L297-L301 HydrophobicContact CG-CD1 3.79Å; L297-L301 HydrophobicContact CG-CG 4.41Å; L297-L301 WeakPolarHBondContact O-CB 3.18Å; L297-L301 VanDerWaalsContact O-CG 3.24Å; L297-L301 WeakPolarHBondContact O-CG 3.35Å; L297-L301 PolarHBondContact O-N 2.83Å; L298-L301 PolarHBondContact O-N 3.07Å; F299-L301 PolarHBondContact O-N 3.19Å; L301-K305 VanDerWaalsContact O-CE 3.23Å; L301-K305 WeakPolarHBondContact O-CE 3.41Å; L301-I311 HydrophobicContact CD2-CB 3.97Å; L301-I311 HydrophobicContact CD2-CD1 3.54Å; L301-I311 HydrophobicContact CD2-CG1 4.34Å; L301-I311 HydrophobicContact CD2-CG2 3.99Å; L301-I311 HydrophobicContact CG-CD1 4.34Å
302	R	87.6	Confident	87.6	Confident	182 Å²	182	58.6 Å²	58.6	69%	0.687	31%	0.312	S	S	*	.	I	π-helix	trans	-111.2	-25.7	-169	-60.1	-65.8	-170.2	154.2	0.7	114.6	L298 W419	L298-R302 VanDerWaalsContact O-CB 3.27Å; L298-R302 WeakPolarHBondContact O-CB 3.29Å; L298-R302 PolarHBondContact O-N 3.31Å; R302-W419 HydrophobicContact CB-CH2 3.8Å; R302-W419 HydrophobicContact CB-CZ3 4.27Å; R302-W419 HydrophobicContact CG-CH2 3.97Å
303	R	87.2	Confident	87	Confident	72 Å²	72	58.5 Å²	58.5	27%	0.272	31%	0.311	S	S	.	.	I	π-helix	trans	-119.7	-41	-170.5	-64.6	-65.2	167.6	-170.1	-4.8	114.5	F299 W419 A421	F299-R303 HydrophobicContact CD1-CB 3.91Å; F299-R303 HydrophobicContact CD1-CG 4.13Å; F299-R303 HydrophobicContact CE1-CB 4.49Å; F299-R303 HydrophobicContact CE1-CG 4.37Å; F299-R303 CarbonylContact O-C 3.56Å; F299-R303 WeakPolarHBondContact O-CA 3.29Å; F299-R303 WeakPolarHBondContact O-CB 3.4Å; F299-R303 PolarHBondContact O-N 3.4Å; R303-W419 HydrophobicContact CG-CE3 3.83Å; R303-W419 HydrophobicContact CG-CZ3 3.99Å; R303-W419 PolarHBondContact NE-O 3Å; R303-W419 PolarHBondContact NH1-O 3.41Å; R303-W419 PolarHBondContact NH2-O 3.4Å; R303-A421 PolarHBondContact NH1-O 3.37Å
304	W	89.6	Confident	86.4	Confident	12 Å²	12	53.9 Å²	53.9	5%	0.045	29%	0.287	C	S	.	.	I	π-helix	trans	-81.4	-34.5	-179.4	-59.7	-17.2	0	0	0	112.4	F215 L296 F299 A300 Q335 I339 T342	F215-W304 HydrophobicContact CB-CE3 3.97Å; F215-W304 HydrophobicContact CB-CZ3 4.2Å; F215-W304 HydrophobicContact CD1-CB 4.06Å; F215-W304 HydrophobicContact CD1-CE3 4.32Å; F215-W304 HydrophobicContact CD2-CB 4.34Å; F215-W304 AromaticContact CD2-CE3 3.87Å; F215-W304 HydrophobicContact CD2-CE3 3.87Å; F215-W304 HydrophobicContact CE1-CB 3.61Å; F215-W304 HydrophobicContact CE2-CB 3.9Å; F215-W304 HydrophobicContact CE2-CE3 4.49Å; F215-W304 HydrophobicContact CG-CB 4.41Å; F215-W304 AromaticContact CG-CE3 3.77Å; F215-W304 HydrophobicContact CG-CE3 3.77Å; F215-W304 HydrophobicContact CG-CZ3 4.48Å; F215-W304 VanDerWaalsContact CZ-C 3.47Å; F215-W304 HydrophobicContact CZ-CB 3.52Å; L296-W304 HydrophobicContact CD2-CH2 4.06Å; F299-W304 HydrophobicContact CB-CD2 4.43Å; F299-W304 HydrophobicContact CB-CZ2 4.25Å; F299-W304 AromaticContact CD1-NE1 3.92Å; F299-W304 PolarHBondContact O-N 2.81Å; A300-W304 HydrophobicContact CB-CE3 3.89Å; A300-W304 HydrophobicContact CB-CZ3 4.29Å; W304-Q335 PolarHBondContact O-NE2 3.07Å; W304-Q335 VanDerWaalsContact O-NE2 3.15Å; W304-I339 HydrophobicContact CB-CD1 4.2Å; W304-I339 HydrophobicContact CB-CG1 4.04Å; W304-I339 HydrophobicContact CD2-CB 4.44Å; W304-I339 HydrophobicContact CD2-CG1 4.11Å; W304-I339 HydrophobicContact CD2-CG2 3.91Å; W304-I339 HydrophobicContact CE3-CG2 3.95Å; W304-I339 HydrophobicContact CG-CD1 4.42Å; W304-I339 HydrophobicContact CG-CG1 3.73Å; W304-I339 HydrophobicContact CG-CG2 4.41Å; W304-I339 HydrophobicContact CH2-CG2 4.37Å; W304-I339 HydrophobicContact CZ2-CG2 4.31Å; W304-I339 HydrophobicContact CZ3-CG2 4.19Å; W304-T342 HydrophobicContact CZ2-CG2 4.26Å
305	K	82.8	Confident	86	Confident	39 Å²	39	53 Å²	53	17%	0.17	28%	0.283	C	S	.	.	S	Bend	trans	-67.8	143.2	175.8	-172	-172.3	71.6	62.4	0	111.7	F215 A300 L301 E309	F215-K305 HydrophobicContact CZ-CB 4.42Å; A300-K305 WeakPolarHBondContact O-CB 3.4Å; A300-K305 PolarHBondContact O-N 3.16Å; L301-K305 VanDerWaalsContact O-CE 3.23Å; L301-K305 WeakPolarHBondContact O-CE 3.41Å; K305-E309 HydrophobicContact CD-CB 4.38Å; K305-E309 WeakPolarHBondContact CD-O 3.33Å; K305-E309 WeakPolarHBondContact CE-O 3.44Å; K305-E309 HydrophobicContact CG-CB 4.14Å; K305-E309 PolarHBondContact NZ-O 3.17Å
306	R	73.6	Confident	85.5	Confident	31 Å²	31	55.9 Å²	55.9	12%	0.117	29%	0.293	C	S	.	.	P	Polyproline II helix	trans	-63.7	145.2	171.4	-66.6	176.9	171.6	-176	-5	111.3	G308 E309	R306-G308 PolarHBondContact O-N 3.22Å; R306-E309 HydrophobicContact CB-CG 4.12Å; R306-E309 PolarHBondContact O-N 2.78Å
307	P	69.2	Low	84.8	Confident	59 Å²	59	58 Å²	58	38%	0.383	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.8	136	171	-24.8	34.4	0	0	0	110.9	E309 P423 T425	P307-E309 VanDerWaalsContact C-N 3.33Å; P307-E309 PolarHBondContact O-N 2.97Å; P307-P423 HydrophobicContact CG-CB 3.97Å; P307-P423 HydrophobicContact CG-CG 4.2Å; P307-T425 WeakPolarHBondContact CD-OG1 3.43Å
308	G	67	Low	84.2	Confident	79 Å²	79	55.1 Å²	55.1	81%	0.814	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	82.4	-16.8	178	0	0	0	0	0	117.4	R306	R306-G308 PolarHBondContact O-N 3.22Å
309	E	74.5	Confident	83.5	Confident	15 Å²	15	56.8 Å²	56.8	7%	0.07	31%	0.307	C	S	.	.			trans	-77.5	153.9	175.6	-67.7	-177.4	168.3	0	0	111.8	K305 R306 P307 I323	K305-E309 HydrophobicContact CD-CB 4.38Å; K305-E309 WeakPolarHBondContact CD-O 3.33Å; K305-E309 WeakPolarHBondContact CE-O 3.44Å; K305-E309 HydrophobicContact CG-CB 4.14Å; K305-E309 PolarHBondContact NZ-O 3.17Å; R306-E309 HydrophobicContact CB-CG 4.12Å; R306-E309 PolarHBondContact O-N 2.78Å; P307-E309 VanDerWaalsContact C-N 3.33Å; P307-E309 PolarHBondContact O-N 2.97Å; E309-I323 HydrophobicContact CG-CD1 3.85Å
310	N	81.5	Confident	82.8	Confident	95 Å²	95	63.1 Å²	63.1	51%	0.508	33%	0.334	S	S	.	.			trans	-94.9	148.2	165.3	-169.2	-26.3	0	0	0	108.3	V312 E313	N310-V312 PolarHBondContact O-N 3.07Å; N310-V312 PolarHBondContact OD1-N 3.06Å; N310-E313 HydrophobicContact CB-CG 4.14Å; N310-E313 VanDerWaalsContact O-CB 3.25Å; N310-E313 WeakPolarHBondContact O-CB 3.24Å; N310-E313 PolarHBondContact O-N 2.88Å
311	I	83.8	Confident	82.2	Confident	60 Å²	60	63.4 Å²	63.4	31%	0.308	33%	0.333	S	S	.	.	G	3₁₀ helix	trans	-58.9	-29.1	176.2	-159.3	163.8	0	0	0	111.8	L301 E313 L314	L301-I311 HydrophobicContact CD2-CB 3.97Å; L301-I311 HydrophobicContact CD2-CD1 3.54Å; L301-I311 HydrophobicContact CD2-CG1 4.34Å; L301-I311 HydrophobicContact CD2-CG2 3.99Å; L301-I311 HydrophobicContact CG-CD1 4.34Å; I311-E313 PolarHBondContact O-N 3.22Å; I311-L314 HydrophobicContact CG1-CD1 3.91Å; I311-L314 VanDerWaalsContact O-CB 3.25Å; I311-L314 WeakPolarHBondContact O-CB 3.36Å; I311-L314 PolarHBondContact O-N 3.42Å; I311-L314 VanDerWaalsContact O-N 3.07Å
312	V	85.7	Confident	81.1	Confident	81 Å²	81	69.1 Å²	69.1	49%	0.491	36%	0.355	S	S	.	.	G	3₁₀ helix	trans	-64.9	-27.4	174.5	-176	0	0	0	0	112	N310 L314 L315	N310-V312 PolarHBondContact O-N 3.07Å; N310-V312 PolarHBondContact OD1-N 3.06Å; V312-L314 PolarHBondContact O-N 3.03Å; V312-L315 HydrophobicContact CG1-CD1 4.48Å; V312-L315 WeakPolarHBondContact O-CB 3.48Å; V312-L315 PolarHBondContact O-N 2.86Å; V312-L315 VanDerWaalsContact O-N 3.11Å
313	E	84.9	Confident	80.1	Confident	25 Å²	25	64 Å²	64	12%	0.117	34%	0.34	C	S	.	.	G	3₁₀ helix	trans	-66.8	-24.1	174.5	-63.2	-70.8	149.4	0	0	111.9	N310 I311 L315 K316 R321	N310-E313 HydrophobicContact CB-CG 4.14Å; N310-E313 VanDerWaalsContact O-CB 3.25Å; N310-E313 WeakPolarHBondContact O-CB 3.24Å; N310-E313 PolarHBondContact O-N 2.88Å; I311-E313 PolarHBondContact O-N 3.22Å; E313-L315 PolarHBondContact O-N 3.37Å; E313-K316 PolarHBondContact O-N 3.38Å; E313-K316 IonicContact OE1-NZ 3.68Å; E313-K316 PolarHBondContact OE1-NZ 3.34Å; E313-K316 WeakPolarHBondContact OE2-CD 3.01Å; E313-K316 IonicContact OE2-NZ 2.74Å; E313-K316 PolarHBondContact OE2-NZ 2.73Å; E313-K316 VanDerWaalsContact OE2-NZ 3.1Å; E313-R321 PolarHBondContact O-NE 3.47Å
314	L	85.1	Confident	78.7	Confident	3 Å²	3	64.6 Å²	64.6	2%	0.016	35%	0.354	C	S	.	.	G	3₁₀ helix	trans	-66	-24.5	173.5	-58.9	177	0	0	0	112	F215 L218 W219 G222 I311 V312 K316 R321	F215-L314 HydrophobicContact CD2-CD1 4.13Å; F215-L314 HydrophobicContact CE2-CD1 3.51Å; F215-L314 HydrophobicContact CZ-CD1 3.8Å; L218-L314 HydrophobicContact CB-CB 4.36Å; L218-L314 VanDerWaalsContact O-O 3.12Å; W219-L314 HydrophobicContact CB-CD2 4.27Å; W219-L314 HydrophobicContact CG-CD2 4.48Å; G222-L314 WeakPolarHBondContact CA-O 3.32Å; I311-L314 HydrophobicContact CG1-CD1 3.91Å; I311-L314 VanDerWaalsContact O-CB 3.25Å; I311-L314 WeakPolarHBondContact O-CB 3.36Å; I311-L314 PolarHBondContact O-N 3.42Å; I311-L314 VanDerWaalsContact O-N 3.07Å; V312-L314 PolarHBondContact O-N 3.03Å; L314-K316 VanDerWaalsContact C-N 3.31Å; L314-R321 PolarHBondContact O-NH2 3.26Å
315	L	88.6	Confident	77.1	Confident	80 Å²	80	66.7 Å²	66.7	42%	0.419	37%	0.374	S	S	.	.	G	3₁₀ helix	trans	-74.2	-26.1	177.3	-56.8	179.7	0	0	0	112	L218 L223 V312 E313	L218-L315 HydrophobicContact CD1-CD2 4.46Å; L218-L315 HydrophobicContact CD2-CD2 4.24Å; L223-L315 HydrophobicContact CB-CB 4.4Å; L223-L315 HydrophobicContact CB-CD2 4.41Å; L223-L315 WeakPolarHBondContact CB-O 3.46Å; L223-L315 HydrophobicContact CD1-CD2 4.49Å; L223-L315 PolarHBondContact N-O 3.15Å; V312-L315 HydrophobicContact CG1-CD1 4.48Å; V312-L315 WeakPolarHBondContact O-CB 3.48Å; V312-L315 PolarHBondContact O-N 2.86Å; V312-L315 VanDerWaalsContact O-N 3.11Å; E313-L315 PolarHBondContact O-N 3.37Å
316	K	87.4	Confident	75.5	Confident	87 Å²	87	72 Å²	72	38%	0.378	40%	0.399	S	S	.	.	S	Bend	trans	-75	152.7	178.5	-61.6	-179.6	-172.2	167.9	0	111.1	E313 L314 R321	E313-K316 PolarHBondContact O-N 3.38Å; E313-K316 IonicContact OE1-NZ 3.68Å; E313-K316 PolarHBondContact OE1-NZ 3.34Å; E313-K316 WeakPolarHBondContact OE2-CD 3.01Å; E313-K316 IonicContact OE2-NZ 2.74Å; E313-K316 PolarHBondContact OE2-NZ 2.73Å; E313-K316 VanDerWaalsContact OE2-NZ 3.1Å; L314-K316 VanDerWaalsContact C-N 3.31Å; K316-R321 PolarHBondContact O-NE 2.94Å; K316-R321 PolarHBondContact O-NH2 3.28Å
317	E	83.6	Confident	74.3	Confident	55 Å²	55	73.7 Å²	73.7	26%	0.257	43%	0.427	S	S	.	.			trans	-58	140.1	172.2	-66.3	-177.5	145.2	0	0	110.5	S319 K320	E317-S319 PolarHBondContact O-N 3.42Å; E317-S319 VanDerWaalsContact O-N 3.11Å; E317-K320 HydrophobicContact CB-CD 4.31Å; E317-K320 HydrophobicContact CB-CG 4.47Å; E317-K320 PolarHBondContact O-N 2.91Å; E317-K320 VanDerWaalsContact OE2-CE 3.27Å; E317-K320 WeakPolarHBondContact OE2-CE 3.44Å; E317-K320 IonicContact OE2-NZ 3.1Å; E317-K320 PolarHBondContact OE2-NZ 3.47Å
318	P	83.4	Confident	73.4	Confident	33 Å²	33	78.2 Å²	78.2	21%	0.214	45%	0.446	C	S	.	.	G	3₁₀ helix	trans	-53.2	-35.2	-178.1	-27.5	33.1	0	0	0	114.2	E220 K320 R321	E220-P318 WeakPolarHBondContact O-CG 3.44Å; P318-K320 PolarHBondContact O-N 3.39Å; P318-R321 PolarHBondContact O-N 3.27Å
319	S	80.6	Confident	72.8	Confident	103 Å²	103	76.6 Å²	76.6	72%	0.72	42%	0.42	S	S	*	.	G	3₁₀ helix	trans	-68	-20.2	178.2	52.9	0	0	0	0	114.2	E317	E317-S319 PolarHBondContact O-N 3.42Å; E317-S319 VanDerWaalsContact O-N 3.11Å
320	K	80.2	Confident	71.9	Confident	141 Å²	141	82.6 Å²	82.6	61%	0.613	46%	0.458	S	S	*	.	G	3₁₀ helix	trans	-101.9	3.1	-177.4	-65.7	175.1	177	152.9	0	112.8	E317 P318	E317-K320 HydrophobicContact CB-CD 4.31Å; E317-K320 HydrophobicContact CB-CG 4.47Å; E317-K320 PolarHBondContact O-N 2.91Å; E317-K320 VanDerWaalsContact OE2-CE 3.27Å; E317-K320 WeakPolarHBondContact OE2-CE 3.44Å; E317-K320 IonicContact OE2-NZ 3.1Å; E317-K320 PolarHBondContact OE2-NZ 3.47Å; P318-K320 PolarHBondContact O-N 3.39Å
321	R	81.1	Confident	71.4	Confident	19 Å²	19	80.1 Å²	80.1	7%	0.072	45%	0.445	C	S	.	.	S	Bend	trans	-78.7	141.5	-178.9	-66.3	-178.4	-173	161.8	3.5	110.6	L218 W219 E313 L314 K316 P318 I323	L218-R321 PolarHBondContact O-NH2 2.69Å; W219-R321 PolarHBondContact O-NH1 2.8Å; W219-R321 PolarHBondContact O-NH2 3.44Å; E313-R321 PolarHBondContact O-NE 3.47Å; L314-R321 PolarHBondContact O-NH2 3.26Å; K316-R321 PolarHBondContact O-NE 2.94Å; K316-R321 PolarHBondContact O-NH2 3.28Å; P318-R321 PolarHBondContact O-N 3.27Å; R321-I323 PolarHBondContact O-N 3.41Å
322	K	66.9	Low	71.2	Confident	180 Å²	180	78.7 Å²	78.7	78%	0.783	44%	0.436	S	S	*	.	S	Bend	trans	-57.3	-34.8	179.1	-68.5	-176.7	177.9	-177.5	0	112.8
323	I	65	Low	71.2	Confident	74 Å²	74	77.3 Å²	77.3	38%	0.379	43%	0.425	S	S	.	.	S	Bend	trans	-102.7	112.3	173	-55.7	179.4	0	0	0	105.5	E309 R321 A325	E309-I323 HydrophobicContact CG-CD1 3.85Å; R321-I323 PolarHBondContact O-N 3.41Å; I323-A325 PolarHBondContact O-N 3.47Å
324	P	59.1	Low	71.4	Confident	86 Å²	86	76.4 Å²	76.4	56%	0.558	42%	0.421	S	S	*	.			trans	-55	138.4	175.7	-21.3	30.5	0	0	0	109.4	Q326	P324-Q326 PolarHBondContact O-N 3.32Å
325	A	56.3	Low	71.7	Confident	56 Å²	56	77 Å²	77	46%	0.463	42%	0.424	S	S	.	.			trans	-65.3	83	163.5	0	0	0	0	0	107.5	I323 G327	I323-A325 PolarHBondContact O-N 3.47Å; A325-G327 PolarHBondContact O-N 3.29Å
326	Q	48.9	Very low	71.9	Confident	149 Å²	149	73.2 Å²	73.2	70%	0.696	40%	0.404	S	S	*	.			trans	-52.2	128.8	172.2	-76.5	176.9	-21.6	0	0	107.5	P324 T329	P324-Q326 PolarHBondContact O-N 3.32Å; Q326-T329 HydrophobicContact CB-CG2 4.41Å
327	G	46.7	Very low	72.3	Confident	68 Å²	68	69.1 Å²	69.1	70%	0.701	39%	0.386	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50	148.2	-171.9	0	0	0	0	0	112.4	A325 T329	A325-G327 PolarHBondContact O-N 3.29Å; G327-T329 VanDerWaalsContact C-N 3.28Å; G327-T329 PolarHBondContact O-N 3.16Å
328	I	51	Low	72.9	Confident	153 Å²	153	67.8 Å²	67.8	79%	0.785	38%	0.381	S	S	*	.	T	Hydrogen-bonded Turn	trans	-2.1	78.8	180	-54	170.2	0	0	0	112
329	T	54.7	Low	73.5	Confident	46 Å²	46	66.3 Å²	66.3	28%	0.282	37%	0.371	S	S	.	.			trans	-67.3	149.3	175.9	51.9	0	0	0	0	108.1	Q326 G327 D331 H332	Q326-T329 HydrophobicContact CB-CG2 4.41Å; G327-T329 VanDerWaalsContact C-N 3.28Å; G327-T329 PolarHBondContact O-N 3.16Å; T329-D331 PolarHBondContact O-N 3.13Å; T329-H332 WeakPolarHBondContact O-CB 3.35Å; T329-H332 PolarHBondContact O-N 2.86Å
330	V	56.2	Low	74.3	Confident	141 Å²	141	61.6 Å²	61.6	86%	0.855	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.7	-19.1	179.4	-179.9	0	0	0	0	113.6
331	D	69.6	Low	75.2	Confident	43 Å²	43	55 Å²	55	23%	0.23	31%	0.309	C	S	.	.	T	Hydrogen-bonded Turn	trans	-103.7	6.1	179.4	-68.7	-63	0	0	0	116	K143 T329 Q335	K143-D331 IonicContact NZ-OD1 2.74Å; K143-D331 PolarHBondContact NZ-OD1 3.47Å; T329-D331 PolarHBondContact O-N 3.13Å; D331-Q335 VanDerWaalsContact O-CB 3.32Å; D331-Q335 WeakPolarHBondContact O-CB 3.44Å; D331-Q335 PolarHBondContact O-N 3.37Å; D331-Q335 VanDerWaalsContact O-N 3.09Å
332	H	80.6	Confident	76	Confident	29 Å²	29	54.1 Å²	54.1	13%	0.134	31%	0.306	C	S	.	.	H	α-helix	trans	-66.4	-51.3	-178.2	-172.9	-72.3	0	0	0	112.7	W219 E220 T329 Q335 I336	W219-H332 AromaticContact CH2-CD2 3.77Å; E220-H332 IonicContact OE2-CE1 3.2Å; E220-H332 PolarHBondContact OE2-CE1 3.35Å; E220-H332 IonicContact OE2-NE2 3.23Å; E220-H332 PolarHBondContact OE2-NE2 2.79Å; T329-H332 WeakPolarHBondContact O-CB 3.35Å; T329-H332 PolarHBondContact O-N 2.86Å; H332-Q335 WeakPolarHBondContact O-CB 3.47Å; H332-Q335 PolarHBondContact O-N 3.11Å; H332-Q335 VanDerWaalsContact O-N 3.09Å; H332-I336 PolarHBondContact O-N 2.91Å; H332-I336 VanDerWaalsContact O-N 3.11Å
333	E	86.2	Confident	77.5	Confident	52 Å²	52	45.6 Å²	45.6	24%	0.243	27%	0.269	C	S	.	.	H	α-helix	trans	-59	-49.3	177.6	-73.2	177.9	-172.8	0	0	112.5	R140 L185 Q335 I336 V337	R140-E333 WeakPolarHBondContact CB-OE2 3.34Å; R140-E333 IonicContact CZ-OE1 2.73Å; R140-E333 IonicContact NE-OE1 3.53Å; R140-E333 IonicContact NE-OE2 2.81Å; R140-E333 VanDerWaalsContact NH1-CD 3.29Å; R140-E333 IonicContact NH1-OE1 3.05Å; R140-E333 PolarHBondContact NH1-OE1 3.28Å; R140-E333 IonicContact NH1-OE2 3.55Å; L185-E333 HydrophobicContact CD2-CB 3.84Å; L185-E333 HydrophobicContact CD2-CG 4.08Å; L185-E333 WeakPolarHBondContact CD2-O 3.39Å; E333-Q335 PolarHBondContact O-N 3.47Å; E333-I336 PolarHBondContact O-N 3.03Å; E333-V337 WeakPolarHBondContact O-CG2 3.41Å; E333-V337 PolarHBondContact O-N 3.35Å
334	P	89.1	Confident	79.1	Confident	6 Å²	6	42 Å²	42	4%	0.039	25%	0.25	C	S	.	.	H	α-helix	trans	-57.5	-34.9	173	-26	32.9	0	0	0	114.5	T141 K143 V337 L338 Y368	T141-P334 HydrophobicContact CG2-CG 4.45Å; K143-P334 HydrophobicContact CD-CB 4.49Å; K143-P334 HydrophobicContact CG-CB 4.33Å; P334-V337 PolarHBondContact O-N 3.18Å; P334-L338 VanDerWaalsContact O-CB 3.25Å; P334-L338 WeakPolarHBondContact O-CB 3.49Å; P334-L338 PolarHBondContact O-N 3Å; P334-Y368 WeakPolarHBondContact CA-OH 3.16Å; P334-Y368 WeakPolarHBondContact CB-OH 3.21Å; P334-Y368 PolarHBondContact O-OH 2.97Å
335	Q	90.1	Very high	81	Confident	16 Å²	16	38 Å²	38	8%	0.075	22%	0.224	C	C	.	.	H	α-helix	trans	-66.7	-44.2	179.9	-175.4	169.2	0.4	0	0	111.7	W219 W304 D331 H332 E333 V337 L338 I339 L424	W219-Q335 HydrophobicContact CH2-CB 4.06Å; W219-Q335 HydrophobicContact CH2-CG 3.8Å; W219-Q335 VanDerWaalsContact CZ2-OE1 3.24Å; W219-Q335 HydrophobicContact CZ3-CB 4.2Å; W219-Q335 HydrophobicContact CZ3-CG 3.84Å; W304-Q335 PolarHBondContact O-NE2 3.07Å; W304-Q335 VanDerWaalsContact O-NE2 3.15Å; D331-Q335 VanDerWaalsContact O-CB 3.32Å; D331-Q335 WeakPolarHBondContact O-CB 3.44Å; D331-Q335 PolarHBondContact O-N 3.37Å; D331-Q335 VanDerWaalsContact O-N 3.09Å; H332-Q335 WeakPolarHBondContact O-CB 3.47Å; H332-Q335 PolarHBondContact O-N 3.11Å; H332-Q335 VanDerWaalsContact O-N 3.09Å; E333-Q335 PolarHBondContact O-N 3.47Å; Q335-V337 PolarHBondContact O-N 3.15Å; Q335-L338 PolarHBondContact O-N 3.42Å; Q335-I339 HydrophobicContact CG-CD1 3.71Å; Q335-I339 HydrophobicContact CG-CG1 4.45Å; Q335-I339 WeakPolarHBondContact O-CB 3.18Å; Q335-I339 WeakPolarHBondContact O-CD1 3.24Å; Q335-I339 WeakPolarHBondContact O-CG1 3.38Å; Q335-I339 PolarHBondContact O-N 2.88Å; Q335-L424 HydrophobicContact CB-CD1 4.1Å; Q335-L424 HydrophobicContact CG-CD1 4.48Å
336	I	93.9	Very high	83	Confident	1 Å²	1	35.3 Å²	35.3	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-56.2	-52.1	175.1	-64.6	169.9	0	0	0	110.4	F184 L185 W189 W219 H332 E333 L338 I339 L340	F184-I336 HydrophobicContact CB-CG2 4.39Å; L185-I336 HydrophobicContact CD2-CB 4.13Å; L185-I336 HydrophobicContact CD2-CD1 4.27Å; L185-I336 HydrophobicContact CD2-CG2 4.32Å; W189-I336 HydrophobicContact CH2-CD1 3.72Å; W189-I336 HydrophobicContact CH2-CG1 4.11Å; W189-I336 HydrophobicContact CH2-CG2 4.42Å; W189-I336 HydrophobicContact CZ2-CD1 3.67Å; W189-I336 HydrophobicContact CZ2-CG1 4.45Å; W219-I336 HydrophobicContact CZ3-CG1 4.4Å; H332-I336 PolarHBondContact O-N 2.91Å; H332-I336 VanDerWaalsContact O-N 3.11Å; E333-I336 PolarHBondContact O-N 3.03Å; I336-L338 PolarHBondContact O-N 2.87Å; I336-I339 PolarHBondContact O-N 3Å; I336-L340 HydrophobicContact CG2-CD1 3.88Å; I336-L340 HydrophobicContact CG2-CG 4.43Å; I336-L340 WeakPolarHBondContact O-CG 3.48Å; I336-L340 PolarHBondContact O-N 3.41Å
337	V	96.2	Very high	85.3	Confident	0 Å²	0	28.3 Å²	28.3	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-62.7	-44.3	-176.8	179.2	0	0	0	0	111.2	I137 T141 T181 L185 E333 P334 Q335 I339 L340 F341 Y368	I137-V337 HydrophobicContact CG2-CG1 3.88Å; I137-V337 HydrophobicContact CG2-CG2 3.9Å; T141-V337 HydrophobicContact CG2-CB 4.3Å; T141-V337 HydrophobicContact CG2-CG2 3.83Å; T181-V337 HydrophobicContact CG2-CG2 4.49Å; L185-V337 HydrophobicContact CD1-CG2 3.81Å; L185-V337 HydrophobicContact CD2-CG2 3.65Å; L185-V337 HydrophobicContact CG-CG2 4.16Å; E333-V337 WeakPolarHBondContact O-CG2 3.41Å; E333-V337 PolarHBondContact O-N 3.35Å; P334-V337 PolarHBondContact O-N 3.18Å; Q335-V337 PolarHBondContact O-N 3.15Å; V337-I339 VanDerWaalsContact C-N 3.35Å; V337-I339 PolarHBondContact O-N 2.81Å; V337-L340 PolarHBondContact O-N 2.73Å; V337-F341 HydrophobicContact CG1-CD1 4.29Å; V337-F341 HydrophobicContact CG1-CD2 3.56Å; V337-F341 HydrophobicContact CG1-CE1 4.09Å; V337-F341 HydrophobicContact CG1-CE2 3.32Å; V337-F341 HydrophobicContact CG1-CG 4.06Å; V337-F341 HydrophobicContact CG1-CZ 3.61Å; V337-F341 WeakPolarHBondContact O-CB 3.39Å; V337-F341 VanDerWaalsContact O-CG 3.29Å; V337-F341 WeakPolarHBondContact O-CG 3.47Å; V337-F341 PolarHBondContact O-N 3.18Å; V337-Y368 HydrophobicContact CB-CE1 4.05Å; V337-Y368 HydrophobicContact CB-CE2 4.31Å; V337-Y368 HydrophobicContact CG1-CD1 3.87Å; V337-Y368 HydrophobicContact CG1-CD2 4.01Å; V337-Y368 HydrophobicContact CG1-CE1 3.63Å; V337-Y368 HydrophobicContact CG1-CE2 3.77Å; V337-Y368 HydrophobicContact CG1-CG 4.06Å
338	L	95.1	Very high	87.7	Confident	28 Å²	28	25 Å²	25	15%	0.147	14%	0.136	C	C	.	.	H	α-helix	trans	-60.9	-43.7	178.7	-174.2	60.1	0	0	0	111.8	P334 Q335 I336 T342 Y368 L369 L418 L424	P334-L338 VanDerWaalsContact O-CB 3.25Å; P334-L338 WeakPolarHBondContact O-CB 3.49Å; P334-L338 PolarHBondContact O-N 3Å; Q335-L338 PolarHBondContact O-N 3.42Å; I336-L338 PolarHBondContact O-N 2.87Å; L338-T342 WeakPolarHBondContact O-CB 3.47Å; L338-T342 PolarHBondContact O-N 3.2Å; L338-T342 PolarHBondContact O-OG1 3.29Å; L338-Y368 HydrophobicContact CB-CE1 3.99Å; L338-Y368 HydrophobicContact CD1-CD1 4.5Å; L338-Y368 HydrophobicContact CD1-CE1 4.15Å; L338-L369 HydrophobicContact CD1-CD2 4.46Å; L338-L418 HydrophobicContact CD1-CD2 3.93Å; L338-L424 HydrophobicContact CD2-CD1 3.95Å
339	I	96.1	Very high	90	Very high	2 Å²	2	18.2 Å²	18.2	1%	0.01	10%	0.102	C	C	.	.	H	α-helix	trans	-63.1	-49.9	179.4	-70	164.5	0	0	0	110.5	G212 F215 W304 Q335 I336 V337 T342 S343	G212-I339 WeakPolarHBondContact O-CG2 3.48Å; F215-I339 HydrophobicContact CB-CG2 4.37Å; F215-I339 HydrophobicContact CD1-CD1 3.79Å; F215-I339 HydrophobicContact CD1-CG2 4.29Å; F215-I339 HydrophobicContact CE1-CD1 3.88Å; W304-I339 HydrophobicContact CB-CD1 4.2Å; W304-I339 HydrophobicContact CB-CG1 4.04Å; W304-I339 HydrophobicContact CD2-CB 4.44Å; W304-I339 HydrophobicContact CD2-CG1 4.11Å; W304-I339 HydrophobicContact CD2-CG2 3.91Å; W304-I339 HydrophobicContact CE3-CG2 3.95Å; W304-I339 HydrophobicContact CG-CD1 4.42Å; W304-I339 HydrophobicContact CG-CG1 3.73Å; W304-I339 HydrophobicContact CG-CG2 4.41Å; W304-I339 HydrophobicContact CH2-CG2 4.37Å; W304-I339 HydrophobicContact CZ2-CG2 4.31Å; W304-I339 HydrophobicContact CZ3-CG2 4.19Å; Q335-I339 HydrophobicContact CG-CD1 3.71Å; Q335-I339 HydrophobicContact CG-CG1 4.45Å; Q335-I339 WeakPolarHBondContact O-CB 3.18Å; Q335-I339 WeakPolarHBondContact O-CD1 3.24Å; Q335-I339 WeakPolarHBondContact O-CG1 3.38Å; Q335-I339 PolarHBondContact O-N 2.88Å; I336-I339 PolarHBondContact O-N 3Å; V337-I339 VanDerWaalsContact C-N 3.35Å; V337-I339 PolarHBondContact O-N 2.81Å; I339-T342 PolarHBondContact O-N 3.32Å; I339-S343 WeakPolarHBondContact O-CB 3.44Å; I339-S343 PolarHBondContact O-N 3.03Å
340	L	98.2	Very high	92	Very high	3 Å²	3	18.2 Å²	18.2	2%	0.016	10%	0.098	C	C	.	.	H	α-helix	trans	-59.7	-49.6	179	-69.7	176.7	0	0	0	111.5	T181 F184 F209 L213 I336 V337 S343 N344	T181-L340 HydrophobicContact CG2-CD1 4.14Å; F184-L340 HydrophobicContact CD2-CD1 4.11Å; F209-L340 HydrophobicContact CD1-CB 4.19Å; F209-L340 WeakPolarHBondContact CD1-O 3.42Å; L213-L340 HydrophobicContact CB-CD2 3.86Å; L213-L340 HydrophobicContact CD1-CD2 4.47Å; I336-L340 HydrophobicContact CG2-CD1 3.88Å; I336-L340 HydrophobicContact CG2-CG 4.43Å; I336-L340 WeakPolarHBondContact O-CG 3.48Å; I336-L340 PolarHBondContact O-N 3.41Å; V337-L340 PolarHBondContact O-N 2.73Å; L340-S343 WeakPolarHBondContact O-CB 3.48Å; L340-S343 PolarHBondContact O-N 3.05Å; L340-N344 PolarHBondContact O-N 2.91Å
341	F	98.1	Very high	93.8	Very high	2 Å²	2	12.7 Å²	12.7	1%	0.009	7%	0.066	C	C	.	.	H	α-helix	trans	-70.3	-36.7	-176.6	-68.6	2.3	0	0	0	111.9	I137 F178 F209 V337 N344 F345 T365 Y368 L369	I137-F341 HydrophobicContact CG2-CZ 4.43Å; F178-F341 HydrophobicContact CE1-CE1 4.1Å; F178-F341 AromaticContact CE1-CZ 3.98Å; F178-F341 HydrophobicContact CE1-CZ 3.98Å; F209-F341 HydrophobicContact CE1-CD1 4.08Å; V337-F341 HydrophobicContact CG1-CD1 4.29Å; V337-F341 HydrophobicContact CG1-CD2 3.56Å; V337-F341 HydrophobicContact CG1-CE1 4.09Å; V337-F341 HydrophobicContact CG1-CE2 3.32Å; V337-F341 HydrophobicContact CG1-CG 4.06Å; V337-F341 HydrophobicContact CG1-CZ 3.61Å; V337-F341 WeakPolarHBondContact O-CB 3.39Å; V337-F341 VanDerWaalsContact O-CG 3.29Å; V337-F341 WeakPolarHBondContact O-CG 3.47Å; V337-F341 PolarHBondContact O-N 3.18Å; F341-N344 PolarHBondContact O-N 3.25Å; F341-F345 VanDerWaalsContact O-CB 3.25Å; F341-F345 WeakPolarHBondContact O-CB 3.31Å; F341-F345 PolarHBondContact O-N 3.01Å; F341-T365 HydrophobicContact CB-CG2 4.49Å; F341-T365 HydrophobicContact CD1-CG2 3.78Å; F341-T365 HydrophobicContact CD2-CG2 3.9Å; F341-T365 HydrophobicContact CE1-CG2 3.85Å; F341-T365 HydrophobicContact CE2-CG2 3.96Å; F341-T365 HydrophobicContact CG-CG2 3.8Å; F341-T365 HydrophobicContact CZ-CG2 3.93Å; F341-Y368 AromaticContact CD2-CD1 3.73Å; F341-Y368 HydrophobicContact CD2-CD1 3.73Å; F341-Y368 AromaticContact CD2-CG 3.81Å; F341-Y368 HydrophobicContact CD2-CG 3.81Å; F341-Y368 HydrophobicContact CE2-CD1 4.29Å; F341-Y368 AromaticContact CE2-CG 3.97Å; F341-Y368 HydrophobicContact CE2-CG 3.97Å; F341-L369 HydrophobicContact CB-CD2 3.82Å; F341-L369 HydrophobicContact CB-CG 4.31Å
342	T	97.7	Very high	94.9	Very high	2 Å²	2	11.6 Å²	11.6	1%	0.012	6%	0.059	C	C	.	.	H	α-helix	trans	-67.5	-39.8	176.1	-56.9	0	0	0	0	111.1	F299 W304 L338 I339 N344 F345 I346 L418	F299-T342 HydrophobicContact CD1-CG2 3.65Å; F299-T342 HydrophobicContact CE1-CG2 3.62Å; F299-T342 HydrophobicContact CG-CG2 4.35Å; F299-T342 HydrophobicContact CZ-CG2 4.29Å; W304-T342 HydrophobicContact CZ2-CG2 4.26Å; L338-T342 WeakPolarHBondContact O-CB 3.47Å; L338-T342 PolarHBondContact O-N 3.2Å; L338-T342 PolarHBondContact O-OG1 3.29Å; I339-T342 PolarHBondContact O-N 3.32Å; T342-N344 PolarHBondContact O-N 2.81Å; T342-F345 PolarHBondContact O-N 3.45Å; T342-I346 HydrophobicContact CG2-CD1 3.86Å; T342-I346 HydrophobicContact CG2-CG1 4.33Å; T342-I346 VanDerWaalsContact O-CG1 3.27Å; T342-I346 WeakPolarHBondContact O-CG1 3.29Å; T342-I346 PolarHBondContact O-N 3.23Å; T342-L418 HydrophobicContact CG2-CD1 4.3Å
343	S	98.5	Very high	95.5	Very high	0 Å²	0	10.7 Å²	10.7	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-55.7	-51.9	174.8	-176.3	0	0	0	0	111.2	L208 P211 G212 I339 L340 F345 I346 G347	L208-S343 CarbonylContact O-C 3.12Å; L208-S343 VanDerWaalsContact O-C 3.25Å; L208-S343 PolarHBondContact O-OG 3.35Å; P211-S343 WeakPolarHBondContact CD-OG 3.31Å; G212-S343 PolarHBondContact N-OG 3.43Å; G212-S343 VanDerWaalsContact N-OG 3.08Å; I339-S343 WeakPolarHBondContact O-CB 3.44Å; I339-S343 PolarHBondContact O-N 3.03Å; L340-S343 WeakPolarHBondContact O-CB 3.48Å; L340-S343 PolarHBondContact O-N 3.05Å; S343-F345 PolarHBondContact O-N 3.48Å; S343-I346 PolarHBondContact O-N 2.93Å; S343-G347 PolarHBondContact O-N 3.01Å
344	N	98.6	Very high	95.9	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-62.2	-44.1	177.6	176.4	61.3	0	0	0	112.5	L208 F209 L340 F341 T342 I346 G347 M348 W361	L208-N344 HydrophobicContact CB-CB 4.41Å; L208-N344 WeakPolarHBondContact CB-OD1 3Å; L208-N344 PolarHBondContact O-N 3.05Å; F209-N344 HydrophobicContact CD1-CB 3.71Å; F209-N344 HydrophobicContact CD2-CB 3.79Å; F209-N344 HydrophobicContact CE1-CB 3.37Å; F209-N344 HydrophobicContact CE2-CB 3.45Å; F209-N344 VanDerWaalsContact CE2-CB 3.45Å; F209-N344 WeakPolarHBondContact CE2-OD1 3.41Å; F209-N344 HydrophobicContact CG-CB 3.91Å; F209-N344 HydrophobicContact CZ-CB 3.22Å; F209-N344 VanDerWaalsContact CZ-ND2 3.3Å; F209-N344 WeakPolarHBondContact CZ-ND2 3.4Å; L340-N344 PolarHBondContact O-N 2.91Å; F341-N344 PolarHBondContact O-N 3.25Å; T342-N344 PolarHBondContact O-N 2.81Å; N344-I346 VanDerWaalsContact C-N 3.35Å; N344-I346 PolarHBondContact O-N 2.98Å; N344-G347 CarbonylContact O-C 3.4Å; N344-G347 VanDerWaalsContact O-CA 3.26Å; N344-G347 WeakPolarHBondContact O-CA 3.49Å; N344-G347 PolarHBondContact O-N 3.21Å; N344-M348 PolarHBondContact O-N 3.27Å; N344-W361 PolarHBondContact ND2-O 2.91Å
345	F	98.5	Very high	96	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-63.4	-39.2	-178.2	-175	-113.2	0	0	0	113	F341 T342 S343 G347 M348 C349 Y362 L366 L369 H411 I414 L415 L418	F341-F345 VanDerWaalsContact O-CB 3.25Å; F341-F345 WeakPolarHBondContact O-CB 3.31Å; F341-F345 PolarHBondContact O-N 3.01Å; T342-F345 PolarHBondContact O-N 3.45Å; S343-F345 PolarHBondContact O-N 3.48Å; F345-G347 PolarHBondContact O-N 2.82Å; F345-M348 WeakPolarHBondContact O-CB 3.34Å; F345-M348 PolarHBondContact O-N 3.39Å; F345-M348 VanDerWaalsContact O-N 3.12Å; F345-C349 PolarHBondContact O-N 3.28Å; F345-C349 PolarHBondContact O-SG 3.4Å; F345-Y362 AromaticContact CD2-CD2 3.87Å; F345-Y362 HydrophobicContact CD2-CD2 3.87Å; F345-Y362 HydrophobicContact CD2-CE2 4.29Å; F345-Y362 HydrophobicContact CE2-CD2 4.06Å; F345-Y362 HydrophobicContact CE2-CE2 4.02Å; F345-L366 HydrophobicContact CE2-CD2 4.17Å; F345-L369 HydrophobicContact CB-CD1 3.65Å; F345-L369 HydrophobicContact CD1-CD1 4.21Å; F345-L369 HydrophobicContact CD2-CD1 3.79Å; F345-L369 HydrophobicContact CG-CD1 3.61Å; F345-H411 AromaticContact CE2-CD2 3.82Å; F345-H411 HydrophobicContact CZ-CB 4.27Å; F345-H411 AromaticContact CZ-CD2 3.97Å; F345-I414 HydrophobicContact CD1-CG2 4.05Å; F345-I414 HydrophobicContact CE1-CB 3.64Å; F345-I414 HydrophobicContact CE1-CG2 3.31Å; F345-I414 HydrophobicContact CE2-CD1 4.27Å; F345-I414 HydrophobicContact CE2-CG2 4.42Å; F345-I414 HydrophobicContact CZ-CB 3.59Å; F345-I414 HydrophobicContact CZ-CD1 3.82Å; F345-I414 HydrophobicContact CZ-CG1 4.31Å; F345-I414 HydrophobicContact CZ-CG2 3.54Å; F345-L415 HydrophobicContact CD1-CD2 3.74Å; F345-L415 HydrophobicContact CD1-CG 4.21Å; F345-L415 HydrophobicContact CE1-CD2 3.83Å; F345-L415 HydrophobicContact CE1-CG 3.77Å; F345-L418 HydrophobicContact CD1-CD1 4.2Å
346	I	98.6	Very high	96.2	Very high	0 Å²	0	9.3 Å²	9.3	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-59.1	-41.4	171.1	-67.7	163.7	0	0	0	109.6	T295 L296 F299 T342 S343 N344 M348 C349 F350 L415	T295-I346 HydrophobicContact CG2-CD1 4.05Å; T295-I346 HydrophobicContact CG2-CG1 4.06Å; T295-I346 HydrophobicContact CG2-CG2 3.89Å; L296-I346 HydrophobicContact CD2-CB 4.15Å; L296-I346 HydrophobicContact CD2-CD1 3.9Å; L296-I346 HydrophobicContact CD2-CG2 4.1Å; L296-I346 HydrophobicContact CG-CG2 3.95Å; F299-I346 HydrophobicContact CB-CD1 4.22Å; F299-I346 HydrophobicContact CD1-CD1 4.47Å; F299-I346 HydrophobicContact CD2-CD1 3.68Å; F299-I346 HydrophobicContact CE2-CD1 4.11Å; F299-I346 HydrophobicContact CG-CD1 3.87Å; T342-I346 HydrophobicContact CG2-CD1 3.86Å; T342-I346 HydrophobicContact CG2-CG1 4.33Å; T342-I346 VanDerWaalsContact O-CG1 3.27Å; T342-I346 WeakPolarHBondContact O-CG1 3.29Å; T342-I346 PolarHBondContact O-N 3.23Å; S343-I346 PolarHBondContact O-N 2.93Å; N344-I346 VanDerWaalsContact C-N 3.35Å; N344-I346 PolarHBondContact O-N 2.98Å; I346-M348 PolarHBondContact O-N 3.29Å; I346-C349 PolarHBondContact O-N 3.47Å; I346-F350 HydrophobicContact CG2-CD2 3.88Å; I346-F350 HydrophobicContact CG2-CE2 3.99Å; I346-F350 WeakPolarHBondContact O-CD2 3.23Å; I346-F350 PolarHBondContact O-N 3.49Å; I346-L415 HydrophobicContact CG1-CD2 3.83Å
347	G	97.7	Very high	96.1	Very high	2 Å²	2	10.8 Å²	10.8	2%	0.021	5%	0.054	C	C	.	.	H	α-helix	trans	-55.5	-47.5	170.5	0	0	0	0	0	113.9	H292 S343 N344 F345 C349 F350 S351	H292-G347 VanDerWaalsContact CE1-CA 3.41Å; H292-G347 WeakPolarHBondContact CE1-CA 3.42Å; H292-G347 PolarHBondContact CE1-N 3.43Å; S343-G347 PolarHBondContact O-N 3.01Å; N344-G347 CarbonylContact O-C 3.4Å; N344-G347 VanDerWaalsContact O-CA 3.26Å; N344-G347 WeakPolarHBondContact O-CA 3.49Å; N344-G347 PolarHBondContact O-N 3.21Å; F345-G347 PolarHBondContact O-N 2.82Å; G347-C349 PolarHBondContact O-N 2.65Å; G347-F350 PolarHBondContact O-N 2.85Å; G347-S351 PolarHBondContact O-N 3.48Å; G347-S351 PolarHBondContact O-OG 2.91Å
348	M	97.6	Very high	96.1	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-61.7	-41.6	178.3	-63.8	-55.7	-65.8	0	0	112.4	L208 N344 F345 I346 F350 L354 W361 Y362	L208-M348 HydrophobicContact CD1-SD 4.21Å; N344-M348 PolarHBondContact O-N 3.27Å; F345-M348 WeakPolarHBondContact O-CB 3.34Å; F345-M348 PolarHBondContact O-N 3.39Å; F345-M348 VanDerWaalsContact O-N 3.12Å; I346-M348 PolarHBondContact O-N 3.29Å; M348-F350 VanDerWaalsContact C-N 3.35Å; M348-F350 PolarHBondContact O-N 2.97Å; M348-L354 HydrophobicContact CE-CD1 4.12Å; M348-L354 HydrophobicContact CE-CD2 3.48Å; M348-L354 VanDerWaalsContact CE-CD2 3.48Å; M348-L354 HydrophobicContact CE-CG 4.46Å; M348-L354 HydrophobicContact SD-CD2 4.35Å; M348-W361 HydrophobicContact CE-CB 4.36Å; M348-W361 HydrophobicContact CE-CE3 4.23Å; M348-W361 HydrophobicContact SD-CB 4.03Å; M348-W361 HydrophobicContact SD-CD2 4.49Å; M348-W361 HydrophobicContact SD-CE3 3.69Å; M348-Y362 HydrophobicContact CE-CD1 3.57Å; M348-Y362 HydrophobicContact CE-CE1 3.77Å; M348-Y362 HydrophobicContact CE-CG 4.32Å; M348-Y362 HydrophobicContact CG-CD1 4.17Å; M348-Y362 HydrophobicContact CG-CD2 4.42Å; M348-Y362 HydrophobicContact CG-CG 3.96Å; M348-Y362 HydrophobicContact SD-CD1 4.4Å
349	C	97.8	Very high	96.1	Very high	10 Å²	10	9.9 Å²	9.9	7%	0.068	5%	0.049	C	C	.	.	H	α-helix	trans	-64.9	-37.7	-177.9	-64	0	0	0	0	112.7	F345 I346 G347 L415	F345-C349 PolarHBondContact O-N 3.28Å; F345-C349 PolarHBondContact O-SG 3.4Å; I346-C349 PolarHBondContact O-N 3.47Å; G347-C349 PolarHBondContact O-N 2.65Å; C349-L415 HydrophobicContact CB-CD1 3.91Å
350	F	97.1	Very high	96.1	Very high	46 Å²	46	9.8 Å²	9.8	20%	0.202	5%	0.049	C	C	.	.	H	α-helix	trans	-99.7	1.1	-176.2	-65.7	-71.9	0	0	0	113.9	L288 A291 H292 T295 I346 G347 M348 R352	L288-F350 HydrophobicContact CD2-CD1 4.46Å; A291-F350 HydrophobicContact CB-CD1 3.75Å; A291-F350 HydrophobicContact CB-CE1 3.54Å; A291-F350 HydrophobicContact CB-CZ 4.24Å; H292-F350 HydrophobicContact CB-CB 3.72Å; H292-F350 HydrophobicContact CB-CD2 4.08Å; H292-F350 HydrophobicContact CB-CG 4.03Å; T295-F350 HydrophobicContact CG2-CE2 4.07Å; T295-F350 WeakPolarHBondContact OG1-CE2 3.47Å; T295-F350 WeakPolarHBondContact OG1-CZ 3.44Å; I346-F350 HydrophobicContact CG2-CD2 3.88Å; I346-F350 HydrophobicContact CG2-CE2 3.99Å; I346-F350 WeakPolarHBondContact O-CD2 3.23Å; I346-F350 PolarHBondContact O-N 3.49Å; G347-F350 PolarHBondContact O-N 2.85Å; M348-F350 VanDerWaalsContact C-N 3.35Å; M348-F350 PolarHBondContact O-N 2.97Å; F350-R352 PolarHBondContact O-N 3.35Å
351	S	94.9	Very high	96.1	Very high	25 Å²	25	10.8 Å²	10.8	18%	0.175	5%	0.052	C	C	.	.			trans	-59.4	129.1	173.3	-72.1	0	0	0	0	110.6	N270 W271 G347	N270-S351 PolarHBondContact ND2-O 3.49Å; W271-S351 PolarHBondContact NE1-O 3.02Å; G347-S351 PolarHBondContact O-N 3.48Å; G347-S351 PolarHBondContact O-OG 2.91Å
352	R	93.3	Very high	96	Very high	20 Å²	20	10.7 Å²	10.7	8%	0.075	5%	0.052	C	C	.	.	S	Bend	trans	-66.3	-38.9	178.8	-174.9	177.9	68.6	100.4	1.1	112.5	F279 F284 L288 F350	F279-R352 HydrophobicContact CE2-CG 4.4Å; F279-R352 WeakPolarHBondContact CE2-O 3.45Å; F279-R352 HydrophobicContact CZ-CG 4.48Å; F279-R352 WeakPolarHBondContact CZ-O 3.33Å; F279-R352 WeakPolarHBondContact O-CD 3.36Å; F279-R352 PolarHBondContact O-NH1 2.93Å; F284-R352 HydrophobicContact CD1-CG 4.4Å; F284-R352 HydrophobicContact CE1-CG 4.26Å; L288-R352 HydrophobicContact CD1-CB 3.77Å; L288-R352 HydrophobicContact CD1-CG 4.05Å; F350-R352 PolarHBondContact O-N 3.35Å
353	S	91.9	Very high	96	Very high	10 Å²	10	11.3 Å²	11.3	7%	0.07	6%	0.055	C	C	.	.			trans	-131.4	131.7	177.5	-170.8	0	0	0	0	110.1	F263	F263-S353 WeakPolarHBondContact CB-OG 3.41Å
354	L	94.3	Very high	95.9	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.055	C	C	.	.			trans	-118.8	112.9	172.2	-71.2	-178.2	0	0	0	109.3	T268 V269 N270 M348 F358 W394	T268-L354 CarbonylContact C-O 3.53Å; V269-L354 WeakPolarHBondContact CB-O 3.46Å; V269-L354 WeakPolarHBondContact CG2-O 3.07Å; V269-L354 PolarHBondContact N-O 3.43Å; N270-L354 HydrophobicContact CB-CB 4.39Å; N270-L354 HydrophobicContact CB-CD1 4.09Å; N270-L354 HydrophobicContact CB-CG 4.4Å; N270-L354 WeakPolarHBondContact OD1-CB 3.49Å; N270-L354 PolarHBondContact OD1-N 3.2Å; M348-L354 HydrophobicContact CE-CD1 4.12Å; M348-L354 HydrophobicContact CE-CD2 3.48Å; M348-L354 VanDerWaalsContact CE-CD2 3.48Å; M348-L354 HydrophobicContact CE-CG 4.46Å; M348-L354 HydrophobicContact SD-CD2 4.35Å; L354-F358 HydrophobicContact CD2-CB 4.47Å; L354-F358 HydrophobicContact CD2-CD2 4.16Å; L354-W394 HydrophobicContact CB-CH2 3.83Å; L354-W394 HydrophobicContact CB-CZ2 4.49Å; L354-W394 HydrophobicContact CD1-CH2 4.2Å; L354-W394 HydrophobicContact CD1-CZ2 4.09Å; L354-W394 HydrophobicContact CG-CH2 4.46Å
355	H	92.8	Very high	95.7	Very high	21 Å²	21	11.4 Å²	11.4	10%	0.097	6%	0.055	C	C	.	.			trans	-90.2	152.8	172.5	-68.5	170.9	0	0	0	111.2	F263 W267 Q357 F358 W394	F263-H355 VanDerWaalsContact CB-CE1 3.47Å; F263-H355 WeakPolarHBondContact CB-CE1 3.19Å; F263-H355 WeakPolarHBondContact CB-NE2 3.28Å; F263-H355 AromaticContact CD1-CE1 3.12Å; F263-H355 WeakPolarHBondContact CD1-CE1 3.33Å; F263-H355 AromaticContact CD1-ND1 3.56Å; F263-H355 AromaticContact CD1-NE2 3.98Å; F263-H355 AromaticContact CE1-CE1 3.96Å; F263-H355 AromaticContact CE1-ND1 3.97Å; F263-H355 AromaticContact CG-CE1 3.47Å; F263-H355 VanDerWaalsContact CG-CE1 3.47Å; F263-H355 WeakPolarHBondContact CG-CE1 3.3Å; F263-H355 AromaticContact CG-NE2 3.89Å; W267-H355 VanDerWaalsContact CB-CD2 3.48Å; W267-H355 WeakPolarHBondContact CB-CD2 3.49Å; W267-H355 VanDerWaalsContact CB-NE2 3.33Å; W267-H355 WeakPolarHBondContact CB-NE2 3.33Å; W267-H355 PolarHBondContact O-CD2 3.29Å; H355-Q357 PolarHBondContact O-N 3.13Å; H355-F358 HydrophobicContact CB-CD1 4.46Å; H355-F358 HydrophobicContact CB-CD2 4.09Å; H355-F358 HydrophobicContact CB-CE1 4.24Å; H355-F358 HydrophobicContact CB-CE2 3.84Å; H355-F358 HydrophobicContact CB-CG 4.36Å; H355-F358 HydrophobicContact CB-CZ 3.91Å; H355-F358 WeakPolarHBondContact O-CA 3.33Å; H355-F358 WeakPolarHBondContact O-CB 3.33Å; H355-F358 WeakPolarHBondContact O-CG 3.16Å; H355-F358 PolarHBondContact O-N 3.33Å; H355-W394 VanDerWaalsContact O-CZ3 3.27Å; H355-W394 WeakPolarHBondContact O-CZ3 3.49Å
356	Y	92.6	Very high	95.6	Very high	24 Å²	24	11.4 Å²	11.4	9%	0.094	6%	0.055	C	C	.	.	G	3₁₀ helix	trans	-50.2	-30.7	-174.5	-73.4	-66.2	0	0	0	116.5	V269 F358 W394 T396 Y397 S399	V269-Y356 HydrophobicContact CG2-CD1 3.48Å; V269-Y356 VanDerWaalsContact CG2-CD1 3.48Å; V269-Y356 HydrophobicContact CG2-CD2 4.24Å; V269-Y356 HydrophobicContact CG2-CE1 3.46Å; V269-Y356 VanDerWaalsContact CG2-CE1 3.46Å; V269-Y356 HydrophobicContact CG2-CE2 4.11Å; V269-Y356 HydrophobicContact CG2-CG 3.97Å; Y356-F358 VanDerWaalsContact C-N 3.32Å; Y356-W394 HydrophobicContact CD1-CE3 4.4Å; Y356-W394 VanDerWaalsContact CD1-O 3.24Å; Y356-W394 WeakPolarHBondContact CD1-O 3.46Å; Y356-W394 WeakPolarHBondContact CE1-O 3.37Å; Y356-T396 WeakPolarHBondContact CE1-O 3.37Å; Y356-T396 PolarHBondContact OH-O 3.21Å; Y356-Y397 HydrophobicContact CD2-CD2 4.11Å; Y356-Y397 HydrophobicContact CD2-CE2 4.46Å; Y356-Y397 HydrophobicContact CE1-CD2 4.48Å; Y356-Y397 AromaticContact CE2-CD2 3.43Å; Y356-Y397 HydrophobicContact CE2-CD2 3.43Å; Y356-Y397 VanDerWaalsContact CE2-CD2 3.43Å; Y356-Y397 AromaticContact CE2-CE2 3.91Å; Y356-Y397 HydrophobicContact CE2-CE2 3.91Å; Y356-Y397 AromaticContact CZ-CD2 3.61Å; Y356-S399 PolarHBondContact OH-N 2.9Å
357	Q	92.6	Very high	95.4	Very high	31 Å²	31	11.6 Å²	11.6	15%	0.145	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-70.6	-26.2	174.6	67.9	-139.1	60.8	0	0	113.3	F168 H355 Y359 V360	F168-Q357 HydrophobicContact CD2-CB 3.61Å; F168-Q357 HydrophobicContact CE2-CB 3.49Å; F168-Q357 VanDerWaalsContact CE2-CB 3.49Å; F168-Q357 HydrophobicContact CG-CB 4.28Å; F168-Q357 HydrophobicContact CZ-CB 4.1Å; H355-Q357 PolarHBondContact O-N 3.13Å; Q357-Y359 PolarHBondContact O-N 3.01Å; Q357-Y359 VanDerWaalsContact O-N 3.09Å; Q357-V360 WeakPolarHBondContact O-CG1 3.39Å; Q357-V360 PolarHBondContact O-N 2.96Å
358	F	95.4	Very high	95.2	Very high	6 Å²	6	11.5 Å²	11.5	3%	0.026	6%	0.055	C	C	.	.	G	3₁₀ helix	trans	-71.3	-5.4	-177.8	-53.3	-14.1	0	0	0	112.5	F263 L354 H355 Y356 V360 W361 W394	F263-F358 HydrophobicContact CE1-CZ 4.27Å; F263-F358 HydrophobicContact CE2-CE2 4.23Å; F263-F358 HydrophobicContact CE2-CZ 4.21Å; F263-F358 HydrophobicContact CZ-CE2 4.35Å; F263-F358 AromaticContact CZ-CZ 3.86Å; F263-F358 HydrophobicContact CZ-CZ 3.86Å; L354-F358 HydrophobicContact CD2-CB 4.47Å; L354-F358 HydrophobicContact CD2-CD2 4.16Å; H355-F358 HydrophobicContact CB-CD1 4.46Å; H355-F358 HydrophobicContact CB-CD2 4.09Å; H355-F358 HydrophobicContact CB-CE1 4.24Å; H355-F358 HydrophobicContact CB-CE2 3.84Å; H355-F358 HydrophobicContact CB-CG 4.36Å; H355-F358 HydrophobicContact CB-CZ 3.91Å; H355-F358 WeakPolarHBondContact O-CA 3.33Å; H355-F358 WeakPolarHBondContact O-CB 3.33Å; H355-F358 WeakPolarHBondContact O-CG 3.16Å; H355-F358 PolarHBondContact O-N 3.33Å; Y356-F358 VanDerWaalsContact C-N 3.32Å; F358-V360 PolarHBondContact O-N 3.31Å; F358-W361 HydrophobicContact CB-CD2 3.69Å; F358-W361 HydrophobicContact CB-CE3 3.88Å; F358-W361 HydrophobicContact CB-CG 4.21Å; F358-W361 HydrophobicContact CB-CH2 4.2Å; F358-W361 HydrophobicContact CB-CZ2 4.04Å; F358-W361 HydrophobicContact CB-CZ3 4.13Å; F358-W361 HydrophobicContact CD1-CD2 4.29Å; F358-W361 AromaticContact CD1-CE2 3.47Å; F358-W361 VanDerWaalsContact CD1-CE2 3.47Å; F358-W361 AromaticContact CD1-CH2 3.58Å; F358-W361 HydrophobicContact CD1-CH2 3.58Å; F358-W361 AromaticContact CD1-CZ2 3.07Å; F358-W361 HydrophobicContact CD1-CZ2 3.07Å; F358-W361 HydrophobicContact CD1-CZ3 4.36Å; F358-W361 AromaticContact CD1-NE1 3.92Å; F358-W361 HydrophobicContact CD2-CE3 4.48Å; F358-W361 AromaticContact CD2-CH2 3.6Å; F358-W361 HydrophobicContact CD2-CH2 3.6Å; F358-W361 HydrophobicContact CD2-CZ2 4Å; F358-W361 AromaticContact CD2-CZ3 3.87Å; F358-W361 HydrophobicContact CD2-CZ3 3.87Å; F358-W361 AromaticContact CE1-CH2 3.79Å; F358-W361 HydrophobicContact CE1-CH2 3.79Å; F358-W361 AromaticContact CE1-CZ2 3.42Å; F358-W361 HydrophobicContact CE1-CZ2 3.42Å; F358-W361 VanDerWaalsContact CE1-CZ2 3.42Å; F358-W361 AromaticContact CE2-CH2 3.81Å; F358-W361 HydrophobicContact CE2-CH2 3.81Å; F358-W361 HydrophobicContact CE2-CZ2 4.29Å; F358-W361 HydrophobicContact CE2-CZ3 4.41Å; F358-W361 HydrophobicContact CG-CD2 4.06Å; F358-W361 AromaticContact CG-CE2 3.69Å; F358-W361 HydrophobicContact CG-CE3 4.14Å; F358-W361 AromaticContact CG-CH2 3.53Å; F358-W361 HydrophobicContact CG-CH2 3.53Å; F358-W361 AromaticContact CG-CZ2 3.44Å; F358-W361 HydrophobicContact CG-CZ2 3.44Å; F358-W361 VanDerWaalsContact CG-CZ2 3.44Å; F358-W361 AromaticContact CG-CZ3 3.88Å; F358-W361 HydrophobicContact CG-CZ3 3.88Å; F358-W361 AromaticContact CZ-CH2 3.91Å; F358-W361 HydrophobicContact CZ-CH2 3.91Å; F358-W361 HydrophobicContact CZ-CZ2 4.04Å; F358-W361 WeakPolarHBondContact O-CB 3.48Å; F358-W361 VanDerWaalsContact O-CG 3.29Å; F358-W361 PolarHBondContact O-N 3.01Å; F358-W394 HydrophobicContact CB-CH2 4.33Å
359	Y	96.3	Very high	95	Very high	3 Å²	3	11.5 Å²	11.5	1%	0.012	6%	0.055	C	C	.	.	G	3₁₀ helix	trans	-57.4	-38.1	174.1	-171.4	-148.5	0	0	0	112	R158 I159 Q357 W361 Y362 F363 L366 I390 E391 W394	R158-Y359 HydrophobicContact CB-CD1 4.12Å; R158-Y359 HydrophobicContact CB-CE1 4.45Å; R158-Y359 HydrophobicContact CG-CD1 3.96Å; I159-Y359 HydrophobicContact CD1-CD1 3.84Å; I159-Y359 HydrophobicContact CD1-CE1 4.38Å; I159-Y359 HydrophobicContact CD1-CG 4.36Å; I159-Y359 HydrophobicContact CG1-CD1 4.37Å; I159-Y359 HydrophobicContact CG1-CE1 4.49Å; Q357-Y359 PolarHBondContact O-N 3.01Å; Q357-Y359 VanDerWaalsContact O-N 3.09Å; Y359-W361 PolarHBondContact O-N 3.02Å; Y359-W361 VanDerWaalsContact O-N 3.12Å; Y359-Y362 HydrophobicContact CD2-CD1 4.43Å; Y359-Y362 AromaticContact CD2-CE1 3.75Å; Y359-Y362 HydrophobicContact CD2-CE1 3.75Å; Y359-Y362 HydrophobicContact CE2-CE1 4.27Å; Y359-Y362 WeakPolarHBondContact O-CD1 3.46Å; Y359-Y362 PolarHBondContact O-N 3.34Å; Y359-F363 HydrophobicContact CD2-CB 4.22Å; Y359-F363 AromaticContact CE1-CD2 3.7Å; Y359-F363 HydrophobicContact CE1-CD2 3.7Å; Y359-F363 HydrophobicContact CE1-CE2 4.24Å; Y359-F363 HydrophobicContact CE1-CG 4.35Å; Y359-F363 HydrophobicContact CE2-CB 4.1Å; Y359-F363 AromaticContact CE2-CD2 3.91Å; Y359-F363 HydrophobicContact CE2-CD2 3.91Å; Y359-F363 HydrophobicContact CE2-CG 4.48Å; Y359-F363 AromaticContact CZ-CD2 3.36Å; Y359-F363 WeakPolarHBondContact O-CB 3.22Å; Y359-F363 PolarHBondContact O-N 3.47Å; Y359-F363 VanDerWaalsContact OH-CD2 3.26Å; Y359-F363 WeakPolarHBondContact OH-CD2 3.22Å; Y359-L366 HydrophobicContact CE2-CD1 4.33Å; Y359-I390 HydrophobicContact CE2-CG2 3.85Å; Y359-E391 WeakPolarHBondContact CE1-OE2 3.35Å; Y359-E391 VanDerWaalsContact CZ-OE2 3.25Å; Y359-E391 PolarHBondContact OH-OE2 3.4Å; Y359-W394 HydrophobicContact CD1-CB 4.09Å; Y359-W394 HydrophobicContact CD1-CG 4.13Å; Y359-W394 HydrophobicContact CD2-CB 4.31Å; Y359-W394 AromaticContact CD2-CD1 3.29Å; Y359-W394 AromaticContact CD2-CD2 3.65Å; Y359-W394 HydrophobicContact CD2-CD2 3.65Å; Y359-W394 AromaticContact CD2-CE2 3.55Å; Y359-W394 HydrophobicContact CD2-CE3 4.48Å; Y359-W394 AromaticContact CD2-CG 3.51Å; Y359-W394 HydrophobicContact CD2-CG 3.51Å; Y359-W394 HydrophobicContact CD2-CZ2 4.27Å; Y359-W394 AromaticContact CD2-NE1 3.35Å; Y359-W394 VanDerWaalsContact CD2-NE1 3.35Å; Y359-W394 HydrophobicContact CE1-CB 4.19Å; Y359-W394 HydrophobicContact CE1-CG 4.35Å; Y359-W394 HydrophobicContact CE2-CB 4.43Å; Y359-W394 AromaticContact CE2-CD1 3.25Å; Y359-W394 HydrophobicContact CE2-CD2 4.38Å; Y359-W394 AromaticContact CE2-CG 3.8Å; Y359-W394 HydrophobicContact CE2-CG 3.8Å; Y359-W394 AromaticContact CE2-NE1 3.6Å; Y359-W394 HydrophobicContact CG-CB 4.12Å; Y359-W394 AromaticContact CG-CD1 3.94Å; Y359-W394 AromaticContact CG-CD2 3.73Å; Y359-W394 HydrophobicContact CG-CD2 3.73Å; Y359-W394 HydrophobicContact CG-CE3 4.2Å; Y359-W394 AromaticContact CG-CG 3.67Å; Y359-W394 HydrophobicContact CG-CG 3.67Å; Y359-W394 AromaticContact CZ-CD1 3.85Å
360	V	96.6	Very high	94.8	Very high	1 Å²	1	11.2 Å²	11.2	1%	0.006	5%	0.053	C	C	.	.	G	3₁₀ helix	trans	-62.5	-20.9	179	75.7	0	0	0	0	113	I159 I162 F163 D170 M174 Q357 F358 Y362	I159-V360 HydrophobicContact CD1-CB 4.05Å; I159-V360 HydrophobicContact CD1-CG2 4.26Å; I162-V360 HydrophobicContact CD1-CB 4.49Å; I162-V360 HydrophobicContact CG2-CB 4.32Å; I162-V360 HydrophobicContact CG2-CG1 4.35Å; F163-V360 HydrophobicContact CE2-CG2 3.66Å; F163-V360 HydrophobicContact CZ-CG2 4.3Å; D170-V360 HydrophobicContact CB-CG1 3.51Å; M174-V360 HydrophobicContact CG-CG1 4.25Å; M174-V360 HydrophobicContact CG-CG2 4.47Å; Q357-V360 WeakPolarHBondContact O-CG1 3.39Å; Q357-V360 PolarHBondContact O-N 2.96Å; F358-V360 PolarHBondContact O-N 3.31Å; V360-Y362 PolarHBondContact O-N 2.89Å; V360-Y362 VanDerWaalsContact O-N 3.14Å
361	W	97.4	Very high	94.4	Very high	24 Å²	24	10.1 Å²	10.1	9%	0.091	5%	0.048	C	C	.	.	G	3₁₀ helix	trans	-64	-21.1	-178.6	-61.5	0	0	0	0	113.2	D170 M174 N205 L208 N344 M348 F358 Y359	D170-W361 PolarHBondContact OD1-NE1 3.06Å; M174-W361 WeakPolarHBondContact CE-O 3.34Å; N205-W361 HydrophobicContact CB-CD2 3.63Å; N205-W361 VanDerWaalsContact CB-CE2 3.45Å; N205-W361 HydrophobicContact CB-CE3 3.72Å; N205-W361 HydrophobicContact CB-CG 4.39Å; N205-W361 HydrophobicContact CB-CH2 3.55Å; N205-W361 HydrophobicContact CB-CZ2 3.42Å; N205-W361 VanDerWaalsContact CB-CZ2 3.42Å; N205-W361 HydrophobicContact CB-CZ3 3.69Å; N205-W361 VanDerWaalsContact ND2-CD1 3.27Å; N205-W361 VanDerWaalsContact ND2-CG 3.29Å; N205-W361 PolarHBondContact ND2-NE1 3.35Å; L208-W361 HydrophobicContact CD1-CE3 4.31Å; N344-W361 PolarHBondContact ND2-O 2.91Å; M348-W361 HydrophobicContact CE-CB 4.36Å; M348-W361 HydrophobicContact CE-CE3 4.23Å; M348-W361 HydrophobicContact SD-CB 4.03Å; M348-W361 HydrophobicContact SD-CD2 4.49Å; M348-W361 HydrophobicContact SD-CE3 3.69Å; F358-W361 HydrophobicContact CB-CD2 3.69Å; F358-W361 HydrophobicContact CB-CE3 3.88Å; F358-W361 HydrophobicContact CB-CG 4.21Å; F358-W361 HydrophobicContact CB-CH2 4.2Å; F358-W361 HydrophobicContact CB-CZ2 4.04Å; F358-W361 HydrophobicContact CB-CZ3 4.13Å; F358-W361 HydrophobicContact CD1-CD2 4.29Å; F358-W361 AromaticContact CD1-CE2 3.47Å; F358-W361 VanDerWaalsContact CD1-CE2 3.47Å; F358-W361 AromaticContact CD1-CH2 3.58Å; F358-W361 HydrophobicContact CD1-CH2 3.58Å; F358-W361 AromaticContact CD1-CZ2 3.07Å; F358-W361 HydrophobicContact CD1-CZ2 3.07Å; F358-W361 HydrophobicContact CD1-CZ3 4.36Å; F358-W361 AromaticContact CD1-NE1 3.92Å; F358-W361 HydrophobicContact CD2-CE3 4.48Å; F358-W361 AromaticContact CD2-CH2 3.6Å; F358-W361 HydrophobicContact CD2-CH2 3.6Å; F358-W361 HydrophobicContact CD2-CZ2 4Å; F358-W361 AromaticContact CD2-CZ3 3.87Å; F358-W361 HydrophobicContact CD2-CZ3 3.87Å; F358-W361 AromaticContact CE1-CH2 3.79Å; F358-W361 HydrophobicContact CE1-CH2 3.79Å; F358-W361 AromaticContact CE1-CZ2 3.42Å; F358-W361 HydrophobicContact CE1-CZ2 3.42Å; F358-W361 VanDerWaalsContact CE1-CZ2 3.42Å; F358-W361 AromaticContact CE2-CH2 3.81Å; F358-W361 HydrophobicContact CE2-CH2 3.81Å; F358-W361 HydrophobicContact CE2-CZ2 4.29Å; F358-W361 HydrophobicContact CE2-CZ3 4.41Å; F358-W361 HydrophobicContact CG-CD2 4.06Å; F358-W361 AromaticContact CG-CE2 3.69Å; F358-W361 HydrophobicContact CG-CE3 4.14Å; F358-W361 AromaticContact CG-CH2 3.53Å; F358-W361 HydrophobicContact CG-CH2 3.53Å; F358-W361 AromaticContact CG-CZ2 3.44Å; F358-W361 HydrophobicContact CG-CZ2 3.44Å; F358-W361 VanDerWaalsContact CG-CZ2 3.44Å; F358-W361 AromaticContact CG-CZ3 3.88Å; F358-W361 HydrophobicContact CG-CZ3 3.88Å; F358-W361 AromaticContact CZ-CH2 3.91Å; F358-W361 HydrophobicContact CZ-CH2 3.91Å; F358-W361 HydrophobicContact CZ-CZ2 4.04Å; F358-W361 WeakPolarHBondContact O-CB 3.48Å; F358-W361 VanDerWaalsContact O-CG 3.29Å; F358-W361 PolarHBondContact O-N 3.01Å; Y359-W361 PolarHBondContact O-N 3.02Å; Y359-W361 VanDerWaalsContact O-N 3.12Å
362	Y	96.8	Very high	94	Very high	0 Å²	0	10 Å²	10	0%	0	5%	0.047	C	C	.	.	T	Hydrogen-bonded Turn	trans	-146	-9.2	-176.5	81	-62	0	0	0	114.7	F345 M348 Y359 V360 H364 T365 L366 I390 W394 H411	F345-Y362 AromaticContact CD2-CD2 3.87Å; F345-Y362 HydrophobicContact CD2-CD2 3.87Å; F345-Y362 HydrophobicContact CD2-CE2 4.29Å; F345-Y362 HydrophobicContact CE2-CD2 4.06Å; F345-Y362 HydrophobicContact CE2-CE2 4.02Å; M348-Y362 HydrophobicContact CE-CD1 3.57Å; M348-Y362 HydrophobicContact CE-CE1 3.77Å; M348-Y362 HydrophobicContact CE-CG 4.32Å; M348-Y362 HydrophobicContact CG-CD1 4.17Å; M348-Y362 HydrophobicContact CG-CD2 4.42Å; M348-Y362 HydrophobicContact CG-CG 3.96Å; M348-Y362 HydrophobicContact SD-CD1 4.4Å; Y359-Y362 HydrophobicContact CD2-CD1 4.43Å; Y359-Y362 AromaticContact CD2-CE1 3.75Å; Y359-Y362 HydrophobicContact CD2-CE1 3.75Å; Y359-Y362 HydrophobicContact CE2-CE1 4.27Å; Y359-Y362 WeakPolarHBondContact O-CD1 3.46Å; Y359-Y362 PolarHBondContact O-N 3.34Å; V360-Y362 PolarHBondContact O-N 2.89Å; V360-Y362 VanDerWaalsContact O-N 3.14Å; Y362-H364 PolarHBondContact O-N 3.47Å; Y362-T365 WeakPolarHBondContact O-CA 3.47Å; Y362-T365 WeakPolarHBondContact O-CB 3.46Å; Y362-T365 PolarHBondContact O-N 3.12Å; Y362-T365 PolarHBondContact O-OG1 2.9Å; Y362-L366 HydrophobicContact CD2-CD1 4.06Å; Y362-L366 HydrophobicContact CD2-CD2 3.67Å; Y362-L366 HydrophobicContact CD2-CG 3.7Å; Y362-L366 HydrophobicContact CE2-CD1 3.75Å; Y362-L366 HydrophobicContact CE2-CD2 3.57Å; Y362-L366 HydrophobicContact CE2-CG 3.8Å; Y362-L366 PolarHBondContact O-N 3.32Å; Y362-L366 VanDerWaalsContact O-N 3.12Å; Y362-I390 WeakPolarHBondContact OH-CG2 3.37Å; Y362-W394 AromaticContact CE1-CE2 3.89Å; Y362-W394 AromaticContact CE1-CZ2 3.58Å; Y362-W394 HydrophobicContact CE1-CZ2 3.58Å; Y362-W394 AromaticContact CE1-NE1 3.8Å; Y362-W394 AromaticContact CZ-NE1 3.66Å; Y362-W394 PolarHBondContact OH-NE1 3.04Å; Y362-H411 AromaticContact CE2-NE2 3.62Å; Y362-H411 AromaticContact CZ-NE2 3.66Å; Y362-H411 PolarHBondContact OH-NE2 3.03Å; Y362-H411 VanDerWaalsContact OH-NE2 3.11Å
363	F	96.4	Very high	93	Very high	15 Å²	15	9.3 Å²	9.3	7%	0.066	5%	0.045	C	C	.	.	G	3₁₀ helix	trans	-46.1	-54.9	178.7	171	-103.6	0	0	0	113.3	V152 S156 I159 Y359 T365 L366	V152-F363 HydrophobicContact CG1-CE1 4.28Å; V152-F363 VanDerWaalsContact O-CE1 3.25Å; V152-F363 WeakPolarHBondContact O-CE1 3.3Å; V152-F363 WeakPolarHBondContact O-CZ 3.44Å; S156-F363 VanDerWaalsContact CB-CZ 3.48Å; I159-F363 HydrophobicContact CD1-CB 3.83Å; I159-F363 HydrophobicContact CD1-CD1 3.93Å; I159-F363 HydrophobicContact CD1-CG 3.85Å; I159-F363 HydrophobicContact CG1-CB 4.29Å; I159-F363 HydrophobicContact CG1-CD1 3.49Å; I159-F363 VanDerWaalsContact CG1-CD1 3.49Å; I159-F363 HydrophobicContact CG1-CD2 4.24Å; I159-F363 HydrophobicContact CG1-CE1 3.74Å; I159-F363 HydrophobicContact CG1-CE2 4.44Å; I159-F363 HydrophobicContact CG1-CG 3.73Å; I159-F363 HydrophobicContact CG1-CZ 4.2Å; Y359-F363 HydrophobicContact CD2-CB 4.22Å; Y359-F363 AromaticContact CE1-CD2 3.7Å; Y359-F363 HydrophobicContact CE1-CD2 3.7Å; Y359-F363 HydrophobicContact CE1-CE2 4.24Å; Y359-F363 HydrophobicContact CE1-CG 4.35Å; Y359-F363 HydrophobicContact CE2-CB 4.1Å; Y359-F363 AromaticContact CE2-CD2 3.91Å; Y359-F363 HydrophobicContact CE2-CD2 3.91Å; Y359-F363 HydrophobicContact CE2-CG 4.48Å; Y359-F363 AromaticContact CZ-CD2 3.36Å; Y359-F363 WeakPolarHBondContact O-CB 3.22Å; Y359-F363 PolarHBondContact O-N 3.47Å; Y359-F363 VanDerWaalsContact OH-CD2 3.26Å; Y359-F363 WeakPolarHBondContact OH-CD2 3.22Å; F363-T365 PolarHBondContact O-N 3.35Å; F363-T365 VanDerWaalsContact O-N 3.12Å; F363-L366 WeakPolarHBondContact O-CB 3.44Å; F363-L366 PolarHBondContact O-N 2.93Å
364	H	95.9	Very high	91.4	Very high	1 Å²	1	10 Å²	10	1%	0.005	6%	0.055	C	C	.	.	G	3₁₀ helix	trans	-67.3	-15.2	-178.3	-62.1	101.1	0	0	0	113.6	V134 Y138 F178 Y362	V134-H364 HydrophobicContact CG1-CB 4.11Å; V134-H364 HydrophobicContact CG2-CB 3.87Å; Y138-H364 PolarHBondContact OH-O 3.46Å; F178-H364 HydrophobicContact CE2-CB 4.15Å; F178-H364 HydrophobicContact CZ-CB 3.76Å; Y362-H364 PolarHBondContact O-N 3.47Å
365	T	96.3	Very high	89.8	Confident	0 Å²	0	12.3 Å²	12.3	0%	0	7%	0.069	C	C	.	.	G	3₁₀ helix	trans	-92	-21.3	178.7	74.6	0	0	0	0	112.8	F178 F341 Y362 F363 Y368 L369	F178-T365 HydrophobicContact CE1-CG2 4.2Å; F178-T365 HydrophobicContact CZ-CG2 4.19Å; F341-T365 HydrophobicContact CB-CG2 4.49Å; F341-T365 HydrophobicContact CD1-CG2 3.78Å; F341-T365 HydrophobicContact CD2-CG2 3.9Å; F341-T365 HydrophobicContact CE1-CG2 3.85Å; F341-T365 HydrophobicContact CE2-CG2 3.96Å; F341-T365 HydrophobicContact CG-CG2 3.8Å; F341-T365 HydrophobicContact CZ-CG2 3.93Å; Y362-T365 WeakPolarHBondContact O-CA 3.47Å; Y362-T365 WeakPolarHBondContact O-CB 3.46Å; Y362-T365 PolarHBondContact O-N 3.12Å; Y362-T365 PolarHBondContact O-OG1 2.9Å; F363-T365 PolarHBondContact O-N 3.35Å; F363-T365 VanDerWaalsContact O-N 3.12Å; T365-Y368 VanDerWaalsContact O-CB 3.31Å; T365-Y368 WeakPolarHBondContact O-CB 3.28Å; T365-Y368 PolarHBondContact O-N 3.14Å; T365-Y368 VanDerWaalsContact O-N 3.1Å; T365-L369 WeakPolarHBondContact O-CG 3.09Å; T365-L369 PolarHBondContact O-N 2.93Å; T365-L369 VanDerWaalsContact O-N 3.07Å
366	L	95.4	Very high	88.1	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-57	-46.6	-175.1	-79.8	171.2	0	0	0	114.3	F345 Y359 Y362 F363 Y368 L369 L370 L387 I390 I414	F345-L366 HydrophobicContact CE2-CD2 4.17Å; Y359-L366 HydrophobicContact CE2-CD1 4.33Å; Y362-L366 HydrophobicContact CD2-CD1 4.06Å; Y362-L366 HydrophobicContact CD2-CD2 3.67Å; Y362-L366 HydrophobicContact CD2-CG 3.7Å; Y362-L366 HydrophobicContact CE2-CD1 3.75Å; Y362-L366 HydrophobicContact CE2-CD2 3.57Å; Y362-L366 HydrophobicContact CE2-CG 3.8Å; Y362-L366 PolarHBondContact O-N 3.32Å; Y362-L366 VanDerWaalsContact O-N 3.12Å; F363-L366 WeakPolarHBondContact O-CB 3.44Å; F363-L366 PolarHBondContact O-N 2.93Å; L366-Y368 VanDerWaalsContact C-N 3.28Å; L366-Y368 PolarHBondContact O-N 3.32Å; L366-L369 PolarHBondContact O-N 2.94Å; L366-L370 PolarHBondContact O-N 2.89Å; L366-L387 HydrophobicContact CB-CD2 3.75Å; L366-I390 HydrophobicContact CD1-CD1 4.12Å; L366-I390 HydrophobicContact CD1-CG2 3.81Å; L366-I390 HydrophobicContact CD2-CD1 3.9Å; L366-I414 HydrophobicContact CD2-CD1 3.86Å
367	P	93.9	Very high	86.2	Confident	4 Å²	4	29 Å²	29	3%	0.026	14%	0.141	C	C	.	.	H	α-helix	trans	-58.4	-42.6	175.3	-23.2	32	0	0	0	112	Y138 V144 V148 V152 L369 L370 W371	Y138-P367 HydrophobicContact CE1-CB 4.34Å; Y138-P367 WeakPolarHBondContact OH-CB 3.32Å; V144-P367 HydrophobicContact CG1-CB 4.2Å; V148-P367 HydrophobicContact CG1-CB 3.73Å; V148-P367 HydrophobicContact CG1-CG 4.18Å; V152-P367 HydrophobicContact CG2-CG 3.57Å; P367-L369 VanDerWaalsContact C-N 3.35Å; P367-L369 PolarHBondContact O-N 3.19Å; P367-L370 PolarHBondContact O-N 3Å; P367-W371 HydrophobicContact CB-CE3 4.49Å; P367-W371 WeakPolarHBondContact O-CB 3.28Å; P367-W371 PolarHBondContact O-N 3.2Å
368	Y	93.9	Very high	84.6	Confident	1 Å²	1	28.7 Å²	28.7	0%	0.004	14%	0.14	C	C	.	.	H	α-helix	trans	-59.5	-46.4	178.3	-166.2	-87.6	0	0	0	111.9	Y138 T141 K143 V144 P334 V337 L338 F341 T365 L366 S372	Y138-Y368 HydrophobicContact CD1-CD2 4.17Å; Y138-Y368 AromaticContact CE1-CD2 3.85Å; Y138-Y368 HydrophobicContact CE1-CD2 3.85Å; Y138-Y368 HydrophobicContact CE1-CG 4.32Å; Y138-Y368 PolarHBondContact OH-N 3.22Å; T141-Y368 HydrophobicContact CG2-CE2 3.86Å; T141-Y368 WeakPolarHBondContact OG1-CE2 3.35Å; K143-Y368 HydrophobicContact CB-CE2 4.14Å; K143-Y368 HydrophobicContact CG-CE2 4.17Å; V144-Y368 HydrophobicContact CG2-CD2 4.49Å; P334-Y368 WeakPolarHBondContact CA-OH 3.16Å; P334-Y368 WeakPolarHBondContact CB-OH 3.21Å; P334-Y368 PolarHBondContact O-OH 2.97Å; V337-Y368 HydrophobicContact CB-CE1 4.05Å; V337-Y368 HydrophobicContact CB-CE2 4.31Å; V337-Y368 HydrophobicContact CG1-CD1 3.87Å; V337-Y368 HydrophobicContact CG1-CD2 4.01Å; V337-Y368 HydrophobicContact CG1-CE1 3.63Å; V337-Y368 HydrophobicContact CG1-CE2 3.77Å; V337-Y368 HydrophobicContact CG1-CG 4.06Å; L338-Y368 HydrophobicContact CB-CE1 3.99Å; L338-Y368 HydrophobicContact CD1-CD1 4.5Å; L338-Y368 HydrophobicContact CD1-CE1 4.15Å; F341-Y368 AromaticContact CD2-CD1 3.73Å; F341-Y368 HydrophobicContact CD2-CD1 3.73Å; F341-Y368 AromaticContact CD2-CG 3.81Å; F341-Y368 HydrophobicContact CD2-CG 3.81Å; F341-Y368 HydrophobicContact CE2-CD1 4.29Å; F341-Y368 AromaticContact CE2-CG 3.97Å; F341-Y368 HydrophobicContact CE2-CG 3.97Å; T365-Y368 VanDerWaalsContact O-CB 3.31Å; T365-Y368 WeakPolarHBondContact O-CB 3.28Å; T365-Y368 PolarHBondContact O-N 3.14Å; T365-Y368 VanDerWaalsContact O-N 3.1Å; L366-Y368 VanDerWaalsContact C-N 3.28Å; L366-Y368 PolarHBondContact O-N 3.32Å; Y368-S372 VanDerWaalsContact CE1-OG 3.3Å; Y368-S372 WeakPolarHBondContact CE1-OG 3.44Å; Y368-S372 WeakPolarHBondContact O-CB 3.44Å; Y368-S372 PolarHBondContact O-N 3.4Å; Y368-S372 PolarHBondContact O-OG 3.08Å
369	L	94.2	Very high	83.3	Confident	0 Å²	0	31 Å²	31	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-63.1	-45.3	179.7	-64.6	169.7	0	0	0	112.1	L338 F341 F345 T365 L366 P367 W371 S372 G373 I414 L418	L338-L369 HydrophobicContact CD1-CD2 4.46Å; F341-L369 HydrophobicContact CB-CD2 3.82Å; F341-L369 HydrophobicContact CB-CG 4.31Å; F345-L369 HydrophobicContact CB-CD1 3.65Å; F345-L369 HydrophobicContact CD1-CD1 4.21Å; F345-L369 HydrophobicContact CD2-CD1 3.79Å; F345-L369 HydrophobicContact CG-CD1 3.61Å; T365-L369 WeakPolarHBondContact O-CG 3.09Å; T365-L369 PolarHBondContact O-N 2.93Å; T365-L369 VanDerWaalsContact O-N 3.07Å; L366-L369 PolarHBondContact O-N 2.94Å; P367-L369 VanDerWaalsContact C-N 3.35Å; P367-L369 PolarHBondContact O-N 3.19Å; L369-W371 PolarHBondContact O-N 3.3Å; L369-S372 PolarHBondContact O-N 3.04Å; L369-G373 PolarHBondContact O-N 2.65Å; L369-I414 HydrophobicContact CB-CG2 4.07Å; L369-L418 HydrophobicContact CB-CD1 4.36Å; L369-L418 HydrophobicContact CD2-CD1 3.91Å; L369-L418 HydrophobicContact CD2-CD2 4.3Å; L369-L418 WeakPolarHBondContact O-CD2 3.36Å
370	L	91.9	Very high	82.3	Confident	3 Å²	3	35.8 Å²	35.8	2%	0.016	18%	0.183	C	C	.	.	H	α-helix	trans	-65.9	-37.6	-179.6	-82.1	166.4	0	0	0	113.5	L366 P367 R383 I386 L387 I414	L366-L370 PolarHBondContact O-N 2.89Å; P367-L370 PolarHBondContact O-N 3Å; L370-R383 HydrophobicContact CB-CB 4.49Å; L370-R383 HydrophobicContact CB-CG 4.39Å; L370-R383 HydrophobicContact CD2-CG 4.44Å; L370-R383 PolarHBondContact O-NE 3.44Å; L370-I386 HydrophobicContact CD1-CB 4.41Å; L370-I386 HydrophobicContact CD1-CG2 4.15Å; L370-I386 HydrophobicContact CD2-CB 4.25Å; L370-I386 HydrophobicContact CD2-CD1 3.87Å; L370-I386 HydrophobicContact CD2-CG2 4.02Å; L370-L387 HydrophobicContact CD1-CD1 4.44Å; L370-L387 HydrophobicContact CD1-CD2 3.59Å; L370-L387 HydrophobicContact CD1-CG 3.62Å; L370-I414 HydrophobicContact CD2-CD1 4.29Å; L370-I414 HydrophobicContact CD2-CG1 3.67Å; L370-I414 HydrophobicContact CG-CD1 4.31Å; L370-I414 HydrophobicContact CG-CG1 4.12Å
371	W	88.9	Confident	81.6	Confident	24 Å²	24	42.7 Å²	42.7	9%	0.091	22%	0.219	C	C	.	.	H	α-helix	trans	-87.2	-14	179.6	-88.4	-100.2	0	0	0	113.8	V144 P145 Y147 V148 P367 L369 H380 R383 V384 L387	V144-W371 HydrophobicContact CG1-CD2 4.39Å; V144-W371 HydrophobicContact CG1-CG 4.45Å; V144-W371 HydrophobicContact CG2-CB 3.87Å; V144-W371 HydrophobicContact CG2-CG 4.37Å; P145-W371 VanDerWaalsContact CG-NE1 3.3Å; Y147-W371 HydrophobicContact CE2-CZ2 4.39Å; Y147-W371 WeakPolarHBondContact OH-CZ2 3.16Å; V148-W371 HydrophobicContact CB-CH2 4.36Å; V148-W371 HydrophobicContact CB-CZ2 4.48Å; V148-W371 HydrophobicContact CG1-CE3 4.48Å; V148-W371 HydrophobicContact CG1-CH2 3.81Å; V148-W371 HydrophobicContact CG1-CZ2 4.38Å; V148-W371 HydrophobicContact CG1-CZ3 3.88Å; V148-W371 HydrophobicContact CG2-CD2 4.44Å; V148-W371 HydrophobicContact CG2-CH2 3.51Å; V148-W371 HydrophobicContact CG2-CZ2 3.25Å; V148-W371 HydrophobicContact CG2-CZ3 4.22Å; P367-W371 HydrophobicContact CB-CE3 4.49Å; P367-W371 WeakPolarHBondContact O-CB 3.28Å; P367-W371 PolarHBondContact O-N 3.2Å; L369-W371 PolarHBondContact O-N 3.3Å; W371-H380 AromaticContact NE1-ND1 3.79Å; W371-R383 HydrophobicContact CE3-CB 4.34Å; W371-R383 HydrophobicContact CH2-CB 3.67Å; W371-R383 HydrophobicContact CZ2-CB 4.06Å; W371-R383 HydrophobicContact CZ3-CB 3.82Å; W371-V384 HydrophobicContact CH2-CG2 4.25Å; W371-L387 HydrophobicContact CH2-CD1 4.23Å; W371-L387 HydrophobicContact CZ3-CD1 3.93Å
372	S	86.4	Confident	81.1	Confident	22 Å²	22	44.5 Å²	44.5	15%	0.154	23%	0.231	C	C	.	.	H	α-helix	trans	-84.6	-15.5	169.4	-58.1	0	0	0	0	112.8	Y368 L369 G374	Y368-S372 VanDerWaalsContact CE1-OG 3.3Å; Y368-S372 WeakPolarHBondContact CE1-OG 3.44Å; Y368-S372 WeakPolarHBondContact O-CB 3.44Å; Y368-S372 PolarHBondContact O-N 3.4Å; Y368-S372 PolarHBondContact O-OG 3.08Å; L369-S372 PolarHBondContact O-N 3.04Å; S372-G374 PolarHBondContact O-N 3.14Å
373	G	72.6	Confident	80.7	Confident	5 Å²	5	45.3 Å²	45.3	5%	0.052	23%	0.234	C	C	.	.	S	Bend	trans	-64	126.9	175	0	0	0	0	0	112.4	L369 V375	L369-G373 PolarHBondContact O-N 2.65Å; G373-V375 PolarHBondContact O-N 3.33Å; G373-V375 VanDerWaalsContact O-N 3.12Å
374	G	59.8	Low	80.3	Confident	26 Å²	26	46.3 Å²	46.3	27%	0.268	24%	0.241	S	C	.	.	S	Bend	trans	-80.6	10.3	-166.9	0	0	0	0	0	116.7	S372 K376 C417 A421	S372-G374 PolarHBondContact O-N 3.14Å; G374-K376 VanDerWaalsContact C-N 3.3Å; G374-K376 PolarHBondContact O-N 3.14Å; G374-C417 PolarHBondContact N-O 3.15Å; G374-A421 VanDerWaalsContact N-CB 3.31Å
375	V	60.5	Low	80.2	Confident	48 Å²	48	50.8 Å²	50.8	29%	0.291	26%	0.264	S	S	.	.			trans	-76.4	87.7	170.7	-169.8	0	0	0	0	107.7	G373 K377 L378	G373-V375 PolarHBondContact O-N 3.33Å; G373-V375 VanDerWaalsContact O-N 3.12Å; V375-K377 PolarHBondContact O-N 2.95Å; V375-L378 HydrophobicContact CB-CB 4.11Å; V375-L378 HydrophobicContact CG1-CB 4.13Å; V375-L378 HydrophobicContact CG1-CD1 4.35Å; V375-L378 WeakPolarHBondContact O-CB 3.3Å; V375-L378 PolarHBondContact O-N 3.37Å
376	K	57.3	Low	80.1	Confident	193 Å²	193	51 Å²	51	84%	0.839	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.3	-24.4	177.2	-67.1	-176.6	-178.6	178	0	112.8	G374	G374-K376 VanDerWaalsContact C-N 3.3Å; G374-K376 PolarHBondContact O-N 3.14Å
377	K	52.2	Low	79.9	Confident	202 Å²	202	51.9 Å²	51.9	88%	0.878	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.4	11.4	176.2	-72.1	-171	178.3	-177.2	0	114.3	V375 A379	V375-K377 PolarHBondContact O-N 2.95Å; K377-A379 PolarHBondContact O-N 3.46Å
378	L	58.8	Low	79.9	Confident	24 Å²	24	53.6 Å²	53.6	13%	0.126	29%	0.289	C	S	.	.	S	Bend	trans	-68.3	106.5	164.1	-150.4	67.9	0	0	0	105.5	V375 H380 L382 R383	V375-L378 HydrophobicContact CB-CB 4.11Å; V375-L378 HydrophobicContact CG1-CB 4.13Å; V375-L378 HydrophobicContact CG1-CD1 4.35Å; V375-L378 WeakPolarHBondContact O-CB 3.3Å; V375-L378 PolarHBondContact O-N 3.37Å; L378-H380 PolarHBondContact O-N 3.25Å; L378-L382 HydrophobicContact CD1-CD2 3.27Å; L378-L382 HydrophobicContact CD1-CG 4.44Å; L378-L382 HydrophobicContact CD2-CD2 4.2Å; L378-L382 HydrophobicContact CG-CB 4.23Å; L378-L382 HydrophobicContact CG-CD2 3.7Å; L378-L382 HydrophobicContact CG-CG 4.42Å; L378-R383 HydrophobicContact CD2-CG 3.87Å
379	A	67.8	Low	80	Confident	56 Å²	56	56.4 Å²	56.4	46%	0.463	30%	0.303	S	S	.	.			trans	-49.9	132.7	179	0	0	0	0	0	107.9	K377 L381 L382 R383	K377-A379 PolarHBondContact O-N 3.46Å; A379-L381 HydrophobicContact CB-CB 4.43Å; A379-L381 PolarHBondContact O-N 3.46Å; A379-L382 WeakPolarHBondContact O-CB 3.34Å; A379-L382 PolarHBondContact O-N 2.96Å; A379-R383 PolarHBondContact O-N 3.38Å
380	H	75.9	Confident	80	Confident	102 Å²	102	56.4 Å²	56.4	47%	0.472	30%	0.303	S	S	.	.	H	α-helix	trans	-49	-33.3	176.8	-75.2	-74.7	0	0	0	111.7	Y147 W371 L378 L382 R383 V384	Y147-H380 PolarHBondContact OH-ND1 2.91Å; W371-H380 AromaticContact NE1-ND1 3.79Å; L378-H380 PolarHBondContact O-N 3.25Å; H380-L382 PolarHBondContact O-N 2.79Å; H380-R383 PolarHBondContact O-N 2.89Å; H380-V384 WeakPolarHBondContact O-CG2 3.48Å; H380-V384 PolarHBondContact O-N 3.05Å; H380-V384 VanDerWaalsContact O-N 3.09Å
381	L	81.2	Confident	80.1	Confident	146 Å²	146	57.4 Å²	57.4	76%	0.764	31%	0.308	S	S	*	.	H	α-helix	trans	-55.9	-42.6	171.7	-63.2	176.1	0	0	0	113.5	A379 V384 L385	A379-L381 HydrophobicContact CB-CB 4.43Å; A379-L381 PolarHBondContact O-N 3.46Å; L381-V384 PolarHBondContact O-N 3.18Å; L381-L385 VanDerWaalsContact O-CB 3.28Å; L381-L385 WeakPolarHBondContact O-CB 3.46Å; L381-L385 PolarHBondContact O-N 3.23Å
382	L	86.4	Confident	80.3	Confident	63 Å²	63	61.3 Å²	61.3	33%	0.33	33%	0.33	S	S	.	.	H	α-helix	trans	-68.6	-38	178.4	-169.9	72.8	0	0	0	111.7	L378 A379 H380 V384 L385 I386	L378-L382 HydrophobicContact CD1-CD2 3.27Å; L378-L382 HydrophobicContact CD1-CG 4.44Å; L378-L382 HydrophobicContact CD2-CD2 4.2Å; L378-L382 HydrophobicContact CG-CB 4.23Å; L378-L382 HydrophobicContact CG-CD2 3.7Å; L378-L382 HydrophobicContact CG-CG 4.42Å; A379-L382 WeakPolarHBondContact O-CB 3.34Å; A379-L382 PolarHBondContact O-N 2.96Å; H380-L382 PolarHBondContact O-N 2.79Å; L382-V384 VanDerWaalsContact C-N 3.34Å; L382-V384 PolarHBondContact O-N 2.76Å; L382-L385 HydrophobicContact CD1-CD2 4.12Å; L382-L385 PolarHBondContact O-N 2.99Å; L382-I386 HydrophobicContact CD2-CD1 4.42Å; L382-I386 HydrophobicContact CG-CD1 4.09Å; L382-I386 HydrophobicContact CG-CG1 4.44Å; L382-I386 VanDerWaalsContact O-CG1 3.24Å; L382-I386 WeakPolarHBondContact O-CG1 3.38Å; L382-I386 PolarHBondContact O-N 3.33Å
383	R	89.3	Confident	80.8	Confident	17 Å²	17	60.4 Å²	60.4	6%	0.064	32%	0.323	C	S	.	.	H	α-helix	trans	-61.1	-45.6	175.4	-66.7	-177.1	175.1	119.3	-2.7	111.1	L370 W371 L378 A379 H380 I386 L387	L370-R383 HydrophobicContact CB-CB 4.49Å; L370-R383 HydrophobicContact CB-CG 4.39Å; L370-R383 HydrophobicContact CD2-CG 4.44Å; L370-R383 PolarHBondContact O-NE 3.44Å; W371-R383 HydrophobicContact CE3-CB 4.34Å; W371-R383 HydrophobicContact CH2-CB 3.67Å; W371-R383 HydrophobicContact CZ2-CB 4.06Å; W371-R383 HydrophobicContact CZ3-CB 3.82Å; L378-R383 HydrophobicContact CD2-CG 3.87Å; A379-R383 PolarHBondContact O-N 3.38Å; H380-R383 PolarHBondContact O-N 2.89Å; R383-I386 PolarHBondContact O-N 3.19Å; R383-L387 PolarHBondContact O-N 2.57Å
384	V	88.8	Confident	81.8	Confident	36 Å²	36	60.1 Å²	60.1	22%	0.218	32%	0.321	C	S	.	.	H	α-helix	trans	-65.9	-39.9	176.4	176.5	0	0	0	0	111	Y147 F151 W371 H380 L381 L382 I386 L387 G388	Y147-V384 HydrophobicContact CE2-CG2 4.08Å; F151-V384 HydrophobicContact CE1-CG1 4.24Å; F151-V384 HydrophobicContact CE2-CG1 4.05Å; F151-V384 HydrophobicContact CE2-CG2 4.21Å; F151-V384 HydrophobicContact CZ-CG1 3.74Å; W371-V384 HydrophobicContact CH2-CG2 4.25Å; H380-V384 WeakPolarHBondContact O-CG2 3.48Å; H380-V384 PolarHBondContact O-N 3.05Å; H380-V384 VanDerWaalsContact O-N 3.09Å; L381-V384 PolarHBondContact O-N 3.18Å; L382-V384 VanDerWaalsContact C-N 3.34Å; L382-V384 PolarHBondContact O-N 2.76Å; V384-I386 VanDerWaalsContact C-N 3.35Å; V384-I386 PolarHBondContact O-N 3.06Å; V384-L387 WeakPolarHBondContact O-CB 3.49Å; V384-L387 PolarHBondContact O-N 2.9Å; V384-G388 PolarHBondContact O-N 3.41Å
385	L	92.1	Very high	83.4	Confident	95 Å²	95	61.2 Å²	61.2	50%	0.497	32%	0.321	S	S	.	.	H	α-helix	trans	-60.3	-44	174.5	-179.8	62.6	0	0	0	111.4	L381 L382 L387 G388 L389	L381-L385 VanDerWaalsContact O-CB 3.28Å; L381-L385 WeakPolarHBondContact O-CB 3.46Å; L381-L385 PolarHBondContact O-N 3.23Å; L382-L385 HydrophobicContact CD1-CD2 4.12Å; L382-L385 PolarHBondContact O-N 2.99Å; L385-L387 PolarHBondContact O-N 3.35Å; L385-G388 PolarHBondContact O-N 3.3Å; L385-L389 HydrophobicContact CD1-CD1 4.26Å; L385-L389 HydrophobicContact CD1-CG 4.1Å; L385-L389 HydrophobicContact CG-CD1 4Å; L385-L389 HydrophobicContact CG-CG 4.27Å; L385-L389 WeakPolarHBondContact O-CB 3.38Å; L385-L389 WeakPolarHBondContact O-CG 3.24Å; L385-L389 PolarHBondContact O-N 3.18Å
386	I	93.9	Very high	85	Confident	3 Å²	3	60.7 Å²	60.7	2%	0.015	32%	0.318	C	S	.	.	H	α-helix	trans	-61.2	-44.5	176.6	-69.1	163.2	0	0	0	110.6	L370 L382 R383 V384 G388 L389 I390 C410 I413 I414	L370-I386 HydrophobicContact CD1-CB 4.41Å; L370-I386 HydrophobicContact CD1-CG2 4.15Å; L370-I386 HydrophobicContact CD2-CB 4.25Å; L370-I386 HydrophobicContact CD2-CD1 3.87Å; L370-I386 HydrophobicContact CD2-CG2 4.02Å; L382-I386 HydrophobicContact CD2-CD1 4.42Å; L382-I386 HydrophobicContact CG-CD1 4.09Å; L382-I386 HydrophobicContact CG-CG1 4.44Å; L382-I386 VanDerWaalsContact O-CG1 3.24Å; L382-I386 WeakPolarHBondContact O-CG1 3.38Å; L382-I386 PolarHBondContact O-N 3.33Å; R383-I386 PolarHBondContact O-N 3.19Å; V384-I386 VanDerWaalsContact C-N 3.35Å; V384-I386 PolarHBondContact O-N 3.06Å; I386-G388 VanDerWaalsContact C-N 3.33Å; I386-G388 PolarHBondContact O-N 3.5Å; I386-L389 PolarHBondContact O-N 3.44Å; I386-I390 HydrophobicContact CG2-CD1 3.82Å; I386-I390 HydrophobicContact CG2-CG1 4.42Å; I386-I390 WeakPolarHBondContact O-CB 3.36Å; I386-I390 VanDerWaalsContact O-CG1 3.26Å; I386-I390 WeakPolarHBondContact O-CG1 3.42Å; I386-I390 PolarHBondContact O-N 2.82Å; I386-C410 HydrophobicContact CG2-CB 4Å; I386-I413 HydrophobicContact CD1-CB 4.47Å; I386-I413 HydrophobicContact CD1-CG2 3.69Å; I386-I414 HydrophobicContact CG2-CD1 3.86Å; I386-I414 HydrophobicContact CG2-CG1 4.09Å
387	L	93.2	Very high	86.5	Confident	20 Å²	20	58.3 Å²	58.3	11%	0.105	30%	0.304	C	S	.	.	H	α-helix	trans	-58.3	-46	174	-71.1	176.9	0	0	0	111.5	V148 L366 L370 W371 R383 V384 L385 I390 E391	V148-L387 HydrophobicContact CG1-CD1 4.22Å; L366-L387 HydrophobicContact CB-CD2 3.75Å; L370-L387 HydrophobicContact CD1-CD1 4.44Å; L370-L387 HydrophobicContact CD1-CD2 3.59Å; L370-L387 HydrophobicContact CD1-CG 3.62Å; W371-L387 HydrophobicContact CH2-CD1 4.23Å; W371-L387 HydrophobicContact CZ3-CD1 3.93Å; R383-L387 PolarHBondContact O-N 2.57Å; V384-L387 WeakPolarHBondContact O-CB 3.49Å; V384-L387 PolarHBondContact O-N 2.9Å; L385-L387 PolarHBondContact O-N 3.35Å; L387-I390 PolarHBondContact O-N 3.49Å; L387-E391 WeakPolarHBondContact O-CB 3.44Å; L387-E391 PolarHBondContact O-N 2.95Å
388	G	92.6	Very high	88.4	Confident	40 Å²	40	52.4 Å²	52.4	41%	0.412	29%	0.286	S	S	.	.	H	α-helix	trans	-64.2	-41.4	178.8	0	0	0	0	0	113.5	V384 L385 I386 E391 L392	V384-G388 PolarHBondContact O-N 3.41Å; L385-G388 PolarHBondContact O-N 3.3Å; I386-G388 VanDerWaalsContact C-N 3.33Å; I386-G388 PolarHBondContact O-N 3.5Å; G388-E391 PolarHBondContact O-N 2.93Å; G388-L392 VanDerWaalsContact O-CB 3.31Å; G388-L392 WeakPolarHBondContact O-CB 3.44Å; G388-L392 PolarHBondContact O-N 2.86Å
389	L	95.4	Very high	90.1	Very high	60 Å²	60	51.5 Å²	51.5	31%	0.314	28%	0.282	S	S	.	.	H	α-helix	trans	-67.8	-37.7	176.7	-72.3	175.8	0	0	0	112	L385 I386 S393	L385-L389 HydrophobicContact CD1-CD1 4.26Å; L385-L389 HydrophobicContact CD1-CG 4.1Å; L385-L389 HydrophobicContact CG-CD1 4Å; L385-L389 HydrophobicContact CG-CG 4.27Å; L385-L389 WeakPolarHBondContact O-CB 3.38Å; L385-L389 WeakPolarHBondContact O-CG 3.24Å; L385-L389 PolarHBondContact O-N 3.18Å; I386-L389 PolarHBondContact O-N 3.44Å; L389-S393 WeakPolarHBondContact O-CB 3.38Å; L389-S393 PolarHBondContact O-N 2.8Å; L389-S393 PolarHBondContact O-OG 3.34Å
390	I	95.7	Very high	91.4	Very high	0 Å²	0	52 Å²	52	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-63.9	-50.7	172.5	-69.3	171.2	0	0	0	109.4	Y359 Y362 L366 I386 L387 L392 S393 W394 L407 C410 I414	Y359-I390 HydrophobicContact CE2-CG2 3.85Å; Y362-I390 WeakPolarHBondContact OH-CG2 3.37Å; L366-I390 HydrophobicContact CD1-CD1 4.12Å; L366-I390 HydrophobicContact CD1-CG2 3.81Å; L366-I390 HydrophobicContact CD2-CD1 3.9Å; I386-I390 HydrophobicContact CG2-CD1 3.82Å; I386-I390 HydrophobicContact CG2-CG1 4.42Å; I386-I390 WeakPolarHBondContact O-CB 3.36Å; I386-I390 VanDerWaalsContact O-CG1 3.26Å; I386-I390 WeakPolarHBondContact O-CG1 3.42Å; I386-I390 PolarHBondContact O-N 2.82Å; L387-I390 PolarHBondContact O-N 3.49Å; I390-L392 VanDerWaalsContact C-N 3.3Å; I390-L392 PolarHBondContact O-N 3.33Å; I390-S393 WeakPolarHBondContact O-CB 3.39Å; I390-S393 PolarHBondContact O-N 2.83Å; I390-S393 VanDerWaalsContact O-N 3.07Å; I390-W394 PolarHBondContact O-N 3.44Å; I390-L407 HydrophobicContact CG1-CD1 4.24Å; I390-L407 HydrophobicContact CG2-CD1 4.2Å; I390-C410 HydrophobicContact CD1-CB 4.04Å; I390-C410 HydrophobicContact CG1-CB 3.7Å; I390-I414 HydrophobicContact CD1-CD1 3.76Å
391	E	93.6	Very high	92.4	Very high	24 Å²	24	51.7 Å²	51.7	11%	0.112	28%	0.281	C	S	.	.	H	α-helix	trans	-55.9	-44.6	177.4	-173.7	66.4	-149.1	0	0	111.3	S156 Y359 L387 G388 S393 W394 N395	S156-E391 WeakPolarHBondContact CA-OE1 3.41Å; S156-E391 WeakPolarHBondContact CB-OE1 3.5Å; S156-E391 PolarHBondContact OG-OE1 3.31Å; S156-E391 PolarHBondContact OG-OE2 3.02Å; Y359-E391 WeakPolarHBondContact CE1-OE2 3.35Å; Y359-E391 VanDerWaalsContact CZ-OE2 3.25Å; Y359-E391 PolarHBondContact OH-OE2 3.4Å; L387-E391 WeakPolarHBondContact O-CB 3.44Å; L387-E391 PolarHBondContact O-N 2.95Å; G388-E391 PolarHBondContact O-N 2.93Å; E391-S393 PolarHBondContact O-N 3.27Å; E391-W394 PolarHBondContact O-N 3.45Å; E391-N395 WeakPolarHBondContact CG-ND2 3.44Å; E391-N395 WeakPolarHBondContact O-CB 3.29Å; E391-N395 PolarHBondContact O-N 3.43Å; E391-N395 PolarHBondContact O-ND2 3.01Å; E391-N395 PolarHBondContact OE1-ND2 3.26Å
392	L	93.6	Very high	93.2	Very high	106 Å²	106	49.2 Å²	49.2	56%	0.555	28%	0.276	S	S	*	.	H	α-helix	trans	-61.6	-44.1	175.9	-179.3	66.6	0	0	0	111.8	G388 I390 W394 N395 T396	G388-L392 VanDerWaalsContact O-CB 3.31Å; G388-L392 WeakPolarHBondContact O-CB 3.44Å; G388-L392 PolarHBondContact O-N 2.86Å; I390-L392 VanDerWaalsContact C-N 3.3Å; I390-L392 PolarHBondContact O-N 3.33Å; L392-W394 VanDerWaalsContact C-N 3.33Å; L392-W394 PolarHBondContact O-N 3.42Å; L392-N395 PolarHBondContact O-N 3.16Å; L392-N395 VanDerWaalsContact O-N 3.15Å; L392-T396 PolarHBondContact O-N 3.14Å; L392-T396 PolarHBondContact O-OG1 3.36Å
393	S	95.6	Very high	93.7	Very high	2 Å²	2	46.6 Å²	46.6	1%	0.014	26%	0.263	C	S	.	.	H	α-helix	trans	-62.8	-41.7	-179.6	-59	0	0	0	0	111.5	L389 I390 E391 S403	L389-S393 WeakPolarHBondContact O-CB 3.38Å; L389-S393 PolarHBondContact O-N 2.8Å; L389-S393 PolarHBondContact O-OG 3.34Å; I390-S393 WeakPolarHBondContact O-CB 3.39Å; I390-S393 PolarHBondContact O-N 2.83Å; I390-S393 VanDerWaalsContact O-N 3.07Å; E391-S393 PolarHBondContact O-N 3.27Å; S393-S403 WeakPolarHBondContact CB-O 3.3Å; S393-S403 PolarHBondContact OG-O 3.4Å; S393-S403 VanDerWaalsContact OG-O 3.13Å
394	W	94.8	Very high	94	Very high	0 Å²	0	45.8 Å²	45.8	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-69.9	-32.7	174.5	-76.1	101	0	0	0	112.5	R158 V269 L354 H355 Y356 F358 Y359 Y362 I390 E391 L392	R158-W394 PolarHBondContact NE-O 3.32Å; R158-W394 PolarHBondContact NH1-O 2.89Å; R158-W394 PolarHBondContact NH2-O 3.18Å; V269-W394 HydrophobicContact CB-CE3 4.27Å; V269-W394 HydrophobicContact CB-CZ3 4.18Å; V269-W394 HydrophobicContact CG1-CD2 4.18Å; V269-W394 HydrophobicContact CG1-CE3 4.08Å; V269-W394 HydrophobicContact CG1-CZ3 4.42Å; V269-W394 HydrophobicContact CG2-CE3 3.82Å; V269-W394 HydrophobicContact CG2-CZ3 3.78Å; L354-W394 HydrophobicContact CB-CH2 3.83Å; L354-W394 HydrophobicContact CB-CZ2 4.49Å; L354-W394 HydrophobicContact CD1-CH2 4.2Å; L354-W394 HydrophobicContact CD1-CZ2 4.09Å; L354-W394 HydrophobicContact CG-CH2 4.46Å; H355-W394 VanDerWaalsContact O-CZ3 3.27Å; H355-W394 WeakPolarHBondContact O-CZ3 3.49Å; Y356-W394 HydrophobicContact CD1-CE3 4.4Å; Y356-W394 VanDerWaalsContact CD1-O 3.24Å; Y356-W394 WeakPolarHBondContact CD1-O 3.46Å; Y356-W394 WeakPolarHBondContact CE1-O 3.37Å; F358-W394 HydrophobicContact CB-CH2 4.33Å; Y359-W394 HydrophobicContact CD1-CB 4.09Å; Y359-W394 HydrophobicContact CD1-CG 4.13Å; Y359-W394 HydrophobicContact CD2-CB 4.31Å; Y359-W394 AromaticContact CD2-CD1 3.29Å; Y359-W394 AromaticContact CD2-CD2 3.65Å; Y359-W394 HydrophobicContact CD2-CD2 3.65Å; Y359-W394 AromaticContact CD2-CE2 3.55Å; Y359-W394 HydrophobicContact CD2-CE3 4.48Å; Y359-W394 AromaticContact CD2-CG 3.51Å; Y359-W394 HydrophobicContact CD2-CG 3.51Å; Y359-W394 HydrophobicContact CD2-CZ2 4.27Å; Y359-W394 AromaticContact CD2-NE1 3.35Å; Y359-W394 VanDerWaalsContact CD2-NE1 3.35Å; Y359-W394 HydrophobicContact CE1-CB 4.19Å; Y359-W394 HydrophobicContact CE1-CG 4.35Å; Y359-W394 HydrophobicContact CE2-CB 4.43Å; Y359-W394 AromaticContact CE2-CD1 3.25Å; Y359-W394 HydrophobicContact CE2-CD2 4.38Å; Y359-W394 AromaticContact CE2-CG 3.8Å; Y359-W394 HydrophobicContact CE2-CG 3.8Å; Y359-W394 AromaticContact CE2-NE1 3.6Å; Y359-W394 HydrophobicContact CG-CB 4.12Å; Y359-W394 AromaticContact CG-CD1 3.94Å; Y359-W394 AromaticContact CG-CD2 3.73Å; Y359-W394 HydrophobicContact CG-CD2 3.73Å; Y359-W394 HydrophobicContact CG-CE3 4.2Å; Y359-W394 AromaticContact CG-CG 3.67Å; Y359-W394 HydrophobicContact CG-CG 3.67Å; Y359-W394 AromaticContact CZ-CD1 3.85Å; Y362-W394 AromaticContact CE1-CE2 3.89Å; Y362-W394 AromaticContact CE1-CZ2 3.58Å; Y362-W394 HydrophobicContact CE1-CZ2 3.58Å; Y362-W394 AromaticContact CE1-NE1 3.8Å; Y362-W394 AromaticContact CZ-NE1 3.66Å; Y362-W394 PolarHBondContact OH-NE1 3.04Å; I390-W394 PolarHBondContact O-N 3.44Å; E391-W394 PolarHBondContact O-N 3.45Å; L392-W394 VanDerWaalsContact C-N 3.33Å; L392-W394 PolarHBondContact O-N 3.42Å
395	N	93	Very high	94.5	Very high	49 Å²	49	45.9 Å²	45.9	26%	0.262	27%	0.265	S	S	.	.	H	α-helix	trans	-81.1	-13.5	179.8	-74.8	-55.4	0	0	0	115.6	R158 E391 L392 Y397	R158-N395 PolarHBondContact NE-OD1 3.5Å; E391-N395 WeakPolarHBondContact CG-ND2 3.44Å; E391-N395 WeakPolarHBondContact O-CB 3.29Å; E391-N395 PolarHBondContact O-N 3.43Å; E391-N395 PolarHBondContact O-ND2 3.01Å; E391-N395 PolarHBondContact OE1-ND2 3.26Å; L392-N395 PolarHBondContact O-N 3.16Å; L392-N395 VanDerWaalsContact O-N 3.15Å; N395-Y397 PolarHBondContact O-N 2.92Å
396	T	93.6	Very high	94.7	Very high	37 Å²	37	42.8 Å²	42.8	23%	0.227	25%	0.253	C	S	.	.			trans	-74.1	113.7	176.5	-56.9	0	0	0	0	110.4	Y356 L392 T400	Y356-T396 WeakPolarHBondContact CE1-O 3.37Å; Y356-T396 PolarHBondContact OH-O 3.21Å; L392-T396 PolarHBondContact O-N 3.14Å; L392-T396 PolarHBondContact O-OG1 3.36Å; T396-T400 HydrophobicContact CG2-CG2 4.11Å
397	Y	88.4	Confident	94.9	Very high	143 Å²	143	42.6 Å²	42.6	56%	0.561	25%	0.252	S	S	*	.	S	Bend	trans	-131.3	126.4	179.7	179.7	-95.1	0	0	0	112.3	W267 Y356 N395	W267-Y397 AromaticContact CE3-CE2 3.94Å; W267-Y397 HydrophobicContact CE3-CE2 3.94Å; W267-Y397 WeakPolarHBondContact CH2-OH 3.41Å; W267-Y397 AromaticContact CZ3-CE2 3.53Å; W267-Y397 HydrophobicContact CZ3-CE2 3.53Å; W267-Y397 AromaticContact CZ3-CZ 3.68Å; W267-Y397 WeakPolarHBondContact CZ3-OH 3.39Å; Y356-Y397 HydrophobicContact CD2-CD2 4.11Å; Y356-Y397 HydrophobicContact CD2-CE2 4.46Å; Y356-Y397 HydrophobicContact CE1-CD2 4.48Å; Y356-Y397 AromaticContact CE2-CD2 3.43Å; Y356-Y397 HydrophobicContact CE2-CD2 3.43Å; Y356-Y397 VanDerWaalsContact CE2-CD2 3.43Å; Y356-Y397 AromaticContact CE2-CE2 3.91Å; Y356-Y397 HydrophobicContact CE2-CE2 3.91Å; Y356-Y397 AromaticContact CZ-CD2 3.61Å; N395-Y397 PolarHBondContact O-N 2.92Å
398	P	92	Very high	95.1	Very high	77 Å²	77	43.2 Å²	43.2	50%	0.5	25%	0.254	S	S	.	.	S	Bend	cis	-63.2	161.2	-13.4	29.9	-35.6	0	0	0	111.2
399	S	94.6	Very high	95.4	Very high	5 Å²	5	45.3 Å²	45.3	4%	0.035	26%	0.259	C	S	.	.			trans	-64.4	146.5	179	65.3	0	0	0	0	111.4	T268 R272 Y356	T268-S399 WeakPolarHBondContact O-CB 3.07Å; T268-S399 PolarHBondContact O-OG 3Å; R272-S399 WeakPolarHBondContact CD-OG 3.49Å; R272-S399 WeakPolarHBondContact CG-OG 3.37Å; R272-S399 PolarHBondContact NE-O 3.16Å; Y356-S399 PolarHBondContact OH-N 2.9Å
400	T	96.3	Very high	95.5	Very high	67 Å²	67	42.5 Å²	42.5	41%	0.411	24%	0.244	S	C	.	.			trans	-109.7	164.7	176.4	66.8	0	0	0	0	110.7	T396 S402 S403 S404	T396-T400 HydrophobicContact CG2-CG2 4.11Å; T400-S402 PolarHBondContact O-N 3.16Å; T400-S403 PolarHBondContact N-OG 3.1Å; T400-S403 PolarHBondContact O-N 3.01Å; T400-S403 PolarHBondContact O-OG 3.44Å; T400-S403 VanDerWaalsContact O-OG 3.12Å; T400-S403 WeakPolarHBondContact OG1-CB 3.19Å; T400-S403 PolarHBondContact OG1-N 3.42Å; T400-S403 PolarHBondContact OG1-OG 2.91Å; T400-S404 VanDerWaalsContact O-CB 3.28Å; T400-S404 WeakPolarHBondContact O-CB 3.44Å; T400-S404 PolarHBondContact O-N 3.27Å
401	N	96.9	Very high	95.6	Very high	95 Å²	95	42.7 Å²	42.7	51%	0.508	25%	0.245	S	C	.	.	H	α-helix	trans	-56.7	-42.5	174.1	-66.3	-1.7	0	0	0	110.9	R272 F273 A405	R272-N401 PolarHBondContact O-OD1 3.16Å; F273-N401 HydrophobicContact CB-CB 4.03Å; N401-A405 VanDerWaalsContact O-CB 3.24Å; N401-A405 WeakPolarHBondContact O-CB 3.43Å; N401-A405 PolarHBondContact O-N 3.31Å
402	S	97	Very high	95.7	Very high	94 Å²	94	46.2 Å²	46.2	66%	0.657	26%	0.264	S	S	*	.	H	α-helix	trans	-67.7	-44.9	179.6	-52.8	0	0	0	0	112.6	T400 S404 A405 A406	T400-S402 PolarHBondContact O-N 3.16Å; S402-S404 VanDerWaalsContact C-N 3.3Å; S402-S404 PolarHBondContact O-N 2.74Å; S402-A405 PolarHBondContact O-N 3.15Å; S402-A406 VanDerWaalsContact O-CB 3.25Å; S402-A406 WeakPolarHBondContact O-CB 3.24Å; S402-A406 PolarHBondContact O-N 3.46Å
403	S	96.7	Very high	95.8	Very high	9 Å²	9	43.7 Å²	43.7	6%	0.063	25%	0.251	C	S	.	.	H	α-helix	trans	-64.9	-38.5	178.2	71.4	0	0	0	0	111.3	S393 T400 L407	S393-S403 WeakPolarHBondContact CB-O 3.3Å; S393-S403 PolarHBondContact OG-O 3.4Å; S393-S403 VanDerWaalsContact OG-O 3.13Å; T400-S403 PolarHBondContact N-OG 3.1Å; T400-S403 PolarHBondContact O-N 3.01Å; T400-S403 PolarHBondContact O-OG 3.44Å; T400-S403 VanDerWaalsContact O-OG 3.12Å; T400-S403 WeakPolarHBondContact OG1-CB 3.19Å; T400-S403 PolarHBondContact OG1-N 3.42Å; T400-S403 PolarHBondContact OG1-OG 2.91Å; S403-L407 PolarHBondContact O-N 3.21Å
404	S	97.1	Very high	95.8	Very high	0 Å²	0	43.6 Å²	43.6	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-70.6	-41.6	178.2	-158.1	0	0	0	0	112.6	V269 N270 W271 R272 T400 S402 L407 H408	V269-S404 VanDerWaalsContact O-CB 3.3Å; V269-S404 WeakPolarHBondContact O-CB 3.44Å; V269-S404 PolarHBondContact O-OG 2.92Å; N270-S404 WeakPolarHBondContact CA-OG 3.29Å; W271-S404 PolarHBondContact N-OG 3.34Å; R272-S404 PolarHBondContact N-OG 2.87Å; T400-S404 VanDerWaalsContact O-CB 3.28Å; T400-S404 WeakPolarHBondContact O-CB 3.44Å; T400-S404 PolarHBondContact O-N 3.27Å; S402-S404 VanDerWaalsContact C-N 3.3Å; S402-S404 PolarHBondContact O-N 2.74Å; S404-L407 PolarHBondContact O-N 3.46Å; S404-H408 PolarHBondContact O-CD2 3.5Å; S404-H408 VanDerWaalsContact O-CD2 3.3Å; S404-H408 PolarHBondContact O-N 3.33Å; S404-H408 VanDerWaalsContact O-N 3.17Å
405	A	97.4	Very high	95.8	Very high	38 Å²	38	44.6 Å²	44.6	31%	0.314	26%	0.255	S	S	.	.	H	α-helix	trans	-64.4	-42.5	173.9	0	0	0	0	0	111.5	F273 N401 S402 L407 H408 V409	F273-A405 HydrophobicContact CD1-CB 4.18Å; N401-A405 VanDerWaalsContact O-CB 3.24Å; N401-A405 WeakPolarHBondContact O-CB 3.43Å; N401-A405 PolarHBondContact O-N 3.31Å; S402-A405 PolarHBondContact O-N 3.15Å; A405-L407 VanDerWaalsContact C-N 3.34Å; A405-L407 PolarHBondContact O-N 2.68Å; A405-H408 PolarHBondContact O-N 3.05Å; A405-V409 WeakPolarHBondContact O-CG2 3.32Å; A405-V409 PolarHBondContact O-N 3.45Å
406	A	97.9	Very high	95.8	Very high	29 Å²	29	46.4 Å²	46.4	24%	0.24	26%	0.264	C	S	.	.	H	α-helix	trans	-59.2	-44.3	175.8	0	0	0	0	0	111.7	S402 H408 V409 C410	S402-A406 VanDerWaalsContact O-CB 3.25Å; S402-A406 WeakPolarHBondContact O-CB 3.24Å; S402-A406 PolarHBondContact O-N 3.46Å; A406-H408 VanDerWaalsContact C-N 3.35Å; A406-H408 PolarHBondContact O-N 2.89Å; A406-V409 PolarHBondContact O-N 2.91Å; A406-C410 WeakPolarHBondContact O-CB 3.44Å; A406-C410 PolarHBondContact O-N 2.86Å; A406-C410 PolarHBondContact O-SG 3.4Å; A406-C410 VanDerWaalsContact O-SG 3.35Å
407	L	97.8	Very high	95.7	Very high	0 Å²	0	45.2 Å²	45.2	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-57.1	-47.3	175.2	-177.4	62.5	0	0	0	111.9	V269 N270 I390 S403 S404 A405 C410 H411	V269-L407 HydrophobicContact CG1-CD2 3.82Å; N270-L407 HydrophobicContact CB-CD2 4.21Å; I390-L407 HydrophobicContact CG1-CD1 4.24Å; I390-L407 HydrophobicContact CG2-CD1 4.2Å; S403-L407 PolarHBondContact O-N 3.21Å; S404-L407 PolarHBondContact O-N 3.46Å; A405-L407 VanDerWaalsContact C-N 3.34Å; A405-L407 PolarHBondContact O-N 2.68Å; L407-C410 PolarHBondContact O-N 3.35Å; L407-H411 WeakPolarHBondContact CD1-NE2 3.43Å; L407-H411 WeakPolarHBondContact O-CB 3.24Å; L407-H411 PolarHBondContact O-N 3.04Å
408	H	97.8	Very high	95.8	Very high	32 Å²	32	38.9 Å²	38.9	15%	0.148	23%	0.233	C	C	.	.	H	α-helix	trans	-64.2	-41.3	178.5	-87.3	-69.7	0	0	0	112.9	W271 F273 S404 A405 A406 H411 L412	W271-H408 AromaticContact CD2-CE1 3.65Å; W271-H408 AromaticContact CD2-NE2 3.36Å; W271-H408 AromaticContact CE2-CE1 3.32Å; W271-H408 AromaticContact CE2-NE2 3.52Å; W271-H408 AromaticContact CE3-CE1 3.9Å; W271-H408 AromaticContact CE3-NE2 3.62Å; W271-H408 AromaticContact CG-NE2 3.76Å; W271-H408 AromaticContact CH2-CE1 3.58Å; W271-H408 AromaticContact CZ2-CE1 3.3Å; W271-H408 WeakPolarHBondContact CZ2-CE1 3.16Å; W271-H408 AromaticContact CZ2-NE2 3.93Å; W271-H408 AromaticContact CZ3-CE1 3.86Å; W271-H408 PolarHBondContact N-NE2 3.37Å; W271-H408 AromaticContact NE1-CE1 3.85Å; W271-H408 AromaticContact NE1-NE2 3.91Å; F273-H408 AromaticContact CE1-CD2 3.54Å; F273-H408 AromaticContact CZ-CD2 3.96Å; S404-H408 PolarHBondContact O-CD2 3.5Å; S404-H408 VanDerWaalsContact O-CD2 3.3Å; S404-H408 PolarHBondContact O-N 3.33Å; S404-H408 VanDerWaalsContact O-N 3.17Å; A405-H408 PolarHBondContact O-N 3.05Å; A406-H408 VanDerWaalsContact C-N 3.35Å; A406-H408 PolarHBondContact O-N 2.89Å; H408-H411 PolarHBondContact O-N 3.49Å; H408-L412 WeakPolarHBondContact O-CB 3.45Å; H408-L412 PolarHBondContact O-N 2.96Å
409	V	97.8	Very high	95.8	Very high	84 Å²	84	38.8 Å²	38.8	51%	0.509	22%	0.223	S	C	.	.	H	α-helix	trans	-62.1	-45.9	174.3	170.4	0	0	0	0	110.6	A405 A406 H411 L412 I413	A405-V409 WeakPolarHBondContact O-CG2 3.32Å; A405-V409 PolarHBondContact O-N 3.45Å; A406-V409 PolarHBondContact O-N 2.91Å; V409-H411 PolarHBondContact O-N 3.44Å; V409-L412 PolarHBondContact O-N 3.22Å; V409-I413 HydrophobicContact CG1-CD1 3.82Å; V409-I413 HydrophobicContact CG1-CG1 4.48Å; V409-I413 VanDerWaalsContact O-CG1 3.26Å; V409-I413 WeakPolarHBondContact O-CG1 3.35Å; V409-I413 PolarHBondContact O-N 3.01Å
410	C	97.4	Very high	95.5	Very high	2 Å²	2	43.9 Å²	43.9	1%	0.014	25%	0.249	C	C	.	.	H	α-helix	trans	-60.1	-44.4	175.3	-73.5	0	0	0	0	112	I386 I390 A406 L407 I413 I414	I386-C410 HydrophobicContact CG2-CB 4Å; I390-C410 HydrophobicContact CD1-CB 4.04Å; I390-C410 HydrophobicContact CG1-CB 3.7Å; A406-C410 WeakPolarHBondContact O-CB 3.44Å; A406-C410 PolarHBondContact O-N 2.86Å; A406-C410 PolarHBondContact O-SG 3.4Å; A406-C410 VanDerWaalsContact O-SG 3.35Å; L407-C410 PolarHBondContact O-N 3.35Å; C410-I413 PolarHBondContact O-N 3.18Å; C410-I414 VanDerWaalsContact O-CG1 3.3Å; C410-I414 WeakPolarHBondContact O-CG1 3.21Å; C410-I414 PolarHBondContact O-N 2.92Å
411	H	97.7	Very high	94.8	Very high	3 Å²	3	41.3 Å²	41.3	1%	0.014	24%	0.235	C	C	.	.	H	α-helix	trans	-60.9	-45.8	176.9	-77.3	-179.1	0	0	0	112.3	F345 Y362 L407 H408 V409 I414 L415	F345-H411 AromaticContact CE2-CD2 3.82Å; F345-H411 HydrophobicContact CZ-CB 4.27Å; F345-H411 AromaticContact CZ-CD2 3.97Å; Y362-H411 AromaticContact CE2-NE2 3.62Å; Y362-H411 AromaticContact CZ-NE2 3.66Å; Y362-H411 PolarHBondContact OH-NE2 3.03Å; Y362-H411 VanDerWaalsContact OH-NE2 3.11Å; L407-H411 WeakPolarHBondContact CD1-NE2 3.43Å; L407-H411 WeakPolarHBondContact O-CB 3.24Å; L407-H411 PolarHBondContact O-N 3.04Å; H408-H411 PolarHBondContact O-N 3.49Å; V409-H411 PolarHBondContact O-N 3.44Å; H411-I414 PolarHBondContact O-N 3.37Å; H411-L415 PolarHBondContact O-N 3.37Å
412	L	96.9	Very high	93.6	Very high	99 Å²	99	40 Å²	40	52%	0.518	23%	0.231	S	C	.	.	H	α-helix	trans	-61.3	-45	176.9	180	62.3	0	0	0	111.7	H408 V409 I414 L415 L416	H408-L412 WeakPolarHBondContact O-CB 3.45Å; H408-L412 PolarHBondContact O-N 2.96Å; V409-L412 PolarHBondContact O-N 3.22Å; L412-I414 VanDerWaalsContact C-N 3.34Å; L412-I414 PolarHBondContact O-N 3.28Å; L412-L415 PolarHBondContact O-N 3.07Å; L412-L416 HydrophobicContact CD1-CD1 4.13Å; L412-L416 HydrophobicContact CD1-CG 4.14Å; L412-L416 HydrophobicContact CG-CD1 3.95Å; L412-L416 HydrophobicContact CG-CG 4.39Å; L412-L416 WeakPolarHBondContact O-CB 3.12Å; L412-L416 VanDerWaalsContact O-CG 3.28Å; L412-L416 WeakPolarHBondContact O-CG 3.28Å; L412-L416 PolarHBondContact O-N 3.39Å
413	I	94.9	Very high	92	Very high	52 Å²	52	36.9 Å²	36.9	27%	0.267	21%	0.209	S	C	.	.	H	α-helix	trans	-59.8	-45.5	177.2	-68.3	165.2	0	0	0	110.5	I386 V409 C410 L416 C417	I386-I413 HydrophobicContact CD1-CB 4.47Å; I386-I413 HydrophobicContact CD1-CG2 3.69Å; V409-I413 HydrophobicContact CG1-CD1 3.82Å; V409-I413 HydrophobicContact CG1-CG1 4.48Å; V409-I413 VanDerWaalsContact O-CG1 3.26Å; V409-I413 WeakPolarHBondContact O-CG1 3.35Å; V409-I413 PolarHBondContact O-N 3.01Å; C410-I413 PolarHBondContact O-N 3.18Å; I413-L416 PolarHBondContact O-N 3.21Å; I413-C417 WeakPolarHBondContact O-CB 3.42Å; I413-C417 PolarHBondContact O-N 3.49Å; I413-C417 PolarHBondContact O-SG 3.37Å
414	I	95.3	Very high	90.1	Very high	1 Å²	1	39 Å²	39	1%	0.005	22%	0.22	C	C	.	.	H	α-helix	trans	-61.7	-47.8	177.6	-64.7	164.7	0	0	0	110.4	F345 L366 L369 L370 I386 I390 C410 H411 L412 L416 C417 L418	F345-I414 HydrophobicContact CD1-CG2 4.05Å; F345-I414 HydrophobicContact CE1-CB 3.64Å; F345-I414 HydrophobicContact CE1-CG2 3.31Å; F345-I414 HydrophobicContact CE2-CD1 4.27Å; F345-I414 HydrophobicContact CE2-CG2 4.42Å; F345-I414 HydrophobicContact CZ-CB 3.59Å; F345-I414 HydrophobicContact CZ-CD1 3.82Å; F345-I414 HydrophobicContact CZ-CG1 4.31Å; F345-I414 HydrophobicContact CZ-CG2 3.54Å; L366-I414 HydrophobicContact CD2-CD1 3.86Å; L369-I414 HydrophobicContact CB-CG2 4.07Å; L370-I414 HydrophobicContact CD2-CD1 4.29Å; L370-I414 HydrophobicContact CD2-CG1 3.67Å; L370-I414 HydrophobicContact CG-CD1 4.31Å; L370-I414 HydrophobicContact CG-CG1 4.12Å; I386-I414 HydrophobicContact CG2-CD1 3.86Å; I386-I414 HydrophobicContact CG2-CG1 4.09Å; I390-I414 HydrophobicContact CD1-CD1 3.76Å; C410-I414 VanDerWaalsContact O-CG1 3.3Å; C410-I414 WeakPolarHBondContact O-CG1 3.21Å; C410-I414 PolarHBondContact O-N 2.92Å; H411-I414 PolarHBondContact O-N 3.37Å; L412-I414 VanDerWaalsContact C-N 3.34Å; L412-I414 PolarHBondContact O-N 3.28Å; I414-L416 VanDerWaalsContact C-N 3.33Å; I414-L416 PolarHBondContact O-N 3.5Å; I414-C417 PolarHBondContact O-N 2.64Å; I414-L418 HydrophobicContact CG2-CD1 3.86Å; I414-L418 HydrophobicContact CG2-CG 4.31Å; I414-L418 VanDerWaalsContact O-CG 3.28Å; I414-L418 WeakPolarHBondContact O-CG 3.32Å; I414-L418 PolarHBondContact O-N 3.19Å
415	L	95.4	Very high	87.9	Confident	21 Å²	21	42.9 Å²	42.9	11%	0.11	24%	0.243	C	C	.	.	H	α-helix	trans	-57.9	-44.7	177.6	-78.9	179.6	0	0	0	111.9	F345 I346 C349 H411 L412 L418 W419	F345-L415 HydrophobicContact CD1-CD2 3.74Å; F345-L415 HydrophobicContact CD1-CG 4.21Å; F345-L415 HydrophobicContact CE1-CD2 3.83Å; F345-L415 HydrophobicContact CE1-CG 3.77Å; I346-L415 HydrophobicContact CG1-CD2 3.83Å; C349-L415 HydrophobicContact CB-CD1 3.91Å; H411-L415 PolarHBondContact O-N 3.37Å; L412-L415 PolarHBondContact O-N 3.07Å; L415-L418 PolarHBondContact O-N 3.36Å; L415-W419 VanDerWaalsContact O-CB 3.28Å; L415-W419 WeakPolarHBondContact O-CB 3.47Å; L415-W419 PolarHBondContact O-N 2.85Å
416	L	92.9	Very high	85.2	Confident	86 Å²	86	46.6 Å²	46.6	45%	0.45	25%	0.254	S	S	.	.	H	α-helix	trans	-65.3	-40.9	176.8	-70.6	173.1	0	0	0	111.7	L412 I413 I414 L418 W419 L420	L412-L416 HydrophobicContact CD1-CD1 4.13Å; L412-L416 HydrophobicContact CD1-CG 4.14Å; L412-L416 HydrophobicContact CG-CD1 3.95Å; L412-L416 HydrophobicContact CG-CG 4.39Å; L412-L416 WeakPolarHBondContact O-CB 3.12Å; L412-L416 VanDerWaalsContact O-CG 3.28Å; L412-L416 WeakPolarHBondContact O-CG 3.28Å; L412-L416 PolarHBondContact O-N 3.39Å; I413-L416 PolarHBondContact O-N 3.21Å; I414-L416 VanDerWaalsContact C-N 3.33Å; I414-L416 PolarHBondContact O-N 3.5Å; L416-L418 VanDerWaalsContact C-N 3.35Å; L416-L418 PolarHBondContact O-N 3.18Å; L416-W419 CarbonylContact O-C 3.54Å; L416-W419 PolarHBondContact O-N 3.33Å; L416-L420 WeakPolarHBondContact O-CB 3.27Å; L416-L420 VanDerWaalsContact O-CG 3.25Å; L416-L420 WeakPolarHBondContact O-CG 3.32Å; L416-L420 PolarHBondContact O-N 3.44Å
417	C	90.8	Very high	82.3	Confident	12 Å²	12	54.2 Å²	54.2	8%	0.081	28%	0.282	C	S	.	.	H	α-helix	trans	-63.9	-39	176.2	-74.5	0	0	0	0	112.7	G374 I413 I414 A421	G374-C417 PolarHBondContact N-O 3.15Å; I413-C417 WeakPolarHBondContact O-CB 3.42Å; I413-C417 PolarHBondContact O-N 3.49Å; I413-C417 PolarHBondContact O-SG 3.37Å; I414-C417 PolarHBondContact O-N 2.64Å; C417-A421 PolarHBondContact O-N 3.36Å
418	L	92.1	Very high	79.3	Confident	10 Å²	10	61.8 Å²	61.8	5%	0.052	32%	0.315	C	S	.	.	H	α-helix	trans	-68.7	-41.4	173.8	-67.6	170	0	0	0	110.9	F299 L338 T342 F345 L369 I414 L415 L416 L420 A421	F299-L418 HydrophobicContact CE1-CB 4.08Å; F299-L418 HydrophobicContact CZ-CB 4.2Å; L338-L418 HydrophobicContact CD1-CD2 3.93Å; T342-L418 HydrophobicContact CG2-CD1 4.3Å; F345-L418 HydrophobicContact CD1-CD1 4.2Å; L369-L418 HydrophobicContact CB-CD1 4.36Å; L369-L418 HydrophobicContact CD2-CD1 3.91Å; L369-L418 HydrophobicContact CD2-CD2 4.3Å; L369-L418 WeakPolarHBondContact O-CD2 3.36Å; I414-L418 HydrophobicContact CG2-CD1 3.86Å; I414-L418 HydrophobicContact CG2-CG 4.31Å; I414-L418 VanDerWaalsContact O-CG 3.28Å; I414-L418 WeakPolarHBondContact O-CG 3.32Å; I414-L418 PolarHBondContact O-N 3.19Å; L415-L418 PolarHBondContact O-N 3.36Å; L416-L418 VanDerWaalsContact C-N 3.35Å; L416-L418 PolarHBondContact O-N 3.18Å; L418-L420 VanDerWaalsContact C-N 3.33Å; L418-L420 PolarHBondContact O-N 2.73Å; L418-A421 WeakPolarHBondContact O-CB 3.38Å; L418-A421 PolarHBondContact O-N 2.87Å
419	W	91.8	Very high	76.2	Confident	76 Å²	76	68.5 Å²	68.5	29%	0.288	35%	0.346	S	S	.	.	H	α-helix	trans	-67.7	-30.5	176	-176	-98.5	0	0	0	112.7	L298 F299 R302 R303 L415 L416 A421	L298-W419 HydrophobicContact CB-CH2 3.89Å; L298-W419 HydrophobicContact CB-CZ3 3.89Å; F299-W419 AromaticContact CD2-CE3 3.9Å; F299-W419 HydrophobicContact CD2-CE3 3.9Å; F299-W419 HydrophobicContact CD2-CZ3 4.07Å; F299-W419 HydrophobicContact CE1-CE3 4.44Å; F299-W419 AromaticContact CE2-CE3 3.69Å; F299-W419 HydrophobicContact CE2-CE3 3.69Å; F299-W419 HydrophobicContact CE2-CZ3 4.31Å; F299-W419 HydrophobicContact CG-CE3 4.4Å; F299-W419 HydrophobicContact CG-CZ3 4.46Å; F299-W419 HydrophobicContact CZ-CB 4.17Å; F299-W419 AromaticContact CZ-CE3 3.99Å; F299-W419 HydrophobicContact CZ-CE3 3.99Å; R302-W419 HydrophobicContact CB-CH2 3.8Å; R302-W419 HydrophobicContact CB-CZ3 4.27Å; R302-W419 HydrophobicContact CG-CH2 3.97Å; R303-W419 HydrophobicContact CG-CE3 3.83Å; R303-W419 HydrophobicContact CG-CZ3 3.99Å; R303-W419 PolarHBondContact NE-O 3Å; R303-W419 PolarHBondContact NH1-O 3.41Å; R303-W419 PolarHBondContact NH2-O 3.4Å; L415-W419 VanDerWaalsContact O-CB 3.28Å; L415-W419 WeakPolarHBondContact O-CB 3.47Å; L415-W419 PolarHBondContact O-N 2.85Å; L416-W419 CarbonylContact O-C 3.54Å; L416-W419 PolarHBondContact O-N 3.33Å; W419-A421 VanDerWaalsContact C-N 3.34Å
420	L	88.1	Confident	73	Confident	111 Å²	111	71.2 Å²	71.2	58%	0.581	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.4	-3.4	178.5	-66.4	173.8	0	0	0	112.5	L416 L418	L416-L420 WeakPolarHBondContact O-CB 3.27Å; L416-L420 VanDerWaalsContact O-CG 3.25Å; L416-L420 WeakPolarHBondContact O-CG 3.32Å; L416-L420 PolarHBondContact O-N 3.44Å; L418-L420 VanDerWaalsContact C-N 3.33Å; L418-L420 PolarHBondContact O-N 2.73Å
421	A	82	Confident	70	Confident	13 Å²	13	77.1 Å²	77.1	11%	0.107	39%	0.389	C	S	.	.	S	Bend	trans	-63.2	131.6	179	0	0	0	0	0	110.7	R303 G374 C417 L418 W419	R303-A421 PolarHBondContact NH1-O 3.37Å; G374-A421 VanDerWaalsContact N-CB 3.31Å; C417-A421 PolarHBondContact O-N 3.36Å; L418-A421 WeakPolarHBondContact O-CB 3.38Å; L418-A421 PolarHBondContact O-N 2.87Å; W419-A421 VanDerWaalsContact C-N 3.34Å
422	P	71.1	Confident	66.9	Low	67 Å²	67	81.8 Å²	81.8	44%	0.435	42%	0.418	S	S	.	.	P	Polyproline II helix	trans	-60.1	144.5	172.6	24.1	-25.4	0	0	0	108.5	L424	P422-L424 PolarHBondContact O-N 3.35Å
423	P	64.2	Low	63.9	Low	29 Å²	29	83.2 Å²	83.2	19%	0.188	43%	0.426	C	S	.	.	P	Polyproline II helix	trans	-50.7	136.4	173.8	-21.5	31.1	0	0	0	109.7	P307 T425 E426	P307-P423 HydrophobicContact CG-CB 3.97Å; P307-P423 HydrophobicContact CG-CG 4.2Å; P423-T425 PolarHBondContact O-N 3.36Å; P423-E426 PolarHBondContact O-N 3.48Å
424	L	55.1	Low	61.1	Low	55 Å²	55	89.4 Å²	89.4	29%	0.288	45%	0.451	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.1	-24.4	-174.3	-77.4	163.5	0	0	0	113.1	Q335 L338 P422	Q335-L424 HydrophobicContact CB-CD1 4.1Å; Q335-L424 HydrophobicContact CG-CD1 4.48Å; L338-L424 HydrophobicContact CD2-CD1 3.95Å; P422-L424 PolarHBondContact O-N 3.35Å
425	T	52.5	Low	58.3	Low	80 Å²	80	96.8 Å²	96.8	49%	0.491	49%	0.486	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81	-6.5	177.6	38.9	0	0	0	0	115.4	P307 P423 K427	P307-T425 WeakPolarHBondContact CD-OG1 3.43Å; P423-T425 PolarHBondContact O-N 3.36Å; T425-K427 VanDerWaalsContact C-N 3.31Å; T425-K427 PolarHBondContact O-N 3.06Å
426	E	40.3	Very low	55.5	Low	117 Å²	117	102.6 Å²	102.6	55%	0.547	52%	0.517	S	S	.	.			trans	-90	24.6	-176	-105.4	-175.8	-167.1	0	0	114.5	P423 K428	P423-E426 PolarHBondContact O-N 3.48Å; E426-K428 PolarHBondContact O-N 3.32Å
427	K	36.1	Very low	53	Low	189 Å²	189	107.5 Å²	107.5	82%	0.822	53%	0.534	S	S	*	.			trans	-73.5	82.7	168.6	-122.2	-175.5	-177.3	-175.5	0	109.1	T425 E429	T425-K427 VanDerWaalsContact C-N 3.31Å; T425-K427 PolarHBondContact O-N 3.06Å; K427-E429 PolarHBondContact O-N 3.39Å
428	K	34.6	Very low	50.7	Low	159 Å²	159	117.1 Å²	117.1	69%	0.691	57%	0.569	S	S	*	*			trans	-42	132.6	173.3	-78.4	177.5	168.5	-177.8	0	111.4	E426 H430	E426-K428 PolarHBondContact O-N 3.32Å; K428-H430 HydrophobicContact CB-CB 4.22Å; K428-H430 PolarHBondContact O-N 3.13Å
429	E	33.4	Very low	48.2	Very low	173 Å²	173	128.9 Å²	128.9	81%	0.808	62%	0.623	S	S	*	*	S	Bend	trans	-55.5	23.4	165.9	-67.8	167.7	135.9	0	0	114.6	K427 T431	K427-E429 PolarHBondContact O-N 3.39Å; E429-T431 PolarHBondContact O-N 3.19Å; E429-T431 VanDerWaalsContact O-N 3.1Å
430	H	31.4	Very low	46	Very low	140 Å²	140	131.5 Å²	131.5	65%	0.648	64%	0.64	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.2	9.1	-168.4	-104.9	-27.6	0	0	0	115.8	K428	K428-H430 HydrophobicContact CB-CB 4.22Å; K428-H430 PolarHBondContact O-N 3.13Å
431	T	33.8	Very low	43.8	Very low	126 Å²	126	132.6 Å²	132.6	77%	0.773	64%	0.643	S	S	*	*	T	Hydrogen-bonded Turn	trans	-110.1	-9.3	178.1	30.9	0	0	0	0	115.1	E429	E429-T431 PolarHBondContact O-N 3.19Å; E429-T431 VanDerWaalsContact O-N 3.1Å
432	T	33.2	Very low	41.7	Very low	102 Å²	102	139.2 Å²	139.2	63%	0.626	67%	0.673	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99	-20.6	-179.2	13.5	0	0	0	0	114.5
433	D	33.9	Very low	40	Very low	129 Å²	129	143.5 Å²	143.5	69%	0.69	69%	0.687	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.1	-5.8	-177.2	-98.2	-5.4	0	0	0	115.6
434	K	36.1	Very low	38.5	Very low	182 Å²	182	150.6 Å²	150.6	79%	0.791	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.3	-12.4	176.5	-80.7	-170.3	175.7	-176.4	0	114.7
435	E	36.4	Very low	37.3	Very low	156 Å²	156	157 Å²	157	73%	0.729	75%	0.746	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.1	-27.8	173.8	-99.4	173.5	167	0	0	112.8	K437 R438	E435-K437 VanDerWaalsContact C-N 3.3Å; E435-K437 PolarHBondContact O-N 3.18Å; E435-R438 PolarHBondContact O-N 3.42Å
436	N	36.7	Very low	36.3	Very low	143 Å²	143	162.5 Å²	162.5	77%	0.765	77%	0.765	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.2	9.6	178.8	-91.1	-1.4	0	0	0	115.7
437	K	39.9	Very low	36	Very low	189 Å²	189	166 Å²	166	82%	0.822	78%	0.781	S	S	*	*	T	Hydrogen-bonded Turn	trans	-113.1	13.5	170	-77.7	-171.2	177.4	-178.6	0	113.7	E435	E435-K437 VanDerWaalsContact C-N 3.3Å; E435-K437 PolarHBondContact O-N 3.18Å
438	R	42.8	Very low	35.9	Very low	214 Å²	214	164.1 Å²	164.1	81%	0.808	78%	0.778	S	S	*	*			trans	-132.7	60.7	169.8	-75.7	-172.7	175.6	-170.6	-1.8	110.1	E435	E435-R438 PolarHBondContact O-N 3.42Å
439	H	39.1	Very low	36.1	Very low	256 Å²	256	164.5 Å²	164.5	100%	1.185	79%	0.786	S	S	*	*			trans	-145.5	0	151.2	-87.7	-56.2	0	0	0	109.4

Retrieved 439 of 439 residues in 895.7 ms (Link to these results)

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