A0A087XJL8_POEFO Loading...

UDP-glucuronosyltransferase

AlphaFold DB , UniProt , Accession A0A087XJL8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 529 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M51.8Low60.1Low212 Ų212121 Ų121100%1.04464%0.636SS**  0-44.20-127.8167.47500114.1L3M1-L3 PolarHBondContact O-N 3.42Å
2K53.1Low60Low195 Ų195122.1 Ų122.185%0.84864%0.641SS**Hα-helixtrans-64.2-32.6-179.7-76.2-178.2175.3179.30115.4S6K2-S6 PolarHBondContact O-N 3.33Å
3L53.1Low59.7Low143 Ų143123.2 Ų123.275%0.74965%0.647SS**Hα-helixtrans-74.1-35.9-178.3-150.181.2000113.3M1 L5 S6 V7M1-L3 PolarHBondContact O-N 3.42Å; L3-L5 VanDerWaalsContact C-N 3.34Å; L3-S6 PolarHBondContact O-N 3.24Å; L3-V7 WeakPolarHBondContact O-CG2 3.47Å; L3-V7 PolarHBondContact O-N 3.49Å
4H55Low59.4Low144 Ų144121.9 Ų121.967%0.66765%0.652SS**Hα-helixtrans-69.5-32.8177.5-72.3-54.8000112.3V7 C8H4-V7 PolarHBondContact O-N 3.41Å; H4-C8 WeakPolarHBondContact O-CB 3.37Å; H4-C8 PolarHBondContact O-N 3.44Å; H4-C8 PolarHBondContact O-SG 2.91Å; H4-C8 VanDerWaalsContact O-SG 3.33Å
5L60.1Low59Low126 Ų126116 Ų11666%0.6663%0.631SS**Hα-helixtrans-65.5-40.8176-146.679.9000111.3L3 C8 V9L3-L5 VanDerWaalsContact C-N 3.34Å; L5-C8 PolarHBondContact O-N 3Å; L5-V9 WeakPolarHBondContact O-CB 3.4Å; L5-V9 WeakPolarHBondContact O-CG2 3.2Å; L5-V9 PolarHBondContact O-N 3.41Å
6S63.4Low58.6Low71 Ų71116.4 Ų116.450%0.49764%0.639SS.*Hα-helixtrans-67-36.2176.8-67.10000113.3K2 L3 L10K2-S6 PolarHBondContact O-N 3.33Å; L3-S6 PolarHBondContact O-N 3.24Å; S6-L10 WeakPolarHBondContact O-CB 3.48Å; S6-L10 WeakPolarHBondContact O-CD1 3.5Å; S6-L10 WeakPolarHBondContact O-CG 3.5Å; S6-L10 PolarHBondContact O-N 2.87Å
7V67.9Low57.8Low76 Ų76124.1 Ų124.146%0.46166%0.656SS.*Hα-helixtrans-70.7-40.4176174.70000111.2L3 H4 L10 L11L3-V7 WeakPolarHBondContact O-CG2 3.47Å; L3-V7 PolarHBondContact O-N 3.49Å; H4-V7 PolarHBondContact O-N 3.41Å; V7-L10 PolarHBondContact O-N 3.41Å; V7-L11 HydrophobicContact CG1-CD1 3.88Å; V7-L11 WeakPolarHBondContact O-CB 3.37Å; V7-L11 WeakPolarHBondContact O-CD1 3.45Å; V7-L11 WeakPolarHBondContact O-CG 3.36Å; V7-L11 PolarHBondContact O-N 2.92Å
8C65.8Low57.2Low68 Ų68122.2 Ų122.246%0.45965%0.654SS.*Hα-helixtrans-67.1-37.3174.4-69.30000112.4H4 L5 L11 L12H4-C8 WeakPolarHBondContact O-CB 3.37Å; H4-C8 PolarHBondContact O-N 3.44Å; H4-C8 PolarHBondContact O-SG 2.91Å; H4-C8 VanDerWaalsContact O-SG 3.33Å; L5-C8 PolarHBondContact O-N 3Å; C8-L11 PolarHBondContact O-N 2.87Å; C8-L12 VanDerWaalsContact O-CB 3.3Å; C8-L12 WeakPolarHBondContact O-CB 3.33Å; C8-L12 WeakPolarHBondContact O-CD1 3.4Å; C8-L12 WeakPolarHBondContact O-CG 3.26Å; C8-L12 PolarHBondContact O-N 3.4Å
9V67.7Low57Low72 Ų72120.2 Ų120.244%0.43665%0.651SS.*Hα-helixtrans-69-38.2174.51710000111.4L5 L12 L13L5-V9 WeakPolarHBondContact O-CB 3.4Å; L5-V9 WeakPolarHBondContact O-CG2 3.2Å; L5-V9 PolarHBondContact O-N 3.41Å; V9-L12 PolarHBondContact O-N 3.37Å; V9-L13 HydrophobicContact CG1-CD1 3.86Å; V9-L13 HydrophobicContact CG1-CG 4.42Å; V9-L13 WeakPolarHBondContact O-CB 3.32Å; V9-L13 VanDerWaalsContact O-CG 3.26Å; V9-L13 WeakPolarHBondContact O-CG 3.3Å; V9-L13 PolarHBondContact O-N 2.82Å
10L62.9Low57.5Low109 Ų109122.4 Ų122.457%0.57166%0.662SS**Hα-helixtrans-65.9-39.2171.8-83.7158.8000111.9S6 V7 L13 C14S6-L10 WeakPolarHBondContact O-CB 3.48Å; S6-L10 WeakPolarHBondContact O-CD1 3.5Å; S6-L10 WeakPolarHBondContact O-CG 3.5Å; S6-L10 PolarHBondContact O-N 2.87Å; V7-L10 PolarHBondContact O-N 3.41Å; L10-L13 PolarHBondContact O-N 2.82Å; L10-C14 VanDerWaalsContact O-CB 3.31Å; L10-C14 WeakPolarHBondContact O-CB 3.49Å; L10-C14 PolarHBondContact O-N 2.83Å; L10-C14 PolarHBondContact O-SG 3.38Å
11L60.9Low58.9Low115 Ų115117.6 Ų117.660%0.60264%0.642SS**Hα-helixtrans-69-31.6173.8-78.9161.4000113V7 C8 C14 G15V7-L11 HydrophobicContact CG1-CD1 3.88Å; V7-L11 WeakPolarHBondContact O-CB 3.37Å; V7-L11 WeakPolarHBondContact O-CD1 3.45Å; V7-L11 WeakPolarHBondContact O-CG 3.36Å; V7-L11 PolarHBondContact O-N 2.92Å; C8-L11 PolarHBondContact O-N 2.87Å; L11-C14 CarbonylContact O-C 3.49Å; L11-G15 WeakPolarHBondContact O-CA 3.31Å; L11-G15 PolarHBondContact O-N 3.19Å
12L57.9Low60.9Low134 Ų134108 Ų10870%0.70260%0.596SS**Hα-helixtrans-76-31.9172.8-81158.2000112.3C8 V9 G15C8-L12 VanDerWaalsContact O-CB 3.3Å; C8-L12 WeakPolarHBondContact O-CB 3.33Å; C8-L12 WeakPolarHBondContact O-CD1 3.4Å; C8-L12 WeakPolarHBondContact O-CG 3.26Å; C8-L12 PolarHBondContact O-N 3.4Å; V9-L12 PolarHBondContact O-N 3.37Å; L12-G15 PolarHBondContact O-N 3.22Å
13L56.5Low63.1Low137 Ų137101.9 Ų101.972%0.71757%0.57SS**Hα-helixtrans-76.8-24.7171.1-73.5166.3000112.4V9 L10 G15V9-L13 HydrophobicContact CG1-CD1 3.86Å; V9-L13 HydrophobicContact CG1-CG 4.42Å; V9-L13 WeakPolarHBondContact O-CB 3.32Å; V9-L13 VanDerWaalsContact O-CG 3.26Å; V9-L13 WeakPolarHBondContact O-CG 3.3Å; V9-L13 PolarHBondContact O-N 2.82Å; L10-L13 PolarHBondContact O-N 2.82Å; L13-G15 VanDerWaalsContact C-N 3.31Å
14C56Low65.2Low105 Ų10595.1 Ų95.171%0.70953%0.534SS*.SBendtrans-82.9-11164.9-68.90000112.5L10 L11L10-C14 VanDerWaalsContact O-CB 3.31Å; L10-C14 WeakPolarHBondContact O-CB 3.49Å; L10-C14 PolarHBondContact O-N 2.83Å; L10-C14 PolarHBondContact O-SG 3.38Å; L11-C14 CarbonylContact O-C 3.49Å
15G53.7Low67.3Low33 Ų3388.2 Ų88.234%0.3450%0.503SS..THydrogen-bonded Turntrans-79.4117.3176.700000110.4L11 L12 L13L11-G15 WeakPolarHBondContact O-CA 3.31Å; L11-G15 PolarHBondContact O-N 3.19Å; L12-G15 PolarHBondContact O-N 3.22Å; L13-G15 VanDerWaalsContact C-N 3.31Å
16T52.1Low69.1Low123 Ų12382.2 Ų82.276%0.75547%0.471SS*.THydrogen-bonded Turntrans66.760.9172.977.60000116.3S18T16-S18 PolarHBondContact O-N 3.12Å; T16-S18 VanDerWaalsContact O-N 3.12Å
17R44.5Very low70.8Confident246 Ų24678.9 Ų78.993%0.92845%0.447SS*.  -68.689.3119.2-85.8-170.6-179-177.91.5104.5S19R17-S19 PolarHBondContact O-N 2.83Å
18S47.4Very low72.1Confident90 Ų9075.2 Ų75.263%0.62943%0.426SS*.  trans-51.6104.2159.7-65.50000104.3T16 N20T16-S18 PolarHBondContact O-N 3.12Å; T16-S18 VanDerWaalsContact O-N 3.12Å; S18-N20 PolarHBondContact O-N 2.81Å
19S52.8Low73.4Confident85 Ų8572 Ų7259%0.59440%0.404SS*.  trans-62.7102.8169.160.10000103.3R17 G21R17-S19 PolarHBondContact O-N 2.83Å; S19-G21 PolarHBondContact O-N 3.07Å
20N67.4Low74.5Confident164 Ų16469.4 Ų69.488%0.87739%0.387SS*.  trans-75.363.5178.6-142.328.3000106.8S18 G22S18-N20 PolarHBondContact O-N 2.81Å; N20-G22 PolarHBondContact O-N 2.93Å
21G86.2Confident75.7Confident22 Ų2264.2 Ų64.223%0.22736%0.36CS..PPolyproline II helixtrans-74.4117.4-177.100000108.2S19 G48S19-G21 PolarHBondContact O-N 3.07Å; G21-G48 WeakPolarHBondContact CA-O 3.5Å
22G95.4Very high77Confident9 Ų960.6 Ų60.69%0.09334%0.344CS..PPolyproline II helixtrans-63.6157.5171.900000112.9N20 H49 Q50 D145N20-G22 PolarHBondContact O-N 2.93Å; G22-H49 PolarHBondContact N-ND1 3.22Å; G22-H49 WeakPolarHBondContact O-CA 3.46Å; G22-H49 WeakPolarHBondContact O-CB 3.47Å; G22-H49 PolarHBondContact O-ND1 3.49Å; G22-Q50 PolarHBondContact O-N 3.06Å; G22-Q50 VanDerWaalsContact O-N 3.07Å; G22-D145 WeakPolarHBondContact CA-OD2 2.92Å
23K97.6Very high78.7Confident68 Ų6856.5 Ų56.530%0.29632%0.321SS..EExtended strand (participates in β ladder)trans-94120.8173.3-70.5176.4170.2-174.40109.8Q50 G142 N143 Y144 D145K23-Q50 CarbonylContact C-O 3.54Å; K23-Q50 WeakPolarHBondContact CA-O 3.49Å; K23-Q50 HydrophobicContact CG-CB 4.16Å; K23-G142 WeakPolarHBondContact CD-O 3.21Å; K23-G142 PolarHBondContact NZ-O 2.99Å; K23-N143 WeakPolarHBondContact CD-O 3.4Å; K23-Y144 HydrophobicContact CB-CD1 4.05Å; K23-D145 PolarHBondContact N-OD2 3.28Å; K23-D145 PolarHBondContact O-N 3.33Å
24I98.6Very high80.4Confident0 Ų050.1 Ų50.10%029%0.288CS..EExtended strand (participates in β ladder)trans-114.4119.9-171.7-56.9174.7000108.2V26 L44 H49 Q50 V51 T52 V146 F148 I463 M467I24-V26 HydrophobicContact CG2-CG2 4.1Å; I24-L44 HydrophobicContact CD1-CB 4.15Å; I24-L44 HydrophobicContact CD1-CD1 3.72Å; I24-L44 HydrophobicContact CD1-CD2 3.63Å; I24-L44 HydrophobicContact CD1-CG 4.04Å; I24-H49 HydrophobicContact CD1-CB 3.81Å; I24-H49 HydrophobicContact CG1-CB 4.5Å; I24-Q50 PolarHBondContact N-O 2.91Å; I24-V51 HydrophobicContact CB-CG2 4.39Å; I24-V51 HydrophobicContact CD1-CG2 4.43Å; I24-T52 PolarHBondContact O-N 3.07Å; I24-V146 HydrophobicContact CB-CG1 4.34Å; I24-V146 HydrophobicContact CG1-CG1 3.91Å; I24-V146 HydrophobicContact CG2-CG1 4.1Å; I24-F148 HydrophobicContact CG2-CB 4.19Å; I24-I463 HydrophobicContact CD1-CG2 4.18Å; I24-M467 HydrophobicContact CD1-CE 4.14Å; I24-M467 HydrophobicContact CD1-SD 4.23Å; I24-M467 HydrophobicContact CG1-CE 4.46Å; I24-M467 HydrophobicContact CG1-SD 3.9Å
25L98.7Very high82Confident0 Ų048.6 Ų48.60%027%0.272CS..EExtended strand (participates in β ladder)trans-89.7127.8169.6-178.959.5000108.9L54 L139 Y144 V146 L147 F148 L163L25-L54 HydrophobicContact CD1-CD2 4.29Å; L25-L54 HydrophobicContact CD1-CG 4.08Å; L25-L139 HydrophobicContact CD1-CD2 3.95Å; L25-L139 HydrophobicContact CD2-CD2 4.16Å; L25-Y144 HydrophobicContact CB-CD1 3.72Å; L25-Y144 HydrophobicContact CB-CD2 3.98Å; L25-Y144 HydrophobicContact CB-CE1 4.05Å; L25-Y144 HydrophobicContact CB-CE2 4.28Å; L25-Y144 HydrophobicContact CB-CG 3.68Å; L25-Y144 HydrophobicContact CD1-CE1 4.32Å; L25-Y144 HydrophobicContact CD1-CE2 4.11Å; L25-Y144 HydrophobicContact CD2-CD2 4.08Å; L25-Y144 HydrophobicContact CD2-CE2 4.19Å; L25-Y144 HydrophobicContact CG-CD2 4.45Å; L25-Y144 HydrophobicContact CG-CE2 4.43Å; L25-V146 PolarHBondContact N-O 3.36Å; L25-L147 HydrophobicContact CD2-CD1 3.99Å; L25-L147 HydrophobicContact CD2-CG 4.46Å; L25-L147 HydrophobicContact CG-CD1 4.46Å; L25-L147 HydrophobicContact CG-CG 4.45Å; L25-L147 CarbonylContact O-C 3.56Å; L25-L147 WeakPolarHBondContact O-CA 3.15Å; L25-F148 PolarHBondContact O-N 3.42Å; L25-L163 HydrophobicContact CD2-CD1 3.72Å
26V98.4Very high83.8Confident0 Ų047.2 Ų47.20%026%0.257CS..EExtended strand (participates in β ladder)trans-111.7123.9179.4-1740000109.6I24 M37 L41 V51 T52 V53 L54 F148I24-V26 HydrophobicContact CG2-CG2 4.1Å; V26-M37 HydrophobicContact CG1-CE 3.53Å; V26-L41 HydrophobicContact CG1-CD1 4.18Å; V26-L41 HydrophobicContact CG1-CD2 4.3Å; V26-L41 HydrophobicContact CG2-CD1 4.25Å; V26-L41 HydrophobicContact CG2-CD2 3.61Å; V26-V51 HydrophobicContact CG2-CG1 3.68Å; V26-T52 PolarHBondContact N-O 3.24Å; V26-V53 HydrophobicContact CB-CB 4.29Å; V26-V53 HydrophobicContact CB-CG1 4.23Å; V26-V53 HydrophobicContact CB-CG2 3.96Å; V26-V53 HydrophobicContact CG1-CG1 4.26Å; V26-V53 HydrophobicContact CG1-CG2 4.45Å; V26-V53 HydrophobicContact CG2-CG2 4.14Å; V26-L54 PolarHBondContact O-N 2.92Å; V26-F148 VanDerWaalsContact CA-O 3.29Å; V26-F148 WeakPolarHBondContact CA-O 3.47Å
27W97.9Very high85.7Confident0 Ų041.4 Ų41.40%022%0.221CC..  trans-69.8143.4174.6-158.9-110.3000110.8L54 L126 V129 L147 F148 A149 P154 G155 T159W27-L54 HydrophobicContact CD2-CD1 4.47Å; W27-L54 HydrophobicContact CE3-CD1 3.62Å; W27-L54 HydrophobicContact CH2-CD1 4.5Å; W27-L54 HydrophobicContact CZ3-CD1 3.63Å; W27-L126 HydrophobicContact CH2-CD1 4.08Å; W27-L126 HydrophobicContact CZ2-CD1 3.98Å; W27-V129 HydrophobicContact CH2-CB 4.07Å; W27-V129 HydrophobicContact CH2-CG1 3.82Å; W27-V129 HydrophobicContact CH2-CG2 4.18Å; W27-V129 HydrophobicContact CZ3-CG1 3.95Å; W27-L147 HydrophobicContact CB-CD2 4.29Å; W27-F148 PolarHBondContact N-O 3.4Å; W27-A149 HydrophobicContact CB-CB 3.57Å; W27-A149 HydrophobicContact CG-CB 4.35Å; W27-P154 WeakPolarHBondContact CZ2-O 3.44Å; W27-P154 PolarHBondContact NE1-O 2.92Å; W27-G155 VanDerWaalsContact CZ2-C 3.44Å; W27-T159 VanDerWaalsContact CH2-OG1 3.25Å; W27-T159 WeakPolarHBondContact CH2-OG1 3.46Å; W27-T159 HydrophobicContact CZ3-CG2 3.93Å; W27-T159 VanDerWaalsContact CZ3-OG1 3.24Å; W27-T159 WeakPolarHBondContact CZ3-OG1 3.08Å
28Y95Very high88Confident0 Ų031.9 Ų31.90%019%0.186CC..  trans-67154-17966.7-87.9000111.5L54 P56 F75 F125 V129 Y153Y28-L54 WeakPolarHBondContact CB-O 3.29Å; Y28-L54 HydrophobicContact CD1-CB 4.34Å; Y28-P56 HydrophobicContact CD2-CG 4.1Å; Y28-P56 HydrophobicContact CG-CG 4.45Å; Y28-F75 AromaticContact CD1-CE1 3.59Å; Y28-F75 HydrophobicContact CD1-CE1 3.59Å; Y28-F75 AromaticContact CD1-CZ 3.46Å; Y28-F75 HydrophobicContact CD1-CZ 3.46Å; Y28-F75 VanDerWaalsContact CD1-CZ 3.46Å; Y28-F75 HydrophobicContact CD2-CZ 4.42Å; Y28-F75 HydrophobicContact CE1-CE1 4.13Å; Y28-F75 HydrophobicContact CE1-CE2 4.46Å; Y28-F75 AromaticContact CE1-CZ 3.55Å; Y28-F75 HydrophobicContact CE1-CZ 3.55Å; Y28-F75 HydrophobicContact CE2-CZ 4.5Å; Y28-F75 HydrophobicContact CG-CE1 4.02Å; Y28-F75 AromaticContact CG-CZ 3.95Å; Y28-F75 HydrophobicContact CG-CZ 3.95Å; Y28-F125 HydrophobicContact CD2-CD1 4.31Å; Y28-F125 HydrophobicContact CE2-CB 4.34Å; Y28-F125 AromaticContact CE2-CD1 3.61Å; Y28-F125 HydrophobicContact CE2-CD1 3.61Å; Y28-F125 HydrophobicContact CE2-CE1 4.42Å; Y28-F125 HydrophobicContact CE2-CG 4.44Å; Y28-F125 VanDerWaalsContact OH-CB 3.3Å; Y28-F125 WeakPolarHBondContact OH-CB 3.09Å; Y28-V129 HydrophobicContact CE1-CG2 4.44Å; Y28-Y153 AromaticContact CD2-CD2 3.85Å; Y28-Y153 HydrophobicContact CD2-CD2 3.85Å; Y28-Y153 HydrophobicContact CD2-CE2 4.42Å; Y28-Y153 HydrophobicContact CD2-CG 4.4Å; Y28-Y153 HydrophobicContact CE2-CD1 4.43Å; Y28-Y153 AromaticContact CE2-CD2 3.56Å; Y28-Y153 HydrophobicContact CE2-CD2 3.56Å; Y28-Y153 HydrophobicContact CE2-CE2 4.29Å; Y28-Y153 AromaticContact CE2-CG 3.66Å; Y28-Y153 HydrophobicContact CE2-CG 3.66Å
29T94Very high90.2Very high1 Ų128.4 Ų28.41%0.00616%0.162CC..  trans-158.6179.9177.4-170.20000109.5H33 W34 M37 M62 I152T29-H33 HydrophobicContact CG2-CB 4.11Å; T29-H33 WeakPolarHBondContact OG1-CB 3.35Å; T29-W34 HydrophobicContact CG2-CB 3.92Å; T29-W34 HydrophobicContact CG2-CE3 4.14Å; T29-M37 HydrophobicContact CG2-SD 3.81Å; T29-M62 WeakPolarHBondContact O-CG 3.28Å; T29-I152 WeakPolarHBondContact OG1-CG2 3.38Å
30E89.9Confident92.3Very high16 Ų1624.4 Ų24.48%0.07513%0.134CC..  trans-132.6163.7-174.9-72.5-67.417300112.8S32 H33 W34 S59 M60 F61 Y153E30-S32 PolarHBondContact O-N 3.39Å; E30-H33 WeakPolarHBondContact O-CB 3.23Å; E30-H33 PolarHBondContact O-N 2.74Å; E30-H33 VanDerWaalsContact O-N 3.13Å; E30-W34 PolarHBondContact O-N 2.79Å; E30-S59 VanDerWaalsContact CD-OG 3.27Å; E30-S59 WeakPolarHBondContact OE1-CA 3.38Å; E30-S59 VanDerWaalsContact OE1-CB 3.26Å; E30-S59 WeakPolarHBondContact OE1-CB 3.27Å; E30-S59 PolarHBondContact OE1-OG 2.81Å; E30-S59 PolarHBondContact OE2-OG 3.22Å; E30-M60 PolarHBondContact OE1-N 2.79Å; E30-M60 PolarHBondContact OE2-N 3.39Å; E30-F61 HydrophobicContact CB-CD2 4.23Å; E30-F61 VanDerWaalsContact OE2-CB 3.31Å; E30-F61 WeakPolarHBondContact OE2-CB 3.45Å; E30-F61 VanDerWaalsContact OE2-CD2 3.32Å; E30-F61 WeakPolarHBondContact OE2-CD2 3.41Å; E30-F61 PolarHBondContact OE2-N 2.88Å; E30-Y153 HydrophobicContact CB-CE2 4.27Å; E30-Y153 HydrophobicContact CG-CE2 3.88Å
31A88.7Confident93.7Very high1 Ų116.6 Ų16.61%0.0089%0.092CC..Hα-helixtrans47.5-122.8168.600000115H33 W34 I35 F61 M311A31-H33 VanDerWaalsContact C-N 3.3Å; A31-H33 PolarHBondContact O-N 2.74Å; A31-W34 PolarHBondContact O-N 3.01Å; A31-I35 WeakPolarHBondContact O-CG1 3.43Å; A31-I35 PolarHBondContact O-N 3.28Å; A31-I35 VanDerWaalsContact O-N 3.09Å; A31-F61 HydrophobicContact CB-CD1 4.05Å; A31-F61 HydrophobicContact CB-CD2 3.68Å; A31-F61 HydrophobicContact CB-CE1 4.11Å; A31-F61 HydrophobicContact CB-CE2 3.76Å; A31-F61 HydrophobicContact CB-CG 3.84Å; A31-F61 HydrophobicContact CB-CZ 3.97Å; A31-M311 HydrophobicContact CB-CE 3.23Å; A31-M311 HydrophobicContact CB-CG 4.49Å
32S87.9Confident94.1Very high39 Ų3919.3 Ų19.327%0.27310%0.099SC..Hα-helixtrans-67.9-26.9-175.854.30000113.4E30 N36 N377E30-S32 PolarHBondContact O-N 3.39Å; S32-N36 VanDerWaalsContact O-CB 3.28Å; S32-N36 WeakPolarHBondContact O-CB 3.1Å; S32-N36 PolarHBondContact O-N 2.73Å; S32-N377 PolarHBondContact O-ND2 3.29Å
33H92.9Very high94.1Very high48 Ų4819.6 Ų19.622%0.22210%0.098CC..Hα-helixtrans-68.1-44.4175.4-65.8-118.8000109.5T29 E30 A31 N36 M37 D150 R258T29-H33 HydrophobicContact CG2-CB 4.11Å; T29-H33 WeakPolarHBondContact OG1-CB 3.35Å; E30-H33 WeakPolarHBondContact O-CB 3.23Å; E30-H33 PolarHBondContact O-N 2.74Å; E30-H33 VanDerWaalsContact O-N 3.13Å; A31-H33 VanDerWaalsContact C-N 3.3Å; A31-H33 PolarHBondContact O-N 2.74Å; H33-N36 PolarHBondContact O-N 2.61Å; H33-M37 WeakPolarHBondContact O-CG 3.42Å; H33-M37 PolarHBondContact O-N 3.47Å; H33-D150 IonicContact CE1-OD1 2.75Å; H33-D150 IonicContact CE1-OD2 2.91Å; H33-D150 IonicContact CG-OD1 3.58Å; H33-D150 IonicContact CG-OD2 3.91Å; H33-D150 IonicContact ND1-OD1 2.79Å; H33-D150 PolarHBondContact ND1-OD1 3.17Å; H33-D150 IonicContact ND1-OD2 3.65Å; H33-D150 PolarHBondContact ND1-OD2 3.33Å; H33-R258 PolarHBondContact ND1-NH2 3.04Å
34W92.8Very high94Very high3 Ų316.3 Ų16.31%0.0118%0.084CC..Hα-helixtrans-61.8-47.7174.7-180-136000112.6T29 E30 A31 N36 M37 K38 L41 V53 M62 F70 Y72T29-W34 HydrophobicContact CG2-CB 3.92Å; T29-W34 HydrophobicContact CG2-CE3 4.14Å; E30-W34 PolarHBondContact O-N 2.79Å; A31-W34 PolarHBondContact O-N 3.01Å; W34-N36 PolarHBondContact O-N 3.02Å; W34-M37 PolarHBondContact O-N 2.87Å; W34-K38 HydrophobicContact CD2-CG 4.17Å; W34-K38 HydrophobicContact CH2-CG 4.14Å; W34-K38 HydrophobicContact CZ2-CD 4.26Å; W34-K38 VanDerWaalsContact CZ2-CE 3.48Å; W34-K38 HydrophobicContact CZ2-CG 3.8Å; W34-K38 PolarHBondContact O-N 3.12Å; W34-K38 VanDerWaalsContact O-N 3.11Å; W34-L41 HydrophobicContact CH2-CD1 3.84Å; W34-L41 HydrophobicContact CZ3-CD1 3.7Å; W34-V53 HydrophobicContact CH2-CB 4.43Å; W34-V53 HydrophobicContact CH2-CG1 3.72Å; W34-V53 HydrophobicContact CH2-CG2 4.15Å; W34-V53 HydrophobicContact CZ3-CG1 3.75Å; W34-M62 HydrophobicContact CD2-CE 3.79Å; W34-M62 HydrophobicContact CD2-CG 4.16Å; W34-M62 HydrophobicContact CE3-CE 3.78Å; W34-M62 HydrophobicContact CG-CG 3.95Å; W34-M62 HydrophobicContact CH2-CE 3.86Å; W34-M62 HydrophobicContact CZ2-CE 3.82Å; W34-M62 HydrophobicContact CZ3-CE 3.82Å; W34-F70 AromaticContact CH2-CE2 3.6Å; W34-F70 HydrophobicContact CH2-CE2 3.6Å; W34-F70 AromaticContact CH2-CZ 3.57Å; W34-F70 HydrophobicContact CH2-CZ 3.57Å; W34-F70 AromaticContact CZ2-CE2 3.88Å; W34-F70 HydrophobicContact CZ2-CE2 3.88Å; W34-F70 AromaticContact CZ2-CZ 3.73Å; W34-F70 HydrophobicContact CZ2-CZ 3.73Å; W34-Y72 HydrophobicContact CH2-CE1 4.12Å; W34-Y72 AromaticContact CZ2-CE1 3.76Å; W34-Y72 HydrophobicContact CZ2-CE1 3.76Å; W34-Y72 WeakPolarHBondContact CZ2-OH 3.43Å
35I89.6Confident93.9Very high73 Ų7317.7 Ų17.737%0.3749%0.092SC..Hα-helixtrans-57.4-36.4177-67.7167.3000111.3A31 P39A31-I35 WeakPolarHBondContact O-CG1 3.43Å; A31-I35 PolarHBondContact O-N 3.28Å; A31-I35 VanDerWaalsContact O-N 3.09Å; I35-P39 WeakPolarHBondContact O-CD 3.44Å
36N91.3Very high93.8Very high4 Ų422.4 Ų22.42%0.02112%0.118CC..Hα-helixtrans-75.3-34.4-178.8-176.5-89.2000112.9S32 H33 W34 P39 R258 I279 H280 N377S32-N36 VanDerWaalsContact O-CB 3.28Å; S32-N36 WeakPolarHBondContact O-CB 3.1Å; S32-N36 PolarHBondContact O-N 2.73Å; H33-N36 PolarHBondContact O-N 2.61Å; W34-N36 PolarHBondContact O-N 3.02Å; N36-P39 WeakPolarHBondContact O-CD 3.47Å; N36-R258 WeakPolarHBondContact OD1-CD 3.24Å; N36-I279 WeakPolarHBondContact ND2-CG1 3.16Å; N36-I279 WeakPolarHBondContact OD1-CD1 3.48Å; N36-I279 WeakPolarHBondContact OD1-CG1 3.3Å; N36-H280 PolarHBondContact ND2-ND1 3.02Å; N36-N377 PolarHBondContact ND2-OD1 3.33Å
37M93.4Very high93.6Very high0 Ų026.8 Ų26.80%013%0.134CC..Hα-helixtrans-73.4-37.5177.1-69.9-178.179.200112.9V26 T29 H33 W34 V40 L41 F148 D150V26-M37 HydrophobicContact CG1-CE 3.53Å; T29-M37 HydrophobicContact CG2-SD 3.81Å; H33-M37 WeakPolarHBondContact O-CG 3.42Å; H33-M37 PolarHBondContact O-N 3.47Å; W34-M37 PolarHBondContact O-N 2.87Å; M37-V40 WeakPolarHBondContact O-CB 3.49Å; M37-V40 PolarHBondContact O-N 3.08Å; M37-L41 WeakPolarHBondContact O-CG 3.27Å; M37-L41 PolarHBondContact O-N 3.25Å; M37-L41 VanDerWaalsContact O-N 3.15Å; M37-F148 HydrophobicContact CE-CD1 3.44Å; M37-F148 VanDerWaalsContact CE-CD1 3.44Å; M37-F148 HydrophobicContact CE-CE1 3.31Å; M37-F148 HydrophobicContact CE-CG 4.14Å; M37-F148 HydrophobicContact CE-CZ 3.91Å; M37-F148 HydrophobicContact CG-CE1 4.38Å; M37-D150 HydrophobicContact SD-CB 3.68Å
38K92.6Very high93.4Very high47 Ų4728.3 Ų28.320%0.20415%0.15CC..Hα-helixtrans-46-49.7-175.9-80.8-170-176.8-169.20114.2W34 V40 L41 E42 E66 F70W34-K38 HydrophobicContact CD2-CG 4.17Å; W34-K38 HydrophobicContact CH2-CG 4.14Å; W34-K38 HydrophobicContact CZ2-CD 4.26Å; W34-K38 VanDerWaalsContact CZ2-CE 3.48Å; W34-K38 HydrophobicContact CZ2-CG 3.8Å; W34-K38 PolarHBondContact O-N 3.12Å; W34-K38 VanDerWaalsContact O-N 3.11Å; K38-V40 VanDerWaalsContact C-N 3.28Å; K38-V40 PolarHBondContact O-N 3.32Å; K38-L41 PolarHBondContact O-N 3.28Å; K38-L41 VanDerWaalsContact O-N 3.12Å; K38-E42 WeakPolarHBondContact O-CG 3.37Å; K38-E42 PolarHBondContact O-N 2.91Å; K38-E66 IonicContact NZ-OE2 3.27Å; K38-F70 HydrophobicContact CG-CZ 4.47Å
39P93.1Very high93.5Very high17 Ų1729.3 Ų29.311%0.1115%0.154CC..Hα-helixtrans-58.7-34.5179-2735.2000114.7I35 N36 T43 H280I35-P39 WeakPolarHBondContact O-CD 3.44Å; N36-P39 WeakPolarHBondContact O-CD 3.47Å; P39-T43 PolarHBondContact O-N 3.35Å; P39-T43 PolarHBondContact O-OG1 2.81Å; P39-H280 HydrophobicContact CG-CB 4.32Å
40V96.4Very high93.7Very high1 Ų134.9 Ų34.91%0.00618%0.181CC..Hα-helixtrans-69.6-45.3176.3-179.30000109.6M37 K38 T43 L44 F148 I279 A459 V460 I463M37-V40 WeakPolarHBondContact O-CB 3.49Å; M37-V40 PolarHBondContact O-N 3.08Å; K38-V40 VanDerWaalsContact C-N 3.28Å; K38-V40 PolarHBondContact O-N 3.32Å; V40-T43 PolarHBondContact O-N 3.3Å; V40-L44 HydrophobicContact CG1-CD1 4.14Å; V40-L44 WeakPolarHBondContact O-CG 3.48Å; V40-L44 PolarHBondContact O-N 3.22Å; V40-F148 HydrophobicContact CG1-CE1 4.2Å; V40-F148 HydrophobicContact CG1-CZ 4.4Å; V40-I279 HydrophobicContact CG2-CB 4.44Å; V40-I279 HydrophobicContact CG2-CD1 3.9Å; V40-A459 HydrophobicContact CG1-CB 4.38Å; V40-A459 HydrophobicContact CG2-CB 4.28Å; V40-V460 HydrophobicContact CG1-CG2 3.98Å; V40-I463 HydrophobicContact CG1-CD1 3.79Å
41L96.7Very high94.1Very high0 Ų034.4 Ų34.40%018%0.179CC..Hα-helixtrans-61.8-44.6178.1-55.6-172.9000112.2V26 W34 M37 K38 T43 L44 V45 V51 V53 F70 F148V26-L41 HydrophobicContact CG1-CD1 4.18Å; V26-L41 HydrophobicContact CG1-CD2 4.3Å; V26-L41 HydrophobicContact CG2-CD1 4.25Å; V26-L41 HydrophobicContact CG2-CD2 3.61Å; W34-L41 HydrophobicContact CH2-CD1 3.84Å; W34-L41 HydrophobicContact CZ3-CD1 3.7Å; M37-L41 WeakPolarHBondContact O-CG 3.27Å; M37-L41 PolarHBondContact O-N 3.25Å; M37-L41 VanDerWaalsContact O-N 3.15Å; K38-L41 PolarHBondContact O-N 3.28Å; K38-L41 VanDerWaalsContact O-N 3.12Å; L41-T43 VanDerWaalsContact C-N 3.26Å; L41-T43 PolarHBondContact O-N 2.9Å; L41-L44 HydrophobicContact CD2-CD1 4.32Å; L41-L44 WeakPolarHBondContact O-CB 3.31Å; L41-L44 PolarHBondContact O-N 3.03Å; L41-V45 WeakPolarHBondContact O-CG2 3.39Å; L41-V45 PolarHBondContact O-N 2.95Å; L41-V51 HydrophobicContact CB-CG1 4.34Å; L41-V51 HydrophobicContact CD1-CG1 4.37Å; L41-V51 HydrophobicContact CD2-CG1 4.12Å; L41-V51 HydrophobicContact CG-CG1 4.5Å; L41-V53 HydrophobicContact CD1-CG2 3.85Å; L41-F70 HydrophobicContact CB-CD1 4.1Å; L41-F70 HydrophobicContact CB-CE1 4.12Å; L41-F70 HydrophobicContact CD1-CE1 4.38Å; L41-F70 HydrophobicContact CD1-CZ 4.39Å; L41-F148 HydrophobicContact CD2-CD1 3.83Å; L41-F148 HydrophobicContact CD2-CE1 4.05Å
42E94.6Very high94.5Very high79 Ų7934.9 Ų34.937%0.36918%0.182SC..Hα-helixtrans-58.5-40.6175.6-72.7172.6174.200111.5K38 V45 D46K38-E42 WeakPolarHBondContact O-CG 3.37Å; K38-E42 PolarHBondContact O-N 2.91Å; E42-V45 PolarHBondContact O-N 2.89Å; E42-D46 PolarHBondContact O-N 3.3Å
43T95.3Very high94.9Very high14 Ų1433 Ų339%0.08617%0.169CC..Hα-helixtrans-71.2-35.3178.8-53.80000111.9P39 V40 L41 V45 D46 R47 R456 V460P39-T43 PolarHBondContact O-N 3.35Å; P39-T43 PolarHBondContact O-OG1 2.81Å; V40-T43 PolarHBondContact O-N 3.3Å; L41-T43 VanDerWaalsContact C-N 3.26Å; L41-T43 PolarHBondContact O-N 2.9Å; T43-V45 VanDerWaalsContact C-N 3.33Å; T43-D46 WeakPolarHBondContact O-CB 3.27Å; T43-D46 PolarHBondContact O-N 3.01Å; T43-R47 WeakPolarHBondContact O-CG 3.45Å; T43-R47 PolarHBondContact O-N 3.36Å; T43-R456 WeakPolarHBondContact OG1-CD 3.49Å; T43-V460 HydrophobicContact CG2-CG2 3.84Å
44L97.3Very high95.2Very high0 Ų030.8 Ų30.80%016%0.158CC..Hα-helixtrans-62.3-42.8171.9-72.9161.3000110.8I24 V40 L41 R47 G48 H49 V51 V460 I463I24-L44 HydrophobicContact CD1-CB 4.15Å; I24-L44 HydrophobicContact CD1-CD1 3.72Å; I24-L44 HydrophobicContact CD1-CD2 3.63Å; I24-L44 HydrophobicContact CD1-CG 4.04Å; V40-L44 HydrophobicContact CG1-CD1 4.14Å; V40-L44 WeakPolarHBondContact O-CG 3.48Å; V40-L44 PolarHBondContact O-N 3.22Å; L41-L44 HydrophobicContact CD2-CD1 4.32Å; L41-L44 WeakPolarHBondContact O-CB 3.31Å; L41-L44 PolarHBondContact O-N 3.03Å; L44-R47 CarbonylContact O-C 3.56Å; L44-R47 PolarHBondContact O-N 3.32Å; L44-R47 VanDerWaalsContact O-N 3.16Å; L44-G48 PolarHBondContact O-N 3.2Å; L44-H49 HydrophobicContact CB-CB 4.18Å; L44-H49 VanDerWaalsContact O-CB 3.31Å; L44-H49 WeakPolarHBondContact O-CB 3.45Å; L44-H49 PolarHBondContact O-CD2 3.05Å; L44-H49 VanDerWaalsContact O-CD2 3.24Å; L44-H49 PolarHBondContact O-N 3.16Å; L44-V51 HydrophobicContact CB-CG2 4.07Å; L44-V460 HydrophobicContact CD2-CG1 3.73Å; L44-V460 HydrophobicContact CD2-CG2 4.49Å; L44-V460 HydrophobicContact CG-CG1 4.3Å; L44-V460 HydrophobicContact CG-CG2 4.28Å; L44-I463 HydrophobicContact CD1-CD1 4.06Å; L44-I463 HydrophobicContact CD1-CG2 4.42Å; L44-I463 HydrophobicContact CD2-CG2 4.08Å
45V96.5Very high95.3Very high28 Ų2830.8 Ų30.817%0.1716%0.159CC..Hα-helixtrans-62.9-42.6173.5174.60000111.4L41 E42 T43 R47 G48 V51 R69 F70L41-V45 WeakPolarHBondContact O-CG2 3.39Å; L41-V45 PolarHBondContact O-N 2.95Å; E42-V45 PolarHBondContact O-N 2.89Å; T43-V45 VanDerWaalsContact C-N 3.33Å; V45-R47 PolarHBondContact O-N 3.12Å; V45-G48 PolarHBondContact O-N 3.24Å; V45-V51 HydrophobicContact CG2-CB 4.2Å; V45-V51 HydrophobicContact CG2-CG2 3.88Å; V45-R69 HydrophobicContact CG1-CB 4.11Å; V45-R69 WeakPolarHBondContact CG1-O 3.31Å; V45-F70 HydrophobicContact CG2-CB 4.14Å
46D94.6Very high95.5Very high100 Ų10027.5 Ų27.554%0.53514%0.142SC..Hα-helixtrans-57.9-30.4174.5-76-37.7000112.8E42 T43 G48 R69E42-D46 PolarHBondContact O-N 3.3Å; T43-D46 WeakPolarHBondContact O-CB 3.27Å; T43-D46 PolarHBondContact O-N 3.01Å; D46-G48 VanDerWaalsContact C-N 3.31Å; D46-R69 VanDerWaalsContact CG-NH1 3.3Å; D46-R69 IonicContact OD1-CZ 3.97Å; D46-R69 IonicContact OD1-NH1 3.76Å; D46-R69 PolarHBondContact OD1-NH1 3.41Å; D46-R69 IonicContact OD1-NH2 3.36Å; D46-R69 PolarHBondContact OD1-NH2 2.97Å; D46-R69 IonicContact OD2-NH1 3.1Å; D46-R69 PolarHBondContact OD2-NH1 2.88Å
47R94.9Very high95.6Very high92 Ų9230.5 Ų30.535%0.34716%0.163SC..THydrogen-bonded Turntrans-897.1176.6-66-173.2-174.2-172.71.3113.9T43 L44 V45 D457 E464T43-R47 WeakPolarHBondContact O-CG 3.45Å; T43-R47 PolarHBondContact O-N 3.36Å; L44-R47 CarbonylContact O-C 3.56Å; L44-R47 PolarHBondContact O-N 3.32Å; L44-R47 VanDerWaalsContact O-N 3.16Å; V45-R47 PolarHBondContact O-N 3.12Å; R47-D457 IonicContact CZ-OD1 2.66Å; R47-D457 IonicContact NH2-OD1 3.83Å; R47-D457 PolarHBondContact NH2-OD1 3.32Å; R47-E464 WeakPolarHBondContact CD-OE1 3.44Å; R47-E464 IonicContact CZ-OE1 3.96Å; R47-E464 IonicContact NE-OE1 3.79Å; R47-E464 IonicContact NH1-OE1 3.86Å; R47-E464 PolarHBondContact NH1-OE1 3.47Å; R47-E464 IonicContact NH1-OE2 3.04Å
48G94.8Very high95.5Very high32 Ų3230.6 Ų30.633%0.3316%0.164SC..THydrogen-bonded Turntrans89.311.2173.100000115.1G21 L44 V45 D46G21-G48 WeakPolarHBondContact CA-O 3.5Å; L44-G48 PolarHBondContact O-N 3.2Å; V45-G48 PolarHBondContact O-N 3.24Å; D46-G48 VanDerWaalsContact C-N 3.31Å
49H97.1Very high95.4Very high20 Ų2029.3 Ų29.39%0.09316%0.161CC..  trans-77.2147.2175.8-63.3-71.1000112.3G22 I24 L44 E464 M467G22-H49 PolarHBondContact N-ND1 3.22Å; G22-H49 WeakPolarHBondContact O-CA 3.46Å; G22-H49 WeakPolarHBondContact O-CB 3.47Å; G22-H49 PolarHBondContact O-ND1 3.49Å; I24-H49 HydrophobicContact CD1-CB 3.81Å; I24-H49 HydrophobicContact CG1-CB 4.5Å; L44-H49 HydrophobicContact CB-CB 4.18Å; L44-H49 VanDerWaalsContact O-CB 3.31Å; L44-H49 WeakPolarHBondContact O-CB 3.45Å; L44-H49 PolarHBondContact O-CD2 3.05Å; L44-H49 VanDerWaalsContact O-CD2 3.24Å; L44-H49 PolarHBondContact O-N 3.16Å; H49-E464 IonicContact NE2-OE1 3.8Å; H49-M467 WeakPolarHBondContact CE1-CE 3.14Å
50Q97Very high95.1Very high119 Ų11930.8 Ų30.856%0.55617%0.167SC*.EExtended strand (participates in β ladder)trans-89120.7169.3-66.7177.823.600108.4G22 K23 I24G22-Q50 PolarHBondContact O-N 3.06Å; G22-Q50 VanDerWaalsContact O-N 3.07Å; K23-Q50 CarbonylContact C-O 3.54Å; K23-Q50 WeakPolarHBondContact CA-O 3.49Å; K23-Q50 HydrophobicContact CG-CB 4.16Å; I24-Q50 PolarHBondContact N-O 2.91Å
51V97.9Very high94.6Very high6 Ų633.9 Ų33.94%0.03618%0.181CC..EExtended strand (participates in β ladder)trans-114.3122.5-178.11780000108.9I24 V26 L41 L44 V45 V53 F70 Q71I24-V51 HydrophobicContact CB-CG2 4.39Å; I24-V51 HydrophobicContact CD1-CG2 4.43Å; V26-V51 HydrophobicContact CG2-CG1 3.68Å; L41-V51 HydrophobicContact CB-CG1 4.34Å; L41-V51 HydrophobicContact CD1-CG1 4.37Å; L41-V51 HydrophobicContact CD2-CG1 4.12Å; L41-V51 HydrophobicContact CG-CG1 4.5Å; L44-V51 HydrophobicContact CB-CG2 4.07Å; V45-V51 HydrophobicContact CG2-CB 4.2Å; V45-V51 HydrophobicContact CG2-CG2 3.88Å; V51-V53 HydrophobicContact CG1-CG2 3.94Å; V51-F70 HydrophobicContact CB-CB 3.69Å; V51-F70 HydrophobicContact CG1-CB 3.85Å; V51-F70 HydrophobicContact CG1-CG 4.32Å; V51-F70 WeakPolarHBondContact O-CB 3.37Å; V51-Q71 PolarHBondContact O-N 3.39Å
52T97.7Very high94.2Very high11 Ų1134.5 Ų34.57%0.06718%0.183CC..EExtended strand (participates in β ladder)trans-114.7121.6173.4-56.50000109.2I24 V26 Q71 E73 Y144I24-T52 PolarHBondContact O-N 3.07Å; V26-T52 PolarHBondContact N-O 3.24Å; T52-Q71 CarbonylContact C-O 3.58Å; T52-Q71 WeakPolarHBondContact CA-O 3.05Å; T52-E73 HydrophobicContact CG2-CB 3.65Å; T52-E73 HydrophobicContact CG2-CG 4.42Å; T52-Y144 WeakPolarHBondContact CG2-OH 3.29Å
53V97.6Very high93.7Very high0 Ų033.9 Ų33.90%018%0.183CC..EExtended strand (participates in β ladder)trans-110.4121-176.8-173.30000109.7V26 W34 L41 V51 M62 F70 Q71 Y72 E73V26-V53 HydrophobicContact CB-CB 4.29Å; V26-V53 HydrophobicContact CB-CG1 4.23Å; V26-V53 HydrophobicContact CB-CG2 3.96Å; V26-V53 HydrophobicContact CG1-CG1 4.26Å; V26-V53 HydrophobicContact CG1-CG2 4.45Å; V26-V53 HydrophobicContact CG2-CG2 4.14Å; W34-V53 HydrophobicContact CH2-CB 4.43Å; W34-V53 HydrophobicContact CH2-CG1 3.72Å; W34-V53 HydrophobicContact CH2-CG2 4.15Å; W34-V53 HydrophobicContact CZ3-CG1 3.75Å; L41-V53 HydrophobicContact CD1-CG2 3.85Å; V51-V53 HydrophobicContact CG1-CG2 3.94Å; V53-M62 HydrophobicContact CG1-CE 3.59Å; V53-F70 HydrophobicContact CB-CD2 4.35Å; V53-F70 HydrophobicContact CB-CE2 4.47Å; V53-F70 HydrophobicContact CG2-CD2 3.46Å; V53-F70 VanDerWaalsContact CG2-CD2 3.46Å; V53-F70 HydrophobicContact CG2-CE2 3.74Å; V53-F70 HydrophobicContact CG2-CG 4.21Å; V53-Q71 PolarHBondContact N-O 3.24Å; V53-Y72 HydrophobicContact CB-CD1 4Å; V53-Y72 HydrophobicContact CB-CE1 4.36Å; V53-Y72 HydrophobicContact CG1-CD1 4.34Å; V53-Y72 HydrophobicContact CG1-CE1 4.41Å; V53-Y72 CarbonylContact O-C 3.49Å; V53-Y72 WeakPolarHBondContact O-CA 3.38Å; V53-E73 PolarHBondContact O-N 2.91Å
54L97.3Very high93Very high0 Ų036.1 Ų36.10%020%0.199CC..EExtended strand (participates in β ladder)trans-66139.4171.5-65.1-178.1000110.3L25 V26 W27 Y28 E73 F75 V129 M135 L139L25-L54 HydrophobicContact CD1-CD2 4.29Å; L25-L54 HydrophobicContact CD1-CG 4.08Å; V26-L54 PolarHBondContact O-N 2.92Å; W27-L54 HydrophobicContact CD2-CD1 4.47Å; W27-L54 HydrophobicContact CE3-CD1 3.62Å; W27-L54 HydrophobicContact CH2-CD1 4.5Å; W27-L54 HydrophobicContact CZ3-CD1 3.63Å; Y28-L54 WeakPolarHBondContact CB-O 3.29Å; Y28-L54 HydrophobicContact CD1-CB 4.34Å; L54-E73 WeakPolarHBondContact CA-O 3.35Å; L54-E73 HydrophobicContact CD2-CB 4.13Å; L54-E73 HydrophobicContact CD2-CG 4.11Å; L54-F75 HydrophobicContact CB-CD1 4.25Å; L54-F75 HydrophobicContact CB-CE1 4.03Å; L54-V129 HydrophobicContact CD1-CG1 4.27Å; L54-V129 HydrophobicContact CD1-CG2 4.38Å; L54-M135 HydrophobicContact CD2-SD 4.29Å; L54-L139 HydrophobicContact CD2-CD2 4.13Å
55V95.3Very high92.1Very high4 Ų441 Ų412%0.02423%0.233CC..EExtended strand (participates in β ladder)trans-137.1120.8176.5-171.50000110.6M62 Y72 E73 P74 F75V55-M62 HydrophobicContact CG1-CB 3.93Å; V55-M62 HydrophobicContact CG1-SD 4.24Å; V55-M62 HydrophobicContact CG2-CE 3.76Å; V55-M62 HydrophobicContact CG2-SD 4.39Å; V55-Y72 HydrophobicContact CG2-CD1 3.23Å; V55-Y72 HydrophobicContact CG2-CE1 3.87Å; V55-Y72 HydrophobicContact CG2-CG 3.97Å; V55-E73 PolarHBondContact N-O 2.94Å; V55-P74 CarbonylContact O-C 3.48Å; V55-P74 WeakPolarHBondContact O-CA 3.36Å; V55-F75 VanDerWaalsContact C-CD1 3.49Å; V55-F75 VanDerWaalsContact O-CD1 3.29Å; V55-F75 WeakPolarHBondContact O-CD1 3.46Å; V55-F75 PolarHBondContact O-N 2.66Å
56P94.7Very high91.2Very high3 Ų343.9 Ų43.92%0.01925%0.245CC..EExtended strand (participates in β ladder)trans-69.1141.4174.225.5-29.6000110.1Y28 A58 S59 F75 V77 F125Y28-P56 HydrophobicContact CD2-CG 4.1Å; Y28-P56 HydrophobicContact CG-CG 4.45Å; P56-A58 PolarHBondContact O-N 2.79Å; P56-A58 VanDerWaalsContact O-N 3.09Å; P56-S59 WeakPolarHBondContact O-CB 3.45Å; P56-S59 PolarHBondContact O-N 3.05Å; P56-F75 HydrophobicContact CB-CE1 4.02Å; P56-F75 HydrophobicContact CB-CE2 3.92Å; P56-F75 HydrophobicContact CB-CZ 3.55Å; P56-F75 HydrophobicContact CG-CE1 4.46Å; P56-F75 HydrophobicContact CG-CZ 4.18Å; P56-F75 VanDerWaalsContact N-CE1 3.28Å; P56-V77 HydrophobicContact CB-CG1 4.07Å; P56-V77 HydrophobicContact CB-CG2 4.48Å; P56-F125 HydrophobicContact CB-CD1 3.7Å; P56-F125 HydrophobicContact CB-CE1 3.47Å; P56-F125 VanDerWaalsContact CB-CE1 3.47Å; P56-F125 HydrophobicContact CB-CZ 4.35Å; P56-F125 HydrophobicContact CG-CD1 3.94Å; P56-F125 HydrophobicContact CG-CE1 3.52Å
57S92.3Very high90.6Very high67 Ų6745.9 Ų45.947%0.46926%0.263SS..THydrogen-bonded Turntrans-55.5-25173.151.10000113.4F75 V77S57-F75 PolarHBondContact N-O 3.01Å; S57-F75 PolarHBondContact OG-O 2.89Å; S57-V77 PolarHBondContact OG-N 3.06Å; S57-V77 VanDerWaalsContact OG-N 3.17Å
58A91.8Very high90.1Very high3 Ų343.6 Ų43.63%0.02526%0.261CS..THydrogen-bonded Turntrans-96.524.8176.600000114.1P56 V77 V79 V81 I84 F125P56-A58 PolarHBondContact O-N 2.79Å; P56-A58 VanDerWaalsContact O-N 3.09Å; A58-V77 HydrophobicContact CB-CG2 3.53Å; A58-V79 VanDerWaalsContact CB-O 3.24Å; A58-V79 WeakPolarHBondContact CB-O 3.41Å; A58-V81 HydrophobicContact CB-CG2 4.22Å; A58-I84 HydrophobicContact CB-CD1 3.58Å; A58-I84 WeakPolarHBondContact O-CD1 3.48Å; A58-F125 HydrophobicContact CB-CZ 4.33Å
59S90.7Very high89.7Confident20 Ų2048.6 Ų48.614%0.1427%0.27CS..  trans-66.5138.8179.1-171.80000113.1E30 P56 M62E30-S59 VanDerWaalsContact CD-OG 3.27Å; E30-S59 WeakPolarHBondContact OE1-CA 3.38Å; E30-S59 VanDerWaalsContact OE1-CB 3.26Å; E30-S59 WeakPolarHBondContact OE1-CB 3.27Å; E30-S59 PolarHBondContact OE1-OG 2.81Å; E30-S59 PolarHBondContact OE2-OG 3.22Å; P56-S59 WeakPolarHBondContact O-CB 3.45Å; P56-S59 PolarHBondContact O-N 3.05Å; S59-M62 WeakPolarHBondContact OG-CB 3.28Å; S59-M62 WeakPolarHBondContact OG-CG 3.37Å; S59-M62 PolarHBondContact OG-N 3.21Å
60M86.8Confident89.5Confident47 Ų4748.4 Ų48.423%0.23227%0.269CS..SBendtrans-93.8-32.7177.4-73.7179.959.300113.1E30 V81 I84 Q85E30-M60 PolarHBondContact OE1-N 2.79Å; E30-M60 PolarHBondContact OE2-N 3.39Å; M60-V81 HydrophobicContact CG-CG1 4.01Å; M60-I84 HydrophobicContact CG-CG2 4.22Å; M60-I84 HydrophobicContact SD-CB 3.93Å; M60-I84 HydrophobicContact SD-CG2 3.43Å; M60-I84 WeakPolarHBondContact SD-CG2 3.44Å; M60-Q85 HydrophobicContact CE-CB 4.31Å; M60-Q85 HydrophobicContact SD-CB 4.41Å
61F85.8Confident89.4Confident67 Ų6747.9 Ų47.929%0.29427%0.267SS..SBendtrans-121.5-13.9-172-59.4-91000113.5E30 A31E30-F61 HydrophobicContact CB-CD2 4.23Å; E30-F61 VanDerWaalsContact OE2-CB 3.31Å; E30-F61 WeakPolarHBondContact OE2-CB 3.45Å; E30-F61 VanDerWaalsContact OE2-CD2 3.32Å; E30-F61 WeakPolarHBondContact OE2-CD2 3.41Å; E30-F61 PolarHBondContact OE2-N 2.88Å; A31-F61 HydrophobicContact CB-CD1 4.05Å; A31-F61 HydrophobicContact CB-CD2 3.68Å; A31-F61 HydrophobicContact CB-CE1 4.11Å; A31-F61 HydrophobicContact CB-CE2 3.76Å; A31-F61 HydrophobicContact CB-CG 3.84Å; A31-F61 HydrophobicContact CB-CZ 3.97Å
62M88.4Confident89.2Confident12 Ų1249 Ų496%0.05927%0.271CS..  trans-91.3123.8170.5-49.1-179.774.800109.4T29 W34 V53 V55 S59 Y72T29-M62 WeakPolarHBondContact O-CG 3.28Å; W34-M62 HydrophobicContact CD2-CE 3.79Å; W34-M62 HydrophobicContact CD2-CG 4.16Å; W34-M62 HydrophobicContact CE3-CE 3.78Å; W34-M62 HydrophobicContact CG-CG 3.95Å; W34-M62 HydrophobicContact CH2-CE 3.86Å; W34-M62 HydrophobicContact CZ2-CE 3.82Å; W34-M62 HydrophobicContact CZ3-CE 3.82Å; V53-M62 HydrophobicContact CG1-CE 3.59Å; V55-M62 HydrophobicContact CG1-CB 3.93Å; V55-M62 HydrophobicContact CG1-SD 4.24Å; V55-M62 HydrophobicContact CG2-CE 3.76Å; V55-M62 HydrophobicContact CG2-SD 4.39Å; S59-M62 WeakPolarHBondContact OG-CB 3.28Å; S59-M62 WeakPolarHBondContact OG-CG 3.37Å; S59-M62 PolarHBondContact OG-N 3.21Å; M62-Y72 HydrophobicContact CE-CE1 4.22Å
63N83Confident89.1Confident67 Ų6749.2 Ų49.236%0.35827%0.27SS..  trans-112.3104.3174.8-174.8-3000109.4S65 E66N63-S65 PolarHBondContact O-N 3.4Å; N63-S65 VanDerWaalsContact OD1-CB 3.28Å; N63-S65 WeakPolarHBondContact OD1-CB 3.2Å; N63-S65 PolarHBondContact OD1-N 2.93Å; N63-E66 HydrophobicContact CB-CG 3.84Å; N63-E66 WeakPolarHBondContact O-CB 3.37Å; N63-E66 PolarHBondContact O-N 3.44Å
64S81.2Confident89Confident60 Ų6052.8 Ų52.842%0.4229%0.294SS..THydrogen-bonded Turntrans-68.9-14.3178.2570000113.4
65S78.9Confident88.9Confident102 Ų10253 Ų5371%0.71330%0.295SS*.THydrogen-bonded Turntrans-84.2-11.4175.4-54.50000113.1N63N63-S65 PolarHBondContact O-N 3.4Å; N63-S65 VanDerWaalsContact OD1-CB 3.28Å; N63-S65 WeakPolarHBondContact OD1-CB 3.2Å; N63-S65 PolarHBondContact OD1-N 2.93Å
66E77.1Confident88.8Confident90 Ų9059.3 Ų59.342%0.42133%0.328SS..SBendtrans-69.4137.4175.1-77.9175-175.200110.6K38 N63 S68K38-E66 IonicContact NZ-OE2 3.27Å; N63-E66 HydrophobicContact CB-CG 3.84Å; N63-E66 WeakPolarHBondContact O-CB 3.37Å; N63-E66 PolarHBondContact O-N 3.44Å; E66-S68 PolarHBondContact O-N 3.37Å
67P81.3Confident88.7Confident141 Ų14160.1 Ų60.192%0.91633%0.333SS*.  trans-54116.2170.6-24.333.5000110.1
68S84.8Confident88.7Confident45 Ų4563.1 Ų63.132%0.31534%0.344SS..  trans-122.8150.7179.5-173.80000110.8E66 F70E66-S68 PolarHBondContact O-N 3.37Å; S68-F70 VanDerWaalsContact C-N 3.27Å; S68-F70 WeakPolarHBondContact CB-O 3.24Å; S68-F70 WeakPolarHBondContact OG-CD1 3.32Å; S68-F70 WeakPolarHBondContact OG-CD2 3.48Å; S68-F70 WeakPolarHBondContact OG-CE1 3.46Å; S68-F70 WeakPolarHBondContact OG-CE2 3.17Å; S68-F70 VanDerWaalsContact OG-CG 3.28Å; S68-F70 WeakPolarHBondContact OG-CG 3.47Å; S68-F70 WeakPolarHBondContact OG-CZ 3.45Å; S68-F70 PolarHBondContact OG-N 3.38Å; S68-F70 PolarHBondContact OG-O 3Å
69R88Confident88.6Confident136 Ų13663.9 Ų63.951%0.51335%0.348SS..SBendtrans-84.4-5.3174.2-59-177.163.2-161.1-1.6112.6V45 D46V45-R69 HydrophobicContact CG1-CB 4.11Å; V45-R69 WeakPolarHBondContact CG1-O 3.31Å; D46-R69 VanDerWaalsContact CG-NH1 3.3Å; D46-R69 IonicContact OD1-CZ 3.97Å; D46-R69 IonicContact OD1-NH1 3.76Å; D46-R69 PolarHBondContact OD1-NH1 3.41Å; D46-R69 IonicContact OD1-NH2 3.36Å; D46-R69 PolarHBondContact OD1-NH2 2.97Å; D46-R69 IonicContact OD2-NH1 3.1Å; D46-R69 PolarHBondContact OD2-NH1 2.88Å
70F92.4Very high88.6Confident17 Ų1765.4 Ų65.48%0.07536%0.359CS..SBendtrans-125.4160.3177.548.7-102.3000110.6W34 K38 L41 V45 V51 V53 S68 Y72W34-F70 AromaticContact CH2-CE2 3.6Å; W34-F70 HydrophobicContact CH2-CE2 3.6Å; W34-F70 AromaticContact CH2-CZ 3.57Å; W34-F70 HydrophobicContact CH2-CZ 3.57Å; W34-F70 AromaticContact CZ2-CE2 3.88Å; W34-F70 HydrophobicContact CZ2-CE2 3.88Å; W34-F70 AromaticContact CZ2-CZ 3.73Å; W34-F70 HydrophobicContact CZ2-CZ 3.73Å; K38-F70 HydrophobicContact CG-CZ 4.47Å; L41-F70 HydrophobicContact CB-CD1 4.1Å; L41-F70 HydrophobicContact CB-CE1 4.12Å; L41-F70 HydrophobicContact CD1-CE1 4.38Å; L41-F70 HydrophobicContact CD1-CZ 4.39Å; V45-F70 HydrophobicContact CG2-CB 4.14Å; V51-F70 HydrophobicContact CB-CB 3.69Å; V51-F70 HydrophobicContact CG1-CB 3.85Å; V51-F70 HydrophobicContact CG1-CG 4.32Å; V51-F70 WeakPolarHBondContact O-CB 3.37Å; V53-F70 HydrophobicContact CB-CD2 4.35Å; V53-F70 HydrophobicContact CB-CE2 4.47Å; V53-F70 HydrophobicContact CG2-CD2 3.46Å; V53-F70 VanDerWaalsContact CG2-CD2 3.46Å; V53-F70 HydrophobicContact CG2-CE2 3.74Å; V53-F70 HydrophobicContact CG2-CG 4.21Å; S68-F70 VanDerWaalsContact C-N 3.27Å; S68-F70 WeakPolarHBondContact CB-O 3.24Å; S68-F70 WeakPolarHBondContact OG-CD1 3.32Å; S68-F70 WeakPolarHBondContact OG-CD2 3.48Å; S68-F70 WeakPolarHBondContact OG-CE1 3.46Å; S68-F70 WeakPolarHBondContact OG-CE2 3.17Å; S68-F70 VanDerWaalsContact OG-CG 3.28Å; S68-F70 WeakPolarHBondContact OG-CG 3.47Å; S68-F70 WeakPolarHBondContact OG-CZ 3.45Å; S68-F70 PolarHBondContact OG-N 3.38Å; S68-F70 PolarHBondContact OG-O 3Å; F70-Y72 HydrophobicContact CD2-CE1 4.33Å; F70-Y72 HydrophobicContact CE2-CD1 4.24Å; F70-Y72 AromaticContact CE2-CE1 3.58Å; F70-Y72 HydrophobicContact CE2-CE1 3.58Å; F70-Y72 HydrophobicContact CE2-CE2 4.27Å; F70-Y72 AromaticContact CE2-CZ 3.61Å
71Q93.7Very high88.8Confident108 Ų10866.5 Ų66.551%0.50537%0.368SS..EExtended strand (participates in β ladder)trans-81.6131.9-177.6-179.1174.8-6.500110.5V51 T52 V53V51-Q71 PolarHBondContact O-N 3.39Å; T52-Q71 CarbonylContact C-O 3.58Å; T52-Q71 WeakPolarHBondContact CA-O 3.05Å; V53-Q71 PolarHBondContact N-O 3.24Å
72Y95.1Very high89Confident30 Ų3071.8 Ų71.812%0.11839%0.391CS..EExtended strand (participates in β ladder)trans-91.3138.9165-69.2-65.3000110.3W34 V53 V55 M62 F70W34-Y72 HydrophobicContact CH2-CE1 4.12Å; W34-Y72 AromaticContact CZ2-CE1 3.76Å; W34-Y72 HydrophobicContact CZ2-CE1 3.76Å; W34-Y72 WeakPolarHBondContact CZ2-OH 3.43Å; V53-Y72 HydrophobicContact CB-CD1 4Å; V53-Y72 HydrophobicContact CB-CE1 4.36Å; V53-Y72 HydrophobicContact CG1-CD1 4.34Å; V53-Y72 HydrophobicContact CG1-CE1 4.41Å; V53-Y72 CarbonylContact O-C 3.49Å; V53-Y72 WeakPolarHBondContact O-CA 3.38Å; V55-Y72 HydrophobicContact CG2-CD1 3.23Å; V55-Y72 HydrophobicContact CG2-CE1 3.87Å; V55-Y72 HydrophobicContact CG2-CG 3.97Å; M62-Y72 HydrophobicContact CE-CE1 4.22Å; F70-Y72 HydrophobicContact CD2-CE1 4.33Å; F70-Y72 HydrophobicContact CE2-CD1 4.24Å; F70-Y72 AromaticContact CE2-CE1 3.58Å; F70-Y72 HydrophobicContact CE2-CE1 3.58Å; F70-Y72 HydrophobicContact CE2-CE2 4.27Å; F70-Y72 AromaticContact CE2-CZ 3.61Å
73E95.3Very high89.1Confident14 Ų1475.2 Ų75.27%0.06541%0.409CS..EExtended strand (participates in β ladder)trans-121.492.8176.4-173.558-13200108.4T52 V53 L54 V55 M135 K138T52-E73 HydrophobicContact CG2-CB 3.65Å; T52-E73 HydrophobicContact CG2-CG 4.42Å; V53-E73 PolarHBondContact O-N 2.91Å; L54-E73 WeakPolarHBondContact CA-O 3.35Å; L54-E73 HydrophobicContact CD2-CB 4.13Å; L54-E73 HydrophobicContact CD2-CG 4.11Å; V55-E73 PolarHBondContact N-O 2.94Å; E73-M135 HydrophobicContact CG-CE 4.32Å; E73-M135 HydrophobicContact CG-SD 4.22Å; E73-K138 WeakPolarHBondContact OE1-CD 3.23Å; E73-K138 VanDerWaalsContact OE1-CE 3.24Å; E73-K138 WeakPolarHBondContact OE1-CE 3.36Å; E73-K138 IonicContact OE1-NZ 2.61Å; E73-K138 PolarHBondContact OE1-NZ 3.16Å; E73-K138 WeakPolarHBondContact OE2-CE 3.29Å; E73-K138 IonicContact OE2-NZ 2.73Å; E73-K138 PolarHBondContact OE2-NZ 3.2Å
74P94.5Very high89.3Confident75 Ų7572.6 Ų72.649%0.48740%0.395SS..EExtended strand (participates in β ladder)trans-71.9147.1-176.529.5-33.7000111.5V55 M135V55-P74 CarbonylContact O-C 3.48Å; V55-P74 WeakPolarHBondContact O-CA 3.36Å; P74-M135 WeakPolarHBondContact O-CE 3.43Å
75F95.1Very high89.8Confident5 Ų572.7 Ų72.72%0.02239%0.389CS..EExtended strand (participates in β ladder)trans-135.5145172.767.6-88000111.8Y28 L54 V55 P56 S57 V77 F125 V129 M135Y28-F75 AromaticContact CD1-CE1 3.59Å; Y28-F75 HydrophobicContact CD1-CE1 3.59Å; Y28-F75 AromaticContact CD1-CZ 3.46Å; Y28-F75 HydrophobicContact CD1-CZ 3.46Å; Y28-F75 VanDerWaalsContact CD1-CZ 3.46Å; Y28-F75 HydrophobicContact CD2-CZ 4.42Å; Y28-F75 HydrophobicContact CE1-CE1 4.13Å; Y28-F75 HydrophobicContact CE1-CE2 4.46Å; Y28-F75 AromaticContact CE1-CZ 3.55Å; Y28-F75 HydrophobicContact CE1-CZ 3.55Å; Y28-F75 HydrophobicContact CE2-CZ 4.5Å; Y28-F75 HydrophobicContact CG-CE1 4.02Å; Y28-F75 AromaticContact CG-CZ 3.95Å; Y28-F75 HydrophobicContact CG-CZ 3.95Å; L54-F75 HydrophobicContact CB-CD1 4.25Å; L54-F75 HydrophobicContact CB-CE1 4.03Å; V55-F75 VanDerWaalsContact C-CD1 3.49Å; V55-F75 VanDerWaalsContact O-CD1 3.29Å; V55-F75 WeakPolarHBondContact O-CD1 3.46Å; V55-F75 PolarHBondContact O-N 2.66Å; P56-F75 HydrophobicContact CB-CE1 4.02Å; P56-F75 HydrophobicContact CB-CE2 3.92Å; P56-F75 HydrophobicContact CB-CZ 3.55Å; P56-F75 HydrophobicContact CG-CE1 4.46Å; P56-F75 HydrophobicContact CG-CZ 4.18Å; P56-F75 VanDerWaalsContact N-CE1 3.28Å; S57-F75 PolarHBondContact N-O 3.01Å; S57-F75 PolarHBondContact OG-O 2.89Å; F75-V77 HydrophobicContact CD2-CG1 3.63Å; F75-V77 HydrophobicContact CE2-CG1 3.32Å; F75-V77 HydrophobicContact CZ-CG1 4.35Å; F75-F125 WeakPolarHBondContact CE2-O 3.24Å; F75-V129 HydrophobicContact CD1-CG2 4.1Å; F75-V129 HydrophobicContact CD2-CG2 3.76Å; F75-V129 HydrophobicContact CE1-CG2 4.03Å; F75-V129 HydrophobicContact CE2-CG2 3.67Å; F75-V129 HydrophobicContact CG-CG2 3.97Å; F75-V129 HydrophobicContact CZ-CG2 3.82Å; F75-M135 HydrophobicContact CB-CE 3.65Å
76D94.1Very high90.4Very high136 Ų13674.2 Ų74.273%0.72738%0.383SS*.  trans-79.1140.4-178.3-65.6-35000111.1G128D76-G128 VanDerWaalsContact O-CA 3.28Å; D76-G128 WeakPolarHBondContact O-CA 3.48Å
77V93.2Very high91Very high20 Ų2071.8 Ų71.812%0.12137%0.372CS..  trans-131.6143.6177.4-60.70000110.1P56 S57 A58 F75 V79 F125P56-V77 HydrophobicContact CB-CG1 4.07Å; P56-V77 HydrophobicContact CB-CG2 4.48Å; S57-V77 PolarHBondContact OG-N 3.06Å; S57-V77 VanDerWaalsContact OG-N 3.17Å; A58-V77 HydrophobicContact CB-CG2 3.53Å; F75-V77 HydrophobicContact CD2-CG1 3.63Å; F75-V77 HydrophobicContact CE2-CG1 3.32Å; F75-V77 HydrophobicContact CZ-CG1 4.35Å; V77-V79 HydrophobicContact CG2-CB 4.37Å; V77-V79 PolarHBondContact O-N 2.86Å; V77-F125 HydrophobicContact CB-CD2 4.4Å; V77-F125 HydrophobicContact CG1-CB 4.39Å; V77-F125 HydrophobicContact CG1-CD1 4.35Å; V77-F125 HydrophobicContact CG1-CD2 4.36Å; V77-F125 HydrophobicContact CG1-CG 4.12Å; V77-F125 HydrophobicContact CG2-CE2 4.24Å; V77-F125 HydrophobicContact CG2-CZ 4.39Å
78D91.1Very high91.3Very high131 Ų13166.6 Ų66.670%0.70134%0.336SS*.SBendtrans-83.651.6176.5-174.838.7000111.7
79V89.4Confident91.7Very high19 Ų1968.1 Ų68.112%0.11534%0.34CS..SBendtrans-147.3136.9179.5-176.50000108.2A58 V77 D83 I84 M121 K124 F125A58-V79 VanDerWaalsContact CB-O 3.24Å; A58-V79 WeakPolarHBondContact CB-O 3.41Å; V77-V79 HydrophobicContact CG2-CB 4.37Å; V77-V79 PolarHBondContact O-N 2.86Å; V79-D83 HydrophobicContact CG1-CB 3.98Å; V79-I84 HydrophobicContact CG1-CD1 4.27Å; V79-I84 HydrophobicContact CG1-CG1 3.83Å; V79-M121 HydrophobicContact CG1-CG 4.17Å; V79-M121 HydrophobicContact CG1-SD 4.3Å; V79-M121 HydrophobicContact CG2-CG 4.29Å; V79-K124 HydrophobicContact CG2-CB 3.74Å; V79-K124 HydrophobicContact CG2-CD 3.58Å; V79-K124 HydrophobicContact CG2-CG 4.35Å; V79-F125 HydrophobicContact CB-CE2 3.91Å; V79-F125 HydrophobicContact CG1-CE2 4.13Å; V79-F125 HydrophobicContact CG2-CD2 4.16Å; V79-F125 HydrophobicContact CG2-CE2 3.99Å
80S91.5Very high91.9Very high52 Ų5265.5 Ų65.536%0.36434%0.336SS..  trans-89.1154.9174.7790000112.1K82 D83 I84S80-K82 PolarHBondContact O-N 2.96Å; S80-K82 VanDerWaalsContact O-N 3.15Å; S80-K82 PolarHBondContact OG-N 3.28Å; S80-D83 WeakPolarHBondContact CB-OD2 3.47Å; S80-D83 PolarHBondContact N-OD2 3.12Å; S80-D83 PolarHBondContact O-N 3.47Å; S80-D83 PolarHBondContact OG-N 3.32Å; S80-D83 PolarHBondContact OG-OD2 2.91Å; S80-I84 PolarHBondContact O-N 3.34Å
81V90.1Very high91.9Very high69 Ų6968.1 Ų68.142%0.41835%0.35SS..Hα-helixtrans-54.8-32.7171.8179.90000111.8A58 M60 I84 Q85A58-V81 HydrophobicContact CB-CG2 4.22Å; M60-V81 HydrophobicContact CG-CG1 4.01Å; V81-I84 PolarHBondContact O-N 3.2Å; V81-Q85 WeakPolarHBondContact O-CB 3.14Å; V81-Q85 PolarHBondContact O-N 3.49Å
82K90.6Very high91.8Very high179 Ų17963.7 Ų63.778%0.77833%0.33SS*.Hα-helixtrans-68.2-36.6178.6-68.8-177.8179.6177.50112.5S80 I84 Q85 K86S80-K82 PolarHBondContact O-N 2.96Å; S80-K82 VanDerWaalsContact O-N 3.15Å; S80-K82 PolarHBondContact OG-N 3.28Å; K82-I84 VanDerWaalsContact C-N 3.34Å; K82-Q85 PolarHBondContact O-N 2.87Å; K82-K86 WeakPolarHBondContact O-CB 3.45Å; K82-K86 PolarHBondContact O-N 2.88Å
83D89.9Confident91.7Very high83 Ų8366.9 Ų66.944%0.44435%0.346SS..Hα-helixtrans-66.2-41.4178.3-59-47.8000110.7V79 S80 K86 I87V79-D83 HydrophobicContact CG1-CB 3.98Å; S80-D83 WeakPolarHBondContact CB-OD2 3.47Å; S80-D83 PolarHBondContact N-OD2 3.12Å; S80-D83 PolarHBondContact O-N 3.47Å; S80-D83 PolarHBondContact OG-N 3.32Å; S80-D83 PolarHBondContact OG-OD2 2.91Å; D83-K86 PolarHBondContact O-N 3.29Å; D83-I87 PolarHBondContact O-N 2.93Å; D83-I87 VanDerWaalsContact O-N 3.09Å
84I88.9Confident91.7Very high12 Ų1266.4 Ų66.46%0.06234%0.344CS..Hα-helixtrans-65.8-46.4177-54.9159.4000109.9A58 M60 V79 S80 V81 K82 K86 I87 F88 M121 F125A58-I84 HydrophobicContact CB-CD1 3.58Å; A58-I84 WeakPolarHBondContact O-CD1 3.48Å; M60-I84 HydrophobicContact CG-CG2 4.22Å; M60-I84 HydrophobicContact SD-CB 3.93Å; M60-I84 HydrophobicContact SD-CG2 3.43Å; M60-I84 WeakPolarHBondContact SD-CG2 3.44Å; V79-I84 HydrophobicContact CG1-CD1 4.27Å; V79-I84 HydrophobicContact CG1-CG1 3.83Å; S80-I84 PolarHBondContact O-N 3.34Å; V81-I84 PolarHBondContact O-N 3.2Å; K82-I84 VanDerWaalsContact C-N 3.34Å; I84-K86 PolarHBondContact O-N 3.35Å; I84-I87 PolarHBondContact O-N 3.24Å; I84-F88 VanDerWaalsContact O-CB 3.25Å; I84-F88 WeakPolarHBondContact O-CB 3.38Å; I84-F88 PolarHBondContact O-N 3.3Å; I84-M121 HydrophobicContact CB-SD 4.21Å; I84-M121 HydrophobicContact CG1-SD 3.61Å; I84-M121 HydrophobicContact CG2-CE 4.4Å; I84-M121 HydrophobicContact CG2-SD 4.36Å; I84-F125 HydrophobicContact CD1-CE2 4.12Å; I84-F125 HydrophobicContact CD1-CZ 3.56Å; I84-F125 HydrophobicContact CG1-CE2 4.45Å; I84-F125 HydrophobicContact CG1-CZ 4.25Å
85Q90.4Very high91.7Very high62 Ų6263.4 Ų63.429%0.2933%0.325SS..Hα-helixtrans-57-40.8176.6-177.466.268.500111.1M60 V81 K82 F88 D89M60-Q85 HydrophobicContact CE-CB 4.31Å; M60-Q85 HydrophobicContact SD-CB 4.41Å; V81-Q85 WeakPolarHBondContact O-CB 3.14Å; V81-Q85 PolarHBondContact O-N 3.49Å; K82-Q85 PolarHBondContact O-N 2.87Å; Q85-F88 WeakPolarHBondContact O-CB 3.12Å; Q85-F88 PolarHBondContact O-N 3.03Å; Q85-D89 VanDerWaalsContact NE2-CG 3.32Å; Q85-D89 PolarHBondContact NE2-OD1 2.64Å; Q85-D89 PolarHBondContact NE2-OD2 2.69Å; Q85-D89 WeakPolarHBondContact O-CB 3.18Å; Q85-D89 PolarHBondContact O-N 3.33Å
86K91.3Very high91.6Very high134 Ų13463.7 Ų63.758%0.58333%0.326SS*.Hα-helixtrans-64-50177.5-177.1-177.9175.2-173.40112.5K82 D83 I84 F88 D89 D90K82-K86 WeakPolarHBondContact O-CB 3.45Å; K82-K86 PolarHBondContact O-N 2.88Å; D83-K86 PolarHBondContact O-N 3.29Å; I84-K86 PolarHBondContact O-N 3.35Å; K86-F88 PolarHBondContact O-N 3.44Å; K86-D89 PolarHBondContact O-N 2.76Å; K86-D90 WeakPolarHBondContact O-CB 3.22Å; K86-D90 VanDerWaalsContact O-CG 3.3Å; K86-D90 PolarHBondContact O-N 3.01Å
87I89.4Confident91.6Very high39 Ų3959.6 Ų59.620%0.230%0.301CS..Hα-helixtrans-58.7-40.1178-68.6175.1000110.3D83 I84 L91 M121D83-I87 PolarHBondContact O-N 2.93Å; D83-I87 VanDerWaalsContact O-N 3.09Å; I84-I87 PolarHBondContact O-N 3.24Å; I87-L91 WeakPolarHBondContact O-CB 3.28Å; I87-L91 PolarHBondContact O-N 2.87Å; I87-M121 HydrophobicContact CD1-CB 4.25Å; I87-M121 HydrophobicContact CD1-CE 4.15Å; I87-M121 HydrophobicContact CD1-SD 3.68Å
88F89.4Confident91.7Very high33 Ų3361 Ų6115%0.14531%0.306CS..Hα-helixtrans-64.4-46.3177.6-174.2-99.9000112.5I84 Q85 K86 L91 L92 M311I84-F88 VanDerWaalsContact O-CB 3.25Å; I84-F88 WeakPolarHBondContact O-CB 3.38Å; I84-F88 PolarHBondContact O-N 3.3Å; Q85-F88 WeakPolarHBondContact O-CB 3.12Å; Q85-F88 PolarHBondContact O-N 3.03Å; K86-F88 PolarHBondContact O-N 3.44Å; F88-L91 PolarHBondContact O-N 3.44Å; F88-L92 HydrophobicContact CD1-CD1 3.97Å; F88-L92 HydrophobicContact CD1-CG 4.37Å; F88-L92 HydrophobicContact CE1-CD1 3.23Å; F88-L92 HydrophobicContact CE1-CG 3.87Å; F88-L92 HydrophobicContact CE2-CG 4.47Å; F88-L92 HydrophobicContact CZ-CD1 3.59Å; F88-L92 HydrophobicContact CZ-CD2 4.19Å; F88-L92 HydrophobicContact CZ-CG 3.88Å; F88-L92 WeakPolarHBondContact O-CG 3.29Å; F88-L92 PolarHBondContact O-N 3.02Å; F88-M311 HydrophobicContact CE1-CB 4.32Å; F88-M311 HydrophobicContact CE1-CG 4.36Å; F88-M311 HydrophobicContact CE2-CE 3.92Å; F88-M311 HydrophobicContact CE2-CG 4.01Å; F88-M311 HydrophobicContact CE2-SD 3.55Å; F88-M311 VanDerWaalsContact CE2-SD 3.55Å; F88-M311 HydrophobicContact CZ-CB 3.62Å; F88-M311 HydrophobicContact CZ-CE 4.31Å; F88-M311 HydrophobicContact CZ-CG 3.41Å; F88-M311 VanDerWaalsContact CZ-CG 3.41Å; F88-M311 HydrophobicContact CZ-SD 3.52Å; F88-M311 VanDerWaalsContact CZ-SD 3.52Å
89D91.5Very high91.8Very high77 Ų7757.5 Ų57.541%0.41229%0.286SS..Hα-helixtrans-64.6-41177.5-69.6-19.7000111.6Q85 K86 L91 L92 H93Q85-D89 VanDerWaalsContact NE2-CG 3.32Å; Q85-D89 PolarHBondContact NE2-OD1 2.64Å; Q85-D89 PolarHBondContact NE2-OD2 2.69Å; Q85-D89 WeakPolarHBondContact O-CB 3.18Å; Q85-D89 PolarHBondContact O-N 3.33Å; K86-D89 PolarHBondContact O-N 2.76Å; D89-L91 PolarHBondContact O-N 3.41Å; D89-L92 PolarHBondContact O-N 2.76Å; D89-H93 VanDerWaalsContact O-CB 3.26Å; D89-H93 WeakPolarHBondContact O-CB 3.41Å; D89-H93 PolarHBondContact O-N 3.08Å
90D92.3Very high92.1Very high80 Ų8059.7 Ų59.743%0.42830%0.297SS..Hα-helixtrans-62-42.9176.3-71.8-19.2000111.2K86 F94 L114K86-D90 WeakPolarHBondContact O-CB 3.22Å; K86-D90 VanDerWaalsContact O-CG 3.3Å; K86-D90 PolarHBondContact O-N 3.01Å; D90-F94 VanDerWaalsContact O-CB 3.31Å; D90-F94 WeakPolarHBondContact O-CB 3.34Å; D90-F94 PolarHBondContact O-N 3.37Å; D90-L114 HydrophobicContact CB-CD2 4.3Å
91L92.2Very high92.2Very high72 Ų7263.8 Ų63.838%0.37731%0.309SS..Hα-helixtrans-64.4-45.5176.5176.965.7000112I87 F88 D89 S95 L114I87-L91 WeakPolarHBondContact O-CB 3.28Å; I87-L91 PolarHBondContact O-N 2.87Å; F88-L91 PolarHBondContact O-N 3.44Å; D89-L91 PolarHBondContact O-N 3.41Å; L91-S95 WeakPolarHBondContact O-CB 3.39Å; L91-S95 PolarHBondContact O-N 3.31Å; L91-S95 PolarHBondContact O-OG 2.98Å; L91-L114 HydrophobicContact CD1-CD1 4.13Å
92L92.9Very high92.5Very high16 Ų1663.1 Ų63.18%0.08430%0.302CS..Hα-helixtrans-64.8-45.5177.9-75.8-172.1000111.2F88 D89 F94 S95 M96 F395F88-L92 HydrophobicContact CD1-CD1 3.97Å; F88-L92 HydrophobicContact CD1-CG 4.37Å; F88-L92 HydrophobicContact CE1-CD1 3.23Å; F88-L92 HydrophobicContact CE1-CG 3.87Å; F88-L92 HydrophobicContact CE2-CG 4.47Å; F88-L92 HydrophobicContact CZ-CD1 3.59Å; F88-L92 HydrophobicContact CZ-CD2 4.19Å; F88-L92 HydrophobicContact CZ-CG 3.88Å; F88-L92 WeakPolarHBondContact O-CG 3.29Å; F88-L92 PolarHBondContact O-N 3.02Å; D89-L92 PolarHBondContact O-N 2.76Å; L92-F94 PolarHBondContact O-N 3.17Å; L92-S95 PolarHBondContact O-N 3.32Å; L92-M96 HydrophobicContact CB-SD 4.32Å; L92-M96 VanDerWaalsContact O-CB 3.25Å; L92-M96 WeakPolarHBondContact O-CB 3.09Å; L92-M96 VanDerWaalsContact O-CG 3.24Å; L92-M96 WeakPolarHBondContact O-CG 3.39Å; L92-M96 PolarHBondContact O-N 3.21Å; L92-F395 HydrophobicContact CD2-CB 4.35Å; L92-F395 HydrophobicContact CD2-CD1 3.44Å; L92-F395 VanDerWaalsContact CD2-CD1 3.44Å; L92-F395 HydrophobicContact CD2-CD2 4.18Å; L92-F395 HydrophobicContact CD2-CE1 3.68Å; L92-F395 HydrophobicContact CD2-CE2 4.39Å; L92-F395 HydrophobicContact CD2-CG 3.74Å; L92-F395 HydrophobicContact CD2-CZ 4.17Å
93H93.3Very high92.7Very high97 Ų9758.4 Ų58.445%0.44929%0.285SS..Hα-helixtrans-60.8-48.3-179.8-172.472.6000111.4D89 S95 M96 Y97 E98D89-H93 VanDerWaalsContact O-CB 3.26Å; D89-H93 WeakPolarHBondContact O-CB 3.41Å; D89-H93 PolarHBondContact O-N 3.08Å; H93-S95 PolarHBondContact O-N 2.88Å; H93-M96 PolarHBondContact O-N 3.21Å; H93-Y97 AromaticContact ND1-CD2 3.59Å; H93-Y97 PolarHBondContact O-N 3.31Å; H93-E98 IonicContact CD2-OE1 3.85Å; H93-E98 PolarHBondContact CD2-OE1 3.21Å; H93-E98 VanDerWaalsContact CD2-OE1 3.25Å; H93-E98 IonicContact NE2-OE1 3.9Å
94F94.8Very high92.8Very high3 Ų359 Ų591%0.01329%0.294CS..Iπ-helixtrans-55.1-51.4174.4167.8-119.7000111.8D90 L92 E98 M99 M102 I107 K110 L114D90-F94 VanDerWaalsContact O-CB 3.31Å; D90-F94 WeakPolarHBondContact O-CB 3.34Å; D90-F94 PolarHBondContact O-N 3.37Å; L92-F94 PolarHBondContact O-N 3.17Å; F94-E98 HydrophobicContact CD2-CB 4.21Å; F94-E98 PolarHBondContact O-N 3Å; F94-M99 HydrophobicContact CD1-CE 4.03Å; F94-M99 HydrophobicContact CE1-CE 3.43Å; F94-M99 VanDerWaalsContact CE1-CE 3.43Å; F94-M99 HydrophobicContact CE2-CB 4.35Å; F94-M99 HydrophobicContact CZ-CB 4.5Å; F94-M99 HydrophobicContact CZ-CE 3.8Å; F94-M99 HydrophobicContact CZ-CG 4.46Å; F94-M99 WeakPolarHBondContact O-CB 3.46Å; F94-M99 PolarHBondContact O-N 2.83Å; F94-M102 HydrophobicContact CD2-SD 4.44Å; F94-M102 HydrophobicContact CE2-SD 3.81Å; F94-I107 HydrophobicContact CZ-CG2 4.19Å; F94-K110 HydrophobicContact CD1-CG 4.49Å; F94-K110 HydrophobicContact CD2-CB 4.47Å; F94-K110 HydrophobicContact CD2-CD 3.39Å; F94-K110 VanDerWaalsContact CD2-CE 3.41Å; F94-K110 HydrophobicContact CD2-CG 3.77Å; F94-K110 HydrophobicContact CE1-CG 4.39Å; F94-K110 HydrophobicContact CE2-CB 3.87Å; F94-K110 HydrophobicContact CE2-CD 3.58Å; F94-K110 HydrophobicContact CE2-CG 3.66Å; F94-K110 HydrophobicContact CG-CD 4.09Å; F94-K110 HydrophobicContact CG-CG 4.18Å; F94-K110 HydrophobicContact CZ-CB 3.96Å; F94-K110 HydrophobicContact CZ-CD 4.4Å; F94-K110 HydrophobicContact CZ-CG 3.98Å; F94-L114 HydrophobicContact CB-CD1 4.08Å; F94-L114 HydrophobicContact CD1-CD1 3.42Å; F94-L114 VanDerWaalsContact CD1-CD1 3.42Å; F94-L114 HydrophobicContact CE1-CD1 4.05Å; F94-L114 HydrophobicContact CG-CD1 3.9Å
95S94.2Very high92.9Very high13 Ų1365.4 Ų65.49%0.09132%0.321CS..Iπ-helixtrans-66.3-42.5-175.3-56.80000112.7L91 L92 H93 M394 F395L91-S95 WeakPolarHBondContact O-CB 3.39Å; L91-S95 PolarHBondContact O-N 3.31Å; L91-S95 PolarHBondContact O-OG 2.98Å; L92-S95 PolarHBondContact O-N 3.32Å; H93-S95 PolarHBondContact O-N 2.88Å; S95-M394 CarbonylContact C-O 3.56Å; S95-F395 VanDerWaalsContact CB-CB 3.47Å
96M94.3Very high93Very high10 Ų1066.9 Ų66.95%0.04933%0.328CS..Iπ-helixtrans-82.5-36.7-171.6-68.7174.460.700113L92 H93 V312 L315 M394 L416 N417L92-M96 HydrophobicContact CB-SD 4.32Å; L92-M96 VanDerWaalsContact O-CB 3.25Å; L92-M96 WeakPolarHBondContact O-CB 3.09Å; L92-M96 VanDerWaalsContact O-CG 3.24Å; L92-M96 WeakPolarHBondContact O-CG 3.39Å; L92-M96 PolarHBondContact O-N 3.21Å; H93-M96 PolarHBondContact O-N 3.21Å; M96-V312 HydrophobicContact CE-CG1 4.04Å; M96-V312 HydrophobicContact CE-CG2 4.48Å; M96-V312 HydrophobicContact SD-CG2 4.09Å; M96-L315 HydrophobicContact CE-CD2 3.78Å; M96-M394 HydrophobicContact CE-SD 3.83Å; M96-M394 HydrophobicContact CG-CB 4.03Å; M96-M394 WeakPolarHBondContact CG-O 3.29Å; M96-M394 HydrophobicContact SD-CB 4.42Å; M96-L416 HydrophobicContact CB-CD2 4.4Å; M96-L416 HydrophobicContact CE-CD2 4.15Å; M96-N417 PolarHBondContact O-ND2 2.95Å; M96-N417 PolarHBondContact O-OD1 2.88Å
97Y94.1Very high93.1Very high51 Ų5162.5 Ų62.520%0.231%0.311CS..Iπ-helixtrans-123.6-16.3-165.4-57.4-66.6000114.8H93 F101 T316 L416H93-Y97 AromaticContact ND1-CD2 3.59Å; H93-Y97 PolarHBondContact O-N 3.31Å; Y97-F101 VanDerWaalsContact O-CD2 3.24Å; Y97-F101 WeakPolarHBondContact O-CD2 3.43Å; Y97-F101 VanDerWaalsContact O-CE2 3.28Å; Y97-F101 WeakPolarHBondContact O-CE2 3.31Å; Y97-T316 HydrophobicContact CE1-CG2 3.82Å; Y97-L416 HydrophobicContact CE1-CD2 4.25Å
98E94.6Very high93.1Very high50 Ų5063.9 Ų63.923%0.23431%0.314CS..Iπ-helixtrans-111.3-41.7-177.2-60.7-174.9-151.300113.3H93 F94 D100 F101 M102 K110H93-E98 IonicContact CD2-OE1 3.85Å; H93-E98 PolarHBondContact CD2-OE1 3.21Å; H93-E98 VanDerWaalsContact CD2-OE1 3.25Å; H93-E98 IonicContact NE2-OE1 3.9Å; F94-E98 HydrophobicContact CD2-CB 4.21Å; F94-E98 PolarHBondContact O-N 3Å; E98-D100 VanDerWaalsContact C-N 3.29Å; E98-D100 PolarHBondContact O-N 3.09Å; E98-F101 PolarHBondContact O-N 3.01Å; E98-M102 HydrophobicContact CB-CE 3.93Å; E98-M102 WeakPolarHBondContact OE2-CE 3.41Å; E98-K110 IonicContact OE1-NZ 3.61Å; E98-K110 PolarHBondContact OE1-NZ 2.98Å; E98-K110 VanDerWaalsContact OE1-NZ 3.11Å; E98-K110 IonicContact OE2-NZ 2.82Å; E98-K110 PolarHBondContact OE2-NZ 3.13Å
99M93.9Very high93.2Very high57 Ų5767.3 Ų67.328%0.28133%0.332SS..G310 helixtrans-55.5-40.4-169.9-174.6-175.5-68.900113.1F94 F101 M102 I107F94-M99 HydrophobicContact CD1-CE 4.03Å; F94-M99 HydrophobicContact CE1-CE 3.43Å; F94-M99 VanDerWaalsContact CE1-CE 3.43Å; F94-M99 HydrophobicContact CE2-CB 4.35Å; F94-M99 HydrophobicContact CZ-CB 4.5Å; F94-M99 HydrophobicContact CZ-CE 3.8Å; F94-M99 HydrophobicContact CZ-CG 4.46Å; F94-M99 WeakPolarHBondContact O-CB 3.46Å; F94-M99 PolarHBondContact O-N 2.83Å; M99-F101 PolarHBondContact O-N 2.9Å; M99-M102 PolarHBondContact O-N 2.87Å; M99-I107 HydrophobicContact CE-CG2 4.39Å; M99-I107 HydrophobicContact CG-CD1 3.84Å; M99-I107 HydrophobicContact CG-CG1 3.98Å; M99-I107 HydrophobicContact CG-CG2 4.02Å; M99-I107 WeakPolarHBondContact O-CD1 3.25Å; M99-I107 HydrophobicContact SD-CG2 4.36Å
100D93.9Very high93.3Very high64 Ų6466.8 Ų66.834%0.34233%0.326SS..G310 helixtrans-66.6-15-179.4-79-19000113.8E98 N415 N417 F418E98-D100 VanDerWaalsContact C-N 3.29Å; E98-D100 PolarHBondContact O-N 3.09Å; D100-N415 PolarHBondContact OD2-ND2 3.43Å; D100-N415 PolarHBondContact OD2-OD1 3.27Å; D100-N417 PolarHBondContact OD2-ND2 2.89Å; D100-F418 HydrophobicContact CB-CE2 4.03Å; D100-F418 HydrophobicContact CB-CZ 4.05Å
101F95.1Very high93.1Very high138 Ų13864.6 Ų64.661%0.60532%0.319SS*.G310 helixtrans-106.84.1-179.4-53.6-73.9000113Y97 E98 M99 N417 F418Y97-F101 VanDerWaalsContact O-CD2 3.24Å; Y97-F101 WeakPolarHBondContact O-CD2 3.43Å; Y97-F101 VanDerWaalsContact O-CE2 3.28Å; Y97-F101 WeakPolarHBondContact O-CE2 3.31Å; E98-F101 PolarHBondContact O-N 3.01Å; M99-F101 PolarHBondContact O-N 2.9Å; F101-N417 HydrophobicContact CE2-CB 4.3Å; F101-N417 HydrophobicContact CZ-CB 3.96Å; F101-F418 AromaticContact CE1-CE1 3.8Å; F101-F418 HydrophobicContact CE1-CE1 3.8Å; F101-F418 HydrophobicContact CE1-CZ 4.11Å; F101-F418 HydrophobicContact CZ-CE1 4.34Å
102M95.9Very high93Very high56 Ų5662.6 Ų62.628%0.27631%0.308SS..SBendtrans-104.9153.2-178.7-71.5-176.7177.300111.7F94 E98 M99 Q106 I107 K110F94-M102 HydrophobicContact CD2-SD 4.44Å; F94-M102 HydrophobicContact CE2-SD 3.81Å; E98-M102 HydrophobicContact CB-CE 3.93Å; E98-M102 WeakPolarHBondContact OE2-CE 3.41Å; M99-M102 PolarHBondContact O-N 2.87Å; M102-Q106 HydrophobicContact CB-CB 4.1Å; M102-Q106 HydrophobicContact CG-CB 4.41Å; M102-Q106 HydrophobicContact SD-CB 4.32Å; M102-I107 HydrophobicContact CB-CD1 4.3Å; M102-I107 HydrophobicContact CB-CG1 3.66Å; M102-K110 HydrophobicContact CE-CD 4.32Å
103N95.5Very high92.9Very high79 Ų7966.1 Ų66.142%0.42233%0.327SS..  trans-77.9160169.473.264.6000111.1F105 Q106 I107N103-F105 VanDerWaalsContact C-N 3.27Å; N103-F105 PolarHBondContact O-N 3.45Å; N103-F105 VanDerWaalsContact O-N 3.14Å; N103-F105 WeakPolarHBondContact OD1-CB 3.28Å; N103-F105 PolarHBondContact OD1-N 2.91Å; N103-Q106 VanDerWaalsContact N-OE1 3.15Å; N103-Q106 PolarHBondContact ND2-OE1 3.21Å; N103-Q106 PolarHBondContact O-N 3.49Å; N103-Q106 VanDerWaalsContact O-N 3.1Å; N103-Q106 PolarHBondContact OD1-N 3.37Å; N103-Q106 VanDerWaalsContact OD1-N 3.13Å; N103-I107 WeakPolarHBondContact O-CG1 3.36Å; N103-I107 PolarHBondContact O-N 3.28Å; N103-I107 VanDerWaalsContact O-N 3.09Å
104P90.3Very high92.7Very high97 Ų9762.6 Ų62.663%0.6331%0.311SS*.Hα-helixtrans-53.8-38.9-176.2-29.736.4000114.6I107 Y108P104-I107 PolarHBondContact O-N 3.01Å; P104-Y108 VanDerWaalsContact O-CD2 3.3Å; P104-Y108 WeakPolarHBondContact O-CD2 3.18Å; P104-Y108 PolarHBondContact O-N 2.81Å
105F91.1Very high92.4Very high145 Ų14564.7 Ų64.764%0.63633%0.325SS*.Hα-helixtrans-65.5-42.9-179.8177.8-99.2000112.1N103 Y108 M109N103-F105 VanDerWaalsContact C-N 3.27Å; N103-F105 PolarHBondContact O-N 3.45Å; N103-F105 VanDerWaalsContact O-N 3.14Å; N103-F105 WeakPolarHBondContact OD1-CB 3.28Å; N103-F105 PolarHBondContact OD1-N 2.91Å; F105-Y108 PolarHBondContact O-N 2.98Å; F105-M109 HydrophobicContact CD1-CG 4.3Å; F105-M109 HydrophobicContact CE1-CG 3.84Å; F105-M109 HydrophobicContact CE2-CG 4.15Å; F105-M109 HydrophobicContact CE2-SD 4.42Å; F105-M109 HydrophobicContact CZ-CG 3.75Å; F105-M109 HydrophobicContact CZ-SD 4.15Å; F105-M109 WeakPolarHBondContact O-CG 3.24Å; F105-M109 PolarHBondContact O-N 2.84Å
106Q94.3Very high92.1Very high93 Ų9367.9 Ų67.944%0.43534%0.337SS..Hα-helixtrans-61.9-43.6175.1-72171.9-34.100111.7M102 N103 Y108 M109 K110M102-Q106 HydrophobicContact CB-CB 4.1Å; M102-Q106 HydrophobicContact CG-CB 4.41Å; M102-Q106 HydrophobicContact SD-CB 4.32Å; N103-Q106 VanDerWaalsContact N-OE1 3.15Å; N103-Q106 PolarHBondContact ND2-OE1 3.21Å; N103-Q106 PolarHBondContact O-N 3.49Å; N103-Q106 VanDerWaalsContact O-N 3.1Å; N103-Q106 PolarHBondContact OD1-N 3.37Å; N103-Q106 VanDerWaalsContact OD1-N 3.13Å; Q106-Y108 VanDerWaalsContact C-N 3.34Å; Q106-Y108 PolarHBondContact O-N 2.75Å; Q106-M109 PolarHBondContact O-N 3.49Å; Q106-K110 WeakPolarHBondContact O-CB 3.47Å; Q106-K110 PolarHBondContact O-N 2.85Å
107I92.3Very high91.8Very high42 Ų4270.8 Ų70.822%0.21535%0.353CS..Hα-helixtrans-57.9-48.8176.4-64.1170.8000109.9F94 M99 M102 N103 P104 K110 A111F94-I107 HydrophobicContact CZ-CG2 4.19Å; M99-I107 HydrophobicContact CE-CG2 4.39Å; M99-I107 HydrophobicContact CG-CD1 3.84Å; M99-I107 HydrophobicContact CG-CG1 3.98Å; M99-I107 HydrophobicContact CG-CG2 4.02Å; M99-I107 WeakPolarHBondContact O-CD1 3.25Å; M99-I107 HydrophobicContact SD-CG2 4.36Å; M102-I107 HydrophobicContact CB-CD1 4.3Å; M102-I107 HydrophobicContact CB-CG1 3.66Å; N103-I107 WeakPolarHBondContact O-CG1 3.36Å; N103-I107 PolarHBondContact O-N 3.28Å; N103-I107 VanDerWaalsContact O-N 3.09Å; P104-I107 PolarHBondContact O-N 3.01Å; I107-K110 PolarHBondContact O-N 3.35Å; I107-A111 WeakPolarHBondContact O-CB 3.24Å; I107-A111 PolarHBondContact O-N 3.29Å
108Y89.9Confident91.5Very high69 Ų6971.2 Ų71.227%0.27136%0.358SS..Hα-helixtrans-61.3-47179-94.7-81.6000112.6P104 F105 Q106 K110 A111 I112 L218 Q219P104-Y108 VanDerWaalsContact O-CD2 3.3Å; P104-Y108 WeakPolarHBondContact O-CD2 3.18Å; P104-Y108 PolarHBondContact O-N 2.81Å; F105-Y108 PolarHBondContact O-N 2.98Å; Q106-Y108 VanDerWaalsContact C-N 3.34Å; Q106-Y108 PolarHBondContact O-N 2.75Å; Y108-K110 PolarHBondContact O-N 3Å; Y108-A111 PolarHBondContact O-N 3.14Å; Y108-I112 VanDerWaalsContact O-CG1 3.3Å; Y108-I112 WeakPolarHBondContact O-CG1 3.39Å; Y108-I112 PolarHBondContact O-N 3.4Å; Y108-L218 HydrophobicContact CE1-CD2 3.97Å; Y108-L218 HydrophobicContact CE1-CG 4.48Å; Y108-L218 HydrophobicContact CE2-CD2 4.3Å; Y108-Q219 PolarHBondContact OH-NE2 2.51Å
109M90.9Very high91.3Very high104 Ų10469.7 Ų69.751%0.51235%0.351SS..Hα-helixtrans-61.4-44.9179.7-74.1-59.7-60.700111.9F105 Q106 I112 D113F105-M109 HydrophobicContact CD1-CG 4.3Å; F105-M109 HydrophobicContact CE1-CG 3.84Å; F105-M109 HydrophobicContact CE2-CG 4.15Å; F105-M109 HydrophobicContact CE2-SD 4.42Å; F105-M109 HydrophobicContact CZ-CG 3.75Å; F105-M109 HydrophobicContact CZ-SD 4.15Å; F105-M109 WeakPolarHBondContact O-CG 3.24Å; F105-M109 PolarHBondContact O-N 2.84Å; Q106-M109 PolarHBondContact O-N 3.49Å; M109-I112 PolarHBondContact O-N 3.44Å; M109-D113 PolarHBondContact O-N 3Å; M109-D113 VanDerWaalsContact O-N 3.14Å
110K92.6Very high91.1Very high66 Ų6671.1 Ų71.129%0.28736%0.36SS..Hα-helixtrans-68.3-38.7178-174153.9176.6171.90112.2F94 E98 M102 Q106 I107 Y108 I112 D113 L114F94-K110 HydrophobicContact CD1-CG 4.49Å; F94-K110 HydrophobicContact CD2-CB 4.47Å; F94-K110 HydrophobicContact CD2-CD 3.39Å; F94-K110 VanDerWaalsContact CD2-CE 3.41Å; F94-K110 HydrophobicContact CD2-CG 3.77Å; F94-K110 HydrophobicContact CE1-CG 4.39Å; F94-K110 HydrophobicContact CE2-CB 3.87Å; F94-K110 HydrophobicContact CE2-CD 3.58Å; F94-K110 HydrophobicContact CE2-CG 3.66Å; F94-K110 HydrophobicContact CG-CD 4.09Å; F94-K110 HydrophobicContact CG-CG 4.18Å; F94-K110 HydrophobicContact CZ-CB 3.96Å; F94-K110 HydrophobicContact CZ-CD 4.4Å; F94-K110 HydrophobicContact CZ-CG 3.98Å; E98-K110 IonicContact OE1-NZ 3.61Å; E98-K110 PolarHBondContact OE1-NZ 2.98Å; E98-K110 VanDerWaalsContact OE1-NZ 3.11Å; E98-K110 IonicContact OE2-NZ 2.82Å; E98-K110 PolarHBondContact OE2-NZ 3.13Å; M102-K110 HydrophobicContact CE-CD 4.32Å; Q106-K110 WeakPolarHBondContact O-CB 3.47Å; Q106-K110 PolarHBondContact O-N 2.85Å; I107-K110 PolarHBondContact O-N 3.35Å; Y108-K110 PolarHBondContact O-N 3Å; K110-I112 PolarHBondContact O-N 3.09Å; K110-D113 PolarHBondContact O-N 2.79Å; K110-L114 HydrophobicContact CG-CD1 4.23Å; K110-L114 WeakPolarHBondContact O-CG 3.29Å; K110-L114 PolarHBondContact O-N 3.25Å
111A89.9Confident90.9Very high35 Ų3568.7 Ų68.729%0.28935%0.347SS..Hα-helixtrans-63.2-40.3175.100000112.4I107 Y108 T115I107-A111 WeakPolarHBondContact O-CB 3.24Å; I107-A111 PolarHBondContact O-N 3.29Å; Y108-A111 PolarHBondContact O-N 3.14Å; A111-T115 VanDerWaalsContact O-CB 3.28Å; A111-T115 WeakPolarHBondContact O-CB 3.44Å; A111-T115 PolarHBondContact O-N 3.46Å; A111-T115 PolarHBondContact O-OG1 3Å
112I89.3Confident90.7Very high30 Ų3062.2 Ų62.215%0.15432%0.319CS..Hα-helixtrans-62.8-44.1175.3-71.1167.2000110.7Y108 M109 K110 T115 K116 V222 F226Y108-I112 VanDerWaalsContact O-CG1 3.3Å; Y108-I112 WeakPolarHBondContact O-CG1 3.39Å; Y108-I112 PolarHBondContact O-N 3.4Å; M109-I112 PolarHBondContact O-N 3.44Å; K110-I112 PolarHBondContact O-N 3.09Å; I112-T115 PolarHBondContact O-N 3.17Å; I112-K116 HydrophobicContact CG2-CD 4.22Å; I112-K116 WeakPolarHBondContact O-CG 3.45Å; I112-K116 PolarHBondContact O-N 2.8Å; I112-V222 HydrophobicContact CG1-CG1 4.36Å; I112-F226 HydrophobicContact CG2-CG 4.47Å
113D90.5Very high90.6Very high90 Ų9060.7 Ų60.748%0.48131%0.312SS..Hα-helixtrans-62.5-49.2179-171.965.8000112.2M109 K110 T115 K116 N117M109-D113 PolarHBondContact O-N 3Å; M109-D113 VanDerWaalsContact O-N 3.14Å; K110-D113 PolarHBondContact O-N 2.79Å; D113-T115 VanDerWaalsContact C-N 3.29Å; D113-T115 PolarHBondContact O-N 2.98Å; D113-K116 PolarHBondContact O-N 2.96Å; D113-N117 PolarHBondContact O-N 3.17Å; D113-N117 PolarHBondContact O-ND2 3.4Å
114L90.1Very high90.5Very high22 Ų2261.3 Ų61.312%0.11531%0.311CS..Hα-helixtrans-58.6-41.8175.2-70.9171.4000111.9D90 L91 F94 K110 N117 N118D90-L114 HydrophobicContact CB-CD2 4.3Å; L91-L114 HydrophobicContact CD1-CD1 4.13Å; F94-L114 HydrophobicContact CB-CD1 4.08Å; F94-L114 HydrophobicContact CD1-CD1 3.42Å; F94-L114 VanDerWaalsContact CD1-CD1 3.42Å; F94-L114 HydrophobicContact CE1-CD1 4.05Å; F94-L114 HydrophobicContact CG-CD1 3.9Å; K110-L114 HydrophobicContact CG-CD1 4.23Å; K110-L114 WeakPolarHBondContact O-CG 3.29Å; K110-L114 PolarHBondContact O-N 3.25Å; L114-N117 PolarHBondContact O-N 2.99Å; L114-N118 WeakPolarHBondContact O-CB 3.2Å; L114-N118 PolarHBondContact O-N 3.43Å
115T87.5Confident90.7Very high48 Ų4856.9 Ų56.929%0.29428%0.281SS..Hα-helixtrans-65.2-40.2178.8-59.20000111.7A111 I112 D113 N118 M119 M227A111-T115 VanDerWaalsContact O-CB 3.28Å; A111-T115 WeakPolarHBondContact O-CB 3.44Å; A111-T115 PolarHBondContact O-N 3.46Å; A111-T115 PolarHBondContact O-OG1 3Å; I112-T115 PolarHBondContact O-N 3.17Å; D113-T115 VanDerWaalsContact C-N 3.29Å; D113-T115 PolarHBondContact O-N 2.98Å; T115-N118 PolarHBondContact O-N 2.99Å; T115-M119 WeakPolarHBondContact O-CB 3.41Å; T115-M119 PolarHBondContact O-N 2.55Å; T115-M227 HydrophobicContact CG2-CE 3.62Å; T115-M227 HydrophobicContact CG2-CG 3.8Å; T115-M227 HydrophobicContact CG2-SD 3.83Å
116K88.3Confident90.8Very high79 Ų7950 Ų5034%0.34325%0.251SS..Hα-helixtrans-63-45175.3-76.6175.1177.7178.70111.9I112 D113 N118 M119 N120I112-K116 HydrophobicContact CG2-CD 4.22Å; I112-K116 WeakPolarHBondContact O-CG 3.45Å; I112-K116 PolarHBondContact O-N 2.8Å; D113-K116 PolarHBondContact O-N 2.96Å; K116-N118 VanDerWaalsContact C-N 3.33Å; K116-N118 PolarHBondContact O-N 3.38Å; K116-M119 PolarHBondContact O-N 2.76Å; K116-N120 PolarHBondContact O-N 2.95Å; K116-N120 PolarHBondContact O-ND2 3.26Å
117N87.4Confident90.9Very high71 Ų7148.2 Ų48.238%0.3825%0.245SC..Hα-helixtrans-61.5-43.4176.9-69-29.3000111.3D113 L114 N120 M121D113-N117 PolarHBondContact O-N 3.17Å; D113-N117 PolarHBondContact O-ND2 3.4Å; L114-N117 PolarHBondContact O-N 2.99Å; N117-N120 PolarHBondContact O-N 2.65Å; N117-M121 PolarHBondContact O-N 2.79Å; N117-M121 VanDerWaalsContact O-N 3.14Å
118N88.5Confident91.1Very high60 Ų6046.7 Ų46.732%0.32124%0.239SC..Hα-helixtrans-64.2-38.8174.8-17565.6000112.9L114 T115 K116 M121 S122L114-N118 WeakPolarHBondContact O-CB 3.2Å; L114-N118 PolarHBondContact O-N 3.43Å; T115-N118 PolarHBondContact O-N 2.99Å; K116-N118 VanDerWaalsContact C-N 3.33Å; K116-N118 PolarHBondContact O-N 3.38Å; N118-M121 PolarHBondContact O-N 2.83Å; N118-M121 WeakPolarHBondContact OD1-CE 3.46Å; N118-S122 WeakPolarHBondContact O-CB 3.41Å; N118-S122 PolarHBondContact O-N 3.04Å; N118-S122 PolarHBondContact O-OG 3.42Å
119M89.5Confident91.4Very high18 Ų1843.4 Ų43.49%0.08923%0.227CC..Hα-helixtrans-66.2-45.9177.5-171.66176.400111.6T115 K116 M121 S122 L123 M227 I231T115-M119 WeakPolarHBondContact O-CB 3.41Å; T115-M119 PolarHBondContact O-N 2.55Å; K116-M119 PolarHBondContact O-N 2.76Å; M119-M121 VanDerWaalsContact C-N 3.28Å; M119-M121 PolarHBondContact O-N 2.8Å; M119-S122 WeakPolarHBondContact O-CA 3.48Å; M119-S122 WeakPolarHBondContact O-CB 3.3Å; M119-S122 PolarHBondContact O-N 3.32Å; M119-L123 WeakPolarHBondContact O-CG 3.28Å; M119-L123 PolarHBondContact O-N 3.34Å; M119-M227 HydrophobicContact CE-CB 4.18Å; M119-M227 HydrophobicContact CE-CE 4.38Å; M119-I231 HydrophobicContact CE-CD1 3.52Å; M119-I231 HydrophobicContact CE-CG1 4.04Å; M119-I231 HydrophobicContact SD-CD1 3.68Å; M119-I231 HydrophobicContact SD-CG1 3.69Å
120N89.6Confident91.7Very high87 Ų8739.1 Ų39.147%0.46521%0.206SC..Hα-helixtrans-57.3-42.9176.4-73.8-22.3000111.6K116 N117 L123 K124K116-N120 PolarHBondContact O-N 2.95Å; K116-N120 PolarHBondContact O-ND2 3.26Å; N117-N120 PolarHBondContact O-N 2.65Å; N120-L123 PolarHBondContact O-N 3.1Å; N120-K124 PolarHBondContact O-N 3.15Å
121M90.4Very high91.8Very high13 Ų1341 Ų416%0.06421%0.214CC..Hα-helixtrans-63.2-44.1173.3-179.4-179.666.700111.9V79 I84 I87 N117 N118 M119 L123 K124 F125V79-M121 HydrophobicContact CG1-CG 4.17Å; V79-M121 HydrophobicContact CG1-SD 4.3Å; V79-M121 HydrophobicContact CG2-CG 4.29Å; I84-M121 HydrophobicContact CB-SD 4.21Å; I84-M121 HydrophobicContact CG1-SD 3.61Å; I84-M121 HydrophobicContact CG2-CE 4.4Å; I84-M121 HydrophobicContact CG2-SD 4.36Å; I87-M121 HydrophobicContact CD1-CB 4.25Å; I87-M121 HydrophobicContact CD1-CE 4.15Å; I87-M121 HydrophobicContact CD1-SD 3.68Å; N117-M121 PolarHBondContact O-N 2.79Å; N117-M121 VanDerWaalsContact O-N 3.14Å; N118-M121 PolarHBondContact O-N 2.83Å; N118-M121 WeakPolarHBondContact OD1-CE 3.46Å; M119-M121 VanDerWaalsContact C-N 3.28Å; M119-M121 PolarHBondContact O-N 2.8Å; M121-L123 VanDerWaalsContact C-N 3.28Å; M121-L123 PolarHBondContact O-N 3.04Å; M121-K124 WeakPolarHBondContact O-CB 3.12Å; M121-K124 PolarHBondContact O-N 3.12Å; M121-K124 VanDerWaalsContact O-N 3.09Å; M121-F125 HydrophobicContact CG-CD2 4.33Å; M121-F125 HydrophobicContact CG-CE2 4.06Å; M121-F125 WeakPolarHBondContact O-CD2 3.03Å; M121-F125 PolarHBondContact O-N 2.95Å; M121-F125 VanDerWaalsContact O-N 3.17Å
122S91.8Very high92.1Very high3 Ų341.2 Ų41.22%0.02121%0.214CC..Hα-helixtrans-61.7-35.6179.7-61.40000112.6N118 M119 F125 L126N118-S122 WeakPolarHBondContact O-CB 3.41Å; N118-S122 PolarHBondContact O-N 3.04Å; N118-S122 PolarHBondContact O-OG 3.42Å; M119-S122 WeakPolarHBondContact O-CA 3.48Å; M119-S122 WeakPolarHBondContact O-CB 3.3Å; M119-S122 PolarHBondContact O-N 3.32Å; S122-F125 WeakPolarHBondContact O-CB 3.13Å; S122-F125 PolarHBondContact O-N 3.28Å; S122-L126 PolarHBondContact O-N 3.49Å
123L93.1Very high92.4Very high23 Ų2348.2 Ų48.212%0.1225%0.246CC..Hα-helixtrans-67.8-33.5174.3-66.8178.9000112.6M119 N120 M121 F125 L126 D127 D230 Y234M119-L123 WeakPolarHBondContact O-CG 3.28Å; M119-L123 PolarHBondContact O-N 3.34Å; N120-L123 PolarHBondContact O-N 3.1Å; M121-L123 VanDerWaalsContact C-N 3.28Å; M121-L123 PolarHBondContact O-N 3.04Å; L123-F125 VanDerWaalsContact C-N 3.35Å; L123-L126 HydrophobicContact CD2-CD2 4.45Å; L123-L126 WeakPolarHBondContact O-CB 3.38Å; L123-L126 PolarHBondContact O-N 2.93Å; L123-D127 PolarHBondContact O-N 2.74Å; L123-D230 HydrophobicContact CD1-CB 4.36Å; L123-Y234 HydrophobicContact CB-CD2 4.49Å; L123-Y234 HydrophobicContact CD2-CD2 3.93Å; L123-Y234 HydrophobicContact CD2-CE2 4.47Å; L123-Y234 HydrophobicContact CD2-CG 3.98Å
124K93.1Very high92.7Very high93 Ų9347.5 Ų47.540%0.40425%0.252SS..Hα-helixtrans-66.5-36172.8-67.6-177.7170-158.60112.7V79 N120 M121 L126 D127V79-K124 HydrophobicContact CG2-CB 3.74Å; V79-K124 HydrophobicContact CG2-CD 3.58Å; V79-K124 HydrophobicContact CG2-CG 4.35Å; N120-K124 PolarHBondContact O-N 3.15Å; M121-K124 WeakPolarHBondContact O-CB 3.12Å; M121-K124 PolarHBondContact O-N 3.12Å; M121-K124 VanDerWaalsContact O-N 3.09Å; K124-L126 VanDerWaalsContact C-N 3.3Å; K124-D127 PolarHBondContact O-N 3.27Å
125F93.9Very high93Very high3 Ų347.2 Ų47.21%0.01325%0.251CS..Hα-helixtrans-64.4-42172.2-83.5-130.1000110.6Y28 P56 A58 F75 V77 V79 I84 M121 S122 L123 D127 G128Y28-F125 HydrophobicContact CD2-CD1 4.31Å; Y28-F125 HydrophobicContact CE2-CB 4.34Å; Y28-F125 AromaticContact CE2-CD1 3.61Å; Y28-F125 HydrophobicContact CE2-CD1 3.61Å; Y28-F125 HydrophobicContact CE2-CE1 4.42Å; Y28-F125 HydrophobicContact CE2-CG 4.44Å; Y28-F125 VanDerWaalsContact OH-CB 3.3Å; Y28-F125 WeakPolarHBondContact OH-CB 3.09Å; P56-F125 HydrophobicContact CB-CD1 3.7Å; P56-F125 HydrophobicContact CB-CE1 3.47Å; P56-F125 VanDerWaalsContact CB-CE1 3.47Å; P56-F125 HydrophobicContact CB-CZ 4.35Å; P56-F125 HydrophobicContact CG-CD1 3.94Å; P56-F125 HydrophobicContact CG-CE1 3.52Å; A58-F125 HydrophobicContact CB-CZ 4.33Å; F75-F125 WeakPolarHBondContact CE2-O 3.24Å; V77-F125 HydrophobicContact CB-CD2 4.4Å; V77-F125 HydrophobicContact CG1-CB 4.39Å; V77-F125 HydrophobicContact CG1-CD1 4.35Å; V77-F125 HydrophobicContact CG1-CD2 4.36Å; V77-F125 HydrophobicContact CG1-CG 4.12Å; V77-F125 HydrophobicContact CG2-CE2 4.24Å; V77-F125 HydrophobicContact CG2-CZ 4.39Å; V79-F125 HydrophobicContact CB-CE2 3.91Å; V79-F125 HydrophobicContact CG1-CE2 4.13Å; V79-F125 HydrophobicContact CG2-CD2 4.16Å; V79-F125 HydrophobicContact CG2-CE2 3.99Å; I84-F125 HydrophobicContact CD1-CE2 4.12Å; I84-F125 HydrophobicContact CD1-CZ 3.56Å; I84-F125 HydrophobicContact CG1-CE2 4.45Å; I84-F125 HydrophobicContact CG1-CZ 4.25Å; M121-F125 HydrophobicContact CG-CD2 4.33Å; M121-F125 HydrophobicContact CG-CE2 4.06Å; M121-F125 WeakPolarHBondContact O-CD2 3.03Å; M121-F125 PolarHBondContact O-N 2.95Å; M121-F125 VanDerWaalsContact O-N 3.17Å; S122-F125 WeakPolarHBondContact O-CB 3.13Å; S122-F125 PolarHBondContact O-N 3.28Å; L123-F125 VanDerWaalsContact C-N 3.35Å; F125-D127 VanDerWaalsContact C-N 3.29Å; F125-D127 PolarHBondContact O-N 3.26Å; F125-G128 PolarHBondContact O-N 2.94Å; F125-G128 VanDerWaalsContact O-N 3.14Å
126L95Very high93.5Very high0 Ų045.5 Ų45.50%024%0.24CC..Hα-helixtrans-60.6-39.7178.4-17450.2000111.8W27 S122 L123 K124 G128 V129 V130 G155 Y234 Y235W27-L126 HydrophobicContact CH2-CD1 4.08Å; W27-L126 HydrophobicContact CZ2-CD1 3.98Å; S122-L126 PolarHBondContact O-N 3.49Å; L123-L126 HydrophobicContact CD2-CD2 4.45Å; L123-L126 WeakPolarHBondContact O-CB 3.38Å; L123-L126 PolarHBondContact O-N 2.93Å; K124-L126 VanDerWaalsContact C-N 3.3Å; L126-G128 VanDerWaalsContact C-N 3.26Å; L126-G128 PolarHBondContact O-N 3.29Å; L126-V129 CarbonylContact O-C 3.54Å; L126-V129 PolarHBondContact O-N 3.5Å; L126-V130 HydrophobicContact CD1-CB 4.35Å; L126-V130 HydrophobicContact CD1-CG1 3.6Å; L126-V130 HydrophobicContact CD1-CG2 3.86Å; L126-V130 HydrophobicContact CG-CG1 4.45Å; L126-V130 HydrophobicContact CG-CG2 3.79Å; L126-V130 WeakPolarHBondContact O-CG2 3.4Å; L126-V130 PolarHBondContact O-N 3.3Å; L126-G155 VanDerWaalsContact CD1-CA 3.48Å; L126-Y234 HydrophobicContact CD2-CD1 3.81Å; L126-Y234 HydrophobicContact CD2-CE1 3.4Å; L126-Y234 VanDerWaalsContact CD2-CE1 3.4Å; L126-Y234 HydrophobicContact CG-CE1 3.67Å; L126-Y235 HydrophobicContact CD2-CE1 3.99Å
127D95.8Very high93.9Very high56 Ų5648 Ų4830%0.29925%0.25SS..Iπ-helixtrans-54.3-41.8174.4-74.4-18.8000112.5L123 K124 F125 V129 K131 S132 Y234L123-D127 PolarHBondContact O-N 2.74Å; K124-D127 PolarHBondContact O-N 3.27Å; F125-D127 VanDerWaalsContact C-N 3.29Å; F125-D127 PolarHBondContact O-N 3.26Å; D127-V129 PolarHBondContact O-N 3.15Å; D127-V129 VanDerWaalsContact O-N 3.13Å; D127-K131 HydrophobicContact CB-CB 4.5Å; D127-K131 HydrophobicContact CB-CD 4.47Å; D127-K131 WeakPolarHBondContact O-CB 3.21Å; D127-K131 PolarHBondContact O-N 3.11Å; D127-K131 VanDerWaalsContact O-N 3.12Å; D127-K131 WeakPolarHBondContact OD1-CD 3.34Å; D127-K131 WeakPolarHBondContact OD1-CE 3.38Å; D127-K131 IonicContact OD1-NZ 3.78Å; D127-K131 PolarHBondContact OD1-NZ 3.03Å; D127-K131 IonicContact OD2-NZ 3.93Å; D127-S132 PolarHBondContact O-N 2.78Å; D127-Y234 PolarHBondContact N-OH 2.92Å; D127-Y234 WeakPolarHBondContact OD1-CE2 3.35Å; D127-Y234 VanDerWaalsContact OD1-CZ 3.23Å; D127-Y234 PolarHBondContact OD1-OH 2.94Å
128G95.9Very high94.4Very high10 Ų1049.1 Ų49.110%0.10325%0.252CS..Iπ-helixtrans-60.9-20.2177.500000114.3D76 F125 L126 S132D76-G128 VanDerWaalsContact O-CA 3.28Å; D76-G128 WeakPolarHBondContact O-CA 3.48Å; F125-G128 PolarHBondContact O-N 2.94Å; F125-G128 VanDerWaalsContact O-N 3.14Å; L126-G128 VanDerWaalsContact C-N 3.26Å; L126-G128 PolarHBondContact O-N 3.29Å; G128-S132 WeakPolarHBondContact O-CB 3.04Å
129V96.6Very high94.9Very high0 Ų046.3 Ų46.30%024%0.237CC..Iπ-helixtrans-101.4-66174.4-1740000111W27 Y28 L54 F75 L126 D127 M135 M136 L139W27-V129 HydrophobicContact CH2-CB 4.07Å; W27-V129 HydrophobicContact CH2-CG1 3.82Å; W27-V129 HydrophobicContact CH2-CG2 4.18Å; W27-V129 HydrophobicContact CZ3-CG1 3.95Å; Y28-V129 HydrophobicContact CE1-CG2 4.44Å; L54-V129 HydrophobicContact CD1-CG1 4.27Å; L54-V129 HydrophobicContact CD1-CG2 4.38Å; F75-V129 HydrophobicContact CD1-CG2 4.1Å; F75-V129 HydrophobicContact CD2-CG2 3.76Å; F75-V129 HydrophobicContact CE1-CG2 4.03Å; F75-V129 HydrophobicContact CE2-CG2 3.67Å; F75-V129 HydrophobicContact CG-CG2 3.97Å; F75-V129 HydrophobicContact CZ-CG2 3.82Å; L126-V129 CarbonylContact O-C 3.54Å; L126-V129 PolarHBondContact O-N 3.5Å; D127-V129 PolarHBondContact O-N 3.15Å; D127-V129 VanDerWaalsContact O-N 3.13Å; V129-M135 HydrophobicContact CG1-CG 4.23Å; V129-M136 HydrophobicContact CG1-SD 4.4Å; V129-M136 VanDerWaalsContact O-CG 3.24Å; V129-M136 WeakPolarHBondContact O-CG 3.47Å; V129-L139 HydrophobicContact CG1-CD1 3.89Å
130V96.2Very high95.2Very high14 Ų1451.3 Ų51.39%0.08526%0.258CS..Iπ-helixtrans-82-25.2-165.5-58.60000114.3L126 M136 L158 T159 Y234 V238L126-V130 HydrophobicContact CD1-CB 4.35Å; L126-V130 HydrophobicContact CD1-CG1 3.6Å; L126-V130 HydrophobicContact CD1-CG2 3.86Å; L126-V130 HydrophobicContact CG-CG1 4.45Å; L126-V130 HydrophobicContact CG-CG2 3.79Å; L126-V130 WeakPolarHBondContact O-CG2 3.4Å; L126-V130 PolarHBondContact O-N 3.3Å; V130-M136 HydrophobicContact CG1-SD 4.44Å; V130-L158 HydrophobicContact CG1-CD2 4.47Å; V130-T159 WeakPolarHBondContact CG1-OG1 3.26Å; V130-Y234 HydrophobicContact CG2-CE1 3.76Å; V130-Y234 WeakPolarHBondContact CG2-OH 3.32Å; V130-V238 HydrophobicContact CG2-CG2 4.22Å
131K95.3Very high95.6Very high105 Ų10552.8 Ų52.846%0.45726%0.262SS..Iπ-helixtrans-95.2-10.2174-64-169.5-170.8148.30112.8D127 E133D127-K131 HydrophobicContact CB-CB 4.5Å; D127-K131 HydrophobicContact CB-CD 4.47Å; D127-K131 WeakPolarHBondContact O-CB 3.21Å; D127-K131 PolarHBondContact O-N 3.11Å; D127-K131 VanDerWaalsContact O-N 3.12Å; D127-K131 WeakPolarHBondContact OD1-CD 3.34Å; D127-K131 WeakPolarHBondContact OD1-CE 3.38Å; D127-K131 IonicContact OD1-NZ 3.78Å; D127-K131 PolarHBondContact OD1-NZ 3.03Å; D127-K131 IonicContact OD2-NZ 3.93Å; K131-E133 PolarHBondContact O-N 3.18Å
132S96.8Very high95.8Very high40 Ų4053 Ų5328%0.2827%0.268SS..  trans-77.2107.2172.71750000110.4D127 G128 A134 M135 M136D127-S132 PolarHBondContact O-N 2.78Å; G128-S132 WeakPolarHBondContact O-CB 3.04Å; S132-A134 VanDerWaalsContact C-N 3.27Å; S132-A134 PolarHBondContact O-N 3.18Å; S132-M135 PolarHBondContact O-N 2.94Å; S132-M135 WeakPolarHBondContact OG-CB 3.38Å; S132-M135 PolarHBondContact OG-N 3.23Å; S132-M136 WeakPolarHBondContact O-CB 3.41Å; S132-M136 PolarHBondContact O-N 2.85Å
133E95.4Very high96Very high177 Ų17758.4 Ų58.483%0.82730%0.296SS*.Hα-helixtrans-57.5-42.1177.6-68.4-173.2174.400112K131 K137K131-E133 PolarHBondContact O-N 3.18Å; E133-K137 WeakPolarHBondContact O-CB 3.39Å; E133-K137 PolarHBondContact O-N 2.9Å
134A96.8Very high96.2Very high75 Ų7558.7 Ų58.762%0.6230%0.296SS*.Hα-helixtrans-63.1-46.9179.100000111.6S132 K138S132-A134 VanDerWaalsContact C-N 3.27Å; S132-A134 PolarHBondContact O-N 3.18Å; A134-K138 WeakPolarHBondContact O-CB 3.5Å; A134-K138 PolarHBondContact O-N 3.23Å; A134-K138 VanDerWaalsContact O-N 3.08Å
135M97.3Very high96.5Very high16 Ų1657.7 Ų57.78%0.07930%0.295CS..Hα-helixtrans-66.4-50.5179.2-175.553.357.600111L54 E73 P74 F75 V129 S132 K137 K138 L139L54-M135 HydrophobicContact CD2-SD 4.29Å; E73-M135 HydrophobicContact CG-CE 4.32Å; E73-M135 HydrophobicContact CG-SD 4.22Å; P74-M135 WeakPolarHBondContact O-CE 3.43Å; F75-M135 HydrophobicContact CB-CE 3.65Å; V129-M135 HydrophobicContact CG1-CG 4.23Å; S132-M135 PolarHBondContact O-N 2.94Å; S132-M135 WeakPolarHBondContact OG-CB 3.38Å; S132-M135 PolarHBondContact OG-N 3.23Å; M135-K137 VanDerWaalsContact C-N 3.3Å; M135-K137 PolarHBondContact O-N 3.06Å; M135-K138 WeakPolarHBondContact O-CB 3.43Å; M135-K138 PolarHBondContact O-N 2.87Å; M135-K138 VanDerWaalsContact O-N 3.12Å; M135-L139 HydrophobicContact CG-CD1 4.22Å; M135-L139 HydrophobicContact CG-CG 4.39Å; M135-L139 WeakPolarHBondContact O-CG 3.42Å; M135-L139 PolarHBondContact O-N 3.05Å; M135-L139 HydrophobicContact SD-CD1 4.4Å; M135-L139 HydrophobicContact SD-CD2 4.33Å; M135-L139 HydrophobicContact SD-CG 4.13Å
136M97.1Very high96.7Very high13 Ų1357.6 Ų57.66%0.06430%0.295CS..Hα-helixtrans-62.2-36.4179.6-76.6-50.5-55.500113.2V129 V130 S132 L139 K140 I162 L163V129-M136 HydrophobicContact CG1-SD 4.4Å; V129-M136 VanDerWaalsContact O-CG 3.24Å; V129-M136 WeakPolarHBondContact O-CG 3.47Å; V130-M136 HydrophobicContact CG1-SD 4.44Å; S132-M136 WeakPolarHBondContact O-CB 3.41Å; S132-M136 PolarHBondContact O-N 2.85Å; M136-L139 PolarHBondContact O-N 3.01Å; M136-L139 HydrophobicContact SD-CD1 4.24Å; M136-K140 WeakPolarHBondContact O-CB 3.43Å; M136-K140 VanDerWaalsContact O-CG 3.27Å; M136-K140 WeakPolarHBondContact O-CG 3.47Å; M136-K140 PolarHBondContact O-N 3.22Å; M136-I162 HydrophobicContact CE-CB 4.26Å; M136-I162 HydrophobicContact CE-CG2 3.52Å; M136-L163 HydrophobicContact CE-CD2 4.23Å
137K97.3Very high96.9Very high130 Ų13057.6 Ų57.657%0.56530%0.295SS*.Hα-helixtrans-60.9-49.7173-179.1179.8175.1-177.60110.6E133 M135 L139 K140 E141E133-K137 WeakPolarHBondContact O-CB 3.39Å; E133-K137 PolarHBondContact O-N 2.9Å; M135-K137 VanDerWaalsContact C-N 3.3Å; M135-K137 PolarHBondContact O-N 3.06Å; K137-L139 VanDerWaalsContact C-N 3.32Å; K137-L139 PolarHBondContact O-N 3.33Å; K137-K140 PolarHBondContact O-N 3.01Å; K137-E141 WeakPolarHBondContact CE-OE1 3.49Å; K137-E141 WeakPolarHBondContact CG-OE1 3.34Å; K137-E141 WeakPolarHBondContact O-CG 3.35Å; K137-E141 PolarHBondContact O-N 2.91Å
138K97.4Very high97Very high95 Ų9555 Ų5541%0.41328%0.281SS..Hα-helixtrans-59.8-41.5178.3-172.2172.4-177.9178.90112.2E73 A134 M135 E141 G142E73-K138 WeakPolarHBondContact OE1-CD 3.23Å; E73-K138 VanDerWaalsContact OE1-CE 3.24Å; E73-K138 WeakPolarHBondContact OE1-CE 3.36Å; E73-K138 IonicContact OE1-NZ 2.61Å; E73-K138 PolarHBondContact OE1-NZ 3.16Å; E73-K138 WeakPolarHBondContact OE2-CE 3.29Å; E73-K138 IonicContact OE2-NZ 2.73Å; E73-K138 PolarHBondContact OE2-NZ 3.2Å; A134-K138 WeakPolarHBondContact O-CB 3.5Å; A134-K138 PolarHBondContact O-N 3.23Å; A134-K138 VanDerWaalsContact O-N 3.08Å; M135-K138 WeakPolarHBondContact O-CB 3.43Å; M135-K138 PolarHBondContact O-N 2.87Å; M135-K138 VanDerWaalsContact O-N 3.12Å; K138-E141 PolarHBondContact O-N 2.7Å; K138-G142 PolarHBondContact O-N 2.57Å
139L97.9Very high97.1Very high2 Ų254.5 Ų54.51%0.0128%0.276CS..Hα-helixtrans-65.6-39.8177.3-66.1-177.2000112.7L25 L54 V129 M135 M136 K137 G142 Y144 T159 L163L25-L139 HydrophobicContact CD1-CD2 3.95Å; L25-L139 HydrophobicContact CD2-CD2 4.16Å; L54-L139 HydrophobicContact CD2-CD2 4.13Å; V129-L139 HydrophobicContact CG1-CD1 3.89Å; M135-L139 HydrophobicContact CG-CD1 4.22Å; M135-L139 HydrophobicContact CG-CG 4.39Å; M135-L139 WeakPolarHBondContact O-CG 3.42Å; M135-L139 PolarHBondContact O-N 3.05Å; M135-L139 HydrophobicContact SD-CD1 4.4Å; M135-L139 HydrophobicContact SD-CD2 4.33Å; M135-L139 HydrophobicContact SD-CG 4.13Å; M136-L139 PolarHBondContact O-N 3.01Å; M136-L139 HydrophobicContact SD-CD1 4.24Å; K137-L139 VanDerWaalsContact C-N 3.32Å; K137-L139 PolarHBondContact O-N 3.33Å; L139-G142 PolarHBondContact O-N 3.06Å; L139-Y144 HydrophobicContact CD2-CE2 4.02Å; L139-T159 HydrophobicContact CD1-CG2 4.3Å; L139-L163 HydrophobicContact CB-CD1 4.29Å; L139-L163 HydrophobicContact CB-CD2 4.06Å
140K97.4Very high97.1Very high122 Ų12254.6 Ų54.653%0.5328%0.276SS..Hα-helixtrans-63.9-40.8174.3-73.4171.8-178.9178.30112.1M136 K137 G142 L163M136-K140 WeakPolarHBondContact O-CB 3.43Å; M136-K140 VanDerWaalsContact O-CG 3.27Å; M136-K140 WeakPolarHBondContact O-CG 3.47Å; M136-K140 PolarHBondContact O-N 3.22Å; K137-K140 PolarHBondContact O-N 3.01Å; K140-G142 VanDerWaalsContact C-N 3.26Å; K140-G142 PolarHBondContact O-N 2.55Å; K140-L163 HydrophobicContact CB-CD2 4.4Å; K140-L163 HydrophobicContact CG-CD2 3.68Å
141E97.1Very high97Very high119 Ų11954 Ų5456%0.55627%0.273SS*.Hα-helixtrans-72.3-19.1177.7-69.5171.4176.400112.9K137 K138 N143K137-E141 WeakPolarHBondContact CE-OE1 3.49Å; K137-E141 WeakPolarHBondContact CG-OE1 3.34Å; K137-E141 WeakPolarHBondContact O-CG 3.35Å; K137-E141 PolarHBondContact O-N 2.91Å; K138-E141 PolarHBondContact O-N 2.7Å; E141-N143 VanDerWaalsContact C-N 3.26Å; E141-N143 PolarHBondContact O-N 3.43Å; E141-N143 PolarHBondContact O-ND2 3.23Å
142G95.8Very high96.9Very high17 Ų1752.9 Ų52.918%0.17527%0.271CS..THydrogen-bonded Turntrans-62.4-27.1179.900000114.6K23 K138 L139 K140K23-G142 WeakPolarHBondContact CD-O 3.21Å; K23-G142 PolarHBondContact NZ-O 2.99Å; K138-G142 PolarHBondContact O-N 2.57Å; L139-G142 PolarHBondContact O-N 3.06Å; K140-G142 VanDerWaalsContact C-N 3.26Å; K140-G142 PolarHBondContact O-N 2.55Å
143N95.1Very high96.7Very high116 Ų11652.2 Ų52.262%0.6226%0.263SS*.  trans51.956-177.1-63.9-71.5000112.5K23 E141K23-N143 WeakPolarHBondContact CD-O 3.4Å; E141-N143 VanDerWaalsContact C-N 3.26Å; E141-N143 PolarHBondContact O-N 3.43Å; E141-N143 PolarHBondContact O-ND2 3.23Å
144Y98.1Very high96.6Very high29 Ų2944.5 Ų44.511%0.11423%0.228CC..  trans-73.5147.9178.7-60.4-76.1000111.9K23 L25 T52 L139 I165K23-Y144 HydrophobicContact CB-CD1 4.05Å; L25-Y144 HydrophobicContact CB-CD1 3.72Å; L25-Y144 HydrophobicContact CB-CD2 3.98Å; L25-Y144 HydrophobicContact CB-CE1 4.05Å; L25-Y144 HydrophobicContact CB-CE2 4.28Å; L25-Y144 HydrophobicContact CB-CG 3.68Å; L25-Y144 HydrophobicContact CD1-CE1 4.32Å; L25-Y144 HydrophobicContact CD1-CE2 4.11Å; L25-Y144 HydrophobicContact CD2-CD2 4.08Å; L25-Y144 HydrophobicContact CD2-CE2 4.19Å; L25-Y144 HydrophobicContact CG-CD2 4.45Å; L25-Y144 HydrophobicContact CG-CE2 4.43Å; T52-Y144 WeakPolarHBondContact CG2-OH 3.29Å; L139-Y144 HydrophobicContact CD2-CE2 4.02Å; Y144-I165 VanDerWaalsContact O-CG2 3.23Å; Y144-I165 WeakPolarHBondContact O-CG2 3.37Å
145D98.2Very high96.5Very high73 Ų7340.9 Ų40.939%0.3920%0.198SC..SBendtrans-93.9-22.8179.3-63.9-66.5000112.8G22 K23 P166 M467G22-D145 WeakPolarHBondContact CA-OD2 2.92Å; K23-D145 PolarHBondContact N-OD2 3.28Å; K23-D145 PolarHBondContact O-N 3.33Å; D145-P166 WeakPolarHBondContact O-CD 3.42Å; D145-M467 HydrophobicContact CB-CB 4.44Å; D145-M467 HydrophobicContact CB-CG 3.96Å; D145-M467 HydrophobicContact CB-SD 4.03Å
146V98.6Very high96.5Very high0 Ų040.2 Ų40.20%019%0.194CC..EExtended strand (participates in β ladder)trans-159.4147.1179.865.40000110.5I24 L25 P166 V168 I463 T466 M467I24-V146 HydrophobicContact CB-CG1 4.34Å; I24-V146 HydrophobicContact CG1-CG1 3.91Å; I24-V146 HydrophobicContact CG2-CG1 4.1Å; L25-V146 PolarHBondContact N-O 3.36Å; V146-P166 HydrophobicContact CG2-CB 4.32Å; V146-V168 HydrophobicContact CG2-CG2 3.86Å; V146-I463 HydrophobicContact CG1-CG2 4.18Å; V146-T466 HydrophobicContact CG2-CG2 4.12Å; V146-M467 HydrophobicContact CB-CG 3.75Å; V146-M467 HydrophobicContact CG1-CG 3.47Å; V146-M467 VanDerWaalsContact CG1-CG 3.47Å; V146-M467 HydrophobicContact CG1-SD 3.65Å
147L98.8Very high96.5Very high0 Ų039.8 Ų39.80%019%0.192CC..EExtended strand (participates in β ladder)trans-99.3126.2165.6-161.2151.9000109.6L25 W27 A149 Y156 T159 A160 I165 P166 L167 V168L25-L147 HydrophobicContact CD2-CD1 3.99Å; L25-L147 HydrophobicContact CD2-CG 4.46Å; L25-L147 HydrophobicContact CG-CD1 4.46Å; L25-L147 HydrophobicContact CG-CG 4.45Å; L25-L147 CarbonylContact O-C 3.56Å; L25-L147 WeakPolarHBondContact O-CA 3.15Å; W27-L147 HydrophobicContact CB-CD2 4.29Å; L147-A149 HydrophobicContact CD2-CB 3.76Å; L147-Y156 WeakPolarHBondContact CD1-O 3.27Å; L147-T159 HydrophobicContact CD1-CG2 4.23Å; L147-A160 HydrophobicContact CB-CB 4.16Å; L147-A160 HydrophobicContact CD1-CB 4.05Å; L147-I165 HydrophobicContact CB-CD1 3.89Å; L147-I165 HydrophobicContact CB-CG1 4.24Å; L147-P166 PolarHBondContact N-O 2.76Å; L147-L167 HydrophobicContact CB-CD1 4.13Å; L147-L167 HydrophobicContact CD2-CD1 3.57Å; L147-L167 HydrophobicContact CG-CD1 4.43Å; L147-V168 PolarHBondContact O-N 3.19Å
148F98.8Very high96.5Very high1 Ų133.6 Ų33.60%0.00417%0.166CC..EExtended strand (participates in β ladder)trans-111.5123.4173.8179.6-131000110.3I24 L25 V26 W27 M37 V40 L41 V168 L256 I463I24-F148 HydrophobicContact CG2-CB 4.19Å; L25-F148 PolarHBondContact O-N 3.42Å; V26-F148 VanDerWaalsContact CA-O 3.29Å; V26-F148 WeakPolarHBondContact CA-O 3.47Å; W27-F148 PolarHBondContact N-O 3.4Å; M37-F148 HydrophobicContact CE-CD1 3.44Å; M37-F148 VanDerWaalsContact CE-CD1 3.44Å; M37-F148 HydrophobicContact CE-CE1 3.31Å; M37-F148 HydrophobicContact CE-CG 4.14Å; M37-F148 HydrophobicContact CE-CZ 3.91Å; M37-F148 HydrophobicContact CG-CE1 4.38Å; V40-F148 HydrophobicContact CG1-CE1 4.2Å; V40-F148 HydrophobicContact CG1-CZ 4.4Å; L41-F148 HydrophobicContact CD2-CD1 3.83Å; L41-F148 HydrophobicContact CD2-CE1 4.05Å; F148-V168 WeakPolarHBondContact CA-O 3.5Å; F148-V168 HydrophobicContact CD2-CB 4.19Å; F148-V168 HydrophobicContact CD2-CG1 4.02Å; F148-V168 WeakPolarHBondContact CD2-O 3.42Å; F148-V168 HydrophobicContact CE2-CG1 4.32Å; F148-L256 HydrophobicContact CE2-CD1 4Å; F148-I463 HydrophobicContact CD1-CD1 4.31Å; F148-I463 HydrophobicContact CD2-CD1 4.03Å; F148-I463 HydrophobicContact CD2-CG1 4.45Å; F148-I463 HydrophobicContact CE1-CD1 4.31Å; F148-I463 HydrophobicContact CE2-CD1 4.06Å; F148-I463 HydrophobicContact CG-CD1 4.17Å; F148-I463 HydrophobicContact CZ-CD1 4.19Å
149A98.1Very high96.5Very high0 Ų029 Ų290%015%0.146CC..EExtended strand (participates in β ladder)trans-137143-173.700000113.2W27 L147 Y156 V168 L169 S170W27-A149 HydrophobicContact CB-CB 3.57Å; W27-A149 HydrophobicContact CG-CB 4.35Å; L147-A149 HydrophobicContact CD2-CB 3.76Å; A149-Y156 HydrophobicContact CB-CD1 4.33Å; A149-Y156 HydrophobicContact CB-CD2 4.1Å; A149-Y156 HydrophobicContact CB-CG 3.72Å; A149-V168 PolarHBondContact N-O 3.03Å; A149-L169 HydrophobicContact CB-CD2 4.03Å; A149-L169 CarbonylContact O-C 3.6Å; A149-L169 WeakPolarHBondContact O-CA 3.48Å; A149-S170 PolarHBondContact O-N 3.05Å
150D96.3Very high96.5Very high2 Ų229.2 Ų29.21%0.01115%0.147CC..  trans-88.2125.6151.8-175-66.9000108.6H33 M37 I152 S170 R258H33-D150 IonicContact CE1-OD1 2.75Å; H33-D150 IonicContact CE1-OD2 2.91Å; H33-D150 IonicContact CG-OD1 3.58Å; H33-D150 IonicContact CG-OD2 3.91Å; H33-D150 IonicContact ND1-OD1 2.79Å; H33-D150 PolarHBondContact ND1-OD1 3.17Å; H33-D150 IonicContact ND1-OD2 3.65Å; H33-D150 PolarHBondContact ND1-OD2 3.33Å; M37-D150 HydrophobicContact SD-CB 3.68Å; D150-I152 PolarHBondContact O-N 3.35Å; D150-I152 VanDerWaalsContact O-N 3.15Å; D150-I152 VanDerWaalsContact OD1-CB 3.26Å; D150-I152 WeakPolarHBondContact OD1-CB 3.33Å; D150-I152 WeakPolarHBondContact OD1-CG2 3.35Å; D150-I152 PolarHBondContact OD1-N 3.09Å; D150-S170 WeakPolarHBondContact CA-O 3.36Å; D150-R258 IonicContact OD2-CZ 3.09Å; D150-R258 IonicContact OD2-NH1 3.33Å; D150-R258 PolarHBondContact OD2-NH1 3.46Å; D150-R258 IonicContact OD2-NH2 2.64Å; D150-R258 PolarHBondContact OD2-NH2 3.29Å
151P94.1Very high96.4Very high2 Ų226.3 Ų26.31%0.01314%0.138CC..THydrogen-bonded Turntrans-83.817.1-169.536.1-38.4000114.3Y153 Y156 S170 L171 W179P151-Y153 PolarHBondContact O-N 3.47Å; P151-Y156 HydrophobicContact CB-CD1 4.29Å; P151-Y156 HydrophobicContact CB-CE1 3.36Å; P151-Y156 HydrophobicContact CB-CE2 4.22Å; P151-Y156 WeakPolarHBondContact CB-OH 3.18Å; P151-S170 WeakPolarHBondContact CD-O 3.24Å; P151-L171 HydrophobicContact CG-CB 4.2Å; P151-L171 HydrophobicContact CG-CD1 3.44Å; P151-L171 VanDerWaalsContact CG-CD1 3.44Å; P151-L171 HydrophobicContact CG-CG 4.36Å; P151-W179 HydrophobicContact CB-CE3 4.36Å; P151-W179 HydrophobicContact CB-CH2 4.39Å; P151-W179 HydrophobicContact CB-CZ3 3.66Å; P151-W179 HydrophobicContact CG-CE3 4.37Å; P151-W179 HydrophobicContact CG-CZ3 3.85Å; P151-W179 VanDerWaalsContact O-CH2 3.3Å; P151-W179 WeakPolarHBondContact O-CH2 3.42Å; P151-W179 WeakPolarHBondContact O-CZ3 3.45Å
152I91.8Very high96.4Very high82 Ų8223.1 Ų23.142%0.42112%0.124SC..THydrogen-bonded Turntrans-59.1-30.7176.6-168.263.9000113T29 D150T29-I152 WeakPolarHBondContact OG1-CG2 3.38Å; D150-I152 PolarHBondContact O-N 3.35Å; D150-I152 VanDerWaalsContact O-N 3.15Å; D150-I152 VanDerWaalsContact OD1-CB 3.26Å; D150-I152 WeakPolarHBondContact OD1-CB 3.33Å; D150-I152 WeakPolarHBondContact OD1-CG2 3.35Å; D150-I152 PolarHBondContact OD1-N 3.09Å
153Y92.9Very high96.5Very high26 Ų2623.9 Ų23.910%0.10212%0.124CC..SBendtrans-112.3142.2171.1-65-65.4000110.4Y28 E30 P151 Y156Y28-Y153 AromaticContact CD2-CD2 3.85Å; Y28-Y153 HydrophobicContact CD2-CD2 3.85Å; Y28-Y153 HydrophobicContact CD2-CE2 4.42Å; Y28-Y153 HydrophobicContact CD2-CG 4.4Å; Y28-Y153 HydrophobicContact CE2-CD1 4.43Å; Y28-Y153 AromaticContact CE2-CD2 3.56Å; Y28-Y153 HydrophobicContact CE2-CD2 3.56Å; Y28-Y153 HydrophobicContact CE2-CE2 4.29Å; Y28-Y153 AromaticContact CE2-CG 3.66Å; Y28-Y153 HydrophobicContact CE2-CG 3.66Å; E30-Y153 HydrophobicContact CB-CE2 4.27Å; E30-Y153 HydrophobicContact CG-CE2 3.88Å; P151-Y153 PolarHBondContact O-N 3.47Å; Y153-Y156 WeakPolarHBondContact O-CD1 3.4Å; Y153-Y156 WeakPolarHBondContact O-CE1 3.36Å
154P93.8Very high96.5Very high14 Ų1421.6 Ų21.69%0.09113%0.127CC..SBendtrans-71.4169.8179.432.5-35.8000112W27 I231W27-P154 WeakPolarHBondContact CZ2-O 3.44Å; W27-P154 PolarHBondContact NE1-O 2.92Å; P154-I231 HydrophobicContact CB-CD1 4.19Å
155G95.3Very high96.5Very high0 Ų021.5 Ų21.50%013%0.129CC..  trans102.9-17.3168.600000116.2W27 L126 D157 L158 T159 Y235W27-G155 VanDerWaalsContact CZ2-C 3.44Å; L126-G155 VanDerWaalsContact CD1-CA 3.48Å; G155-D157 VanDerWaalsContact C-N 3.28Å; G155-D157 PolarHBondContact O-N 2.98Å; G155-L158 PolarHBondContact O-N 3.05Å; G155-T159 VanDerWaalsContact O-CB 3.24Å; G155-T159 WeakPolarHBondContact O-CB 3.3Å; G155-T159 PolarHBondContact O-N 2.95Å; G155-T159 PolarHBondContact O-OG1 3.09Å; G155-Y235 WeakPolarHBondContact CA-OH 3.48Å; G155-Y235 PolarHBondContact N-OH 3.09Å
156Y96.9Very high96.5Very high1 Ų119 Ų190%0.00412%0.116CC..Hα-helixtrans-59.5-39.5177.155.9-92.6000112.3L147 A149 P151 Y153 A160 L167 L169 L249L147-Y156 WeakPolarHBondContact CD1-O 3.27Å; A149-Y156 HydrophobicContact CB-CD1 4.33Å; A149-Y156 HydrophobicContact CB-CD2 4.1Å; A149-Y156 HydrophobicContact CB-CG 3.72Å; P151-Y156 HydrophobicContact CB-CD1 4.29Å; P151-Y156 HydrophobicContact CB-CE1 3.36Å; P151-Y156 HydrophobicContact CB-CE2 4.22Å; P151-Y156 WeakPolarHBondContact CB-OH 3.18Å; Y153-Y156 WeakPolarHBondContact O-CD1 3.4Å; Y153-Y156 WeakPolarHBondContact O-CE1 3.36Å; Y156-A160 VanDerWaalsContact O-CB 3.31Å; Y156-A160 WeakPolarHBondContact O-CB 3.17Å; Y156-A160 PolarHBondContact O-N 3.12Å; Y156-L167 HydrophobicContact CD2-CD1 4.05Å; Y156-L167 HydrophobicContact CD2-CD2 3.92Å; Y156-L167 HydrophobicContact CE2-CD2 4.2Å; Y156-L169 HydrophobicContact CD2-CD2 3.56Å; Y156-L169 HydrophobicContact CE2-CD1 4.05Å; Y156-L169 HydrophobicContact CE2-CD2 3.41Å; Y156-L169 VanDerWaalsContact CE2-CD2 3.41Å; Y156-L169 HydrophobicContact CE2-CG 4.38Å; Y156-L169 HydrophobicContact CG-CD2 4.47Å; Y156-L249 HydrophobicContact CE2-CD2 3.78Å; Y156-L249 VanDerWaalsContact OH-CD2 3.29Å; Y156-L249 WeakPolarHBondContact OH-CD2 3.46Å
157D96.8Very high96.5Very high4 Ų419.4 Ų19.42%0.02112%0.118CC..Hα-helixtrans-75.8-44.1-177.757.1-24.8000111.7G155 T159 A160 D161 L167 Y235 N245 M248 L249G155-D157 VanDerWaalsContact C-N 3.28Å; G155-D157 PolarHBondContact O-N 2.98Å; D157-T159 VanDerWaalsContact C-N 3.32Å; D157-T159 PolarHBondContact O-N 3.06Å; D157-A160 PolarHBondContact O-N 2.7Å; D157-D161 WeakPolarHBondContact O-CB 3.43Å; D157-D161 PolarHBondContact O-N 3.42Å; D157-L167 HydrophobicContact CB-CD2 3.93Å; D157-Y235 WeakPolarHBondContact OD1-CE2 3.49Å; D157-Y235 PolarHBondContact OD1-OH 3.31Å; D157-Y235 WeakPolarHBondContact OD2-CE2 3.5Å; D157-N245 PolarHBondContact OD2-ND2 3.31Å; D157-M248 HydrophobicContact CB-CB 3.95Å; D157-M248 VanDerWaalsContact OD2-CB 3.27Å; D157-M248 WeakPolarHBondContact OD2-CB 3.11Å; D157-L249 HydrophobicContact CB-CD2 4.39Å
158L97Very high96.5Very high0 Ų019.4 Ų19.40%012%0.118CC..Hα-helixtrans-60.4-42.8171176.461000111.4V130 G155 D161 I162 Y234 Y235 V238 K239 M248V130-L158 HydrophobicContact CG1-CD2 4.47Å; G155-L158 PolarHBondContact O-N 3.05Å; L158-D161 PolarHBondContact O-N 2.71Å; L158-I162 HydrophobicContact CD1-CD1 4Å; L158-I162 HydrophobicContact CD1-CG1 4.3Å; L158-I162 HydrophobicContact CG-CD1 3.92Å; L158-I162 VanDerWaalsContact O-CG1 3.28Å; L158-I162 WeakPolarHBondContact O-CG1 3.48Å; L158-I162 PolarHBondContact O-N 3.14Å; L158-Y234 HydrophobicContact CD2-CE1 4.45Å; L158-Y235 HydrophobicContact CB-CD1 4.49Å; L158-Y235 HydrophobicContact CB-CD2 4.09Å; L158-Y235 HydrophobicContact CB-CE1 4.17Å; L158-Y235 HydrophobicContact CB-CE2 3.76Å; L158-Y235 HydrophobicContact CB-CG 4.44Å; L158-Y235 HydrophobicContact CD2-CD1 3.79Å; L158-Y235 HydrophobicContact CD2-CE1 3.99Å; L158-Y235 HydrophobicContact CD2-CG 4.07Å; L158-V238 HydrophobicContact CD2-CB 4.17Å; L158-V238 HydrophobicContact CD2-CG1 4.1Å; L158-V238 HydrophobicContact CD2-CG2 4.42Å; L158-K239 HydrophobicContact CD1-CD 3.89Å; L158-K239 HydrophobicContact CD1-CG 3.84Å; L158-M248 HydrophobicContact CD1-CE 4.08Å
159T97.4Very high96.5Very high0 Ų019.3 Ų19.30%012%0.118CC..Hα-helixtrans-67.5-44.5179.2-57.40000111.2W27 V130 L139 L147 G155 D157 D161 I162 L163W27-T159 VanDerWaalsContact CH2-OG1 3.25Å; W27-T159 WeakPolarHBondContact CH2-OG1 3.46Å; W27-T159 HydrophobicContact CZ3-CG2 3.93Å; W27-T159 VanDerWaalsContact CZ3-OG1 3.24Å; W27-T159 WeakPolarHBondContact CZ3-OG1 3.08Å; V130-T159 WeakPolarHBondContact CG1-OG1 3.26Å; L139-T159 HydrophobicContact CD1-CG2 4.3Å; L147-T159 HydrophobicContact CD1-CG2 4.23Å; G155-T159 VanDerWaalsContact O-CB 3.24Å; G155-T159 WeakPolarHBondContact O-CB 3.3Å; G155-T159 PolarHBondContact O-N 2.95Å; G155-T159 PolarHBondContact O-OG1 3.09Å; D157-T159 VanDerWaalsContact C-N 3.32Å; D157-T159 PolarHBondContact O-N 3.06Å; T159-D161 VanDerWaalsContact C-N 3.27Å; T159-D161 PolarHBondContact O-N 2.79Å; T159-I162 PolarHBondContact O-N 3.44Å; T159-L163 HydrophobicContact CG2-CD1 3.85Å; T159-L163 HydrophobicContact CG2-CG 4.22Å; T159-L163 WeakPolarHBondContact O-CB 3.3Å; T159-L163 VanDerWaalsContact O-CG 3.27Å; T159-L163 WeakPolarHBondContact O-CG 3.4Å; T159-L163 PolarHBondContact O-N 3.18Å
160A97.6Very high96.5Very high5 Ų519.4 Ų19.44%0.04112%0.119CC..Hα-helixtrans-57.1-42.8174.600000111.6L147 Y156 D157 L163 G164 I165 L167L147-A160 HydrophobicContact CB-CB 4.16Å; L147-A160 HydrophobicContact CD1-CB 4.05Å; Y156-A160 VanDerWaalsContact O-CB 3.31Å; Y156-A160 WeakPolarHBondContact O-CB 3.17Å; Y156-A160 PolarHBondContact O-N 3.12Å; D157-A160 PolarHBondContact O-N 2.7Å; A160-L163 PolarHBondContact O-N 3.42Å; A160-G164 PolarHBondContact O-N 2.72Å; A160-I165 HydrophobicContact CB-CG1 4.36Å; A160-I165 PolarHBondContact O-N 3.14Å; A160-L167 HydrophobicContact CB-CB 4.19Å; A160-L167 HydrophobicContact CB-CD1 4.38Å
161D96.7Very high96.5Very high62 Ų6219.5 Ų19.533%0.33212%0.119SC..Hα-helixtrans-64.3-44176.3-179.179.7000112.5D157 L158 T159 L163 G164 K239 M248D157-D161 WeakPolarHBondContact O-CB 3.43Å; D157-D161 PolarHBondContact O-N 3.42Å; L158-D161 PolarHBondContact O-N 2.71Å; T159-D161 VanDerWaalsContact C-N 3.27Å; T159-D161 PolarHBondContact O-N 2.79Å; D161-L163 VanDerWaalsContact C-N 3.32Å; D161-L163 PolarHBondContact O-N 2.93Å; D161-G164 PolarHBondContact O-N 2.88Å; D161-K239 WeakPolarHBondContact OD2-CE 2.95Å; D161-K239 IonicContact OD2-NZ 3.61Å; D161-K239 PolarHBondContact OD2-NZ 3.03Å; D161-M248 HydrophobicContact CB-CE 4.31Å; D161-M248 HydrophobicContact CB-SD 4.41Å
162I96.3Very high96.5Very high51 Ų5120.4 Ų20.426%0.26212%0.122SC..Hα-helixtrans-63.6-38.1176.4-68164.1000111.7M136 L158 T159 G164 V238M136-I162 HydrophobicContact CE-CB 4.26Å; M136-I162 HydrophobicContact CE-CG2 3.52Å; L158-I162 HydrophobicContact CD1-CD1 4Å; L158-I162 HydrophobicContact CD1-CG1 4.3Å; L158-I162 HydrophobicContact CG-CD1 3.92Å; L158-I162 VanDerWaalsContact O-CG1 3.28Å; L158-I162 WeakPolarHBondContact O-CG1 3.48Å; L158-I162 PolarHBondContact O-N 3.14Å; T159-I162 PolarHBondContact O-N 3.44Å; I162-G164 VanDerWaalsContact C-N 3.33Å; I162-V238 HydrophobicContact CD1-CG1 4.08Å
163L97.2Very high96.7Very high34 Ų3418.7 Ų18.718%0.17811%0.112CC..Hα-helixtrans-79.7-16.3178.4-63.4179000112.7L25 M136 L139 K140 T159 A160 D161 I165L25-L163 HydrophobicContact CD2-CD1 3.72Å; M136-L163 HydrophobicContact CE-CD2 4.23Å; L139-L163 HydrophobicContact CB-CD1 4.29Å; L139-L163 HydrophobicContact CB-CD2 4.06Å; K140-L163 HydrophobicContact CB-CD2 4.4Å; K140-L163 HydrophobicContact CG-CD2 3.68Å; T159-L163 HydrophobicContact CG2-CD1 3.85Å; T159-L163 HydrophobicContact CG2-CG 4.22Å; T159-L163 WeakPolarHBondContact O-CB 3.3Å; T159-L163 VanDerWaalsContact O-CG 3.27Å; T159-L163 WeakPolarHBondContact O-CG 3.4Å; T159-L163 PolarHBondContact O-N 3.18Å; A160-L163 PolarHBondContact O-N 3.42Å; D161-L163 VanDerWaalsContact C-N 3.32Å; D161-L163 PolarHBondContact O-N 2.93Å; L163-I165 HydrophobicContact CB-CD1 4.07Å; L163-I165 HydrophobicContact CB-CG1 4.01Å; L163-I165 HydrophobicContact CB-CG2 4.21Å; L163-I165 HydrophobicContact CD1-CD1 3.89Å
164G96.8Very high96.8Very high67 Ų6717.9 Ų17.969%0.69111%0.11SC*.THydrogen-bonded Turntrans69.531.8-177.700000113.5A160 D161 I162A160-G164 PolarHBondContact O-N 2.72Å; D161-G164 PolarHBondContact O-N 2.88Å; I162-G164 VanDerWaalsContact C-N 3.33Å
165I97.9Very high96.9Very high27 Ų2719.8 Ų19.814%0.13812%0.119CC..  trans-113.7150-174.965-178.2000112.2Y144 L147 A160 L163Y144-I165 VanDerWaalsContact O-CG2 3.23Å; Y144-I165 WeakPolarHBondContact O-CG2 3.37Å; L147-I165 HydrophobicContact CB-CD1 3.89Å; L147-I165 HydrophobicContact CB-CG1 4.24Å; A160-I165 HydrophobicContact CB-CG1 4.36Å; A160-I165 PolarHBondContact O-N 3.14Å; L163-I165 HydrophobicContact CB-CD1 4.07Å; L163-I165 HydrophobicContact CB-CG1 4.01Å; L163-I165 HydrophobicContact CB-CG2 4.21Å; L163-I165 HydrophobicContact CD1-CD1 3.89Å
166P98.3Very high96.9Very high21 Ų2119.8 Ų19.814%0.13612%0.119CC..  trans-56.1152.8173.1-26.735.2000113.8D145 V146 L147 D253 T466D145-P166 WeakPolarHBondContact O-CD 3.42Å; V146-P166 HydrophobicContact CG2-CB 4.32Å; L147-P166 PolarHBondContact N-O 2.76Å; P166-D253 WeakPolarHBondContact CA-OD2 3.36Å; P166-D253 VanDerWaalsContact CB-OD2 3.29Å; P166-D253 WeakPolarHBondContact CB-OD2 3.16Å; P166-T466 HydrophobicContact CB-CG2 3.37Å; P166-T466 HydrophobicContact CG-CG2 4.29Å
167L98.6Very high96.9Very high8 Ų820.3 Ų20.34%0.04212%0.122CC..EExtended strand (participates in β ladder)trans-124.9124.4-176.8177.561.6000111.9L147 Y156 D157 A160 L169 V252 D253 I254L147-L167 HydrophobicContact CB-CD1 4.13Å; L147-L167 HydrophobicContact CD2-CD1 3.57Å; L147-L167 HydrophobicContact CG-CD1 4.43Å; Y156-L167 HydrophobicContact CD2-CD1 4.05Å; Y156-L167 HydrophobicContact CD2-CD2 3.92Å; Y156-L167 HydrophobicContact CE2-CD2 4.2Å; D157-L167 HydrophobicContact CB-CD2 3.93Å; A160-L167 HydrophobicContact CB-CB 4.19Å; A160-L167 HydrophobicContact CB-CD1 4.38Å; L167-L169 HydrophobicContact CD1-CD2 3.8Å; L167-L169 HydrophobicContact CD2-CD2 4.14Å; L167-L169 HydrophobicContact CG-CD2 3.94Å; L167-L169 HydrophobicContact CG-CG 4.41Å; L167-V252 HydrophobicContact CD2-CG2 3.63Å; L167-V252 HydrophobicContact CG-CG2 4.2Å; L167-D253 PolarHBondContact N-OD2 3.08Å; L167-D253 WeakPolarHBondContact O-CB 3.39Å; L167-D253 PolarHBondContact O-N 3.02Å; L167-I254 PolarHBondContact O-N 3.27Å
168V98.7Very high96.8Very high0 Ų020.2 Ų20.20%012%0.121CC..EExtended strand (participates in β ladder)trans-115.3126.2171.2-179.40000109.4V146 L147 F148 A149 I254 L256 I463 T466V146-V168 HydrophobicContact CG2-CG2 3.86Å; L147-V168 PolarHBondContact O-N 3.19Å; F148-V168 WeakPolarHBondContact CA-O 3.5Å; F148-V168 HydrophobicContact CD2-CB 4.19Å; F148-V168 HydrophobicContact CD2-CG1 4.02Å; F148-V168 WeakPolarHBondContact CD2-O 3.42Å; F148-V168 HydrophobicContact CE2-CG1 4.32Å; A149-V168 PolarHBondContact N-O 3.03Å; V168-I254 WeakPolarHBondContact CA-O 3.17Å; V168-I254 HydrophobicContact CG1-CB 4.15Å; V168-I254 HydrophobicContact CG1-CG2 4.29Å; V168-I254 HydrophobicContact CG2-CB 4.22Å; V168-L256 HydrophobicContact CG1-CD1 3.78Å; V168-L256 HydrophobicContact CG1-CG 3.83Å; V168-I463 HydrophobicContact CB-CG1 4.45Å; V168-I463 HydrophobicContact CG1-CG1 3.97Å; V168-T466 HydrophobicContact CG2-CG2 3.88Å
169L98.3Very high96.8Very high0 Ų022.4 Ų22.40%013%0.13CC..EExtended strand (participates in β ladder)trans-100.4138.5176.7-60.3-173.3000111A149 Y156 L167 L249 V252 I254 W255 L256A149-L169 HydrophobicContact CB-CD2 4.03Å; A149-L169 CarbonylContact O-C 3.6Å; A149-L169 WeakPolarHBondContact O-CA 3.48Å; Y156-L169 HydrophobicContact CD2-CD2 3.56Å; Y156-L169 HydrophobicContact CE2-CD1 4.05Å; Y156-L169 HydrophobicContact CE2-CD2 3.41Å; Y156-L169 VanDerWaalsContact CE2-CD2 3.41Å; Y156-L169 HydrophobicContact CE2-CG 4.38Å; Y156-L169 HydrophobicContact CG-CD2 4.47Å; L167-L169 HydrophobicContact CD1-CD2 3.8Å; L167-L169 HydrophobicContact CD2-CD2 4.14Å; L167-L169 HydrophobicContact CG-CD2 3.94Å; L167-L169 HydrophobicContact CG-CG 4.41Å; L169-L249 HydrophobicContact CD1-CD2 4.16Å; L169-V252 HydrophobicContact CB-CG1 4.39Å; L169-V252 HydrophobicContact CD1-CB 4.41Å; L169-V252 HydrophobicContact CD1-CG1 3.97Å; L169-V252 HydrophobicContact CD1-CG2 3.55Å; L169-V252 HydrophobicContact CG-CG1 3.77Å; L169-V252 HydrophobicContact CG-CG2 3.93Å; L169-I254 PolarHBondContact N-O 3.46Å; L169-W255 HydrophobicContact CB-CE3 4.48Å; L169-W255 HydrophobicContact CD1-CD2 4.37Å; L169-W255 HydrophobicContact CD1-CE3 3.86Å; L169-W255 HydrophobicContact CD1-CH2 3.82Å; L169-W255 HydrophobicContact CD1-CZ2 4.34Å; L169-W255 HydrophobicContact CD1-CZ3 3.56Å; L169-L256 WeakPolarHBondContact O-CA 3.28Å; L169-L256 WeakPolarHBondContact O-CB 3.48Å; L169-L256 PolarHBondContact O-N 2.78Å
170S97.7Very high96.7Very high1 Ų122.4 Ų22.41%0.00713%0.13CC..EExtended strand (participates in β ladder)trans-99.4110.6156.7-171.50000107.6A149 D150 P151 L256 R258A149-S170 PolarHBondContact O-N 3.05Å; D150-S170 WeakPolarHBondContact CA-O 3.36Å; P151-S170 WeakPolarHBondContact CD-O 3.24Å; S170-L256 CarbonylContact C-O 3.6Å; S170-L256 WeakPolarHBondContact CA-O 3.16Å; S170-R258 PolarHBondContact O-NH1 2.91Å; S170-R258 WeakPolarHBondContact OG-CD 3.4Å; S170-R258 WeakPolarHBondContact OG-CG 3.42Å; S170-R258 PolarHBondContact OG-NH1 2.8Å
171L96.7Very high96.6Very high5 Ų524.4 Ų24.43%0.02614%0.136CC..EExtended strand (participates in β ladder)trans-126.1136.4-177177.167.8000110.6P151 F173 W179 E180 W255 L256 M257 R258P151-L171 HydrophobicContact CG-CB 4.2Å; P151-L171 HydrophobicContact CG-CD1 3.44Å; P151-L171 VanDerWaalsContact CG-CD1 3.44Å; P151-L171 HydrophobicContact CG-CG 4.36Å; L171-F173 WeakPolarHBondContact CD1-O 3.46Å; L171-W179 HydrophobicContact CD1-CE3 4.34Å; L171-W179 HydrophobicContact CD1-CZ3 4.48Å; L171-E180 HydrophobicContact CD2-CG 3.79Å; L171-W255 HydrophobicContact CD2-CE3 3.91Å; L171-W255 HydrophobicContact CD2-CZ3 3.82Å; L171-L256 PolarHBondContact N-O 3.41Å; L171-M257 HydrophobicContact CB-CE 4.48Å; L171-M257 HydrophobicContact CB-SD 4.24Å; L171-M257 HydrophobicContact CD2-CE 4.15Å; L171-M257 HydrophobicContact CD2-SD 4.23Å; L171-M257 HydrophobicContact CG-CE 4.21Å; L171-M257 HydrophobicContact CG-SD 4.46Å; L171-M257 CarbonylContact O-C 3.54Å; L171-M257 VanDerWaalsContact O-CA 3.24Å; L171-M257 WeakPolarHBondContact O-CA 3.33Å; L171-R258 PolarHBondContact O-N 3.37Å
172R94.6Very high96.4Very high21 Ų2125.2 Ų25.28%0.07914%0.139CC..SBendtrans-87.4-51170.7174.145.3-166.797.93.9111.9R258 T259 F263 T376 N401R172-R258 HydrophobicContact CB-CB 4.29Å; R172-T259 VanDerWaalsContact CD-CG2 3.49Å; R172-F263 VanDerWaalsContact NH2-CE1 3.32Å; R172-T376 PolarHBondContact NE-OG1 3.34Å; R172-N401 PolarHBondContact NH2-OD1 3.42Å
173F95.3Very high96.3Very high45 Ų4522.8 Ų22.820%0.19713%0.126CC..  trans-168161.4167.262.7-90.4000108.1L171 E180 A196 M197 D397L171-F173 WeakPolarHBondContact CD1-O 3.46Å; F173-E180 VanDerWaalsContact CA-OE1 3.3Å; F173-E180 WeakPolarHBondContact CA-OE1 3.34Å; F173-A196 HydrophobicContact CB-CB 4.06Å; F173-A196 HydrophobicContact CD2-CB 3.72Å; F173-A196 HydrophobicContact CG-CB 4Å; F173-M197 HydrophobicContact CE2-CG 3.82Å; F173-M197 HydrophobicContact CE2-SD 3.86Å; F173-M197 HydrophobicContact CZ-CG 4.28Å; F173-M197 HydrophobicContact CZ-SD 3.71Å; F173-D397 HydrophobicContact CE1-CB 3.43Å; F173-D397 VanDerWaalsContact CE1-CB 3.43Å; F173-D397 HydrophobicContact CZ-CB 3.57Å
174S95.4Very high96.2Very high10 Ų1021.2 Ų21.27%0.0712%0.118CC..  trans-105.3157.4153.873.50000110.2A176 H177 H178 W179 E180S174-A176 PolarHBondContact O-N 3.06Å; S174-H177 VanDerWaalsContact O-CA 3.3Å; S174-H177 WeakPolarHBondContact O-CA 3.42Å; S174-H177 PolarHBondContact O-N 3.07Å; S174-H177 VanDerWaalsContact OG-C 3.32Å; S174-H178 PolarHBondContact OG-N 3.21Å; S174-W179 PolarHBondContact OG-N 3.06Å; S174-E180 WeakPolarHBondContact CB-OE2 3.48Å; S174-E180 PolarHBondContact N-OE1 3.21Å; S174-E180 VanDerWaalsContact N-OE1 3.15Å; S174-E180 PolarHBondContact N-OE2 3.23Å; S174-E180 PolarHBondContact OG-OE2 2.99Å
175L94.6Very high96.1Very high54 Ų5419.5 Ų19.528%0.2839%0.092SC..G310 helixtrans-54.2129.4-177-179.261.5000110.5H177 H178 M197 F215 Q219 I223L175-H177 PolarHBondContact O-N 3.22Å; L175-H177 VanDerWaalsContact O-N 3.09Å; L175-H178 VanDerWaalsContact O-CB 3.27Å; L175-H178 WeakPolarHBondContact O-CB 3.4Å; L175-H178 PolarHBondContact O-N 2.67Å; L175-M197 HydrophobicContact CD1-CB 3.75Å; L175-M197 HydrophobicContact CD1-CG 3.66Å; L175-F215 HydrophobicContact CD1-CZ 4.49Å; L175-Q219 HydrophobicContact CD2-CG 4.35Å; L175-Q219 HydrophobicContact CG-CB 4.45Å; L175-Q219 HydrophobicContact CG-CG 4.1Å; L175-I223 HydrophobicContact CB-CD1 3.96Å; L175-I223 HydrophobicContact CD2-CD1 4.3Å; L175-I223 HydrophobicContact CG-CD1 4.26Å
176A96.2Very high96Very high0 Ų018.4 Ų18.40%09%0.087CC..G310 helixtrans49.331-171.100000114.7S174 H178 R181 A195 A196 F215 Y216 Q219S174-A176 PolarHBondContact O-N 3.06Å; A176-H178 PolarHBondContact O-N 2.73Å; A176-H178 VanDerWaalsContact O-N 3.07Å; A176-R181 PolarHBondContact O-NE 3.31Å; A176-A195 HydrophobicContact CB-CB 4.02Å; A176-A196 PolarHBondContact N-O 3.23Å; A176-F215 HydrophobicContact CB-CD1 4.35Å; A176-F215 HydrophobicContact CB-CE1 4.3Å; A176-Y216 HydrophobicContact CB-CD1 3.87Å; A176-Y216 HydrophobicContact CB-CE1 4.26Å; A176-Y216 WeakPolarHBondContact O-CD1 3.07Å; A176-Y216 WeakPolarHBondContact O-CE1 3.46Å; A176-Q219 HydrophobicContact CB-CB 3.64Å; A176-Q219 HydrophobicContact CB-CG 3.9Å
177H96.3Very high95.8Very high11 Ų1119.1 Ų19.15%0.0519%0.092CC..G310 helixtrans5129.7-174.3-58.2-56.7000113.6S174 L175 W179 E180 R181 R267S174-H177 VanDerWaalsContact O-CA 3.3Å; S174-H177 WeakPolarHBondContact O-CA 3.42Å; S174-H177 PolarHBondContact O-N 3.07Å; S174-H177 VanDerWaalsContact OG-C 3.32Å; L175-H177 PolarHBondContact O-N 3.22Å; L175-H177 VanDerWaalsContact O-N 3.09Å; H177-W179 PolarHBondContact O-N 2.95Å; H177-E180 WeakPolarHBondContact CA-OE2 3.49Å; H177-E180 HydrophobicContact CB-CB 4.38Å; H177-E180 IonicContact CG-OE1 3.92Å; H177-E180 IonicContact ND1-OE1 3.33Å; H177-E180 PolarHBondContact ND1-OE1 3.1Å; H177-E180 VanDerWaalsContact ND1-OE1 3.1Å; H177-E180 PolarHBondContact O-N 2.81Å; H177-R181 HydrophobicContact CB-CG 3.97Å; H177-R181 WeakPolarHBondContact O-CB 3.34Å; H177-R181 WeakPolarHBondContact O-CG 3.47Å; H177-R181 PolarHBondContact O-N 3.08Å; H177-R267 PolarHBondContact CE1-NH1 2.99Å; H177-R267 PolarHBondContact ND1-NH1 2.94Å; H177-R267 PolarHBondContact NE2-NH1 2.85Å; H177-R267 VanDerWaalsContact NE2-NH1 3.15Å
178H95.9Very high95.7Very high3 Ų319.4 Ų19.41%0.01410%0.095CC..Hα-helixtrans-54.2-52.8-172.9-179.3-84.5000112.8S174 L175 A176 M182 D220 I223S174-H178 PolarHBondContact OG-N 3.21Å; L175-H178 VanDerWaalsContact O-CB 3.27Å; L175-H178 WeakPolarHBondContact O-CB 3.4Å; L175-H178 PolarHBondContact O-N 2.67Å; A176-H178 PolarHBondContact O-N 2.73Å; A176-H178 VanDerWaalsContact O-N 3.07Å; H178-M182 WeakPolarHBondContact O-CA 2.93Å; H178-M182 WeakPolarHBondContact O-CB 3.36Å; H178-M182 WeakPolarHBondContact O-CG 3.39Å; H178-M182 PolarHBondContact O-N 3.24Å; H178-D220 IonicContact CD2-OD1 2.69Å; H178-D220 PolarHBondContact CD2-OD1 3.38Å; H178-I223 HydrophobicContact CB-CD1 3.53Å
179W95.7Very high95.6Very high46 Ų4621.3 Ų21.317%0.17411%0.107CC..Iπ-helixtrans-64.1-45.2178.2-63.9-19.1000112.2P151 L171 S174 H177 R181 C183 G184 L249P151-W179 HydrophobicContact CB-CE3 4.36Å; P151-W179 HydrophobicContact CB-CH2 4.39Å; P151-W179 HydrophobicContact CB-CZ3 3.66Å; P151-W179 HydrophobicContact CG-CE3 4.37Å; P151-W179 HydrophobicContact CG-CZ3 3.85Å; P151-W179 VanDerWaalsContact O-CH2 3.3Å; P151-W179 WeakPolarHBondContact O-CH2 3.42Å; P151-W179 WeakPolarHBondContact O-CZ3 3.45Å; L171-W179 HydrophobicContact CD1-CE3 4.34Å; L171-W179 HydrophobicContact CD1-CZ3 4.48Å; S174-W179 PolarHBondContact OG-N 3.06Å; H177-W179 PolarHBondContact O-N 2.95Å; W179-R181 PolarHBondContact O-N 3.09Å; W179-C183 CarbonylContact O-C 3.55Å; W179-C183 WeakPolarHBondContact O-CA 2.95Å; W179-C183 WeakPolarHBondContact O-CB 2.9Å; W179-C183 PolarHBondContact O-N 3.41Å; W179-C183 VanDerWaalsContact O-N 3.08Å; W179-G184 PolarHBondContact O-N 2.89Å; W179-L249 HydrophobicContact CB-CD1 4.24Å; W179-L249 HydrophobicContact CD2-CD1 4.25Å; W179-L249 HydrophobicContact CG-CD1 3.94Å
180E96.2Very high95.5Very high0 Ų023.6 Ų23.60%012%0.122CC..Iπ-helixtrans-61-47179.8-57.695.2120.900111.2L171 F173 S174 H177 G184 Q185 L186 M257 F273L171-E180 HydrophobicContact CD2-CG 3.79Å; F173-E180 VanDerWaalsContact CA-OE1 3.3Å; F173-E180 WeakPolarHBondContact CA-OE1 3.34Å; S174-E180 WeakPolarHBondContact CB-OE2 3.48Å; S174-E180 PolarHBondContact N-OE1 3.21Å; S174-E180 VanDerWaalsContact N-OE1 3.15Å; S174-E180 PolarHBondContact N-OE2 3.23Å; S174-E180 PolarHBondContact OG-OE2 2.99Å; H177-E180 WeakPolarHBondContact CA-OE2 3.49Å; H177-E180 HydrophobicContact CB-CB 4.38Å; H177-E180 IonicContact CG-OE1 3.92Å; H177-E180 IonicContact ND1-OE1 3.33Å; H177-E180 PolarHBondContact ND1-OE1 3.1Å; H177-E180 VanDerWaalsContact ND1-OE1 3.1Å; H177-E180 PolarHBondContact O-N 2.81Å; E180-G184 CarbonylContact O-C 3.59Å; E180-G184 VanDerWaalsContact O-CA 3.24Å; E180-G184 WeakPolarHBondContact O-CA 3.36Å; E180-G184 PolarHBondContact O-N 2.99Å; E180-Q185 PolarHBondContact O-N 2.05Å; E180-L186 HydrophobicContact CB-CB 4.11Å; E180-L186 HydrophobicContact CB-CD2 4Å; E180-L186 WeakPolarHBondContact O-CB 3.29Å; E180-L186 PolarHBondContact O-N 3.5Å; E180-M257 HydrophobicContact CG-CE 4.11Å; E180-M257 HydrophobicContact CG-SD 4.4Å; E180-F273 HydrophobicContact CB-CE1 4.11Å; E180-F273 HydrophobicContact CB-CZ 4.48Å; E180-F273 HydrophobicContact CG-CE1 4.09Å
181R95.1Very high95.5Very high46 Ų4626.6 Ų26.617%0.17414%0.143CC..Iπ-helixtrans-77.3-54.4-178.3-65-179.9-35104.50.9112.7A176 H177 W179 Q185 L186 A188 D220A176-R181 PolarHBondContact O-NE 3.31Å; H177-R181 HydrophobicContact CB-CG 3.97Å; H177-R181 WeakPolarHBondContact O-CB 3.34Å; H177-R181 WeakPolarHBondContact O-CG 3.47Å; H177-R181 PolarHBondContact O-N 3.08Å; W179-R181 PolarHBondContact O-N 3.09Å; R181-Q185 VanDerWaalsContact O-CA 3.26Å; R181-Q185 WeakPolarHBondContact O-CA 3.49Å; R181-Q185 PolarHBondContact O-N 2.92Å; R181-L186 WeakPolarHBondContact CA-O 3.5Å; R181-A188 HydrophobicContact CG-CB 3.67Å; R181-D220 IonicContact CZ-OD2 2.74Å; R181-D220 IonicContact NH2-OD1 3.74Å; R181-D220 PolarHBondContact NH2-OD1 3.1Å; R181-D220 IonicContact NH2-OD2 3.11Å; R181-D220 PolarHBondContact NH2-OD2 3.15Å
182M93Very high95.5Very high79 Ų7930 Ų3039%0.38916%0.158SC..Iπ-helixtrans-80.1-41.7-168.1-57.7-61.3-72.400111.5H178 Q185H178-M182 WeakPolarHBondContact O-CA 2.93Å; H178-M182 WeakPolarHBondContact O-CB 3.36Å; H178-M182 WeakPolarHBondContact O-CG 3.39Å; H178-M182 PolarHBondContact O-N 3.24Å; M182-Q185 PolarHBondContact O-NE2 3.26Å; M182-Q185 VanDerWaalsContact O-NE2 3.1Å
183C94Very high95.6Very high0 Ų029.3 Ų29.30%016%0.156CC..Iπ-helixtrans-94.8-44.7-178.8-39.20000111.7W179 C246 L249 R250 H480W179-C183 CarbonylContact O-C 3.55Å; W179-C183 WeakPolarHBondContact O-CA 2.95Å; W179-C183 WeakPolarHBondContact O-CB 2.9Å; W179-C183 PolarHBondContact O-N 3.41Å; W179-C183 VanDerWaalsContact O-N 3.08Å; C183-C246 HydrophobicContact CB-CB 3.95Å; C183-C246 WeakPolarHBondContact CB-SG 3.47Å; C183-C246 WeakPolarHBondContact SG-CA 3.36Å; C183-C246 WeakPolarHBondContact SG-CB 3.21Å; C183-C246 CovalentContact SG-SG 2.05Å; C183-C246 PolarHBondContact SG-SG 2.82Å; C183-L249 HydrophobicContact CB-CB 3.62Å; C183-L249 HydrophobicContact CB-CD1 4.11Å; C183-R250 WeakPolarHBondContact O-CG 3.25Å; C183-H480 PolarHBondContact O-CE1 3.48Å
184G95Very high95.7Very high1 Ų127.6 Ų27.61%0.0115%0.149CC..THydrogen-bonded Turntrans-87.4-6.1-177.300000115.6W179 E180 L186W179-G184 PolarHBondContact O-N 2.89Å; E180-G184 CarbonylContact O-C 3.59Å; E180-G184 VanDerWaalsContact O-CA 3.24Å; E180-G184 WeakPolarHBondContact O-CA 3.36Å; E180-G184 PolarHBondContact O-N 2.99Å; G184-L186 PolarHBondContact O-N 3.15Å; G184-L186 VanDerWaalsContact O-N 3.14Å
185Q94.8Very high95.8Very high31 Ų3127.1 Ų27.115%0.14515%0.146CC..  trans60.116.2178.9-59.2-65.1-44.900115.3E180 R181 M182 P187 L270 V477 A479 H480E180-Q185 PolarHBondContact O-N 2.05Å; R181-Q185 VanDerWaalsContact O-CA 3.26Å; R181-Q185 WeakPolarHBondContact O-CA 3.49Å; R181-Q185 PolarHBondContact O-N 2.92Å; M182-Q185 PolarHBondContact O-NE2 3.26Å; M182-Q185 VanDerWaalsContact O-NE2 3.1Å; Q185-P187 WeakPolarHBondContact O-CD 3.2Å; Q185-L270 HydrophobicContact CB-CD1 4.48Å; Q185-L270 WeakPolarHBondContact O-CD1 3.48Å; Q185-V477 HydrophobicContact CB-CG2 3.97Å; Q185-A479 HydrophobicContact CB-CB 4.06Å; Q185-A479 HydrophobicContact CG-CB 4.13Å; Q185-H480 WeakPolarHBondContact CG-CE1 3.47Å; Q185-H480 WeakPolarHBondContact CG-ND1 3.3Å
186L95.4Very high95.9Very high4 Ų424.9 Ų24.92%0.02114%0.135CC..  trans-64.7121.4174.6-175.269.6000109.5E180 R181 G184 A188 L270 F273E180-L186 HydrophobicContact CB-CB 4.11Å; E180-L186 HydrophobicContact CB-CD2 4Å; E180-L186 WeakPolarHBondContact O-CB 3.29Å; E180-L186 PolarHBondContact O-N 3.5Å; R181-L186 WeakPolarHBondContact CA-O 3.5Å; G184-L186 PolarHBondContact O-N 3.15Å; G184-L186 VanDerWaalsContact O-N 3.14Å; L186-A188 PolarHBondContact O-N 3.29Å; L186-L270 HydrophobicContact CD1-CB 4.32Å; L186-L270 HydrophobicContact CD1-CG 4Å; L186-F273 HydrophobicContact CB-CE1 4.04Å; L186-F273 HydrophobicContact CB-CE2 4.17Å; L186-F273 HydrophobicContact CB-CZ 3.84Å; L186-F273 HydrophobicContact CD1-CB 4.42Å; L186-F273 HydrophobicContact CD1-CD1 4.19Å; L186-F273 HydrophobicContact CD1-CD2 4.24Å; L186-F273 HydrophobicContact CD1-CG 4.03Å; L186-F273 HydrophobicContact CD2-CD1 3.85Å; L186-F273 HydrophobicContact CD2-CE1 3.86Å; L186-F273 HydrophobicContact CG-CD1 4.42Å; L186-F273 HydrophobicContact CG-CE1 4.37Å
187P95.1Very high95.9Very high37 Ų3727.5 Ų27.524%0.2415%0.148CC..  trans-67.3130-179.6-17.529.7000111.4Q185 P268 L270Q185-P187 WeakPolarHBondContact O-CD 3.2Å; P187-P268 HydrophobicContact CB-CB 3.94Å; P187-P268 HydrophobicContact CB-CG 4.32Å; P187-P268 HydrophobicContact CG-CB 4.21Å; P187-L270 HydrophobicContact CG-CD2 4.5Å
188A96.3Very high95.9Very high13 Ų1327.3 Ų27.311%0.10715%0.148CC..  trans-132.885.3168.800000110R181 L186 P190 V193R181-A188 HydrophobicContact CG-CB 3.67Å; L186-A188 PolarHBondContact O-N 3.29Å; A188-P190 WeakPolarHBondContact O-CD 3.43Å; A188-V193 HydrophobicContact CB-CB 4.14Å; A188-V193 HydrophobicContact CB-CG1 3.85Å
189P96.4Very high95.9Very high40 Ų4032.8 Ų32.826%0.2617%0.172SC..  trans-61.3119.8177.9-23.634.7000110.6S191 F192 V193 P268P189-S191 PolarHBondContact O-N 3.31Å; P189-F192 HydrophobicContact CB-CD1 4.08Å; P189-F192 HydrophobicContact CB-CE1 3.6Å; P189-F192 HydrophobicContact CB-CZ 4.25Å; P189-F192 HydrophobicContact CG-CE1 3.71Å; P189-F192 HydrophobicContact CG-CZ 3.93Å; P189-F192 PolarHBondContact O-N 2.78Å; P189-V193 WeakPolarHBondContact O-CB 3.44Å; P189-V193 PolarHBondContact O-N 3.18Å; P189-P268 HydrophobicContact CG-CG 4.31Å
190P96.7Very high96Very high49 Ų4931.4 Ų31.432%0.31817%0.168SC..THydrogen-bonded Turntrans-69.3-7.4-174.629-36.7000113.2A188 F192 N212 V213 Y216A188-P190 WeakPolarHBondContact O-CD 3.43Å; P190-F192 VanDerWaalsContact C-N 3.31Å; P190-N212 PolarHBondContact O-ND2 3.48Å; P190-V213 HydrophobicContact CB-CG2 3.82Å; P190-V213 HydrophobicContact CG-CG2 3.99Å; P190-Y216 HydrophobicContact CB-CD2 3.77Å; P190-Y216 HydrophobicContact CB-CE2 3.8Å
191S96.2Very high96Very high63 Ų6333.1 Ų33.144%0.44118%0.178SC..THydrogen-bonded Turntrans-70.1-24.3175.5530000113.8P189 R209P189-S191 PolarHBondContact O-N 3.31Å; S191-R209 VanDerWaalsContact O-CD 3.3Å; S191-R209 WeakPolarHBondContact O-CD 3.28Å
192F96.6Very high96.1Very high78 Ų7833.2 Ų33.234%0.34218%0.182SC..THydrogen-bonded Turntrans-148.5-12179.871.7-92000114.6P189 P190 P194 D202 P268P189-F192 HydrophobicContact CB-CD1 4.08Å; P189-F192 HydrophobicContact CB-CE1 3.6Å; P189-F192 HydrophobicContact CB-CZ 4.25Å; P189-F192 HydrophobicContact CG-CE1 3.71Å; P189-F192 HydrophobicContact CG-CZ 3.93Å; P189-F192 PolarHBondContact O-N 2.78Å; P190-F192 VanDerWaalsContact C-N 3.31Å; F192-P194 VanDerWaalsContact O-CD 3.28Å; F192-P194 WeakPolarHBondContact O-CD 3.41Å; F192-D202 VanDerWaalsContact O-CA 3.29Å; F192-D202 WeakPolarHBondContact O-CA 3.45Å; F192-P268 HydrophobicContact CZ-CG 4.23Å
193V97.8Very high96.3Very high5 Ų537.5 Ų37.53%0.0320%0.199CC..SBendtrans-93.4106172.4-174.30000108.5A188 P189 N212 Y216 R267A188-V193 HydrophobicContact CB-CB 4.14Å; A188-V193 HydrophobicContact CB-CG1 3.85Å; P189-V193 WeakPolarHBondContact O-CB 3.44Å; P189-V193 PolarHBondContact O-N 3.18Å; V193-N212 PolarHBondContact O-ND2 3.49Å; V193-Y216 PolarHBondContact O-OH 2.89Å; V193-R267 HydrophobicContact CG1-CB 4.43Å; V193-R267 HydrophobicContact CG2-CB 3.83Å
194P97.5Very high96.5Very high10 Ų1038.7 Ų38.77%0.06520%0.204CC..PPolyproline II helixtrans-63.3138.9177.728.2-34.7000109.7F192 A196 L200 Y216 F265F192-P194 VanDerWaalsContact O-CD 3.28Å; F192-P194 WeakPolarHBondContact O-CD 3.41Å; P194-A196 PolarHBondContact O-N 3.06Å; P194-L200 HydrophobicContact CB-CB 3.73Å; P194-Y216 PolarHBondContact O-OH 3.45Å; P194-F265 HydrophobicContact CG-CD2 4.06Å
195A97.6Very high96.6Very high0 Ų042.7 Ų42.70%023%0.225CC..PPolyproline II helixtrans-62.9132.8172.800000109.2A176 M197 S198 N212 F215 Y216A176-A195 HydrophobicContact CB-CB 4.02Å; A195-M197 PolarHBondContact O-N 3.47Å; A195-S198 WeakPolarHBondContact O-CB 3.5Å; A195-S198 PolarHBondContact O-N 3.36Å; A195-S198 PolarHBondContact O-OG 2.98Å; A195-N212 WeakPolarHBondContact CB-OD1 3.36Å; A195-N212 PolarHBondContact N-OD1 3.32Å; A195-F215 HydrophobicContact CB-CD1 3.55Å; A195-F215 HydrophobicContact CB-CE1 4.07Å; A195-Y216 WeakPolarHBondContact CA-OH 3.2Å; A195-Y216 HydrophobicContact CB-CD1 4.05Å; A195-Y216 HydrophobicContact CB-CD2 3.96Å; A195-Y216 HydrophobicContact CB-CE1 3.81Å; A195-Y216 HydrophobicContact CB-CE2 3.71Å; A195-Y216 HydrophobicContact CB-CG 4.13Å; A195-Y216 PolarHBondContact N-OH 2.95Å
196A96.8Very high96.8Very high6 Ų647.9 Ų47.95%0.0525%0.248CC..THydrogen-bonded Turntrans-51.1132.9173.800000110.6F173 A176 P194 S198F173-A196 HydrophobicContact CB-CB 4.06Å; F173-A196 HydrophobicContact CD2-CB 3.72Å; F173-A196 HydrophobicContact CG-CB 4Å; A176-A196 PolarHBondContact N-O 3.23Å; P194-A196 PolarHBondContact O-N 3.06Å; A196-S198 VanDerWaalsContact C-N 3.32Å
197M95.4Very high96.9Very high55 Ų5551.7 Ų51.727%0.27128%0.275SS..THydrogen-bonded Turntrans77.13.1-177.2-48.7-81.1-65.300115.9F173 L175 A195 K199 A396 D397F173-M197 HydrophobicContact CE2-CG 3.82Å; F173-M197 HydrophobicContact CE2-SD 3.86Å; F173-M197 HydrophobicContact CZ-CG 4.28Å; F173-M197 HydrophobicContact CZ-SD 3.71Å; L175-M197 HydrophobicContact CD1-CB 3.75Å; L175-M197 HydrophobicContact CD1-CG 3.66Å; A195-M197 PolarHBondContact O-N 3.47Å; M197-K199 VanDerWaalsContact C-N 3.3Å; M197-K199 PolarHBondContact O-N 3.15Å; M197-A396 VanDerWaalsContact CE-C 3.41Å; M197-A396 WeakPolarHBondContact CE-O 3.29Å; M197-D397 WeakPolarHBondContact SD-CA 3.41Å; M197-D397 HydrophobicContact SD-CB 3.84Å
198S95.9Very high97Very high8 Ų853.3 Ų53.36%0.05628%0.279CS..SBendtrans-77.6-12.9178.164.40000114A195 A196 L200A195-S198 WeakPolarHBondContact O-CB 3.5Å; A195-S198 PolarHBondContact O-N 3.36Å; A195-S198 PolarHBondContact O-OG 2.98Å; A196-S198 VanDerWaalsContact C-N 3.32Å; S198-L200 PolarHBondContact O-N 3.04Å; S198-L200 WeakPolarHBondContact OG-CB 2.94Å; S198-L200 PolarHBondContact OG-N 2.91Å
199K96.5Very high97.1Very high118 Ų11857.6 Ų57.651%0.51329%0.292SS..  trans60.824.4-173.7-50.4-179.1-165.6-178.50113M197 P399 D400 V403M197-K199 VanDerWaalsContact C-N 3.3Å; M197-K199 PolarHBondContact O-N 3.15Å; K199-P399 HydrophobicContact CD-CB 4.12Å; K199-D400 VanDerWaalsContact CA-OD1 3.24Å; K199-D400 WeakPolarHBondContact CA-OD1 3.22Å; K199-D400 PolarHBondContact N-OD1 2.87Å; K199-V403 HydrophobicContact CB-CG2 4.15Å
200L97.7Very high97.2Very high17 Ų1759.8 Ų59.89%0.08930%0.302CS..  trans-96.4165.5175.3-65.8176.2000111.3P194 S198 M204 E208 Y211 N212P194-L200 HydrophobicContact CB-CB 3.73Å; S198-L200 PolarHBondContact O-N 3.04Å; S198-L200 WeakPolarHBondContact OG-CB 2.94Å; S198-L200 PolarHBondContact OG-N 2.91Å; L200-M204 HydrophobicContact CB-SD 4.32Å; L200-M204 HydrophobicContact CD1-SD 3.78Å; L200-E208 HydrophobicContact CD2-CB 4.05Å; L200-E208 HydrophobicContact CD2-CG 4.02Å; L200-Y211 HydrophobicContact CD1-CD1 3.78Å; L200-Y211 HydrophobicContact CD1-CE1 4.31Å; L200-Y211 HydrophobicContact CD2-CD1 4.39Å; L200-Y211 HydrophobicContact CG-CD1 4.26Å; L200-Y211 HydrophobicContact CG-CE1 4.49Å; L200-N212 HydrophobicContact CD1-CB 3.62Å
201T97.4Very high97.3Very high35 Ų3562.7 Ų62.722%0.21531%0.307CS..  trans-110.9175.5173.274.40000111.2K203 M204 F265 V403 A407T201-K203 PolarHBondContact O-N 3.34Å; T201-K203 PolarHBondContact OG1-N 3.46Å; T201-K203 PolarHBondContact OG1-O 3.14Å; T201-M204 VanDerWaalsContact O-CG 3.29Å; T201-M204 WeakPolarHBondContact O-CG 3.01Å; T201-F265 HydrophobicContact CG2-CE2 4.41Å; T201-F265 HydrophobicContact CG2-CZ 3.96Å; T201-V403 HydrophobicContact CG2-CG1 3.91Å; T201-A407 HydrophobicContact CG2-CB 3.87Å
202D96.3Very high97.4Very high49 Ų4959.7 Ų59.726%0.26229%0.286SS..SBendtrans-68.9-9.5171.764.1-22.3000114.1F192 F265F192-D202 VanDerWaalsContact O-CA 3.29Å; F192-D202 WeakPolarHBondContact O-CA 3.45Å; D202-F265 HydrophobicContact CB-CB 3.77Å; D202-F265 HydrophobicContact CB-CD1 3.98Å; D202-F265 HydrophobicContact CB-CD2 4.37Å; D202-F265 HydrophobicContact CB-CG 3.79Å; D202-F265 VanDerWaalsContact OD1-CD1 3.25Å; D202-F265 WeakPolarHBondContact OD1-CD1 3.48Å; D202-F265 WeakPolarHBondContact OD1-CE1 3.24Å
203K96.8Very high97.5Very high169 Ų16959.4 Ų59.474%0.73529%0.29SS*.SBendtrans-108.991.3176-63.6-178.5-174.7178.50110T201T201-K203 PolarHBondContact O-N 3.34Å; T201-K203 PolarHBondContact OG1-N 3.46Å; T201-K203 PolarHBondContact OG1-O 3.14Å
204M97.8Very high97.5Very high25 Ų2564.1 Ų64.112%0.12332%0.315CS..  trans-110.3137.5-178.9-68174.2-83.800112.3L200 T201 E208 R209 N212L200-M204 HydrophobicContact CB-SD 4.32Å; L200-M204 HydrophobicContact CD1-SD 3.78Å; T201-M204 VanDerWaalsContact O-CG 3.29Å; T201-M204 WeakPolarHBondContact O-CG 3.01Å; M204-E208 VanDerWaalsContact CA-OE2 3.31Å; M204-E208 WeakPolarHBondContact CA-OE2 3.36Å; M204-E208 HydrophobicContact CB-CB 3.74Å; M204-E208 HydrophobicContact CG-CB 3.93Å; M204-R209 HydrophobicContact CB-CG 3.56Å; M204-R209 HydrophobicContact CE-CG 4.49Å; M204-R209 HydrophobicContact SD-CG 4.29Å; M204-N212 HydrophobicContact SD-CB 3.85Å
205N97.8Very high97.4Very high84 Ų8464.3 Ų64.345%0.44932%0.315SS..  trans-74.7-178.5164.270.148.7000111.4S207 E208 R209N205-S207 WeakPolarHBondContact OD1-CB 3.38Å; N205-S207 PolarHBondContact OD1-N 3.49Å; N205-E208 PolarHBondContact N-OE2 2.92Å; N205-E208 PolarHBondContact ND2-OE2 3.43Å; N205-E208 PolarHBondContact O-N 3.43Å; N205-E208 PolarHBondContact OD1-N 2.62Å; N205-R209 WeakPolarHBondContact O-CB 3.19Å; N205-R209 VanDerWaalsContact O-CG 3.31Å; N205-R209 WeakPolarHBondContact O-CG 3.25Å; N205-R209 PolarHBondContact O-N 2.83Å
206F98.1Very high97.4Very high140 Ų14064.8 Ų64.861%0.61432%0.317SS*.Hα-helixtrans-61.7-46-178.6178.6-95.7000113.2E208 R209 L210F206-E208 VanDerWaalsContact C-N 3.34Å; F206-E208 PolarHBondContact O-N 3.24Å; F206-R209 PolarHBondContact O-N 2.98Å; F206-L210 HydrophobicContact CE1-CD2 4.49Å; F206-L210 WeakPolarHBondContact O-CB 3.45Å; F206-L210 PolarHBondContact O-N 2.97Å
207S98.4Very high97.4Very high85 Ų8567.1 Ų67.159%0.59434%0.336SS*.Hα-helixtrans-64.7-39.5-179.3-56.60000111.8N205 L210 Y211N205-S207 WeakPolarHBondContact OD1-CB 3.38Å; N205-S207 PolarHBondContact OD1-N 3.49Å; S207-L210 PolarHBondContact O-N 2.97Å; S207-Y211 WeakPolarHBondContact O-CB 3.45Å; S207-Y211 PolarHBondContact O-N 3.45Å
208E98.3Very high97.3Very high70 Ų7068.2 Ų68.233%0.32734%0.343SS..Hα-helixtrans-66.1-42174.9-71.1166.7156.800111.6L200 M204 N205 F206 Y211 N212L200-E208 HydrophobicContact CD2-CB 4.05Å; L200-E208 HydrophobicContact CD2-CG 4.02Å; M204-E208 VanDerWaalsContact CA-OE2 3.31Å; M204-E208 WeakPolarHBondContact CA-OE2 3.36Å; M204-E208 HydrophobicContact CB-CB 3.74Å; M204-E208 HydrophobicContact CG-CB 3.93Å; N205-E208 PolarHBondContact N-OE2 2.92Å; N205-E208 PolarHBondContact ND2-OE2 3.43Å; N205-E208 PolarHBondContact O-N 3.43Å; N205-E208 PolarHBondContact OD1-N 2.62Å; F206-E208 VanDerWaalsContact C-N 3.34Å; F206-E208 PolarHBondContact O-N 3.24Å; E208-Y211 PolarHBondContact O-N 2.93Å; E208-N212 WeakPolarHBondContact O-CB 3.36Å; E208-N212 PolarHBondContact O-N 2.93Å
209R98.5Very high97.3Very high103 Ų10368.2 Ų68.239%0.38934%0.342SS..Hα-helixtrans-63.7-40.8173.6-72.3-175.5-61.21672.9112.1S191 M204 N205 F206 N212 V213S191-R209 VanDerWaalsContact O-CD 3.3Å; S191-R209 WeakPolarHBondContact O-CD 3.28Å; M204-R209 HydrophobicContact CB-CG 3.56Å; M204-R209 HydrophobicContact CE-CG 4.49Å; M204-R209 HydrophobicContact SD-CG 4.29Å; N205-R209 WeakPolarHBondContact O-CB 3.19Å; N205-R209 VanDerWaalsContact O-CG 3.31Å; N205-R209 WeakPolarHBondContact O-CG 3.25Å; N205-R209 PolarHBondContact O-N 2.83Å; F206-R209 PolarHBondContact O-N 2.98Å; R209-N212 PolarHBondContact O-N 2.99Å; R209-V213 WeakPolarHBondContact O-CG2 3.26Å; R209-V213 PolarHBondContact O-N 3.07Å
210L98.4Very high97.2Very high87 Ų8764 Ų6446%0.45533%0.325SS..Hα-helixtrans-60.7-47.8174.8176.962000110.5F206 S207 N212 V213 L214F206-L210 HydrophobicContact CE1-CD2 4.49Å; F206-L210 WeakPolarHBondContact O-CB 3.45Å; F206-L210 PolarHBondContact O-N 2.97Å; S207-L210 PolarHBondContact O-N 2.97Å; L210-N212 VanDerWaalsContact C-N 3.34Å; L210-N212 PolarHBondContact O-N 2.81Å; L210-V213 PolarHBondContact O-N 3.27Å; L210-L214 HydrophobicContact CD1-CD1 4.21Å; L210-L214 HydrophobicContact CD1-CG 4.34Å; L210-L214 HydrophobicContact CG-CD1 4.19Å; L210-L214 WeakPolarHBondContact O-CG 3.13Å; L210-L214 PolarHBondContact O-N 3.34Å
211Y97.9Very high96.9Very high110 Ų11067.3 Ų67.343%0.43135%0.345SS..Hα-helixtrans-58.5-45.4174.6174.7-105.2000111.6L200 S207 E208 V213 L214 F215L200-Y211 HydrophobicContact CD1-CD1 3.78Å; L200-Y211 HydrophobicContact CD1-CE1 4.31Å; L200-Y211 HydrophobicContact CD2-CD1 4.39Å; L200-Y211 HydrophobicContact CG-CD1 4.26Å; L200-Y211 HydrophobicContact CG-CE1 4.49Å; S207-Y211 WeakPolarHBondContact O-CB 3.45Å; S207-Y211 PolarHBondContact O-N 3.45Å; E208-Y211 PolarHBondContact O-N 2.93Å; Y211-V213 PolarHBondContact O-N 3.05Å; Y211-L214 PolarHBondContact O-N 2.77Å; Y211-F215 HydrophobicContact CE1-CD2 4.37Å; Y211-F215 HydrophobicContact CE2-CD2 4.43Å; Y211-F215 AromaticContact CZ-CD2 3.85Å; Y211-F215 VanDerWaalsContact O-CB 3.26Å; Y211-F215 WeakPolarHBondContact O-CB 3.4Å; Y211-F215 PolarHBondContact O-N 3.42Å; Y211-F215 WeakPolarHBondContact OH-CD2 3.49Å
212N98.3Very high96.6Very high0 Ų066.6 Ų66.60%034%0.341CS..Hα-helixtrans-58.7-46.9179-162.938.2000111.8P190 V193 A195 L200 M204 E208 R209 L210 F215 Y216P190-N212 PolarHBondContact O-ND2 3.48Å; V193-N212 PolarHBondContact O-ND2 3.49Å; A195-N212 WeakPolarHBondContact CB-OD1 3.36Å; A195-N212 PolarHBondContact N-OD1 3.32Å; L200-N212 HydrophobicContact CD1-CB 3.62Å; M204-N212 HydrophobicContact SD-CB 3.85Å; E208-N212 WeakPolarHBondContact O-CB 3.36Å; E208-N212 PolarHBondContact O-N 2.93Å; R209-N212 PolarHBondContact O-N 2.99Å; L210-N212 VanDerWaalsContact C-N 3.34Å; L210-N212 PolarHBondContact O-N 2.81Å; N212-F215 PolarHBondContact O-N 3.33Å; N212-Y216 WeakPolarHBondContact O-CD2 3.46Å; N212-Y216 PolarHBondContact O-N 3.34Å
213V98.1Very high96.3Very high71 Ų7164.6 Ų64.643%0.4333%0.33SS..Hα-helixtrans-60.2-47.1176.6170.10000111.3P190 R209 L210 Y211 F215 Y216 A217P190-V213 HydrophobicContact CB-CG2 3.82Å; P190-V213 HydrophobicContact CG-CG2 3.99Å; R209-V213 WeakPolarHBondContact O-CG2 3.26Å; R209-V213 PolarHBondContact O-N 3.07Å; L210-V213 PolarHBondContact O-N 3.27Å; Y211-V213 PolarHBondContact O-N 3.05Å; V213-F215 VanDerWaalsContact C-N 3.31Å; V213-F215 PolarHBondContact O-N 2.93Å; V213-Y216 PolarHBondContact O-N 2.83Å; V213-A217 PolarHBondContact O-N 3.41Å; V213-A217 VanDerWaalsContact O-N 3.08Å
214L97.5Very high96Very high105 Ų10559.3 Ų59.355%0.5531%0.312SS..Hα-helixtrans-65.5-36.6178.2-67.8176.1000111.9L210 Y211 A217 L218L210-L214 HydrophobicContact CD1-CD1 4.21Å; L210-L214 HydrophobicContact CD1-CG 4.34Å; L210-L214 HydrophobicContact CG-CD1 4.19Å; L210-L214 WeakPolarHBondContact O-CG 3.13Å; L210-L214 PolarHBondContact O-N 3.34Å; Y211-L214 PolarHBondContact O-N 2.77Å; L214-A217 PolarHBondContact O-N 3.13Å; L214-L218 VanDerWaalsContact O-CB 3.29Å; L214-L218 WeakPolarHBondContact O-CB 3.38Å; L214-L218 PolarHBondContact O-N 3.03Å
215F96.6Very high95.4Very high14 Ų1463 Ų636%0.06133%0.329CS..Hα-helixtrans-65.7-47.7177.4-169.3-89.2000111L175 A176 A195 Y211 N212 V213 A217 L218 Q219L175-F215 HydrophobicContact CD1-CZ 4.49Å; A176-F215 HydrophobicContact CB-CD1 4.35Å; A176-F215 HydrophobicContact CB-CE1 4.3Å; A195-F215 HydrophobicContact CB-CD1 3.55Å; A195-F215 HydrophobicContact CB-CE1 4.07Å; Y211-F215 HydrophobicContact CE1-CD2 4.37Å; Y211-F215 HydrophobicContact CE2-CD2 4.43Å; Y211-F215 AromaticContact CZ-CD2 3.85Å; Y211-F215 VanDerWaalsContact O-CB 3.26Å; Y211-F215 WeakPolarHBondContact O-CB 3.4Å; Y211-F215 PolarHBondContact O-N 3.42Å; Y211-F215 WeakPolarHBondContact OH-CD2 3.49Å; N212-F215 PolarHBondContact O-N 3.33Å; V213-F215 VanDerWaalsContact C-N 3.31Å; V213-F215 PolarHBondContact O-N 2.93Å; F215-A217 PolarHBondContact O-N 2.83Å; F215-L218 PolarHBondContact O-N 2.79Å; F215-Q219 HydrophobicContact CD1-CG 3.8Å; F215-Q219 HydrophobicContact CE1-CG 3.54Å; F215-Q219 HydrophobicContact CE2-CG 4.47Å; F215-Q219 HydrophobicContact CG-CG 4.4Å; F215-Q219 HydrophobicContact CZ-CG 3.9Å; F215-Q219 WeakPolarHBondContact O-CB 3.32Å; F215-Q219 VanDerWaalsContact O-CG 3.28Å; F215-Q219 WeakPolarHBondContact O-CG 3.31Å; F215-Q219 PolarHBondContact O-N 3.26Å
216Y97.5Very high94.7Very high10 Ų1063.1 Ų63.14%0.03933%0.326CS..Hα-helixtrans-53.2-52.8171.9-84.1-69.7000111.4A176 P190 V193 P194 A195 N212 V213 L218 Q219 D220A176-Y216 HydrophobicContact CB-CD1 3.87Å; A176-Y216 HydrophobicContact CB-CE1 4.26Å; A176-Y216 WeakPolarHBondContact O-CD1 3.07Å; A176-Y216 WeakPolarHBondContact O-CE1 3.46Å; P190-Y216 HydrophobicContact CB-CD2 3.77Å; P190-Y216 HydrophobicContact CB-CE2 3.8Å; V193-Y216 PolarHBondContact O-OH 2.89Å; P194-Y216 PolarHBondContact O-OH 3.45Å; A195-Y216 WeakPolarHBondContact CA-OH 3.2Å; A195-Y216 HydrophobicContact CB-CD1 4.05Å; A195-Y216 HydrophobicContact CB-CD2 3.96Å; A195-Y216 HydrophobicContact CB-CE1 3.81Å; A195-Y216 HydrophobicContact CB-CE2 3.71Å; A195-Y216 HydrophobicContact CB-CG 4.13Å; A195-Y216 PolarHBondContact N-OH 2.95Å; N212-Y216 WeakPolarHBondContact O-CD2 3.46Å; N212-Y216 PolarHBondContact O-N 3.34Å; V213-Y216 PolarHBondContact O-N 2.83Å; Y216-L218 PolarHBondContact O-N 3.27Å; Y216-Q219 PolarHBondContact O-N 3.32Å; Y216-D220 WeakPolarHBondContact O-CB 3.17Å; Y216-D220 PolarHBondContact O-N 3.49Å
217A96.1Very high94Very high54 Ų5458.9 Ų58.945%0.44631%0.309SS..Hα-helixtrans-60.6-43.5-177.800000112.5V213 L214 F215 V221V213-A217 PolarHBondContact O-N 3.41Å; V213-A217 VanDerWaalsContact O-N 3.08Å; L214-A217 PolarHBondContact O-N 3.13Å; F215-A217 PolarHBondContact O-N 2.83Å; A217-V221 WeakPolarHBondContact O-CG2 3.3Å; A217-V221 PolarHBondContact O-N 3.49Å
218L94.2Very high93.6Very high79 Ų7955.2 Ų55.241%0.41428%0.282SS..Hα-helixtrans-64.1-47.1177.8178.860.8000111.4Y108 L214 F215 Y216 D220 V221 V222Y108-L218 HydrophobicContact CE1-CD2 3.97Å; Y108-L218 HydrophobicContact CE1-CG 4.48Å; Y108-L218 HydrophobicContact CE2-CD2 4.3Å; L214-L218 VanDerWaalsContact O-CB 3.29Å; L214-L218 WeakPolarHBondContact O-CB 3.38Å; L214-L218 PolarHBondContact O-N 3.03Å; F215-L218 PolarHBondContact O-N 2.79Å; Y216-L218 PolarHBondContact O-N 3.27Å; L218-D220 PolarHBondContact O-N 3.2Å; L218-V221 PolarHBondContact O-N 2.83Å; L218-V222 HydrophobicContact CD1-CG2 4.15Å; L218-V222 HydrophobicContact CG-CG2 4.45Å; L218-V222 WeakPolarHBondContact O-CG2 3.21Å; L218-V222 PolarHBondContact O-N 3.27Å
219Q94.4Very high93.2Very high8 Ų858 Ų584%0.03729%0.293CS..Hα-helixtrans-65.9-38.3179.9-64.6-50.7-25.800112.1Y108 L175 A176 F215 Y216 V221 V222 I223Y108-Q219 PolarHBondContact OH-NE2 2.51Å; L175-Q219 HydrophobicContact CD2-CG 4.35Å; L175-Q219 HydrophobicContact CG-CB 4.45Å; L175-Q219 HydrophobicContact CG-CG 4.1Å; A176-Q219 HydrophobicContact CB-CB 3.64Å; A176-Q219 HydrophobicContact CB-CG 3.9Å; F215-Q219 HydrophobicContact CD1-CG 3.8Å; F215-Q219 HydrophobicContact CE1-CG 3.54Å; F215-Q219 HydrophobicContact CE2-CG 4.47Å; F215-Q219 HydrophobicContact CG-CG 4.4Å; F215-Q219 HydrophobicContact CZ-CG 3.9Å; F215-Q219 WeakPolarHBondContact O-CB 3.32Å; F215-Q219 VanDerWaalsContact O-CG 3.28Å; F215-Q219 WeakPolarHBondContact O-CG 3.31Å; F215-Q219 PolarHBondContact O-N 3.26Å; Y216-Q219 PolarHBondContact O-N 3.32Å; Q219-V221 VanDerWaalsContact C-N 3.31Å; Q219-V221 PolarHBondContact O-N 3.29Å; Q219-V222 PolarHBondContact O-N 3.41Å; Q219-I223 HydrophobicContact CB-CD1 4.29Å; Q219-I223 VanDerWaalsContact O-CB 3.32Å; Q219-I223 WeakPolarHBondContact O-CB 3.41Å; Q219-I223 WeakPolarHBondContact O-CD1 3.5Å; Q219-I223 WeakPolarHBondContact O-CG1 3.4Å; Q219-I223 PolarHBondContact O-N 2.72Å
220D94.5Very high92.9Very high29 Ų2956 Ų5616%0.15529%0.29CS..Hα-helixtrans-59.3-43176.1-69.7-11000111.3H178 R181 Y216 L218 T224H178-D220 IonicContact CD2-OD1 2.69Å; H178-D220 PolarHBondContact CD2-OD1 3.38Å; R181-D220 IonicContact CZ-OD2 2.74Å; R181-D220 IonicContact NH2-OD1 3.74Å; R181-D220 PolarHBondContact NH2-OD1 3.1Å; R181-D220 IonicContact NH2-OD2 3.11Å; R181-D220 PolarHBondContact NH2-OD2 3.15Å; Y216-D220 WeakPolarHBondContact O-CB 3.17Å; Y216-D220 PolarHBondContact O-N 3.49Å; L218-D220 PolarHBondContact O-N 3.2Å; D220-T224 VanDerWaalsContact O-CB 3.26Å; D220-T224 WeakPolarHBondContact O-CB 3.41Å; D220-T224 PolarHBondContact O-N 3.22Å; D220-T224 VanDerWaalsContact O-N 3.13Å; D220-T224 PolarHBondContact O-OG1 3.13Å
221V92.5Very high92.7Very high87 Ų8752 Ų5253%0.52727%0.27SS..Hα-helixtrans-65.2-48.9174.7172.90000111A217 L218 Q219 I223 T224 Q225A217-V221 WeakPolarHBondContact O-CG2 3.3Å; A217-V221 PolarHBondContact O-N 3.49Å; L218-V221 PolarHBondContact O-N 2.83Å; Q219-V221 VanDerWaalsContact C-N 3.31Å; Q219-V221 PolarHBondContact O-N 3.29Å; V221-I223 PolarHBondContact O-N 3.27Å; V221-T224 PolarHBondContact O-N 3.2Å; V221-Q225 HydrophobicContact CG1-CG 4.22Å; V221-Q225 WeakPolarHBondContact O-CB 3.39Å; V221-Q225 VanDerWaalsContact O-CG 3.27Å; V221-Q225 WeakPolarHBondContact O-CG 3.3Å; V221-Q225 PolarHBondContact O-N 3.31Å
222V89.8Confident92.6Very high19 Ų1948.5 Ų48.512%0.11526%0.258CS..Hα-helixtrans-62.1-48.3-176169.40000111.2I112 L218 Q219 Q225 F226I112-V222 HydrophobicContact CG1-CG1 4.36Å; L218-V222 HydrophobicContact CD1-CG2 4.15Å; L218-V222 HydrophobicContact CG-CG2 4.45Å; L218-V222 WeakPolarHBondContact O-CG2 3.21Å; L218-V222 PolarHBondContact O-N 3.27Å; Q219-V222 PolarHBondContact O-N 3.41Å; V222-Q225 PolarHBondContact O-N 2.96Å; V222-F226 HydrophobicContact CB-CD2 4.49Å; V222-F226 HydrophobicContact CG1-CD2 4.23Å; V222-F226 WeakPolarHBondContact O-CB 3.44Å; V222-F226 WeakPolarHBondContact O-CD2 3.43Å; V222-F226 PolarHBondContact O-N 2.8Å
223I90.9Very high92.4Very high7 Ų754.6 Ų54.64%0.03629%0.285CS..Hα-helixtrans-62.5-47.8-179.5-67.4165000110.1L175 H178 Q219 V221 Q225 M227 L228L175-I223 HydrophobicContact CB-CD1 3.96Å; L175-I223 HydrophobicContact CD2-CD1 4.3Å; L175-I223 HydrophobicContact CG-CD1 4.26Å; H178-I223 HydrophobicContact CB-CD1 3.53Å; Q219-I223 HydrophobicContact CB-CD1 4.29Å; Q219-I223 VanDerWaalsContact O-CB 3.32Å; Q219-I223 WeakPolarHBondContact O-CB 3.41Å; Q219-I223 WeakPolarHBondContact O-CD1 3.5Å; Q219-I223 WeakPolarHBondContact O-CG1 3.4Å; Q219-I223 PolarHBondContact O-N 2.72Å; V221-I223 PolarHBondContact O-N 3.27Å; I223-Q225 PolarHBondContact O-N 2.79Å; I223-M227 HydrophobicContact CG1-SD 4.04Å; I223-M227 WeakPolarHBondContact O-CA 3.36Å; I223-M227 WeakPolarHBondContact O-CB 3.41Å; I223-M227 PolarHBondContact O-N 3.36Å; I223-L228 HydrophobicContact CG2-CD1 3.96Å; I223-L228 HydrophobicContact CG2-CG 3.87Å; I223-L228 PolarHBondContact O-N 2.76Å
224T89.5Confident92.3Very high59 Ų5951.8 Ų51.836%0.36227%0.266SS..Iπ-helixtrans-63.2-44.7-178.9-57.90000111.9D220 V221 K229D220-T224 VanDerWaalsContact O-CB 3.26Å; D220-T224 WeakPolarHBondContact O-CB 3.41Å; D220-T224 PolarHBondContact O-N 3.22Å; D220-T224 VanDerWaalsContact O-N 3.13Å; D220-T224 PolarHBondContact O-OG1 3.13Å; V221-T224 PolarHBondContact O-N 3.2Å; T224-K229 PolarHBondContact O-N 3.44Å
225Q85.8Confident92.2Very high102 Ų10246.8 Ų46.848%0.47724%0.24SC..Iπ-helixtrans-84.1-32.8-172.1-62.3-56.2-4400114.1V221 V222 I223V221-Q225 HydrophobicContact CG1-CG 4.22Å; V221-Q225 WeakPolarHBondContact O-CB 3.39Å; V221-Q225 VanDerWaalsContact O-CG 3.27Å; V221-Q225 WeakPolarHBondContact O-CG 3.3Å; V221-Q225 PolarHBondContact O-N 3.31Å; V222-Q225 PolarHBondContact O-N 2.96Å; I223-Q225 PolarHBondContact O-N 2.79Å
226F82.4Confident92.3Very high86 Ų8647.5 Ų47.538%0.37725%0.247SC..Iπ-helixtrans-114.5-13.3-171.7-59.6-73000114.8I112 V222I112-F226 HydrophobicContact CG2-CG 4.47Å; V222-F226 HydrophobicContact CB-CD2 4.49Å; V222-F226 HydrophobicContact CG1-CD2 4.23Å; V222-F226 WeakPolarHBondContact O-CB 3.44Å; V222-F226 WeakPolarHBondContact O-CD2 3.43Å; V222-F226 PolarHBondContact O-N 2.8Å
227M83.8Confident92.2Very high52 Ų5252.4 Ų52.426%0.25627%0.27SS..Iπ-helixtrans-114.8-55.3178.3-58.5-179.566.600111.9T115 M119 I223 K229T115-M227 HydrophobicContact CG2-CE 3.62Å; T115-M227 HydrophobicContact CG2-CG 3.8Å; T115-M227 HydrophobicContact CG2-SD 3.83Å; M119-M227 HydrophobicContact CE-CB 4.18Å; M119-M227 HydrophobicContact CE-CE 4.38Å; I223-M227 HydrophobicContact CG1-SD 4.04Å; I223-M227 WeakPolarHBondContact O-CA 3.36Å; I223-M227 WeakPolarHBondContact O-CB 3.41Å; I223-M227 PolarHBondContact O-N 3.36Å; M227-K229 PolarHBondContact O-N 2.88Å
228L89.9Confident92.2Very high8 Ų852.1 Ų52.14%0.04226%0.263CS..Iπ-helixtrans-75.5-26-172.9-63.3-175.9000113.2I223 D230 I231 D232 N245I223-L228 HydrophobicContact CG2-CD1 3.96Å; I223-L228 HydrophobicContact CG2-CG 3.87Å; I223-L228 PolarHBondContact O-N 2.76Å; L228-D230 VanDerWaalsContact C-N 3.33Å; L228-D230 PolarHBondContact O-N 3.13Å; L228-I231 HydrophobicContact CD2-CD1 4.24Å; L228-I231 PolarHBondContact O-N 3.04Å; L228-D232 WeakPolarHBondContact O-CB 3.34Å; L228-D232 VanDerWaalsContact O-CG 3.23Å; L228-D232 PolarHBondContact O-N 2.94Å; L228-N245 HydrophobicContact CD2-CB 4.37Å
229K91.3Very high92.2Very high127 Ų12752.1 Ų52.155%0.55226%0.259SS*.Hα-helixtrans-56.7-43.6-178.5-172.4179.1179.9179.80113.4T224 M227 K233T224-K229 PolarHBondContact O-N 3.44Å; M227-K229 PolarHBondContact O-N 2.88Å; K229-K233 WeakPolarHBondContact O-CB 3.47Å; K229-K233 PolarHBondContact O-N 3.46Å
230D91.7Very high92.3Very high61 Ų6154.9 Ų54.933%0.32629%0.29SS..Hα-helixtrans-73.3-35.4-179.8-65.4-35.2000111.4L123 L228 Y234L123-D230 HydrophobicContact CD1-CB 4.36Å; L228-D230 VanDerWaalsContact C-N 3.33Å; L228-D230 PolarHBondContact O-N 3.13Å; D230-Y234 WeakPolarHBondContact O-CB 3.31Å; D230-Y234 PolarHBondContact O-N 3.3Å
231I93.9Very high92.3Very high5 Ų557.2 Ų57.23%0.02631%0.306CS..Hα-helixtrans-64.7-47.9172.8-61.7176.3000110.6M119 P154 L228 K233 Y234 Y235 N245M119-I231 HydrophobicContact CE-CD1 3.52Å; M119-I231 HydrophobicContact CE-CG1 4.04Å; M119-I231 HydrophobicContact SD-CD1 3.68Å; M119-I231 HydrophobicContact SD-CG1 3.69Å; P154-I231 HydrophobicContact CB-CD1 4.19Å; L228-I231 HydrophobicContact CD2-CD1 4.24Å; L228-I231 PolarHBondContact O-N 3.04Å; I231-K233 VanDerWaalsContact C-N 3.31Å; I231-K233 PolarHBondContact O-N 2.9Å; I231-Y234 WeakPolarHBondContact O-CB 3.47Å; I231-Y234 PolarHBondContact O-N 3.47Å; I231-Y235 HydrophobicContact CG2-CD1 3.65Å; I231-Y235 HydrophobicContact CG2-CD2 4.37Å; I231-Y235 HydrophobicContact CG2-CE1 3.36Å; I231-Y235 HydrophobicContact CG2-CE2 4.11Å; I231-Y235 HydrophobicContact CG2-CG 4.18Å; I231-Y235 WeakPolarHBondContact O-CB 3.3Å; I231-Y235 WeakPolarHBondContact O-CD1 3.49Å; I231-Y235 PolarHBondContact O-N 3.3Å; I231-N245 HydrophobicContact CG2-CB 3.82Å
232D95.2Very high92.4Very high35 Ų3558.8 Ų58.819%0.18732%0.318CS..Hα-helixtrans-60.7-42-179.7-74.2-3000111.2L228 S236 T244 N245L228-D232 WeakPolarHBondContact O-CB 3.34Å; L228-D232 VanDerWaalsContact O-CG 3.23Å; L228-D232 PolarHBondContact O-N 2.94Å; D232-S236 VanDerWaalsContact O-CB 3.3Å; D232-S236 WeakPolarHBondContact O-CB 3.4Å; D232-S236 PolarHBondContact O-N 3.32Å; D232-S236 PolarHBondContact O-OG 2.85Å; D232-T244 VanDerWaalsContact OD1-CA 3.3Å; D232-T244 WeakPolarHBondContact OD1-CA 3.47Å; D232-T244 WeakPolarHBondContact OD2-CB 3.3Å; D232-T244 WeakPolarHBondContact OD2-CG2 3.4Å; D232-N245 WeakPolarHBondContact OD1-CB 3.33Å; D232-N245 PolarHBondContact OD1-N 3.43Å
233K95.1Very high92.6Very high129 Ų12958.5 Ų58.556%0.56132%0.316SS*.Hα-helixtrans-60.3-52.3173.5-177.9-177.1173-171.20110.6K229 I231 Y235 S236 E237K229-K233 WeakPolarHBondContact O-CB 3.47Å; K229-K233 PolarHBondContact O-N 3.46Å; I231-K233 VanDerWaalsContact C-N 3.31Å; I231-K233 PolarHBondContact O-N 2.9Å; K233-Y235 VanDerWaalsContact C-N 3.34Å; K233-Y235 PolarHBondContact O-N 3.28Å; K233-S236 PolarHBondContact O-N 2.96Å; K233-E237 WeakPolarHBondContact CE-OE1 3.46Å; K233-E237 WeakPolarHBondContact O-CG 3.47Å; K233-E237 PolarHBondContact O-N 3.22Å
234Y95.8Very high92.7Very high11 Ų1161 Ų614%0.04333%0.331CS..Hα-helixtrans-58-45.6179.3-174.9-77.3000111.9L123 L126 D127 V130 L158 D230 I231 S236 E237 V238L123-Y234 HydrophobicContact CB-CD2 4.49Å; L123-Y234 HydrophobicContact CD2-CD2 3.93Å; L123-Y234 HydrophobicContact CD2-CE2 4.47Å; L123-Y234 HydrophobicContact CD2-CG 3.98Å; L126-Y234 HydrophobicContact CD2-CD1 3.81Å; L126-Y234 HydrophobicContact CD2-CE1 3.4Å; L126-Y234 VanDerWaalsContact CD2-CE1 3.4Å; L126-Y234 HydrophobicContact CG-CE1 3.67Å; D127-Y234 PolarHBondContact N-OH 2.92Å; D127-Y234 WeakPolarHBondContact OD1-CE2 3.35Å; D127-Y234 VanDerWaalsContact OD1-CZ 3.23Å; D127-Y234 PolarHBondContact OD1-OH 2.94Å; V130-Y234 HydrophobicContact CG2-CE1 3.76Å; V130-Y234 WeakPolarHBondContact CG2-OH 3.32Å; L158-Y234 HydrophobicContact CD2-CE1 4.45Å; D230-Y234 WeakPolarHBondContact O-CB 3.31Å; D230-Y234 PolarHBondContact O-N 3.3Å; I231-Y234 WeakPolarHBondContact O-CB 3.47Å; I231-Y234 PolarHBondContact O-N 3.47Å; Y234-S236 VanDerWaalsContact C-N 3.33Å; Y234-S236 PolarHBondContact O-N 2.78Å; Y234-E237 WeakPolarHBondContact O-CB 3.39Å; Y234-E237 PolarHBondContact O-N 3.39Å; Y234-V238 HydrophobicContact CD1-CG2 3.97Å; Y234-V238 HydrophobicContact CE1-CG2 3.58Å; Y234-V238 WeakPolarHBondContact O-CG2 3.24Å; Y234-V238 PolarHBondContact O-N 2.85Å
235Y96.4Very high92.9Very high0 Ų058.3 Ų58.30%032%0.315CS..Hα-helixtrans-65.5-40.4-178.6-78.428.2000110.7L126 G155 D157 L158 I231 K233 V238 K239 V243 N245 M248L126-Y235 HydrophobicContact CD2-CE1 3.99Å; G155-Y235 WeakPolarHBondContact CA-OH 3.48Å; G155-Y235 PolarHBondContact N-OH 3.09Å; D157-Y235 WeakPolarHBondContact OD1-CE2 3.49Å; D157-Y235 PolarHBondContact OD1-OH 3.31Å; D157-Y235 WeakPolarHBondContact OD2-CE2 3.5Å; L158-Y235 HydrophobicContact CB-CD1 4.49Å; L158-Y235 HydrophobicContact CB-CD2 4.09Å; L158-Y235 HydrophobicContact CB-CE1 4.17Å; L158-Y235 HydrophobicContact CB-CE2 3.76Å; L158-Y235 HydrophobicContact CB-CG 4.44Å; L158-Y235 HydrophobicContact CD2-CD1 3.79Å; L158-Y235 HydrophobicContact CD2-CE1 3.99Å; L158-Y235 HydrophobicContact CD2-CG 4.07Å; I231-Y235 HydrophobicContact CG2-CD1 3.65Å; I231-Y235 HydrophobicContact CG2-CD2 4.37Å; I231-Y235 HydrophobicContact CG2-CE1 3.36Å; I231-Y235 HydrophobicContact CG2-CE2 4.11Å; I231-Y235 HydrophobicContact CG2-CG 4.18Å; I231-Y235 WeakPolarHBondContact O-CB 3.3Å; I231-Y235 WeakPolarHBondContact O-CD1 3.49Å; I231-Y235 PolarHBondContact O-N 3.3Å; K233-Y235 VanDerWaalsContact C-N 3.34Å; K233-Y235 PolarHBondContact O-N 3.28Å; Y235-V238 PolarHBondContact O-N 2.98Å; Y235-K239 WeakPolarHBondContact O-CB 3.34Å; Y235-K239 VanDerWaalsContact O-CG 3.28Å; Y235-K239 WeakPolarHBondContact O-CG 3.33Å; Y235-K239 PolarHBondContact O-N 3.46Å; Y235-V243 HydrophobicContact CD2-CG1 4.4Å; Y235-N245 HydrophobicContact CE2-CB 4.36Å; Y235-M248 HydrophobicContact CD2-CG 4.01Å; Y235-M248 HydrophobicContact CE2-CG 4.17Å
236S96.8Very high93.1Very high30 Ų3054.6 Ų54.621%0.2130%0.3CS..Hα-helixtrans-63.9-40.2175.6-61.60000112.1D232 K233 Y234 K239 G240 T241 V243D232-S236 VanDerWaalsContact O-CB 3.3Å; D232-S236 WeakPolarHBondContact O-CB 3.4Å; D232-S236 PolarHBondContact O-N 3.32Å; D232-S236 PolarHBondContact O-OG 2.85Å; K233-S236 PolarHBondContact O-N 2.96Å; Y234-S236 VanDerWaalsContact C-N 3.33Å; Y234-S236 PolarHBondContact O-N 2.78Å; S236-K239 PolarHBondContact O-N 3.38Å; S236-G240 WeakPolarHBondContact O-CA 3.44Å; S236-G240 PolarHBondContact O-N 3.05Å; S236-T241 WeakPolarHBondContact CA-O 3.26Å; S236-T241 PolarHBondContact O-N 2.95Å; S236-V243 PolarHBondContact OG-N 2.91Å; S236-V243 PolarHBondContact OG-O 3.44Å
237E96.6Very high93.6Very high113 Ų11355.9 Ų55.953%0.52831%0.305SS..Hα-helixtrans-62-48.4175.4-74.2172.9-176.400111.5K233 Y234 K239 G240K233-E237 WeakPolarHBondContact CE-OE1 3.46Å; K233-E237 WeakPolarHBondContact O-CG 3.47Å; K233-E237 PolarHBondContact O-N 3.22Å; Y234-E237 WeakPolarHBondContact O-CB 3.39Å; Y234-E237 PolarHBondContact O-N 3.39Å; E237-K239 PolarHBondContact O-N 3.38Å; E237-G240 PolarHBondContact O-N 3.45Å
238V95.7Very high94Very high47 Ų4753.9 Ų53.929%0.28530%0.296SS..Hα-helixtrans-65-391791740000111.9V130 L158 I162 Y234 Y235V130-V238 HydrophobicContact CG2-CG2 4.22Å; L158-V238 HydrophobicContact CD2-CB 4.17Å; L158-V238 HydrophobicContact CD2-CG1 4.1Å; L158-V238 HydrophobicContact CD2-CG2 4.42Å; I162-V238 HydrophobicContact CD1-CG1 4.08Å; Y234-V238 HydrophobicContact CD1-CG2 3.97Å; Y234-V238 HydrophobicContact CE1-CG2 3.58Å; Y234-V238 WeakPolarHBondContact O-CG2 3.24Å; Y234-V238 PolarHBondContact O-N 2.85Å; Y235-V238 PolarHBondContact O-N 2.98Å
239K94.8Very high94.2Very high79 Ų7953.5 Ų53.534%0.34329%0.294SS..Hα-helixtrans-78.4-19.2179.9-70.7-72.2-62.8-1720113.4L158 D161 Y235 S236 E237 T241 V243 M248L158-K239 HydrophobicContact CD1-CD 3.89Å; L158-K239 HydrophobicContact CD1-CG 3.84Å; D161-K239 WeakPolarHBondContact OD2-CE 2.95Å; D161-K239 IonicContact OD2-NZ 3.61Å; D161-K239 PolarHBondContact OD2-NZ 3.03Å; Y235-K239 WeakPolarHBondContact O-CB 3.34Å; Y235-K239 VanDerWaalsContact O-CG 3.28Å; Y235-K239 WeakPolarHBondContact O-CG 3.33Å; Y235-K239 PolarHBondContact O-N 3.46Å; S236-K239 PolarHBondContact O-N 3.38Å; E237-K239 PolarHBondContact O-N 3.38Å; K239-T241 PolarHBondContact O-N 3.21Å; K239-V243 HydrophobicContact CG-CG1 4.42Å; K239-M248 HydrophobicContact CD-CE 4.24Å; K239-M248 HydrophobicContact CG-CE 4.23Å
240G95.3Very high94.2Very high67 Ų6752 Ų5269%0.69129%0.285SS*.THydrogen-bonded Turntrans68.68.4-170.600000114.4S236 E237S236-G240 WeakPolarHBondContact O-CA 3.44Å; S236-G240 PolarHBondContact O-N 3.05Å; E237-G240 PolarHBondContact O-N 3.45Å
241T94.7Very high94.1Very high78 Ų7853.2 Ų53.248%0.47929%0.291SS..SBendtrans-143.7147.5-179.4610000110.4S236 K239 V243S236-T241 WeakPolarHBondContact CA-O 3.26Å; S236-T241 PolarHBondContact O-N 2.95Å; K239-T241 PolarHBondContact O-N 3.21Å; T241-V243 PolarHBondContact O-N 3.49Å
242P95.5Very high94.2Very high119 Ų11953.3 Ų53.377%0.77329%0.292SS*.  trans-56120.5177.8-25.934.9000112.9
243V94.6Very high94.4Very high13 Ų1352.5 Ų52.58%0.07929%0.288CS..  trans-144.8149.9177.4109.20000109.6Y235 S236 K239 T241 K247 M248Y235-V243 HydrophobicContact CD2-CG1 4.4Å; S236-V243 PolarHBondContact OG-N 2.91Å; S236-V243 PolarHBondContact OG-O 3.44Å; K239-V243 HydrophobicContact CG-CG1 4.42Å; T241-V243 PolarHBondContact O-N 3.49Å; V243-K247 HydrophobicContact CG2-CD 4.04Å; V243-M248 HydrophobicContact CB-CE 4.35Å; V243-M248 HydrophobicContact CG1-CE 3.6Å; V243-M248 HydrophobicContact CG1-SD 4.49Å; V243-M248 HydrophobicContact CG2-CE 3.87Å; V243-M248 HydrophobicContact CG2-SD 4.23Å
244T92.8Very high94.5Very high59 Ų5946.4 Ų46.436%0.36226%0.261SS..  trans-115.6150.8175.265.80000110.3D232 C246 K247 M248D232-T244 VanDerWaalsContact OD1-CA 3.3Å; D232-T244 WeakPolarHBondContact OD1-CA 3.47Å; D232-T244 WeakPolarHBondContact OD2-CB 3.3Å; D232-T244 WeakPolarHBondContact OD2-CG2 3.4Å; T244-C246 VanDerWaalsContact C-N 3.3Å; T244-C246 PolarHBondContact O-N 3.34Å; T244-K247 WeakPolarHBondContact O-CB 3.37Å; T244-K247 PolarHBondContact O-N 3.01Å; T244-K247 WeakPolarHBondContact OG1-CB 3.43Å; T244-K247 PolarHBondContact OG1-N 3.03Å; T244-M248 PolarHBondContact O-N 3.49Å; T244-M248 VanDerWaalsContact O-N 3.16Å
245N91.9Very high94.7Very high4 Ų446 Ų462%0.02126%0.259CS..Hα-helixtrans-56.6-44.8173.4171.8-106.4000111D157 L228 I231 D232 Y235 K247 M248 L249D157-N245 PolarHBondContact OD2-ND2 3.31Å; L228-N245 HydrophobicContact CD2-CB 4.37Å; I231-N245 HydrophobicContact CG2-CB 3.82Å; D232-N245 WeakPolarHBondContact OD1-CB 3.33Å; D232-N245 PolarHBondContact OD1-N 3.43Å; Y235-N245 HydrophobicContact CE2-CB 4.36Å; N245-K247 PolarHBondContact O-N 2.89Å; N245-M248 WeakPolarHBondContact O-CA 3.33Å; N245-M248 WeakPolarHBondContact O-CB 3.27Å; N245-M248 PolarHBondContact O-N 3.09Å; N245-L249 WeakPolarHBondContact O-CG 3.38Å; N245-L249 PolarHBondContact O-N 3.1Å; N245-L249 WeakPolarHBondContact OD1-CD1 3.26Å
246C91.9Very high94.8Very high24 Ų2446 Ų4616%0.16226%0.259CS..Hα-helixtrans-58.5-36.5175.3-112.30000112.2C183 T244 M248 L249 R250C183-C246 HydrophobicContact CB-CB 3.95Å; C183-C246 WeakPolarHBondContact CB-SG 3.47Å; C183-C246 WeakPolarHBondContact SG-CA 3.36Å; C183-C246 WeakPolarHBondContact SG-CB 3.21Å; C183-C246 CovalentContact SG-SG 2.05Å; C183-C246 PolarHBondContact SG-SG 2.82Å; T244-C246 VanDerWaalsContact C-N 3.3Å; T244-C246 PolarHBondContact O-N 3.34Å; C246-M248 VanDerWaalsContact C-N 3.33Å; C246-L249 PolarHBondContact O-N 2.82Å; C246-R250 WeakPolarHBondContact O-CG 3.45Å; C246-R250 PolarHBondContact O-N 3.41Å
247K91.1Very high94.8Very high112 Ų11244.6 Ų44.649%0.48725%0.249SC..Hα-helixtrans-65-37.1175.9-177.6178.3175.8-175.90111.7V243 T244 N245V243-K247 HydrophobicContact CG2-CD 4.04Å; T244-K247 WeakPolarHBondContact O-CB 3.37Å; T244-K247 PolarHBondContact O-N 3.01Å; T244-K247 WeakPolarHBondContact OG1-CB 3.43Å; T244-K247 PolarHBondContact OG1-N 3.03Å; N245-K247 PolarHBondContact O-N 2.89Å
248M92.4Very high94.8Very high10 Ų1040 Ų405%0.04923%0.227CC..Hα-helixtrans-67.1-44.1173.3-60.2-48.9-154.700111.3D157 L158 D161 Y235 K239 V243 T244 N245 C246 R250 N251D157-M248 HydrophobicContact CB-CB 3.95Å; D157-M248 VanDerWaalsContact OD2-CB 3.27Å; D157-M248 WeakPolarHBondContact OD2-CB 3.11Å; L158-M248 HydrophobicContact CD1-CE 4.08Å; D161-M248 HydrophobicContact CB-CE 4.31Å; D161-M248 HydrophobicContact CB-SD 4.41Å; Y235-M248 HydrophobicContact CD2-CG 4.01Å; Y235-M248 HydrophobicContact CE2-CG 4.17Å; K239-M248 HydrophobicContact CD-CE 4.24Å; K239-M248 HydrophobicContact CG-CE 4.23Å; V243-M248 HydrophobicContact CB-CE 4.35Å; V243-M248 HydrophobicContact CG1-CE 3.6Å; V243-M248 HydrophobicContact CG1-SD 4.49Å; V243-M248 HydrophobicContact CG2-CE 3.87Å; V243-M248 HydrophobicContact CG2-SD 4.23Å; T244-M248 PolarHBondContact O-N 3.49Å; T244-M248 VanDerWaalsContact O-N 3.16Å; N245-M248 WeakPolarHBondContact O-CA 3.33Å; N245-M248 WeakPolarHBondContact O-CB 3.27Å; N245-M248 PolarHBondContact O-N 3.09Å; C246-M248 VanDerWaalsContact C-N 3.33Å; M248-R250 PolarHBondContact O-N 3.19Å; M248-N251 WeakPolarHBondContact O-CB 3.46Å; M248-N251 PolarHBondContact O-N 3.5Å
249L93.9Very high94.8Very high1 Ų137.7 Ų37.71%0.00521%0.214CC..Hα-helixtrans-64.2-24.1178.4-68.1178.4000114.2Y156 D157 L169 W179 C183 N245 C246 N251 V252 W255Y156-L249 HydrophobicContact CE2-CD2 3.78Å; Y156-L249 VanDerWaalsContact OH-CD2 3.29Å; Y156-L249 WeakPolarHBondContact OH-CD2 3.46Å; D157-L249 HydrophobicContact CB-CD2 4.39Å; L169-L249 HydrophobicContact CD1-CD2 4.16Å; W179-L249 HydrophobicContact CB-CD1 4.24Å; W179-L249 HydrophobicContact CD2-CD1 4.25Å; W179-L249 HydrophobicContact CG-CD1 3.94Å; C183-L249 HydrophobicContact CB-CB 3.62Å; C183-L249 HydrophobicContact CB-CD1 4.11Å; N245-L249 WeakPolarHBondContact O-CG 3.38Å; N245-L249 PolarHBondContact O-N 3.1Å; N245-L249 WeakPolarHBondContact OD1-CD1 3.26Å; C246-L249 PolarHBondContact O-N 2.82Å; L249-N251 PolarHBondContact O-N 3.17Å; L249-V252 HydrophobicContact CD2-CG2 4.03Å; L249-V252 WeakPolarHBondContact O-CB 3.35Å; L249-V252 VanDerWaalsContact O-CG2 3.29Å; L249-V252 WeakPolarHBondContact O-CG2 3.46Å; L249-V252 PolarHBondContact O-N 3.16Å; L249-W255 HydrophobicContact CB-CH2 4.38Å; L249-W255 HydrophobicContact CD2-CH2 4.33Å
250R91.4Very high94.9Very high96 Ų9635.5 Ų35.536%0.36220%0.204SC..THydrogen-bonded Turntrans-60.8-21.1170.2-70.2173.2-175.1-160.20113C183 C246 M248 R476C183-R250 WeakPolarHBondContact O-CG 3.25Å; C246-R250 WeakPolarHBondContact O-CG 3.45Å; C246-R250 PolarHBondContact O-N 3.41Å; M248-R250 PolarHBondContact O-N 3.19Å; R250-R476 PolarHBondContact O-NH1 3.14Å
251N90.3Very high94.9Very high85 Ų8535.7 Ų35.746%0.45518%0.184SC..THydrogen-bonded Turntrans-95.54-179.2-61.7-25.6000113.2M248 L249 D253 R476M248-N251 WeakPolarHBondContact O-CB 3.46Å; M248-N251 PolarHBondContact O-N 3.5Å; L249-N251 PolarHBondContact O-N 3.17Å; N251-D253 PolarHBondContact O-N 3.44Å; N251-R476 PolarHBondContact OD1-NH1 3.04Å; N251-R476 VanDerWaalsContact OD1-NH1 3.09Å
252V96.9Very high94.9Very high7 Ų732 Ų324%0.04216%0.161CC..  trans-61.1124.4171.21730000109.4L167 L169 L249 I254 W255L167-V252 HydrophobicContact CD2-CG2 3.63Å; L167-V252 HydrophobicContact CG-CG2 4.2Å; L169-V252 HydrophobicContact CB-CG1 4.39Å; L169-V252 HydrophobicContact CD1-CB 4.41Å; L169-V252 HydrophobicContact CD1-CG1 3.97Å; L169-V252 HydrophobicContact CD1-CG2 3.55Å; L169-V252 HydrophobicContact CG-CG1 3.77Å; L169-V252 HydrophobicContact CG-CG2 3.93Å; L249-V252 HydrophobicContact CD2-CG2 4.03Å; L249-V252 WeakPolarHBondContact O-CB 3.35Å; L249-V252 VanDerWaalsContact O-CG2 3.29Å; L249-V252 WeakPolarHBondContact O-CG2 3.46Å; L249-V252 PolarHBondContact O-N 3.16Å; V252-I254 WeakPolarHBondContact CG1-O 3.33Å; V252-W255 HydrophobicContact CB-CZ2 3.8Å; V252-W255 HydrophobicContact CG1-CD2 3.95Å; V252-W255 HydrophobicContact CG1-CG 4.03Å; V252-W255 HydrophobicContact CG1-CZ2 4.09Å; V252-W255 HydrophobicContact CG2-CH2 4.33Å; V252-W255 HydrophobicContact CG2-CZ2 3.82Å
253D98Very high95Very high19 Ų1926.3 Ų26.310%0.10212%0.124CC..SBendtrans-76.5-46.1-176.7-67.5-77.1000111.6P166 L167 N251 N272 T466 G471 A472P166-D253 WeakPolarHBondContact CA-OD2 3.36Å; P166-D253 VanDerWaalsContact CB-OD2 3.29Å; P166-D253 WeakPolarHBondContact CB-OD2 3.16Å; L167-D253 PolarHBondContact N-OD2 3.08Å; L167-D253 WeakPolarHBondContact O-CB 3.39Å; L167-D253 PolarHBondContact O-N 3.02Å; N251-D253 PolarHBondContact O-N 3.44Å; D253-N272 WeakPolarHBondContact O-CB 3.46Å; D253-T466 HydrophobicContact CB-CG2 3.89Å; D253-G471 WeakPolarHBondContact OD1-CA 3.42Å; D253-A472 HydrophobicContact CB-CB 3.88Å; D253-A472 PolarHBondContact OD1-N 3.21Å
254I98.5Very high95Very high0 Ų026.3 Ų26.30%012%0.124CC..EExtended strand (participates in β ladder)trans-136.6135.5178.4-62.3-67.3000110.9L167 V168 L169 V252 L256 N272 K274 W462 T466 A472 L475L167-I254 PolarHBondContact O-N 3.27Å; V168-I254 WeakPolarHBondContact CA-O 3.17Å; V168-I254 HydrophobicContact CG1-CB 4.15Å; V168-I254 HydrophobicContact CG1-CG2 4.29Å; V168-I254 HydrophobicContact CG2-CB 4.22Å; L169-I254 PolarHBondContact N-O 3.46Å; V252-I254 WeakPolarHBondContact CG1-O 3.33Å; I254-L256 HydrophobicContact CG2-CD2 3.69Å; I254-L256 HydrophobicContact CG2-CG 4.08Å; I254-N272 WeakPolarHBondContact CA-O 3.49Å; I254-N272 HydrophobicContact CD1-CB 4.29Å; I254-K274 HydrophobicContact CG2-CG 4.11Å; I254-W462 HydrophobicContact CD1-CD2 4.41Å; I254-W462 HydrophobicContact CD1-CE3 3.64Å; I254-W462 HydrophobicContact CD1-CZ3 4.1Å; I254-W462 HydrophobicContact CG1-CE3 4.28Å; I254-W462 HydrophobicContact CG2-CB 4.11Å; I254-T466 WeakPolarHBondContact CG1-OG1 3.28Å; I254-A472 HydrophobicContact CD1-CB 4.11Å; I254-A472 HydrophobicContact CG1-CB 4.32Å; I254-L475 HydrophobicContact CD1-CD1 3.91Å
255W98.3Very high95.2Very high2 Ų224.1 Ų24.11%0.00811%0.109CC..EExtended strand (participates in β ladder)trans-104.3100.8170.8-60.377.8000109.4L169 L171 L249 V252 M257 N272 F273 K274L169-W255 HydrophobicContact CB-CE3 4.48Å; L169-W255 HydrophobicContact CD1-CD2 4.37Å; L169-W255 HydrophobicContact CD1-CE3 3.86Å; L169-W255 HydrophobicContact CD1-CH2 3.82Å; L169-W255 HydrophobicContact CD1-CZ2 4.34Å; L169-W255 HydrophobicContact CD1-CZ3 3.56Å; L171-W255 HydrophobicContact CD2-CE3 3.91Å; L171-W255 HydrophobicContact CD2-CZ3 3.82Å; L249-W255 HydrophobicContact CB-CH2 4.38Å; L249-W255 HydrophobicContact CD2-CH2 4.33Å; V252-W255 HydrophobicContact CB-CZ2 3.8Å; V252-W255 HydrophobicContact CG1-CD2 3.95Å; V252-W255 HydrophobicContact CG1-CG 4.03Å; V252-W255 HydrophobicContact CG1-CZ2 4.09Å; V252-W255 HydrophobicContact CG2-CH2 4.33Å; V252-W255 HydrophobicContact CG2-CZ2 3.82Å; W255-M257 HydrophobicContact CB-SD 4.3Å; W255-M257 PolarHBondContact O-N 2.66Å; W255-N272 PolarHBondContact N-O 2.93Å; W255-F273 HydrophobicContact CB-CB 4.47Å; W255-F273 HydrophobicContact CB-CD1 3.49Å; W255-F273 VanDerWaalsContact CB-CD1 3.49Å; W255-F273 HydrophobicContact CB-CD2 4.16Å; W255-F273 HydrophobicContact CB-CE1 3.62Å; W255-F273 HydrophobicContact CB-CE2 4.29Å; W255-F273 HydrophobicContact CB-CG 3.79Å; W255-F273 HydrophobicContact CB-CZ 4.04Å; W255-F273 AromaticContact CD1-CD2 3.81Å; W255-F273 AromaticContact CD1-CE2 3.41Å; W255-F273 VanDerWaalsContact CD1-CE2 3.41Å; W255-F273 AromaticContact CD1-CZ 3.55Å; W255-F273 AromaticContact CD2-CE1 3.73Å; W255-F273 HydrophobicContact CD2-CE1 3.73Å; W255-F273 HydrophobicContact CD2-CE2 4.26Å; W255-F273 AromaticContact CD2-CZ 3.58Å; W255-F273 HydrophobicContact CD2-CZ 3.58Å; W255-F273 AromaticContact CE2-CZ 3.78Å; W255-F273 HydrophobicContact CE3-CE1 4.08Å; W255-F273 HydrophobicContact CE3-CZ 4.24Å; W255-F273 AromaticContact CG-CD1 3.89Å; W255-F273 HydrophobicContact CG-CD1 3.89Å; W255-F273 HydrophobicContact CG-CD2 4.08Å; W255-F273 AromaticContact CG-CE1 3.52Å; W255-F273 HydrophobicContact CG-CE1 3.52Å; W255-F273 AromaticContact CG-CE2 3.76Å; W255-F273 HydrophobicContact CG-CE2 3.76Å; W255-F273 HydrophobicContact CG-CG 4.16Å; W255-F273 AromaticContact CG-CZ 3.46Å; W255-F273 HydrophobicContact CG-CZ 3.46Å; W255-F273 VanDerWaalsContact CG-CZ 3.46Å; W255-F273 AromaticContact NE1-CE2 3.76Å; W255-F273 AromaticContact NE1-CZ 3.74Å; W255-F273 CarbonylContact O-C 3.52Å; W255-F273 WeakPolarHBondContact O-CA 3.48Å; W255-K274 PolarHBondContact O-N 3.1Å
256L98.4Very high95.3Very high1 Ų127.9 Ų27.91%0.00513%0.134CC..EExtended strand (participates in β ladder)trans-79.690.9169.6-57.7-178.7000109.2F148 V168 L169 S170 L171 I254 R258 K274 V276 A459 W462 I463F148-L256 HydrophobicContact CE2-CD1 4Å; V168-L256 HydrophobicContact CG1-CD1 3.78Å; V168-L256 HydrophobicContact CG1-CG 3.83Å; L169-L256 WeakPolarHBondContact O-CA 3.28Å; L169-L256 WeakPolarHBondContact O-CB 3.48Å; L169-L256 PolarHBondContact O-N 2.78Å; S170-L256 CarbonylContact C-O 3.6Å; S170-L256 WeakPolarHBondContact CA-O 3.16Å; L171-L256 PolarHBondContact N-O 3.41Å; I254-L256 HydrophobicContact CG2-CD2 3.69Å; I254-L256 HydrophobicContact CG2-CG 4.08Å; L256-R258 PolarHBondContact O-N 3.08Å; L256-K274 CarbonylContact C-O 3.55Å; L256-K274 WeakPolarHBondContact CA-O 3.49Å; L256-K274 HydrophobicContact CD2-CB 3.9Å; L256-K274 HydrophobicContact CD2-CG 4.46Å; L256-V276 HydrophobicContact CB-CG2 3.9Å; L256-V276 HydrophobicContact CD2-CG1 4.31Å; L256-A459 HydrophobicContact CD1-CB 3.89Å; L256-W462 HydrophobicContact CD2-CB 3.98Å; L256-W462 HydrophobicContact CD2-CG 4.49Å; L256-I463 HydrophobicContact CD1-CD1 4.23Å; L256-I463 HydrophobicContact CD1-CG1 4.19Å
257M97.6Very high95.4Very high0 Ų027.8 Ų27.80%013%0.13CC..EExtended strand (participates in β ladder)trans-70.6121.1175.6-60.1-52.9-58.500110.1L171 E180 W255 T259 F273 K274 F275 V276L171-M257 HydrophobicContact CB-CE 4.48Å; L171-M257 HydrophobicContact CB-SD 4.24Å; L171-M257 HydrophobicContact CD2-CE 4.15Å; L171-M257 HydrophobicContact CD2-SD 4.23Å; L171-M257 HydrophobicContact CG-CE 4.21Å; L171-M257 HydrophobicContact CG-SD 4.46Å; L171-M257 CarbonylContact O-C 3.54Å; L171-M257 VanDerWaalsContact O-CA 3.24Å; L171-M257 WeakPolarHBondContact O-CA 3.33Å; E180-M257 HydrophobicContact CG-CE 4.11Å; E180-M257 HydrophobicContact CG-SD 4.4Å; W255-M257 HydrophobicContact CB-SD 4.3Å; W255-M257 PolarHBondContact O-N 2.66Å; M257-T259 PolarHBondContact O-N 2.85Å; M257-F273 HydrophobicContact CG-CD1 3.83Å; M257-F273 HydrophobicContact SD-CD1 3.82Å; M257-F273 HydrophobicContact SD-CE1 4.04Å; M257-K274 PolarHBondContact N-O 3.39Å; M257-F275 HydrophobicContact CB-CD1 3.73Å; M257-F275 HydrophobicContact CB-CE1 3.78Å; M257-F275 HydrophobicContact CB-CG 4.14Å; M257-F275 HydrophobicContact CB-CZ 4.21Å; M257-F275 HydrophobicContact CG-CD1 4.36Å; M257-F275 HydrophobicContact CG-CE1 3.97Å; M257-F275 HydrophobicContact CG-CE2 4.29Å; M257-F275 HydrophobicContact CG-CZ 3.93Å; M257-F275 CarbonylContact O-C 3.55Å; M257-F275 WeakPolarHBondContact O-CA 3.47Å; M257-V276 WeakPolarHBondContact O-CG2 3.45Å; M257-V276 PolarHBondContact O-N 3.38Å
258R96.4Very high95.6Very high16 Ų1624.5 Ų24.56%0.0612%0.12CC..SBendtrans-77.429.7178.1-62.8-166.3-66.5-89.66.3113.5H33 N36 D150 S170 L171 R172 L256 Y380H33-R258 PolarHBondContact ND1-NH2 3.04Å; N36-R258 WeakPolarHBondContact OD1-CD 3.24Å; D150-R258 IonicContact OD2-CZ 3.09Å; D150-R258 IonicContact OD2-NH1 3.33Å; D150-R258 PolarHBondContact OD2-NH1 3.46Å; D150-R258 IonicContact OD2-NH2 2.64Å; D150-R258 PolarHBondContact OD2-NH2 3.29Å; S170-R258 PolarHBondContact O-NH1 2.91Å; S170-R258 WeakPolarHBondContact OG-CD 3.4Å; S170-R258 WeakPolarHBondContact OG-CG 3.42Å; S170-R258 PolarHBondContact OG-NH1 2.8Å; L171-R258 PolarHBondContact O-N 3.37Å; R172-R258 HydrophobicContact CB-CB 4.29Å; L256-R258 PolarHBondContact O-N 3.08Å; R258-Y380 WeakPolarHBondContact O-CE2 3.48Å
259T95.8Very high95.7Very high0 Ų028 Ų280%014%0.139CC..  trans-123.4166.3172.262.90000112.7R172 M257 F263 D264 F275 G277 Y380R172-T259 VanDerWaalsContact CD-CG2 3.49Å; M257-T259 PolarHBondContact O-N 2.85Å; T259-F263 HydrophobicContact CG2-CD1 4.31Å; T259-F263 HydrophobicContact CG2-CE1 4.39Å; T259-D264 VanDerWaalsContact CB-OD2 3.3Å; T259-D264 WeakPolarHBondContact CB-OD2 3.42Å; T259-D264 PolarHBondContact OG1-OD2 3.29Å; T259-F275 CarbonylContact O-C 3.52Å; T259-F275 WeakPolarHBondContact O-CA 3.46Å; T259-F275 VanDerWaalsContact O-CB 3.3Å; T259-F275 WeakPolarHBondContact O-CB 3.37Å; T259-G277 PolarHBondContact O-N 2.85Å; T259-Y380 VanDerWaalsContact C-OH 3.31Å; T259-Y380 WeakPolarHBondContact CA-OH 3.3Å
260F96.4Very high95.8Very high33 Ų3329 Ų2915%0.14514%0.144CC..  trans-157.2167.6173.2-160-101.6000109.6D262 F263 D264 F275 Y380 R451F260-D262 VanDerWaalsContact C-N 3.29Å; F260-D262 VanDerWaalsContact C-OD1 3.26Å; F260-D262 WeakPolarHBondContact CB-OD1 3.26Å; F260-D262 PolarHBondContact O-N 3.44Å; F260-F263 PolarHBondContact O-N 3.21Å; F260-D264 WeakPolarHBondContact O-CB 3.18Å; F260-D264 PolarHBondContact O-N 2.95Å; F260-F275 HydrophobicContact CD2-CB 3.91Å; F260-F275 WeakPolarHBondContact CD2-O 3.46Å; F260-Y380 PolarHBondContact N-OH 2.95Å; F260-R451 VanDerWaalsContact CB-NH2 3.27Å; F260-R451 HydrophobicContact CE1-CG 4.13Å; F260-R451 VanDerWaalsContact CE1-NE 3.27Å; F260-R451 VanDerWaalsContact CG-NH1 3.34Å; F260-R451 HydrophobicContact CZ-CG 4.03Å
261W95.1Very high96.1Very high71 Ų7127.5 Ų27.527%0.26915%0.147SC..THydrogen-bonded Turntrans-73.3-15.1-165.5-45.2117.5000115.6F265 R267 L269 F275 K408W261-F265 VanDerWaalsContact CZ3-O 3.26Å; W261-F265 WeakPolarHBondContact CZ3-O 3.49Å; W261-R267 HydrophobicContact CH2-CG 4.1Å; W261-R267 HydrophobicContact CZ3-CG 4.16Å; W261-L269 HydrophobicContact CH2-CD1 4.33Å; W261-L269 HydrophobicContact CH2-CD2 3.6Å; W261-L269 HydrophobicContact CH2-CG 4.32Å; W261-L269 HydrophobicContact CZ2-CD1 3.67Å; W261-L269 HydrophobicContact CZ2-CD2 3.8Å; W261-L269 HydrophobicContact CZ2-CG 4.16Å; W261-F275 HydrophobicContact CH2-CD1 4.38Å; W261-F275 HydrophobicContact CH2-CE1 4.14Å; W261-F275 HydrophobicContact CH2-CZ 4.32Å; W261-F275 HydrophobicContact CZ2-CD1 4.4Å; W261-F275 HydrophobicContact CZ2-CD2 4.47Å; W261-F275 HydrophobicContact CZ2-CG 4.36Å; W261-K408 PolarHBondContact O-NZ 3.29Å
262D95.9Very high96.4Very high0 Ų023.7 Ų23.70%013%0.126CC..THydrogen-bonded Turntrans-63.4-31.9167.350.30.6000111.7F260 I383 K408 L444 I447 H448 R451F260-D262 VanDerWaalsContact C-N 3.29Å; F260-D262 VanDerWaalsContact C-OD1 3.26Å; F260-D262 WeakPolarHBondContact CB-OD1 3.26Å; F260-D262 PolarHBondContact O-N 3.44Å; D262-I383 HydrophobicContact CB-CG2 4.27Å; D262-K408 WeakPolarHBondContact O-CD 3.17Å; D262-K408 WeakPolarHBondContact O-CE 3.39Å; D262-K408 PolarHBondContact O-NZ 3.44Å; D262-L444 HydrophobicContact CB-CB 4.44Å; D262-L444 WeakPolarHBondContact O-CD2 3.42Å; D262-I447 HydrophobicContact CB-CB 4.31Å; D262-I447 HydrophobicContact CB-CG2 4.04Å; D262-H448 WeakPolarHBondContact OD2-CA 3.37Å; D262-H448 WeakPolarHBondContact OD2-CB 3.24Å; D262-H448 IonicContact OD2-CE1 3.7Å; D262-H448 IonicContact OD2-CG 2.79Å; D262-H448 VanDerWaalsContact OD2-CG 3.27Å; D262-H448 IonicContact OD2-ND1 2.76Å; D262-H448 PolarHBondContact OD2-ND1 3.48Å; D262-R451 IonicContact OD1-NH2 3.85Å; D262-R451 IonicContact OD2-NH2 3.66Å; D262-R451 PolarHBondContact OD2-NH2 3.4Å
263F96.9Very high96.5Very high0 Ų023.6 Ų23.60%013%0.125CC..THydrogen-bonded Turntrans-108.6-44.6179.1170.7-126000113.9R172 T259 F260 T376 I379 Y380 I383 N401 H404 M405 K408R172-F263 VanDerWaalsContact NH2-CE1 3.32Å; T259-F263 HydrophobicContact CG2-CD1 4.31Å; T259-F263 HydrophobicContact CG2-CE1 4.39Å; F260-F263 PolarHBondContact O-N 3.21Å; F263-T376 HydrophobicContact CE1-CG2 4.3Å; F263-I379 HydrophobicContact CD2-CG2 3.7Å; F263-I379 HydrophobicContact CE2-CD1 4Å; F263-I379 HydrophobicContact CE2-CG2 3.95Å; F263-I379 HydrophobicContact CG-CG2 4.26Å; F263-I379 HydrophobicContact CZ-CD1 4.34Å; F263-Y380 HydrophobicContact CB-CE1 4.02Å; F263-Y380 WeakPolarHBondContact CB-OH 3.25Å; F263-Y380 AromaticContact CD1-CE2 3.97Å; F263-Y380 HydrophobicContact CD1-CE2 3.97Å; F263-Y380 AromaticContact CD1-CZ 3.9Å; F263-Y380 WeakPolarHBondContact CD1-OH 3.48Å; F263-I383 HydrophobicContact CB-CD1 3.9Å; F263-N401 HydrophobicContact CE2-CB 4.17Å; F263-N401 HydrophobicContact CZ-CB 3.79Å; F263-N401 WeakPolarHBondContact CZ-OD1 3.38Å; F263-H404 HydrophobicContact CD2-CB 4.38Å; F263-H404 HydrophobicContact CE2-CB 3.92Å; F263-M405 HydrophobicContact CD2-CG 4.37Å; F263-M405 HydrophobicContact CD2-SD 3.66Å; F263-M405 HydrophobicContact CE2-CG 4.29Å; F263-M405 HydrophobicContact CE2-SD 4.17Å; F263-K408 WeakPolarHBondContact O-CE 3.21Å
264D95.4Very high96.5Very high12 Ų1224.4 Ų24.46%0.06413%0.128CC..SBendtrans-87.9175.1-175.8-147.3-23.7000111.8T259 F260 H404 K408T259-D264 VanDerWaalsContact CB-OD2 3.3Å; T259-D264 WeakPolarHBondContact CB-OD2 3.42Å; T259-D264 PolarHBondContact OG1-OD2 3.29Å; F260-D264 WeakPolarHBondContact O-CB 3.18Å; F260-D264 PolarHBondContact O-N 2.95Å; D264-H404 IonicContact OD1-NE2 3.6Å; D264-K408 PolarHBondContact O-NZ 3.39Å
265F95.8Very high96.4Very high14 Ų1424.9 Ų24.96%0.06113%0.13CC..  trans-95.9142.3172.7-60.6-65.6000111.9P194 T201 D202 W261 R267 H404 A407P194-F265 HydrophobicContact CG-CD2 4.06Å; T201-F265 HydrophobicContact CG2-CE2 4.41Å; T201-F265 HydrophobicContact CG2-CZ 3.96Å; D202-F265 HydrophobicContact CB-CB 3.77Å; D202-F265 HydrophobicContact CB-CD1 3.98Å; D202-F265 HydrophobicContact CB-CD2 4.37Å; D202-F265 HydrophobicContact CB-CG 3.79Å; D202-F265 VanDerWaalsContact OD1-CD1 3.25Å; D202-F265 WeakPolarHBondContact OD1-CD1 3.48Å; D202-F265 WeakPolarHBondContact OD1-CE1 3.24Å; W261-F265 VanDerWaalsContact CZ3-O 3.26Å; W261-F265 WeakPolarHBondContact CZ3-O 3.49Å; F265-R267 PolarHBondContact O-N 3.14Å; F265-H404 AromaticContact CD2-CD2 3.48Å; F265-H404 VanDerWaalsContact CD2-CD2 3.48Å; F265-H404 WeakPolarHBondContact CD2-CD2 3.4Å; F265-H404 AromaticContact CD2-NE2 3.48Å; F265-H404 WeakPolarHBondContact CD2-NE2 3.28Å; F265-H404 AromaticContact CE2-CD2 3.21Å; F265-H404 WeakPolarHBondContact CE2-CD2 3.28Å; F265-H404 AromaticContact CE2-CE1 3.97Å; F265-H404 AromaticContact CE2-CG 3.75Å; F265-H404 AromaticContact CE2-NE2 3.38Å; F265-H404 WeakPolarHBondContact CE2-NE2 3.31Å; F265-H404 AromaticContact CZ-CD2 3.94Å; F265-A407 HydrophobicContact CE1-CB 4.42Å; F265-A407 HydrophobicContact CZ-CB 4.1Å
266P94.4Very high96.3Very high82 Ų8224.9 Ų24.953%0.53213%0.13SC..  trans-56.1135.9177.9-25.134.8000113.4
267R94.8Very high96.3Very high22 Ų2224.8 Ų24.88%0.08313%0.13CC..  trans-151.6162.7179.467.7-172.8-171.8170.64.7112.6H177 V193 W261 F265 L269H177-R267 PolarHBondContact CE1-NH1 2.99Å; H177-R267 PolarHBondContact ND1-NH1 2.94Å; H177-R267 PolarHBondContact NE2-NH1 2.85Å; H177-R267 VanDerWaalsContact NE2-NH1 3.15Å; V193-R267 HydrophobicContact CG1-CB 4.43Å; V193-R267 HydrophobicContact CG2-CB 3.83Å; W261-R267 HydrophobicContact CH2-CG 4.1Å; W261-R267 HydrophobicContact CZ3-CG 4.16Å; F265-R267 PolarHBondContact O-N 3.14Å; R267-L269 HydrophobicContact CG-CD2 4.44Å
268P95.6Very high96.2Very high44 Ų4425 Ų2529%0.28613%0.132SC..  trans-58.1144.9176.2-23.434.7000112.3P187 P189 F192P187-P268 HydrophobicContact CB-CB 3.94Å; P187-P268 HydrophobicContact CB-CG 4.32Å; P187-P268 HydrophobicContact CG-CB 4.21Å; P189-P268 HydrophobicContact CG-CG 4.31Å; F192-P268 HydrophobicContact CZ-CG 4.23Å
269L94.9Very high96.1Very high83 Ų8324.4 Ų24.444%0.43513%0.13SC..  trans-124.8151.8-176-55.6-175.7000112.1W261 R267 F275W261-L269 HydrophobicContact CH2-CD1 4.33Å; W261-L269 HydrophobicContact CH2-CD2 3.6Å; W261-L269 HydrophobicContact CH2-CG 4.32Å; W261-L269 HydrophobicContact CZ2-CD1 3.67Å; W261-L269 HydrophobicContact CZ2-CD2 3.8Å; W261-L269 HydrophobicContact CZ2-CG 4.16Å; R267-L269 HydrophobicContact CG-CD2 4.44Å; L269-F275 HydrophobicContact CD1-CD2 4.33Å; L269-F275 HydrophobicContact CD1-CE2 4.17Å; L269-F275 HydrophobicContact CD2-CD2 4.09Å; L269-F275 HydrophobicContact CD2-CE1 4.34Å; L269-F275 HydrophobicContact CD2-CE2 3.2Å; L269-F275 HydrophobicContact CD2-CZ 3.34Å; L269-F275 HydrophobicContact CG-CE2 4.19Å
270L96.1Very high96Very high21 Ų2125 Ų2511%0.1113%0.133CC..  trans-107.1153169.1-64.4-170.9000111.6Q185 L186 P187 N272 F273 V477Q185-L270 HydrophobicContact CB-CD1 4.48Å; Q185-L270 WeakPolarHBondContact O-CD1 3.48Å; L186-L270 HydrophobicContact CD1-CB 4.32Å; L186-L270 HydrophobicContact CD1-CG 4Å; P187-L270 HydrophobicContact CG-CD2 4.5Å; L270-N272 WeakPolarHBondContact CB-OD1 3.43Å; L270-N272 PolarHBondContact O-N 2.96Å; L270-N272 VanDerWaalsContact O-N 3.14Å; L270-F273 HydrophobicContact CB-CD2 3.84Å; L270-F273 HydrophobicContact CB-CE2 4.47Å; L270-F273 HydrophobicContact CD1-CD2 4.37Å; L270-F273 HydrophobicContact CD1-CE2 4.2Å; L270-F273 HydrophobicContact CG-CD2 4.5Å; L270-F273 PolarHBondContact O-N 3.27Å; L270-V477 HydrophobicContact CD1-CG1 4.03Å; L270-V477 HydrophobicContact CD1-CG2 3.75Å; L270-V477 HydrophobicContact CD2-CG1 3.53Å; L270-V477 HydrophobicContact CG-CG1 4.24Å
271P96.8Very high95.9Very high65 Ų6524 Ų2442%0.42213%0.13SC..THydrogen-bonded Turntrans-61.1-23.8-177-24.835.1000115K274 L475P271-K274 WeakPolarHBondContact O-CE 3.29Å; P271-K274 PolarHBondContact O-NZ 3.3Å; P271-L475 HydrophobicContact CB-CB 4.19Å; P271-L475 HydrophobicContact CB-CD2 4.02Å
272N97.3Very high95.9Very high5 Ų525 Ų253%0.02714%0.136CC..THydrogen-bonded Turntrans-93.2-0.6177.364.9-36000114.2D253 I254 W255 L270 L475D253-N272 WeakPolarHBondContact O-CB 3.46Å; I254-N272 WeakPolarHBondContact CA-O 3.49Å; I254-N272 HydrophobicContact CD1-CB 4.29Å; W255-N272 PolarHBondContact N-O 2.93Å; L270-N272 WeakPolarHBondContact CB-OD1 3.43Å; L270-N272 PolarHBondContact O-N 2.96Å; L270-N272 VanDerWaalsContact O-N 3.14Å; N272-L475 HydrophobicContact CB-CB 3.88Å
273F97.8Very high95.9Very high6 Ų629.3 Ų29.33%0.02616%0.164CC..EExtended strand (participates in β ladder)trans-99121.7173-77.6-109.2000110E180 L186 W255 M257 L270 F275E180-F273 HydrophobicContact CB-CE1 4.11Å; E180-F273 HydrophobicContact CB-CZ 4.48Å; E180-F273 HydrophobicContact CG-CE1 4.09Å; L186-F273 HydrophobicContact CB-CE1 4.04Å; L186-F273 HydrophobicContact CB-CE2 4.17Å; L186-F273 HydrophobicContact CB-CZ 3.84Å; L186-F273 HydrophobicContact CD1-CB 4.42Å; L186-F273 HydrophobicContact CD1-CD1 4.19Å; L186-F273 HydrophobicContact CD1-CD2 4.24Å; L186-F273 HydrophobicContact CD1-CG 4.03Å; L186-F273 HydrophobicContact CD2-CD1 3.85Å; L186-F273 HydrophobicContact CD2-CE1 3.86Å; L186-F273 HydrophobicContact CG-CD1 4.42Å; L186-F273 HydrophobicContact CG-CE1 4.37Å; W255-F273 HydrophobicContact CB-CB 4.47Å; W255-F273 HydrophobicContact CB-CD1 3.49Å; W255-F273 VanDerWaalsContact CB-CD1 3.49Å; W255-F273 HydrophobicContact CB-CD2 4.16Å; W255-F273 HydrophobicContact CB-CE1 3.62Å; W255-F273 HydrophobicContact CB-CE2 4.29Å; W255-F273 HydrophobicContact CB-CG 3.79Å; W255-F273 HydrophobicContact CB-CZ 4.04Å; W255-F273 AromaticContact CD1-CD2 3.81Å; W255-F273 AromaticContact CD1-CE2 3.41Å; W255-F273 VanDerWaalsContact CD1-CE2 3.41Å; W255-F273 AromaticContact CD1-CZ 3.55Å; W255-F273 AromaticContact CD2-CE1 3.73Å; W255-F273 HydrophobicContact CD2-CE1 3.73Å; W255-F273 HydrophobicContact CD2-CE2 4.26Å; W255-F273 AromaticContact CD2-CZ 3.58Å; W255-F273 HydrophobicContact CD2-CZ 3.58Å; W255-F273 AromaticContact CE2-CZ 3.78Å; W255-F273 HydrophobicContact CE3-CE1 4.08Å; W255-F273 HydrophobicContact CE3-CZ 4.24Å; W255-F273 AromaticContact CG-CD1 3.89Å; W255-F273 HydrophobicContact CG-CD1 3.89Å; W255-F273 HydrophobicContact CG-CD2 4.08Å; W255-F273 AromaticContact CG-CE1 3.52Å; W255-F273 HydrophobicContact CG-CE1 3.52Å; W255-F273 AromaticContact CG-CE2 3.76Å; W255-F273 HydrophobicContact CG-CE2 3.76Å; W255-F273 HydrophobicContact CG-CG 4.16Å; W255-F273 AromaticContact CG-CZ 3.46Å; W255-F273 HydrophobicContact CG-CZ 3.46Å; W255-F273 VanDerWaalsContact CG-CZ 3.46Å; W255-F273 AromaticContact NE1-CE2 3.76Å; W255-F273 AromaticContact NE1-CZ 3.74Å; W255-F273 CarbonylContact O-C 3.52Å; W255-F273 WeakPolarHBondContact O-CA 3.48Å; M257-F273 HydrophobicContact CG-CD1 3.83Å; M257-F273 HydrophobicContact SD-CD1 3.82Å; M257-F273 HydrophobicContact SD-CE1 4.04Å; L270-F273 HydrophobicContact CB-CD2 3.84Å; L270-F273 HydrophobicContact CB-CE2 4.47Å; L270-F273 HydrophobicContact CD1-CD2 4.37Å; L270-F273 HydrophobicContact CD1-CE2 4.2Å; L270-F273 HydrophobicContact CG-CD2 4.5Å; L270-F273 PolarHBondContact O-N 3.27Å; F273-F275 HydrophobicContact CB-CE2 4.07Å
274K97.6Very high95.9Very high36 Ų3631.4 Ų31.416%0.15718%0.181CC..EExtended strand (participates in β ladder)trans-123.2129.8-175.2-52.6-63.4170.8-177.70110.2I254 W255 L256 M257 P271 W462I254-K274 HydrophobicContact CG2-CG 4.11Å; W255-K274 PolarHBondContact O-N 3.1Å; L256-K274 CarbonylContact C-O 3.55Å; L256-K274 WeakPolarHBondContact CA-O 3.49Å; L256-K274 HydrophobicContact CD2-CB 3.9Å; L256-K274 HydrophobicContact CD2-CG 4.46Å; M257-K274 PolarHBondContact N-O 3.39Å; P271-K274 WeakPolarHBondContact O-CE 3.29Å; P271-K274 PolarHBondContact O-NZ 3.3Å; K274-W462 HydrophobicContact CB-CG 4.48Å; K274-W462 HydrophobicContact CD-CD2 4Å; K274-W462 HydrophobicContact CD-CG 4.39Å; K274-W462 HydrophobicContact CD-CH2 4.41Å; K274-W462 HydrophobicContact CD-CZ2 3.65Å; K274-W462 VanDerWaalsContact CE-CH2 3.42Å; K274-W462 HydrophobicContact CG-CD2 3.8Å; K274-W462 HydrophobicContact CG-CG 3.79Å; K274-W462 HydrophobicContact CG-CZ2 4.4Å
275F96.8Very high96Very high10 Ų1037.3 Ų37.34%0.04421%0.207CC..EExtended strand (participates in β ladder)trans-102.9101.4-167.7-74.2-99.1000109.3M257 T259 F260 W261 L269 F273M257-F275 HydrophobicContact CB-CD1 3.73Å; M257-F275 HydrophobicContact CB-CE1 3.78Å; M257-F275 HydrophobicContact CB-CG 4.14Å; M257-F275 HydrophobicContact CB-CZ 4.21Å; M257-F275 HydrophobicContact CG-CD1 4.36Å; M257-F275 HydrophobicContact CG-CE1 3.97Å; M257-F275 HydrophobicContact CG-CE2 4.29Å; M257-F275 HydrophobicContact CG-CZ 3.93Å; M257-F275 CarbonylContact O-C 3.55Å; M257-F275 WeakPolarHBondContact O-CA 3.47Å; T259-F275 CarbonylContact O-C 3.52Å; T259-F275 WeakPolarHBondContact O-CA 3.46Å; T259-F275 VanDerWaalsContact O-CB 3.3Å; T259-F275 WeakPolarHBondContact O-CB 3.37Å; F260-F275 HydrophobicContact CD2-CB 3.91Å; F260-F275 WeakPolarHBondContact CD2-O 3.46Å; W261-F275 HydrophobicContact CH2-CD1 4.38Å; W261-F275 HydrophobicContact CH2-CE1 4.14Å; W261-F275 HydrophobicContact CH2-CZ 4.32Å; W261-F275 HydrophobicContact CZ2-CD1 4.4Å; W261-F275 HydrophobicContact CZ2-CD2 4.47Å; W261-F275 HydrophobicContact CZ2-CG 4.36Å; L269-F275 HydrophobicContact CD1-CD2 4.33Å; L269-F275 HydrophobicContact CD1-CE2 4.17Å; L269-F275 HydrophobicContact CD2-CD2 4.09Å; L269-F275 HydrophobicContact CD2-CE1 4.34Å; L269-F275 HydrophobicContact CD2-CE2 3.2Å; L269-F275 HydrophobicContact CD2-CZ 3.34Å; L269-F275 HydrophobicContact CG-CE2 4.19Å; F273-F275 HydrophobicContact CB-CE2 4.07Å
276V97.5Very high96.1Very high1 Ų142.9 Ų42.91%0.00624%0.244CC..  trans-112.636.3-171.9-61.50000111.2L256 M257 G278 I279 E458 A459L256-V276 HydrophobicContact CB-CG2 3.9Å; L256-V276 HydrophobicContact CD2-CG1 4.31Å; M257-V276 WeakPolarHBondContact O-CG2 3.45Å; M257-V276 PolarHBondContact O-N 3.38Å; V276-G278 PolarHBondContact O-N 3.42Å; V276-I279 HydrophobicContact CB-CG2 3.55Å; V276-I279 HydrophobicContact CG2-CG2 3.77Å; V276-I279 WeakPolarHBondContact O-CG2 3.19Å; V276-I279 PolarHBondContact O-N 3.38Å; V276-E458 HydrophobicContact CG1-CB 4.18Å; V276-E458 HydrophobicContact CG1-CG 3.99Å; V276-A459 HydrophobicContact CB-CB 4.46Å; V276-A459 HydrophobicContact CG1-CB 4.16Å
277G96.7Very high96.2Very high0 Ų039.8 Ų39.80%022%0.223CC..THydrogen-bonded Turntrans-53.1130.1175.300000112.4T259 R451 P455T259-G277 PolarHBondContact O-N 2.85Å; G277-R451 PolarHBondContact O-NH1 2.8Å; G277-R451 PolarHBondContact O-NH2 2.73Å; G277-P455 WeakPolarHBondContact O-CG 3.38Å
278G95.8Very high96.3Very high5 Ų542.1 Ų42.15%0.05224%0.241CC..THydrogen-bonded Turntrans82.822.3-178.500000116.4V276 H280 C281V276-G278 PolarHBondContact O-N 3.42Å; G278-H280 PolarHBondContact O-N 3.46Å; G278-C281 VanDerWaalsContact O-CB 3.31Å; G278-C281 WeakPolarHBondContact O-CB 3.36Å; G278-C281 PolarHBondContact O-N 3.1Å
279I95.3Very high96.4Very high2 Ų249.3 Ų49.31%0.0127%0.268CS..THydrogen-bonded Turntrans-52.6-27.7177.652172.7000115.8N36 V40 V276 P455 R456 A459N36-I279 WeakPolarHBondContact ND2-CG1 3.16Å; N36-I279 WeakPolarHBondContact OD1-CD1 3.48Å; N36-I279 WeakPolarHBondContact OD1-CG1 3.3Å; V40-I279 HydrophobicContact CG2-CB 4.44Å; V40-I279 HydrophobicContact CG2-CD1 3.9Å; V276-I279 HydrophobicContact CB-CG2 3.55Å; V276-I279 HydrophobicContact CG2-CG2 3.77Å; V276-I279 WeakPolarHBondContact O-CG2 3.19Å; V276-I279 PolarHBondContact O-N 3.38Å; I279-P455 HydrophobicContact CG2-CB 3.88Å; I279-P455 WeakPolarHBondContact CG2-O 3.49Å; I279-R456 PolarHBondContact O-NE 3.3Å; I279-A459 HydrophobicContact CG2-CB 4.3Å
280H93.9Very high96.4Very high13 Ų1353.6 Ų53.66%0.0628%0.283CS..THydrogen-bonded Turntrans-86.4-15.5178.963.1-72.7000113.6N36 P39 G278 N377 E381N36-H280 PolarHBondContact ND2-ND1 3.02Å; P39-H280 HydrophobicContact CG-CB 4.32Å; G278-H280 PolarHBondContact O-N 3.46Å; H280-N377 VanDerWaalsContact CE1-CA 3.47Å; H280-N377 WeakPolarHBondContact CE1-CA 3.25Å; H280-N377 PolarHBondContact CE1-O 2.88Å; H280-N377 WeakPolarHBondContact NE2-CA 3.33Å; H280-N377 PolarHBondContact NE2-O 3.15Å; H280-E381 IonicContact CD2-OE1 3.97Å
281C94.6Very high96.4Very high12 Ų1253.4 Ų53.48%0.08128%0.282CS..  trans-65.3148.6-177.5-62.60000111.3G278 Y380 Y384G278-C281 VanDerWaalsContact O-CB 3.31Å; G278-C281 WeakPolarHBondContact O-CB 3.36Å; G278-C281 PolarHBondContact O-N 3.1Å; C281-Y380 VanDerWaalsContact SG-C 3.52Å; C281-Y384 HydrophobicContact CB-CD2 3.36Å; C281-Y384 HydrophobicContact CB-CE2 3.88Å; C281-Y384 HydrophobicContact CB-CG 3.79Å
282K93.7Very high96.5Very high91 Ų9152.7 Ų52.740%0.39627%0.273SS..  trans-154.7155.3-177.862.2-167.6175.8-170.40110.9N359 Y384K282-N359 VanDerWaalsContact CG-ND2 3.34Å; K282-N359 WeakPolarHBondContact CG-ND2 3.37Å; K282-N359 PolarHBondContact O-ND2 3.06Å; K282-N359 PolarHBondContact O-OD1 3.4Å; K282-Y384 WeakPolarHBondContact O-CE1 3.3Å
283P96.2Very high96.5Very high91 Ų9160.5 Ų60.559%0.59131%0.307SS*.PPolyproline II helixtrans-54.2145.4170.8-24.534.3000111.3Y384P283-Y384 VanDerWaalsContact CD-OH 3.3Å; P283-Y384 WeakPolarHBondContact CD-OH 3.32Å
284A97.1Very high96.5Very high44 Ų4460.8 Ų60.836%0.36431%0.308SS..PPolyproline II helixtrans-66.8135.5178.400000111.2D360A284-D360 WeakPolarHBondContact CA-OD1 3.45Å; A284-D360 HydrophobicContact CB-CB 4.49Å
285K97.1Very high96.5Very high137 Ų13759.1 Ų59.160%0.59630%0.3SS*.PPolyproline II helixtrans-93158.9170.7-64.9-174.9179.3-174.40110.7L287 D360K285-L287 PolarHBondContact O-N 3.47Å; K285-D360 PolarHBondContact N-OD1 3.15Å
286P97.4Very high96.6Very high130 Ų13063 Ų6384%0.84432%0.319SS*.PPolyproline II helixtrans-55.6135.6173.3-25.835.1000112.3
287L97.7Very high96.6Very high17 Ų1766.3 Ų66.39%0.08934%0.342CS..PPolyproline II helixtrans-73.4150.7180-63175.9000111.5K285 K289 I291 E292 V295 P357 D360 L361K285-L287 PolarHBondContact O-N 3.47Å; L287-K289 PolarHBondContact O-N 2.98Å; L287-I291 HydrophobicContact CD1-CG2 4.24Å; L287-E292 HydrophobicContact CB-CB 4.25Å; L287-E292 WeakPolarHBondContact CD1-OE2 3.32Å; L287-V295 HydrophobicContact CD1-CG2 4.06Å; L287-P357 HydrophobicContact CD2-CG 3.85Å; L287-D360 HydrophobicContact CD2-CB 3.67Å; L287-L361 HydrophobicContact CD1-CD2 3.7Å; L287-L361 HydrophobicContact CD2-CD2 4.04Å; L287-L361 HydrophobicContact CD2-CG 4.04Å
288P97.1Very high96.6Very high72 Ų7266.8 Ų66.847%0.46835%0.345SS..PPolyproline II helixtrans-54.5137169.2-25.334.1000111.4K290 I291 E292P288-K290 PolarHBondContact O-N 3.49Å; P288-I291 HydrophobicContact CB-CD1 4.44Å; P288-I291 HydrophobicContact CB-CG1 4.42Å; P288-I291 HydrophobicContact CG-CD1 4.14Å; P288-I291 WeakPolarHBondContact O-CA 3.4Å; P288-I291 WeakPolarHBondContact O-CB 3.48Å; P288-I291 PolarHBondContact O-N 2.86Å; P288-E292 PolarHBondContact O-N 2.8Å
289K96.7Very high96.6Very high195 Ų19568.3 Ų68.385%0.84836%0.361SS*.Hα-helixtrans-47.2-38.9-173.3-66.9-175.2179.3-179.70114.3L287 K293L287-K289 PolarHBondContact O-N 2.98Å; K289-K293 WeakPolarHBondContact O-CB 3.48Å; K289-K293 PolarHBondContact O-N 3Å
290K95.3Very high96.7Very high172 Ų17275.7 Ų75.775%0.74840%0.4SS*.Hα-helixtrans-67.4-39.8179.3-174.8179.5178-177.10112.8P288P288-K290 PolarHBondContact O-N 3.49Å
291I97.2Very high96.9Very high17 Ų1776.5 Ų76.59%0.08741%0.409CS..Hα-helixtrans-71.6-47.6176.9-60.9-176.6000108.7L287 P288 K293 F294 V295 L335 Y353 P357 L361L287-I291 HydrophobicContact CD1-CG2 4.24Å; P288-I291 HydrophobicContact CB-CD1 4.44Å; P288-I291 HydrophobicContact CB-CG1 4.42Å; P288-I291 HydrophobicContact CG-CD1 4.14Å; P288-I291 WeakPolarHBondContact O-CA 3.4Å; P288-I291 WeakPolarHBondContact O-CB 3.48Å; P288-I291 PolarHBondContact O-N 2.86Å; I291-K293 VanDerWaalsContact C-N 3.33Å; I291-K293 PolarHBondContact O-N 2.88Å; I291-F294 WeakPolarHBondContact O-CA 3.41Å; I291-F294 WeakPolarHBondContact O-CB 3.44Å; I291-F294 PolarHBondContact O-N 3.01Å; I291-V295 HydrophobicContact CG2-CG2 4.31Å; I291-V295 WeakPolarHBondContact O-CG2 3.2Å; I291-V295 PolarHBondContact O-N 3.32Å; I291-L335 HydrophobicContact CG2-CD2 3.69Å; I291-Y353 HydrophobicContact CD1-CE1 4.16Å; I291-Y353 HydrophobicContact CG1-CE1 4.02Å; I291-P357 HydrophobicContact CD1-CG 4.13Å; I291-L361 HydrophobicContact CG2-CD2 3.98Å
292E97.8Very high97.1Very high50 Ų5076 Ų7623%0.23441%0.406CS..Hα-helixtrans-53.6-47.7177.8-174.558.4-149.600111.9L287 P288 F294 V295 Q296 H364L287-E292 HydrophobicContact CB-CB 4.25Å; L287-E292 WeakPolarHBondContact CD1-OE2 3.32Å; P288-E292 PolarHBondContact O-N 2.8Å; E292-F294 PolarHBondContact O-N 3.1Å; E292-V295 PolarHBondContact O-N 3.11Å; E292-V295 VanDerWaalsContact O-N 3.08Å; E292-Q296 HydrophobicContact CG-CG 4.37Å; E292-Q296 WeakPolarHBondContact O-CG 3.47Å; E292-Q296 PolarHBondContact O-N 3.28Å; E292-Q296 WeakPolarHBondContact OE1-CG 3.42Å; E292-Q296 PolarHBondContact OE1-NE2 2.87Å; E292-H364 IonicContact OE1-NE2 3.43Å; E292-H364 IonicContact OE2-CD2 2.6Å; E292-H364 IonicContact OE2-NE2 3.25Å
293K97.5Very high97.3Very high170 Ų17071.6 Ų71.674%0.73939%0.387SS*.Hα-helixtrans-57.3-36177.1-175.2175.6-179.7177.60113K289 I291 S297K289-K293 WeakPolarHBondContact O-CB 3.48Å; K289-K293 PolarHBondContact O-N 3Å; I291-K293 VanDerWaalsContact C-N 3.33Å; I291-K293 PolarHBondContact O-N 2.88Å; K293-S297 PolarHBondContact O-N 3.47Å
294F97.6Very high97.4Very high12 Ų1267.3 Ų67.35%0.05336%0.359CS..Hα-helixtrans-75.3-38.2176.5-178.4-111000112.4I291 E292 Q296 S297 K333 L335 N349 K351I291-F294 WeakPolarHBondContact O-CA 3.41Å; I291-F294 WeakPolarHBondContact O-CB 3.44Å; I291-F294 PolarHBondContact O-N 3.01Å; E292-F294 PolarHBondContact O-N 3.1Å; F294-Q296 VanDerWaalsContact C-N 3.34Å; F294-S297 PolarHBondContact O-N 3.41Å; F294-S297 PolarHBondContact O-OG 2.64Å; F294-K333 HydrophobicContact CE1-CB 3.89Å; F294-K333 HydrophobicContact CE2-CB 4.46Å; F294-K333 HydrophobicContact CE2-CD 3.88Å; F294-K333 HydrophobicContact CE2-CG 4.35Å; F294-K333 HydrophobicContact CZ-CB 3.87Å; F294-K333 HydrophobicContact CZ-CD 3.94Å; F294-K333 HydrophobicContact CZ-CG 4.24Å; F294-L335 HydrophobicContact CD1-CD1 4.15Å; F294-L335 HydrophobicContact CD1-CD2 4.4Å; F294-L335 HydrophobicContact CD1-CG 4.03Å; F294-L335 HydrophobicContact CE1-CD1 4.13Å; F294-L335 HydrophobicContact CE1-CG 4.02Å; F294-N349 WeakPolarHBondContact CZ-O 3.43Å; F294-K351 HydrophobicContact CB-CD 4.27Å; F294-K351 HydrophobicContact CD1-CB 4.44Å; F294-K351 HydrophobicContact CD1-CD 3.86Å; F294-K351 HydrophobicContact CD1-CG 4.35Å; F294-K351 HydrophobicContact CD2-CD 3.5Å; F294-K351 VanDerWaalsContact CD2-CD 3.5Å; F294-K351 HydrophobicContact CD2-CG 4.11Å; F294-K351 VanDerWaalsContact CD2-NZ 3.33Å; F294-K351 HydrophobicContact CE1-CB 3.9Å; F294-K351 HydrophobicContact CE1-CD 3.96Å; F294-K351 HydrophobicContact CE1-CG 3.93Å; F294-K351 HydrophobicContact CE2-CB 4.49Å; F294-K351 HydrophobicContact CE2-CD 3.59Å; F294-K351 VanDerWaalsContact CE2-CE 3.47Å; F294-K351 HydrophobicContact CE2-CG 3.65Å; F294-K351 HydrophobicContact CG-CD 3.6Å; F294-K351 HydrophobicContact CG-CG 4.41Å; F294-K351 HydrophobicContact CZ-CB 3.91Å; F294-K351 HydrophobicContact CZ-CD 3.81Å; F294-K351 HydrophobicContact CZ-CG 3.54Å
295V98.1Very high97.5Very high0 Ų065.2 Ų65.20%034%0.341CS..Hα-helixtrans-62.2-44174.6169.40000110.6L287 I291 E292 S297 S298 I303 L335 L361 H364 K366L287-V295 HydrophobicContact CD1-CG2 4.06Å; I291-V295 HydrophobicContact CG2-CG2 4.31Å; I291-V295 WeakPolarHBondContact O-CG2 3.2Å; I291-V295 PolarHBondContact O-N 3.32Å; E292-V295 PolarHBondContact O-N 3.11Å; E292-V295 VanDerWaalsContact O-N 3.08Å; V295-S297 VanDerWaalsContact C-N 3.33Å; V295-S297 PolarHBondContact O-N 3.24Å; V295-S298 WeakPolarHBondContact O-CB 3.28Å; V295-S298 PolarHBondContact O-N 2.99Å; V295-S298 PolarHBondContact O-OG 3.29Å; V295-I303 HydrophobicContact CB-CD1 4.46Å; V295-I303 HydrophobicContact CB-CG2 4.28Å; V295-I303 HydrophobicContact CG1-CD1 3.93Å; V295-I303 HydrophobicContact CG1-CG2 3.95Å; V295-I303 HydrophobicContact CG2-CD1 3.79Å; V295-I303 HydrophobicContact CG2-CG2 4.32Å; V295-L335 HydrophobicContact CG2-CD1 4.18Å; V295-L335 HydrophobicContact CG2-CD2 4.4Å; V295-L361 HydrophobicContact CG2-CD2 4.06Å; V295-H364 WeakPolarHBondContact CG1-CE1 3.36Å; V295-H364 WeakPolarHBondContact CG1-ND1 3.41Å; V295-K366 HydrophobicContact CG1-CB 4.22Å; V295-K366 HydrophobicContact CG1-CD 4.22Å
296Q97.9Very high97.6Very high92 Ų9258.7 Ų58.743%0.4331%0.313SS..Hα-helixtrans-67.4-29.7179.9-66.6-61-19.300113.4E292 F294 S298 G299E292-Q296 HydrophobicContact CG-CG 4.37Å; E292-Q296 WeakPolarHBondContact O-CG 3.47Å; E292-Q296 PolarHBondContact O-N 3.28Å; E292-Q296 WeakPolarHBondContact OE1-CG 3.42Å; E292-Q296 PolarHBondContact OE1-NE2 2.87Å; F294-Q296 VanDerWaalsContact C-N 3.34Å; Q296-S298 PolarHBondContact O-N 3.24Å; Q296-S298 VanDerWaalsContact O-N 3.09Å; Q296-G299 PolarHBondContact O-N 3.05Å
297S97.6Very high97.6Very high71 Ų7152.6 Ų52.650%0.49727%0.274SS..THydrogen-bonded Turntrans-71.90.2177.275.20000114.5K293 F294 V295 G299K293-S297 PolarHBondContact O-N 3.47Å; F294-S297 PolarHBondContact O-N 3.41Å; F294-S297 PolarHBondContact O-OG 2.64Å; V295-S297 VanDerWaalsContact C-N 3.33Å; V295-S297 PolarHBondContact O-N 3.24Å; S297-G299 VanDerWaalsContact C-N 3.3Å
298S97.7Very high97.5Very high10 Ų1052.2 Ų52.27%0.0727%0.272CS..THydrogen-bonded Turntrans-77.6-9.3174.265.80000114.8V295 Q296 D300 A301 G302V295-S298 WeakPolarHBondContact O-CB 3.28Å; V295-S298 PolarHBondContact O-N 2.99Å; V295-S298 PolarHBondContact O-OG 3.29Å; Q296-S298 PolarHBondContact O-N 3.24Å; Q296-S298 VanDerWaalsContact O-N 3.09Å; S298-D300 PolarHBondContact O-N 3.27Å; S298-A301 PolarHBondContact O-N 2.8Å; S298-G302 VanDerWaalsContact CB-O 3.22Å; S298-G302 WeakPolarHBondContact CB-O 3.49Å; S298-G302 WeakPolarHBondContact OG-CA 3.27Å
299G96.1Very high97.1Very high36 Ų3649.1 Ų49.137%0.37125%0.253SS..THydrogen-bonded Turntrans56.1-139.3-177.500000111.7Q296 S297 K366Q296-G299 PolarHBondContact O-N 3.05Å; S297-G299 VanDerWaalsContact C-N 3.3Å; G299-K366 PolarHBondContact O-NZ 2.94Å
300D96.3Very high96.5Very high157 Ų15741 Ų4184%0.8422%0.221SC*.THydrogen-bonded Turntrans-80.5-20.8-179.4-63-29.4000113.4S298 G302S298-D300 PolarHBondContact O-N 3.27Å; D300-G302 PolarHBondContact O-N 3Å
301A97.8Very high96Very high30 Ų3034.7 Ų34.725%0.24819%0.194CC..THydrogen-bonded Turntrans-60.3-34.5177.200000111.4S298 P331 Q332 K368S298-A301 PolarHBondContact O-N 2.8Å; A301-P331 HydrophobicContact CB-CB 4.1Å; A301-P331 HydrophobicContact CB-CG 4.5Å; A301-Q332 WeakPolarHBondContact O-CG 3.38Å; A301-Q332 PolarHBondContact O-NE2 3.07Å; A301-K368 WeakPolarHBondContact O-CG 3.26Å
302G98.5Very high95.5Very high1 Ų134.4 Ų34.41%0.0119%0.194CC..  trans77.6-166.1178.200000113.5S298 D300 Q332 K333 K366S298-G302 VanDerWaalsContact CB-O 3.22Å; S298-G302 WeakPolarHBondContact CB-O 3.49Å; S298-G302 WeakPolarHBondContact OG-CA 3.27Å; D300-G302 PolarHBondContact O-N 3Å; G302-Q332 WeakPolarHBondContact O-CA 3.41Å; G302-Q332 WeakPolarHBondContact O-CB 3.26Å; G302-K333 PolarHBondContact O-N 3.02Å; G302-K333 VanDerWaalsContact O-N 3.13Å; G302-K366 CarbonylContact C-O 3.58Å; G302-K366 VanDerWaalsContact CA-O 3.28Å; G302-K366 WeakPolarHBondContact CA-O 3.34Å
303I98.8Very high94.9Very high0 Ų037.9 Ų37.90%021%0.208CC..EExtended strand (participates in β ladder)trans-117.8155.3-173.672.6174.9000113.2V295 K333 L335 L361 K366 T367 K368V295-I303 HydrophobicContact CB-CD1 4.46Å; V295-I303 HydrophobicContact CB-CG2 4.28Å; V295-I303 HydrophobicContact CG1-CD1 3.93Å; V295-I303 HydrophobicContact CG1-CG2 3.95Å; V295-I303 HydrophobicContact CG2-CD1 3.79Å; V295-I303 HydrophobicContact CG2-CG2 4.32Å; I303-K333 CarbonylContact C-O 3.5Å; I303-K333 WeakPolarHBondContact CA-O 3.46Å; I303-K333 WeakPolarHBondContact CB-O 3.39Å; I303-K333 HydrophobicContact CG2-CB 4.23Å; I303-L335 HydrophobicContact CB-CD1 4.13Å; I303-L335 HydrophobicContact CD1-CD1 3.95Å; I303-L335 HydrophobicContact CG2-CD1 4.37Å; I303-L361 HydrophobicContact CD1-CD2 4.17Å; I303-K366 PolarHBondContact N-O 3.05Å; I303-T367 WeakPolarHBondContact CD1-OG1 3.36Å; I303-T367 WeakPolarHBondContact CG1-OG1 3.42Å; I303-K368 PolarHBondContact O-N 2.73Å
304I98.9Very high94.5Very high0 Ų034.3 Ų34.30%020%0.197CC..EExtended strand (participates in β ladder)trans-116.1131167-62.7162.6000107.8L330 Q332 K333 V334 L335 I371 I428 I432I304-L330 HydrophobicContact CD1-CD1 3.7Å; I304-Q332 HydrophobicContact CD1-CB 3.66Å; I304-Q332 HydrophobicContact CD1-CG 3.94Å; I304-Q332 HydrophobicContact CG1-CB 3.87Å; I304-Q332 HydrophobicContact CG1-CG 3.99Å; I304-K333 PolarHBondContact N-O 3.09Å; I304-V334 HydrophobicContact CB-CG1 4.45Å; I304-V334 HydrophobicContact CB-CG2 4.26Å; I304-V334 HydrophobicContact CD1-CG2 4.32Å; I304-V334 HydrophobicContact CG2-CG1 4.48Å; I304-V334 WeakPolarHBondContact O-CA 3.39Å; I304-L335 PolarHBondContact O-N 3.13Å; I304-I371 HydrophobicContact CG2-CD1 3.7Å; I304-I371 HydrophobicContact CG2-CG1 3.77Å; I304-I428 HydrophobicContact CD1-CG2 3.61Å; I304-I432 HydrophobicContact CD1-CD1 4.06Å; I304-I432 HydrophobicContact CG1-CD1 4.14Å
305V98.9Very high94.4Very high0 Ų034.3 Ų34.30%020%0.197CC..EExtended strand (participates in β ladder)trans-95132.8170.1-177.40000107.2M356 Q358 L361 L362 T367 A369 F370 I371V305-M356 HydrophobicContact CG1-CE 3.6Å; V305-M356 HydrophobicContact CG1-SD 4.22Å; V305-Q358 HydrophobicContact CG1-CG 4.43Å; V305-L361 HydrophobicContact CG2-CB 3.74Å; V305-L362 HydrophobicContact CB-CD2 4.14Å; V305-L362 HydrophobicContact CG1-CD2 4.43Å; V305-L362 HydrophobicContact CG2-CD2 4.21Å; V305-T367 HydrophobicContact CG2-CG2 4.09Å; V305-A369 PolarHBondContact N-O 2.88Å; V305-F370 HydrophobicContact CB-CD2 3.99Å; V305-F370 HydrophobicContact CG1-CD2 3.98Å; V305-F370 HydrophobicContact CG1-CE2 4.05Å; V305-F370 CarbonylContact O-C 3.57Å; V305-F370 WeakPolarHBondContact O-CA 3.45Å; V305-F370 WeakPolarHBondContact O-CD2 3.17Å; V305-I371 PolarHBondContact O-N 2.64Å
306F98.6Very high94.2Very high0 Ų037.1 Ų37.10%021%0.214CC..EExtended strand (participates in β ladder)trans-130.8117.1178.6179.2-162.4000111.2L308 I323 L327 V334 L335 W336 R337 M356 I371F306-L308 HydrophobicContact CE2-CD1 4.32Å; F306-L308 HydrophobicContact CE2-CD2 3.75Å; F306-L308 HydrophobicContact CE2-CG 3.74Å; F306-L308 HydrophobicContact CZ-CD1 4.35Å; F306-L308 HydrophobicContact CZ-CD2 4.47Å; F306-L308 HydrophobicContact CZ-CG 4.26Å; F306-I323 HydrophobicContact CD1-CG2 4.38Å; F306-I323 HydrophobicContact CE1-CG2 3.44Å; F306-I323 VanDerWaalsContact CE1-CG2 3.44Å; F306-I323 HydrophobicContact CZ-CD1 4.38Å; F306-I323 HydrophobicContact CZ-CG2 4.04Å; F306-L327 HydrophobicContact CD1-CD1 3.97Å; F306-L327 HydrophobicContact CE1-CD1 4.29Å; F306-V334 HydrophobicContact CB-CG1 4.32Å; F306-L335 PolarHBondContact N-O 3.01Å; F306-W336 HydrophobicContact CB-CB 4.24Å; F306-W336 HydrophobicContact CB-CG 4.29Å; F306-W336 HydrophobicContact CD1-CB 4.06Å; F306-W336 AromaticContact CD1-CD1 3.23Å; F306-W336 AromaticContact CD1-CD2 3.58Å; F306-W336 HydrophobicContact CD1-CD2 3.58Å; F306-W336 AromaticContact CD1-CE2 3.62Å; F306-W336 HydrophobicContact CD1-CE3 4.36Å; F306-W336 AromaticContact CD1-CG 3.38Å; F306-W336 HydrophobicContact CD1-CG 3.38Å; F306-W336 HydrophobicContact CD1-CZ2 4.43Å; F306-W336 AromaticContact CD1-NE1 3.4Å; F306-W336 AromaticContact CE1-CD1 3.55Å; F306-W336 AromaticContact CE1-CD2 3.62Å; F306-W336 HydrophobicContact CE1-CD2 3.62Å; F306-W336 AromaticContact CE1-CE2 3.19Å; F306-W336 HydrophobicContact CE1-CE3 4.34Å; F306-W336 AromaticContact CE1-CG 3.87Å; F306-W336 HydrophobicContact CE1-CG 3.87Å; F306-W336 HydrophobicContact CE1-CH2 4.33Å; F306-W336 AromaticContact CE1-CZ2 3.61Å; F306-W336 HydrophobicContact CE1-CZ2 3.61Å; F306-W336 AromaticContact CE1-NE1 3.15Å; F306-W336 AromaticContact CG-CD1 3.6Å; F306-W336 HydrophobicContact CG-CG 4.03Å; F306-W336 AromaticContact CZ-CE2 3.94Å; F306-W336 HydrophobicContact CZ-CZ2 4.21Å; F306-W336 AromaticContact CZ-NE1 3.6Å; F306-W336 CarbonylContact O-C 3.57Å; F306-W336 WeakPolarHBondContact O-CA 3.15Å; F306-R337 PolarHBondContact O-N 3.32Å; F306-M356 WeakPolarHBondContact O-CE 3.21Å; F306-I371 WeakPolarHBondContact CA-O 3.46Å; F306-I371 HydrophobicContact CB-CB 3.99Å; F306-I371 HydrophobicContact CB-CD1 4.31Å; F306-I371 HydrophobicContact CD1-CD1 4.49Å; F306-I371 HydrophobicContact CD2-CB 3.51Å; F306-I371 HydrophobicContact CD2-CG2 3.35Å; F306-I371 WeakPolarHBondContact CD2-O 3.09Å; F306-I371 HydrophobicContact CE2-CB 4.21Å; F306-I371 HydrophobicContact CE2-CG2 3.52Å; F306-I371 HydrophobicContact CG-CB 3.83Å; F306-I371 HydrophobicContact CG-CD1 4.26Å; F306-I371 HydrophobicContact CG-CG2 3.99Å; F306-I371 HydrophobicContact CZ-CG2 4.24Å
307S97.7Very high94.1Very high3 Ų336 Ų362%0.02121%0.214CC..EExtended strand (participates in β ladder)trans-145129.5-179-172.30000112.1G309 Q358 I371 T372 H373S307-G309 PolarHBondContact OG-N 2.75Å; S307-Q358 PolarHBondContact OG-OE1 3.3Å; S307-I371 PolarHBondContact N-O 2.98Å; S307-T372 WeakPolarHBondContact O-CA 3.34Å; S307-H373 PolarHBondContact O-N 3.46Å
308L95.4Very high94.1Very high8 Ų839.5 Ų39.54%0.04222%0.222CC..  trans-97.621172.8-63.1178.6000113.5F306 V312 L315 H373 I392 M394F306-L308 HydrophobicContact CE2-CD1 4.32Å; F306-L308 HydrophobicContact CE2-CD2 3.75Å; F306-L308 HydrophobicContact CE2-CG 3.74Å; F306-L308 HydrophobicContact CZ-CD1 4.35Å; F306-L308 HydrophobicContact CZ-CD2 4.47Å; F306-L308 HydrophobicContact CZ-CG 4.26Å; L308-V312 HydrophobicContact CB-CB 3.99Å; L308-V312 HydrophobicContact CB-CG1 4.12Å; L308-V312 HydrophobicContact CD1-CG1 4.19Å; L308-L315 HydrophobicContact CD1-CD1 3.92Å; L308-L315 HydrophobicContact CD1-CD2 4Å; L308-L315 HydrophobicContact CD1-CG 4.21Å; L308-H373 HydrophobicContact CB-CB 4.3Å; L308-H373 HydrophobicContact CD2-CB 3.89Å; L308-H373 PolarHBondContact O-CD2 2.97Å; L308-I392 HydrophobicContact CD2-CB 4.49Å; L308-M394 HydrophobicContact CD1-CE 4.34Å; L308-M394 HydrophobicContact CD1-SD 4.19Å; L308-M394 HydrophobicContact CD2-CE 4.05Å; L308-M394 HydrophobicContact CD2-CG 4.45Å
309G89.9Confident94Very high8 Ų840.1 Ų40.18%0.08222%0.224CC..THydrogen-bonded Turntrans80.6168.1174.700000113.9S307 M311 R337S307-G309 PolarHBondContact OG-N 2.75Å; G309-M311 PolarHBondContact O-N 2.79Å; G309-M311 VanDerWaalsContact O-N 3.12Å; G309-R337 PolarHBondContact O-NH1 3.41Å
310S82.8Confident94.1Very high23 Ų2338.4 Ų38.416%0.16121%0.206CC..THydrogen-bonded Turntrans-56.9-30.1-169.849.60000114.2R337S310-R337 PolarHBondContact O-NH2 2.81Å
311M84.2Confident94.2Very high40 Ų4032.3 Ų32.320%0.19717%0.174CC..THydrogen-bonded Turntrans-85.9-36.4-168.7-78.7-175.8179.400114.6A31 F88 G309 K313 F395A31-M311 HydrophobicContact CB-CE 3.23Å; A31-M311 HydrophobicContact CB-CG 4.49Å; F88-M311 HydrophobicContact CE1-CB 4.32Å; F88-M311 HydrophobicContact CE1-CG 4.36Å; F88-M311 HydrophobicContact CE2-CE 3.92Å; F88-M311 HydrophobicContact CE2-CG 4.01Å; F88-M311 HydrophobicContact CE2-SD 3.55Å; F88-M311 VanDerWaalsContact CE2-SD 3.55Å; F88-M311 HydrophobicContact CZ-CB 3.62Å; F88-M311 HydrophobicContact CZ-CE 4.31Å; F88-M311 HydrophobicContact CZ-CG 3.41Å; F88-M311 VanDerWaalsContact CZ-CG 3.41Å; F88-M311 HydrophobicContact CZ-SD 3.52Å; F88-M311 VanDerWaalsContact CZ-SD 3.52Å; G309-M311 PolarHBondContact O-N 2.79Å; G309-M311 VanDerWaalsContact O-N 3.12Å; M311-K313 PolarHBondContact O-N 2.66Å; M311-F395 HydrophobicContact CB-CE1 4.33Å; M311-F395 HydrophobicContact CB-CZ 4.02Å; M311-F395 HydrophobicContact CG-CZ 4.39Å; M311-F395 HydrophobicContact SD-CE2 3.78Å; M311-F395 HydrophobicContact SD-CZ 3.48Å; M311-F395 WeakPolarHBondContact SD-CZ 3.4Å
312V87.8Confident94.2Very high12 Ų1232.2 Ų32.27%0.07317%0.168CC..  trans-93.1101.4179.9-178.20000108.8M96 L308 N314 L315 M394 F395M96-V312 HydrophobicContact CE-CG1 4.04Å; M96-V312 HydrophobicContact CE-CG2 4.48Å; M96-V312 HydrophobicContact SD-CG2 4.09Å; L308-V312 HydrophobicContact CB-CB 3.99Å; L308-V312 HydrophobicContact CB-CG1 4.12Å; L308-V312 HydrophobicContact CD1-CG1 4.19Å; V312-N314 WeakPolarHBondContact CG1-O 3.3Å; V312-L315 HydrophobicContact CG1-CD2 4.13Å; V312-M394 HydrophobicContact CG2-CB 4.43Å; V312-M394 HydrophobicContact CG2-CG 4.35Å; V312-F395 HydrophobicContact CG2-CD1 4.43Å; V312-F395 HydrophobicContact CG2-CE1 3.99Å
313K85.3Confident94.2Very high123 Ų12332.2 Ų32.254%0.53517%0.168SC..  trans-85.8-31.7-178.8-66.2-178.4-177.91730112.9M311 S339M311-K313 PolarHBondContact O-N 2.66Å; K313-S339 PolarHBondContact O-N 3.02Å
314N89.5Confident94.2Very high94 Ų9432.2 Ų32.250%0.50317%0.168SC..  trans-147.4174.3-176.2644.8000111.2V312 Y338 G340V312-N314 WeakPolarHBondContact CG1-O 3.3Å; N314-Y338 HydrophobicContact CB-CE2 4.29Å; N314-G340 VanDerWaalsContact CB-CA 3.43Å
315L94.2Very high94.2Very high12 Ų1233.7 Ų33.76%0.06318%0.178CC..  trans-134166.5175.2-63.8174.4000107.8M96 L308 V312 K319 A320 I323 Y338 M394 L416M96-L315 HydrophobicContact CE-CD2 3.78Å; L308-L315 HydrophobicContact CD1-CD1 3.92Å; L308-L315 HydrophobicContact CD1-CD2 4Å; L308-L315 HydrophobicContact CD1-CG 4.21Å; V312-L315 HydrophobicContact CG1-CD2 4.13Å; L315-K319 HydrophobicContact CB-CB 4.36Å; L315-A320 HydrophobicContact CB-CB 4.43Å; L315-I323 HydrophobicContact CD1-CD1 3.46Å; L315-I323 VanDerWaalsContact CD1-CD1 3.46Å; L315-Y338 HydrophobicContact CB-CE2 4.36Å; L315-M394 HydrophobicContact CD2-SD 4.48Å; L315-L416 HydrophobicContact CD2-CD1 4.46Å
316T95.1Very high94.2Very high59 Ų5933.7 Ų33.736%0.36218%0.178SC..  trans-56.6148.6169.368.30000110.5Y97 E318 K319 A320Y97-T316 HydrophobicContact CE1-CG2 3.82Å; T316-E318 PolarHBondContact O-N 2.89Å; T316-K319 PolarHBondContact O-N 3.19Å; T316-K319 VanDerWaalsContact O-N 3.15Å; T316-K319 VanDerWaalsContact OG1-CG 3.3Å; T316-K319 WeakPolarHBondContact OG1-CG 3.46Å; T316-K319 PolarHBondContact OG1-N 2.85Å; T316-A320 WeakPolarHBondContact O-CB 3.46Å; T316-A320 PolarHBondContact O-N 3.12Å
317T96.3Very high94.2Very high68 Ų6833.7 Ų33.742%0.41718%0.178SC..Hα-helixtrans-53.8-40.8-179.6-53.60000111.7A320 N321T317-A320 PolarHBondContact O-N 3.39Å; T317-N321 VanDerWaalsContact O-CB 3.29Å; T317-N321 WeakPolarHBondContact O-CB 3.22Å; T317-N321 VanDerWaalsContact O-CG 3.29Å; T317-N321 PolarHBondContact O-N 3.2Å
318E96.4Very high94.3Very high145 Ų14535.6 Ų35.668%0.67820%0.195SC*.Hα-helixtrans-60.4-51.8177.5-172.6-167.3153.500112T316 A320 N321 M322T316-E318 PolarHBondContact O-N 2.89Å; E318-A320 VanDerWaalsContact C-N 3.35Å; E318-A320 PolarHBondContact O-N 3.32Å; E318-N321 PolarHBondContact O-N 3.5Å; E318-M322 WeakPolarHBondContact O-CB 3Å; E318-M322 PolarHBondContact O-N 3.5Å
319K96.6Very high94.4Very high23 Ų2339.4 Ų39.410%0.121%0.212CC..Hα-helixtrans-65.8-39.4179.8-65.2-64.3-179.2-178.40111.5L315 T316 M322 I323 L416 N417L315-K319 HydrophobicContact CB-CB 4.36Å; T316-K319 PolarHBondContact O-N 3.19Å; T316-K319 VanDerWaalsContact O-N 3.15Å; T316-K319 VanDerWaalsContact OG1-CG 3.3Å; T316-K319 WeakPolarHBondContact OG1-CG 3.46Å; T316-K319 PolarHBondContact OG1-N 2.85Å; K319-M322 HydrophobicContact CD-CE 3.68Å; K319-M322 PolarHBondContact O-N 2.88Å; K319-I323 WeakPolarHBondContact O-CD1 3.39Å; K319-I323 VanDerWaalsContact O-CG1 3.25Å; K319-I323 WeakPolarHBondContact O-CG1 3.39Å; K319-I323 PolarHBondContact O-N 2.82Å; K319-L416 HydrophobicContact CB-CD1 4.42Å; K319-L416 HydrophobicContact CD-CD1 4.32Å; K319-L416 WeakPolarHBondContact CD-O 3.42Å; K319-L416 VanDerWaalsContact CE-O 3.28Å; K319-L416 WeakPolarHBondContact CE-O 3.28Å; K319-L416 HydrophobicContact CG-CD1 4.35Å; K319-L416 PolarHBondContact NZ-O 3.4Å; K319-N417 PolarHBondContact NZ-O 3.24Å
320A97.8Very high94.8Very high0 Ų039.4 Ų39.40%021%0.21CC..Hα-helixtrans-64.4-42.3177.300000112L315 T316 T317 E318 A324 Y338 P343L315-A320 HydrophobicContact CB-CB 4.43Å; T316-A320 WeakPolarHBondContact O-CB 3.46Å; T316-A320 PolarHBondContact O-N 3.12Å; T317-A320 PolarHBondContact O-N 3.39Å; E318-A320 VanDerWaalsContact C-N 3.35Å; E318-A320 PolarHBondContact O-N 3.32Å; A320-A324 VanDerWaalsContact O-CB 3.24Å; A320-A324 WeakPolarHBondContact O-CB 3.35Å; A320-A324 PolarHBondContact O-N 3.36Å; A320-Y338 HydrophobicContact CB-CE2 4.28Å; A320-Y338 WeakPolarHBondContact CB-OH 3.25Å; A320-P343 HydrophobicContact CB-CG 4.08Å
321N98.3Very high95.5Very high30 Ų3042.8 Ų42.816%0.1623%0.232CC..Hα-helixtrans-66.2-42.7174.8-77.6-16.3000111.9T317 E318 I323 A324 S325 P343 D344 T345T317-N321 VanDerWaalsContact O-CB 3.29Å; T317-N321 WeakPolarHBondContact O-CB 3.22Å; T317-N321 VanDerWaalsContact O-CG 3.29Å; T317-N321 PolarHBondContact O-N 3.2Å; E318-N321 PolarHBondContact O-N 3.5Å; N321-I323 PolarHBondContact O-N 3.49Å; N321-A324 PolarHBondContact O-N 3.03Å; N321-S325 WeakPolarHBondContact O-CB 3.36Å; N321-S325 PolarHBondContact O-N 3.35Å; N321-S325 PolarHBondContact O-OG 3.01Å; N321-P343 WeakPolarHBondContact OD1-CA 3.41Å; N321-P343 VanDerWaalsContact OD1-CB 3.32Å; N321-P343 WeakPolarHBondContact OD1-CB 3.49Å; N321-D344 PolarHBondContact ND2-OD2 2.7Å; N321-D344 VanDerWaalsContact ND2-OD2 3.12Å; N321-D344 PolarHBondContact OD1-N 2.87Å; N321-T345 WeakPolarHBondContact CA-OG1 3.34Å; N321-T345 PolarHBondContact O-OG1 3.44Å
322M98.4Very high96.2Very high27 Ų2741.6 Ų41.613%0.13323%0.226CC..Hα-helixtrans-59.8-46.5175.7173-96.5-71.600111.7E318 K319 S325 A326 M419E318-M322 WeakPolarHBondContact O-CB 3Å; E318-M322 PolarHBondContact O-N 3.5Å; K319-M322 HydrophobicContact CD-CE 3.68Å; K319-M322 PolarHBondContact O-N 2.88Å; M322-S325 PolarHBondContact O-N 3.35Å; M322-A326 PolarHBondContact O-N 3.14Å; M322-A326 VanDerWaalsContact O-N 3.15Å; M322-M419 HydrophobicContact CE-CE 3.6Å; M322-M419 HydrophobicContact CE-CG 3.67Å; M322-M419 WeakPolarHBondContact CE-O 3.29Å; M322-M419 HydrophobicContact CE-SD 4.5Å; M322-M419 HydrophobicContact SD-CE 3.99Å; M322-M419 HydrophobicContact SD-CG 4.09Å
323I98.6Very high96.8Very high1 Ų143.3 Ų43.31%0.00523%0.232CC..Hα-helixtrans-64.6-46.4177-65.3162.6000111F306 L315 K319 N321 S325 A326 L327 W336 M419 L424F306-I323 HydrophobicContact CD1-CG2 4.38Å; F306-I323 HydrophobicContact CE1-CG2 3.44Å; F306-I323 VanDerWaalsContact CE1-CG2 3.44Å; F306-I323 HydrophobicContact CZ-CD1 4.38Å; F306-I323 HydrophobicContact CZ-CG2 4.04Å; L315-I323 HydrophobicContact CD1-CD1 3.46Å; L315-I323 VanDerWaalsContact CD1-CD1 3.46Å; K319-I323 WeakPolarHBondContact O-CD1 3.39Å; K319-I323 VanDerWaalsContact O-CG1 3.25Å; K319-I323 WeakPolarHBondContact O-CG1 3.39Å; K319-I323 PolarHBondContact O-N 2.82Å; N321-I323 PolarHBondContact O-N 3.49Å; I323-S325 VanDerWaalsContact C-N 3.29Å; I323-S325 PolarHBondContact O-N 3.2Å; I323-A326 WeakPolarHBondContact O-CB 3.29Å; I323-A326 PolarHBondContact O-N 3.32Å; I323-A326 VanDerWaalsContact O-N 3.08Å; I323-L327 HydrophobicContact CG2-CD1 3.85Å; I323-L327 HydrophobicContact CG2-CG 4.2Å; I323-L327 VanDerWaalsContact O-CG 3.3Å; I323-L327 WeakPolarHBondContact O-CG 3.44Å; I323-L327 PolarHBondContact O-N 3.19Å; I323-W336 HydrophobicContact CB-CH2 4.21Å; I323-W336 HydrophobicContact CG2-CH2 4.01Å; I323-W336 HydrophobicContact CG2-CZ2 4.29Å; I323-W336 HydrophobicContact CG2-CZ3 4.38Å; I323-M419 HydrophobicContact CD1-CE 3.68Å; I323-M419 HydrophobicContact CG1-CE 3.57Å; I323-L424 HydrophobicContact CB-CD2 4.21Å; I323-L424 HydrophobicContact CG1-CD2 3.97Å; I323-L424 HydrophobicContact CG2-CD2 3.88Å
324A98.6Very high97.4Very high0 Ų037.4 Ų37.40%021%0.207CC..Hα-helixtrans-58.4-40.9178.200000112.4A320 N321 A326 L327 A328 W336 P343 L346A320-A324 VanDerWaalsContact O-CB 3.24Å; A320-A324 WeakPolarHBondContact O-CB 3.35Å; A320-A324 PolarHBondContact O-N 3.36Å; N321-A324 PolarHBondContact O-N 3.03Å; A324-A326 VanDerWaalsContact C-N 3.32Å; A324-A326 PolarHBondContact O-N 3.13Å; A324-L327 PolarHBondContact O-N 3.11Å; A324-A328 WeakPolarHBondContact O-CB 3.29Å; A324-A328 PolarHBondContact O-N 3.34Å; A324-W336 HydrophobicContact CB-CZ3 4.16Å; A324-P343 HydrophobicContact CB-CB 3.51Å; A324-P343 HydrophobicContact CB-CG 4Å; A324-L346 HydrophobicContact CB-CD1 4.49Å
325S98.7Very high97.8Very high31 Ų3133 Ų3322%0.21718%0.183CC..Hα-helixtrans-61.6-37.6174.8-65.80000112.6N321 M322 I323 Q329 T345N321-S325 WeakPolarHBondContact O-CB 3.36Å; N321-S325 PolarHBondContact O-N 3.35Å; N321-S325 PolarHBondContact O-OG 3.01Å; M322-S325 PolarHBondContact O-N 3.35Å; I323-S325 VanDerWaalsContact C-N 3.29Å; I323-S325 PolarHBondContact O-N 3.2Å; S325-Q329 WeakPolarHBondContact O-CG 3.28Å; S325-Q329 PolarHBondContact O-NE2 2.95Å; S325-T345 WeakPolarHBondContact OG-CB 3.43Å; S325-T345 WeakPolarHBondContact OG-CG2 3.38Å; S325-T345 PolarHBondContact OG-OG1 3.37Å
326A98.8Very high98Very high0 Ų032.4 Ų32.40%018%0.18CC..Hα-helixtrans-69.1-45.3177.700000110.7M322 I323 A324 A328 Q329 T421 L424 R425M322-A326 PolarHBondContact O-N 3.14Å; M322-A326 VanDerWaalsContact O-N 3.15Å; I323-A326 WeakPolarHBondContact O-CB 3.29Å; I323-A326 PolarHBondContact O-N 3.32Å; I323-A326 VanDerWaalsContact O-N 3.08Å; A324-A326 VanDerWaalsContact C-N 3.32Å; A324-A326 PolarHBondContact O-N 3.13Å; A326-A328 VanDerWaalsContact C-N 3.32Å; A326-A328 PolarHBondContact O-N 2.93Å; A326-Q329 PolarHBondContact O-N 3.39Å; A326-T421 HydrophobicContact CB-CG2 3.95Å; A326-T421 VanDerWaalsContact CB-O 3.26Å; A326-T421 WeakPolarHBondContact CB-O 3.29Å; A326-L424 HydrophobicContact CB-CB 4.14Å; A326-L424 HydrophobicContact CB-CD2 4.03Å; A326-L424 HydrophobicContact CB-CG 4.16Å; A326-R425 HydrophobicContact CB-CB 4.43Å
327L98.8Very high98.1Very high0 Ų031 Ų310%017%0.168CC..Hα-helixtrans-63.4-37.7179-63.9174.1000111.9F306 I323 A324 Q329 L330 V334 W336 N349 T350 I371 I428F306-L327 HydrophobicContact CD1-CD1 3.97Å; F306-L327 HydrophobicContact CE1-CD1 4.29Å; I323-L327 HydrophobicContact CG2-CD1 3.85Å; I323-L327 HydrophobicContact CG2-CG 4.2Å; I323-L327 VanDerWaalsContact O-CG 3.3Å; I323-L327 WeakPolarHBondContact O-CG 3.44Å; I323-L327 PolarHBondContact O-N 3.19Å; A324-L327 PolarHBondContact O-N 3.11Å; L327-Q329 PolarHBondContact O-N 3.44Å; L327-L330 HydrophobicContact CD2-CD1 4.32Å; L327-L330 WeakPolarHBondContact O-CB 3.45Å; L327-L330 PolarHBondContact O-N 2.82Å; L327-L330 VanDerWaalsContact O-N 3.15Å; L327-V334 HydrophobicContact CB-CG2 4.34Å; L327-V334 HydrophobicContact CD1-CG1 4.08Å; L327-V334 HydrophobicContact CD2-CG1 4.15Å; L327-V334 HydrophobicContact CD2-CG2 4.13Å; L327-W336 HydrophobicContact CD1-CD2 4.46Å; L327-W336 HydrophobicContact CD1-CE3 3.89Å; L327-W336 HydrophobicContact CD1-CZ3 4.18Å; L327-N349 PolarHBondContact O-ND2 2.95Å; L327-T350 HydrophobicContact CD1-CG2 4.43Å; L327-I371 HydrophobicContact CD2-CD1 3.72Å; L327-I428 HydrophobicContact CD2-CD1 4.04Å
328A98.6Very high98.2Very high44 Ų4428.3 Ų28.336%0.36415%0.15SC..Hα-helixtrans-62.6-22.5178.500000113.7A324 A326 L330A324-A328 WeakPolarHBondContact O-CB 3.29Å; A324-A328 PolarHBondContact O-N 3.34Å; A326-A328 VanDerWaalsContact C-N 3.32Å; A326-A328 PolarHBondContact O-N 2.93Å; A328-L330 VanDerWaalsContact C-N 3.3Å
329Q98.4Very high98Very high87 Ų8723.9 Ų23.941%0.40714%0.135SC..THydrogen-bonded Turntrans-85.10.1179.1-65.617544.200113.6S325 A326 L327 T421 R425S325-Q329 WeakPolarHBondContact O-CG 3.28Å; S325-Q329 PolarHBondContact O-NE2 2.95Å; A326-Q329 PolarHBondContact O-N 3.39Å; L327-Q329 PolarHBondContact O-N 3.44Å; Q329-T421 VanDerWaalsContact NE2-CG2 3.34Å; Q329-R425 HydrophobicContact CB-CG 4.43Å
330L98.4Very high97.8Very high9 Ų923.7 Ų23.75%0.04714%0.139CC..SBendtrans-100.7142.7-176.6-62.1173.2000111.5I304 L327 A328 Q332 N349 R425 I428 K429I304-L330 HydrophobicContact CD1-CD1 3.7Å; L327-L330 HydrophobicContact CD2-CD1 4.32Å; L327-L330 WeakPolarHBondContact O-CB 3.45Å; L327-L330 PolarHBondContact O-N 2.82Å; L327-L330 VanDerWaalsContact O-N 3.15Å; A328-L330 VanDerWaalsContact C-N 3.3Å; L330-Q332 PolarHBondContact O-N 3.24Å; L330-N349 PolarHBondContact O-ND2 3.37Å; L330-R425 HydrophobicContact CD2-CG 4.02Å; L330-I428 HydrophobicContact CD1-CB 4.18Å; L330-I428 HydrophobicContact CD1-CD1 3.77Å; L330-I428 HydrophobicContact CD1-CG2 3.64Å; L330-I428 HydrophobicContact CD2-CG2 4.35Å; L330-K429 HydrophobicContact CD2-CG 4.06Å
331P97.9Very high97.8Very high93 Ų9329.5 Ų29.560%0.60417%0.165SC*.SBendtrans-72.1-17.5175.629.6-35000113.2A301A301-P331 HydrophobicContact CB-CB 4.1Å; A301-P331 HydrophobicContact CB-CG 4.5Å
332Q98.7Very high97.7Very high16 Ų1633.5 Ų33.58%0.07519%0.185CC..SBendtrans-68.4152178.8-71.972.726.900112.3A301 G302 I304 L330 N349 I432A301-Q332 WeakPolarHBondContact O-CG 3.38Å; A301-Q332 PolarHBondContact O-NE2 3.07Å; G302-Q332 WeakPolarHBondContact O-CA 3.41Å; G302-Q332 WeakPolarHBondContact O-CB 3.26Å; I304-Q332 HydrophobicContact CD1-CB 3.66Å; I304-Q332 HydrophobicContact CD1-CG 3.94Å; I304-Q332 HydrophobicContact CG1-CB 3.87Å; I304-Q332 HydrophobicContact CG1-CG 3.99Å; L330-Q332 PolarHBondContact O-N 3.24Å; Q332-N349 PolarHBondContact O-ND2 3.13Å; Q332-I432 HydrophobicContact CG-CD1 4.2Å
333K98.8Very high97.7Very high47 Ų4732.5 Ų32.520%0.20418%0.181CC..EExtended strand (participates in β ladder)trans-80.8137.3161.7-63.8-60.3-173.9-172.40109.9F294 G302 I303 I304 N349F294-K333 HydrophobicContact CE1-CB 3.89Å; F294-K333 HydrophobicContact CE2-CB 4.46Å; F294-K333 HydrophobicContact CE2-CD 3.88Å; F294-K333 HydrophobicContact CE2-CG 4.35Å; F294-K333 HydrophobicContact CZ-CB 3.87Å; F294-K333 HydrophobicContact CZ-CD 3.94Å; F294-K333 HydrophobicContact CZ-CG 4.24Å; G302-K333 PolarHBondContact O-N 3.02Å; G302-K333 VanDerWaalsContact O-N 3.13Å; I303-K333 CarbonylContact C-O 3.5Å; I303-K333 WeakPolarHBondContact CA-O 3.46Å; I303-K333 WeakPolarHBondContact CB-O 3.39Å; I303-K333 HydrophobicContact CG2-CB 4.23Å; I304-K333 PolarHBondContact N-O 3.09Å; K333-N349 CarbonylContact C-O 3.59Å; K333-N349 VanDerWaalsContact CA-O 3.29Å; K333-N349 WeakPolarHBondContact CA-O 3.46Å; K333-N349 HydrophobicContact CD-CB 4.15Å
334V98.8Very high97.6Very high0 Ų037.8 Ų37.80%021%0.209CC..EExtended strand (participates in β ladder)trans-114.5127.8-176.8-173.50000109.8I304 F306 L327 W336 N349 T350 K351I304-V334 HydrophobicContact CB-CG1 4.45Å; I304-V334 HydrophobicContact CB-CG2 4.26Å; I304-V334 HydrophobicContact CD1-CG2 4.32Å; I304-V334 HydrophobicContact CG2-CG1 4.48Å; I304-V334 WeakPolarHBondContact O-CA 3.39Å; F306-V334 HydrophobicContact CB-CG1 4.32Å; L327-V334 HydrophobicContact CB-CG2 4.34Å; L327-V334 HydrophobicContact CD1-CG1 4.08Å; L327-V334 HydrophobicContact CD2-CG1 4.15Å; L327-V334 HydrophobicContact CD2-CG2 4.13Å; V334-W336 HydrophobicContact CG1-CB 4.42Å; V334-N349 PolarHBondContact N-O 3.4Å; V334-T350 HydrophobicContact CB-CG2 3.96Å; V334-T350 HydrophobicContact CG1-CG2 4.15Å; V334-T350 CarbonylContact O-C 3.1Å; V334-T350 WeakPolarHBondContact O-CA 3.41Å; V334-K351 PolarHBondContact O-N 2.72Å
335L98.7Very high97.6Very high0 Ų040.4 Ų40.40%023%0.225CC..EExtended strand (participates in β ladder)trans-104.4108.5168.5-64.391.5000107.6I291 F294 V295 I303 I304 F306 Y353 M356 L361I291-L335 HydrophobicContact CG2-CD2 3.69Å; F294-L335 HydrophobicContact CD1-CD1 4.15Å; F294-L335 HydrophobicContact CD1-CD2 4.4Å; F294-L335 HydrophobicContact CD1-CG 4.03Å; F294-L335 HydrophobicContact CE1-CD1 4.13Å; F294-L335 HydrophobicContact CE1-CG 4.02Å; V295-L335 HydrophobicContact CG2-CD1 4.18Å; V295-L335 HydrophobicContact CG2-CD2 4.4Å; I303-L335 HydrophobicContact CB-CD1 4.13Å; I303-L335 HydrophobicContact CD1-CD1 3.95Å; I303-L335 HydrophobicContact CG2-CD1 4.37Å; I304-L335 PolarHBondContact O-N 3.13Å; F306-L335 PolarHBondContact N-O 3.01Å; L335-Y353 HydrophobicContact CB-CD2 4.43Å; L335-Y353 HydrophobicContact CB-CE2 4.15Å; L335-Y353 HydrophobicContact CD2-CE2 3.83Å; L335-Y353 HydrophobicContact CG-CE2 4.08Å; L335-M356 HydrophobicContact CB-SD 4.27Å; L335-L361 HydrophobicContact CD1-CD2 4.45Å; L335-L361 HydrophobicContact CD2-CD1 3.97Å; L335-L361 HydrophobicContact CD2-CD2 3.7Å
336W98.4Very high97.6Very high1 Ų141.5 Ų41.50%0.00423%0.228CC..EExtended strand (participates in β ladder)trans-112.2118-174.6-179.411.3000109.9F306 I323 A324 L327 V334 Y338 P343 T350 K351 L352 Y353F306-W336 HydrophobicContact CB-CB 4.24Å; F306-W336 HydrophobicContact CB-CG 4.29Å; F306-W336 HydrophobicContact CD1-CB 4.06Å; F306-W336 AromaticContact CD1-CD1 3.23Å; F306-W336 AromaticContact CD1-CD2 3.58Å; F306-W336 HydrophobicContact CD1-CD2 3.58Å; F306-W336 AromaticContact CD1-CE2 3.62Å; F306-W336 HydrophobicContact CD1-CE3 4.36Å; F306-W336 AromaticContact CD1-CG 3.38Å; F306-W336 HydrophobicContact CD1-CG 3.38Å; F306-W336 HydrophobicContact CD1-CZ2 4.43Å; F306-W336 AromaticContact CD1-NE1 3.4Å; F306-W336 AromaticContact CE1-CD1 3.55Å; F306-W336 AromaticContact CE1-CD2 3.62Å; F306-W336 HydrophobicContact CE1-CD2 3.62Å; F306-W336 AromaticContact CE1-CE2 3.19Å; F306-W336 HydrophobicContact CE1-CE3 4.34Å; F306-W336 AromaticContact CE1-CG 3.87Å; F306-W336 HydrophobicContact CE1-CG 3.87Å; F306-W336 HydrophobicContact CE1-CH2 4.33Å; F306-W336 AromaticContact CE1-CZ2 3.61Å; F306-W336 HydrophobicContact CE1-CZ2 3.61Å; F306-W336 AromaticContact CE1-NE1 3.15Å; F306-W336 AromaticContact CG-CD1 3.6Å; F306-W336 HydrophobicContact CG-CG 4.03Å; F306-W336 AromaticContact CZ-CE2 3.94Å; F306-W336 HydrophobicContact CZ-CZ2 4.21Å; F306-W336 AromaticContact CZ-NE1 3.6Å; F306-W336 CarbonylContact O-C 3.57Å; F306-W336 WeakPolarHBondContact O-CA 3.15Å; I323-W336 HydrophobicContact CB-CH2 4.21Å; I323-W336 HydrophobicContact CG2-CH2 4.01Å; I323-W336 HydrophobicContact CG2-CZ2 4.29Å; I323-W336 HydrophobicContact CG2-CZ3 4.38Å; A324-W336 HydrophobicContact CB-CZ3 4.16Å; L327-W336 HydrophobicContact CD1-CD2 4.46Å; L327-W336 HydrophobicContact CD1-CE3 3.89Å; L327-W336 HydrophobicContact CD1-CZ3 4.18Å; V334-W336 HydrophobicContact CG1-CB 4.42Å; W336-Y338 AromaticContact CE2-CD2 3.91Å; W336-Y338 HydrophobicContact CH2-CD2 4.5Å; W336-Y338 AromaticContact CZ2-CD2 3.7Å; W336-Y338 HydrophobicContact CZ2-CD2 3.7Å; W336-Y338 HydrophobicContact CZ2-CE2 4.16Å; W336-Y338 HydrophobicContact CZ2-CG 4.11Å; W336-Y338 PolarHBondContact O-N 2.94Å; W336-P343 HydrophobicContact CH2-CG 4.09Å; W336-P343 HydrophobicContact CZ3-CG 3.97Å; W336-T350 HydrophobicContact CB-CG2 4.16Å; W336-T350 HydrophobicContact CE3-CG2 4.16Å; W336-K351 PolarHBondContact N-O 3.28Å; W336-L352 HydrophobicContact CB-CD2 3.99Å; W336-L352 HydrophobicContact CD2-CD2 3.84Å; W336-L352 HydrophobicContact CE3-CD2 3.52Å; W336-L352 HydrophobicContact CG-CD2 4.08Å; W336-L352 HydrophobicContact CZ3-CD2 4.3Å; W336-L352 CarbonylContact O-C 3.6Å; W336-L352 VanDerWaalsContact O-CA 3.28Å; W336-L352 WeakPolarHBondContact O-CA 3.36Å; W336-Y353 PolarHBondContact O-N 3.18Å
337R97.1Very high97.6Very high28 Ų2842.2 Ų42.211%0.10624%0.236CC..EExtended strand (participates in β ladder)trans-75.4113.4168.4-175.2-171.6168.5-135.9-14110.1F306 G309 S310 Y353 D354 M356F306-R337 PolarHBondContact O-N 3.32Å; G309-R337 PolarHBondContact O-NH1 3.41Å; S310-R337 PolarHBondContact O-NH2 2.81Å; R337-Y353 CarbonylContact C-O 3.45Å; R337-Y353 WeakPolarHBondContact CA-O 3.15Å; R337-Y353 WeakPolarHBondContact CG-O 3.24Å; R337-D354 WeakPolarHBondContact CG-O 3.49Å; R337-D354 PolarHBondContact NE-O 3.11Å; R337-M356 HydrophobicContact CB-CE 3.7Å; R337-M356 HydrophobicContact CB-CG 4.28Å; R337-M356 HydrophobicContact CB-SD 4.21Å
338Y96.6Very high97.5Very high13 Ų1347.9 Ų47.95%0.05128%0.275CS..  trans-162.1129.7-176.2-175.9-97.5000110.3N314 L315 A320 W336 G340 K341 L352 Y353N314-Y338 HydrophobicContact CB-CE2 4.29Å; L315-Y338 HydrophobicContact CB-CE2 4.36Å; A320-Y338 HydrophobicContact CB-CE2 4.28Å; A320-Y338 WeakPolarHBondContact CB-OH 3.25Å; W336-Y338 AromaticContact CE2-CD2 3.91Å; W336-Y338 HydrophobicContact CH2-CD2 4.5Å; W336-Y338 AromaticContact CZ2-CD2 3.7Å; W336-Y338 HydrophobicContact CZ2-CD2 3.7Å; W336-Y338 HydrophobicContact CZ2-CE2 4.16Å; W336-Y338 HydrophobicContact CZ2-CG 4.11Å; W336-Y338 PolarHBondContact O-N 2.94Å; Y338-G340 VanDerWaalsContact CE1-N 3.35Å; Y338-G340 WeakPolarHBondContact CE1-O 3.5Å; Y338-K341 VanDerWaalsContact CE1-O 3.25Å; Y338-K341 WeakPolarHBondContact CE1-O 3.44Å; Y338-K341 PolarHBondContact OH-O 2.83Å; Y338-L352 HydrophobicContact CD1-CD1 4.16Å; Y338-Y353 PolarHBondContact N-O 2.96Å
339S93.4Very high97.5Very high51 Ų5146.5 Ų46.536%0.35726%0.261SS..  trans-120.113.5-177.8-63.20000112.4K313 D354K313-S339 PolarHBondContact O-N 3.02Å; S339-D354 WeakPolarHBondContact CB-OD1 3.48Å; S339-D354 WeakPolarHBondContact OG-CA 3.38Å; S339-D354 PolarHBondContact OG-OD1 3.45Å
340G93.1Very high97.5Very high19 Ų1942.8 Ų42.820%0.19625%0.245CC..SBendtrans-84.4-170.2175.400000113.2N314 Y338 I342N314-G340 VanDerWaalsContact CB-CA 3.43Å; Y338-G340 VanDerWaalsContact CE1-N 3.35Å; Y338-G340 WeakPolarHBondContact CE1-O 3.5Å; G340-I342 PolarHBondContact O-N 2.87Å
341K95.9Very high97.4Very high123 Ų12346.1 Ų46.154%0.53526%0.259SS..SBendtrans-59.4126.8171.2-177.1-168.1170.6-158.30109.5Y338 D344Y338-K341 VanDerWaalsContact CE1-O 3.25Å; Y338-K341 WeakPolarHBondContact CE1-O 3.44Å; Y338-K341 PolarHBondContact OH-O 2.83Å; K341-D344 IonicContact NZ-OD1 2.89Å; K341-D344 PolarHBondContact NZ-OD1 3.48Å; K341-D344 IonicContact NZ-OD2 3.69Å
342I97.3Very high97.4Very high114 Ų11443.9 Ų43.959%0.58524%0.241SC*.PPolyproline II helixtrans-51125.4176.5-61.1174.7000109.4G340 L346 L352G340-I342 PolarHBondContact O-N 2.87Å; I342-L346 HydrophobicContact CG2-CD2 4Å; I342-L352 HydrophobicContact CB-CD1 4.45Å; I342-L352 HydrophobicContact CG1-CD1 4.14Å; I342-L352 HydrophobicContact CG2-CD1 4.22Å
343P97.8Very high97.3Very high6 Ų644.9 Ų44.94%0.03925%0.245CC..PPolyproline II helixtrans-61.2137178.3-23.934.4000111.7A320 N321 A324 W336 T345 L346A320-P343 HydrophobicContact CB-CG 4.08Å; N321-P343 WeakPolarHBondContact OD1-CA 3.41Å; N321-P343 VanDerWaalsContact OD1-CB 3.32Å; N321-P343 WeakPolarHBondContact OD1-CB 3.49Å; A324-P343 HydrophobicContact CB-CB 3.51Å; A324-P343 HydrophobicContact CB-CG 4Å; W336-P343 HydrophobicContact CH2-CG 4.09Å; W336-P343 HydrophobicContact CZ3-CG 3.97Å; P343-T345 PolarHBondContact O-N 2.99Å; P343-L346 HydrophobicContact CB-CB 4.42Å; P343-L346 VanDerWaalsContact O-CB 3.32Å; P343-L346 WeakPolarHBondContact O-CB 3.35Å; P343-L346 PolarHBondContact O-N 3.48Å
344D97.9Very high97Very high111 Ų11148.1 Ų48.159%0.59426%0.264SS*.THydrogen-bonded Turntrans-67-23.5179.8-51.9-54.1000111.4N321 K341N321-D344 PolarHBondContact ND2-OD2 2.7Å; N321-D344 VanDerWaalsContact ND2-OD2 3.12Å; N321-D344 PolarHBondContact OD1-N 2.87Å; K341-D344 IonicContact NZ-OD1 2.89Å; K341-D344 PolarHBondContact NZ-OD1 3.48Å; K341-D344 IonicContact NZ-OD2 3.69Å
345T98.1Very high96.7Very high56 Ų5656.1 Ų56.134%0.34430%0.295SS..THydrogen-bonded Turntrans-99.618.5179.155.30000113.5N321 S325 P343 G347N321-T345 WeakPolarHBondContact CA-OG1 3.34Å; N321-T345 PolarHBondContact O-OG1 3.44Å; S325-T345 WeakPolarHBondContact OG-CB 3.43Å; S325-T345 WeakPolarHBondContact OG-CG2 3.38Å; S325-T345 PolarHBondContact OG-OG1 3.37Å; P343-T345 PolarHBondContact O-N 2.99Å; T345-G347 PolarHBondContact O-N 2.98Å; T345-G347 VanDerWaalsContact O-N 3.14Å
346L98.3Very high96.4Very high54 Ų5456.3 Ų56.328%0.28330%0.296SS..  trans-64.3113.8-179-170.972.6000112A324 I342 P343 T350 L352A324-L346 HydrophobicContact CB-CD1 4.49Å; I342-L346 HydrophobicContact CG2-CD2 4Å; P343-L346 HydrophobicContact CB-CB 4.42Å; P343-L346 VanDerWaalsContact O-CB 3.32Å; P343-L346 WeakPolarHBondContact O-CB 3.35Å; P343-L346 PolarHBondContact O-N 3.48Å; L346-T350 HydrophobicContact CD1-CG2 3.68Å; L346-L352 HydrophobicContact CD1-CD2 4Å; L346-L352 HydrophobicContact CD1-CG 4.36Å; L346-L352 HydrophobicContact CD2-CD1 4.03Å; L346-L352 HydrophobicContact CD2-CG 4.05Å
347G97.8Very high96.3Very high15 Ų1557.8 Ų57.816%0.15531%0.305CS..  trans-71.1152.3175.700000113.8T345 N349 T350T345-G347 PolarHBondContact O-N 2.98Å; T345-G347 VanDerWaalsContact O-N 3.14Å; G347-N349 PolarHBondContact O-N 3.38Å; G347-N349 VanDerWaalsContact O-N 3.09Å; G347-T350 PolarHBondContact O-N 2.9Å
348S96.9Very high96.3Very high119 Ų11958.2 Ų58.283%0.83231%0.309SS*.THydrogen-bonded Turntrans-65.8-10.8178.366.40000114.3T350S348-T350 VanDerWaalsContact C-N 3.35Å
349N98.3Very high96.3Very high14 Ų1458 Ų588%0.07531%0.308CS..THydrogen-bonded Turntrans-82.4-10.5172.971.3-41.1000113.3F294 L327 L330 Q332 K333 V334 G347F294-N349 WeakPolarHBondContact CZ-O 3.43Å; L327-N349 PolarHBondContact O-ND2 2.95Å; L330-N349 PolarHBondContact O-ND2 3.37Å; Q332-N349 PolarHBondContact O-ND2 3.13Å; K333-N349 CarbonylContact C-O 3.59Å; K333-N349 VanDerWaalsContact CA-O 3.29Å; K333-N349 WeakPolarHBondContact CA-O 3.46Å; K333-N349 HydrophobicContact CD-CB 4.15Å; V334-N349 PolarHBondContact N-O 3.4Å; G347-N349 PolarHBondContact O-N 3.38Å; G347-N349 VanDerWaalsContact O-N 3.09Å
350T98.6Very high96.5Very high9 Ų956.6 Ų56.66%0.05530%0.297CS..EExtended strand (participates in β ladder)trans-110.1137.4-175.8-570000111.4L327 V334 W336 L346 G347 S348 L352L327-T350 HydrophobicContact CD1-CG2 4.43Å; V334-T350 HydrophobicContact CB-CG2 3.96Å; V334-T350 HydrophobicContact CG1-CG2 4.15Å; V334-T350 CarbonylContact O-C 3.1Å; V334-T350 WeakPolarHBondContact O-CA 3.41Å; W336-T350 HydrophobicContact CB-CG2 4.16Å; W336-T350 HydrophobicContact CE3-CG2 4.16Å; L346-T350 HydrophobicContact CD1-CG2 3.68Å; G347-T350 PolarHBondContact O-N 2.9Å; S348-T350 VanDerWaalsContact C-N 3.35Å; T350-L352 HydrophobicContact CG2-CD2 4.39Å
351K98.1Very high96.8Very high80 Ų8055.7 Ų55.735%0.34829%0.288SS..EExtended strand (participates in β ladder)trans-122.1133.3170.5-80.1-172.5-178.9175.60111.1F294 V334 W336 Y353F294-K351 HydrophobicContact CB-CD 4.27Å; F294-K351 HydrophobicContact CD1-CB 4.44Å; F294-K351 HydrophobicContact CD1-CD 3.86Å; F294-K351 HydrophobicContact CD1-CG 4.35Å; F294-K351 HydrophobicContact CD2-CD 3.5Å; F294-K351 VanDerWaalsContact CD2-CD 3.5Å; F294-K351 HydrophobicContact CD2-CG 4.11Å; F294-K351 VanDerWaalsContact CD2-NZ 3.33Å; F294-K351 HydrophobicContact CE1-CB 3.9Å; F294-K351 HydrophobicContact CE1-CD 3.96Å; F294-K351 HydrophobicContact CE1-CG 3.93Å; F294-K351 HydrophobicContact CE2-CB 4.49Å; F294-K351 HydrophobicContact CE2-CD 3.59Å; F294-K351 VanDerWaalsContact CE2-CE 3.47Å; F294-K351 HydrophobicContact CE2-CG 3.65Å; F294-K351 HydrophobicContact CG-CD 3.6Å; F294-K351 HydrophobicContact CG-CG 4.41Å; F294-K351 HydrophobicContact CZ-CB 3.91Å; F294-K351 HydrophobicContact CZ-CD 3.81Å; F294-K351 HydrophobicContact CZ-CG 3.54Å; V334-K351 PolarHBondContact O-N 2.72Å; W336-K351 PolarHBondContact N-O 3.28Å; K351-Y353 HydrophobicContact CB-CD2 4.49Å; K351-Y353 HydrophobicContact CB-CE2 3.71Å
352L97.9Very high96.9Very high45 Ų4549.9 Ų49.924%0.23626%0.262CS..EExtended strand (participates in β ladder)trans-89.2143.6177.1-52.7-177.9000111W336 Y338 I342 L346 T350W336-L352 HydrophobicContact CB-CD2 3.99Å; W336-L352 HydrophobicContact CD2-CD2 3.84Å; W336-L352 HydrophobicContact CE3-CD2 3.52Å; W336-L352 HydrophobicContact CG-CD2 4.08Å; W336-L352 HydrophobicContact CZ3-CD2 4.3Å; W336-L352 CarbonylContact O-C 3.6Å; W336-L352 VanDerWaalsContact O-CA 3.28Å; W336-L352 WeakPolarHBondContact O-CA 3.36Å; Y338-L352 HydrophobicContact CD1-CD1 4.16Å; I342-L352 HydrophobicContact CB-CD1 4.45Å; I342-L352 HydrophobicContact CG1-CD1 4.14Å; I342-L352 HydrophobicContact CG2-CD1 4.22Å; L346-L352 HydrophobicContact CD1-CD2 4Å; L346-L352 HydrophobicContact CD1-CG 4.36Å; L346-L352 HydrophobicContact CD2-CD1 4.03Å; L346-L352 HydrophobicContact CD2-CG 4.05Å; T350-L352 HydrophobicContact CG2-CD2 4.39Å
353Y95.9Very high97Very high38 Ų3845.7 Ų45.715%0.14925%0.247CC..EExtended strand (participates in β ladder)trans-139140.2176.6-66.2-92.5000110.3I291 L335 W336 R337 Y338 K351 M356I291-Y353 HydrophobicContact CD1-CE1 4.16Å; I291-Y353 HydrophobicContact CG1-CE1 4.02Å; L335-Y353 HydrophobicContact CB-CD2 4.43Å; L335-Y353 HydrophobicContact CB-CE2 4.15Å; L335-Y353 HydrophobicContact CD2-CE2 3.83Å; L335-Y353 HydrophobicContact CG-CE2 4.08Å; W336-Y353 PolarHBondContact O-N 3.18Å; R337-Y353 CarbonylContact C-O 3.45Å; R337-Y353 WeakPolarHBondContact CA-O 3.15Å; R337-Y353 WeakPolarHBondContact CG-O 3.24Å; Y338-Y353 PolarHBondContact N-O 2.96Å; K351-Y353 HydrophobicContact CB-CD2 4.49Å; K351-Y353 HydrophobicContact CB-CE2 3.71Å; Y353-M356 HydrophobicContact CG-CB 4.48Å
354D92.1Very high97Very high114 Ų11446.7 Ų46.761%0.6125%0.251SS*.SBendtrans-70.3-38.7169.4-64.9-44000111.4R337 S339R337-D354 WeakPolarHBondContact CG-O 3.49Å; R337-D354 PolarHBondContact NE-O 3.11Å; S339-D354 WeakPolarHBondContact CB-OD1 3.48Å; S339-D354 WeakPolarHBondContact OG-CA 3.38Å; S339-D354 PolarHBondContact OG-OD1 3.45Å
355W91.9Very high97Very high168 Ų16847 Ų4764%0.63626%0.26SS*.SBendtrans-144.2143.2175.4-167.1-101.4000110.5
356M94.1Very high97Very high5 Ų546.5 Ų46.53%0.02525%0.252CS..  trans-138.5149.6179.660.1179.4178.500111V305 F306 L335 R337 Y353 Q358 L361V305-M356 HydrophobicContact CG1-CE 3.6Å; V305-M356 HydrophobicContact CG1-SD 4.22Å; F306-M356 WeakPolarHBondContact O-CE 3.21Å; L335-M356 HydrophobicContact CB-SD 4.27Å; R337-M356 HydrophobicContact CB-CE 3.7Å; R337-M356 HydrophobicContact CB-CG 4.28Å; R337-M356 HydrophobicContact CB-SD 4.21Å; Y353-M356 HydrophobicContact CG-CB 4.48Å; M356-Q358 PolarHBondContact O-N 3.44Å; M356-L361 HydrophobicContact CB-CD1 3.96Å; M356-L361 HydrophobicContact CG-CD1 4.15Å; M356-L361 HydrophobicContact SD-CD1 3.89Å
357P95.5Very high97Very high32 Ų3244.2 Ų44.221%0.20824%0.241CC..  trans-73.174.4176.532.2-35.7000110.2L287 I291 N359 D360 L361L287-P357 HydrophobicContact CD2-CG 3.85Å; I291-P357 HydrophobicContact CD1-CG 4.13Å; P357-N359 PolarHBondContact O-N 3.45Å; P357-D360 HydrophobicContact CB-CB 4.16Å; P357-D360 PolarHBondContact O-N 2.96Å; P357-D360 VanDerWaalsContact O-N 3.1Å; P357-L361 HydrophobicContact CG-CD1 4.5Å; P357-L361 HydrophobicContact CG-CG 4.45Å; P357-L361 PolarHBondContact O-N 2.99Å
358Q97.1Very high97.1Very high37 Ų3747.5 Ų47.517%0.17325%0.251CS..Hα-helixtrans-55.9-49.7-170-175.8176.8-76.200112.5V305 S307 M356 D360 L361 L362 F370 E381V305-Q358 HydrophobicContact CG1-CG 4.43Å; S307-Q358 PolarHBondContact OG-OE1 3.3Å; M356-Q358 PolarHBondContact O-N 3.44Å; Q358-D360 VanDerWaalsContact C-N 3.28Å; Q358-D360 PolarHBondContact O-N 3.08Å; Q358-L361 PolarHBondContact O-N 3.3Å; Q358-L362 HydrophobicContact CG-CD1 3.94Å; Q358-L362 HydrophobicContact CG-CG 4.32Å; Q358-L362 WeakPolarHBondContact O-CB 3.48Å; Q358-L362 VanDerWaalsContact O-CG 3.29Å; Q358-L362 WeakPolarHBondContact O-CG 3.28Å; Q358-L362 PolarHBondContact O-N 2.86Å; Q358-F370 HydrophobicContact CG-CZ 4.42Å; Q358-E381 PolarHBondContact NE2-OE2 3.43Å
359N96.6Very high97.2Very high7 Ų741.8 Ų41.84%0.03721%0.211CC..Hα-helixtrans-53.1-45.8176.1176.583000112.5K282 P357 L362 G363 H385K282-N359 VanDerWaalsContact CG-ND2 3.34Å; K282-N359 WeakPolarHBondContact CG-ND2 3.37Å; K282-N359 PolarHBondContact O-ND2 3.06Å; K282-N359 PolarHBondContact O-OD1 3.4Å; P357-N359 PolarHBondContact O-N 3.45Å; N359-L362 PolarHBondContact O-N 2.85Å; N359-G363 PolarHBondContact O-N 3.33Å; N359-H385 PolarHBondContact O-NE2 2.94Å; N359-H385 VanDerWaalsContact O-NE2 3.17Å; N359-H385 PolarHBondContact OD1-NE2 2.88Å
360D98Very high97.2Very high23 Ų2341.2 Ų41.212%0.12321%0.208CC..Hα-helixtrans-73.5-35.4-175.1-54.5-37.8000111.3A284 K285 L287 P357 Q358 G363 H364A284-D360 WeakPolarHBondContact CA-OD1 3.45Å; A284-D360 HydrophobicContact CB-CB 4.49Å; K285-D360 PolarHBondContact N-OD1 3.15Å; L287-D360 HydrophobicContact CD2-CB 3.67Å; P357-D360 HydrophobicContact CB-CB 4.16Å; P357-D360 PolarHBondContact O-N 2.96Å; P357-D360 VanDerWaalsContact O-N 3.1Å; Q358-D360 VanDerWaalsContact C-N 3.28Å; Q358-D360 PolarHBondContact O-N 3.08Å; D360-G363 PolarHBondContact O-N 2.95Å; D360-H364 PolarHBondContact O-N 3.2Å
361L98.6Very high97.2Very high0 Ų040.8 Ų40.80%021%0.205CC..Hα-helixtrans-65.3-43.4171.4-74.3166.6000111.4L287 I291 V295 I303 V305 L335 M356 P357 Q358 G363 H364 T367L287-L361 HydrophobicContact CD1-CD2 3.7Å; L287-L361 HydrophobicContact CD2-CD2 4.04Å; L287-L361 HydrophobicContact CD2-CG 4.04Å; I291-L361 HydrophobicContact CG2-CD2 3.98Å; V295-L361 HydrophobicContact CG2-CD2 4.06Å; I303-L361 HydrophobicContact CD1-CD2 4.17Å; V305-L361 HydrophobicContact CG2-CB 3.74Å; L335-L361 HydrophobicContact CD1-CD2 4.45Å; L335-L361 HydrophobicContact CD2-CD1 3.97Å; L335-L361 HydrophobicContact CD2-CD2 3.7Å; M356-L361 HydrophobicContact CB-CD1 3.96Å; M356-L361 HydrophobicContact CG-CD1 4.15Å; M356-L361 HydrophobicContact SD-CD1 3.89Å; P357-L361 HydrophobicContact CG-CD1 4.5Å; P357-L361 HydrophobicContact CG-CG 4.45Å; P357-L361 PolarHBondContact O-N 2.99Å; Q358-L361 PolarHBondContact O-N 3.3Å; L361-G363 VanDerWaalsContact C-N 3.31Å; L361-G363 PolarHBondContact O-N 2.6Å; L361-H364 VanDerWaalsContact O-CB 3.29Å; L361-H364 WeakPolarHBondContact O-CB 3.43Å; L361-H364 PolarHBondContact O-N 2.98Å; L361-H364 VanDerWaalsContact O-N 3.11Å; L361-T367 PolarHBondContact O-OG1 3.43Å
362L98.6Very high97.2Very high1 Ų137 Ų371%0.00519%0.189CC..Hα-helixtrans-63.8-37.1178-70.3175.6000111.9V305 Q358 N359 H364 T367 F370 E381 H385 I387V305-L362 HydrophobicContact CB-CD2 4.14Å; V305-L362 HydrophobicContact CG1-CD2 4.43Å; V305-L362 HydrophobicContact CG2-CD2 4.21Å; Q358-L362 HydrophobicContact CG-CD1 3.94Å; Q358-L362 HydrophobicContact CG-CG 4.32Å; Q358-L362 WeakPolarHBondContact O-CB 3.48Å; Q358-L362 VanDerWaalsContact O-CG 3.29Å; Q358-L362 WeakPolarHBondContact O-CG 3.28Å; Q358-L362 PolarHBondContact O-N 2.86Å; N359-L362 PolarHBondContact O-N 2.85Å; L362-H364 VanDerWaalsContact C-N 3.27Å; L362-H364 PolarHBondContact O-N 3.18Å; L362-T367 HydrophobicContact CD2-CG2 4.4Å; L362-F370 HydrophobicContact CD1-CD1 4.31Å; L362-F370 HydrophobicContact CD1-CE1 4.29Å; L362-F370 HydrophobicContact CD2-CB 3.72Å; L362-F370 HydrophobicContact CD2-CD1 4.19Å; L362-F370 HydrophobicContact CD2-CD2 3.97Å; L362-F370 HydrophobicContact CD2-CG 3.72Å; L362-E381 HydrophobicContact CD1-CB 3.65Å; L362-H385 HydrophobicContact CB-CB 4.29Å; L362-H385 WeakPolarHBondContact O-CB 3.29Å; L362-I387 HydrophobicContact CB-CG1 4.45Å; L362-I387 HydrophobicContact CD2-CB 4.39Å; L362-I387 HydrophobicContact CD2-CG1 4.34Å; L362-I387 HydrophobicContact CD2-CG2 4.19Å; L362-I387 WeakPolarHBondContact O-CD1 3.25Å; L362-I387 VanDerWaalsContact O-CG1 3.29Å; L362-I387 WeakPolarHBondContact O-CG1 3.24Å
363G98.3Very high97.2Very high26 Ų2635.9 Ų35.927%0.26818%0.183SC..THydrogen-bonded Turntrans-80.61.6174.200000115.4N359 D360 L361 H385N359-G363 PolarHBondContact O-N 3.33Å; D360-G363 PolarHBondContact O-N 2.95Å; L361-G363 VanDerWaalsContact C-N 3.31Å; L361-G363 PolarHBondContact O-N 2.6Å; G363-H385 VanDerWaalsContact CA-CG 3.42Å; G363-H385 WeakPolarHBondContact CA-ND1 3.46Å
364H98.5Very high97.3Very high26 Ų2634.1 Ų34.112%0.1218%0.175CC..SBendtrans-75.8134.9178.4-171.2-85.9000111.3E292 V295 D360 L361 L362 K366 T367E292-H364 IonicContact OE1-NE2 3.43Å; E292-H364 IonicContact OE2-CD2 2.6Å; E292-H364 IonicContact OE2-NE2 3.25Å; V295-H364 WeakPolarHBondContact CG1-CE1 3.36Å; V295-H364 WeakPolarHBondContact CG1-ND1 3.41Å; D360-H364 PolarHBondContact O-N 3.2Å; L361-H364 VanDerWaalsContact O-CB 3.29Å; L361-H364 WeakPolarHBondContact O-CB 3.43Å; L361-H364 PolarHBondContact O-N 2.98Å; L361-H364 VanDerWaalsContact O-N 3.11Å; L362-H364 VanDerWaalsContact C-N 3.27Å; L362-H364 PolarHBondContact O-N 3.18Å; H364-K366 PolarHBondContact ND1-N 3.02Å; H364-K366 VanDerWaalsContact ND1-N 3.13Å; H364-K366 PolarHBondContact O-N 2.82Å; H364-T367 WeakPolarHBondContact O-CB 3.23Å; H364-T367 PolarHBondContact O-N 2.86Å; H364-T367 PolarHBondContact O-OG1 3.24Å
365P97.6Very high97.5Very high119 Ų11929 Ų2977%0.77315%0.15SC*.THydrogen-bonded Turntrans-59-23.1-175.4-27.134.7000115.9T367P365-T367 VanDerWaalsContact C-N 3.34Å
366K98.4Very high97.7Very high44 Ų4421.7 Ų21.719%0.19112%0.124CC..THydrogen-bonded Turntrans-81.9-7.4177.2-69-172.5172.9-71.10114V295 G299 G302 I303 H364 K368V295-K366 HydrophobicContact CG1-CB 4.22Å; V295-K366 HydrophobicContact CG1-CD 4.22Å; G299-K366 PolarHBondContact O-NZ 2.94Å; G302-K366 CarbonylContact C-O 3.58Å; G302-K366 VanDerWaalsContact CA-O 3.28Å; G302-K366 WeakPolarHBondContact CA-O 3.34Å; I303-K366 PolarHBondContact N-O 3.05Å; H364-K366 PolarHBondContact ND1-N 3.02Å; H364-K366 VanDerWaalsContact ND1-N 3.13Å; H364-K366 PolarHBondContact O-N 2.82Å; K366-K368 PolarHBondContact O-N 3.44Å
367T98.8Very high97.8Very high7 Ų722.9 Ų22.94%0.04313%0.131CC..EExtended strand (participates in β ladder)trans-73.4124.8-177.6-60.70000111.2I303 V305 L361 L362 H364 P365 I387I303-T367 WeakPolarHBondContact CD1-OG1 3.36Å; I303-T367 WeakPolarHBondContact CG1-OG1 3.42Å; V305-T367 HydrophobicContact CG2-CG2 4.09Å; L361-T367 PolarHBondContact O-OG1 3.43Å; L362-T367 HydrophobicContact CD2-CG2 4.4Å; H364-T367 WeakPolarHBondContact O-CB 3.23Å; H364-T367 PolarHBondContact O-N 2.86Å; H364-T367 PolarHBondContact O-OG1 3.24Å; P365-T367 VanDerWaalsContact C-N 3.34Å; T367-I387 HydrophobicContact CG2-CD1 3.94Å; T367-I387 HydrophobicContact CG2-CG1 4.12Å; T367-I387 HydrophobicContact CG2-CG2 3.92Å
368K98.7Very high97.8Very high83 Ų8321.6 Ų21.636%0.36112%0.123SC..EExtended strand (participates in β ladder)trans-105.2-37.2-176.6-58.7-56.3-174.1177.70112.9A301 I303 K366 P388 I432A301-K368 WeakPolarHBondContact O-CG 3.26Å; I303-K368 PolarHBondContact O-N 2.73Å; K366-K368 PolarHBondContact O-N 3.44Å; K368-P388 WeakPolarHBondContact O-CD 3.44Å; K368-P388 WeakPolarHBondContact O-CG 3.15Å; K368-I432 HydrophobicContact CB-CD1 4.15Å; K368-I432 HydrophobicContact CB-CG1 4.03Å; K368-I432 HydrophobicContact CB-CG2 4.31Å
369A98.8Very high97.9Very high0 Ų019.8 Ų19.80%011%0.114CC..EExtended strand (participates in β ladder)trans-152.3157.8-178.700000111.4V305 P388 V431 I432V305-A369 PolarHBondContact N-O 2.88Å; A369-P388 WeakPolarHBondContact CA-O 3.33Å; A369-V431 HydrophobicContact CB-CG2 3.89Å; A369-I432 HydrophobicContact CB-CD1 4.2Å; A369-I432 HydrophobicContact CB-CG1 3.81Å
370F98.9Very high98Very high1 Ų119.6 Ų19.60%0.00411%0.113CC..EExtended strand (participates in β ladder)trans-119116.4173.1-179.7-145.8000110.4V305 Q358 L362 T372 A382 I387 P388 M389 V390V305-F370 HydrophobicContact CB-CD2 3.99Å; V305-F370 HydrophobicContact CG1-CD2 3.98Å; V305-F370 HydrophobicContact CG1-CE2 4.05Å; V305-F370 CarbonylContact O-C 3.57Å; V305-F370 WeakPolarHBondContact O-CA 3.45Å; V305-F370 WeakPolarHBondContact O-CD2 3.17Å; Q358-F370 HydrophobicContact CG-CZ 4.42Å; L362-F370 HydrophobicContact CD1-CD1 4.31Å; L362-F370 HydrophobicContact CD1-CE1 4.29Å; L362-F370 HydrophobicContact CD2-CB 3.72Å; L362-F370 HydrophobicContact CD2-CD1 4.19Å; L362-F370 HydrophobicContact CD2-CD2 3.97Å; L362-F370 HydrophobicContact CD2-CG 3.72Å; F370-T372 HydrophobicContact CD1-CG2 4.07Å; F370-T372 VanDerWaalsContact CE1-CB 3.41Å; F370-T372 HydrophobicContact CE1-CG2 4.14Å; F370-T372 WeakPolarHBondContact CE1-OG1 3.19Å; F370-A382 HydrophobicContact CD1-CB 3.92Å; F370-I387 HydrophobicContact CB-CG2 3.87Å; F370-P388 PolarHBondContact N-O 3.33Å; F370-M389 HydrophobicContact CB-CG 4.11Å; F370-M389 HydrophobicContact CD1-CG 4.07Å; F370-M389 HydrophobicContact CD1-SD 4.3Å; F370-M389 CarbonylContact O-C 3.58Å; F370-M389 WeakPolarHBondContact O-CA 3.35Å; F370-V390 PolarHBondContact O-N 3.43Å
371I98.9Very high98Very high0 Ų019.8 Ų19.80%011%0.113CC..EExtended strand (participates in β ladder)trans-86.8120.9168.5-53.1171.6000107.1I304 V305 F306 S307 L327 V390 I392 I428I304-I371 HydrophobicContact CG2-CD1 3.7Å; I304-I371 HydrophobicContact CG2-CG1 3.77Å; V305-I371 PolarHBondContact O-N 2.64Å; F306-I371 WeakPolarHBondContact CA-O 3.46Å; F306-I371 HydrophobicContact CB-CB 3.99Å; F306-I371 HydrophobicContact CB-CD1 4.31Å; F306-I371 HydrophobicContact CD1-CD1 4.49Å; F306-I371 HydrophobicContact CD2-CB 3.51Å; F306-I371 HydrophobicContact CD2-CG2 3.35Å; F306-I371 WeakPolarHBondContact CD2-O 3.09Å; F306-I371 HydrophobicContact CE2-CB 4.21Å; F306-I371 HydrophobicContact CE2-CG2 3.52Å; F306-I371 HydrophobicContact CG-CB 3.83Å; F306-I371 HydrophobicContact CG-CD1 4.26Å; F306-I371 HydrophobicContact CG-CG2 3.99Å; F306-I371 HydrophobicContact CZ-CG2 4.24Å; S307-I371 PolarHBondContact N-O 2.98Å; L327-I371 HydrophobicContact CD2-CD1 3.72Å; I371-V390 WeakPolarHBondContact CA-O 3.45Å; I371-V390 HydrophobicContact CG1-CB 4.41Å; I371-I392 HydrophobicContact CG2-CD1 3.73Å; I371-I392 HydrophobicContact CG2-CG1 4.14Å; I371-I428 HydrophobicContact CD1-CD1 3.54Å; I371-I428 HydrophobicContact CD1-CG1 4.01Å; I371-I428 HydrophobicContact CG1-CD1 4.36Å; I371-I428 HydrophobicContact CG1-CG1 4.31Å
372T98.6Very high98Very high0 Ų019.8 Ų19.80%011%0.113CC..EExtended strand (participates in β ladder)trans-139.6148.9-168.4-177.20000112.3S307 F370 G374 M389 V390 G391 I392 M402S307-T372 WeakPolarHBondContact O-CA 3.34Å; F370-T372 HydrophobicContact CD1-CG2 4.07Å; F370-T372 VanDerWaalsContact CE1-CB 3.41Å; F370-T372 HydrophobicContact CE1-CG2 4.14Å; F370-T372 WeakPolarHBondContact CE1-OG1 3.19Å; T372-G374 PolarHBondContact O-N 3Å; T372-G374 PolarHBondContact OG1-N 3.44Å; T372-M389 HydrophobicContact CG2-CB 4.14Å; T372-M389 HydrophobicContact CG2-CG 4.11Å; T372-M389 HydrophobicContact CG2-SD 4.01Å; T372-V390 PolarHBondContact N-O 2.98Å; T372-G391 CarbonylContact O-C 3.42Å; T372-G391 VanDerWaalsContact O-CA 3.3Å; T372-G391 WeakPolarHBondContact O-CA 3.13Å; T372-I392 PolarHBondContact O-N 3.29Å; T372-M402 HydrophobicContact CG2-SD 4.38Å
373H97.6Very high98Very high23 Ų2319.7 Ų19.711%0.10611%0.113CC..  trans-66.6-9.416469.5-40.1000114.5S307 L308 G375 I392 P393 M394 Q398S307-H373 PolarHBondContact O-N 3.46Å; L308-H373 HydrophobicContact CB-CB 4.3Å; L308-H373 HydrophobicContact CD2-CB 3.89Å; L308-H373 PolarHBondContact O-CD2 2.97Å; H373-G375 PolarHBondContact CE1-N 2.82Å; H373-I392 VanDerWaalsContact CA-O 3.3Å; H373-I392 WeakPolarHBondContact CA-O 3.28Å; H373-P393 WeakPolarHBondContact O-CA 3.18Å; H373-M394 HydrophobicContact CB-CG 4.02Å; H373-Q398 VanDerWaalsContact CD2-CD 3.42Å; H373-Q398 PolarHBondContact CD2-NE2 3.43Å; H373-Q398 VanDerWaalsContact CD2-NE2 3.33Å; H373-Q398 WeakPolarHBondContact O-CB 3.4Å; H373-Q398 VanDerWaalsContact O-CG 3.25Å; H373-Q398 WeakPolarHBondContact O-CG 3.28Å; H373-Q398 PolarHBondContact O-OE1 3.35Å
374G97.6Very high98Very high0 Ų020.3 Ų20.30%011%0.107CC..  trans80.516.6-179.300000114.9T372 I379 N401 M402T372-G374 PolarHBondContact O-N 3Å; T372-G374 PolarHBondContact OG1-N 3.44Å; G374-I379 VanDerWaalsContact O-CD1 3.26Å; G374-I379 WeakPolarHBondContact O-CD1 3.37Å; G374-N401 WeakPolarHBondContact O-CB 3.29Å; G374-N401 PolarHBondContact O-ND2 2.91Å; G374-M402 WeakPolarHBondContact CA-SD 3.25Å
375G96.8Very high98Very high8 Ų820.7 Ų20.78%0.08211%0.109CC..  trans-64.3138.7169.700000111.5H373 N377 G378 I379H373-G375 PolarHBondContact CE1-N 2.82Å; G375-N377 VanDerWaalsContact C-N 3.26Å; G375-N377 PolarHBondContact O-N 3.35Å; G375-N377 VanDerWaalsContact O-N 3.1Å; G375-G378 PolarHBondContact O-N 3.29Å; G375-I379 PolarHBondContact O-N 2.91Å; G375-I379 VanDerWaalsContact O-N 3.11Å
376T96.1Very high98.1Very high13 Ų1315 Ų158%0.087%0.072CC..Hα-helixtrans-50.2-41.5-173-64.60000113.2R172 F263 G378 I379 Y380 D397 N401R172-T376 PolarHBondContact NE-OG1 3.34Å; F263-T376 HydrophobicContact CE1-CG2 4.3Å; T376-G378 PolarHBondContact O-N 3.3Å; T376-I379 PolarHBondContact O-N 2.84Å; T376-Y380 HydrophobicContact CG2-CD2 3.65Å; T376-Y380 HydrophobicContact CG2-CE2 3.57Å; T376-Y380 WeakPolarHBondContact O-CD2 3.16Å; T376-Y380 PolarHBondContact O-N 3.39Å; T376-D397 PolarHBondContact OG1-OD2 3.49Å; T376-N401 PolarHBondContact OG1-ND2 3.39Å
377N95.1Very high98.1Very high31 Ų3113.1 Ų13.117%0.1666%0.064CC..Hα-helixtrans-62.1-45.4179.9-70.7-8.7000112.5S32 N36 H280 G375 I379 Y380 E381S32-N377 PolarHBondContact O-ND2 3.29Å; N36-N377 PolarHBondContact ND2-OD1 3.33Å; H280-N377 VanDerWaalsContact CE1-CA 3.47Å; H280-N377 WeakPolarHBondContact CE1-CA 3.25Å; H280-N377 PolarHBondContact CE1-O 2.88Å; H280-N377 WeakPolarHBondContact NE2-CA 3.33Å; H280-N377 PolarHBondContact NE2-O 3.15Å; G375-N377 VanDerWaalsContact C-N 3.26Å; G375-N377 PolarHBondContact O-N 3.35Å; G375-N377 VanDerWaalsContact O-N 3.1Å; N377-I379 VanDerWaalsContact C-N 3.33Å; N377-Y380 PolarHBondContact O-N 3.41Å; N377-E381 WeakPolarHBondContact O-CG 3.44Å; N377-E381 PolarHBondContact O-N 3.39Å; N377-E381 VanDerWaalsContact O-N 3.1Å
378G96.8Very high98.1Very high4 Ų412.9 Ų12.94%0.0416%0.063CC..Hα-helixtrans-67.8-34.7178.600000112.3G375 T376 E381 A382G375-G378 PolarHBondContact O-N 3.29Å; T376-G378 PolarHBondContact O-N 3.3Å; G378-E381 PolarHBondContact O-N 3.08Å; G378-A382 WeakPolarHBondContact O-CB 3.42Å; G378-A382 PolarHBondContact O-N 3.4Å
379I98.3Very high98.1Very high0 Ų09 Ų90%05%0.046CC..Hα-helixtrans-62-47.1174.1-72.7173.1000110.8F263 G374 G375 T376 N377 E381 A382 I383 M389 N401 M402 M405F263-I379 HydrophobicContact CD2-CG2 3.7Å; F263-I379 HydrophobicContact CE2-CD1 4Å; F263-I379 HydrophobicContact CE2-CG2 3.95Å; F263-I379 HydrophobicContact CG-CG2 4.26Å; F263-I379 HydrophobicContact CZ-CD1 4.34Å; G374-I379 VanDerWaalsContact O-CD1 3.26Å; G374-I379 WeakPolarHBondContact O-CD1 3.37Å; G375-I379 PolarHBondContact O-N 2.91Å; G375-I379 VanDerWaalsContact O-N 3.11Å; T376-I379 PolarHBondContact O-N 2.84Å; N377-I379 VanDerWaalsContact C-N 3.33Å; I379-E381 PolarHBondContact O-N 3.43Å; I379-A382 WeakPolarHBondContact O-CB 3.39Å; I379-A382 PolarHBondContact O-N 2.89Å; I379-I383 HydrophobicContact CG2-CD1 3.78Å; I379-I383 HydrophobicContact CG2-CG1 4.35Å; I379-I383 WeakPolarHBondContact O-CG1 3.12Å; I379-I383 PolarHBondContact O-N 3.3Å; I379-M389 HydrophobicContact CG1-SD 4.11Å; I379-M389 HydrophobicContact CG2-CE 4.5Å; I379-N401 HydrophobicContact CD1-CB 3.58Å; I379-M402 HydrophobicContact CD1-SD 4.44Å; I379-M405 HydrophobicContact CD1-CG 4.08Å; I379-M405 HydrophobicContact CG1-CG 4.39Å; I379-M405 HydrophobicContact CG2-CG 3.99Å; I379-M405 HydrophobicContact CG2-SD 3.69Å
380Y98.2Very high98.1Very high2 Ų29 Ų91%0.0085%0.046CC..Hα-helixtrans-65-37.7177.9-86-65.6000113R258 T259 F260 F263 C281 T376 N377 A382 I383 Y384 H448R258-Y380 WeakPolarHBondContact O-CE2 3.48Å; T259-Y380 VanDerWaalsContact C-OH 3.31Å; T259-Y380 WeakPolarHBondContact CA-OH 3.3Å; F260-Y380 PolarHBondContact N-OH 2.95Å; F263-Y380 HydrophobicContact CB-CE1 4.02Å; F263-Y380 WeakPolarHBondContact CB-OH 3.25Å; F263-Y380 AromaticContact CD1-CE2 3.97Å; F263-Y380 HydrophobicContact CD1-CE2 3.97Å; F263-Y380 AromaticContact CD1-CZ 3.9Å; F263-Y380 WeakPolarHBondContact CD1-OH 3.48Å; C281-Y380 VanDerWaalsContact SG-C 3.52Å; T376-Y380 HydrophobicContact CG2-CD2 3.65Å; T376-Y380 HydrophobicContact CG2-CE2 3.57Å; T376-Y380 WeakPolarHBondContact O-CD2 3.16Å; T376-Y380 PolarHBondContact O-N 3.39Å; N377-Y380 PolarHBondContact O-N 3.41Å; Y380-A382 VanDerWaalsContact C-N 3.3Å; Y380-A382 PolarHBondContact O-N 3.27Å; Y380-I383 PolarHBondContact O-N 3.16Å; Y380-Y384 WeakPolarHBondContact O-CB 3.28Å; Y380-Y384 PolarHBondContact O-N 3.46Å; Y380-H448 AromaticContact CD1-CE1 3.86Å; Y380-H448 AromaticContact CD1-ND1 3.95Å
381E98.3Very high98Very high27 Ų278.9 Ų8.913%0.1265%0.045CC..Hα-helixtrans-62.4-40.1173.2-68.9174.2171.700111.3H280 Q358 L362 N377 G378 I379 Y384 H385H280-E381 IonicContact CD2-OE1 3.97Å; Q358-E381 PolarHBondContact NE2-OE2 3.43Å; L362-E381 HydrophobicContact CD1-CB 3.65Å; N377-E381 WeakPolarHBondContact O-CG 3.44Å; N377-E381 PolarHBondContact O-N 3.39Å; N377-E381 VanDerWaalsContact O-N 3.1Å; G378-E381 PolarHBondContact O-N 3.08Å; I379-E381 PolarHBondContact O-N 3.43Å; E381-Y384 PolarHBondContact O-N 2.93Å; E381-H385 PolarHBondContact O-CD2 3.36Å; E381-H385 PolarHBondContact O-N 2.84Å; E381-H385 VanDerWaalsContact O-N 3.08Å
382A98.7Very high98Very high0 Ų09 Ų90%05%0.046CC..Hα-helixtrans-66.2-43.1175.900000112.3F370 G378 I379 Y380 G386 I387 M389F370-A382 HydrophobicContact CD1-CB 3.92Å; G378-A382 WeakPolarHBondContact O-CB 3.42Å; G378-A382 PolarHBondContact O-N 3.4Å; I379-A382 WeakPolarHBondContact O-CB 3.39Å; I379-A382 PolarHBondContact O-N 2.89Å; Y380-A382 VanDerWaalsContact C-N 3.3Å; Y380-A382 PolarHBondContact O-N 3.27Å; A382-G386 CarbonylContact O-C 3.58Å; A382-G386 WeakPolarHBondContact O-CA 3.25Å; A382-G386 PolarHBondContact O-N 3.3Å; A382-I387 PolarHBondContact O-N 3.5Å; A382-M389 HydrophobicContact CB-CE 4.05Å; A382-M389 HydrophobicContact CB-CG 3.94Å; A382-M389 HydrophobicContact CB-SD 3.52Å; A382-M389 VanDerWaalsContact CB-SD 3.52Å
383I98.8Very high98Very high0 Ų010 Ų100%05%0.053CC..Hα-helixtrans-62.1-48.4173.4-69.8171000110.2D262 F263 I379 Y380 H385 G386 M405 L444 S445 H448D262-I383 HydrophobicContact CB-CG2 4.27Å; F263-I383 HydrophobicContact CB-CD1 3.9Å; I379-I383 HydrophobicContact CG2-CD1 3.78Å; I379-I383 HydrophobicContact CG2-CG1 4.35Å; I379-I383 WeakPolarHBondContact O-CG1 3.12Å; I379-I383 PolarHBondContact O-N 3.3Å; Y380-I383 PolarHBondContact O-N 3.16Å; I383-H385 VanDerWaalsContact C-N 3.28Å; I383-H385 PolarHBondContact O-N 2.91Å; I383-G386 PolarHBondContact O-N 2.86Å; I383-M405 HydrophobicContact CD1-CE 4.03Å; I383-M405 HydrophobicContact CD1-SD 4.01Å; I383-M405 HydrophobicContact CG1-CE 3.96Å; I383-L444 HydrophobicContact CG2-CB 3.99Å; I383-S445 VanDerWaalsContact O-CA 3.22Å; I383-S445 WeakPolarHBondContact O-CA 3.42Å; I383-S445 WeakPolarHBondContact O-CB 3.45Å; I383-S445 PolarHBondContact O-OG 3.33Å; I383-S445 VanDerWaalsContact O-OG 3.13Å; I383-H448 HydrophobicContact CG2-CB 3.88Å
384Y98.5Very high97.8Very high39 Ų399.3 Ų9.315%0.1535%0.049CC..Hα-helixtrans-54.1-45.1-179.1-175.2-81000111.4C281 K282 P283 Y380 E381 S445 H448 H449C281-Y384 HydrophobicContact CB-CD2 3.36Å; C281-Y384 HydrophobicContact CB-CE2 3.88Å; C281-Y384 HydrophobicContact CB-CG 3.79Å; K282-Y384 WeakPolarHBondContact O-CE1 3.3Å; P283-Y384 VanDerWaalsContact CD-OH 3.3Å; P283-Y384 WeakPolarHBondContact CD-OH 3.32Å; Y380-Y384 WeakPolarHBondContact O-CB 3.28Å; Y380-Y384 PolarHBondContact O-N 3.46Å; E381-Y384 PolarHBondContact O-N 2.93Å; Y384-S445 PolarHBondContact O-OG 2.89Å; Y384-H448 AromaticContact CD2-CD2 3.51Å; Y384-H448 AromaticContact CD2-NE2 3.49Å; Y384-H448 WeakPolarHBondContact CD2-NE2 3.47Å; Y384-H449 AromaticContact CD1-CE1 3.97Å; Y384-H449 AromaticContact CD2-CE1 3.58Å; Y384-H449 AromaticContact CE1-CE1 3.76Å; Y384-H449 AromaticContact CE2-CE1 3.33Å; Y384-H449 WeakPolarHBondContact CE2-CE1 3.43Å; Y384-H449 AromaticContact CE2-ND1 3.96Å; Y384-H449 AromaticContact CG-CE1 3.89Å; Y384-H449 AromaticContact CZ-CE1 3.43Å; Y384-H449 VanDerWaalsContact CZ-CE1 3.43Å; Y384-H449 PolarHBondContact O-NE2 2.84Å
385H98.7Very high97.6Very high33 Ų3310.5 Ų10.515%0.1536%0.055CC..THydrogen-bonded Turntrans-92.31.5179.6-63-64.4000114.2N359 L362 G363 E381 I383 I387N359-H385 PolarHBondContact O-NE2 2.94Å; N359-H385 VanDerWaalsContact O-NE2 3.17Å; N359-H385 PolarHBondContact OD1-NE2 2.88Å; L362-H385 HydrophobicContact CB-CB 4.29Å; L362-H385 WeakPolarHBondContact O-CB 3.29Å; G363-H385 VanDerWaalsContact CA-CG 3.42Å; G363-H385 WeakPolarHBondContact CA-ND1 3.46Å; E381-H385 PolarHBondContact O-CD2 3.36Å; E381-H385 PolarHBondContact O-N 2.84Å; E381-H385 VanDerWaalsContact O-N 3.08Å; I383-H385 VanDerWaalsContact C-N 3.28Å; I383-H385 PolarHBondContact O-N 2.91Å; H385-I387 HydrophobicContact CB-CG1 4.06Å
386G98.6Very high97.4Very high0 Ų012.8 Ų12.80%07%0.073CC..THydrogen-bonded Turntrans64.140.7178.400000114.1A382 I383 K438 V441A382-G386 CarbonylContact O-C 3.58Å; A382-G386 WeakPolarHBondContact O-CA 3.25Å; A382-G386 PolarHBondContact O-N 3.3Å; I383-G386 PolarHBondContact O-N 2.86Å; G386-K438 PolarHBondContact O-NZ 3.36Å; G386-V441 VanDerWaalsContact C-CG1 3.45Å; G386-V441 VanDerWaalsContact O-CG1 3.22Å; G386-V441 WeakPolarHBondContact O-CG1 3.33Å
387I98.8Very high97.3Very high5 Ų513.4 Ų13.43%0.0268%0.076CC..  trans-103.2121.9-177.2-55.5-54.7000110.7L362 T367 F370 A382 H385L362-I387 HydrophobicContact CB-CG1 4.45Å; L362-I387 HydrophobicContact CD2-CB 4.39Å; L362-I387 HydrophobicContact CD2-CG1 4.34Å; L362-I387 HydrophobicContact CD2-CG2 4.19Å; L362-I387 WeakPolarHBondContact O-CD1 3.25Å; L362-I387 VanDerWaalsContact O-CG1 3.29Å; L362-I387 WeakPolarHBondContact O-CG1 3.24Å; T367-I387 HydrophobicContact CG2-CD1 3.94Å; T367-I387 HydrophobicContact CG2-CG1 4.12Å; T367-I387 HydrophobicContact CG2-CG2 3.92Å; F370-I387 HydrophobicContact CB-CG2 3.87Å; A382-I387 PolarHBondContact O-N 3.5Å; H385-I387 HydrophobicContact CB-CG1 4.06Å
388P98.6Very high97.5Very high2 Ų212.1 Ų12.11%0.0137%0.068CC..  trans-71.7157177.931.9-35.8000111.1K368 A369 F370 V431 V441K368-P388 WeakPolarHBondContact O-CD 3.44Å; K368-P388 WeakPolarHBondContact O-CG 3.15Å; A369-P388 WeakPolarHBondContact CA-O 3.33Å; F370-P388 PolarHBondContact N-O 3.33Å; P388-V431 HydrophobicContact CB-CB 4.37Å; P388-V441 HydrophobicContact CB-CG1 4.31Å
389M98.7Very high97.5Very high0 Ų013.3 Ų13.30%08%0.076CC..EExtended strand (participates in β ladder)trans-123.7145-166.1-70171.5-78.400114.3F370 T372 I379 A382 M405 A410 A411 V412F370-M389 HydrophobicContact CB-CG 4.11Å; F370-M389 HydrophobicContact CD1-CG 4.07Å; F370-M389 HydrophobicContact CD1-SD 4.3Å; F370-M389 CarbonylContact O-C 3.58Å; F370-M389 WeakPolarHBondContact O-CA 3.35Å; T372-M389 HydrophobicContact CG2-CB 4.14Å; T372-M389 HydrophobicContact CG2-CG 4.11Å; T372-M389 HydrophobicContact CG2-SD 4.01Å; I379-M389 HydrophobicContact CG1-SD 4.11Å; I379-M389 HydrophobicContact CG2-CE 4.5Å; A382-M389 HydrophobicContact CB-CE 4.05Å; A382-M389 HydrophobicContact CB-CG 3.94Å; A382-M389 HydrophobicContact CB-SD 3.52Å; A382-M389 VanDerWaalsContact CB-SD 3.52Å; M389-M405 HydrophobicContact CE-CB 4.41Å; M389-M405 HydrophobicContact CE-CE 3.28Å; M389-M405 HydrophobicContact CE-CG 3.93Å; M389-M405 HydrophobicContact CE-SD 4.18Å; M389-A410 PolarHBondContact N-O 3.29Å; M389-A410 VanDerWaalsContact N-O 3.08Å; M389-A411 HydrophobicContact CB-CB 3.99Å; M389-A411 CarbonylContact O-C 3.46Å; M389-A411 WeakPolarHBondContact O-CA 3.22Å; M389-A411 WeakPolarHBondContact O-CB 3.22Å; M389-V412 PolarHBondContact O-N 3.37Å
390V98.9Very high97.4Very high0 Ų013.8 Ų13.80%08%0.078CC..EExtended strand (participates in β ladder)trans-106.5115.1156.3-178.40000107.2F370 I371 T372 V412 Q414 L424 A427 I428 V431F370-V390 PolarHBondContact O-N 3.43Å; I371-V390 WeakPolarHBondContact CA-O 3.45Å; I371-V390 HydrophobicContact CG1-CB 4.41Å; T372-V390 PolarHBondContact N-O 2.98Å; V390-V412 CarbonylContact C-O 3.59Å; V390-V412 WeakPolarHBondContact CA-O 3.31Å; V390-Q414 HydrophobicContact CG1-CG 3.94Å; V390-L424 HydrophobicContact CG1-CD1 4.05Å; V390-A427 HydrophobicContact CG1-CB 4.09Å; V390-A427 HydrophobicContact CG2-CB 4.37Å; V390-I428 HydrophobicContact CG2-CG1 3.95Å; V390-V431 HydrophobicContact CG2-CG1 4.05Å; V390-V431 HydrophobicContact CG2-CG2 3.64Å
391G98.6Very high97.4Very high0 Ų013.7 Ų13.70%08%0.078CC..EExtended strand (participates in β ladder)trans-90.1129.2-179.800000111.9T372 M402 V412 I413 Q414T372-G391 CarbonylContact O-C 3.42Å; T372-G391 VanDerWaalsContact O-CA 3.3Å; T372-G391 WeakPolarHBondContact O-CA 3.13Å; G391-M402 VanDerWaalsContact CA-CE 3.48Å; G391-V412 PolarHBondContact N-O 2.77Å; G391-I413 CarbonylContact O-C 3.58Å; G391-Q414 PolarHBondContact O-N 3.26Å
392I98.4Very high97.4Very high1 Ų112.4 Ų12.41%0.0057%0.072CC..  trans-122.479.8169.2-39.8179.3000106.5L308 I371 T372 H373 M394 Q414 L416 M419 L424L308-I392 HydrophobicContact CD2-CB 4.49Å; I371-I392 HydrophobicContact CG2-CD1 3.73Å; I371-I392 HydrophobicContact CG2-CG1 4.14Å; T372-I392 PolarHBondContact O-N 3.29Å; H373-I392 VanDerWaalsContact CA-O 3.3Å; H373-I392 WeakPolarHBondContact CA-O 3.28Å; I392-M394 HydrophobicContact CB-CE 3.72Å; I392-M394 HydrophobicContact CG2-CE 3.25Å; I392-M394 WeakPolarHBondContact O-CE 3.31Å; I392-Q414 HydrophobicContact CG1-CB 4.33Å; I392-L416 HydrophobicContact CG2-CB 4.13Å; I392-M419 HydrophobicContact CD1-CE 4.22Å; I392-M419 HydrophobicContact CD1-SD 4.1Å; I392-M419 HydrophobicContact CG2-CE 4.15Å; I392-M419 HydrophobicContact CG2-SD 3.85Å; I392-L424 HydrophobicContact CD1-CD1 4.1Å
393P97.1Very high97.4Very high23 Ų2313.8 Ų13.815%0.1498%0.08CC..  trans-65.2141.9-176.728.1-35.5000111.9H373 Q398 P399 M402 I413 Q414H373-P393 WeakPolarHBondContact O-CA 3.18Å; P393-Q398 HydrophobicContact CB-CB 3.74Å; P393-P399 HydrophobicContact CB-CB 4.2Å; P393-P399 HydrophobicContact CB-CG 3.89Å; P393-P399 HydrophobicContact CG-CB 4.36Å; P393-P399 HydrophobicContact CG-CG 4.41Å; P393-M402 HydrophobicContact CB-CG 4.47Å; P393-I413 HydrophobicContact CG-CG2 4.24Å; P393-Q414 WeakPolarHBondContact CD-O 3.37Å
394M94.1Very high97.4Very high7 Ų714 Ų143%0.0348%0.081CC..  trans-116.4-41.3-172-56.8-76.5123.100112.6S95 M96 L308 V312 L315 H373 I392 Q398 L416S95-M394 CarbonylContact C-O 3.56Å; M96-M394 HydrophobicContact CE-SD 3.83Å; M96-M394 HydrophobicContact CG-CB 4.03Å; M96-M394 WeakPolarHBondContact CG-O 3.29Å; M96-M394 HydrophobicContact SD-CB 4.42Å; L308-M394 HydrophobicContact CD1-CE 4.34Å; L308-M394 HydrophobicContact CD1-SD 4.19Å; L308-M394 HydrophobicContact CD2-CE 4.05Å; L308-M394 HydrophobicContact CD2-CG 4.45Å; V312-M394 HydrophobicContact CG2-CB 4.43Å; V312-M394 HydrophobicContact CG2-CG 4.35Å; L315-M394 HydrophobicContact CD2-SD 4.48Å; H373-M394 HydrophobicContact CB-CG 4.02Å; I392-M394 HydrophobicContact CB-CE 3.72Å; I392-M394 HydrophobicContact CG2-CE 3.25Å; I392-M394 WeakPolarHBondContact O-CE 3.31Å; M394-Q398 VanDerWaalsContact CB-OE1 3.29Å; M394-L416 HydrophobicContact CE-CB 3.86Å; M394-L416 HydrophobicContact CE-CD1 4.02Å; M394-L416 HydrophobicContact CE-CD2 3.99Å; M394-L416 HydrophobicContact CE-CG 4.15Å; M394-L416 HydrophobicContact SD-CD2 3.7Å; M394-L416 HydrophobicContact SD-CG 4.48Å
395F93.4Very high97.4Very high26 Ų2612.2 Ų12.211%0.1147%0.074CC..SBendtrans-163.3171.6-175.265.4-86.8000112.6L92 S95 M311 V312 D397 Q398L92-F395 HydrophobicContact CD2-CB 4.35Å; L92-F395 HydrophobicContact CD2-CD1 3.44Å; L92-F395 VanDerWaalsContact CD2-CD1 3.44Å; L92-F395 HydrophobicContact CD2-CD2 4.18Å; L92-F395 HydrophobicContact CD2-CE1 3.68Å; L92-F395 HydrophobicContact CD2-CE2 4.39Å; L92-F395 HydrophobicContact CD2-CG 3.74Å; L92-F395 HydrophobicContact CD2-CZ 4.17Å; S95-F395 VanDerWaalsContact CB-CB 3.47Å; M311-F395 HydrophobicContact CB-CE1 4.33Å; M311-F395 HydrophobicContact CB-CZ 4.02Å; M311-F395 HydrophobicContact CG-CZ 4.39Å; M311-F395 HydrophobicContact SD-CE2 3.78Å; M311-F395 HydrophobicContact SD-CZ 3.48Å; M311-F395 WeakPolarHBondContact SD-CZ 3.4Å; V312-F395 HydrophobicContact CG2-CD1 4.43Å; V312-F395 HydrophobicContact CG2-CE1 3.99Å; F395-D397 PolarHBondContact O-N 3.01Å; F395-Q398 VanDerWaalsContact CD1-NE2 3.31Å; F395-Q398 VanDerWaalsContact N-OE1 3.14Å; F395-Q398 VanDerWaalsContact O-CB 3.25Å; F395-Q398 WeakPolarHBondContact O-CB 3.46Å; F395-Q398 VanDerWaalsContact O-CG 3.29Å; F395-Q398 WeakPolarHBondContact O-CG 3.4Å; F395-Q398 PolarHBondContact O-N 3.25Å; F395-Q398 PolarHBondContact O-NE2 2.94Å
396A93.3Very high97.4Very high55 Ų5515.2 Ų15.246%0.4559%0.088SC..THydrogen-bonded Turntrans49.8-127.5174.300000113.6M197 Q398 P399M197-A396 VanDerWaalsContact CE-C 3.41Å; M197-A396 WeakPolarHBondContact CE-O 3.29Å; A396-Q398 VanDerWaalsContact C-N 3.27Å; A396-Q398 PolarHBondContact O-N 3Å; A396-P399 VanDerWaalsContact O-CD 3.31Å; A396-P399 WeakPolarHBondContact O-CD 3.46Å
397D94.6Very high97.4Very high27 Ų2718 Ų1814%0.14411%0.112CC..THydrogen-bonded Turntrans-76.8-10.1-173.962-47.3000114.7F173 M197 T376 F395 D400 N401F173-D397 HydrophobicContact CE1-CB 3.43Å; F173-D397 VanDerWaalsContact CE1-CB 3.43Å; F173-D397 HydrophobicContact CZ-CB 3.57Å; M197-D397 WeakPolarHBondContact SD-CA 3.41Å; M197-D397 HydrophobicContact SD-CB 3.84Å; T376-D397 PolarHBondContact OG1-OD2 3.49Å; F395-D397 PolarHBondContact O-N 3.01Å; D397-D400 WeakPolarHBondContact O-CB 3.3Å; D397-D400 PolarHBondContact O-N 3.45Å; D397-D400 VanDerWaalsContact O-N 3.16Å; D397-N401 PolarHBondContact O-N 3.47Å; D397-N401 PolarHBondContact O-ND2 2.98Å; D397-N401 PolarHBondContact OD2-ND2 3.36Å
398Q97.5Very high97.3Very high3 Ų319.3 Ų19.31%0.01412%0.117CC..Hα-helixtrans-58.3-45.2-172.2-69159.832.500114.1H373 P393 M394 F395 A396 D400 N401 M402H373-Q398 VanDerWaalsContact CD2-CD 3.42Å; H373-Q398 PolarHBondContact CD2-NE2 3.43Å; H373-Q398 VanDerWaalsContact CD2-NE2 3.33Å; H373-Q398 WeakPolarHBondContact O-CB 3.4Å; H373-Q398 VanDerWaalsContact O-CG 3.25Å; H373-Q398 WeakPolarHBondContact O-CG 3.28Å; H373-Q398 PolarHBondContact O-OE1 3.35Å; P393-Q398 HydrophobicContact CB-CB 3.74Å; M394-Q398 VanDerWaalsContact CB-OE1 3.29Å; F395-Q398 VanDerWaalsContact CD1-NE2 3.31Å; F395-Q398 VanDerWaalsContact N-OE1 3.14Å; F395-Q398 VanDerWaalsContact O-CB 3.25Å; F395-Q398 WeakPolarHBondContact O-CB 3.46Å; F395-Q398 VanDerWaalsContact O-CG 3.29Å; F395-Q398 WeakPolarHBondContact O-CG 3.4Å; F395-Q398 PolarHBondContact O-N 3.25Å; F395-Q398 PolarHBondContact O-NE2 2.94Å; A396-Q398 VanDerWaalsContact C-N 3.27Å; A396-Q398 PolarHBondContact O-N 3Å; Q398-D400 VanDerWaalsContact C-N 3.32Å; Q398-D400 PolarHBondContact O-N 3.5Å; Q398-N401 PolarHBondContact O-N 3.45Å; Q398-M402 WeakPolarHBondContact O-CG 3.41Å; Q398-M402 PolarHBondContact O-N 2.96Å
399P97.3Very high97.3Very high30 Ų3020.1 Ų20.120%0.19513%0.126CC..Hα-helixtrans-61.1-42.2177.1-2031.6000112.3K199 P393 A396 M402 V403K199-P399 HydrophobicContact CD-CB 4.12Å; P393-P399 HydrophobicContact CB-CB 4.2Å; P393-P399 HydrophobicContact CB-CG 3.89Å; P393-P399 HydrophobicContact CG-CB 4.36Å; P393-P399 HydrophobicContact CG-CG 4.41Å; A396-P399 VanDerWaalsContact O-CD 3.31Å; A396-P399 WeakPolarHBondContact O-CD 3.46Å; P399-M402 PolarHBondContact O-N 2.6Å; P399-V403 PolarHBondContact O-N 2.68Å; P399-V403 VanDerWaalsContact O-N 3.12Å
400D97.6Very high97.3Very high10 Ų1020.1 Ų20.15%0.05313%0.126CC..Hα-helixtrans-65.1-46.9179.8-170.675.7000110.8K199 D397 Q398 M402 V403 H404K199-D400 VanDerWaalsContact CA-OD1 3.24Å; K199-D400 WeakPolarHBondContact CA-OD1 3.22Å; K199-D400 PolarHBondContact N-OD1 2.87Å; D397-D400 WeakPolarHBondContact O-CB 3.3Å; D397-D400 PolarHBondContact O-N 3.45Å; D397-D400 VanDerWaalsContact O-N 3.16Å; Q398-D400 VanDerWaalsContact C-N 3.32Å; Q398-D400 PolarHBondContact O-N 3.5Å; D400-M402 VanDerWaalsContact C-N 3.27Å; D400-M402 PolarHBondContact O-N 3.11Å; D400-V403 WeakPolarHBondContact O-CB 2.88Å; D400-V403 PolarHBondContact O-N 2.95Å; D400-V403 VanDerWaalsContact O-N 3.13Å; D400-H404 PolarHBondContact O-N 3.4Å; D400-H404 PolarHBondContact O-ND1 3.09Å; D400-H404 IonicContact OD2-CE1 2.67Å; D400-H404 PolarHBondContact OD2-CE1 2.75Å; D400-H404 IonicContact OD2-ND1 3.73Å
401N98.2Very high97.3Very high0 Ų020.1 Ų20.10%013%0.126CC..Hα-helixtrans-58-39.5175.1-65.8-24000112.3R172 F263 G374 T376 I379 D397 Q398 V403 H404 M405R172-N401 PolarHBondContact NH2-OD1 3.42Å; F263-N401 HydrophobicContact CE2-CB 4.17Å; F263-N401 HydrophobicContact CZ-CB 3.79Å; F263-N401 WeakPolarHBondContact CZ-OD1 3.38Å; G374-N401 WeakPolarHBondContact O-CB 3.29Å; G374-N401 PolarHBondContact O-ND2 2.91Å; T376-N401 PolarHBondContact OG1-ND2 3.39Å; I379-N401 HydrophobicContact CD1-CB 3.58Å; D397-N401 PolarHBondContact O-N 3.47Å; D397-N401 PolarHBondContact O-ND2 2.98Å; D397-N401 PolarHBondContact OD2-ND2 3.36Å; Q398-N401 PolarHBondContact O-N 3.45Å; N401-V403 VanDerWaalsContact C-N 3.35Å; N401-H404 WeakPolarHBondContact O-CB 3.25Å; N401-H404 PolarHBondContact O-N 3.4Å; N401-M405 PolarHBondContact O-N 3.42Å
402M98.3Very high97.3Very high0 Ų021.2 Ų21.20%013%0.132CC..Hα-helixtrans-68.6-34.5179.1-72.4-50-44.800112.2T372 G374 I379 G391 P393 Q398 P399 D400 H404 M405 E406 A411 I413T372-M402 HydrophobicContact CG2-SD 4.38Å; G374-M402 WeakPolarHBondContact CA-SD 3.25Å; I379-M402 HydrophobicContact CD1-SD 4.44Å; G391-M402 VanDerWaalsContact CA-CE 3.48Å; P393-M402 HydrophobicContact CB-CG 4.47Å; Q398-M402 WeakPolarHBondContact O-CG 3.41Å; Q398-M402 PolarHBondContact O-N 2.96Å; P399-M402 PolarHBondContact O-N 2.6Å; D400-M402 VanDerWaalsContact C-N 3.27Å; D400-M402 PolarHBondContact O-N 3.11Å; M402-H404 VanDerWaalsContact C-N 3.29Å; M402-H404 PolarHBondContact O-N 3.01Å; M402-M405 HydrophobicContact CE-CB 4.29Å; M402-M405 PolarHBondContact O-N 2.91Å; M402-E406 WeakPolarHBondContact O-CB 3.41Å; M402-E406 PolarHBondContact O-N 2.91Å; M402-A411 HydrophobicContact CE-CB 3.4Å; M402-I413 HydrophobicContact CB-CD1 3.83Å; M402-I413 HydrophobicContact CB-CG1 4Å; M402-I413 HydrophobicContact CB-CG2 4.47Å
403V98.3Very high97.3Very high28 Ų2823.2 Ų23.217%0.1714%0.143CC..Hα-helixtrans-59.5-40.5171.2169.60000111.1K199 T201 P399 D400 N401 M405 E406 A407 I413K199-V403 HydrophobicContact CB-CG2 4.15Å; T201-V403 HydrophobicContact CG2-CG1 3.91Å; P399-V403 PolarHBondContact O-N 2.68Å; P399-V403 VanDerWaalsContact O-N 3.12Å; D400-V403 WeakPolarHBondContact O-CB 2.88Å; D400-V403 PolarHBondContact O-N 2.95Å; D400-V403 VanDerWaalsContact O-N 3.13Å; N401-V403 VanDerWaalsContact C-N 3.35Å; V403-M405 VanDerWaalsContact C-N 3.35Å; V403-M405 PolarHBondContact O-N 2.85Å; V403-E406 PolarHBondContact O-N 3.12Å; V403-A407 VanDerWaalsContact O-CB 3.28Å; V403-A407 WeakPolarHBondContact O-CB 3.38Å; V403-A407 PolarHBondContact O-N 2.94Å; V403-I413 HydrophobicContact CG2-CD1 4.23Å
404H98.3Very high97.3Very high6 Ų623.5 Ų23.53%0.02814%0.142CC..Hα-helixtrans-61.9-43.6176.3-68.363.8000111.5F263 D264 F265 D400 N401 M402 A407 K408F263-H404 HydrophobicContact CD2-CB 4.38Å; F263-H404 HydrophobicContact CE2-CB 3.92Å; D264-H404 IonicContact OD1-NE2 3.6Å; F265-H404 AromaticContact CD2-CD2 3.48Å; F265-H404 VanDerWaalsContact CD2-CD2 3.48Å; F265-H404 WeakPolarHBondContact CD2-CD2 3.4Å; F265-H404 AromaticContact CD2-NE2 3.48Å; F265-H404 WeakPolarHBondContact CD2-NE2 3.28Å; F265-H404 AromaticContact CE2-CD2 3.21Å; F265-H404 WeakPolarHBondContact CE2-CD2 3.28Å; F265-H404 AromaticContact CE2-CE1 3.97Å; F265-H404 AromaticContact CE2-CG 3.75Å; F265-H404 AromaticContact CE2-NE2 3.38Å; F265-H404 WeakPolarHBondContact CE2-NE2 3.31Å; F265-H404 AromaticContact CZ-CD2 3.94Å; D400-H404 PolarHBondContact O-N 3.4Å; D400-H404 PolarHBondContact O-ND1 3.09Å; D400-H404 IonicContact OD2-CE1 2.67Å; D400-H404 PolarHBondContact OD2-CE1 2.75Å; D400-H404 IonicContact OD2-ND1 3.73Å; N401-H404 WeakPolarHBondContact O-CB 3.25Å; N401-H404 PolarHBondContact O-N 3.4Å; M402-H404 VanDerWaalsContact C-N 3.29Å; M402-H404 PolarHBondContact O-N 3.01Å; H404-A407 PolarHBondContact O-N 3.43Å; H404-K408 WeakPolarHBondContact O-CG 3.28Å; H404-K408 PolarHBondContact O-N 2.9Å; H404-K408 VanDerWaalsContact O-N 3.08Å
405M98.6Very high97.5Very high0 Ų025.7 Ų25.70%015%0.154CC..Hα-helixtrans-70.9-34.8179.7-67.3-48.6-60.500113.3F263 I379 I383 M389 N401 M402 V403 K408 G409 A410 A411 L444F263-M405 HydrophobicContact CD2-CG 4.37Å; F263-M405 HydrophobicContact CD2-SD 3.66Å; F263-M405 HydrophobicContact CE2-CG 4.29Å; F263-M405 HydrophobicContact CE2-SD 4.17Å; I379-M405 HydrophobicContact CD1-CG 4.08Å; I379-M405 HydrophobicContact CG1-CG 4.39Å; I379-M405 HydrophobicContact CG2-CG 3.99Å; I379-M405 HydrophobicContact CG2-SD 3.69Å; I383-M405 HydrophobicContact CD1-CE 4.03Å; I383-M405 HydrophobicContact CD1-SD 4.01Å; I383-M405 HydrophobicContact CG1-CE 3.96Å; M389-M405 HydrophobicContact CE-CB 4.41Å; M389-M405 HydrophobicContact CE-CE 3.28Å; M389-M405 HydrophobicContact CE-CG 3.93Å; M389-M405 HydrophobicContact CE-SD 4.18Å; N401-M405 PolarHBondContact O-N 3.42Å; M402-M405 HydrophobicContact CE-CB 4.29Å; M402-M405 PolarHBondContact O-N 2.91Å; V403-M405 VanDerWaalsContact C-N 3.35Å; V403-M405 PolarHBondContact O-N 2.85Å; M405-K408 PolarHBondContact O-N 3.41Å; M405-G409 PolarHBondContact O-N 2.87Å; M405-A410 HydrophobicContact CE-CB 3.59Å; M405-A410 PolarHBondContact O-N 2.84Å; M405-A411 HydrophobicContact CB-CB 3.72Å; M405-A411 PolarHBondContact O-N 3.05Å; M405-L444 HydrophobicContact CE-CD1 3.73Å
406E98.4Very high97.6Very high96 Ų9624.7 Ų24.745%0.44915%0.15SC..Hα-helixtrans-67.6-44.1173.1-175.5172.6-110.600111.2M402 V403 K408 G409 I413M402-E406 WeakPolarHBondContact O-CB 3.41Å; M402-E406 PolarHBondContact O-N 2.91Å; V403-E406 PolarHBondContact O-N 3.12Å; E406-K408 PolarHBondContact O-N 2.86Å; E406-G409 WeakPolarHBondContact O-CA 3.33Å; E406-G409 PolarHBondContact O-N 3.43Å; E406-I413 HydrophobicContact CB-CD1 3.99Å; E406-I413 HydrophobicContact CB-CG1 4.14Å; E406-I413 WeakPolarHBondContact OE2-CD1 3.5Å
407A98.2Very high97.8Very high60 Ų6023.1 Ų23.150%0.49613%0.134SC..Hα-helixtrans-60.8-31.1175.200000112.8T201 F265 V403 H404 G409T201-A407 HydrophobicContact CG2-CB 3.87Å; F265-A407 HydrophobicContact CE1-CB 4.42Å; F265-A407 HydrophobicContact CZ-CB 4.1Å; V403-A407 VanDerWaalsContact O-CB 3.28Å; V403-A407 WeakPolarHBondContact O-CB 3.38Å; V403-A407 PolarHBondContact O-N 2.94Å; H404-A407 PolarHBondContact O-N 3.43Å; A407-G409 VanDerWaalsContact C-N 3.27Å
408K98Very high97.9Very high31 Ų3127.7 Ų27.714%0.13515%0.153CC..THydrogen-bonded Turntrans-83.21.2172.2-66.7-178.2-164.8-85.70113.6W261 D262 F263 D264 H404 M405 E406 A410 L444W261-K408 PolarHBondContact O-NZ 3.29Å; D262-K408 WeakPolarHBondContact O-CD 3.17Å; D262-K408 WeakPolarHBondContact O-CE 3.39Å; D262-K408 PolarHBondContact O-NZ 3.44Å; F263-K408 WeakPolarHBondContact O-CE 3.21Å; D264-K408 PolarHBondContact O-NZ 3.39Å; H404-K408 WeakPolarHBondContact O-CG 3.28Å; H404-K408 PolarHBondContact O-N 2.9Å; H404-K408 VanDerWaalsContact O-N 3.08Å; M405-K408 PolarHBondContact O-N 3.41Å; E406-K408 PolarHBondContact O-N 2.86Å; K408-A410 VanDerWaalsContact C-N 3.28Å; K408-A410 PolarHBondContact O-N 2.82Å; K408-L444 HydrophobicContact CB-CD1 4.07Å; K408-L444 HydrophobicContact CD-CD1 3.84Å; K408-L444 HydrophobicContact CD-CD2 3.93Å
409G98.2Very high97.8Very high19 Ų1928.1 Ų28.120%0.19615%0.154CC..THydrogen-bonded Turntrans66.726.2177.200000113.9M405 E406 A407 Y437 N440M405-G409 PolarHBondContact O-N 2.87Å; E406-G409 WeakPolarHBondContact O-CA 3.33Å; E406-G409 PolarHBondContact O-N 3.43Å; A407-G409 VanDerWaalsContact C-N 3.27Å; G409-Y437 WeakPolarHBondContact O-CA 3.48Å; G409-Y437 VanDerWaalsContact O-CD1 3.23Å; G409-Y437 WeakPolarHBondContact O-CD1 3.42Å; G409-N440 WeakPolarHBondContact O-CB 2.87Å; G409-N440 PolarHBondContact O-ND2 3.21Å
410A98.4Very high97.9Very high0 Ų029.7 Ų29.70%016%0.164CC..SBendtrans-111.3-1.6-176.100000113.2M389 M405 K408 V441 L444M389-A410 PolarHBondContact N-O 3.29Å; M389-A410 VanDerWaalsContact N-O 3.08Å; M405-A410 HydrophobicContact CE-CB 3.59Å; M405-A410 PolarHBondContact O-N 2.84Å; K408-A410 VanDerWaalsContact C-N 3.28Å; K408-A410 PolarHBondContact O-N 2.82Å; A410-V441 HydrophobicContact CB-CB 4.01Å; A410-V441 HydrophobicContact CB-CG2 4.37Å; A410-L444 HydrophobicContact CB-CD1 4.1Å
411A98.5Very high97.9Very high1 Ų130.4 Ų30.41%0.00817%0.169CC..EExtended strand (participates in β ladder)trans-146.4161.1178.300000114M389 M402 M405M389-A411 HydrophobicContact CB-CB 3.99Å; M389-A411 CarbonylContact O-C 3.46Å; M389-A411 WeakPolarHBondContact O-CA 3.22Å; M389-A411 WeakPolarHBondContact O-CB 3.22Å; M402-A411 HydrophobicContact CE-CB 3.4Å; M405-A411 HydrophobicContact CB-CB 3.72Å; M405-A411 PolarHBondContact O-N 3.05Å
412V98.6Very high97.9Very high22 Ų2234.7 Ų34.713%0.13319%0.189CC..EExtended strand (participates in β ladder)trans-117.8134.9164.9174.60000108.5M389 V390 G391 A427 V431 Y437M389-V412 PolarHBondContact O-N 3.37Å; V390-V412 CarbonylContact C-O 3.59Å; V390-V412 WeakPolarHBondContact CA-O 3.31Å; G391-V412 PolarHBondContact N-O 2.77Å; V412-A427 HydrophobicContact CB-CB 4.43Å; V412-A427 HydrophobicContact CG1-CB 3.8Å; V412-V431 HydrophobicContact CB-CG1 4.15Å; V412-V431 HydrophobicContact CG2-CG1 3.68Å; V412-Y437 HydrophobicContact CG2-CE1 3.83Å; V412-Y437 HydrophobicContact CG2-CE2 4.37Å; V412-Y437 VanDerWaalsContact CG2-OH 3.23Å; V412-Y437 WeakPolarHBondContact CG2-OH 3.37Å
413I98.4Very high97.9Very high44 Ų4436.5 Ų36.523%0.22620%0.201CC..EExtended strand (participates in β ladder)trans-94.7139.4-180-46.4-178000110.2G391 P393 M402 V403 E406G391-I413 CarbonylContact O-C 3.58Å; P393-I413 HydrophobicContact CG-CG2 4.24Å; M402-I413 HydrophobicContact CB-CD1 3.83Å; M402-I413 HydrophobicContact CB-CG1 4Å; M402-I413 HydrophobicContact CB-CG2 4.47Å; V403-I413 HydrophobicContact CG2-CD1 4.23Å; E406-I413 HydrophobicContact CB-CD1 3.99Å; E406-I413 HydrophobicContact CB-CG1 4.14Å; E406-I413 WeakPolarHBondContact OE2-CD1 3.5Å
414Q98.4Very high98Very high28 Ų2835.2 Ų35.213%0.13119%0.193CC..  trans-124.1141.5169.2-65.1-63.9-7200109V390 G391 I392 P393 M419 S423 L424 A427V390-Q414 HydrophobicContact CG1-CG 3.94Å; G391-Q414 PolarHBondContact O-N 3.26Å; I392-Q414 HydrophobicContact CG1-CB 4.33Å; P393-Q414 WeakPolarHBondContact CD-O 3.37Å; Q414-M419 HydrophobicContact CB-CB 4.27Å; Q414-M419 HydrophobicContact CB-SD 4.04Å; Q414-S423 PolarHBondContact OE1-OG 3.19Å; Q414-L424 HydrophobicContact CG-CD1 4.36Å; Q414-A427 HydrophobicContact CG-CB 4.2Å
415N96.9Very high98Very high54 Ų5437.1 Ų37.129%0.28920%0.2SC..  trans-92.4125.3172.6176.6-65.8000109.4D100 N417 F418 M419D100-N415 PolarHBondContact OD2-ND2 3.43Å; D100-N415 PolarHBondContact OD2-OD1 3.27Å; N415-N417 VanDerWaalsContact C-N 3.26Å; N415-N417 PolarHBondContact O-N 3.41Å; N415-N417 WeakPolarHBondContact OD1-CA 3.41Å; N415-N417 WeakPolarHBondContact OD1-CB 3.21Å; N415-N417 PolarHBondContact OD1-N 2.61Å; N415-F418 HydrophobicContact CB-CB 4.38Å; N415-F418 HydrophobicContact CB-CD2 4.04Å; N415-F418 PolarHBondContact O-N 3.45Å; N415-F418 WeakPolarHBondContact OD1-CD2 3.48Å; N415-F418 PolarHBondContact OD1-N 2.94Å; N415-M419 WeakPolarHBondContact O-CB 3.18Å; N415-M419 VanDerWaalsContact O-CG 3.26Å; N415-M419 WeakPolarHBondContact O-CG 3.45Å; N415-M419 PolarHBondContact O-N 2.81Å
416L96.5Very high98Very high4 Ų440.6 Ų40.62%0.02122%0.219CC..THydrogen-bonded Turntrans-52.5-43-178.6174.765.2000113M96 Y97 L315 K319 I392 M394 M419M96-L416 HydrophobicContact CB-CD2 4.4Å; M96-L416 HydrophobicContact CE-CD2 4.15Å; Y97-L416 HydrophobicContact CE1-CD2 4.25Å; L315-L416 HydrophobicContact CD2-CD1 4.46Å; K319-L416 HydrophobicContact CB-CD1 4.42Å; K319-L416 HydrophobicContact CD-CD1 4.32Å; K319-L416 WeakPolarHBondContact CD-O 3.42Å; K319-L416 VanDerWaalsContact CE-O 3.28Å; K319-L416 WeakPolarHBondContact CE-O 3.28Å; K319-L416 HydrophobicContact CG-CD1 4.35Å; K319-L416 PolarHBondContact NZ-O 3.4Å; I392-L416 HydrophobicContact CG2-CB 4.13Å; M394-L416 HydrophobicContact CE-CB 3.86Å; M394-L416 HydrophobicContact CE-CD1 4.02Å; M394-L416 HydrophobicContact CE-CD2 3.99Å; M394-L416 HydrophobicContact CE-CG 4.15Å; M394-L416 HydrophobicContact SD-CD2 3.7Å; M394-L416 HydrophobicContact SD-CG 4.48Å; L416-M419 HydrophobicContact CD1-CE 3.91Å
417N96.1Very high98Very high22 Ų2236.3 Ų36.312%0.11820%0.2CC..THydrogen-bonded Turntrans-76.9-31.7-173.9-68.2-45.8000112.4M96 D100 F101 K319 N415M96-N417 PolarHBondContact O-ND2 2.95Å; M96-N417 PolarHBondContact O-OD1 2.88Å; D100-N417 PolarHBondContact OD2-ND2 2.89Å; F101-N417 HydrophobicContact CE2-CB 4.3Å; F101-N417 HydrophobicContact CZ-CB 3.96Å; K319-N417 PolarHBondContact NZ-O 3.24Å; N415-N417 VanDerWaalsContact C-N 3.26Å; N415-N417 PolarHBondContact O-N 3.41Å; N415-N417 WeakPolarHBondContact OD1-CA 3.41Å; N415-N417 WeakPolarHBondContact OD1-CB 3.21Å; N415-N417 PolarHBondContact OD1-N 2.61Å
418F96.6Very high98Very high124 Ų12433.4 Ų33.454%0.54418%0.176SC..THydrogen-bonded Turntrans-109.2-10.3-174.6-50.9-57.2000115.4D100 F101 N415D100-F418 HydrophobicContact CB-CE2 4.03Å; D100-F418 HydrophobicContact CB-CZ 4.05Å; F101-F418 AromaticContact CE1-CE1 3.8Å; F101-F418 HydrophobicContact CE1-CE1 3.8Å; F101-F418 HydrophobicContact CE1-CZ 4.11Å; F101-F418 HydrophobicContact CZ-CE1 4.34Å; N415-F418 HydrophobicContact CB-CB 4.38Å; N415-F418 HydrophobicContact CB-CD2 4.04Å; N415-F418 PolarHBondContact O-N 3.45Å; N415-F418 WeakPolarHBondContact OD1-CD2 3.48Å; N415-F418 PolarHBondContact OD1-N 2.94Å
419M96.9Very high98.1Very high11 Ų1136 Ų365%0.05419%0.187CC..  trans-68.7147.9178.670.8-175.1-173.900111.9M322 I323 I392 Q414 N415 L416M322-M419 HydrophobicContact CE-CE 3.6Å; M322-M419 HydrophobicContact CE-CG 3.67Å; M322-M419 WeakPolarHBondContact CE-O 3.29Å; M322-M419 HydrophobicContact CE-SD 4.5Å; M322-M419 HydrophobicContact SD-CE 3.99Å; M322-M419 HydrophobicContact SD-CG 4.09Å; I323-M419 HydrophobicContact CD1-CE 3.68Å; I323-M419 HydrophobicContact CG1-CE 3.57Å; I392-M419 HydrophobicContact CD1-CE 4.22Å; I392-M419 HydrophobicContact CD1-SD 4.1Å; I392-M419 HydrophobicContact CG2-CE 4.15Å; I392-M419 HydrophobicContact CG2-SD 3.85Å; Q414-M419 HydrophobicContact CB-CB 4.27Å; Q414-M419 HydrophobicContact CB-SD 4.04Å; N415-M419 WeakPolarHBondContact O-CB 3.18Å; N415-M419 VanDerWaalsContact O-CG 3.26Å; N415-M419 WeakPolarHBondContact O-CG 3.45Å; N415-M419 PolarHBondContact O-N 2.81Å; L416-M419 HydrophobicContact CD1-CE 3.91Å
420T98.4Very high98.1Very high64 Ų6437 Ų3739%0.39319%0.192SC..  trans-111.3169.1174.476.10000110.9E422 S423 L424T420-E422 PolarHBondContact O-N 2.94Å; T420-E422 PolarHBondContact OG1-N 3.21Å; T420-E422 PolarHBondContact OG1-OE2 3.08Å; T420-E422 VanDerWaalsContact OG1-OE2 3.12Å; T420-S423 PolarHBondContact N-OG 3.45Å; T420-S423 PolarHBondContact O-N 3.41Å; T420-S423 PolarHBondContact O-OG 3.48Å; T420-S423 PolarHBondContact OG1-N 3.21Å; T420-S423 VanDerWaalsContact OG1-N 3.11Å; T420-L424 PolarHBondContact O-N 3.21Å
421T98.4Very high98.1Very high25 Ų2537.1 Ų37.115%0.15319%0.192CC..Hα-helixtrans-52.6-45.4172.3-57.60000111.3A326 Q329 R425A326-T421 HydrophobicContact CB-CG2 3.95Å; A326-T421 VanDerWaalsContact CB-O 3.26Å; A326-T421 WeakPolarHBondContact CB-O 3.29Å; Q329-T421 VanDerWaalsContact NE2-CG2 3.34Å; T421-R425 WeakPolarHBondContact O-CB 3.3Å; T421-R425 PolarHBondContact O-N 3.41Å; T421-R425 VanDerWaalsContact O-N 3.09Å
422E98.6Very high98.1Very high90 Ų9039 Ų3942%0.42120%0.201SC..Hα-helixtrans-69.5-45.7-178.4-6166.6-142.100110.9T420 L424 R425 D426T420-E422 PolarHBondContact O-N 2.94Å; T420-E422 PolarHBondContact OG1-N 3.21Å; T420-E422 PolarHBondContact OG1-OE2 3.08Å; T420-E422 VanDerWaalsContact OG1-OE2 3.12Å; E422-L424 VanDerWaalsContact C-N 3.33Å; E422-L424 PolarHBondContact O-N 3.43Å; E422-R425 PolarHBondContact O-N 3.27Å; E422-D426 WeakPolarHBondContact O-CB 3.29Å; E422-D426 PolarHBondContact O-N 2.85Å
423S98.3Very high98Very high38 Ų3843.5 Ų43.527%0.26623%0.225SC..Hα-helixtrans-62.5-41.5-178.581.30000111.6Q414 T420 D426 A427Q414-S423 PolarHBondContact OE1-OG 3.19Å; T420-S423 PolarHBondContact N-OG 3.45Å; T420-S423 PolarHBondContact O-N 3.41Å; T420-S423 PolarHBondContact O-OG 3.48Å; T420-S423 PolarHBondContact OG1-N 3.21Å; T420-S423 VanDerWaalsContact OG1-N 3.11Å; S423-D426 PolarHBondContact O-N 2.93Å; S423-A427 VanDerWaalsContact O-CB 3.3Å; S423-A427 WeakPolarHBondContact O-CB 3.39Å; S423-A427 PolarHBondContact O-N 2.83Å
424L98.8Very high98Very high0 Ų045 Ų450%023%0.234CC..Hα-helixtrans-67.2-45.8176.7179.158.2000111.6I323 A326 V390 I392 Q414 T420 E422 D426 A427 I428I323-L424 HydrophobicContact CB-CD2 4.21Å; I323-L424 HydrophobicContact CG1-CD2 3.97Å; I323-L424 HydrophobicContact CG2-CD2 3.88Å; A326-L424 HydrophobicContact CB-CB 4.14Å; A326-L424 HydrophobicContact CB-CD2 4.03Å; A326-L424 HydrophobicContact CB-CG 4.16Å; V390-L424 HydrophobicContact CG1-CD1 4.05Å; I392-L424 HydrophobicContact CD1-CD1 4.1Å; Q414-L424 HydrophobicContact CG-CD1 4.36Å; T420-L424 PolarHBondContact O-N 3.21Å; E422-L424 VanDerWaalsContact C-N 3.33Å; E422-L424 PolarHBondContact O-N 3.43Å; L424-D426 VanDerWaalsContact C-N 3.28Å; L424-D426 PolarHBondContact O-N 2.99Å; L424-A427 PolarHBondContact O-N 3.25Å; L424-I428 HydrophobicContact CD1-CD1 3.95Å; L424-I428 HydrophobicContact CD1-CG1 4.25Å; L424-I428 HydrophobicContact CG-CD1 3.92Å; L424-I428 WeakPolarHBondContact O-CD1 3.42Å; L424-I428 VanDerWaalsContact O-CG1 3.22Å; L424-I428 WeakPolarHBondContact O-CG1 3.41Å; L424-I428 PolarHBondContact O-N 2.88Å
425R98.7Very high98Very high46 Ų4651.1 Ų51.117%0.17426%0.26CS..Hα-helixtrans-56.5-45.4175.8178.4-161.870.6-146.9-9.6111.1A326 Q329 L330 T421 E422 I428 K429A326-R425 HydrophobicContact CB-CB 4.43Å; Q329-R425 HydrophobicContact CB-CG 4.43Å; L330-R425 HydrophobicContact CD2-CG 4.02Å; T421-R425 WeakPolarHBondContact O-CB 3.3Å; T421-R425 PolarHBondContact O-N 3.41Å; T421-R425 VanDerWaalsContact O-N 3.09Å; E422-R425 PolarHBondContact O-N 3.27Å; R425-I428 PolarHBondContact O-N 2.85Å; R425-K429 HydrophobicContact CG-CD 4.36Å; R425-K429 WeakPolarHBondContact O-CG 3.38Å; R425-K429 PolarHBondContact O-N 3.12Å
426D98.7Very high98.1Very high73 Ų7350.6 Ų50.639%0.3926%0.26SS..Hα-helixtrans-74.2-35.7-175.1-64.6-17.4000111.4E422 S423 L424 I428 K429 S430E422-D426 WeakPolarHBondContact O-CB 3.29Å; E422-D426 PolarHBondContact O-N 2.85Å; S423-D426 PolarHBondContact O-N 2.93Å; L424-D426 VanDerWaalsContact C-N 3.28Å; L424-D426 PolarHBondContact O-N 2.99Å; D426-I428 PolarHBondContact O-N 2.92Å; D426-K429 PolarHBondContact O-N 3.13Å; D426-S430 WeakPolarHBondContact O-CB 3.48Å; D426-S430 PolarHBondContact O-N 3.32Å
427A98.8Very high98.2Very high6 Ų652.4 Ų52.45%0.0527%0.267CS..Hα-helixtrans-58.9-45.8169.400000111.7V390 V412 Q414 S423 L424 S430 V431V390-A427 HydrophobicContact CG1-CB 4.09Å; V390-A427 HydrophobicContact CG2-CB 4.37Å; V412-A427 HydrophobicContact CB-CB 4.43Å; V412-A427 HydrophobicContact CG1-CB 3.8Å; Q414-A427 HydrophobicContact CG-CB 4.2Å; S423-A427 VanDerWaalsContact O-CB 3.3Å; S423-A427 WeakPolarHBondContact O-CB 3.39Å; S423-A427 PolarHBondContact O-N 2.83Å; L424-A427 PolarHBondContact O-N 3.25Å; A427-S430 WeakPolarHBondContact O-CB 3.36Å; A427-S430 PolarHBondContact O-N 3Å; A427-V431 PolarHBondContact O-N 3.29Å; A427-V431 VanDerWaalsContact O-N 3.09Å
428I98.8Very high98.3Very high0 Ų055.1 Ų55.10%028%0.278CS..Hα-helixtrans-63.3-45.4177.5-65.2161.2000111I304 L327 L330 I371 V390 L424 R425 D426 S430 V431 I432I304-I428 HydrophobicContact CD1-CG2 3.61Å; L327-I428 HydrophobicContact CD2-CD1 4.04Å; L330-I428 HydrophobicContact CD1-CB 4.18Å; L330-I428 HydrophobicContact CD1-CD1 3.77Å; L330-I428 HydrophobicContact CD1-CG2 3.64Å; L330-I428 HydrophobicContact CD2-CG2 4.35Å; I371-I428 HydrophobicContact CD1-CD1 3.54Å; I371-I428 HydrophobicContact CD1-CG1 4.01Å; I371-I428 HydrophobicContact CG1-CD1 4.36Å; I371-I428 HydrophobicContact CG1-CG1 4.31Å; V390-I428 HydrophobicContact CG2-CG1 3.95Å; L424-I428 HydrophobicContact CD1-CD1 3.95Å; L424-I428 HydrophobicContact CD1-CG1 4.25Å; L424-I428 HydrophobicContact CG-CD1 3.92Å; L424-I428 WeakPolarHBondContact O-CD1 3.42Å; L424-I428 VanDerWaalsContact O-CG1 3.22Å; L424-I428 WeakPolarHBondContact O-CG1 3.41Å; L424-I428 PolarHBondContact O-N 2.88Å; R425-I428 PolarHBondContact O-N 2.85Å; D426-I428 PolarHBondContact O-N 2.92Å; I428-S430 VanDerWaalsContact C-N 3.29Å; I428-S430 PolarHBondContact O-N 2.92Å; I428-V431 VanDerWaalsContact O-CG2 3.28Å; I428-V431 WeakPolarHBondContact O-CG2 3.33Å; I428-V431 PolarHBondContact O-N 2.82Å; I428-I432 HydrophobicContact CG2-CD1 3.74Å; I428-I432 HydrophobicContact CG2-CG1 4.49Å; I428-I432 VanDerWaalsContact O-CG1 3.32Å; I428-I432 WeakPolarHBondContact O-CG1 3.3Å; I428-I432 PolarHBondContact O-N 2.76Å; I428-I432 VanDerWaalsContact O-N 3.16Å
429K98.7Very high98.4Very high84 Ų8455.1 Ų55.137%0.36528%0.279SS..Hα-helixtrans-60.4-39.9175.7-76.4178.3176.9178.30111.7L330 R425 D426 I432 N433L330-K429 HydrophobicContact CD2-CG 4.06Å; R425-K429 HydrophobicContact CG-CD 4.36Å; R425-K429 WeakPolarHBondContact O-CG 3.38Å; R425-K429 PolarHBondContact O-N 3.12Å; D426-K429 PolarHBondContact O-N 3.13Å; K429-I432 PolarHBondContact O-N 2.81Å; K429-N433 VanDerWaalsContact O-CB 3.22Å; K429-N433 WeakPolarHBondContact O-CB 3.43Å; K429-N433 VanDerWaalsContact O-CG 3.29Å; K429-N433 PolarHBondContact O-N 3.31Å; K429-N433 PolarHBondContact O-ND2 2.96Å
430S98.4Very high98.5Very high42 Ų4256.6 Ų56.629%0.29429%0.288SS..Hα-helixtrans-60-52.7178.4-173.20000111.3D426 A427 I428 I432 N433 N434 Y437D426-S430 WeakPolarHBondContact O-CB 3.48Å; D426-S430 PolarHBondContact O-N 3.32Å; A427-S430 WeakPolarHBondContact O-CB 3.36Å; A427-S430 PolarHBondContact O-N 3Å; I428-S430 VanDerWaalsContact C-N 3.29Å; I428-S430 PolarHBondContact O-N 2.92Å; S430-I432 VanDerWaalsContact C-N 3.28Å; S430-I432 PolarHBondContact O-N 3.46Å; S430-N433 PolarHBondContact O-N 2.84Å; S430-N434 VanDerWaalsContact O-CB 3.23Å; S430-N434 WeakPolarHBondContact O-CB 3.24Å; S430-N434 PolarHBondContact O-N 3.3Å; S430-Y437 WeakPolarHBondContact OG-CE2 3.37Å
431V98.4Very high98.5Very high1 Ų153.6 Ų53.61%0.00627%0.269CS..Hα-helixtrans-67.9-26.4-177.3-590000113.7A369 P388 V390 V412 A427 I428 Y437A369-V431 HydrophobicContact CB-CG2 3.89Å; P388-V431 HydrophobicContact CB-CB 4.37Å; V390-V431 HydrophobicContact CG2-CG1 4.05Å; V390-V431 HydrophobicContact CG2-CG2 3.64Å; V412-V431 HydrophobicContact CB-CG1 4.15Å; V412-V431 HydrophobicContact CG2-CG1 3.68Å; A427-V431 PolarHBondContact O-N 3.29Å; A427-V431 VanDerWaalsContact O-N 3.09Å; I428-V431 VanDerWaalsContact O-CG2 3.28Å; I428-V431 WeakPolarHBondContact O-CG2 3.33Å; I428-V431 PolarHBondContact O-N 2.82Å; V431-Y437 HydrophobicContact CB-CD2 4.43Å; V431-Y437 HydrophobicContact CB-CG 4.4Å; V431-Y437 HydrophobicContact CG1-CD1 4.29Å; V431-Y437 HydrophobicContact CG1-CD2 4.31Å; V431-Y437 HydrophobicContact CG1-CE1 4.44Å; V431-Y437 HydrophobicContact CG1-CE2 4.45Å; V431-Y437 HydrophobicContact CG1-CG 4.24Å
432I98.4Very high98.5Very high40 Ų4056.6 Ų56.621%0.20528%0.282CS..Hα-helixtrans-80.6-43.1177.2-67.8176.3000111.3I304 Q332 K368 A369 I428 K429 S430I304-I432 HydrophobicContact CD1-CD1 4.06Å; I304-I432 HydrophobicContact CG1-CD1 4.14Å; Q332-I432 HydrophobicContact CG-CD1 4.2Å; K368-I432 HydrophobicContact CB-CD1 4.15Å; K368-I432 HydrophobicContact CB-CG1 4.03Å; K368-I432 HydrophobicContact CB-CG2 4.31Å; A369-I432 HydrophobicContact CB-CD1 4.2Å; A369-I432 HydrophobicContact CB-CG1 3.81Å; I428-I432 HydrophobicContact CG2-CD1 3.74Å; I428-I432 HydrophobicContact CG2-CG1 4.49Å; I428-I432 VanDerWaalsContact O-CG1 3.32Å; I428-I432 WeakPolarHBondContact O-CG1 3.3Å; I428-I432 PolarHBondContact O-N 2.76Å; I428-I432 VanDerWaalsContact O-N 3.16Å; K429-I432 PolarHBondContact O-N 2.81Å; S430-I432 VanDerWaalsContact C-N 3.28Å; S430-I432 PolarHBondContact O-N 3.46Å
433N97.9Very high98.6Very high118 Ų11859.1 Ų59.163%0.63129%0.288SS*.Hα-helixtrans-94.9-29.5-168.5-63.2-29.1000113.4K429 S430 K435K429-N433 VanDerWaalsContact O-CB 3.22Å; K429-N433 WeakPolarHBondContact O-CB 3.43Å; K429-N433 VanDerWaalsContact O-CG 3.29Å; K429-N433 PolarHBondContact O-N 3.31Å; K429-N433 PolarHBondContact O-ND2 2.96Å; S430-N433 PolarHBondContact O-N 2.84Å; N433-K435 PolarHBondContact O-N 2.79Å
434N98.4Very high98.6Very high75 Ų7557.5 Ų57.540%0.40128%0.276SS..  trans-82.1112.5176.2-175.7-7.4000109.9S430 S436 Y437S430-N434 VanDerWaalsContact O-CB 3.23Å; S430-N434 WeakPolarHBondContact O-CB 3.24Å; S430-N434 PolarHBondContact O-N 3.3Å; N434-S436 PolarHBondContact ND2-OG 3.48Å; N434-S436 PolarHBondContact O-N 3.46Å; N434-S436 VanDerWaalsContact O-N 3.15Å; N434-S436 PolarHBondContact OD1-N 2.77Å; N434-S436 VanDerWaalsContact OD1-N 3.15Å; N434-S436 PolarHBondContact OD1-OG 3Å; N434-S436 VanDerWaalsContact OD1-OG 3.06Å; N434-Y437 HydrophobicContact CB-CD2 3.9Å; N434-Y437 HydrophobicContact CB-CE2 4.11Å; N434-Y437 PolarHBondContact O-N 3.28Å
435K97.9Very high98.6Very high156 Ų15658 Ų5868%0.67828%0.28SS*.Hα-helixtrans-58.1-29-176-67.3-178.2179.31790113.3N433 Y437 K438 E439N433-K435 PolarHBondContact O-N 2.79Å; K435-Y437 VanDerWaalsContact C-N 3.28Å; K435-Y437 PolarHBondContact O-N 3.43Å; K435-K438 PolarHBondContact O-N 3.49Å; K435-K438 VanDerWaalsContact O-N 3.11Å; K435-E439 WeakPolarHBondContact O-CG 3.37Å; K435-E439 PolarHBondContact O-N 3.25Å
436S98.6Very high98.6Very high43 Ų4363.2 Ų63.230%0.30130%0.304SS..Hα-helixtrans-58.7-38.4-177.567.80000112.5N434 K438 E439 N440N434-S436 PolarHBondContact ND2-OG 3.48Å; N434-S436 PolarHBondContact O-N 3.46Å; N434-S436 VanDerWaalsContact O-N 3.15Å; N434-S436 PolarHBondContact OD1-N 2.77Å; N434-S436 VanDerWaalsContact OD1-N 3.15Å; N434-S436 PolarHBondContact OD1-OG 3Å; N434-S436 VanDerWaalsContact OD1-OG 3.06Å; S436-K438 PolarHBondContact O-N 3.25Å; S436-E439 PolarHBondContact O-N 2.89Å; S436-N440 VanDerWaalsContact O-CB 3.24Å; S436-N440 WeakPolarHBondContact O-CB 3.31Å; S436-N440 PolarHBondContact O-N 3.15Å; S436-N440 PolarHBondContact O-ND2 3.43Å; S436-N440 VanDerWaalsContact O-ND2 3.08Å
437Y98.8Very high98.5Very high42 Ų4262.9 Ų62.917%0.16530%0.302CS..Hα-helixtrans-62.8-44.8177.4-69-73.7000111.9G409 V412 S430 V431 N434 K435 V441G409-Y437 WeakPolarHBondContact O-CA 3.48Å; G409-Y437 VanDerWaalsContact O-CD1 3.23Å; G409-Y437 WeakPolarHBondContact O-CD1 3.42Å; V412-Y437 HydrophobicContact CG2-CE1 3.83Å; V412-Y437 HydrophobicContact CG2-CE2 4.37Å; V412-Y437 VanDerWaalsContact CG2-OH 3.23Å; V412-Y437 WeakPolarHBondContact CG2-OH 3.37Å; S430-Y437 WeakPolarHBondContact OG-CE2 3.37Å; V431-Y437 HydrophobicContact CB-CD2 4.43Å; V431-Y437 HydrophobicContact CB-CG 4.4Å; V431-Y437 HydrophobicContact CG1-CD1 4.29Å; V431-Y437 HydrophobicContact CG1-CD2 4.31Å; V431-Y437 HydrophobicContact CG1-CE1 4.44Å; V431-Y437 HydrophobicContact CG1-CE2 4.45Å; V431-Y437 HydrophobicContact CG1-CG 4.24Å; N434-Y437 HydrophobicContact CB-CD2 3.9Å; N434-Y437 HydrophobicContact CB-CE2 4.11Å; N434-Y437 PolarHBondContact O-N 3.28Å; K435-Y437 VanDerWaalsContact C-N 3.28Å; K435-Y437 PolarHBondContact O-N 3.43Å; Y437-V441 WeakPolarHBondContact O-CG1 3.42Å; Y437-V441 PolarHBondContact O-N 3Å
438K98.4Very high98.5Very high80 Ų8062.9 Ų62.935%0.34830%0.301SS..Hα-helixtrans-67-44.4177.7-177.161177.6-1790111.1G386 K435 S436 V441 M442G386-K438 PolarHBondContact O-NZ 3.36Å; K435-K438 PolarHBondContact O-N 3.49Å; K435-K438 VanDerWaalsContact O-N 3.11Å; S436-K438 PolarHBondContact O-N 3.25Å; K438-V441 HydrophobicContact CD-CG1 4.35Å; K438-V441 WeakPolarHBondContact O-CG1 3.35Å; K438-M442 HydrophobicContact CD-CG 4.05Å; K438-M442 HydrophobicContact CG-CG 4.32Å; K438-M442 VanDerWaalsContact O-CB 3.31Å; K438-M442 WeakPolarHBondContact O-CB 3.45Å; K438-M442 WeakPolarHBondContact O-CG 3.5Å; K438-M442 PolarHBondContact O-N 3.02Å
439E98.8Very high98.4Very high123 Ų12367.4 Ų67.458%0.57532%0.322SS*.Hα-helixtrans-61.6-45.1178.3-72.3168.6-17800111.6K435 S436 M442 R443K435-E439 WeakPolarHBondContact O-CG 3.37Å; K435-E439 PolarHBondContact O-N 3.25Å; S436-E439 PolarHBondContact O-N 2.89Å; E439-M442 PolarHBondContact O-N 3.35Å; E439-R443 PolarHBondContact O-N 3.49Å
440N98.8Very high98.3Very high43 Ų4369.6 Ų69.623%0.2334%0.337CS..Hα-helixtrans-62.6-50.2178-74.2-29.4000111.6G409 S436 M442 R443 L444G409-N440 WeakPolarHBondContact O-CB 2.87Å; G409-N440 PolarHBondContact O-ND2 3.21Å; S436-N440 VanDerWaalsContact O-CB 3.24Å; S436-N440 WeakPolarHBondContact O-CB 3.31Å; S436-N440 PolarHBondContact O-N 3.15Å; S436-N440 PolarHBondContact O-ND2 3.43Å; S436-N440 VanDerWaalsContact O-ND2 3.08Å; N440-M442 VanDerWaalsContact C-N 3.31Å; N440-M442 PolarHBondContact O-N 2.84Å; N440-R443 VanDerWaalsContact O-CB 3.29Å; N440-R443 WeakPolarHBondContact O-CB 3.4Å; N440-R443 PolarHBondContact O-N 2.97Å; N440-R443 VanDerWaalsContact O-N 3.12Å; N440-L444 WeakPolarHBondContact O-CG 3.26Å; N440-L444 PolarHBondContact O-N 3.35Å
441V98.8Very high98.1Very high0 Ų068.9 Ų68.90%033%0.328CS..Hα-helixtrans-67.6-32-179.975.20000112.3G386 P388 A410 Y437 K438 R443 L444 S445G386-V441 VanDerWaalsContact C-CG1 3.45Å; G386-V441 VanDerWaalsContact O-CG1 3.22Å; G386-V441 WeakPolarHBondContact O-CG1 3.33Å; P388-V441 HydrophobicContact CB-CG1 4.31Å; A410-V441 HydrophobicContact CB-CB 4.01Å; A410-V441 HydrophobicContact CB-CG2 4.37Å; Y437-V441 WeakPolarHBondContact O-CG1 3.42Å; Y437-V441 PolarHBondContact O-N 3Å; K438-V441 HydrophobicContact CD-CG1 4.35Å; K438-V441 WeakPolarHBondContact O-CG1 3.35Å; V441-R443 VanDerWaalsContact C-N 3.32Å; V441-L444 PolarHBondContact O-N 3.43Å; V441-S445 WeakPolarHBondContact O-CB 3.3Å; V441-S445 PolarHBondContact O-N 2.89Å
442M98.7Very high97.9Very high88 Ų8875.2 Ų75.243%0.43337%0.369SS..Hα-helixtrans-66.8-35.1172.5-72.4-60.5-5600111.6K438 E439 N440 S445 K446K438-M442 HydrophobicContact CD-CG 4.05Å; K438-M442 HydrophobicContact CG-CG 4.32Å; K438-M442 VanDerWaalsContact O-CB 3.31Å; K438-M442 WeakPolarHBondContact O-CB 3.45Å; K438-M442 WeakPolarHBondContact O-CG 3.5Å; K438-M442 PolarHBondContact O-N 3.02Å; E439-M442 PolarHBondContact O-N 3.35Å; N440-M442 VanDerWaalsContact C-N 3.31Å; N440-M442 PolarHBondContact O-N 2.84Å; M442-S445 WeakPolarHBondContact O-CB 3.18Å; M442-S445 PolarHBondContact O-N 3.22Å; M442-K446 PolarHBondContact O-N 3.09Å
443R98.8Very high97.8Very high144 Ų14477 Ų7754%0.54338%0.377SS..Hα-helixtrans-61.6-44.9170.6-171.1-175.677-177.72111E439 N440 V441 K446 I447E439-R443 PolarHBondContact O-N 3.49Å; N440-R443 VanDerWaalsContact O-CB 3.29Å; N440-R443 WeakPolarHBondContact O-CB 3.4Å; N440-R443 PolarHBondContact O-N 2.97Å; N440-R443 VanDerWaalsContact O-N 3.12Å; V441-R443 VanDerWaalsContact C-N 3.32Å; R443-K446 PolarHBondContact O-N 3.13Å; R443-I447 HydrophobicContact CG-CD1 4.42Å; R443-I447 WeakPolarHBondContact O-CG1 3.43Å; R443-I447 PolarHBondContact O-N 3.11Å; R443-I447 VanDerWaalsContact O-N 3.11Å
444L98.7Very high97.7Very high3 Ų373.6 Ų73.62%0.01636%0.363CS..Hα-helixtrans-64-41.9176.3-56.5-177.2000111.6D262 I383 M405 K408 A410 N440 V441 K446 I447 H448D262-L444 HydrophobicContact CB-CB 4.44Å; D262-L444 WeakPolarHBondContact O-CD2 3.42Å; I383-L444 HydrophobicContact CG2-CB 3.99Å; M405-L444 HydrophobicContact CE-CD1 3.73Å; K408-L444 HydrophobicContact CB-CD1 4.07Å; K408-L444 HydrophobicContact CD-CD1 3.84Å; K408-L444 HydrophobicContact CD-CD2 3.93Å; A410-L444 HydrophobicContact CB-CD1 4.1Å; N440-L444 WeakPolarHBondContact O-CG 3.26Å; N440-L444 PolarHBondContact O-N 3.35Å; V441-L444 PolarHBondContact O-N 3.43Å; L444-K446 VanDerWaalsContact C-N 3.33Å; L444-K446 PolarHBondContact O-N 3.1Å; L444-I447 PolarHBondContact O-N 3.26Å; L444-H448 WeakPolarHBondContact O-CB 3.43Å; L444-H448 PolarHBondContact O-N 2.85Å
445S98.6Very high97.6Very high11 Ų1170.8 Ų70.88%0.07735%0.349CS..Hα-helixtrans-57.2-45.9174.1-1740000111.5I383 Y384 V441 M442 I447 H448 H449I383-S445 VanDerWaalsContact O-CA 3.22Å; I383-S445 WeakPolarHBondContact O-CA 3.42Å; I383-S445 WeakPolarHBondContact O-CB 3.45Å; I383-S445 PolarHBondContact O-OG 3.33Å; I383-S445 VanDerWaalsContact O-OG 3.13Å; Y384-S445 PolarHBondContact O-OG 2.89Å; V441-S445 WeakPolarHBondContact O-CB 3.3Å; V441-S445 PolarHBondContact O-N 2.89Å; M442-S445 WeakPolarHBondContact O-CB 3.18Å; M442-S445 PolarHBondContact O-N 3.22Å; S445-I447 VanDerWaalsContact C-N 3.34Å; S445-I447 PolarHBondContact O-N 3.46Å; S445-H448 VanDerWaalsContact O-CB 3.28Å; S445-H448 WeakPolarHBondContact O-CB 3.35Å; S445-H448 PolarHBondContact O-N 3.08Å; S445-H448 VanDerWaalsContact O-N 3.1Å; S445-H449 PolarHBondContact O-CD2 3.24Å; S445-H449 PolarHBondContact O-N 3.33Å
446K98.4Very high97.5Very high155 Ų15566.4 Ų66.467%0.67433%0.328SS*.Hα-helixtrans-58.3-46.6175.9-173.5-179.6177.1-176.60111.4M442 R443 L444 H448 H449 D450M442-K446 PolarHBondContact O-N 3.09Å; R443-K446 PolarHBondContact O-N 3.13Å; L444-K446 VanDerWaalsContact C-N 3.33Å; L444-K446 PolarHBondContact O-N 3.1Å; K446-H448 VanDerWaalsContact C-N 3.29Å; K446-H448 PolarHBondContact O-N 2.87Å; K446-H449 PolarHBondContact O-N 3.4Å; K446-D450 WeakPolarHBondContact O-CB 3.43Å; K446-D450 PolarHBondContact O-N 3.49Å
447I97.8Very high97.4Very high67 Ų6767.1 Ų67.134%0.34433%0.329SS..Hα-helixtrans-62.5-37.5176.2-64.4164.4000111.2D262 R443 L444 S445 H449 D450D262-I447 HydrophobicContact CB-CB 4.31Å; D262-I447 HydrophobicContact CB-CG2 4.04Å; R443-I447 HydrophobicContact CG-CD1 4.42Å; R443-I447 WeakPolarHBondContact O-CG1 3.43Å; R443-I447 PolarHBondContact O-N 3.11Å; R443-I447 VanDerWaalsContact O-N 3.11Å; L444-I447 PolarHBondContact O-N 3.26Å; S445-I447 VanDerWaalsContact C-N 3.34Å; S445-I447 PolarHBondContact O-N 3.46Å; I447-H449 PolarHBondContact O-N 3.45Å; I447-D450 PolarHBondContact O-N 3.33Å
448H97.8Very high97.3Very high6 Ų667 Ų673%0.02833%0.329CS..Hα-helixtrans-60.8-44.8178.1-172.280.8000112.1D262 Y380 I383 Y384 L444 S445 K446 R451D262-H448 WeakPolarHBondContact OD2-CA 3.37Å; D262-H448 WeakPolarHBondContact OD2-CB 3.24Å; D262-H448 IonicContact OD2-CE1 3.7Å; D262-H448 IonicContact OD2-CG 2.79Å; D262-H448 VanDerWaalsContact OD2-CG 3.27Å; D262-H448 IonicContact OD2-ND1 2.76Å; D262-H448 PolarHBondContact OD2-ND1 3.48Å; Y380-H448 AromaticContact CD1-CE1 3.86Å; Y380-H448 AromaticContact CD1-ND1 3.95Å; I383-H448 HydrophobicContact CG2-CB 3.88Å; Y384-H448 AromaticContact CD2-CD2 3.51Å; Y384-H448 AromaticContact CD2-NE2 3.49Å; Y384-H448 WeakPolarHBondContact CD2-NE2 3.47Å; L444-H448 WeakPolarHBondContact O-CB 3.43Å; L444-H448 PolarHBondContact O-N 2.85Å; S445-H448 VanDerWaalsContact O-CB 3.28Å; S445-H448 WeakPolarHBondContact O-CB 3.35Å; S445-H448 PolarHBondContact O-N 3.08Å; S445-H448 VanDerWaalsContact O-N 3.1Å; K446-H448 VanDerWaalsContact C-N 3.29Å; K446-H448 PolarHBondContact O-N 2.87Å; H448-R451 PolarHBondContact CE1-NH2 2.82Å; H448-R451 PolarHBondContact ND1-NH2 3.29Å; H448-R451 WeakPolarHBondContact O-CD 3.44Å; H448-R451 WeakPolarHBondContact O-CG 3.31Å; H448-R451 PolarHBondContact O-NE 2.89Å
449H97.1Very high97.3Very high95 Ų9563.2 Ų63.244%0.4431%0.313SS..Hα-helixtrans-82.1-24.9-178.7-68.6-69.6000113.5Y384 S445 K446 I447 R451Y384-H449 AromaticContact CD1-CE1 3.97Å; Y384-H449 AromaticContact CD2-CE1 3.58Å; Y384-H449 AromaticContact CE1-CE1 3.76Å; Y384-H449 AromaticContact CE2-CE1 3.33Å; Y384-H449 WeakPolarHBondContact CE2-CE1 3.43Å; Y384-H449 AromaticContact CE2-ND1 3.96Å; Y384-H449 AromaticContact CG-CE1 3.89Å; Y384-H449 AromaticContact CZ-CE1 3.43Å; Y384-H449 VanDerWaalsContact CZ-CE1 3.43Å; Y384-H449 PolarHBondContact O-NE2 2.84Å; S445-H449 PolarHBondContact O-CD2 3.24Å; S445-H449 PolarHBondContact O-N 3.33Å; K446-H449 PolarHBondContact O-N 3.4Å; I447-H449 PolarHBondContact O-N 3.45Å; H449-R451 PolarHBondContact O-N 3.26Å
450D96.8Very high97.3Very high129 Ų12957.3 Ų57.369%0.6929%0.286SS*.  trans-80.468.2-179.7-165.218.4000111.4K446 I447K446-D450 WeakPolarHBondContact O-CB 3.43Å; K446-D450 PolarHBondContact O-N 3.49Å; I447-D450 PolarHBondContact O-N 3.33Å
451R94.6Very high97.2Very high27 Ų2758.8 Ų58.810%0.10229%0.29CS..  trans-129.9147179.9-60.2-175.3-166.5-170.78.6110.2F260 D262 G277 H448 H449 M453F260-R451 VanDerWaalsContact CB-NH2 3.27Å; F260-R451 HydrophobicContact CE1-CG 4.13Å; F260-R451 VanDerWaalsContact CE1-NE 3.27Å; F260-R451 VanDerWaalsContact CG-NH1 3.34Å; F260-R451 HydrophobicContact CZ-CG 4.03Å; D262-R451 IonicContact OD1-NH2 3.85Å; D262-R451 IonicContact OD2-NH2 3.66Å; D262-R451 PolarHBondContact OD2-NH2 3.4Å; G277-R451 PolarHBondContact O-NH1 2.8Å; G277-R451 PolarHBondContact O-NH2 2.73Å; H448-R451 PolarHBondContact CE1-NH2 2.82Å; H448-R451 PolarHBondContact ND1-NH2 3.29Å; H448-R451 WeakPolarHBondContact O-CD 3.44Å; H448-R451 WeakPolarHBondContact O-CG 3.31Å; H448-R451 PolarHBondContact O-NE 2.89Å; H449-R451 PolarHBondContact O-N 3.26Å; R451-M453 WeakPolarHBondContact CB-O 3.11Å; R451-M453 PolarHBondContact O-N 3.29Å
452P94.4Very high97.2Very high135 Ų13560.4 Ų60.488%0.87730%0.296SS*.SBendtrans-65.7-27.9179.226.7-34.9000112.8
453M95.4Very high97.2Very high76 Ų7656.2 Ų56.237%0.37428%0.276SS..SBendtrans-136.4152.1176.6-69.9-179.159.900109.6R451 D457 E458 F461R451-M453 WeakPolarHBondContact CB-O 3.11Å; R451-M453 PolarHBondContact O-N 3.29Å; M453-D457 HydrophobicContact CE-CB 3.82Å; M453-D457 WeakPolarHBondContact CE-O 3.47Å; M453-E458 HydrophobicContact CB-CB 4.45Å; M453-F461 HydrophobicContact CE-CB 4Å
454S95.4Very high97.2Very high48 Ų4850.6 Ų50.634%0.33626%0.256SS..  trans-63147.9170.583.70000109.6R456 D457 E458S454-R456 PolarHBondContact O-N 3.37Å; S454-R456 VanDerWaalsContact O-N 3.12Å; S454-D457 PolarHBondContact O-N 3.17Å; S454-D457 VanDerWaalsContact O-N 3.09Å; S454-D457 WeakPolarHBondContact OG-CB 3.23Å; S454-D457 PolarHBondContact OG-N 3.27Å; S454-D457 PolarHBondContact OG-OD2 2.96Å; S454-E458 PolarHBondContact O-N 3.39Å
455P96.4Very high97.2Very high15 Ų1552 Ų5210%0.09726%0.262CS..Hα-helixtrans-56.9-33.2179.9-24.633.9000112.4G277 I279 A459G277-P455 WeakPolarHBondContact O-CG 3.38Å; I279-P455 HydrophobicContact CG2-CB 3.88Å; I279-P455 WeakPolarHBondContact CG2-O 3.49Å; P455-A459 PolarHBondContact O-N 3.25Å; P455-A459 VanDerWaalsContact O-N 3.1Å
456R95.9Very high97.1Very high64 Ų6451.5 Ų51.524%0.24226%0.258CS..Hα-helixtrans-69.6-47.4177.2-167.1-175.3-54.2178.10.1112.1T43 I279 S454 E458 A459 V460T43-R456 WeakPolarHBondContact OG1-CD 3.49Å; I279-R456 PolarHBondContact O-NE 3.3Å; S454-R456 PolarHBondContact O-N 3.37Å; S454-R456 VanDerWaalsContact O-N 3.12Å; R456-E458 VanDerWaalsContact C-N 3.28Å; R456-E458 PolarHBondContact O-N 2.82Å; R456-A459 PolarHBondContact O-N 3.36Å; R456-V460 VanDerWaalsContact O-CG2 3.32Å; R456-V460 WeakPolarHBondContact O-CG2 3.2Å; R456-V460 PolarHBondContact O-N 3.49Å
457D96.6Very high97.1Very high58 Ų5845.3 Ų45.331%0.3123%0.232SC..Hα-helixtrans-65.9-33.8178.5-69.1-50.8000111.8R47 M453 S454 F461R47-D457 IonicContact CZ-OD1 2.66Å; R47-D457 IonicContact NH2-OD1 3.83Å; R47-D457 PolarHBondContact NH2-OD1 3.32Å; M453-D457 HydrophobicContact CE-CB 3.82Å; M453-D457 WeakPolarHBondContact CE-O 3.47Å; S454-D457 PolarHBondContact O-N 3.17Å; S454-D457 VanDerWaalsContact O-N 3.09Å; S454-D457 WeakPolarHBondContact OG-CB 3.23Å; S454-D457 PolarHBondContact OG-N 3.27Å; S454-D457 PolarHBondContact OG-OD2 2.96Å; D457-F461 WeakPolarHBondContact O-CB 3.32Å; D457-F461 PolarHBondContact O-N 2.95Å
458E97.6Very high97Very high39 Ų3948.7 Ų48.718%0.18224%0.24CC..Hα-helixtrans-65-47174.2-177.9169.2-174.500111.3V276 M453 S454 R456 V460 F461 W462V276-E458 HydrophobicContact CG1-CB 4.18Å; V276-E458 HydrophobicContact CG1-CG 3.99Å; M453-E458 HydrophobicContact CB-CB 4.45Å; S454-E458 PolarHBondContact O-N 3.39Å; R456-E458 VanDerWaalsContact C-N 3.28Å; R456-E458 PolarHBondContact O-N 2.82Å; E458-V460 VanDerWaalsContact C-N 3.35Å; E458-V460 PolarHBondContact O-N 3.08Å; E458-F461 PolarHBondContact O-N 3.38Å; E458-W462 PolarHBondContact O-N 3.26Å
459A98.2Very high97Very high1 Ų152.3 Ų52.31%0.00826%0.26CS..Hα-helixtrans-56-49.6175.100000111.7V40 L256 V276 I279 P455 R456 W462 I463V40-A459 HydrophobicContact CG1-CB 4.38Å; V40-A459 HydrophobicContact CG2-CB 4.28Å; L256-A459 HydrophobicContact CD1-CB 3.89Å; V276-A459 HydrophobicContact CB-CB 4.46Å; V276-A459 HydrophobicContact CG1-CB 4.16Å; I279-A459 HydrophobicContact CG2-CB 4.3Å; P455-A459 PolarHBondContact O-N 3.25Å; P455-A459 VanDerWaalsContact O-N 3.1Å; R456-A459 PolarHBondContact O-N 3.36Å; A459-W462 PolarHBondContact O-N 3.45Å; A459-I463 WeakPolarHBondContact O-CG1 3.36Å; A459-I463 PolarHBondContact O-N 3.16Å; A459-I463 VanDerWaalsContact O-N 3.08Å
460V98.1Very high96.9Very high0 Ų056.9 Ų56.90%028%0.278CS..Hα-helixtrans-63.8-42.8179.2176.20000111.3V40 T43 L44 R456 E458 W462 I463 E464V40-V460 HydrophobicContact CG1-CG2 3.98Å; T43-V460 HydrophobicContact CG2-CG2 3.84Å; L44-V460 HydrophobicContact CD2-CG1 3.73Å; L44-V460 HydrophobicContact CD2-CG2 4.49Å; L44-V460 HydrophobicContact CG-CG1 4.3Å; L44-V460 HydrophobicContact CG-CG2 4.28Å; R456-V460 VanDerWaalsContact O-CG2 3.32Å; R456-V460 WeakPolarHBondContact O-CG2 3.2Å; R456-V460 PolarHBondContact O-N 3.49Å; E458-V460 VanDerWaalsContact C-N 3.35Å; E458-V460 PolarHBondContact O-N 3.08Å; V460-W462 VanDerWaalsContact C-N 3.31Å; V460-W462 PolarHBondContact O-N 2.83Å; V460-I463 PolarHBondContact O-N 2.89Å; V460-E464 HydrophobicContact CG1-CG 4.34Å; V460-E464 WeakPolarHBondContact CG1-OE1 3.34Å; V460-E464 WeakPolarHBondContact O-CG 3.4Å; V460-E464 PolarHBondContact O-N 3.13Å
461F98Very high96.9Very high74 Ų7450.9 Ų50.933%0.32525%0.247SC..Hα-helixtrans-56.2-45.1176.8169.4-92.9000111.9M453 D457 E458 E464 F465M453-F461 HydrophobicContact CE-CB 4Å; D457-F461 WeakPolarHBondContact O-CB 3.32Å; D457-F461 PolarHBondContact O-N 2.95Å; E458-F461 PolarHBondContact O-N 3.38Å; F461-E464 PolarHBondContact O-N 3.29Å; F461-F465 HydrophobicContact CE1-CB 4.45Å; F461-F465 HydrophobicContact CE1-CD2 4.48Å; F461-F465 HydrophobicContact CZ-CD2 4.35Å; F461-F465 VanDerWaalsContact O-CB 3.23Å; F461-F465 WeakPolarHBondContact O-CB 3.44Å; F461-F465 PolarHBondContact O-N 3.06Å
462W98.4Very high97Very high34 Ų3449.7 Ų49.713%0.12924%0.243CC..Hα-helixtrans-73.1-31.1-179-75.5109.7000113.2I254 L256 K274 E458 A459 V460 F465 T466 L475I254-W462 HydrophobicContact CD1-CD2 4.41Å; I254-W462 HydrophobicContact CD1-CE3 3.64Å; I254-W462 HydrophobicContact CD1-CZ3 4.1Å; I254-W462 HydrophobicContact CG1-CE3 4.28Å; I254-W462 HydrophobicContact CG2-CB 4.11Å; L256-W462 HydrophobicContact CD2-CB 3.98Å; L256-W462 HydrophobicContact CD2-CG 4.49Å; K274-W462 HydrophobicContact CB-CG 4.48Å; K274-W462 HydrophobicContact CD-CD2 4Å; K274-W462 HydrophobicContact CD-CG 4.39Å; K274-W462 HydrophobicContact CD-CH2 4.41Å; K274-W462 HydrophobicContact CD-CZ2 3.65Å; K274-W462 VanDerWaalsContact CE-CH2 3.42Å; K274-W462 HydrophobicContact CG-CD2 3.8Å; K274-W462 HydrophobicContact CG-CG 3.79Å; K274-W462 HydrophobicContact CG-CZ2 4.4Å; E458-W462 PolarHBondContact O-N 3.26Å; A459-W462 PolarHBondContact O-N 3.45Å; V460-W462 VanDerWaalsContact C-N 3.31Å; V460-W462 PolarHBondContact O-N 2.83Å; W462-F465 HydrophobicContact CE3-CB 4.12Å; W462-F465 AromaticContact CE3-CD1 3.79Å; W462-F465 HydrophobicContact CE3-CD1 3.79Å; W462-F465 HydrophobicContact CE3-CE1 4.37Å; W462-F465 AromaticContact CE3-CG 3.91Å; W462-F465 HydrophobicContact CE3-CG 3.91Å; W462-F465 AromaticContact CZ3-CD1 3.77Å; W462-F465 HydrophobicContact CZ3-CD1 3.77Å; W462-F465 HydrophobicContact CZ3-CD2 4.25Å; W462-F465 AromaticContact CZ3-CE1 3.92Å; W462-F465 HydrophobicContact CZ3-CE1 3.92Å; W462-F465 HydrophobicContact CZ3-CE2 4.37Å; W462-F465 AromaticContact CZ3-CG 3.95Å; W462-F465 HydrophobicContact CZ3-CG 3.95Å; W462-F465 HydrophobicContact CZ3-CZ 4.21Å; W462-F465 PolarHBondContact O-N 2.88Å; W462-T466 PolarHBondContact O-N 3.19Å; W462-T466 PolarHBondContact O-OG1 3.46Å; W462-L475 HydrophobicContact CH2-CD1 4.38Å; W462-L475 HydrophobicContact CZ3-CD1 3.81Å
463I98.6Very high97Very high0 Ų051.9 Ų51.90%024%0.239CC..Hα-helixtrans-63.3-49.2170.1-67.4166.3000109.9I24 V40 L44 V146 F148 V168 L256 A459 V460 F465 T466 M467I24-I463 HydrophobicContact CD1-CG2 4.18Å; V40-I463 HydrophobicContact CG1-CD1 3.79Å; L44-I463 HydrophobicContact CD1-CD1 4.06Å; L44-I463 HydrophobicContact CD1-CG2 4.42Å; L44-I463 HydrophobicContact CD2-CG2 4.08Å; V146-I463 HydrophobicContact CG1-CG2 4.18Å; F148-I463 HydrophobicContact CD1-CD1 4.31Å; F148-I463 HydrophobicContact CD2-CD1 4.03Å; F148-I463 HydrophobicContact CD2-CG1 4.45Å; F148-I463 HydrophobicContact CE1-CD1 4.31Å; F148-I463 HydrophobicContact CE2-CD1 4.06Å; F148-I463 HydrophobicContact CG-CD1 4.17Å; F148-I463 HydrophobicContact CZ-CD1 4.19Å; V168-I463 HydrophobicContact CB-CG1 4.45Å; V168-I463 HydrophobicContact CG1-CG1 3.97Å; L256-I463 HydrophobicContact CD1-CD1 4.23Å; L256-I463 HydrophobicContact CD1-CG1 4.19Å; A459-I463 WeakPolarHBondContact O-CG1 3.36Å; A459-I463 PolarHBondContact O-N 3.16Å; A459-I463 VanDerWaalsContact O-N 3.08Å; V460-I463 PolarHBondContact O-N 2.89Å; I463-F465 VanDerWaalsContact C-N 3.32Å; I463-F465 PolarHBondContact O-N 3.22Å; I463-T466 PolarHBondContact O-N 2.75Å; I463-M467 HydrophobicContact CG2-CE 4.25Å; I463-M467 PolarHBondContact O-N 3.18Å; I463-M467 VanDerWaalsContact O-N 3.12Å
464E98.2Very high96.9Very high25 Ų2554.2 Ų54.212%0.11725%0.249CC..Hα-helixtrans-64.5-36.2176.2-63.2170.8-170.600113R47 H49 V460 F461 T466 M467 R468R47-E464 WeakPolarHBondContact CD-OE1 3.44Å; R47-E464 IonicContact CZ-OE1 3.96Å; R47-E464 IonicContact NE-OE1 3.79Å; R47-E464 IonicContact NH1-OE1 3.86Å; R47-E464 PolarHBondContact NH1-OE1 3.47Å; R47-E464 IonicContact NH1-OE2 3.04Å; H49-E464 IonicContact NE2-OE1 3.8Å; V460-E464 HydrophobicContact CG1-CG 4.34Å; V460-E464 WeakPolarHBondContact CG1-OE1 3.34Å; V460-E464 WeakPolarHBondContact O-CG 3.4Å; V460-E464 PolarHBondContact O-N 3.13Å; F461-E464 PolarHBondContact O-N 3.29Å; E464-T466 VanDerWaalsContact C-N 3.33Å; E464-M467 HydrophobicContact CB-CE 4.19Å; E464-M467 HydrophobicContact CG-CE 4.07Å; E464-M467 PolarHBondContact O-N 2.81Å; E464-R468 WeakPolarHBondContact O-CB 3.45Å; E464-R468 VanDerWaalsContact O-CG 3.31Å; E464-R468 WeakPolarHBondContact O-CG 3.31Å; E464-R468 PolarHBondContact O-N 2.82Å; E464-R468 IonicContact OE2-CZ 2.72Å; E464-R468 IonicContact OE2-NH1 2.9Å; E464-R468 PolarHBondContact OE2-NH1 2.95Å
465F98.1Very high97Very high33 Ų3353.3 Ų53.315%0.14524%0.24CC..Hα-helixtrans-58.8-47.6175.4176.4-86.2000110.5F461 W462 I463 M467 R468 N469 A472 H474 L475F461-F465 HydrophobicContact CE1-CB 4.45Å; F461-F465 HydrophobicContact CE1-CD2 4.48Å; F461-F465 HydrophobicContact CZ-CD2 4.35Å; F461-F465 VanDerWaalsContact O-CB 3.23Å; F461-F465 WeakPolarHBondContact O-CB 3.44Å; F461-F465 PolarHBondContact O-N 3.06Å; W462-F465 HydrophobicContact CE3-CB 4.12Å; W462-F465 AromaticContact CE3-CD1 3.79Å; W462-F465 HydrophobicContact CE3-CD1 3.79Å; W462-F465 HydrophobicContact CE3-CE1 4.37Å; W462-F465 AromaticContact CE3-CG 3.91Å; W462-F465 HydrophobicContact CE3-CG 3.91Å; W462-F465 AromaticContact CZ3-CD1 3.77Å; W462-F465 HydrophobicContact CZ3-CD1 3.77Å; W462-F465 HydrophobicContact CZ3-CD2 4.25Å; W462-F465 AromaticContact CZ3-CE1 3.92Å; W462-F465 HydrophobicContact CZ3-CE1 3.92Å; W462-F465 HydrophobicContact CZ3-CE2 4.37Å; W462-F465 AromaticContact CZ3-CG 3.95Å; W462-F465 HydrophobicContact CZ3-CG 3.95Å; W462-F465 HydrophobicContact CZ3-CZ 4.21Å; W462-F465 PolarHBondContact O-N 2.88Å; I463-F465 VanDerWaalsContact C-N 3.32Å; I463-F465 PolarHBondContact O-N 3.22Å; F465-M467 VanDerWaalsContact C-N 3.34Å; F465-M467 PolarHBondContact O-N 3.07Å; F465-R468 PolarHBondContact O-N 3.32Å; F465-N469 WeakPolarHBondContact CE2-ND2 3.22Å; F465-N469 WeakPolarHBondContact O-CB 3.31Å; F465-N469 PolarHBondContact O-N 3.48Å; F465-N469 PolarHBondContact O-ND2 3.28Å; F465-A472 HydrophobicContact CE1-CB 4.26Å; F465-H474 AromaticContact CE1-CE1 3.87Å; F465-H474 AromaticContact CE1-NE2 3.93Å; F465-H474 AromaticContact CZ-CE1 3.67Å; F465-H474 AromaticContact CZ-NE2 3.46Å; F465-H474 WeakPolarHBondContact CZ-NE2 3.32Å; F465-L475 HydrophobicContact CE1-CD1 4.14Å
466T98.3Very high96.8Very high0 Ų056.3 Ų56.30%025%0.249CC..Hα-helixtrans-60.8-43.4177.7-62.30000111.4V146 P166 V168 D253 I254 W462 I463 E464 N469 K470 G471V146-T466 HydrophobicContact CG2-CG2 4.12Å; P166-T466 HydrophobicContact CB-CG2 3.37Å; P166-T466 HydrophobicContact CG-CG2 4.29Å; V168-T466 HydrophobicContact CG2-CG2 3.88Å; D253-T466 HydrophobicContact CB-CG2 3.89Å; I254-T466 WeakPolarHBondContact CG1-OG1 3.28Å; W462-T466 PolarHBondContact O-N 3.19Å; W462-T466 PolarHBondContact O-OG1 3.46Å; I463-T466 PolarHBondContact O-N 2.75Å; E464-T466 VanDerWaalsContact C-N 3.33Å; T466-N469 PolarHBondContact O-N 3.5Å; T466-K470 PolarHBondContact O-N 2.96Å; T466-G471 PolarHBondContact O-N 3.01Å
467M97.2Very high96.7Very high25 Ų2554.9 Ų54.912%0.12325%0.248CC..Hα-helixtrans-61.4-51.2175.5-69-173.9-66.900111.9I24 H49 D145 V146 I463 E464 F465 N469 K470I24-M467 HydrophobicContact CD1-CE 4.14Å; I24-M467 HydrophobicContact CD1-SD 4.23Å; I24-M467 HydrophobicContact CG1-CE 4.46Å; I24-M467 HydrophobicContact CG1-SD 3.9Å; H49-M467 WeakPolarHBondContact CE1-CE 3.14Å; D145-M467 HydrophobicContact CB-CB 4.44Å; D145-M467 HydrophobicContact CB-CG 3.96Å; D145-M467 HydrophobicContact CB-SD 4.03Å; V146-M467 HydrophobicContact CB-CG 3.75Å; V146-M467 HydrophobicContact CG1-CG 3.47Å; V146-M467 VanDerWaalsContact CG1-CG 3.47Å; V146-M467 HydrophobicContact CG1-SD 3.65Å; I463-M467 HydrophobicContact CG2-CE 4.25Å; I463-M467 PolarHBondContact O-N 3.18Å; I463-M467 VanDerWaalsContact O-N 3.12Å; E464-M467 HydrophobicContact CB-CE 4.19Å; E464-M467 HydrophobicContact CG-CE 4.07Å; E464-M467 PolarHBondContact O-N 2.81Å; F465-M467 VanDerWaalsContact C-N 3.34Å; F465-M467 PolarHBondContact O-N 3.07Å; M467-N469 PolarHBondContact O-N 2.86Å; M467-K470 PolarHBondContact O-N 3.09Å
468R96.4Very high96.5Very high139 Ų13958.4 Ų58.453%0.52526%0.262SS..Hα-helixtrans-59.8-33.7-177.9-73.8-174.6-62.3-100.9-3.1112.9E464 F465E464-R468 WeakPolarHBondContact O-CB 3.45Å; E464-R468 VanDerWaalsContact O-CG 3.31Å; E464-R468 WeakPolarHBondContact O-CG 3.31Å; E464-R468 PolarHBondContact O-N 2.82Å; E464-R468 IonicContact OE2-CZ 2.72Å; E464-R468 IonicContact OE2-NH1 2.9Å; E464-R468 PolarHBondContact OE2-NH1 2.95Å; F465-R468 PolarHBondContact O-N 3.32Å
469N96.8Very high96.3Very high82 Ų8257.4 Ų57.444%0.43926%0.261SS..Hα-helixtrans-99.53.2-176.3-66.7-79.8000113.7F465 T466 M467 G471F465-N469 WeakPolarHBondContact CE2-ND2 3.22Å; F465-N469 WeakPolarHBondContact O-CB 3.31Å; F465-N469 PolarHBondContact O-N 3.48Å; F465-N469 PolarHBondContact O-ND2 3.28Å; T466-N469 PolarHBondContact O-N 3.5Å; M467-N469 PolarHBondContact O-N 2.86Å; N469-G471 VanDerWaalsContact C-N 3.27Å; N469-G471 VanDerWaalsContact CB-O 3.27Å; N469-G471 WeakPolarHBondContact CB-O 3.4Å; N469-G471 PolarHBondContact O-N 3.38Å
470K95.3Very high96Very high190 Ų19057.9 Ų57.983%0.82626%0.263SS*.THydrogen-bonded Turntrans52.846.4-175.9-55.7-176.6178.3-175.20111.9T466 M467T466-K470 PolarHBondContact O-N 2.96Å; M467-K470 PolarHBondContact O-N 3.09Å
471G96.4Very high95.8Very high4 Ų463.4 Ų63.44%0.04129%0.289CS..SBendtrans111.3-174.5-173.300000113.4D253 T466 N469D253-G471 WeakPolarHBondContact OD1-CA 3.42Å; T466-G471 PolarHBondContact O-N 3.01Å; N469-G471 VanDerWaalsContact C-N 3.27Å; N469-G471 VanDerWaalsContact CB-O 3.27Å; N469-G471 WeakPolarHBondContact CB-O 3.4Å; N469-G471 PolarHBondContact O-N 3.38Å
472A96.9Very high95.6Very high2 Ų263.2 Ų63.22%0.01729%0.291CS..  trans-137.832.6-176.200000112.8D253 I254 F465 H474 L475D253-A472 HydrophobicContact CB-CB 3.88Å; D253-A472 PolarHBondContact OD1-N 3.21Å; I254-A472 HydrophobicContact CD1-CB 4.11Å; I254-A472 HydrophobicContact CG1-CB 4.32Å; F465-A472 HydrophobicContact CE1-CB 4.26Å; A472-H474 PolarHBondContact O-N 3.33Å; A472-L475 HydrophobicContact CB-CD1 4.17Å; A472-L475 HydrophobicContact CB-CG 4.46Å; A472-L475 WeakPolarHBondContact O-CB 3.49Å; A472-L475 PolarHBondContact O-N 3Å
473K93.9Very high95.4Very high181 Ų18164 Ų6479%0.78730%0.299SS*.G310 helixtrans-52.6-30.4-177.6-67.4-175.9179.9178.40114.5L475 R476K473-L475 PolarHBondContact O-N 2.78Å; K473-R476 VanDerWaalsContact O-CB 3.24Å; K473-R476 WeakPolarHBondContact O-CB 3.48Å; K473-R476 PolarHBondContact O-N 2.89Å; K473-R476 VanDerWaalsContact O-N 3.17Å
474H94.9Very high95Very high125 Ų12572.6 Ų72.658%0.57933%0.332SS*.G310 helixtrans-71.3-12.2177.962.1-87.1000114F465 A472F465-H474 AromaticContact CE1-CE1 3.87Å; F465-H474 AromaticContact CE1-NE2 3.93Å; F465-H474 AromaticContact CZ-CE1 3.67Å; F465-H474 AromaticContact CZ-NE2 3.46Å; F465-H474 WeakPolarHBondContact CZ-NE2 3.32Å; A472-H474 PolarHBondContact O-N 3.33Å
475L96.1Very high94.9Very high29 Ų2976 Ų7615%0.15234%0.344CS..G310 helixtrans-94.4-5.3173-58-177.4000112.6I254 P271 N272 W462 F465 A472 K473I254-L475 HydrophobicContact CD1-CD1 3.91Å; P271-L475 HydrophobicContact CB-CB 4.19Å; P271-L475 HydrophobicContact CB-CD2 4.02Å; N272-L475 HydrophobicContact CB-CB 3.88Å; W462-L475 HydrophobicContact CH2-CD1 4.38Å; W462-L475 HydrophobicContact CZ3-CD1 3.81Å; F465-L475 HydrophobicContact CE1-CD1 4.14Å; A472-L475 HydrophobicContact CB-CD1 4.17Å; A472-L475 HydrophobicContact CB-CG 4.46Å; A472-L475 WeakPolarHBondContact O-CB 3.49Å; A472-L475 PolarHBondContact O-N 3Å; K473-L475 PolarHBondContact O-N 2.78Å
476R92.4Very high94.8Very high77 Ų7778.1 Ų78.129%0.29135%0.354SS..  trans-74.8134.2179-177172.7162158.1-15.2110.1R250 N251 K473 H480 E481R250-R476 PolarHBondContact O-NH1 3.14Å; N251-R476 PolarHBondContact OD1-NH1 3.04Å; N251-R476 VanDerWaalsContact OD1-NH1 3.09Å; K473-R476 VanDerWaalsContact O-CB 3.24Å; K473-R476 WeakPolarHBondContact O-CB 3.48Å; K473-R476 PolarHBondContact O-N 2.89Å; K473-R476 VanDerWaalsContact O-N 3.17Å; R476-H480 WeakPolarHBondContact CG-CD2 3.46Å; R476-E481 IonicContact CZ-OE1 3.96Å; R476-E481 IonicContact NE-OE1 2.87Å; R476-E481 IonicContact NH2-OE1 2.66Å; R476-E481 PolarHBondContact NH2-OE1 3.22Å
477V93.7Very high94.6Very high35 Ų3582.4 Ų82.421%0.21237%0.371CS..  trans-78.7152178.3-70.30000112.9Q185 L270 A479 H480Q185-V477 HydrophobicContact CB-CG2 3.97Å; L270-V477 HydrophobicContact CD1-CG1 4.03Å; L270-V477 HydrophobicContact CD1-CG2 3.75Å; L270-V477 HydrophobicContact CD2-CG1 3.53Å; L270-V477 HydrophobicContact CG-CG1 4.24Å; V477-A479 HydrophobicContact CG2-CB 3.92Å; V477-A479 PolarHBondContact O-N 3.23Å; V477-A479 VanDerWaalsContact O-N 3.15Å; V477-H480 PolarHBondContact O-CD2 3.37Å; V477-H480 VanDerWaalsContact O-CD2 3.3Å; V477-H480 PolarHBondContact O-N 2.91Å
478Q93.7Very high94.4Very high131 Ų13186.7 Ų86.761%0.61239%0.391SS*.G310 helixtrans-63.4-19.4176.8-170.360.724.900113.3H480 E481Q478-H480 PolarHBondContact O-N 2.97Å; Q478-E481 PolarHBondContact O-N 2.85Å
479A93.3Very high94.5Very high18 Ų1883 Ų8315%0.14939%0.386CS..G310 helixtrans-53.4-28.4-18000000113.7Q185 V477 E481 L482 Y487Q185-A479 HydrophobicContact CB-CB 4.06Å; Q185-A479 HydrophobicContact CG-CB 4.13Å; V477-A479 HydrophobicContact CG2-CB 3.92Å; V477-A479 PolarHBondContact O-N 3.23Å; V477-A479 VanDerWaalsContact O-N 3.15Å; A479-E481 PolarHBondContact O-N 2.79Å; A479-L482 PolarHBondContact O-N 3.35Å; A479-Y487 HydrophobicContact CB-CD2 3.83Å; A479-Y487 HydrophobicContact CB-CE2 3.66Å
480H91.9Very high94.5Very high11 Ų1182.3 Ų82.35%0.05138%0.382CS..G310 helixtrans-65.3-21.6176.8-67.7-78.3000114.5C183 Q185 R476 V477 Q478C183-H480 PolarHBondContact O-CE1 3.48Å; Q185-H480 WeakPolarHBondContact CG-CE1 3.47Å; Q185-H480 WeakPolarHBondContact CG-ND1 3.3Å; R476-H480 WeakPolarHBondContact CG-CD2 3.46Å; V477-H480 PolarHBondContact O-CD2 3.37Å; V477-H480 VanDerWaalsContact O-CD2 3.3Å; V477-H480 PolarHBondContact O-N 2.91Å; Q478-H480 PolarHBondContact O-N 2.97Å
481E92.8Very high94.6Very high117 Ų11776.5 Ų76.555%0.54736%0.36SS..G310 helixtrans-105.5-2.8-175.6-50.7-52.313700112.7R476 Q478 A479R476-E481 IonicContact CZ-OE1 3.96Å; R476-E481 IonicContact NE-OE1 2.87Å; R476-E481 IonicContact NH2-OE1 2.66Å; R476-E481 PolarHBondContact NH2-OE1 3.22Å; Q478-E481 PolarHBondContact O-N 2.85Å; A479-E481 PolarHBondContact O-N 2.79Å
482L93.7Very high94.7Very high70 Ų7079.9 Ų79.937%0.36638%0.38SS..SBendtrans-89.7146.9178.7-62.3179.8000111.1A479 Q486A479-L482 PolarHBondContact O-N 3.35Å; L482-Q486 HydrophobicContact CB-CB 4.24Å; L482-Q486 HydrophobicContact CD2-CB 4.35Å
483T94.2Very high94.7Very high49 Ų4984.8 Ų84.830%0.30141%0.405SS..  trans-71.1159.2164.466.50000110.3Y485 Q486 Y487T483-Y485 HydrophobicContact CG2-CE1 4.07Å; T483-Y485 PolarHBondContact O-N 3.02Å; T483-Y485 WeakPolarHBondContact OG1-CD1 3.32Å; T483-Y485 WeakPolarHBondContact OG1-CD2 3.24Å; T483-Y485 VanDerWaalsContact OG1-CE1 3.25Å; T483-Y485 WeakPolarHBondContact OG1-CE1 3.45Å; T483-Y485 WeakPolarHBondContact OG1-CE2 3.25Å; T483-Q486 VanDerWaalsContact N-OE1 3.12Å; T483-Q486 PolarHBondContact O-N 2.91Å; T483-Q486 VanDerWaalsContact O-N 3.13Å; T483-Q486 WeakPolarHBondContact OG1-CB 3.28Å; T483-Q486 VanDerWaalsContact OG1-CG 3.29Å; T483-Q486 WeakPolarHBondContact OG1-CG 3.49Å; T483-Q486 PolarHBondContact OG1-N 3.28Å; T483-Q486 PolarHBondContact OG1-OE1 3.12Å; T483-Q486 VanDerWaalsContact OG1-OE1 3.07Å; T483-Y487 WeakPolarHBondContact O-CB 3.41Å; T483-Y487 PolarHBondContact O-N 3.36Å
484W91.9Very high94.9Very high181 Ų18178.4 Ų78.469%0.68639%0.386SS*.Hα-helixtrans-58.1-35-177.669.7-92.5000112.9H488 L490W484-H488 PolarHBondContact O-CD2 3.38Å; W484-H488 PolarHBondContact O-N 2.89Å; W484-L490 HydrophobicContact CE3-CD1 3.99Å; W484-L490 HydrophobicContact CH2-CD1 4.02Å; W484-L490 HydrophobicContact CZ3-CD1 3.29Å
485Y94.4Very high95.1Very high98 Ų9878.5 Ų78.538%0.38439%0.385SS..Hα-helixtrans-77.2-34.1178.857-97.1000112.3T483 H488 S489 L490 D491T483-Y485 HydrophobicContact CG2-CE1 4.07Å; T483-Y485 PolarHBondContact O-N 3.02Å; T483-Y485 WeakPolarHBondContact OG1-CD1 3.32Å; T483-Y485 WeakPolarHBondContact OG1-CD2 3.24Å; T483-Y485 VanDerWaalsContact OG1-CE1 3.25Å; T483-Y485 WeakPolarHBondContact OG1-CE1 3.45Å; T483-Y485 WeakPolarHBondContact OG1-CE2 3.25Å; Y485-H488 CarbonylContact O-C 3.52Å; Y485-H488 PolarHBondContact O-N 3.42Å; Y485-S489 PolarHBondContact O-N 2.79Å; Y485-L490 PolarHBondContact O-N 3.25Å; Y485-D491 HydrophobicContact CD2-CB 4.26Å
486Q96.4Very high95.2Very high76 Ų7681.3 Ų81.336%0.35540%0.4SS..Hα-helixtrans-67.2-43172.1-75.1171.8-3700111.4L482 T483 H488 S489L482-Q486 HydrophobicContact CB-CB 4.24Å; L482-Q486 HydrophobicContact CD2-CB 4.35Å; T483-Q486 VanDerWaalsContact N-OE1 3.12Å; T483-Q486 PolarHBondContact O-N 2.91Å; T483-Q486 VanDerWaalsContact O-N 3.13Å; T483-Q486 WeakPolarHBondContact OG1-CB 3.28Å; T483-Q486 VanDerWaalsContact OG1-CG 3.29Å; T483-Q486 WeakPolarHBondContact OG1-CG 3.49Å; T483-Q486 PolarHBondContact OG1-N 3.28Å; T483-Q486 PolarHBondContact OG1-OE1 3.12Å; T483-Q486 VanDerWaalsContact OG1-OE1 3.07Å; Q486-H488 PolarHBondContact O-N 2.91Å; Q486-S489 PolarHBondContact O-N 2.76Å
487Y93.6Very high95.5Very high91 Ų9182.5 Ų82.536%0.35741%0.412SS..Hα-helixtrans-56.2-38.8177.2178-96.1000112A479 T483A479-Y487 HydrophobicContact CB-CD2 3.83Å; A479-Y487 HydrophobicContact CB-CE2 3.66Å; T483-Y487 WeakPolarHBondContact O-CB 3.41Å; T483-Y487 PolarHBondContact O-N 3.36Å
488H94Very high95.7Very high115 Ų11585.5 Ų85.553%0.53243%0.425SS..THydrogen-bonded Turntrans-93.16.5176.1-68-59.3000114.2W484 Y485 Q486 L490W484-H488 PolarHBondContact O-CD2 3.38Å; W484-H488 PolarHBondContact O-N 2.89Å; Y485-H488 CarbonylContact O-C 3.52Å; Y485-H488 PolarHBondContact O-N 3.42Å; Q486-H488 PolarHBondContact O-N 2.91Å; H488-L490 HydrophobicContact CB-CD1 4.31Å; H488-L490 HydrophobicContact CB-CD2 4.11Å; H488-L490 HydrophobicContact CB-CG 3.81Å; H488-L490 PolarHBondContact O-N 3.47Å; H488-L490 VanDerWaalsContact O-N 3.15Å
489S97.4Very high95.9Very high60 Ų6082.4 Ų82.442%0.4241%0.412SS..THydrogen-bonded Turntrans52.531.1-177.8-56.40000114.2Y485 Q486 D491 V492 L493Y485-S489 PolarHBondContact O-N 2.79Å; Q486-S489 PolarHBondContact O-N 2.76Å; S489-D491 VanDerWaalsContact C-N 3.3Å; S489-D491 PolarHBondContact O-N 3.46Å; S489-V492 PolarHBondContact O-N 2.81Å; S489-L493 WeakPolarHBondContact O-CG 3.26Å; S489-L493 PolarHBondContact O-N 2.98Å
490L97.6Very high96.1Very high68 Ų6885.8 Ų85.836%0.35643%0.428SS..Hα-helixtrans-69.9-29.6-178-58.6-179.2000112.2W484 Y485 H488 L493 A494W484-L490 HydrophobicContact CE3-CD1 3.99Å; W484-L490 HydrophobicContact CH2-CD1 4.02Å; W484-L490 HydrophobicContact CZ3-CD1 3.29Å; Y485-L490 PolarHBondContact O-N 3.25Å; H488-L490 HydrophobicContact CB-CD1 4.31Å; H488-L490 HydrophobicContact CB-CD2 4.11Å; H488-L490 HydrophobicContact CB-CG 3.81Å; H488-L490 PolarHBondContact O-N 3.47Å; H488-L490 VanDerWaalsContact O-N 3.15Å; L490-L493 HydrophobicContact CD2-CD1 4.27Å; L490-A494 WeakPolarHBondContact O-CB 3.15Å; L490-A494 PolarHBondContact O-N 3.04Å
491D97.6Very high96.4Very high68 Ų6890 Ų9036%0.36445%0.45SS..Hα-helixtrans-62.8-44.3170.853.8-12.7000111.8Y485 S489 A494 F495Y485-D491 HydrophobicContact CD2-CB 4.26Å; S489-D491 VanDerWaalsContact C-N 3.3Å; S489-D491 PolarHBondContact O-N 3.46Å; D491-A494 PolarHBondContact O-N 3.04Å; D491-F495 WeakPolarHBondContact O-CB 3.34Å; D491-F495 PolarHBondContact O-N 3.39Å
492V98.1Very high96.7Very high76 Ų7689 Ų8946%0.46145%0.448SS..Hα-helixtrans-65.4-46.6174.6-179.40000111S489 A494 F495 L496S489-V492 PolarHBondContact O-N 2.81Å; V492-A494 VanDerWaalsContact C-N 3.33Å; V492-A494 PolarHBondContact O-N 3.2Å; V492-F495 WeakPolarHBondContact O-CB 3.38Å; V492-F495 PolarHBondContact O-N 3.23Å; V492-L496 HydrophobicContact CG1-CD1 4.27Å; V492-L496 WeakPolarHBondContact O-CG 3.32Å; V492-L496 PolarHBondContact O-N 3.18Å
493L98.1Very high96.8Very high104 Ų10490.1 Ų90.155%0.54545%0.454SS..Hα-helixtrans-61.8-40.9177.7-69.9175.6000111.9S489 L490 L496 L497S489-L493 WeakPolarHBondContact O-CG 3.26Å; S489-L493 PolarHBondContact O-N 2.98Å; L490-L493 HydrophobicContact CD2-CD1 4.27Å; L493-L496 PolarHBondContact O-N 3.38Å; L493-L497 WeakPolarHBondContact O-CB 3.15Å; L493-L497 PolarHBondContact O-N 2.82Å
494A97.9Very high97Very high48 Ų4893 Ų9340%0.39747%0.466SS..Hα-helixtrans-63.1-42.4174.900000111.6L490 D491 V492 L497 I498L490-A494 WeakPolarHBondContact O-CB 3.15Å; L490-A494 PolarHBondContact O-N 3.04Å; D491-A494 PolarHBondContact O-N 3.04Å; V492-A494 VanDerWaalsContact C-N 3.33Å; V492-A494 PolarHBondContact O-N 3.2Å; A494-L497 PolarHBondContact O-N 2.91Å; A494-I498 WeakPolarHBondContact O-CD1 3.3Å; A494-I498 VanDerWaalsContact O-CG1 3.25Å; A494-I498 WeakPolarHBondContact O-CG1 3.43Å; A494-I498 PolarHBondContact O-N 3.14Å
495F98.3Very high97.2Very high127 Ų12789.8 Ų89.856%0.55746%0.457SS*.Hα-helixtrans-61.1-46.3175.8175.6-104.7000112.4D491 V492 I498 I499D491-F495 WeakPolarHBondContact O-CB 3.34Å; D491-F495 PolarHBondContact O-N 3.39Å; V492-F495 WeakPolarHBondContact O-CB 3.38Å; V492-F495 PolarHBondContact O-N 3.23Å; F495-I498 PolarHBondContact O-N 3.15Å; F495-I499 HydrophobicContact CD1-CD1 3.98Å; F495-I499 HydrophobicContact CE1-CD1 3.41Å; F495-I499 VanDerWaalsContact CE1-CD1 3.41Å; F495-I499 HydrophobicContact CE2-CD1 4.23Å; F495-I499 HydrophobicContact CZ-CD1 3.56Å; F495-I499 HydrophobicContact CZ-CG1 4.41Å; F495-I499 PolarHBondContact O-N 3.15Å; F495-I499 VanDerWaalsContact O-N 3.14Å
496L98.3Very high97.4Very high87 Ų8789.5 Ų89.546%0.45546%0.462SS..Hα-helixtrans-62.5-43.6176.6-67.8175.4000111.8V492 L493 I498 I499 D500V492-L496 HydrophobicContact CG1-CD1 4.27Å; V492-L496 WeakPolarHBondContact O-CG 3.32Å; V492-L496 PolarHBondContact O-N 3.18Å; L493-L496 PolarHBondContact O-N 3.38Å; L496-I498 VanDerWaalsContact C-N 3.3Å; L496-I498 PolarHBondContact O-N 3.49Å; L496-I499 WeakPolarHBondContact O-CB 3.28Å; L496-I499 PolarHBondContact O-N 3.31Å; L496-I499 VanDerWaalsContact O-N 3.13Å; L496-D500 PolarHBondContact O-N 3.4Å
497L98Very high97.4Very high103 Ų10391.3 Ų91.354%0.53947%0.473SS..Hα-helixtrans-60.4-39.7176.6-178.964000112L493 A494 I499 D500 L501L493-L497 WeakPolarHBondContact O-CB 3.15Å; L493-L497 PolarHBondContact O-N 2.82Å; A494-L497 PolarHBondContact O-N 2.91Å; L497-I499 VanDerWaalsContact C-N 3.35Å; L497-D500 PolarHBondContact O-N 2.92Å; L497-L501 HydrophobicContact CD1-CD1 4.37Å; L497-L501 HydrophobicContact CD1-CG 4.31Å; L497-L501 HydrophobicContact CG-CD1 4.08Å; L497-L501 HydrophobicContact CG-CG 4.44Å; L497-L501 WeakPolarHBondContact O-CB 3.18Å; L497-L501 VanDerWaalsContact O-CG 3.23Å; L497-L501 WeakPolarHBondContact O-CG 3.29Å; L497-L501 PolarHBondContact O-N 3.38Å
498I98.3Very high97.5Very high98 Ų9893.4 Ų93.450%0.50348%0.484SS..Hα-helixtrans-62.1-43.5175.7-70.5163.4000110.6A494 F495 L496 L501 L502A494-I498 WeakPolarHBondContact O-CD1 3.3Å; A494-I498 VanDerWaalsContact O-CG1 3.25Å; A494-I498 WeakPolarHBondContact O-CG1 3.43Å; A494-I498 PolarHBondContact O-N 3.14Å; F495-I498 PolarHBondContact O-N 3.15Å; L496-I498 VanDerWaalsContact C-N 3.3Å; L496-I498 PolarHBondContact O-N 3.49Å; I498-L501 PolarHBondContact O-N 3.06Å; I498-L502 HydrophobicContact CG2-CD1 3.96Å; I498-L502 HydrophobicContact CG2-CG 4.42Å; I498-L502 WeakPolarHBondContact O-CB 3.39Å; I498-L502 VanDerWaalsContact O-CG 3.24Å; I498-L502 WeakPolarHBondContact O-CG 3.22Å; I498-L502 PolarHBondContact O-N 2.91Å
499I98.3Very high97.5Very high66 Ų6693.2 Ų93.234%0.33848%0.482SS..Hα-helixtrans-60.6-48.3176.4-69.4170000110.7F495 L496 L497 L501 L502 L503F495-I499 HydrophobicContact CD1-CD1 3.98Å; F495-I499 HydrophobicContact CE1-CD1 3.41Å; F495-I499 VanDerWaalsContact CE1-CD1 3.41Å; F495-I499 HydrophobicContact CE2-CD1 4.23Å; F495-I499 HydrophobicContact CZ-CD1 3.56Å; F495-I499 HydrophobicContact CZ-CG1 4.41Å; F495-I499 PolarHBondContact O-N 3.15Å; F495-I499 VanDerWaalsContact O-N 3.14Å; L496-I499 WeakPolarHBondContact O-CB 3.28Å; L496-I499 PolarHBondContact O-N 3.31Å; L496-I499 VanDerWaalsContact O-N 3.13Å; L497-I499 VanDerWaalsContact C-N 3.35Å; I499-L501 PolarHBondContact O-N 2.89Å; I499-L502 WeakPolarHBondContact O-CB 3.33Å; I499-L502 PolarHBondContact O-N 2.93Å; I499-L503 HydrophobicContact CG2-CD1 4.02Å; I499-L503 HydrophobicContact CG2-CG 4.36Å; I499-L503 WeakPolarHBondContact O-CG 3.23Å; I499-L503 PolarHBondContact O-N 3.43Å
500D97.9Very high97.3Very high88 Ų8893.2 Ų93.247%0.47148%0.482SS..Hα-helixtrans-61-44.3-179.5-72.3-23000111.7L496 L497 L502 L503 I504L496-D500 PolarHBondContact O-N 3.4Å; L497-D500 PolarHBondContact O-N 2.92Å; D500-L502 VanDerWaalsContact C-N 3.34Å; D500-L502 PolarHBondContact O-N 3.24Å; D500-L503 PolarHBondContact O-N 3.4Å; D500-I504 VanDerWaalsContact O-CG1 3.28Å; D500-I504 WeakPolarHBondContact O-CG1 3.41Å; D500-I504 PolarHBondContact O-N 3.09Å
501L98Very high97Very high100 Ų10093.1 Ų93.152%0.52449%0.486SS..Hα-helixtrans-62.9-39.2176-70.3174000112.1L497 I498 I499 F505L497-L501 HydrophobicContact CD1-CD1 4.37Å; L497-L501 HydrophobicContact CD1-CG 4.31Å; L497-L501 HydrophobicContact CG-CD1 4.08Å; L497-L501 HydrophobicContact CG-CG 4.44Å; L497-L501 WeakPolarHBondContact O-CB 3.18Å; L497-L501 VanDerWaalsContact O-CG 3.23Å; L497-L501 WeakPolarHBondContact O-CG 3.29Å; L497-L501 PolarHBondContact O-N 3.38Å; I498-L501 PolarHBondContact O-N 3.06Å; I499-L501 PolarHBondContact O-N 2.89Å; L501-F505 VanDerWaalsContact O-CB 3.28Å; L501-F505 WeakPolarHBondContact O-CB 3.24Å; L501-F505 PolarHBondContact O-N 3.45Å
502L97.9Very high96.5Very high97 Ų9791.8 Ų91.851%0.50848%0.482SS..Hα-helixtrans-65.1-42.8174.9-73.8171.2000111.7I498 I499 D500 F505 I506I498-L502 HydrophobicContact CG2-CD1 3.96Å; I498-L502 HydrophobicContact CG2-CG 4.42Å; I498-L502 WeakPolarHBondContact O-CB 3.39Å; I498-L502 VanDerWaalsContact O-CG 3.24Å; I498-L502 WeakPolarHBondContact O-CG 3.22Å; I498-L502 PolarHBondContact O-N 2.91Å; I499-L502 WeakPolarHBondContact O-CB 3.33Å; I499-L502 PolarHBondContact O-N 2.93Å; D500-L502 VanDerWaalsContact C-N 3.34Å; D500-L502 PolarHBondContact O-N 3.24Å; L502-F505 PolarHBondContact O-N 2.95Å; L502-I506 VanDerWaalsContact O-CG1 3.25Å; L502-I506 WeakPolarHBondContact O-CG1 3.37Å; L502-I506 PolarHBondContact O-N 3.35Å
503L97.4Very high96Very high92 Ų9294.2 Ų94.248%0.48249%0.487SS..Hα-helixtrans-63.6-45.5176.4-70.3174.8000111.5I499 D500 F505 I506 L507I499-L503 HydrophobicContact CG2-CD1 4.02Å; I499-L503 HydrophobicContact CG2-CG 4.36Å; I499-L503 WeakPolarHBondContact O-CG 3.23Å; I499-L503 PolarHBondContact O-N 3.43Å; D500-L503 PolarHBondContact O-N 3.4Å; L503-F505 VanDerWaalsContact C-N 3.3Å; L503-F505 PolarHBondContact O-N 2.84Å; L503-I506 PolarHBondContact O-N 2.86Å; L503-L507 WeakPolarHBondContact O-CB 3.23Å; L503-L507 VanDerWaalsContact O-CG 3.29Å; L503-L507 WeakPolarHBondContact O-CG 3.47Å; L503-L507 PolarHBondContact O-N 3.38Å
504I97.4Very high95.4Very high109 Ų10992.6 Ų92.656%0.55948%0.483SS*.Hα-helixtrans-59.6-43.3174.7-68.7166.3000110.4D500 L507 F508D500-I504 VanDerWaalsContact O-CG1 3.28Å; D500-I504 WeakPolarHBondContact O-CG1 3.41Å; D500-I504 PolarHBondContact O-N 3.09Å; I504-L507 PolarHBondContact O-N 3Å; I504-F508 VanDerWaalsContact O-CB 3.28Å; I504-F508 WeakPolarHBondContact O-CB 3.12Å; I504-F508 PolarHBondContact O-N 3.26Å
505F97.2Very high94.6Very high114 Ų11496 Ų9650%0.549%0.489SS..Hα-helixtrans-63.1-45.1177.5177.6-97.1000112.2L501 L502 L503 F508 K509L501-F505 VanDerWaalsContact O-CB 3.28Å; L501-F505 WeakPolarHBondContact O-CB 3.24Å; L501-F505 PolarHBondContact O-N 3.45Å; L502-F505 PolarHBondContact O-N 2.95Å; L503-F505 VanDerWaalsContact C-N 3.3Å; L503-F505 PolarHBondContact O-N 2.84Å; F505-F508 PolarHBondContact O-N 3.15Å; F505-K509 HydrophobicContact CD1-CG 4.23Å; F505-K509 HydrophobicContact CD2-CG 4.47Å; F505-K509 HydrophobicContact CE1-CG 3.87Å; F505-K509 HydrophobicContact CE2-CD 4.47Å; F505-K509 VanDerWaalsContact CE2-CE 3.45Å; F505-K509 HydrophobicContact CE2-CG 4.15Å; F505-K509 HydrophobicContact CZ-CD 4.23Å; F505-K509 HydrophobicContact CZ-CG 3.85Å; F505-K509 WeakPolarHBondContact O-CB 3.48Å; F505-K509 VanDerWaalsContact O-CG 3.31Å; F505-K509 WeakPolarHBondContact O-CG 3.42Å; F505-K509 PolarHBondContact O-N 3.38Å
506I96.8Very high93.7Very high93 Ų9397.2 Ų97.248%0.47749%0.494SS..Hα-helixtrans-61.4-48.2176.2-69.3166.6000109.9L502 L503 F508 K509 S510L502-I506 VanDerWaalsContact O-CG1 3.25Å; L502-I506 WeakPolarHBondContact O-CG1 3.37Å; L502-I506 PolarHBondContact O-N 3.35Å; L503-I506 PolarHBondContact O-N 2.86Å; I506-F508 PolarHBondContact O-N 3.46Å; I506-K509 PolarHBondContact O-N 2.91Å; I506-S510 VanDerWaalsContact O-CB 3.3Å; I506-S510 WeakPolarHBondContact O-CB 3.3Å; I506-S510 PolarHBondContact O-N 3.44Å; I506-S510 PolarHBondContact O-OG 3.43Å
507L96.3Very high92.7Very high113 Ų113101.6 Ų101.659%0.59251%0.505SS*.Hα-helixtrans-58.2-47.7177.1-73.8170.4000111.2L503 I504 K509 S510 C511L503-L507 WeakPolarHBondContact O-CB 3.23Å; L503-L507 VanDerWaalsContact O-CG 3.29Å; L503-L507 WeakPolarHBondContact O-CG 3.47Å; L503-L507 PolarHBondContact O-N 3.38Å; I504-L507 PolarHBondContact O-N 3Å; L507-K509 PolarHBondContact O-N 3.4Å; L507-S510 PolarHBondContact O-N 3.49Å; L507-C511 WeakPolarHBondContact O-CB 3.48Å; L507-C511 PolarHBondContact O-N 3.08Å; L507-C511 PolarHBondContact O-SG 3.09Å
508F96.1Very high91.6Very high135 Ų135101.5 Ų101.559%0.59251%0.512SS*.Hα-helixtrans-60.3-44.5177.2179.2-97.9000112.2I504 F505 I506 S512I504-F508 VanDerWaalsContact O-CB 3.28Å; I504-F508 WeakPolarHBondContact O-CB 3.12Å; I504-F508 PolarHBondContact O-N 3.26Å; F505-F508 PolarHBondContact O-N 3.15Å; I506-F508 PolarHBondContact O-N 3.46Å; F508-S512 WeakPolarHBondContact O-CB 3.34Å; F508-S512 PolarHBondContact O-N 3.29Å
509K94.9Very high89.8Confident111 Ų111107 Ų10748%0.48353%0.526SS..Hα-helixtrans-66.2-42.2177.4-74-67.6-175.7179.80111.9F505 I506 L507 S512 F513F505-K509 HydrophobicContact CD1-CG 4.23Å; F505-K509 HydrophobicContact CD2-CG 4.47Å; F505-K509 HydrophobicContact CE1-CG 3.87Å; F505-K509 HydrophobicContact CE2-CD 4.47Å; F505-K509 VanDerWaalsContact CE2-CE 3.45Å; F505-K509 HydrophobicContact CE2-CG 4.15Å; F505-K509 HydrophobicContact CZ-CD 4.23Å; F505-K509 HydrophobicContact CZ-CG 3.85Å; F505-K509 WeakPolarHBondContact O-CB 3.48Å; F505-K509 VanDerWaalsContact O-CG 3.31Å; F505-K509 WeakPolarHBondContact O-CG 3.42Å; F505-K509 PolarHBondContact O-N 3.38Å; I506-K509 PolarHBondContact O-N 2.91Å; L507-K509 PolarHBondContact O-N 3.4Å; K509-S512 PolarHBondContact O-N 2.95Å; K509-F513 WeakPolarHBondContact O-CB 3.43Å; K509-F513 PolarHBondContact O-N 3.24Å
510S93Very high87.9Confident60 Ų60106.4 Ų106.442%0.4254%0.536SS..Hα-helixtrans-62.5-48.7175.5-66.90000111.3I506 L507 F513 C514I506-S510 VanDerWaalsContact O-CB 3.3Å; I506-S510 WeakPolarHBondContact O-CB 3.3Å; I506-S510 PolarHBondContact O-N 3.44Å; I506-S510 PolarHBondContact O-OG 3.43Å; L507-S510 PolarHBondContact O-N 3.49Å; S510-F513 PolarHBondContact O-N 2.92Å; S510-C514 WeakPolarHBondContact O-CB 3.38Å; S510-C514 PolarHBondContact O-N 2.96Å; S510-C514 PolarHBondContact O-SG 3.4Å
511C91.6Very high85.9Confident67 Ų67113 Ų11345%0.45356%0.555SS.*Hα-helixtrans-60.5-47.1174.3-70.50000111.6L507 F513 C514 F515L507-C511 WeakPolarHBondContact O-CB 3.48Å; L507-C511 PolarHBondContact O-N 3.08Å; L507-C511 PolarHBondContact O-SG 3.09Å; C511-F513 VanDerWaalsContact C-N 3.31Å; C511-F513 PolarHBondContact O-N 3.15Å; C511-C514 PolarHBondContact O-N 2.94Å; C511-F515 HydrophobicContact CB-CD2 4.47Å; C511-F515 WeakPolarHBondContact O-CB 3.38Å; C511-F515 WeakPolarHBondContact O-CD2 3.43Å; C511-F515 PolarHBondContact O-N 3.24Å
512S87.6Confident83.9Confident39 Ų39117.7 Ų117.727%0.27357%0.571SS.*Hα-helixtrans-60.8-39.7177.1-173.10000112F508 K509 F515 K516F508-S512 WeakPolarHBondContact O-CB 3.34Å; F508-S512 PolarHBondContact O-N 3.29Å; K509-S512 PolarHBondContact O-N 2.95Å; S512-F515 PolarHBondContact O-N 2.74Å; S512-K516 WeakPolarHBondContact O-CB 3.26Å; S512-K516 VanDerWaalsContact O-CG 3.32Å; S512-K516 WeakPolarHBondContact O-CG 3.44Å; S512-K516 PolarHBondContact O-N 3.06Å
513F87.2Confident81.8Confident127 Ų127121.7 Ų121.756%0.55759%0.587SS**Hα-helixtrans-65.1-47174.6-180-98000111.6K509 S510 C511 F515 K516 R517K509-F513 WeakPolarHBondContact O-CB 3.43Å; K509-F513 PolarHBondContact O-N 3.24Å; S510-F513 PolarHBondContact O-N 2.92Å; C511-F513 VanDerWaalsContact C-N 3.31Å; C511-F513 PolarHBondContact O-N 3.15Å; F513-F515 PolarHBondContact O-N 3.4Å; F513-K516 PolarHBondContact O-N 2.8Å; F513-R517 VanDerWaalsContact O-CB 3.31Å; F513-R517 WeakPolarHBondContact O-CB 3.21Å; F513-R517 PolarHBondContact O-N 3.19Å
514C85.1Confident79.6Confident70 Ų70123.1 Ų123.147%0.47360%0.602SS.*Hα-helixtrans-57.9-47173.7-71.40000111.4S510 C511 R517 C518S510-C514 WeakPolarHBondContact O-CB 3.38Å; S510-C514 PolarHBondContact O-N 2.96Å; S510-C514 PolarHBondContact O-SG 3.4Å; C511-C514 PolarHBondContact O-N 2.94Å; C514-R517 PolarHBondContact O-N 2.84Å; C514-R517 VanDerWaalsContact O-N 3.17Å; C514-C518 WeakPolarHBondContact O-CB 3.35Å; C514-C518 PolarHBondContact O-N 3.15Å; C514-C518 PolarHBondContact O-SG 2.9Å
515F81.6Confident77.6Confident119 Ų119128 Ų12852%0.52262%0.619SS.*Hα-helixtrans-61.5-45.4176.4-83-63.7000112.5C511 S512 F513 R517 C518 W519C511-F515 HydrophobicContact CB-CD2 4.47Å; C511-F515 WeakPolarHBondContact O-CB 3.38Å; C511-F515 WeakPolarHBondContact O-CD2 3.43Å; C511-F515 PolarHBondContact O-N 3.24Å; S512-F515 PolarHBondContact O-N 2.74Å; F513-F515 PolarHBondContact O-N 3.4Å; F515-R517 VanDerWaalsContact C-N 3.27Å; F515-R517 PolarHBondContact O-N 3.33Å; F515-C518 PolarHBondContact O-N 3.07Å; F515-W519 AromaticContact CD1-CE3 3.52Å; F515-W519 HydrophobicContact CD1-CE3 3.52Å; F515-W519 HydrophobicContact CD1-CH2 4.13Å; F515-W519 AromaticContact CD1-CZ3 3.25Å; F515-W519 HydrophobicContact CD1-CZ3 3.25Å; F515-W519 HydrophobicContact CE1-CE3 4.12Å; F515-W519 AromaticContact CE1-CH2 3.85Å; F515-W519 HydrophobicContact CE1-CH2 3.85Å; F515-W519 AromaticContact CE1-CZ3 3.38Å; F515-W519 HydrophobicContact CE1-CZ3 3.38Å; F515-W519 HydrophobicContact CG-CZ3 4.42Å; F515-W519 PolarHBondContact O-N 3.26Å
516K79.3Confident75.4Confident153 Ų153134.2 Ų134.267%0.66564%0.639SS**Hα-helixtrans-62.5-33.9174.5-75.5-178.4-176.5-174.30112.3S512 F513 G520S512-K516 WeakPolarHBondContact O-CB 3.26Å; S512-K516 VanDerWaalsContact O-CG 3.32Å; S512-K516 WeakPolarHBondContact O-CG 3.44Å; S512-K516 PolarHBondContact O-N 3.06Å; F513-K516 PolarHBondContact O-N 2.8Å; K516-G520 WeakPolarHBondContact O-CA 3.32Å; K516-G520 PolarHBondContact O-N 3.29Å
517R76.2Confident73.3Confident180 Ų180139.7 Ų139.768%0.67966%0.659SS**Hα-helixtrans-78.1-35.7178.9-169.5172.1176.3122.9-3.8112.8F513 C514 F515F513-R517 VanDerWaalsContact O-CB 3.31Å; F513-R517 WeakPolarHBondContact O-CB 3.21Å; F513-R517 PolarHBondContact O-N 3.19Å; C514-R517 PolarHBondContact O-N 2.84Å; C514-R517 VanDerWaalsContact O-N 3.17Å; F515-R517 VanDerWaalsContact C-N 3.27Å; F515-R517 PolarHBondContact O-N 3.33Å
518C74.7Confident71.3Confident100 Ų100139 Ų13968%0.67667%0.67SS**Hα-helixtrans-79.5-35.8179.2-69.70000113.1C514 F515C514-C518 WeakPolarHBondContact O-CB 3.35Å; C514-C518 PolarHBondContact O-N 3.15Å; C514-C518 PolarHBondContact O-SG 2.9Å; F515-C518 PolarHBondContact O-N 3.07Å
519W62.4Low68.9Low214 Ų214145.2 Ų145.281%0.81170%0.701SS**Hα-helixtrans-107-7.7179.5-79.3-40.5000115.3F515F515-W519 AromaticContact CD1-CE3 3.52Å; F515-W519 HydrophobicContact CD1-CE3 3.52Å; F515-W519 HydrophobicContact CD1-CH2 4.13Å; F515-W519 AromaticContact CD1-CZ3 3.25Å; F515-W519 HydrophobicContact CD1-CZ3 3.25Å; F515-W519 HydrophobicContact CE1-CE3 4.12Å; F515-W519 AromaticContact CE1-CH2 3.85Å; F515-W519 HydrophobicContact CE1-CH2 3.85Å; F515-W519 AromaticContact CE1-CZ3 3.38Å; F515-W519 HydrophobicContact CE1-CZ3 3.38Å; F515-W519 HydrophobicContact CG-CZ3 4.42Å; F515-W519 PolarHBondContact O-N 3.26Å
520G58.3Low67.6Low53 Ų53147 Ų14755%0.54671%0.712SS.*  trans-90.54.1-179.400000116.3K516 K522K516-G520 WeakPolarHBondContact O-CA 3.32Å; K516-G520 PolarHBondContact O-N 3.29Å; G520-K522 VanDerWaalsContact C-N 3.3Å; G520-K522 PolarHBondContact O-N 3.37Å
521R54.4Low66.2Low228 Ų228151.5 Ų151.586%0.8673%0.727SS**  trans-72.285.9169.1-81.2-173.1174.9179.4-1.2109.6Q523R521-Q523 PolarHBondContact O-N 3.38Å
522K56.8Low64.8Low198 Ų198156.2 Ų156.286%0.86174%0.742SS**PPolyproline II helixtrans-57.8125.9159.8-77.7-176.2176179.20107.9G520G520-K522 VanDerWaalsContact C-N 3.3Å; G520-K522 PolarHBondContact O-N 3.37Å
523Q53.5Low63.5Low181 Ų181163.1 Ų163.185%0.84677%0.77SS**PPolyproline II helixtrans-54.4136.5171.6-76.1-159-7.600109.9R521 K525R521-Q523 PolarHBondContact O-N 3.38Å; Q523-K525 PolarHBondContact O-N 3.34Å
524P52.3Low62Low122 Ų122165.4 Ų165.479%0.79278%0.783SS**PPolyproline II helixtrans-64.6123.7171.326.6-30.2000108.3R526P524-R526 PolarHBondContact O-N 3.11Å
525K53.9Low60.5Low210 Ų210171.7 Ų171.791%0.91380%0.804SS**  trans-56.3115.1170.4-82.4-175.4172.7-176.10108.2Q523 K527Q523-K525 PolarHBondContact O-N 3.34Å; K525-K527 PolarHBondContact O-N 3.12Å
526R52.1Low59Low245 Ų245175.5 Ų175.593%0.92582%0.824SS**PPolyproline II helixtrans-55.1123.2164.3-108.6177.2168176-4.7107.6P524 A528P524-R526 PolarHBondContact O-N 3.11Å; R526-A528 PolarHBondContact O-N 3.33Å
527K52.2Low57.4Low208 Ų208177.2 Ų177.290%0.90484%0.836SS**PPolyproline II helixtrans-63.5123.2163.1-82.9-178.2172.1-176.60107K525K525-K527 PolarHBondContact O-N 3.12Å
528A54.2Low55.8Low98 Ų98177 Ų17781%0.8185%0.849SS**PPolyproline II helixtrans-81.2130.2165.300000107.6R526R526-A528 PolarHBondContact O-N 3.33Å
529E45.1Very low54.1Low267 Ų267184 Ų184100%1.24887%0.865SS**  trans-70.40163.4-76.7177.5156.800111

Retrieved 529 of 529 residues in 1468.8 ms (Link to these results)