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Non-lysosomal glucosylceramidase

Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

AlphaFold DB , UniProt , Accession A0A087XKD5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 863 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39.5Very low51.3Low138 Ų13892.5 Ų92.568%0.6850%0.498SS*.  0111.70-69.3-177.9-157.100110S3 P418 M791M1-S3 PolarHBondContact O-N 3.13Å; M1-P418 HydrophobicContact SD-CB 4.5Å; M1-P418 HydrophobicContact SD-CG 4.43Å; M1-M791 HydrophobicContact CE-CG 4.21Å
2T31.1Very low54.1Low112 Ų11293.7 Ų93.769%0.68750%0.504SS*.  trans-71.1116.7173.345.10000109.6E4T2-E4 PolarHBondContact O-N 3.18Å
3S39.2Very low56.6Low88 Ų8887.2 Ų87.262%0.61547%0.469SS*.THydrogen-bonded Turntrans-57.8-12.4-179.652.50000115M1 W5 G6M1-S3 PolarHBondContact O-N 3.13Å; S3-W5 VanDerWaalsContact C-N 3.29Å; S3-W5 PolarHBondContact O-N 3.42Å; S3-G6 PolarHBondContact O-N 2.97Å
4E42.2Very low59.1Low125 Ų12582.9 Ų82.958%0.58445%0.445SS*.Hα-helixtrans-64.6-23.3-173.7-72-164.5155.500115.4T2 K8T2-E4 PolarHBondContact O-N 3.18Å; E4-K8 WeakPolarHBondContact O-CD 3.41Å; E4-K8 WeakPolarHBondContact O-CE 3.34Å; E4-K8 WeakPolarHBondContact O-CG 3.35Å
5W44.1Very low61.1Low125 Ų12583.4 Ų83.447%0.47346%0.458SS..Hα-helixtrans-89.7-30.4-179.3-78.378.1000113.3S3 H746 R799S3-W5 VanDerWaalsContact C-N 3.29Å; S3-W5 PolarHBondContact O-N 3.42Å; W5-H746 AromaticContact CH2-CE1 3.24Å; W5-H746 WeakPolarHBondContact CH2-CE1 3.46Å; W5-H746 AromaticContact CH2-NE2 3.8Å; W5-H746 AromaticContact CZ3-CE1 3.38Å; W5-H746 WeakPolarHBondContact CZ3-CE1 3.11Å; W5-R799 PolarHBondContact O-NH2 3.48Å
6G44.1Very low63.1Low26 Ų2684.6 Ų84.627%0.26845%0.453SS..Hα-helixtrans-67.7-52.3-177.900000113.4S3S3-G6 PolarHBondContact O-N 2.97Å
7E51.2Low64.8Low155 Ų15581.1 Ų81.172%0.72443%0.433SS*.Hα-helixtrans-71.5-31.7-176-70-177161.600112.9S9 A11E7-S9 PolarHBondContact O-N 3.22Å; E7-A11 VanDerWaalsContact O-CB 3.24Å; E7-A11 WeakPolarHBondContact O-CB 3.45Å; E7-A11 PolarHBondContact O-N 2.86Å
8K58.2Low66.3Low120 Ų12079.8 Ų79.852%0.52244%0.436SS..Hα-helixtrans-61.7-41.3-178.7-77-179.6-171.6167.60112.8E4 A11 D12E4-K8 WeakPolarHBondContact O-CD 3.41Å; E4-K8 WeakPolarHBondContact O-CE 3.34Å; E4-K8 WeakPolarHBondContact O-CG 3.35Å; K8-A11 WeakPolarHBondContact O-CB 3.45Å; K8-A11 PolarHBondContact O-N 2.99Å; K8-D12 WeakPolarHBondContact O-CB 3.47Å; K8-D12 PolarHBondContact O-N 3.12Å
9S66.6Low67.4Low22 Ų2276.3 Ų76.315%0.15442%0.417CS..Hα-helixtrans-74-43.5-173.2-170.40000114.4E7 A11 D12 L13 E803E7-S9 PolarHBondContact O-N 3.22Å; S9-A11 VanDerWaalsContact C-N 3.28Å; S9-A11 PolarHBondContact O-N 2.95Å; S9-D12 WeakPolarHBondContact O-CB 3.28Å; S9-D12 PolarHBondContact O-N 2.81Å; S9-D12 VanDerWaalsContact O-N 3.13Å; S9-L13 PolarHBondContact O-N 3.45Å; S9-E803 VanDerWaalsContact CB-OE2 3.32Å; S9-E803 WeakPolarHBondContact CB-OE2 3.38Å; S9-E803 PolarHBondContact OG-OE1 2.98Å; S9-E803 PolarHBondContact OG-OE2 3.18Å
10T71.3Confident68.2Low48 Ų4882.7 Ų82.729%0.29444%0.441SS..Hα-helixtrans-64.9-37.6173.7-53.30000110.7D12 L13 M14 R32T10-D12 VanDerWaalsContact C-N 3.28Å; T10-D12 PolarHBondContact O-N 3.01Å; T10-L13 PolarHBondContact O-N 3.31Å; T10-M14 HydrophobicContact CG2-CG 4.38Å; T10-M14 VanDerWaalsContact O-CB 3.26Å; T10-M14 WeakPolarHBondContact O-CB 3.33Å; T10-M14 WeakPolarHBondContact O-CG 3.47Å; T10-M14 PolarHBondContact O-N 3.25Å; T10-R32 HydrophobicContact CG2-CB 4.34Å
11A77.5Confident69Low58 Ų5880.9 Ų80.948%0.47943%0.43SS..Hα-helixtrans-60-39172.200000111.7E7 K8 S9 M14 S15E7-A11 VanDerWaalsContact O-CB 3.24Å; E7-A11 WeakPolarHBondContact O-CB 3.45Å; E7-A11 PolarHBondContact O-N 2.86Å; K8-A11 WeakPolarHBondContact O-CB 3.45Å; K8-A11 PolarHBondContact O-N 2.99Å; S9-A11 VanDerWaalsContact C-N 3.28Å; S9-A11 PolarHBondContact O-N 2.95Å; A11-M14 CarbonylContact O-C 3.58Å; A11-M14 PolarHBondContact O-N 2.93Å; A11-S15 WeakPolarHBondContact O-CA 2.87Å; A11-S15 WeakPolarHBondContact O-CB 3.41Å; A11-S15 PolarHBondContact O-N 3.06Å
12D83.8Confident71.4Confident107 Ų10778.3 Ų78.357%0.57242%0.417SS*.Hα-helixtrans-66.9-46.3176.4-71.1-22.1000112.4K8 S9 T10 M14 S15K8-D12 WeakPolarHBondContact O-CB 3.47Å; K8-D12 PolarHBondContact O-N 3.12Å; S9-D12 WeakPolarHBondContact O-CB 3.28Å; S9-D12 PolarHBondContact O-N 2.81Å; S9-D12 VanDerWaalsContact O-N 3.13Å; T10-D12 VanDerWaalsContact C-N 3.28Å; T10-D12 PolarHBondContact O-N 3.01Å; D12-M14 PolarHBondContact O-N 3.15Å; D12-S15 WeakPolarHBondContact O-CB 3.27Å; D12-S15 PolarHBondContact O-N 3.17Å; D12-S15 PolarHBondContact O-OG 3.35Å
13L87.1Confident74.4Confident9 Ų973.9 Ų73.95%0.04739%0.393CS..Hα-helixtrans-62.3-30.3175.5-72.9177.4000112.7S9 T10 E803S9-L13 PolarHBondContact O-N 3.45Å; T10-L13 PolarHBondContact O-N 3.31Å; L13-E803 HydrophobicContact CD1-CB 4.2Å; L13-E803 HydrophobicContact CD1-CG 4.08Å
14M91.5Very high77.1Confident27 Ų2773.9 Ų73.913%0.13338%0.384CS..THydrogen-bonded Turntrans-97.21.6179.3-68.5-63.3-68.700113.9T10 A11 D12 R16 Y17 R32 C34 F172T10-M14 HydrophobicContact CG2-CG 4.38Å; T10-M14 VanDerWaalsContact O-CB 3.26Å; T10-M14 WeakPolarHBondContact O-CB 3.33Å; T10-M14 WeakPolarHBondContact O-CG 3.47Å; T10-M14 PolarHBondContact O-N 3.25Å; A11-M14 CarbonylContact O-C 3.58Å; A11-M14 PolarHBondContact O-N 2.93Å; D12-M14 PolarHBondContact O-N 3.15Å; M14-R16 PolarHBondContact O-N 2.94Å; M14-R16 VanDerWaalsContact O-N 3.08Å; M14-Y17 HydrophobicContact CE-CD1 3.39Å; M14-Y17 HydrophobicContact CE-CD2 4.44Å; M14-Y17 HydrophobicContact CE-CE1 4.14Å; M14-Y17 HydrophobicContact CE-CG 3.56Å; M14-Y17 VanDerWaalsContact O-CB 3.31Å; M14-Y17 WeakPolarHBondContact O-CB 3.48Å; M14-Y17 PolarHBondContact O-N 2.99Å; M14-R32 HydrophobicContact CE-CG 4.2Å; M14-R32 HydrophobicContact CG-CB 4.49Å; M14-R32 HydrophobicContact CG-CG 4.16Å; M14-R32 HydrophobicContact SD-CB 4.4Å; M14-R32 HydrophobicContact SD-CG 3.6Å; M14-R32 VanDerWaalsContact SD-CG 3.6Å; M14-C34 HydrophobicContact SD-CB 4.42Å; M14-F172 HydrophobicContact CE-CB 3.67Å; M14-F172 HydrophobicContact CE-CD1 3.83Å; M14-F172 HydrophobicContact CE-CD2 4.42Å; M14-F172 HydrophobicContact CE-CG 3.72Å; M14-F172 HydrophobicContact SD-CB 3.88Å; M14-F172 HydrophobicContact SD-CG 4.36Å
15S89.9Confident79.5Confident91 Ų9170.4 Ų70.464%0.63638%0.382SS*.THydrogen-bonded Turntrans-59.9-25.4-174.959.30000114.2A11 D12A11-S15 WeakPolarHBondContact O-CA 2.87Å; A11-S15 WeakPolarHBondContact O-CB 3.41Å; A11-S15 PolarHBondContact O-N 3.06Å; D12-S15 WeakPolarHBondContact O-CB 3.27Å; D12-S15 PolarHBondContact O-N 3.17Å; D12-S15 PolarHBondContact O-OG 3.35Å
16R92Very high82.1Confident102 Ų10265.5 Ų65.539%0.38537%0.365SS..THydrogen-bonded Turntrans-89.3-8175.9-67.3-171.366.4172.55.2114.2M14 A18 C34 A36 E169M14-R16 PolarHBondContact O-N 2.94Å; M14-R16 VanDerWaalsContact O-N 3.08Å; R16-A18 PolarHBondContact O-N 2.9Å; R16-C34 HydrophobicContact CB-CB 4.48Å; R16-A36 PolarHBondContact NH1-O 2.64Å; R16-E169 IonicContact CZ-OE1 2.76Å; R16-E169 IonicContact NE-OE1 3.37Å; R16-E169 IonicContact NH2-OE1 3.03Å; R16-E169 PolarHBondContact NH2-OE1 3.05Å; R16-E169 WeakPolarHBondContact O-CB 3.31Å
17Y93.1Very high84.5Confident25 Ų2565.6 Ų65.610%0.09836%0.361CS..  trans-75.4118179.5-175.9-123.7000109.6M14 S19 E21 E169 F172M14-Y17 HydrophobicContact CE-CD1 3.39Å; M14-Y17 HydrophobicContact CE-CD2 4.44Å; M14-Y17 HydrophobicContact CE-CE1 4.14Å; M14-Y17 HydrophobicContact CE-CG 3.56Å; M14-Y17 VanDerWaalsContact O-CB 3.31Å; M14-Y17 WeakPolarHBondContact O-CB 3.48Å; M14-Y17 PolarHBondContact O-N 2.99Å; Y17-S19 WeakPolarHBondContact CD1-O 3.37Å; Y17-S19 WeakPolarHBondContact CE1-O 3.5Å; Y17-S19 VanDerWaalsContact OH-CB 3.3Å; Y17-S19 WeakPolarHBondContact OH-CB 3.45Å; Y17-E21 WeakPolarHBondContact CE1-O 3.3Å; Y17-E21 PolarHBondContact OH-O 2.82Å; Y17-E169 CarbonylContact C-O 3.58Å; Y17-E169 WeakPolarHBondContact CA-O 3.45Å; Y17-E169 VanDerWaalsContact CD2-O 3.28Å; Y17-E169 WeakPolarHBondContact CD2-O 3.41Å; Y17-F172 HydrophobicContact CD1-CD1 4.1Å; Y17-F172 HydrophobicContact CD2-CB 4.39Å; Y17-F172 HydrophobicContact CD2-CD1 4.18Å; Y17-F172 AromaticContact CE1-CD1 3.56Å; Y17-F172 HydrophobicContact CE1-CD1 3.56Å; Y17-F172 AromaticContact CE1-CE1 3.8Å; Y17-F172 HydrophobicContact CE1-CE1 3.8Å; Y17-F172 AromaticContact CE2-CD1 3.69Å; Y17-F172 HydrophobicContact CE2-CD1 3.69Å; Y17-F172 HydrophobicContact CE2-CE1 4.48Å; Y17-F172 HydrophobicContact CG-CD1 4.37Å; Y17-F172 AromaticContact CZ-CD1 3.33Å; Y17-F172 AromaticContact CZ-CE1 3.71Å
18A91.6Very high86.4Confident59 Ų5966.6 Ų66.649%0.48836%0.363SS..  trans-79.4-25.6-172.500000113.1R16 E169 Y170R16-A18 PolarHBondContact O-N 2.9Å; A18-E169 PolarHBondContact N-O 3.1Å; A18-Y170 HydrophobicContact CB-CD1 4.09Å; A18-Y170 HydrophobicContact CB-CE1 3.86Å
19S86.8Confident88.1Confident13 Ų1362 Ų629%0.09134%0.344CS..  trans-86.9157.4-179.8-1630000112.1Y17 E21 Q185Y17-S19 WeakPolarHBondContact CD1-O 3.37Å; Y17-S19 WeakPolarHBondContact CE1-O 3.5Å; Y17-S19 VanDerWaalsContact OH-CB 3.3Å; Y17-S19 WeakPolarHBondContact OH-CB 3.45Å; S19-E21 WeakPolarHBondContact OG-CB 3.38Å; S19-E21 WeakPolarHBondContact OG-CG 3.24Å; S19-E21 PolarHBondContact OG-N 2.76Å; S19-E21 VanDerWaalsContact OG-N 3.14Å; S19-Q185 PolarHBondContact OG-OE1 3.46Å
20K83.1Confident89.5Confident204 Ų20461.6 Ų61.689%0.88734%0.343SS*.  trans-98.8-0.6166.7-63.8-176.3179.8-179.40112.6
21E85.7Confident90.7Very high45 Ų4559.5 Ų59.521%0.2133%0.329CS..  trans-75.2138.3-177.9-63.4177.6164.600110.8Y17 S19 F172 T192 K223Y17-E21 WeakPolarHBondContact CE1-O 3.3Å; Y17-E21 PolarHBondContact OH-O 2.82Å; S19-E21 WeakPolarHBondContact OG-CB 3.38Å; S19-E21 WeakPolarHBondContact OG-CG 3.24Å; S19-E21 PolarHBondContact OG-N 2.76Å; S19-E21 VanDerWaalsContact OG-N 3.14Å; E21-F172 WeakPolarHBondContact O-CE1 3.5Å; E21-T192 WeakPolarHBondContact OE2-CG2 3.49Å; E21-T192 PolarHBondContact OE2-OG1 2.88Å; E21-K223 IonicContact OE1-NZ 3.14Å; E21-K223 PolarHBondContact OE1-NZ 2.93Å; E21-K223 IonicContact OE2-NZ 3.84Å; E21-K223 PolarHBondContact OE2-NZ 3.11Å
22M90.5Very high91.6Very high84 Ų8458.1 Ų58.141%0.41431%0.312SS..  trans-97.6-8.4179.3-67.9-63.7-60.200112.7V26 R32 F172M22-V26 VanDerWaalsContact O-CB 3.3Å; M22-V26 WeakPolarHBondContact O-CB 3.32Å; M22-V26 WeakPolarHBondContact O-CG2 3.35Å; M22-R32 VanDerWaalsContact CE-NH1 3.27Å; M22-F172 WeakPolarHBondContact O-CZ 3.34Å
23G93.5Very high92.2Very high18 Ų1853 Ų5319%0.18629%0.285CS..  trans70.6164.1-169.900000113.1T194G23-T194 VanDerWaalsContact CA-OG1 3.27Å; G23-T194 WeakPolarHBondContact CA-OG1 3.45Å
24Q94.9Very high92.7Very high89 Ų8952.6 Ų52.642%0.41628%0.282SS..THydrogen-bonded Turntrans-73128.9-179.1-178.261.419.100111.3V26 T194 D219 E221 L348Q24-V26 PolarHBondContact O-N 2.57Å; Q24-V26 VanDerWaalsContact O-N 3.15Å; Q24-T194 PolarHBondContact N-OG1 3.37Å; Q24-T194 VanDerWaalsContact N-OG1 3.16Å; Q24-T194 WeakPolarHBondContact O-CG2 3.2Å; Q24-D219 HydrophobicContact CB-CB 3.93Å; Q24-D219 HydrophobicContact CG-CB 4.14Å; Q24-E221 PolarHBondContact N-OE1 2.83Å; Q24-L348 HydrophobicContact CB-CD1 4.48Å; Q24-L348 HydrophobicContact CG-CD1 4.39Å; Q24-L348 HydrophobicContact CG-CD2 4.17Å
25G93.9Very high93Very high52 Ų5251.4 Ų51.454%0.53628%0.276SS..THydrogen-bonded Turntrans6714.3170.900000115.8W181G25-W181 PolarHBondContact O-NE1 2.8Å
26V96.9Very high93.3Very high22 Ų2247.7 Ų47.713%0.13325%0.251CS..  trans-75.8125.7175.8-177.70000109.5M22 Q24 F172 H174 W181 V183 T194M22-V26 VanDerWaalsContact O-CB 3.3Å; M22-V26 WeakPolarHBondContact O-CB 3.32Å; M22-V26 WeakPolarHBondContact O-CG2 3.35Å; Q24-V26 PolarHBondContact O-N 2.57Å; Q24-V26 VanDerWaalsContact O-N 3.15Å; V26-F172 HydrophobicContact CG1-CE2 4.27Å; V26-H174 HydrophobicContact CG1-CB 4Å; V26-W181 HydrophobicContact CG1-CG 4.46Å; V26-W181 HydrophobicContact CG2-CB 3.98Å; V26-W181 HydrophobicContact CG2-CG 3.91Å; V26-V183 HydrophobicContact CG2-CG2 3.82Å; V26-T194 HydrophobicContact CG2-CG2 4.01Å
27P94.9Very high93.5Very high28 Ų2844.3 Ų44.318%0.18224%0.24CC..  trans-67.6157.2179.224.8-30000111.9R32 H174 L176 W181P27-R32 PolarHBondContact O-NH2 2.78Å; P27-R32 VanDerWaalsContact O-NH2 3.13Å; P27-H174 PolarHBondContact O-NE2 2.76Å; P27-L176 HydrophobicContact CB-CD2 4.32Å; P27-L176 HydrophobicContact CG-CB 4.48Å; P27-L176 HydrophobicContact CG-CD2 4.07Å; P27-W181 VanDerWaalsContact CD-CZ2 3.46Å; P27-W181 HydrophobicContact CG-CE3 4.23Å; P27-W181 HydrophobicContact CG-CH2 3.51Å; P27-W181 HydrophobicContact CG-CZ2 3.99Å; P27-W181 HydrophobicContact CG-CZ3 3.64Å
28K92.3Very high93.5Very high175 Ų17549.6 Ų49.676%0.76127%0.265SS*.SBendtrans-67.3-47.5176.7-176.4-175.2174.7-169.30111.1R32K28-R32 PolarHBondContact O-NH2 3.11Å
29E94.1Very high93.5Very high25 Ų2547.3 Ų47.312%0.11724%0.244CC..SBendtrans-88.6146.6-175.4-52-58.5157.800111.4H174 L412 P419 K422E29-H174 PolarHBondContact O-CE1 3.16Å; E29-H174 PolarHBondContact O-NE2 2.94Å; E29-L412 HydrophobicContact CB-CD2 3.85Å; E29-L412 HydrophobicContact CG-CD2 4.15Å; E29-P419 WeakPolarHBondContact OE2-CA 3.35Å; E29-P419 WeakPolarHBondContact OE2-CB 3.27Å; E29-K422 HydrophobicContact CB-CD 4.47Å; E29-K422 HydrophobicContact CG-CD 3.93Å
30G94.9Very high93.5Very high13 Ų1356.3 Ų56.313%0.13428%0.282CS..SBendtrans134.5178.5179.900000112A175G30-A175 WeakPolarHBondContact CA-O 3.22Å
31W96.8Very high93.7Very high3 Ų348.4 Ų48.41%0.01125%0.248CC..EExtended strand (participates in β ladder)trans-84.8119.3178.2179.962.7000109.7I33 F39 W111 Y173 H174 A175 S423 W802 A808 F809W31-I33 HydrophobicContact CH2-CD1 4.25Å; W31-I33 HydrophobicContact CH2-CG2 3.94Å; W31-I33 HydrophobicContact CZ2-CB 4.28Å; W31-I33 HydrophobicContact CZ2-CD1 3.84Å; W31-I33 HydrophobicContact CZ2-CG2 4.1Å; W31-I33 HydrophobicContact CZ3-CG2 4.17Å; W31-F39 HydrophobicContact CZ2-CZ 4.2Å; W31-W111 HydrophobicContact CH2-CB 4.4Å; W31-W111 HydrophobicContact CH2-CG 4.23Å; W31-W111 HydrophobicContact CZ3-CB 4.23Å; W31-Y173 HydrophobicContact CE3-CD1 4.14Å; W31-Y173 HydrophobicContact CE3-CE1 4.03Å; W31-Y173 AromaticContact CZ3-CD1 3.93Å; W31-Y173 HydrophobicContact CZ3-CD1 3.93Å; W31-Y173 AromaticContact CZ3-CE1 3.87Å; W31-Y173 HydrophobicContact CZ3-CE1 3.87Å; W31-H174 CarbonylContact O-C 3.6Å; W31-H174 VanDerWaalsContact O-CA 3.24Å; W31-H174 WeakPolarHBondContact O-CA 3.45Å; W31-A175 HydrophobicContact CE3-CB 4.45Å; W31-A175 PolarHBondContact N-O 3.47Å; W31-A175 PolarHBondContact O-N 2.82Å; W31-S423 PolarHBondContact N-OG 3.43Å; W31-W802 HydrophobicContact CB-CE3 4.26Å; W31-W802 HydrophobicContact CB-CZ3 4.43Å; W31-W802 HydrophobicContact CD2-CE3 4.07Å; W31-W802 HydrophobicContact CD2-CZ3 4.33Å; W31-W802 HydrophobicContact CE3-CZ3 4.38Å; W31-W802 AromaticContact CG-CE3 3.93Å; W31-W802 HydrophobicContact CG-CE3 3.93Å; W31-W802 HydrophobicContact CG-CZ3 4.37Å; W31-W802 PolarHBondContact NE1-O 2.71Å; W31-A808 HydrophobicContact CD2-CB 4.21Å; W31-A808 HydrophobicContact CE3-CB 4.06Å; W31-A808 HydrophobicContact CH2-CB 3.48Å; W31-A808 VanDerWaalsContact CH2-CB 3.48Å; W31-A808 HydrophobicContact CZ2-CB 3.63Å; W31-A808 HydrophobicContact CZ3-CB 3.71Å; W31-F809 AromaticContact CE3-CE2 3.86Å; W31-F809 HydrophobicContact CE3-CE2 3.86Å; W31-F809 HydrophobicContact CZ3-CD2 4.33Å; W31-F809 AromaticContact CZ3-CE2 3.91Å; W31-F809 HydrophobicContact CZ3-CE2 3.91Å
32R96.1Very high93.7Very high30 Ų3052.5 Ų52.511%0.11327%0.265CS..EExtended strand (participates in β ladder)trans-119.6134.6-179.2-160.1179.8-70.9133.59.3111.4T10 M14 M22 P27 K28 F172 Y173 H174T10-R32 HydrophobicContact CG2-CB 4.34Å; M14-R32 HydrophobicContact CE-CG 4.2Å; M14-R32 HydrophobicContact CG-CB 4.49Å; M14-R32 HydrophobicContact CG-CG 4.16Å; M14-R32 HydrophobicContact SD-CB 4.4Å; M14-R32 HydrophobicContact SD-CG 3.6Å; M14-R32 VanDerWaalsContact SD-CG 3.6Å; M22-R32 VanDerWaalsContact CE-NH1 3.27Å; P27-R32 PolarHBondContact O-NH2 2.78Å; P27-R32 VanDerWaalsContact O-NH2 3.13Å; K28-R32 PolarHBondContact O-NH2 3.11Å; R32-F172 HydrophobicContact CG-CD2 3.6Å; R32-F172 HydrophobicContact CG-CE2 4.07Å; R32-F172 HydrophobicContact CG-CG 4.31Å; R32-Y173 WeakPolarHBondContact CA-O 3.41Å; R32-Y173 WeakPolarHBondContact CG-O 3.23Å; R32-H174 HydrophobicContact CG-CB 4.34Å; R32-H174 PolarHBondContact NE-ND1 2.72Å
33I96.7Very high93.6Very high0 Ų049.2 Ų49.20%025%0.248CC..EExtended strand (participates in β ladder)trans-146.3132.9-177.5-172.3167.2000111.7W31 H37 F39 W111 F172 Y173W31-I33 HydrophobicContact CH2-CD1 4.25Å; W31-I33 HydrophobicContact CH2-CG2 3.94Å; W31-I33 HydrophobicContact CZ2-CB 4.28Å; W31-I33 HydrophobicContact CZ2-CD1 3.84Å; W31-I33 HydrophobicContact CZ2-CG2 4.1Å; W31-I33 HydrophobicContact CZ3-CG2 4.17Å; I33-H37 HydrophobicContact CD1-CB 3.93Å; I33-H37 HydrophobicContact CG1-CB 3.63Å; I33-F39 HydrophobicContact CD1-CE1 4.42Å; I33-F39 HydrophobicContact CD1-CE2 3.81Å; I33-F39 HydrophobicContact CD1-CZ 3.48Å; I33-F39 VanDerWaalsContact CD1-CZ 3.48Å; I33-W111 HydrophobicContact CD1-CD2 4.35Å; I33-W111 HydrophobicContact CD1-CE3 4.27Å; I33-W111 HydrophobicContact CD1-CH2 4.18Å; I33-W111 HydrophobicContact CD1-CZ2 4.32Å; I33-W111 HydrophobicContact CD1-CZ3 4.17Å; I33-W111 HydrophobicContact CG1-CE3 4.34Å; I33-W111 HydrophobicContact CG1-CZ3 4.21Å; I33-W111 HydrophobicContact CG2-CB 4.25Å; I33-W111 HydrophobicContact CG2-CD2 4.18Å; I33-W111 HydrophobicContact CG2-CE3 3.89Å; I33-W111 HydrophobicContact CG2-CG 4.35Å; I33-F172 CarbonylContact O-C 3.6Å; I33-F172 VanDerWaalsContact O-CA 3.3Å; I33-F172 WeakPolarHBondContact O-CA 3.43Å; I33-F172 WeakPolarHBondContact O-CB 3.47Å; I33-Y173 HydrophobicContact CG2-CD1 4.12Å; I33-Y173 PolarHBondContact N-O 3.39Å; I33-Y173 PolarHBondContact O-N 2.88Å
34C97.4Very high93.4Very high0 Ų055.2 Ų55.20%027%0.269CS..EExtended strand (participates in β ladder)trans-66.5137.3172.8174.80000110.6M14 R16 A36 H37 W111 G168M14-C34 HydrophobicContact SD-CB 4.42Å; R16-C34 HydrophobicContact CB-CB 4.48Å; C34-A36 PolarHBondContact O-N 2.85Å; C34-A36 VanDerWaalsContact O-N 3.12Å; C34-H37 WeakPolarHBondContact O-CB 3.32Å; C34-H37 PolarHBondContact O-N 3.22Å; C34-W111 VanDerWaalsContact O-CZ3 3.32Å; C34-W111 WeakPolarHBondContact O-CZ3 3.42Å; C34-G168 PolarHBondContact SG-O 3.45Å; C34-G168 VanDerWaalsContact SG-O 3.35Å
35L97.4Very high93Very high1 Ų152 Ų521%0.00526%0.256CS..THydrogen-bonded Turntrans-62.7-22.5-178.1-97.269.4000112.9W111 R112 V153 G168 A171 F172 T182 Y184L35-W111 WeakPolarHBondContact CD1-O 3.48Å; L35-R112 HydrophobicContact CG-CG 4.33Å; L35-R112 VanDerWaalsContact O-CZ 3.25Å; L35-R112 PolarHBondContact O-NE 2.52Å; L35-R112 VanDerWaalsContact O-NE 3.16Å; L35-R112 PolarHBondContact O-NH2 3.38Å; L35-V153 HydrophobicContact CB-CG1 4.22Å; L35-V153 HydrophobicContact CD2-CG1 4.29Å; L35-G168 WeakPolarHBondContact CB-O 3.43Å; L35-G168 PolarHBondContact N-O 2.98Å; L35-A171 HydrophobicContact CB-CB 4.09Å; L35-A171 HydrophobicContact CD1-CB 4.09Å; L35-A171 HydrophobicContact CD2-CB 3.79Å; L35-A171 HydrophobicContact CG-CB 4.19Å; L35-A171 PolarHBondContact N-O 3.35Å; L35-F172 VanDerWaalsContact CD1-CA 3.45Å; L35-T182 HydrophobicContact CD1-CG2 4.19Å; L35-T182 HydrophobicContact CD2-CG2 4.32Å; L35-Y184 HydrophobicContact CD2-CE1 4.09Å
36A96.3Very high92.5Very high13 Ų1352 Ų5211%0.10724%0.241CC..THydrogen-bonded Turntrans-84.8-1.7173.300000114.3R16 C34 G168 E169R16-A36 PolarHBondContact NH1-O 2.64Å; C34-A36 PolarHBondContact O-N 2.85Å; C34-A36 VanDerWaalsContact O-N 3.12Å; A36-G168 PolarHBondContact N-O 2.97Å; A36-E169 HydrophobicContact CB-CG 3.63Å
37H95.9Very high91.6Very high32 Ų3254.9 Ų54.915%0.14825%0.253CS..  trans-60.7145.4-178.1-173.983.9000112I33 C34 F39 W111 R112I33-H37 HydrophobicContact CD1-CB 3.93Å; I33-H37 HydrophobicContact CG1-CB 3.63Å; C34-H37 WeakPolarHBondContact O-CB 3.32Å; C34-H37 PolarHBondContact O-N 3.22Å; H37-F39 AromaticContact NE2-CD1 3.69Å; H37-F39 AromaticContact NE2-CE1 3.83Å; H37-W111 HydrophobicContact CB-CH2 4.31Å; H37-W111 WeakPolarHBondContact O-CH2 3.49Å; H37-R112 PolarHBondContact O-NH2 2.92Å
38E93.3Very high90.3Very high136 Ų13657.6 Ų57.664%0.63628%0.278SS*.  trans-132.4117.5174.5-70.5-178.4-169.400109.9K40E38-K40 PolarHBondContact O-N 2.93Å
39F92.1Very high89.1Confident10 Ų1056 Ų564%0.04427%0.272CS..  trans-68.7119.3174.8-64.9-79.3000110.3W31 I33 H37 K42 Q93 W111 E803 G806W31-F39 HydrophobicContact CZ2-CZ 4.2Å; I33-F39 HydrophobicContact CD1-CE1 4.42Å; I33-F39 HydrophobicContact CD1-CE2 3.81Å; I33-F39 HydrophobicContact CD1-CZ 3.48Å; I33-F39 VanDerWaalsContact CD1-CZ 3.48Å; H37-F39 AromaticContact NE2-CD1 3.69Å; H37-F39 AromaticContact NE2-CE1 3.83Å; F39-K42 PolarHBondContact O-NZ 3.44Å; F39-Q93 HydrophobicContact CD2-CB 3.66Å; F39-Q93 HydrophobicContact CD2-CG 4.22Å; F39-Q93 HydrophobicContact CE2-CB 4.17Å; F39-Q93 HydrophobicContact CG-CB 4.43Å; F39-W111 HydrophobicContact CE2-CZ2 4.22Å; F39-E803 WeakPolarHBondContact CE1-O 3.36Å; F39-G806 VanDerWaalsContact CD1-CA 3.47Å
40K87.3Confident88.2Confident202 Ų20257.6 Ų57.688%0.87828%0.281SS*.  trans-77.4-36.9-176.3-63.7-178.3-178.3175.50112.7E38 K42E38-K40 PolarHBondContact O-N 2.93Å; K40-K42 PolarHBondContact O-N 3.3Å
41E87.4Confident87Confident38 Ų3858.6 Ų58.618%0.17828%0.284CS..  trans-79.9122179.3-164.7177.3155.300109.5R43 Q93 R804 L805E41-R43 IonicContact OE1-CZ 3.18Å; E41-R43 IonicContact OE1-NE 2.58Å; E41-R43 PolarHBondContact OE1-NE 3.49Å; E41-R43 IonicContact OE1-NH2 3.58Å; E41-R43 PolarHBondContact OE1-NH2 3.12Å; E41-Q93 PolarHBondContact O-NE2 2.89Å; E41-Q93 VanDerWaalsContact O-NE2 3.1Å; E41-R804 HydrophobicContact CB-CG 4.5Å; E41-R804 VanDerWaalsContact OE2-CD 3.3Å; E41-R804 WeakPolarHBondContact OE2-CD 3.3Å; E41-R804 WeakPolarHBondContact OE2-CG 3.48Å; E41-R804 IonicContact OE2-NE 2.77Å; E41-R804 PolarHBondContact OE2-NE 3.19Å; E41-L805 HydrophobicContact CB-CD2 4.01Å; E41-L805 HydrophobicContact CG-CD2 3.69Å; E41-L805 WeakPolarHBondContact OE1-CD2 3.11Å; E41-L805 WeakPolarHBondContact OE2-CD2 3.24Å
42K85.6Confident85.7Confident131 Ų13160.8 Ų60.857%0.5730%0.3SS*.  trans-112.1132.9173.5-57.4-54.1-168-156.40108.3F39 K40F39-K42 PolarHBondContact O-NZ 3.44Å; K40-K42 PolarHBondContact O-N 3.3Å
43R88.3Confident84.3Confident16 Ų1667 Ų676%0.0633%0.334CS..  trans-117.2156.1177-64.8-170.5166.6-122.6-3.1111.2E41 L91 L805 M807 C816 N819 I820 Y821E41-R43 IonicContact OE1-CZ 3.18Å; E41-R43 IonicContact OE1-NE 2.58Å; E41-R43 PolarHBondContact OE1-NE 3.49Å; E41-R43 IonicContact OE1-NH2 3.58Å; E41-R43 PolarHBondContact OE1-NH2 3.12Å; R43-L91 HydrophobicContact CB-CD2 4.45Å; R43-L805 HydrophobicContact CG-CD2 4.09Å; R43-M807 HydrophobicContact CB-CE 4.38Å; R43-C816 PolarHBondContact NH1-O 2.48Å; R43-N819 VanDerWaalsContact CA-O 3.25Å; R43-N819 WeakPolarHBondContact CA-O 3.43Å; R43-N819 WeakPolarHBondContact CB-O 3.26Å; R43-I820 PolarHBondContact NH1-O 2.96Å; R43-Y821 HydrophobicContact CB-CD1 3.72Å; R43-Y821 HydrophobicContact CB-CE1 4.36Å
44K88.7Confident82.9Confident143 Ų14371 Ų7162%0.62236%0.363SS*.EExtended strand (participates in β ladder)trans-110.7149.2177.3-66.9179.2-176.6173.40109.6N819 I820 Y821K44-N819 PolarHBondContact N-O 2.89Å; K44-I820 VanDerWaalsContact O-CA 3.32Å; K44-I820 WeakPolarHBondContact O-CA 3.3Å; K44-Y821 WeakPolarHBondContact O-CD1 3.45Å; K44-Y821 PolarHBondContact O-N 3.11Å; K44-Y821 VanDerWaalsContact O-N 3.09Å
45P87.6Confident81.5Confident21 Ų2172.8 Ų72.814%0.13637%0.372CS..EExtended strand (participates in β ladder)trans-62.3149.117127.2-32.8000109.2Q47 A88 Y821P45-Q47 WeakPolarHBondContact O-CG 3.29Å; P45-Q47 PolarHBondContact O-N 3.33Å; P45-A88 HydrophobicContact CB-CB 3.59Å; P45-A88 HydrophobicContact CG-CB 3.81Å; P45-Y821 CarbonylContact C-O 3.39Å; P45-Y821 WeakPolarHBondContact CA-O 3.43Å; P45-Y821 HydrophobicContact CB-CE1 4.43Å; P45-Y821 HydrophobicContact CB-CE2 3.95Å; P45-Y821 WeakPolarHBondContact CD-OH 3.43Å; P45-Y821 VanDerWaalsContact N-CE1 3.34Å
46F82Confident80.3Confident53 Ų5375.6 Ų75.623%0.23239%0.389CS..  trans-57.9130.5171.9-175.1-88.7000110.4D50 V51 V764 I820 Y821 R822F46-D50 HydrophobicContact CD2-CB 4.12Å; F46-D50 HydrophobicContact CE2-CB 3.72Å; F46-D50 HydrophobicContact CZ-CB 4.11Å; F46-V51 HydrophobicContact CE1-CG2 4.02Å; F46-V51 HydrophobicContact CZ-CG2 3.85Å; F46-V764 HydrophobicContact CD2-CG1 3.78Å; F46-V764 HydrophobicContact CE1-CG2 4.3Å; F46-V764 HydrophobicContact CE2-CB 4.15Å; F46-V764 HydrophobicContact CE2-CG1 3.38Å; F46-V764 HydrophobicContact CE2-CG2 3.6Å; F46-V764 HydrophobicContact CZ-CB 4.21Å; F46-V764 HydrophobicContact CZ-CG1 3.82Å; F46-V764 HydrophobicContact CZ-CG2 3.36Å; F46-I820 HydrophobicContact CB-CG2 3.71Å; F46-I820 HydrophobicContact CD2-CG2 3.92Å; F46-I820 HydrophobicContact CG-CG2 4.32Å; F46-Y821 PolarHBondContact N-O 2.8Å; F46-R822 HydrophobicContact CB-CB 4.46Å
47Q78Confident79.1Confident82 Ų8279.8 Ų79.838%0.38341%0.413SS..  trans-124.6161.2-179.3-64.8-175.7-17.700111.6P45 K49 D50P45-Q47 WeakPolarHBondContact O-CG 3.29Å; P45-Q47 PolarHBondContact O-N 3.33Å; Q47-K49 HydrophobicContact CB-CG 4.21Å; Q47-K49 PolarHBondContact O-N 2.81Å; Q47-K49 VanDerWaalsContact OE1-CE 3.28Å; Q47-D50 WeakPolarHBondContact CA-OD2 3.32Å; Q47-D50 WeakPolarHBondContact CB-OD2 3.28Å; Q47-D50 PolarHBondContact N-OD2 3.24Å; Q47-D50 VanDerWaalsContact O-CB 3.3Å; Q47-D50 WeakPolarHBondContact O-CB 3.31Å; Q47-D50 PolarHBondContact O-N 3.39Å
48A68.5Low77.9Confident86 Ų8684.3 Ų84.371%0.71144%0.439SS*.G310 helixtrans-55.4-27.8178.900000114.3D50 V51A48-D50 PolarHBondContact O-N 2.85Å; A48-V51 WeakPolarHBondContact O-CB 3.18Å; A48-V51 WeakPolarHBondContact O-CG2 3.35Å; A48-V51 PolarHBondContact O-N 2.89Å
49K67.3Low77.3Confident142 Ų14281.3 Ų81.362%0.61743%0.425SS*.G310 helixtrans-71.8-16.4176.374.3-171.4-175.2-155.10113.7Q47 V51Q47-K49 HydrophobicContact CB-CG 4.21Å; Q47-K49 PolarHBondContact O-N 2.81Å; Q47-K49 VanDerWaalsContact OE1-CE 3.28Å; K49-V51 VanDerWaalsContact C-N 3.29Å
50D74Confident77Confident57 Ų5785.4 Ų85.431%0.30545%0.446SS..G310 helixtrans-87.5-5.7-179.7-51.9-46.7000111F46 Q47 A48 I820F46-D50 HydrophobicContact CD2-CB 4.12Å; F46-D50 HydrophobicContact CE2-CB 3.72Å; F46-D50 HydrophobicContact CZ-CB 4.11Å; Q47-D50 WeakPolarHBondContact CA-OD2 3.32Å; Q47-D50 WeakPolarHBondContact CB-OD2 3.28Å; Q47-D50 PolarHBondContact N-OD2 3.24Å; Q47-D50 VanDerWaalsContact O-CB 3.3Å; Q47-D50 WeakPolarHBondContact O-CB 3.31Å; Q47-D50 PolarHBondContact O-N 3.39Å; A48-D50 PolarHBondContact O-N 2.85Å; D50-I820 HydrophobicContact CB-CD1 4.1Å
51V70.6Confident77.1Confident35 Ų3577 Ų7721%0.21242%0.417CS..SBendtrans-72.5132.3169.5-177.40000109.6F46 A48 K49 N55 V56F46-V51 HydrophobicContact CE1-CG2 4.02Å; F46-V51 HydrophobicContact CZ-CG2 3.85Å; A48-V51 WeakPolarHBondContact O-CB 3.18Å; A48-V51 WeakPolarHBondContact O-CG2 3.35Å; A48-V51 PolarHBondContact O-N 2.89Å; K49-V51 VanDerWaalsContact C-N 3.29Å; V51-N55 HydrophobicContact CG1-CB 3.84Å; V51-V56 HydrophobicContact CG1-CG2 4.34Å
52S68.4Low77.2Confident49 Ų4976.1 Ų76.134%0.34341%0.413SS..  trans-61.1144.1178.965.50000112.1S54 N55 V56S52-S54 PolarHBondContact O-N 3.42Å; S52-S54 VanDerWaalsContact O-N 3.13Å; S52-S54 PolarHBondContact OG-OG 2.86Å; S52-N55 PolarHBondContact O-N 2.83Å; S52-N55 WeakPolarHBondContact OG-CB 3.45Å; S52-N55 PolarHBondContact OG-ND2 3.32Å; S52-V56 WeakPolarHBondContact O-CG2 3.47Å; S52-V56 PolarHBondContact O-N 2.87Å; S52-V56 VanDerWaalsContact O-N 3.09Å
53L68.4Low77.4Confident159 Ų15971.7 Ų71.783%0.83241%0.405SS*.Hα-helixtrans-56.5-31.3-179.2-73.6169.7000113.4N55 V56L53-N55 VanDerWaalsContact C-N 3.32Å; L53-V56 PolarHBondContact O-N 3.1Å
54S66.3Low77.6Confident85 Ų8575.5 Ų75.559%0.59443%0.425SS*.Hα-helixtrans-64.4-37174.956.70000112.1S52S52-S54 PolarHBondContact O-N 3.42Å; S52-S54 VanDerWaalsContact O-N 3.13Å; S52-S54 PolarHBondContact OG-OG 2.86Å
55N68.8Low77.9Confident37 Ų3771.7 Ų71.720%0.19841%0.407CS..Hα-helixtrans-85.2-20.1-177.6-65.25.5000111.7V51 S52 L53 V57 D58 H59 S762V51-N55 HydrophobicContact CG1-CB 3.84Å; S52-N55 PolarHBondContact O-N 2.83Å; S52-N55 WeakPolarHBondContact OG-CB 3.45Å; S52-N55 PolarHBondContact OG-ND2 3.32Å; L53-N55 VanDerWaalsContact C-N 3.32Å; N55-V57 VanDerWaalsContact C-N 3.31Å; N55-V57 PolarHBondContact O-N 2.99Å; N55-D58 PolarHBondContact O-N 3.09Å; N55-H59 PolarHBondContact O-N 2.7Å; N55-H59 PolarHBondContact O-ND1 2.79Å; N55-S762 PolarHBondContact ND2-O 2.66Å
56V72Confident78.3Confident60 Ų6070.9 Ų70.936%0.36440%0.401SS..Hα-helixtrans-56.9-43.4-179.6170.70000111.8V51 S52 L53 D58 H59 I60V51-V56 HydrophobicContact CG1-CG2 4.34Å; S52-V56 WeakPolarHBondContact O-CG2 3.47Å; S52-V56 PolarHBondContact O-N 2.87Å; S52-V56 VanDerWaalsContact O-N 3.09Å; L53-V56 PolarHBondContact O-N 3.1Å; V56-D58 VanDerWaalsContact C-N 3.34Å; V56-D58 PolarHBondContact O-N 2.83Å; V56-H59 PolarHBondContact O-N 2.9Å; V56-H59 VanDerWaalsContact O-N 3.13Å; V56-I60 VanDerWaalsContact O-CG1 3.31Å; V56-I60 WeakPolarHBondContact O-CG1 3.35Å; V56-I60 PolarHBondContact O-N 2.95Å; V56-I60 VanDerWaalsContact O-N 3.14Å
57V69.9Low78.8Confident102 Ų10272.8 Ų72.862%0.61841%0.413SS*.Hα-helixtrans-60.2-44.2-177.1178.40000111.3N55 H59 I60N55-V57 VanDerWaalsContact C-N 3.31Å; N55-V57 PolarHBondContact O-N 2.99Å; V57-H59 PolarHBondContact O-N 2.78Å; V57-I60 PolarHBondContact O-N 2.6Å
58D71.1Confident79.6Confident127 Ų12776.1 Ų76.168%0.67943%0.427SS*.Hα-helixtrans-68.2-25.7-180-63.7-25.8000112.3N55 V56N55-D58 PolarHBondContact O-N 3.09Å; V56-D58 VanDerWaalsContact C-N 3.34Å; V56-D58 PolarHBondContact O-N 2.83Å
59H81.2Confident80.9Confident73 Ų7373.7 Ų73.734%0.33840%0.399SS..Hα-helixtrans-98-1.2-176.5-65.775.1000114.1N55 V56 V57 G61 L62 G63N55-H59 PolarHBondContact O-N 2.7Å; N55-H59 PolarHBondContact O-ND1 2.79Å; V56-H59 PolarHBondContact O-N 2.9Å; V56-H59 VanDerWaalsContact O-N 3.13Å; V57-H59 PolarHBondContact O-N 2.78Å; H59-G61 VanDerWaalsContact C-N 3.29Å; H59-G61 PolarHBondContact O-N 3.16Å; H59-L62 WeakPolarHBondContact O-CB 3.46Å; H59-L62 PolarHBondContact O-N 2.89Å; H59-G63 PolarHBondContact O-N 3.05Å
60I85.5Confident82.2Confident95 Ų9568.4 Ų68.449%0.48738%0.375SS..Hα-helixtrans-58.3-44177.1-65.3178.4000110.8V56 V57 L62 G63 I64V56-I60 VanDerWaalsContact O-CG1 3.31Å; V56-I60 WeakPolarHBondContact O-CG1 3.35Å; V56-I60 PolarHBondContact O-N 2.95Å; V56-I60 VanDerWaalsContact O-N 3.14Å; V57-I60 PolarHBondContact O-N 2.6Å; I60-L62 VanDerWaalsContact C-N 3.35Å; I60-L62 PolarHBondContact O-N 2.92Å; I60-G63 PolarHBondContact O-N 3.37Å; I60-I64 HydrophobicContact CG2-CD1 4.01Å; I60-I64 WeakPolarHBondContact O-CG1 3.32Å; I60-I64 PolarHBondContact O-N 3.45Å
61G89.1Confident83.3Confident26 Ų2672.4 Ų72.427%0.26839%0.387SS..Hα-helixtrans-59.8-45.3178.800000112.1H59 R65H59-G61 VanDerWaalsContact C-N 3.29Å; H59-G61 PolarHBondContact O-N 3.16Å; G61-R65 WeakPolarHBondContact O-CG 3.34Å; G61-R65 PolarHBondContact O-N 2.84Å; G61-R65 VanDerWaalsContact O-N 3.16Å; G61-R65 PolarHBondContact O-NE 2.8Å; G61-R65 PolarHBondContact O-NH2 2.91Å
62L90.3Very high84.4Confident19 Ų1976.4 Ų76.410%0.09940%0.401CS..Hα-helixtrans-59.4-49.4173.8169.764.1000110.6H59 I60 I64 R65 Y66 L526 M527 I560H59-L62 WeakPolarHBondContact O-CB 3.46Å; H59-L62 PolarHBondContact O-N 2.89Å; I60-L62 VanDerWaalsContact C-N 3.35Å; I60-L62 PolarHBondContact O-N 2.92Å; L62-I64 VanDerWaalsContact C-N 3.35Å; L62-I64 PolarHBondContact O-N 2.95Å; L62-R65 PolarHBondContact O-N 3.47Å; L62-Y66 VanDerWaalsContact O-CB 3.24Å; L62-Y66 WeakPolarHBondContact O-CB 3.5Å; L62-Y66 PolarHBondContact O-N 2.94Å; L62-L526 HydrophobicContact CD1-CB 3.64Å; L62-L526 WeakPolarHBondContact CD1-O 3.34Å; L62-M527 HydrophobicContact CB-SD 4.46Å; L62-M527 HydrophobicContact CD2-CE 3.86Å; L62-M527 HydrophobicContact CD2-SD 4.06Å; L62-I560 HydrophobicContact CD1-CG2 4.37Å
63G89.8Confident85.6Confident39 Ų3975.9 Ų75.940%0.40239%0.393SS..Hα-helixtrans-57.3-43.4-178.200000113.3H59 I60 L67H59-G63 PolarHBondContact O-N 3.05Å; I60-G63 PolarHBondContact O-N 3.37Å; G63-L67 WeakPolarHBondContact O-CB 3.29Å; G63-L67 PolarHBondContact O-N 2.89Å
64I92.4Very high86.8Confident95 Ų9569 Ų6949%0.48736%0.358SS..Hα-helixtrans-65.6-46.1177-65.7170000111.1I60 L62 L67 K68I60-I64 HydrophobicContact CG2-CD1 4.01Å; I60-I64 WeakPolarHBondContact O-CG1 3.32Å; I60-I64 PolarHBondContact O-N 3.45Å; L62-I64 VanDerWaalsContact C-N 3.35Å; L62-I64 PolarHBondContact O-N 2.95Å; I64-L67 PolarHBondContact O-N 3.21Å; I64-K68 WeakPolarHBondContact O-CG 3.32Å; I64-K68 PolarHBondContact O-N 3.45Å; I64-K68 VanDerWaalsContact O-N 3.12Å
65R95.6Very high88.1Confident64 Ų6468.5 Ų68.524%0.24235%0.346CS..Hα-helixtrans-65.8-43.9179.9-74.1-176.1-68.7-93.41111.4G61 L62 K68 W69 L526 M527G61-R65 WeakPolarHBondContact O-CG 3.34Å; G61-R65 PolarHBondContact O-N 2.84Å; G61-R65 VanDerWaalsContact O-N 3.16Å; G61-R65 PolarHBondContact O-NE 2.8Å; G61-R65 PolarHBondContact O-NH2 2.91Å; L62-R65 PolarHBondContact O-N 3.47Å; R65-K68 PolarHBondContact O-N 3.14Å; R65-W69 WeakPolarHBondContact O-CB 3.43Å; R65-W69 PolarHBondContact O-N 3.44Å; R65-L526 HydrophobicContact CB-CD2 4.03Å; R65-L526 PolarHBondContact NE-O 3.37Å; R65-L526 PolarHBondContact NH2-O 3.46Å; R65-L526 VanDerWaalsContact NH2-O 3.1Å; R65-M527 PolarHBondContact NH2-O 2.76Å
66Y94.2Very high89.3Confident4 Ų471.3 Ų71.32%0.01637%0.365CS..Hα-helixtrans-61.7-44.7176.4-175.1-90000111.4L62 K68 W69 W70 I83 D84 M85 F86 L526 I560L62-Y66 VanDerWaalsContact O-CB 3.24Å; L62-Y66 WeakPolarHBondContact O-CB 3.5Å; L62-Y66 PolarHBondContact O-N 2.94Å; Y66-K68 VanDerWaalsContact C-N 3.35Å; Y66-K68 PolarHBondContact O-N 2.68Å; Y66-W69 HydrophobicContact CD2-CE3 4.06Å; Y66-W69 HydrophobicContact CD2-CZ3 4.31Å; Y66-W69 AromaticContact CE2-CE3 3.85Å; Y66-W69 HydrophobicContact CE2-CE3 3.85Å; Y66-W69 AromaticContact CE2-CZ3 3.64Å; Y66-W69 HydrophobicContact CE2-CZ3 3.64Å; Y66-W69 AromaticContact CZ-CZ3 3.99Å; Y66-W69 PolarHBondContact O-N 2.96Å; Y66-W70 HydrophobicContact CD1-CB 4.37Å; Y66-W70 HydrophobicContact CE1-CB 4.07Å; Y66-W70 HydrophobicContact CE1-CG 4.36Å; Y66-W70 WeakPolarHBondContact O-CB 3.49Å; Y66-W70 PolarHBondContact O-N 3.03Å; Y66-I83 PolarHBondContact OH-O 2.99Å; Y66-D84 WeakPolarHBondContact OH-CA 3.11Å; Y66-M85 HydrophobicContact CD1-SD 4.27Å; Y66-M85 HydrophobicContact CD2-CE 4.39Å; Y66-M85 HydrophobicContact CD2-SD 4.06Å; Y66-M85 HydrophobicContact CE1-CB 3.76Å; Y66-M85 HydrophobicContact CE1-CG 4.04Å; Y66-M85 HydrophobicContact CE1-SD 4.12Å; Y66-M85 HydrophobicContact CE2-CE 4.2Å; Y66-M85 HydrophobicContact CE2-CG 4.08Å; Y66-M85 HydrophobicContact CE2-SD 3.9Å; Y66-M85 HydrophobicContact CG-SD 4.25Å; Y66-M85 PolarHBondContact OH-N 2.92Å; Y66-F86 HydrophobicContact CD1-CD2 4.39Å; Y66-F86 AromaticContact CD1-CE2 3.57Å; Y66-F86 HydrophobicContact CD1-CE2 3.57Å; Y66-F86 AromaticContact CD1-CZ 3.93Å; Y66-F86 HydrophobicContact CD1-CZ 3.93Å; Y66-F86 AromaticContact CE1-CD2 3.76Å; Y66-F86 HydrophobicContact CE1-CD2 3.76Å; Y66-F86 AromaticContact CE1-CE2 3.39Å; Y66-F86 HydrophobicContact CE1-CE2 3.39Å; Y66-F86 HydrophobicContact CE1-CZ 4.09Å; Y66-L526 HydrophobicContact CD2-CD1 3.8Å; Y66-I560 HydrophobicContact CD2-CD1 4.27Å; Y66-I560 HydrophobicContact CE2-CD1 4.49Å
67L94.1Very high90.3Very high93 Ų9371.6 Ų71.649%0.48736%0.362SS..Hα-helixtrans-60.1-43.7176.4179.862.5000112.2G63 I64 Y71 F86G63-L67 WeakPolarHBondContact O-CB 3.29Å; G63-L67 PolarHBondContact O-N 2.89Å; I64-L67 PolarHBondContact O-N 3.21Å; L67-Y71 VanDerWaalsContact O-CB 3.28Å; L67-Y71 WeakPolarHBondContact O-CB 3.39Å; L67-Y71 PolarHBondContact O-N 3.35Å; L67-F86 HydrophobicContact CB-CZ 4.41Å; L67-F86 HydrophobicContact CD1-CE2 4.07Å; L67-F86 HydrophobicContact CD1-CZ 3.89Å
68K95.1Very high91.3Very high152 Ų15274.1 Ų74.166%0.66136%0.364SS*.Hα-helixtrans-62-46.6175.8-73.1179.1-179.6-177.70111.6I64 R65 Y66 K72I64-K68 WeakPolarHBondContact O-CG 3.32Å; I64-K68 PolarHBondContact O-N 3.45Å; I64-K68 VanDerWaalsContact O-N 3.12Å; R65-K68 PolarHBondContact O-N 3.14Å; Y66-K68 VanDerWaalsContact C-N 3.35Å; Y66-K68 PolarHBondContact O-N 2.68Å; K68-K72 WeakPolarHBondContact O-CB 3.43Å; K68-K72 PolarHBondContact O-N 2.87Å
69W95.3Very high92.3Very high34 Ų3470.2 Ų70.213%0.12934%0.342CS..Hα-helixtrans-62.9-48.5178172.287.7000111.8R65 Y66 Y71 K72 K73 P81 F82 L526 L559R65-W69 WeakPolarHBondContact O-CB 3.43Å; R65-W69 PolarHBondContact O-N 3.44Å; Y66-W69 HydrophobicContact CD2-CE3 4.06Å; Y66-W69 HydrophobicContact CD2-CZ3 4.31Å; Y66-W69 AromaticContact CE2-CE3 3.85Å; Y66-W69 HydrophobicContact CE2-CE3 3.85Å; Y66-W69 AromaticContact CE2-CZ3 3.64Å; Y66-W69 HydrophobicContact CE2-CZ3 3.64Å; Y66-W69 AromaticContact CZ-CZ3 3.99Å; Y66-W69 PolarHBondContact O-N 2.96Å; W69-Y71 VanDerWaalsContact C-N 3.34Å; W69-Y71 PolarHBondContact O-N 3.22Å; W69-K72 WeakPolarHBondContact O-CB 3.42Å; W69-K72 PolarHBondContact O-N 2.75Å; W69-K73 HydrophobicContact CD2-CG 4.16Å; W69-K73 HydrophobicContact CH2-CG 4.39Å; W69-K73 HydrophobicContact CZ2-CD 4.29Å; W69-K73 HydrophobicContact CZ2-CG 3.72Å; W69-K73 PolarHBondContact O-N 3.15Å; W69-P81 HydrophobicContact CH2-CB 3.69Å; W69-P81 HydrophobicContact CZ3-CB 3.87Å; W69-F82 AromaticContact CH2-CD1 3.4Å; W69-F82 HydrophobicContact CH2-CD1 3.4Å; W69-F82 AromaticContact CH2-CE1 3.32Å; W69-F82 HydrophobicContact CH2-CE1 3.32Å; W69-F82 HydrophobicContact CH2-CG 4.5Å; W69-F82 HydrophobicContact CH2-CZ 4.4Å; W69-F82 AromaticContact CZ2-CD1 3.43Å; W69-F82 HydrophobicContact CZ2-CD1 3.43Å; W69-F82 VanDerWaalsContact CZ2-CD1 3.43Å; W69-F82 AromaticContact CZ2-CE1 3.32Å; W69-F82 HydrophobicContact CZ2-CE1 3.32Å; W69-F82 HydrophobicContact CZ3-CE1 4.17Å; W69-L526 HydrophobicContact CB-CD1 4.2Å; W69-L526 HydrophobicContact CB-CD2 4.06Å; W69-L526 HydrophobicContact CD2-CD1 4.14Å; W69-L526 HydrophobicContact CE3-CD1 4.27Å; W69-L526 HydrophobicContact CG-CD1 4.1Å; W69-L526 HydrophobicContact CG-CD2 4.4Å; W69-L559 HydrophobicContact CD2-CD1 4.49Å; W69-L559 HydrophobicContact CZ2-CD2 4.37Å
70W95.2Very high92.7Very high31 Ų3168.5 Ų68.512%0.11734%0.34CS..Hα-helixtrans-61.4-41.7178.6178.894.2000111.6Y66 K73 T74 D84 F86Y66-W70 HydrophobicContact CD1-CB 4.37Å; Y66-W70 HydrophobicContact CE1-CB 4.07Å; Y66-W70 HydrophobicContact CE1-CG 4.36Å; Y66-W70 WeakPolarHBondContact O-CB 3.49Å; Y66-W70 PolarHBondContact O-N 3.03Å; W70-K73 PolarHBondContact O-N 2.86Å; W70-T74 HydrophobicContact CD2-CG2 4.18Å; W70-T74 HydrophobicContact CG-CG2 4.34Å; W70-T74 HydrophobicContact CZ2-CG2 4.22Å; W70-T74 WeakPolarHBondContact O-CB 3.31Å; W70-T74 WeakPolarHBondContact O-CG2 3.42Å; W70-T74 PolarHBondContact O-N 3.02Å; W70-T74 PolarHBondContact O-OG1 2.96Å; W70-D84 PolarHBondContact NE1-OD1 3Å; W70-D84 VanDerWaalsContact NE1-OD1 3.1Å; W70-D84 PolarHBondContact NE1-OD2 2.91Å; W70-F86 HydrophobicContact CB-CD2 4.32Å; W70-F86 HydrophobicContact CB-CE2 4Å; W70-F86 AromaticContact CD1-CD2 3.66Å; W70-F86 AromaticContact CD2-CD2 3.57Å; W70-F86 HydrophobicContact CD2-CD2 3.57Å; W70-F86 AromaticContact CD2-CE2 3.92Å; W70-F86 HydrophobicContact CD2-CE2 3.92Å; W70-F86 AromaticContact CE2-CD2 3.66Å; W70-F86 HydrophobicContact CE3-CD2 4.16Å; W70-F86 HydrophobicContact CE3-CE2 4.27Å; W70-F86 AromaticContact CG-CD2 3.61Å; W70-F86 HydrophobicContact CG-CD2 3.61Å; W70-F86 AromaticContact CG-CE2 3.78Å; W70-F86 HydrophobicContact CG-CE2 3.78Å; W70-F86 HydrophobicContact CZ2-CB 4.42Å; W70-F86 HydrophobicContact CZ2-CD2 4.33Å; W70-F86 AromaticContact NE1-CD2 3.68Å
71Y95.3Very high93Very high142 Ų14264.3 Ų64.356%0.55732%0.319SS*.Hα-helixtrans-62.2-46.6174.7-179.3-89.6000111L67 W69 Q75 V76L67-Y71 VanDerWaalsContact O-CB 3.28Å; L67-Y71 WeakPolarHBondContact O-CB 3.39Å; L67-Y71 PolarHBondContact O-N 3.35Å; W69-Y71 VanDerWaalsContact C-N 3.34Å; W69-Y71 PolarHBondContact O-N 3.22Å; Y71-Q75 HydrophobicContact CD1-CB 4.47Å; Y71-Q75 HydrophobicContact CD2-CB 4.04Å; Y71-Q75 HydrophobicContact CD2-CG 3.59Å; Y71-Q75 HydrophobicContact CE1-CB 4.31Å; Y71-Q75 HydrophobicContact CE2-CB 3.88Å; Y71-Q75 HydrophobicContact CE2-CG 3.67Å; Y71-Q75 HydrophobicContact CG-CB 4.34Å; Y71-Q75 HydrophobicContact CG-CG 4.2Å; Y71-Q75 WeakPolarHBondContact O-CA 3.37Å; Y71-Q75 WeakPolarHBondContact O-CB 3.37Å; Y71-Q75 PolarHBondContact O-N 2.94Å; Y71-V76 HydrophobicContact CE1-CG2 4.23Å; Y71-V76 PolarHBondContact O-N 3.31Å
72K94.8Very high93Very high118 Ų11863.3 Ų63.351%0.51331%0.307SS..Iπ-helixtrans-57.8-52.1175.7-172.2-169.5179.3-159.20110.9K68 W69 V76 E77K68-K72 WeakPolarHBondContact O-CB 3.43Å; K68-K72 PolarHBondContact O-N 2.87Å; W69-K72 WeakPolarHBondContact O-CB 3.42Å; W69-K72 PolarHBondContact O-N 2.75Å; K72-V76 WeakPolarHBondContact O-CA 3.4Å; K72-V76 VanDerWaalsContact O-CB 3.25Å; K72-V76 WeakPolarHBondContact O-CB 3.35Å; K72-V76 PolarHBondContact O-N 3.02Å; K72-V76 VanDerWaalsContact O-N 3.11Å; K72-E77 WeakPolarHBondContact CE-OE1 3.38Å; K72-E77 IonicContact NZ-OE1 3.46Å; K72-E77 PolarHBondContact NZ-OE1 2.93Å; K72-E77 PolarHBondContact O-N 2.85Å
73K93.3Very high93Very high38 Ų3863.3 Ų63.317%0.16531%0.307CS..Iπ-helixtrans-60.8-50.2-178.4-78.9-77.1169.6-165.70112.8W69 W70 E77 K78 K79W69-K73 HydrophobicContact CD2-CG 4.16Å; W69-K73 HydrophobicContact CH2-CG 4.39Å; W69-K73 HydrophobicContact CZ2-CD 4.29Å; W69-K73 HydrophobicContact CZ2-CG 3.72Å; W69-K73 PolarHBondContact O-N 3.15Å; W70-K73 PolarHBondContact O-N 2.86Å; K73-E77 VanDerWaalsContact CD-OE2 3.26Å; K73-E77 WeakPolarHBondContact CD-OE2 3.07Å; K73-E77 WeakPolarHBondContact CE-OE2 3.32Å; K73-E77 IonicContact NZ-OE2 2.85Å; K73-E77 PolarHBondContact NZ-OE2 3.27Å; K73-E77 CarbonylContact O-C 3.54Å; K73-E77 WeakPolarHBondContact O-CB 3.27Å; K73-K78 PolarHBondContact O-N 3.07Å; K73-K79 PolarHBondContact O-N 3.25Å
74T93.4Very high93Very high16 Ų1663 Ų6310%0.09830%0.296CS..Iπ-helixtrans-85.8-38.6-172.364.10000113.8W70 P81W70-T74 HydrophobicContact CD2-CG2 4.18Å; W70-T74 HydrophobicContact CG-CG2 4.34Å; W70-T74 HydrophobicContact CZ2-CG2 4.22Å; W70-T74 WeakPolarHBondContact O-CB 3.31Å; W70-T74 WeakPolarHBondContact O-CG2 3.42Å; W70-T74 PolarHBondContact O-N 3.02Å; W70-T74 PolarHBondContact O-OG1 2.96Å; T74-P81 HydrophobicContact CG2-CG 3.68Å
75Q93.9Very high92.6Very high73 Ų7363.1 Ų63.134%0.34130%0.296SS..Iπ-helixtrans-93.4-34-173.7-54.8-51.3-5200112.8Y71 K78Y71-Q75 HydrophobicContact CD1-CB 4.47Å; Y71-Q75 HydrophobicContact CD2-CB 4.04Å; Y71-Q75 HydrophobicContact CD2-CG 3.59Å; Y71-Q75 HydrophobicContact CE1-CB 4.31Å; Y71-Q75 HydrophobicContact CE2-CB 3.88Å; Y71-Q75 HydrophobicContact CE2-CG 3.67Å; Y71-Q75 HydrophobicContact CG-CB 4.34Å; Y71-Q75 HydrophobicContact CG-CG 4.2Å; Y71-Q75 WeakPolarHBondContact O-CA 3.37Å; Y71-Q75 WeakPolarHBondContact O-CB 3.37Å; Y71-Q75 PolarHBondContact O-N 2.94Å; Q75-K78 WeakPolarHBondContact O-CE 3.3Å; Q75-K78 PolarHBondContact O-NZ 2.71Å
76V94.4Very high92.1Very high97 Ų9765.2 Ų65.259%0.58831%0.307SS*.Iπ-helixtrans-95.6-56.5-179.6-174.40000110.9Y71 K72 K78Y71-V76 HydrophobicContact CE1-CG2 4.23Å; Y71-V76 PolarHBondContact O-N 3.31Å; K72-V76 WeakPolarHBondContact O-CA 3.4Å; K72-V76 VanDerWaalsContact O-CB 3.25Å; K72-V76 WeakPolarHBondContact O-CB 3.35Å; K72-V76 PolarHBondContact O-N 3.02Å; K72-V76 VanDerWaalsContact O-N 3.11Å; V76-K78 VanDerWaalsContact C-N 3.35Å
77E92.4Very high91.7Very high65 Ų6572.6 Ų72.630%0.30434%0.335SS..SBendtrans-80.4-15.3-175.2-60.7175.1-160.900113.2K72 K73 K79K72-E77 WeakPolarHBondContact CE-OE1 3.38Å; K72-E77 IonicContact NZ-OE1 3.46Å; K72-E77 PolarHBondContact NZ-OE1 2.93Å; K72-E77 PolarHBondContact O-N 2.85Å; K73-E77 VanDerWaalsContact CD-OE2 3.26Å; K73-E77 WeakPolarHBondContact CD-OE2 3.07Å; K73-E77 WeakPolarHBondContact CE-OE2 3.32Å; K73-E77 IonicContact NZ-OE2 2.85Å; K73-E77 PolarHBondContact NZ-OE2 3.27Å; K73-E77 CarbonylContact O-C 3.54Å; K73-E77 WeakPolarHBondContact O-CB 3.27Å; E77-K79 HydrophobicContact CB-CG 4.28Å; E77-K79 PolarHBondContact O-N 3.08Å
78K91.7Very high91.3Very high155 Ų15569.9 Ų69.967%0.67433%0.326SS*.  trans56.826.5-176.8-54.4-54-168.7-164.90114.1K73 Q75 V76K73-K78 PolarHBondContact O-N 3.07Å; Q75-K78 WeakPolarHBondContact O-CE 3.3Å; Q75-K78 PolarHBondContact O-NZ 2.71Å; V76-K78 VanDerWaalsContact C-N 3.35Å
79K90.8Very high91Very high46 Ų4664.5 Ų64.520%0.230%0.304CS..PPolyproline II helixtrans-96.2153.6174.2-63.4-169177.4-143.30110.6K73 E77 D548 D549K73-K79 PolarHBondContact O-N 3.25Å; E77-K79 HydrophobicContact CB-CG 4.28Å; E77-K79 PolarHBondContact O-N 3.08Å; K79-D548 HydrophobicContact CB-CB 4.4Å; K79-D548 HydrophobicContact CD-CB 4.43Å; K79-D548 PolarHBondContact NZ-O 3.46Å; K79-D549 IonicContact NZ-OD1 2.91Å; K79-D549 PolarHBondContact NZ-OD1 3.5Å
80A90.1Very high90.6Very high36 Ų3666.5 Ų66.530%0.29832%0.321SS..PPolyproline II helixtrans-76.9152.5169.200000110.2R481 D548A80-R481 PolarHBondContact O-NH2 3.46Å; A80-D548 WeakPolarHBondContact CB-OD2 3.15Å; A80-D548 PolarHBondContact N-OD2 2.7Å
81P91.1Very high90.5Very high7 Ų766.5 Ų66.55%0.04532%0.323CS..PPolyproline II helixtrans-71.4145.1172.5-21.336.2000112.1W69 T74 I83 D84 R481W69-P81 HydrophobicContact CH2-CB 3.69Å; W69-P81 HydrophobicContact CZ3-CB 3.87Å; T74-P81 HydrophobicContact CG2-CG 3.68Å; P81-I83 WeakPolarHBondContact CB-O 3.34Å; P81-I83 PolarHBondContact O-N 3.43Å; P81-D84 HydrophobicContact CB-CB 4.03Å; P81-D84 HydrophobicContact CG-CB 3.92Å; P81-R481 PolarHBondContact O-NE 3.24Å; P81-R481 PolarHBondContact O-NH2 3.46Å
82F89.1Confident90.5Very high5 Ų564.1 Ų64.12%0.02231%0.313CS..SBendtrans-61.3-34.4171.968.4-87.2000111.6W69 Y480 R481 M482 Y558 L559 I560W69-F82 AromaticContact CH2-CD1 3.4Å; W69-F82 HydrophobicContact CH2-CD1 3.4Å; W69-F82 AromaticContact CH2-CE1 3.32Å; W69-F82 HydrophobicContact CH2-CE1 3.32Å; W69-F82 HydrophobicContact CH2-CG 4.5Å; W69-F82 HydrophobicContact CH2-CZ 4.4Å; W69-F82 AromaticContact CZ2-CD1 3.43Å; W69-F82 HydrophobicContact CZ2-CD1 3.43Å; W69-F82 VanDerWaalsContact CZ2-CD1 3.43Å; W69-F82 AromaticContact CZ2-CE1 3.32Å; W69-F82 HydrophobicContact CZ2-CE1 3.32Å; W69-F82 HydrophobicContact CZ3-CE1 4.17Å; F82-Y480 CarbonylContact O-C 3.5Å; F82-Y480 WeakPolarHBondContact O-CA 3.36Å; F82-R481 PolarHBondContact O-N 2.99Å; F82-M482 HydrophobicContact CB-CG 4.24Å; F82-M482 HydrophobicContact CD2-CE 4.07Å; F82-M482 HydrophobicContact CD2-CG 4.32Å; F82-M482 HydrophobicContact CD2-SD 3.64Å; F82-M482 HydrophobicContact CE2-SD 4.31Å; F82-Y558 AromaticContact CE2-CD2 4Å; F82-Y558 HydrophobicContact CE2-CD2 4Å; F82-L559 HydrophobicContact CE1-CD1 3.88Å; F82-L559 HydrophobicContact CE1-CD2 4.11Å; F82-L559 HydrophobicContact CE1-CG 3.61Å; F82-L559 HydrophobicContact CZ-CD1 4.12Å; F82-L559 HydrophobicContact CZ-CG 3.94Å; F82-I560 HydrophobicContact CE2-CG1 4.19Å; F82-I560 HydrophobicContact CZ-CD1 3.97Å; F82-I560 HydrophobicContact CZ-CG1 3.98Å
83I91.1Very high90.5Very high19 Ų1959.6 Ų59.610%0.09729%0.294CS..BIsolated β-bridgetrans-132.2121165.5-63.8171.6000107Y66 P81 M85 Y480 M482Y66-I83 PolarHBondContact OH-O 2.99Å; P81-I83 WeakPolarHBondContact CB-O 3.34Å; P81-I83 PolarHBondContact O-N 3.43Å; I83-M85 HydrophobicContact CG2-CG 4.17Å; I83-Y480 HydrophobicContact CB-CD1 4.34Å; I83-Y480 HydrophobicContact CD1-CD1 4.21Å; I83-Y480 HydrophobicContact CD1-CE1 4.48Å; I83-Y480 HydrophobicContact CD1-CG 4.36Å; I83-Y480 HydrophobicContact CG1-CD1 3.68Å; I83-Y480 HydrophobicContact CG1-CE1 4.24Å; I83-Y480 HydrophobicContact CG1-CG 4.06Å; I83-Y480 HydrophobicContact CG2-CD1 4.03Å; I83-Y480 HydrophobicContact CG2-CE1 3.88Å; I83-M482 HydrophobicContact CD1-CE 3.98Å; I83-M482 HydrophobicContact CG1-CE 3.9Å
84D89.9Confident90.6Very high32 Ų3259.6 Ų59.617%0.17130%0.296CS..  trans-102.192.8176.9-164.8-24.6000111.7Y66 W70 P81 F86 R87Y66-D84 WeakPolarHBondContact OH-CA 3.11Å; W70-D84 PolarHBondContact NE1-OD1 3Å; W70-D84 VanDerWaalsContact NE1-OD1 3.1Å; W70-D84 PolarHBondContact NE1-OD2 2.91Å; P81-D84 HydrophobicContact CB-CB 4.03Å; P81-D84 HydrophobicContact CG-CB 3.92Å; D84-F86 PolarHBondContact O-N 3.47Å; D84-F86 PolarHBondContact OD1-N 3.41Å; D84-R87 PolarHBondContact O-N 3.46Å; D84-R87 PolarHBondContact OD1-N 2.99Å
85M84.6Confident90.8Very high99 Ų9959.2 Ų59.249%0.48829%0.292SS..THydrogen-bonded Turntrans-69.4-13.5179.8-60.7-179.5178.500113.4Y66 I83 I560Y66-M85 HydrophobicContact CD1-SD 4.27Å; Y66-M85 HydrophobicContact CD2-CE 4.39Å; Y66-M85 HydrophobicContact CD2-SD 4.06Å; Y66-M85 HydrophobicContact CE1-CB 3.76Å; Y66-M85 HydrophobicContact CE1-CG 4.04Å; Y66-M85 HydrophobicContact CE1-SD 4.12Å; Y66-M85 HydrophobicContact CE2-CE 4.2Å; Y66-M85 HydrophobicContact CE2-CG 4.08Å; Y66-M85 HydrophobicContact CE2-SD 3.9Å; Y66-M85 HydrophobicContact CG-SD 4.25Å; Y66-M85 PolarHBondContact OH-N 2.92Å; I83-M85 HydrophobicContact CG2-CG 4.17Å; M85-I560 HydrophobicContact CE-CD1 4.12Å
86F84.8Confident91Very high108 Ų10855.8 Ų55.847%0.47428%0.276SS..THydrogen-bonded Turntrans-97.8-22.9179.6-62-63.1000112.8Y66 L67 W70 D84Y66-F86 HydrophobicContact CD1-CD2 4.39Å; Y66-F86 AromaticContact CD1-CE2 3.57Å; Y66-F86 HydrophobicContact CD1-CE2 3.57Å; Y66-F86 AromaticContact CD1-CZ 3.93Å; Y66-F86 HydrophobicContact CD1-CZ 3.93Å; Y66-F86 AromaticContact CE1-CD2 3.76Å; Y66-F86 HydrophobicContact CE1-CD2 3.76Å; Y66-F86 AromaticContact CE1-CE2 3.39Å; Y66-F86 HydrophobicContact CE1-CE2 3.39Å; Y66-F86 HydrophobicContact CE1-CZ 4.09Å; L67-F86 HydrophobicContact CB-CZ 4.41Å; L67-F86 HydrophobicContact CD1-CE2 4.07Å; L67-F86 HydrophobicContact CD1-CZ 3.89Å; W70-F86 HydrophobicContact CB-CD2 4.32Å; W70-F86 HydrophobicContact CB-CE2 4Å; W70-F86 AromaticContact CD1-CD2 3.66Å; W70-F86 AromaticContact CD2-CD2 3.57Å; W70-F86 HydrophobicContact CD2-CD2 3.57Å; W70-F86 AromaticContact CD2-CE2 3.92Å; W70-F86 HydrophobicContact CD2-CE2 3.92Å; W70-F86 AromaticContact CE2-CD2 3.66Å; W70-F86 HydrophobicContact CE3-CD2 4.16Å; W70-F86 HydrophobicContact CE3-CE2 4.27Å; W70-F86 AromaticContact CG-CD2 3.61Å; W70-F86 HydrophobicContact CG-CD2 3.61Å; W70-F86 AromaticContact CG-CE2 3.78Å; W70-F86 HydrophobicContact CG-CE2 3.78Å; W70-F86 HydrophobicContact CZ2-CB 4.42Å; W70-F86 HydrophobicContact CZ2-CD2 4.33Å; W70-F86 AromaticContact NE1-CD2 3.68Å; D84-F86 PolarHBondContact O-N 3.47Å; D84-F86 PolarHBondContact OD1-N 3.41Å
87R85.8Confident91.2Very high159 Ų15951.1 Ų51.160%0.625%0.248SC*.SBendtrans-131.358-175.2-57.4179.2177.5175.91.1111.8D84D84-R87 PolarHBondContact O-N 3.46Å; D84-R87 PolarHBondContact OD1-N 2.99Å
88A85.4Confident91.5Very high36 Ų3648 Ų4830%0.29823%0.234SC..PPolyproline II helixtrans-55.3144.8172.800000111.9P45 E479P45-A88 HydrophobicContact CB-CB 3.59Å; P45-A88 HydrophobicContact CG-CB 3.81Å; A88-E479 WeakPolarHBondContact CA-OE1 3.32Å
89L88.1Confident91.8Very high38 Ų3840.7 Ų40.720%0.19920%0.202CC..PPolyproline II helixtrans-71.5127.2177.1-69.8175.9000109.5Y127 Q478 E479 Y821 L824L89-Y127 HydrophobicContact CD1-CE1 4.2Å; L89-Y127 HydrophobicContact CD1-CE2 3.87Å; L89-Y127 VanDerWaalsContact CD1-CZ 3.5Å; L89-Y127 WeakPolarHBondContact CD1-OH 3.43Å; L89-Y127 HydrophobicContact CD2-CD2 3.92Å; L89-Y127 HydrophobicContact CD2-CE2 3.51Å; L89-Y127 HydrophobicContact CG-CE2 4.39Å; L89-Q478 HydrophobicContact CD1-CB 4.13Å; L89-E479 HydrophobicContact CB-CG 3.88Å; L89-E479 HydrophobicContact CD1-CG 3.63Å; L89-E479 HydrophobicContact CG-CG 3.82Å; L89-E479 PolarHBondContact N-OE1 3.3Å; L89-Y821 PolarHBondContact O-OH 3.21Å; L89-L824 HydrophobicContact CB-CD1 4.49Å
90P88.4Confident92.2Very high76 Ų7638.5 Ų38.549%0.49419%0.192SC..PPolyproline II helixtrans-71.5135.3176.529.1-33.3000110.1R92P90-R92 WeakPolarHBondContact O-CG 3.36Å; P90-R92 PolarHBondContact O-N 2.86Å
91L92.7Very high92.6Very high32 Ų3236.8 Ų36.817%0.16818%0.178CC..PPolyproline II helixtrans-56.5123.3170.6173.363.7000110.3R43 Q93 M807 Q810 Y821 L824R43-L91 HydrophobicContact CB-CD2 4.45Å; L91-Q93 HydrophobicContact CD1-CG 4.42Å; L91-Q93 HydrophobicContact CD2-CG 4.32Å; L91-Q93 HydrophobicContact CG-CG 4.15Å; L91-M807 HydrophobicContact CD1-CE 4.16Å; L91-M807 HydrophobicContact CD1-CG 3.69Å; L91-M807 HydrophobicContact CD2-CE 3.67Å; L91-M807 HydrophobicContact CD2-CG 4.45Å; L91-Q810 HydrophobicContact CD1-CG 4.46Å; L91-Y821 HydrophobicContact CB-CE1 3.62Å; L91-Y821 HydrophobicContact CD2-CE1 4.35Å; L91-Y821 PolarHBondContact N-OH 3.38Å; L91-L824 HydrophobicContact CB-CD1 4.39Å; L91-L824 HydrophobicContact CD1-CD2 3.99Å
92R93.8Very high93Very high91 Ų9136.4 Ų36.434%0.34318%0.176SC..  trans-122.3107.4174.6-58.9-168.9-173.4-175.69.5109.9P90 I94 Y95 Y127 Q810P90-R92 WeakPolarHBondContact O-CG 3.36Å; P90-R92 PolarHBondContact O-N 2.86Å; R92-I94 HydrophobicContact CB-CD1 4.19Å; R92-I94 HydrophobicContact CB-CG1 3.97Å; R92-I94 PolarHBondContact O-N 3.36Å; R92-Y95 HydrophobicContact CB-CE2 3.98Å; R92-Y95 WeakPolarHBondContact O-CD2 3.44Å; R92-Y127 PolarHBondContact NH1-O 3.15Å; R92-Q810 PolarHBondContact O-NE2 3.21Å; R92-Q810 PolarHBondContact O-OE1 3.44Å
93Q95.3Very high93.4Very high23 Ų2336.3 Ų36.311%0.10718%0.176CC..THydrogen-bonded Turntrans-78.350.3-175.5-61.2162.4-49.100112.2F39 E41 L91 W111 L805 G806F39-Q93 HydrophobicContact CD2-CB 3.66Å; F39-Q93 HydrophobicContact CD2-CG 4.22Å; F39-Q93 HydrophobicContact CE2-CB 4.17Å; F39-Q93 HydrophobicContact CG-CB 4.43Å; E41-Q93 PolarHBondContact O-NE2 2.89Å; E41-Q93 VanDerWaalsContact O-NE2 3.1Å; L91-Q93 HydrophobicContact CD1-CG 4.42Å; L91-Q93 HydrophobicContact CD2-CG 4.32Å; L91-Q93 HydrophobicContact CG-CG 4.15Å; Q93-W111 PolarHBondContact O-NE1 3.26Å; Q93-L805 PolarHBondContact NE2-O 2.92Å; Q93-G806 WeakPolarHBondContact CG-O 3.25Å
94I96Very high93.6Very high39 Ų3935.4 Ų35.420%0.217%0.172CC..THydrogen-bonded Turntrans-125.8-13.8-171.468.5176.9000113.5R92 G110 W111 C116R92-I94 HydrophobicContact CB-CD1 4.19Å; R92-I94 HydrophobicContact CB-CG1 3.97Å; R92-I94 PolarHBondContact O-N 3.36Å; I94-G110 CarbonylContact O-C 3.57Å; I94-G110 WeakPolarHBondContact O-CA 3.39Å; I94-W111 VanDerWaalsContact C-CD1 3.4Å; I94-W111 VanDerWaalsContact O-CD1 3.27Å; I94-W111 PolarHBondContact O-N 3.33Å; I94-C116 HydrophobicContact CD1-CB 3.98Å
95Y97.8Very high94Very high8 Ų833.9 Ų33.93%0.03116%0.163CC..  trans-74.9144.5-170.1-59.2-57.4000113R92 T108 C116 R117 Q810R92-Y95 HydrophobicContact CB-CE2 3.98Å; R92-Y95 WeakPolarHBondContact O-CD2 3.44Å; Y95-T108 HydrophobicContact CD1-CG2 4.18Å; Y95-C116 VanDerWaalsContact CD1-SG 3.54Å; Y95-R117 HydrophobicContact CD1-CB 4.22Å; Y95-R117 HydrophobicContact CE1-CB 3.77Å; Y95-Q810 HydrophobicContact CD2-CB 4.03Å; Y95-Q810 VanDerWaalsContact CD2-CD 3.44Å; Y95-Q810 HydrophobicContact CD2-CG 4.16Å
96G98.3Very high94.6Very high0 Ų029.2 Ų29.20%014%0.14CC..  trans-123-172.517400000110.4T108 R109 F809G96-T108 WeakPolarHBondContact O-CG2 3.38Å; G96-R109 VanDerWaalsContact CA-O 3.31Å; G96-R109 WeakPolarHBondContact CA-O 3.43Å; G96-R109 PolarHBondContact N-O 2.69Å; G96-F809 VanDerWaalsContact C-CG 3.41Å; G96-F809 VanDerWaalsContact CA-CD2 3.4Å; G96-F809 WeakPolarHBondContact O-CB 3.37Å; G96-F809 VanDerWaalsContact O-CG 3.26Å; G96-F809 WeakPolarHBondContact O-CG 3.43Å
97A98.5Very high95.3Very high0 Ų024 Ų240%012%0.118CC..PPolyproline II helixtrans-57.7129176.800000111.4Y173 Y177 A180 Q197 F809A97-Y173 WeakPolarHBondContact CB-OH 3.27Å; A97-Y173 PolarHBondContact N-OH 3.31Å; A97-Y177 HydrophobicContact CB-CD2 4.22Å; A97-A180 HydrophobicContact CB-CB 4Å; A97-Q197 PolarHBondContact O-NE2 3Å; A97-Q197 VanDerWaalsContact O-NE2 3.1Å; A97-F809 HydrophobicContact CB-CE1 3.94Å; A97-F809 HydrophobicContact CB-CZ 3.96Å
98P98.4Very high95.9Very high0 Ų016.5 Ų16.50%09%0.089CC..EExtended strand (participates in β ladder)trans-71.714918029.8-34.4000112.2Y177 S199 Y430 D434P98-Y177 HydrophobicContact CG-CD2 4.43Å; P98-Y177 HydrophobicContact CG-CE2 3.82Å; P98-S199 PolarHBondContact O-OG 3.14Å; P98-Y430 HydrophobicContact CG-CD2 4.27Å; P98-D434 HydrophobicContact CB-CB 3.73Å; P98-D434 HydrophobicContact CG-CB 3.66Å
99L98.8Very high96.5Very high0 Ų014.9 Ų14.90%08%0.075CC..EExtended strand (participates in β ladder)trans-94.6139.2175.5-54.3171000110T106 I107 R109 F115 Q197 S199 A214 F216 W357L99-T106 VanDerWaalsContact O-CA 3.24Å; L99-T106 WeakPolarHBondContact O-CA 3.24Å; L99-T106 WeakPolarHBondContact O-CB 3.46Å; L99-I107 WeakPolarHBondContact CA-O 3.5Å; L99-I107 WeakPolarHBondContact CB-O 3.44Å; L99-I107 VanDerWaalsContact CG-O 3.27Å; L99-I107 WeakPolarHBondContact CG-O 3.31Å; L99-I107 PolarHBondContact N-O 3.27Å; L99-I107 PolarHBondContact O-N 3.45Å; L99-R109 HydrophobicContact CD1-CB 4.25Å; L99-F115 HydrophobicContact CD1-CE1 3.91Å; L99-Q197 HydrophobicContact CD2-CB 4.03Å; L99-Q197 HydrophobicContact CD2-CG 4.41Å; L99-S199 VanDerWaalsContact CA-OG 3.32Å; L99-S199 WeakPolarHBondContact CA-OG 3.46Å; L99-A214 HydrophobicContact CB-CB 3.83Å; L99-A214 HydrophobicContact CD2-CB 3.86Å; L99-A214 HydrophobicContact CG-CB 4.28Å; L99-F216 HydrophobicContact CD1-CE1 4.17Å; L99-F216 HydrophobicContact CD1-CZ 3.58Å; L99-F216 HydrophobicContact CD2-CE1 4.23Å; L99-F216 HydrophobicContact CD2-CZ 4.25Å; L99-W357 HydrophobicContact CB-CH2 4.34Å
100G98.3Very high96.9Very high0 Ų013.1 Ų13.10%07%0.066CC..SBendtrans113.3159.4175.600000114.6S199G100-S199 PolarHBondContact N-OG 2.97Å; G100-S199 VanDerWaalsContact N-OG 3.14Å
101G98.2Very high97.4Very high0 Ų09.8 Ų9.80%04%0.044CC..  trans-77.4170.1172.100000113.7G103 G104 S209 L211G101-G103 PolarHBondContact O-N 3.02Å; G101-G104 PolarHBondContact O-N 3.22Å; G101-S209 CarbonylContact C-O 3.48Å; G101-S209 VanDerWaalsContact CA-O 3.29Å; G101-S209 WeakPolarHBondContact CA-O 3.3Å; G101-L211 WeakPolarHBondContact CA-O 3.42Å; G101-L211 PolarHBondContact N-O 2.92Å
102I98.7Very high97.6Very high0 Ų010.5 Ų10.50%04%0.044CC..THydrogen-bonded Turntrans-60.4121.6175.2-55.6179.1000110.1G104 V201 S209 S210 V432 T437 W439 F472 W500 L503I102-G104 PolarHBondContact O-N 3.16Å; I102-G104 VanDerWaalsContact O-N 3.11Å; I102-V201 HydrophobicContact CD1-CG1 4.2Å; I102-V201 HydrophobicContact CG1-CG1 4.24Å; I102-V201 HydrophobicContact CG1-CG2 4.29Å; I102-S209 WeakPolarHBondContact CA-O 3.39Å; I102-S209 WeakPolarHBondContact CB-O 3.4Å; I102-S209 PolarHBondContact N-O 3.02Å; I102-S210 WeakPolarHBondContact O-CA 3.37Å; I102-V432 HydrophobicContact CD1-CG1 3.76Å; I102-V432 HydrophobicContact CG1-CG1 4.09Å; I102-V432 HydrophobicContact CG2-CG1 4.39Å; I102-T437 HydrophobicContact CG2-CG2 3.88Å; I102-W439 HydrophobicContact CB-CE3 4.18Å; I102-W439 HydrophobicContact CB-CZ3 4.43Å; I102-W439 HydrophobicContact CG2-CE3 4.01Å; I102-F472 HydrophobicContact CG2-CD2 4.43Å; I102-F472 HydrophobicContact CG2-CE2 3.43Å; I102-F472 VanDerWaalsContact CG2-CE2 3.43Å; I102-F472 HydrophobicContact CG2-CZ 4.07Å; I102-W500 HydrophobicContact CD1-CD2 3.94Å; I102-W500 HydrophobicContact CD1-CE3 4.4Å; I102-W500 HydrophobicContact CD1-CG 4.43Å; I102-W500 HydrophobicContact CD1-CH2 4.28Å; I102-W500 HydrophobicContact CD1-CZ2 3.81Å; I102-L503 HydrophobicContact CG2-CD1 4.41Å
103G97.9Very high97.6Very high2 Ų26.1 Ų6.12%0.0213%0.028CC..THydrogen-bonded Turntrans74.1-6.3175.700000115.7G101 G105 R373G101-G103 PolarHBondContact O-N 3.02Å; G103-G105 PolarHBondContact O-N 2.88Å; G103-R373 PolarHBondContact O-NH1 3.05Å
104G96.1Very high97.7Very high1 Ų15.4 Ų5.41%0.012%0.024CC..SBendtrans-75.6-7.8170.500000113.8G101 I102 W357 R373G101-G104 PolarHBondContact O-N 3.22Å; I102-G104 PolarHBondContact O-N 3.16Å; I102-G104 VanDerWaalsContact O-N 3.11Å; G104-W357 PolarHBondContact O-NE1 2.76Å; G104-R373 PolarHBondContact O-NH1 3.39Å
105G97.3Very high97.8Very high0 Ų03.5 Ų3.50%02%0.015CC..  trans83.4158.6-168.100000110G103 Q119 W357G103-G105 PolarHBondContact O-N 2.88Å; G105-Q119 CarbonylContact C-O 3.59Å; G105-Q119 WeakPolarHBondContact CA-O 3.3Å; G105-W357 WeakPolarHBondContact O-CZ2 3.36Å; G105-W357 PolarHBondContact O-NE1 2.54Å
106T98.5Very high97.7Very high0 Ų03.1 Ų3.10%01%0.013CC..EExtended strand (participates in β ladder)trans-132.6154.7-174.9570000113.5L99 Q119 A433 D434L99-T106 VanDerWaalsContact O-CA 3.24Å; L99-T106 WeakPolarHBondContact O-CA 3.24Å; L99-T106 WeakPolarHBondContact O-CB 3.46Å; T106-Q119 PolarHBondContact N-O 3.31Å; T106-Q119 PolarHBondContact O-N 3.12Å; T106-A433 HydrophobicContact CG2-CB 3.88Å; T106-A433 WeakPolarHBondContact CG2-O 3.24Å; T106-D434 HydrophobicContact CG2-CB 4.35Å; T106-D434 PolarHBondContact OG1-OD1 2.92Å
107I98.6Very high97.7Very high0 Ų03.1 Ų3.10%01%0.013CC..EExtended strand (participates in β ladder)trans-127.7115.1173-55.3171.5000107.8L99 F115 W118 L120 L355 W357L99-I107 WeakPolarHBondContact CA-O 3.5Å; L99-I107 WeakPolarHBondContact CB-O 3.44Å; L99-I107 VanDerWaalsContact CG-O 3.27Å; L99-I107 WeakPolarHBondContact CG-O 3.31Å; L99-I107 PolarHBondContact N-O 3.27Å; L99-I107 PolarHBondContact O-N 3.45Å; I107-F115 HydrophobicContact CG2-CD1 3.8Å; I107-W118 HydrophobicContact CB-CE3 4.35Å; I107-W118 HydrophobicContact CB-CZ3 4.49Å; I107-W118 HydrophobicContact CD1-CE3 3.94Å; I107-W118 HydrophobicContact CD1-CZ3 3.58Å; I107-W118 HydrophobicContact CG1-CE3 3.72Å; I107-W118 HydrophobicContact CG1-CZ3 3.89Å; I107-W118 HydrophobicContact CG2-CD2 4.08Å; I107-W118 HydrophobicContact CG2-CE3 3.79Å; I107-W118 HydrophobicContact CG2-CH2 4Å; I107-W118 HydrophobicContact CG2-CZ2 4.25Å; I107-W118 HydrophobicContact CG2-CZ3 3.77Å; I107-L120 HydrophobicContact CD1-CD2 4.31Å; I107-L120 HydrophobicContact CG1-CD2 3.95Å; I107-L355 HydrophobicContact CD1-CD2 3.9Å; I107-W357 HydrophobicContact CD1-CD2 4.07Å; I107-W357 HydrophobicContact CD1-CE3 3.66Å; I107-W357 HydrophobicContact CD1-CH2 4.44Å; I107-W357 HydrophobicContact CD1-CZ3 3.87Å; I107-W357 HydrophobicContact CG1-CE3 4.48Å; I107-W357 HydrophobicContact CG1-CZ3 4.44Å
108T98.4Very high97.6Very high0 Ų03.1 Ų3.10%01%0.013CC..EExtended strand (participates in β ladder)trans-84.6122.4178.4-440000110.8Y95 G96 C116 R117 D434Y95-T108 HydrophobicContact CD1-CG2 4.18Å; G96-T108 WeakPolarHBondContact O-CG2 3.38Å; T108-C116 PolarHBondContact O-N 3.09Å; T108-R117 PolarHBondContact N-O 3.35Å; T108-R117 PolarHBondContact OG1-NE 3.3Å; T108-D434 PolarHBondContact OG1-OD2 2.78Å
109R97.8Very high97.5Very high2 Ų23.1 Ų3.11%0.0081%0.013CC..EExtended strand (participates in β ladder)trans-95.6121.7164.7-168.8178.1179.8-135.50.7109G96 L99 G113 E114G96-R109 VanDerWaalsContact CA-O 3.31Å; G96-R109 WeakPolarHBondContact CA-O 3.43Å; G96-R109 PolarHBondContact N-O 2.69Å; L99-R109 HydrophobicContact CD1-CB 4.25Å; R109-G113 PolarHBondContact NE-O 3.31Å; R109-G113 VanDerWaalsContact NE-O 3.11Å; R109-E114 CarbonylContact C-O 3.46Å; R109-E114 WeakPolarHBondContact CA-O 3.49Å
110G97.8Very high97.3Very high1 Ų13.5 Ų3.51%0.012%0.015CC..PPolyproline II helixtrans-65159.9179.800000112.6I94 R112 G113 E114I94-G110 CarbonylContact O-C 3.57Å; I94-G110 WeakPolarHBondContact O-CA 3.39Å; G110-R112 PolarHBondContact O-N 3.32Å; G110-R112 VanDerWaalsContact O-N 3.12Å; G110-G113 WeakPolarHBondContact O-CA 3.39Å; G110-G113 PolarHBondContact O-N 3.15Å; G110-E114 PolarHBondContact N-O 3.16Å
111W97.5Very high97.2Very high6 Ų65.5 Ų5.52%0.0233%0.026CC..THydrogen-bonded Turntrans-67.4-11-179.962-94.7000113.3W31 I33 C34 L35 H37 F39 Q93 I94 Y173W31-W111 HydrophobicContact CH2-CB 4.4Å; W31-W111 HydrophobicContact CH2-CG 4.23Å; W31-W111 HydrophobicContact CZ3-CB 4.23Å; I33-W111 HydrophobicContact CD1-CD2 4.35Å; I33-W111 HydrophobicContact CD1-CE3 4.27Å; I33-W111 HydrophobicContact CD1-CH2 4.18Å; I33-W111 HydrophobicContact CD1-CZ2 4.32Å; I33-W111 HydrophobicContact CD1-CZ3 4.17Å; I33-W111 HydrophobicContact CG1-CE3 4.34Å; I33-W111 HydrophobicContact CG1-CZ3 4.21Å; I33-W111 HydrophobicContact CG2-CB 4.25Å; I33-W111 HydrophobicContact CG2-CD2 4.18Å; I33-W111 HydrophobicContact CG2-CE3 3.89Å; I33-W111 HydrophobicContact CG2-CG 4.35Å; C34-W111 VanDerWaalsContact O-CZ3 3.32Å; C34-W111 WeakPolarHBondContact O-CZ3 3.42Å; L35-W111 WeakPolarHBondContact CD1-O 3.48Å; H37-W111 HydrophobicContact CB-CH2 4.31Å; H37-W111 WeakPolarHBondContact O-CH2 3.49Å; F39-W111 HydrophobicContact CE2-CZ2 4.22Å; Q93-W111 PolarHBondContact O-NE1 3.26Å; I94-W111 VanDerWaalsContact C-CD1 3.4Å; I94-W111 VanDerWaalsContact O-CD1 3.27Å; I94-W111 PolarHBondContact O-N 3.33Å; W111-Y173 HydrophobicContact CB-CD1 3.42Å; W111-Y173 VanDerWaalsContact CB-CD1 3.42Å; W111-Y173 HydrophobicContact CB-CD2 4.17Å; W111-Y173 HydrophobicContact CB-CE1 3.87Å; W111-Y173 HydrophobicContact CB-CG 3.58Å; W111-Y173 VanDerWaalsContact O-CB 3.28Å; W111-Y173 WeakPolarHBondContact O-CB 3.39Å
112R96.9Very high96.9Very high47 Ų475.7 Ų5.718%0.1773%0.027CC..THydrogen-bonded Turntrans-99.45.6170.4-73.5174.3175.5-141.20.5113.5L35 H37 G110 E114 V153L35-R112 HydrophobicContact CG-CG 4.33Å; L35-R112 VanDerWaalsContact O-CZ 3.25Å; L35-R112 PolarHBondContact O-NE 2.52Å; L35-R112 VanDerWaalsContact O-NE 3.16Å; L35-R112 PolarHBondContact O-NH2 3.38Å; H37-R112 PolarHBondContact O-NH2 2.92Å; G110-R112 PolarHBondContact O-N 3.32Å; G110-R112 VanDerWaalsContact O-N 3.12Å; R112-E114 VanDerWaalsContact CB-CD 3.48Å; R112-E114 WeakPolarHBondContact CB-OE1 3.43Å; R112-E114 WeakPolarHBondContact CB-OE2 3.18Å; R112-V153 HydrophobicContact CB-CG2 4.17Å; R112-V153 HydrophobicContact CG-CG2 4.14Å
113G95.5Very high96.7Very high0 Ų05.7 Ų5.70%03%0.027CC..SBendtrans98.81172.200000115.3R109 G110R109-G113 PolarHBondContact NE-O 3.31Å; R109-G113 VanDerWaalsContact NE-O 3.11Å; G110-G113 WeakPolarHBondContact O-CA 3.39Å; G110-G113 PolarHBondContact O-N 3.15Å
114E95.9Very high96.4Very high7 Ų78.1 Ų8.13%0.0334%0.039CC..  trans-86.8137.4-173.2-36.990149.500113.3R109 G110 R112 C116 T129 E154R109-E114 CarbonylContact C-O 3.46Å; R109-E114 WeakPolarHBondContact CA-O 3.49Å; G110-E114 PolarHBondContact N-O 3.16Å; R112-E114 VanDerWaalsContact CB-CD 3.48Å; R112-E114 WeakPolarHBondContact CB-OE1 3.43Å; R112-E114 WeakPolarHBondContact CB-OE2 3.18Å; E114-C116 PolarHBondContact O-N 2.83Å; E114-T129 HydrophobicContact CB-CG2 3.59Å; E114-T129 HydrophobicContact CG-CG2 4.21Å; E114-E154 HydrophobicContact CG-CG 4.32Å
115F97.9Very high96.3Very high0 Ų09.2 Ų9.20%04%0.043CC..EExtended strand (participates in β ladder)trans-79.6105171.6-64.7-98.3000109.8L99 I107 W118 T129 V130 N133 F135 F216 F234 L355L99-F115 HydrophobicContact CD1-CE1 3.91Å; I107-F115 HydrophobicContact CG2-CD1 3.8Å; F115-W118 HydrophobicContact CB-CH2 4.48Å; F115-W118 HydrophobicContact CB-CZ2 3.81Å; F115-T129 WeakPolarHBondContact O-CA 3.39Å; F115-V130 PolarHBondContact O-N 2.84Å; F115-N133 HydrophobicContact CB-CB 4.05Å; F115-N133 HydrophobicContact CD2-CB 3.45Å; F115-N133 VanDerWaalsContact CD2-CB 3.45Å; F115-N133 WeakPolarHBondContact CD2-O 3.29Å; F115-N133 HydrophobicContact CE2-CB 4.09Å; F115-N133 HydrophobicContact CG-CB 3.89Å; F115-F135 HydrophobicContact CZ-CE2 4.49Å; F115-F216 HydrophobicContact CE1-CZ 4.33Å; F115-F216 HydrophobicContact CZ-CZ 4.23Å; F115-F234 HydrophobicContact CE2-CE2 4.09Å; F115-F234 AromaticContact CZ-CE2 3.79Å; F115-F234 HydrophobicContact CZ-CE2 3.79Å; F115-F234 AromaticContact CZ-CZ 3.97Å; F115-F234 HydrophobicContact CZ-CZ 3.97Å; F115-L355 HydrophobicContact CE1-CD2 4.11Å
116C96.6Very high96.1Very high0 Ų010.8 Ų10.80%05%0.05CC..EExtended strand (participates in β ladder)trans-131.2-10.8-156.5660000117I94 Y95 T108 E114 Y127I94-C116 HydrophobicContact CD1-CB 3.98Å; Y95-C116 VanDerWaalsContact CD1-SG 3.54Å; T108-C116 PolarHBondContact O-N 3.09Å; E114-C116 PolarHBondContact O-N 2.83Å; C116-Y127 CarbonylContact O-C 3.54Å
117R97.4Very high95.9Very high0 Ų012.9 Ų12.90%06%0.058CC..EExtended strand (participates in β ladder)trans-141.7137.2170.1174.1172.869.7-156-8.7109.7Y95 T108 Y125 H126 Y127 D434 F809Y95-R117 HydrophobicContact CD1-CB 4.22Å; Y95-R117 HydrophobicContact CE1-CB 3.77Å; T108-R117 PolarHBondContact N-O 3.35Å; T108-R117 PolarHBondContact OG1-NE 3.3Å; R117-Y125 HydrophobicContact CG-CD1 3.9Å; R117-H126 CarbonylContact C-O 3.37Å; R117-H126 WeakPolarHBondContact CA-O 3.24Å; R117-Y127 HydrophobicContact CG-CD1 4.14Å; R117-Y127 HydrophobicContact CG-CE1 4.22Å; R117-D434 IonicContact CZ-OD2 3.57Å; R117-D434 IonicContact NE-OD1 2.78Å; R117-D434 IonicContact NE-OD2 3.97Å; R117-D434 PolarHBondContact NE-OD2 2.6Å; R117-D434 IonicContact NH2-OD2 3.82Å; R117-D434 PolarHBondContact NH2-OD2 3.15Å; R117-F809 PolarHBondContact NH1-O 2.87Å; R117-F809 PolarHBondContact NH2-O 2.8Å
118W97.4Very high95.6Very high0 Ų018.4 Ų18.40%08%0.082CC..EExtended strand (participates in β ladder)trans-131.6121.6-173.2-55.177.2000109.4I107 F115 L120 Y125 H126 K128 V130 N133 M236 S240I107-W118 HydrophobicContact CB-CE3 4.35Å; I107-W118 HydrophobicContact CB-CZ3 4.49Å; I107-W118 HydrophobicContact CD1-CE3 3.94Å; I107-W118 HydrophobicContact CD1-CZ3 3.58Å; I107-W118 HydrophobicContact CG1-CE3 3.72Å; I107-W118 HydrophobicContact CG1-CZ3 3.89Å; I107-W118 HydrophobicContact CG2-CD2 4.08Å; I107-W118 HydrophobicContact CG2-CE3 3.79Å; I107-W118 HydrophobicContact CG2-CH2 4Å; I107-W118 HydrophobicContact CG2-CZ2 4.25Å; I107-W118 HydrophobicContact CG2-CZ3 3.77Å; F115-W118 HydrophobicContact CB-CH2 4.48Å; F115-W118 HydrophobicContact CB-CZ2 3.81Å; W118-L120 HydrophobicContact CE3-CD1 4.3Å; W118-Y125 CarbonylContact O-C 3.52Å; W118-Y125 WeakPolarHBondContact O-CA 3.37Å; W118-H126 HydrophobicContact CB-CB 4.28Å; W118-H126 PolarHBondContact N-O 2.92Å; W118-H126 PolarHBondContact O-N 2.79Å; W118-K128 PolarHBondContact NE1-O 3.46Å; W118-V130 HydrophobicContact CZ2-CB 4.08Å; W118-V130 HydrophobicContact CZ2-CG2 3.57Å; W118-N133 VanDerWaalsContact CH2-ND2 3.31Å; W118-N133 WeakPolarHBondContact CH2-ND2 3.38Å; W118-N133 WeakPolarHBondContact CZ2-ND2 3.33Å; W118-M236 HydrophobicContact CH2-CE 3.77Å; W118-M236 HydrophobicContact CZ3-CE 4.32Å; W118-S240 VanDerWaalsContact CD1-O 3.32Å; W118-S240 PolarHBondContact NE1-O 3.16Å
119Q95.9Very high95.4Very high0 Ų020.2 Ų20.20%09%0.093CC..EExtended strand (participates in β ladder)trans-122.361.7174.9-170.8-90.4-4200108.3G105 T106 N121 Y125G105-Q119 CarbonylContact C-O 3.59Å; G105-Q119 WeakPolarHBondContact CA-O 3.3Å; T106-Q119 PolarHBondContact N-O 3.31Å; T106-Q119 PolarHBondContact O-N 3.12Å; Q119-N121 PolarHBondContact NE2-O 2.9Å; Q119-Y125 HydrophobicContact CB-CD1 3.82Å; Q119-Y125 HydrophobicContact CB-CE1 3.67Å; Q119-Y125 HydrophobicContact CG-CD1 4.11Å; Q119-Y125 HydrophobicContact CG-CE1 3.71Å; Q119-Y125 HydrophobicContact CG-CE2 4.26Å
120L95.4Very high95.4Very high8 Ų820.6 Ų20.64%0.04210%0.096CC..  trans-84.1-37.6174.8-60.6-173.4000110.8I107 W118 Y278 L280 W357 M359 R373I107-L120 HydrophobicContact CD1-CD2 4.31Å; I107-L120 HydrophobicContact CG1-CD2 3.95Å; W118-L120 HydrophobicContact CE3-CD1 4.3Å; L120-Y278 HydrophobicContact CD1-CD2 4.09Å; L120-Y278 HydrophobicContact CD1-CE1 4.23Å; L120-Y278 HydrophobicContact CD1-CE2 3.56Å; L120-L280 HydrophobicContact CD1-CD2 4.33Å; L120-W357 HydrophobicContact CD2-CD2 4.34Å; L120-W357 HydrophobicContact CD2-CG 4Å; L120-M359 HydrophobicContact CB-CE 4.05Å; L120-M359 VanDerWaalsContact O-SD 3.33Å; L120-R373 PolarHBondContact O-NH2 2.88Å
121N94.6Very high95.2Very high42 Ų4222.5 Ų22.523%0.22511%0.105CC..SBendtrans-80.9141.4174.5-77.8-54.2000110.9Q119 G123 M124 N276Q119-N121 PolarHBondContact NE2-O 2.9Å; N121-G123 PolarHBondContact O-N 2.84Å; N121-G123 VanDerWaalsContact O-N 3.12Å; N121-M124 HydrophobicContact CB-CB 3.96Å; N121-M124 PolarHBondContact O-N 3.5Å; N121-M124 VanDerWaalsContact O-N 3.08Å; N121-N276 WeakPolarHBondContact OD1-CB 3.39Å; N121-N276 PolarHBondContact OD1-ND2 3.19Å
122P93.8Very high95.1Very high4 Ų422.6 Ų22.63%0.02611%0.107CC..THydrogen-bonded Turntrans-48.5116.1178.7-31.438.2000113.1M124 I362 F364 V438P122-M124 WeakPolarHBondContact O-CG 3.28Å; P122-M124 PolarHBondContact O-N 3.31Å; P122-I362 HydrophobicContact CB-CD1 4.39Å; P122-I362 HydrophobicContact CG-CB 3.87Å; P122-I362 HydrophobicContact CG-CD1 3.52Å; P122-I362 HydrophobicContact CG-CG1 4.23Å; P122-I362 HydrophobicContact CG-CG2 4.1Å; P122-F364 HydrophobicContact CB-CD1 3.74Å; P122-F364 HydrophobicContact CB-CE1 3.57Å; P122-F364 HydrophobicContact CB-CZ 4.47Å; P122-V438 HydrophobicContact CB-CG1 3.69Å; P122-V438 HydrophobicContact CG-CG1 4.43Å
123G92.9Very high95.2Very high0 Ų020.3 Ų20.30%010%0.099CC..THydrogen-bonded Turntrans62.36.2179.200000116.9N121 G436 Y483N121-G123 PolarHBondContact O-N 2.84Å; N121-G123 VanDerWaalsContact O-N 3.12Å; G123-G436 PolarHBondContact N-O 3.13Å; G123-Y483 WeakPolarHBondContact CA-OH 3.44Å; G123-Y483 PolarHBondContact N-OH 3.37Å
124M93Very high95.3Very high52 Ų5220.4 Ų20.426%0.25610%0.099SC..  trans-114.9133.6-175.3-62.9-57.3-82.500111.6N121 P122 R481 P547N121-M124 HydrophobicContact CB-CB 3.96Å; N121-M124 PolarHBondContact O-N 3.5Å; N121-M124 VanDerWaalsContact O-N 3.08Å; P122-M124 WeakPolarHBondContact O-CG 3.28Å; P122-M124 PolarHBondContact O-N 3.31Å; M124-R481 PolarHBondContact SD-NH1 3.24Å; M124-P547 HydrophobicContact SD-CB 4.29Å; M124-P547 HydrophobicContact SD-CG 4.16Å
125Y94.1Very high95.4Very high25 Ų2520.1 Ų20.110%0.09810%0.098CC..  trans-115.1146.5-173.3-67.5-96.2000113.7R117 W118 Q119 Y127 D434 G435 G436 L475 Q478R117-Y125 HydrophobicContact CG-CD1 3.9Å; W118-Y125 CarbonylContact O-C 3.52Å; W118-Y125 WeakPolarHBondContact O-CA 3.37Å; Q119-Y125 HydrophobicContact CB-CD1 3.82Å; Q119-Y125 HydrophobicContact CB-CE1 3.67Å; Q119-Y125 HydrophobicContact CG-CD1 4.11Å; Q119-Y125 HydrophobicContact CG-CE1 3.71Å; Q119-Y125 HydrophobicContact CG-CE2 4.26Å; Y125-Y127 VanDerWaalsContact CB-CZ 3.43Å; Y125-Y127 WeakPolarHBondContact CB-OH 3.42Å; Y125-Y127 HydrophobicContact CG-CE1 4.46Å; Y125-Y127 AromaticContact CG-CZ 3.99Å; Y125-D434 PolarHBondContact OH-O 2.96Å; Y125-G435 VanDerWaalsContact OH-C 3.24Å; Y125-G436 WeakPolarHBondContact OH-CA 3.34Å; Y125-G436 PolarHBondContact OH-N 2.8Å; Y125-L475 HydrophobicContact CE2-CD1 3.92Å; Y125-Q478 HydrophobicContact CD1-CG 4.42Å; Y125-Q478 HydrophobicContact CD2-CG 4.3Å; Y125-Q478 HydrophobicContact CE1-CG 3.9Å; Y125-Q478 HydrophobicContact CE2-CG 3.78Å; Y125-Q478 PolarHBondContact OH-NE2 3.29Å
126H92.7Very high95.5Very high33 Ų3320.1 Ų20.115%0.15310%0.098CC..BIsolated β-bridgetrans-121.4118.5163.8-54.3-42.4000110R117 W118 K128 S240 H242R117-H126 CarbonylContact C-O 3.37Å; R117-H126 WeakPolarHBondContact CA-O 3.24Å; W118-H126 HydrophobicContact CB-CB 4.28Å; W118-H126 PolarHBondContact N-O 2.92Å; W118-H126 PolarHBondContact O-N 2.79Å; H126-K128 VanDerWaalsContact C-N 3.3Å; H126-K128 PolarHBondContact O-N 2.96Å; H126-S240 PolarHBondContact CD2-OG 3.24Å; H126-H242 AromaticContact CD2-CG 3.96Å; H126-H242 AromaticContact CE1-CD2 3.3Å; H126-H242 PolarHBondContact CE1-CD2 2.86Å; H126-H242 AromaticContact CE1-CE1 3.73Å; H126-H242 AromaticContact CE1-CG 3.55Å; H126-H242 AromaticContact CE1-ND1 3.82Å; H126-H242 AromaticContact CE1-NE2 3.5Å; H126-H242 PolarHBondContact CE1-NE2 3.09Å; H126-H242 AromaticContact CG-CD2 3.85Å; H126-H242 AromaticContact ND1-CD2 3.32Å; H126-H242 PolarHBondContact ND1-CD2 2.84Å; H126-H242 VanDerWaalsContact ND1-CD2 3.32Å; H126-H242 AromaticContact ND1-CG 3.87Å; H126-H242 AromaticContact ND1-NE2 3.8Å; H126-H242 AromaticContact NE2-CD2 3.83Å; H126-H242 AromaticContact NE2-CG 3.6Å; H126-H242 AromaticContact NE2-ND1 3.87Å
127Y93.4Very high95.6Very high43 Ų4320.1 Ų20.117%0.16910%0.098CC..  trans-92.523.7-175.4-57.6-80000113.2L89 R92 C116 R117 Y125 Q478L89-Y127 HydrophobicContact CD1-CE1 4.2Å; L89-Y127 HydrophobicContact CD1-CE2 3.87Å; L89-Y127 VanDerWaalsContact CD1-CZ 3.5Å; L89-Y127 WeakPolarHBondContact CD1-OH 3.43Å; L89-Y127 HydrophobicContact CD2-CD2 3.92Å; L89-Y127 HydrophobicContact CD2-CE2 3.51Å; L89-Y127 HydrophobicContact CG-CE2 4.39Å; R92-Y127 PolarHBondContact NH1-O 3.15Å; C116-Y127 CarbonylContact O-C 3.54Å; R117-Y127 HydrophobicContact CG-CD1 4.14Å; R117-Y127 HydrophobicContact CG-CE1 4.22Å; Y125-Y127 VanDerWaalsContact CB-CZ 3.43Å; Y125-Y127 WeakPolarHBondContact CB-OH 3.42Å; Y125-Y127 HydrophobicContact CG-CE1 4.46Å; Y125-Y127 AromaticContact CG-CZ 3.99Å; Y127-Q478 WeakPolarHBondContact OH-CB 3.45Å
128K92.5Very high95.6Very high117 Ų11720.1 Ų20.151%0.50910%0.098SC..  trans-95.1129.1-172.8-164.1-176.6-177.61730110.8W118 H126 V130 G241W118-K128 PolarHBondContact NE1-O 3.46Å; H126-K128 VanDerWaalsContact C-N 3.3Å; H126-K128 PolarHBondContact O-N 2.96Å; K128-V130 PolarHBondContact O-N 3.46Å; K128-G241 WeakPolarHBondContact CD-O 3.49Å; K128-G241 PolarHBondContact NZ-O 3.19Å
129T95.3Very high95.7Very high37 Ų3720.1 Ų20.123%0.22710%0.098CC..  trans-66.3121.1166.9-530000110.8E114 F115 I131E114-T129 HydrophobicContact CB-CG2 3.59Å; E114-T129 HydrophobicContact CG-CG2 4.21Å; F115-T129 WeakPolarHBondContact O-CA 3.39Å; T129-I131 HydrophobicContact CG2-CD1 3.91Å; T129-I131 PolarHBondContact O-N 2.79Å
130V96.1Very high95.8Very high10 Ų1021.2 Ų21.26%0.06110%0.102CC..  trans-93.888.3174.3-171.50000108.4F115 W118 K128 A132 N133 V237 S240F115-V130 PolarHBondContact O-N 2.84Å; W118-V130 HydrophobicContact CZ2-CB 4.08Å; W118-V130 HydrophobicContact CZ2-CG2 3.57Å; K128-V130 PolarHBondContact O-N 3.46Å; V130-A132 PolarHBondContact O-N 3.28Å; V130-A132 VanDerWaalsContact O-N 3.1Å; V130-N133 HydrophobicContact CB-CB 4.41Å; V130-N133 HydrophobicContact CG1-CB 4.42Å; V130-N133 VanDerWaalsContact CG1-CG 3.49Å; V130-N133 VanDerWaalsContact CG1-OD1 3.24Å; V130-N133 WeakPolarHBondContact CG1-OD1 3.33Å; V130-N133 WeakPolarHBondContact O-CB 3.39Å; V130-N133 PolarHBondContact O-N 2.86Å; V130-V237 HydrophobicContact CG1-CB 3.92Å; V130-V237 HydrophobicContact CG1-CG2 3.66Å; V130-S240 WeakPolarHBondContact CG2-O 3.35Å
131I94.6Very high95.8Very high41 Ų4126.7 Ų26.721%0.2112%0.122CC..THydrogen-bonded Turntrans-52.7-35.6-172.8-68.5-63000113.9T129 N133 Q134 P156 L159 W164T129-I131 HydrophobicContact CG2-CD1 3.91Å; T129-I131 PolarHBondContact O-N 2.79Å; I131-N133 PolarHBondContact O-N 2.84Å; I131-Q134 VanDerWaalsContact O-CG 3.27Å; I131-Q134 WeakPolarHBondContact O-CG 3.2Å; I131-Q134 PolarHBondContact O-NE2 2.89Å; I131-P156 HydrophobicContact CG1-CB 4.44Å; I131-P156 HydrophobicContact CG2-CB 3.4Å; I131-P156 HydrophobicContact CG2-CG 3.6Å; I131-L159 HydrophobicContact CG2-CD1 4.25Å; I131-W164 HydrophobicContact CG2-CH2 4.08Å; I131-W164 HydrophobicContact CG2-CZ2 4.42Å
132A96.1Very high95.8Very high8 Ų828.5 Ų28.57%0.06615%0.151CC..THydrogen-bonded Turntrans-73.2-10.2-178.500000113.8V130 Q134 L159 T235 V237 P300V130-A132 PolarHBondContact O-N 3.28Å; V130-A132 VanDerWaalsContact O-N 3.1Å; A132-Q134 PolarHBondContact O-N 2.84Å; A132-L159 HydrophobicContact CB-CD1 3.83Å; A132-T235 WeakPolarHBondContact O-CB 3.3Å; A132-T235 PolarHBondContact O-OG1 3.48Å; A132-V237 HydrophobicContact CB-CG2 3.69Å; A132-P300 HydrophobicContact CB-CB 3.96Å
133N98.1Very high95.7Very high0 Ų030.5 Ų30.50%017%0.172CC..  trans-85.6105177.1-637.2000108.7F115 W118 V130 I131 T235 M236 V237F115-N133 HydrophobicContact CB-CB 4.05Å; F115-N133 HydrophobicContact CD2-CB 3.45Å; F115-N133 VanDerWaalsContact CD2-CB 3.45Å; F115-N133 WeakPolarHBondContact CD2-O 3.29Å; F115-N133 HydrophobicContact CE2-CB 4.09Å; F115-N133 HydrophobicContact CG-CB 3.89Å; W118-N133 VanDerWaalsContact CH2-ND2 3.31Å; W118-N133 WeakPolarHBondContact CH2-ND2 3.38Å; W118-N133 WeakPolarHBondContact CZ2-ND2 3.33Å; V130-N133 HydrophobicContact CB-CB 4.41Å; V130-N133 HydrophobicContact CG1-CB 4.42Å; V130-N133 VanDerWaalsContact CG1-CG 3.49Å; V130-N133 VanDerWaalsContact CG1-OD1 3.24Å; V130-N133 WeakPolarHBondContact CG1-OD1 3.33Å; V130-N133 WeakPolarHBondContact O-CB 3.39Å; V130-N133 PolarHBondContact O-N 2.86Å; I131-N133 PolarHBondContact O-N 2.84Å; N133-T235 WeakPolarHBondContact CA-O 3.36Å; N133-M236 HydrophobicContact CB-SD 3.51Å; N133-M236 VanDerWaalsContact CB-SD 3.51Å; N133-M236 PolarHBondContact ND2-SD 2.98Å; N133-M236 WeakPolarHBondContact OD1-CA 3.35Å; N133-V237 PolarHBondContact OD1-N 2.85Å
134Q97.7Very high95.8Very high1 Ų137.6 Ų37.61%0.00521%0.205CC..EExtended strand (participates in β ladder)trans-150.1160.2-168.5-65.9-61-18.700113.1I131 A132 V150 W164 F234 T235I131-Q134 VanDerWaalsContact O-CG 3.27Å; I131-Q134 WeakPolarHBondContact O-CG 3.2Å; I131-Q134 PolarHBondContact O-NE2 2.89Å; A132-Q134 PolarHBondContact O-N 2.84Å; Q134-V150 HydrophobicContact CB-CG1 4.14Å; Q134-V150 HydrophobicContact CG-CG1 4.02Å; Q134-W164 HydrophobicContact CG-CH2 3.58Å; Q134-W164 HydrophobicContact CG-CZ3 4.09Å; Q134-F234 WeakPolarHBondContact O-CA 3.41Å; Q134-F234 WeakPolarHBondContact O-CD2 3.5Å; Q134-T235 PolarHBondContact N-O 2.94Å; Q134-T235 PolarHBondContact N-OG1 2.99Å; Q134-T235 PolarHBondContact O-N 3.45Å; Q134-T235 PolarHBondContact O-OG1 3.1Å
135F98.8Very high96.1Very high1 Ų136.9 Ų36.90%0.00420%0.204CC..EExtended strand (participates in β ladder)trans-104.4138.2158.3-70.2-85.2000110.4F115 L151 F216 W218 I232 M233 F234 F353F115-F135 HydrophobicContact CZ-CE2 4.49Å; F135-L151 HydrophobicContact CB-CD1 4.35Å; F135-L151 WeakPolarHBondContact O-CB 3.39Å; F135-L151 PolarHBondContact O-N 2.95Å; F135-F216 HydrophobicContact CE2-CD1 4.06Å; F135-F216 HydrophobicContact CE2-CD2 4.43Å; F135-F216 HydrophobicContact CE2-CE1 4.21Å; F135-F216 HydrophobicContact CE2-CG 4.15Å; F135-F216 HydrophobicContact CE2-CZ 4.44Å; F135-F216 HydrophobicContact CZ-CB 3.97Å; F135-F216 HydrophobicContact CZ-CD1 4.06Å; F135-F216 AromaticContact CZ-CD2 3.8Å; F135-F216 HydrophobicContact CZ-CD2 3.8Å; F135-F216 HydrophobicContact CZ-CE1 4.49Å; F135-F216 HydrophobicContact CZ-CE2 4.25Å; F135-F216 AromaticContact CZ-CG 3.68Å; F135-F216 HydrophobicContact CZ-CG 3.68Å; F135-W218 HydrophobicContact CB-CH2 4.12Å; F135-W218 HydrophobicContact CB-CZ2 3.52Å; F135-W218 AromaticContact CD1-CE2 3.81Å; F135-W218 AromaticContact CD1-CZ2 3.78Å; F135-W218 HydrophobicContact CD1-CZ2 3.78Å; F135-W218 AromaticContact CD1-NE1 3.4Å; F135-W218 AromaticContact CD2-CZ2 3.79Å; F135-W218 HydrophobicContact CD2-CZ2 3.79Å; F135-W218 HydrophobicContact CE1-CZ2 4.41Å; F135-W218 AromaticContact CE1-NE1 3.34Å; F135-W218 VanDerWaalsContact CE1-NE1 3.34Å; F135-W218 HydrophobicContact CE2-CZ2 4.42Å; F135-W218 AromaticContact CG-CE2 3.95Å; F135-W218 HydrophobicContact CG-CH2 4.45Å; F135-W218 AromaticContact CG-CZ2 3.42Å; F135-W218 HydrophobicContact CG-CZ2 3.42Å; F135-W218 VanDerWaalsContact CG-CZ2 3.42Å; F135-W218 AromaticContact CG-NE1 3.96Å; F135-W218 AromaticContact CZ-NE1 3.88Å; F135-I232 HydrophobicContact CD1-CG2 3.81Å; F135-M233 CarbonylContact C-O 3.59Å; F135-M233 VanDerWaalsContact CA-O 3.28Å; F135-M233 WeakPolarHBondContact CA-O 3.32Å; F135-F234 HydrophobicContact CD1-CB 3.88Å; F135-F234 HydrophobicContact CD1-CD2 4.18Å; F135-F234 HydrophobicContact CD1-CG 4.1Å; F135-F234 HydrophobicContact CD2-CD2 4.35Å; F135-F234 HydrophobicContact CE1-CB 3.57Å; F135-F234 AromaticContact CE1-CD1 3.92Å; F135-F234 HydrophobicContact CE1-CD1 3.92Å; F135-F234 AromaticContact CE1-CD2 3.81Å; F135-F234 HydrophobicContact CE1-CD2 3.81Å; F135-F234 HydrophobicContact CE1-CE2 4.49Å; F135-F234 AromaticContact CE1-CG 3.49Å; F135-F234 HydrophobicContact CE1-CG 3.49Å; F135-F234 VanDerWaalsContact CE1-CG 3.49Å; F135-F234 AromaticContact CE2-CD2 3.98Å; F135-F234 HydrophobicContact CE2-CD2 3.98Å; F135-F234 AromaticContact CE2-CE2 3.99Å; F135-F234 HydrophobicContact CE2-CE2 3.99Å; F135-F234 HydrophobicContact CE2-CG 4.42Å; F135-F234 HydrophobicContact CE2-CZ 4.4Å; F135-F234 HydrophobicContact CG-CD2 4.45Å; F135-F234 HydrophobicContact CZ-CB 4.28Å; F135-F234 AromaticContact CZ-CD1 3.85Å; F135-F234 HydrophobicContact CZ-CD1 3.85Å; F135-F234 AromaticContact CZ-CD2 3.69Å; F135-F234 HydrophobicContact CZ-CD2 3.69Å; F135-F234 HydrophobicContact CZ-CE1 4.05Å; F135-F234 AromaticContact CZ-CE2 3.92Å; F135-F234 HydrophobicContact CZ-CE2 3.92Å; F135-F234 AromaticContact CZ-CG 3.68Å; F135-F234 HydrophobicContact CZ-CG 3.68Å; F135-F234 HydrophobicContact CZ-CZ 4.09Å; F135-F353 HydrophobicContact CE1-CD2 4.32Å; F135-F353 HydrophobicContact CE1-CG 4.24Å
136T98.7Very high96.2Very high0 Ų038.7 Ų38.70%022%0.217CC..EExtended strand (participates in β ladder)trans-128.2134.6176.9-63.10000109Q148 Q149 I232 M233 W308 L311T136-Q148 HydrophobicContact CG2-CG 4.02Å; T136-Q149 WeakPolarHBondContact CA-O 3.47Å; T136-Q149 WeakPolarHBondContact CG2-O 3.32Å; T136-I232 CarbonylContact O-C 3.57Å; T136-I232 WeakPolarHBondContact O-CA 3.45Å; T136-M233 HydrophobicContact CG2-CE 4.32Å; T136-M233 PolarHBondContact N-O 2.95Å; T136-M233 PolarHBondContact O-N 2.79Å; T136-W308 HydrophobicContact CG2-CE3 4.4Å; T136-W308 HydrophobicContact CG2-CH2 3.98Å; T136-W308 HydrophobicContact CG2-CZ3 3.51Å; T136-L311 HydrophobicContact CG2-CD2 4.27Å
137V98.8Very high96.5Very high0 Ų039 Ų390%022%0.217CC..EExtended strand (participates in β ladder)trans-100.7141.4173.663.90000110.7L139 Y147 Q148 Q149 L151 L186 L193 V230 S231V137-L139 HydrophobicContact CG2-CD2 3.77Å; V137-L139 HydrophobicContact CG2-CG 4.37Å; V137-Y147 HydrophobicContact CG1-CD1 4.34Å; V137-Y147 HydrophobicContact CG1-CE1 4.06Å; V137-Q148 CarbonylContact O-C 3.57Å; V137-Q148 VanDerWaalsContact O-CA 3.24Å; V137-Q148 WeakPolarHBondContact O-CA 3.31Å; V137-Q148 WeakPolarHBondContact O-CG 3.38Å; V137-Q149 HydrophobicContact CG1-CB 4.19Å; V137-Q149 PolarHBondContact N-O 3.34Å; V137-Q149 PolarHBondContact O-N 3.32Å; V137-L151 HydrophobicContact CB-CD1 4.5Å; V137-L151 HydrophobicContact CG1-CD2 3.9Å; V137-L151 HydrophobicContact CG1-CG 4.4Å; V137-L186 HydrophobicContact CG1-CD1 4.14Å; V137-L186 HydrophobicContact CG1-CD2 4.43Å; V137-L186 HydrophobicContact CG2-CD1 4.47Å; V137-L193 HydrophobicContact CB-CD1 3.88Å; V137-L193 HydrophobicContact CG1-CD1 4.06Å; V137-L193 HydrophobicContact CG2-CD1 3.91Å; V137-V230 HydrophobicContact CG2-CG1 4.13Å; V137-S231 CarbonylContact C-O 3.55Å; V137-S231 WeakPolarHBondContact CA-O 3.2Å
138C98.7Very high96.7Very high0 Ų037.6 Ų37.60%021%0.212CC..EExtended strand (participates in β ladder)trans-126.1124.3167.7-178.50000108.9T145 Y147 Q148 V230 S231 L311C138-T145 VanDerWaalsContact SG-CG2 3.56Å; C138-Y147 CarbonylContact C-O 3.59Å; C138-Y147 WeakPolarHBondContact CA-O 3.43Å; C138-Q148 HydrophobicContact CB-CG 4.08Å; C138-Q148 PolarHBondContact SG-OE1 2.81Å; C138-V230 WeakPolarHBondContact O-CA 3.25Å; C138-S231 PolarHBondContact N-O 3.22Å; C138-S231 PolarHBondContact O-N 3.16Å; C138-L311 HydrophobicContact CB-CD2 4.12Å; C138-L311 HydrophobicContact CB-CG 4.12Å
139L98.6Very high97Very high0 Ų032.7 Ų32.70%019%0.191CC..EExtended strand (participates in β ladder)trans-107.7132.7174.6-50.6-178.6000109.3V137 V146 Y147 L186 Q189 V191 V230V137-L139 HydrophobicContact CG2-CD2 3.77Å; V137-L139 HydrophobicContact CG2-CG 4.37Å; L139-V146 HydrophobicContact CB-CG2 3.98Å; L139-V146 WeakPolarHBondContact O-CG2 3.44Å; L139-V146 PolarHBondContact O-N 2.9Å; L139-Y147 HydrophobicContact CD1-CD1 4.11Å; L139-Y147 HydrophobicContact CD1-CG 4.36Å; L139-Y147 HydrophobicContact CG-CD1 4.19Å; L139-Y147 PolarHBondContact N-O 2.74Å; L139-Y147 PolarHBondContact O-N 2.92Å; L139-L186 HydrophobicContact CD1-CD1 3.9Å; L139-L186 HydrophobicContact CD2-CD1 4.43Å; L139-L186 HydrophobicContact CG-CD1 4.41Å; L139-Q189 HydrophobicContact CD1-CB 3.82Å; L139-Q189 HydrophobicContact CD1-CG 3.95Å; L139-V191 HydrophobicContact CD1-CB 4.43Å; L139-V191 HydrophobicContact CD1-CG2 4.14Å; L139-V230 HydrophobicContact CD2-CB 4.28Å; L139-V230 HydrophobicContact CD2-CG1 3.85Å; L139-V230 HydrophobicContact CD2-CG2 3.68Å
140R98Very high97.1Very high23 Ų2330.9 Ų30.99%0.08718%0.18CC..EExtended strand (participates in β ladder)trans-128.5144.9-177.9-67.5172.46179-2.4111G143 Q144 T145 L228 D229 I312 T313 D314R140-G143 VanDerWaalsContact NH2-C 3.25Å; R140-G143 PolarHBondContact NH2-O 3.39Å; R140-Q144 CarbonylContact C-O 3.32Å; R140-Q144 VanDerWaalsContact CA-O 3.23Å; R140-Q144 WeakPolarHBondContact CA-O 3.28Å; R140-T145 WeakPolarHBondContact CG-OG1 3.43Å; R140-T145 PolarHBondContact NH1-OG1 2.75Å; R140-L228 WeakPolarHBondContact O-CD2 3.09Å; R140-D229 HydrophobicContact CB-CB 4.13Å; R140-D229 PolarHBondContact N-O 2.64Å; R140-D229 PolarHBondContact O-N 3.15Å; R140-I312 PolarHBondContact NH1-O 2.76Å; R140-T313 PolarHBondContact NH1-O 3.05Å; R140-T313 PolarHBondContact NH2-O 2.79Å; R140-D314 VanDerWaalsContact NE-C 3.34Å; R140-D314 PolarHBondContact NE-O 2.84Å
141R96.3Very high97.2Very high124 Ų12430.5 Ų30.547%0.46818%0.178SC..EExtended strand (participates in β ladder)trans-140.8125.2176.7-173.7179.467.5-177-0.8109.2G143 Q144 V146 Y226 L228R141-G143 VanDerWaalsContact C-N 3.27Å; R141-G143 PolarHBondContact O-N 2.78Å; R141-Q144 PolarHBondContact N-O 2.8Å; R141-Q144 PolarHBondContact O-N 2.75Å; R141-V146 HydrophobicContact CB-CG1 4.06Å; R141-Y226 HydrophobicContact CG-CD2 4.46Å; R141-L228 HydrophobicContact CB-CD2 4.24Å
142G93Very high97.3Very high80 Ų8028.5 Ų28.583%0.82517%0.168SC*.THydrogen-bonded Turntrans59.436.9179.600000113.2Q144G142-Q144 VanDerWaalsContact C-N 3.27Å; G142-Q144 PolarHBondContact O-N 2.98Å
143G91.9Very high97.3Very high46 Ų4629.4 Ų29.447%0.47417%0.172SC..THydrogen-bonded Turntrans74.310.2-178.900000115.3R140 R141R140-G143 VanDerWaalsContact NH2-C 3.25Å; R140-G143 PolarHBondContact NH2-O 3.39Å; R141-G143 VanDerWaalsContact C-N 3.27Å; R141-G143 PolarHBondContact O-N 2.78Å
144Q96.3Very high97.2Very high148 Ų14832.7 Ų32.769%0.69219%0.188SC*.EExtended strand (participates in β ladder)trans-120.2136.9176.5-65-173.9-17.200111.2R140 R141 G142 V146R140-Q144 CarbonylContact C-O 3.32Å; R140-Q144 VanDerWaalsContact CA-O 3.23Å; R140-Q144 WeakPolarHBondContact CA-O 3.28Å; R141-Q144 PolarHBondContact N-O 2.8Å; R141-Q144 PolarHBondContact O-N 2.75Å; G142-Q144 VanDerWaalsContact C-N 3.27Å; G142-Q144 PolarHBondContact O-N 2.98Å; Q144-V146 PolarHBondContact O-N 3Å
145T97.8Very high97Very high38 Ų3842.3 Ų42.323%0.23322%0.224CC..EExtended strand (participates in β ladder)trans-70.4122.3172.5-62.80000110.3C138 R140 Q148 I312C138-T145 VanDerWaalsContact SG-CG2 3.56Å; R140-T145 WeakPolarHBondContact CG-OG1 3.43Å; R140-T145 PolarHBondContact NH1-OG1 2.75Å; T145-Q148 HydrophobicContact CG2-CB 4.36Å; T145-I312 WeakPolarHBondContact CB-O 3.49Å; T145-I312 HydrophobicContact CG2-CG1 4.49Å; T145-I312 PolarHBondContact OG1-O 2.87Å
146V97.3Very high96.8Very high63 Ų6342.7 Ų42.738%0.38223%0.227SC..EExtended strand (participates in β ladder)trans-103.4-21.4178.9-62.80000112.3L139 R141 Q144L139-V146 HydrophobicContact CB-CG2 3.98Å; L139-V146 WeakPolarHBondContact O-CG2 3.44Å; L139-V146 PolarHBondContact O-N 2.9Å; R141-V146 HydrophobicContact CB-CG1 4.06Å; Q144-V146 PolarHBondContact O-N 3Å
147Y98.1Very high96.3Very high38 Ų3848.5 Ų48.515%0.14926%0.264CS..EExtended strand (participates in β ladder)trans-156.9133.7-179.3-174.7-97.6000110.9V137 C138 L139 Q149 L186 Q189V137-Y147 HydrophobicContact CG1-CD1 4.34Å; V137-Y147 HydrophobicContact CG1-CE1 4.06Å; C138-Y147 CarbonylContact C-O 3.59Å; C138-Y147 WeakPolarHBondContact CA-O 3.43Å; L139-Y147 HydrophobicContact CD1-CD1 4.11Å; L139-Y147 HydrophobicContact CD1-CG 4.36Å; L139-Y147 HydrophobicContact CG-CD1 4.19Å; L139-Y147 PolarHBondContact N-O 2.74Å; L139-Y147 PolarHBondContact O-N 2.92Å; Y147-Q149 HydrophobicContact CD1-CB 4.29Å; Y147-Q149 HydrophobicContact CE1-CB 3.41Å; Y147-Q149 VanDerWaalsContact CE1-CB 3.41Å; Y147-Q149 HydrophobicContact CE1-CG 4.23Å; Y147-Q149 WeakPolarHBondContact OH-CB 3.36Å; Y147-Q149 WeakPolarHBondContact OH-CG 3.45Å; Y147-L186 HydrophobicContact CD1-CD1 4.25Å; Y147-L186 HydrophobicContact CE1-CB 4.47Å; Y147-L186 HydrophobicContact CE1-CD1 3.99Å; Y147-L186 HydrophobicContact CE1-CD2 4.09Å; Y147-L186 HydrophobicContact CE1-CG 4.42Å; Y147-Q189 HydrophobicContact CD1-CG 4.28Å; Y147-Q189 HydrophobicContact CD2-CG 3.8Å; Y147-Q189 HydrophobicContact CE2-CG 4.21Å; Y147-Q189 HydrophobicContact CG-CG 3.84Å
148Q98.3Very high95.9Very high14 Ų1451.2 Ų51.27%0.06528%0.281CS..EExtended strand (participates in β ladder)trans-142.1132.5169.4-167.6172.4-70.500110.5T136 V137 C138 T145 N163 W308 I312T136-Q148 HydrophobicContact CG2-CG 4.02Å; V137-Q148 CarbonylContact O-C 3.57Å; V137-Q148 VanDerWaalsContact O-CA 3.24Å; V137-Q148 WeakPolarHBondContact O-CA 3.31Å; V137-Q148 WeakPolarHBondContact O-CG 3.38Å; C138-Q148 HydrophobicContact CB-CG 4.08Å; C138-Q148 PolarHBondContact SG-OE1 2.81Å; T145-Q148 HydrophobicContact CG2-CB 4.36Å; Q148-N163 PolarHBondContact O-ND2 3.49Å; Q148-W308 HydrophobicContact CB-CH2 4.28Å; Q148-W308 HydrophobicContact CB-CZ2 3.94Å; Q148-W308 HydrophobicContact CG-CH2 3.62Å; Q148-W308 HydrophobicContact CG-CZ2 3.65Å; Q148-W308 HydrophobicContact CG-CZ3 4.18Å; Q148-W308 VanDerWaalsContact NE2-CE3 3.31Å; Q148-W308 PolarHBondContact NE2-O 2.84Å; Q148-W308 VanDerWaalsContact NE2-O 3.16Å; Q148-I312 HydrophobicContact CB-CG1 4.42Å; Q148-I312 VanDerWaalsContact OE1-CG1 3.24Å
149Q98Very high95.7Very high14 Ų1451.2 Ų51.27%0.06528%0.281CS..EExtended strand (participates in β ladder)trans-152.4131.6-169.4178.766.158.500111.6T136 V137 Y147 N163 Y166T136-Q149 WeakPolarHBondContact CA-O 3.47Å; T136-Q149 WeakPolarHBondContact CG2-O 3.32Å; V137-Q149 HydrophobicContact CG1-CB 4.19Å; V137-Q149 PolarHBondContact N-O 3.34Å; V137-Q149 PolarHBondContact O-N 3.32Å; Y147-Q149 HydrophobicContact CD1-CB 4.29Å; Y147-Q149 HydrophobicContact CE1-CB 3.41Å; Y147-Q149 VanDerWaalsContact CE1-CB 3.41Å; Y147-Q149 HydrophobicContact CE1-CG 4.23Å; Y147-Q149 WeakPolarHBondContact OH-CB 3.36Å; Y147-Q149 WeakPolarHBondContact OH-CG 3.45Å; Q149-N163 PolarHBondContact NE2-O 3.34Å; Q149-N163 PolarHBondContact OE1-ND2 3.16Å; Q149-Y166 HydrophobicContact CG-CD2 3.84Å
150V98.4Very high95.5Very high0 Ų056.5 Ų56.50%031%0.305CS..EExtended strand (participates in β ladder)trans-72.1128.3165.7-1730000108.1Q134 S152 W162 N163 W164 W308Q134-V150 HydrophobicContact CB-CG1 4.14Å; Q134-V150 HydrophobicContact CG-CG1 4.02Å; V150-S152 PolarHBondContact O-N 2.97Å; V150-W162 HydrophobicContact CG2-CB 3.77Å; V150-W162 HydrophobicContact CG2-CD2 4.39Å; V150-W162 HydrophobicContact CG2-CE3 3.75Å; V150-W162 HydrophobicContact CG2-CG 4.47Å; V150-N163 WeakPolarHBondContact CB-O 3.45Å; V150-N163 WeakPolarHBondContact CG2-O 3.04Å; V150-N163 PolarHBondContact N-O 2.86Å; V150-W164 HydrophobicContact CB-CD2 4.23Å; V150-W164 HydrophobicContact CB-CE3 4.07Å; V150-W164 HydrophobicContact CB-CZ3 4.37Å; V150-W164 HydrophobicContact CG1-CD2 4.21Å; V150-W164 HydrophobicContact CG1-CE3 3.7Å; V150-W164 HydrophobicContact CG1-CH2 3.82Å; V150-W164 HydrophobicContact CG1-CZ2 4.27Å; V150-W164 HydrophobicContact CG1-CZ3 3.5Å; V150-W164 HydrophobicContact CG2-CD2 4.16Å; V150-W164 HydrophobicContact CG2-CE3 4.46Å; V150-W164 HydrophobicContact CG2-CZ2 4.44Å; V150-W308 HydrophobicContact CG2-CH2 4.05Å; V150-W308 HydrophobicContact CG2-CZ3 3.62Å
151L98.1Very high95.3Very high1 Ų156.4 Ų56.41%0.00531%0.312CS..SBendtrans-82.153.2-175.8-62.2177.5000111.8F135 V137 Y184 L186 L193 W218F135-L151 HydrophobicContact CB-CD1 4.35Å; F135-L151 WeakPolarHBondContact O-CB 3.39Å; F135-L151 PolarHBondContact O-N 2.95Å; V137-L151 HydrophobicContact CB-CD1 4.5Å; V137-L151 HydrophobicContact CG1-CD2 3.9Å; V137-L151 HydrophobicContact CG1-CG 4.4Å; L151-Y184 HydrophobicContact CB-CD1 4.41Å; L151-Y184 HydrophobicContact CB-CE1 3.85Å; L151-Y184 HydrophobicContact CB-CE2 4.24Å; L151-Y184 HydrophobicContact CD1-CD2 4.43Å; L151-Y184 HydrophobicContact CD1-CE2 4.34Å; L151-Y184 HydrophobicContact CD2-CD1 4.05Å; L151-Y184 HydrophobicContact CD2-CE1 4.35Å; L151-Y184 HydrophobicContact CD2-CG 4.15Å; L151-Y184 PolarHBondContact O-OH 3.01Å; L151-L186 HydrophobicContact CD2-CD2 4.35Å; L151-L193 HydrophobicContact CD1-CD1 3.95Å; L151-L193 HydrophobicContact CD2-CD1 4.19Å; L151-W218 HydrophobicContact CD1-CH2 3.24Å; L151-W218 HydrophobicContact CD1-CZ2 4.17Å; L151-W218 HydrophobicContact CD1-CZ3 3.48Å; L151-W218 VanDerWaalsContact CD1-CZ3 3.48Å
152S96.8Very high95.4Very high0 Ų051 Ų510%029%0.291CS..  trans-141141.5-178-177.40000111.1V150 E154 G165 Y166V150-S152 PolarHBondContact O-N 2.97Å; S152-E154 WeakPolarHBondContact OG-CB 3.3Å; S152-E154 PolarHBondContact OG-N 2.99Å; S152-G165 PolarHBondContact O-N 3.49Å; S152-Y166 WeakPolarHBondContact O-CB 3Å; S152-Y166 PolarHBondContact O-N 2.99Å
153V96.1Very high95.6Very high27 Ų2750.7 Ų50.716%0.16427%0.271CS..SBendtrans-77.4-12.4174.5-55.90000112.7L35 R112 Y166L35-V153 HydrophobicContact CB-CG1 4.22Å; L35-V153 HydrophobicContact CD2-CG1 4.29Å; R112-V153 HydrophobicContact CB-CG2 4.17Å; R112-V153 HydrophobicContact CG-CG2 4.14Å; V153-Y166 WeakPolarHBondContact CG1-O 3.3Å
154E94.8Very high95.8Very high69 Ų6949.6 Ų49.632%0.32225%0.252SS..  trans-70156.1-176.9-70.4-61.8135.300112.4E114 S152 W164 G165E114-E154 HydrophobicContact CG-CG 4.32Å; S152-E154 WeakPolarHBondContact OG-CB 3.3Å; S152-E154 PolarHBondContact OG-N 2.99Å; E154-W164 WeakPolarHBondContact O-CB 3.24Å; E154-G165 PolarHBondContact O-N 2.96Å
155R94.8Very high95.8Very high202 Ų20243.2 Ų43.276%0.76223%0.227SC*.  trans-131.379.3171.1-65.8-176.1-176.9-166.6-1.7108.7
156P93.7Very high95.8Very high10 Ų1041.9 Ų41.97%0.06522%0.217CC..  trans-67.4168.5-174.728.6-34.9000111.7I131 T158 Q160 W164I131-P156 HydrophobicContact CG1-CB 4.44Å; I131-P156 HydrophobicContact CG2-CB 3.4Å; I131-P156 HydrophobicContact CG2-CG 3.6Å; P156-T158 WeakPolarHBondContact CG-O 3.48Å; P156-Q160 PolarHBondContact O-NE2 3.48Å; P156-W164 VanDerWaalsContact CD-CD2 3.47Å; P156-W164 HydrophobicContact CG-CD2 3.77Å; P156-W164 HydrophobicContact CG-CE3 4.12Å; P156-W164 HydrophobicContact CG-CG 4.26Å; P156-W164 HydrophobicContact CG-CH2 4.08Å; P156-W164 HydrophobicContact CG-CZ2 3.77Å; P156-W164 HydrophobicContact CG-CZ3 4.25Å
157P89.3Confident95.8Very high121 Ų12141.8 Ų41.879%0.78622%0.219SC*.SBendtrans-86.5-12.617232.8-35000113.7
158T89.5Confident95.7Very high57 Ų5740.3 Ų40.335%0.3522%0.215SC..SBendtrans-104.5172.4172.453.10000109.9P156 Q160P156-T158 WeakPolarHBondContact CG-O 3.48Å; T158-Q160 PolarHBondContact O-N 2.83Å; T158-Q160 PolarHBondContact O-NE2 2.92Å
159L93.9Very high95.6Very high1 Ų143 Ų431%0.00523%0.228CC..  trans58.930.6178.6-50.1173.4000113.1I131 A132 G161 W162 W164 G302 T303 C304I131-L159 HydrophobicContact CG2-CD1 4.25Å; A132-L159 HydrophobicContact CB-CD1 3.83Å; L159-G161 PolarHBondContact O-N 3Å; L159-G161 VanDerWaalsContact O-N 3.13Å; L159-W162 HydrophobicContact CB-CD2 4.12Å; L159-W162 HydrophobicContact CB-CE3 4.35Å; L159-W162 HydrophobicContact CB-CG 4.38Å; L159-W162 HydrophobicContact CD1-CE3 4.3Å; L159-W162 HydrophobicContact CD1-CH2 4.11Å; L159-W162 HydrophobicContact CD1-CZ3 4Å; L159-W162 HydrophobicContact CD2-CH2 4.38Å; L159-W162 HydrophobicContact CD2-CZ2 4.03Å; L159-W162 WeakPolarHBondContact O-CB 3.42Å; L159-W162 PolarHBondContact O-N 3.42Å; L159-W164 HydrophobicContact CB-CZ2 3.94Å; L159-W164 HydrophobicContact CD1-CH2 4.44Å; L159-W164 HydrophobicContact CD1-CZ2 3.77Å; L159-W164 HydrophobicContact CG-CZ2 4.49Å; L159-W164 PolarHBondContact O-NE1 2.82Å; L159-G302 PolarHBondContact N-O 2.98Å; L159-T303 CarbonylContact C-O 3.44Å; L159-T303 VanDerWaalsContact C-O 3.32Å; L159-T303 WeakPolarHBondContact CA-O 3.22Å; L159-C304 HydrophobicContact CD2-CB 3.62Å; L159-C304 WeakPolarHBondContact CD2-SG 3.38Å
160Q94.5Very high95.6Very high110 Ų11046.2 Ų46.251%0.51424%0.24SC..THydrogen-bonded Turntrans-66.2-11.6-176.1-63.1-56.1-83.900114.5P156 T158 W162 T303P156-Q160 PolarHBondContact O-NE2 3.48Å; T158-Q160 PolarHBondContact O-N 2.83Å; T158-Q160 PolarHBondContact O-NE2 2.92Å; Q160-W162 PolarHBondContact O-N 3.13Å; Q160-T303 HydrophobicContact CB-CG2 4.46Å
161G95.5Very high95.6Very high21 Ų2146.2 Ų46.222%0.21624%0.24CC..THydrogen-bonded Turntrans-73.2-11.6172.100000113L159 T303 W308L159-G161 PolarHBondContact O-N 3Å; L159-G161 VanDerWaalsContact O-N 3.13Å; G161-T303 WeakPolarHBondContact CA-O 3.46Å; G161-T303 PolarHBondContact N-O 3.42Å; G161-W308 VanDerWaalsContact O-CD1 3.22Å
162W97.3Very high95.6Very high11 Ų1146.2 Ų46.24%0.04224%0.24CC..SBendtrans-96.5153-177.2-55.15.1000111V150 L159 Q160 W164 T235 F298 C304 L307 W308V150-W162 HydrophobicContact CG2-CB 3.77Å; V150-W162 HydrophobicContact CG2-CD2 4.39Å; V150-W162 HydrophobicContact CG2-CE3 3.75Å; V150-W162 HydrophobicContact CG2-CG 4.47Å; L159-W162 HydrophobicContact CB-CD2 4.12Å; L159-W162 HydrophobicContact CB-CE3 4.35Å; L159-W162 HydrophobicContact CB-CG 4.38Å; L159-W162 HydrophobicContact CD1-CE3 4.3Å; L159-W162 HydrophobicContact CD1-CH2 4.11Å; L159-W162 HydrophobicContact CD1-CZ3 4Å; L159-W162 HydrophobicContact CD2-CH2 4.38Å; L159-W162 HydrophobicContact CD2-CZ2 4.03Å; L159-W162 WeakPolarHBondContact O-CB 3.42Å; L159-W162 PolarHBondContact O-N 3.42Å; Q160-W162 PolarHBondContact O-N 3.13Å; W162-W164 HydrophobicContact CD2-CZ2 4.47Å; W162-W164 HydrophobicContact CE3-CH2 4.42Å; W162-W164 AromaticContact CE3-CZ2 3.61Å; W162-W164 HydrophobicContact CE3-CZ2 3.61Å; W162-W164 HydrophobicContact CZ3-CZ2 4.09Å; W162-W164 VanDerWaalsContact O-CD1 3.24Å; W162-W164 PolarHBondContact O-N 3.39Å; W162-T235 HydrophobicContact CH2-CG2 3.97Å; W162-F298 HydrophobicContact CZ2-CE2 4.47Å; W162-C304 HydrophobicContact CZ2-CB 4.35Å; W162-C304 PolarHBondContact NE1-O 2.93Å; W162-C304 VanDerWaalsContact NE1-O 3.08Å; W162-L307 HydrophobicContact CZ2-CD2 4.02Å; W162-W308 HydrophobicContact CB-CD2 3.93Å; W162-W308 HydrophobicContact CB-CE3 3.44Å; W162-W308 VanDerWaalsContact CB-CE3 3.44Å; W162-W308 HydrophobicContact CB-CH2 4.31Å; W162-W308 HydrophobicContact CB-CZ3 3.64Å; W162-W308 AromaticContact CD1-CD2 3.95Å; W162-W308 AromaticContact CD1-CE3 3.67Å; W162-W308 AromaticContact CD1-CG 3.94Å; W162-W308 HydrophobicContact CD2-CE3 4.02Å; W162-W308 HydrophobicContact CD2-CZ3 4.46Å; W162-W308 HydrophobicContact CG-CB 4.45Å; W162-W308 HydrophobicContact CG-CD2 4.03Å; W162-W308 AromaticContact CG-CE3 3.42Å; W162-W308 HydrophobicContact CG-CE3 3.42Å; W162-W308 VanDerWaalsContact CG-CE3 3.42Å; W162-W308 HydrophobicContact CG-CG 4.48Å; W162-W308 HydrophobicContact CG-CZ3 4Å
163N97.3Very high95.7Very high73 Ų7346.2 Ų46.239%0.3924%0.24SC..  trans-83.699.5175.5-17528.5000110.6Q148 Q149 V150 W308Q148-N163 PolarHBondContact O-ND2 3.49Å; Q149-N163 PolarHBondContact NE2-O 3.34Å; Q149-N163 PolarHBondContact OE1-ND2 3.16Å; V150-N163 WeakPolarHBondContact CB-O 3.45Å; V150-N163 WeakPolarHBondContact CG2-O 3.04Å; V150-N163 PolarHBondContact N-O 2.86Å; N163-W308 HydrophobicContact CB-CH2 3.71Å; N163-W308 HydrophobicContact CB-CZ2 3.41Å; N163-W308 VanDerWaalsContact CB-CZ2 3.41Å; N163-W308 VanDerWaalsContact N-CH2 3.29Å
164W97.3Very high95.8Very high23 Ų2344.9 Ų44.99%0.08723%0.232CC..  trans-99177.1-177-74.5100.8000113.2I131 Q134 V150 E154 P156 L159 W162I131-W164 HydrophobicContact CG2-CH2 4.08Å; I131-W164 HydrophobicContact CG2-CZ2 4.42Å; Q134-W164 HydrophobicContact CG-CH2 3.58Å; Q134-W164 HydrophobicContact CG-CZ3 4.09Å; V150-W164 HydrophobicContact CB-CD2 4.23Å; V150-W164 HydrophobicContact CB-CE3 4.07Å; V150-W164 HydrophobicContact CB-CZ3 4.37Å; V150-W164 HydrophobicContact CG1-CD2 4.21Å; V150-W164 HydrophobicContact CG1-CE3 3.7Å; V150-W164 HydrophobicContact CG1-CH2 3.82Å; V150-W164 HydrophobicContact CG1-CZ2 4.27Å; V150-W164 HydrophobicContact CG1-CZ3 3.5Å; V150-W164 HydrophobicContact CG2-CD2 4.16Å; V150-W164 HydrophobicContact CG2-CE3 4.46Å; V150-W164 HydrophobicContact CG2-CZ2 4.44Å; E154-W164 WeakPolarHBondContact O-CB 3.24Å; P156-W164 VanDerWaalsContact CD-CD2 3.47Å; P156-W164 HydrophobicContact CG-CD2 3.77Å; P156-W164 HydrophobicContact CG-CE3 4.12Å; P156-W164 HydrophobicContact CG-CG 4.26Å; P156-W164 HydrophobicContact CG-CH2 4.08Å; P156-W164 HydrophobicContact CG-CZ2 3.77Å; P156-W164 HydrophobicContact CG-CZ3 4.25Å; L159-W164 HydrophobicContact CB-CZ2 3.94Å; L159-W164 HydrophobicContact CD1-CH2 4.44Å; L159-W164 HydrophobicContact CD1-CZ2 3.77Å; L159-W164 HydrophobicContact CG-CZ2 4.49Å; L159-W164 PolarHBondContact O-NE1 2.82Å; W162-W164 HydrophobicContact CD2-CZ2 4.47Å; W162-W164 HydrophobicContact CE3-CH2 4.42Å; W162-W164 AromaticContact CE3-CZ2 3.61Å; W162-W164 HydrophobicContact CE3-CZ2 3.61Å; W162-W164 HydrophobicContact CZ3-CZ2 4.09Å; W162-W164 VanDerWaalsContact O-CD1 3.24Å; W162-W164 PolarHBondContact O-N 3.39Å
165G95.6Very high96Very high15 Ų1541.6 Ų41.616%0.15522%0.217CC..  trans74.543.2170.400000113.8S152 E154 C167S152-G165 PolarHBondContact O-N 3.49Å; E154-G165 PolarHBondContact O-N 2.96Å; G165-C167 PolarHBondContact O-N 3.19Å
166Y97.4Very high96.1Very high9 Ų932 Ų324%0.03518%0.18CC..  trans-51.1138.1171.1-177.6-91.3000110.3Q149 S152 V153 G168 Y170 A171 Y184 Q185 L186Q149-Y166 HydrophobicContact CG-CD2 3.84Å; S152-Y166 WeakPolarHBondContact O-CB 3Å; S152-Y166 PolarHBondContact O-N 2.99Å; V153-Y166 WeakPolarHBondContact CG1-O 3.3Å; Y166-G168 PolarHBondContact O-N 3.13Å; Y166-G168 VanDerWaalsContact O-N 3.11Å; Y166-Y170 PolarHBondContact OH-O 3.25Å; Y166-A171 HydrophobicContact CD1-CB 4.43Å; Y166-A171 HydrophobicContact CE1-CB 3.68Å; Y166-Y184 HydrophobicContact CD1-CD1 4.02Å; Y166-Y184 HydrophobicContact CD1-CE1 4.37Å; Y166-Y184 AromaticContact CE1-CD1 3.69Å; Y166-Y184 HydrophobicContact CE1-CD1 3.69Å; Y166-Y184 HydrophobicContact CE1-CE1 4.44Å; Y166-Y184 HydrophobicContact CE2-CD1 4.39Å; Y166-Y184 AromaticContact CZ-CD1 3.86Å; Y166-Q185 PolarHBondContact OH-N 2.95Å; Y166-Q185 PolarHBondContact OH-O 3.21Å; Y166-L186 HydrophobicContact CE2-CD2 3.95Å
167C96.6Very high96.4Very high62 Ų6231.6 Ų31.642%0.41918%0.178SC..  trans-74.2106.3-178.9-175.80000110.5G165 E169 Y170G165-C167 PolarHBondContact O-N 3.19Å; C167-E169 PolarHBondContact O-N 2.8Å; C167-Y170 HydrophobicContact CB-CD2 3.97Å; C167-Y170 PolarHBondContact O-N 3.13Å
168G96.8Very high96.8Very high7 Ų726 Ų267%0.07214%0.141CC..G310 helixtrans-61.3-13.4-177.600000115.5C34 L35 A36 Y166 Y170 A171C34-G168 PolarHBondContact SG-O 3.45Å; C34-G168 VanDerWaalsContact SG-O 3.35Å; L35-G168 WeakPolarHBondContact CB-O 3.43Å; L35-G168 PolarHBondContact N-O 2.98Å; A36-G168 PolarHBondContact N-O 2.97Å; Y166-G168 PolarHBondContact O-N 3.13Å; Y166-G168 VanDerWaalsContact O-N 3.11Å; G168-Y170 PolarHBondContact O-N 3.43Å; G168-A171 PolarHBondContact O-N 2.61Å
169E97.1Very high97.2Very high71 Ų7123.7 Ų23.733%0.33213%0.126SC..G310 helixtrans-70.8-19.8174.9-63.1-173.317500112.2R16 Y17 A18 A36 C167R16-E169 IonicContact CZ-OE1 2.76Å; R16-E169 IonicContact NE-OE1 3.37Å; R16-E169 IonicContact NH2-OE1 3.03Å; R16-E169 PolarHBondContact NH2-OE1 3.05Å; R16-E169 WeakPolarHBondContact O-CB 3.31Å; Y17-E169 CarbonylContact C-O 3.58Å; Y17-E169 WeakPolarHBondContact CA-O 3.45Å; Y17-E169 VanDerWaalsContact CD2-O 3.28Å; Y17-E169 WeakPolarHBondContact CD2-O 3.41Å; A18-E169 PolarHBondContact N-O 3.1Å; A36-E169 HydrophobicContact CB-CG 3.63Å; C167-E169 PolarHBondContact O-N 2.8Å
170Y97.1Very high97.5Very high81 Ų8123.7 Ų23.732%0.31813%0.126SC..G310 helixtrans-100.520.8175.1-63-87.3000112.6A18 Y166 C167 G168 Q185 P187A18-Y170 HydrophobicContact CB-CD1 4.09Å; A18-Y170 HydrophobicContact CB-CE1 3.86Å; Y166-Y170 PolarHBondContact OH-O 3.25Å; C167-Y170 HydrophobicContact CB-CD2 3.97Å; C167-Y170 PolarHBondContact O-N 3.13Å; G168-Y170 PolarHBondContact O-N 3.43Å; Y170-Q185 PolarHBondContact O-N 3.17Å; Y170-P187 HydrophobicContact CD1-CG 3.9Å; Y170-P187 HydrophobicContact CD2-CG 3.77Å; Y170-P187 HydrophobicContact CE1-CG 4.25Å; Y170-P187 HydrophobicContact CE2-CG 4.14Å; Y170-P187 HydrophobicContact CG-CG 3.63Å
171A97.9Very high97.7Very high0 Ų018.5 Ų18.50%010%0.102CC..EExtended strand (participates in β ladder)trans-144.9152.2173.100000112.5L35 Y166 G168 V183 Y184L35-A171 HydrophobicContact CB-CB 4.09Å; L35-A171 HydrophobicContact CD1-CB 4.09Å; L35-A171 HydrophobicContact CD2-CB 3.79Å; L35-A171 HydrophobicContact CG-CB 4.19Å; L35-A171 PolarHBondContact N-O 3.35Å; Y166-A171 HydrophobicContact CD1-CB 4.43Å; Y166-A171 HydrophobicContact CE1-CB 3.68Å; G168-A171 PolarHBondContact O-N 2.61Å; A171-V183 CarbonylContact C-O 3.35Å; A171-V183 WeakPolarHBondContact CA-O 3.49Å; A171-V183 WeakPolarHBondContact CB-O 3.37Å; A171-Y184 HydrophobicContact CB-CD1 3.76Å; A171-Y184 HydrophobicContact CB-CE1 4.22Å; A171-Y184 HydrophobicContact CB-CG 4.32Å
172F98.1Very high97.8Very high0 Ų017.6 Ų17.60%09%0.092CC..EExtended strand (participates in β ladder)trans-138.4157.7168.171.8-94.6000111.4M14 Y17 E21 M22 V26 R32 I33 L35 H174 T182 V183M14-F172 HydrophobicContact CE-CB 3.67Å; M14-F172 HydrophobicContact CE-CD1 3.83Å; M14-F172 HydrophobicContact CE-CD2 4.42Å; M14-F172 HydrophobicContact CE-CG 3.72Å; M14-F172 HydrophobicContact SD-CB 3.88Å; M14-F172 HydrophobicContact SD-CG 4.36Å; Y17-F172 HydrophobicContact CD1-CD1 4.1Å; Y17-F172 HydrophobicContact CD2-CB 4.39Å; Y17-F172 HydrophobicContact CD2-CD1 4.18Å; Y17-F172 AromaticContact CE1-CD1 3.56Å; Y17-F172 HydrophobicContact CE1-CD1 3.56Å; Y17-F172 AromaticContact CE1-CE1 3.8Å; Y17-F172 HydrophobicContact CE1-CE1 3.8Å; Y17-F172 AromaticContact CE2-CD1 3.69Å; Y17-F172 HydrophobicContact CE2-CD1 3.69Å; Y17-F172 HydrophobicContact CE2-CE1 4.48Å; Y17-F172 HydrophobicContact CG-CD1 4.37Å; Y17-F172 AromaticContact CZ-CD1 3.33Å; Y17-F172 AromaticContact CZ-CE1 3.71Å; E21-F172 WeakPolarHBondContact O-CE1 3.5Å; M22-F172 WeakPolarHBondContact O-CZ 3.34Å; V26-F172 HydrophobicContact CG1-CE2 4.27Å; R32-F172 HydrophobicContact CG-CD2 3.6Å; R32-F172 HydrophobicContact CG-CE2 4.07Å; R32-F172 HydrophobicContact CG-CG 4.31Å; I33-F172 CarbonylContact O-C 3.6Å; I33-F172 VanDerWaalsContact O-CA 3.3Å; I33-F172 WeakPolarHBondContact O-CA 3.43Å; I33-F172 WeakPolarHBondContact O-CB 3.47Å; L35-F172 VanDerWaalsContact CD1-CA 3.45Å; F172-H174 HydrophobicContact CD2-CB 4.29Å; F172-H174 HydrophobicContact CE2-CB 4.07Å; F172-T182 WeakPolarHBondContact O-CA 3.35Å; F172-V183 HydrophobicContact CD1-CB 4.04Å; F172-V183 HydrophobicContact CE1-CB 3.63Å; F172-V183 HydrophobicContact CE1-CG1 3.92Å; F172-V183 HydrophobicContact CE1-CG2 3.89Å; F172-V183 HydrophobicContact CE2-CB 4.26Å; F172-V183 HydrophobicContact CE2-CG2 3.85Å; F172-V183 HydrophobicContact CZ-CB 3.76Å; F172-V183 HydrophobicContact CZ-CG1 4.32Å; F172-V183 HydrophobicContact CZ-CG2 3.46Å; F172-V183 VanDerWaalsContact CZ-CG2 3.46Å; F172-V183 PolarHBondContact N-O 2.78Å; F172-V183 VanDerWaalsContact N-O 3.1Å; F172-V183 PolarHBondContact O-N 3.34Å
173Y98.6Very high97.9Very high0 Ų017 Ų170%09%0.09CC..EExtended strand (participates in β ladder)trans-106.9143.9171.7178.8-100.1000109.6W31 R32 I33 A97 W111 A175 A180 W181 F809W31-Y173 HydrophobicContact CE3-CD1 4.14Å; W31-Y173 HydrophobicContact CE3-CE1 4.03Å; W31-Y173 AromaticContact CZ3-CD1 3.93Å; W31-Y173 HydrophobicContact CZ3-CD1 3.93Å; W31-Y173 AromaticContact CZ3-CE1 3.87Å; W31-Y173 HydrophobicContact CZ3-CE1 3.87Å; R32-Y173 WeakPolarHBondContact CA-O 3.41Å; R32-Y173 WeakPolarHBondContact CG-O 3.23Å; I33-Y173 HydrophobicContact CG2-CD1 4.12Å; I33-Y173 PolarHBondContact N-O 3.39Å; I33-Y173 PolarHBondContact O-N 2.88Å; A97-Y173 WeakPolarHBondContact CB-OH 3.27Å; A97-Y173 PolarHBondContact N-OH 3.31Å; W111-Y173 HydrophobicContact CB-CD1 3.42Å; W111-Y173 VanDerWaalsContact CB-CD1 3.42Å; W111-Y173 HydrophobicContact CB-CD2 4.17Å; W111-Y173 HydrophobicContact CB-CE1 3.87Å; W111-Y173 HydrophobicContact CB-CG 3.58Å; W111-Y173 VanDerWaalsContact O-CB 3.28Å; W111-Y173 WeakPolarHBondContact O-CB 3.39Å; Y173-A175 HydrophobicContact CE1-CB 3.6Å; Y173-A180 HydrophobicContact CE2-CB 3.72Å; Y173-A180 WeakPolarHBondContact OH-CB 3.03Å; Y173-W181 CarbonylContact C-O 3.6Å; Y173-W181 WeakPolarHBondContact CA-O 3.32Å; Y173-W181 WeakPolarHBondContact CD2-O 3.5Å; Y173-F809 HydrophobicContact CE1-CE2 4.48Å
174H98.4Very high97.9Very high0 Ų013.6 Ų13.60%07%0.071CC..EExtended strand (participates in β ladder)trans-136.9130.5176.2-171.776.5000109.8V26 P27 E29 W31 R32 F172 A180 W181V26-H174 HydrophobicContact CG1-CB 4Å; P27-H174 PolarHBondContact O-NE2 2.76Å; E29-H174 PolarHBondContact O-CE1 3.16Å; E29-H174 PolarHBondContact O-NE2 2.94Å; W31-H174 CarbonylContact O-C 3.6Å; W31-H174 VanDerWaalsContact O-CA 3.24Å; W31-H174 WeakPolarHBondContact O-CA 3.45Å; R32-H174 HydrophobicContact CG-CB 4.34Å; R32-H174 PolarHBondContact NE-ND1 2.72Å; F172-H174 HydrophobicContact CD2-CB 4.29Å; F172-H174 HydrophobicContact CE2-CB 4.07Å; H174-A180 CarbonylContact O-C 3.6Å; H174-A180 VanDerWaalsContact O-CA 3.24Å; H174-A180 WeakPolarHBondContact O-CA 3.24Å; H174-A180 WeakPolarHBondContact O-CB 3.25Å; H174-W181 HydrophobicContact CB-CB 4.33Å; H174-W181 AromaticContact CD2-CE3 3.72Å; H174-W181 PolarHBondContact N-O 2.8Å; H174-W181 PolarHBondContact O-N 3.28Å
175A98.5Very high97.9Very high0 Ų014.7 Ų14.70%08%0.077CC..EExtended strand (participates in β ladder)trans-126.4134.3178.500000112.8G30 W31 Y173 A180 N427 F809G30-A175 WeakPolarHBondContact CA-O 3.22Å; W31-A175 HydrophobicContact CE3-CB 4.45Å; W31-A175 PolarHBondContact N-O 3.47Å; W31-A175 PolarHBondContact O-N 2.82Å; Y173-A175 HydrophobicContact CE1-CB 3.6Å; A175-A180 HydrophobicContact CB-CB 4.15Å; A175-N427 PolarHBondContact O-ND2 3.11Å; A175-N427 PolarHBondContact O-OD1 3.29Å; A175-F809 HydrophobicContact CB-CE2 3.98Å; A175-F809 HydrophobicContact CB-CZ 3.57Å
176L98.4Very high98Very high0 Ų014 Ų140%07%0.07CC..EExtended strand (participates in β ladder)trans-145.380.2170-169.768.9000106.7P27 R179 W181 L412 F426 N427P27-L176 HydrophobicContact CB-CD2 4.32Å; P27-L176 HydrophobicContact CG-CB 4.48Å; P27-L176 HydrophobicContact CG-CD2 4.07Å; L176-R179 CarbonylContact C-O 3.55Å; L176-R179 PolarHBondContact N-O 3.37Å; L176-R179 PolarHBondContact O-N 3.13Å; L176-W181 HydrophobicContact CB-CH2 4.45Å; L176-W181 HydrophobicContact CB-CZ3 3.96Å; L176-L412 HydrophobicContact CD1-CD2 4.44Å; L176-L412 HydrophobicContact CD2-CD1 3.86Å; L176-L412 HydrophobicContact CD2-CD2 4.2Å; L176-F426 HydrophobicContact CD1-CB 3.9Å; L176-F426 HydrophobicContact CD1-CD2 3.72Å; L176-F426 HydrophobicContact CD1-CG 4.15Å; L176-F426 HydrophobicContact CG-CB 4.49Å; L176-F426 HydrophobicContact CG-CD2 4.48Å; L176-N427 WeakPolarHBondContact CA-OD1 3.45Å; L176-N427 PolarHBondContact N-OD1 3.27Å
177Y98.7Very high97.5Very high2 Ų216 Ų161%0.0088%0.084CC..THydrogen-bonded Turntrans-49.3133.9-172.6-175.6-92.7000111A97 P98 V201 Q408 N427 L429 A433A97-Y177 HydrophobicContact CB-CD2 4.22Å; P98-Y177 HydrophobicContact CG-CD2 4.43Å; P98-Y177 HydrophobicContact CG-CE2 3.82Å; Y177-V201 HydrophobicContact CE1-CB 4.38Å; Y177-V201 HydrophobicContact CE1-CG1 4.09Å; Y177-V201 WeakPolarHBondContact OH-CG2 3.28Å; Y177-Q408 PolarHBondContact O-NE2 3.49Å; Y177-N427 PolarHBondContact N-OD1 2.91Å; Y177-L429 HydrophobicContact CD1-CB 3.78Å; Y177-L429 HydrophobicContact CE1-CB 4.08Å; Y177-A433 VanDerWaalsContact OH-CB 3.28Å; Y177-A433 WeakPolarHBondContact OH-CB 3.19Å
178P98.6Very high97.3Very high2 Ų216.6 Ų16.61%0.01310%0.101CC..THydrogen-bonded Turncis-9115.516.340.6-43000116S199 V201 I404P178-S199 PolarHBondContact O-N 2.82Å; P178-V201 HydrophobicContact CB-CB 3.89Å; P178-V201 HydrophobicContact CG-CB 4.46Å; P178-V201 WeakPolarHBondContact CG-O 3.36Å; P178-I404 HydrophobicContact CG-CD1 3.64Å; P178-I404 HydrophobicContact CG-CG1 3.87Å; P178-I404 HydrophobicContact CG-CG2 4.01Å
179R98.6Very high97.3Very high10 Ų1018.1 Ų18.14%0.03811%0.106CC..EExtended strand (participates in β ladder)trans-112.4152.3178-64.2177.4-65.2170.5-3.4111.5L176 W181 Q197 I198 I404 E405 Q408L176-R179 CarbonylContact C-O 3.55Å; L176-R179 PolarHBondContact N-O 3.37Å; L176-R179 PolarHBondContact O-N 3.13Å; R179-W181 HydrophobicContact CB-CH2 3.42Å; R179-W181 VanDerWaalsContact CB-CH2 3.42Å; R179-W181 HydrophobicContact CB-CZ2 3.97Å; R179-W181 HydrophobicContact CB-CZ3 3.81Å; R179-W181 HydrophobicContact CG-CH2 4.42Å; R179-Q197 WeakPolarHBondContact CA-O 3.49Å; R179-I198 HydrophobicContact CG-CG1 4.33Å; R179-I198 HydrophobicContact CG-CG2 4.38Å; R179-I404 HydrophobicContact CG-CD1 4.38Å; R179-I404 HydrophobicContact CG-CG2 4.46Å; R179-E405 IonicContact CZ-OE1 2.7Å; R179-E405 VanDerWaalsContact NH1-CG 3.34Å; R179-E405 IonicContact NH1-OE1 2.82Å; R179-E405 PolarHBondContact NH1-OE1 2.59Å; R179-E405 VanDerWaalsContact NH2-CG 3.34Å; R179-Q408 VanDerWaalsContact NH2-OE1 3.11Å
180A98.8Very high97.2Very high0 Ų019.3 Ų19.30%012%0.115CC..EExtended strand (participates in β ladder)trans-145.2162.8165.100000111.2A97 Y173 H174 A175 Q197A97-A180 HydrophobicContact CB-CB 4Å; Y173-A180 HydrophobicContact CE2-CB 3.72Å; Y173-A180 WeakPolarHBondContact OH-CB 3.03Å; H174-A180 CarbonylContact O-C 3.6Å; H174-A180 VanDerWaalsContact O-CA 3.24Å; H174-A180 WeakPolarHBondContact O-CA 3.24Å; H174-A180 WeakPolarHBondContact O-CB 3.25Å; A175-A180 HydrophobicContact CB-CB 4.15Å; A180-Q197 HydrophobicContact CB-CG 3.61Å; A180-Q197 PolarHBondContact N-O 3.34Å; A180-Q197 VanDerWaalsContact N-O 3.1Å; A180-Q197 VanDerWaalsContact O-CG 3.25Å; A180-Q197 WeakPolarHBondContact O-CG 3.41Å; A180-Q197 PolarHBondContact O-N 3.19Å
181W98.8Very high97.2Very high2 Ų215.5 Ų15.51%0.00810%0.1CC..EExtended strand (participates in β ladder)trans-129.5141.2-177-60.7-110.2000109.5G25 V26 P27 Y173 H174 L176 R179 C195 R196G25-W181 PolarHBondContact O-NE1 2.8Å; V26-W181 HydrophobicContact CG1-CG 4.46Å; V26-W181 HydrophobicContact CG2-CB 3.98Å; V26-W181 HydrophobicContact CG2-CG 3.91Å; P27-W181 VanDerWaalsContact CD-CZ2 3.46Å; P27-W181 HydrophobicContact CG-CE3 4.23Å; P27-W181 HydrophobicContact CG-CH2 3.51Å; P27-W181 HydrophobicContact CG-CZ2 3.99Å; P27-W181 HydrophobicContact CG-CZ3 3.64Å; Y173-W181 CarbonylContact C-O 3.6Å; Y173-W181 WeakPolarHBondContact CA-O 3.32Å; Y173-W181 WeakPolarHBondContact CD2-O 3.5Å; H174-W181 HydrophobicContact CB-CB 4.33Å; H174-W181 AromaticContact CD2-CE3 3.72Å; H174-W181 PolarHBondContact N-O 2.8Å; H174-W181 PolarHBondContact O-N 3.28Å; L176-W181 HydrophobicContact CB-CH2 4.45Å; L176-W181 HydrophobicContact CB-CZ3 3.96Å; R179-W181 HydrophobicContact CB-CH2 3.42Å; R179-W181 VanDerWaalsContact CB-CH2 3.42Å; R179-W181 HydrophobicContact CB-CZ2 3.97Å; R179-W181 HydrophobicContact CB-CZ3 3.81Å; R179-W181 HydrophobicContact CG-CH2 4.42Å; W181-C195 CarbonylContact C-O 3.51Å; W181-C195 WeakPolarHBondContact CA-O 3.25Å; W181-R196 VanDerWaalsContact CD1-CG 3.45Å; W181-R196 HydrophobicContact CG-CG 4.47Å
182T98.6Very high97.3Very high1 Ų115.6 Ų15.61%0.00610%0.1CC..EExtended strand (participates in β ladder)trans-122.9121.7162.8-42.10000108.8L35 F172 Y184 C195L35-T182 HydrophobicContact CD1-CG2 4.19Å; L35-T182 HydrophobicContact CD2-CG2 4.32Å; F172-T182 WeakPolarHBondContact O-CA 3.35Å; T182-Y184 HydrophobicContact CG2-CD2 4.14Å; T182-Y184 HydrophobicContact CG2-CE1 4.24Å; T182-Y184 HydrophobicContact CG2-CE2 3.36Å; T182-Y184 VanDerWaalsContact CG2-CZ 3.42Å; T182-Y184 WeakPolarHBondContact CG2-OH 3.39Å; T182-C195 PolarHBondContact N-O 3.05Å; T182-C195 PolarHBondContact O-N 2.94Å
183V98.6Very high97.3Very high0 Ų015.6 Ų15.60%010%0.1CC..EExtended strand (participates in β ladder)trans-106.9126.9-179.1-178.50000108.8V26 A171 F172 T192 L193 T194V26-V183 HydrophobicContact CG2-CG2 3.82Å; A171-V183 CarbonylContact C-O 3.35Å; A171-V183 WeakPolarHBondContact CA-O 3.49Å; A171-V183 WeakPolarHBondContact CB-O 3.37Å; F172-V183 HydrophobicContact CD1-CB 4.04Å; F172-V183 HydrophobicContact CE1-CB 3.63Å; F172-V183 HydrophobicContact CE1-CG1 3.92Å; F172-V183 HydrophobicContact CE1-CG2 3.89Å; F172-V183 HydrophobicContact CE2-CB 4.26Å; F172-V183 HydrophobicContact CE2-CG2 3.85Å; F172-V183 HydrophobicContact CZ-CB 3.76Å; F172-V183 HydrophobicContact CZ-CG1 4.32Å; F172-V183 HydrophobicContact CZ-CG2 3.46Å; F172-V183 VanDerWaalsContact CZ-CG2 3.46Å; F172-V183 PolarHBondContact N-O 2.78Å; F172-V183 VanDerWaalsContact N-O 3.1Å; F172-V183 PolarHBondContact O-N 3.34Å; V183-T192 HydrophobicContact CG1-CG2 3.89Å; V183-L193 CarbonylContact C-O 3.55Å; V183-L193 WeakPolarHBondContact CA-O 3.35Å; V183-T194 HydrophobicContact CG2-CG2 4.01Å
184Y98.4Very high97.3Very high0 Ų015.6 Ų15.60%010%0.1CC..EExtended strand (participates in β ladder)trans-120.8119.6176.7-57.5-96.5000109.3L35 L151 Y166 A171 T182 T192 L193 W218L35-Y184 HydrophobicContact CD2-CE1 4.09Å; L151-Y184 HydrophobicContact CB-CD1 4.41Å; L151-Y184 HydrophobicContact CB-CE1 3.85Å; L151-Y184 HydrophobicContact CB-CE2 4.24Å; L151-Y184 HydrophobicContact CD1-CD2 4.43Å; L151-Y184 HydrophobicContact CD1-CE2 4.34Å; L151-Y184 HydrophobicContact CD2-CD1 4.05Å; L151-Y184 HydrophobicContact CD2-CE1 4.35Å; L151-Y184 HydrophobicContact CD2-CG 4.15Å; L151-Y184 PolarHBondContact O-OH 3.01Å; Y166-Y184 HydrophobicContact CD1-CD1 4.02Å; Y166-Y184 HydrophobicContact CD1-CE1 4.37Å; Y166-Y184 AromaticContact CE1-CD1 3.69Å; Y166-Y184 HydrophobicContact CE1-CD1 3.69Å; Y166-Y184 HydrophobicContact CE1-CE1 4.44Å; Y166-Y184 HydrophobicContact CE2-CD1 4.39Å; Y166-Y184 AromaticContact CZ-CD1 3.86Å; A171-Y184 HydrophobicContact CB-CD1 3.76Å; A171-Y184 HydrophobicContact CB-CE1 4.22Å; A171-Y184 HydrophobicContact CB-CG 4.32Å; T182-Y184 HydrophobicContact CG2-CD2 4.14Å; T182-Y184 HydrophobicContact CG2-CE1 4.24Å; T182-Y184 HydrophobicContact CG2-CE2 3.36Å; T182-Y184 VanDerWaalsContact CG2-CZ 3.42Å; T182-Y184 WeakPolarHBondContact CG2-OH 3.39Å; Y184-T192 WeakPolarHBondContact O-CA 3.42Å; Y184-L193 PolarHBondContact N-O 2.86Å; Y184-L193 PolarHBondContact O-N 2.85Å; Y184-W218 HydrophobicContact CD2-CH2 4.37Å; Y184-W218 HydrophobicContact CD2-CZ3 4.14Å; Y184-W218 AromaticContact CE2-CH2 3.93Å; Y184-W218 HydrophobicContact CE2-CH2 3.93Å; Y184-W218 HydrophobicContact CE2-CZ3 4.16Å
185Q97.4Very high97.3Very high46 Ų4615.6 Ų15.622%0.21510%0.1CC..EExtended strand (participates in β ladder)trans-93.4111.4167-175.3-170.425.200109S19 Y166 Y170 P187S19-Q185 PolarHBondContact OG-OE1 3.46Å; Y166-Q185 PolarHBondContact OH-N 2.95Å; Y166-Q185 PolarHBondContact OH-O 3.21Å; Y170-Q185 PolarHBondContact O-N 3.17Å; Q185-P187 WeakPolarHBondContact O-CD 3.15Å
186L96.6Very high97.3Very high2 Ų217.3 Ų17.31%0.0111%0.106CC..EExtended strand (participates in β ladder)trans-75105.4-176.9-56.9-174000110.4V137 L139 Y147 L151 Y166 G188 Q189 V191 L193V137-L186 HydrophobicContact CG1-CD1 4.14Å; V137-L186 HydrophobicContact CG1-CD2 4.43Å; V137-L186 HydrophobicContact CG2-CD1 4.47Å; L139-L186 HydrophobicContact CD1-CD1 3.9Å; L139-L186 HydrophobicContact CD2-CD1 4.43Å; L139-L186 HydrophobicContact CG-CD1 4.41Å; Y147-L186 HydrophobicContact CD1-CD1 4.25Å; Y147-L186 HydrophobicContact CE1-CB 4.47Å; Y147-L186 HydrophobicContact CE1-CD1 3.99Å; Y147-L186 HydrophobicContact CE1-CD2 4.09Å; Y147-L186 HydrophobicContact CE1-CG 4.42Å; L151-L186 HydrophobicContact CD2-CD2 4.35Å; Y166-L186 HydrophobicContact CE2-CD2 3.95Å; L186-G188 PolarHBondContact O-N 3.01Å; L186-Q189 HydrophobicContact CB-CB 3.9Å; L186-Q189 HydrophobicContact CB-CG 4.04Å; L186-Q189 PolarHBondContact O-N 3.24Å; L186-Q189 VanDerWaalsContact O-N 3.09Å; L186-V191 HydrophobicContact CB-CB 4.49Å; L186-V191 HydrophobicContact CD1-CB 4.12Å; L186-V191 HydrophobicContact CD1-CG1 3.96Å; L186-V191 PolarHBondContact N-O 2.88Å; L186-L193 HydrophobicContact CD1-CD1 4.07Å; L186-L193 HydrophobicContact CD1-CG 4.21Å; L186-L193 HydrophobicContact CD2-CD1 4.2Å; L186-L193 HydrophobicContact CG-CD1 4.37Å; L186-L193 HydrophobicContact CG-CG 4.37Å
187P87.7Confident97.3Very high51 Ų5117.4 Ų17.433%0.33111%0.107SC..THydrogen-bonded Turntrans-64.2131.5-170.4-22.136.4000111.2Y170 Q185 Q189Y170-P187 HydrophobicContact CD1-CG 3.9Å; Y170-P187 HydrophobicContact CD2-CG 3.77Å; Y170-P187 HydrophobicContact CE1-CG 4.25Å; Y170-P187 HydrophobicContact CE2-CG 4.14Å; Y170-P187 HydrophobicContact CG-CG 3.63Å; Q185-P187 WeakPolarHBondContact O-CD 3.15Å; P187-Q189 PolarHBondContact O-N 2.98Å
188G92.2Very high97.3Very high74 Ų7417.3 Ų17.376%0.76311%0.107SC*.THydrogen-bonded Turntrans75.9-1.3-178.600000115.5L186L186-G188 PolarHBondContact O-N 3.01Å
189Q96.2Very high97.3Very high39 Ų3917.2 Ų17.218%0.18211%0.106CC..THydrogen-bonded Turntrans-102.6-11.9178.3-53.8-53.3-5500113.5L139 Y147 L186 P187 V191 N224L139-Q189 HydrophobicContact CD1-CB 3.82Å; L139-Q189 HydrophobicContact CD1-CG 3.95Å; Y147-Q189 HydrophobicContact CD1-CG 4.28Å; Y147-Q189 HydrophobicContact CD2-CG 3.8Å; Y147-Q189 HydrophobicContact CE2-CG 4.21Å; Y147-Q189 HydrophobicContact CG-CG 3.84Å; L186-Q189 HydrophobicContact CB-CB 3.9Å; L186-Q189 HydrophobicContact CB-CG 4.04Å; L186-Q189 PolarHBondContact O-N 3.24Å; L186-Q189 VanDerWaalsContact O-N 3.09Å; P187-Q189 PolarHBondContact O-N 2.98Å; Q189-V191 HydrophobicContact CB-CB 4.46Å; Q189-V191 PolarHBondContact O-N 3.42Å; Q189-N224 PolarHBondContact O-ND2 2.76Å
190N95.3Very high97.2Very high96 Ų9616.7 Ų16.751%0.51310%0.104SC..THydrogen-bonded Turntrans4941.8-171.6-62-29.8000112.5K223N190-K223 HydrophobicContact CB-CB 4.25Å; N190-K223 WeakPolarHBondContact O-CB 3.47Å; N190-K223 PolarHBondContact O-N 2.95Å
191V97.8Very high97.2Very high1 Ų116.8 Ų16.81%0.00611%0.105CC..EExtended strand (participates in β ladder)trans-126.1134.8176.3171.90000108.9L139 L186 Q189 L193 I220 E221 L228L139-V191 HydrophobicContact CD1-CB 4.43Å; L139-V191 HydrophobicContact CD1-CG2 4.14Å; L186-V191 HydrophobicContact CB-CB 4.49Å; L186-V191 HydrophobicContact CD1-CB 4.12Å; L186-V191 HydrophobicContact CD1-CG1 3.96Å; L186-V191 PolarHBondContact N-O 2.88Å; Q189-V191 HydrophobicContact CB-CB 4.46Å; Q189-V191 PolarHBondContact O-N 3.42Å; V191-L193 HydrophobicContact CG1-CD2 3.86Å; V191-L193 HydrophobicContact CG1-CG 4.38Å; V191-I220 HydrophobicContact CG1-CG2 4.15Å; V191-E221 WeakPolarHBondContact CA-O 3.49Å; V191-L228 HydrophobicContact CG2-CD1 3.52Å
192T98.3Very high97.2Very high1 Ų117.2 Ų17.21%0.00611%0.107CC..EExtended strand (participates in β ladder)trans-115.4127.8172.7-45.80000108.3E21 V183 Y184 E221 K223E21-T192 WeakPolarHBondContact OE2-CG2 3.49Å; E21-T192 PolarHBondContact OE2-OG1 2.88Å; V183-T192 HydrophobicContact CG1-CG2 3.89Å; Y184-T192 WeakPolarHBondContact O-CA 3.42Å; T192-E221 PolarHBondContact N-O 2.92Å; T192-E221 VanDerWaalsContact N-O 3.12Å; T192-E221 PolarHBondContact O-N 2.92Å; T192-K223 PolarHBondContact OG1-NZ 3.05Å
193L98.7Very high97.2Very high0 Ų017.9 Ų17.90%011%0.111CC..EExtended strand (participates in β ladder)trans-106.7130.8174.6-54.2178.3000108.8V137 L151 V183 Y184 L186 V191 W218 D219 I220V137-L193 HydrophobicContact CB-CD1 3.88Å; V137-L193 HydrophobicContact CG1-CD1 4.06Å; V137-L193 HydrophobicContact CG2-CD1 3.91Å; L151-L193 HydrophobicContact CD1-CD1 3.95Å; L151-L193 HydrophobicContact CD2-CD1 4.19Å; V183-L193 CarbonylContact C-O 3.55Å; V183-L193 WeakPolarHBondContact CA-O 3.35Å; Y184-L193 PolarHBondContact N-O 2.86Å; Y184-L193 PolarHBondContact O-N 2.85Å; L186-L193 HydrophobicContact CD1-CD1 4.07Å; L186-L193 HydrophobicContact CD1-CG 4.21Å; L186-L193 HydrophobicContact CD2-CD1 4.2Å; L186-L193 HydrophobicContact CG-CD1 4.37Å; L186-L193 HydrophobicContact CG-CG 4.37Å; V191-L193 HydrophobicContact CG1-CD2 3.86Å; V191-L193 HydrophobicContact CG1-CG 4.38Å; L193-W218 HydrophobicContact CB-CE3 4.1Å; L193-W218 HydrophobicContact CB-CZ3 3.99Å; L193-W218 HydrophobicContact CD1-CZ3 4.29Å; L193-D219 WeakPolarHBondContact CA-O 3.33Å; L193-I220 HydrophobicContact CD2-CB 4.27Å; L193-I220 HydrophobicContact CD2-CG1 3.88Å; L193-I220 HydrophobicContact CD2-CG2 3.95Å
194T98.7Very high97.2Very high0 Ų023.3 Ų23.30%014%0.136CC..EExtended strand (participates in β ladder)trans-119.6111.1170.5-56.30000109.2G23 Q24 V26 V183 R196 W218 D219G23-T194 VanDerWaalsContact CA-OG1 3.27Å; G23-T194 WeakPolarHBondContact CA-OG1 3.45Å; Q24-T194 PolarHBondContact N-OG1 3.37Å; Q24-T194 VanDerWaalsContact N-OG1 3.16Å; Q24-T194 WeakPolarHBondContact O-CG2 3.2Å; V26-T194 HydrophobicContact CG2-CG2 4.01Å; V183-T194 HydrophobicContact CG2-CG2 4.01Å; T194-R196 HydrophobicContact CG2-CG 4.27Å; T194-W218 WeakPolarHBondContact O-CA 3.33Å; T194-D219 PolarHBondContact N-O 3.23Å; T194-D219 PolarHBondContact O-N 3.2Å
195C98.8Very high97.2Very high0 Ų025.5 Ų25.50%015%0.148CC..EExtended strand (participates in β ladder)trans-88.8111.3171.7-177.20000109.1W181 T182 V217 W218W181-C195 CarbonylContact C-O 3.51Å; W181-C195 WeakPolarHBondContact CA-O 3.25Å; T182-C195 PolarHBondContact N-O 3.05Å; T182-C195 PolarHBondContact O-N 2.94Å; C195-V217 CarbonylContact C-O 3.59Å; C195-W218 HydrophobicContact CB-CD2 3.83Å; C195-W218 HydrophobicContact CB-CE3 3.75Å; C195-W218 HydrophobicContact CB-CH2 3.47Å; C195-W218 VanDerWaalsContact CB-CH2 3.47Å; C195-W218 HydrophobicContact CB-CZ2 3.52Å; C195-W218 HydrophobicContact CB-CZ3 3.59Å; C195-W218 VanDerWaalsContact SG-CE2 3.52Å; C195-W218 WeakPolarHBondContact SG-CZ2 3.39Å
196R98Very high97.2Very high36 Ų3624.7 Ų24.714%0.13614%0.143CC..EExtended strand (participates in β ladder)trans-92.7119.3169.4-54.4-165.4-91.8132.5-1.7108.6W181 T194 I198 F216 V217 D219 E401W181-R196 VanDerWaalsContact CD1-CG 3.45Å; W181-R196 HydrophobicContact CG-CG 4.47Å; T194-R196 HydrophobicContact CG2-CG 4.27Å; R196-I198 HydrophobicContact CB-CD1 4.1Å; R196-F216 CarbonylContact O-C 3.46Å; R196-F216 VanDerWaalsContact O-CA 3.24Å; R196-F216 WeakPolarHBondContact O-CA 3.32Å; R196-V217 HydrophobicContact CB-CB 4.34Å; R196-V217 PolarHBondContact N-O 2.98Å; R196-V217 PolarHBondContact O-N 3.49Å; R196-D219 IonicContact CZ-OD2 2.93Å; R196-D219 IonicContact NE-OD2 2.76Å; R196-D219 PolarHBondContact NE-OD2 3.02Å; R196-D219 IonicContact NH2-OD1 3.91Å; R196-D219 PolarHBondContact NH2-OD1 3.03Å; R196-D219 IonicContact NH2-OD2 3.48Å; R196-D219 PolarHBondContact NH2-OD2 2.96Å; R196-D219 VanDerWaalsContact NH2-OD2 3.09Å; R196-E401 IonicContact CZ-OE1 3.76Å; R196-E401 VanDerWaalsContact NH1-CD 3.29Å; R196-E401 IonicContact NH1-OE1 3.49Å; R196-E401 PolarHBondContact NH1-OE1 3.04Å; R196-E401 IonicContact NH1-OE2 3.85Å; R196-E401 PolarHBondContact NH1-OE2 3.1Å
197Q98.3Very high97.3Very high2 Ų227.8 Ų27.81%0.00916%0.158CC..EExtended strand (participates in β ladder)trans-100.2131.7169.858.8171.972.600109.9A97 L99 R179 A180 V215 F216A97-Q197 PolarHBondContact O-NE2 3Å; A97-Q197 VanDerWaalsContact O-NE2 3.1Å; L99-Q197 HydrophobicContact CD2-CB 4.03Å; L99-Q197 HydrophobicContact CD2-CG 4.41Å; R179-Q197 WeakPolarHBondContact CA-O 3.49Å; A180-Q197 HydrophobicContact CB-CG 3.61Å; A180-Q197 PolarHBondContact N-O 3.34Å; A180-Q197 VanDerWaalsContact N-O 3.1Å; A180-Q197 VanDerWaalsContact O-CG 3.25Å; A180-Q197 WeakPolarHBondContact O-CG 3.41Å; A180-Q197 PolarHBondContact O-N 3.19Å; Q197-V215 CarbonylContact C-O 3.59Å; Q197-V215 WeakPolarHBondContact CA-O 3.31Å; Q197-F216 HydrophobicContact CB-CD1 3.81Å; Q197-F216 HydrophobicContact CB-CE1 3.86Å
198I98.8Very high97.8Very high0 Ų026 Ų260%015%0.145CC..EExtended strand (participates in β ladder)trans-127.5121.2-175.7-54.196.7000109.5R179 R196 A214 V215 V217 Y397 W400 E401 I404R179-I198 HydrophobicContact CG-CG1 4.33Å; R179-I198 HydrophobicContact CG-CG2 4.38Å; R196-I198 HydrophobicContact CB-CD1 4.1Å; I198-A214 VanDerWaalsContact O-CA 3.3Å; I198-A214 WeakPolarHBondContact O-CA 3.46Å; I198-V215 HydrophobicContact CD1-CB 4.47Å; I198-V215 HydrophobicContact CD1-CG1 4.45Å; I198-V215 PolarHBondContact N-O 2.88Å; I198-V215 PolarHBondContact O-N 2.88Å; I198-V217 HydrophobicContact CD1-CG2 3.97Å; I198-Y397 HydrophobicContact CD1-CD2 4.49Å; I198-W400 HydrophobicContact CG2-CE3 4.49Å; I198-E401 HydrophobicContact CG1-CG 3.99Å; I198-E401 HydrophobicContact CG2-CG 4.28Å; I198-I404 HydrophobicContact CG2-CD1 4.21Å
199S98.4Very high98.1Very high0 Ų022.5 Ų22.50%011%0.109CC..  trans-102.6141.6166.6-61.70000109.8P98 L99 G100 P178 V201P98-S199 PolarHBondContact O-OG 3.14Å; L99-S199 VanDerWaalsContact CA-OG 3.32Å; L99-S199 WeakPolarHBondContact CA-OG 3.46Å; G100-S199 PolarHBondContact N-OG 2.97Å; G100-S199 VanDerWaalsContact N-OG 3.14Å; P178-S199 PolarHBondContact O-N 2.82Å; S199-V201 PolarHBondContact O-N 2.99Å
200P97.8Very high98.2Very high0 Ų020.7 Ų20.70%010%0.101CC..  trans-80.441.8-173.233.7-37000113.7I202 D208 S209 L211 A213 W400P200-I202 PolarHBondContact O-N 3.23Å; P200-D208 HydrophobicContact CB-CB 4.42Å; P200-D208 WeakPolarHBondContact CB-O 3.46Å; P200-D208 VanDerWaalsContact CG-O 3.31Å; P200-D208 WeakPolarHBondContact CG-O 3.09Å; P200-D208 CarbonylContact O-C 3.57Å; P200-D208 VanDerWaalsContact O-C 3.31Å; P200-S209 WeakPolarHBondContact O-CA 3.41Å; P200-S209 PolarHBondContact O-N 2.97Å; P200-L211 HydrophobicContact CG-CB 4.08Å; P200-A213 WeakPolarHBondContact CD-O 3.43Å; P200-W400 HydrophobicContact CB-CD2 3.81Å; P200-W400 HydrophobicContact CB-CE3 3.78Å; P200-W400 HydrophobicContact CB-CG 4.45Å; P200-W400 HydrophobicContact CB-CH2 3.94Å; P200-W400 HydrophobicContact CB-CZ2 3.99Å; P200-W400 HydrophobicContact CB-CZ3 3.85Å; P200-W400 HydrophobicContact CG-CH2 4.25Å; P200-W400 HydrophobicContact CG-CZ3 4.26Å
201V98.6Very high98.4Very high2 Ų216.2 Ų16.21%0.0128%0.077CC..  trans-91.8102.4-177.3177.10000110.7I102 Y177 P178 S199 W500I102-V201 HydrophobicContact CD1-CG1 4.2Å; I102-V201 HydrophobicContact CG1-CG1 4.24Å; I102-V201 HydrophobicContact CG1-CG2 4.29Å; Y177-V201 HydrophobicContact CE1-CB 4.38Å; Y177-V201 HydrophobicContact CE1-CG1 4.09Å; Y177-V201 WeakPolarHBondContact OH-CG2 3.28Å; P178-V201 HydrophobicContact CB-CB 3.89Å; P178-V201 HydrophobicContact CG-CB 4.46Å; P178-V201 WeakPolarHBondContact CG-O 3.36Å; S199-V201 PolarHBondContact O-N 2.99Å; V201-W500 HydrophobicContact CG1-CH2 3.69Å; V201-W500 HydrophobicContact CG1-CZ2 3.44Å; V201-W500 VanDerWaalsContact CG1-CZ2 3.44Å
202I98.6Very high98.4Very high11 Ų1116.1 Ų16.16%0.0568%0.076CC..  trans-127.5122.6-168.4-55166.1000109P200 H204 D205 D208 S209 W400 I404 W500P200-I202 PolarHBondContact O-N 3.23Å; I202-H204 PolarHBondContact O-N 3.38Å; I202-D205 HydrophobicContact CB-CB 3.87Å; I202-D205 HydrophobicContact CG2-CB 4.06Å; I202-D205 PolarHBondContact O-N 2.86Å; I202-D208 HydrophobicContact CD1-CB 4.45Å; I202-S209 PolarHBondContact N-OG 3.2Å; I202-S209 PolarHBondContact O-OG 3.48Å; I202-W400 HydrophobicContact CD1-CB 4.06Å; I202-W400 HydrophobicContact CD1-CG 4.19Å; I202-I404 HydrophobicContact CG1-CG1 4.02Å; I202-W500 PolarHBondContact O-NE1 2.94Å
203P98.4Very high98.4Very high15 Ų1516.1 Ų16.110%0.0978%0.077CC..THydrogen-bonded Turntrans-53.7140.1175.3-2837000112.2D205 W407 L499P203-D205 PolarHBondContact O-N 3.16Å; P203-W407 HydrophobicContact CG-CD2 3.66Å; P203-W407 HydrophobicContact CG-CE3 3.8Å; P203-W407 HydrophobicContact CG-CG 3.99Å; P203-W407 HydrophobicContact CG-CH2 4.3Å; P203-W407 HydrophobicContact CG-CZ2 4.24Å; P203-W407 HydrophobicContact CG-CZ3 4.05Å; P203-L499 CarbonylContact C-O 3.57Å; P203-L499 WeakPolarHBondContact CA-O 3.29Å; P203-L499 HydrophobicContact CB-CB 4.02Å; P203-L499 HydrophobicContact CB-CD2 3.96Å; P203-L499 HydrophobicContact CG-CB 4.24Å; P203-L499 HydrophobicContact CG-CD2 3.84Å; P203-L499 HydrophobicContact CG-CG 4.46Å
204H98Very high98.4Very high114 Ų11416.1 Ų16.153%0.5288%0.077SC..THydrogen-bonded Turntrans60.51.1-177.4-50.1-73.3000116.8I202 Y206 L499I202-H204 PolarHBondContact O-N 3.38Å; H204-Y206 WeakPolarHBondContact O-CD2 3.42Å; H204-Y206 WeakPolarHBondContact O-CE2 3.41Å; H204-L499 PolarHBondContact N-O 3.06Å
205D98.5Very high98.5Very high46 Ų4616.1 Ų16.125%0.2468%0.077CC..  trans-92122.2166.9-167.5-53.9000109.2I202 P203 Q207 D208 S209I202-D205 HydrophobicContact CB-CB 3.87Å; I202-D205 HydrophobicContact CG2-CB 4.06Å; I202-D205 PolarHBondContact O-N 2.86Å; P203-D205 PolarHBondContact O-N 3.16Å; D205-Q207 PolarHBondContact OD1-N 3.31Å; D205-D208 PolarHBondContact OD1-N 3.09Å; D205-S209 WeakPolarHBondContact O-CB 3.21Å; D205-S209 PolarHBondContact O-OG 2.85Å
206Y98.4Very high98.5Very high29 Ų2916.1 Ų16.111%0.1148%0.077CC..SBendtrans-109.65.1-177.6-59.2-80.6000114.1H204 Y378 W439 Y469 W500 P501 K502 L503H204-Y206 WeakPolarHBondContact O-CD2 3.42Å; H204-Y206 WeakPolarHBondContact O-CE2 3.41Å; Y206-Y378 PolarHBondContact O-OH 2.94Å; Y206-W439 AromaticContact CD1-CH2 3.97Å; Y206-W439 HydrophobicContact CD1-CH2 3.97Å; Y206-W439 HydrophobicContact CD1-CZ2 4.28Å; Y206-W439 HydrophobicContact CG-CH2 4.45Å; Y206-W439 VanDerWaalsContact O-CH2 3.23Å; Y206-W439 WeakPolarHBondContact O-CH2 3.46Å; Y206-Y469 AromaticContact CD1-CD1 3.9Å; Y206-Y469 HydrophobicContact CD1-CD1 3.9Å; Y206-Y469 HydrophobicContact CD1-CE1 4.24Å; Y206-Y469 HydrophobicContact CD2-CD1 4.05Å; Y206-Y469 AromaticContact CD2-CE1 3.54Å; Y206-Y469 HydrophobicContact CD2-CE1 3.54Å; Y206-Y469 HydrophobicContact CE1-CD1 4.36Å; Y206-Y469 HydrophobicContact CE2-CD1 4.48Å; Y206-Y469 AromaticContact CE2-CE1 3.94Å; Y206-Y469 HydrophobicContact CE2-CE1 3.94Å; Y206-Y469 AromaticContact CG-CD1 3.73Å; Y206-Y469 HydrophobicContact CG-CD1 3.73Å; Y206-Y469 AromaticContact CG-CE1 3.7Å; Y206-Y469 HydrophobicContact CG-CE1 3.7Å; Y206-W500 HydrophobicContact CE1-CB 4.11Å; Y206-P501 WeakPolarHBondContact OH-CD 3.42Å; Y206-K502 HydrophobicContact CE1-CB 3.77Å; Y206-K502 HydrophobicContact CE1-CG 4.27Å; Y206-K502 HydrophobicContact CE2-CB 4.3Å; Y206-K502 HydrophobicContact CE2-CG 3.91Å; Y206-K502 WeakPolarHBondContact OH-CG 3.35Å; Y206-K502 PolarHBondContact OH-N 2.89Å; Y206-L503 HydrophobicContact CD1-CG 4.32Å; Y206-L503 HydrophobicContact CE1-CG 4.13Å
207Q97.9Very high98.5Very high66 Ų6614.4 Ų14.431%0.3087%0.07SC..SBendtrans-108-62.7175.8171.9174.9-26.900109.7D205 S209 S210 Y378D205-Q207 PolarHBondContact OD1-N 3.31Å; Q207-S209 VanDerWaalsContact C-N 3.3Å; Q207-S209 PolarHBondContact O-N 2.83Å; Q207-S210 WeakPolarHBondContact O-CB 3.38Å; Q207-S210 PolarHBondContact O-N 2.97Å; Q207-S210 PolarHBondContact O-OG 2.99Å; Q207-Y378 HydrophobicContact CB-CD1 4.48Å; Q207-Y378 HydrophobicContact CB-CD2 4.45Å; Q207-Y378 HydrophobicContact CB-CE1 3.98Å; Q207-Y378 HydrophobicContact CB-CE2 3.98Å; Q207-Y378 HydrophobicContact CG-CD1 3.83Å; Q207-Y378 HydrophobicContact CG-CD2 3.82Å; Q207-Y378 HydrophobicContact CG-CE1 3.85Å; Q207-Y378 HydrophobicContact CG-CE2 3.87Å; Q207-Y378 HydrophobicContact CG-CG 3.82Å
208D98.6Very high98.5Very high14 Ų1414.3 Ų14.38%0.0757%0.07CC..G310 helixtrans-65.9-38.1-175.9-73.1-4000110.6P200 I202 D205 S210 L211 Y392 W400P200-D208 HydrophobicContact CB-CB 4.42Å; P200-D208 WeakPolarHBondContact CB-O 3.46Å; P200-D208 VanDerWaalsContact CG-O 3.31Å; P200-D208 WeakPolarHBondContact CG-O 3.09Å; P200-D208 CarbonylContact O-C 3.57Å; P200-D208 VanDerWaalsContact O-C 3.31Å; I202-D208 HydrophobicContact CD1-CB 4.45Å; D205-D208 PolarHBondContact OD1-N 3.09Å; D208-S210 PolarHBondContact O-N 2.83Å; D208-L211 HydrophobicContact CB-CD1 4.47Å; D208-L211 WeakPolarHBondContact O-CB 3.35Å; D208-L211 WeakPolarHBondContact O-CG 3.38Å; D208-L211 PolarHBondContact O-N 3.42Å; D208-Y392 WeakPolarHBondContact OD1-CE1 3.33Å; D208-Y392 PolarHBondContact OD1-OH 3.43Å; D208-W400 VanDerWaalsContact OD2-CD1 3.31Å; D208-W400 PolarHBondContact OD2-NE1 3.09Å
209S98.7Very high98.5Very high0 Ų014.7 Ų14.70%07%0.072CC..G310 helixtrans-60.2-15172.2-61.40000114.3G101 I102 P200 I202 D205 Q207G101-S209 CarbonylContact C-O 3.48Å; G101-S209 VanDerWaalsContact CA-O 3.29Å; G101-S209 WeakPolarHBondContact CA-O 3.3Å; I102-S209 WeakPolarHBondContact CA-O 3.39Å; I102-S209 WeakPolarHBondContact CB-O 3.4Å; I102-S209 PolarHBondContact N-O 3.02Å; P200-S209 WeakPolarHBondContact O-CA 3.41Å; P200-S209 PolarHBondContact O-N 2.97Å; I202-S209 PolarHBondContact N-OG 3.2Å; I202-S209 PolarHBondContact O-OG 3.48Å; D205-S209 WeakPolarHBondContact O-CB 3.21Å; D205-S209 PolarHBondContact O-OG 2.85Å; Q207-S209 VanDerWaalsContact C-N 3.3Å; Q207-S209 PolarHBondContact O-N 2.83Å
210S98.6Very high98.5Very high1 Ų114.7 Ų14.71%0.0077%0.072CC..G310 helixtrans-90.8-9.8177.176.70000114I102 Q207 D208I102-S210 WeakPolarHBondContact O-CA 3.37Å; Q207-S210 WeakPolarHBondContact O-CB 3.38Å; Q207-S210 PolarHBondContact O-N 2.97Å; Q207-S210 PolarHBondContact O-OG 2.99Å; D208-S210 PolarHBondContact O-N 2.83Å
211L98.7Very high98.5Very high2 Ų216.4 Ų16.41%0.018%0.079CC..  trans-77.2131.3-162.7-57.6-177.9000113.1G101 P200 D208 A213 F379 L389 Y392 W400G101-L211 WeakPolarHBondContact CA-O 3.42Å; G101-L211 PolarHBondContact N-O 2.92Å; P200-L211 HydrophobicContact CG-CB 4.08Å; D208-L211 HydrophobicContact CB-CD1 4.47Å; D208-L211 WeakPolarHBondContact O-CB 3.35Å; D208-L211 WeakPolarHBondContact O-CG 3.38Å; D208-L211 PolarHBondContact O-N 3.42Å; L211-A213 PolarHBondContact O-N 2.99Å; L211-F379 HydrophobicContact CD1-CE2 4.38Å; L211-F379 HydrophobicContact CD2-CD2 3.92Å; L211-F379 HydrophobicContact CD2-CE2 3.42Å; L211-F379 VanDerWaalsContact CD2-CE2 3.42Å; L211-F379 HydrophobicContact CD2-CZ 4.33Å; L211-L389 HydrophobicContact CD2-CD2 4.27Å; L211-Y392 HydrophobicContact CD1-CD1 3.81Å; L211-Y392 HydrophobicContact CD1-CE1 3.83Å; L211-W400 HydrophobicContact CD1-CH2 4.45Å; L211-W400 HydrophobicContact CD1-CZ2 3.97Å
212P98.5Very high98.5Very high0 Ų016.4 Ų16.40%08%0.08CC..  trans-8260.9177.236.3-38.5000111.3A356 W357 Y375 L389P212-A356 WeakPolarHBondContact O-CA 3.41Å; P212-W357 HydrophobicContact CB-CD2 4.12Å; P212-W357 HydrophobicContact CB-CG 4.03Å; P212-W357 HydrophobicContact CB-CZ2 4.25Å; P212-W357 VanDerWaalsContact CB-NE1 3.26Å; P212-W357 WeakPolarHBondContact CB-O 3.39Å; P212-W357 WeakPolarHBondContact CG-O 3.09Å; P212-W357 PolarHBondContact O-N 3.22Å; P212-Y375 HydrophobicContact CB-CE1 4.46Å; P212-Y375 HydrophobicContact CG-CD1 3.85Å; P212-Y375 HydrophobicContact CG-CD2 4.11Å; P212-Y375 HydrophobicContact CG-CE1 3.71Å; P212-Y375 HydrophobicContact CG-CE2 4.03Å; P212-Y375 HydrophobicContact CG-CG 4.03Å; P212-L389 HydrophobicContact CG-CD1 4Å
213A98.6Very high98.4Very high1 Ų119.3 Ų19.31%0.0089%0.092CC..EExtended strand (participates in β ladder)trans-145.4155.5-177.600000112.3P200 L211 L355 A356 A393P200-A213 WeakPolarHBondContact CD-O 3.43Å; L211-A213 PolarHBondContact O-N 2.99Å; A213-L355 CarbonylContact C-O 3.57Å; A213-L355 VanDerWaalsContact CA-O 3.32Å; A213-L355 WeakPolarHBondContact CA-O 3.34Å; A213-A356 HydrophobicContact CB-CB 4.13Å; A213-A393 HydrophobicContact CB-CB 4.26Å
214A98.7Very high98.3Very high0 Ų019 Ų190%09%0.089CC..EExtended strand (participates in β ladder)trans-141.2151.5167.400000110.8L99 I198 C354 L355L99-A214 HydrophobicContact CB-CB 3.83Å; L99-A214 HydrophobicContact CD2-CB 3.86Å; L99-A214 HydrophobicContact CG-CB 4.28Å; I198-A214 VanDerWaalsContact O-CA 3.3Å; I198-A214 WeakPolarHBondContact O-CA 3.46Å; A214-C354 WeakPolarHBondContact O-CA 3.07Å; A214-C354 PolarHBondContact O-SG 2.91Å; A214-L355 PolarHBondContact N-O 3.49Å; A214-L355 PolarHBondContact O-N 2.85Å
215V98.9Very high98.3Very high0 Ų020.1 Ų20.10%010%0.099CC..EExtended strand (participates in β ladder)trans-112.8140.4177175.80000109.8Q197 I198 V217 F353 A393 Y397 W400Q197-V215 CarbonylContact C-O 3.59Å; Q197-V215 WeakPolarHBondContact CA-O 3.31Å; I198-V215 HydrophobicContact CD1-CB 4.47Å; I198-V215 HydrophobicContact CD1-CG1 4.45Å; I198-V215 PolarHBondContact N-O 2.88Å; I198-V215 PolarHBondContact O-N 2.88Å; V215-V217 HydrophobicContact CG1-CG2 3.94Å; V215-F353 CarbonylContact C-O 3.48Å; V215-F353 WeakPolarHBondContact CA-O 3.49Å; V215-F353 WeakPolarHBondContact CG1-O 3.46Å; V215-A393 HydrophobicContact CG2-CB 3.89Å; V215-Y397 HydrophobicContact CB-CG 4.35Å; V215-Y397 HydrophobicContact CG1-CD1 4.01Å; V215-Y397 HydrophobicContact CG1-CD2 4.23Å; V215-Y397 HydrophobicContact CG1-CE1 4.47Å; V215-Y397 HydrophobicContact CG1-CG 3.86Å; V215-Y397 HydrophobicContact CG2-CG 4.4Å; V215-W400 HydrophobicContact CG2-CZ3 4.22Å
216F98.9Very high98.2Very high0 Ų021.5 Ų21.50%010%0.102CC..EExtended strand (participates in β ladder)trans-116.4115.4171.1-53.9-88.3000109.2L99 F115 F135 R196 Q197 F234 F353 L355L99-F216 HydrophobicContact CD1-CE1 4.17Å; L99-F216 HydrophobicContact CD1-CZ 3.58Å; L99-F216 HydrophobicContact CD2-CE1 4.23Å; L99-F216 HydrophobicContact CD2-CZ 4.25Å; F115-F216 HydrophobicContact CE1-CZ 4.33Å; F115-F216 HydrophobicContact CZ-CZ 4.23Å; F135-F216 HydrophobicContact CE2-CD1 4.06Å; F135-F216 HydrophobicContact CE2-CD2 4.43Å; F135-F216 HydrophobicContact CE2-CE1 4.21Å; F135-F216 HydrophobicContact CE2-CG 4.15Å; F135-F216 HydrophobicContact CE2-CZ 4.44Å; F135-F216 HydrophobicContact CZ-CB 3.97Å; F135-F216 HydrophobicContact CZ-CD1 4.06Å; F135-F216 AromaticContact CZ-CD2 3.8Å; F135-F216 HydrophobicContact CZ-CD2 3.8Å; F135-F216 HydrophobicContact CZ-CE1 4.49Å; F135-F216 HydrophobicContact CZ-CE2 4.25Å; F135-F216 AromaticContact CZ-CG 3.68Å; F135-F216 HydrophobicContact CZ-CG 3.68Å; R196-F216 CarbonylContact O-C 3.46Å; R196-F216 VanDerWaalsContact O-CA 3.24Å; R196-F216 WeakPolarHBondContact O-CA 3.32Å; Q197-F216 HydrophobicContact CB-CD1 3.81Å; Q197-F216 HydrophobicContact CB-CE1 3.86Å; F216-F234 HydrophobicContact CD2-CE1 4.37Å; F216-F234 HydrophobicContact CE2-CE1 4.13Å; F216-F234 HydrophobicContact CE2-CZ 4.17Å; F216-F353 HydrophobicContact CB-CB 4.29Å; F216-F353 PolarHBondContact N-O 3.32Å; F216-F353 PolarHBondContact O-N 3.33Å; F216-L355 HydrophobicContact CE2-CB 3.92Å
217V98.7Very high98.2Very high0 Ų022.6 Ų22.60%012%0.116CC..EExtended strand (participates in β ladder)trans-104.6122.6173.3-1710000108.6C195 R196 I198 V215 L351 E352 Y397C195-V217 CarbonylContact C-O 3.59Å; R196-V217 HydrophobicContact CB-CB 4.34Å; R196-V217 PolarHBondContact N-O 2.98Å; R196-V217 PolarHBondContact O-N 3.49Å; I198-V217 HydrophobicContact CD1-CG2 3.97Å; V215-V217 HydrophobicContact CG1-CG2 3.94Å; V217-L351 CarbonylContact C-O 3.58Å; V217-L351 WeakPolarHBondContact CA-O 3.4Å; V217-E352 HydrophobicContact CG1-CG 4.47Å; V217-Y397 HydrophobicContact CG2-CD2 4.1Å; V217-Y397 HydrophobicContact CG2-CE2 3.47Å; V217-Y397 VanDerWaalsContact CG2-CE2 3.47Å
218W98.7Very high98.2Very high0 Ų019.7 Ų19.70%010%0.103CC..EExtended strand (participates in β ladder)trans-103.9102.7178.3-75.491.5000109.8F135 L151 Y184 L193 T194 C195 I232 S350 L351 F353F135-W218 HydrophobicContact CB-CH2 4.12Å; F135-W218 HydrophobicContact CB-CZ2 3.52Å; F135-W218 AromaticContact CD1-CE2 3.81Å; F135-W218 AromaticContact CD1-CZ2 3.78Å; F135-W218 HydrophobicContact CD1-CZ2 3.78Å; F135-W218 AromaticContact CD1-NE1 3.4Å; F135-W218 AromaticContact CD2-CZ2 3.79Å; F135-W218 HydrophobicContact CD2-CZ2 3.79Å; F135-W218 HydrophobicContact CE1-CZ2 4.41Å; F135-W218 AromaticContact CE1-NE1 3.34Å; F135-W218 VanDerWaalsContact CE1-NE1 3.34Å; F135-W218 HydrophobicContact CE2-CZ2 4.42Å; F135-W218 AromaticContact CG-CE2 3.95Å; F135-W218 HydrophobicContact CG-CH2 4.45Å; F135-W218 AromaticContact CG-CZ2 3.42Å; F135-W218 HydrophobicContact CG-CZ2 3.42Å; F135-W218 VanDerWaalsContact CG-CZ2 3.42Å; F135-W218 AromaticContact CG-NE1 3.96Å; F135-W218 AromaticContact CZ-NE1 3.88Å; L151-W218 HydrophobicContact CD1-CH2 3.24Å; L151-W218 HydrophobicContact CD1-CZ2 4.17Å; L151-W218 HydrophobicContact CD1-CZ3 3.48Å; L151-W218 VanDerWaalsContact CD1-CZ3 3.48Å; Y184-W218 HydrophobicContact CD2-CH2 4.37Å; Y184-W218 HydrophobicContact CD2-CZ3 4.14Å; Y184-W218 AromaticContact CE2-CH2 3.93Å; Y184-W218 HydrophobicContact CE2-CH2 3.93Å; Y184-W218 HydrophobicContact CE2-CZ3 4.16Å; L193-W218 HydrophobicContact CB-CE3 4.1Å; L193-W218 HydrophobicContact CB-CZ3 3.99Å; L193-W218 HydrophobicContact CD1-CZ3 4.29Å; T194-W218 WeakPolarHBondContact O-CA 3.33Å; C195-W218 HydrophobicContact CB-CD2 3.83Å; C195-W218 HydrophobicContact CB-CE3 3.75Å; C195-W218 HydrophobicContact CB-CH2 3.47Å; C195-W218 VanDerWaalsContact CB-CH2 3.47Å; C195-W218 HydrophobicContact CB-CZ2 3.52Å; C195-W218 HydrophobicContact CB-CZ3 3.59Å; C195-W218 VanDerWaalsContact SG-CE2 3.52Å; C195-W218 WeakPolarHBondContact SG-CZ2 3.39Å; W218-I232 HydrophobicContact CB-CD1 3.39Å; W218-I232 HydrophobicContact CD2-CD1 3.56Å; W218-I232 HydrophobicContact CD2-CG2 4.46Å; W218-I232 HydrophobicContact CE3-CD1 3.78Å; W218-I232 HydrophobicContact CG-CD1 3.4Å; W218-I232 HydrophobicContact CG-CG2 4.47Å; W218-S350 CarbonylContact O-C 3.49Å; W218-S350 WeakPolarHBondContact O-CA 3.48Å; W218-L351 HydrophobicContact CB-CB 4.31Å; W218-L351 PolarHBondContact N-O 2.91Å; W218-L351 PolarHBondContact O-N 3.32Å; W218-F353 AromaticContact CD1-CD2 3.78Å; W218-F353 AromaticContact CD1-CE2 3.91Å
219D98.5Very high98.2Very high8 Ų822.1 Ų22.14%0.04312%0.116CC..EExtended strand (participates in β ladder)trans-82.6127170.9-63.6-57.6000109.4Q24 L193 T194 R196 L348Q24-D219 HydrophobicContact CB-CB 3.93Å; Q24-D219 HydrophobicContact CG-CB 4.14Å; L193-D219 WeakPolarHBondContact CA-O 3.33Å; T194-D219 PolarHBondContact N-O 3.23Å; T194-D219 PolarHBondContact O-N 3.2Å; R196-D219 IonicContact CZ-OD2 2.93Å; R196-D219 IonicContact NE-OD2 2.76Å; R196-D219 PolarHBondContact NE-OD2 3.02Å; R196-D219 IonicContact NH2-OD1 3.91Å; R196-D219 PolarHBondContact NH2-OD1 3.03Å; R196-D219 IonicContact NH2-OD2 3.48Å; R196-D219 PolarHBondContact NH2-OD2 2.96Å; R196-D219 VanDerWaalsContact NH2-OD2 3.09Å; D219-L348 HydrophobicContact CB-CD1 4.19Å
220I98.5Very high98.2Very high0 Ų022.1 Ų22.10%012%0.116CC..EExtended strand (participates in β ladder)trans-118106.5-173.9-56.4156.1000108.3V191 L193 V230 I232 V343 L348 N349 L351V191-I220 HydrophobicContact CG1-CG2 4.15Å; L193-I220 HydrophobicContact CD2-CB 4.27Å; L193-I220 HydrophobicContact CD2-CG1 3.88Å; L193-I220 HydrophobicContact CD2-CG2 3.95Å; I220-V230 HydrophobicContact CD1-CB 4.17Å; I220-V230 HydrophobicContact CD1-CG1 3.75Å; I220-V230 HydrophobicContact CG1-CG1 4.37Å; I220-V230 HydrophobicContact CG2-CB 4.48Å; I220-V230 HydrophobicContact CG2-CG1 4.23Å; I220-V230 HydrophobicContact CG2-CG2 4.13Å; I220-I232 HydrophobicContact CD1-CD1 4.37Å; I220-V343 HydrophobicContact CB-CG2 4.35Å; I220-V343 HydrophobicContact CG2-CG2 3.97Å; I220-L348 WeakPolarHBondContact O-CA 3.38Å; I220-N349 PolarHBondContact N-O 2.9Å; I220-N349 PolarHBondContact O-N 3.41Å; I220-N349 VanDerWaalsContact O-N 3.1Å; I220-L351 HydrophobicContact CD1-CD1 3.95Å; I220-L351 HydrophobicContact CD1-CG 3.89Å
221E98.1Very high98.2Very high35 Ų3522.2 Ų22.216%0.16412%0.117CC..EExtended strand (participates in β ladder)trans-92.1108.5176.4-63.8169.6-117.700109.8Q24 V191 T192 K223 L348Q24-E221 PolarHBondContact N-OE1 2.83Å; V191-E221 WeakPolarHBondContact CA-O 3.49Å; T192-E221 PolarHBondContact N-O 2.92Å; T192-E221 VanDerWaalsContact N-O 3.12Å; T192-E221 PolarHBondContact O-N 2.92Å; E221-K223 VanDerWaalsContact OE2-CE 3.32Å; E221-K223 WeakPolarHBondContact OE2-CE 3.31Å; E221-K223 IonicContact OE2-NZ 3.01Å; E221-K223 PolarHBondContact OE2-NZ 2.97Å; E221-K223 VanDerWaalsContact OE2-NZ 3.12Å; E221-L348 HydrophobicContact CB-CD1 4.25Å; E221-L348 HydrophobicContact CG-CD1 3.37Å
222N97.9Very high98.2Very high3 Ų322.1 Ų22.12%0.01612%0.116CC..EExtended strand (participates in β ladder)trans-91.2110.2172.5-179.411.8000110.1N224 Y226 V343 P344 L346 K347N222-N224 VanDerWaalsContact OD1-CB 3.28Å; N222-N224 WeakPolarHBondContact OD1-CB 3.23Å; N222-N224 PolarHBondContact OD1-N 3.31Å; N222-N224 PolarHBondContact OD1-ND2 2.98Å; N222-Y226 PolarHBondContact ND2-O 3.44Å; N222-V343 HydrophobicContact CB-CB 4.18Å; N222-V343 HydrophobicContact CB-CG1 3.53Å; N222-V343 PolarHBondContact ND2-O 3.02Å; N222-P344 PolarHBondContact ND2-O 2.66Å; N222-L346 CarbonylContact O-C 3.55Å; N222-L346 WeakPolarHBondContact O-CA 3.41Å; N222-L346 PolarHBondContact O-N 2.91Å; N222-L346 VanDerWaalsContact O-N 3.13Å; N222-K347 PolarHBondContact N-O 3.45Å; N222-K347 PolarHBondContact O-N 3.28Å
223K96.3Very high98.2Very high72 Ų7222.1 Ų22.131%0.31312%0.116SC..  trans-99.37.2-179.7-63.9164.3178157.60112.7E21 N190 T192 E221 L346E21-K223 IonicContact OE1-NZ 3.14Å; E21-K223 PolarHBondContact OE1-NZ 2.93Å; E21-K223 IonicContact OE2-NZ 3.84Å; E21-K223 PolarHBondContact OE2-NZ 3.11Å; N190-K223 HydrophobicContact CB-CB 4.25Å; N190-K223 WeakPolarHBondContact O-CB 3.47Å; N190-K223 PolarHBondContact O-N 2.95Å; T192-K223 PolarHBondContact OG1-NZ 3.05Å; E221-K223 VanDerWaalsContact OE2-CE 3.32Å; E221-K223 WeakPolarHBondContact OE2-CE 3.31Å; E221-K223 IonicContact OE2-NZ 3.01Å; E221-K223 PolarHBondContact OE2-NZ 2.97Å; E221-K223 VanDerWaalsContact OE2-NZ 3.12Å; K223-L346 WeakPolarHBondContact O-CD2 3.35Å
224N97.7Very high98.2Very high8 Ų822.1 Ų22.14%0.04312%0.116CC..SBendtrans-77.8161.3171.9-58.8-79.9000110.9Q189 N222 Y226 A345 L346Q189-N224 PolarHBondContact O-ND2 2.76Å; N222-N224 VanDerWaalsContact OD1-CB 3.28Å; N222-N224 WeakPolarHBondContact OD1-CB 3.23Å; N222-N224 PolarHBondContact OD1-N 3.31Å; N222-N224 PolarHBondContact OD1-ND2 2.98Å; N224-Y226 HydrophobicContact CB-CD1 4.09Å; N224-Y226 HydrophobicContact CB-CD2 3.94Å; N224-Y226 HydrophobicContact CB-CE1 3.88Å; N224-Y226 HydrophobicContact CB-CE2 3.7Å; N224-Y226 HydrophobicContact CB-CG 4.13Å; N224-Y226 PolarHBondContact O-N 3.43Å; N224-Y226 PolarHBondContact OD1-OH 3.25Å; N224-A345 CarbonylContact O-C 3.52Å; N224-A345 WeakPolarHBondContact O-CA 3.47Å; N224-L346 WeakPolarHBondContact O-CD2 3.21Å; N224-L346 PolarHBondContact O-N 2.94Å
225D97.2Very high98.2Very high137 Ų13722.1 Ų22.173%0.73312%0.116SC*.SBendtrans-82.64.3171.263.1-13.8000113.1A345D225-A345 WeakPolarHBondContact O-CB 3.29Å
226Y97.2Very high98.2Very high76 Ų7622.1 Ų22.130%0.29812%0.116SC..SBendtrans-125.8156174.352.1-101.1000112.1R141 N222 N224 L228R141-Y226 HydrophobicContact CG-CD2 4.46Å; N222-Y226 PolarHBondContact ND2-O 3.44Å; N224-Y226 HydrophobicContact CB-CD1 4.09Å; N224-Y226 HydrophobicContact CB-CD2 3.94Å; N224-Y226 HydrophobicContact CB-CE1 3.88Å; N224-Y226 HydrophobicContact CB-CE2 3.7Å; N224-Y226 HydrophobicContact CB-CG 4.13Å; N224-Y226 PolarHBondContact O-N 3.43Å; N224-Y226 PolarHBondContact OD1-OH 3.25Å; Y226-L228 HydrophobicContact CD2-CD2 4.23Å; Y226-L228 HydrophobicContact CD2-CG 4.25Å; Y226-L228 HydrophobicContact CE2-CD2 3.83Å; Y226-L228 HydrophobicContact CE2-CG 4.07Å
227A97.7Very high98.2Very high51 Ų5122.3 Ų22.342%0.42112%0.117SC..  trans-72.1150.8173.500000111.8V343A227-V343 WeakPolarHBondContact CA-O 3.38Å
228L98.1Very high98.1Very high5 Ų522.4 Ų22.43%0.02612%0.118CC..EExtended strand (participates in β ladder)trans-127.4140.8176.2-76.3171.1000109.5R140 R141 V191 Y226 V230 V343R140-L228 WeakPolarHBondContact O-CD2 3.09Å; R141-L228 HydrophobicContact CB-CD2 4.24Å; V191-L228 HydrophobicContact CG2-CD1 3.52Å; Y226-L228 HydrophobicContact CD2-CD2 4.23Å; Y226-L228 HydrophobicContact CD2-CG 4.25Å; Y226-L228 HydrophobicContact CE2-CD2 3.83Å; Y226-L228 HydrophobicContact CE2-CG 4.07Å; L228-V230 HydrophobicContact CB-CG2 4.06Å; L228-V343 PolarHBondContact N-O 3.12Å; L228-V343 PolarHBondContact O-N 2.95Å
229D98.2Very high97.9Very high65 Ų6522.4 Ų22.435%0.34812%0.118SC..EExtended strand (participates in β ladder)trans-93124.4164-55.9-43.4000107.6R140 C341 S342R140-D229 HydrophobicContact CB-CB 4.13Å; R140-D229 PolarHBondContact N-O 2.64Å; R140-D229 PolarHBondContact O-N 3.15Å; D229-C341 WeakPolarHBondContact CA-O 3.45Å; D229-S342 WeakPolarHBondContact OD1-CB 3.33Å; D229-S342 PolarHBondContact OD1-OG 3.2Å
230V98.6Very high97.6Very high1 Ų122.4 Ų22.41%0.00612%0.118CC..EExtended strand (participates in β ladder)trans-122.2123.8-172.1-178.50000109.3V137 C138 L139 I220 L228 S340 C341 V343V137-V230 HydrophobicContact CG2-CG1 4.13Å; C138-V230 WeakPolarHBondContact O-CA 3.25Å; L139-V230 HydrophobicContact CD2-CB 4.28Å; L139-V230 HydrophobicContact CD2-CG1 3.85Å; L139-V230 HydrophobicContact CD2-CG2 3.68Å; I220-V230 HydrophobicContact CD1-CB 4.17Å; I220-V230 HydrophobicContact CD1-CG1 3.75Å; I220-V230 HydrophobicContact CG1-CG1 4.37Å; I220-V230 HydrophobicContact CG2-CB 4.48Å; I220-V230 HydrophobicContact CG2-CG1 4.23Å; I220-V230 HydrophobicContact CG2-CG2 4.13Å; L228-V230 HydrophobicContact CB-CG2 4.06Å; V230-S340 CarbonylContact O-C 3.56Å; V230-S340 VanDerWaalsContact O-CA 3.31Å; V230-S340 WeakPolarHBondContact O-CA 3.3Å; V230-C341 PolarHBondContact N-O 3.4Å; V230-C341 PolarHBondContact O-N 2.9Å; V230-V343 HydrophobicContact CB-CG2 4.26Å; V230-V343 HydrophobicContact CG2-CG2 3.87Å
231S98.7Very high97.2Very high3 Ų322.6 Ų22.62%0.02112%0.12CC..EExtended strand (participates in β ladder)trans-111.8137.1172.1-52.20000110.4V137 C138 G315 V339 S340V137-S231 CarbonylContact C-O 3.55Å; V137-S231 WeakPolarHBondContact CA-O 3.2Å; C138-S231 PolarHBondContact N-O 3.22Å; C138-S231 PolarHBondContact O-N 3.16Å; S231-G315 VanDerWaalsContact CB-O 3.28Å; S231-G315 WeakPolarHBondContact CB-O 3.43Å; S231-G315 PolarHBondContact OG-O 2.93Å; S231-V339 WeakPolarHBondContact CA-O 3.34Å; S231-S340 VanDerWaalsContact OG-CB 3.29Å; S231-S340 WeakPolarHBondContact OG-CB 3.41Å
232I98.8Very high96.8Very high0 Ų023.7 Ų23.70%013%0.125CC..EExtended strand (participates in β ladder)trans-116.5125.2168.7-64-179.1000107.9F135 T136 W218 I220 A338 V339 L351 F353F135-I232 HydrophobicContact CD1-CG2 3.81Å; T136-I232 CarbonylContact O-C 3.57Å; T136-I232 WeakPolarHBondContact O-CA 3.45Å; W218-I232 HydrophobicContact CB-CD1 3.39Å; W218-I232 HydrophobicContact CD2-CD1 3.56Å; W218-I232 HydrophobicContact CD2-CG2 4.46Å; W218-I232 HydrophobicContact CE3-CD1 3.78Å; W218-I232 HydrophobicContact CG-CD1 3.4Å; W218-I232 HydrophobicContact CG-CG2 4.47Å; I220-I232 HydrophobicContact CD1-CD1 4.37Å; I232-A338 VanDerWaalsContact O-CA 3.3Å; I232-A338 WeakPolarHBondContact O-CA 3.44Å; I232-V339 PolarHBondContact N-O 3.41Å; I232-V339 PolarHBondContact O-N 2.8Å; I232-L351 HydrophobicContact CB-CD1 3.94Å; I232-L351 HydrophobicContact CD1-CD1 4.01Å; I232-L351 HydrophobicContact CG1-CD1 3.86Å; I232-F353 HydrophobicContact CB-CE2 4.11Å; I232-F353 HydrophobicContact CB-CZ 4.02Å; I232-F353 HydrophobicContact CG2-CE2 3.93Å; I232-F353 HydrophobicContact CG2-CZ 3.94Å; I232-F353 VanDerWaalsContact O-CZ 3.28Å; I232-F353 WeakPolarHBondContact O-CZ 3.12Å
233M98.8Very high96.5Very high0 Ų031 Ų310%016%0.157CC..EExtended strand (participates in β ladder)trans-103.9128.3175.3179-177.167.600109.8F135 T136 T235 L307 L311 L317 A336 L337 A338F135-M233 CarbonylContact C-O 3.59Å; F135-M233 VanDerWaalsContact CA-O 3.28Å; F135-M233 WeakPolarHBondContact CA-O 3.32Å; T136-M233 HydrophobicContact CG2-CE 4.32Å; T136-M233 PolarHBondContact N-O 2.95Å; T136-M233 PolarHBondContact O-N 2.79Å; M233-T235 HydrophobicContact CE-CG2 3.87Å; M233-T235 HydrophobicContact CG-CG2 4.12Å; M233-T235 HydrophobicContact SD-CG2 4.04Å; M233-L307 HydrophobicContact CE-CD2 4.46Å; M233-L307 HydrophobicContact SD-CD1 4.4Å; M233-L307 HydrophobicContact SD-CD2 4.12Å; M233-L307 HydrophobicContact SD-CG 4.12Å; M233-L311 HydrophobicContact CB-CD2 3.86Å; M233-L311 HydrophobicContact CE-CD2 4.33Å; M233-L311 HydrophobicContact SD-CD2 4.23Å; M233-L317 HydrophobicContact CG-CD1 4.17Å; M233-L317 HydrophobicContact SD-CD1 4.09Å; M233-L317 HydrophobicContact SD-CD2 4.08Å; M233-A336 HydrophobicContact CG-CB 4.24Å; M233-A336 HydrophobicContact SD-CB 4.09Å; M233-L337 CarbonylContact C-O 3.56Å; M233-L337 WeakPolarHBondContact CA-O 3.41Å; M233-A338 HydrophobicContact CB-CB 4.24Å
234F98.8Very high96.3Very high0 Ų030 Ų300%016%0.155CC..EExtended strand (participates in β ladder)trans-107.4120.9171.4-173.6-163.5000109.9F115 Q134 F135 F216 M236 I282 A336 L337 F353 L355F115-F234 HydrophobicContact CE2-CE2 4.09Å; F115-F234 AromaticContact CZ-CE2 3.79Å; F115-F234 HydrophobicContact CZ-CE2 3.79Å; F115-F234 AromaticContact CZ-CZ 3.97Å; F115-F234 HydrophobicContact CZ-CZ 3.97Å; Q134-F234 WeakPolarHBondContact O-CA 3.41Å; Q134-F234 WeakPolarHBondContact O-CD2 3.5Å; F135-F234 HydrophobicContact CD1-CB 3.88Å; F135-F234 HydrophobicContact CD1-CD2 4.18Å; F135-F234 HydrophobicContact CD1-CG 4.1Å; F135-F234 HydrophobicContact CD2-CD2 4.35Å; F135-F234 HydrophobicContact CE1-CB 3.57Å; F135-F234 AromaticContact CE1-CD1 3.92Å; F135-F234 HydrophobicContact CE1-CD1 3.92Å; F135-F234 AromaticContact CE1-CD2 3.81Å; F135-F234 HydrophobicContact CE1-CD2 3.81Å; F135-F234 HydrophobicContact CE1-CE2 4.49Å; F135-F234 AromaticContact CE1-CG 3.49Å; F135-F234 HydrophobicContact CE1-CG 3.49Å; F135-F234 VanDerWaalsContact CE1-CG 3.49Å; F135-F234 AromaticContact CE2-CD2 3.98Å; F135-F234 HydrophobicContact CE2-CD2 3.98Å; F135-F234 AromaticContact CE2-CE2 3.99Å; F135-F234 HydrophobicContact CE2-CE2 3.99Å; F135-F234 HydrophobicContact CE2-CG 4.42Å; F135-F234 HydrophobicContact CE2-CZ 4.4Å; F135-F234 HydrophobicContact CG-CD2 4.45Å; F135-F234 HydrophobicContact CZ-CB 4.28Å; F135-F234 AromaticContact CZ-CD1 3.85Å; F135-F234 HydrophobicContact CZ-CD1 3.85Å; F135-F234 AromaticContact CZ-CD2 3.69Å; F135-F234 HydrophobicContact CZ-CD2 3.69Å; F135-F234 HydrophobicContact CZ-CE1 4.05Å; F135-F234 AromaticContact CZ-CE2 3.92Å; F135-F234 HydrophobicContact CZ-CE2 3.92Å; F135-F234 AromaticContact CZ-CG 3.68Å; F135-F234 HydrophobicContact CZ-CG 3.68Å; F135-F234 HydrophobicContact CZ-CZ 4.09Å; F216-F234 HydrophobicContact CD2-CE1 4.37Å; F216-F234 HydrophobicContact CE2-CE1 4.13Å; F216-F234 HydrophobicContact CE2-CZ 4.17Å; F234-M236 HydrophobicContact CD2-CG 4.44Å; F234-M236 HydrophobicContact CE1-CG 4.46Å; F234-M236 HydrophobicContact CE2-CG 3.75Å; F234-M236 HydrophobicContact CE2-SD 3.84Å; F234-M236 HydrophobicContact CZ-CG 3.76Å; F234-M236 HydrophobicContact CZ-SD 3.98Å; F234-I282 HydrophobicContact CD1-CB 4.21Å; F234-I282 HydrophobicContact CD1-CG2 3.88Å; F234-I282 HydrophobicContact CE1-CB 4.36Å; F234-I282 HydrophobicContact CE1-CG2 3.64Å; F234-I282 HydrophobicContact CZ-CG2 4.16Å; F234-A336 CarbonylContact O-C 3.55Å; F234-A336 WeakPolarHBondContact O-CA 3.44Å; F234-L337 PolarHBondContact N-O 3.11Å; F234-L337 PolarHBondContact O-N 2.78Å; F234-F353 HydrophobicContact CB-CD1 3.91Å; F234-F353 HydrophobicContact CB-CE1 4.03Å; F234-F353 HydrophobicContact CD1-CB 4.41Å; F234-F353 HydrophobicContact CD1-CD1 4.26Å; F234-L355 HydrophobicContact CE1-CB 4.23Å; F234-L355 HydrophobicContact CZ-CB 4.43Å; F234-L355 HydrophobicContact CZ-CD2 4.49Å
235T98.7Very high96.2Very high0 Ų029.7 Ų29.70%015%0.153CC..EExtended strand (participates in β ladder)trans-109.2142.317753.40000111.2A132 N133 Q134 W162 M233 F298 L307 A335 A336A132-T235 WeakPolarHBondContact O-CB 3.3Å; A132-T235 PolarHBondContact O-OG1 3.48Å; N133-T235 WeakPolarHBondContact CA-O 3.36Å; Q134-T235 PolarHBondContact N-O 2.94Å; Q134-T235 PolarHBondContact N-OG1 2.99Å; Q134-T235 PolarHBondContact O-N 3.45Å; Q134-T235 PolarHBondContact O-OG1 3.1Å; W162-T235 HydrophobicContact CH2-CG2 3.97Å; M233-T235 HydrophobicContact CE-CG2 3.87Å; M233-T235 HydrophobicContact CG-CG2 4.12Å; M233-T235 HydrophobicContact SD-CG2 4.04Å; T235-F298 HydrophobicContact CG2-CE1 4.44Å; T235-F298 HydrophobicContact CG2-CZ 4.33Å; T235-L307 HydrophobicContact CG2-CD2 4.25Å; T235-A335 WeakPolarHBondContact CA-O 3.22Å; T235-A336 HydrophobicContact CG2-CB 3.78Å
236M98.4Very high96.1Very high0 Ų027.9 Ų27.90%014%0.139CC..EExtended strand (participates in β ladder)trans-141.6136.4173.6-77.1-62.9-91.600111.6W118 N133 F234 L269 I282 A334 A335 L355W118-M236 HydrophobicContact CH2-CE 3.77Å; W118-M236 HydrophobicContact CZ3-CE 4.32Å; N133-M236 HydrophobicContact CB-SD 3.51Å; N133-M236 VanDerWaalsContact CB-SD 3.51Å; N133-M236 PolarHBondContact ND2-SD 2.98Å; N133-M236 WeakPolarHBondContact OD1-CA 3.35Å; F234-M236 HydrophobicContact CD2-CG 4.44Å; F234-M236 HydrophobicContact CE1-CG 4.46Å; F234-M236 HydrophobicContact CE2-CG 3.75Å; F234-M236 HydrophobicContact CE2-SD 3.84Å; F234-M236 HydrophobicContact CZ-CG 3.76Å; F234-M236 HydrophobicContact CZ-SD 3.98Å; M236-L269 HydrophobicContact CB-CD2 4.34Å; M236-L269 WeakPolarHBondContact O-CD2 3.29Å; M236-I282 HydrophobicContact CB-CG2 3.94Å; M236-I282 HydrophobicContact CG-CG2 3.49Å; M236-I282 VanDerWaalsContact CG-CG2 3.49Å; M236-A334 CarbonylContact O-C 3.52Å; M236-A334 WeakPolarHBondContact O-CA 3.26Å; M236-A334 WeakPolarHBondContact O-CB 3.15Å; M236-A335 PolarHBondContact N-O 2.86Å; M236-A335 PolarHBondContact O-N 2.7Å; M236-L355 HydrophobicContact CE-CD1 3.81Å; M236-L355 HydrophobicContact CE-CD2 3.74Å; M236-L355 HydrophobicContact CE-CG 4.46Å
237V97.9Very high96Very high5 Ų526.9 Ų26.93%0.0314%0.143CC..EExtended strand (participates in β ladder)trans-74.2141.8166.3176.50000109.4V130 A132 N133 G239 P300 A334V130-V237 HydrophobicContact CG1-CB 3.92Å; V130-V237 HydrophobicContact CG1-CG2 3.66Å; A132-V237 HydrophobicContact CB-CG2 3.69Å; N133-V237 PolarHBondContact OD1-N 2.85Å; V237-G239 VanDerWaalsContact C-N 3.27Å; V237-G239 PolarHBondContact O-N 3.1Å; V237-P300 HydrophobicContact CG2-CB 4.43Å; V237-P300 HydrophobicContact CG2-CG 4.36Å; V237-A334 HydrophobicContact CG2-CB 4.22Å
238N97.9Very high95.9Very high2 Ų225.2 Ų25.21%0.01113%0.13CC..SBendtrans-71.285.9167.2-173.9-29.9000109.1W251 N252 L269 H270 H271 V333N238-W251 PolarHBondContact ND2-O 3.34Å; N238-N252 PolarHBondContact ND2-OD1 3.41Å; N238-L269 HydrophobicContact CB-CB 3.87Å; N238-L269 HydrophobicContact CB-CD2 3.92Å; N238-L269 HydrophobicContact CB-CG 4.48Å; N238-H270 PolarHBondContact ND2-N 3.04Å; N238-H270 PolarHBondContact ND2-O 3.4Å; N238-H270 PolarHBondContact OD1-O 3.42Å; N238-H271 PolarHBondContact O-ND1 2.99Å; N238-H271 WeakPolarHBondContact OD1-CA 3.3Å; N238-H271 WeakPolarHBondContact OD1-CB 3.36Å; N238-H271 PolarHBondContact OD1-N 2.77Å; N238-H271 PolarHBondContact OD1-ND1 2.78Å; N238-V333 HydrophobicContact CB-CG1 3.68Å; N238-V333 WeakPolarHBondContact CB-O 3.4Å; N238-V333 PolarHBondContact N-O 2.67Å
239G94.5Very high95.8Very high0 Ų026.5 Ų26.50%015%0.145CC..SBendtrans143.8-171-178.500000113.3V237 D245 Y278V237-G239 VanDerWaalsContact C-N 3.27Å; V237-G239 PolarHBondContact O-N 3.1Å; G239-D245 WeakPolarHBondContact CA-OD1 3.31Å; G239-Y278 WeakPolarHBondContact CA-OH 3.49Å
240S92.8Very high95.8Very high8 Ų823.5 Ų23.56%0.05613%0.129CC..  trans-115.77.9-173.460.40000113.2W118 H126 V130 H242 D245W118-S240 VanDerWaalsContact CD1-O 3.32Å; W118-S240 PolarHBondContact NE1-O 3.16Å; H126-S240 PolarHBondContact CD2-OG 3.24Å; V130-S240 WeakPolarHBondContact CG2-O 3.35Å; S240-H242 VanDerWaalsContact C-N 3.28Å; S240-D245 PolarHBondContact N-OD1 3.2Å; S240-D245 VanDerWaalsContact N-OD1 3.14Å
241G88.3Confident95.8Very high4 Ų426.6 Ų26.64%0.04114%0.141CC..SBendtrans87.3-4.4-173.400000113.9K128 D245K128-G241 WeakPolarHBondContact CD-O 3.49Å; K128-G241 PolarHBondContact NZ-O 3.19Å; G241-D245 WeakPolarHBondContact CA-OD2 3.29Å; G241-D245 PolarHBondContact N-OD1 2.95Å; G241-D245 PolarHBondContact N-OD2 3.31Å
242H90.9Very high95.8Very high57 Ų5726.4 Ų26.426%0.26414%0.14SC..SBendtrans-70.5177.9-179-164-120.3000112H126 S240 D244 D245H126-H242 AromaticContact CD2-CG 3.96Å; H126-H242 AromaticContact CE1-CD2 3.3Å; H126-H242 PolarHBondContact CE1-CD2 2.86Å; H126-H242 AromaticContact CE1-CE1 3.73Å; H126-H242 AromaticContact CE1-CG 3.55Å; H126-H242 AromaticContact CE1-ND1 3.82Å; H126-H242 AromaticContact CE1-NE2 3.5Å; H126-H242 PolarHBondContact CE1-NE2 3.09Å; H126-H242 AromaticContact CG-CD2 3.85Å; H126-H242 AromaticContact ND1-CD2 3.32Å; H126-H242 PolarHBondContact ND1-CD2 2.84Å; H126-H242 VanDerWaalsContact ND1-CD2 3.32Å; H126-H242 AromaticContact ND1-CG 3.87Å; H126-H242 AromaticContact ND1-NE2 3.8Å; H126-H242 AromaticContact NE2-CD2 3.83Å; H126-H242 AromaticContact NE2-CG 3.6Å; H126-H242 AromaticContact NE2-ND1 3.87Å; S240-H242 VanDerWaalsContact C-N 3.28Å; H242-D244 IonicContact CE1-OD2 3.18Å; H242-D244 PolarHBondContact CE1-OD2 3.02Å; H242-D244 IonicContact CG-OD2 3.84Å; H242-D244 IonicContact ND1-OD2 2.67Å; H242-D244 PolarHBondContact ND1-OD2 2.77Å; H242-D244 PolarHBondContact O-N 2.98Å; H242-D245 PolarHBondContact N-OD1 3.08Å
243K90.8Very high95.8Very high157 Ų15729 Ų2968%0.68315%0.151SC*.SBendtrans-66.3-26.5177.973.5-167.2178.5-177.20111.7D245 K246K243-D245 VanDerWaalsContact C-N 3.3Å; K243-D245 PolarHBondContact O-N 3.11Å; K243-K246 PolarHBondContact O-N 3.45Å
244D93.2Very high95.8Very high52 Ų5230.8 Ų30.828%0.27816%0.163SC..G310 helixtrans-72.9-22.4-174.8-53.6-39.3000112.2H242 K246 S247 H250 T273H242-D244 IonicContact CE1-OD2 3.18Å; H242-D244 PolarHBondContact CE1-OD2 3.02Å; H242-D244 IonicContact CG-OD2 3.84Å; H242-D244 IonicContact ND1-OD2 2.67Å; H242-D244 PolarHBondContact ND1-OD2 2.77Å; H242-D244 PolarHBondContact O-N 2.98Å; D244-K246 PolarHBondContact O-N 3.35Å; D244-S247 WeakPolarHBondContact O-CB 3.05Å; D244-S247 PolarHBondContact O-N 2.53Å; D244-S247 PolarHBondContact O-OG 3.42Å; D244-H250 PolarHBondContact O-NE2 2.83Å; D244-T273 HydrophobicContact CB-CG2 3.95Å
245D94.1Very high95.7Very high0 Ų032 Ų320%017%0.168CC..G310 helixtrans-50.2-18.6166.8-59.57.2000114.4G239 S240 G241 H242 K243 H271 E331 K332G239-D245 WeakPolarHBondContact CA-OD1 3.31Å; S240-D245 PolarHBondContact N-OD1 3.2Å; S240-D245 VanDerWaalsContact N-OD1 3.14Å; G241-D245 WeakPolarHBondContact CA-OD2 3.29Å; G241-D245 PolarHBondContact N-OD1 2.95Å; G241-D245 PolarHBondContact N-OD2 3.31Å; H242-D245 PolarHBondContact N-OD1 3.08Å; K243-D245 VanDerWaalsContact C-N 3.3Å; K243-D245 PolarHBondContact O-N 3.11Å; D245-H271 IonicContact OD1-CE1 3.2Å; D245-E331 VanDerWaalsContact O-O 3.04Å; D245-K332 HydrophobicContact CB-CD 4.14Å; D245-K332 HydrophobicContact CB-CG 4.27Å; D245-K332 IonicContact OD2-NZ 2.73Å; D245-K332 PolarHBondContact OD2-NZ 2.82Å
246K95.3Very high95.7Very high100 Ų10036.9 Ų36.944%0.43519%0.191SC..G310 helixtrans-111.69.3-179.2-63.3-176.2-178.4-179.20113.1K243 D244 G248 G330 E331 K332K243-K246 PolarHBondContact O-N 3.45Å; D244-K246 PolarHBondContact O-N 3.35Å; K246-G248 PolarHBondContact O-N 3.19Å; K246-G330 PolarHBondContact O-N 3.23Å; K246-E331 WeakPolarHBondContact CA-O 3.48Å; K246-K332 HydrophobicContact CG-CG 3.95Å
247S95.3Very high95.7Very high55 Ų5538.9 Ų38.939%0.38520%0.202SC..SBendtrans-68-21.5-179.859.20000112.5D244 H250D244-S247 WeakPolarHBondContact O-CB 3.05Å; D244-S247 PolarHBondContact O-N 2.53Å; D244-S247 PolarHBondContact O-OG 3.42Å; S247-H250 PolarHBondContact OG-CE1 3.35Å; S247-H250 VanDerWaalsContact OG-CE1 3.32Å; S247-H250 PolarHBondContact OG-NE2 3.3Å; S247-H250 VanDerWaalsContact OG-NE2 3.14Å
248G95.7Very high95.6Very high15 Ų1545.1 Ų45.116%0.15523%0.231CC..SBendtrans85.7164.8-173.100000111.1K246 H250 T327K246-G248 PolarHBondContact O-N 3.19Å; G248-H250 VanDerWaalsContact C-N 3.32Å; G248-H250 PolarHBondContact O-N 3.43Å; G248-T327 CarbonylContact C-O 3.51Å; G248-T327 WeakPolarHBondContact CA-O 3.37Å
249G97.3Very high95.6Very high33 Ų3349.9 Ų49.934%0.3425%0.251SS..  trans87.2-10.7-179.500000115T327G249-T327 PolarHBondContact N-O 3.04Å; G249-T327 PolarHBondContact N-OG1 3.12Å
250H98.1Very high95.6Very high2 Ų256.4 Ų56.41%0.00929%0.286CS..  trans-70.9145.4173.7-43.7-57.1000111.2D244 S247 G248 H270 H271 C272 P326 T327D244-H250 PolarHBondContact O-NE2 2.83Å; S247-H250 PolarHBondContact OG-CE1 3.35Å; S247-H250 VanDerWaalsContact OG-CE1 3.32Å; S247-H250 PolarHBondContact OG-NE2 3.3Å; S247-H250 VanDerWaalsContact OG-NE2 3.14Å; G248-H250 VanDerWaalsContact C-N 3.32Å; G248-H250 PolarHBondContact O-N 3.43Å; H250-H270 WeakPolarHBondContact CA-O 3.3Å; H250-H271 AromaticContact CE1-CE1 3.58Å; H250-H271 AromaticContact CE1-ND1 3.67Å; H250-H271 AromaticContact ND1-CE1 3.98Å; H250-H271 AromaticContact ND1-CG 3.99Å; H250-H271 AromaticContact ND1-ND1 3.6Å; H250-H271 AromaticContact NE2-CE1 3.9Å; H250-C272 PolarHBondContact ND1-N 3.17Å; H250-C272 VanDerWaalsContact ND1-N 3.16Å; H250-P326 WeakPolarHBondContact O-CA 3.28Å; H250-T327 PolarHBondContact N-OG1 3.37Å; H250-T327 VanDerWaalsContact N-OG1 3.12Å; H250-T327 WeakPolarHBondContact O-CG2 3.35Å; H250-T327 PolarHBondContact O-N 3.08Å; H250-T327 PolarHBondContact O-OG1 2.88Å
251W98.4Very high95.7Very high65 Ų6559.1 Ų59.125%0.24632%0.315CS..EExtended strand (participates in β ladder)trans-153.3163.9-178.961.5-77.5000110.7N238 E253 H270N238-W251 PolarHBondContact ND2-O 3.34Å; W251-E253 HydrophobicContact CE3-CB 4.35Å; W251-E253 HydrophobicContact CH2-CG 4.17Å; W251-E253 WeakPolarHBondContact CH2-OE2 3.46Å; W251-E253 HydrophobicContact CZ3-CB 3.74Å; W251-E253 VanDerWaalsContact CZ3-CD 3.41Å; W251-E253 HydrophobicContact CZ3-CG 3.7Å; W251-E253 VanDerWaalsContact CZ3-OE2 3.24Å; W251-E253 WeakPolarHBondContact CZ3-OE2 3.24Å; W251-H270 HydrophobicContact CD2-CB 4.18Å; W251-H270 AromaticContact CD2-CD2 3.58Å; W251-H270 AromaticContact CE2-CD2 3.4Å; W251-H270 AromaticContact CE2-CG 3.57Å; W251-H270 AromaticContact CE3-CD2 3.64Å; W251-H270 HydrophobicContact CG-CB 4.28Å; W251-H270 AromaticContact CH2-CD2 3.35Å; W251-H270 WeakPolarHBondContact CH2-CD2 3.48Å; W251-H270 AromaticContact CH2-NE2 3.37Å; W251-H270 WeakPolarHBondContact CH2-NE2 3.49Å; W251-H270 HydrophobicContact CZ2-CB 4.16Å; W251-H270 AromaticContact CZ2-CD2 3.28Å; W251-H270 WeakPolarHBondContact CZ2-CD2 3.06Å; W251-H270 AromaticContact CZ2-CG 3.55Å; W251-H270 AromaticContact CZ2-NE2 3.65Å; W251-H270 AromaticContact CZ3-CD2 3.55Å; W251-H270 AromaticContact CZ3-NE2 3.75Å; W251-H270 PolarHBondContact N-O 3.35Å; W251-H270 AromaticContact NE1-CG 3.9Å; W251-H270 WeakPolarHBondContact O-CB 3.34Å; W251-H270 PolarHBondContact O-N 3.23Å
252N98.7Very high96.1Very high0 Ų061.8 Ų61.80%033%0.326CS..EExtended strand (participates in β ladder)trans-126.7154.4-179.7-59.8-6.8000110.9N238 V267 L268 T296 S323 S324 A334N238-N252 PolarHBondContact ND2-OD1 3.41Å; N252-V267 HydrophobicContact CB-CG1 4.03Å; N252-L268 CarbonylContact C-O 3.55Å; N252-L268 WeakPolarHBondContact CA-O 3.42Å; N252-L268 WeakPolarHBondContact CB-O 3.49Å; N252-T296 HydrophobicContact CB-CG2 4.14Å; N252-T296 VanDerWaalsContact CB-O 3.22Å; N252-T296 WeakPolarHBondContact CB-O 3.36Å; N252-T296 PolarHBondContact ND2-O 3.41Å; N252-S323 CarbonylContact O-C 3.53Å; N252-S323 WeakPolarHBondContact O-CA 3.37Å; N252-S324 PolarHBondContact N-OG 3.21Å; N252-S324 PolarHBondContact O-N 3.08Å; N252-S324 PolarHBondContact O-OG 3.09Å; N252-A334 PolarHBondContact ND2-O 3.25Å
253E98.2Very high96.4Very high53 Ų5359.8 Ų59.825%0.24832%0.32CS..EExtended strand (participates in β ladder)trans-145.3146.9170.662.3-177.5178.700113.3W251 V267 L268 H270 S323W251-E253 HydrophobicContact CE3-CB 4.35Å; W251-E253 HydrophobicContact CH2-CG 4.17Å; W251-E253 WeakPolarHBondContact CH2-OE2 3.46Å; W251-E253 HydrophobicContact CZ3-CB 3.74Å; W251-E253 VanDerWaalsContact CZ3-CD 3.41Å; W251-E253 HydrophobicContact CZ3-CG 3.7Å; W251-E253 VanDerWaalsContact CZ3-OE2 3.24Å; W251-E253 WeakPolarHBondContact CZ3-OE2 3.24Å; E253-V267 CarbonylContact O-C 3.17Å; E253-V267 WeakPolarHBondContact O-CA 3.28Å; E253-V267 WeakPolarHBondContact O-CG1 3.38Å; E253-L268 HydrophobicContact CG-CB 4.01Å; E253-L268 HydrophobicContact CG-CD1 4.17Å; E253-L268 HydrophobicContact CG-CG 4.39Å; E253-L268 PolarHBondContact N-O 3.41Å; E253-L268 PolarHBondContact O-N 3.29Å; E253-H270 IonicContact OE1-CE1 4Å; E253-H270 IonicContact OE1-NE2 2.69Å; E253-H270 PolarHBondContact OE1-NE2 2.98Å; E253-S323 WeakPolarHBondContact CB-OG 3.38Å; E253-S323 PolarHBondContact OE2-OG 3.36Å
254P98.2Very high96.7Very high38 Ų3852.3 Ų52.325%0.24729%0.287CS..EExtended strand (participates in β ladder)trans-72.7150.5169.533.6-34.2000110.1G266 H294 G322P254-G266 WeakPolarHBondContact CA-O 3.42Å; P254-H294 WeakPolarHBondContact CB-NE2 3.42Å; P254-G322 VanDerWaalsContact CD-O 3.3Å; P254-G322 WeakPolarHBondContact CD-O 3.32Å
255F97.9Very high96.9Very high25 Ų2550.4 Ų50.411%0.1128%0.278CS..EExtended strand (participates in β ladder)trans-136.9158.3171.680.5-80.8000110.9L257 V264 S265 G266 L268 C281 A283 P387F255-L257 HydrophobicContact CD2-CB 4.44Å; F255-L257 HydrophobicContact CE2-CB 4.47Å; F255-V264 HydrophobicContact CE2-CG1 4.25Å; F255-V264 HydrophobicContact CZ-CG1 4.19Å; F255-S265 WeakPolarHBondContact O-CA 3.31Å; F255-G266 VanDerWaalsContact CD1-C 3.45Å; F255-G266 WeakPolarHBondContact CD1-O 3.47Å; F255-G266 VanDerWaalsContact CE1-C 3.48Å; F255-G266 VanDerWaalsContact CE1-CA 3.47Å; F255-G266 PolarHBondContact N-O 2.92Å; F255-G266 PolarHBondContact O-N 3.1Å; F255-G266 VanDerWaalsContact O-N 3.15Å; F255-L268 HydrophobicContact CB-CD1 4.3Å; F255-L268 HydrophobicContact CB-CG 4.27Å; F255-L268 HydrophobicContact CD1-CD2 3.65Å; F255-L268 HydrophobicContact CD1-CG 3.74Å; F255-L268 HydrophobicContact CE1-CD2 3.89Å; F255-L268 HydrophobicContact CE1-CG 4.46Å; F255-L268 HydrophobicContact CG-CD2 4.24Å; F255-L268 HydrophobicContact CG-CG 4.2Å; F255-C281 WeakPolarHBondContact CE1-SG 3.33Å; F255-A283 HydrophobicContact CE1-CB 4.25Å; F255-A283 HydrophobicContact CZ-CB 3.78Å; F255-P387 HydrophobicContact CD2-CB 3.8Å; F255-P387 HydrophobicContact CD2-CG 4.09Å; F255-P387 HydrophobicContact CE2-CB 3.87Å; F255-P387 HydrophobicContact CE2-CG 4.45Å; F255-P387 HydrophobicContact CG-CG 4.4Å
256H97.5Very high97.1Very high104 Ų10450.5 Ų50.548%0.48128%0.279SS..EExtended strand (participates in β ladder)trans-138.2132.2169.8174.385.3000107.7S265 E286H256-S265 PolarHBondContact ND1-OG 3.01Å; H256-E286 IonicContact CE1-OE1 2.97Å; H256-E286 IonicContact CE1-OE2 3.29Å; H256-E286 PolarHBondContact CE1-OE2 2.99Å; H256-E286 IonicContact ND1-OE1 3.96Å; H256-E286 PolarHBondContact ND1-OE1 2.86Å; H256-E286 IonicContact ND1-OE2 2.72Å
257L98.2Very high97.3Very high41 Ų4145.7 Ų45.722%0.21526%0.258CS..EExtended strand (participates in β ladder)trans-133.5115.9176.8176.862.7000109.3F255 A263 V264 P387 H391F255-L257 HydrophobicContact CD2-CB 4.44Å; F255-L257 HydrophobicContact CE2-CB 4.47Å; L257-A263 WeakPolarHBondContact O-CA 3.37Å; L257-V264 PolarHBondContact N-O 2.92Å; L257-V264 PolarHBondContact O-N 2.83Å; L257-P387 HydrophobicContact CD2-CB 4.04Å; L257-P387 WeakPolarHBondContact CD2-O 3.49Å; L257-H391 HydrophobicContact CD2-CB 3.83Å
258E97.4Very high97.5Very high137 Ų13743.6 Ų43.664%0.6424%0.242SC*.EExtended strand (participates in β ladder)trans-103122.1168.1-171.1-179.2157.800109.2E262 A263E258-E262 WeakPolarHBondContact CA-O 3.5Å; E258-A263 HydrophobicContact CB-CB 4.4Å; E258-A263 HydrophobicContact CG-CB 4.39Å
259K96.5Very high97.6Very high101 Ų10142.9 Ų42.944%0.43924%0.235SC..EExtended strand (participates in β ladder)trans-150138.6178.9-178.5-174.7174.1-172.30109.7G261 E262 H391K259-G261 PolarHBondContact O-N 3.07Å; K259-E262 PolarHBondContact N-O 3.32Å; K259-E262 PolarHBondContact O-N 3.22Å; K259-H391 PolarHBondContact O-CE1 3.34Å; K259-H391 PolarHBondContact O-NE2 3.41Å
260D94.8Very high97.7Very high138 Ų13842.5 Ų42.574%0.73822%0.224SC*.THydrogen-bonded Turntrans55.132.3178.9-54.6-39.8000113.9E262D260-E262 VanDerWaalsContact C-N 3.26Å; D260-E262 PolarHBondContact O-N 3.38Å
261G94.4Very high97.7Very high64 Ų6442.7 Ų42.766%0.6623%0.225SC*.THydrogen-bonded Turntrans77.37.9-178.300000114.7K259K259-G261 PolarHBondContact O-N 3.07Å
262E96.4Very high97.6Very high60 Ų6042.1 Ų42.128%0.2823%0.231SC..EExtended strand (participates in β ladder)trans-120.2131.4179.9-62.9-63.8173.500110.3E258 K259 D260 R285 H391 T395E258-E262 WeakPolarHBondContact CA-O 3.5Å; K259-E262 PolarHBondContact N-O 3.32Å; K259-E262 PolarHBondContact O-N 3.22Å; D260-E262 VanDerWaalsContact C-N 3.26Å; D260-E262 PolarHBondContact O-N 3.38Å; E262-R285 IonicContact OE1-CZ 3.8Å; E262-R285 IonicContact OE1-NH2 2.72Å; E262-R285 PolarHBondContact OE1-NH2 2.85Å; E262-R285 IonicContact OE2-CZ 3.1Å; E262-R285 IonicContact OE2-NE 2.78Å; E262-R285 PolarHBondContact OE2-NE 3.34Å; E262-R285 IonicContact OE2-NH2 2.71Å; E262-R285 PolarHBondContact OE2-NH2 2.76Å; E262-H391 PolarHBondContact O-NE2 3.18Å; E262-T395 HydrophobicContact CB-CG2 3.94Å; E262-T395 HydrophobicContact CG-CG2 4.1Å
263A97.3Very high97.3Very high15 Ų1543.6 Ų43.612%0.12424%0.239CC..EExtended strand (participates in β ladder)trans-108.1138.2-18000000111.5L257 E258 E286L257-A263 WeakPolarHBondContact O-CA 3.37Å; E258-A263 HydrophobicContact CB-CB 4.4Å; E258-A263 HydrophobicContact CG-CB 4.39Å; A263-E286 HydrophobicContact CB-CB 4Å; A263-E286 HydrophobicContact CB-CG 4.38Å; A263-E286 PolarHBondContact O-N 3.29Å
264V98Very high97Very high0 Ų046.4 Ų46.40%027%0.272CS..EExtended strand (participates in β ladder)trans-130.1135.5174.6172.10000108.9F255 L257 A283 A284 R285 H391 L394F255-V264 HydrophobicContact CE2-CG1 4.25Å; F255-V264 HydrophobicContact CZ-CG1 4.19Å; L257-V264 PolarHBondContact N-O 2.92Å; L257-V264 PolarHBondContact O-N 2.83Å; V264-A283 HydrophobicContact CG1-CB 3.72Å; V264-A284 WeakPolarHBondContact CA-O 3.33Å; V264-R285 HydrophobicContact CG2-CB 4.49Å; V264-H391 HydrophobicContact CG2-CB 4.31Å; V264-L394 HydrophobicContact CB-CD1 4.41Å; V264-L394 HydrophobicContact CG1-CD1 3.67Å; V264-L394 HydrophobicContact CG2-CB 4.33Å; V264-L394 HydrophobicContact CG2-CD1 3.79Å
265S98Very high96.7Very high13 Ų1348.6 Ų48.69%0.09129%0.285CS..EExtended strand (participates in β ladder)trans-132153.6178.2-73.20000111.1F255 H256 A283 A284 E286F255-S265 WeakPolarHBondContact O-CA 3.31Å; H256-S265 PolarHBondContact ND1-OG 3.01Å; S265-A283 WeakPolarHBondContact O-CA 3.26Å; S265-A284 PolarHBondContact N-O 2.93Å; S265-A284 PolarHBondContact O-N 3.03Å; S265-E286 VanDerWaalsContact CB-OE1 3.24Å; S265-E286 WeakPolarHBondContact CB-OE1 3.39Å; S265-E286 PolarHBondContact OG-OE1 2.99Å
266G98.2Very high96.6Very high1 Ų148.1 Ų48.11%0.0128%0.283CS..EExtended strand (participates in β ladder)trans176-157.6-176.500000113.7P254 F255 I282P254-G266 WeakPolarHBondContact CA-O 3.42Å; F255-G266 VanDerWaalsContact CD1-C 3.45Å; F255-G266 WeakPolarHBondContact CD1-O 3.47Å; F255-G266 VanDerWaalsContact CE1-C 3.48Å; F255-G266 VanDerWaalsContact CE1-CA 3.47Å; F255-G266 PolarHBondContact N-O 2.92Å; F255-G266 PolarHBondContact O-N 3.1Å; F255-G266 VanDerWaalsContact O-N 3.15Å; G266-I282 CarbonylContact C-O 3.6Å; G266-I282 WeakPolarHBondContact CA-O 3.33Å
267V98.8Very high96.5Very high0 Ų046.6 Ų46.60%028%0.283CS..EExtended strand (participates in β ladder)trans-128.9130.2178.8-171.50000109.8N252 E253 C281 I282 H294 A335N252-V267 HydrophobicContact CB-CG1 4.03Å; E253-V267 CarbonylContact O-C 3.17Å; E253-V267 WeakPolarHBondContact O-CA 3.28Å; E253-V267 WeakPolarHBondContact O-CG1 3.38Å; V267-C281 WeakPolarHBondContact O-CA 3.48Å; V267-I282 HydrophobicContact CB-CG1 4.19Å; V267-I282 PolarHBondContact N-O 3.07Å; V267-I282 PolarHBondContact O-N 3.26Å; V267-I282 VanDerWaalsContact O-N 3.11Å; V267-H294 HydrophobicContact CG2-CB 3.78Å; V267-A335 HydrophobicContact CB-CB 3.93Å; V267-A335 HydrophobicContact CG1-CB 3.59Å; V267-A335 HydrophobicContact CG2-CB 4.3Å
268L98.9Very high96.5Very high11 Ų1145.3 Ų45.36%0.05828%0.275CS..EExtended strand (participates in β ladder)trans-88.5135.9168.7-54.1-178000109N252 E253 F255 T279 L280 C281 P387N252-L268 CarbonylContact C-O 3.55Å; N252-L268 WeakPolarHBondContact CA-O 3.42Å; N252-L268 WeakPolarHBondContact CB-O 3.49Å; E253-L268 HydrophobicContact CG-CB 4.01Å; E253-L268 HydrophobicContact CG-CD1 4.17Å; E253-L268 HydrophobicContact CG-CG 4.39Å; E253-L268 PolarHBondContact N-O 3.41Å; E253-L268 PolarHBondContact O-N 3.29Å; F255-L268 HydrophobicContact CB-CD1 4.3Å; F255-L268 HydrophobicContact CB-CG 4.27Å; F255-L268 HydrophobicContact CD1-CD2 3.65Å; F255-L268 HydrophobicContact CD1-CG 3.74Å; F255-L268 HydrophobicContact CE1-CD2 3.89Å; F255-L268 HydrophobicContact CE1-CG 4.46Å; F255-L268 HydrophobicContact CG-CD2 4.24Å; F255-L268 HydrophobicContact CG-CG 4.2Å; L268-T279 HydrophobicContact CB-CG2 3.99Å; L268-T279 HydrophobicContact CD2-CG2 4.4Å; L268-L280 CarbonylContact C-O 3.5Å; L268-L280 WeakPolarHBondContact CA-O 3.48Å; L268-C281 HydrophobicContact CD2-CB 3.8Å; L268-P387 HydrophobicContact CD1-CG 4.03Å; L268-P387 HydrophobicContact CD2-CG 4.11Å
269L98.8Very high96.6Very high0 Ų039.4 Ų39.40%025%0.248CC..EExtended strand (participates in β ladder)trans-120.299.4177.9-52.887.7000108.1M236 N238 H271 T279 L280 I282 A335M236-L269 HydrophobicContact CB-CD2 4.34Å; M236-L269 WeakPolarHBondContact O-CD2 3.29Å; N238-L269 HydrophobicContact CB-CB 3.87Å; N238-L269 HydrophobicContact CB-CD2 3.92Å; N238-L269 HydrophobicContact CB-CG 4.48Å; L269-H271 PolarHBondContact O-N 3.06Å; L269-T279 WeakPolarHBondContact O-CA 3.34Å; L269-L280 HydrophobicContact CB-CB 4.18Å; L269-L280 HydrophobicContact CD1-CB 4.16Å; L269-L280 PolarHBondContact N-O 3.36Å; L269-L280 PolarHBondContact O-N 3.36Å; L269-I282 HydrophobicContact CD1-CG1 4.42Å; L269-A335 HydrophobicContact CD1-CB 4.42Å; L269-A335 HydrophobicContact CD2-CB 3.95Å; L269-A335 HydrophobicContact CG-CB 4.18Å
270H98.5Very high96.7Very high25 Ų2534.6 Ų34.612%0.11623%0.228CC..EExtended strand (participates in β ladder)trans-82.3107.1-176.1-57.7-78000110.3N238 H250 W251 E253 C272 T279N238-H270 PolarHBondContact ND2-N 3.04Å; N238-H270 PolarHBondContact ND2-O 3.4Å; N238-H270 PolarHBondContact OD1-O 3.42Å; H250-H270 WeakPolarHBondContact CA-O 3.3Å; W251-H270 HydrophobicContact CD2-CB 4.18Å; W251-H270 AromaticContact CD2-CD2 3.58Å; W251-H270 AromaticContact CE2-CD2 3.4Å; W251-H270 AromaticContact CE2-CG 3.57Å; W251-H270 AromaticContact CE3-CD2 3.64Å; W251-H270 HydrophobicContact CG-CB 4.28Å; W251-H270 AromaticContact CH2-CD2 3.35Å; W251-H270 WeakPolarHBondContact CH2-CD2 3.48Å; W251-H270 AromaticContact CH2-NE2 3.37Å; W251-H270 WeakPolarHBondContact CH2-NE2 3.49Å; W251-H270 HydrophobicContact CZ2-CB 4.16Å; W251-H270 AromaticContact CZ2-CD2 3.28Å; W251-H270 WeakPolarHBondContact CZ2-CD2 3.06Å; W251-H270 AromaticContact CZ2-CG 3.55Å; W251-H270 AromaticContact CZ2-NE2 3.65Å; W251-H270 AromaticContact CZ3-CD2 3.55Å; W251-H270 AromaticContact CZ3-NE2 3.75Å; W251-H270 PolarHBondContact N-O 3.35Å; W251-H270 AromaticContact NE1-CG 3.9Å; W251-H270 WeakPolarHBondContact O-CB 3.34Å; W251-H270 PolarHBondContact O-N 3.23Å; E253-H270 IonicContact OE1-CE1 4Å; E253-H270 IonicContact OE1-NE2 2.69Å; E253-H270 PolarHBondContact OE1-NE2 2.98Å; H270-C272 PolarHBondContact O-N 3.11Å; H270-T279 PolarHBondContact ND1-OG1 3.49Å; H270-T279 VanDerWaalsContact ND1-OG1 3.11Å
271H98Very high96.9Very high5 Ų528 Ų282%0.02319%0.193CC..EExtended strand (participates in β ladder)trans-93.684.3179.4-163.875.7000110.2N238 D245 H250 L269 T273 Y278N238-H271 PolarHBondContact O-ND1 2.99Å; N238-H271 WeakPolarHBondContact OD1-CA 3.3Å; N238-H271 WeakPolarHBondContact OD1-CB 3.36Å; N238-H271 PolarHBondContact OD1-N 2.77Å; N238-H271 PolarHBondContact OD1-ND1 2.78Å; D245-H271 IonicContact OD1-CE1 3.2Å; H250-H271 AromaticContact CE1-CE1 3.58Å; H250-H271 AromaticContact CE1-ND1 3.67Å; H250-H271 AromaticContact ND1-CE1 3.98Å; H250-H271 AromaticContact ND1-CG 3.99Å; H250-H271 AromaticContact ND1-ND1 3.6Å; H250-H271 AromaticContact NE2-CE1 3.9Å; L269-H271 PolarHBondContact O-N 3.06Å; H271-T273 VanDerWaalsContact CD2-CG2 3.49Å; H271-T273 WeakPolarHBondContact CD2-CG2 3.5Å; H271-T273 WeakPolarHBondContact NE2-CG2 3.14Å; H271-T273 PolarHBondContact O-N 3.37Å; H271-Y278 WeakPolarHBondContact CA-O 3.24Å; H271-Y278 HydrophobicContact CB-CD1 4.13Å; H271-Y278 HydrophobicContact CB-CD2 4.06Å; H271-Y278 HydrophobicContact CB-CE1 3.86Å; H271-Y278 HydrophobicContact CB-CE2 3.77Å; H271-Y278 HydrophobicContact CB-CG 4.23Å; H271-Y278 WeakPolarHBondContact CB-O 3.24Å; H271-Y278 AromaticContact CD2-CD1 3.96Å; H271-Y278 AromaticContact CD2-CE1 3.17Å; H271-Y278 WeakPolarHBondContact CD2-CE1 3.28Å; H271-Y278 AromaticContact CD2-CZ 3.43Å; H271-Y278 VanDerWaalsContact CD2-CZ 3.43Å; H271-Y278 PolarHBondContact CD2-OH 3.19Å; H271-Y278 AromaticContact CG-CE1 3.7Å; H271-Y278 AromaticContact CG-CZ 3.55Å; H271-Y278 PolarHBondContact N-O 3.32Å; H271-Y278 PolarHBondContact O-N 3.21Å
272C96.5Very high97.1Very high54 Ų5425 Ų2537%0.36516%0.161SC..  trans-77.385.7-176.6-52.80000113H250 H270H250-C272 PolarHBondContact ND1-N 3.17Å; H250-C272 VanDerWaalsContact ND1-N 3.16Å; H270-C272 PolarHBondContact O-N 3.11Å
273T93.6Very high97.2Very high30 Ų3022.1 Ų22.118%0.18415%0.148CC..  trans-97.3159.2169.948.40000111.9D244 H271 T275 N276 P277D244-T273 HydrophobicContact CB-CG2 3.95Å; H271-T273 VanDerWaalsContact CD2-CG2 3.49Å; H271-T273 WeakPolarHBondContact CD2-CG2 3.5Å; H271-T273 WeakPolarHBondContact NE2-CG2 3.14Å; H271-T273 PolarHBondContact O-N 3.37Å; T273-T275 VanDerWaalsContact C-N 3.29Å; T273-T275 WeakPolarHBondContact CB-O 3.32Å; T273-T275 PolarHBondContact O-N 2.96Å; T273-T275 PolarHBondContact OG1-O 3.31Å; T273-N276 PolarHBondContact OG1-O 3Å; T273-P277 WeakPolarHBondContact OG1-CA 3.33Å
274A90.6Very high97.2Very high112 Ų11221.4 Ų21.493%0.92614%0.142SC*.SBendtrans-67.2-31.5177.500000112.9
275T92.1Very high97.1Very high85 Ų8523.4 Ų23.452%0.52115%0.149SC..SBendtrans-120.6135.3177.8-510000108.1T273 T363T273-T275 VanDerWaalsContact C-N 3.29Å; T273-T275 WeakPolarHBondContact CB-O 3.32Å; T273-T275 PolarHBondContact O-N 2.96Å; T273-T275 PolarHBondContact OG1-O 3.31Å; T275-T363 WeakPolarHBondContact CG2-OG1 3.5Å
276N95.8Very high97Very high14 Ų1426.3 Ų26.38%0.07516%0.162CC..SBendtrans46.759.1178.4-57-20.4000113.1N121 T273 M359 I362 T363N121-N276 WeakPolarHBondContact OD1-CB 3.39Å; N121-N276 PolarHBondContact OD1-ND2 3.19Å; T273-N276 PolarHBondContact OG1-O 3Å; N276-M359 HydrophobicContact CB-CE 4.17Å; N276-M359 HydrophobicContact CB-CG 4.41Å; N276-M359 HydrophobicContact CB-SD 3.88Å; N276-M359 WeakPolarHBondContact O-CE 3.43Å; N276-I362 WeakPolarHBondContact OD1-CA 3.42Å; N276-T363 PolarHBondContact ND2-O 3.34Å; N276-T363 PolarHBondContact OD1-N 2.9Å; N276-T363 PolarHBondContact OD1-OG1 2.76Å
277P97Very high96.7Very high73 Ų7329.1 Ų29.147%0.47417%0.174SC..  trans-62.1151.7172.230.2-35.5000110.2T273T273-P277 WeakPolarHBondContact OG1-CA 3.33Å
278Y97.8Very high96.3Very high13 Ų1334.8 Ų34.85%0.05122%0.221CC..EExtended strand (participates in β ladder)trans-147.6159.9-179.963.4-86.7000112.4L120 G239 H271 L280 D358 M359L120-Y278 HydrophobicContact CD1-CD2 4.09Å; L120-Y278 HydrophobicContact CD1-CE1 4.23Å; L120-Y278 HydrophobicContact CD1-CE2 3.56Å; G239-Y278 WeakPolarHBondContact CA-OH 3.49Å; H271-Y278 WeakPolarHBondContact CA-O 3.24Å; H271-Y278 HydrophobicContact CB-CD1 4.13Å; H271-Y278 HydrophobicContact CB-CD2 4.06Å; H271-Y278 HydrophobicContact CB-CE1 3.86Å; H271-Y278 HydrophobicContact CB-CE2 3.77Å; H271-Y278 HydrophobicContact CB-CG 4.23Å; H271-Y278 WeakPolarHBondContact CB-O 3.24Å; H271-Y278 AromaticContact CD2-CD1 3.96Å; H271-Y278 AromaticContact CD2-CE1 3.17Å; H271-Y278 WeakPolarHBondContact CD2-CE1 3.28Å; H271-Y278 AromaticContact CD2-CZ 3.43Å; H271-Y278 VanDerWaalsContact CD2-CZ 3.43Å; H271-Y278 PolarHBondContact CD2-OH 3.19Å; H271-Y278 AromaticContact CG-CE1 3.7Å; H271-Y278 AromaticContact CG-CZ 3.55Å; H271-Y278 PolarHBondContact N-O 3.32Å; H271-Y278 PolarHBondContact O-N 3.21Å; Y278-L280 HydrophobicContact CD2-CD2 3.76Å; Y278-L280 HydrophobicContact CD2-CG 3.93Å; Y278-L280 HydrophobicContact CE2-CD1 4.09Å; Y278-L280 HydrophobicContact CE2-CD2 3.6Å; Y278-L280 HydrophobicContact CE2-CG 3.62Å; Y278-D358 CarbonylContact C-O 3.31Å; Y278-D358 WeakPolarHBondContact CA-O 3.34Å; Y278-D358 VanDerWaalsContact CB-O 3.29Å; Y278-D358 WeakPolarHBondContact CB-O 3.47Å; Y278-M359 HydrophobicContact CD1-CE 3.39Å; Y278-M359 HydrophobicContact CE1-CE 4.19Å; Y278-M359 HydrophobicContact CG-CE 3.81Å
279T98.6Very high96Very high13 Ų1338.7 Ų38.78%0.0824%0.242CC..EExtended strand (participates in β ladder)trans-116.5113.6175.4-59.80000109.5L268 L269 H270 W357 D358 S386L268-T279 HydrophobicContact CB-CG2 3.99Å; L268-T279 HydrophobicContact CD2-CG2 4.4Å; L269-T279 WeakPolarHBondContact O-CA 3.34Å; H270-T279 PolarHBondContact ND1-OG1 3.49Å; H270-T279 VanDerWaalsContact ND1-OG1 3.11Å; T279-W357 WeakPolarHBondContact O-CA 3.34Å; T279-D358 PolarHBondContact N-O 2.83Å; T279-D358 PolarHBondContact O-N 2.85Å; T279-S386 PolarHBondContact O-OG 2.77Å
280L98.6Very high95.7Very high1 Ų140 Ų401%0.00525%0.247CC..EExtended strand (participates in β ladder)trans-78.7155.5167.2-55.4176.6000109.8L120 L268 L269 Y278 A356 W357L120-L280 HydrophobicContact CD1-CD2 4.33Å; L268-L280 CarbonylContact C-O 3.5Å; L268-L280 WeakPolarHBondContact CA-O 3.48Å; L269-L280 HydrophobicContact CB-CB 4.18Å; L269-L280 HydrophobicContact CD1-CB 4.16Å; L269-L280 PolarHBondContact N-O 3.36Å; L269-L280 PolarHBondContact O-N 3.36Å; Y278-L280 HydrophobicContact CD2-CD2 3.76Å; Y278-L280 HydrophobicContact CD2-CG 3.93Å; Y278-L280 HydrophobicContact CE2-CD1 4.09Å; Y278-L280 HydrophobicContact CE2-CD2 3.6Å; Y278-L280 HydrophobicContact CE2-CG 3.62Å; L280-A356 CarbonylContact C-O 3.48Å; L280-A356 WeakPolarHBondContact CA-O 3.48Å; L280-W357 HydrophobicContact CD2-CB 3.46Å; L280-W357 VanDerWaalsContact CD2-CB 3.46Å; L280-W357 HydrophobicContact CD2-CG 4.48Å
281C98.5Very high95.6Very high0 Ų042 Ų420%026%0.256CS..EExtended strand (participates in β ladder)trans-141.3125.6175.7171.80000110F255 V267 L268 L355 A356F255-C281 WeakPolarHBondContact CE1-SG 3.33Å; V267-C281 WeakPolarHBondContact O-CA 3.48Å; L268-C281 HydrophobicContact CD2-CB 3.8Å; C281-L355 WeakPolarHBondContact O-CA 3.14Å; C281-A356 HydrophobicContact CB-CB 4.38Å; C281-A356 PolarHBondContact N-O 3.11Å; C281-A356 PolarHBondContact O-N 2.84Å
282I98.9Very high95.6Very high0 Ų043.2 Ų43.20%026%0.264CS..EExtended strand (participates in β ladder)trans-103.2127.4162.358.2178.8000107.8F234 M236 G266 V267 L269 A335 L337 C354 L355F234-I282 HydrophobicContact CD1-CB 4.21Å; F234-I282 HydrophobicContact CD1-CG2 3.88Å; F234-I282 HydrophobicContact CE1-CB 4.36Å; F234-I282 HydrophobicContact CE1-CG2 3.64Å; F234-I282 HydrophobicContact CZ-CG2 4.16Å; M236-I282 HydrophobicContact CB-CG2 3.94Å; M236-I282 HydrophobicContact CG-CG2 3.49Å; M236-I282 VanDerWaalsContact CG-CG2 3.49Å; G266-I282 CarbonylContact C-O 3.6Å; G266-I282 WeakPolarHBondContact CA-O 3.33Å; V267-I282 HydrophobicContact CB-CG1 4.19Å; V267-I282 PolarHBondContact N-O 3.07Å; V267-I282 PolarHBondContact O-N 3.26Å; V267-I282 VanDerWaalsContact O-N 3.11Å; L269-I282 HydrophobicContact CD1-CG1 4.42Å; I282-A335 HydrophobicContact CD1-CB 4.07Å; I282-L337 HydrophobicContact CB-CD2 4.47Å; I282-L337 HydrophobicContact CD1-CB 3.8Å; I282-L337 HydrophobicContact CG1-CB 4.13Å; I282-C354 WeakPolarHBondContact CA-O 3.2Å; I282-L355 HydrophobicContact CG2-CD1 4.22Å
283A98.8Very high95.7Very high0 Ų041 Ų410%025%0.25CC..EExtended strand (participates in β ladder)trans-143.1158.5-173.500000112.4F255 V264 S265 F353 C354 L394F255-A283 HydrophobicContact CE1-CB 4.25Å; F255-A283 HydrophobicContact CZ-CB 3.78Å; V264-A283 HydrophobicContact CG1-CB 3.72Å; S265-A283 WeakPolarHBondContact O-CA 3.26Å; A283-F353 CarbonylContact O-C 3.58Å; A283-F353 VanDerWaalsContact O-CA 3.29Å; A283-F353 WeakPolarHBondContact O-CA 3.47Å; A283-C354 HydrophobicContact CB-CB 4.44Å; A283-C354 PolarHBondContact N-O 2.94Å; A283-C354 PolarHBondContact O-N 3Å; A283-L394 HydrophobicContact CB-CD1 4.32Å
284A98.5Very high95.9Very high0 Ų041.9 Ų41.90%025%0.252CS..EExtended strand (participates in β ladder)trans-141.215317300000109.9V264 S265 V292 L337 V339 E352V264-A284 WeakPolarHBondContact CA-O 3.33Å; S265-A284 PolarHBondContact N-O 2.93Å; S265-A284 PolarHBondContact O-N 3.03Å; A284-V292 HydrophobicContact CB-CG1 4.26Å; A284-V292 HydrophobicContact CB-CG2 4.21Å; A284-L337 HydrophobicContact CB-CD2 3.92Å; A284-V339 HydrophobicContact CB-CG2 3.33Å; A284-E352 WeakPolarHBondContact CB-O 3.38Å
285R95.4Very high96.3Very high41 Ų4138.2 Ų38.216%0.15522%0.215CC..EExtended strand (participates in β ladder)trans-80.4133.7176.4-172.1172.8174.6-179.9-3.7110E262 V264 Q287 L394E262-R285 IonicContact OE1-CZ 3.8Å; E262-R285 IonicContact OE1-NH2 2.72Å; E262-R285 PolarHBondContact OE1-NH2 2.85Å; E262-R285 IonicContact OE2-CZ 3.1Å; E262-R285 IonicContact OE2-NE 2.78Å; E262-R285 PolarHBondContact OE2-NE 3.34Å; E262-R285 IonicContact OE2-NH2 2.71Å; E262-R285 PolarHBondContact OE2-NH2 2.76Å; V264-R285 HydrophobicContact CG2-CB 4.49Å; R285-Q287 HydrophobicContact CG-CG 4.27Å; R285-L394 HydrophobicContact CB-CD1 4.42Å
286E94.8Very high96.5Very high75 Ų7534.3 Ų34.335%0.3519%0.191SC..EExtended strand (participates in β ladder)trans-80.5130.3172.3-63.5-169.8178.500109.7H256 A263 S265 V292H256-E286 IonicContact CE1-OE1 2.97Å; H256-E286 IonicContact CE1-OE2 3.29Å; H256-E286 PolarHBondContact CE1-OE2 2.99Å; H256-E286 IonicContact ND1-OE1 3.96Å; H256-E286 PolarHBondContact ND1-OE1 2.86Å; H256-E286 IonicContact ND1-OE2 2.72Å; A263-E286 HydrophobicContact CB-CB 4Å; A263-E286 HydrophobicContact CB-CG 4.38Å; A263-E286 PolarHBondContact O-N 3.29Å; S265-E286 VanDerWaalsContact CB-OE1 3.24Å; S265-E286 WeakPolarHBondContact CB-OE1 3.39Å; S265-E286 PolarHBondContact OG-OE1 2.99Å; E286-V292 HydrophobicContact CG-CG2 4.24Å
287Q93.2Very high96.6Very high59 Ų5935.2 Ų35.228%0.27620%0.201SC..  trans-141152.5179.1-63.6176.3-29.400108.5R285 D289 R290R285-Q287 HydrophobicContact CG-CG 4.27Å; Q287-D289 PolarHBondContact O-N 2.7Å; Q287-D289 VanDerWaalsContact O-N 3.12Å; Q287-R290 HydrophobicContact CB-CB 4.05Å; Q287-R290 HydrophobicContact CB-CG 3.76Å; Q287-R290 HydrophobicContact CG-CG 4.45Å; Q287-R290 PolarHBondContact O-N 3.27Å
288A89.4Confident96.6Very high120 Ų12033 Ų3399%0.99218%0.183SC*.THydrogen-bonded Turntrans-61.6-25-173.600000114.3
289D92.2Very high96.4Very high93 Ų9335.3 Ų35.350%0.49720%0.202SC..THydrogen-bonded Turntrans-104.716.8178.672.3-35.7000112.8Q287Q287-D289 PolarHBondContact O-N 2.7Å; Q287-D289 VanDerWaalsContact O-N 3.12Å
290R93.9Very high96.1Very high27 Ų2735.4 Ų35.410%0.10220%0.203CC..  trans-127.7147178.5-61.7-64.2-179.7-93.2-8.2110Q287 V339 S340 N349 S350 L351Q287-R290 HydrophobicContact CB-CB 4.05Å; Q287-R290 HydrophobicContact CB-CG 3.76Å; Q287-R290 HydrophobicContact CG-CG 4.45Å; Q287-R290 PolarHBondContact O-N 3.27Å; R290-V339 HydrophobicContact CB-CG1 4.37Å; R290-S340 WeakPolarHBondContact CA-O 3.47Å; R290-N349 PolarHBondContact NH1-ND2 3.46Å; R290-N349 VanDerWaalsContact NH1-ND2 3.1Å; R290-N349 PolarHBondContact NH2-ND2 2.85Å; R290-N349 PolarHBondContact NH2-OD1 2.74Å; R290-S350 PolarHBondContact NE-O 3.38Å; R290-S350 VanDerWaalsContact NE-O 3.11Å; R290-S350 PolarHBondContact NH2-O 3.33Å; R290-L351 VanDerWaalsContact CD-CD2 3.43Å; R290-L351 VanDerWaalsContact NE-CD2 3.33Å
291E95.7Very high95.7Very high66 Ų6640.7 Ų40.731%0.30823%0.226SC..EExtended strand (participates in β ladder)trans-124.9121.1173.8157.8-173.1-97.100108.9R316 V339 S340E291-R316 VanDerWaalsContact CD-CD 3.43Å; E291-R316 VanDerWaalsContact CD-CZ 3.48Å; E291-R316 WeakPolarHBondContact OE1-CD 3.44Å; E291-R316 IonicContact OE1-CZ 3.79Å; E291-R316 IonicContact OE1-NE 3.38Å; E291-R316 PolarHBondContact OE1-NE 3.23Å; E291-R316 IonicContact OE1-NH1 2.52Å; E291-R316 PolarHBondContact OE1-NH1 3.4Å; E291-R316 IonicContact OE1-NH2 3.26Å; E291-R316 VanDerWaalsContact OE2-CD 3.31Å; E291-R316 WeakPolarHBondContact OE2-CD 3.28Å; E291-R316 VanDerWaalsContact OE2-CG 3.3Å; E291-R316 WeakPolarHBondContact OE2-CG 3.13Å; E291-R316 IonicContact OE2-NE 3.83Å; E291-V339 CarbonylContact O-C 3.49Å; E291-V339 WeakPolarHBondContact O-CA 3.37Å; E291-S340 VanDerWaalsContact CB-OG 3.27Å; E291-S340 WeakPolarHBondContact CB-OG 3.32Å; E291-S340 PolarHBondContact N-O 2.91Å; E291-S340 VanDerWaalsContact N-O 3.16Å; E291-S340 PolarHBondContact O-N 2.88Å; E291-S340 PolarHBondContact O-OG 2.84Å; E291-S340 PolarHBondContact OE2-OG 3.14Å
292V97.8Very high95.2Very high31 Ų3142.9 Ų42.919%0.18825%0.248CC..EExtended strand (participates in β ladder)trans-102.5127.1-179.6-175.70000107.7A284 E286 L337 V339A284-V292 HydrophobicContact CB-CG1 4.26Å; A284-V292 HydrophobicContact CB-CG2 4.21Å; E286-V292 HydrophobicContact CG-CG2 4.24Å; V292-L337 HydrophobicContact CG1-CD1 3.61Å; V292-V339 HydrophobicContact CG2-CG1 4.44Å; V292-V339 HydrophobicContact CG2-CG2 4.4Å
293S98.2Very high94.9Very high8 Ų846.4 Ų46.46%0.05627%0.27CS..EExtended strand (participates in β ladder)trans-137.5158.7175.659.20000109.6L317 L337 A338S293-L317 WeakPolarHBondContact CB-O 3.43Å; S293-L317 PolarHBondContact OG-N 3.49Å; S293-L337 WeakPolarHBondContact O-CD1 3.49Å; S293-A338 PolarHBondContact N-O 3.47Å; S293-A338 PolarHBondContact O-N 3.4Å; S293-A338 VanDerWaalsContact O-O 3.11Å
294H98.3Very high94.6Very high49 Ų4947.3 Ų47.323%0.22728%0.276CS..EExtended strand (participates in β ladder)trans-144.1169.7-175.361.3-89.7000110.9P254 V267 T296 L317 S319 A336 L337P254-H294 WeakPolarHBondContact CB-NE2 3.42Å; V267-H294 HydrophobicContact CG2-CB 3.78Å; H294-T296 PolarHBondContact CD2-OG1 2.86Å; H294-L317 VanDerWaalsContact O-CB 3.31Å; H294-L317 WeakPolarHBondContact O-CB 3.28Å; H294-S319 PolarHBondContact CD2-OG 3.33Å; H294-S319 VanDerWaalsContact O-CB 3.28Å; H294-S319 WeakPolarHBondContact O-CB 3.46Å; H294-A336 CarbonylContact C-O 3.58Å; H294-A336 WeakPolarHBondContact CA-O 3.22Å; H294-A336 WeakPolarHBondContact CB-O 3.24Å; H294-L337 HydrophobicContact CB-CD1 4.25Å
295Q98.2Very high94.4Very high34 Ų3449.5 Ų49.516%0.15929%0.291CS..EExtended strand (participates in β ladder)trans-127.1110.5160.617563.9-65.700106.8A297 F298 L307 D318 S319 P320 A335 A336Q295-A297 VanDerWaalsContact C-N 3.28Å; Q295-A297 PolarHBondContact O-N 2.93Å; Q295-F298 HydrophobicContact CG-CB 4.39Å; Q295-F298 HydrophobicContact CG-CD1 4.49Å; Q295-L307 HydrophobicContact CB-CD1 3.8Å; Q295-L307 HydrophobicContact CG-CD1 4.02Å; Q295-D318 PolarHBondContact NE2-O 2.96Å; Q295-D318 PolarHBondContact OE1-O 2.63Å; Q295-S319 PolarHBondContact OE1-OG 3.1Å; Q295-P320 VanDerWaalsContact OE1-CD 3.29Å; Q295-A335 WeakPolarHBondContact O-CA 3.13Å; Q295-A336 HydrophobicContact CB-CB 4.16Å; Q295-A336 PolarHBondContact N-O 2.67Å; Q295-A336 PolarHBondContact O-N 3.22Å
296T98.1Very high94.4Very high4 Ų450.3 Ų50.33%0.02531%0.312CS..EExtended strand (participates in β ladder)trans-58.5-42.9-172.3-61.30000111.2N252 H294 S319N252-T296 HydrophobicContact CB-CG2 4.14Å; N252-T296 VanDerWaalsContact CB-O 3.22Å; N252-T296 WeakPolarHBondContact CB-O 3.36Å; N252-T296 PolarHBondContact ND2-O 3.41Å; H294-T296 PolarHBondContact CD2-OG1 2.86Å; T296-S319 PolarHBondContact N-OG 3.44Å; T296-S319 PolarHBondContact OG1-OG 2.87Å
297A97.2Very high94.5Very high33 Ų3347.2 Ų47.227%0.27330%0.298SS..EExtended strand (participates in β ladder)trans-148.1131.6-177.800000112.2Q295 V333 A334Q295-A297 VanDerWaalsContact C-N 3.28Å; Q295-A297 PolarHBondContact O-N 2.93Å; A297-V333 HydrophobicContact CB-CG2 3.66Å; A297-A334 CarbonylContact C-O 3.58Å; A297-A334 VanDerWaalsContact CA-O 3.3Å; A297-A334 WeakPolarHBondContact CA-O 3.42Å
298F96Very high94.7Very high25 Ų2545.5 Ų45.511%0.1129%0.289CS..EExtended strand (participates in β ladder)trans-139.8155.7162.974-82000110.4W162 T235 Q295 P300 L307 A334 A336W162-F298 HydrophobicContact CZ2-CE2 4.47Å; T235-F298 HydrophobicContact CG2-CE1 4.44Å; T235-F298 HydrophobicContact CG2-CZ 4.33Å; Q295-F298 HydrophobicContact CG-CB 4.39Å; Q295-F298 HydrophobicContact CG-CD1 4.49Å; F298-P300 HydrophobicContact CE2-CB 4.39Å; F298-P300 WeakPolarHBondContact O-CD 3.19Å; F298-L307 HydrophobicContact CD1-CD2 3.97Å; F298-L307 HydrophobicContact CD2-CD2 4.31Å; F298-L307 HydrophobicContact CE1-CD2 3.75Å; F298-L307 HydrophobicContact CE2-CD2 4.12Å; F298-L307 HydrophobicContact CG-CD2 4.24Å; F298-L307 HydrophobicContact CZ-CD2 3.83Å; F298-A334 HydrophobicContact CD1-CB 4.01Å; F298-A334 WeakPolarHBondContact CD1-O 3.28Å; F298-A334 HydrophobicContact CD2-CB 4.46Å; F298-A334 HydrophobicContact CE1-CB 3.51Å; F298-A334 HydrophobicContact CE2-CB 4.01Å; F298-A334 HydrophobicContact CG-CB 4.46Å; F298-A334 HydrophobicContact CZ-CB 3.51Å; F298-A334 PolarHBondContact N-O 3.39Å; F298-A334 PolarHBondContact O-N 2.89Å; F298-A336 HydrophobicContact CE1-CB 4.28Å
299S94.2Very high95Very high62 Ų6242.7 Ų42.743%0.43426%0.262SS..  trans-81124.1172.1178.10000109.3K301 C304S299-K301 PolarHBondContact O-N 3.38Å; S299-K301 VanDerWaalsContact O-N 3.14Å; S299-K301 PolarHBondContact OG-N 2.88Å; S299-C304 PolarHBondContact O-SG 3.27Å
300P93Very high95.3Very high15 Ų1539.5 Ų39.510%0.09725%0.245CC..  trans-7710.4175.132.8-35.7000112.8A132 V237 F298 K332 A334A132-P300 HydrophobicContact CB-CB 3.96Å; V237-P300 HydrophobicContact CG2-CB 4.43Å; V237-P300 HydrophobicContact CG2-CG 4.36Å; F298-P300 HydrophobicContact CE2-CB 4.39Å; F298-P300 WeakPolarHBondContact O-CD 3.19Å; P300-K332 HydrophobicContact CG-CB 3.96Å; P300-A334 HydrophobicContact CB-CB 4.3Å; P300-A334 HydrophobicContact CG-CB 4.3Å
301K89.1Confident95.5Very high113 Ų11338.2 Ų38.249%0.49124%0.24SC..SBendtrans-89.8145.1175.3-64.6-179.2-177.3171.50110.3S299 G330S299-K301 PolarHBondContact O-N 3.38Å; S299-K301 VanDerWaalsContact O-N 3.14Å; S299-K301 PolarHBondContact OG-N 2.88Å; K301-G330 PolarHBondContact NZ-O 3.44Å
302G89.3Confident95.5Very high46 Ų4638.2 Ų38.247%0.47424%0.242SC..SBendtrans85.4-151.117600000112.9L159L159-G302 PolarHBondContact N-O 2.98Å
303T90.7Very high95.5Very high74 Ų7441.5 Ų41.545%0.45426%0.262SS..  trans-82.5-26.7-174.964.60000113.4L159 Q160 G161 S305L159-T303 CarbonylContact C-O 3.44Å; L159-T303 VanDerWaalsContact C-O 3.32Å; L159-T303 WeakPolarHBondContact CA-O 3.22Å; Q160-T303 HydrophobicContact CB-CG2 4.46Å; G161-T303 WeakPolarHBondContact CA-O 3.46Å; G161-T303 PolarHBondContact N-O 3.42Å; T303-S305 WeakPolarHBondContact CB-OG 3.41Å; T303-S305 PolarHBondContact O-N 3.12Å; T303-S305 PolarHBondContact OG1-N 3.15Å; T303-S305 PolarHBondContact OG1-OG 3.1Å
304C93.6Very high95.4Very high18 Ų1844.1 Ų44.112%0.12228%0.275CS..  trans51.433.8-173.9-58.60000113.7L159 W162 S299 G306 W308L159-C304 HydrophobicContact CD2-CB 3.62Å; L159-C304 WeakPolarHBondContact CD2-SG 3.38Å; W162-C304 HydrophobicContact CZ2-CB 4.35Å; W162-C304 PolarHBondContact NE1-O 2.93Å; W162-C304 VanDerWaalsContact NE1-O 3.08Å; S299-C304 PolarHBondContact O-SG 3.27Å; C304-G306 PolarHBondContact O-N 3.11Å; C304-W308 PolarHBondContact O-N 3.43Å
305S94.3Very high95.3Very high46 Ų4641.8 Ų41.832%0.32227%0.265SS..Hα-helixtrans-62.6-28.7179.5-54.30000113.1T303 W308 S309T303-S305 WeakPolarHBondContact CB-OG 3.41Å; T303-S305 PolarHBondContact O-N 3.12Å; T303-S305 PolarHBondContact OG1-N 3.15Å; T303-S305 PolarHBondContact OG1-OG 3.1Å; S305-W308 PolarHBondContact O-N 3.05Å; S305-S309 WeakPolarHBondContact O-CB 3.27Å; S305-S309 PolarHBondContact O-N 3.13Å; S305-S309 PolarHBondContact O-OG 2.72Å; S305-S309 VanDerWaalsContact O-OG 3.09Å
306G95.1Very high95.2Very high58 Ų5844.8 Ų44.860%0.59828%0.275SS*.Hα-helixtrans-58.3-55.7178.400000112.4C304 W308 S309 D310C304-G306 PolarHBondContact O-N 3.11Å; G306-W308 VanDerWaalsContact C-N 3.26Å; G306-W308 PolarHBondContact O-N 2.9Å; G306-S309 PolarHBondContact O-N 2.95Å; G306-D310 WeakPolarHBondContact O-CB 3.27Å; G306-D310 PolarHBondContact O-N 3.33Å
307L96.7Very high95.2Very high11 Ų1145 Ų456%0.05828%0.276CS..Hα-helixtrans-60.3-36.6177.6-175.869.2000112.5W162 M233 T235 Q295 F298 L311 L317 A336W162-L307 HydrophobicContact CZ2-CD2 4.02Å; M233-L307 HydrophobicContact CE-CD2 4.46Å; M233-L307 HydrophobicContact SD-CD1 4.4Å; M233-L307 HydrophobicContact SD-CD2 4.12Å; M233-L307 HydrophobicContact SD-CG 4.12Å; T235-L307 HydrophobicContact CG2-CD2 4.25Å; Q295-L307 HydrophobicContact CB-CD1 3.8Å; Q295-L307 HydrophobicContact CG-CD1 4.02Å; F298-L307 HydrophobicContact CD1-CD2 3.97Å; F298-L307 HydrophobicContact CD2-CD2 4.31Å; F298-L307 HydrophobicContact CE1-CD2 3.75Å; F298-L307 HydrophobicContact CE2-CD2 4.12Å; F298-L307 HydrophobicContact CG-CD2 4.24Å; F298-L307 HydrophobicContact CZ-CD2 3.83Å; L307-L311 PolarHBondContact O-N 3.43Å; L307-L317 HydrophobicContact CD1-CD1 4.39Å; L307-L317 HydrophobicContact CD1-CD2 3.7Å; L307-A336 HydrophobicContact CD1-CB 4.08Å; L307-A336 HydrophobicContact CD2-CB 4.02Å
308W97.1Very high95.1Very high22 Ų2248.7 Ų48.78%0.08329%0.291CS..Hα-helixtrans-68.3-44.9179-175.9-95.9000112.7T136 Q148 V150 G161 W162 N163 C304 S305 G306 D310 I312T136-W308 HydrophobicContact CG2-CE3 4.4Å; T136-W308 HydrophobicContact CG2-CH2 3.98Å; T136-W308 HydrophobicContact CG2-CZ3 3.51Å; Q148-W308 HydrophobicContact CB-CH2 4.28Å; Q148-W308 HydrophobicContact CB-CZ2 3.94Å; Q148-W308 HydrophobicContact CG-CH2 3.62Å; Q148-W308 HydrophobicContact CG-CZ2 3.65Å; Q148-W308 HydrophobicContact CG-CZ3 4.18Å; Q148-W308 VanDerWaalsContact NE2-CE3 3.31Å; Q148-W308 PolarHBondContact NE2-O 2.84Å; Q148-W308 VanDerWaalsContact NE2-O 3.16Å; V150-W308 HydrophobicContact CG2-CH2 4.05Å; V150-W308 HydrophobicContact CG2-CZ3 3.62Å; G161-W308 VanDerWaalsContact O-CD1 3.22Å; W162-W308 HydrophobicContact CB-CD2 3.93Å; W162-W308 HydrophobicContact CB-CE3 3.44Å; W162-W308 VanDerWaalsContact CB-CE3 3.44Å; W162-W308 HydrophobicContact CB-CH2 4.31Å; W162-W308 HydrophobicContact CB-CZ3 3.64Å; W162-W308 AromaticContact CD1-CD2 3.95Å; W162-W308 AromaticContact CD1-CE3 3.67Å; W162-W308 AromaticContact CD1-CG 3.94Å; W162-W308 HydrophobicContact CD2-CE3 4.02Å; W162-W308 HydrophobicContact CD2-CZ3 4.46Å; W162-W308 HydrophobicContact CG-CB 4.45Å; W162-W308 HydrophobicContact CG-CD2 4.03Å; W162-W308 AromaticContact CG-CE3 3.42Å; W162-W308 HydrophobicContact CG-CE3 3.42Å; W162-W308 VanDerWaalsContact CG-CE3 3.42Å; W162-W308 HydrophobicContact CG-CG 4.48Å; W162-W308 HydrophobicContact CG-CZ3 4Å; N163-W308 HydrophobicContact CB-CH2 3.71Å; N163-W308 HydrophobicContact CB-CZ2 3.41Å; N163-W308 VanDerWaalsContact CB-CZ2 3.41Å; N163-W308 VanDerWaalsContact N-CH2 3.29Å; C304-W308 PolarHBondContact O-N 3.43Å; S305-W308 PolarHBondContact O-N 3.05Å; G306-W308 VanDerWaalsContact C-N 3.26Å; G306-W308 PolarHBondContact O-N 2.9Å; W308-D310 VanDerWaalsContact C-N 3.35Å; W308-I312 WeakPolarHBondContact O-CG1 3.39Å; W308-I312 PolarHBondContact O-N 3.32Å
309S97.1Very high95Very high61 Ų6149.2 Ų49.243%0.42730%0.298SS..Hα-helixtrans-69.7-32.5178.7-660000112.7S305 G306 I312 T313S305-S309 WeakPolarHBondContact O-CB 3.27Å; S305-S309 PolarHBondContact O-N 3.13Å; S305-S309 PolarHBondContact O-OG 2.72Å; S305-S309 VanDerWaalsContact O-OG 3.09Å; G306-S309 PolarHBondContact O-N 2.95Å; S309-I312 PolarHBondContact O-N 2.99Å; S309-T313 PolarHBondContact O-N 3.39Å; S309-T313 VanDerWaalsContact O-N 3.1Å; S309-T313 PolarHBondContact O-OG1 2.72Å
310D97.5Very high94.7Very high27 Ų2750.7 Ų50.714%0.14431%0.306CS..Hα-helixtrans-56.2-58173.7-170.525.7000110.3G306 W308 I312 T313 L317 D318G306-D310 WeakPolarHBondContact O-CB 3.27Å; G306-D310 PolarHBondContact O-N 3.33Å; W308-D310 VanDerWaalsContact C-N 3.35Å; D310-I312 VanDerWaalsContact C-N 3.26Å; D310-I312 PolarHBondContact O-N 3.33Å; D310-I312 VanDerWaalsContact O-N 3.16Å; D310-T313 VanDerWaalsContact O-CB 3.32Å; D310-T313 WeakPolarHBondContact O-CB 3.44Å; D310-T313 PolarHBondContact O-N 3.14Å; D310-L317 WeakPolarHBondContact OD2-CA 3.4Å; D310-D318 PolarHBondContact OD2-N 2.83Å
311L97.6Very high94.5Very high0 Ų057 Ų570%034%0.344CS..Hα-helixtrans-58.7-33.7176.7-168.170.3000113.6T136 C138 M233 L307 T313 G315 R316 L317 A338T136-L311 HydrophobicContact CG2-CD2 4.27Å; C138-L311 HydrophobicContact CB-CD2 4.12Å; C138-L311 HydrophobicContact CB-CG 4.12Å; M233-L311 HydrophobicContact CB-CD2 3.86Å; M233-L311 HydrophobicContact CE-CD2 4.33Å; M233-L311 HydrophobicContact SD-CD2 4.23Å; L307-L311 PolarHBondContact O-N 3.43Å; L311-T313 VanDerWaalsContact C-N 3.28Å; L311-T313 PolarHBondContact O-N 2.9Å; L311-G315 WeakPolarHBondContact O-CA 3.22Å; L311-G315 PolarHBondContact O-N 3.21Å; L311-R316 WeakPolarHBondContact CA-O 3.44Å; L311-L317 HydrophobicContact CB-CD2 4.12Å; L311-L317 HydrophobicContact CD1-CD2 4.17Å; L311-L317 HydrophobicContact CD1-CG 4.5Å; L311-A338 HydrophobicContact CD1-CB 4.09Å
312I96.9Very high94.7Very high65 Ų6553.4 Ų53.433%0.33334%0.339SS..Hα-helixtrans-65.2-34.1175.5-76.8177.6000111.5R140 T145 Q148 W308 S309 D310R140-I312 PolarHBondContact NH1-O 2.76Å; T145-I312 WeakPolarHBondContact CB-O 3.49Å; T145-I312 HydrophobicContact CG2-CG1 4.49Å; T145-I312 PolarHBondContact OG1-O 2.87Å; Q148-I312 HydrophobicContact CB-CG1 4.42Å; Q148-I312 VanDerWaalsContact OE1-CG1 3.24Å; W308-I312 WeakPolarHBondContact O-CG1 3.39Å; W308-I312 PolarHBondContact O-N 3.32Å; S309-I312 PolarHBondContact O-N 2.99Å; D310-I312 VanDerWaalsContact C-N 3.26Å; D310-I312 PolarHBondContact O-N 3.33Å; D310-I312 VanDerWaalsContact O-N 3.16Å
313T96.9Very high95.1Very high101 Ų10154.4 Ų54.462%0.6234%0.339SS*.Hα-helixtrans-65.4-54.1-168.8-63.20000110.3R140 S309 D310 L311R140-T313 PolarHBondContact NH1-O 3.05Å; R140-T313 PolarHBondContact NH2-O 2.79Å; S309-T313 PolarHBondContact O-N 3.39Å; S309-T313 VanDerWaalsContact O-N 3.1Å; S309-T313 PolarHBondContact O-OG1 2.72Å; D310-T313 VanDerWaalsContact O-CB 3.32Å; D310-T313 WeakPolarHBondContact O-CB 3.44Å; D310-T313 PolarHBondContact O-N 3.14Å; L311-T313 VanDerWaalsContact C-N 3.28Å; L311-T313 PolarHBondContact O-N 2.9Å
314D96.2Very high95.4Very high62 Ų6251.7 Ų51.733%0.33232%0.323SS..Hα-helixtrans-133.3-2.9-174.166.4-1.4000114.7R140 R316R140-D314 VanDerWaalsContact NE-C 3.34Å; R140-D314 PolarHBondContact NE-O 2.84Å; D314-R316 VanDerWaalsContact C-N 3.32Å; D314-R316 WeakPolarHBondContact OD1-CA 3.29Å; D314-R316 WeakPolarHBondContact OD1-CB 3.36Å; D314-R316 PolarHBondContact OD1-N 3.22Å
315G96Very high95.5Very high1 Ų156 Ų561%0.0135%0.351CS..SBendtrans83.97.7-175.100000113.6S231 L311S231-G315 VanDerWaalsContact CB-O 3.28Å; S231-G315 WeakPolarHBondContact CB-O 3.43Å; S231-G315 PolarHBondContact OG-O 2.93Å; L311-G315 WeakPolarHBondContact O-CA 3.22Å; L311-G315 PolarHBondContact O-N 3.21Å
316R96.8Very high95.7Very high97 Ų9757.9 Ų57.937%0.36636%0.362SS..SBendtrans-119.3172.6-179.3-55.4176.958150.81.7110.3E291 L311 D314E291-R316 VanDerWaalsContact CD-CD 3.43Å; E291-R316 VanDerWaalsContact CD-CZ 3.48Å; E291-R316 WeakPolarHBondContact OE1-CD 3.44Å; E291-R316 IonicContact OE1-CZ 3.79Å; E291-R316 IonicContact OE1-NE 3.38Å; E291-R316 PolarHBondContact OE1-NE 3.23Å; E291-R316 IonicContact OE1-NH1 2.52Å; E291-R316 PolarHBondContact OE1-NH1 3.4Å; E291-R316 IonicContact OE1-NH2 3.26Å; E291-R316 VanDerWaalsContact OE2-CD 3.31Å; E291-R316 WeakPolarHBondContact OE2-CD 3.28Å; E291-R316 VanDerWaalsContact OE2-CG 3.3Å; E291-R316 WeakPolarHBondContact OE2-CG 3.13Å; E291-R316 IonicContact OE2-NE 3.83Å; L311-R316 WeakPolarHBondContact CA-O 3.44Å; D314-R316 VanDerWaalsContact C-N 3.32Å; D314-R316 WeakPolarHBondContact OD1-CA 3.29Å; D314-R316 WeakPolarHBondContact OD1-CB 3.36Å; D314-R316 PolarHBondContact OD1-N 3.22Å
317L97.8Very high95.8Very high8 Ų855.9 Ų55.94%0.04234%0.338CS..  trans-118.3133.2173.2-61.7178.6000110.5M233 S293 H294 L307 D310 L311 A336 A338M233-L317 HydrophobicContact CG-CD1 4.17Å; M233-L317 HydrophobicContact SD-CD1 4.09Å; M233-L317 HydrophobicContact SD-CD2 4.08Å; S293-L317 WeakPolarHBondContact CB-O 3.43Å; S293-L317 PolarHBondContact OG-N 3.49Å; H294-L317 VanDerWaalsContact O-CB 3.31Å; H294-L317 WeakPolarHBondContact O-CB 3.28Å; L307-L317 HydrophobicContact CD1-CD1 4.39Å; L307-L317 HydrophobicContact CD1-CD2 3.7Å; D310-L317 WeakPolarHBondContact OD2-CA 3.4Å; L311-L317 HydrophobicContact CB-CD2 4.12Å; L311-L317 HydrophobicContact CD1-CD2 4.17Å; L311-L317 HydrophobicContact CD1-CG 4.5Å; L317-A336 HydrophobicContact CD1-CB 3.69Å; L317-A338 HydrophobicContact CD1-CB 3.75Å; L317-A338 HydrophobicContact CG-CB 3.79Å
318D95.2Very high95.9Very high110 Ų11062.1 Ų62.159%0.58837%0.367SS*.  trans-92.7128.3172.8-78-23.2000110.5Q295 D310Q295-D318 PolarHBondContact NE2-O 2.96Å; Q295-D318 PolarHBondContact OE1-O 2.63Å; D310-D318 PolarHBondContact OD2-N 2.83Å
319S93.7Very high95.8Very high37 Ų3769.8 Ų69.826%0.25940%0.401SS..  trans-125.4140.7178.9-164.90000112.6H294 Q295 T296H294-S319 PolarHBondContact CD2-OG 3.33Å; H294-S319 VanDerWaalsContact O-CB 3.28Å; H294-S319 WeakPolarHBondContact O-CB 3.46Å; Q295-S319 PolarHBondContact OE1-OG 3.1Å; T296-S319 PolarHBondContact N-OG 3.44Å; T296-S319 PolarHBondContact OG1-OG 2.87Å
320P89.3Confident95.7Very high93 Ų9368.3 Ų68.360%0.60440%0.395SS*.  trans-56.8148.8161.8-2133.1000111.8Q295Q295-P320 VanDerWaalsContact OE1-CD 3.29Å
321T88.5Confident95.6Very high146 Ų14671.1 Ų71.190%0.89641%0.408SS*.SBendtrans-71.9132.7176.554.40000111.7
322G92.8Very high95.5Very high38 Ų3872.9 Ų72.939%0.39242%0.415SS..SBendtrans85.7-168.217200000114.6P254P254-G322 VanDerWaalsContact CD-O 3.3Å; P254-G322 WeakPolarHBondContact CD-O 3.32Å
323S97.1Very high95.6Very high67 Ų6770.4 Ų70.447%0.46940%0.403SS..PPolyproline II helixtrans-75.9149.5-172.9-36.40000112.5N252 E253N252-S323 CarbonylContact O-C 3.53Å; N252-S323 WeakPolarHBondContact O-CA 3.37Å; E253-S323 WeakPolarHBondContact CB-OG 3.38Å; E253-S323 PolarHBondContact OE2-OG 3.36Å
324S97.4Very high95.6Very high17 Ų1765.6 Ų65.612%0.11937%0.374CS..PPolyproline II helixtrans-73.1152172.377.30000111N252N252-S324 PolarHBondContact N-OG 3.21Å; N252-S324 PolarHBondContact O-N 3.08Å; N252-S324 PolarHBondContact O-OG 3.09Å
325P96.5Very high95.7Very high108 Ų10862.7 Ų62.770%0.70136%0.358SS*.PPolyproline II helixtrans-62.3152.516828.4-34.7000110.8T327P325-T327 PolarHBondContact O-N 3.5Å
326P97.8Very high95.9Very high86 Ų8662.6 Ų62.656%0.55836%0.358SS*.PPolyproline II helixtrans-58.7136.6170.3-23.934.2000112.5H250H250-P326 WeakPolarHBondContact O-CA 3.28Å
327T97.9Very high95.9Very high17 Ų1758 Ų5810%0.10434%0.34CS..PPolyproline II helixtrans-61.4143.8177.947.20000112.3G248 G249 H250 P325 V333G248-T327 CarbonylContact C-O 3.51Å; G248-T327 WeakPolarHBondContact CA-O 3.37Å; G249-T327 PolarHBondContact N-O 3.04Å; G249-T327 PolarHBondContact N-OG1 3.12Å; H250-T327 PolarHBondContact N-OG1 3.37Å; H250-T327 VanDerWaalsContact N-OG1 3.12Å; H250-T327 WeakPolarHBondContact O-CG2 3.35Å; H250-T327 PolarHBondContact O-N 3.08Å; H250-T327 PolarHBondContact O-OG1 2.88Å; P325-T327 PolarHBondContact O-N 3.5Å; T327-V333 HydrophobicContact CG2-CB 3.66Å; T327-V333 HydrophobicContact CG2-CG1 3.63Å
328Q97.1Very high96Very high141 Ų14157.6 Ų57.666%0.65934%0.338SS*.PPolyproline II helixtrans-77.1158.5168.1-58.5-173.41.700110.9G330 E331Q328-G330 PolarHBondContact O-N 3.39Å; Q328-E331 HydrophobicContact CB-CG 4.17Å; Q328-E331 WeakPolarHBondContact CB-OE2 3.27Å; Q328-E331 PolarHBondContact N-OE2 2.91Å; Q328-E331 VanDerWaalsContact N-OE2 3.08Å; Q328-E331 WeakPolarHBondContact O-CB 3.24Å; Q328-E331 PolarHBondContact O-N 3.05Å
329K96.2Very high96.2Very high184 Ų18452.5 Ų52.580%0.831%0.311SS*.THydrogen-bonded Turntrans-56.7129.7174-173.4176.7-177.6175.20110.5
330G95.2Very high96.4Very high30 Ų3051.5 Ų51.531%0.30930%0.304SS..THydrogen-bonded Turntrans92.6-11.1-176.800000114.9K246 K301 Q328K246-G330 PolarHBondContact O-N 3.23Å; K301-G330 PolarHBondContact NZ-O 3.44Å; Q328-G330 PolarHBondContact O-N 3.39Å
331E95.2Very high96.7Very high86 Ų8647.3 Ų47.340%0.40228%0.277SS..  trans-89.5161.1175.4-59-171.7144.100111.6D245 K246 Q328D245-E331 VanDerWaalsContact O-O 3.04Å; K246-E331 WeakPolarHBondContact CA-O 3.48Å; Q328-E331 HydrophobicContact CB-CG 4.17Å; Q328-E331 WeakPolarHBondContact CB-OE2 3.27Å; Q328-E331 PolarHBondContact N-OE2 2.91Å; Q328-E331 VanDerWaalsContact N-OE2 3.08Å; Q328-E331 WeakPolarHBondContact O-CB 3.24Å; Q328-E331 PolarHBondContact O-N 3.05Å
332K96.1Very high97.2Very high36 Ų3643.1 Ų43.116%0.15725%0.254CS..  trans-131.8149.8171.8-66.3-165.4173-146.40107.1D245 K246 P300D245-K332 HydrophobicContact CB-CD 4.14Å; D245-K332 HydrophobicContact CB-CG 4.27Å; D245-K332 IonicContact OD2-NZ 2.73Å; D245-K332 PolarHBondContact OD2-NZ 2.82Å; K246-K332 HydrophobicContact CG-CG 3.95Å; P300-K332 HydrophobicContact CG-CB 3.96Å
333V97.4Very high97.4Very high14 Ų1441.3 Ų41.39%0.08524%0.235CC..  trans-127.1147.7173.966.40000109.7N238 A297 T327N238-V333 HydrophobicContact CB-CG1 3.68Å; N238-V333 WeakPolarHBondContact CB-O 3.4Å; N238-V333 PolarHBondContact N-O 2.67Å; A297-V333 HydrophobicContact CB-CG2 3.66Å; T327-V333 HydrophobicContact CG2-CB 3.66Å; T327-V333 HydrophobicContact CG2-CG1 3.63Å
334A97.9Very high97.5Very high0 Ų041.3 Ų41.30%023%0.233CC..EExtended strand (participates in β ladder)trans-134.4159.8176.300000109.8M236 V237 N252 A297 F298 P300M236-A334 CarbonylContact O-C 3.52Å; M236-A334 WeakPolarHBondContact O-CA 3.26Å; M236-A334 WeakPolarHBondContact O-CB 3.15Å; V237-A334 HydrophobicContact CG2-CB 4.22Å; N252-A334 PolarHBondContact ND2-O 3.25Å; A297-A334 CarbonylContact C-O 3.58Å; A297-A334 VanDerWaalsContact CA-O 3.3Å; A297-A334 WeakPolarHBondContact CA-O 3.42Å; F298-A334 HydrophobicContact CD1-CB 4.01Å; F298-A334 WeakPolarHBondContact CD1-O 3.28Å; F298-A334 HydrophobicContact CD2-CB 4.46Å; F298-A334 HydrophobicContact CE1-CB 3.51Å; F298-A334 HydrophobicContact CE2-CB 4.01Å; F298-A334 HydrophobicContact CG-CB 4.46Å; F298-A334 HydrophobicContact CZ-CB 3.51Å; F298-A334 PolarHBondContact N-O 3.39Å; F298-A334 PolarHBondContact O-N 2.89Å; P300-A334 HydrophobicContact CB-CB 4.3Å; P300-A334 HydrophobicContact CG-CB 4.3Å
335A98.5Very high97.5Very high0 Ų042.1 Ų42.10%024%0.241CC..EExtended strand (participates in β ladder)trans-122.1159.1174.300000110.5T235 M236 V267 L269 I282 Q295T235-A335 WeakPolarHBondContact CA-O 3.22Å; M236-A335 PolarHBondContact N-O 2.86Å; M236-A335 PolarHBondContact O-N 2.7Å; V267-A335 HydrophobicContact CB-CB 3.93Å; V267-A335 HydrophobicContact CG1-CB 3.59Å; V267-A335 HydrophobicContact CG2-CB 4.3Å; L269-A335 HydrophobicContact CD1-CB 4.42Å; L269-A335 HydrophobicContact CD2-CB 3.95Å; L269-A335 HydrophobicContact CG-CB 4.18Å; I282-A335 HydrophobicContact CD1-CB 4.07Å; Q295-A335 WeakPolarHBondContact O-CA 3.13Å
336A98.6Very high97.5Very high0 Ų042.9 Ų42.90%024%0.238CC..EExtended strand (participates in β ladder)trans-132.1144.8172.700000110.5M233 F234 T235 H294 Q295 F298 L307 L317M233-A336 HydrophobicContact CG-CB 4.24Å; M233-A336 HydrophobicContact SD-CB 4.09Å; F234-A336 CarbonylContact O-C 3.55Å; F234-A336 WeakPolarHBondContact O-CA 3.44Å; T235-A336 HydrophobicContact CG2-CB 3.78Å; H294-A336 CarbonylContact C-O 3.58Å; H294-A336 WeakPolarHBondContact CA-O 3.22Å; H294-A336 WeakPolarHBondContact CB-O 3.24Å; Q295-A336 HydrophobicContact CB-CB 4.16Å; Q295-A336 PolarHBondContact N-O 2.67Å; Q295-A336 PolarHBondContact O-N 3.22Å; F298-A336 HydrophobicContact CE1-CB 4.28Å; L307-A336 HydrophobicContact CD1-CB 4.08Å; L307-A336 HydrophobicContact CD2-CB 4.02Å; L317-A336 HydrophobicContact CD1-CB 3.69Å
337L98.8Very high97.5Very high0 Ų045.1 Ų45.10%024%0.239CC..EExtended strand (participates in β ladder)trans-130.7125.8174.4179.168.9000107.9M233 F234 I282 A284 V292 S293 H294 F353M233-L337 CarbonylContact C-O 3.56Å; M233-L337 WeakPolarHBondContact CA-O 3.41Å; F234-L337 PolarHBondContact N-O 3.11Å; F234-L337 PolarHBondContact O-N 2.78Å; I282-L337 HydrophobicContact CB-CD2 4.47Å; I282-L337 HydrophobicContact CD1-CB 3.8Å; I282-L337 HydrophobicContact CG1-CB 4.13Å; A284-L337 HydrophobicContact CB-CD2 3.92Å; V292-L337 HydrophobicContact CG1-CD1 3.61Å; S293-L337 WeakPolarHBondContact O-CD1 3.49Å; H294-L337 HydrophobicContact CB-CD1 4.25Å; L337-F353 HydrophobicContact CD2-CD1 4.02Å; L337-F353 HydrophobicContact CD2-CE1 4.35Å; L337-F353 HydrophobicContact CG-CE1 4.36Å
338A98.7Very high97.5Very high0 Ų047.7 Ų47.70%025%0.252CS..EExtended strand (participates in β ladder)trans-117.7135.2175.300000110.5I232 M233 S293 L311 L317I232-A338 VanDerWaalsContact O-CA 3.3Å; I232-A338 WeakPolarHBondContact O-CA 3.44Å; M233-A338 HydrophobicContact CB-CB 4.24Å; S293-A338 PolarHBondContact N-O 3.47Å; S293-A338 PolarHBondContact O-N 3.4Å; S293-A338 VanDerWaalsContact O-O 3.11Å; L311-A338 HydrophobicContact CD1-CB 4.09Å; L317-A338 HydrophobicContact CD1-CB 3.75Å; L317-A338 HydrophobicContact CG-CB 3.79Å
339V98.6Very high97.5Very high3 Ų342.5 Ų42.52%0.01823%0.229CC..EExtended strand (participates in β ladder)trans-120.3131172.6-170.50000107.9S231 I232 A284 R290 E291 V292 L351 F353S231-V339 WeakPolarHBondContact CA-O 3.34Å; I232-V339 PolarHBondContact N-O 3.41Å; I232-V339 PolarHBondContact O-N 2.8Å; A284-V339 HydrophobicContact CB-CG2 3.33Å; R290-V339 HydrophobicContact CB-CG1 4.37Å; E291-V339 CarbonylContact O-C 3.49Å; E291-V339 WeakPolarHBondContact O-CA 3.37Å; V292-V339 HydrophobicContact CG2-CG1 4.44Å; V292-V339 HydrophobicContact CG2-CG2 4.4Å; V339-L351 HydrophobicContact CB-CD1 4.35Å; V339-L351 HydrophobicContact CB-CD2 4.4Å; V339-L351 HydrophobicContact CG1-CD2 3.75Å; V339-L351 VanDerWaalsContact O-CD1 3.26Å; V339-L351 WeakPolarHBondContact O-CD1 3.43Å; V339-F353 HydrophobicContact CB-CE1 4.26Å; V339-F353 HydrophobicContact CB-CE2 4.38Å; V339-F353 HydrophobicContact CB-CZ 3.74Å; V339-F353 HydrophobicContact CG2-CD1 4.26Å; V339-F353 HydrophobicContact CG2-CE1 3.52Å; V339-F353 HydrophobicContact CG2-CE2 4.25Å; V339-F353 HydrophobicContact CG2-CZ 3.49Å; V339-F353 VanDerWaalsContact CG2-CZ 3.49Å
340S97.8Very high97.5Very high15 Ų1535.2 Ų35.211%0.10520%0.201CC..EExtended strand (participates in β ladder)trans-116.2149.2179.164.10000111.7V230 S231 R290 E291V230-S340 CarbonylContact O-C 3.56Å; V230-S340 VanDerWaalsContact O-CA 3.31Å; V230-S340 WeakPolarHBondContact O-CA 3.3Å; S231-S340 VanDerWaalsContact OG-CB 3.29Å; S231-S340 WeakPolarHBondContact OG-CB 3.41Å; R290-S340 WeakPolarHBondContact CA-O 3.47Å; E291-S340 VanDerWaalsContact CB-OG 3.27Å; E291-S340 WeakPolarHBondContact CB-OG 3.32Å; E291-S340 PolarHBondContact N-O 2.91Å; E291-S340 VanDerWaalsContact N-O 3.16Å; E291-S340 PolarHBondContact O-N 2.88Å; E291-S340 PolarHBondContact O-OG 2.84Å; E291-S340 PolarHBondContact OE2-OG 3.14Å
341C97.5Very high97.6Very high6 Ų633.9 Ų33.94%0.04119%0.187CC..EExtended strand (participates in β ladder)trans-148.5158.1171.267.30000111.3D229 V230 L351D229-C341 WeakPolarHBondContact CA-O 3.45Å; V230-C341 PolarHBondContact N-O 3.4Å; V230-C341 PolarHBondContact O-N 2.9Å; C341-L351 HydrophobicContact CB-CD2 3.73Å
342S97.4Very high97.7Very high58 Ų5830.2 Ų30.241%0.40617%0.17SC..EExtended strand (participates in β ladder)trans-89.1135.4165.5-155.20000110.2D229 N349D229-S342 WeakPolarHBondContact OD1-CB 3.33Å; D229-S342 PolarHBondContact OD1-OG 3.2Å; S342-N349 PolarHBondContact O-ND2 2.9Å
343V98Very high97.9Very high0 Ų028.5 Ų28.50%016%0.162CC..EExtended strand (participates in β ladder)trans-118.5105.8178.5-167.40000108.2I220 N222 A227 L228 V230 N349I220-V343 HydrophobicContact CB-CG2 4.35Å; I220-V343 HydrophobicContact CG2-CG2 3.97Å; N222-V343 HydrophobicContact CB-CB 4.18Å; N222-V343 HydrophobicContact CB-CG1 3.53Å; N222-V343 PolarHBondContact ND2-O 3.02Å; A227-V343 WeakPolarHBondContact CA-O 3.38Å; L228-V343 PolarHBondContact N-O 3.12Å; L228-V343 PolarHBondContact O-N 2.95Å; V230-V343 HydrophobicContact CB-CG2 4.26Å; V230-V343 HydrophobicContact CG2-CG2 3.87Å; V343-N349 HydrophobicContact CB-CB 4.42Å; V343-N349 HydrophobicContact CG1-CB 4.15Å; V343-N349 HydrophobicContact CG2-CB 3.87Å
344P98Very high97.9Very high66 Ų6627.9 Ų27.943%0.42916%0.158SC..  trans-59.2160.7-179.1-22.932.5000112.9N222 L346 K347N222-P344 PolarHBondContact ND2-O 2.66Å; P344-L346 PolarHBondContact O-N 3.34Å; P344-K347 HydrophobicContact CB-CB 4.04Å; P344-K347 HydrophobicContact CB-CG 3.9Å; P344-K347 HydrophobicContact CG-CB 4.41Å; P344-K347 HydrophobicContact CG-CG 4.47Å; P344-K347 PolarHBondContact O-N 3.47Å
345A97.8Very high98Very high34 Ų3427.9 Ų27.928%0.28116%0.158SC..THydrogen-bonded Turntrans-53.1133.9173.600000111.4N224 D225 K347N224-A345 CarbonylContact O-C 3.52Å; N224-A345 WeakPolarHBondContact O-CA 3.47Å; D225-A345 WeakPolarHBondContact O-CB 3.29Å; A345-K347 WeakPolarHBondContact O-CG 3.19Å; A345-K347 PolarHBondContact O-N 3.18Å
346L97.7Very high98Very high124 Ų12427.9 Ų27.965%0.64916%0.158SC*.THydrogen-bonded Turntrans55.829.1177.9-52.4175.1000114.1N222 K223 N224 P344N222-L346 CarbonylContact O-C 3.55Å; N222-L346 WeakPolarHBondContact O-CA 3.41Å; N222-L346 PolarHBondContact O-N 2.91Å; N222-L346 VanDerWaalsContact O-N 3.13Å; K223-L346 WeakPolarHBondContact O-CD2 3.35Å; N224-L346 WeakPolarHBondContact O-CD2 3.21Å; N224-L346 PolarHBondContact O-N 2.94Å; P344-L346 PolarHBondContact O-N 3.34Å
347K97.8Very high98Very high133 Ų13328 Ų2858%0.57816%0.159SC*.  trans-125.9168.3-179.3-65.7-61.6-178.6-178.70112.3N222 P344 A345N222-K347 PolarHBondContact N-O 3.45Å; N222-K347 PolarHBondContact O-N 3.28Å; P344-K347 HydrophobicContact CB-CB 4.04Å; P344-K347 HydrophobicContact CB-CG 3.9Å; P344-K347 HydrophobicContact CG-CB 4.41Å; P344-K347 HydrophobicContact CG-CG 4.47Å; P344-K347 PolarHBondContact O-N 3.47Å; A345-K347 WeakPolarHBondContact O-CG 3.19Å; A345-K347 PolarHBondContact O-N 3.18Å
348L96.6Very high98Very high72 Ų7228 Ų2838%0.37716%0.159SC..EExtended strand (participates in β ladder)trans-107.3144.7174.2-174.886000109.3Q24 D219 I220 E221Q24-L348 HydrophobicContact CB-CD1 4.48Å; Q24-L348 HydrophobicContact CG-CD1 4.39Å; Q24-L348 HydrophobicContact CG-CD2 4.17Å; D219-L348 HydrophobicContact CB-CD1 4.19Å; I220-L348 WeakPolarHBondContact O-CA 3.38Å; E221-L348 HydrophobicContact CB-CD1 4.25Å; E221-L348 HydrophobicContact CG-CD1 3.37Å
349N96.8Very high98Very high32 Ų3228.1 Ų28.117%0.17116%0.159CC..EExtended strand (participates in β ladder)trans-139.8166.7160.7-145.3-7.4000110.8I220 R290 S342 V343I220-N349 PolarHBondContact N-O 2.9Å; I220-N349 PolarHBondContact O-N 3.41Å; I220-N349 VanDerWaalsContact O-N 3.1Å; R290-N349 PolarHBondContact NH1-ND2 3.46Å; R290-N349 VanDerWaalsContact NH1-ND2 3.1Å; R290-N349 PolarHBondContact NH2-ND2 2.85Å; R290-N349 PolarHBondContact NH2-OD1 2.74Å; S342-N349 PolarHBondContact O-ND2 2.9Å; V343-N349 HydrophobicContact CB-CB 4.42Å; V343-N349 HydrophobicContact CG1-CB 4.15Å; V343-N349 HydrophobicContact CG2-CB 3.87Å
350S96.9Very high97.9Very high31 Ų3128.3 Ų28.322%0.21716%0.16CC..EExtended strand (participates in β ladder)trans-134.1143.1-176.964.30000114.6W218 R290W218-S350 CarbonylContact O-C 3.49Å; W218-S350 WeakPolarHBondContact O-CA 3.48Å; R290-S350 PolarHBondContact NE-O 3.38Å; R290-S350 VanDerWaalsContact NE-O 3.11Å; R290-S350 PolarHBondContact NH2-O 3.33Å
351L98.1Very high97.9Very high1 Ų133.3 Ų33.31%0.00518%0.177CC..EExtended strand (participates in β ladder)trans-115.4141.2173.2-56.9-179.4000110.6V217 W218 I220 I232 R290 V339 C341 F353V217-L351 CarbonylContact C-O 3.58Å; V217-L351 WeakPolarHBondContact CA-O 3.4Å; W218-L351 HydrophobicContact CB-CB 4.31Å; W218-L351 PolarHBondContact N-O 2.91Å; W218-L351 PolarHBondContact O-N 3.32Å; I220-L351 HydrophobicContact CD1-CD1 3.95Å; I220-L351 HydrophobicContact CD1-CG 3.89Å; I232-L351 HydrophobicContact CB-CD1 3.94Å; I232-L351 HydrophobicContact CD1-CD1 4.01Å; I232-L351 HydrophobicContact CG1-CD1 3.86Å; R290-L351 VanDerWaalsContact CD-CD2 3.43Å; R290-L351 VanDerWaalsContact NE-CD2 3.33Å; V339-L351 HydrophobicContact CB-CD1 4.35Å; V339-L351 HydrophobicContact CB-CD2 4.4Å; V339-L351 HydrophobicContact CG1-CD2 3.75Å; V339-L351 VanDerWaalsContact O-CD1 3.26Å; V339-L351 WeakPolarHBondContact O-CD1 3.43Å; C341-L351 HydrophobicContact CB-CD2 3.73Å; L351-F353 HydrophobicContact CB-CE2 3.97Å
352E97.8Very high97.9Very high10 Ų1033.1 Ų33.15%0.04718%0.176CC..EExtended strand (participates in β ladder)trans-119.4127-175.2-58.7175.3174.100110.3V217 A284 L394 Y397 K398V217-E352 HydrophobicContact CG1-CG 4.47Å; A284-E352 WeakPolarHBondContact CB-O 3.38Å; E352-L394 HydrophobicContact CB-CD2 3.99Å; E352-Y397 HydrophobicContact CG-CE1 4.29Å; E352-Y397 PolarHBondContact OE1-OH 3.38Å; E352-K398 IonicContact OE1-NZ 3.69Å
353F98.8Very high97.9Very high0 Ų031.8 Ų31.80%017%0.165CC..EExtended strand (participates in β ladder)trans-125.1151.5175.2-62.4-101.4000110.4F135 V215 F216 W218 I232 F234 A283 L337 V339 L351F135-F353 HydrophobicContact CE1-CD2 4.32Å; F135-F353 HydrophobicContact CE1-CG 4.24Å; V215-F353 CarbonylContact C-O 3.48Å; V215-F353 WeakPolarHBondContact CA-O 3.49Å; V215-F353 WeakPolarHBondContact CG1-O 3.46Å; F216-F353 HydrophobicContact CB-CB 4.29Å; F216-F353 PolarHBondContact N-O 3.32Å; F216-F353 PolarHBondContact O-N 3.33Å; W218-F353 AromaticContact CD1-CD2 3.78Å; W218-F353 AromaticContact CD1-CE2 3.91Å; I232-F353 HydrophobicContact CB-CE2 4.11Å; I232-F353 HydrophobicContact CB-CZ 4.02Å; I232-F353 HydrophobicContact CG2-CE2 3.93Å; I232-F353 HydrophobicContact CG2-CZ 3.94Å; I232-F353 VanDerWaalsContact O-CZ 3.28Å; I232-F353 WeakPolarHBondContact O-CZ 3.12Å; F234-F353 HydrophobicContact CB-CD1 3.91Å; F234-F353 HydrophobicContact CB-CE1 4.03Å; F234-F353 HydrophobicContact CD1-CB 4.41Å; F234-F353 HydrophobicContact CD1-CD1 4.26Å; A283-F353 CarbonylContact O-C 3.58Å; A283-F353 VanDerWaalsContact O-CA 3.29Å; A283-F353 WeakPolarHBondContact O-CA 3.47Å; L337-F353 HydrophobicContact CD2-CD1 4.02Å; L337-F353 HydrophobicContact CD2-CE1 4.35Å; L337-F353 HydrophobicContact CG-CE1 4.36Å; V339-F353 HydrophobicContact CB-CE1 4.26Å; V339-F353 HydrophobicContact CB-CE2 4.38Å; V339-F353 HydrophobicContact CB-CZ 3.74Å; V339-F353 HydrophobicContact CG2-CD1 4.26Å; V339-F353 HydrophobicContact CG2-CE1 3.52Å; V339-F353 HydrophobicContact CG2-CE2 4.25Å; V339-F353 HydrophobicContact CG2-CZ 3.49Å; V339-F353 VanDerWaalsContact CG2-CZ 3.49Å; L351-F353 HydrophobicContact CB-CE2 3.97Å
354C98.8Very high97.8Very high0 Ų032 Ų320%017%0.166CC..EExtended strand (participates in β ladder)trans-123.9141.6170.5179.80000110.5A214 I282 A283 L394A214-C354 WeakPolarHBondContact O-CA 3.07Å; A214-C354 PolarHBondContact O-SG 2.91Å; I282-C354 WeakPolarHBondContact CA-O 3.2Å; A283-C354 HydrophobicContact CB-CB 4.44Å; A283-C354 PolarHBondContact N-O 2.94Å; A283-C354 PolarHBondContact O-N 3Å; C354-L394 HydrophobicContact CB-CD1 3.98Å; C354-L394 HydrophobicContact CB-CD2 4Å; C354-L394 HydrophobicContact CB-CG 3.76Å
355L98.9Very high97.6Very high0 Ų031 Ų310%017%0.168CC..EExtended strand (participates in β ladder)trans-114117.7161175.461.1000108I107 F115 A213 A214 F216 F234 M236 C281 I282 W357I107-L355 HydrophobicContact CD1-CD2 3.9Å; F115-L355 HydrophobicContact CE1-CD2 4.11Å; A213-L355 CarbonylContact C-O 3.57Å; A213-L355 VanDerWaalsContact CA-O 3.32Å; A213-L355 WeakPolarHBondContact CA-O 3.34Å; A214-L355 PolarHBondContact N-O 3.49Å; A214-L355 PolarHBondContact O-N 2.85Å; F216-L355 HydrophobicContact CE2-CB 3.92Å; F234-L355 HydrophobicContact CE1-CB 4.23Å; F234-L355 HydrophobicContact CZ-CB 4.43Å; F234-L355 HydrophobicContact CZ-CD2 4.49Å; M236-L355 HydrophobicContact CE-CD1 3.81Å; M236-L355 HydrophobicContact CE-CD2 3.74Å; M236-L355 HydrophobicContact CE-CG 4.46Å; C281-L355 WeakPolarHBondContact O-CA 3.14Å; I282-L355 HydrophobicContact CG2-CD1 4.22Å; L355-W357 HydrophobicContact CD2-CZ3 4.33Å; L355-W357 HydrophobicContact CG-CE3 4.11Å; L355-W357 HydrophobicContact CG-CZ3 4.05Å
356A98.8Very high97.4Very high0 Ų030.8 Ų30.80%016%0.164CC..EExtended strand (participates in β ladder)trans-122.6154.317400000110.7P212 A213 L280 C281 L389P212-A356 WeakPolarHBondContact O-CA 3.41Å; A213-A356 HydrophobicContact CB-CB 4.13Å; L280-A356 CarbonylContact C-O 3.48Å; L280-A356 WeakPolarHBondContact CA-O 3.48Å; C281-A356 HydrophobicContact CB-CB 4.38Å; C281-A356 PolarHBondContact N-O 3.11Å; C281-A356 PolarHBondContact O-N 2.84Å; A356-L389 HydrophobicContact CB-CB 4.13Å
357W98.6Very high97.2Very high3 Ų327.2 Ų27.21%0.01116%0.157CC..EExtended strand (participates in β ladder)trans-140.8124175.554.292.4000111.7L99 G104 G105 I107 L120 P212 T279 L280 L355L99-W357 HydrophobicContact CB-CH2 4.34Å; G104-W357 PolarHBondContact O-NE1 2.76Å; G105-W357 WeakPolarHBondContact O-CZ2 3.36Å; G105-W357 PolarHBondContact O-NE1 2.54Å; I107-W357 HydrophobicContact CD1-CD2 4.07Å; I107-W357 HydrophobicContact CD1-CE3 3.66Å; I107-W357 HydrophobicContact CD1-CH2 4.44Å; I107-W357 HydrophobicContact CD1-CZ3 3.87Å; I107-W357 HydrophobicContact CG1-CE3 4.48Å; I107-W357 HydrophobicContact CG1-CZ3 4.44Å; L120-W357 HydrophobicContact CD2-CD2 4.34Å; L120-W357 HydrophobicContact CD2-CG 4Å; P212-W357 HydrophobicContact CB-CD2 4.12Å; P212-W357 HydrophobicContact CB-CG 4.03Å; P212-W357 HydrophobicContact CB-CZ2 4.25Å; P212-W357 VanDerWaalsContact CB-NE1 3.26Å; P212-W357 WeakPolarHBondContact CB-O 3.39Å; P212-W357 WeakPolarHBondContact CG-O 3.09Å; P212-W357 PolarHBondContact O-N 3.22Å; T279-W357 WeakPolarHBondContact O-CA 3.34Å; L280-W357 HydrophobicContact CD2-CB 3.46Å; L280-W357 VanDerWaalsContact CD2-CB 3.46Å; L280-W357 HydrophobicContact CD2-CG 4.48Å; L355-W357 HydrophobicContact CD2-CZ3 4.33Å; L355-W357 HydrophobicContact CG-CE3 4.11Å; L355-W357 HydrophobicContact CG-CZ3 4.05Å
358D98.6Very high97Very high0 Ų025.7 Ų25.70%015%0.152CC..EExtended strand (participates in β ladder)trans-105.7111-177.8-170.627.6000110.9Y278 T279 P360 Y375 G383 D384 A385 S386 L389Y278-D358 CarbonylContact C-O 3.31Å; Y278-D358 WeakPolarHBondContact CA-O 3.34Å; Y278-D358 VanDerWaalsContact CB-O 3.29Å; Y278-D358 WeakPolarHBondContact CB-O 3.47Å; T279-D358 PolarHBondContact N-O 2.83Å; T279-D358 PolarHBondContact O-N 2.85Å; D358-P360 VanDerWaalsContact OD1-CD 3.29Å; D358-P360 WeakPolarHBondContact OD1-CD 3.19Å; D358-Y375 WeakPolarHBondContact CA-OH 3.47Å; D358-Y375 VanDerWaalsContact OD1-CE2 3.31Å; D358-Y375 WeakPolarHBondContact OD1-CE2 3.37Å; D358-Y375 PolarHBondContact OD1-OH 2.81Å; D358-G383 WeakPolarHBondContact OD2-CA 3.16Å; D358-D384 PolarHBondContact OD2-N 3.03Å; D358-A385 WeakPolarHBondContact OD2-CB 3.46Å; D358-A385 PolarHBondContact OD2-N 3.12Å; D358-S386 VanDerWaalsContact CB-OG 3.25Å; D358-S386 WeakPolarHBondContact CB-OG 3.36Å; D358-L389 HydrophobicContact CB-CD1 4.34Å
359M98.2Very high96.9Very high3 Ų328.8 Ų28.82%0.01516%0.159CC..  trans-13967.4174.1-171.8-167.6-7600109.4L120 N276 Y278 I362 R373 Y375L120-M359 HydrophobicContact CB-CE 4.05Å; L120-M359 VanDerWaalsContact O-SD 3.33Å; N276-M359 HydrophobicContact CB-CE 4.17Å; N276-M359 HydrophobicContact CB-CG 4.41Å; N276-M359 HydrophobicContact CB-SD 3.88Å; N276-M359 WeakPolarHBondContact O-CE 3.43Å; Y278-M359 HydrophobicContact CD1-CE 3.39Å; Y278-M359 HydrophobicContact CE1-CE 4.19Å; Y278-M359 HydrophobicContact CG-CE 3.81Å; M359-I362 HydrophobicContact CG-CG2 3.91Å; M359-I362 HydrophobicContact SD-CG2 3.79Å; M359-R373 WeakPolarHBondContact O-CD 3.38Å; M359-R373 PolarHBondContact O-NE 3.29Å; M359-R373 VanDerWaalsContact O-NE 3.13Å; M359-R373 PolarHBondContact SD-NH2 3.43Å; M359-R373 VanDerWaalsContact SD-NH2 3.36Å; M359-Y375 PolarHBondContact N-OH 3.13Å
360P97.8Very high96.8Very high6 Ų631.1 Ų31.14%0.03917%0.169CC..  trans-77.2-32.4-166.128-29.9000111.2D358 Y372 R373 Y375 A376D358-P360 VanDerWaalsContact OD1-CD 3.29Å; D358-P360 WeakPolarHBondContact OD1-CD 3.19Å; P360-Y372 CarbonylContact O-C 3.49Å; P360-Y372 WeakPolarHBondContact O-CA 3.16Å; P360-R373 PolarHBondContact O-N 3.01Å; P360-Y375 VanDerWaalsContact CA-OH 3.25Å; P360-Y375 WeakPolarHBondContact CA-OH 3.41Å; P360-Y375 HydrophobicContact CB-CE2 4.31Å; P360-Y375 WeakPolarHBondContact CD-OH 3.47Å; P360-A376 HydrophobicContact CB-CB 3.79Å
361R97.4Very high96.8Very high121 Ų12130.7 Ų30.746%0.45716%0.163SC..EExtended strand (participates in β ladder)trans-97.7126176-66.3170.262.8171.87109.4E370 Y372 D381R361-E370 HydrophobicContact CB-CG 4.48Å; R361-E370 IonicContact CZ-OE1 2.8Å; R361-E370 IonicContact CZ-OE2 3.84Å; R361-E370 IonicContact NE-OE1 3.12Å; R361-E370 PolarHBondContact NE-OE1 2.82Å; R361-E370 IonicContact NE-OE2 3.68Å; R361-E370 PolarHBondContact NE-OE2 3.01Å; R361-E370 VanDerWaalsContact NH2-CD 3.3Å; R361-E370 IonicContact NH2-OE1 2.59Å; R361-E370 PolarHBondContact NH2-OE1 2.99Å; R361-E370 VanDerWaalsContact NH2-OE1 3.13Å; R361-E370 IonicContact NH2-OE2 2.7Å; R361-E370 PolarHBondContact NH2-OE2 2.82Å; R361-Y372 HydrophobicContact CG-CD1 3.86Å; R361-Y372 HydrophobicContact CG-CE1 3.56Å; R361-D381 VanDerWaalsContact CD-O 3.24Å; R361-D381 WeakPolarHBondContact CD-O 3.32Å
362I97.3Very high96.8Very high1 Ų134.3 Ų34.31%0.00518%0.178CC..EExtended strand (participates in β ladder)trans-132.2150-179.957.7165.9000111.3P122 N276 M359 H371 R373 T440P122-I362 HydrophobicContact CB-CD1 4.39Å; P122-I362 HydrophobicContact CG-CB 3.87Å; P122-I362 HydrophobicContact CG-CD1 3.52Å; P122-I362 HydrophobicContact CG-CG1 4.23Å; P122-I362 HydrophobicContact CG-CG2 4.1Å; N276-I362 WeakPolarHBondContact OD1-CA 3.42Å; M359-I362 HydrophobicContact CG-CG2 3.91Å; M359-I362 HydrophobicContact SD-CG2 3.79Å; I362-H371 HydrophobicContact CD1-CB 4.38Å; I362-H371 HydrophobicContact CG1-CB 3.98Å; I362-H371 WeakPolarHBondContact CG1-O 3.25Å; I362-H371 PolarHBondContact N-O 2.77Å; I362-H371 PolarHBondContact O-N 3.49Å; I362-R373 HydrophobicContact CD1-CG 4.14Å; I362-R373 HydrophobicContact CG1-CG 4.4Å; I362-R373 HydrophobicContact CG2-CG 4.25Å; I362-T440 HydrophobicContact CD1-CG2 4.18Å
363T97.1Very high96.8Very high30 Ų3034 Ų3418%0.18418%0.176CC..EExtended strand (participates in β ladder)trans-121.3149161.962.50000109.5T275 N276 R369T275-T363 WeakPolarHBondContact CG2-OG1 3.5Å; N276-T363 PolarHBondContact ND2-O 3.34Å; N276-T363 PolarHBondContact OD1-N 2.9Å; N276-T363 PolarHBondContact OD1-OG1 2.76Å; T363-R369 WeakPolarHBondContact CG2-O 3.32Å
364F96.9Very high96.8Very high6 Ų634.2 Ų34.23%0.02618%0.177CC..  trans-79.6178.3166.7-64.4-78.8000110.6P122 S366 G367 H371 V438 Y483 D549 P551 W552P122-F364 HydrophobicContact CB-CD1 3.74Å; P122-F364 HydrophobicContact CB-CE1 3.57Å; P122-F364 HydrophobicContact CB-CZ 4.47Å; F364-S366 PolarHBondContact O-N 3.3Å; F364-S366 VanDerWaalsContact O-N 3.16Å; F364-G367 PolarHBondContact O-N 2.82Å; F364-H371 AromaticContact CD2-CD2 3.7Å; F364-H371 AromaticContact CD2-NE2 3.59Å; F364-H371 AromaticContact CE2-CD2 3.6Å; F364-H371 AromaticContact CE2-NE2 3.55Å; F364-V438 HydrophobicContact CE1-CG1 4.06Å; F364-V438 HydrophobicContact CE1-CG2 4.5Å; F364-V438 HydrophobicContact CZ-CG1 4.25Å; F364-V438 HydrophobicContact CZ-CG2 4.21Å; F364-Y483 HydrophobicContact CE1-CE2 4.07Å; F364-D549 WeakPolarHBondContact CB-O 3.4Å; F364-P551 HydrophobicContact CD1-CG 3.8Å; F364-P551 HydrophobicContact CD2-CG 4.34Å; F364-P551 HydrophobicContact CE1-CG 3.76Å; F364-P551 HydrophobicContact CE2-CG 4.31Å; F364-P551 VanDerWaalsContact CG-CD 3.48Å; F364-P551 HydrophobicContact CG-CG 4.09Å; F364-P551 HydrophobicContact CZ-CB 4.44Å; F364-P551 HydrophobicContact CZ-CG 4.03Å; F364-W552 HydrophobicContact CE2-CE3 4.49Å; F364-W552 AromaticContact CE2-CZ3 3.87Å; F364-W552 HydrophobicContact CE2-CZ3 3.87Å; F364-W552 HydrophobicContact CZ-CH2 4.44Å; F364-W552 AromaticContact CZ-CZ3 3.91Å; F364-W552 HydrophobicContact CZ-CZ3 3.91Å
365G93.8Very high96.7Very high45 Ų4534.2 Ų34.246%0.46418%0.177SC..THydrogen-bonded Turntrans-65.2-17.8-173.700000115.4G367 P547 D548G365-G367 VanDerWaalsContact C-N 3.3Å; G365-P547 PolarHBondContact N-O 3.33Å; G365-D548 CarbonylContact C-O 3.13Å; G365-D548 VanDerWaalsContact C-O 3.3Å
366S93.4Very high96.7Very high28 Ų2834.7 Ų34.720%0.19618%0.181CC..THydrogen-bonded Turntrans-65-32.9169.568.60000112.7F364 E368 D548 D549 E550F364-S366 PolarHBondContact O-N 3.3Å; F364-S366 VanDerWaalsContact O-N 3.16Å; S366-E368 PolarHBondContact O-N 3.24Å; S366-E368 PolarHBondContact OG-N 3Å; S366-E368 VanDerWaalsContact OG-N 3.07Å; S366-D548 PolarHBondContact N-O 2.94Å; S366-D549 WeakPolarHBondContact CB-O 3.47Å; S366-D549 PolarHBondContact N-O 3.39Å; S366-D549 VanDerWaalsContact N-O 3.16Å; S366-D549 PolarHBondContact OG-O 3.35Å; S366-E550 PolarHBondContact OG-OE2 2.86Å
367G93.8Very high96.6Very high50 Ų5039.7 Ų39.752%0.51520%0.199SC..  trans63.216.2-167.700000114.4F364 G365F364-G367 PolarHBondContact O-N 2.82Å; G365-G367 VanDerWaalsContact C-N 3.3Å
368E93.6Very high96.6Very high100 Ų10043 Ų4347%0.46721%0.213SC..  trans-80-35.6-171.8-75.9168.6-152.900113.1S366 R554S366-E368 PolarHBondContact O-N 3.24Å; S366-E368 PolarHBondContact OG-N 3Å; S366-E368 VanDerWaalsContact OG-N 3.07Å; E368-R554 VanDerWaalsContact CD-NH2 3.27Å; E368-R554 IonicContact OE1-CZ 2.74Å; E368-R554 IonicContact OE1-NH1 3.21Å; E368-R554 IonicContact OE1-NH2 3.48Å; E368-R554 PolarHBondContact OE1-NH2 3.49Å; E368-R554 IonicContact OE2-CZ 2.69Å; E368-R554 IonicContact OE2-NH2 3.88Å; E368-R554 PolarHBondContact OE2-NH2 3.08Å
369R93.4Very high96.6Very high138 Ų13844.9 Ų44.952%0.52122%0.221SC..  trans-133.4147.6178-59.8-162.1-167.5176.85.1112.3T363 E550T363-R369 WeakPolarHBondContact CG2-O 3.32Å; R369-E550 PolarHBondContact N-OE2 2.96Å
370E95.3Very high96.5Very high80 Ų8046.1 Ų46.137%0.37424%0.235SC..EExtended strand (participates in β ladder)trans-89.6137167.8-177.2170.384.500109.8R361 Y372R361-E370 HydrophobicContact CB-CG 4.48Å; R361-E370 IonicContact CZ-OE1 2.8Å; R361-E370 IonicContact CZ-OE2 3.84Å; R361-E370 IonicContact NE-OE1 3.12Å; R361-E370 PolarHBondContact NE-OE1 2.82Å; R361-E370 IonicContact NE-OE2 3.68Å; R361-E370 PolarHBondContact NE-OE2 3.01Å; R361-E370 VanDerWaalsContact NH2-CD 3.3Å; R361-E370 IonicContact NH2-OE1 2.59Å; R361-E370 PolarHBondContact NH2-OE1 2.99Å; R361-E370 VanDerWaalsContact NH2-OE1 3.13Å; R361-E370 IonicContact NH2-OE2 2.7Å; R361-E370 PolarHBondContact NH2-OE2 2.82Å; E370-Y372 HydrophobicContact CG-CE2 4.28Å; E370-Y372 VanDerWaalsContact OE1-CZ 3.32Å; E370-Y372 PolarHBondContact OE1-OH 3.24Å
371H96.8Very high96.4Very high23 Ų2349.2 Ų49.211%0.10625%0.251CS..EExtended strand (participates in β ladder)trans-124.3153.3173.9-55.5-101.5000109.5I362 F364 T440 E550I362-H371 HydrophobicContact CD1-CB 4.38Å; I362-H371 HydrophobicContact CG1-CB 3.98Å; I362-H371 WeakPolarHBondContact CG1-O 3.25Å; I362-H371 PolarHBondContact N-O 2.77Å; I362-H371 PolarHBondContact O-N 3.49Å; F364-H371 AromaticContact CD2-CD2 3.7Å; F364-H371 AromaticContact CD2-NE2 3.59Å; F364-H371 AromaticContact CE2-CD2 3.6Å; F364-H371 AromaticContact CE2-NE2 3.55Å; H371-T440 HydrophobicContact CB-CG2 3.91Å; H371-E550 IonicContact CD2-OE1 3.22Å; H371-E550 IonicContact CE1-OE1 3.24Å; H371-E550 PolarHBondContact CE1-OE1 2.64Å; H371-E550 IonicContact NE2-OE1 3.91Å; H371-E550 PolarHBondContact NE2-OE1 2.79Å
372Y97.8Very high96.4Very high77 Ų7751.3 Ų51.330%0.30226%0.263SS..EExtended strand (participates in β ladder)trans-110.9125.9178.5-63.4-96.5000108.8P360 R361 E370 D381 T440 E441P360-Y372 CarbonylContact O-C 3.49Å; P360-Y372 WeakPolarHBondContact O-CA 3.16Å; R361-Y372 HydrophobicContact CG-CD1 3.86Å; R361-Y372 HydrophobicContact CG-CE1 3.56Å; E370-Y372 HydrophobicContact CG-CE2 4.28Å; E370-Y372 VanDerWaalsContact OE1-CZ 3.32Å; E370-Y372 PolarHBondContact OE1-OH 3.24Å; Y372-D381 HydrophobicContact CD1-CB 3.7Å; Y372-D381 HydrophobicContact CE1-CB 3.76Å; Y372-T440 CarbonylContact O-C 3.54Å; Y372-T440 WeakPolarHBondContact O-CA 3.29Å; Y372-T440 WeakPolarHBondContact O-CB 3.18Å; Y372-E441 PolarHBondContact O-N 3.05Å
373R98.2Very high96.3Very high2 Ų252.4 Ų52.41%0.00828%0.275CS..BIsolated β-bridgetrans-65.5148.7175.1-70.1-175.9-171.2-1187.9110.5G103 G104 L120 M359 P360 I362 Y375 A376 W439G103-R373 PolarHBondContact O-NH1 3.05Å; G104-R373 PolarHBondContact O-NH1 3.39Å; L120-R373 PolarHBondContact O-NH2 2.88Å; M359-R373 WeakPolarHBondContact O-CD 3.38Å; M359-R373 PolarHBondContact O-NE 3.29Å; M359-R373 VanDerWaalsContact O-NE 3.13Å; M359-R373 PolarHBondContact SD-NH2 3.43Å; M359-R373 VanDerWaalsContact SD-NH2 3.36Å; P360-R373 PolarHBondContact O-N 3.01Å; I362-R373 HydrophobicContact CD1-CG 4.14Å; I362-R373 HydrophobicContact CG1-CG 4.4Å; I362-R373 HydrophobicContact CG2-CG 4.25Å; R373-Y375 VanDerWaalsContact C-N 3.28Å; R373-Y375 HydrophobicContact CB-CD1 3.8Å; R373-Y375 HydrophobicContact CB-CE1 3.74Å; R373-Y375 HydrophobicContact CG-CE1 4.41Å; R373-Y375 PolarHBondContact O-N 3.44Å; R373-Y375 VanDerWaalsContact O-N 3.15Å; R373-A376 WeakPolarHBondContact O-CB 3.45Å; R373-A376 PolarHBondContact O-N 3.44Å; R373-W439 CarbonylContact C-O 3.54Å; R373-W439 WeakPolarHBondContact CA-O 3.41Å
374R97.9Very high96.3Very high5 Ų555.9 Ų55.92%0.01929%0.293CS..THydrogen-bonded Turntrans-49.7-45.5-176.1177.559.3172.7-165.7-4.1113.8A376 R377 Y378 W439 E441 E468R374-A376 PolarHBondContact O-N 2.97Å; R374-A376 VanDerWaalsContact O-N 3.09Å; R374-R377 VanDerWaalsContact O-CB 3.29Å; R374-R377 WeakPolarHBondContact O-CB 3.49Å; R374-R377 PolarHBondContact O-N 2.94Å; R374-R377 VanDerWaalsContact O-N 3.08Å; R374-Y378 HydrophobicContact CG-CE2 4.38Å; R374-Y378 PolarHBondContact NE-OH 3.4Å; R374-Y378 PolarHBondContact NH2-OH 2.84Å; R374-W439 HydrophobicContact CB-CB 4.15Å; R374-W439 HydrophobicContact CB-CD2 3.62Å; R374-W439 HydrophobicContact CB-CE3 4.16Å; R374-W439 HydrophobicContact CB-CG 3.61Å; R374-W439 HydrophobicContact CG-CD2 3.66Å; R374-W439 VanDerWaalsContact CG-CE2 3.44Å; R374-W439 HydrophobicContact CG-CE3 4.07Å; R374-W439 HydrophobicContact CG-CG 4.14Å; R374-W439 HydrophobicContact CG-CH2 4.09Å; R374-W439 HydrophobicContact CG-CZ2 3.67Å; R374-W439 HydrophobicContact CG-CZ3 4.27Å; R374-W439 PolarHBondContact N-O 3.3Å; R374-E441 WeakPolarHBondContact CD-OE1 3.43Å; R374-E441 IonicContact CZ-OE1 3.32Å; R374-E441 IonicContact NE-OE1 3.3Å; R374-E441 IonicContact NH1-OE1 3.34Å; R374-E441 PolarHBondContact NH1-OE1 2.74Å; R374-E468 VanDerWaalsContact CZ-O 3.31Å; R374-E468 PolarHBondContact NH1-O 3.24Å; R374-E468 PolarHBondContact NH2-O 3.47Å
375Y98.3Very high96.4Very high1 Ų155.8 Ų55.80%0.00429%0.292CS..THydrogen-bonded Turntrans-62.9-21.5-175.479.9-92.5000113.2P212 D358 M359 P360 R373 R377 Y378 F379 L389P212-Y375 HydrophobicContact CB-CE1 4.46Å; P212-Y375 HydrophobicContact CG-CD1 3.85Å; P212-Y375 HydrophobicContact CG-CD2 4.11Å; P212-Y375 HydrophobicContact CG-CE1 3.71Å; P212-Y375 HydrophobicContact CG-CE2 4.03Å; P212-Y375 HydrophobicContact CG-CG 4.03Å; D358-Y375 WeakPolarHBondContact CA-OH 3.47Å; D358-Y375 VanDerWaalsContact OD1-CE2 3.31Å; D358-Y375 WeakPolarHBondContact OD1-CE2 3.37Å; D358-Y375 PolarHBondContact OD1-OH 2.81Å; M359-Y375 PolarHBondContact N-OH 3.13Å; P360-Y375 VanDerWaalsContact CA-OH 3.25Å; P360-Y375 WeakPolarHBondContact CA-OH 3.41Å; P360-Y375 HydrophobicContact CB-CE2 4.31Å; P360-Y375 WeakPolarHBondContact CD-OH 3.47Å; R373-Y375 VanDerWaalsContact C-N 3.28Å; R373-Y375 HydrophobicContact CB-CD1 3.8Å; R373-Y375 HydrophobicContact CB-CE1 3.74Å; R373-Y375 HydrophobicContact CG-CE1 4.41Å; R373-Y375 PolarHBondContact O-N 3.44Å; R373-Y375 VanDerWaalsContact O-N 3.15Å; Y375-R377 PolarHBondContact O-N 2.69Å; Y375-Y378 PolarHBondContact O-N 2.95Å; Y375-F379 HydrophobicContact CD2-CB 4.35Å; Y375-F379 PolarHBondContact O-N 2.85Å; Y375-F379 VanDerWaalsContact O-N 3.13Å; Y375-L389 HydrophobicContact CD2-CD1 4.5Å; Y375-L389 HydrophobicContact CD2-CD2 4.4Å; Y375-L389 HydrophobicContact CE2-CD1 4.16Å
376A97.9Very high96.6Very high10 Ų1053.6 Ų53.68%0.08327%0.27CS..Hα-helixtrans-60.9-25.4177.400000112.1P360 R373 R374 Y378 G380 D381P360-A376 HydrophobicContact CB-CB 3.79Å; R373-A376 WeakPolarHBondContact O-CB 3.45Å; R373-A376 PolarHBondContact O-N 3.44Å; R374-A376 PolarHBondContact O-N 2.97Å; R374-A376 VanDerWaalsContact O-N 3.09Å; A376-Y378 PolarHBondContact O-N 3.12Å; A376-G380 VanDerWaalsContact CA-O 3.3Å; A376-G380 WeakPolarHBondContact CA-O 3.24Å; A376-G380 WeakPolarHBondContact CB-O 3.17Å; A376-G380 CarbonylContact O-C 3.48Å; A376-G380 VanDerWaalsContact O-CA 3.26Å; A376-G380 WeakPolarHBondContact O-CA 3.22Å; A376-G380 PolarHBondContact O-N 3.4Å; A376-D381 HydrophobicContact CB-CB 4.41Å
377R97.1Very high96.8Very high104 Ų10453.4 Ų53.439%0.39227%0.268SS..Hα-helixtrans-56.6-33.3171.3-179.5178.8-76.1-161.11.5112.7R374 Y375 E441 K467 E468R374-R377 VanDerWaalsContact O-CB 3.29Å; R374-R377 WeakPolarHBondContact O-CB 3.49Å; R374-R377 PolarHBondContact O-N 2.94Å; R374-R377 VanDerWaalsContact O-N 3.08Å; Y375-R377 PolarHBondContact O-N 2.69Å; R377-E441 IonicContact CZ-OE1 3.33Å; R377-E441 IonicContact CZ-OE2 3.12Å; R377-E441 VanDerWaalsContact NE-CD 3.31Å; R377-E441 IonicContact NE-OE1 2.7Å; R377-E441 PolarHBondContact NE-OE1 3.21Å; R377-E441 IonicContact NE-OE2 3.09Å; R377-E441 PolarHBondContact NE-OE2 2.82Å; R377-E441 IonicContact NH2-OE1 2.99Å; R377-E441 PolarHBondContact NH2-OE1 3.31Å; R377-E441 IonicContact NH2-OE2 2.83Å; R377-E441 PolarHBondContact NH2-OE2 3.38Å; R377-K467 PolarHBondContact NH2-O 2.77Å; R377-K467 VanDerWaalsContact NH2-O 3.1Å; R377-E468 PolarHBondContact NH1-O 3.24Å; R377-E468 PolarHBondContact NH2-O 3.14Å
378Y97.9Very high97Very high74 Ų7453.3 Ų53.329%0.2926%0.26SS..Hα-helixtrans-101.7-29-173.5-46.8-74.1000112.9Y206 Q207 R374 Y375 A376Y206-Y378 PolarHBondContact O-OH 2.94Å; Q207-Y378 HydrophobicContact CB-CD1 4.48Å; Q207-Y378 HydrophobicContact CB-CD2 4.45Å; Q207-Y378 HydrophobicContact CB-CE1 3.98Å; Q207-Y378 HydrophobicContact CB-CE2 3.98Å; Q207-Y378 HydrophobicContact CG-CD1 3.83Å; Q207-Y378 HydrophobicContact CG-CD2 3.82Å; Q207-Y378 HydrophobicContact CG-CE1 3.85Å; Q207-Y378 HydrophobicContact CG-CE2 3.87Å; Q207-Y378 HydrophobicContact CG-CG 3.82Å; R374-Y378 HydrophobicContact CG-CE2 4.38Å; R374-Y378 PolarHBondContact NE-OH 3.4Å; R374-Y378 PolarHBondContact NH2-OH 2.84Å; Y375-Y378 PolarHBondContact O-N 2.95Å; A376-Y378 PolarHBondContact O-N 3.12Å
379F97.9Very high97.3Very high38 Ų3848.7 Ų48.717%0.16724%0.238CC..Hα-helixtrans-117.4-3.9-173.1-70.6-91.1000114.7L211 Y375 A385 L389 Y392L211-F379 HydrophobicContact CD1-CE2 4.38Å; L211-F379 HydrophobicContact CD2-CD2 3.92Å; L211-F379 HydrophobicContact CD2-CE2 3.42Å; L211-F379 VanDerWaalsContact CD2-CE2 3.42Å; L211-F379 HydrophobicContact CD2-CZ 4.33Å; Y375-F379 HydrophobicContact CD2-CB 4.35Å; Y375-F379 PolarHBondContact O-N 2.85Å; Y375-F379 VanDerWaalsContact O-N 3.13Å; F379-A385 HydrophobicContact CB-CB 3.88Å; F379-L389 HydrophobicContact CB-CD2 4.38Å; F379-L389 HydrophobicContact CD1-CD2 3.73Å; F379-L389 HydrophobicContact CD1-CG 3.87Å; F379-L389 HydrophobicContact CD2-CD2 3.67Å; F379-L389 HydrophobicContact CE1-CD2 3.87Å; F379-L389 HydrophobicContact CE1-CG 4.24Å; F379-L389 HydrophobicContact CE2-CD2 3.85Å; F379-L389 HydrophobicContact CG-CD2 3.64Å; F379-L389 HydrophobicContact CG-CG 4.06Å; F379-L389 HydrophobicContact CZ-CD2 3.94Å; F379-Y392 HydrophobicContact CE1-CG 4.28Å; F379-Y392 AromaticContact CZ-CD1 3.98Å; F379-Y392 HydrophobicContact CZ-CD1 3.98Å; F379-Y392 HydrophobicContact CZ-CD2 4.22Å; F379-Y392 AromaticContact CZ-CG 3.75Å; F379-Y392 HydrophobicContact CZ-CG 3.75Å
380G97.1Very high97.5Very high30 Ų3042.1 Ų42.131%0.30921%0.214SC..  trans92.9170.7-177.600000113.6A376A376-G380 VanDerWaalsContact CA-O 3.3Å; A376-G380 WeakPolarHBondContact CA-O 3.24Å; A376-G380 WeakPolarHBondContact CB-O 3.17Å; A376-G380 CarbonylContact O-C 3.48Å; A376-G380 VanDerWaalsContact O-CA 3.26Å; A376-G380 WeakPolarHBondContact O-CA 3.22Å; A376-G380 PolarHBondContact O-N 3.4Å
381D95.8Very high97.7Very high70 Ų7038.7 Ų38.737%0.37420%0.197SC..SBendtrans-1178.3-169.562-5.4000114.2R361 Y372 A376R361-D381 VanDerWaalsContact CD-O 3.24Å; R361-D381 WeakPolarHBondContact CD-O 3.32Å; Y372-D381 HydrophobicContact CD1-CB 3.7Å; Y372-D381 HydrophobicContact CE1-CB 3.76Å; A376-D381 HydrophobicContact CB-CB 4.41Å
382K96.7Very high97.8Very high165 Ų16539.8 Ų39.872%0.71720%0.201SC*.SBendtrans-84.7-14.2-171.5-67-179.7-177.8174.20114.9D384K382-D384 WeakPolarHBondContact CB-OD1 3.32Å
383G95.9Very high97.8Very high25 Ų2536.2 Ų36.226%0.25819%0.187SC..SBendtrans81.918.7-175.700000114.3D358D358-G383 WeakPolarHBondContact OD2-CA 3.16Å
384D97.3Very high97.8Very high103 Ų10336.1 Ų36.155%0.55119%0.187SC*.  trans-117.214.3179.362.6-1.1000113.5D358 K382 S386 P387D358-D384 PolarHBondContact OD2-N 3.03Å; K382-D384 WeakPolarHBondContact CB-OD1 3.32Å; D384-S386 PolarHBondContact O-N 2.87Å; D384-P387 WeakPolarHBondContact O-CD 3.47Å
385A98.1Very high97.8Very high3 Ų337.8 Ų37.83%0.02520%0.198CC..  trans-80.4-14.5-172.800000114.5D358 F379 S388 L389D358-A385 WeakPolarHBondContact OD2-CB 3.46Å; D358-A385 PolarHBondContact OD2-N 3.12Å; F379-A385 HydrophobicContact CB-CB 3.88Å; A385-S388 CarbonylContact O-C 3.28Å; A385-S388 WeakPolarHBondContact O-CA 3.26Å; A385-S388 PolarHBondContact O-N 2.94Å; A385-L389 HydrophobicContact CB-CD1 4Å; A385-L389 HydrophobicContact CB-CG 4.24Å; A385-L389 PolarHBondContact O-N 3.19Å
386S97.9Very high97.8Very high0 Ų041 Ų410%021%0.213CC..Hα-helixtrans-51.5-41.7-174.1-70.20000115.5T279 D358 D384 S390T279-S386 PolarHBondContact O-OG 2.77Å; D358-S386 VanDerWaalsContact CB-OG 3.25Å; D358-S386 WeakPolarHBondContact CB-OG 3.36Å; D384-S386 PolarHBondContact O-N 2.87Å; S386-S390 WeakPolarHBondContact O-CB 3.39Å; S386-S390 PolarHBondContact O-N 3.16Å; S386-S390 PolarHBondContact O-OG 3.19Å
387P98.5Very high97.9Very high24 Ų2440.8 Ų40.816%0.15621%0.21CC..Hα-helixtrans-59.8-45.4171.4-25.835.9000113.3F255 L257 L268 D384 S390 H391F255-P387 HydrophobicContact CD2-CB 3.8Å; F255-P387 HydrophobicContact CD2-CG 4.09Å; F255-P387 HydrophobicContact CE2-CB 3.87Å; F255-P387 HydrophobicContact CE2-CG 4.45Å; F255-P387 HydrophobicContact CG-CG 4.4Å; L257-P387 HydrophobicContact CD2-CB 4.04Å; L257-P387 WeakPolarHBondContact CD2-O 3.49Å; L268-P387 HydrophobicContact CD1-CG 4.03Å; L268-P387 HydrophobicContact CD2-CG 4.11Å; D384-P387 WeakPolarHBondContact O-CD 3.47Å; P387-S390 PolarHBondContact O-N 3.19Å; P387-S390 PolarHBondContact O-OG 2.97Å; P387-H391 WeakPolarHBondContact O-CB 3.49Å; P387-H391 PolarHBondContact O-N 3.46Å
388S98.5Very high97.9Very high48 Ų4841.5 Ų41.534%0.33622%0.215SC..Hα-helixtrans-70.4-37.8-179.8-65.10000112.3A385 Y392A385-S388 CarbonylContact O-C 3.28Å; A385-S388 WeakPolarHBondContact O-CA 3.26Å; A385-S388 PolarHBondContact O-N 2.94Å; S388-Y392 VanDerWaalsContact O-CB 3.31Å; S388-Y392 WeakPolarHBondContact O-CB 3.46Å; S388-Y392 PolarHBondContact O-N 3.02Å
389L98.6Very high97.9Very high3 Ų342.7 Ų42.72%0.01622%0.224CC..Hα-helixtrans-62.4-46174.6-77.8167.2000111.3L211 P212 A356 D358 Y375 F379 A385 Y392 A393L211-L389 HydrophobicContact CD2-CD2 4.27Å; P212-L389 HydrophobicContact CG-CD1 4Å; A356-L389 HydrophobicContact CB-CB 4.13Å; D358-L389 HydrophobicContact CB-CD1 4.34Å; Y375-L389 HydrophobicContact CD2-CD1 4.5Å; Y375-L389 HydrophobicContact CD2-CD2 4.4Å; Y375-L389 HydrophobicContact CE2-CD1 4.16Å; F379-L389 HydrophobicContact CB-CD2 4.38Å; F379-L389 HydrophobicContact CD1-CD2 3.73Å; F379-L389 HydrophobicContact CD1-CG 3.87Å; F379-L389 HydrophobicContact CD2-CD2 3.67Å; F379-L389 HydrophobicContact CE1-CD2 3.87Å; F379-L389 HydrophobicContact CE1-CG 4.24Å; F379-L389 HydrophobicContact CE2-CD2 3.85Å; F379-L389 HydrophobicContact CG-CD2 3.64Å; F379-L389 HydrophobicContact CG-CG 4.06Å; F379-L389 HydrophobicContact CZ-CD2 3.94Å; A385-L389 HydrophobicContact CB-CD1 4Å; A385-L389 HydrophobicContact CB-CG 4.24Å; A385-L389 PolarHBondContact O-N 3.19Å; L389-Y392 PolarHBondContact O-N 3.44Å; L389-A393 WeakPolarHBondContact O-CB 3.15Å; L389-A393 PolarHBondContact O-N 3.14Å
390S98.6Very high98Very high0 Ų041 Ų410%022%0.216CC..Hα-helixtrans-68.3-39.6178.959.20000112.6S386 P387 A393 L394S386-S390 WeakPolarHBondContact O-CB 3.39Å; S386-S390 PolarHBondContact O-N 3.16Å; S386-S390 PolarHBondContact O-OG 3.19Å; P387-S390 PolarHBondContact O-N 3.19Å; P387-S390 PolarHBondContact O-OG 2.97Å; S390-A393 PolarHBondContact O-N 2.85Å; S390-L394 WeakPolarHBondContact O-CB 3.32Å; S390-L394 WeakPolarHBondContact O-CG 3.46Å; S390-L394 PolarHBondContact O-N 3Å
391H98.8Very high98Very high7 Ų740.5 Ų40.53%0.03221%0.206CC..Hα-helixtrans-58.8-49.3170.9177.8-82.3000111.9L257 K259 E262 V264 P387 A393 L394 T395L257-H391 HydrophobicContact CD2-CB 3.83Å; K259-H391 PolarHBondContact O-CE1 3.34Å; K259-H391 PolarHBondContact O-NE2 3.41Å; E262-H391 PolarHBondContact O-NE2 3.18Å; V264-H391 HydrophobicContact CG2-CB 4.31Å; P387-H391 WeakPolarHBondContact O-CB 3.49Å; P387-H391 PolarHBondContact O-N 3.46Å; H391-A393 PolarHBondContact O-N 3.16Å; H391-L394 PolarHBondContact O-N 3.09Å; H391-T395 WeakPolarHBondContact O-CB 3.49Å; H391-T395 WeakPolarHBondContact O-CG2 3.49Å; H391-T395 PolarHBondContact O-N 3.09Å; H391-T395 VanDerWaalsContact O-N 3.08Å; H391-T395 PolarHBondContact O-OG1 3.24Å
392Y98.7Very high98.1Very high47 Ų4742.2 Ų42.218%0.18421%0.21CC..Hα-helixtrans-59.6-48.5178.2-169.8-95.4000111.5D208 L211 F379 S388 L389 L394 T395 H396 W400D208-Y392 WeakPolarHBondContact OD1-CE1 3.33Å; D208-Y392 PolarHBondContact OD1-OH 3.43Å; L211-Y392 HydrophobicContact CD1-CD1 3.81Å; L211-Y392 HydrophobicContact CD1-CE1 3.83Å; F379-Y392 HydrophobicContact CE1-CG 4.28Å; F379-Y392 AromaticContact CZ-CD1 3.98Å; F379-Y392 HydrophobicContact CZ-CD1 3.98Å; F379-Y392 HydrophobicContact CZ-CD2 4.22Å; F379-Y392 AromaticContact CZ-CG 3.75Å; F379-Y392 HydrophobicContact CZ-CG 3.75Å; S388-Y392 VanDerWaalsContact O-CB 3.31Å; S388-Y392 WeakPolarHBondContact O-CB 3.46Å; S388-Y392 PolarHBondContact O-N 3.02Å; L389-Y392 PolarHBondContact O-N 3.44Å; Y392-L394 PolarHBondContact O-N 3.03Å; Y392-T395 PolarHBondContact O-N 3Å; Y392-T395 PolarHBondContact O-OG1 3.3Å; Y392-T395 VanDerWaalsContact O-OG1 3.07Å; Y392-H396 HydrophobicContact CD1-CB 4.48Å; Y392-H396 AromaticContact CD2-CE1 3.6Å; Y392-H396 AromaticContact CD2-ND1 3.66Å; Y392-H396 HydrophobicContact CE1-CB 4.23Å; Y392-H396 AromaticContact CE2-CD2 3.79Å; Y392-H396 AromaticContact CE2-CE1 3.5Å; Y392-H396 VanDerWaalsContact CE2-CE1 3.5Å; Y392-H396 WeakPolarHBondContact CE2-CE1 3.28Å; Y392-H396 AromaticContact CE2-CG 3.93Å; Y392-H396 AromaticContact CE2-ND1 3.74Å; Y392-H396 AromaticContact CE2-NE2 3.53Å; Y392-H396 AromaticContact CG-ND1 3.95Å; Y392-H396 AromaticContact CZ-CD2 3.72Å; Y392-H396 AromaticContact CZ-CG 3.84Å; Y392-H396 AromaticContact CZ-NE2 3.96Å; Y392-H396 VanDerWaalsContact O-CB 3.29Å; Y392-H396 WeakPolarHBondContact O-CB 3.46Å; Y392-H396 PolarHBondContact O-N 3.18Å; Y392-H396 PolarHBondContact O-ND1 3.12Å; Y392-W400 HydrophobicContact CD1-CZ2 4.08Å; Y392-W400 HydrophobicContact CE1-CZ2 4.09Å
393A98.7Very high98.2Very high1 Ų135.6 Ų35.61%0.00819%0.185CC..Hα-helixtrans-59.4-48.5179.500000112.6A213 V215 L389 S390 H391 T395 H396 Y397 W400A213-A393 HydrophobicContact CB-CB 4.26Å; V215-A393 HydrophobicContact CG2-CB 3.89Å; L389-A393 WeakPolarHBondContact O-CB 3.15Å; L389-A393 PolarHBondContact O-N 3.14Å; S390-A393 PolarHBondContact O-N 2.85Å; H391-A393 PolarHBondContact O-N 3.16Å; A393-T395 VanDerWaalsContact C-N 3.25Å; A393-T395 PolarHBondContact O-N 2.83Å; A393-H396 PolarHBondContact O-N 3.43Å; A393-Y397 WeakPolarHBondContact O-CB 3.31Å; A393-Y397 PolarHBondContact O-N 3.24Å; A393-W400 VanDerWaalsContact CA-CH2 3.47Å; A393-W400 HydrophobicContact CB-CH2 3.58Å; A393-W400 HydrophobicContact CB-CZ3 4.04Å
394L98.5Very high98.3Very high0 Ų034.4 Ų34.40%017%0.173CC..Hα-helixtrans-68.6-22.6-178.9-72.7166.8000113.6V264 A283 R285 E352 C354 S390 H391 Y392V264-L394 HydrophobicContact CB-CD1 4.41Å; V264-L394 HydrophobicContact CG1-CD1 3.67Å; V264-L394 HydrophobicContact CG2-CB 4.33Å; V264-L394 HydrophobicContact CG2-CD1 3.79Å; A283-L394 HydrophobicContact CB-CD1 4.32Å; R285-L394 HydrophobicContact CB-CD1 4.42Å; E352-L394 HydrophobicContact CB-CD2 3.99Å; C354-L394 HydrophobicContact CB-CD1 3.98Å; C354-L394 HydrophobicContact CB-CD2 4Å; C354-L394 HydrophobicContact CB-CG 3.76Å; S390-L394 WeakPolarHBondContact O-CB 3.32Å; S390-L394 WeakPolarHBondContact O-CG 3.46Å; S390-L394 PolarHBondContact O-N 3Å; H391-L394 PolarHBondContact O-N 3.09Å; Y392-L394 PolarHBondContact O-N 3.03Å
395T97.9Very high98.4Very high40 Ų4033.4 Ų33.425%0.24516%0.164CC..Hα-helixtrans-93.4-20.6177.953.20000113.3E262 H391 Y392 A393E262-T395 HydrophobicContact CB-CG2 3.94Å; E262-T395 HydrophobicContact CG-CG2 4.1Å; H391-T395 WeakPolarHBondContact O-CB 3.49Å; H391-T395 WeakPolarHBondContact O-CG2 3.49Å; H391-T395 PolarHBondContact O-N 3.09Å; H391-T395 VanDerWaalsContact O-N 3.08Å; H391-T395 PolarHBondContact O-OG1 3.24Å; Y392-T395 PolarHBondContact O-N 3Å; Y392-T395 PolarHBondContact O-OG1 3.3Å; Y392-T395 VanDerWaalsContact O-OG1 3.07Å; A393-T395 VanDerWaalsContact C-N 3.25Å; A393-T395 PolarHBondContact O-N 2.83Å
396H98Very high98.4Very high69 Ų6937.7 Ų37.732%0.31918%0.184SC..Hα-helixtrans-113.7-13.4-173.9-65.470.2000115Y392 A393 K398 Q399 W400Y392-H396 HydrophobicContact CD1-CB 4.48Å; Y392-H396 AromaticContact CD2-CE1 3.6Å; Y392-H396 AromaticContact CD2-ND1 3.66Å; Y392-H396 HydrophobicContact CE1-CB 4.23Å; Y392-H396 AromaticContact CE2-CD2 3.79Å; Y392-H396 AromaticContact CE2-CE1 3.5Å; Y392-H396 VanDerWaalsContact CE2-CE1 3.5Å; Y392-H396 WeakPolarHBondContact CE2-CE1 3.28Å; Y392-H396 AromaticContact CE2-CG 3.93Å; Y392-H396 AromaticContact CE2-ND1 3.74Å; Y392-H396 AromaticContact CE2-NE2 3.53Å; Y392-H396 AromaticContact CG-ND1 3.95Å; Y392-H396 AromaticContact CZ-CD2 3.72Å; Y392-H396 AromaticContact CZ-CG 3.84Å; Y392-H396 AromaticContact CZ-NE2 3.96Å; Y392-H396 VanDerWaalsContact O-CB 3.29Å; Y392-H396 WeakPolarHBondContact O-CB 3.46Å; Y392-H396 PolarHBondContact O-N 3.18Å; Y392-H396 PolarHBondContact O-ND1 3.12Å; A393-H396 PolarHBondContact O-N 3.43Å; H396-K398 PolarHBondContact O-N 3.44Å; H396-Q399 WeakPolarHBondContact O-CA 3.21Å; H396-Q399 WeakPolarHBondContact O-CB 3.48Å; H396-Q399 PolarHBondContact O-N 3.4Å; H396-W400 HydrophobicContact CB-CZ2 4.42Å; H396-W400 PolarHBondContact O-N 3.35Å; H396-W400 VanDerWaalsContact O-N 3.15Å
397Y98.4Very high98.4Very high5 Ų540 Ų402%0.0219%0.193CC..Hα-helixtrans-56.5-30.5-17481.8-90.2000114.7I198 V215 V217 E352 A393 Q399 W400 E401I198-Y397 HydrophobicContact CD1-CD2 4.49Å; V215-Y397 HydrophobicContact CB-CG 4.35Å; V215-Y397 HydrophobicContact CG1-CD1 4.01Å; V215-Y397 HydrophobicContact CG1-CD2 4.23Å; V215-Y397 HydrophobicContact CG1-CE1 4.47Å; V215-Y397 HydrophobicContact CG1-CG 3.86Å; V215-Y397 HydrophobicContact CG2-CG 4.4Å; V217-Y397 HydrophobicContact CG2-CD2 4.1Å; V217-Y397 HydrophobicContact CG2-CE2 3.47Å; V217-Y397 VanDerWaalsContact CG2-CE2 3.47Å; E352-Y397 HydrophobicContact CG-CE1 4.29Å; E352-Y397 PolarHBondContact OE1-OH 3.38Å; A393-Y397 WeakPolarHBondContact O-CB 3.31Å; A393-Y397 PolarHBondContact O-N 3.24Å; Y397-Q399 VanDerWaalsContact C-N 3.28Å; Y397-Q399 PolarHBondContact O-N 3.01Å; Y397-W400 WeakPolarHBondContact O-CA 3.31Å; Y397-W400 WeakPolarHBondContact O-CB 3.43Å; Y397-W400 PolarHBondContact O-N 3.29Å; Y397-W400 VanDerWaalsContact O-N 3.14Å; Y397-E401 HydrophobicContact CD2-CG 4.48Å; Y397-E401 PolarHBondContact O-N 3.47Å
398K98.1Very high98.4Very high119 Ų11938.8 Ų38.852%0.51719%0.185SC..Hα-helixtrans-64.7-35.4176.4-65.6-177.6-177.1173.20111.6E352 H396 K402E352-K398 IonicContact OE1-NZ 3.69Å; H396-K398 PolarHBondContact O-N 3.44Å; K398-K402 WeakPolarHBondContact O-CB 3.47Å; K398-K402 PolarHBondContact O-N 3.43Å
399Q98.5Very high98.3Very high100 Ų10041.9 Ų41.947%0.46719%0.189SC..Hα-helixtrans-71.2-36.1173-178.356.437.100110.9H396 Y397 K402 S403H396-Q399 WeakPolarHBondContact O-CA 3.21Å; H396-Q399 WeakPolarHBondContact O-CB 3.48Å; H396-Q399 PolarHBondContact O-N 3.4Å; Y397-Q399 VanDerWaalsContact C-N 3.28Å; Y397-Q399 PolarHBondContact O-N 3.01Å; Q399-K402 PolarHBondContact O-N 3.11Å; Q399-S403 PolarHBondContact NE2-OG 2.94Å; Q399-S403 WeakPolarHBondContact O-CB 3.25Å; Q399-S403 PolarHBondContact O-N 3.32Å; Q399-S403 PolarHBondContact O-OG 3Å
400W98.5Very high98.3Very high2 Ų246 Ų461%0.00822%0.216CC..Hα-helixtrans-59.8-51171.2-54.7-21.3000111I198 P200 I202 D208 L211 V215 Y392 A393 H396 Y397 K402 S403 I404I198-W400 HydrophobicContact CG2-CE3 4.49Å; P200-W400 HydrophobicContact CB-CD2 3.81Å; P200-W400 HydrophobicContact CB-CE3 3.78Å; P200-W400 HydrophobicContact CB-CG 4.45Å; P200-W400 HydrophobicContact CB-CH2 3.94Å; P200-W400 HydrophobicContact CB-CZ2 3.99Å; P200-W400 HydrophobicContact CB-CZ3 3.85Å; P200-W400 HydrophobicContact CG-CH2 4.25Å; P200-W400 HydrophobicContact CG-CZ3 4.26Å; I202-W400 HydrophobicContact CD1-CB 4.06Å; I202-W400 HydrophobicContact CD1-CG 4.19Å; D208-W400 VanDerWaalsContact OD2-CD1 3.31Å; D208-W400 PolarHBondContact OD2-NE1 3.09Å; L211-W400 HydrophobicContact CD1-CH2 4.45Å; L211-W400 HydrophobicContact CD1-CZ2 3.97Å; V215-W400 HydrophobicContact CG2-CZ3 4.22Å; Y392-W400 HydrophobicContact CD1-CZ2 4.08Å; Y392-W400 HydrophobicContact CE1-CZ2 4.09Å; A393-W400 VanDerWaalsContact CA-CH2 3.47Å; A393-W400 HydrophobicContact CB-CH2 3.58Å; A393-W400 HydrophobicContact CB-CZ3 4.04Å; H396-W400 HydrophobicContact CB-CZ2 4.42Å; H396-W400 PolarHBondContact O-N 3.35Å; H396-W400 VanDerWaalsContact O-N 3.15Å; Y397-W400 WeakPolarHBondContact O-CA 3.31Å; Y397-W400 WeakPolarHBondContact O-CB 3.43Å; Y397-W400 PolarHBondContact O-N 3.29Å; Y397-W400 VanDerWaalsContact O-N 3.14Å; W400-K402 VanDerWaalsContact C-N 3.33Å; W400-K402 PolarHBondContact O-N 3.27Å; W400-S403 PolarHBondContact O-N 3.04Å; W400-S403 VanDerWaalsContact O-N 3.16Å; W400-I404 HydrophobicContact CB-CD1 4.37Å; W400-I404 WeakPolarHBondContact O-CB 3.25Å; W400-I404 WeakPolarHBondContact O-CD1 3.31Å; W400-I404 WeakPolarHBondContact O-CG1 3.41Å; W400-I404 PolarHBondContact O-N 2.72Å
401E98.1Very high98.2Very high20 Ų2046.9 Ų46.99%0.09322%0.221CC..Hα-helixtrans-56.5-46.7178-74.8-167.6113.200111.7R196 I198 Y397 S403 I404 E405R196-E401 IonicContact CZ-OE1 3.76Å; R196-E401 VanDerWaalsContact NH1-CD 3.29Å; R196-E401 IonicContact NH1-OE1 3.49Å; R196-E401 PolarHBondContact NH1-OE1 3.04Å; R196-E401 IonicContact NH1-OE2 3.85Å; R196-E401 PolarHBondContact NH1-OE2 3.1Å; I198-E401 HydrophobicContact CG1-CG 3.99Å; I198-E401 HydrophobicContact CG2-CG 4.28Å; Y397-E401 HydrophobicContact CD2-CG 4.48Å; Y397-E401 PolarHBondContact O-N 3.47Å; E401-S403 PolarHBondContact O-N 3.02Å; E401-I404 PolarHBondContact O-N 3.24Å; E401-E405 WeakPolarHBondContact O-CB 3.35Å; E401-E405 VanDerWaalsContact O-CG 3.31Å; E401-E405 WeakPolarHBondContact O-CG 3.17Å; E401-E405 PolarHBondContact O-N 3.32Å
402K98.4Very high98.2Very high105 Ų10548.3 Ų48.346%0.45723%0.228SC..Hα-helixtrans-57.3-49.1176.4179.6179.9170.8-173.90111.5K398 Q399 W400 I404 E405 E406K398-K402 WeakPolarHBondContact O-CB 3.47Å; K398-K402 PolarHBondContact O-N 3.43Å; Q399-K402 PolarHBondContact O-N 3.11Å; W400-K402 VanDerWaalsContact C-N 3.33Å; W400-K402 PolarHBondContact O-N 3.27Å; K402-I404 VanDerWaalsContact C-N 3.33Å; K402-I404 PolarHBondContact O-N 3.4Å; K402-E405 PolarHBondContact O-N 2.9Å; K402-E406 WeakPolarHBondContact CE-OE1 3.38Å; K402-E406 HydrophobicContact CG-CG 4.49Å; K402-E406 WeakPolarHBondContact CG-OE1 3.46Å; K402-E406 IonicContact NZ-OE1 3.97Å; K402-E406 WeakPolarHBondContact O-CB 2.97Å; K402-E406 VanDerWaalsContact O-CG 3.27Å; K402-E406 WeakPolarHBondContact O-CG 3.45Å; K402-E406 PolarHBondContact O-N 3.22Å
403S98.6Very high98Very high27 Ų2752.5 Ų52.519%0.18925%0.25CC..Hα-helixtrans-63.8-41.8-179.8-50.70000110.8Q399 W400 E401 E405 E406 W407Q399-S403 PolarHBondContact NE2-OG 2.94Å; Q399-S403 WeakPolarHBondContact O-CB 3.25Å; Q399-S403 PolarHBondContact O-N 3.32Å; Q399-S403 PolarHBondContact O-OG 3Å; W400-S403 PolarHBondContact O-N 3.04Å; W400-S403 VanDerWaalsContact O-N 3.16Å; E401-S403 PolarHBondContact O-N 3.02Å; S403-E405 PolarHBondContact O-N 2.99Å; S403-E406 PolarHBondContact O-N 2.83Å; S403-W407 PolarHBondContact O-N 3.09Å; S403-W407 VanDerWaalsContact O-N 3.15Å
404I98.6Very high97.9Very high0 Ų054.3 Ų54.30%026%0.259CS..Hα-helixtrans-59.1-48.1175.9-68.8159.5000110.8P178 R179 I198 I202 W400 E401 K402 W407 Q408P178-I404 HydrophobicContact CG-CD1 3.64Å; P178-I404 HydrophobicContact CG-CG1 3.87Å; P178-I404 HydrophobicContact CG-CG2 4.01Å; R179-I404 HydrophobicContact CG-CD1 4.38Å; R179-I404 HydrophobicContact CG-CG2 4.46Å; I198-I404 HydrophobicContact CG2-CD1 4.21Å; I202-I404 HydrophobicContact CG1-CG1 4.02Å; W400-I404 HydrophobicContact CB-CD1 4.37Å; W400-I404 WeakPolarHBondContact O-CB 3.25Å; W400-I404 WeakPolarHBondContact O-CD1 3.31Å; W400-I404 WeakPolarHBondContact O-CG1 3.41Å; W400-I404 PolarHBondContact O-N 2.72Å; E401-I404 PolarHBondContact O-N 3.24Å; K402-I404 VanDerWaalsContact C-N 3.33Å; K402-I404 PolarHBondContact O-N 3.4Å; I404-W407 PolarHBondContact O-NE1 2.92Å; I404-Q408 HydrophobicContact CG2-CG 4.48Å; I404-Q408 WeakPolarHBondContact O-CB 3.41Å; I404-Q408 VanDerWaalsContact O-CG 3.24Å; I404-Q408 WeakPolarHBondContact O-CG 3.26Å; I404-Q408 PolarHBondContact O-N 3.48Å; I404-Q408 VanDerWaalsContact O-N 3.16Å
405E97.9Very high97.7Very high81 Ų8160 Ų6038%0.37930%0.299SS..Hα-helixtrans-65.4-40.1178.3-73.9175.9-178.100112.4R179 E401 K402 S403 Q408 R409R179-E405 IonicContact CZ-OE1 2.7Å; R179-E405 VanDerWaalsContact NH1-CG 3.34Å; R179-E405 IonicContact NH1-OE1 2.82Å; R179-E405 PolarHBondContact NH1-OE1 2.59Å; R179-E405 VanDerWaalsContact NH2-CG 3.34Å; E401-E405 WeakPolarHBondContact O-CB 3.35Å; E401-E405 VanDerWaalsContact O-CG 3.31Å; E401-E405 WeakPolarHBondContact O-CG 3.17Å; E401-E405 PolarHBondContact O-N 3.32Å; K402-E405 PolarHBondContact O-N 2.9Å; S403-E405 PolarHBondContact O-N 2.99Å; E405-Q408 PolarHBondContact O-N 2.96Å; E405-R409 WeakPolarHBondContact O-CB 3.26Å; E405-R409 PolarHBondContact O-N 2.65Å
406E98.1Very high97.5Very high94 Ų9461.4 Ų61.444%0.43931%0.311SS..Hα-helixtrans-60.8-44.8180-78.5172176.400112.1K402 S403 P410K402-E406 WeakPolarHBondContact CE-OE1 3.38Å; K402-E406 HydrophobicContact CG-CG 4.49Å; K402-E406 WeakPolarHBondContact CG-OE1 3.46Å; K402-E406 IonicContact NZ-OE1 3.97Å; K402-E406 WeakPolarHBondContact O-CB 2.97Å; K402-E406 VanDerWaalsContact O-CG 3.27Å; K402-E406 WeakPolarHBondContact O-CG 3.45Å; K402-E406 PolarHBondContact O-N 3.22Å; S403-E406 PolarHBondContact O-N 2.83Å; E406-P410 WeakPolarHBondContact O-CD 3.46Å
407W97.5Very high97.3Very high47 Ų4758.5 Ų58.518%0.17830%0.298CS..Hα-helixtrans-76.1-31.8179.881.8-99.7000113.1P203 S403 I404 P410 F426 L429 L499 W833P203-W407 HydrophobicContact CG-CD2 3.66Å; P203-W407 HydrophobicContact CG-CE3 3.8Å; P203-W407 HydrophobicContact CG-CG 3.99Å; P203-W407 HydrophobicContact CG-CH2 4.3Å; P203-W407 HydrophobicContact CG-CZ2 4.24Å; P203-W407 HydrophobicContact CG-CZ3 4.05Å; S403-W407 PolarHBondContact O-N 3.09Å; S403-W407 VanDerWaalsContact O-N 3.15Å; I404-W407 PolarHBondContact O-NE1 2.92Å; W407-P410 WeakPolarHBondContact O-CD 3.48Å; W407-F426 AromaticContact CE3-CE1 3.97Å; W407-F426 HydrophobicContact CE3-CE1 3.97Å; W407-F426 AromaticContact CH2-CD1 3.37Å; W407-F426 HydrophobicContact CH2-CD1 3.37Å; W407-F426 AromaticContact CH2-CE1 3.45Å; W407-F426 HydrophobicContact CH2-CE1 3.45Å; W407-F426 VanDerWaalsContact CH2-CE1 3.45Å; W407-F426 HydrophobicContact CZ2-CD1 4.1Å; W407-F426 HydrophobicContact CZ2-CE1 4.22Å; W407-F426 AromaticContact CZ3-CD1 3.75Å; W407-F426 HydrophobicContact CZ3-CD1 3.75Å; W407-F426 AromaticContact CZ3-CE1 3.32Å; W407-F426 HydrophobicContact CZ3-CE1 3.32Å; W407-L429 HydrophobicContact CH2-CD1 3.7Å; W407-L429 HydrophobicContact CZ3-CD1 4.45Å; W407-L499 HydrophobicContact CZ3-CD2 4.25Å; W407-W833 HydrophobicContact CH2-CZ2 4.42Å; W407-W833 AromaticContact CZ3-CH2 3.81Å; W407-W833 HydrophobicContact CZ3-CH2 3.81Å; W407-W833 HydrophobicContact CZ3-CZ2 4.03Å
408Q98.4Very high97.2Very high0 Ų059.1 Ų59.10%030%0.302CS..Hα-helixtrans-75.1-32177.6-67.8-177.6-31.500112.4Y177 R179 I404 E405 I411 L412 F426Y177-Q408 PolarHBondContact O-NE2 3.49Å; R179-Q408 VanDerWaalsContact NH2-OE1 3.11Å; I404-Q408 HydrophobicContact CG2-CG 4.48Å; I404-Q408 WeakPolarHBondContact O-CB 3.41Å; I404-Q408 VanDerWaalsContact O-CG 3.24Å; I404-Q408 WeakPolarHBondContact O-CG 3.26Å; I404-Q408 PolarHBondContact O-N 3.48Å; I404-Q408 VanDerWaalsContact O-N 3.16Å; E405-Q408 PolarHBondContact O-N 2.96Å; Q408-I411 PolarHBondContact O-N 2.91Å; Q408-L412 HydrophobicContact CB-CD1 3.71Å; Q408-L412 HydrophobicContact CB-CG 4.17Å; Q408-L412 WeakPolarHBondContact O-CG 3.2Å; Q408-L412 PolarHBondContact O-N 3.2Å; Q408-F426 HydrophobicContact CB-CE1 4.14Å; Q408-F426 HydrophobicContact CB-CE2 4.41Å; Q408-F426 HydrophobicContact CB-CZ 3.86Å; Q408-F426 HydrophobicContact CG-CD1 4.04Å; Q408-F426 HydrophobicContact CG-CE1 3.65Å; Q408-F426 HydrophobicContact CG-CE2 4.49Å; Q408-F426 HydrophobicContact CG-CZ 3.89Å
409R97.9Very high97Very high112 Ų11256.5 Ų56.542%0.42330%0.297SS..Hα-helixtrans-52.5-46.7-169.8178.7-172.1-46.1-125.6-2.8114.9E405 I411 L412 Q413E405-R409 WeakPolarHBondContact O-CB 3.26Å; E405-R409 PolarHBondContact O-N 2.65Å; R409-I411 VanDerWaalsContact C-N 3.3Å; R409-I411 PolarHBondContact O-N 2.84Å; R409-L412 PolarHBondContact O-N 3.41Å; R409-Q413 HydrophobicContact CG-CG 3.95Å; R409-Q413 VanDerWaalsContact O-CB 3.32Å; R409-Q413 WeakPolarHBondContact O-CB 3.39Å; R409-Q413 WeakPolarHBondContact O-CG 3.41Å; R409-Q413 PolarHBondContact O-N 2.69Å
410P97.4Very high96.9Very high89 Ų8952.4 Ų52.458%0.57828%0.277SS*.Hα-helixtrans-57-43.7-177.8-25.935.7000112.6E406 W407 D414E406-P410 WeakPolarHBondContact O-CD 3.46Å; W407-P410 WeakPolarHBondContact O-CD 3.48Å; P410-D414 PolarHBondContact O-N 3.21Å
411I97.7Very high96.9Very high20 Ų2052.3 Ų52.310%0.10328%0.277CS..Hα-helixtrans-73.3-43.2179.1-64.9160.8000110.7Q408 R409 Q413 D414 L417 K422 L425 F426 W833 Q836Q408-I411 PolarHBondContact O-N 2.91Å; R409-I411 VanDerWaalsContact C-N 3.3Å; R409-I411 PolarHBondContact O-N 2.84Å; I411-Q413 VanDerWaalsContact C-N 3.3Å; I411-Q413 PolarHBondContact O-N 3.34Å; I411-D414 PolarHBondContact O-N 3.35Å; I411-L417 HydrophobicContact CG2-CD1 3.93Å; I411-K422 HydrophobicContact CG2-CG 4.41Å; I411-K422 VanDerWaalsContact O-CE 3.25Å; I411-K422 WeakPolarHBondContact O-CE 3.45Å; I411-L425 HydrophobicContact CD1-CD2 3.86Å; I411-L425 HydrophobicContact CG2-CD2 3.97Å; I411-F426 HydrophobicContact CB-CE2 4.33Å; I411-F426 HydrophobicContact CB-CZ 3.94Å; I411-F426 HydrophobicContact CD1-CE1 4.33Å; I411-F426 HydrophobicContact CD1-CZ 3.94Å; I411-F426 HydrophobicContact CG2-CE2 3.98Å; I411-F426 HydrophobicContact CG2-CZ 4Å; I411-W833 HydrophobicContact CD1-CH2 4.44Å; I411-Q836 HydrophobicContact CD1-CG 4.37Å
412L97.4Very high96.8Very high36 Ų3651.7 Ų51.719%0.18827%0.274CS..Hα-helixtrans-64.4-35.3-179.1-67.9179.3000112.7E29 L176 Q408 R409 K422 F426E29-L412 HydrophobicContact CB-CD2 3.85Å; E29-L412 HydrophobicContact CG-CD2 4.15Å; L176-L412 HydrophobicContact CD1-CD2 4.44Å; L176-L412 HydrophobicContact CD2-CD1 3.86Å; L176-L412 HydrophobicContact CD2-CD2 4.2Å; Q408-L412 HydrophobicContact CB-CD1 3.71Å; Q408-L412 HydrophobicContact CB-CG 4.17Å; Q408-L412 WeakPolarHBondContact O-CG 3.2Å; Q408-L412 PolarHBondContact O-N 3.2Å; R409-L412 PolarHBondContact O-N 3.41Å; L412-K422 HydrophobicContact CD2-CB 4.2Å; L412-K422 HydrophobicContact CD2-CD 4.35Å; L412-K422 PolarHBondContact O-NZ 3.11Å; L412-F426 HydrophobicContact CD2-CD2 4.07Å; L412-F426 HydrophobicContact CD2-CE2 3.56Å; L412-F426 HydrophobicContact CG-CE2 3.88Å; L412-F426 HydrophobicContact CG-CZ 4.46Å
413Q96.3Very high96.8Very high135 Ų13546.7 Ų46.763%0.63125%0.253SS*.Hα-helixtrans-83.1-14.8180-68.9-175.4-2100113.6R409 I411 S415R409-Q413 HydrophobicContact CG-CG 3.95Å; R409-Q413 VanDerWaalsContact O-CB 3.32Å; R409-Q413 WeakPolarHBondContact O-CB 3.39Å; R409-Q413 WeakPolarHBondContact O-CG 3.41Å; R409-Q413 PolarHBondContact O-N 2.69Å; I411-Q413 VanDerWaalsContact C-N 3.3Å; I411-Q413 PolarHBondContact O-N 3.34Å; Q413-S415 PolarHBondContact O-N 2.9Å
414D95.4Very high96.8Very high39 Ų3945.4 Ų45.421%0.20924%0.244CC..  trans-67.1106.8174.7-171.1-18000110.2P410 I411 S416 L417 K422P410-D414 PolarHBondContact O-N 3.21Å; I411-D414 PolarHBondContact O-N 3.35Å; D414-S416 VanDerWaalsContact CG-OG 3.25Å; D414-S416 PolarHBondContact O-N 2.99Å; D414-S416 WeakPolarHBondContact OD1-CA 3.48Å; D414-S416 VanDerWaalsContact OD1-CB 3.22Å; D414-S416 WeakPolarHBondContact OD1-CB 3.31Å; D414-S416 PolarHBondContact OD1-N 2.78Å; D414-S416 PolarHBondContact OD1-OG 3.23Å; D414-S416 PolarHBondContact OD2-OG 3.38Å; D414-L417 HydrophobicContact CB-CD1 3.98Å; D414-L417 HydrophobicContact CB-CG 4.06Å; D414-L417 PolarHBondContact O-N 3.17Å; D414-K422 VanDerWaalsContact O-CE 3.27Å; D414-K422 WeakPolarHBondContact O-CE 3.45Å; D414-K422 PolarHBondContact O-NZ 3.25Å
415S94.4Very high96.8Very high120 Ų12045.4 Ų45.484%0.83924%0.244SC*.THydrogen-bonded Turntrans-73.1-13.6179.757.60000113.6Q413 L417Q413-S415 PolarHBondContact O-N 2.9Å; S415-L417 VanDerWaalsContact C-N 3.27Å
416S93Very high96.8Very high70 Ų7041.6 Ų41.649%0.4923%0.225SC..THydrogen-bonded Turntrans-74.8-21.4174.677.60000112.2D414D414-S416 VanDerWaalsContact CG-OG 3.25Å; D414-S416 PolarHBondContact O-N 2.99Å; D414-S416 WeakPolarHBondContact OD1-CA 3.48Å; D414-S416 VanDerWaalsContact OD1-CB 3.22Å; D414-S416 WeakPolarHBondContact OD1-CB 3.31Å; D414-S416 PolarHBondContact OD1-N 2.78Å; D414-S416 PolarHBondContact OD1-OG 3.23Å; D414-S416 PolarHBondContact OD2-OG 3.38Å
417L95.5Very high96.9Very high8 Ų837.1 Ų37.14%0.04221%0.205CC..SBendtrans-89.2130.5179.2-60.7-179.1000111.4I411 D414 S415 Y421 K422 M791 L839I411-L417 HydrophobicContact CG2-CD1 3.93Å; D414-L417 HydrophobicContact CB-CD1 3.98Å; D414-L417 HydrophobicContact CB-CG 4.06Å; D414-L417 PolarHBondContact O-N 3.17Å; S415-L417 VanDerWaalsContact C-N 3.27Å; L417-Y421 HydrophobicContact CB-CD1 4.28Å; L417-Y421 HydrophobicContact CD1-CD1 4.25Å; L417-Y421 HydrophobicContact CD1-CE1 4.1Å; L417-Y421 HydrophobicContact CD2-CD1 4.15Å; L417-Y421 HydrophobicContact CD2-CE1 4.18Å; L417-Y421 HydrophobicContact CG-CD1 4.47Å; L417-K422 HydrophobicContact CB-CG 4.44Å; L417-K422 VanDerWaalsContact O-CE 3.24Å; L417-K422 WeakPolarHBondContact O-CE 3.44Å; L417-K422 PolarHBondContact O-NZ 3.28Å; L417-M791 HydrophobicContact CD2-CE 4.18Å; L417-L839 HydrophobicContact CD2-CD1 3.86Å
418P95.1Very high96.9Very high17 Ų1734.9 Ų34.911%0.1120%0.196CC..  trans-73.5150.4-179.329.6-34000112.2M1 W420 Y421 K422 M791M1-P418 HydrophobicContact SD-CB 4.5Å; M1-P418 HydrophobicContact SD-CG 4.43Å; P418-W420 VanDerWaalsContact C-N 3.29Å; P418-W420 HydrophobicContact CB-CG 4.48Å; P418-W420 HydrophobicContact CG-CD2 4.49Å; P418-W420 HydrophobicContact CG-CG 4.5Å; P418-W420 HydrophobicContact CG-CZ2 4.11Å; P418-W420 VanDerWaalsContact CG-NE1 3.3Å; P418-W420 PolarHBondContact O-N 3.27Å; P418-Y421 WeakPolarHBondContact O-CB 3.33Å; P418-Y421 PolarHBondContact O-N 2.95Å; P418-K422 PolarHBondContact O-N 3.4Å; P418-M791 HydrophobicContact CG-SD 4.47Å
419P94.8Very high96.9Very high64 Ų6435 Ų3542%0.41620%0.197SC..Hα-helixtrans-53.4-39.1179.3-32.738.4000115.2E29 Y421 K422 S423E29-P419 WeakPolarHBondContact OE2-CA 3.35Å; E29-P419 WeakPolarHBondContact OE2-CB 3.27Å; P419-Y421 VanDerWaalsContact C-N 3.27Å; P419-Y421 PolarHBondContact O-N 3.1Å; P419-K422 PolarHBondContact O-N 2.79Å; P419-S423 PolarHBondContact O-N 3.47Å
420W95.3Very high97Very high14 Ų1429.7 Ų29.75%0.05318%0.177CC..Hα-helixtrans-61.5-38.1179.975-106.4000111.4P418 S423 A424 M791 A794 E795 Y798 M835P418-W420 VanDerWaalsContact C-N 3.29Å; P418-W420 HydrophobicContact CB-CG 4.48Å; P418-W420 HydrophobicContact CG-CD2 4.49Å; P418-W420 HydrophobicContact CG-CG 4.5Å; P418-W420 HydrophobicContact CG-CZ2 4.11Å; P418-W420 VanDerWaalsContact CG-NE1 3.3Å; P418-W420 PolarHBondContact O-N 3.27Å; W420-S423 WeakPolarHBondContact O-CB 3.44Å; W420-S423 PolarHBondContact O-N 2.95Å; W420-A424 WeakPolarHBondContact O-CB 3.4Å; W420-A424 PolarHBondContact O-N 2.92Å; W420-M791 HydrophobicContact CH2-SD 4.27Å; W420-M791 HydrophobicContact CZ2-CB 4.47Å; W420-M791 WeakPolarHBondContact CZ2-O 3.34Å; W420-M791 HydrophobicContact CZ2-SD 3.9Å; W420-A794 HydrophobicContact CH2-CB 3.6Å; W420-A794 HydrophobicContact CZ3-CB 4.09Å; W420-E795 HydrophobicContact CD2-CB 4.05Å; W420-E795 HydrophobicContact CD2-CG 4.02Å; W420-E795 HydrophobicContact CG-CG 4.09Å; W420-E795 HydrophobicContact CH2-CB 4.25Å; W420-E795 HydrophobicContact CZ2-CB 3.67Å; W420-E795 HydrophobicContact CZ2-CG 4.42Å; W420-Y798 HydrophobicContact CB-CD1 3.7Å; W420-Y798 HydrophobicContact CB-CE1 3.67Å; W420-Y798 HydrophobicContact CE3-CD1 4.1Å; W420-Y798 AromaticContact CE3-CG 3.99Å; W420-Y798 HydrophobicContact CE3-CG 3.99Å; W420-Y798 HydrophobicContact CG-CD1 4.43Å; W420-M835 HydrophobicContact CH2-CE 4.42Å
421Y98.2Very high97.1Very high0 Ų025.4 Ų25.40%015%0.149CC..Hα-helixtrans-70.3-45-178.5172.9-109.4000110.6L417 P418 P419 S423 A424 L425 V832 M835 Q836 L839L417-Y421 HydrophobicContact CB-CD1 4.28Å; L417-Y421 HydrophobicContact CD1-CD1 4.25Å; L417-Y421 HydrophobicContact CD1-CE1 4.1Å; L417-Y421 HydrophobicContact CD2-CD1 4.15Å; L417-Y421 HydrophobicContact CD2-CE1 4.18Å; L417-Y421 HydrophobicContact CG-CD1 4.47Å; P418-Y421 WeakPolarHBondContact O-CB 3.33Å; P418-Y421 PolarHBondContact O-N 2.95Å; P419-Y421 VanDerWaalsContact C-N 3.27Å; P419-Y421 PolarHBondContact O-N 3.1Å; Y421-S423 VanDerWaalsContact C-N 3.26Å; Y421-S423 PolarHBondContact O-N 3.38Å; Y421-A424 PolarHBondContact O-N 3.17Å; Y421-L425 HydrophobicContact CE1-CD2 4.24Å; Y421-L425 WeakPolarHBondContact O-CB 3.37Å; Y421-L425 PolarHBondContact O-N 2.99Å; Y421-V832 HydrophobicContact CE2-CG2 4.05Å; Y421-M835 HydrophobicContact CD2-CE 4.01Å; Y421-M835 HydrophobicContact CE2-CB 4.05Å; Y421-M835 HydrophobicContact CE2-CE 3.81Å; Y421-M835 HydrophobicContact CE2-SD 4.12Å; Y421-Q836 VanDerWaalsContact OH-CA 3.31Å; Y421-Q836 WeakPolarHBondContact OH-CA 3.33Å; Y421-Q836 WeakPolarHBondContact OH-CB 3.42Å; Y421-Q836 PolarHBondContact OH-N 3.01Å; Y421-Q836 VanDerWaalsContact OH-N 3.16Å; Y421-Q836 PolarHBondContact OH-OE1 3.48Å; Y421-L839 HydrophobicContact CE1-CD1 3.85Å
422K97.9Very high97.1Very high7 Ų724.6 Ų24.63%0.0315%0.145CC..Hα-helixtrans-56.7-44174.6-63173.2-178.2-179.60110.8E29 I411 L412 D414 L417 P418 P419 F426E29-K422 HydrophobicContact CB-CD 4.47Å; E29-K422 HydrophobicContact CG-CD 3.93Å; I411-K422 HydrophobicContact CG2-CG 4.41Å; I411-K422 VanDerWaalsContact O-CE 3.25Å; I411-K422 WeakPolarHBondContact O-CE 3.45Å; L412-K422 HydrophobicContact CD2-CB 4.2Å; L412-K422 HydrophobicContact CD2-CD 4.35Å; L412-K422 PolarHBondContact O-NZ 3.11Å; D414-K422 VanDerWaalsContact O-CE 3.27Å; D414-K422 WeakPolarHBondContact O-CE 3.45Å; D414-K422 PolarHBondContact O-NZ 3.25Å; L417-K422 HydrophobicContact CB-CG 4.44Å; L417-K422 VanDerWaalsContact O-CE 3.24Å; L417-K422 WeakPolarHBondContact O-CE 3.44Å; L417-K422 PolarHBondContact O-NZ 3.28Å; P418-K422 PolarHBondContact O-N 3.4Å; P419-K422 PolarHBondContact O-N 2.79Å; K422-F426 WeakPolarHBondContact O-CD2 3.31Å; K422-F426 PolarHBondContact O-N 3.48Å
423S97.4Very high97.1Very high1 Ų122.9 Ų22.91%0.00714%0.136CC..Hα-helixtrans-60.6-51174.9-178.10000112.1W31 P419 W420 Y421 N427 Y798W31-S423 PolarHBondContact N-OG 3.43Å; P419-S423 PolarHBondContact O-N 3.47Å; W420-S423 WeakPolarHBondContact O-CB 3.44Å; W420-S423 PolarHBondContact O-N 2.95Å; Y421-S423 VanDerWaalsContact C-N 3.26Å; Y421-S423 PolarHBondContact O-N 3.38Å; S423-N427 WeakPolarHBondContact O-CB 3.48Å; S423-N427 PolarHBondContact O-N 3.01Å; S423-N427 PolarHBondContact O-ND2 2.93Å; S423-N427 PolarHBondContact OG-ND2 3.41Å; S423-Y798 WeakPolarHBondContact CB-OH 3.27Å; S423-Y798 PolarHBondContact OG-OH 3.19Å
424A98.2Very high97.2Very high0 Ų016.4 Ų16.40%011%0.106CC..Hα-helixtrans-59.5-50.9179.800000112W420 Y421 F426 N427 E428 Y798 V832W420-A424 WeakPolarHBondContact O-CB 3.4Å; W420-A424 PolarHBondContact O-N 2.92Å; Y421-A424 PolarHBondContact O-N 3.17Å; A424-F426 VanDerWaalsContact C-N 3.35Å; A424-F426 PolarHBondContact O-N 3.44Å; A424-N427 PolarHBondContact O-N 3.38Å; A424-E428 WeakPolarHBondContact O-CB 3.45Å; A424-E428 VanDerWaalsContact O-CG 3.25Å; A424-E428 WeakPolarHBondContact O-CG 3.37Å; A424-E428 PolarHBondContact O-N 3.46Å; A424-Y798 HydrophobicContact CB-CD2 3.52Å; A424-Y798 HydrophobicContact CB-CE2 3.98Å; A424-Y798 HydrophobicContact CB-CG 4.24Å; A424-V832 HydrophobicContact CB-CG2 4.37Å
425L98.8Very high97.3Very high0 Ų014.6 Ų14.60%010%0.096CC..Hα-helixtrans-56.4-47.1-174.5-176.770.2000112.3I411 Y421 V832 W833 Q836I411-L425 HydrophobicContact CD1-CD2 3.86Å; I411-L425 HydrophobicContact CG2-CD2 3.97Å; Y421-L425 HydrophobicContact CE1-CD2 4.24Å; Y421-L425 WeakPolarHBondContact O-CB 3.37Å; Y421-L425 PolarHBondContact O-N 2.99Å; L425-V832 HydrophobicContact CB-CG2 4.38Å; L425-V832 HydrophobicContact CD1-CG1 4.24Å; L425-V832 HydrophobicContact CD1-CG2 4.15Å; L425-W833 HydrophobicContact CD1-CD2 3.78Å; L425-W833 HydrophobicContact CD1-CE3 4.35Å; L425-W833 HydrophobicContact CD1-CG 3.96Å; L425-W833 HydrophobicContact CD1-CH2 4.49Å; L425-W833 HydrophobicContact CD1-CZ2 3.98Å; L425-W833 HydrophobicContact CD2-CH2 4.36Å; L425-W833 HydrophobicContact CD2-CZ2 4.27Å; L425-W833 HydrophobicContact CG-CH2 4.34Å; L425-W833 HydrophobicContact CG-CZ2 3.79Å; L425-W833 PolarHBondContact O-NE1 2.85Å; L425-Q836 HydrophobicContact CD1-CB 3.99Å; L425-Q836 HydrophobicContact CD2-CB 4.36Å; L425-Q836 HydrophobicContact CD2-CG 4.29Å
426F98.8Very high97.5Very high0 Ų08.9 Ų8.90%06%0.056CC..Hα-helixtrans-80.1-43.1-179.3-66.8-58.4000112.3L176 W407 Q408 I411 L412 K422 A424 E428 L429L176-F426 HydrophobicContact CD1-CB 3.9Å; L176-F426 HydrophobicContact CD1-CD2 3.72Å; L176-F426 HydrophobicContact CD1-CG 4.15Å; L176-F426 HydrophobicContact CG-CB 4.49Å; L176-F426 HydrophobicContact CG-CD2 4.48Å; W407-F426 AromaticContact CE3-CE1 3.97Å; W407-F426 HydrophobicContact CE3-CE1 3.97Å; W407-F426 AromaticContact CH2-CD1 3.37Å; W407-F426 HydrophobicContact CH2-CD1 3.37Å; W407-F426 AromaticContact CH2-CE1 3.45Å; W407-F426 HydrophobicContact CH2-CE1 3.45Å; W407-F426 VanDerWaalsContact CH2-CE1 3.45Å; W407-F426 HydrophobicContact CZ2-CD1 4.1Å; W407-F426 HydrophobicContact CZ2-CE1 4.22Å; W407-F426 AromaticContact CZ3-CD1 3.75Å; W407-F426 HydrophobicContact CZ3-CD1 3.75Å; W407-F426 AromaticContact CZ3-CE1 3.32Å; W407-F426 HydrophobicContact CZ3-CE1 3.32Å; Q408-F426 HydrophobicContact CB-CE1 4.14Å; Q408-F426 HydrophobicContact CB-CE2 4.41Å; Q408-F426 HydrophobicContact CB-CZ 3.86Å; Q408-F426 HydrophobicContact CG-CD1 4.04Å; Q408-F426 HydrophobicContact CG-CE1 3.65Å; Q408-F426 HydrophobicContact CG-CE2 4.49Å; Q408-F426 HydrophobicContact CG-CZ 3.89Å; I411-F426 HydrophobicContact CB-CE2 4.33Å; I411-F426 HydrophobicContact CB-CZ 3.94Å; I411-F426 HydrophobicContact CD1-CE1 4.33Å; I411-F426 HydrophobicContact CD1-CZ 3.94Å; I411-F426 HydrophobicContact CG2-CE2 3.98Å; I411-F426 HydrophobicContact CG2-CZ 4Å; L412-F426 HydrophobicContact CD2-CD2 4.07Å; L412-F426 HydrophobicContact CD2-CE2 3.56Å; L412-F426 HydrophobicContact CG-CE2 3.88Å; L412-F426 HydrophobicContact CG-CZ 4.46Å; K422-F426 WeakPolarHBondContact O-CD2 3.31Å; K422-F426 PolarHBondContact O-N 3.48Å; A424-F426 VanDerWaalsContact C-N 3.35Å; A424-F426 PolarHBondContact O-N 3.44Å; F426-E428 PolarHBondContact O-N 2.85Å; F426-L429 WeakPolarHBondContact O-CB 3.37Å; F426-L429 PolarHBondContact O-N 3.14Å
427N98.8Very high97.7Very high0 Ų05.5 Ų5.50%03%0.033CC..Hα-helixtrans-73.5-28.2-173.7-70.6-49.5000113.6A175 L176 Y177 S423 A424 L429 Y430 W802 F809A175-N427 PolarHBondContact O-ND2 3.11Å; A175-N427 PolarHBondContact O-OD1 3.29Å; L176-N427 WeakPolarHBondContact CA-OD1 3.45Å; L176-N427 PolarHBondContact N-OD1 3.27Å; Y177-N427 PolarHBondContact N-OD1 2.91Å; S423-N427 WeakPolarHBondContact O-CB 3.48Å; S423-N427 PolarHBondContact O-N 3.01Å; S423-N427 PolarHBondContact O-ND2 2.93Å; S423-N427 PolarHBondContact OG-ND2 3.41Å; A424-N427 PolarHBondContact O-N 3.38Å; N427-L429 PolarHBondContact O-N 3.23Å; N427-Y430 WeakPolarHBondContact O-CB 3.44Å; N427-Y430 VanDerWaalsContact O-CD1 3.25Å; N427-Y430 WeakPolarHBondContact O-CD1 3.43Å; N427-Y430 PolarHBondContact O-N 3.38Å; N427-W802 HydrophobicContact CB-CH2 3.37Å; N427-W802 HydrophobicContact CB-CZ2 4.01Å; N427-W802 HydrophobicContact CB-CZ3 3.76Å; N427-F809 HydrophobicContact CB-CE1 4.18Å; N427-F809 HydrophobicContact CB-CZ 4.23Å
428E98.8Very high97.8Very high1 Ų15.2 Ų5.21%0.0053%0.031CC..THydrogen-bonded Turntrans-65.3-21.6173.7-69.3-64.3168.500112.8A424 F426 Y430 F431 W802 T811 L830 V832A424-E428 WeakPolarHBondContact O-CB 3.45Å; A424-E428 VanDerWaalsContact O-CG 3.25Å; A424-E428 WeakPolarHBondContact O-CG 3.37Å; A424-E428 PolarHBondContact O-N 3.46Å; F426-E428 PolarHBondContact O-N 2.85Å; E428-Y430 WeakPolarHBondContact O-CD1 3.27Å; E428-Y430 PolarHBondContact O-N 3.37Å; E428-F431 PolarHBondContact O-N 2.94Å; E428-W802 HydrophobicContact CG-CZ2 4.44Å; E428-W802 PolarHBondContact OE1-NE1 3.2Å; E428-T811 VanDerWaalsContact CD-OG1 3.31Å; E428-T811 WeakPolarHBondContact OE1-CG2 3.42Å; E428-T811 PolarHBondContact OE1-OG1 3.18Å; E428-T811 WeakPolarHBondContact OE2-CB 3.49Å; E428-T811 PolarHBondContact OE2-OG1 3.43Å; E428-L830 VanDerWaalsContact O-CD2 3.26Å; E428-L830 WeakPolarHBondContact O-CD2 3.39Å; E428-V832 HydrophobicContact CB-CG1 3.96Å; E428-V832 HydrophobicContact CG-CG1 4.24Å
429L98.8Very high98Very high2 Ų24.4 Ų4.41%0.013%0.026CC..THydrogen-bonded Turntrans-62.9-12.7174.9-71.6174.9000113.9Y177 W407 F426 N427 F431 V432 A495 L499 W500 L830 W833Y177-L429 HydrophobicContact CD1-CB 3.78Å; Y177-L429 HydrophobicContact CE1-CB 4.08Å; W407-L429 HydrophobicContact CH2-CD1 3.7Å; W407-L429 HydrophobicContact CZ3-CD1 4.45Å; F426-L429 WeakPolarHBondContact O-CB 3.37Å; F426-L429 PolarHBondContact O-N 3.14Å; N427-L429 PolarHBondContact O-N 3.23Å; L429-F431 PolarHBondContact O-N 3.25Å; L429-V432 HydrophobicContact CD2-CG2 4.26Å; L429-V432 WeakPolarHBondContact O-CB 3.45Å; L429-V432 PolarHBondContact O-N 2.65Å; L429-A495 HydrophobicContact CD2-CB 3.86Å; L429-L499 HydrophobicContact CD1-CD1 3.71Å; L429-L499 HydrophobicContact CD2-CD1 3.67Å; L429-L499 HydrophobicContact CG-CD1 4.34Å; L429-W500 HydrophobicContact CD2-CZ3 4.34Å; L429-L830 HydrophobicContact CD2-CD2 4.22Å; L429-W833 HydrophobicContact CD1-CZ2 3.67Å; L429-W833 HydrophobicContact CD2-CZ2 4.48Å; L429-W833 VanDerWaalsContact CD2-NE1 3.28Å; L429-W833 HydrophobicContact CG-CZ2 4.28Å
430Y98.8Very high98.2Very high0 Ų01.4 Ų1.40%01%0.006CC..Hα-helixtrans-49.5-34.2174.688.8-82.5000112.1P98 N427 E428 V432 A433 D434 F809 Q810 T811 A825P98-Y430 HydrophobicContact CG-CD2 4.27Å; N427-Y430 WeakPolarHBondContact O-CB 3.44Å; N427-Y430 VanDerWaalsContact O-CD1 3.25Å; N427-Y430 WeakPolarHBondContact O-CD1 3.43Å; N427-Y430 PolarHBondContact O-N 3.38Å; E428-Y430 WeakPolarHBondContact O-CD1 3.27Å; E428-Y430 PolarHBondContact O-N 3.37Å; Y430-V432 VanDerWaalsContact C-N 3.26Å; Y430-V432 PolarHBondContact O-N 3.35Å; Y430-A433 PolarHBondContact O-N 3.23Å; Y430-D434 HydrophobicContact CD2-CB 4.08Å; Y430-D434 WeakPolarHBondContact O-CB 3.4Å; Y430-D434 PolarHBondContact O-N 2.96Å; Y430-F809 HydrophobicContact CD1-CD1 4.08Å; Y430-F809 HydrophobicContact CD2-CB 4.2Å; Y430-F809 HydrophobicContact CD2-CD1 4.16Å; Y430-F809 HydrophobicContact CE2-CB 4.32Å; Y430-F809 WeakPolarHBondContact CE2-O 3.5Å; Y430-F809 HydrophobicContact CG-CB 4.44Å; Y430-F809 AromaticContact CG-CD1 3.68Å; Y430-F809 HydrophobicContact CG-CD1 3.68Å; Y430-F809 PolarHBondContact OH-O 3.03Å; Y430-Q810 WeakPolarHBondContact OH-CA 3.43Å; Y430-Q810 PolarHBondContact OH-N 3.23Å; Y430-T811 PolarHBondContact OH-N 2.76Å; Y430-A825 WeakPolarHBondContact OH-CA 3.09Å
431F98.8Very high98.2Very high0 Ų02.8 Ų2.80%01%0.013CC..Hα-helixtrans-69.6-21.6-175.6-162.1-95.3000113.2E428 L429 A433 G435 Y474 L475 A825 M827 L830E428-F431 PolarHBondContact O-N 2.94Å; L429-F431 PolarHBondContact O-N 3.25Å; F431-A433 PolarHBondContact O-N 2.66Å; F431-G435 VanDerWaalsContact CZ-CA 3.5Å; F431-G435 WeakPolarHBondContact O-CA 3.42Å; F431-G435 PolarHBondContact O-N 3.36Å; F431-Y474 HydrophobicContact CD1-CD2 4.2Å; F431-Y474 AromaticContact CE1-CD2 3.95Å; F431-Y474 HydrophobicContact CE1-CD2 3.95Å; F431-Y474 HydrophobicContact CE1-CE2 4.46Å; F431-L475 VanDerWaalsContact CE1-O 3.26Å; F431-L475 WeakPolarHBondContact CE1-O 3.34Å; F431-L475 WeakPolarHBondContact CZ-O 3.18Å; F431-A825 HydrophobicContact CE2-CB 4.23Å; F431-A825 WeakPolarHBondContact CE2-O 3.48Å; F431-M827 HydrophobicContact CD1-CB 3.85Å; F431-M827 HydrophobicContact CE1-CB 3.35Å; F431-M827 HydrophobicContact CZ-CB 4.18Å; F431-L830 HydrophobicContact CB-CD1 4.42Å; F431-L830 HydrophobicContact CB-CD2 4.41Å; F431-L830 HydrophobicContact CB-CG 4.44Å; F431-L830 HydrophobicContact CD1-CD1 4.12Å
432V98.6Very high98Very high2 Ų23.8 Ų3.81%0.0122%0.019CC..Hα-helixtrans-63.7-33174.5178.70000111I102 L429 Y430 T437 L496 W500 L830I102-V432 HydrophobicContact CD1-CG1 3.76Å; I102-V432 HydrophobicContact CG1-CG1 4.09Å; I102-V432 HydrophobicContact CG2-CG1 4.39Å; L429-V432 HydrophobicContact CD2-CG2 4.26Å; L429-V432 WeakPolarHBondContact O-CB 3.45Å; L429-V432 PolarHBondContact O-N 2.65Å; Y430-V432 VanDerWaalsContact C-N 3.26Å; Y430-V432 PolarHBondContact O-N 3.35Å; V432-T437 WeakPolarHBondContact O-CB 3.4Å; V432-T437 WeakPolarHBondContact O-CG2 3.25Å; V432-T437 PolarHBondContact O-OG1 2.98Å; V432-L496 HydrophobicContact CG1-CD2 3.94Å; V432-L496 HydrophobicContact CG2-CD2 4.38Å; V432-W500 HydrophobicContact CB-CZ3 4.34Å; V432-W500 HydrophobicContact CG1-CE3 4.17Å; V432-W500 HydrophobicContact CG1-CH2 4.48Å; V432-W500 HydrophobicContact CG1-CZ3 3.93Å; V432-W500 HydrophobicContact CG2-CZ3 4.12Å; V432-L830 HydrophobicContact CG2-CD1 4.12Å; V432-L830 HydrophobicContact CG2-CD2 4Å
433A98.3Very high97.5Very high0 Ų06.3 Ų6.30%04%0.037CC..Hα-helixtrans-94.3-46.1175.600000112.6T106 Y177 Y430 F431 G435 T437T106-A433 HydrophobicContact CG2-CB 3.88Å; T106-A433 WeakPolarHBondContact CG2-O 3.24Å; Y177-A433 VanDerWaalsContact OH-CB 3.28Å; Y177-A433 WeakPolarHBondContact OH-CB 3.19Å; Y430-A433 PolarHBondContact O-N 3.23Å; F431-A433 PolarHBondContact O-N 2.66Å; A433-G435 VanDerWaalsContact C-N 3.34Å; A433-T437 PolarHBondContact O-OG1 2.86Å
434D98.1Very high96.9Very high0 Ų015.2 Ų15.20%08%0.079CC..Hα-helixtrans-9718.9-172.4-165.420.3000112.9P98 T106 T108 R117 Y125 Y430 G436 Q478P98-D434 HydrophobicContact CB-CB 3.73Å; P98-D434 HydrophobicContact CG-CB 3.66Å; T106-D434 HydrophobicContact CG2-CB 4.35Å; T106-D434 PolarHBondContact OG1-OD1 2.92Å; T108-D434 PolarHBondContact OG1-OD2 2.78Å; R117-D434 IonicContact CZ-OD2 3.57Å; R117-D434 IonicContact NE-OD1 2.78Å; R117-D434 IonicContact NE-OD2 3.97Å; R117-D434 PolarHBondContact NE-OD2 2.6Å; R117-D434 IonicContact NH2-OD2 3.82Å; R117-D434 PolarHBondContact NH2-OD2 3.15Å; Y125-D434 PolarHBondContact OH-O 2.96Å; Y430-D434 HydrophobicContact CD2-CB 4.08Å; Y430-D434 WeakPolarHBondContact O-CB 3.4Å; Y430-D434 PolarHBondContact O-N 2.96Å; D434-G436 VanDerWaalsContact C-N 3.26Å; D434-G436 PolarHBondContact O-N 2.82Å; D434-Q478 PolarHBondContact O-NE2 3.02Å
435G97.8Very high96.3Very high0 Ų021.9 Ų21.90%011%0.114CC..THydrogen-bonded Turntrans-89.726.1174.500000112.9Y125 F431 A433 T437 L475Y125-G435 VanDerWaalsContact OH-C 3.24Å; F431-G435 VanDerWaalsContact CZ-CA 3.5Å; F431-G435 WeakPolarHBondContact O-CA 3.42Å; F431-G435 PolarHBondContact O-N 3.36Å; A433-G435 VanDerWaalsContact C-N 3.34Å; G435-T437 PolarHBondContact O-N 3.38Å; G435-L475 VanDerWaalsContact O-CB 3.29Å; G435-L475 WeakPolarHBondContact O-CB 3.39Å; G435-L475 PolarHBondContact O-N 3.13Å
436G97.3Very high95.9Very high0 Ų022.7 Ų22.70%012%0.121CC..THydrogen-bonded Turntrans73.919.5-177.300000111.8G123 Y125 D434 Y483G123-G436 PolarHBondContact N-O 3.13Å; Y125-G436 WeakPolarHBondContact OH-CA 3.34Å; Y125-G436 PolarHBondContact OH-N 2.8Å; D434-G436 VanDerWaalsContact C-N 3.26Å; D434-G436 PolarHBondContact O-N 2.82Å; G436-Y483 WeakPolarHBondContact O-CE1 3.43Å; G436-Y483 PolarHBondContact O-OH 3.4Å
437T98.4Very high95.6Very high0 Ų026.1 Ų26.10%014%0.139CC..  trans-60.3137-165.6-53.70000112.1I102 V432 A433 G435 F472 A473I102-T437 HydrophobicContact CG2-CG2 3.88Å; V432-T437 WeakPolarHBondContact O-CB 3.4Å; V432-T437 WeakPolarHBondContact O-CG2 3.25Å; V432-T437 PolarHBondContact O-OG1 2.98Å; A433-T437 PolarHBondContact O-OG1 2.86Å; G435-T437 PolarHBondContact O-N 3.38Å; T437-F472 HydrophobicContact CG2-CD2 4.27Å; T437-F472 HydrophobicContact CG2-CE2 3.3Å; T437-F472 HydrophobicContact CG2-CZ 3.55Å; T437-A473 CarbonylContact C-O 3.47Å; T437-A473 WeakPolarHBondContact CA-O 3.27Å
438V98.1Very high95.3Very high1 Ų126.4 Ų26.41%0.00614%0.141CC..EExtended strand (participates in β ladder)trans-122.3135.4168.7-65.60000108.9P122 F364 A473 Y483 W552P122-V438 HydrophobicContact CB-CG1 3.69Å; P122-V438 HydrophobicContact CG-CG1 4.43Å; F364-V438 HydrophobicContact CE1-CG1 4.06Å; F364-V438 HydrophobicContact CE1-CG2 4.5Å; F364-V438 HydrophobicContact CZ-CG1 4.25Å; F364-V438 HydrophobicContact CZ-CG2 4.21Å; V438-A473 HydrophobicContact CG2-CB 3.67Å; V438-A473 PolarHBondContact N-O 3Å; V438-A473 PolarHBondContact O-N 3.39Å; V438-Y483 WeakPolarHBondContact CG1-OH 3.5Å; V438-Y483 HydrophobicContact CG2-CE1 3.95Å; V438-W552 HydrophobicContact CG2-CH2 3.98Å; V438-W552 HydrophobicContact CG2-CZ2 4.45Å
439W98.6Very high95Very high1 Ų126.4 Ų26.40%0.00414%0.141CC..EExtended strand (participates in β ladder)trans-134.1110.3174.6-174.42.5000107.2I102 Y206 R373 R374 Y469 R471 F472 L503I102-W439 HydrophobicContact CB-CE3 4.18Å; I102-W439 HydrophobicContact CB-CZ3 4.43Å; I102-W439 HydrophobicContact CG2-CE3 4.01Å; Y206-W439 AromaticContact CD1-CH2 3.97Å; Y206-W439 HydrophobicContact CD1-CH2 3.97Å; Y206-W439 HydrophobicContact CD1-CZ2 4.28Å; Y206-W439 HydrophobicContact CG-CH2 4.45Å; Y206-W439 VanDerWaalsContact O-CH2 3.23Å; Y206-W439 WeakPolarHBondContact O-CH2 3.46Å; R373-W439 CarbonylContact C-O 3.54Å; R373-W439 WeakPolarHBondContact CA-O 3.41Å; R374-W439 HydrophobicContact CB-CB 4.15Å; R374-W439 HydrophobicContact CB-CD2 3.62Å; R374-W439 HydrophobicContact CB-CE3 4.16Å; R374-W439 HydrophobicContact CB-CG 3.61Å; R374-W439 HydrophobicContact CG-CD2 3.66Å; R374-W439 VanDerWaalsContact CG-CE2 3.44Å; R374-W439 HydrophobicContact CG-CE3 4.07Å; R374-W439 HydrophobicContact CG-CG 4.14Å; R374-W439 HydrophobicContact CG-CH2 4.09Å; R374-W439 HydrophobicContact CG-CZ2 3.67Å; R374-W439 HydrophobicContact CG-CZ3 4.27Å; R374-W439 PolarHBondContact N-O 3.3Å; W439-Y469 PolarHBondContact NE1-O 2.96Å; W439-R471 WeakPolarHBondContact CA-O 3.24Å; W439-F472 HydrophobicContact CB-CD2 4.17Å; W439-F472 HydrophobicContact CG-CD2 4.23Å; W439-L503 HydrophobicContact CD2-CD2 4.14Å; W439-L503 HydrophobicContact CE3-CD1 4.42Å; W439-L503 HydrophobicContact CH2-CD1 4.35Å; W439-L503 HydrophobicContact CH2-CD2 4.16Å; W439-L503 HydrophobicContact CZ2-CD2 3.57Å; W439-L503 HydrophobicContact CZ3-CD1 4.29Å
440T97.7Very high94.4Very high0 Ų027.2 Ų27.20%015%0.15CC..EExtended strand (participates in β ladder)trans-120.1149.9-169.659.50000112.2I362 H371 Y372 G470 R471 W552I362-T440 HydrophobicContact CD1-CG2 4.18Å; H371-T440 HydrophobicContact CB-CG2 3.91Å; Y372-T440 CarbonylContact O-C 3.54Å; Y372-T440 WeakPolarHBondContact O-CA 3.29Å; Y372-T440 WeakPolarHBondContact O-CB 3.18Å; T440-G470 CarbonylContact O-C 3.52Å; T440-G470 WeakPolarHBondContact O-CA 3.43Å; T440-R471 PolarHBondContact N-O 3.29Å; T440-R471 PolarHBondContact O-N 3.46Å; T440-W552 HydrophobicContact CG2-CH2 4.31Å
441E96.1Very high93.9Very high43 Ų4330.3 Ų30.320%0.20118%0.181CC..PPolyproline II helixtrans-64.4145.3167.8-69.4-65.6109.600110.5Y372 R374 R377Y372-E441 PolarHBondContact O-N 3.05Å; R374-E441 WeakPolarHBondContact CD-OE1 3.43Å; R374-E441 IonicContact CZ-OE1 3.32Å; R374-E441 IonicContact NE-OE1 3.3Å; R374-E441 IonicContact NH1-OE1 3.34Å; R374-E441 PolarHBondContact NH1-OE1 2.74Å; R377-E441 IonicContact CZ-OE1 3.33Å; R377-E441 IonicContact CZ-OE2 3.12Å; R377-E441 VanDerWaalsContact NE-CD 3.31Å; R377-E441 IonicContact NE-OE1 2.7Å; R377-E441 PolarHBondContact NE-OE1 3.21Å; R377-E441 IonicContact NE-OE2 3.09Å; R377-E441 PolarHBondContact NE-OE2 2.82Å; R377-E441 IonicContact NH2-OE1 2.99Å; R377-E441 PolarHBondContact NH2-OE1 3.31Å; R377-E441 IonicContact NH2-OE2 2.83Å; R377-E441 PolarHBondContact NH2-OE2 3.38Å
442L93.8Very high93.4Very high22 Ų2231.7 Ų31.712%0.11519%0.19CC..PPolyproline II helixtrans-83.8123.5171.7-171.570.3000108.5A446 I448 Q462 V466 K467 R471L442-A446 HydrophobicContact CD1-CB 3.46Å; L442-A446 VanDerWaalsContact CD1-CB 3.46Å; L442-A446 HydrophobicContact CG-CB 3.77Å; L442-I448 HydrophobicContact CD1-CG2 3.97Å; L442-Q462 HydrophobicContact CD2-CB 4Å; L442-Q462 HydrophobicContact CD2-CG 3.93Å; L442-V466 HydrophobicContact CD1-CG1 4.34Å; L442-V466 HydrophobicContact CD2-CG1 4.16Å; L442-K467 HydrophobicContact CD2-CB 4.31Å; L442-R471 HydrophobicContact CD1-CG 3.88Å
443S87.3Confident93.1Very high60 Ų6035.5 Ų35.542%0.4220%0.204SC..PPolyproline II helixtrans-65.9151.4177.171.70000111.4D445 A446S443-D445 WeakPolarHBondContact CB-OD1 3.17Å; S443-D445 PolarHBondContact O-N 3.14Å; S443-D445 PolarHBondContact OG-OD1 2.85Å; S443-A446 VanDerWaalsContact O-CB 3.25Å; S443-A446 WeakPolarHBondContact O-CB 3.43Å; S443-A446 PolarHBondContact O-N 3.32Å; S443-A446 PolarHBondContact OG-N 3.12Å
444E84.4Confident92.5Very high188 Ų18838.1 Ų38.188%0.87922%0.222SC*.THydrogen-bonded Turntrans-62.9-23.6-177.1-66.1-168.9158.600113.7Q462E444-Q462 PolarHBondContact O-NE2 3.16Å
445D86.6Confident92Very high139 Ų13945.3 Ų45.374%0.74326%0.256SS*.THydrogen-bonded Turntrans-98.41.8178.566.6-35.4000113.3S443S443-D445 WeakPolarHBondContact CB-OD1 3.17Å; S443-D445 PolarHBondContact O-N 3.14Å; S443-D445 PolarHBondContact OG-OD1 2.85Å
446A89.8Confident91.5Very high18 Ų1851.2 Ų51.215%0.14929%0.287CS..  trans-64.3144.9-177.800000112.1L442 S443 Q462L442-A446 HydrophobicContact CD1-CB 3.46Å; L442-A446 VanDerWaalsContact CD1-CB 3.46Å; L442-A446 HydrophobicContact CG-CB 3.77Å; S443-A446 VanDerWaalsContact O-CB 3.25Å; S443-A446 WeakPolarHBondContact O-CB 3.43Å; S443-A446 PolarHBondContact O-N 3.32Å; S443-A446 PolarHBondContact OG-N 3.12Å; A446-Q462 WeakPolarHBondContact O-CG 3.48Å; A446-Q462 PolarHBondContact O-NE2 3.47Å
447D92.4Very high90.8Very high71 Ų7152.7 Ų52.738%0.3830%0.303SS..  trans-131110170.4-172.7-12.8000109.1S449 R453 A461D447-S449 VanDerWaalsContact OD1-CB 3.29Å; D447-S449 WeakPolarHBondContact OD1-CB 3.33Å; D447-S449 PolarHBondContact OD1-N 3.08Å; D447-S449 PolarHBondContact OD1-OG 3.33Å; D447-R453 IonicContact OD1-CZ 3.53Å; D447-R453 IonicContact OD1-NH1 2.9Å; D447-R453 PolarHBondContact OD1-NH1 3.43Å; D447-R453 IonicContact OD2-CZ 2.74Å; D447-R453 IonicContact OD2-NH1 3.47Å; D447-R453 PolarHBondContact OD2-NH1 3.47Å; D447-R453 IonicContact OD2-NH2 2.84Å; D447-R453 PolarHBondContact OD2-NH2 2.86Å; D447-A461 WeakPolarHBondContact CA-O 3.11Å
448I93.8Very high90.4Very high7 Ų752.8 Ų52.84%0.03630%0.304CS..  trans-99.42.1177.874.2169.8000112.5L442 G450 A461 P463 V466 G513L442-I448 HydrophobicContact CD1-CG2 3.97Å; I448-G450 PolarHBondContact O-N 3.49Å; I448-A461 PolarHBondContact N-O 3.47Å; I448-P463 HydrophobicContact CD1-CG 3.9Å; I448-P463 HydrophobicContact CG1-CG 4.19Å; I448-V466 HydrophobicContact CD1-CB 3.98Å; I448-V466 HydrophobicContact CD1-CG1 3.96Å; I448-V466 HydrophobicContact CD1-CG2 3.7Å; I448-G513 WeakPolarHBondContact O-CA 3.47Å
449S91.2Very high90.2Very high0 Ų052.7 Ų52.70%030%0.303CS..SBendtrans-71.9-12.2-176.468.90000114.4D447 G451 V452 R453 L459 V516D447-S449 VanDerWaalsContact OD1-CB 3.29Å; D447-S449 WeakPolarHBondContact OD1-CB 3.33Å; D447-S449 PolarHBondContact OD1-N 3.08Å; D447-S449 PolarHBondContact OD1-OG 3.33Å; S449-G451 VanDerWaalsContact C-N 3.25Å; S449-G451 PolarHBondContact O-N 2.83Å; S449-G451 PolarHBondContact OG-N 2.89Å; S449-V452 WeakPolarHBondContact CB-O 3.42Å; S449-R453 PolarHBondContact OG-NH1 2.88Å; S449-L459 WeakPolarHBondContact CB-O 3.31Å; S449-V516 VanDerWaalsContact O-CG2 3.27Å; S449-V516 WeakPolarHBondContact O-CG2 3.2Å
450G86.8Confident89.9Confident20 Ų2054.5 Ų54.521%0.20632%0.315CS..THydrogen-bonded Turntrans71.617.8-173.300000115.2I448 G513 Q517I448-G450 PolarHBondContact O-N 3.49Å; G450-G513 VanDerWaalsContact CA-O 3.26Å; G450-G513 WeakPolarHBondContact CA-O 3.42Å; G450-Q517 WeakPolarHBondContact O-CG 3.45Å
451G87.8Confident89.6Confident64 Ų6456 Ų5666%0.6633%0.327SS*.THydrogen-bonded Turntrans86.73.4176.300000114.6S449S449-G451 VanDerWaalsContact C-N 3.25Å; S449-G451 PolarHBondContact O-N 2.83Å; S449-G451 PolarHBondContact OG-N 2.89Å
452V89.4Confident89.4Confident29 Ų2956.2 Ų56.218%0.17633%0.328CS..  trans-114.1121171.9-1720000108.5S449 D456 G458 L459 V516S449-V452 WeakPolarHBondContact CB-O 3.42Å; V452-D456 HydrophobicContact CG1-CB 3.94Å; V452-G458 WeakPolarHBondContact O-CA 3.49Å; V452-L459 PolarHBondContact O-N 3.13Å; V452-L459 VanDerWaalsContact O-N 3.1Å; V452-V516 HydrophobicContact CB-CB 4.36Å; V452-V516 HydrophobicContact CB-CG2 4.13Å; V452-V516 HydrophobicContact CG2-CB 3.91Å; V452-V516 HydrophobicContact CG2-CG2 3.99Å
453R91Very high89.4Confident83 Ų8355.3 Ų55.331%0.31332%0.324SS..  trans-86.3164.2-177.4-62.9-64.7-174.3-140.3-1.4112.1D447 S449 E455 D456 G457 G458D447-R453 IonicContact OD1-CZ 3.53Å; D447-R453 IonicContact OD1-NH1 2.9Å; D447-R453 PolarHBondContact OD1-NH1 3.43Å; D447-R453 IonicContact OD2-CZ 2.74Å; D447-R453 IonicContact OD2-NH1 3.47Å; D447-R453 PolarHBondContact OD2-NH1 3.47Å; D447-R453 IonicContact OD2-NH2 2.84Å; D447-R453 PolarHBondContact OD2-NH2 2.86Å; S449-R453 PolarHBondContact OG-NH1 2.88Å; R453-E455 HydrophobicContact CB-CG 4.1Å; R453-E455 WeakPolarHBondContact CB-OE1 3.36Å; R453-E455 VanDerWaalsContact CB-OE2 3.27Å; R453-E455 WeakPolarHBondContact CB-OE2 3.46Å; R453-E455 PolarHBondContact O-N 2.86Å; R453-D456 CarbonylContact O-C 3.48Å; R453-D456 PolarHBondContact O-N 3.38Å; R453-G457 PolarHBondContact O-N 2.63Å; R453-G458 WeakPolarHBondContact O-CA 3.48Å; R453-G458 PolarHBondContact O-N 2.68Å
454S86.8Confident89.8Confident55 Ų5556.2 Ų56.239%0.38534%0.335SS..G310 helixtrans-56-37.2-179.1-61.70000113.5D456 G457 G458 P460S454-D456 PolarHBondContact O-N 3.05Å; S454-G457 PolarHBondContact O-N 3.18Å; S454-G458 WeakPolarHBondContact CA-O 3.34Å; S454-P460 VanDerWaalsContact OG-CD 3.31Å; S454-P460 WeakPolarHBondContact OG-CD 3.44Å
455E86.4Confident90.4Very high150 Ų15048 Ų4870%0.70130%0.297SS*.G310 helixtrans-61.1-25.8175.456.4-92.2-147.400113.8R453R453-E455 HydrophobicContact CB-CG 4.1Å; R453-E455 WeakPolarHBondContact CB-OE1 3.36Å; R453-E455 VanDerWaalsContact CB-OE2 3.27Å; R453-E455 WeakPolarHBondContact CB-OE2 3.46Å; R453-E455 PolarHBondContact O-N 2.86Å
456D87.1Confident90.9Very high124 Ų12441.4 Ų41.466%0.66326%0.262SS*.G310 helixtrans-105.216.8-180-61-46.9000112.3V452 R453 S454V452-D456 HydrophobicContact CG1-CB 3.94Å; R453-D456 CarbonylContact O-C 3.48Å; R453-D456 PolarHBondContact O-N 3.38Å; S454-D456 PolarHBondContact O-N 3.05Å
457G83.4Confident91.1Very high31 Ų3146.4 Ų46.432%0.3228%0.28SS..THydrogen-bonded Turntrans79.821.4-179.100000114.7R453 S454 P595R453-G457 PolarHBondContact O-N 2.63Å; S454-G457 PolarHBondContact O-N 3.18Å; G457-P595 WeakPolarHBondContact O-CB 3.06Å; G457-P595 WeakPolarHBondContact O-CG 3.04Å
458G89.9Confident91.3Very high2 Ų247.9 Ų47.92%0.02128%0.284CS..SBendtrans-106-147.9172.900000113.3V452 R453 S454V452-G458 WeakPolarHBondContact O-CA 3.49Å; R453-G458 WeakPolarHBondContact O-CA 3.48Å; R453-G458 PolarHBondContact O-N 2.68Å; S454-G458 WeakPolarHBondContact CA-O 3.34Å
459L93.3Very high91.5Very high0 Ų049.2 Ų49.20%029%0.289CS..  trans-114.4160.9-175.8-64.3174.9000112.1S449 V452 Y509 A512 G513 D592 I596S449-L459 WeakPolarHBondContact CB-O 3.31Å; V452-L459 PolarHBondContact O-N 3.13Å; V452-L459 VanDerWaalsContact O-N 3.1Å; L459-Y509 HydrophobicContact CD1-CD1 4.38Å; L459-Y509 HydrophobicContact CD2-CD1 4.22Å; L459-Y509 HydrophobicContact CD2-CE1 4.29Å; L459-A512 HydrophobicContact CD1-CB 3.68Å; L459-G513 VanDerWaalsContact CD1-N 3.33Å; L459-D592 HydrophobicContact CD2-CB 4.03Å; L459-D592 WeakPolarHBondContact CD2-O 3.33Å; L459-I596 HydrophobicContact CD2-CG1 4.33Å
460P91.9Very high91.8Very high39 Ų3949.2 Ų49.225%0.25329%0.289SS..  trans-58147.5163.6-20.832.6000111.1S454 Q462 P463S454-P460 VanDerWaalsContact OG-CD 3.31Å; S454-P460 WeakPolarHBondContact OG-CD 3.44Å; P460-Q462 VanDerWaalsContact C-N 3.27Å; P460-Q462 PolarHBondContact O-N 3.48Å; P460-P463 HydrophobicContact CB-CG 4.31Å; P460-P463 WeakPolarHBondContact O-CD 3.25Å
461A91.5Very high92.3Very high30 Ų3050.2 Ų50.225%0.24829%0.287CS..SBendtrans-56-44.3177.100000112.5D447 I448D447-A461 WeakPolarHBondContact CA-O 3.11Å; I448-A461 PolarHBondContact N-O 3.47Å
462Q92.6Very high92.8Very high48 Ų4847.1 Ų47.122%0.22426%0.255CS..SBendtrans-135.286.4179.2-62.8177.116.900107.5L442 E444 A446 P460 A464L442-Q462 HydrophobicContact CD2-CB 4Å; L442-Q462 HydrophobicContact CD2-CG 3.93Å; E444-Q462 PolarHBondContact O-NE2 3.16Å; A446-Q462 WeakPolarHBondContact O-CG 3.48Å; A446-Q462 PolarHBondContact O-NE2 3.47Å; P460-Q462 VanDerWaalsContact C-N 3.27Å; P460-Q462 PolarHBondContact O-N 3.48Å; Q462-A464 PolarHBondContact O-N 2.88Å
463P94.6Very high93.3Very high3 Ų345.8 Ų45.82%0.01925%0.247CC..  trans-53.1136.2174.5-25.135.9000109.9I448 P460 L465 V466 K467 Y509I448-P463 HydrophobicContact CD1-CG 3.9Å; I448-P463 HydrophobicContact CG1-CG 4.19Å; P460-P463 HydrophobicContact CB-CG 4.31Å; P460-P463 WeakPolarHBondContact O-CD 3.25Å; P463-L465 PolarHBondContact O-N 3.46Å; P463-L465 VanDerWaalsContact O-N 3.11Å; P463-V466 HydrophobicContact CB-CG2 4.27Å; P463-V466 HydrophobicContact CG-CG2 4.49Å; P463-V466 PolarHBondContact O-N 3.44Å; P463-K467 PolarHBondContact O-N 2.83Å; P463-Y509 HydrophobicContact CB-CD1 3.85Å; P463-Y509 HydrophobicContact CB-CD2 4.36Å; P463-Y509 HydrophobicContact CB-CE1 3.83Å; P463-Y509 HydrophobicContact CB-CE2 4.34Å; P463-Y509 HydrophobicContact CB-CG 4.13Å; P463-Y509 HydrophobicContact CG-CD1 3.59Å; P463-Y509 HydrophobicContact CG-CE1 3.94Å; P463-Y509 HydrophobicContact CG-CG 4.06Å
464A94.8Very high93.6Very high79 Ų7941.8 Ų41.865%0.65323%0.232SC*.Hα-helixtrans-53.9-38.7-173.400000112.1Q462 K467 E468Q462-A464 PolarHBondContact O-N 2.88Å; A464-K467 PolarHBondContact O-N 2.53Å; A464-E468 WeakPolarHBondContact O-CB 3.2Å; A464-E468 PolarHBondContact O-N 3.42Å
465L96.8Very high94.2Very high17 Ų1739.2 Ų39.29%0.08921%0.214CC..Hα-helixtrans-60.6-47.1175.8-176.5146.3000112.3P463 K467 E468 Y469 K502 L505 Y509P463-L465 PolarHBondContact O-N 3.46Å; P463-L465 VanDerWaalsContact O-N 3.11Å; L465-K467 VanDerWaalsContact C-N 3.34Å; L465-E468 PolarHBondContact O-N 2.75Å; L465-Y469 HydrophobicContact CG-CD2 4.19Å; L465-Y469 WeakPolarHBondContact O-CB 3.38Å; L465-Y469 VanDerWaalsContact O-CD2 3.31Å; L465-Y469 WeakPolarHBondContact O-CD2 3.34Å; L465-Y469 PolarHBondContact O-N 2.94Å; L465-K502 HydrophobicContact CD1-CD 3.92Å; L465-K502 WeakPolarHBondContact CD2-O 3.25Å; L465-L505 HydrophobicContact CD1-CB 3.67Å; L465-L505 HydrophobicContact CD1-CD1 3.58Å; L465-L505 HydrophobicContact CD1-CG 4.28Å; L465-L505 HydrophobicContact CD2-CB 3.88Å; L465-L505 HydrophobicContact CG-CB 4.47Å; L465-Y509 HydrophobicContact CB-CE2 4.34Å; L465-Y509 HydrophobicContact CD2-CD2 4.24Å; L465-Y509 HydrophobicContact CD2-CE2 4.47Å
466V96.8Very high94.8Very high0 Ų032.6 Ų32.60%018%0.183CC..Hα-helixtrans-70.7-34-179.8-173.10000111.1L442 I448 P463 G470 R471 Y509L442-V466 HydrophobicContact CD1-CG1 4.34Å; L442-V466 HydrophobicContact CD2-CG1 4.16Å; I448-V466 HydrophobicContact CD1-CB 3.98Å; I448-V466 HydrophobicContact CD1-CG1 3.96Å; I448-V466 HydrophobicContact CD1-CG2 3.7Å; P463-V466 HydrophobicContact CB-CG2 4.27Å; P463-V466 HydrophobicContact CG-CG2 4.49Å; P463-V466 PolarHBondContact O-N 3.44Å; V466-G470 WeakPolarHBondContact O-CA 3.44Å; V466-G470 PolarHBondContact O-N 2.84Å; V466-R471 HydrophobicContact CG1-CG 4Å; V466-Y509 HydrophobicContact CG2-CD2 4.11Å; V466-Y509 HydrophobicContact CG2-CG 4.12Å
467K95.7Very high95.2Very high123 Ų12326.7 Ų26.754%0.53515%0.152SC..Hα-helixtrans-63.6-41.9173.2-173.2173.1-176.4166.30112R377 L442 P463 A464 L465R377-K467 PolarHBondContact NH2-O 2.77Å; R377-K467 VanDerWaalsContact NH2-O 3.1Å; L442-K467 HydrophobicContact CD2-CB 4.31Å; P463-K467 PolarHBondContact O-N 2.83Å; A464-K467 PolarHBondContact O-N 2.53Å; L465-K467 VanDerWaalsContact C-N 3.34Å
468E96.6Very high95.6Very high101 Ų10125.6 Ų25.647%0.47214%0.138SC..Hα-helixtrans-72.9-44.9179.7-172.6-179.5162.300111.7R374 R377 A464 L465R374-E468 VanDerWaalsContact CZ-O 3.31Å; R374-E468 PolarHBondContact NH1-O 3.24Å; R374-E468 PolarHBondContact NH2-O 3.47Å; R377-E468 PolarHBondContact NH1-O 3.24Å; R377-E468 PolarHBondContact NH2-O 3.14Å; A464-E468 WeakPolarHBondContact O-CB 3.2Å; A464-E468 PolarHBondContact O-N 3.42Å; L465-E468 PolarHBondContact O-N 2.75Å
469Y97.7Very high95.7Very high35 Ų3526.8 Ų26.814%0.13714%0.143CC..Hα-helixtrans-103.5-4.6-170.9-65-82.3000114.5Y206 W439 L465 K502Y206-Y469 AromaticContact CD1-CD1 3.9Å; Y206-Y469 HydrophobicContact CD1-CD1 3.9Å; Y206-Y469 HydrophobicContact CD1-CE1 4.24Å; Y206-Y469 HydrophobicContact CD2-CD1 4.05Å; Y206-Y469 AromaticContact CD2-CE1 3.54Å; Y206-Y469 HydrophobicContact CD2-CE1 3.54Å; Y206-Y469 HydrophobicContact CE1-CD1 4.36Å; Y206-Y469 HydrophobicContact CE2-CD1 4.48Å; Y206-Y469 AromaticContact CE2-CE1 3.94Å; Y206-Y469 HydrophobicContact CE2-CE1 3.94Å; Y206-Y469 AromaticContact CG-CD1 3.73Å; Y206-Y469 HydrophobicContact CG-CD1 3.73Å; Y206-Y469 AromaticContact CG-CE1 3.7Å; Y206-Y469 HydrophobicContact CG-CE1 3.7Å; W439-Y469 PolarHBondContact NE1-O 2.96Å; L465-Y469 HydrophobicContact CG-CD2 4.19Å; L465-Y469 WeakPolarHBondContact O-CB 3.38Å; L465-Y469 VanDerWaalsContact O-CD2 3.31Å; L465-Y469 WeakPolarHBondContact O-CD2 3.34Å; L465-Y469 PolarHBondContact O-N 2.94Å; Y469-K502 HydrophobicContact CD1-CB 3.66Å; Y469-K502 HydrophobicContact CD1-CG 4.1Å; Y469-K502 HydrophobicContact CD2-CB 3.72Å; Y469-K502 HydrophobicContact CD2-CD 4.25Å; Y469-K502 HydrophobicContact CD2-CG 4.03Å; Y469-K502 HydrophobicContact CE1-CB 3.92Å; Y469-K502 HydrophobicContact CE1-CG 3.81Å; Y469-K502 HydrophobicContact CE2-CB 4.01Å; Y469-K502 HydrophobicContact CE2-CD 3.86Å; Y469-K502 HydrophobicContact CE2-CG 3.77Å; Y469-K502 HydrophobicContact CG-CB 3.56Å; Y469-K502 HydrophobicContact CG-CG 4.22Å
470G97.5Very high95.7Very high0 Ų028.2 Ų28.20%015%0.149CC..  trans75.9179-179.400000113.7T440 V466 S506T440-G470 CarbonylContact O-C 3.52Å; T440-G470 WeakPolarHBondContact O-CA 3.43Å; V466-G470 WeakPolarHBondContact O-CA 3.44Å; V466-G470 PolarHBondContact O-N 2.84Å; G470-S506 PolarHBondContact O-OG 3.1Å
471R97.6Very high95.8Very high41 Ų4127.4 Ų27.416%0.15514%0.141CC..EExtended strand (participates in β ladder)trans-93.4144.4177.5-54.9-176.378.5179.516.6110.5W439 T440 L442 V466 D510 W552W439-R471 WeakPolarHBondContact CA-O 3.24Å; T440-R471 PolarHBondContact N-O 3.29Å; T440-R471 PolarHBondContact O-N 3.46Å; L442-R471 HydrophobicContact CD1-CG 3.88Å; V466-R471 HydrophobicContact CG1-CG 4Å; R471-D510 IonicContact CZ-OD1 3.43Å; R471-D510 VanDerWaalsContact CZ-OD1 3.29Å; R471-D510 IonicContact CZ-OD2 2.77Å; R471-D510 IonicContact NE-OD1 3.66Å; R471-D510 PolarHBondContact NE-OD1 2.9Å; R471-D510 IonicContact NE-OD2 3.77Å; R471-D510 PolarHBondContact NE-OD2 2.67Å; R471-D510 IonicContact NH2-OD1 3.7Å; R471-D510 PolarHBondContact NH2-OD1 3.43Å; R471-D510 IonicContact NH2-OD2 3.26Å; R471-W552 HydrophobicContact CB-CH2 4.23Å; R471-W552 HydrophobicContact CB-CZ2 3.68Å; R471-W552 VanDerWaalsContact NH1-CB 3.28Å; R471-W552 VanDerWaalsContact NH1-CG 3.29Å; R471-W552 VanDerWaalsContact NH2-CB 3.25Å
472F98.6Very high96.1Very high0 Ų026 Ų260%013%0.129CC..EExtended strand (participates in β ladder)trans-130.5132-173.4-174.1-101.9000111.5I102 T437 W439 Y474 N484 L496 L503 V507I102-F472 HydrophobicContact CG2-CD2 4.43Å; I102-F472 HydrophobicContact CG2-CE2 3.43Å; I102-F472 VanDerWaalsContact CG2-CE2 3.43Å; I102-F472 HydrophobicContact CG2-CZ 4.07Å; T437-F472 HydrophobicContact CG2-CD2 4.27Å; T437-F472 HydrophobicContact CG2-CE2 3.3Å; T437-F472 HydrophobicContact CG2-CZ 3.55Å; W439-F472 HydrophobicContact CB-CD2 4.17Å; W439-F472 HydrophobicContact CG-CD2 4.23Å; F472-Y474 HydrophobicContact CD1-CD1 4.07Å; F472-Y474 HydrophobicContact CD1-CE1 4.43Å; F472-Y474 AromaticContact CE1-CD1 3.35Å; F472-Y474 HydrophobicContact CE1-CD1 3.35Å; F472-Y474 AromaticContact CE1-CE1 3.77Å; F472-Y474 HydrophobicContact CE1-CE1 3.77Å; F472-Y474 HydrophobicContact CE1-CG 4.24Å; F472-Y474 HydrophobicContact CZ-CD1 4.08Å; F472-N484 PolarHBondContact O-ND2 3.24Å; F472-N484 VanDerWaalsContact O-ND2 3.08Å; F472-L496 HydrophobicContact CD1-CD1 4.3Å; F472-L496 HydrophobicContact CE1-CD1 3.74Å; F472-L496 HydrophobicContact CE1-CD2 4.19Å; F472-L496 HydrophobicContact CZ-CD2 4.4Å; F472-L503 HydrophobicContact CB-CD2 4.32Å; F472-L503 HydrophobicContact CD1-CB 4.39Å; F472-L503 HydrophobicContact CD2-CD1 3.95Å; F472-L503 HydrophobicContact CD2-CD2 4.23Å; F472-L503 HydrophobicContact CD2-CG 4.46Å; F472-L503 HydrophobicContact CE2-CD1 3.98Å; F472-L503 HydrophobicContact CG-CB 4.21Å; F472-L503 HydrophobicContact CG-CD1 4.46Å; F472-L503 HydrophobicContact CG-CD2 4.4Å; F472-L503 HydrophobicContact CZ-CD1 4.49Å; F472-V507 HydrophobicContact CB-CG2 4.15Å; F472-V507 HydrophobicContact CD1-CG2 3.69Å; F472-V507 HydrophobicContact CG-CG2 4.41Å
473A98.3Very high96.4Very high0 Ų023.7 Ų23.70%012%0.118CC..EExtended strand (participates in β ladder)trans-147.5145.417300000112.2T437 V438 Y483 N484 I544 W552T437-A473 CarbonylContact C-O 3.47Å; T437-A473 WeakPolarHBondContact CA-O 3.27Å; V438-A473 HydrophobicContact CG2-CB 3.67Å; V438-A473 PolarHBondContact N-O 3Å; V438-A473 PolarHBondContact O-N 3.39Å; A473-Y483 HydrophobicContact CB-CD1 3.6Å; A473-Y483 HydrophobicContact CB-CE1 4.22Å; A473-Y483 HydrophobicContact CB-CG 4.01Å; A473-N484 VanDerWaalsContact CA-OD1 3.29Å; A473-N484 WeakPolarHBondContact CA-OD1 3.44Å; A473-I544 HydrophobicContact CB-CD1 3.66Å; A473-W552 HydrophobicContact CB-CZ2 3.92Å
474Y98.4Very high96.5Very high0 Ų023.6 Ų23.60%012%0.117CC..  trans-144.2151.1173.663.4-68.5000109.5F431 F472 N484 H489 L496 M827 L830F431-Y474 HydrophobicContact CD1-CD2 4.2Å; F431-Y474 AromaticContact CE1-CD2 3.95Å; F431-Y474 HydrophobicContact CE1-CD2 3.95Å; F431-Y474 HydrophobicContact CE1-CE2 4.46Å; F472-Y474 HydrophobicContact CD1-CD1 4.07Å; F472-Y474 HydrophobicContact CD1-CE1 4.43Å; F472-Y474 AromaticContact CE1-CD1 3.35Å; F472-Y474 HydrophobicContact CE1-CD1 3.35Å; F472-Y474 AromaticContact CE1-CE1 3.77Å; F472-Y474 HydrophobicContact CE1-CE1 3.77Å; F472-Y474 HydrophobicContact CE1-CG 4.24Å; F472-Y474 HydrophobicContact CZ-CD1 4.08Å; Y474-N484 WeakPolarHBondContact CD1-OD1 3.37Å; Y474-N484 PolarHBondContact N-OD1 2.83Å; Y474-N484 PolarHBondContact O-N 3.39Å; Y474-N484 PolarHBondContact O-OD1 3.38Å; Y474-H489 AromaticContact CE1-CE1 3.98Å; Y474-H489 AromaticContact CE1-ND1 3.78Å; Y474-H489 AromaticContact CZ-ND1 3.6Å; Y474-H489 PolarHBondContact OH-CE1 3.13Å; Y474-H489 VanDerWaalsContact OH-CE1 3.28Å; Y474-H489 PolarHBondContact OH-ND1 3.31Å; Y474-L496 HydrophobicContact CD1-CD1 4.49Å; Y474-L496 HydrophobicContact CE1-CD1 3.6Å; Y474-M827 HydrophobicContact CD1-CE 4.5Å; Y474-M827 HydrophobicContact CD2-CB 4.38Å; Y474-M827 HydrophobicContact CD2-CE 3.53Å; Y474-M827 HydrophobicContact CE1-CE 4.09Å; Y474-M827 HydrophobicContact CE2-CB 3.96Å; Y474-M827 HydrophobicContact CE2-CE 3.06Å; Y474-M827 HydrophobicContact CG-CE 4.25Å; Y474-L830 HydrophobicContact CE2-CD1 4.16Å
475L98.5Very high96.7Very high0 Ų019.8 Ų19.80%09%0.086CC..BIsolated β-bridgetrans-72.5155.1-173.1-61175000111.3Y125 F431 G435 G477 M482 Y483 P547Y125-L475 HydrophobicContact CE2-CD1 3.92Å; F431-L475 VanDerWaalsContact CE1-O 3.26Å; F431-L475 WeakPolarHBondContact CE1-O 3.34Å; F431-L475 WeakPolarHBondContact CZ-O 3.18Å; G435-L475 VanDerWaalsContact O-CB 3.29Å; G435-L475 WeakPolarHBondContact O-CB 3.39Å; G435-L475 PolarHBondContact O-N 3.13Å; L475-G477 VanDerWaalsContact C-N 3.32Å; L475-M482 CarbonylContact C-O 3.57Å; L475-M482 VanDerWaalsContact CA-O 3.27Å; L475-M482 WeakPolarHBondContact CA-O 3.38Å; L475-Y483 HydrophobicContact CD2-CD1 3.71Å; L475-Y483 HydrophobicContact CD2-CD2 4.04Å; L475-Y483 HydrophobicContact CD2-CE1 3.67Å; L475-Y483 HydrophobicContact CD2-CE2 4.01Å; L475-Y483 HydrophobicContact CD2-CG 3.91Å; L475-Y483 HydrophobicContact CG-CD1 4.26Å; L475-Y483 HydrophobicContact CG-CE1 4.01Å; L475-P547 HydrophobicContact CD2-CG 4.27Å
476E98.5Very high96.8Very high12 Ų1219 Ų196%0.0568%0.082CC..SBendtrans-58.5-45.3166.2-165.4-174.5139.300111.8Y480 M482 T485 V488 Y826 M827E476-Y480 VanDerWaalsContact OE1-CD2 3.24Å; E476-Y480 WeakPolarHBondContact OE1-CD2 3.36Å; E476-M482 PolarHBondContact N-O 2.89Å; E476-M482 WeakPolarHBondContact OE2-CE 3.27Å; E476-T485 WeakPolarHBondContact CB-OG1 3.35Å; E476-T485 HydrophobicContact CG-CG2 4.18Å; E476-T485 WeakPolarHBondContact OE2-CB 3.28Å; E476-T485 VanDerWaalsContact OE2-CG2 3.24Å; E476-T485 WeakPolarHBondContact OE2-CG2 3.34Å; E476-T485 PolarHBondContact OE2-OG1 3.43Å; E476-V488 HydrophobicContact CG-CB 4.37Å; E476-V488 HydrophobicContact CG-CG1 4.47Å; E476-V488 HydrophobicContact CG-CG2 4Å; E476-Y826 HydrophobicContact CG-CE1 4.36Å; E476-Y826 HydrophobicContact CG-CE2 3.7Å; E476-Y826 WeakPolarHBondContact CG-OH 3.1Å; E476-Y826 CarbonylContact O-C 3.58Å; E476-Y826 WeakPolarHBondContact O-CA 3.5Å; E476-Y826 WeakPolarHBondContact O-CD2 3.25Å; E476-Y826 PolarHBondContact OE1-OH 3.23Å; E476-M827 HydrophobicContact CB-SD 4.38Å; E476-M827 HydrophobicContact CG-SD 4.31Å; E476-M827 PolarHBondContact O-N 2.84Å
477G96Very high96.9Very high0 Ų019.2 Ų19.20%08%0.083CC..BIsolated β-bridgetrans-167.8-179.417100000113.6L475 E479 Y480 A825L475-G477 VanDerWaalsContact C-N 3.32Å; G477-E479 VanDerWaalsContact C-N 3.32Å; G477-Y480 PolarHBondContact N-O 3.47Å; G477-Y480 VanDerWaalsContact N-O 3.12Å; G477-Y480 CarbonylContact O-C 3.59Å; G477-A825 CarbonylContact C-O 3.41Å; G477-A825 WeakPolarHBondContact CA-O 3.48Å
478Q92.8Very high97Very high8 Ų813.4 Ų13.44%0.0376%0.058CC..SBendtrans-74.5-23.2178.8-75.4-176.210.500113.4L89 Y125 Y127 D434 L824 A825L89-Q478 HydrophobicContact CD1-CB 4.13Å; Y125-Q478 HydrophobicContact CD1-CG 4.42Å; Y125-Q478 HydrophobicContact CD2-CG 4.3Å; Y125-Q478 HydrophobicContact CE1-CG 3.9Å; Y125-Q478 HydrophobicContact CE2-CG 3.78Å; Y125-Q478 PolarHBondContact OH-NE2 3.29Å; Y127-Q478 WeakPolarHBondContact OH-CB 3.45Å; D434-Q478 PolarHBondContact O-NE2 3.02Å; Q478-L824 PolarHBondContact N-O 2.66Å; Q478-A825 HydrophobicContact CB-CB 4.03Å; Q478-A825 HydrophobicContact CG-CB 3.61Å; Q478-A825 PolarHBondContact N-O 3Å
479E91Very high97.1Very high26 Ų268.6 Ų8.612%0.1214%0.035CC..SBendtrans-94.2-25.8173.2-63.8-171.193.800112.6A88 L89 G477 S823 L824A88-E479 WeakPolarHBondContact CA-OE1 3.32Å; L89-E479 HydrophobicContact CB-CG 3.88Å; L89-E479 HydrophobicContact CD1-CG 3.63Å; L89-E479 HydrophobicContact CG-CG 3.82Å; L89-E479 PolarHBondContact N-OE1 3.3Å; G477-E479 VanDerWaalsContact C-N 3.32Å; E479-S823 WeakPolarHBondContact OE2-CA 3.44Å; E479-S823 PolarHBondContact OE2-N 2.95Å; E479-L824 PolarHBondContact OE2-N 3.11Å
480Y93.6Very high97.2Very high31 Ų317 Ų712%0.1223%0.029CC..BIsolated β-bridgetrans-112.389.4-175.8-63.3-1.9000108.4F82 I83 E476 G477 M482 R822 S823 Y826F82-Y480 CarbonylContact O-C 3.5Å; F82-Y480 WeakPolarHBondContact O-CA 3.36Å; I83-Y480 HydrophobicContact CB-CD1 4.34Å; I83-Y480 HydrophobicContact CD1-CD1 4.21Å; I83-Y480 HydrophobicContact CD1-CE1 4.48Å; I83-Y480 HydrophobicContact CD1-CG 4.36Å; I83-Y480 HydrophobicContact CG1-CD1 3.68Å; I83-Y480 HydrophobicContact CG1-CE1 4.24Å; I83-Y480 HydrophobicContact CG1-CG 4.06Å; I83-Y480 HydrophobicContact CG2-CD1 4.03Å; I83-Y480 HydrophobicContact CG2-CE1 3.88Å; E476-Y480 VanDerWaalsContact OE1-CD2 3.24Å; E476-Y480 WeakPolarHBondContact OE1-CD2 3.36Å; G477-Y480 PolarHBondContact N-O 3.47Å; G477-Y480 VanDerWaalsContact N-O 3.12Å; G477-Y480 CarbonylContact O-C 3.59Å; Y480-M482 VanDerWaalsContact C-N 3.27Å; Y480-M482 HydrophobicContact CG-CE 4.41Å; Y480-M482 PolarHBondContact O-N 2.99Å; Y480-R822 VanDerWaalsContact OH-CD 3.28Å; Y480-R822 WeakPolarHBondContact OH-CD 3.4Å; Y480-R822 WeakPolarHBondContact OH-CG 3.41Å; Y480-R822 PolarHBondContact OH-NH1 2.83Å; Y480-S823 VanDerWaalsContact CD2-OG 3.24Å; Y480-S823 WeakPolarHBondContact CD2-OG 3.21Å; Y480-S823 VanDerWaalsContact CE2-CB 3.48Å; Y480-S823 WeakPolarHBondContact CE2-OG 3.4Å; Y480-S823 VanDerWaalsContact CG-OG 3.29Å; Y480-S823 VanDerWaalsContact CZ-CB 3.5Å; Y480-Y826 AromaticContact CD2-CE2 3.43Å; Y480-Y826 HydrophobicContact CD2-CE2 3.43Å; Y480-Y826 VanDerWaalsContact CD2-CE2 3.43Å; Y480-Y826 AromaticContact CD2-CZ 3.98Å; Y480-Y826 AromaticContact CE2-CE2 4Å; Y480-Y826 HydrophobicContact CE2-CE2 4Å; Y480-Y826 HydrophobicContact CG-CE2 4.16Å
481R94.3Very high97.2Very high22 Ų227 Ų78%0.0833%0.029CC..  trans-87.461.9-167.1-57.4-175.3-55.2122.522.7111.6A80 P81 F82 M124 D546 P547 D548A80-R481 PolarHBondContact O-NH2 3.46Å; P81-R481 PolarHBondContact O-NE 3.24Å; P81-R481 PolarHBondContact O-NH2 3.46Å; F82-R481 PolarHBondContact O-N 2.99Å; M124-R481 PolarHBondContact SD-NH1 3.24Å; R481-D546 IonicContact CZ-OD1 2.73Å; R481-D546 IonicContact NH1-OD1 3.68Å; R481-D546 IonicContact NH2-OD1 3.35Å; R481-D546 PolarHBondContact NH2-OD1 3.39Å; R481-D546 IonicContact NH2-OD2 3.47Å; R481-D546 PolarHBondContact NH2-OD2 3.42Å; R481-P547 HydrophobicContact CB-CG 4.1Å; R481-P547 WeakPolarHBondContact O-CD 3.5Å; R481-D548 IonicContact CZ-OD2 3.68Å; R481-D548 IonicContact NH1-OD2 3.35Å; R481-D548 PolarHBondContact NH1-OD2 3.44Å; R481-D548 IonicContact NH2-OD2 2.79Å
482M97.3Very high97.3Very high0 Ų05 Ų50%02%0.022CC..  trans-122.2131176.1-68.5154.7-70.700108.5F82 I83 L475 E476 Y480 T485 D543 A557 Y558F82-M482 HydrophobicContact CB-CG 4.24Å; F82-M482 HydrophobicContact CD2-CE 4.07Å; F82-M482 HydrophobicContact CD2-CG 4.32Å; F82-M482 HydrophobicContact CD2-SD 3.64Å; F82-M482 HydrophobicContact CE2-SD 4.31Å; I83-M482 HydrophobicContact CD1-CE 3.98Å; I83-M482 HydrophobicContact CG1-CE 3.9Å; L475-M482 CarbonylContact C-O 3.57Å; L475-M482 VanDerWaalsContact CA-O 3.27Å; L475-M482 WeakPolarHBondContact CA-O 3.38Å; E476-M482 PolarHBondContact N-O 2.89Å; E476-M482 WeakPolarHBondContact OE2-CE 3.27Å; Y480-M482 VanDerWaalsContact C-N 3.27Å; Y480-M482 HydrophobicContact CG-CE 4.41Å; Y480-M482 PolarHBondContact O-N 2.99Å; M482-T485 VanDerWaalsContact CB-OG1 3.28Å; M482-T485 WeakPolarHBondContact CB-OG1 3.48Å; M482-D543 HydrophobicContact CB-CB 3.81Å; M482-D543 HydrophobicContact CG-CB 4.45Å; M482-A557 HydrophobicContact CG-CB 4.14Å; M482-Y558 HydrophobicContact SD-CD2 3.97Å; M482-Y558 HydrophobicContact SD-CG 4.38Å
483Y98.6Very high97.3Very high0 Ų05 Ų50%02%0.022CC..BIsolated β-bridgetrans-81.9136.8-179.9-82.1-67.2000111.7G123 F364 G436 V438 A473 L475 T485 D543 I544 G545 P547 P551G123-Y483 WeakPolarHBondContact CA-OH 3.44Å; G123-Y483 PolarHBondContact N-OH 3.37Å; F364-Y483 HydrophobicContact CE1-CE2 4.07Å; G436-Y483 WeakPolarHBondContact O-CE1 3.43Å; G436-Y483 PolarHBondContact O-OH 3.4Å; V438-Y483 WeakPolarHBondContact CG1-OH 3.5Å; V438-Y483 HydrophobicContact CG2-CE1 3.95Å; A473-Y483 HydrophobicContact CB-CD1 3.6Å; A473-Y483 HydrophobicContact CB-CE1 4.22Å; A473-Y483 HydrophobicContact CB-CG 4.01Å; L475-Y483 HydrophobicContact CD2-CD1 3.71Å; L475-Y483 HydrophobicContact CD2-CD2 4.04Å; L475-Y483 HydrophobicContact CD2-CE1 3.67Å; L475-Y483 HydrophobicContact CD2-CE2 4.01Å; L475-Y483 HydrophobicContact CD2-CG 3.91Å; L475-Y483 HydrophobicContact CG-CD1 4.26Å; L475-Y483 HydrophobicContact CG-CE1 4.01Å; Y483-T485 PolarHBondContact O-N 2.77Å; Y483-D543 WeakPolarHBondContact O-CB 3.46Å; Y483-I544 VanDerWaalsContact O-CG1 3.26Å; Y483-I544 WeakPolarHBondContact O-CG1 3.39Å; Y483-I544 PolarHBondContact O-N 3.37Å; Y483-G545 PolarHBondContact N-O 3.13Å; Y483-P547 HydrophobicContact CE2-CB 3.82Å; Y483-P547 HydrophobicContact CE2-CG 4.35Å; Y483-P551 HydrophobicContact CD2-CB 3.9Å; Y483-P551 HydrophobicContact CD2-CG 3.56Å; Y483-P551 HydrophobicContact CE2-CB 4.33Å; Y483-P551 HydrophobicContact CE2-CG 3.63Å
484N98.4Very high97.3Very high0 Ų05 Ų50%02%0.022CC..THydrogen-bonded Turntrans45.445.9178.3-59.1-14.8000112.4F472 A473 Y474 Y486 I544F472-N484 PolarHBondContact O-ND2 3.24Å; F472-N484 VanDerWaalsContact O-ND2 3.08Å; A473-N484 VanDerWaalsContact CA-OD1 3.29Å; A473-N484 WeakPolarHBondContact CA-OD1 3.44Å; Y474-N484 WeakPolarHBondContact CD1-OD1 3.37Å; Y474-N484 PolarHBondContact N-OD1 2.83Å; Y474-N484 PolarHBondContact O-N 3.39Å; Y474-N484 PolarHBondContact O-OD1 3.38Å; N484-Y486 WeakPolarHBondContact O-CA 3.13Å; N484-Y486 PolarHBondContact O-N 2.69Å; N484-I544 HydrophobicContact CB-CD1 4.29Å; N484-I544 HydrophobicContact CB-CG1 4.09Å; N484-I544 WeakPolarHBondContact ND2-CD1 3.44Å
485T98.6Very high97.3Very high0 Ų05 Ų50%02%0.022CC..  trans-53.9111.4173.9-60.90000109.1E476 M482 Y483 D487 V488 H489 H542E476-T485 WeakPolarHBondContact CB-OG1 3.35Å; E476-T485 HydrophobicContact CG-CG2 4.18Å; E476-T485 WeakPolarHBondContact OE2-CB 3.28Å; E476-T485 VanDerWaalsContact OE2-CG2 3.24Å; E476-T485 WeakPolarHBondContact OE2-CG2 3.34Å; E476-T485 PolarHBondContact OE2-OG1 3.43Å; M482-T485 VanDerWaalsContact CB-OG1 3.28Å; M482-T485 WeakPolarHBondContact CB-OG1 3.48Å; Y483-T485 PolarHBondContact O-N 2.77Å; T485-D487 WeakPolarHBondContact CG2-OD1 3.32Å; T485-V488 HydrophobicContact CG2-CB 4.39Å; T485-V488 HydrophobicContact CG2-CG2 3.77Å; T485-V488 PolarHBondContact O-N 3Å; T485-H489 WeakPolarHBondContact O-CB 3.23Å; T485-H489 PolarHBondContact O-N 2.96Å; T485-H542 CarbonylContact C-O 3.56Å; T485-H542 VanDerWaalsContact CA-O 3.25Å; T485-H542 WeakPolarHBondContact CA-O 3.48Å; T485-H542 WeakPolarHBondContact CG2-CE1 3.47Å; T485-H542 WeakPolarHBondContact CG2-NE2 3.17Å
486Y98.5Very high97.3Very high0 Ų05.1 Ų5.10%02%0.022CC..Hα-helixtrans-80.8-33.7-151.7-164.1-101.3000112.3N484 V488 H489 F490 Q508 I511 V540 H542 L569 F573 Q576N484-Y486 WeakPolarHBondContact O-CA 3.13Å; N484-Y486 PolarHBondContact O-N 2.69Å; Y486-V488 PolarHBondContact O-N 3.48Å; Y486-H489 PolarHBondContact O-N 2.94Å; Y486-F490 PolarHBondContact O-N 2.94Å; Y486-F490 VanDerWaalsContact O-N 3.14Å; Y486-Q508 PolarHBondContact OH-NE2 3.08Å; Y486-Q508 PolarHBondContact OH-OE1 3.1Å; Y486-I511 HydrophobicContact CD2-CB 4.44Å; Y486-I511 HydrophobicContact CD2-CD1 3.74Å; Y486-I511 HydrophobicContact CD2-CG1 3.71Å; Y486-I511 HydrophobicContact CD2-CG2 4.07Å; Y486-I511 HydrophobicContact CE1-CG2 4.5Å; Y486-I511 HydrophobicContact CE2-CB 4.08Å; Y486-I511 HydrophobicContact CE2-CD1 4.22Å; Y486-I511 HydrophobicContact CE2-CG1 3.67Å; Y486-I511 HydrophobicContact CE2-CG2 3.79Å; Y486-I511 HydrophobicContact CG-CD1 4.45Å; Y486-V540 HydrophobicContact CD1-CG1 3.43Å; Y486-V540 VanDerWaalsContact CD1-CG1 3.43Å; Y486-V540 HydrophobicContact CE1-CG1 3.86Å; Y486-V540 HydrophobicContact CG-CG1 3.9Å; Y486-H542 PolarHBondContact N-O 2.74Å; Y486-L569 HydrophobicContact CD1-CD2 4.49Å; Y486-F573 HydrophobicContact CE1-CB 3.69Å; Y486-F573 HydrophobicContact CE1-CD2 4.23Å; Y486-F573 HydrophobicContact CE1-CG 4.49Å; Y486-F573 AromaticContact CZ-CD2 3.89Å; Y486-F573 WeakPolarHBondContact OH-CA 3.31Å; Y486-F573 VanDerWaalsContact OH-CD2 3.29Å; Y486-F573 WeakPolarHBondContact OH-CD2 3.32Å; Y486-Q576 PolarHBondContact OH-NE2 3.45Å
487D98.5Very high97.3Very high4 Ų44.8 Ų4.82%0.0212%0.021CC..Hα-helixtrans-65.8-26.7172.962.9-69.9000112.4T485 H542 L569 K572 T624T485-D487 WeakPolarHBondContact CG2-OD1 3.32Å; D487-H542 IonicContact OD1-CD2 2.73Å; D487-H542 PolarHBondContact OD1-CD2 3.24Å; D487-H542 IonicContact OD1-NE2 3.75Å; D487-H542 PolarHBondContact OD1-NE2 3.34Å; D487-L569 HydrophobicContact CB-CD2 3.74Å; D487-K572 HydrophobicContact CB-CD 4.15Å; D487-K572 PolarHBondContact O-NZ 3.1Å; D487-T624 WeakPolarHBondContact OD2-CB 3.46Å; D487-T624 PolarHBondContact OD2-OG1 3.37Å
488V98.6Very high97.5Very high1 Ų16.6 Ų6.61%0.0063%0.029CC..Hα-helixtrans-86.9-38.8174.2-168.30000111.3E476 T485 Y486 F490 Y491 A492 Y826 M827 R828E476-V488 HydrophobicContact CG-CB 4.37Å; E476-V488 HydrophobicContact CG-CG1 4.47Å; E476-V488 HydrophobicContact CG-CG2 4Å; T485-V488 HydrophobicContact CG2-CB 4.39Å; T485-V488 HydrophobicContact CG2-CG2 3.77Å; T485-V488 PolarHBondContact O-N 3Å; Y486-V488 PolarHBondContact O-N 3.48Å; V488-F490 PolarHBondContact O-N 3.43Å; V488-F490 VanDerWaalsContact O-N 3.17Å; V488-Y491 PolarHBondContact O-N 3.44Å; V488-A492 PolarHBondContact O-N 3.37Å; V488-Y826 HydrophobicContact CG1-CD1 4.38Å; V488-Y826 HydrophobicContact CG1-CE1 3.67Å; V488-M827 HydrophobicContact CB-CG 4.06Å; V488-M827 HydrophobicContact CB-SD 3.67Å; V488-M827 HydrophobicContact CG1-CG 3.3Å; V488-M827 HydrophobicContact CG1-SD 3.64Å; V488-R828 HydrophobicContact CG1-CB 3.69Å; V488-R828 HydrophobicContact CG1-CG 3.87Å
489H98.6Very high97.7Very high1 Ų16.7 Ų6.71%0.0053%0.03CC..Hα-helixtrans-54.1-33.4174.2-175.672000112Y474 T485 Y486 Y491 A492 S493 Q576Y474-H489 AromaticContact CE1-CE1 3.98Å; Y474-H489 AromaticContact CE1-ND1 3.78Å; Y474-H489 AromaticContact CZ-ND1 3.6Å; Y474-H489 PolarHBondContact OH-CE1 3.13Å; Y474-H489 VanDerWaalsContact OH-CE1 3.28Å; Y474-H489 PolarHBondContact OH-ND1 3.31Å; T485-H489 WeakPolarHBondContact O-CB 3.23Å; T485-H489 PolarHBondContact O-N 2.96Å; Y486-H489 PolarHBondContact O-N 2.94Å; H489-Y491 PolarHBondContact O-N 3.26Å; H489-Y491 VanDerWaalsContact O-N 3.12Å; H489-A492 PolarHBondContact O-N 2.79Å; H489-S493 WeakPolarHBondContact NE2-CB 3.39Å; H489-S493 WeakPolarHBondContact O-CA 3.25Å; H489-S493 WeakPolarHBondContact O-CB 3.46Å; H489-S493 PolarHBondContact O-N 2.93Å; H489-S493 PolarHBondContact O-OG 3.32Å; H489-S493 VanDerWaalsContact O-OG 3.05Å; H489-Q576 PolarHBondContact CD2-OE1 2.7Å; H489-Q576 VanDerWaalsContact CD2-OE1 3.27Å
490F98.7Very high98.1Very high0 Ų05.5 Ų5.50%03%0.025CC..Hα-helixtrans-45.3-42.3171.6175.9-102000114.2Y486 V488 S493 K572 L575 Q576 W707 F708Y486-F490 PolarHBondContact O-N 2.94Å; Y486-F490 VanDerWaalsContact O-N 3.14Å; V488-F490 PolarHBondContact O-N 3.43Å; V488-F490 VanDerWaalsContact O-N 3.17Å; F490-S493 PolarHBondContact O-OG 2.93Å; F490-K572 HydrophobicContact CB-CB 4.3Å; F490-K572 HydrophobicContact CB-CD 3.78Å; F490-K572 HydrophobicContact CB-CG 4.07Å; F490-K572 HydrophobicContact CD1-CD 4.4Å; F490-K572 HydrophobicContact CD1-CG 4.41Å; F490-K572 HydrophobicContact CD2-CB 3.75Å; F490-K572 HydrophobicContact CD2-CD 4.17Å; F490-K572 HydrophobicContact CD2-CG 3.52Å; F490-K572 HydrophobicContact CE2-CB 4.38Å; F490-K572 HydrophobicContact CE2-CG 3.94Å; F490-K572 HydrophobicContact CG-CB 4.25Å; F490-K572 HydrophobicContact CG-CD 3.88Å; F490-K572 HydrophobicContact CG-CG 3.75Å; F490-L575 HydrophobicContact CE2-CB 4.34Å; F490-L575 HydrophobicContact CE2-CD1 4.12Å; F490-Q576 HydrophobicContact CD2-CG 4.11Å; F490-W707 HydrophobicContact CD1-CZ3 4.23Å; F490-W707 HydrophobicContact CE1-CE3 4.12Å; F490-W707 AromaticContact CE1-CZ3 3.6Å; F490-W707 HydrophobicContact CE1-CZ3 3.6Å; F490-W707 HydrophobicContact CZ-CZ3 4.31Å; F490-F708 AromaticContact CD2-CD2 3.99Å; F490-F708 HydrophobicContact CD2-CD2 3.99Å; F490-F708 AromaticContact CD2-CE2 3.58Å; F490-F708 HydrophobicContact CD2-CE2 3.58Å; F490-F708 HydrophobicContact CD2-CZ 4.05Å; F490-F708 AromaticContact CE1-CD2 3.97Å; F490-F708 HydrophobicContact CE1-CD2 3.97Å; F490-F708 HydrophobicContact CE1-CE2 4.27Å; F490-F708 HydrophobicContact CE2-CB 4.38Å; F490-F708 HydrophobicContact CE2-CD1 4.27Å; F490-F708 AromaticContact CE2-CD2 3.13Å; F490-F708 HydrophobicContact CE2-CD2 3.13Å; F490-F708 HydrophobicContact CE2-CE1 4.32Å; F490-F708 AromaticContact CE2-CE2 3.2Å; F490-F708 HydrophobicContact CE2-CE2 3.2Å; F490-F708 AromaticContact CE2-CG 3.67Å; F490-F708 HydrophobicContact CE2-CG 3.67Å; F490-F708 AromaticContact CE2-CZ 3.82Å; F490-F708 HydrophobicContact CE2-CZ 3.82Å; F490-F708 HydrophobicContact CG-CE2 4.28Å; F490-F708 HydrophobicContact CZ-CB 4.12Å; F490-F708 AromaticContact CZ-CD2 3.12Å; F490-F708 HydrophobicContact CZ-CD2 3.12Å; F490-F708 AromaticContact CZ-CE2 3.6Å; F490-F708 HydrophobicContact CZ-CE2 3.6Å; F490-F708 AromaticContact CZ-CG 3.78Å; F490-F708 HydrophobicContact CZ-CG 3.78Å
491Y98.8Very high98.4Very high0 Ų05 Ų50%03%0.025CC..Hα-helixtrans-84.1-38.6178.3-58.5-97.2000111.5V488 H489 F494 Y636 D701 W707 V773 R828 S831V488-Y491 PolarHBondContact O-N 3.44Å; H489-Y491 PolarHBondContact O-N 3.26Å; H489-Y491 VanDerWaalsContact O-N 3.12Å; Y491-F494 WeakPolarHBondContact O-CD2 3.4Å; Y491-Y636 PolarHBondContact OH-OH 2.9Å; Y491-D701 PolarHBondContact OH-OD2 2.78Å; Y491-W707 AromaticContact CD1-CH2 3.87Å; Y491-W707 HydrophobicContact CD1-CH2 3.87Å; Y491-W707 AromaticContact CD1-CZ3 3.71Å; Y491-W707 HydrophobicContact CD1-CZ3 3.71Å; Y491-W707 HydrophobicContact CE1-CH2 4.48Å; Y491-W707 AromaticContact CE1-CZ3 3.87Å; Y491-W707 HydrophobicContact CE1-CZ3 3.87Å; Y491-V773 HydrophobicContact CE1-CG2 4.06Å; Y491-R828 VanDerWaalsContact CB-CG 3.49Å; Y491-R828 HydrophobicContact CD1-CG 4.45Å; Y491-R828 HydrophobicContact CD2-CG 3.87Å; Y491-R828 HydrophobicContact CG-CG 3.7Å; Y491-S831 VanDerWaalsContact O-CA 3.25Å; Y491-S831 WeakPolarHBondContact O-CA 3.2Å; Y491-S831 VanDerWaalsContact O-CB 3.23Å; Y491-S831 WeakPolarHBondContact O-CB 3.46Å
492A98.4Very high98.6Very high0 Ų07 Ų70%04%0.035CC..Hα-helixtrans-75.4-25.5-175.300000113.8V488 H489 F494 A495 M827 L830V488-A492 PolarHBondContact O-N 3.37Å; H489-A492 PolarHBondContact O-N 2.79Å; A492-F494 PolarHBondContact O-N 3.33Å; A492-F494 VanDerWaalsContact O-N 3.11Å; A492-A495 PolarHBondContact O-N 3.13Å; A492-M827 HydrophobicContact CB-CB 4.26Å; A492-M827 HydrophobicContact CB-CG 4.08Å; A492-M827 VanDerWaalsContact CB-O 3.25Å; A492-M827 WeakPolarHBondContact CB-O 3.49Å; A492-L830 HydrophobicContact CB-CB 4Å; A492-L830 HydrophobicContact CB-CD1 4.16Å
493S98.4Very high98.6Very high0 Ų07 Ų70%04%0.035CC..Hα-helixtrans-68.1-15.3-166.358.10000114.2H489 F490 A495 L496 I497 Q576 R579H489-S493 WeakPolarHBondContact NE2-CB 3.39Å; H489-S493 WeakPolarHBondContact O-CA 3.25Å; H489-S493 WeakPolarHBondContact O-CB 3.46Å; H489-S493 PolarHBondContact O-N 2.93Å; H489-S493 PolarHBondContact O-OG 3.32Å; H489-S493 VanDerWaalsContact O-OG 3.05Å; F490-S493 PolarHBondContact O-OG 2.93Å; S493-A495 VanDerWaalsContact C-N 3.31Å; S493-A495 PolarHBondContact O-N 3.43Å; S493-L496 PolarHBondContact O-N 2.91Å; S493-I497 WeakPolarHBondContact O-CG2 3.25Å; S493-I497 PolarHBondContact O-N 3.01Å; S493-Q576 PolarHBondContact OG-OE1 2.82Å; S493-R579 VanDerWaalsContact OG-CZ 3.3Å; S493-R579 PolarHBondContact OG-NH1 2.81Å; S493-R579 PolarHBondContact OG-NH2 2.94Å
494F98.8Very high98.6Very high1 Ų17.1 Ų7.10%0.0044%0.035CC..Hα-helixtrans-56.1-43.6172.9-72.3-91.8000112.4Y491 A492 L496 M498 W707 F708 A711 W833 A834 L837Y491-F494 WeakPolarHBondContact O-CD2 3.4Å; A492-F494 PolarHBondContact O-N 3.33Å; A492-F494 VanDerWaalsContact O-N 3.11Å; F494-L496 VanDerWaalsContact C-N 3.33Å; F494-L496 PolarHBondContact O-N 3.24Å; F494-M498 VanDerWaalsContact O-CB 3.28Å; F494-M498 WeakPolarHBondContact O-CB 3.5Å; F494-M498 WeakPolarHBondContact O-CG 3.35Å; F494-M498 PolarHBondContact O-N 2.96Å; F494-M498 VanDerWaalsContact O-N 3.09Å; F494-W707 HydrophobicContact CD2-CH2 4.44Å; F494-W707 HydrophobicContact CD2-CZ2 4.2Å; F494-W707 HydrophobicContact CE1-CZ2 4.48Å; F494-W707 AromaticContact CE2-CH2 3.59Å; F494-W707 HydrophobicContact CE2-CH2 3.59Å; F494-W707 AromaticContact CE2-CZ2 3.34Å; F494-W707 HydrophobicContact CE2-CZ2 3.34Å; F494-W707 HydrophobicContact CZ-CH2 4.13Å; F494-W707 AromaticContact CZ-CZ2 3.51Å; F494-W707 HydrophobicContact CZ-CZ2 3.51Å; F494-F708 HydrophobicContact CE2-CD2 4.41Å; F494-F708 AromaticContact CE2-CE2 3.78Å; F494-F708 HydrophobicContact CE2-CE2 3.78Å; F494-F708 HydrophobicContact CZ-CD2 4.13Å; F494-F708 AromaticContact CZ-CE2 3.74Å; F494-F708 HydrophobicContact CZ-CE2 3.74Å; F494-F708 HydrophobicContact CZ-CZ 4.37Å; F494-A711 HydrophobicContact CE1-CB 3.74Å; F494-A711 HydrophobicContact CZ-CB 3.94Å; F494-W833 HydrophobicContact CB-CB 4.03Å; F494-A834 HydrophobicContact CB-CB 4.3Å; F494-A834 HydrophobicContact CD1-CB 3.7Å; F494-A834 HydrophobicContact CD2-CB 3.85Å; F494-A834 HydrophobicContact CE1-CB 3.89Å; F494-A834 HydrophobicContact CE2-CB 4.04Å; F494-A834 HydrophobicContact CG-CB 3.67Å; F494-A834 HydrophobicContact CZ-CB 4.06Å; F494-L837 HydrophobicContact CD1-CD2 3.84Å; F494-L837 HydrophobicContact CE1-CD2 3.71Å
495A98.6Very high98.7Very high0 Ų07.1 Ų7.10%04%0.035CC..Hα-helixtrans-61-43.7178.100000111.5L429 A492 S493 L499 L830 W833L429-A495 HydrophobicContact CD2-CB 3.86Å; A492-A495 PolarHBondContact O-N 3.13Å; S493-A495 VanDerWaalsContact C-N 3.31Å; S493-A495 PolarHBondContact O-N 3.43Å; A495-L499 VanDerWaalsContact O-CB 3.27Å; A495-L499 WeakPolarHBondContact O-CB 3.48Å; A495-L499 WeakPolarHBondContact O-CG 3.4Å; A495-L499 PolarHBondContact O-N 3.2Å; A495-L499 VanDerWaalsContact O-N 3.12Å; A495-L830 HydrophobicContact CB-CB 4.09Å; A495-L830 HydrophobicContact CB-CD2 4.12Å; A495-W833 HydrophobicContact CB-CB 4.18Å; A495-W833 HydrophobicContact CB-CG 3.92Å
496L98.6Very high98.6Very high1 Ų17.1 Ų7.11%0.0054%0.035CC..Hα-helixtrans-71.4-47.8-179.8-66.4-179.2000112.3V432 F472 Y474 S493 F494 M498 L499 W500 A504V432-L496 HydrophobicContact CG1-CD2 3.94Å; V432-L496 HydrophobicContact CG2-CD2 4.38Å; F472-L496 HydrophobicContact CD1-CD1 4.3Å; F472-L496 HydrophobicContact CE1-CD1 3.74Å; F472-L496 HydrophobicContact CE1-CD2 4.19Å; F472-L496 HydrophobicContact CZ-CD2 4.4Å; Y474-L496 HydrophobicContact CD1-CD1 4.49Å; Y474-L496 HydrophobicContact CE1-CD1 3.6Å; S493-L496 PolarHBondContact O-N 2.91Å; F494-L496 VanDerWaalsContact C-N 3.33Å; F494-L496 PolarHBondContact O-N 3.24Å; L496-M498 VanDerWaalsContact C-N 3.26Å; L496-M498 PolarHBondContact O-N 3.46Å; L496-L499 PolarHBondContact O-N 3.21Å; L496-W500 HydrophobicContact CD2-CE3 4.13Å; L496-W500 CarbonylContact O-C 3.14Å; L496-W500 VanDerWaalsContact O-CA 3.28Å; L496-W500 WeakPolarHBondContact O-CA 3.47Å; L496-W500 PolarHBondContact O-N 3.39Å; L496-A504 HydrophobicContact CB-CB 3.91Å
497I98.8Very high98.6Very high5 Ų57.1 Ų7.13%0.0264%0.035CC..Hα-helixtrans-66.2-32.1-176.7-167.263.2000111.9S493 P501 A504 L505 D580 L583 T584S493-I497 WeakPolarHBondContact O-CG2 3.25Å; S493-I497 PolarHBondContact O-N 3.01Å; I497-P501 HydrophobicContact CD1-CB 4.2Å; I497-P501 WeakPolarHBondContact O-CB 3.31Å; I497-A504 HydrophobicContact CB-CB 4.05Å; I497-A504 HydrophobicContact CD1-CB 3.85Å; I497-L505 HydrophobicContact CD1-CD2 4.38Å; I497-D580 HydrophobicContact CD1-CB 3.75Å; I497-D580 HydrophobicContact CG1-CB 4.26Å; I497-D580 WeakPolarHBondContact CG1-OD1 3.42Å; I497-L583 HydrophobicContact CB-CD1 4.5Å; I497-L583 HydrophobicContact CG1-CB 4.28Å; I497-L583 HydrophobicContact CG1-CD1 3.91Å; I497-L583 HydrophobicContact CG2-CD1 3.72Å; I497-T584 HydrophobicContact CD1-CG2 3.8Å
498M98.7Very high98.6Very high38 Ų387 Ų719%0.1873%0.034CC..Hα-helixtrans-77.3-37.5178.2-67.4176.270.600112.8F494 L496 W833 Q836 L837F494-M498 VanDerWaalsContact O-CB 3.28Å; F494-M498 WeakPolarHBondContact O-CB 3.5Å; F494-M498 WeakPolarHBondContact O-CG 3.35Å; F494-M498 PolarHBondContact O-N 2.96Å; F494-M498 VanDerWaalsContact O-N 3.09Å; L496-M498 VanDerWaalsContact C-N 3.26Å; L496-M498 PolarHBondContact O-N 3.46Å; M498-W833 HydrophobicContact CB-CE3 4.34Å; M498-W833 HydrophobicContact CE-CE3 3.87Å; M498-W833 HydrophobicContact CE-CZ3 4.21Å; M498-W833 HydrophobicContact SD-CB 4.33Å; M498-W833 HydrophobicContact SD-CE3 3.99Å; M498-W833 VanDerWaalsContact SD-O 3.41Å; M498-Q836 HydrophobicContact CE-CB 4.3Å; M498-Q836 HydrophobicContact CE-CG 4.24Å; M498-L837 HydrophobicContact CE-CB 4.11Å; M498-L837 HydrophobicContact CE-CD1 4.47Å; M498-L837 HydrophobicContact SD-CB 3.87Å; M498-L837 HydrophobicContact SD-CD1 4.5Å
499L98.8Very high98.6Very high11 Ų117.3 Ų7.36%0.0584%0.035CC..Hα-helixtrans-109.1-33.9-169.7-57.5175.7000114.2P203 H204 W407 L429 A495 L496 P501 W833P203-L499 CarbonylContact C-O 3.57Å; P203-L499 WeakPolarHBondContact CA-O 3.29Å; P203-L499 HydrophobicContact CB-CB 4.02Å; P203-L499 HydrophobicContact CB-CD2 3.96Å; P203-L499 HydrophobicContact CG-CB 4.24Å; P203-L499 HydrophobicContact CG-CD2 3.84Å; P203-L499 HydrophobicContact CG-CG 4.46Å; H204-L499 PolarHBondContact N-O 3.06Å; W407-L499 HydrophobicContact CZ3-CD2 4.25Å; L429-L499 HydrophobicContact CD1-CD1 3.71Å; L429-L499 HydrophobicContact CD2-CD1 3.67Å; L429-L499 HydrophobicContact CG-CD1 4.34Å; A495-L499 VanDerWaalsContact O-CB 3.27Å; A495-L499 WeakPolarHBondContact O-CB 3.48Å; A495-L499 WeakPolarHBondContact O-CG 3.4Å; A495-L499 PolarHBondContact O-N 3.2Å; A495-L499 VanDerWaalsContact O-N 3.12Å; L496-L499 PolarHBondContact O-N 3.21Å; L499-P501 VanDerWaalsContact C-CD 3.48Å; L499-W833 HydrophobicContact CD1-CD2 4.11Å; L499-W833 HydrophobicContact CD1-CE3 4.23Å; L499-W833 HydrophobicContact CD1-CH2 3.88Å; L499-W833 HydrophobicContact CD1-CZ2 3.71Å; L499-W833 HydrophobicContact CD1-CZ3 4.12Å; L499-W833 HydrophobicContact CD2-CE3 4.32Å; L499-W833 HydrophobicContact CD2-CH2 3.72Å; L499-W833 HydrophobicContact CD2-CZ2 4.41Å; L499-W833 HydrophobicContact CD2-CZ3 3.65Å; L499-W833 HydrophobicContact CG-CE3 4.24Å; L499-W833 HydrophobicContact CG-CH2 4.21Å; L499-W833 HydrophobicContact CG-CZ3 4.05Å
500W98.8Very high98.5Very high1 Ų17.3 Ų7.30%0.0044%0.036CC..  trans-132.960.8177.7-61.1-78.7000110.9I102 V201 I202 Y206 L429 V432 L496 K502 L503 A504I102-W500 HydrophobicContact CD1-CD2 3.94Å; I102-W500 HydrophobicContact CD1-CE3 4.4Å; I102-W500 HydrophobicContact CD1-CG 4.43Å; I102-W500 HydrophobicContact CD1-CH2 4.28Å; I102-W500 HydrophobicContact CD1-CZ2 3.81Å; V201-W500 HydrophobicContact CG1-CH2 3.69Å; V201-W500 HydrophobicContact CG1-CZ2 3.44Å; V201-W500 VanDerWaalsContact CG1-CZ2 3.44Å; I202-W500 PolarHBondContact O-NE1 2.94Å; Y206-W500 HydrophobicContact CE1-CB 4.11Å; L429-W500 HydrophobicContact CD2-CZ3 4.34Å; V432-W500 HydrophobicContact CB-CZ3 4.34Å; V432-W500 HydrophobicContact CG1-CE3 4.17Å; V432-W500 HydrophobicContact CG1-CH2 4.48Å; V432-W500 HydrophobicContact CG1-CZ3 3.93Å; V432-W500 HydrophobicContact CG2-CZ3 4.12Å; L496-W500 HydrophobicContact CD2-CE3 4.13Å; L496-W500 CarbonylContact O-C 3.14Å; L496-W500 VanDerWaalsContact O-CA 3.28Å; L496-W500 WeakPolarHBondContact O-CA 3.47Å; L496-W500 PolarHBondContact O-N 3.39Å; W500-K502 PolarHBondContact O-N 2.98Å; W500-L503 HydrophobicContact CB-CB 4.22Å; W500-L503 HydrophobicContact CB-CD1 3.95Å; W500-L503 HydrophobicContact CB-CG 4.12Å; W500-L503 HydrophobicContact CG-CD1 4.31Å; W500-L503 WeakPolarHBondContact O-CB 3.21Å; W500-L503 PolarHBondContact O-N 3.36Å; W500-A504 PolarHBondContact O-N 3.09Å
501P98.8Very high98.5Very high19 Ų197.3 Ų7.312%0.1234%0.036CC..Hα-helixtrans-54.4-34.6-172.317-31.6000113.8Y206 I497 L499 L503 A504 L505 T584Y206-P501 WeakPolarHBondContact OH-CD 3.42Å; I497-P501 HydrophobicContact CD1-CB 4.2Å; I497-P501 WeakPolarHBondContact O-CB 3.31Å; L499-P501 VanDerWaalsContact C-CD 3.48Å; P501-L503 VanDerWaalsContact C-N 3.3Å; P501-L503 PolarHBondContact O-N 2.92Å; P501-A504 PolarHBondContact O-N 2.69Å; P501-L505 WeakPolarHBondContact O-CG 3.46Å; P501-L505 PolarHBondContact O-N 3.01Å; P501-T584 HydrophobicContact CB-CG2 4.04Å
502K98.6Very high98.5Very high66 Ų667.3 Ų7.329%0.2874%0.036SC..Hα-helixtrans-65.7-29.8177-53.3-61.2-178.4-175.50113.5Y206 L465 Y469 W500 S506Y206-K502 HydrophobicContact CE1-CB 3.77Å; Y206-K502 HydrophobicContact CE1-CG 4.27Å; Y206-K502 HydrophobicContact CE2-CB 4.3Å; Y206-K502 HydrophobicContact CE2-CG 3.91Å; Y206-K502 WeakPolarHBondContact OH-CG 3.35Å; Y206-K502 PolarHBondContact OH-N 2.89Å; L465-K502 HydrophobicContact CD1-CD 3.92Å; L465-K502 WeakPolarHBondContact CD2-O 3.25Å; Y469-K502 HydrophobicContact CD1-CB 3.66Å; Y469-K502 HydrophobicContact CD1-CG 4.1Å; Y469-K502 HydrophobicContact CD2-CB 3.72Å; Y469-K502 HydrophobicContact CD2-CD 4.25Å; Y469-K502 HydrophobicContact CD2-CG 4.03Å; Y469-K502 HydrophobicContact CE1-CB 3.92Å; Y469-K502 HydrophobicContact CE1-CG 3.81Å; Y469-K502 HydrophobicContact CE2-CB 4.01Å; Y469-K502 HydrophobicContact CE2-CD 3.86Å; Y469-K502 HydrophobicContact CE2-CG 3.77Å; Y469-K502 HydrophobicContact CG-CB 3.56Å; Y469-K502 HydrophobicContact CG-CG 4.22Å; W500-K502 PolarHBondContact O-N 2.98Å; K502-S506 WeakPolarHBondContact O-CB 3.4Å; K502-S506 PolarHBondContact O-N 2.85Å; K502-S506 VanDerWaalsContact O-N 3.12Å
503L98.7Very high98.4Very high0 Ų07.3 Ų7.30%04%0.036CC..Hα-helixtrans-74.8-41.6171.8-61-176.7000111.4I102 Y206 W439 F472 W500 P501 L505 S506 V507I102-L503 HydrophobicContact CG2-CD1 4.41Å; Y206-L503 HydrophobicContact CD1-CG 4.32Å; Y206-L503 HydrophobicContact CE1-CG 4.13Å; W439-L503 HydrophobicContact CD2-CD2 4.14Å; W439-L503 HydrophobicContact CE3-CD1 4.42Å; W439-L503 HydrophobicContact CH2-CD1 4.35Å; W439-L503 HydrophobicContact CH2-CD2 4.16Å; W439-L503 HydrophobicContact CZ2-CD2 3.57Å; W439-L503 HydrophobicContact CZ3-CD1 4.29Å; F472-L503 HydrophobicContact CB-CD2 4.32Å; F472-L503 HydrophobicContact CD1-CB 4.39Å; F472-L503 HydrophobicContact CD2-CD1 3.95Å; F472-L503 HydrophobicContact CD2-CD2 4.23Å; F472-L503 HydrophobicContact CD2-CG 4.46Å; F472-L503 HydrophobicContact CE2-CD1 3.98Å; F472-L503 HydrophobicContact CG-CB 4.21Å; F472-L503 HydrophobicContact CG-CD1 4.46Å; F472-L503 HydrophobicContact CG-CD2 4.4Å; F472-L503 HydrophobicContact CZ-CD1 4.49Å; W500-L503 HydrophobicContact CB-CB 4.22Å; W500-L503 HydrophobicContact CB-CD1 3.95Å; W500-L503 HydrophobicContact CB-CG 4.12Å; W500-L503 HydrophobicContact CG-CD1 4.31Å; W500-L503 WeakPolarHBondContact O-CB 3.21Å; W500-L503 PolarHBondContact O-N 3.36Å; P501-L503 VanDerWaalsContact C-N 3.3Å; P501-L503 PolarHBondContact O-N 2.92Å; L503-L505 PolarHBondContact O-N 2.78Å; L503-S506 WeakPolarHBondContact O-CB 3.45Å; L503-S506 PolarHBondContact O-N 3.16Å; L503-S506 VanDerWaalsContact O-N 3.17Å; L503-V507 PolarHBondContact O-N 3.16Å
504A98.6Very high98.3Very high1 Ų17.5 Ų7.51%0.0084%0.037CC..Hα-helixtrans-57.4-49.217500000111.5L496 I497 W500 P501 S506 V507 Q508L496-A504 HydrophobicContact CB-CB 3.91Å; I497-A504 HydrophobicContact CB-CB 4.05Å; I497-A504 HydrophobicContact CD1-CB 3.85Å; W500-A504 PolarHBondContact O-N 3.09Å; P501-A504 PolarHBondContact O-N 2.69Å; A504-S506 VanDerWaalsContact C-N 3.3Å; A504-S506 PolarHBondContact O-N 3.04Å; A504-V507 WeakPolarHBondContact O-CB 3.46Å; A504-V507 PolarHBondContact O-N 3.34Å; A504-Q508 WeakPolarHBondContact O-CG 3.37Å; A504-Q508 PolarHBondContact O-N 3.4Å; A504-Q508 VanDerWaalsContact O-N 3.11Å
505L98.8Very high98.2Very high1 Ų17.5 Ų7.51%0.0054%0.037CC..Hα-helixtrans-64.1-34.4177-63.4-177.4000112.2L465 I497 P501 L503 Q508 Y509 D580 T584 Y589L465-L505 HydrophobicContact CD1-CB 3.67Å; L465-L505 HydrophobicContact CD1-CD1 3.58Å; L465-L505 HydrophobicContact CD1-CG 4.28Å; L465-L505 HydrophobicContact CD2-CB 3.88Å; L465-L505 HydrophobicContact CG-CB 4.47Å; I497-L505 HydrophobicContact CD1-CD2 4.38Å; P501-L505 WeakPolarHBondContact O-CG 3.46Å; P501-L505 PolarHBondContact O-N 3.01Å; L503-L505 PolarHBondContact O-N 2.78Å; L505-Q508 PolarHBondContact O-N 3.49Å; L505-Y509 VanDerWaalsContact O-CD2 3.25Å; L505-Y509 WeakPolarHBondContact O-CD2 3.46Å; L505-Y509 PolarHBondContact O-N 3Å; L505-D580 HydrophobicContact CD2-CB 3.87Å; L505-T584 HydrophobicContact CD1-CG2 4.22Å; L505-Y589 HydrophobicContact CD2-CD1 4.1Å; L505-Y589 HydrophobicContact CD2-CD2 3.89Å; L505-Y589 HydrophobicContact CD2-CE1 3.92Å; L505-Y589 HydrophobicContact CD2-CE2 3.69Å; L505-Y589 HydrophobicContact CD2-CG 4.08Å
506S98.4Very high97.9Very high0 Ų08.1 Ų8.10%04%0.04CC..Hα-helixtrans-62-46175-178.60000112G470 K502 L503 A504 Q508 Y509 D510G470-S506 PolarHBondContact O-OG 3.1Å; K502-S506 WeakPolarHBondContact O-CB 3.4Å; K502-S506 PolarHBondContact O-N 2.85Å; K502-S506 VanDerWaalsContact O-N 3.12Å; L503-S506 WeakPolarHBondContact O-CB 3.45Å; L503-S506 PolarHBondContact O-N 3.16Å; L503-S506 VanDerWaalsContact O-N 3.17Å; A504-S506 VanDerWaalsContact C-N 3.3Å; A504-S506 PolarHBondContact O-N 3.04Å; S506-Q508 VanDerWaalsContact C-N 3.27Å; S506-Q508 PolarHBondContact O-N 2.89Å; S506-Y509 PolarHBondContact O-N 2.86Å; S506-D510 PolarHBondContact O-N 3.37Å
507V98.5Very high97.7Very high0 Ų010.7 Ų10.70%05%0.052CC..Hα-helixtrans-56.2-44172.7173.40000110.9F472 L503 A504 Y509 D510 I511F472-V507 HydrophobicContact CB-CG2 4.15Å; F472-V507 HydrophobicContact CD1-CG2 3.69Å; F472-V507 HydrophobicContact CG-CG2 4.41Å; L503-V507 PolarHBondContact O-N 3.16Å; A504-V507 WeakPolarHBondContact O-CB 3.46Å; A504-V507 PolarHBondContact O-N 3.34Å; V507-Y509 PolarHBondContact O-N 3.49Å; V507-D510 PolarHBondContact O-N 3.31Å; V507-I511 HydrophobicContact CG1-CG1 4.25Å; V507-I511 VanDerWaalsContact O-CG1 3.31Å; V507-I511 WeakPolarHBondContact O-CG1 3.32Å; V507-I511 PolarHBondContact O-N 3.46Å
508Q98.4Very high97.5Very high0 Ų016.8 Ų16.80%08%0.081CC..Hα-helixtrans-65.9-38.6-178.9-66.6-70.271.500113Y486 A504 L505 S506 I511 A512 Q576 D580 Y589Y486-Q508 PolarHBondContact OH-NE2 3.08Å; Y486-Q508 PolarHBondContact OH-OE1 3.1Å; A504-Q508 WeakPolarHBondContact O-CG 3.37Å; A504-Q508 PolarHBondContact O-N 3.4Å; A504-Q508 VanDerWaalsContact O-N 3.11Å; L505-Q508 PolarHBondContact O-N 3.49Å; S506-Q508 VanDerWaalsContact C-N 3.27Å; S506-Q508 PolarHBondContact O-N 2.89Å; Q508-I511 PolarHBondContact O-N 3.32Å; Q508-A512 WeakPolarHBondContact O-CB 3.12Å; Q508-A512 PolarHBondContact O-N 3.04Å; Q508-Q576 VanDerWaalsContact NE2-CB 3.34Å; Q508-D580 WeakPolarHBondContact CG-OD2 3.46Å; Q508-Y589 HydrophobicContact CB-CE2 3.94Å; Q508-Y589 VanDerWaalsContact CB-OH 3.27Å; Q508-Y589 WeakPolarHBondContact CB-OH 3.49Å; Q508-Y589 WeakPolarHBondContact CG-OH 3.36Å
509Y98.3Very high97.3Very high8 Ų817.7 Ų17.73%0.0319%0.086CC..Hα-helixtrans-64.5-42.9173-85.4-70.7000112.1L459 P463 L465 V466 L505 S506 V507 A512 G513 Y589 D592 M593L459-Y509 HydrophobicContact CD1-CD1 4.38Å; L459-Y509 HydrophobicContact CD2-CD1 4.22Å; L459-Y509 HydrophobicContact CD2-CE1 4.29Å; P463-Y509 HydrophobicContact CB-CD1 3.85Å; P463-Y509 HydrophobicContact CB-CD2 4.36Å; P463-Y509 HydrophobicContact CB-CE1 3.83Å; P463-Y509 HydrophobicContact CB-CE2 4.34Å; P463-Y509 HydrophobicContact CB-CG 4.13Å; P463-Y509 HydrophobicContact CG-CD1 3.59Å; P463-Y509 HydrophobicContact CG-CE1 3.94Å; P463-Y509 HydrophobicContact CG-CG 4.06Å; L465-Y509 HydrophobicContact CB-CE2 4.34Å; L465-Y509 HydrophobicContact CD2-CD2 4.24Å; L465-Y509 HydrophobicContact CD2-CE2 4.47Å; V466-Y509 HydrophobicContact CG2-CD2 4.11Å; V466-Y509 HydrophobicContact CG2-CG 4.12Å; L505-Y509 VanDerWaalsContact O-CD2 3.25Å; L505-Y509 WeakPolarHBondContact O-CD2 3.46Å; L505-Y509 PolarHBondContact O-N 3Å; S506-Y509 PolarHBondContact O-N 2.86Å; V507-Y509 PolarHBondContact O-N 3.49Å; Y509-A512 PolarHBondContact O-N 3.08Å; Y509-G513 PolarHBondContact O-N 3.28Å; Y509-Y589 HydrophobicContact CD2-CD2 4.36Å; Y509-Y589 AromaticContact CE2-CD2 3.72Å; Y509-Y589 HydrophobicContact CE2-CD2 3.72Å; Y509-Y589 HydrophobicContact CE2-CE2 4.36Å; Y509-Y589 AromaticContact CZ-CD2 3.92Å; Y509-D592 HydrophobicContact CE1-CB 3.88Å; Y509-D592 WeakPolarHBondContact CE1-OD2 3.1Å; Y509-D592 PolarHBondContact OH-OD2 2.8Å; Y509-M593 HydrophobicContact CD1-CE 3.34Å; Y509-M593 HydrophobicContact CD2-CE 4.15Å; Y509-M593 HydrophobicContact CE1-CE 3.62Å; Y509-M593 HydrophobicContact CE2-CE 4.37Å; Y509-M593 HydrophobicContact CG-CE 3.64Å
510D96.6Very high97.2Very high2 Ų221.7 Ų21.71%0.01111%0.113CC..Hα-helixtrans-58.5-50.1174.9-90-28.9000110.6R471 S506 V507 A512 G513 T514 W552R471-D510 IonicContact CZ-OD1 3.43Å; R471-D510 VanDerWaalsContact CZ-OD1 3.29Å; R471-D510 IonicContact CZ-OD2 2.77Å; R471-D510 IonicContact NE-OD1 3.66Å; R471-D510 PolarHBondContact NE-OD1 2.9Å; R471-D510 IonicContact NE-OD2 3.77Å; R471-D510 PolarHBondContact NE-OD2 2.67Å; R471-D510 IonicContact NH2-OD1 3.7Å; R471-D510 PolarHBondContact NH2-OD1 3.43Å; R471-D510 IonicContact NH2-OD2 3.26Å; S506-D510 PolarHBondContact O-N 3.37Å; V507-D510 PolarHBondContact O-N 3.31Å; D510-A512 PolarHBondContact O-N 3.42Å; D510-G513 PolarHBondContact O-N 3.47Å; D510-T514 WeakPolarHBondContact O-CG2 3.24Å; D510-T514 PolarHBondContact O-N 2.63Å; D510-T514 VanDerWaalsContact O-N 3.13Å; D510-W552 PolarHBondContact OD2-NE1 3.47Å
511I98.2Very high97.1Very high0 Ų025.7 Ų25.70%014%0.138CC..Hα-helixtrans-62.5-46.4179.2-65.3-71.1000111.1Y486 V507 Q508 G513 T514 V515 V540 P541 I544 F573Y486-I511 HydrophobicContact CD2-CB 4.44Å; Y486-I511 HydrophobicContact CD2-CD1 3.74Å; Y486-I511 HydrophobicContact CD2-CG1 3.71Å; Y486-I511 HydrophobicContact CD2-CG2 4.07Å; Y486-I511 HydrophobicContact CE1-CG2 4.5Å; Y486-I511 HydrophobicContact CE2-CB 4.08Å; Y486-I511 HydrophobicContact CE2-CD1 4.22Å; Y486-I511 HydrophobicContact CE2-CG1 3.67Å; Y486-I511 HydrophobicContact CE2-CG2 3.79Å; Y486-I511 HydrophobicContact CG-CD1 4.45Å; V507-I511 HydrophobicContact CG1-CG1 4.25Å; V507-I511 VanDerWaalsContact O-CG1 3.31Å; V507-I511 WeakPolarHBondContact O-CG1 3.32Å; V507-I511 PolarHBondContact O-N 3.46Å; Q508-I511 PolarHBondContact O-N 3.32Å; I511-G513 VanDerWaalsContact C-N 3.25Å; I511-G513 PolarHBondContact O-N 2.78Å; I511-T514 WeakPolarHBondContact O-CA 3.28Å; I511-T514 PolarHBondContact O-N 3.26Å; I511-T514 PolarHBondContact O-OG1 3.24Å; I511-V515 PolarHBondContact O-N 3.12Å; I511-V515 VanDerWaalsContact O-N 3.08Å; I511-V540 HydrophobicContact CG2-CG1 3.9Å; I511-P541 HydrophobicContact CD1-CG 4.38Å; I511-I544 HydrophobicContact CD1-CG2 3.58Å; I511-F573 HydrophobicContact CG2-CD2 3.78Å; I511-F573 HydrophobicContact CG2-CE2 4Å
512A98.1Very high97Very high0 Ų029.9 Ų29.90%016%0.156CC..Hα-helixtrans-58.4-39.1178.200000112.1L459 Q508 Y509 D510 T514 V515 F573 M593 I596L459-A512 HydrophobicContact CD1-CB 3.68Å; Q508-A512 WeakPolarHBondContact O-CB 3.12Å; Q508-A512 PolarHBondContact O-N 3.04Å; Y509-A512 PolarHBondContact O-N 3.08Å; D510-A512 PolarHBondContact O-N 3.42Å; A512-T514 VanDerWaalsContact C-N 3.3Å; A512-T514 PolarHBondContact O-N 3.11Å; A512-V515 WeakPolarHBondContact O-CB 3.34Å; A512-V515 PolarHBondContact O-N 3.33Å; A512-F573 HydrophobicContact CB-CE2 3.96Å; A512-F573 HydrophobicContact CB-CZ 3.76Å; A512-M593 HydrophobicContact CB-CE 3.88Å; A512-M593 HydrophobicContact CB-SD 3.53Å; A512-M593 VanDerWaalsContact CB-SD 3.53Å; A512-I596 HydrophobicContact CB-CG1 4.38Å; A512-I596 HydrophobicContact CB-CG2 4.17Å
513G96.4Very high96.8Very high0 Ų028.3 Ų28.30%015%0.148CC..Hα-helixtrans-61.6-35.5172.700000113.7I448 G450 L459 Y509 D510 I511 V516 Q517I448-G513 WeakPolarHBondContact O-CA 3.47Å; G450-G513 VanDerWaalsContact CA-O 3.26Å; G450-G513 WeakPolarHBondContact CA-O 3.42Å; L459-G513 VanDerWaalsContact CD1-N 3.33Å; Y509-G513 PolarHBondContact O-N 3.28Å; D510-G513 PolarHBondContact O-N 3.47Å; I511-G513 VanDerWaalsContact C-N 3.25Å; I511-G513 PolarHBondContact O-N 2.78Å; G513-V516 WeakPolarHBondContact O-CG2 3.49Å; G513-Q517 WeakPolarHBondContact O-CG 3.26Å; G513-Q517 PolarHBondContact O-NE2 2.99Å; G513-Q517 VanDerWaalsContact O-NE2 3.08Å
514T96.2Very high96.6Very high4 Ų431 Ų313%0.02516%0.162CC..Hα-helixtrans-76.1-24.6176.866.90000113.8D510 I511 A512 V516 Q517 K535 P541 L555D510-T514 WeakPolarHBondContact O-CG2 3.24Å; D510-T514 PolarHBondContact O-N 2.63Å; D510-T514 VanDerWaalsContact O-N 3.13Å; I511-T514 WeakPolarHBondContact O-CA 3.28Å; I511-T514 PolarHBondContact O-N 3.26Å; I511-T514 PolarHBondContact O-OG1 3.24Å; A512-T514 VanDerWaalsContact C-N 3.3Å; A512-T514 PolarHBondContact O-N 3.11Å; T514-V516 VanDerWaalsContact C-N 3.32Å; T514-V516 PolarHBondContact O-N 3.35Å; T514-Q517 WeakPolarHBondContact O-CB 3.17Å; T514-Q517 PolarHBondContact O-N 2.99Å; T514-K535 WeakPolarHBondContact O-CE 3.31Å; T514-K535 PolarHBondContact O-NZ 3.21Å; T514-P541 WeakPolarHBondContact OG1-CD 3.36Å; T514-P541 WeakPolarHBondContact OG1-CG 3.41Å; T514-L555 HydrophobicContact CG2-CD1 3.6Å; T514-L555 HydrophobicContact CG2-CD2 3.72Å; T514-L555 HydrophobicContact CG2-CG 4.31Å
515V97.1Very high96.5Very high0 Ų030.9 Ų30.90%016%0.161CC..Hα-helixtrans-57.5-46.4-180167.20000111I511 A512 Q517 K535 N538 V540 I596 V600I511-V515 PolarHBondContact O-N 3.12Å; I511-V515 VanDerWaalsContact O-N 3.08Å; A512-V515 WeakPolarHBondContact O-CB 3.34Å; A512-V515 PolarHBondContact O-N 3.33Å; V515-Q517 VanDerWaalsContact C-N 3.27Å; V515-Q517 PolarHBondContact O-N 3.24Å; V515-K535 PolarHBondContact O-NZ 3.18Å; V515-N538 WeakPolarHBondContact O-CA 3.48Å; V515-N538 PolarHBondContact O-N 2.86Å; V515-V540 HydrophobicContact CG2-CB 4.36Å; V515-V540 HydrophobicContact CG2-CG2 3.59Å; V515-I596 HydrophobicContact CB-CG2 3.87Å; V515-I596 HydrophobicContact CG1-CG2 3.79Å; V515-I596 HydrophobicContact CG2-CG2 4.09Å; V515-V600 HydrophobicContact CG1-CG1 3.45Å; V515-V600 VanDerWaalsContact CG1-CG1 3.45Å; V515-V600 HydrophobicContact CG2-CG1 4.21Å
516V93.6Very high96.3Very high13 Ų1331 Ų318%0.07916%0.162CC..THydrogen-bonded Turntrans-79.1-9.3-176.2-630000113.8S449 V452 G513 T514 I596S449-V516 VanDerWaalsContact O-CG2 3.27Å; S449-V516 WeakPolarHBondContact O-CG2 3.2Å; V452-V516 HydrophobicContact CB-CB 4.36Å; V452-V516 HydrophobicContact CB-CG2 4.13Å; V452-V516 HydrophobicContact CG2-CB 3.91Å; V452-V516 HydrophobicContact CG2-CG2 3.99Å; G513-V516 WeakPolarHBondContact O-CG2 3.49Å; T514-V516 VanDerWaalsContact C-N 3.32Å; T514-V516 PolarHBondContact O-N 3.35Å; V516-I596 HydrophobicContact CG1-CD1 3.64Å
517Q93Very high95.9Very high55 Ų5533.4 Ų33.426%0.25717%0.174SC..  trans-79.9156.2175-64.1174.135.500111.9G450 G513 T514 V515 K535G450-Q517 WeakPolarHBondContact O-CG 3.45Å; G513-Q517 WeakPolarHBondContact O-CG 3.26Å; G513-Q517 PolarHBondContact O-NE2 2.99Å; G513-Q517 VanDerWaalsContact O-NE2 3.08Å; T514-Q517 WeakPolarHBondContact O-CB 3.17Å; T514-Q517 PolarHBondContact O-N 2.99Å; V515-Q517 VanDerWaalsContact C-N 3.27Å; V515-Q517 PolarHBondContact O-N 3.24Å; Q517-K535 PolarHBondContact O-NZ 2.85Å
518Q94.4Very high95.6Very high133 Ų13337 Ų3762%0.62119%0.193SC*.  trans-135.6148169.665.4-177.95.200110.5K535 K537Q518-K535 CarbonylContact C-O 3.5Å; Q518-K535 WeakPolarHBondContact CA-O 3.17Å; Q518-K537 HydrophobicContact CB-CB 4.17Å
519D95.9Very high95.4Very high57 Ų5738.3 Ų38.331%0.30521%0.206SC..EExtended strand (participates in β ladder)trans-129.3103.2167.1-177.6-7.2000107.7T521 P533 V534 K535D519-T521 PolarHBondContact O-N 2.82Å; D519-T521 WeakPolarHBondContact OD1-CB 3.42Å; D519-T521 PolarHBondContact OD1-N 3.27Å; D519-T521 PolarHBondContact OD1-OG1 3.05Å; D519-P533 WeakPolarHBondContact O-CB 3Å; D519-V534 HydrophobicContact CB-CB 4Å; D519-V534 HydrophobicContact CB-CG1 4.27Å; D519-V534 PolarHBondContact O-N 3.24Å; D519-K535 HydrophobicContact CB-CB 3.95Å; D519-K535 PolarHBondContact N-O 2.79Å; D519-K535 PolarHBondContact O-N 3.47Å
520P96.3Very high95.2Very high95 Ų9546.4 Ų46.462%0.61724%0.237SC*.EExtended strand (participates in β ladder)trans-77.22.6-177.934.2-36.3000113E522P520-E522 PolarHBondContact O-N 2.77Å
521T96.7Very high95.2Very high86 Ų8653.2 Ų53.253%0.52826%0.264SS..EExtended strand (participates in β ladder)trans-61.7121.4177.3-54.30000109.6D519 P533 V534D519-T521 PolarHBondContact O-N 2.82Å; D519-T521 WeakPolarHBondContact OD1-CB 3.42Å; D519-T521 PolarHBondContact OD1-N 3.27Å; D519-T521 PolarHBondContact OD1-OG1 3.05Å; T521-P533 CarbonylContact O-C 3.6Å; T521-V534 VanDerWaalsContact O-CG2 3.3Å; T521-V534 WeakPolarHBondContact O-CG2 3.49Å; T521-V534 PolarHBondContact O-N 3.05Å
522E96Very high95.1Very high106 Ų10654.3 Ų54.350%0.49527%0.271SS..EExtended strand (participates in β ladder)trans-72.8132179.6-71-72.6126.600111.2P520 Y531 S532 P533P520-E522 PolarHBondContact O-N 2.77Å; E522-Y531 HydrophobicContact CB-CD1 4.28Å; E522-Y531 VanDerWaalsContact OE2-CB 3.29Å; E522-Y531 WeakPolarHBondContact OE2-CB 3.39Å; E522-S532 WeakPolarHBondContact CA-O 3.29Å; E522-S532 PolarHBondContact OE2-N 3.34Å; E522-P533 WeakPolarHBondContact OE1-CD 3.25Å
523R94.6Very high95Very high33 Ų3356.3 Ų56.313%0.12528%0.284CS..EExtended strand (participates in β ladder)trans-130.4147.7175.364.5173.3-179.7172.59.8111.9H525 Y531 S532 V534 N556 Y558R523-H525 PolarHBondContact NE-CE1 2.8Å; R523-Y531 VanDerWaalsContact O-CA 3.27Å; R523-Y531 WeakPolarHBondContact O-CA 3.34Å; R523-S532 WeakPolarHBondContact CG-O 3.36Å; R523-S532 PolarHBondContact N-O 2.85Å; R523-S532 PolarHBondContact O-N 3.37Å; R523-S532 VanDerWaalsContact O-N 3.14Å; R523-V534 HydrophobicContact CB-CG2 4.2Å; R523-V534 HydrophobicContact CG-CG2 4.03Å; R523-N556 PolarHBondContact NH1-O 3.28Å; R523-Y558 PolarHBondContact NH1-O 3.38Å; R523-Y558 PolarHBondContact NH2-O 3.2Å; R523-Y558 VanDerWaalsContact NH2-O 3.09Å
524L95.5Very high95Very high56 Ų5657.4 Ų57.429%0.29329%0.291SS..EExtended strand (participates in β ladder)trans-78.7122175.9179.569.2000110.7G529 Y531L524-G529 VanDerWaalsContact CD1-C 3.45Å; L524-G529 VanDerWaalsContact CD1-O 3.29Å; L524-G529 WeakPolarHBondContact CD1-O 3.36Å; L524-Y531 HydrophobicContact CB-CD1 4.36Å; L524-Y531 HydrophobicContact CB-CE1 3.89Å; L524-Y531 HydrophobicContact CB-CE2 4.24Å; L524-Y531 HydrophobicContact CD1-CD2 4.04Å; L524-Y531 HydrophobicContact CD1-CE2 3.69Å
525H94.8Very high95Very high0 Ų057.5 Ų57.50%029%0.291CS..  trans-87.6131.1171.1-65.7-83.7000111.2R523 G529 R530 L559 H561 D562R523-H525 PolarHBondContact NE-CE1 2.8Å; H525-G529 WeakPolarHBondContact O-CA 3.19Å; H525-G529 PolarHBondContact O-N 2.73Å; H525-R530 PolarHBondContact N-O 2.91Å; H525-L559 WeakPolarHBondContact CA-O 3.37Å; H525-H561 PolarHBondContact CE1-O 3.13Å; H525-H561 PolarHBondContact ND1-O 2.96Å; H525-D562 VanDerWaalsContact CE1-CA 3.43Å; H525-D562 WeakPolarHBondContact CE1-CA 3.29Å; H525-D562 WeakPolarHBondContact ND1-CA 3.47Å; H525-D562 PolarHBondContact ND1-N 3.02Å
526L94.6Very high95Very high2 Ų259.9 Ų59.91%0.0131%0.305CS..THydrogen-bonded Turntrans-76.1-29.3-166.5-56.6-177.1000113.3L62 R65 Y66 W69 L559 I560L62-L526 HydrophobicContact CD1-CB 3.64Å; L62-L526 WeakPolarHBondContact CD1-O 3.34Å; R65-L526 HydrophobicContact CB-CD2 4.03Å; R65-L526 PolarHBondContact NE-O 3.37Å; R65-L526 PolarHBondContact NH2-O 3.46Å; R65-L526 VanDerWaalsContact NH2-O 3.1Å; Y66-L526 HydrophobicContact CD2-CD1 3.8Å; W69-L526 HydrophobicContact CB-CD1 4.2Å; W69-L526 HydrophobicContact CB-CD2 4.06Å; W69-L526 HydrophobicContact CD2-CD1 4.14Å; W69-L526 HydrophobicContact CE3-CD1 4.27Å; W69-L526 HydrophobicContact CG-CD1 4.1Å; W69-L526 HydrophobicContact CG-CD2 4.4Å; L526-L559 HydrophobicContact CD1-CD1 3.33Å; L526-L559 HydrophobicContact CD2-CD1 4.13Å; L526-L559 HydrophobicContact CG-CD1 3.41Å; L526-L559 VanDerWaalsContact CG-CD1 3.41Å; L526-L559 PolarHBondContact N-O 2.9Å; L526-I560 HydrophobicContact CB-CD1 4.47Å; L526-I560 HydrophobicContact CD1-CD1 4.03Å; L526-I560 PolarHBondContact N-O 2.96Å
527M91.8Very high95.1Very high51 Ų5164 Ų6425%0.25132%0.322SS..THydrogen-bonded Turntrans-67.6-54.7-178.6-17659.879.700111.6L62 R65 I560 H561L62-M527 HydrophobicContact CB-SD 4.46Å; L62-M527 HydrophobicContact CD2-CE 3.86Å; L62-M527 HydrophobicContact CD2-SD 4.06Å; R65-M527 PolarHBondContact NH2-O 2.76Å; M527-I560 HydrophobicContact CB-CG2 4.27Å; M527-I560 WeakPolarHBondContact CB-O 3.35Å; M527-I560 HydrophobicContact CE-CG2 4.24Å; M527-I560 PolarHBondContact N-O 3.27Å; M527-H561 WeakPolarHBondContact CE-NE2 3.2Å
528N91Very high95.2Very high76 Ų7663.7 Ų63.741%0.40632%0.322SS..THydrogen-bonded Turntrans-98.6-15.7-1756516.1000113.9R530N528-R530 VanDerWaalsContact C-N 3.33Å; N528-R530 HydrophobicContact CB-CG 4.39Å; N528-R530 WeakPolarHBondContact OD1-CB 3.29Å; N528-R530 PolarHBondContact OD1-N 3.47Å
529G93.6Very high95.4Very high27 Ų2757.7 Ų57.728%0.27830%0.295SS..  trans73.418.6-176.700000114.9L524 H525L524-G529 VanDerWaalsContact CD1-C 3.45Å; L524-G529 VanDerWaalsContact CD1-O 3.29Å; L524-G529 WeakPolarHBondContact CD1-O 3.36Å; H525-G529 WeakPolarHBondContact O-CA 3.19Å; H525-G529 PolarHBondContact O-N 2.73Å
530R94.6Very high95.5Very high178 Ų17855 Ų5567%0.67228%0.28SS*.  trans-92.2154.1177.2-63.4-176.2178.3177.4-0.1111.2H525 N528H525-R530 PolarHBondContact N-O 2.91Å; N528-R530 VanDerWaalsContact C-N 3.33Å; N528-R530 HydrophobicContact CB-CG 4.39Å; N528-R530 WeakPolarHBondContact OD1-CB 3.29Å; N528-R530 PolarHBondContact OD1-N 3.47Å
531Y96.3Very high95.6Very high146 Ų14650.5 Ų50.557%0.57325%0.251SS*.EExtended strand (participates in β ladder)trans-95.3136.8169.5-75.2-99.7000109.6E522 R523 L524E522-Y531 HydrophobicContact CB-CD1 4.28Å; E522-Y531 VanDerWaalsContact OE2-CB 3.29Å; E522-Y531 WeakPolarHBondContact OE2-CB 3.39Å; R523-Y531 VanDerWaalsContact O-CA 3.27Å; R523-Y531 WeakPolarHBondContact O-CA 3.34Å; L524-Y531 HydrophobicContact CB-CD1 4.36Å; L524-Y531 HydrophobicContact CB-CE1 3.89Å; L524-Y531 HydrophobicContact CB-CE2 4.24Å; L524-Y531 HydrophobicContact CD1-CD2 4.04Å; L524-Y531 HydrophobicContact CD1-CE2 3.69Å
532S95.8Very high95.7Very high23 Ų2346.6 Ų46.616%0.16123%0.227CC..EExtended strand (participates in β ladder)trans-151.1162.4176-53.60000109.5E522 R523E522-S532 WeakPolarHBondContact CA-O 3.29Å; E522-S532 PolarHBondContact OE2-N 3.34Å; R523-S532 WeakPolarHBondContact CG-O 3.36Å; R523-S532 PolarHBondContact N-O 2.85Å; R523-S532 PolarHBondContact O-N 3.37Å; R523-S532 VanDerWaalsContact O-N 3.14Å
533P96.8Very high95.8Very high41 Ų4141.6 Ų41.627%0.26620%0.203SC..EExtended strand (participates in β ladder)trans-56.2146.5176.1-28.137.1000112.7D519 T521 E522 K535D519-P533 WeakPolarHBondContact O-CB 3Å; T521-P533 CarbonylContact O-C 3.6Å; E522-P533 WeakPolarHBondContact OE1-CD 3.25Å; P533-K535 VanDerWaalsContact C-N 3.29Å; P533-K535 PolarHBondContact O-N 3.23Å
534V96Very high95.9Very high23 Ų2340 Ų4014%0.13920%0.197CC..EExtended strand (participates in β ladder)trans-60.7-40.8174.4168.60000111.3D519 T521 R523 N556D519-V534 HydrophobicContact CB-CB 4Å; D519-V534 HydrophobicContact CB-CG1 4.27Å; D519-V534 PolarHBondContact O-N 3.24Å; T521-V534 VanDerWaalsContact O-CG2 3.3Å; T521-V534 WeakPolarHBondContact O-CG2 3.49Å; T521-V534 PolarHBondContact O-N 3.05Å; R523-V534 HydrophobicContact CB-CG2 4.2Å; R523-V534 HydrophobicContact CG-CG2 4.03Å; V534-N556 PolarHBondContact O-ND2 3.12Å
535K96.7Very high96Very high6 Ų637.3 Ų37.33%0.02618%0.183CC..EExtended strand (participates in β ladder)trans-145.5119.7-177.2176.462.4173.7630111.3T514 V515 Q517 Q518 D519 P533 V539 P541 L555T514-K535 WeakPolarHBondContact O-CE 3.31Å; T514-K535 PolarHBondContact O-NZ 3.21Å; V515-K535 PolarHBondContact O-NZ 3.18Å; Q517-K535 PolarHBondContact O-NZ 2.85Å; Q518-K535 CarbonylContact C-O 3.5Å; Q518-K535 WeakPolarHBondContact CA-O 3.17Å; D519-K535 HydrophobicContact CB-CB 3.95Å; D519-K535 PolarHBondContact N-O 2.79Å; D519-K535 PolarHBondContact O-N 3.47Å; P533-K535 VanDerWaalsContact C-N 3.29Å; P533-K535 PolarHBondContact O-N 3.23Å; K535-V539 WeakPolarHBondContact CE-O 3.5Å; K535-V539 PolarHBondContact NZ-O 2.63Å; K535-P541 HydrophobicContact CD-CB 4.32Å; K535-L555 HydrophobicContact CG-CD1 4.44Å
536T96.3Very high96Very high50 Ų5037.8 Ų37.831%0.30719%0.186SC..  trans-88.3140174.8-59.50000111V539 A564T536-V539 HydrophobicContact CG2-CG2 4.09Å; T536-V539 PolarHBondContact O-N 2.88Å; T536-A564 WeakPolarHBondContact OG1-CB 3.5Å
537K95.7Very high96.1Very high101 Ų10137.8 Ų37.844%0.43919%0.186SC..THydrogen-bonded Turntrans-62.7145176.9-168.4173.1-178.4-179.40111.2Q518 V539Q518-K537 HydrophobicContact CB-CB 4.17Å; K537-V539 PolarHBondContact O-N 3.25Å
538N96.8Very high96.2Very high48 Ų4836.5 Ų36.526%0.25718%0.18SC..THydrogen-bonded Turntrans63.319.2-179.7-58.1-14.6000114.4V515 A599 S603V515-N538 WeakPolarHBondContact O-CA 3.48Å; V515-N538 PolarHBondContact O-N 2.86Å; N538-A599 HydrophobicContact CB-CB 4.39Å; N538-S603 PolarHBondContact O-OG 3.26Å
539V97.2Very high96.4Very high6 Ų634.1 Ų34.14%0.03617%0.168CC..SBendtrans-118.9131.3173.5-175.40000108.9K535 T536 K537K535-V539 WeakPolarHBondContact CE-O 3.5Å; K535-V539 PolarHBondContact NZ-O 2.63Å; T536-V539 HydrophobicContact CG2-CG2 4.09Å; T536-V539 PolarHBondContact O-N 2.88Å; K537-V539 PolarHBondContact O-N 3.25Å
540V98.4Very high96.4Very high1 Ų132.9 Ų32.91%0.00615%0.154CC..  trans-62.3129.1173.2173.20000109Y486 I511 V515 L569 N570 F573 V600Y486-V540 HydrophobicContact CD1-CG1 3.43Å; Y486-V540 VanDerWaalsContact CD1-CG1 3.43Å; Y486-V540 HydrophobicContact CE1-CG1 3.86Å; Y486-V540 HydrophobicContact CG-CG1 3.9Å; I511-V540 HydrophobicContact CG2-CG1 3.9Å; V515-V540 HydrophobicContact CG2-CB 4.36Å; V515-V540 HydrophobicContact CG2-CG2 3.59Å; V540-L569 HydrophobicContact CB-CB 4.22Å; V540-L569 HydrophobicContact CG1-CB 4.39Å; V540-N570 VanDerWaalsContact CG2-OD1 3.31Å; V540-N570 WeakPolarHBondContact CG2-OD1 3.5Å; V540-N570 PolarHBondContact N-OD1 2.84Å; V540-F573 HydrophobicContact CG2-CB 3.56Å; V540-F573 HydrophobicContact CG2-CD1 4.45Å; V540-F573 HydrophobicContact CG2-CD2 4.17Å; V540-F573 HydrophobicContact CG2-CG 3.82Å; V540-V600 HydrophobicContact CG2-CG1 4.16Å
541P98.1Very high96.5Very high1 Ų124.4 Ų24.41%0.00612%0.123CC..  trans-65.2150.5174.631.7-36.7000110.3I511 T514 K535 D543 L555 N556I511-P541 HydrophobicContact CD1-CG 4.38Å; T514-P541 WeakPolarHBondContact OG1-CD 3.36Å; T514-P541 WeakPolarHBondContact OG1-CG 3.41Å; K535-P541 HydrophobicContact CD-CB 4.32Å; P541-D543 VanDerWaalsContact C-N 3.32Å; P541-L555 HydrophobicContact CB-CB 4.4Å; P541-N556 VanDerWaalsContact CA-OD1 3.24Å; P541-N556 WeakPolarHBondContact CA-OD1 3.18Å; P541-N556 WeakPolarHBondContact CB-OD1 3.49Å
542H98.4Very high96.4Very high4 Ų418 Ų182%0.01910%0.097CC..SBendtrans-61.1-44.7170.9171.7-89.9000110.8T485 Y486 D487 N556 Y558 T563 W566 L569T485-H542 CarbonylContact C-O 3.56Å; T485-H542 VanDerWaalsContact CA-O 3.25Å; T485-H542 WeakPolarHBondContact CA-O 3.48Å; T485-H542 WeakPolarHBondContact CG2-CE1 3.47Å; T485-H542 WeakPolarHBondContact CG2-NE2 3.17Å; Y486-H542 PolarHBondContact N-O 2.74Å; D487-H542 IonicContact OD1-CD2 2.73Å; D487-H542 PolarHBondContact OD1-CD2 3.24Å; D487-H542 IonicContact OD1-NE2 3.75Å; D487-H542 PolarHBondContact OD1-NE2 3.34Å; H542-N556 PolarHBondContact N-OD1 3.36Å; H542-Y558 VanDerWaalsContact CE1-CB 3.47Å; H542-Y558 WeakPolarHBondContact CE1-CB 3.32Å; H542-Y558 AromaticContact CE1-CD2 3.71Å; H542-Y558 AromaticContact CE1-CG 3.61Å; H542-Y558 WeakPolarHBondContact ND1-CB 3.49Å; H542-Y558 AromaticContact ND1-CG 3.77Å; H542-Y558 AromaticContact NE2-CD2 3.98Å; H542-Y558 AromaticContact NE2-CG 3.95Å; H542-T563 HydrophobicContact CB-CG2 3.84Å; H542-W566 AromaticContact CD2-CH2 3.93Å; H542-W566 AromaticContact CD2-CZ3 3.72Å; H542-L569 HydrophobicContact CB-CD1 4.3Å
543D98.6Very high96.3Very high0 Ų020.3 Ų20.30%011%0.106CC..  trans-149.3162.4-179.464.981.4000110.6M482 Y483 P541 G545 N556 A557 Y558M482-D543 HydrophobicContact CB-CB 3.81Å; M482-D543 HydrophobicContact CG-CB 4.45Å; Y483-D543 WeakPolarHBondContact O-CB 3.46Å; P541-D543 VanDerWaalsContact C-N 3.32Å; D543-G545 VanDerWaalsContact C-N 3.34Å; D543-G545 WeakPolarHBondContact OD1-CA 3.48Å; D543-G545 PolarHBondContact OD1-N 2.82Å; D543-N556 PolarHBondContact O-N 2.99Å; D543-A557 WeakPolarHBondContact OD1-CB 3.44Å; D543-A557 PolarHBondContact OD1-N 3.02Å; D543-A557 PolarHBondContact OD2-N 3.08Å; D543-Y558 WeakPolarHBondContact OD2-CB 3.34Å; D543-Y558 PolarHBondContact OD2-N 2.99Å
544I97.4Very high96.2Very high0 Ų023.4 Ų23.40%011%0.112CC..SBendtrans-92.912.2178.963.9161000113.1A473 Y483 N484 I511 P551 W552 L555A473-I544 HydrophobicContact CB-CD1 3.66Å; Y483-I544 VanDerWaalsContact O-CG1 3.26Å; Y483-I544 WeakPolarHBondContact O-CG1 3.39Å; Y483-I544 PolarHBondContact O-N 3.37Å; N484-I544 HydrophobicContact CB-CD1 4.29Å; N484-I544 HydrophobicContact CB-CG1 4.09Å; N484-I544 WeakPolarHBondContact ND2-CD1 3.44Å; I511-I544 HydrophobicContact CD1-CG2 3.58Å; I544-P551 CarbonylContact O-C 3.59Å; I544-P551 WeakPolarHBondContact O-CA 3.49Å; I544-W552 VanDerWaalsContact CD1-CD1 3.45Å; I544-W552 HydrophobicContact CD1-CD2 4.38Å; I544-W552 HydrophobicContact CD1-CG 4.12Å; I544-W552 PolarHBondContact O-N 2.76Å; I544-L555 HydrophobicContact CB-CD2 4.2Å; I544-L555 HydrophobicContact CG2-CD2 4.39Å
545G96.7Very high96.2Very high0 Ų023 Ų230%011%0.109CC..  trans122.1179.8170.600000116.1Y483 D543 R554Y483-G545 PolarHBondContact N-O 3.13Å; D543-G545 VanDerWaalsContact C-N 3.34Å; D543-G545 WeakPolarHBondContact OD1-CA 3.48Å; D543-G545 PolarHBondContact OD1-N 2.82Å; G545-R554 WeakPolarHBondContact CA-O 3.4Å
546D95.7Very high96.2Very high9 Ų923 Ų235%0.04811%0.109CC..  trans-103.6138.7-177.9-174.3-41.5000110.5R481 D548 D549 A557R481-D546 IonicContact CZ-OD1 2.73Å; R481-D546 IonicContact NH1-OD1 3.68Å; R481-D546 IonicContact NH2-OD1 3.35Å; R481-D546 PolarHBondContact NH2-OD1 3.39Å; R481-D546 IonicContact NH2-OD2 3.47Å; R481-D546 PolarHBondContact NH2-OD2 3.42Å; D546-D548 PolarHBondContact O-N 2.89Å; D546-D548 PolarHBondContact OD1-N 3.23Å; D546-D549 HydrophobicContact CB-CB 4.5Å; D546-D549 PolarHBondContact O-N 2.8Å; D546-A557 HydrophobicContact CB-CB 3.79Å
547P95.9Very high96.2Very high2 Ų221.4 Ų21.41%0.01310%0.101CC..THydrogen-bonded Turntrans-58-23.4174.423.1-34.3000115.6M124 G365 L475 R481 Y483 D549M124-P547 HydrophobicContact SD-CB 4.29Å; M124-P547 HydrophobicContact SD-CG 4.16Å; G365-P547 PolarHBondContact N-O 3.33Å; L475-P547 HydrophobicContact CD2-CG 4.27Å; R481-P547 HydrophobicContact CB-CG 4.1Å; R481-P547 WeakPolarHBondContact O-CD 3.5Å; Y483-P547 HydrophobicContact CE2-CB 3.82Å; Y483-P547 HydrophobicContact CE2-CG 4.35Å; P547-D549 VanDerWaalsContact C-N 3.3Å
548D94.1Very high96.3Very high24 Ų2416.8 Ų16.813%0.1288%0.081CC..THydrogen-bonded Turntrans-83-3.2174.1-84.9-30.5000113.7K79 A80 G365 S366 R481 D546K79-D548 HydrophobicContact CB-CB 4.4Å; K79-D548 HydrophobicContact CD-CB 4.43Å; K79-D548 PolarHBondContact NZ-O 3.46Å; A80-D548 WeakPolarHBondContact CB-OD2 3.15Å; A80-D548 PolarHBondContact N-OD2 2.7Å; G365-D548 CarbonylContact C-O 3.13Å; G365-D548 VanDerWaalsContact C-O 3.3Å; S366-D548 PolarHBondContact N-O 2.94Å; R481-D548 IonicContact CZ-OD2 3.68Å; R481-D548 IonicContact NH1-OD2 3.35Å; R481-D548 PolarHBondContact NH1-OD2 3.44Å; R481-D548 IonicContact NH2-OD2 2.79Å; D546-D548 PolarHBondContact O-N 2.89Å; D546-D548 PolarHBondContact OD1-N 3.23Å
549D94.7Very high96.2Very high27 Ų2715.8 Ų15.814%0.1448%0.075CC..SBendtrans-113.3-136.6173.9-85.5-48.4000109.7K79 F364 S366 D546 P547 R554K79-D549 IonicContact NZ-OD1 2.91Å; K79-D549 PolarHBondContact NZ-OD1 3.5Å; F364-D549 WeakPolarHBondContact CB-O 3.4Å; S366-D549 WeakPolarHBondContact CB-O 3.47Å; S366-D549 PolarHBondContact N-O 3.39Å; S366-D549 VanDerWaalsContact N-O 3.16Å; S366-D549 PolarHBondContact OG-O 3.35Å; D546-D549 HydrophobicContact CB-CB 4.5Å; D546-D549 PolarHBondContact O-N 2.8Å; P547-D549 VanDerWaalsContact C-N 3.3Å; D549-R554 IonicContact OD1-NH1 2.87Å; D549-R554 PolarHBondContact OD1-NH1 2.88Å
550E95.4Very high96Very high0 Ų015.8 Ų15.80%08%0.075CC..  trans-130.191.6179.5-173.464.8-126.500108.4S366 R369 H371 Q553 R554S366-E550 PolarHBondContact OG-OE2 2.86Å; R369-E550 PolarHBondContact N-OE2 2.96Å; H371-E550 IonicContact CD2-OE1 3.22Å; H371-E550 IonicContact CE1-OE1 3.24Å; H371-E550 PolarHBondContact CE1-OE1 2.64Å; H371-E550 IonicContact NE2-OE1 3.91Å; H371-E550 PolarHBondContact NE2-OE1 2.79Å; E550-Q553 HydrophobicContact CB-CB 4.44Å; E550-Q553 HydrophobicContact CG-CB 4.01Å; E550-Q553 HydrophobicContact CG-CG 4.15Å; E550-Q553 PolarHBondContact O-N 2.91Å; E550-R554 PolarHBondContact O-N 3.17Å
551P95.5Very high95.8Very high1 Ų116.2 Ų16.21%0.0068%0.077CC..THydrogen-bonded Turntrans-53.5154.4177.9-27.236.2000112.7F364 Y483 I544 Q553F364-P551 HydrophobicContact CD1-CG 3.8Å; F364-P551 HydrophobicContact CD2-CG 4.34Å; F364-P551 HydrophobicContact CE1-CG 3.76Å; F364-P551 HydrophobicContact CE2-CG 4.31Å; F364-P551 VanDerWaalsContact CG-CD 3.48Å; F364-P551 HydrophobicContact CG-CG 4.09Å; F364-P551 HydrophobicContact CZ-CB 4.44Å; F364-P551 HydrophobicContact CZ-CG 4.03Å; Y483-P551 HydrophobicContact CD2-CB 3.9Å; Y483-P551 HydrophobicContact CD2-CG 3.56Å; Y483-P551 HydrophobicContact CE2-CB 4.33Å; Y483-P551 HydrophobicContact CE2-CG 3.63Å; I544-P551 CarbonylContact O-C 3.59Å; I544-P551 WeakPolarHBondContact O-CA 3.49Å; P551-Q553 PolarHBondContact O-N 3.28Å
552W94.8Very high95.7Very high10 Ų1017.2 Ų17.24%0.0388%0.083CC..THydrogen-bonded Turntrans64.4-20.7-169.9-53.9-78000116.6F364 V438 T440 R471 A473 D510 I544F364-W552 HydrophobicContact CE2-CE3 4.49Å; F364-W552 AromaticContact CE2-CZ3 3.87Å; F364-W552 HydrophobicContact CE2-CZ3 3.87Å; F364-W552 HydrophobicContact CZ-CH2 4.44Å; F364-W552 AromaticContact CZ-CZ3 3.91Å; F364-W552 HydrophobicContact CZ-CZ3 3.91Å; V438-W552 HydrophobicContact CG2-CH2 3.98Å; V438-W552 HydrophobicContact CG2-CZ2 4.45Å; T440-W552 HydrophobicContact CG2-CH2 4.31Å; R471-W552 HydrophobicContact CB-CH2 4.23Å; R471-W552 HydrophobicContact CB-CZ2 3.68Å; R471-W552 VanDerWaalsContact NH1-CB 3.28Å; R471-W552 VanDerWaalsContact NH1-CG 3.29Å; R471-W552 VanDerWaalsContact NH2-CB 3.25Å; A473-W552 HydrophobicContact CB-CZ2 3.92Å; D510-W552 PolarHBondContact OD2-NE1 3.47Å; I544-W552 VanDerWaalsContact CD1-CD1 3.45Å; I544-W552 HydrophobicContact CD1-CD2 4.38Å; I544-W552 HydrophobicContact CD1-CG 4.12Å; I544-W552 PolarHBondContact O-N 2.76Å
553Q93.1Very high95.5Very high72 Ų7217.1 Ų17.134%0.3368%0.082SC..THydrogen-bonded Turntrans-99.7-44.5176-69.3174.162.100111.6E550 P551E550-Q553 HydrophobicContact CB-CB 4.44Å; E550-Q553 HydrophobicContact CG-CB 4.01Å; E550-Q553 HydrophobicContact CG-CG 4.15Å; E550-Q553 PolarHBondContact O-N 2.91Å; P551-Q553 PolarHBondContact O-N 3.28Å
554R95.1Very high95.4Very high107 Ų10717.6 Ų17.640%0.4049%0.086SC..SBendtrans-101.881.8178.1-65.6-179.3-177-171.71.5109.4E368 G545 D549 E550E368-R554 VanDerWaalsContact CD-NH2 3.27Å; E368-R554 IonicContact OE1-CZ 2.74Å; E368-R554 IonicContact OE1-NH1 3.21Å; E368-R554 IonicContact OE1-NH2 3.48Å; E368-R554 PolarHBondContact OE1-NH2 3.49Å; E368-R554 IonicContact OE2-CZ 2.69Å; E368-R554 IonicContact OE2-NH2 3.88Å; E368-R554 PolarHBondContact OE2-NH2 3.08Å; G545-R554 WeakPolarHBondContact CA-O 3.4Å; D549-R554 IonicContact OD1-NH1 2.87Å; D549-R554 PolarHBondContact OD1-NH1 2.88Å; E550-R554 PolarHBondContact O-N 3.17Å
555L96.2Very high95.2Very high13 Ų1320.2 Ų20.27%0.06810%0.1CC..  trans-71.2164.9-179-51.3178000111.8T514 K535 P541 I544T514-L555 HydrophobicContact CG2-CD1 3.6Å; T514-L555 HydrophobicContact CG2-CD2 3.72Å; T514-L555 HydrophobicContact CG2-CG 4.31Å; K535-L555 HydrophobicContact CG-CD1 4.44Å; P541-L555 HydrophobicContact CB-CB 4.4Å; I544-L555 HydrophobicContact CB-CD2 4.2Å; I544-L555 HydrophobicContact CG2-CD2 4.39Å
556N96.9Very high95.2Very high7 Ų720.3 Ų20.34%0.03710%0.101CC..  trans5359.7176.8-67.3-29.5000111.8R523 V534 P541 H542 D543 Y558R523-N556 PolarHBondContact NH1-O 3.28Å; V534-N556 PolarHBondContact O-ND2 3.12Å; P541-N556 VanDerWaalsContact CA-OD1 3.24Å; P541-N556 WeakPolarHBondContact CA-OD1 3.18Å; P541-N556 WeakPolarHBondContact CB-OD1 3.49Å; H542-N556 PolarHBondContact N-OD1 3.36Å; D543-N556 PolarHBondContact O-N 2.99Å; N556-Y558 PolarHBondContact O-N 3.43Å
557A96.1Very high95.3Very high17 Ų1719.9 Ų19.914%0.1410%0.098CC..  trans-58.7-30.2169.600000111.5M482 D543 D546 L559M482-A557 HydrophobicContact CG-CB 4.14Å; D543-A557 WeakPolarHBondContact OD1-CB 3.44Å; D543-A557 PolarHBondContact OD1-N 3.02Å; D543-A557 PolarHBondContact OD2-N 3.08Å; D546-A557 HydrophobicContact CB-CB 3.79Å; A557-L559 PolarHBondContact O-N 2.81Å
558Y96.4Very high95.4Very high4 Ų419.8 Ų19.82%0.01610%0.098CC..  trans-61.6126.7170.8-173.2-92.2000112.4F82 M482 R523 H542 D543 N556 I560 H561 T563 W566 D626F82-Y558 AromaticContact CE2-CD2 4Å; F82-Y558 HydrophobicContact CE2-CD2 4Å; M482-Y558 HydrophobicContact SD-CD2 3.97Å; M482-Y558 HydrophobicContact SD-CG 4.38Å; R523-Y558 PolarHBondContact NH1-O 3.38Å; R523-Y558 PolarHBondContact NH2-O 3.2Å; R523-Y558 VanDerWaalsContact NH2-O 3.09Å; H542-Y558 VanDerWaalsContact CE1-CB 3.47Å; H542-Y558 WeakPolarHBondContact CE1-CB 3.32Å; H542-Y558 AromaticContact CE1-CD2 3.71Å; H542-Y558 AromaticContact CE1-CG 3.61Å; H542-Y558 WeakPolarHBondContact ND1-CB 3.49Å; H542-Y558 AromaticContact ND1-CG 3.77Å; H542-Y558 AromaticContact NE2-CD2 3.98Å; H542-Y558 AromaticContact NE2-CG 3.95Å; D543-Y558 WeakPolarHBondContact OD2-CB 3.34Å; D543-Y558 PolarHBondContact OD2-N 2.99Å; N556-Y558 PolarHBondContact O-N 3.43Å; Y558-I560 HydrophobicContact CD2-CG1 4.48Å; Y558-I560 HydrophobicContact CE1-CB 4.12Å; Y558-I560 HydrophobicContact CE2-CB 4.02Å; Y558-I560 HydrophobicContact CE2-CG1 3.94Å; Y558-H561 HydrophobicContact CE1-CB 3.95Å; Y558-H561 VanDerWaalsContact CE1-N 3.34Å; Y558-H561 PolarHBondContact OH-CD2 3.22Å; Y558-T563 HydrophobicContact CD1-CG2 3.63Å; Y558-T563 HydrophobicContact CE1-CG2 3.83Å; Y558-W566 HydrophobicContact CE1-CH2 4.38Å; Y558-W566 HydrophobicContact CE1-CZ2 4.02Å; Y558-D626 WeakPolarHBondContact OH-CB 3.48Å; Y558-D626 PolarHBondContact OH-OD2 3.26Å
559L94.8Very high95.7Very high26 Ų2618.7 Ų18.714%0.1369%0.092CC..  trans-140.414-177.258.780.5000113.7W69 F82 H525 L526 A557W69-L559 HydrophobicContact CD2-CD1 4.49Å; W69-L559 HydrophobicContact CZ2-CD2 4.37Å; F82-L559 HydrophobicContact CE1-CD1 3.88Å; F82-L559 HydrophobicContact CE1-CD2 4.11Å; F82-L559 HydrophobicContact CE1-CG 3.61Å; F82-L559 HydrophobicContact CZ-CD1 4.12Å; F82-L559 HydrophobicContact CZ-CG 3.94Å; H525-L559 WeakPolarHBondContact CA-O 3.37Å; L526-L559 HydrophobicContact CD1-CD1 3.33Å; L526-L559 HydrophobicContact CD2-CD1 4.13Å; L526-L559 HydrophobicContact CG-CD1 3.41Å; L526-L559 VanDerWaalsContact CG-CD1 3.41Å; L526-L559 PolarHBondContact N-O 2.9Å; A557-L559 PolarHBondContact O-N 2.81Å
560I94.5Very high95.8Very high7 Ų717.4 Ų17.44%0.0369%0.085CC..SBendtrans-67-53.7173.3-53.4-64.8000108.7L62 Y66 F82 M85 L526 M527 Y558L62-I560 HydrophobicContact CD1-CG2 4.37Å; Y66-I560 HydrophobicContact CD2-CD1 4.27Å; Y66-I560 HydrophobicContact CE2-CD1 4.49Å; F82-I560 HydrophobicContact CE2-CG1 4.19Å; F82-I560 HydrophobicContact CZ-CD1 3.97Å; F82-I560 HydrophobicContact CZ-CG1 3.98Å; M85-I560 HydrophobicContact CE-CD1 4.12Å; L526-I560 HydrophobicContact CB-CD1 4.47Å; L526-I560 HydrophobicContact CD1-CD1 4.03Å; L526-I560 PolarHBondContact N-O 2.96Å; M527-I560 HydrophobicContact CB-CG2 4.27Å; M527-I560 WeakPolarHBondContact CB-O 3.35Å; M527-I560 HydrophobicContact CE-CG2 4.24Å; M527-I560 PolarHBondContact N-O 3.27Å; Y558-I560 HydrophobicContact CD2-CG1 4.48Å; Y558-I560 HydrophobicContact CE1-CB 4.12Å; Y558-I560 HydrophobicContact CE2-CB 4.02Å; Y558-I560 HydrophobicContact CE2-CG1 3.94Å
561H94.4Very high96Very high9 Ų917.4 Ų17.44%0.0429%0.085CC..SBendtrans-106.7162.2172.2-63.9-113.8000110.9H525 M527 Y558 W566 A621 D626H525-H561 PolarHBondContact CE1-O 3.13Å; H525-H561 PolarHBondContact ND1-O 2.96Å; M527-H561 WeakPolarHBondContact CE-NE2 3.2Å; Y558-H561 HydrophobicContact CE1-CB 3.95Å; Y558-H561 VanDerWaalsContact CE1-N 3.34Å; Y558-H561 PolarHBondContact OH-CD2 3.22Å; H561-W566 HydrophobicContact CB-CZ2 4.28Å; H561-A621 PolarHBondContact ND1-O 3.32Å; H561-A621 VanDerWaalsContact ND1-O 3.15Å; H561-D626 PolarHBondContact CE1-O 2.82Å; H561-D626 PolarHBondContact NE2-O 3.12Å
562D94.6Very high96.2Very high23 Ų2317.3 Ų17.312%0.1238%0.084CC..  trans-79.7122.3157.5-177.68.9000107.8H525 A564 W566H525-D562 VanDerWaalsContact CE1-CA 3.43Å; H525-D562 WeakPolarHBondContact CE1-CA 3.29Å; H525-D562 WeakPolarHBondContact ND1-CA 3.47Å; H525-D562 PolarHBondContact ND1-N 3.02Å; D562-A564 VanDerWaalsContact OD1-CB 3.3Å; D562-A564 WeakPolarHBondContact OD1-CB 3.4Å; D562-A564 PolarHBondContact OD1-N 2.97Å; D562-W566 PolarHBondContact O-NE1 3Å
563T95.4Very high96.4Very high1 Ų116.9 Ų16.91%0.0068%0.083CC..  trans-95.7-5.2-176.3580000112H542 Y558 D565 W566H542-T563 HydrophobicContact CB-CG2 3.84Å; Y558-T563 HydrophobicContact CD1-CG2 3.63Å; Y558-T563 HydrophobicContact CE1-CG2 3.83Å; T563-D565 PolarHBondContact O-N 3.26Å; T563-W566 HydrophobicContact CG2-CD2 4.01Å; T563-W566 HydrophobicContact CG2-CE3 4.48Å; T563-W566 HydrophobicContact CG2-CG 4.41Å; T563-W566 HydrophobicContact CG2-CH2 4.42Å; T563-W566 HydrophobicContact CG2-CZ2 3.98Å; T563-W566 WeakPolarHBondContact O-CB 3.41Å; T563-W566 PolarHBondContact O-N 2.72Å; T563-W566 VanDerWaalsContact O-N 3.13Å
564A94.8Very high96.6Very high10 Ų1013.4 Ų13.48%0.0837%0.066CC..THydrogen-bonded Turntrans-63.1-23.4177.600000113.3T536 D562T536-A564 WeakPolarHBondContact OG1-CB 3.5Å; D562-A564 VanDerWaalsContact OD1-CB 3.3Å; D562-A564 WeakPolarHBondContact OD1-CB 3.4Å; D562-A564 PolarHBondContact OD1-N 2.97Å
565D94Very high96.8Very high55 Ų558.3 Ų8.329%0.2945%0.047SC..THydrogen-bonded Turntrans-107.410.7178.2-76.7-18.9000113.7T563 K567 K606 F607 Y620T563-D565 PolarHBondContact O-N 3.26Å; D565-K567 PolarHBondContact O-NZ 2.83Å; D565-K606 IonicContact OD1-NZ 3.94Å; D565-K606 PolarHBondContact OD1-NZ 3.34Å; D565-F607 HydrophobicContact CB-CE1 4.32Å; D565-F607 HydrophobicContact CB-CZ 4.17Å; D565-Y620 WeakPolarHBondContact CB-OH 3.27Å
566W97.5Very high96.9Very high3 Ų37.7 Ų7.71%0.0114%0.044CC..  trans-68.7134175.5-80.824.2000111.2H542 Y558 H561 D562 T563 L569 D622 D626H542-W566 AromaticContact CD2-CH2 3.93Å; H542-W566 AromaticContact CD2-CZ3 3.72Å; Y558-W566 HydrophobicContact CE1-CH2 4.38Å; Y558-W566 HydrophobicContact CE1-CZ2 4.02Å; H561-W566 HydrophobicContact CB-CZ2 4.28Å; D562-W566 PolarHBondContact O-NE1 3Å; T563-W566 HydrophobicContact CG2-CD2 4.01Å; T563-W566 HydrophobicContact CG2-CE3 4.48Å; T563-W566 HydrophobicContact CG2-CG 4.41Å; T563-W566 HydrophobicContact CG2-CH2 4.42Å; T563-W566 HydrophobicContact CG2-CZ2 3.98Å; T563-W566 WeakPolarHBondContact O-CB 3.41Å; T563-W566 PolarHBondContact O-N 2.72Å; T563-W566 VanDerWaalsContact O-N 3.13Å; W566-L569 HydrophobicContact CB-CD1 4.05Å; W566-L569 HydrophobicContact CB-CG 4.37Å; W566-L569 HydrophobicContact CE3-CD1 4.11Å; W566-L569 HydrophobicContact CE3-CG 4.21Å; W566-D622 CarbonylContact C-O 3.6Å; W566-D622 WeakPolarHBondContact CA-O 3.42Å; W566-D626 HydrophobicContact CH2-CB 3.86Å; W566-D626 HydrophobicContact CZ2-CB 3.87Å
567K97.8Very high97Very high0 Ų07.4 Ų7.40%04%0.042CC..SBendtrans-82-13.4-171.9-54.6-55.9-177.7-70.30113.7D565 L571 F607 I615 E616 N617 S618 D622 C637D565-K567 PolarHBondContact O-NZ 2.83Å; K567-L571 WeakPolarHBondContact O-CD1 3.3Å; K567-L571 VanDerWaalsContact O-CG 3.28Å; K567-L571 WeakPolarHBondContact O-CG 3.3Å; K567-F607 HydrophobicContact CD-CB 4.15Å; K567-F607 HydrophobicContact CD-CD1 3.99Å; K567-F607 HydrophobicContact CD-CD2 3.43Å; K567-F607 VanDerWaalsContact CD-CD2 3.43Å; K567-F607 HydrophobicContact CD-CE1 4.11Å; K567-F607 HydrophobicContact CD-CE2 3.6Å; K567-F607 HydrophobicContact CD-CG 3.62Å; K567-F607 HydrophobicContact CD-CZ 3.92Å; K567-I615 HydrophobicContact CB-CD1 4.18Å; K567-E616 WeakPolarHBondContact CE-O 3.49Å; K567-N617 WeakPolarHBondContact CG-ND2 3.44Å; K567-S618 PolarHBondContact NZ-OG 3.23Å; K567-S618 VanDerWaalsContact NZ-OG 3.08Å; K567-D622 PolarHBondContact N-O 3.44Å; K567-D622 IonicContact NZ-OD2 2.74Å; K567-D622 PolarHBondContact NZ-OD2 3.36Å; K567-C637 HydrophobicContact CB-CB 3.95Å
568D98.4Very high97.2Very high0 Ų06.9 Ų6.90%04%0.037CC..SBendtrans-103.8-30.5-172.467.4-21.9000114.3N570 L571 K572 Q623 T624 Y636 M640D568-N570 PolarHBondContact O-N 2.78Å; D568-L571 PolarHBondContact O-N 2.95Å; D568-K572 HydrophobicContact CB-CD 4.19Å; D568-K572 VanDerWaalsContact O-CB 3.28Å; D568-K572 WeakPolarHBondContact O-CB 3.42Å; D568-K572 WeakPolarHBondContact O-CG 3.49Å; D568-K572 PolarHBondContact O-N 3.26Å; D568-K572 WeakPolarHBondContact OD2-CE 3.35Å; D568-K572 IonicContact OD2-NZ 2.83Å; D568-K572 PolarHBondContact OD2-NZ 2.84Å; D568-Q623 HydrophobicContact CB-CB 4.16Å; D568-Q623 WeakPolarHBondContact OD1-CA 3.25Å; D568-T624 WeakPolarHBondContact OD2-CB 3.26Å; D568-T624 PolarHBondContact OD2-N 2.84Å; D568-Y636 HydrophobicContact CB-CE1 4.27Å; D568-Y636 PolarHBondContact OD2-OH 3.32Å; D568-M640 HydrophobicContact CB-CE 3.5Å; D568-M640 HydrophobicContact CB-SD 4.31Å
569L98.4Very high97.3Very high0 Ų06.7 Ų6.70%04%0.036CC..Hα-helixtrans-56.8-52.1-174.4-74.7170.3000113.3Y486 D487 V540 H542 W566 L571 K572 F573Y486-L569 HydrophobicContact CD1-CD2 4.49Å; D487-L569 HydrophobicContact CB-CD2 3.74Å; V540-L569 HydrophobicContact CB-CB 4.22Å; V540-L569 HydrophobicContact CG1-CB 4.39Å; H542-L569 HydrophobicContact CB-CD1 4.3Å; W566-L569 HydrophobicContact CB-CD1 4.05Å; W566-L569 HydrophobicContact CB-CG 4.37Å; W566-L569 HydrophobicContact CE3-CD1 4.11Å; W566-L569 HydrophobicContact CE3-CG 4.21Å; L569-L571 VanDerWaalsContact C-N 3.34Å; L569-L571 PolarHBondContact O-N 3.04Å; L569-K572 PolarHBondContact O-N 2.96Å; L569-F573 PolarHBondContact O-N 3.3Å
570N98.8Very high97.4Very high0 Ų05.5 Ų5.50%03%0.03CC..Hα-helixtrans-63.8-40179.3-81-13.3000112.2V540 D568 F573 V574 V600 S603 E604V540-N570 VanDerWaalsContact CG2-OD1 3.31Å; V540-N570 WeakPolarHBondContact CG2-OD1 3.5Å; V540-N570 PolarHBondContact N-OD1 2.84Å; D568-N570 PolarHBondContact O-N 2.78Å; N570-F573 WeakPolarHBondContact O-CB 3.46Å; N570-F573 PolarHBondContact O-N 2.82Å; N570-V574 WeakPolarHBondContact O-CG2 3.48Å; N570-V574 PolarHBondContact O-N 2.58Å; N570-V600 HydrophobicContact CB-CB 3.92Å; N570-V600 HydrophobicContact CB-CG2 4.44Å; N570-S603 PolarHBondContact ND2-OG 3.32Å; N570-E604 HydrophobicContact CB-CG 3.76Å; N570-E604 VanDerWaalsContact CB-OE1 3.31Å; N570-E604 WeakPolarHBondContact CB-OE1 3.24Å; N570-E604 PolarHBondContact ND2-OE1 2.91Å
571L98.8Very high97.6Very high0 Ų05.7 Ų5.70%03%0.03CC..Hα-helixtrans-67.9-43.8179.4-53.6-176.1000111.2K567 D568 L569 F573 V574 L575 M601 E604 I615 M640 W641 S644K567-L571 WeakPolarHBondContact O-CD1 3.3Å; K567-L571 VanDerWaalsContact O-CG 3.28Å; K567-L571 WeakPolarHBondContact O-CG 3.3Å; D568-L571 PolarHBondContact O-N 2.95Å; L569-L571 VanDerWaalsContact C-N 3.34Å; L569-L571 PolarHBondContact O-N 3.04Å; L571-F573 PolarHBondContact O-N 3.29Å; L571-V574 PolarHBondContact O-N 3.18Å; L571-L575 WeakPolarHBondContact O-CB 3.37Å; L571-L575 VanDerWaalsContact O-CG 3.25Å; L571-L575 WeakPolarHBondContact O-CG 3.16Å; L571-L575 PolarHBondContact O-N 2.89Å; L571-M601 HydrophobicContact CD2-SD 4.15Å; L571-E604 HydrophobicContact CD2-CG 4Å; L571-I615 HydrophobicContact CD1-CD1 3.86Å; L571-M640 HydrophobicContact CB-CB 4.21Å; L571-M640 HydrophobicContact CD1-CB 3.98Å; L571-W641 HydrophobicContact CD1-CB 3.95Å; L571-W641 HydrophobicContact CD2-CE3 3.69Å; L571-W641 HydrophobicContact CD2-CZ3 4.29Å; L571-S644 WeakPolarHBondContact CA-OG 3.47Å; L571-S644 WeakPolarHBondContact CB-OG 3.44Å; L571-S644 PolarHBondContact O-OG 3.38Å
572K98.8Very high97.8Very high0 Ų07.9 Ų7.90%04%0.041CC..Hα-helixtrans-60.3-33.7174.3-73.4174.3169.1175.10112D487 F490 D568 L569 Q576 Y636 M640D487-K572 HydrophobicContact CB-CD 4.15Å; D487-K572 PolarHBondContact O-NZ 3.1Å; F490-K572 HydrophobicContact CB-CB 4.3Å; F490-K572 HydrophobicContact CB-CD 3.78Å; F490-K572 HydrophobicContact CB-CG 4.07Å; F490-K572 HydrophobicContact CD1-CD 4.4Å; F490-K572 HydrophobicContact CD1-CG 4.41Å; F490-K572 HydrophobicContact CD2-CB 3.75Å; F490-K572 HydrophobicContact CD2-CD 4.17Å; F490-K572 HydrophobicContact CD2-CG 3.52Å; F490-K572 HydrophobicContact CE2-CB 4.38Å; F490-K572 HydrophobicContact CE2-CG 3.94Å; F490-K572 HydrophobicContact CG-CB 4.25Å; F490-K572 HydrophobicContact CG-CD 3.88Å; F490-K572 HydrophobicContact CG-CG 3.75Å; D568-K572 HydrophobicContact CB-CD 4.19Å; D568-K572 VanDerWaalsContact O-CB 3.28Å; D568-K572 WeakPolarHBondContact O-CB 3.42Å; D568-K572 WeakPolarHBondContact O-CG 3.49Å; D568-K572 PolarHBondContact O-N 3.26Å; D568-K572 WeakPolarHBondContact OD2-CE 3.35Å; D568-K572 IonicContact OD2-NZ 2.83Å; D568-K572 PolarHBondContact OD2-NZ 2.84Å; L569-K572 PolarHBondContact O-N 2.96Å; K572-Q576 VanDerWaalsContact O-CB 3.28Å; K572-Q576 WeakPolarHBondContact O-CB 3.32Å; K572-Q576 VanDerWaalsContact O-CG 3.24Å; K572-Q576 WeakPolarHBondContact O-CG 3.49Å; K572-Q576 PolarHBondContact O-N 3.48Å; K572-Q576 PolarHBondContact O-NE2 3.25Å; K572-Q576 VanDerWaalsContact O-NE2 3.13Å; K572-Y636 WeakPolarHBondContact CE-OH 3.27Å; K572-Y636 PolarHBondContact NZ-OH 3.37Å; K572-M640 HydrophobicContact CG-SD 4Å
573F98.9Very high97.9Very high0 Ų09.7 Ų9.70%05%0.05CC..Hα-helixtrans-64.8-52.7174.4175.2-94.2000111.4Y486 I511 A512 V540 L569 N570 L571 L575 Q576 V577 M593 I596 V600Y486-F573 HydrophobicContact CE1-CB 3.69Å; Y486-F573 HydrophobicContact CE1-CD2 4.23Å; Y486-F573 HydrophobicContact CE1-CG 4.49Å; Y486-F573 AromaticContact CZ-CD2 3.89Å; Y486-F573 WeakPolarHBondContact OH-CA 3.31Å; Y486-F573 VanDerWaalsContact OH-CD2 3.29Å; Y486-F573 WeakPolarHBondContact OH-CD2 3.32Å; I511-F573 HydrophobicContact CG2-CD2 3.78Å; I511-F573 HydrophobicContact CG2-CE2 4Å; A512-F573 HydrophobicContact CB-CE2 3.96Å; A512-F573 HydrophobicContact CB-CZ 3.76Å; V540-F573 HydrophobicContact CG2-CB 3.56Å; V540-F573 HydrophobicContact CG2-CD1 4.45Å; V540-F573 HydrophobicContact CG2-CD2 4.17Å; V540-F573 HydrophobicContact CG2-CG 3.82Å; L569-F573 PolarHBondContact O-N 3.3Å; N570-F573 WeakPolarHBondContact O-CB 3.46Å; N570-F573 PolarHBondContact O-N 2.82Å; L571-F573 PolarHBondContact O-N 3.29Å; F573-L575 VanDerWaalsContact C-N 3.31Å; F573-L575 PolarHBondContact O-N 2.93Å; F573-Q576 PolarHBondContact O-N 2.76Å; F573-V577 HydrophobicContact CD1-CG2 4.21Å; F573-V577 HydrophobicContact CD2-CG2 4.42Å; F573-V577 HydrophobicContact CE1-CG2 3.83Å; F573-V577 HydrophobicContact CE2-CG2 4.04Å; F573-V577 HydrophobicContact CG-CG2 4.49Å; F573-V577 HydrophobicContact CZ-CG2 3.72Å; F573-V577 WeakPolarHBondContact O-CG2 3.14Å; F573-V577 PolarHBondContact O-N 3.11Å; F573-M593 HydrophobicContact CZ-SD 4.06Å; F573-I596 HydrophobicContact CE1-CB 4.29Å; F573-I596 HydrophobicContact CE1-CG2 3.75Å; F573-I596 HydrophobicContact CZ-CB 4.37Å; F573-I596 HydrophobicContact CZ-CG2 3.76Å; F573-V600 HydrophobicContact CD1-CG2 4.14Å
574V98.9Very high98Very high0 Ų011.8 Ų11.80%06%0.063CC..Hα-helixtrans-58.8-44.1179.8171.60000111.5N570 L571 Y578 C597 V600 M601 V647 M648 M651N570-V574 WeakPolarHBondContact O-CG2 3.48Å; N570-V574 PolarHBondContact O-N 2.58Å; L571-V574 PolarHBondContact O-N 3.18Å; V574-Y578 PolarHBondContact O-N 3.01Å; V574-C597 HydrophobicContact CG2-CB 4.17Å; V574-V600 HydrophobicContact CG2-CG2 3.48Å; V574-V600 VanDerWaalsContact CG2-CG2 3.48Å; V574-M601 HydrophobicContact CG1-SD 4.39Å; V574-M601 HydrophobicContact CG2-CG 3.91Å; V574-M601 HydrophobicContact CG2-SD 3.96Å; V574-V647 HydrophobicContact CG1-CG2 3.55Å; V574-M648 HydrophobicContact CG1-CG 3.91Å; V574-M648 HydrophobicContact CG1-SD 3.68Å; V574-M651 HydrophobicContact CG1-CE 4.05Å
575L98.8Very high98.1Very high0 Ų016.8 Ų16.80%08%0.084CC..Hα-helixtrans-61.7-49.9176.7-71.9174000111.8F490 L571 F573 Y578 R579 M640 A643 V647 F708F490-L575 HydrophobicContact CE2-CB 4.34Å; F490-L575 HydrophobicContact CE2-CD1 4.12Å; L571-L575 WeakPolarHBondContact O-CB 3.37Å; L571-L575 VanDerWaalsContact O-CG 3.25Å; L571-L575 WeakPolarHBondContact O-CG 3.16Å; L571-L575 PolarHBondContact O-N 2.89Å; F573-L575 VanDerWaalsContact C-N 3.31Å; F573-L575 PolarHBondContact O-N 2.93Å; L575-Y578 PolarHBondContact O-N 3.48Å; L575-R579 PolarHBondContact O-N 3.47Å; L575-M640 HydrophobicContact CD1-CB 4.4Å; L575-M640 HydrophobicContact CD1-CG 4.32Å; L575-A643 HydrophobicContact CD1-CB 4.39Å; L575-A643 HydrophobicContact CD2-CB 3.76Å; L575-V647 HydrophobicContact CD2-CG1 4.12Å; L575-V647 HydrophobicContact CD2-CG2 4.15Å; L575-F708 VanDerWaalsContact C-CE1 3.41Å; L575-F708 HydrophobicContact CB-CD1 3.6Å; L575-F708 HydrophobicContact CB-CE1 3.84Å; L575-F708 HydrophobicContact CB-CG 4.24Å; L575-F708 HydrophobicContact CD1-CB 4.36Å; L575-F708 HydrophobicContact CD2-CD1 4.41Å; L575-F708 HydrophobicContact CG-CD1 4.43Å; L575-F708 VanDerWaalsContact O-CE1 3.29Å; L575-F708 WeakPolarHBondContact O-CE1 3.44Å
576Q98.8Very high98.3Very high0 Ų016.2 Ų16.20%08%0.081CC..Hα-helixtrans-62.9-43.8179.3-76.7177.910300112.2Y486 H489 F490 S493 Q508 K572 F573 Y578 R579 D580 F708Y486-Q576 PolarHBondContact OH-NE2 3.45Å; H489-Q576 PolarHBondContact CD2-OE1 2.7Å; H489-Q576 VanDerWaalsContact CD2-OE1 3.27Å; F490-Q576 HydrophobicContact CD2-CG 4.11Å; S493-Q576 PolarHBondContact OG-OE1 2.82Å; Q508-Q576 VanDerWaalsContact NE2-CB 3.34Å; K572-Q576 VanDerWaalsContact O-CB 3.28Å; K572-Q576 WeakPolarHBondContact O-CB 3.32Å; K572-Q576 VanDerWaalsContact O-CG 3.24Å; K572-Q576 WeakPolarHBondContact O-CG 3.49Å; K572-Q576 PolarHBondContact O-N 3.48Å; K572-Q576 PolarHBondContact O-NE2 3.25Å; K572-Q576 VanDerWaalsContact O-NE2 3.13Å; F573-Q576 PolarHBondContact O-N 2.76Å; Q576-Y578 VanDerWaalsContact C-N 3.3Å; Q576-Y578 PolarHBondContact O-N 3.45Å; Q576-R579 PolarHBondContact O-N 3.27Å; Q576-D580 WeakPolarHBondContact O-CB 3.31Å; Q576-D580 PolarHBondContact O-N 3.46Å; Q576-F708 HydrophobicContact CB-CZ 4.47Å; Q576-F708 HydrophobicContact CG-CE1 4.24Å; Q576-F708 HydrophobicContact CG-CE2 4.48Å; Q576-F708 HydrophobicContact CG-CZ 3.63Å
577V98.8Very high98.3Very high0 Ų019 Ų190%010%0.101CC..Hα-helixtrans-53.4-49.6175.3165.40000110.8F573 D580 F581 Y589 M593 M651F573-V577 HydrophobicContact CD1-CG2 4.21Å; F573-V577 HydrophobicContact CD2-CG2 4.42Å; F573-V577 HydrophobicContact CE1-CG2 3.83Å; F573-V577 HydrophobicContact CE2-CG2 4.04Å; F573-V577 HydrophobicContact CG-CG2 4.49Å; F573-V577 HydrophobicContact CZ-CG2 3.72Å; F573-V577 WeakPolarHBondContact O-CG2 3.14Å; F573-V577 PolarHBondContact O-N 3.11Å; V577-D580 PolarHBondContact O-N 3.14Å; V577-F581 WeakPolarHBondContact O-CB 3.31Å; V577-F581 PolarHBondContact O-N 3.41Å; V577-Y589 HydrophobicContact CG1-CE1 4.14Å; V577-M593 HydrophobicContact CG1-CB 3.5Å; V577-M593 VanDerWaalsContact CG1-CB 3.5Å; V577-M593 HydrophobicContact CG1-CG 4.01Å; V577-M593 HydrophobicContact CG2-CB 4.17Å; V577-M593 HydrophobicContact CG2-CG 4.2Å; V577-M593 HydrophobicContact CG2-SD 4.25Å; V577-M651 HydrophobicContact CG1-SD 4.35Å
578Y98.7Very high98.2Very high6 Ų623.2 Ų23.22%0.02412%0.121CC..Hα-helixtrans-68.6-40.5-178.6-179-101.1000112.6V574 L575 Q576 D580 F581 H582 V647 K650 M651 L654 L714V574-Y578 PolarHBondContact O-N 3.01Å; L575-Y578 PolarHBondContact O-N 3.48Å; Q576-Y578 VanDerWaalsContact C-N 3.3Å; Q576-Y578 PolarHBondContact O-N 3.45Å; Y578-D580 VanDerWaalsContact C-N 3.34Å; Y578-D580 PolarHBondContact O-N 3.4Å; Y578-F581 HydrophobicContact CD2-CD1 4.16Å; Y578-F581 HydrophobicContact CE2-CD1 4.05Å; Y578-F581 HydrophobicContact CE2-CE1 4.33Å; Y578-F581 PolarHBondContact O-N 2.93Å; Y578-H582 WeakPolarHBondContact O-CB 3.47Å; Y578-H582 PolarHBondContact O-N 2.7Å; Y578-V647 HydrophobicContact CD1-CB 3.85Å; Y578-V647 HydrophobicContact CD1-CG1 3.44Å; Y578-V647 VanDerWaalsContact CD1-CG1 3.44Å; Y578-V647 HydrophobicContact CD2-CB 4.44Å; Y578-V647 HydrophobicContact CE1-CG1 4.19Å; Y578-V647 HydrophobicContact CG-CB 3.73Å; Y578-V647 HydrophobicContact CG-CG1 3.86Å; Y578-K650 HydrophobicContact CE2-CB 4.18Å; Y578-K650 HydrophobicContact CE2-CG 3.58Å; Y578-K650 VanDerWaalsContact OH-CG 3.31Å; Y578-K650 WeakPolarHBondContact OH-CG 3.12Å; Y578-M651 HydrophobicContact CD2-CG 3.49Å; Y578-M651 VanDerWaalsContact CD2-CG 3.49Å; Y578-M651 HydrophobicContact CD2-SD 4.13Å; Y578-M651 HydrophobicContact CE2-CG 4.23Å; Y578-M651 HydrophobicContact CG-CG 4.33Å; Y578-L654 HydrophobicContact CE2-CD1 4.04Å; Y578-L714 HydrophobicContact CD1-CD1 4.33Å; Y578-L714 HydrophobicContact CE1-CD1 3.78Å; Y578-L714 HydrophobicContact CE1-CD2 4.22Å; Y578-L714 HydrophobicContact CE1-CG 3.82Å
579R98.5Very high98.2Very high0 Ų023.2 Ų23.20%012%0.121CC..Hα-helixtrans-59.1-46.5174-176.9-159.764-164.5-5.8111.2S493 L575 Q576 H582 L583 F708 S712S493-R579 VanDerWaalsContact OG-CZ 3.3Å; S493-R579 PolarHBondContact OG-NH1 2.81Å; S493-R579 PolarHBondContact OG-NH2 2.94Å; L575-R579 PolarHBondContact O-N 3.47Å; Q576-R579 PolarHBondContact O-N 3.27Å; R579-H582 WeakPolarHBondContact O-CB 3.44Å; R579-H582 PolarHBondContact O-N 2.97Å; R579-H582 VanDerWaalsContact O-N 3.09Å; R579-L583 HydrophobicContact CG-CD1 4Å; R579-L583 HydrophobicContact CG-CG 4.45Å; R579-L583 WeakPolarHBondContact O-CG 3.32Å; R579-L583 PolarHBondContact O-N 2.88Å; R579-F708 HydrophobicContact CB-CD1 4.39Å; R579-F708 HydrophobicContact CB-CE1 3.59Å; R579-F708 HydrophobicContact CB-CZ 4.26Å; R579-F708 HydrophobicContact CG-CE1 4.19Å; R579-S712 WeakPolarHBondContact CA-OG 3.48Å; R579-S712 WeakPolarHBondContact CB-OG 3.04Å
580D98.7Very high98.1Very high1 Ų123.6 Ų23.61%0.00512%0.123CC..Hα-helixtrans-67-40.9-176-64.8-8.1000110.5I497 L505 Q508 Q576 V577 Y578 L583 T584 Y589I497-D580 HydrophobicContact CD1-CB 3.75Å; I497-D580 HydrophobicContact CG1-CB 4.26Å; I497-D580 WeakPolarHBondContact CG1-OD1 3.42Å; L505-D580 HydrophobicContact CD2-CB 3.87Å; Q508-D580 WeakPolarHBondContact CG-OD2 3.46Å; Q576-D580 WeakPolarHBondContact O-CB 3.31Å; Q576-D580 PolarHBondContact O-N 3.46Å; V577-D580 PolarHBondContact O-N 3.14Å; Y578-D580 VanDerWaalsContact C-N 3.34Å; Y578-D580 PolarHBondContact O-N 3.4Å; D580-L583 PolarHBondContact O-N 3.2Å; D580-T584 WeakPolarHBondContact O-CB 3.29Å; D580-T584 VanDerWaalsContact O-CG2 3.29Å; D580-T584 WeakPolarHBondContact O-CG2 3.41Å; D580-T584 PolarHBondContact O-N 3.23Å; D580-T584 PolarHBondContact O-OG1 3.33Å; D580-Y589 HydrophobicContact CB-CE1 4.18Å
581F98.6Very high98Very high12 Ų1230 Ų305%0.05315%0.147CC..Hα-helixtrans-58.2-47.4167.3163.1-102.5000111.7V577 Y578 L583 T584 Q585 D586 Y589 L590 L654V577-F581 WeakPolarHBondContact O-CB 3.31Å; V577-F581 PolarHBondContact O-N 3.41Å; Y578-F581 HydrophobicContact CD2-CD1 4.16Å; Y578-F581 HydrophobicContact CE2-CD1 4.05Å; Y578-F581 HydrophobicContact CE2-CE1 4.33Å; Y578-F581 PolarHBondContact O-N 2.93Å; F581-L583 VanDerWaalsContact C-N 3.29Å; F581-L583 PolarHBondContact O-N 2.98Å; F581-T584 PolarHBondContact O-N 2.91Å; F581-Q585 VanDerWaalsContact O-CA 3.22Å; F581-Q585 WeakPolarHBondContact O-CA 3.32Å; F581-Q585 PolarHBondContact O-N 3.03Å; F581-D586 WeakPolarHBondContact CD2-O 3.41Å; F581-Y589 HydrophobicContact CB-CD1 4.29Å; F581-Y589 HydrophobicContact CB-CE1 4.48Å; F581-L590 HydrophobicContact CB-CB 4.46Å; F581-L590 HydrophobicContact CD1-CD2 4.12Å; F581-L590 HydrophobicContact CD2-CB 3.63Å; F581-L590 HydrophobicContact CD2-CD2 3.99Å; F581-L590 HydrophobicContact CD2-CG 4.3Å; F581-L590 HydrophobicContact CE1-CD2 3.98Å; F581-L590 HydrophobicContact CE2-CB 4.08Å; F581-L590 HydrophobicContact CE2-CD2 3.81Å; F581-L590 HydrophobicContact CG-CB 4.04Å; F581-L590 HydrophobicContact CG-CD1 4.3Å; F581-L590 HydrophobicContact CG-CD2 4.12Å; F581-L590 HydrophobicContact CG-CG 4.38Å; F581-L590 HydrophobicContact CZ-CD2 3.81Å; F581-L654 HydrophobicContact CD1-CD1 4.32Å; F581-L654 HydrophobicContact CE1-CD1 3.49Å; F581-L654 VanDerWaalsContact CE1-CD1 3.49Å; F581-L654 HydrophobicContact CZ-CD1 4.02Å
582H97.4Very high98Very high55 Ų5530.7 Ų30.726%0.25515%0.151SC..Hα-helixtrans-60.9-38.1-178.6175.774.4000112.3Y578 R579 Q585 S712Y578-H582 WeakPolarHBondContact O-CB 3.47Å; Y578-H582 PolarHBondContact O-N 2.7Å; R579-H582 WeakPolarHBondContact O-CB 3.44Å; R579-H582 PolarHBondContact O-N 2.97Å; R579-H582 VanDerWaalsContact O-N 3.09Å; H582-Q585 PolarHBondContact O-NE2 3.27Å; H582-S712 VanDerWaalsContact CD2-C 3.49Å; H582-S712 PolarHBondContact CD2-O 2.91Å; H582-S712 PolarHBondContact ND1-O 3.25Å
583L97.3Very high97.9Very high61 Ų6130.7 Ų30.732%0.31915%0.151SC..Hα-helixtrans-79.5-30.9-179.8-66.3176.1000113I497 R579 D580 F581 L837I497-L583 HydrophobicContact CB-CD1 4.5Å; I497-L583 HydrophobicContact CG1-CB 4.28Å; I497-L583 HydrophobicContact CG1-CD1 3.91Å; I497-L583 HydrophobicContact CG2-CD1 3.72Å; R579-L583 HydrophobicContact CG-CD1 4Å; R579-L583 HydrophobicContact CG-CG 4.45Å; R579-L583 WeakPolarHBondContact O-CG 3.32Å; R579-L583 PolarHBondContact O-N 2.88Å; D580-L583 PolarHBondContact O-N 3.2Å; F581-L583 VanDerWaalsContact C-N 3.29Å; F581-L583 PolarHBondContact O-N 2.98Å; L583-L837 HydrophobicContact CD2-CD1 4.06Å
584T97.9Very high97.9Very high44 Ų4432 Ų3227%0.2716%0.156SC..Hα-helixtrans-99.8-19.7-175.261.80000114I497 P501 L505 D580 F581 D586I497-T584 HydrophobicContact CD1-CG2 3.8Å; P501-T584 HydrophobicContact CB-CG2 4.04Å; L505-T584 HydrophobicContact CD1-CG2 4.22Å; D580-T584 WeakPolarHBondContact O-CB 3.29Å; D580-T584 VanDerWaalsContact O-CG2 3.29Å; D580-T584 WeakPolarHBondContact O-CG2 3.41Å; D580-T584 PolarHBondContact O-N 3.23Å; D580-T584 PolarHBondContact O-OG1 3.33Å; F581-T584 PolarHBondContact O-N 2.91Å; T584-D586 PolarHBondContact O-N 2.85Å; T584-D586 PolarHBondContact OG1-N 2.82Å
585Q97.1Very high97.9Very high116 Ų11633.5 Ų33.554%0.54217%0.166SC..  trans55.423.7-171.7-59.3-67-53.500113.5F581 H582 S587F581-Q585 VanDerWaalsContact O-CA 3.22Å; F581-Q585 WeakPolarHBondContact O-CA 3.32Å; F581-Q585 PolarHBondContact O-N 3.03Å; H582-Q585 PolarHBondContact O-NE2 3.27Å; Q585-S587 PolarHBondContact O-N 2.91Å
586D97.6Very high97.8Very high42 Ų4233.6 Ų33.623%0.22517%0.166CC..  trans-76.596-179-168.4-29.2000111.1F581 T584 Q588 Y589 L590F581-D586 WeakPolarHBondContact CD2-O 3.41Å; T584-D586 PolarHBondContact O-N 2.85Å; T584-D586 PolarHBondContact OG1-N 2.82Å; D586-Q588 VanDerWaalsContact C-N 3.28Å; D586-Q588 PolarHBondContact O-N 3.13Å; D586-Q588 PolarHBondContact OD1-N 3.48Å; D586-Y589 WeakPolarHBondContact O-CB 3.04Å; D586-Y589 PolarHBondContact O-N 2.78Å; D586-Y589 PolarHBondContact OD1-N 3.42Å; D586-L590 PolarHBondContact O-N 3.5Å; D586-L590 VanDerWaalsContact O-N 3.12Å
587S96.8Very high97.8Very high62 Ų6233.6 Ų33.643%0.43417%0.166SC..Hα-helixtrans-68.6-25.3-178.5-59.60000113.3Q585 R591Q585-S587 PolarHBondContact O-N 2.91Å; S587-R591 WeakPolarHBondContact O-CG 3.44Å; S587-R591 PolarHBondContact O-N 2.79Å; S587-R591 PolarHBondContact O-NH1 3.35Å
588Q96Very high97.8Very high89 Ų8936.7 Ų36.742%0.41618%0.18SC..Hα-helixtrans-73-44.8175.9-176.559.340.100109.9D586 L590 R591 D592D586-Q588 VanDerWaalsContact C-N 3.28Å; D586-Q588 PolarHBondContact O-N 3.13Å; D586-Q588 PolarHBondContact OD1-N 3.48Å; Q588-L590 VanDerWaalsContact C-N 3.3Å; Q588-L590 PolarHBondContact O-N 2.94Å; Q588-R591 PolarHBondContact O-N 3.47Å; Q588-R591 VanDerWaalsContact O-N 3.11Å; Q588-D592 PolarHBondContact NE2-OD1 3.26Å; Q588-D592 VanDerWaalsContact O-CG 3.31Å; Q588-D592 PolarHBondContact O-N 2.73Å
589Y98.1Very high97.8Very high0 Ų037.4 Ų37.40%019%0.188CC..Hα-helixtrans-53.6-47.5172.9172.1-100.2000111.7L505 Q508 Y509 V577 D580 F581 D586 R591 D592 M593L505-Y589 HydrophobicContact CD2-CD1 4.1Å; L505-Y589 HydrophobicContact CD2-CD2 3.89Å; L505-Y589 HydrophobicContact CD2-CE1 3.92Å; L505-Y589 HydrophobicContact CD2-CE2 3.69Å; L505-Y589 HydrophobicContact CD2-CG 4.08Å; Q508-Y589 HydrophobicContact CB-CE2 3.94Å; Q508-Y589 VanDerWaalsContact CB-OH 3.27Å; Q508-Y589 WeakPolarHBondContact CB-OH 3.49Å; Q508-Y589 WeakPolarHBondContact CG-OH 3.36Å; Y509-Y589 HydrophobicContact CD2-CD2 4.36Å; Y509-Y589 AromaticContact CE2-CD2 3.72Å; Y509-Y589 HydrophobicContact CE2-CD2 3.72Å; Y509-Y589 HydrophobicContact CE2-CE2 4.36Å; Y509-Y589 AromaticContact CZ-CD2 3.92Å; V577-Y589 HydrophobicContact CG1-CE1 4.14Å; D580-Y589 HydrophobicContact CB-CE1 4.18Å; F581-Y589 HydrophobicContact CB-CD1 4.29Å; F581-Y589 HydrophobicContact CB-CE1 4.48Å; D586-Y589 WeakPolarHBondContact O-CB 3.04Å; D586-Y589 PolarHBondContact O-N 2.78Å; D586-Y589 PolarHBondContact OD1-N 3.42Å; Y589-R591 VanDerWaalsContact C-N 3.33Å; Y589-R591 PolarHBondContact O-N 2.91Å; Y589-D592 PolarHBondContact O-N 3.25Å; Y589-M593 HydrophobicContact CD1-CG 4.38Å; Y589-M593 HydrophobicContact CD2-CE 3.85Å; Y589-M593 HydrophobicContact CD2-CG 3.92Å; Y589-M593 HydrophobicContact CE1-CG 4.07Å; Y589-M593 HydrophobicContact CE2-CE 3.38Å; Y589-M593 HydrophobicContact CE2-CG 3.58Å; Y589-M593 HydrophobicContact CE2-SD 4.04Å; Y589-M593 HydrophobicContact CG-CG 4.31Å; Y589-M593 WeakPolarHBondContact O-CB 3.11Å; Y589-M593 WeakPolarHBondContact O-CG 3.47Å; Y589-M593 PolarHBondContact O-N 3.18Å
590L98.3Very high97.8Very high7 Ų737.4 Ų37.44%0.03719%0.188CC..Hα-helixtrans-59.6-42.9177.2179.663.2000112.4F581 D586 Q588 M593 W594 M651 L654 V655F581-L590 HydrophobicContact CB-CB 4.46Å; F581-L590 HydrophobicContact CD1-CD2 4.12Å; F581-L590 HydrophobicContact CD2-CB 3.63Å; F581-L590 HydrophobicContact CD2-CD2 3.99Å; F581-L590 HydrophobicContact CD2-CG 4.3Å; F581-L590 HydrophobicContact CE1-CD2 3.98Å; F581-L590 HydrophobicContact CE2-CB 4.08Å; F581-L590 HydrophobicContact CE2-CD2 3.81Å; F581-L590 HydrophobicContact CG-CB 4.04Å; F581-L590 HydrophobicContact CG-CD1 4.3Å; F581-L590 HydrophobicContact CG-CD2 4.12Å; F581-L590 HydrophobicContact CG-CG 4.38Å; F581-L590 HydrophobicContact CZ-CD2 3.81Å; D586-L590 PolarHBondContact O-N 3.5Å; D586-L590 VanDerWaalsContact O-N 3.12Å; Q588-L590 VanDerWaalsContact C-N 3.3Å; Q588-L590 PolarHBondContact O-N 2.94Å; L590-M593 PolarHBondContact O-N 3.3Å; L590-W594 WeakPolarHBondContact O-CB 3.39Å; L590-W594 PolarHBondContact O-N 2.98Å; L590-M651 HydrophobicContact CD1-CB 4.36Å; L590-M651 HydrophobicContact CD1-CG 3.77Å; L590-M651 HydrophobicContact CD1-SD 3.62Å; L590-L654 HydrophobicContact CD2-CB 3.88Å; L590-L654 HydrophobicContact CD2-CD1 3.97Å; L590-V655 HydrophobicContact CD2-CG1 4.36Å; L590-V655 HydrophobicContact CG-CG1 4.35Å
591R96.6Very high97.7Very high134 Ų13437.4 Ų37.451%0.50619%0.188SC..Hα-helixtrans-64.6-41.3178-76.1-173-64.6-92.12.2112.3S587 Q588 Y589 M593 P595S587-R591 WeakPolarHBondContact O-CG 3.44Å; S587-R591 PolarHBondContact O-N 2.79Å; S587-R591 PolarHBondContact O-NH1 3.35Å; Q588-R591 PolarHBondContact O-N 3.47Å; Q588-R591 VanDerWaalsContact O-N 3.11Å; Y589-R591 VanDerWaalsContact C-N 3.33Å; Y589-R591 PolarHBondContact O-N 2.91Å; R591-M593 VanDerWaalsContact C-N 3.35Å; R591-P595 WeakPolarHBondContact O-CD 3.47Å
592D97.1Very high97.7Very high16 Ų1641.3 Ų41.39%0.08621%0.206CC..Hα-helixtrans-65.7-39.4177.7-66.3-17000111.4L459 Y509 Q588 Y589L459-D592 HydrophobicContact CD2-CB 4.03Å; L459-D592 WeakPolarHBondContact CD2-O 3.33Å; Y509-D592 HydrophobicContact CE1-CB 3.88Å; Y509-D592 WeakPolarHBondContact CE1-OD2 3.1Å; Y509-D592 PolarHBondContact OH-OD2 2.8Å; Q588-D592 PolarHBondContact NE2-OD1 3.26Å; Q588-D592 VanDerWaalsContact O-CG 3.31Å; Q588-D592 PolarHBondContact O-N 2.73Å; Y589-D592 PolarHBondContact O-N 3.25Å
593M98.3Very high97.7Very high0 Ų039.7 Ų39.70%020%0.201CC..Hα-helixtrans-81.5-24-176.8-64.5-66.9156.700113.7Y509 A512 F573 V577 Y589 L590 R591 I596 C597Y509-M593 HydrophobicContact CD1-CE 3.34Å; Y509-M593 HydrophobicContact CD2-CE 4.15Å; Y509-M593 HydrophobicContact CE1-CE 3.62Å; Y509-M593 HydrophobicContact CE2-CE 4.37Å; Y509-M593 HydrophobicContact CG-CE 3.64Å; A512-M593 HydrophobicContact CB-CE 3.88Å; A512-M593 HydrophobicContact CB-SD 3.53Å; A512-M593 VanDerWaalsContact CB-SD 3.53Å; F573-M593 HydrophobicContact CZ-SD 4.06Å; V577-M593 HydrophobicContact CG1-CB 3.5Å; V577-M593 VanDerWaalsContact CG1-CB 3.5Å; V577-M593 HydrophobicContact CG1-CG 4.01Å; V577-M593 HydrophobicContact CG2-CB 4.17Å; V577-M593 HydrophobicContact CG2-CG 4.2Å; V577-M593 HydrophobicContact CG2-SD 4.25Å; Y589-M593 HydrophobicContact CD1-CG 4.38Å; Y589-M593 HydrophobicContact CD2-CE 3.85Å; Y589-M593 HydrophobicContact CD2-CG 3.92Å; Y589-M593 HydrophobicContact CE1-CG 4.07Å; Y589-M593 HydrophobicContact CE2-CE 3.38Å; Y589-M593 HydrophobicContact CE2-CG 3.58Å; Y589-M593 HydrophobicContact CE2-SD 4.04Å; Y589-M593 HydrophobicContact CG-CG 4.31Å; Y589-M593 WeakPolarHBondContact O-CB 3.11Å; Y589-M593 WeakPolarHBondContact O-CG 3.47Å; Y589-M593 PolarHBondContact O-N 3.18Å; L590-M593 PolarHBondContact O-N 3.3Å; R591-M593 VanDerWaalsContact C-N 3.35Å; M593-I596 WeakPolarHBondContact O-CB 3.48Å; M593-I596 PolarHBondContact O-N 3.02Å; M593-C597 PolarHBondContact O-N 3.47Å; M593-C597 PolarHBondContact O-SG 3.31Å
594W98.1Very high97.7Very high27 Ų2736.9 Ų36.910%0.10219%0.186CC..Hα-helixtrans-51.3-54.5-177.3173-110.1000114.2L590 I596 C597 Q598 M648 M651 A652 V655 A660 Y664L590-W594 WeakPolarHBondContact O-CB 3.39Å; L590-W594 PolarHBondContact O-N 2.98Å; W594-I596 VanDerWaalsContact C-N 3.26Å; W594-I596 PolarHBondContact O-N 2.86Å; W594-C597 WeakPolarHBondContact O-CB 3.49Å; W594-C597 PolarHBondContact O-N 3.24Å; W594-Q598 HydrophobicContact CD2-CG 4.25Å; W594-Q598 HydrophobicContact CH2-CG 4.18Å; W594-Q598 HydrophobicContact CZ2-CG 3.81Å; W594-Q598 WeakPolarHBondContact O-CG 3.18Å; W594-Q598 PolarHBondContact O-N 3.13Å; W594-M648 HydrophobicContact CE3-CE 4.29Å; W594-M648 HydrophobicContact CH2-CE 3.8Å; W594-M648 HydrophobicContact CZ3-CE 3.51Å; W594-M648 HydrophobicContact CZ3-SD 4.26Å; W594-M651 HydrophobicContact CE3-CB 3.78Å; W594-M651 HydrophobicContact CE3-CE 4.49Å; W594-M651 HydrophobicContact CZ3-CB 3.57Å; W594-M651 HydrophobicContact CZ3-CE 4.36Å; W594-A652 HydrophobicContact CH2-CB 3.75Å; W594-A652 HydrophobicContact CZ2-CB 4.4Å; W594-A652 HydrophobicContact CZ3-CB 4.45Å; W594-V655 HydrophobicContact CB-CG1 4.5Å; W594-V655 HydrophobicContact CD2-CG2 3.75Å; W594-V655 HydrophobicContact CE3-CG2 4.28Å; W594-V655 HydrophobicContact CG-CG1 4.34Å; W594-V655 HydrophobicContact CG-CG2 4.08Å; W594-V655 HydrophobicContact CZ2-CG2 4Å; W594-A660 HydrophobicContact CH2-CB 4.11Å; W594-A660 HydrophobicContact CZ2-CB 3.9Å; W594-Y664 HydrophobicContact CH2-CE2 4.26Å
595P97.7Very high97.6Very high32 Ų3236.4 Ų36.421%0.20818%0.182CC..Hα-helixtrans-65.6-30.9-17927.6-36.4000112.6G457 R591 Q598 A599G457-P595 WeakPolarHBondContact O-CB 3.06Å; G457-P595 WeakPolarHBondContact O-CG 3.04Å; R591-P595 WeakPolarHBondContact O-CD 3.47Å; P595-Q598 PolarHBondContact O-N 3.29Å; P595-A599 PolarHBondContact O-N 3.33Å
596I98.4Very high97.6Very high1 Ų135.9 Ų35.91%0.00518%0.178CC..Hα-helixtrans-67.8-42.7175-49.2-58.9000110.6L459 A512 V515 V516 F573 M593 W594 Q598 A599 V600L459-I596 HydrophobicContact CD2-CG1 4.33Å; A512-I596 HydrophobicContact CB-CG1 4.38Å; A512-I596 HydrophobicContact CB-CG2 4.17Å; V515-I596 HydrophobicContact CB-CG2 3.87Å; V515-I596 HydrophobicContact CG1-CG2 3.79Å; V515-I596 HydrophobicContact CG2-CG2 4.09Å; V516-I596 HydrophobicContact CG1-CD1 3.64Å; F573-I596 HydrophobicContact CE1-CB 4.29Å; F573-I596 HydrophobicContact CE1-CG2 3.75Å; F573-I596 HydrophobicContact CZ-CB 4.37Å; F573-I596 HydrophobicContact CZ-CG2 3.76Å; M593-I596 WeakPolarHBondContact O-CB 3.48Å; M593-I596 PolarHBondContact O-N 3.02Å; W594-I596 VanDerWaalsContact C-N 3.26Å; W594-I596 PolarHBondContact O-N 2.86Å; I596-Q598 VanDerWaalsContact C-N 3.31Å; I596-Q598 PolarHBondContact O-N 3.04Å; I596-A599 WeakPolarHBondContact O-CB 3.28Å; I596-A599 PolarHBondContact O-N 3.11Å; I596-V600 PolarHBondContact O-N 3.17Å
597C98.8Very high97.6Very high0 Ų034.5 Ų34.50%017%0.17CC..Hα-helixtrans-60.2-41.1174.1-67.80000111.5V574 M593 W594 V600 M601 M648 M651V574-C597 HydrophobicContact CG2-CB 4.17Å; M593-C597 PolarHBondContact O-N 3.47Å; M593-C597 PolarHBondContact O-SG 3.31Å; W594-C597 WeakPolarHBondContact O-CB 3.49Å; W594-C597 PolarHBondContact O-N 3.24Å; C597-V600 VanDerWaalsContact O-CG2 3.27Å; C597-V600 WeakPolarHBondContact O-CG2 3.1Å; C597-M601 WeakPolarHBondContact O-CB 3.23Å; C597-M601 WeakPolarHBondContact O-CG 3.44Å; C597-M601 PolarHBondContact O-N 3.04Å; C597-M601 VanDerWaalsContact O-N 3.07Å; C597-M648 HydrophobicContact CB-CE 4.2Å; C597-M648 HydrophobicContact CB-SD 3.87Å; C597-M651 HydrophobicContact CB-CE 4.24Å
598Q98.4Very high97.7Very high65 Ų6532.7 Ų32.730%0.30416%0.156SC..Hα-helixtrans-62.6-43.4174.3-66.4-173.4-87.600111.8W594 P595 I596 V600 M601 E602 M648W594-Q598 HydrophobicContact CD2-CG 4.25Å; W594-Q598 HydrophobicContact CH2-CG 4.18Å; W594-Q598 HydrophobicContact CZ2-CG 3.81Å; W594-Q598 WeakPolarHBondContact O-CG 3.18Å; W594-Q598 PolarHBondContact O-N 3.13Å; P595-Q598 PolarHBondContact O-N 3.29Å; I596-Q598 VanDerWaalsContact C-N 3.31Å; I596-Q598 PolarHBondContact O-N 3.04Å; Q598-V600 PolarHBondContact O-N 3.48Å; Q598-M601 PolarHBondContact O-N 3.4Å; Q598-E602 WeakPolarHBondContact O-CB 3.25Å; Q598-E602 PolarHBondContact O-N 3.15Å; Q598-M648 HydrophobicContact CG-CE 4.03Å
599A97.6Very high97.7Very high22 Ų2235.2 Ų35.218%0.18217%0.167CC..Hα-helixtrans-61.9-43.8-179.200000112.8N538 P595 I596 S603N538-A599 HydrophobicContact CB-CB 4.39Å; P595-A599 PolarHBondContact O-N 3.33Å; I596-A599 WeakPolarHBondContact O-CB 3.28Å; I596-A599 PolarHBondContact O-N 3.11Å; A599-S603 PolarHBondContact O-N 3.07Å
600V98.3Very high97.6Very high0 Ų040.5 Ų40.50%020%0.195CC..Hα-helixtrans-69.9-41.1177.8-59.10000111.5V515 V540 N570 F573 V574 I596 C597 Q598 E602 S603 E604V515-V600 HydrophobicContact CG1-CG1 3.45Å; V515-V600 VanDerWaalsContact CG1-CG1 3.45Å; V515-V600 HydrophobicContact CG2-CG1 4.21Å; V540-V600 HydrophobicContact CG2-CG1 4.16Å; N570-V600 HydrophobicContact CB-CB 3.92Å; N570-V600 HydrophobicContact CB-CG2 4.44Å; F573-V600 HydrophobicContact CD1-CG2 4.14Å; V574-V600 HydrophobicContact CG2-CG2 3.48Å; V574-V600 VanDerWaalsContact CG2-CG2 3.48Å; I596-V600 PolarHBondContact O-N 3.17Å; C597-V600 VanDerWaalsContact O-CG2 3.27Å; C597-V600 WeakPolarHBondContact O-CG2 3.1Å; Q598-V600 PolarHBondContact O-N 3.48Å; V600-E602 VanDerWaalsContact C-N 3.32Å; V600-E602 PolarHBondContact O-N 3.49Å; V600-S603 WeakPolarHBondContact O-CB 3.43Å; V600-S603 PolarHBondContact O-N 3.29Å; V600-S603 VanDerWaalsContact O-N 3.09Å; V600-S603 PolarHBondContact O-OG 2.99Å; V600-E604 WeakPolarHBondContact O-CG 3.45Å; V600-E604 PolarHBondContact O-N 3.2Å; V600-E604 VanDerWaalsContact O-N 3.12Å
601M98.4Very high97.6Very high1 Ų142.2 Ų42.21%0.00522%0.215CC..Hα-helixtrans-63.8-37.4177-71.1-62.6-62.100112.2L571 V574 C597 Q598 S603 E604 L605 W641 L645 M648 Y664L571-M601 HydrophobicContact CD2-SD 4.15Å; V574-M601 HydrophobicContact CG1-SD 4.39Å; V574-M601 HydrophobicContact CG2-CG 3.91Å; V574-M601 HydrophobicContact CG2-SD 3.96Å; C597-M601 WeakPolarHBondContact O-CB 3.23Å; C597-M601 WeakPolarHBondContact O-CG 3.44Å; C597-M601 PolarHBondContact O-N 3.04Å; C597-M601 VanDerWaalsContact O-N 3.07Å; Q598-M601 PolarHBondContact O-N 3.4Å; M601-S603 VanDerWaalsContact C-N 3.29Å; M601-S603 PolarHBondContact O-N 2.74Å; M601-E604 PolarHBondContact O-N 3.27Å; M601-L605 PolarHBondContact O-N 3.02Å; M601-W641 HydrophobicContact CE-CE3 3.94Å; M601-W641 HydrophobicContact CE-CH2 3.81Å; M601-W641 HydrophobicContact CE-CZ3 3.36Å; M601-W641 HydrophobicContact SD-CZ3 4.27Å; M601-L645 HydrophobicContact CE-CD2 3.72Å; M601-L645 HydrophobicContact CE-CG 4.17Å; M601-M648 HydrophobicContact CE-CG 4.18Å; M601-M648 HydrophobicContact CG-CE 4.15Å; M601-M648 HydrophobicContact CG-CG 3.81Å; M601-M648 HydrophobicContact CG-SD 3.89Å; M601-M648 HydrophobicContact SD-CG 4.22Å; M601-Y664 HydrophobicContact CB-CE1 4.23Å
602E97.5Very high97.6Very high93 Ų9337.7 Ų37.744%0.43520%0.201SC..Hα-helixtrans-62.6-39173.6-168.667.9-141.700111.4Q598 V600 E604 L605 R663Q598-E602 WeakPolarHBondContact O-CB 3.25Å; Q598-E602 PolarHBondContact O-N 3.15Å; V600-E602 VanDerWaalsContact C-N 3.32Å; V600-E602 PolarHBondContact O-N 3.49Å; E602-E604 VanDerWaalsContact C-N 3.31Å; E602-E604 PolarHBondContact O-N 3.12Å; E602-L605 PolarHBondContact O-N 3.15Å; E602-R663 VanDerWaalsContact CD-NH2 3.27Å; E602-R663 IonicContact OE1-NH2 3.47Å; E602-R663 PolarHBondContact OE1-NH2 2.89Å; E602-R663 IonicContact OE2-CZ 3.72Å; E602-R663 IonicContact OE2-NH1 3.79Å; E602-R663 PolarHBondContact OE2-NH1 3.37Å; E602-R663 IonicContact OE2-NH2 2.57Å; E602-R663 PolarHBondContact OE2-NH2 3.04Å
603S96.8Very high97.6Very high22 Ų2237 Ų3715%0.15420%0.197CC..Hα-helixtrans-67.3-31.7178.980.50000113.1N538 N570 A599 V600 M601 L605 K606N538-S603 PolarHBondContact O-OG 3.26Å; N570-S603 PolarHBondContact ND2-OG 3.32Å; A599-S603 PolarHBondContact O-N 3.07Å; V600-S603 WeakPolarHBondContact O-CB 3.43Å; V600-S603 PolarHBondContact O-N 3.29Å; V600-S603 VanDerWaalsContact O-N 3.09Å; V600-S603 PolarHBondContact O-OG 2.99Å; M601-S603 VanDerWaalsContact C-N 3.29Å; M601-S603 PolarHBondContact O-N 2.74Å; S603-L605 VanDerWaalsContact C-N 3.35Å; S603-K606 VanDerWaalsContact O-CD 3.27Å; S603-K606 WeakPolarHBondContact O-CD 3.28Å; S603-K606 WeakPolarHBondContact O-CG 3.4Å
604E97.4Very high97.6Very high1 Ų137 Ų371%0.00520%0.197CC..Hα-helixtrans-73.4-23.8178.9-70-60.1129.100113.1N570 L571 V600 M601 E602 K606 F607 W641N570-E604 HydrophobicContact CB-CG 3.76Å; N570-E604 VanDerWaalsContact CB-OE1 3.31Å; N570-E604 WeakPolarHBondContact CB-OE1 3.24Å; N570-E604 PolarHBondContact ND2-OE1 2.91Å; L571-E604 HydrophobicContact CD2-CG 4Å; V600-E604 WeakPolarHBondContact O-CG 3.45Å; V600-E604 PolarHBondContact O-N 3.2Å; V600-E604 VanDerWaalsContact O-N 3.12Å; M601-E604 PolarHBondContact O-N 3.27Å; E602-E604 VanDerWaalsContact C-N 3.31Å; E602-E604 PolarHBondContact O-N 3.12Å; E604-K606 PolarHBondContact O-N 3.01Å; E604-K606 VanDerWaalsContact O-N 3.07Å; E604-F607 WeakPolarHBondContact O-CB 3.4Å; E604-F607 WeakPolarHBondContact O-CD2 3.39Å; E604-F607 PolarHBondContact O-N 2.85Å; E604-F607 VanDerWaalsContact OE2-CD2 3.23Å; E604-F607 WeakPolarHBondContact OE2-CD2 3.2Å; E604-F607 WeakPolarHBondContact OE2-CE2 3.35Å; E604-W641 HydrophobicContact CB-CE3 4.35Å; E604-W641 HydrophobicContact CB-CZ3 3.73Å
605L96.9Very high97.7Very high35 Ų3535.7 Ų35.718%0.18319%0.192CC..G310 helixtrans-60.7-21.2178.7-71.4172000113.4M601 E602 S603 F607 D608 W641 L667M601-L605 PolarHBondContact O-N 3.02Å; E602-L605 PolarHBondContact O-N 3.15Å; S603-L605 VanDerWaalsContact C-N 3.35Å; L605-F607 PolarHBondContact O-N 2.65Å; L605-F607 VanDerWaalsContact O-N 3.14Å; L605-D608 PolarHBondContact O-N 3.48Å; L605-W641 HydrophobicContact CD2-CH2 3.71Å; L605-W641 HydrophobicContact CD2-CZ2 4.04Å; L605-W641 HydrophobicContact CG-CH2 4.35Å; L605-L667 HydrophobicContact CD2-CD1 3.85Å; L605-L667 HydrophobicContact CD2-CD2 3.95Å
606K96.4Very high97.7Very high104 Ų10435 Ų3545%0.45219%0.186SC..G310 helixtrans-62.7-17174.579.9-169.7-178.21730112.8D565 S603 E604D565-K606 IonicContact OD1-NZ 3.94Å; D565-K606 PolarHBondContact OD1-NZ 3.34Å; S603-K606 VanDerWaalsContact O-CD 3.27Å; S603-K606 WeakPolarHBondContact O-CD 3.28Å; S603-K606 WeakPolarHBondContact O-CG 3.4Å; E604-K606 PolarHBondContact O-N 3.01Å; E604-K606 VanDerWaalsContact O-N 3.07Å
607F98.1Very high97.7Very high13 Ų1335.1 Ų35.16%0.05719%0.187CC..G310 helixtrans-97.12.3-179.3-54.7-54.5000114D565 K567 E604 L605 I615 E616D565-F607 HydrophobicContact CB-CE1 4.32Å; D565-F607 HydrophobicContact CB-CZ 4.17Å; K567-F607 HydrophobicContact CD-CB 4.15Å; K567-F607 HydrophobicContact CD-CD1 3.99Å; K567-F607 HydrophobicContact CD-CD2 3.43Å; K567-F607 VanDerWaalsContact CD-CD2 3.43Å; K567-F607 HydrophobicContact CD-CE1 4.11Å; K567-F607 HydrophobicContact CD-CE2 3.6Å; K567-F607 HydrophobicContact CD-CG 3.62Å; K567-F607 HydrophobicContact CD-CZ 3.92Å; E604-F607 WeakPolarHBondContact O-CB 3.4Å; E604-F607 WeakPolarHBondContact O-CD2 3.39Å; E604-F607 PolarHBondContact O-N 2.85Å; E604-F607 VanDerWaalsContact OE2-CD2 3.23Å; E604-F607 WeakPolarHBondContact OE2-CD2 3.2Å; E604-F607 WeakPolarHBondContact OE2-CE2 3.35Å; L605-F607 PolarHBondContact O-N 2.65Å; L605-F607 VanDerWaalsContact O-N 3.14Å; F607-I615 HydrophobicContact CB-CB 3.96Å; F607-I615 HydrophobicContact CB-CG2 4.05Å; F607-I615 CarbonylContact O-C 3.53Å; F607-I615 VanDerWaalsContact O-CA 3.24Å; F607-I615 WeakPolarHBondContact O-CA 3.44Å; F607-E616 PolarHBondContact O-N 2.93Å
608D97.9Very high97.5Very high25 Ų2537.7 Ų37.713%0.13421%0.205CC..  trans-9191163.5173.57.3000106.8L605 G611 D612 G613L605-D608 PolarHBondContact O-N 3.48Å; D608-G611 WeakPolarHBondContact OD1-CA 3.12Å; D608-G611 PolarHBondContact OD1-N 3.2Å; D608-D612 PolarHBondContact OD1-N 3.32Å; D608-G613 PolarHBondContact OD1-N 2.84Å; D608-G613 WeakPolarHBondContact OD2-CA 3.41Å; D608-G613 PolarHBondContact OD2-N 3.28Å
609Q97Very high97.2Very high141 Ų14136 Ų3666%0.65921%0.205SC*.SBendtrans-83.2-22.7-169.8-72168.273.500113.2E616Q609-E616 WeakPolarHBondContact CB-OE2 3.29Å; Q609-E616 WeakPolarHBondContact CG-OE2 3.42Å; Q609-E616 PolarHBondContact N-OE1 3.11Å; Q609-E616 PolarHBondContact N-OE2 2.93Å; Q609-E616 PolarHBondContact NE2-OE2 3.37Å
610D96.6Very high96.9Very high111 Ų11138.8 Ų38.859%0.59421%0.212SC*.SBendtrans-108.2-4.1-179.373.99.3000114.2D612D610-D612 VanDerWaalsContact C-N 3.32Å; D610-D612 VanDerWaalsContact OD1-CB 3.25Å; D610-D612 WeakPolarHBondContact OD1-CB 3.39Å; D610-D612 PolarHBondContact OD1-N 2.94Å
611G97Very high96.6Very high44 Ų4439 Ų3945%0.45421%0.214SC..SBendtrans76.817.3175.500000113.3D608 G613 R670D608-G611 WeakPolarHBondContact OD1-CA 3.12Å; D608-G611 PolarHBondContact OD1-N 3.2Å; G611-G613 PolarHBondContact O-N 3.45Å; G611-R670 PolarHBondContact O-NH1 3.01Å
612D97.5Very high96.5Very high39 Ų3939 Ų3921%0.20921%0.214CC..SBendtrans-80.3-3176.883.53.2000113.4D608 D610 L614 R670 G671 A674D608-D612 PolarHBondContact OD1-N 3.32Å; D610-D612 VanDerWaalsContact C-N 3.32Å; D610-D612 VanDerWaalsContact OD1-CB 3.25Å; D610-D612 WeakPolarHBondContact OD1-CB 3.39Å; D610-D612 PolarHBondContact OD1-N 2.94Å; D612-L614 VanDerWaalsContact OD1-CB 3.24Å; D612-L614 WeakPolarHBondContact OD1-CB 3.07Å; D612-L614 PolarHBondContact OD1-N 3.41Å; D612-R670 CarbonylContact O-C 3.28Å; D612-R670 WeakPolarHBondContact O-CB 3.34Å; D612-G671 PolarHBondContact O-N 3.47Å; D612-A674 HydrophobicContact CB-CB 4.25Å; D612-A674 WeakPolarHBondContact OD2-CB 3.4Å
613G97.4Very high96.5Very high0 Ų034.6 Ų34.60%019%0.193CC..SBendtrans88.57.7177.600000113.9D608 G611 W641 R670 G671D608-G613 PolarHBondContact OD1-N 2.84Å; D608-G613 WeakPolarHBondContact OD2-CA 3.41Å; D608-G613 PolarHBondContact OD2-N 3.28Å; G611-G613 PolarHBondContact O-N 3.45Å; G613-W641 PolarHBondContact O-NE1 3.42Å; G613-R670 VanDerWaalsContact N-NH1 3.14Å; G613-G671 WeakPolarHBondContact O-CA 3.41Å
614L98.2Very high96.5Very high0 Ų033.8 Ų33.80%019%0.187CC..  trans-120.3137.1177.6-173.160.5000110.9D612 P633 L642 A674 F675 L678D612-L614 VanDerWaalsContact OD1-CB 3.24Å; D612-L614 WeakPolarHBondContact OD1-CB 3.07Å; D612-L614 PolarHBondContact OD1-N 3.41Å; L614-P633 HydrophobicContact CD2-CB 3.56Å; L614-P633 HydrophobicContact CD2-CG 3.88Å; L614-P633 HydrophobicContact CG-CB 4.07Å; L614-P633 HydrophobicContact CG-CG 4.19Å; L614-L642 HydrophobicContact CD1-CD2 4.48Å; L614-A674 HydrophobicContact CB-CB 4.01Å; L614-A674 HydrophobicContact CD2-CB 4.04Å; L614-F675 HydrophobicContact CD1-CB 4.37Å; L614-F675 HydrophobicContact CD1-CD2 4.17Å; L614-F675 HydrophobicContact CD2-CB 3.92Å; L614-F675 HydrophobicContact CD2-CD2 4.27Å; L614-L678 HydrophobicContact CD2-CD1 4.4Å
615I98.4Very high96.5Very high0 Ų033.7 Ų33.70%019%0.187CC..  trans-79.7149.8179.763.5171.3000112.6K567 L571 F607 W641K567-I615 HydrophobicContact CB-CD1 4.18Å; L571-I615 HydrophobicContact CD1-CD1 3.86Å; F607-I615 HydrophobicContact CB-CB 3.96Å; F607-I615 HydrophobicContact CB-CG2 4.05Å; F607-I615 CarbonylContact O-C 3.53Å; F607-I615 VanDerWaalsContact O-CA 3.24Å; F607-I615 WeakPolarHBondContact O-CA 3.44Å; I615-W641 HydrophobicContact CD1-CB 3.82Å; I615-W641 HydrophobicContact CD1-CG 4.28Å; I615-W641 HydrophobicContact CG1-CB 3.86Å; I615-W641 HydrophobicContact CG1-CD2 4.46Å; I615-W641 HydrophobicContact CG1-CG 4.03Å; I615-W641 HydrophobicContact CG2-CD2 3.77Å; I615-W641 HydrophobicContact CG2-CE3 3.93Å; I615-W641 HydrophobicContact CG2-CG 4.14Å; I615-W641 HydrophobicContact CG2-CZ2 4.38Å; I615-W641 HydrophobicContact CG2-CZ3 4.32Å
616E98.4Very high96.3Very high17 Ų1734 Ų348%0.07919%0.188CC..  trans-113.5135.6175.9-44.693.4-177.800114.3K567 F607 Q609 P633K567-E616 WeakPolarHBondContact CE-O 3.49Å; F607-E616 PolarHBondContact O-N 2.93Å; Q609-E616 WeakPolarHBondContact CB-OE2 3.29Å; Q609-E616 WeakPolarHBondContact CG-OE2 3.42Å; Q609-E616 PolarHBondContact N-OE1 3.11Å; Q609-E616 PolarHBondContact N-OE2 2.93Å; Q609-E616 PolarHBondContact NE2-OE2 3.37Å; E616-P633 HydrophobicContact CG-CG 3.92Å
617N98.1Very high96Very high4 Ų430.6 Ų30.62%0.02118%0.183CC..EExtended strand (participates in β ladder)trans-72.1146.1167.5-66.995.5000111.4K567 G619 D622 V630 G632 S634 C637K567-N617 WeakPolarHBondContact CG-ND2 3.44Å; N617-G619 PolarHBondContact O-N 3.25Å; N617-D622 PolarHBondContact ND2-OD1 3.39Å; N617-V630 HydrophobicContact CB-CB 3.68Å; N617-V630 HydrophobicContact CB-CG1 3.55Å; N617-V630 VanDerWaalsContact CG-CG1 3.5Å; N617-V630 WeakPolarHBondContact OD1-CG1 3.15Å; N617-G632 WeakPolarHBondContact CB-O 3.33Å; N617-G632 PolarHBondContact N-O 3.17Å; N617-G632 PolarHBondContact O-N 3.08Å; N617-S634 WeakPolarHBondContact OD1-CB 3.26Å; N617-S634 PolarHBondContact OD1-OG 2.74Å; N617-C637 PolarHBondContact ND2-SG 3.43Å
618S95.7Very high95.8Very high55 Ų5530.3 Ų30.339%0.38518%0.182SC..EExtended strand (participates in β ladder)trans-91.911-161.8-56.80000115.3K567 D622K567-S618 PolarHBondContact NZ-OG 3.23Å; K567-S618 VanDerWaalsContact NZ-OG 3.08Å; S618-D622 PolarHBondContact N-OD2 3.14Å
619G92.3Very high95.7Very high30 Ų3032.1 Ų32.131%0.30919%0.194SC..SBendtrans82.817.5178.600000115.2N617 T629 V630 T631N617-G619 PolarHBondContact O-N 3.25Å; G619-T629 WeakPolarHBondContact O-CG2 3.43Å; G619-V630 WeakPolarHBondContact CA-O 3.12Å; G619-V630 PolarHBondContact N-O 3.3Å; G619-T631 VanDerWaalsContact CA-OG1 3.32Å; G619-T631 WeakPolarHBondContact CA-OG1 3.48Å
620Y91.3Very high95.6Very high80 Ų8025.6 Ų25.631%0.31416%0.163SC..SBendtrans-138.217816763.5-86.8000108.6D565 D622D565-Y620 WeakPolarHBondContact CB-OH 3.27Å; Y620-D622 HydrophobicContact CD2-CB 4.05Å; Y620-D622 HydrophobicContact CE2-CB 3.58Å; Y620-D622 PolarHBondContact O-N 3.13Å
621A92.1Very high95.6Very high5 Ų521.8 Ų21.84%0.04114%0.144CC..  trans-76.9101.4174.600000110.2H561 D626H561-A621 PolarHBondContact ND1-O 3.32Å; H561-A621 VanDerWaalsContact ND1-O 3.15Å; A621-D626 WeakPolarHBondContact CB-O 3.49Å
622D96.2Very high95.6Very high0 Ų020.3 Ų20.30%013%0.129CC..  trans-120.840.8-176.860-7.2000111.8W566 K567 N617 S618 Y620W566-D622 CarbonylContact C-O 3.6Å; W566-D622 WeakPolarHBondContact CA-O 3.42Å; K567-D622 PolarHBondContact N-O 3.44Å; K567-D622 IonicContact NZ-OD2 2.74Å; K567-D622 PolarHBondContact NZ-OD2 3.36Å; N617-D622 PolarHBondContact ND2-OD1 3.39Å; S618-D622 PolarHBondContact N-OD2 3.14Å; Y620-D622 HydrophobicContact CD2-CB 4.05Å; Y620-D622 HydrophobicContact CE2-CB 3.58Å; Y620-D622 PolarHBondContact O-N 3.13Å
623Q97Very high95.6Very high1 Ų119 Ų191%0.00512%0.123CC..SBendtrans-167.3176.9179.546.166.242.900110.3D568 Y625 D626 W628 V630 Y636D568-Q623 HydrophobicContact CB-CB 4.16Å; D568-Q623 WeakPolarHBondContact OD1-CA 3.25Å; Q623-Y625 VanDerWaalsContact C-N 3.25Å; Q623-Y625 PolarHBondContact NE2-O 3.17Å; Q623-Y625 CarbonylContact O-C 3.48Å; Q623-Y625 PolarHBondContact O-N 3.37Å; Q623-Y625 VanDerWaalsContact OE1-CB 3.29Å; Q623-Y625 VanDerWaalsContact OE1-CD2 3.22Å; Q623-D626 PolarHBondContact O-N 2.8Å; Q623-W628 PolarHBondContact NE2-O 3.45Å; Q623-V630 HydrophobicContact CG-CG2 4.49Å; Q623-Y636 HydrophobicContact CB-CE1 4.25Å; Q623-Y636 HydrophobicContact CG-CD1 4.48Å; Q623-Y636 HydrophobicContact CG-CE1 4.49Å
624T97.4Very high95.7Very high4 Ų419 Ų193%0.02512%0.123CC..SBendtrans-48.6-33.5-174.5-161.30000116.3D487 D568 D626 Y636 W770 R828D487-T624 WeakPolarHBondContact OD2-CB 3.46Å; D487-T624 PolarHBondContact OD2-OG1 3.37Å; D568-T624 WeakPolarHBondContact OD2-CB 3.26Å; D568-T624 PolarHBondContact OD2-N 2.84Å; T624-D626 PolarHBondContact O-N 3.22Å; T624-Y636 HydrophobicContact CG2-CE1 4.05Å; T624-Y636 WeakPolarHBondContact CG2-OH 3.49Å; T624-W770 HydrophobicContact CG2-CZ3 4.23Å; T624-R828 PolarHBondContact OG1-NH1 3.49Å; T624-R828 PolarHBondContact OG1-NH2 2.6Å
625Y96.9Very high95.7Very high0 Ų019.1 Ų19.10%012%0.124CC..SBendtrans-7766.1168.3-56.9-99.7000109Q623 G627 W628 Y636 M699 D701 N751 Q765 W770 V773Q623-Y625 VanDerWaalsContact C-N 3.25Å; Q623-Y625 PolarHBondContact NE2-O 3.17Å; Q623-Y625 CarbonylContact O-C 3.48Å; Q623-Y625 PolarHBondContact O-N 3.37Å; Q623-Y625 VanDerWaalsContact OE1-CB 3.29Å; Q623-Y625 VanDerWaalsContact OE1-CD2 3.22Å; Y625-G627 PolarHBondContact O-N 3.06Å; Y625-W628 HydrophobicContact CD1-CE3 4.09Å; Y625-W628 HydrophobicContact CG-CE3 4.44Å; Y625-W628 PolarHBondContact O-N 3.43Å; Y625-Y636 HydrophobicContact CD2-CE1 4.32Å; Y625-Y636 HydrophobicContact CE2-CE1 4.35Å; Y625-Y636 HydrophobicContact CE2-CE2 4.27Å; Y625-M699 HydrophobicContact CD1-CE 4.35Å; Y625-M699 HydrophobicContact CD2-CE 3.54Å; Y625-M699 HydrophobicContact CE1-CE 4.02Å; Y625-M699 HydrophobicContact CE2-CE 3.18Å; Y625-M699 HydrophobicContact CG-CE 4.14Å; Y625-M699 VanDerWaalsContact CZ-CE 3.45Å; Y625-D701 VanDerWaalsContact OH-CB 3.26Å; Y625-D701 WeakPolarHBondContact OH-CB 3.43Å; Y625-D701 PolarHBondContact OH-OD2 2.86Å; Y625-D701 VanDerWaalsContact OH-OD2 3.07Å; Y625-N751 HydrophobicContact CE1-CB 4.43Å; Y625-Q765 PolarHBondContact O-OE1 3.07Å; Y625-W770 HydrophobicContact CD1-CD2 4.35Å; Y625-W770 AromaticContact CD1-CE3 4Å; Y625-W770 HydrophobicContact CD1-CE3 4Å; Y625-W770 AromaticContact CD1-CH2 3.43Å; Y625-W770 HydrophobicContact CD1-CH2 3.43Å; Y625-W770 VanDerWaalsContact CD1-CH2 3.43Å; Y625-W770 AromaticContact CD1-CZ2 3.79Å; Y625-W770 HydrophobicContact CD1-CZ2 3.79Å; Y625-W770 AromaticContact CD1-CZ3 3.52Å; Y625-W770 HydrophobicContact CD1-CZ3 3.52Å; Y625-W770 HydrophobicContact CD2-CH2 4.49Å; Y625-W770 HydrophobicContact CD2-CZ3 4.2Å; Y625-W770 AromaticContact CE1-CD2 3.94Å; Y625-W770 HydrophobicContact CE1-CD2 3.94Å; Y625-W770 AromaticContact CE1-CE3 3.51Å; Y625-W770 HydrophobicContact CE1-CE3 3.51Å; Y625-W770 AromaticContact CE1-CH2 3.87Å; Y625-W770 HydrophobicContact CE1-CH2 3.87Å; Y625-W770 HydrophobicContact CE1-CZ2 4.22Å; Y625-W770 AromaticContact CE1-CZ3 3.48Å; Y625-W770 HydrophobicContact CE1-CZ3 3.48Å; Y625-W770 VanDerWaalsContact CE1-CZ3 3.48Å; Y625-W770 HydrophobicContact CE2-CZ3 4.15Å; Y625-W770 AromaticContact CG-CH2 3.78Å; Y625-W770 HydrophobicContact CG-CH2 3.78Å; Y625-W770 HydrophobicContact CG-CZ2 4.49Å; Y625-W770 AromaticContact CG-CZ3 3.89Å; Y625-W770 HydrophobicContact CG-CZ3 3.89Å; Y625-W770 AromaticContact CZ-CE3 3.86Å; Y625-W770 AromaticContact CZ-CZ3 3.8Å; Y625-V773 WeakPolarHBondContact OH-CG2 3.27Å
626D91.9Very high95.7Very high40 Ų4019.3 Ų19.321%0.21413%0.125CC..THydrogen-bonded Turntrans-67-2.8-170.175.5-27.2000115.1Y558 H561 W566 A621 Q623 T624 Q765Y558-D626 WeakPolarHBondContact OH-CB 3.48Å; Y558-D626 PolarHBondContact OH-OD2 3.26Å; H561-D626 PolarHBondContact CE1-O 2.82Å; H561-D626 PolarHBondContact NE2-O 3.12Å; W566-D626 HydrophobicContact CH2-CB 3.86Å; W566-D626 HydrophobicContact CZ2-CB 3.87Å; A621-D626 WeakPolarHBondContact CB-O 3.49Å; Q623-D626 PolarHBondContact O-N 2.8Å; T624-D626 PolarHBondContact O-N 3.22Å; D626-Q765 PolarHBondContact OD1-NE2 3.42Å
627G91.6Very high95.7Very high34 Ų3418.5 Ų18.535%0.35112%0.121SC..THydrogen-bonded Turntrans-115.70.8170.900000113.9Y625 S763 Q765Y625-G627 PolarHBondContact O-N 3.06Å; G627-S763 VanDerWaalsContact C-OG 3.28Å; G627-S763 WeakPolarHBondContact O-CB 3.28Å; G627-S763 PolarHBondContact O-OG 2.99Å; G627-Q765 VanDerWaalsContact CA-OE1 3.29Å; G627-Q765 VanDerWaalsContact N-CD 3.32Å
628W93.9Very high95.7Very high7 Ų718.3 Ų18.33%0.02712%0.12CC..SBendtrans-114.5105.4-179.9-159.58.4000110.9Q623 Y625 Y687 M699 N751 S762 Q765Q623-W628 PolarHBondContact NE2-O 3.45Å; Y625-W628 HydrophobicContact CD1-CE3 4.09Å; Y625-W628 HydrophobicContact CG-CE3 4.44Å; Y625-W628 PolarHBondContact O-N 3.43Å; W628-Y687 AromaticContact CD1-CZ 3.95Å; W628-Y687 VanDerWaalsContact CD1-OH 3.29Å; W628-Y687 AromaticContact CD2-CE2 3.75Å; W628-Y687 HydrophobicContact CD2-CE2 3.75Å; W628-Y687 AromaticContact CD2-CZ 3.73Å; W628-Y687 AromaticContact CE2-CE2 3.62Å; W628-Y687 AromaticContact CE2-CZ 3.55Å; W628-Y687 AromaticContact CE3-CE2 3.9Å; W628-Y687 HydrophobicContact CE3-CE2 3.9Å; W628-Y687 HydrophobicContact CG-CE2 4.45Å; W628-Y687 AromaticContact CG-CZ 3.99Å; W628-Y687 AromaticContact CH2-CD2 3.99Å; W628-Y687 HydrophobicContact CH2-CD2 3.99Å; W628-Y687 AromaticContact CH2-CE2 3.82Å; W628-Y687 HydrophobicContact CH2-CE2 3.82Å; W628-Y687 AromaticContact CZ2-CD2 3.92Å; W628-Y687 HydrophobicContact CZ2-CD2 3.92Å; W628-Y687 AromaticContact CZ2-CE2 3.67Å; W628-Y687 HydrophobicContact CZ2-CE2 3.67Å; W628-Y687 HydrophobicContact CZ2-CG 4.46Å; W628-Y687 HydrophobicContact CZ3-CD2 4.46Å; W628-Y687 AromaticContact CZ3-CE2 3.93Å; W628-Y687 HydrophobicContact CZ3-CE2 3.93Å; W628-Y687 AromaticContact NE1-CZ 3.71Å; W628-Y687 PolarHBondContact O-OH 3.42Å; W628-M699 HydrophobicContact CH2-CB 4.41Å; W628-M699 HydrophobicContact CH2-CG 4.17Å; W628-M699 HydrophobicContact CZ3-CE 4.25Å; W628-M699 HydrophobicContact CZ3-CG 3.95Å; W628-M699 HydrophobicContact CZ3-SD 4.46Å; W628-N751 HydrophobicContact CZ3-CB 4.21Å; W628-S762 PolarHBondContact NE1-OG 3.24Å; W628-Q765 HydrophobicContact CB-CB 4.42Å; W628-Q765 VanDerWaalsContact N-OE1 3.16Å
629T93.9Very high95.8Very high62 Ų6215.8 Ų15.838%0.3810%0.102SC..  trans-67.2140.3-176.2-63.60000112.1G619 Y687G619-T629 WeakPolarHBondContact O-CG2 3.43Å; T629-Y687 VanDerWaalsContact O-CE1 3.3Å; T629-Y687 WeakPolarHBondContact O-CE1 3.12Å; T629-Y687 PolarHBondContact O-OH 3.26Å
630V94.9Very high96.1Very high4 Ų414.4 Ų14.42%0.0249%0.088CC..  trans-128.5140176.6-170.40000108.9N617 G619 Q623 Y687 D688N617-V630 HydrophobicContact CB-CB 3.68Å; N617-V630 HydrophobicContact CB-CG1 3.55Å; N617-V630 VanDerWaalsContact CG-CG1 3.5Å; N617-V630 WeakPolarHBondContact OD1-CG1 3.15Å; G619-V630 WeakPolarHBondContact CA-O 3.12Å; G619-V630 PolarHBondContact N-O 3.3Å; Q623-V630 HydrophobicContact CG-CG2 4.49Å; V630-Y687 HydrophobicContact CG2-CE1 4.22Å; V630-Y687 HydrophobicContact CG2-CE2 4.39Å; V630-Y687 WeakPolarHBondContact CG2-OH 3.42Å; V630-D688 HydrophobicContact CG1-CB 3.9Å
631T96.6Very high96.4Very high31 Ų3110.6 Ų10.619%0.197%0.073CC..EExtended strand (participates in β ladder)trans-133131.1175.3-47.90000111.9G619 D688 R692G619-T631 VanDerWaalsContact CA-OG1 3.32Å; G619-T631 WeakPolarHBondContact CA-OG1 3.48Å; T631-D688 PolarHBondContact N-OD2 2.78Å; T631-D688 WeakPolarHBondContact O-CB 3.47Å; T631-R692 PolarHBondContact OG1-NH1 2.95Å
632G97.7Very high96.7Very high14 Ų1410.3 Ų10.314%0.1447%0.071CC..EExtended strand (participates in β ladder)trans79.7-170.5-176.700000111.7N617N617-G632 WeakPolarHBondContact CB-O 3.33Å; N617-G632 PolarHBondContact N-O 3.17Å; N617-G632 PolarHBondContact O-N 3.08Å
633P97.9Very high96.8Very high10 Ų1010.3 Ų10.37%0.0657%0.071CC..SBendtrans-54140.1168.1-3339.4000112.7L614 E616 L678 D688 S689L614-P633 HydrophobicContact CD2-CB 3.56Å; L614-P633 HydrophobicContact CD2-CG 3.88Å; L614-P633 HydrophobicContact CG-CB 4.07Å; L614-P633 HydrophobicContact CG-CG 4.19Å; E616-P633 HydrophobicContact CG-CG 3.92Å; P633-L678 HydrophobicContact CB-CD1 4.28Å; P633-L678 HydrophobicContact CG-CD1 3.87Å; P633-D688 CarbonylContact O-C 3.49Å; P633-D688 WeakPolarHBondContact O-CA 3.43Å; P633-S689 VanDerWaalsContact CD-OG 3.23Å; P633-S689 WeakPolarHBondContact CD-OG 3.44Å; P633-S689 PolarHBondContact O-N 3.06Å
634S98.3Very high96.9Very high2 Ų210.3 Ų10.31%0.0147%0.071CC..BIsolated β-bridgetrans-130.1153.7-179.567.10000112.3N617 Y636 C637 G638 L679 Y687N617-S634 WeakPolarHBondContact OD1-CB 3.26Å; N617-S634 PolarHBondContact OD1-OG 2.74Å; S634-Y636 VanDerWaalsContact C-N 3.27Å; S634-Y636 PolarHBondContact O-N 3.29Å; S634-C637 WeakPolarHBondContact OG-CB 3.28Å; S634-C637 PolarHBondContact OG-N 3Å; S634-G638 VanDerWaalsContact O-CA 3.24Å; S634-G638 WeakPolarHBondContact O-CA 3.2Å; S634-G638 PolarHBondContact O-N 2.92Å; S634-L679 VanDerWaalsContact C-CD1 3.48Å; S634-Y687 WeakPolarHBondContact CA-O 3.41Å; S634-Y687 WeakPolarHBondContact CB-O 3.24Å
635A98.2Very high96.9Very high1 Ų110.1 Ų10.11%0.0087%0.069CC..Hα-helixtrans-61.2-39.1179.200000111.9G639 N686 Y687 Q702A635-G639 WeakPolarHBondContact O-CA 3.36Å; A635-G639 PolarHBondContact O-N 2.91Å; A635-N686 WeakPolarHBondContact CB-O 3.19Å; A635-Y687 PolarHBondContact N-O 3.2Å; A635-Q702 HydrophobicContact CB-CB 3.8Å
636Y98.6Very high96.9Very high5 Ų510.1 Ų10.12%0.027%0.069CC..Hα-helixtrans-73.2-61.1-178.3178.8-110.3000112.5Y491 D568 K572 Q623 T624 Y625 S634 G639 M640 M699 D701 A704Y491-Y636 PolarHBondContact OH-OH 2.9Å; D568-Y636 HydrophobicContact CB-CE1 4.27Å; D568-Y636 PolarHBondContact OD2-OH 3.32Å; K572-Y636 WeakPolarHBondContact CE-OH 3.27Å; K572-Y636 PolarHBondContact NZ-OH 3.37Å; Q623-Y636 HydrophobicContact CB-CE1 4.25Å; Q623-Y636 HydrophobicContact CG-CD1 4.48Å; Q623-Y636 HydrophobicContact CG-CE1 4.49Å; T624-Y636 HydrophobicContact CG2-CE1 4.05Å; T624-Y636 WeakPolarHBondContact CG2-OH 3.49Å; Y625-Y636 HydrophobicContact CD2-CE1 4.32Å; Y625-Y636 HydrophobicContact CE2-CE1 4.35Å; Y625-Y636 HydrophobicContact CE2-CE2 4.27Å; S634-Y636 VanDerWaalsContact C-N 3.27Å; S634-Y636 PolarHBondContact O-N 3.29Å; Y636-G639 PolarHBondContact O-N 3Å; Y636-M640 HydrophobicContact CD1-CE 3.51Å; Y636-M640 HydrophobicContact CD2-CE 3.87Å; Y636-M640 HydrophobicContact CE1-CE 3.18Å; Y636-M640 HydrophobicContact CE2-CE 3.56Å; Y636-M640 HydrophobicContact CE2-SD 4.12Å; Y636-M640 HydrophobicContact CG-CE 3.83Å; Y636-M640 WeakPolarHBondContact O-CE 3.48Å; Y636-M640 WeakPolarHBondContact O-CG 3.35Å; Y636-M640 PolarHBondContact O-N 3.32Å; Y636-M699 HydrophobicContact CD2-CE 4.3Å; Y636-M699 HydrophobicContact CG-CE 4.08Å; Y636-M699 HydrophobicContact CG-SD 4.48Å; Y636-D701 HydrophobicContact CD2-CB 4.29Å; Y636-D701 WeakPolarHBondContact CE2-OD2 3.19Å; Y636-A704 HydrophobicContact CD2-CB 3.77Å; Y636-A704 HydrophobicContact CE2-CB 3.72Å
637C98.6Very high97.2Very high0 Ų08.2 Ų8.20%06%0.059CC..Hα-helixtrans-72.1-42.5-177.1-58.70000111.8K567 N617 S634 G639 M640 W641K567-C637 HydrophobicContact CB-CB 3.95Å; N617-C637 PolarHBondContact ND2-SG 3.43Å; S634-C637 WeakPolarHBondContact OG-CB 3.28Å; S634-C637 PolarHBondContact OG-N 3Å; C637-G639 VanDerWaalsContact C-N 3.32Å; C637-G639 PolarHBondContact O-N 3.18Å; C637-M640 PolarHBondContact O-N 3.06Å; C637-W641 WeakPolarHBondContact O-CB 3.4Å; C637-W641 PolarHBondContact O-N 3.43Å
638G98.4Very high97.5Very high0 Ų06.6 Ų6.60%04%0.043CC..Hα-helixtrans-61.8-40.2175.200000112.1S634 W641 L642S634-G638 VanDerWaalsContact O-CA 3.24Å; S634-G638 WeakPolarHBondContact O-CA 3.2Å; S634-G638 PolarHBondContact O-N 2.92Å; G638-W641 WeakPolarHBondContact O-CB 3.5Å; G638-W641 PolarHBondContact O-N 2.62Å; G638-L642 WeakPolarHBondContact O-CG 3.31Å; G638-L642 PolarHBondContact O-N 3.08Å
639G97.9Very high97.7Very high2 Ų26.2 Ų6.22%0.0214%0.041CC..Hα-helixtrans-63.9-43.7174.400000112.5A635 Y636 C637 W641 L642 A643 F675 F722A635-G639 WeakPolarHBondContact O-CA 3.36Å; A635-G639 PolarHBondContact O-N 2.91Å; Y636-G639 PolarHBondContact O-N 3Å; C637-G639 VanDerWaalsContact C-N 3.32Å; C637-G639 PolarHBondContact O-N 3.18Å; G639-W641 VanDerWaalsContact C-N 3.29Å; G639-W641 PolarHBondContact O-N 2.95Å; G639-L642 PolarHBondContact O-N 3.29Å; G639-A643 WeakPolarHBondContact O-CB 3.44Å; G639-A643 PolarHBondContact O-N 3.37Å; G639-F675 VanDerWaalsContact N-CE2 3.34Å; G639-F722 WeakPolarHBondContact O-CZ 3.41Å
640M98Very high97.8Very high0 Ų06.9 Ų6.90%04%0.039CC..Hα-helixtrans-64.9-32.9174.8-75.7-173.3-71.300112.7D568 L571 K572 L575 Y636 C637 A643 S644D568-M640 HydrophobicContact CB-CE 3.5Å; D568-M640 HydrophobicContact CB-SD 4.31Å; L571-M640 HydrophobicContact CB-CB 4.21Å; L571-M640 HydrophobicContact CD1-CB 3.98Å; K572-M640 HydrophobicContact CG-SD 4Å; L575-M640 HydrophobicContact CD1-CB 4.4Å; L575-M640 HydrophobicContact CD1-CG 4.32Å; Y636-M640 HydrophobicContact CD1-CE 3.51Å; Y636-M640 HydrophobicContact CD2-CE 3.87Å; Y636-M640 HydrophobicContact CE1-CE 3.18Å; Y636-M640 HydrophobicContact CE2-CE 3.56Å; Y636-M640 HydrophobicContact CE2-SD 4.12Å; Y636-M640 HydrophobicContact CG-CE 3.83Å; Y636-M640 WeakPolarHBondContact O-CE 3.48Å; Y636-M640 WeakPolarHBondContact O-CG 3.35Å; Y636-M640 PolarHBondContact O-N 3.32Å; C637-M640 PolarHBondContact O-N 3.06Å; M640-A643 PolarHBondContact O-N 2.76Å; M640-S644 WeakPolarHBondContact O-CB 3.21Å; M640-S644 PolarHBondContact O-N 3.17Å; M640-S644 PolarHBondContact O-OG 3.5Å
641W98.7Very high97.9Very high0 Ų06.7 Ų6.70%04%0.038CC..Hα-helixtrans-64-50.8176.1167.2-107.5000111.1L571 M601 E604 L605 G613 I615 C637 G638 G639 A643 S644 L645L571-W641 HydrophobicContact CD1-CB 3.95Å; L571-W641 HydrophobicContact CD2-CE3 3.69Å; L571-W641 HydrophobicContact CD2-CZ3 4.29Å; M601-W641 HydrophobicContact CE-CE3 3.94Å; M601-W641 HydrophobicContact CE-CH2 3.81Å; M601-W641 HydrophobicContact CE-CZ3 3.36Å; M601-W641 HydrophobicContact SD-CZ3 4.27Å; E604-W641 HydrophobicContact CB-CE3 4.35Å; E604-W641 HydrophobicContact CB-CZ3 3.73Å; L605-W641 HydrophobicContact CD2-CH2 3.71Å; L605-W641 HydrophobicContact CD2-CZ2 4.04Å; L605-W641 HydrophobicContact CG-CH2 4.35Å; G613-W641 PolarHBondContact O-NE1 3.42Å; I615-W641 HydrophobicContact CD1-CB 3.82Å; I615-W641 HydrophobicContact CD1-CG 4.28Å; I615-W641 HydrophobicContact CG1-CB 3.86Å; I615-W641 HydrophobicContact CG1-CD2 4.46Å; I615-W641 HydrophobicContact CG1-CG 4.03Å; I615-W641 HydrophobicContact CG2-CD2 3.77Å; I615-W641 HydrophobicContact CG2-CE3 3.93Å; I615-W641 HydrophobicContact CG2-CG 4.14Å; I615-W641 HydrophobicContact CG2-CZ2 4.38Å; I615-W641 HydrophobicContact CG2-CZ3 4.32Å; C637-W641 WeakPolarHBondContact O-CB 3.4Å; C637-W641 PolarHBondContact O-N 3.43Å; G638-W641 WeakPolarHBondContact O-CB 3.5Å; G638-W641 PolarHBondContact O-N 2.62Å; G639-W641 VanDerWaalsContact C-N 3.29Å; G639-W641 PolarHBondContact O-N 2.95Å; W641-A643 VanDerWaalsContact C-N 3.3Å; W641-A643 PolarHBondContact O-N 3.5Å; W641-S644 WeakPolarHBondContact O-CB 3.47Å; W641-S644 PolarHBondContact O-N 3.41Å; W641-S644 VanDerWaalsContact O-N 3.11Å; W641-L645 HydrophobicContact CD2-CD1 4.21Å; W641-L645 HydrophobicContact CD2-CG 4.33Å; W641-L645 HydrophobicContact CG-CD1 4.47Å; W641-L645 HydrophobicContact CH2-CD2 4.19Å; W641-L645 HydrophobicContact CZ2-CD1 3.82Å; W641-L645 HydrophobicContact CZ2-CD2 3.98Å; W641-L645 HydrophobicContact CZ2-CG 4.09Å; W641-L645 WeakPolarHBondContact O-CG 3.48Å; W641-L645 PolarHBondContact O-N 2.97Å
642L98.3Very high98Very high0 Ų05.2 Ų5.20%03%0.029CC..Hα-helixtrans-61.5-39.8176.7-61.9-177.1000111.9L614 G638 G639 S644 L645 C646 L668 G671 F675 A721 F722L614-L642 HydrophobicContact CD1-CD2 4.48Å; G638-L642 WeakPolarHBondContact O-CG 3.31Å; G638-L642 PolarHBondContact O-N 3.08Å; G639-L642 PolarHBondContact O-N 3.29Å; L642-S644 VanDerWaalsContact C-N 3.34Å; L642-L645 HydrophobicContact CD2-CD1 4.44Å; L642-L645 PolarHBondContact O-N 2.77Å; L642-C646 PolarHBondContact O-N 3.28Å; L642-C646 PolarHBondContact O-SG 3.3Å; L642-L668 HydrophobicContact CB-CD1 4.3Å; L642-L668 HydrophobicContact CD2-CD1 4.27Å; L642-G671 VanDerWaalsContact CD2-C 3.49Å; L642-F675 HydrophobicContact CD1-CB 3.65Å; L642-F675 HydrophobicContact CD1-CD1 4.08Å; L642-F675 HydrophobicContact CD1-CD2 4.12Å; L642-F675 HydrophobicContact CD1-CG 3.69Å; L642-A721 HydrophobicContact CB-CB 4.17Å; L642-A721 HydrophobicContact CD1-CB 4.37Å; L642-F722 HydrophobicContact CB-CE2 4.38Å; L642-F722 HydrophobicContact CB-CZ 3.94Å
643A98Very high97.9Very high0 Ų010 Ų100%04%0.042CC..Hα-helixtrans-62.9-42174.800000111.8L575 G639 M640 W641 L645 C646 V647 G705 L709 F722L575-A643 HydrophobicContact CD1-CB 4.39Å; L575-A643 HydrophobicContact CD2-CB 3.76Å; G639-A643 WeakPolarHBondContact O-CB 3.44Å; G639-A643 PolarHBondContact O-N 3.37Å; M640-A643 PolarHBondContact O-N 2.76Å; W641-A643 VanDerWaalsContact C-N 3.3Å; W641-A643 PolarHBondContact O-N 3.5Å; A643-L645 PolarHBondContact O-N 3.3Å; A643-C646 WeakPolarHBondContact O-CB 3.48Å; A643-C646 PolarHBondContact O-N 3.26Å; A643-V647 PolarHBondContact O-N 3.08Å; A643-G705 VanDerWaalsContact CB-O 3.32Å; A643-G705 WeakPolarHBondContact CB-O 3.26Å; A643-L709 HydrophobicContact CB-CD1 4.1Å; A643-L709 HydrophobicContact CB-CD2 3.94Å; A643-L709 HydrophobicContact CB-CG 3.77Å; A643-L709 WeakPolarHBondContact O-CD2 3.28Å; A643-F722 HydrophobicContact CB-CE2 4.31Å
644S98.6Very high97.9Very high0 Ų013 Ų130%06%0.058CC..Hα-helixtrans-62.3-43.4176.3-59.60000111.1L571 M640 W641 L642 C646 V647 M648L571-S644 WeakPolarHBondContact CA-OG 3.47Å; L571-S644 WeakPolarHBondContact CB-OG 3.44Å; L571-S644 PolarHBondContact O-OG 3.38Å; M640-S644 WeakPolarHBondContact O-CB 3.21Å; M640-S644 PolarHBondContact O-N 3.17Å; M640-S644 PolarHBondContact O-OG 3.5Å; W641-S644 WeakPolarHBondContact O-CB 3.47Å; W641-S644 PolarHBondContact O-N 3.41Å; W641-S644 VanDerWaalsContact O-N 3.11Å; L642-S644 VanDerWaalsContact C-N 3.34Å; S644-C646 VanDerWaalsContact C-N 3.34Å; S644-C646 PolarHBondContact O-N 2.92Å; S644-V647 WeakPolarHBondContact O-CG2 3.27Å; S644-V647 PolarHBondContact O-N 3.16Å; S644-M648 WeakPolarHBondContact O-CB 3.32Å; S644-M648 VanDerWaalsContact O-CG 3.23Å; S644-M648 WeakPolarHBondContact O-CG 3.21Å; S644-M648 PolarHBondContact O-N 2.94Å
645L98.3Very high97.8Very high0 Ų014.8 Ų14.80%07%0.068CC..Hα-helixtrans-61.7-38.6174-71173.8000112.8M601 W641 L642 A643 M648 C649 Y664 L667 L668M601-L645 HydrophobicContact CE-CD2 3.72Å; M601-L645 HydrophobicContact CE-CG 4.17Å; W641-L645 HydrophobicContact CD2-CD1 4.21Å; W641-L645 HydrophobicContact CD2-CG 4.33Å; W641-L645 HydrophobicContact CG-CD1 4.47Å; W641-L645 HydrophobicContact CH2-CD2 4.19Å; W641-L645 HydrophobicContact CZ2-CD1 3.82Å; W641-L645 HydrophobicContact CZ2-CD2 3.98Å; W641-L645 HydrophobicContact CZ2-CG 4.09Å; W641-L645 WeakPolarHBondContact O-CG 3.48Å; W641-L645 PolarHBondContact O-N 2.97Å; L642-L645 HydrophobicContact CD2-CD1 4.44Å; L642-L645 PolarHBondContact O-N 2.77Å; A643-L645 PolarHBondContact O-N 3.3Å; L645-M648 PolarHBondContact O-N 3.26Å; L645-C649 PolarHBondContact O-N 3.43Å; L645-C649 PolarHBondContact O-SG 3.34Å; L645-Y664 HydrophobicContact CD2-CD1 3.72Å; L645-Y664 HydrophobicContact CD2-CG 4.44Å; L645-L667 HydrophobicContact CD1-CB 3.93Å; L645-L667 HydrophobicContact CD2-CB 3.93Å; L645-L667 HydrophobicContact CD2-CD1 4.21Å; L645-L668 HydrophobicContact CB-CB 4.12Å; L645-L668 HydrophobicContact CB-CD1 3.97Å; L645-L668 HydrophobicContact CD1-CB 4.34Å
646C97.6Very high97.8Very high0 Ų022 Ų220%011%0.107CC..Hα-helixtrans-60.2-49.3174-66.40000111.5L642 A643 S644 C649 K650 L709 Y719L642-C646 PolarHBondContact O-N 3.28Å; L642-C646 PolarHBondContact O-SG 3.3Å; A643-C646 WeakPolarHBondContact O-CB 3.48Å; A643-C646 PolarHBondContact O-N 3.26Å; S644-C646 VanDerWaalsContact C-N 3.34Å; S644-C646 PolarHBondContact O-N 2.92Å; C646-C649 WeakPolarHBondContact O-CB 3.36Å; C646-C649 PolarHBondContact O-N 2.76Å; C646-K650 PolarHBondContact O-N 3.16Å; C646-K650 VanDerWaalsContact O-N 3.08Å; C646-L709 HydrophobicContact CB-CD1 4.25Å; C646-L709 HydrophobicContact CB-CD2 3.84Å; C646-Y719 HydrophobicContact CB-CD2 3.79Å; C646-Y719 HydrophobicContact CB-CE2 4.26Å; C646-Y719 HydrophobicContact CB-CG 3.97Å; C646-Y719 WeakPolarHBondContact SG-CB 3.21Å
647V97Very high97.7Very high0 Ų023.3 Ų23.30%012%0.117CC..Hα-helixtrans-68.8-34.8179.2-57.90000111.6V574 L575 Y578 A643 S644 C649 K650 M651 L709 L714V574-V647 HydrophobicContact CG1-CG2 3.55Å; L575-V647 HydrophobicContact CD2-CG1 4.12Å; L575-V647 HydrophobicContact CD2-CG2 4.15Å; Y578-V647 HydrophobicContact CD1-CB 3.85Å; Y578-V647 HydrophobicContact CD1-CG1 3.44Å; Y578-V647 VanDerWaalsContact CD1-CG1 3.44Å; Y578-V647 HydrophobicContact CD2-CB 4.44Å; Y578-V647 HydrophobicContact CE1-CG1 4.19Å; Y578-V647 HydrophobicContact CG-CB 3.73Å; Y578-V647 HydrophobicContact CG-CG1 3.86Å; A643-V647 PolarHBondContact O-N 3.08Å; S644-V647 WeakPolarHBondContact O-CG2 3.27Å; S644-V647 PolarHBondContact O-N 3.16Å; V647-C649 PolarHBondContact O-N 2.98Å; V647-K650 CarbonylContact O-C 3.55Å; V647-K650 WeakPolarHBondContact O-CB 3.47Å; V647-K650 PolarHBondContact O-N 2.7Å; V647-K650 VanDerWaalsContact O-N 3.11Å; V647-M651 HydrophobicContact CG2-CE 4.42Å; V647-M651 WeakPolarHBondContact O-CB 3.39Å; V647-M651 WeakPolarHBondContact O-CG 3.46Å; V647-M651 PolarHBondContact O-N 2.95Å; V647-L709 HydrophobicContact CG1-CD2 3.8Å; V647-L714 HydrophobicContact CG1-CD1 3.72Å
648M98.2Very high97.7Very high0 Ų026.4 Ų26.40%013%0.131CC..Hα-helixtrans-62.9-40.9173.7-71.9-57.6-66.900111.7V574 W594 C597 Q598 M601 S644 L645 K650 M651 A652 Y664V574-M648 HydrophobicContact CG1-CG 3.91Å; V574-M648 HydrophobicContact CG1-SD 3.68Å; W594-M648 HydrophobicContact CE3-CE 4.29Å; W594-M648 HydrophobicContact CH2-CE 3.8Å; W594-M648 HydrophobicContact CZ3-CE 3.51Å; W594-M648 HydrophobicContact CZ3-SD 4.26Å; C597-M648 HydrophobicContact CB-CE 4.2Å; C597-M648 HydrophobicContact CB-SD 3.87Å; Q598-M648 HydrophobicContact CG-CE 4.03Å; M601-M648 HydrophobicContact CE-CG 4.18Å; M601-M648 HydrophobicContact CG-CE 4.15Å; M601-M648 HydrophobicContact CG-CG 3.81Å; M601-M648 HydrophobicContact CG-SD 3.89Å; M601-M648 HydrophobicContact SD-CG 4.22Å; S644-M648 WeakPolarHBondContact O-CB 3.32Å; S644-M648 VanDerWaalsContact O-CG 3.23Å; S644-M648 WeakPolarHBondContact O-CG 3.21Å; S644-M648 PolarHBondContact O-N 2.94Å; L645-M648 PolarHBondContact O-N 3.26Å; M648-K650 VanDerWaalsContact C-N 3.29Å; M648-K650 PolarHBondContact O-N 2.59Å; M648-M651 HydrophobicContact CE-CE 4.43Å; M648-M651 HydrophobicContact CG-CE 4.27Å; M648-M651 PolarHBondContact O-N 3.49Å; M648-M651 HydrophobicContact SD-CE 3.19Å; M648-M651 WeakPolarHBondContact SD-CE 3.22Å; M648-A652 WeakPolarHBondContact O-CB 3.47Å; M648-A652 PolarHBondContact O-N 3.06Å; M648-Y664 HydrophobicContact CB-CD1 4.24Å; M648-Y664 HydrophobicContact CB-CD2 3.66Å; M648-Y664 HydrophobicContact CB-CE2 3.98Å; M648-Y664 HydrophobicContact CB-CG 3.81Å; M648-Y664 HydrophobicContact CE-CD2 4.29Å; M648-Y664 HydrophobicContact CE-CE1 4.43Å; M648-Y664 HydrophobicContact CE-CE2 3.42Å; M648-Y664 VanDerWaalsContact CE-CE2 3.42Å; M648-Y664 WeakPolarHBondContact CE-OH 3.39Å; M648-Y664 HydrophobicContact CG-CE2 4.43Å
649C97.4Very high97.7Very high0 Ų034.4 Ų34.40%017%0.169CC..Hα-helixtrans-58.9-42.8171.9-70.20000111.4L645 C646 V647 R653 Y661 Y664 K665 Y719L645-C649 PolarHBondContact O-N 3.43Å; L645-C649 PolarHBondContact O-SG 3.34Å; C646-C649 WeakPolarHBondContact O-CB 3.36Å; C646-C649 PolarHBondContact O-N 2.76Å; V647-C649 PolarHBondContact O-N 2.98Å; C649-R653 WeakPolarHBondContact O-CG 3.33Å; C649-R653 PolarHBondContact O-N 3.07Å; C649-Y661 HydrophobicContact CB-CD2 4.08Å; C649-Y661 HydrophobicContact CB-CE2 4.15Å; C649-Y661 WeakPolarHBondContact O-CD2 3.37Å; C649-Y664 VanDerWaalsContact SG-C 3.58Å; C649-K665 PolarHBondContact SG-N 2.98Å; C649-K665 VanDerWaalsContact SG-N 3.45Å; C649-Y719 HydrophobicContact CB-CE1 3.73Å
650K96.4Very high97.7Very high76 Ų7634.7 Ų34.733%0.3317%0.171SC..Hα-helixtrans-67.9-46.2179.6-175.863.8173.6-173.10112.2Y578 C646 V647 M648 R653 L654 L714 Y719Y578-K650 HydrophobicContact CE2-CB 4.18Å; Y578-K650 HydrophobicContact CE2-CG 3.58Å; Y578-K650 VanDerWaalsContact OH-CG 3.31Å; Y578-K650 WeakPolarHBondContact OH-CG 3.12Å; C646-K650 PolarHBondContact O-N 3.16Å; C646-K650 VanDerWaalsContact O-N 3.08Å; V647-K650 CarbonylContact O-C 3.55Å; V647-K650 WeakPolarHBondContact O-CB 3.47Å; V647-K650 PolarHBondContact O-N 2.7Å; V647-K650 VanDerWaalsContact O-N 3.11Å; M648-K650 VanDerWaalsContact C-N 3.29Å; M648-K650 PolarHBondContact O-N 2.59Å; K650-R653 WeakPolarHBondContact O-CB 3.41Å; K650-R653 PolarHBondContact O-N 2.83Å; K650-L654 HydrophobicContact CG-CD1 4.22Å; K650-L654 WeakPolarHBondContact O-CG 3.33Å; K650-L654 PolarHBondContact O-N 3.45Å; K650-L654 VanDerWaalsContact O-N 3.12Å; K650-L714 HydrophobicContact CB-CD2 4.47Å; K650-L714 HydrophobicContact CD-CD2 4.31Å; K650-L714 HydrophobicContact CG-CD2 4.11Å; K650-Y719 PolarHBondContact N-OH 2.91Å
651M97.9Very high97.7Very high0 Ų036.5 Ų36.50%018%0.178CC..Hα-helixtrans-62.5-43.6176.8-70.2-170.8-60.300111.5V574 V577 Y578 L590 W594 C597 V647 M648 R653 L654 V655V574-M651 HydrophobicContact CG1-CE 4.05Å; V577-M651 HydrophobicContact CG1-SD 4.35Å; Y578-M651 HydrophobicContact CD2-CG 3.49Å; Y578-M651 VanDerWaalsContact CD2-CG 3.49Å; Y578-M651 HydrophobicContact CD2-SD 4.13Å; Y578-M651 HydrophobicContact CE2-CG 4.23Å; Y578-M651 HydrophobicContact CG-CG 4.33Å; L590-M651 HydrophobicContact CD1-CB 4.36Å; L590-M651 HydrophobicContact CD1-CG 3.77Å; L590-M651 HydrophobicContact CD1-SD 3.62Å; W594-M651 HydrophobicContact CE3-CB 3.78Å; W594-M651 HydrophobicContact CE3-CE 4.49Å; W594-M651 HydrophobicContact CZ3-CB 3.57Å; W594-M651 HydrophobicContact CZ3-CE 4.36Å; C597-M651 HydrophobicContact CB-CE 4.24Å; V647-M651 HydrophobicContact CG2-CE 4.42Å; V647-M651 WeakPolarHBondContact O-CB 3.39Å; V647-M651 WeakPolarHBondContact O-CG 3.46Å; V647-M651 PolarHBondContact O-N 2.95Å; M648-M651 HydrophobicContact CE-CE 4.43Å; M648-M651 HydrophobicContact CG-CE 4.27Å; M648-M651 PolarHBondContact O-N 3.49Å; M648-M651 HydrophobicContact SD-CE 3.19Å; M648-M651 WeakPolarHBondContact SD-CE 3.22Å; M651-R653 PolarHBondContact O-N 2.84Å; M651-L654 WeakPolarHBondContact O-CA 3.25Å; M651-L654 WeakPolarHBondContact O-CB 3.37Å; M651-L654 PolarHBondContact O-N 2.86Å; M651-V655 WeakPolarHBondContact O-CG2 3.5Å; M651-V655 PolarHBondContact O-N 3.12Å
652A98.1Very high97.6Very high0 Ų044.4 Ų44.40%021%0.207CC..Hα-helixtrans-54.9-39.9175.800000112.1W594 M648 D656 S657 A660W594-A652 HydrophobicContact CH2-CB 3.75Å; W594-A652 HydrophobicContact CZ2-CB 4.4Å; W594-A652 HydrophobicContact CZ3-CB 4.45Å; M648-A652 WeakPolarHBondContact O-CB 3.47Å; M648-A652 PolarHBondContact O-N 3.06Å; A652-D656 PolarHBondContact O-N 3.33Å; A652-S657 PolarHBondContact O-N 2.91Å; A652-A660 HydrophobicContact CB-CB 4.12Å
653R96.3Very high97.6Very high113 Ų11349.4 Ų49.443%0.42623%0.226SC..Hα-helixtrans-68.2-36.7173.9-71.4-73.6-179.7-167.1-9.4113C649 K650 M651 V655 D656 E658 Y661C649-R653 WeakPolarHBondContact O-CG 3.33Å; C649-R653 PolarHBondContact O-N 3.07Å; K650-R653 WeakPolarHBondContact O-CB 3.41Å; K650-R653 PolarHBondContact O-N 2.83Å; M651-R653 PolarHBondContact O-N 2.84Å; R653-V655 VanDerWaalsContact C-N 3.34Å; R653-D656 PolarHBondContact O-N 3.18Å; R653-E658 IonicContact CZ-OE2 2.79Å; R653-E658 IonicContact NH1-OE2 3.51Å; R653-E658 PolarHBondContact NH1-OE2 3.47Å; R653-E658 IonicContact NH2-OE1 3.14Å; R653-E658 PolarHBondContact NH2-OE1 3.42Å; R653-E658 IonicContact NH2-OE2 3.31Å; R653-E658 PolarHBondContact NH2-OE2 3.48Å; R653-Y661 HydrophobicContact CG-CD2 3.62Å; R653-Y661 HydrophobicContact CG-CE2 3.95Å; R653-Y661 HydrophobicContact CG-CG 4.29Å
654L97Very high97.6Very high75 Ų7549.6 Ų49.639%0.39323%0.227SC..Hα-helixtrans-72.7-26.6180-69.6166.2000113.2Y578 F581 L590 K650 M651Y578-L654 HydrophobicContact CE2-CD1 4.04Å; F581-L654 HydrophobicContact CD1-CD1 4.32Å; F581-L654 HydrophobicContact CE1-CD1 3.49Å; F581-L654 VanDerWaalsContact CE1-CD1 3.49Å; F581-L654 HydrophobicContact CZ-CD1 4.02Å; L590-L654 HydrophobicContact CD2-CB 3.88Å; L590-L654 HydrophobicContact CD2-CD1 3.97Å; K650-L654 HydrophobicContact CG-CD1 4.22Å; K650-L654 WeakPolarHBondContact O-CG 3.33Å; K650-L654 PolarHBondContact O-N 3.45Å; K650-L654 VanDerWaalsContact O-N 3.12Å; M651-L654 WeakPolarHBondContact O-CA 3.25Å; M651-L654 WeakPolarHBondContact O-CB 3.37Å; M651-L654 PolarHBondContact O-N 2.86Å
655V97.1Very high97.5Very high39 Ų3953.5 Ų53.524%0.23624%0.244CC..THydrogen-bonded Turntrans-10315.1176-53.40000112.9L590 W594 M651 R653 S657L590-V655 HydrophobicContact CD2-CG1 4.36Å; L590-V655 HydrophobicContact CG-CG1 4.35Å; W594-V655 HydrophobicContact CB-CG1 4.5Å; W594-V655 HydrophobicContact CD2-CG2 3.75Å; W594-V655 HydrophobicContact CE3-CG2 4.28Å; W594-V655 HydrophobicContact CG-CG1 4.34Å; W594-V655 HydrophobicContact CG-CG2 4.08Å; W594-V655 HydrophobicContact CZ2-CG2 4Å; M651-V655 WeakPolarHBondContact O-CG2 3.5Å; M651-V655 PolarHBondContact O-N 3.12Å; R653-V655 VanDerWaalsContact C-N 3.34Å; V655-S657 VanDerWaalsContact C-N 3.27Å; V655-S657 PolarHBondContact O-N 3.44Å
656D97.3Very high97.5Very high152 Ų15257.3 Ų57.381%0.81326%0.264SS*.THydrogen-bonded Turntrans5632.6177.9-61.5-47.8000115.2A652 R653 E658A652-D656 PolarHBondContact O-N 3.33Å; R653-D656 PolarHBondContact O-N 3.18Å; D656-E658 PolarHBondContact O-N 3.14Å
657S97.6Very high97.5Very high33 Ų3357.8 Ų57.823%0.23127%0.267CS..  trans-96.485.7176-169.50000112.2A652 V655 E659 A660 Y661A652-S657 PolarHBondContact O-N 2.91Å; V655-S657 VanDerWaalsContact C-N 3.27Å; V655-S657 PolarHBondContact O-N 3.44Å; S657-E659 PolarHBondContact O-N 3.04Å; S657-A660 VanDerWaalsContact OG-CB 3.25Å; S657-A660 WeakPolarHBondContact OG-CB 3.49Å; S657-Y661 PolarHBondContact O-N 3.14Å
658E97.6Very high97.5Very high65 Ų6558.1 Ų58.130%0.30427%0.269SS..Hα-helixtrans-65.8-34.8179.9-179.562.9-15700113R653 D656 Y661 R662R653-E658 IonicContact CZ-OE2 2.79Å; R653-E658 IonicContact NH1-OE2 3.51Å; R653-E658 PolarHBondContact NH1-OE2 3.47Å; R653-E658 IonicContact NH2-OE1 3.14Å; R653-E658 PolarHBondContact NH2-OE1 3.42Å; R653-E658 IonicContact NH2-OE2 3.31Å; R653-E658 PolarHBondContact NH2-OE2 3.48Å; D656-E658 PolarHBondContact O-N 3.14Å; E658-Y661 PolarHBondContact O-N 2.87Å; E658-R662 WeakPolarHBondContact O-CG 3.43Å; E658-R662 PolarHBondContact O-N 2.86Å; E658-R662 IonicContact OE1-CZ 3.49Å; E658-R662 IonicContact OE1-NE 3.35Å; E658-R662 PolarHBondContact OE1-NE 3.15Å; E658-R662 IonicContact OE1-NH2 3.15Å; E658-R662 PolarHBondContact OE1-NH2 3.06Å
659E97.9Very high97.4Very high168 Ų16863.6 Ų63.679%0.78529%0.294SS*.Hα-helixtrans-63.7-50.2177.3-176.7-177.7170.400111.3S657 Y661 R662 R663S657-E659 PolarHBondContact O-N 3.04Å; E659-Y661 VanDerWaalsContact C-N 3.31Å; E659-Y661 PolarHBondContact O-N 3.45Å; E659-R662 PolarHBondContact O-N 3.31Å; E659-R663 PolarHBondContact O-N 2.9Å; E659-R663 VanDerWaalsContact O-N 3.08Å
660A97.9Very high97.4Very high8 Ų867.6 Ų67.67%0.06631%0.309CS..Hα-helixtrans-61.9-41.2177.100000111.2W594 A652 S657 R662 R663 Y664W594-A660 HydrophobicContact CH2-CB 4.11Å; W594-A660 HydrophobicContact CZ2-CB 3.9Å; A652-A660 HydrophobicContact CB-CB 4.12Å; S657-A660 VanDerWaalsContact OG-CB 3.25Å; S657-A660 WeakPolarHBondContact OG-CB 3.49Å; A660-R662 PolarHBondContact O-N 2.93Å; A660-R663 PolarHBondContact O-N 3.12Å; A660-Y664 HydrophobicContact CB-CD2 4.26Å; A660-Y664 HydrophobicContact CB-CE2 4.02Å; A660-Y664 WeakPolarHBondContact O-CD2 3.16Å; A660-Y664 PolarHBondContact O-N 3.16Å
661Y97.9Very high97.5Very high37 Ų3764 Ų6415%0.14529%0.294CS..Hα-helixtrans-56-49.1175.5171.8-95000111.8C649 R653 S657 E658 E659 R663 K665C649-Y661 HydrophobicContact CB-CD2 4.08Å; C649-Y661 HydrophobicContact CB-CE2 4.15Å; C649-Y661 WeakPolarHBondContact O-CD2 3.37Å; R653-Y661 HydrophobicContact CG-CD2 3.62Å; R653-Y661 HydrophobicContact CG-CE2 3.95Å; R653-Y661 HydrophobicContact CG-CG 4.29Å; S657-Y661 PolarHBondContact O-N 3.14Å; E658-Y661 PolarHBondContact O-N 2.87Å; E659-Y661 VanDerWaalsContact C-N 3.31Å; E659-Y661 PolarHBondContact O-N 3.45Å; Y661-R663 VanDerWaalsContact C-N 3.35Å; Y661-R663 PolarHBondContact O-N 3.3Å; Y661-K665 HydrophobicContact CE1-CD 3.81Å; Y661-K665 WeakPolarHBondContact O-CB 3.43Å; Y661-K665 PolarHBondContact O-N 3.32Å
662R97.9Very high97.4Very high166 Ų16664.8 Ų64.863%0.62630%0.299SS*.Hα-helixtrans-63.1-42.3-179.5-71.1176-171176.83111.8E658 E659 A660 K665 D666E658-R662 WeakPolarHBondContact O-CG 3.43Å; E658-R662 PolarHBondContact O-N 2.86Å; E658-R662 IonicContact OE1-CZ 3.49Å; E658-R662 IonicContact OE1-NE 3.35Å; E658-R662 PolarHBondContact OE1-NE 3.15Å; E658-R662 IonicContact OE1-NH2 3.15Å; E658-R662 PolarHBondContact OE1-NH2 3.06Å; E659-R662 PolarHBondContact O-N 3.31Å; A660-R662 PolarHBondContact O-N 2.93Å; R662-K665 PolarHBondContact O-N 2.84Å; R662-D666 PolarHBondContact O-N 2.6Å
663R98Very high97.4Very high105 Ų10567.7 Ų67.740%0.39632%0.324SS..Hα-helixtrans-60.9-52.2177.9-177.4-179.9-179.6-171.20.9111.9E602 E659 A660 Y661 K665 D666 L667E602-R663 VanDerWaalsContact CD-NH2 3.27Å; E602-R663 IonicContact OE1-NH2 3.47Å; E602-R663 PolarHBondContact OE1-NH2 2.89Å; E602-R663 IonicContact OE2-CZ 3.72Å; E602-R663 IonicContact OE2-NH1 3.79Å; E602-R663 PolarHBondContact OE2-NH1 3.37Å; E602-R663 IonicContact OE2-NH2 2.57Å; E602-R663 PolarHBondContact OE2-NH2 3.04Å; E659-R663 PolarHBondContact O-N 2.9Å; E659-R663 VanDerWaalsContact O-N 3.08Å; A660-R663 PolarHBondContact O-N 3.12Å; Y661-R663 VanDerWaalsContact C-N 3.35Å; Y661-R663 PolarHBondContact O-N 3.3Å; R663-K665 VanDerWaalsContact C-N 3.31Å; R663-K665 PolarHBondContact O-N 3.27Å; R663-D666 PolarHBondContact O-N 2.73Å; R663-L667 HydrophobicContact CG-CD1 4.39Å; R663-L667 PolarHBondContact O-N 2.84Å
664Y97.9Very high97.5Very high5 Ų562.7 Ų62.72%0.0231%0.306CS..Hα-helixtrans-69.6-30.8-178.6-65.7-53.6000112.4W594 M601 L645 M648 C649 A660 L667 L668W594-Y664 HydrophobicContact CH2-CE2 4.26Å; M601-Y664 HydrophobicContact CB-CE1 4.23Å; L645-Y664 HydrophobicContact CD2-CD1 3.72Å; L645-Y664 HydrophobicContact CD2-CG 4.44Å; M648-Y664 HydrophobicContact CB-CD1 4.24Å; M648-Y664 HydrophobicContact CB-CD2 3.66Å; M648-Y664 HydrophobicContact CB-CE2 3.98Å; M648-Y664 HydrophobicContact CB-CG 3.81Å; M648-Y664 HydrophobicContact CE-CD2 4.29Å; M648-Y664 HydrophobicContact CE-CE1 4.43Å; M648-Y664 HydrophobicContact CE-CE2 3.42Å; M648-Y664 VanDerWaalsContact CE-CE2 3.42Å; M648-Y664 WeakPolarHBondContact CE-OH 3.39Å; M648-Y664 HydrophobicContact CG-CE2 4.43Å; C649-Y664 VanDerWaalsContact SG-C 3.58Å; A660-Y664 HydrophobicContact CB-CD2 4.26Å; A660-Y664 HydrophobicContact CB-CE2 4.02Å; A660-Y664 WeakPolarHBondContact O-CD2 3.16Å; A660-Y664 PolarHBondContact O-N 3.16Å; Y664-L667 HydrophobicContact CD1-CD1 4.26Å; Y664-L668 VanDerWaalsContact O-CB 3.23Å; Y664-L668 WeakPolarHBondContact O-CB 3.26Å; Y664-L668 PolarHBondContact O-N 3.48Å
665K96.8Very high97.5Very high81 Ų8159.2 Ų59.235%0.35229%0.288SS..Hα-helixtrans-65.8-43.5174.5-173.6-179.8-178.4-178.10112.1C649 Y661 R662 R663 L668 E669C649-K665 PolarHBondContact SG-N 2.98Å; C649-K665 VanDerWaalsContact SG-N 3.45Å; Y661-K665 HydrophobicContact CE1-CD 3.81Å; Y661-K665 WeakPolarHBondContact O-CB 3.43Å; Y661-K665 PolarHBondContact O-N 3.32Å; R662-K665 PolarHBondContact O-N 2.84Å; R663-K665 VanDerWaalsContact C-N 3.31Å; R663-K665 PolarHBondContact O-N 3.27Å; K665-L668 WeakPolarHBondContact O-CB 3.33Å; K665-L668 PolarHBondContact O-N 3.04Å; K665-E669 WeakPolarHBondContact CE-OE1 3.39Å; K665-E669 WeakPolarHBondContact O-CG 3.38Å; K665-E669 PolarHBondContact O-N 3.36Å
666D97.1Very high97.5Very high80 Ų8059.9 Ų59.943%0.42829%0.29SS..Hα-helixtrans-59.4-48.9175.3173.283.6000111.7R662 R663 L668 E669 R670R662-D666 PolarHBondContact O-N 2.6Å; R663-D666 PolarHBondContact O-N 2.73Å; D666-L668 VanDerWaalsContact C-N 3.29Å; D666-L668 PolarHBondContact O-N 3.1Å; D666-E669 PolarHBondContact O-N 3.31Å; D666-R670 PolarHBondContact O-N 3.49Å; D666-R670 VanDerWaalsContact O-N 3.09Å; D666-R670 IonicContact OD1-NE 3.66Å; D666-R670 IonicContact OD2-CZ 3.43Å; D666-R670 IonicContact OD2-NE 3.05Å; D666-R670 PolarHBondContact OD2-NE 3.22Å; D666-R670 IonicContact OD2-NH2 2.67Å; D666-R670 PolarHBondContact OD2-NH2 2.67Å
667L97.8Very high97.4Very high10 Ų1061 Ų615%0.05229%0.288CS..Hα-helixtrans-57.6-43.4175.5-76162.5000111.6L605 L645 R663 Y664 G671L605-L667 HydrophobicContact CD2-CD1 3.85Å; L605-L667 HydrophobicContact CD2-CD2 3.95Å; L645-L667 HydrophobicContact CD1-CB 3.93Å; L645-L667 HydrophobicContact CD2-CB 3.93Å; L645-L667 HydrophobicContact CD2-CD1 4.21Å; R663-L667 HydrophobicContact CG-CD1 4.39Å; R663-L667 PolarHBondContact O-N 2.84Å; Y664-L667 HydrophobicContact CD1-CD1 4.26Å; L667-G671 PolarHBondContact O-N 2.62Å
668L97.6Very high97.5Very high8 Ų862.6 Ų62.64%0.04229%0.293CS..Hα-helixtrans-63.2-43.6179.6-179.460.6000111.9L642 L645 Y664 K665 D666 S672 Y719 A721L642-L668 HydrophobicContact CB-CD1 4.3Å; L642-L668 HydrophobicContact CD2-CD1 4.27Å; L645-L668 HydrophobicContact CB-CB 4.12Å; L645-L668 HydrophobicContact CB-CD1 3.97Å; L645-L668 HydrophobicContact CD1-CB 4.34Å; Y664-L668 VanDerWaalsContact O-CB 3.23Å; Y664-L668 WeakPolarHBondContact O-CB 3.26Å; Y664-L668 PolarHBondContact O-N 3.48Å; K665-L668 WeakPolarHBondContact O-CB 3.33Å; K665-L668 PolarHBondContact O-N 3.04Å; D666-L668 VanDerWaalsContact C-N 3.29Å; D666-L668 PolarHBondContact O-N 3.1Å; L668-S672 WeakPolarHBondContact O-CB 3.46Å; L668-S672 PolarHBondContact O-N 2.91Å; L668-S672 PolarHBondContact O-OG 2.57Å; L668-Y719 HydrophobicContact CD2-CD1 3.65Å; L668-Y719 HydrophobicContact CD2-CE1 4.49Å; L668-Y719 HydrophobicContact CD2-CG 4.17Å; L668-A721 HydrophobicContact CD1-CB 4Å
669E96.1Very high97.5Very high114 Ų11459.5 Ų59.553%0.53328%0.279SS..Hα-helixtrans-64.9-47.2180-74.4175.1-179.600111.5K665 D666 A673K665-E669 WeakPolarHBondContact CE-OE1 3.39Å; K665-E669 WeakPolarHBondContact O-CG 3.38Å; K665-E669 PolarHBondContact O-N 3.36Å; D666-E669 PolarHBondContact O-N 3.31Å; E669-A673 PolarHBondContact O-N 3.2Å
670R97.5Very high97.5Very high84 Ų8453.9 Ų53.932%0.31725%0.251SS..Hα-helixtrans-66.5-49.7177.9-64.6-172.1-73.7106.72.4111.8G611 D612 G613 D666 S672 A673 A674G611-R670 PolarHBondContact O-NH1 3.01Å; D612-R670 CarbonylContact O-C 3.28Å; D612-R670 WeakPolarHBondContact O-CB 3.34Å; G613-R670 VanDerWaalsContact N-NH1 3.14Å; D666-R670 PolarHBondContact O-N 3.49Å; D666-R670 VanDerWaalsContact O-N 3.09Å; D666-R670 IonicContact OD1-NE 3.66Å; D666-R670 IonicContact OD2-CZ 3.43Å; D666-R670 IonicContact OD2-NE 3.05Å; D666-R670 PolarHBondContact OD2-NE 3.22Å; D666-R670 IonicContact OD2-NH2 2.67Å; D666-R670 PolarHBondContact OD2-NH2 2.67Å; R670-S672 VanDerWaalsContact C-N 3.34Å; R670-S672 PolarHBondContact O-N 3.03Å; R670-A673 WeakPolarHBondContact O-CB 3.47Å; R670-A673 PolarHBondContact O-N 2.87Å; R670-A673 VanDerWaalsContact O-N 3.13Å; R670-A674 PolarHBondContact O-N 2.91Å
671G97.9Very high97.5Very high0 Ų056.5 Ų56.50%026%0.263CS..Hα-helixtrans-62.5-36.9179.700000113.2D612 G613 L642 L667 A673 A674 F675D612-G671 PolarHBondContact O-N 3.47Å; G613-G671 WeakPolarHBondContact O-CA 3.41Å; L642-G671 VanDerWaalsContact CD2-C 3.49Å; L667-G671 PolarHBondContact O-N 2.62Å; G671-A673 VanDerWaalsContact C-N 3.35Å; G671-A674 PolarHBondContact O-N 2.78Å; G671-F675 VanDerWaalsContact O-CB 3.27Å; G671-F675 WeakPolarHBondContact O-CB 3.4Å; G671-F675 PolarHBondContact O-N 2.96Å
672S96.9Very high97.4Very high17 Ų1756 Ų5612%0.11927%0.27CS..Hα-helixtrans-64.9-40.1175.6-60.40000111.6L668 R670 D676 A721L668-S672 WeakPolarHBondContact O-CB 3.46Å; L668-S672 PolarHBondContact O-N 2.91Å; L668-S672 PolarHBondContact O-OG 2.57Å; R670-S672 VanDerWaalsContact C-N 3.34Å; R670-S672 PolarHBondContact O-N 3.03Å; S672-D676 WeakPolarHBondContact O-CB 3.35Å; S672-D676 PolarHBondContact O-N 3.07Å; S672-D676 VanDerWaalsContact O-N 3.12Å; S672-A721 WeakPolarHBondContact OG-CA 3.24Å; S672-A721 WeakPolarHBondContact OG-CB 3.36Å
673A96.6Very high97.3Very high62 Ų6254.7 Ų54.751%0.51227%0.269SS..Hα-helixtrans-66.5-41.2176.100000111.9E669 R670 G671 K677E669-A673 PolarHBondContact O-N 3.2Å; R670-A673 WeakPolarHBondContact O-CB 3.47Å; R670-A673 PolarHBondContact O-N 2.87Å; R670-A673 VanDerWaalsContact O-N 3.13Å; G671-A673 VanDerWaalsContact C-N 3.35Å; A673-K677 VanDerWaalsContact O-CB 3.27Å; A673-K677 WeakPolarHBondContact O-CB 3.45Å; A673-K677 PolarHBondContact O-N 3.44Å; A673-K677 VanDerWaalsContact O-N 3.07Å
674A98.1Very high97.4Very high8 Ų850.3 Ų50.37%0.06625%0.252CS..Hα-helixtrans-62.6-49.2174.600000112.2D612 L614 R670 G671 D676 K677 L678D612-A674 HydrophobicContact CB-CB 4.25Å; D612-A674 WeakPolarHBondContact OD2-CB 3.4Å; L614-A674 HydrophobicContact CB-CB 4.01Å; L614-A674 HydrophobicContact CD2-CB 4.04Å; R670-A674 PolarHBondContact O-N 2.91Å; G671-A674 PolarHBondContact O-N 2.78Å; A674-D676 VanDerWaalsContact C-N 3.32Å; A674-D676 PolarHBondContact O-N 2.9Å; A674-K677 PolarHBondContact O-N 3Å; A674-L678 WeakPolarHBondContact O-CB 3.23Å; A674-L678 VanDerWaalsContact O-CG 3.27Å; A674-L678 WeakPolarHBondContact O-CG 3.48Å; A674-L678 PolarHBondContact O-N 3.28Å
675F98Very high97.4Very high2 Ų250.1 Ų50.11%0.00925%0.252CS..Hα-helixtrans-57.7-46.3-179.1-175.6-92.7000111.3L614 G639 L642 G671 L679 Y685 F722L614-F675 HydrophobicContact CD1-CB 4.37Å; L614-F675 HydrophobicContact CD1-CD2 4.17Å; L614-F675 HydrophobicContact CD2-CB 3.92Å; L614-F675 HydrophobicContact CD2-CD2 4.27Å; G639-F675 VanDerWaalsContact N-CE2 3.34Å; L642-F675 HydrophobicContact CD1-CB 3.65Å; L642-F675 HydrophobicContact CD1-CD1 4.08Å; L642-F675 HydrophobicContact CD1-CD2 4.12Å; L642-F675 HydrophobicContact CD1-CG 3.69Å; G671-F675 VanDerWaalsContact O-CB 3.27Å; G671-F675 WeakPolarHBondContact O-CB 3.4Å; G671-F675 PolarHBondContact O-N 2.96Å; F675-L679 HydrophobicContact CD2-CD1 3.52Å; F675-L679 HydrophobicContact CE2-CD1 3.38Å; F675-L679 HydrophobicContact CG-CD1 4.2Å; F675-L679 HydrophobicContact CZ-CD1 3.99Å; F675-L679 WeakPolarHBondContact O-CB 3.48Å; F675-L679 PolarHBondContact O-N 3.36Å; F675-Y685 HydrophobicContact CD1-CD1 4.21Å; F675-Y685 AromaticContact CD1-CE1 3.93Å; F675-Y685 HydrophobicContact CD1-CE1 3.93Å; F675-Y685 AromaticContact CE1-CD1 3.53Å; F675-Y685 HydrophobicContact CE1-CD1 3.53Å; F675-Y685 AromaticContact CE1-CE1 3.47Å; F675-Y685 HydrophobicContact CE1-CE1 3.47Å; F675-Y685 VanDerWaalsContact CE1-CE1 3.47Å; F675-Y685 HydrophobicContact CE1-CG 4.11Å; F675-Y685 AromaticContact CE1-CZ 3.99Å; F675-Y685 HydrophobicContact CZ-CD1 4.16Å; F675-Y685 HydrophobicContact CZ-CE1 4.48Å; F675-Y685 HydrophobicContact CZ-CG 4.41Å; F675-F722 HydrophobicContact CE1-CE1 4.42Å
676D96.3Very high97.5Very high52 Ų5247.7 Ų47.728%0.27824%0.243SC..Hα-helixtrans-63.5-48177.4-160.968000112S672 A674 L678 W680 K726S672-D676 WeakPolarHBondContact O-CB 3.35Å; S672-D676 PolarHBondContact O-N 3.07Å; S672-D676 VanDerWaalsContact O-N 3.12Å; A674-D676 VanDerWaalsContact C-N 3.32Å; A674-D676 PolarHBondContact O-N 2.9Å; D676-L678 VanDerWaalsContact C-N 3.33Å; D676-L678 PolarHBondContact O-N 3.37Å; D676-W680 WeakPolarHBondContact O-CB 3.2Å; D676-W680 PolarHBondContact O-N 2.98Å; D676-K726 WeakPolarHBondContact OD1-CD 3.09Å; D676-K726 IonicContact OD1-NZ 2.9Å; D676-K726 PolarHBondContact OD1-NZ 2.85Å; D676-K726 IonicContact OD2-NZ 2.63Å; D676-K726 PolarHBondContact OD2-NZ 3.18Å
677K97Very high97.5Very high177 Ų17744.4 Ų44.477%0.7722%0.224SC*.Hα-helixtrans-61.4-39.6-179179-174.2172.2-165.60112.6A673 A674A673-K677 VanDerWaalsContact O-CB 3.27Å; A673-K677 WeakPolarHBondContact O-CB 3.45Å; A673-K677 PolarHBondContact O-N 3.44Å; A673-K677 VanDerWaalsContact O-N 3.07Å; A674-K677 PolarHBondContact O-N 3Å
678L97.7Very high97.5Very high65 Ų6544.3 Ų44.334%0.3422%0.224SC..Hα-helixtrans-87.9-34.8-171.2-67173000113.1L614 P633 A674 D676L614-L678 HydrophobicContact CD2-CD1 4.4Å; P633-L678 HydrophobicContact CB-CD1 4.28Å; P633-L678 HydrophobicContact CG-CD1 3.87Å; A674-L678 WeakPolarHBondContact O-CB 3.23Å; A674-L678 VanDerWaalsContact O-CG 3.27Å; A674-L678 WeakPolarHBondContact O-CG 3.48Å; A674-L678 PolarHBondContact O-N 3.28Å; D676-L678 VanDerWaalsContact C-N 3.33Å; D676-L678 PolarHBondContact O-N 3.37Å
679L98.2Very high97.5Very high0 Ų045.9 Ų45.90%024%0.235CC..Hα-helixtrans-112.6-27.3-168-61.1170.5000113.9S634 F675 N681 Y685 N686S634-L679 VanDerWaalsContact C-CD1 3.48Å; F675-L679 HydrophobicContact CD2-CD1 3.52Å; F675-L679 HydrophobicContact CE2-CD1 3.38Å; F675-L679 HydrophobicContact CG-CD1 4.2Å; F675-L679 HydrophobicContact CZ-CD1 3.99Å; F675-L679 WeakPolarHBondContact O-CB 3.48Å; F675-L679 PolarHBondContact O-N 3.36Å; L679-N681 PolarHBondContact O-N 3.06Å; L679-Y685 HydrophobicContact CB-CD1 4.13Å; L679-Y685 CarbonylContact O-C 3.55Å; L679-Y685 WeakPolarHBondContact O-CA 2.96Å; L679-N686 HydrophobicContact CD2-CB 4.38Å; L679-N686 PolarHBondContact O-N 3.25Å
680W98.1Very high97.5Very high51 Ų5142.2 Ų42.219%0.19322%0.222CC..BIsolated β-bridgetrans-74116-178.3179.8-109.5000111.8D676 G682 K683 Y685 K726 R729D676-W680 WeakPolarHBondContact O-CB 3.2Å; D676-W680 PolarHBondContact O-N 2.98Å; W680-G682 WeakPolarHBondContact CZ2-O 3.17Å; W680-K683 VanDerWaalsContact CH2-C 3.46Å; W680-K683 VanDerWaalsContact CH2-O 3.3Å; W680-K683 WeakPolarHBondContact CH2-O 3.09Å; W680-Y685 HydrophobicContact CB-CD1 4.19Å; W680-Y685 HydrophobicContact CB-CE1 4.03Å; W680-Y685 HydrophobicContact CD2-CE1 4.47Å; W680-Y685 HydrophobicContact CE3-CD1 4.04Å; W680-Y685 HydrophobicContact CE3-CD2 4.3Å; W680-Y685 AromaticContact CE3-CE1 3.82Å; W680-Y685 HydrophobicContact CE3-CE1 3.82Å; W680-Y685 HydrophobicContact CE3-CE2 4.11Å; W680-Y685 HydrophobicContact CE3-CG 4.28Å; W680-Y685 AromaticContact CE3-CZ 3.87Å; W680-Y685 HydrophobicContact CZ3-CD2 4.5Å; W680-Y685 HydrophobicContact CZ3-CE2 4.25Å; W680-K726 VanDerWaalsContact CD1-NZ 3.29Å; W680-K726 HydrophobicContact CD2-CB 4.48Å; W680-K726 HydrophobicContact CD2-CD 3.69Å; W680-K726 HydrophobicContact CD2-CG 4.15Å; W680-K726 HydrophobicContact CE3-CB 4.1Å; W680-K726 HydrophobicContact CE3-CD 4.06Å; W680-K726 HydrophobicContact CE3-CG 4.27Å; W680-K726 HydrophobicContact CG-CD 4.02Å; W680-K726 HydrophobicContact CH2-CB 3.76Å; W680-K726 HydrophobicContact CH2-CD 4.47Å; W680-K726 HydrophobicContact CH2-CG 3.87Å; W680-K726 HydrophobicContact CZ2-CB 4.17Å; W680-K726 HydrophobicContact CZ2-CD 4.14Å; W680-K726 HydrophobicContact CZ2-CG 3.74Å; W680-K726 HydrophobicContact CZ3-CB 3.72Å; W680-K726 HydrophobicContact CZ3-CD 4.44Å; W680-K726 HydrophobicContact CZ3-CG 4.13Å; W680-R729 HydrophobicContact CH2-CB 4.2Å; W680-R729 HydrophobicContact CH2-CG 4.47Å
681N97.4Very high97.2Very high62 Ų6241.5 Ų41.533%0.33224%0.241SC..  trans-997-178.968.627.7000114.4L679 K683 Y684 N686L679-N681 PolarHBondContact O-N 3.06Å; N681-K683 PolarHBondContact OD1-N 3.45Å; N681-Y684 PolarHBondContact N-O 3.27Å; N681-Y684 VanDerWaalsContact N-O 3.13Å; N681-Y684 VanDerWaalsContact ND2-CD2 3.33Å; N681-Y684 WeakPolarHBondContact ND2-CD2 3.23Å; N681-Y684 WeakPolarHBondContact ND2-CE2 3.44Å; N681-Y684 PolarHBondContact ND2-O 2.89Å; N681-Y684 PolarHBondContact OD1-N 3.42Å; N681-Y684 PolarHBondContact OD1-O 2.76Å; N681-N686 PolarHBondContact ND2-OD1 3.29Å
682G96.5Very high96.9Very high28 Ų2848.3 Ų48.329%0.28927%0.267SS..SBendtrans96.3-14.8-175.600000115W680 R729W680-G682 WeakPolarHBondContact CZ2-O 3.17Å; G682-R729 WeakPolarHBondContact O-CD 3.32Å; G682-R729 PolarHBondContact O-NH1 3.45Å
683K96.8Very high96.4Very high138 Ų13851.6 Ų51.660%0.630%0.295SS*.SBendtrans-123.7-48.6177.5-66.3-176.1179-179.20112.8W680 N681 R729 A730W680-K683 VanDerWaalsContact CH2-C 3.46Å; W680-K683 VanDerWaalsContact CH2-O 3.3Å; W680-K683 WeakPolarHBondContact CH2-O 3.09Å; N681-K683 PolarHBondContact OD1-N 3.45Å; K683-R729 CarbonylContact O-C 3.58Å; K683-R729 WeakPolarHBondContact O-CD 3.35Å; K683-R729 WeakPolarHBondContact O-CG 3.4Å; K683-A730 PolarHBondContact O-N 3.3Å
684Y98.4Very high96.2Very high13 Ų1351.8 Ų51.85%0.05129%0.287CS..SBendtrans-146.6176.4-177.457.9-94.3000109.2N681 N696 I698N681-Y684 PolarHBondContact N-O 3.27Å; N681-Y684 VanDerWaalsContact N-O 3.13Å; N681-Y684 VanDerWaalsContact ND2-CD2 3.33Å; N681-Y684 WeakPolarHBondContact ND2-CD2 3.23Å; N681-Y684 WeakPolarHBondContact ND2-CE2 3.44Å; N681-Y684 PolarHBondContact ND2-O 2.89Å; N681-Y684 PolarHBondContact OD1-N 3.42Å; N681-Y684 PolarHBondContact OD1-O 2.76Å; Y684-N696 WeakPolarHBondContact CE2-O 3.46Å; Y684-N696 PolarHBondContact OH-O 3.39Å; Y684-I698 HydrophobicContact CD1-CG1 3.99Å; Y684-I698 HydrophobicContact CD2-CG1 3.91Å; Y684-I698 HydrophobicContact CE1-CD1 4.01Å; Y684-I698 HydrophobicContact CE1-CG1 3.71Å; Y684-I698 HydrophobicContact CE2-CB 4.49Å; Y684-I698 HydrophobicContact CE2-CD1 4.21Å; Y684-I698 HydrophobicContact CE2-CG1 3.63Å; Y684-I698 HydrophobicContact CG-CG1 4.1Å
685Y98.4Very high96Very high1 Ų152.1 Ų52.10%0.00429%0.288CS..BIsolated β-bridgetrans-89.5125.4173-62-81.8000109.4F675 L679 W680 Q702 K726 I727 A730F675-Y685 HydrophobicContact CD1-CD1 4.21Å; F675-Y685 AromaticContact CD1-CE1 3.93Å; F675-Y685 HydrophobicContact CD1-CE1 3.93Å; F675-Y685 AromaticContact CE1-CD1 3.53Å; F675-Y685 HydrophobicContact CE1-CD1 3.53Å; F675-Y685 AromaticContact CE1-CE1 3.47Å; F675-Y685 HydrophobicContact CE1-CE1 3.47Å; F675-Y685 VanDerWaalsContact CE1-CE1 3.47Å; F675-Y685 HydrophobicContact CE1-CG 4.11Å; F675-Y685 AromaticContact CE1-CZ 3.99Å; F675-Y685 HydrophobicContact CZ-CD1 4.16Å; F675-Y685 HydrophobicContact CZ-CE1 4.48Å; F675-Y685 HydrophobicContact CZ-CG 4.41Å; L679-Y685 HydrophobicContact CB-CD1 4.13Å; L679-Y685 CarbonylContact O-C 3.55Å; L679-Y685 WeakPolarHBondContact O-CA 2.96Å; W680-Y685 HydrophobicContact CB-CD1 4.19Å; W680-Y685 HydrophobicContact CB-CE1 4.03Å; W680-Y685 HydrophobicContact CD2-CE1 4.47Å; W680-Y685 HydrophobicContact CE3-CD1 4.04Å; W680-Y685 HydrophobicContact CE3-CD2 4.3Å; W680-Y685 AromaticContact CE3-CE1 3.82Å; W680-Y685 HydrophobicContact CE3-CE1 3.82Å; W680-Y685 HydrophobicContact CE3-CE2 4.11Å; W680-Y685 HydrophobicContact CE3-CG 4.28Å; W680-Y685 AromaticContact CE3-CZ 3.87Å; W680-Y685 HydrophobicContact CZ3-CD2 4.5Å; W680-Y685 HydrophobicContact CZ3-CE2 4.25Å; Y685-Q702 PolarHBondContact O-OE1 2.85Å; Y685-K726 WeakPolarHBondContact OH-CB 3.33Å; Y685-I727 HydrophobicContact CE2-CD1 4.25Å; Y685-A730 HydrophobicContact CD2-CB 4.21Å; Y685-A730 HydrophobicContact CE2-CB 4.45Å
686N98.6Very high96Very high30 Ų3054.3 Ų54.316%0.1630%0.3CS..  trans-54.1147.4172.8-73.7-21.1000110.4A635 L679 N681 D688 S695A635-N686 WeakPolarHBondContact CB-O 3.19Å; L679-N686 HydrophobicContact CD2-CB 4.38Å; L679-N686 PolarHBondContact O-N 3.25Å; N681-N686 PolarHBondContact ND2-OD1 3.29Å; N686-D688 VanDerWaalsContact C-N 3.33Å; N686-D688 PolarHBondContact O-N 3.01Å; N686-S695 CarbonylContact C-O 3.41Å; N686-S695 WeakPolarHBondContact CB-O 3.22Å
687Y98.3Very high96.1Very high11 Ų1151.8 Ų51.84%0.04329%0.287CS..SBendtrans-54.1-49.8177.6171.9-107.3000111.7W628 T629 V630 S634 A635 S695 S697 M699W628-Y687 AromaticContact CD1-CZ 3.95Å; W628-Y687 VanDerWaalsContact CD1-OH 3.29Å; W628-Y687 AromaticContact CD2-CE2 3.75Å; W628-Y687 HydrophobicContact CD2-CE2 3.75Å; W628-Y687 AromaticContact CD2-CZ 3.73Å; W628-Y687 AromaticContact CE2-CE2 3.62Å; W628-Y687 AromaticContact CE2-CZ 3.55Å; W628-Y687 AromaticContact CE3-CE2 3.9Å; W628-Y687 HydrophobicContact CE3-CE2 3.9Å; W628-Y687 HydrophobicContact CG-CE2 4.45Å; W628-Y687 AromaticContact CG-CZ 3.99Å; W628-Y687 AromaticContact CH2-CD2 3.99Å; W628-Y687 HydrophobicContact CH2-CD2 3.99Å; W628-Y687 AromaticContact CH2-CE2 3.82Å; W628-Y687 HydrophobicContact CH2-CE2 3.82Å; W628-Y687 AromaticContact CZ2-CD2 3.92Å; W628-Y687 HydrophobicContact CZ2-CD2 3.92Å; W628-Y687 AromaticContact CZ2-CE2 3.67Å; W628-Y687 HydrophobicContact CZ2-CE2 3.67Å; W628-Y687 HydrophobicContact CZ2-CG 4.46Å; W628-Y687 HydrophobicContact CZ3-CD2 4.46Å; W628-Y687 AromaticContact CZ3-CE2 3.93Å; W628-Y687 HydrophobicContact CZ3-CE2 3.93Å; W628-Y687 AromaticContact NE1-CZ 3.71Å; W628-Y687 PolarHBondContact O-OH 3.42Å; T629-Y687 VanDerWaalsContact O-CE1 3.3Å; T629-Y687 WeakPolarHBondContact O-CE1 3.12Å; T629-Y687 PolarHBondContact O-OH 3.26Å; V630-Y687 HydrophobicContact CG2-CE1 4.22Å; V630-Y687 HydrophobicContact CG2-CE2 4.39Å; V630-Y687 WeakPolarHBondContact CG2-OH 3.42Å; S634-Y687 WeakPolarHBondContact CA-O 3.41Å; S634-Y687 WeakPolarHBondContact CB-O 3.24Å; A635-Y687 PolarHBondContact N-O 3.2Å; Y687-S695 WeakPolarHBondContact CB-O 3.36Å; Y687-S695 PolarHBondContact N-O 2.85Å; Y687-S697 PolarHBondContact N-O 3.38Å; Y687-M699 HydrophobicContact CD2-CB 4.15Å; Y687-M699 HydrophobicContact CD2-CG 4.4Å; Y687-M699 HydrophobicContact CD2-SD 3.93Å; Y687-M699 HydrophobicContact CE2-SD 3.99Å
688D98.1Very high96.1Very high8 Ų843.4 Ų43.44%0.04325%0.25CS..BIsolated β-bridgetrans-145.3171.6172.374.820.5000112.4V630 T631 P633 N686 S690 S695V630-D688 HydrophobicContact CG1-CB 3.9Å; T631-D688 PolarHBondContact N-OD2 2.78Å; T631-D688 WeakPolarHBondContact O-CB 3.47Å; P633-D688 CarbonylContact O-C 3.49Å; P633-D688 WeakPolarHBondContact O-CA 3.43Å; N686-D688 VanDerWaalsContact C-N 3.33Å; N686-D688 PolarHBondContact O-N 3.01Å; D688-S690 WeakPolarHBondContact OD1-CB 3.41Å; D688-S690 PolarHBondContact OD1-N 3.01Å; D688-S690 PolarHBondContact OD1-OG 2.8Å; D688-S690 PolarHBondContact OD2-OG 2.54Å; D688-S695 PolarHBondContact N-O 2.8Å; D688-S695 WeakPolarHBondContact O-CB 3.15Å; D688-S695 WeakPolarHBondContact OD1-CA 3.28Å; D688-S695 WeakPolarHBondContact OD1-CB 3.41Å
689S97.1Very high96.2Very high40 Ų4040.5 Ų40.528%0.2824%0.235SC..SBendtrans-9413-179.477.50000113.5P633 G691P633-S689 VanDerWaalsContact CD-OG 3.23Å; P633-S689 WeakPolarHBondContact CD-OG 3.44Å; P633-S689 PolarHBondContact O-N 3.06Å; S689-G691 PolarHBondContact O-N 3.27Å; S689-G691 VanDerWaalsContact O-N 3.17Å
690S95.4Very high96.2Very high37 Ų3740.6 Ų40.626%0.25924%0.236SC..SBendtrans-68.9-16.2-170.470.40000114.2D688 R692D688-S690 WeakPolarHBondContact OD1-CB 3.41Å; D688-S690 PolarHBondContact OD1-N 3.01Å; D688-S690 PolarHBondContact OD1-OG 2.8Å; D688-S690 PolarHBondContact OD2-OG 2.54Å; S690-R692 PolarHBondContact O-N 2.85Å; S690-R692 VanDerWaalsContact O-N 3.14Å; S690-R692 WeakPolarHBondContact OG-CB 3.49Å; S690-R692 WeakPolarHBondContact OG-CG 2.99Å; S690-R692 PolarHBondContact OG-N 3.31Å
691G91.2Very high96.2Very high69 Ų6938.4 Ų38.471%0.71123%0.228SC*.  trans66.76.4-173.100000114S689S689-G691 PolarHBondContact O-N 3.27Å; S689-G691 VanDerWaalsContact O-N 3.17Å
692R91.1Very high96.3Very high144 Ų14435.7 Ų35.754%0.54321%0.213SC..SBendtrans-69.1164.3175.6-65.2177.3-179.7177.24.2110.5T631 S690 L694 S695T631-R692 PolarHBondContact OG1-NH1 2.95Å; S690-R692 PolarHBondContact O-N 2.85Å; S690-R692 VanDerWaalsContact O-N 3.14Å; S690-R692 WeakPolarHBondContact OG-CB 3.49Å; S690-R692 WeakPolarHBondContact OG-CG 2.99Å; S690-R692 PolarHBondContact OG-N 3.31Å; R692-L694 PolarHBondContact O-N 3.28Å; R692-S695 WeakPolarHBondContact O-CB 3.17Å; R692-S695 PolarHBondContact O-N 2.81Å; R692-S695 PolarHBondContact O-OG 3.2Å
693A87.8Confident96.3Very high85 Ų8534.7 Ų34.770%0.70220%0.202SC*.THydrogen-bonded Turntrans-52-30.9-175.700000114.3N696 R754A693-N696 PolarHBondContact O-OD1 3.27Å; A693-R754 PolarHBondContact O-NH2 3.44Å
694L91Very high96.4Very high67 Ų6728.1 Ų28.135%0.35117%0.173SC..THydrogen-bonded Turntrans-105.42.3-176-54.1-179.7000114.7R692 N696 S697 R754R692-L694 PolarHBondContact O-N 3.28Å; L694-N696 PolarHBondContact O-N 3.04Å; L694-N696 VanDerWaalsContact O-N 3.11Å; L694-S697 WeakPolarHBondContact O-CB 3.01Å; L694-S697 PolarHBondContact O-N 2.92Å; L694-S697 PolarHBondContact O-OG 2.9Å; L694-R754 VanDerWaalsContact CA-NH1 3.33Å; L694-R754 VanDerWaalsContact CD2-CZ 3.43Å
695S95.2Very high96.3Very high14 Ų1427.5 Ų27.510%0.09817%0.171CC..THydrogen-bonded Turntrans-58.5-25.7178.9580000113.5N686 Y687 D688 R692N686-S695 CarbonylContact C-O 3.41Å; N686-S695 WeakPolarHBondContact CB-O 3.22Å; Y687-S695 WeakPolarHBondContact CB-O 3.36Å; Y687-S695 PolarHBondContact N-O 2.85Å; D688-S695 PolarHBondContact N-O 2.8Å; D688-S695 WeakPolarHBondContact O-CB 3.15Å; D688-S695 WeakPolarHBondContact OD1-CA 3.28Å; D688-S695 WeakPolarHBondContact OD1-CB 3.41Å; R692-S695 WeakPolarHBondContact O-CB 3.17Å; R692-S695 PolarHBondContact O-N 2.81Å; R692-S695 PolarHBondContact O-OG 3.2Å
696N96.9Very high96.2Very high48 Ų4827.9 Ų27.926%0.25717%0.173SC..THydrogen-bonded Turntrans-92.211.6179.370.4-21.6000114.8Y684 A693 L694 R754Y684-N696 WeakPolarHBondContact CE2-O 3.46Å; Y684-N696 PolarHBondContact OH-O 3.39Å; A693-N696 PolarHBondContact O-OD1 3.27Å; L694-N696 PolarHBondContact O-N 3.04Å; L694-N696 VanDerWaalsContact O-N 3.11Å; N696-R754 VanDerWaalsContact OD1-CZ 3.25Å; N696-R754 PolarHBondContact OD1-NH1 3.47Å; N696-R754 PolarHBondContact OD1-NH2 3.46Å
697S98.3Very high96.1Very high0 Ų026.5 Ų26.50%017%0.165CC..  trans-59.5142.3173.1-72.90000111.1Y687 L694 M699 R754 D760Y687-S697 PolarHBondContact N-O 3.38Å; L694-S697 WeakPolarHBondContact O-CB 3.01Å; L694-S697 PolarHBondContact O-N 2.92Å; L694-S697 PolarHBondContact O-OG 2.9Å; S697-M699 PolarHBondContact O-N 3.43Å; S697-R754 PolarHBondContact OG-NH1 2.85Å; S697-D760 WeakPolarHBondContact CB-OD2 3.47Å; S697-D760 PolarHBondContact OG-OD2 2.87Å
698I98.6Very high96Very high0 Ų026 Ų260%016%0.163CC..EExtended strand (participates in β ladder)trans-82.6108.7171.5-55.788.2000107.6Y684 V734 L737 N738 M753 P755Y684-I698 HydrophobicContact CD1-CG1 3.99Å; Y684-I698 HydrophobicContact CD2-CG1 3.91Å; Y684-I698 HydrophobicContact CE1-CD1 4.01Å; Y684-I698 HydrophobicContact CE1-CG1 3.71Å; Y684-I698 HydrophobicContact CE2-CB 4.49Å; Y684-I698 HydrophobicContact CE2-CD1 4.21Å; Y684-I698 HydrophobicContact CE2-CG1 3.63Å; Y684-I698 HydrophobicContact CG-CG1 4.1Å; I698-V734 HydrophobicContact CG2-CG2 3.74Å; I698-L737 HydrophobicContact CD1-CD1 3.56Å; I698-L737 HydrophobicContact CG1-CD1 3.95Å; I698-N738 WeakPolarHBondContact CG2-OD1 3.24Å; I698-N738 PolarHBondContact O-ND2 3.18Å; I698-M753 HydrophobicContact CB-CB 4.47Å; I698-M753 VanDerWaalsContact CD1-O 3.22Å; I698-M753 WeakPolarHBondContact CD1-O 3.21Å; I698-M753 PolarHBondContact N-O 2.81Å; I698-M753 PolarHBondContact O-N 3.36Å; I698-P755 HydrophobicContact CD1-CB 4.24Å
699M98.6Very high95.9Very high4 Ų426.2 Ų26.22%0.0217%0.165CC..EExtended strand (participates in β ladder)trans-84.6133172.5-170.7-177.6-174.600110.1Y625 W628 Y636 Y687 S697 D701 Q702 N751Y625-M699 HydrophobicContact CD1-CE 4.35Å; Y625-M699 HydrophobicContact CD2-CE 3.54Å; Y625-M699 HydrophobicContact CE1-CE 4.02Å; Y625-M699 HydrophobicContact CE2-CE 3.18Å; Y625-M699 HydrophobicContact CG-CE 4.14Å; Y625-M699 VanDerWaalsContact CZ-CE 3.45Å; W628-M699 HydrophobicContact CH2-CB 4.41Å; W628-M699 HydrophobicContact CH2-CG 4.17Å; W628-M699 HydrophobicContact CZ3-CE 4.25Å; W628-M699 HydrophobicContact CZ3-CG 3.95Å; W628-M699 HydrophobicContact CZ3-SD 4.46Å; Y636-M699 HydrophobicContact CD2-CE 4.3Å; Y636-M699 HydrophobicContact CG-CE 4.08Å; Y636-M699 HydrophobicContact CG-SD 4.48Å; Y687-M699 HydrophobicContact CD2-CB 4.15Å; Y687-M699 HydrophobicContact CD2-CG 4.4Å; Y687-M699 HydrophobicContact CD2-SD 3.93Å; Y687-M699 HydrophobicContact CE2-SD 3.99Å; S697-M699 PolarHBondContact O-N 3.43Å; M699-D701 HydrophobicContact CE-CB 4.1Å; M699-D701 HydrophobicContact CG-CB 4.5Å; M699-D701 PolarHBondContact O-N 3.43Å; M699-Q702 HydrophobicContact CB-CB 4.23Å; M699-Q702 WeakPolarHBondContact O-CB 3.4Å; M699-Q702 WeakPolarHBondContact O-CG 3.27Å; M699-Q702 PolarHBondContact O-N 2.99Å; M699-Q702 PolarHBondContact O-NE2 3.49Å; M699-N751 CarbonylContact C-O 2.89Å; M699-N751 VanDerWaalsContact CA-O 3.29Å; M699-N751 WeakPolarHBondContact CA-O 3.47Å
700S98.4Very high95.7Very high3 Ų325.3 Ų25.32%0.02116%0.155CC..THydrogen-bonded Turntrans-59.4-33.917760.30000112.2N751S700-N751 PolarHBondContact N-O 2.88Å; S700-N751 WeakPolarHBondContact OG-CA 3.24Å; S700-N751 PolarHBondContact OG-OD1 3.25Å
701D98.3Very high95.7Very high4 Ų423.8 Ų23.82%0.02115%0.145CC..THydrogen-bonded Turntrans-99.915.7-174.8-146.510.3000114Y491 Y625 Y636 M699 C703 A704 V773Y491-D701 PolarHBondContact OH-OD2 2.78Å; Y625-D701 VanDerWaalsContact OH-CB 3.26Å; Y625-D701 WeakPolarHBondContact OH-CB 3.43Å; Y625-D701 PolarHBondContact OH-OD2 2.86Å; Y625-D701 VanDerWaalsContact OH-OD2 3.07Å; Y636-D701 HydrophobicContact CD2-CB 4.29Å; Y636-D701 WeakPolarHBondContact CE2-OD2 3.19Å; M699-D701 HydrophobicContact CE-CB 4.1Å; M699-D701 HydrophobicContact CG-CB 4.5Å; M699-D701 PolarHBondContact O-N 3.43Å; D701-C703 PolarHBondContact O-N 3.35Å; D701-A704 WeakPolarHBondContact O-CB 3.31Å; D701-A704 PolarHBondContact O-N 2.62Å; D701-A704 WeakPolarHBondContact OD1-CB 3.31Å; D701-V773 HydrophobicContact CB-CG1 3.86Å
702Q98.4Very high95.9Very high5 Ų520.5 Ų20.52%0.02311%0.111CC..THydrogen-bonded Turntrans-60.2-11.3-177.573.5-176.2-93.600114.4A635 Y685 M699 V734A635-Q702 HydrophobicContact CB-CB 3.8Å; Y685-Q702 PolarHBondContact O-OE1 2.85Å; M699-Q702 HydrophobicContact CB-CB 4.23Å; M699-Q702 WeakPolarHBondContact O-CB 3.4Å; M699-Q702 WeakPolarHBondContact O-CG 3.27Å; M699-Q702 PolarHBondContact O-N 2.99Å; M699-Q702 PolarHBondContact O-NE2 3.49Å; Q702-V734 HydrophobicContact CG-CG2 4.46Å
703C97.8Very high95.9Very high7 Ų715.4 Ų15.45%0.04710%0.103CC..THydrogen-bonded Turntrans-11418.3179.2-65.80000113.1D701 G705 H706 W707 L731 T780D701-C703 PolarHBondContact O-N 3.35Å; C703-G705 VanDerWaalsContact C-N 3.31Å; C703-G705 PolarHBondContact O-N 2.5Å; C703-H706 PolarHBondContact O-N 3.47Å; C703-H706 VanDerWaalsContact O-N 3.11Å; C703-W707 PolarHBondContact O-N 2.8Å; C703-L731 HydrophobicContact CB-CD2 4.29Å; C703-T780 HydrophobicContact CB-CG2 4.41Å
704A97.9Very high95.9Very high0 Ų011.9 Ų11.90%07%0.073CC..Hα-helixtrans-55.1-41.1-178.600000113.9Y636 D701 W707 F708Y636-A704 HydrophobicContact CD2-CB 3.77Å; Y636-A704 HydrophobicContact CE2-CB 3.72Å; D701-A704 WeakPolarHBondContact O-CB 3.31Å; D701-A704 PolarHBondContact O-N 2.62Å; D701-A704 WeakPolarHBondContact OD1-CB 3.31Å; A704-W707 WeakPolarHBondContact O-CB 3.21Å; A704-W707 PolarHBondContact O-N 3.06Å; A704-F708 PolarHBondContact O-N 2.77Å; A704-F708 VanDerWaalsContact O-N 3.13Å
705G96.8Very high94.9Very high1 Ų116 Ų161%0.019%0.09CC..Hα-helixtrans-62.3-46.4175.500000112.4A643 C703 F708 L709A643-G705 VanDerWaalsContact CB-O 3.32Å; A643-G705 WeakPolarHBondContact CB-O 3.26Å; C703-G705 VanDerWaalsContact C-N 3.31Å; C703-G705 PolarHBondContact O-N 2.5Å; G705-F708 PolarHBondContact O-N 3.39Å; G705-L709 PolarHBondContact O-N 3.07Å
706H96.1Very high93.1Very high9 Ų919 Ų194%0.04210%0.101CC..Hα-helixtrans-63.4-43.7176.9179.176.3000112.2C703 F708 L709 R710 F722 I727 E784C703-H706 PolarHBondContact O-N 3.47Å; C703-H706 VanDerWaalsContact O-N 3.11Å; H706-F708 VanDerWaalsContact C-N 3.26Å; H706-F708 PolarHBondContact O-N 2.89Å; H706-L709 PolarHBondContact O-N 3.01Å; H706-R710 PolarHBondContact O-N 2.69Å; H706-R710 VanDerWaalsContact O-N 3.13Å; H706-F722 HydrophobicContact CB-CD1 4.31Å; H706-F722 HydrophobicContact CB-CD2 4.15Å; H706-F722 HydrophobicContact CB-CE2 4.49Å; H706-F722 HydrophobicContact CB-CG 4.05Å; H706-F722 WeakPolarHBondContact ND1-CB 3.47Å; H706-F722 AromaticContact ND1-CD2 3.97Å; H706-F722 AromaticContact ND1-CG 3.85Å; H706-I727 HydrophobicContact CB-CD1 3.92Å; H706-E784 IonicContact CD2-OE1 3.01Å; H706-E784 IonicContact CE1-OE1 2.8Å; H706-E784 PolarHBondContact CE1-OE1 3.38Å; H706-E784 IonicContact NE2-OE1 2.78Å; H706-E784 PolarHBondContact NE2-OE1 3.07Å
707W96.9Very high91.1Very high1 Ų124.9 Ų24.90%0.00413%0.127CC..Hα-helixtrans-49.9-50.8174169.337.9000111.2F490 Y491 F494 C703 A704 L709 R710 A711 T780 A834F490-W707 HydrophobicContact CD1-CZ3 4.23Å; F490-W707 HydrophobicContact CE1-CE3 4.12Å; F490-W707 AromaticContact CE1-CZ3 3.6Å; F490-W707 HydrophobicContact CE1-CZ3 3.6Å; F490-W707 HydrophobicContact CZ-CZ3 4.31Å; Y491-W707 AromaticContact CD1-CH2 3.87Å; Y491-W707 HydrophobicContact CD1-CH2 3.87Å; Y491-W707 AromaticContact CD1-CZ3 3.71Å; Y491-W707 HydrophobicContact CD1-CZ3 3.71Å; Y491-W707 HydrophobicContact CE1-CH2 4.48Å; Y491-W707 AromaticContact CE1-CZ3 3.87Å; Y491-W707 HydrophobicContact CE1-CZ3 3.87Å; F494-W707 HydrophobicContact CD2-CH2 4.44Å; F494-W707 HydrophobicContact CD2-CZ2 4.2Å; F494-W707 HydrophobicContact CE1-CZ2 4.48Å; F494-W707 AromaticContact CE2-CH2 3.59Å; F494-W707 HydrophobicContact CE2-CH2 3.59Å; F494-W707 AromaticContact CE2-CZ2 3.34Å; F494-W707 HydrophobicContact CE2-CZ2 3.34Å; F494-W707 HydrophobicContact CZ-CH2 4.13Å; F494-W707 AromaticContact CZ-CZ2 3.51Å; F494-W707 HydrophobicContact CZ-CZ2 3.51Å; C703-W707 PolarHBondContact O-N 2.8Å; A704-W707 WeakPolarHBondContact O-CB 3.21Å; A704-W707 PolarHBondContact O-N 3.06Å; W707-L709 PolarHBondContact O-N 2.73Å; W707-R710 PolarHBondContact O-N 3.09Å; W707-A711 PolarHBondContact O-N 3.3Å; W707-T780 HydrophobicContact CB-CG2 3.92Å; W707-T780 WeakPolarHBondContact CB-OG1 3.3Å; W707-A834 HydrophobicContact CZ2-CB 3.6Å
708F96.6Very high89.3Confident0 Ų027.6 Ų27.60%015%0.149CC..Hα-helixtrans-69-34.9-175.3-139.3-88.8000112.7F490 F494 L575 Q576 R579 A704 G705 H706 R710 A711 S712F490-F708 AromaticContact CD2-CD2 3.99Å; F490-F708 HydrophobicContact CD2-CD2 3.99Å; F490-F708 AromaticContact CD2-CE2 3.58Å; F490-F708 HydrophobicContact CD2-CE2 3.58Å; F490-F708 HydrophobicContact CD2-CZ 4.05Å; F490-F708 AromaticContact CE1-CD2 3.97Å; F490-F708 HydrophobicContact CE1-CD2 3.97Å; F490-F708 HydrophobicContact CE1-CE2 4.27Å; F490-F708 HydrophobicContact CE2-CB 4.38Å; F490-F708 HydrophobicContact CE2-CD1 4.27Å; F490-F708 AromaticContact CE2-CD2 3.13Å; F490-F708 HydrophobicContact CE2-CD2 3.13Å; F490-F708 HydrophobicContact CE2-CE1 4.32Å; F490-F708 AromaticContact CE2-CE2 3.2Å; F490-F708 HydrophobicContact CE2-CE2 3.2Å; F490-F708 AromaticContact CE2-CG 3.67Å; F490-F708 HydrophobicContact CE2-CG 3.67Å; F490-F708 AromaticContact CE2-CZ 3.82Å; F490-F708 HydrophobicContact CE2-CZ 3.82Å; F490-F708 HydrophobicContact CG-CE2 4.28Å; F490-F708 HydrophobicContact CZ-CB 4.12Å; F490-F708 AromaticContact CZ-CD2 3.12Å; F490-F708 HydrophobicContact CZ-CD2 3.12Å; F490-F708 AromaticContact CZ-CE2 3.6Å; F490-F708 HydrophobicContact CZ-CE2 3.6Å; F490-F708 AromaticContact CZ-CG 3.78Å; F490-F708 HydrophobicContact CZ-CG 3.78Å; F494-F708 HydrophobicContact CE2-CD2 4.41Å; F494-F708 AromaticContact CE2-CE2 3.78Å; F494-F708 HydrophobicContact CE2-CE2 3.78Å; F494-F708 HydrophobicContact CZ-CD2 4.13Å; F494-F708 AromaticContact CZ-CE2 3.74Å; F494-F708 HydrophobicContact CZ-CE2 3.74Å; F494-F708 HydrophobicContact CZ-CZ 4.37Å; L575-F708 VanDerWaalsContact C-CE1 3.41Å; L575-F708 HydrophobicContact CB-CD1 3.6Å; L575-F708 HydrophobicContact CB-CE1 3.84Å; L575-F708 HydrophobicContact CB-CG 4.24Å; L575-F708 HydrophobicContact CD1-CB 4.36Å; L575-F708 HydrophobicContact CD2-CD1 4.41Å; L575-F708 HydrophobicContact CG-CD1 4.43Å; L575-F708 VanDerWaalsContact O-CE1 3.29Å; L575-F708 WeakPolarHBondContact O-CE1 3.44Å; Q576-F708 HydrophobicContact CB-CZ 4.47Å; Q576-F708 HydrophobicContact CG-CE1 4.24Å; Q576-F708 HydrophobicContact CG-CE2 4.48Å; Q576-F708 HydrophobicContact CG-CZ 3.63Å; R579-F708 HydrophobicContact CB-CD1 4.39Å; R579-F708 HydrophobicContact CB-CE1 3.59Å; R579-F708 HydrophobicContact CB-CZ 4.26Å; R579-F708 HydrophobicContact CG-CE1 4.19Å; A704-F708 PolarHBondContact O-N 2.77Å; A704-F708 VanDerWaalsContact O-N 3.13Å; G705-F708 PolarHBondContact O-N 3.39Å; H706-F708 VanDerWaalsContact C-N 3.26Å; H706-F708 PolarHBondContact O-N 2.89Å; F708-R710 VanDerWaalsContact C-N 3.33Å; F708-R710 PolarHBondContact O-N 3.19Å; F708-A711 WeakPolarHBondContact O-CB 3.32Å; F708-A711 PolarHBondContact O-N 3.49Å; F708-S712 WeakPolarHBondContact O-CB 3.42Å; F708-S712 PolarHBondContact O-N 2.77Å; F708-S712 PolarHBondContact O-OG 2.77Å
709L95.3Very high87.7Confident13 Ų1329.8 Ų29.87%0.06816%0.158CC..Hα-helixtrans-59-44.3171.8-67.4-178.8000112.2A643 C646 V647 G705 H706 W707 A711 S712 G713 L714 F722A643-L709 HydrophobicContact CB-CD1 4.1Å; A643-L709 HydrophobicContact CB-CD2 3.94Å; A643-L709 HydrophobicContact CB-CG 3.77Å; A643-L709 WeakPolarHBondContact O-CD2 3.28Å; C646-L709 HydrophobicContact CB-CD1 4.25Å; C646-L709 HydrophobicContact CB-CD2 3.84Å; V647-L709 HydrophobicContact CG1-CD2 3.8Å; G705-L709 PolarHBondContact O-N 3.07Å; H706-L709 PolarHBondContact O-N 3.01Å; W707-L709 PolarHBondContact O-N 2.73Å; L709-A711 VanDerWaalsContact C-N 3.34Å; L709-S712 CarbonylContact O-C 3.57Å; L709-S712 PolarHBondContact O-N 2.91Å; L709-G713 PolarHBondContact O-N 3.41Å; L709-L714 HydrophobicContact CB-CB 4.41Å; L709-L714 HydrophobicContact CD2-CD1 3.74Å; L709-L714 PolarHBondContact O-N 3.5Å; L709-F722 HydrophobicContact CD1-CD2 3.69Å; L709-F722 HydrophobicContact CD1-CE2 3.62Å
710R93.9Very high86.3Confident20 Ų2038.6 Ų38.68%0.07520%0.199CC..Hα-helixtrans-65.1-39.9177.1-62.4-50-52-79.2-5.6111.4H706 W707 F708 S712 G713 H783 E784H706-R710 PolarHBondContact O-N 2.69Å; H706-R710 VanDerWaalsContact O-N 3.13Å; W707-R710 PolarHBondContact O-N 3.09Å; F708-R710 VanDerWaalsContact C-N 3.33Å; F708-R710 PolarHBondContact O-N 3.19Å; R710-S712 VanDerWaalsContact C-N 3.27Å; R710-S712 PolarHBondContact O-N 3.19Å; R710-G713 PolarHBondContact O-N 2.76Å; R710-H783 HydrophobicContact CB-CB 3.94Å; R710-H783 HydrophobicContact CG-CB 4.24Å; R710-H783 PolarHBondContact NH1-O 3.02Å; R710-E784 IonicContact CZ-OE1 2.84Å; R710-E784 IonicContact NH1-OE1 3.19Å; R710-E784 PolarHBondContact NH1-OE1 2.87Å; R710-E784 IonicContact NH1-OE2 3.19Å
711A95.4Very high85.4Confident5 Ų538.7 Ų38.74%0.04120%0.2CC..Hα-helixtrans-64.1-29.7174.400000113.3F494 W707 F708 L709 G713 L837F494-A711 HydrophobicContact CE1-CB 3.74Å; F494-A711 HydrophobicContact CZ-CB 3.94Å; W707-A711 PolarHBondContact O-N 3.3Å; F708-A711 WeakPolarHBondContact O-CB 3.32Å; F708-A711 PolarHBondContact O-N 3.49Å; L709-A711 VanDerWaalsContact C-N 3.34Å; A711-G713 VanDerWaalsContact C-N 3.28Å; A711-G713 PolarHBondContact O-N 2.89Å; A711-L837 HydrophobicContact CB-CD2 4.08Å
712S95Very high84.9Confident0 Ų039.3 Ų39.30%020%0.203CC..THydrogen-bonded Turntrans-86.711.8175.5-55.80000114R579 H582 F708 L709 R710 L714R579-S712 WeakPolarHBondContact CA-OG 3.48Å; R579-S712 WeakPolarHBondContact CB-OG 3.04Å; H582-S712 VanDerWaalsContact CD2-C 3.49Å; H582-S712 PolarHBondContact CD2-O 2.91Å; H582-S712 PolarHBondContact ND1-O 3.25Å; F708-S712 WeakPolarHBondContact O-CB 3.42Å; F708-S712 PolarHBondContact O-N 2.77Å; F708-S712 PolarHBondContact O-OG 2.77Å; L709-S712 CarbonylContact O-C 3.57Å; L709-S712 PolarHBondContact O-N 2.91Å; R710-S712 VanDerWaalsContact C-N 3.27Å; R710-S712 PolarHBondContact O-N 3.19Å; S712-L714 VanDerWaalsContact C-N 3.26Å; S712-L714 PolarHBondContact O-N 3.02Å
713G90.9Very high84.5Confident37 Ų3741.7 Ų41.738%0.38122%0.218SC..THydrogen-bonded Turntrans67.221.8178.200000114.6L709 R710 A711L709-G713 PolarHBondContact O-N 3.41Å; R710-G713 PolarHBondContact O-N 2.76Å; A711-G713 VanDerWaalsContact C-N 3.28Å; A711-G713 PolarHBondContact O-N 2.89Å
714L88.8Confident84.1Confident12 Ų1245.2 Ų45.26%0.06323%0.233CC..  trans-85.3120.8171.7-69.8175000109.9Y578 V647 K650 L709 S712 Y719Y578-L714 HydrophobicContact CD1-CD1 4.33Å; Y578-L714 HydrophobicContact CE1-CD1 3.78Å; Y578-L714 HydrophobicContact CE1-CD2 4.22Å; Y578-L714 HydrophobicContact CE1-CG 3.82Å; V647-L714 HydrophobicContact CG1-CD1 3.72Å; K650-L714 HydrophobicContact CB-CD2 4.47Å; K650-L714 HydrophobicContact CD-CD2 4.31Å; K650-L714 HydrophobicContact CG-CD2 4.11Å; L709-L714 HydrophobicContact CB-CB 4.41Å; L709-L714 HydrophobicContact CD2-CD1 3.74Å; L709-L714 PolarHBondContact O-N 3.5Å; S712-L714 VanDerWaalsContact C-N 3.26Å; S712-L714 PolarHBondContact O-N 3.02Å; L714-Y719 HydrophobicContact CD1-CE2 4.49Å; L714-Y719 HydrophobicContact CD2-CE2 4.32Å
715E69.2Low83.9Confident152 Ų15251.4 Ų51.471%0.7126%0.262SS*.  trans-73.6161.3-174.5-66.9-174.7177.900113.3E717 A718E715-E717 PolarHBondContact O-N 3.26Å; E715-A718 PolarHBondContact O-N 3.43Å
716K57Low83.8Confident78 Ų7853.3 Ų53.334%0.33927%0.27SS..THydrogen-bonded Turntrans-56.7-20-172.1-68.7171.5177.3163.20115.1K724K716-K724 HydrophobicContact CD-CD 4.04Å
717E55.6Low83.8Confident172 Ų17253 Ų5380%0.80427%0.268SS*.THydrogen-bonded Turntrans-119.7-6-168.3-69.7150.7-155.900113.3E715 Y719E715-E717 PolarHBondContact O-N 3.26Å; E717-Y719 VanDerWaalsContact C-N 3.27Å; E717-Y719 PolarHBondContact O-N 2.79Å
718A59.4Low83.8Confident56 Ų5657.4 Ų57.446%0.46329%0.285SS..SBendtrans-66.6-30.8-174.600000112.5E715E715-A718 PolarHBondContact O-N 3.43Å
719Y64.7Low83.9Confident47 Ų4763.9 Ų63.918%0.18431%0.309CS..  trans-144.1129.4-176.9-57.7-75.2000110.3C646 C649 K650 L668 L714 E717 A721C646-Y719 HydrophobicContact CB-CD2 3.79Å; C646-Y719 HydrophobicContact CB-CE2 4.26Å; C646-Y719 HydrophobicContact CB-CG 3.97Å; C646-Y719 WeakPolarHBondContact SG-CB 3.21Å; C649-Y719 HydrophobicContact CB-CE1 3.73Å; K650-Y719 PolarHBondContact N-OH 2.91Å; L668-Y719 HydrophobicContact CD2-CD1 3.65Å; L668-Y719 HydrophobicContact CD2-CE1 4.49Å; L668-Y719 HydrophobicContact CD2-CG 4.17Å; L714-Y719 HydrophobicContact CD1-CE2 4.49Å; L714-Y719 HydrophobicContact CD2-CE2 4.32Å; E717-Y719 VanDerWaalsContact C-N 3.27Å; E717-Y719 PolarHBondContact O-N 2.79Å; Y719-A721 PolarHBondContact O-N 2.9Å
720Q69.1Low84Confident188 Ų18863.3 Ų63.388%0.87931%0.306SS*.THydrogen-bonded Turntrans-74.514.2-174.5-67.1-172.4-4.300114.8F722Q720-F722 PolarHBondContact O-N 3.2Å
721A79.6Confident84.2Confident5 Ų562.4 Ų62.44%0.04130%0.303CS..THydrogen-bonded Turntrans-68.4-33.3-175.200000114.1L642 L668 S672 Y719L642-A721 HydrophobicContact CB-CB 4.17Å; L642-A721 HydrophobicContact CD1-CB 4.37Å; L668-A721 HydrophobicContact CD1-CB 4Å; S672-A721 WeakPolarHBondContact OG-CA 3.24Å; S672-A721 WeakPolarHBondContact OG-CB 3.36Å; Y719-A721 PolarHBondContact O-N 2.9Å
722F88.2Confident84.4Confident18 Ų1866 Ų668%0.07932%0.317CS..SBendtrans-129.787.6-173.6-60-64.3000111.3G639 L642 A643 F675 H706 L709 Q720 K724 I727G639-F722 WeakPolarHBondContact O-CZ 3.41Å; L642-F722 HydrophobicContact CB-CE2 4.38Å; L642-F722 HydrophobicContact CB-CZ 3.94Å; A643-F722 HydrophobicContact CB-CE2 4.31Å; F675-F722 HydrophobicContact CE1-CE1 4.42Å; H706-F722 HydrophobicContact CB-CD1 4.31Å; H706-F722 HydrophobicContact CB-CD2 4.15Å; H706-F722 HydrophobicContact CB-CE2 4.49Å; H706-F722 HydrophobicContact CB-CG 4.05Å; H706-F722 WeakPolarHBondContact ND1-CB 3.47Å; H706-F722 AromaticContact ND1-CD2 3.97Å; H706-F722 AromaticContact ND1-CG 3.85Å; L709-F722 HydrophobicContact CD1-CD2 3.69Å; L709-F722 HydrophobicContact CD1-CE2 3.62Å; Q720-F722 PolarHBondContact O-N 3.2Å; F722-K724 PolarHBondContact O-N 2.84Å; F722-K724 VanDerWaalsContact O-N 3.13Å; F722-I727 HydrophobicContact CB-CD1 4.01Å; F722-I727 HydrophobicContact CB-CG1 3.89Å; F722-I727 HydrophobicContact CD1-CD1 4.03Å; F722-I727 HydrophobicContact CG-CD1 4.31Å
723P91.1Very high84.6Confident54 Ų5466.8 Ų66.835%0.35132%0.323SS..  trans-58.2121.3176.7-24.734.7000110.9E725 K726 I727P723-E725 VanDerWaalsContact C-N 3.26Å; P723-E725 PolarHBondContact O-N 3.21Å; P723-E725 VanDerWaalsContact O-N 3.14Å; P723-K726 HydrophobicContact CB-CB 4.31Å; P723-K726 HydrophobicContact CB-CD 4.23Å; P723-K726 HydrophobicContact CB-CG 4.1Å; P723-K726 HydrophobicContact CG-CD 4.17Å; P723-K726 WeakPolarHBondContact O-CA 3.16Å; P723-K726 WeakPolarHBondContact O-CB 3.4Å; P723-K726 PolarHBondContact O-N 3.18Å; P723-I727 PolarHBondContact O-N 2.67Å
724K89.2Confident84.9Confident82 Ų8265 Ų6536%0.35731%0.305SS..Hα-helixtrans-48.8-45-175.3-174.8-171.7-177.1-176.70113.4K716 F722 K726 I727 R728K716-K724 HydrophobicContact CD-CD 4.04Å; F722-K724 PolarHBondContact O-N 2.84Å; F722-K724 VanDerWaalsContact O-N 3.13Å; K724-K726 VanDerWaalsContact C-N 3.31Å; K724-K726 PolarHBondContact O-N 2.83Å; K724-I727 PolarHBondContact O-N 2.94Å; K724-R728 WeakPolarHBondContact O-CG 3.35Å; K724-R728 PolarHBondContact O-N 3.39Å
725E92.7Very high85.4Confident130 Ų13065.6 Ų65.661%0.60731%0.307SS*.Hα-helixtrans-63.5-36.2179.7-65.6-54.1132.700112.7P723 R729P723-E725 VanDerWaalsContact C-N 3.26Å; P723-E725 PolarHBondContact O-N 3.21Å; P723-E725 VanDerWaalsContact O-N 3.14Å; E725-R729 WeakPolarHBondContact O-CB 3.47Å; E725-R729 PolarHBondContact O-N 3.38Å; E725-R729 VanDerWaalsContact O-N 3.12Å
726K95.8Very high86.8Confident41 Ų4161.4 Ų61.418%0.17829%0.29CS..Hα-helixtrans-70.8-43.3176.6-64.8-170179-1660111.1D676 W680 Y685 P723 K724 R729 A730D676-K726 WeakPolarHBondContact OD1-CD 3.09Å; D676-K726 IonicContact OD1-NZ 2.9Å; D676-K726 PolarHBondContact OD1-NZ 2.85Å; D676-K726 IonicContact OD2-NZ 2.63Å; D676-K726 PolarHBondContact OD2-NZ 3.18Å; W680-K726 VanDerWaalsContact CD1-NZ 3.29Å; W680-K726 HydrophobicContact CD2-CB 4.48Å; W680-K726 HydrophobicContact CD2-CD 3.69Å; W680-K726 HydrophobicContact CD2-CG 4.15Å; W680-K726 HydrophobicContact CE3-CB 4.1Å; W680-K726 HydrophobicContact CE3-CD 4.06Å; W680-K726 HydrophobicContact CE3-CG 4.27Å; W680-K726 HydrophobicContact CG-CD 4.02Å; W680-K726 HydrophobicContact CH2-CB 3.76Å; W680-K726 HydrophobicContact CH2-CD 4.47Å; W680-K726 HydrophobicContact CH2-CG 3.87Å; W680-K726 HydrophobicContact CZ2-CB 4.17Å; W680-K726 HydrophobicContact CZ2-CD 4.14Å; W680-K726 HydrophobicContact CZ2-CG 3.74Å; W680-K726 HydrophobicContact CZ3-CB 3.72Å; W680-K726 HydrophobicContact CZ3-CD 4.44Å; W680-K726 HydrophobicContact CZ3-CG 4.13Å; Y685-K726 WeakPolarHBondContact OH-CB 3.33Å; P723-K726 HydrophobicContact CB-CB 4.31Å; P723-K726 HydrophobicContact CB-CD 4.23Å; P723-K726 HydrophobicContact CB-CG 4.1Å; P723-K726 HydrophobicContact CG-CD 4.17Å; P723-K726 WeakPolarHBondContact O-CA 3.16Å; P723-K726 WeakPolarHBondContact O-CB 3.4Å; P723-K726 PolarHBondContact O-N 3.18Å; K724-K726 VanDerWaalsContact C-N 3.31Å; K724-K726 PolarHBondContact O-N 2.83Å; K726-R729 PolarHBondContact O-N 2.58Å; K726-A730 WeakPolarHBondContact O-CB 3.26Å; K726-A730 PolarHBondContact O-N 2.73Å
727I95.8Very high88.8Confident1 Ų159.3 Ų59.31%0.00528%0.282CS..Hα-helixtrans-59.4-51175.3-66.1-63.1000111.3Y685 H706 F722 P723 K724 R729 A730 L731 E784Y685-I727 HydrophobicContact CE2-CD1 4.25Å; H706-I727 HydrophobicContact CB-CD1 3.92Å; F722-I727 HydrophobicContact CB-CD1 4.01Å; F722-I727 HydrophobicContact CB-CG1 3.89Å; F722-I727 HydrophobicContact CD1-CD1 4.03Å; F722-I727 HydrophobicContact CG-CD1 4.31Å; P723-I727 PolarHBondContact O-N 2.67Å; K724-I727 PolarHBondContact O-N 2.94Å; I727-R729 VanDerWaalsContact C-N 3.26Å; I727-R729 PolarHBondContact O-N 2.9Å; I727-A730 PolarHBondContact O-N 2.57Å; I727-A730 VanDerWaalsContact O-N 3.16Å; I727-L731 HydrophobicContact CG2-CD1 3.78Å; I727-L731 HydrophobicContact CG2-CG 4.24Å; I727-L731 WeakPolarHBondContact O-CG 3.24Å; I727-L731 PolarHBondContact O-N 2.79Å; I727-E784 HydrophobicContact CG2-CG 4.1Å
728R96.1Very high90.9Very high95 Ų9551.1 Ų51.136%0.35824%0.244SC..Hα-helixtrans-60.8-37.6179.7-68.8-175.484.9178.78.6112K724 K732 E784K724-R728 WeakPolarHBondContact O-CG 3.35Å; K724-R728 PolarHBondContact O-N 3.39Å; R728-K732 VanDerWaalsContact O-CB 3.31Å; R728-K732 WeakPolarHBondContact O-CB 3.36Å; R728-K732 PolarHBondContact O-N 3.44Å; R728-E784 HydrophobicContact CG-CB 4.29Å; R728-E784 PolarHBondContact NE-O 3.18Å
729R98.1Very high92.7Very high136 Ų13648.5 Ų48.551%0.51322%0.222SC..Hα-helixtrans-69.4-39.1176.3-165.4-176.3-67.6-154.7-9.3112.6W680 G682 K683 E725 K726 I727 K732 S733W680-R729 HydrophobicContact CH2-CB 4.2Å; W680-R729 HydrophobicContact CH2-CG 4.47Å; G682-R729 WeakPolarHBondContact O-CD 3.32Å; G682-R729 PolarHBondContact O-NH1 3.45Å; K683-R729 CarbonylContact O-C 3.58Å; K683-R729 WeakPolarHBondContact O-CD 3.35Å; K683-R729 WeakPolarHBondContact O-CG 3.4Å; E725-R729 WeakPolarHBondContact O-CB 3.47Å; E725-R729 PolarHBondContact O-N 3.38Å; E725-R729 VanDerWaalsContact O-N 3.12Å; K726-R729 PolarHBondContact O-N 2.58Å; I727-R729 VanDerWaalsContact C-N 3.26Å; I727-R729 PolarHBondContact O-N 2.9Å; R729-K732 PolarHBondContact O-N 3.01Å; R729-S733 PolarHBondContact O-N 3.27Å; R729-S733 PolarHBondContact O-OG 3.23Å
730A98.5Very high94.3Very high0 Ų049.6 Ų49.60%023%0.229CC..Hα-helixtrans-62.5-50.4173.800000111K683 Y685 K726 I727 K732 S733 V734K683-A730 PolarHBondContact O-N 3.3Å; Y685-A730 HydrophobicContact CD2-CB 4.21Å; Y685-A730 HydrophobicContact CE2-CB 4.45Å; K726-A730 WeakPolarHBondContact O-CB 3.26Å; K726-A730 PolarHBondContact O-N 2.73Å; I727-A730 PolarHBondContact O-N 2.57Å; I727-A730 VanDerWaalsContact O-N 3.16Å; A730-K732 VanDerWaalsContact C-N 3.32Å; A730-K732 PolarHBondContact O-N 3.4Å; A730-S733 WeakPolarHBondContact O-CA 3.15Å; A730-S733 WeakPolarHBondContact O-CB 3.33Å; A730-S733 PolarHBondContact O-N 2.94Å; A730-V734 WeakPolarHBondContact O-CG2 3.38Å; A730-V734 PolarHBondContact O-N 2.97Å
731L98.8Very high95.6Very high1 Ų143.7 Ų43.71%0.00521%0.209CC..Hα-helixtrans-59.3-40.7176.3-68.1173.1000112.3C703 I727 S733 V734 F735 L777 T780 M781 E784 M786C703-L731 HydrophobicContact CB-CD2 4.29Å; I727-L731 HydrophobicContact CG2-CD1 3.78Å; I727-L731 HydrophobicContact CG2-CG 4.24Å; I727-L731 WeakPolarHBondContact O-CG 3.24Å; I727-L731 PolarHBondContact O-N 2.79Å; L731-S733 VanDerWaalsContact C-N 3.33Å; L731-S733 PolarHBondContact O-N 2.87Å; L731-V734 PolarHBondContact O-N 3.36Å; L731-F735 PolarHBondContact O-N 3Å; L731-L777 HydrophobicContact CD2-CD1 3.83Å; L731-T780 HydrophobicContact CD1-CG2 4.09Å; L731-T780 HydrophobicContact CD2-CG2 3.9Å; L731-M781 HydrophobicContact CD2-CG 4.39Å; L731-E784 HydrophobicContact CD1-CB 4.1Å; L731-E784 HydrophobicContact CD1-CG 3.94Å; L731-M786 HydrophobicContact CB-CE 4.3Å; L731-M786 HydrophobicContact CB-SD 3.91Å; L731-M786 HydrophobicContact CD1-SD 4.35Å
732K98.7Very high96.5Very high80 Ų8043.6 Ų43.635%0.34821%0.208SC..Hα-helixtrans-63.8-39174.6-171.860.6166.976.20112R728 R729 A730 F735 D736 M786R728-K732 VanDerWaalsContact O-CB 3.31Å; R728-K732 WeakPolarHBondContact O-CB 3.36Å; R728-K732 PolarHBondContact O-N 3.44Å; R729-K732 PolarHBondContact O-N 3.01Å; A730-K732 VanDerWaalsContact C-N 3.32Å; A730-K732 PolarHBondContact O-N 3.4Å; K732-F735 PolarHBondContact O-N 3.13Å; K732-D736 IonicContact NZ-OD1 3.52Å; K732-D736 PolarHBondContact NZ-OD1 2.91Å; K732-D736 IonicContact NZ-OD2 3.32Å; K732-D736 PolarHBondContact NZ-OD2 3.3Å; K732-D736 WeakPolarHBondContact O-CB 3.3Å; K732-D736 VanDerWaalsContact O-CG 3.28Å; K732-D736 PolarHBondContact O-N 2.99Å; K732-M786 HydrophobicContact CB-CE 4.25Å; K732-M786 HydrophobicContact CD-CE 4.17Å
733S98.7Very high96.7Very high18 Ų1844.4 Ų44.413%0.12622%0.215CC..Hα-helixtrans-64-42.6175.3-55.80000111.4R729 A730 L731 D736 L737R729-S733 PolarHBondContact O-N 3.27Å; R729-S733 PolarHBondContact O-OG 3.23Å; A730-S733 WeakPolarHBondContact O-CA 3.15Å; A730-S733 WeakPolarHBondContact O-CB 3.33Å; A730-S733 PolarHBondContact O-N 2.94Å; L731-S733 VanDerWaalsContact C-N 3.33Å; L731-S733 PolarHBondContact O-N 2.87Å; S733-D736 PolarHBondContact O-N 3.47Å; S733-L737 WeakPolarHBondContact O-CB 3.44Å; S733-L737 PolarHBondContact O-N 3.37Å
734V98.8Very high96.9Very high0 Ų048.5 Ų48.50%023%0.23CC..Hα-helixtrans-61-45.6173.6175.10000110.9I698 Q702 A730 L731 N738 V739 L777I698-V734 HydrophobicContact CG2-CG2 3.74Å; Q702-V734 HydrophobicContact CG-CG2 4.46Å; A730-V734 WeakPolarHBondContact O-CG2 3.38Å; A730-V734 PolarHBondContact O-N 2.97Å; L731-V734 PolarHBondContact O-N 3.36Å; V734-N738 HydrophobicContact CG1-CB 4.01Å; V734-N738 WeakPolarHBondContact O-CA 3.48Å; V734-N738 VanDerWaalsContact O-CB 3.27Å; V734-N738 WeakPolarHBondContact O-CB 3.19Å; V734-N738 PolarHBondContact O-N 2.94Å; V734-V739 PolarHBondContact O-N 2.87Å; V734-L777 HydrophobicContact CG1-CD1 4.06Å; V734-L777 HydrophobicContact CG1-CD2 3.52Å; V734-L777 HydrophobicContact CG1-CG 4.42Å
735F98.8Very high97.2Very high24 Ų2444.6 Ų44.611%0.10521%0.213CC..Iπ-helixtrans-61.9-48.3177.9-177.1-106.9000112.2L731 K732 L737 V739 M740 M781 E789 R792L731-F735 PolarHBondContact O-N 3Å; K732-F735 PolarHBondContact O-N 3.13Å; F735-L737 VanDerWaalsContact C-N 3.34Å; F735-L737 PolarHBondContact O-N 3.45Å; F735-V739 HydrophobicContact CD2-CB 4.15Å; F735-V739 HydrophobicContact CD2-CG1 4.25Å; F735-V739 HydrophobicContact CD2-CG2 4.37Å; F735-V739 HydrophobicContact CE2-CG1 4.18Å; F735-V739 VanDerWaalsContact O-CB 3.32Å; F735-V739 WeakPolarHBondContact O-CB 3.44Å; F735-V739 PolarHBondContact O-N 2.84Å; F735-M740 HydrophobicContact CD1-CG 4.05Å; F735-M740 HydrophobicContact CE1-CG 3.62Å; F735-M740 HydrophobicContact CE1-SD 4.18Å; F735-M740 HydrophobicContact CE2-CG 4.21Å; F735-M740 HydrophobicContact CE2-SD 4.2Å; F735-M740 HydrophobicContact CZ-CG 3.72Å; F735-M740 HydrophobicContact CZ-SD 3.7Å; F735-M740 WeakPolarHBondContact O-CG 3.46Å; F735-M740 PolarHBondContact O-N 3.35Å; F735-M781 HydrophobicContact CB-CE 3.75Å; F735-M781 HydrophobicContact CD2-CE 4.29Å; F735-M781 HydrophobicContact CD2-SD 4.46Å; F735-M781 HydrophobicContact CG-CE 4.48Å; F735-E789 HydrophobicContact CD1-CB 4.21Å; F735-E789 HydrophobicContact CD1-CG 3.64Å; F735-E789 HydrophobicContact CD2-CB 3.6Å; F735-E789 HydrophobicContact CD2-CG 3.99Å; F735-E789 HydrophobicContact CE1-CB 4.33Å; F735-E789 HydrophobicContact CE1-CG 3.7Å; F735-E789 HydrophobicContact CE2-CB 3.75Å; F735-E789 HydrophobicContact CE2-CG 4.06Å; F735-E789 WeakPolarHBondContact CE2-O 3.45Å; F735-E789 HydrophobicContact CG-CB 3.84Å; F735-E789 HydrophobicContact CG-CG 3.78Å; F735-E789 HydrophobicContact CZ-CB 4.11Å; F735-E789 HydrophobicContact CZ-CG 3.91Å; F735-R792 HydrophobicContact CE2-CB 4.12Å; F735-R792 HydrophobicContact CE2-CG 4.12Å; F735-R792 HydrophobicContact CZ-CB 4.37Å; F735-R792 HydrophobicContact CZ-CG 4.2Å
736D98.7Very high97.2Very high64 Ų6440.7 Ų40.734%0.34219%0.194SC..Iπ-helixtrans-67.2-36.3-176.5-69.5-18.8000112.5K732 S733 S741K732-D736 IonicContact NZ-OD1 3.52Å; K732-D736 PolarHBondContact NZ-OD1 2.91Å; K732-D736 IonicContact NZ-OD2 3.32Å; K732-D736 PolarHBondContact NZ-OD2 3.3Å; K732-D736 WeakPolarHBondContact O-CB 3.3Å; K732-D736 VanDerWaalsContact O-CG 3.28Å; K732-D736 PolarHBondContact O-N 2.99Å; S733-D736 PolarHBondContact O-N 3.47Å; D736-S741 PolarHBondContact O-N 2.82Å; D736-S741 PolarHBondContact O-OG 2.84Å
737L98.6Very high97.2Very high34 Ų3439.2 Ų39.218%0.17819%0.189CC..Iπ-helixtrans-97.9-67-174.7-62.1174.6000111.5I698 S733 F735 V739 S741 M753I698-L737 HydrophobicContact CD1-CD1 3.56Å; I698-L737 HydrophobicContact CG1-CD1 3.95Å; S733-L737 WeakPolarHBondContact O-CB 3.44Å; S733-L737 PolarHBondContact O-N 3.37Å; F735-L737 VanDerWaalsContact C-N 3.34Å; F735-L737 PolarHBondContact O-N 3.45Å; L737-V739 PolarHBondContact O-N 3.49Å; L737-S741 VanDerWaalsContact O-CB 3.24Å; L737-S741 WeakPolarHBondContact O-CB 3.46Å; L737-S741 PolarHBondContact O-N 3.12Å; L737-M753 HydrophobicContact CB-CB 4.48Å; L737-M753 HydrophobicContact CB-CG 3.73Å; L737-M753 WeakPolarHBondContact O-CE 3.29Å
738N98.7Very high97.3Very high0 Ų039.2 Ų39.20%019%0.188CC..Iπ-helixtrans-66.1-24.3-174.1-58.563.8000113.8I698 V734 F742 A749 V750 M753I698-N738 WeakPolarHBondContact CG2-OD1 3.24Å; I698-N738 PolarHBondContact O-ND2 3.18Å; V734-N738 HydrophobicContact CG1-CB 4.01Å; V734-N738 WeakPolarHBondContact O-CA 3.48Å; V734-N738 VanDerWaalsContact O-CB 3.27Å; V734-N738 WeakPolarHBondContact O-CB 3.19Å; V734-N738 PolarHBondContact O-N 2.94Å; N738-F742 VanDerWaalsContact O-CB 3.26Å; N738-F742 WeakPolarHBondContact O-CB 3.32Å; N738-A749 HydrophobicContact CB-CB 4.42Å; N738-A749 WeakPolarHBondContact O-CA 3.37Å; N738-V750 HydrophobicContact CB-CG1 4.4Å; N738-V750 WeakPolarHBondContact CB-O 3.44Å; N738-V750 PolarHBondContact ND2-O 2.73Å; N738-V750 PolarHBondContact O-N 2.79Å; N738-M753 HydrophobicContact CB-CB 4.42Å
739V98.6Very high97.4Very high0 Ų034.7 Ų34.70%017%0.172CC..Iπ-helixtrans-103.8-66.5178.4-176.70000110.7V734 F735 L737 S741 F742 G745 A749 T793V734-V739 PolarHBondContact O-N 2.87Å; F735-V739 HydrophobicContact CD2-CB 4.15Å; F735-V739 HydrophobicContact CD2-CG1 4.25Å; F735-V739 HydrophobicContact CD2-CG2 4.37Å; F735-V739 HydrophobicContact CE2-CG1 4.18Å; F735-V739 VanDerWaalsContact O-CB 3.32Å; F735-V739 WeakPolarHBondContact O-CB 3.44Å; F735-V739 PolarHBondContact O-N 2.84Å; L737-V739 PolarHBondContact O-N 3.49Å; V739-S741 PolarHBondContact O-N 3.07Å; V739-F742 CarbonylContact O-C 3.48Å; V739-F742 PolarHBondContact O-N 3.13Å; V739-F742 VanDerWaalsContact O-N 3.12Å; V739-G745 WeakPolarHBondContact O-CA 3.47Å; V739-G745 PolarHBondContact O-N 3.28Å; V739-A749 HydrophobicContact CG2-CB 3.64Å; V739-T793 HydrophobicContact CG2-CG2 3.77Å
740M98.3Very high97.4Very high70 Ų7028.2 Ų28.235%0.34515%0.147SC..Iπ-helixtrans-71.9-31.7-169.7-66.3-55.2-5700113.4F735 F742 E744 R792F735-M740 HydrophobicContact CD1-CG 4.05Å; F735-M740 HydrophobicContact CE1-CG 3.62Å; F735-M740 HydrophobicContact CE1-SD 4.18Å; F735-M740 HydrophobicContact CE2-CG 4.21Å; F735-M740 HydrophobicContact CE2-SD 4.2Å; F735-M740 HydrophobicContact CZ-CG 3.72Å; F735-M740 HydrophobicContact CZ-SD 3.7Å; F735-M740 WeakPolarHBondContact O-CG 3.46Å; F735-M740 PolarHBondContact O-N 3.35Å; M740-F742 VanDerWaalsContact C-N 3.3Å; M740-E744 VanDerWaalsContact O-CA 3.28Å; M740-E744 WeakPolarHBondContact O-CA 3.18Å; M740-R792 HydrophobicContact SD-CG 4.35Å
741S97.1Very high97.4Very high64 Ų6428.2 Ų28.245%0.44815%0.147SC..THydrogen-bonded Turntrans-82.4-9.2173.8-51.80000112.8D736 L737 V739D736-S741 PolarHBondContact O-N 2.82Å; D736-S741 PolarHBondContact O-OG 2.84Å; L737-S741 VanDerWaalsContact O-CB 3.24Å; L737-S741 WeakPolarHBondContact O-CB 3.46Å; L737-S741 PolarHBondContact O-N 3.12Å; V739-S741 PolarHBondContact O-N 3.07Å
742F96.4Very high97.4Very high4 Ų428.2 Ų28.22%0.01815%0.147CC..SBendtrans-101100.9175.9-174.3-106.1000110.8N738 V739 M740 E744 G745 M747 V750 M753 P759 V769 E817N738-F742 VanDerWaalsContact O-CB 3.26Å; N738-F742 WeakPolarHBondContact O-CB 3.32Å; V739-F742 CarbonylContact O-C 3.48Å; V739-F742 PolarHBondContact O-N 3.13Å; V739-F742 VanDerWaalsContact O-N 3.12Å; M740-F742 VanDerWaalsContact C-N 3.3Å; F742-E744 PolarHBondContact O-N 3.06Å; F742-E744 VanDerWaalsContact O-N 3.15Å; F742-G745 PolarHBondContact O-N 2.91Å; F742-G745 VanDerWaalsContact O-N 3.14Å; F742-M747 HydrophobicContact CD1-CB 4.07Å; F742-M747 HydrophobicContact CE1-CB 3.7Å; F742-V750 HydrophobicContact CB-CG1 4.09Å; F742-V750 HydrophobicContact CD1-CB 4.13Å; F742-V750 HydrophobicContact CD2-CB 3.83Å; F742-V750 HydrophobicContact CD2-CG1 3.87Å; F742-V750 HydrophobicContact CD2-CG2 4.4Å; F742-V750 HydrophobicContact CE1-CB 4.28Å; F742-V750 HydrophobicContact CE2-CB 3.99Å; F742-V750 HydrophobicContact CE2-CG1 4.47Å; F742-V750 HydrophobicContact CE2-CG2 4.18Å; F742-V750 HydrophobicContact CG-CB 3.89Å; F742-V750 HydrophobicContact CG-CG1 3.92Å; F742-V750 HydrophobicContact CZ-CB 4.21Å; F742-V750 HydrophobicContact CZ-CG2 4.49Å; F742-M753 HydrophobicContact CB-CE 4.07Å; F742-P759 HydrophobicContact CD2-CG 4.19Å; F742-P759 HydrophobicContact CE2-CG 4.42Å; F742-V769 HydrophobicContact CD1-CG2 4.2Å; F742-V769 HydrophobicContact CE1-CG2 3.42Å; F742-V769 VanDerWaalsContact CE1-CG2 3.42Å; F742-V769 HydrophobicContact CZ-CG2 3.99Å; F742-E817 HydrophobicContact CE2-CB 4.03Å; F742-E817 HydrophobicContact CZ-CB 3.95Å
743S93.8Very high97.4Very high34 Ų3424.4 Ų24.424%0.23813%0.131CC..G310 helixtrans50.739.2-178.1-46.80000113.2G745 H746 M747 E817S743-G745 PolarHBondContact O-N 3.36Å; S743-G745 VanDerWaalsContact O-N 3.14Å; S743-H746 VanDerWaalsContact O-CB 3.3Å; S743-H746 WeakPolarHBondContact O-CB 3.17Å; S743-H746 PolarHBondContact O-CD2 2.73Å; S743-H746 PolarHBondContact O-N 3.21Å; S743-M747 PolarHBondContact OG-SD 3.36Å; S743-E817 PolarHBondContact OG-OE1 2.85Å
744E94.9Very high97.3Very high140 Ų14025.1 Ų25.165%0.65413%0.13SC*.G310 helixtrans57.427.5177.9-55.7176.7-178.900114.2M740 F742 H746 R792M740-E744 VanDerWaalsContact O-CA 3.28Å; M740-E744 WeakPolarHBondContact O-CA 3.18Å; F742-E744 PolarHBondContact O-N 3.06Å; F742-E744 VanDerWaalsContact O-N 3.15Å; E744-H746 PolarHBondContact O-N 3.2Å; E744-R792 PolarHBondContact O-NH2 3.37Å
745G94.9Very high97.2Very high0 Ų027.3 Ų27.30%015%0.145CC..G310 helixtrans73.512.3-176.200000114V739 F742 S743 M747V739-G745 WeakPolarHBondContact O-CA 3.47Å; V739-G745 PolarHBondContact O-N 3.28Å; F742-G745 PolarHBondContact O-N 2.91Å; F742-G745 VanDerWaalsContact O-N 3.14Å; S743-G745 PolarHBondContact O-N 3.36Å; S743-G745 VanDerWaalsContact O-N 3.14Å; G745-M747 VanDerWaalsContact C-N 3.27Å; G745-M747 PolarHBondContact O-N 2.79Å
746H93.8Very high97Very high48 Ų4832.6 Ų32.622%0.22217%0.17CC..THydrogen-bonded Turntrans-84.12.2179-68-59.4000114.1W5 S743 E744 R792 G796 T800W5-H746 AromaticContact CH2-CE1 3.24Å; W5-H746 WeakPolarHBondContact CH2-CE1 3.46Å; W5-H746 AromaticContact CH2-NE2 3.8Å; W5-H746 AromaticContact CZ3-CE1 3.38Å; W5-H746 WeakPolarHBondContact CZ3-CE1 3.11Å; S743-H746 VanDerWaalsContact O-CB 3.3Å; S743-H746 WeakPolarHBondContact O-CB 3.17Å; S743-H746 PolarHBondContact O-CD2 2.73Å; S743-H746 PolarHBondContact O-N 3.21Å; E744-H746 PolarHBondContact O-N 3.2Å; H746-R792 PolarHBondContact CE1-NH2 3.12Å; H746-R792 PolarHBondContact ND1-NH2 2.65Å; H746-G796 CarbonylContact C-O 3.56Å; H746-G796 CarbonylContact O-C 3.57Å; H746-T800 PolarHBondContact O-OG1 2.75Å
747M95.9Very high96.8Very high11 Ų1130.6 Ų30.65%0.05417%0.165CC..THydrogen-bonded Turntrans-133.914-174.1-70.6-169.262.400113.8F742 S743 G745 V769 T800 Y815F742-M747 HydrophobicContact CD1-CB 4.07Å; F742-M747 HydrophobicContact CE1-CB 3.7Å; S743-M747 PolarHBondContact OG-SD 3.36Å; G745-M747 VanDerWaalsContact C-N 3.27Å; G745-M747 PolarHBondContact O-N 2.79Å; M747-V769 WeakPolarHBondContact O-CG1 3.27Å; M747-T800 HydrophobicContact CE-CG2 4.45Å; M747-Y815 HydrophobicContact CB-CE2 4.26Å; M747-Y815 HydrophobicContact CE-CD2 3.75Å; M747-Y815 HydrophobicContact CE-CE2 3.62Å; M747-Y815 PolarHBondContact O-OH 3.35Å
748G97.5Very high96.6Very high0 Ų032.8 Ų32.80%018%0.179CC..  trans83.6-150.8-175.700000112.4T793G748-T793 WeakPolarHBondContact CA-O 3.46Å
749A98.5Very high96.4Very high1 Ų134 Ų341%0.00819%0.187CC..  trans-110.9121.6-179.500000110.7N738 V739 V774 L777 T793N738-A749 HydrophobicContact CB-CB 4.42Å; N738-A749 WeakPolarHBondContact O-CA 3.37Å; V739-A749 HydrophobicContact CG2-CB 3.64Å; A749-V774 HydrophobicContact CB-CG2 4.07Å; A749-L777 HydrophobicContact CB-CD2 3.76Å; A749-T793 HydrophobicContact CB-CG2 4.3Å
750V98.3Very high96.2Very high0 Ų034.2 Ų34.20%019%0.188CC..  trans-70.1141.4169.267.40000110N738 F742 G752 M753 S766 V769N738-V750 HydrophobicContact CB-CG1 4.4Å; N738-V750 WeakPolarHBondContact CB-O 3.44Å; N738-V750 PolarHBondContact ND2-O 2.73Å; N738-V750 PolarHBondContact O-N 2.79Å; F742-V750 HydrophobicContact CB-CG1 4.09Å; F742-V750 HydrophobicContact CD1-CB 4.13Å; F742-V750 HydrophobicContact CD2-CB 3.83Å; F742-V750 HydrophobicContact CD2-CG1 3.87Å; F742-V750 HydrophobicContact CD2-CG2 4.4Å; F742-V750 HydrophobicContact CE1-CB 4.28Å; F742-V750 HydrophobicContact CE2-CB 3.99Å; F742-V750 HydrophobicContact CE2-CG1 4.47Å; F742-V750 HydrophobicContact CE2-CG2 4.18Å; F742-V750 HydrophobicContact CG-CB 3.89Å; F742-V750 HydrophobicContact CG-CG1 3.92Å; F742-V750 HydrophobicContact CZ-CB 4.21Å; F742-V750 HydrophobicContact CZ-CG2 4.49Å; V750-G752 PolarHBondContact O-N 3.43Å; V750-M753 HydrophobicContact CG1-CE 3.5Å; V750-M753 VanDerWaalsContact CG1-CE 3.5Å; V750-S766 WeakPolarHBondContact CG2-O 3.24Å; V750-V769 HydrophobicContact CB-CG2 4.48Å
751N98.4Very high95.9Very high0 Ų035.4 Ų35.40%019%0.193CC..SBendtrans-62-46.6-171.3-76.2-22.1000113.1Y625 W628 M699 S700 Q765 E768 W770Y625-N751 HydrophobicContact CE1-CB 4.43Å; W628-N751 HydrophobicContact CZ3-CB 4.21Å; M699-N751 CarbonylContact C-O 2.89Å; M699-N751 VanDerWaalsContact CA-O 3.29Å; M699-N751 WeakPolarHBondContact CA-O 3.47Å; S700-N751 PolarHBondContact N-O 2.88Å; S700-N751 WeakPolarHBondContact OG-CA 3.24Å; S700-N751 PolarHBondContact OG-OD1 3.25Å; N751-Q765 WeakPolarHBondContact CB-O 3.3Å; N751-Q765 PolarHBondContact ND2-O 2.96Å; N751-E768 WeakPolarHBondContact CB-O 3.18Å; N751-E768 PolarHBondContact N-O 3.35Å; N751-E768 PolarHBondContact ND2-O 2.99Å; N751-W770 VanDerWaalsContact ND2-CG 3.29Å; N751-W770 PolarHBondContact ND2-NE1 3.09Å
752G98Very high95.4Very high0 Ų034.3 Ų34.30%019%0.185CC..EExtended strand (participates in β ladder)trans-120.2129.2179.200000111.7V750 D760 S766V750-G752 PolarHBondContact O-N 3.43Å; G752-D760 PolarHBondContact O-N 3.06Å; G752-S766 WeakPolarHBondContact CA-O 3.49Å; G752-S766 PolarHBondContact N-O 3.09Å
753M98.1Very high95.1Very high1 Ų134.7 Ų34.71%0.00519%0.188CC..EExtended strand (participates in β ladder)trans-129.3137.7175.4-173.859.578.700109.6I698 L737 N738 F742 V750 V758 P759I698-M753 HydrophobicContact CB-CB 4.47Å; I698-M753 VanDerWaalsContact CD1-O 3.22Å; I698-M753 WeakPolarHBondContact CD1-O 3.21Å; I698-M753 PolarHBondContact N-O 2.81Å; I698-M753 PolarHBondContact O-N 3.36Å; L737-M753 HydrophobicContact CB-CB 4.48Å; L737-M753 HydrophobicContact CB-CG 3.73Å; L737-M753 WeakPolarHBondContact O-CE 3.29Å; N738-M753 HydrophobicContact CB-CB 4.42Å; F742-M753 HydrophobicContact CB-CE 4.07Å; V750-M753 HydrophobicContact CG1-CE 3.5Å; V750-M753 VanDerWaalsContact CG1-CE 3.5Å; M753-V758 PolarHBondContact SD-N 2.71Å; M753-P759 HydrophobicContact CE-CG 4.25Å; M753-P759 VanDerWaalsContact SD-N 3.43Å
754R97.5Very high94.8Very high32 Ų3235 Ų3512%0.12119%0.188CC..  trans-78.2151.6174-58.2-62.1-60.3153.5-1110A693 L694 N696 S697 E756 G757 V758A693-R754 PolarHBondContact O-NH2 3.44Å; L694-R754 VanDerWaalsContact CA-NH1 3.33Å; L694-R754 VanDerWaalsContact CD2-CZ 3.43Å; N696-R754 VanDerWaalsContact OD1-CZ 3.25Å; N696-R754 PolarHBondContact OD1-NH1 3.47Å; N696-R754 PolarHBondContact OD1-NH2 3.46Å; S697-R754 PolarHBondContact OG-NH1 2.85Å; R754-E756 WeakPolarHBondContact CB-OE2 3.16Å; R754-E756 PolarHBondContact O-N 3.48Å; R754-G757 PolarHBondContact O-N 3.33Å; R754-V758 HydrophobicContact CB-CG2 3.77Å; R754-V758 WeakPolarHBondContact CB-O 3.34Å; R754-V758 HydrophobicContact CG-CG2 3.92Å; R754-V758 VanDerWaalsContact CG-O 3.26Å; R754-V758 WeakPolarHBondContact CG-O 3.43Å; R754-V758 PolarHBondContact N-O 3.36Å
755P96.3Very high94.7Very high46 Ų4628.7 Ų28.730%0.29916%0.159SC..THydrogen-bonded Turntrans-61.3-17.9178.721.3-29.4000113.9I698 G757I698-P755 HydrophobicContact CD1-CB 4.24Å; P755-G757 PolarHBondContact O-N 3.17Å
756E95.4Very high94.7Very high135 Ų13528.7 Ų28.763%0.63116%0.159SC*.THydrogen-bonded Turntrans-77.3-4.5173-58.476-158.500113.7R754R754-E756 WeakPolarHBondContact CB-OE2 3.16Å; R754-E756 PolarHBondContact O-N 3.48Å
757G94.6Very high94.6Very high23 Ų2327.2 Ų27.224%0.23715%0.153CC..SBendtrans83.523.818000000114.5R754 P755R754-G757 PolarHBondContact O-N 3.33Å; P755-G757 PolarHBondContact O-N 3.17Å
758V94.6Very high94.7Very high80 Ų8026.8 Ų26.849%0.48515%0.15SC..  trans-114.1138.8174.4-64.50000110.6M753 R754M753-V758 PolarHBondContact SD-N 2.71Å; R754-V758 HydrophobicContact CB-CG2 3.77Å; R754-V758 WeakPolarHBondContact CB-O 3.34Å; R754-V758 HydrophobicContact CG-CG2 3.92Å; R754-V758 VanDerWaalsContact CG-O 3.26Å; R754-V758 WeakPolarHBondContact CG-O 3.43Å; R754-V758 PolarHBondContact N-O 3.36Å
759P94.6Very high94.7Very high26 Ų2626.8 Ų26.817%0.16915%0.15CC..BIsolated β-bridgetrans-55.4144.4-179.5-26.834.5000112.7F742 M753 H761F742-P759 HydrophobicContact CD2-CG 4.19Å; F742-P759 HydrophobicContact CE2-CG 4.42Å; M753-P759 HydrophobicContact CE-CG 4.25Å; M753-P759 VanDerWaalsContact SD-N 3.43Å; P759-H761 PolarHBondContact O-CD2 3.26Å; P759-H761 PolarHBondContact O-N 2.92Å
760D94Very high94.7Very high3 Ų326.8 Ų26.82%0.01615%0.15CC..  trans-76.3119.6172.6-173.8-20.2000109.2S697 G752 S762 S766 D767S697-D760 WeakPolarHBondContact CB-OD2 3.47Å; S697-D760 PolarHBondContact OG-OD2 2.87Å; G752-D760 PolarHBondContact O-N 3.06Å; D760-S762 VanDerWaalsContact OD1-CB 3.23Å; D760-S762 WeakPolarHBondContact OD1-CB 3.41Å; D760-S762 PolarHBondContact OD1-N 2.85Å; D760-S762 PolarHBondContact OD1-OG 3.4Å; D760-S766 CarbonylContact O-C 3.49Å; D760-S766 VanDerWaalsContact O-C 3.28Å; D760-S766 WeakPolarHBondContact O-CB 3.07Å; D760-S766 PolarHBondContact O-OG 2.75Å; D760-D767 PolarHBondContact O-N 3.18Å
761H90.6Very high94.7Very high96 Ų9626.8 Ų26.844%0.44415%0.15SC..  trans-106.919.9-179.5-59.8-59.2000113.3P759 S763 D767P759-H761 PolarHBondContact O-CD2 3.26Å; P759-H761 PolarHBondContact O-N 2.92Å; H761-S763 VanDerWaalsContact C-N 3.31Å; H761-D767 VanDerWaalsContact CE1-CG 3.48Å; H761-D767 IonicContact CE1-OD1 3.12Å; H761-D767 PolarHBondContact CE1-OD1 2.59Å; H761-D767 VanDerWaalsContact CE1-OD1 3.28Å; H761-D767 IonicContact CE1-OD2 3.24Å; H761-D767 PolarHBondContact CE1-OD2 2.79Å; H761-D767 IonicContact ND1-OD1 2.76Å; H761-D767 PolarHBondContact ND1-OD1 3.2Å; H761-D767 IonicContact ND1-OD2 2.7Å; H761-D767 PolarHBondContact ND1-OD2 2.91Å; H761-D767 VanDerWaalsContact ND1-OD2 3.12Å
762S88.3Confident94.7Very high40 Ų4026.8 Ų26.828%0.2815%0.15SC..SBendtrans-66.5-33.7176.850.60000113.8N55 W628 D760 S766N55-S762 PolarHBondContact ND2-O 2.66Å; W628-S762 PolarHBondContact NE1-OG 3.24Å; D760-S762 VanDerWaalsContact OD1-CB 3.23Å; D760-S762 WeakPolarHBondContact OD1-CB 3.41Å; D760-S762 PolarHBondContact OD1-N 2.85Å; D760-S762 PolarHBondContact OD1-OG 3.4Å; S762-S766 PolarHBondContact N-OG 3.12Å
763S88.4Confident94.7Very high13 Ų1326.9 Ų26.99%0.09115%0.151CC..SBendtrans-128.5159.1174.1-1780000109.9G627 H761 Q765 S766G627-S763 VanDerWaalsContact C-OG 3.28Å; G627-S763 WeakPolarHBondContact O-CB 3.28Å; G627-S763 PolarHBondContact O-OG 2.99Å; H761-S763 VanDerWaalsContact C-N 3.31Å; S763-Q765 PolarHBondContact O-N 3.38Å; S763-Q765 PolarHBondContact OG-N 3.43Å; S763-Q765 VanDerWaalsContact OG-N 3.12Å; S763-S766 PolarHBondContact N-OG 3.45Å; S763-S766 PolarHBondContact O-N 3.48Å; S763-S766 PolarHBondContact O-OG 2.93Å
764V87.8Confident94.8Very high39 Ų3926.9 Ų26.924%0.23615%0.151CC..THydrogen-bonded Turntrans-57.6-40.9164.4176.50000109.2F46 S766 D767 E768F46-V764 HydrophobicContact CD2-CG1 3.78Å; F46-V764 HydrophobicContact CE1-CG2 4.3Å; F46-V764 HydrophobicContact CE2-CB 4.15Å; F46-V764 HydrophobicContact CE2-CG1 3.38Å; F46-V764 HydrophobicContact CE2-CG2 3.6Å; F46-V764 HydrophobicContact CZ-CB 4.21Å; F46-V764 HydrophobicContact CZ-CG1 3.82Å; F46-V764 HydrophobicContact CZ-CG2 3.36Å; V764-S766 VanDerWaalsContact C-N 3.3Å; V764-S766 PolarHBondContact O-N 3.35Å; V764-D767 PolarHBondContact O-N 3.13Å; V764-E768 HydrophobicContact CG1-CG 4.39Å; V764-E768 VanDerWaalsContact O-CG 3.3Å; V764-E768 WeakPolarHBondContact O-CG 3.41Å; V764-E768 PolarHBondContact O-N 3.39Å
765Q93.4Very high94.8Very high9 Ų925.4 Ų25.44%0.04215%0.145CC..G310 helixtrans-70.9-26.2-176.5-65.8179.6-24.400112.9Y625 D626 G627 W628 N751 S763 D767 E768 W770Y625-Q765 PolarHBondContact O-OE1 3.07Å; D626-Q765 PolarHBondContact OD1-NE2 3.42Å; G627-Q765 VanDerWaalsContact CA-OE1 3.29Å; G627-Q765 VanDerWaalsContact N-CD 3.32Å; W628-Q765 HydrophobicContact CB-CB 4.42Å; W628-Q765 VanDerWaalsContact N-OE1 3.16Å; N751-Q765 WeakPolarHBondContact CB-O 3.3Å; N751-Q765 PolarHBondContact ND2-O 2.96Å; S763-Q765 PolarHBondContact O-N 3.38Å; S763-Q765 PolarHBondContact OG-N 3.43Å; S763-Q765 VanDerWaalsContact OG-N 3.12Å; Q765-D767 VanDerWaalsContact C-N 3.32Å; Q765-E768 PolarHBondContact O-N 2.82Å; Q765-W770 HydrophobicContact CB-CZ2 4.09Å; Q765-W770 HydrophobicContact CG-CZ2 3.8Å
766S94.3Very high95Very high0 Ų023.2 Ų23.20%013%0.131CC..G310 helixtrans-73.3-27175.464.70000112.2V750 G752 D760 S762 S763 V764V750-S766 WeakPolarHBondContact CG2-O 3.24Å; G752-S766 WeakPolarHBondContact CA-O 3.49Å; G752-S766 PolarHBondContact N-O 3.09Å; D760-S766 CarbonylContact O-C 3.49Å; D760-S766 VanDerWaalsContact O-C 3.28Å; D760-S766 WeakPolarHBondContact O-CB 3.07Å; D760-S766 PolarHBondContact O-OG 2.75Å; S762-S766 PolarHBondContact N-OG 3.12Å; S763-S766 PolarHBondContact N-OG 3.45Å; S763-S766 PolarHBondContact O-N 3.48Å; S763-S766 PolarHBondContact O-OG 2.93Å; V764-S766 VanDerWaalsContact C-N 3.3Å; V764-S766 PolarHBondContact O-N 3.35Å
767D93Very high95.1Very high17 Ų1717 Ų179%0.09110%0.102CC..G310 helixtrans-93.96.7177.6-166.527.2000113.2D760 H761 V764 Q765D760-D767 PolarHBondContact O-N 3.18Å; H761-D767 VanDerWaalsContact CE1-CG 3.48Å; H761-D767 IonicContact CE1-OD1 3.12Å; H761-D767 PolarHBondContact CE1-OD1 2.59Å; H761-D767 VanDerWaalsContact CE1-OD1 3.28Å; H761-D767 IonicContact CE1-OD2 3.24Å; H761-D767 PolarHBondContact CE1-OD2 2.79Å; H761-D767 IonicContact ND1-OD1 2.76Å; H761-D767 PolarHBondContact ND1-OD1 3.2Å; H761-D767 IonicContact ND1-OD2 2.7Å; H761-D767 PolarHBondContact ND1-OD2 2.91Å; H761-D767 VanDerWaalsContact ND1-OD2 3.12Å; V764-D767 PolarHBondContact O-N 3.13Å; Q765-D767 VanDerWaalsContact C-N 3.32Å
768E96.6Very high95.3Very high1 Ų115.9 Ų15.91%0.0059%0.091CC..EExtended strand (participates in β ladder)trans-96.3151.3178.6-83.7174.4162.900111.6N751 V764 Q765 W770 A814 C816 R822N751-E768 WeakPolarHBondContact CB-O 3.18Å; N751-E768 PolarHBondContact N-O 3.35Å; N751-E768 PolarHBondContact ND2-O 2.99Å; V764-E768 HydrophobicContact CG1-CG 4.39Å; V764-E768 VanDerWaalsContact O-CG 3.3Å; V764-E768 WeakPolarHBondContact O-CG 3.41Å; V764-E768 PolarHBondContact O-N 3.39Å; Q765-E768 PolarHBondContact O-N 2.82Å; E768-W770 PolarHBondContact OE2-NE1 3.39Å; E768-A814 HydrophobicContact CB-CB 4.01Å; E768-A814 HydrophobicContact CG-CB 3.89Å; E768-C816 VanDerWaalsContact CG-SG 3.56Å; E768-R822 IonicContact OE1-CZ 3.28Å; E768-R822 IonicContact OE1-NE 3.41Å; E768-R822 PolarHBondContact OE1-NE 3.09Å; E768-R822 IonicContact OE1-NH2 3.44Å; E768-R822 IonicContact OE2-CZ 3.84Å; E768-R822 IonicContact OE2-NE 2.76Å; E768-R822 PolarHBondContact OE2-NE 3.23Å; E768-R822 IonicContact OE2-NH2 2.99Å; E768-R822 PolarHBondContact OE2-NH2 2.87Å
769V98.3Very high95.5Very high0 Ų012 Ų120%07%0.068CC..EExtended strand (participates in β ladder)trans-97.6114159.8177.80000107.3F742 M747 V750 V774 A814 Y815F742-V769 HydrophobicContact CD1-CG2 4.2Å; F742-V769 HydrophobicContact CE1-CG2 3.42Å; F742-V769 VanDerWaalsContact CE1-CG2 3.42Å; F742-V769 HydrophobicContact CZ-CG2 3.99Å; M747-V769 WeakPolarHBondContact O-CG1 3.27Å; V750-V769 HydrophobicContact CB-CG2 4.48Å; V769-V774 HydrophobicContact CG1-CG2 3.58Å; V769-A814 VanDerWaalsContact O-CA 3.22Å; V769-A814 WeakPolarHBondContact O-CA 3.39Å; V769-Y815 HydrophobicContact CB-CD2 4.23Å; V769-Y815 HydrophobicContact CB-CE1 4.4Å; V769-Y815 HydrophobicContact CB-CE2 3.8Å; V769-Y815 HydrophobicContact CG1-CE1 4.24Å; V769-Y815 HydrophobicContact CG1-CE2 4.14Å; V769-Y815 HydrophobicContact CG2-CD2 4.48Å; V769-Y815 HydrophobicContact CG2-CE2 3.94Å; V769-Y815 PolarHBondContact N-O 3.5Å; V769-Y815 PolarHBondContact O-N 2.63Å
770W98.6Very high95.7Very high2 Ų211 Ų111%0.0086%0.06CC..EExtended strand (participates in β ladder)trans-90.7115.4173.4-73.512.9000110T624 Y625 N751 Q765 E768 G772 V773 V774 E813 A814 R822T624-W770 HydrophobicContact CG2-CZ3 4.23Å; Y625-W770 HydrophobicContact CD1-CD2 4.35Å; Y625-W770 AromaticContact CD1-CE3 4Å; Y625-W770 HydrophobicContact CD1-CE3 4Å; Y625-W770 AromaticContact CD1-CH2 3.43Å; Y625-W770 HydrophobicContact CD1-CH2 3.43Å; Y625-W770 VanDerWaalsContact CD1-CH2 3.43Å; Y625-W770 AromaticContact CD1-CZ2 3.79Å; Y625-W770 HydrophobicContact CD1-CZ2 3.79Å; Y625-W770 AromaticContact CD1-CZ3 3.52Å; Y625-W770 HydrophobicContact CD1-CZ3 3.52Å; Y625-W770 HydrophobicContact CD2-CH2 4.49Å; Y625-W770 HydrophobicContact CD2-CZ3 4.2Å; Y625-W770 AromaticContact CE1-CD2 3.94Å; Y625-W770 HydrophobicContact CE1-CD2 3.94Å; Y625-W770 AromaticContact CE1-CE3 3.51Å; Y625-W770 HydrophobicContact CE1-CE3 3.51Å; Y625-W770 AromaticContact CE1-CH2 3.87Å; Y625-W770 HydrophobicContact CE1-CH2 3.87Å; Y625-W770 HydrophobicContact CE1-CZ2 4.22Å; Y625-W770 AromaticContact CE1-CZ3 3.48Å; Y625-W770 HydrophobicContact CE1-CZ3 3.48Å; Y625-W770 VanDerWaalsContact CE1-CZ3 3.48Å; Y625-W770 HydrophobicContact CE2-CZ3 4.15Å; Y625-W770 AromaticContact CG-CH2 3.78Å; Y625-W770 HydrophobicContact CG-CH2 3.78Å; Y625-W770 HydrophobicContact CG-CZ2 4.49Å; Y625-W770 AromaticContact CG-CZ3 3.89Å; Y625-W770 HydrophobicContact CG-CZ3 3.89Å; Y625-W770 AromaticContact CZ-CE3 3.86Å; Y625-W770 AromaticContact CZ-CZ3 3.8Å; N751-W770 VanDerWaalsContact ND2-CG 3.29Å; N751-W770 PolarHBondContact ND2-NE1 3.09Å; Q765-W770 HydrophobicContact CB-CZ2 4.09Å; Q765-W770 HydrophobicContact CG-CZ2 3.8Å; E768-W770 PolarHBondContact OE2-NE1 3.39Å; W770-G772 VanDerWaalsContact C-N 3.31Å; W770-G772 PolarHBondContact O-N 2.86Å; W770-V773 HydrophobicContact CB-CB 3.86Å; W770-V773 HydrophobicContact CB-CG2 3.66Å; W770-V773 HydrophobicContact CD2-CG2 4.38Å; W770-V773 HydrophobicContact CE3-CG2 3.73Å; W770-V773 HydrophobicContact CG-CG2 4.42Å; W770-V773 PolarHBondContact O-N 3.43Å; W770-V774 WeakPolarHBondContact O-CG2 3.23Å; W770-V774 PolarHBondContact O-N 3.01Å; W770-E813 WeakPolarHBondContact CA-O 3.15Å; W770-A814 VanDerWaalsContact CD1-CB 3.45Å; W770-A814 HydrophobicContact CG-CB 4.48Å; W770-R822 VanDerWaalsContact NE1-NH2 3.15Å
771I98.4Very high95.9Very high0 Ų010.8 Ų10.80%06%0.06CC..Hα-helixtrans-60.8-43.3-169.5-64178.4000111V773 V774 Y775 V801 T811 P812 E813 Y815 P829I771-V773 VanDerWaalsContact C-N 3.34Å; I771-V773 PolarHBondContact O-N 3.21Å; I771-V774 WeakPolarHBondContact O-CB 3.37Å; I771-V774 PolarHBondContact O-N 3.04Å; I771-Y775 HydrophobicContact CG2-CD2 4.09Å; I771-Y775 HydrophobicContact CG2-CE2 3.59Å; I771-Y775 WeakPolarHBondContact O-CD2 3.49Å; I771-Y775 PolarHBondContact O-N 3.27Å; I771-V801 HydrophobicContact CD1-CG1 4.34Å; I771-V801 HydrophobicContact CD1-CG2 3.46Å; I771-V801 VanDerWaalsContact CD1-CG2 3.46Å; I771-V801 HydrophobicContact CG1-CG2 4.31Å; I771-T811 HydrophobicContact CB-CG2 4.48Å; I771-T811 HydrophobicContact CD1-CG2 3.53Å; I771-T811 HydrophobicContact CG2-CG2 3.9Å; I771-P812 HydrophobicContact CD1-CG 3.73Å; I771-P812 WeakPolarHBondContact CD1-O 3.15Å; I771-E813 PolarHBondContact N-O 3.25Å; I771-Y815 HydrophobicContact CD1-CD1 4.1Å; I771-Y815 HydrophobicContact CD1-CE1 3.94Å; I771-Y815 HydrophobicContact CG1-CD1 4.2Å; I771-Y815 HydrophobicContact CG1-CE1 3.81Å; I771-P829 HydrophobicContact CB-CG 4.1Å; I771-P829 HydrophobicContact CG2-CB 3.87Å; I771-P829 HydrophobicContact CG2-CG 3.84Å
772G98.3Very high96.2Very high0 Ų06.5 Ų6.50%04%0.04CC..Hα-helixtrans-69.1-30.8178.500000114.2W770 G776 R828 S831W770-G772 VanDerWaalsContact C-N 3.31Å; W770-G772 PolarHBondContact O-N 2.86Å; G772-G776 PolarHBondContact O-N 2.93Å; G772-R828 WeakPolarHBondContact CA-O 3.4Å; G772-S831 WeakPolarHBondContact CA-OG 3.32Å; G772-S831 PolarHBondContact O-OG 3.4Å
773V98.8Very high96.6Very high1 Ų14.9 Ų4.91%0.0063%0.028CC..Hα-helixtrans-69.7-39.4173.6176.30000110.2Y491 Y625 D701 W770 I771 Y775 G776 L777Y491-V773 HydrophobicContact CE1-CG2 4.06Å; Y625-V773 WeakPolarHBondContact OH-CG2 3.27Å; D701-V773 HydrophobicContact CB-CG1 3.86Å; W770-V773 HydrophobicContact CB-CB 3.86Å; W770-V773 HydrophobicContact CB-CG2 3.66Å; W770-V773 HydrophobicContact CD2-CG2 4.38Å; W770-V773 HydrophobicContact CE3-CG2 3.73Å; W770-V773 HydrophobicContact CG-CG2 4.42Å; W770-V773 PolarHBondContact O-N 3.43Å; I771-V773 VanDerWaalsContact C-N 3.34Å; I771-V773 PolarHBondContact O-N 3.21Å; V773-Y775 VanDerWaalsContact C-N 3.34Å; V773-Y775 PolarHBondContact O-N 2.76Å; V773-G776 PolarHBondContact O-N 3.22Å; V773-L777 VanDerWaalsContact O-CB 3.29Å; V773-L777 WeakPolarHBondContact O-CB 3.34Å; V773-L777 PolarHBondContact O-N 3.47Å
774V98.9Very high96.8Very high1 Ų14.5 Ų4.51%0.0062%0.024CC..Hα-helixtrans-58.2-45.2175.2171.50000111.5A749 V769 W770 I771 L777 A778 T793 C797A749-V774 HydrophobicContact CB-CG2 4.07Å; V769-V774 HydrophobicContact CG1-CG2 3.58Å; W770-V774 WeakPolarHBondContact O-CG2 3.23Å; W770-V774 PolarHBondContact O-N 3.01Å; I771-V774 WeakPolarHBondContact O-CB 3.37Å; I771-V774 PolarHBondContact O-N 3.04Å; V774-L777 PolarHBondContact O-N 2.88Å; V774-A778 WeakPolarHBondContact O-CB 3.35Å; V774-A778 PolarHBondContact O-N 3.06Å; V774-T793 HydrophobicContact CG1-CG2 3.84Å; V774-C797 HydrophobicContact CG1-CB 3.84Å
775Y98.9Very high97.2Very high1 Ų15.4 Ų5.40%0.0044%0.042CC..Hα-helixtrans-69.3-37.9177.5-66.1-42.8000112.7I771 V773 A778 A779 A794 P829 S831 V832 M835I771-Y775 HydrophobicContact CG2-CD2 4.09Å; I771-Y775 HydrophobicContact CG2-CE2 3.59Å; I771-Y775 WeakPolarHBondContact O-CD2 3.49Å; I771-Y775 PolarHBondContact O-N 3.27Å; V773-Y775 VanDerWaalsContact C-N 3.34Å; V773-Y775 PolarHBondContact O-N 2.76Å; Y775-A778 PolarHBondContact O-N 2.67Å; Y775-A779 WeakPolarHBondContact O-CB 3.45Å; Y775-A779 PolarHBondContact O-N 3.26Å; Y775-A794 HydrophobicContact CD1-CB 3.89Å; Y775-A794 HydrophobicContact CE1-CB 3.99Å; Y775-P829 WeakPolarHBondContact CD2-O 3.47Å; Y775-P829 HydrophobicContact CE2-CB 4.4Å; Y775-S831 WeakPolarHBondContact CB-OG 3.15Å; Y775-V832 HydrophobicContact CD1-CB 4.31Å; Y775-V832 HydrophobicContact CD1-CG2 4.34Å; Y775-V832 HydrophobicContact CD2-CB 3.83Å; Y775-V832 HydrophobicContact CE1-CB 4.48Å; Y775-V832 HydrophobicContact CE1-CG2 4.31Å; Y775-V832 HydrophobicContact CE2-CB 3.99Å; Y775-V832 HydrophobicContact CG-CB 4Å; Y775-M835 HydrophobicContact CD1-SD 3.72Å; Y775-M835 HydrophobicContact CG-SD 4.41Å; Y775-M835 WeakPolarHBondContact O-CG 3.48Å
776G98.7Very high97.4Very high0 Ų05.4 Ų5.40%04%0.042CC..Hα-helixtrans-62.1-4417200000113G772 V773 A778 A779 T780G772-G776 PolarHBondContact O-N 2.93Å; V773-G776 PolarHBondContact O-N 3.22Å; G776-A778 PolarHBondContact O-N 3.45Å; G776-A779 WeakPolarHBondContact O-CB 3.27Å; G776-A779 PolarHBondContact O-N 2.85Å; G776-T780 PolarHBondContact O-N 2.75Å; G776-T780 PolarHBondContact O-OG1 2.88Å
777L98.9Very high97.5Very high4 Ų49 Ų92%0.0216%0.06CC..Hα-helixtrans-60.5-45.8173.9174.161.3000111.3L731 V734 A749 V773 V774 A779 T780 M781 T793L731-L777 HydrophobicContact CD2-CD1 3.83Å; V734-L777 HydrophobicContact CG1-CD1 4.06Å; V734-L777 HydrophobicContact CG1-CD2 3.52Å; V734-L777 HydrophobicContact CG1-CG 4.42Å; A749-L777 HydrophobicContact CB-CD2 3.76Å; V773-L777 VanDerWaalsContact O-CB 3.29Å; V773-L777 WeakPolarHBondContact O-CB 3.34Å; V773-L777 PolarHBondContact O-N 3.47Å; V774-L777 PolarHBondContact O-N 2.88Å; L777-A779 VanDerWaalsContact C-N 3.33Å; L777-A779 PolarHBondContact O-N 2.77Å; L777-T780 VanDerWaalsContact O-CB 3.31Å; L777-T780 WeakPolarHBondContact O-CB 3.32Å; L777-T780 PolarHBondContact O-N 2.84Å; L777-T780 VanDerWaalsContact O-N 3.13Å; L777-M781 HydrophobicContact CD1-CE 3.9Å; L777-M781 HydrophobicContact CD2-CE 4.21Å; L777-M781 HydrophobicContact CG-CE 3.97Å; L777-M781 WeakPolarHBondContact O-CG 3.21Å; L777-M781 PolarHBondContact O-N 3.45Å; L777-T793 HydrophobicContact CD2-CG2 4.17Å
778A98.9Very high97.7Very high0 Ų014.8 Ų14.80%09%0.087CC..Hα-helixtrans-59.9-42.9176.100000111.8V774 Y775 G776 T780 M781 I782 G790 A794 M835V774-A778 WeakPolarHBondContact O-CB 3.35Å; V774-A778 PolarHBondContact O-N 3.06Å; Y775-A778 PolarHBondContact O-N 2.67Å; G776-A778 PolarHBondContact O-N 3.45Å; A778-T780 VanDerWaalsContact C-N 3.3Å; A778-T780 PolarHBondContact O-N 3Å; A778-M781 PolarHBondContact O-N 3.39Å; A778-I782 WeakPolarHBondContact O-CD1 3.45Å; A778-I782 VanDerWaalsContact O-CG1 3.26Å; A778-I782 WeakPolarHBondContact O-CG1 3.26Å; A778-I782 PolarHBondContact O-N 3.28Å; A778-G790 VanDerWaalsContact CB-O 3.27Å; A778-G790 WeakPolarHBondContact CB-O 3.37Å; A778-A794 HydrophobicContact CB-CB 4.02Å; A778-M835 HydrophobicContact CB-CE 4Å; A778-M835 HydrophobicContact CB-CG 4.09Å; A778-M835 HydrophobicContact CB-SD 3.85Å
779A98.6Very high97.8Very high0 Ų016.9 Ų16.90%010%0.097CC..Hα-helixtrans-60.4-40.6174.200000111.9Y775 G776 L777 I782 H783 A834 M835 A838Y775-A779 WeakPolarHBondContact O-CB 3.45Å; Y775-A779 PolarHBondContact O-N 3.26Å; G776-A779 WeakPolarHBondContact O-CB 3.27Å; G776-A779 PolarHBondContact O-N 2.85Å; L777-A779 VanDerWaalsContact C-N 3.33Å; L777-A779 PolarHBondContact O-N 2.77Å; A779-I782 PolarHBondContact O-N 3.44Å; A779-H783 PolarHBondContact O-CD2 3.39Å; A779-H783 VanDerWaalsContact O-CD2 3.24Å; A779-H783 PolarHBondContact O-N 3.07Å; A779-A834 VanDerWaalsContact CB-C 3.5Å; A779-A834 HydrophobicContact CB-CB 3.85Å; A779-A834 WeakPolarHBondContact CB-O 3.18Å; A779-M835 HydrophobicContact CB-CG 4.15Å; A779-A838 HydrophobicContact CB-CB 4.28Å; A779-A838 WeakPolarHBondContact O-CB 3.24Å
780T97.9Very high97.8Very high3 Ų316.9 Ų16.92%0.01810%0.097CC..Hα-helixtrans-62-46.1176.4-47.50000111.8C703 W707 L731 G776 L777 A778 I782 H783 E784C703-T780 HydrophobicContact CB-CG2 4.41Å; W707-T780 HydrophobicContact CB-CG2 3.92Å; W707-T780 WeakPolarHBondContact CB-OG1 3.3Å; L731-T780 HydrophobicContact CD1-CG2 4.09Å; L731-T780 HydrophobicContact CD2-CG2 3.9Å; G776-T780 PolarHBondContact O-N 2.75Å; G776-T780 PolarHBondContact O-OG1 2.88Å; L777-T780 VanDerWaalsContact O-CB 3.31Å; L777-T780 WeakPolarHBondContact O-CB 3.32Å; L777-T780 PolarHBondContact O-N 2.84Å; L777-T780 VanDerWaalsContact O-N 3.13Å; A778-T780 VanDerWaalsContact C-N 3.3Å; A778-T780 PolarHBondContact O-N 3Å; T780-I782 VanDerWaalsContact C-N 3.33Å; T780-I782 PolarHBondContact O-N 3.41Å; T780-H783 PolarHBondContact O-N 3.17Å; T780-E784 PolarHBondContact O-N 3.42Å
781M98.5Very high97.8Very high0 Ų017.2 Ų17.20%010%0.099CC..Hα-helixtrans-59.1-44.3175.1-72.7-179.1179.400111.1L731 F735 L777 A778 E784 G785 M786 E789L731-M781 HydrophobicContact CD2-CG 4.39Å; F735-M781 HydrophobicContact CB-CE 3.75Å; F735-M781 HydrophobicContact CD2-CE 4.29Å; F735-M781 HydrophobicContact CD2-SD 4.46Å; F735-M781 HydrophobicContact CG-CE 4.48Å; L777-M781 HydrophobicContact CD1-CE 3.9Å; L777-M781 HydrophobicContact CD2-CE 4.21Å; L777-M781 HydrophobicContact CG-CE 3.97Å; L777-M781 WeakPolarHBondContact O-CG 3.21Å; L777-M781 PolarHBondContact O-N 3.45Å; A778-M781 PolarHBondContact O-N 3.39Å; M781-E784 CarbonylContact O-C 3.3Å; M781-E784 PolarHBondContact O-N 2.83Å; M781-E784 VanDerWaalsContact O-N 3.14Å; M781-G785 PolarHBondContact O-N 2.58Å; M781-M786 HydrophobicContact CB-CB 3.95Å; M781-M786 WeakPolarHBondContact O-CA 3.35Å; M781-M786 WeakPolarHBondContact O-CB 3.11Å; M781-M786 PolarHBondContact O-N 3.2Å; M781-E789 HydrophobicContact SD-CB 3.75Å
782I98Very high97.8Very high5 Ų519.8 Ų19.83%0.02611%0.108CC..Hα-helixtrans-61.9-46.1178-66.5163.5000111.2A778 A779 T780 E784 G785 L787 M835 A838 L839A778-I782 WeakPolarHBondContact O-CD1 3.45Å; A778-I782 VanDerWaalsContact O-CG1 3.26Å; A778-I782 WeakPolarHBondContact O-CG1 3.26Å; A778-I782 PolarHBondContact O-N 3.28Å; A779-I782 PolarHBondContact O-N 3.44Å; T780-I782 VanDerWaalsContact C-N 3.33Å; T780-I782 PolarHBondContact O-N 3.41Å; I782-E784 PolarHBondContact O-N 3.12Å; I782-E784 VanDerWaalsContact O-N 3.12Å; I782-G785 PolarHBondContact O-N 3.19Å; I782-L787 HydrophobicContact CD1-CD1 4.47Å; I782-L787 HydrophobicContact CG1-CD1 4.07Å; I782-M835 HydrophobicContact CD1-CB 4.24Å; I782-M835 HydrophobicContact CD1-CE 4.07Å; I782-M835 HydrophobicContact CD1-CG 4.49Å; I782-A838 HydrophobicContact CB-CB 3.91Å; I782-A838 HydrophobicContact CG2-CB 3.68Å; I782-L839 HydrophobicContact CD1-CD2 4.34Å; I782-L839 HydrophobicContact CD1-CG 4.31Å; I782-L839 HydrophobicContact CG2-CD2 3.98Å; I782-L839 HydrophobicContact CG2-CG 4.22Å
783H95Very high97.8Very high7 Ų719.8 Ų19.83%0.03211%0.108CC..Hα-helixtrans-58.7-24.4176.1-81.8-60.4000114.2R710 A779 T780 A838R710-H783 HydrophobicContact CB-CB 3.94Å; R710-H783 HydrophobicContact CG-CB 4.24Å; R710-H783 PolarHBondContact NH1-O 3.02Å; A779-H783 PolarHBondContact O-CD2 3.39Å; A779-H783 VanDerWaalsContact O-CD2 3.24Å; A779-H783 PolarHBondContact O-N 3.07Å; T780-H783 PolarHBondContact O-N 3.17Å; H783-A838 VanDerWaalsContact CE1-CA 3.46Å; H783-A838 WeakPolarHBondContact CE1-CA 3.4Å; H783-A838 WeakPolarHBondContact NE2-CB 3.32Å
784E94.3Very high97.8Very high4 Ų419.7 Ų19.72%0.01911%0.108CC..THydrogen-bonded Turntrans-99.912.5176.7-65.1-52.7143.400114H706 R710 I727 R728 L731 T780 M781 I782 M786H706-E784 IonicContact CD2-OE1 3.01Å; H706-E784 IonicContact CE1-OE1 2.8Å; H706-E784 PolarHBondContact CE1-OE1 3.38Å; H706-E784 IonicContact NE2-OE1 2.78Å; H706-E784 PolarHBondContact NE2-OE1 3.07Å; R710-E784 IonicContact CZ-OE1 2.84Å; R710-E784 IonicContact NH1-OE1 3.19Å; R710-E784 PolarHBondContact NH1-OE1 2.87Å; R710-E784 IonicContact NH1-OE2 3.19Å; I727-E784 HydrophobicContact CG2-CG 4.1Å; R728-E784 HydrophobicContact CG-CB 4.29Å; R728-E784 PolarHBondContact NE-O 3.18Å; L731-E784 HydrophobicContact CD1-CB 4.1Å; L731-E784 HydrophobicContact CD1-CG 3.94Å; T780-E784 PolarHBondContact O-N 3.42Å; M781-E784 CarbonylContact O-C 3.3Å; M781-E784 PolarHBondContact O-N 2.83Å; M781-E784 VanDerWaalsContact O-N 3.14Å; I782-E784 PolarHBondContact O-N 3.12Å; I782-E784 VanDerWaalsContact O-N 3.12Å; E784-M786 VanDerWaalsContact C-N 3.34Å
785G94.8Very high97.7Very high58 Ų5821 Ų2160%0.59811%0.114SC*.THydrogen-bonded Turntrans75.120.5175.900000114.2M781 I782M781-G785 PolarHBondContact O-N 2.58Å; I782-G785 PolarHBondContact O-N 3.19Å
786M97.3Very high97.6Very high9 Ų921.1 Ų21.14%0.04412%0.115CC..  trans-10057175.7-60.9175.763.900109.8L731 K732 M781 E784 E788 E789 G790L731-M786 HydrophobicContact CB-CE 4.3Å; L731-M786 HydrophobicContact CB-SD 3.91Å; L731-M786 HydrophobicContact CD1-SD 4.35Å; K732-M786 HydrophobicContact CB-CE 4.25Å; K732-M786 HydrophobicContact CD-CE 4.17Å; M781-M786 HydrophobicContact CB-CB 3.95Å; M781-M786 WeakPolarHBondContact O-CA 3.35Å; M781-M786 WeakPolarHBondContact O-CB 3.11Å; M781-M786 PolarHBondContact O-N 3.2Å; E784-M786 VanDerWaalsContact C-N 3.34Å; M786-E788 PolarHBondContact O-N 3.05Å; M786-E789 VanDerWaalsContact C-OE2 3.31Å; M786-E789 WeakPolarHBondContact CA-OE2 3.21Å; M786-E789 HydrophobicContact CB-CB 4.24Å; M786-E789 WeakPolarHBondContact CB-OE2 3.44Å; M786-E789 HydrophobicContact CE-CB 4.21Å; M786-E789 HydrophobicContact CE-CG 3.97Å; M786-E789 PolarHBondContact O-N 3.2Å; M786-G790 PolarHBondContact O-N 2.63Å
787L97.3Very high97.5Very high75 Ų7521.1 Ų21.139%0.39312%0.115SC..Hα-helixtrans-61.4-43-172.4175.361.8000112.2I782 M791 L839I782-L787 HydrophobicContact CD1-CD1 4.47Å; I782-L787 HydrophobicContact CG1-CD1 4.07Å; L787-M791 HydrophobicContact CD1-CE 3.9Å; L787-M791 HydrophobicContact CD1-CG 3.87Å; L787-M791 HydrophobicContact CG-CG 4.44Å; L787-M791 WeakPolarHBondContact O-CB 3.06Å; L787-M791 VanDerWaalsContact O-CG 3.27Å; L787-M791 WeakPolarHBondContact O-CG 3.22Å; L787-M791 PolarHBondContact O-N 3.47Å; L787-L839 HydrophobicContact CD1-CD2 3.76Å
788E97.2Very high97.4Very high139 Ų13921.1 Ų21.165%0.6512%0.115SC*.Hα-helixtrans-67.3-43.6-178-64-166.4152.200111.2M786 M791 R792M786-E788 PolarHBondContact O-N 3.05Å; E788-M791 PolarHBondContact O-N 2.84Å; E788-R792 VanDerWaalsContact O-CB 3.24Å; E788-R792 WeakPolarHBondContact O-CB 3.39Å; E788-R792 PolarHBondContact O-N 3.34Å
789E98.6Very high97.2Very high45 Ų4522.7 Ų22.721%0.2112%0.121CC..Hα-helixtrans-63-45.1176.5-62.693.9147.700111.6F735 M781 M786 R792 T793F735-E789 HydrophobicContact CD1-CB 4.21Å; F735-E789 HydrophobicContact CD1-CG 3.64Å; F735-E789 HydrophobicContact CD2-CB 3.6Å; F735-E789 HydrophobicContact CD2-CG 3.99Å; F735-E789 HydrophobicContact CE1-CB 4.33Å; F735-E789 HydrophobicContact CE1-CG 3.7Å; F735-E789 HydrophobicContact CE2-CB 3.75Å; F735-E789 HydrophobicContact CE2-CG 4.06Å; F735-E789 WeakPolarHBondContact CE2-O 3.45Å; F735-E789 HydrophobicContact CG-CB 3.84Å; F735-E789 HydrophobicContact CG-CG 3.78Å; F735-E789 HydrophobicContact CZ-CB 4.11Å; F735-E789 HydrophobicContact CZ-CG 3.91Å; M781-E789 HydrophobicContact SD-CB 3.75Å; M786-E789 VanDerWaalsContact C-OE2 3.31Å; M786-E789 WeakPolarHBondContact CA-OE2 3.21Å; M786-E789 HydrophobicContact CB-CB 4.24Å; M786-E789 WeakPolarHBondContact CB-OE2 3.44Å; M786-E789 HydrophobicContact CE-CB 4.21Å; M786-E789 HydrophobicContact CE-CG 3.97Å; M786-E789 PolarHBondContact O-N 3.2Å; E789-R792 PolarHBondContact O-N 2.89Å; E789-T793 VanDerWaalsContact O-CB 3.31Å; E789-T793 WeakPolarHBondContact O-CB 3.26Å; E789-T793 PolarHBondContact O-N 2.9Å; E789-T793 PolarHBondContact O-OG1 3.42Å
790G98.4Very high97Very high0 Ų022.7 Ų22.70%012%0.121CC..Hα-helixtrans-61.7-47.8177.200000112.2A778 M786 T793 A794A778-G790 VanDerWaalsContact CB-O 3.27Å; A778-G790 WeakPolarHBondContact CB-O 3.37Å; M786-G790 PolarHBondContact O-N 2.63Å; G790-T793 PolarHBondContact O-N 3.37Å; G790-A794 PolarHBondContact O-N 2.98Å; G790-A794 VanDerWaalsContact O-N 3.13Å
791M98.1Very high96.9Very high9 Ų922.6 Ų22.64%0.04412%0.121CC..Hα-helixtrans-64.2-42.5177.9-73.7-68.1-179.400112.1M1 L417 P418 W420 L787 E788 T793 A794 E795 M835 L839M1-M791 HydrophobicContact CE-CG 4.21Å; L417-M791 HydrophobicContact CD2-CE 4.18Å; P418-M791 HydrophobicContact CG-SD 4.47Å; W420-M791 HydrophobicContact CH2-SD 4.27Å; W420-M791 HydrophobicContact CZ2-CB 4.47Å; W420-M791 WeakPolarHBondContact CZ2-O 3.34Å; W420-M791 HydrophobicContact CZ2-SD 3.9Å; L787-M791 HydrophobicContact CD1-CE 3.9Å; L787-M791 HydrophobicContact CD1-CG 3.87Å; L787-M791 HydrophobicContact CG-CG 4.44Å; L787-M791 WeakPolarHBondContact O-CB 3.06Å; L787-M791 VanDerWaalsContact O-CG 3.27Å; L787-M791 WeakPolarHBondContact O-CG 3.22Å; L787-M791 PolarHBondContact O-N 3.47Å; E788-M791 PolarHBondContact O-N 2.84Å; M791-T793 VanDerWaalsContact C-N 3.34Å; M791-T793 PolarHBondContact O-N 2.92Å; M791-A794 PolarHBondContact O-N 2.83Å; M791-E795 VanDerWaalsContact O-CB 3.28Å; M791-E795 WeakPolarHBondContact O-CB 3.39Å; M791-E795 PolarHBondContact O-N 2.69Å; M791-M835 HydrophobicContact SD-CE 4.14Å; M791-L839 HydrophobicContact CE-CD1 3.84Å; M791-L839 HydrophobicContact CE-CD2 3.95Å; M791-L839 HydrophobicContact CE-CG 4.46Å
792R97.9Very high96.8Very high54 Ų5422.6 Ų22.620%0.20412%0.121CC..Hα-helixtrans-62.7-41.8177.917858.4179.6-174.70.3111.9F735 M740 E744 H746 E788 E789 E795 G796F735-R792 HydrophobicContact CE2-CB 4.12Å; F735-R792 HydrophobicContact CE2-CG 4.12Å; F735-R792 HydrophobicContact CZ-CB 4.37Å; F735-R792 HydrophobicContact CZ-CG 4.2Å; M740-R792 HydrophobicContact SD-CG 4.35Å; E744-R792 PolarHBondContact O-NH2 3.37Å; H746-R792 PolarHBondContact CE1-NH2 3.12Å; H746-R792 PolarHBondContact ND1-NH2 2.65Å; E788-R792 VanDerWaalsContact O-CB 3.24Å; E788-R792 WeakPolarHBondContact O-CB 3.39Å; E788-R792 PolarHBondContact O-N 3.34Å; E789-R792 PolarHBondContact O-N 2.89Å; R792-E795 PolarHBondContact O-N 3.39Å; R792-G796 PolarHBondContact O-N 3.39Å
793T98.5Very high96.5Very high0 Ų023.3 Ų23.30%012%0.124CC..Hα-helixtrans-60.5-48.7178.3-60.40000111.2V739 G748 A749 V774 L777 E789 G790 M791V739-T793 HydrophobicContact CG2-CG2 3.77Å; G748-T793 WeakPolarHBondContact CA-O 3.46Å; A749-T793 HydrophobicContact CB-CG2 4.3Å; V774-T793 HydrophobicContact CG1-CG2 3.84Å; L777-T793 HydrophobicContact CD2-CG2 4.17Å; E789-T793 VanDerWaalsContact O-CB 3.31Å; E789-T793 WeakPolarHBondContact O-CB 3.26Å; E789-T793 PolarHBondContact O-N 2.9Å; E789-T793 PolarHBondContact O-OG1 3.42Å; G790-T793 PolarHBondContact O-N 3.37Å; M791-T793 VanDerWaalsContact C-N 3.34Å; M791-T793 PolarHBondContact O-N 2.92Å
794A98.6Very high96.4Very high0 Ų027.7 Ų27.70%014%0.14CC..Hα-helixtrans-70.9-37.2178.700000113.4W420 Y775 A778 G790 M791 G796 C797 Y798 M835W420-A794 HydrophobicContact CH2-CB 3.6Å; W420-A794 HydrophobicContact CZ3-CB 4.09Å; Y775-A794 HydrophobicContact CD1-CB 3.89Å; Y775-A794 HydrophobicContact CE1-CB 3.99Å; A778-A794 HydrophobicContact CB-CB 4.02Å; G790-A794 PolarHBondContact O-N 2.98Å; G790-A794 VanDerWaalsContact O-N 3.13Å; M791-A794 PolarHBondContact O-N 2.83Å; A794-G796 PolarHBondContact O-N 2.89Å; A794-C797 WeakPolarHBondContact O-CB 3.35Å; A794-C797 PolarHBondContact O-N 2.9Å; A794-Y798 PolarHBondContact O-N 3.01Å; A794-M835 HydrophobicContact CB-CE 3.66Å; A794-M835 HydrophobicContact CB-SD 3.74Å
795E97.9Very high96.3Very high29 Ų2927.5 Ų27.514%0.13614%0.139CC..Hα-helixtrans-60.1-46179.9-176.6174.9-16400111.9W420 M791 R792 C797 Y798 R799W420-E795 HydrophobicContact CD2-CB 4.05Å; W420-E795 HydrophobicContact CD2-CG 4.02Å; W420-E795 HydrophobicContact CG-CG 4.09Å; W420-E795 HydrophobicContact CH2-CB 4.25Å; W420-E795 HydrophobicContact CZ2-CB 3.67Å; W420-E795 HydrophobicContact CZ2-CG 4.42Å; M791-E795 VanDerWaalsContact O-CB 3.28Å; M791-E795 WeakPolarHBondContact O-CB 3.39Å; M791-E795 PolarHBondContact O-N 2.69Å; R792-E795 PolarHBondContact O-N 3.39Å; E795-C797 PolarHBondContact O-N 2.75Å; E795-Y798 PolarHBondContact O-N 2.79Å; E795-R799 HydrophobicContact CG-CG 4.17Å; E795-R799 WeakPolarHBondContact O-CG 3.47Å; E795-R799 PolarHBondContact O-N 3.26Å; E795-R799 IonicContact OE1-CZ 2.67Å; E795-R799 VanDerWaalsContact OE1-CZ 3.22Å; E795-R799 IonicContact OE1-NE 2.73Å; E795-R799 PolarHBondContact OE1-NE 2.87Å; E795-R799 IonicContact OE1-NH2 3.42Å; E795-R799 PolarHBondContact OE1-NH2 3.08Å
796G96.3Very high96.3Very high3 Ų324.9 Ų24.93%0.03111%0.112CC..Hα-helixtrans-57.9-38.7178.800000112.6H746 R792 A794 T800H746-G796 CarbonylContact C-O 3.56Å; H746-G796 CarbonylContact O-C 3.57Å; R792-G796 PolarHBondContact O-N 3.39Å; A794-G796 PolarHBondContact O-N 2.89Å; G796-T800 WeakPolarHBondContact O-CB 3.45Å; G796-T800 PolarHBondContact O-N 3.19Å; G796-T800 PolarHBondContact O-OG1 2.88Å
797C96.3Very high96.2Very high0 Ų024.5 Ų24.50%011%0.11CC..Hα-helixtrans-66.7-53.5175.6-177.30000112V774 A794 E795 R799 T800 V801V774-C797 HydrophobicContact CG1-CB 3.84Å; A794-C797 WeakPolarHBondContact O-CB 3.35Å; A794-C797 PolarHBondContact O-N 2.9Å; E795-C797 PolarHBondContact O-N 2.75Å; C797-R799 PolarHBondContact O-N 3.04Å; C797-T800 WeakPolarHBondContact O-CB 3.37Å; C797-T800 PolarHBondContact O-N 2.78Å; C797-V801 VanDerWaalsContact O-CG2 3.31Å; C797-V801 WeakPolarHBondContact O-CG2 3.3Å; C797-V801 PolarHBondContact O-N 3.15Å
798Y97.3Very high96.2Very high4 Ų421 Ų212%0.0169%0.093CC..Hα-helixtrans-55.6-50.6179.9168.1-95.6000111.9W420 S423 A424 A794 E795 T800 V801 W802 E803W420-Y798 HydrophobicContact CB-CD1 3.7Å; W420-Y798 HydrophobicContact CB-CE1 3.67Å; W420-Y798 HydrophobicContact CE3-CD1 4.1Å; W420-Y798 AromaticContact CE3-CG 3.99Å; W420-Y798 HydrophobicContact CE3-CG 3.99Å; W420-Y798 HydrophobicContact CG-CD1 4.43Å; S423-Y798 WeakPolarHBondContact CB-OH 3.27Å; S423-Y798 PolarHBondContact OG-OH 3.19Å; A424-Y798 HydrophobicContact CB-CD2 3.52Å; A424-Y798 HydrophobicContact CB-CE2 3.98Å; A424-Y798 HydrophobicContact CB-CG 4.24Å; A794-Y798 PolarHBondContact O-N 3.01Å; E795-Y798 PolarHBondContact O-N 2.79Å; Y798-T800 VanDerWaalsContact C-N 3.3Å; Y798-T800 PolarHBondContact O-N 3.46Å; Y798-V801 PolarHBondContact O-N 2.99Å; Y798-W802 HydrophobicContact CD2-CB 4.05Å; Y798-W802 AromaticContact CD2-CD1 3.47Å; Y798-W802 VanDerWaalsContact CD2-CD1 3.47Å; Y798-W802 HydrophobicContact CD2-CD2 4.39Å; Y798-W802 AromaticContact CD2-CG 3.7Å; Y798-W802 HydrophobicContact CD2-CG 3.7Å; Y798-W802 HydrophobicContact CE2-CB 3.72Å; Y798-W802 AromaticContact CE2-CD1 3.74Å; Y798-W802 AromaticContact CE2-CD2 3.89Å; Y798-W802 HydrophobicContact CE2-CD2 3.89Å; Y798-W802 HydrophobicContact CE2-CE3 4.5Å; Y798-W802 AromaticContact CE2-CG 3.48Å; Y798-W802 HydrophobicContact CE2-CG 3.48Å; Y798-W802 VanDerWaalsContact CE2-CG 3.48Å; Y798-W802 WeakPolarHBondContact O-CB 3.33Å; Y798-W802 PolarHBondContact O-N 3.5Å; Y798-E803 HydrophobicContact CE1-CG 4.14Å
799R95.1Very high96.2Very high32 Ų3214.4 Ų14.412%0.1216%0.062CC..Iπ-helixtrans-62.6-39.9-177.8-65.3-169.9177.9-73.82.9112W5 E795 C797 E803 R804W5-R799 PolarHBondContact O-NH2 3.48Å; E795-R799 HydrophobicContact CG-CG 4.17Å; E795-R799 WeakPolarHBondContact O-CG 3.47Å; E795-R799 PolarHBondContact O-N 3.26Å; E795-R799 IonicContact OE1-CZ 2.67Å; E795-R799 VanDerWaalsContact OE1-CZ 3.22Å; E795-R799 IonicContact OE1-NE 2.73Å; E795-R799 PolarHBondContact OE1-NE 2.87Å; E795-R799 IonicContact OE1-NH2 3.42Å; E795-R799 PolarHBondContact OE1-NH2 3.08Å; C797-R799 PolarHBondContact O-N 3.04Å; R799-E803 WeakPolarHBondContact CG-OE2 3.44Å; R799-E803 IonicContact CZ-OE2 3.55Å; R799-E803 IonicContact NH1-OE1 2.78Å; R799-E803 PolarHBondContact NH1-OE1 2.76Å; R799-E803 IonicContact NH1-OE2 2.77Å; R799-E803 PolarHBondContact NH1-OE2 2.92Å; R799-E803 WeakPolarHBondContact O-CA 3.27Å; R799-E803 WeakPolarHBondContact O-CB 3.34Å; R799-E803 PolarHBondContact O-N 2.81Å; R799-E803 VanDerWaalsContact O-N 3.13Å; R799-R804 PolarHBondContact O-N 2.84Å
800T94.6Very high96.2Very high1 Ų112.4 Ų12.41%0.0065%0.052CC..Iπ-helixtrans-58-57.5174-68.70000110H746 M747 G796 C797 Y798 R804 L805 Y815H746-T800 PolarHBondContact O-OG1 2.75Å; M747-T800 HydrophobicContact CE-CG2 4.45Å; G796-T800 WeakPolarHBondContact O-CB 3.45Å; G796-T800 PolarHBondContact O-N 3.19Å; G796-T800 PolarHBondContact O-OG1 2.88Å; C797-T800 WeakPolarHBondContact O-CB 3.37Å; C797-T800 PolarHBondContact O-N 2.78Å; Y798-T800 VanDerWaalsContact C-N 3.3Å; Y798-T800 PolarHBondContact O-N 3.46Å; T800-R804 PolarHBondContact O-N 3.47Å; T800-R804 PolarHBondContact OG1-NH2 3.17Å; T800-L805 HydrophobicContact CG2-CD1 3.59Å; T800-L805 HydrophobicContact CG2-CG 3.94Å; T800-L805 VanDerWaalsContact O-CB 3.32Å; T800-L805 WeakPolarHBondContact O-CB 3.36Å; T800-L805 WeakPolarHBondContact O-CG 3.33Å; T800-L805 PolarHBondContact O-N 2.99Å; T800-Y815 HydrophobicContact CG2-CD2 4.42Å; T800-Y815 HydrophobicContact CG2-CE1 4.39Å; T800-Y815 HydrophobicContact CG2-CE2 3.89Å
801V95.6Very high96.1Very high1 Ų112.4 Ų12.41%0.0065%0.052CC..Iπ-helixtrans-68.5-51.4-171.4173.80000112.4I771 C797 Y798 G806 M807 T811 Y815I771-V801 HydrophobicContact CD1-CG1 4.34Å; I771-V801 HydrophobicContact CD1-CG2 3.46Å; I771-V801 VanDerWaalsContact CD1-CG2 3.46Å; I771-V801 HydrophobicContact CG1-CG2 4.31Å; C797-V801 VanDerWaalsContact O-CG2 3.31Å; C797-V801 WeakPolarHBondContact O-CG2 3.3Å; C797-V801 PolarHBondContact O-N 3.15Å; Y798-V801 PolarHBondContact O-N 2.99Å; V801-G806 PolarHBondContact O-N 3.22Å; V801-M807 HydrophobicContact CG1-CB 3.75Å; V801-M807 WeakPolarHBondContact O-CB 3.17Å; V801-M807 PolarHBondContact O-N 3.46Å; V801-T811 HydrophobicContact CG1-CG2 4.03Å; V801-Y815 HydrophobicContact CG2-CD1 4.18Å; V801-Y815 HydrophobicContact CG2-CE1 3.58Å
802W95.1Very high96.1Very high0 Ų012 Ų120%05%0.05CC..Iπ-helixtrans-86.1-38.7-169.8-7575.7000113.2W31 N427 E428 Y798 A808 F809W31-W802 HydrophobicContact CB-CE3 4.26Å; W31-W802 HydrophobicContact CB-CZ3 4.43Å; W31-W802 HydrophobicContact CD2-CE3 4.07Å; W31-W802 HydrophobicContact CD2-CZ3 4.33Å; W31-W802 HydrophobicContact CE3-CZ3 4.38Å; W31-W802 AromaticContact CG-CE3 3.93Å; W31-W802 HydrophobicContact CG-CE3 3.93Å; W31-W802 HydrophobicContact CG-CZ3 4.37Å; W31-W802 PolarHBondContact NE1-O 2.71Å; N427-W802 HydrophobicContact CB-CH2 3.37Å; N427-W802 HydrophobicContact CB-CZ2 4.01Å; N427-W802 HydrophobicContact CB-CZ3 3.76Å; E428-W802 HydrophobicContact CG-CZ2 4.44Å; E428-W802 PolarHBondContact OE1-NE1 3.2Å; Y798-W802 HydrophobicContact CD2-CB 4.05Å; Y798-W802 AromaticContact CD2-CD1 3.47Å; Y798-W802 VanDerWaalsContact CD2-CD1 3.47Å; Y798-W802 HydrophobicContact CD2-CD2 4.39Å; Y798-W802 AromaticContact CD2-CG 3.7Å; Y798-W802 HydrophobicContact CD2-CG 3.7Å; Y798-W802 HydrophobicContact CE2-CB 3.72Å; Y798-W802 AromaticContact CE2-CD1 3.74Å; Y798-W802 AromaticContact CE2-CD2 3.89Å; Y798-W802 HydrophobicContact CE2-CD2 3.89Å; Y798-W802 HydrophobicContact CE2-CE3 4.5Å; Y798-W802 AromaticContact CE2-CG 3.48Å; Y798-W802 HydrophobicContact CE2-CG 3.48Å; Y798-W802 VanDerWaalsContact CE2-CG 3.48Å; Y798-W802 WeakPolarHBondContact O-CB 3.33Å; Y798-W802 PolarHBondContact O-N 3.5Å; W802-A808 HydrophobicContact CD2-CB 4.06Å; W802-A808 HydrophobicContact CE3-CB 3.38Å; W802-A808 HydrophobicContact CH2-CB 4.18Å; W802-A808 HydrophobicContact CZ3-CB 3.46Å; W802-A808 VanDerWaalsContact CZ3-CB 3.46Å; W802-F809 HydrophobicContact CH2-CD1 4.18Å; W802-F809 HydrophobicContact CH2-CD2 4.32Å; W802-F809 HydrophobicContact CH2-CE1 4.01Å; W802-F809 HydrophobicContact CH2-CE2 4.18Å; W802-F809 HydrophobicContact CH2-CG 4.32Å; W802-F809 HydrophobicContact CH2-CZ 4.01Å; W802-F809 HydrophobicContact CZ3-CD2 4.21Å; W802-F809 HydrophobicContact CZ3-CE1 4.41Å; W802-F809 AromaticContact CZ3-CE2 3.83Å; W802-F809 HydrophobicContact CZ3-CE2 3.83Å; W802-F809 AromaticContact CZ3-CZ 3.93Å; W802-F809 HydrophobicContact CZ3-CZ 3.93Å
803E92.8Very high96.1Very high20 Ų209.5 Ų9.59%0.0934%0.041CC..Iπ-helixtrans-100.8-37.5-169.8-51.8-178.9151.600112.3S9 L13 F39 Y798 R799S9-E803 VanDerWaalsContact CB-OE2 3.32Å; S9-E803 WeakPolarHBondContact CB-OE2 3.38Å; S9-E803 PolarHBondContact OG-OE1 2.98Å; S9-E803 PolarHBondContact OG-OE2 3.18Å; L13-E803 HydrophobicContact CD1-CB 4.2Å; L13-E803 HydrophobicContact CD1-CG 4.08Å; F39-E803 WeakPolarHBondContact CE1-O 3.36Å; Y798-E803 HydrophobicContact CE1-CG 4.14Å; R799-E803 WeakPolarHBondContact CG-OE2 3.44Å; R799-E803 IonicContact CZ-OE2 3.55Å; R799-E803 IonicContact NH1-OE1 2.78Å; R799-E803 PolarHBondContact NH1-OE1 2.76Å; R799-E803 IonicContact NH1-OE2 2.77Å; R799-E803 PolarHBondContact NH1-OE2 2.92Å; R799-E803 WeakPolarHBondContact O-CA 3.27Å; R799-E803 WeakPolarHBondContact O-CB 3.34Å; R799-E803 PolarHBondContact O-N 2.81Å; R799-E803 VanDerWaalsContact O-N 3.13Å
804R92.3Very high96Very high99 Ų999.5 Ų9.537%0.3744%0.041SC..Iπ-helixtrans-94.1-46.9-177.8-169.8170.767.5-151.4-7.5113.4E41 R799 T800E41-R804 HydrophobicContact CB-CG 4.5Å; E41-R804 VanDerWaalsContact OE2-CD 3.3Å; E41-R804 WeakPolarHBondContact OE2-CD 3.3Å; E41-R804 WeakPolarHBondContact OE2-CG 3.48Å; E41-R804 IonicContact OE2-NE 2.77Å; E41-R804 PolarHBondContact OE2-NE 3.19Å; R799-R804 PolarHBondContact O-N 2.84Å; T800-R804 PolarHBondContact O-N 3.47Å; T800-R804 PolarHBondContact OG1-NH2 3.17Å
805L92.8Very high95.9Very high0 Ų09.5 Ų9.50%04%0.041CC..SBendtrans-88.7-14.7-173.8-61.7-175.3000114.4E41 R43 Q93 T800 M807E41-L805 HydrophobicContact CB-CD2 4.01Å; E41-L805 HydrophobicContact CG-CD2 3.69Å; E41-L805 WeakPolarHBondContact OE1-CD2 3.11Å; E41-L805 WeakPolarHBondContact OE2-CD2 3.24Å; R43-L805 HydrophobicContact CG-CD2 4.09Å; Q93-L805 PolarHBondContact NE2-O 2.92Å; T800-L805 HydrophobicContact CG2-CD1 3.59Å; T800-L805 HydrophobicContact CG2-CG 3.94Å; T800-L805 VanDerWaalsContact O-CB 3.32Å; T800-L805 WeakPolarHBondContact O-CB 3.36Å; T800-L805 WeakPolarHBondContact O-CG 3.33Å; T800-L805 PolarHBondContact O-N 2.99Å; L805-M807 VanDerWaalsContact C-N 3.33Å; L805-M807 HydrophobicContact CB-CE 4.21Å; L805-M807 HydrophobicContact CB-CG 3.99Å; L805-M807 HydrophobicContact CB-SD 3.97Å; L805-M807 HydrophobicContact CD1-CE 4.01Å; L805-M807 HydrophobicContact CD1-SD 3.83Å; L805-M807 PolarHBondContact O-N 3.29Å
806G94.1Very high95.5Very high3 Ų38.5 Ų8.53%0.0314%0.037CC..  trans64.336-17900000114F39 Q93 V801 Q810F39-G806 VanDerWaalsContact CD1-CA 3.47Å; Q93-G806 WeakPolarHBondContact CG-O 3.25Å; V801-G806 PolarHBondContact O-N 3.22Å; G806-Q810 PolarHBondContact O-NE2 3.14Å
807M95.9Very high95Very high0 Ų013.2 Ų13.20%06%0.058CC..  trans-96.516.9179.2-67.3173.9175.500113R43 L91 V801 L805 F809 Q810 T811 P812 Y821R43-M807 HydrophobicContact CB-CE 4.38Å; L91-M807 HydrophobicContact CD1-CE 4.16Å; L91-M807 HydrophobicContact CD1-CG 3.69Å; L91-M807 HydrophobicContact CD2-CE 3.67Å; L91-M807 HydrophobicContact CD2-CG 4.45Å; V801-M807 HydrophobicContact CG1-CB 3.75Å; V801-M807 WeakPolarHBondContact O-CB 3.17Å; V801-M807 PolarHBondContact O-N 3.46Å; L805-M807 VanDerWaalsContact C-N 3.33Å; L805-M807 HydrophobicContact CB-CE 4.21Å; L805-M807 HydrophobicContact CB-CG 3.99Å; L805-M807 HydrophobicContact CB-SD 3.97Å; L805-M807 HydrophobicContact CD1-CE 4.01Å; L805-M807 HydrophobicContact CD1-SD 3.83Å; L805-M807 PolarHBondContact O-N 3.29Å; M807-F809 PolarHBondContact O-N 3.46Å; M807-Q810 HydrophobicContact CB-CG 4.16Å; M807-Q810 CarbonylContact O-C 3.5Å; M807-Q810 VanDerWaalsContact O-C 3.28Å; M807-Q810 VanDerWaalsContact O-CG 3.25Å; M807-Q810 WeakPolarHBondContact O-CG 3.48Å; M807-Q810 PolarHBondContact O-N 3.1Å; M807-T811 PolarHBondContact O-N 2.88Å; M807-T811 VanDerWaalsContact O-N 3.16Å; M807-P812 HydrophobicContact SD-CG 3.8Å; M807-Y821 HydrophobicContact CE-CD1 3.91Å; M807-Y821 HydrophobicContact CE-CG 3.97Å
808A96.4Very high94Very high3 Ų321 Ų213%0.0259%0.087CC..THydrogen-bonded Turntrans-51.5133.4171.800000111.3W31 W802 Q810W31-A808 HydrophobicContact CD2-CB 4.21Å; W31-A808 HydrophobicContact CE3-CB 4.06Å; W31-A808 HydrophobicContact CH2-CB 3.48Å; W31-A808 VanDerWaalsContact CH2-CB 3.48Å; W31-A808 HydrophobicContact CZ2-CB 3.63Å; W31-A808 HydrophobicContact CZ3-CB 3.71Å; W802-A808 HydrophobicContact CD2-CB 4.06Å; W802-A808 HydrophobicContact CE3-CB 3.38Å; W802-A808 HydrophobicContact CH2-CB 4.18Å; W802-A808 HydrophobicContact CZ3-CB 3.46Å; W802-A808 VanDerWaalsContact CZ3-CB 3.46Å; A808-Q810 PolarHBondContact O-N 2.74Å; A808-Q810 VanDerWaalsContact O-N 3.16Å
809F98.1Very high93.4Very high0 Ų025.2 Ų25.20%011%0.11CC..THydrogen-bonded Turntrans58.522-177.7-51.6-76.3000114.7W31 G96 A97 R117 Y173 A175 N427 Y430 W802 M807W31-F809 AromaticContact CE3-CE2 3.86Å; W31-F809 HydrophobicContact CE3-CE2 3.86Å; W31-F809 HydrophobicContact CZ3-CD2 4.33Å; W31-F809 AromaticContact CZ3-CE2 3.91Å; W31-F809 HydrophobicContact CZ3-CE2 3.91Å; G96-F809 VanDerWaalsContact C-CG 3.41Å; G96-F809 VanDerWaalsContact CA-CD2 3.4Å; G96-F809 WeakPolarHBondContact O-CB 3.37Å; G96-F809 VanDerWaalsContact O-CG 3.26Å; G96-F809 WeakPolarHBondContact O-CG 3.43Å; A97-F809 HydrophobicContact CB-CE1 3.94Å; A97-F809 HydrophobicContact CB-CZ 3.96Å; R117-F809 PolarHBondContact NH1-O 2.87Å; R117-F809 PolarHBondContact NH2-O 2.8Å; Y173-F809 HydrophobicContact CE1-CE2 4.48Å; A175-F809 HydrophobicContact CB-CE2 3.98Å; A175-F809 HydrophobicContact CB-CZ 3.57Å; N427-F809 HydrophobicContact CB-CE1 4.18Å; N427-F809 HydrophobicContact CB-CZ 4.23Å; Y430-F809 HydrophobicContact CD1-CD1 4.08Å; Y430-F809 HydrophobicContact CD2-CB 4.2Å; Y430-F809 HydrophobicContact CD2-CD1 4.16Å; Y430-F809 HydrophobicContact CE2-CB 4.32Å; Y430-F809 WeakPolarHBondContact CE2-O 3.5Å; Y430-F809 HydrophobicContact CG-CB 4.44Å; Y430-F809 AromaticContact CG-CD1 3.68Å; Y430-F809 HydrophobicContact CG-CD1 3.68Å; Y430-F809 PolarHBondContact OH-O 3.03Å; W802-F809 HydrophobicContact CH2-CD1 4.18Å; W802-F809 HydrophobicContact CH2-CD2 4.32Å; W802-F809 HydrophobicContact CH2-CE1 4.01Å; W802-F809 HydrophobicContact CH2-CE2 4.18Å; W802-F809 HydrophobicContact CH2-CG 4.32Å; W802-F809 HydrophobicContact CH2-CZ 4.01Å; W802-F809 HydrophobicContact CZ3-CD2 4.21Å; W802-F809 HydrophobicContact CZ3-CE1 4.41Å; W802-F809 AromaticContact CZ3-CE2 3.83Å; W802-F809 HydrophobicContact CZ3-CE2 3.83Å; W802-F809 AromaticContact CZ3-CZ 3.93Å; W802-F809 HydrophobicContact CZ3-CZ 3.93Å; M807-F809 PolarHBondContact O-N 3.46Å
810Q97.3Very high93.2Very high3 Ų325 Ų251%0.01411%0.111CC..  trans-151.830.9171.463.7-171.3-42.600110.8L91 R92 Y95 Y430 G806 M807 A808 L824 A825L91-Q810 HydrophobicContact CD1-CG 4.46Å; R92-Q810 PolarHBondContact O-NE2 3.21Å; R92-Q810 PolarHBondContact O-OE1 3.44Å; Y95-Q810 HydrophobicContact CD2-CB 4.03Å; Y95-Q810 VanDerWaalsContact CD2-CD 3.44Å; Y95-Q810 HydrophobicContact CD2-CG 4.16Å; Y430-Q810 WeakPolarHBondContact OH-CA 3.43Å; Y430-Q810 PolarHBondContact OH-N 3.23Å; G806-Q810 PolarHBondContact O-NE2 3.14Å; M807-Q810 HydrophobicContact CB-CG 4.16Å; M807-Q810 CarbonylContact O-C 3.5Å; M807-Q810 VanDerWaalsContact O-C 3.28Å; M807-Q810 VanDerWaalsContact O-CG 3.25Å; M807-Q810 WeakPolarHBondContact O-CG 3.48Å; M807-Q810 PolarHBondContact O-N 3.1Å; A808-Q810 PolarHBondContact O-N 2.74Å; A808-Q810 VanDerWaalsContact O-N 3.16Å; Q810-L824 HydrophobicContact CG-CD2 4.45Å; Q810-A825 HydrophobicContact CB-CB 4.36Å; Q810-A825 PolarHBondContact O-N 2.96Å
811T98.1Very high93.1Very high0 Ų025 Ų250%011%0.111CC..  trans-48.6122-177.6-56.40000109.7E428 Y430 I771 V801 M807 A825 Y826 P829E428-T811 VanDerWaalsContact CD-OG1 3.31Å; E428-T811 WeakPolarHBondContact OE1-CG2 3.42Å; E428-T811 PolarHBondContact OE1-OG1 3.18Å; E428-T811 WeakPolarHBondContact OE2-CB 3.49Å; E428-T811 PolarHBondContact OE2-OG1 3.43Å; Y430-T811 PolarHBondContact OH-N 2.76Å; I771-T811 HydrophobicContact CB-CG2 4.48Å; I771-T811 HydrophobicContact CD1-CG2 3.53Å; I771-T811 HydrophobicContact CG2-CG2 3.9Å; V801-T811 HydrophobicContact CG1-CG2 4.03Å; M807-T811 PolarHBondContact O-N 2.88Å; M807-T811 VanDerWaalsContact O-N 3.16Å; T811-A825 CarbonylContact O-C 3.53Å; T811-A825 VanDerWaalsContact O-CA 3.28Å; T811-A825 WeakPolarHBondContact O-CA 3.39Å; T811-A825 PolarHBondContact O-N 3.33Å; T811-A825 VanDerWaalsContact O-N 3.15Å; T811-Y826 PolarHBondContact O-N 2.65Å; T811-P829 HydrophobicContact CG2-CB 3.73Å; T811-P829 HydrophobicContact CG2-CG 3.48Å; T811-P829 VanDerWaalsContact CG2-CG 3.48Å
812P97.4Very high93Very high0 Ų026.4 Ų26.40%012%0.116CC..  trans-78.3174.7-174.131.2-35.7000112.5I771 M807 R822 S823 L824I771-P812 HydrophobicContact CD1-CG 3.73Å; I771-P812 WeakPolarHBondContact CD1-O 3.15Å; M807-P812 HydrophobicContact SD-CG 3.8Å; P812-R822 WeakPolarHBondContact CB-O 3.24Å; P812-S823 CarbonylContact C-O 3.55Å; P812-S823 WeakPolarHBondContact CA-O 3.12Å; P812-S823 WeakPolarHBondContact CB-O 3.14Å; P812-L824 HydrophobicContact CB-CD2 4.39Å
813E97.5Very high92.9Very high1 Ų126.5 Ų26.51%0.00512%0.117CC..SBendtrans-63.4-53.1161.1171.263.1155.600109.6W770 I771 R822 S823 Y826 R828W770-E813 WeakPolarHBondContact CA-O 3.15Å; I771-E813 PolarHBondContact N-O 3.25Å; E813-R822 PolarHBondContact N-O 2.88Å; E813-S823 PolarHBondContact N-O 2.83Å; E813-Y826 HydrophobicContact CB-CD1 3.55Å; E813-Y826 HydrophobicContact CB-CD2 3.97Å; E813-Y826 HydrophobicContact CB-CE1 3.63Å; E813-Y826 HydrophobicContact CB-CE2 4.08Å; E813-Y826 HydrophobicContact CB-CG 3.7Å; E813-Y826 HydrophobicContact CG-CD1 4.13Å; E813-Y826 HydrophobicContact CG-CE1 3.77Å; E813-Y826 WeakPolarHBondContact OE2-CD1 3.09Å; E813-Y826 WeakPolarHBondContact OE2-CE1 3.33Å; E813-R828 VanDerWaalsContact CD-NE 3.31Å; E813-R828 IonicContact OE1-CZ 3.17Å; E813-R828 IonicContact OE1-NE 3.13Å; E813-R828 PolarHBondContact OE1-NE 3.05Å; E813-R828 IonicContact OE1-NH2 3.86Å; E813-R828 PolarHBondContact OE1-NH2 3.02Å; E813-R828 WeakPolarHBondContact OE2-CB 3.49Å; E813-R828 IonicContact OE2-NE 2.68Å; E813-R828 PolarHBondContact OE2-NE 3.17Å
814A96.9Very high93Very high0 Ų025.8 Ų25.80%011%0.114CC..EExtended strand (participates in β ladder)trans-144157-168.100000115E768 V769 W770 Y821 R822E768-A814 HydrophobicContact CB-CB 4.01Å; E768-A814 HydrophobicContact CG-CB 3.89Å; V769-A814 VanDerWaalsContact O-CA 3.22Å; V769-A814 WeakPolarHBondContact O-CA 3.39Å; W770-A814 VanDerWaalsContact CD1-CB 3.45Å; W770-A814 HydrophobicContact CG-CB 4.48Å; A814-Y821 CarbonylContact O-C 3.49Å; A814-Y821 WeakPolarHBondContact O-CA 3.49Å; A814-R822 HydrophobicContact CB-CB 4.4Å; A814-R822 PolarHBondContact N-O 2.84Å; A814-R822 PolarHBondContact O-N 2.84Å
815Y95.3Very high93.2Very high1 Ų121.1 Ų21.10%0.00410%0.096CC..EExtended strand (participates in β ladder)trans-143.9155162.959.5-94.7000110.5M747 V769 I771 T800 V801 I820M747-Y815 HydrophobicContact CB-CE2 4.26Å; M747-Y815 HydrophobicContact CE-CD2 3.75Å; M747-Y815 HydrophobicContact CE-CE2 3.62Å; M747-Y815 PolarHBondContact O-OH 3.35Å; V769-Y815 HydrophobicContact CB-CD2 4.23Å; V769-Y815 HydrophobicContact CB-CE1 4.4Å; V769-Y815 HydrophobicContact CB-CE2 3.8Å; V769-Y815 HydrophobicContact CG1-CE1 4.24Å; V769-Y815 HydrophobicContact CG1-CE2 4.14Å; V769-Y815 HydrophobicContact CG2-CD2 4.48Å; V769-Y815 HydrophobicContact CG2-CE2 3.94Å; V769-Y815 PolarHBondContact N-O 3.5Å; V769-Y815 PolarHBondContact O-N 2.63Å; I771-Y815 HydrophobicContact CD1-CD1 4.1Å; I771-Y815 HydrophobicContact CD1-CE1 3.94Å; I771-Y815 HydrophobicContact CG1-CD1 4.2Å; I771-Y815 HydrophobicContact CG1-CE1 3.81Å; T800-Y815 HydrophobicContact CG2-CD2 4.42Å; T800-Y815 HydrophobicContact CG2-CE1 4.39Å; T800-Y815 HydrophobicContact CG2-CE2 3.89Å; V801-Y815 HydrophobicContact CG2-CD1 4.18Å; V801-Y815 HydrophobicContact CG2-CE1 3.58Å; Y815-I820 WeakPolarHBondContact CA-O 3.2Å; Y815-I820 WeakPolarHBondContact CB-O 3.46Å
816C91.2Very high93.4Very high7 Ų721.3 Ų21.35%0.04710%0.097CC..EExtended strand (participates in β ladder)trans-103.4173.8175-56.50000110.6R43 E768 R818 I820R43-C816 PolarHBondContact NH1-O 2.48Å; E768-C816 VanDerWaalsContact CG-SG 3.56Å; C816-R818 PolarHBondContact O-N 3.22Å; C816-I820 PolarHBondContact N-O 2.9Å
817E85Confident93.6Very high102 Ų10221.2 Ų21.248%0.47710%0.096SC..SBendtrans-60.2-37165.1-170.1174.4-146.200110.9F742 S743 N819F742-E817 HydrophobicContact CE2-CB 4.03Å; F742-E817 HydrophobicContact CZ-CB 3.95Å; S743-E817 PolarHBondContact OG-OE1 2.85Å; E817-N819 PolarHBondContact O-N 2.96Å
818R76.3Confident93.7Very high164 Ų16421.3 Ų21.362%0.61910%0.096SC*.SBendtrans-80.463.2-172.5-60.3-178.5-178.8-1794.7114.9C816 I820C816-R818 PolarHBondContact O-N 3.22Å; R818-I820 WeakPolarHBondContact O-CB 3.44Å; R818-I820 WeakPolarHBondContact O-CD1 3.18Å; R818-I820 WeakPolarHBondContact O-CG1 3.17Å; R818-I820 PolarHBondContact O-N 3.46Å
819N83.8Confident93.9Very high93 Ų9321.1 Ų21.150%0.49710%0.095SC..SBendtrans43.824.2169.1-68.9-39.9000117.1R43 K44 E817R43-N819 VanDerWaalsContact CA-O 3.25Å; R43-N819 WeakPolarHBondContact CA-O 3.43Å; R43-N819 WeakPolarHBondContact CB-O 3.26Å; K44-N819 PolarHBondContact N-O 2.89Å; E817-N819 PolarHBondContact O-N 2.96Å
820I89.9Confident93.9Very high27 Ų2721.2 Ų21.214%0.13810%0.095CC..EExtended strand (participates in β ladder)trans-119.5147.9-175.8-70.2159.5000108.6R43 K44 F46 D50 Y815 C816 R818R43-I820 PolarHBondContact NH1-O 2.96Å; K44-I820 VanDerWaalsContact O-CA 3.32Å; K44-I820 WeakPolarHBondContact O-CA 3.3Å; F46-I820 HydrophobicContact CB-CG2 3.71Å; F46-I820 HydrophobicContact CD2-CG2 3.92Å; F46-I820 HydrophobicContact CG-CG2 4.32Å; D50-I820 HydrophobicContact CB-CD1 4.1Å; Y815-I820 WeakPolarHBondContact CA-O 3.2Å; Y815-I820 WeakPolarHBondContact CB-O 3.46Å; C816-I820 PolarHBondContact N-O 2.9Å; R818-I820 WeakPolarHBondContact O-CB 3.44Å; R818-I820 WeakPolarHBondContact O-CD1 3.18Å; R818-I820 WeakPolarHBondContact O-CG1 3.17Å; R818-I820 PolarHBondContact O-N 3.46Å
821Y92.8Very high94Very high2 Ų221 Ų211%0.0089%0.094CC..EExtended strand (participates in β ladder)trans-132164.3169.470.1-94.1000110.6R43 K44 P45 F46 L89 L91 M807 A814 L824R43-Y821 HydrophobicContact CB-CD1 3.72Å; R43-Y821 HydrophobicContact CB-CE1 4.36Å; K44-Y821 WeakPolarHBondContact O-CD1 3.45Å; K44-Y821 PolarHBondContact O-N 3.11Å; K44-Y821 VanDerWaalsContact O-N 3.09Å; P45-Y821 CarbonylContact C-O 3.39Å; P45-Y821 WeakPolarHBondContact CA-O 3.43Å; P45-Y821 HydrophobicContact CB-CE1 4.43Å; P45-Y821 HydrophobicContact CB-CE2 3.95Å; P45-Y821 WeakPolarHBondContact CD-OH 3.43Å; P45-Y821 VanDerWaalsContact N-CE1 3.34Å; F46-Y821 PolarHBondContact N-O 2.8Å; L89-Y821 PolarHBondContact O-OH 3.21Å; L91-Y821 HydrophobicContact CB-CE1 3.62Å; L91-Y821 HydrophobicContact CD2-CE1 4.35Å; L91-Y821 PolarHBondContact N-OH 3.38Å; M807-Y821 HydrophobicContact CE-CD1 3.91Å; M807-Y821 HydrophobicContact CE-CG 3.97Å; A814-Y821 CarbonylContact O-C 3.49Å; A814-Y821 WeakPolarHBondContact O-CA 3.49Å; Y821-L824 HydrophobicContact CD2-CD1 4.49Å; Y821-L824 HydrophobicContact CD2-CD2 3.83Å; Y821-L824 HydrophobicContact CD2-CG 3.87Å; Y821-L824 HydrophobicContact CE2-CD1 3.65Å; Y821-L824 HydrophobicContact CE2-CD2 3.8Å; Y821-L824 HydrophobicContact CE2-CG 3.46Å; Y821-L824 VanDerWaalsContact CE2-CG 3.46Å
822R93.3Very high94Very high29 Ų2921 Ų2111%0.1099%0.094CC..EExtended strand (participates in β ladder)trans-139.9134.2175.4-175.2171.66276.20.6111.2F46 Y480 E768 W770 P812 E813 A814F46-R822 HydrophobicContact CB-CB 4.46Å; Y480-R822 VanDerWaalsContact OH-CD 3.28Å; Y480-R822 WeakPolarHBondContact OH-CD 3.4Å; Y480-R822 WeakPolarHBondContact OH-CG 3.41Å; Y480-R822 PolarHBondContact OH-NH1 2.83Å; E768-R822 IonicContact OE1-CZ 3.28Å; E768-R822 IonicContact OE1-NE 3.41Å; E768-R822 PolarHBondContact OE1-NE 3.09Å; E768-R822 IonicContact OE1-NH2 3.44Å; E768-R822 IonicContact OE2-CZ 3.84Å; E768-R822 IonicContact OE2-NE 2.76Å; E768-R822 PolarHBondContact OE2-NE 3.23Å; E768-R822 IonicContact OE2-NH2 2.99Å; E768-R822 PolarHBondContact OE2-NH2 2.87Å; W770-R822 VanDerWaalsContact NE1-NH2 3.15Å; P812-R822 WeakPolarHBondContact CB-O 3.24Å; E813-R822 PolarHBondContact N-O 2.88Å; A814-R822 HydrophobicContact CB-CB 4.4Å; A814-R822 PolarHBondContact N-O 2.84Å; A814-R822 PolarHBondContact O-N 2.84Å
823S92.9Very high94.1Very high2 Ų221.4 Ų21.41%0.01410%0.096CC..SBendtrans57.785.6174.8-152.70000114.4E479 Y480 P812 E813 Y826E479-S823 WeakPolarHBondContact OE2-CA 3.44Å; E479-S823 PolarHBondContact OE2-N 2.95Å; Y480-S823 VanDerWaalsContact CD2-OG 3.24Å; Y480-S823 WeakPolarHBondContact CD2-OG 3.21Å; Y480-S823 VanDerWaalsContact CE2-CB 3.48Å; Y480-S823 WeakPolarHBondContact CE2-OG 3.4Å; Y480-S823 VanDerWaalsContact CG-OG 3.29Å; Y480-S823 VanDerWaalsContact CZ-CB 3.5Å; P812-S823 CarbonylContact C-O 3.55Å; P812-S823 WeakPolarHBondContact CA-O 3.12Å; P812-S823 WeakPolarHBondContact CB-O 3.14Å; E813-S823 PolarHBondContact N-O 2.83Å; S823-Y826 WeakPolarHBondContact OG-CD2 3.44Å; S823-Y826 VanDerWaalsContact OG-CE2 3.23Å; S823-Y826 WeakPolarHBondContact OG-CE2 3.32Å
824L95.1Very high94.1Very high6 Ų621.3 Ų21.33%0.03110%0.095CC..SBendtrans-68.1150.6176.5-67.9168.3000112.5L89 L91 Q478 E479 Q810 P812 Y821L89-L824 HydrophobicContact CB-CD1 4.49Å; L91-L824 HydrophobicContact CB-CD1 4.39Å; L91-L824 HydrophobicContact CD1-CD2 3.99Å; Q478-L824 PolarHBondContact N-O 2.66Å; E479-L824 PolarHBondContact OE2-N 3.11Å; Q810-L824 HydrophobicContact CG-CD2 4.45Å; P812-L824 HydrophobicContact CB-CD2 4.39Å; Y821-L824 HydrophobicContact CD2-CD1 4.49Å; Y821-L824 HydrophobicContact CD2-CD2 3.83Å; Y821-L824 HydrophobicContact CD2-CG 3.87Å; Y821-L824 HydrophobicContact CE2-CD1 3.65Å; Y821-L824 HydrophobicContact CE2-CD2 3.8Å; Y821-L824 HydrophobicContact CE2-CG 3.46Å; Y821-L824 VanDerWaalsContact CE2-CG 3.46Å
825A96.4Very high94.2Very high0 Ų021.3 Ų21.30%010%0.095CC..SBendtrans49.183.9-179.800000111Y430 F431 G477 Q478 Q810 T811Y430-A825 WeakPolarHBondContact OH-CA 3.09Å; F431-A825 HydrophobicContact CE2-CB 4.23Å; F431-A825 WeakPolarHBondContact CE2-O 3.48Å; G477-A825 CarbonylContact C-O 3.41Å; G477-A825 WeakPolarHBondContact CA-O 3.48Å; Q478-A825 HydrophobicContact CB-CB 4.03Å; Q478-A825 HydrophobicContact CG-CB 3.61Å; Q478-A825 PolarHBondContact N-O 3Å; Q810-A825 HydrophobicContact CB-CB 4.36Å; Q810-A825 PolarHBondContact O-N 2.96Å; T811-A825 CarbonylContact O-C 3.53Å; T811-A825 VanDerWaalsContact O-CA 3.28Å; T811-A825 WeakPolarHBondContact O-CA 3.39Å; T811-A825 PolarHBondContact O-N 3.33Å; T811-A825 VanDerWaalsContact O-N 3.15Å
826Y98.2Very high94.4Very high5 Ų521.6 Ų21.62%0.0210%0.097CC..BIsolated β-bridgetrans-121.3155.1-167.1-152-107.5000111.9E476 Y480 V488 T811 E813 S823 R828 P829E476-Y826 HydrophobicContact CG-CE1 4.36Å; E476-Y826 HydrophobicContact CG-CE2 3.7Å; E476-Y826 WeakPolarHBondContact CG-OH 3.1Å; E476-Y826 CarbonylContact O-C 3.58Å; E476-Y826 WeakPolarHBondContact O-CA 3.5Å; E476-Y826 WeakPolarHBondContact O-CD2 3.25Å; E476-Y826 PolarHBondContact OE1-OH 3.23Å; Y480-Y826 AromaticContact CD2-CE2 3.43Å; Y480-Y826 HydrophobicContact CD2-CE2 3.43Å; Y480-Y826 VanDerWaalsContact CD2-CE2 3.43Å; Y480-Y826 AromaticContact CD2-CZ 3.98Å; Y480-Y826 AromaticContact CE2-CE2 4Å; Y480-Y826 HydrophobicContact CE2-CE2 4Å; Y480-Y826 HydrophobicContact CG-CE2 4.16Å; V488-Y826 HydrophobicContact CG1-CD1 4.38Å; V488-Y826 HydrophobicContact CG1-CE1 3.67Å; T811-Y826 PolarHBondContact O-N 2.65Å; E813-Y826 HydrophobicContact CB-CD1 3.55Å; E813-Y826 HydrophobicContact CB-CD2 3.97Å; E813-Y826 HydrophobicContact CB-CE1 3.63Å; E813-Y826 HydrophobicContact CB-CE2 4.08Å; E813-Y826 HydrophobicContact CB-CG 3.7Å; E813-Y826 HydrophobicContact CG-CD1 4.13Å; E813-Y826 HydrophobicContact CG-CE1 3.77Å; E813-Y826 WeakPolarHBondContact OE2-CD1 3.09Å; E813-Y826 WeakPolarHBondContact OE2-CE1 3.33Å; S823-Y826 WeakPolarHBondContact OG-CD2 3.44Å; S823-Y826 VanDerWaalsContact OG-CE2 3.23Å; S823-Y826 WeakPolarHBondContact OG-CE2 3.32Å; Y826-R828 HydrophobicContact CD1-CB 3.83Å; Y826-R828 HydrophobicContact CE1-CB 4.05Å; Y826-P829 WeakPolarHBondContact O-CD 3.23Å
827M98.3Very high94.7Very high0 Ų021.7 Ų21.70%010%0.097CC..SBendtrans-79.4-34.6-17481.6-173.4-30.100113.7F431 Y474 E476 V488 A492 L830F431-M827 HydrophobicContact CD1-CB 3.85Å; F431-M827 HydrophobicContact CE1-CB 3.35Å; F431-M827 HydrophobicContact CZ-CB 4.18Å; Y474-M827 HydrophobicContact CD1-CE 4.5Å; Y474-M827 HydrophobicContact CD2-CB 4.38Å; Y474-M827 HydrophobicContact CD2-CE 3.53Å; Y474-M827 HydrophobicContact CE1-CE 4.09Å; Y474-M827 HydrophobicContact CE2-CB 3.96Å; Y474-M827 HydrophobicContact CE2-CE 3.06Å; Y474-M827 HydrophobicContact CG-CE 4.25Å; E476-M827 HydrophobicContact CB-SD 4.38Å; E476-M827 HydrophobicContact CG-SD 4.31Å; E476-M827 PolarHBondContact O-N 2.84Å; V488-M827 HydrophobicContact CB-CG 4.06Å; V488-M827 HydrophobicContact CB-SD 3.67Å; V488-M827 HydrophobicContact CG1-CG 3.3Å; V488-M827 HydrophobicContact CG1-SD 3.64Å; A492-M827 HydrophobicContact CB-CB 4.26Å; A492-M827 HydrophobicContact CB-CG 4.08Å; A492-M827 VanDerWaalsContact CB-O 3.25Å; A492-M827 WeakPolarHBondContact CB-O 3.49Å; M827-L830 VanDerWaalsContact O-CB 3.31Å; M827-L830 WeakPolarHBondContact O-CB 3.23Å; M827-L830 WeakPolarHBondContact O-CG 3.38Å; M827-L830 PolarHBondContact O-N 3.38Å; M827-L830 VanDerWaalsContact O-N 3.08Å
828R98.6Very high95.3Very high2 Ų216.9 Ų16.91%0.0087%0.074CC..G310 helixtrans-54.9-37.6-173.2-145.9-170.6-67.3-91.85.7114.5V488 Y491 T624 G772 E813 Y826 L830 S831V488-R828 HydrophobicContact CG1-CB 3.69Å; V488-R828 HydrophobicContact CG1-CG 3.87Å; Y491-R828 VanDerWaalsContact CB-CG 3.49Å; Y491-R828 HydrophobicContact CD1-CG 4.45Å; Y491-R828 HydrophobicContact CD2-CG 3.87Å; Y491-R828 HydrophobicContact CG-CG 3.7Å; T624-R828 PolarHBondContact OG1-NH1 3.49Å; T624-R828 PolarHBondContact OG1-NH2 2.6Å; G772-R828 WeakPolarHBondContact CA-O 3.4Å; E813-R828 VanDerWaalsContact CD-NE 3.31Å; E813-R828 IonicContact OE1-CZ 3.17Å; E813-R828 IonicContact OE1-NE 3.13Å; E813-R828 PolarHBondContact OE1-NE 3.05Å; E813-R828 IonicContact OE1-NH2 3.86Å; E813-R828 PolarHBondContact OE1-NH2 3.02Å; E813-R828 WeakPolarHBondContact OE2-CB 3.49Å; E813-R828 IonicContact OE2-NE 2.68Å; E813-R828 PolarHBondContact OE2-NE 3.17Å; Y826-R828 HydrophobicContact CD1-CB 3.83Å; Y826-R828 HydrophobicContact CE1-CB 4.05Å; R828-L830 PolarHBondContact O-N 3.38Å; R828-L830 VanDerWaalsContact O-N 3.1Å; R828-S831 WeakPolarHBondContact O-CB 3.42Å; R828-S831 PolarHBondContact O-N 2.85Å; R828-S831 VanDerWaalsContact O-N 3.1Å; R828-S831 PolarHBondContact O-OG 3.03Å
829P98.8Very high96.3Very high0 Ų09.7 Ų9.70%05%0.048CC..G310 helixtrans-55.8-19.2175-28.134.9000116.2I771 Y775 T811 Y826 S831 V832I771-P829 HydrophobicContact CB-CG 4.1Å; I771-P829 HydrophobicContact CG2-CB 3.87Å; I771-P829 HydrophobicContact CG2-CG 3.84Å; Y775-P829 WeakPolarHBondContact CD2-O 3.47Å; Y775-P829 HydrophobicContact CE2-CB 4.4Å; T811-P829 HydrophobicContact CG2-CB 3.73Å; T811-P829 HydrophobicContact CG2-CG 3.48Å; T811-P829 VanDerWaalsContact CG2-CG 3.48Å; Y826-P829 WeakPolarHBondContact O-CD 3.23Å; P829-S831 PolarHBondContact O-N 3.31Å; P829-V832 PolarHBondContact O-N 2.96Å; P829-V832 VanDerWaalsContact O-N 3.09Å
830L98.8Very high96.8Very high1 Ų17.8 Ų7.81%0.0054%0.038CC..G310 helixtrans-58.1-17.1172.4-71.9170.8000113E428 L429 F431 V432 Y474 A492 A495 M827 R828 V832 W833E428-L830 VanDerWaalsContact O-CD2 3.26Å; E428-L830 WeakPolarHBondContact O-CD2 3.39Å; L429-L830 HydrophobicContact CD2-CD2 4.22Å; F431-L830 HydrophobicContact CB-CD1 4.42Å; F431-L830 HydrophobicContact CB-CD2 4.41Å; F431-L830 HydrophobicContact CB-CG 4.44Å; F431-L830 HydrophobicContact CD1-CD1 4.12Å; V432-L830 HydrophobicContact CG2-CD1 4.12Å; V432-L830 HydrophobicContact CG2-CD2 4Å; Y474-L830 HydrophobicContact CE2-CD1 4.16Å; A492-L830 HydrophobicContact CB-CB 4Å; A492-L830 HydrophobicContact CB-CD1 4.16Å; A495-L830 HydrophobicContact CB-CB 4.09Å; A495-L830 HydrophobicContact CB-CD2 4.12Å; M827-L830 VanDerWaalsContact O-CB 3.31Å; M827-L830 WeakPolarHBondContact O-CB 3.23Å; M827-L830 WeakPolarHBondContact O-CG 3.38Å; M827-L830 PolarHBondContact O-N 3.38Å; M827-L830 VanDerWaalsContact O-N 3.08Å; R828-L830 PolarHBondContact O-N 3.38Å; R828-L830 VanDerWaalsContact O-N 3.1Å; L830-V832 PolarHBondContact O-N 3.33Å; L830-W833 WeakPolarHBondContact O-CB 3.38Å; L830-W833 PolarHBondContact O-N 2.96Å; L830-W833 VanDerWaalsContact O-N 3.09Å
831S98.7Very high96.8Very high0 Ų07.4 Ų7.40%04%0.037CC..G310 helixtrans-57.4-10.2169.752.70000115.4Y491 G772 Y775 R828 P829 W833 A834Y491-S831 VanDerWaalsContact O-CA 3.25Å; Y491-S831 WeakPolarHBondContact O-CA 3.2Å; Y491-S831 VanDerWaalsContact O-CB 3.23Å; Y491-S831 WeakPolarHBondContact O-CB 3.46Å; G772-S831 WeakPolarHBondContact CA-OG 3.32Å; G772-S831 PolarHBondContact O-OG 3.4Å; Y775-S831 WeakPolarHBondContact CB-OG 3.15Å; R828-S831 WeakPolarHBondContact O-CB 3.42Å; R828-S831 PolarHBondContact O-N 2.85Å; R828-S831 VanDerWaalsContact O-N 3.1Å; R828-S831 PolarHBondContact O-OG 3.03Å; P829-S831 PolarHBondContact O-N 3.31Å; S831-W833 PolarHBondContact O-N 2.99Å; S831-W833 VanDerWaalsContact O-N 3.09Å; S831-A834 WeakPolarHBondContact O-CA 3.46Å; S831-A834 WeakPolarHBondContact O-CB 3.17Å; S831-A834 PolarHBondContact O-N 3.04Å
832V98.9Very high96.4Very high0 Ų08.9 Ų8.90%05%0.047CC..Hα-helixtrans-52.7-28.2165.966.60000111.9Y421 A424 L425 E428 Y775 P829 L830 A834 M835Y421-V832 HydrophobicContact CE2-CG2 4.05Å; A424-V832 HydrophobicContact CB-CG2 4.37Å; L425-V832 HydrophobicContact CB-CG2 4.38Å; L425-V832 HydrophobicContact CD1-CG1 4.24Å; L425-V832 HydrophobicContact CD1-CG2 4.15Å; E428-V832 HydrophobicContact CB-CG1 3.96Å; E428-V832 HydrophobicContact CG-CG1 4.24Å; Y775-V832 HydrophobicContact CD1-CB 4.31Å; Y775-V832 HydrophobicContact CD1-CG2 4.34Å; Y775-V832 HydrophobicContact CD2-CB 3.83Å; Y775-V832 HydrophobicContact CE1-CB 4.48Å; Y775-V832 HydrophobicContact CE1-CG2 4.31Å; Y775-V832 HydrophobicContact CE2-CB 3.99Å; Y775-V832 HydrophobicContact CG-CB 4Å; P829-V832 PolarHBondContact O-N 2.96Å; P829-V832 VanDerWaalsContact O-N 3.09Å; L830-V832 PolarHBondContact O-N 3.33Å; V832-A834 VanDerWaalsContact C-N 3.3Å; V832-A834 PolarHBondContact O-N 3.36Å; V832-M835 HydrophobicContact CG2-SD 4.4Å; V832-M835 VanDerWaalsContact O-CB 3.31Å; V832-M835 WeakPolarHBondContact O-CB 3.17Å; V832-M835 PolarHBondContact O-N 2.85Å; V832-M835 VanDerWaalsContact O-N 3.14Å
833W98.8Very high95.9Very high7 Ų711.6 Ų11.63%0.0276%0.061CC..Hα-helixtrans-68.6-23.5173.2-80.382.2000114.2W407 I411 L425 L429 F494 A495 M498 L499 L830 S831 M835 Q836 L837W407-W833 HydrophobicContact CH2-CZ2 4.42Å; W407-W833 AromaticContact CZ3-CH2 3.81Å; W407-W833 HydrophobicContact CZ3-CH2 3.81Å; W407-W833 HydrophobicContact CZ3-CZ2 4.03Å; I411-W833 HydrophobicContact CD1-CH2 4.44Å; L425-W833 HydrophobicContact CD1-CD2 3.78Å; L425-W833 HydrophobicContact CD1-CE3 4.35Å; L425-W833 HydrophobicContact CD1-CG 3.96Å; L425-W833 HydrophobicContact CD1-CH2 4.49Å; L425-W833 HydrophobicContact CD1-CZ2 3.98Å; L425-W833 HydrophobicContact CD2-CH2 4.36Å; L425-W833 HydrophobicContact CD2-CZ2 4.27Å; L425-W833 HydrophobicContact CG-CH2 4.34Å; L425-W833 HydrophobicContact CG-CZ2 3.79Å; L425-W833 PolarHBondContact O-NE1 2.85Å; L429-W833 HydrophobicContact CD1-CZ2 3.67Å; L429-W833 HydrophobicContact CD2-CZ2 4.48Å; L429-W833 VanDerWaalsContact CD2-NE1 3.28Å; L429-W833 HydrophobicContact CG-CZ2 4.28Å; F494-W833 HydrophobicContact CB-CB 4.03Å; A495-W833 HydrophobicContact CB-CB 4.18Å; A495-W833 HydrophobicContact CB-CG 3.92Å; M498-W833 HydrophobicContact CB-CE3 4.34Å; M498-W833 HydrophobicContact CE-CE3 3.87Å; M498-W833 HydrophobicContact CE-CZ3 4.21Å; M498-W833 HydrophobicContact SD-CB 4.33Å; M498-W833 HydrophobicContact SD-CE3 3.99Å; M498-W833 VanDerWaalsContact SD-O 3.41Å; L499-W833 HydrophobicContact CD1-CD2 4.11Å; L499-W833 HydrophobicContact CD1-CE3 4.23Å; L499-W833 HydrophobicContact CD1-CH2 3.88Å; L499-W833 HydrophobicContact CD1-CZ2 3.71Å; L499-W833 HydrophobicContact CD1-CZ3 4.12Å; L499-W833 HydrophobicContact CD2-CE3 4.32Å; L499-W833 HydrophobicContact CD2-CH2 3.72Å; L499-W833 HydrophobicContact CD2-CZ2 4.41Å; L499-W833 HydrophobicContact CD2-CZ3 3.65Å; L499-W833 HydrophobicContact CG-CE3 4.24Å; L499-W833 HydrophobicContact CG-CH2 4.21Å; L499-W833 HydrophobicContact CG-CZ3 4.05Å; L830-W833 WeakPolarHBondContact O-CB 3.38Å; L830-W833 PolarHBondContact O-N 2.96Å; L830-W833 VanDerWaalsContact O-N 3.09Å; S831-W833 PolarHBondContact O-N 2.99Å; S831-W833 VanDerWaalsContact O-N 3.09Å; W833-M835 VanDerWaalsContact C-N 3.26Å; W833-M835 PolarHBondContact O-N 3.1Å; W833-Q836 HydrophobicContact CE3-CB 4.35Å; W833-Q836 HydrophobicContact CZ3-CG 4.29Å; W833-Q836 PolarHBondContact O-N 2.76Å; W833-L837 PolarHBondContact O-N 2.93Å
834A98.8Very high95.3Very high0 Ų018 Ų180%09%0.085CC..Hα-helixtrans-65.4-32.4170.200000111.8F494 W707 A779 S831 V832 Q836 L837 A838F494-A834 HydrophobicContact CB-CB 4.3Å; F494-A834 HydrophobicContact CD1-CB 3.7Å; F494-A834 HydrophobicContact CD2-CB 3.85Å; F494-A834 HydrophobicContact CE1-CB 3.89Å; F494-A834 HydrophobicContact CE2-CB 4.04Å; F494-A834 HydrophobicContact CG-CB 3.67Å; F494-A834 HydrophobicContact CZ-CB 4.06Å; W707-A834 HydrophobicContact CZ2-CB 3.6Å; A779-A834 VanDerWaalsContact CB-C 3.5Å; A779-A834 HydrophobicContact CB-CB 3.85Å; A779-A834 WeakPolarHBondContact CB-O 3.18Å; S831-A834 WeakPolarHBondContact O-CA 3.46Å; S831-A834 WeakPolarHBondContact O-CB 3.17Å; S831-A834 PolarHBondContact O-N 3.04Å; V832-A834 VanDerWaalsContact C-N 3.3Å; V832-A834 PolarHBondContact O-N 3.36Å; A834-Q836 VanDerWaalsContact C-N 3.33Å; A834-L837 PolarHBondContact O-N 3.25Å; A834-A838 PolarHBondContact O-N 3.41Å
835M98.8Very high94.3Very high0 Ų021.3 Ų21.30%010%0.103CC..Hα-helixtrans-65-40.6173-60.6174.86000110.8W420 Y421 Y775 A778 A779 I782 M791 A794 V832 W833 A838 L839W420-M835 HydrophobicContact CH2-CE 4.42Å; Y421-M835 HydrophobicContact CD2-CE 4.01Å; Y421-M835 HydrophobicContact CE2-CB 4.05Å; Y421-M835 HydrophobicContact CE2-CE 3.81Å; Y421-M835 HydrophobicContact CE2-SD 4.12Å; Y775-M835 HydrophobicContact CD1-SD 3.72Å; Y775-M835 HydrophobicContact CG-SD 4.41Å; Y775-M835 WeakPolarHBondContact O-CG 3.48Å; A778-M835 HydrophobicContact CB-CE 4Å; A778-M835 HydrophobicContact CB-CG 4.09Å; A778-M835 HydrophobicContact CB-SD 3.85Å; A779-M835 HydrophobicContact CB-CG 4.15Å; I782-M835 HydrophobicContact CD1-CB 4.24Å; I782-M835 HydrophobicContact CD1-CE 4.07Å; I782-M835 HydrophobicContact CD1-CG 4.49Å; M791-M835 HydrophobicContact SD-CE 4.14Å; A794-M835 HydrophobicContact CB-CE 3.66Å; A794-M835 HydrophobicContact CB-SD 3.74Å; V832-M835 HydrophobicContact CG2-SD 4.4Å; V832-M835 VanDerWaalsContact O-CB 3.31Å; V832-M835 WeakPolarHBondContact O-CB 3.17Å; V832-M835 PolarHBondContact O-N 2.85Å; V832-M835 VanDerWaalsContact O-N 3.14Å; W833-M835 VanDerWaalsContact C-N 3.26Å; W833-M835 PolarHBondContact O-N 3.1Å; M835-A838 WeakPolarHBondContact O-CB 3.21Å; M835-A838 PolarHBondContact O-N 2.75Å; M835-L839 VanDerWaalsContact O-CG 3.28Å; M835-L839 WeakPolarHBondContact O-CG 3.4Å; M835-L839 PolarHBondContact O-N 2.74Å
836Q98.6Very high93.1Very high7 Ų726.4 Ų26.43%0.03313%0.13CC..Hα-helixtrans-63-44.9177.6-172.460.853.200110.5I411 Y421 L425 M498 W833 A834 A838 L839 D840I411-Q836 HydrophobicContact CD1-CG 4.37Å; Y421-Q836 VanDerWaalsContact OH-CA 3.31Å; Y421-Q836 WeakPolarHBondContact OH-CA 3.33Å; Y421-Q836 WeakPolarHBondContact OH-CB 3.42Å; Y421-Q836 PolarHBondContact OH-N 3.01Å; Y421-Q836 VanDerWaalsContact OH-N 3.16Å; Y421-Q836 PolarHBondContact OH-OE1 3.48Å; L425-Q836 HydrophobicContact CD1-CB 3.99Å; L425-Q836 HydrophobicContact CD2-CB 4.36Å; L425-Q836 HydrophobicContact CD2-CG 4.29Å; M498-Q836 HydrophobicContact CE-CB 4.3Å; M498-Q836 HydrophobicContact CE-CG 4.24Å; W833-Q836 HydrophobicContact CE3-CB 4.35Å; W833-Q836 HydrophobicContact CZ3-CG 4.29Å; W833-Q836 PolarHBondContact O-N 2.76Å; A834-Q836 VanDerWaalsContact C-N 3.33Å; Q836-A838 VanDerWaalsContact C-N 3.28Å; Q836-A838 PolarHBondContact O-N 3.18Å; Q836-L839 PolarHBondContact O-N 3.33Å; Q836-D840 PolarHBondContact NE2-OD1 3.31Å; Q836-D840 WeakPolarHBondContact O-CB 3.38Å; Q836-D840 VanDerWaalsContact O-CG 3.22Å; Q836-D840 PolarHBondContact O-N 2.89Å
837L98.2Very high91.8Very high9 Ų929.7 Ų29.75%0.04715%0.151CC..Hα-helixtrans-57-41.9173.9-17666.1000112.2F494 M498 L583 A711 W833 A834 T841F494-L837 HydrophobicContact CD1-CD2 3.84Å; F494-L837 HydrophobicContact CE1-CD2 3.71Å; M498-L837 HydrophobicContact CE-CB 4.11Å; M498-L837 HydrophobicContact CE-CD1 4.47Å; M498-L837 HydrophobicContact SD-CB 3.87Å; M498-L837 HydrophobicContact SD-CD1 4.5Å; L583-L837 HydrophobicContact CD2-CD1 4.06Å; A711-L837 HydrophobicContact CB-CD2 4.08Å; W833-L837 PolarHBondContact O-N 2.93Å; A834-L837 PolarHBondContact O-N 3.25Å; L837-T841 WeakPolarHBondContact O-CB 3.5Å; L837-T841 PolarHBondContact O-N 3.02Å; L837-T841 PolarHBondContact O-OG1 3.26Å
838A97.9Very high90.3Very high0 Ų033.9 Ų33.90%018%0.176CC..Hα-helixtrans-66.2-40178.700000112.7A779 I782 H783 A834 M835 Q836 S842A779-A838 HydrophobicContact CB-CB 4.28Å; A779-A838 WeakPolarHBondContact O-CB 3.24Å; I782-A838 HydrophobicContact CB-CB 3.91Å; I782-A838 HydrophobicContact CG2-CB 3.68Å; H783-A838 VanDerWaalsContact CE1-CA 3.46Å; H783-A838 WeakPolarHBondContact CE1-CA 3.4Å; H783-A838 WeakPolarHBondContact NE2-CB 3.32Å; A834-A838 PolarHBondContact O-N 3.41Å; M835-A838 WeakPolarHBondContact O-CB 3.21Å; M835-A838 PolarHBondContact O-N 2.75Å; Q836-A838 VanDerWaalsContact C-N 3.28Å; Q836-A838 PolarHBondContact O-N 3.18Å; A838-S842 WeakPolarHBondContact O-CB 3.28Å; A838-S842 PolarHBondContact O-N 2.96Å; A838-S842 PolarHBondContact O-OG 3.14Å
839L97.2Very high88.6Confident13 Ų1339.2 Ų39.27%0.06820%0.204CC..Hα-helixtrans-64.8-50175.4-69.9164000111.1L417 Y421 I782 L787 M791 M835 Q836 T841 S842 Q843L417-L839 HydrophobicContact CD2-CD1 3.86Å; Y421-L839 HydrophobicContact CE1-CD1 3.85Å; I782-L839 HydrophobicContact CD1-CD2 4.34Å; I782-L839 HydrophobicContact CD1-CG 4.31Å; I782-L839 HydrophobicContact CG2-CD2 3.98Å; I782-L839 HydrophobicContact CG2-CG 4.22Å; L787-L839 HydrophobicContact CD1-CD2 3.76Å; M791-L839 HydrophobicContact CE-CD1 3.84Å; M791-L839 HydrophobicContact CE-CD2 3.95Å; M791-L839 HydrophobicContact CE-CG 4.46Å; M835-L839 VanDerWaalsContact O-CG 3.28Å; M835-L839 WeakPolarHBondContact O-CG 3.4Å; M835-L839 PolarHBondContact O-N 2.74Å; Q836-L839 PolarHBondContact O-N 3.33Å; L839-T841 VanDerWaalsContact C-N 3.25Å; L839-T841 PolarHBondContact O-N 2.91Å; L839-S842 PolarHBondContact O-N 3.26Å; L839-S842 VanDerWaalsContact O-N 3.17Å; L839-Q843 WeakPolarHBondContact O-CG 3.29Å; L839-Q843 PolarHBondContact O-N 2.91Å
840D94.8Very high86.7Confident54 Ų5442.3 Ų42.329%0.28923%0.23SC..Hα-helixtrans-60.6-37.2179.3-66.6-15.9000111.6Q836 R844Q836-D840 PolarHBondContact NE2-OD1 3.31Å; Q836-D840 WeakPolarHBondContact O-CB 3.38Å; Q836-D840 VanDerWaalsContact O-CG 3.22Å; Q836-D840 PolarHBondContact O-N 2.89Å; D840-R844 VanDerWaalsContact O-CG 3.32Å; D840-R844 WeakPolarHBondContact O-CG 3.47Å; D840-R844 PolarHBondContact O-N 3.18Å; D840-R844 PolarHBondContact O-NE 2.91Å
841T89.6Confident84.7Confident19 Ų1949.7 Ų49.712%0.11726%0.262CS..Hα-helixtrans-68.8-45.7176.1-55.70000111.4L837 L839 Q843 R844 D845L837-T841 WeakPolarHBondContact O-CB 3.5Å; L837-T841 PolarHBondContact O-N 3.02Å; L837-T841 PolarHBondContact O-OG1 3.26Å; L839-T841 VanDerWaalsContact C-N 3.25Å; L839-T841 PolarHBondContact O-N 2.91Å; T841-Q843 VanDerWaalsContact C-N 3.32Å; T841-Q843 PolarHBondContact O-N 3.14Å; T841-R844 WeakPolarHBondContact O-CB 3.27Å; T841-R844 PolarHBondContact O-N 3.13Å; T841-R844 PolarHBondContact OG1-NH2 3.09Å; T841-D845 PolarHBondContact O-N 2.73Å
842S85Confident82.7Confident32 Ų3253.9 Ų53.922%0.22429%0.288CS..Hα-helixtrans-62.7-37.7179-57.40000112.5A838 L839 N846A838-S842 WeakPolarHBondContact O-CB 3.28Å; A838-S842 PolarHBondContact O-N 2.96Å; A838-S842 PolarHBondContact O-OG 3.14Å; L839-S842 PolarHBondContact O-N 3.26Å; L839-S842 VanDerWaalsContact O-N 3.17Å; S842-N846 VanDerWaalsContact O-CG 3.32Å; S842-N846 PolarHBondContact O-N 3.27Å; S842-N846 VanDerWaalsContact O-N 3.09Å; S842-N846 PolarHBondContact O-ND2 3.14Å
843Q81.4Confident80.1Confident87 Ų8756.6 Ų56.641%0.40732%0.316SS..Hα-helixtrans-65.4-40.6175.2-71.2-179.33.300112.1L839 T841 T847L839-Q843 WeakPolarHBondContact O-CG 3.29Å; L839-Q843 PolarHBondContact O-N 2.91Å; T841-Q843 VanDerWaalsContact C-N 3.32Å; T841-Q843 PolarHBondContact O-N 3.14Å; Q843-T847 WeakPolarHBondContact O-CB 3.46Å; Q843-T847 PolarHBondContact O-N 3.42Å; Q843-T847 PolarHBondContact O-OG1 3.23Å
844R79.7Confident77.7Confident137 Ų13763.8 Ų63.852%0.51735%0.354SS..Hα-helixtrans-62.9-47.8175.1-74.8-179.8-69.1165.91.9111.5D840 T841 N846 T847 V848D840-R844 VanDerWaalsContact O-CG 3.32Å; D840-R844 WeakPolarHBondContact O-CG 3.47Å; D840-R844 PolarHBondContact O-N 3.18Å; D840-R844 PolarHBondContact O-NE 2.91Å; T841-R844 WeakPolarHBondContact O-CB 3.27Å; T841-R844 PolarHBondContact O-N 3.13Å; T841-R844 PolarHBondContact OG1-NH2 3.09Å; R844-N846 VanDerWaalsContact C-N 3.35Å; R844-N846 PolarHBondContact O-N 3.32Å; R844-T847 WeakPolarHBondContact O-CB 3.31Å; R844-T847 PolarHBondContact O-N 3.13Å; R844-T847 VanDerWaalsContact O-N 3.13Å; R844-V848 WeakPolarHBondContact O-CG2 3.48Å; R844-V848 PolarHBondContact O-N 2.89Å
845D76.1Confident75Confident75 Ų7568.7 Ų68.740%0.40139%0.389SS..Hα-helixtrans-58.5-45.4178.9-69.9-7.3000111.6T841 T847 V848 L849T841-D845 PolarHBondContact O-N 2.73Å; D845-T847 VanDerWaalsContact C-N 3.33Å; D845-T847 PolarHBondContact O-N 3.34Å; D845-V848 PolarHBondContact O-N 3.31Å; D845-L849 WeakPolarHBondContact O-CG 3.47Å; D845-L849 PolarHBondContact O-N 3.35Å
846N70.9Confident72.4Confident107 Ų10771.7 Ų71.757%0.57242%0.42SS*.Hα-helixtrans-63.5-37.5176.8-73.5-22.1000112.6S842 R844 A850S842-N846 VanDerWaalsContact O-CG 3.32Å; S842-N846 PolarHBondContact O-N 3.27Å; S842-N846 VanDerWaalsContact O-N 3.09Å; S842-N846 PolarHBondContact O-ND2 3.14Å; R844-N846 VanDerWaalsContact C-N 3.35Å; R844-N846 PolarHBondContact O-N 3.32Å; N846-A850 WeakPolarHBondContact O-CB 3.43Å; N846-A850 PolarHBondContact O-N 3.05Å
847T69.6Low69.7Low74 Ų7478.4 Ų78.445%0.45446%0.456SS..Hα-helixtrans-68.2-38.9177.5-56.10000111.6Q843 R844 D845 K851Q843-T847 WeakPolarHBondContact O-CB 3.46Å; Q843-T847 PolarHBondContact O-N 3.42Å; Q843-T847 PolarHBondContact O-OG1 3.23Å; R844-T847 WeakPolarHBondContact O-CB 3.31Å; R844-T847 PolarHBondContact O-N 3.13Å; R844-T847 VanDerWaalsContact O-N 3.13Å; D845-T847 VanDerWaalsContact C-N 3.33Å; D845-T847 PolarHBondContact O-N 3.34Å; T847-K851 WeakPolarHBondContact O-CG 3.29Å; T847-K851 PolarHBondContact O-N 3.46Å; T847-K851 VanDerWaalsContact O-N 3.16Å
848V66.6Low66.7Low88 Ų8886.3 Ų86.353%0.53350%0.498SS..Hα-helixtrans-65.6-46175.7173.10000110.4R844 D845 A850 K851 T852R844-V848 WeakPolarHBondContact O-CG2 3.48Å; R844-V848 PolarHBondContact O-N 2.89Å; D845-V848 PolarHBondContact O-N 3.31Å; V848-A850 PolarHBondContact O-N 3.47Å; V848-K851 PolarHBondContact O-N 3.23Å; V848-T852 PolarHBondContact O-N 2.92Å; V848-T852 PolarHBondContact O-OG1 3.48Å; V848-T852 VanDerWaalsContact O-OG1 3.13Å
849L63.7Low63.5Low114 Ų11489.9 Ų89.960%0.59754%0.536SS*.Hα-helixtrans-61.2-40.1176.8-73.9167.8000112.9D845 K851 T852 G853D845-L849 WeakPolarHBondContact O-CG 3.47Å; D845-L849 PolarHBondContact O-N 3.35Å; L849-K851 VanDerWaalsContact C-N 3.35Å; L849-T852 PolarHBondContact O-N 2.73Å; L849-T852 PolarHBondContact O-OG1 3.39Å; L849-G853 PolarHBondContact O-N 3.16Å
850A59.3Low60.3Low65 Ų6598.4 Ų98.454%0.53758%0.575SS.*Hα-helixtrans-64.4-39.4176.300000112N846 V848 D854N846-A850 WeakPolarHBondContact O-CB 3.43Å; N846-A850 PolarHBondContact O-N 3.05Å; V848-A850 PolarHBondContact O-N 3.47Å; A850-D854 PolarHBondContact O-N 3.12Å
851K57.2Low57.4Low156 Ų156103.7 Ų103.768%0.67860%0.602SS**Hα-helixtrans-71.7-31.7178.3-74.1178.7179.2179.80113.5T847 V848 L849T847-K851 WeakPolarHBondContact O-CG 3.29Å; T847-K851 PolarHBondContact O-N 3.46Å; T847-K851 VanDerWaalsContact O-N 3.16Å; V848-K851 PolarHBondContact O-N 3.23Å; L849-K851 VanDerWaalsContact C-N 3.35Å
852T55.7Low54.9Low88 Ų88112.6 Ų112.654%0.5464%0.638SS.*Hα-helixtrans-83.3-22.717753.70000112.8V848 L849 S855V848-T852 PolarHBondContact O-N 2.92Å; V848-T852 PolarHBondContact O-OG1 3.48Å; V848-T852 VanDerWaalsContact O-OG1 3.13Å; L849-T852 PolarHBondContact O-N 2.73Å; L849-T852 PolarHBondContact O-OG1 3.39Å; T852-S855 PolarHBondContact O-OG 3.49Å
853G45.1Very low52.5Low57 Ų57120.7 Ų120.759%0.58869%0.687SS**Hα-helixtrans-74-29.8172.700000114.2L849 S855L849-G853 PolarHBondContact O-N 3.16Å; G853-S855 VanDerWaalsContact C-N 3.34Å
854D47.3Very low51.1Low157 Ų157122.4 Ų122.484%0.8470%0.701SS**THydrogen-bonded Turntrans-83.1-7.3-178.3-126.57.3000113.6A850A850-D854 PolarHBondContact O-N 3.12Å
855S43.4Very low49.6Very low103 Ų103121.6 Ų121.672%0.7271%0.711SS**THydrogen-bonded Turntrans-97.113174.360.90000114.1T852 G853T852-S855 PolarHBondContact O-OG 3.49Å; G853-S855 VanDerWaalsContact C-N 3.34Å
856G43Very low48.1Very low64 Ų64124.2 Ų124.266%0.6673%0.728SS**SBendtrans-112.90.1-170.600000117.7
857D41.3Very low46.7Very low148 Ų148125.2 Ų125.279%0.79174%0.737SS**SBendtrans-152.476.6-177.3-151.410.3000112.6
858N35.7Very low45.3Very low174 Ų174128.4 Ų128.493%0.9376%0.755SS**  trans-169.3105.9154.8-97.5-35000112.3
859G30.6Very low43.9Very low76 Ų76131.1 Ų131.178%0.78477%0.77SS**  trans108.4115.3166.800000112.4
860E30.2Very low42.5Very low192 Ų192132.4 Ų132.490%0.89778%0.782SS**  cis-149.9128.337.1-70.3176.7131.800111.7
861I34.5Very low41.2Very low165 Ų165137.5 Ų137.585%0.84680%0.801SS**  trans-119.7104.6145.8-64173.1000107.2
862K35.8Very low39.9Very low205 Ų205136 Ų13689%0.89181%0.811SS**  trans-125.8110.3142.9-79.7-178.6176.4175.50103.2
863T36Very low38.4Very low203 Ų203140.4 Ų140.4100%1.24584%0.836SS**  -133.5065.344.60000114.5

Retrieved 863 of 863 residues in 2368.9 ms (Link to these results)