A0A087XKL0_POEFO Loading...

Organic cation transporter-like protein 2

May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. Plays a role in the regulation of lipid metabolism.

AlphaFold DB , UniProt , Accession A0A087XKL0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 424 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.4	Very low	37.7	Very low	245 Å²	245	172.9 Å²	172.9	100%	1.207	89%	0.89	S	S	*	*				0	98	0	-126.2	176.7	173.7	0	0	108.9
2	K	36.8	Very low	37.8	Very low	217 Å²	217	168.4 Å²	168.4	94%	0.943	89%	0.885	S	S	*	*			trans	-177.2	96.4	161.2	-110.3	174.7	-179.7	178.7	0	108.4
3	R	34.7	Very low	38.1	Very low	250 Å²	250	160.1 Å²	160.1	94%	0.943	87%	0.865	S	S	*	*	P	Polyproline II helix	trans	-94.3	124.4	164.1	-91.6	-176.2	175.2	-178.6	-1.6	107.3
4	R	36.3	Very low	38.4	Very low	256 Å²	256	157 Å²	157	97%	0.966	85%	0.854	S	S	*	*	P	Polyproline II helix	trans	-67.1	124.6	168	-98.4	175.9	166.4	-176.8	-4.3	108.1
5	G	35.9	Very low	38.8	Very low	69 Å²	69	153.7 Å²	153.7	71%	0.711	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-84	127.5	165.2	0	0	0	0	0	109.6
6	E	38.6	Very low	39	Very low	189 Å²	189	146.7 Å²	146.7	88%	0.883	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-69.9	132.2	166.6	-71.4	169.6	150.1	0	0	109.2
7	T	36.7	Very low	39.4	Very low	141 Å²	141	145.9 Å²	145.9	87%	0.865	81%	0.81	S	S	*	*			trans	-109.7	102.2	167.7	-13.5	0	0	0	0	106.4	A9	T7-A9 PolarHBondContact O-N 3.19Å
8	T	37.7	Very low	40.1	Very low	134 Å²	134	141.9 Å²	141.9	82%	0.822	79%	0.794	S	S	*	*			trans	-71.8	113.1	168.1	33.6	0	0	0	0	108.5
9	A	38.1	Very low	40.9	Very low	97 Å²	97	139.1 Å²	139.1	80%	0.802	78%	0.781	S	S	*	*			trans	-82.7	110	166.9	0	0	0	0	0	108.5	T7	T7-A9 PolarHBondContact O-N 3.19Å
10	E	37.4	Very low	41.9	Very low	180 Å²	180	136.8 Å²	136.8	84%	0.841	77%	0.77	S	S	*	*			trans	-71.5	134.7	162.8	-77	-175.1	156.3	0	0	109.6	S12	E10-S12 PolarHBondContact O-N 3.22Å
11	P	41.8	Very low	43.2	Very low	124 Å²	124	135.2 Å²	135.2	81%	0.805	76%	0.76	S	S	*	*			trans	-77.3	114.3	166.6	30	-27.8	0	0	0	108.7	G13	P11-G13 PolarHBondContact O-N 2.99Å
12	S	39.3	Very low	44.9	Very low	119 Å²	119	128.2 Å²	128.2	83%	0.832	73%	0.731	S	S	*	*			trans	-69.3	73.6	168.6	45.9	0	0	0	0	110.7	E10 T14	E10-S12 PolarHBondContact O-N 3.22Å; S12-T14 PolarHBondContact O-N 3.14Å
13	G	41.4	Very low	46.8	Very low	60 Å²	60	121 Å²	121	62%	0.619	71%	0.712	S	S	*	*			trans	-70.9	107.5	165.1	0	0	0	0	0	109.1	P11 P15	P11-G13 PolarHBondContact O-N 2.99Å; G13-P15 WeakPolarHBondContact O-CD 3.45Å
14	T	42.1	Very low	49	Very low	117 Å²	117	113.6 Å²	113.6	72%	0.718	69%	0.688	S	S	*	*			trans	-63.2	110.3	172.2	22.9	0	0	0	0	109.8	S12 G16	S12-T14 PolarHBondContact O-N 3.14Å; T14-G16 PolarHBondContact O-N 3Å
15	P	44.2	Very low	51.2	Low	108 Å²	108	105 Å²	105	70%	0.701	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.6	-5.2	-175.4	-13.7	30.6	0	0	0	113.9	G13 T19	G13-P15 WeakPolarHBondContact O-CD 3.45Å; P15-T19 PolarHBondContact O-OG1 3.27Å
16	G	41.9	Very low	53.6	Low	41 Å²	41	105.6 Å²	105.6	42%	0.423	65%	0.652	S	S	.	*	H	α-helix	trans	-87.1	-26.6	-170.4	0	0	0	0	0	115.7	T14 T19 T20	T14-G16 PolarHBondContact O-N 3Å; G16-T19 PolarHBondContact O-OG1 3.39Å; G16-T20 PolarHBondContact O-OG1 3.44Å
17	L	46.2	Very low	56	Low	133 Å²	133	103.8 Å²	103.8	70%	0.696	64%	0.642	S	S	*	*	H	α-helix	trans	-80.9	-30.2	-172	-126.8	87.8	0	0	0	113.6
18	S	52.7	Low	58.5	Low	74 Å²	74	100.2 Å²	100.2	52%	0.517	61%	0.614	S	S	.	*	H	α-helix	trans	-80.5	-32.9	-176.3	56.2	0	0	0	0	113.1	T22	S18-T22 PolarHBondContact O-N 3.24Å; S18-T22 PolarHBondContact O-OG1 2.97Å
19	T	55	Low	61.1	Low	89 Å²	89	97.4 Å²	97.4	55%	0.546	59%	0.592	S	S	.	*	H	α-helix	trans	-74.3	-39.3	-178.7	47.4	0	0	0	0	112.3	P15 G16 T22 A23	P15-T19 PolarHBondContact O-OG1 3.27Å; G16-T19 PolarHBondContact O-OG1 3.39Å; T19-T22 PolarHBondContact O-N 3.42Å; T19-A23 PolarHBondContact O-N 2.85Å; T19-A23 VanDerWaalsContact O-N 3.15Å
20	T	60.4	Low	63.8	Low	92 Å²	92	100.5 Å²	100.5	56%	0.564	58%	0.583	S	S	*	*	H	α-helix	trans	-65	-42.1	176.5	-40.8	0	0	0	0	112.1	G16 T22 A23 E24	G16-T20 PolarHBondContact O-OG1 3.44Å; T20-T22 VanDerWaalsContact C-N 3.33Å; T20-T22 PolarHBondContact O-N 2.95Å; T20-A23 PolarHBondContact O-N 2.64Å; T20-E24 PolarHBondContact O-N 3.48Å; T20-E24 VanDerWaalsContact O-N 3.09Å
21	N	70.2	Confident	66.5	Low	105 Å²	105	92.5 Å²	92.5	56%	0.561	55%	0.547	S	S	*	.	H	α-helix	trans	-63.6	-36.8	176	-89.8	-20.3	0	0	0	112.7	Q25	N21-Q25 VanDerWaalsContact O-CB 3.29Å; N21-Q25 WeakPolarHBondContact O-CB 3.43Å; N21-Q25 PolarHBondContact O-N 3.36Å
22	T	74.9	Confident	69	Low	97 Å²	97	86.9 Å²	86.9	60%	0.595	51%	0.51	S	S	*	.	H	α-helix	trans	-70.6	-41.2	-179.8	-53.6	0	0	0	0	111.9	S18 T19 T20 S26	S18-T22 PolarHBondContact O-N 3.24Å; S18-T22 PolarHBondContact O-OG1 2.97Å; T19-T22 PolarHBondContact O-N 3.42Å; T20-T22 VanDerWaalsContact C-N 3.33Å; T20-T22 PolarHBondContact O-N 2.95Å; T22-S26 WeakPolarHBondContact O-CB 3.35Å; T22-S26 PolarHBondContact O-N 3.24Å
23	A	77.9	Confident	71.7	Confident	65 Å²	65	87.8 Å²	87.8	54%	0.537	50%	0.496	S	S	.	.	H	α-helix	trans	-67.6	-40.5	177.3	0	0	0	0	0	112.4	T19 T20 S26 K27	T19-A23 PolarHBondContact O-N 2.85Å; T19-A23 VanDerWaalsContact O-N 3.15Å; T20-A23 PolarHBondContact O-N 2.64Å; A23-S26 PolarHBondContact O-N 2.88Å; A23-K27 WeakPolarHBondContact O-CB 3.46Å; A23-K27 PolarHBondContact O-N 3.45Å
24	E	81.1	Confident	74.4	Confident	95 Å²	95	85.6 Å²	85.6	44%	0.444	47%	0.471	S	S	.	.	H	α-helix	trans	-65.7	-42.1	176.6	-163.5	-170.7	143.9	0	0	111.6	T20 K27 K28	T20-E24 PolarHBondContact O-N 3.48Å; T20-E24 VanDerWaalsContact O-N 3.09Å; E24-K27 WeakPolarHBondContact O-CB 3.35Å; E24-K27 PolarHBondContact O-N 3.16Å; E24-K28 WeakPolarHBondContact O-CG 3.33Å; E24-K28 PolarHBondContact O-N 2.72Å; E24-K28 WeakPolarHBondContact OE1-CE 3.48Å; E24-K28 IonicContact OE1-NZ 2.67Å; E24-K28 PolarHBondContact OE1-NZ 3.31Å
25	Q	82.4	Confident	77	Confident	77 Å²	77	80 Å²	80	36%	0.36	44%	0.436	S	S	.	.	H	α-helix	trans	-64.3	-43.3	176.6	-166	72	-17.4	0	0	111.9	N21 K27 K28 M29	N21-Q25 VanDerWaalsContact O-CB 3.29Å; N21-Q25 WeakPolarHBondContact O-CB 3.43Å; N21-Q25 PolarHBondContact O-N 3.36Å; Q25-K27 VanDerWaalsContact C-N 3.28Å; Q25-K27 PolarHBondContact O-N 3.2Å; Q25-K28 PolarHBondContact O-N 2.9Å; Q25-M29 WeakPolarHBondContact O-CG 3.42Å; Q25-M29 PolarHBondContact O-N 3.29Å
26	S	86.3	Confident	79.5	Confident	81 Å²	81	76.1 Å²	76.1	57%	0.566	41%	0.408	S	S	*	.	H	α-helix	trans	-59	-40.7	174.6	-177.7	0	0	0	0	111.8	T22 A23 M29 R30	T22-S26 WeakPolarHBondContact O-CB 3.35Å; T22-S26 PolarHBondContact O-N 3.24Å; A23-S26 PolarHBondContact O-N 2.88Å; S26-M29 PolarHBondContact O-N 3.34Å; S26-R30 WeakPolarHBondContact O-CB 3.42Å; S26-R30 PolarHBondContact O-N 3.25Å
27	K	88.8	Confident	82.2	Confident	151 Å²	151	78.5 Å²	78.5	66%	0.657	41%	0.41	S	S	*	.	H	α-helix	trans	-64.5	-45	175.3	-171	177.4	-180	-179.9	0	112.2	A23 E24 Q25 R30 V31	A23-K27 WeakPolarHBondContact O-CB 3.46Å; A23-K27 PolarHBondContact O-N 3.45Å; E24-K27 WeakPolarHBondContact O-CB 3.35Å; E24-K27 PolarHBondContact O-N 3.16Å; Q25-K27 VanDerWaalsContact C-N 3.28Å; Q25-K27 PolarHBondContact O-N 3.2Å; K27-R30 WeakPolarHBondContact O-CB 3.46Å; K27-R30 PolarHBondContact O-N 2.85Å; K27-V31 WeakPolarHBondContact O-CG2 3.35Å; K27-V31 PolarHBondContact O-N 3.02Å
28	K	89.4	Confident	84.7	Confident	66 Å²	66	72.1 Å²	72.1	29%	0.287	38%	0.377	S	S	.	.	H	α-helix	trans	-59.7	-46.3	175.9	-72.3	175.1	-175.7	161.9	0	111.4	E24 Q25 R30 V31 I32 L144	E24-K28 WeakPolarHBondContact O-CG 3.33Å; E24-K28 PolarHBondContact O-N 2.72Å; E24-K28 WeakPolarHBondContact OE1-CE 3.48Å; E24-K28 IonicContact OE1-NZ 2.67Å; E24-K28 PolarHBondContact OE1-NZ 3.31Å; Q25-K28 PolarHBondContact O-N 2.9Å; K28-R30 VanDerWaalsContact C-N 3.34Å; K28-R30 PolarHBondContact O-N 3.05Å; K28-V31 PolarHBondContact O-N 3.04Å; K28-V31 VanDerWaalsContact O-N 3.16Å; K28-I32 WeakPolarHBondContact O-CG1 3.33Å; K28-I32 PolarHBondContact O-N 3.11Å; K28-L144 HydrophobicContact CG-CD2 4.47Å
29	M	90.8	Very high	86.8	Confident	75 Å²	75	68.6 Å²	68.6	37%	0.369	35%	0.352	S	S	.	.	H	α-helix	trans	-60.5	-43.3	176.9	-71.3	-54.7	-58.4	0	0	112	Q25 S26 V31 I32 Y33	Q25-M29 WeakPolarHBondContact O-CG 3.42Å; Q25-M29 PolarHBondContact O-N 3.29Å; S26-M29 PolarHBondContact O-N 3.34Å; M29-V31 VanDerWaalsContact C-N 3.31Å; M29-V31 PolarHBondContact O-N 2.91Å; M29-I32 PolarHBondContact O-N 3.12Å; M29-I32 HydrophobicContact SD-CD1 4.37Å; M29-Y33 HydrophobicContact CB-CE2 4.35Å; M29-Y33 HydrophobicContact CE-CE2 3.94Å; M29-Y33 WeakPolarHBondContact O-CD2 3.46Å; M29-Y33 PolarHBondContact O-N 3.16Å
30	R	94.5	Very high	88.8	Confident	161 Å²	161	65.4 Å²	65.4	61%	0.608	33%	0.333	S	S	*	.	H	α-helix	trans	-57.8	-43.5	174.7	-173.1	-179.4	-178.3	-179.9	3.8	111.9	S26 K27 K28 Y33 V34	S26-R30 WeakPolarHBondContact O-CB 3.42Å; S26-R30 PolarHBondContact O-N 3.25Å; K27-R30 WeakPolarHBondContact O-CB 3.46Å; K27-R30 PolarHBondContact O-N 2.85Å; K28-R30 VanDerWaalsContact C-N 3.34Å; K28-R30 PolarHBondContact O-N 3.05Å; R30-Y33 PolarHBondContact O-N 3.07Å; R30-V34 WeakPolarHBondContact O-CG2 3.45Å; R30-V34 PolarHBondContact O-N 3.29Å
31	V	95.4	Very high	90.6	Very high	12 Å²	12	62.7 Å²	62.7	7%	0.073	32%	0.315	C	S	.	.	H	α-helix	trans	-62.7	-45.1	177	177.1	0	0	0	0	110.9	K27 K28 M29 Y33 V34 V35 V140 L144 I203	K27-V31 WeakPolarHBondContact O-CG2 3.35Å; K27-V31 PolarHBondContact O-N 3.02Å; K28-V31 PolarHBondContact O-N 3.04Å; K28-V31 VanDerWaalsContact O-N 3.16Å; M29-V31 VanDerWaalsContact C-N 3.31Å; M29-V31 PolarHBondContact O-N 2.91Å; V31-Y33 PolarHBondContact O-N 3.49Å; V31-V34 PolarHBondContact O-N 3.03Å; V31-V34 VanDerWaalsContact O-N 3.16Å; V31-V35 WeakPolarHBondContact O-CG2 3.04Å; V31-V35 PolarHBondContact O-N 3.35Å; V31-V140 HydrophobicContact CG1-CG1 4.2Å; V31-L144 HydrophobicContact CB-CD1 3.84Å; V31-L144 HydrophobicContact CG1-CD1 3.39Å; V31-I203 HydrophobicContact CG1-CD1 3.76Å
32	I	94.7	Very high	91.9	Very high	7 Å²	7	58.7 Å²	58.7	4%	0.036	29%	0.294	C	S	.	.	H	α-helix	trans	-60.1	-43.8	177.8	-68.5	168.4	0	0	0	111.2	K28 M29 V34 V35 Y36 L144	K28-I32 WeakPolarHBondContact O-CG1 3.33Å; K28-I32 PolarHBondContact O-N 3.11Å; M29-I32 PolarHBondContact O-N 3.12Å; M29-I32 HydrophobicContact SD-CD1 4.37Å; I32-V34 VanDerWaalsContact C-N 3.34Å; I32-V34 PolarHBondContact O-N 2.95Å; I32-V35 WeakPolarHBondContact O-CB 3.31Å; I32-V35 PolarHBondContact O-N 3.03Å; I32-V35 VanDerWaalsContact O-N 3.13Å; I32-Y36 HydrophobicContact CG2-CD2 4.26Å; I32-Y36 HydrophobicContact CG2-CE1 4.2Å; I32-Y36 HydrophobicContact CG2-CE2 3.55Å; I32-Y36 VanDerWaalsContact CG2-CZ 3.5Å; I32-Y36 WeakPolarHBondContact CG2-OH 3.34Å; I32-Y36 PolarHBondContact O-N 2.97Å; I32-L144 HydrophobicContact CD1-CB 4.14Å; I32-L144 HydrophobicContact CG1-CB 4.16Å; I32-L144 HydrophobicContact CG1-CD1 4.46Å
33	Y	96.2	Very high	92.9	Very high	137 Å²	137	54.2 Å²	54.2	54%	0.537	27%	0.266	S	S	.	.	H	α-helix	trans	-61.8	-40.7	175	-74.4	-61.4	0	0	0	112.5	M29 R30 V31 V35 Y36 I37	M29-Y33 HydrophobicContact CB-CE2 4.35Å; M29-Y33 HydrophobicContact CE-CE2 3.94Å; M29-Y33 WeakPolarHBondContact O-CD2 3.46Å; M29-Y33 PolarHBondContact O-N 3.16Å; R30-Y33 PolarHBondContact O-N 3.07Å; V31-Y33 PolarHBondContact O-N 3.49Å; Y33-V35 VanDerWaalsContact C-N 3.28Å; Y33-V35 PolarHBondContact O-N 3.47Å; Y33-Y36 HydrophobicContact CD1-CD2 4.12Å; Y33-Y36 WeakPolarHBondContact O-CB 3.19Å; Y33-Y36 PolarHBondContact O-N 2.74Å; Y33-I37 WeakPolarHBondContact O-CG1 3.19Å; Y33-I37 PolarHBondContact O-N 3Å
34	V	97.2	Very high	93.9	Very high	14 Å²	14	51.8 Å²	51.8	9%	0.085	24%	0.244	C	C	.	.	H	α-helix	trans	-63.6	-37.2	174.5	174.2	0	0	0	0	111.1	R30 V31 I32 I37 I38 L198 F202	R30-V34 WeakPolarHBondContact O-CG2 3.45Å; R30-V34 PolarHBondContact O-N 3.29Å; V31-V34 PolarHBondContact O-N 3.03Å; V31-V34 VanDerWaalsContact O-N 3.16Å; I32-V34 VanDerWaalsContact C-N 3.34Å; I32-V34 PolarHBondContact O-N 2.95Å; V34-I37 WeakPolarHBondContact O-CB 3.48Å; V34-I37 PolarHBondContact O-N 3.29Å; V34-I38 HydrophobicContact CG1-CD1 3.79Å; V34-I38 HydrophobicContact CG1-CG1 4.32Å; V34-I38 VanDerWaalsContact O-CG1 3.31Å; V34-I38 WeakPolarHBondContact O-CG1 3.32Å; V34-I38 PolarHBondContact O-N 3.05Å; V34-L198 HydrophobicContact CG1-CB 4.41Å; V34-F202 HydrophobicContact CB-CB 4.24Å; V34-F202 HydrophobicContact CG1-CB 3.75Å; V34-F202 HydrophobicContact CG1-CD2 4.26Å; V34-F202 HydrophobicContact CG1-CG 4.15Å; V34-F202 HydrophobicContact CG2-CB 4.09Å; V34-F202 HydrophobicContact CG2-CD1 4.24Å; V34-F202 HydrophobicContact CG2-CG 4.03Å
35	V	96.9	Very high	94.6	Very high	0 Å²	0	48.3 Å²	48.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-62	-42.5	173.6	174	0	0	0	0	111.3	V31 I32 Y33 I37 I38 V39 C137 V140 V141 I203	V31-V35 WeakPolarHBondContact O-CG2 3.04Å; V31-V35 PolarHBondContact O-N 3.35Å; I32-V35 WeakPolarHBondContact O-CB 3.31Å; I32-V35 PolarHBondContact O-N 3.03Å; I32-V35 VanDerWaalsContact O-N 3.13Å; Y33-V35 VanDerWaalsContact C-N 3.28Å; Y33-V35 PolarHBondContact O-N 3.47Å; V35-I37 VanDerWaalsContact C-N 3.3Å; V35-I37 PolarHBondContact O-N 3.23Å; V35-I38 PolarHBondContact O-N 3.04Å; V35-V39 HydrophobicContact CG1-CG2 4.37Å; V35-V39 WeakPolarHBondContact O-CG2 3.2Å; V35-V39 PolarHBondContact O-N 2.88Å; V35-C137 HydrophobicContact CG1-CB 3.57Å; V35-V140 HydrophobicContact CG2-CB 4.06Å; V35-V140 HydrophobicContact CG2-CG1 3.64Å; V35-V141 HydrophobicContact CB-CG2 4.38Å; V35-V141 HydrophobicContact CG1-CG2 3.75Å; V35-I203 HydrophobicContact CG2-CD1 3.63Å
36	Y	97.4	Very high	95.2	Very high	26 Å²	26	47.1 Å²	47.1	10%	0.102	22%	0.222	C	C	.	.	H	α-helix	trans	-60.8	-38.3	174.4	-63.7	-30.4	0	0	0	112.8	I32 Y33 S40 V141 A153 K156 L157 C160	I32-Y36 HydrophobicContact CG2-CD2 4.26Å; I32-Y36 HydrophobicContact CG2-CE1 4.2Å; I32-Y36 HydrophobicContact CG2-CE2 3.55Å; I32-Y36 VanDerWaalsContact CG2-CZ 3.5Å; I32-Y36 WeakPolarHBondContact CG2-OH 3.34Å; I32-Y36 PolarHBondContact O-N 2.97Å; Y33-Y36 HydrophobicContact CD1-CD2 4.12Å; Y33-Y36 WeakPolarHBondContact O-CB 3.19Å; Y33-Y36 PolarHBondContact O-N 2.74Å; Y36-S40 WeakPolarHBondContact O-CB 3.48Å; Y36-S40 PolarHBondContact O-N 2.93Å; Y36-S40 PolarHBondContact O-OG 3.23Å; Y36-V141 HydrophobicContact CE1-CG2 4.34Å; Y36-A153 WeakPolarHBondContact OH-CA 3.4Å; Y36-A153 PolarHBondContact OH-O 3.05Å; Y36-K156 HydrophobicContact CE1-CB 4Å; Y36-K156 HydrophobicContact CE2-CB 4.28Å; Y36-K156 HydrophobicContact CE2-CD 4.08Å; Y36-L157 HydrophobicContact CD1-CD2 3.69Å; Y36-L157 HydrophobicContact CE1-CD2 3.82Å; Y36-L157 HydrophobicContact CE1-CG 4.37Å; Y36-C160 PolarHBondContact O-SG 3.47Å; Y36-C160 VanDerWaalsContact O-SG 3.4Å
37	I	97.9	Very high	95.6	Very high	91 Å²	91	44 Å²	44	47%	0.467	20%	0.199	S	C	.	.	H	α-helix	trans	-63.9	-48.8	173.4	-66.1	168.8	0	0	0	110.3	Y33 V34 V35 V39 S40 L41 L198	Y33-I37 WeakPolarHBondContact O-CG1 3.19Å; Y33-I37 PolarHBondContact O-N 3Å; V34-I37 WeakPolarHBondContact O-CB 3.48Å; V34-I37 PolarHBondContact O-N 3.29Å; V35-I37 VanDerWaalsContact C-N 3.3Å; V35-I37 PolarHBondContact O-N 3.23Å; I37-V39 VanDerWaalsContact C-N 3.3Å; I37-V39 PolarHBondContact O-N 2.85Å; I37-S40 PolarHBondContact O-N 3.31Å; I37-S40 VanDerWaalsContact O-N 3.15Å; I37-L41 HydrophobicContact CG2-CD1 3.98Å; I37-L41 HydrophobicContact CG2-CG 4.3Å; I37-L41 WeakPolarHBondContact O-CG 3.31Å; I37-L41 PolarHBondContact O-N 3.4Å; I37-L198 HydrophobicContact CG2-CD1 4.05Å
38	I	97.9	Very high	96	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-57.6	-43.7	178.8	-69.8	161.2	0	0	0	111	V34 V35 L41 D42 L98 V133 L198 V199 I203	V34-I38 HydrophobicContact CG1-CD1 3.79Å; V34-I38 HydrophobicContact CG1-CG1 4.32Å; V34-I38 VanDerWaalsContact O-CG1 3.31Å; V34-I38 WeakPolarHBondContact O-CG1 3.32Å; V34-I38 PolarHBondContact O-N 3.05Å; V35-I38 PolarHBondContact O-N 3.04Å; I38-L41 PolarHBondContact O-N 3.45Å; I38-D42 WeakPolarHBondContact O-CB 3.38Å; I38-D42 PolarHBondContact O-N 3.06Å; I38-L98 HydrophobicContact CD1-CD2 4.43Å; I38-L98 HydrophobicContact CG2-CD1 4.43Å; I38-V133 HydrophobicContact CG2-CG1 4.2Å; I38-L198 HydrophobicContact CD1-CB 4.14Å; I38-L198 HydrophobicContact CG1-CB 4.01Å; I38-L198 HydrophobicContact CG1-CD1 4.22Å; I38-V199 HydrophobicContact CD1-CG2 3.73Å; I38-V199 HydrophobicContact CG1-CG2 4.47Å; I38-V199 HydrophobicContact CG2-CG2 4.46Å; I38-I203 HydrophobicContact CD1-CD1 4.28Å; I38-I203 HydrophobicContact CD1-CG1 4.37Å
39	V	97.3	Very high	96.2	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-64.1	-44.8	177.1	172.5	0	0	0	0	111	V35 I37 L41 D42 I43 L134 C137 L157 C160	V35-V39 HydrophobicContact CG1-CG2 4.37Å; V35-V39 WeakPolarHBondContact O-CG2 3.2Å; V35-V39 PolarHBondContact O-N 2.88Å; I37-V39 VanDerWaalsContact C-N 3.3Å; I37-V39 PolarHBondContact O-N 2.85Å; V39-L41 VanDerWaalsContact C-N 3.29Å; V39-L41 PolarHBondContact O-N 3.16Å; V39-D42 PolarHBondContact O-N 3.05Å; V39-I43 HydrophobicContact CG1-CG1 4.35Å; V39-I43 VanDerWaalsContact O-CG1 3.29Å; V39-I43 WeakPolarHBondContact O-CG1 3.25Å; V39-I43 PolarHBondContact O-N 3.31Å; V39-L134 HydrophobicContact CG1-CD1 3.9Å; V39-L134 HydrophobicContact CG2-CD1 4.39Å; V39-C137 HydrophobicContact CG2-CB 3.35Å; V39-C137 WeakPolarHBondContact CG2-SG 3.09Å; V39-L157 HydrophobicContact CB-CD2 4.39Å; V39-L157 HydrophobicContact CG1-CD2 4.32Å; V39-L157 HydrophobicContact CG2-CD2 3.95Å; V39-C160 HydrophobicContact CB-CB 4.24Å; V39-C160 HydrophobicContact CG1-CB 3.75Å
40	S	97.4	Very high	96.2	Very high	21 Å²	21	33.7 Å²	33.7	15%	0.147	15%	0.152	C	C	.	.	H	α-helix	trans	-61	-41	178.3	-53.5	0	0	0	0	111.3	Y36 I37 T44 C160	Y36-S40 WeakPolarHBondContact O-CB 3.48Å; Y36-S40 PolarHBondContact O-N 2.93Å; Y36-S40 PolarHBondContact O-OG 3.23Å; I37-S40 PolarHBondContact O-N 3.31Å; I37-S40 VanDerWaalsContact O-N 3.15Å; S40-T44 WeakPolarHBondContact O-CB 3.42Å; S40-T44 PolarHBondContact O-N 3.4Å; S40-T44 PolarHBondContact O-OG1 3.1Å; S40-C160 VanDerWaalsContact OG-CB 3.28Å; S40-C160 WeakPolarHBondContact OG-CB 3.39Å; S40-C160 PolarHBondContact OG-SG 2.88Å; S40-C160 VanDerWaalsContact OG-SG 3.4Å
41	L	97.9	Very high	96	Very high	35 Å²	35	26 Å²	26	18%	0.183	12%	0.123	C	C	.	.	H	α-helix	trans	-66.8	-47.4	175.7	-68.9	177.3	0	0	0	111.8	I37 I38 V39 I43 T44 W45 F194 L198	I37-L41 HydrophobicContact CG2-CD1 3.98Å; I37-L41 HydrophobicContact CG2-CG 4.3Å; I37-L41 WeakPolarHBondContact O-CG 3.31Å; I37-L41 PolarHBondContact O-N 3.4Å; I38-L41 PolarHBondContact O-N 3.45Å; V39-L41 VanDerWaalsContact C-N 3.29Å; V39-L41 PolarHBondContact O-N 3.16Å; L41-I43 VanDerWaalsContact C-N 3.33Å; L41-I43 PolarHBondContact O-N 3.33Å; L41-T44 CarbonylContact O-C 3.53Å; L41-T44 WeakPolarHBondContact O-CA 3.33Å; L41-T44 VanDerWaalsContact O-CB 3.22Å; L41-T44 WeakPolarHBondContact O-CB 3.37Å; L41-T44 PolarHBondContact O-N 3.06Å; L41-W45 HydrophobicContact CB-CZ2 4.32Å; L41-W45 HydrophobicContact CD2-CH2 4.41Å; L41-W45 HydrophobicContact CD2-CZ2 3.77Å; L41-W45 PolarHBondContact O-N 2.84Å; L41-W45 PolarHBondContact O-NE1 3.24Å; L41-F194 HydrophobicContact CD1-CD1 4.06Å; L41-F194 HydrophobicContact CD1-CE1 4.19Å; L41-L198 HydrophobicContact CD1-CD1 3.87Å
42	D	97.3	Very high	95.9	Very high	21 Å²	21	25.5 Å²	25.5	11%	0.112	12%	0.12	C	C	.	.	H	α-helix	trans	-57.2	-46.2	178.2	-179.8	67.7	0	0	0	112.2	I38 V39 T44 W45 M46 V133	I38-D42 WeakPolarHBondContact O-CB 3.38Å; I38-D42 PolarHBondContact O-N 3.06Å; V39-D42 PolarHBondContact O-N 3.05Å; D42-T44 VanDerWaalsContact C-N 3.32Å; D42-T44 PolarHBondContact O-N 3.44Å; D42-W45 PolarHBondContact O-N 3.21Å; D42-M46 WeakPolarHBondContact O-CB 3.49Å; D42-M46 PolarHBondContact O-N 2.93Å; D42-V133 HydrophobicContact CB-CB 4.2Å; D42-V133 HydrophobicContact CB-CG1 3.71Å; D42-V133 VanDerWaalsContact CG-CB 3.44Å; D42-V133 WeakPolarHBondContact OD1-CB 3.49Å; D42-V133 VanDerWaalsContact OD1-CG2 3.29Å; D42-V133 WeakPolarHBondContact OD1-CG2 3.44Å; D42-V133 WeakPolarHBondContact OD2-CB 3.49Å
43	I	96.4	Very high	95.8	Very high	4 Å²	4	25.2 Å²	25.2	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-65.8	-36.7	175.7	-59.8	-56.9	0	0	0	111	V39 L41 W45 M46 F47 F161	V39-I43 HydrophobicContact CG1-CG1 4.35Å; V39-I43 VanDerWaalsContact O-CG1 3.29Å; V39-I43 WeakPolarHBondContact O-CG1 3.25Å; V39-I43 PolarHBondContact O-N 3.31Å; L41-I43 VanDerWaalsContact C-N 3.33Å; L41-I43 PolarHBondContact O-N 3.33Å; I43-W45 VanDerWaalsContact C-N 3.33Å; I43-W45 PolarHBondContact O-N 3.46Å; I43-M46 HydrophobicContact CD1-CE 3.9Å; I43-M46 HydrophobicContact CD1-SD 4.47Å; I43-M46 HydrophobicContact CG2-CE 4.22Å; I43-M46 PolarHBondContact O-N 3.31Å; I43-F47 HydrophobicContact CG2-CD2 3.58Å; I43-F47 HydrophobicContact CG2-CE2 3.72Å; I43-F47 WeakPolarHBondContact O-CD2 3.34Å; I43-F47 PolarHBondContact O-N 2.97Å; I43-F161 HydrophobicContact CD1-CD2 3.51Å; I43-F161 HydrophobicContact CD1-CE2 3.72Å; I43-F161 HydrophobicContact CG1-CD2 3.8Å; I43-F161 HydrophobicContact CG1-CE2 4.43Å; I43-F161 HydrophobicContact CG2-CD2 4.01Å; I43-F161 HydrophobicContact CG2-CE2 4.31Å; I43-F161 HydrophobicContact CG2-CG 4.29Å; I43-F161 WeakPolarHBondContact CG2-O 3.36Å
44	T	97.8	Very high	95.6	Very high	13 Å²	13	19 Å²	19	8%	0.08	10%	0.095	C	C	.	.	H	α-helix	trans	-56.8	-47.1	171.8	-59.5	0	0	0	0	111.2	S40 L41 D42 F47 L48 G164 A167 G168 L171	S40-T44 WeakPolarHBondContact O-CB 3.42Å; S40-T44 PolarHBondContact O-N 3.4Å; S40-T44 PolarHBondContact O-OG1 3.1Å; L41-T44 CarbonylContact O-C 3.53Å; L41-T44 WeakPolarHBondContact O-CA 3.33Å; L41-T44 VanDerWaalsContact O-CB 3.22Å; L41-T44 WeakPolarHBondContact O-CB 3.37Å; L41-T44 PolarHBondContact O-N 3.06Å; D42-T44 VanDerWaalsContact C-N 3.32Å; D42-T44 PolarHBondContact O-N 3.44Å; T44-F47 PolarHBondContact O-N 3.24Å; T44-L48 WeakPolarHBondContact O-CB 3.37Å; T44-L48 PolarHBondContact O-N 3.39Å; T44-G164 WeakPolarHBondContact CA-O 3.31Å; T44-G164 WeakPolarHBondContact OG1-CA 3.45Å; T44-A167 HydrophobicContact CG2-CB 4.16Å; T44-G168 WeakPolarHBondContact O-CA 3.49Å; T44-L171 HydrophobicContact CG2-CD2 4.45Å
45	W	97.3	Very high	95.5	Very high	23 Å²	23	19.4 Å²	19.4	9%	0.087	10%	0.095	C	C	.	.	H	α-helix	trans	-68.5	-41.6	179.7	-47.1	139.3	0	0	0	111.5	L41 D42 I43 F47 L48 Q49 F109 L171 G191 S195	L41-W45 HydrophobicContact CB-CZ2 4.32Å; L41-W45 HydrophobicContact CD2-CH2 4.41Å; L41-W45 HydrophobicContact CD2-CZ2 3.77Å; L41-W45 PolarHBondContact O-N 2.84Å; L41-W45 PolarHBondContact O-NE1 3.24Å; D42-W45 PolarHBondContact O-N 3.21Å; I43-W45 VanDerWaalsContact C-N 3.33Å; I43-W45 PolarHBondContact O-N 3.46Å; W45-F47 VanDerWaalsContact C-N 3.35Å; W45-F47 PolarHBondContact O-N 2.93Å; W45-L48 HydrophobicContact CE3-CD1 4.49Å; W45-L48 WeakPolarHBondContact O-CB 3.41Å; W45-L48 PolarHBondContact O-N 2.94Å; W45-Q49 PolarHBondContact O-N 2.88Å; W45-F109 HydrophobicContact CB-CE2 3.76Å; W45-F109 HydrophobicContact CB-CZ 4.02Å; W45-F109 WeakPolarHBondContact O-CZ 3.32Å; W45-L171 HydrophobicContact CZ3-CD2 3.95Å; W45-G191 VanDerWaalsContact CE2-C 3.46Å; W45-G191 PolarHBondContact NE1-O 3.44Å; W45-S195 PolarHBondContact NE1-OG 3.19Å
46	M	95	Very high	95.3	Very high	52 Å²	52	19.7 Å²	19.7	26%	0.256	10%	0.096	S	C	.	.	H	α-helix	trans	-56.5	-46.8	174.9	-175.4	-174.5	70.6	0	0	112	D42 I43 Q49 F50 F161	D42-M46 WeakPolarHBondContact O-CB 3.49Å; D42-M46 PolarHBondContact O-N 2.93Å; I43-M46 HydrophobicContact CD1-CE 3.9Å; I43-M46 HydrophobicContact CD1-SD 4.47Å; I43-M46 HydrophobicContact CG2-CE 4.22Å; I43-M46 PolarHBondContact O-N 3.31Å; M46-Q49 WeakPolarHBondContact O-CB 3.24Å; M46-Q49 PolarHBondContact O-N 3.06Å; M46-F50 HydrophobicContact CE-CE2 4.09Å; M46-F50 HydrophobicContact CG-CD2 4.47Å; M46-F50 HydrophobicContact CG-CE1 4.36Å; M46-F50 HydrophobicContact CG-CE2 3.88Å; M46-F50 HydrophobicContact CG-CZ 3.81Å; M46-F50 WeakPolarHBondContact O-CG 3.42Å; M46-F50 PolarHBondContact O-N 2.98Å; M46-F50 HydrophobicContact SD-CE2 4.14Å; M46-F50 HydrophobicContact SD-CZ 4.13Å; M46-F161 HydrophobicContact CE-CE2 4.04Å; M46-F161 HydrophobicContact CE-CZ 4.32Å
47	F	94.9	Very high	95.2	Very high	16 Å²	16	18.4 Å²	18.4	7%	0.07	9%	0.092	C	C	.	.	H	α-helix	trans	-74.2	-31.3	179.1	-84	-80.5	0	0	0	113.4	I43 T44 W45 Q49 F50 S51 F161 M165 S169	I43-F47 HydrophobicContact CG2-CD2 3.58Å; I43-F47 HydrophobicContact CG2-CE2 3.72Å; I43-F47 WeakPolarHBondContact O-CD2 3.34Å; I43-F47 PolarHBondContact O-N 2.97Å; T44-F47 PolarHBondContact O-N 3.24Å; W45-F47 VanDerWaalsContact C-N 3.35Å; W45-F47 PolarHBondContact O-N 2.93Å; F47-Q49 VanDerWaalsContact C-N 3.29Å; F47-Q49 PolarHBondContact O-N 3.3Å; F47-F50 AromaticContact CD1-CD2 3.88Å; F47-F50 HydrophobicContact CD1-CD2 3.88Å; F47-F50 AromaticContact CE1-CD2 3.93Å; F47-F50 HydrophobicContact CE1-CD2 3.93Å; F47-F50 HydrophobicContact CE1-CE2 4.41Å; F47-F50 HydrophobicContact CG-CD2 4.39Å; F47-F50 HydrophobicContact CZ-CD2 4.49Å; F47-F50 PolarHBondContact O-N 3.31Å; F47-S51 PolarHBondContact O-N 3.37Å; F47-S51 PolarHBondContact O-OG 3.22Å; F47-F161 HydrophobicContact CE2-CE1 4.32Å; F47-F161 HydrophobicContact CE2-CE2 4.49Å; F47-F161 HydrophobicContact CE2-CZ 4.01Å; F47-F161 HydrophobicContact CZ-CE1 4.46Å; F47-F161 HydrophobicContact CZ-CZ 4.24Å; F47-M165 HydrophobicContact CD1-CB 4.43Å; F47-M165 HydrophobicContact CD1-CG 3.7Å; F47-M165 VanDerWaalsContact CD2-CA 3.46Å; F47-M165 HydrophobicContact CD2-CB 3.77Å; F47-M165 HydrophobicContact CD2-CG 3.93Å; F47-M165 HydrophobicContact CE1-CB 4.34Å; F47-M165 HydrophobicContact CE1-CE 4.11Å; F47-M165 HydrophobicContact CE1-CG 3.48Å; F47-M165 VanDerWaalsContact CE1-CG 3.48Å; F47-M165 HydrophobicContact CE1-SD 3.78Å; F47-M165 HydrophobicContact CE2-CB 3.62Å; F47-M165 HydrophobicContact CE2-CE 3.85Å; F47-M165 HydrophobicContact CE2-CG 3.7Å; F47-M165 HydrophobicContact CE2-SD 4.35Å; F47-M165 HydrophobicContact CG-CB 4.18Å; F47-M165 HydrophobicContact CG-CG 3.93Å; F47-M165 HydrophobicContact CZ-CB 3.96Å; F47-M165 HydrophobicContact CZ-CE 3.38Å; F47-M165 HydrophobicContact CZ-CG 3.5Å; F47-M165 VanDerWaalsContact CZ-CG 3.5Å; F47-M165 HydrophobicContact CZ-SD 3.68Å; F47-S169 WeakPolarHBondContact CD1-OG 3.29Å
48	L	96.3	Very high	95	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-57.4	-46.4	166.5	178.7	152	0	0	0	110	T44 W45 F50 S51 V52 F109 G168 L171 V187	T44-L48 WeakPolarHBondContact O-CB 3.37Å; T44-L48 PolarHBondContact O-N 3.39Å; W45-L48 HydrophobicContact CE3-CD1 4.49Å; W45-L48 WeakPolarHBondContact O-CB 3.41Å; W45-L48 PolarHBondContact O-N 2.94Å; L48-F50 VanDerWaalsContact C-N 3.33Å; L48-F50 PolarHBondContact O-N 2.97Å; L48-S51 PolarHBondContact O-N 3.04Å; L48-S51 VanDerWaalsContact O-N 3.16Å; L48-V52 HydrophobicContact CD2-CG2 3.89Å; L48-V52 HydrophobicContact CG-CG2 4.24Å; L48-V52 WeakPolarHBondContact O-CB 3.37Å; L48-V52 WeakPolarHBondContact O-CG2 3.48Å; L48-V52 PolarHBondContact O-N 2.68Å; L48-F109 HydrophobicContact CD2-CE1 3.74Å; L48-F109 HydrophobicContact CD2-CZ 4.21Å; L48-G168 WeakPolarHBondContact CA-O 3.47Å; L48-G168 PolarHBondContact N-O 3.49Å; L48-L171 HydrophobicContact CD1-CD2 4.06Å; L48-L171 HydrophobicContact CD1-CG 4.25Å; L48-V187 HydrophobicContact CD1-CG1 4.44Å
49	Q	94.5	Very high	94.7	Very high	8 Å²	8	25.4 Å²	25.4	4%	0.037	12%	0.119	C	C	.	.	H	α-helix	trans	-61.7	-39.7	177.4	-171.1	175.9	13.1	0	0	112.1	W45 M46 F47 S51 V52 T53 F109 L112 H124	W45-Q49 PolarHBondContact O-N 2.88Å; M46-Q49 WeakPolarHBondContact O-CB 3.24Å; M46-Q49 PolarHBondContact O-N 3.06Å; F47-Q49 VanDerWaalsContact C-N 3.29Å; F47-Q49 PolarHBondContact O-N 3.3Å; Q49-S51 VanDerWaalsContact C-N 3.31Å; Q49-S51 PolarHBondContact O-N 2.67Å; Q49-V52 PolarHBondContact O-N 3.26Å; Q49-T53 WeakPolarHBondContact CG-OG1 3.23Å; Q49-T53 VanDerWaalsContact O-CB 3.31Å; Q49-T53 WeakPolarHBondContact O-CB 3.34Å; Q49-T53 PolarHBondContact O-N 3.49Å; Q49-T53 PolarHBondContact O-OG1 3.5Å; Q49-F109 HydrophobicContact CB-CE1 3.98Å; Q49-F109 HydrophobicContact CB-CZ 3.82Å; Q49-F109 HydrophobicContact CG-CE1 4.38Å; Q49-F109 HydrophobicContact CG-CZ 4.48Å; Q49-L112 HydrophobicContact CG-CD2 4.35Å; Q49-H124 PolarHBondContact NE2-CE1 3.14Å
50	F	90.9	Very high	94.6	Very high	66 Å²	66	27.1 Å²	27.1	29%	0.289	13%	0.127	S	C	.	.	H	α-helix	trans	-66	-29.8	175.6	-68	-17.6	0	0	0	113.6	M46 F47 L48 P54	M46-F50 HydrophobicContact CE-CE2 4.09Å; M46-F50 HydrophobicContact CG-CD2 4.47Å; M46-F50 HydrophobicContact CG-CE1 4.36Å; M46-F50 HydrophobicContact CG-CE2 3.88Å; M46-F50 HydrophobicContact CG-CZ 3.81Å; M46-F50 WeakPolarHBondContact O-CG 3.42Å; M46-F50 PolarHBondContact O-N 2.98Å; M46-F50 HydrophobicContact SD-CE2 4.14Å; M46-F50 HydrophobicContact SD-CZ 4.13Å; F47-F50 AromaticContact CD1-CD2 3.88Å; F47-F50 HydrophobicContact CD1-CD2 3.88Å; F47-F50 AromaticContact CE1-CD2 3.93Å; F47-F50 HydrophobicContact CE1-CD2 3.93Å; F47-F50 HydrophobicContact CE1-CE2 4.41Å; F47-F50 HydrophobicContact CG-CD2 4.39Å; F47-F50 HydrophobicContact CZ-CD2 4.49Å; F47-F50 PolarHBondContact O-N 3.31Å; L48-F50 VanDerWaalsContact C-N 3.33Å; L48-F50 PolarHBondContact O-N 2.97Å; F50-P54 WeakPolarHBondContact O-CD 3.28Å; F50-P54 VanDerWaalsContact O-CG 3.26Å; F50-P54 WeakPolarHBondContact O-CG 3.36Å
51	S	90.4	Very high	94.3	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.007	15%	0.151	C	C	.	.	H	α-helix	trans	-78.2	-30.9	173	-67.2	0	0	0	0	113.1	F47 L48 Q49 Y55 S169	F47-S51 PolarHBondContact O-N 3.37Å; F47-S51 PolarHBondContact O-OG 3.22Å; L48-S51 PolarHBondContact O-N 3.04Å; L48-S51 VanDerWaalsContact O-N 3.16Å; Q49-S51 VanDerWaalsContact C-N 3.31Å; Q49-S51 PolarHBondContact O-N 2.67Å; S51-Y55 WeakPolarHBondContact O-CD2 3.32Å; S51-S169 PolarHBondContact OG-O 3.36Å
52	V	92.1	Very high	94.1	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-90.9	-49.5	-172.7	176.8	0	0	0	0	112.5	L48 Q49 P54 Y55 L56 S176 E181 A184	L48-V52 HydrophobicContact CD2-CG2 3.89Å; L48-V52 HydrophobicContact CG-CG2 4.24Å; L48-V52 WeakPolarHBondContact O-CB 3.37Å; L48-V52 WeakPolarHBondContact O-CG2 3.48Å; L48-V52 PolarHBondContact O-N 2.68Å; Q49-V52 PolarHBondContact O-N 3.26Å; V52-P54 VanDerWaalsContact C-CD 3.45Å; V52-Y55 PolarHBondContact O-N 3.15Å; V52-L56 PolarHBondContact O-N 3.22Å; V52-L56 VanDerWaalsContact O-N 3.15Å; V52-S176 VanDerWaalsContact CG2-OG 3.26Å; V52-S176 WeakPolarHBondContact CG2-OG 3.48Å; V52-E181 HydrophobicContact CG1-CB 3.73Å; V52-E181 HydrophobicContact CG1-CG 4.25Å; V52-A184 HydrophobicContact CG1-CB 4.32Å; V52-A184 HydrophobicContact CG2-CB 3.53Å
53	T	93.7	Very high	93.9	Very high	2 Å²	2	30.5 Å²	30.5	1%	0.012	16%	0.158	C	C	.	.	H	α-helix	trans	-57.4	-42.8	-169.4	-48.8	0	0	0	0	113.5	Q49 Y55 L56 A57 F67 L70	Q49-T53 WeakPolarHBondContact CG-OG1 3.23Å; Q49-T53 VanDerWaalsContact O-CB 3.31Å; Q49-T53 WeakPolarHBondContact O-CB 3.34Å; Q49-T53 PolarHBondContact O-N 3.49Å; Q49-T53 PolarHBondContact O-OG1 3.5Å; T53-Y55 VanDerWaalsContact C-N 3.32Å; T53-Y55 PolarHBondContact O-N 3.17Å; T53-L56 PolarHBondContact O-N 2.97Å; T53-A57 VanDerWaalsContact O-CB 3.24Å; T53-A57 WeakPolarHBondContact O-CB 3.41Å; T53-A57 PolarHBondContact O-N 2.85Å; T53-F67 HydrophobicContact CG2-CE2 4.25Å; T53-L70 HydrophobicContact CG2-CD2 4.29Å
54	P	92.3	Very high	93.6	Very high	5 Å²	5	30.8 Å²	30.8	3%	0.032	16%	0.16	C	C	.	.	H	α-helix	trans	-57.7	-44.9	179.2	-23	33.5	0	0	0	112.6	F50 V52 A57 K58 F67 M266	F50-P54 WeakPolarHBondContact O-CD 3.28Å; F50-P54 VanDerWaalsContact O-CG 3.26Å; F50-P54 WeakPolarHBondContact O-CG 3.36Å; V52-P54 VanDerWaalsContact C-CD 3.45Å; P54-A57 PolarHBondContact O-N 3.33Å; P54-K58 PolarHBondContact O-N 3.19Å; P54-F67 VanDerWaalsContact CA-CE2 3.48Å; P54-F67 HydrophobicContact CB-CE2 4.07Å; P54-F67 HydrophobicContact CB-CZ 3.98Å; P54-F67 HydrophobicContact CG-CE2 4.16Å; P54-F67 HydrophobicContact CG-CZ 3.72Å; P54-M266 HydrophobicContact CB-CE 3.26Å; P54-M266 WeakPolarHBondContact O-CE 3.36Å
55	Y	93.3	Very high	93.3	Very high	24 Å²	24	31.9 Å²	31.9	9%	0.094	17%	0.165	C	C	.	.	H	α-helix	trans	-70.7	-42.6	-176.4	-68.7	-93.5	0	0	0	111.5	S51 V52 T53 A57 K58 K59 M266 L271 E272 A273 N276	S51-Y55 WeakPolarHBondContact O-CD2 3.32Å; V52-Y55 PolarHBondContact O-N 3.15Å; T53-Y55 VanDerWaalsContact C-N 3.32Å; T53-Y55 PolarHBondContact O-N 3.17Å; Y55-A57 VanDerWaalsContact C-N 3.33Å; Y55-A57 PolarHBondContact O-N 3.47Å; Y55-K58 PolarHBondContact O-N 3.45Å; Y55-K59 WeakPolarHBondContact O-CB 3.31Å; Y55-K59 PolarHBondContact O-N 2.93Å; Y55-M266 HydrophobicContact CD1-CE 4.15Å; Y55-M266 HydrophobicContact CD1-CG 4.11Å; Y55-M266 HydrophobicContact CD1-SD 3.9Å; Y55-M266 HydrophobicContact CD2-CE 3.97Å; Y55-M266 HydrophobicContact CE1-CB 4.36Å; Y55-M266 HydrophobicContact CE1-CE 4.24Å; Y55-M266 HydrophobicContact CE1-CG 3.67Å; Y55-M266 HydrophobicContact CE1-SD 4.06Å; Y55-M266 HydrophobicContact CE2-CE 4.06Å; Y55-M266 HydrophobicContact CG-CE 4.01Å; Y55-M266 HydrophobicContact CG-SD 4.27Å; Y55-L271 VanDerWaalsContact CE1-O 3.28Å; Y55-L271 WeakPolarHBondContact CE1-O 3.47Å; Y55-L271 PolarHBondContact OH-O 3.4Å; Y55-E272 PolarHBondContact OH-O 3.29Å; Y55-A273 HydrophobicContact CD1-CB 4.12Å; Y55-A273 HydrophobicContact CD2-CB 3.94Å; Y55-A273 HydrophobicContact CE1-CB 4.12Å; Y55-A273 HydrophobicContact CE2-CB 3.96Å; Y55-A273 HydrophobicContact CG-CB 4.03Å; Y55-A273 VanDerWaalsContact CZ-CA 3.42Å; Y55-N276 HydrophobicContact CE2-CB 4.2Å; Y55-N276 WeakPolarHBondContact OH-CB 3.42Å
56	L	94.3	Very high	93.1	Very high	5 Å²	5	37 Å²	37	3%	0.026	19%	0.185	C	C	.	.	H	α-helix	trans	-62.8	-41	173.7	-176.6	59.3	0	0	0	111.6	V52 T53 K58 K59 L60 L112 A115 L121 E181	V52-L56 PolarHBondContact O-N 3.22Å; V52-L56 VanDerWaalsContact O-N 3.15Å; T53-L56 PolarHBondContact O-N 2.97Å; L56-K58 PolarHBondContact O-N 3.09Å; L56-K59 WeakPolarHBondContact O-CB 3.45Å; L56-K59 PolarHBondContact O-N 3.38Å; L56-L60 HydrophobicContact CD1-CD1 4.23Å; L56-L60 HydrophobicContact CD1-CG 4.3Å; L56-L60 HydrophobicContact CG-CD1 4.12Å; L56-L60 WeakPolarHBondContact O-CG 3.44Å; L56-L60 PolarHBondContact O-N 3.43Å; L56-L112 HydrophobicContact CD2-CD1 3.65Å; L56-L112 HydrophobicContact CD2-CG 4.33Å; L56-A115 HydrophobicContact CD2-CB 4.39Å; L56-L121 HydrophobicContact CD2-CD2 4.41Å; L56-L121 HydrophobicContact CG-CD2 4.45Å; L56-E181 HydrophobicContact CB-CB 3.99Å; L56-E181 HydrophobicContact CB-CG 4.11Å; L56-E181 HydrophobicContact CD1-CB 4.24Å; L56-E181 HydrophobicContact CG-CB 4.49Å
57	A	94.6	Very high	93	Very high	0 Å²	0	35 Å²	35	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-61.1	-45.6	177.8	0	0	0	0	0	111.9	T53 P54 Y55 K59 L60 G61 F62 F67 L121	T53-A57 VanDerWaalsContact O-CB 3.24Å; T53-A57 WeakPolarHBondContact O-CB 3.41Å; T53-A57 PolarHBondContact O-N 2.85Å; P54-A57 PolarHBondContact O-N 3.33Å; Y55-A57 VanDerWaalsContact C-N 3.33Å; Y55-A57 PolarHBondContact O-N 3.47Å; A57-K59 PolarHBondContact O-N 3.38Å; A57-L60 CarbonylContact O-C 3.53Å; A57-L60 PolarHBondContact O-N 3.01Å; A57-G61 PolarHBondContact O-N 3.38Å; A57-F62 HydrophobicContact CB-CB 4.13Å; A57-F62 HydrophobicContact CB-CD2 3.96Å; A57-F62 HydrophobicContact CB-CG 4.15Å; A57-F62 WeakPolarHBondContact O-CB 3.23Å; A57-F62 PolarHBondContact O-N 2.95Å; A57-F67 HydrophobicContact CB-CD2 3.64Å; A57-F67 HydrophobicContact CB-CE2 4.07Å; A57-L121 HydrophobicContact CB-CD1 3.8Å
58	K	92.8	Very high	92.9	Very high	90 Å²	90	34.3 Å²	34.3	39%	0.391	17%	0.171	S	C	.	.	H	α-helix	trans	-61.6	-42.6	174.7	-174	171.7	-177.2	169.1	0	112.2	P54 Y55 L56 L60 G61 M266 D267	P54-K58 PolarHBondContact O-N 3.19Å; Y55-K58 PolarHBondContact O-N 3.45Å; L56-K58 PolarHBondContact O-N 3.09Å; K58-L60 PolarHBondContact O-N 2.96Å; K58-G61 PolarHBondContact O-N 3.5Å; K58-M266 HydrophobicContact CB-SD 3.87Å; K58-M266 HydrophobicContact CD-CG 4.13Å; K58-M266 HydrophobicContact CD-SD 3.23Å; K58-M266 WeakPolarHBondContact CD-SD 3.32Å; K58-M266 HydrophobicContact CG-SD 4.21Å; K58-D267 IonicContact NZ-OD1 3.61Å; K58-D267 PolarHBondContact NZ-OD1 2.9Å
59	K	92.6	Very high	92.9	Very high	148 Å²	148	38.7 Å²	38.7	64%	0.643	19%	0.189	S	C	*	.	H	α-helix	trans	-60.7	-32.8	176	-174.7	179.1	-178.3	178.4	0	112.7	Y55 L56 A57 G61 E181	Y55-K59 WeakPolarHBondContact O-CB 3.31Å; Y55-K59 PolarHBondContact O-N 2.93Å; L56-K59 WeakPolarHBondContact O-CB 3.45Å; L56-K59 PolarHBondContact O-N 3.38Å; A57-K59 PolarHBondContact O-N 3.38Å; K59-G61 VanDerWaalsContact C-N 3.27Å; K59-E181 IonicContact NZ-OE2 2.73Å
60	L	94.8	Very high	92.9	Very high	35 Å²	35	38.3 Å²	38.3	18%	0.183	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.1	5.4	175.4	-66.5	177	0	0	0	113.5	L56 A57 K58 N116 P118 L121	L56-L60 HydrophobicContact CD1-CD1 4.23Å; L56-L60 HydrophobicContact CD1-CG 4.3Å; L56-L60 HydrophobicContact CG-CD1 4.12Å; L56-L60 WeakPolarHBondContact O-CG 3.44Å; L56-L60 PolarHBondContact O-N 3.43Å; A57-L60 CarbonylContact O-C 3.53Å; A57-L60 PolarHBondContact O-N 3.01Å; K58-L60 PolarHBondContact O-N 2.96Å; L60-N116 WeakPolarHBondContact CD2-O 3.35Å; L60-P118 WeakPolarHBondContact O-CG 3.34Å; L60-L121 HydrophobicContact CB-CD1 4.22Å; L60-L121 HydrophobicContact CD1-CD1 3.88Å; L60-L121 HydrophobicContact CD1-CD2 4Å; L60-L121 HydrophobicContact CD1-CG 3.89Å
61	G	92.4	Very high	93	Very high	63 Å²	63	36.9 Å²	36.9	65%	0.649	18%	0.181	S	C	*	.	T	Hydrogen-bonded Turn	trans	94	14.4	172.3	0	0	0	0	0	115.5	A57 K58 K59	A57-G61 PolarHBondContact O-N 3.38Å; K58-G61 PolarHBondContact O-N 3.5Å; K59-G61 VanDerWaalsContact C-N 3.27Å
62	F	93.5	Very high	93.2	Very high	18 Å²	18	37.9 Å²	37.9	8%	0.079	19%	0.187	C	C	.	.			trans	-72.1	132.7	172.4	-78.9	22.7	0	0	0	110.4	A57 W66 F67 L70 P118 L121 F122	A57-F62 HydrophobicContact CB-CB 4.13Å; A57-F62 HydrophobicContact CB-CD2 3.96Å; A57-F62 HydrophobicContact CB-CG 4.15Å; A57-F62 WeakPolarHBondContact O-CB 3.23Å; A57-F62 PolarHBondContact O-N 2.95Å; F62-W66 HydrophobicContact CB-CB 4.17Å; F62-W66 HydrophobicContact CD1-CB 4.39Å; F62-W66 HydrophobicContact CD2-CB 4Å; F62-W66 HydrophobicContact CE2-CB 4.5Å; F62-W66 HydrophobicContact CG-CB 3.95Å; F62-F67 HydrophobicContact CD2-CB 4.42Å; F62-L70 HydrophobicContact CE2-CB 4.03Å; F62-L70 HydrophobicContact CE2-CD2 3.99Å; F62-L70 HydrophobicContact CE2-CG 4.45Å; F62-P118 HydrophobicContact CE1-CB 3.7Å; F62-P118 HydrophobicContact CE1-CG 4.24Å; F62-L121 HydrophobicContact CD1-CD1 4.09Å; F62-L121 HydrophobicContact CD2-CD1 4.13Å; F62-L121 HydrophobicContact CE1-CD1 3.75Å; F62-L121 HydrophobicContact CE2-CB 4.23Å; F62-L121 HydrophobicContact CE2-CD1 3.79Å; F62-L121 HydrophobicContact CG-CD1 4.27Å; F62-L121 HydrophobicContact CZ-CB 3.98Å; F62-L121 HydrophobicContact CZ-CD1 3.59Å; F62-L121 HydrophobicContact CZ-CG 4.41Å; F62-F122 AromaticContact CE2-CE2 3.95Å; F62-F122 HydrophobicContact CE2-CE2 3.95Å; F62-F122 HydrophobicContact CE2-CZ 4.39Å; F62-F122 HydrophobicContact CZ-CD2 4.08Å; F62-F122 AromaticContact CZ-CE2 3.51Å; F62-F122 HydrophobicContact CZ-CE2 3.51Å; F62-F122 HydrophobicContact CZ-CZ 4.36Å
63	D	91.4	Very high	93.3	Very high	67 Å²	67	39.9 Å²	39.9	36%	0.358	20%	0.2	S	C	.	.			trans	-81.9	178.1	159.6	67.4	18.9	0	0	0	110.9	L65 W66 F67 M389	D63-L65 VanDerWaalsContact C-N 3.27Å; D63-L65 PolarHBondContact O-N 3.02Å; D63-L65 PolarHBondContact OD1-N 3.47Å; D63-W66 PolarHBondContact O-N 3.45Å; D63-W66 WeakPolarHBondContact OD1-CB 3.39Å; D63-W66 VanDerWaalsContact OD1-CD1 3.24Å; D63-W66 PolarHBondContact OD1-N 2.95Å; D63-F67 PolarHBondContact O-N 2.89Å; D63-M389 HydrophobicContact CB-CE 4.37Å; D63-M389 HydrophobicContact CB-SD 4.48Å
64	T	90.4	Very high	93.3	Very high	11 Å²	11	40.5 Å²	40.5	7%	0.067	20%	0.203	C	C	.	.	H	α-helix	trans	-56.7	-37.9	179	-51.9	0	0	0	0	112.6	G68 I263 D267 Y388 M389	T64-G68 PolarHBondContact O-N 3.32Å; T64-I263 HydrophobicContact CG2-CD1 3.88Å; T64-I263 HydrophobicContact CG2-CG2 3.67Å; T64-D267 PolarHBondContact OG1-OD2 3.36Å; T64-Y388 HydrophobicContact CG2-CD1 3.65Å; T64-Y388 HydrophobicContact CG2-CE1 4.43Å; T64-Y388 HydrophobicContact CG2-CG 4.22Å; T64-M389 HydrophobicContact CG2-CG 4.13Å
65	L	92.1	Very high	93.2	Very high	35 Å²	35	40.4 Å²	40.4	18%	0.183	20%	0.203	C	C	.	.	H	α-helix	trans	-75	-43.2	-177.1	-174.5	66	0	0	0	111.7	D63 F67 G68 Y69 F386 M389	D63-L65 VanDerWaalsContact C-N 3.27Å; D63-L65 PolarHBondContact O-N 3.02Å; D63-L65 PolarHBondContact OD1-N 3.47Å; L65-F67 VanDerWaalsContact C-N 3.31Å; L65-F67 PolarHBondContact O-N 3.5Å; L65-G68 CarbonylContact O-C 3.19Å; L65-G68 VanDerWaalsContact O-CA 3.31Å; L65-G68 WeakPolarHBondContact O-CA 3.31Å; L65-G68 PolarHBondContact O-N 2.81Å; L65-Y69 HydrophobicContact CD1-CE1 4.25Å; L65-Y69 HydrophobicContact CD1-CE2 4.48Å; L65-Y69 HydrophobicContact CD2-CE2 4.11Å; L65-Y69 HydrophobicContact CG-CD2 4.45Å; L65-Y69 HydrophobicContact CG-CE1 4.4Å; L65-Y69 HydrophobicContact CG-CE2 3.76Å; L65-Y69 PolarHBondContact O-N 3.03Å; L65-F386 HydrophobicContact CD1-CB 4.28Å; L65-M389 HydrophobicContact CB-SD 3.42Å; L65-M389 WeakPolarHBondContact CB-SD 3.41Å; L65-M389 PolarHBondContact N-SD 3.47Å; L65-M389 VanDerWaalsContact N-SD 3.39Å
66	W	93.9	Very high	93.3	Very high	132 Å²	132	43.5 Å²	43.5	50%	0.5	22%	0.221	S	C	.	.	H	α-helix	trans	-62.5	-37.9	174.3	-82.1	106.9	0	0	0	112.2	F62 D63 G68 Y69 L70 F122	F62-W66 HydrophobicContact CB-CB 4.17Å; F62-W66 HydrophobicContact CD1-CB 4.39Å; F62-W66 HydrophobicContact CD2-CB 4Å; F62-W66 HydrophobicContact CE2-CB 4.5Å; F62-W66 HydrophobicContact CG-CB 3.95Å; D63-W66 PolarHBondContact O-N 3.45Å; D63-W66 WeakPolarHBondContact OD1-CB 3.39Å; D63-W66 VanDerWaalsContact OD1-CD1 3.24Å; D63-W66 PolarHBondContact OD1-N 2.95Å; W66-G68 VanDerWaalsContact C-N 3.33Å; W66-Y69 HydrophobicContact CD2-CD2 4.21Å; W66-Y69 AromaticContact CE3-CD2 3.9Å; W66-Y69 HydrophobicContact CE3-CD2 3.9Å; W66-Y69 HydrophobicContact CZ3-CD2 4.27Å; W66-Y69 PolarHBondContact O-N 2.98Å; W66-L70 PolarHBondContact O-N 2.81Å; W66-F122 HydrophobicContact CE3-CE2 4.43Å; W66-F122 HydrophobicContact CE3-CZ 4.25Å; W66-F122 HydrophobicContact CZ3-CZ 4.47Å
67	F	92.7	Very high	93.3	Very high	10 Å²	10	44.6 Å²	44.6	4%	0.044	23%	0.226	C	C	.	.	H	α-helix	trans	-65.6	-37.4	170.5	-171.1	-90.9	0	0	0	112.1	T53 P54 A57 F62 D63 L65 L70 Q71 I263	T53-F67 HydrophobicContact CG2-CE2 4.25Å; P54-F67 VanDerWaalsContact CA-CE2 3.48Å; P54-F67 HydrophobicContact CB-CE2 4.07Å; P54-F67 HydrophobicContact CB-CZ 3.98Å; P54-F67 HydrophobicContact CG-CE2 4.16Å; P54-F67 HydrophobicContact CG-CZ 3.72Å; A57-F67 HydrophobicContact CB-CD2 3.64Å; A57-F67 HydrophobicContact CB-CE2 4.07Å; F62-F67 HydrophobicContact CD2-CB 4.42Å; D63-F67 PolarHBondContact O-N 2.89Å; L65-F67 VanDerWaalsContact C-N 3.31Å; L65-F67 PolarHBondContact O-N 3.5Å; F67-L70 HydrophobicContact CD2-CD2 4.31Å; F67-L70 HydrophobicContact CE2-CD2 4.36Å; F67-L70 WeakPolarHBondContact O-CB 3.38Å; F67-L70 PolarHBondContact O-N 3.31Å; F67-Q71 HydrophobicContact CD1-CG 3.94Å; F67-Q71 HydrophobicContact CE1-CG 3.51Å; F67-Q71 HydrophobicContact CZ-CG 3.92Å; F67-Q71 WeakPolarHBondContact O-CG 3.28Å; F67-Q71 PolarHBondContact O-N 2.87Å; F67-I263 HydrophobicContact CB-CD1 4.26Å; F67-I263 HydrophobicContact CD1-CD1 3.47Å; F67-I263 VanDerWaalsContact CD1-CD1 3.47Å; F67-I263 HydrophobicContact CD1-CG1 3.63Å; F67-I263 HydrophobicContact CE1-CD1 4.23Å; F67-I263 HydrophobicContact CE1-CG1 4.01Å; F67-I263 HydrophobicContact CG-CD1 4.23Å; F67-I263 HydrophobicContact CG-CG1 4.4Å
68	G	93.1	Very high	93.2	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-54.9	-50.9	169.4	0	0	0	0	0	112.2	T64 L65 W66 L70 Q71 T72	T64-G68 PolarHBondContact O-N 3.32Å; L65-G68 CarbonylContact O-C 3.19Å; L65-G68 VanDerWaalsContact O-CA 3.31Å; L65-G68 WeakPolarHBondContact O-CA 3.31Å; L65-G68 PolarHBondContact O-N 2.81Å; W66-G68 VanDerWaalsContact C-N 3.33Å; G68-L70 VanDerWaalsContact C-N 3.32Å; G68-L70 PolarHBondContact O-N 3.41Å; G68-Q71 PolarHBondContact O-N 3.46Å; G68-T72 WeakPolarHBondContact O-CB 3.46Å; G68-T72 PolarHBondContact O-N 3.43Å; G68-T72 PolarHBondContact O-OG1 3.36Å
69	Y	94.7	Very high	93	Very high	93 Å²	93	47.1 Å²	47.1	37%	0.365	24%	0.242	S	C	.	.	H	α-helix	trans	-60.7	-38.4	176.7	-64	-35.9	0	0	0	113.1	L65 W66 T72 T73 T382	L65-Y69 HydrophobicContact CD1-CE1 4.25Å; L65-Y69 HydrophobicContact CD1-CE2 4.48Å; L65-Y69 HydrophobicContact CD2-CE2 4.11Å; L65-Y69 HydrophobicContact CG-CD2 4.45Å; L65-Y69 HydrophobicContact CG-CE1 4.4Å; L65-Y69 HydrophobicContact CG-CE2 3.76Å; L65-Y69 PolarHBondContact O-N 3.03Å; W66-Y69 HydrophobicContact CD2-CD2 4.21Å; W66-Y69 AromaticContact CE3-CD2 3.9Å; W66-Y69 HydrophobicContact CE3-CD2 3.9Å; W66-Y69 HydrophobicContact CZ3-CD2 4.27Å; W66-Y69 PolarHBondContact O-N 2.98Å; Y69-T72 PolarHBondContact O-N 3.49Å; Y69-T73 WeakPolarHBondContact O-CB 3.3Å; Y69-T73 PolarHBondContact O-N 2.9Å; Y69-T73 PolarHBondContact O-OG1 3.49Å; Y69-T382 HydrophobicContact CD1-CG2 3.95Å; Y69-T382 HydrophobicContact CE1-CG2 3.6Å
70	L	94.5	Very high	92.8	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-59.2	-50.1	174.5	180	65.3	0	0	0	111.2	T53 F62 W66 F67 G68 T72 T73 V74 L121 F122 K125	T53-L70 HydrophobicContact CG2-CD2 4.29Å; F62-L70 HydrophobicContact CE2-CB 4.03Å; F62-L70 HydrophobicContact CE2-CD2 3.99Å; F62-L70 HydrophobicContact CE2-CG 4.45Å; W66-L70 PolarHBondContact O-N 2.81Å; F67-L70 HydrophobicContact CD2-CD2 4.31Å; F67-L70 HydrophobicContact CE2-CD2 4.36Å; F67-L70 WeakPolarHBondContact O-CB 3.38Å; F67-L70 PolarHBondContact O-N 3.31Å; G68-L70 VanDerWaalsContact C-N 3.32Å; G68-L70 PolarHBondContact O-N 3.41Å; L70-T72 PolarHBondContact O-N 3.36Å; L70-T73 WeakPolarHBondContact O-CB 3.35Å; L70-T73 PolarHBondContact O-N 2.83Å; L70-V74 WeakPolarHBondContact O-CG2 3.38Å; L70-V74 PolarHBondContact O-N 3.44Å; L70-V74 VanDerWaalsContact O-N 3.15Å; L70-L121 HydrophobicContact CD1-CB 4.23Å; L70-L121 WeakPolarHBondContact CD1-O 3.21Å; L70-L121 HydrophobicContact CD2-CB 4.11Å; L70-F122 HydrophobicContact CB-CE1 4.19Å; L70-F122 HydrophobicContact CB-CZ 4.22Å; L70-F122 HydrophobicContact CD1-CB 4.47Å; L70-F122 HydrophobicContact CD1-CD1 3.79Å; L70-F122 HydrophobicContact CD1-CD2 4.3Å; L70-F122 HydrophobicContact CD1-CE1 4.04Å; L70-F122 HydrophobicContact CD1-CG 3.93Å; L70-F122 HydrophobicContact CD1-CZ 4.39Å; L70-K125 HydrophobicContact CD1-CG 3.86Å
71	Q	93.1	Very high	92.5	Very high	36 Å²	36	43.6 Å²	43.6	17%	0.168	23%	0.23	C	C	.	.	H	α-helix	trans	-67.8	-36.2	-179.6	-64.9	-73.7	71.5	0	0	112.1	F67 G68 T73 V74 G75 P381	F67-Q71 HydrophobicContact CD1-CG 3.94Å; F67-Q71 HydrophobicContact CE1-CG 3.51Å; F67-Q71 HydrophobicContact CZ-CG 3.92Å; F67-Q71 WeakPolarHBondContact O-CG 3.28Å; F67-Q71 PolarHBondContact O-N 2.87Å; G68-Q71 PolarHBondContact O-N 3.46Å; Q71-T73 VanDerWaalsContact C-N 3.32Å; Q71-T73 PolarHBondContact O-N 3.35Å; Q71-V74 WeakPolarHBondContact O-CB 3.34Å; Q71-V74 PolarHBondContact O-N 3.05Å; Q71-G75 PolarHBondContact O-N 3.17Å; Q71-G75 VanDerWaalsContact O-N 3.09Å; Q71-P381 HydrophobicContact CB-CB 3.62Å; Q71-P381 HydrophobicContact CB-CG 3.63Å; Q71-P381 HydrophobicContact CG-CB 4.49Å
72	T	94.3	Very high	92.2	Very high	22 Å²	22	41.9 Å²	41.9	14%	0.135	21%	0.212	C	C	.	.	H	α-helix	trans	-61.1	-41.3	171.6	-67	0	0	0	0	111.9	G68 Y69 L70 V74 G75 L76 T378 T382	G68-T72 WeakPolarHBondContact O-CB 3.46Å; G68-T72 PolarHBondContact O-N 3.43Å; G68-T72 PolarHBondContact O-OG1 3.36Å; Y69-T72 PolarHBondContact O-N 3.49Å; L70-T72 PolarHBondContact O-N 3.36Å; T72-V74 VanDerWaalsContact C-N 3.3Å; T72-V74 PolarHBondContact O-N 2.91Å; T72-G75 PolarHBondContact O-N 2.57Å; T72-G75 VanDerWaalsContact O-N 3.12Å; T72-L76 HydrophobicContact CG2-CD1 4.34Å; T72-L76 WeakPolarHBondContact O-CG 3.27Å; T72-L76 PolarHBondContact O-N 3.11Å; T72-T378 WeakPolarHBondContact CA-O 3.31Å; T72-T378 WeakPolarHBondContact CB-O 3.4Å; T72-T378 HydrophobicContact CG2-CG2 4.28Å; T72-T378 VanDerWaalsContact CG2-O 3.25Å; T72-T378 WeakPolarHBondContact CG2-O 3.45Å; T72-T378 PolarHBondContact OG1-O 2.97Å; T72-T382 WeakPolarHBondContact CB-OG1 3.08Å; T72-T382 PolarHBondContact OG1-OG1 3.19Å
73	T	94.7	Very high	91.7	Very high	42 Å²	42	43.6 Å²	43.6	26%	0.258	23%	0.225	S	C	.	.	H	α-helix	trans	-60.3	-40.8	175.4	-58.3	0	0	0	0	111.3	Y69 L70 Q71 G75 L76 I77 F122	Y69-T73 WeakPolarHBondContact O-CB 3.3Å; Y69-T73 PolarHBondContact O-N 2.9Å; Y69-T73 PolarHBondContact O-OG1 3.49Å; L70-T73 WeakPolarHBondContact O-CB 3.35Å; L70-T73 PolarHBondContact O-N 2.83Å; Q71-T73 VanDerWaalsContact C-N 3.32Å; Q71-T73 PolarHBondContact O-N 3.35Å; T73-G75 VanDerWaalsContact C-N 3.35Å; T73-G75 PolarHBondContact O-N 3.11Å; T73-L76 PolarHBondContact O-N 2.94Å; T73-I77 HydrophobicContact CG2-CD1 3.7Å; T73-I77 HydrophobicContact CG2-CG1 4.31Å; T73-I77 WeakPolarHBondContact O-CB 3.2Å; T73-I77 VanDerWaalsContact O-CG1 3.23Å; T73-I77 WeakPolarHBondContact O-CG1 3.09Å; T73-I77 PolarHBondContact O-N 3.32Å; T73-F122 HydrophobicContact CG2-CD1 4.23Å
74	V	93.4	Very high	91.6	Very high	14 Å²	14	45.1 Å²	45.1	9%	0.085	23%	0.231	C	C	.	.	H	α-helix	trans	-59.2	-46.1	173.3	-176	0	0	0	0	111.6	L70 Q71 T72 L76 I77 Q78 K125 T128	L70-V74 WeakPolarHBondContact O-CG2 3.38Å; L70-V74 PolarHBondContact O-N 3.44Å; L70-V74 VanDerWaalsContact O-N 3.15Å; Q71-V74 WeakPolarHBondContact O-CB 3.34Å; Q71-V74 PolarHBondContact O-N 3.05Å; T72-V74 VanDerWaalsContact C-N 3.3Å; T72-V74 PolarHBondContact O-N 2.91Å; V74-L76 PolarHBondContact O-N 3.27Å; V74-I77 PolarHBondContact O-N 3.32Å; V74-Q78 HydrophobicContact CG1-CG 4.34Å; V74-Q78 WeakPolarHBondContact O-CB 3.44Å; V74-Q78 WeakPolarHBondContact O-CG 3.22Å; V74-Q78 PolarHBondContact O-N 3.45Å; V74-K125 HydrophobicContact CG2-CB 3.95Å; V74-K125 HydrophobicContact CG2-CD 3.35Å; V74-K125 HydrophobicContact CG2-CG 3.55Å; V74-T128 HydrophobicContact CG1-CG2 4.19Å
75	G	91.6	Very high	91.5	Very high	3 Å²	3	44.9 Å²	44.9	3%	0.031	23%	0.229	C	C	.	.	H	α-helix	trans	-58.4	-46.3	178.1	0	0	0	0	0	112.4	Q71 T72 T73 Q78 L79 T378	Q71-G75 PolarHBondContact O-N 3.17Å; Q71-G75 VanDerWaalsContact O-N 3.09Å; T72-G75 PolarHBondContact O-N 2.57Å; T72-G75 VanDerWaalsContact O-N 3.12Å; T73-G75 VanDerWaalsContact C-N 3.35Å; T73-G75 PolarHBondContact O-N 3.11Å; G75-Q78 PolarHBondContact O-N 3.2Å; G75-L79 VanDerWaalsContact O-CB 3.29Å; G75-L79 WeakPolarHBondContact O-CB 3.41Å; G75-L79 PolarHBondContact O-N 3.27Å; G75-T378 VanDerWaalsContact CA-OG1 3.26Å; G75-T378 WeakPolarHBondContact CA-OG1 3.44Å
76	L	93.7	Very high	91.1	Very high	90 Å²	90	44.6 Å²	44.6	47%	0.471	23%	0.234	S	C	.	.	H	α-helix	trans	-63.2	-46.2	177.4	-68.6	173.9	0	0	0	112.3	T72 T73 V74 Q78 L79 I80 T378	T72-L76 HydrophobicContact CG2-CD1 4.34Å; T72-L76 WeakPolarHBondContact O-CG 3.27Å; T72-L76 PolarHBondContact O-N 3.11Å; T73-L76 PolarHBondContact O-N 2.94Å; V74-L76 PolarHBondContact O-N 3.27Å; L76-Q78 PolarHBondContact O-N 2.78Å; L76-L79 PolarHBondContact O-N 3.48Å; L76-I80 WeakPolarHBondContact O-CG1 3.17Å; L76-I80 PolarHBondContact O-N 2.85Å; L76-T378 HydrophobicContact CD2-CG2 3.77Å; L76-T378 HydrophobicContact CG-CG2 3.79Å
77	I	95.3	Very high	90.6	Very high	27 Å²	27	46.8 Å²	46.8	14%	0.138	24%	0.242	C	C	.	.	H	α-helix	trans	-61.8	-45.3	178.8	-68.4	168.7	0	0	0	110.5	T73 V74 I80 G81 L126 T128 V129	T73-I77 HydrophobicContact CG2-CD1 3.7Å; T73-I77 HydrophobicContact CG2-CG1 4.31Å; T73-I77 WeakPolarHBondContact O-CB 3.2Å; T73-I77 VanDerWaalsContact O-CG1 3.23Å; T73-I77 WeakPolarHBondContact O-CG1 3.09Å; T73-I77 PolarHBondContact O-N 3.32Å; V74-I77 PolarHBondContact O-N 3.32Å; I77-I80 PolarHBondContact O-N 3.23Å; I77-G81 PolarHBondContact O-N 2.97Å; I77-L126 HydrophobicContact CD1-CD2 4.06Å; I77-T128 WeakPolarHBondContact CG2-OG1 3.41Å; I77-V129 HydrophobicContact CG2-CB 3.62Å; I77-V129 HydrophobicContact CG2-CG2 4.37Å; I77-V129 VanDerWaalsContact CG2-N 3.33Å
78	Q	92.1	Very high	90.4	Very high	40 Å²	40	49 Å²	49	19%	0.187	25%	0.252	C	S	.	.	H	α-helix	trans	-70.4	-30.3	178.4	-73.4	-175.4	17.7	0	0	113.3	V74 G75 L76 I80 G81 G82	V74-Q78 HydrophobicContact CG1-CG 4.34Å; V74-Q78 WeakPolarHBondContact O-CB 3.44Å; V74-Q78 WeakPolarHBondContact O-CG 3.22Å; V74-Q78 PolarHBondContact O-N 3.45Å; G75-Q78 PolarHBondContact O-N 3.2Å; L76-Q78 PolarHBondContact O-N 2.78Å; Q78-I80 VanDerWaalsContact C-N 3.32Å; Q78-G81 PolarHBondContact O-N 3.38Å; Q78-G82 PolarHBondContact O-N 2.97Å
79	L	87.9	Confident	90.1	Very high	104 Å²	104	49 Å²	49	55%	0.545	25%	0.252	S	S	.	.	H	α-helix	trans	-63.4	-40.9	175.6	-176.5	66.3	0	0	0	111	G75 L76 P83	G75-L79 VanDerWaalsContact O-CB 3.29Å; G75-L79 WeakPolarHBondContact O-CB 3.41Å; G75-L79 PolarHBondContact O-N 3.27Å; L76-L79 PolarHBondContact O-N 3.48Å; L79-P83 VanDerWaalsContact O-CD 3.25Å; L79-P83 WeakPolarHBondContact O-CD 3.41Å
80	I	88.6	Confident	89.6	Confident	109 Å²	109	48.2 Å²	48.2	56%	0.559	25%	0.254	S	S	*	.	H	α-helix	trans	-74	-40.1	173.8	-60.8	167.3	0	0	0	110.5	L76 I77 Q78 G82 P83 M84	L76-I80 WeakPolarHBondContact O-CG1 3.17Å; L76-I80 PolarHBondContact O-N 2.85Å; I77-I80 PolarHBondContact O-N 3.23Å; Q78-I80 VanDerWaalsContact C-N 3.32Å; I80-G82 PolarHBondContact O-N 3.38Å; I80-P83 WeakPolarHBondContact O-CD 3.3Å; I80-M84 HydrophobicContact CG2-SD 3.97Å; I80-M84 WeakPolarHBondContact O-CG 3.36Å
81	G	89.3	Confident	89.1	Confident	0 Å²	0	53.9 Å²	53.9	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-61.5	-38	-179	0	0	0	0	0	114.2	I77 Q78 M84 F85 V129 H132	I77-G81 PolarHBondContact O-N 2.97Å; Q78-G81 PolarHBondContact O-N 3.38Å; G81-M84 PolarHBondContact O-N 3.38Å; G81-F85 WeakPolarHBondContact O-CB 3.22Å; G81-F85 PolarHBondContact O-N 3.26Å; G81-V129 WeakPolarHBondContact CA-O 3.46Å; G81-H132 VanDerWaalsContact C-NE2 3.32Å
82	G	86.9	Confident	88.9	Confident	27 Å²	27	58.4 Å²	58.4	28%	0.278	30%	0.303	S	S	.	.	H	α-helix	trans	-55	-57.5	-176.2	0	0	0	0	0	113.9	Q78 I80 M84 F85 G86 H132	Q78-G82 PolarHBondContact O-N 2.97Å; I80-G82 PolarHBondContact O-N 3.38Å; G82-M84 PolarHBondContact O-N 3.15Å; G82-F85 PolarHBondContact O-N 3.17Å; G82-G86 PolarHBondContact O-N 2.99Å; G82-H132 PolarHBondContact N-NE2 3.23Å
83	P	83	Confident	88.7	Confident	53 Å²	53	58.3 Å²	58.3	34%	0.344	31%	0.306	S	S	.	.	H	α-helix	trans	-60.2	-40.6	175.3	-26.9	35.7	0	0	0	113.8	L79 I80 G86 R87 V225	L79-P83 VanDerWaalsContact O-CD 3.25Å; L79-P83 WeakPolarHBondContact O-CD 3.41Å; I80-P83 WeakPolarHBondContact O-CD 3.3Å; P83-G86 PolarHBondContact O-N 3.47Å; P83-R87 PolarHBondContact O-N 3Å; P83-R87 VanDerWaalsContact O-N 3.08Å; P83-V225 HydrophobicContact CB-CG1 3.92Å; P83-V225 HydrophobicContact CG-CG1 4.28Å
84	M	87.8	Confident	88.5	Confident	99 Å²	99	56.3 Å²	56.3	49%	0.488	29%	0.294	S	S	.	.	H	α-helix	trans	-62.6	-45	178.2	-69.2	-177.9	64.7	0	0	111.3	I80 G81 G82 F88	I80-M84 HydrophobicContact CG2-SD 3.97Å; I80-M84 WeakPolarHBondContact O-CG 3.36Å; G81-M84 PolarHBondContact O-N 3.38Å; G82-M84 PolarHBondContact O-N 3.15Å; M84-F88 WeakPolarHBondContact O-CB 3.26Å; M84-F88 PolarHBondContact O-N 2.91Å
85	F	89.3	Confident	88.5	Confident	7 Å²	7	58.3 Å²	58.3	3%	0.031	30%	0.3	C	S	.	.	H	α-helix	trans	-67.1	-43.1	178.6	-175.9	-93.1	0	0	0	112.1	G81 G82 R87 F88 G89 A97 A101 F130 H132 A136	G81-F85 WeakPolarHBondContact O-CB 3.22Å; G81-F85 PolarHBondContact O-N 3.26Å; G82-F85 PolarHBondContact O-N 3.17Å; F85-R87 PolarHBondContact O-N 3.21Å; F85-F88 WeakPolarHBondContact O-CB 3.28Å; F85-F88 PolarHBondContact O-N 3.11Å; F85-F88 VanDerWaalsContact O-N 3.17Å; F85-G89 PolarHBondContact O-N 2.73Å; F85-A97 HydrophobicContact CE1-CB 4.36Å; F85-A97 HydrophobicContact CE2-CB 4.31Å; F85-A97 WeakPolarHBondContact CE2-O 3.48Å; F85-A97 HydrophobicContact CZ-CB 3.86Å; F85-A97 WeakPolarHBondContact CZ-O 3.46Å; F85-A101 HydrophobicContact CE2-CB 3.8Å; F85-A101 HydrophobicContact CZ-CB 3.9Å; F85-F130 WeakPolarHBondContact CE2-O 3.41Å; F85-H132 HydrophobicContact CB-CB 4.35Å; F85-H132 HydrophobicContact CD1-CB 3.35Å; F85-H132 HydrophobicContact CD2-CB 4.02Å; F85-H132 HydrophobicContact CE1-CB 3.47Å; F85-H132 VanDerWaalsContact CE1-CB 3.47Å; F85-H132 VanDerWaalsContact CE1-O 3.29Å; F85-H132 WeakPolarHBondContact CE1-O 3.36Å; F85-H132 HydrophobicContact CE2-CB 4.13Å; F85-H132 HydrophobicContact CG-CB 3.63Å; F85-H132 AromaticContact CG-CD2 3.74Å; F85-H132 AromaticContact CG-CG 3.98Å; F85-H132 HydrophobicContact CZ-CB 3.85Å; F85-H132 WeakPolarHBondContact CZ-O 3.34Å; F85-A136 HydrophobicContact CE1-CB 3.97Å; F85-A136 HydrophobicContact CZ-CB 3.8Å
86	G	83.4	Confident	88.7	Confident	28 Å²	28	59.8 Å²	59.8	29%	0.289	31%	0.312	S	S	.	.	H	α-helix	trans	-56.2	-50.3	175.3	0	0	0	0	0	111.4	G82 P83 F88 G89 D90	G82-G86 PolarHBondContact O-N 2.99Å; P83-G86 PolarHBondContact O-N 3.47Å; G86-F88 VanDerWaalsContact C-N 3.32Å; G86-F88 PolarHBondContact O-N 3.47Å; G86-G89 PolarHBondContact O-N 3.07Å; G86-D90 PolarHBondContact O-N 3.45Å
87	R	83.8	Confident	88.7	Confident	178 Å²	178	55.5 Å²	55.5	67%	0.672	29%	0.29	S	S	*	.	H	α-helix	trans	-61.6	-38.8	176	-175.4	174.4	178.6	149.7	0.2	112.5	P83 F85 D90 L91	P83-R87 PolarHBondContact O-N 3Å; P83-R87 VanDerWaalsContact O-N 3.08Å; F85-R87 PolarHBondContact O-N 3.21Å; R87-D90 PolarHBondContact O-N 3.09Å; R87-L91 HydrophobicContact CG-CD1 4.01Å; R87-L91 HydrophobicContact CG-CG 4.47Å; R87-L91 VanDerWaalsContact O-CG 3.32Å; R87-L91 WeakPolarHBondContact O-CG 3.31Å; R87-L91 PolarHBondContact O-N 3.35Å; R87-L91 VanDerWaalsContact O-N 3.09Å
88	F	87.3	Confident	88.7	Confident	57 Å²	57	54.2 Å²	54.2	25%	0.25	28%	0.283	C	S	.	.	H	α-helix	trans	-60.9	-45.4	175.5	-177	-89.1	0	0	0	111.5	M84 F85 G86 D90 L91 F92 A96 A97 L100	M84-F88 WeakPolarHBondContact O-CB 3.26Å; M84-F88 PolarHBondContact O-N 2.91Å; F85-F88 WeakPolarHBondContact O-CB 3.28Å; F85-F88 PolarHBondContact O-N 3.11Å; F85-F88 VanDerWaalsContact O-N 3.17Å; G86-F88 VanDerWaalsContact C-N 3.32Å; G86-F88 PolarHBondContact O-N 3.47Å; F88-D90 VanDerWaalsContact C-N 3.33Å; F88-D90 PolarHBondContact O-N 2.92Å; F88-L91 PolarHBondContact O-N 2.96Å; F88-F92 HydrophobicContact CD1-CD2 4.34Å; F88-F92 AromaticContact CD2-CD2 3.42Å; F88-F92 HydrophobicContact CD2-CD2 3.42Å; F88-F92 VanDerWaalsContact CD2-CD2 3.42Å; F88-F92 AromaticContact CD2-CE2 3.69Å; F88-F92 HydrophobicContact CD2-CE2 3.69Å; F88-F92 HydrophobicContact CD2-CG 4.46Å; F88-F92 HydrophobicContact CE1-CB 4.23Å; F88-F92 HydrophobicContact CE1-CD2 4.31Å; F88-F92 AromaticContact CE2-CD2 3.39Å; F88-F92 HydrophobicContact CE2-CD2 3.39Å; F88-F92 AromaticContact CE2-CE2 3.67Å; F88-F92 HydrophobicContact CE2-CE2 3.67Å; F88-F92 HydrophobicContact CE2-CG 4.09Å; F88-F92 AromaticContact CG-CD2 3.92Å; F88-F92 HydrophobicContact CG-CD2 3.92Å; F88-F92 HydrophobicContact CZ-CB 4.23Å; F88-F92 AromaticContact CZ-CD2 3.86Å; F88-F92 HydrophobicContact CZ-CD2 3.86Å; F88-F92 HydrophobicContact CZ-CG 4.14Å; F88-F92 WeakPolarHBondContact O-CD2 3.48Å; F88-F92 PolarHBondContact O-N 2.65Å; F88-A96 HydrophobicContact CE1-CB 4.22Å; F88-A97 HydrophobicContact CD1-CB 4.24Å; F88-L100 HydrophobicContact CD1-CD2 3.76Å; F88-L100 HydrophobicContact CD2-CD2 4.21Å; F88-L100 HydrophobicContact CE1-CB 4.06Å; F88-L100 HydrophobicContact CE1-CD2 3.61Å; F88-L100 HydrophobicContact CE1-CG 4.48Å; F88-L100 HydrophobicContact CE2-CD2 4.07Å; F88-L100 HydrophobicContact CG-CD2 4.06Å; F88-L100 HydrophobicContact CZ-CB 4.49Å; F88-L100 HydrophobicContact CZ-CD2 3.78Å
89	G	86.4	Confident	89	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-64.6	-34.8	176.3	0	0	0	0	0	113.8	F85 G86 G93	F85-G89 PolarHBondContact O-N 2.73Å; G86-G89 PolarHBondContact O-N 3.07Å; G89-G93 CarbonylContact O-C 3.5Å; G89-G93 WeakPolarHBondContact O-CA 3.37Å; G89-G93 PolarHBondContact O-N 3.48Å
90	D	84.2	Confident	89.5	Confident	76 Å²	76	50.5 Å²	50.5	41%	0.406	27%	0.267	S	S	.	.	H	α-helix	trans	-66.8	-38.2	175.3	-71.7	-29.9	0	0	0	112.9	G86 R87 F88	G86-D90 PolarHBondContact O-N 3.45Å; R87-D90 PolarHBondContact O-N 3.09Å; F88-D90 VanDerWaalsContact C-N 3.33Å; F88-D90 PolarHBondContact O-N 2.92Å
91	L	85.7	Confident	89.9	Confident	119 Å²	119	45.3 Å²	45.3	62%	0.623	24%	0.24	S	C	*	.	H	α-helix	trans	-80.6	-44.2	-177.8	-69	173.4	0	0	0	113	R87 F88	R87-L91 HydrophobicContact CG-CD1 4.01Å; R87-L91 HydrophobicContact CG-CG 4.47Å; R87-L91 VanDerWaalsContact O-CG 3.32Å; R87-L91 WeakPolarHBondContact O-CG 3.31Å; R87-L91 PolarHBondContact O-N 3.35Å; R87-L91 VanDerWaalsContact O-N 3.09Å; F88-L91 PolarHBondContact O-N 2.96Å
92	F	87.7	Confident	90.3	Very high	132 Å²	132	45.5 Å²	45.5	58%	0.579	24%	0.241	S	C	*	.	H	α-helix	trans	-104.9	-7.5	-171.3	-62	-78.1	0	0	0	113.6	F88 A96	F88-F92 HydrophobicContact CD1-CD2 4.34Å; F88-F92 AromaticContact CD2-CD2 3.42Å; F88-F92 HydrophobicContact CD2-CD2 3.42Å; F88-F92 VanDerWaalsContact CD2-CD2 3.42Å; F88-F92 AromaticContact CD2-CE2 3.69Å; F88-F92 HydrophobicContact CD2-CE2 3.69Å; F88-F92 HydrophobicContact CD2-CG 4.46Å; F88-F92 HydrophobicContact CE1-CB 4.23Å; F88-F92 HydrophobicContact CE1-CD2 4.31Å; F88-F92 AromaticContact CE2-CD2 3.39Å; F88-F92 HydrophobicContact CE2-CD2 3.39Å; F88-F92 AromaticContact CE2-CE2 3.67Å; F88-F92 HydrophobicContact CE2-CE2 3.67Å; F88-F92 HydrophobicContact CE2-CG 4.09Å; F88-F92 AromaticContact CG-CD2 3.92Å; F88-F92 HydrophobicContact CG-CD2 3.92Å; F88-F92 HydrophobicContact CZ-CB 4.23Å; F88-F92 AromaticContact CZ-CD2 3.86Å; F88-F92 HydrophobicContact CZ-CD2 3.86Å; F88-F92 HydrophobicContact CZ-CG 4.14Å; F88-F92 WeakPolarHBondContact O-CD2 3.48Å; F88-F92 PolarHBondContact O-N 2.65Å; F92-A96 HydrophobicContact CB-CB 3.75Å; F92-A96 WeakPolarHBondContact O-CB 3.3Å
93	G	89.8	Confident	90.8	Very high	19 Å²	19	45.8 Å²	45.8	20%	0.196	24%	0.241	C	C	.	.			trans	85.9	167	177.8	0	0	0	0	0	114.4	G89 R95 A96 A97	G89-G93 CarbonylContact O-C 3.5Å; G89-G93 WeakPolarHBondContact O-CA 3.37Å; G89-G93 PolarHBondContact O-N 3.48Å; G93-R95 PolarHBondContact O-N 3.44Å; G93-A96 PolarHBondContact O-N 3.17Å; G93-A97 PolarHBondContact O-N 2.92Å; G93-A97 VanDerWaalsContact O-N 3.09Å
94	A	91.1	Very high	91.6	Very high	1 Å²	1	43.8 Å²	43.8	1%	0.008	23%	0.229	C	C	.	.	H	α-helix	trans	-63.3	-38.8	-169.8	0	0	0	0	0	113.7	A97 L98 M139 V140 T207	A94-A97 PolarHBondContact O-N 3.32Å; A94-L98 VanDerWaalsContact O-CB 3.23Å; A94-L98 WeakPolarHBondContact O-CB 3.22Å; A94-L98 PolarHBondContact O-N 3.11Å; A94-M139 HydrophobicContact CB-CB 4.39Å; A94-M139 HydrophobicContact CB-CG 3.96Å; A94-M139 HydrophobicContact CB-SD 3.64Å; A94-V140 HydrophobicContact CB-CG2 3.56Å; A94-T207 HydrophobicContact CB-CG2 4.17Å; A94-T207 WeakPolarHBondContact CB-OG1 3.29Å
95	R	94.5	Very high	92.1	Very high	55 Å²	55	39.2 Å²	39.2	21%	0.208	21%	0.206	C	C	.	.	H	α-helix	trans	-61.4	-47	176.6	-177.3	-172.3	168.6	139.9	-7.4	111.7	G93 L98 S99 V199 L200 I203 P204	G93-R95 PolarHBondContact O-N 3.44Å; R95-L98 PolarHBondContact O-N 3.46Å; R95-S99 WeakPolarHBondContact O-CB 3.21Å; R95-S99 PolarHBondContact O-N 2.97Å; R95-S99 PolarHBondContact O-OG 2.85Å; R95-S99 VanDerWaalsContact O-OG 3.09Å; R95-V199 HydrophobicContact CG-CG1 4.38Å; R95-L200 VanDerWaalsContact CZ-O 3.22Å; R95-L200 PolarHBondContact NH1-O 3.41Å; R95-L200 PolarHBondContact NH2-O 3.04Å; R95-I203 HydrophobicContact CB-CG2 3.93Å; R95-I203 VanDerWaalsContact CD-O 3.28Å; R95-I203 WeakPolarHBondContact CD-O 3.31Å; R95-I203 HydrophobicContact CG-CB 4.3Å; R95-I203 HydrophobicContact CG-CG2 4.19Å; R95-I203 PolarHBondContact NH1-O 3.06Å; R95-P204 WeakPolarHBondContact CB-O 3.32Å
96	A	94.6	Very high	92.5	Very high	35 Å²	35	39.8 Å²	39.8	29%	0.289	21%	0.211	S	C	.	.	H	α-helix	trans	-64.7	-44.6	-179.2	0	0	0	0	0	111.1	F88 F92 G93 S99 L100	F88-A96 HydrophobicContact CE1-CB 4.22Å; F92-A96 HydrophobicContact CB-CB 3.75Å; F92-A96 WeakPolarHBondContact O-CB 3.3Å; G93-A96 PolarHBondContact O-N 3.17Å; A96-S99 PolarHBondContact O-N 2.93Å; A96-L100 WeakPolarHBondContact O-CB 3.37Å; A96-L100 PolarHBondContact O-N 2.83Å
97	A	94.6	Very high	93.2	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-59.7	-46.4	175.5	0	0	0	0	0	112.2	F85 F88 G93 A94 L100 A101 A136	F85-A97 HydrophobicContact CE1-CB 4.36Å; F85-A97 HydrophobicContact CE2-CB 4.31Å; F85-A97 WeakPolarHBondContact CE2-O 3.48Å; F85-A97 HydrophobicContact CZ-CB 3.86Å; F85-A97 WeakPolarHBondContact CZ-O 3.46Å; F88-A97 HydrophobicContact CD1-CB 4.24Å; G93-A97 PolarHBondContact O-N 2.92Å; G93-A97 VanDerWaalsContact O-N 3.09Å; A94-A97 PolarHBondContact O-N 3.32Å; A97-L100 PolarHBondContact O-N 3.46Å; A97-A101 WeakPolarHBondContact O-CB 3.3Å; A97-A101 PolarHBondContact O-N 3.06Å; A97-A136 HydrophobicContact CB-CB 4.32Å
98	L	95.7	Very high	93.9	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-65.9	-40.4	179.7	-170	58.9	0	0	0	111.9	I38 A94 R95 A101 C102 V133 A136 C137 V140 V199 I203	I38-L98 HydrophobicContact CD1-CD2 4.43Å; I38-L98 HydrophobicContact CG2-CD1 4.43Å; A94-L98 VanDerWaalsContact O-CB 3.23Å; A94-L98 WeakPolarHBondContact O-CB 3.22Å; A94-L98 PolarHBondContact O-N 3.11Å; R95-L98 PolarHBondContact O-N 3.46Å; L98-A101 PolarHBondContact O-N 3.34Å; L98-C102 PolarHBondContact O-N 3.06Å; L98-C102 PolarHBondContact O-SG 3.36Å; L98-C102 VanDerWaalsContact O-SG 3.38Å; L98-V133 HydrophobicContact CD1-CB 4.48Å; L98-V133 HydrophobicContact CD1-CG1 3.74Å; L98-A136 HydrophobicContact CB-CB 3.98Å; L98-A136 HydrophobicContact CD1-CB 3.83Å; L98-A136 HydrophobicContact CG-CB 4.49Å; L98-C137 WeakPolarHBondContact CD1-SG 3.14Å; L98-V140 HydrophobicContact CD2-CG2 4.48Å; L98-V199 HydrophobicContact CB-CG1 4.05Å; L98-V199 HydrophobicContact CD2-CG1 4.05Å; L98-V199 HydrophobicContact CD2-CG2 3.69Å; L98-V199 HydrophobicContact CG-CB 4.49Å; L98-V199 HydrophobicContact CG-CG1 3.98Å; L98-V199 HydrophobicContact CG-CG2 3.6Å; L98-I203 HydrophobicContact CD2-CG1 4.22Å
99	S	97.7	Very high	94.4	Very high	18 Å²	18	30.7 Å²	30.7	13%	0.126	17%	0.173	C	C	.	.	H	α-helix	trans	-62.5	-44.2	173.4	-67.1	0	0	0	0	112.2	R95 A96 A101 C102 A103 L196 V199 L200	R95-S99 WeakPolarHBondContact O-CB 3.21Å; R95-S99 PolarHBondContact O-N 2.97Å; R95-S99 PolarHBondContact O-OG 2.85Å; R95-S99 VanDerWaalsContact O-OG 3.09Å; A96-S99 PolarHBondContact O-N 2.93Å; S99-A101 VanDerWaalsContact C-N 3.33Å; S99-A101 PolarHBondContact O-N 2.73Å; S99-C102 PolarHBondContact O-N 3.35Å; S99-A103 VanDerWaalsContact O-CB 3.25Å; S99-A103 WeakPolarHBondContact O-CB 3.37Å; S99-A103 PolarHBondContact O-N 3.5Å; S99-L196 WeakPolarHBondContact O-CD1 3.46Å; S99-V199 VanDerWaalsContact OG-CG1 3.3Å; S99-V199 WeakPolarHBondContact OG-CG1 3.31Å; S99-L200 WeakPolarHBondContact OG-CD2 3.4Å
100	L	97.4	Very high	95	Very high	48 Å²	48	35.2 Å²	35.2	25%	0.251	20%	0.197	S	C	.	.	H	α-helix	trans	-60.9	-43.9	176.6	178.7	63.1	0	0	0	111	F88 A96 A97 A103 A104 F130	F88-L100 HydrophobicContact CD1-CD2 3.76Å; F88-L100 HydrophobicContact CD2-CD2 4.21Å; F88-L100 HydrophobicContact CE1-CB 4.06Å; F88-L100 HydrophobicContact CE1-CD2 3.61Å; F88-L100 HydrophobicContact CE1-CG 4.48Å; F88-L100 HydrophobicContact CE2-CD2 4.07Å; F88-L100 HydrophobicContact CG-CD2 4.06Å; F88-L100 HydrophobicContact CZ-CB 4.49Å; F88-L100 HydrophobicContact CZ-CD2 3.78Å; A96-L100 WeakPolarHBondContact O-CB 3.37Å; A96-L100 PolarHBondContact O-N 2.83Å; A97-L100 PolarHBondContact O-N 3.46Å; L100-A103 PolarHBondContact O-N 2.93Å; L100-A104 WeakPolarHBondContact O-CB 3.3Å; L100-A104 PolarHBondContact O-N 3.43Å; L100-F130 HydrophobicContact CD1-CD2 4.46Å; L100-F130 HydrophobicContact CD1-CG 4.47Å; L100-F130 HydrophobicContact CD2-CB 4.34Å; L100-F130 HydrophobicContact CD2-CD1 3.84Å; L100-F130 HydrophobicContact CD2-CE1 4.3Å; L100-F130 HydrophobicContact CD2-CG 4.03Å; L100-F130 HydrophobicContact CG-CB 4.11Å; L100-F130 HydrophobicContact CG-CD1 4.48Å; L100-F130 HydrophobicContact CG-CG 4.19Å
101	A	97.5	Very high	95.6	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-64	-47.6	179.2	0	0	0	0	0	112.4	F85 A97 L98 S99 A103 A104 T105 F130 V133	F85-A101 HydrophobicContact CE2-CB 3.8Å; F85-A101 HydrophobicContact CZ-CB 3.9Å; A97-A101 WeakPolarHBondContact O-CB 3.3Å; A97-A101 PolarHBondContact O-N 3.06Å; L98-A101 PolarHBondContact O-N 3.34Å; S99-A101 VanDerWaalsContact C-N 3.33Å; S99-A101 PolarHBondContact O-N 2.73Å; A101-A103 PolarHBondContact O-N 3.42Å; A101-A104 PolarHBondContact O-N 2.96Å; A101-T105 PolarHBondContact O-N 2.87Å; A101-T105 PolarHBondContact O-OG1 3.08Å; A101-T105 VanDerWaalsContact O-OG1 3.13Å; A101-F130 VanDerWaalsContact CA-O 3.25Å; A101-F130 WeakPolarHBondContact CA-O 3.35Å; A101-F130 WeakPolarHBondContact CB-O 3.32Å; A101-V133 HydrophobicContact CB-CB 4.33Å; A101-V133 HydrophobicContact CB-CG2 3.51Å
102	C	97.9	Very high	96.2	Very high	3 Å²	3	28.4 Å²	28.4	2%	0.02	16%	0.161	C	C	.	.	H	α-helix	trans	-64.2	-40.4	176.9	-65.7	0	0	0	0	112	L98 S99 T105 T106 L196	L98-C102 PolarHBondContact O-N 3.06Å; L98-C102 PolarHBondContact O-SG 3.36Å; L98-C102 VanDerWaalsContact O-SG 3.38Å; S99-C102 PolarHBondContact O-N 3.35Å; C102-T105 WeakPolarHBondContact O-CB 3.5Å; C102-T105 PolarHBondContact O-N 3.29Å; C102-T106 PolarHBondContact O-N 3.35Å; C102-T106 PolarHBondContact O-OG1 2.94Å; C102-L196 HydrophobicContact CB-CB 3.83Å; C102-L196 HydrophobicContact CB-CD1 4.21Å
103	A	98.4	Very high	96.6	Very high	34 Å²	34	22.7 Å²	22.7	28%	0.281	14%	0.138	S	C	.	.	H	α-helix	trans	-62.4	-42.3	175.8	0	0	0	0	0	111.8	S99 L100 A101 T105 T106 V107 L196	S99-A103 VanDerWaalsContact O-CB 3.25Å; S99-A103 WeakPolarHBondContact O-CB 3.37Å; S99-A103 PolarHBondContact O-N 3.5Å; L100-A103 PolarHBondContact O-N 2.93Å; A101-A103 PolarHBondContact O-N 3.42Å; A103-T105 VanDerWaalsContact C-N 3.34Å; A103-T105 PolarHBondContact O-N 3.11Å; A103-T106 WeakPolarHBondContact O-CB 3.47Å; A103-T106 PolarHBondContact O-N 3.47Å; A103-V107 WeakPolarHBondContact O-CG2 3.44Å; A103-V107 PolarHBondContact O-N 2.91Å; A103-L196 HydrophobicContact CB-CD2 4.05Å
104	A	98.3	Very high	97	Very high	10 Å²	10	26.1 Å²	26.1	8%	0.083	16%	0.155	C	C	.	.	H	α-helix	trans	-61.9	-41.1	175.3	0	0	0	0	0	111.9	L100 A101 V107 S108 P127 F130 M131	L100-A104 WeakPolarHBondContact O-CB 3.3Å; L100-A104 PolarHBondContact O-N 3.43Å; A101-A104 PolarHBondContact O-N 2.96Å; A104-V107 PolarHBondContact O-N 2.87Å; A104-S108 WeakPolarHBondContact O-CB 3.42Å; A104-S108 PolarHBondContact O-N 2.94Å; A104-P127 HydrophobicContact CB-CB 4.26Å; A104-P127 VanDerWaalsContact O-CB 3.3Å; A104-P127 WeakPolarHBondContact O-CB 3.47Å; A104-F130 HydrophobicContact CB-CB 3.84Å; A104-M131 HydrophobicContact CB-CG 3.98Å
105	T	98.1	Very high	97.2	Very high	4 Å²	4	26.4 Å²	26.4	3%	0.025	16%	0.157	C	C	.	.	H	α-helix	trans	-60	-44.8	172.7	-58	0	0	0	0	111.4	A101 C102 A103 S108 F109 M131	A101-T105 PolarHBondContact O-N 2.87Å; A101-T105 PolarHBondContact O-OG1 3.08Å; A101-T105 VanDerWaalsContact O-OG1 3.13Å; C102-T105 WeakPolarHBondContact O-CB 3.5Å; C102-T105 PolarHBondContact O-N 3.29Å; A103-T105 VanDerWaalsContact C-N 3.34Å; A103-T105 PolarHBondContact O-N 3.11Å; T105-S108 WeakPolarHBondContact O-CB 3.25Å; T105-S108 PolarHBondContact O-N 3.25Å; T105-F109 HydrophobicContact CG2-CD2 3.9Å; T105-F109 HydrophobicContact CG2-CE2 3.78Å; T105-F109 VanDerWaalsContact O-CD2 3.31Å; T105-F109 WeakPolarHBondContact O-CD2 3.21Å; T105-F109 PolarHBondContact O-N 3.1Å; T105-M131 HydrophobicContact CG2-CE 4.01Å
106	T	98.6	Very high	97.1	Very high	19 Å²	19	29.8 Å²	29.8	12%	0.117	18%	0.179	C	C	.	.	H	α-helix	trans	-60.6	-47	176	-58.7	0	0	0	0	112.3	C102 A103 S108 F109 L110 S192 A193	C102-T106 PolarHBondContact O-N 3.35Å; C102-T106 PolarHBondContact O-OG1 2.94Å; A103-T106 WeakPolarHBondContact O-CB 3.47Å; A103-T106 PolarHBondContact O-N 3.47Å; T106-S108 VanDerWaalsContact C-N 3.33Å; T106-S108 PolarHBondContact O-N 3.1Å; T106-F109 PolarHBondContact O-N 3.32Å; T106-L110 HydrophobicContact CG2-CD1 4.11Å; T106-L110 HydrophobicContact CG2-CG 4.41Å; T106-L110 WeakPolarHBondContact O-CG 3.46Å; T106-L110 PolarHBondContact O-N 3.1Å; T106-S192 WeakPolarHBondContact CA-OG 3.41Å; T106-S192 PolarHBondContact N-OG 3.15Å; T106-S192 VanDerWaalsContact OG1-C 3.26Å; T106-S192 WeakPolarHBondContact OG1-CB 3.46Å; T106-S192 PolarHBondContact OG1-OG 3.5Å; T106-A193 HydrophobicContact CG2-CB 4.06Å; T106-A193 PolarHBondContact OG1-N 2.92Å; T106-A193 VanDerWaalsContact OG1-N 3.13Å
107	V	98.5	Very high	97.1	Very high	70 Å²	70	32.9 Å²	32.9	42%	0.424	19%	0.188	S	C	.	.	H	α-helix	trans	-61.8	-42	177.6	174.7	0	0	0	0	111.1	A103 A104 F109 L110 L111 P127	A103-V107 WeakPolarHBondContact O-CG2 3.44Å; A103-V107 PolarHBondContact O-N 2.91Å; A104-V107 PolarHBondContact O-N 2.87Å; V107-F109 VanDerWaalsContact C-N 3.33Å; V107-F109 PolarHBondContact O-N 2.89Å; V107-L110 PolarHBondContact O-N 2.83Å; V107-L111 HydrophobicContact CG1-CD1 3.92Å; V107-L111 HydrophobicContact CG1-CG 4.34Å; V107-L111 WeakPolarHBondContact O-CB 3.43Å; V107-L111 VanDerWaalsContact O-CG 3.31Å; V107-L111 WeakPolarHBondContact O-CG 3.4Å; V107-L111 PolarHBondContact O-N 3.35Å; V107-P127 HydrophobicContact CB-CG 4.32Å; V107-P127 HydrophobicContact CG1-CG 3.83Å
108	S	98.1	Very high	97	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-56.8	-44.2	174.4	166.1	0	0	0	0	111.9	A104 T105 T106 L112 H124	A104-S108 WeakPolarHBondContact O-CB 3.42Å; A104-S108 PolarHBondContact O-N 2.94Å; T105-S108 WeakPolarHBondContact O-CB 3.25Å; T105-S108 PolarHBondContact O-N 3.25Å; T106-S108 VanDerWaalsContact C-N 3.33Å; T106-S108 PolarHBondContact O-N 3.1Å; S108-L112 WeakPolarHBondContact O-CB 3.46Å; S108-L112 PolarHBondContact O-N 3.42Å; S108-H124 WeakPolarHBondContact CB-O 3.13Å; S108-H124 PolarHBondContact OG-O 3.05Å
109	F	98.1	Very high	96.9	Very high	1 Å²	1	38.9 Å²	38.9	0%	0.004	23%	0.225	C	C	.	.	H	α-helix	trans	-70.7	-38.2	177.2	-84.9	-68.4	0	0	0	114	W45 L48 Q49 T105 T106 V107 L111 L112 A113 A189	W45-F109 HydrophobicContact CB-CE2 3.76Å; W45-F109 HydrophobicContact CB-CZ 4.02Å; W45-F109 WeakPolarHBondContact O-CZ 3.32Å; L48-F109 HydrophobicContact CD2-CE1 3.74Å; L48-F109 HydrophobicContact CD2-CZ 4.21Å; Q49-F109 HydrophobicContact CB-CE1 3.98Å; Q49-F109 HydrophobicContact CB-CZ 3.82Å; Q49-F109 HydrophobicContact CG-CE1 4.38Å; Q49-F109 HydrophobicContact CG-CZ 4.48Å; T105-F109 HydrophobicContact CG2-CD2 3.9Å; T105-F109 HydrophobicContact CG2-CE2 3.78Å; T105-F109 VanDerWaalsContact O-CD2 3.31Å; T105-F109 WeakPolarHBondContact O-CD2 3.21Å; T105-F109 PolarHBondContact O-N 3.1Å; T106-F109 PolarHBondContact O-N 3.32Å; V107-F109 VanDerWaalsContact C-N 3.33Å; V107-F109 PolarHBondContact O-N 2.89Å; F109-L111 VanDerWaalsContact C-N 3.33Å; F109-L112 HydrophobicContact CD1-CD2 4.21Å; F109-L112 HydrophobicContact CE1-CD2 4.39Å; F109-L112 WeakPolarHBondContact O-CB 3.42Å; F109-L112 PolarHBondContact O-N 3.2Å; F109-A113 WeakPolarHBondContact O-CB 3.29Å; F109-A113 PolarHBondContact O-N 3.38Å; F109-A189 HydrophobicContact CB-CB 3.72Å
110	L	98.3	Very high	96.8	Very high	96 Å²	96	40.4 Å²	40.4	50%	0.503	23%	0.232	S	C	.	.	H	α-helix	trans	-62	-43.8	175.3	-71.7	173.3	0	0	0	111	T106 V107 L112 A113 V114 A189	T106-L110 HydrophobicContact CG2-CD1 4.11Å; T106-L110 HydrophobicContact CG2-CG 4.41Å; T106-L110 WeakPolarHBondContact O-CG 3.46Å; T106-L110 PolarHBondContact O-N 3.1Å; V107-L110 PolarHBondContact O-N 2.83Å; L110-L112 VanDerWaalsContact C-N 3.33Å; L110-L112 PolarHBondContact O-N 2.77Å; L110-A113 PolarHBondContact O-N 2.97Å; L110-V114 PolarHBondContact O-N 3.21Å; L110-A189 HydrophobicContact CD2-CB 3.76Å; L110-A189 HydrophobicContact CG-CB 4Å
111	L	97.9	Very high	96.8	Very high	52 Å²	52	38.1 Å²	38.1	27%	0.272	22%	0.22	S	C	.	.	H	α-helix	trans	-63.7	-38.6	174.6	-70.6	171.8	0	0	0	111.9	V107 F109 V114 A115 V123 H124 P127	V107-L111 HydrophobicContact CG1-CD1 3.92Å; V107-L111 HydrophobicContact CG1-CG 4.34Å; V107-L111 WeakPolarHBondContact O-CB 3.43Å; V107-L111 VanDerWaalsContact O-CG 3.31Å; V107-L111 WeakPolarHBondContact O-CG 3.4Å; V107-L111 PolarHBondContact O-N 3.35Å; F109-L111 VanDerWaalsContact C-N 3.33Å; L111-V114 WeakPolarHBondContact O-CG2 3.49Å; L111-V114 PolarHBondContact O-N 3.4Å; L111-A115 PolarHBondContact O-N 3.44Å; L111-V123 HydrophobicContact CD1-CG1 4.4Å; L111-V123 HydrophobicContact CD2-CG1 4.49Å; L111-H124 HydrophobicContact CB-CB 3.48Å; L111-H124 VanDerWaalsContact CB-CB 3.48Å; L111-P127 HydrophobicContact CD1-CG 3.97Å
112	L	97.2	Very high	96.7	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-64.9	-39.6	174.4	-178.8	64.5	0	0	0	112	Q49 L56 S108 F109 L110 V114 A115 L121 H124 A185	Q49-L112 HydrophobicContact CG-CD2 4.35Å; L56-L112 HydrophobicContact CD2-CD1 3.65Å; L56-L112 HydrophobicContact CD2-CG 4.33Å; S108-L112 WeakPolarHBondContact O-CB 3.46Å; S108-L112 PolarHBondContact O-N 3.42Å; F109-L112 HydrophobicContact CD1-CD2 4.21Å; F109-L112 HydrophobicContact CE1-CD2 4.39Å; F109-L112 WeakPolarHBondContact O-CB 3.42Å; F109-L112 PolarHBondContact O-N 3.2Å; L110-L112 VanDerWaalsContact C-N 3.33Å; L110-L112 PolarHBondContact O-N 2.77Å; L112-V114 VanDerWaalsContact C-N 3.29Å; L112-V114 PolarHBondContact O-N 3.47Å; L112-A115 VanDerWaalsContact O-CB 3.25Å; L112-A115 WeakPolarHBondContact O-CB 3.39Å; L112-A115 PolarHBondContact O-N 3.08Å; L112-A115 VanDerWaalsContact O-N 3.16Å; L112-L121 HydrophobicContact CD1-CD2 4.37Å; L112-H124 HydrophobicContact CB-CB 4.35Å; L112-A185 HydrophobicContact CB-CB 4.21Å; L112-A185 HydrophobicContact CD2-CB 3.97Å; L112-A185 HydrophobicContact CG-CB 3.86Å
113	A	96.6	Very high	96.7	Very high	12 Å²	12	43 Å²	43	10%	0.099	25%	0.245	C	C	.	.	H	α-helix	trans	-64.2	-34.6	-179.8	0	0	0	0	0	112.5	F109 L110 T182 A185	F109-A113 WeakPolarHBondContact O-CB 3.29Å; F109-A113 PolarHBondContact O-N 3.38Å; L110-A113 PolarHBondContact O-N 2.97Å; A113-T182 WeakPolarHBondContact O-CG2 3.15Å; A113-A185 HydrophobicContact CB-CB 3.86Å
114	V	96.9	Very high	96.6	Very high	91 Å²	91	41.4 Å²	41.4	55%	0.552	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	-91.1	3.5	176.8	-56.6	0	0	0	0	113.4	L110 L111 L112 N116 L120	L110-V114 PolarHBondContact O-N 3.21Å; L111-V114 WeakPolarHBondContact O-CG2 3.49Å; L111-V114 PolarHBondContact O-N 3.4Å; L112-V114 VanDerWaalsContact C-N 3.29Å; L112-V114 PolarHBondContact O-N 3.47Å; V114-N116 PolarHBondContact O-N 3.48Å; V114-L120 HydrophobicContact CG2-CD2 4.25Å
115	A	95.5	Very high	96.5	Very high	6 Å²	6	41.1 Å²	41.1	5%	0.05	23%	0.229	C	C	.	.			trans	-69.2	100.4	-177.7	0	0	0	0	0	111.1	L56 L111 L112 L120 L121	L56-A115 HydrophobicContact CD2-CB 4.39Å; L111-A115 PolarHBondContact O-N 3.44Å; L112-A115 VanDerWaalsContact O-CB 3.25Å; L112-A115 WeakPolarHBondContact O-CB 3.39Å; L112-A115 PolarHBondContact O-N 3.08Å; L112-A115 VanDerWaalsContact O-N 3.16Å; A115-L120 HydrophobicContact CB-CB 3.89Å; A115-L121 HydrophobicContact CB-CD2 4.34Å
116	N	94.1	Very high	96.5	Very high	126 Å²	126	45.8 Å²	45.8	67%	0.674	25%	0.253	S	S	*	.			trans	-111.5	-0.1	177.8	64.7	-13.9	0	0	0	113.2	L60 V114	L60-N116 WeakPolarHBondContact CD2-O 3.35Å; V114-N116 PolarHBondContact O-N 3.48Å
117	H	93	Very high	96.4	Very high	101 Å²	101	45.8 Å²	45.8	47%	0.468	25%	0.253	S	S	.	.	S	Bend	trans	-141.4	143.5	-178.7	-172.6	-92.3	0	0	0	110.6	V119 L120	H117-V119 PolarHBondContact ND1-N 3.17Å; H117-V119 PolarHBondContact O-N 3.19Å; H117-L120 HydrophobicContact CB-CD1 3.85Å; H117-L120 WeakPolarHBondContact O-CB 3.35Å; H117-L120 PolarHBondContact O-N 3.09Å
118	P	92.9	Very high	96.3	Very high	42 Å²	42	42.6 Å²	42.6	27%	0.273	23%	0.234	S	C	.	.	H	α-helix	trans	-30.4	-51.6	169.6	-45.2	43.5	0	0	0	116.9	L60 F62 L120 L121	L60-P118 WeakPolarHBondContact O-CG 3.34Å; F62-P118 HydrophobicContact CE1-CB 3.7Å; F62-P118 HydrophobicContact CE1-CG 4.24Å; P118-L120 VanDerWaalsContact C-N 3.3Å; P118-L120 PolarHBondContact O-N 3.46Å; P118-L121 VanDerWaalsContact O-CB 3.24Å; P118-L121 WeakPolarHBondContact O-CB 3.47Å; P118-L121 PolarHBondContact O-N 2.92Å
119	V	94.6	Very high	96.2	Very high	84 Å²	84	44 Å²	44	51%	0.509	24%	0.242	S	C	.	.	H	α-helix	trans	-64.1	-34.8	-176.8	175.4	0	0	0	0	112	H117 L121 F122 V123	H117-V119 PolarHBondContact ND1-N 3.17Å; H117-V119 PolarHBondContact O-N 3.19Å; V119-L121 PolarHBondContact O-N 3.38Å; V119-F122 PolarHBondContact O-N 3.34Å; V119-V123 HydrophobicContact CG1-CG2 4.25Å; V119-V123 WeakPolarHBondContact O-CG2 3.26Å; V119-V123 PolarHBondContact O-N 3.31Å
120	L	95.6	Very high	96.1	Very high	50 Å²	50	47 Å²	47	26%	0.262	26%	0.256	S	S	.	.	H	α-helix	trans	-64.9	-22.5	177.1	-81.9	87.2	0	0	0	112.1	V114 A115 H117 P118 F122 V123 H124	V114-L120 HydrophobicContact CG2-CD2 4.25Å; A115-L120 HydrophobicContact CB-CB 3.89Å; H117-L120 HydrophobicContact CB-CD1 3.85Å; H117-L120 WeakPolarHBondContact O-CB 3.35Å; H117-L120 PolarHBondContact O-N 3.09Å; P118-L120 VanDerWaalsContact C-N 3.3Å; P118-L120 PolarHBondContact O-N 3.46Å; L120-F122 VanDerWaalsContact C-N 3.34Å; L120-V123 PolarHBondContact O-N 3.45Å; L120-H124 PolarHBondContact O-N 2.9Å
121	L	95.9	Very high	96	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-62.2	-42	171.6	-63.2	171	0	0	0	111.8	L56 A57 L60 F62 L70 L112 A115 P118 V119 H124 K125	L56-L121 HydrophobicContact CD2-CD2 4.41Å; L56-L121 HydrophobicContact CG-CD2 4.45Å; A57-L121 HydrophobicContact CB-CD1 3.8Å; L60-L121 HydrophobicContact CB-CD1 4.22Å; L60-L121 HydrophobicContact CD1-CD1 3.88Å; L60-L121 HydrophobicContact CD1-CD2 4Å; L60-L121 HydrophobicContact CD1-CG 3.89Å; F62-L121 HydrophobicContact CD1-CD1 4.09Å; F62-L121 HydrophobicContact CD2-CD1 4.13Å; F62-L121 HydrophobicContact CE1-CD1 3.75Å; F62-L121 HydrophobicContact CE2-CB 4.23Å; F62-L121 HydrophobicContact CE2-CD1 3.79Å; F62-L121 HydrophobicContact CG-CD1 4.27Å; F62-L121 HydrophobicContact CZ-CB 3.98Å; F62-L121 HydrophobicContact CZ-CD1 3.59Å; F62-L121 HydrophobicContact CZ-CG 4.41Å; L70-L121 HydrophobicContact CD1-CB 4.23Å; L70-L121 WeakPolarHBondContact CD1-O 3.21Å; L70-L121 HydrophobicContact CD2-CB 4.11Å; L112-L121 HydrophobicContact CD1-CD2 4.37Å; A115-L121 HydrophobicContact CB-CD2 4.34Å; P118-L121 VanDerWaalsContact O-CB 3.24Å; P118-L121 WeakPolarHBondContact O-CB 3.47Å; P118-L121 PolarHBondContact O-N 2.92Å; V119-L121 PolarHBondContact O-N 3.38Å; L121-H124 VanDerWaalsContact CA-CD2 3.5Å; L121-H124 WeakPolarHBondContact CA-CD2 3.37Å; L121-H124 PolarHBondContact O-CD2 2.9Å; L121-H124 PolarHBondContact O-NE2 2.9Å; L121-K125 WeakPolarHBondContact O-CG 3.4Å
122	F	97.1	Very high	95.8	Very high	49 Å²	49	42.9 Å²	42.9	22%	0.215	23%	0.233	C	C	.	.	H	α-helix	trans	-72	-40.4	174.4	-70.8	-88.3	0	0	0	112	F62 W66 L70 T73 V119 L120 H124 K125	F62-F122 AromaticContact CE2-CE2 3.95Å; F62-F122 HydrophobicContact CE2-CE2 3.95Å; F62-F122 HydrophobicContact CE2-CZ 4.39Å; F62-F122 HydrophobicContact CZ-CD2 4.08Å; F62-F122 AromaticContact CZ-CE2 3.51Å; F62-F122 HydrophobicContact CZ-CE2 3.51Å; F62-F122 HydrophobicContact CZ-CZ 4.36Å; W66-F122 HydrophobicContact CE3-CE2 4.43Å; W66-F122 HydrophobicContact CE3-CZ 4.25Å; W66-F122 HydrophobicContact CZ3-CZ 4.47Å; L70-F122 HydrophobicContact CB-CE1 4.19Å; L70-F122 HydrophobicContact CB-CZ 4.22Å; L70-F122 HydrophobicContact CD1-CB 4.47Å; L70-F122 HydrophobicContact CD1-CD1 3.79Å; L70-F122 HydrophobicContact CD1-CD2 4.3Å; L70-F122 HydrophobicContact CD1-CE1 4.04Å; L70-F122 HydrophobicContact CD1-CG 3.93Å; L70-F122 HydrophobicContact CD1-CZ 4.39Å; T73-F122 HydrophobicContact CG2-CD1 4.23Å; V119-F122 PolarHBondContact O-N 3.34Å; L120-F122 VanDerWaalsContact C-N 3.34Å; F122-H124 PolarHBondContact O-N 3Å; F122-K125 WeakPolarHBondContact O-CB 3.15Å; F122-K125 PolarHBondContact O-N 3.42Å; F122-K125 VanDerWaalsContact O-N 3.08Å
123	V	97.3	Very high	95.7	Very high	56 Å²	56	43 Å²	43	34%	0.339	23%	0.233	S	C	.	.	H	α-helix	trans	-61.8	-42	-179.3	176.1	0	0	0	0	111.7	L111 V119 L120 K125 L126	L111-V123 HydrophobicContact CD1-CG1 4.4Å; L111-V123 HydrophobicContact CD2-CG1 4.49Å; V119-V123 HydrophobicContact CG1-CG2 4.25Å; V119-V123 WeakPolarHBondContact O-CG2 3.26Å; V119-V123 PolarHBondContact O-N 3.31Å; L120-V123 PolarHBondContact O-N 3.45Å; V123-K125 PolarHBondContact O-N 3.26Å; V123-K125 VanDerWaalsContact O-N 3.1Å; V123-L126 HydrophobicContact CG1-CD1 4.39Å; V123-L126 WeakPolarHBondContact O-CB 3.39Å; V123-L126 WeakPolarHBondContact O-CG 3.16Å; V123-L126 PolarHBondContact O-N 2.91Å
124	H	96.3	Very high	95.6	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-14	179	91.3	77.4	0	0	0	113.3	Q49 S108 L111 L112 L120 L121 F122 P127	Q49-H124 PolarHBondContact NE2-CE1 3.14Å; S108-H124 WeakPolarHBondContact CB-O 3.13Å; S108-H124 PolarHBondContact OG-O 3.05Å; L111-H124 HydrophobicContact CB-CB 3.48Å; L111-H124 VanDerWaalsContact CB-CB 3.48Å; L112-H124 HydrophobicContact CB-CB 4.35Å; L120-H124 PolarHBondContact O-N 2.9Å; L121-H124 VanDerWaalsContact CA-CD2 3.5Å; L121-H124 WeakPolarHBondContact CA-CD2 3.37Å; L121-H124 PolarHBondContact O-CD2 2.9Å; L121-H124 PolarHBondContact O-NE2 2.9Å; F122-H124 PolarHBondContact O-N 3Å; H124-P127 WeakPolarHBondContact O-CD 3.23Å
125	K	96.1	Very high	95.3	Very high	4 Å²	4	43.2 Å²	43.2	2%	0.017	23%	0.233	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.7	-15.4	174.5	-61.2	-58	-168.8	174.1	0	113.2	L70 V74 L121 F122 V123 P127 T128	L70-K125 HydrophobicContact CD1-CG 3.86Å; V74-K125 HydrophobicContact CG2-CB 3.95Å; V74-K125 HydrophobicContact CG2-CD 3.35Å; V74-K125 HydrophobicContact CG2-CG 3.55Å; L121-K125 WeakPolarHBondContact O-CG 3.4Å; F122-K125 WeakPolarHBondContact O-CB 3.15Å; F122-K125 PolarHBondContact O-N 3.42Å; F122-K125 VanDerWaalsContact O-N 3.08Å; V123-K125 PolarHBondContact O-N 3.26Å; V123-K125 VanDerWaalsContact O-N 3.1Å; K125-P127 VanDerWaalsContact C-CD 3.48Å; K125-T128 HydrophobicContact CB-CG2 4.46Å; K125-T128 HydrophobicContact CD-CG2 4.34Å; K125-T128 WeakPolarHBondContact O-CB 3.13Å; K125-T128 WeakPolarHBondContact O-CG2 3.28Å; K125-T128 PolarHBondContact O-N 2.95Å; K125-T128 PolarHBondContact O-OG1 2.96Å
126	L	97.1	Very high	95.2	Very high	102 Å²	102	42.9 Å²	42.9	53%	0.534	23%	0.23	S	C	.	.	G	3₁₀ helix	trans	-56.2	-41.7	178.3	-62	177.6	0	0	0	113.7	I77 V123 T128 V129	I77-L126 HydrophobicContact CD1-CD2 4.06Å; V123-L126 HydrophobicContact CG1-CD1 4.39Å; V123-L126 WeakPolarHBondContact O-CB 3.39Å; V123-L126 WeakPolarHBondContact O-CG 3.16Å; V123-L126 PolarHBondContact O-N 2.91Å; L126-T128 PolarHBondContact O-N 3.28Å; L126-V129 WeakPolarHBondContact O-CG1 3.3Å; L126-V129 PolarHBondContact O-N 3.41Å
127	P	97.5	Very high	95.2	Very high	19 Å²	19	36.9 Å²	36.9	12%	0.123	20%	0.198	C	C	.	.	G	3₁₀ helix	trans	-61.8	-16.1	176	-22.6	34.5	0	0	0	114.2	A104 V107 L111 H124 K125 V129 F130	A104-P127 HydrophobicContact CB-CB 4.26Å; A104-P127 VanDerWaalsContact O-CB 3.3Å; A104-P127 WeakPolarHBondContact O-CB 3.47Å; V107-P127 HydrophobicContact CB-CG 4.32Å; V107-P127 HydrophobicContact CG1-CG 3.83Å; L111-P127 HydrophobicContact CD1-CG 3.97Å; H124-P127 WeakPolarHBondContact O-CD 3.23Å; K125-P127 VanDerWaalsContact C-CD 3.48Å; P127-V129 PolarHBondContact O-N 2.88Å; P127-F130 PolarHBondContact O-N 3.34Å
128	T	96.1	Very high	95.1	Very high	3 Å²	3	36 Å²	36	2%	0.018	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	-60.7	-17	179.4	67.6	0	0	0	0	113.5	V74 I77 K125 L126 F130 M131	V74-T128 HydrophobicContact CG1-CG2 4.19Å; I77-T128 WeakPolarHBondContact CG2-OG1 3.41Å; K125-T128 HydrophobicContact CB-CG2 4.46Å; K125-T128 HydrophobicContact CD-CG2 4.34Å; K125-T128 WeakPolarHBondContact O-CB 3.13Å; K125-T128 WeakPolarHBondContact O-CG2 3.28Å; K125-T128 PolarHBondContact O-N 2.95Å; K125-T128 PolarHBondContact O-OG1 2.96Å; L126-T128 PolarHBondContact O-N 3.28Å; T128-F130 PolarHBondContact O-N 3.44Å; T128-F130 VanDerWaalsContact O-N 3.15Å; T128-M131 HydrophobicContact CG2-CE 4.48Å; T128-M131 HydrophobicContact CG2-SD 3.57Å; T128-M131 VanDerWaalsContact CG2-SD 3.57Å; T128-M131 PolarHBondContact O-N 3Å; T128-M131 VanDerWaalsContact O-N 3.14Å
129	V	96.1	Very high	95	Very high	29 Å²	29	35.8 Å²	35.8	18%	0.176	19%	0.19	C	C	.	.	G	3₁₀ helix	trans	-55.6	-27.7	171.9	70.7	0	0	0	0	112.9	I77 G81 L126 P127	I77-V129 HydrophobicContact CG2-CB 3.62Å; I77-V129 HydrophobicContact CG2-CG2 4.37Å; I77-V129 VanDerWaalsContact CG2-N 3.33Å; G81-V129 WeakPolarHBondContact CA-O 3.46Å; L126-V129 WeakPolarHBondContact O-CG1 3.3Å; L126-V129 PolarHBondContact O-N 3.41Å; P127-V129 PolarHBondContact O-N 2.88Å
130	F	96.3	Very high	94.9	Very high	65 Å²	65	31.8 Å²	31.8	29%	0.285	17%	0.166	S	C	.	.	G	3₁₀ helix	trans	-113.7	0.1	178.3	-60.5	-57.6	0	0	0	113.5	F85 L100 A101 A104 P127 T128 H132	F85-F130 WeakPolarHBondContact CE2-O 3.41Å; L100-F130 HydrophobicContact CD1-CD2 4.46Å; L100-F130 HydrophobicContact CD1-CG 4.47Å; L100-F130 HydrophobicContact CD2-CB 4.34Å; L100-F130 HydrophobicContact CD2-CD1 3.84Å; L100-F130 HydrophobicContact CD2-CE1 4.3Å; L100-F130 HydrophobicContact CD2-CG 4.03Å; L100-F130 HydrophobicContact CG-CB 4.11Å; L100-F130 HydrophobicContact CG-CD1 4.48Å; L100-F130 HydrophobicContact CG-CG 4.19Å; A101-F130 VanDerWaalsContact CA-O 3.25Å; A101-F130 WeakPolarHBondContact CA-O 3.35Å; A101-F130 WeakPolarHBondContact CB-O 3.32Å; A104-F130 HydrophobicContact CB-CB 3.84Å; P127-F130 PolarHBondContact O-N 3.34Å; T128-F130 PolarHBondContact O-N 3.44Å; T128-F130 VanDerWaalsContact O-N 3.15Å; F130-H132 PolarHBondContact O-N 3.15Å
131	M	95.6	Very high	94.8	Very high	36 Å²	36	29.4 Å²	29.4	18%	0.177	15%	0.153	C	C	.	.			trans	-77.7	64	-177.1	-69.5	175.1	59.3	0	0	112.1	A104 T105 T128	A104-M131 HydrophobicContact CB-CG 3.98Å; T105-M131 HydrophobicContact CG2-CE 4.01Å; T128-M131 HydrophobicContact CG2-CE 4.48Å; T128-M131 HydrophobicContact CG2-SD 3.57Å; T128-M131 VanDerWaalsContact CG2-SD 3.57Å; T128-M131 PolarHBondContact O-N 3Å; T128-M131 VanDerWaalsContact O-N 3.14Å
132	H	94.4	Very high	94.4	Very high	25 Å²	25	31.4 Å²	31.4	12%	0.116	17%	0.165	C	C	.	.			trans	-118	49.7	-178.7	-66	-72.5	0	0	0	111.3	G81 G82 F85 F130 P135 A136	G81-H132 VanDerWaalsContact C-NE2 3.32Å; G82-H132 PolarHBondContact N-NE2 3.23Å; F85-H132 HydrophobicContact CB-CB 4.35Å; F85-H132 HydrophobicContact CD1-CB 3.35Å; F85-H132 HydrophobicContact CD2-CB 4.02Å; F85-H132 HydrophobicContact CE1-CB 3.47Å; F85-H132 VanDerWaalsContact CE1-CB 3.47Å; F85-H132 VanDerWaalsContact CE1-O 3.29Å; F85-H132 WeakPolarHBondContact CE1-O 3.36Å; F85-H132 HydrophobicContact CE2-CB 4.13Å; F85-H132 HydrophobicContact CG-CB 3.63Å; F85-H132 AromaticContact CG-CD2 3.74Å; F85-H132 AromaticContact CG-CG 3.98Å; F85-H132 HydrophobicContact CZ-CB 3.85Å; F85-H132 WeakPolarHBondContact CZ-O 3.34Å; F130-H132 PolarHBondContact O-N 3.15Å; H132-P135 HydrophobicContact CB-CG 4.2Å; H132-P135 WeakPolarHBondContact O-CD 3.2Å; H132-A136 PolarHBondContact O-N 3.11Å
133	V	95.6	Very high	94.1	Very high	2 Å²	2	31 Å²	31	1%	0.012	17%	0.166	C	C	.	.	H	α-helix	trans	-60.5	-47.5	-177.5	176.3	0	0	0	0	111.6	I38 D42 L98 A101 A136 C137	I38-V133 HydrophobicContact CG2-CG1 4.2Å; D42-V133 HydrophobicContact CB-CB 4.2Å; D42-V133 HydrophobicContact CB-CG1 3.71Å; D42-V133 VanDerWaalsContact CG-CB 3.44Å; D42-V133 WeakPolarHBondContact OD1-CB 3.49Å; D42-V133 VanDerWaalsContact OD1-CG2 3.29Å; D42-V133 WeakPolarHBondContact OD1-CG2 3.44Å; D42-V133 WeakPolarHBondContact OD2-CB 3.49Å; L98-V133 HydrophobicContact CD1-CB 4.48Å; L98-V133 HydrophobicContact CD1-CG1 3.74Å; A101-V133 HydrophobicContact CB-CB 4.33Å; A101-V133 HydrophobicContact CB-CG2 3.51Å; V133-A136 PolarHBondContact O-N 3.28Å; V133-A136 VanDerWaalsContact O-N 3.13Å; V133-C137 PolarHBondContact O-N 2.65Å; V133-C137 PolarHBondContact O-SG 3.3Å; V133-C137 VanDerWaalsContact O-SG 3.35Å
134	L	92.6	Very high	93.7	Very high	50 Å²	50	29.7 Å²	29.7	26%	0.262	16%	0.156	S	C	.	.	H	α-helix	trans	-58.4	-49.4	-179.6	178.6	66.9	0	0	0	113.1	V39 A136 C137 Q138 L157	V39-L134 HydrophobicContact CG1-CD1 3.9Å; V39-L134 HydrophobicContact CG2-CD1 4.39Å; L134-A136 VanDerWaalsContact C-N 3.34Å; L134-A136 PolarHBondContact O-N 3.37Å; L134-C137 WeakPolarHBondContact O-CB 3.33Å; L134-C137 PolarHBondContact O-N 2.92Å; L134-Q138 WeakPolarHBondContact O-CG 3.33Å; L134-Q138 PolarHBondContact O-N 3.23Å; L134-L157 HydrophobicContact CD1-CD1 4.45Å
135	P	91.1	Very high	93.4	Very high	58 Å²	58	30.4 Å²	30.4	38%	0.377	16%	0.161	S	C	.	.	H	α-helix	trans	-55.5	-41.5	170.9	-29.5	34.7	0	0	0	114.7	H132 Q138 M139	H132-P135 HydrophobicContact CB-CG 4.2Å; H132-P135 WeakPolarHBondContact O-CD 3.2Å; P135-Q138 WeakPolarHBondContact O-CB 3.43Å; P135-Q138 PolarHBondContact O-N 3.03Å; P135-M139 PolarHBondContact O-N 3.06Å
136	A	93.1	Very high	93.1	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-66.8	-38.1	176.9	0	0	0	0	0	112.4	F85 A97 L98 H132 V133 L134 M139 V140	F85-A136 HydrophobicContact CE1-CB 3.97Å; F85-A136 HydrophobicContact CZ-CB 3.8Å; A97-A136 HydrophobicContact CB-CB 4.32Å; L98-A136 HydrophobicContact CB-CB 3.98Å; L98-A136 HydrophobicContact CD1-CB 3.83Å; L98-A136 HydrophobicContact CG-CB 4.49Å; H132-A136 PolarHBondContact O-N 3.11Å; V133-A136 PolarHBondContact O-N 3.28Å; V133-A136 VanDerWaalsContact O-N 3.13Å; L134-A136 VanDerWaalsContact C-N 3.34Å; L134-A136 PolarHBondContact O-N 3.37Å; A136-M139 WeakPolarHBondContact O-CB 3.42Å; A136-M139 PolarHBondContact O-N 2.9Å; A136-V140 WeakPolarHBondContact O-CG2 3.37Å; A136-V140 PolarHBondContact O-N 3.28Å; A136-V140 VanDerWaalsContact O-N 3.1Å
137	C	94.4	Very high	92.5	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.7	-42.4	172.8	-71.2	0	0	0	0	112	V35 V39 L98 V133 L134 M139 V140 V141	V35-C137 HydrophobicContact CG1-CB 3.57Å; V39-C137 HydrophobicContact CG2-CB 3.35Å; V39-C137 WeakPolarHBondContact CG2-SG 3.09Å; L98-C137 WeakPolarHBondContact CD1-SG 3.14Å; V133-C137 PolarHBondContact O-N 2.65Å; V133-C137 PolarHBondContact O-SG 3.3Å; V133-C137 VanDerWaalsContact O-SG 3.35Å; L134-C137 WeakPolarHBondContact O-CB 3.33Å; L134-C137 PolarHBondContact O-N 2.92Å; C137-M139 VanDerWaalsContact C-N 3.25Å; C137-M139 PolarHBondContact O-N 3.39Å; C137-V140 PolarHBondContact O-N 2.93Å; C137-V141 WeakPolarHBondContact O-CG2 3.47Å; C137-V141 PolarHBondContact O-N 3.46Å
138	Q	91.4	Very high	91.9	Very high	81 Å²	81	40 Å²	40	38%	0.379	21%	0.209	S	C	.	.	H	α-helix	trans	-58.7	-38.8	174.3	-72.7	171.6	-22.6	0	0	111.6	L134 P135 T142 L154 L157	L134-Q138 WeakPolarHBondContact O-CG 3.33Å; L134-Q138 PolarHBondContact O-N 3.23Å; P135-Q138 WeakPolarHBondContact O-CB 3.43Å; P135-Q138 PolarHBondContact O-N 3.03Å; Q138-T142 VanDerWaalsContact O-CB 3.26Å; Q138-T142 WeakPolarHBondContact O-CB 3.25Å; Q138-T142 PolarHBondContact O-N 3.45Å; Q138-T142 PolarHBondContact O-OG1 2.74Å; Q138-L154 HydrophobicContact CB-CD2 4.17Å; Q138-L154 HydrophobicContact CG-CD2 4.09Å; Q138-L157 HydrophobicContact CG-CD1 3.51Å
139	M	89.8	Confident	91.6	Very high	39 Å²	39	45 Å²	45	19%	0.192	23%	0.231	C	C	.	.	H	α-helix	trans	-60.9	-50.1	173.7	-172.1	-172.7	-63.1	0	0	111.4	A94 P135 A136 C137 V141 T142 D143	A94-M139 HydrophobicContact CB-CB 4.39Å; A94-M139 HydrophobicContact CB-CG 3.96Å; A94-M139 HydrophobicContact CB-SD 3.64Å; P135-M139 PolarHBondContact O-N 3.06Å; A136-M139 WeakPolarHBondContact O-CB 3.42Å; A136-M139 PolarHBondContact O-N 2.9Å; C137-M139 VanDerWaalsContact C-N 3.25Å; C137-M139 PolarHBondContact O-N 3.39Å; M139-V141 PolarHBondContact O-N 2.72Å; M139-T142 PolarHBondContact O-N 3.5Å; M139-D143 WeakPolarHBondContact O-CB 3.48Å; M139-D143 PolarHBondContact O-N 3.5Å
140	V	93.3	Very high	91.1	Very high	0 Å²	0	48 Å²	48	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-60.3	-45.9	178.2	-178.8	0	0	0	0	111.6	V31 V35 A94 L98 A136 C137 T142 D143 L144 I203 T207	V31-V140 HydrophobicContact CG1-CG1 4.2Å; V35-V140 HydrophobicContact CG2-CB 4.06Å; V35-V140 HydrophobicContact CG2-CG1 3.64Å; A94-V140 HydrophobicContact CB-CG2 3.56Å; L98-V140 HydrophobicContact CD2-CG2 4.48Å; A136-V140 WeakPolarHBondContact O-CG2 3.37Å; A136-V140 PolarHBondContact O-N 3.28Å; A136-V140 VanDerWaalsContact O-N 3.1Å; C137-V140 PolarHBondContact O-N 2.93Å; V140-T142 VanDerWaalsContact C-N 3.33Å; V140-T142 PolarHBondContact O-N 3.08Å; V140-D143 PolarHBondContact O-N 2.87Å; V140-L144 HydrophobicContact CG1-CD1 3.76Å; V140-L144 HydrophobicContact CG1-CG 4.39Å; V140-L144 WeakPolarHBondContact O-CB 3.3Å; V140-L144 WeakPolarHBondContact O-CG 3.48Å; V140-L144 PolarHBondContact O-N 3.49Å; V140-L144 VanDerWaalsContact O-N 3.08Å; V140-I203 HydrophobicContact CG2-CG2 4.3Å; V140-T207 HydrophobicContact CG1-CG2 4.15Å; V140-T207 HydrophobicContact CG2-CG2 4.41Å
141	V	93.1	Very high	90.4	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-61.6	-43.8	179.1	172.4	0	0	0	0	110.5	V35 Y36 C137 M139 L144 T145 A153 L154	V35-V141 HydrophobicContact CB-CG2 4.38Å; V35-V141 HydrophobicContact CG1-CG2 3.75Å; Y36-V141 HydrophobicContact CE1-CG2 4.34Å; C137-V141 WeakPolarHBondContact O-CG2 3.47Å; C137-V141 PolarHBondContact O-N 3.46Å; M139-V141 PolarHBondContact O-N 2.72Å; V141-L144 PolarHBondContact O-N 2.65Å; V141-T145 WeakPolarHBondContact O-CB 3.21Å; V141-T145 PolarHBondContact O-N 3.01Å; V141-T145 PolarHBondContact O-OG1 3.4Å; V141-A153 HydrophobicContact CG1-CB 3.58Å; V141-L154 HydrophobicContact CB-CD2 4.37Å; V141-L154 HydrophobicContact CG1-CD2 4.11Å; V141-L154 HydrophobicContact CG1-CG 4.45Å
142	T	89	Confident	89.9	Confident	41 Å²	41	51.1 Å²	51.1	25%	0.252	27%	0.27	S	S	.	.	H	α-helix	trans	-66.6	-40	-180	-59.1	0	0	0	0	112.3	Q138 M139 V140 L144 R150	Q138-T142 VanDerWaalsContact O-CB 3.26Å; Q138-T142 WeakPolarHBondContact O-CB 3.25Å; Q138-T142 PolarHBondContact O-N 3.45Å; Q138-T142 PolarHBondContact O-OG1 2.74Å; M139-T142 PolarHBondContact O-N 3.5Å; V140-T142 VanDerWaalsContact C-N 3.33Å; V140-T142 PolarHBondContact O-N 3.08Å; T142-L144 VanDerWaalsContact C-N 3.33Å; T142-L144 PolarHBondContact O-N 3.25Å; T142-R150 PolarHBondContact O-NE 3.2Å; T142-R150 PolarHBondContact O-NH2 2.86Å
143	D	89.1	Confident	89.6	Confident	42 Å²	42	50.2 Å²	50.2	23%	0.225	27%	0.267	C	S	.	.	H	α-helix	trans	-65.5	-34.9	178.2	-80.8	-7.7	0	0	0	112.3	M139 V140 T207	M139-D143 WeakPolarHBondContact O-CB 3.48Å; M139-D143 PolarHBondContact O-N 3.5Å; V140-D143 PolarHBondContact O-N 2.87Å; D143-T207 WeakPolarHBondContact OD2-CB 3.47Å; D143-T207 PolarHBondContact OD2-OG1 2.96Å
144	L	90.4	Very high	89.2	Confident	27 Å²	27	52.9 Å²	52.9	14%	0.141	28%	0.281	C	S	.	.	H	α-helix	trans	-97.6	-7.5	-175.4	-62.2	-179.7	0	0	0	114.5	K28 V31 I32 V140 V141 T142	K28-L144 HydrophobicContact CG-CD2 4.47Å; V31-L144 HydrophobicContact CB-CD1 3.84Å; V31-L144 HydrophobicContact CG1-CD1 3.39Å; I32-L144 HydrophobicContact CD1-CB 4.14Å; I32-L144 HydrophobicContact CG1-CB 4.16Å; I32-L144 HydrophobicContact CG1-CD1 4.46Å; V140-L144 HydrophobicContact CG1-CD1 3.76Å; V140-L144 HydrophobicContact CG1-CG 4.39Å; V140-L144 WeakPolarHBondContact O-CB 3.3Å; V140-L144 WeakPolarHBondContact O-CG 3.48Å; V140-L144 PolarHBondContact O-N 3.49Å; V140-L144 VanDerWaalsContact O-N 3.08Å; V141-L144 PolarHBondContact O-N 2.65Å; T142-L144 VanDerWaalsContact C-N 3.33Å; T142-L144 PolarHBondContact O-N 3.25Å
145	T	90.1	Very high	88.7	Confident	16 Å²	16	54 Å²	54	10%	0.098	29%	0.293	C	S	.	.	S	Bend	trans	-108.6	133.7	-177.7	-51.9	0	0	0	0	111.2	V141 K149 R150 A153	V141-T145 WeakPolarHBondContact O-CB 3.21Å; V141-T145 PolarHBondContact O-N 3.01Å; V141-T145 PolarHBondContact O-OG1 3.4Å; T145-K149 HydrophobicContact CG2-CB 3.67Å; T145-R150 HydrophobicContact CG2-CG 4.16Å; T145-R150 PolarHBondContact O-NE 3.5Å; T145-R150 VanDerWaalsContact O-NE 3.11Å; T145-A153 HydrophobicContact CG2-CB 3.89Å
146	E	88.6	Confident	88.7	Confident	86 Å²	86	55.3 Å²	55.3	40%	0.402	29%	0.292	S	S	.	.			trans	-54.8	140.2	171.3	-68.8	167	-176.9	0	0	111.3	E148 K149 R150	E146-E148 PolarHBondContact O-N 2.89Å; E146-K149 PolarHBondContact O-N 3.44Å; E146-K149 WeakPolarHBondContact OE2-CE 3.1Å; E146-K149 IonicContact OE2-NZ 2.68Å; E146-K149 PolarHBondContact OE2-NZ 3.03Å; E146-R150 WeakPolarHBondContact O-CG 3.45Å; E146-R150 PolarHBondContact O-N 3.28Å
147	P	84.9	Confident	88.5	Confident	84 Å²	84	55.7 Å²	55.7	55%	0.545	29%	0.294	S	S	.	.	G	3₁₀ helix	trans	-47.6	-40.5	-175.5	-29.7	36.3	0	0	0	114.9	K149 R150	P147-K149 VanDerWaalsContact C-N 3.31Å; P147-K149 PolarHBondContact O-N 2.88Å; P147-R150 PolarHBondContact O-N 3.38Å
148	E	85.1	Confident	87.9	Confident	155 Å²	155	58 Å²	58	72%	0.724	32%	0.318	S	S	*	.	G	3₁₀ helix	trans	-69.7	-27.7	-176.9	-56.1	73	-155.7	0	0	112.4	E146	E146-E148 PolarHBondContact O-N 2.89Å
149	K	88.6	Confident	87.7	Confident	110 Å²	110	58.7 Å²	58.7	48%	0.478	32%	0.324	S	S	.	.	G	3₁₀ helix	trans	-98.8	-6.8	-178	-66.3	173.4	-175.4	149.1	0	113.2	T145 E146 P147 A151 D152 A153	T145-K149 HydrophobicContact CG2-CB 3.67Å; E146-K149 PolarHBondContact O-N 3.44Å; E146-K149 WeakPolarHBondContact OE2-CE 3.1Å; E146-K149 IonicContact OE2-NZ 2.68Å; E146-K149 PolarHBondContact OE2-NZ 3.03Å; P147-K149 VanDerWaalsContact C-N 3.31Å; P147-K149 PolarHBondContact O-N 2.88Å; K149-A151 VanDerWaalsContact C-N 3.33Å; K149-A151 PolarHBondContact O-N 2.85Å; K149-D152 PolarHBondContact O-N 3.45Å; K149-A153 PolarHBondContact O-N 3.32Å
150	R	85.7	Confident	87.8	Confident	90 Å²	90	57.3 Å²	57.3	34%	0.34	32%	0.318	S	S	.	.	H	α-helix	trans	-58.3	-41.7	-176.6	-78	176.2	-177.5	170.7	-4.8	112.9	T142 T145 E146 P147 D152 A153 L154	T142-R150 PolarHBondContact O-NE 3.2Å; T142-R150 PolarHBondContact O-NH2 2.86Å; T145-R150 HydrophobicContact CG2-CG 4.16Å; T145-R150 PolarHBondContact O-NE 3.5Å; T145-R150 VanDerWaalsContact O-NE 3.11Å; E146-R150 WeakPolarHBondContact O-CG 3.45Å; E146-R150 PolarHBondContact O-N 3.28Å; P147-R150 PolarHBondContact O-N 3.38Å; R150-D152 VanDerWaalsContact C-N 3.34Å; R150-D152 PolarHBondContact O-N 2.63Å; R150-A153 PolarHBondContact O-N 3.34Å; R150-L154 VanDerWaalsContact O-CB 3.3Å; R150-L154 WeakPolarHBondContact O-CB 3.32Å; R150-L154 VanDerWaalsContact O-CG 3.23Å; R150-L154 WeakPolarHBondContact O-CG 3.27Å; R150-L154 PolarHBondContact O-N 3.15Å
151	A	81.6	Confident	87.7	Confident	79 Å²	79	60.4 Å²	60.4	65%	0.653	33%	0.332	S	S	*	.	H	α-helix	trans	-61.2	-43.5	180	0	0	0	0	0	111.8	K149 S155	K149-A151 VanDerWaalsContact C-N 3.33Å; K149-A151 PolarHBondContact O-N 2.85Å; A151-S155 WeakPolarHBondContact O-CB 3.4Å; A151-S155 PolarHBondContact O-N 3.4Å
152	D	85.2	Confident	87.4	Confident	88 Å²	88	60.7 Å²	60.7	47%	0.471	33%	0.334	S	S	.	.	H	α-helix	trans	-68	-40.5	176.2	178.6	62.7	0	0	0	112.4	K149 R150 S155 K156	K149-D152 PolarHBondContact O-N 3.45Å; R150-D152 VanDerWaalsContact C-N 3.34Å; R150-D152 PolarHBondContact O-N 2.63Å; D152-S155 PolarHBondContact O-N 3.41Å; D152-S155 PolarHBondContact O-OG 2.91Å; D152-K156 WeakPolarHBondContact O-CG 3.42Å; D152-K156 PolarHBondContact O-N 3.3Å; D152-K156 IonicContact OD1-NZ 2.65Å; D152-K156 VanDerWaalsContact OD2-CE 3.32Å; D152-K156 WeakPolarHBondContact OD2-CE 3.48Å; D152-K156 IonicContact OD2-NZ 3.65Å; D152-K156 PolarHBondContact OD2-NZ 3.29Å
153	A	89.4	Confident	87.5	Confident	6 Å²	6	62.8 Å²	62.8	5%	0.05	34%	0.343	C	S	.	.	H	α-helix	trans	-67	-40.8	177.2	0	0	0	0	0	112.2	Y36 V141 T145 K149 R150	Y36-A153 WeakPolarHBondContact OH-CA 3.4Å; Y36-A153 PolarHBondContact OH-O 3.05Å; V141-A153 HydrophobicContact CG1-CB 3.58Å; T145-A153 HydrophobicContact CG2-CB 3.89Å; K149-A153 PolarHBondContact O-N 3.32Å; R150-A153 PolarHBondContact O-N 3.34Å
154	L	87	Confident	87.8	Confident	59 Å²	59	60.8 Å²	60.8	31%	0.309	33%	0.332	S	S	.	.	H	α-helix	trans	-71.5	-32.8	177.4	-69.2	171	0	0	0	112.1	Q138 V141 R150 K156 L157	Q138-L154 HydrophobicContact CB-CD2 4.17Å; Q138-L154 HydrophobicContact CG-CD2 4.09Å; V141-L154 HydrophobicContact CB-CD2 4.37Å; V141-L154 HydrophobicContact CG1-CD2 4.11Å; V141-L154 HydrophobicContact CG1-CG 4.45Å; R150-L154 VanDerWaalsContact O-CB 3.3Å; R150-L154 WeakPolarHBondContact O-CB 3.32Å; R150-L154 VanDerWaalsContact O-CG 3.23Å; R150-L154 WeakPolarHBondContact O-CG 3.27Å; R150-L154 PolarHBondContact O-N 3.15Å; L154-K156 VanDerWaalsContact C-N 3.29Å; L154-K156 PolarHBondContact O-N 3.36Å; L154-L157 HydrophobicContact CD2-CD1 3.85Å; L154-L157 VanDerWaalsContact O-CB 3.24Å; L154-L157 WeakPolarHBondContact O-CB 3.13Å; L154-L157 WeakPolarHBondContact O-CG 3.15Å; L154-L157 PolarHBondContact O-N 2.81Å; L154-L157 VanDerWaalsContact O-N 3.16Å
155	S	82.1	Confident	87.9	Confident	73 Å²	73	59.9 Å²	59.9	51%	0.51	33%	0.328	S	S	.	.	H	α-helix	trans	-65	-33.3	177.4	74.8	0	0	0	0	112.3	A151 D152 L157 G158	A151-S155 WeakPolarHBondContact O-CB 3.4Å; A151-S155 PolarHBondContact O-N 3.4Å; D152-S155 PolarHBondContact O-N 3.41Å; D152-S155 PolarHBondContact O-OG 2.91Å; S155-L157 PolarHBondContact O-N 3Å; S155-G158 PolarHBondContact O-N 3.44Å
156	K	90.2	Very high	88.1	Confident	86 Å²	86	61.4 Å²	61.4	37%	0.374	33%	0.334	S	S	.	.	H	α-helix	trans	-61.2	-23.5	174.7	-71.5	167.1	-170.9	160.7	0	113.2	Y36 D152 L154 G158 L159 C160	Y36-K156 HydrophobicContact CE1-CB 4Å; Y36-K156 HydrophobicContact CE2-CB 4.28Å; Y36-K156 HydrophobicContact CE2-CD 4.08Å; D152-K156 WeakPolarHBondContact O-CG 3.42Å; D152-K156 PolarHBondContact O-N 3.3Å; D152-K156 IonicContact OD1-NZ 2.65Å; D152-K156 VanDerWaalsContact OD2-CE 3.32Å; D152-K156 WeakPolarHBondContact OD2-CE 3.48Å; D152-K156 IonicContact OD2-NZ 3.65Å; D152-K156 PolarHBondContact OD2-NZ 3.29Å; L154-K156 VanDerWaalsContact C-N 3.29Å; L154-K156 PolarHBondContact O-N 3.36Å; K156-G158 PolarHBondContact O-N 2.99Å; K156-L159 WeakPolarHBondContact O-CB 3.49Å; K156-L159 PolarHBondContact O-N 3.43Å; K156-L159 VanDerWaalsContact O-N 3.14Å; K156-C160 PolarHBondContact O-N 3.31Å; K156-C160 PolarHBondContact O-SG 2.94Å
157	L	88.4	Confident	88.5	Confident	7 Å²	7	59.3 Å²	59.3	4%	0.037	33%	0.332	C	S	.	.	H	α-helix	trans	-63.2	-29.8	171.5	-58.8	176.9	0	0	0	112.4	Y36 V39 L134 Q138 L154 S155 L159 C160 F161	Y36-L157 HydrophobicContact CD1-CD2 3.69Å; Y36-L157 HydrophobicContact CE1-CD2 3.82Å; Y36-L157 HydrophobicContact CE1-CG 4.37Å; V39-L157 HydrophobicContact CB-CD2 4.39Å; V39-L157 HydrophobicContact CG1-CD2 4.32Å; V39-L157 HydrophobicContact CG2-CD2 3.95Å; L134-L157 HydrophobicContact CD1-CD1 4.45Å; Q138-L157 HydrophobicContact CG-CD1 3.51Å; L154-L157 HydrophobicContact CD2-CD1 3.85Å; L154-L157 VanDerWaalsContact O-CB 3.24Å; L154-L157 WeakPolarHBondContact O-CB 3.13Å; L154-L157 WeakPolarHBondContact O-CG 3.15Å; L154-L157 PolarHBondContact O-N 2.81Å; L154-L157 VanDerWaalsContact O-N 3.16Å; S155-L157 PolarHBondContact O-N 3Å; L157-L159 VanDerWaalsContact C-N 3.34Å; L157-C160 WeakPolarHBondContact O-CB 3.41Å; L157-C160 PolarHBondContact O-N 2.93Å; L157-F161 PolarHBondContact O-N 3.48Å
158	G	83.3	Confident	89	Confident	48 Å²	48	55.3 Å²	55.3	50%	0.495	31%	0.306	S	S	.	.	H	α-helix	trans	-64.6	-37	173.4	0	0	0	0	0	112.6	S155 K156 F161 G162	S155-G158 PolarHBondContact O-N 3.44Å; K156-G158 PolarHBondContact O-N 2.99Å; G158-F161 WeakPolarHBondContact O-CB 3.43Å; G158-F161 PolarHBondContact O-N 3.23Å; G158-G162 PolarHBondContact O-N 3.14Å
159	L	87.1	Confident	89.5	Confident	97 Å²	97	48 Å²	48	51%	0.508	27%	0.272	S	S	.	.	H	α-helix	trans	-65.9	-44.7	173.6	179.5	64	0	0	0	111.2	K156 L157 F161 G162 I163 M288	K156-L159 WeakPolarHBondContact O-CB 3.49Å; K156-L159 PolarHBondContact O-N 3.43Å; K156-L159 VanDerWaalsContact O-N 3.14Å; L157-L159 VanDerWaalsContact C-N 3.34Å; L159-F161 PolarHBondContact O-N 2.99Å; L159-G162 PolarHBondContact O-N 3.16Å; L159-I163 HydrophobicContact CD1-CD1 4.32Å; L159-I163 HydrophobicContact CG-CD1 4.01Å; L159-I163 WeakPolarHBondContact O-CG1 3.26Å; L159-I163 PolarHBondContact O-N 3.03Å; L159-M288 HydrophobicContact CD1-SD 4.18Å
160	C	92.6	Very high	89.8	Confident	10 Å²	10	44.9 Å²	44.9	7%	0.068	26%	0.262	C	S	.	.	H	α-helix	trans	-56.6	-38.8	174.3	-64.3	0	0	0	0	112	Y36 V39 S40 K156 L157 I163 G164	Y36-C160 PolarHBondContact O-SG 3.47Å; Y36-C160 VanDerWaalsContact O-SG 3.4Å; V39-C160 HydrophobicContact CB-CB 4.24Å; V39-C160 HydrophobicContact CG1-CB 3.75Å; S40-C160 VanDerWaalsContact OG-CB 3.28Å; S40-C160 WeakPolarHBondContact OG-CB 3.39Å; S40-C160 PolarHBondContact OG-SG 2.88Å; S40-C160 VanDerWaalsContact OG-SG 3.4Å; K156-C160 PolarHBondContact O-N 3.31Å; K156-C160 PolarHBondContact O-SG 2.94Å; L157-C160 WeakPolarHBondContact O-CB 3.41Å; L157-C160 PolarHBondContact O-N 2.93Å; C160-I163 PolarHBondContact O-N 2.91Å; C160-G164 PolarHBondContact O-N 2.83Å
161	F	89.4	Confident	90.3	Very high	65 Å²	65	43.5 Å²	43.5	29%	0.285	26%	0.261	S	S	.	.	H	α-helix	trans	-62.9	-46.7	177	-170.2	-89.3	0	0	0	112.2	I43 M46 F47 L157 G158 L159 G164 M165	I43-F161 HydrophobicContact CD1-CD2 3.51Å; I43-F161 HydrophobicContact CD1-CE2 3.72Å; I43-F161 HydrophobicContact CG1-CD2 3.8Å; I43-F161 HydrophobicContact CG1-CE2 4.43Å; I43-F161 HydrophobicContact CG2-CD2 4.01Å; I43-F161 HydrophobicContact CG2-CE2 4.31Å; I43-F161 HydrophobicContact CG2-CG 4.29Å; I43-F161 WeakPolarHBondContact CG2-O 3.36Å; M46-F161 HydrophobicContact CE-CE2 4.04Å; M46-F161 HydrophobicContact CE-CZ 4.32Å; F47-F161 HydrophobicContact CE2-CE1 4.32Å; F47-F161 HydrophobicContact CE2-CE2 4.49Å; F47-F161 HydrophobicContact CE2-CZ 4.01Å; F47-F161 HydrophobicContact CZ-CE1 4.46Å; F47-F161 HydrophobicContact CZ-CZ 4.24Å; L157-F161 PolarHBondContact O-N 3.48Å; G158-F161 WeakPolarHBondContact O-CB 3.43Å; G158-F161 PolarHBondContact O-N 3.23Å; L159-F161 PolarHBondContact O-N 2.99Å; F161-G164 PolarHBondContact O-N 3.2Å; F161-M165 HydrophobicContact CD1-CE 3.82Å; F161-M165 HydrophobicContact CE1-CE 3.23Å; F161-M165 HydrophobicContact CZ-CE 4.11Å; F161-M165 WeakPolarHBondContact O-CB 3.43Å; F161-M165 PolarHBondContact O-N 3.25Å
162	G	88.2	Confident	91	Very high	5 Å²	5	39.8 Å²	39.8	5%	0.052	23%	0.23	C	C	.	.	H	α-helix	trans	-60.5	-47	176.1	0	0	0	0	0	112.7	G158 L159 G164 M165 I166	G158-G162 PolarHBondContact O-N 3.14Å; L159-G162 PolarHBondContact O-N 3.16Å; G162-G164 PolarHBondContact O-N 3.27Å; G162-M165 PolarHBondContact O-N 2.82Å; G162-I166 WeakPolarHBondContact O-CG1 3.23Å; G162-I166 PolarHBondContact O-N 3.35Å; G162-I166 VanDerWaalsContact O-N 3.11Å
163	I	91.5	Very high	91.4	Very high	85 Å²	85	35.6 Å²	35.6	44%	0.436	21%	0.208	S	C	.	.	H	α-helix	trans	-59.5	-49.2	177.2	-66.5	169.1	0	0	0	110.6	L159 C160 M165 I166 A167	L159-I163 HydrophobicContact CD1-CD1 4.32Å; L159-I163 HydrophobicContact CG-CD1 4.01Å; L159-I163 WeakPolarHBondContact O-CG1 3.26Å; L159-I163 PolarHBondContact O-N 3.03Å; C160-I163 PolarHBondContact O-N 2.91Å; I163-M165 VanDerWaalsContact C-N 3.33Å; I163-M165 PolarHBondContact O-N 3.31Å; I163-I166 PolarHBondContact O-N 3.4Å; I163-A167 WeakPolarHBondContact O-CB 3.43Å; I163-A167 PolarHBondContact O-N 2.86Å
164	G	94.9	Very high	91.7	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-63.1	-38.1	179.6	0	0	0	0	0	112.6	T44 C160 F161 G162 G168	T44-G164 WeakPolarHBondContact CA-O 3.31Å; T44-G164 WeakPolarHBondContact OG1-CA 3.45Å; C160-G164 PolarHBondContact O-N 2.83Å; F161-G164 PolarHBondContact O-N 3.2Å; G162-G164 PolarHBondContact O-N 3.27Å; G164-G168 WeakPolarHBondContact O-CA 3.41Å; G164-G168 PolarHBondContact O-N 2.9Å
165	M	92.3	Very high	92.1	Very high	9 Å²	9	35 Å²	35	4%	0.044	20%	0.204	C	C	.	.	H	α-helix	trans	-61.5	-48.4	176.7	-178.3	175.5	-34.1	0	0	112	F47 F161 G162 I163 S169 G284 Q287	F47-M165 HydrophobicContact CD1-CB 4.43Å; F47-M165 HydrophobicContact CD1-CG 3.7Å; F47-M165 VanDerWaalsContact CD2-CA 3.46Å; F47-M165 HydrophobicContact CD2-CB 3.77Å; F47-M165 HydrophobicContact CD2-CG 3.93Å; F47-M165 HydrophobicContact CE1-CB 4.34Å; F47-M165 HydrophobicContact CE1-CE 4.11Å; F47-M165 HydrophobicContact CE1-CG 3.48Å; F47-M165 VanDerWaalsContact CE1-CG 3.48Å; F47-M165 HydrophobicContact CE1-SD 3.78Å; F47-M165 HydrophobicContact CE2-CB 3.62Å; F47-M165 HydrophobicContact CE2-CE 3.85Å; F47-M165 HydrophobicContact CE2-CG 3.7Å; F47-M165 HydrophobicContact CE2-SD 4.35Å; F47-M165 HydrophobicContact CG-CB 4.18Å; F47-M165 HydrophobicContact CG-CG 3.93Å; F47-M165 HydrophobicContact CZ-CB 3.96Å; F47-M165 HydrophobicContact CZ-CE 3.38Å; F47-M165 HydrophobicContact CZ-CG 3.5Å; F47-M165 VanDerWaalsContact CZ-CG 3.5Å; F47-M165 HydrophobicContact CZ-SD 3.68Å; F161-M165 HydrophobicContact CD1-CE 3.82Å; F161-M165 HydrophobicContact CE1-CE 3.23Å; F161-M165 HydrophobicContact CZ-CE 4.11Å; F161-M165 WeakPolarHBondContact O-CB 3.43Å; F161-M165 PolarHBondContact O-N 3.25Å; G162-M165 PolarHBondContact O-N 2.82Å; I163-M165 VanDerWaalsContact C-N 3.33Å; I163-M165 PolarHBondContact O-N 3.31Å; M165-S169 WeakPolarHBondContact O-CB 3.38Å; M165-S169 PolarHBondContact O-N 3.18Å; M165-S169 PolarHBondContact O-OG 2.95Å; M165-G284 WeakPolarHBondContact SD-CA 3.5Å; M165-Q287 VanDerWaalsContact CE-OE1 3.31Å
166	I	94.1	Very high	92.7	Very high	47 Å²	47	31.7 Å²	31.7	24%	0.241	18%	0.181	C	C	.	.	H	α-helix	trans	-64.6	-50.2	-179.4	-64.5	164.8	0	0	0	109.9	G162 I163 T170 A281 I285	G162-I166 WeakPolarHBondContact O-CG1 3.23Å; G162-I166 PolarHBondContact O-N 3.35Å; G162-I166 VanDerWaalsContact O-N 3.11Å; I163-I166 PolarHBondContact O-N 3.4Å; I166-T170 VanDerWaalsContact O-CB 3.25Å; I166-T170 WeakPolarHBondContact O-CB 3.29Å; I166-T170 PolarHBondContact O-N 3.39Å; I166-T170 PolarHBondContact O-OG1 3.12Å; I166-A281 HydrophobicContact CG2-CB 4.35Å; I166-I285 HydrophobicContact CD1-CG1 3.57Å; I166-I285 HydrophobicContact CG1-CG1 3.96Å
167	A	96.4	Very high	92.8	Very high	43 Å²	43	31.7 Å²	31.7	36%	0.355	18%	0.183	S	C	.	.	H	α-helix	trans	-62.6	-49.9	-179.3	0	0	0	0	0	111.4	T44 I163 L171	T44-A167 HydrophobicContact CG2-CB 4.16Å; I163-A167 WeakPolarHBondContact O-CB 3.43Å; I163-A167 PolarHBondContact O-N 2.86Å; A167-L171 WeakPolarHBondContact O-CB 3.28Å; A167-L171 PolarHBondContact O-N 2.98Å
168	G	96.5	Very high	93	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-64.3	-46	-176.4	0	0	0	0	0	113.2	T44 L48 G164 L171 G172	T44-G168 WeakPolarHBondContact O-CA 3.49Å; L48-G168 WeakPolarHBondContact CA-O 3.47Å; L48-G168 PolarHBondContact N-O 3.49Å; G164-G168 WeakPolarHBondContact O-CA 3.41Å; G164-G168 PolarHBondContact O-N 2.9Å; G168-L171 PolarHBondContact O-N 3.45Å; G168-G172 PolarHBondContact O-N 2.93Å
169	S	94.8	Very high	93.6	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-64.9	-44.9	-179.5	-55.5	0	0	0	0	111.5	F47 S51 M165 G173 G277 M280	F47-S169 WeakPolarHBondContact CD1-OG 3.29Å; S51-S169 PolarHBondContact OG-O 3.36Å; M165-S169 WeakPolarHBondContact O-CB 3.38Å; M165-S169 PolarHBondContact O-N 3.18Å; M165-S169 PolarHBondContact O-OG 2.95Å; S169-G173 PolarHBondContact O-N 2.82Å; S169-G277 VanDerWaalsContact CB-O 3.28Å; S169-G277 WeakPolarHBondContact CB-O 3.38Å; S169-G277 WeakPolarHBondContact O-CA 3.21Å; S169-M280 WeakPolarHBondContact OG-CB 3.44Å
170	T	95.2	Very high	93.9	Very high	45 Å²	45	41 Å²	41	28%	0.276	21%	0.205	S	C	.	.	H	α-helix	trans	-64.3	-47.9	178.1	-56.7	0	0	0	0	111.2	I166 N174 Y278	I166-T170 VanDerWaalsContact O-CB 3.25Å; I166-T170 WeakPolarHBondContact O-CB 3.29Å; I166-T170 PolarHBondContact O-N 3.39Å; I166-T170 PolarHBondContact O-OG1 3.12Å; T170-N174 WeakPolarHBondContact O-CB 3.19Å; T170-N174 PolarHBondContact O-N 2.96Å; T170-N174 PolarHBondContact O-ND2 3.43Å; T170-Y278 HydrophobicContact CG2-CD1 4.43Å; T170-Y278 HydrophobicContact CG2-CE1 4.06Å
171	L	96.6	Very high	94	Very high	62 Å²	62	42 Å²	42	33%	0.325	21%	0.208	S	C	.	.	H	α-helix	trans	-63.5	-49.7	-179.7	-173.2	68.1	0	0	0	110.9	T44 W45 L48 A167 G168 G173 N174 I175	T44-L171 HydrophobicContact CG2-CD2 4.45Å; W45-L171 HydrophobicContact CZ3-CD2 3.95Å; L48-L171 HydrophobicContact CD1-CD2 4.06Å; L48-L171 HydrophobicContact CD1-CG 4.25Å; A167-L171 WeakPolarHBondContact O-CB 3.28Å; A167-L171 PolarHBondContact O-N 2.98Å; G168-L171 PolarHBondContact O-N 3.45Å; L171-G173 PolarHBondContact O-N 3.33Å; L171-N174 PolarHBondContact O-N 3.31Å; L171-I175 HydrophobicContact CD1-CD1 3.49Å; L171-I175 VanDerWaalsContact CD1-CD1 3.49Å; L171-I175 HydrophobicContact CD1-CG1 4.07Å; L171-I175 HydrophobicContact CD2-CD1 4.48Å; L171-I175 HydrophobicContact CG-CD1 3.69Å; L171-I175 HydrophobicContact CG-CG1 4.37Å; L171-I175 WeakPolarHBondContact O-CB 3.43Å; L171-I175 VanDerWaalsContact O-CG1 3.26Å; L171-I175 WeakPolarHBondContact O-CG1 3.1Å; L171-I175 PolarHBondContact O-N 3.35Å
172	G	95.1	Very high	94.3	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-61	-44.3	179.9	0	0	0	0	0	112.7	G168 S176	G168-G172 PolarHBondContact O-N 2.93Å; G172-S176 WeakPolarHBondContact O-CB 3.48Å; G172-S176 PolarHBondContact O-N 3.48Å; G172-S176 PolarHBondContact O-OG 2.85Å
173	G	93.9	Very high	94.7	Very high	0 Å²	0	46.6 Å²	46.6	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-64.7	-47.5	177.7	0	0	0	0	0	113	S169 L171 M177 A273 Q274	S169-G173 PolarHBondContact O-N 2.82Å; L171-G173 PolarHBondContact O-N 3.33Å; G173-M177 WeakPolarHBondContact O-CB 3.42Å; G173-M177 PolarHBondContact O-N 3.49Å; G173-M177 VanDerWaalsContact O-N 3.12Å; G173-A273 WeakPolarHBondContact CA-O 3.32Å; G173-Q274 WeakPolarHBondContact O-CA 3.34Å; G173-Q274 PolarHBondContact O-N 3.04Å
174	N	95.9	Very high	94.9	Very high	30 Å²	30	42.6 Å²	42.6	16%	0.16	21%	0.212	C	C	.	.	H	α-helix	trans	-65.7	-45.2	-179.5	-85	-86.1	0	0	0	112.6	T170 L171 M177 R178 Q274 Y278	T170-N174 WeakPolarHBondContact O-CB 3.19Å; T170-N174 PolarHBondContact O-N 2.96Å; T170-N174 PolarHBondContact O-ND2 3.43Å; L171-N174 PolarHBondContact O-N 3.31Å; N174-M177 PolarHBondContact O-N 2.6Å; N174-R178 WeakPolarHBondContact O-CG 3.34Å; N174-R178 PolarHBondContact O-N 2.72Å; N174-Q274 PolarHBondContact OD1-NE2 3.44Å; N174-Y278 WeakPolarHBondContact ND2-CE1 3.49Å; N174-Y278 PolarHBondContact ND2-OH 2.7Å; N174-Y278 PolarHBondContact OD1-OH 3.22Å
175	I	96.3	Very high	95	Very high	22 Å²	22	42.6 Å²	42.6	11%	0.113	21%	0.212	C	C	.	.	H	α-helix	trans	-67.5	-43.2	-179.5	-66.4	-176.8	0	0	0	110.3	L171 M177 R178 Y179 G180 F183 A184 V187	L171-I175 HydrophobicContact CD1-CD1 3.49Å; L171-I175 VanDerWaalsContact CD1-CD1 3.49Å; L171-I175 HydrophobicContact CD1-CG1 4.07Å; L171-I175 HydrophobicContact CD2-CD1 4.48Å; L171-I175 HydrophobicContact CG-CD1 3.69Å; L171-I175 HydrophobicContact CG-CG1 4.37Å; L171-I175 WeakPolarHBondContact O-CB 3.43Å; L171-I175 VanDerWaalsContact O-CG1 3.26Å; L171-I175 WeakPolarHBondContact O-CG1 3.1Å; L171-I175 PolarHBondContact O-N 3.35Å; I175-M177 VanDerWaalsContact C-N 3.29Å; I175-M177 PolarHBondContact O-N 3.17Å; I175-R178 PolarHBondContact O-N 2.89Å; I175-Y179 HydrophobicContact CG2-CD2 4.23Å; I175-Y179 WeakPolarHBondContact O-CA 3.44Å; I175-Y179 PolarHBondContact O-N 3.49Å; I175-G180 PolarHBondContact O-N 3.09Å; I175-F183 HydrophobicContact CG2-CD1 3.54Å; I175-F183 HydrophobicContact CG2-CE1 4.05Å; I175-A184 HydrophobicContact CB-CB 4.26Å; I175-A184 HydrophobicContact CG2-CB 3.76Å; I175-V187 HydrophobicContact CD1-CB 4.42Å; I175-V187 HydrophobicContact CD1-CG1 4.06Å; I175-V187 HydrophobicContact CD1-CG2 4.18Å
176	S	93.4	Very high	95.3	Very high	4 Å²	4	45 Å²	45	3%	0.028	23%	0.229	C	C	.	.	H	α-helix	trans	-59.3	-42.9	178.1	-58	0	0	0	0	111.6	V52 G172 G180	V52-S176 VanDerWaalsContact CG2-OG 3.26Å; V52-S176 WeakPolarHBondContact CG2-OG 3.48Å; G172-S176 WeakPolarHBondContact O-CB 3.48Å; G172-S176 PolarHBondContact O-N 3.48Å; G172-S176 PolarHBondContact O-OG 2.85Å; S176-G180 CarbonylContact O-C 3.57Å; S176-G180 WeakPolarHBondContact O-CA 3.44Å; S176-G180 PolarHBondContact O-N 3.48Å
177	M	92.2	Very high	95.5	Very high	87 Å²	87	44.5 Å²	44.5	43%	0.429	23%	0.228	S	C	.	.	H	α-helix	trans	-68.3	-44.7	179.1	-175.2	54.2	-113.9	0	0	112.4	G173 N174 I175 Q274	G173-M177 WeakPolarHBondContact O-CB 3.42Å; G173-M177 PolarHBondContact O-N 3.49Å; G173-M177 VanDerWaalsContact O-N 3.12Å; N174-M177 PolarHBondContact O-N 2.6Å; I175-M177 VanDerWaalsContact C-N 3.29Å; I175-M177 PolarHBondContact O-N 3.17Å; M177-Q274 HydrophobicContact CB-CB 3.98Å; M177-Q274 HydrophobicContact CG-CB 4.31Å
178	R	94.3	Very high	95.6	Very high	175 Å²	175	42.4 Å²	42.4	66%	0.66	21%	0.211	S	C	*	.	H	α-helix	trans	-80.9	-34.4	-174.5	-67.9	-175.8	-176.9	-165.5	1	114.3	N174 I175	N174-R178 WeakPolarHBondContact O-CG 3.34Å; N174-R178 PolarHBondContact O-N 2.72Å; I175-R178 PolarHBondContact O-N 2.89Å
179	Y	95.1	Very high	95.7	Very high	150 Å²	150	42.7 Å²	42.7	59%	0.588	21%	0.213	S	C	*	.	H	α-helix	trans	-127.6	-2.3	-168.4	-56	-72.9	0	0	0	113.4	I175 F183	I175-Y179 HydrophobicContact CG2-CD2 4.23Å; I175-Y179 WeakPolarHBondContact O-CA 3.44Å; I175-Y179 PolarHBondContact O-N 3.49Å; Y179-F183 VanDerWaalsContact CB-CD1 3.41Å; Y179-F183 HydrophobicContact CD2-CD1 4.21Å; Y179-F183 HydrophobicContact CD2-CE1 4.17Å; Y179-F183 AromaticContact CG-CD1 3.93Å; Y179-F183 HydrophobicContact CG-CD1 3.93Å; Y179-F183 HydrophobicContact CG-CE1 4.12Å; Y179-F183 WeakPolarHBondContact O-CB 3.48Å
180	G	94.2	Very high	95.8	Very high	23 Å²	23	45.8 Å²	45.8	24%	0.237	24%	0.239	C	C	.	.			trans	88.1	161.9	-179.7	0	0	0	0	0	114.4	I175 S176 T182 F183 A184	I175-G180 PolarHBondContact O-N 3.09Å; S176-G180 CarbonylContact O-C 3.57Å; S176-G180 WeakPolarHBondContact O-CA 3.44Å; S176-G180 PolarHBondContact O-N 3.48Å; G180-T182 PolarHBondContact O-N 2.9Å; G180-F183 PolarHBondContact O-N 2.76Å; G180-A184 PolarHBondContact O-N 3.09Å
181	E	94.1	Very high	96	Very high	31 Å²	31	44.1 Å²	44.1	15%	0.145	23%	0.23	C	C	.	.	H	α-helix	trans	-66.7	-37	-175	-59.4	81.4	-173	0	0	112.5	V52 L56 K59 A184 A185	V52-E181 HydrophobicContact CG1-CB 3.73Å; V52-E181 HydrophobicContact CG1-CG 4.25Å; L56-E181 HydrophobicContact CB-CB 3.99Å; L56-E181 HydrophobicContact CB-CG 4.11Å; L56-E181 HydrophobicContact CD1-CB 4.24Å; L56-E181 HydrophobicContact CG-CB 4.49Å; K59-E181 IonicContact NZ-OE2 2.73Å; E181-A184 WeakPolarHBondContact O-CB 3.5Å; E181-A184 PolarHBondContact O-N 3.26Å; E181-A185 PolarHBondContact O-N 3.37Å
182	T	94.9	Very high	96	Very high	66 Å²	66	41.2 Å²	41.2	41%	0.405	22%	0.215	S	C	.	.	H	α-helix	trans	-61.1	-44.8	176.7	-61.4	0	0	0	0	111.5	A113 G180 A184 A185 C186	A113-T182 WeakPolarHBondContact O-CG2 3.15Å; G180-T182 PolarHBondContact O-N 2.9Å; T182-A184 VanDerWaalsContact C-N 3.35Å; T182-A185 WeakPolarHBondContact O-CB 3.36Å; T182-A185 PolarHBondContact O-N 3.34Å; T182-C186 PolarHBondContact O-N 3.22Å; T182-C186 PolarHBondContact O-SG 3.4Å; T182-C186 VanDerWaalsContact O-SG 3.39Å
183	F	96.8	Very high	96.2	Very high	100 Å²	100	42.9 Å²	42.9	44%	0.439	23%	0.229	S	C	.	.	H	α-helix	trans	-66.8	-39.2	177.9	-175.5	-99.3	0	0	0	111.1	I175 Y179 G180 A185 C186 V187	I175-F183 HydrophobicContact CG2-CD1 3.54Å; I175-F183 HydrophobicContact CG2-CE1 4.05Å; Y179-F183 VanDerWaalsContact CB-CD1 3.41Å; Y179-F183 HydrophobicContact CD2-CD1 4.21Å; Y179-F183 HydrophobicContact CD2-CE1 4.17Å; Y179-F183 AromaticContact CG-CD1 3.93Å; Y179-F183 HydrophobicContact CG-CD1 3.93Å; Y179-F183 HydrophobicContact CG-CE1 4.12Å; Y179-F183 WeakPolarHBondContact O-CB 3.48Å; G180-F183 PolarHBondContact O-N 2.76Å; F183-A185 VanDerWaalsContact C-N 3.32Å; F183-A185 PolarHBondContact O-N 2.78Å; F183-C186 WeakPolarHBondContact O-CB 3.48Å; F183-C186 PolarHBondContact O-N 3.13Å; F183-V187 HydrophobicContact CD1-CG2 4.21Å; F183-V187 HydrophobicContact CE1-CG2 3.87Å; F183-V187 HydrophobicContact CZ-CG2 4.23Å; F183-V187 WeakPolarHBondContact O-CG2 3.38Å; F183-V187 PolarHBondContact O-N 3.34Å
184	A	96.9	Very high	96.4	Very high	0 Å²	0	48 Å²	48	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-59.6	-41.4	172.6	0	0	0	0	0	112.3	V52 I175 G180 E181 T182 V187 G188	V52-A184 HydrophobicContact CG1-CB 4.32Å; V52-A184 HydrophobicContact CG2-CB 3.53Å; I175-A184 HydrophobicContact CB-CB 4.26Å; I175-A184 HydrophobicContact CG2-CB 3.76Å; G180-A184 PolarHBondContact O-N 3.09Å; E181-A184 WeakPolarHBondContact O-CB 3.5Å; E181-A184 PolarHBondContact O-N 3.26Å; T182-A184 VanDerWaalsContact C-N 3.35Å; A184-V187 PolarHBondContact O-N 3.35Å; A184-G188 PolarHBondContact O-N 2.9Å
185	A	97	Very high	96.5	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-63.5	-40.3	174.5	0	0	0	0	0	112.4	L112 A113 E181 T182 F183 V187 G188 A189	L112-A185 HydrophobicContact CB-CB 4.21Å; L112-A185 HydrophobicContact CD2-CB 3.97Å; L112-A185 HydrophobicContact CG-CB 3.86Å; A113-A185 HydrophobicContact CB-CB 3.86Å; E181-A185 PolarHBondContact O-N 3.37Å; T182-A185 WeakPolarHBondContact O-CB 3.36Å; T182-A185 PolarHBondContact O-N 3.34Å; F183-A185 VanDerWaalsContact C-N 3.32Å; F183-A185 PolarHBondContact O-N 2.78Å; A185-V187 VanDerWaalsContact C-N 3.34Å; A185-V187 PolarHBondContact O-N 3.33Å; A185-G188 PolarHBondContact O-N 3.22Å; A185-A189 PolarHBondContact O-N 2.87Å
186	C	97.9	Very high	96.6	Very high	59 Å²	59	47.5 Å²	47.5	40%	0.399	25%	0.249	S	C	.	.	H	α-helix	trans	-60.9	-40.7	172.7	-69.1	0	0	0	0	112.4	T182 F183 G188 A189 A190	T182-C186 PolarHBondContact O-N 3.22Å; T182-C186 PolarHBondContact O-SG 3.4Å; T182-C186 VanDerWaalsContact O-SG 3.39Å; F183-C186 WeakPolarHBondContact O-CB 3.48Å; F183-C186 PolarHBondContact O-N 3.13Å; C186-G188 VanDerWaalsContact C-N 3.34Å; C186-A189 WeakPolarHBondContact O-CB 3.35Å; C186-A189 PolarHBondContact O-N 3.1Å; C186-A190 PolarHBondContact O-N 3.48Å
187	V	98.1	Very high	96.8	Very high	37 Å²	37	51.7 Å²	51.7	22%	0.224	27%	0.27	C	S	.	.	H	α-helix	trans	-62.5	-42.8	174.4	172	0	0	0	0	110.8	L48 I175 F183 A184 A185 A189 A190 G191	L48-V187 HydrophobicContact CD1-CG1 4.44Å; I175-V187 HydrophobicContact CD1-CB 4.42Å; I175-V187 HydrophobicContact CD1-CG1 4.06Å; I175-V187 HydrophobicContact CD1-CG2 4.18Å; F183-V187 HydrophobicContact CD1-CG2 4.21Å; F183-V187 HydrophobicContact CE1-CG2 3.87Å; F183-V187 HydrophobicContact CZ-CG2 4.23Å; F183-V187 WeakPolarHBondContact O-CG2 3.38Å; F183-V187 PolarHBondContact O-N 3.34Å; A184-V187 PolarHBondContact O-N 3.35Å; A185-V187 VanDerWaalsContact C-N 3.34Å; A185-V187 PolarHBondContact O-N 3.33Å; V187-A189 VanDerWaalsContact C-N 3.35Å; V187-A189 PolarHBondContact O-N 3.19Å; V187-A190 PolarHBondContact O-N 3.06Å; V187-G191 PolarHBondContact O-N 3.07Å
188	G	97.8	Very high	97.1	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-60.9	-39.7	172.7	0	0	0	0	0	113.2	A184 A185 C186 S192	A184-G188 PolarHBondContact O-N 2.9Å; A185-G188 PolarHBondContact O-N 3.22Å; C186-G188 VanDerWaalsContact C-N 3.34Å; G188-S192 WeakPolarHBondContact O-CB 3.28Å; G188-S192 PolarHBondContact O-N 3.28Å; G188-S192 PolarHBondContact O-OG 3.06Å
189	A	98.3	Very high	97.2	Very high	6 Å²	6	40.2 Å²	40.2	5%	0.05	22%	0.224	C	C	.	.	H	α-helix	trans	-63.6	-48.9	175.2	0	0	0	0	0	111.6	F109 L110 A185 C186 V187 G191 S192 A193	F109-A189 HydrophobicContact CB-CB 3.72Å; L110-A189 HydrophobicContact CD2-CB 3.76Å; L110-A189 HydrophobicContact CG-CB 4Å; A185-A189 PolarHBondContact O-N 2.87Å; C186-A189 WeakPolarHBondContact O-CB 3.35Å; C186-A189 PolarHBondContact O-N 3.1Å; V187-A189 VanDerWaalsContact C-N 3.35Å; V187-A189 PolarHBondContact O-N 3.19Å; A189-G191 PolarHBondContact O-N 3.12Å; A189-S192 PolarHBondContact O-N 3.4Å; A189-S192 PolarHBondContact O-OG 3.33Å; A189-A193 VanDerWaalsContact O-CB 3.31Å; A189-A193 WeakPolarHBondContact O-CB 3.47Å; A189-A193 PolarHBondContact O-N 2.95Å
190	A	98.4	Very high	97.3	Very high	65 Å²	65	36.4 Å²	36.4	54%	0.537	21%	0.213	S	C	.	.	H	α-helix	trans	-62.9	-43.1	178	0	0	0	0	0	112	C186 V187 A193 F194	C186-A190 PolarHBondContact O-N 3.48Å; V187-A190 PolarHBondContact O-N 3.06Å; A190-A193 PolarHBondContact O-N 2.92Å; A190-F194 WeakPolarHBondContact O-CB 3.38Å; A190-F194 PolarHBondContact O-N 3.35Å
191	G	97.9	Very high	97.4	Very high	9 Å²	9	41 Å²	41	9%	0.093	23%	0.232	C	C	.	.	H	α-helix	trans	-66	-40.6	178.7	0	0	0	0	0	113.6	W45 V187 A189 F194 S195	W45-G191 VanDerWaalsContact CE2-C 3.46Å; W45-G191 PolarHBondContact NE1-O 3.44Å; V187-G191 PolarHBondContact O-N 3.07Å; A189-G191 PolarHBondContact O-N 3.12Å; G191-F194 WeakPolarHBondContact O-CB 3.47Å; G191-F194 PolarHBondContact O-N 3.04Å; G191-S195 PolarHBondContact O-N 2.93Å; G191-S195 PolarHBondContact O-OG 3.2Å
192	S	97.7	Very high	97.5	Very high	1 Å²	1	43.1 Å²	43.1	1%	0.007	24%	0.241	C	C	.	.	H	α-helix	trans	-70.2	-36.4	174.7	55.6	0	0	0	0	112.2	T106 G188 A189 F194 S195 L196	T106-S192 WeakPolarHBondContact CA-OG 3.41Å; T106-S192 PolarHBondContact N-OG 3.15Å; T106-S192 VanDerWaalsContact OG1-C 3.26Å; T106-S192 WeakPolarHBondContact OG1-CB 3.46Å; T106-S192 PolarHBondContact OG1-OG 3.5Å; G188-S192 WeakPolarHBondContact O-CB 3.28Å; G188-S192 PolarHBondContact O-N 3.28Å; G188-S192 PolarHBondContact O-OG 3.06Å; A189-S192 PolarHBondContact O-N 3.4Å; A189-S192 PolarHBondContact O-OG 3.33Å; S192-F194 VanDerWaalsContact C-N 3.34Å; S192-S195 WeakPolarHBondContact O-CB 3.18Å; S192-S195 PolarHBondContact O-N 3.35Å; S192-S195 VanDerWaalsContact O-N 3.14Å; S192-L196 PolarHBondContact O-N 3.41Å
193	A	98.4	Very high	97.5	Very high	35 Å²	35	40 Å²	40	29%	0.289	22%	0.222	S	C	.	.	H	α-helix	trans	-64	-40.2	172.4	0	0	0	0	0	111.3	T106 A189 A190 S195 L196 L197	T106-A193 HydrophobicContact CG2-CB 4.06Å; T106-A193 PolarHBondContact OG1-N 2.92Å; T106-A193 VanDerWaalsContact OG1-N 3.13Å; A189-A193 VanDerWaalsContact O-CB 3.31Å; A189-A193 WeakPolarHBondContact O-CB 3.47Å; A189-A193 PolarHBondContact O-N 2.95Å; A190-A193 PolarHBondContact O-N 2.92Å; A193-S195 VanDerWaalsContact C-N 3.3Å; A193-S195 PolarHBondContact O-N 3.47Å; A193-L196 WeakPolarHBondContact O-CB 3.47Å; A193-L196 PolarHBondContact O-N 2.89Å; A193-L197 WeakPolarHBondContact O-CG 3.47Å; A193-L197 PolarHBondContact O-N 2.95Å
194	F	98.5	Very high	97.2	Very high	109 Å²	109	37.3 Å²	37.3	48%	0.478	21%	0.214	S	C	.	.	H	α-helix	trans	-61.1	-40.2	171.7	179.6	-104.9	0	0	0	112	L41 A190 G191 S192 L196 L197 L198	L41-F194 HydrophobicContact CD1-CD1 4.06Å; L41-F194 HydrophobicContact CD1-CE1 4.19Å; A190-F194 WeakPolarHBondContact O-CB 3.38Å; A190-F194 PolarHBondContact O-N 3.35Å; G191-F194 WeakPolarHBondContact O-CB 3.47Å; G191-F194 PolarHBondContact O-N 3.04Å; S192-F194 VanDerWaalsContact C-N 3.34Å; F194-L196 VanDerWaalsContact C-N 3.33Å; F194-L196 PolarHBondContact O-N 3.02Å; F194-L197 WeakPolarHBondContact O-CB 3.46Å; F194-L197 PolarHBondContact O-N 3.46Å; F194-L197 VanDerWaalsContact O-N 3.15Å; F194-L198 HydrophobicContact CD1-CD1 4.24Å; F194-L198 HydrophobicContact CD1-CG 4.43Å; F194-L198 HydrophobicContact CE1-CD1 3.78Å; F194-L198 HydrophobicContact CE1-CD2 4.3Å; F194-L198 HydrophobicContact CE1-CG 4.05Å; F194-L198 HydrophobicContact CZ-CD1 4.37Å; F194-L198 HydrophobicContact CZ-CD2 4.06Å; F194-L198 HydrophobicContact CZ-CG 4.24Å; F194-L198 PolarHBondContact O-N 2.96Å
195	S	98	Very high	96.7	Very high	3 Å²	3	45.8 Å²	45.8	2%	0.021	25%	0.251	C	S	.	.	H	α-helix	trans	-61.9	-41.6	174.8	-51.5	0	0	0	0	111.2	W45 G191 S192 A193 L197 L198 V199	W45-S195 PolarHBondContact NE1-OG 3.19Å; G191-S195 PolarHBondContact O-N 2.93Å; G191-S195 PolarHBondContact O-OG 3.2Å; S192-S195 WeakPolarHBondContact O-CB 3.18Å; S192-S195 PolarHBondContact O-N 3.35Å; S192-S195 VanDerWaalsContact O-N 3.14Å; A193-S195 VanDerWaalsContact C-N 3.3Å; A193-S195 PolarHBondContact O-N 3.47Å; S195-L197 PolarHBondContact O-N 3.24Å; S195-L198 WeakPolarHBondContact O-CB 3.24Å; S195-L198 PolarHBondContact O-N 3.16Å; S195-V199 WeakPolarHBondContact O-CG2 3.44Å; S195-V199 PolarHBondContact O-N 3.38Å
196	L	98.3	Very high	96	Very high	37 Å²	37	48.3 Å²	48.3	19%	0.194	27%	0.269	C	S	.	.	H	α-helix	trans	-60	-42.1	172.3	175.9	60.3	0	0	0	112.1	S99 C102 A103 S192 A193 F194 L198 V199 L200	S99-L196 WeakPolarHBondContact O-CD1 3.46Å; C102-L196 HydrophobicContact CB-CB 3.83Å; C102-L196 HydrophobicContact CB-CD1 4.21Å; A103-L196 HydrophobicContact CB-CD2 4.05Å; S192-L196 PolarHBondContact O-N 3.41Å; A193-L196 WeakPolarHBondContact O-CB 3.47Å; A193-L196 PolarHBondContact O-N 2.89Å; F194-L196 VanDerWaalsContact C-N 3.33Å; F194-L196 PolarHBondContact O-N 3.02Å; L196-L198 VanDerWaalsContact C-N 3.34Å; L196-L198 PolarHBondContact O-N 2.98Å; L196-V199 WeakPolarHBondContact O-CB 3.27Å; L196-V199 PolarHBondContact O-N 3.16Å; L196-V199 VanDerWaalsContact O-N 3.15Å; L196-L200 HydrophobicContact CD1-CD1 4.27Å; L196-L200 HydrophobicContact CD1-CG 4.2Å; L196-L200 HydrophobicContact CG-CD1 4.16Å; L196-L200 WeakPolarHBondContact O-CG 3.46Å; L196-L200 PolarHBondContact O-N 3.43Å
197	L	98.2	Very high	94.9	Very high	92 Å²	92	46 Å²	46	48%	0.482	25%	0.253	S	S	.	.	H	α-helix	trans	-62.1	-40.7	175.5	-67.7	176	0	0	0	112	A193 F194 S195 V199 L200 N201	A193-L197 WeakPolarHBondContact O-CG 3.47Å; A193-L197 PolarHBondContact O-N 2.95Å; F194-L197 WeakPolarHBondContact O-CB 3.46Å; F194-L197 PolarHBondContact O-N 3.46Å; F194-L197 VanDerWaalsContact O-N 3.15Å; S195-L197 PolarHBondContact O-N 3.24Å; L197-V199 VanDerWaalsContact C-N 3.28Å; L197-V199 PolarHBondContact O-N 3.47Å; L197-L200 PolarHBondContact O-N 2.98Å; L197-N201 WeakPolarHBondContact O-CB 3.47Å; L197-N201 VanDerWaalsContact O-CG 3.3Å; L197-N201 PolarHBondContact O-N 3.26Å; L197-N201 PolarHBondContact O-ND2 3.15Å
198	L	98	Very high	93.8	Very high	22 Å²	22	46.6 Å²	46.6	12%	0.115	25%	0.253	C	S	.	.	H	α-helix	trans	-59	-42	173.3	-67.2	179.6	0	0	0	111.2	V34 I37 I38 L41 F194 S195 L196 N201 F202	V34-L198 HydrophobicContact CG1-CB 4.41Å; I37-L198 HydrophobicContact CG2-CD1 4.05Å; I38-L198 HydrophobicContact CD1-CB 4.14Å; I38-L198 HydrophobicContact CG1-CB 4.01Å; I38-L198 HydrophobicContact CG1-CD1 4.22Å; L41-L198 HydrophobicContact CD1-CD1 3.87Å; F194-L198 HydrophobicContact CD1-CD1 4.24Å; F194-L198 HydrophobicContact CD1-CG 4.43Å; F194-L198 HydrophobicContact CE1-CD1 3.78Å; F194-L198 HydrophobicContact CE1-CD2 4.3Å; F194-L198 HydrophobicContact CE1-CG 4.05Å; F194-L198 HydrophobicContact CZ-CD1 4.37Å; F194-L198 HydrophobicContact CZ-CD2 4.06Å; F194-L198 HydrophobicContact CZ-CG 4.24Å; F194-L198 PolarHBondContact O-N 2.96Å; S195-L198 WeakPolarHBondContact O-CB 3.24Å; S195-L198 PolarHBondContact O-N 3.16Å; L196-L198 VanDerWaalsContact C-N 3.34Å; L196-L198 PolarHBondContact O-N 2.98Å; L198-N201 PolarHBondContact O-N 3.09Å; L198-F202 HydrophobicContact CD2-CD2 4.01Å; L198-F202 HydrophobicContact CD2-CE2 3.83Å; L198-F202 WeakPolarHBondContact O-CB 3.47Å; L198-F202 WeakPolarHBondContact O-CD2 3.33Å; L198-F202 PolarHBondContact O-N 3.43Å
199	V	97.4	Very high	91.9	Very high	0 Å²	0	50.3 Å²	50.3	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-60.8	-50.2	176.8	178.7	0	0	0	0	111.1	I38 R95 L98 S99 S195 L196 L197 N201 I203	I38-V199 HydrophobicContact CD1-CG2 3.73Å; I38-V199 HydrophobicContact CG1-CG2 4.47Å; I38-V199 HydrophobicContact CG2-CG2 4.46Å; R95-V199 HydrophobicContact CG-CG1 4.38Å; L98-V199 HydrophobicContact CB-CG1 4.05Å; L98-V199 HydrophobicContact CD2-CG1 4.05Å; L98-V199 HydrophobicContact CD2-CG2 3.69Å; L98-V199 HydrophobicContact CG-CB 4.49Å; L98-V199 HydrophobicContact CG-CG1 3.98Å; L98-V199 HydrophobicContact CG-CG2 3.6Å; S99-V199 VanDerWaalsContact OG-CG1 3.3Å; S99-V199 WeakPolarHBondContact OG-CG1 3.31Å; S195-V199 WeakPolarHBondContact O-CG2 3.44Å; S195-V199 PolarHBondContact O-N 3.38Å; L196-V199 WeakPolarHBondContact O-CB 3.27Å; L196-V199 PolarHBondContact O-N 3.16Å; L196-V199 VanDerWaalsContact O-N 3.15Å; L197-V199 VanDerWaalsContact C-N 3.28Å; L197-V199 PolarHBondContact O-N 3.47Å; V199-N201 VanDerWaalsContact C-N 3.29Å; V199-N201 PolarHBondContact O-N 3.45Å; V199-I203 HydrophobicContact CB-CG1 4.41Å; V199-I203 HydrophobicContact CG1-CB 4.31Å; V199-I203 HydrophobicContact CG1-CG1 4.11Å; V199-I203 VanDerWaalsContact O-CB 3.32Å; V199-I203 WeakPolarHBondContact O-CB 3.38Å; V199-I203 PolarHBondContact O-N 3.34Å; V199-I203 VanDerWaalsContact O-N 3.08Å
200	L	96.5	Very high	89.5	Confident	69 Å²	69	57.8 Å²	57.8	36%	0.361	31%	0.313	S	S	.	.	H	α-helix	trans	-65.3	-32.8	-176.2	-66.6	175	0	0	0	112.7	R95 S99 L196 L197	R95-L200 VanDerWaalsContact CZ-O 3.22Å; R95-L200 PolarHBondContact NH1-O 3.41Å; R95-L200 PolarHBondContact NH2-O 3.04Å; S99-L200 WeakPolarHBondContact OG-CD2 3.4Å; L196-L200 HydrophobicContact CD1-CD1 4.27Å; L196-L200 HydrophobicContact CD1-CG 4.2Å; L196-L200 HydrophobicContact CG-CD1 4.16Å; L196-L200 WeakPolarHBondContact O-CG 3.46Å; L196-L200 PolarHBondContact O-N 3.43Å; L197-L200 PolarHBondContact O-N 2.98Å
201	N	96.4	Very high	86.9	Confident	120 Å²	120	58.1 Å²	58.1	64%	0.642	32%	0.316	S	S	*	.	H	α-helix	trans	-88.4	-36.3	-175.9	-68.7	-21.1	0	0	0	113.3	L197 L198 V199	L197-N201 WeakPolarHBondContact O-CB 3.47Å; L197-N201 VanDerWaalsContact O-CG 3.3Å; L197-N201 PolarHBondContact O-N 3.26Å; L197-N201 PolarHBondContact O-ND2 3.15Å; L198-N201 PolarHBondContact O-N 3.09Å; V199-N201 VanDerWaalsContact C-N 3.29Å; V199-N201 PolarHBondContact O-N 3.45Å
202	F	95.8	Very high	84.6	Confident	76 Å²	76	60 Å²	60	33%	0.333	33%	0.327	S	S	.	.	H	α-helix	trans	-110.3	-26	-169.7	-66.1	-77.6	0	0	0	114.7	V34 L198	V34-F202 HydrophobicContact CB-CB 4.24Å; V34-F202 HydrophobicContact CG1-CB 3.75Å; V34-F202 HydrophobicContact CG1-CD2 4.26Å; V34-F202 HydrophobicContact CG1-CG 4.15Å; V34-F202 HydrophobicContact CG2-CB 4.09Å; V34-F202 HydrophobicContact CG2-CD1 4.24Å; V34-F202 HydrophobicContact CG2-CG 4.03Å; L198-F202 HydrophobicContact CD2-CD2 4.01Å; L198-F202 HydrophobicContact CD2-CE2 3.83Å; L198-F202 WeakPolarHBondContact O-CB 3.47Å; L198-F202 WeakPolarHBondContact O-CD2 3.33Å; L198-F202 PolarHBondContact O-N 3.43Å
203	I	94.4	Very high	82.3	Confident	1 Å²	1	66.4 Å²	66.4	1%	0.005	35%	0.351	C	S	.	.	S	Bend	trans	-84.6	124.1	-178.2	-52	-58.5	0	0	0	109.3	V31 V35 I38 R95 L98 V140 V199 T207	V31-I203 HydrophobicContact CG1-CD1 3.76Å; V35-I203 HydrophobicContact CG2-CD1 3.63Å; I38-I203 HydrophobicContact CD1-CD1 4.28Å; I38-I203 HydrophobicContact CD1-CG1 4.37Å; R95-I203 HydrophobicContact CB-CG2 3.93Å; R95-I203 VanDerWaalsContact CD-O 3.28Å; R95-I203 WeakPolarHBondContact CD-O 3.31Å; R95-I203 HydrophobicContact CG-CB 4.3Å; R95-I203 HydrophobicContact CG-CG2 4.19Å; R95-I203 PolarHBondContact NH1-O 3.06Å; L98-I203 HydrophobicContact CD2-CG1 4.22Å; V140-I203 HydrophobicContact CG2-CG2 4.3Å; V199-I203 HydrophobicContact CB-CG1 4.41Å; V199-I203 HydrophobicContact CG1-CB 4.31Å; V199-I203 HydrophobicContact CG1-CG1 4.11Å; V199-I203 VanDerWaalsContact O-CB 3.32Å; V199-I203 WeakPolarHBondContact O-CB 3.38Å; V199-I203 PolarHBondContact O-N 3.34Å; V199-I203 VanDerWaalsContact O-N 3.08Å; I203-T207 HydrophobicContact CG2-CG2 4.41Å
204	P	90.7	Very high	79.4	Confident	42 Å²	42	68.9 Å²	68.9	27%	0.273	37%	0.366	S	S	.	.			trans	-68.7	151.6	-178.5	28.3	-34.1	0	0	0	111.7	R95 S206 T207	R95-P204 WeakPolarHBondContact CB-O 3.32Å; P204-S206 VanDerWaalsContact C-N 3.25Å; P204-S206 PolarHBondContact O-N 2.98Å; P204-T207 HydrophobicContact CG-CG2 4.13Å
205	K	86.5	Confident	76.8	Confident	179 Å²	179	67.8 Å²	67.8	78%	0.778	37%	0.369	S	S	*	.	S	Bend	trans	-63.1	-30.2	178.8	-69.1	-175.1	179.7	-179.4	0	113.2
206	S	82.4	Confident	74.3	Confident	53 Å²	53	69.6 Å²	69.6	37%	0.371	38%	0.38	S	S	.	.			trans	-119.1	117.4	171.4	-164.9	0	0	0	0	109.1	P204 K208 R213	P204-S206 VanDerWaalsContact C-N 3.25Å; P204-S206 PolarHBondContact O-N 2.98Å; S206-K208 PolarHBondContact OG-O 3.37Å; S206-K208 VanDerWaalsContact OG-O 3.14Å; S206-R213 PolarHBondContact OG-NH2 2.94Å
207	T	76.2	Confident	71.7	Confident	11 Å²	11	76.1 Å²	76.1	7%	0.067	41%	0.406	C	S	.	.			trans	-94.9	-28.7	171.3	49.7	0	0	0	0	111.3	A94 V140 D143 I203 P204	A94-T207 HydrophobicContact CB-CG2 4.17Å; A94-T207 WeakPolarHBondContact CB-OG1 3.29Å; V140-T207 HydrophobicContact CG1-CG2 4.15Å; V140-T207 HydrophobicContact CG2-CG2 4.41Å; D143-T207 WeakPolarHBondContact OD2-CB 3.47Å; D143-T207 PolarHBondContact OD2-OG1 2.96Å; I203-T207 HydrophobicContact CG2-CG2 4.41Å; P204-T207 HydrophobicContact CG-CG2 4.13Å
208	K	73.8	Confident	68.9	Low	48 Å²	48	76.9 Å²	76.9	21%	0.209	42%	0.419	C	S	.	.	S	Bend	trans	-75.4	133.5	176	-64.5	-176.1	180	179.7	0	111.3	S206	S206-K208 PolarHBondContact OG-O 3.37Å; S206-K208 VanDerWaalsContact OG-O 3.14Å
209	S	58.1	Low	66.4	Low	79 Å²	79	82.2 Å²	82.2	55%	0.552	44%	0.444	S	S	*	.			trans	-64.7	149.1	167.1	174.9	0	0	0	0	111.1	A211 S212 R213	S209-A211 PolarHBondContact O-N 3.33Å; S209-S212 WeakPolarHBondContact O-CB 3.45Å; S209-S212 PolarHBondContact O-N 3.22Å; S209-R213 PolarHBondContact O-N 3.38Å
210	E	47.2	Very low	63.7	Low	163 Å²	163	86.1 Å²	86.1	76%	0.762	47%	0.465	S	S	*	.	H	α-helix	trans	-56	-34.3	178	-73.9	-170.9	152.3	0	0	112.7	S212 R213	E210-S212 VanDerWaalsContact C-N 3.26Å; E210-S212 PolarHBondContact O-N 3.14Å; E210-R213 PolarHBondContact O-N 3.37Å
211	A	44.6	Very low	61	Low	72 Å²	72	91.2 Å²	91.2	60%	0.595	49%	0.487	S	S	*	.	H	α-helix	trans	-67.1	-22.2	176.3	0	0	0	0	0	113.9	S209 S214 T215	S209-A211 PolarHBondContact O-N 3.33Å; A211-S214 PolarHBondContact O-OG 3.36Å; A211-T215 PolarHBondContact O-OG1 2.82Å
212	S	50.3	Low	58.2	Low	48 Å²	48	92.3 Å²	92.3	34%	0.336	49%	0.492	S	S	.	.	H	α-helix	trans	-86	-23	177.9	-177.1	0	0	0	0	112.3	S209 E210 S214 T216	S209-S212 WeakPolarHBondContact O-CB 3.45Å; S209-S212 PolarHBondContact O-N 3.22Å; E210-S212 VanDerWaalsContact C-N 3.26Å; E210-S212 PolarHBondContact O-N 3.14Å; S212-S214 PolarHBondContact O-N 3.46Å; S212-T216 PolarHBondContact O-N 2.75Å; S212-T216 PolarHBondContact O-OG1 2.85Å
213	R	48	Very low	55.8	Low	135 Å²	135	96 Å²	96	51%	0.509	51%	0.508	S	S	.	.	H	α-helix	trans	-70.1	-28.3	177.6	-80.5	178.4	173.4	167.8	-1.8	113.4	S206 S209 E210	S206-R213 PolarHBondContact OG-NH2 2.94Å; S209-R213 PolarHBondContact O-N 3.38Å; E210-R213 PolarHBondContact O-N 3.37Å
214	S	37.7	Very low	53.5	Low	87 Å²	87	103.2 Å²	103.2	61%	0.608	54%	0.54	S	S	*	.	H	α-helix	trans	-77.6	-39.1	179.7	58.5	0	0	0	0	112.5	A211 S212	A211-S214 PolarHBondContact O-OG 3.36Å; S212-S214 PolarHBondContact O-N 3.46Å
215	T	44.3	Very low	51.5	Low	87 Å²	87	105.9 Å²	105.9	53%	0.534	56%	0.555	S	S	.	*	H	α-helix	trans	-70.9	-38.5	177.3	7	0	0	0	0	112.3	A211 K217 S218	A211-T215 PolarHBondContact O-OG1 2.82Å; T215-K217 VanDerWaalsContact C-N 3.33Å; T215-K217 PolarHBondContact O-N 3.49Å; T215-S218 PolarHBondContact O-N 3.37Å
216	T	46.3	Very low	50	Low	40 Å²	40	103 Å²	103	25%	0.245	54%	0.543	C	S	.	.	H	α-helix	trans	-66.4	-32.4	-178.4	-42.2	0	0	0	0	112.2	S212 S218 N220	S212-T216 PolarHBondContact O-N 2.75Å; S212-T216 PolarHBondContact O-OG1 2.85Å; T216-S218 VanDerWaalsContact C-N 3.27Å; T216-S218 PolarHBondContact O-N 3.36Å; T216-N220 HydrophobicContact CG2-CB 4.36Å; T216-N220 VanDerWaalsContact O-CB 3.24Å; T216-N220 WeakPolarHBondContact O-CB 3.5Å; T216-N220 PolarHBondContact O-N 3.26Å
217	K	42.8	Very low	49.2	Very low	174 Å²	174	101.8 Å²	101.8	76%	0.757	53%	0.534	S	S	*	.	H	α-helix	trans	-66.4	-24.9	-179.4	-80	-175.9	176.4	-177	0	114	T215	T215-K217 VanDerWaalsContact C-N 3.33Å; T215-K217 PolarHBondContact O-N 3.49Å
218	S	38.8	Very low	48.9	Very low	108 Å²	108	107.9 Å²	107.9	76%	0.755	57%	0.566	S	S	*	*	H	α-helix	trans	-89.1	-32.6	-178.8	-159.9	0	0	0	0	112.9	T215 T216	T215-S218 PolarHBondContact O-N 3.37Å; T216-S218 VanDerWaalsContact C-N 3.27Å; T216-S218 PolarHBondContact O-N 3.36Å
219	E	45.7	Very low	49.2	Very low	135 Å²	135	108 Å²	108	63%	0.631	58%	0.58	S	S	*	*	H	α-helix	trans	-90.3	-20.9	-178.1	-79.4	-169.8	146	0	0	114.8	Q221	E219-Q221 VanDerWaalsContact C-N 3.35Å; E219-Q221 PolarHBondContact O-N 3.36Å
220	N	41.9	Very low	50.3	Low	81 Å²	81	107.9 Å²	107.9	43%	0.433	57%	0.571	S	S	.	*	T	Hydrogen-bonded Turn	trans	-85.6	2	-167.7	-134	18.7	0	0	0	115.3	T216	T216-N220 HydrophobicContact CG2-CB 4.36Å; T216-N220 VanDerWaalsContact O-CB 3.24Å; T216-N220 WeakPolarHBondContact O-CB 3.5Å; T216-N220 PolarHBondContact O-N 3.26Å
221	Q	39.2	Very low	52.1	Low	177 Å²	177	102.1 Å²	102.1	83%	0.827	55%	0.545	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.5	-11.2	178.7	-72.1	-167.2	-6.3	0	0	113.7	E219	E219-Q221 VanDerWaalsContact C-N 3.35Å; E219-Q221 PolarHBondContact O-N 3.36Å
222	N	37.8	Very low	54.1	Low	142 Å²	142	102.4 Å²	102.4	76%	0.759	54%	0.539	S	S	*	.	S	Bend	trans	-135	2	-171.5	-117.4	-7.6	0	0	0	117.4	K224	N222-K224 VanDerWaalsContact C-N 3.32Å; N222-K224 PolarHBondContact O-N 2.66Å
223	K	45.8	Very low	56.1	Low	153 Å²	153	105.5 Å²	105.5	67%	0.665	54%	0.543	S	S	*	.			trans	-78.3	86.2	171.5	-79.1	-178.9	179.1	169	0	109.7	V225	K223-V225 PolarHBondContact O-N 3.38Å
224	K	46.2	Very low	58	Low	154 Å²	154	99.1 Å²	99.1	67%	0.67	52%	0.519	S	S	*	.			trans	-59.1	105.6	166.1	-72.3	-177.1	-179.2	179.4	0	107.7	N222 F226 S227	N222-K224 VanDerWaalsContact C-N 3.32Å; N222-K224 PolarHBondContact O-N 2.66Å; K224-F226 PolarHBondContact O-N 2.81Å; K224-S227 PolarHBondContact O-N 3.28Å
225	V	48.6	Very low	60.5	Low	97 Å²	97	97.1 Å²	97.1	59%	0.588	50%	0.501	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.3	108.9	169.6	176.1	0	0	0	0	106.7	P83 K223	P83-V225 HydrophobicContact CB-CG1 3.92Å; P83-V225 HydrophobicContact CG-CG1 4.28Å; K223-V225 PolarHBondContact O-N 3.38Å
226	F	54.6	Low	62.8	Low	120 Å²	120	101.1 Å²	101.1	53%	0.526	51%	0.511	S	S	.	.	T	Hydrogen-bonded Turn	trans	60.6	75.4	-169.9	-65.8	-91.7	0	0	0	115.2	K224 L228 I231	K224-F226 PolarHBondContact O-N 2.81Å; F226-L228 PolarHBondContact O-N 3.39Å; F226-I231 HydrophobicContact CD1-CD1 3.97Å
227	S	64.5	Low	64.9	Low	26 Å²	26	101.9 Å²	101.9	18%	0.182	51%	0.511	C	S	.	.			trans	-73.4	115.6	160.2	89.1	0	0	0	0	109.3	K224 G229 E230 I231	K224-S227 PolarHBondContact O-N 3.28Å; S227-G229 PolarHBondContact O-N 3.39Å; S227-G229 VanDerWaalsContact O-N 3.07Å; S227-E230 PolarHBondContact O-N 2.99Å; S227-E230 WeakPolarHBondContact OG-CB 3.32Å; S227-E230 WeakPolarHBondContact OG-CG 3.45Å; S227-E230 PolarHBondContact OG-N 2.87Å; S227-E230 PolarHBondContact OG-OE2 2.98Å; S227-I231 PolarHBondContact O-N 3.02Å
228	L	71.1	Confident	67.1	Low	140 Å²	140	99.2 Å²	99.2	73%	0.733	51%	0.511	S	S	*	.	H	α-helix	trans	-52.7	-27.9	171.8	-81.9	144.1	0	0	0	111.7	F226 T232	F226-L228 PolarHBondContact O-N 3.39Å; L228-T232 WeakPolarHBondContact O-CB 3.17Å; L228-T232 VanDerWaalsContact O-CG2 3.31Å; L228-T232 WeakPolarHBondContact O-CG2 3.23Å; L228-T232 PolarHBondContact O-N 3.15Å; L228-T232 PolarHBondContact O-OG1 2.92Å
229	G	79.8	Confident	69.4	Low	49 Å²	49	95.4 Å²	95.4	51%	0.505	49%	0.489	S	S	.	.	H	α-helix	trans	-64.3	-42	172.9	0	0	0	0	0	114.1	S227 T232 R233	S227-G229 PolarHBondContact O-N 3.39Å; S227-G229 VanDerWaalsContact O-N 3.07Å; G229-T232 WeakPolarHBondContact CA-OG1 3.4Å; G229-T232 PolarHBondContact O-OG1 3.49Å; G229-R233 WeakPolarHBondContact O-CB 3.39Å; G229-R233 PolarHBondContact O-N 2.84Å
230	E	82.1	Confident	71.7	Confident	78 Å²	78	89 Å²	89	36%	0.364	46%	0.459	S	S	.	.	H	α-helix	trans	-70.8	-39.8	176.5	-76.5	163.1	153	0	0	111.7	S227 T232 R233 L234	S227-E230 PolarHBondContact O-N 2.99Å; S227-E230 WeakPolarHBondContact OG-CB 3.32Å; S227-E230 WeakPolarHBondContact OG-CG 3.45Å; S227-E230 PolarHBondContact OG-N 2.87Å; S227-E230 PolarHBondContact OG-OE2 2.98Å; E230-T232 VanDerWaalsContact C-N 3.35Å; E230-T232 PolarHBondContact O-N 3.41Å; E230-R233 WeakPolarHBondContact O-CB 3.43Å; E230-R233 PolarHBondContact O-N 3.46Å; E230-L234 VanDerWaalsContact O-CG 3.31Å; E230-L234 WeakPolarHBondContact O-CG 3.32Å; E230-L234 PolarHBondContact O-N 3.38Å
231	I	83.8	Confident	74.1	Confident	42 Å²	42	88 Å²	88	22%	0.215	46%	0.456	C	S	.	.	H	α-helix	trans	-60.4	-48.2	176.3	-58.4	170.6	0	0	0	110	F226 S227 R233 L234 M235 L368	F226-I231 HydrophobicContact CD1-CD1 3.97Å; S227-I231 PolarHBondContact O-N 3.02Å; I231-R233 VanDerWaalsContact C-N 3.32Å; I231-R233 PolarHBondContact O-N 2.94Å; I231-L234 PolarHBondContact O-N 3.42Å; I231-M235 WeakPolarHBondContact O-CG 3.49Å; I231-M235 PolarHBondContact O-N 2.81Å; I231-L368 HydrophobicContact CG2-CD1 3.95Å; I231-L368 HydrophobicContact CG2-CD2 4.47Å
232	T	86.5	Confident	76.7	Confident	77 Å²	77	84.3 Å²	84.3	47%	0.472	44%	0.435	S	S	.	.	H	α-helix	trans	-65.5	-34.4	178.2	51.2	0	0	0	0	112.3	L228 G229 E230 K236	L228-T232 WeakPolarHBondContact O-CB 3.17Å; L228-T232 VanDerWaalsContact O-CG2 3.31Å; L228-T232 WeakPolarHBondContact O-CG2 3.23Å; L228-T232 PolarHBondContact O-N 3.15Å; L228-T232 PolarHBondContact O-OG1 2.92Å; G229-T232 WeakPolarHBondContact CA-OG1 3.4Å; G229-T232 PolarHBondContact O-OG1 3.49Å; E230-T232 VanDerWaalsContact C-N 3.35Å; E230-T232 PolarHBondContact O-N 3.41Å; T232-K236 WeakPolarHBondContact O-CG 3.27Å; T232-K236 PolarHBondContact O-N 3.15Å
233	R	91.9	Very high	79.4	Confident	114 Å²	114	78.4 Å²	78.4	43%	0.43	40%	0.403	S	S	.	.	H	α-helix	trans	-60.9	-49.1	170.9	-174.1	-174	78.8	-174.5	4.1	111.4	G229 E230 I231 M235 K236 F237 D361	G229-R233 WeakPolarHBondContact O-CB 3.39Å; G229-R233 PolarHBondContact O-N 2.84Å; E230-R233 WeakPolarHBondContact O-CB 3.43Å; E230-R233 PolarHBondContact O-N 3.46Å; I231-R233 VanDerWaalsContact C-N 3.32Å; I231-R233 PolarHBondContact O-N 2.94Å; R233-M235 VanDerWaalsContact C-N 3.35Å; R233-M235 PolarHBondContact O-N 2.79Å; R233-K236 WeakPolarHBondContact O-CB 3.29Å; R233-K236 PolarHBondContact O-N 3.48Å; R233-K236 VanDerWaalsContact O-N 3.16Å; R233-F237 HydrophobicContact CG-CE2 4.45Å; R233-F237 WeakPolarHBondContact O-CD2 3.35Å; R233-D361 IonicContact CZ-OD2 3.59Å; R233-D361 IonicContact NE-OD2 3.8Å; R233-D361 IonicContact NH2-OD1 2.9Å; R233-D361 PolarHBondContact NH2-OD1 2.98Å; R233-D361 IonicContact NH2-OD2 2.72Å; R233-D361 PolarHBondContact NH2-OD2 3.3Å
234	L	88.7	Confident	81.7	Confident	1 Å²	1	71.9 Å²	71.9	1%	0.005	37%	0.374	C	S	.	.	H	α-helix	trans	-61.5	-42.8	-179.3	-69.7	177	0	0	0	112.1	E230 I231 K236 F237 V240 V357 D361 T364	E230-L234 VanDerWaalsContact O-CG 3.31Å; E230-L234 WeakPolarHBondContact O-CG 3.32Å; E230-L234 PolarHBondContact O-N 3.38Å; I231-L234 PolarHBondContact O-N 3.42Å; L234-K236 PolarHBondContact O-N 3.21Å; L234-F237 HydrophobicContact CD2-CD2 4.43Å; L234-F237 HydrophobicContact CD2-CE2 4.19Å; L234-F237 PolarHBondContact O-N 2.6Å; L234-F237 VanDerWaalsContact O-N 3.11Å; L234-V240 WeakPolarHBondContact O-CG1 3.45Å; L234-V357 HydrophobicContact CD2-CG1 4.13Å; L234-D361 HydrophobicContact CD2-CB 3.74Å; L234-D361 WeakPolarHBondContact CD2-OD2 3.39Å; L234-T364 HydrophobicContact CD1-CG2 3.52Å
235	M	91.2	Very high	84	Confident	45 Å²	45	68.5 Å²	68.5	22%	0.222	36%	0.363	C	S	.	.	H	α-helix	trans	-62	-27	178.3	-70.5	-60.5	-69.8	0	0	113	I231 R233 F237 V240 T241 F244 L368	I231-M235 WeakPolarHBondContact O-CG 3.49Å; I231-M235 PolarHBondContact O-N 2.81Å; R233-M235 VanDerWaalsContact C-N 3.35Å; R233-M235 PolarHBondContact O-N 2.79Å; M235-F237 VanDerWaalsContact C-N 3.32Å; M235-F237 PolarHBondContact O-N 2.9Å; M235-V240 HydrophobicContact SD-CG1 4.26Å; M235-T241 HydrophobicContact CE-CG2 4.38Å; M235-T241 PolarHBondContact O-OG1 3.23Å; M235-F244 HydrophobicContact CE-CB 4.34Å; M235-F244 HydrophobicContact CE-CD1 3.55Å; M235-F244 HydrophobicContact CE-CE1 4.18Å; M235-F244 HydrophobicContact CE-CG 4.19Å; M235-F244 HydrophobicContact SD-CB 4.41Å; M235-F244 HydrophobicContact SD-CD1 3.75Å; M235-F244 HydrophobicContact SD-CE1 4.14Å; M235-F244 HydrophobicContact SD-CG 4.03Å; M235-L368 HydrophobicContact SD-CD2 3.94Å
236	K	91.6	Very high	86.2	Confident	171 Å²	171	64.3 Å²	64.3	74%	0.743	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.5	-11.2	178.1	-71.7	174.4	-178	-175.7	0	114.2	T232 R233 L234	T232-K236 WeakPolarHBondContact O-CG 3.27Å; T232-K236 PolarHBondContact O-N 3.15Å; R233-K236 WeakPolarHBondContact O-CB 3.29Å; R233-K236 PolarHBondContact O-N 3.48Å; R233-K236 VanDerWaalsContact O-N 3.16Å; L234-K236 PolarHBondContact O-N 3.21Å
237	F	90.5	Very high	88.1	Confident	55 Å²	55	58.9 Å²	58.9	24%	0.241	31%	0.313	C	S	.	.	S	Bend	trans	-62.5	134.5	176.6	-84.5	-95.1	0	0	0	111	R233 L234 M235 G239 V240 I356 P358	R233-F237 HydrophobicContact CG-CE2 4.45Å; R233-F237 WeakPolarHBondContact O-CD2 3.35Å; L234-F237 HydrophobicContact CD2-CD2 4.43Å; L234-F237 HydrophobicContact CD2-CE2 4.19Å; L234-F237 PolarHBondContact O-N 2.6Å; L234-F237 VanDerWaalsContact O-N 3.11Å; M235-F237 VanDerWaalsContact C-N 3.32Å; M235-F237 PolarHBondContact O-N 2.9Å; F237-G239 PolarHBondContact O-N 2.97Å; F237-V240 HydrophobicContact CB-CB 4.22Å; F237-V240 HydrophobicContact CB-CG2 3.53Å; F237-V240 PolarHBondContact O-N 3.46Å; F237-I356 HydrophobicContact CB-CG2 4.41Å; F237-P358 HydrophobicContact CE1-CG 3.88Å; F237-P358 HydrophobicContact CZ-CG 3.85Å
238	P	88.6	Confident	89.5	Confident	119 Å²	119	60.2 Å²	60.2	77%	0.773	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.5	115.2	-178.8	-25.3	33.6	0	0	0	111.9	I356	P238-I356 WeakPolarHBondContact O-CG2 3.29Å
239	G	88	Confident	90.7	Very high	28 Å²	28	57.6 Å²	57.6	29%	0.289	30%	0.304	S	S	.	.	T	Hydrogen-bonded Turn	trans	98.3	-21.6	178.8	0	0	0	0	0	115.6	F237 R242 I243	F237-G239 PolarHBondContact O-N 2.97Å; G239-R242 PolarHBondContact O-N 3.03Å; G239-I243 PolarHBondContact O-N 2.9Å
240	V	92.9	Very high	91.4	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-60.6	-56.7	179.2	171.4	0	0	0	0	110.9	L234 M235 F237 R242 I243 F244 L353 I356 V357 M365	L234-V240 WeakPolarHBondContact O-CG1 3.45Å; M235-V240 HydrophobicContact SD-CG1 4.26Å; F237-V240 HydrophobicContact CB-CB 4.22Å; F237-V240 HydrophobicContact CB-CG2 3.53Å; F237-V240 PolarHBondContact O-N 3.46Å; V240-R242 PolarHBondContact O-N 3.15Å; V240-I243 PolarHBondContact O-N 3.02Å; V240-I243 VanDerWaalsContact O-N 3.16Å; V240-F244 WeakPolarHBondContact O-CB 3.44Å; V240-F244 PolarHBondContact O-N 3.34Å; V240-L353 HydrophobicContact CB-CD2 4.45Å; V240-L353 HydrophobicContact CG1-CD2 3.97Å; V240-I356 HydrophobicContact CG2-CB 4.04Å; V240-I356 HydrophobicContact CG2-CG2 3.49Å; V240-I356 VanDerWaalsContact CG2-CG2 3.49Å; V240-V357 HydrophobicContact CG2-CG1 3.92Å; V240-M365 HydrophobicContact CG1-CE 4.48Å; V240-M365 HydrophobicContact CG1-SD 4.1Å
241	T	93.2	Very high	91.9	Very high	59 Å²	59	52.3 Å²	52.3	36%	0.362	27%	0.27	S	S	.	.	H	α-helix	trans	-51.3	-38.4	-179.9	-73.3	0	0	0	0	112	M235 L245	M235-T241 HydrophobicContact CE-CG2 4.38Å; M235-T241 PolarHBondContact O-OG1 3.23Å; T241-L245 HydrophobicContact CG2-CD1 3.82Å; T241-L245 HydrophobicContact CG2-CG 4.24Å; T241-L245 VanDerWaalsContact O-CB 3.32Å; T241-L245 WeakPolarHBondContact O-CB 3.43Å; T241-L245 WeakPolarHBondContact O-CG 3.36Å; T241-L245 PolarHBondContact O-N 3.06Å
242	R	93.3	Very high	92.4	Very high	101 Å²	101	52.8 Å²	52.8	38%	0.381	27%	0.273	S	S	.	.	H	α-helix	trans	-67.4	-53	-179.3	-173	-173.9	-67.2	132.2	-8.9	112.4	G239 V240 F244 L245 I246 R414	G239-R242 PolarHBondContact O-N 3.03Å; V240-R242 PolarHBondContact O-N 3.15Å; R242-F244 PolarHBondContact O-N 3.39Å; R242-L245 PolarHBondContact O-N 3.36Å; R242-I246 HydrophobicContact CG-CD1 4.25Å; R242-I246 WeakPolarHBondContact O-CG1 3.33Å; R242-I246 PolarHBondContact O-N 3.43Å; R242-R414 VanDerWaalsContact CZ-NH1 3.34Å
243	I	94.2	Very high	92.7	Very high	17 Å²	17	49.3 Å²	49.3	9%	0.087	25%	0.251	C	S	.	.	H	α-helix	trans	-66	-35.4	-179.8	-58.3	-56.7	0	0	0	110.2	G239 V240 I246 K247 M352 L353 I356	G239-I243 PolarHBondContact O-N 2.9Å; V240-I243 PolarHBondContact O-N 3.02Å; V240-I243 VanDerWaalsContact O-N 3.16Å; I243-I246 HydrophobicContact CD1-CD1 4.2Å; I243-I246 PolarHBondContact O-N 2.88Å; I243-K247 PolarHBondContact O-N 3.21Å; I243-M352 HydrophobicContact CD1-CE 3.53Å; I243-M352 HydrophobicContact CD1-SD 4.45Å; I243-M352 HydrophobicContact CG1-CE 4.18Å; I243-M352 HydrophobicContact CG2-CB 4.18Å; I243-L353 HydrophobicContact CB-CD2 3.86Å; I243-L353 HydrophobicContact CB-CG 4.14Å; I243-L353 HydrophobicContact CG2-CD1 4.14Å; I243-L353 HydrophobicContact CG2-CD2 4.02Å; I243-L353 HydrophobicContact CG2-CG 3.71Å; I243-I356 HydrophobicContact CG1-CD1 4.19Å
244	F	94	Very high	92.7	Very high	16 Å²	16	44 Å²	44	7%	0.07	23%	0.232	C	C	.	.	H	α-helix	trans	-64.9	-43.6	176.6	-165.2	-104.3	0	0	0	112.5	M235 V240 R242 K247 I248 L353 M365 L368 V372	M235-F244 HydrophobicContact CE-CB 4.34Å; M235-F244 HydrophobicContact CE-CD1 3.55Å; M235-F244 HydrophobicContact CE-CE1 4.18Å; M235-F244 HydrophobicContact CE-CG 4.19Å; M235-F244 HydrophobicContact SD-CB 4.41Å; M235-F244 HydrophobicContact SD-CD1 3.75Å; M235-F244 HydrophobicContact SD-CE1 4.14Å; M235-F244 HydrophobicContact SD-CG 4.03Å; V240-F244 WeakPolarHBondContact O-CB 3.44Å; V240-F244 PolarHBondContact O-N 3.34Å; R242-F244 PolarHBondContact O-N 3.39Å; F244-K247 WeakPolarHBondContact O-CB 3.4Å; F244-K247 PolarHBondContact O-N 2.92Å; F244-I248 HydrophobicContact CD1-CD1 3.79Å; F244-I248 HydrophobicContact CE1-CD1 3.41Å; F244-I248 VanDerWaalsContact CE1-CD1 3.41Å; F244-I248 HydrophobicContact CE1-CG1 4.33Å; F244-I248 HydrophobicContact CZ-CD1 4.05Å; F244-I248 PolarHBondContact O-N 2.83Å; F244-L353 HydrophobicContact CB-CD2 4.25Å; F244-L353 HydrophobicContact CD2-CD1 4.2Å; F244-M365 HydrophobicContact CD2-CE 3.98Å; F244-M365 HydrophobicContact CE2-CE 4.34Å; F244-L368 HydrophobicContact CD2-CD2 4.26Å; F244-L368 HydrophobicContact CD2-CG 4.48Å; F244-L368 HydrophobicContact CE1-CD2 4.45Å; F244-L368 HydrophobicContact CE2-CD1 4.43Å; F244-L368 HydrophobicContact CE2-CD2 3.76Å; F244-L368 HydrophobicContact CE2-CG 3.55Å; F244-L368 HydrophobicContact CZ-CD1 3.96Å; F244-L368 HydrophobicContact CZ-CD2 3.86Å; F244-L368 HydrophobicContact CZ-CG 3.58Å; F244-V372 HydrophobicContact CE1-CG2 4.42Å; F244-V372 HydrophobicContact CE2-CG2 3.67Å; F244-V372 HydrophobicContact CZ-CG2 3.49Å; F244-V372 VanDerWaalsContact CZ-CG2 3.49Å
245	L	94.6	Very high	92.9	Very high	83 Å²	83	44.2 Å²	44.2	44%	0.435	24%	0.235	S	C	.	.	H	α-helix	trans	-63.2	-40.1	173.5	-75.6	173.8	0	0	0	112	T241 R242 K247 I248 I249	T241-L245 HydrophobicContact CG2-CD1 3.82Å; T241-L245 HydrophobicContact CG2-CG 4.24Å; T241-L245 VanDerWaalsContact O-CB 3.32Å; T241-L245 WeakPolarHBondContact O-CB 3.43Å; T241-L245 WeakPolarHBondContact O-CG 3.36Å; T241-L245 PolarHBondContact O-N 3.06Å; R242-L245 PolarHBondContact O-N 3.36Å; L245-K247 VanDerWaalsContact C-N 3.31Å; L245-K247 PolarHBondContact O-N 3.03Å; L245-I248 PolarHBondContact O-N 3.45Å; L245-I249 HydrophobicContact CB-CD1 4.45Å; L245-I249 WeakPolarHBondContact O-CB 3.45Å; L245-I249 VanDerWaalsContact O-CG1 3.29Å; L245-I249 WeakPolarHBondContact O-CG1 3.33Å; L245-I249 PolarHBondContact O-N 2.87Å
246	I	95.1	Very high	93	Very high	10 Å²	10	42.4 Å²	42.4	5%	0.051	23%	0.226	C	C	.	.	H	α-helix	trans	-59.3	-45.7	172.7	-68.7	159.8	0	0	0	110.1	R242 I243 I248 I249 A250 I312 F345 V407 L411	R242-I246 HydrophobicContact CG-CD1 4.25Å; R242-I246 WeakPolarHBondContact O-CG1 3.33Å; R242-I246 PolarHBondContact O-N 3.43Å; I243-I246 HydrophobicContact CD1-CD1 4.2Å; I243-I246 PolarHBondContact O-N 2.88Å; I246-I248 VanDerWaalsContact C-N 3.32Å; I246-I248 PolarHBondContact O-N 3.04Å; I246-I249 PolarHBondContact O-N 2.82Å; I246-A250 VanDerWaalsContact O-CB 3.26Å; I246-A250 WeakPolarHBondContact O-CB 3.42Å; I246-A250 PolarHBondContact O-N 3.38Å; I246-I312 HydrophobicContact CG2-CD1 4.06Å; I246-F345 HydrophobicContact CG2-CE2 4.27Å; I246-V407 HydrophobicContact CG2-CG1 4.23Å; I246-L411 HydrophobicContact CD1-CD2 3.85Å
247	K	94.8	Very high	93	Very high	5 Å²	5	34.3 Å²	34.3	2%	0.022	19%	0.191	C	C	.	.	H	α-helix	trans	-56.6	-45.4	178.3	-167.8	-177.3	-179.5	88	0	111.9	I243 F244 L245 G251 F345 T349 D350 L353	I243-K247 PolarHBondContact O-N 3.21Å; F244-K247 WeakPolarHBondContact O-CB 3.4Å; F244-K247 PolarHBondContact O-N 2.92Å; L245-K247 VanDerWaalsContact C-N 3.31Å; L245-K247 PolarHBondContact O-N 3.03Å; K247-G251 WeakPolarHBondContact O-CA 3.19Å; K247-G251 PolarHBondContact O-N 3.5Å; K247-G251 VanDerWaalsContact O-N 3.15Å; K247-F345 HydrophobicContact CG-CE1 4.35Å; K247-T349 HydrophobicContact CB-CG2 4.32Å; K247-T349 HydrophobicContact CG-CG2 4.43Å; K247-T349 PolarHBondContact NZ-OG1 3.29Å; K247-D350 WeakPolarHBondContact CE-OD1 3.21Å; K247-D350 IonicContact NZ-OD1 3.91Å; K247-D350 PolarHBondContact NZ-OD1 2.89Å; K247-D350 IonicContact NZ-OD2 2.66Å; K247-L353 HydrophobicContact CD-CD1 4.28Å
248	I	94.4	Very high	93.1	Very high	55 Å²	55	36 Å²	36	28%	0.282	20%	0.199	S	C	.	.	H	α-helix	trans	-69.7	-55.1	179	-67.5	173.4	0	0	0	110.9	F244 L245 I246 L252 V372	F244-I248 HydrophobicContact CD1-CD1 3.79Å; F244-I248 HydrophobicContact CE1-CD1 3.41Å; F244-I248 VanDerWaalsContact CE1-CD1 3.41Å; F244-I248 HydrophobicContact CE1-CG1 4.33Å; F244-I248 HydrophobicContact CZ-CD1 4.05Å; F244-I248 PolarHBondContact O-N 2.83Å; L245-I248 PolarHBondContact O-N 3.45Å; I246-I248 VanDerWaalsContact C-N 3.32Å; I246-I248 PolarHBondContact O-N 3.04Å; I248-L252 WeakPolarHBondContact O-CB 3.36Å; I248-L252 PolarHBondContact O-N 3.14Å; I248-V372 HydrophobicContact CD1-CG2 4.33Å; I248-V372 HydrophobicContact CG1-CG1 3.93Å; I248-V372 HydrophobicContact CG1-CG2 3.97Å
249	I	95.6	Very high	93.1	Very high	85 Å²	85	32 Å²	32	44%	0.436	17%	0.172	S	C	.	.	H	α-helix	trans	-65.8	-50.6	-171.3	-66.8	169.1	0	0	0	110.7	L245 I246 P253 V403 V407	L245-I249 HydrophobicContact CB-CD1 4.45Å; L245-I249 WeakPolarHBondContact O-CB 3.45Å; L245-I249 VanDerWaalsContact O-CG1 3.29Å; L245-I249 WeakPolarHBondContact O-CG1 3.33Å; L245-I249 PolarHBondContact O-N 2.87Å; I246-I249 PolarHBondContact O-N 2.82Å; I249-P253 VanDerWaalsContact O-CD 3.27Å; I249-P253 WeakPolarHBondContact O-CD 3.23Å; I249-V403 HydrophobicContact CG2-CG1 3.54Å; I249-V403 WeakPolarHBondContact O-CG1 3.38Å; I249-V407 HydrophobicContact CG2-CG2 3.99Å
250	A	94.9	Very high	93.3	Very high	1 Å²	1	30.7 Å²	30.7	1%	0.008	16%	0.159	C	C	.	.	H	α-helix	trans	-74.8	-32.1	-178.1	0	0	0	0	0	112.7	I246 F345 N404 V407	I246-A250 VanDerWaalsContact O-CB 3.26Å; I246-A250 WeakPolarHBondContact O-CB 3.42Å; I246-A250 PolarHBondContact O-N 3.38Å; A250-F345 HydrophobicContact CB-CE2 3.84Å; A250-F345 HydrophobicContact CB-CZ 3.78Å; A250-N404 WeakPolarHBondContact CB-OD1 3.45Å; A250-N404 PolarHBondContact O-ND2 2.88Å; A250-N404 PolarHBondContact O-OD1 2.93Å; A250-V407 HydrophobicContact CB-CG1 4.38Å; A250-V407 HydrophobicContact CB-CG2 4.49Å
251	G	93	Very high	93.1	Very high	14 Å²	14	30.8 Å²	30.8	14%	0.144	16%	0.159	C	C	.	.	H	α-helix	trans	-82.1	-25.8	-177.6	0	0	0	0	0	115.1	K247 G255	K247-G251 WeakPolarHBondContact O-CA 3.19Å; K247-G251 PolarHBondContact O-N 3.5Å; K247-G251 VanDerWaalsContact O-N 3.15Å; G251-G255 PolarHBondContact O-N 3.48Å
252	L	93.1	Very high	92.8	Very high	52 Å²	52	28.6 Å²	28.6	27%	0.272	15%	0.146	S	C	.	.	H	α-helix	trans	-62.8	-46.2	-174	-178.8	127	0	0	0	113.5	I248 G255 I256 V376	I248-L252 WeakPolarHBondContact O-CB 3.36Å; I248-L252 PolarHBondContact O-N 3.14Å; L252-G255 PolarHBondContact O-N 3.32Å; L252-I256 HydrophobicContact CD2-CD1 3.74Å; L252-I256 HydrophobicContact CG-CD1 4.15Å; L252-I256 WeakPolarHBondContact O-CG1 3.31Å; L252-I256 PolarHBondContact O-N 2.98Å; L252-V376 HydrophobicContact CD1-CG2 4.23Å
253	P	93.6	Very high	92.5	Very high	4 Å²	4	24.1 Å²	24.1	3%	0.026	13%	0.13	C	C	.	.	H	α-helix	trans	-59.3	-48.9	178.1	-24.9	34.8	0	0	0	113.5	I249 G255 I256 F257 I399 E400 V403	I249-P253 VanDerWaalsContact O-CD 3.27Å; I249-P253 WeakPolarHBondContact O-CD 3.23Å; P253-G255 PolarHBondContact O-N 3.38Å; P253-I256 WeakPolarHBondContact O-CB 3.25Å; P253-I256 PolarHBondContact O-N 3.09Å; P253-F257 PolarHBondContact O-N 2.9Å; P253-I399 HydrophobicContact CB-CG2 4.41Å; P253-I399 HydrophobicContact CG-CG2 4.26Å; P253-E400 VanDerWaalsContact CB-CA 3.47Å; P253-E400 HydrophobicContact CB-CB 3.62Å; P253-E400 HydrophobicContact CB-CG 4.01Å; P253-V403 HydrophobicContact CG-CB 4.12Å; P253-V403 HydrophobicContact CG-CG1 4.18Å; P253-V403 HydrophobicContact CG-CG2 4.33Å
254	S	92.3	Very high	92.4	Very high	2 Å²	2	23.3 Å²	23.3	1%	0.014	13%	0.126	C	C	.	.	H	α-helix	trans	-61	-36	177.7	-50.3	0	0	0	0	111.9	F257 Q258 T315 E400	S254-F257 PolarHBondContact O-N 2.89Å; S254-Q258 WeakPolarHBondContact O-CB 3.39Å; S254-Q258 PolarHBondContact O-N 3.07Å; S254-T315 WeakPolarHBondContact OG-CG2 3.38Å; S254-E400 WeakPolarHBondContact CA-OE2 3.47Å; S254-E400 WeakPolarHBondContact CB-OE1 3.08Å; S254-E400 VanDerWaalsContact OG-CD 3.3Å; S254-E400 PolarHBondContact OG-OE1 3.41Å
255	G	91.8	Very high	92.3	Very high	7 Å²	7	22.5 Å²	22.5	7%	0.072	12%	0.122	C	C	.	.	H	α-helix	trans	-68	-36.8	175	0	0	0	0	0	113.5	G251 L252 P253 Q258 V259	G251-G255 PolarHBondContact O-N 3.48Å; L252-G255 PolarHBondContact O-N 3.32Å; P253-G255 PolarHBondContact O-N 3.38Å; G255-Q258 WeakPolarHBondContact O-CB 3.43Å; G255-Q258 PolarHBondContact O-N 3.32Å; G255-V259 WeakPolarHBondContact O-CG1 3.35Å; G255-V259 WeakPolarHBondContact O-CG2 3.3Å; G255-V259 PolarHBondContact O-N 2.78Å
256	I	93.3	Very high	92.1	Very high	7 Å²	7	19.3 Å²	19.3	4%	0.036	11%	0.105	C	C	.	.	H	α-helix	trans	-62.5	-47	173.2	-70.7	167.1	0	0	0	110.3	L252 P253 Q258 V259 M260 I383 G384 I396	L252-I256 HydrophobicContact CD2-CD1 3.74Å; L252-I256 HydrophobicContact CG-CD1 4.15Å; L252-I256 WeakPolarHBondContact O-CG1 3.31Å; L252-I256 PolarHBondContact O-N 2.98Å; P253-I256 WeakPolarHBondContact O-CB 3.25Å; P253-I256 PolarHBondContact O-N 3.09Å; I256-Q258 VanDerWaalsContact C-N 3.3Å; I256-Q258 PolarHBondContact O-N 3.49Å; I256-V259 WeakPolarHBondContact O-CG2 3.5Å; I256-V259 PolarHBondContact O-N 2.94Å; I256-M260 HydrophobicContact CG2-CG 4.35Å; I256-M260 WeakPolarHBondContact O-CB 3.42Å; I256-M260 VanDerWaalsContact O-CG 3.27Å; I256-M260 WeakPolarHBondContact O-CG 3.28Å; I256-M260 PolarHBondContact O-N 2.84Å; I256-I383 HydrophobicContact CD1-CB 4.41Å; I256-I383 HydrophobicContact CD1-CG2 3.82Å; I256-G384 VanDerWaalsContact CG2-CA 3.47Å; I256-I396 HydrophobicContact CG2-CG2 4.33Å
257	F	92.8	Very high	91.8	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-59.8	-43.5	176.2	-170.3	-80.4	0	0	0	111.1	P253 S254 V259 M260 F261 I264 Q322 M325 W338 L393 I396	P253-F257 PolarHBondContact O-N 2.9Å; S254-F257 PolarHBondContact O-N 2.89Å; F257-V259 PolarHBondContact O-N 3.43Å; F257-M260 PolarHBondContact O-N 3.34Å; F257-F261 HydrophobicContact CE1-CD2 4.38Å; F257-F261 PolarHBondContact O-N 3.3Å; F257-I264 HydrophobicContact CD2-CD1 4.09Å; F257-I264 HydrophobicContact CE2-CD1 3.98Å; F257-I264 HydrophobicContact CZ-CD1 4.31Å; F257-Q322 HydrophobicContact CD2-CG 4.37Å; F257-Q322 HydrophobicContact CE2-CB 4.05Å; F257-Q322 HydrophobicContact CE2-CG 3.84Å; F257-Q322 HydrophobicContact CZ-CG 3.99Å; F257-M325 HydrophobicContact CE2-CE 4.33Å; F257-M325 HydrophobicContact CZ-CE 4.01Å; F257-W338 AromaticContact CD1-CH2 3.48Å; F257-W338 HydrophobicContact CD1-CH2 3.48Å; F257-W338 VanDerWaalsContact CD1-CH2 3.48Å; F257-W338 AromaticContact CD1-CZ2 3.67Å; F257-W338 HydrophobicContact CD1-CZ2 3.67Å; F257-W338 AromaticContact CD1-CZ3 3.96Å; F257-W338 HydrophobicContact CD1-CZ3 3.96Å; F257-W338 HydrophobicContact CE1-CE3 4.5Å; F257-W338 AromaticContact CE1-CH2 3.9Å; F257-W338 HydrophobicContact CE1-CH2 3.9Å; F257-W338 HydrophobicContact CE1-CZ2 4.43Å; F257-W338 AromaticContact CE1-CZ3 3.91Å; F257-W338 HydrophobicContact CE1-CZ3 3.91Å; F257-L393 HydrophobicContact CE2-CD1 4Å; F257-I396 HydrophobicContact CB-CG2 3.97Å; F257-I396 HydrophobicContact CD2-CG2 3.93Å; F257-I396 HydrophobicContact CG-CG2 4.45Å
258	Q	91.3	Very high	91.7	Very high	91 Å²	91	23.9 Å²	23.9	43%	0.425	13%	0.126	S	C	.	.	H	α-helix	trans	-57.4	-47.3	178.8	-166.7	-178.4	-2.2	0	0	112.8	S254 G255 I256 M260 F261 W338	S254-Q258 WeakPolarHBondContact O-CB 3.39Å; S254-Q258 PolarHBondContact O-N 3.07Å; G255-Q258 WeakPolarHBondContact O-CB 3.43Å; G255-Q258 PolarHBondContact O-N 3.32Å; I256-Q258 VanDerWaalsContact C-N 3.3Å; I256-Q258 PolarHBondContact O-N 3.49Å; Q258-M260 VanDerWaalsContact C-N 3.34Å; Q258-F261 WeakPolarHBondContact O-CB 3.46Å; Q258-F261 PolarHBondContact O-N 3.39Å; Q258-W338 HydrophobicContact CB-CH2 4.12Å; Q258-W338 HydrophobicContact CB-CZ2 3.79Å; Q258-W338 HydrophobicContact CG-CH2 4.3Å; Q258-W338 HydrophobicContact CG-CZ2 4.26Å
259	V	89.9	Confident	91.6	Very high	34 Å²	34	22.4 Å²	22.4	21%	0.206	12%	0.118	C	C	.	.	H	α-helix	trans	-77.1	-21.9	-177.9	-59.7	0	0	0	0	113.1	G255 I256 F257 P381	G255-V259 WeakPolarHBondContact O-CG1 3.35Å; G255-V259 WeakPolarHBondContact O-CG2 3.3Å; G255-V259 PolarHBondContact O-N 2.78Å; I256-V259 WeakPolarHBondContact O-CG2 3.5Å; I256-V259 PolarHBondContact O-N 2.94Å; F257-V259 PolarHBondContact O-N 3.43Å; V259-P381 HydrophobicContact CB-CG 4.15Å; V259-P381 HydrophobicContact CG2-CG 3.91Å
260	M	90.5	Very high	91.4	Very high	2 Å²	2	25.5 Å²	25.5	1%	0.01	13%	0.129	C	C	.	.	H	α-helix	trans	-87.1	-8.1	175.1	-67.5	-69.6	79.9	0	0	114.3	I256 F257 Q258 S262 I263 I264 P381 G384 G385	I256-M260 HydrophobicContact CG2-CG 4.35Å; I256-M260 WeakPolarHBondContact O-CB 3.42Å; I256-M260 VanDerWaalsContact O-CG 3.27Å; I256-M260 WeakPolarHBondContact O-CG 3.28Å; I256-M260 PolarHBondContact O-N 2.84Å; F257-M260 PolarHBondContact O-N 3.34Å; Q258-M260 VanDerWaalsContact C-N 3.34Å; M260-S262 VanDerWaalsContact C-N 3.34Å; M260-S262 PolarHBondContact O-N 2.85Å; M260-I263 HydrophobicContact CE-CD1 3.55Å; M260-I263 HydrophobicContact CE-CG1 4.41Å; M260-I263 WeakPolarHBondContact O-CB 3.45Å; M260-I263 PolarHBondContact O-N 3.33Å; M260-I263 HydrophobicContact SD-CD1 3.79Å; M260-I264 HydrophobicContact CB-CD1 3.92Å; M260-I264 HydrophobicContact CB-CG1 4.33Å; M260-I264 WeakPolarHBondContact O-CG1 3.19Å; M260-I264 PolarHBondContact O-N 3.29Å; M260-P381 HydrophobicContact CE-CB 3.58Å; M260-P381 HydrophobicContact CE-CG 4.4Å; M260-G384 VanDerWaalsContact SD-C 3.54Å; M260-G385 PolarHBondContact SD-N 3.31Å
261	F	90.4	Very high	91.4	Very high	1 Å²	1	26.2 Å²	26.2	0%	0.004	13%	0.132	C	C	.	.	H	α-helix	trans	-52.7	-46.3	-171.1	177.3	-104.5	0	0	0	113.7	F257 Q258 I263 I264 A265 L279 M280 F283 L331	F257-F261 HydrophobicContact CE1-CD2 4.38Å; F257-F261 PolarHBondContact O-N 3.3Å; Q258-F261 WeakPolarHBondContact O-CB 3.46Å; Q258-F261 PolarHBondContact O-N 3.39Å; F261-I263 VanDerWaalsContact C-N 3.25Å; F261-I263 PolarHBondContact O-N 3.08Å; F261-I264 PolarHBondContact O-N 3.17Å; F261-I264 VanDerWaalsContact O-N 3.12Å; F261-A265 HydrophobicContact CE1-CB 4.42Å; F261-A265 HydrophobicContact CZ-CB 4.25Å; F261-A265 WeakPolarHBondContact O-CB 3.47Å; F261-A265 PolarHBondContact O-N 3.47Å; F261-L279 HydrophobicContact CE1-CB 4.32Å; F261-L279 HydrophobicContact CZ-CB 3.97Å; F261-L279 HydrophobicContact CZ-CD1 4.06Å; F261-M280 HydrophobicContact CD1-CE 3.58Å; F261-M280 HydrophobicContact CD1-CG 4.44Å; F261-M280 HydrophobicContact CD1-SD 3.62Å; F261-M280 HydrophobicContact CE1-CE 4.17Å; F261-M280 HydrophobicContact CE1-CG 4.13Å; F261-M280 HydrophobicContact CE1-SD 3.83Å; F261-F283 AromaticContact CD1-CE2 3.89Å; F261-F283 HydrophobicContact CD1-CE2 3.89Å; F261-F283 HydrophobicContact CD1-CZ 4.23Å; F261-F283 AromaticContact CD2-CE2 3.9Å; F261-F283 HydrophobicContact CD2-CE2 3.9Å; F261-F283 AromaticContact CD2-CZ 3.78Å; F261-F283 HydrophobicContact CD2-CZ 3.78Å; F261-F283 AromaticContact CE1-CE2 3.97Å; F261-F283 HydrophobicContact CE1-CE2 3.97Å; F261-F283 AromaticContact CE1-CZ 3.91Å; F261-F283 HydrophobicContact CE1-CZ 3.91Å; F261-F283 HydrophobicContact CE2-CE1 4.34Å; F261-F283 HydrophobicContact CE2-CE2 4Å; F261-F283 AromaticContact CE2-CZ 3.44Å; F261-F283 HydrophobicContact CE2-CZ 3.44Å; F261-F283 VanDerWaalsContact CE2-CZ 3.44Å; F261-F283 AromaticContact CG-CE2 3.86Å; F261-F283 HydrophobicContact CG-CE2 3.86Å; F261-F283 HydrophobicContact CG-CZ 4.17Å; F261-F283 HydrophobicContact CZ-CE1 4.1Å; F261-F283 HydrophobicContact CZ-CE2 4.03Å; F261-F283 AromaticContact CZ-CZ 3.5Å; F261-F283 HydrophobicContact CZ-CZ 3.5Å; F261-L331 HydrophobicContact CE2-CD1 4.18Å; F261-L331 HydrophobicContact CE2-CD2 3.65Å; F261-L331 HydrophobicContact CZ-CD2 4.08Å
262	S	86	Confident	91.3	Very high	13 Å²	13	30.3 Å²	30.3	9%	0.091	15%	0.147	C	C	.	.	H	α-helix	trans	-62.2	-31.9	-179.8	-57.9	0	0	0	0	113.4	M260 M266 M280	M260-S262 VanDerWaalsContact C-N 3.34Å; M260-S262 PolarHBondContact O-N 2.85Å; S262-M266 WeakPolarHBondContact O-CB 3.48Å; S262-M266 PolarHBondContact O-N 3.38Å; S262-M280 WeakPolarHBondContact OG-CE 3.05Å
263	I	87.4	Confident	91.2	Very high	7 Å²	7	28.1 Å²	28.1	4%	0.036	14%	0.137	C	C	.	.	H	α-helix	trans	-72.9	-46	174.5	-53.3	178.7	0	0	0	109.4	T64 F67 M260 F261 A265 M266 D267	T64-I263 HydrophobicContact CG2-CD1 3.88Å; T64-I263 HydrophobicContact CG2-CG2 3.67Å; F67-I263 HydrophobicContact CB-CD1 4.26Å; F67-I263 HydrophobicContact CD1-CD1 3.47Å; F67-I263 VanDerWaalsContact CD1-CD1 3.47Å; F67-I263 HydrophobicContact CD1-CG1 3.63Å; F67-I263 HydrophobicContact CE1-CD1 4.23Å; F67-I263 HydrophobicContact CE1-CG1 4.01Å; F67-I263 HydrophobicContact CG-CD1 4.23Å; F67-I263 HydrophobicContact CG-CG1 4.4Å; M260-I263 HydrophobicContact CE-CD1 3.55Å; M260-I263 HydrophobicContact CE-CG1 4.41Å; M260-I263 WeakPolarHBondContact O-CB 3.45Å; M260-I263 PolarHBondContact O-N 3.33Å; M260-I263 HydrophobicContact SD-CD1 3.79Å; F261-I263 VanDerWaalsContact C-N 3.25Å; F261-I263 PolarHBondContact O-N 3.08Å; I263-A265 VanDerWaalsContact C-N 3.3Å; I263-A265 PolarHBondContact O-N 3.27Å; I263-M266 PolarHBondContact O-N 2.66Å; I263-M266 VanDerWaalsContact O-N 3.08Å; I263-D267 HydrophobicContact CG2-CB 4.35Å; I263-D267 VanDerWaalsContact CG2-OD2 3.27Å; I263-D267 WeakPolarHBondContact CG2-OD2 3.42Å; I263-D267 WeakPolarHBondContact O-CB 3.45Å; I263-D267 PolarHBondContact O-N 3.41Å
264	I	92.1	Very high	91.2	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-58	-45.2	178.4	-63.4	166.2	0	0	0	110.2	F257 M260 F261 M266 F268 F269 Y388 L393 I396	F257-I264 HydrophobicContact CD2-CD1 4.09Å; F257-I264 HydrophobicContact CE2-CD1 3.98Å; F257-I264 HydrophobicContact CZ-CD1 4.31Å; M260-I264 HydrophobicContact CB-CD1 3.92Å; M260-I264 HydrophobicContact CB-CG1 4.33Å; M260-I264 WeakPolarHBondContact O-CG1 3.19Å; M260-I264 PolarHBondContact O-N 3.29Å; F261-I264 PolarHBondContact O-N 3.17Å; F261-I264 VanDerWaalsContact O-N 3.12Å; I264-M266 VanDerWaalsContact C-N 3.29Å; I264-M266 PolarHBondContact O-N 3.32Å; I264-F268 HydrophobicContact CG2-CB 4.11Å; I264-F268 WeakPolarHBondContact O-CA 3.33Å; I264-F268 WeakPolarHBondContact O-CB 3.38Å; I264-F268 PolarHBondContact O-N 3.35Å; I264-F269 HydrophobicContact CG2-CD2 4.17Å; I264-F269 HydrophobicContact CG2-CE2 3.96Å; I264-F269 PolarHBondContact O-N 3.03Å; I264-Y388 HydrophobicContact CG1-CD2 4.24Å; I264-Y388 HydrophobicContact CG1-CE2 4.09Å; I264-L393 HydrophobicContact CD1-CD1 3.66Å; I264-L393 HydrophobicContact CG1-CD1 3.92Å; I264-L393 HydrophobicContact CG2-CD1 3.77Å; I264-L393 HydrophobicContact CG2-CD2 4.13Å; I264-I396 HydrophobicContact CD1-CD1 4.47Å
265	A	91.6	Very high	91.2	Very high	0 Å²	0	34 Å²	34	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-54.6	-44.1	175.2	0	0	0	0	0	112.3	F261 I263 F269 K270 L271 N276	F261-A265 HydrophobicContact CE1-CB 4.42Å; F261-A265 HydrophobicContact CZ-CB 4.25Å; F261-A265 WeakPolarHBondContact O-CB 3.47Å; F261-A265 PolarHBondContact O-N 3.47Å; I263-A265 VanDerWaalsContact C-N 3.3Å; I263-A265 PolarHBondContact O-N 3.27Å; A265-F269 CarbonylContact O-C 3.58Å; A265-F269 WeakPolarHBondContact O-CB 3.5Å; A265-K270 PolarHBondContact O-N 3.04Å; A265-L271 HydrophobicContact CB-CD1 4.17Å; A265-L271 VanDerWaalsContact O-CB 3.3Å; A265-L271 WeakPolarHBondContact O-CB 3.29Å; A265-L271 WeakPolarHBondContact O-CG 3.45Å; A265-L271 PolarHBondContact O-N 3.42Å; A265-N276 HydrophobicContact CB-CB 4.34Å; A265-N276 WeakPolarHBondContact CB-OD1 3.27Å
266	M	89.8	Confident	91.2	Very high	15 Å²	15	33.7 Å²	33.7	7%	0.074	16%	0.16	C	C	.	.	H	α-helix	trans	-84.4	-40.1	-174.7	-167.1	-168.9	-32	0	0	113.9	P54 Y55 K58 S262 I263 I264 K270	P54-M266 HydrophobicContact CB-CE 3.26Å; P54-M266 WeakPolarHBondContact O-CE 3.36Å; Y55-M266 HydrophobicContact CD1-CE 4.15Å; Y55-M266 HydrophobicContact CD1-CG 4.11Å; Y55-M266 HydrophobicContact CD1-SD 3.9Å; Y55-M266 HydrophobicContact CD2-CE 3.97Å; Y55-M266 HydrophobicContact CE1-CB 4.36Å; Y55-M266 HydrophobicContact CE1-CE 4.24Å; Y55-M266 HydrophobicContact CE1-CG 3.67Å; Y55-M266 HydrophobicContact CE1-SD 4.06Å; Y55-M266 HydrophobicContact CE2-CE 4.06Å; Y55-M266 HydrophobicContact CG-CE 4.01Å; Y55-M266 HydrophobicContact CG-SD 4.27Å; K58-M266 HydrophobicContact CB-SD 3.87Å; K58-M266 HydrophobicContact CD-CG 4.13Å; K58-M266 HydrophobicContact CD-SD 3.23Å; K58-M266 WeakPolarHBondContact CD-SD 3.32Å; K58-M266 HydrophobicContact CG-SD 4.21Å; S262-M266 WeakPolarHBondContact O-CB 3.48Å; S262-M266 PolarHBondContact O-N 3.38Å; I263-M266 PolarHBondContact O-N 2.66Å; I263-M266 VanDerWaalsContact O-N 3.08Å; I264-M266 VanDerWaalsContact C-N 3.29Å; I264-M266 PolarHBondContact O-N 3.32Å; M266-K270 VanDerWaalsContact O-CA 3.31Å; M266-K270 WeakPolarHBondContact O-CA 3.5Å
267	D	89.5	Confident	91.2	Very high	32 Å²	32	33.3 Å²	33.3	17%	0.171	16%	0.159	C	C	.	.	H	α-helix	trans	-92.2	-40.4	-172.9	-74.6	-16.3	0	0	0	112.3	K58 T64 I263 K270 Y388	K58-D267 IonicContact NZ-OD1 3.61Å; K58-D267 PolarHBondContact NZ-OD1 2.9Å; T64-D267 PolarHBondContact OG1-OD2 3.36Å; I263-D267 HydrophobicContact CG2-CB 4.35Å; I263-D267 VanDerWaalsContact CG2-OD2 3.27Å; I263-D267 WeakPolarHBondContact CG2-OD2 3.42Å; I263-D267 WeakPolarHBondContact O-CB 3.45Å; I263-D267 PolarHBondContact O-N 3.41Å; D267-K270 WeakPolarHBondContact O-CD 3.29Å; D267-K270 WeakPolarHBondContact O-CE 3.38Å; D267-K270 PolarHBondContact O-NZ 3Å; D267-Y388 HydrophobicContact CB-CE1 4.1Å; D267-Y388 WeakPolarHBondContact CB-OH 3.19Å
268	F	91.9	Very high	91.2	Very high	79 Å²	79	38.4 Å²	38.4	35%	0.346	18%	0.178	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84.5	-54.8	179.1	-174.2	-101.1	0	0	0	111.1	I264 K270 M325 Y388 L393	I264-F268 HydrophobicContact CG2-CB 4.11Å; I264-F268 WeakPolarHBondContact O-CA 3.33Å; I264-F268 WeakPolarHBondContact O-CB 3.38Å; I264-F268 PolarHBondContact O-N 3.35Å; F268-K270 VanDerWaalsContact C-N 3.34Å; F268-M325 WeakPolarHBondContact CE1-O 3.4Å; F268-M325 VanDerWaalsContact CZ-O 3.23Å; F268-M325 WeakPolarHBondContact CZ-O 3.38Å; F268-Y388 HydrophobicContact CB-CE2 4.45Å; F268-Y388 WeakPolarHBondContact CB-OH 3.44Å; F268-Y388 PolarHBondContact N-OH 3.42Å; F268-Y388 VanDerWaalsContact N-OH 3.15Å; F268-L393 HydrophobicContact CB-CD2 4.44Å; F268-L393 HydrophobicContact CD1-CD2 3.57Å; F268-L393 HydrophobicContact CD2-CB 4.14Å; F268-L393 HydrophobicContact CD2-CD2 3.83Å; F268-L393 HydrophobicContact CE1-CD2 3.62Å; F268-L393 HydrophobicContact CE2-CB 4.29Å; F268-L393 HydrophobicContact CE2-CD2 3.87Å; F268-L393 HydrophobicContact CG-CD2 3.68Å; F268-L393 HydrophobicContact CZ-CD2 3.77Å
269	F	92.5	Very high	91.2	Very high	25 Å²	25	34.7 Å²	34.7	11%	0.11	16%	0.162	C	C	.	.	S	Bend	trans	-85.1	-6.4	-176.1	-65.7	-66.4	0	0	0	114.2	I264 A265 L271 M325 T327 V328 L331	I264-F269 HydrophobicContact CG2-CD2 4.17Å; I264-F269 HydrophobicContact CG2-CE2 3.96Å; I264-F269 PolarHBondContact O-N 3.03Å; A265-F269 CarbonylContact O-C 3.58Å; A265-F269 WeakPolarHBondContact O-CB 3.5Å; F269-L271 HydrophobicContact CB-CD1 3.91Å; F269-L271 HydrophobicContact CB-CD2 4.23Å; F269-L271 HydrophobicContact CB-CG 3.61Å; F269-L271 PolarHBondContact O-N 3.21Å; F269-M325 HydrophobicContact CE1-CG 4.4Å; F269-M325 HydrophobicContact CE2-CE 3.65Å; F269-M325 HydrophobicContact CE2-SD 4.29Å; F269-M325 HydrophobicContact CZ-CE 3.39Å; F269-M325 HydrophobicContact CZ-CG 3.84Å; F269-M325 HydrophobicContact CZ-SD 3.64Å; F269-T327 WeakPolarHBondContact CE1-O 3.38Å; F269-V328 HydrophobicContact CB-CG2 4.26Å; F269-V328 HydrophobicContact CD1-CG2 3.87Å; F269-V328 HydrophobicContact CE1-CG2 4.47Å; F269-V328 HydrophobicContact CG-CG2 4.2Å; F269-L331 HydrophobicContact CD2-CD2 4.46Å; F269-L331 HydrophobicContact CE2-CB 4.41Å; F269-L331 HydrophobicContact CE2-CD2 3.89Å; F269-L331 HydrophobicContact CZ-CB 4.03Å; F269-L331 HydrophobicContact CZ-CD2 4.31Å
270	K	92.6	Very high	91.3	Very high	150 Å²	150	34.1 Å²	34.1	65%	0.652	16%	0.157	S	C	*	.			trans	54.8	33	-178.5	-52.8	-56.2	-173.8	-166.4	0	113.1	A265 M266 D267 F268	A265-K270 PolarHBondContact O-N 3.04Å; M266-K270 VanDerWaalsContact O-CA 3.31Å; M266-K270 WeakPolarHBondContact O-CA 3.5Å; D267-K270 WeakPolarHBondContact O-CD 3.29Å; D267-K270 WeakPolarHBondContact O-CE 3.38Å; D267-K270 PolarHBondContact O-NZ 3Å; F268-K270 VanDerWaalsContact C-N 3.34Å
271	L	93.3	Very high	91.4	Very high	15 Å²	15	34.3 Å²	34.3	8%	0.079	16%	0.159	C	C	.	.			trans	-76.6	136.7	-176.5	-61.8	178	0	0	0	111.6	Y55 A265 F269 Q275 L279 V328	Y55-L271 VanDerWaalsContact CE1-O 3.28Å; Y55-L271 WeakPolarHBondContact CE1-O 3.47Å; Y55-L271 PolarHBondContact OH-O 3.4Å; A265-L271 HydrophobicContact CB-CD1 4.17Å; A265-L271 VanDerWaalsContact O-CB 3.3Å; A265-L271 WeakPolarHBondContact O-CB 3.29Å; A265-L271 WeakPolarHBondContact O-CG 3.45Å; A265-L271 PolarHBondContact O-N 3.42Å; F269-L271 HydrophobicContact CB-CD1 3.91Å; F269-L271 HydrophobicContact CB-CD2 4.23Å; F269-L271 HydrophobicContact CB-CG 3.61Å; F269-L271 PolarHBondContact O-N 3.21Å; L271-Q275 HydrophobicContact CB-CB 4.09Å; L271-Q275 HydrophobicContact CD2-CB 4.11Å; L271-Q275 HydrophobicContact CG-CB 4.5Å; L271-L279 HydrophobicContact CD1-CD1 3.31Å; L271-V328 HydrophobicContact CD1-CG2 4.37Å; L271-V328 HydrophobicContact CD2-CG2 3.91Å
272	E	92.5	Very high	91.4	Very high	101 Å²	101	37.8 Å²	37.8	47%	0.472	17%	0.172	S	C	.	.			trans	-68.4	160.3	168.9	-63.8	-179.8	174.5	0	0	111	Y55 Q274 Q275 N276	Y55-E272 PolarHBondContact OH-O 3.29Å; E272-Q274 PolarHBondContact O-N 3.44Å; E272-Q274 VanDerWaalsContact O-N 3.13Å; E272-Q275 VanDerWaalsContact N-OE1 3.14Å; E272-Q275 PolarHBondContact O-N 3.13Å; E272-N276 PolarHBondContact O-N 2.9Å
273	A	89.7	Confident	91.6	Very high	6 Å²	6	37.9 Å²	37.9	5%	0.05	17%	0.171	C	C	.	.	H	α-helix	trans	-54.8	-36.4	-178.4	0	0	0	0	0	112.9	Y55 G173 G277	Y55-A273 HydrophobicContact CD1-CB 4.12Å; Y55-A273 HydrophobicContact CD2-CB 3.94Å; Y55-A273 HydrophobicContact CE1-CB 4.12Å; Y55-A273 HydrophobicContact CE2-CB 3.96Å; Y55-A273 HydrophobicContact CG-CB 4.03Å; Y55-A273 VanDerWaalsContact CZ-CA 3.42Å; G173-A273 WeakPolarHBondContact CA-O 3.32Å; A273-G277 PolarHBondContact O-N 2.89Å
274	Q	93.4	Very high	91.6	Very high	44 Å²	44	37.6 Å²	37.6	21%	0.206	17%	0.17	C	C	.	.	H	α-helix	trans	-64	-46.8	177.6	-166.7	-173.2	28.9	0	0	112	G173 N174 M177 E272 G277 Y278	G173-Q274 WeakPolarHBondContact O-CA 3.34Å; G173-Q274 PolarHBondContact O-N 3.04Å; N174-Q274 PolarHBondContact OD1-NE2 3.44Å; M177-Q274 HydrophobicContact CB-CB 3.98Å; M177-Q274 HydrophobicContact CG-CB 4.31Å; E272-Q274 PolarHBondContact O-N 3.44Å; E272-Q274 VanDerWaalsContact O-N 3.13Å; Q274-G277 PolarHBondContact O-N 3.41Å; Q274-Y278 HydrophobicContact CG-CD2 4.39Å; Q274-Y278 HydrophobicContact CG-CE2 3.62Å; Q274-Y278 PolarHBondContact NE2-OH 3.16Å; Q274-Y278 WeakPolarHBondContact O-CD2 3.46Å; Q274-Y278 PolarHBondContact O-N 3.33Å
275	Q	93.6	Very high	91.6	Very high	85 Å²	85	41.2 Å²	41.2	40%	0.397	19%	0.189	S	C	.	.	H	α-helix	trans	-66.9	-41.8	-179.6	-65.2	172.9	-35.6	0	0	111.4	L271 E272 G277 Y278 L279	L271-Q275 HydrophobicContact CB-CB 4.09Å; L271-Q275 HydrophobicContact CD2-CB 4.11Å; L271-Q275 HydrophobicContact CG-CB 4.5Å; E272-Q275 VanDerWaalsContact N-OE1 3.14Å; E272-Q275 PolarHBondContact O-N 3.13Å; Q275-G277 VanDerWaalsContact C-N 3.32Å; Q275-G277 PolarHBondContact O-N 3Å; Q275-Y278 PolarHBondContact O-N 3.35Å; Q275-L279 PolarHBondContact O-N 3.27Å
276	N	91.3	Very high	91.5	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-61.5	-40.6	172.8	178.4	61.6	0	0	0	111.9	Y55 A265 E272 Y278 L279 M280	Y55-N276 HydrophobicContact CE2-CB 4.2Å; Y55-N276 WeakPolarHBondContact OH-CB 3.42Å; A265-N276 HydrophobicContact CB-CB 4.34Å; A265-N276 WeakPolarHBondContact CB-OD1 3.27Å; E272-N276 PolarHBondContact O-N 2.9Å; N276-Y278 VanDerWaalsContact C-N 3.32Å; N276-Y278 PolarHBondContact O-N 3.4Å; N276-L279 PolarHBondContact O-N 3.41Å; N276-M280 WeakPolarHBondContact O-CG 3.49Å; N276-M280 PolarHBondContact O-N 3.21Å
277	G	92.4	Very high	91.4	Very high	0 Å²	0	43 Å²	43	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-58.6	-41	173.6	0	0	0	0	0	113.1	S169 A273 Q274 Q275 A281	S169-G277 VanDerWaalsContact CB-O 3.28Å; S169-G277 WeakPolarHBondContact CB-O 3.38Å; S169-G277 WeakPolarHBondContact O-CA 3.21Å; A273-G277 PolarHBondContact O-N 2.89Å; Q274-G277 PolarHBondContact O-N 3.41Å; Q275-G277 VanDerWaalsContact C-N 3.32Å; Q275-G277 PolarHBondContact O-N 3Å; G277-A281 WeakPolarHBondContact O-CB 3.42Å; G277-A281 PolarHBondContact O-N 3.31Å
278	Y	93.6	Very high	91.2	Very high	106 Å²	106	44.9 Å²	44.9	42%	0.416	21%	0.206	S	C	.	.	H	α-helix	trans	-68	-39	175.2	-62.6	-35.2	0	0	0	113.1	T170 N174 Q274 Q275 N276 A281 Y282	T170-Y278 HydrophobicContact CG2-CD1 4.43Å; T170-Y278 HydrophobicContact CG2-CE1 4.06Å; N174-Y278 WeakPolarHBondContact ND2-CE1 3.49Å; N174-Y278 PolarHBondContact ND2-OH 2.7Å; N174-Y278 PolarHBondContact OD1-OH 3.22Å; Q274-Y278 HydrophobicContact CG-CD2 4.39Å; Q274-Y278 HydrophobicContact CG-CE2 3.62Å; Q274-Y278 PolarHBondContact NE2-OH 3.16Å; Q274-Y278 WeakPolarHBondContact O-CD2 3.46Å; Q274-Y278 PolarHBondContact O-N 3.33Å; Q275-Y278 PolarHBondContact O-N 3.35Å; N276-Y278 VanDerWaalsContact C-N 3.32Å; N276-Y278 PolarHBondContact O-N 3.4Å; Y278-A281 PolarHBondContact O-N 3.4Å; Y278-Y282 WeakPolarHBondContact O-CB 3.48Å; Y278-Y282 PolarHBondContact O-N 3.4Å
279	L	92.5	Very high	91	Very high	14 Å²	14	45.5 Å²	45.5	7%	0.073	22%	0.217	C	C	.	.	H	α-helix	trans	-65.3	-42.7	175.3	-73.6	175.9	0	0	0	112	F261 L271 Q275 N276 A281 Y282 F283 V328 L331	F261-L279 HydrophobicContact CE1-CB 4.32Å; F261-L279 HydrophobicContact CZ-CB 3.97Å; F261-L279 HydrophobicContact CZ-CD1 4.06Å; L271-L279 HydrophobicContact CD1-CD1 3.31Å; Q275-L279 PolarHBondContact O-N 3.27Å; N276-L279 PolarHBondContact O-N 3.41Å; L279-A281 VanDerWaalsContact C-N 3.32Å; L279-A281 PolarHBondContact O-N 3.5Å; L279-Y282 WeakPolarHBondContact O-CB 3.46Å; L279-Y282 PolarHBondContact O-N 2.99Å; L279-Y282 VanDerWaalsContact O-N 3.17Å; L279-F283 WeakPolarHBondContact O-CD1 3.23Å; L279-F283 PolarHBondContact O-N 3.21Å; L279-V328 HydrophobicContact CD1-CG1 4.18Å; L279-V328 HydrophobicContact CD2-CG1 4.16Å; L279-L331 HydrophobicContact CD1-CD2 3.88Å; L279-L331 HydrophobicContact CD2-CD2 4.48Å
280	M	90.7	Very high	90.9	Very high	21 Å²	21	44.8 Å²	44.8	10%	0.103	21%	0.214	C	C	.	.	H	α-helix	trans	-62.6	-39	174.5	-73.5	-67.4	-151.7	0	0	112	S169 F261 S262 N276 F283 G284	S169-M280 WeakPolarHBondContact OG-CB 3.44Å; F261-M280 HydrophobicContact CD1-CE 3.58Å; F261-M280 HydrophobicContact CD1-CG 4.44Å; F261-M280 HydrophobicContact CD1-SD 3.62Å; F261-M280 HydrophobicContact CE1-CE 4.17Å; F261-M280 HydrophobicContact CE1-CG 4.13Å; F261-M280 HydrophobicContact CE1-SD 3.83Å; S262-M280 WeakPolarHBondContact OG-CE 3.05Å; N276-M280 WeakPolarHBondContact O-CG 3.49Å; N276-M280 PolarHBondContact O-N 3.21Å; M280-F283 WeakPolarHBondContact O-CB 3.28Å; M280-F283 PolarHBondContact O-N 3.45Å; M280-G284 PolarHBondContact O-N 3.03Å
281	A	92.2	Very high	90.4	Very high	7 Å²	7	41.9 Å²	41.9	6%	0.058	20%	0.203	C	C	.	.	H	α-helix	trans	-63.5	-41.6	172.6	0	0	0	0	0	111.9	I166 G277 Y278 L279 F283 G284 I285	I166-A281 HydrophobicContact CG2-CB 4.35Å; G277-A281 WeakPolarHBondContact O-CB 3.42Å; G277-A281 PolarHBondContact O-N 3.31Å; Y278-A281 PolarHBondContact O-N 3.4Å; L279-A281 VanDerWaalsContact C-N 3.32Å; L279-A281 PolarHBondContact O-N 3.5Å; A281-F283 VanDerWaalsContact C-N 3.34Å; A281-F283 PolarHBondContact O-N 3.39Å; A281-G284 PolarHBondContact O-N 2.95Å; A281-I285 WeakPolarHBondContact O-CG1 3.49Å; A281-I285 PolarHBondContact O-N 3.15Å
282	Y	92	Very high	89.6	Confident	73 Å²	73	44.6 Å²	44.6	29%	0.286	23%	0.234	S	C	.	.	H	α-helix	trans	-59.8	-42.5	173.7	172.4	-118.3	0	0	0	112	Y278 L279 G284 I285 V286 C332 V335 T336	Y278-Y282 WeakPolarHBondContact O-CB 3.48Å; Y278-Y282 PolarHBondContact O-N 3.4Å; L279-Y282 WeakPolarHBondContact O-CB 3.46Å; L279-Y282 PolarHBondContact O-N 2.99Å; L279-Y282 VanDerWaalsContact O-N 3.17Å; Y282-G284 VanDerWaalsContact C-N 3.3Å; Y282-G284 PolarHBondContact O-N 3.03Å; Y282-I285 PolarHBondContact O-N 3.35Å; Y282-V286 HydrophobicContact CD2-CG2 3.98Å; Y282-V286 HydrophobicContact CE1-CG2 4.29Å; Y282-V286 HydrophobicContact CE2-CG2 3.48Å; Y282-V286 VanDerWaalsContact CE2-CG2 3.48Å; Y282-V286 WeakPolarHBondContact O-CG2 3.36Å; Y282-V286 PolarHBondContact O-N 2.95Å; Y282-C332 HydrophobicContact CE1-CB 4.38Å; Y282-C332 PolarHBondContact OH-O 2.9Å; Y282-V335 HydrophobicContact CD1-CB 4.44Å; Y282-V335 HydrophobicContact CD1-CG1 4.02Å; Y282-V335 HydrophobicContact CE1-CB 3.74Å; Y282-V335 HydrophobicContact CE1-CG1 3.6Å; Y282-V335 HydrophobicContact CE1-CG2 4.2Å; Y282-T336 PolarHBondContact OH-OG1 3.31Å
283	F	88.9	Confident	89	Confident	15 Å²	15	41.2 Å²	41.2	7%	0.066	23%	0.227	C	C	.	.	H	α-helix	trans	-59.2	-44.8	174.9	-74.2	24.8	0	0	0	110.7	F261 L279 M280 A281 I285 V286 Q287 V335 W338	F261-F283 AromaticContact CD1-CE2 3.89Å; F261-F283 HydrophobicContact CD1-CE2 3.89Å; F261-F283 HydrophobicContact CD1-CZ 4.23Å; F261-F283 AromaticContact CD2-CE2 3.9Å; F261-F283 HydrophobicContact CD2-CE2 3.9Å; F261-F283 AromaticContact CD2-CZ 3.78Å; F261-F283 HydrophobicContact CD2-CZ 3.78Å; F261-F283 AromaticContact CE1-CE2 3.97Å; F261-F283 HydrophobicContact CE1-CE2 3.97Å; F261-F283 AromaticContact CE1-CZ 3.91Å; F261-F283 HydrophobicContact CE1-CZ 3.91Å; F261-F283 HydrophobicContact CE2-CE1 4.34Å; F261-F283 HydrophobicContact CE2-CE2 4Å; F261-F283 AromaticContact CE2-CZ 3.44Å; F261-F283 HydrophobicContact CE2-CZ 3.44Å; F261-F283 VanDerWaalsContact CE2-CZ 3.44Å; F261-F283 AromaticContact CG-CE2 3.86Å; F261-F283 HydrophobicContact CG-CE2 3.86Å; F261-F283 HydrophobicContact CG-CZ 4.17Å; F261-F283 HydrophobicContact CZ-CE1 4.1Å; F261-F283 HydrophobicContact CZ-CE2 4.03Å; F261-F283 AromaticContact CZ-CZ 3.5Å; F261-F283 HydrophobicContact CZ-CZ 3.5Å; L279-F283 WeakPolarHBondContact O-CD1 3.23Å; L279-F283 PolarHBondContact O-N 3.21Å; M280-F283 WeakPolarHBondContact O-CB 3.28Å; M280-F283 PolarHBondContact O-N 3.45Å; A281-F283 VanDerWaalsContact C-N 3.34Å; A281-F283 PolarHBondContact O-N 3.39Å; F283-I285 PolarHBondContact O-N 3.06Å; F283-V286 PolarHBondContact O-N 3.29Å; F283-Q287 VanDerWaalsContact O-CB 3.23Å; F283-Q287 WeakPolarHBondContact O-CB 3.43Å; F283-Q287 PolarHBondContact O-N 3.46Å; F283-V335 HydrophobicContact CD1-CB 4.38Å; F283-V335 HydrophobicContact CD1-CG1 3.58Å; F283-V335 HydrophobicContact CD1-CG2 3.82Å; F283-V335 HydrophobicContact CE1-CB 4.17Å; F283-V335 HydrophobicContact CE1-CG1 3.86Å; F283-V335 HydrophobicContact CE1-CG2 3.16Å; F283-V335 HydrophobicContact CG-CG1 4.24Å; F283-V335 HydrophobicContact CZ-CG2 3.68Å; F283-W338 HydrophobicContact CD2-CZ3 4.21Å; F283-W338 HydrophobicContact CE2-CE3 4.46Å; F283-W338 HydrophobicContact CE2-CH2 4.12Å; F283-W338 AromaticContact CE2-CZ3 3.47Å; F283-W338 HydrophobicContact CE2-CZ3 3.47Å; F283-W338 VanDerWaalsContact CE2-CZ3 3.47Å; F283-W338 AromaticContact CZ-CZ3 3.89Å; F283-W338 HydrophobicContact CZ-CZ3 3.89Å
284	G	87.8	Confident	88.9	Confident	1 Å²	1	44.2 Å²	44.2	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-60.3	-42.5	176.6	0	0	0	0	0	113.5	M165 M280 A281 Y282 Q287 M288	M165-G284 WeakPolarHBondContact SD-CA 3.5Å; M280-G284 PolarHBondContact O-N 3.03Å; A281-G284 PolarHBondContact O-N 2.95Å; Y282-G284 VanDerWaalsContact C-N 3.3Å; Y282-G284 PolarHBondContact O-N 3.03Å; G284-Q287 PolarHBondContact O-N 3.25Å; G284-M288 VanDerWaalsContact O-CB 3.26Å; G284-M288 WeakPolarHBondContact O-CB 3.26Å; G284-M288 PolarHBondContact O-N 3.43Å
285	I	91.2	Very high	88.6	Confident	77 Å²	77	43.2 Å²	43.2	40%	0.395	24%	0.237	S	C	.	.	H	α-helix	trans	-62.3	-51.3	176.2	-67.4	166.6	0	0	0	110.4	I166 A281 Y282 F283 Q287 M288 V289	I166-I285 HydrophobicContact CD1-CG1 3.57Å; I166-I285 HydrophobicContact CG1-CG1 3.96Å; A281-I285 WeakPolarHBondContact O-CG1 3.49Å; A281-I285 PolarHBondContact O-N 3.15Å; Y282-I285 PolarHBondContact O-N 3.35Å; F283-I285 PolarHBondContact O-N 3.06Å; I285-Q287 VanDerWaalsContact C-N 3.33Å; I285-Q287 PolarHBondContact O-N 3.49Å; I285-M288 PolarHBondContact O-N 3.47Å; I285-V289 WeakPolarHBondContact O-CG2 3.42Å; I285-V289 PolarHBondContact O-N 2.75Å
286	V	90.8	Very high	88.2	Confident	14 Å²	14	41.3 Å²	41.3	9%	0.085	24%	0.24	C	C	.	.	H	α-helix	trans	-59.9	-45.9	179.8	173.6	0	0	0	0	110.5	Y282 F283 M288 V289 V290 V335 M339	Y282-V286 HydrophobicContact CD2-CG2 3.98Å; Y282-V286 HydrophobicContact CE1-CG2 4.29Å; Y282-V286 HydrophobicContact CE2-CG2 3.48Å; Y282-V286 VanDerWaalsContact CE2-CG2 3.48Å; Y282-V286 WeakPolarHBondContact O-CG2 3.36Å; Y282-V286 PolarHBondContact O-N 2.95Å; F283-V286 PolarHBondContact O-N 3.29Å; V286-M288 PolarHBondContact O-N 3.36Å; V286-V289 PolarHBondContact O-N 2.89Å; V286-V290 HydrophobicContact CG1-CG2 4.33Å; V286-V290 WeakPolarHBondContact O-CB 3.25Å; V286-V290 VanDerWaalsContact O-CG2 3.29Å; V286-V290 WeakPolarHBondContact O-CG2 3.34Å; V286-V290 PolarHBondContact O-N 3.2Å; V286-V335 HydrophobicContact CB-CG1 4.49Å; V286-V335 HydrophobicContact CG2-CG1 4.33Å; V286-M339 HydrophobicContact CG1-CB 3.71Å; V286-M339 HydrophobicContact CG1-CG 4.01Å
287	Q	86.2	Confident	88.1	Confident	39 Å²	39	48.9 Å²	48.9	18%	0.182	27%	0.269	C	S	.	.	H	α-helix	trans	-60.4	-44.7	177.9	-174.4	176.5	21	0	0	111.6	M165 F283 G284 I285 V289 V290 Q291 M339	M165-Q287 VanDerWaalsContact CE-OE1 3.31Å; F283-Q287 VanDerWaalsContact O-CB 3.23Å; F283-Q287 WeakPolarHBondContact O-CB 3.43Å; F283-Q287 PolarHBondContact O-N 3.46Å; G284-Q287 PolarHBondContact O-N 3.25Å; I285-Q287 VanDerWaalsContact C-N 3.33Å; I285-Q287 PolarHBondContact O-N 3.49Å; Q287-V289 PolarHBondContact O-N 2.84Å; Q287-V290 PolarHBondContact O-N 3.03Å; Q287-Q291 HydrophobicContact CG-CG 4.27Å; Q287-Q291 VanDerWaalsContact NE2-NE2 3.15Å; Q287-Q291 WeakPolarHBondContact O-CB 3.41Å; Q287-Q291 WeakPolarHBondContact O-CG 3.44Å; Q287-Q291 PolarHBondContact O-N 3.38Å; Q287-M339 HydrophobicContact CB-SD 4.46Å
288	M	85.8	Confident	88	Confident	71 Å²	71	50 Å²	50	35%	0.35	28%	0.275	S	S	.	.	H	α-helix	trans	-62.9	-41.5	178.2	-173.6	178.1	68.3	0	0	111.8	L159 G284 I285 V286 G292	L159-M288 HydrophobicContact CD1-SD 4.18Å; G284-M288 VanDerWaalsContact O-CB 3.26Å; G284-M288 WeakPolarHBondContact O-CB 3.26Å; G284-M288 PolarHBondContact O-N 3.43Å; I285-M288 PolarHBondContact O-N 3.47Å; V286-M288 PolarHBondContact O-N 3.36Å; M288-G292 WeakPolarHBondContact O-CA 3.39Å; M288-G292 PolarHBondContact O-N 3.24Å
289	V	88.6	Confident	87.7	Confident	92 Å²	92	47.7 Å²	47.7	56%	0.558	27%	0.272	S	S	*	.	H	α-helix	trans	-66.2	-46.2	177	171.6	0	0	0	0	111.2	I285 V286 Q287 G293 L294	I285-V289 WeakPolarHBondContact O-CG2 3.42Å; I285-V289 PolarHBondContact O-N 2.75Å; V286-V289 PolarHBondContact O-N 2.89Å; Q287-V289 PolarHBondContact O-N 2.84Å; V289-G293 WeakPolarHBondContact O-CA 3.33Å; V289-G293 PolarHBondContact O-N 3.2Å; V289-L294 PolarHBondContact O-N 3.17Å
290	V	88.9	Confident	87.6	Confident	9 Å²	9	51.4 Å²	51.4	6%	0.055	30%	0.299	C	S	.	.	I	π-helix	trans	-64.3	-52	-179.9	167.4	0	0	0	0	111.1	V286 Q287 L294 I295 F340	V286-V290 HydrophobicContact CG1-CG2 4.33Å; V286-V290 WeakPolarHBondContact O-CB 3.25Å; V286-V290 VanDerWaalsContact O-CG2 3.29Å; V286-V290 WeakPolarHBondContact O-CG2 3.34Å; V286-V290 PolarHBondContact O-N 3.2Å; Q287-V290 PolarHBondContact O-N 3.03Å; V290-L294 WeakPolarHBondContact O-CB 3.14Å; V290-L294 PolarHBondContact O-N 3.14Å; V290-L294 VanDerWaalsContact O-N 3.15Å; V290-I295 PolarHBondContact O-N 3.03Å; V290-F340 HydrophobicContact CG1-CD2 4.27Å; V290-F340 HydrophobicContact CG2-CB 4.39Å
291	Q	82.1	Confident	87.7	Confident	90 Å²	90	60 Å²	60	42%	0.421	33%	0.33	S	S	.	.	I	π-helix	trans	-75.3	-39.3	-176	-65.8	-168.6	15.2	0	0	112.5	Q287 I295 S343	Q287-Q291 HydrophobicContact CG-CG 4.27Å; Q287-Q291 VanDerWaalsContact NE2-NE2 3.15Å; Q287-Q291 WeakPolarHBondContact O-CB 3.41Å; Q287-Q291 WeakPolarHBondContact O-CG 3.44Å; Q287-Q291 PolarHBondContact O-N 3.38Å; Q291-I295 WeakPolarHBondContact O-CG2 3.45Å; Q291-S343 PolarHBondContact NE2-OG 3.4Å
292	G	77.4	Confident	87.8	Confident	71 Å²	71	64.9 Å²	64.9	73%	0.732	35%	0.35	S	S	*	.	I	π-helix	trans	-79.2	-33.8	-178.5	0	0	0	0	0	114	M288	M288-G292 WeakPolarHBondContact O-CA 3.39Å; M288-G292 PolarHBondContact O-N 3.24Å
293	G	80.8	Confident	87.9	Confident	31 Å²	31	65.2 Å²	65.2	32%	0.32	36%	0.362	S	S	.	.	I	π-helix	trans	-109.4	-40.2	-171.7	0	0	0	0	0	115.4	V289 R297	V289-G293 WeakPolarHBondContact O-CA 3.33Å; V289-G293 PolarHBondContact O-N 3.2Å; G293-R297 PolarHBondContact O-NH1 3.31Å
294	L	87.1	Confident	88.1	Confident	69 Å²	69	66.6 Å²	66.6	36%	0.361	37%	0.368	S	S	.	.	I	π-helix	trans	-97.3	-42	-165.9	-169.4	57.4	0	0	0	112.7	V289 V290 G296 R297 L298 F340	V289-L294 PolarHBondContact O-N 3.17Å; V290-L294 WeakPolarHBondContact O-CB 3.14Å; V290-L294 PolarHBondContact O-N 3.14Å; V290-L294 VanDerWaalsContact O-N 3.15Å; L294-G296 PolarHBondContact O-N 2.96Å; L294-R297 PolarHBondContact O-N 3.05Å; L294-L298 HydrophobicContact CD1-CD1 3.44Å; L294-L298 VanDerWaalsContact CD1-CD1 3.44Å; L294-L298 HydrophobicContact CG-CD1 3.77Å; L294-L298 HydrophobicContact CG-CD2 4.38Å; L294-L298 WeakPolarHBondContact O-CD1 3.43Å; L294-L298 PolarHBondContact O-N 3.35Å; L294-L298 VanDerWaalsContact O-N 3.1Å; L294-F340 HydrophobicContact CD2-CD2 3.66Å; L294-F340 HydrophobicContact CD2-CE2 3.5Å; L294-F340 VanDerWaalsContact CD2-CE2 3.5Å; L294-F340 HydrophobicContact CG-CE2 4.19Å
295	I	87.2	Confident	88.3	Confident	22 Å²	22	72.9 Å²	72.9	11%	0.113	40%	0.395	C	S	.	.	H	α-helix	trans	-61.3	-45.3	-167.7	-149.2	146.6	0	0	0	113	V290 Q291 R297 L298 T299 S343 V344 V347	V290-I295 PolarHBondContact O-N 3.03Å; Q291-I295 WeakPolarHBondContact O-CG2 3.45Å; I295-R297 VanDerWaalsContact C-N 3.29Å; I295-R297 PolarHBondContact O-N 3.1Å; I295-L298 PolarHBondContact O-N 3.06Å; I295-L298 VanDerWaalsContact O-N 3.1Å; I295-T299 HydrophobicContact CG1-CG2 4.39Å; I295-T299 WeakPolarHBondContact O-CG2 3.43Å; I295-T299 PolarHBondContact O-N 2.9Å; I295-T299 PolarHBondContact O-OG1 3.22Å; I295-T299 VanDerWaalsContact O-OG1 3.08Å; I295-S343 WeakPolarHBondContact CD1-O 3.38Å; I295-V344 HydrophobicContact CD1-CG2 4.33Å; I295-V344 HydrophobicContact CG1-CG2 4.48Å; I295-V347 HydrophobicContact CD1-CB 3.91Å; I295-V347 HydrophobicContact CD1-CG1 4.47Å; I295-V347 HydrophobicContact CD1-CG2 3.48Å; I295-V347 VanDerWaalsContact CD1-CG2 3.48Å; I295-V347 HydrophobicContact CG1-CB 4.33Å; I295-V347 HydrophobicContact CG1-CG1 4.38Å; I295-V347 HydrophobicContact CG1-CG2 4.19Å
296	G	84.6	Confident	88.4	Confident	45 Å²	45	72.1 Å²	72.1	46%	0.464	40%	0.397	S	S	.	.	H	α-helix	trans	-64.7	-30.8	-179.4	0	0	0	0	0	113.7	L294 T299 S300	L294-G296 PolarHBondContact O-N 2.96Å; G296-T299 WeakPolarHBondContact CA-OG1 3.37Å; G296-T299 PolarHBondContact O-OG1 3.08Å; G296-S300 WeakPolarHBondContact O-CB 3.3Å; G296-S300 PolarHBondContact O-N 3.42Å; G296-S300 PolarHBondContact O-OG 2.95Å
297	R	88.6	Confident	88.7	Confident	159 Å²	159	71.6 Å²	71.6	60%	0.6	39%	0.393	S	S	*	.	H	α-helix	trans	-73.7	-36.4	174.1	-68.9	-174.1	174.4	95.4	-4.6	111.7	G293 L294 I295 S300 R301	G293-R297 PolarHBondContact O-NH1 3.31Å; L294-R297 PolarHBondContact O-N 3.05Å; I295-R297 VanDerWaalsContact C-N 3.29Å; I295-R297 PolarHBondContact O-N 3.1Å; R297-S300 PolarHBondContact O-OG 3.2Å; R297-S300 VanDerWaalsContact O-OG 3.1Å; R297-R301 WeakPolarHBondContact O-CB 3.33Å; R297-R301 VanDerWaalsContact O-CG 3.3Å; R297-R301 WeakPolarHBondContact O-CG 3.47Å; R297-R301 PolarHBondContact O-N 3.36Å
298	L	90.1	Very high	89.2	Confident	25 Å²	25	70 Å²	70	13%	0.131	39%	0.386	C	S	.	.	H	α-helix	trans	-71.5	-47.6	178.2	-95.5	61.9	0	0	0	111.4	L294 I295 S300 R301 F302 L307 F340 V344	L294-L298 HydrophobicContact CD1-CD1 3.44Å; L294-L298 VanDerWaalsContact CD1-CD1 3.44Å; L294-L298 HydrophobicContact CG-CD1 3.77Å; L294-L298 HydrophobicContact CG-CD2 4.38Å; L294-L298 WeakPolarHBondContact O-CD1 3.43Å; L294-L298 PolarHBondContact O-N 3.35Å; L294-L298 VanDerWaalsContact O-N 3.1Å; I295-L298 PolarHBondContact O-N 3.06Å; I295-L298 VanDerWaalsContact O-N 3.1Å; L298-S300 PolarHBondContact O-N 3.33Å; L298-R301 PolarHBondContact O-N 2.91Å; L298-R301 VanDerWaalsContact O-N 3.15Å; L298-F302 HydrophobicContact CG-CD2 4.3Å; L298-F302 HydrophobicContact CG-CE2 4.47Å; L298-F302 PolarHBondContact O-N 3.31Å; L298-L307 HydrophobicContact CB-CD2 4.31Å; L298-L307 HydrophobicContact CD2-CD2 4.38Å; L298-L307 HydrophobicContact CG-CD2 4.49Å; L298-F340 HydrophobicContact CD2-CE2 3.51Å; L298-F340 HydrophobicContact CD2-CZ 3.46Å; L298-F340 VanDerWaalsContact CD2-CZ 3.46Å; L298-V344 HydrophobicContact CD2-CG2 4.47Å
299	T	89.3	Confident	89.7	Confident	56 Å²	56	67.7 Å²	67.7	34%	0.344	38%	0.375	S	S	.	.	H	α-helix	trans	-65.3	-24.1	-178.6	55	0	0	0	0	113.1	I295 G296 L307 V347 I348	I295-T299 HydrophobicContact CG1-CG2 4.39Å; I295-T299 WeakPolarHBondContact O-CG2 3.43Å; I295-T299 PolarHBondContact O-N 2.9Å; I295-T299 PolarHBondContact O-OG1 3.22Å; I295-T299 VanDerWaalsContact O-OG1 3.08Å; G296-T299 WeakPolarHBondContact CA-OG1 3.37Å; G296-T299 PolarHBondContact O-OG1 3.08Å; T299-L307 HydrophobicContact CG2-CD1 4.44Å; T299-V347 HydrophobicContact CG2-CG1 4.13Å; T299-I348 HydrophobicContact CG2-CD1 3.96Å
300	S	89.4	Confident	90.1	Very high	93 Å²	93	67.2 Å²	67.2	65%	0.65	37%	0.369	S	S	*	.	H	α-helix	trans	-85.4	-25.5	175.1	55.6	0	0	0	0	113.6	G296 R297 L298	G296-S300 WeakPolarHBondContact O-CB 3.3Å; G296-S300 PolarHBondContact O-N 3.42Å; G296-S300 PolarHBondContact O-OG 2.95Å; R297-S300 PolarHBondContact O-OG 3.2Å; R297-S300 VanDerWaalsContact O-OG 3.1Å; L298-S300 PolarHBondContact O-N 3.33Å
301	R	93.2	Very high	90.4	Very high	200 Å²	200	66.8 Å²	66.8	76%	0.755	37%	0.366	S	S	*	.	H	α-helix	trans	-96.1	-30.4	-177.1	-72.6	-175.4	178.2	-169.1	-0.4	114.5	R297 L298	R297-R301 WeakPolarHBondContact O-CB 3.33Å; R297-R301 VanDerWaalsContact O-CG 3.3Å; R297-R301 WeakPolarHBondContact O-CG 3.47Å; R297-R301 PolarHBondContact O-N 3.36Å; L298-R301 PolarHBondContact O-N 2.91Å; L298-R301 VanDerWaalsContact O-N 3.15Å
302	F	93.9	Very high	91.2	Very high	110 Å²	110	62.5 Å²	62.5	48%	0.482	35%	0.346	S	S	.	.	S	Bend	trans	-118.2	145.9	-172.5	-63.3	-78.8	0	0	0	111.8	L298 L307	L298-F302 HydrophobicContact CG-CD2 4.3Å; L298-F302 HydrophobicContact CG-CE2 4.47Å; L298-F302 PolarHBondContact O-N 3.31Å; F302-L307 HydrophobicContact CB-CD1 3.97Å; F302-L307 HydrophobicContact CB-CD2 3.78Å; F302-L307 HydrophobicContact CB-CG 3.71Å; F302-L307 HydrophobicContact CD2-CD2 4.31Å; F302-L307 HydrophobicContact CG-CD2 4.28Å
303	P	94	Very high	92.1	Very high	81 Å²	81	60.2 Å²	60.2	53%	0.526	32%	0.323	S	S	.	.			trans	-68.7	144.6	176.8	28.7	-33.8	0	0	0	111.1	K305 S306 L307	P303-K305 PolarHBondContact O-N 2.92Å; P303-S306 WeakPolarHBondContact CG-OG 3.43Å; P303-S306 PolarHBondContact O-N 3.2Å; P303-L307 PolarHBondContact O-N 3.39Å; P303-L307 VanDerWaalsContact O-N 3.11Å
304	E	92.8	Very high	92.9	Very high	43 Å²	43	61 Å²	61	20%	0.201	32%	0.319	C	S	.	.	H	α-helix	trans	-55.9	-37.7	-176.3	-65.2	-175.9	155.7	0	0	113	S306 L307 L308 I348 S351 M352 K355	E304-S306 PolarHBondContact O-N 3.48Å; E304-L307 PolarHBondContact O-N 2.79Å; E304-L308 WeakPolarHBondContact O-CB 3.37Å; E304-L308 PolarHBondContact O-N 3.45Å; E304-I348 HydrophobicContact CB-CD1 4.35Å; E304-I348 HydrophobicContact CB-CG2 4.06Å; E304-I348 HydrophobicContact CG-CD1 4.09Å; E304-I348 WeakPolarHBondContact O-CG2 3.46Å; E304-S351 WeakPolarHBondContact OE1-CB 3.43Å; E304-S351 PolarHBondContact OE1-OG 3.25Å; E304-M352 HydrophobicContact CB-CG 4.09Å; E304-M352 HydrophobicContact CB-SD 4.3Å; E304-M352 VanDerWaalsContact OE2-CG 3.31Å; E304-M352 WeakPolarHBondContact OE2-CG 3.46Å; E304-K355 VanDerWaalsContact CD-NZ 3.33Å; E304-K355 WeakPolarHBondContact OE1-CE 3.38Å; E304-K355 IonicContact OE1-NZ 3.58Å; E304-K355 PolarHBondContact OE1-NZ 2.92Å; E304-K355 IonicContact OE2-NZ 2.74Å
305	K	92.7	Very high	93.4	Very high	134 Å²	134	57.9 Å²	57.9	58%	0.583	30%	0.303	S	S	*	.	H	α-helix	trans	-62.8	-39.8	178.5	-68	-178.1	-177.6	173.4	0	112.8	P303 L309 Q415	P303-K305 PolarHBondContact O-N 2.92Å; K305-L309 PolarHBondContact O-N 3.32Å; K305-L309 VanDerWaalsContact O-N 3.11Å; K305-Q415 PolarHBondContact O-NE2 3.28Å
306	S	93.9	Very high	93.9	Very high	60 Å²	60	57 Å²	57	42%	0.42	30%	0.299	S	S	.	.	H	α-helix	trans	-73.7	-38.3	178.2	-58.8	0	0	0	0	111.1	P303 E304 L308 L309 L310	P303-S306 WeakPolarHBondContact CG-OG 3.43Å; P303-S306 PolarHBondContact O-N 3.2Å; E304-S306 PolarHBondContact O-N 3.48Å; S306-L308 VanDerWaalsContact C-N 3.34Å; S306-L309 PolarHBondContact O-N 2.99Å; S306-L310 VanDerWaalsContact O-CB 3.28Å; S306-L310 WeakPolarHBondContact O-CB 3.5Å; S306-L310 PolarHBondContact O-N 3.05Å
307	L	95.8	Very high	94.5	Very high	3 Å²	3	56.8 Å²	56.8	2%	0.016	30%	0.297	C	S	.	.	H	α-helix	trans	-66.4	-36	174.6	-69	175.5	0	0	0	112.3	L298 T299 F302 P303 E304 S311 V344 I348	L298-L307 HydrophobicContact CB-CD2 4.31Å; L298-L307 HydrophobicContact CD2-CD2 4.38Å; L298-L307 HydrophobicContact CG-CD2 4.49Å; T299-L307 HydrophobicContact CG2-CD1 4.44Å; F302-L307 HydrophobicContact CB-CD1 3.97Å; F302-L307 HydrophobicContact CB-CD2 3.78Å; F302-L307 HydrophobicContact CB-CG 3.71Å; F302-L307 HydrophobicContact CD2-CD2 4.31Å; F302-L307 HydrophobicContact CG-CD2 4.28Å; P303-L307 PolarHBondContact O-N 3.39Å; P303-L307 VanDerWaalsContact O-N 3.11Å; E304-L307 PolarHBondContact O-N 2.79Å; L307-S311 WeakPolarHBondContact O-CB 3.25Å; L307-S311 PolarHBondContact O-N 3.5Å; L307-S311 PolarHBondContact O-OG 3.13Å; L307-V344 HydrophobicContact CB-CG1 4.09Å; L307-I348 HydrophobicContact CB-CD1 4.02Å; L307-I348 HydrophobicContact CB-CG1 3.89Å; L307-I348 HydrophobicContact CD1-CD1 3.71Å; L307-I348 HydrophobicContact CD1-CG1 4.34Å
308	L	96.3	Very high	94.9	Very high	6 Å²	6	49.4 Å²	49.4	3%	0.031	27%	0.27	C	S	.	.	H	α-helix	trans	-63.5	-47.4	173.1	-177.1	63.6	0	0	0	111	E304 S306 S311 I312 F345 I348 T349 M352 L411	E304-L308 WeakPolarHBondContact O-CB 3.37Å; E304-L308 PolarHBondContact O-N 3.45Å; S306-L308 VanDerWaalsContact C-N 3.34Å; L308-S311 PolarHBondContact O-N 2.96Å; L308-S311 PolarHBondContact O-OG 3.06Å; L308-I312 HydrophobicContact CD1-CD1 3.8Å; L308-I312 HydrophobicContact CD1-CG1 4.41Å; L308-I312 HydrophobicContact CG-CD1 3.91Å; L308-I312 VanDerWaalsContact O-CG1 3.31Å; L308-I312 WeakPolarHBondContact O-CG1 3.42Å; L308-I312 PolarHBondContact O-N 3Å; L308-I312 VanDerWaalsContact O-N 3.11Å; L308-F345 HydrophobicContact CD1-CD2 3.99Å; L308-F345 HydrophobicContact CD1-CE2 4.16Å; L308-I348 HydrophobicContact CB-CG2 4Å; L308-T349 HydrophobicContact CD1-CG2 3.92Å; L308-M352 HydrophobicContact CD2-CE 4.48Å; L308-M352 HydrophobicContact CD2-SD 4.04Å; L308-L411 HydrophobicContact CD2-CD1 4.18Å; L308-L411 HydrophobicContact CG-CD1 4.29Å
309	L	96.5	Very high	95.3	Very high	22 Å²	22	48.2 Å²	48.2	12%	0.115	26%	0.264	C	S	.	.	H	α-helix	trans	-63.8	-44.4	178.3	-171.3	69.9	0	0	0	111.5	K305 S306 I312 G313 F408 L411 L412	K305-L309 PolarHBondContact O-N 3.32Å; K305-L309 VanDerWaalsContact O-N 3.11Å; S306-L309 PolarHBondContact O-N 2.99Å; L309-I312 PolarHBondContact O-N 3.27Å; L309-G313 PolarHBondContact O-N 3.16Å; L309-F408 HydrophobicContact CD1-CD2 3.54Å; L309-F408 HydrophobicContact CD1-CE2 3.57Å; L309-F408 HydrophobicContact CD1-CG 4.1Å; L309-F408 HydrophobicContact CD1-CZ 4.11Å; L309-F408 HydrophobicContact CD2-CE2 4.38Å; L309-F408 HydrophobicContact CD2-CZ 4.49Å; L309-F408 HydrophobicContact CG-CD2 4.01Å; L309-F408 HydrophobicContact CG-CE2 3.55Å; L309-F408 HydrophobicContact CG-CZ 4.12Å; L309-F408 WeakPolarHBondContact O-CD2 3.14Å; L309-F408 VanDerWaalsContact O-CE2 3.31Å; L309-F408 WeakPolarHBondContact O-CE2 3.22Å; L309-L411 HydrophobicContact CD1-CB 3.98Å; L309-L412 HydrophobicContact CD1-CB 4.36Å; L309-L412 HydrophobicContact CD2-CD1 3.94Å
310	L	96.8	Very high	95.6	Very high	82 Å²	82	48.8 Å²	48.8	43%	0.429	26%	0.264	S	S	.	.	H	α-helix	trans	-59.7	-48.9	176.8	178.6	67.4	0	0	0	111.8	S306 G313 I314 F340	S306-L310 VanDerWaalsContact O-CB 3.28Å; S306-L310 WeakPolarHBondContact O-CB 3.5Å; S306-L310 PolarHBondContact O-N 3.05Å; L310-G313 PolarHBondContact O-N 3.48Å; L310-I314 HydrophobicContact CD1-CD1 3.87Å; L310-I314 HydrophobicContact CD1-CG1 4.31Å; L310-I314 HydrophobicContact CG-CD1 3.89Å; L310-I314 VanDerWaalsContact O-CG1 3.3Å; L310-I314 WeakPolarHBondContact O-CG1 3.48Å; L310-I314 PolarHBondContact O-N 3.35Å; L310-F340 HydrophobicContact CD2-CE1 4.49Å
311	S	96.8	Very high	96	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-61	-48.1	-179.6	52	0	0	0	0	111.5	L307 L308 G313 I314 T315 S341	L307-S311 WeakPolarHBondContact O-CB 3.25Å; L307-S311 PolarHBondContact O-N 3.5Å; L307-S311 PolarHBondContact O-OG 3.13Å; L308-S311 PolarHBondContact O-N 2.96Å; L308-S311 PolarHBondContact O-OG 3.06Å; S311-G313 VanDerWaalsContact C-N 3.34Å; S311-G313 PolarHBondContact O-N 3.47Å; S311-I314 PolarHBondContact O-N 3.15Å; S311-T315 WeakPolarHBondContact O-CB 3.45Å; S311-T315 PolarHBondContact O-N 2.71Å; S311-T315 PolarHBondContact O-OG1 3.04Å; S311-S341 WeakPolarHBondContact CB-O 3.33Å; S311-S341 WeakPolarHBondContact O-CB 3.35Å
312	I	97.4	Very high	96.1	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-63.4	-39.3	178.6	-64.8	168.3	0	0	0	111.7	I246 L308 L309 T315 A316 F345 N404 V407 F408 L411	I246-I312 HydrophobicContact CG2-CD1 4.06Å; L308-I312 HydrophobicContact CD1-CD1 3.8Å; L308-I312 HydrophobicContact CD1-CG1 4.41Å; L308-I312 HydrophobicContact CG-CD1 3.91Å; L308-I312 VanDerWaalsContact O-CG1 3.31Å; L308-I312 WeakPolarHBondContact O-CG1 3.42Å; L308-I312 PolarHBondContact O-N 3Å; L308-I312 VanDerWaalsContact O-N 3.11Å; L309-I312 PolarHBondContact O-N 3.27Å; I312-T315 PolarHBondContact O-N 3.49Å; I312-A316 PolarHBondContact O-N 2.92Å; I312-F345 HydrophobicContact CD1-CD2 4.45Å; I312-F345 HydrophobicContact CD1-CE2 4.16Å; I312-F345 HydrophobicContact CG1-CD2 3.94Å; I312-F345 HydrophobicContact CG1-CE2 3.97Å; I312-N404 HydrophobicContact CG2-CB 4.15Å; I312-N404 WeakPolarHBondContact CG2-O 3.2Å; I312-V407 HydrophobicContact CD1-CG1 3.93Å; I312-V407 HydrophobicContact CG2-CB 4.34Å; I312-V407 HydrophobicContact CG2-CG1 4.26Å; I312-F408 HydrophobicContact CG2-CB 4.02Å; I312-L411 HydrophobicContact CD1-CD1 3.48Å; I312-L411 VanDerWaalsContact CD1-CD1 3.48Å
313	G	97.6	Very high	96.1	Very high	24 Å²	24	32.2 Å²	32.2	25%	0.247	20%	0.196	C	C	.	.	H	α-helix	trans	-63.9	-42.6	176.5	0	0	0	0	0	112.6	L309 L310 S311 A316 G317 F408	L309-G313 PolarHBondContact O-N 3.16Å; L310-G313 PolarHBondContact O-N 3.48Å; S311-G313 VanDerWaalsContact C-N 3.34Å; S311-G313 PolarHBondContact O-N 3.47Å; G313-A316 PolarHBondContact O-N 2.99Å; G313-G317 PolarHBondContact O-N 2.86Å; G313-G317 VanDerWaalsContact O-N 3.16Å; G313-F408 VanDerWaalsContact CA-CD2 3.49Å
314	I	97.8	Very high	96.2	Very high	46 Å²	46	36.2 Å²	36.2	24%	0.236	20%	0.201	C	C	.	.	H	α-helix	trans	-65.7	-42.6	174.2	-65.6	168.8	0	0	0	110.4	L310 S311 A316 G317 V318 P337 F340	L310-I314 HydrophobicContact CD1-CD1 3.87Å; L310-I314 HydrophobicContact CD1-CG1 4.31Å; L310-I314 HydrophobicContact CG-CD1 3.89Å; L310-I314 VanDerWaalsContact O-CG1 3.3Å; L310-I314 WeakPolarHBondContact O-CG1 3.48Å; L310-I314 PolarHBondContact O-N 3.35Å; S311-I314 PolarHBondContact O-N 3.15Å; I314-A316 VanDerWaalsContact C-N 3.31Å; I314-A316 PolarHBondContact O-N 3.41Å; I314-G317 PolarHBondContact O-N 2.92Å; I314-G317 VanDerWaalsContact O-N 3.14Å; I314-V318 HydrophobicContact CG2-CG2 4.19Å; I314-V318 WeakPolarHBondContact O-CG2 3.43Å; I314-V318 PolarHBondContact O-N 2.97Å; I314-P337 HydrophobicContact CG2-CB 3.82Å; I314-P337 WeakPolarHBondContact CG2-O 3.46Å; I314-F340 HydrophobicContact CD1-CD1 3.78Å; I314-F340 HydrophobicContact CD1-CE1 3.59Å
315	T	97.1	Very high	96.2	Very high	4 Å²	4	34.4 Å²	34.4	3%	0.025	19%	0.193	C	C	.	.	H	α-helix	trans	-58.6	-41.4	176.3	-59.1	0	0	0	0	111.7	S254 S311 I312 V318 G319 S341 E400 N404	S254-T315 WeakPolarHBondContact OG-CG2 3.38Å; S311-T315 WeakPolarHBondContact O-CB 3.45Å; S311-T315 PolarHBondContact O-N 2.71Å; S311-T315 PolarHBondContact O-OG1 3.04Å; I312-T315 PolarHBondContact O-N 3.49Å; T315-V318 PolarHBondContact O-N 3.3Å; T315-G319 PolarHBondContact O-N 2.99Å; T315-S341 WeakPolarHBondContact OG1-CB 3.47Å; T315-S341 PolarHBondContact OG1-OG 3.49Å; T315-E400 HydrophobicContact CG2-CG 4.13Å; T315-E400 VanDerWaalsContact CG2-OE1 3.27Å; T315-E400 WeakPolarHBondContact CG2-OE1 3.25Å; T315-N404 HydrophobicContact CG2-CB 4.46Å
316	A	97.9	Very high	96.1	Very high	3 Å²	3	35.2 Å²	35.2	3%	0.025	20%	0.199	C	C	.	.	H	α-helix	trans	-59.4	-49.6	173.3	0	0	0	0	0	111.3	I312 G313 I314 V318 G319 L320 F401 N404 I405	I312-A316 PolarHBondContact O-N 2.92Å; G313-A316 PolarHBondContact O-N 2.99Å; I314-A316 VanDerWaalsContact C-N 3.31Å; I314-A316 PolarHBondContact O-N 3.41Å; A316-V318 VanDerWaalsContact C-N 3.3Å; A316-V318 PolarHBondContact O-N 3.26Å; A316-G319 PolarHBondContact O-N 3.23Å; A316-G319 VanDerWaalsContact O-N 3.15Å; A316-L320 PolarHBondContact O-N 3.34Å; A316-F401 HydrophobicContact CB-CD2 4.25Å; A316-F401 WeakPolarHBondContact O-CD2 3.48Å; A316-N404 HydrophobicContact CB-CB 3.81Å; A316-I405 HydrophobicContact CB-CB 4.44Å
317	G	97.6	Very high	96.1	Very high	41 Å²	41	35.2 Å²	35.2	42%	0.423	20%	0.196	S	C	.	.	H	α-helix	trans	-59.8	-38.1	176.9	0	0	0	0	0	113.5	G313 I314 L320 A321	G313-G317 PolarHBondContact O-N 2.86Å; G313-G317 VanDerWaalsContact O-N 3.16Å; I314-G317 PolarHBondContact O-N 2.92Å; I314-G317 VanDerWaalsContact O-N 3.14Å; G317-L320 PolarHBondContact O-N 3.23Å; G317-A321 WeakPolarHBondContact O-CB 3.4Å; G317-A321 PolarHBondContact O-N 3.15Å
318	V	97.1	Very high	95.9	Very high	5 Å²	5	37.3 Å²	37.3	3%	0.03	21%	0.209	C	C	.	.	H	α-helix	trans	-62.2	-46.4	173.4	166	0	0	0	0	111	I314 T315 A316 L320 A321 Q322 P337 W338	I314-V318 HydrophobicContact CG2-CG2 4.19Å; I314-V318 WeakPolarHBondContact O-CG2 3.43Å; I314-V318 PolarHBondContact O-N 2.97Å; T315-V318 PolarHBondContact O-N 3.3Å; A316-V318 VanDerWaalsContact C-N 3.3Å; A316-V318 PolarHBondContact O-N 3.26Å; V318-L320 VanDerWaalsContact C-N 3.29Å; V318-L320 PolarHBondContact O-N 2.97Å; V318-A321 PolarHBondContact O-N 3.36Å; V318-A321 VanDerWaalsContact O-N 3.14Å; V318-Q322 HydrophobicContact CG1-CG 4.24Å; V318-Q322 WeakPolarHBondContact O-CB 3.39Å; V318-Q322 VanDerWaalsContact O-CG 3.32Å; V318-Q322 WeakPolarHBondContact O-CG 3.37Å; V318-Q322 PolarHBondContact O-N 3.45Å; V318-P337 HydrophobicContact CG2-CB 3.96Å; V318-P337 HydrophobicContact CG2-CG 4.16Å; V318-W338 HydrophobicContact CG1-CB 3.7Å; V318-W338 HydrophobicContact CG1-CG 3.91Å; V318-W338 HydrophobicContact CG2-CB 4.19Å
319	G	96.8	Very high	95.7	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57.4	-42.7	176.1	0	0	0	0	0	112.3	T315 A316 Q322 A323 G397	T315-G319 PolarHBondContact O-N 2.99Å; A316-G319 PolarHBondContact O-N 3.23Å; A316-G319 VanDerWaalsContact O-N 3.15Å; G319-Q322 PolarHBondContact O-N 3.06Å; G319-A323 WeakPolarHBondContact O-CB 3.27Å; G319-A323 PolarHBondContact O-N 3.4Å; G319-G397 CarbonylContact C-O 3.58Å; G319-G397 WeakPolarHBondContact CA-O 3.42Å; G319-G397 CarbonylContact O-C 3.59Å; G319-G397 WeakPolarHBondContact O-CA 3.09Å
320	L	96.9	Very high	95.6	Very high	67 Å²	67	46.2 Å²	46.2	35%	0.351	25%	0.248	S	C	.	.	H	α-helix	trans	-63.9	-44.5	175.3	-170	65.9	0	0	0	111.7	A316 G317 V318 Q322 A323 Y324 F401	A316-L320 PolarHBondContact O-N 3.34Å; G317-L320 PolarHBondContact O-N 3.23Å; V318-L320 VanDerWaalsContact C-N 3.29Å; V318-L320 PolarHBondContact O-N 2.97Å; L320-Q322 VanDerWaalsContact C-N 3.33Å; L320-Q322 PolarHBondContact O-N 3.36Å; L320-A323 WeakPolarHBondContact O-CB 3.48Å; L320-A323 PolarHBondContact O-N 3.47Å; L320-Y324 HydrophobicContact CD1-CD2 4.16Å; L320-Y324 HydrophobicContact CD1-CE2 3.76Å; L320-Y324 HydrophobicContact CG-CD2 4.45Å; L320-Y324 HydrophobicContact CG-CE2 4.48Å; L320-Y324 WeakPolarHBondContact O-CD2 3.37Å; L320-Y324 PolarHBondContact O-N 2.99Å; L320-F401 HydrophobicContact CB-CB 4.42Å; L320-F401 HydrophobicContact CB-CD2 3.84Å; L320-F401 HydrophobicContact CB-CE2 4.39Å; L320-F401 HydrophobicContact CB-CG 4.23Å; L320-F401 HydrophobicContact CD1-CD1 4.48Å; L320-F401 HydrophobicContact CD1-CD2 4.44Å; L320-F401 HydrophobicContact CD1-CG 4.34Å; L320-F401 HydrophobicContact CD2-CE2 4.32Å
321	A	96.5	Very high	95.4	Very high	42 Å²	42	42.3 Å²	42.3	35%	0.347	23%	0.228	S	C	.	.	H	α-helix	trans	-64.4	-37.2	177.7	0	0	0	0	0	112.5	G317 V318 M325 T334	G317-A321 WeakPolarHBondContact O-CB 3.4Å; G317-A321 PolarHBondContact O-N 3.15Å; V318-A321 PolarHBondContact O-N 3.36Å; V318-A321 VanDerWaalsContact O-N 3.14Å; A321-M325 PolarHBondContact O-N 3Å; A321-M325 VanDerWaalsContact O-N 3.15Å; A321-T334 HydrophobicContact CB-CG2 3.51Å
322	Q	95.2	Very high	95.2	Very high	1 Å²	1	44.2 Å²	44.2	1%	0.005	24%	0.24	C	C	.	.	H	α-helix	trans	-66.7	-36.2	173.8	-74.2	170.2	-19.9	0	0	112.1	F257 V318 G319 L320 Y324 M325 E400	F257-Q322 HydrophobicContact CD2-CG 4.37Å; F257-Q322 HydrophobicContact CE2-CB 4.05Å; F257-Q322 HydrophobicContact CE2-CG 3.84Å; F257-Q322 HydrophobicContact CZ-CG 3.99Å; V318-Q322 HydrophobicContact CG1-CG 4.24Å; V318-Q322 WeakPolarHBondContact O-CB 3.39Å; V318-Q322 VanDerWaalsContact O-CG 3.32Å; V318-Q322 WeakPolarHBondContact O-CG 3.37Å; V318-Q322 PolarHBondContact O-N 3.45Å; G319-Q322 PolarHBondContact O-N 3.06Å; L320-Q322 VanDerWaalsContact C-N 3.33Å; L320-Q322 PolarHBondContact O-N 3.36Å; Q322-Y324 VanDerWaalsContact C-N 3.3Å; Q322-Y324 PolarHBondContact O-N 2.8Å; Q322-M325 WeakPolarHBondContact O-CB 3.15Å; Q322-M325 PolarHBondContact O-N 3.12Å; Q322-E400 PolarHBondContact OE1-OE2 3.4Å; Q322-E400 VanDerWaalsContact OE1-OE2 3.04Å
323	A	95.3	Very high	94.9	Very high	12 Å²	12	49.2 Å²	49.2	10%	0.099	27%	0.267	C	S	.	.	H	α-helix	trans	-63	-36.5	178.5	0	0	0	0	0	112.9	G319 L320 A394 L398	G319-A323 WeakPolarHBondContact O-CB 3.27Å; G319-A323 PolarHBondContact O-N 3.4Å; L320-A323 WeakPolarHBondContact O-CB 3.48Å; L320-A323 PolarHBondContact O-N 3.47Å; A323-A394 WeakPolarHBondContact O-CB 3.39Å; A323-L398 HydrophobicContact CB-CD2 3.92Å; A323-L398 HydrophobicContact CB-CG 3.84Å
324	Y	94.6	Very high	94.8	Very high	165 Å²	165	48.7 Å²	48.7	65%	0.647	26%	0.258	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.4	17	178.8	-66.3	-78.3	0	0	0	113.1	L320 Q322 Q326	L320-Y324 HydrophobicContact CD1-CD2 4.16Å; L320-Y324 HydrophobicContact CD1-CE2 3.76Å; L320-Y324 HydrophobicContact CG-CD2 4.45Å; L320-Y324 HydrophobicContact CG-CE2 4.48Å; L320-Y324 WeakPolarHBondContact O-CD2 3.37Å; L320-Y324 PolarHBondContact O-N 2.99Å; Q322-Y324 VanDerWaalsContact C-N 3.3Å; Q322-Y324 PolarHBondContact O-N 2.8Å; Y324-Q326 PolarHBondContact O-N 3.26Å
325	M	93.5	Very high	94.5	Very high	5 Å²	5	46.5 Å²	46.5	3%	0.025	25%	0.247	C	C	.	.			trans	-71.9	126.7	180	-170.6	172.5	61.7	0	0	110.4	F257 F268 F269 A321 Q322 H330 L331 L393	F257-M325 HydrophobicContact CE2-CE 4.33Å; F257-M325 HydrophobicContact CZ-CE 4.01Å; F268-M325 WeakPolarHBondContact CE1-O 3.4Å; F268-M325 VanDerWaalsContact CZ-O 3.23Å; F268-M325 WeakPolarHBondContact CZ-O 3.38Å; F269-M325 HydrophobicContact CE1-CG 4.4Å; F269-M325 HydrophobicContact CE2-CE 3.65Å; F269-M325 HydrophobicContact CE2-SD 4.29Å; F269-M325 HydrophobicContact CZ-CE 3.39Å; F269-M325 HydrophobicContact CZ-CG 3.84Å; F269-M325 HydrophobicContact CZ-SD 3.64Å; A321-M325 PolarHBondContact O-N 3Å; A321-M325 VanDerWaalsContact O-N 3.15Å; Q322-M325 WeakPolarHBondContact O-CB 3.15Å; Q322-M325 PolarHBondContact O-N 3.12Å; M325-H330 HydrophobicContact CG-CB 3.92Å; M325-L331 HydrophobicContact CE-CD1 4.24Å; M325-L331 VanDerWaalsContact SD-CA 3.59Å; M325-L331 HydrophobicContact SD-CB 3.57Å; M325-L331 VanDerWaalsContact SD-CB 3.57Å; M325-L331 HydrophobicContact SD-CD1 3.68Å; M325-L331 HydrophobicContact SD-CG 4.21Å; M325-L393 HydrophobicContact CE-CD2 3.68Å
326	Q	90.9	Very high	94.3	Very high	152 Å²	152	49.4 Å²	49.4	71%	0.71	27%	0.265	S	S	*	.			trans	-121.9	-27.5	-178.7	-67.1	-178.2	-17.5	0	0	112.9	Y324	Y324-Q326 PolarHBondContact O-N 3.26Å
327	T	93.3	Very high	94.2	Very high	59 Å²	59	51.5 Å²	51.5	36%	0.362	28%	0.278	S	S	.	.	S	Bend	trans	-128.1	156.9	-173	66.8	0	0	0	0	111.2	F269 F329 H330 L331	F269-T327 WeakPolarHBondContact CE1-O 3.38Å; T327-F329 PolarHBondContact O-N 2.96Å; T327-H330 WeakPolarHBondContact O-CB 3.45Å; T327-H330 PolarHBondContact O-N 3.19Å; T327-H330 VanDerWaalsContact O-N 3.12Å; T327-H330 PolarHBondContact OG1-CD2 2.98Å; T327-H330 VanDerWaalsContact OG1-CD2 3.28Å; T327-H330 PolarHBondContact OG1-N 3.04Å; T327-L331 PolarHBondContact O-N 3.19Å; T327-L331 VanDerWaalsContact O-N 3.16Å
328	V	92.5	Very high	94.1	Very high	48 Å²	48	49.5 Å²	49.5	29%	0.291	26%	0.258	S	S	.	.	H	α-helix	trans	-59.9	-29.6	172.4	-176.5	0	0	0	0	110.9	F269 L271 L279 L331 C332	F269-V328 HydrophobicContact CB-CG2 4.26Å; F269-V328 HydrophobicContact CD1-CG2 3.87Å; F269-V328 HydrophobicContact CE1-CG2 4.47Å; F269-V328 HydrophobicContact CG-CG2 4.2Å; L271-V328 HydrophobicContact CD1-CG2 4.37Å; L271-V328 HydrophobicContact CD2-CG2 3.91Å; L279-V328 HydrophobicContact CD1-CG1 4.18Å; L279-V328 HydrophobicContact CD2-CG1 4.16Å; V328-L331 WeakPolarHBondContact O-CB 3.34Å; V328-L331 PolarHBondContact O-N 3.32Å; V328-C332 PolarHBondContact O-N 2.96Å; V328-C332 PolarHBondContact O-SG 3.46Å; V328-C332 VanDerWaalsContact O-SG 3.32Å
329	F	92.6	Very high	93.9	Very high	141 Å²	141	49.6 Å²	49.6	62%	0.618	26%	0.258	S	S	*	.	H	α-helix	trans	-63.7	-45.2	174.8	-178.3	-104.9	0	0	0	112	T327 L331 C332 L333	T327-F329 PolarHBondContact O-N 2.96Å; F329-L331 VanDerWaalsContact C-N 3.28Å; F329-L331 PolarHBondContact O-N 2.84Å; F329-C332 PolarHBondContact O-N 3.44Å; F329-L333 HydrophobicContact CD1-CD1 4.14Å; F329-L333 HydrophobicContact CE1-CD1 3.54Å; F329-L333 HydrophobicContact CE1-CG 4.24Å; F329-L333 HydrophobicContact CZ-CD1 3.88Å; F329-L333 HydrophobicContact CZ-CD2 4.42Å; F329-L333 HydrophobicContact CZ-CG 4.22Å; F329-L333 PolarHBondContact O-N 3.45Å; F329-L333 VanDerWaalsContact O-N 3.1Å
330	H	93.2	Very high	93.7	Very high	74 Å²	74	51 Å²	51	34%	0.343	26%	0.264	S	S	.	.	H	α-helix	trans	-59	-43	173.5	-65.5	-178.8	0	0	0	110.6	M325 T327 C332 L333 T334	M325-H330 HydrophobicContact CG-CB 3.92Å; T327-H330 WeakPolarHBondContact O-CB 3.45Å; T327-H330 PolarHBondContact O-N 3.19Å; T327-H330 VanDerWaalsContact O-N 3.12Å; T327-H330 PolarHBondContact OG1-CD2 2.98Å; T327-H330 VanDerWaalsContact OG1-CD2 3.28Å; T327-H330 PolarHBondContact OG1-N 3.04Å; H330-C332 PolarHBondContact O-N 2.97Å; H330-L333 PolarHBondContact O-N 3.38Å; H330-T334 WeakPolarHBondContact O-CG2 3.35Å; H330-T334 PolarHBondContact O-N 2.89Å; H330-T334 PolarHBondContact O-OG1 3.15Å
331	L	92.1	Very high	93.7	Very high	0 Å²	0	47.8 Å²	47.8	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-56.2	-53.7	174.9	177.5	67	0	0	0	111.1	F261 F269 L279 M325 T327 V328 F329 L333 T334 V335	F261-L331 HydrophobicContact CE2-CD1 4.18Å; F261-L331 HydrophobicContact CE2-CD2 3.65Å; F261-L331 HydrophobicContact CZ-CD2 4.08Å; F269-L331 HydrophobicContact CD2-CD2 4.46Å; F269-L331 HydrophobicContact CE2-CB 4.41Å; F269-L331 HydrophobicContact CE2-CD2 3.89Å; F269-L331 HydrophobicContact CZ-CB 4.03Å; F269-L331 HydrophobicContact CZ-CD2 4.31Å; L279-L331 HydrophobicContact CD1-CD2 3.88Å; L279-L331 HydrophobicContact CD2-CD2 4.48Å; M325-L331 HydrophobicContact CE-CD1 4.24Å; M325-L331 VanDerWaalsContact SD-CA 3.59Å; M325-L331 HydrophobicContact SD-CB 3.57Å; M325-L331 VanDerWaalsContact SD-CB 3.57Å; M325-L331 HydrophobicContact SD-CD1 3.68Å; M325-L331 HydrophobicContact SD-CG 4.21Å; T327-L331 PolarHBondContact O-N 3.19Å; T327-L331 VanDerWaalsContact O-N 3.16Å; V328-L331 WeakPolarHBondContact O-CB 3.34Å; V328-L331 PolarHBondContact O-N 3.32Å; F329-L331 VanDerWaalsContact C-N 3.28Å; F329-L331 PolarHBondContact O-N 2.84Å; L331-L333 VanDerWaalsContact C-N 3.25Å; L331-L333 PolarHBondContact O-N 2.89Å; L331-T334 WeakPolarHBondContact CA-OG1 3.44Å; L331-T334 PolarHBondContact O-N 3.38Å; L331-T334 PolarHBondContact O-OG1 3.23Å; L331-V335 HydrophobicContact CD1-CG2 4.2Å; L331-V335 HydrophobicContact CG-CG2 4.25Å; L331-V335 VanDerWaalsContact O-CG2 3.24Å; L331-V335 WeakPolarHBondContact O-CG2 3.43Å; L331-V335 PolarHBondContact O-N 3.36Å
332	C	92.6	Very high	93.5	Very high	39 Å²	39	46.7 Å²	46.7	26%	0.264	24%	0.236	S	C	.	.	H	α-helix	trans	-55.6	-39.6	-179.5	-69.5	0	0	0	0	112.8	Y282 V328 F329 H330	Y282-C332 HydrophobicContact CE1-CB 4.38Å; Y282-C332 PolarHBondContact OH-O 2.9Å; V328-C332 PolarHBondContact O-N 2.96Å; V328-C332 PolarHBondContact O-SG 3.46Å; V328-C332 VanDerWaalsContact O-SG 3.32Å; F329-C332 PolarHBondContact O-N 3.44Å; H330-C332 PolarHBondContact O-N 2.97Å
333	L	92.9	Very high	93.3	Very high	106 Å²	106	46.9 Å²	46.9	56%	0.555	24%	0.237	S	C	*	.	H	α-helix	trans	-65.9	-38.3	174.9	-68.8	179.4	0	0	0	112.7	F329 H330 L331 P337	F329-L333 HydrophobicContact CD1-CD1 4.14Å; F329-L333 HydrophobicContact CE1-CD1 3.54Å; F329-L333 HydrophobicContact CE1-CG 4.24Å; F329-L333 HydrophobicContact CZ-CD1 3.88Å; F329-L333 HydrophobicContact CZ-CD2 4.42Å; F329-L333 HydrophobicContact CZ-CG 4.22Å; F329-L333 PolarHBondContact O-N 3.45Å; F329-L333 VanDerWaalsContact O-N 3.1Å; H330-L333 PolarHBondContact O-N 3.38Å; L331-L333 VanDerWaalsContact C-N 3.25Å; L331-L333 PolarHBondContact O-N 2.89Å; L333-P337 WeakPolarHBondContact O-CD 3.39Å
334	T	93.8	Very high	93.3	Very high	12 Å²	12	46.4 Å²	46.4	7%	0.074	23%	0.233	C	C	.	.	H	α-helix	trans	-75.3	-25.1	-179.5	60.2	0	0	0	0	114.2	A321 H330 L331 T336 P337 W338	A321-T334 HydrophobicContact CB-CG2 3.51Å; H330-T334 WeakPolarHBondContact O-CG2 3.35Å; H330-T334 PolarHBondContact O-N 2.89Å; H330-T334 PolarHBondContact O-OG1 3.15Å; L331-T334 WeakPolarHBondContact CA-OG1 3.44Å; L331-T334 PolarHBondContact O-N 3.38Å; L331-T334 PolarHBondContact O-OG1 3.23Å; T334-T336 PolarHBondContact O-N 3.04Å; T334-P337 VanDerWaalsContact O-CD 3.25Å; T334-P337 WeakPolarHBondContact O-CD 3.4Å; T334-P337 VanDerWaalsContact O-CG 3.29Å; T334-P337 WeakPolarHBondContact O-CG 3.4Å; T334-W338 WeakPolarHBondContact O-CB 3.46Å; T334-W338 PolarHBondContact O-N 2.72Å
335	V	93.1	Very high	93.3	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-61.8	-41.3	-176.2	167.2	0	0	0	0	112.6	Y282 F283 V286 L331 W338 M339	Y282-V335 HydrophobicContact CD1-CB 4.44Å; Y282-V335 HydrophobicContact CD1-CG1 4.02Å; Y282-V335 HydrophobicContact CE1-CB 3.74Å; Y282-V335 HydrophobicContact CE1-CG1 3.6Å; Y282-V335 HydrophobicContact CE1-CG2 4.2Å; F283-V335 HydrophobicContact CD1-CB 4.38Å; F283-V335 HydrophobicContact CD1-CG1 3.58Å; F283-V335 HydrophobicContact CD1-CG2 3.82Å; F283-V335 HydrophobicContact CE1-CB 4.17Å; F283-V335 HydrophobicContact CE1-CG1 3.86Å; F283-V335 HydrophobicContact CE1-CG2 3.16Å; F283-V335 HydrophobicContact CG-CG1 4.24Å; F283-V335 HydrophobicContact CZ-CG2 3.68Å; V286-V335 HydrophobicContact CB-CG1 4.49Å; V286-V335 HydrophobicContact CG2-CG1 4.33Å; L331-V335 HydrophobicContact CD1-CG2 4.2Å; L331-V335 HydrophobicContact CG-CG2 4.25Å; L331-V335 VanDerWaalsContact O-CG2 3.24Å; L331-V335 WeakPolarHBondContact O-CG2 3.43Å; L331-V335 PolarHBondContact O-N 3.36Å; V335-W338 PolarHBondContact O-N 3.37Å; V335-M339 HydrophobicContact CG1-CG 4.17Å; V335-M339 WeakPolarHBondContact O-CB 3.39Å; V335-M339 WeakPolarHBondContact O-CG 3.19Å; V335-M339 PolarHBondContact O-N 3.31Å
336	T	92.8	Very high	93.3	Very high	66 Å²	66	40 Å²	40	41%	0.405	21%	0.21	S	C	.	.	H	α-helix	trans	-62.2	-55.9	-179.5	-60	0	0	0	0	112.5	Y282 T334 W338 M339 F340	Y282-T336 PolarHBondContact OH-OG1 3.31Å; T334-T336 PolarHBondContact O-N 3.04Å; T336-W338 VanDerWaalsContact C-N 3.28Å; T336-W338 PolarHBondContact O-N 3.11Å; T336-M339 PolarHBondContact O-N 2.79Å; T336-F340 VanDerWaalsContact O-CB 3.27Å; T336-F340 WeakPolarHBondContact O-CB 3.44Å; T336-F340 PolarHBondContact O-N 2.9Å
337	P	95.8	Very high	93.4	Very high	46 Å²	46	35.5 Å²	35.5	30%	0.299	19%	0.193	S	C	.	.	H	α-helix	trans	-64.6	-30.8	175.8	23.4	-31.8	0	0	0	112.9	I314 V318 L333 T334 S341	I314-P337 HydrophobicContact CG2-CB 3.82Å; I314-P337 WeakPolarHBondContact CG2-O 3.46Å; V318-P337 HydrophobicContact CG2-CB 3.96Å; V318-P337 HydrophobicContact CG2-CG 4.16Å; L333-P337 WeakPolarHBondContact O-CD 3.39Å; T334-P337 VanDerWaalsContact O-CD 3.25Å; T334-P337 WeakPolarHBondContact O-CD 3.4Å; T334-P337 VanDerWaalsContact O-CG 3.29Å; T334-P337 WeakPolarHBondContact O-CG 3.4Å; P337-S341 VanDerWaalsContact O-CB 3.3Å; P337-S341 WeakPolarHBondContact O-CB 3.49Å; P337-S341 PolarHBondContact O-N 3.49Å; P337-S341 PolarHBondContact O-OG 2.7Å
338	W	94.4	Very high	93.4	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-65.2	-53.5	175.2	-179.6	36.3	0	0	0	112.4	F257 Q258 F283 V318 T334 V335 T336 F340 S341 L342	F257-W338 AromaticContact CD1-CH2 3.48Å; F257-W338 HydrophobicContact CD1-CH2 3.48Å; F257-W338 VanDerWaalsContact CD1-CH2 3.48Å; F257-W338 AromaticContact CD1-CZ2 3.67Å; F257-W338 HydrophobicContact CD1-CZ2 3.67Å; F257-W338 AromaticContact CD1-CZ3 3.96Å; F257-W338 HydrophobicContact CD1-CZ3 3.96Å; F257-W338 HydrophobicContact CE1-CE3 4.5Å; F257-W338 AromaticContact CE1-CH2 3.9Å; F257-W338 HydrophobicContact CE1-CH2 3.9Å; F257-W338 HydrophobicContact CE1-CZ2 4.43Å; F257-W338 AromaticContact CE1-CZ3 3.91Å; F257-W338 HydrophobicContact CE1-CZ3 3.91Å; Q258-W338 HydrophobicContact CB-CH2 4.12Å; Q258-W338 HydrophobicContact CB-CZ2 3.79Å; Q258-W338 HydrophobicContact CG-CH2 4.3Å; Q258-W338 HydrophobicContact CG-CZ2 4.26Å; F283-W338 HydrophobicContact CD2-CZ3 4.21Å; F283-W338 HydrophobicContact CE2-CE3 4.46Å; F283-W338 HydrophobicContact CE2-CH2 4.12Å; F283-W338 AromaticContact CE2-CZ3 3.47Å; F283-W338 HydrophobicContact CE2-CZ3 3.47Å; F283-W338 VanDerWaalsContact CE2-CZ3 3.47Å; F283-W338 AromaticContact CZ-CZ3 3.89Å; F283-W338 HydrophobicContact CZ-CZ3 3.89Å; V318-W338 HydrophobicContact CG1-CB 3.7Å; V318-W338 HydrophobicContact CG1-CG 3.91Å; V318-W338 HydrophobicContact CG2-CB 4.19Å; T334-W338 WeakPolarHBondContact O-CB 3.46Å; T334-W338 PolarHBondContact O-N 2.72Å; V335-W338 PolarHBondContact O-N 3.37Å; T336-W338 VanDerWaalsContact C-N 3.28Å; T336-W338 PolarHBondContact O-N 3.11Å; W338-F340 VanDerWaalsContact C-N 3.28Å; W338-F340 PolarHBondContact O-N 3.02Å; W338-S341 PolarHBondContact O-N 3.43Å; W338-S341 PolarHBondContact O-OG 2.74Å; W338-L342 VanDerWaalsContact O-CB 3.23Å; W338-L342 WeakPolarHBondContact O-CB 3.41Å; W338-L342 PolarHBondContact O-N 2.98Å
339	M	92.9	Very high	93.6	Very high	6 Å²	6	30.5 Å²	30.5	3%	0.03	16%	0.162	C	C	.	.	H	α-helix	trans	-63.5	-35.9	178	-71.1	-60.1	104.1	0	0	112.1	V286 Q287 V335 T336 L342 S343	V286-M339 HydrophobicContact CG1-CB 3.71Å; V286-M339 HydrophobicContact CG1-CG 4.01Å; Q287-M339 HydrophobicContact CB-SD 4.46Å; V335-M339 HydrophobicContact CG1-CG 4.17Å; V335-M339 WeakPolarHBondContact O-CB 3.39Å; V335-M339 WeakPolarHBondContact O-CG 3.19Å; V335-M339 PolarHBondContact O-N 3.31Å; T336-M339 PolarHBondContact O-N 2.79Å; M339-L342 HydrophobicContact CE-CD2 4.21Å; M339-S343 WeakPolarHBondContact O-CB 3.41Å; M339-S343 PolarHBondContact O-N 3.43Å; M339-S343 PolarHBondContact O-OG 2.95Å
340	F	94.1	Very high	93.6	Very high	30 Å²	30	25.7 Å²	25.7	13%	0.132	14%	0.143	C	C	.	.	H	α-helix	trans	-60.8	-57.8	173.2	176	-99.8	0	0	0	112	V290 L294 L298 L310 I314 T336 W338 L342 S343 V344	V290-F340 HydrophobicContact CG1-CD2 4.27Å; V290-F340 HydrophobicContact CG2-CB 4.39Å; L294-F340 HydrophobicContact CD2-CD2 3.66Å; L294-F340 HydrophobicContact CD2-CE2 3.5Å; L294-F340 VanDerWaalsContact CD2-CE2 3.5Å; L294-F340 HydrophobicContact CG-CE2 4.19Å; L298-F340 HydrophobicContact CD2-CE2 3.51Å; L298-F340 HydrophobicContact CD2-CZ 3.46Å; L298-F340 VanDerWaalsContact CD2-CZ 3.46Å; L310-F340 HydrophobicContact CD2-CE1 4.49Å; I314-F340 HydrophobicContact CD1-CD1 3.78Å; I314-F340 HydrophobicContact CD1-CE1 3.59Å; T336-F340 VanDerWaalsContact O-CB 3.27Å; T336-F340 WeakPolarHBondContact O-CB 3.44Å; T336-F340 PolarHBondContact O-N 2.9Å; W338-F340 VanDerWaalsContact C-N 3.28Å; W338-F340 PolarHBondContact O-N 3.02Å; F340-L342 PolarHBondContact O-N 3.06Å; F340-S343 PolarHBondContact O-N 3.28Å; F340-V344 HydrophobicContact CD2-CG2 4.28Å; F340-V344 HydrophobicContact CE1-CG2 4.33Å; F340-V344 HydrophobicContact CE2-CG2 3.9Å; F340-V344 HydrophobicContact CZ-CG2 3.94Å; F340-V344 WeakPolarHBondContact O-CG2 3.35Å; F340-V344 PolarHBondContact O-N 3.22Å
341	S	95.6	Very high	93.6	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.5	-45.3	-177.9	56.5	0	0	0	0	111.9	S311 T315 P337 W338 S343 V344 F345	S311-S341 WeakPolarHBondContact CB-O 3.33Å; S311-S341 WeakPolarHBondContact O-CB 3.35Å; T315-S341 WeakPolarHBondContact OG1-CB 3.47Å; T315-S341 PolarHBondContact OG1-OG 3.49Å; P337-S341 VanDerWaalsContact O-CB 3.3Å; P337-S341 WeakPolarHBondContact O-CB 3.49Å; P337-S341 PolarHBondContact O-N 3.49Å; P337-S341 PolarHBondContact O-OG 2.7Å; W338-S341 PolarHBondContact O-N 3.43Å; W338-S341 PolarHBondContact O-OG 2.74Å; S341-S343 PolarHBondContact O-N 3.16Å; S341-V344 PolarHBondContact O-N 3Å; S341-F345 WeakPolarHBondContact O-CB 3.31Å; S341-F345 PolarHBondContact O-N 3.47Å
342	L	93.1	Very high	93.7	Very high	18 Å²	18	24.8 Å²	24.8	9%	0.094	14%	0.143	C	C	.	.	H	α-helix	trans	-62.1	-41	178.2	-175.9	63.2	0	0	0	112.4	W338 M339 F340 N346	W338-L342 VanDerWaalsContact O-CB 3.23Å; W338-L342 WeakPolarHBondContact O-CB 3.41Å; W338-L342 PolarHBondContact O-N 2.98Å; M339-L342 HydrophobicContact CE-CD2 4.21Å; F340-L342 PolarHBondContact O-N 3.06Å; L342-N346 WeakPolarHBondContact O-CB 3.49Å; L342-N346 PolarHBondContact O-N 3.24Å; L342-N346 PolarHBondContact O-ND2 2.98Å
343	S	91.6	Very high	93.8	Very high	5 Å²	5	23 Å²	23	4%	0.035	13%	0.13	C	C	.	.	H	α-helix	trans	-68.3	-48.7	179	-63	0	0	0	0	111.3	Q291 I295 M339 F340 S341 F345 N346 V347	Q291-S343 PolarHBondContact NE2-OG 3.4Å; I295-S343 WeakPolarHBondContact CD1-O 3.38Å; M339-S343 WeakPolarHBondContact O-CB 3.41Å; M339-S343 PolarHBondContact O-N 3.43Å; M339-S343 PolarHBondContact O-OG 2.95Å; F340-S343 PolarHBondContact O-N 3.28Å; S341-S343 PolarHBondContact O-N 3.16Å; S343-F345 VanDerWaalsContact C-N 3.34Å; S343-F345 PolarHBondContact O-N 3.45Å; S343-N346 PolarHBondContact O-N 2.97Å; S343-V347 WeakPolarHBondContact O-CG2 3.35Å; S343-V347 PolarHBondContact O-N 3.28Å
344	V	94.1	Very high	93.7	Very high	2 Å²	2	19.3 Å²	19.3	1%	0.012	11%	0.112	C	C	.	.	H	α-helix	trans	-60.4	-45.1	177.5	173.8	0	0	0	0	110.5	I295 L298 L307 F340 S341 N346 V347 I348	I295-V344 HydrophobicContact CD1-CG2 4.33Å; I295-V344 HydrophobicContact CG1-CG2 4.48Å; L298-V344 HydrophobicContact CD2-CG2 4.47Å; L307-V344 HydrophobicContact CB-CG1 4.09Å; F340-V344 HydrophobicContact CD2-CG2 4.28Å; F340-V344 HydrophobicContact CE1-CG2 4.33Å; F340-V344 HydrophobicContact CE2-CG2 3.9Å; F340-V344 HydrophobicContact CZ-CG2 3.94Å; F340-V344 WeakPolarHBondContact O-CG2 3.35Å; F340-V344 PolarHBondContact O-N 3.22Å; S341-V344 PolarHBondContact O-N 3Å; V344-N346 PolarHBondContact O-N 3.41Å; V344-V347 PolarHBondContact O-N 2.95Å; V344-I348 HydrophobicContact CG1-CG1 4.03Å; V344-I348 VanDerWaalsContact O-CB 3.3Å; V344-I348 WeakPolarHBondContact O-CB 3.23Å; V344-I348 WeakPolarHBondContact O-CG1 3.22Å; V344-I348 PolarHBondContact O-N 2.89Å
345	F	95.4	Very high	93.7	Very high	5 Å²	5	25.3 Å²	25.3	2%	0.022	14%	0.138	C	C	.	.	H	α-helix	trans	-57.5	-48.9	177.9	177	-101.3	0	0	0	112.2	I246 K247 A250 L308 I312 S341 S343 T349	I246-F345 HydrophobicContact CG2-CE2 4.27Å; K247-F345 HydrophobicContact CG-CE1 4.35Å; A250-F345 HydrophobicContact CB-CE2 3.84Å; A250-F345 HydrophobicContact CB-CZ 3.78Å; L308-F345 HydrophobicContact CD1-CD2 3.99Å; L308-F345 HydrophobicContact CD1-CE2 4.16Å; I312-F345 HydrophobicContact CD1-CD2 4.45Å; I312-F345 HydrophobicContact CD1-CE2 4.16Å; I312-F345 HydrophobicContact CG1-CD2 3.94Å; I312-F345 HydrophobicContact CG1-CE2 3.97Å; S341-F345 WeakPolarHBondContact O-CB 3.31Å; S341-F345 PolarHBondContact O-N 3.47Å; S343-F345 VanDerWaalsContact C-N 3.34Å; S343-F345 PolarHBondContact O-N 3.45Å; F345-T349 HydrophobicContact CD2-CG2 4.18Å; F345-T349 HydrophobicContact CE1-CG2 4.48Å; F345-T349 HydrophobicContact CE2-CG2 3.96Å; F345-T349 HydrophobicContact CZ-CG2 4.15Å; F345-T349 WeakPolarHBondContact O-CB 3.43Å; F345-T349 VanDerWaalsContact O-CG2 3.28Å; F345-T349 WeakPolarHBondContact O-CG2 3.37Å; F345-T349 PolarHBondContact O-N 3.17Å; F345-T349 PolarHBondContact O-OG1 3.49Å
346	N	93	Very high	93.7	Very high	30 Å²	30	28.1 Å²	28.1	16%	0.16	15%	0.152	C	C	.	.	H	α-helix	trans	-63.5	-48.4	180	-81	-59.3	0	0	0	112	L342 S343 V344 I348 T349 D350 Q373	L342-N346 WeakPolarHBondContact O-CB 3.49Å; L342-N346 PolarHBondContact O-N 3.24Å; L342-N346 PolarHBondContact O-ND2 2.98Å; S343-N346 PolarHBondContact O-N 2.97Å; V344-N346 PolarHBondContact O-N 3.41Å; N346-I348 PolarHBondContact O-N 3.2Å; N346-T349 PolarHBondContact O-OG1 3.19Å; N346-T349 VanDerWaalsContact O-OG1 3.07Å; N346-D350 WeakPolarHBondContact O-CB 3.48Å; N346-D350 VanDerWaalsContact O-CG 3.22Å; N346-D350 PolarHBondContact O-N 3.1Å; N346-Q373 PolarHBondContact OD1-NE2 2.88Å
347	V	92	Very high	93.6	Very high	58 Å²	58	25.4 Å²	25.4	35%	0.352	14%	0.135	S	C	.	.	H	α-helix	trans	-63.4	-44.2	-179.1	171.1	0	0	0	0	111.8	I295 T299 S343 V344 S351	I295-V347 HydrophobicContact CD1-CB 3.91Å; I295-V347 HydrophobicContact CD1-CG1 4.47Å; I295-V347 HydrophobicContact CD1-CG2 3.48Å; I295-V347 VanDerWaalsContact CD1-CG2 3.48Å; I295-V347 HydrophobicContact CG1-CB 4.33Å; I295-V347 HydrophobicContact CG1-CG1 4.38Å; I295-V347 HydrophobicContact CG1-CG2 4.19Å; T299-V347 HydrophobicContact CG2-CG1 4.13Å; S343-V347 WeakPolarHBondContact O-CG2 3.35Å; S343-V347 PolarHBondContact O-N 3.28Å; V344-V347 PolarHBondContact O-N 2.95Å; V347-S351 VanDerWaalsContact O-CB 3.3Å; V347-S351 WeakPolarHBondContact O-CB 3.33Å; V347-S351 PolarHBondContact O-N 3.21Å
348	I	94.8	Very high	93.4	Very high	2 Å²	2	25.8 Å²	25.8	1%	0.01	14%	0.138	C	C	.	.	H	α-helix	trans	-69.7	-43	-178.4	-67	-62.4	0	0	0	111.5	T299 E304 L307 L308 V344 N346 D350 S351 M352	T299-I348 HydrophobicContact CG2-CD1 3.96Å; E304-I348 HydrophobicContact CB-CD1 4.35Å; E304-I348 HydrophobicContact CB-CG2 4.06Å; E304-I348 HydrophobicContact CG-CD1 4.09Å; E304-I348 WeakPolarHBondContact O-CG2 3.46Å; L307-I348 HydrophobicContact CB-CD1 4.02Å; L307-I348 HydrophobicContact CB-CG1 3.89Å; L307-I348 HydrophobicContact CD1-CD1 3.71Å; L307-I348 HydrophobicContact CD1-CG1 4.34Å; L308-I348 HydrophobicContact CB-CG2 4Å; V344-I348 HydrophobicContact CG1-CG1 4.03Å; V344-I348 VanDerWaalsContact O-CB 3.3Å; V344-I348 WeakPolarHBondContact O-CB 3.23Å; V344-I348 WeakPolarHBondContact O-CG1 3.22Å; V344-I348 PolarHBondContact O-N 2.89Å; N346-I348 PolarHBondContact O-N 3.2Å; I348-D350 VanDerWaalsContact C-N 3.33Å; I348-D350 PolarHBondContact O-N 3.24Å; I348-S351 PolarHBondContact O-N 3.05Å; I348-M352 HydrophobicContact CG2-CG 4.22Å; I348-M352 HydrophobicContact CG2-SD 3.81Å; I348-M352 WeakPolarHBondContact O-CB 3.42Å; I348-M352 VanDerWaalsContact O-CG 3.23Å; I348-M352 WeakPolarHBondContact O-CG 3.47Å; I348-M352 PolarHBondContact O-N 3.06Å
349	T	94.9	Very high	92.9	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-63.1	-40.5	177.1	51.4	0	0	0	0	111.7	K247 L308 F345 N346 L353	K247-T349 HydrophobicContact CB-CG2 4.32Å; K247-T349 HydrophobicContact CG-CG2 4.43Å; K247-T349 PolarHBondContact NZ-OG1 3.29Å; L308-T349 HydrophobicContact CD1-CG2 3.92Å; F345-T349 HydrophobicContact CD2-CG2 4.18Å; F345-T349 HydrophobicContact CE1-CG2 4.48Å; F345-T349 HydrophobicContact CE2-CG2 3.96Å; F345-T349 HydrophobicContact CZ-CG2 4.15Å; F345-T349 WeakPolarHBondContact O-CB 3.43Å; F345-T349 VanDerWaalsContact O-CG2 3.28Å; F345-T349 WeakPolarHBondContact O-CG2 3.37Å; F345-T349 PolarHBondContact O-N 3.17Å; F345-T349 PolarHBondContact O-OG1 3.49Å; N346-T349 PolarHBondContact O-OG1 3.19Å; N346-T349 VanDerWaalsContact O-OG1 3.07Å; T349-L353 WeakPolarHBondContact O-CB 3.35Å; T349-L353 WeakPolarHBondContact O-CD1 3.05Å; T349-L353 VanDerWaalsContact O-CG 3.23Å; T349-L353 WeakPolarHBondContact O-CG 3.24Å; T349-L353 PolarHBondContact O-N 2.96Å
350	D	93.6	Very high	92.4	Very high	40 Å²	40	35.7 Å²	35.7	21%	0.214	21%	0.208	C	C	.	.	H	α-helix	trans	-66.2	-45	175.8	-69.4	-16.4	0	0	0	111.9	K247 N346 I348 M352 L353 T354 L366 C369	K247-D350 WeakPolarHBondContact CE-OD1 3.21Å; K247-D350 IonicContact NZ-OD1 3.91Å; K247-D350 PolarHBondContact NZ-OD1 2.89Å; K247-D350 IonicContact NZ-OD2 2.66Å; N346-D350 WeakPolarHBondContact O-CB 3.48Å; N346-D350 VanDerWaalsContact O-CG 3.22Å; N346-D350 PolarHBondContact O-N 3.1Å; I348-D350 VanDerWaalsContact C-N 3.33Å; I348-D350 PolarHBondContact O-N 3.24Å; D350-M352 PolarHBondContact O-N 3.24Å; D350-L353 PolarHBondContact O-N 3.22Å; D350-T354 WeakPolarHBondContact O-CB 3.23Å; D350-T354 VanDerWaalsContact O-CG2 3.28Å; D350-T354 WeakPolarHBondContact O-CG2 3.21Å; D350-T354 PolarHBondContact O-N 3.5Å; D350-T354 PolarHBondContact O-OG1 3.36Å; D350-L366 HydrophobicContact CB-CD2 4.22Å; D350-C369 WeakPolarHBondContact OD1-CB 3.31Å; D350-C369 PolarHBondContact OD1-SG 3.13Å
351	S	93	Very high	92	Very high	32 Å²	32	34.9 Å²	34.9	22%	0.224	21%	0.205	C	C	.	.	H	α-helix	trans	-59.8	-46.8	175.9	-176.2	0	0	0	0	112.2	E304 V347 I348 L353 T354 K355	E304-S351 WeakPolarHBondContact OE1-CB 3.43Å; E304-S351 PolarHBondContact OE1-OG 3.25Å; V347-S351 VanDerWaalsContact O-CB 3.3Å; V347-S351 WeakPolarHBondContact O-CB 3.33Å; V347-S351 PolarHBondContact O-N 3.21Å; I348-S351 PolarHBondContact O-N 3.05Å; S351-L353 PolarHBondContact O-N 3.5Å; S351-T354 WeakPolarHBondContact CA-OG1 3.38Å; S351-T354 PolarHBondContact O-N 3.24Å; S351-T354 PolarHBondContact O-OG1 2.95Å; S351-K355 VanDerWaalsContact O-CG 3.31Å; S351-K355 WeakPolarHBondContact O-CG 3.49Å; S351-K355 PolarHBondContact O-N 3.3Å
352	M	94.5	Very high	91.3	Very high	24 Å²	24	36.9 Å²	36.9	12%	0.118	22%	0.217	C	C	.	.	H	α-helix	trans	-62.4	-44.4	178	-71.6	178.8	75.8	0	0	111.8	I243 E304 L308 I348 D350 K355 I356	I243-M352 HydrophobicContact CD1-CE 3.53Å; I243-M352 HydrophobicContact CD1-SD 4.45Å; I243-M352 HydrophobicContact CG1-CE 4.18Å; I243-M352 HydrophobicContact CG2-CB 4.18Å; E304-M352 HydrophobicContact CB-CG 4.09Å; E304-M352 HydrophobicContact CB-SD 4.3Å; E304-M352 VanDerWaalsContact OE2-CG 3.31Å; E304-M352 WeakPolarHBondContact OE2-CG 3.46Å; L308-M352 HydrophobicContact CD2-CE 4.48Å; L308-M352 HydrophobicContact CD2-SD 4.04Å; I348-M352 HydrophobicContact CG2-CG 4.22Å; I348-M352 HydrophobicContact CG2-SD 3.81Å; I348-M352 WeakPolarHBondContact O-CB 3.42Å; I348-M352 VanDerWaalsContact O-CG 3.23Å; I348-M352 WeakPolarHBondContact O-CG 3.47Å; I348-M352 PolarHBondContact O-N 3.06Å; D350-M352 PolarHBondContact O-N 3.24Å; M352-K355 PolarHBondContact O-N 3.05Å; M352-I356 WeakPolarHBondContact O-CD1 3.34Å; M352-I356 VanDerWaalsContact O-CG1 3.25Å; M352-I356 WeakPolarHBondContact O-CG1 3.4Å; M352-I356 PolarHBondContact O-N 3.32Å
353	L	93.8	Very high	90.5	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-65.6	-41.9	-179.8	-75.7	163.1	0	0	0	112	V240 I243 F244 K247 T349 D350 S351 K355 I356 M365 C369	V240-L353 HydrophobicContact CB-CD2 4.45Å; V240-L353 HydrophobicContact CG1-CD2 3.97Å; I243-L353 HydrophobicContact CB-CD2 3.86Å; I243-L353 HydrophobicContact CB-CG 4.14Å; I243-L353 HydrophobicContact CG2-CD1 4.14Å; I243-L353 HydrophobicContact CG2-CD2 4.02Å; I243-L353 HydrophobicContact CG2-CG 3.71Å; F244-L353 HydrophobicContact CB-CD2 4.25Å; F244-L353 HydrophobicContact CD2-CD1 4.2Å; K247-L353 HydrophobicContact CD-CD1 4.28Å; T349-L353 WeakPolarHBondContact O-CB 3.35Å; T349-L353 WeakPolarHBondContact O-CD1 3.05Å; T349-L353 VanDerWaalsContact O-CG 3.23Å; T349-L353 WeakPolarHBondContact O-CG 3.24Å; T349-L353 PolarHBondContact O-N 2.96Å; D350-L353 PolarHBondContact O-N 3.22Å; S351-L353 PolarHBondContact O-N 3.5Å; L353-K355 VanDerWaalsContact C-N 3.33Å; L353-K355 PolarHBondContact O-N 2.96Å; L353-I356 PolarHBondContact O-N 3.45Å; L353-M365 HydrophobicContact CB-CE 3.82Å; L353-M365 HydrophobicContact CB-CG 4.01Å; L353-M365 HydrophobicContact CB-SD 4.24Å; L353-M365 HydrophobicContact CD1-CE 3.79Å; L353-M365 HydrophobicContact CD2-CE 3.78Å; L353-M365 HydrophobicContact CD2-SD 4.39Å; L353-M365 HydrophobicContact CG-CE 3.99Å; L353-C369 VanDerWaalsContact CD1-SG 3.52Å
354	T	91.9	Very high	90	Very high	29 Å²	29	41.2 Å²	41.2	18%	0.178	26%	0.255	C	S	.	.	H	α-helix	trans	-68.6	-27.7	178.1	51.2	0	0	0	0	113.8	D350 S351 T362 L366	D350-T354 WeakPolarHBondContact O-CB 3.23Å; D350-T354 VanDerWaalsContact O-CG2 3.28Å; D350-T354 WeakPolarHBondContact O-CG2 3.21Å; D350-T354 PolarHBondContact O-N 3.5Å; D350-T354 PolarHBondContact O-OG1 3.36Å; S351-T354 WeakPolarHBondContact CA-OG1 3.38Å; S351-T354 PolarHBondContact O-N 3.24Å; S351-T354 PolarHBondContact O-OG1 2.95Å; T354-T362 HydrophobicContact CG2-CG2 3.74Å; T354-L366 HydrophobicContact CG2-CD1 4.28Å; T354-L366 HydrophobicContact CG2-CD2 3.58Å; T354-L366 HydrophobicContact CG2-CG 3.64Å
355	K	92.6	Very high	89.7	Confident	139 Å²	139	41.1 Å²	41.1	60%	0.604	25%	0.254	S	S	*	.	H	α-helix	trans	-76.8	-22.6	174.2	-73	175.3	-176.8	174.4	0	114.2	E304 S351 M352 L353	E304-K355 VanDerWaalsContact CD-NZ 3.33Å; E304-K355 WeakPolarHBondContact OE1-CE 3.38Å; E304-K355 IonicContact OE1-NZ 3.58Å; E304-K355 PolarHBondContact OE1-NZ 2.92Å; E304-K355 IonicContact OE2-NZ 2.74Å; S351-K355 VanDerWaalsContact O-CG 3.31Å; S351-K355 WeakPolarHBondContact O-CG 3.49Å; S351-K355 PolarHBondContact O-N 3.3Å; M352-K355 PolarHBondContact O-N 3.05Å; L353-K355 VanDerWaalsContact C-N 3.33Å; L353-K355 PolarHBondContact O-N 2.96Å
356	I	93.5	Very high	89.1	Confident	58 Å²	58	44.6 Å²	44.6	30%	0.297	27%	0.273	S	S	.	.	H	α-helix	trans	-79	-33.9	180	-65.3	161.7	0	0	0	111.1	F237 P238 V240 I243 M352 L353	F237-I356 HydrophobicContact CB-CG2 4.41Å; P238-I356 WeakPolarHBondContact O-CG2 3.29Å; V240-I356 HydrophobicContact CG2-CB 4.04Å; V240-I356 HydrophobicContact CG2-CG2 3.49Å; V240-I356 VanDerWaalsContact CG2-CG2 3.49Å; I243-I356 HydrophobicContact CG1-CD1 4.19Å; M352-I356 WeakPolarHBondContact O-CD1 3.34Å; M352-I356 VanDerWaalsContact O-CG1 3.25Å; M352-I356 WeakPolarHBondContact O-CG1 3.4Å; M352-I356 PolarHBondContact O-N 3.32Å; L353-I356 PolarHBondContact O-N 3.45Å
357	V	91.8	Very high	88.6	Confident	10 Å²	10	44.6 Å²	44.6	6%	0.061	28%	0.28	C	S	.	.	S	Bend	trans	-88.4	155.7	-177.5	-59.7	0	0	0	0	111.7	L234 V240 D361 M365	L234-V357 HydrophobicContact CD2-CG1 4.13Å; V240-V357 HydrophobicContact CG2-CG1 3.92Å; V357-D361 HydrophobicContact CB-CB 4.23Å; V357-D361 HydrophobicContact CG2-CB 4.39Å; V357-M365 HydrophobicContact CG1-CG 4.3Å; V357-M365 HydrophobicContact CG1-SD 4.18Å; V357-M365 HydrophobicContact CG2-CB 3.95Å; V357-M365 HydrophobicContact CG2-CG 4.17Å
358	P	90.3	Very high	88.4	Confident	54 Å²	54	42.9 Å²	42.9	35%	0.351	27%	0.268	S	S	.	.			trans	-59.4	151.9	172.6	-22.5	33.7	0	0	0	112	F237 S360 D361 T362	F237-P358 HydrophobicContact CE1-CG 3.88Å; F237-P358 HydrophobicContact CZ-CG 3.85Å; P358-S360 PolarHBondContact O-N 3.41Å; P358-D361 WeakPolarHBondContact O-CB 3.32Å; P358-D361 PolarHBondContact O-N 3.2Å; P358-T362 PolarHBondContact O-N 3.49Å
359	S	84.9	Confident	88.1	Confident	115 Å²	115	42.9 Å²	42.9	80%	0.804	27%	0.269	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.7	-22.8	-179.4	-48.5	0	0	0	0	114.1	D361	S359-D361 PolarHBondContact O-N 3.37Å
360	S	81.7	Confident	87.6	Confident	99 Å²	99	45.5 Å²	45.5	69%	0.692	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.7	-24.4	172.8	60.9	0	0	0	0	113.3	P358	P358-S360 PolarHBondContact O-N 3.41Å
361	D	85.8	Confident	87.3	Confident	13 Å²	13	45.3 Å²	45.3	7%	0.07	29%	0.292	C	S	.	.	T	Hydrogen-bonded Turn	trans	-106.8	-7.4	-169.2	-74.3	4.6	0	0	0	112.8	R233 L234 V357 P358 S359 G363 T364 M365	R233-D361 IonicContact CZ-OD2 3.59Å; R233-D361 IonicContact NE-OD2 3.8Å; R233-D361 IonicContact NH2-OD1 2.9Å; R233-D361 PolarHBondContact NH2-OD1 2.98Å; R233-D361 IonicContact NH2-OD2 2.72Å; R233-D361 PolarHBondContact NH2-OD2 3.3Å; L234-D361 HydrophobicContact CD2-CB 3.74Å; L234-D361 WeakPolarHBondContact CD2-OD2 3.39Å; V357-D361 HydrophobicContact CB-CB 4.23Å; V357-D361 HydrophobicContact CG2-CB 4.39Å; P358-D361 WeakPolarHBondContact O-CB 3.32Å; P358-D361 PolarHBondContact O-N 3.2Å; S359-D361 PolarHBondContact O-N 3.37Å; D361-G363 VanDerWaalsContact C-N 3.28Å; D361-G363 PolarHBondContact O-N 3.02Å; D361-T364 PolarHBondContact O-N 3.49Å; D361-T364 VanDerWaalsContact O-N 3.1Å; D361-M365 PolarHBondContact O-N 3.19Å
362	T	81.2	Confident	87.1	Confident	42 Å²	42	44.6 Å²	44.6	26%	0.258	29%	0.286	S	S	.	.	H	α-helix	trans	-52.3	-43	-179	-59.2	0	0	0	0	112.8	T354 P358 M365 L366	T354-T362 HydrophobicContact CG2-CG2 3.74Å; P358-T362 PolarHBondContact O-N 3.49Å; T362-M365 PolarHBondContact O-N 3.38Å; T362-L366 HydrophobicContact CG2-CD1 4.2Å; T362-L366 WeakPolarHBondContact O-CG 3.24Å; T362-L366 PolarHBondContact O-N 3.04Å
363	G	75.3	Confident	86.8	Confident	55 Å²	55	48.3 Å²	48.3	57%	0.567	30%	0.304	S	S	*	.	H	α-helix	trans	-64.3	-44.1	178.9	0	0	0	0	0	112.6	D361 M365 L366 G367	D361-G363 VanDerWaalsContact C-N 3.28Å; D361-G363 PolarHBondContact O-N 3.02Å; G363-M365 VanDerWaalsContact C-N 3.34Å; G363-M365 PolarHBondContact O-N 3.47Å; G363-L366 PolarHBondContact O-N 2.96Å; G363-G367 PolarHBondContact O-N 2.88Å
364	T	82.4	Confident	86.5	Confident	59 Å²	59	50 Å²	50	36%	0.362	32%	0.315	S	S	.	.	H	α-helix	trans	-65.3	-39	177	-49.8	0	0	0	0	111.2	L234 D361 G367 L368	L234-T364 HydrophobicContact CD1-CG2 3.52Å; D361-T364 PolarHBondContact O-N 3.49Å; D361-T364 VanDerWaalsContact O-N 3.1Å; T364-G367 PolarHBondContact O-N 3.47Å; T364-L368 PolarHBondContact O-N 2.93Å
365	M	87.6	Confident	86.4	Confident	0 Å²	0	53 Å²	53	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-64.1	-44.8	175.3	-173.7	66	-122.3	0	0	112.1	V240 F244 L353 V357 D361 T362 G363 G367 L368 C369	V240-M365 HydrophobicContact CG1-CE 4.48Å; V240-M365 HydrophobicContact CG1-SD 4.1Å; F244-M365 HydrophobicContact CD2-CE 3.98Å; F244-M365 HydrophobicContact CE2-CE 4.34Å; L353-M365 HydrophobicContact CB-CE 3.82Å; L353-M365 HydrophobicContact CB-CG 4.01Å; L353-M365 HydrophobicContact CB-SD 4.24Å; L353-M365 HydrophobicContact CD1-CE 3.79Å; L353-M365 HydrophobicContact CD2-CE 3.78Å; L353-M365 HydrophobicContact CD2-SD 4.39Å; L353-M365 HydrophobicContact CG-CE 3.99Å; V357-M365 HydrophobicContact CG1-CG 4.3Å; V357-M365 HydrophobicContact CG1-SD 4.18Å; V357-M365 HydrophobicContact CG2-CB 3.95Å; V357-M365 HydrophobicContact CG2-CG 4.17Å; D361-M365 PolarHBondContact O-N 3.19Å; T362-M365 PolarHBondContact O-N 3.38Å; G363-M365 VanDerWaalsContact C-N 3.34Å; G363-M365 PolarHBondContact O-N 3.47Å; M365-G367 VanDerWaalsContact C-N 3.29Å; M365-G367 PolarHBondContact O-N 3.39Å; M365-L368 HydrophobicContact CE-CB 4.33Å; M365-L368 HydrophobicContact CE-CD2 3.99Å; M365-L368 HydrophobicContact CE-CG 4.49Å; M365-L368 WeakPolarHBondContact O-CB 3.44Å; M365-L368 PolarHBondContact O-N 3.49Å; M365-L368 VanDerWaalsContact O-N 3.15Å; M365-C369 PolarHBondContact O-N 2.7Å
366	L	83.4	Confident	86.3	Confident	78 Å²	78	47.1 Å²	47.1	41%	0.408	31%	0.306	S	S	.	.	H	α-helix	trans	-62.9	-36.7	174.1	-72.8	172.7	0	0	0	111.9	D350 T354 T362 G363 L368 C369 A370	D350-L366 HydrophobicContact CB-CD2 4.22Å; T354-L366 HydrophobicContact CG2-CD1 4.28Å; T354-L366 HydrophobicContact CG2-CD2 3.58Å; T354-L366 HydrophobicContact CG2-CG 3.64Å; T362-L366 HydrophobicContact CG2-CD1 4.2Å; T362-L366 WeakPolarHBondContact O-CG 3.24Å; T362-L366 PolarHBondContact O-N 3.04Å; G363-L366 PolarHBondContact O-N 2.96Å; L366-L368 VanDerWaalsContact C-N 3.34Å; L366-L368 PolarHBondContact O-N 3.47Å; L366-C369 WeakPolarHBondContact O-CB 3.5Å; L366-C369 PolarHBondContact O-N 2.93Å; L366-A370 PolarHBondContact O-N 3.39Å
367	G	81.6	Confident	86	Confident	30 Å²	30	49.5 Å²	49.5	31%	0.309	31%	0.311	S	S	.	.	H	α-helix	trans	-60.1	-41.8	171.5	0	0	0	0	0	112.7	G363 T364 M365 A370 S371	G363-G367 PolarHBondContact O-N 2.88Å; T364-G367 PolarHBondContact O-N 3.47Å; M365-G367 VanDerWaalsContact C-N 3.29Å; M365-G367 PolarHBondContact O-N 3.39Å; G367-A370 PolarHBondContact O-N 2.76Å; G367-S371 PolarHBondContact O-N 3.15Å; G367-S371 PolarHBondContact O-OG 3.19Å
368	L	87.8	Confident	86	Confident	21 Å²	21	49.3 Å²	49.3	11%	0.11	31%	0.309	C	S	.	.	H	α-helix	trans	-64.8	-41.3	174.4	-173.5	64.6	0	0	0	111.7	I231 M235 F244 T364 M365 L366 S371 V372	I231-L368 HydrophobicContact CG2-CD1 3.95Å; I231-L368 HydrophobicContact CG2-CD2 4.47Å; M235-L368 HydrophobicContact SD-CD2 3.94Å; F244-L368 HydrophobicContact CD2-CD2 4.26Å; F244-L368 HydrophobicContact CD2-CG 4.48Å; F244-L368 HydrophobicContact CE1-CD2 4.45Å; F244-L368 HydrophobicContact CE2-CD1 4.43Å; F244-L368 HydrophobicContact CE2-CD2 3.76Å; F244-L368 HydrophobicContact CE2-CG 3.55Å; F244-L368 HydrophobicContact CZ-CD1 3.96Å; F244-L368 HydrophobicContact CZ-CD2 3.86Å; F244-L368 HydrophobicContact CZ-CG 3.58Å; T364-L368 PolarHBondContact O-N 2.93Å; M365-L368 HydrophobicContact CE-CB 4.33Å; M365-L368 HydrophobicContact CE-CD2 3.99Å; M365-L368 HydrophobicContact CE-CG 4.49Å; M365-L368 WeakPolarHBondContact O-CB 3.44Å; M365-L368 PolarHBondContact O-N 3.49Å; M365-L368 VanDerWaalsContact O-N 3.15Å; L366-L368 VanDerWaalsContact C-N 3.34Å; L366-L368 PolarHBondContact O-N 3.47Å; L368-S371 WeakPolarHBondContact O-CB 3.44Å; L368-S371 PolarHBondContact O-N 3.46Å; L368-V372 PolarHBondContact O-N 2.89Å
369	C	88	Confident	86.1	Confident	3 Å²	3	49.6 Å²	49.6	2%	0.02	31%	0.307	C	S	.	.	H	α-helix	trans	-60.5	-44.9	173.2	-71.9	0	0	0	0	112.6	D350 L353 M365 L366 S371 V372	D350-C369 WeakPolarHBondContact OD1-CB 3.31Å; D350-C369 PolarHBondContact OD1-SG 3.13Å; L353-C369 VanDerWaalsContact CD1-SG 3.52Å; M365-C369 PolarHBondContact O-N 2.7Å; L366-C369 WeakPolarHBondContact O-CB 3.5Å; L366-C369 PolarHBondContact O-N 2.93Å; C369-S371 VanDerWaalsContact C-N 3.25Å; C369-S371 PolarHBondContact O-N 3.44Å; C369-V372 WeakPolarHBondContact O-CB 3.38Å; C369-V372 PolarHBondContact O-N 3.31Å
370	A	84.9	Confident	86.5	Confident	54 Å²	54	44.1 Å²	44.1	45%	0.446	27%	0.269	S	S	.	.	H	α-helix	trans	-65.1	-30	176.6	0	0	0	0	0	112.6	L366 G367 V372 Q373 S374	L366-A370 PolarHBondContact O-N 3.39Å; G367-A370 PolarHBondContact O-N 2.76Å; A370-V372 VanDerWaalsContact C-N 3.3Å; A370-V372 PolarHBondContact O-N 2.98Å; A370-Q373 PolarHBondContact O-N 2.95Å; A370-S374 PolarHBondContact O-N 2.87Å; A370-S374 VanDerWaalsContact O-N 3.11Å; A370-S374 PolarHBondContact O-OG 3.39Å
371	S	87.6	Confident	87.1	Confident	36 Å²	36	39.5 Å²	39.5	25%	0.252	24%	0.237	S	C	.	.	H	α-helix	trans	-65.1	-33.2	175.3	-58.3	0	0	0	0	111.9	G367 L368 C369 S374 L375	G367-S371 PolarHBondContact O-N 3.15Å; G367-S371 PolarHBondContact O-OG 3.19Å; L368-S371 WeakPolarHBondContact O-CB 3.44Å; L368-S371 PolarHBondContact O-N 3.46Å; C369-S371 VanDerWaalsContact C-N 3.25Å; C369-S371 PolarHBondContact O-N 3.44Å; S371-S374 PolarHBondContact O-N 3.21Å; S371-L375 WeakPolarHBondContact O-CB 3.4Å; S371-L375 PolarHBondContact O-N 2.68Å
372	V	89.3	Confident	87.5	Confident	17 Å²	17	40.5 Å²	40.5	10%	0.103	24%	0.244	C	C	.	.	H	α-helix	trans	-60.9	-46.1	174	177.1	0	0	0	0	111	F244 I248 L368 C369 A370 S374 L375 V376	F244-V372 HydrophobicContact CE1-CG2 4.42Å; F244-V372 HydrophobicContact CE2-CG2 3.67Å; F244-V372 HydrophobicContact CZ-CG2 3.49Å; F244-V372 VanDerWaalsContact CZ-CG2 3.49Å; I248-V372 HydrophobicContact CD1-CG2 4.33Å; I248-V372 HydrophobicContact CG1-CG1 3.93Å; I248-V372 HydrophobicContact CG1-CG2 3.97Å; L368-V372 PolarHBondContact O-N 2.89Å; C369-V372 WeakPolarHBondContact O-CB 3.38Å; C369-V372 PolarHBondContact O-N 3.31Å; A370-V372 VanDerWaalsContact C-N 3.3Å; A370-V372 PolarHBondContact O-N 2.98Å; V372-S374 VanDerWaalsContact C-N 3.31Å; V372-S374 PolarHBondContact O-N 3.47Å; V372-L375 WeakPolarHBondContact O-CB 3.31Å; V372-L375 PolarHBondContact O-N 2.93Å; V372-V376 WeakPolarHBondContact O-CG2 3.38Å; V372-V376 PolarHBondContact O-N 3.19Å
373	Q	86.8	Confident	88.2	Confident	103 Å²	103	41.6 Å²	41.6	48%	0.481	25%	0.247	S	C	.	.	H	α-helix	trans	-64.5	-38.1	177	-69.1	-164.8	1.6	0	0	112.2	N346 A370 L375 V376 R377	N346-Q373 PolarHBondContact OD1-NE2 2.88Å; A370-Q373 PolarHBondContact O-N 2.95Å; Q373-L375 VanDerWaalsContact C-N 3.34Å; Q373-V376 PolarHBondContact O-N 2.83Å; Q373-R377 WeakPolarHBondContact O-CB 3.24Å; Q373-R377 PolarHBondContact O-N 3.47Å
374	S	87.6	Confident	89.1	Confident	35 Å²	35	39 Å²	39	25%	0.245	22%	0.22	C	C	.	.	H	α-helix	trans	-64.9	-40.1	176.3	-58.8	0	0	0	0	111.6	A370 S371 V372 R377 T378	A370-S374 PolarHBondContact O-N 2.87Å; A370-S374 VanDerWaalsContact O-N 3.11Å; A370-S374 PolarHBondContact O-OG 3.39Å; S371-S374 PolarHBondContact O-N 3.21Å; V372-S374 VanDerWaalsContact C-N 3.31Å; V372-S374 PolarHBondContact O-N 3.47Å; S374-R377 PolarHBondContact O-N 3.16Å; S374-T378 WeakPolarHBondContact O-CB 3.31Å; S374-T378 PolarHBondContact O-N 3.27Å; S374-T378 PolarHBondContact O-OG1 3.4Å
375	L	89.6	Confident	89.6	Confident	91 Å²	91	36.1 Å²	36.1	48%	0.476	20%	0.203	S	C	.	.	H	α-helix	trans	-61.6	-51.8	174	-179.9	64	0	0	0	110.6	S371 V372 Q373 R377 T378 I379	S371-L375 WeakPolarHBondContact O-CB 3.4Å; S371-L375 PolarHBondContact O-N 2.68Å; V372-L375 WeakPolarHBondContact O-CB 3.31Å; V372-L375 PolarHBondContact O-N 2.93Å; Q373-L375 VanDerWaalsContact C-N 3.34Å; L375-R377 VanDerWaalsContact C-N 3.3Å; L375-R377 PolarHBondContact O-N 3.22Å; L375-T378 CarbonylContact O-C 3.58Å; L375-T378 WeakPolarHBondContact O-CA 3.21Å; L375-T378 WeakPolarHBondContact O-CB 3.21Å; L375-T378 PolarHBondContact O-N 3.25Å; L375-I379 HydrophobicContact CD1-CD1 4.09Å; L375-I379 HydrophobicContact CD1-CG1 4.47Å; L375-I379 HydrophobicContact CD1-CG2 4.07Å; L375-I379 HydrophobicContact CG-CD1 4.01Å; L375-I379 HydrophobicContact CG-CG1 4.44Å; L375-I379 WeakPolarHBondContact O-CG1 3.48Å; L375-I379 PolarHBondContact O-N 2.89Å
376	V	91.1	Very high	90	Very high	17 Å²	17	40.9 Å²	40.9	10%	0.103	22%	0.224	C	C	.	.	H	α-helix	trans	-57.6	-42.2	177.4	172.3	0	0	0	0	111.3	L252 V372 Q373 T378 G380	L252-V376 HydrophobicContact CD1-CG2 4.23Å; V372-V376 WeakPolarHBondContact O-CG2 3.38Å; V372-V376 PolarHBondContact O-N 3.19Å; Q373-V376 PolarHBondContact O-N 2.83Å; V376-T378 PolarHBondContact O-N 3.14Å; V376-G380 WeakPolarHBondContact O-CA 3.23Å; V376-G380 PolarHBondContact O-N 2.97Å
377	R	87.8	Confident	90.5	Very high	108 Å²	108	38.3 Å²	38.3	41%	0.408	21%	0.21	S	C	.	.	H	α-helix	trans	-64.2	-29.6	175.4	-169.1	172	73.4	-130.6	6.2	113	Q373 S374 L375 P381	Q373-R377 WeakPolarHBondContact O-CB 3.24Å; Q373-R377 PolarHBondContact O-N 3.47Å; S374-R377 PolarHBondContact O-N 3.16Å; L375-R377 VanDerWaalsContact C-N 3.3Å; L375-R377 PolarHBondContact O-N 3.22Å; R377-P381 WeakPolarHBondContact O-CD 3.26Å; R377-P381 WeakPolarHBondContact O-CG 3.49Å
378	T	91.8	Very high	91.1	Very high	5 Å²	5	38.5 Å²	38.5	3%	0.031	20%	0.202	C	C	.	.	H	α-helix	trans	-80.2	-55.8	179.7	-55.7	0	0	0	0	111.3	T72 G75 L76 S374 L375 V376	T72-T378 WeakPolarHBondContact CA-O 3.31Å; T72-T378 WeakPolarHBondContact CB-O 3.4Å; T72-T378 HydrophobicContact CG2-CG2 4.28Å; T72-T378 VanDerWaalsContact CG2-O 3.25Å; T72-T378 WeakPolarHBondContact CG2-O 3.45Å; T72-T378 PolarHBondContact OG1-O 2.97Å; G75-T378 VanDerWaalsContact CA-OG1 3.26Å; G75-T378 WeakPolarHBondContact CA-OG1 3.44Å; L76-T378 HydrophobicContact CD2-CG2 3.77Å; L76-T378 HydrophobicContact CG-CG2 3.79Å; S374-T378 WeakPolarHBondContact O-CB 3.31Å; S374-T378 PolarHBondContact O-N 3.27Å; S374-T378 PolarHBondContact O-OG1 3.4Å; L375-T378 CarbonylContact O-C 3.58Å; L375-T378 WeakPolarHBondContact O-CA 3.21Å; L375-T378 WeakPolarHBondContact O-CB 3.21Å; L375-T378 PolarHBondContact O-N 3.25Å; V376-T378 PolarHBondContact O-N 3.14Å
379	I	92.3	Very high	91.4	Very high	60 Å²	60	41.8 Å²	41.8	31%	0.308	22%	0.218	S	C	.	.	H	α-helix	trans	-89.6	-25.9	-173.8	68.7	179.4	0	0	0	113	L375 T382 I383	L375-I379 HydrophobicContact CD1-CD1 4.09Å; L375-I379 HydrophobicContact CD1-CG1 4.47Å; L375-I379 HydrophobicContact CD1-CG2 4.07Å; L375-I379 HydrophobicContact CG-CD1 4.01Å; L375-I379 HydrophobicContact CG-CG1 4.44Å; L375-I379 WeakPolarHBondContact O-CG1 3.48Å; L375-I379 PolarHBondContact O-N 2.89Å; I379-T382 PolarHBondContact O-N 3.32Å; I379-I383 HydrophobicContact CB-CD1 4.2Å; I379-I383 HydrophobicContact CD1-CD1 4.02Å; I379-I383 HydrophobicContact CG1-CD1 3.95Å; I379-I383 WeakPolarHBondContact O-CG1 3.47Å; I379-I383 PolarHBondContact O-N 3.34Å
380	G	93.8	Very high	91.7	Very high	1 Å²	1	46.2 Å²	46.2	1%	0.01	24%	0.241	C	C	.	.	H	α-helix	trans	-58.9	-39.1	-175.3	0	0	0	0	0	114.1	V376 T382 I383 G384	V376-G380 WeakPolarHBondContact O-CA 3.23Å; V376-G380 PolarHBondContact O-N 2.97Å; G380-T382 PolarHBondContact O-N 2.74Å; G380-I383 PolarHBondContact O-N 3.08Å; G380-G384 WeakPolarHBondContact O-CA 3.17Å; G380-G384 PolarHBondContact O-N 3.36Å
381	P	93.6	Very high	92.1	Very high	2 Å²	2	51 Å²	51	1%	0.013	25%	0.249	C	C	.	.	H	α-helix	trans	-64	-39.1	176.3	-25.5	35.6	0	0	0	114.3	Q71 V259 M260 R377 G385	Q71-P381 HydrophobicContact CB-CB 3.62Å; Q71-P381 HydrophobicContact CB-CG 3.63Å; Q71-P381 HydrophobicContact CG-CB 4.49Å; V259-P381 HydrophobicContact CB-CG 4.15Å; V259-P381 HydrophobicContact CG2-CG 3.91Å; M260-P381 HydrophobicContact CE-CB 3.58Å; M260-P381 HydrophobicContact CE-CG 4.4Å; R377-P381 WeakPolarHBondContact O-CD 3.26Å; R377-P381 WeakPolarHBondContact O-CG 3.49Å; P381-G385 PolarHBondContact O-N 3Å
382	T	94.2	Very high	92.4	Very high	34 Å²	34	50.7 Å²	50.7	21%	0.209	25%	0.252	C	S	.	.	H	α-helix	trans	-70	-46.3	176.8	-66.4	0	0	0	0	111	Y69 T72 I379 G380 G385 F386	Y69-T382 HydrophobicContact CD1-CG2 3.95Å; Y69-T382 HydrophobicContact CE1-CG2 3.6Å; T72-T382 WeakPolarHBondContact CB-OG1 3.08Å; T72-T382 PolarHBondContact OG1-OG1 3.19Å; I379-T382 PolarHBondContact O-N 3.32Å; G380-T382 PolarHBondContact O-N 2.74Å; T382-G385 PolarHBondContact O-N 2.95Å; T382-F386 WeakPolarHBondContact O-CB 3.34Å; T382-F386 PolarHBondContact O-N 2.77Å
383	I	94.9	Very high	92.5	Very high	64 Å²	64	50.3 Å²	50.3	33%	0.328	25%	0.249	S	C	.	.	H	α-helix	trans	-62.3	-48.1	177.5	-64.3	170.7	0	0	0	110.4	I256 I379 G380 F386 L387	I256-I383 HydrophobicContact CD1-CB 4.41Å; I256-I383 HydrophobicContact CD1-CG2 3.82Å; I379-I383 HydrophobicContact CB-CD1 4.2Å; I379-I383 HydrophobicContact CD1-CD1 4.02Å; I379-I383 HydrophobicContact CG1-CD1 3.95Å; I379-I383 WeakPolarHBondContact O-CG1 3.47Å; I379-I383 PolarHBondContact O-N 3.34Å; G380-I383 PolarHBondContact O-N 3.08Å; I383-F386 PolarHBondContact O-N 3.44Å; I383-L387 HydrophobicContact CG2-CD1 3.94Å; I383-L387 HydrophobicContact CG2-CG 4.41Å; I383-L387 WeakPolarHBondContact O-CB 3.48Å; I383-L387 VanDerWaalsContact O-CG 3.28Å; I383-L387 WeakPolarHBondContact O-CG 3.45Å; I383-L387 PolarHBondContact O-N 3.32Å
384	G	94.6	Very high	92.9	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-63.4	-41.1	178.8	0	0	0	0	0	112.7	I256 M260 G380 L387 Y388	I256-G384 VanDerWaalsContact CG2-CA 3.47Å; M260-G384 VanDerWaalsContact SD-C 3.54Å; G380-G384 WeakPolarHBondContact O-CA 3.17Å; G380-G384 PolarHBondContact O-N 3.36Å; G384-L387 PolarHBondContact O-N 3.49Å; G384-Y388 WeakPolarHBondContact O-CB 3.43Å; G384-Y388 PolarHBondContact O-N 2.95Å
385	G	93.4	Very high	93.3	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-63.8	-43.6	175.9	0	0	0	0	0	112	M260 P381 T382 Y388 M389	M260-G385 PolarHBondContact SD-N 3.31Å; P381-G385 PolarHBondContact O-N 3Å; T382-G385 PolarHBondContact O-N 2.95Å; G385-Y388 PolarHBondContact O-N 3.33Å; G385-M389 WeakPolarHBondContact O-CB 3.18Å; G385-M389 WeakPolarHBondContact O-CG 3.42Å; G385-M389 PolarHBondContact O-N 3.23Å
386	F	94.9	Very high	93.5	Very high	99 Å²	99	42.2 Å²	42.2	43%	0.434	21%	0.213	S	C	.	.	H	α-helix	trans	-61.5	-47.4	174.1	177.2	-94	0	0	0	112.1	L65 T382 I383 M389 N390 Y391	L65-F386 HydrophobicContact CD1-CB 4.28Å; T382-F386 WeakPolarHBondContact O-CB 3.34Å; T382-F386 PolarHBondContact O-N 2.77Å; I383-F386 PolarHBondContact O-N 3.44Å; F386-M389 PolarHBondContact O-N 3.03Å; F386-N390 VanDerWaalsContact CD2-ND2 3.27Å; F386-N390 WeakPolarHBondContact CD2-ND2 3.47Å; F386-N390 VanDerWaalsContact CE2-ND2 3.32Å; F386-N390 WeakPolarHBondContact CE2-ND2 3.33Å; F386-N390 WeakPolarHBondContact O-CB 3.31Å; F386-N390 PolarHBondContact O-N 3.25Å; F386-N390 VanDerWaalsContact O-N 3.07Å; F386-N390 PolarHBondContact O-ND2 2.93Å; F386-Y391 HydrophobicContact CE1-CE2 4.06Å
387	L	95.3	Very high	93.7	Very high	25 Å²	25	41.5 Å²	41.5	13%	0.131	21%	0.209	C	C	.	.	H	α-helix	trans	-60.7	-45.9	177.3	-72.9	173	0	0	0	111.3	I383 G384 Y391 G392 S395 I396 I399	I383-L387 HydrophobicContact CG2-CD1 3.94Å; I383-L387 HydrophobicContact CG2-CG 4.41Å; I383-L387 WeakPolarHBondContact O-CB 3.48Å; I383-L387 VanDerWaalsContact O-CG 3.28Å; I383-L387 WeakPolarHBondContact O-CG 3.45Å; I383-L387 PolarHBondContact O-N 3.32Å; G384-L387 PolarHBondContact O-N 3.49Å; L387-Y391 HydrophobicContact CD2-CD2 4.24Å; L387-Y391 CarbonylContact O-C 3.2Å; L387-Y391 WeakPolarHBondContact O-CA 3.49Å; L387-Y391 WeakPolarHBondContact O-CB 3.16Å; L387-Y391 PolarHBondContact O-N 3.25Å; L387-G392 PolarHBondContact O-N 2.84Å; L387-S395 PolarHBondContact O-OG 2.9Å; L387-I396 HydrophobicContact CB-CG1 4.21Å; L387-I399 HydrophobicContact CD1-CD1 3.7Å; L387-I399 HydrophobicContact CD2-CD1 3.72Å; L387-I399 HydrophobicContact CG-CD1 4.36Å
388	Y	94.4	Very high	94.2	Very high	33 Å²	33	39.1 Å²	39.1	13%	0.129	20%	0.204	C	C	.	.	H	α-helix	trans	-63.5	-44.8	-179.6	-173.8	-90.9	0	0	0	112.3	T64 I264 D267 F268 G384 G385 G392 L393	T64-Y388 HydrophobicContact CG2-CD1 3.65Å; T64-Y388 HydrophobicContact CG2-CE1 4.43Å; T64-Y388 HydrophobicContact CG2-CG 4.22Å; I264-Y388 HydrophobicContact CG1-CD2 4.24Å; I264-Y388 HydrophobicContact CG1-CE2 4.09Å; D267-Y388 HydrophobicContact CB-CE1 4.1Å; D267-Y388 WeakPolarHBondContact CB-OH 3.19Å; F268-Y388 HydrophobicContact CB-CE2 4.45Å; F268-Y388 WeakPolarHBondContact CB-OH 3.44Å; F268-Y388 PolarHBondContact N-OH 3.42Å; F268-Y388 VanDerWaalsContact N-OH 3.15Å; G384-Y388 WeakPolarHBondContact O-CB 3.43Å; G384-Y388 PolarHBondContact O-N 2.95Å; G385-Y388 PolarHBondContact O-N 3.33Å; Y388-G392 WeakPolarHBondContact O-CA 3.36Å; Y388-G392 PolarHBondContact O-N 2.94Å; Y388-L393 HydrophobicContact CD2-CB 4.34Å; Y388-L393 HydrophobicContact CE2-CB 4.04Å; Y388-L393 HydrophobicContact CE2-CD1 4.47Å
389	M	92.8	Very high	94.4	Very high	91 Å²	91	42 Å²	42	45%	0.448	22%	0.219	S	C	.	.	H	α-helix	trans	-71.4	-38.4	-178.9	-74.5	-172.5	66.6	0	0	113.6	D63 T64 L65 G385 F386	D63-M389 HydrophobicContact CB-CE 4.37Å; D63-M389 HydrophobicContact CB-SD 4.48Å; T64-M389 HydrophobicContact CG2-CG 4.13Å; L65-M389 HydrophobicContact CB-SD 3.42Å; L65-M389 WeakPolarHBondContact CB-SD 3.41Å; L65-M389 PolarHBondContact N-SD 3.47Å; L65-M389 VanDerWaalsContact N-SD 3.39Å; G385-M389 WeakPolarHBondContact O-CB 3.18Å; G385-M389 WeakPolarHBondContact O-CG 3.42Å; G385-M389 PolarHBondContact O-N 3.23Å; F386-M389 PolarHBondContact O-N 3.03Å
390	N	94.6	Very high	94.6	Very high	95 Å²	95	39.2 Å²	39.2	51%	0.508	20%	0.204	S	C	.	.	H	α-helix	trans	-90.7	-29.6	-174.3	-66.9	-84.1	0	0	0	113.3	F386	F386-N390 VanDerWaalsContact CD2-ND2 3.27Å; F386-N390 WeakPolarHBondContact CD2-ND2 3.47Å; F386-N390 VanDerWaalsContact CE2-ND2 3.32Å; F386-N390 WeakPolarHBondContact CE2-ND2 3.33Å; F386-N390 WeakPolarHBondContact O-CB 3.31Å; F386-N390 PolarHBondContact O-N 3.25Å; F386-N390 VanDerWaalsContact O-N 3.07Å; F386-N390 PolarHBondContact O-ND2 2.93Å
391	Y	94.4	Very high	94.8	Very high	155 Å²	155	41.5 Å²	41.5	61%	0.608	21%	0.214	S	C	*	.	H	α-helix	trans	-130.2	1	-171.6	-53.8	-79.1	0	0	0	113.7	F386 L387 S395	F386-Y391 HydrophobicContact CE1-CE2 4.06Å; L387-Y391 HydrophobicContact CD2-CD2 4.24Å; L387-Y391 CarbonylContact O-C 3.2Å; L387-Y391 WeakPolarHBondContact O-CA 3.49Å; L387-Y391 WeakPolarHBondContact O-CB 3.16Å; L387-Y391 PolarHBondContact O-N 3.25Å; Y391-S395 VanDerWaalsContact CB-CB 3.46Å
392	G	92.7	Very high	95	Very high	30 Å²	30	47.1 Å²	47.1	31%	0.309	24%	0.239	S	C	.	.	H	α-helix	trans	74	177.6	178.5	0	0	0	0	0	114.3	L387 Y388 A394 S395	L387-G392 PolarHBondContact O-N 2.84Å; Y388-G392 WeakPolarHBondContact O-CA 3.36Å; Y388-G392 PolarHBondContact O-N 2.94Å; G392-A394 VanDerWaalsContact C-N 3.28Å; G392-A394 PolarHBondContact O-N 3.02Å; G392-S395 WeakPolarHBondContact O-CB 3.34Å; G392-S395 PolarHBondContact O-N 3Å; G392-S395 PolarHBondContact O-OG 3.32Å
393	L	92.2	Very high	95.2	Very high	9 Å²	9	47.5 Å²	47.5	5%	0.047	24%	0.241	C	C	.	.	H	α-helix	trans	-58.1	-38.1	180	177.8	62.7	0	0	0	113.2	F257 I264 F268 M325 Y388 S395 I396	F257-L393 HydrophobicContact CE2-CD1 4Å; I264-L393 HydrophobicContact CD1-CD1 3.66Å; I264-L393 HydrophobicContact CG1-CD1 3.92Å; I264-L393 HydrophobicContact CG2-CD1 3.77Å; I264-L393 HydrophobicContact CG2-CD2 4.13Å; F268-L393 HydrophobicContact CB-CD2 4.44Å; F268-L393 HydrophobicContact CD1-CD2 3.57Å; F268-L393 HydrophobicContact CD2-CB 4.14Å; F268-L393 HydrophobicContact CD2-CD2 3.83Å; F268-L393 HydrophobicContact CE1-CD2 3.62Å; F268-L393 HydrophobicContact CE2-CB 4.29Å; F268-L393 HydrophobicContact CE2-CD2 3.87Å; F268-L393 HydrophobicContact CG-CD2 3.68Å; F268-L393 HydrophobicContact CZ-CD2 3.77Å; M325-L393 HydrophobicContact CE-CD2 3.68Å; Y388-L393 HydrophobicContact CD2-CB 4.34Å; Y388-L393 HydrophobicContact CE2-CB 4.04Å; Y388-L393 HydrophobicContact CE2-CD1 4.47Å; L393-S395 PolarHBondContact O-N 3.18Å; L393-I396 PolarHBondContact O-N 2.91Å; L393-I396 VanDerWaalsContact O-N 3.12Å
394	A	95.1	Very high	95.3	Very high	40 Å²	40	44.5 Å²	44.5	33%	0.331	23%	0.226	S	C	.	.	H	α-helix	trans	-58.3	-32.6	-176.9	0	0	0	0	0	112.3	A323 G392 I396 G397 L398	A323-A394 WeakPolarHBondContact O-CB 3.39Å; G392-A394 VanDerWaalsContact C-N 3.28Å; G392-A394 PolarHBondContact O-N 3.02Å; A394-I396 VanDerWaalsContact C-N 3.33Å; A394-I396 PolarHBondContact O-N 3.25Å; A394-G397 PolarHBondContact O-N 3.12Å; A394-L398 WeakPolarHBondContact O-CB 3.3Å; A394-L398 VanDerWaalsContact O-CG 3.28Å; A394-L398 WeakPolarHBondContact O-CG 3.41Å; A394-L398 PolarHBondContact O-N 3.34Å
395	S	95.3	Very high	95.5	Very high	16 Å²	16	47.1 Å²	47.1	11%	0.112	24%	0.239	C	C	.	.	H	α-helix	trans	-60.1	-40.6	178.4	69.8	0	0	0	0	112.9	L387 Y391 G392 L393 L398 I399	L387-S395 PolarHBondContact O-OG 2.9Å; Y391-S395 VanDerWaalsContact CB-CB 3.46Å; G392-S395 WeakPolarHBondContact O-CB 3.34Å; G392-S395 PolarHBondContact O-N 3Å; G392-S395 PolarHBondContact O-OG 3.32Å; L393-S395 PolarHBondContact O-N 3.18Å; S395-L398 PolarHBondContact O-N 2.86Å; S395-I399 WeakPolarHBondContact O-CB 3.21Å; S395-I399 WeakPolarHBondContact O-CD1 3.28Å; S395-I399 WeakPolarHBondContact O-CG1 3.21Å; S395-I399 PolarHBondContact O-N 2.73Å
396	I	94.8	Very high	95.7	Very high	3 Å²	3	51.8 Å²	51.8	2%	0.015	27%	0.267	C	S	.	.	H	α-helix	trans	-65.2	-47.8	-179.7	-58	176.9	0	0	0	109.5	I256 F257 I264 L387 L393 A394 I399 E400	I256-I396 HydrophobicContact CG2-CG2 4.33Å; F257-I396 HydrophobicContact CB-CG2 3.97Å; F257-I396 HydrophobicContact CD2-CG2 3.93Å; F257-I396 HydrophobicContact CG-CG2 4.45Å; I264-I396 HydrophobicContact CD1-CD1 4.47Å; L387-I396 HydrophobicContact CB-CG1 4.21Å; L393-I396 PolarHBondContact O-N 2.91Å; L393-I396 VanDerWaalsContact O-N 3.12Å; A394-I396 VanDerWaalsContact C-N 3.33Å; A394-I396 PolarHBondContact O-N 3.25Å; I396-I399 PolarHBondContact O-N 2.97Å; I396-E400 PolarHBondContact O-N 2.97Å
397	G	95.9	Very high	95.8	Very high	1 Å²	1	47.8 Å²	47.8	1%	0.01	25%	0.251	C	S	.	.	H	α-helix	trans	-65.4	-40.7	178.1	0	0	0	0	0	113.3	G319 A394 E400 F401	G319-G397 CarbonylContact C-O 3.58Å; G319-G397 WeakPolarHBondContact CA-O 3.42Å; G319-G397 CarbonylContact O-C 3.59Å; G319-G397 WeakPolarHBondContact O-CA 3.09Å; A394-G397 PolarHBondContact O-N 3.12Å; G397-E400 WeakPolarHBondContact O-CB 3.4Å; G397-E400 PolarHBondContact O-N 3.24Å; G397-F401 PolarHBondContact O-N 3.26Å
398	L	97.3	Very high	95.8	Very high	58 Å²	58	49 Å²	49	30%	0.304	26%	0.255	S	S	.	.	H	α-helix	trans	-65.9	-42.8	177.3	-72.2	174.9	0	0	0	111.8	A323 A394 S395 E400 F401 F402	A323-L398 HydrophobicContact CB-CD2 3.92Å; A323-L398 HydrophobicContact CB-CG 3.84Å; A394-L398 WeakPolarHBondContact O-CB 3.3Å; A394-L398 VanDerWaalsContact O-CG 3.28Å; A394-L398 WeakPolarHBondContact O-CG 3.41Å; A394-L398 PolarHBondContact O-N 3.34Å; S395-L398 PolarHBondContact O-N 2.86Å; L398-E400 VanDerWaalsContact C-N 3.29Å; L398-E400 PolarHBondContact O-N 3.16Å; L398-F401 PolarHBondContact O-N 3.27Å; L398-F402 HydrophobicContact CB-CD2 4.35Å; L398-F402 HydrophobicContact CB-CE2 4.38Å; L398-F402 HydrophobicContact CD2-CE2 4.35Å; L398-F402 WeakPolarHBondContact O-CD2 3.41Å; L398-F402 PolarHBondContact O-N 3.32Å
399	I	96.7	Very high	95.9	Very high	67 Å²	67	51.4 Å²	51.4	34%	0.344	27%	0.273	S	S	.	.	H	α-helix	trans	-59.5	-44	174.1	-71.5	165.6	0	0	0	109.9	P253 L387 S395 I396 F401 F402 V403	P253-I399 HydrophobicContact CB-CG2 4.41Å; P253-I399 HydrophobicContact CG-CG2 4.26Å; L387-I399 HydrophobicContact CD1-CD1 3.7Å; L387-I399 HydrophobicContact CD2-CD1 3.72Å; L387-I399 HydrophobicContact CG-CD1 4.36Å; S395-I399 WeakPolarHBondContact O-CB 3.21Å; S395-I399 WeakPolarHBondContact O-CD1 3.28Å; S395-I399 WeakPolarHBondContact O-CG1 3.21Å; S395-I399 PolarHBondContact O-N 2.73Å; I396-I399 PolarHBondContact O-N 2.97Å; I399-F401 PolarHBondContact O-N 2.85Å; I399-F402 PolarHBondContact O-N 2.97Å; I399-V403 HydrophobicContact CG2-CG2 4.18Å; I399-V403 VanDerWaalsContact O-CB 3.3Å; I399-V403 WeakPolarHBondContact O-CB 3.37Å; I399-V403 VanDerWaalsContact O-CG2 3.22Å; I399-V403 WeakPolarHBondContact O-CG2 3.25Å; I399-V403 PolarHBondContact O-N 3.25Å
400	E	96.9	Very high	96	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-59.2	-46.1	175.6	-178	161.9	178.6	0	0	112.3	P253 S254 T315 Q322 I396 G397 L398 N404	P253-E400 VanDerWaalsContact CB-CA 3.47Å; P253-E400 HydrophobicContact CB-CB 3.62Å; P253-E400 HydrophobicContact CB-CG 4.01Å; S254-E400 WeakPolarHBondContact CA-OE2 3.47Å; S254-E400 WeakPolarHBondContact CB-OE1 3.08Å; S254-E400 VanDerWaalsContact OG-CD 3.3Å; S254-E400 PolarHBondContact OG-OE1 3.41Å; T315-E400 HydrophobicContact CG2-CG 4.13Å; T315-E400 VanDerWaalsContact CG2-OE1 3.27Å; T315-E400 WeakPolarHBondContact CG2-OE1 3.25Å; Q322-E400 PolarHBondContact OE1-OE2 3.4Å; Q322-E400 VanDerWaalsContact OE1-OE2 3.04Å; I396-E400 PolarHBondContact O-N 2.97Å; G397-E400 WeakPolarHBondContact O-CB 3.4Å; G397-E400 PolarHBondContact O-N 3.24Å; L398-E400 VanDerWaalsContact C-N 3.29Å; L398-E400 PolarHBondContact O-N 3.16Å; E400-N404 VanDerWaalsContact O-CB 3.28Å; E400-N404 WeakPolarHBondContact O-CB 3.47Å; E400-N404 PolarHBondContact O-N 3.47Å; E400-N404 VanDerWaalsContact O-N 3.09Å; E400-N404 PolarHBondContact O-ND2 2.92Å
401	F	97.9	Very high	96	Very high	49 Å²	49	48.7 Å²	48.7	22%	0.215	25%	0.252	C	S	.	.	H	α-helix	trans	-60.9	-55.1	176.2	172.7	-105.8	0	0	0	112.2	A316 L320 G397 L398 I399 V403 N404 I405	A316-F401 HydrophobicContact CB-CD2 4.25Å; A316-F401 WeakPolarHBondContact O-CD2 3.48Å; L320-F401 HydrophobicContact CB-CB 4.42Å; L320-F401 HydrophobicContact CB-CD2 3.84Å; L320-F401 HydrophobicContact CB-CE2 4.39Å; L320-F401 HydrophobicContact CB-CG 4.23Å; L320-F401 HydrophobicContact CD1-CD1 4.48Å; L320-F401 HydrophobicContact CD1-CD2 4.44Å; L320-F401 HydrophobicContact CD1-CG 4.34Å; L320-F401 HydrophobicContact CD2-CE2 4.32Å; G397-F401 PolarHBondContact O-N 3.26Å; L398-F401 PolarHBondContact O-N 3.27Å; I399-F401 PolarHBondContact O-N 2.85Å; F401-V403 PolarHBondContact O-N 3.15Å; F401-N404 PolarHBondContact O-N 3.21Å; F401-I405 HydrophobicContact CE1-CG2 4.44Å; F401-I405 HydrophobicContact CE2-CB 4.47Å; F401-I405 WeakPolarHBondContact O-CB 3.45Å; F401-I405 WeakPolarHBondContact O-CG2 3.45Å; F401-I405 PolarHBondContact O-N 3.39Å
402	F	97.8	Very high	95.9	Very high	121 Å²	121	44.5 Å²	44.5	53%	0.531	24%	0.24	S	C	.	.	H	α-helix	trans	-64.4	-41.6	-174.4	-79.1	-64.8	0	0	0	112.4	L398 I399 I405 V406	L398-F402 HydrophobicContact CB-CD2 4.35Å; L398-F402 HydrophobicContact CB-CE2 4.38Å; L398-F402 HydrophobicContact CD2-CE2 4.35Å; L398-F402 WeakPolarHBondContact O-CD2 3.41Å; L398-F402 PolarHBondContact O-N 3.32Å; I399-F402 PolarHBondContact O-N 2.97Å; F402-I405 WeakPolarHBondContact O-CG2 3.44Å; F402-V406 WeakPolarHBondContact O-CB 3.47Å; F402-V406 VanDerWaalsContact O-CG2 3.22Å; F402-V406 WeakPolarHBondContact O-CG2 3.48Å; F402-V406 PolarHBondContact O-N 2.96Å
403	V	97.4	Very high	95.9	Very high	42 Å²	42	51 Å²	51	26%	0.255	26%	0.257	S	S	.	.	H	α-helix	trans	-65.4	-47.9	177.8	172.8	0	0	0	0	110.3	I249 P253 I399 F401 V406 V407	I249-V403 HydrophobicContact CG2-CG1 3.54Å; I249-V403 WeakPolarHBondContact O-CG1 3.38Å; P253-V403 HydrophobicContact CG-CB 4.12Å; P253-V403 HydrophobicContact CG-CG1 4.18Å; P253-V403 HydrophobicContact CG-CG2 4.33Å; I399-V403 HydrophobicContact CG2-CG2 4.18Å; I399-V403 VanDerWaalsContact O-CB 3.3Å; I399-V403 WeakPolarHBondContact O-CB 3.37Å; I399-V403 VanDerWaalsContact O-CG2 3.22Å; I399-V403 WeakPolarHBondContact O-CG2 3.25Å; I399-V403 PolarHBondContact O-N 3.25Å; F401-V403 PolarHBondContact O-N 3.15Å; V403-V406 PolarHBondContact O-N 2.98Å; V403-V407 WeakPolarHBondContact O-CG2 3.26Å; V403-V407 PolarHBondContact O-N 3.19Å; V403-V407 VanDerWaalsContact O-N 3.11Å
404	N	97.7	Very high	95.7	Very high	1 Å²	1	54.2 Å²	54.2	1%	0.005	27%	0.268	C	S	.	.	H	α-helix	trans	-72.1	-33.6	-176.6	-77.2	-79.2	0	0	0	113	A250 I312 T315 A316 E400 F401 V407 F408	A250-N404 WeakPolarHBondContact CB-OD1 3.45Å; A250-N404 PolarHBondContact O-ND2 2.88Å; A250-N404 PolarHBondContact O-OD1 2.93Å; I312-N404 HydrophobicContact CG2-CB 4.15Å; I312-N404 WeakPolarHBondContact CG2-O 3.2Å; T315-N404 HydrophobicContact CG2-CB 4.46Å; A316-N404 HydrophobicContact CB-CB 3.81Å; E400-N404 VanDerWaalsContact O-CB 3.28Å; E400-N404 WeakPolarHBondContact O-CB 3.47Å; E400-N404 PolarHBondContact O-N 3.47Å; E400-N404 VanDerWaalsContact O-N 3.09Å; E400-N404 PolarHBondContact O-ND2 2.92Å; F401-N404 PolarHBondContact O-N 3.21Å; N404-V407 PolarHBondContact O-N 3.48Å; N404-F408 WeakPolarHBondContact O-CB 3.28Å; N404-F408 PolarHBondContact O-N 3.29Å
405	I	97.7	Very high	95.3	Very high	55 Å²	55	54.9 Å²	54.9	28%	0.282	26%	0.264	S	S	.	.	H	α-helix	trans	-68.6	-38.1	176.6	-161.5	63.9	0	0	0	111.6	A316 F401 F402 F408 V409	A316-I405 HydrophobicContact CB-CB 4.44Å; F401-I405 HydrophobicContact CE1-CG2 4.44Å; F401-I405 HydrophobicContact CE2-CB 4.47Å; F401-I405 WeakPolarHBondContact O-CB 3.45Å; F401-I405 WeakPolarHBondContact O-CG2 3.45Å; F401-I405 PolarHBondContact O-N 3.39Å; F402-I405 WeakPolarHBondContact O-CG2 3.44Å; I405-F408 HydrophobicContact CD1-CD1 4.42Å; I405-F408 WeakPolarHBondContact O-CB 3.48Å; I405-F408 PolarHBondContact O-N 2.9Å; I405-V409 VanDerWaalsContact O-CG2 3.31Å; I405-V409 WeakPolarHBondContact O-CG2 3.48Å; I405-V409 PolarHBondContact O-N 2.63Å
406	V	97.6	Very high	94.7	Very high	98 Å²	98	58.8 Å²	58.8	59%	0.594	28%	0.283	S	S	*	.	H	α-helix	trans	-63.4	-45.5	174.7	169.6	0	0	0	0	110.4	F402 V403 F408 V409 Y410	F402-V406 WeakPolarHBondContact O-CB 3.47Å; F402-V406 VanDerWaalsContact O-CG2 3.22Å; F402-V406 WeakPolarHBondContact O-CG2 3.48Å; F402-V406 PolarHBondContact O-N 2.96Å; V403-V406 PolarHBondContact O-N 2.98Å; V406-F408 VanDerWaalsContact C-N 3.34Å; V406-F408 PolarHBondContact O-N 3.23Å; V406-V409 PolarHBondContact O-N 3.26Å; V406-Y410 WeakPolarHBondContact O-CB 3.49Å; V406-Y410 PolarHBondContact O-N 3.42Å
407	V	96.8	Very high	94	Very high	15 Å²	15	59.6 Å²	59.6	9%	0.091	29%	0.29	C	S	.	.	H	α-helix	trans	-63.8	-41.1	176.1	176.9	0	0	0	0	111.1	I246 I249 A250 I312 V403 N404 Y410 L411	I246-V407 HydrophobicContact CG2-CG1 4.23Å; I249-V407 HydrophobicContact CG2-CG2 3.99Å; A250-V407 HydrophobicContact CB-CG1 4.38Å; A250-V407 HydrophobicContact CB-CG2 4.49Å; I312-V407 HydrophobicContact CD1-CG1 3.93Å; I312-V407 HydrophobicContact CG2-CB 4.34Å; I312-V407 HydrophobicContact CG2-CG1 4.26Å; V403-V407 WeakPolarHBondContact O-CG2 3.26Å; V403-V407 PolarHBondContact O-N 3.19Å; V403-V407 VanDerWaalsContact O-N 3.11Å; N404-V407 PolarHBondContact O-N 3.48Å; V407-Y410 PolarHBondContact O-N 2.98Å; V407-L411 HydrophobicContact CG1-CD1 4Å; V407-L411 HydrophobicContact CG1-CG 4.35Å; V407-L411 WeakPolarHBondContact O-CB 3.5Å; V407-L411 VanDerWaalsContact O-CG 3.31Å; V407-L411 WeakPolarHBondContact O-CG 3.26Å; V407-L411 PolarHBondContact O-N 3.22Å
408	F	96.8	Very high	93.2	Very high	50 Å²	50	62.6 Å²	62.6	22%	0.219	31%	0.305	C	S	.	.	H	α-helix	trans	-59.6	-51.7	177.3	-177.9	-90.8	0	0	0	111.6	L309 I312 G313 N404 I405 V406 Y410 L411 L412	L309-F408 HydrophobicContact CD1-CD2 3.54Å; L309-F408 HydrophobicContact CD1-CE2 3.57Å; L309-F408 HydrophobicContact CD1-CG 4.1Å; L309-F408 HydrophobicContact CD1-CZ 4.11Å; L309-F408 HydrophobicContact CD2-CE2 4.38Å; L309-F408 HydrophobicContact CD2-CZ 4.49Å; L309-F408 HydrophobicContact CG-CD2 4.01Å; L309-F408 HydrophobicContact CG-CE2 3.55Å; L309-F408 HydrophobicContact CG-CZ 4.12Å; L309-F408 WeakPolarHBondContact O-CD2 3.14Å; L309-F408 VanDerWaalsContact O-CE2 3.31Å; L309-F408 WeakPolarHBondContact O-CE2 3.22Å; I312-F408 HydrophobicContact CG2-CB 4.02Å; G313-F408 VanDerWaalsContact CA-CD2 3.49Å; N404-F408 WeakPolarHBondContact O-CB 3.28Å; N404-F408 PolarHBondContact O-N 3.29Å; I405-F408 HydrophobicContact CD1-CD1 4.42Å; I405-F408 WeakPolarHBondContact O-CB 3.48Å; I405-F408 PolarHBondContact O-N 2.9Å; V406-F408 VanDerWaalsContact C-N 3.34Å; V406-F408 PolarHBondContact O-N 3.23Å; F408-Y410 VanDerWaalsContact C-N 3.35Å; F408-Y410 PolarHBondContact O-N 2.88Å; F408-L411 PolarHBondContact O-N 3.12Å; F408-L412 HydrophobicContact CE1-CD2 4.28Å; F408-L412 WeakPolarHBondContact O-CB 3.33Å; F408-L412 PolarHBondContact O-N 3.03Å
409	V	96.4	Very high	92.1	Very high	83 Å²	83	63.1 Å²	63.1	50%	0.503	31%	0.311	S	S	.	.	H	α-helix	trans	-61.6	-43.5	179	171.6	0	0	0	0	110.9	I405 V406 L411 L412 Y413	I405-V409 VanDerWaalsContact O-CG2 3.31Å; I405-V409 WeakPolarHBondContact O-CG2 3.48Å; I405-V409 PolarHBondContact O-N 2.63Å; V406-V409 PolarHBondContact O-N 3.26Å; V409-L411 PolarHBondContact O-N 3.42Å; V409-L412 PolarHBondContact O-N 2.96Å; V409-Y413 WeakPolarHBondContact O-CB 3.4Å; V409-Y413 PolarHBondContact O-N 3Å
410	Y	95.3	Very high	90.6	Very high	113 Å²	113	66 Å²	66	44%	0.443	32%	0.323	S	S	.	.	H	α-helix	trans	-58.9	-44.8	175.7	167.6	-105.5	0	0	0	112.4	V406 V407 F408 R414	V406-Y410 WeakPolarHBondContact O-CB 3.49Å; V406-Y410 PolarHBondContact O-N 3.42Å; V407-Y410 PolarHBondContact O-N 2.98Å; F408-Y410 VanDerWaalsContact C-N 3.35Å; F408-Y410 PolarHBondContact O-N 2.88Å; Y410-R414 WeakPolarHBondContact O-CB 3.36Å; Y410-R414 PolarHBondContact O-N 2.77Å
411	L	93.9	Very high	89.1	Confident	16 Å²	16	74.6 Å²	74.6	8%	0.084	36%	0.356	C	S	.	.	H	α-helix	trans	-68.4	-39.4	178.2	-72.4	177.4	0	0	0	112.3	I246 L308 L309 I312 V407 F408 V409 R414 Q415	I246-L411 HydrophobicContact CD1-CD2 3.85Å; L308-L411 HydrophobicContact CD2-CD1 4.18Å; L308-L411 HydrophobicContact CG-CD1 4.29Å; L309-L411 HydrophobicContact CD1-CB 3.98Å; I312-L411 HydrophobicContact CD1-CD1 3.48Å; I312-L411 VanDerWaalsContact CD1-CD1 3.48Å; V407-L411 HydrophobicContact CG1-CD1 4Å; V407-L411 HydrophobicContact CG1-CG 4.35Å; V407-L411 WeakPolarHBondContact O-CB 3.5Å; V407-L411 VanDerWaalsContact O-CG 3.31Å; V407-L411 WeakPolarHBondContact O-CG 3.26Å; V407-L411 PolarHBondContact O-N 3.22Å; F408-L411 PolarHBondContact O-N 3.12Å; V409-L411 PolarHBondContact O-N 3.42Å; L411-R414 PolarHBondContact O-N 3.42Å; L411-Q415 WeakPolarHBondContact O-CG 3.15Å; L411-Q415 PolarHBondContact O-N 3.05Å
412	L	93	Very high	87.5	Confident	67 Å²	67	80 Å²	80	35%	0.351	38%	0.382	S	S	.	.	H	α-helix	trans	-64	-50.7	178.3	-176.2	68	0	0	0	111.4	L309 F408 V409 R414 Q415 L416	L309-L412 HydrophobicContact CD1-CB 4.36Å; L309-L412 HydrophobicContact CD2-CD1 3.94Å; F408-L412 HydrophobicContact CE1-CD2 4.28Å; F408-L412 WeakPolarHBondContact O-CB 3.33Å; F408-L412 PolarHBondContact O-N 3.03Å; V409-L412 PolarHBondContact O-N 2.96Å; L412-R414 PolarHBondContact O-N 3.2Å; L412-Q415 PolarHBondContact O-N 3.13Å; L412-L416 HydrophobicContact CG-CD1 4.33Å; L412-L416 WeakPolarHBondContact O-CG 3.4Å; L412-L416 PolarHBondContact O-N 3.46Å
413	Y	92.3	Very high	85.7	Confident	167 Å²	167	82.7 Å²	82.7	66%	0.655	39%	0.393	S	S	*	.	H	α-helix	trans	-55.7	-39.8	176.5	177.6	-100.5	0	0	0	111.8	V409 L416 S417	V409-Y413 WeakPolarHBondContact O-CB 3.4Å; V409-Y413 PolarHBondContact O-N 3Å; Y413-L416 PolarHBondContact O-N 2.91Å; Y413-S417 WeakPolarHBondContact O-CB 3.43Å; Y413-S417 PolarHBondContact O-N 3.04Å; Y413-S417 PolarHBondContact O-OG 3.47Å
414	R	88.5	Confident	83.5	Confident	76 Å²	76	90.9 Å²	90.9	29%	0.287	43%	0.428	S	S	.	.	H	α-helix	trans	-72.6	-30.7	178.9	-166	170	175.7	-122.2	-12.1	113.7	R242 Y410 L411 L412 S417 N418	R242-R414 VanDerWaalsContact CZ-NH1 3.34Å; Y410-R414 WeakPolarHBondContact O-CB 3.36Å; Y410-R414 PolarHBondContact O-N 2.77Å; L411-R414 PolarHBondContact O-N 3.42Å; L412-R414 PolarHBondContact O-N 3.2Å; R414-S417 WeakPolarHBondContact CA-OG 3.12Å; R414-S417 PolarHBondContact O-OG 3.39Å; R414-N418 VanDerWaalsContact O-CG 3.27Å; R414-N418 PolarHBondContact O-N 3.23Å; R414-N418 PolarHBondContact O-ND2 3.02Å
415	Q	85.1	Confident	82.8	Confident	54 Å²	54	95.4 Å²	95.4	25%	0.252	45%	0.45	S	S	.	.	H	α-helix	trans	-68	-46.9	173.3	-77.3	-178	3.5	0	0	110.4	K305 L411 L412 N418 T419	K305-Q415 PolarHBondContact O-NE2 3.28Å; L411-Q415 WeakPolarHBondContact O-CG 3.15Å; L411-Q415 PolarHBondContact O-N 3.05Å; L412-Q415 PolarHBondContact O-N 3.13Å; Q415-N418 PolarHBondContact O-N 3.18Å; Q415-T419 PolarHBondContact O-N 2.96Å; Q415-T419 VanDerWaalsContact O-N 3.12Å; Q415-T419 PolarHBondContact O-OG1 2.87Å
416	L	83.2	Confident	82	Confident	98 Å²	98	97.5 Å²	97.5	51%	0.513	46%	0.458	S	S	.	.	H	α-helix	trans	-60.4	-50.2	179.2	-67.4	170	0	0	0	112	L412 Y413 N418 T419 E420	L412-L416 HydrophobicContact CG-CD1 4.33Å; L412-L416 WeakPolarHBondContact O-CG 3.4Å; L412-L416 PolarHBondContact O-N 3.46Å; Y413-L416 PolarHBondContact O-N 2.91Å; L416-N418 VanDerWaalsContact C-N 3.3Å; L416-N418 PolarHBondContact O-N 3.41Å; L416-T419 WeakPolarHBondContact O-CB 3.42Å; L416-T419 PolarHBondContact O-N 3.37Å; L416-E420 PolarHBondContact O-N 3.03Å
417	S	80.4	Confident	81.1	Confident	21 Å²	21	97.5 Å²	97.5	15%	0.147	45%	0.451	C	S	.	.	H	α-helix	trans	-62.4	-31.7	179.3	50.3	0	0	0	0	114.2	Y413 R414 R421	Y413-S417 WeakPolarHBondContact O-CB 3.43Å; Y413-S417 PolarHBondContact O-N 3.04Å; Y413-S417 PolarHBondContact O-OG 3.47Å; R414-S417 WeakPolarHBondContact CA-OG 3.12Å; R414-S417 PolarHBondContact O-OG 3.39Å; S417-R421 WeakPolarHBondContact O-CG 3.48Å; S417-R421 PolarHBondContact O-N 3.36Å
418	N	78.9	Confident	80.2	Confident	63 Å²	63	102.4 Å²	102.4	34%	0.337	47%	0.472	S	S	.	.	H	α-helix	trans	-73.3	-33.2	173.3	-73.8	-35.6	0	0	0	112.2	R414 Q415 L416 Q422	R414-N418 VanDerWaalsContact O-CG 3.27Å; R414-N418 PolarHBondContact O-N 3.23Å; R414-N418 PolarHBondContact O-ND2 3.02Å; Q415-N418 PolarHBondContact O-N 3.18Å; L416-N418 VanDerWaalsContact C-N 3.3Å; L416-N418 PolarHBondContact O-N 3.41Å; N418-Q422 WeakPolarHBondContact O-CG 3.5Å; N418-Q422 PolarHBondContact O-N 2.95Å
419	T	73.9	Confident	79.2	Confident	69 Å²	69	105.6 Å²	105.6	42%	0.423	49%	0.488	S	S	.	.	H	α-helix	trans	-69.5	-35.6	175.8	-60.3	0	0	0	0	111.4	Q415 L416 Q422 K423	Q415-T419 PolarHBondContact O-N 2.96Å; Q415-T419 VanDerWaalsContact O-N 3.12Å; Q415-T419 PolarHBondContact O-OG1 2.87Å; L416-T419 WeakPolarHBondContact O-CB 3.42Å; L416-T419 PolarHBondContact O-N 3.37Å; T419-Q422 PolarHBondContact O-N 3.48Å; T419-K423 WeakPolarHBondContact O-CG 3.43Å; T419-K423 PolarHBondContact O-N 3.34Å
420	E	65.9	Low	78	Confident	127 Å²	127	107.1 Å²	107.1	59%	0.593	49%	0.487	S	S	*	.	H	α-helix	trans	-65.5	-47.5	174.2	-71.1	172.3	167	0	0	111.6	L416 Q422 K423 E424	L416-E420 PolarHBondContact O-N 3.03Å; E420-Q422 PolarHBondContact O-N 2.84Å; E420-Q422 VanDerWaalsContact O-N 3.14Å; E420-K423 PolarHBondContact O-N 2.77Å; E420-E424 PolarHBondContact O-N 3.22Å
421	R	65.6	Low	76.8	Confident	182 Å²	182	106.7 Å²	106.7	69%	0.687	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.1	-14.1	175.7	-71.5	-174.6	-155.8	-167.6	2.1	115.6	S417	S417-R421 WeakPolarHBondContact O-CG 3.48Å; S417-R421 PolarHBondContact O-N 3.36Å
422	Q	63.6	Low	75.5	Confident	163 Å²	163	113.7 Å²	113.7	76%	0.762	52%	0.521	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.4	-11.6	174.6	-77.4	-176.8	-27.3	0	0	112.4	N418 T419 E420	N418-Q422 WeakPolarHBondContact O-CG 3.5Å; N418-Q422 PolarHBondContact O-N 2.95Å; T419-Q422 PolarHBondContact O-N 3.48Å; E420-Q422 PolarHBondContact O-N 2.84Å; E420-Q422 VanDerWaalsContact O-N 3.14Å
423	K	59.8	Low	74	Confident	177 Å²	177	117.6 Å²	117.6	77%	0.77	54%	0.535	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.1	-26.6	175.5	-73.5	177.5	176.7	-176.2	0	112.3	T419 E420	T419-K423 WeakPolarHBondContact O-CG 3.43Å; T419-K423 PolarHBondContact O-N 3.34Å; E420-K423 PolarHBondContact O-N 2.77Å
424	E	51	Low	72.4	Confident	214 Å²	214	113.1 Å²	113.1	100%	1	53%	0.525	S	S	*	.			trans	-75.4	0	161.9	-64.3	178.3	167.2	0	0	110.6	E420	E420-E424 PolarHBondContact O-N 3.22Å

Retrieved 424 of 424 residues in 650.4 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).