A0A087XLT1_POEFO Loading...

High affinity choline transporter 1

High-affinity Na(+)-coupled choline transmembrane symporter. Functions as an electrogenic, voltage-dependent transporter with variable charge/choline stoichiometry. Choline uptake and choline-induced current is also Cl(-)-dependent where Cl(-) is likely a regulatory ion rather than cotransported ion. Plays a critical role in acetylcholine (ACh) synthesis by taking up the substrate choline from the synaptic cleft into the presynaptic nerve terminals after neurotransmitter release. SLC5A7/CHT1-mediated choline high-affinity transport in cholinergic neurons is the rate-limiting step for production of ACh, thereby facilitating communication by subsequent action potentials. Localized predominantly in presynaptic terminal intracellular organelles, and translocated to the plasma membrane in active form in response to neuronal activity.

AlphaFold DB , UniProt , Accession A0A087XLT1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 590 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.7	Very low	65.7	Low	205 Å²	205	80.9 Å²	80.9	100%	1.01	44%	0.439	S	S	*	.				0	74.8	0	-75.6	-163.2	-77.5	0	0	109.8
2	T	47.8	Very low	66.8	Low	109 Å²	109	80.6 Å²	80.6	67%	0.669	44%	0.441	S	S	*	.			trans	-101.9	93.6	160.1	38.7	0	0	0	0	105	H4	T2-H4 PolarHBondContact O-N 2.93Å; T2-H4 VanDerWaalsContact O-N 3.1Å
3	I	56.9	Low	67.9	Low	94 Å²	94	83.3 Å²	83.3	48%	0.482	45%	0.454	S	S	.	.			trans	-58.9	120	175.2	-62.2	172.9	0	0	0	106.3	V5 L8	I3-V5 WeakPolarHBondContact O-CG2 3.16Å; I3-V5 PolarHBondContact O-N 3.15Å; I3-L8 HydrophobicContact CG2-CD2 4.34Å
4	H	67.4	Low	68.5	Low	78 Å²	78	79.4 Å²	79.4	36%	0.361	43%	0.431	S	S	.	.			trans	-69	83.6	171.6	-68.5	-73.3	0	0	0	108.2	T2 E6 G7 L8 F336	T2-H4 PolarHBondContact O-N 2.93Å; T2-H4 VanDerWaalsContact O-N 3.1Å; H4-E6 PolarHBondContact O-N 2.88Å; H4-E6 VanDerWaalsContact O-N 3.16Å; H4-G7 WeakPolarHBondContact O-CA 3.14Å; H4-G7 PolarHBondContact O-N 3.4Å; H4-L8 PolarHBondContact O-N 3.33Å; H4-F336 HydrophobicContact CB-CE1 4.36Å; H4-F336 HydrophobicContact CB-CZ 4.35Å
5	V	73.1	Confident	69	Low	98 Å²	98	75.6 Å²	75.6	59%	0.594	41%	0.408	S	S	*	.	H	α-helix	trans	-53.4	-39.2	-175.2	-179.5	0	0	0	0	110.8	I3 L8 V9	I3-V5 WeakPolarHBondContact O-CG2 3.16Å; I3-V5 PolarHBondContact O-N 3.15Å; V5-L8 PolarHBondContact O-N 3.19Å; V5-V9 HydrophobicContact CG1-CG2 4.39Å; V5-V9 WeakPolarHBondContact O-CB 3.33Å; V5-V9 WeakPolarHBondContact O-CG2 3.15Å; V5-V9 PolarHBondContact O-N 2.89Å
6	E	70.8	Confident	69.9	Low	118 Å²	118	76.2 Å²	76.2	55%	0.551	42%	0.415	S	S	*	.	H	α-helix	trans	-62.9	-43.2	176.7	-59.2	-176.2	176.2	0	0	112.6	H4 V9 A10 F336	H4-E6 PolarHBondContact O-N 2.88Å; H4-E6 VanDerWaalsContact O-N 3.16Å; E6-V9 PolarHBondContact O-N 2.92Å; E6-A10 WeakPolarHBondContact O-CB 3.04Å; E6-A10 PolarHBondContact O-N 2.96Å; E6-F336 HydrophobicContact CB-CD2 4.35Å; E6-F336 HydrophobicContact CB-CE2 3.72Å; E6-F336 HydrophobicContact CB-CZ 4.34Å
7	G	68.5	Low	70.6	Confident	1 Å²	1	76.6 Å²	76.6	1%	0.01	42%	0.416	C	S	.	.	H	α-helix	trans	-66.6	-42.5	176.7	0	0	0	0	0	112.3	H4 V9 A10 I11	H4-G7 WeakPolarHBondContact O-CA 3.14Å; H4-G7 PolarHBondContact O-N 3.4Å; G7-V9 PolarHBondContact O-N 2.88Å; G7-A10 PolarHBondContact O-N 3.49Å; G7-I11 WeakPolarHBondContact O-CG1 3.27Å; G7-I11 PolarHBondContact O-N 2.63Å
8	L	74.1	Confident	71.1	Confident	66 Å²	66	72.4 Å²	72.4	35%	0.346	39%	0.393	S	S	.	.	H	α-helix	trans	-61.4	-45.5	175.2	-177.8	66.9	0	0	0	111.4	I3 H4 V5 A10 I11 V12 V159	I3-L8 HydrophobicContact CG2-CD2 4.34Å; H4-L8 PolarHBondContact O-N 3.33Å; V5-L8 PolarHBondContact O-N 3.19Å; L8-A10 VanDerWaalsContact C-N 3.33Å; L8-A10 PolarHBondContact O-N 2.76Å; L8-I11 PolarHBondContact O-N 3.47Å; L8-V12 HydrophobicContact CD1-CG2 4.4Å; L8-V12 HydrophobicContact CG-CG2 4.48Å; L8-V12 WeakPolarHBondContact O-CB 2.88Å; L8-V12 VanDerWaalsContact O-CG2 3.26Å; L8-V12 WeakPolarHBondContact O-CG2 3.34Å; L8-V12 PolarHBondContact O-N 3.07Å; L8-V159 HydrophobicContact CD1-CG1 4.11Å; L8-V159 HydrophobicContact CD1-CG2 3.99Å
9	V	79	Confident	71.6	Confident	77 Å²	77	71.9 Å²	71.9	47%	0.467	39%	0.39	S	S	.	.	H	α-helix	trans	-61.2	-43.1	177	169.9	0	0	0	0	110.8	V5 E6 G7 V12 L13	V5-V9 HydrophobicContact CG1-CG2 4.39Å; V5-V9 WeakPolarHBondContact O-CB 3.33Å; V5-V9 WeakPolarHBondContact O-CG2 3.15Å; V5-V9 PolarHBondContact O-N 2.89Å; E6-V9 PolarHBondContact O-N 2.92Å; G7-V9 PolarHBondContact O-N 2.88Å; V9-V12 PolarHBondContact O-N 3.33Å; V9-L13 HydrophobicContact CG1-CD1 3.89Å; V9-L13 HydrophobicContact CG1-CG 4.33Å; V9-L13 WeakPolarHBondContact O-CB 3.32Å; V9-L13 VanDerWaalsContact O-CG 3.28Å; V9-L13 WeakPolarHBondContact O-CG 3.24Å; V9-L13 PolarHBondContact O-N 3.48Å
10	A	72.4	Confident	72.2	Confident	37 Å²	37	75.1 Å²	75.1	31%	0.306	40%	0.4	S	S	.	.	H	α-helix	trans	-61.3	-45.1	177.7	0	0	0	0	0	112.5	E6 G7 L8 L13 F14 F336	E6-A10 WeakPolarHBondContact O-CB 3.04Å; E6-A10 PolarHBondContact O-N 2.96Å; G7-A10 PolarHBondContact O-N 3.49Å; L8-A10 VanDerWaalsContact C-N 3.33Å; L8-A10 PolarHBondContact O-N 2.76Å; A10-L13 PolarHBondContact O-N 3.49Å; A10-F14 WeakPolarHBondContact O-CB 3.31Å; A10-F14 PolarHBondContact O-N 3.35Å; A10-F336 HydrophobicContact CB-CB 4.37Å
11	I	73.1	Confident	72.7	Confident	7 Å²	7	72.5 Å²	72.5	4%	0.036	39%	0.387	C	S	.	.	H	α-helix	trans	-64.2	-45.2	176.4	-65.6	174.2	0	0	0	111.1	G7 L8 L13 F14 Y15 L155 I158 V159	G7-I11 WeakPolarHBondContact O-CG1 3.27Å; G7-I11 PolarHBondContact O-N 2.63Å; L8-I11 PolarHBondContact O-N 3.47Å; I11-L13 VanDerWaalsContact C-N 3.34Å; I11-L13 PolarHBondContact O-N 3.06Å; I11-F14 WeakPolarHBondContact O-CB 3.09Å; I11-F14 PolarHBondContact O-N 3.43Å; I11-F14 VanDerWaalsContact O-N 3.16Å; I11-Y15 HydrophobicContact CG2-CD1 4.34Å; I11-Y15 HydrophobicContact CG2-CD2 3.83Å; I11-Y15 HydrophobicContact CG2-CE1 4.1Å; I11-Y15 HydrophobicContact CG2-CE2 3.59Å; I11-Y15 HydrophobicContact CG2-CG 4.22Å; I11-Y15 PolarHBondContact O-N 2.94Å; I11-L155 HydrophobicContact CD1-CD1 3.56Å; I11-L155 HydrophobicContact CG2-CD1 4.3Å; I11-I158 HydrophobicContact CD1-CB 3.85Å; I11-I158 HydrophobicContact CD1-CD1 3.41Å; I11-I158 VanDerWaalsContact CD1-CD1 3.41Å; I11-I158 HydrophobicContact CD1-CG1 4.2Å; I11-I158 HydrophobicContact CD1-CG2 3.58Å; I11-I158 HydrophobicContact CG1-CD1 4.17Å; I11-I158 HydrophobicContact CG1-CG2 4.39Å; I11-V159 HydrophobicContact CD1-CG2 4.21Å
12	V	79.2	Confident	74.5	Confident	77 Å²	77	62.9 Å²	62.9	47%	0.467	34%	0.341	S	S	.	.	H	α-helix	trans	-61.5	-45.6	-179.8	169.7	0	0	0	0	110.3	L8 V9 F14 Y15 V16	L8-V12 HydrophobicContact CD1-CG2 4.4Å; L8-V12 HydrophobicContact CG-CG2 4.48Å; L8-V12 WeakPolarHBondContact O-CB 2.88Å; L8-V12 VanDerWaalsContact O-CG2 3.26Å; L8-V12 WeakPolarHBondContact O-CG2 3.34Å; L8-V12 PolarHBondContact O-N 3.07Å; V9-V12 PolarHBondContact O-N 3.33Å; V12-F14 VanDerWaalsContact C-N 3.3Å; V12-F14 PolarHBondContact O-N 3.29Å; V12-Y15 PolarHBondContact O-N 2.87Å; V12-V16 HydrophobicContact CG1-CG2 4.35Å; V12-V16 WeakPolarHBondContact O-CB 3.25Å; V12-V16 VanDerWaalsContact O-CG2 3.23Å; V12-V16 WeakPolarHBondContact O-CG2 3.37Å; V12-V16 PolarHBondContact O-N 3.5Å
13	L	80.3	Confident	76.1	Confident	116 Å²	116	60 Å²	60	61%	0.607	32%	0.32	S	S	*	.	H	α-helix	trans	-59.7	-42.4	174.9	-73.5	173.2	0	0	0	111.6	V9 A10 I11 V16 L17	V9-L13 HydrophobicContact CG1-CD1 3.89Å; V9-L13 HydrophobicContact CG1-CG 4.33Å; V9-L13 WeakPolarHBondContact O-CB 3.32Å; V9-L13 VanDerWaalsContact O-CG 3.28Å; V9-L13 WeakPolarHBondContact O-CG 3.24Å; V9-L13 PolarHBondContact O-N 3.48Å; A10-L13 PolarHBondContact O-N 3.49Å; I11-L13 VanDerWaalsContact C-N 3.34Å; I11-L13 PolarHBondContact O-N 3.06Å; L13-V16 PolarHBondContact O-N 3.18Å; L13-L17 WeakPolarHBondContact O-CB 3.3Å; L13-L17 PolarHBondContact O-N 3.2Å
14	F	77	Confident	77.4	Confident	29 Å²	29	60.9 Å²	60.9	13%	0.127	32%	0.318	C	S	.	.	H	α-helix	trans	-61.9	-48.9	176.9	-178.3	-102.6	0	0	0	111.9	A10 I11 V12 V16 L17 I18 Q193 C196 A344	A10-F14 WeakPolarHBondContact O-CB 3.31Å; A10-F14 PolarHBondContact O-N 3.35Å; I11-F14 WeakPolarHBondContact O-CB 3.09Å; I11-F14 PolarHBondContact O-N 3.43Å; I11-F14 VanDerWaalsContact O-N 3.16Å; V12-F14 VanDerWaalsContact C-N 3.3Å; V12-F14 PolarHBondContact O-N 3.29Å; F14-V16 PolarHBondContact O-N 3.43Å; F14-L17 WeakPolarHBondContact O-CB 3.24Å; F14-L17 PolarHBondContact O-N 3.37Å; F14-L17 VanDerWaalsContact O-N 3.15Å; F14-I18 HydrophobicContact CD1-CG1 4.38Å; F14-I18 HydrophobicContact CE1-CD1 4.42Å; F14-I18 HydrophobicContact CE1-CG1 3.78Å; F14-I18 HydrophobicContact CE2-CD1 4.09Å; F14-I18 HydrophobicContact CE2-CG1 4.15Å; F14-I18 HydrophobicContact CZ-CD1 3.74Å; F14-I18 HydrophobicContact CZ-CG1 3.6Å; F14-I18 WeakPolarHBondContact O-CG1 3.41Å; F14-I18 PolarHBondContact O-N 3.03Å; F14-Q193 HydrophobicContact CZ-CG 4.39Å; F14-C196 HydrophobicContact CE2-CB 4.15Å; F14-A344 HydrophobicContact CE1-CB 3.54Å; F14-A344 HydrophobicContact CE2-CB 4.19Å; F14-A344 HydrophobicContact CZ-CB 3.19Å
15	Y	76.3	Confident	77.8	Confident	22 Å²	22	57.3 Å²	57.3	9%	0.086	30%	0.301	C	S	.	.	H	α-helix	trans	-64.1	-38.8	177.8	-72.7	-7	0	0	0	112.9	I11 V12 L17 I18 L19 I173 M347	I11-Y15 HydrophobicContact CG2-CD1 4.34Å; I11-Y15 HydrophobicContact CG2-CD2 3.83Å; I11-Y15 HydrophobicContact CG2-CE1 4.1Å; I11-Y15 HydrophobicContact CG2-CE2 3.59Å; I11-Y15 HydrophobicContact CG2-CG 4.22Å; I11-Y15 PolarHBondContact O-N 2.94Å; V12-Y15 PolarHBondContact O-N 2.87Å; Y15-L17 VanDerWaalsContact C-N 3.31Å; Y15-L17 PolarHBondContact O-N 2.67Å; Y15-I18 PolarHBondContact O-N 3.32Å; Y15-L19 VanDerWaalsContact O-CB 3.27Å; Y15-L19 WeakPolarHBondContact O-CB 3.39Å; Y15-L19 PolarHBondContact O-N 3.14Å; Y15-I173 HydrophobicContact CD2-CD1 3.54Å; Y15-I173 HydrophobicContact CD2-CG2 4.33Å; Y15-I173 HydrophobicContact CE2-CD1 3.58Å; Y15-M347 HydrophobicContact CD1-SD 4.01Å; Y15-M347 HydrophobicContact CE1-SD 3.92Å
16	V	82.6	Confident	77.8	Confident	85 Å²	85	53.4 Å²	53.4	52%	0.515	28%	0.28	S	S	.	.	H	α-helix	trans	-62.9	-40.7	173.6	169.4	0	0	0	0	110.7	V12 L13 F14 L19 F20	V12-V16 HydrophobicContact CG1-CG2 4.35Å; V12-V16 WeakPolarHBondContact O-CB 3.25Å; V12-V16 VanDerWaalsContact O-CG2 3.23Å; V12-V16 WeakPolarHBondContact O-CG2 3.37Å; V12-V16 PolarHBondContact O-N 3.5Å; L13-V16 PolarHBondContact O-N 3.18Å; F14-V16 PolarHBondContact O-N 3.43Å; V16-L19 PolarHBondContact O-N 3.26Å; V16-F20 VanDerWaalsContact O-CB 3.25Å; V16-F20 WeakPolarHBondContact O-CB 3.38Å; V16-F20 PolarHBondContact O-N 2.84Å
17	L	82.6	Confident	78	Confident	84 Å²	84	55.7 Å²	55.7	44%	0.44	28%	0.283	S	S	.	.	H	α-helix	trans	-63.1	-45.7	176.4	-178.3	145.7	0	0	0	111.7	L13 F14 Y15 F20 V21 V192	L13-L17 WeakPolarHBondContact O-CB 3.3Å; L13-L17 PolarHBondContact O-N 3.2Å; F14-L17 WeakPolarHBondContact O-CB 3.24Å; F14-L17 PolarHBondContact O-N 3.37Å; F14-L17 VanDerWaalsContact O-N 3.15Å; Y15-L17 VanDerWaalsContact C-N 3.31Å; Y15-L17 PolarHBondContact O-N 2.67Å; L17-F20 PolarHBondContact O-N 2.94Å; L17-V21 HydrophobicContact CD2-CG2 4.44Å; L17-V21 VanDerWaalsContact O-CG2 3.31Å; L17-V21 WeakPolarHBondContact O-CG2 3.26Å; L17-V21 PolarHBondContact O-N 3.14Å; L17-V192 HydrophobicContact CD2-CG1 3.77Å
18	I	79.8	Confident	78.2	Confident	0 Å²	0	59.9 Å²	59.9	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-63.2	-45.7	176.6	-63.5	-52.7	0	0	0	111.3	F14 Y15 F20 V21 G22 T189 V192 Q193 M347	F14-I18 HydrophobicContact CD1-CG1 4.38Å; F14-I18 HydrophobicContact CE1-CD1 4.42Å; F14-I18 HydrophobicContact CE1-CG1 3.78Å; F14-I18 HydrophobicContact CE2-CD1 4.09Å; F14-I18 HydrophobicContact CE2-CG1 4.15Å; F14-I18 HydrophobicContact CZ-CD1 3.74Å; F14-I18 HydrophobicContact CZ-CG1 3.6Å; F14-I18 WeakPolarHBondContact O-CG1 3.41Å; F14-I18 PolarHBondContact O-N 3.03Å; Y15-I18 PolarHBondContact O-N 3.32Å; I18-F20 VanDerWaalsContact C-N 3.31Å; I18-F20 PolarHBondContact O-N 3.39Å; I18-V21 PolarHBondContact O-N 3.18Å; I18-G22 PolarHBondContact O-N 2.87Å; I18-T189 HydrophobicContact CG2-CG2 3.89Å; I18-V192 HydrophobicContact CD1-CG1 4.14Å; I18-Q193 HydrophobicContact CD1-CG 3.54Å; I18-Q193 HydrophobicContact CG1-CG 4.28Å; I18-M347 HydrophobicContact CB-CE 4.3Å; I18-M347 HydrophobicContact CG2-CE 3.69Å; I18-M347 HydrophobicContact CG2-SD 4.42Å
19	L	79.3	Confident	77.8	Confident	64 Å²	64	58.7 Å²	58.7	34%	0.335	30%	0.295	S	S	.	.	H	α-helix	trans	-61.5	-40.7	177.3	-176.8	145.6	0	0	0	111.4	Y15 V16 G22 I23 F176	Y15-L19 VanDerWaalsContact O-CB 3.27Å; Y15-L19 WeakPolarHBondContact O-CB 3.39Å; Y15-L19 PolarHBondContact O-N 3.14Å; V16-L19 PolarHBondContact O-N 3.26Å; L19-G22 PolarHBondContact O-N 3.47Å; L19-I23 HydrophobicContact CD2-CD1 3.42Å; L19-I23 VanDerWaalsContact CD2-CD1 3.42Å; L19-I23 HydrophobicContact CD2-CG1 4.34Å; L19-I23 HydrophobicContact CG-CD1 4.11Å; L19-I23 WeakPolarHBondContact O-CB 3.34Å; L19-I23 VanDerWaalsContact O-CG1 3.29Å; L19-I23 WeakPolarHBondContact O-CG1 3.11Å; L19-I23 PolarHBondContact O-N 3.17Å; L19-F176 HydrophobicContact CD1-CD1 4.35Å; L19-F176 HydrophobicContact CD1-CE1 4.46Å
20	F	84	Confident	77	Confident	134 Å²	134	63.4 Å²	63.4	59%	0.588	31%	0.31	S	S	*	.	H	α-helix	trans	-62.1	-48.1	175.1	176.6	-96.1	0	0	0	111.8	V16 L17 I18 G22 I23 W24	V16-F20 VanDerWaalsContact O-CB 3.25Å; V16-F20 WeakPolarHBondContact O-CB 3.38Å; V16-F20 PolarHBondContact O-N 2.84Å; L17-F20 PolarHBondContact O-N 2.94Å; I18-F20 VanDerWaalsContact C-N 3.31Å; I18-F20 PolarHBondContact O-N 3.39Å; F20-G22 VanDerWaalsContact C-N 3.32Å; F20-G22 PolarHBondContact O-N 3.37Å; F20-I23 PolarHBondContact O-N 3.34Å; F20-W24 WeakPolarHBondContact O-CB 3.5Å; F20-W24 PolarHBondContact O-N 3.36Å
21	V	82.8	Confident	76.3	Confident	22 Å²	22	68.3 Å²	68.3	13%	0.133	33%	0.33	C	S	.	.	H	α-helix	trans	-60.4	-43.4	177.4	171.2	0	0	0	0	110.8	L17 I18 W24 A25 T189 V192	L17-V21 HydrophobicContact CD2-CG2 4.44Å; L17-V21 VanDerWaalsContact O-CG2 3.31Å; L17-V21 WeakPolarHBondContact O-CG2 3.26Å; L17-V21 PolarHBondContact O-N 3.14Å; I18-V21 PolarHBondContact O-N 3.18Å; V21-W24 PolarHBondContact O-N 3.24Å; V21-A25 VanDerWaalsContact O-CB 3.28Å; V21-A25 WeakPolarHBondContact O-CB 3.32Å; V21-A25 PolarHBondContact O-N 3.45Å; V21-T189 HydrophobicContact CB-CG2 4.39Å; V21-T189 HydrophobicContact CG1-CG2 4.15Å; V21-V192 HydrophobicContact CG1-CG2 4.13Å; V21-V192 HydrophobicContact CG2-CG2 4.33Å
22	G	77.5	Confident	75.3	Confident	3 Å²	3	71.4 Å²	71.4	3%	0.031	35%	0.353	C	S	.	.	H	α-helix	trans	-63.1	-47.8	178.2	0	0	0	0	0	112.8	I18 L19 F20 W24 A25 A26 S185	I18-G22 PolarHBondContact O-N 2.87Å; L19-G22 PolarHBondContact O-N 3.47Å; F20-G22 VanDerWaalsContact C-N 3.32Å; F20-G22 PolarHBondContact O-N 3.37Å; G22-W24 PolarHBondContact O-N 3.12Å; G22-A25 PolarHBondContact O-N 2.91Å; G22-A26 WeakPolarHBondContact O-CB 3.4Å; G22-A26 PolarHBondContact O-N 2.95Å; G22-S185 WeakPolarHBondContact CA-OG 3.25Å; G22-S185 PolarHBondContact O-OG 2.91Å
23	I	80.8	Confident	73.8	Confident	47 Å²	47	70.1 Å²	70.1	24%	0.241	36%	0.355	C	S	.	.	H	α-helix	trans	-62.4	-44.5	176.1	-69	175.9	0	0	0	110.9	L19 F20 A25 A26 W27 V180	L19-I23 HydrophobicContact CD2-CD1 3.42Å; L19-I23 VanDerWaalsContact CD2-CD1 3.42Å; L19-I23 HydrophobicContact CD2-CG1 4.34Å; L19-I23 HydrophobicContact CG-CD1 4.11Å; L19-I23 WeakPolarHBondContact O-CB 3.34Å; L19-I23 VanDerWaalsContact O-CG1 3.29Å; L19-I23 WeakPolarHBondContact O-CG1 3.11Å; L19-I23 PolarHBondContact O-N 3.17Å; F20-I23 PolarHBondContact O-N 3.34Å; I23-A25 PolarHBondContact O-N 3.03Å; I23-A26 PolarHBondContact O-N 3.25Å; I23-W27 HydrophobicContact CG2-CD2 3.81Å; I23-W27 VanDerWaalsContact CG2-CE2 3.47Å; I23-W27 HydrophobicContact CG2-CE3 4.13Å; I23-W27 HydrophobicContact CG2-CG 4.43Å; I23-W27 HydrophobicContact CG2-CH2 3.89Å; I23-W27 HydrophobicContact CG2-CZ2 3.53Å; I23-W27 HydrophobicContact CG2-CZ3 4.17Å; I23-W27 PolarHBondContact O-N 3.21Å; I23-V180 HydrophobicContact CG1-CG1 4.41Å
24	W	84	Confident	72.3	Confident	114 Å²	114	68.4 Å²	68.4	43%	0.432	35%	0.349	S	S	.	.	H	α-helix	trans	-60.8	-44.8	177.7	172.1	83	0	0	0	111.9	F20 V21 G22 A26 W27 K28 Y188	F20-W24 WeakPolarHBondContact O-CB 3.5Å; F20-W24 PolarHBondContact O-N 3.36Å; V21-W24 PolarHBondContact O-N 3.24Å; G22-W24 PolarHBondContact O-N 3.12Å; W24-A26 PolarHBondContact O-N 3.07Å; W24-W27 PolarHBondContact O-N 2.79Å; W24-K28 HydrophobicContact CH2-CD 4.05Å; W24-K28 HydrophobicContact CZ2-CD 4.12Å; W24-K28 WeakPolarHBondContact O-CB 3.44Å; W24-K28 PolarHBondContact O-N 3.01Å; W24-Y188 HydrophobicContact CZ3-CD1 4.23Å; W24-Y188 HydrophobicContact CZ3-CE1 4.38Å
25	A	77.2	Confident	70.7	Confident	2 Å²	2	70.5 Å²	70.5	2%	0.017	38%	0.379	C	S	.	.	H	α-helix	trans	-63.6	-41.3	177	0	0	0	0	0	111.7	V21 G22 I23 K28 N29 Y188	V21-A25 VanDerWaalsContact O-CB 3.28Å; V21-A25 WeakPolarHBondContact O-CB 3.32Å; V21-A25 PolarHBondContact O-N 3.45Å; G22-A25 PolarHBondContact O-N 2.91Å; I23-A25 PolarHBondContact O-N 3.03Å; A25-K28 PolarHBondContact O-N 2.94Å; A25-N29 PolarHBondContact O-N 3.46Å; A25-Y188 HydrophobicContact CB-CD2 3.94Å; A25-Y188 HydrophobicContact CB-CG 4.01Å
26	A	71.9	Confident	68.9	Low	17 Å²	17	78.7 Å²	78.7	14%	0.14	42%	0.418	C	S	.	.	H	α-helix	trans	-62.5	-41.5	175.1	0	0	0	0	0	112.2	G22 I23 W24 K30	G22-A26 WeakPolarHBondContact O-CB 3.4Å; G22-A26 PolarHBondContact O-N 2.95Å; I23-A26 PolarHBondContact O-N 3.25Å; W24-A26 PolarHBondContact O-N 3.07Å; A26-K30 PolarHBondContact O-N 2.86Å; A26-K30 VanDerWaalsContact O-N 3.12Å
27	W	75.2	Confident	67	Low	166 Å²	166	77.8 Å²	77.8	63%	0.629	43%	0.426	S	S	*	.	H	α-helix	trans	-68.7	-41.6	176.2	-72.3	-8.2	0	0	0	112.9	I23 W24 N29 K30 N31	I23-W27 HydrophobicContact CG2-CD2 3.81Å; I23-W27 VanDerWaalsContact CG2-CE2 3.47Å; I23-W27 HydrophobicContact CG2-CE3 4.13Å; I23-W27 HydrophobicContact CG2-CG 4.43Å; I23-W27 HydrophobicContact CG2-CH2 3.89Å; I23-W27 HydrophobicContact CG2-CZ2 3.53Å; I23-W27 HydrophobicContact CG2-CZ3 4.17Å; I23-W27 PolarHBondContact O-N 3.21Å; W24-W27 PolarHBondContact O-N 2.79Å; W27-N29 VanDerWaalsContact C-N 3.32Å; W27-N29 PolarHBondContact O-N 3.26Å; W27-K30 PolarHBondContact O-N 2.91Å; W27-N31 PolarHBondContact O-N 2.99Å
28	K	73.1	Confident	65.5	Low	89 Å²	89	76 Å²	76	39%	0.387	43%	0.427	S	S	.	.	H	α-helix	trans	-56.7	-48.7	175.3	-174.9	-178.5	177.2	-172.7	0	110.4	W24 A25 K30 N31 S32	W24-K28 HydrophobicContact CH2-CD 4.05Å; W24-K28 HydrophobicContact CZ2-CD 4.12Å; W24-K28 WeakPolarHBondContact O-CB 3.44Å; W24-K28 PolarHBondContact O-N 3.01Å; A25-K28 PolarHBondContact O-N 2.94Å; K28-K30 PolarHBondContact O-N 2.85Å; K28-N31 PolarHBondContact O-N 3.32Å; K28-S32 PolarHBondContact O-N 3.01Å; K28-S32 PolarHBondContact O-OG 3.48Å
29	N	65.4	Low	64.8	Low	41 Å²	41	80.2 Å²	80.2	22%	0.219	45%	0.45	C	S	.	.	H	α-helix	trans	-60.5	-42.9	177.9	-172.3	29.5	0	0	0	112.3	A25 W27 N31 S32	A25-N29 PolarHBondContact O-N 3.46Å; W27-N29 VanDerWaalsContact C-N 3.32Å; W27-N29 PolarHBondContact O-N 3.26Å; N29-N31 VanDerWaalsContact C-N 3.3Å; N29-N31 PolarHBondContact O-N 3.47Å; N29-S32 PolarHBondContact O-N 3.46Å
30	K	63.7	Low	64.4	Low	176 Å²	176	83.3 Å²	83.3	77%	0.765	46%	0.457	S	S	*	.	H	α-helix	trans	-63.1	-34.6	177.7	-170.5	-179.6	176.4	-169.4	0	112.9	A26 W27 K28	A26-K30 PolarHBondContact O-N 2.86Å; A26-K30 VanDerWaalsContact O-N 3.12Å; W27-K30 PolarHBondContact O-N 2.91Å; K28-K30 PolarHBondContact O-N 2.85Å
31	N	56.8	Low	63.8	Low	139 Å²	139	77 Å²	77	74%	0.743	43%	0.43	S	S	*	.	H	α-helix	trans	-87.4	-16.2	-178	-74.9	6.7	0	0	0	113.8	W27 K28 N29 G33	W27-N31 PolarHBondContact O-N 2.99Å; K28-N31 PolarHBondContact O-N 3.32Å; N29-N31 VanDerWaalsContact C-N 3.3Å; N29-N31 PolarHBondContact O-N 3.47Å; N31-G33 PolarHBondContact O-N 2.87Å
32	S	51.9	Low	63.4	Low	73 Å²	73	78.7 Å²	78.7	51%	0.51	44%	0.436	S	S	.	.	S	Bend	trans	-75.3	8.3	-179.4	-67.9	0	0	0	0	115.1	K28 N29 V34	K28-S32 PolarHBondContact O-N 3.01Å; K28-S32 PolarHBondContact O-OG 3.48Å; N29-S32 PolarHBondContact O-N 3.46Å; S32-V34 PolarHBondContact O-N 3.43Å
33	G	48.1	Very low	63	Low	49 Å²	49	79.8 Å²	79.8	51%	0.505	44%	0.444	S	S	.	.	S	Bend	trans	69.6	2.9	170.9	0	0	0	0	0	116.1	N31 G35 E36	N31-G33 PolarHBondContact O-N 2.87Å; G33-G35 PolarHBondContact O-N 3.44Å; G33-E36 PolarHBondContact O-N 2.84Å
34	V	48	Very low	62.6	Low	81 Å²	81	79.3 Å²	79.3	49%	0.491	44%	0.441	S	S	.	.	G	3₁₀ helix	trans	-64.6	-6.6	179.1	-174.8	0	0	0	0	112.6	S32	S32-V34 PolarHBondContact O-N 3.43Å
35	G	44.2	Very low	62.2	Low	72 Å²	72	74 Å²	74	74%	0.742	42%	0.421	S	S	*	.	G	3₁₀ helix	trans	-85	-1.3	179.1	0	0	0	0	0	116.9	G33	G33-G35 PolarHBondContact O-N 3.44Å
36	E	38.8	Very low	62	Low	195 Å²	195	73.9 Å²	73.9	91%	0.911	42%	0.42	S	S	*	.	G	3₁₀ helix	trans	-91.4	0.8	-177	-71	-168.5	159.4	0	0	114.7	G33	G33-E36 PolarHBondContact O-N 2.84Å
37	G	42.2	Very low	62	Low	66 Å²	66	73.1 Å²	73.1	68%	0.68	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-159.7	3.7	178.9	0	0	0	0	0	119.2
38	G	51	Low	61.7	Low	46 Å²	46	67 Å²	67	47%	0.474	40%	0.402	S	S	.	.	S	Bend	trans	-120.7	149.2	175.5	0	0	0	0	0	112.2	R40	G38-R40 PolarHBondContact O-N 3.49Å
39	D	65.1	Low	62	Low	89 Å²	89	64.4 Å²	64.4	48%	0.476	39%	0.39	S	S	.	.			trans	-56.2	121.3	-179.7	-75.3	-10	0	0	0	110.1	S41 E42 S43 D376	D39-S41 PolarHBondContact O-N 2.91Å; D39-E42 HydrophobicContact CB-CB 4.15Å; D39-E42 WeakPolarHBondContact O-CB 3.18Å; D39-E42 PolarHBondContact O-N 3.15Å; D39-S43 PolarHBondContact O-N 3.41Å; D39-S43 VanDerWaalsContact O-N 3.16Å; D39-D376 VanDerWaalsContact CA-OD2 3.24Å; D39-D376 WeakPolarHBondContact CA-OD2 3.31Å
40	R	70	Confident	62.6	Low	128 Å²	128	66.6 Å²	66.6	48%	0.483	40%	0.402	S	S	.	.	H	α-helix	trans	-61.9	-30.5	-176	178.2	-179.4	-179.7	-179.3	1.9	111.2	G38 S43 I44 D376 V380	G38-R40 PolarHBondContact O-N 3.49Å; R40-S43 PolarHBondContact O-OG 2.86Å; R40-I44 HydrophobicContact CG-CD1 4.36Å; R40-I44 PolarHBondContact O-N 2.91Å; R40-D376 HydrophobicContact CB-CB 4.07Å; R40-D376 PolarHBondContact N-OD2 2.98Å; R40-V380 HydrophobicContact CG-CG2 4.43Å
41	S	72.3	Confident	63.3	Low	3 Å²	3	58.5 Å²	58.5	2%	0.021	37%	0.367	C	S	.	.	H	α-helix	trans	-65.7	-42.1	174.2	58.5	0	0	0	0	112.2	D39 I44 M45 D376	D39-S41 PolarHBondContact O-N 2.91Å; S41-I44 PolarHBondContact O-N 3.29Å; S41-M45 WeakPolarHBondContact O-CG 3.4Å; S41-M45 PolarHBondContact O-N 2.98Å; S41-D376 WeakPolarHBondContact CB-OD1 3.36Å; S41-D376 PolarHBondContact OG-OD1 3.29Å
42	E	73.4	Confident	64.3	Low	57 Å²	57	53.9 Å²	53.9	27%	0.266	35%	0.352	S	S	.	.	H	α-helix	trans	-65	-41	177.8	-169.7	176.4	-165.5	0	0	111.4	D39 I44 M45 V46 R49	D39-E42 HydrophobicContact CB-CB 4.15Å; D39-E42 WeakPolarHBondContact O-CB 3.18Å; D39-E42 PolarHBondContact O-N 3.15Å; E42-I44 VanDerWaalsContact C-N 3.25Å; E42-I44 PolarHBondContact O-N 2.97Å; E42-M45 PolarHBondContact O-N 3.09Å; E42-V46 HydrophobicContact CG-CG2 3.37Å; E42-V46 WeakPolarHBondContact O-CG2 3.13Å; E42-V46 PolarHBondContact O-N 3.02Å; E42-R49 IonicContact OE1-CZ 3.94Å; E42-R49 VanDerWaalsContact OE1-CZ 3.28Å; E42-R49 IonicContact OE1-NE 3.28Å; E42-R49 PolarHBondContact OE1-NE 3.04Å; E42-R49 IonicContact OE1-NH2 3.88Å; E42-R49 PolarHBondContact OE1-NH2 3.21Å
43	S	70.9	Confident	65.8	Low	26 Å²	26	53.9 Å²	53.9	18%	0.182	35%	0.346	C	S	.	.	H	α-helix	trans	-61.2	-32.3	176.3	69	0	0	0	0	113.6	D39 R40 G47	D39-S43 PolarHBondContact O-N 3.41Å; D39-S43 VanDerWaalsContact O-N 3.16Å; R40-S43 PolarHBondContact O-OG 2.86Å; S43-G47 WeakPolarHBondContact O-CA 3.26Å; S43-G47 PolarHBondContact O-N 3.5Å; S43-G47 VanDerWaalsContact O-N 3.11Å
44	I	71.9	Confident	67.5	Low	37 Å²	37	57.3 Å²	57.3	19%	0.19	35%	0.348	C	S	.	.	H	α-helix	trans	-80.2	-37.3	177.6	-71.2	164.2	0	0	0	111.4	R40 S41 E42 L183 V380 M383	R40-I44 HydrophobicContact CG-CD1 4.36Å; R40-I44 PolarHBondContact O-N 2.91Å; S41-I44 PolarHBondContact O-N 3.29Å; E42-I44 VanDerWaalsContact C-N 3.25Å; E42-I44 PolarHBondContact O-N 2.97Å; I44-L183 WeakPolarHBondContact O-CB 3.44Å; I44-L183 PolarHBondContact O-N 2.76Å; I44-V380 HydrophobicContact CD1-CB 4.27Å; I44-V380 HydrophobicContact CD1-CG1 3.78Å; I44-V380 HydrophobicContact CD1-CG2 3.42Å; I44-V380 VanDerWaalsContact CD1-CG2 3.42Å; I44-M383 HydrophobicContact CB-CE 3.97Å; I44-M383 HydrophobicContact CG2-CE 3.47Å; I44-M383 VanDerWaalsContact CG2-CE 3.47Å; I44-M383 HydrophobicContact CG2-SD 4.23Å
45	M	74.9	Confident	69.3	Low	2 Å²	2	54.7 Å²	54.7	1%	0.01	33%	0.331	C	S	.	.	H	α-helix	trans	-79.5	-42.1	-176.9	-70.7	178.9	-175.7	0	0	113.6	S41 E42 V114 Q261 A362 R363 I379 M383	S41-M45 WeakPolarHBondContact O-CG 3.4Å; S41-M45 PolarHBondContact O-N 2.98Å; E42-M45 PolarHBondContact O-N 3.09Å; M45-V114 HydrophobicContact CB-CG1 4.08Å; M45-V114 HydrophobicContact SD-CG1 3.84Å; M45-Q261 VanDerWaalsContact O-CG 3.32Å; M45-Q261 WeakPolarHBondContact O-CG 3.48Å; M45-Q261 PolarHBondContact O-NE2 2.92Å; M45-A362 HydrophobicContact CE-CB 3.93Å; M45-R363 HydrophobicContact CE-CB 4.05Å; M45-R363 HydrophobicContact SD-CB 4.08Å; M45-I379 HydrophobicContact CE-CG2 3.59Å; M45-M383 HydrophobicContact CE-CE 4.09Å; M45-M383 HydrophobicContact CE-CG 4.05Å; M45-M383 HydrophobicContact CE-SD 3.33Å; M45-M383 WeakPolarHBondContact CE-SD 3.31Å; M45-M383 HydrophobicContact CG-CE 4.29Å; M45-M383 HydrophobicContact CG-SD 3.58Å; M45-M383 VanDerWaalsContact CG-SD 3.58Å; M45-M383 HydrophobicContact SD-SD 4.32Å
46	V	73.6	Confident	71.3	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-126.1	15.2	-175.1	-62.7	0	0	0	0	113.2	E42 G48 R49 V114 L264 S265	E42-V46 HydrophobicContact CG-CG2 3.37Å; E42-V46 WeakPolarHBondContact O-CG2 3.13Å; E42-V46 PolarHBondContact O-N 3.02Å; V46-G48 VanDerWaalsContact C-N 3.26Å; V46-G48 PolarHBondContact O-N 2.68Å; V46-R49 HydrophobicContact CG2-CG 3.94Å; V46-R49 PolarHBondContact O-N 2.93Å; V46-R49 VanDerWaalsContact O-N 3.14Å; V46-V114 HydrophobicContact CG1-CG1 4.08Å; V46-L264 HydrophobicContact CG1-CB 4.16Å; V46-S265 VanDerWaalsContact O-CA 3.27Å; V46-S265 WeakPolarHBondContact O-CA 3.07Å; V46-S265 WeakPolarHBondContact O-CB 3.34Å
47	G	70.9	Confident	73.6	Confident	0 Å²	0	42 Å²	42	0%	0	25%	0.254	C	S	.	.	G	3₁₀ helix	trans	61.6	33.5	172.6	0	0	0	0	0	113.2	S43 R49 D50 Y184	S43-G47 WeakPolarHBondContact O-CA 3.26Å; S43-G47 PolarHBondContact O-N 3.5Å; S43-G47 VanDerWaalsContact O-N 3.11Å; G47-R49 PolarHBondContact O-N 3.11Å; G47-D50 PolarHBondContact O-N 3.17Å; G47-Y184 VanDerWaalsContact CA-CE2 3.48Å; G47-Y184 WeakPolarHBondContact O-CE2 3.43Å; G47-Y184 VanDerWaalsContact O-CZ 3.22Å; G47-Y184 PolarHBondContact O-OH 3.29Å
48	G	70.4	Confident	75.9	Confident	38 Å²	38	41.3 Å²	41.3	39%	0.392	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	63	8.1	-180	0	0	0	0	0	114.8	V46 D50	V46-G48 VanDerWaalsContact C-N 3.26Å; V46-G48 PolarHBondContact O-N 2.68Å; G48-D50 PolarHBondContact O-N 3.22Å
49	R	79.5	Confident	77.6	Confident	34 Å²	34	39.1 Å²	39.1	13%	0.128	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	58.5	30	-175.9	-47.5	-177.2	-171.4	-121	7	114.6	E42 V46 G47 G112 Y113 S265 S267	E42-R49 IonicContact OE1-CZ 3.94Å; E42-R49 VanDerWaalsContact OE1-CZ 3.28Å; E42-R49 IonicContact OE1-NE 3.28Å; E42-R49 PolarHBondContact OE1-NE 3.04Å; E42-R49 IonicContact OE1-NH2 3.88Å; E42-R49 PolarHBondContact OE1-NH2 3.21Å; V46-R49 HydrophobicContact CG2-CG 3.94Å; V46-R49 PolarHBondContact O-N 2.93Å; V46-R49 VanDerWaalsContact O-N 3.14Å; G47-R49 PolarHBondContact O-N 3.11Å; R49-G112 PolarHBondContact NH2-O 2.9Å; R49-Y113 PolarHBondContact NH1-O 2.82Å; R49-Y113 VanDerWaalsContact NH1-O 3.16Å; R49-Y113 PolarHBondContact NH2-O 3.13Å; R49-S265 CarbonylContact C-O 3.44Å; R49-S265 VanDerWaalsContact C-O 3.27Å; R49-S265 WeakPolarHBondContact CA-O 3.12Å; R49-S267 WeakPolarHBondContact O-CA 3.48Å; R49-S267 PolarHBondContact O-N 3.26Å
50	D	77.8	Confident	78.8	Confident	87 Å²	87	35 Å²	35	47%	0.465	19%	0.187	S	C	.	.			trans	-118.3	24.4	-179.1	-168.5	41.4	0	0	0	112.1	G47 G48 G52	G47-D50 PolarHBondContact O-N 3.17Å; G48-D50 PolarHBondContact O-N 3.22Å; D50-G52 PolarHBondContact O-N 2.94Å
51	I	78.1	Confident	79.8	Confident	6 Å²	6	29.1 Å²	29.1	3%	0.031	17%	0.166	C	C	.	.	B	Isolated β-bridge	trans	-74.1	112.8	176	-60.8	-168.6	0	0	0	108.9	V55 G56 L183 Y184 A187 S265	I51-V55 HydrophobicContact CG2-CB 4.1Å; I51-V55 HydrophobicContact CG2-CG1 4.07Å; I51-G56 VanDerWaalsContact CG2-CA 3.49Å; I51-L183 HydrophobicContact CD1-CD2 4.2Å; I51-L183 HydrophobicContact CD1-CG 4.46Å; I51-Y184 HydrophobicContact CG1-CE1 4.32Å; I51-A187 HydrophobicContact CD1-CB 4.23Å; I51-S265 PolarHBondContact N-O 3.04Å
52	G	77.9	Confident	80.6	Confident	43 Å²	43	29 Å²	29	44%	0.443	17%	0.165	S	C	.	.			trans	-66.7	163.8	176.5	0	0	0	0	0	113.3	D50 F54 V55 G56	D50-G52 PolarHBondContact O-N 2.94Å; G52-F54 VanDerWaalsContact C-N 3.29Å; G52-F54 PolarHBondContact O-N 3Å; G52-V55 PolarHBondContact O-N 3.01Å; G52-G56 PolarHBondContact O-N 2.96Å
53	L	83.1	Confident	81.1	Confident	72 Å²	72	26.4 Å²	26.4	38%	0.377	15%	0.153	S	C	.	.	H	α-helix	trans	-56.6	-39.5	-173	-172.2	73.2	0	0	0	113.5	G57 Y271 V274 L275	L53-G57 PolarHBondContact O-N 3.38Å; L53-Y271 HydrophobicContact CB-CD1 4.42Å; L53-Y271 HydrophobicContact CB-CE1 4.48Å; L53-Y271 HydrophobicContact CD1-CD1 4.07Å; L53-V274 HydrophobicContact CD1-CB 4.2Å; L53-V274 HydrophobicContact CD1-CG1 3.66Å; L53-L275 HydrophobicContact CD1-CD2 3.76Å; L53-L275 HydrophobicContact CD1-CG 4.31Å; L53-L275 HydrophobicContact CG-CD2 4.49Å; L53-L275 WeakPolarHBondContact O-CD2 3.29Å
54	F	84.5	Confident	81.7	Confident	122 Å²	122	25.6 Å²	25.6	54%	0.535	15%	0.146	S	C	.	.	H	α-helix	trans	-65.2	-61.6	179.9	-175.8	-96	0	0	0	111.2	G52 G56 G57 F58 V191 F195	G52-F54 VanDerWaalsContact C-N 3.29Å; G52-F54 PolarHBondContact O-N 3Å; F54-G56 VanDerWaalsContact C-N 3.28Å; F54-G56 PolarHBondContact O-N 3.21Å; F54-G57 PolarHBondContact O-N 3.41Å; F54-F58 HydrophobicContact CD1-CD2 4.5Å; F54-F58 HydrophobicContact CD2-CD2 4.17Å; F54-F58 AromaticContact CD2-CE2 3.75Å; F54-F58 HydrophobicContact CD2-CE2 3.75Å; F54-F58 HydrophobicContact CE1-CD2 4.36Å; F54-F58 HydrophobicContact CE1-CE2 4.35Å; F54-F58 HydrophobicContact CE2-CD2 4.03Å; F54-F58 AromaticContact CE2-CE2 3.33Å; F54-F58 HydrophobicContact CE2-CE2 3.33Å; F54-F58 AromaticContact CE2-CZ 3.93Å; F54-F58 HydrophobicContact CE2-CZ 3.93Å; F54-F58 HydrophobicContact CG-CD2 4.41Å; F54-F58 HydrophobicContact CG-CE2 4.42Å; F54-F58 HydrophobicContact CZ-CD2 4.13Å; F54-F58 AromaticContact CZ-CE2 3.67Å; F54-F58 HydrophobicContact CZ-CE2 3.67Å; F54-F58 HydrophobicContact CZ-CZ 4.05Å; F54-F58 VanDerWaalsContact O-CD2 3.27Å; F54-F58 WeakPolarHBondContact O-CD2 3.32Å; F54-F58 PolarHBondContact O-N 3Å; F54-V191 HydrophobicContact CE1-CG1 4.09Å; F54-F195 HydrophobicContact CZ-CE2 4.05Å; F54-F195 HydrophobicContact CZ-CZ 4.09Å
55	V	85.6	Confident	82.3	Confident	25 Å²	25	23.8 Å²	23.8	15%	0.152	14%	0.137	C	C	.	.	H	α-helix	trans	-58.7	-43.3	-179.7	178.4	0	0	0	0	110.6	I51 G52 G57 F58 T59 A187 Y188 V191	I51-V55 HydrophobicContact CG2-CB 4.1Å; I51-V55 HydrophobicContact CG2-CG1 4.07Å; G52-V55 PolarHBondContact O-N 3.01Å; V55-G57 PolarHBondContact O-N 2.78Å; V55-F58 PolarHBondContact O-N 3.28Å; V55-T59 WeakPolarHBondContact O-CG2 3.21Å; V55-T59 PolarHBondContact O-N 2.84Å; V55-A187 HydrophobicContact CG1-CB 3.89Å; V55-Y188 HydrophobicContact CG2-CE1 4.4Å; V55-V191 HydrophobicContact CG1-CG2 4.2Å
56	G	85.9	Confident	82.5	Confident	1 Å²	1	23.8 Å²	23.8	1%	0.01	14%	0.137	C	C	.	.	H	α-helix	trans	-60.5	-40.3	178.6	0	0	0	0	0	113.8	I51 G52 F54 T59 M60	I51-G56 VanDerWaalsContact CG2-CA 3.49Å; G52-G56 PolarHBondContact O-N 2.96Å; F54-G56 VanDerWaalsContact C-N 3.28Å; F54-G56 PolarHBondContact O-N 3.21Å; G56-T59 WeakPolarHBondContact O-CG2 3.14Å; G56-M60 WeakPolarHBondContact O-CB 3.42Å; G56-M60 PolarHBondContact O-N 3.29Å
57	G	87.2	Confident	82.4	Confident	1 Å²	1	23.9 Å²	23.9	1%	0.01	14%	0.138	C	C	.	.	H	α-helix	trans	-71	-43.3	-177.7	0	0	0	0	0	111.5	L53 F54 V55 T61	L53-G57 PolarHBondContact O-N 3.38Å; F54-G57 PolarHBondContact O-N 3.41Å; V55-G57 PolarHBondContact O-N 2.78Å; G57-T61 WeakPolarHBondContact O-CB 3.49Å; G57-T61 PolarHBondContact O-N 2.89Å; G57-T61 PolarHBondContact O-OG1 3.49Å
58	F	89.2	Confident	82.7	Confident	50 Å²	50	24.1 Å²	24.1	22%	0.219	14%	0.14	C	C	.	.	H	α-helix	trans	-67.5	-47.9	177.4	-81.7	-100.7	0	0	0	111.6	F54 V55 M60 T61 A62 V191 L194 F195	F54-F58 HydrophobicContact CD1-CD2 4.5Å; F54-F58 HydrophobicContact CD2-CD2 4.17Å; F54-F58 AromaticContact CD2-CE2 3.75Å; F54-F58 HydrophobicContact CD2-CE2 3.75Å; F54-F58 HydrophobicContact CE1-CD2 4.36Å; F54-F58 HydrophobicContact CE1-CE2 4.35Å; F54-F58 HydrophobicContact CE2-CD2 4.03Å; F54-F58 AromaticContact CE2-CE2 3.33Å; F54-F58 HydrophobicContact CE2-CE2 3.33Å; F54-F58 AromaticContact CE2-CZ 3.93Å; F54-F58 HydrophobicContact CE2-CZ 3.93Å; F54-F58 HydrophobicContact CG-CD2 4.41Å; F54-F58 HydrophobicContact CG-CE2 4.42Å; F54-F58 HydrophobicContact CZ-CD2 4.13Å; F54-F58 AromaticContact CZ-CE2 3.67Å; F54-F58 HydrophobicContact CZ-CE2 3.67Å; F54-F58 HydrophobicContact CZ-CZ 4.05Å; F54-F58 VanDerWaalsContact O-CD2 3.27Å; F54-F58 WeakPolarHBondContact O-CD2 3.32Å; F54-F58 PolarHBondContact O-N 3Å; V55-F58 PolarHBondContact O-N 3.28Å; F58-M60 PolarHBondContact O-N 3.16Å; F58-T61 PolarHBondContact O-N 3.46Å; F58-A62 VanDerWaalsContact O-CB 3.29Å; F58-A62 WeakPolarHBondContact O-CB 3.34Å; F58-A62 PolarHBondContact O-N 3.39Å; F58-V191 HydrophobicContact CB-CB 4.34Å; F58-V191 HydrophobicContact CB-CG2 3.7Å; F58-V191 HydrophobicContact CD1-CG1 4.46Å; F58-V191 HydrophobicContact CG-CG1 4.5Å; F58-V191 HydrophobicContact CG-CG2 4.46Å; F58-L194 HydrophobicContact CB-CD2 4.28Å; F58-L194 HydrophobicContact CD1-CB 4.28Å; F58-L194 HydrophobicContact CD1-CD2 3.6Å; F58-L194 HydrophobicContact CD1-CG 4.36Å; F58-L194 HydrophobicContact CE1-CD2 4.27Å; F58-L194 HydrophobicContact CG-CD2 4.23Å; F58-F195 HydrophobicContact CD1-CD2 4.34Å; F58-F195 AromaticContact CD1-CE2 3.93Å; F58-F195 HydrophobicContact CD1-CE2 3.93Å; F58-F195 HydrophobicContact CD1-CZ 4.34Å; F58-F195 HydrophobicContact CE1-CD2 4.03Å; F58-F195 AromaticContact CE1-CE1 3.98Å; F58-F195 HydrophobicContact CE1-CE1 3.98Å; F58-F195 AromaticContact CE1-CE2 3.42Å; F58-F195 HydrophobicContact CE1-CE2 3.42Å; F58-F195 VanDerWaalsContact CE1-CE2 3.42Å; F58-F195 AromaticContact CE1-CZ 3.4Å; F58-F195 HydrophobicContact CE1-CZ 3.4Å; F58-F195 HydrophobicContact CZ-CE1 4.23Å; F58-F195 AromaticContact CZ-CE2 3.87Å; F58-F195 HydrophobicContact CZ-CE2 3.87Å; F58-F195 AromaticContact CZ-CZ 3.5Å; F58-F195 HydrophobicContact CZ-CZ 3.5Å
59	T	88.3	Confident	83.3	Confident	1 Å²	1	22.5 Å²	22.5	1%	0.006	12%	0.122	C	C	.	.	H	α-helix	trans	-62.4	-41	176.6	179.7	0	0	0	0	112.3	V55 G56 T61 A62 T63 A187 D190 R262	V55-T59 WeakPolarHBondContact O-CG2 3.21Å; V55-T59 PolarHBondContact O-N 2.84Å; G56-T59 WeakPolarHBondContact O-CG2 3.14Å; T59-T61 VanDerWaalsContact C-N 3.31Å; T59-T61 PolarHBondContact O-N 2.74Å; T59-A62 PolarHBondContact O-N 2.88Å; T59-T63 WeakPolarHBondContact O-CB 3.22Å; T59-T63 PolarHBondContact O-N 3.48Å; T59-T63 PolarHBondContact O-OG1 3.33Å; T59-A187 HydrophobicContact CG2-CB 4.24Å; T59-D190 WeakPolarHBondContact CB-OD2 3.19Å; T59-D190 PolarHBondContact OG1-OD2 3.19Å; T59-R262 HydrophobicContact CG2-CG 3.88Å; T59-R262 PolarHBondContact OG1-NE 3.16Å
60	M	90	Very high	83.7	Confident	1 Å²	1	21 Å²	21	1%	0.005	12%	0.116	C	C	.	.	H	α-helix	trans	-66.1	-35.5	178.1	-170.3	176.8	-74.6	0	0	111.5	G56 F58 L97 Y259 R262 V263 L275 S276 A279	G56-M60 WeakPolarHBondContact O-CB 3.42Å; G56-M60 PolarHBondContact O-N 3.29Å; F58-M60 PolarHBondContact O-N 3.16Å; M60-L97 HydrophobicContact CG-CD2 4.41Å; M60-L97 HydrophobicContact SD-CD2 4.42Å; M60-Y259 HydrophobicContact CE-CD2 4.49Å; M60-Y259 HydrophobicContact CE-CE2 4.22Å; M60-Y259 HydrophobicContact SD-CD2 4.35Å; M60-Y259 HydrophobicContact SD-CE2 3.99Å; M60-R262 HydrophobicContact CB-CB 4.34Å; M60-R262 HydrophobicContact CB-CG 4.35Å; M60-R262 HydrophobicContact CE-CB 3.53Å; M60-R262 HydrophobicContact CG-CB 4.42Å; M60-V263 HydrophobicContact CE-CG2 3.81Å; M60-L275 HydrophobicContact CE-CB 3.83Å; M60-L275 HydrophobicContact SD-CB 3.99Å; M60-S276 WeakPolarHBondContact SD-CA 3.34Å; M60-S276 PolarHBondContact SD-N 3.41Å; M60-A279 HydrophobicContact CB-CB 3.87Å; M60-A279 HydrophobicContact CG-CB 3.55Å; M60-A279 HydrophobicContact SD-CB 3.9Å
61	T	91.3	Very high	84	Confident	6 Å²	6	17.3 Å²	17.3	4%	0.037	10%	0.097	C	C	.	.	H	α-helix	trans	-68.5	-51	172.9	-52.8	0	0	0	0	111.3	G57 F58 T59 T63 W64 V65 L194 A279 M286	G57-T61 WeakPolarHBondContact O-CB 3.49Å; G57-T61 PolarHBondContact O-N 2.89Å; G57-T61 PolarHBondContact O-OG1 3.49Å; F58-T61 PolarHBondContact O-N 3.46Å; T59-T61 VanDerWaalsContact C-N 3.31Å; T59-T61 PolarHBondContact O-N 2.74Å; T61-T63 PolarHBondContact O-N 2.54Å; T61-W64 PolarHBondContact O-N 3.01Å; T61-W64 VanDerWaalsContact O-N 3.08Å; T61-V65 HydrophobicContact CG2-CG2 3.85Å; T61-V65 WeakPolarHBondContact O-CB 3.34Å; T61-V65 WeakPolarHBondContact O-CG2 3.17Å; T61-V65 PolarHBondContact O-N 3.47Å; T61-L194 HydrophobicContact CG2-CD1 4.19Å; T61-L194 HydrophobicContact CG2-CD2 3.85Å; T61-A279 WeakPolarHBondContact OG1-CA 3.29Å; T61-M286 HydrophobicContact CG2-CG 4.44Å
62	A	87.8	Confident	84.2	Confident	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-59.3	-35	-177.4	0	0	0	0	0	112.9	F58 T59 W64 V65 D190 L194	F58-A62 VanDerWaalsContact O-CB 3.29Å; F58-A62 WeakPolarHBondContact O-CB 3.34Å; F58-A62 PolarHBondContact O-N 3.39Å; T59-A62 PolarHBondContact O-N 2.88Å; A62-W64 VanDerWaalsContact C-N 3.28Å; A62-W64 PolarHBondContact O-N 3.44Å; A62-V65 CarbonylContact O-C 3.53Å; A62-V65 PolarHBondContact O-N 3.31Å; A62-D190 HydrophobicContact CB-CB 3.78Å; A62-L194 HydrophobicContact CB-CB 4.2Å; A62-L194 HydrophobicContact CB-CD1 4.2Å
63	T	83.9	Confident	84.8	Confident	2 Å²	2	15.6 Å²	15.6	1%	0.012	8%	0.08	C	C	.	.	H	α-helix	trans	-54.2	-45.8	174.9	-67	0	0	0	0	111.9	T59 T61 W143 V258 R262 S349	T59-T63 WeakPolarHBondContact O-CB 3.22Å; T59-T63 PolarHBondContact O-N 3.48Å; T59-T63 PolarHBondContact O-OG1 3.33Å; T61-T63 PolarHBondContact O-N 2.54Å; T63-W143 HydrophobicContact CG2-CH2 4.31Å; T63-W143 WeakPolarHBondContact O-CH2 3.4Å; T63-V258 HydrophobicContact CG2-CB 4.01Å; T63-V258 HydrophobicContact CG2-CG1 3.27Å; T63-R262 VanDerWaalsContact OG1-CZ 3.23Å; T63-R262 PolarHBondContact OG1-NE 2.82Å; T63-R262 VanDerWaalsContact OG1-NE 3.12Å; T63-R262 PolarHBondContact OG1-NH2 2.89Å; T63-S349 PolarHBondContact O-OG 2.98Å
64	W	84.2	Confident	85.2	Confident	9 Å²	9	12.1 Å²	12.1	3%	0.034	6%	0.062	C	C	.	.	H	α-helix	trans	-86.2	-33.5	-177.7	-73.8	102.8	0	0	0	112.8	T61 A62 G66 Y69 Y93 L97 G253 W256	T61-W64 PolarHBondContact O-N 3.01Å; T61-W64 VanDerWaalsContact O-N 3.08Å; A62-W64 VanDerWaalsContact C-N 3.28Å; A62-W64 PolarHBondContact O-N 3.44Å; W64-G66 PolarHBondContact O-N 3.16Å; W64-Y69 VanDerWaalsContact O-CB 3.24Å; W64-Y69 WeakPolarHBondContact O-CB 3.46Å; W64-Y93 HydrophobicContact CD2-CD1 4.48Å; W64-Y93 AromaticContact CE3-CD1 3.5Å; W64-Y93 HydrophobicContact CE3-CD1 3.5Å; W64-Y93 VanDerWaalsContact CE3-CD1 3.5Å; W64-Y93 HydrophobicContact CE3-CD2 4.45Å; W64-Y93 AromaticContact CE3-CE1 3.92Å; W64-Y93 HydrophobicContact CE3-CE1 3.92Å; W64-Y93 AromaticContact CE3-CG 3.78Å; W64-Y93 HydrophobicContact CE3-CG 3.78Å; W64-Y93 AromaticContact CH2-CD1 3.83Å; W64-Y93 HydrophobicContact CH2-CD1 3.83Å; W64-Y93 HydrophobicContact CH2-CE1 4.01Å; W64-Y93 AromaticContact CZ3-CD1 3.13Å; W64-Y93 HydrophobicContact CZ3-CD1 3.13Å; W64-Y93 AromaticContact CZ3-CE1 3.23Å; W64-Y93 HydrophobicContact CZ3-CE1 3.23Å; W64-Y93 AromaticContact CZ3-CG 3.91Å; W64-Y93 HydrophobicContact CZ3-CG 3.91Å; W64-L97 HydrophobicContact CG-CD1 4.27Å; W64-L97 VanDerWaalsContact NE1-CD2 3.34Å; W64-G253 VanDerWaalsContact CH2-O 3.23Å; W64-G253 WeakPolarHBondContact CH2-O 3.28Å; W64-G253 VanDerWaalsContact CZ2-O 3.28Å; W64-G253 WeakPolarHBondContact CZ2-O 3.3Å; W64-W256 HydrophobicContact CH2-CD2 4.3Å; W64-W256 HydrophobicContact CH2-CE3 4.13Å; W64-W256 HydrophobicContact CH2-CG 4.42Å; W64-W256 HydrophobicContact CZ3-CE3 4.33Å; W64-W256 HydrophobicContact CZ3-CZ3 4.44Å
65	V	84.1	Confident	85.4	Confident	0 Å²	0	7.8 Å²	7.8	0%	0	4%	0.044	C	C	.	.	S	Bend	trans	-78	64.1	176.1	-178.1	0	0	0	0	109.3	T61 A62 Y69 I70 L194 C283 M286	T61-V65 HydrophobicContact CG2-CG2 3.85Å; T61-V65 WeakPolarHBondContact O-CB 3.34Å; T61-V65 WeakPolarHBondContact O-CG2 3.17Å; T61-V65 PolarHBondContact O-N 3.47Å; A62-V65 CarbonylContact O-C 3.53Å; A62-V65 PolarHBondContact O-N 3.31Å; V65-Y69 HydrophobicContact CG2-CE1 4.32Å; V65-I70 HydrophobicContact CG1-CD1 3.66Å; V65-I70 HydrophobicContact CG1-CG1 4Å; V65-L194 HydrophobicContact CB-CD1 4.31Å; V65-L194 HydrophobicContact CG1-CD1 4.3Å; V65-C283 HydrophobicContact CG2-CB 4.39Å; V65-M286 HydrophobicContact CB-CB 4.46Å; V65-M286 HydrophobicContact CG1-CB 3.73Å; V65-M286 HydrophobicContact CG1-CE 4.04Å; V65-M286 HydrophobicContact CG1-CG 4.17Å; V65-M286 HydrophobicContact CG2-CB 3.78Å; V65-M286 HydrophobicContact CG2-CG 4.09Å
66	G	78.8	Confident	85.5	Confident	2 Å²	2	7.9 Å²	7.9	2%	0.021	4%	0.041	C	C	.	.			trans	-95.5	179	178.7	0	0	0	0	0	114.1	W64 G68 Y69 I70 S349	W64-G66 PolarHBondContact O-N 3.16Å; G66-G68 PolarHBondContact O-N 3.27Å; G66-Y69 WeakPolarHBondContact O-CB 3.46Å; G66-Y69 PolarHBondContact O-N 3.07Å; G66-Y69 VanDerWaalsContact O-N 3.13Å; G66-I70 PolarHBondContact O-N 3Å; G66-S349 WeakPolarHBondContact CA-OG 3.4Å
67	G	72.8	Confident	85.8	Confident	1 Å²	1	7.9 Å²	7.9	1%	0.01	4%	0.041	C	C	.	.	H	α-helix	trans	-55.3	-46.4	175.9	0	0	0	0	0	113.6	Y69 I70 N71	G67-Y69 VanDerWaalsContact C-N 3.33Å; G67-Y69 PolarHBondContact O-N 3.4Å; G67-I70 PolarHBondContact O-N 3.37Å; G67-N71 WeakPolarHBondContact O-CB 3.04Å; G67-N71 PolarHBondContact O-N 3.43Å
68	G	75.6	Confident	86	Confident	5 Å²	5	7.8 Å²	7.8	5%	0.052	4%	0.041	C	C	.	.	H	α-helix	trans	-64.5	-35.3	176.8	0	0	0	0	0	113.4	G66 G72	G66-G68 PolarHBondContact O-N 3.27Å; G68-G72 VanDerWaalsContact O-CA 3.28Å; G68-G72 WeakPolarHBondContact O-CA 3.36Å; G68-G72 PolarHBondContact O-N 3.38Å
69	Y	84.8	Confident	86	Confident	5 Å²	5	7 Å²	7	2%	0.02	4%	0.039	C	C	.	.	H	α-helix	trans	-68.3	-49.3	177.6	-179.5	-89.6	0	0	0	111.5	W64 V65 G66 G67 T73 A89 P90 Y93 C283 A287	W64-Y69 VanDerWaalsContact O-CB 3.24Å; W64-Y69 WeakPolarHBondContact O-CB 3.46Å; V65-Y69 HydrophobicContact CG2-CE1 4.32Å; G66-Y69 WeakPolarHBondContact O-CB 3.46Å; G66-Y69 PolarHBondContact O-N 3.07Å; G66-Y69 VanDerWaalsContact O-N 3.13Å; G67-Y69 VanDerWaalsContact C-N 3.33Å; G67-Y69 PolarHBondContact O-N 3.4Å; Y69-T73 WeakPolarHBondContact O-CB 3.45Å; Y69-T73 PolarHBondContact O-N 2.91Å; Y69-T73 VanDerWaalsContact O-N 3.12Å; Y69-T73 PolarHBondContact O-OG1 3.04Å; Y69-A89 HydrophobicContact CD2-CB 4.43Å; Y69-P90 HydrophobicContact CE2-CB 4.43Å; Y69-P90 HydrophobicContact CE2-CG 4.46Å; Y69-P90 VanDerWaalsContact OH-CA 3.22Å; Y69-P90 WeakPolarHBondContact OH-CA 3.31Å; Y69-P90 WeakPolarHBondContact OH-CB 3.24Å; Y69-Y93 AromaticContact CD2-CD2 3.95Å; Y69-Y93 HydrophobicContact CD2-CD2 3.95Å; Y69-Y93 HydrophobicContact CE2-CD2 4.08Å; Y69-C283 PolarHBondContact OH-O 3.07Å; Y69-A287 HydrophobicContact CE1-CB 3.89Å
70	I	87.3	Confident	85.9	Confident	1 Å²	1	8.5 Å²	8.5	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-73.2	-51.8	-177.6	-66.2	170.5	0	0	0	110.8	V65 G66 G67 T73 A74 I197 L201 S290 L322 A345	V65-I70 HydrophobicContact CG1-CD1 3.66Å; V65-I70 HydrophobicContact CG1-CG1 4Å; G66-I70 PolarHBondContact O-N 3Å; G67-I70 PolarHBondContact O-N 3.37Å; I70-T73 PolarHBondContact O-N 3.46Å; I70-A74 PolarHBondContact O-N 3.28Å; I70-I197 HydrophobicContact CD1-CG2 3.68Å; I70-L201 HydrophobicContact CD1-CD1 4.09Å; I70-L201 HydrophobicContact CG2-CD1 3.84Å; I70-S290 WeakPolarHBondContact CG2-OG 3.45Å; I70-S290 WeakPolarHBondContact O-CB 3.47Å; I70-L322 HydrophobicContact CG2-CD1 3.24Å; I70-A345 HydrophobicContact CD1-CB 3.73Å
71	N	84.6	Confident	85.5	Confident	10 Å²	10	14.1 Å²	14.1	5%	0.053	8%	0.078	C	C	.	.	H	α-helix	trans	-68.1	-44	-178	-65.6	-8	0	0	0	111	G67 T73 A74 E75	G67-N71 WeakPolarHBondContact O-CB 3.04Å; G67-N71 PolarHBondContact O-N 3.43Å; N71-T73 VanDerWaalsContact C-N 3.33Å; N71-T73 PolarHBondContact O-N 3.18Å; N71-A74 PolarHBondContact O-N 3.18Å; N71-A74 VanDerWaalsContact O-N 3.16Å; N71-E75 WeakPolarHBondContact O-CB 3.34Å; N71-E75 PolarHBondContact O-N 3.4Å
72	G	81.9	Confident	85.3	Confident	11 Å²	11	17.1 Å²	17.1	11%	0.113	9%	0.089	C	C	.	.	H	α-helix	trans	-63.3	-37.7	177.8	0	0	0	0	0	112.5	G68 A74 E75 Y76	G68-G72 VanDerWaalsContact O-CA 3.28Å; G68-G72 WeakPolarHBondContact O-CA 3.36Å; G68-G72 PolarHBondContact O-N 3.38Å; G72-A74 VanDerWaalsContact C-N 3.35Å; G72-A74 PolarHBondContact O-N 3.15Å; G72-E75 PolarHBondContact O-N 3.19Å; G72-Y76 WeakPolarHBondContact O-CD2 3.48Å; G72-Y76 PolarHBondContact O-N 2.98Å
73	T	89.8	Confident	85.3	Confident	2 Å²	2	17.1 Å²	17.1	1%	0.012	9%	0.089	C	C	.	.	H	α-helix	trans	-62	-43.6	173.6	-63.5	0	0	0	0	111.3	Y69 I70 N71 V77 A87 P90 V291	Y69-T73 WeakPolarHBondContact O-CB 3.45Å; Y69-T73 PolarHBondContact O-N 2.91Å; Y69-T73 VanDerWaalsContact O-N 3.12Å; Y69-T73 PolarHBondContact O-OG1 3.04Å; I70-T73 PolarHBondContact O-N 3.46Å; N71-T73 VanDerWaalsContact C-N 3.33Å; N71-T73 PolarHBondContact O-N 3.18Å; T73-V77 VanDerWaalsContact O-CG2 3.24Å; T73-V77 WeakPolarHBondContact O-CG2 3.35Å; T73-V77 PolarHBondContact O-N 2.84Å; T73-A87 HydrophobicContact CG2-CB 4.45Å; T73-P90 HydrophobicContact CG2-CG 3.86Å; T73-P90 WeakPolarHBondContact OG1-CG 3.42Å; T73-V291 HydrophobicContact CG2-CG2 3.48Å; T73-V291 VanDerWaalsContact CG2-CG2 3.48Å
74	A	91.5	Very high	85.7	Confident	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-66.9	-40.8	177.8	0	0	0	0	0	112.4	I70 N71 G72 V77 Y78 S290 G294 I321 L322	I70-A74 PolarHBondContact O-N 3.28Å; N71-A74 PolarHBondContact O-N 3.18Å; N71-A74 VanDerWaalsContact O-N 3.16Å; G72-A74 VanDerWaalsContact C-N 3.35Å; G72-A74 PolarHBondContact O-N 3.15Å; A74-V77 PolarHBondContact O-N 3.12Å; A74-Y78 VanDerWaalsContact O-CB 3.28Å; A74-Y78 WeakPolarHBondContact O-CB 3.5Å; A74-Y78 PolarHBondContact O-N 3.33Å; A74-S290 WeakPolarHBondContact CB-O 3.47Å; A74-G294 WeakPolarHBondContact O-CA 3.41Å; A74-I321 HydrophobicContact CB-CG2 3.99Å; A74-L322 HydrophobicContact CB-CB 3.92Å; A74-L322 HydrophobicContact CB-CD1 4.01Å; A74-L322 HydrophobicContact CB-CG 4.44Å
75	E	88.1	Confident	86.1	Confident	31 Å²	31	20.2 Å²	20.2	15%	0.145	11%	0.11	C	C	.	.	H	α-helix	trans	-57.9	-51.7	175.8	176.7	-177.6	-171.4	0	0	111.5	N71 G72 V77 Y78 L79	N71-E75 WeakPolarHBondContact O-CB 3.34Å; N71-E75 PolarHBondContact O-N 3.4Å; G72-E75 PolarHBondContact O-N 3.19Å; E75-V77 VanDerWaalsContact C-N 3.32Å; E75-V77 PolarHBondContact O-N 3.32Å; E75-Y78 WeakPolarHBondContact O-CB 3.44Å; E75-Y78 PolarHBondContact O-N 2.72Å; E75-Y78 VanDerWaalsContact O-N 3.07Å; E75-L79 HydrophobicContact CG-CD1 3.94Å; E75-L79 HydrophobicContact CG-CG 4.4Å; E75-L79 WeakPolarHBondContact O-CG 3.45Å; E75-L79 PolarHBondContact O-N 3.28Å
76	Y	87.9	Confident	86.3	Confident	27 Å²	27	21.2 Å²	21.2	11%	0.106	11%	0.114	C	C	.	.	H	α-helix	trans	-63.9	-37.5	-178.5	-91.7	-91.6	0	0	0	112.7	G72 Y78 Y82 G83 W86 Y405	G72-Y76 WeakPolarHBondContact O-CD2 3.48Å; G72-Y76 PolarHBondContact O-N 2.98Å; Y76-Y78 VanDerWaalsContact C-N 3.31Å; Y76-Y82 AromaticContact CD1-CD1 3.83Å; Y76-Y82 HydrophobicContact CD1-CD1 3.83Å; Y76-Y82 HydrophobicContact CD1-CD2 4.48Å; Y76-Y82 HydrophobicContact CD1-CE1 4.49Å; Y76-Y82 AromaticContact CD1-CG 3.81Å; Y76-Y82 HydrophobicContact CD1-CG 3.81Å; Y76-Y82 AromaticContact CE1-CD1 3.54Å; Y76-Y82 HydrophobicContact CE1-CD1 3.54Å; Y76-Y82 HydrophobicContact CE1-CD2 4.38Å; Y76-Y82 AromaticContact CE1-CE1 3.76Å; Y76-Y82 HydrophobicContact CE1-CE1 3.76Å; Y76-Y82 AromaticContact CE1-CG 3.86Å; Y76-Y82 HydrophobicContact CE1-CG 3.86Å; Y76-Y82 WeakPolarHBondContact O-CB 3.31Å; Y76-G83 CarbonylContact O-C 3.47Å; Y76-G83 VanDerWaalsContact O-CA 3.24Å; Y76-G83 WeakPolarHBondContact O-CA 3.44Å; Y76-G83 PolarHBondContact O-N 3.21Å; Y76-W86 HydrophobicContact CD1-CB 3.86Å; Y76-W86 HydrophobicContact CE1-CB 4.39Å; Y76-Y405 AromaticContact CE2-CD2 3.84Å; Y76-Y405 HydrophobicContact CE2-CD2 3.84Å; Y76-Y405 AromaticContact CE2-CE2 3.37Å; Y76-Y405 HydrophobicContact CE2-CE2 3.37Å; Y76-Y405 AromaticContact CE2-CZ 3.83Å; Y76-Y405 AromaticContact CZ-CE2 3.79Å; Y76-Y405 AromaticContact CZ-CZ 3.73Å; Y76-Y405 WeakPolarHBondContact OH-CE1 3.37Å; Y76-Y405 WeakPolarHBondContact OH-CE2 3.34Å; Y76-Y405 PolarHBondContact OH-OH 3.23Å
77	V	93.3	Very high	86.8	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-68.4	-33.8	174.5	178	0	0	0	0	111.4	T73 A74 E75 L84 A87 W230 V291 A295	T73-V77 VanDerWaalsContact O-CG2 3.24Å; T73-V77 WeakPolarHBondContact O-CG2 3.35Å; T73-V77 PolarHBondContact O-N 2.84Å; A74-V77 PolarHBondContact O-N 3.12Å; E75-V77 VanDerWaalsContact C-N 3.32Å; E75-V77 PolarHBondContact O-N 3.32Å; V77-L84 HydrophobicContact CG2-CB 4.45Å; V77-L84 HydrophobicContact CG2-CD1 4.16Å; V77-A87 HydrophobicContact CG2-CB 3.91Å; V77-W230 HydrophobicContact CG1-CB 4.35Å; V77-W230 HydrophobicContact CG1-CE3 3.99Å; V77-V291 HydrophobicContact CG2-CB 4.44Å; V77-V291 HydrophobicContact CG2-CG1 4.17Å; V77-V291 HydrophobicContact CG2-CG2 4.27Å; V77-A295 HydrophobicContact CG1-CB 4.07Å
78	Y	91.9	Very high	87.6	Confident	0 Å²	0	21.7 Å²	21.7	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-72.9	-35.6	178.4	171	-116.3	0	0	0	113.3	A74 E75 Y76 Q227 G297 A298 P312 K313 I321	A74-Y78 VanDerWaalsContact O-CB 3.28Å; A74-Y78 WeakPolarHBondContact O-CB 3.5Å; A74-Y78 PolarHBondContact O-N 3.33Å; E75-Y78 WeakPolarHBondContact O-CB 3.44Å; E75-Y78 PolarHBondContact O-N 2.72Å; E75-Y78 VanDerWaalsContact O-N 3.07Å; Y76-Y78 VanDerWaalsContact C-N 3.31Å; Y78-Q227 PolarHBondContact O-NE2 3.36Å; Y78-G297 VanDerWaalsContact CD2-C 3.49Å; Y78-G297 WeakPolarHBondContact CE2-O 3.07Å; Y78-A298 HydrophobicContact CD2-CB 4.26Å; Y78-P312 HydrophobicContact CE1-CB 4.37Å; Y78-P312 WeakPolarHBondContact OH-CD 3.33Å; Y78-K313 HydrophobicContact CE1-CB 3.82Å; Y78-K313 WeakPolarHBondContact OH-CB 3.19Å; Y78-K313 PolarHBondContact OH-N 3.44Å; Y78-I321 HydrophobicContact CD1-CB 4.01Å; Y78-I321 HydrophobicContact CD1-CD1 3.93Å; Y78-I321 HydrophobicContact CD1-CG1 3.81Å; Y78-I321 HydrophobicContact CD1-CG2 4.44Å; Y78-I321 HydrophobicContact CD2-CD1 3.83Å; Y78-I321 HydrophobicContact CD2-CG1 3.87Å; Y78-I321 HydrophobicContact CE1-CD1 3.84Å; Y78-I321 HydrophobicContact CE1-CG1 4.25Å; Y78-I321 HydrophobicContact CE2-CD1 3.76Å; Y78-I321 HydrophobicContact CE2-CG1 4.32Å; Y78-I321 HydrophobicContact CG-CB 4.19Å; Y78-I321 HydrophobicContact CG-CD1 3.92Å; Y78-I321 HydrophobicContact CG-CG1 3.59Å; Y78-I321 HydrophobicContact CG-CG2 4.42Å
79	L	88.8	Confident	88.2	Confident	34 Å²	34	22 Å²	22	18%	0.178	12%	0.117	C	C	.	.	S	Bend	trans	-70.2	132.4	-173.1	-74.5	167.7	0	0	0	112.6	E75 D81 Y82 G83	E75-L79 HydrophobicContact CG-CD1 3.94Å; E75-L79 HydrophobicContact CG-CG 4.4Å; E75-L79 WeakPolarHBondContact O-CG 3.45Å; E75-L79 PolarHBondContact O-N 3.28Å; L79-D81 VanDerWaalsContact C-N 3.33Å; L79-D81 PolarHBondContact O-N 3.34Å; L79-Y82 HydrophobicContact CB-CD2 3.64Å; L79-Y82 HydrophobicContact CB-CG 4.43Å; L79-Y82 HydrophobicContact CD1-CD2 3.66Å; L79-Y82 HydrophobicContact CD1-CE2 3.93Å; L79-Y82 HydrophobicContact CG-CD2 4.29Å; L79-Y82 PolarHBondContact O-N 3.43Å; L79-G83 PolarHBondContact O-N 3.48Å; L79-G83 VanDerWaalsContact O-N 3.13Å
80	P	84.8	Confident	88.5	Confident	32 Å²	32	21.9 Å²	21.9	21%	0.208	12%	0.118	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-31	-174.2	-24.9	33.3	0	0	0	116	Q227 S228 K313	P80-Q227 HydrophobicContact CG-CB 4.45Å; P80-S228 VanDerWaalsContact O-CB 3.28Å; P80-S228 WeakPolarHBondContact O-CB 3.4Å; P80-K313 HydrophobicContact CG-CD 4.19Å
81	D	83.5	Confident	88.7	Confident	119 Å²	119	27.5 Å²	27.5	64%	0.636	14%	0.142	S	C	*	.	T	Hydrogen-bonded Turn	trans	-85.9	-14.7	-177.5	-66.6	-49.8	0	0	0	113.2	L79	L79-D81 VanDerWaalsContact C-N 3.33Å; L79-D81 PolarHBondContact O-N 3.34Å
82	Y	85.3	Confident	89.1	Confident	69 Å²	69	27 Å²	27	27%	0.271	14%	0.14	S	C	.	.	T	Hydrogen-bonded Turn	trans	-109.6	-72.3	-171.9	-67.6	-73.9	0	0	0	111	Y76 L79 W86 G232	Y76-Y82 AromaticContact CD1-CD1 3.83Å; Y76-Y82 HydrophobicContact CD1-CD1 3.83Å; Y76-Y82 HydrophobicContact CD1-CD2 4.48Å; Y76-Y82 HydrophobicContact CD1-CE1 4.49Å; Y76-Y82 AromaticContact CD1-CG 3.81Å; Y76-Y82 HydrophobicContact CD1-CG 3.81Å; Y76-Y82 AromaticContact CE1-CD1 3.54Å; Y76-Y82 HydrophobicContact CE1-CD1 3.54Å; Y76-Y82 HydrophobicContact CE1-CD2 4.38Å; Y76-Y82 AromaticContact CE1-CE1 3.76Å; Y76-Y82 HydrophobicContact CE1-CE1 3.76Å; Y76-Y82 AromaticContact CE1-CG 3.86Å; Y76-Y82 HydrophobicContact CE1-CG 3.86Å; Y76-Y82 WeakPolarHBondContact O-CB 3.31Å; L79-Y82 HydrophobicContact CB-CD2 3.64Å; L79-Y82 HydrophobicContact CB-CG 4.43Å; L79-Y82 HydrophobicContact CD1-CD2 3.66Å; L79-Y82 HydrophobicContact CD1-CE2 3.93Å; L79-Y82 HydrophobicContact CG-CD2 4.29Å; L79-Y82 PolarHBondContact O-N 3.43Å; Y82-W86 HydrophobicContact CD1-CB 3.76Å; Y82-W86 AromaticContact CD1-CD2 3.71Å; Y82-W86 HydrophobicContact CD1-CD2 3.71Å; Y82-W86 HydrophobicContact CD1-CE3 4.04Å; Y82-W86 AromaticContact CD1-CG 3.63Å; Y82-W86 HydrophobicContact CD1-CG 3.63Å; Y82-W86 HydrophobicContact CE1-CD2 4.3Å; Y82-W86 HydrophobicContact CE1-CE3 4.25Å; Y82-W86 HydrophobicContact CG-CB 4.22Å; Y82-W86 HydrophobicContact CG-CG 4.35Å; Y82-G232 WeakPolarHBondContact O-CA 3.28Å
83	G	89.6	Confident	89.5	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.135	C	C	.	.	S	Bend	trans	63.9	-169.4	-173.2	0	0	0	0	0	114	Y76 L79 A85 W86 A87 W230	Y76-G83 CarbonylContact O-C 3.47Å; Y76-G83 VanDerWaalsContact O-CA 3.24Å; Y76-G83 WeakPolarHBondContact O-CA 3.44Å; Y76-G83 PolarHBondContact O-N 3.21Å; L79-G83 PolarHBondContact O-N 3.48Å; L79-G83 VanDerWaalsContact O-N 3.13Å; G83-A85 PolarHBondContact O-N 2.71Å; G83-W86 PolarHBondContact O-N 2.73Å; G83-A87 PolarHBondContact O-N 2.87Å; G83-W230 CarbonylContact C-O 3.12Å; G83-W230 WeakPolarHBondContact CA-O 3.32Å
84	L	91.8	Very high	89.7	Confident	47 Å²	47	26.9 Å²	26.9	25%	0.246	14%	0.137	C	C	.	.	G	3₁₀ helix	trans	-55.8	-34.6	179.8	-178.4	63.3	0	0	0	112.7	V77 W86 A87 W230 L231 V291	V77-L84 HydrophobicContact CG2-CB 4.45Å; V77-L84 HydrophobicContact CG2-CD1 4.16Å; L84-W86 PolarHBondContact O-N 2.94Å; L84-W86 VanDerWaalsContact O-N 3.11Å; L84-A87 HydrophobicContact CD1-CB 4.32Å; L84-A87 PolarHBondContact O-N 3.12Å; L84-A87 VanDerWaalsContact O-N 3.07Å; L84-W230 HydrophobicContact CB-CE3 4.36Å; L84-W230 HydrophobicContact CB-CZ3 4.39Å; L84-W230 HydrophobicContact CD2-CZ3 4.14Å; L84-W230 PolarHBondContact N-O 3.33Å; L84-L231 HydrophobicContact CD2-CD2 3.98Å; L84-L231 PolarHBondContact N-O 3.19Å; L84-V291 HydrophobicContact CD1-CG1 3.73Å; L84-V291 HydrophobicContact CD1-CG2 3.99Å
85	A	91.3	Very high	89.8	Confident	28 Å²	28	30 Å²	30	23%	0.231	15%	0.153	C	C	.	.	G	3₁₀ helix	trans	-56.7	-26.7	178.3	0	0	0	0	0	113.5	G83 L231 I234 W242	G83-A85 PolarHBondContact O-N 2.71Å; A85-L231 WeakPolarHBondContact CB-O 3.37Å; A85-L231 PolarHBondContact N-O 2.76Å; A85-I234 HydrophobicContact CB-CG1 4.03Å; A85-W242 PolarHBondContact O-NE1 3.26Å
86	W	89.4	Confident	90.1	Very high	21 Å²	21	28.6 Å²	28.6	8%	0.08	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-105.2	-4.4	179.1	-76.9	87.8	0	0	0	113.9	Y76 Y82 G83 L84 Q88 D238 L241 W242	Y76-W86 HydrophobicContact CD1-CB 3.86Å; Y76-W86 HydrophobicContact CE1-CB 4.39Å; Y82-W86 HydrophobicContact CD1-CB 3.76Å; Y82-W86 AromaticContact CD1-CD2 3.71Å; Y82-W86 HydrophobicContact CD1-CD2 3.71Å; Y82-W86 HydrophobicContact CD1-CE3 4.04Å; Y82-W86 AromaticContact CD1-CG 3.63Å; Y82-W86 HydrophobicContact CD1-CG 3.63Å; Y82-W86 HydrophobicContact CE1-CD2 4.3Å; Y82-W86 HydrophobicContact CE1-CE3 4.25Å; Y82-W86 HydrophobicContact CG-CB 4.22Å; Y82-W86 HydrophobicContact CG-CG 4.35Å; G83-W86 PolarHBondContact O-N 2.73Å; L84-W86 PolarHBondContact O-N 2.94Å; L84-W86 VanDerWaalsContact O-N 3.11Å; W86-Q88 PolarHBondContact O-N 3.04Å; W86-D238 HydrophobicContact CH2-CB 3.87Å; W86-D238 HydrophobicContact CZ2-CB 3.68Å; W86-L241 HydrophobicContact CH2-CD2 4.21Å; W86-L241 HydrophobicContact CH2-CG 4.37Å; W86-W242 AromaticContact CD2-CD1 3.78Å; W86-W242 AromaticContact CE3-CD1 3.8Å; W86-W242 HydrophobicContact CH2-CB 4.2Å; W86-W242 HydrophobicContact CZ3-CB 4.31Å
87	A	89.7	Confident	90.5	Very high	4 Å²	4	27.3 Å²	27.3	3%	0.033	14%	0.142	C	C	.	.			trans	-74.6	66.2	171.3	0	0	0	0	0	110.7	T73 V77 G83 L84 P90	T73-A87 HydrophobicContact CG2-CB 4.45Å; V77-A87 HydrophobicContact CG2-CB 3.91Å; G83-A87 PolarHBondContact O-N 2.87Å; L84-A87 HydrophobicContact CD1-CB 4.32Å; L84-A87 PolarHBondContact O-N 3.12Å; L84-A87 VanDerWaalsContact O-N 3.07Å; A87-P90 WeakPolarHBondContact O-CD 3.24Å
88	Q	89.5	Confident	90.6	Very high	10 Å²	10	29.4 Å²	29.4	5%	0.047	16%	0.155	C	C	.	.			trans	-75.1	-25.9	-174.4	-65.9	178.2	-0.4	0	0	113.2	W86 F91 G92 W242 N245 F246 L249	W86-Q88 PolarHBondContact O-N 3.04Å; Q88-F91 PolarHBondContact O-N 3.25Å; Q88-F91 VanDerWaalsContact O-N 3.17Å; Q88-G92 PolarHBondContact O-N 2.84Å; Q88-W242 HydrophobicContact CG-CZ2 3.86Å; Q88-W242 PolarHBondContact NE2-O 2.93Å; Q88-N245 VanDerWaalsContact OE1-C 3.28Å; Q88-F246 HydrophobicContact CB-CD2 4.22Å; Q88-F246 HydrophobicContact CG-CD2 4.3Å; Q88-F246 VanDerWaalsContact OE1-CA 3.27Å; Q88-L249 HydrophobicContact CB-CD1 3.73Å
89	A	87.1	Confident	90.8	Very high	10 Å²	10	31.3 Å²	31.3	8%	0.083	16%	0.164	C	C	.	.	H	α-helix	trans	-51.5	-47.3	-172.1	0	0	0	0	0	113.3	Y69 F91 G92 Y93 W408	Y69-A89 HydrophobicContact CD2-CB 4.43Å; A89-F91 PolarHBondContact O-N 2.86Å; A89-G92 PolarHBondContact O-N 3.45Å; A89-Y93 HydrophobicContact CB-CD2 4.19Å; A89-Y93 HydrophobicContact CB-CE2 4.08Å; A89-Y93 WeakPolarHBondContact O-CD2 3.25Å; A89-Y93 PolarHBondContact O-N 3.42Å; A89-W408 HydrophobicContact CB-CH2 3.67Å; A89-W408 HydrophobicContact CB-CZ2 4.27Å
90	P	91.1	Very high	91	Very high	4 Å²	4	29.7 Å²	29.7	3%	0.026	16%	0.156	C	C	.	.	H	α-helix	trans	-59.6	-45.9	179.7	-27	38.4	0	0	0	114.4	Y69 T73 A87 A94 L284 A287	Y69-P90 HydrophobicContact CE2-CB 4.43Å; Y69-P90 HydrophobicContact CE2-CG 4.46Å; Y69-P90 VanDerWaalsContact OH-CA 3.22Å; Y69-P90 WeakPolarHBondContact OH-CA 3.31Å; Y69-P90 WeakPolarHBondContact OH-CB 3.24Å; T73-P90 HydrophobicContact CG2-CG 3.86Å; T73-P90 WeakPolarHBondContact OG1-CG 3.42Å; A87-P90 WeakPolarHBondContact O-CD 3.24Å; P90-A94 WeakPolarHBondContact O-CB 3.5Å; P90-A94 PolarHBondContact O-N 3.48Å; P90-A94 VanDerWaalsContact O-N 3.16Å; P90-L284 HydrophobicContact CB-CD2 4.47Å; P90-A287 HydrophobicContact CB-CB 3.54Å; P90-A287 HydrophobicContact CG-CB 3.6Å
91	F	92	Very high	91.4	Very high	119 Å²	119	28.1 Å²	28.1	52%	0.522	15%	0.146	S	C	.	.	H	α-helix	trans	-74.8	-41.1	-178.1	-58.9	-76.8	0	0	0	111.8	Q88 A89 L95 F246 L284	Q88-F91 PolarHBondContact O-N 3.25Å; Q88-F91 VanDerWaalsContact O-N 3.17Å; A89-F91 PolarHBondContact O-N 2.86Å; F91-L95 WeakPolarHBondContact O-CB 3.31Å; F91-L95 PolarHBondContact O-N 3.35Å; F91-F246 HydrophobicContact CB-CE2 4.24Å; F91-L284 HydrophobicContact CD1-CD2 4.07Å; F91-L284 HydrophobicContact CE1-CD2 4.35Å
92	G	92	Very high	91.9	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-60.6	-52.5	178.4	0	0	0	0	0	112	Q88 A89 L95 S96 M250	Q88-G92 PolarHBondContact O-N 2.84Å; A89-G92 PolarHBondContact O-N 3.45Å; G92-L95 PolarHBondContact O-N 3.48Å; G92-S96 PolarHBondContact O-N 3.19Å; G92-M250 WeakPolarHBondContact O-CA 3.28Å
93	Y	90.6	Very high	92.2	Very high	3 Å²	3	28.7 Å²	28.7	1%	0.012	15%	0.148	C	C	.	.	H	α-helix	trans	-72.6	-33.2	-179.3	-67.2	-59.6	0	0	0	113.7	W64 Y69 A89 L95 S96 L97 L249 W408	W64-Y93 HydrophobicContact CD2-CD1 4.48Å; W64-Y93 AromaticContact CE3-CD1 3.5Å; W64-Y93 HydrophobicContact CE3-CD1 3.5Å; W64-Y93 VanDerWaalsContact CE3-CD1 3.5Å; W64-Y93 HydrophobicContact CE3-CD2 4.45Å; W64-Y93 AromaticContact CE3-CE1 3.92Å; W64-Y93 HydrophobicContact CE3-CE1 3.92Å; W64-Y93 AromaticContact CE3-CG 3.78Å; W64-Y93 HydrophobicContact CE3-CG 3.78Å; W64-Y93 AromaticContact CH2-CD1 3.83Å; W64-Y93 HydrophobicContact CH2-CD1 3.83Å; W64-Y93 HydrophobicContact CH2-CE1 4.01Å; W64-Y93 AromaticContact CZ3-CD1 3.13Å; W64-Y93 HydrophobicContact CZ3-CD1 3.13Å; W64-Y93 AromaticContact CZ3-CE1 3.23Å; W64-Y93 HydrophobicContact CZ3-CE1 3.23Å; W64-Y93 AromaticContact CZ3-CG 3.91Å; W64-Y93 HydrophobicContact CZ3-CG 3.91Å; Y69-Y93 AromaticContact CD2-CD2 3.95Å; Y69-Y93 HydrophobicContact CD2-CD2 3.95Å; Y69-Y93 HydrophobicContact CE2-CD2 4.08Å; A89-Y93 HydrophobicContact CB-CD2 4.19Å; A89-Y93 HydrophobicContact CB-CE2 4.08Å; A89-Y93 WeakPolarHBondContact O-CD2 3.25Å; A89-Y93 PolarHBondContact O-N 3.42Å; Y93-L95 VanDerWaalsContact C-N 3.28Å; Y93-L95 PolarHBondContact O-N 2.93Å; Y93-S96 WeakPolarHBondContact O-CB 3.25Å; Y93-S96 PolarHBondContact O-N 3.38Å; Y93-L97 WeakPolarHBondContact O-CG 3.09Å; Y93-L97 PolarHBondContact O-N 3.29Å; Y93-L249 HydrophobicContact CE1-CD2 4.4Å; Y93-L249 HydrophobicContact CE2-CD2 3.84Å; Y93-L249 VanDerWaalsContact OH-CD2 3.29Å; Y93-L249 WeakPolarHBondContact OH-CD2 3.47Å; Y93-W408 AromaticContact CE2-CH2 3.87Å; Y93-W408 HydrophobicContact CE2-CH2 3.87Å; Y93-W408 AromaticContact CE2-CZ2 3.44Å; Y93-W408 HydrophobicContact CE2-CZ2 3.44Å; Y93-W408 VanDerWaalsContact CE2-CZ2 3.44Å; Y93-W408 AromaticContact CZ-CZ2 3.82Å; Y93-W408 VanDerWaalsContact OH-CZ2 3.28Å; Y93-W408 WeakPolarHBondContact OH-CZ2 3.08Å
94	A	93.8	Very high	92.4	Very high	6 Å²	6	29 Å²	29	5%	0.05	15%	0.15	C	C	.	.	H	α-helix	trans	-60.3	-42.8	171.5	0	0	0	0	0	110.8	P90 L97 V98 A280 L284	P90-A94 WeakPolarHBondContact O-CB 3.5Å; P90-A94 PolarHBondContact O-N 3.48Å; P90-A94 VanDerWaalsContact O-N 3.16Å; A94-L97 PolarHBondContact O-N 3.43Å; A94-V98 WeakPolarHBondContact O-CG2 3.38Å; A94-V98 PolarHBondContact O-N 3.01Å; A94-A280 HydrophobicContact CB-CB 4.46Å; A94-A280 VanDerWaalsContact O-CB 3.32Å; A94-A280 WeakPolarHBondContact O-CB 3.23Å; A94-L284 HydrophobicContact CB-CD1 4.12Å; A94-L284 HydrophobicContact CB-CD2 3.76Å; A94-L284 HydrophobicContact CB-CG 3.68Å
95	L	95.3	Very high	92.4	Very high	65 Å²	65	26.8 Å²	26.8	34%	0.34	14%	0.138	S	C	.	.	H	α-helix	trans	-70.9	-36.1	176.9	-168.9	52.4	0	0	0	112.3	F91 G92 Y93 L97 V98 L99 F246 M250	F91-L95 WeakPolarHBondContact O-CB 3.31Å; F91-L95 PolarHBondContact O-N 3.35Å; G92-L95 PolarHBondContact O-N 3.48Å; Y93-L95 VanDerWaalsContact C-N 3.28Å; Y93-L95 PolarHBondContact O-N 2.93Å; L95-L97 VanDerWaalsContact C-N 3.33Å; L95-L97 PolarHBondContact O-N 3.15Å; L95-V98 HydrophobicContact CD1-CB 4.48Å; L95-V98 PolarHBondContact O-N 3.02Å; L95-L99 HydrophobicContact CD1-CG 4.28Å; L95-L99 HydrophobicContact CG-CD1 4.21Å; L95-L99 HydrophobicContact CG-CG 4.4Å; L95-L99 WeakPolarHBondContact O-CB 3.46Å; L95-L99 VanDerWaalsContact O-CG 3.3Å; L95-L99 WeakPolarHBondContact O-CG 3.25Å; L95-L99 PolarHBondContact O-N 2.85Å; L95-F246 HydrophobicContact CD2-CE1 4.49Å; L95-F246 HydrophobicContact CD2-CZ 4.33Å; L95-M250 HydrophobicContact CB-CG 4.13Å; L95-M250 HydrophobicContact CB-SD 4.3Å; L95-M250 HydrophobicContact CD2-CG 4.12Å; L95-M250 HydrophobicContact CD2-SD 3.21Å; L95-M250 WeakPolarHBondContact CD2-SD 3.12Å; L95-M250 HydrophobicContact CG-CG 3.92Å; L95-M250 HydrophobicContact CG-SD 3.55Å; L95-M250 VanDerWaalsContact CG-SD 3.55Å
96	S	94.3	Very high	92.3	Very high	2 Å²	2	30.7 Å²	30.7	1%	0.014	15%	0.149	C	C	.	.	H	α-helix	trans	-54.1	-48.5	169.7	177.6	0	0	0	0	111.4	G92 Y93 V98 L99 G100 M250 G253 I254	G92-S96 PolarHBondContact O-N 3.19Å; Y93-S96 WeakPolarHBondContact O-CB 3.25Å; Y93-S96 PolarHBondContact O-N 3.38Å; S96-V98 PolarHBondContact O-N 3.41Å; S96-L99 PolarHBondContact O-N 3.38Å; S96-G100 WeakPolarHBondContact O-CA 3.24Å; S96-G100 PolarHBondContact O-N 2.95Å; S96-M250 VanDerWaalsContact CA-O 3.25Å; S96-M250 WeakPolarHBondContact CA-O 3.42Å; S96-M250 WeakPolarHBondContact CB-O 3.22Å; S96-M250 PolarHBondContact OG-O 3.1Å; S96-G253 WeakPolarHBondContact OG-CA 3.29Å; S96-I254 WeakPolarHBondContact OG-CG1 3.38Å; S96-I254 PolarHBondContact OG-N 3.46Å
97	L	94.6	Very high	92.2	Very high	1 Å²	1	30 Å²	30	1%	0.005	15%	0.148	C	C	.	.	H	α-helix	trans	-63.5	-40.9	178.1	-77.7	171.2	0	0	0	112.4	M60 W64 Y93 A94 L95 G101 Y259 S276 A279 A280	M60-L97 HydrophobicContact CG-CD2 4.41Å; M60-L97 HydrophobicContact SD-CD2 4.42Å; W64-L97 HydrophobicContact CG-CD1 4.27Å; W64-L97 VanDerWaalsContact NE1-CD2 3.34Å; Y93-L97 WeakPolarHBondContact O-CG 3.09Å; Y93-L97 PolarHBondContact O-N 3.29Å; A94-L97 PolarHBondContact O-N 3.43Å; L95-L97 VanDerWaalsContact C-N 3.33Å; L95-L97 PolarHBondContact O-N 3.15Å; L97-G101 PolarHBondContact O-N 3.16Å; L97-Y259 HydrophobicContact CD2-CD2 3.59Å; L97-Y259 HydrophobicContact CD2-CE2 3.55Å; L97-S276 WeakPolarHBondContact O-CB 3.4Å; L97-A279 HydrophobicContact CD1-CB 3.9Å; L97-A279 HydrophobicContact CD2-CB 4.44Å; L97-A280 HydrophobicContact CB-CB 3.81Å; L97-A280 HydrophobicContact CD1-CB 4.45Å
98	V	95.9	Very high	92.2	Very high	44 Å²	44	29.9 Å²	29.9	27%	0.267	15%	0.146	S	C	.	.	H	α-helix	trans	-63.3	-49	175.1	171.5	0	0	0	0	111	A94 L95 S96 G101 L102 F277 A280	A94-V98 WeakPolarHBondContact O-CG2 3.38Å; A94-V98 PolarHBondContact O-N 3.01Å; L95-V98 HydrophobicContact CD1-CB 4.48Å; L95-V98 PolarHBondContact O-N 3.02Å; S96-V98 PolarHBondContact O-N 3.41Å; V98-G101 PolarHBondContact O-N 3.29Å; V98-L102 HydrophobicContact CG1-CD1 3.78Å; V98-L102 HydrophobicContact CG1-CG 4.44Å; V98-L102 WeakPolarHBondContact O-CB 3.45Å; V98-L102 VanDerWaalsContact O-CG 3.31Å; V98-L102 WeakPolarHBondContact O-CG 3.5Å; V98-L102 PolarHBondContact O-N 2.93Å; V98-F277 HydrophobicContact CG1-CD1 4.43Å; V98-F277 HydrophobicContact CG1-CE1 4.14Å; V98-F277 HydrophobicContact CG2-CD1 4.29Å; V98-A280 HydrophobicContact CG2-CB 3.64Å
99	L	95.7	Very high	92.2	Very high	39 Å²	39	29.7 Å²	29.7	20%	0.204	15%	0.146	C	C	.	.	H	α-helix	trans	-67.1	-42.6	-179.5	-67.5	176.8	0	0	0	111.8	L95 S96 G101 L102 F103 M250 L251 I254	L95-L99 HydrophobicContact CD1-CG 4.28Å; L95-L99 HydrophobicContact CG-CD1 4.21Å; L95-L99 HydrophobicContact CG-CG 4.4Å; L95-L99 WeakPolarHBondContact O-CB 3.46Å; L95-L99 VanDerWaalsContact O-CG 3.3Å; L95-L99 WeakPolarHBondContact O-CG 3.25Å; L95-L99 PolarHBondContact O-N 2.85Å; S96-L99 PolarHBondContact O-N 3.38Å; L99-G101 VanDerWaalsContact C-N 3.33Å; L99-G101 PolarHBondContact O-N 3.18Å; L99-L102 PolarHBondContact O-N 3.21Å; L99-F103 HydrophobicContact CD2-CD2 4.27Å; L99-F103 HydrophobicContact CD2-CE2 3.88Å; L99-F103 WeakPolarHBondContact O-CD2 3.43Å; L99-F103 PolarHBondContact O-N 3.39Å; L99-M250 HydrophobicContact CD1-CG 3.88Å; L99-M250 HydrophobicContact CD1-SD 3.8Å; L99-L251 HydrophobicContact CD1-CD2 4.25Å; L99-I254 HydrophobicContact CB-CD1 3.98Å
100	G	94.3	Very high	92	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.161	C	C	.	.	I	π-helix	trans	-54.6	-49	171.2	0	0	0	0	0	111.4	S96 F104 A105 Y259	S96-G100 WeakPolarHBondContact O-CA 3.24Å; S96-G100 PolarHBondContact O-N 2.95Å; G100-F104 CarbonylContact O-C 3.6Å; G100-F104 WeakPolarHBondContact O-CA 3.37Å; G100-F104 WeakPolarHBondContact O-CB 3.31Å; G100-F104 PolarHBondContact O-N 2.71Å; G100-A105 PolarHBondContact O-N 3.14Å; G100-Y259 PolarHBondContact O-OH 3.01Å
101	G	92.9	Very high	91.7	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	17%	0.174	C	C	.	.	I	π-helix	trans	-63.6	-45	178.1	0	0	0	0	0	113.5	L97 V98 L99 Y259 Q273	L97-G101 PolarHBondContact O-N 3.16Å; V98-G101 PolarHBondContact O-N 3.29Å; L99-G101 VanDerWaalsContact C-N 3.33Å; L99-G101 PolarHBondContact O-N 3.18Å; G101-Y259 PolarHBondContact N-OH 3.3Å; G101-Q273 VanDerWaalsContact O-CG 3.25Å; G101-Q273 WeakPolarHBondContact O-CG 3.31Å; G101-Q273 PolarHBondContact O-NE2 3.42Å
102	L	92.9	Very high	91.3	Very high	86 Å²	86	31.3 Å²	31.3	45%	0.45	16%	0.163	S	C	.	.	I	π-helix	trans	-66	-50	-178.9	-76.2	167.7	0	0	0	112.1	V98 L99 Q273 F277	V98-L102 HydrophobicContact CG1-CD1 3.78Å; V98-L102 HydrophobicContact CG1-CG 4.44Å; V98-L102 WeakPolarHBondContact O-CB 3.45Å; V98-L102 VanDerWaalsContact O-CG 3.31Å; V98-L102 WeakPolarHBondContact O-CG 3.5Å; V98-L102 PolarHBondContact O-N 2.93Å; L99-L102 PolarHBondContact O-N 3.21Å; L102-Q273 PolarHBondContact O-NE2 2.96Å; L102-F277 HydrophobicContact CD2-CE1 4.11Å; L102-F277 HydrophobicContact CD2-CZ 3.58Å; L102-F277 HydrophobicContact CG-CE1 3.78Å; L102-F277 HydrophobicContact CG-CZ 3.71Å
103	F	92.6	Very high	91.1	Very high	113 Å²	113	31.6 Å²	31.6	50%	0.496	16%	0.164	S	C	.	.	I	π-helix	trans	-104	-34.5	-166.4	-61.5	-68.8	0	0	0	113.9	L99 P107 F428	L99-F103 HydrophobicContact CD2-CD2 4.27Å; L99-F103 HydrophobicContact CD2-CE2 3.88Å; L99-F103 WeakPolarHBondContact O-CD2 3.43Å; L99-F103 PolarHBondContact O-N 3.39Å; F103-P107 VanDerWaalsContact O-CD 3.31Å; F103-P107 WeakPolarHBondContact O-CD 3.22Å; F103-P107 VanDerWaalsContact O-CG 3.24Å; F103-P107 WeakPolarHBondContact O-CG 3.4Å; F103-F428 HydrophobicContact CB-CZ 4.11Å; F103-F428 WeakPolarHBondContact O-CZ 3.38Å
104	F	93.6	Very high	90.8	Very high	8 Å²	8	31.7 Å²	31.7	4%	0.035	17%	0.165	C	C	.	.	I	π-helix	trans	-108.2	-30.5	-167.6	-58.7	-97.7	0	0	0	113.9	G100 K106 P107 M108 I254 F260 F420 L423 L424 L427 F428	G100-F104 CarbonylContact O-C 3.6Å; G100-F104 WeakPolarHBondContact O-CA 3.37Å; G100-F104 WeakPolarHBondContact O-CB 3.31Å; G100-F104 PolarHBondContact O-N 2.71Å; F104-K106 PolarHBondContact O-N 2.7Å; F104-P107 VanDerWaalsContact O-CD 3.24Å; F104-P107 WeakPolarHBondContact O-CD 3.32Å; F104-P107 VanDerWaalsContact O-CG 3.28Å; F104-P107 WeakPolarHBondContact O-CG 3.33Å; F104-M108 VanDerWaalsContact O-CB 3.25Å; F104-M108 WeakPolarHBondContact O-CB 3.46Å; F104-M108 WeakPolarHBondContact O-CG 3.45Å; F104-M108 PolarHBondContact O-N 3.34Å; F104-M108 VanDerWaalsContact O-N 3.16Å; F104-I254 HydrophobicContact CB-CG2 4.49Å; F104-I254 HydrophobicContact CD1-CG2 4.18Å; F104-I254 HydrophobicContact CD2-CG2 3.69Å; F104-I254 HydrophobicContact CE1-CG2 4.31Å; F104-I254 HydrophobicContact CE2-CD1 4.03Å; F104-I254 HydrophobicContact CE2-CG2 3.84Å; F104-I254 HydrophobicContact CG-CG2 3.87Å; F104-I254 HydrophobicContact CZ-CG2 4.14Å; F104-F260 HydrophobicContact CB-CE1 3.99Å; F104-F260 HydrophobicContact CB-CZ 3.75Å; F104-F260 HydrophobicContact CG-CZ 4.48Å; F104-F420 AromaticContact CZ-CE2 4Å; F104-F420 HydrophobicContact CZ-CE2 4Å; F104-L423 HydrophobicContact CD1-CD1 4.42Å; F104-L423 HydrophobicContact CD1-CD2 3.38Å; F104-L423 HydrophobicContact CD1-CG 3.79Å; F104-L423 HydrophobicContact CE1-CD2 3.37Å; F104-L423 HydrophobicContact CE1-CG 3.66Å; F104-L423 HydrophobicContact CG-CD2 4.35Å; F104-L423 HydrophobicContact CZ-CD2 4.34Å; F104-L424 HydrophobicContact CE1-CD2 4.14Å; F104-L424 HydrophobicContact CZ-CD2 3.69Å; F104-L427 HydrophobicContact CD1-CD1 3.72Å; F104-L427 HydrophobicContact CE1-CD1 4.34Å; F104-F428 AromaticContact CD1-CE2 3.96Å; F104-F428 HydrophobicContact CD1-CE2 3.96Å; F104-F428 HydrophobicContact CD1-CZ 4.33Å; F104-F428 HydrophobicContact CE1-CD2 4.46Å; F104-F428 AromaticContact CE1-CE2 3.5Å; F104-F428 HydrophobicContact CE1-CE2 3.5Å; F104-F428 HydrophobicContact CE1-CZ 4.27Å; F104-F428 AromaticContact CZ-CE2 3.83Å; F104-F428 HydrophobicContact CZ-CE2 3.83Å
105	A	91.4	Very high	90.7	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	16%	0.163	C	C	.	.	I	π-helix	trans	-63.3	-46.4	-175.5	0	0	0	0	0	112.6	G100 R109 V263 A272 Q273	G100-A105 PolarHBondContact O-N 3.14Å; A105-R109 VanDerWaalsContact O-CB 3.24Å; A105-R109 WeakPolarHBondContact O-CB 3.27Å; A105-R109 PolarHBondContact O-N 3.48Å; A105-V263 HydrophobicContact CB-CG1 3.78Å; A105-V263 HydrophobicContact CB-CG2 4.29Å; A105-A272 HydrophobicContact CB-CB 4.28Å; A105-Q273 HydrophobicContact CB-CG 4.21Å
106	K	89.2	Confident	90.5	Very high	109 Å²	109	28.4 Å²	28.4	47%	0.474	15%	0.147	S	C	.	.	H	α-helix	trans	-59.4	-56.3	178.3	-179.5	175.8	-177.4	-178.5	0	112.9	F104 M108 R109 S110 A269 Q273	F104-K106 PolarHBondContact O-N 2.7Å; K106-M108 VanDerWaalsContact C-N 3.34Å; K106-M108 PolarHBondContact O-N 3.25Å; K106-R109 PolarHBondContact O-N 3.3Å; K106-S110 VanDerWaalsContact O-CB 3.31Å; K106-S110 WeakPolarHBondContact O-CB 3.32Å; K106-S110 PolarHBondContact O-N 3.08Å; K106-S110 PolarHBondContact O-OG 3.25Å; K106-S110 VanDerWaalsContact O-OG 3.07Å; K106-A269 HydrophobicContact CB-CB 4.47Å; K106-A269 HydrophobicContact CG-CB 4.1Å; K106-Q273 HydrophobicContact CB-CG 4.49Å
107	P	87.9	Confident	90.5	Very high	8 Å²	8	28.4 Å²	28.4	5%	0.052	15%	0.147	C	C	.	.	H	α-helix	trans	-65.7	-36.4	-176.8	25.6	-35.9	0	0	0	113.3	F103 F104 S110 R111 L542	F103-P107 VanDerWaalsContact O-CD 3.31Å; F103-P107 WeakPolarHBondContact O-CD 3.22Å; F103-P107 VanDerWaalsContact O-CG 3.24Å; F103-P107 WeakPolarHBondContact O-CG 3.4Å; F104-P107 VanDerWaalsContact O-CD 3.24Å; F104-P107 WeakPolarHBondContact O-CD 3.32Å; F104-P107 VanDerWaalsContact O-CG 3.28Å; F104-P107 WeakPolarHBondContact O-CG 3.33Å; P107-S110 PolarHBondContact O-OG 2.86Å; P107-R111 WeakPolarHBondContact O-CG 3.19Å; P107-R111 PolarHBondContact O-N 3.07Å; P107-L542 HydrophobicContact CB-CD1 3.36Å; P107-L542 HydrophobicContact CB-CD2 3.57Å; P107-L542 HydrophobicContact CB-CG 4.06Å; P107-L542 HydrophobicContact CG-CD1 3.7Å
108	M	90.3	Very high	90.2	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-66.1	-43.9	178.4	-69.1	-69.8	-70.8	0	0	111	F104 K106 Y113 M116 P119 F260 L264 L427	F104-M108 VanDerWaalsContact O-CB 3.25Å; F104-M108 WeakPolarHBondContact O-CB 3.46Å; F104-M108 WeakPolarHBondContact O-CG 3.45Å; F104-M108 PolarHBondContact O-N 3.34Å; F104-M108 VanDerWaalsContact O-N 3.16Å; K106-M108 VanDerWaalsContact C-N 3.34Å; K106-M108 PolarHBondContact O-N 3.25Å; M108-Y113 HydrophobicContact CB-CD2 4.49Å; M108-Y113 HydrophobicContact CE-CD2 4.09Å; M108-Y113 WeakPolarHBondContact O-CD2 3.46Å; M108-Y113 HydrophobicContact SD-CD2 3.69Å; M108-Y113 HydrophobicContact SD-CE2 3.99Å; M108-M116 HydrophobicContact CE-SD 3.61Å; M108-P119 HydrophobicContact CE-CG 4.02Å; M108-P119 HydrophobicContact SD-CG 3.91Å; M108-F260 HydrophobicContact CB-CD1 4.03Å; M108-F260 HydrophobicContact CB-CE1 3.95Å; M108-F260 HydrophobicContact CE-CD1 3.97Å; M108-F260 HydrophobicContact CE-CE1 4.22Å; M108-F260 HydrophobicContact CE-CG 4.16Å; M108-F260 HydrophobicContact CG-CD1 3.94Å; M108-F260 HydrophobicContact CG-CE1 3.49Å; M108-F260 VanDerWaalsContact CG-CE1 3.49Å; M108-F260 HydrophobicContact CG-CZ 4.14Å; M108-L264 HydrophobicContact CB-CD2 4.1Å; M108-L264 VanDerWaalsContact O-CD2 3.31Å; M108-L264 WeakPolarHBondContact O-CD2 3.18Å; M108-L427 HydrophobicContact CG-CD1 4.32Å; M108-L427 HydrophobicContact SD-CD1 4.13Å; M108-L427 HydrophobicContact SD-CD2 4.23Å
109	R	88.1	Confident	89.9	Confident	7 Å²	7	26.5 Å²	26.5	3%	0.026	14%	0.135	C	C	.	.	H	α-helix	trans	-74.6	-36.7	-179.3	-177.3	57.4	-174.3	80	2.4	113.5	A105 K106 R111 G112 L264 A266 S267 A269 A272	A105-R109 VanDerWaalsContact O-CB 3.24Å; A105-R109 WeakPolarHBondContact O-CB 3.27Å; A105-R109 PolarHBondContact O-N 3.48Å; K106-R109 PolarHBondContact O-N 3.3Å; R109-R111 VanDerWaalsContact C-N 3.31Å; R109-R111 PolarHBondContact O-N 3.44Å; R109-G112 PolarHBondContact O-N 2.82Å; R109-L264 WeakPolarHBondContact CD-O 3.34Å; R109-L264 PolarHBondContact NE-O 2.95Å; R109-A266 VanDerWaalsContact CZ-O 3.23Å; R109-A266 PolarHBondContact NE-O 3.06Å; R109-A266 PolarHBondContact NH2-O 3Å; R109-S267 PolarHBondContact NH2-O 3.39Å; R109-A269 HydrophobicContact CB-CB 4.39Å; R109-A269 HydrophobicContact CG-CB 4.4Å; R109-A272 HydrophobicContact CB-CB 4.41Å; R109-A272 HydrophobicContact CG-CB 4.46Å
110	S	84.3	Confident	89.7	Confident	58 Å²	58	24.7 Å²	24.7	41%	0.406	13%	0.126	S	C	.	.	H	α-helix	trans	-69.4	-28.5	-177.3	64	0	0	0	0	113.1	K106 P107 G112	K106-S110 VanDerWaalsContact O-CB 3.31Å; K106-S110 WeakPolarHBondContact O-CB 3.32Å; K106-S110 PolarHBondContact O-N 3.08Å; K106-S110 PolarHBondContact O-OG 3.25Å; K106-S110 VanDerWaalsContact O-OG 3.07Å; P107-S110 PolarHBondContact O-OG 2.86Å; S110-G112 VanDerWaalsContact C-N 3.26Å; S110-G112 PolarHBondContact O-N 3.21Å
111	R	83.9	Confident	89.5	Confident	80 Å²	80	25.1 Å²	25.1	30%	0.302	13%	0.128	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	1.4	176.8	-69.3	-171.3	177.8	174.6	1	114	P107 R109 Y113 A540	P107-R111 WeakPolarHBondContact O-CG 3.19Å; P107-R111 PolarHBondContact O-N 3.07Å; R109-R111 VanDerWaalsContact C-N 3.31Å; R109-R111 PolarHBondContact O-N 3.44Å; R111-Y113 VanDerWaalsContact C-N 3.26Å; R111-Y113 HydrophobicContact CB-CD1 4.33Å; R111-Y113 HydrophobicContact CB-CD2 4.08Å; R111-Y113 HydrophobicContact CB-CE1 3.95Å; R111-Y113 HydrophobicContact CB-CE2 3.7Å; R111-Y113 HydrophobicContact CB-CG 4.39Å; R111-Y113 WeakPolarHBondContact CD-OH 3.36Å; R111-Y113 HydrophobicContact CG-CE2 4.31Å; R111-Y113 PolarHBondContact NH1-OH 3.07Å; R111-Y113 PolarHBondContact O-N 3.49Å; R111-A540 PolarHBondContact NH1-O 3.34Å; R111-A540 PolarHBondContact NH2-O 3.4Å
112	G	82.8	Confident	89.1	Confident	28 Å²	28	30.2 Å²	30.2	29%	0.289	15%	0.152	S	C	.	.	T	Hydrogen-bonded Turn	trans	68.2	24.4	177	0	0	0	0	0	113.7	R49 R109 S110	R49-G112 PolarHBondContact NH2-O 2.9Å; R109-G112 PolarHBondContact O-N 2.82Å; S110-G112 VanDerWaalsContact C-N 3.26Å; S110-G112 PolarHBondContact O-N 3.21Å
113	Y	88.5	Confident	88.8	Confident	6 Å²	6	27 Å²	27	2%	0.024	14%	0.135	C	C	.	.			trans	-59.8	152	174.6	-60.7	-40.5	0	0	0	111.4	R49 M108 R111 D118 P119 Q122 L264	R49-Y113 PolarHBondContact NH1-O 2.82Å; R49-Y113 VanDerWaalsContact NH1-O 3.16Å; R49-Y113 PolarHBondContact NH2-O 3.13Å; M108-Y113 HydrophobicContact CB-CD2 4.49Å; M108-Y113 HydrophobicContact CE-CD2 4.09Å; M108-Y113 WeakPolarHBondContact O-CD2 3.46Å; M108-Y113 HydrophobicContact SD-CD2 3.69Å; M108-Y113 HydrophobicContact SD-CE2 3.99Å; R111-Y113 VanDerWaalsContact C-N 3.26Å; R111-Y113 HydrophobicContact CB-CD1 4.33Å; R111-Y113 HydrophobicContact CB-CD2 4.08Å; R111-Y113 HydrophobicContact CB-CE1 3.95Å; R111-Y113 HydrophobicContact CB-CE2 3.7Å; R111-Y113 HydrophobicContact CB-CG 4.39Å; R111-Y113 WeakPolarHBondContact CD-OH 3.36Å; R111-Y113 HydrophobicContact CG-CE2 4.31Å; R111-Y113 PolarHBondContact NH1-OH 3.07Å; R111-Y113 PolarHBondContact O-N 3.49Å; Y113-D118 HydrophobicContact CD1-CB 3.61Å; Y113-D118 HydrophobicContact CE1-CB 4.27Å; Y113-D118 HydrophobicContact CG-CB 4.02Å; Y113-P119 HydrophobicContact CD2-CB 4.5Å; Y113-P119 HydrophobicContact CD2-CG 4.36Å; Y113-P119 HydrophobicContact CE2-CB 3.81Å; Y113-P119 HydrophobicContact CE2-CG 4.14Å; Y113-Q122 VanDerWaalsContact CE1-OE1 3.27Å; Y113-Q122 PolarHBondContact OH-OE1 3.49Å; Y113-L264 WeakPolarHBondContact O-CD2 2.86Å
114	V	85.3	Confident	88.6	Confident	6 Å²	6	21.9 Å²	21.9	4%	0.036	11%	0.112	C	C	.	.	S	Bend	trans	-106.7	-34.4	176.1	-179.4	0	0	0	0	109.7	M45 V46 D118 L264	M45-V114 HydrophobicContact CB-CG1 4.08Å; M45-V114 HydrophobicContact SD-CG1 3.84Å; V46-V114 HydrophobicContact CG1-CG1 4.08Å; V114-D118 PolarHBondContact N-OD2 2.95Å; V114-L264 WeakPolarHBondContact O-CD1 3.37Å
115	T	91.4	Very high	88.2	Confident	0 Å²	0	23 Å²	23	0%	0	13%	0.125	C	C	.	.	S	Bend	trans	-129.7	160	177.7	70.2	0	0	0	0	111.7	L117 D118 R363 N364	T115-L117 PolarHBondContact O-N 3.37Å; T115-L117 PolarHBondContact OG1-N 2.92Å; T115-D118 PolarHBondContact N-OD2 3.22Å; T115-D118 WeakPolarHBondContact O-CB 3.44Å; T115-D118 PolarHBondContact O-N 3.37Å; T115-D118 PolarHBondContact OG1-N 3.09Å; T115-D118 PolarHBondContact OG1-OD1 2.87Å; T115-R363 HydrophobicContact CG2-CB 3.86Å; T115-R363 HydrophobicContact CG2-CG 3.89Å; T115-N364 WeakPolarHBondContact CB-OD1 3.36Å; T115-N364 WeakPolarHBondContact CG2-OD1 3.04Å; T115-N364 VanDerWaalsContact OG1-CG 3.3Å; T115-N364 PolarHBondContact OG1-ND2 3.06Å; T115-N364 PolarHBondContact OG1-OD1 2.76Å
116	M	91.8	Very high	88	Confident	2 Å²	2	27.3 Å²	27.3	1%	0.01	14%	0.144	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.7	-24.4	172.8	176.7	48.5	-173.6	0	0	112.8	M108 P119 F120 P255 Q257 F260 I419 L423	M108-M116 HydrophobicContact CE-SD 3.61Å; M116-P119 WeakPolarHBondContact O-CD 3.37Å; M116-P119 WeakPolarHBondContact O-CG 3.45Å; M116-F120 HydrophobicContact CE-CE2 3.95Å; M116-F120 HydrophobicContact CE-CZ 3.79Å; M116-P255 HydrophobicContact CE-CB 3.65Å; M116-Q257 HydrophobicContact CB-CB 4.29Å; M116-F260 HydrophobicContact CB-CB 4.23Å; M116-F260 HydrophobicContact CB-CD2 4.05Å; M116-F260 HydrophobicContact CB-CG 4.42Å; M116-F260 HydrophobicContact CE-CD2 4.29Å; M116-F260 HydrophobicContact CE-CE2 3.9Å; M116-F260 HydrophobicContact CG-CD2 3.78Å; M116-F260 HydrophobicContact CG-CE2 4.29Å; M116-F260 HydrophobicContact SD-CD2 3.26Å; M116-F260 WeakPolarHBondContact SD-CD2 3.12Å; M116-F260 HydrophobicContact SD-CE2 3.29Å; M116-F260 WeakPolarHBondContact SD-CE2 3.21Å; M116-F260 HydrophobicContact SD-CG 4.04Å; M116-F260 HydrophobicContact SD-CZ 4.13Å; M116-I419 HydrophobicContact CE-CG2 4.31Å; M116-L423 HydrophobicContact CE-CB 3.93Å; M116-L423 HydrophobicContact CE-CD1 3.27Å; M116-L423 HydrophobicContact CE-CD2 3.53Å; M116-L423 HydrophobicContact CE-CG 3.69Å; M116-L423 HydrophobicContact SD-CD1 3.87Å
117	L	92.3	Very high	87.9	Confident	1 Å²	1	32.3 Å²	32.3	1%	0.005	16%	0.16	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.3	-13.7	-179.4	-58	179.8	0	0	0	114.1	T115 F120 Q121 F133 A136 M360 N364	T115-L117 PolarHBondContact O-N 3.37Å; T115-L117 PolarHBondContact OG1-N 2.92Å; L117-F120 HydrophobicContact CB-CD2 4.31Å; L117-F120 HydrophobicContact CD2-CD2 3.55Å; L117-F120 HydrophobicContact CD2-CE2 3.82Å; L117-F120 WeakPolarHBondContact O-CB 3.48Å; L117-F120 PolarHBondContact O-N 2.97Å; L117-F120 VanDerWaalsContact O-N 3.08Å; L117-Q121 PolarHBondContact O-N 3.42Å; L117-F133 HydrophobicContact CD1-CB 3.71Å; L117-F133 HydrophobicContact CD1-CD2 3.69Å; L117-F133 HydrophobicContact CD1-CG 4.18Å; L117-A136 HydrophobicContact CD2-CB 4.42Å; L117-M360 HydrophobicContact CD1-CB 4.22Å; L117-M360 HydrophobicContact CD1-CG 4.19Å; L117-M360 HydrophobicContact CD1-SD 3.9Å; L117-M360 HydrophobicContact CG-CG 4.42Å; L117-M360 HydrophobicContact CG-SD 4.02Å; L117-N364 HydrophobicContact CB-CB 4.29Å; L117-N364 HydrophobicContact CD1-CB 4.24Å
118	D	89.6	Confident	88	Confident	5 Å²	5	32.2 Å²	32.2	3%	0.027	16%	0.159	C	C	.	.	H	α-helix	trans	-52.9	-49.3	177	-68.8	-16	0	0	0	113.2	Y113 V114 T115 F120 Q121 Q122 N364 Q368	Y113-D118 HydrophobicContact CD1-CB 3.61Å; Y113-D118 HydrophobicContact CE1-CB 4.27Å; Y113-D118 HydrophobicContact CG-CB 4.02Å; V114-D118 PolarHBondContact N-OD2 2.95Å; T115-D118 PolarHBondContact N-OD2 3.22Å; T115-D118 WeakPolarHBondContact O-CB 3.44Å; T115-D118 PolarHBondContact O-N 3.37Å; T115-D118 PolarHBondContact OG1-N 3.09Å; T115-D118 PolarHBondContact OG1-OD1 2.87Å; D118-F120 VanDerWaalsContact C-N 3.27Å; D118-F120 PolarHBondContact O-N 3.31Å; D118-Q121 PolarHBondContact O-N 3.42Å; D118-Q122 WeakPolarHBondContact O-CB 3.39Å; D118-Q122 WeakPolarHBondContact O-CG 3.35Å; D118-Q122 PolarHBondContact O-N 2.89Å; D118-N364 PolarHBondContact OD1-ND2 2.93Å; D118-Q368 PolarHBondContact OD1-NE2 3.4Å
119	P	90.3	Very high	87.9	Confident	1 Å²	1	32.2 Å²	32.2	1%	0.006	16%	0.159	C	C	.	.	H	α-helix	trans	-59.4	-37	176.7	23.4	-35.9	0	0	0	112.6	M108 Y113 M116 L123 V426 L427	M108-P119 HydrophobicContact CE-CG 4.02Å; M108-P119 HydrophobicContact SD-CG 3.91Å; Y113-P119 HydrophobicContact CD2-CB 4.5Å; Y113-P119 HydrophobicContact CD2-CG 4.36Å; Y113-P119 HydrophobicContact CE2-CB 3.81Å; Y113-P119 HydrophobicContact CE2-CG 4.14Å; M116-P119 WeakPolarHBondContact O-CD 3.37Å; M116-P119 WeakPolarHBondContact O-CG 3.45Å; P119-L123 PolarHBondContact O-N 3.49Å; P119-L123 VanDerWaalsContact O-N 3.09Å; P119-V426 HydrophobicContact CB-CG1 3.72Å; P119-V426 WeakPolarHBondContact O-CG1 3.44Å; P119-L427 HydrophobicContact CB-CD2 4.47Å
120	F	91.2	Very high	88	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-66.4	-42.9	176.9	-55.7	-47	0	0	0	112.2	M116 L117 D118 Q122 Y124 L132 I419 Q422 L423 V426	M116-F120 HydrophobicContact CE-CE2 3.95Å; M116-F120 HydrophobicContact CE-CZ 3.79Å; L117-F120 HydrophobicContact CB-CD2 4.31Å; L117-F120 HydrophobicContact CD2-CD2 3.55Å; L117-F120 HydrophobicContact CD2-CE2 3.82Å; L117-F120 WeakPolarHBondContact O-CB 3.48Å; L117-F120 PolarHBondContact O-N 2.97Å; L117-F120 VanDerWaalsContact O-N 3.08Å; D118-F120 VanDerWaalsContact C-N 3.27Å; D118-F120 PolarHBondContact O-N 3.31Å; F120-Q122 VanDerWaalsContact C-N 3.35Å; F120-Y124 HydrophobicContact CB-CD2 4.32Å; F120-Y124 HydrophobicContact CD1-CD2 4.42Å; F120-Y124 HydrophobicContact CD1-CE2 4.15Å; F120-Y124 WeakPolarHBondContact O-CA 3.44Å; F120-Y124 WeakPolarHBondContact O-CB 3.21Å; F120-Y124 PolarHBondContact O-N 3.08Å; F120-L132 HydrophobicContact CB-CD1 3.88Å; F120-L132 HydrophobicContact CD1-CD1 4.19Å; F120-L132 HydrophobicContact CD2-CD1 4.25Å; F120-L132 HydrophobicContact CG-CD1 3.87Å; F120-I419 HydrophobicContact CE2-CG2 3.96Å; F120-I419 HydrophobicContact CZ-CG2 3.99Å; F120-Q422 HydrophobicContact CD1-CB 4.34Å; F120-Q422 HydrophobicContact CE1-CB 3.8Å; F120-Q422 HydrophobicContact CZ-CB 4.3Å; F120-L423 HydrophobicContact CE1-CB 4.3Å; F120-L423 HydrophobicContact CE1-CD1 4.49Å; F120-L423 HydrophobicContact CZ-CB 3.99Å; F120-L423 HydrophobicContact CZ-CD1 4.19Å; F120-V426 HydrophobicContact CD1-CB 4.3Å; F120-V426 HydrophobicContact CD1-CG2 3.59Å; F120-V426 HydrophobicContact CE1-CB 4.39Å; F120-V426 HydrophobicContact CE1-CG2 3.97Å
121	Q	88.6	Confident	88.4	Confident	9 Å²	9	32.8 Å²	32.8	4%	0.042	16%	0.163	C	C	.	.	H	α-helix	trans	-70.1	-33.8	179.9	-77	-173.2	-54.3	0	0	112.8	L117 D118 G125 N364	L117-Q121 PolarHBondContact O-N 3.42Å; D118-Q121 PolarHBondContact O-N 3.42Å; Q121-G125 CarbonylContact O-C 3.49Å; Q121-G125 WeakPolarHBondContact O-CA 3.42Å; Q121-G125 PolarHBondContact O-N 3.48Å; Q121-G125 VanDerWaalsContact O-N 3.13Å; Q121-N364 PolarHBondContact NE2-O 3.12Å; Q121-N364 VanDerWaalsContact OE1-CA 3.27Å; Q121-N364 PolarHBondContact OE1-ND2 3.07Å
122	Q	85.8	Confident	88.8	Confident	108 Å²	108	29 Å²	29	51%	0.505	15%	0.148	S	C	.	.	H	α-helix	trans	-67.7	-43.6	175.2	-72.7	-179.1	6.6	0	0	111.9	Y113 D118 F120	Y113-Q122 VanDerWaalsContact CE1-OE1 3.27Å; Y113-Q122 PolarHBondContact OH-OE1 3.49Å; D118-Q122 WeakPolarHBondContact O-CB 3.39Å; D118-Q122 WeakPolarHBondContact O-CG 3.35Å; D118-Q122 PolarHBondContact O-N 2.89Å; F120-Q122 VanDerWaalsContact C-N 3.35Å
123	L	85.9	Confident	89.3	Confident	19 Å²	19	28.3 Å²	28.3	10%	0.099	14%	0.137	C	C	.	.	H	α-helix	trans	-85.6	-46.7	-176.7	-175.1	56.7	0	0	0	113.7	P119 V426 T432 I536 M537 A540	P119-L123 PolarHBondContact O-N 3.49Å; P119-L123 VanDerWaalsContact O-N 3.09Å; L123-V426 HydrophobicContact CB-CG1 4.14Å; L123-V426 HydrophobicContact CD2-CB 4.07Å; L123-V426 HydrophobicContact CD2-CG1 3.87Å; L123-V426 HydrophobicContact CD2-CG2 3.87Å; L123-T432 WeakPolarHBondContact CD2-OG1 3.26Å; L123-I536 HydrophobicContact CD1-CG2 3.61Å; L123-M537 HydrophobicContact CD1-CG 4.44Å; L123-A540 HydrophobicContact CD1-CB 3.75Å; L123-A540 HydrophobicContact CD2-CB 4.08Å; L123-A540 HydrophobicContact CG-CB 4.41Å
124	Y	87.6	Confident	89.6	Confident	5 Å²	5	31.7 Å²	31.7	2%	0.02	16%	0.155	C	C	.	.	H	α-helix	trans	-96.7	-5.5	-174.6	-53.4	-41.5	0	0	0	113.8	F120 M128 L132 Q422 S425 V426 T434 S437 N502	F120-Y124 HydrophobicContact CB-CD2 4.32Å; F120-Y124 HydrophobicContact CD1-CD2 4.42Å; F120-Y124 HydrophobicContact CD1-CE2 4.15Å; F120-Y124 WeakPolarHBondContact O-CA 3.44Å; F120-Y124 WeakPolarHBondContact O-CB 3.21Å; F120-Y124 PolarHBondContact O-N 3.08Å; Y124-M128 HydrophobicContact CD2-CG 4.36Å; Y124-M128 HydrophobicContact CG-CG 4.37Å; Y124-L132 HydrophobicContact CD2-CD1 4.1Å; Y124-L132 HydrophobicContact CE2-CD1 4.44Å; Y124-Q422 PolarHBondContact OH-OE1 3.49Å; Y124-S425 WeakPolarHBondContact OH-CB 3.31Å; Y124-V426 HydrophobicContact CD2-CG2 4.08Å; Y124-V426 HydrophobicContact CE1-CG2 4.11Å; Y124-V426 HydrophobicContact CE2-CG2 3.24Å; Y124-V426 VanDerWaalsContact OH-CG2 3.24Å; Y124-V426 WeakPolarHBondContact OH-CG2 3.43Å; Y124-T434 WeakPolarHBondContact CA-OG1 3.45Å; Y124-T434 VanDerWaalsContact O-CG2 3.28Å; Y124-T434 WeakPolarHBondContact O-CG2 3.28Å; Y124-T434 PolarHBondContact O-OG1 3.18Å; Y124-S437 VanDerWaalsContact CD2-OG 3.28Å; Y124-S437 WeakPolarHBondContact CD2-OG 3.45Å; Y124-S437 VanDerWaalsContact CE2-OG 3.29Å; Y124-S437 WeakPolarHBondContact CE2-OG 3.3Å; Y124-N502 PolarHBondContact OH-ND2 2.93Å
125	G	86.6	Confident	89.9	Confident	30 Å²	30	31.5 Å²	31.5	31%	0.309	15%	0.154	S	C	.	.	H	α-helix	trans	84.9	167.6	-178.7	0	0	0	0	0	114.2	Q121 R127 M128 G129	Q121-G125 CarbonylContact O-C 3.49Å; Q121-G125 WeakPolarHBondContact O-CA 3.42Å; Q121-G125 PolarHBondContact O-N 3.48Å; Q121-G125 VanDerWaalsContact O-N 3.13Å; G125-R127 PolarHBondContact O-N 3.44Å; G125-M128 PolarHBondContact O-N 3.31Å; G125-G129 PolarHBondContact O-N 2.81Å
126	K	86.1	Confident	90	Very high	91 Å²	91	32.1 Å²	32.1	40%	0.396	16%	0.159	S	C	.	.	H	α-helix	trans	-60	-39	-171.6	-67	167.4	175.8	172.7	0	113.7	G130 Q368	K126-G130 PolarHBondContact O-N 2.9Å; K126-Q368 VanDerWaalsContact CD-O 3.26Å; K126-Q368 WeakPolarHBondContact CD-O 3.44Å; K126-Q368 VanDerWaalsContact CE-O 3.22Å; K126-Q368 WeakPolarHBondContact CE-O 3.35Å
127	R	87.9	Confident	90	Very high	214 Å²	214	33.4 Å²	33.4	81%	0.808	17%	0.166	S	C	*	.	H	α-helix	trans	-65.8	-48.5	-179.1	-66.9	-178.9	-178.3	164.1	1.8	111.4	G125 G130 L131	G125-R127 PolarHBondContact O-N 3.44Å; R127-G130 PolarHBondContact O-N 2.89Å; R127-L131 PolarHBondContact O-N 3.24Å
128	M	89.8	Confident	89.9	Confident	6 Å²	6	36.6 Å²	36.6	3%	0.03	18%	0.181	C	C	.	.	H	α-helix	trans	-69.7	-39.6	-180	-171	65.2	-150.4	0	0	111.7	Y124 G125 G130 L131 L132 T434 S437 V438 Y441	Y124-M128 HydrophobicContact CD2-CG 4.36Å; Y124-M128 HydrophobicContact CG-CG 4.37Å; G125-M128 PolarHBondContact O-N 3.31Å; M128-G130 PolarHBondContact O-N 3.24Å; M128-L131 HydrophobicContact CE-CB 4.42Å; M128-L131 HydrophobicContact CE-CD2 3.79Å; M128-L131 HydrophobicContact CE-CG 4.32Å; M128-L131 WeakPolarHBondContact O-CB 3.24Å; M128-L131 PolarHBondContact O-N 2.95Å; M128-L131 HydrophobicContact SD-CB 4.38Å; M128-L131 HydrophobicContact SD-CD2 3.89Å; M128-L132 HydrophobicContact CE-CD1 4.25Å; M128-L132 HydrophobicContact CE-CD2 3.85Å; M128-L132 HydrophobicContact CE-CG 3.78Å; M128-L132 HydrophobicContact CG-CD1 4.31Å; M128-L132 WeakPolarHBondContact O-CG 3.37Å; M128-L132 PolarHBondContact O-N 2.88Å; M128-T434 HydrophobicContact CB-CG2 3.79Å; M128-T434 HydrophobicContact CG-CG2 4.2Å; M128-S437 WeakPolarHBondContact CE-OG 3.39Å; M128-S437 WeakPolarHBondContact CG-OG 3.43Å; M128-V438 HydrophobicContact CE-CG2 4.46Å; M128-V438 HydrophobicContact SD-CG2 3.49Å; M128-V438 WeakPolarHBondContact SD-CG2 3.43Å; M128-Y441 HydrophobicContact CE-CD2 4.22Å; M128-Y441 HydrophobicContact CE-CG 4.45Å
129	G	88.3	Confident	90	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-62.4	-33	172.5	0	0	0	0	0	113.1	G125 L132 F133	G125-G129 PolarHBondContact O-N 2.81Å; G129-L132 PolarHBondContact O-N 3.47Å; G129-F133 PolarHBondContact O-N 2.96Å
130	G	89.9	Confident	90	Very high	20 Å²	20	36.6 Å²	36.6	21%	0.206	18%	0.182	C	C	.	.	H	α-helix	trans	-66.1	-36	170	0	0	0	0	0	113.8	K126 R127 M128 F133	K126-G130 PolarHBondContact O-N 2.9Å; R127-G130 PolarHBondContact O-N 2.89Å; M128-G130 PolarHBondContact O-N 3.24Å; G130-F133 WeakPolarHBondContact O-CB 3.44Å; G130-F133 PolarHBondContact O-N 2.78Å
131	L	92.4	Very high	90	Very high	58 Å²	58	37.6 Å²	37.6	30%	0.304	19%	0.187	S	C	.	.	H	α-helix	trans	-67.8	-42.9	173.2	-176.7	62.6	0	0	0	111.5	R127 M128 F133 I134 P135 Y441	R127-L131 PolarHBondContact O-N 3.24Å; M128-L131 HydrophobicContact CE-CB 4.42Å; M128-L131 HydrophobicContact CE-CD2 3.79Å; M128-L131 HydrophobicContact CE-CG 4.32Å; M128-L131 WeakPolarHBondContact O-CB 3.24Å; M128-L131 PolarHBondContact O-N 2.95Å; M128-L131 HydrophobicContact SD-CB 4.38Å; M128-L131 HydrophobicContact SD-CD2 3.89Å; L131-F133 VanDerWaalsContact C-N 3.26Å; L131-F133 PolarHBondContact O-N 3.29Å; L131-I134 HydrophobicContact CD1-CD1 4.19Å; L131-I134 WeakPolarHBondContact O-CB 3.28Å; L131-I134 PolarHBondContact O-N 3.33Å; L131-P135 VanDerWaalsContact O-CD 3.28Å; L131-P135 WeakPolarHBondContact O-CD 3.44Å; L131-Y441 HydrophobicContact CD1-CE1 4.39Å; L131-Y441 HydrophobicContact CD1-CE2 4.32Å; L131-Y441 HydrophobicContact CD2-CD1 4.39Å; L131-Y441 HydrophobicContact CD2-CD2 4.3Å; L131-Y441 HydrophobicContact CD2-CE2 4.44Å; L131-Y441 HydrophobicContact CD2-CG 4.28Å; L131-Y441 HydrophobicContact CG-CD2 4.17Å; L131-Y441 HydrophobicContact CG-CE2 3.9Å
132	L	93.3	Very high	90	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-68.9	-22.4	177.2	-68	171.5	0	0	0	113	F120 Y124 M128 G129 I134 P135 I418 I419 Q422 Y441	F120-L132 HydrophobicContact CB-CD1 3.88Å; F120-L132 HydrophobicContact CD1-CD1 4.19Å; F120-L132 HydrophobicContact CD2-CD1 4.25Å; F120-L132 HydrophobicContact CG-CD1 3.87Å; Y124-L132 HydrophobicContact CD2-CD1 4.1Å; Y124-L132 HydrophobicContact CE2-CD1 4.44Å; M128-L132 HydrophobicContact CE-CD1 4.25Å; M128-L132 HydrophobicContact CE-CD2 3.85Å; M128-L132 HydrophobicContact CE-CG 3.78Å; M128-L132 HydrophobicContact CG-CD1 4.31Å; M128-L132 WeakPolarHBondContact O-CG 3.37Å; M128-L132 PolarHBondContact O-N 2.88Å; G129-L132 PolarHBondContact O-N 3.47Å; L132-I134 PolarHBondContact O-N 3.37Å; L132-P135 WeakPolarHBondContact O-CD 3.33Å; L132-P135 WeakPolarHBondContact O-CG 3.3Å; L132-I418 HydrophobicContact CD2-CG2 4.17Å; L132-I419 HydrophobicContact CB-CD1 4.18Å; L132-I419 HydrophobicContact CD2-CD1 3.96Å; L132-I419 WeakPolarHBondContact O-CD1 3.19Å; L132-Q422 HydrophobicContact CD1-CG 4.5Å; L132-Q422 HydrophobicContact CD2-CG 3.95Å; L132-Y441 HydrophobicContact CD2-CD2 4.02Å
133	F	93.8	Very high	90.1	Very high	13 Å²	13	33.7 Å²	33.7	6%	0.057	17%	0.168	C	C	.	.	H	α-helix	trans	-62.8	-30.8	171	171.2	-106.3	0	0	0	112.8	L117 G129 G130 L131 A136 L137 M360 F361 I365 F390	L117-F133 HydrophobicContact CD1-CB 3.71Å; L117-F133 HydrophobicContact CD1-CD2 3.69Å; L117-F133 HydrophobicContact CD1-CG 4.18Å; G129-F133 PolarHBondContact O-N 2.96Å; G130-F133 WeakPolarHBondContact O-CB 3.44Å; G130-F133 PolarHBondContact O-N 2.78Å; L131-F133 VanDerWaalsContact C-N 3.26Å; L131-F133 PolarHBondContact O-N 3.29Å; F133-A136 PolarHBondContact O-N 3.35Å; F133-L137 HydrophobicContact CD1-CB 4.49Å; F133-L137 HydrophobicContact CD2-CB 4.48Å; F133-L137 HydrophobicContact CE1-CB 4.04Å; F133-L137 HydrophobicContact CE1-CD2 3.66Å; F133-L137 HydrophobicContact CE1-CG 4.32Å; F133-L137 HydrophobicContact CE2-CB 4.02Å; F133-L137 HydrophobicContact CE2-CD1 4.47Å; F133-L137 HydrophobicContact CZ-CB 3.78Å; F133-L137 HydrophobicContact CZ-CD1 3.96Å; F133-L137 HydrophobicContact CZ-CD2 3.73Å; F133-L137 HydrophobicContact CZ-CG 4.02Å; F133-L137 VanDerWaalsContact O-CB 3.27Å; F133-L137 WeakPolarHBondContact O-CB 3.37Å; F133-L137 PolarHBondContact O-N 3.36Å; F133-M360 HydrophobicContact CD2-CB 3.87Å; F133-M360 HydrophobicContact CE2-CB 3.64Å; F133-F361 AromaticContact CE1-CD2 3.75Å; F133-F361 HydrophobicContact CE1-CD2 3.75Å; F133-F361 HydrophobicContact CE2-CB 4.19Å; F133-F361 HydrophobicContact CZ-CB 3.77Å; F133-F361 AromaticContact CZ-CD2 3.73Å; F133-F361 HydrophobicContact CZ-CD2 3.73Å; F133-F361 HydrophobicContact CZ-CG 4.26Å; F133-I365 HydrophobicContact CB-CD1 3.72Å; F133-I365 HydrophobicContact CB-CG1 4.24Å; F133-I365 HydrophobicContact CD1-CD1 3.76Å; F133-I365 HydrophobicContact CD1-CG1 3.55Å; F133-I365 HydrophobicContact CD2-CG1 4.19Å; F133-I365 HydrophobicContact CE1-CG1 3.88Å; F133-I365 HydrophobicContact CE2-CG1 4.48Å; F133-I365 HydrophobicContact CG-CD1 3.76Å; F133-I365 HydrophobicContact CG-CG1 3.71Å; F133-I365 HydrophobicContact CZ-CG1 4.34Å; F133-F390 HydrophobicContact CZ-CZ 4.37Å
134	I	92.8	Very high	90.3	Very high	78 Å²	78	33 Å²	33	40%	0.4	16%	0.164	S	C	.	.	H	α-helix	trans	-60.1	-57.8	-177.4	-59.1	177.8	0	0	0	111.9	L131 L132 A136 L137 M138	L131-I134 HydrophobicContact CD1-CD1 4.19Å; L131-I134 WeakPolarHBondContact O-CB 3.28Å; L131-I134 PolarHBondContact O-N 3.33Å; L132-I134 PolarHBondContact O-N 3.37Å; I134-A136 VanDerWaalsContact C-N 3.28Å; I134-A136 PolarHBondContact O-N 3.23Å; I134-L137 PolarHBondContact O-N 2.67Å; I134-M138 HydrophobicContact CG2-SD 4.09Å; I134-M138 WeakPolarHBondContact O-CG 3.32Å; I134-M138 PolarHBondContact O-N 3.49Å
135	P	92.3	Very high	90.3	Very high	2 Å²	2	32.7 Å²	32.7	1%	0.013	16%	0.163	C	C	.	.	H	α-helix	trans	-64.4	-31.1	177.6	24.2	-34.2	0	0	0	112.9	L131 L132 G139 L414 I418 I419 Y441	L131-P135 VanDerWaalsContact O-CD 3.28Å; L131-P135 WeakPolarHBondContact O-CD 3.44Å; L132-P135 WeakPolarHBondContact O-CD 3.33Å; L132-P135 WeakPolarHBondContact O-CG 3.3Å; P135-G139 PolarHBondContact O-N 2.8Å; P135-L414 HydrophobicContact CB-CB 4.12Å; P135-I418 HydrophobicContact CB-CD1 4.29Å; P135-I418 HydrophobicContact CG-CG2 4.16Å; P135-I419 HydrophobicContact CB-CD1 4.35Å; P135-I419 HydrophobicContact CB-CG1 4.49Å; P135-I419 HydrophobicContact CG-CD1 3.61Å; P135-I419 HydrophobicContact CG-CG1 4.27Å; P135-Y441 HydrophobicContact CG-CE2 3.98Å
136	A	93	Very high	90.1	Very high	13 Å²	13	31.3 Å²	31.3	11%	0.107	15%	0.149	C	C	.	.	H	α-helix	trans	-65.1	-45.4	174	0	0	0	0	0	111.9	L117 F133 I134 G139 E140 M360	L117-A136 HydrophobicContact CD2-CB 4.42Å; F133-A136 PolarHBondContact O-N 3.35Å; I134-A136 VanDerWaalsContact C-N 3.28Å; I134-A136 PolarHBondContact O-N 3.23Å; A136-G139 PolarHBondContact O-N 2.82Å; A136-E140 PolarHBondContact O-N 3.41Å; A136-E140 VanDerWaalsContact O-N 3.14Å; A136-M360 HydrophobicContact CB-CE 4.34Å; A136-M360 HydrophobicContact CB-SD 4.15Å
137	L	93.5	Very high	90.1	Very high	28 Å²	28	27 Å²	27	15%	0.147	13%	0.13	C	C	.	.	H	α-helix	trans	-64.2	-43.1	176	176.7	64.9	0	0	0	111.6	F133 I134 G139 E140 I141 A357 F390	F133-L137 HydrophobicContact CD1-CB 4.49Å; F133-L137 HydrophobicContact CD2-CB 4.48Å; F133-L137 HydrophobicContact CE1-CB 4.04Å; F133-L137 HydrophobicContact CE1-CD2 3.66Å; F133-L137 HydrophobicContact CE1-CG 4.32Å; F133-L137 HydrophobicContact CE2-CB 4.02Å; F133-L137 HydrophobicContact CE2-CD1 4.47Å; F133-L137 HydrophobicContact CZ-CB 3.78Å; F133-L137 HydrophobicContact CZ-CD1 3.96Å; F133-L137 HydrophobicContact CZ-CD2 3.73Å; F133-L137 HydrophobicContact CZ-CG 4.02Å; F133-L137 VanDerWaalsContact O-CB 3.27Å; F133-L137 WeakPolarHBondContact O-CB 3.37Å; F133-L137 PolarHBondContact O-N 3.36Å; I134-L137 PolarHBondContact O-N 2.67Å; L137-G139 VanDerWaalsContact C-N 3.27Å; L137-G139 PolarHBondContact O-N 3.21Å; L137-E140 PolarHBondContact O-N 3.14Å; L137-I141 HydrophobicContact CD1-CD1 3.9Å; L137-I141 HydrophobicContact CD1-CG1 4.09Å; L137-I141 HydrophobicContact CD2-CD1 4.23Å; L137-I141 HydrophobicContact CG-CD1 3.77Å; L137-I141 HydrophobicContact CG-CG1 4.31Å; L137-I141 WeakPolarHBondContact O-CG1 3.5Å; L137-I141 PolarHBondContact O-N 3.13Å; L137-A357 HydrophobicContact CD1-CB 3.83Å; L137-F390 HydrophobicContact CD1-CD1 3.99Å; L137-F390 HydrophobicContact CD1-CD2 4.13Å; L137-F390 HydrophobicContact CD1-CE1 3.76Å; L137-F390 HydrophobicContact CD1-CE2 3.88Å; L137-F390 HydrophobicContact CD1-CG 4.19Å; L137-F390 HydrophobicContact CD1-CZ 3.7Å; L137-F390 HydrophobicContact CD2-CE1 3.87Å; L137-F390 HydrophobicContact CD2-CZ 4.1Å; L137-F390 HydrophobicContact CG-CE1 4.45Å
138	M	90.3	Very high	90	Very high	68 Å²	68	16.8 Å²	16.8	34%	0.335	9%	0.091	S	C	.	.	H	α-helix	trans	-59.6	-41.4	176.1	-71.8	178.9	70.7	0	0	111.2	I134 I141 F142 L414	I134-M138 HydrophobicContact CG2-SD 4.09Å; I134-M138 WeakPolarHBondContact O-CG 3.32Å; I134-M138 PolarHBondContact O-N 3.49Å; M138-I141 PolarHBondContact O-N 3.2Å; M138-F142 HydrophobicContact CB-CE2 4.21Å; M138-F142 HydrophobicContact CB-CZ 4.48Å; M138-F142 HydrophobicContact CE-CE2 3.87Å; M138-F142 HydrophobicContact CE-CZ 3.62Å; M138-F142 WeakPolarHBondContact O-CB 3.47Å; M138-F142 WeakPolarHBondContact O-CD2 3.29Å; M138-F142 WeakPolarHBondContact O-CG 3.4Å; M138-F142 PolarHBondContact O-N 3.16Å; M138-L414 HydrophobicContact CB-CD1 4.38Å; M138-L414 HydrophobicContact CE-CD1 3.74Å; M138-L414 HydrophobicContact SD-CD1 3.96Å
139	G	90.3	Very high	89.7	Confident	2 Å²	2	17.2 Å²	17.2	2%	0.021	10%	0.095	C	C	.	.	H	α-helix	trans	-54.9	-52.1	172.8	0	0	0	0	0	112.2	P135 A136 L137 I141 F142 W143 S411	P135-G139 PolarHBondContact O-N 2.8Å; A136-G139 PolarHBondContact O-N 2.82Å; L137-G139 VanDerWaalsContact C-N 3.27Å; L137-G139 PolarHBondContact O-N 3.21Å; G139-I141 PolarHBondContact O-N 2.93Å; G139-F142 PolarHBondContact O-N 2.88Å; G139-W143 WeakPolarHBondContact O-CB 3.04Å; G139-W143 PolarHBondContact O-N 3.41Å; G139-S411 VanDerWaalsContact CA-O 3.3Å; G139-S411 WeakPolarHBondContact CA-O 3.27Å; G139-S411 VanDerWaalsContact O-CB 3.29Å; G139-S411 WeakPolarHBondContact O-CB 3.49Å
140	E	91.1	Very high	89.3	Confident	5 Å²	5	17.4 Å²	17.4	2%	0.023	10%	0.097	C	C	.	.	H	α-helix	trans	-63.4	-41.4	179.1	-63.7	-69.5	-178.7	0	0	112.9	A136 L137 W143 S144 V258 S353 S356 A357 M360	A136-E140 PolarHBondContact O-N 3.41Å; A136-E140 VanDerWaalsContact O-N 3.14Å; L137-E140 PolarHBondContact O-N 3.14Å; E140-W143 PolarHBondContact O-N 3.39Å; E140-S144 VanDerWaalsContact O-CB 3.22Å; E140-S144 WeakPolarHBondContact O-CB 3.35Å; E140-S144 PolarHBondContact O-N 3.43Å; E140-S144 PolarHBondContact O-OG 2.92Å; E140-V258 WeakPolarHBondContact OE1-CG2 3.48Å; E140-V258 VanDerWaalsContact OE2-CG2 3.32Å; E140-V258 WeakPolarHBondContact OE2-CG2 3.15Å; E140-S353 PolarHBondContact O-OG 2.83Å; E140-S353 VanDerWaalsContact O-OG 3.05Å; E140-S353 VanDerWaalsContact OE2-CA 3.31Å; E140-S353 WeakPolarHBondContact OE2-CA 3.32Å; E140-S353 WeakPolarHBondContact OE2-CB 3.49Å; E140-S353 PolarHBondContact OE2-OG 3.35Å; E140-S356 VanDerWaalsContact CD-OG 3.29Å; E140-S356 PolarHBondContact OE1-OG 3.17Å; E140-A357 HydrophobicContact CB-CB 3.88Å; E140-A357 HydrophobicContact CG-CB 4.21Å; E140-M360 HydrophobicContact CG-CE 3.84Å
141	I	90.5	Very high	88.9	Confident	21 Å²	21	16.5 Å²	16.5	11%	0.108	9%	0.087	C	C	.	.	H	α-helix	trans	-66.4	-45.2	179.1	-68.6	173.7	0	0	0	110.8	L137 M138 G139 W143 S144 A145 F390 L393 M397	L137-I141 HydrophobicContact CD1-CD1 3.9Å; L137-I141 HydrophobicContact CD1-CG1 4.09Å; L137-I141 HydrophobicContact CD2-CD1 4.23Å; L137-I141 HydrophobicContact CG-CD1 3.77Å; L137-I141 HydrophobicContact CG-CG1 4.31Å; L137-I141 WeakPolarHBondContact O-CG1 3.5Å; L137-I141 PolarHBondContact O-N 3.13Å; M138-I141 PolarHBondContact O-N 3.2Å; G139-I141 PolarHBondContact O-N 2.93Å; I141-W143 VanDerWaalsContact C-N 3.32Å; I141-S144 PolarHBondContact O-N 3.04Å; I141-A145 VanDerWaalsContact O-CB 3.25Å; I141-A145 WeakPolarHBondContact O-CB 3.39Å; I141-A145 PolarHBondContact O-N 3.35Å; I141-F390 HydrophobicContact CD1-CD1 4.37Å; I141-L393 HydrophobicContact CD1-CD1 4.32Å; I141-M397 HydrophobicContact CG2-CG 4.31Å
142	F	88.3	Confident	88.3	Confident	27 Å²	27	13.8 Å²	13.8	12%	0.118	7%	0.073	C	C	.	.	H	α-helix	trans	-65.1	-39	178.2	-65.6	-20.1	0	0	0	111.4	M138 G139 A145 A146 M397 L407 L410	M138-F142 HydrophobicContact CB-CE2 4.21Å; M138-F142 HydrophobicContact CB-CZ 4.48Å; M138-F142 HydrophobicContact CE-CE2 3.87Å; M138-F142 HydrophobicContact CE-CZ 3.62Å; M138-F142 WeakPolarHBondContact O-CB 3.47Å; M138-F142 WeakPolarHBondContact O-CD2 3.29Å; M138-F142 WeakPolarHBondContact O-CG 3.4Å; M138-F142 PolarHBondContact O-N 3.16Å; G139-F142 PolarHBondContact O-N 2.88Å; F142-A145 PolarHBondContact O-N 3.3Å; F142-A146 PolarHBondContact O-N 3.49Å; F142-M397 HydrophobicContact CD1-CE 4.49Å; F142-M397 HydrophobicContact CE1-CE 4.15Å; F142-L407 HydrophobicContact CD1-CD2 4.22Å; F142-L410 HydrophobicContact CD2-CB 3.8Å; F142-L410 HydrophobicContact CE2-CB 4.21Å; F142-L410 HydrophobicContact CG-CB 4.44Å
143	W	88.2	Confident	87.6	Confident	8 Å²	8	14.1 Å²	14.1	3%	0.03	8%	0.076	C	C	.	.	H	α-helix	trans	-65.9	-49.5	175.6	-171.8	35.7	0	0	0	112.1	T63 G139 E140 I141 A145 A146 I147 W256 V258 S353 W408	T63-W143 HydrophobicContact CG2-CH2 4.31Å; T63-W143 WeakPolarHBondContact O-CH2 3.4Å; G139-W143 WeakPolarHBondContact O-CB 3.04Å; G139-W143 PolarHBondContact O-N 3.41Å; E140-W143 PolarHBondContact O-N 3.39Å; I141-W143 VanDerWaalsContact C-N 3.32Å; W143-A145 VanDerWaalsContact C-N 3.26Å; W143-A145 PolarHBondContact O-N 3.43Å; W143-A146 WeakPolarHBondContact O-CB 3.45Å; W143-A146 PolarHBondContact O-N 3.45Å; W143-A146 VanDerWaalsContact O-N 3.15Å; W143-I147 HydrophobicContact CD2-CD1 3.6Å; W143-I147 VanDerWaalsContact CE2-CD1 3.44Å; W143-I147 HydrophobicContact CE3-CD1 4.23Å; W143-I147 HydrophobicContact CG-CD1 3.82Å; W143-I147 HydrophobicContact CZ2-CD1 3.96Å; W143-I147 WeakPolarHBondContact O-CD1 3.38Å; W143-I147 VanDerWaalsContact O-CG1 3.26Å; W143-I147 WeakPolarHBondContact O-CG1 3.43Å; W143-I147 PolarHBondContact O-N 2.83Å; W143-W256 HydrophobicContact CB-CH2 3.76Å; W143-W256 HydrophobicContact CB-CZ2 4.47Å; W143-W256 HydrophobicContact CB-CZ3 4.48Å; W143-W256 AromaticContact CD1-CH2 3.92Å; W143-W256 HydrophobicContact CD2-CE3 4.34Å; W143-W256 AromaticContact CD2-CH2 3.25Å; W143-W256 HydrophobicContact CD2-CH2 3.25Å; W143-W256 AromaticContact CD2-CZ3 3.14Å; W143-W256 HydrophobicContact CD2-CZ3 3.14Å; W143-W256 AromaticContact CE2-CH2 3.73Å; W143-W256 AromaticContact CE2-CZ3 3.47Å; W143-W256 VanDerWaalsContact CE2-CZ3 3.47Å; W143-W256 AromaticContact CE3-CE3 3.85Å; W143-W256 HydrophobicContact CE3-CE3 3.85Å; W143-W256 AromaticContact CE3-CH2 3.55Å; W143-W256 HydrophobicContact CE3-CH2 3.55Å; W143-W256 AromaticContact CE3-CZ3 3.02Å; W143-W256 HydrophobicContact CE3-CZ3 3.02Å; W143-W256 AromaticContact CG-CH2 3.37Å; W143-W256 HydrophobicContact CG-CH2 3.37Å; W143-W256 HydrophobicContact CG-CZ2 4.45Å; W143-W256 AromaticContact CG-CZ3 3.83Å; W143-W256 HydrophobicContact CG-CZ3 3.83Å; W143-W256 HydrophobicContact CH2-CE3 4.27Å; W143-W256 AromaticContact CH2-CZ3 3.62Å; W143-W256 HydrophobicContact CH2-CZ3 3.62Å; W143-W256 HydrophobicContact CZ2-CH2 4.41Å; W143-W256 AromaticContact CZ2-CZ3 3.71Å; W143-W256 HydrophobicContact CZ2-CZ3 3.71Å; W143-W256 AromaticContact CZ3-CE3 3.83Å; W143-W256 HydrophobicContact CZ3-CE3 3.83Å; W143-W256 HydrophobicContact CZ3-CH2 4.24Å; W143-W256 AromaticContact CZ3-CZ3 3.28Å; W143-W256 HydrophobicContact CZ3-CZ3 3.28Å; W143-V258 HydrophobicContact CE3-CG2 4.28Å; W143-V258 HydrophobicContact CZ3-CB 4.22Å; W143-V258 HydrophobicContact CZ3-CG1 4.28Å; W143-V258 HydrophobicContact CZ3-CG2 3.63Å; W143-S353 VanDerWaalsContact CE3-CB 3.43Å; W143-W408 AromaticContact CD1-CD1 3.64Å; W143-W408 AromaticContact NE1-CD1 3.89Å; W143-W408 AromaticContact NE1-NE1 3.91Å
144	S	89.4	Confident	86.8	Confident	3 Å²	3	13.5 Å²	13.5	2%	0.021	7%	0.073	C	C	.	.	H	α-helix	trans	-56.4	-40.4	175.4	-73.2	0	0	0	0	111.8	E140 I141 I147 L148 S353	E140-S144 VanDerWaalsContact O-CB 3.22Å; E140-S144 WeakPolarHBondContact O-CB 3.35Å; E140-S144 PolarHBondContact O-N 3.43Å; E140-S144 PolarHBondContact O-OG 2.92Å; I141-S144 PolarHBondContact O-N 3.04Å; S144-I147 PolarHBondContact O-N 3.2Å; S144-L148 WeakPolarHBondContact O-CB 3.35Å; S144-L148 VanDerWaalsContact O-CG 3.26Å; S144-L148 WeakPolarHBondContact O-CG 3.33Å; S144-L148 PolarHBondContact O-N 2.91Å; S144-S353 WeakPolarHBondContact OG-CB 3.38Å; S144-S353 PolarHBondContact OG-OG 3.41Å
145	A	87.7	Confident	86.2	Confident	0 Å²	0	10.2 Å²	10.2	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-65.1	-43.8	177.4	0	0	0	0	0	111.9	I141 F142 W143 I147 L148 S149 A394 M397 A398 L407	I141-A145 VanDerWaalsContact O-CB 3.25Å; I141-A145 WeakPolarHBondContact O-CB 3.39Å; I141-A145 PolarHBondContact O-N 3.35Å; F142-A145 PolarHBondContact O-N 3.3Å; W143-A145 VanDerWaalsContact C-N 3.26Å; W143-A145 PolarHBondContact O-N 3.43Å; A145-I147 VanDerWaalsContact C-N 3.33Å; A145-I147 PolarHBondContact O-N 3.39Å; A145-L148 PolarHBondContact O-N 2.84Å; A145-S149 WeakPolarHBondContact O-CB 3.39Å; A145-S149 PolarHBondContact O-N 2.86Å; A145-A394 WeakPolarHBondContact CA-O 3.46Å; A145-A394 HydrophobicContact CB-CB 4.41Å; A145-A394 VanDerWaalsContact CB-O 3.23Å; A145-A394 WeakPolarHBondContact CB-O 3.44Å; A145-M397 HydrophobicContact CB-CB 3.72Å; A145-A398 HydrophobicContact CB-CB 4.3Å; A145-A398 WeakPolarHBondContact O-CB 3.44Å; A145-L407 HydrophobicContact CB-CD1 3.52Å; A145-L407 HydrophobicContact CB-CD2 4.32Å; A145-L407 HydrophobicContact CB-CG 4.48Å
146	A	83.6	Confident	85.6	Confident	0 Å²	0	11 Å²	11	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-60.9	-45	175.9	0	0	0	0	0	111.1	F142 W143 S149 A150 V404 L407 W408	F142-A146 PolarHBondContact O-N 3.49Å; W143-A146 WeakPolarHBondContact O-CB 3.45Å; W143-A146 PolarHBondContact O-N 3.45Å; W143-A146 VanDerWaalsContact O-N 3.15Å; A146-S149 PolarHBondContact O-N 3.23Å; A146-A150 WeakPolarHBondContact O-CB 3.39Å; A146-A150 PolarHBondContact O-N 2.84Å; A146-V404 HydrophobicContact CB-CG1 4.2Å; A146-V404 WeakPolarHBondContact CB-O 3.41Å; A146-V404 WeakPolarHBondContact O-CG1 3.45Å; A146-L407 HydrophobicContact CB-CB 3.85Å; A146-W408 HydrophobicContact CB-CB 3.89Å
147	I	85.8	Confident	84.7	Confident	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-60.2	-52.8	177.2	-69.9	164.2	0	0	0	110.5	W143 S144 A145 S149 A150 L151 V346 S349 A350	W143-I147 HydrophobicContact CD2-CD1 3.6Å; W143-I147 VanDerWaalsContact CE2-CD1 3.44Å; W143-I147 HydrophobicContact CE3-CD1 4.23Å; W143-I147 HydrophobicContact CG-CD1 3.82Å; W143-I147 HydrophobicContact CZ2-CD1 3.96Å; W143-I147 WeakPolarHBondContact O-CD1 3.38Å; W143-I147 VanDerWaalsContact O-CG1 3.26Å; W143-I147 WeakPolarHBondContact O-CG1 3.43Å; W143-I147 PolarHBondContact O-N 2.83Å; S144-I147 PolarHBondContact O-N 3.2Å; A145-I147 VanDerWaalsContact C-N 3.33Å; A145-I147 PolarHBondContact O-N 3.39Å; I147-S149 VanDerWaalsContact C-N 3.27Å; I147-S149 PolarHBondContact O-N 2.9Å; I147-A150 PolarHBondContact O-N 3.28Å; I147-A150 VanDerWaalsContact O-N 3.17Å; I147-L151 PolarHBondContact O-N 3.17Å; I147-V346 HydrophobicContact CB-CG1 4.2Å; I147-V346 HydrophobicContact CG2-CB 4.4Å; I147-V346 HydrophobicContact CG2-CG1 3.33Å; I147-V346 WeakPolarHBondContact CG2-O 3.19Å; I147-V346 WeakPolarHBondContact O-CG1 3.1Å; I147-S349 VanDerWaalsContact CD1-CB 3.45Å; I147-A350 HydrophobicContact CG2-CB 3.71Å
148	L	86.9	Confident	83.7	Confident	0 Å²	0	10.2 Å²	10.2	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-61.9	-35.6	-179	-71.1	175.2	0	0	0	112.5	S144 A145 L151 G152 A171 A174 A350 A394 A398	S144-L148 WeakPolarHBondContact O-CB 3.35Å; S144-L148 VanDerWaalsContact O-CG 3.26Å; S144-L148 WeakPolarHBondContact O-CG 3.33Å; S144-L148 PolarHBondContact O-N 2.91Å; A145-L148 PolarHBondContact O-N 2.84Å; L148-L151 PolarHBondContact O-N 2.86Å; L148-G152 PolarHBondContact O-N 3.5Å; L148-A171 HydrophobicContact CD1-CB 4Å; L148-A171 HydrophobicContact CD2-CB 3.97Å; L148-A174 HydrophobicContact CD2-CB 4.32Å; L148-A350 HydrophobicContact CD2-CB 4.34Å; L148-A394 HydrophobicContact CD1-CB 4.08Å; L148-A398 HydrophobicContact CB-CB 4.33Å
149	S	82.8	Confident	82.9	Confident	15 Å²	15	7.4 Å²	7.4	11%	0.105	4%	0.043	C	C	.	.	H	α-helix	trans	-66.2	-45.6	174.3	-174.5	0	0	0	0	111.7	A145 A146 I147 L151 G152 A153 V404	A145-S149 WeakPolarHBondContact O-CB 3.39Å; A145-S149 PolarHBondContact O-N 2.86Å; A146-S149 PolarHBondContact O-N 3.23Å; I147-S149 VanDerWaalsContact C-N 3.27Å; I147-S149 PolarHBondContact O-N 2.9Å; S149-L151 VanDerWaalsContact C-N 3.32Å; S149-L151 PolarHBondContact O-N 2.59Å; S149-G152 PolarHBondContact O-N 2.86Å; S149-A153 PolarHBondContact O-N 2.75Å; S149-V404 VanDerWaalsContact OG-CG2 3.28Å; S149-V404 WeakPolarHBondContact OG-CG2 3.2Å
150	A	79.7	Confident	82.1	Confident	4 Å²	4	11.2 Å²	11.2	3%	0.033	6%	0.063	C	C	.	.	H	α-helix	trans	-61.8	-36.5	174.4	0	0	0	0	0	113.2	A146 I147 A153 T154 V346 V404	A146-A150 WeakPolarHBondContact O-CB 3.39Å; A146-A150 PolarHBondContact O-N 2.84Å; I147-A150 PolarHBondContact O-N 3.28Å; I147-A150 VanDerWaalsContact O-N 3.17Å; A150-A153 PolarHBondContact O-N 2.88Å; A150-T154 PolarHBondContact O-N 3.22Å; A150-T154 PolarHBondContact O-OG1 3.01Å; A150-V346 HydrophobicContact CB-CG1 4.29Å; A150-V404 HydrophobicContact CB-CG1 4.15Å
151	L	81.5	Confident	81.6	Confident	2 Å²	2	13.5 Å²	13.5	1%	0.01	8%	0.075	C	C	.	.	H	α-helix	trans	-67.5	-44.1	175.8	-174.5	50.6	0	0	0	110.6	I147 L148 S149 A153 T154 L155 V346	I147-L151 PolarHBondContact O-N 3.17Å; L148-L151 PolarHBondContact O-N 2.86Å; S149-L151 VanDerWaalsContact C-N 3.32Å; S149-L151 PolarHBondContact O-N 2.59Å; L151-A153 VanDerWaalsContact C-N 3.3Å; L151-A153 PolarHBondContact O-N 3.37Å; L151-T154 PolarHBondContact O-N 3.49Å; L151-L155 WeakPolarHBondContact O-CB 3.33Å; L151-L155 PolarHBondContact O-N 3.36Å; L151-V346 HydrophobicContact CB-CB 3.99Å; L151-V346 HydrophobicContact CB-CG1 3.56Å; L151-V346 HydrophobicContact CD1-CB 4.11Å; L151-V346 HydrophobicContact CG-CB 4.44Å; L151-V346 HydrophobicContact CG-CG1 4.46Å
152	G	80.9	Confident	81.3	Confident	0 Å²	0	17 Å²	17	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-57.7	-43	173.7	0	0	0	0	0	112.2	L148 S149 L155 S156 S166	L148-G152 PolarHBondContact O-N 3.5Å; S149-G152 PolarHBondContact O-N 2.86Å; G152-L155 PolarHBondContact O-N 2.92Å; G152-S156 WeakPolarHBondContact O-CB 3.2Å; G152-S156 PolarHBondContact O-N 3.42Å; G152-S156 PolarHBondContact O-OG 3.46Å; G152-S166 WeakPolarHBondContact O-CB 3.27Å
153	A	76.6	Confident	80.9	Confident	8 Å²	8	18.8 Å²	18.8	7%	0.066	10%	0.104	C	C	.	.	H	α-helix	trans	-61.9	-45.2	176.7	0	0	0	0	0	112	S149 A150 L151 L155 S156 V157 I163 M320	S149-A153 PolarHBondContact O-N 2.75Å; A150-A153 PolarHBondContact O-N 2.88Å; L151-A153 VanDerWaalsContact C-N 3.3Å; L151-A153 PolarHBondContact O-N 3.37Å; A153-L155 VanDerWaalsContact C-N 3.33Å; A153-L155 PolarHBondContact O-N 2.83Å; A153-S156 WeakPolarHBondContact CA-OG 3.36Å; A153-S156 PolarHBondContact O-N 3.3Å; A153-S156 PolarHBondContact O-OG 3.29Å; A153-V157 WeakPolarHBondContact O-CG2 3.44Å; A153-V157 PolarHBondContact O-N 3.01Å; A153-V157 VanDerWaalsContact O-N 3.16Å; A153-I163 HydrophobicContact CB-CD1 3.99Å; A153-M320 HydrophobicContact CB-CG 4.01Å; A153-M320 HydrophobicContact CB-SD 3.9Å
154	T	78.1	Confident	80.8	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-60.5	-45.1	176.1	-54	0	0	0	0	111	A150 L151 V157 I158 L339 V342 S343	A150-T154 PolarHBondContact O-N 3.22Å; A150-T154 PolarHBondContact O-OG1 3.01Å; L151-T154 PolarHBondContact O-N 3.49Å; T154-V157 PolarHBondContact O-N 3.15Å; T154-I158 HydrophobicContact CG2-CD1 4.01Å; T154-I158 VanDerWaalsContact O-CD1 3.27Å; T154-I158 WeakPolarHBondContact O-CD1 3.25Å; T154-I158 VanDerWaalsContact O-CG1 3.26Å; T154-I158 WeakPolarHBondContact O-CG1 3.4Å; T154-I158 PolarHBondContact O-N 2.87Å; T154-L339 HydrophobicContact CG2-CD2 4.39Å; T154-V342 HydrophobicContact CG2-CB 4.08Å; T154-V342 HydrophobicContact CG2-CG1 3.91Å; T154-S343 WeakPolarHBondContact CG2-OG 3.3Å
155	L	79.8	Confident	80.7	Confident	8 Å²	8	27.6 Å²	27.6	4%	0.042	15%	0.149	C	C	.	.	H	α-helix	trans	-70	-37	-179.4	-175.4	66.9	0	0	0	112.8	I11 L151 G152 A153 V157 I158 V159 I169 S170	I11-L155 HydrophobicContact CD1-CD1 3.56Å; I11-L155 HydrophobicContact CG2-CD1 4.3Å; L151-L155 WeakPolarHBondContact O-CB 3.33Å; L151-L155 PolarHBondContact O-N 3.36Å; G152-L155 PolarHBondContact O-N 2.92Å; A153-L155 VanDerWaalsContact C-N 3.33Å; A153-L155 PolarHBondContact O-N 2.83Å; L155-V157 VanDerWaalsContact C-N 3.3Å; L155-V157 PolarHBondContact O-N 3.28Å; L155-I158 PolarHBondContact O-N 3.17Å; L155-V159 HydrophobicContact CD1-CG2 3.67Å; L155-V159 HydrophobicContact CG-CG2 4.31Å; L155-V159 PolarHBondContact O-N 3.4Å; L155-I169 HydrophobicContact CD2-CG2 4.35Å; L155-S170 WeakPolarHBondContact CD2-OG 3.29Å
156	S	79.8	Confident	80.6	Confident	18 Å²	18	27.6 Å²	27.6	13%	0.126	15%	0.149	C	C	.	.	H	α-helix	trans	-63.9	-38.1	176.9	56.6	0	0	0	0	111.8	G152 A153 D160 I161 S166	G152-S156 WeakPolarHBondContact O-CB 3.2Å; G152-S156 PolarHBondContact O-N 3.42Å; G152-S156 PolarHBondContact O-OG 3.46Å; A153-S156 WeakPolarHBondContact CA-OG 3.36Å; A153-S156 PolarHBondContact O-N 3.3Å; A153-S156 PolarHBondContact O-OG 3.29Å; S156-D160 VanDerWaalsContact O-CA 3.25Å; S156-D160 WeakPolarHBondContact O-CA 3.13Å; S156-D160 PolarHBondContact O-N 3.01Å; S156-I161 VanDerWaalsContact CB-O 3.23Å; S156-I161 WeakPolarHBondContact CB-O 3.47Å; S156-I161 PolarHBondContact O-N 3.03Å; S156-S166 WeakPolarHBondContact CA-OG 3.02Å; S156-S166 PolarHBondContact N-OG 2.84Å
157	V	73.3	Confident	80.7	Confident	22 Å²	22	27.7 Å²	27.7	13%	0.133	15%	0.15	C	C	.	.	H	α-helix	trans	-66.3	-39.7	177.6	173.2	0	0	0	0	111.2	A153 T154 L155 M320 P323 Q327	A153-V157 WeakPolarHBondContact O-CG2 3.44Å; A153-V157 PolarHBondContact O-N 3.01Å; A153-V157 VanDerWaalsContact O-N 3.16Å; T154-V157 PolarHBondContact O-N 3.15Å; L155-V157 VanDerWaalsContact C-N 3.3Å; L155-V157 PolarHBondContact O-N 3.28Å; V157-M320 HydrophobicContact CG2-SD 4.25Å; V157-P323 HydrophobicContact CG1-CB 4.31Å; V157-Q327 HydrophobicContact CG1-CB 4.37Å; V157-Q327 PolarHBondContact O-NE2 2.84Å
158	I	73.3	Confident	80.9	Confident	3 Å²	3	30.5 Å²	30.5	2%	0.015	17%	0.167	C	C	.	.	H	α-helix	trans	-75.2	-44.8	-178.5	-57.4	153.7	0	0	0	112.2	I11 T154 L155 L339	I11-I158 HydrophobicContact CD1-CB 3.85Å; I11-I158 HydrophobicContact CD1-CD1 3.41Å; I11-I158 VanDerWaalsContact CD1-CD1 3.41Å; I11-I158 HydrophobicContact CD1-CG1 4.2Å; I11-I158 HydrophobicContact CD1-CG2 3.58Å; I11-I158 HydrophobicContact CG1-CD1 4.17Å; I11-I158 HydrophobicContact CG1-CG2 4.39Å; T154-I158 HydrophobicContact CG2-CD1 4.01Å; T154-I158 VanDerWaalsContact O-CD1 3.27Å; T154-I158 WeakPolarHBondContact O-CD1 3.25Å; T154-I158 VanDerWaalsContact O-CG1 3.26Å; T154-I158 WeakPolarHBondContact O-CG1 3.4Å; T154-I158 PolarHBondContact O-N 2.87Å; L155-I158 PolarHBondContact O-N 3.17Å; I158-L339 HydrophobicContact CD1-CB 3.65Å; I158-L339 HydrophobicContact CD1-CG 4.49Å; I158-L339 HydrophobicContact CG1-CB 3.79Å; I158-L339 HydrophobicContact CG1-CD1 3.71Å; I158-L339 HydrophobicContact CG1-CD2 4.37Å; I158-L339 HydrophobicContact CG1-CG 4.16Å
159	V	73.8	Confident	80.8	Confident	10 Å²	10	33.4 Å²	33.4	6%	0.061	18%	0.182	C	C	.	.	H	α-helix	trans	-95	-8.5	-169.9	-171.7	0	0	0	0	111.9	L8 I11 L155 I161	L8-V159 HydrophobicContact CD1-CG1 4.11Å; L8-V159 HydrophobicContact CD1-CG2 3.99Å; I11-V159 HydrophobicContact CD1-CG2 4.21Å; L155-V159 HydrophobicContact CD1-CG2 3.67Å; L155-V159 HydrophobicContact CG-CG2 4.31Å; L155-V159 PolarHBondContact O-N 3.4Å; V159-I161 VanDerWaalsContact C-N 3.31Å; V159-I161 HydrophobicContact CB-CD1 4.27Å; V159-I161 HydrophobicContact CB-CG1 4.03Å; V159-I161 HydrophobicContact CB-CG2 4.41Å; V159-I161 HydrophobicContact CG1-CD1 4.14Å; V159-I161 HydrophobicContact CG1-CG1 4.17Å; V159-I161 HydrophobicContact CG1-CG2 3.8Å; V159-I161 PolarHBondContact O-N 2.84Å
160	D	74.3	Confident	80.8	Confident	82 Å²	82	32.8 Å²	32.8	44%	0.439	18%	0.177	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.7	45.3	-176.6	-170.9	39.3	0	0	0	111.6	S156	S156-D160 VanDerWaalsContact O-CA 3.25Å; S156-D160 WeakPolarHBondContact O-CA 3.13Å; S156-D160 PolarHBondContact O-N 3.01Å
161	I	79.9	Confident	81.2	Confident	52 Å²	52	32.7 Å²	32.7	27%	0.267	18%	0.177	S	C	.	.			trans	-120.3	164	179.8	61	169.9	0	0	0	111.3	S156 V159 I163 S166 I169	S156-I161 VanDerWaalsContact CB-O 3.23Å; S156-I161 WeakPolarHBondContact CB-O 3.47Å; S156-I161 PolarHBondContact O-N 3.03Å; V159-I161 VanDerWaalsContact C-N 3.31Å; V159-I161 HydrophobicContact CB-CD1 4.27Å; V159-I161 HydrophobicContact CB-CG1 4.03Å; V159-I161 HydrophobicContact CB-CG2 4.41Å; V159-I161 HydrophobicContact CG1-CD1 4.14Å; V159-I161 HydrophobicContact CG1-CG1 4.17Å; V159-I161 HydrophobicContact CG1-CG2 3.8Å; V159-I161 PolarHBondContact O-N 2.84Å; I161-I163 PolarHBondContact O-N 3.3Å; I161-S166 WeakPolarHBondContact CD1-OG 3.39Å; I161-S166 VanDerWaalsContact CG1-OG 3.25Å; I161-S166 WeakPolarHBondContact CG1-OG 3.32Å; I161-I169 HydrophobicContact CD1-CD1 4.46Å
162	N	84.1	Confident	81.4	Confident	96 Å²	96	37.6 Å²	37.6	51%	0.513	20%	0.202	S	C	.	.			trans	-55.6	134.8	179.6	-176.5	-86.9	0	0	0	112.2	N164 M165 S166	N162-N164 VanDerWaalsContact C-N 3.33Å; N162-N164 PolarHBondContact O-N 3.02Å; N162-N164 VanDerWaalsContact OD1-CB 3.26Å; N162-N164 WeakPolarHBondContact OD1-CB 3.28Å; N162-N164 PolarHBondContact OD1-N 3.44Å; N162-M165 HydrophobicContact CB-CB 4.36Å; N162-M165 PolarHBondContact O-N 3.01Å; N162-M165 PolarHBondContact OD1-N 3.29Å; N162-S166 PolarHBondContact O-N 2.82Å; N162-S166 PolarHBondContact O-OG 3.27Å
163	I	80.2	Confident	81.4	Confident	64 Å²	64	40.1 Å²	40.1	33%	0.328	22%	0.215	S	C	.	.	H	α-helix	trans	-55.1	-44	-179.6	-177.3	62.5	0	0	0	112.6	A153 I161 M165 S166 V167	A153-I163 HydrophobicContact CB-CD1 3.99Å; I161-I163 PolarHBondContact O-N 3.3Å; I163-M165 VanDerWaalsContact C-N 3.34Å; I163-M165 PolarHBondContact O-N 3.48Å; I163-S166 WeakPolarHBondContact O-CB 3.42Å; I163-S166 PolarHBondContact O-N 3.32Å; I163-S166 VanDerWaalsContact O-N 3.11Å; I163-V167 HydrophobicContact CD1-CG2 4.46Å; I163-V167 WeakPolarHBondContact O-CG2 3.31Å; I163-V167 PolarHBondContact O-N 3.41Å
164	N	86.6	Confident	81.6	Confident	84 Å²	84	39.8 Å²	39.8	45%	0.449	21%	0.213	S	C	.	.	H	α-helix	trans	-65.5	-40	-178.1	-62.4	-18.5	0	0	0	111.2	N162 S166 V167 V168 L399	N162-N164 VanDerWaalsContact C-N 3.33Å; N162-N164 PolarHBondContact O-N 3.02Å; N162-N164 VanDerWaalsContact OD1-CB 3.26Å; N162-N164 WeakPolarHBondContact OD1-CB 3.28Å; N162-N164 PolarHBondContact OD1-N 3.44Å; N164-S166 VanDerWaalsContact C-N 3.32Å; N164-V167 PolarHBondContact O-N 2.88Å; N164-V168 WeakPolarHBondContact O-CG2 3.38Å; N164-V168 PolarHBondContact O-N 3.01Å; N164-V168 VanDerWaalsContact O-N 3.12Å; N164-L399 HydrophobicContact CB-CD2 3.77Å
165	M	86.2	Confident	81.9	Confident	112 Å²	112	40.4 Å²	40.4	55%	0.552	22%	0.216	S	C	*	.	H	α-helix	trans	-65	-39.7	174.9	-172.1	171.3	179.2	0	0	111.2	N162 I163 V168 I169	N162-M165 HydrophobicContact CB-CB 4.36Å; N162-M165 PolarHBondContact O-N 3.01Å; N162-M165 PolarHBondContact OD1-N 3.29Å; I163-M165 VanDerWaalsContact C-N 3.34Å; I163-M165 PolarHBondContact O-N 3.48Å; M165-V168 PolarHBondContact O-N 3.36Å; M165-I169 HydrophobicContact CE-CD1 4.09Å; M165-I169 HydrophobicContact CG-CD1 3.9Å; M165-I169 VanDerWaalsContact O-CG1 3.31Å; M165-I169 WeakPolarHBondContact O-CG1 3.47Å; M165-I169 PolarHBondContact O-N 3.31Å
166	S	85.3	Confident	82	Confident	0 Å²	0	45.8 Å²	45.8	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-62.6	-43.8	177	-58.6	0	0	0	0	112.4	G152 S156 I161 N162 I163 N164 S170	G152-S166 WeakPolarHBondContact O-CB 3.27Å; S156-S166 WeakPolarHBondContact CA-OG 3.02Å; S156-S166 PolarHBondContact N-OG 2.84Å; I161-S166 WeakPolarHBondContact CD1-OG 3.39Å; I161-S166 VanDerWaalsContact CG1-OG 3.25Å; I161-S166 WeakPolarHBondContact CG1-OG 3.32Å; N162-S166 PolarHBondContact O-N 2.82Å; N162-S166 PolarHBondContact O-OG 3.27Å; I163-S166 WeakPolarHBondContact O-CB 3.42Å; I163-S166 PolarHBondContact O-N 3.32Å; I163-S166 VanDerWaalsContact O-N 3.11Å; N164-S166 VanDerWaalsContact C-N 3.32Å; S166-S170 WeakPolarHBondContact O-CB 3.46Å; S166-S170 PolarHBondContact O-N 3.42Å; S166-S170 PolarHBondContact O-OG 3.23Å
167	V	87	Confident	81.8	Confident	2 Å²	2	45.4 Å²	45.4	1%	0.012	24%	0.235	C	C	.	.	H	α-helix	trans	-60.2	-47.3	175.4	173.4	0	0	0	0	110.7	I163 N164 S170 A171 T395 A398 L399	I163-V167 HydrophobicContact CD1-CG2 4.46Å; I163-V167 WeakPolarHBondContact O-CG2 3.31Å; I163-V167 PolarHBondContact O-N 3.41Å; N164-V167 PolarHBondContact O-N 2.88Å; V167-S170 PolarHBondContact O-N 3.06Å; V167-A171 WeakPolarHBondContact O-CB 3.3Å; V167-A171 PolarHBondContact O-N 3.35Å; V167-T395 HydrophobicContact CG1-CG2 4.37Å; V167-A398 HydrophobicContact CG1-CB 3.95Å; V167-L399 HydrophobicContact CB-CD2 3.99Å; V167-L399 HydrophobicContact CG1-CD2 3.99Å; V167-L399 HydrophobicContact CG1-CG 4.29Å
168	V	89.9	Confident	82	Confident	59 Å²	59	44.4 Å²	44.4	36%	0.358	23%	0.229	S	C	.	.	H	α-helix	trans	-63.4	-46.6	-179.2	172.4	0	0	0	0	111.9	N164 M165 S170 A171 L172 T395 L399	N164-V168 WeakPolarHBondContact O-CG2 3.38Å; N164-V168 PolarHBondContact O-N 3.01Å; N164-V168 VanDerWaalsContact O-N 3.12Å; M165-V168 PolarHBondContact O-N 3.36Å; V168-S170 VanDerWaalsContact C-N 3.31Å; V168-S170 PolarHBondContact O-N 3.39Å; V168-A171 PolarHBondContact O-N 3.16Å; V168-L172 HydrophobicContact CG1-CD1 4.16Å; V168-L172 WeakPolarHBondContact O-CG 3.41Å; V168-L172 PolarHBondContact O-N 3.28Å; V168-T395 HydrophobicContact CG2-CG2 4.48Å; V168-L399 HydrophobicContact CG2-CD1 3.92Å; V168-L399 HydrophobicContact CG2-CD2 4.47Å
169	I	84.6	Confident	82.3	Confident	61 Å²	61	46.4 Å²	46.4	31%	0.313	24%	0.239	S	C	.	.	H	α-helix	trans	-60.4	-45.9	178.4	-69.3	167.9	0	0	0	110.2	L155 I161 M165 A171 L172 I173	L155-I169 HydrophobicContact CD2-CG2 4.35Å; I161-I169 HydrophobicContact CD1-CD1 4.46Å; M165-I169 HydrophobicContact CE-CD1 4.09Å; M165-I169 HydrophobicContact CG-CD1 3.9Å; M165-I169 VanDerWaalsContact O-CG1 3.31Å; M165-I169 WeakPolarHBondContact O-CG1 3.47Å; M165-I169 PolarHBondContact O-N 3.31Å; I169-A171 PolarHBondContact O-N 3.32Å; I169-L172 PolarHBondContact O-N 2.91Å; I169-I173 HydrophobicContact CG2-CD1 3.97Å; I169-I173 WeakPolarHBondContact O-CG1 3.37Å; I169-I173 PolarHBondContact O-N 3.36Å; I169-I173 VanDerWaalsContact O-N 3.13Å
170	S	82.6	Confident	82.1	Confident	1 Å²	1	48.9 Å²	48.9	1%	0.007	25%	0.254	C	S	.	.	H	α-helix	trans	-61.9	-43.1	179.7	-62.8	0	0	0	0	112.3	L155 S166 V167 V168 I173 A174	L155-S170 WeakPolarHBondContact CD2-OG 3.29Å; S166-S170 WeakPolarHBondContact O-CB 3.46Å; S166-S170 PolarHBondContact O-N 3.42Å; S166-S170 PolarHBondContact O-OG 3.23Å; V167-S170 PolarHBondContact O-N 3.06Å; V168-S170 VanDerWaalsContact C-N 3.31Å; V168-S170 PolarHBondContact O-N 3.39Å; S170-I173 PolarHBondContact O-N 3.24Å; S170-A174 WeakPolarHBondContact O-CB 3.05Å; S170-A174 PolarHBondContact O-N 2.98Å
171	A	87.4	Confident	81.7	Confident	2 Å²	2	45.5 Å²	45.5	2%	0.017	24%	0.239	C	C	.	.	H	α-helix	trans	-64.3	-43.3	176.5	0	0	0	0	0	112.7	L148 V167 V168 I169 I173 A174 I175 T395	L148-A171 HydrophobicContact CD1-CB 4Å; L148-A171 HydrophobicContact CD2-CB 3.97Å; V167-A171 WeakPolarHBondContact O-CB 3.3Å; V167-A171 PolarHBondContact O-N 3.35Å; V168-A171 PolarHBondContact O-N 3.16Å; I169-A171 PolarHBondContact O-N 3.32Å; A171-I173 VanDerWaalsContact C-N 3.32Å; A171-I173 PolarHBondContact O-N 3.1Å; A171-A174 PolarHBondContact O-N 2.78Å; A171-I175 WeakPolarHBondContact O-CB 3.31Å; A171-I175 WeakPolarHBondContact O-CD1 3.37Å; A171-I175 WeakPolarHBondContact O-CG1 3.46Å; A171-I175 PolarHBondContact O-N 3.1Å; A171-T395 HydrophobicContact CB-CG2 3.86Å; A171-T395 WeakPolarHBondContact CB-OG1 3.47Å
172	L	86.8	Confident	81.5	Confident	105 Å²	105	43.4 Å²	43.4	55%	0.55	23%	0.23	S	C	.	.	H	α-helix	trans	-60.1	-43.8	177.9	-74.1	173.4	0	0	0	111.7	V168 I169 F176	V168-L172 HydrophobicContact CG1-CD1 4.16Å; V168-L172 WeakPolarHBondContact O-CG 3.41Å; V168-L172 PolarHBondContact O-N 3.28Å; I169-L172 PolarHBondContact O-N 2.91Å; L172-F176 VanDerWaalsContact O-CB 3.27Å; L172-F176 WeakPolarHBondContact O-CB 3.47Å; L172-F176 PolarHBondContact O-N 3.42Å
173	I	79.9	Confident	81.2	Confident	54 Å²	54	38.9 Å²	38.9	28%	0.277	21%	0.206	S	C	.	.	H	α-helix	trans	-62.8	-50.2	176.4	-65.5	170.3	0	0	0	109.3	Y15 I169 S170 A171 I175 F176 Y177 M347	Y15-I173 HydrophobicContact CD2-CD1 3.54Å; Y15-I173 HydrophobicContact CD2-CG2 4.33Å; Y15-I173 HydrophobicContact CE2-CD1 3.58Å; I169-I173 HydrophobicContact CG2-CD1 3.97Å; I169-I173 WeakPolarHBondContact O-CG1 3.37Å; I169-I173 PolarHBondContact O-N 3.36Å; I169-I173 VanDerWaalsContact O-N 3.13Å; S170-I173 PolarHBondContact O-N 3.24Å; A171-I173 VanDerWaalsContact C-N 3.32Å; A171-I173 PolarHBondContact O-N 3.1Å; I173-I175 PolarHBondContact O-N 3.43Å; I173-F176 PolarHBondContact O-N 3.29Å; I173-Y177 WeakPolarHBondContact O-CD1 3.5Å; I173-Y177 PolarHBondContact O-N 2.94Å; I173-M347 HydrophobicContact CG2-CE 3.87Å
174	A	80.1	Confident	81.1	Confident	1 Å²	1	37.5 Å²	37.5	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-56.4	-48.9	-179.8	0	0	0	0	0	113.3	L148 S170 A171 F176 Y177 T178 A350	L148-A174 HydrophobicContact CD2-CB 4.32Å; S170-A174 WeakPolarHBondContact O-CB 3.05Å; S170-A174 PolarHBondContact O-N 2.98Å; A171-A174 PolarHBondContact O-N 2.78Å; A174-F176 PolarHBondContact O-N 3.46Å; A174-Y177 VanDerWaalsContact CA-CE1 3.49Å; A174-Y177 HydrophobicContact CB-CE1 4.34Å; A174-Y177 WeakPolarHBondContact O-CD1 3.29Å; A174-Y177 WeakPolarHBondContact O-CE1 3.28Å; A174-T178 WeakPolarHBondContact O-CB 3.49Å; A174-T178 PolarHBondContact O-N 3.25Å; A174-T178 PolarHBondContact O-OG1 3.1Å; A174-A350 HydrophobicContact CB-CB 4.31Å
175	I	85.3	Confident	80.7	Confident	12 Å²	12	33.6 Å²	33.6	6%	0.062	18%	0.176	C	C	.	.	H	α-helix	trans	-63.4	-44.1	179	-67.3	165.1	0	0	0	110.4	A171 I173 Y177 T178 L179 I354 I387 F388	A171-I175 WeakPolarHBondContact O-CB 3.31Å; A171-I175 WeakPolarHBondContact O-CD1 3.37Å; A171-I175 WeakPolarHBondContact O-CG1 3.46Å; A171-I175 PolarHBondContact O-N 3.1Å; I173-I175 PolarHBondContact O-N 3.43Å; I175-Y177 PolarHBondContact O-N 2.82Å; I175-T178 PolarHBondContact O-N 3.18Å; I175-L179 HydrophobicContact CG2-CD1 4.02Å; I175-L179 HydrophobicContact CG2-CG 4.36Å; I175-L179 VanDerWaalsContact O-CG 3.27Å; I175-L179 WeakPolarHBondContact O-CG 3.39Å; I175-L179 PolarHBondContact O-N 3.29Å; I175-L179 VanDerWaalsContact O-N 3.07Å; I175-I354 HydrophobicContact CG1-CD1 4.37Å; I175-I387 HydrophobicContact CG2-CG2 4.33Å; I175-F388 HydrophobicContact CG2-CD2 4.11Å
176	F	82.1	Confident	80.5	Confident	122 Å²	122	28.3 Å²	28.3	54%	0.535	15%	0.15	S	C	.	.	H	α-helix	trans	-61.8	-48.4	-173.2	-174.6	-97.4	0	0	0	113.2	L19 L172 I173 A174 L179	L19-F176 HydrophobicContact CD1-CD1 4.35Å; L19-F176 HydrophobicContact CD1-CE1 4.46Å; L172-F176 VanDerWaalsContact O-CB 3.27Å; L172-F176 WeakPolarHBondContact O-CB 3.47Å; L172-F176 PolarHBondContact O-N 3.42Å; I173-F176 PolarHBondContact O-N 3.29Å; A174-F176 PolarHBondContact O-N 3.46Å; F176-L179 WeakPolarHBondContact O-CB 3.49Å; F176-L179 PolarHBondContact O-N 3.33Å
177	Y	74.4	Confident	80.4	Confident	9 Å²	9	28.3 Å²	28.3	4%	0.035	15%	0.15	C	C	.	.	H	α-helix	trans	-73.7	-31.8	-179	81.1	-97.6	0	0	0	112	I173 A174 I175 L179 V180 G181 M347 D351	I173-Y177 WeakPolarHBondContact O-CD1 3.5Å; I173-Y177 PolarHBondContact O-N 2.94Å; A174-Y177 VanDerWaalsContact CA-CE1 3.49Å; A174-Y177 HydrophobicContact CB-CE1 4.34Å; A174-Y177 WeakPolarHBondContact O-CD1 3.29Å; A174-Y177 WeakPolarHBondContact O-CE1 3.28Å; I175-Y177 PolarHBondContact O-N 2.82Å; Y177-L179 VanDerWaalsContact C-N 3.28Å; Y177-L179 PolarHBondContact O-N 3.42Å; Y177-V180 PolarHBondContact O-N 3.19Å; Y177-V180 VanDerWaalsContact O-N 3.16Å; Y177-G181 PolarHBondContact O-N 3.25Å; Y177-M347 HydrophobicContact CD1-CE 3.34Å; Y177-M347 HydrophobicContact CE1-CE 3.05Å; Y177-M347 HydrophobicContact CE1-CG 3.61Å; Y177-M347 HydrophobicContact CE1-SD 4.12Å; Y177-M347 HydrophobicContact CG-CE 4.29Å; Y177-M347 VanDerWaalsContact OH-CG 3.28Å; Y177-M347 WeakPolarHBondContact OH-CG 3.2Å; Y177-M347 PolarHBondContact OH-O 3.46Å; Y177-D351 HydrophobicContact CE2-CB 3.71Å; Y177-D351 WeakPolarHBondContact CE2-OD2 3.42Å; Y177-D351 WeakPolarHBondContact OH-CB 3.44Å; Y177-D351 PolarHBondContact OH-OD2 3.16Å; Y177-D351 VanDerWaalsContact OH-OD2 3.09Å
178	T	79.1	Confident	80.2	Confident	2 Å²	2	31 Å²	31	1%	0.012	16%	0.161	C	C	.	.	H	α-helix	trans	-60.2	-38.4	174.6	-53.6	0	0	0	0	111.4	A174 I175 V180 D351 L355 I387	A174-T178 WeakPolarHBondContact O-CB 3.49Å; A174-T178 PolarHBondContact O-N 3.25Å; A174-T178 PolarHBondContact O-OG1 3.1Å; I175-T178 PolarHBondContact O-N 3.18Å; T178-V180 VanDerWaalsContact C-N 3.27Å; T178-V180 PolarHBondContact O-N 3.12Å; T178-D351 HydrophobicContact CG2-CB 4.18Å; T178-D351 WeakPolarHBondContact OG1-CA 3.04Å; T178-D351 WeakPolarHBondContact OG1-CB 3.43Å; T178-L355 HydrophobicContact CG2-CB 4.27Å; T178-I387 HydrophobicContact CG2-CD1 4.19Å; T178-I387 HydrophobicContact CG2-CG1 4.46Å; T178-I387 HydrophobicContact CG2-CG2 4.08Å
179	L	79.6	Confident	80	Confident	44 Å²	44	28.2 Å²	28.2	23%	0.23	14%	0.144	C	C	.	.	H	α-helix	trans	-61.7	-32.2	177.2	-73.5	169	0	0	0	113.7	I175 F176 Y177 R384 I387	I175-L179 HydrophobicContact CG2-CD1 4.02Å; I175-L179 HydrophobicContact CG2-CG 4.36Å; I175-L179 VanDerWaalsContact O-CG 3.27Å; I175-L179 WeakPolarHBondContact O-CG 3.39Å; I175-L179 PolarHBondContact O-N 3.29Å; I175-L179 VanDerWaalsContact O-N 3.07Å; F176-L179 WeakPolarHBondContact O-CB 3.49Å; F176-L179 PolarHBondContact O-N 3.33Å; Y177-L179 VanDerWaalsContact C-N 3.28Å; Y177-L179 PolarHBondContact O-N 3.42Å; L179-R384 HydrophobicContact CD2-CB 3.96Å; L179-R384 HydrophobicContact CD2-CG 4.3Å; L179-R384 WeakPolarHBondContact CD2-O 3.36Å; L179-R384 PolarHBondContact O-NE 3.41Å; L179-I387 HydrophobicContact CD2-CB 3.81Å; L179-I387 HydrophobicContact CD2-CD1 4.4Å; L179-I387 HydrophobicContact CD2-CG2 3.63Å; L179-I387 HydrophobicContact CG-CG2 3.84Å
180	V	69.4	Low	80.2	Confident	62 Å²	62	25.3 Å²	25.3	38%	0.376	13%	0.129	S	C	.	.	H	α-helix	trans	-82	-34.8	-171.9	177	0	0	0	0	111.8	I23 Y177 T178	I23-V180 HydrophobicContact CG1-CG1 4.41Å; Y177-V180 PolarHBondContact O-N 3.19Å; Y177-V180 VanDerWaalsContact O-N 3.16Å; T178-V180 VanDerWaalsContact C-N 3.27Å; T178-V180 PolarHBondContact O-N 3.12Å
181	G	65.6	Low	80.5	Confident	11 Å²	11	26 Å²	26	11%	0.113	13%	0.133	C	C	.	.	H	α-helix	trans	-111.7	-25.1	-153.5	0	0	0	0	0	119.1	Y177 S185	Y177-G181 PolarHBondContact O-N 3.25Å; G181-S185 VanDerWaalsContact O-CB 3.29Å; G181-S185 WeakPolarHBondContact O-CB 3.08Å; G181-S185 PolarHBondContact O-N 2.89Å
182	G	75.2	Confident	80.5	Confident	8 Å²	8	27.9 Å²	27.9	8%	0.082	14%	0.144	C	C	.	.	H	α-helix	trans	60.7	-169.6	-174.2	0	0	0	0	0	113.8	Y184 S185 V186	G182-Y184 VanDerWaalsContact C-N 3.29Å; G182-Y184 PolarHBondContact O-N 3.22Å; G182-S185 PolarHBondContact O-N 2.72Å; G182-V186 WeakPolarHBondContact O-CG2 3.35Å; G182-V186 PolarHBondContact O-N 2.82Å
183	L	78.1	Confident	80.6	Confident	1 Å²	1	22.9 Å²	22.9	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-59.2	-35.6	-172.8	-173.7	66.6	0	0	0	113.6	I44 I51 V186 A187 Q261 L355	I44-L183 WeakPolarHBondContact O-CB 3.44Å; I44-L183 PolarHBondContact O-N 2.76Å; I51-L183 HydrophobicContact CD1-CD2 4.2Å; I51-L183 HydrophobicContact CD1-CG 4.46Å; L183-V186 PolarHBondContact O-N 3.3Å; L183-A187 VanDerWaalsContact O-CB 3.32Å; L183-A187 WeakPolarHBondContact O-CB 3.16Å; L183-A187 PolarHBondContact O-N 2.98Å; L183-Q261 HydrophobicContact CD1-CG 4Å; L183-Q261 HydrophobicContact CD2-CG 4.12Å; L183-L355 HydrophobicContact CB-CD2 4.19Å; L183-L355 HydrophobicContact CD1-CD2 4.23Å
184	Y	77.8	Confident	81	Confident	35 Å²	35	20.8 Å²	20.8	14%	0.137	11%	0.107	C	C	.	.	H	α-helix	trans	-64.5	-46	178.4	-96.3	-68.1	0	0	0	112.5	G47 I51 G182 V186 A187 Y188	G47-Y184 VanDerWaalsContact CA-CE2 3.48Å; G47-Y184 WeakPolarHBondContact O-CE2 3.43Å; G47-Y184 VanDerWaalsContact O-CZ 3.22Å; G47-Y184 PolarHBondContact O-OH 3.29Å; I51-Y184 HydrophobicContact CG1-CE1 4.32Å; G182-Y184 VanDerWaalsContact C-N 3.29Å; G182-Y184 PolarHBondContact O-N 3.22Å; Y184-V186 VanDerWaalsContact C-N 3.31Å; Y184-V186 PolarHBondContact O-N 3.24Å; Y184-A187 PolarHBondContact O-N 3.02Å; Y184-Y188 HydrophobicContact CD1-CD2 4.38Å; Y184-Y188 AromaticContact CD1-CE2 3.96Å; Y184-Y188 HydrophobicContact CD1-CE2 3.96Å; Y184-Y188 HydrophobicContact CE1-CE2 4.49Å; Y184-Y188 VanDerWaalsContact O-CD2 3.31Å; Y184-Y188 WeakPolarHBondContact O-CD2 3.38Å; Y184-Y188 PolarHBondContact O-N 3Å; Y184-Y188 VanDerWaalsContact O-N 3.09Å
185	S	78	Confident	81.5	Confident	2 Å²	2	25 Å²	25	1%	0.014	13%	0.125	C	C	.	.	H	α-helix	trans	-59.9	-46.6	176.7	177.7	0	0	0	0	111	G22 G181 G182 A187 Y188 T189	G22-S185 WeakPolarHBondContact CA-OG 3.25Å; G22-S185 PolarHBondContact O-OG 2.91Å; G181-S185 VanDerWaalsContact O-CB 3.29Å; G181-S185 WeakPolarHBondContact O-CB 3.08Å; G181-S185 PolarHBondContact O-N 2.89Å; G182-S185 PolarHBondContact O-N 2.72Å; S185-A187 VanDerWaalsContact C-N 3.35Å; S185-A187 PolarHBondContact O-N 2.73Å; S185-Y188 PolarHBondContact O-N 3.22Å; S185-T189 WeakPolarHBondContact O-CG2 3.45Å; S185-T189 PolarHBondContact O-N 3.42Å; S185-T189 PolarHBondContact O-OG1 3.43Å
186	V	81.9	Confident	81.7	Confident	1 Å²	1	25.6 Å²	25.6	1%	0.006	13%	0.13	C	C	.	.	H	α-helix	trans	-57	-48.3	177	171	0	0	0	0	110.4	G182 L183 Y184 Y188 T189 D190 D351 L355	G182-V186 WeakPolarHBondContact O-CG2 3.35Å; G182-V186 PolarHBondContact O-N 2.82Å; L183-V186 PolarHBondContact O-N 3.3Å; Y184-V186 VanDerWaalsContact C-N 3.31Å; Y184-V186 PolarHBondContact O-N 3.24Å; V186-Y188 VanDerWaalsContact C-N 3.35Å; V186-Y188 PolarHBondContact O-N 3.08Å; V186-T189 WeakPolarHBondContact CA-OG1 3.43Å; V186-T189 PolarHBondContact O-N 2.74Å; V186-T189 PolarHBondContact O-OG1 3.39Å; V186-D190 WeakPolarHBondContact O-CB 3.41Å; V186-D190 PolarHBondContact O-N 2.85Å; V186-D351 WeakPolarHBondContact CG1-OD2 3.39Å; V186-D351 HydrophobicContact CG2-CB 4.19Å; V186-D351 WeakPolarHBondContact CG2-OD2 3.49Å; V186-L355 HydrophobicContact CG2-CD2 4.04Å
187	A	83.6	Confident	82	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-63.7	-36	-178.2	0	0	0	0	0	113.6	I51 V55 T59 L183 Y184 S185 V191	I51-A187 HydrophobicContact CD1-CB 4.23Å; V55-A187 HydrophobicContact CG1-CB 3.89Å; T59-A187 HydrophobicContact CG2-CB 4.24Å; L183-A187 VanDerWaalsContact O-CB 3.32Å; L183-A187 WeakPolarHBondContact O-CB 3.16Å; L183-A187 PolarHBondContact O-N 2.98Å; Y184-A187 PolarHBondContact O-N 3.02Å; S185-A187 VanDerWaalsContact C-N 3.35Å; S185-A187 PolarHBondContact O-N 2.73Å; A187-V191 VanDerWaalsContact O-CG2 3.32Å; A187-V191 WeakPolarHBondContact O-CG2 3.43Å; A187-V191 PolarHBondContact O-N 3.19Å
188	Y	83.6	Confident	82.8	Confident	60 Å²	60	23.2 Å²	23.2	24%	0.235	12%	0.12	C	C	.	.	H	α-helix	trans	-77.1	-36.2	176.9	-84.3	-85.6	0	0	0	112.6	W24 A25 V55 Y184 S185 V186 D190 V191 V192	W24-Y188 HydrophobicContact CZ3-CD1 4.23Å; W24-Y188 HydrophobicContact CZ3-CE1 4.38Å; A25-Y188 HydrophobicContact CB-CD2 3.94Å; A25-Y188 HydrophobicContact CB-CG 4.01Å; V55-Y188 HydrophobicContact CG2-CE1 4.4Å; Y184-Y188 HydrophobicContact CD1-CD2 4.38Å; Y184-Y188 AromaticContact CD1-CE2 3.96Å; Y184-Y188 HydrophobicContact CD1-CE2 3.96Å; Y184-Y188 HydrophobicContact CE1-CE2 4.49Å; Y184-Y188 VanDerWaalsContact O-CD2 3.31Å; Y184-Y188 WeakPolarHBondContact O-CD2 3.38Å; Y184-Y188 PolarHBondContact O-N 3Å; Y184-Y188 VanDerWaalsContact O-N 3.09Å; S185-Y188 PolarHBondContact O-N 3.22Å; V186-Y188 VanDerWaalsContact C-N 3.35Å; V186-Y188 PolarHBondContact O-N 3.08Å; Y188-D190 VanDerWaalsContact C-N 3.33Å; Y188-V191 PolarHBondContact O-N 3.44Å; Y188-V192 PolarHBondContact O-N 3.22Å
189	T	85.9	Confident	83.5	Confident	0 Å²	0	27.1 Å²	27.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-64.7	-41.4	172.6	48.6	0	0	0	0	110.7	I18 V21 S185 V186 V191 V192 Q193	I18-T189 HydrophobicContact CG2-CG2 3.89Å; V21-T189 HydrophobicContact CB-CG2 4.39Å; V21-T189 HydrophobicContact CG1-CG2 4.15Å; S185-T189 WeakPolarHBondContact O-CG2 3.45Å; S185-T189 PolarHBondContact O-N 3.42Å; S185-T189 PolarHBondContact O-OG1 3.43Å; V186-T189 WeakPolarHBondContact CA-OG1 3.43Å; V186-T189 PolarHBondContact O-N 2.74Å; V186-T189 PolarHBondContact O-OG1 3.39Å; T189-V191 VanDerWaalsContact C-N 3.28Å; T189-V191 PolarHBondContact O-N 3.3Å; T189-V192 PolarHBondContact O-N 2.85Å; T189-V192 VanDerWaalsContact O-N 3.12Å; T189-Q193 WeakPolarHBondContact O-CB 3.28Å; T189-Q193 VanDerWaalsContact O-CG 3.27Å; T189-Q193 WeakPolarHBondContact O-CG 3.23Å; T189-Q193 PolarHBondContact O-N 3.28Å; T189-Q193 PolarHBondContact O-OE1 3.01Å; T189-Q193 VanDerWaalsContact O-OE1 3.09Å
190	D	88.3	Confident	84	Confident	0 Å²	0	25 Å²	25	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-55.6	-41.9	177.1	-75.9	-9.3	0	0	0	112.3	T59 A62 V186 Y188 Q193 L194 R262 S348	T59-D190 WeakPolarHBondContact CB-OD2 3.19Å; T59-D190 PolarHBondContact OG1-OD2 3.19Å; A62-D190 HydrophobicContact CB-CB 3.78Å; V186-D190 WeakPolarHBondContact O-CB 3.41Å; V186-D190 PolarHBondContact O-N 2.85Å; Y188-D190 VanDerWaalsContact C-N 3.33Å; D190-Q193 PolarHBondContact O-N 3.13Å; D190-L194 VanDerWaalsContact O-CB 3.31Å; D190-L194 WeakPolarHBondContact O-CB 3.26Å; D190-L194 PolarHBondContact O-N 3.17Å; D190-R262 IonicContact OD2-NH2 3.69Å; D190-R262 PolarHBondContact OD2-NH2 3.47Å; D190-S348 VanDerWaalsContact OD1-CB 3.26Å; D190-S348 WeakPolarHBondContact OD1-CB 3.31Å
191	V	87.6	Confident	85.1	Confident	15 Å²	15	22 Å²	22	9%	0.091	11%	0.111	C	C	.	.	H	α-helix	trans	-59.9	-51.7	177.9	173	0	0	0	0	110.1	F54 V55 F58 A187 Y188 T189 L194 F195	F54-V191 HydrophobicContact CE1-CG1 4.09Å; V55-V191 HydrophobicContact CG1-CG2 4.2Å; F58-V191 HydrophobicContact CB-CB 4.34Å; F58-V191 HydrophobicContact CB-CG2 3.7Å; F58-V191 HydrophobicContact CD1-CG1 4.46Å; F58-V191 HydrophobicContact CG-CG1 4.5Å; F58-V191 HydrophobicContact CG-CG2 4.46Å; A187-V191 VanDerWaalsContact O-CG2 3.32Å; A187-V191 WeakPolarHBondContact O-CG2 3.43Å; A187-V191 PolarHBondContact O-N 3.19Å; Y188-V191 PolarHBondContact O-N 3.44Å; T189-V191 VanDerWaalsContact C-N 3.28Å; T189-V191 PolarHBondContact O-N 3.3Å; V191-L194 PolarHBondContact O-N 2.94Å; V191-F195 HydrophobicContact CG1-CD2 3.97Å; V191-F195 HydrophobicContact CG1-CE2 3.83Å; V191-F195 WeakPolarHBondContact O-CD2 3.26Å; V191-F195 PolarHBondContact O-N 3.11Å; V191-F195 VanDerWaalsContact O-N 3.15Å
192	V	87.8	Confident	86.5	Confident	41 Å²	41	25.8 Å²	25.8	25%	0.248	12%	0.122	C	C	.	.	H	α-helix	trans	-63.6	-43.9	-179.2	177.1	0	0	0	0	110.6	L17 I18 V21 Y188 T189 F195 C196	L17-V192 HydrophobicContact CD2-CG1 3.77Å; I18-V192 HydrophobicContact CD1-CG1 4.14Å; V21-V192 HydrophobicContact CG1-CG2 4.13Å; V21-V192 HydrophobicContact CG2-CG2 4.33Å; Y188-V192 PolarHBondContact O-N 3.22Å; T189-V192 PolarHBondContact O-N 2.85Å; T189-V192 VanDerWaalsContact O-N 3.12Å; V192-F195 PolarHBondContact O-N 3.02Å; V192-C196 PolarHBondContact O-N 3.03Å; V192-C196 PolarHBondContact O-SG 3.25Å; V192-C196 VanDerWaalsContact O-SG 3.33Å
193	Q	88.5	Confident	87.4	Confident	0 Å²	0	28.6 Å²	28.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-61.5	-45.8	178.3	-71.2	163.3	-50.8	0	0	110.8	F14 I18 T189 D190 F195 C196 I197 A344 S348	F14-Q193 HydrophobicContact CZ-CG 4.39Å; I18-Q193 HydrophobicContact CD1-CG 3.54Å; I18-Q193 HydrophobicContact CG1-CG 4.28Å; T189-Q193 WeakPolarHBondContact O-CB 3.28Å; T189-Q193 VanDerWaalsContact O-CG 3.27Å; T189-Q193 WeakPolarHBondContact O-CG 3.23Å; T189-Q193 PolarHBondContact O-N 3.28Å; T189-Q193 PolarHBondContact O-OE1 3.01Å; T189-Q193 VanDerWaalsContact O-OE1 3.09Å; D190-Q193 PolarHBondContact O-N 3.13Å; Q193-F195 VanDerWaalsContact C-N 3.34Å; Q193-F195 PolarHBondContact O-N 2.66Å; Q193-C196 CarbonylContact O-C 3.6Å; Q193-C196 WeakPolarHBondContact O-CB 3.4Å; Q193-C196 PolarHBondContact O-N 2.82Å; Q193-C196 VanDerWaalsContact O-N 3.08Å; Q193-I197 WeakPolarHBondContact O-CD1 3.42Å; Q193-I197 WeakPolarHBondContact O-CG1 3.47Å; Q193-I197 PolarHBondContact O-N 3.16Å; Q193-A344 HydrophobicContact CB-CB 4.05Å; Q193-A344 HydrophobicContact CG-CB 4.05Å; Q193-A344 PolarHBondContact NE2-O 3.09Å; Q193-S348 VanDerWaalsContact OE1-CB 3.28Å
194	L	89.5	Confident	88.1	Confident	11 Å²	11	28.5 Å²	28.5	6%	0.058	13%	0.134	C	C	.	.	H	α-helix	trans	-61.4	-39.9	178.5	-164.6	69.3	0	0	0	112.9	F58 T61 A62 V65 D190 V191 I197 F198 M286	F58-L194 HydrophobicContact CB-CD2 4.28Å; F58-L194 HydrophobicContact CD1-CB 4.28Å; F58-L194 HydrophobicContact CD1-CD2 3.6Å; F58-L194 HydrophobicContact CD1-CG 4.36Å; F58-L194 HydrophobicContact CE1-CD2 4.27Å; F58-L194 HydrophobicContact CG-CD2 4.23Å; T61-L194 HydrophobicContact CG2-CD1 4.19Å; T61-L194 HydrophobicContact CG2-CD2 3.85Å; A62-L194 HydrophobicContact CB-CB 4.2Å; A62-L194 HydrophobicContact CB-CD1 4.2Å; V65-L194 HydrophobicContact CB-CD1 4.31Å; V65-L194 HydrophobicContact CG1-CD1 4.3Å; D190-L194 VanDerWaalsContact O-CB 3.31Å; D190-L194 WeakPolarHBondContact O-CB 3.26Å; D190-L194 PolarHBondContact O-N 3.17Å; V191-L194 PolarHBondContact O-N 2.94Å; L194-I197 HydrophobicContact CD1-CD1 4.42Å; L194-I197 PolarHBondContact O-N 2.83Å; L194-F198 WeakPolarHBondContact O-CB 3.29Å; L194-F198 PolarHBondContact O-N 2.97Å; L194-M286 HydrophobicContact CD1-CE 3.85Å; L194-M286 HydrophobicContact CD1-CG 4.27Å; L194-M286 HydrophobicContact CD1-SD 4.31Å
195	F	89.8	Confident	89	Confident	89 Å²	89	27.3 Å²	27.3	39%	0.39	13%	0.13	S	C	.	.	H	α-helix	trans	-62.1	-43.4	172.7	-84	-69.7	0	0	0	112.1	F54 F58 V191 V192 Q193 F198 L199	F54-F195 HydrophobicContact CZ-CE2 4.05Å; F54-F195 HydrophobicContact CZ-CZ 4.09Å; F58-F195 HydrophobicContact CD1-CD2 4.34Å; F58-F195 AromaticContact CD1-CE2 3.93Å; F58-F195 HydrophobicContact CD1-CE2 3.93Å; F58-F195 HydrophobicContact CD1-CZ 4.34Å; F58-F195 HydrophobicContact CE1-CD2 4.03Å; F58-F195 AromaticContact CE1-CE1 3.98Å; F58-F195 HydrophobicContact CE1-CE1 3.98Å; F58-F195 AromaticContact CE1-CE2 3.42Å; F58-F195 HydrophobicContact CE1-CE2 3.42Å; F58-F195 VanDerWaalsContact CE1-CE2 3.42Å; F58-F195 AromaticContact CE1-CZ 3.4Å; F58-F195 HydrophobicContact CE1-CZ 3.4Å; F58-F195 HydrophobicContact CZ-CE1 4.23Å; F58-F195 AromaticContact CZ-CE2 3.87Å; F58-F195 HydrophobicContact CZ-CE2 3.87Å; F58-F195 AromaticContact CZ-CZ 3.5Å; F58-F195 HydrophobicContact CZ-CZ 3.5Å; V191-F195 HydrophobicContact CG1-CD2 3.97Å; V191-F195 HydrophobicContact CG1-CE2 3.83Å; V191-F195 WeakPolarHBondContact O-CD2 3.26Å; V191-F195 PolarHBondContact O-N 3.11Å; V191-F195 VanDerWaalsContact O-N 3.15Å; V192-F195 PolarHBondContact O-N 3.02Å; Q193-F195 VanDerWaalsContact C-N 3.34Å; Q193-F195 PolarHBondContact O-N 2.66Å; F195-F198 PolarHBondContact O-N 2.98Å; F195-L199 WeakPolarHBondContact O-CG 3.19Å; F195-L199 PolarHBondContact O-N 3.04Å
196	C	89.1	Confident	89.8	Confident	24 Å²	24	30.6 Å²	30.6	16%	0.162	15%	0.152	C	C	.	.	H	α-helix	trans	-62.8	-42.8	176	-68.6	0	0	0	0	111.9	F14 V192 Q193 G200 A341	F14-C196 HydrophobicContact CE2-CB 4.15Å; V192-C196 PolarHBondContact O-N 3.03Å; V192-C196 PolarHBondContact O-SG 3.25Å; V192-C196 VanDerWaalsContact O-SG 3.33Å; Q193-C196 CarbonylContact O-C 3.6Å; Q193-C196 WeakPolarHBondContact O-CB 3.4Å; Q193-C196 PolarHBondContact O-N 2.82Å; Q193-C196 VanDerWaalsContact O-N 3.08Å; C196-G200 WeakPolarHBondContact O-CA 3.23Å; C196-G200 PolarHBondContact O-N 3.02Å; C196-A341 VanDerWaalsContact O-CB 3.3Å; C196-A341 WeakPolarHBondContact O-CB 3.34Å
197	I	89.9	Confident	90.3	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-60	-48.8	175.4	-59.5	158.9	0	0	0	110.4	I70 Q193 L194 G200 L201 M286 A341 A344 A345	I70-I197 HydrophobicContact CD1-CG2 3.68Å; Q193-I197 WeakPolarHBondContact O-CD1 3.42Å; Q193-I197 WeakPolarHBondContact O-CG1 3.47Å; Q193-I197 PolarHBondContact O-N 3.16Å; L194-I197 HydrophobicContact CD1-CD1 4.42Å; L194-I197 PolarHBondContact O-N 2.83Å; I197-G200 PolarHBondContact O-N 3.2Å; I197-L201 HydrophobicContact CG2-CD1 3.78Å; I197-L201 HydrophobicContact CG2-CG 4.33Å; I197-L201 WeakPolarHBondContact O-CB 3.39Å; I197-L201 WeakPolarHBondContact O-CG 3.36Å; I197-L201 PolarHBondContact O-N 3.19Å; I197-M286 HydrophobicContact CB-CE 3.7Å; I197-M286 HydrophobicContact CG2-CE 3.27Å; I197-A341 VanDerWaalsContact CG1-O 3.3Å; I197-A341 WeakPolarHBondContact CG1-O 3.16Å; I197-A344 HydrophobicContact CG1-CB 4.21Å; I197-A345 HydrophobicContact CD1-CB 3.33Å; I197-A345 HydrophobicContact CG1-CB 3.76Å
198	F	91.4	Very high	90.8	Very high	81 Å²	81	34.4 Å²	34.4	36%	0.355	17%	0.168	S	C	.	.	H	α-helix	trans	-60.1	-55.4	-178.1	-178.9	-95.2	0	0	0	110.1	L194 F195 G200 W202 V285 M286	L194-F198 WeakPolarHBondContact O-CB 3.29Å; L194-F198 PolarHBondContact O-N 2.97Å; F195-F198 PolarHBondContact O-N 2.98Å; F198-G200 PolarHBondContact O-N 3.17Å; F198-W202 AromaticContact CD2-CD1 3.57Å; F198-W202 AromaticContact CD2-NE1 3.64Å; F198-W202 AromaticContact CE2-CD1 3.6Å; F198-W202 HydrophobicContact CE2-CG 4.49Å; F198-W202 AromaticContact CE2-NE1 3.42Å; F198-W202 VanDerWaalsContact O-CB 3.25Å; F198-W202 WeakPolarHBondContact O-CB 3.39Å; F198-W202 PolarHBondContact O-N 3.05Å; F198-W202 VanDerWaalsContact O-N 3.13Å; F198-V285 HydrophobicContact CE2-CG1 4.03Å; F198-M286 HydrophobicContact CB-CE 4.09Å; F198-M286 HydrophobicContact CB-SD 3.9Å; F198-M286 HydrophobicContact CD2-SD 3.62Å; F198-M286 HydrophobicContact CG-SD 4.25Å
199	L	92.4	Very high	91.3	Very high	84 Å²	84	34.7 Å²	34.7	44%	0.44	17%	0.173	S	C	.	.	H	α-helix	trans	-64.9	-43.6	-179.8	-65.4	176.7	0	0	0	111.9	F195 I203 F337	F195-L199 WeakPolarHBondContact O-CG 3.19Å; F195-L199 PolarHBondContact O-N 3.04Å; L199-I203 HydrophobicContact CB-CD1 4.3Å; L199-I203 WeakPolarHBondContact O-CB 3.36Å; L199-I203 WeakPolarHBondContact O-CD1 3.07Å; L199-I203 WeakPolarHBondContact O-CG1 3.08Å; L199-I203 PolarHBondContact O-N 3.28Å; L199-F337 HydrophobicContact CB-CE1 4.07Å; L199-F337 HydrophobicContact CB-CZ 4.26Å
200	G	91.4	Very high	91.6	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-58.5	-55.7	-176.9	0	0	0	0	0	112	C196 I197 F198 S204 F337	C196-G200 WeakPolarHBondContact O-CA 3.23Å; C196-G200 PolarHBondContact O-N 3.02Å; I197-G200 PolarHBondContact O-N 3.2Å; F198-G200 PolarHBondContact O-N 3.17Å; G200-S204 PolarHBondContact O-N 3Å; G200-S204 VanDerWaalsContact O-N 3.07Å; G200-S204 PolarHBondContact O-OG 2.8Å; G200-F337 VanDerWaalsContact CA-CE1 3.44Å
201	L	92	Very high	91.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-72.2	-41.9	-176.1	-60.2	-179.3	0	0	0	112.3	I70 I197 I203 S204 V205 P289 I293 L322 L326 V342	I70-L201 HydrophobicContact CD1-CD1 4.09Å; I70-L201 HydrophobicContact CG2-CD1 3.84Å; I197-L201 HydrophobicContact CG2-CD1 3.78Å; I197-L201 HydrophobicContact CG2-CG 4.33Å; I197-L201 WeakPolarHBondContact O-CB 3.39Å; I197-L201 WeakPolarHBondContact O-CG 3.36Å; I197-L201 PolarHBondContact O-N 3.19Å; L201-I203 VanDerWaalsContact C-N 3.33Å; L201-I203 PolarHBondContact O-N 3.41Å; L201-S204 PolarHBondContact O-N 2.92Å; L201-V205 WeakPolarHBondContact O-CG2 3.43Å; L201-V205 PolarHBondContact O-N 3.11Å; L201-V205 VanDerWaalsContact O-N 3.16Å; L201-P289 HydrophobicContact CB-CB 3.78Å; L201-P289 HydrophobicContact CB-CG 3.93Å; L201-P289 HydrophobicContact CD1-CG 4.41Å; L201-I293 HydrophobicContact CD2-CD1 4.1Å; L201-L322 HydrophobicContact CD2-CD2 4.39Å; L201-L326 HydrophobicContact CD2-CD1 4.36Å; L201-V342 HydrophobicContact CD2-CG2 3.98Å
202	W	94.6	Very high	91.9	Very high	89 Å²	89	45.8 Å²	45.8	34%	0.337	25%	0.246	S	C	.	.	H	α-helix	trans	-66.2	-34.4	179.3	-81.4	97.7	0	0	0	113	F198 P206 V288	F198-W202 AromaticContact CD2-CD1 3.57Å; F198-W202 AromaticContact CD2-NE1 3.64Å; F198-W202 AromaticContact CE2-CD1 3.6Å; F198-W202 HydrophobicContact CE2-CG 4.49Å; F198-W202 AromaticContact CE2-NE1 3.42Å; F198-W202 VanDerWaalsContact O-CB 3.25Å; F198-W202 WeakPolarHBondContact O-CB 3.39Å; F198-W202 PolarHBondContact O-N 3.05Å; F198-W202 VanDerWaalsContact O-N 3.13Å; W202-P206 WeakPolarHBondContact O-CD 3.34Å; W202-V288 HydrophobicContact CH2-CB 4.1Å; W202-V288 HydrophobicContact CH2-CG1 3.63Å; W202-V288 HydrophobicContact CZ2-CB 3.9Å; W202-V288 HydrophobicContact CZ2-CG1 3.97Å; W202-V288 HydrophobicContact CZ3-CG1 4.47Å
203	I	94.1	Very high	92	Very high	67 Å²	67	44 Å²	44	34%	0.344	24%	0.235	S	C	.	.	H	α-helix	trans	-71.2	-38.1	173.7	-67.7	169	0	0	0	110.2	L199 L201 V205 P206 F207 I334 F337	L199-I203 HydrophobicContact CB-CD1 4.3Å; L199-I203 WeakPolarHBondContact O-CB 3.36Å; L199-I203 WeakPolarHBondContact O-CD1 3.07Å; L199-I203 WeakPolarHBondContact O-CG1 3.08Å; L199-I203 PolarHBondContact O-N 3.28Å; L201-I203 VanDerWaalsContact C-N 3.33Å; L201-I203 PolarHBondContact O-N 3.41Å; I203-V205 PolarHBondContact O-N 2.89Å; I203-P206 WeakPolarHBondContact O-CD 3.4Å; I203-P206 VanDerWaalsContact O-CG 3.29Å; I203-P206 WeakPolarHBondContact O-CG 3.33Å; I203-F207 HydrophobicContact CG2-CD2 4.29Å; I203-F207 HydrophobicContact CG2-CE2 4.05Å; I203-F207 VanDerWaalsContact O-CD2 3.27Å; I203-F207 WeakPolarHBondContact O-CD2 3.32Å; I203-I334 HydrophobicContact CG2-CD1 3.87Å; I203-I334 HydrophobicContact CG2-CG2 4.32Å; I203-F337 HydrophobicContact CD1-CE1 4.41Å
204	S	93.7	Very high	92.2	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-65.1	-35.3	-179.8	-62	0	0	0	0	114.2	G200 L201 F207 A208 L326	G200-S204 PolarHBondContact O-N 3Å; G200-S204 VanDerWaalsContact O-N 3.07Å; G200-S204 PolarHBondContact O-OG 2.8Å; L201-S204 PolarHBondContact O-N 2.92Å; S204-F207 PolarHBondContact O-N 3.39Å; S204-A208 WeakPolarHBondContact O-CB 3.22Å; S204-A208 PolarHBondContact O-N 3.43Å; S204-L326 WeakPolarHBondContact OG-CD2 3.31Å
205	V	95.4	Very high	92.3	Very high	9 Å²	9	45.5 Å²	45.5	6%	0.055	25%	0.247	C	C	.	.	H	α-helix	trans	-52.8	-55.5	-177.8	167.7	0	0	0	0	114.1	L201 I203 F207 A208 L209 P289 L292 I293	L201-V205 WeakPolarHBondContact O-CG2 3.43Å; L201-V205 PolarHBondContact O-N 3.11Å; L201-V205 VanDerWaalsContact O-N 3.16Å; I203-V205 PolarHBondContact O-N 2.89Å; V205-F207 VanDerWaalsContact C-N 3.32Å; V205-F207 PolarHBondContact O-N 3.42Å; V205-A208 PolarHBondContact O-N 3.17Å; V205-L209 HydrophobicContact CG1-CD1 3.83Å; V205-L209 HydrophobicContact CG1-CG 4.49Å; V205-L209 WeakPolarHBondContact O-CG 3.3Å; V205-L209 PolarHBondContact O-N 2.75Å; V205-P289 HydrophobicContact CG2-CB 3.9Å; V205-L292 HydrophobicContact CG1-CB 4.17Å; V205-L292 HydrophobicContact CG1-CD1 3.81Å; V205-L292 HydrophobicContact CG2-CB 4.17Å; V205-L292 HydrophobicContact CG2-CD1 4.46Å; V205-I293 HydrophobicContact CG2-CD1 4.49Å; V205-I293 HydrophobicContact CG2-CG1 4.16Å
206	P	94.8	Very high	92.5	Very high	71 Å²	71	46.3 Å²	46.3	46%	0.461	26%	0.256	S	S	.	.	H	α-helix	trans	-63.5	-35.3	-178.8	23.3	-34.8	0	0	0	113	W202 I203 L209 S210	W202-P206 WeakPolarHBondContact O-CD 3.34Å; I203-P206 WeakPolarHBondContact O-CD 3.4Å; I203-P206 VanDerWaalsContact O-CG 3.29Å; I203-P206 WeakPolarHBondContact O-CG 3.33Å; P206-L209 PolarHBondContact O-N 3.02Å; P206-S210 WeakPolarHBondContact O-CB 3.15Å; P206-S210 PolarHBondContact O-N 3.45Å; P206-S210 PolarHBondContact O-OG 2.97Å
207	F	93.9	Very high	92.6	Very high	82 Å²	82	46.6 Å²	46.6	36%	0.36	26%	0.255	S	S	.	.	H	α-helix	trans	-67.4	-44.6	176.1	-75.8	-77.9	0	0	0	111.6	I203 S204 V205 L209 S210 N211 P331 I334	I203-F207 HydrophobicContact CG2-CD2 4.29Å; I203-F207 HydrophobicContact CG2-CE2 4.05Å; I203-F207 VanDerWaalsContact O-CD2 3.27Å; I203-F207 WeakPolarHBondContact O-CD2 3.32Å; S204-F207 PolarHBondContact O-N 3.39Å; V205-F207 VanDerWaalsContact C-N 3.32Å; V205-F207 PolarHBondContact O-N 3.42Å; F207-L209 VanDerWaalsContact C-N 3.34Å; F207-L209 PolarHBondContact O-N 3.26Å; F207-S210 PolarHBondContact O-N 3.43Å; F207-S210 PolarHBondContact O-OG 3.33Å; F207-N211 PolarHBondContact O-N 3.02Å; F207-P331 HydrophobicContact CD1-CG 3.82Å; F207-P331 HydrophobicContact CE1-CG 4.37Å; F207-P331 HydrophobicContact CG-CG 4.43Å; F207-I334 HydrophobicContact CB-CG2 4.5Å; F207-I334 HydrophobicContact CD2-CB 4.49Å; F207-I334 HydrophobicContact CD2-CD1 4.3Å; F207-I334 HydrophobicContact CD2-CG1 3.87Å; F207-I334 HydrophobicContact CD2-CG2 4Å; F207-I334 HydrophobicContact CE2-CD1 3.94Å; F207-I334 HydrophobicContact CE2-CG1 3.89Å; F207-I334 HydrophobicContact CG-CG1 4.26Å; F207-I334 HydrophobicContact CG-CG2 4.45Å; F207-I334 HydrophobicContact CZ-CD1 4.43Å; F207-I334 HydrophobicContact CZ-CG1 4.27Å
208	A	93.8	Very high	92.6	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-62.2	-41.2	176.1	0	0	0	0	0	111.7	S204 V205 S210 N211 V214 I296 V325 L329	S204-A208 WeakPolarHBondContact O-CB 3.22Å; S204-A208 PolarHBondContact O-N 3.43Å; V205-A208 PolarHBondContact O-N 3.17Å; A208-S210 VanDerWaalsContact C-N 3.32Å; A208-S210 PolarHBondContact O-N 3.04Å; A208-N211 VanDerWaalsContact O-CB 3.3Å; A208-N211 WeakPolarHBondContact O-CB 3.3Å; A208-N211 PolarHBondContact O-N 2.89Å; A208-V214 WeakPolarHBondContact O-CG2 3.06Å; A208-I296 HydrophobicContact CB-CD1 3.83Å; A208-I296 HydrophobicContact CB-CG2 4.25Å; A208-V325 HydrophobicContact CB-CG1 4.2Å; A208-L329 HydrophobicContact CB-CB 4.38Å
209	L	93.8	Very high	92.5	Very high	65 Å²	65	47.8 Å²	47.8	34%	0.34	28%	0.278	S	S	.	.	H	α-helix	trans	-65	-32.2	175.1	-75.5	169.3	0	0	0	113.6	V205 P206 F207 N211 I217 I296	V205-L209 HydrophobicContact CG1-CD1 3.83Å; V205-L209 HydrophobicContact CG1-CG 4.49Å; V205-L209 WeakPolarHBondContact O-CG 3.3Å; V205-L209 PolarHBondContact O-N 2.75Å; P206-L209 PolarHBondContact O-N 3.02Å; F207-L209 VanDerWaalsContact C-N 3.34Å; F207-L209 PolarHBondContact O-N 3.26Å; L209-N211 PolarHBondContact O-N 2.67Å; L209-I217 HydrophobicContact CD2-CD1 3.86Å; L209-I217 HydrophobicContact CD2-CG1 4.02Å; L209-I217 HydrophobicContact CD2-CG2 3.69Å; L209-I296 HydrophobicContact CD2-CD1 3.87Å; L209-I296 HydrophobicContact CD2-CG1 3.6Å; L209-I296 HydrophobicContact CG-CD1 3.72Å; L209-I296 HydrophobicContact CG-CG1 4.05Å
210	S	92.3	Very high	92.4	Very high	86 Å²	86	44 Å²	44	60%	0.601	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.3	-7.2	179.4	71.6	0	0	0	0	113.9	P206 F207 A208	P206-S210 WeakPolarHBondContact O-CB 3.15Å; P206-S210 PolarHBondContact O-N 3.45Å; P206-S210 PolarHBondContact O-OG 2.97Å; F207-S210 PolarHBondContact O-N 3.43Å; F207-S210 PolarHBondContact O-OG 3.33Å; A208-S210 VanDerWaalsContact C-N 3.32Å; A208-S210 PolarHBondContact O-N 3.04Å
211	N	92.3	Very high	92.4	Very high	38 Å²	38	44.4 Å²	44.4	20%	0.203	26%	0.262	C	S	.	.	S	Bend	trans	-69.4	130.1	-177.7	-169.5	-60.8	0	0	0	110.8	F207 A208 L209 A213 V214 L329	F207-N211 PolarHBondContact O-N 3.02Å; A208-N211 VanDerWaalsContact O-CB 3.3Å; A208-N211 WeakPolarHBondContact O-CB 3.3Å; A208-N211 PolarHBondContact O-N 2.89Å; L209-N211 PolarHBondContact O-N 2.67Å; N211-A213 PolarHBondContact O-N 3.45Å; N211-A213 WeakPolarHBondContact OD1-CB 3.18Å; N211-A213 PolarHBondContact OD1-N 2.79Å; N211-V214 HydrophobicContact CB-CG2 4Å; N211-V214 WeakPolarHBondContact O-CB 3.13Å; N211-V214 PolarHBondContact O-N 2.95Å; N211-L329 HydrophobicContact CB-CB 4.42Å; N211-L329 WeakPolarHBondContact ND2-CA 3.27Å; N211-L329 PolarHBondContact ND2-O 3.37Å
212	P	90.2	Very high	92.2	Very high	125 Å²	125	52.2 Å²	52.2	81%	0.812	30%	0.296	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.4	-22.9	-178.2	-25.8	34.3	0	0	0	115.5	V214	P212-V214 PolarHBondContact O-N 3.48Å
213	A	90.3	Very high	92	Very high	3 Å²	3	54 Å²	54	3%	0.025	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	-76.6	-10.3	178.2	0	0	0	0	0	113.3	N211 T300 N301 Q304 T305	N211-A213 PolarHBondContact O-N 3.45Å; N211-A213 WeakPolarHBondContact OD1-CB 3.18Å; N211-A213 PolarHBondContact OD1-N 2.79Å; A213-T300 HydrophobicContact CB-CG2 4.35Å; A213-N301 PolarHBondContact O-N 3.31Å; A213-Q304 HydrophobicContact CB-CB 4.14Å; A213-T305 HydrophobicContact CB-CG2 3.8Å
214	V	92.2	Very high	91.7	Very high	20 Å²	20	54.4 Å²	54.4	12%	0.121	32%	0.321	C	S	.	.	B	Isolated β-bridge	trans	-97.6	122.3	-176	-176.8	0	0	0	0	109.5	A208 N211 P212 I296 L329	A208-V214 WeakPolarHBondContact O-CG2 3.06Å; N211-V214 HydrophobicContact CB-CG2 4Å; N211-V214 WeakPolarHBondContact O-CB 3.13Å; N211-V214 PolarHBondContact O-N 2.95Å; P212-V214 PolarHBondContact O-N 3.48Å; V214-I296 HydrophobicContact CG1-CG2 4.03Å; V214-I296 HydrophobicContact CG2-CG2 3.9Å; V214-L329 HydrophobicContact CG2-CD1 3.99Å; V214-L329 HydrophobicContact CG2-CD2 4.48Å
215	A	92.1	Very high	91.3	Very high	22 Å²	22	57.8 Å²	57.8	18%	0.182	34%	0.339	C	S	.	.			trans	-77.2	165.1	172.2	0	0	0	0	0	111.5	I217 I225 Y226 S299	A215-I217 PolarHBondContact O-N 3.32Å; A215-I225 HydrophobicContact CB-CD1 3.86Å; A215-I225 HydrophobicContact CB-CG2 4.25Å; A215-Y226 HydrophobicContact CB-CE2 3.74Å; A215-S299 PolarHBondContact N-O 3.49Å
216	D	92.1	Very high	90.9	Very high	107 Å²	107	62.2 Å²	62.2	57%	0.572	36%	0.355	S	S	*	.			trans	-57.4	114.9	176.4	-171.5	-47.5	0	0	0	110.8	G218 V219 S220	D216-G218 PolarHBondContact O-N 2.86Å; D216-G218 VanDerWaalsContact OD1-CA 3.31Å; D216-G218 WeakPolarHBondContact OD1-CA 3.16Å; D216-G218 PolarHBondContact OD1-N 3.45Å; D216-V219 HydrophobicContact CB-CB 4.35Å; D216-V219 HydrophobicContact CB-CG2 3.99Å; D216-V219 PolarHBondContact O-N 3.5Å; D216-V219 VanDerWaalsContact O-N 3.14Å; D216-V219 PolarHBondContact OD1-N 2.99Å; D216-S220 PolarHBondContact O-N 2.97Å; D216-S220 PolarHBondContact O-OG 2.93Å
217	I	91.1	Very high	90.5	Very high	30 Å²	30	59.9 Å²	59.9	15%	0.154	34%	0.338	C	S	.	.	H	α-helix	trans	-65.1	-25.1	-177.4	60.7	160.8	0	0	0	112.6	L209 A215 S220 A221 W230 L292 I296	L209-I217 HydrophobicContact CD2-CD1 3.86Å; L209-I217 HydrophobicContact CD2-CG1 4.02Å; L209-I217 HydrophobicContact CD2-CG2 3.69Å; A215-I217 PolarHBondContact O-N 3.32Å; I217-S220 VanDerWaalsContact CA-OG 3.3Å; I217-S220 WeakPolarHBondContact CA-OG 3.36Å; I217-S220 PolarHBondContact O-OG 3.11Å; I217-A221 WeakPolarHBondContact O-CB 3.03Å; I217-A221 PolarHBondContact O-N 2.97Å; I217-W230 WeakPolarHBondContact O-CZ2 3.46Å; I217-W230 PolarHBondContact O-NE1 3.38Å; I217-L292 HydrophobicContact CD1-CD2 4.1Å; I217-I296 HydrophobicContact CG2-CG1 4.27Å
218	G	90.5	Very high	90.2	Very high	45 Å²	45	58.6 Å²	58.6	46%	0.464	34%	0.339	S	S	.	.	H	α-helix	trans	-71.7	-31.3	176.3	0	0	0	0	0	112.6	D216 A221	D216-G218 PolarHBondContact O-N 2.86Å; D216-G218 VanDerWaalsContact OD1-CA 3.31Å; D216-G218 WeakPolarHBondContact OD1-CA 3.16Å; D216-G218 PolarHBondContact OD1-N 3.45Å; G218-A221 WeakPolarHBondContact O-CB 3.2Å
219	V	90.4	Very high	90.1	Very high	60 Å²	60	60.4 Å²	60.4	36%	0.364	35%	0.351	S	S	.	.	H	α-helix	trans	-78.4	-50	174.4	-178	0	0	0	0	110.2	D216 A221 K222 E223 I225	D216-V219 HydrophobicContact CB-CB 4.35Å; D216-V219 HydrophobicContact CB-CG2 3.99Å; D216-V219 PolarHBondContact O-N 3.5Å; D216-V219 VanDerWaalsContact O-N 3.14Å; D216-V219 PolarHBondContact OD1-N 2.99Å; V219-A221 PolarHBondContact O-N 2.96Å; V219-K222 PolarHBondContact O-N 3.44Å; V219-E223 HydrophobicContact CG1-CB 4.34Å; V219-E223 PolarHBondContact O-N 2.93Å; V219-I225 HydrophobicContact CB-CD1 4.18Å; V219-I225 HydrophobicContact CG1-CD1 3.96Å
220	S	90.4	Very high	90	Very high	6 Å²	6	58.7 Å²	58.7	4%	0.042	34%	0.34	C	S	.	.	H	α-helix	trans	-64.3	-14.2	178.3	68.9	0	0	0	0	113.6	D216 I217 K222 E223 P229 W230 S299	D216-S220 PolarHBondContact O-N 2.97Å; D216-S220 PolarHBondContact O-OG 2.93Å; I217-S220 VanDerWaalsContact CA-OG 3.3Å; I217-S220 WeakPolarHBondContact CA-OG 3.36Å; I217-S220 PolarHBondContact O-OG 3.11Å; S220-K222 PolarHBondContact O-N 3.28Å; S220-E223 WeakPolarHBondContact CA-O 3.29Å; S220-P229 VanDerWaalsContact O-CA 3.27Å; S220-P229 WeakPolarHBondContact O-CA 3.36Å; S220-W230 VanDerWaalsContact C-CD1 3.44Å; S220-W230 VanDerWaalsContact O-CD1 3.3Å; S220-W230 PolarHBondContact O-N 3.19Å; S220-W230 PolarHBondContact OG-NE1 3.07Å; S220-W230 VanDerWaalsContact OG-NE1 3.09Å; S220-S299 WeakPolarHBondContact CB-OG 3.49Å; S220-S299 PolarHBondContact OG-OG 2.81Å
221	A	89.9	Confident	90	Very high	8 Å²	8	57.8 Å²	57.8	7%	0.066	33%	0.328	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.8	-35.8	172.6	0	0	0	0	0	111.9	I217 G218 V219 P229 W230 L231	I217-A221 WeakPolarHBondContact O-CB 3.03Å; I217-A221 PolarHBondContact O-N 2.97Å; G218-A221 WeakPolarHBondContact O-CB 3.2Å; V219-A221 PolarHBondContact O-N 2.96Å; A221-P229 VanDerWaalsContact O-CB 3.24Å; A221-P229 WeakPolarHBondContact O-CB 3.29Å; A221-W230 HydrophobicContact CB-CD2 4.42Å; A221-W230 HydrophobicContact CB-CH2 4.29Å; A221-W230 HydrophobicContact CB-CZ2 3.48Å; A221-W230 VanDerWaalsContact CB-CZ2 3.48Å; A221-W230 VanDerWaalsContact N-NE1 3.12Å; A221-L231 HydrophobicContact CB-CD1 3.95Å; A221-L231 HydrophobicContact CB-CG 3.95Å; A221-L231 VanDerWaalsContact O-CB 3.27Å; A221-L231 WeakPolarHBondContact O-CB 3.24Å; A221-L231 VanDerWaalsContact O-CD1 3.31Å; A221-L231 WeakPolarHBondContact O-CD1 3.37Å; A221-L231 VanDerWaalsContact O-CG 3.24Å; A221-L231 WeakPolarHBondContact O-CG 3.3Å; A221-L231 PolarHBondContact O-N 2.87Å
222	K	89.5	Confident	89.8	Confident	163 Å²	163	56.9 Å²	56.9	71%	0.709	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-118.4	-28.7	-172.2	-63.5	178.4	-174.6	174.3	0	113	V219 S220 P229 L231	V219-K222 PolarHBondContact O-N 3.44Å; S220-K222 PolarHBondContact O-N 3.28Å; K222-P229 VanDerWaalsContact O-CG 3.28Å; K222-P229 WeakPolarHBondContact O-CG 3.4Å; K222-L231 HydrophobicContact CG-CD1 4.08Å
223	E	89.4	Confident	89.7	Confident	126 Å²	126	59.3 Å²	59.3	59%	0.589	33%	0.326	S	S	*	.	S	Bend	trans	-111.9	145.2	-175.6	-61.6	-175	-179.9	0	0	110.9	V219 S220 I225	V219-E223 HydrophobicContact CG1-CB 4.34Å; V219-E223 PolarHBondContact O-N 2.93Å; S220-E223 WeakPolarHBondContact CA-O 3.29Å; E223-I225 PolarHBondContact O-N 2.98Å
224	A	87.8	Confident	89.6	Confident	76 Å²	76	62 Å²	62	63%	0.628	34%	0.339	S	S	*	.			trans	-81.1	106.5	176.3	0	0	0	0	0	109.3	Q227	A224-Q227 VanDerWaalsContact CA-O 3.27Å; A224-Q227 WeakPolarHBondContact CA-O 3.35Å; A224-Q227 WeakPolarHBondContact CB-O 3.33Å
225	I	86.4	Confident	89.4	Confident	72 Å²	72	65.8 Å²	65.8	37%	0.369	35%	0.354	S	S	.	.	S	Bend	trans	-93.4	-71	174.9	-54.8	-176.7	0	0	0	109.5	A215 V219 E223	A215-I225 HydrophobicContact CB-CD1 3.86Å; A215-I225 HydrophobicContact CB-CG2 4.25Å; V219-I225 HydrophobicContact CB-CD1 4.18Å; V219-I225 HydrophobicContact CG1-CD1 3.96Å; E223-I225 PolarHBondContact O-N 2.98Å
226	Y	85.6	Confident	89.2	Confident	101 Å²	101	70.2 Å²	70.2	40%	0.396	38%	0.381	S	S	.	.	S	Bend	trans	-104.1	-23	177.9	-57.2	-59.6	0	0	0	112.8	A215 S299 N301	A215-Y226 HydrophobicContact CB-CE2 3.74Å; Y226-S299 WeakPolarHBondContact CD2-O 3.36Å; Y226-S299 VanDerWaalsContact CE2-O 3.26Å; Y226-S299 WeakPolarHBondContact CE2-O 3.32Å; Y226-N301 HydrophobicContact CD1-CB 4.26Å; Y226-N301 HydrophobicContact CE1-CB 3.74Å; Y226-N301 HydrophobicContact CE2-CB 4.02Å
227	Q	87.4	Confident	89	Confident	23 Å²	23	69.7 Å²	69.7	11%	0.107	38%	0.375	C	S	.	.	S	Bend	trans	-155.1	-178.1	175.8	60.4	174.4	32.5	0	0	110.3	Y78 P80 A224 A298	Y78-Q227 PolarHBondContact O-NE2 3.36Å; P80-Q227 HydrophobicContact CG-CB 4.45Å; A224-Q227 VanDerWaalsContact CA-O 3.27Å; A224-Q227 WeakPolarHBondContact CA-O 3.35Å; A224-Q227 WeakPolarHBondContact CB-O 3.33Å; Q227-A298 HydrophobicContact CG-CB 4.47Å; Q227-A298 WeakPolarHBondContact CG-O 3.44Å; Q227-A298 VanDerWaalsContact NE2-CA 3.27Å
228	S	87.9	Confident	88.8	Confident	54 Å²	54	69 Å²	69	38%	0.378	37%	0.372	S	S	.	.	S	Bend	trans	-51.7	147.1	175.5	-59.6	0	0	0	0	112	P80 W230	P80-S228 VanDerWaalsContact O-CB 3.28Å; P80-S228 WeakPolarHBondContact O-CB 3.4Å; S228-W230 PolarHBondContact O-N 3.44Å
229	P	91.4	Very high	88.8	Confident	39 Å²	39	70.6 Å²	70.6	25%	0.253	37%	0.37	S	S	.	.			trans	-58.4	132	-176.7	-21.4	30.6	0	0	0	112.5	S220 A221 K222 L231 G232	S220-P229 VanDerWaalsContact O-CA 3.27Å; S220-P229 WeakPolarHBondContact O-CA 3.36Å; A221-P229 VanDerWaalsContact O-CB 3.24Å; A221-P229 WeakPolarHBondContact O-CB 3.29Å; K222-P229 VanDerWaalsContact O-CG 3.28Å; K222-P229 WeakPolarHBondContact O-CG 3.4Å; P229-L231 PolarHBondContact O-N 3.37Å; P229-G232 PolarHBondContact O-N 3.39Å
230	W	91.8	Very high	88.9	Confident	29 Å²	29	76 Å²	76	11%	0.11	38%	0.383	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-12	-172.3	64.2	-100	0	0	0	113.9	V77 G83 L84 I217 S220 A221 S228 G232 A295 A298	V77-W230 HydrophobicContact CG1-CB 4.35Å; V77-W230 HydrophobicContact CG1-CE3 3.99Å; G83-W230 CarbonylContact C-O 3.12Å; G83-W230 WeakPolarHBondContact CA-O 3.32Å; L84-W230 HydrophobicContact CB-CE3 4.36Å; L84-W230 HydrophobicContact CB-CZ3 4.39Å; L84-W230 HydrophobicContact CD2-CZ3 4.14Å; L84-W230 PolarHBondContact N-O 3.33Å; I217-W230 WeakPolarHBondContact O-CZ2 3.46Å; I217-W230 PolarHBondContact O-NE1 3.38Å; S220-W230 VanDerWaalsContact C-CD1 3.44Å; S220-W230 VanDerWaalsContact O-CD1 3.3Å; S220-W230 PolarHBondContact O-N 3.19Å; S220-W230 PolarHBondContact OG-NE1 3.07Å; S220-W230 VanDerWaalsContact OG-NE1 3.09Å; A221-W230 HydrophobicContact CB-CD2 4.42Å; A221-W230 HydrophobicContact CB-CH2 4.29Å; A221-W230 HydrophobicContact CB-CZ2 3.48Å; A221-W230 VanDerWaalsContact CB-CZ2 3.48Å; A221-W230 VanDerWaalsContact N-NE1 3.12Å; S228-W230 PolarHBondContact O-N 3.44Å; W230-G232 PolarHBondContact O-N 3.47Å; W230-A295 HydrophobicContact CD2-CB 3.57Å; W230-A295 HydrophobicContact CE3-CB 3.85Å; W230-A295 HydrophobicContact CG-CB 3.92Å; W230-A295 HydrophobicContact CH2-CB 4.46Å; W230-A295 HydrophobicContact CZ2-CB 4.2Å; W230-A295 HydrophobicContact CZ3-CB 4.28Å; W230-A298 HydrophobicContact CB-CB 3.84Å
231	L	90.7	Very high	88.8	Confident	66 Å²	66	76.6 Å²	76.6	35%	0.346	39%	0.386	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-29.4	167.9	-77.8	174.5	0	0	0	111.7	L84 A85 A221 K222 P229	L84-L231 HydrophobicContact CD2-CD2 3.98Å; L84-L231 PolarHBondContact N-O 3.19Å; A85-L231 WeakPolarHBondContact CB-O 3.37Å; A85-L231 PolarHBondContact N-O 2.76Å; A221-L231 HydrophobicContact CB-CD1 3.95Å; A221-L231 HydrophobicContact CB-CG 3.95Å; A221-L231 VanDerWaalsContact O-CB 3.27Å; A221-L231 WeakPolarHBondContact O-CB 3.24Å; A221-L231 VanDerWaalsContact O-CD1 3.31Å; A221-L231 WeakPolarHBondContact O-CD1 3.37Å; A221-L231 VanDerWaalsContact O-CG 3.24Å; A221-L231 WeakPolarHBondContact O-CG 3.3Å; A221-L231 PolarHBondContact O-N 2.87Å; K222-L231 HydrophobicContact CG-CD1 4.08Å; P229-L231 PolarHBondContact O-N 3.37Å
232	G	88.6	Confident	88.9	Confident	20 Å²	20	79.1 Å²	79.1	21%	0.206	39%	0.394	C	S	.	.			trans	68.2	172.7	-176.8	0	0	0	0	0	113.5	Y82 P229 W230	Y82-G232 WeakPolarHBondContact O-CA 3.28Å; P229-G232 PolarHBondContact O-N 3.39Å; W230-G232 PolarHBondContact O-N 3.47Å
233	K	88.3	Confident	89.1	Confident	176 Å²	176	72.1 Å²	72.1	77%	0.765	37%	0.367	S	S	*	.			trans	-142.4	138.4	172.9	-67.4	-176.7	-177.8	174.7	0	109.5
234	I	89.3	Confident	89.2	Confident	59 Å²	59	66.1 Å²	66.1	30%	0.303	34%	0.339	S	S	.	.			trans	-84.3	117.4	170.7	-51.1	169.5	0	0	0	106.9	A85 N239 W242	A85-I234 HydrophobicContact CB-CG1 4.03Å; I234-N239 WeakPolarHBondContact CG2-OD1 3.38Å; I234-W242 HydrophobicContact CD1-CD2 3.84Å; I234-W242 HydrophobicContact CD1-CG 3.93Å; I234-W242 HydrophobicContact CD1-CZ2 4.15Å; I234-W242 HydrophobicContact CG1-CG 4.4Å; I234-W242 HydrophobicContact CG2-CB 4.17Å; I234-W242 HydrophobicContact CG2-CG 4.18Å
235	K	87.9	Confident	89.3	Confident	100 Å²	100	63.4 Å²	63.4	44%	0.435	31%	0.313	S	S	.	.			trans	-72.7	143.5	175.7	-61.4	176.4	-173.3	164.3	0	108.9	E237 D238 N239	K235-E237 HydrophobicContact CB-CG 3.81Å; K235-E237 WeakPolarHBondContact CD-OE1 3.23Å; K235-E237 PolarHBondContact O-N 2.98Å; K235-D238 PolarHBondContact O-N 3.45Å; K235-N239 PolarHBondContact O-N 3.25Å; K235-N239 PolarHBondContact O-OD1 3.29Å
236	P	87.3	Confident	89.5	Confident	114 Å²	114	61.8 Å²	61.8	74%	0.74	30%	0.304	S	S	*	.	G	3₁₀ helix	trans	-55.4	-29.5	-179.7	-27.6	35.1	0	0	0	114.4	D238 N239	P236-D238 VanDerWaalsContact C-N 3.32Å; P236-N239 PolarHBondContact O-ND2 3.46Å
237	E	87.1	Confident	89.9	Confident	96 Å²	96	61.1 Å²	61.1	45%	0.449	30%	0.303	S	S	.	.	G	3₁₀ helix	trans	-69.9	-26	177.5	58.4	-177.7	174	0	0	114.1	K235 R487	K235-E237 HydrophobicContact CB-CG 3.81Å; K235-E237 WeakPolarHBondContact CD-OE1 3.23Å; K235-E237 PolarHBondContact O-N 2.98Å; E237-R487 IonicContact OE1-NH2 3.27Å; E237-R487 PolarHBondContact OE1-NH2 3.42Å; E237-R487 IonicContact OE2-CZ 2.6Å; E237-R487 VanDerWaalsContact OE2-CZ 3.3Å; E237-R487 IonicContact OE2-NH1 3.74Å; E237-R487 PolarHBondContact OE2-NH1 2.95Å; E237-R487 IonicContact OE2-NH2 3.47Å; E237-R487 PolarHBondContact OE2-NH2 3.45Å; E237-R487 VanDerWaalsContact OE2-NH2 3.11Å
238	D	88.4	Confident	90.1	Very high	17 Å²	17	60.1 Å²	60.1	9%	0.091	30%	0.299	C	S	.	.	G	3₁₀ helix	trans	-99.8	0.4	-177.2	-59	-38.4	0	0	0	112.4	W86 K235 P236 W240 L241 W242 R487	W86-D238 HydrophobicContact CH2-CB 3.87Å; W86-D238 HydrophobicContact CZ2-CB 3.68Å; K235-D238 PolarHBondContact O-N 3.45Å; P236-D238 VanDerWaalsContact C-N 3.32Å; D238-W240 PolarHBondContact O-N 3.44Å; D238-W240 VanDerWaalsContact O-N 3.17Å; D238-L241 PolarHBondContact O-N 2.63Å; D238-L241 VanDerWaalsContact O-N 3.11Å; D238-W242 WeakPolarHBondContact O-CB 3.44Å; D238-W242 PolarHBondContact O-N 3.25Å; D238-R487 IonicContact OD1-CZ 3.4Å; D238-R487 IonicContact OD1-NE 3.12Å; D238-R487 PolarHBondContact OD1-NE 3.02Å; D238-R487 IonicContact OD1-NH2 3.36Å
239	N	90.6	Very high	90.2	Very high	78 Å²	78	58.1 Å²	58.1	42%	0.417	28%	0.284	S	S	.	.	H	α-helix	trans	-53.2	-40.2	-177.8	-78.6	-11.9	0	0	0	112.9	I234 K235 P236 A243	I234-N239 WeakPolarHBondContact CG2-OD1 3.38Å; K235-N239 PolarHBondContact O-N 3.25Å; K235-N239 PolarHBondContact O-OD1 3.29Å; P236-N239 PolarHBondContact O-ND2 3.46Å; N239-A243 WeakPolarHBondContact O-CB 3.14Å; N239-A243 PolarHBondContact O-N 3.47Å
240	W	91.1	Very high	90.2	Very high	172 Å²	172	57.2 Å²	57.2	65%	0.652	28%	0.276	S	S	*	.	H	α-helix	trans	-75.5	-37.6	178.6	-72.4	153.4	0	0	0	113.8	D238 W242 A243 D244 R487 P489	D238-W240 PolarHBondContact O-N 3.44Å; D238-W240 VanDerWaalsContact O-N 3.17Å; W240-W242 VanDerWaalsContact C-N 3.32Å; W240-A243 HydrophobicContact CE3-CB 4.25Å; W240-A243 PolarHBondContact O-N 2.95Å; W240-D244 WeakPolarHBondContact O-CB 3.38Å; W240-D244 PolarHBondContact O-N 2.86Å; W240-R487 VanDerWaalsContact CB-O 3.29Å; W240-R487 WeakPolarHBondContact CB-O 3.47Å; W240-P489 HydrophobicContact CB-CB 4.5Å; W240-P489 HydrophobicContact CB-CG 4.3Å; W240-P489 HydrophobicContact CG-CG 4.48Å
241	L	89.3	Confident	90.3	Very high	19 Å²	19	57.1 Å²	57.1	10%	0.099	28%	0.278	C	S	.	.	H	α-helix	trans	-62.1	-44.3	171.5	176.8	61.4	0	0	0	110.9	W86 D238 D244 N245 Q485 R487	W86-L241 HydrophobicContact CH2-CD2 4.21Å; W86-L241 HydrophobicContact CH2-CG 4.37Å; D238-L241 PolarHBondContact O-N 2.63Å; D238-L241 VanDerWaalsContact O-N 3.11Å; L241-D244 PolarHBondContact O-N 3.21Å; L241-N245 PolarHBondContact O-N 3.49Å; L241-N245 PolarHBondContact O-ND2 2.95Å; L241-Q485 HydrophobicContact CD2-CG 4.49Å; L241-R487 PolarHBondContact N-O 3.25Å
242	W	91.2	Very high	90.3	Very high	61 Å²	61	54 Å²	54	23%	0.231	26%	0.261	C	S	.	.	H	α-helix	trans	-59.7	-48.9	177.2	-171.5	99	0	0	0	110.8	A85 W86 Q88 I234 D238 W240 D244 N245 F246	A85-W242 PolarHBondContact O-NE1 3.26Å; W86-W242 AromaticContact CD2-CD1 3.78Å; W86-W242 AromaticContact CE3-CD1 3.8Å; W86-W242 HydrophobicContact CH2-CB 4.2Å; W86-W242 HydrophobicContact CZ3-CB 4.31Å; Q88-W242 HydrophobicContact CG-CZ2 3.86Å; Q88-W242 PolarHBondContact NE2-O 2.93Å; I234-W242 HydrophobicContact CD1-CD2 3.84Å; I234-W242 HydrophobicContact CD1-CG 3.93Å; I234-W242 HydrophobicContact CD1-CZ2 4.15Å; I234-W242 HydrophobicContact CG1-CG 4.4Å; I234-W242 HydrophobicContact CG2-CB 4.17Å; I234-W242 HydrophobicContact CG2-CG 4.18Å; D238-W242 WeakPolarHBondContact O-CB 3.44Å; D238-W242 PolarHBondContact O-N 3.25Å; W240-W242 VanDerWaalsContact C-N 3.32Å; W242-D244 PolarHBondContact O-N 3.49Å; W242-N245 PolarHBondContact O-N 3.44Å; W242-F246 HydrophobicContact CE3-CB 4.23Å; W242-F246 HydrophobicContact CH2-CB 4.32Å; W242-F246 AromaticContact CH2-CD2 3.87Å; W242-F246 HydrophobicContact CH2-CD2 3.87Å; W242-F246 HydrophobicContact CH2-CE2 4.42Å; W242-F246 HydrophobicContact CH2-CG 4.06Å; W242-F246 HydrophobicContact CZ2-CD2 4.47Å; W242-F246 HydrophobicContact CZ3-CB 3.93Å; W242-F246 HydrophobicContact CZ3-CD2 4.28Å; W242-F246 AromaticContact CZ3-CG 3.98Å; W242-F246 HydrophobicContact CZ3-CG 3.98Å; W242-F246 WeakPolarHBondContact O-CB 3.14Å; W242-F246 PolarHBondContact O-N 3.09Å
243	A	93.1	Very high	90.2	Very high	17 Å²	17	53 Å²	53	14%	0.14	25%	0.251	C	S	.	.	H	α-helix	trans	-63	-41.1	177.7	0	0	0	0	0	112	N239 W240 F246 F247	N239-A243 WeakPolarHBondContact O-CB 3.14Å; N239-A243 PolarHBondContact O-N 3.47Å; W240-A243 HydrophobicContact CE3-CB 4.25Å; W240-A243 PolarHBondContact O-N 2.95Å; A243-F246 PolarHBondContact O-N 3.08Å; A243-F247 HydrophobicContact CB-CD2 4.48Å; A243-F247 HydrophobicContact CB-CE2 4.28Å; A243-F247 WeakPolarHBondContact O-CD2 3.48Å; A243-F247 PolarHBondContact O-N 3.34Å
244	D	92.2	Very high	90.4	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-61.6	-46.5	178.9	-159.1	26	0	0	0	111.9	W240 L241 W242 F246 F247 L248 P489 F490 K491 S492	W240-D244 WeakPolarHBondContact O-CB 3.38Å; W240-D244 PolarHBondContact O-N 2.86Å; L241-D244 PolarHBondContact O-N 3.21Å; W242-D244 PolarHBondContact O-N 3.49Å; D244-F246 VanDerWaalsContact C-N 3.33Å; D244-F246 PolarHBondContact O-N 2.84Å; D244-F247 PolarHBondContact O-N 3.01Å; D244-L248 WeakPolarHBondContact O-CB 3.41Å; D244-L248 PolarHBondContact O-N 3.47Å; D244-P489 HydrophobicContact CB-CB 3.69Å; D244-P489 VanDerWaalsContact CG-C 3.49Å; D244-P489 WeakPolarHBondContact OD2-CA 3.22Å; D244-F490 PolarHBondContact OD2-N 3.39Å; D244-K491 WeakPolarHBondContact OD2-CB 3.19Å; D244-K491 WeakPolarHBondContact OD2-CG 3.31Å; D244-K491 PolarHBondContact OD2-N 3.19Å; D244-S492 WeakPolarHBondContact OD1-CB 3.46Å; D244-S492 PolarHBondContact OD1-N 3.31Å; D244-S492 PolarHBondContact OD1-OG 3.49Å
245	N	89.3	Confident	90.6	Very high	18 Å²	18	42.2 Å²	42.2	10%	0.096	20%	0.203	C	C	.	.	H	α-helix	trans	-63.1	-40.1	174.9	-71.8	-20.7	0	0	0	111.6	Q88 L241 W242 L248 L249 Y409	Q88-N245 VanDerWaalsContact OE1-C 3.28Å; L241-N245 PolarHBondContact O-N 3.49Å; L241-N245 PolarHBondContact O-ND2 2.95Å; W242-N245 PolarHBondContact O-N 3.44Å; N245-L248 PolarHBondContact O-N 3.43Å; N245-L249 WeakPolarHBondContact O-CG 3.35Å; N245-L249 PolarHBondContact O-N 2.84Å; N245-Y409 WeakPolarHBondContact OD1-CE2 3.24Å; N245-Y409 PolarHBondContact OD1-OH 3.32Å
246	F	91.9	Very high	90.7	Very high	38 Å²	38	37.7 Å²	37.7	17%	0.167	18%	0.183	C	C	.	.	H	α-helix	trans	-65.3	-44.1	179.7	-174.9	-97.9	0	0	0	111.5	Q88 F91 L95 W242 A243 D244 L249 M250	Q88-F246 HydrophobicContact CB-CD2 4.22Å; Q88-F246 HydrophobicContact CG-CD2 4.3Å; Q88-F246 VanDerWaalsContact OE1-CA 3.27Å; F91-F246 HydrophobicContact CB-CE2 4.24Å; L95-F246 HydrophobicContact CD2-CE1 4.49Å; L95-F246 HydrophobicContact CD2-CZ 4.33Å; W242-F246 HydrophobicContact CE3-CB 4.23Å; W242-F246 HydrophobicContact CH2-CB 4.32Å; W242-F246 AromaticContact CH2-CD2 3.87Å; W242-F246 HydrophobicContact CH2-CD2 3.87Å; W242-F246 HydrophobicContact CH2-CE2 4.42Å; W242-F246 HydrophobicContact CH2-CG 4.06Å; W242-F246 HydrophobicContact CZ2-CD2 4.47Å; W242-F246 HydrophobicContact CZ3-CB 3.93Å; W242-F246 HydrophobicContact CZ3-CD2 4.28Å; W242-F246 AromaticContact CZ3-CG 3.98Å; W242-F246 HydrophobicContact CZ3-CG 3.98Å; W242-F246 WeakPolarHBondContact O-CB 3.14Å; W242-F246 PolarHBondContact O-N 3.09Å; A243-F246 PolarHBondContact O-N 3.08Å; D244-F246 VanDerWaalsContact C-N 3.33Å; D244-F246 PolarHBondContact O-N 2.84Å; F246-L249 PolarHBondContact O-N 2.92Å; F246-M250 HydrophobicContact CE1-SD 4.22Å; F246-M250 VanDerWaalsContact O-CB 3.29Å; F246-M250 WeakPolarHBondContact O-CB 3.34Å; F246-M250 PolarHBondContact O-N 3.48Å
247	F	93.8	Very high	91	Very high	88 Å²	88	32.5 Å²	32.5	39%	0.386	15%	0.149	S	C	.	.	H	α-helix	trans	-64.8	-38.8	174.7	-73.6	-59.5	0	0	0	112.2	A243 D244 M250 L251 Y416	A243-F247 HydrophobicContact CB-CD2 4.48Å; A243-F247 HydrophobicContact CB-CE2 4.28Å; A243-F247 WeakPolarHBondContact O-CD2 3.48Å; A243-F247 PolarHBondContact O-N 3.34Å; D244-F247 PolarHBondContact O-N 3.01Å; F247-M250 HydrophobicContact CD1-CE 3.39Å; F247-M250 HydrophobicContact CE1-CE 3.7Å; F247-M250 PolarHBondContact O-N 3.45Å; F247-L251 HydrophobicContact CD1-CD1 4.34Å; F247-L251 VanDerWaalsContact O-CB 3.3Å; F247-L251 WeakPolarHBondContact O-CB 3.16Å; F247-L251 PolarHBondContact O-N 2.78Å; F247-Y416 WeakPolarHBondContact CB-OH 3.11Å
248	L	91.3	Very high	91.1	Very high	1 Å²	1	27.9 Å²	27.9	1%	0.005	13%	0.128	C	C	.	.	H	α-helix	trans	-59.7	-45.9	174.6	178.3	154	0	0	0	111.5	D244 N245 G252 Y409 D413 Y416 K491	D244-L248 WeakPolarHBondContact O-CB 3.41Å; D244-L248 PolarHBondContact O-N 3.47Å; N245-L248 PolarHBondContact O-N 3.43Å; L248-G252 WeakPolarHBondContact O-CA 3.28Å; L248-G252 PolarHBondContact O-N 3.22Å; L248-Y409 HydrophobicContact CD1-CE1 4.16Å; L248-D413 HydrophobicContact CD1-CB 4.21Å; L248-Y416 HydrophobicContact CB-CD1 3.73Å; L248-Y416 HydrophobicContact CB-CE1 3.99Å; L248-Y416 HydrophobicContact CB-CG 4.26Å; L248-Y416 HydrophobicContact CD1-CD1 4.12Å; L248-Y416 HydrophobicContact CG-CD1 3.88Å; L248-Y416 HydrophobicContact CG-CG 4.22Å; L248-K491 HydrophobicContact CD1-CD 3.75Å
249	L	89.3	Confident	91.3	Very high	13 Å²	13	27.2 Å²	27.2	7%	0.068	12%	0.124	C	C	.	.	H	α-helix	trans	-68.4	-43	178.4	-65.7	169.8	0	0	0	111.9	Q88 Y93 N245 F246 G253 W408	Q88-L249 HydrophobicContact CB-CD1 3.73Å; Y93-L249 HydrophobicContact CE1-CD2 4.4Å; Y93-L249 HydrophobicContact CE2-CD2 3.84Å; Y93-L249 VanDerWaalsContact OH-CD2 3.29Å; Y93-L249 WeakPolarHBondContact OH-CD2 3.47Å; N245-L249 WeakPolarHBondContact O-CG 3.35Å; N245-L249 PolarHBondContact O-N 2.84Å; F246-L249 PolarHBondContact O-N 2.92Å; L249-G253 PolarHBondContact O-N 3.01Å; L249-W408 HydrophobicContact CD2-CH2 3.81Å; L249-W408 HydrophobicContact CD2-CZ2 4.43Å; L249-W408 HydrophobicContact CD2-CZ3 4.26Å
250	M	92.3	Very high	91.4	Very high	19 Å²	19	23.5 Å²	23.5	9%	0.094	10%	0.104	C	C	.	.	H	α-helix	trans	-69.4	-43.9	-178.1	178.7	-178.1	61.5	0	0	113.3	G92 L95 S96 L99 F246 F247	G92-M250 WeakPolarHBondContact O-CA 3.28Å; L95-M250 HydrophobicContact CB-CG 4.13Å; L95-M250 HydrophobicContact CB-SD 4.3Å; L95-M250 HydrophobicContact CD2-CG 4.12Å; L95-M250 HydrophobicContact CD2-SD 3.21Å; L95-M250 WeakPolarHBondContact CD2-SD 3.12Å; L95-M250 HydrophobicContact CG-CG 3.92Å; L95-M250 HydrophobicContact CG-SD 3.55Å; L95-M250 VanDerWaalsContact CG-SD 3.55Å; S96-M250 VanDerWaalsContact CA-O 3.25Å; S96-M250 WeakPolarHBondContact CA-O 3.42Å; S96-M250 WeakPolarHBondContact CB-O 3.22Å; S96-M250 PolarHBondContact OG-O 3.1Å; L99-M250 HydrophobicContact CD1-CG 3.88Å; L99-M250 HydrophobicContact CD1-SD 3.8Å; F246-M250 HydrophobicContact CE1-SD 4.22Å; F246-M250 VanDerWaalsContact O-CB 3.29Å; F246-M250 WeakPolarHBondContact O-CB 3.34Å; F246-M250 PolarHBondContact O-N 3.48Å; F247-M250 HydrophobicContact CD1-CE 3.39Å; F247-M250 HydrophobicContact CE1-CE 3.7Å; F247-M250 PolarHBondContact O-N 3.45Å
251	L	93.9	Very high	91.3	Very high	27 Å²	27	15.3 Å²	15.3	14%	0.141	7%	0.073	C	C	.	.	H	α-helix	trans	-98.7	-33.2	-173.5	-60	178.7	0	0	0	111.9	L99 F247 G253 I254 P255 Y416 F420 M495	L99-L251 HydrophobicContact CD1-CD2 4.25Å; F247-L251 HydrophobicContact CD1-CD1 4.34Å; F247-L251 VanDerWaalsContact O-CB 3.3Å; F247-L251 WeakPolarHBondContact O-CB 3.16Å; F247-L251 PolarHBondContact O-N 2.78Å; L251-G253 VanDerWaalsContact C-N 3.25Å; L251-G253 PolarHBondContact O-N 3.09Å; L251-I254 HydrophobicContact CD2-CD1 4.2Å; L251-I254 PolarHBondContact O-N 2.81Å; L251-P255 WeakPolarHBondContact O-CD 3.4Å; L251-Y416 HydrophobicContact CB-CD2 3.89Å; L251-Y416 HydrophobicContact CB-CE2 3.58Å; L251-Y416 HydrophobicContact CD1-CE2 4Å; L251-Y416 HydrophobicContact CG-CE2 4.36Å; L251-F420 HydrophobicContact CB-CD1 4.02Å; L251-F420 HydrophobicContact CB-CE1 3.78Å; L251-F420 HydrophobicContact CB-CE2 4.32Å; L251-F420 HydrophobicContact CB-CG 4.4Å; L251-F420 HydrophobicContact CB-CZ 3.93Å; L251-F420 HydrophobicContact CD1-CE1 3.85Å; L251-F420 HydrophobicContact CD1-CZ 4.3Å; L251-F420 HydrophobicContact CD2-CE1 4.18Å; L251-F420 HydrophobicContact CD2-CE2 4.47Å; L251-F420 HydrophobicContact CD2-CZ 3.77Å; L251-F420 HydrophobicContact CG-CE1 4.14Å; L251-F420 HydrophobicContact CG-CZ 4.21Å; L251-F420 WeakPolarHBondContact O-CD2 3.27Å; L251-M495 HydrophobicContact CD1-CE 4.19Å
252	G	89.8	Confident	91.3	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-67.7	-23.8	175.1	0	0	0	0	0	113.5	L248 I254 P255 W256	L248-G252 WeakPolarHBondContact O-CA 3.28Å; L248-G252 PolarHBondContact O-N 3.22Å; G252-I254 VanDerWaalsContact C-N 3.32Å; G252-P255 WeakPolarHBondContact O-CD 3.36Å; G252-W256 PolarHBondContact O-NE1 3.32Å
253	G	87.8	Confident	91.3	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.058	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.2	-16.8	174.1	0	0	0	0	0	114.7	W64 S96 L249 L251	W64-G253 VanDerWaalsContact CH2-O 3.23Å; W64-G253 WeakPolarHBondContact CH2-O 3.28Å; W64-G253 VanDerWaalsContact CZ2-O 3.28Å; W64-G253 WeakPolarHBondContact CZ2-O 3.3Å; S96-G253 WeakPolarHBondContact OG-CA 3.29Å; L249-G253 PolarHBondContact O-N 3.01Å; L251-G253 VanDerWaalsContact C-N 3.25Å; L251-G253 PolarHBondContact O-N 3.09Å
254	I	92.8	Very high	91	Very high	1 Å²	1	10.8 Å²	10.8	1%	0.005	5%	0.051	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.4	-54.1	-178.1	-61.4	172.4	0	0	0	112.1	S96 L99 F104 L251 G252 W256 F260 F420 L423	S96-I254 WeakPolarHBondContact OG-CG1 3.38Å; S96-I254 PolarHBondContact OG-N 3.46Å; L99-I254 HydrophobicContact CB-CD1 3.98Å; F104-I254 HydrophobicContact CB-CG2 4.49Å; F104-I254 HydrophobicContact CD1-CG2 4.18Å; F104-I254 HydrophobicContact CD2-CG2 3.69Å; F104-I254 HydrophobicContact CE1-CG2 4.31Å; F104-I254 HydrophobicContact CE2-CD1 4.03Å; F104-I254 HydrophobicContact CE2-CG2 3.84Å; F104-I254 HydrophobicContact CG-CG2 3.87Å; F104-I254 HydrophobicContact CZ-CG2 4.14Å; L251-I254 HydrophobicContact CD2-CD1 4.2Å; L251-I254 PolarHBondContact O-N 2.81Å; G252-I254 VanDerWaalsContact C-N 3.32Å; I254-W256 PolarHBondContact O-N 3.38Å; I254-F260 HydrophobicContact CG2-CZ 4.47Å; I254-F260 WeakPolarHBondContact O-CE2 3.48Å; I254-F420 HydrophobicContact CB-CD2 4.38Å; I254-F420 HydrophobicContact CB-CE2 4.3Å; I254-F420 HydrophobicContact CD1-CE2 3.88Å; I254-L423 HydrophobicContact CG2-CD2 4Å
255	P	93.2	Very high	90.7	Very high	7 Å²	7	10.9 Å²	10.9	5%	0.045	5%	0.051	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.8	19.9	-174	33.4	-41.6	0	0	0	114.8	M116 L251 G252 V415 I419 F420 L423	M116-P255 HydrophobicContact CE-CB 3.65Å; L251-P255 WeakPolarHBondContact O-CD 3.4Å; G252-P255 WeakPolarHBondContact O-CD 3.36Å; P255-V415 HydrophobicContact CB-CG1 4.28Å; P255-V415 HydrophobicContact CG-CG1 3.47Å; P255-V415 VanDerWaalsContact CG-CG1 3.47Å; P255-I419 HydrophobicContact CB-CB 4.19Å; P255-I419 HydrophobicContact CB-CG2 3.61Å; P255-I419 HydrophobicContact CG-CB 4.47Å; P255-I419 HydrophobicContact CG-CG2 4.39Å; P255-F420 HydrophobicContact CG-CB 3.97Å; P255-F420 HydrophobicContact CG-CD2 4.48Å; P255-L423 HydrophobicContact CB-CD2 4.17Å
256	W	90.5	Very high	90.6	Very high	6 Å²	6	10 Å²	10	2%	0.023	5%	0.047	C	C	.	.			trans	-79.8	130.1	-179.5	-89	42.4	0	0	0	111.7	W64 W143 G252 I254 V258 Y259 F260	W64-W256 HydrophobicContact CH2-CD2 4.3Å; W64-W256 HydrophobicContact CH2-CE3 4.13Å; W64-W256 HydrophobicContact CH2-CG 4.42Å; W64-W256 HydrophobicContact CZ3-CE3 4.33Å; W64-W256 HydrophobicContact CZ3-CZ3 4.44Å; W143-W256 HydrophobicContact CB-CH2 3.76Å; W143-W256 HydrophobicContact CB-CZ2 4.47Å; W143-W256 HydrophobicContact CB-CZ3 4.48Å; W143-W256 AromaticContact CD1-CH2 3.92Å; W143-W256 HydrophobicContact CD2-CE3 4.34Å; W143-W256 AromaticContact CD2-CH2 3.25Å; W143-W256 HydrophobicContact CD2-CH2 3.25Å; W143-W256 AromaticContact CD2-CZ3 3.14Å; W143-W256 HydrophobicContact CD2-CZ3 3.14Å; W143-W256 AromaticContact CE2-CH2 3.73Å; W143-W256 AromaticContact CE2-CZ3 3.47Å; W143-W256 VanDerWaalsContact CE2-CZ3 3.47Å; W143-W256 AromaticContact CE3-CE3 3.85Å; W143-W256 HydrophobicContact CE3-CE3 3.85Å; W143-W256 AromaticContact CE3-CH2 3.55Å; W143-W256 HydrophobicContact CE3-CH2 3.55Å; W143-W256 AromaticContact CE3-CZ3 3.02Å; W143-W256 HydrophobicContact CE3-CZ3 3.02Å; W143-W256 AromaticContact CG-CH2 3.37Å; W143-W256 HydrophobicContact CG-CH2 3.37Å; W143-W256 HydrophobicContact CG-CZ2 4.45Å; W143-W256 AromaticContact CG-CZ3 3.83Å; W143-W256 HydrophobicContact CG-CZ3 3.83Å; W143-W256 HydrophobicContact CH2-CE3 4.27Å; W143-W256 AromaticContact CH2-CZ3 3.62Å; W143-W256 HydrophobicContact CH2-CZ3 3.62Å; W143-W256 HydrophobicContact CZ2-CH2 4.41Å; W143-W256 AromaticContact CZ2-CZ3 3.71Å; W143-W256 HydrophobicContact CZ2-CZ3 3.71Å; W143-W256 AromaticContact CZ3-CE3 3.83Å; W143-W256 HydrophobicContact CZ3-CE3 3.83Å; W143-W256 HydrophobicContact CZ3-CH2 4.24Å; W143-W256 AromaticContact CZ3-CZ3 3.28Å; W143-W256 HydrophobicContact CZ3-CZ3 3.28Å; G252-W256 PolarHBondContact O-NE1 3.32Å; I254-W256 PolarHBondContact O-N 3.38Å; W256-V258 HydrophobicContact CE3-CG2 4.36Å; W256-V258 PolarHBondContact O-N 2.55Å; W256-Y259 PolarHBondContact O-N 3.36Å; W256-F260 WeakPolarHBondContact O-CD2 3.28Å; W256-F260 PolarHBondContact O-N 2.74Å; W256-F260 VanDerWaalsContact O-N 3.1Å
257	Q	91.8	Very high	90.1	Very high	4 Å²	4	10.2 Å²	10.2	2%	0.019	5%	0.053	C	C	.	.	H	α-helix	trans	-62	-34.9	176.8	166.2	71.2	8.5	0	0	110.8	M116 Y259 F260 Q261 S356 M360	M116-Q257 HydrophobicContact CB-CB 4.29Å; Q257-Y259 VanDerWaalsContact C-N 3.28Å; Q257-Y259 PolarHBondContact O-N 3.31Å; Q257-F260 CarbonylContact O-C 3.44Å; Q257-F260 PolarHBondContact O-N 3Å; Q257-Q261 VanDerWaalsContact O-CB 3.23Å; Q257-Q261 WeakPolarHBondContact O-CB 3.44Å; Q257-Q261 PolarHBondContact O-N 3.15Å; Q257-S356 WeakPolarHBondContact CB-OG 3.11Å; Q257-S356 WeakPolarHBondContact CG-OG 3.29Å; Q257-M360 HydrophobicContact CB-CE 3.72Å; Q257-M360 HydrophobicContact CB-CG 4.03Å; Q257-M360 HydrophobicContact CB-SD 3.52Å; Q257-M360 VanDerWaalsContact CB-SD 3.52Å; Q257-M360 HydrophobicContact CG-CE 4.08Å; Q257-M360 HydrophobicContact CG-CG 3.67Å; Q257-M360 HydrophobicContact CG-SD 3.89Å
258	V	90.3	Very high	89.8	Confident	0 Å²	0	7.9 Å²	7.9	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-61	-40.8	-179.1	-159	0	0	0	0	111.7	T63 E140 W143 W256 R262 S356	T63-V258 HydrophobicContact CG2-CB 4.01Å; T63-V258 HydrophobicContact CG2-CG1 3.27Å; E140-V258 WeakPolarHBondContact OE1-CG2 3.48Å; E140-V258 VanDerWaalsContact OE2-CG2 3.32Å; E140-V258 WeakPolarHBondContact OE2-CG2 3.15Å; W143-V258 HydrophobicContact CE3-CG2 4.28Å; W143-V258 HydrophobicContact CZ3-CB 4.22Å; W143-V258 HydrophobicContact CZ3-CG1 4.28Å; W143-V258 HydrophobicContact CZ3-CG2 3.63Å; W256-V258 HydrophobicContact CE3-CG2 4.36Å; W256-V258 PolarHBondContact O-N 2.55Å; V258-R262 WeakPolarHBondContact O-CD 3.47Å; V258-R262 PolarHBondContact O-NH1 2.94Å; V258-S356 PolarHBondContact N-OG 3.12Å
259	Y	92.3	Very high	89.6	Confident	3 Å²	3	8.8 Å²	8.8	1%	0.012	6%	0.055	C	C	.	.	H	α-helix	trans	-64.4	-52.2	172.7	168.4	-115.3	0	0	0	111.4	M60 L97 G100 G101 W256 Q257 Q261 R262 V263 S276	M60-Y259 HydrophobicContact CE-CD2 4.49Å; M60-Y259 HydrophobicContact CE-CE2 4.22Å; M60-Y259 HydrophobicContact SD-CD2 4.35Å; M60-Y259 HydrophobicContact SD-CE2 3.99Å; L97-Y259 HydrophobicContact CD2-CD2 3.59Å; L97-Y259 HydrophobicContact CD2-CE2 3.55Å; G100-Y259 PolarHBondContact O-OH 3.01Å; G101-Y259 PolarHBondContact N-OH 3.3Å; W256-Y259 PolarHBondContact O-N 3.36Å; Q257-Y259 VanDerWaalsContact C-N 3.28Å; Q257-Y259 PolarHBondContact O-N 3.31Å; Y259-Q261 VanDerWaalsContact C-N 3.26Å; Y259-Q261 PolarHBondContact O-N 2.69Å; Y259-R262 PolarHBondContact O-N 3.42Å; Y259-R262 VanDerWaalsContact O-N 3.12Å; Y259-V263 HydrophobicContact CD1-CG2 4.4Å; Y259-V263 HydrophobicContact CD2-CG2 4.1Å; Y259-V263 HydrophobicContact CE1-CG2 3.9Å; Y259-V263 HydrophobicContact CE2-CG2 3.55Å; Y259-V263 HydrophobicContact CG-CG2 4.49Å; Y259-V263 VanDerWaalsContact CZ-CG2 3.44Å; Y259-V263 PolarHBondContact O-N 2.7Å; Y259-V263 VanDerWaalsContact O-N 3.1Å; Y259-S276 PolarHBondContact OH-OG 3.3Å
260	F	91.9	Very high	89.5	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-65	-29.6	-178.9	-79.5	-64.9	0	0	0	113	F104 M108 M116 I254 W256 Q257 R262 V263 L264 L423	F104-F260 HydrophobicContact CB-CE1 3.99Å; F104-F260 HydrophobicContact CB-CZ 3.75Å; F104-F260 HydrophobicContact CG-CZ 4.48Å; M108-F260 HydrophobicContact CB-CD1 4.03Å; M108-F260 HydrophobicContact CB-CE1 3.95Å; M108-F260 HydrophobicContact CE-CD1 3.97Å; M108-F260 HydrophobicContact CE-CE1 4.22Å; M108-F260 HydrophobicContact CE-CG 4.16Å; M108-F260 HydrophobicContact CG-CD1 3.94Å; M108-F260 HydrophobicContact CG-CE1 3.49Å; M108-F260 VanDerWaalsContact CG-CE1 3.49Å; M108-F260 HydrophobicContact CG-CZ 4.14Å; M116-F260 HydrophobicContact CB-CB 4.23Å; M116-F260 HydrophobicContact CB-CD2 4.05Å; M116-F260 HydrophobicContact CB-CG 4.42Å; M116-F260 HydrophobicContact CE-CD2 4.29Å; M116-F260 HydrophobicContact CE-CE2 3.9Å; M116-F260 HydrophobicContact CG-CD2 3.78Å; M116-F260 HydrophobicContact CG-CE2 4.29Å; M116-F260 HydrophobicContact SD-CD2 3.26Å; M116-F260 WeakPolarHBondContact SD-CD2 3.12Å; M116-F260 HydrophobicContact SD-CE2 3.29Å; M116-F260 WeakPolarHBondContact SD-CE2 3.21Å; M116-F260 HydrophobicContact SD-CG 4.04Å; M116-F260 HydrophobicContact SD-CZ 4.13Å; I254-F260 HydrophobicContact CG2-CZ 4.47Å; I254-F260 WeakPolarHBondContact O-CE2 3.48Å; W256-F260 WeakPolarHBondContact O-CD2 3.28Å; W256-F260 PolarHBondContact O-N 2.74Å; W256-F260 VanDerWaalsContact O-N 3.1Å; Q257-F260 CarbonylContact O-C 3.44Å; Q257-F260 PolarHBondContact O-N 3Å; F260-R262 PolarHBondContact O-N 2.98Å; F260-V263 HydrophobicContact CD1-CB 4.29Å; F260-V263 HydrophobicContact CD1-CG1 4.19Å; F260-V263 PolarHBondContact O-N 3.02Å; F260-L264 HydrophobicContact CB-CD1 4.32Å; F260-L264 WeakPolarHBondContact O-CB 3.45Å; F260-L264 WeakPolarHBondContact O-CG 3.24Å; F260-L264 PolarHBondContact O-N 3.38Å; F260-L423 HydrophobicContact CE2-CD2 4.26Å; F260-L423 HydrophobicContact CZ-CD2 4.32Å
261	Q	89.4	Confident	89.4	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-59.6	-38.2	175.8	-167.8	167.9	19.6	0	0	111.2	M45 L183 Q257 Y259 S265 S359	M45-Q261 VanDerWaalsContact O-CG 3.32Å; M45-Q261 WeakPolarHBondContact O-CG 3.48Å; M45-Q261 PolarHBondContact O-NE2 2.92Å; L183-Q261 HydrophobicContact CD1-CG 4Å; L183-Q261 HydrophobicContact CD2-CG 4.12Å; Q257-Q261 VanDerWaalsContact O-CB 3.23Å; Q257-Q261 WeakPolarHBondContact O-CB 3.44Å; Q257-Q261 PolarHBondContact O-N 3.15Å; Y259-Q261 VanDerWaalsContact C-N 3.26Å; Y259-Q261 PolarHBondContact O-N 2.69Å; Q261-S265 VanDerWaalsContact O-CB 3.3Å; Q261-S265 WeakPolarHBondContact O-CB 3.33Å; Q261-S265 PolarHBondContact O-N 3.43Å; Q261-S265 VanDerWaalsContact O-N 3.13Å; Q261-S265 PolarHBondContact O-OG 3.28Å; Q261-S359 PolarHBondContact NE2-OG 3.46Å
262	R	90.2	Very high	89.1	Confident	2 Å²	2	15.8 Å²	15.8	1%	0.008	9%	0.089	C	C	.	.	H	α-helix	trans	-74.5	-44.2	174.4	-79.6	75.1	-178.9	167.8	-2.9	111.8	T59 M60 T63 D190 V258 Y259 F260 L264 S265 A266 S352	T59-R262 HydrophobicContact CG2-CG 3.88Å; T59-R262 PolarHBondContact OG1-NE 3.16Å; M60-R262 HydrophobicContact CB-CB 4.34Å; M60-R262 HydrophobicContact CB-CG 4.35Å; M60-R262 HydrophobicContact CE-CB 3.53Å; M60-R262 HydrophobicContact CG-CB 4.42Å; T63-R262 VanDerWaalsContact OG1-CZ 3.23Å; T63-R262 PolarHBondContact OG1-NE 2.82Å; T63-R262 VanDerWaalsContact OG1-NE 3.12Å; T63-R262 PolarHBondContact OG1-NH2 2.89Å; D190-R262 IonicContact OD2-NH2 3.69Å; D190-R262 PolarHBondContact OD2-NH2 3.47Å; V258-R262 WeakPolarHBondContact O-CD 3.47Å; V258-R262 PolarHBondContact O-NH1 2.94Å; Y259-R262 PolarHBondContact O-N 3.42Å; Y259-R262 VanDerWaalsContact O-N 3.12Å; F260-R262 PolarHBondContact O-N 2.98Å; R262-L264 VanDerWaalsContact C-N 3.29Å; R262-L264 PolarHBondContact O-N 3.36Å; R262-S265 WeakPolarHBondContact CA-OG 3.35Å; R262-S265 PolarHBondContact O-N 2.82Å; R262-S265 PolarHBondContact O-OG 3.44Å; R262-A266 PolarHBondContact O-N 2.84Å; R262-S352 PolarHBondContact NH2-OG 3.47Å
263	V	89.6	Confident	89.3	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-56.4	-44.7	175.4	165.8	0	0	0	0	111.4	M60 A105 Y259 F260 S265 A266 A272	M60-V263 HydrophobicContact CE-CG2 3.81Å; A105-V263 HydrophobicContact CB-CG1 3.78Å; A105-V263 HydrophobicContact CB-CG2 4.29Å; Y259-V263 HydrophobicContact CD1-CG2 4.4Å; Y259-V263 HydrophobicContact CD2-CG2 4.1Å; Y259-V263 HydrophobicContact CE1-CG2 3.9Å; Y259-V263 HydrophobicContact CE2-CG2 3.55Å; Y259-V263 HydrophobicContact CG-CG2 4.49Å; Y259-V263 VanDerWaalsContact CZ-CG2 3.44Å; Y259-V263 PolarHBondContact O-N 2.7Å; Y259-V263 VanDerWaalsContact O-N 3.1Å; F260-V263 HydrophobicContact CD1-CB 4.29Å; F260-V263 HydrophobicContact CD1-CG1 4.19Å; F260-V263 PolarHBondContact O-N 3.02Å; V263-S265 VanDerWaalsContact C-N 3.34Å; V263-A266 WeakPolarHBondContact O-CB 3.2Å; V263-A266 PolarHBondContact O-N 3.31Å; V263-A272 HydrophobicContact CB-CB 4.49Å; V263-A272 HydrophobicContact CG1-CB 3.92Å; V263-A272 WeakPolarHBondContact O-CB 3.32Å
264	L	88.3	Confident	89.5	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-74	-26.6	-177.1	-64.7	174.2	0	0	0	112.3	V46 M108 R109 Y113 V114 F260 R262 A266	V46-L264 HydrophobicContact CG1-CB 4.16Å; M108-L264 HydrophobicContact CB-CD2 4.1Å; M108-L264 VanDerWaalsContact O-CD2 3.31Å; M108-L264 WeakPolarHBondContact O-CD2 3.18Å; R109-L264 WeakPolarHBondContact CD-O 3.34Å; R109-L264 PolarHBondContact NE-O 2.95Å; Y113-L264 WeakPolarHBondContact O-CD2 2.86Å; V114-L264 WeakPolarHBondContact O-CD1 3.37Å; F260-L264 HydrophobicContact CB-CD1 4.32Å; F260-L264 WeakPolarHBondContact O-CB 3.45Å; F260-L264 WeakPolarHBondContact O-CG 3.24Å; F260-L264 PolarHBondContact O-N 3.38Å; R262-L264 VanDerWaalsContact C-N 3.29Å; R262-L264 PolarHBondContact O-N 3.36Å; L264-A266 VanDerWaalsContact C-N 3.29Å; L264-A266 PolarHBondContact O-N 3.21Å
265	S	86.2	Confident	89.5	Confident	1 Å²	1	20.6 Å²	20.6	1%	0.007	12%	0.116	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.3	-8.3	173.3	74.8	0	0	0	0	114.9	V46 R49 I51 Q261 R262 V263	V46-S265 VanDerWaalsContact O-CA 3.27Å; V46-S265 WeakPolarHBondContact O-CA 3.07Å; V46-S265 WeakPolarHBondContact O-CB 3.34Å; R49-S265 CarbonylContact C-O 3.44Å; R49-S265 VanDerWaalsContact C-O 3.27Å; R49-S265 WeakPolarHBondContact CA-O 3.12Å; I51-S265 PolarHBondContact N-O 3.04Å; Q261-S265 VanDerWaalsContact O-CB 3.3Å; Q261-S265 WeakPolarHBondContact O-CB 3.33Å; Q261-S265 PolarHBondContact O-N 3.43Å; Q261-S265 VanDerWaalsContact O-N 3.13Å; Q261-S265 PolarHBondContact O-OG 3.28Å; R262-S265 WeakPolarHBondContact CA-OG 3.35Å; R262-S265 PolarHBondContact O-N 2.82Å; R262-S265 PolarHBondContact O-OG 3.44Å; V263-S265 VanDerWaalsContact C-N 3.34Å
266	A	86.4	Confident	89.6	Confident	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.113	C	C	.	.	B	Isolated β-bridge	trans	-68.7	151.3	177.8	0	0	0	0	0	111.5	R109 R262 V263 L264 S268 A272 L275	R109-A266 VanDerWaalsContact CZ-O 3.23Å; R109-A266 PolarHBondContact NE-O 3.06Å; R109-A266 PolarHBondContact NH2-O 3Å; R262-A266 PolarHBondContact O-N 2.84Å; V263-A266 WeakPolarHBondContact O-CB 3.2Å; V263-A266 PolarHBondContact O-N 3.31Å; L264-A266 VanDerWaalsContact C-N 3.29Å; L264-A266 PolarHBondContact O-N 3.21Å; A266-S268 VanDerWaalsContact C-N 3.34Å; A266-S268 PolarHBondContact O-N 3.02Å; A266-A272 HydrophobicContact CB-CB 3.76Å; A266-L275 HydrophobicContact CB-CD1 3.96Å
267	S	82.1	Confident	89.8	Confident	43 Å²	43	23.5 Å²	23.5	30%	0.301	13%	0.128	S	C	.	.	S	Bend	trans	-68.8	-28.9	178.4	60.6	0	0	0	0	114	R49 R109 Y271	R49-S267 WeakPolarHBondContact O-CA 3.48Å; R49-S267 PolarHBondContact O-N 3.26Å; R109-S267 PolarHBondContact NH2-O 3.39Å; S267-Y271 VanDerWaalsContact OG-CD2 3.27Å; S267-Y271 WeakPolarHBondContact OG-CD2 3.49Å
268	S	86.3	Confident	89.9	Confident	38 Å²	38	27 Å²	27	27%	0.266	15%	0.146	S	C	.	.	S	Bend	trans	-143.5	164.5	175.3	91	0	0	0	0	112.5	A266 T270 Y271 A272	A266-S268 VanDerWaalsContact C-N 3.34Å; A266-S268 PolarHBondContact O-N 3.02Å; S268-T270 VanDerWaalsContact C-N 3.31Å; S268-T270 PolarHBondContact O-N 3.06Å; S268-T270 PolarHBondContact OG-N 3.28Å; S268-Y271 PolarHBondContact O-N 3.49Å; S268-Y271 WeakPolarHBondContact OG-CD2 3.47Å; S268-Y271 PolarHBondContact OG-N 3.47Å; S268-Y271 VanDerWaalsContact OG-N 3.12Å; S268-A272 PolarHBondContact O-N 3.32Å
269	A	86.9	Confident	90	Very high	20 Å²	20	27 Å²	27	17%	0.165	15%	0.146	C	C	.	.	H	α-helix	trans	-59.2	-42.2	173.6	0	0	0	0	0	112	K106 R109 A272 Q273	K106-A269 HydrophobicContact CB-CB 4.47Å; K106-A269 HydrophobicContact CG-CB 4.1Å; R109-A269 HydrophobicContact CB-CB 4.39Å; R109-A269 HydrophobicContact CG-CB 4.4Å; A269-A272 WeakPolarHBondContact O-CB 3.43Å; A269-A272 PolarHBondContact O-N 3.09Å; A269-Q273 WeakPolarHBondContact O-CG 3.29Å; A269-Q273 PolarHBondContact O-N 3.35Å; A269-Q273 VanDerWaalsContact O-N 3.15Å
270	T	88.3	Confident	90.1	Very high	94 Å²	94	27 Å²	27	58%	0.577	15%	0.147	S	C	*	.	H	α-helix	trans	-62.9	-44.4	177.2	-49.7	0	0	0	0	111.3	S268 A272 Q273 V274	S268-T270 VanDerWaalsContact C-N 3.31Å; S268-T270 PolarHBondContact O-N 3.06Å; S268-T270 PolarHBondContact OG-N 3.28Å; T270-A272 VanDerWaalsContact C-N 3.29Å; T270-A272 PolarHBondContact O-N 3.44Å; T270-Q273 PolarHBondContact O-N 3.32Å; T270-V274 WeakPolarHBondContact O-CG2 3.37Å; T270-V274 PolarHBondContact O-N 3.22Å
271	Y	88.9	Confident	90.2	Very high	112 Å²	112	33.8 Å²	33.8	44%	0.439	18%	0.177	S	C	.	.	H	α-helix	trans	-58.8	-43.1	174.6	-78.8	-74.5	0	0	0	110.8	L53 S267 S268 Q273 V274 L275	L53-Y271 HydrophobicContact CB-CD1 4.42Å; L53-Y271 HydrophobicContact CB-CE1 4.48Å; L53-Y271 HydrophobicContact CD1-CD1 4.07Å; S267-Y271 VanDerWaalsContact OG-CD2 3.27Å; S267-Y271 WeakPolarHBondContact OG-CD2 3.49Å; S268-Y271 PolarHBondContact O-N 3.49Å; S268-Y271 WeakPolarHBondContact OG-CD2 3.47Å; S268-Y271 PolarHBondContact OG-N 3.47Å; S268-Y271 VanDerWaalsContact OG-N 3.12Å; Y271-Q273 VanDerWaalsContact C-N 3.28Å; Y271-Q273 PolarHBondContact O-N 3.06Å; Y271-V274 PolarHBondContact O-N 3.37Å; Y271-L275 WeakPolarHBondContact O-CB 3.3Å; Y271-L275 VanDerWaalsContact O-CG 3.22Å; Y271-L275 WeakPolarHBondContact O-CG 3.45Å; Y271-L275 PolarHBondContact O-N 3.27Å
272	A	89.3	Confident	90.3	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-58.6	-37.1	177.8	0	0	0	0	0	113.4	A105 R109 V263 A266 S268 A269 T270 S276	A105-A272 HydrophobicContact CB-CB 4.28Å; R109-A272 HydrophobicContact CB-CB 4.41Å; R109-A272 HydrophobicContact CG-CB 4.46Å; V263-A272 HydrophobicContact CB-CB 4.49Å; V263-A272 HydrophobicContact CG1-CB 3.92Å; V263-A272 WeakPolarHBondContact O-CB 3.32Å; A266-A272 HydrophobicContact CB-CB 3.76Å; S268-A272 PolarHBondContact O-N 3.32Å; A269-A272 WeakPolarHBondContact O-CB 3.43Å; A269-A272 PolarHBondContact O-N 3.09Å; T270-A272 VanDerWaalsContact C-N 3.29Å; T270-A272 PolarHBondContact O-N 3.44Å; A272-S276 PolarHBondContact O-N 3.2Å; A272-S276 PolarHBondContact O-OG 3.11Å
273	Q	92.8	Very high	90.4	Very high	40 Å²	40	34.4 Å²	34.4	19%	0.187	18%	0.184	C	C	.	.	H	α-helix	trans	-68.9	-47.3	174.9	-56	-170	-79.4	0	0	111.5	G101 L102 A105 K106 A269 T270 Y271 L275 S276 F277	G101-Q273 VanDerWaalsContact O-CG 3.25Å; G101-Q273 WeakPolarHBondContact O-CG 3.31Å; G101-Q273 PolarHBondContact O-NE2 3.42Å; L102-Q273 PolarHBondContact O-NE2 2.96Å; A105-Q273 HydrophobicContact CB-CG 4.21Å; K106-Q273 HydrophobicContact CB-CG 4.49Å; A269-Q273 WeakPolarHBondContact O-CG 3.29Å; A269-Q273 PolarHBondContact O-N 3.35Å; A269-Q273 VanDerWaalsContact O-N 3.15Å; T270-Q273 PolarHBondContact O-N 3.32Å; Y271-Q273 VanDerWaalsContact C-N 3.28Å; Y271-Q273 PolarHBondContact O-N 3.06Å; Q273-L275 VanDerWaalsContact C-N 3.3Å; Q273-L275 PolarHBondContact O-N 3.44Å; Q273-S276 WeakPolarHBondContact O-CB 3.38Å; Q273-S276 PolarHBondContact O-N 3.42Å; Q273-S276 VanDerWaalsContact O-N 3.07Å; Q273-F277 HydrophobicContact CB-CE2 4.13Å; Q273-F277 VanDerWaalsContact O-CD2 3.25Å; Q273-F277 WeakPolarHBondContact O-CD2 3.45Å; Q273-F277 PolarHBondContact O-N 3.12Å
274	V	92.9	Very high	90.6	Very high	62 Å²	62	37.5 Å²	37.5	38%	0.376	20%	0.2	S	C	.	.	H	α-helix	trans	-60.7	-41.7	178.8	178.2	0	0	0	0	111	L53 T270 Y271 S276 F277 L278	L53-V274 HydrophobicContact CD1-CB 4.2Å; L53-V274 HydrophobicContact CD1-CG1 3.66Å; T270-V274 WeakPolarHBondContact O-CG2 3.37Å; T270-V274 PolarHBondContact O-N 3.22Å; Y271-V274 PolarHBondContact O-N 3.37Å; V274-S276 VanDerWaalsContact C-N 3.27Å; V274-S276 PolarHBondContact O-N 2.99Å; V274-F277 PolarHBondContact O-N 3.5Å; V274-L278 WeakPolarHBondContact O-CB 3.41Å; V274-L278 PolarHBondContact O-N 3.43Å
275	L	92.3	Very high	90.9	Very high	1 Å²	1	39.6 Å²	39.6	1%	0.005	21%	0.213	C	C	.	.	H	α-helix	trans	-56.4	-43	174.2	-72.8	-177.2	0	0	0	111.6	L53 M60 A266 Y271 Q273 L278 A279	L53-L275 HydrophobicContact CD1-CD2 3.76Å; L53-L275 HydrophobicContact CD1-CG 4.31Å; L53-L275 HydrophobicContact CG-CD2 4.49Å; L53-L275 WeakPolarHBondContact O-CD2 3.29Å; M60-L275 HydrophobicContact CE-CB 3.83Å; M60-L275 HydrophobicContact SD-CB 3.99Å; A266-L275 HydrophobicContact CB-CD1 3.96Å; Y271-L275 WeakPolarHBondContact O-CB 3.3Å; Y271-L275 VanDerWaalsContact O-CG 3.22Å; Y271-L275 WeakPolarHBondContact O-CG 3.45Å; Y271-L275 PolarHBondContact O-N 3.27Å; Q273-L275 VanDerWaalsContact C-N 3.3Å; Q273-L275 PolarHBondContact O-N 3.44Å; L275-L278 PolarHBondContact O-N 2.93Å; L275-A279 VanDerWaalsContact O-CB 3.29Å; L275-A279 WeakPolarHBondContact O-CB 3.33Å; L275-A279 PolarHBondContact O-N 2.8Å
276	S	94	Very high	91.2	Very high	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-65	-41.4	179	-54.4	0	0	0	0	112.2	M60 L97 Y259 A272 Q273 V274 A279 A280	M60-S276 WeakPolarHBondContact SD-CA 3.34Å; M60-S276 PolarHBondContact SD-N 3.41Å; L97-S276 WeakPolarHBondContact O-CB 3.4Å; Y259-S276 PolarHBondContact OH-OG 3.3Å; A272-S276 PolarHBondContact O-N 3.2Å; A272-S276 PolarHBondContact O-OG 3.11Å; Q273-S276 WeakPolarHBondContact O-CB 3.38Å; Q273-S276 PolarHBondContact O-N 3.42Å; Q273-S276 VanDerWaalsContact O-N 3.07Å; V274-S276 VanDerWaalsContact C-N 3.27Å; V274-S276 PolarHBondContact O-N 2.99Å; S276-A279 PolarHBondContact O-N 3.1Å; S276-A280 WeakPolarHBondContact O-CB 3.17Å; S276-A280 PolarHBondContact O-N 3.21Å
277	F	94.9	Very high	91.5	Very high	74 Å²	74	40.1 Å²	40.1	33%	0.325	22%	0.216	S	C	.	.	H	α-helix	trans	-69.4	-41	176.5	-58.5	-41.5	0	0	0	113	V98 L102 Q273 V274 A279 A280 F281	V98-F277 HydrophobicContact CG1-CD1 4.43Å; V98-F277 HydrophobicContact CG1-CE1 4.14Å; V98-F277 HydrophobicContact CG2-CD1 4.29Å; L102-F277 HydrophobicContact CD2-CE1 4.11Å; L102-F277 HydrophobicContact CD2-CZ 3.58Å; L102-F277 HydrophobicContact CG-CE1 3.78Å; L102-F277 HydrophobicContact CG-CZ 3.71Å; Q273-F277 HydrophobicContact CB-CE2 4.13Å; Q273-F277 VanDerWaalsContact O-CD2 3.25Å; Q273-F277 WeakPolarHBondContact O-CD2 3.45Å; Q273-F277 PolarHBondContact O-N 3.12Å; V274-F277 PolarHBondContact O-N 3.5Å; F277-A279 VanDerWaalsContact C-N 3.3Å; F277-A279 PolarHBondContact O-N 3.19Å; F277-A280 PolarHBondContact O-N 2.72Å; F277-F281 PolarHBondContact O-N 3.26Å; F277-F281 VanDerWaalsContact O-N 3.12Å
278	L	93.6	Very high	92.1	Very high	76 Å²	76	40.9 Å²	40.9	40%	0.398	22%	0.218	S	C	.	.	H	α-helix	trans	-62.4	-42.3	175.9	-177.7	59.9	0	0	0	110.6	V274 L275 F281 G282	V274-L278 WeakPolarHBondContact O-CB 3.41Å; V274-L278 PolarHBondContact O-N 3.43Å; L275-L278 PolarHBondContact O-N 2.93Å; L278-F281 PolarHBondContact O-N 3.3Å; L278-G282 PolarHBondContact O-N 2.93Å
279	A	92.9	Very high	92.5	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-65.3	-40.2	176	0	0	0	0	0	112.6	M60 T61 L97 L275 S276 F277 F281 G282 C283	M60-A279 HydrophobicContact CB-CB 3.87Å; M60-A279 HydrophobicContact CG-CB 3.55Å; M60-A279 HydrophobicContact SD-CB 3.9Å; T61-A279 WeakPolarHBondContact OG1-CA 3.29Å; L97-A279 HydrophobicContact CD1-CB 3.9Å; L97-A279 HydrophobicContact CD2-CB 4.44Å; L275-A279 VanDerWaalsContact O-CB 3.29Å; L275-A279 WeakPolarHBondContact O-CB 3.33Å; L275-A279 PolarHBondContact O-N 2.8Å; S276-A279 PolarHBondContact O-N 3.1Å; F277-A279 VanDerWaalsContact C-N 3.3Å; F277-A279 PolarHBondContact O-N 3.19Å; A279-F281 VanDerWaalsContact C-N 3.33Å; A279-F281 PolarHBondContact O-N 3.44Å; A279-G282 PolarHBondContact O-N 2.87Å; A279-C283 PolarHBondContact O-N 2.9Å; A279-C283 PolarHBondContact O-SG 3.03Å
280	A	94.6	Very high	92.8	Very high	5 Å²	5	38.1 Å²	38.1	4%	0.041	20%	0.198	C	C	.	.	H	α-helix	trans	-58.4	-45.8	176.1	0	0	0	0	0	112.1	A94 L97 V98 S276 F277 L284	A94-A280 HydrophobicContact CB-CB 4.46Å; A94-A280 VanDerWaalsContact O-CB 3.32Å; A94-A280 WeakPolarHBondContact O-CB 3.23Å; L97-A280 HydrophobicContact CB-CB 3.81Å; L97-A280 HydrophobicContact CD1-CB 4.45Å; V98-A280 HydrophobicContact CG2-CB 3.64Å; S276-A280 WeakPolarHBondContact O-CB 3.17Å; S276-A280 PolarHBondContact O-N 3.21Å; F277-A280 PolarHBondContact O-N 2.72Å; A280-L284 PolarHBondContact O-N 3.33Å
281	F	94.4	Very high	93.1	Very high	142 Å²	142	34.8 Å²	34.8	62%	0.623	18%	0.178	S	C	*	.	H	α-helix	trans	-64.9	-44.6	174.6	179	-102.5	0	0	0	111.6	F277 L278 A279 C283 L284 V285	F277-F281 PolarHBondContact O-N 3.26Å; F277-F281 VanDerWaalsContact O-N 3.12Å; L278-F281 PolarHBondContact O-N 3.3Å; A279-F281 VanDerWaalsContact C-N 3.33Å; A279-F281 PolarHBondContact O-N 3.44Å; F281-C283 PolarHBondContact O-N 2.94Å; F281-L284 PolarHBondContact O-N 3.21Å; F281-V285 HydrophobicContact CD1-CG2 4.2Å; F281-V285 HydrophobicContact CE1-CG2 3.72Å; F281-V285 HydrophobicContact CE2-CG2 4.14Å; F281-V285 HydrophobicContact CZ-CG2 3.69Å; F281-V285 WeakPolarHBondContact O-CG2 3.37Å; F281-V285 PolarHBondContact O-N 3.39Å; F281-V285 VanDerWaalsContact O-N 3.1Å
282	G	92.1	Very high	93.4	Very high	15 Å²	15	31.4 Å²	31.4	16%	0.155	17%	0.167	C	C	.	.	H	α-helix	trans	-55.7	-47.3	176.7	0	0	0	0	0	112.4	L278 A279 L284 V285 M286	L278-G282 PolarHBondContact O-N 2.93Å; A279-G282 PolarHBondContact O-N 2.87Å; G282-L284 PolarHBondContact O-N 2.68Å; G282-V285 PolarHBondContact O-N 2.66Å; G282-M286 WeakPolarHBondContact O-CB 3.32Å; G282-M286 WeakPolarHBondContact O-CG 3.33Å; G282-M286 PolarHBondContact O-N 2.98Å
283	C	92.1	Very high	93.7	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-56.6	-47	177.4	-70.9	0	0	0	0	112	V65 Y69 A279 F281 V285 M286 A287	V65-C283 HydrophobicContact CG2-CB 4.39Å; Y69-C283 PolarHBondContact OH-O 3.07Å; A279-C283 PolarHBondContact O-N 2.9Å; A279-C283 PolarHBondContact O-SG 3.03Å; F281-C283 PolarHBondContact O-N 2.94Å; C283-V285 PolarHBondContact O-N 2.69Å; C283-M286 PolarHBondContact O-N 3.06Å; C283-A287 PolarHBondContact O-N 3.07Å
284	L	94	Very high	93.8	Very high	65 Å²	65	29.5 Å²	29.5	34%	0.34	16%	0.158	S	C	.	.	H	α-helix	trans	-61.4	-44.7	178.5	-68.6	176.1	0	0	0	112.3	P90 F91 A94 A280 F281 G282 M286 A287 V288	P90-L284 HydrophobicContact CB-CD2 4.47Å; F91-L284 HydrophobicContact CD1-CD2 4.07Å; F91-L284 HydrophobicContact CE1-CD2 4.35Å; A94-L284 HydrophobicContact CB-CD1 4.12Å; A94-L284 HydrophobicContact CB-CD2 3.76Å; A94-L284 HydrophobicContact CB-CG 3.68Å; A280-L284 PolarHBondContact O-N 3.33Å; F281-L284 PolarHBondContact O-N 3.21Å; G282-L284 PolarHBondContact O-N 2.68Å; L284-M286 VanDerWaalsContact C-N 3.3Å; L284-M286 PolarHBondContact O-N 2.71Å; L284-A287 PolarHBondContact O-N 2.66Å; L284-V288 PolarHBondContact O-N 3.14Å
285	V	94.2	Very high	93.9	Very high	44 Å²	44	26.6 Å²	26.6	27%	0.267	14%	0.14	S	C	.	.	H	α-helix	trans	-62.1	-40.9	177.7	173.1	0	0	0	0	111.1	F198 F281 G282 C283 A287 V288 P289	F198-V285 HydrophobicContact CE2-CG1 4.03Å; F281-V285 HydrophobicContact CD1-CG2 4.2Å; F281-V285 HydrophobicContact CE1-CG2 3.72Å; F281-V285 HydrophobicContact CE2-CG2 4.14Å; F281-V285 HydrophobicContact CZ-CG2 3.69Å; F281-V285 WeakPolarHBondContact O-CG2 3.37Å; F281-V285 PolarHBondContact O-N 3.39Å; F281-V285 VanDerWaalsContact O-N 3.1Å; G282-V285 PolarHBondContact O-N 2.66Å; C283-V285 PolarHBondContact O-N 2.69Å; V285-A287 VanDerWaalsContact C-N 3.32Å; V285-A287 PolarHBondContact O-N 2.77Å; V285-V288 PolarHBondContact O-N 3.37Å; V285-P289 WeakPolarHBondContact O-CD 3.32Å
286	M	91.5	Very high	94	Very high	7 Å²	7	26.5 Å²	26.5	3%	0.034	14%	0.14	C	C	.	.	H	α-helix	trans	-72.9	-23.3	-179.7	-66.5	-60.3	-63.6	0	0	113.4	T61 V65 L194 I197 F198 G282 C283 L284 P289	T61-M286 HydrophobicContact CG2-CG 4.44Å; V65-M286 HydrophobicContact CB-CB 4.46Å; V65-M286 HydrophobicContact CG1-CB 3.73Å; V65-M286 HydrophobicContact CG1-CE 4.04Å; V65-M286 HydrophobicContact CG1-CG 4.17Å; V65-M286 HydrophobicContact CG2-CB 3.78Å; V65-M286 HydrophobicContact CG2-CG 4.09Å; L194-M286 HydrophobicContact CD1-CE 3.85Å; L194-M286 HydrophobicContact CD1-CG 4.27Å; L194-M286 HydrophobicContact CD1-SD 4.31Å; I197-M286 HydrophobicContact CB-CE 3.7Å; I197-M286 HydrophobicContact CG2-CE 3.27Å; F198-M286 HydrophobicContact CB-CE 4.09Å; F198-M286 HydrophobicContact CB-SD 3.9Å; F198-M286 HydrophobicContact CD2-SD 3.62Å; F198-M286 HydrophobicContact CG-SD 4.25Å; G282-M286 WeakPolarHBondContact O-CB 3.32Å; G282-M286 WeakPolarHBondContact O-CG 3.33Å; G282-M286 PolarHBondContact O-N 2.98Å; C283-M286 PolarHBondContact O-N 3.06Å; L284-M286 VanDerWaalsContact C-N 3.3Å; L284-M286 PolarHBondContact O-N 2.71Å; M286-P289 WeakPolarHBondContact O-CD 3.43Å; M286-P289 WeakPolarHBondContact O-CG 3.29Å
287	A	92.5	Very high	94	Very high	4 Å²	4	26.5 Å²	26.5	3%	0.033	14%	0.14	C	C	.	.	H	α-helix	trans	-75.7	-26.6	175.9	0	0	0	0	0	113.7	Y69 P90 C283 L284 V285 S290 V291	Y69-A287 HydrophobicContact CE1-CB 3.89Å; P90-A287 HydrophobicContact CB-CB 3.54Å; P90-A287 HydrophobicContact CG-CB 3.6Å; C283-A287 PolarHBondContact O-N 3.07Å; L284-A287 PolarHBondContact O-N 2.66Å; V285-A287 VanDerWaalsContact C-N 3.32Å; V285-A287 PolarHBondContact O-N 2.77Å; A287-S290 WeakPolarHBondContact O-CB 3.41Å; A287-S290 PolarHBondContact O-N 3.49Å; A287-S290 VanDerWaalsContact O-N 3.15Å; A287-V291 WeakPolarHBondContact O-CG2 3.49Å; A287-V291 PolarHBondContact O-N 3.35Å
288	V	95	Very high	93.8	Very high	59 Å²	59	23.2 Å²	23.2	36%	0.358	13%	0.127	S	C	.	.	H	α-helix	trans	-52.2	-53.8	-179	177	0	0	0	0	112.7	W202 L284 V285 S290 V291 L292	W202-V288 HydrophobicContact CH2-CB 4.1Å; W202-V288 HydrophobicContact CH2-CG1 3.63Å; W202-V288 HydrophobicContact CZ2-CB 3.9Å; W202-V288 HydrophobicContact CZ2-CG1 3.97Å; W202-V288 HydrophobicContact CZ3-CG1 4.47Å; L284-V288 PolarHBondContact O-N 3.14Å; V285-V288 PolarHBondContact O-N 3.37Å; V288-S290 VanDerWaalsContact C-N 3.28Å; V288-S290 PolarHBondContact O-N 3.04Å; V288-V291 PolarHBondContact O-N 2.78Å; V288-L292 HydrophobicContact CG1-CD1 3.96Å; V288-L292 HydrophobicContact CG1-CG 4.36Å; V288-L292 WeakPolarHBondContact O-CG 3.46Å; V288-L292 PolarHBondContact O-N 2.89Å
289	P	94.6	Very high	93.8	Very high	1 Å²	1	19.6 Å²	19.6	1%	0.006	11%	0.108	C	C	.	.	H	α-helix	trans	-64	-33.1	-179.4	26.5	-36.9	0	0	0	112.6	L201 V205 V285 M286 L292 I293	L201-P289 HydrophobicContact CB-CB 3.78Å; L201-P289 HydrophobicContact CB-CG 3.93Å; L201-P289 HydrophobicContact CD1-CG 4.41Å; V205-P289 HydrophobicContact CG2-CB 3.9Å; V285-P289 WeakPolarHBondContact O-CD 3.32Å; M286-P289 WeakPolarHBondContact O-CD 3.43Å; M286-P289 WeakPolarHBondContact O-CG 3.29Å; P289-L292 PolarHBondContact O-N 2.9Å; P289-I293 WeakPolarHBondContact O-CB 3.44Å; P289-I293 WeakPolarHBondContact O-CD1 3.31Å; P289-I293 VanDerWaalsContact O-CG1 3.24Å; P289-I293 WeakPolarHBondContact O-CG1 3.3Å; P289-I293 PolarHBondContact O-N 3.41Å
290	S	93.1	Very high	93.8	Very high	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64	-43.3	174.5	-52	0	0	0	0	112.3	I70 A74 A287 V288 I293 G294	I70-S290 WeakPolarHBondContact CG2-OG 3.45Å; I70-S290 WeakPolarHBondContact O-CB 3.47Å; A74-S290 WeakPolarHBondContact CB-O 3.47Å; A287-S290 WeakPolarHBondContact O-CB 3.41Å; A287-S290 PolarHBondContact O-N 3.49Å; A287-S290 VanDerWaalsContact O-N 3.15Å; V288-S290 VanDerWaalsContact C-N 3.28Å; V288-S290 PolarHBondContact O-N 3.04Å; S290-I293 PolarHBondContact O-N 3.44Å; S290-G294 PolarHBondContact O-N 3.4Å
291	V	95.1	Very high	93.6	Very high	24 Å²	24	21.3 Å²	21.3	15%	0.145	12%	0.116	C	C	.	.	H	α-helix	trans	-60.8	-46.2	174.1	169.1	0	0	0	0	110.6	T73 V77 L84 A287 V288 I293 G294 A295	T73-V291 HydrophobicContact CG2-CG2 3.48Å; T73-V291 VanDerWaalsContact CG2-CG2 3.48Å; V77-V291 HydrophobicContact CG2-CB 4.44Å; V77-V291 HydrophobicContact CG2-CG1 4.17Å; V77-V291 HydrophobicContact CG2-CG2 4.27Å; L84-V291 HydrophobicContact CD1-CG1 3.73Å; L84-V291 HydrophobicContact CD1-CG2 3.99Å; A287-V291 WeakPolarHBondContact O-CG2 3.49Å; A287-V291 PolarHBondContact O-N 3.35Å; V288-V291 PolarHBondContact O-N 2.78Å; V291-I293 VanDerWaalsContact C-N 3.34Å; V291-I293 PolarHBondContact O-N 3.06Å; V291-G294 PolarHBondContact O-N 3.42Å; V291-A295 WeakPolarHBondContact O-CB 3.47Å; V291-A295 PolarHBondContact O-N 3.13Å
292	L	96	Very high	93.4	Very high	41 Å²	41	15.1 Å²	15.1	22%	0.215	9%	0.089	C	C	.	.	H	α-helix	trans	-63	-41.1	178.9	-66.8	175.7	0	0	0	111.5	V205 I217 V288 P289 A295 I296	V205-L292 HydrophobicContact CG1-CB 4.17Å; V205-L292 HydrophobicContact CG1-CD1 3.81Å; V205-L292 HydrophobicContact CG2-CB 4.17Å; V205-L292 HydrophobicContact CG2-CD1 4.46Å; I217-L292 HydrophobicContact CD1-CD2 4.1Å; V288-L292 HydrophobicContact CG1-CD1 3.96Å; V288-L292 HydrophobicContact CG1-CG 4.36Å; V288-L292 WeakPolarHBondContact O-CG 3.46Å; V288-L292 PolarHBondContact O-N 2.89Å; P289-L292 PolarHBondContact O-N 2.9Å; L292-A295 PolarHBondContact O-N 3.21Å; L292-I296 WeakPolarHBondContact O-CB 3.3Å; L292-I296 WeakPolarHBondContact O-CD1 3.38Å; L292-I296 WeakPolarHBondContact O-CG1 3.28Å; L292-I296 PolarHBondContact O-N 2.91Å
293	I	95.1	Very high	93.2	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-63.6	-43.9	176	-72	164.1	0	0	0	111.5	L201 V205 P289 S290 V291 A295 I296 G297 L322 V325 L326	L201-I293 HydrophobicContact CD2-CD1 4.1Å; V205-I293 HydrophobicContact CG2-CD1 4.49Å; V205-I293 HydrophobicContact CG2-CG1 4.16Å; P289-I293 WeakPolarHBondContact O-CB 3.44Å; P289-I293 WeakPolarHBondContact O-CD1 3.31Å; P289-I293 VanDerWaalsContact O-CG1 3.24Å; P289-I293 WeakPolarHBondContact O-CG1 3.3Å; P289-I293 PolarHBondContact O-N 3.41Å; S290-I293 PolarHBondContact O-N 3.44Å; V291-I293 VanDerWaalsContact C-N 3.34Å; V291-I293 PolarHBondContact O-N 3.06Å; I293-A295 VanDerWaalsContact C-N 3.33Å; I293-A295 PolarHBondContact O-N 2.74Å; I293-I296 WeakPolarHBondContact O-CB 3.24Å; I293-I296 PolarHBondContact O-N 3.47Å; I293-G297 PolarHBondContact O-N 2.64Å; I293-L322 HydrophobicContact CD1-CD1 4.49Å; I293-L322 HydrophobicContact CD1-CG 4.33Å; I293-L322 HydrophobicContact CG2-CB 4.2Å; I293-L322 HydrophobicContact CG2-CG 3.87Å; I293-V325 HydrophobicContact CG2-CB 3.85Å; I293-V325 HydrophobicContact CG2-CG1 3.74Å; I293-V325 HydrophobicContact CG2-CG2 4.24Å; I293-L326 HydrophobicContact CD1-CD2 4.29Å
294	G	93.9	Very high	92.9	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-60.1	-42.8	173.7	0	0	0	0	0	112.4	A74 S290 V291 I296 G297 A298	A74-G294 WeakPolarHBondContact O-CA 3.41Å; S290-G294 PolarHBondContact O-N 3.4Å; V291-G294 PolarHBondContact O-N 3.42Å; G294-I296 PolarHBondContact O-N 3.31Å; G294-G297 PolarHBondContact O-N 3.44Å; G294-A298 PolarHBondContact O-N 3.23Å
295	A	95	Very high	92.6	Very high	0 Å²	0	22.5 Å²	22.5	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-64.6	-37.9	176.1	0	0	0	0	0	112.3	V77 W230 V291 L292 I293 A298 S299	V77-A295 HydrophobicContact CG1-CB 4.07Å; W230-A295 HydrophobicContact CD2-CB 3.57Å; W230-A295 HydrophobicContact CE3-CB 3.85Å; W230-A295 HydrophobicContact CG-CB 3.92Å; W230-A295 HydrophobicContact CH2-CB 4.46Å; W230-A295 HydrophobicContact CZ2-CB 4.2Å; W230-A295 HydrophobicContact CZ3-CB 4.28Å; V291-A295 WeakPolarHBondContact O-CB 3.47Å; V291-A295 PolarHBondContact O-N 3.13Å; L292-A295 PolarHBondContact O-N 3.21Å; I293-A295 VanDerWaalsContact C-N 3.33Å; I293-A295 PolarHBondContact O-N 2.74Å; A295-A298 PolarHBondContact O-N 3.27Å; A295-S299 VanDerWaalsContact O-CB 3.31Å; A295-S299 WeakPolarHBondContact O-CB 3.27Å; A295-S299 PolarHBondContact O-N 2.8Å; A295-S299 PolarHBondContact O-OG 3.32Å
296	I	95.2	Very high	92.1	Very high	0 Å²	0	26 Å²	26	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-62.3	-48.9	173.2	-70.5	161.3	0	0	0	109.8	A208 L209 V214 I217 L292 I293 G294 A298 S299 T300 V325 L329	A208-I296 HydrophobicContact CB-CD1 3.83Å; A208-I296 HydrophobicContact CB-CG2 4.25Å; L209-I296 HydrophobicContact CD2-CD1 3.87Å; L209-I296 HydrophobicContact CD2-CG1 3.6Å; L209-I296 HydrophobicContact CG-CD1 3.72Å; L209-I296 HydrophobicContact CG-CG1 4.05Å; V214-I296 HydrophobicContact CG1-CG2 4.03Å; V214-I296 HydrophobicContact CG2-CG2 3.9Å; I217-I296 HydrophobicContact CG2-CG1 4.27Å; L292-I296 WeakPolarHBondContact O-CB 3.3Å; L292-I296 WeakPolarHBondContact O-CD1 3.38Å; L292-I296 WeakPolarHBondContact O-CG1 3.28Å; L292-I296 PolarHBondContact O-N 2.91Å; I293-I296 WeakPolarHBondContact O-CB 3.24Å; I293-I296 PolarHBondContact O-N 3.47Å; G294-I296 PolarHBondContact O-N 3.31Å; I296-A298 PolarHBondContact O-N 3.46Å; I296-S299 CarbonylContact O-C 3.42Å; I296-S299 WeakPolarHBondContact O-CA 3.44Å; I296-S299 PolarHBondContact O-N 3.12Å; I296-T300 PolarHBondContact O-N 2.98Å; I296-T300 PolarHBondContact O-OG1 3.42Å; I296-V325 HydrophobicContact CG2-CG1 4.16Å; I296-L329 HydrophobicContact CG2-CD1 3.72Å
297	G	93.4	Very high	91.7	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-56.9	-38.8	176.9	0	0	0	0	0	112.6	Y78 I293 G294 S299 T300 W302	Y78-G297 VanDerWaalsContact CD2-C 3.49Å; Y78-G297 WeakPolarHBondContact CE2-O 3.07Å; I293-G297 PolarHBondContact O-N 2.64Å; G294-G297 PolarHBondContact O-N 3.44Å; G297-S299 VanDerWaalsContact C-N 3.29Å; G297-S299 PolarHBondContact O-N 2.56Å; G297-T300 PolarHBondContact O-N 3.02Å; G297-W302 PolarHBondContact O-NE1 3.42Å; G297-W302 VanDerWaalsContact O-NE1 3.11Å
298	A	92.4	Very high	91.2	Very high	5 Å²	5	27.9 Å²	27.9	4%	0.041	16%	0.156	C	C	.	.	H	α-helix	trans	-69.3	-27.1	175.6	0	0	0	0	0	113.4	Y78 Q227 W230 G294 A295 I296	Y78-A298 HydrophobicContact CD2-CB 4.26Å; Q227-A298 HydrophobicContact CG-CB 4.47Å; Q227-A298 WeakPolarHBondContact CG-O 3.44Å; Q227-A298 VanDerWaalsContact NE2-CA 3.27Å; W230-A298 HydrophobicContact CB-CB 3.84Å; G294-A298 PolarHBondContact O-N 3.23Å; A295-A298 PolarHBondContact O-N 3.27Å; I296-A298 PolarHBondContact O-N 3.46Å
299	S	93.3	Very high	90.4	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.176	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.4	5.9	-177.1	-51	0	0	0	0	113	A215 S220 Y226 A295 I296 G297	A215-S299 PolarHBondContact N-O 3.49Å; S220-S299 WeakPolarHBondContact CB-OG 3.49Å; S220-S299 PolarHBondContact OG-OG 2.81Å; Y226-S299 WeakPolarHBondContact CD2-O 3.36Å; Y226-S299 VanDerWaalsContact CE2-O 3.26Å; Y226-S299 WeakPolarHBondContact CE2-O 3.32Å; A295-S299 VanDerWaalsContact O-CB 3.31Å; A295-S299 WeakPolarHBondContact O-CB 3.27Å; A295-S299 PolarHBondContact O-N 2.8Å; A295-S299 PolarHBondContact O-OG 3.32Å; I296-S299 CarbonylContact O-C 3.42Å; I296-S299 WeakPolarHBondContact O-CA 3.44Å; I296-S299 PolarHBondContact O-N 3.12Å; G297-S299 VanDerWaalsContact C-N 3.29Å; G297-S299 PolarHBondContact O-N 2.56Å
300	T	92.6	Very high	89.8	Confident	3 Å²	3	37.9 Å²	37.9	2%	0.018	20%	0.197	C	C	.	.	B	Isolated β-bridge	trans	-95.5	132.9	-175.4	-61.7	0	0	0	0	111.4	A213 I296 G297 W302 T305 L329	A213-T300 HydrophobicContact CB-CG2 4.35Å; I296-T300 PolarHBondContact O-N 2.98Å; I296-T300 PolarHBondContact O-OG1 3.42Å; G297-T300 PolarHBondContact O-N 3.02Å; T300-W302 HydrophobicContact CG2-CD2 4.04Å; T300-W302 HydrophobicContact CG2-CE3 4.26Å; T300-W302 HydrophobicContact CG2-CG 4.42Å; T300-W302 HydrophobicContact CG2-CZ2 4.38Å; T300-W302 PolarHBondContact O-N 3.21Å; T300-T305 HydrophobicContact CG2-CG2 3.65Å; T300-L329 HydrophobicContact CG2-CD1 4.01Å; T300-L329 HydrophobicContact CG2-CD2 3.94Å; T300-L329 WeakPolarHBondContact OG1-CD1 3.35Å
301	N	90.8	Very high	89.4	Confident	38 Å²	38	38.6 Å²	38.6	20%	0.203	20%	0.202	C	C	.	.			trans	-80.4	89.1	164	-168.1	-16.4	0	0	0	110.2	A213 Y226 N303 Q304	A213-N301 PolarHBondContact O-N 3.31Å; Y226-N301 HydrophobicContact CD1-CB 4.26Å; Y226-N301 HydrophobicContact CE1-CB 3.74Å; Y226-N301 HydrophobicContact CE2-CB 4.02Å; N301-N303 PolarHBondContact O-N 2.91Å; N301-N303 VanDerWaalsContact O-N 3.08Å; N301-N303 WeakPolarHBondContact OD1-CB 3.16Å; N301-N303 PolarHBondContact OD1-N 2.97Å; N301-Q304 HydrophobicContact CB-CG 4.34Å; N301-Q304 PolarHBondContact ND2-NE2 3.35Å; N301-Q304 PolarHBondContact O-N 3.27Å
302	W	90.1	Very high	88.9	Confident	12 Å²	12	37.4 Å²	37.4	5%	0.045	20%	0.195	C	C	.	.	G	3₁₀ helix	trans	-55	-30.4	-175.6	-68.2	100.7	0	0	0	114.2	G297 T300 Q304 T305 Y307 G308 A311 P312 I321 I324 V325 L329	G297-W302 PolarHBondContact O-NE1 3.42Å; G297-W302 VanDerWaalsContact O-NE1 3.11Å; T300-W302 HydrophobicContact CG2-CD2 4.04Å; T300-W302 HydrophobicContact CG2-CE3 4.26Å; T300-W302 HydrophobicContact CG2-CG 4.42Å; T300-W302 HydrophobicContact CG2-CZ2 4.38Å; T300-W302 PolarHBondContact O-N 3.21Å; W302-Q304 PolarHBondContact O-N 3.15Å; W302-T305 HydrophobicContact CE3-CG2 4.32Å; W302-T305 WeakPolarHBondContact O-CB 3.24Å; W302-T305 PolarHBondContact O-N 2.96Å; W302-T305 PolarHBondContact O-OG1 3.33Å; W302-Y307 HydrophobicContact CE3-CD1 4.06Å; W302-Y307 HydrophobicContact CE3-CG 4.16Å; W302-Y307 HydrophobicContact CZ3-CG 4.43Å; W302-G308 CarbonylContact C-O 3.41Å; W302-A311 HydrophobicContact CB-CB 4.22Å; W302-A311 HydrophobicContact CG-CB 4.07Å; W302-P312 VanDerWaalsContact CD2-CD 3.46Å; W302-P312 HydrophobicContact CD2-CG 3.94Å; W302-P312 HydrophobicContact CE3-CG 4.14Å; W302-P312 HydrophobicContact CH2-CG 4.13Å; W302-P312 HydrophobicContact CZ2-CG 3.94Å; W302-P312 HydrophobicContact CZ3-CG 4.23Å; W302-I321 HydrophobicContact CH2-CD1 4Å; W302-I321 HydrophobicContact CZ2-CD1 3.52Å; W302-I324 HydrophobicContact CH2-CG2 3.62Å; W302-I324 HydrophobicContact CZ3-CG2 3.53Å; W302-V325 HydrophobicContact CH2-CG2 3.93Å; W302-V325 HydrophobicContact CZ2-CG2 4.31Å; W302-L329 HydrophobicContact CH2-CD1 4.49Å
303	N	87.5	Confident	88.3	Confident	88 Å²	88	38.2 Å²	38.2	47%	0.471	20%	0.197	S	C	.	.	G	3₁₀ helix	trans	-60.1	-28.5	176	-173.6	7.1	0	0	0	113.1	N301 T305 Y309	N301-N303 PolarHBondContact O-N 2.91Å; N301-N303 VanDerWaalsContact O-N 3.08Å; N301-N303 WeakPolarHBondContact OD1-CB 3.16Å; N301-N303 PolarHBondContact OD1-N 2.97Å; N303-T305 VanDerWaalsContact C-N 3.32Å; N303-Y309 WeakPolarHBondContact OD1-CD1 3.4Å; N303-Y309 VanDerWaalsContact OD1-CE1 3.28Å; N303-Y309 WeakPolarHBondContact OD1-CE1 3.42Å
304	Q	85.9	Confident	87.7	Confident	127 Å²	127	41.2 Å²	41.2	59%	0.593	21%	0.213	S	C	*	.	G	3₁₀ helix	trans	-88.8	0.2	179.1	-62.8	-177.8	-3.7	0	0	113.3	A213 N301 W302	A213-Q304 HydrophobicContact CB-CB 4.14Å; N301-Q304 HydrophobicContact CB-CG 4.34Å; N301-Q304 PolarHBondContact ND2-NE2 3.35Å; N301-Q304 PolarHBondContact O-N 3.27Å; W302-Q304 PolarHBondContact O-N 3.15Å
305	T	88.3	Confident	87	Confident	19 Å²	19	44.2 Å²	44.2	12%	0.117	23%	0.226	C	C	.	.	S	Bend	trans	-101.3	168.2	-176.7	74.1	0	0	0	0	111.7	A213 T300 W302 N303 Y307 L329	A213-T305 HydrophobicContact CB-CG2 3.8Å; T300-T305 HydrophobicContact CG2-CG2 3.65Å; W302-T305 HydrophobicContact CE3-CG2 4.32Å; W302-T305 WeakPolarHBondContact O-CB 3.24Å; W302-T305 PolarHBondContact O-N 2.96Å; W302-T305 PolarHBondContact O-OG1 3.33Å; N303-T305 VanDerWaalsContact C-N 3.32Å; T305-Y307 PolarHBondContact O-N 2.87Å; T305-Y307 WeakPolarHBondContact OG1-CB 3.31Å; T305-Y307 PolarHBondContact OG1-N 3.49Å; T305-L329 HydrophobicContact CG2-CD2 3.67Å
306	T	83.4	Confident	86.2	Confident	117 Å²	117	48.4 Å²	48.4	72%	0.718	25%	0.246	S	C	*	.	T	Hydrogen-bonded Turn	trans	-71	-7.5	173.6	50.9	0	0	0	0	113.8	H328	T306-H328 PolarHBondContact OG1-ND1 3.44Å
307	Y	83.6	Confident	85.6	Confident	28 Å²	28	51.2 Å²	51.2	11%	0.11	26%	0.258	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.3	-33.5	177.9	-178.1	-100.3	0	0	0	112.8	W302 T305 V310 P312 K315 E317 I324 H328	W302-Y307 HydrophobicContact CE3-CD1 4.06Å; W302-Y307 HydrophobicContact CE3-CG 4.16Å; W302-Y307 HydrophobicContact CZ3-CG 4.43Å; T305-Y307 PolarHBondContact O-N 2.87Å; T305-Y307 WeakPolarHBondContact OG1-CB 3.31Å; T305-Y307 PolarHBondContact OG1-N 3.49Å; Y307-V310 VanDerWaalsContact CE1-O 3.26Å; Y307-V310 WeakPolarHBondContact CE1-O 3.49Å; Y307-P312 HydrophobicContact CD1-CG 4.19Å; Y307-P312 HydrophobicContact CE1-CB 4.31Å; Y307-P312 HydrophobicContact CE1-CG 3.62Å; Y307-P312 HydrophobicContact CE2-CG 4.47Å; Y307-P312 WeakPolarHBondContact OH-CA 3.24Å; Y307-K315 HydrophobicContact CE1-CD 4.35Å; Y307-E317 PolarHBondContact OH-OE2 3.43Å; Y307-I324 HydrophobicContact CD2-CG2 3.75Å; Y307-I324 HydrophobicContact CE2-CD1 3.85Å; Y307-I324 HydrophobicContact CE2-CG1 4.14Å; Y307-I324 HydrophobicContact CE2-CG2 3.88Å; Y307-I324 HydrophobicContact CG-CG2 4.33Å; Y307-H328 AromaticContact CD2-CD2 3.72Å; Y307-H328 AromaticContact CD2-NE2 3.57Å; Y307-H328 PolarHBondContact N-ND1 2.97Å
308	G	81.6	Confident	85.1	Confident	23 Å²	23	51.7 Å²	51.7	24%	0.237	26%	0.262	C	S	.	.			trans	115.2	-174.5	174.1	0	0	0	0	0	115.2	W302 V310	W302-G308 CarbonylContact C-O 3.41Å; G308-V310 PolarHBondContact O-N 3.13Å
309	Y	77.5	Confident	84.3	Confident	200 Å²	200	53.9 Å²	53.9	78%	0.784	27%	0.273	S	S	*	.	S	Bend	trans	-69.5	-26.1	-166.6	-61.7	-80.7	0	0	0	115.6	N303	N303-Y309 WeakPolarHBondContact OD1-CD1 3.4Å; N303-Y309 VanDerWaalsContact OD1-CE1 3.28Å; N303-Y309 WeakPolarHBondContact OD1-CE1 3.42Å
310	V	81.7	Confident	83.8	Confident	71 Å²	71	55.5 Å²	55.5	43%	0.43	28%	0.281	S	S	.	.	S	Bend	trans	-103	125.4	-176.4	-177.9	0	0	0	0	108.3	Y307 G308 D314 K315	Y307-V310 VanDerWaalsContact CE1-O 3.26Å; Y307-V310 WeakPolarHBondContact CE1-O 3.49Å; G308-V310 PolarHBondContact O-N 3.13Å; V310-D314 HydrophobicContact CG1-CB 3.69Å; V310-K315 HydrophobicContact CB-CG 4.35Å; V310-K315 HydrophobicContact CG1-CG 3.8Å
311	A	84.3	Confident	83.6	Confident	14 Å²	14	55.3 Å²	55.3	12%	0.116	28%	0.28	C	S	.	.			trans	-67.3	153.6	-177	0	0	0	0	0	111.7	W302 K313 D314 K315	W302-A311 HydrophobicContact CB-CB 4.22Å; W302-A311 HydrophobicContact CG-CB 4.07Å; A311-K313 HydrophobicContact CB-CG 4.18Å; A311-K313 PolarHBondContact O-N 3.47Å; A311-D314 PolarHBondContact O-N 2.9Å; A311-K315 PolarHBondContact O-N 2.79Å
312	P	85.6	Confident	83.6	Confident	0 Å²	0	53.5 Å²	53.5	0%	0	27%	0.27	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.5	-29.5	179.8	-26.4	32.5	0	0	0	114.5	Y78 W302 Y307 K315 E316 E317 I321 I324	Y78-P312 HydrophobicContact CE1-CB 4.37Å; Y78-P312 WeakPolarHBondContact OH-CD 3.33Å; W302-P312 VanDerWaalsContact CD2-CD 3.46Å; W302-P312 HydrophobicContact CD2-CG 3.94Å; W302-P312 HydrophobicContact CE3-CG 4.14Å; W302-P312 HydrophobicContact CH2-CG 4.13Å; W302-P312 HydrophobicContact CZ2-CG 3.94Å; W302-P312 HydrophobicContact CZ3-CG 4.23Å; Y307-P312 HydrophobicContact CD1-CG 4.19Å; Y307-P312 HydrophobicContact CE1-CB 4.31Å; Y307-P312 HydrophobicContact CE1-CG 3.62Å; Y307-P312 HydrophobicContact CE2-CG 4.47Å; Y307-P312 WeakPolarHBondContact OH-CA 3.24Å; P312-K315 PolarHBondContact O-N 2.61Å; P312-E316 PolarHBondContact O-N 3.23Å; P312-E317 HydrophobicContact CB-CB 4.45Å; P312-E317 PolarHBondContact O-N 3.14Å; P312-I321 HydrophobicContact CB-CD1 4.15Å; P312-I321 HydrophobicContact CG-CD1 3.99Å; P312-I324 HydrophobicContact CB-CD1 4.07Å; P312-I324 HydrophobicContact CG-CD1 4.25Å; P312-I324 HydrophobicContact CG-CG2 4.08Å
313	K	82.3	Confident	83.5	Confident	58 Å²	58	53 Å²	53	25%	0.252	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.1	-38.5	179.6	66.6	-175.6	-177.3	-174.1	0	112.5	Y78 P80 A311 K315 E316 S318	Y78-K313 HydrophobicContact CE1-CB 3.82Å; Y78-K313 WeakPolarHBondContact OH-CB 3.19Å; Y78-K313 PolarHBondContact OH-N 3.44Å; P80-K313 HydrophobicContact CG-CD 4.19Å; A311-K313 HydrophobicContact CB-CG 4.18Å; A311-K313 PolarHBondContact O-N 3.47Å; K313-K315 PolarHBondContact O-N 2.93Å; K313-E316 PolarHBondContact O-N 2.84Å; K313-S318 WeakPolarHBondContact CA-OG 3.38Å
314	D	82.8	Confident	83.5	Confident	62 Å²	62	49 Å²	49	33%	0.332	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79.3	-16.5	-176.7	-54.3	-48.5	0	0	0	110.7	V310 A311 L475	V310-D314 HydrophobicContact CG1-CB 3.69Å; A311-D314 PolarHBondContact O-N 2.9Å; D314-L475 HydrophobicContact CB-CD1 4.31Å
315	K	80.4	Confident	83.8	Confident	64 Å²	64	42.9 Å²	42.9	28%	0.278	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-92.9	1.5	173.2	-66.8	-171.1	-168.7	165.3	0	115	Y307 V310 A311 P312 K313 E317 I476	Y307-K315 HydrophobicContact CE1-CD 4.35Å; V310-K315 HydrophobicContact CB-CG 4.35Å; V310-K315 HydrophobicContact CG1-CG 3.8Å; A311-K315 PolarHBondContact O-N 2.79Å; P312-K315 PolarHBondContact O-N 2.61Å; K313-K315 PolarHBondContact O-N 2.93Å; K315-E317 HydrophobicContact CB-CG 4.03Å; K315-E317 PolarHBondContact O-N 3.41Å; K315-I476 HydrophobicContact CB-CD1 4.29Å; K315-I476 WeakPolarHBondContact O-CD1 3.5Å
316	E	77.9	Confident	84	Confident	88 Å²	88	42 Å²	42	41%	0.411	21%	0.213	S	C	.	.	T	Hydrogen-bonded Turn	trans	61.8	27	-173.3	-53.3	-177.8	-165.5	0	0	113.6	P312 K313 H474	P312-E316 PolarHBondContact O-N 3.23Å; K313-E316 PolarHBondContact O-N 2.84Å; E316-H474 VanDerWaalsContact CD-ND1 3.27Å; E316-H474 VanDerWaalsContact OE1-CA 3.3Å; E316-H474 WeakPolarHBondContact OE1-CA 3.37Å; E316-H474 WeakPolarHBondContact OE1-CB 3.44Å; E316-H474 IonicContact OE1-CE1 2.66Å; E316-H474 IonicContact OE1-CG 2.69Å; E316-H474 IonicContact OE1-ND1 2.66Å; E316-H474 PolarHBondContact OE1-ND1 3.28Å; E316-H474 IonicContact OE2-CE1 3.39Å; E316-H474 IonicContact OE2-ND1 3.88Å; E316-H474 PolarHBondContact OE2-ND1 2.87Å
317	E	81.4	Confident	84.2	Confident	58 Å²	58	39 Å²	39	27%	0.271	19%	0.191	S	C	.	.			trans	-105.6	27.6	178.6	-62.2	-177.7	-173	0	0	111.7	Y307 P312 K315 D319 M320 I324	Y307-E317 PolarHBondContact OH-OE2 3.43Å; P312-E317 HydrophobicContact CB-CB 4.45Å; P312-E317 PolarHBondContact O-N 3.14Å; K315-E317 HydrophobicContact CB-CG 4.03Å; K315-E317 PolarHBondContact O-N 3.41Å; E317-D319 VanDerWaalsContact C-N 3.31Å; E317-D319 PolarHBondContact O-N 2.99Å; E317-M320 HydrophobicContact CB-CE 3.67Å; E317-M320 HydrophobicContact CG-CE 3.52Å; E317-M320 PolarHBondContact O-N 3.46Å; E317-I324 HydrophobicContact CB-CD1 4.06Å
318	S	83.2	Confident	84.5	Confident	11 Å²	11	39.5 Å²	39.5	8%	0.077	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	-69.4	-29.5	-177.5	-59.8	0	0	0	0	112.9	K313 M320 I321	K313-S318 WeakPolarHBondContact CA-OG 3.38Å; S318-M320 PolarHBondContact O-N 2.99Å; S318-I321 VanDerWaalsContact O-CB 3.29Å; S318-I321 WeakPolarHBondContact O-CB 3.36Å; S318-I321 VanDerWaalsContact O-CG2 3.26Å; S318-I321 WeakPolarHBondContact O-CG2 3.41Å; S318-I321 PolarHBondContact O-N 2.97Å
319	D	76.6	Confident	85	Confident	51 Å²	51	38.6 Å²	38.6	27%	0.273	18%	0.184	S	C	.	.	G	3₁₀ helix	trans	-65.5	-24.4	173.6	62.8	-27.5	0	0	0	112.4	E317	E317-D319 VanDerWaalsContact C-N 3.31Å; E317-D319 PolarHBondContact O-N 2.99Å
320	M	82.1	Confident	85.6	Confident	33 Å²	33	29.7 Å²	29.7	16%	0.163	15%	0.15	C	C	.	.	G	3₁₀ helix	trans	-97.2	11.9	175.7	-61.7	-171.6	-65.7	0	0	113.2	A153 V157 E317 S318 L322 P323 I324	A153-M320 HydrophobicContact CB-CG 4.01Å; A153-M320 HydrophobicContact CB-SD 3.9Å; V157-M320 HydrophobicContact CG2-SD 4.25Å; E317-M320 HydrophobicContact CB-CE 3.67Å; E317-M320 HydrophobicContact CG-CE 3.52Å; E317-M320 PolarHBondContact O-N 3.46Å; S318-M320 PolarHBondContact O-N 2.99Å; M320-L322 PolarHBondContact O-N 3.2Å; M320-P323 HydrophobicContact CB-CG 4.14Å; M320-P323 WeakPolarHBondContact O-CD 3.5Å; M320-P323 WeakPolarHBondContact O-CG 3.43Å; M320-I324 HydrophobicContact CB-CD1 3.91Å; M320-I324 HydrophobicContact CB-CG1 4.28Å; M320-I324 WeakPolarHBondContact O-CB 3.3Å; M320-I324 WeakPolarHBondContact O-CD1 3.32Å; M320-I324 WeakPolarHBondContact O-CG1 3.29Å; M320-I324 PolarHBondContact O-N 3.39Å
321	I	89	Confident	86	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-57.7	-38.2	-176	-168.5	63.3	0	0	0	112.8	A74 Y78 W302 P312 S318 I324 V325	A74-I321 HydrophobicContact CB-CG2 3.99Å; Y78-I321 HydrophobicContact CD1-CB 4.01Å; Y78-I321 HydrophobicContact CD1-CD1 3.93Å; Y78-I321 HydrophobicContact CD1-CG1 3.81Å; Y78-I321 HydrophobicContact CD1-CG2 4.44Å; Y78-I321 HydrophobicContact CD2-CD1 3.83Å; Y78-I321 HydrophobicContact CD2-CG1 3.87Å; Y78-I321 HydrophobicContact CE1-CD1 3.84Å; Y78-I321 HydrophobicContact CE1-CG1 4.25Å; Y78-I321 HydrophobicContact CE2-CD1 3.76Å; Y78-I321 HydrophobicContact CE2-CG1 4.32Å; Y78-I321 HydrophobicContact CG-CB 4.19Å; Y78-I321 HydrophobicContact CG-CD1 3.92Å; Y78-I321 HydrophobicContact CG-CG1 3.59Å; Y78-I321 HydrophobicContact CG-CG2 4.42Å; W302-I321 HydrophobicContact CH2-CD1 4Å; W302-I321 HydrophobicContact CZ2-CD1 3.52Å; P312-I321 HydrophobicContact CB-CD1 4.15Å; P312-I321 HydrophobicContact CG-CD1 3.99Å; S318-I321 VanDerWaalsContact O-CB 3.29Å; S318-I321 WeakPolarHBondContact O-CB 3.36Å; S318-I321 VanDerWaalsContact O-CG2 3.26Å; S318-I321 WeakPolarHBondContact O-CG2 3.41Å; S318-I321 PolarHBondContact O-N 2.97Å; I321-I324 PolarHBondContact O-N 3.43Å; I321-V325 HydrophobicContact CD1-CG2 4.37Å; I321-V325 HydrophobicContact CG1-CG2 4.29Å; I321-V325 WeakPolarHBondContact O-CB 3.24Å; I321-V325 VanDerWaalsContact O-CG2 3.3Å; I321-V325 WeakPolarHBondContact O-CG2 3.47Å; I321-V325 PolarHBondContact O-N 3.13Å
322	L	89.8	Confident	86.1	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-63.2	-56.6	179.9	-172.1	156.8	0	0	0	111.6	I70 A74 L201 I293 M320 I324 V325 L326 V342	I70-L322 HydrophobicContact CG2-CD1 3.24Å; A74-L322 HydrophobicContact CB-CB 3.92Å; A74-L322 HydrophobicContact CB-CD1 4.01Å; A74-L322 HydrophobicContact CB-CG 4.44Å; L201-L322 HydrophobicContact CD2-CD2 4.39Å; I293-L322 HydrophobicContact CD1-CD1 4.49Å; I293-L322 HydrophobicContact CD1-CG 4.33Å; I293-L322 HydrophobicContact CG2-CB 4.2Å; I293-L322 HydrophobicContact CG2-CG 3.87Å; M320-L322 PolarHBondContact O-N 3.2Å; L322-I324 VanDerWaalsContact C-N 3.28Å; L322-I324 PolarHBondContact O-N 3.01Å; L322-V325 PolarHBondContact O-N 3.48Å; L322-L326 HydrophobicContact CD2-CD1 3.7Å; L322-L326 HydrophobicContact CD2-CG 4.29Å; L322-L326 WeakPolarHBondContact O-CG 3.5Å; L322-L326 PolarHBondContact O-N 2.99Å; L322-L326 VanDerWaalsContact O-N 3.09Å; L322-V342 HydrophobicContact CD2-CB 4.49Å; L322-V342 HydrophobicContact CD2-CG1 4.45Å; L322-V342 HydrophobicContact CD2-CG2 3.27Å
323	P	88.1	Confident	86.1	Confident	1 Å²	1	40.1 Å²	40.1	1%	0.006	20%	0.197	C	C	.	.	H	α-helix	trans	-62.1	-34.1	176.3	20.6	-30.7	0	0	0	113	V157 M320 L326 Q327 L339	V157-P323 HydrophobicContact CG1-CB 4.31Å; M320-P323 HydrophobicContact CB-CG 4.14Å; M320-P323 WeakPolarHBondContact O-CD 3.5Å; M320-P323 WeakPolarHBondContact O-CG 3.43Å; P323-L326 PolarHBondContact O-N 2.9Å; P323-Q327 WeakPolarHBondContact O-CB 3.37Å; P323-Q327 PolarHBondContact O-N 3.38Å; P323-L339 HydrophobicContact CB-CD2 3.47Å; P323-L339 VanDerWaalsContact CB-CD2 3.47Å
324	I	88.8	Confident	86.4	Confident	3 Å²	3	38.9 Å²	38.9	2%	0.015	19%	0.193	C	C	.	.	H	α-helix	trans	-62.6	-46.6	175.8	-69.8	168.2	0	0	0	111.3	W302 Y307 P312 E317 M320 I321 L322 L326 Q327 H328	W302-I324 HydrophobicContact CH2-CG2 3.62Å; W302-I324 HydrophobicContact CZ3-CG2 3.53Å; Y307-I324 HydrophobicContact CD2-CG2 3.75Å; Y307-I324 HydrophobicContact CE2-CD1 3.85Å; Y307-I324 HydrophobicContact CE2-CG1 4.14Å; Y307-I324 HydrophobicContact CE2-CG2 3.88Å; Y307-I324 HydrophobicContact CG-CG2 4.33Å; P312-I324 HydrophobicContact CB-CD1 4.07Å; P312-I324 HydrophobicContact CG-CD1 4.25Å; P312-I324 HydrophobicContact CG-CG2 4.08Å; E317-I324 HydrophobicContact CB-CD1 4.06Å; M320-I324 HydrophobicContact CB-CD1 3.91Å; M320-I324 HydrophobicContact CB-CG1 4.28Å; M320-I324 WeakPolarHBondContact O-CB 3.3Å; M320-I324 WeakPolarHBondContact O-CD1 3.32Å; M320-I324 WeakPolarHBondContact O-CG1 3.29Å; M320-I324 PolarHBondContact O-N 3.39Å; I321-I324 PolarHBondContact O-N 3.43Å; L322-I324 VanDerWaalsContact C-N 3.28Å; L322-I324 PolarHBondContact O-N 3.01Å; I324-L326 VanDerWaalsContact C-N 3.32Å; I324-L326 PolarHBondContact O-N 3.48Å; I324-Q327 PolarHBondContact O-N 3.27Å; I324-H328 WeakPolarHBondContact O-CB 3.27Å; I324-H328 PolarHBondContact O-CD2 2.97Å; I324-H328 PolarHBondContact O-N 3.49Å
325	V	92.3	Very high	86.6	Confident	0 Å²	0	36 Å²	36	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-59.1	-45.6	175.8	162.2	0	0	0	0	110.3	A208 I293 I296 W302 I321 L322 Q327 L329	A208-V325 HydrophobicContact CB-CG1 4.2Å; I293-V325 HydrophobicContact CG2-CB 3.85Å; I293-V325 HydrophobicContact CG2-CG1 3.74Å; I293-V325 HydrophobicContact CG2-CG2 4.24Å; I296-V325 HydrophobicContact CG2-CG1 4.16Å; W302-V325 HydrophobicContact CH2-CG2 3.93Å; W302-V325 HydrophobicContact CZ2-CG2 4.31Å; I321-V325 HydrophobicContact CD1-CG2 4.37Å; I321-V325 HydrophobicContact CG1-CG2 4.29Å; I321-V325 WeakPolarHBondContact O-CB 3.24Å; I321-V325 VanDerWaalsContact O-CG2 3.3Å; I321-V325 WeakPolarHBondContact O-CG2 3.47Å; I321-V325 PolarHBondContact O-N 3.13Å; L322-V325 PolarHBondContact O-N 3.48Å; V325-Q327 VanDerWaalsContact C-N 3.33Å; V325-Q327 PolarHBondContact O-N 3Å; V325-L329 HydrophobicContact CB-CD1 4.37Å; V325-L329 HydrophobicContact CG1-CD1 4.04Å; V325-L329 HydrophobicContact CG2-CD1 4.13Å; V325-L329 WeakPolarHBondContact O-CA 3.05Å; V325-L329 VanDerWaalsContact O-CB 3.27Å; V325-L329 WeakPolarHBondContact O-CB 3.4Å; V325-L329 PolarHBondContact O-N 3.46Å
326	L	91.3	Very high	86.8	Confident	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-62.8	-39	177.9	-65.1	-178.5	0	0	0	112.2	L201 S204 I293 L322 P323 I324 C330 S335 L339 V342	L201-L326 HydrophobicContact CD2-CD1 4.36Å; S204-L326 WeakPolarHBondContact OG-CD2 3.31Å; I293-L326 HydrophobicContact CD1-CD2 4.29Å; L322-L326 HydrophobicContact CD2-CD1 3.7Å; L322-L326 HydrophobicContact CD2-CG 4.29Å; L322-L326 WeakPolarHBondContact O-CG 3.5Å; L322-L326 PolarHBondContact O-N 2.99Å; L322-L326 VanDerWaalsContact O-N 3.09Å; P323-L326 PolarHBondContact O-N 2.9Å; I324-L326 VanDerWaalsContact C-N 3.32Å; I324-L326 PolarHBondContact O-N 3.48Å; L326-C330 VanDerWaalsContact O-CB 3.32Å; L326-C330 WeakPolarHBondContact O-CB 3.35Å; L326-S335 VanDerWaalsContact C-OG 3.3Å; L326-S335 WeakPolarHBondContact O-CB 3.36Å; L326-S335 PolarHBondContact O-OG 3.39Å; L326-L339 HydrophobicContact CB-CD2 4.01Å; L326-L339 HydrophobicContact CB-CG 3.97Å; L326-L339 HydrophobicContact CD1-CD2 4.06Å; L326-L339 HydrophobicContact CD1-CG 4.2Å; L326-V342 HydrophobicContact CD1-CG2 4Å
327	Q	88.5	Confident	87.1	Confident	54 Å²	54	34.6 Å²	34.6	25%	0.252	17%	0.171	S	C	.	.	H	α-helix	trans	-72.5	-43.2	-179	-171.8	173.8	29.2	0	0	113.2	V157 P323 I324 V325 S335 L339	V157-Q327 HydrophobicContact CG1-CB 4.37Å; V157-Q327 PolarHBondContact O-NE2 2.84Å; P323-Q327 WeakPolarHBondContact O-CB 3.37Å; P323-Q327 PolarHBondContact O-N 3.38Å; I324-Q327 PolarHBondContact O-N 3.27Å; V325-Q327 VanDerWaalsContact C-N 3.33Å; V325-Q327 PolarHBondContact O-N 3Å; Q327-S335 VanDerWaalsContact CA-OG 3.29Å; Q327-S335 WeakPolarHBondContact CA-OG 3.32Å; Q327-L339 HydrophobicContact CB-CD1 4.46Å
328	H	89.9	Confident	87.5	Confident	38 Å²	38	31.9 Å²	31.9	18%	0.176	16%	0.158	C	C	.	.	H	α-helix	trans	-100.6	-19.9	-167.5	-68.9	-73.6	0	0	0	114.3	T306 Y307 I324	T306-H328 PolarHBondContact OG1-ND1 3.44Å; Y307-H328 AromaticContact CD2-CD2 3.72Å; Y307-H328 AromaticContact CD2-NE2 3.57Å; Y307-H328 PolarHBondContact N-ND1 2.97Å; I324-H328 WeakPolarHBondContact O-CB 3.27Å; I324-H328 PolarHBondContact O-CD2 2.97Å; I324-H328 PolarHBondContact O-N 3.49Å
329	L	91.1	Very high	87.6	Confident	5 Å²	5	31.4 Å²	31.4	3%	0.026	15%	0.154	C	C	.	.	H	α-helix	trans	-109.3	-18.3	-176.5	-55.1	179.8	0	0	0	113.7	A208 N211 V214 I296 T300 W302 T305 V325	A208-L329 HydrophobicContact CB-CB 4.38Å; N211-L329 HydrophobicContact CB-CB 4.42Å; N211-L329 WeakPolarHBondContact ND2-CA 3.27Å; N211-L329 PolarHBondContact ND2-O 3.37Å; V214-L329 HydrophobicContact CG2-CD1 3.99Å; V214-L329 HydrophobicContact CG2-CD2 4.48Å; I296-L329 HydrophobicContact CG2-CD1 3.72Å; T300-L329 HydrophobicContact CG2-CD1 4.01Å; T300-L329 HydrophobicContact CG2-CD2 3.94Å; T300-L329 WeakPolarHBondContact OG1-CD1 3.35Å; W302-L329 HydrophobicContact CH2-CD1 4.49Å; T305-L329 HydrophobicContact CG2-CD2 3.67Å; V325-L329 HydrophobicContact CB-CD1 4.37Å; V325-L329 HydrophobicContact CG1-CD1 4.04Å; V325-L329 HydrophobicContact CG2-CD1 4.13Å; V325-L329 WeakPolarHBondContact O-CA 3.05Å; V325-L329 VanDerWaalsContact O-CB 3.27Å; V325-L329 WeakPolarHBondContact O-CB 3.4Å; V325-L329 PolarHBondContact O-N 3.46Å
330	C	91.5	Very high	88	Confident	12 Å²	12	29.3 Å²	29.3	8%	0.081	15%	0.145	C	C	.	.	S	Bend	trans	-99.1	154.1	177.2	-61.8	0	0	0	0	112.4	L326 I334	L326-C330 VanDerWaalsContact O-CB 3.32Å; L326-C330 WeakPolarHBondContact O-CB 3.35Å; C330-I334 HydrophobicContact CB-CB 4.36Å; C330-I334 HydrophobicContact CB-CG2 4.23Å
331	P	89.7	Confident	88.1	Confident	54 Å²	54	27.9 Å²	27.9	35%	0.351	14%	0.138	S	C	.	.			trans	-58.7	150.6	167.2	-22.4	32.9	0	0	0	112	F207 Y333 I334 S335	F207-P331 HydrophobicContact CD1-CG 3.82Å; F207-P331 HydrophobicContact CE1-CG 4.37Å; F207-P331 HydrophobicContact CG-CG 4.43Å; P331-Y333 PolarHBondContact O-N 2.76Å; P331-Y333 VanDerWaalsContact O-N 3.17Å; P331-I334 PolarHBondContact O-N 2.84Å; P331-S335 WeakPolarHBondContact O-CB 3.01Å; P331-S335 PolarHBondContact O-N 2.83Å
332	P	85.3	Confident	87.9	Confident	75 Å²	75	27.9 Å²	27.9	49%	0.487	14%	0.139	S	C	.	.	H	α-helix	trans	-51.2	-46	-173.1	-29.8	35.1	0	0	0	114.8	I334 S335 F336	P332-I334 PolarHBondContact O-N 2.97Å; P332-S335 WeakPolarHBondContact O-CB 3.36Å; P332-S335 PolarHBondContact O-N 2.91Å; P332-F336 HydrophobicContact CB-CE2 4.1Å; P332-F336 HydrophobicContact CB-CZ 4.45Å; P332-F336 WeakPolarHBondContact O-CD2 3.4Å; P332-F336 VanDerWaalsContact O-CG 3.24Å; P332-F336 WeakPolarHBondContact O-CG 3.34Å; P332-F336 PolarHBondContact O-N 3.42Å
333	Y	86.1	Confident	87.6	Confident	175 Å²	175	27.9 Å²	27.9	69%	0.686	14%	0.139	S	C	*	.	H	α-helix	trans	-64.3	-39.6	-179.2	-55.1	-65.9	0	0	0	113.3	P331 F337	P331-Y333 PolarHBondContact O-N 2.76Å; P331-Y333 VanDerWaalsContact O-N 3.17Å; Y333-F337 WeakPolarHBondContact O-CB 3.48Å; Y333-F337 PolarHBondContact O-N 2.87Å
334	I	89.3	Confident	87.2	Confident	32 Å²	32	27.9 Å²	27.9	16%	0.164	14%	0.138	C	C	.	.	H	α-helix	trans	-73.1	-38.1	178	-58.2	-55.4	0	0	0	110.3	I203 F207 C330 P331 P332 F337 G338	I203-I334 HydrophobicContact CG2-CD1 3.87Å; I203-I334 HydrophobicContact CG2-CG2 4.32Å; F207-I334 HydrophobicContact CB-CG2 4.5Å; F207-I334 HydrophobicContact CD2-CB 4.49Å; F207-I334 HydrophobicContact CD2-CD1 4.3Å; F207-I334 HydrophobicContact CD2-CG1 3.87Å; F207-I334 HydrophobicContact CD2-CG2 4Å; F207-I334 HydrophobicContact CE2-CD1 3.94Å; F207-I334 HydrophobicContact CE2-CG1 3.89Å; F207-I334 HydrophobicContact CG-CG1 4.26Å; F207-I334 HydrophobicContact CG-CG2 4.45Å; F207-I334 HydrophobicContact CZ-CD1 4.43Å; F207-I334 HydrophobicContact CZ-CG1 4.27Å; C330-I334 HydrophobicContact CB-CB 4.36Å; C330-I334 HydrophobicContact CB-CG2 4.23Å; P331-I334 PolarHBondContact O-N 2.84Å; P332-I334 PolarHBondContact O-N 2.97Å; I334-F337 PolarHBondContact O-N 3.1Å; I334-G338 PolarHBondContact O-N 2.9Å
335	S	86.8	Confident	86.9	Confident	3 Å²	3	27.7 Å²	27.7	2%	0.021	14%	0.138	C	C	.	.	H	α-helix	trans	-57.1	-53.2	174.3	-174.9	0	0	0	0	111.2	L326 Q327 P331 P332 F337 G338 L339	L326-S335 VanDerWaalsContact C-OG 3.3Å; L326-S335 WeakPolarHBondContact O-CB 3.36Å; L326-S335 PolarHBondContact O-OG 3.39Å; Q327-S335 VanDerWaalsContact CA-OG 3.29Å; Q327-S335 WeakPolarHBondContact CA-OG 3.32Å; P331-S335 WeakPolarHBondContact O-CB 3.01Å; P331-S335 PolarHBondContact O-N 2.83Å; P332-S335 WeakPolarHBondContact O-CB 3.36Å; P332-S335 PolarHBondContact O-N 2.91Å; S335-F337 VanDerWaalsContact C-N 3.34Å; S335-F337 PolarHBondContact O-N 3.49Å; S335-G338 PolarHBondContact O-N 2.74Å; S335-L339 VanDerWaalsContact O-CB 3.26Å; S335-L339 WeakPolarHBondContact O-CB 3.22Å; S335-L339 VanDerWaalsContact O-CG 3.22Å; S335-L339 WeakPolarHBondContact O-CG 3.42Å; S335-L339 PolarHBondContact O-N 2.98Å; S335-L339 WeakPolarHBondContact OG-CD1 3.1Å
336	F	83.9	Confident	86.4	Confident	31 Å²	31	27.7 Å²	27.7	14%	0.136	14%	0.138	C	C	.	.	H	α-helix	trans	-63.4	-39.6	-179.5	-59.8	-36.9	0	0	0	112.5	H4 E6 A10 P332 G340	H4-F336 HydrophobicContact CB-CE1 4.36Å; H4-F336 HydrophobicContact CB-CZ 4.35Å; E6-F336 HydrophobicContact CB-CD2 4.35Å; E6-F336 HydrophobicContact CB-CE2 3.72Å; E6-F336 HydrophobicContact CB-CZ 4.34Å; A10-F336 HydrophobicContact CB-CB 4.37Å; P332-F336 HydrophobicContact CB-CE2 4.1Å; P332-F336 HydrophobicContact CB-CZ 4.45Å; P332-F336 WeakPolarHBondContact O-CD2 3.4Å; P332-F336 VanDerWaalsContact O-CG 3.24Å; P332-F336 WeakPolarHBondContact O-CG 3.34Å; P332-F336 PolarHBondContact O-N 3.42Å; F336-G340 PolarHBondContact O-N 3.37Å
337	F	85.5	Confident	85.9	Confident	91 Å²	91	27.8 Å²	27.8	40%	0.399	14%	0.138	S	C	.	.	H	α-helix	trans	-65.6	-46.2	176.3	-173.2	-111.6	0	0	0	111.8	L199 G200 I203 Y333 I334 S335 G340 A341	L199-F337 HydrophobicContact CB-CE1 4.07Å; L199-F337 HydrophobicContact CB-CZ 4.26Å; G200-F337 VanDerWaalsContact CA-CE1 3.44Å; I203-F337 HydrophobicContact CD1-CE1 4.41Å; Y333-F337 WeakPolarHBondContact O-CB 3.48Å; Y333-F337 PolarHBondContact O-N 2.87Å; I334-F337 PolarHBondContact O-N 3.1Å; S335-F337 VanDerWaalsContact C-N 3.34Å; S335-F337 PolarHBondContact O-N 3.49Å; F337-G340 PolarHBondContact O-N 3.34Å; F337-A341 WeakPolarHBondContact O-CB 3.09Å; F337-A341 PolarHBondContact O-N 2.84Å
338	G	87.9	Confident	85.6	Confident	0 Å²	0	25.2 Å²	25.2	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-63.3	-43.4	176.8	0	0	0	0	0	112.8	I334 S335 A341 V342	I334-G338 PolarHBondContact O-N 2.9Å; S335-G338 PolarHBondContact O-N 2.74Å; G338-A341 WeakPolarHBondContact O-CA 3.18Å; G338-A341 VanDerWaalsContact O-CB 3.28Å; G338-A341 WeakPolarHBondContact O-CB 3.3Å; G338-A341 PolarHBondContact O-N 3.12Å; G338-A341 VanDerWaalsContact O-N 3.15Å; G338-V342 WeakPolarHBondContact O-CG2 3.44Å; G338-V342 PolarHBondContact O-N 2.84Å
339	L	85.9	Confident	85.5	Confident	1 Å²	1	23.4 Å²	23.4	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-68	-36.4	178	-72.9	169.8	0	0	0	112.6	T154 I158 P323 L326 Q327 S335 A341 V342 S343	T154-L339 HydrophobicContact CG2-CD2 4.39Å; I158-L339 HydrophobicContact CD1-CB 3.65Å; I158-L339 HydrophobicContact CD1-CG 4.49Å; I158-L339 HydrophobicContact CG1-CB 3.79Å; I158-L339 HydrophobicContact CG1-CD1 3.71Å; I158-L339 HydrophobicContact CG1-CD2 4.37Å; I158-L339 HydrophobicContact CG1-CG 4.16Å; P323-L339 HydrophobicContact CB-CD2 3.47Å; P323-L339 VanDerWaalsContact CB-CD2 3.47Å; L326-L339 HydrophobicContact CB-CD2 4.01Å; L326-L339 HydrophobicContact CB-CG 3.97Å; L326-L339 HydrophobicContact CD1-CD2 4.06Å; L326-L339 HydrophobicContact CD1-CG 4.2Å; Q327-L339 HydrophobicContact CB-CD1 4.46Å; S335-L339 VanDerWaalsContact O-CB 3.26Å; S335-L339 WeakPolarHBondContact O-CB 3.22Å; S335-L339 VanDerWaalsContact O-CG 3.22Å; S335-L339 WeakPolarHBondContact O-CG 3.42Å; S335-L339 PolarHBondContact O-N 2.98Å; S335-L339 WeakPolarHBondContact OG-CD1 3.1Å; L339-A341 VanDerWaalsContact C-N 3.3Å; L339-V342 PolarHBondContact O-N 2.88Å; L339-S343 PolarHBondContact O-N 3.08Å; L339-S343 PolarHBondContact O-OG 3.03Å
340	G	85.3	Confident	85.2	Confident	8 Å²	8	23.2 Å²	23.2	8%	0.082	12%	0.116	C	C	.	.	H	α-helix	trans	-62.8	-38.6	169.1	0	0	0	0	0	111.9	F336 F337 S343 A344	F336-G340 PolarHBondContact O-N 3.37Å; F337-G340 PolarHBondContact O-N 3.34Å; G340-S343 WeakPolarHBondContact O-CB 3.25Å; G340-S343 PolarHBondContact O-N 3.33Å; G340-A344 PolarHBondContact O-N 3.28Å
341	A	84.7	Confident	85	Confident	2 Å²	2	22.6 Å²	22.6	2%	0.017	11%	0.113	C	C	.	.	H	α-helix	trans	-67	-38.9	176.2	0	0	0	0	0	112.8	C196 I197 F337 G338 L339 S343 A344 A345	C196-A341 VanDerWaalsContact O-CB 3.3Å; C196-A341 WeakPolarHBondContact O-CB 3.34Å; I197-A341 VanDerWaalsContact CG1-O 3.3Å; I197-A341 WeakPolarHBondContact CG1-O 3.16Å; F337-A341 WeakPolarHBondContact O-CB 3.09Å; F337-A341 PolarHBondContact O-N 2.84Å; G338-A341 WeakPolarHBondContact O-CA 3.18Å; G338-A341 VanDerWaalsContact O-CB 3.28Å; G338-A341 WeakPolarHBondContact O-CB 3.3Å; G338-A341 PolarHBondContact O-N 3.12Å; G338-A341 VanDerWaalsContact O-N 3.15Å; L339-A341 VanDerWaalsContact C-N 3.3Å; A341-S343 VanDerWaalsContact C-N 3.35Å; A341-A344 WeakPolarHBondContact O-CB 3.15Å; A341-A344 PolarHBondContact O-N 3.46Å; A341-A345 PolarHBondContact O-N 3.09Å; A341-A345 VanDerWaalsContact O-N 3.13Å
342	V	83.8	Confident	84.9	Confident	1 Å²	1	20 Å²	20	1%	0.006	10%	0.096	C	C	.	.	H	α-helix	trans	-61	-47	171	176.8	0	0	0	0	110.1	T154 L201 L322 L326 G338 L339 A344 A345 V346	T154-V342 HydrophobicContact CG2-CB 4.08Å; T154-V342 HydrophobicContact CG2-CG1 3.91Å; L201-V342 HydrophobicContact CD2-CG2 3.98Å; L322-V342 HydrophobicContact CD2-CB 4.49Å; L322-V342 HydrophobicContact CD2-CG1 4.45Å; L322-V342 HydrophobicContact CD2-CG2 3.27Å; L326-V342 HydrophobicContact CD1-CG2 4Å; G338-V342 WeakPolarHBondContact O-CG2 3.44Å; G338-V342 PolarHBondContact O-N 2.84Å; L339-V342 PolarHBondContact O-N 2.88Å; V342-A344 PolarHBondContact O-N 3.31Å; V342-A345 WeakPolarHBondContact O-CB 3.26Å; V342-A345 PolarHBondContact O-N 3.21Å; V342-A345 VanDerWaalsContact O-N 3.11Å; V342-V346 HydrophobicContact CG1-CG2 4.22Å; V342-V346 WeakPolarHBondContact O-CG2 3.15Å; V342-V346 PolarHBondContact O-N 3.5Å; V342-V346 VanDerWaalsContact O-N 3.1Å
343	S	83.8	Confident	85.2	Confident	0 Å²	0	16.5 Å²	16.5	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-56.8	-38.4	176	-58	0	0	0	0	112.1	T154 L339 G340 A341 V346 M347	T154-S343 WeakPolarHBondContact CG2-OG 3.3Å; L339-S343 PolarHBondContact O-N 3.08Å; L339-S343 PolarHBondContact O-OG 3.03Å; G340-S343 WeakPolarHBondContact O-CB 3.25Å; G340-S343 PolarHBondContact O-N 3.33Å; A341-S343 VanDerWaalsContact C-N 3.35Å; S343-V346 PolarHBondContact O-N 3.11Å; S343-M347 VanDerWaalsContact O-CB 3.27Å; S343-M347 WeakPolarHBondContact O-CB 3.41Å; S343-M347 PolarHBondContact O-N 3.01Å
344	A	80.9	Confident	85.4	Confident	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-57.8	-49.6	174.1	0	0	0	0	0	112.9	F14 Q193 I197 G340 A341 V342 V346 M347 S348	F14-A344 HydrophobicContact CE1-CB 3.54Å; F14-A344 HydrophobicContact CE2-CB 4.19Å; F14-A344 HydrophobicContact CZ-CB 3.19Å; Q193-A344 HydrophobicContact CB-CB 4.05Å; Q193-A344 HydrophobicContact CG-CB 4.05Å; Q193-A344 PolarHBondContact NE2-O 3.09Å; I197-A344 HydrophobicContact CG1-CB 4.21Å; G340-A344 PolarHBondContact O-N 3.28Å; A341-A344 WeakPolarHBondContact O-CB 3.15Å; A341-A344 PolarHBondContact O-N 3.46Å; V342-A344 PolarHBondContact O-N 3.31Å; A344-V346 VanDerWaalsContact C-N 3.31Å; A344-V346 PolarHBondContact O-N 3.12Å; A344-M347 PolarHBondContact O-N 3.46Å; A344-S348 PolarHBondContact O-N 3.18Å; A344-S348 VanDerWaalsContact O-N 3.09Å; A344-S348 PolarHBondContact O-OG 3.4Å
345	A	81.9	Confident	85.4	Confident	0 Å²	0	6.8 Å²	6.8	0%	0	3%	0.033	C	C	.	.	H	α-helix	trans	-59.8	-42.9	179.3	0	0	0	0	0	112.2	I70 I197 A341 V342 M347 S348 S349	I70-A345 HydrophobicContact CD1-CB 3.73Å; I197-A345 HydrophobicContact CD1-CB 3.33Å; I197-A345 HydrophobicContact CG1-CB 3.76Å; A341-A345 PolarHBondContact O-N 3.09Å; A341-A345 VanDerWaalsContact O-N 3.13Å; V342-A345 WeakPolarHBondContact O-CB 3.26Å; V342-A345 PolarHBondContact O-N 3.21Å; V342-A345 VanDerWaalsContact O-N 3.11Å; A345-M347 VanDerWaalsContact C-N 3.32Å; A345-S348 PolarHBondContact O-OG 3.3Å; A345-S349 PolarHBondContact O-N 2.93Å; A345-S349 PolarHBondContact O-OG 2.98Å
346	V	81	Confident	85.6	Confident	0 Å²	0	6.7 Å²	6.7	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-71.1	-37.9	-176.6	-162.1	0	0	0	0	109.6	I147 A150 L151 V342 S343 A344 S349 A350	I147-V346 HydrophobicContact CB-CG1 4.2Å; I147-V346 HydrophobicContact CG2-CB 4.4Å; I147-V346 HydrophobicContact CG2-CG1 3.33Å; I147-V346 WeakPolarHBondContact CG2-O 3.19Å; I147-V346 WeakPolarHBondContact O-CG1 3.1Å; A150-V346 HydrophobicContact CB-CG1 4.29Å; L151-V346 HydrophobicContact CB-CB 3.99Å; L151-V346 HydrophobicContact CB-CG1 3.56Å; L151-V346 HydrophobicContact CD1-CB 4.11Å; L151-V346 HydrophobicContact CG-CB 4.44Å; L151-V346 HydrophobicContact CG-CG1 4.46Å; V342-V346 HydrophobicContact CG1-CG2 4.22Å; V342-V346 WeakPolarHBondContact O-CG2 3.15Å; V342-V346 PolarHBondContact O-N 3.5Å; V342-V346 VanDerWaalsContact O-N 3.1Å; S343-V346 PolarHBondContact O-N 3.11Å; A344-V346 VanDerWaalsContact C-N 3.31Å; A344-V346 PolarHBondContact O-N 3.12Å; V346-S349 PolarHBondContact O-N 3.03Å; V346-A350 PolarHBondContact O-N 3Å
347	M	81.4	Confident	86.1	Confident	2 Å²	2	5.3 Å²	5.3	1%	0.01	3%	0.027	C	C	.	.	H	α-helix	trans	-65.5	-40.9	178.9	-171.9	170.1	169.7	0	0	112.9	Y15 I18 I173 Y177 S343 A344 A345 S349 A350 D351	Y15-M347 HydrophobicContact CD1-SD 4.01Å; Y15-M347 HydrophobicContact CE1-SD 3.92Å; I18-M347 HydrophobicContact CB-CE 4.3Å; I18-M347 HydrophobicContact CG2-CE 3.69Å; I18-M347 HydrophobicContact CG2-SD 4.42Å; I173-M347 HydrophobicContact CG2-CE 3.87Å; Y177-M347 HydrophobicContact CD1-CE 3.34Å; Y177-M347 HydrophobicContact CE1-CE 3.05Å; Y177-M347 HydrophobicContact CE1-CG 3.61Å; Y177-M347 HydrophobicContact CE1-SD 4.12Å; Y177-M347 HydrophobicContact CG-CE 4.29Å; Y177-M347 VanDerWaalsContact OH-CG 3.28Å; Y177-M347 WeakPolarHBondContact OH-CG 3.2Å; Y177-M347 PolarHBondContact OH-O 3.46Å; S343-M347 VanDerWaalsContact O-CB 3.27Å; S343-M347 WeakPolarHBondContact O-CB 3.41Å; S343-M347 PolarHBondContact O-N 3.01Å; A344-M347 PolarHBondContact O-N 3.46Å; A345-M347 VanDerWaalsContact C-N 3.32Å; M347-S349 VanDerWaalsContact C-N 3.31Å; M347-S349 PolarHBondContact O-N 2.6Å; M347-A350 PolarHBondContact O-N 2.89Å; M347-D351 PolarHBondContact O-N 3.33Å; M347-D351 VanDerWaalsContact O-OD1 3.13Å
348	S	82.5	Confident	86.4	Confident	0 Å²	0	1 Å²	1	0%	0	1%	0.007	C	C	.	.	H	α-helix	trans	-70.2	-18.5	178.2	59	0	0	0	0	115.1	D190 Q193 A344 A345 D351 S352	D190-S348 VanDerWaalsContact OD1-CB 3.26Å; D190-S348 WeakPolarHBondContact OD1-CB 3.31Å; Q193-S348 VanDerWaalsContact OE1-CB 3.28Å; A344-S348 PolarHBondContact O-N 3.18Å; A344-S348 VanDerWaalsContact O-N 3.09Å; A344-S348 PolarHBondContact O-OG 3.4Å; A345-S348 PolarHBondContact O-OG 3.3Å; S348-D351 WeakPolarHBondContact CA-OD1 3.43Å; S348-S352 WeakPolarHBondContact O-CB 3.28Å; S348-S352 PolarHBondContact O-OG 3.25Å
349	S	87.1	Confident	86.5	Confident	0 Å²	0	1 Å²	1	0%	0	1%	0.007	C	C	.	.	H	α-helix	trans	-89.5	-32.8	172.6	-58.1	0	0	0	0	111.4	T63 G66 I147 A345 V346 M347 S353	T63-S349 PolarHBondContact O-OG 2.98Å; G66-S349 WeakPolarHBondContact CA-OG 3.4Å; I147-S349 VanDerWaalsContact CD1-CB 3.45Å; A345-S349 PolarHBondContact O-N 2.93Å; A345-S349 PolarHBondContact O-OG 2.98Å; V346-S349 PolarHBondContact O-N 3.03Å; M347-S349 VanDerWaalsContact C-N 3.31Å; M347-S349 PolarHBondContact O-N 2.6Å; S349-S353 WeakPolarHBondContact O-CB 3.35Å; S349-S353 PolarHBondContact O-N 3.36Å
350	A	86.1	Confident	86.9	Confident	0 Å²	0	1 Å²	1	0%	0	1%	0.008	C	C	.	.	H	α-helix	trans	-64.8	-48.9	-179.6	0	0	0	0	0	112	I147 L148 A174 V346 M347 S352 S353 I354	I147-A350 HydrophobicContact CG2-CB 3.71Å; L148-A350 HydrophobicContact CD2-CB 4.34Å; A174-A350 HydrophobicContact CB-CB 4.31Å; V346-A350 PolarHBondContact O-N 3Å; M347-A350 PolarHBondContact O-N 2.89Å; A350-S352 VanDerWaalsContact C-N 3.34Å; A350-S352 PolarHBondContact O-N 3.44Å; A350-S353 PolarHBondContact O-N 3.49Å; A350-I354 WeakPolarHBondContact O-CB 3.33Å; A350-I354 WeakPolarHBondContact O-CD1 3.4Å; A350-I354 WeakPolarHBondContact O-CG1 3.41Å; A350-I354 PolarHBondContact O-N 3.5Å
351	D	85.9	Confident	87.3	Confident	0 Å²	0	3.2 Å²	3.2	0%	0	2%	0.015	C	C	.	.	H	α-helix	trans	-61.6	-43	177.5	59.1	-15.8	0	0	0	112	Y177 T178 V186 M347 S348 I354 L355	Y177-D351 HydrophobicContact CE2-CB 3.71Å; Y177-D351 WeakPolarHBondContact CE2-OD2 3.42Å; Y177-D351 WeakPolarHBondContact OH-CB 3.44Å; Y177-D351 PolarHBondContact OH-OD2 3.16Å; Y177-D351 VanDerWaalsContact OH-OD2 3.09Å; T178-D351 HydrophobicContact CG2-CB 4.18Å; T178-D351 WeakPolarHBondContact OG1-CA 3.04Å; T178-D351 WeakPolarHBondContact OG1-CB 3.43Å; V186-D351 WeakPolarHBondContact CG1-OD2 3.39Å; V186-D351 HydrophobicContact CG2-CB 4.19Å; V186-D351 WeakPolarHBondContact CG2-OD2 3.49Å; M347-D351 PolarHBondContact O-N 3.33Å; M347-D351 VanDerWaalsContact O-OD1 3.13Å; S348-D351 WeakPolarHBondContact CA-OD1 3.43Å; D351-I354 PolarHBondContact O-N 3.3Å; D351-L355 WeakPolarHBondContact O-CB 3.27Å; D351-L355 PolarHBondContact O-N 3.43Å
352	S	88.4	Confident	87.7	Confident	0 Å²	0	3.1 Å²	3.1	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-61.8	-44.8	179.3	-65.3	0	0	0	0	112.3	R262 S348 A350 S356	R262-S352 PolarHBondContact NH2-OG 3.47Å; S348-S352 WeakPolarHBondContact O-CB 3.28Å; S348-S352 PolarHBondContact O-OG 3.25Å; A350-S352 VanDerWaalsContact C-N 3.34Å; A350-S352 PolarHBondContact O-N 3.44Å; S352-S356 WeakPolarHBondContact O-CB 3.36Å; S352-S356 PolarHBondContact O-N 2.93Å
353	S	90.7	Very high	87.9	Confident	0 Å²	0	5.7 Å²	5.7	0%	0	2%	0.024	C	C	.	.	H	α-helix	trans	-69.3	-45.6	177.7	-176	0	0	0	0	112.5	E140 W143 S144 S349 A350 S356 A357	E140-S353 PolarHBondContact O-OG 2.83Å; E140-S353 VanDerWaalsContact O-OG 3.05Å; E140-S353 VanDerWaalsContact OE2-CA 3.31Å; E140-S353 WeakPolarHBondContact OE2-CA 3.32Å; E140-S353 WeakPolarHBondContact OE2-CB 3.49Å; E140-S353 PolarHBondContact OE2-OG 3.35Å; W143-S353 VanDerWaalsContact CE3-CB 3.43Å; S144-S353 WeakPolarHBondContact OG-CB 3.38Å; S144-S353 PolarHBondContact OG-OG 3.41Å; S349-S353 WeakPolarHBondContact O-CB 3.35Å; S349-S353 PolarHBondContact O-N 3.36Å; A350-S353 PolarHBondContact O-N 3.49Å; S353-S356 WeakPolarHBondContact O-CB 3.47Å; S353-S356 PolarHBondContact O-N 2.86Å; S353-A357 PolarHBondContact O-N 3.47Å
354	I	91.1	Very high	88.2	Confident	2 Å²	2	5.7 Å²	5.7	1%	0.01	2%	0.024	C	C	.	.	H	α-helix	trans	-65.1	-44.6	178.8	-65.5	167	0	0	0	110.4	I175 A350 D351 S356 A357 S358 I387	I175-I354 HydrophobicContact CG1-CD1 4.37Å; A350-I354 WeakPolarHBondContact O-CB 3.33Å; A350-I354 WeakPolarHBondContact O-CD1 3.4Å; A350-I354 WeakPolarHBondContact O-CG1 3.41Å; A350-I354 PolarHBondContact O-N 3.5Å; D351-I354 PolarHBondContact O-N 3.3Å; I354-S356 VanDerWaalsContact C-N 3.3Å; I354-S356 PolarHBondContact O-N 3.49Å; I354-A357 PolarHBondContact O-N 3.1Å; I354-S358 WeakPolarHBondContact O-CB 3.43Å; I354-S358 PolarHBondContact O-N 2.86Å; I354-S358 PolarHBondContact O-OG 3.29Å; I354-I387 HydrophobicContact CG2-CB 4.05Å; I354-I387 HydrophobicContact CG2-CG1 4.17Å; I354-I387 HydrophobicContact CG2-CG2 3.76Å; I354-I387 WeakPolarHBondContact CG2-O 3.43Å
355	L	89.4	Confident	88.8	Confident	2 Å²	2	6.3 Å²	6.3	1%	0.01	3%	0.027	C	C	.	.	H	α-helix	trans	-62.3	-39.5	176.4	-179.8	63.5	0	0	0	111.6	T178 L183 V186 D351 S358 S359 I387	T178-L355 HydrophobicContact CG2-CB 4.27Å; L183-L355 HydrophobicContact CB-CD2 4.19Å; L183-L355 HydrophobicContact CD1-CD2 4.23Å; V186-L355 HydrophobicContact CG2-CD2 4.04Å; D351-L355 WeakPolarHBondContact O-CB 3.27Å; D351-L355 PolarHBondContact O-N 3.43Å; L355-S358 PolarHBondContact O-N 2.84Å; L355-S359 VanDerWaalsContact O-CB 3.29Å; L355-S359 WeakPolarHBondContact O-CB 3.27Å; L355-S359 PolarHBondContact O-N 2.85Å; L355-S359 PolarHBondContact O-OG 3.29Å; L355-I387 HydrophobicContact CD1-CD1 4.34Å
356	S	90.8	Very high	89.2	Confident	0 Å²	0	9 Å²	9	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-59.3	-53.1	175.6	164.7	0	0	0	0	111.9	E140 Q257 V258 S352 S353 I354 S358 S359 M360	E140-S356 VanDerWaalsContact CD-OG 3.29Å; E140-S356 PolarHBondContact OE1-OG 3.17Å; Q257-S356 WeakPolarHBondContact CB-OG 3.11Å; Q257-S356 WeakPolarHBondContact CG-OG 3.29Å; V258-S356 PolarHBondContact N-OG 3.12Å; S352-S356 WeakPolarHBondContact O-CB 3.36Å; S352-S356 PolarHBondContact O-N 2.93Å; S353-S356 WeakPolarHBondContact O-CB 3.47Å; S353-S356 PolarHBondContact O-N 2.86Å; I354-S356 VanDerWaalsContact C-N 3.3Å; I354-S356 PolarHBondContact O-N 3.49Å; S356-S358 VanDerWaalsContact C-N 3.33Å; S356-S358 PolarHBondContact O-N 2.91Å; S356-S359 PolarHBondContact O-N 2.99Å; S356-M360 PolarHBondContact O-N 3.37Å
357	A	93.5	Very high	89.4	Confident	2 Å²	2	10.3 Å²	10.3	2%	0.017	4%	0.044	C	C	.	.	H	α-helix	trans	-57.3	-45.6	177.5	0	0	0	0	0	112	L137 E140 S353 I354 M360 F361 F390	L137-A357 HydrophobicContact CD1-CB 3.83Å; E140-A357 HydrophobicContact CB-CB 3.88Å; E140-A357 HydrophobicContact CG-CB 4.21Å; S353-A357 PolarHBondContact O-N 3.47Å; I354-A357 PolarHBondContact O-N 3.1Å; A357-M360 PolarHBondContact O-N 3.2Å; A357-F361 PolarHBondContact O-N 3.24Å; A357-F390 HydrophobicContact CB-CD2 3.68Å; A357-F390 HydrophobicContact CB-CE2 4.13Å; A357-F390 HydrophobicContact CB-CG 4.37Å
358	S	92.3	Very high	89.4	Confident	0 Å²	0	12.1 Å²	12.1	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-65.3	-37.6	177.8	-71.3	0	0	0	0	113.4	I354 L355 S356 F361 A362 T386 I387	I354-S358 WeakPolarHBondContact O-CB 3.43Å; I354-S358 PolarHBondContact O-N 2.86Å; I354-S358 PolarHBondContact O-OG 3.29Å; L355-S358 PolarHBondContact O-N 2.84Å; S356-S358 VanDerWaalsContact C-N 3.33Å; S356-S358 PolarHBondContact O-N 2.91Å; S358-F361 PolarHBondContact O-N 3.17Å; S358-A362 VanDerWaalsContact O-CB 3.29Å; S358-A362 WeakPolarHBondContact O-CB 3.48Å; S358-A362 PolarHBondContact O-N 3.09Å; S358-T386 WeakPolarHBondContact CB-OG1 3.28Å; S358-T386 PolarHBondContact OG-OG1 3.28Å; S358-T386 VanDerWaalsContact OG-OG1 3.1Å; S358-I387 VanDerWaalsContact OG-CA 3.28Å; S358-I387 WeakPolarHBondContact OG-CA 3.39Å; S358-I387 VanDerWaalsContact OG-CG1 3.31Å; S358-I387 WeakPolarHBondContact OG-CG1 3.22Å; S358-I387 PolarHBondContact OG-N 2.91Å
359	S	90.8	Very high	89.3	Confident	0 Å²	0	14 Å²	14	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-67	-44.9	177.8	-60	0	0	0	0	111	Q261 L355 S356 A362 R363	Q261-S359 PolarHBondContact NE2-OG 3.46Å; L355-S359 VanDerWaalsContact O-CB 3.29Å; L355-S359 WeakPolarHBondContact O-CB 3.27Å; L355-S359 PolarHBondContact O-N 2.85Å; L355-S359 PolarHBondContact O-OG 3.29Å; S356-S359 PolarHBondContact O-N 2.99Å; S359-A362 PolarHBondContact O-N 3.18Å; S359-R363 VanDerWaalsContact O-CB 3.3Å; S359-R363 WeakPolarHBondContact O-CB 3.28Å; S359-R363 PolarHBondContact O-N 2.91Å
360	M	93.3	Very high	89.1	Confident	2 Å²	2	21.5 Å²	21.5	1%	0.01	10%	0.101	C	C	.	.	H	α-helix	trans	-60	-46.3	174	-75.5	-173.7	-68.2	0	0	111.6	L117 F133 A136 E140 Q257 S356 A357 N364	L117-M360 HydrophobicContact CD1-CB 4.22Å; L117-M360 HydrophobicContact CD1-CG 4.19Å; L117-M360 HydrophobicContact CD1-SD 3.9Å; L117-M360 HydrophobicContact CG-CG 4.42Å; L117-M360 HydrophobicContact CG-SD 4.02Å; F133-M360 HydrophobicContact CD2-CB 3.87Å; F133-M360 HydrophobicContact CE2-CB 3.64Å; A136-M360 HydrophobicContact CB-CE 4.34Å; A136-M360 HydrophobicContact CB-SD 4.15Å; E140-M360 HydrophobicContact CG-CE 3.84Å; Q257-M360 HydrophobicContact CB-CE 3.72Å; Q257-M360 HydrophobicContact CB-CG 4.03Å; Q257-M360 HydrophobicContact CB-SD 3.52Å; Q257-M360 VanDerWaalsContact CB-SD 3.52Å; Q257-M360 HydrophobicContact CG-CE 4.08Å; Q257-M360 HydrophobicContact CG-CG 3.67Å; Q257-M360 HydrophobicContact CG-SD 3.89Å; S356-M360 PolarHBondContact O-N 3.37Å; A357-M360 PolarHBondContact O-N 3.2Å; M360-N364 WeakPolarHBondContact CA-OD1 3.12Å; M360-N364 WeakPolarHBondContact O-CA 3.3Å; M360-N364 WeakPolarHBondContact O-CB 3.49Å; M360-N364 PolarHBondContact O-N 3.29Å; M360-N364 PolarHBondContact O-OD1 2.94Å; M360-N364 VanDerWaalsContact O-OD1 3.08Å
361	F	94.6	Very high	89.1	Confident	54 Å²	54	27.6 Å²	27.6	24%	0.237	12%	0.124	C	C	.	.	I	π-helix	trans	-62.9	-50.1	179.4	-174.7	-88.4	0	0	0	111.7	F133 A357 S358 R363 I365 Y366 V382 T386 F390	F133-F361 AromaticContact CE1-CD2 3.75Å; F133-F361 HydrophobicContact CE1-CD2 3.75Å; F133-F361 HydrophobicContact CE2-CB 4.19Å; F133-F361 HydrophobicContact CZ-CB 3.77Å; F133-F361 AromaticContact CZ-CD2 3.73Å; F133-F361 HydrophobicContact CZ-CD2 3.73Å; F133-F361 HydrophobicContact CZ-CG 4.26Å; A357-F361 PolarHBondContact O-N 3.24Å; S358-F361 PolarHBondContact O-N 3.17Å; F361-R363 PolarHBondContact O-N 3.05Å; F361-I365 HydrophobicContact CD2-CB 4Å; F361-I365 HydrophobicContact CD2-CG1 4.16Å; F361-I365 HydrophobicContact CD2-CG2 4.13Å; F361-I365 HydrophobicContact CE2-CB 4.19Å; F361-I365 HydrophobicContact CE2-CG2 3.81Å; F361-I365 HydrophobicContact CG-CB 4.36Å; F361-I365 HydrophobicContact CZ-CG2 4.26Å; F361-I365 WeakPolarHBondContact O-CA 3.4Å; F361-I365 VanDerWaalsContact O-CB 3.3Å; F361-I365 WeakPolarHBondContact O-CB 3.27Å; F361-I365 PolarHBondContact O-N 3.38Å; F361-I365 VanDerWaalsContact O-N 3.09Å; F361-Y366 PolarHBondContact O-N 2.63Å; F361-V382 HydrophobicContact CD1-CG1 4.03Å; F361-V382 HydrophobicContact CE1-CG1 4.05Å; F361-T386 HydrophobicContact CD1-CG2 3.51Å; F361-T386 HydrophobicContact CE1-CG2 3.85Å; F361-T386 HydrophobicContact CG-CG2 4.12Å; F361-F390 HydrophobicContact CB-CE2 3.91Å; F361-F390 HydrophobicContact CB-CZ 4.03Å; F361-F390 HydrophobicContact CD2-CZ 4.06Å; F361-F390 HydrophobicContact CG-CE2 4.41Å; F361-F390 HydrophobicContact CG-CZ 4.12Å
362	A	92	Very high	89	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	15%	0.15	C	C	.	.	I	π-helix	trans	-65.4	-39.1	-175.3	0	0	0	0	0	112.3	M45 S358 S359 Y366 Q367 I379 V382 M383	M45-A362 HydrophobicContact CE-CB 3.93Å; S358-A362 VanDerWaalsContact O-CB 3.29Å; S358-A362 WeakPolarHBondContact O-CB 3.48Å; S358-A362 PolarHBondContact O-N 3.09Å; S359-A362 PolarHBondContact O-N 3.18Å; A362-Y366 WeakPolarHBondContact O-CB 3.27Å; A362-Q367 WeakPolarHBondContact O-CB 3.42Å; A362-Q367 PolarHBondContact O-N 3.44Å; A362-I379 HydrophobicContact CB-CG2 4.08Å; A362-V382 HydrophobicContact CB-CG1 4.14Å; A362-M383 HydrophobicContact CB-CB 4.41Å; A362-M383 HydrophobicContact CB-CG 3.29Å; A362-M383 HydrophobicContact CB-SD 4.42Å
363	R	88.3	Confident	88.7	Confident	55 Å²	55	41.6 Å²	41.6	21%	0.208	19%	0.191	C	C	.	.	I	π-helix	trans	-80.2	-58.2	179.2	-176.7	59.2	169.2	-165.4	-5.8	112.2	M45 T115 S359 F361 Q367 Q368	M45-R363 HydrophobicContact CE-CB 4.05Å; M45-R363 HydrophobicContact SD-CB 4.08Å; T115-R363 HydrophobicContact CG2-CB 3.86Å; T115-R363 HydrophobicContact CG2-CG 3.89Å; S359-R363 VanDerWaalsContact O-CB 3.3Å; S359-R363 WeakPolarHBondContact O-CB 3.28Å; S359-R363 PolarHBondContact O-N 2.91Å; F361-R363 PolarHBondContact O-N 3.05Å; R363-Q367 WeakPolarHBondContact O-CB 3.48Å; R363-Q368 WeakPolarHBondContact O-CG 3.45Å; R363-Q368 PolarHBondContact O-N 3.15Å
364	N	91.3	Very high	88.3	Confident	0 Å²	0	42.1 Å²	42.1	0%	0	20%	0.196	C	C	.	.	I	π-helix	trans	-81.3	-37.3	-167.8	-57	103.6	0	0	0	112.4	T115 L117 D118 Q121 M360	T115-N364 WeakPolarHBondContact CB-OD1 3.36Å; T115-N364 WeakPolarHBondContact CG2-OD1 3.04Å; T115-N364 VanDerWaalsContact OG1-CG 3.3Å; T115-N364 PolarHBondContact OG1-ND2 3.06Å; T115-N364 PolarHBondContact OG1-OD1 2.76Å; L117-N364 HydrophobicContact CB-CB 4.29Å; L117-N364 HydrophobicContact CD1-CB 4.24Å; D118-N364 PolarHBondContact OD1-ND2 2.93Å; Q121-N364 PolarHBondContact NE2-O 3.12Å; Q121-N364 VanDerWaalsContact OE1-CA 3.27Å; Q121-N364 PolarHBondContact OE1-ND2 3.07Å; M360-N364 WeakPolarHBondContact CA-OD1 3.12Å; M360-N364 WeakPolarHBondContact O-CA 3.3Å; M360-N364 WeakPolarHBondContact O-CB 3.49Å; M360-N364 PolarHBondContact O-N 3.29Å; M360-N364 PolarHBondContact O-OD1 2.94Å; M360-N364 VanDerWaalsContact O-OD1 3.08Å
365	I	92.6	Very high	88.1	Confident	14 Å²	14	45 Å²	45	7%	0.072	22%	0.216	C	C	.	.	I	π-helix	trans	-92.1	-61.1	-177.1	-54.5	-55.4	0	0	0	109.7	F133 F361 A369 F370	F133-I365 HydrophobicContact CB-CD1 3.72Å; F133-I365 HydrophobicContact CB-CG1 4.24Å; F133-I365 HydrophobicContact CD1-CD1 3.76Å; F133-I365 HydrophobicContact CD1-CG1 3.55Å; F133-I365 HydrophobicContact CD2-CG1 4.19Å; F133-I365 HydrophobicContact CE1-CG1 3.88Å; F133-I365 HydrophobicContact CE2-CG1 4.48Å; F133-I365 HydrophobicContact CG-CD1 3.76Å; F133-I365 HydrophobicContact CG-CG1 3.71Å; F133-I365 HydrophobicContact CZ-CG1 4.34Å; F361-I365 HydrophobicContact CD2-CB 4Å; F361-I365 HydrophobicContact CD2-CG1 4.16Å; F361-I365 HydrophobicContact CD2-CG2 4.13Å; F361-I365 HydrophobicContact CE2-CB 4.19Å; F361-I365 HydrophobicContact CE2-CG2 3.81Å; F361-I365 HydrophobicContact CG-CB 4.36Å; F361-I365 HydrophobicContact CZ-CG2 4.26Å; F361-I365 WeakPolarHBondContact O-CA 3.4Å; F361-I365 VanDerWaalsContact O-CB 3.3Å; F361-I365 WeakPolarHBondContact O-CB 3.27Å; F361-I365 PolarHBondContact O-N 3.38Å; F361-I365 VanDerWaalsContact O-N 3.09Å; I365-A369 WeakPolarHBondContact O-CA 3.3Å; I365-A369 WeakPolarHBondContact O-CB 3.37Å; I365-A369 PolarHBondContact O-N 2.94Å; I365-A369 VanDerWaalsContact O-N 3.1Å; I365-F370 HydrophobicContact CG2-CD2 3.73Å; I365-F370 HydrophobicContact CG2-CE2 3.44Å; I365-F370 VanDerWaalsContact CG2-CE2 3.44Å; I365-F370 WeakPolarHBondContact O-CD2 3.39Å; I365-F370 PolarHBondContact O-N 3.44Å; I365-F370 VanDerWaalsContact O-N 3.09Å
366	Y	91.3	Very high	87.7	Confident	56 Å²	56	46.9 Å²	46.9	22%	0.22	23%	0.226	C	C	.	.	I	π-helix	trans	-67.3	-60	-173.3	-168.4	-95.5	0	0	0	112.2	F361 A362 F370 R371 A374 E378 V382	F361-Y366 PolarHBondContact O-N 2.63Å; A362-Y366 WeakPolarHBondContact O-CB 3.27Å; Y366-F370 CarbonylContact O-C 3.57Å; Y366-F370 WeakPolarHBondContact O-CB 3.43Å; Y366-F370 PolarHBondContact O-N 3.22Å; Y366-R371 HydrophobicContact CE1-CB 4.26Å; Y366-R371 PolarHBondContact O-N 3.11Å; Y366-A374 HydrophobicContact CD1-CB 4.43Å; Y366-A374 HydrophobicContact CE1-CB 4.1Å; Y366-E378 HydrophobicContact CE1-CG 4.15Å; Y366-E378 PolarHBondContact OH-OE1 3.49Å; Y366-V382 HydrophobicContact CD1-CB 4.48Å; Y366-V382 HydrophobicContact CD1-CG1 4.38Å; Y366-V382 HydrophobicContact CD1-CG2 3.88Å; Y366-V382 HydrophobicContact CD2-CG1 4.19Å; Y366-V382 HydrophobicContact CD2-CG2 4.17Å; Y366-V382 HydrophobicContact CE1-CG2 3.72Å; Y366-V382 HydrophobicContact CE2-CG2 4.02Å; Y366-V382 HydrophobicContact CG-CG1 3.96Å; Y366-V382 HydrophobicContact CG-CG2 4.09Å
367	Q	85.1	Confident	87.3	Confident	27 Å²	27	50.1 Å²	50.1	13%	0.126	25%	0.246	C	C	.	.	I	π-helix	trans	-69.6	-54.1	-177.1	-173.5	-178.6	23.8	0	0	111.6	A362 R363 R371 Q372 I379	A362-Q367 WeakPolarHBondContact O-CB 3.42Å; A362-Q367 PolarHBondContact O-N 3.44Å; R363-Q367 WeakPolarHBondContact O-CB 3.48Å; Q367-R371 CarbonylContact O-C 3.27Å; Q367-Q372 WeakPolarHBondContact O-CA 3.4Å; Q367-Q372 PolarHBondContact O-N 2.82Å; Q367-Q372 VanDerWaalsContact O-N 3.13Å; Q367-I379 HydrophobicContact CB-CD1 4.3Å; Q367-I379 HydrophobicContact CG-CD1 3.99Å; Q367-I379 VanDerWaalsContact NE2-CD1 3.32Å
368	Q	81.6	Confident	87	Confident	41 Å²	41	51.6 Å²	51.6	19%	0.192	25%	0.253	C	S	.	.	I	π-helix	trans	-76.2	-35	-171.7	-70	-175.9	31	0	0	114.3	D118 K126 R363	D118-Q368 PolarHBondContact OD1-NE2 3.4Å; K126-Q368 VanDerWaalsContact CD-O 3.26Å; K126-Q368 WeakPolarHBondContact CD-O 3.44Å; K126-Q368 VanDerWaalsContact CE-O 3.22Å; K126-Q368 WeakPolarHBondContact CE-O 3.35Å; R363-Q368 WeakPolarHBondContact O-CG 3.45Å; R363-Q368 PolarHBondContact O-N 3.15Å
369	A	79.1	Confident	86.7	Confident	40 Å²	40	51.6 Å²	51.6	33%	0.331	25%	0.253	S	S	.	.	I	π-helix	trans	-97.1	-44.1	-176.5	0	0	0	0	0	113.6	I365	I365-A369 WeakPolarHBondContact O-CA 3.3Å; I365-A369 WeakPolarHBondContact O-CB 3.37Å; I365-A369 PolarHBondContact O-N 2.94Å; I365-A369 VanDerWaalsContact O-N 3.1Å
370	F	83.7	Confident	86.4	Confident	157 Å²	157	52 Å²	52	69%	0.689	26%	0.255	S	S	*	.	I	π-helix	trans	-94.8	-49.7	-173.8	-72.4	-72.9	0	0	0	114.6	I365 Y366	I365-F370 HydrophobicContact CG2-CD2 3.73Å; I365-F370 HydrophobicContact CG2-CE2 3.44Å; I365-F370 VanDerWaalsContact CG2-CE2 3.44Å; I365-F370 WeakPolarHBondContact O-CD2 3.39Å; I365-F370 PolarHBondContact O-N 3.44Å; I365-F370 VanDerWaalsContact O-N 3.09Å; Y366-F370 CarbonylContact O-C 3.57Å; Y366-F370 WeakPolarHBondContact O-CB 3.43Å; Y366-F370 PolarHBondContact O-N 3.22Å
371	R	86.1	Confident	86.2	Confident	128 Å²	128	59 Å²	59	48%	0.483	28%	0.281	S	S	.	.			trans	-136.2	82.7	-172.5	-164.8	-177.8	178.7	162.7	0.1	111.8	Y366 Q367 M373 A374 E378	Y366-R371 HydrophobicContact CE1-CB 4.26Å; Y366-R371 PolarHBondContact O-N 3.11Å; Q367-R371 CarbonylContact O-C 3.27Å; R371-M373 PolarHBondContact O-N 2.68Å; R371-M373 VanDerWaalsContact O-N 3.17Å; R371-A374 HydrophobicContact CB-CB 4.29Å; R371-A374 HydrophobicContact CG-CB 4.12Å; R371-A374 VanDerWaalsContact O-CB 3.23Å; R371-A374 WeakPolarHBondContact O-CB 3.38Å; R371-A374 PolarHBondContact O-N 3.35Å; R371-E378 WeakPolarHBondContact CD-OE1 3.39Å; R371-E378 IonicContact CZ-OE1 2.84Å; R371-E378 IonicContact CZ-OE2 3.41Å; R371-E378 VanDerWaalsContact CZ-OE2 3.27Å; R371-E378 IonicContact NE-OE1 2.83Å; R371-E378 PolarHBondContact NE-OE1 3.41Å; R371-E378 IonicContact NE-OE2 2.82Å; R371-E378 PolarHBondContact NE-OE2 3.06Å; R371-E378 VanDerWaalsContact NH1-CD 3.31Å; R371-E378 IonicContact NH1-OE1 2.98Å; R371-E378 PolarHBondContact NH1-OE1 3.28Å; R371-E378 IonicContact NH1-OE2 3.59Å; R371-E378 PolarHBondContact NH1-OE2 3.01Å; R371-E378 IonicContact NH2-OE2 3.99Å
372	Q	83	Confident	86	Confident	119 Å²	119	57.3 Å²	57.3	56%	0.556	28%	0.275	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63	-23.8	-176.9	-66.9	165.3	30.2	0	0	114	Q367	Q367-Q372 WeakPolarHBondContact O-CA 3.4Å; Q367-Q372 PolarHBondContact O-N 2.82Å; Q367-Q372 VanDerWaalsContact O-N 3.13Å
373	M	82.5	Confident	85.9	Confident	175 Å²	175	57.4 Å²	57.4	86%	0.862	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.6	21.5	177.4	-59.9	-67.6	-71.6	0	0	112.3	R371	R371-M373 PolarHBondContact O-N 2.68Å; R371-M373 VanDerWaalsContact O-N 3.17Å
374	A	83.3	Confident	85.9	Confident	11 Å²	11	58.9 Å²	58.9	9%	0.091	28%	0.281	C	S	.	.			trans	-64	135.3	176.9	0	0	0	0	0	110.5	Y366 R371 I379	Y366-A374 HydrophobicContact CD1-CB 4.43Å; Y366-A374 HydrophobicContact CE1-CB 4.1Å; R371-A374 HydrophobicContact CB-CB 4.29Å; R371-A374 HydrophobicContact CG-CB 4.12Å; R371-A374 VanDerWaalsContact O-CB 3.23Å; R371-A374 WeakPolarHBondContact O-CB 3.38Å; R371-A374 PolarHBondContact O-N 3.35Å; A374-I379 HydrophobicContact CB-CD1 4.47Å; A374-I379 HydrophobicContact CB-CG1 4.09Å
375	S	85.4	Confident	86	Confident	62 Å²	62	63.9 Å²	63.9	43%	0.434	31%	0.307	S	S	.	.			trans	-73.5	156.9	175.2	69.5	0	0	0	0	111.3	T377 E378 I379	S375-T377 VanDerWaalsContact C-N 3.27Å; S375-T377 PolarHBondContact O-N 3.25Å; S375-E378 PolarHBondContact N-OE2 3.49Å; S375-E378 VanDerWaalsContact O-CB 3.3Å; S375-E378 WeakPolarHBondContact O-CB 3.1Å; S375-E378 PolarHBondContact O-N 2.83Å; S375-E378 WeakPolarHBondContact OG-CB 3.35Å; S375-E378 PolarHBondContact OG-N 2.99Å; S375-I379 WeakPolarHBondContact O-CG1 3.28Å; S375-I379 PolarHBondContact O-N 3.34Å
376	D	80.9	Confident	86	Confident	41 Å²	41	63.8 Å²	63.8	22%	0.219	31%	0.307	C	S	.	.	H	α-helix	trans	-55.7	-42	175.7	-87.5	-23.4	0	0	0	113.5	D39 R40 S41 E378 I379 V380	D39-D376 VanDerWaalsContact CA-OD2 3.24Å; D39-D376 WeakPolarHBondContact CA-OD2 3.31Å; R40-D376 HydrophobicContact CB-CB 4.07Å; R40-D376 PolarHBondContact N-OD2 2.98Å; S41-D376 WeakPolarHBondContact CB-OD1 3.36Å; S41-D376 PolarHBondContact OG-OD1 3.29Å; D376-E378 PolarHBondContact O-N 3.46Å; D376-I379 PolarHBondContact O-N 3.4Å; D376-V380 VanDerWaalsContact O-CG2 3.29Å; D376-V380 WeakPolarHBondContact O-CG2 3.28Å; D376-V380 PolarHBondContact O-N 2.86Å
377	T	82.6	Confident	86	Confident	68 Å²	68	61.4 Å²	61.4	42%	0.417	30%	0.298	S	S	.	.	H	α-helix	trans	-61.4	-38.4	178.8	-58.1	0	0	0	0	111	S375 V380 W381	S375-T377 VanDerWaalsContact C-N 3.27Å; S375-T377 PolarHBondContact O-N 3.25Å; T377-V380 PolarHBondContact O-N 3.48Å; T377-W381 PolarHBondContact O-N 2.95Å; T377-W381 VanDerWaalsContact O-N 3.11Å
378	E	87.7	Confident	86.4	Confident	34 Å²	34	65.7 Å²	65.7	16%	0.159	32%	0.316	C	S	.	.	H	α-helix	trans	-66.4	-45.5	176.8	-176.3	-179.9	174	0	0	111.7	Y366 R371 S375 D376 V380 W381 V382	Y366-E378 HydrophobicContact CE1-CG 4.15Å; Y366-E378 PolarHBondContact OH-OE1 3.49Å; R371-E378 WeakPolarHBondContact CD-OE1 3.39Å; R371-E378 IonicContact CZ-OE1 2.84Å; R371-E378 IonicContact CZ-OE2 3.41Å; R371-E378 VanDerWaalsContact CZ-OE2 3.27Å; R371-E378 IonicContact NE-OE1 2.83Å; R371-E378 PolarHBondContact NE-OE1 3.41Å; R371-E378 IonicContact NE-OE2 2.82Å; R371-E378 PolarHBondContact NE-OE2 3.06Å; R371-E378 VanDerWaalsContact NH1-CD 3.31Å; R371-E378 IonicContact NH1-OE1 2.98Å; R371-E378 PolarHBondContact NH1-OE1 3.28Å; R371-E378 IonicContact NH1-OE2 3.59Å; R371-E378 PolarHBondContact NH1-OE2 3.01Å; R371-E378 IonicContact NH2-OE2 3.99Å; S375-E378 PolarHBondContact N-OE2 3.49Å; S375-E378 VanDerWaalsContact O-CB 3.3Å; S375-E378 WeakPolarHBondContact O-CB 3.1Å; S375-E378 PolarHBondContact O-N 2.83Å; S375-E378 WeakPolarHBondContact OG-CB 3.35Å; S375-E378 PolarHBondContact OG-N 2.99Å; D376-E378 PolarHBondContact O-N 3.46Å; E378-V380 VanDerWaalsContact C-N 3.26Å; E378-V380 PolarHBondContact O-N 3.16Å; E378-W381 PolarHBondContact O-N 3.45Å; E378-W381 VanDerWaalsContact O-N 3.12Å; E378-V382 WeakPolarHBondContact O-CG2 3.44Å; E378-V382 PolarHBondContact O-N 3.46Å
379	I	86	Confident	87	Confident	0 Å²	0	66.8 Å²	66.8	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-58.8	-41.1	176.6	-64	165.7	0	0	0	110.6	M45 A362 Q367 A374 S375 D376 W381 V382 M383	M45-I379 HydrophobicContact CE-CG2 3.59Å; A362-I379 HydrophobicContact CB-CG2 4.08Å; Q367-I379 HydrophobicContact CB-CD1 4.3Å; Q367-I379 HydrophobicContact CG-CD1 3.99Å; Q367-I379 VanDerWaalsContact NE2-CD1 3.32Å; A374-I379 HydrophobicContact CB-CD1 4.47Å; A374-I379 HydrophobicContact CB-CG1 4.09Å; S375-I379 WeakPolarHBondContact O-CG1 3.28Å; S375-I379 PolarHBondContact O-N 3.34Å; D376-I379 PolarHBondContact O-N 3.4Å; I379-W381 PolarHBondContact O-N 2.98Å; I379-V382 PolarHBondContact O-N 3.34Å; I379-M383 WeakPolarHBondContact O-CG 3.34Å; I379-M383 PolarHBondContact O-N 3.35Å
380	V	84.8	Confident	87.8	Confident	7 Å²	7	65.7 Å²	65.7	4%	0.042	31%	0.314	C	S	.	.	H	α-helix	trans	-63.7	-40.5	176.6	173.3	0	0	0	0	112.3	R40 I44 D376 T377 E378 M383 R384	R40-V380 HydrophobicContact CG-CG2 4.43Å; I44-V380 HydrophobicContact CD1-CB 4.27Å; I44-V380 HydrophobicContact CD1-CG1 3.78Å; I44-V380 HydrophobicContact CD1-CG2 3.42Å; I44-V380 VanDerWaalsContact CD1-CG2 3.42Å; D376-V380 VanDerWaalsContact O-CG2 3.29Å; D376-V380 WeakPolarHBondContact O-CG2 3.28Å; D376-V380 PolarHBondContact O-N 2.86Å; T377-V380 PolarHBondContact O-N 3.48Å; E378-V380 VanDerWaalsContact C-N 3.26Å; E378-V380 PolarHBondContact O-N 3.16Å; V380-M383 HydrophobicContact CB-CE 4.32Å; V380-M383 HydrophobicContact CG2-CE 3.9Å; V380-M383 PolarHBondContact O-N 3.36Å; V380-R384 WeakPolarHBondContact O-CG 3.46Å; V380-R384 PolarHBondContact O-N 3.17Å
381	W	87.9	Confident	88.2	Confident	150 Å²	150	58.2 Å²	58.2	57%	0.568	28%	0.281	S	S	*	.	H	α-helix	trans	-66.4	-40.4	174.7	-83.6	112.4	0	0	0	112.3	T377 E378 I379 M383 R384 I385	T377-W381 PolarHBondContact O-N 2.95Å; T377-W381 VanDerWaalsContact O-N 3.11Å; E378-W381 PolarHBondContact O-N 3.45Å; E378-W381 VanDerWaalsContact O-N 3.12Å; I379-W381 PolarHBondContact O-N 2.98Å; W381-M383 VanDerWaalsContact C-N 3.34Å; W381-M383 PolarHBondContact O-N 2.96Å; W381-R384 PolarHBondContact O-N 3.47Å; W381-I385 WeakPolarHBondContact O-CG1 3.34Å; W381-I385 PolarHBondContact O-N 2.94Å
382	V	91.8	Very high	88.5	Confident	18 Å²	18	54.2 Å²	54.2	11%	0.109	28%	0.275	C	S	.	.	H	α-helix	trans	-61.9	-42.9	174.9	173.8	0	0	0	0	110.9	F361 A362 Y366 E378 I379 R384 I385 T386	F361-V382 HydrophobicContact CD1-CG1 4.03Å; F361-V382 HydrophobicContact CE1-CG1 4.05Å; A362-V382 HydrophobicContact CB-CG1 4.14Å; Y366-V382 HydrophobicContact CD1-CB 4.48Å; Y366-V382 HydrophobicContact CD1-CG1 4.38Å; Y366-V382 HydrophobicContact CD1-CG2 3.88Å; Y366-V382 HydrophobicContact CD2-CG1 4.19Å; Y366-V382 HydrophobicContact CD2-CG2 4.17Å; Y366-V382 HydrophobicContact CE1-CG2 3.72Å; Y366-V382 HydrophobicContact CE2-CG2 4.02Å; Y366-V382 HydrophobicContact CG-CG1 3.96Å; Y366-V382 HydrophobicContact CG-CG2 4.09Å; E378-V382 WeakPolarHBondContact O-CG2 3.44Å; E378-V382 PolarHBondContact O-N 3.46Å; I379-V382 PolarHBondContact O-N 3.34Å; V382-R384 PolarHBondContact O-N 2.91Å; V382-I385 PolarHBondContact O-N 3.38Å; V382-T386 HydrophobicContact CG1-CG2 4.34Å; V382-T386 WeakPolarHBondContact O-CB 3.16Å; V382-T386 VanDerWaalsContact O-CG2 3.29Å; V382-T386 WeakPolarHBondContact O-CG2 3.15Å; V382-T386 PolarHBondContact O-N 3.03Å; V382-T386 PolarHBondContact O-OG1 2.88Å
383	M	88.4	Confident	89	Confident	3 Å²	3	52.6 Å²	52.6	2%	0.015	27%	0.27	C	S	.	.	H	α-helix	trans	-57.8	-48.1	173.1	-74.4	-168.4	-64.9	0	0	111.5	I44 M45 A362 I379 V380 W381 I385 T386 I387	I44-M383 HydrophobicContact CB-CE 3.97Å; I44-M383 HydrophobicContact CG2-CE 3.47Å; I44-M383 VanDerWaalsContact CG2-CE 3.47Å; I44-M383 HydrophobicContact CG2-SD 4.23Å; M45-M383 HydrophobicContact CE-CE 4.09Å; M45-M383 HydrophobicContact CE-CG 4.05Å; M45-M383 HydrophobicContact CE-SD 3.33Å; M45-M383 WeakPolarHBondContact CE-SD 3.31Å; M45-M383 HydrophobicContact CG-CE 4.29Å; M45-M383 HydrophobicContact CG-SD 3.58Å; M45-M383 VanDerWaalsContact CG-SD 3.58Å; M45-M383 HydrophobicContact SD-SD 4.32Å; A362-M383 HydrophobicContact CB-CB 4.41Å; A362-M383 HydrophobicContact CB-CG 3.29Å; A362-M383 HydrophobicContact CB-SD 4.42Å; I379-M383 WeakPolarHBondContact O-CG 3.34Å; I379-M383 PolarHBondContact O-N 3.35Å; V380-M383 HydrophobicContact CB-CE 4.32Å; V380-M383 HydrophobicContact CG2-CE 3.9Å; V380-M383 PolarHBondContact O-N 3.36Å; W381-M383 VanDerWaalsContact C-N 3.34Å; W381-M383 PolarHBondContact O-N 2.96Å; M383-I385 PolarHBondContact O-N 2.84Å; M383-T386 WeakPolarHBondContact CA-OG1 3.42Å; M383-T386 PolarHBondContact O-N 3.4Å; M383-T386 PolarHBondContact O-OG1 3.46Å; M383-I387 VanDerWaalsContact O-CG1 3.26Å; M383-I387 WeakPolarHBondContact O-CG1 3.41Å; M383-I387 PolarHBondContact O-N 2.84Å
384	R	88.9	Confident	89.4	Confident	86 Å²	86	44.3 Å²	44.3	33%	0.325	23%	0.229	S	C	.	.	H	α-helix	trans	-62.1	-43.5	179.3	-73.7	174.7	171.3	-174.4	-3.1	113	L179 V380 W381 V382 T386 I387 F388	L179-R384 HydrophobicContact CD2-CB 3.96Å; L179-R384 HydrophobicContact CD2-CG 4.3Å; L179-R384 WeakPolarHBondContact CD2-O 3.36Å; L179-R384 PolarHBondContact O-NE 3.41Å; V380-R384 WeakPolarHBondContact O-CG 3.46Å; V380-R384 PolarHBondContact O-N 3.17Å; W381-R384 PolarHBondContact O-N 3.47Å; V382-R384 PolarHBondContact O-N 2.91Å; R384-T386 VanDerWaalsContact C-N 3.33Å; R384-T386 PolarHBondContact O-N 3.31Å; R384-I387 PolarHBondContact O-N 3.44Å; R384-F388 PolarHBondContact O-N 3.05Å
385	I	92.9	Very high	89.8	Confident	104 Å²	104	44.5 Å²	44.5	53%	0.533	23%	0.229	S	C	.	.	H	α-helix	trans	-62.9	-44.7	177.1	-68.1	165.6	0	0	0	110	W381 V382 M383 I387 F388 V389	W381-I385 WeakPolarHBondContact O-CG1 3.34Å; W381-I385 PolarHBondContact O-N 2.94Å; V382-I385 PolarHBondContact O-N 3.38Å; M383-I385 PolarHBondContact O-N 2.84Å; I385-I387 PolarHBondContact O-N 3.03Å; I385-F388 PolarHBondContact O-N 3.44Å; I385-V389 HydrophobicContact CG2-CG2 4.36Å; I385-V389 WeakPolarHBondContact O-CG2 3.48Å; I385-V389 PolarHBondContact O-N 3.15Å
386	T	93.4	Very high	90.1	Very high	12 Å²	12	43.7 Å²	43.7	7%	0.074	23%	0.226	C	C	.	.	H	α-helix	trans	-70.1	-30.1	-179.3	53.7	0	0	0	0	113.1	S358 F361 V382 M383 R384 F388 V389 F390	S358-T386 WeakPolarHBondContact CB-OG1 3.28Å; S358-T386 PolarHBondContact OG-OG1 3.28Å; S358-T386 VanDerWaalsContact OG-OG1 3.1Å; F361-T386 HydrophobicContact CD1-CG2 3.51Å; F361-T386 HydrophobicContact CE1-CG2 3.85Å; F361-T386 HydrophobicContact CG-CG2 4.12Å; V382-T386 HydrophobicContact CG1-CG2 4.34Å; V382-T386 WeakPolarHBondContact O-CB 3.16Å; V382-T386 VanDerWaalsContact O-CG2 3.29Å; V382-T386 WeakPolarHBondContact O-CG2 3.15Å; V382-T386 PolarHBondContact O-N 3.03Å; V382-T386 PolarHBondContact O-OG1 2.88Å; M383-T386 WeakPolarHBondContact CA-OG1 3.42Å; M383-T386 PolarHBondContact O-N 3.4Å; M383-T386 PolarHBondContact O-OG1 3.46Å; R384-T386 VanDerWaalsContact C-N 3.33Å; R384-T386 PolarHBondContact O-N 3.31Å; T386-F388 VanDerWaalsContact C-N 3.28Å; T386-F388 PolarHBondContact O-N 3.44Å; T386-V389 PolarHBondContact O-N 2.87Å; T386-F390 HydrophobicContact CG2-CE2 4.33Å; T386-F390 HydrophobicContact CG2-CZ 4.44Å; T386-F390 WeakPolarHBondContact O-CB 3.48Å; T386-F390 WeakPolarHBondContact O-CD2 3.17Å; T386-F390 WeakPolarHBondContact O-CG 3.46Å; T386-F390 PolarHBondContact O-N 3.22Å
387	I	91.9	Very high	90.3	Very high	6 Å²	6	44.3 Å²	44.3	3%	0.031	23%	0.228	C	C	.	.	H	α-helix	trans	-57.4	-47.1	171.9	-75.9	164.9	0	0	0	109.3	I175 T178 L179 I354 L355 S358 M383 R384 I385 G391	I175-I387 HydrophobicContact CG2-CG2 4.33Å; T178-I387 HydrophobicContact CG2-CD1 4.19Å; T178-I387 HydrophobicContact CG2-CG1 4.46Å; T178-I387 HydrophobicContact CG2-CG2 4.08Å; L179-I387 HydrophobicContact CD2-CB 3.81Å; L179-I387 HydrophobicContact CD2-CD1 4.4Å; L179-I387 HydrophobicContact CD2-CG2 3.63Å; L179-I387 HydrophobicContact CG-CG2 3.84Å; I354-I387 HydrophobicContact CG2-CB 4.05Å; I354-I387 HydrophobicContact CG2-CG1 4.17Å; I354-I387 HydrophobicContact CG2-CG2 3.76Å; I354-I387 WeakPolarHBondContact CG2-O 3.43Å; L355-I387 HydrophobicContact CD1-CD1 4.34Å; S358-I387 VanDerWaalsContact OG-CA 3.28Å; S358-I387 WeakPolarHBondContact OG-CA 3.39Å; S358-I387 VanDerWaalsContact OG-CG1 3.31Å; S358-I387 WeakPolarHBondContact OG-CG1 3.22Å; S358-I387 PolarHBondContact OG-N 2.91Å; M383-I387 VanDerWaalsContact O-CG1 3.26Å; M383-I387 WeakPolarHBondContact O-CG1 3.41Å; M383-I387 PolarHBondContact O-N 2.84Å; R384-I387 PolarHBondContact O-N 3.44Å; I385-I387 PolarHBondContact O-N 3.03Å; I387-G391 PolarHBondContact O-N 3.49Å
388	F	93.1	Very high	90.4	Very high	118 Å²	118	41.4 Å²	41.4	52%	0.518	21%	0.211	S	C	.	.	H	α-helix	trans	-64.7	-45.7	177	-177.9	-94.5	0	0	0	112	I175 R384 I385 T386 A392	I175-F388 HydrophobicContact CG2-CD2 4.11Å; R384-F388 PolarHBondContact O-N 3.05Å; I385-F388 PolarHBondContact O-N 3.44Å; T386-F388 VanDerWaalsContact C-N 3.28Å; T386-F388 PolarHBondContact O-N 3.44Å; F388-A392 VanDerWaalsContact O-CB 3.24Å; F388-A392 WeakPolarHBondContact O-CB 3.46Å; F388-A392 PolarHBondContact O-N 2.92Å
389	V	94.7	Very high	90.3	Very high	64 Å²	64	42.9 Å²	42.9	39%	0.388	22%	0.22	S	C	.	.	H	α-helix	trans	-64.2	-49.9	-179.1	172.4	0	0	0	0	111.9	I385 T386 A392 L393	I385-V389 HydrophobicContact CG2-CG2 4.36Å; I385-V389 WeakPolarHBondContact O-CG2 3.48Å; I385-V389 PolarHBondContact O-N 3.15Å; T386-V389 PolarHBondContact O-N 2.87Å; V389-A392 PolarHBondContact O-N 3.48Å; V389-L393 HydrophobicContact CG1-CD1 4.12Å; V389-L393 WeakPolarHBondContact O-CG 3.26Å; V389-L393 PolarHBondContact O-N 3.44Å
390	F	94.3	Very high	90	Very high	17 Å²	17	49.6 Å²	49.6	8%	0.075	25%	0.254	C	S	.	.	H	α-helix	trans	-69.8	-36.9	-179.5	-62	-32.1	0	0	0	111.8	F133 L137 I141 A357 F361 T386 L393 A394	F133-F390 HydrophobicContact CZ-CZ 4.37Å; L137-F390 HydrophobicContact CD1-CD1 3.99Å; L137-F390 HydrophobicContact CD1-CD2 4.13Å; L137-F390 HydrophobicContact CD1-CE1 3.76Å; L137-F390 HydrophobicContact CD1-CE2 3.88Å; L137-F390 HydrophobicContact CD1-CG 4.19Å; L137-F390 HydrophobicContact CD1-CZ 3.7Å; L137-F390 HydrophobicContact CD2-CE1 3.87Å; L137-F390 HydrophobicContact CD2-CZ 4.1Å; L137-F390 HydrophobicContact CG-CE1 4.45Å; I141-F390 HydrophobicContact CD1-CD1 4.37Å; A357-F390 HydrophobicContact CB-CD2 3.68Å; A357-F390 HydrophobicContact CB-CE2 4.13Å; A357-F390 HydrophobicContact CB-CG 4.37Å; F361-F390 HydrophobicContact CB-CE2 3.91Å; F361-F390 HydrophobicContact CB-CZ 4.03Å; F361-F390 HydrophobicContact CD2-CZ 4.06Å; F361-F390 HydrophobicContact CG-CE2 4.41Å; F361-F390 HydrophobicContact CG-CZ 4.12Å; T386-F390 HydrophobicContact CG2-CE2 4.33Å; T386-F390 HydrophobicContact CG2-CZ 4.44Å; T386-F390 WeakPolarHBondContact O-CB 3.48Å; T386-F390 WeakPolarHBondContact O-CD2 3.17Å; T386-F390 WeakPolarHBondContact O-CG 3.46Å; T386-F390 PolarHBondContact O-N 3.22Å; F390-L393 HydrophobicContact CD1-CD1 4.22Å; F390-L393 PolarHBondContact O-N 3.01Å; F390-A394 WeakPolarHBondContact O-CB 3.43Å; F390-A394 PolarHBondContact O-N 3.44Å
391	G	92.6	Very high	89.1	Confident	0 Å²	0	50.9 Å²	50.9	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-61.4	-42.8	170.9	0	0	0	0	0	112.6	I387 A394 T395	I387-G391 PolarHBondContact O-N 3.49Å; G391-A394 PolarHBondContact O-N 2.94Å; G391-T395 WeakPolarHBondContact O-CB 3.26Å; G391-T395 PolarHBondContact O-N 3.2Å; G391-T395 PolarHBondContact O-OG1 3.45Å
392	A	92.9	Very high	87.6	Confident	43 Å²	43	48.1 Å²	48.1	36%	0.355	28%	0.28	S	S	.	.	H	α-helix	trans	-65.4	-40.5	175.4	0	0	0	0	0	112.2	F388 V389 T395 A396	F388-A392 VanDerWaalsContact O-CB 3.24Å; F388-A392 WeakPolarHBondContact O-CB 3.46Å; F388-A392 PolarHBondContact O-N 2.92Å; V389-A392 PolarHBondContact O-N 3.48Å; A392-T395 PolarHBondContact O-N 3.43Å; A392-A396 WeakPolarHBondContact O-CB 3.25Å; A392-A396 PolarHBondContact O-N 3.43Å
393	L	92.9	Very high	86.3	Confident	86 Å²	86	49.4 Å²	49.4	45%	0.45	29%	0.29	S	S	.	.	H	α-helix	trans	-64	-44.9	174.6	-73.9	171.8	0	0	0	111.9	I141 V389 F390 T395 A396 M397	I141-L393 HydrophobicContact CD1-CD1 4.32Å; V389-L393 HydrophobicContact CG1-CD1 4.12Å; V389-L393 WeakPolarHBondContact O-CG 3.26Å; V389-L393 PolarHBondContact O-N 3.44Å; F390-L393 HydrophobicContact CD1-CD1 4.22Å; F390-L393 PolarHBondContact O-N 3.01Å; L393-T395 VanDerWaalsContact C-N 3.3Å; L393-T395 PolarHBondContact O-N 3.3Å; L393-A396 PolarHBondContact O-N 3.38Å; L393-M397 WeakPolarHBondContact O-CB 3.22Å; L393-M397 WeakPolarHBondContact O-CG 3.41Å; L393-M397 PolarHBondContact O-N 3.16Å
394	A	91.8	Very high	85.1	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-61.7	-39.8	174.9	0	0	0	0	0	111.6	A145 L148 F390 G391 M397 A398	A145-A394 WeakPolarHBondContact CA-O 3.46Å; A145-A394 HydrophobicContact CB-CB 4.41Å; A145-A394 VanDerWaalsContact CB-O 3.23Å; A145-A394 WeakPolarHBondContact CB-O 3.44Å; L148-A394 HydrophobicContact CD1-CB 4.08Å; F390-A394 WeakPolarHBondContact O-CB 3.43Å; F390-A394 PolarHBondContact O-N 3.44Å; G391-A394 PolarHBondContact O-N 2.94Å; A394-M397 PolarHBondContact O-N 3.29Å; A394-A398 WeakPolarHBondContact O-CB 3.45Å; A394-A398 PolarHBondContact O-N 2.92Å
395	T	91.3	Very high	83.8	Confident	16 Å²	16	47.6 Å²	47.6	10%	0.098	29%	0.286	C	S	.	.	H	α-helix	trans	-64.6	-46.3	175.4	-53.4	0	0	0	0	111.4	V167 V168 A171 G391 A392 L393 M397 A398 L399	V167-T395 HydrophobicContact CG1-CG2 4.37Å; V168-T395 HydrophobicContact CG2-CG2 4.48Å; A171-T395 HydrophobicContact CB-CG2 3.86Å; A171-T395 WeakPolarHBondContact CB-OG1 3.47Å; G391-T395 WeakPolarHBondContact O-CB 3.26Å; G391-T395 PolarHBondContact O-N 3.2Å; G391-T395 PolarHBondContact O-OG1 3.45Å; A392-T395 PolarHBondContact O-N 3.43Å; L393-T395 VanDerWaalsContact C-N 3.3Å; L393-T395 PolarHBondContact O-N 3.3Å; T395-M397 VanDerWaalsContact C-N 3.31Å; T395-M397 PolarHBondContact O-N 3.1Å; T395-A398 WeakPolarHBondContact O-CB 3.4Å; T395-A398 PolarHBondContact O-N 3.42Å; T395-L399 HydrophobicContact CG2-CD1 4.24Å; T395-L399 VanDerWaalsContact O-CG 3.31Å; T395-L399 WeakPolarHBondContact O-CG 3.03Å; T395-L399 PolarHBondContact O-N 3.22Å
396	A	91	Very high	82.5	Confident	44 Å²	44	42.7 Å²	42.7	36%	0.364	26%	0.261	S	S	.	.	H	α-helix	trans	-59.5	-44.8	176.7	0	0	0	0	0	110.7	A392 L393 L399 L400	A392-A396 WeakPolarHBondContact O-CB 3.25Å; A392-A396 PolarHBondContact O-N 3.43Å; L393-A396 PolarHBondContact O-N 3.38Å; A396-L399 PolarHBondContact O-N 3.49Å; A396-L400 WeakPolarHBondContact O-CB 3.39Å; A396-L400 WeakPolarHBondContact O-CG 2.92Å; A396-L400 PolarHBondContact O-N 3.33Å
397	M	85.8	Confident	81.3	Confident	55 Å²	55	42.3 Å²	42.3	27%	0.271	26%	0.259	S	S	.	.	H	α-helix	trans	-60.3	-47.7	174.4	-72.7	-58.9	-59.4	0	0	111.7	I141 F142 A145 L393 A394 T395 L399 L400 T401 L407	I141-M397 HydrophobicContact CG2-CG 4.31Å; F142-M397 HydrophobicContact CD1-CE 4.49Å; F142-M397 HydrophobicContact CE1-CE 4.15Å; A145-M397 HydrophobicContact CB-CB 3.72Å; L393-M397 WeakPolarHBondContact O-CB 3.22Å; L393-M397 WeakPolarHBondContact O-CG 3.41Å; L393-M397 PolarHBondContact O-N 3.16Å; A394-M397 PolarHBondContact O-N 3.29Å; T395-M397 VanDerWaalsContact C-N 3.31Å; T395-M397 PolarHBondContact O-N 3.1Å; M397-L399 PolarHBondContact O-N 3.46Å; M397-L400 PolarHBondContact O-N 2.79Å; M397-T401 HydrophobicContact CE-CG2 3.89Å; M397-T401 WeakPolarHBondContact O-CG2 2.96Å; M397-T401 PolarHBondContact O-N 3.26Å; M397-T401 PolarHBondContact O-OG1 3.43Å; M397-L407 HydrophobicContact CE-CD2 4.18Å
398	A	85.1	Confident	80.1	Confident	6 Å²	6	43 Å²	43	5%	0.05	26%	0.261	C	S	.	.	H	α-helix	trans	-56.7	-35.2	178.1	0	0	0	0	0	113.2	A145 L148 V167 A394 T395	A145-A398 HydrophobicContact CB-CB 4.3Å; A145-A398 WeakPolarHBondContact O-CB 3.44Å; L148-A398 HydrophobicContact CB-CB 4.33Å; V167-A398 HydrophobicContact CG1-CB 3.95Å; A394-A398 WeakPolarHBondContact O-CB 3.45Å; A394-A398 PolarHBondContact O-N 2.92Å; T395-A398 WeakPolarHBondContact O-CB 3.4Å; T395-A398 PolarHBondContact O-N 3.42Å
399	L	84.9	Confident	78.8	Confident	66 Å²	66	38 Å²	38	35%	0.346	24%	0.238	S	C	.	.	H	α-helix	trans	-79.6	-28.1	177.3	-66.7	173.6	0	0	0	113.4	N164 V167 V168 T395 A396 M397	N164-L399 HydrophobicContact CB-CD2 3.77Å; V167-L399 HydrophobicContact CB-CD2 3.99Å; V167-L399 HydrophobicContact CG1-CD2 3.99Å; V167-L399 HydrophobicContact CG1-CG 4.29Å; V168-L399 HydrophobicContact CG2-CD1 3.92Å; V168-L399 HydrophobicContact CG2-CD2 4.47Å; T395-L399 HydrophobicContact CG2-CD1 4.24Å; T395-L399 VanDerWaalsContact O-CG 3.31Å; T395-L399 WeakPolarHBondContact O-CG 3.03Å; T395-L399 PolarHBondContact O-N 3.22Å; A396-L399 PolarHBondContact O-N 3.49Å; M397-L399 PolarHBondContact O-N 3.46Å
400	L	79.1	Confident	77.8	Confident	140 Å²	140	35.5 Å²	35.5	73%	0.733	22%	0.223	S	C	*	.	H	α-helix	trans	-86.2	-27.7	-178.8	-70	171.5	0	0	0	112.6	A396 M397	A396-L400 WeakPolarHBondContact O-CB 3.39Å; A396-L400 WeakPolarHBondContact O-CG 2.92Å; A396-L400 PolarHBondContact O-N 3.33Å; M397-L400 PolarHBondContact O-N 2.79Å
401	T	65.7	Low	76.8	Confident	34 Å²	34	34.7 Å²	34.7	21%	0.209	22%	0.219	C	C	.	.			trans	-100.7	117.6	-177.7	60.9	0	0	0	0	111	M397 S403 L407	M397-T401 HydrophobicContact CE-CG2 3.89Å; M397-T401 WeakPolarHBondContact O-CG2 2.96Å; M397-T401 PolarHBondContact O-N 3.26Å; M397-T401 PolarHBondContact O-OG1 3.43Å; T401-S403 PolarHBondContact O-N 2.9Å; T401-S403 VanDerWaalsContact O-N 3.14Å; T401-L407 HydrophobicContact CG2-CD1 4.39Å; T401-L407 HydrophobicContact CG2-CD2 3.87Å; T401-L407 HydrophobicContact CG2-CG 4.13Å; T401-L407 WeakPolarHBondContact OG1-CD1 3.27Å; T401-L407 WeakPolarHBondContact OG1-CG 3.35Å
402	G	57.1	Low	76.1	Confident	92 Å²	92	34.7 Å²	34.7	95%	0.948	22%	0.22	S	C	*	.	S	Bend	trans	-75.6	13.2	176.4	0	0	0	0	0	115.4
403	S	63.9	Low	75.7	Confident	45 Å²	45	32.9 Å²	32.9	32%	0.315	20%	0.204	S	C	.	.			trans	-140.3	109.2	-179.6	-177.3	0	0	0	0	112	T401 Y405 G406 L407	T401-S403 PolarHBondContact O-N 2.9Å; T401-S403 VanDerWaalsContact O-N 3.14Å; S403-Y405 VanDerWaalsContact C-N 3.28Å; S403-Y405 PolarHBondContact O-N 2.78Å; S403-G406 PolarHBondContact O-N 3.15Å; S403-G406 PolarHBondContact OG-N 2.94Å; S403-G406 VanDerWaalsContact OG-N 3.11Å; S403-L407 PolarHBondContact O-N 3.44Å
404	V	63.3	Low	75.4	Confident	20 Å²	20	30 Å²	30	12%	0.121	19%	0.189	C	C	.	.	H	α-helix	trans	-55.4	-46.5	170.6	174.1	0	0	0	0	110.5	A146 S149 A150 L407 W408	A146-V404 HydrophobicContact CB-CG1 4.2Å; A146-V404 WeakPolarHBondContact CB-O 3.41Å; A146-V404 WeakPolarHBondContact O-CG1 3.45Å; S149-V404 VanDerWaalsContact OG-CG2 3.28Å; S149-V404 WeakPolarHBondContact OG-CG2 3.2Å; A150-V404 HydrophobicContact CB-CG1 4.15Å; V404-L407 PolarHBondContact O-N 3.07Å; V404-W408 WeakPolarHBondContact O-CB 3.21Å; V404-W408 PolarHBondContact O-N 3.09Å
405	Y	61.3	Low	75.4	Confident	31 Å²	31	30.2 Å²	30.2	12%	0.122	19%	0.19	C	C	.	.	H	α-helix	trans	-66.5	-43.7	-176.4	180	-97.7	0	0	0	112.5	Y76 S403 L407 W408 Y409 Y455	Y76-Y405 AromaticContact CE2-CD2 3.84Å; Y76-Y405 HydrophobicContact CE2-CD2 3.84Å; Y76-Y405 AromaticContact CE2-CE2 3.37Å; Y76-Y405 HydrophobicContact CE2-CE2 3.37Å; Y76-Y405 AromaticContact CE2-CZ 3.83Å; Y76-Y405 AromaticContact CZ-CE2 3.79Å; Y76-Y405 AromaticContact CZ-CZ 3.73Å; Y76-Y405 WeakPolarHBondContact OH-CE1 3.37Å; Y76-Y405 WeakPolarHBondContact OH-CE2 3.34Å; Y76-Y405 PolarHBondContact OH-OH 3.23Å; S403-Y405 VanDerWaalsContact C-N 3.28Å; S403-Y405 PolarHBondContact O-N 2.78Å; Y405-L407 VanDerWaalsContact C-N 3.32Å; Y405-L407 PolarHBondContact O-N 3.42Å; Y405-W408 AromaticContact CD2-CE3 3.99Å; Y405-W408 HydrophobicContact CD2-CE3 3.99Å; Y405-W408 HydrophobicContact CD2-CZ3 4.48Å; Y405-W408 AromaticContact CE2-CE3 3.75Å; Y405-W408 HydrophobicContact CE2-CE3 3.75Å; Y405-W408 AromaticContact CE2-CZ3 3.89Å; Y405-W408 HydrophobicContact CE2-CZ3 3.89Å; Y405-W408 PolarHBondContact O-N 2.92Å; Y405-W408 VanDerWaalsContact O-N 3.15Å; Y405-Y409 HydrophobicContact CE1-CD2 4.44Å; Y405-Y409 WeakPolarHBondContact O-CB 3.39Å; Y405-Y409 PolarHBondContact O-N 3.13Å; Y405-Y455 HydrophobicContact CD1-CE1 4.35Å; Y405-Y455 AromaticContact CD1-CZ 3.91Å; Y405-Y455 WeakPolarHBondContact CD1-OH 3.5Å; Y405-Y455 HydrophobicContact CE1-CE2 4.37Å; Y405-Y455 AromaticContact CE1-CZ 3.96Å; Y405-Y455 VanDerWaalsContact CE1-OH 3.3Å; Y405-Y455 WeakPolarHBondContact CE1-OH 3.39Å
406	G	65.8	Low	75.5	Confident	2 Å²	2	29.5 Å²	29.5	2%	0.021	19%	0.186	C	C	.	.	H	α-helix	trans	-57.4	-46.7	177.2	0	0	0	0	0	111.6	S403 Y409 L410	S403-G406 PolarHBondContact O-N 3.15Å; S403-G406 PolarHBondContact OG-N 2.94Å; S403-G406 VanDerWaalsContact OG-N 3.11Å; G406-Y409 PolarHBondContact O-N 3.11Å; G406-L410 WeakPolarHBondContact O-CB 3.28Å; G406-L410 WeakPolarHBondContact O-CD1 3.36Å; G406-L410 WeakPolarHBondContact O-CG 3.3Å; G406-L410 PolarHBondContact O-N 3.26Å
407	L	67.9	Low	75.7	Confident	4 Å²	4	27.4 Å²	27.4	2%	0.021	17%	0.168	C	C	.	.	H	α-helix	trans	-60.2	-45.7	173.9	-78.5	177.4	0	0	0	112.7	F142 A145 A146 M397 T401 S403 V404 Y405 Y409 L410 S411	F142-L407 HydrophobicContact CD1-CD2 4.22Å; A145-L407 HydrophobicContact CB-CD1 3.52Å; A145-L407 HydrophobicContact CB-CD2 4.32Å; A145-L407 HydrophobicContact CB-CG 4.48Å; A146-L407 HydrophobicContact CB-CB 3.85Å; M397-L407 HydrophobicContact CE-CD2 4.18Å; T401-L407 HydrophobicContact CG2-CD1 4.39Å; T401-L407 HydrophobicContact CG2-CD2 3.87Å; T401-L407 HydrophobicContact CG2-CG 4.13Å; T401-L407 WeakPolarHBondContact OG1-CD1 3.27Å; T401-L407 WeakPolarHBondContact OG1-CG 3.35Å; S403-L407 PolarHBondContact O-N 3.44Å; V404-L407 PolarHBondContact O-N 3.07Å; Y405-L407 VanDerWaalsContact C-N 3.32Å; Y405-L407 PolarHBondContact O-N 3.42Å; L407-Y409 VanDerWaalsContact C-N 3.33Å; L407-Y409 PolarHBondContact O-N 2.91Å; L407-L410 PolarHBondContact O-N 2.86Å; L407-S411 PolarHBondContact O-N 3.48Å
408	W	66.9	Low	76.1	Confident	19 Å²	19	24.8 Å²	24.8	7%	0.072	16%	0.156	C	C	.	.	H	α-helix	trans	-61.6	-43.1	179.5	-176.8	68.6	0	0	0	111.9	A89 Y93 W143 A146 L249 V404 Y405 S411	A89-W408 HydrophobicContact CB-CH2 3.67Å; A89-W408 HydrophobicContact CB-CZ2 4.27Å; Y93-W408 AromaticContact CE2-CH2 3.87Å; Y93-W408 HydrophobicContact CE2-CH2 3.87Å; Y93-W408 AromaticContact CE2-CZ2 3.44Å; Y93-W408 HydrophobicContact CE2-CZ2 3.44Å; Y93-W408 VanDerWaalsContact CE2-CZ2 3.44Å; Y93-W408 AromaticContact CZ-CZ2 3.82Å; Y93-W408 VanDerWaalsContact OH-CZ2 3.28Å; Y93-W408 WeakPolarHBondContact OH-CZ2 3.08Å; W143-W408 AromaticContact CD1-CD1 3.64Å; W143-W408 AromaticContact NE1-CD1 3.89Å; W143-W408 AromaticContact NE1-NE1 3.91Å; A146-W408 HydrophobicContact CB-CB 3.89Å; L249-W408 HydrophobicContact CD2-CH2 3.81Å; L249-W408 HydrophobicContact CD2-CZ2 4.43Å; L249-W408 HydrophobicContact CD2-CZ3 4.26Å; V404-W408 WeakPolarHBondContact O-CB 3.21Å; V404-W408 PolarHBondContact O-N 3.09Å; Y405-W408 AromaticContact CD2-CE3 3.99Å; Y405-W408 HydrophobicContact CD2-CE3 3.99Å; Y405-W408 HydrophobicContact CD2-CZ3 4.48Å; Y405-W408 AromaticContact CE2-CE3 3.75Å; Y405-W408 HydrophobicContact CE2-CE3 3.75Å; Y405-W408 AromaticContact CE2-CZ3 3.89Å; Y405-W408 HydrophobicContact CE2-CZ3 3.89Å; Y405-W408 PolarHBondContact O-N 2.92Å; Y405-W408 VanDerWaalsContact O-N 3.15Å; W408-S411 WeakPolarHBondContact O-CB 3.29Å; W408-S411 PolarHBondContact O-N 3.31Å; W408-S411 PolarHBondContact O-OG 3.26Å
409	Y	67.6	Low	76.5	Confident	13 Å²	13	24.6 Å²	24.6	5%	0.051	15%	0.153	C	C	.	.	H	α-helix	trans	-64.9	-47.4	176.9	-170.5	-80.8	0	0	0	111.7	N245 L248 Y405 G406 L407 S411 S412 D413 K491	N245-Y409 WeakPolarHBondContact OD1-CE2 3.24Å; N245-Y409 PolarHBondContact OD1-OH 3.32Å; L248-Y409 HydrophobicContact CD1-CE1 4.16Å; Y405-Y409 HydrophobicContact CE1-CD2 4.44Å; Y405-Y409 WeakPolarHBondContact O-CB 3.39Å; Y405-Y409 PolarHBondContact O-N 3.13Å; G406-Y409 PolarHBondContact O-N 3.11Å; L407-Y409 VanDerWaalsContact C-N 3.33Å; L407-Y409 PolarHBondContact O-N 2.91Å; Y409-S411 PolarHBondContact O-N 3.01Å; Y409-S412 PolarHBondContact O-N 2.83Å; Y409-D413 HydrophobicContact CE1-CB 4.48Å; Y409-D413 PolarHBondContact O-N 3.46Å; Y409-K491 HydrophobicContact CE1-CD 4.32Å; Y409-K491 WeakPolarHBondContact OH-CD 3.41Å; Y409-K491 WeakPolarHBondContact OH-CE 3.18Å; Y409-K491 PolarHBondContact OH-NZ 3.35Å
410	L	72.1	Confident	77.1	Confident	12 Å²	12	21.9 Å²	21.9	6%	0.063	14%	0.139	C	C	.	.	H	α-helix	trans	-58.4	-30.8	177.1	-71.3	168.1	0	0	0	112.7	F142 G406 L407 S412 D413 E453 L456	F142-L410 HydrophobicContact CD2-CB 3.8Å; F142-L410 HydrophobicContact CE2-CB 4.21Å; F142-L410 HydrophobicContact CG-CB 4.44Å; G406-L410 WeakPolarHBondContact O-CB 3.28Å; G406-L410 WeakPolarHBondContact O-CD1 3.36Å; G406-L410 WeakPolarHBondContact O-CG 3.3Å; G406-L410 PolarHBondContact O-N 3.26Å; L407-L410 PolarHBondContact O-N 2.86Å; L410-S412 VanDerWaalsContact C-N 3.33Å; L410-S412 PolarHBondContact O-N 3.4Å; L410-D413 PolarHBondContact O-N 3.27Å; L410-E453 HydrophobicContact CD2-CG 3.63Å; L410-L456 HydrophobicContact CD1-CD1 4.06Å; L410-L456 HydrophobicContact CD1-CD2 3.73Å; L410-L456 HydrophobicContact CD1-CG 3.77Å; L410-L456 HydrophobicContact CD2-CD1 3.9Å; L410-L456 HydrophobicContact CD2-CG 4.2Å
411	S	75	Confident	77.8	Confident	0 Å²	0	15.2 Å²	15.2	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-61.5	-39.5	179.8	78.6	0	0	0	0	113.2	G139 L407 W408 Y409 V415	G139-S411 VanDerWaalsContact CA-O 3.3Å; G139-S411 WeakPolarHBondContact CA-O 3.27Å; G139-S411 VanDerWaalsContact O-CB 3.29Å; G139-S411 WeakPolarHBondContact O-CB 3.49Å; L407-S411 PolarHBondContact O-N 3.48Å; W408-S411 WeakPolarHBondContact O-CB 3.29Å; W408-S411 PolarHBondContact O-N 3.31Å; W408-S411 PolarHBondContact O-OG 3.26Å; Y409-S411 PolarHBondContact O-N 3.01Å; S411-V415 WeakPolarHBondContact O-CG2 3.26Å
412	S	76.9	Confident	79.2	Confident	1 Å²	1	13.6 Å²	13.6	1%	0.007	9%	0.094	C	C	.	.	H	α-helix	trans	-88.5	-16.6	-175.7	-66	0	0	0	0	112.6	Y409 L410 Y416	Y409-S412 PolarHBondContact O-N 2.83Å; L410-S412 VanDerWaalsContact C-N 3.33Å; L410-S412 PolarHBondContact O-N 3.4Å; S412-Y416 WeakPolarHBondContact O-CB 3.29Å; S412-Y416 PolarHBondContact O-N 3.5Å
413	D	83.6	Confident	81	Confident	4 Å²	4	9.2 Å²	9.2	2%	0.021	5%	0.049	C	C	.	.	H	α-helix	trans	-74.8	-54.4	-167.9	178.2	56.2	0	0	0	113.9	L248 Y409 L410 V415 Y416 V417 R448	L248-D413 HydrophobicContact CD1-CB 4.21Å; Y409-D413 HydrophobicContact CE1-CB 4.48Å; Y409-D413 PolarHBondContact O-N 3.46Å; L410-D413 PolarHBondContact O-N 3.27Å; D413-V415 PolarHBondContact O-N 2.92Å; D413-Y416 PolarHBondContact O-N 3Å; D413-V417 WeakPolarHBondContact O-CG2 3.4Å; D413-V417 PolarHBondContact O-N 3.41Å; D413-R448 VanDerWaalsContact CG-NH2 3.26Å; D413-R448 IonicContact OD1-CZ 3.5Å; D413-R448 IonicContact OD1-NE 3.69Å; D413-R448 PolarHBondContact OD1-NE 3.17Å; D413-R448 IonicContact OD1-NH2 3.43Å; D413-R448 PolarHBondContact OD1-NH2 3.3Å; D413-R448 IonicContact OD2-CZ 3.11Å; D413-R448 IonicContact OD2-NE 3.55Å; D413-R448 PolarHBondContact OD2-NE 3.4Å; D413-R448 IonicContact OD2-NH2 3.78Å; D413-R448 PolarHBondContact OD2-NH2 2.97Å
414	L	87.6	Confident	82.5	Confident	26 Å²	26	9 Å²	9	14%	0.136	4%	0.044	C	C	.	.	H	α-helix	trans	-64.1	-34.6	174.6	-67.8	178.8	0	0	0	111.7	P135 M138 I418 L445	P135-L414 HydrophobicContact CB-CB 4.12Å; M138-L414 HydrophobicContact CB-CD1 4.38Å; M138-L414 HydrophobicContact CE-CD1 3.74Å; M138-L414 HydrophobicContact SD-CD1 3.96Å; L414-I418 HydrophobicContact CD2-CD1 4.21Å; L414-I418 VanDerWaalsContact O-CB 3.28Å; L414-I418 WeakPolarHBondContact O-CB 3.28Å; L414-I418 PolarHBondContact O-N 2.66Å; L414-L445 HydrophobicContact CD2-CD1 4.21Å
415	V	92.1	Very high	83.9	Confident	4 Å²	4	8 Å²	8	2%	0.024	4%	0.038	C	C	.	.	I	π-helix	trans	-66	-42.6	178.2	175.9	0	0	0	0	110.7	P255 S411 D413 I419 F420	P255-V415 HydrophobicContact CB-CG1 4.28Å; P255-V415 HydrophobicContact CG-CG1 3.47Å; P255-V415 VanDerWaalsContact CG-CG1 3.47Å; S411-V415 WeakPolarHBondContact O-CG2 3.26Å; D413-V415 PolarHBondContact O-N 2.92Å; V415-I419 HydrophobicContact CG1-CB 4.36Å; V415-I419 WeakPolarHBondContact O-CA 3.47Å; V415-I419 WeakPolarHBondContact O-CB 3.44Å; V415-I419 PolarHBondContact O-N 3.48Å; V415-F420 PolarHBondContact O-N 3.33Å
416	Y	94.1	Very high	85.3	Confident	1 Å²	1	6.6 Å²	6.6	0%	0.004	3%	0.033	C	C	.	.	I	π-helix	trans	-65.8	-47.3	175.1	175.7	-129.2	0	0	0	112.8	F247 L248 L251 S412 D413 F420 P421 K491 S492 M495	F247-Y416 WeakPolarHBondContact CB-OH 3.11Å; L248-Y416 HydrophobicContact CB-CD1 3.73Å; L248-Y416 HydrophobicContact CB-CE1 3.99Å; L248-Y416 HydrophobicContact CB-CG 4.26Å; L248-Y416 HydrophobicContact CD1-CD1 4.12Å; L248-Y416 HydrophobicContact CG-CD1 3.88Å; L248-Y416 HydrophobicContact CG-CG 4.22Å; L251-Y416 HydrophobicContact CB-CD2 3.89Å; L251-Y416 HydrophobicContact CB-CE2 3.58Å; L251-Y416 HydrophobicContact CD1-CE2 4Å; L251-Y416 HydrophobicContact CG-CE2 4.36Å; S412-Y416 WeakPolarHBondContact O-CB 3.29Å; S412-Y416 PolarHBondContact O-N 3.5Å; D413-Y416 PolarHBondContact O-N 3Å; Y416-F420 HydrophobicContact CD2-CD1 4.44Å; Y416-F420 HydrophobicContact CE2-CD1 4.4Å; Y416-F420 WeakPolarHBondContact O-CB 3.41Å; Y416-P421 VanDerWaalsContact O-CD 3.31Å; Y416-P421 WeakPolarHBondContact O-CD 3.05Å; Y416-K491 HydrophobicContact CD1-CB 4.44Å; Y416-K491 HydrophobicContact CE1-CB 4.29Å; Y416-S492 WeakPolarHBondContact OH-CA 3.49Å; Y416-S492 WeakPolarHBondContact OH-CB 3.16Å; Y416-S492 PolarHBondContact OH-OG 2.94Å; Y416-M495 HydrophobicContact CD2-CG 4.08Å; Y416-M495 HydrophobicContact CE1-CB 4.14Å; Y416-M495 HydrophobicContact CE1-CG 4.48Å; Y416-M495 HydrophobicContact CE2-CB 4.22Å; Y416-M495 HydrophobicContact CE2-CE 3.85Å; Y416-M495 HydrophobicContact CE2-CG 3.68Å; Y416-M495 HydrophobicContact CE2-SD 4.47Å; Y416-M495 VanDerWaalsContact O-CG 3.28Å; Y416-M495 WeakPolarHBondContact O-CG 3.09Å; Y416-M495 WeakPolarHBondContact OH-CE 3.32Å
417	V	93.7	Very high	86.3	Confident	0 Å²	0	6.5 Å²	6.5	0%	0	3%	0.032	C	C	.	.	I	π-helix	trans	-76.9	-34.4	-174	176.3	0	0	0	0	112.7	D413 P421 G444 R448 K491 S498	D413-V417 WeakPolarHBondContact O-CG2 3.4Å; D413-V417 PolarHBondContact O-N 3.41Å; V417-P421 WeakPolarHBondContact O-CG 3.43Å; V417-G444 WeakPolarHBondContact CG1-O 3.45Å; V417-R448 HydrophobicContact CG1-CB 4.14Å; V417-R448 HydrophobicContact CG2-CB 4.49Å; V417-R448 HydrophobicContact CG2-CG 4.34Å; V417-K491 HydrophobicContact CG2-CB 4.49Å; V417-S498 WeakPolarHBondContact O-CB 3.43Å; V417-S498 PolarHBondContact O-OG 3.47Å
418	I	93.8	Very high	87.3	Confident	1 Å²	1	9.5 Å²	9.5	1%	0.005	5%	0.045	C	C	.	.	I	π-helix	trans	-104.6	-53.1	-172.4	-55.8	176.6	0	0	0	111.3	L132 P135 L414 Q422 Y441 L445	L132-I418 HydrophobicContact CD2-CG2 4.17Å; P135-I418 HydrophobicContact CB-CD1 4.29Å; P135-I418 HydrophobicContact CG-CG2 4.16Å; L414-I418 HydrophobicContact CD2-CD1 4.21Å; L414-I418 VanDerWaalsContact O-CB 3.28Å; L414-I418 WeakPolarHBondContact O-CB 3.28Å; L414-I418 PolarHBondContact O-N 2.66Å; I418-Q422 WeakPolarHBondContact O-CG 3.41Å; I418-Y441 HydrophobicContact CD1-CE2 4.43Å; I418-Y441 HydrophobicContact CG2-CD2 3.51Å; I418-Y441 HydrophobicContact CG2-CE2 3.9Å; I418-Y441 HydrophobicContact CG2-CG 4.25Å; I418-L445 HydrophobicContact CD1-CB 4.29Å; I418-L445 HydrophobicContact CD1-CD1 3.99Å
419	I	95.2	Very high	88.3	Confident	1 Å²	1	9.9 Å²	9.9	1%	0.005	5%	0.049	C	C	.	.	I	π-helix	trans	-79.2	-41.2	-170.1	-53.6	-55.6	0	0	0	112.1	M116 F120 L132 P135 P255 V415 Q422 L423	M116-I419 HydrophobicContact CE-CG2 4.31Å; F120-I419 HydrophobicContact CE2-CG2 3.96Å; F120-I419 HydrophobicContact CZ-CG2 3.99Å; L132-I419 HydrophobicContact CB-CD1 4.18Å; L132-I419 HydrophobicContact CD2-CD1 3.96Å; L132-I419 WeakPolarHBondContact O-CD1 3.19Å; P135-I419 HydrophobicContact CB-CD1 4.35Å; P135-I419 HydrophobicContact CB-CG1 4.49Å; P135-I419 HydrophobicContact CG-CD1 3.61Å; P135-I419 HydrophobicContact CG-CG1 4.27Å; P255-I419 HydrophobicContact CB-CB 4.19Å; P255-I419 HydrophobicContact CB-CG2 3.61Å; P255-I419 HydrophobicContact CG-CB 4.47Å; P255-I419 HydrophobicContact CG-CG2 4.39Å; V415-I419 HydrophobicContact CG1-CB 4.36Å; V415-I419 WeakPolarHBondContact O-CA 3.47Å; V415-I419 WeakPolarHBondContact O-CB 3.44Å; V415-I419 PolarHBondContact O-N 3.48Å; I419-Q422 WeakPolarHBondContact O-CB 3.33Å; I419-Q422 PolarHBondContact O-N 3.37Å; I419-Q422 VanDerWaalsContact O-N 3.14Å; I419-L423 PolarHBondContact O-N 2.91Å
420	F	95.8	Very high	89	Confident	9 Å²	9	13.4 Å²	13.4	4%	0.039	7%	0.065	C	C	.	.	H	α-helix	trans	-59.3	-47.6	-177.7	179.4	-109.9	0	0	0	113.3	F104 L251 I254 P255 V415 Y416 Q422 L423 L424 M495	F104-F420 AromaticContact CZ-CE2 4Å; F104-F420 HydrophobicContact CZ-CE2 4Å; L251-F420 HydrophobicContact CB-CD1 4.02Å; L251-F420 HydrophobicContact CB-CE1 3.78Å; L251-F420 HydrophobicContact CB-CE2 4.32Å; L251-F420 HydrophobicContact CB-CG 4.4Å; L251-F420 HydrophobicContact CB-CZ 3.93Å; L251-F420 HydrophobicContact CD1-CE1 3.85Å; L251-F420 HydrophobicContact CD1-CZ 4.3Å; L251-F420 HydrophobicContact CD2-CE1 4.18Å; L251-F420 HydrophobicContact CD2-CE2 4.47Å; L251-F420 HydrophobicContact CD2-CZ 3.77Å; L251-F420 HydrophobicContact CG-CE1 4.14Å; L251-F420 HydrophobicContact CG-CZ 4.21Å; L251-F420 WeakPolarHBondContact O-CD2 3.27Å; I254-F420 HydrophobicContact CB-CD2 4.38Å; I254-F420 HydrophobicContact CB-CE2 4.3Å; I254-F420 HydrophobicContact CD1-CE2 3.88Å; P255-F420 HydrophobicContact CG-CB 3.97Å; P255-F420 HydrophobicContact CG-CD2 4.48Å; V415-F420 PolarHBondContact O-N 3.33Å; Y416-F420 HydrophobicContact CD2-CD1 4.44Å; Y416-F420 HydrophobicContact CE2-CD1 4.4Å; Y416-F420 WeakPolarHBondContact O-CB 3.41Å; F420-Q422 VanDerWaalsContact C-N 3.27Å; F420-Q422 PolarHBondContact O-N 3.37Å; F420-L423 WeakPolarHBondContact O-CB 3.48Å; F420-L423 PolarHBondContact O-N 3.07Å; F420-L423 VanDerWaalsContact O-N 3.16Å; F420-L424 HydrophobicContact CD1-CD1 4.07Å; F420-L424 HydrophobicContact CE1-CD1 3.47Å; F420-L424 VanDerWaalsContact CE1-CD1 3.47Å; F420-L424 HydrophobicContact CE1-CG 4.1Å; F420-L424 HydrophobicContact CE2-CD1 4.41Å; F420-L424 HydrophobicContact CE2-CD2 4.3Å; F420-L424 HydrophobicContact CE2-CG 4.15Å; F420-L424 HydrophobicContact CZ-CD1 3.67Å; F420-L424 HydrophobicContact CZ-CD2 4.02Å; F420-L424 HydrophobicContact CZ-CG 3.88Å; F420-L424 PolarHBondContact O-N 3.42Å; F420-M495 HydrophobicContact CD1-CG 4.23Å; F420-M495 HydrophobicContact CD1-SD 3.97Å; F420-M495 HydrophobicContact CE1-SD 4.3Å
421	P	95.6	Very high	89.3	Confident	0 Å²	0	13 Å²	13	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-56.3	-39.1	173	-32.5	40.3	0	0	0	114.2	Y416 V417 L424 S425 M495 F499	Y416-P421 VanDerWaalsContact O-CD 3.31Å; Y416-P421 WeakPolarHBondContact O-CD 3.05Å; V417-P421 WeakPolarHBondContact O-CG 3.43Å; P421-L424 PolarHBondContact O-N 3.33Å; P421-S425 WeakPolarHBondContact O-CB 3.29Å; P421-S425 PolarHBondContact O-N 2.89Å; P421-S425 PolarHBondContact O-OG 2.94Å; P421-M495 HydrophobicContact CG-CB 4.49Å; P421-M495 HydrophobicContact CG-CG 3.64Å; P421-M495 WeakPolarHBondContact CG-O 3.41Å; P421-M495 HydrophobicContact CG-SD 3.95Å; P421-F499 HydrophobicContact CB-CB 3.87Å; P421-F499 HydrophobicContact CB-CD2 4.48Å; P421-F499 HydrophobicContact CG-CB 4.43Å
422	Q	94.9	Very high	89.9	Confident	0 Å²	0	13 Å²	13	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-67.4	-42.7	179.4	-61.3	-79.1	-2.6	0	0	109.9	F120 Y124 L132 I418 I419 F420 L424 S425 V426 S437 N502	F120-Q422 HydrophobicContact CD1-CB 4.34Å; F120-Q422 HydrophobicContact CE1-CB 3.8Å; F120-Q422 HydrophobicContact CZ-CB 4.3Å; Y124-Q422 PolarHBondContact OH-OE1 3.49Å; L132-Q422 HydrophobicContact CD1-CG 4.5Å; L132-Q422 HydrophobicContact CD2-CG 3.95Å; I418-Q422 WeakPolarHBondContact O-CG 3.41Å; I419-Q422 WeakPolarHBondContact O-CB 3.33Å; I419-Q422 PolarHBondContact O-N 3.37Å; I419-Q422 VanDerWaalsContact O-N 3.14Å; F420-Q422 VanDerWaalsContact C-N 3.27Å; F420-Q422 PolarHBondContact O-N 3.37Å; Q422-L424 PolarHBondContact O-N 2.96Å; Q422-S425 WeakPolarHBondContact O-CB 3.47Å; Q422-S425 PolarHBondContact O-N 3.45Å; Q422-V426 VanDerWaalsContact O-CG2 3.32Å; Q422-V426 WeakPolarHBondContact O-CG2 3.31Å; Q422-V426 PolarHBondContact O-N 3.33Å; Q422-S437 VanDerWaalsContact CD-OG 3.24Å; Q422-S437 PolarHBondContact NE2-O 3.16Å; Q422-S437 PolarHBondContact NE2-OG 3.44Å; Q422-S437 PolarHBondContact OE1-OG 3.22Å; Q422-N502 PolarHBondContact OE1-ND2 3.08Å
423	L	94.6	Very high	90.6	Very high	0 Å²	0	13 Å²	13	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-59.4	-47.1	176.3	-177	61.5	0	0	0	111.6	F104 M116 F120 I254 P255 F260 I419 F420 S425 V426 L427	F104-L423 HydrophobicContact CD1-CD1 4.42Å; F104-L423 HydrophobicContact CD1-CD2 3.38Å; F104-L423 HydrophobicContact CD1-CG 3.79Å; F104-L423 HydrophobicContact CE1-CD2 3.37Å; F104-L423 HydrophobicContact CE1-CG 3.66Å; F104-L423 HydrophobicContact CG-CD2 4.35Å; F104-L423 HydrophobicContact CZ-CD2 4.34Å; M116-L423 HydrophobicContact CE-CB 3.93Å; M116-L423 HydrophobicContact CE-CD1 3.27Å; M116-L423 HydrophobicContact CE-CD2 3.53Å; M116-L423 HydrophobicContact CE-CG 3.69Å; M116-L423 HydrophobicContact SD-CD1 3.87Å; F120-L423 HydrophobicContact CE1-CB 4.3Å; F120-L423 HydrophobicContact CE1-CD1 4.49Å; F120-L423 HydrophobicContact CZ-CB 3.99Å; F120-L423 HydrophobicContact CZ-CD1 4.19Å; I254-L423 HydrophobicContact CG2-CD2 4Å; P255-L423 HydrophobicContact CB-CD2 4.17Å; F260-L423 HydrophobicContact CE2-CD2 4.26Å; F260-L423 HydrophobicContact CZ-CD2 4.32Å; I419-L423 PolarHBondContact O-N 2.91Å; F420-L423 WeakPolarHBondContact O-CB 3.48Å; F420-L423 PolarHBondContact O-N 3.07Å; F420-L423 VanDerWaalsContact O-N 3.16Å; L423-S425 VanDerWaalsContact C-N 3.28Å; L423-S425 PolarHBondContact O-N 3.27Å; L423-V426 PolarHBondContact O-N 2.93Å; L423-L427 HydrophobicContact CD1-CD1 3.51Å; L423-L427 HydrophobicContact CD1-CG 4.05Å; L423-L427 HydrophobicContact CG-CD1 4.06Å; L423-L427 PolarHBondContact O-N 3.41Å; L423-L427 VanDerWaalsContact O-N 3.16Å
424	L	94.3	Very high	90.9	Very high	40 Å²	40	13.5 Å²	13.5	21%	0.209	7%	0.066	C	C	.	.	H	α-helix	trans	-57.3	-45.7	175.9	-73.9	176.5	0	0	0	111.3	F104 F420 P421 Q422 F428 F499	F104-L424 HydrophobicContact CE1-CD2 4.14Å; F104-L424 HydrophobicContact CZ-CD2 3.69Å; F420-L424 HydrophobicContact CD1-CD1 4.07Å; F420-L424 HydrophobicContact CE1-CD1 3.47Å; F420-L424 VanDerWaalsContact CE1-CD1 3.47Å; F420-L424 HydrophobicContact CE1-CG 4.1Å; F420-L424 HydrophobicContact CE2-CD1 4.41Å; F420-L424 HydrophobicContact CE2-CD2 4.3Å; F420-L424 HydrophobicContact CE2-CG 4.15Å; F420-L424 HydrophobicContact CZ-CD1 3.67Å; F420-L424 HydrophobicContact CZ-CD2 4.02Å; F420-L424 HydrophobicContact CZ-CG 3.88Å; F420-L424 PolarHBondContact O-N 3.42Å; P421-L424 PolarHBondContact O-N 3.33Å; Q422-L424 PolarHBondContact O-N 2.96Å; L424-F428 HydrophobicContact CD2-CD2 4.09Å; L424-F428 HydrophobicContact CD2-CE2 4.3Å; L424-F428 WeakPolarHBondContact O-CB 3.36Å; L424-F428 PolarHBondContact O-N 3.39Å; L424-F499 HydrophobicContact CB-CD2 4.14Å; L424-F499 HydrophobicContact CB-CE2 3.87Å; L424-F499 HydrophobicContact CD1-CD2 4.38Å; L424-F499 HydrophobicContact CD1-CE2 4.49Å
425	S	92.6	Very high	91	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-63.2	-50.4	-178.4	-59.4	0	0	0	0	111.6	Y124 P421 Q422 L423 L427 V429 N502	Y124-S425 WeakPolarHBondContact OH-CB 3.31Å; P421-S425 WeakPolarHBondContact O-CB 3.29Å; P421-S425 PolarHBondContact O-N 2.89Å; P421-S425 PolarHBondContact O-OG 2.94Å; Q422-S425 WeakPolarHBondContact O-CB 3.47Å; Q422-S425 PolarHBondContact O-N 3.45Å; L423-S425 VanDerWaalsContact C-N 3.28Å; L423-S425 PolarHBondContact O-N 3.27Å; S425-L427 VanDerWaalsContact C-N 3.35Å; S425-L427 PolarHBondContact O-N 3.41Å; S425-V429 WeakPolarHBondContact O-CB 3.35Å; S425-V429 PolarHBondContact O-N 3.4Å; S425-N502 WeakPolarHBondContact CB-ND2 3.25Å; S425-N502 PolarHBondContact OG-ND2 2.9Å
426	V	90.5	Very high	91.1	Very high	1 Å²	1	13.6 Å²	13.6	1%	0.006	6%	0.064	C	C	.	.	H	α-helix	trans	-65.7	-35.5	-176.3	174.4	0	0	0	0	113.1	P119 F120 L123 Y124 Q422 L423	P119-V426 HydrophobicContact CB-CG1 3.72Å; P119-V426 WeakPolarHBondContact O-CG1 3.44Å; F120-V426 HydrophobicContact CD1-CB 4.3Å; F120-V426 HydrophobicContact CD1-CG2 3.59Å; F120-V426 HydrophobicContact CE1-CB 4.39Å; F120-V426 HydrophobicContact CE1-CG2 3.97Å; L123-V426 HydrophobicContact CB-CG1 4.14Å; L123-V426 HydrophobicContact CD2-CB 4.07Å; L123-V426 HydrophobicContact CD2-CG1 3.87Å; L123-V426 HydrophobicContact CD2-CG2 3.87Å; Y124-V426 HydrophobicContact CD2-CG2 4.08Å; Y124-V426 HydrophobicContact CE1-CG2 4.11Å; Y124-V426 HydrophobicContact CE2-CG2 3.24Å; Y124-V426 VanDerWaalsContact OH-CG2 3.24Å; Y124-V426 WeakPolarHBondContact OH-CG2 3.43Å; Q422-V426 VanDerWaalsContact O-CG2 3.32Å; Q422-V426 WeakPolarHBondContact O-CG2 3.31Å; Q422-V426 PolarHBondContact O-N 3.33Å; L423-V426 PolarHBondContact O-N 2.93Å
427	L	88.3	Confident	91.1	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-89.2	-37.4	-176.1	-64.9	179.7	0	0	0	113	F104 M108 P119 L423 S425 L542	F104-L427 HydrophobicContact CD1-CD1 3.72Å; F104-L427 HydrophobicContact CE1-CD1 4.34Å; M108-L427 HydrophobicContact CG-CD1 4.32Å; M108-L427 HydrophobicContact SD-CD1 4.13Å; M108-L427 HydrophobicContact SD-CD2 4.23Å; P119-L427 HydrophobicContact CB-CD2 4.47Å; L423-L427 HydrophobicContact CD1-CD1 3.51Å; L423-L427 HydrophobicContact CD1-CG 4.05Å; L423-L427 HydrophobicContact CG-CD1 4.06Å; L423-L427 PolarHBondContact O-N 3.41Å; L423-L427 VanDerWaalsContact O-N 3.16Å; S425-L427 VanDerWaalsContact C-N 3.35Å; S425-L427 PolarHBondContact O-N 3.41Å; L427-L542 HydrophobicContact CB-CD1 4.07Å; L427-L542 WeakPolarHBondContact O-CD1 3.36Å; L427-L542 WeakPolarHBondContact O-CG 3.26Å; L427-L542 PolarHBondContact O-N 3.06Å
428	F	89	Confident	91.2	Very high	68 Å²	68	15.2 Å²	15.2	30%	0.298	7%	0.074	S	C	.	.	H	α-helix	trans	-117.8	-13.4	-166.6	-54.5	-70	0	0	0	115.2	F103 F104 L424 T541 L542	F103-F428 HydrophobicContact CB-CZ 4.11Å; F103-F428 WeakPolarHBondContact O-CZ 3.38Å; F104-F428 AromaticContact CD1-CE2 3.96Å; F104-F428 HydrophobicContact CD1-CE2 3.96Å; F104-F428 HydrophobicContact CD1-CZ 4.33Å; F104-F428 HydrophobicContact CE1-CD2 4.46Å; F104-F428 AromaticContact CE1-CE2 3.5Å; F104-F428 HydrophobicContact CE1-CE2 3.5Å; F104-F428 HydrophobicContact CE1-CZ 4.27Å; F104-F428 AromaticContact CZ-CE2 3.83Å; F104-F428 HydrophobicContact CZ-CE2 3.83Å; L424-F428 HydrophobicContact CD2-CD2 4.09Å; L424-F428 HydrophobicContact CD2-CE2 4.3Å; L424-F428 WeakPolarHBondContact O-CB 3.36Å; L424-F428 PolarHBondContact O-N 3.39Å; F428-T541 VanDerWaalsContact O-CG2 3.3Å; F428-T541 WeakPolarHBondContact O-CG2 3.36Å; F428-L542 HydrophobicContact CD1-CD1 3.89Å; F428-L542 HydrophobicContact CE1-CD1 3.57Å; F428-L542 HydrophobicContact CZ-CD1 4.29Å
429	V	87.7	Confident	91.2	Very high	26 Å²	26	15.7 Å²	15.7	16%	0.158	8%	0.078	C	C	.	.			trans	-107.6	131.1	179.5	-172.7	0	0	0	0	110.9	S425 T432 F499 V503 Y507 T541	S425-V429 WeakPolarHBondContact O-CB 3.35Å; S425-V429 PolarHBondContact O-N 3.4Å; V429-T432 HydrophobicContact CB-CG2 3.78Å; V429-T432 HydrophobicContact CG1-CG2 3.69Å; V429-F499 HydrophobicContact CG2-CE2 4.06Å; V429-F499 HydrophobicContact CG2-CZ 3.97Å; V429-V503 HydrophobicContact CG1-CG2 4.18Å; V429-V503 HydrophobicContact CG2-CG2 4.46Å; V429-Y507 HydrophobicContact CG1-CE2 4.33Å; V429-T541 VanDerWaalsContact C-CG2 3.41Å; V429-T541 PolarHBondContact O-OG1 2.84Å
430	K	81.4	Confident	91.2	Very high	88 Å²	88	15.6 Å²	15.6	38%	0.383	8%	0.078	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79.3	148.2	174.7	-75.3	-175.5	-179.8	-170.5	0	110.9	T432 Y507 T541 V543	K430-T432 VanDerWaalsContact C-N 3.27Å; K430-T432 PolarHBondContact O-N 3.1Å; K430-Y507 VanDerWaalsContact O-CZ 3.24Å; K430-Y507 PolarHBondContact O-OH 2.85Å; K430-T541 VanDerWaalsContact CA-OG1 3.24Å; K430-T541 WeakPolarHBondContact CA-OG1 3.46Å; K430-T541 HydrophobicContact CG-CG2 3.7Å; K430-T541 WeakPolarHBondContact CG-OG1 3.45Å; K430-V543 WeakPolarHBondContact CE-O 2.97Å; K430-V543 PolarHBondContact NZ-O 2.92Å
431	G	79.1	Confident	91.2	Very high	2 Å²	2	16.6 Å²	16.6	2%	0.021	8%	0.082	C	C	.	.	T	Hydrogen-bonded Turn	trans	71.9	14.3	171.7	0	0	0	0	0	115.5
432	T	87.8	Confident	91.1	Very high	1 Å²	1	20.5 Å²	20.5	1%	0.006	10%	0.102	C	C	.	.			trans	-73.7	141.5	171	53.5	0	0	0	0	110.5	L123 V429 K430	L123-T432 WeakPolarHBondContact CD2-OG1 3.26Å; V429-T432 HydrophobicContact CB-CG2 3.78Å; V429-T432 HydrophobicContact CG1-CG2 3.69Å; K430-T432 VanDerWaalsContact C-N 3.27Å; K430-T432 PolarHBondContact O-N 3.1Å
433	N	90.1	Very high	91.1	Very high	2 Å²	2	25 Å²	25	1%	0.011	12%	0.121	C	C	.	.			trans	-141.2	174.4	-171.9	66.7	29.5	0	0	0	111.7	Y435 G436 S437 S506 T509 A527 M537	N433-Y435 VanDerWaalsContact C-N 3.31Å; N433-Y435 PolarHBondContact O-N 2.93Å; N433-Y435 PolarHBondContact OD1-N 3.14Å; N433-G436 PolarHBondContact O-N 3.49Å; N433-G436 PolarHBondContact OD1-N 2.98Å; N433-S437 PolarHBondContact O-N 3.11Å; N433-S506 PolarHBondContact N-OG 3.2Å; N433-S506 PolarHBondContact ND2-O 2.93Å; N433-S506 VanDerWaalsContact ND2-O 3.11Å; N433-S506 PolarHBondContact O-OG 3.37Å; N433-S506 WeakPolarHBondContact OD1-CA 3.34Å; N433-S506 PolarHBondContact OD1-OG 2.92Å; N433-T509 PolarHBondContact ND2-OG1 3.31Å; N433-T509 PolarHBondContact OD1-OG1 3.46Å; N433-A527 HydrophobicContact CB-CB 4.43Å; N433-M537 HydrophobicContact CB-SD 3.91Å
434	T	90.6	Very high	91	Very high	13 Å²	13	25 Å²	25	8%	0.08	12%	0.121	C	C	.	.	H	α-helix	trans	-60.8	-35.8	-175.7	-45.8	0	0	0	0	113.4	Y124 M128 S437 V438 M525	Y124-T434 WeakPolarHBondContact CA-OG1 3.45Å; Y124-T434 VanDerWaalsContact O-CG2 3.28Å; Y124-T434 WeakPolarHBondContact O-CG2 3.28Å; Y124-T434 PolarHBondContact O-OG1 3.18Å; M128-T434 HydrophobicContact CB-CG2 3.79Å; M128-T434 HydrophobicContact CG-CG2 4.2Å; T434-S437 WeakPolarHBondContact O-CB 3.45Å; T434-S437 PolarHBondContact O-N 2.92Å; T434-V438 WeakPolarHBondContact O-CG2 3.29Å; T434-V438 PolarHBondContact O-N 3.08Å; T434-M525 HydrophobicContact CG2-CB 4.48Å; T434-M525 HydrophobicContact CG2-SD 3.51Å; T434-M525 VanDerWaalsContact CG2-SD 3.51Å
435	Y	90.6	Very high	90.8	Very high	32 Å²	32	25.5 Å²	25.5	13%	0.125	12%	0.124	C	C	.	.	H	α-helix	trans	-65.6	-43.3	178.9	-68.5	-65.6	0	0	0	112.6	N433 S437 V438 A439 T509 F513 Y522 D523 F524 M525 A527 V528	N433-Y435 VanDerWaalsContact C-N 3.31Å; N433-Y435 PolarHBondContact O-N 2.93Å; N433-Y435 PolarHBondContact OD1-N 3.14Å; Y435-S437 VanDerWaalsContact C-N 3.31Å; Y435-V438 PolarHBondContact O-N 3.33Å; Y435-A439 PolarHBondContact O-N 3.18Å; Y435-T509 HydrophobicContact CD2-CG2 4.17Å; Y435-T509 HydrophobicContact CG-CG2 4.05Å; Y435-F513 HydrophobicContact CD2-CE2 4.48Å; Y435-F513 AromaticContact CE2-CE2 3.93Å; Y435-F513 HydrophobicContact CE2-CE2 3.93Å; Y435-F513 HydrophobicContact CE2-CZ 4.45Å; Y435-Y522 PolarHBondContact OH-O 3.29Å; Y435-D523 WeakPolarHBondContact CE2-OD1 2.94Å; Y435-D523 WeakPolarHBondContact OH-CA 3.41Å; Y435-D523 PolarHBondContact OH-OD1 2.71Å; Y435-F524 HydrophobicContact CE1-CD1 4.25Å; Y435-F524 AromaticContact CE1-CE1 3.56Å; Y435-F524 HydrophobicContact CE1-CE1 3.56Å; Y435-F524 HydrophobicContact CE1-CE2 4.47Å; Y435-F524 AromaticContact CE1-CZ 3.69Å; Y435-F524 HydrophobicContact CE1-CZ 3.69Å; Y435-F524 WeakPolarHBondContact OH-CD1 3.46Å; Y435-F524 PolarHBondContact OH-N 2.91Å; Y435-M525 HydrophobicContact CD1-SD 4.46Å; Y435-M525 HydrophobicContact CE1-CB 4.2Å; Y435-M525 HydrophobicContact CE1-CG 3.84Å; Y435-M525 HydrophobicContact CE1-SD 4.28Å; Y435-M525 HydrophobicContact CE2-CB 4.35Å; Y435-M525 PolarHBondContact OH-N 2.65Å; Y435-A527 HydrophobicContact CD2-CB 3.83Å; Y435-A527 HydrophobicContact CE2-CB 3.77Å; Y435-V528 HydrophobicContact CD2-CG2 4.41Å
436	G	93.1	Very high	90.8	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-61.6	-42.6	172.1	0	0	0	0	0	111.5	N433 V438 A439 A440 N502 S506	N433-G436 PolarHBondContact O-N 3.49Å; N433-G436 PolarHBondContact OD1-N 2.98Å; G436-V438 VanDerWaalsContact C-N 3.34Å; G436-V438 PolarHBondContact O-N 3.05Å; G436-A439 PolarHBondContact O-N 3.46Å; G436-A440 WeakPolarHBondContact O-CB 3.49Å; G436-A440 PolarHBondContact O-N 2.94Å; G436-N502 WeakPolarHBondContact CA-O 3.37Å; G436-N502 WeakPolarHBondContact CA-OD1 3.34Å; G436-N502 WeakPolarHBondContact O-CA 3.15Å; G436-N502 PolarHBondContact O-OD1 3.27Å; G436-S506 WeakPolarHBondContact CA-OG 3.12Å
437	S	94.6	Very high	90.9	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-60.1	-42.2	178.5	-168.1	0	0	0	0	112.5	Y124 M128 Q422 N433 T434 Y435 Y441 N502	Y124-S437 VanDerWaalsContact CD2-OG 3.28Å; Y124-S437 WeakPolarHBondContact CD2-OG 3.45Å; Y124-S437 VanDerWaalsContact CE2-OG 3.29Å; Y124-S437 WeakPolarHBondContact CE2-OG 3.3Å; M128-S437 WeakPolarHBondContact CE-OG 3.39Å; M128-S437 WeakPolarHBondContact CG-OG 3.43Å; Q422-S437 VanDerWaalsContact CD-OG 3.24Å; Q422-S437 PolarHBondContact NE2-O 3.16Å; Q422-S437 PolarHBondContact NE2-OG 3.44Å; Q422-S437 PolarHBondContact OE1-OG 3.22Å; N433-S437 PolarHBondContact O-N 3.11Å; T434-S437 WeakPolarHBondContact O-CB 3.45Å; T434-S437 PolarHBondContact O-N 2.92Å; Y435-S437 VanDerWaalsContact C-N 3.31Å; S437-Y441 WeakPolarHBondContact O-CB 3.17Å; S437-Y441 PolarHBondContact O-N 2.89Å; S437-N502 PolarHBondContact N-OD1 3.14Å; S437-N502 VanDerWaalsContact N-OD1 3.08Å
438	V	94.8	Very high	91	Very high	35 Å²	35	32.9 Å²	32.9	21%	0.212	16%	0.162	C	C	.	.	H	α-helix	trans	-65.6	-44.7	174.8	172.7	0	0	0	0	111.5	M128 T434 Y435 G436 A440 Y441 I442 M525	M128-V438 HydrophobicContact CE-CG2 4.46Å; M128-V438 HydrophobicContact SD-CG2 3.49Å; M128-V438 WeakPolarHBondContact SD-CG2 3.43Å; T434-V438 WeakPolarHBondContact O-CG2 3.29Å; T434-V438 PolarHBondContact O-N 3.08Å; Y435-V438 PolarHBondContact O-N 3.33Å; G436-V438 VanDerWaalsContact C-N 3.34Å; G436-V438 PolarHBondContact O-N 3.05Å; V438-A440 PolarHBondContact O-N 3.22Å; V438-Y441 WeakPolarHBondContact O-CB 3.1Å; V438-Y441 PolarHBondContact O-N 2.98Å; V438-I442 HydrophobicContact CG1-CD1 3.84Å; V438-I442 WeakPolarHBondContact O-CG1 3.19Å; V438-I442 PolarHBondContact O-N 3.18Å; V438-M525 HydrophobicContact CG2-CE 4.11Å; V438-M525 HydrophobicContact CG2-SD 4.33Å
439	A	94.9	Very high	90.9	Very high	11 Å²	11	33.5 Å²	33.5	9%	0.091	17%	0.168	C	C	.	.	H	α-helix	trans	-59.4	-48.6	177.2	0	0	0	0	0	110.8	Y435 G436 Y441 I442 F443 F505	Y435-A439 PolarHBondContact O-N 3.18Å; G436-A439 PolarHBondContact O-N 3.46Å; A439-Y441 VanDerWaalsContact C-N 3.33Å; A439-Y441 PolarHBondContact O-N 3.45Å; A439-I442 PolarHBondContact O-N 3.38Å; A439-I442 VanDerWaalsContact O-N 3.15Å; A439-F443 VanDerWaalsContact O-CD2 3.3Å; A439-F443 WeakPolarHBondContact O-CD2 3.47Å; A439-F443 PolarHBondContact O-N 3.32Å; A439-F505 HydrophobicContact CB-CB 3.85Å; A439-F505 HydrophobicContact CB-CD1 4.17Å; A439-F505 HydrophobicContact CB-CD2 3.74Å; A439-F505 HydrophobicContact CB-CE2 4.31Å; A439-F505 HydrophobicContact CB-CG 3.65Å
440	A	95.9	Very high	90.8	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-56.5	-44.5	176	0	0	0	0	0	113	G436 V438 I442 G444 S498 N502	G436-A440 WeakPolarHBondContact O-CB 3.49Å; G436-A440 PolarHBondContact O-N 2.94Å; V438-A440 PolarHBondContact O-N 3.22Å; A440-I442 PolarHBondContact O-N 3.48Å; A440-G444 PolarHBondContact O-N 3.47Å; A440-S498 WeakPolarHBondContact CB-O 3.27Å; A440-S498 PolarHBondContact O-OG 3.03Å; A440-N502 HydrophobicContact CB-CB 3.69Å
441	Y	94.9	Very high	90.9	Very high	30 Å²	30	28.2 Å²	28.2	12%	0.118	14%	0.144	C	C	.	.	H	α-helix	trans	-57.6	-48.4	174.9	-171.5	-77.8	0	0	0	111.7	M128 L131 L132 P135 I418 S437 V438 A439 L445	M128-Y441 HydrophobicContact CE-CD2 4.22Å; M128-Y441 HydrophobicContact CE-CG 4.45Å; L131-Y441 HydrophobicContact CD1-CE1 4.39Å; L131-Y441 HydrophobicContact CD1-CE2 4.32Å; L131-Y441 HydrophobicContact CD2-CD1 4.39Å; L131-Y441 HydrophobicContact CD2-CD2 4.3Å; L131-Y441 HydrophobicContact CD2-CE2 4.44Å; L131-Y441 HydrophobicContact CD2-CG 4.28Å; L131-Y441 HydrophobicContact CG-CD2 4.17Å; L131-Y441 HydrophobicContact CG-CE2 3.9Å; L132-Y441 HydrophobicContact CD2-CD2 4.02Å; P135-Y441 HydrophobicContact CG-CE2 3.98Å; I418-Y441 HydrophobicContact CD1-CE2 4.43Å; I418-Y441 HydrophobicContact CG2-CD2 3.51Å; I418-Y441 HydrophobicContact CG2-CE2 3.9Å; I418-Y441 HydrophobicContact CG2-CG 4.25Å; S437-Y441 WeakPolarHBondContact O-CB 3.17Å; S437-Y441 PolarHBondContact O-N 2.89Å; V438-Y441 WeakPolarHBondContact O-CB 3.1Å; V438-Y441 PolarHBondContact O-N 2.98Å; A439-Y441 VanDerWaalsContact C-N 3.33Å; A439-Y441 PolarHBondContact O-N 3.45Å; Y441-L445 HydrophobicContact CE1-CD2 3.94Å; Y441-L445 WeakPolarHBondContact O-CB 3.33Å; Y441-L445 PolarHBondContact O-N 2.87Å
442	I	94.4	Very high	91	Very high	82 Å²	82	28.3 Å²	28.3	42%	0.421	15%	0.145	S	C	.	.	H	α-helix	trans	-65.8	-49.1	-178.7	-67.2	168.7	0	0	0	110.9	V438 A439 A440 L445 L446	V438-I442 HydrophobicContact CG1-CD1 3.84Å; V438-I442 WeakPolarHBondContact O-CG1 3.19Å; V438-I442 PolarHBondContact O-N 3.18Å; A439-I442 PolarHBondContact O-N 3.38Å; A439-I442 VanDerWaalsContact O-N 3.15Å; A440-I442 PolarHBondContact O-N 3.48Å; I442-L445 PolarHBondContact O-N 3.06Å; I442-L446 HydrophobicContact CG2-CD1 3.58Å; I442-L446 HydrophobicContact CG2-CG 4.19Å; I442-L446 VanDerWaalsContact O-CB 3.28Å; I442-L446 WeakPolarHBondContact O-CB 3.48Å; I442-L446 VanDerWaalsContact O-CG 3.23Å; I442-L446 WeakPolarHBondContact O-CG 3.38Å; I442-L446 PolarHBondContact O-N 3.37Å
443	F	93.1	Very high	90.5	Very high	94 Å²	94	28.7 Å²	28.7	41%	0.412	15%	0.146	S	C	.	.	H	α-helix	trans	-62.6	-46.5	179.9	-88.4	-93.2	0	0	0	111.7	A439 L447 A501 F505	A439-F443 VanDerWaalsContact O-CD2 3.3Å; A439-F443 WeakPolarHBondContact O-CD2 3.47Å; A439-F443 PolarHBondContact O-N 3.32Å; F443-L447 WeakPolarHBondContact O-CB 3.34Å; F443-L447 VanDerWaalsContact O-CG 3.3Å; F443-L447 WeakPolarHBondContact O-CG 3.23Å; F443-L447 PolarHBondContact O-N 3.09Å; F443-A501 HydrophobicContact CB-CB 4.12Å; F443-A501 HydrophobicContact CD2-CB 4.03Å; F443-A501 HydrophobicContact CG-CB 4.09Å; F443-F505 AromaticContact CE2-CE2 3.98Å; F443-F505 HydrophobicContact CE2-CE2 3.98Å; F443-F505 HydrophobicContact CE2-CZ 4.26Å; F443-F505 HydrophobicContact CZ-CE2 4.44Å
444	G	93	Very high	89.6	Confident	0 Å²	0	31 Å²	31	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-59.9	-48.4	177.2	0	0	0	0	0	112	V417 A440 R448	V417-G444 WeakPolarHBondContact CG1-O 3.45Å; A440-G444 PolarHBondContact O-N 3.47Å; G444-R448 WeakPolarHBondContact O-CB 3.46Å; G444-R448 PolarHBondContact O-N 3.42Å
445	L	91.4	Very high	88.5	Confident	50 Å²	50	35.7 Å²	35.7	26%	0.262	18%	0.178	S	C	.	.	H	α-helix	trans	-65.2	-45.4	-179.9	-171.4	69.3	0	0	0	112.2	L414 I418 Y441 I442 R448 I449	L414-L445 HydrophobicContact CD2-CD1 4.21Å; I418-L445 HydrophobicContact CD1-CB 4.29Å; I418-L445 HydrophobicContact CD1-CD1 3.99Å; Y441-L445 HydrophobicContact CE1-CD2 3.94Å; Y441-L445 WeakPolarHBondContact O-CB 3.33Å; Y441-L445 PolarHBondContact O-N 2.87Å; I442-L445 PolarHBondContact O-N 3.06Å; L445-R448 PolarHBondContact O-N 2.97Å; L445-I449 HydrophobicContact CD1-CD1 3.65Å; L445-I449 HydrophobicContact CD1-CG1 4.13Å; L445-I449 HydrophobicContact CD2-CD1 4.39Å; L445-I449 HydrophobicContact CG-CD1 3.71Å; L445-I449 HydrophobicContact CG-CG1 4.36Å; L445-I449 WeakPolarHBondContact O-CB 3.35Å; L445-I449 VanDerWaalsContact O-CG1 3.3Å; L445-I449 WeakPolarHBondContact O-CG1 3.35Å; L445-I449 PolarHBondContact O-N 2.84Å
446	L	92.1	Very high	87.4	Confident	103 Å²	103	38 Å²	38	54%	0.539	19%	0.192	S	C	.	.	H	α-helix	trans	-64.8	-47.4	-178.8	-74.9	175.6	0	0	0	112.3	I442 R448 G450	I442-L446 HydrophobicContact CG2-CD1 3.58Å; I442-L446 HydrophobicContact CG2-CG 4.19Å; I442-L446 VanDerWaalsContact O-CB 3.28Å; I442-L446 WeakPolarHBondContact O-CB 3.48Å; I442-L446 VanDerWaalsContact O-CG 3.23Å; I442-L446 WeakPolarHBondContact O-CG 3.38Å; I442-L446 PolarHBondContact O-N 3.37Å; L446-R448 VanDerWaalsContact C-N 3.28Å; L446-R448 PolarHBondContact O-N 2.95Å; L446-G450 WeakPolarHBondContact O-CA 3.35Å; L446-G450 PolarHBondContact O-N 3.41Å
447	L	92.1	Very high	86.4	Confident	46 Å²	46	45.5 Å²	45.5	24%	0.241	23%	0.225	C	C	.	.	H	α-helix	trans	-66	-35.9	179.3	-68.7	174.7	0	0	0	111.4	F443 G451 I462 Y464 S494 A497	F443-L447 WeakPolarHBondContact O-CB 3.34Å; F443-L447 VanDerWaalsContact O-CG 3.3Å; F443-L447 WeakPolarHBondContact O-CG 3.23Å; F443-L447 PolarHBondContact O-N 3.09Å; L447-G451 PolarHBondContact O-N 3.18Å; L447-I462 HydrophobicContact CD2-CD1 4.37Å; L447-Y464 PolarHBondContact O-OH 2.95Å; L447-S494 VanDerWaalsContact CB-OG 3.32Å; L447-S494 WeakPolarHBondContact CB-OG 3.42Å; L447-A497 HydrophobicContact CD1-CB 3.44Å; L447-A497 VanDerWaalsContact CD1-CB 3.44Å
448	R	89.6	Confident	85.5	Confident	7 Å²	7	49.5 Å²	49.5	3%	0.026	25%	0.246	C	C	.	.	H	α-helix	trans	-71.1	-50.6	179.1	179.3	54.3	-168.3	89.8	0.8	113.1	D413 V417 G444 L445 L446 G450 G451 G452 E453	D413-R448 VanDerWaalsContact CG-NH2 3.26Å; D413-R448 IonicContact OD1-CZ 3.5Å; D413-R448 IonicContact OD1-NE 3.69Å; D413-R448 PolarHBondContact OD1-NE 3.17Å; D413-R448 IonicContact OD1-NH2 3.43Å; D413-R448 PolarHBondContact OD1-NH2 3.3Å; D413-R448 IonicContact OD2-CZ 3.11Å; D413-R448 IonicContact OD2-NE 3.55Å; D413-R448 PolarHBondContact OD2-NE 3.4Å; D413-R448 IonicContact OD2-NH2 3.78Å; D413-R448 PolarHBondContact OD2-NH2 2.97Å; V417-R448 HydrophobicContact CG1-CB 4.14Å; V417-R448 HydrophobicContact CG2-CB 4.49Å; V417-R448 HydrophobicContact CG2-CG 4.34Å; G444-R448 WeakPolarHBondContact O-CB 3.46Å; G444-R448 PolarHBondContact O-N 3.42Å; L445-R448 PolarHBondContact O-N 2.97Å; L446-R448 VanDerWaalsContact C-N 3.28Å; L446-R448 PolarHBondContact O-N 2.95Å; R448-G450 PolarHBondContact O-N 3.43Å; R448-G451 PolarHBondContact O-N 3.31Å; R448-G452 PolarHBondContact NH1-O 3.29Å; R448-E453 IonicContact CZ-OE2 2.72Å; R448-E453 IonicContact NH1-OE2 3Å; R448-E453 IonicContact NH2-OE2 3.3Å; R448-E453 PolarHBondContact NH2-OE2 3.23Å
449	I	87.4	Confident	84.8	Confident	82 Å²	82	52.6 Å²	52.6	42%	0.421	27%	0.267	S	S	.	.	H	α-helix	trans	-64.8	-34.7	176.7	-64	178.2	0	0	0	109.8	L445 G451 G452 F461	L445-I449 HydrophobicContact CD1-CD1 3.65Å; L445-I449 HydrophobicContact CD1-CG1 4.13Å; L445-I449 HydrophobicContact CD2-CD1 4.39Å; L445-I449 HydrophobicContact CG-CD1 3.71Å; L445-I449 HydrophobicContact CG-CG1 4.36Å; L445-I449 WeakPolarHBondContact O-CB 3.35Å; L445-I449 VanDerWaalsContact O-CG1 3.3Å; L445-I449 WeakPolarHBondContact O-CG1 3.35Å; L445-I449 PolarHBondContact O-N 2.84Å; I449-G451 PolarHBondContact O-N 3.45Å; I449-G452 PolarHBondContact O-N 3.42Å; I449-F461 HydrophobicContact CG2-CE1 4.1Å
450	G	85.4	Confident	84.4	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-55.4	-36.7	175.5	0	0	0	0	0	114.4	L446 R448 G452 F461 I462	L446-G450 WeakPolarHBondContact O-CA 3.35Å; L446-G450 PolarHBondContact O-N 3.41Å; R448-G450 PolarHBondContact O-N 3.43Å; G450-G452 PolarHBondContact O-N 2.85Å; G450-F461 PolarHBondContact O-N 2.9Å; G450-F461 VanDerWaalsContact O-N 3.1Å; G450-I462 WeakPolarHBondContact O-CA 3.14Å; G450-I462 WeakPolarHBondContact O-CB 3.41Å; G450-I462 PolarHBondContact O-N 3.47Å
451	G	83.4	Confident	84	Confident	3 Å²	3	58.9 Å²	58.9	3%	0.031	29%	0.294	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69	-7.3	176.4	0	0	0	0	0	115.2	L447 R448 I449 Q486	L447-G451 PolarHBondContact O-N 3.18Å; R448-G451 PolarHBondContact O-N 3.31Å; I449-G451 PolarHBondContact O-N 3.45Å; G451-Q486 WeakPolarHBondContact O-CG 3.41Å; G451-Q486 PolarHBondContact O-NE2 2.85Å
452	G	81.7	Confident	83.6	Confident	4 Å²	4	60 Å²	60	4%	0.041	30%	0.301	C	S	.	.			trans	75.2	171.7	-176.2	0	0	0	0	0	112.9	R448 I449 G450 L458	R448-G452 PolarHBondContact NH1-O 3.29Å; I449-G452 PolarHBondContact O-N 3.42Å; G450-G452 PolarHBondContact O-N 2.85Å; G452-L458 WeakPolarHBondContact CA-O 3.3Å
453	E	78.3	Confident	83.3	Confident	9 Å²	9	62 Å²	62	4%	0.042	30%	0.304	C	S	.	.	B	Isolated β-bridge	trans	-148.3	102.5	175.8	-176.6	45.9	-104.6	0	0	110.9	L410 R448 Y455 L456 K457 L458	L410-E453 HydrophobicContact CD2-CG 3.63Å; R448-E453 IonicContact CZ-OE2 2.72Å; R448-E453 IonicContact NH1-OE2 3Å; R448-E453 IonicContact NH2-OE2 3.3Å; R448-E453 PolarHBondContact NH2-OE2 3.23Å; E453-Y455 VanDerWaalsContact C-N 3.28Å; E453-Y455 PolarHBondContact O-N 3.07Å; E453-Y455 WeakPolarHBondContact OE1-CD2 3.27Å; E453-Y455 PolarHBondContact OE1-N 2.73Å; E453-Y455 VanDerWaalsContact OE1-N 3.17Å; E453-L456 HydrophobicContact CB-CB 4.3Å; E453-L456 HydrophobicContact CG-CB 4Å; E453-L456 HydrophobicContact CG-CD1 4.03Å; E453-L456 HydrophobicContact CG-CG 3.89Å; E453-L456 PolarHBondContact O-N 2.96Å; E453-K457 PolarHBondContact O-N 3.31Å; E453-L458 HydrophobicContact CB-CB 4.12Å; E453-L458 HydrophobicContact CB-CD1 4.25Å; E453-L458 PolarHBondContact N-O 3.47Å; E453-L458 PolarHBondContact O-N 3.04Å
454	P	70.2	Confident	83	Confident	50 Å²	50	58.5 Å²	58.5	33%	0.325	29%	0.289	S	S	.	.	G	3₁₀ helix	trans	-53.4	-41	-179.8	-29.4	36.7	0	0	0	113.6	L456 K457 F483	P454-L456 VanDerWaalsContact C-N 3.28Å; P454-L456 PolarHBondContact O-N 3.42Å; P454-K457 PolarHBondContact O-N 2.9Å; P454-K457 VanDerWaalsContact O-N 3.08Å; P454-F483 HydrophobicContact CB-CB 4.02Å; P454-F483 HydrophobicContact CB-CD2 3.89Å; P454-F483 HydrophobicContact CB-CG 4.14Å; P454-F483 HydrophobicContact CG-CB 4.4Å; P454-F483 HydrophobicContact CG-CD2 3.85Å; P454-F483 HydrophobicContact CG-CG 4.48Å
455	Y	67.9	Low	82.7	Confident	111 Å²	111	63 Å²	63	44%	0.435	32%	0.318	S	S	.	.	G	3₁₀ helix	trans	-68.7	-27.1	-176.5	-63.1	-67.4	0	0	0	113.4	Y405 E453	Y405-Y455 HydrophobicContact CD1-CE1 4.35Å; Y405-Y455 AromaticContact CD1-CZ 3.91Å; Y405-Y455 WeakPolarHBondContact CD1-OH 3.5Å; Y405-Y455 HydrophobicContact CE1-CE2 4.37Å; Y405-Y455 AromaticContact CE1-CZ 3.96Å; Y405-Y455 VanDerWaalsContact CE1-OH 3.3Å; Y405-Y455 WeakPolarHBondContact CE1-OH 3.39Å; E453-Y455 VanDerWaalsContact C-N 3.28Å; E453-Y455 PolarHBondContact O-N 3.07Å; E453-Y455 WeakPolarHBondContact OE1-CD2 3.27Å; E453-Y455 PolarHBondContact OE1-N 2.73Å; E453-Y455 VanDerWaalsContact OE1-N 3.17Å
456	L	68.3	Low	82.2	Confident	81 Å²	81	62.9 Å²	62.9	42%	0.424	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-96.7	5.3	176.2	-64	179.2	0	0	0	112.4	L410 E453 P454 L458	L410-L456 HydrophobicContact CD1-CD1 4.06Å; L410-L456 HydrophobicContact CD1-CD2 3.73Å; L410-L456 HydrophobicContact CD1-CG 3.77Å; L410-L456 HydrophobicContact CD2-CD1 3.9Å; L410-L456 HydrophobicContact CD2-CG 4.2Å; E453-L456 HydrophobicContact CB-CB 4.3Å; E453-L456 HydrophobicContact CG-CB 4Å; E453-L456 HydrophobicContact CG-CD1 4.03Å; E453-L456 HydrophobicContact CG-CG 3.89Å; E453-L456 PolarHBondContact O-N 2.96Å; P454-L456 VanDerWaalsContact C-N 3.28Å; P454-L456 PolarHBondContact O-N 3.42Å; L456-L458 HydrophobicContact CB-CB 4.49Å; L456-L458 HydrophobicContact CB-CD1 3.79Å; L456-L458 HydrophobicContact CB-CG 3.79Å; L456-L458 HydrophobicContact CD1-CD1 3.87Å; L456-L458 PolarHBondContact O-N 3.43Å; L456-L458 VanDerWaalsContact O-N 3.14Å
457	K	71.9	Confident	81.8	Confident	157 Å²	157	63.7 Å²	63.7	68%	0.683	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.6	32.1	-172.1	-55.9	-172.5	177.6	-163.6	0	112.3	E453 P454 P459 E481	E453-K457 PolarHBondContact O-N 3.31Å; P454-K457 PolarHBondContact O-N 2.9Å; P454-K457 VanDerWaalsContact O-N 3.08Å; K457-P459 VanDerWaalsContact O-CD 3.31Å; K457-P459 WeakPolarHBondContact O-CD 3.44Å; K457-E481 WeakPolarHBondContact CE-OE1 3.27Å; K457-E481 IonicContact NZ-OE1 3.45Å; K457-E481 PolarHBondContact NZ-OE1 2.9Å
458	L	75.9	Confident	81.3	Confident	84 Å²	84	63.9 Å²	63.9	44%	0.44	33%	0.328	S	S	.	.	B	Isolated β-bridge	trans	-86.8	110.7	177.8	-71.7	172.7	0	0	0	108.6	G452 E453 L456	G452-L458 WeakPolarHBondContact CA-O 3.3Å; E453-L458 HydrophobicContact CB-CB 4.12Å; E453-L458 HydrophobicContact CB-CD1 4.25Å; E453-L458 PolarHBondContact N-O 3.47Å; E453-L458 PolarHBondContact O-N 3.04Å; L456-L458 HydrophobicContact CB-CB 4.49Å; L456-L458 HydrophobicContact CB-CD1 3.79Å; L456-L458 HydrophobicContact CB-CG 3.79Å; L456-L458 HydrophobicContact CD1-CD1 3.87Å; L456-L458 PolarHBondContact O-N 3.43Å; L456-L458 VanDerWaalsContact O-N 3.14Å
459	P	79.4	Confident	81	Confident	100 Å²	100	68.2 Å²	68.2	65%	0.649	35%	0.351	S	S	*	.			trans	-67.3	140.1	-179.6	27.7	-33.7	0	0	0	110.3	K457	K457-P459 VanDerWaalsContact O-CD 3.31Å; K457-P459 WeakPolarHBondContact O-CD 3.44Å
460	P	85.6	Confident	80.4	Confident	16 Å²	16	67.4 Å²	67.4	10%	0.104	35%	0.345	C	S	.	.			trans	-66.3	136.8	172.3	28	-33.4	0	0	0	110.2	Y463 V484	P460-Y463 HydrophobicContact CG-CD1 4.45Å; P460-Y463 HydrophobicContact CG-CE1 3.91Å; P460-Y463 PolarHBondContact O-OH 2.9Å; P460-V484 HydrophobicContact CG-CB 3.79Å; P460-V484 HydrophobicContact CG-CG1 3.88Å; P460-V484 HydrophobicContact CG-CG2 3.92Å
461	F	88.3	Confident	80	Confident	128 Å²	128	73.3 Å²	73.3	56%	0.561	37%	0.371	S	S	*	.	S	Bend	trans	-104.6	-12.6	165	65.6	-100.8	0	0	0	112.2	I449 G450	I449-F461 HydrophobicContact CG2-CE1 4.1Å; G450-F461 PolarHBondContact O-N 2.9Å; G450-F461 VanDerWaalsContact O-N 3.1Å
462	I	86.4	Confident	79.3	Confident	52 Å²	52	78.4 Å²	78.4	27%	0.267	39%	0.392	S	S	.	.	S	Bend	trans	-111	112.6	168.5	-53.3	-179.2	0	0	0	108	L447 G450 Y464 Q486	L447-I462 HydrophobicContact CD2-CD1 4.37Å; G450-I462 WeakPolarHBondContact O-CA 3.14Å; G450-I462 WeakPolarHBondContact O-CB 3.41Å; G450-I462 PolarHBondContact O-N 3.47Å; I462-Y464 HydrophobicContact CB-CD2 4.49Å; I462-Y464 HydrophobicContact CB-CE2 3.99Å; I462-Y464 HydrophobicContact CG2-CD1 4.37Å; I462-Y464 HydrophobicContact CG2-CD2 4.01Å; I462-Y464 HydrophobicContact CG2-CE1 4.04Å; I462-Y464 HydrophobicContact CG2-CE2 3.66Å; I462-Y464 HydrophobicContact CG2-CG 4.36Å; I462-Q486 PolarHBondContact O-NE2 3.43Å
463	Y	87.1	Confident	78.6	Confident	125 Å²	125	81.5 Å²	81.5	49%	0.49	41%	0.41	S	S	.	.			trans	-90.7	104	174.3	-67.2	-92.3	0	0	0	108.6	P460 W467 V484	P460-Y463 HydrophobicContact CG-CD1 4.45Å; P460-Y463 HydrophobicContact CG-CE1 3.91Å; P460-Y463 PolarHBondContact O-OH 2.9Å; Y463-W467 AromaticContact CD1-CD2 3.9Å; Y463-W467 HydrophobicContact CD1-CD2 3.9Å; Y463-W467 HydrophobicContact CD1-CE3 4.23Å; Y463-W467 HydrophobicContact CD1-CG 4.06Å; Y463-V484 HydrophobicContact CD1-CG1 4.48Å; Y463-V484 HydrophobicContact CE1-CG1 4.4Å; Y463-V484 HydrophobicContact CE1-CG2 4.38Å
464	Y	87.1	Confident	78	Confident	21 Å²	21	82.7 Å²	82.7	8%	0.082	42%	0.415	C	S	.	.			trans	-77.6	154.8	-179.8	-70.3	-87	0	0	0	110.6	L447 I462 G466 W467 Q486 F488 F490	L447-Y464 PolarHBondContact O-OH 2.95Å; I462-Y464 HydrophobicContact CB-CD2 4.49Å; I462-Y464 HydrophobicContact CB-CE2 3.99Å; I462-Y464 HydrophobicContact CG2-CD1 4.37Å; I462-Y464 HydrophobicContact CG2-CD2 4.01Å; I462-Y464 HydrophobicContact CG2-CE1 4.04Å; I462-Y464 HydrophobicContact CG2-CE2 3.66Å; I462-Y464 HydrophobicContact CG2-CG 4.36Å; Y464-G466 PolarHBondContact O-N 2.7Å; Y464-W467 VanDerWaalsContact O-CD1 3.3Å; Y464-W467 PolarHBondContact O-N 2.89Å; Y464-Q486 VanDerWaalsContact N-OE1 3.11Å; Y464-F488 AromaticContact CD1-CD1 3.59Å; Y464-F488 HydrophobicContact CD1-CD1 3.59Å; Y464-F488 AromaticContact CD1-CE1 3.89Å; Y464-F488 HydrophobicContact CD1-CE1 3.89Å; Y464-F488 HydrophobicContact CD1-CG 4.46Å; Y464-F488 HydrophobicContact CE1-CD1 4.42Å; Y464-F488 HydrophobicContact CE1-CE1 4.43Å; Y464-F488 AromaticContact CG-CD1 3.95Å; Y464-F488 HydrophobicContact CG-CD1 3.95Å; Y464-F490 HydrophobicContact CD1-CB 4.05Å; Y464-F490 HydrophobicContact CD2-CB 3.69Å; Y464-F490 HydrophobicContact CD2-CD2 4.38Å; Y464-F490 HydrophobicContact CD2-CG 4.08Å; Y464-F490 HydrophobicContact CE1-CB 4.06Å; Y464-F490 HydrophobicContact CE2-CB 3.69Å; Y464-F490 AromaticContact CE2-CD2 3.91Å; Y464-F490 HydrophobicContact CE2-CD2 3.91Å; Y464-F490 HydrophobicContact CE2-CG 4.02Å; Y464-F490 HydrophobicContact CG-CB 3.87Å
465	P	86.6	Confident	77.4	Confident	94 Å²	94	86.1 Å²	86.1	61%	0.61	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.7	128.9	-177.8	-26.8	35.3	0	0	0	113	F488	P465-F488 HydrophobicContact CB-CD2 4.48Å; P465-F488 HydrophobicContact CG-CD2 4.48Å; P465-F488 WeakPolarHBondContact O-CB 3.24Å
466	G	80.7	Confident	77	Confident	48 Å²	48	86.4 Å²	86.4	50%	0.495	44%	0.438	S	S	.	.	T	Hydrogen-bonded Turn	trans	83.5	23.1	-178.3	0	0	0	0	0	114.8	Y464 R487	Y464-G466 PolarHBondContact O-N 2.7Å; G466-R487 WeakPolarHBondContact O-CB 3.27Å
467	W	84.1	Confident	76.6	Confident	119 Å²	119	85.8 Å²	85.8	45%	0.451	44%	0.44	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-62.5	139.6	166.8	66.3	-89.8	0	0	0	111.1	Y463 Y464 I469 V484 Q485	Y463-W467 AromaticContact CD1-CD2 3.9Å; Y463-W467 HydrophobicContact CD1-CD2 3.9Å; Y463-W467 HydrophobicContact CD1-CE3 4.23Å; Y463-W467 HydrophobicContact CD1-CG 4.06Å; Y464-W467 VanDerWaalsContact O-CD1 3.3Å; Y464-W467 PolarHBondContact O-N 2.89Å; W467-I469 HydrophobicContact CE3-CG1 4.36Å; W467-I469 HydrophobicContact CZ3-CD1 4.1Å; W467-I469 HydrophobicContact CZ3-CG1 3.86Å; W467-V484 HydrophobicContact CB-CG1 4.19Å; W467-V484 HydrophobicContact CE3-CG1 4.41Å; W467-Q485 WeakPolarHBondContact CA-O 3.37Å
468	V	82.1	Confident	76.1	Confident	50 Å²	50	80.8 Å²	80.8	30%	0.303	43%	0.434	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.3	147	177.2	-176	0	0	0	0	108.6	Q485	V468-Q485 PolarHBondContact N-O 3.35Å; V468-Q485 PolarHBondContact O-N 3.01Å
469	I	82.5	Confident	75.7	Confident	99 Å²	99	81.6 Å²	81.6	51%	0.508	44%	0.439	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.4	112.6	169.5	-57.5	176.8	0	0	0	107	W467 Y482	W467-I469 HydrophobicContact CE3-CG1 4.36Å; W467-I469 HydrophobicContact CZ3-CD1 4.1Å; W467-I469 HydrophobicContact CZ3-CG1 3.86Å; I469-Y482 HydrophobicContact CG2-CD1 3.9Å; I469-Y482 HydrophobicContact CG2-CG 4.46Å
470	E	75.1	Confident	75.4	Confident	65 Å²	65	79.7 Å²	79.7	30%	0.304	43%	0.425	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93	145.4	172.5	-72.1	-158.6	146.9	0	0	110.5	Y482 F483 Q485	E470-Y482 WeakPolarHBondContact O-CA 3.22Å; E470-F483 HydrophobicContact CB-CE1 3.93Å; E470-F483 HydrophobicContact CB-CE2 3.98Å; E470-F483 HydrophobicContact CB-CZ 3.63Å; E470-F483 HydrophobicContact CG-CZ 4.46Å; E470-F483 PolarHBondContact N-O 2.89Å; E470-F483 PolarHBondContact O-N 3.33Å; E470-F483 VanDerWaalsContact O-N 3.1Å; E470-F483 VanDerWaalsContact OE2-CZ 3.27Å; E470-F483 WeakPolarHBondContact OE2-CZ 3.26Å; E470-Q485 VanDerWaalsContact CD-CD 3.49Å; E470-Q485 HydrophobicContact CG-CB 4.1Å; E470-Q485 PolarHBondContact OE1-OE1 2.94Å; E470-Q485 VanDerWaalsContact OE1-OE1 3.1Å; E470-Q485 PolarHBondContact OE2-NE2 3.04Å
471	K	77.1	Confident	74.7	Confident	124 Å²	124	82 Å²	82	54%	0.539	43%	0.434	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.9	111	178.5	-173.5	-166.9	-175.3	-166.3	0	108	V473 V480 Y482	K471-V473 HydrophobicContact CD-CG2 3.93Å; K471-V473 HydrophobicContact CG-CG2 4.08Å; K471-V480 HydrophobicContact CD-CG1 3.95Å; K471-V480 HydrophobicContact CG-CG1 3.45Å; K471-V480 VanDerWaalsContact CG-CG1 3.45Å; K471-Y482 HydrophobicContact CB-CD1 4.36Å; K471-Y482 HydrophobicContact CB-CE1 4.18Å; K471-Y482 HydrophobicContact CD-CE1 4.41Å; K471-Y482 HydrophobicContact CG-CD1 4.39Å; K471-Y482 HydrophobicContact CG-CE1 3.93Å
472	K	68.5	Low	74	Confident	109 Å²	109	83.1 Å²	83.1	47%	0.474	44%	0.436	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.4	120.1	167.3	-160.6	174.6	179.6	-175.2	0	108.6	V480 E481 F483	K472-V480 WeakPolarHBondContact O-CA 3.4Å; K472-E481 HydrophobicContact CB-CB 4.48Å; K472-E481 PolarHBondContact N-O 3.34Å; K472-E481 PolarHBondContact O-N 2.91Å; K472-F483 HydrophobicContact CB-CE1 4.09Å
473	V	68.1	Low	73.5	Confident	70 Å²	70	83 Å²	83	42%	0.424	43%	0.433	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.7	115.3	174.8	-176.1	0	0	0	0	107.5	K471 L475 V480	K471-V473 HydrophobicContact CD-CG2 3.93Å; K471-V473 HydrophobicContact CG-CG2 4.08Å; V473-L475 PolarHBondContact O-N 2.87Å; V473-V480 HydrophobicContact CG2-CG2 4.37Å
474	H	64.3	Low	73	Confident	34 Å²	34	78.6 Å²	78.6	16%	0.157	42%	0.419	C	S	.	.			trans	-75.1	112	172.1	-71.9	-82.3	0	0	0	108.7	E316 I476 S477 G478 D479	E316-H474 VanDerWaalsContact CD-ND1 3.27Å; E316-H474 VanDerWaalsContact OE1-CA 3.3Å; E316-H474 WeakPolarHBondContact OE1-CA 3.37Å; E316-H474 WeakPolarHBondContact OE1-CB 3.44Å; E316-H474 IonicContact OE1-CE1 2.66Å; E316-H474 IonicContact OE1-CG 2.69Å; E316-H474 IonicContact OE1-ND1 2.66Å; E316-H474 PolarHBondContact OE1-ND1 3.28Å; E316-H474 IonicContact OE2-CE1 3.39Å; E316-H474 IonicContact OE2-ND1 3.88Å; E316-H474 PolarHBondContact OE2-ND1 2.87Å; H474-I476 VanDerWaalsContact C-N 3.28Å; H474-I476 PolarHBondContact O-N 3.29Å; H474-S477 WeakPolarHBondContact CB-OG 3.19Å; H474-G478 VanDerWaalsContact O-CA 3.24Å; H474-G478 WeakPolarHBondContact O-CA 3.37Å; H474-G478 PolarHBondContact O-N 2.82Å; H474-D479 HydrophobicContact CB-CB 4.45Å; H474-D479 PolarHBondContact N-O 3.43Å
475	L	58.1	Low	72.7	Confident	121 Å²	121	79 Å²	79	63%	0.634	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.1	-28.6	-173.4	-74.3	165.7	0	0	0	112.3	D314 V473	D314-L475 HydrophobicContact CB-CD1 4.31Å; V473-L475 PolarHBondContact O-N 2.87Å
476	I	58.9	Low	72.6	Confident	118 Å²	118	75 Å²	75	61%	0.605	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.4	-47.2	179.9	-61.2	173.2	0	0	0	111.5	K315 H474	K315-I476 HydrophobicContact CB-CD1 4.29Å; K315-I476 WeakPolarHBondContact O-CD1 3.5Å; H474-I476 VanDerWaalsContact C-N 3.28Å; H474-I476 PolarHBondContact O-N 3.29Å
477	S	60.7	Low	72.9	Confident	67 Å²	67	74.8 Å²	74.8	47%	0.469	38%	0.38	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-19	-177	72.1	0	0	0	0	113.5	H474 D479	H474-S477 WeakPolarHBondContact CB-OG 3.19Å; S477-D479 VanDerWaalsContact CB-OD2 3.3Å; S477-D479 WeakPolarHBondContact CB-OD2 3.43Å; S477-D479 PolarHBondContact O-N 3.44Å; S477-D479 WeakPolarHBondContact OG-CB 3.33Å; S477-D479 PolarHBondContact OG-N 3.29Å; S477-D479 PolarHBondContact OG-OD2 3.39Å
478	G	60.9	Low	73.1	Confident	53 Å²	53	72.1 Å²	72.1	55%	0.546	37%	0.371	S	S	.	.			trans	74.7	2.2	-172.6	0	0	0	0	0	113.7	H474	H474-G478 VanDerWaalsContact O-CA 3.24Å; H474-G478 WeakPolarHBondContact O-CA 3.37Å; H474-G478 PolarHBondContact O-N 2.82Å
479	D	68.8	Low	73.5	Confident	101 Å²	101	70.9 Å²	70.9	54%	0.54	36%	0.364	S	S	.	.			trans	-72	139.2	-179.1	-65.4	-47.1	0	0	0	111.1	H474 S477	H474-D479 HydrophobicContact CB-CB 4.45Å; H474-D479 PolarHBondContact N-O 3.43Å; S477-D479 VanDerWaalsContact CB-OD2 3.3Å; S477-D479 WeakPolarHBondContact CB-OD2 3.43Å; S477-D479 PolarHBondContact O-N 3.44Å; S477-D479 WeakPolarHBondContact OG-CB 3.33Å; S477-D479 PolarHBondContact OG-N 3.29Å; S477-D479 PolarHBondContact OG-OD2 3.39Å
480	V	72.9	Confident	73.9	Confident	59 Å²	59	66.6 Å²	66.6	36%	0.358	34%	0.342	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.1	109.6	175.3	180	0	0	0	0	108.4	K471 K472 V473 Y482	K471-V480 HydrophobicContact CD-CG1 3.95Å; K471-V480 HydrophobicContact CG-CG1 3.45Å; K471-V480 VanDerWaalsContact CG-CG1 3.45Å; K472-V480 WeakPolarHBondContact O-CA 3.4Å; V473-V480 HydrophobicContact CG2-CG2 4.37Å; V480-Y482 HydrophobicContact CB-CE2 4.37Å; V480-Y482 HydrophobicContact CG1-CD2 4.08Å; V480-Y482 HydrophobicContact CG1-CE1 4.23Å; V480-Y482 HydrophobicContact CG1-CE2 3.5Å; V480-Y482 VanDerWaalsContact CG1-CE2 3.5Å
481	E	69.6	Low	74.7	Confident	64 Å²	64	64.1 Å²	64.1	30%	0.299	33%	0.33	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.2	122.6	173.1	-165.9	166.2	-141.2	0	0	109.4	K457 K472	K457-E481 WeakPolarHBondContact CE-OE1 3.27Å; K457-E481 IonicContact NZ-OE1 3.45Å; K457-E481 PolarHBondContact NZ-OE1 2.9Å; K472-E481 HydrophobicContact CB-CB 4.48Å; K472-E481 PolarHBondContact N-O 3.34Å; K472-E481 PolarHBondContact O-N 2.91Å
482	Y	73.3	Confident	75.5	Confident	153 Å²	153	59 Å²	59	60%	0.6	31%	0.31	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-97.9	123	171.4	-64.8	-84.7	0	0	0	108.3	I469 E470 K471 V480	I469-Y482 HydrophobicContact CG2-CD1 3.9Å; I469-Y482 HydrophobicContact CG2-CG 4.46Å; E470-Y482 WeakPolarHBondContact O-CA 3.22Å; K471-Y482 HydrophobicContact CB-CD1 4.36Å; K471-Y482 HydrophobicContact CB-CE1 4.18Å; K471-Y482 HydrophobicContact CD-CE1 4.41Å; K471-Y482 HydrophobicContact CG-CD1 4.39Å; K471-Y482 HydrophobicContact CG-CE1 3.93Å; V480-Y482 HydrophobicContact CB-CE2 4.37Å; V480-Y482 HydrophobicContact CG1-CD2 4.08Å; V480-Y482 HydrophobicContact CG1-CE1 4.23Å; V480-Y482 HydrophobicContact CG1-CE2 3.5Å; V480-Y482 VanDerWaalsContact CG1-CE2 3.5Å
483	F	76.1	Confident	76.7	Confident	49 Å²	49	56.7 Å²	56.7	22%	0.215	31%	0.305	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.9	148.9	173.4	66.9	-86.5	0	0	0	110.7	P454 E470 K472 Q485	P454-F483 HydrophobicContact CB-CB 4.02Å; P454-F483 HydrophobicContact CB-CD2 3.89Å; P454-F483 HydrophobicContact CB-CG 4.14Å; P454-F483 HydrophobicContact CG-CB 4.4Å; P454-F483 HydrophobicContact CG-CD2 3.85Å; P454-F483 HydrophobicContact CG-CG 4.48Å; E470-F483 HydrophobicContact CB-CE1 3.93Å; E470-F483 HydrophobicContact CB-CE2 3.98Å; E470-F483 HydrophobicContact CB-CZ 3.63Å; E470-F483 HydrophobicContact CG-CZ 4.46Å; E470-F483 PolarHBondContact N-O 2.89Å; E470-F483 PolarHBondContact O-N 3.33Å; E470-F483 VanDerWaalsContact O-N 3.1Å; E470-F483 VanDerWaalsContact OE2-CZ 3.27Å; E470-F483 WeakPolarHBondContact OE2-CZ 3.26Å; K472-F483 HydrophobicContact CB-CE1 4.09Å; F483-Q485 HydrophobicContact CD2-CB 4.45Å; F483-Q485 HydrophobicContact CE2-CB 4.09Å; F483-Q485 HydrophobicContact CE2-CG 4.43Å
484	V	78.3	Confident	77.9	Confident	32 Å²	32	53.3 Å²	53.3	19%	0.194	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.8	116.5	176.6	-179	0	0	0	0	107.8	P460 Y463 W467	P460-V484 HydrophobicContact CG-CB 3.79Å; P460-V484 HydrophobicContact CG-CG1 3.88Å; P460-V484 HydrophobicContact CG-CG2 3.92Å; Y463-V484 HydrophobicContact CD1-CG1 4.48Å; Y463-V484 HydrophobicContact CE1-CG1 4.4Å; Y463-V484 HydrophobicContact CE1-CG2 4.38Å; W467-V484 HydrophobicContact CB-CG1 4.19Å; W467-V484 HydrophobicContact CE3-CG1 4.41Å
485	Q	80.1	Confident	79.4	Confident	31 Å²	31	52.5 Å²	52.5	15%	0.145	28%	0.281	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.6	123.9	173.3	-163.9	-169.9	46.8	0	0	109.1	L241 W467 V468 E470 F483	L241-Q485 HydrophobicContact CD2-CG 4.49Å; W467-Q485 WeakPolarHBondContact CA-O 3.37Å; V468-Q485 PolarHBondContact N-O 3.35Å; V468-Q485 PolarHBondContact O-N 3.01Å; E470-Q485 VanDerWaalsContact CD-CD 3.49Å; E470-Q485 HydrophobicContact CG-CB 4.1Å; E470-Q485 PolarHBondContact OE1-OE1 2.94Å; E470-Q485 VanDerWaalsContact OE1-OE1 3.1Å; E470-Q485 PolarHBondContact OE2-NE2 3.04Å; F483-Q485 HydrophobicContact CD2-CB 4.45Å; F483-Q485 HydrophobicContact CE2-CB 4.09Å; F483-Q485 HydrophobicContact CE2-CG 4.43Å
486	Q	83.9	Confident	81.3	Confident	10 Å²	10	50.1 Å²	50.1	5%	0.047	27%	0.271	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.2	112.1	176.8	-56.5	-86.5	20.8	0	0	108.3	G451 I462 Y464 F490	G451-Q486 WeakPolarHBondContact O-CG 3.41Å; G451-Q486 PolarHBondContact O-NE2 2.85Å; I462-Q486 PolarHBondContact O-NE2 3.43Å; Y464-Q486 VanDerWaalsContact N-OE1 3.11Å; Q486-F490 HydrophobicContact CB-CD1 3.72Å; Q486-F490 HydrophobicContact CB-CE1 3.73Å; Q486-F490 HydrophobicContact CG-CD1 4.25Å; Q486-F490 HydrophobicContact CG-CE1 4.07Å
487	R	86.5	Confident	83	Confident	43 Å²	43	45.7 Å²	45.7	16%	0.162	25%	0.252	C	S	.	.			trans	-84.3	-20.3	175.3	-66.6	177.6	171	-179.4	-9.1	113.3	E237 D238 W240 L241 G466	E237-R487 IonicContact OE1-NH2 3.27Å; E237-R487 PolarHBondContact OE1-NH2 3.42Å; E237-R487 IonicContact OE2-CZ 2.6Å; E237-R487 VanDerWaalsContact OE2-CZ 3.3Å; E237-R487 IonicContact OE2-NH1 3.74Å; E237-R487 PolarHBondContact OE2-NH1 2.95Å; E237-R487 IonicContact OE2-NH2 3.47Å; E237-R487 PolarHBondContact OE2-NH2 3.45Å; E237-R487 VanDerWaalsContact OE2-NH2 3.11Å; D238-R487 IonicContact OD1-CZ 3.4Å; D238-R487 IonicContact OD1-NE 3.12Å; D238-R487 PolarHBondContact OD1-NE 3.02Å; D238-R487 IonicContact OD1-NH2 3.36Å; W240-R487 VanDerWaalsContact CB-O 3.29Å; W240-R487 WeakPolarHBondContact CB-O 3.47Å; L241-R487 PolarHBondContact N-O 3.25Å; G466-R487 WeakPolarHBondContact O-CB 3.27Å
488	F	88.6	Confident	84.7	Confident	62 Å²	62	42.5 Å²	42.5	27%	0.272	23%	0.23	S	C	.	.	S	Bend	trans	-62.8	142.3	171.7	-170.9	-104.2	0	0	0	110.3	Y464 P465 F490 V493	Y464-F488 AromaticContact CD1-CD1 3.59Å; Y464-F488 HydrophobicContact CD1-CD1 3.59Å; Y464-F488 AromaticContact CD1-CE1 3.89Å; Y464-F488 HydrophobicContact CD1-CE1 3.89Å; Y464-F488 HydrophobicContact CD1-CG 4.46Å; Y464-F488 HydrophobicContact CE1-CD1 4.42Å; Y464-F488 HydrophobicContact CE1-CE1 4.43Å; Y464-F488 AromaticContact CG-CD1 3.95Å; Y464-F488 HydrophobicContact CG-CD1 3.95Å; P465-F488 HydrophobicContact CB-CD2 4.48Å; P465-F488 HydrophobicContact CG-CD2 4.48Å; P465-F488 WeakPolarHBondContact O-CB 3.24Å; F488-F490 HydrophobicContact CD1-CB 3.89Å; F488-F490 PolarHBondContact O-N 3.42Å; F488-V493 HydrophobicContact CE1-CB 4.12Å; F488-V493 HydrophobicContact CE1-CG1 4.4Å; F488-V493 HydrophobicContact CE1-CG2 3.64Å; F488-V493 HydrophobicContact CZ-CG2 3.86Å
489	P	91.3	Very high	86.4	Confident	24 Å²	24	42.6 Å²	42.6	16%	0.156	22%	0.216	C	C	.	.			trans	-78.4	58.8	-178.1	34.1	-32.6	0	0	0	111.2	W240 D244 K491 S492 V493	W240-P489 HydrophobicContact CB-CB 4.5Å; W240-P489 HydrophobicContact CB-CG 4.3Å; W240-P489 HydrophobicContact CG-CG 4.48Å; D244-P489 HydrophobicContact CB-CB 3.69Å; D244-P489 VanDerWaalsContact CG-C 3.49Å; D244-P489 WeakPolarHBondContact OD2-CA 3.22Å; P489-K491 VanDerWaalsContact C-N 3.26Å; P489-K491 PolarHBondContact O-N 3.18Å; P489-S492 PolarHBondContact O-N 3.46Å; P489-V493 WeakPolarHBondContact O-CG2 3.41Å; P489-V493 PolarHBondContact O-N 3.15Å
490	F	90.4	Very high	87.7	Confident	9 Å²	9	42.2 Å²	42.2	4%	0.039	21%	0.213	C	C	.	.	H	α-helix	trans	-68.6	-24.3	-168.1	78.7	-83.3	0	0	0	112.6	D244 Y464 Q486 F488 S494	D244-F490 PolarHBondContact OD2-N 3.39Å; Y464-F490 HydrophobicContact CD1-CB 4.05Å; Y464-F490 HydrophobicContact CD2-CB 3.69Å; Y464-F490 HydrophobicContact CD2-CD2 4.38Å; Y464-F490 HydrophobicContact CD2-CG 4.08Å; Y464-F490 HydrophobicContact CE1-CB 4.06Å; Y464-F490 HydrophobicContact CE2-CB 3.69Å; Y464-F490 AromaticContact CE2-CD2 3.91Å; Y464-F490 HydrophobicContact CE2-CD2 3.91Å; Y464-F490 HydrophobicContact CE2-CG 4.02Å; Y464-F490 HydrophobicContact CG-CB 3.87Å; Q486-F490 HydrophobicContact CB-CD1 3.72Å; Q486-F490 HydrophobicContact CB-CE1 3.73Å; Q486-F490 HydrophobicContact CG-CD1 4.25Å; Q486-F490 HydrophobicContact CG-CE1 4.07Å; F488-F490 HydrophobicContact CD1-CB 3.89Å; F488-F490 PolarHBondContact O-N 3.42Å; F490-S494 VanDerWaalsContact O-CB 3.29Å; F490-S494 WeakPolarHBondContact O-CB 3.42Å; F490-S494 PolarHBondContact O-N 3.34Å; F490-S494 PolarHBondContact O-OG 2.82Å
491	K	91.3	Very high	88.8	Confident	14 Å²	14	39.8 Å²	39.8	6%	0.061	20%	0.199	C	C	.	.	H	α-helix	trans	-72.8	-45.8	179.8	-54.1	176.3	-159	-141.2	0	110	D244 L248 Y409 Y416 V417 P489 V493 S494 M495	D244-K491 WeakPolarHBondContact OD2-CB 3.19Å; D244-K491 WeakPolarHBondContact OD2-CG 3.31Å; D244-K491 PolarHBondContact OD2-N 3.19Å; L248-K491 HydrophobicContact CD1-CD 3.75Å; Y409-K491 HydrophobicContact CE1-CD 4.32Å; Y409-K491 WeakPolarHBondContact OH-CD 3.41Å; Y409-K491 WeakPolarHBondContact OH-CE 3.18Å; Y409-K491 PolarHBondContact OH-NZ 3.35Å; Y416-K491 HydrophobicContact CD1-CB 4.44Å; Y416-K491 HydrophobicContact CE1-CB 4.29Å; V417-K491 HydrophobicContact CG2-CB 4.49Å; P489-K491 VanDerWaalsContact C-N 3.26Å; P489-K491 PolarHBondContact O-N 3.18Å; K491-V493 VanDerWaalsContact C-N 3.35Å; K491-S494 WeakPolarHBondContact O-CB 3.39Å; K491-S494 PolarHBondContact O-N 3.45Å; K491-M495 WeakPolarHBondContact O-CB 3.31Å; K491-M495 PolarHBondContact O-N 3.16Å
492	S	94.2	Very high	90	Very high	16 Å²	16	36.8 Å²	36.8	11%	0.112	19%	0.185	C	C	.	.	H	α-helix	trans	-64.5	-39.5	173.8	-62.5	0	0	0	0	111.5	D244 Y416 P489 M495 V496	D244-S492 WeakPolarHBondContact OD1-CB 3.46Å; D244-S492 PolarHBondContact OD1-N 3.31Å; D244-S492 PolarHBondContact OD1-OG 3.49Å; Y416-S492 WeakPolarHBondContact OH-CA 3.49Å; Y416-S492 WeakPolarHBondContact OH-CB 3.16Å; Y416-S492 PolarHBondContact OH-OG 2.94Å; P489-S492 PolarHBondContact O-N 3.46Å; S492-M495 PolarHBondContact O-N 3.23Å; S492-V496 WeakPolarHBondContact O-CG2 3.29Å; S492-V496 PolarHBondContact O-N 3.02Å
493	V	94	Very high	91	Very high	60 Å²	60	31 Å²	31	36%	0.364	17%	0.165	S	C	.	.	H	α-helix	trans	-64.1	-40.9	172.7	173.6	0	0	0	0	111.6	F488 P489 K491 M495 V496 A497	F488-V493 HydrophobicContact CE1-CB 4.12Å; F488-V493 HydrophobicContact CE1-CG1 4.4Å; F488-V493 HydrophobicContact CE1-CG2 3.64Å; F488-V493 HydrophobicContact CZ-CG2 3.86Å; P489-V493 WeakPolarHBondContact O-CG2 3.41Å; P489-V493 PolarHBondContact O-N 3.15Å; K491-V493 VanDerWaalsContact C-N 3.35Å; V493-M495 VanDerWaalsContact C-N 3.34Å; V493-M495 PolarHBondContact O-N 2.93Å; V493-V496 PolarHBondContact O-N 3.5Å; V493-A497 VanDerWaalsContact O-CB 3.25Å; V493-A497 WeakPolarHBondContact O-CB 3.21Å; V493-A497 PolarHBondContact O-N 3.34Å
494	S	94.4	Very high	91.9	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.6	-40.6	176.1	-59.3	0	0	0	0	111.7	L447 F490 K491 A497 S498	L447-S494 VanDerWaalsContact CB-OG 3.32Å; L447-S494 WeakPolarHBondContact CB-OG 3.42Å; F490-S494 VanDerWaalsContact O-CB 3.29Å; F490-S494 WeakPolarHBondContact O-CB 3.42Å; F490-S494 PolarHBondContact O-N 3.34Å; F490-S494 PolarHBondContact O-OG 2.82Å; K491-S494 WeakPolarHBondContact O-CB 3.39Å; K491-S494 PolarHBondContact O-N 3.45Å; S494-A497 PolarHBondContact O-N 2.88Å; S494-S498 VanDerWaalsContact O-CB 3.31Å; S494-S498 WeakPolarHBondContact O-CB 3.48Å; S494-S498 PolarHBondContact O-N 3.44Å
495	M	96.1	Very high	92.7	Very high	17 Å²	17	34.9 Å²	34.9	8%	0.084	19%	0.187	C	C	.	.	H	α-helix	trans	-62.4	-48.4	175.1	-178.4	-77.4	-71.3	0	0	111.4	L251 Y416 F420 P421 K491 S492 V493 A497 S498 F499	L251-M495 HydrophobicContact CD1-CE 4.19Å; Y416-M495 HydrophobicContact CD2-CG 4.08Å; Y416-M495 HydrophobicContact CE1-CB 4.14Å; Y416-M495 HydrophobicContact CE1-CG 4.48Å; Y416-M495 HydrophobicContact CE2-CB 4.22Å; Y416-M495 HydrophobicContact CE2-CE 3.85Å; Y416-M495 HydrophobicContact CE2-CG 3.68Å; Y416-M495 HydrophobicContact CE2-SD 4.47Å; Y416-M495 VanDerWaalsContact O-CG 3.28Å; Y416-M495 WeakPolarHBondContact O-CG 3.09Å; Y416-M495 WeakPolarHBondContact OH-CE 3.32Å; F420-M495 HydrophobicContact CD1-CG 4.23Å; F420-M495 HydrophobicContact CD1-SD 3.97Å; F420-M495 HydrophobicContact CE1-SD 4.3Å; P421-M495 HydrophobicContact CG-CB 4.49Å; P421-M495 HydrophobicContact CG-CG 3.64Å; P421-M495 WeakPolarHBondContact CG-O 3.41Å; P421-M495 HydrophobicContact CG-SD 3.95Å; K491-M495 WeakPolarHBondContact O-CB 3.31Å; K491-M495 PolarHBondContact O-N 3.16Å; S492-M495 PolarHBondContact O-N 3.23Å; V493-M495 VanDerWaalsContact C-N 3.34Å; V493-M495 PolarHBondContact O-N 2.93Å; M495-A497 PolarHBondContact O-N 2.86Å; M495-S498 WeakPolarHBondContact O-CB 3.48Å; M495-S498 PolarHBondContact O-N 3.45Å; M495-F499 PolarHBondContact O-N 3.01Å
496	V	96.4	Very high	93.2	Very high	70 Å²	70	33.4 Å²	33.4	42%	0.424	18%	0.18	S	C	.	.	H	α-helix	trans	-64.2	-41.6	177	171.7	0	0	0	0	111.1	S492 V493 S498 F499 L500	S492-V496 WeakPolarHBondContact O-CG2 3.29Å; S492-V496 PolarHBondContact O-N 3.02Å; V493-V496 PolarHBondContact O-N 3.5Å; V496-S498 VanDerWaalsContact C-N 3.34Å; V496-S498 PolarHBondContact O-N 3.43Å; V496-F499 PolarHBondContact O-N 3.46Å; V496-L500 HydrophobicContact CG1-CD1 3.9Å; V496-L500 HydrophobicContact CG1-CG 4.23Å; V496-L500 WeakPolarHBondContact O-CB 3.44Å; V496-L500 WeakPolarHBondContact O-CG 3.26Å; V496-L500 PolarHBondContact O-N 2.89Å
497	A	95.7	Very high	93.6	Very high	26 Å²	26	38.1 Å²	38.1	22%	0.215	20%	0.198	C	C	.	.	H	α-helix	trans	-62.5	-41.1	175.9	0	0	0	0	0	111.9	L447 V493 S494 M495 L500 A501	L447-A497 HydrophobicContact CD1-CB 3.44Å; L447-A497 VanDerWaalsContact CD1-CB 3.44Å; V493-A497 VanDerWaalsContact O-CB 3.25Å; V493-A497 WeakPolarHBondContact O-CB 3.21Å; V493-A497 PolarHBondContact O-N 3.34Å; S494-A497 PolarHBondContact O-N 2.88Å; M495-A497 PolarHBondContact O-N 2.86Å; A497-L500 PolarHBondContact O-N 3.41Å; A497-A501 WeakPolarHBondContact O-CB 3.46Å; A497-A501 PolarHBondContact O-N 2.93Å
498	S	96.3	Very high	93.8	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-59.7	-46.6	172.5	175.1	0	0	0	0	111.3	V417 A440 S494 M495 V496 A501 N502	V417-S498 WeakPolarHBondContact O-CB 3.43Å; V417-S498 PolarHBondContact O-OG 3.47Å; A440-S498 WeakPolarHBondContact CB-O 3.27Å; A440-S498 PolarHBondContact O-OG 3.03Å; S494-S498 VanDerWaalsContact O-CB 3.31Å; S494-S498 WeakPolarHBondContact O-CB 3.48Å; S494-S498 PolarHBondContact O-N 3.44Å; M495-S498 WeakPolarHBondContact O-CB 3.48Å; M495-S498 PolarHBondContact O-N 3.45Å; V496-S498 VanDerWaalsContact C-N 3.34Å; V496-S498 PolarHBondContact O-N 3.43Å; S498-A501 PolarHBondContact O-N 3.36Å; S498-N502 PolarHBondContact O-N 3.45Å
499	F	96.6	Very high	93.8	Very high	55 Å²	55	37.8 Å²	37.8	24%	0.241	20%	0.203	C	C	.	.	H	α-helix	trans	-60.6	-50.6	176.1	179.5	-106.9	0	0	0	112.5	P421 L424 V429 M495 V496 A501 N502 V503	P421-F499 HydrophobicContact CB-CB 3.87Å; P421-F499 HydrophobicContact CB-CD2 4.48Å; P421-F499 HydrophobicContact CG-CB 4.43Å; L424-F499 HydrophobicContact CB-CD2 4.14Å; L424-F499 HydrophobicContact CB-CE2 3.87Å; L424-F499 HydrophobicContact CD1-CD2 4.38Å; L424-F499 HydrophobicContact CD1-CE2 4.49Å; V429-F499 HydrophobicContact CG2-CE2 4.06Å; V429-F499 HydrophobicContact CG2-CZ 3.97Å; M495-F499 PolarHBondContact O-N 3.01Å; V496-F499 PolarHBondContact O-N 3.46Å; F499-A501 VanDerWaalsContact C-N 3.34Å; F499-A501 PolarHBondContact O-N 3.34Å; F499-N502 WeakPolarHBondContact O-CB 3.45Å; F499-N502 PolarHBondContact O-N 3.17Å; F499-N502 VanDerWaalsContact O-N 3.15Å; F499-V503 HydrophobicContact CE1-CG2 4.27Å; F499-V503 HydrophobicContact CE2-CG2 4.29Å; F499-V503 HydrophobicContact CZ-CG2 4.06Å; F499-V503 WeakPolarHBondContact O-CG2 3.21Å; F499-V503 PolarHBondContact O-N 2.9Å; F499-V503 VanDerWaalsContact O-N 3.15Å
500	L	96.4	Very high	93.5	Very high	93 Å²	93	38.5 Å²	38.5	49%	0.487	20%	0.203	S	C	.	.	H	α-helix	trans	-63.5	-40.1	179.6	-69.2	176.5	0	0	0	111.7	V496 A497 N502 V503 V504	V496-L500 HydrophobicContact CG1-CD1 3.9Å; V496-L500 HydrophobicContact CG1-CG 4.23Å; V496-L500 WeakPolarHBondContact O-CB 3.44Å; V496-L500 WeakPolarHBondContact O-CG 3.26Å; V496-L500 PolarHBondContact O-N 2.89Å; A497-L500 PolarHBondContact O-N 3.41Å; L500-N502 VanDerWaalsContact C-N 3.29Å; L500-N502 PolarHBondContact O-N 3.05Å; L500-V503 PolarHBondContact O-N 3.35Å; L500-V504 VanDerWaalsContact O-CB 3.32Å; L500-V504 WeakPolarHBondContact O-CB 3.35Å; L500-V504 VanDerWaalsContact O-CG2 3.26Å; L500-V504 WeakPolarHBondContact O-CG2 3.35Å; L500-V504 PolarHBondContact O-N 3.04Å
501	A	95.6	Very high	93.3	Very high	8 Å²	8	44.8 Å²	44.8	7%	0.066	23%	0.228	C	C	.	.	H	α-helix	trans	-60.2	-40.5	174.5	0	0	0	0	0	111.2	F443 A497 S498 F499 F505	F443-A501 HydrophobicContact CB-CB 4.12Å; F443-A501 HydrophobicContact CD2-CB 4.03Å; F443-A501 HydrophobicContact CG-CB 4.09Å; A497-A501 WeakPolarHBondContact O-CB 3.46Å; A497-A501 PolarHBondContact O-N 2.93Å; S498-A501 PolarHBondContact O-N 3.36Å; F499-A501 VanDerWaalsContact C-N 3.34Å; F499-A501 PolarHBondContact O-N 3.34Å; A501-F505 HydrophobicContact CB-CD2 4.44Å; A501-F505 WeakPolarHBondContact O-CB 3.44Å; A501-F505 WeakPolarHBondContact O-CD2 3.45Å; A501-F505 PolarHBondContact O-N 3Å
502	N	95.3	Very high	93.2	Very high	0 Å²	0	46 Å²	46	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-58.7	-54.7	176.3	-161	-2.1	0	0	0	111.1	Y124 Q422 S425 G436 S437 A440 S498 F499 L500 S506	Y124-N502 PolarHBondContact OH-ND2 2.93Å; Q422-N502 PolarHBondContact OE1-ND2 3.08Å; S425-N502 WeakPolarHBondContact CB-ND2 3.25Å; S425-N502 PolarHBondContact OG-ND2 2.9Å; G436-N502 WeakPolarHBondContact CA-O 3.37Å; G436-N502 WeakPolarHBondContact CA-OD1 3.34Å; G436-N502 WeakPolarHBondContact O-CA 3.15Å; G436-N502 PolarHBondContact O-OD1 3.27Å; S437-N502 PolarHBondContact N-OD1 3.14Å; S437-N502 VanDerWaalsContact N-OD1 3.08Å; A440-N502 HydrophobicContact CB-CB 3.69Å; S498-N502 PolarHBondContact O-N 3.45Å; F499-N502 WeakPolarHBondContact O-CB 3.45Å; F499-N502 PolarHBondContact O-N 3.17Å; F499-N502 VanDerWaalsContact O-N 3.15Å; L500-N502 VanDerWaalsContact C-N 3.29Å; L500-N502 PolarHBondContact O-N 3.05Å; N502-S506 WeakPolarHBondContact O-CB 3.34Å; N502-S506 PolarHBondContact O-N 3.23Å; N502-S506 PolarHBondContact O-OG 3.3Å; N502-S506 VanDerWaalsContact O-OG 3.09Å
503	V	94.1	Very high	92.8	Very high	31 Å²	31	45.5 Å²	45.5	19%	0.188	23%	0.23	C	C	.	.	H	α-helix	trans	-60.7	-55.5	-177.9	178.8	0	0	0	0	110.5	V429 F499 L500 F505 S506 Y507	V429-V503 HydrophobicContact CG1-CG2 4.18Å; V429-V503 HydrophobicContact CG2-CG2 4.46Å; F499-V503 HydrophobicContact CE1-CG2 4.27Å; F499-V503 HydrophobicContact CE2-CG2 4.29Å; F499-V503 HydrophobicContact CZ-CG2 4.06Å; F499-V503 WeakPolarHBondContact O-CG2 3.21Å; F499-V503 PolarHBondContact O-N 2.9Å; F499-V503 VanDerWaalsContact O-N 3.15Å; L500-V503 PolarHBondContact O-N 3.35Å; V503-F505 PolarHBondContact O-N 3.38Å; V503-S506 PolarHBondContact O-N 3.44Å; V503-Y507 HydrophobicContact CG1-CD2 3.72Å; V503-Y507 HydrophobicContact CG1-CE2 3.83Å; V503-Y507 VanDerWaalsContact O-CD2 3.24Å; V503-Y507 WeakPolarHBondContact O-CD2 3.24Å; V503-Y507 PolarHBondContact O-N 3.01Å
504	V	94.8	Very high	92.3	Very high	86 Å²	86	48.9 Å²	48.9	52%	0.521	24%	0.243	S	C	.	.	H	α-helix	trans	-60.6	-48.6	-174.6	171.9	0	0	0	0	111.5	L500 Y507 L508	L500-V504 VanDerWaalsContact O-CB 3.32Å; L500-V504 WeakPolarHBondContact O-CB 3.35Å; L500-V504 VanDerWaalsContact O-CG2 3.26Å; L500-V504 WeakPolarHBondContact O-CG2 3.35Å; L500-V504 PolarHBondContact O-N 3.04Å; V504-Y507 PolarHBondContact O-N 3.01Å; V504-L508 WeakPolarHBondContact O-CB 3.46Å; V504-L508 PolarHBondContact O-N 3.22Å
505	F	94.3	Very high	91.8	Very high	78 Å²	78	51.5 Å²	51.5	34%	0.342	26%	0.261	S	S	.	.	H	α-helix	trans	-71.5	-31.2	-178.6	-80.6	-94.1	0	0	0	112.5	A439 F443 A501 V503 T509	A439-F505 HydrophobicContact CB-CB 3.85Å; A439-F505 HydrophobicContact CB-CD1 4.17Å; A439-F505 HydrophobicContact CB-CD2 3.74Å; A439-F505 HydrophobicContact CB-CE2 4.31Å; A439-F505 HydrophobicContact CB-CG 3.65Å; F443-F505 AromaticContact CE2-CE2 3.98Å; F443-F505 HydrophobicContact CE2-CE2 3.98Å; F443-F505 HydrophobicContact CE2-CZ 4.26Å; F443-F505 HydrophobicContact CZ-CE2 4.44Å; A501-F505 HydrophobicContact CB-CD2 4.44Å; A501-F505 WeakPolarHBondContact O-CB 3.44Å; A501-F505 WeakPolarHBondContact O-CD2 3.45Å; A501-F505 PolarHBondContact O-N 3Å; V503-F505 PolarHBondContact O-N 3.38Å; F505-T509 WeakPolarHBondContact O-CB 3.49Å; F505-T509 VanDerWaalsContact O-CG2 3.3Å; F505-T509 WeakPolarHBondContact O-CG2 3.26Å; F505-T509 PolarHBondContact O-N 2.89Å; F505-T509 PolarHBondContact O-OG1 3.41Å
506	S	92	Very high	91	Very high	0 Å²	0	53.3 Å²	53.3	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-65.7	-48.5	172.7	-74.7	0	0	0	0	112.6	N433 G436 N502 V503 L508 T509 K510	N433-S506 PolarHBondContact N-OG 3.2Å; N433-S506 PolarHBondContact ND2-O 2.93Å; N433-S506 VanDerWaalsContact ND2-O 3.11Å; N433-S506 PolarHBondContact O-OG 3.37Å; N433-S506 WeakPolarHBondContact OD1-CA 3.34Å; N433-S506 PolarHBondContact OD1-OG 2.92Å; G436-S506 WeakPolarHBondContact CA-OG 3.12Å; N502-S506 WeakPolarHBondContact O-CB 3.34Å; N502-S506 PolarHBondContact O-N 3.23Å; N502-S506 PolarHBondContact O-OG 3.3Å; N502-S506 VanDerWaalsContact O-OG 3.09Å; V503-S506 PolarHBondContact O-N 3.44Å; S506-L508 PolarHBondContact O-N 2.71Å; S506-T509 PolarHBondContact O-N 3.26Å; S506-T509 PolarHBondContact O-OG1 2.82Å; S506-K510 VanDerWaalsContact O-CB 3.31Å; S506-K510 WeakPolarHBondContact O-CB 3.47Å; S506-K510 PolarHBondContact O-N 3.47Å
507	Y	91.2	Very high	90.2	Very high	108 Å²	108	56.1 Å²	56.1	42%	0.424	29%	0.294	S	S	.	.	H	α-helix	trans	-66.5	-37.8	177.3	-81.7	-79	0	0	0	112.3	V429 K430 V503 V504 K510 Y511	V429-Y507 HydrophobicContact CG1-CE2 4.33Å; K430-Y507 VanDerWaalsContact O-CZ 3.24Å; K430-Y507 PolarHBondContact O-OH 2.85Å; V503-Y507 HydrophobicContact CG1-CD2 3.72Å; V503-Y507 HydrophobicContact CG1-CE2 3.83Å; V503-Y507 VanDerWaalsContact O-CD2 3.24Å; V503-Y507 WeakPolarHBondContact O-CD2 3.24Å; V503-Y507 PolarHBondContact O-N 3.01Å; V504-Y507 PolarHBondContact O-N 3.01Å; Y507-K510 PolarHBondContact O-N 3.43Å; Y507-Y511 VanDerWaalsContact O-CB 3.32Å; Y507-Y511 WeakPolarHBondContact O-CB 3.28Å; Y507-Y511 PolarHBondContact O-N 3.44Å
508	L	91.2	Very high	89.5	Confident	78 Å²	78	57.8 Å²	57.8	41%	0.408	30%	0.298	S	S	.	.	H	α-helix	trans	-63	-48.6	176.1	178	62	0	0	0	111.3	V504 S506 Y511 L512	V504-L508 WeakPolarHBondContact O-CB 3.46Å; V504-L508 PolarHBondContact O-N 3.22Å; S506-L508 PolarHBondContact O-N 2.71Å; L508-Y511 PolarHBondContact O-N 3.3Å; L508-L512 HydrophobicContact CD1-CD1 3.97Å; L508-L512 HydrophobicContact CD1-CG 4.1Å; L508-L512 HydrophobicContact CG-CD1 3.87Å; L508-L512 HydrophobicContact CG-CG 4.4Å; L508-L512 WeakPolarHBondContact O-CB 3.39Å; L508-L512 WeakPolarHBondContact O-CG 3.45Å; L508-L512 PolarHBondContact O-N 2.85Å
509	T	87.9	Confident	88.7	Confident	21 Å²	21	60.6 Å²	60.6	13%	0.129	32%	0.318	C	S	.	.	H	α-helix	trans	-65.5	-41.2	178.7	49.1	0	0	0	0	111.5	N433 Y435 F505 S506 Y511 L512 F513	N433-T509 PolarHBondContact ND2-OG1 3.31Å; N433-T509 PolarHBondContact OD1-OG1 3.46Å; Y435-T509 HydrophobicContact CD2-CG2 4.17Å; Y435-T509 HydrophobicContact CG-CG2 4.05Å; F505-T509 WeakPolarHBondContact O-CB 3.49Å; F505-T509 VanDerWaalsContact O-CG2 3.3Å; F505-T509 WeakPolarHBondContact O-CG2 3.26Å; F505-T509 PolarHBondContact O-N 2.89Å; F505-T509 PolarHBondContact O-OG1 3.41Å; S506-T509 PolarHBondContact O-N 3.26Å; S506-T509 PolarHBondContact O-OG1 2.82Å; T509-Y511 PolarHBondContact O-N 2.93Å; T509-L512 PolarHBondContact O-N 3.16Å; T509-F513 WeakPolarHBondContact O-CD2 3.41Å; T509-F513 PolarHBondContact O-N 3.46Å
510	K	85.6	Confident	87.7	Confident	38 Å²	38	63.6 Å²	63.6	17%	0.165	33%	0.333	C	S	.	.	H	α-helix	trans	-54.8	-52.6	172	-174.1	173.1	-178.6	173.7	0	111.3	S506 Y507 L512 F513 E514 V528 D538	S506-K510 VanDerWaalsContact O-CB 3.31Å; S506-K510 WeakPolarHBondContact O-CB 3.47Å; S506-K510 PolarHBondContact O-N 3.47Å; Y507-K510 PolarHBondContact O-N 3.43Å; K510-L512 PolarHBondContact O-N 3.43Å; K510-F513 PolarHBondContact O-N 2.71Å; K510-E514 WeakPolarHBondContact CE-OE1 3.4Å; K510-E514 HydrophobicContact CG-CG 4.33Å; K510-E514 IonicContact NZ-OE1 2.77Å; K510-E514 WeakPolarHBondContact O-CB 3.23Å; K510-E514 WeakPolarHBondContact O-CG 3.24Å; K510-E514 PolarHBondContact O-N 3.12Å; K510-V528 HydrophobicContact CG-CG1 4.49Å; K510-D538 IonicContact NZ-OD1 3.27Å
511	Y	87.1	Confident	86.6	Confident	142 Å²	142	68.2 Å²	68.2	56%	0.557	35%	0.349	S	S	*	.	H	α-helix	trans	-59.2	-44.9	177.7	176.4	-100.2	0	0	0	112.7	Y507 L508 T509 F513 E514 S515 M517	Y507-Y511 VanDerWaalsContact O-CB 3.32Å; Y507-Y511 WeakPolarHBondContact O-CB 3.28Å; Y507-Y511 PolarHBondContact O-N 3.44Å; L508-Y511 PolarHBondContact O-N 3.3Å; T509-Y511 PolarHBondContact O-N 2.93Å; Y511-F513 PolarHBondContact O-N 3Å; Y511-E514 PolarHBondContact O-N 3.27Å; Y511-S515 WeakPolarHBondContact O-CB 3.36Å; Y511-S515 PolarHBondContact O-N 3.36Å; Y511-S515 PolarHBondContact O-OG 3.17Å; Y511-M517 HydrophobicContact CE1-SD 4.11Å
512	L	87.3	Confident	85.7	Confident	38 Å²	38	75.4 Å²	75.4	20%	0.199	38%	0.375	C	S	.	.	H	α-helix	trans	-65	-38.4	-177.4	-73.4	170.9	0	0	0	113	L508 T509 K510 S515 M517 L518	L508-L512 HydrophobicContact CD1-CD1 3.97Å; L508-L512 HydrophobicContact CD1-CG 4.1Å; L508-L512 HydrophobicContact CG-CD1 3.87Å; L508-L512 HydrophobicContact CG-CG 4.4Å; L508-L512 WeakPolarHBondContact O-CB 3.39Å; L508-L512 WeakPolarHBondContact O-CG 3.45Å; L508-L512 PolarHBondContact O-N 2.85Å; T509-L512 PolarHBondContact O-N 3.16Å; K510-L512 PolarHBondContact O-N 3.43Å; L512-S515 PolarHBondContact O-OG 3.05Å; L512-M517 HydrophobicContact CD2-CB 4.07Å; L512-M517 HydrophobicContact CD2-CE 4.19Å; L512-M517 HydrophobicContact CD2-SD 4.03Å; L512-M517 PolarHBondContact O-N 3.21Å; L512-L518 HydrophobicContact CB-CB 4.44Å; L512-L518 HydrophobicContact CB-CD1 4.14Å; L512-L518 HydrophobicContact CD1-CD1 4.22Å; L512-L518 PolarHBondContact O-N 2.91Å
513	F	85.8	Confident	84.9	Confident	6 Å²	6	75.7 Å²	75.7	3%	0.026	38%	0.377	C	S	.	.	H	α-helix	trans	-76.5	-43.9	176	-75	-67.1	0	0	0	112	Y435 T509 K510 Y511 S515 G516 L518 D523 V528 V529	Y435-F513 HydrophobicContact CD2-CE2 4.48Å; Y435-F513 AromaticContact CE2-CE2 3.93Å; Y435-F513 HydrophobicContact CE2-CE2 3.93Å; Y435-F513 HydrophobicContact CE2-CZ 4.45Å; T509-F513 WeakPolarHBondContact O-CD2 3.41Å; T509-F513 PolarHBondContact O-N 3.46Å; K510-F513 PolarHBondContact O-N 2.71Å; Y511-F513 PolarHBondContact O-N 3Å; F513-S515 PolarHBondContact O-N 2.89Å; F513-G516 PolarHBondContact O-N 2.94Å; F513-L518 HydrophobicContact CD1-CB 3.85Å; F513-L518 HydrophobicContact CE1-CB 3.88Å; F513-L518 HydrophobicContact CE1-CD2 3.79Å; F513-L518 HydrophobicContact CE1-CG 4.47Å; F513-L518 HydrophobicContact CE2-CD2 4.37Å; F513-L518 HydrophobicContact CG-CB 4.47Å; F513-L518 HydrophobicContact CZ-CD2 3.7Å; F513-D523 HydrophobicContact CD1-CB 4.41Å; F513-D523 HydrophobicContact CE1-CB 3.79Å; F513-D523 HydrophobicContact CE2-CB 4.39Å; F513-D523 HydrophobicContact CZ-CB 3.79Å; F513-V528 HydrophobicContact CB-CB 4.36Å; F513-V528 HydrophobicContact CB-CG1 3.8Å; F513-V528 HydrophobicContact CD2-CB 3.84Å; F513-V528 HydrophobicContact CD2-CG1 4.07Å; F513-V528 HydrophobicContact CD2-CG2 3.88Å; F513-V528 HydrophobicContact CE2-CG2 4.35Å; F513-V528 HydrophobicContact CG-CB 4.34Å; F513-V528 HydrophobicContact CG-CG1 4.29Å; F513-V529 HydrophobicContact CB-CG2 4.02Å; F513-V529 HydrophobicContact CD1-CG2 3.98Å; F513-V529 HydrophobicContact CG-CG2 4.09Å
514	E	84.6	Confident	84.1	Confident	132 Å²	132	80.7 Å²	80.7	62%	0.617	40%	0.397	S	S	*	.	H	α-helix	trans	-68.7	-33.2	-179.1	-71.7	179.4	168.7	0	0	113.1	K510 Y511 G516	K510-E514 WeakPolarHBondContact CE-OE1 3.4Å; K510-E514 HydrophobicContact CG-CG 4.33Å; K510-E514 IonicContact NZ-OE1 2.77Å; K510-E514 WeakPolarHBondContact O-CB 3.23Å; K510-E514 WeakPolarHBondContact O-CG 3.24Å; K510-E514 PolarHBondContact O-N 3.12Å; Y511-E514 PolarHBondContact O-N 3.27Å; E514-G516 PolarHBondContact O-N 3.45Å
515	S	84	Confident	83.1	Confident	55 Å²	55	79.7 Å²	79.7	39%	0.385	39%	0.387	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.5	-7	175	61.4	0	0	0	0	113.8	Y511 L512 F513 M517	Y511-S515 WeakPolarHBondContact O-CB 3.36Å; Y511-S515 PolarHBondContact O-N 3.36Å; Y511-S515 PolarHBondContact O-OG 3.17Å; L512-S515 PolarHBondContact O-OG 3.05Å; F513-S515 PolarHBondContact O-N 2.89Å; S515-M517 PolarHBondContact O-N 3.37Å; S515-M517 WeakPolarHBondContact OG-CG 3.2Å
516	G	79.6	Confident	82	Confident	54 Å²	54	81.1 Å²	81.1	56%	0.557	40%	0.398	S	S	*	.	T	Hydrogen-bonded Turn	trans	71.9	8.5	-175.6	0	0	0	0	0	114.6	F513 E514 L518	F513-G516 PolarHBondContact O-N 2.94Å; E514-G516 PolarHBondContact O-N 3.45Å; G516-L518 VanDerWaalsContact C-N 3.32Å
517	M	79.9	Confident	81.1	Confident	130 Å²	130	81.3 Å²	81.3	64%	0.64	40%	0.4	S	S	*	.	S	Bend	trans	-66.2	-35.8	174.5	-70.9	-178.1	71.2	0	0	111.8	Y511 L512 S515	Y511-M517 HydrophobicContact CE1-SD 4.11Å; L512-M517 HydrophobicContact CD2-CB 4.07Å; L512-M517 HydrophobicContact CD2-CE 4.19Å; L512-M517 HydrophobicContact CD2-SD 4.03Å; L512-M517 PolarHBondContact O-N 3.21Å; S515-M517 PolarHBondContact O-N 3.37Å; S515-M517 WeakPolarHBondContact OG-CG 3.2Å
518	L	80.9	Confident	79.8	Confident	60 Å²	60	76.5 Å²	76.5	31%	0.314	38%	0.382	S	S	.	.	S	Bend	trans	-103	131.6	168.7	-111.4	87.3	0	0	0	110.5	L512 F513 G516	L512-L518 HydrophobicContact CB-CB 4.44Å; L512-L518 HydrophobicContact CB-CD1 4.14Å; L512-L518 HydrophobicContact CD1-CD1 4.22Å; L512-L518 PolarHBondContact O-N 2.91Å; F513-L518 HydrophobicContact CD1-CB 3.85Å; F513-L518 HydrophobicContact CE1-CB 3.88Å; F513-L518 HydrophobicContact CE1-CD2 3.79Å; F513-L518 HydrophobicContact CE1-CG 4.47Å; F513-L518 HydrophobicContact CE2-CD2 4.37Å; F513-L518 HydrophobicContact CG-CB 4.47Å; F513-L518 HydrophobicContact CZ-CD2 3.7Å; G516-L518 VanDerWaalsContact C-N 3.32Å
519	S	78.4	Confident	78.3	Confident	60 Å²	60	75.4 Å²	75.4	42%	0.42	38%	0.378	S	S	.	.			trans	-64.3	140.8	171.7	-173.9	0	0	0	0	110.7	K521 Y522	S519-K521 PolarHBondContact O-N 3.34Å; S519-Y522 PolarHBondContact O-N 2.99Å
520	H	75.7	Confident	77.3	Confident	118 Å²	118	75.9 Å²	75.9	55%	0.546	38%	0.382	S	S	.	.	G	3₁₀ helix	trans	-56.6	-23	177.4	-67	-149.8	0	0	0	112.8	Y522 D523 V529	H520-Y522 PolarHBondContact O-N 3.48Å; H520-D523 PolarHBondContact O-N 3.35Å; H520-D523 VanDerWaalsContact O-N 3.17Å; H520-V529 HydrophobicContact CB-CG1 4.04Å; H520-V529 HydrophobicContact CB-CG2 4.37Å; H520-V529 WeakPolarHBondContact ND1-CG1 3.3Å
521	K	72.8	Confident	76	Confident	189 Å²	189	81.8 Å²	81.8	82%	0.822	41%	0.408	S	S	*	.	G	3₁₀ helix	trans	-63.2	-20	175	-66.4	-175.9	178.9	-179.4	0	113.7	S519	S519-K521 PolarHBondContact O-N 3.34Å
522	Y	77.9	Confident	74.6	Confident	159 Å²	159	81.2 Å²	81.2	62%	0.624	41%	0.41	S	S	*	.	G	3₁₀ helix	trans	-91.1	-1	178.7	-63.3	-67.9	0	0	0	113.3	Y435 S519 H520 F524	Y435-Y522 PolarHBondContact OH-O 3.29Å; S519-Y522 PolarHBondContact O-N 2.99Å; H520-Y522 PolarHBondContact O-N 3.48Å; Y522-F524 WeakPolarHBondContact O-CD1 3.35Å; Y522-F524 PolarHBondContact O-N 3.13Å
523	D	77.3	Confident	73.3	Confident	7 Å²	7	80.5 Å²	80.5	4%	0.037	41%	0.408	C	S	.	.			trans	-79	61.3	171.3	-169.2	10	0	0	0	110.9	Y435 F513 H520 M525 D526 A527 V528 V529	Y435-D523 WeakPolarHBondContact CE2-OD1 2.94Å; Y435-D523 WeakPolarHBondContact OH-CA 3.41Å; Y435-D523 PolarHBondContact OH-OD1 2.71Å; F513-D523 HydrophobicContact CD1-CB 4.41Å; F513-D523 HydrophobicContact CE1-CB 3.79Å; F513-D523 HydrophobicContact CE2-CB 4.39Å; F513-D523 HydrophobicContact CZ-CB 3.79Å; H520-D523 PolarHBondContact O-N 3.35Å; H520-D523 VanDerWaalsContact O-N 3.17Å; D523-M525 PolarHBondContact O-N 3.01Å; D523-D526 PolarHBondContact O-N 3.37Å; D523-D526 PolarHBondContact OD1-N 3Å; D523-A527 PolarHBondContact OD1-N 3.5Å; D523-A527 PolarHBondContact OD2-N 3.29Å; D523-V528 PolarHBondContact OD2-N 2.98Å; D523-V529 HydrophobicContact CB-CB 4.36Å; D523-V529 HydrophobicContact CB-CG2 4.13Å; D523-V529 WeakPolarHBondContact OD2-CB 3.47Å; D523-V529 PolarHBondContact OD2-N 2.93Å
524	F	77.1	Confident	72	Confident	136 Å²	136	82 Å²	82	60%	0.596	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.8	-13.2	-175.9	69.4	-92	0	0	0	114.2	Y435 Y522	Y435-F524 HydrophobicContact CE1-CD1 4.25Å; Y435-F524 AromaticContact CE1-CE1 3.56Å; Y435-F524 HydrophobicContact CE1-CE1 3.56Å; Y435-F524 HydrophobicContact CE1-CE2 4.47Å; Y435-F524 AromaticContact CE1-CZ 3.69Å; Y435-F524 HydrophobicContact CE1-CZ 3.69Å; Y435-F524 WeakPolarHBondContact OH-CD1 3.46Å; Y435-F524 PolarHBondContact OH-N 2.91Å; Y522-F524 WeakPolarHBondContact O-CD1 3.35Å; Y522-F524 PolarHBondContact O-N 3.13Å
525	M	74.6	Confident	70.8	Confident	65 Å²	65	80.1 Å²	80.1	32%	0.32	41%	0.413	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97.1	2.6	174.4	-63.6	-150.4	178.5	0	0	112.4	T434 Y435 V438 D523 A527	T434-M525 HydrophobicContact CG2-CB 4.48Å; T434-M525 HydrophobicContact CG2-SD 3.51Å; T434-M525 VanDerWaalsContact CG2-SD 3.51Å; Y435-M525 HydrophobicContact CD1-SD 4.46Å; Y435-M525 HydrophobicContact CE1-CB 4.2Å; Y435-M525 HydrophobicContact CE1-CG 3.84Å; Y435-M525 HydrophobicContact CE1-SD 4.28Å; Y435-M525 HydrophobicContact CE2-CB 4.35Å; Y435-M525 PolarHBondContact OH-N 2.65Å; V438-M525 HydrophobicContact CG2-CE 4.11Å; V438-M525 HydrophobicContact CG2-SD 4.33Å; D523-M525 PolarHBondContact O-N 3.01Å; M525-A527 HydrophobicContact CB-CB 4.11Å; M525-A527 PolarHBondContact O-N 3.45Å; M525-A527 VanDerWaalsContact O-N 3.16Å
526	D	71.8	Confident	69.9	Low	107 Å²	107	79.5 Å²	79.5	57%	0.572	41%	0.405	S	S	*	.			trans	47.6	38.5	-173.7	-67	-48.4	0	0	0	111.7	D523 S533	D523-D526 PolarHBondContact O-N 3.37Å; D523-D526 PolarHBondContact OD1-N 3Å; D526-S533 WeakPolarHBondContact O-CB 3.49Å; D526-S533 PolarHBondContact O-OG 2.84Å
527	A	72.1	Confident	69	Low	5 Å²	5	77.3 Å²	77.3	4%	0.041	38%	0.381	C	S	.	.	S	Bend	trans	-94.2	-17.2	-165.6	0	0	0	0	0	113.3	N433 Y435 D523 M525	N433-A527 HydrophobicContact CB-CB 4.43Å; Y435-A527 HydrophobicContact CD2-CB 3.83Å; Y435-A527 HydrophobicContact CE2-CB 3.77Å; D523-A527 PolarHBondContact OD1-N 3.5Å; D523-A527 PolarHBondContact OD2-N 3.29Å; M525-A527 HydrophobicContact CB-CB 4.11Å; M525-A527 PolarHBondContact O-N 3.45Å; M525-A527 VanDerWaalsContact O-N 3.16Å
528	V	64.5	Low	68.1	Low	7 Å²	7	76.1 Å²	76.1	4%	0.042	38%	0.377	C	S	.	.	S	Bend	trans	-130.8	-46.8	-171.9	-177.9	0	0	0	0	112.4	Y435 K510 F513 D523	Y435-V528 HydrophobicContact CD2-CG2 4.41Å; K510-V528 HydrophobicContact CG-CG1 4.49Å; F513-V528 HydrophobicContact CB-CB 4.36Å; F513-V528 HydrophobicContact CB-CG1 3.8Å; F513-V528 HydrophobicContact CD2-CB 3.84Å; F513-V528 HydrophobicContact CD2-CG1 4.07Å; F513-V528 HydrophobicContact CD2-CG2 3.88Å; F513-V528 HydrophobicContact CE2-CG2 4.35Å; F513-V528 HydrophobicContact CG-CB 4.34Å; F513-V528 HydrophobicContact CG-CG1 4.29Å; D523-V528 PolarHBondContact OD2-N 2.98Å
529	V	59.3	Low	66.9	Low	54 Å²	54	79.8 Å²	79.8	33%	0.327	39%	0.39	S	S	.	.	S	Bend	trans	-86.7	-24.9	-170.6	175.6	0	0	0	0	112.2	F513 H520 D523 K531	F513-V529 HydrophobicContact CB-CG2 4.02Å; F513-V529 HydrophobicContact CD1-CG2 3.98Å; F513-V529 HydrophobicContact CG-CG2 4.09Å; H520-V529 HydrophobicContact CB-CG1 4.04Å; H520-V529 HydrophobicContact CB-CG2 4.37Å; H520-V529 WeakPolarHBondContact ND1-CG1 3.3Å; D523-V529 HydrophobicContact CB-CB 4.36Å; D523-V529 HydrophobicContact CB-CG2 4.13Å; D523-V529 WeakPolarHBondContact OD2-CB 3.47Å; D523-V529 PolarHBondContact OD2-N 2.93Å; V529-K531 PolarHBondContact O-N 3.47Å
530	S	67.2	Low	65.7	Low	32 Å²	32	77.4 Å²	77.4	22%	0.224	38%	0.375	C	S	.	.	S	Bend	trans	-62.4	130.8	178.8	123.7	0	0	0	0	110.3	H532 S533 A534	S530-H532 PolarHBondContact O-N 2.92Å; S530-H532 PolarHBondContact OG-N 3.4Å; S530-S533 WeakPolarHBondContact O-CA 3.26Å; S530-S533 PolarHBondContact O-N 3.36Å; S530-S533 WeakPolarHBondContact OG-CB 3.4Å; S530-S533 PolarHBondContact OG-N 2.86Å; S530-S533 PolarHBondContact OG-OG 2.98Å; S530-A534 PolarHBondContact O-N 3.37Å
531	K	57.4	Low	64.5	Low	162 Å²	162	72.5 Å²	72.5	70%	0.704	35%	0.353	S	S	*	.	H	α-helix	trans	-56	-37.3	179	-173.6	179.3	177.4	-176.3	0	111.9	V529 S533 E535	V529-K531 PolarHBondContact O-N 3.47Å; K531-S533 VanDerWaalsContact C-N 3.35Å; K531-E535 VanDerWaalsContact CE-OE1 3.25Å; K531-E535 WeakPolarHBondContact CE-OE1 3.25Å; K531-E535 WeakPolarHBondContact O-CG 3.39Å; K531-E535 PolarHBondContact O-N 3.35Å; K531-E535 VanDerWaalsContact O-N 3.12Å
532	H	58.4	Low	63.4	Low	129 Å²	129	66.8 Å²	66.8	60%	0.597	33%	0.331	S	S	*	.	H	α-helix	trans	-64	-41	175.7	-173.3	59.7	0	0	0	111.6	S530 I536	S530-H532 PolarHBondContact O-N 2.92Å; S530-H532 PolarHBondContact OG-N 3.4Å; H532-I536 VanDerWaalsContact CE1-CD1 3.46Å; H532-I536 WeakPolarHBondContact CE1-CD1 3.33Å; H532-I536 VanDerWaalsContact NE2-CD1 3.31Å; H532-I536 WeakPolarHBondContact NE2-CD1 3.36Å; H532-I536 WeakPolarHBondContact O-CB 3.26Å; H532-I536 WeakPolarHBondContact O-CD1 3.23Å; H532-I536 WeakPolarHBondContact O-CG1 3.25Å; H532-I536 PolarHBondContact O-N 3.21Å
533	S	60.3	Low	61.5	Low	23 Å²	23	62.8 Å²	62.8	16%	0.161	32%	0.323	C	S	.	.	H	α-helix	trans	-73.6	-38.7	-179.1	-53.9	0	0	0	0	112.1	D526 S530 K531 I536 M537	D526-S533 WeakPolarHBondContact O-CB 3.49Å; D526-S533 PolarHBondContact O-OG 2.84Å; S530-S533 WeakPolarHBondContact O-CA 3.26Å; S530-S533 PolarHBondContact O-N 3.36Å; S530-S533 WeakPolarHBondContact OG-CB 3.4Å; S530-S533 PolarHBondContact OG-N 2.86Å; S530-S533 PolarHBondContact OG-OG 2.98Å; K531-S533 VanDerWaalsContact C-N 3.35Å; S533-I536 PolarHBondContact O-N 2.89Å; S533-M537 WeakPolarHBondContact O-CB 3.31Å; S533-M537 VanDerWaalsContact O-CG 3.26Å; S533-M537 WeakPolarHBondContact O-CG 3.22Å; S533-M537 PolarHBondContact O-N 2.51Å
534	A	58	Low	59.5	Low	39 Å²	39	65.6 Å²	65.6	32%	0.322	34%	0.343	S	S	.	.	H	α-helix	trans	-61	-46.6	173.2	0	0	0	0	0	112	S530 I536 M537 D538	S530-A534 PolarHBondContact O-N 3.37Å; A534-I536 PolarHBondContact O-N 3.39Å; A534-M537 PolarHBondContact O-N 3.26Å; A534-D538 PolarHBondContact O-N 3.27Å
535	E	60.5	Low	57.4	Low	92 Å²	92	66.1 Å²	66.1	43%	0.43	35%	0.352	S	S	.	.	H	α-helix	trans	-63.9	-39	176.6	-74.4	175.8	-168.4	0	0	112.4	K531 K539	K531-E535 VanDerWaalsContact CE-OE1 3.25Å; K531-E535 WeakPolarHBondContact CE-OE1 3.25Å; K531-E535 WeakPolarHBondContact O-CG 3.39Å; K531-E535 PolarHBondContact O-N 3.35Å; K531-E535 VanDerWaalsContact O-N 3.12Å; E535-K539 WeakPolarHBondContact O-CB 3.45Å; E535-K539 VanDerWaalsContact O-CG 3.27Å; E535-K539 WeakPolarHBondContact O-CG 3.3Å; E535-K539 PolarHBondContact O-N 3.34Å
536	I	64.7	Low	55.4	Low	42 Å²	42	71.6 Å²	71.6	22%	0.215	38%	0.376	C	S	.	.	H	α-helix	trans	-69.9	-43.3	178.1	-71.3	169.6	0	0	0	111.3	L123 H532 S533 A534 D538 K539 A540	L123-I536 HydrophobicContact CD1-CG2 3.61Å; H532-I536 VanDerWaalsContact CE1-CD1 3.46Å; H532-I536 WeakPolarHBondContact CE1-CD1 3.33Å; H532-I536 VanDerWaalsContact NE2-CD1 3.31Å; H532-I536 WeakPolarHBondContact NE2-CD1 3.36Å; H532-I536 WeakPolarHBondContact O-CB 3.26Å; H532-I536 WeakPolarHBondContact O-CD1 3.23Å; H532-I536 WeakPolarHBondContact O-CG1 3.25Å; H532-I536 PolarHBondContact O-N 3.21Å; S533-I536 PolarHBondContact O-N 2.89Å; A534-I536 PolarHBondContact O-N 3.39Å; I536-D538 VanDerWaalsContact C-N 3.27Å; I536-D538 PolarHBondContact O-N 3.02Å; I536-K539 PolarHBondContact O-N 2.92Å; I536-A540 WeakPolarHBondContact O-CB 3.28Å; I536-A540 PolarHBondContact O-N 2.69Å
537	M	61.2	Low	53.7	Low	7 Å²	7	71.6 Å²	71.6	3%	0.034	38%	0.377	C	S	.	.	H	α-helix	trans	-60.3	-36.5	179	-78.6	-170.8	-58.5	0	0	112.9	L123 N433 S533 A534	L123-M537 HydrophobicContact CD1-CG 4.44Å; N433-M537 HydrophobicContact CB-SD 3.91Å; S533-M537 WeakPolarHBondContact O-CB 3.31Å; S533-M537 VanDerWaalsContact O-CG 3.26Å; S533-M537 WeakPolarHBondContact O-CG 3.22Å; S533-M537 PolarHBondContact O-N 2.51Å; A534-M537 PolarHBondContact O-N 3.26Å
538	D	59.4	Low	51.8	Low	105 Å²	105	78.7 Å²	78.7	56%	0.561	41%	0.414	S	S	*	.	H	α-helix	trans	-81.2	-27	-179.6	-75.4	-12.1	0	0	0	112.5	K510 A534 I536	K510-D538 IonicContact NZ-OD1 3.27Å; A534-D538 PolarHBondContact O-N 3.27Å; I536-D538 VanDerWaalsContact C-N 3.27Å; I536-D538 PolarHBondContact O-N 3.02Å
539	K	55.8	Low	50.5	Low	137 Å²	137	83.8 Å²	83.8	60%	0.596	44%	0.44	S	S	*	.	H	α-helix	trans	-92.8	-20.2	179.2	-70.6	-176.5	177.2	-165.3	0	114.9	E535 I536 T541	E535-K539 WeakPolarHBondContact O-CB 3.45Å; E535-K539 VanDerWaalsContact O-CG 3.27Å; E535-K539 WeakPolarHBondContact O-CG 3.3Å; E535-K539 PolarHBondContact O-N 3.34Å; I536-K539 PolarHBondContact O-N 2.92Å; K539-T541 PolarHBondContact O-N 2.84Å; K539-T541 VanDerWaalsContact O-N 3.14Å
540	A	53.5	Low	49.2	Very low	11 Å²	11	85.7 Å²	85.7	9%	0.091	45%	0.447	C	S	.	.	S	Bend	trans	-69.8	-12	-169.1	0	0	0	0	0	114.9	R111 L123 I536	R111-A540 PolarHBondContact NH1-O 3.34Å; R111-A540 PolarHBondContact NH2-O 3.4Å; L123-A540 HydrophobicContact CD1-CB 3.75Å; L123-A540 HydrophobicContact CD2-CB 4.08Å; L123-A540 HydrophobicContact CG-CB 4.41Å; I536-A540 WeakPolarHBondContact O-CB 3.28Å; I536-A540 PolarHBondContact O-N 2.69Å
541	T	51.1	Low	47.6	Very low	14 Å²	14	91.2 Å²	91.2	9%	0.086	47%	0.473	C	S	.	.			trans	-108.4	139.5	-167.9	-33.5	0	0	0	0	114.3	F428 V429 K430 K539 V543	F428-T541 VanDerWaalsContact O-CG2 3.3Å; F428-T541 WeakPolarHBondContact O-CG2 3.36Å; V429-T541 VanDerWaalsContact C-CG2 3.41Å; V429-T541 PolarHBondContact O-OG1 2.84Å; K430-T541 VanDerWaalsContact CA-OG1 3.24Å; K430-T541 WeakPolarHBondContact CA-OG1 3.46Å; K430-T541 HydrophobicContact CG-CG2 3.7Å; K430-T541 WeakPolarHBondContact CG-OG1 3.45Å; K539-T541 PolarHBondContact O-N 2.84Å; K539-T541 VanDerWaalsContact O-N 3.14Å; T541-V543 VanDerWaalsContact C-N 3.28Å; T541-V543 PolarHBondContact O-N 3.45Å
542	L	48.8	Very low	46.4	Very low	69 Å²	69	88.6 Å²	88.6	36%	0.361	48%	0.475	S	S	.	.	S	Bend	trans	-71.4	-5.3	-172	-68.6	163.5	0	0	0	116.7	P107 L427 F428	P107-L542 HydrophobicContact CB-CD1 3.36Å; P107-L542 HydrophobicContact CB-CD2 3.57Å; P107-L542 HydrophobicContact CB-CG 4.06Å; P107-L542 HydrophobicContact CG-CD1 3.7Å; L427-L542 HydrophobicContact CB-CD1 4.07Å; L427-L542 WeakPolarHBondContact O-CD1 3.36Å; L427-L542 WeakPolarHBondContact O-CG 3.26Å; L427-L542 PolarHBondContact O-N 3.06Å; F428-L542 HydrophobicContact CD1-CD1 3.89Å; F428-L542 HydrophobicContact CE1-CD1 3.57Å; F428-L542 HydrophobicContact CZ-CD1 4.29Å
543	V	39.2	Very low	45.3	Very low	75 Å²	75	89.1 Å²	89.1	46%	0.455	48%	0.478	S	S	.	.			trans	-114.9	83.8	-175.7	-171	0	0	0	0	110.8	K430 T541	K430-V543 WeakPolarHBondContact CE-O 2.97Å; K430-V543 PolarHBondContact NZ-O 2.92Å; T541-V543 VanDerWaalsContact C-N 3.28Å; T541-V543 PolarHBondContact O-N 3.45Å
544	S	34.1	Very low	44	Very low	66 Å²	66	92.2 Å²	92.2	46%	0.462	49%	0.491	S	S	.	.			trans	-94.4	110.9	144	61.2	0	0	0	0	106.8	H546	S544-H546 PolarHBondContact O-N 3.49Å
545	N	33.6	Very low	42.7	Very low	148 Å²	148	94.1 Å²	94.1	79%	0.791	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68	9.6	-177.7	-102.8	-12.3	0	0	0	113.7
546	H	33	Very low	41.1	Very low	179 Å²	179	95.5 Å²	95.5	83%	0.829	52%	0.524	S	S	*	.	T	Hydrogen-bonded Turn	trans	-141.6	-2.2	-168.6	-98.4	51.3	0	0	0	117	S544	S544-H546 PolarHBondContact O-N 3.49Å
547	D	35.4	Very low	39.8	Very low	108 Å²	108	97.3 Å²	97.3	58%	0.578	54%	0.536	S	S	*	.			trans	-115.7	117.6	-178.5	-66.1	-44.4	0	0	0	111.4	I549	D547-I549 PolarHBondContact O-N 3.03Å; D547-I549 VanDerWaalsContact O-N 3.15Å
548	N	31.7	Very low	38.4	Very low	154 Å²	154	107.5 Å²	107.5	82%	0.824	57%	0.574	S	S	*	*			trans	-40.3	123.5	151	-75.2	-39.7	0	0	0	107.5	I550	N548-I550 PolarHBondContact O-N 3.11Å
549	I	38.2	Very low	36.9	Very low	114 Å²	114	110.4 Å²	110.4	59%	0.585	59%	0.585	S	S	*	*			trans	-50.1	111.5	178.5	-56.7	166	0	0	0	107.5	D547 L551 M554	D547-I549 PolarHBondContact O-N 3.03Å; D547-I549 VanDerWaalsContact O-N 3.15Å; I549-L551 PolarHBondContact O-N 3.4Å; I549-M554 HydrophobicContact CB-CE 4.25Å; I549-M554 HydrophobicContact CG2-CE 3.25Å
550	I	31.3	Very low	35.8	Very low	94 Å²	94	107.6 Å²	107.6	48%	0.482	59%	0.587	S	S	.	*			trans	-67.9	103	-177.4	-59.8	177.1	0	0	0	106.4	N548 S552 E553	N548-I550 PolarHBondContact O-N 3.11Å; I550-S552 WeakPolarHBondContact CG2-OG 3.5Å; I550-S552 PolarHBondContact O-N 3.2Å; I550-E553 PolarHBondContact O-N 3Å; I550-E553 VanDerWaalsContact O-N 3.07Å
551	L	33.4	Very low	34.6	Very low	148 Å²	148	115 Å²	115	78%	0.775	62%	0.624	S	S	*	*	G	3₁₀ helix	trans	-54.9	-20.9	-176.4	-111.7	98.9	0	0	0	113.3	I549	I549-L551 PolarHBondContact O-N 3.4Å
552	S	33.4	Very low	33.6	Very low	106 Å²	106	116.2 Å²	116.2	74%	0.741	64%	0.64	S	S	*	*	G	3₁₀ helix	trans	-78.2	-12.5	-179.7	64.9	0	0	0	0	114.9	I550	I550-S552 WeakPolarHBondContact CG2-OG 3.5Å; I550-S552 PolarHBondContact O-N 3.2Å
553	E	34.8	Very low	32.9	Very low	140 Å²	140	117.9 Å²	117.9	65%	0.654	66%	0.663	S	S	*	*	G	3₁₀ helix	trans	-98.3	-4.1	176.5	-66.8	-163.1	154.3	0	0	113.3	I550 A555	I550-E553 PolarHBondContact O-N 3Å; I550-E553 VanDerWaalsContact O-N 3.07Å; E553-A555 PolarHBondContact O-N 2.97Å
554	M	33.8	Very low	32.6	Very low	88 Å²	88	119.6 Å²	119.6	43%	0.433	67%	0.674	S	S	.	*	S	Bend	trans	-74.3	124.5	168.4	-64.1	-169.4	-162.9	0	0	108.9	I549 P556	I549-M554 HydrophobicContact CB-CE 4.25Å; I549-M554 HydrophobicContact CG2-CE 3.25Å; M554-P556 VanDerWaalsContact O-N 3.17Å
555	A	29.7	Very low	32.5	Very low	79 Å²	79	123.5 Å²	123.5	65%	0.653	69%	0.689	S	S	*	*			trans	-53	125.6	161.5	0	0	0	0	0	107.3	E553 V557	E553-A555 PolarHBondContact O-N 2.97Å; A555-V557 PolarHBondContact O-N 3.16Å
556	P	27.4	Very low	32.2	Very low	122 Å²	122	120.1 Å²	120.1	79%	0.792	68%	0.682	S	S	*	*			trans	-61.3	108.2	-178.4	22.6	-31	0	0	0	107.7	M554 R558	M554-P556 VanDerWaalsContact O-N 3.17Å; P556-R558 VanDerWaalsContact C-N 3.3Å; P556-R558 PolarHBondContact O-N 2.95Å
557	V	36.9	Very low	32.1	Very low	79 Å²	79	114.6 Å²	114.6	48%	0.479	67%	0.673	S	S	.	*			trans	-63.8	101.9	164.5	177.7	0	0	0	0	104.3	A555 Q559	A555-V557 PolarHBondContact O-N 3.16Å; V557-Q559 VanDerWaalsContact C-N 3.28Å; V557-Q559 PolarHBondContact O-N 2.96Å
558	R	31.2	Very low	31.9	Very low	221 Å²	221	114.1 Å²	114.1	83%	0.834	67%	0.674	S	S	*	*			trans	-58.9	101.7	166	-88.9	-176.7	172.1	-178.8	-2.6	105.8	P556 A560	P556-R558 VanDerWaalsContact C-N 3.3Å; P556-R558 PolarHBondContact O-N 2.95Å; R558-A560 VanDerWaalsContact C-N 3.28Å; R558-A560 PolarHBondContact O-N 2.94Å
559	Q	27.8	Very low	32	Very low	166 Å²	166	115.6 Å²	115.6	78%	0.776	67%	0.674	S	S	*	*			trans	-58.2	104.5	155.8	-84.7	178.2	-23.2	0	0	105	V557 L561	V557-Q559 VanDerWaalsContact C-N 3.28Å; V557-Q559 PolarHBondContact O-N 2.96Å; Q559-L561 VanDerWaalsContact C-N 3.29Å; Q559-L561 PolarHBondContact O-N 3.43Å
560	A	33	Very low	31.7	Very low	78 Å²	78	115.6 Å²	115.6	65%	0.645	68%	0.679	S	S	*	*			trans	-59.1	108.8	155.3	0	0	0	0	0	104.2	R558 G562	R558-A560 VanDerWaalsContact C-N 3.28Å; R558-A560 PolarHBondContact O-N 2.94Å; A560-G562 PolarHBondContact O-N 3.37Å
561	L	29.3	Very low	31.6	Very low	167 Å²	167	117.3 Å²	117.3	87%	0.874	69%	0.689	S	S	*	*			trans	-64.1	80.7	167.8	-105.1	117.5	0	0	0	106.5	Q559 A563	Q559-L561 VanDerWaalsContact C-N 3.29Å; Q559-L561 PolarHBondContact O-N 3.43Å; L561-A563 PolarHBondContact O-N 2.82Å
562	G	29.1	Very low	31.6	Very low	40 Å²	40	115.3 Å²	115.3	41%	0.412	69%	0.694	S	S	.	*			trans	-67.4	99.6	166.4	0	0	0	0	0	106.6	A560 T564	A560-G562 PolarHBondContact O-N 3.37Å; G562-T564 VanDerWaalsContact C-N 3.27Å; G562-T564 PolarHBondContact O-N 3.28Å; G562-T564 PolarHBondContact O-OG1 3.49Å; G562-T564 VanDerWaalsContact O-OG1 3.12Å
563	A	34.2	Very low	31.7	Very low	104 Å²	104	118.6 Å²	118.6	86%	0.86	70%	0.697	S	S	*	*			trans	-56.6	92.8	172	0	0	0	0	0	109.1	L561	L561-A563 PolarHBondContact O-N 2.82Å
564	T	33.8	Very low	31.5	Very low	111 Å²	111	116 Å²	116	68%	0.681	70%	0.701	S	S	*	*			trans	-137.5	105	175.9	41	0	0	0	0	109.2	G562 A566	G562-T564 VanDerWaalsContact C-N 3.27Å; G562-T564 PolarHBondContact O-N 3.28Å; G562-T564 PolarHBondContact O-OG1 3.49Å; G562-T564 VanDerWaalsContact O-OG1 3.12Å; T564-A566 PolarHBondContact O-N 3.49Å
565	L	31.6	Very low	31.4	Very low	147 Å²	147	120.1 Å²	120.1	77%	0.77	72%	0.723	S	S	*	*	S	Bend	trans	51.7	0	146	-83.1	143.7	0	0	0	121.1
566	A	26.9	Very low	31.5	Very low	78 Å²	78	121.2 Å²	121.2	65%	0.645	73%	0.726	S	S	*	*	G	3₁₀ helix	trans	-82.5	-19.3	173.1	0	0	0	0	0	112.8	T564 T568	T564-A566 PolarHBondContact O-N 3.49Å; A566-T568 PolarHBondContact O-N 3.1Å
567	G	30.8	Very low	31.6	Very low	62 Å²	62	123.3 Å²	123.3	64%	0.639	73%	0.731	S	S	*	*	G	3₁₀ helix	trans	-74.5	-5.5	175.6	0	0	0	0	0	114.6
568	T	32.7	Very low	31.3	Very low	98 Å²	98	127.8 Å²	127.8	60%	0.601	75%	0.752	S	S	*	*	G	3₁₀ helix	trans	-93.7	-5	-176.4	-33	0	0	0	0	113.2	A566	A566-T568 PolarHBondContact O-N 3.1Å
569	F	32.6	Very low	31.2	Very low	186 Å²	186	120.5 Å²	120.5	82%	0.816	75%	0.746	S	S	*	*	S	Bend	trans	-123.5	10.5	-178.8	-72	-73.7	0	0	0	115
570	T	32.8	Very low	31.2	Very low	113 Å²	113	121.5 Å²	121.5	69%	0.693	75%	0.75	S	S	*	*			trans	-133.8	58	172.3	56.8	0	0	0	0	111
571	N	29.8	Very low	31	Very low	131 Å²	131	122.6 Å²	122.6	70%	0.701	75%	0.753	S	S	*	*			trans	-100.8	91.2	157.3	-96.7	-3.3	0	0	0	107.8	E573	N571-E573 PolarHBondContact O-N 2.8Å
572	A	33.2	Very low	30.9	Very low	106 Å²	106	120.2 Å²	120.2	88%	0.876	75%	0.75	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.5	23.3	170	0	0	0	0	0	112.3
573	E	35	Very low	31.3	Very low	174 Å²	174	123.6 Å²	123.6	81%	0.813	77%	0.765	S	S	*	*	T	Hydrogen-bonded Turn	trans	-113.2	11	178.1	-79.8	177.7	158.6	0	0	113.2	N571	N571-E573 PolarHBondContact O-N 2.8Å
574	A	31.3	Very low	31	Very low	87 Å²	87	127.2 Å²	127.2	72%	0.719	77%	0.765	S	S	*	*	S	Bend	trans	-95.2	24.3	177.4	0	0	0	0	0	114.2
575	L	30.6	Very low	30.7	Very low	173 Å²	173	127.7 Å²	127.7	91%	0.906	77%	0.772	S	S	*	*	S	Bend	trans	-141.2	57.7	175.9	-80	172.1	0	0	0	111.5
576	S	32.4	Very low	30.6	Very low	103 Å²	103	130.8 Å²	130.8	72%	0.72	78%	0.775	S	S	*	*			trans	-175.5	86.5	153.8	55	0	0	0	0	110.2
577	D	29.9	Very low	30.7	Very low	165 Å²	165	135.6 Å²	135.6	88%	0.882	78%	0.784	S	S	*	*			trans	-171.9	98.4	138.1	-119	-13.6	0	0	0	110.2
578	D	29.7	Very low	30.6	Very low	174 Å²	174	137.3 Å²	137.3	93%	0.93	79%	0.786	S	S	*	*			trans	-86.5	117.5	154.8	-87.7	-36.8	0	0	0	106.8
579	G	28.5	Very low	30.6	Very low	68 Å²	68	142 Å²	142	70%	0.701	80%	0.798	S	S	*	*			trans	174.8	63.4	178.2	0	0	0	0	0	117.1
580	E	27.6	Very low	30.8	Very low	186 Å²	186	144 Å²	144	87%	0.869	82%	0.817	S	S	*	*			trans	49	103.4	146	-68.4	-174.1	155.9	0	0	122.1
581	S	29	Very low	30.7	Very low	101 Å²	101	145.6 Å²	145.6	71%	0.706	82%	0.824	S	S	*	*				65.3	112	122.4	70.9	0	0	0	0	123.6
582	S	28.4	Very low	30.8	Very low	117 Å²	117	146.3 Å²	146.3	82%	0.818	83%	0.83	S	S	*	*				87.5	150.3	120	-71	0	0	0	0	122
583	P	36.4	Very low	30.6	Very low	112 Å²	112	148.6 Å²	148.6	73%	0.727	83%	0.827	S	S	*	*			trans	-128.4	-169.8	-134.7	35.3	-14.3	0	0	0	115.5
584	E	27.4	Very low	30.4	Very low	180 Å²	180	147.1 Å²	147.1	84%	0.841	83%	0.828	S	S	*	*			trans	102.1	116.6	159.4	-59.6	-173.2	161	0	0	118.6
585	S	27.9	Very low	30.3	Very low	120 Å²	120	150.8 Å²	150.8	84%	0.839	84%	0.835	S	S	*	*				174.3	145.3	99.2	52.5	0	0	0	0	113.3
586	Y	30.1	Very low	30.3	Very low	213 Å²	213	149.3 Å²	149.3	84%	0.835	83%	0.83	S	S	*	*			trans	-59	145.4	171.5	-85.1	-109.9	0	0	0	113.7
587	H	29.7	Very low	30.2	Very low	178 Å²	178	152.6 Å²	152.6	82%	0.824	84%	0.838	S	S	*	*				179.4	144.1	111.6	-105.4	-69.2	0	0	0	114.9
588	S	28.4	Very low	30.2	Very low	98 Å²	98	151.7 Å²	151.7	69%	0.685	84%	0.835	S	S	*	*			trans	-59	155	170.4	57.3	0	0	0	0	116.8
589	K	32.2	Very low	30.2	Very low	197 Å²	197	149.8 Å²	149.8	86%	0.857	83%	0.827	S	S	*	*			trans	-168.8	132.4	143.3	-93.4	170.9	-171.1	-179.5	0	105.2
590	N	37.1	Very low	30.4	Very low	228 Å²	228	157.3 Å²	157.3	100%	1.219	84%	0.838	S	S	*	*			cis	-148	0	10.9	-92.1	-20.5	0	0	0	108.6

Retrieved 590 of 590 residues in 2355.1 ms (Link to these results)

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