A0A087XLY6_POEFO Loading...

Neutral ceramidase

AlphaFold DB , UniProt , Accession A0A087XLY6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 737 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M46.4Very low61.8Low251 Ų251131.6 Ų131.6100%1.23671%0.714SS**  0105.50-108.5180-12000108.5
2A40.5Very low63.3Low97 Ų97124.7 Ų124.780%0.80269%0.688SS**  trans-151.477.2165.400000107.1R4A2-R4 PolarHBondContact O-N 3.06Å
3A45Very low64.6Low93 Ų93123.5 Ų123.577%0.76968%0.679SS**  trans-66.9104.1171.700000107.5R5A3-R5 VanDerWaalsContact C-N 3.31Å; A3-R5 PolarHBondContact O-N 3.18Å
4R53.2Low65.9Low248 Ų248121.8 Ų121.894%0.93667%0.667SS**  trans-6298.1167.3-80.3-177.2174.2-176.2-1.6107A2 C6A2-R4 PolarHBondContact O-N 3.06Å; R4-C6 PolarHBondContact O-N 2.9Å
5R58.6Low67.1Low238 Ų238118.7 Ų118.790%0.89865%0.653SS**  trans-65112.1172.9-71-177.6175.6-175.1-1.7107.3A3 S7A3-R5 VanDerWaalsContact C-N 3.31Å; A3-R5 PolarHBondContact O-N 3.18Å; R5-S7 PolarHBondContact O-N 3.12Å
6C57.4Low68.1Low79 Ų79118.3 Ų118.353%0.53465%0.649SS.*  trans-51126.2165.8-100.90000108.2R4 V11R4-C6 PolarHBondContact O-N 2.9Å; C6-V11 HydrophobicContact CB-CG2 4.13Å
7S76.1Confident69.1Low57 Ų57118.6 Ų118.640%0.39965%0.649SS.*  trans-65.7150.4176.469.90000109.6R5 L9 Q10 V11R5-S7 PolarHBondContact O-N 3.12Å; S7-L9 PolarHBondContact O-N 3.2Å; S7-Q10 WeakPolarHBondContact O-CB 3.35Å; S7-Q10 PolarHBondContact O-N 3.38Å; S7-Q10 PolarHBondContact OG-N 3.47Å; S7-V11 PolarHBondContact O-N 2.9Å
8A73.1Confident70Confident87 Ų87116.9 Ų116.972%0.71964%0.643SS**Hα-helixtrans-53.5-30.217700000112.3V11 A12A8-V11 PolarHBondContact O-N 2.89Å; A8-A12 WeakPolarHBondContact O-CB 3.35Å; A8-A12 PolarHBondContact O-N 2.8Å
9L75.6Confident70.9Confident124 Ų124116.1 Ų116.165%0.64964%0.636SS**Hα-helixtrans-67.1-39.5175.2-169.769.7000112.9S7 A12 L13S7-L9 PolarHBondContact O-N 3.2Å; L9-A12 PolarHBondContact O-N 2.73Å; L9-L13 HydrophobicContact CG-CD1 4.25Å; L9-L13 WeakPolarHBondContact O-CB 3.47Å; L9-L13 WeakPolarHBondContact O-CG 3.43Å; L9-L13 PolarHBondContact O-N 2.78Å
10Q75.9Confident71.5Confident99 Ų99115.3 Ų115.346%0.46363%0.629SS.*Hα-helixtrans-67.7-39.1175.8-78.2172.3-39.200111.6S7 L13 I14S7-Q10 WeakPolarHBondContact O-CB 3.35Å; S7-Q10 PolarHBondContact O-N 3.38Å; S7-Q10 PolarHBondContact OG-N 3.47Å; Q10-L13 PolarHBondContact O-N 2.74Å; Q10-I14 WeakPolarHBondContact O-CB 3.46Å; Q10-I14 WeakPolarHBondContact O-CD1 3.26Å; Q10-I14 WeakPolarHBondContact O-CG1 3.49Å; Q10-I14 PolarHBondContact O-N 2.78Å
11V78.3Confident72.1Confident75 Ų75113.6 Ų113.646%0.45562%0.622SS.*Hα-helixtrans-64.7-43.8174.3-179.30000110.4C6 S7 A8 L13 I14 V15C6-V11 HydrophobicContact CB-CG2 4.13Å; S7-V11 PolarHBondContact O-N 2.9Å; A8-V11 PolarHBondContact O-N 2.89Å; V11-L13 PolarHBondContact O-N 3.47Å; V11-I14 PolarHBondContact O-N 2.81Å; V11-V15 HydrophobicContact CG1-CG2 4.46Å; V11-V15 VanDerWaalsContact O-CG2 3.27Å; V11-V15 WeakPolarHBondContact O-CG2 3.46Å; V11-V15 PolarHBondContact O-N 2.78Å
12A79.8Confident73.9Confident48 Ų48104.4 Ų104.440%0.39759%0.586SS.*Hα-helixtrans-61.8-43.2177.300000112.3A8 L9 V15 L16A8-A12 WeakPolarHBondContact O-CB 3.35Å; A8-A12 PolarHBondContact O-N 2.8Å; L9-A12 PolarHBondContact O-N 2.73Å; A12-V15 PolarHBondContact O-N 3.25Å; A12-L16 WeakPolarHBondContact O-CB 3.34Å; A12-L16 PolarHBondContact O-N 3.5Å
13L80.3Confident76.2Confident109 Ų109103.3 Ų103.357%0.57157%0.569SS**Hα-helixtrans-65-39.8177-80.9163.4000112.6L9 Q10 V11 L16 L17L9-L13 HydrophobicContact CG-CD1 4.25Å; L9-L13 WeakPolarHBondContact O-CB 3.47Å; L9-L13 WeakPolarHBondContact O-CG 3.43Å; L9-L13 PolarHBondContact O-N 2.78Å; Q10-L13 PolarHBondContact O-N 2.74Å; V11-L13 PolarHBondContact O-N 3.47Å; L13-L16 PolarHBondContact O-N 2.96Å; L13-L17 WeakPolarHBondContact O-CB 3.49Å; L13-L17 PolarHBondContact O-N 2.9Å
14I82.7Confident77.9Confident100 Ų100101.7 Ų101.751%0.51355%0.552SS.*Hα-helixtrans-65.2-43.4175.7-69.2165.4000110.3Q10 V11 L16 L17 V18Q10-I14 WeakPolarHBondContact O-CB 3.46Å; Q10-I14 WeakPolarHBondContact O-CD1 3.26Å; Q10-I14 WeakPolarHBondContact O-CG1 3.49Å; Q10-I14 PolarHBondContact O-N 2.78Å; V11-I14 PolarHBondContact O-N 2.81Å; I14-L16 PolarHBondContact O-N 3.33Å; I14-L17 PolarHBondContact O-N 3.06Å; I14-V18 HydrophobicContact CG2-CG2 4.47Å; I14-V18 VanDerWaalsContact O-CG2 3.26Å; I14-V18 WeakPolarHBondContact O-CG2 3.43Å; I14-V18 PolarHBondContact O-N 2.94Å
15V83.9Confident79.3Confident76 Ų7694 Ų9446%0.46153%0.532SS..Hα-helixtrans-62.6-43.6176.71710000111V11 A12 L17 V18 I19V11-V15 HydrophobicContact CG1-CG2 4.46Å; V11-V15 VanDerWaalsContact O-CG2 3.27Å; V11-V15 WeakPolarHBondContact O-CG2 3.46Å; V11-V15 PolarHBondContact O-N 2.78Å; A12-V15 PolarHBondContact O-N 3.25Å; V15-L17 PolarHBondContact O-N 2.9Å; V15-V18 PolarHBondContact O-N 2.87Å; V15-I19 HydrophobicContact CG1-CD1 3.71Å; V15-I19 HydrophobicContact CG1-CG1 4.44Å; V15-I19 VanDerWaalsContact O-CG1 3.25Å; V15-I19 WeakPolarHBondContact O-CG1 3.27Å; V15-I19 PolarHBondContact O-N 2.87Å
16L83.1Confident80.3Confident112 Ų11285.1 Ų85.159%0.58651%0.51SS*.Hα-helixtrans-63.7-41.4177.1-120.8132.8000112.1A12 L13 I14 I19 M20A12-L16 WeakPolarHBondContact O-CB 3.34Å; A12-L16 PolarHBondContact O-N 3.5Å; L13-L16 PolarHBondContact O-N 2.96Å; I14-L16 PolarHBondContact O-N 3.33Å; L16-I19 PolarHBondContact O-N 3.35Å; L16-M20 VanDerWaalsContact O-CB 3.3Å; L16-M20 WeakPolarHBondContact O-CB 3.25Å; L16-M20 WeakPolarHBondContact O-CG 3.43Å; L16-M20 PolarHBondContact O-N 3.34Å
17L84.2Confident81.2Confident124 Ų12486 Ų8665%0.64951%0.508SS*.Hα-helixtrans-62.1-45.9176.5-167.982000110.9L13 I14 V15 M20 T21L13-L17 WeakPolarHBondContact O-CB 3.49Å; L13-L17 PolarHBondContact O-N 2.9Å; I14-L17 PolarHBondContact O-N 3.06Å; V15-L17 PolarHBondContact O-N 2.9Å; L17-M20 PolarHBondContact O-N 3.27Å; L17-T21 PolarHBondContact O-N 3.39Å; L17-T21 PolarHBondContact O-OG1 3.4Å
18V86.2Confident81.3Confident88 Ų8888 Ų8853%0.53351%0.514SS..Hα-helixtrans-63.9-42.2178.7171.50000111.4I14 V15 T21 A22I14-V18 HydrophobicContact CG2-CG2 4.47Å; I14-V18 VanDerWaalsContact O-CG2 3.26Å; I14-V18 WeakPolarHBondContact O-CG2 3.43Å; I14-V18 PolarHBondContact O-N 2.94Å; V15-V18 PolarHBondContact O-N 2.87Å; V18-T21 WeakPolarHBondContact CA-OG1 3.27Å; V18-T21 PolarHBondContact O-N 3.34Å; V18-T21 PolarHBondContact O-OG1 3.33Å; V18-A22 WeakPolarHBondContact O-CB 3.25Å; V18-A22 PolarHBondContact O-N 2.7Å
19I86.9Confident81.3Confident100 Ų10087.2 Ų87.251%0.51350%0.5SS..Hα-helixtrans-64.1-45.4175.8-68.5167.4000110.3V15 L16 T21 A22 V23V15-I19 HydrophobicContact CG1-CD1 3.71Å; V15-I19 HydrophobicContact CG1-CG1 4.44Å; V15-I19 VanDerWaalsContact O-CG1 3.25Å; V15-I19 WeakPolarHBondContact O-CG1 3.27Å; V15-I19 PolarHBondContact O-N 2.87Å; L16-I19 PolarHBondContact O-N 3.35Å; I19-T21 VanDerWaalsContact C-N 3.34Å; I19-T21 PolarHBondContact O-N 3.32Å; I19-A22 PolarHBondContact O-N 3.24Å; I19-V23 HydrophobicContact CG2-CG2 4.32Å; I19-V23 WeakPolarHBondContact O-CB 3.44Å; I19-V23 VanDerWaalsContact O-CG2 3.27Å; I19-V23 WeakPolarHBondContact O-CG2 3.47Å; I19-V23 PolarHBondContact O-N 2.65Å
20M82.3Confident81.2Confident101 Ų10186 Ų8650%0.49850%0.498SS..Hα-helixtrans-60.6-42.2176.8-85.4-99.632.700112.2L16 L17 V23 C24L16-M20 VanDerWaalsContact O-CB 3.3Å; L16-M20 WeakPolarHBondContact O-CB 3.25Å; L16-M20 WeakPolarHBondContact O-CG 3.43Å; L16-M20 PolarHBondContact O-N 3.34Å; L17-M20 PolarHBondContact O-N 3.27Å; M20-V23 PolarHBondContact O-N 3.17Å; M20-C24 WeakPolarHBondContact O-CB 3.24Å; M20-C24 PolarHBondContact O-N 2.82Å; M20-C24 PolarHBondContact O-SG 3.41Å; M20-C24 VanDerWaalsContact O-SG 3.4Å
21T84.9Confident80.8Confident80 Ų8087.9 Ų87.949%0.49151%0.51SS..Hα-helixtrans-66.7-42.6176.17.50000111.4L17 V18 I19 V23 C24 V25L17-T21 PolarHBondContact O-N 3.39Å; L17-T21 PolarHBondContact O-OG1 3.4Å; V18-T21 WeakPolarHBondContact CA-OG1 3.27Å; V18-T21 PolarHBondContact O-N 3.34Å; V18-T21 PolarHBondContact O-OG1 3.33Å; I19-T21 VanDerWaalsContact C-N 3.34Å; I19-T21 PolarHBondContact O-N 3.32Å; T21-V23 VanDerWaalsContact C-N 3.34Å; T21-V23 PolarHBondContact O-N 3.33Å; T21-C24 PolarHBondContact O-N 3.48Å; T21-V25 WeakPolarHBondContact O-CB 3.29Å; T21-V25 VanDerWaalsContact O-CG2 3.25Å; T21-V25 WeakPolarHBondContact O-CG2 3.29Å; T21-V25 PolarHBondContact O-N 2.83Å
22A84.9Confident79.9Confident58 Ų5889.2 Ų89.248%0.47952%0.519SS..Hα-helixtrans-62.6-40.4177.400000112.1V18 I19 A26V18-A22 WeakPolarHBondContact O-CB 3.25Å; V18-A22 PolarHBondContact O-N 2.7Å; I19-A22 PolarHBondContact O-N 3.24Å; A22-A26 VanDerWaalsContact O-CB 3.27Å; A22-A26 WeakPolarHBondContact O-CB 3.43Å; A22-A26 PolarHBondContact O-N 2.88Å
23V87.4Confident78.5Confident73 Ų7391.5 Ų91.544%0.44253%0.528SS..Hα-helixtrans-67.7-43.7176.41710000111.2I19 M20 T21 A26 L27I19-V23 HydrophobicContact CG2-CG2 4.32Å; I19-V23 WeakPolarHBondContact O-CB 3.44Å; I19-V23 VanDerWaalsContact O-CG2 3.27Å; I19-V23 WeakPolarHBondContact O-CG2 3.47Å; I19-V23 PolarHBondContact O-N 2.65Å; M20-V23 PolarHBondContact O-N 3.17Å; T21-V23 VanDerWaalsContact C-N 3.34Å; T21-V23 PolarHBondContact O-N 3.33Å; V23-A26 PolarHBondContact O-N 3.21Å; V23-L27 HydrophobicContact CG1-CD1 3.93Å; V23-L27 WeakPolarHBondContact O-CB 3.25Å; V23-L27 PolarHBondContact O-N 2.8Å
24C81.5Confident76.7Confident60 Ų6088.8 Ų88.841%0.40553%0.526SS..Hα-helixtrans-62.8-42.5175.3-76.90000112.1M20 T21 L27 I28M20-C24 WeakPolarHBondContact O-CB 3.24Å; M20-C24 PolarHBondContact O-N 2.82Å; M20-C24 PolarHBondContact O-SG 3.41Å; M20-C24 VanDerWaalsContact O-SG 3.4Å; T21-C24 PolarHBondContact O-N 3.48Å; C24-L27 PolarHBondContact O-N 2.83Å; C24-I28 WeakPolarHBondContact O-CB 3.35Å; C24-I28 VanDerWaalsContact O-CG1 3.24Å; C24-I28 WeakPolarHBondContact O-CG1 3.46Å; C24-I28 PolarHBondContact O-N 3.37Å
25V82.6Confident74.7Confident85 Ų8592.7 Ų92.752%0.51554%0.539SS..Hα-helixtrans-65.4-42.3176172.50000110.6T21 L27 I28 V29T21-V25 WeakPolarHBondContact O-CB 3.29Å; T21-V25 VanDerWaalsContact O-CG2 3.25Å; T21-V25 WeakPolarHBondContact O-CG2 3.29Å; T21-V25 PolarHBondContact O-N 2.83Å; V25-L27 PolarHBondContact O-N 3.04Å; V25-I28 PolarHBondContact O-N 3.18Å; V25-V29 HydrophobicContact CG1-CG2 4.38Å; V25-V29 WeakPolarHBondContact O-CB 3.23Å; V25-V29 VanDerWaalsContact O-CG2 3.25Å; V25-V29 WeakPolarHBondContact O-CG2 3.47Å; V25-V29 PolarHBondContact O-N 3.3Å
26A79.3Confident72.6Confident53 Ų5399 Ų9944%0.43856%0.56SS.*Hα-helixtrans-63.6-39.4175.800000112.3A22 V23 V29 V30A22-A26 VanDerWaalsContact O-CB 3.27Å; A22-A26 WeakPolarHBondContact O-CB 3.43Å; A22-A26 PolarHBondContact O-N 2.88Å; V23-A26 PolarHBondContact O-N 3.21Å; A26-V29 PolarHBondContact O-N 2.98Å; A26-V30 WeakPolarHBondContact O-CB 3.35Å; A26-V30 VanDerWaalsContact O-CG2 3.24Å; A26-V30 WeakPolarHBondContact O-CG2 3.3Å; A26-V30 PolarHBondContact O-N 2.7Å
27L76.4Confident70.5Confident96 Ų96100.4 Ų100.450%0.50357%0.568SS.*Hα-helixtrans-66.3-42174.2-95.1152.1000112.2V23 C24 V25 V29 V30 L31V23-L27 HydrophobicContact CG1-CD1 3.93Å; V23-L27 WeakPolarHBondContact O-CB 3.25Å; V23-L27 PolarHBondContact O-N 2.8Å; C24-L27 PolarHBondContact O-N 2.83Å; V25-L27 PolarHBondContact O-N 3.04Å; L27-V29 VanDerWaalsContact C-N 3.34Å; L27-V30 PolarHBondContact O-N 3.48Å; L27-L31 VanDerWaalsContact O-CB 3.27Å; L27-L31 WeakPolarHBondContact O-CB 3.05Å; L27-L31 WeakPolarHBondContact O-CD1 3.33Å; L27-L31 WeakPolarHBondContact O-CG 3.3Å; L27-L31 PolarHBondContact O-N 3.17Å
28I77.9Confident68.3Low100 Ų10098.9 Ų98.951%0.51357%0.574SS.*Hα-helixtrans-64.4-41.3174.6-69.3165.4000110.2C24 V25 L31 T32C24-I28 WeakPolarHBondContact O-CB 3.35Å; C24-I28 VanDerWaalsContact O-CG1 3.24Å; C24-I28 WeakPolarHBondContact O-CG1 3.46Å; C24-I28 PolarHBondContact O-N 3.37Å; V25-I28 PolarHBondContact O-N 3.18Å; I28-L31 PolarHBondContact O-N 3.37Å; I28-T32 HydrophobicContact CG2-CG2 4.19Å; I28-T32 VanDerWaalsContact O-CB 3.29Å; I28-T32 WeakPolarHBondContact O-CB 3.13Å; I28-T32 VanDerWaalsContact O-CG2 3.25Å; I28-T32 WeakPolarHBondContact O-CG2 3.36Å; I28-T32 PolarHBondContact O-N 3.5Å; I28-T32 PolarHBondContact O-OG1 2.82Å
29V74.4Confident66.2Low71 Ų7199 Ų9943%0.4358%0.584SS.*Hα-helixtrans-62.1-48.6173.9171.20000109.9V25 A26 L27 L31 T32 T33V25-V29 HydrophobicContact CG1-CG2 4.38Å; V25-V29 WeakPolarHBondContact O-CB 3.23Å; V25-V29 VanDerWaalsContact O-CG2 3.25Å; V25-V29 WeakPolarHBondContact O-CG2 3.47Å; V25-V29 PolarHBondContact O-N 3.3Å; A26-V29 PolarHBondContact O-N 2.98Å; L27-V29 VanDerWaalsContact C-N 3.34Å; V29-L31 VanDerWaalsContact C-N 3.31Å; V29-L31 PolarHBondContact O-N 3.1Å; V29-T32 WeakPolarHBondContact CA-OG1 3.37Å; V29-T32 CarbonylContact O-C 3.54Å; V29-T32 PolarHBondContact O-N 2.85Å; V29-T32 VanDerWaalsContact O-N 3.17Å; V29-T32 PolarHBondContact O-OG1 2.91Å; V29-T33 HydrophobicContact CG1-CG2 3.98Å; V29-T33 WeakPolarHBondContact O-CA 3.44Å; V29-T33 VanDerWaalsContact O-CB 3.29Å; V29-T33 WeakPolarHBondContact O-CB 3.45Å; V29-T33 WeakPolarHBondContact O-CG2 3.45Å; V29-T33 PolarHBondContact O-N 3.36Å; V29-T33 PolarHBondContact O-OG1 3.45Å
30V72.1Confident64.2Low98 Ų9899.2 Ų99.259%0.59459%0.592SS**Hα-helixtrans-63.1-35177.7170.60000112.7A26 L27 G34A26-V30 WeakPolarHBondContact O-CB 3.35Å; A26-V30 VanDerWaalsContact O-CG2 3.24Å; A26-V30 WeakPolarHBondContact O-CG2 3.3Å; A26-V30 PolarHBondContact O-N 2.7Å; L27-V30 PolarHBondContact O-N 3.48Å; V30-G34 PolarHBondContact O-N 3.32Å
31L67.6Low62.2Low138 Ų13897 Ų9772%0.72360%0.595SS**Hα-helixtrans-74.4-30.6175.8-73.1166.5000112.7L27 I28 V29L27-L31 VanDerWaalsContact O-CB 3.27Å; L27-L31 WeakPolarHBondContact O-CB 3.05Å; L27-L31 WeakPolarHBondContact O-CD1 3.33Å; L27-L31 WeakPolarHBondContact O-CG 3.3Å; L27-L31 PolarHBondContact O-N 3.17Å; I28-L31 PolarHBondContact O-N 3.37Å; V29-L31 VanDerWaalsContact C-N 3.31Å; V29-L31 PolarHBondContact O-N 3.1Å
32T59.9Low60Low104 Ų104100 Ų10064%0.63862%0.616SS**Hα-helixtrans-93.4-20.2179.555.20000113.5I28 V29I28-T32 HydrophobicContact CG2-CG2 4.19Å; I28-T32 VanDerWaalsContact O-CB 3.29Å; I28-T32 WeakPolarHBondContact O-CB 3.13Å; I28-T32 VanDerWaalsContact O-CG2 3.25Å; I28-T32 WeakPolarHBondContact O-CG2 3.36Å; I28-T32 PolarHBondContact O-N 3.5Å; I28-T32 PolarHBondContact O-OG1 2.82Å; V29-T32 WeakPolarHBondContact CA-OG1 3.37Å; V29-T32 CarbonylContact O-C 3.54Å; V29-T32 PolarHBondContact O-N 2.85Å; V29-T32 VanDerWaalsContact O-N 3.17Å; V29-T32 PolarHBondContact O-OG1 2.91Å
33T50.2Low58.8Low96 Ų96102.2 Ų102.259%0.58962%0.616SS**SBendtrans-106.613173.672.70000112.3V29 K35V29-T33 HydrophobicContact CG1-CG2 3.98Å; V29-T33 WeakPolarHBondContact O-CA 3.44Å; V29-T33 VanDerWaalsContact O-CB 3.29Å; V29-T33 WeakPolarHBondContact O-CB 3.45Å; V29-T33 WeakPolarHBondContact O-CG2 3.45Å; V29-T33 PolarHBondContact O-N 3.36Å; V29-T33 PolarHBondContact O-OG1 3.45Å; T33-K35 PolarHBondContact O-N 2.87Å
34G42.2Very low57.7Low51 Ų51100.5 Ų100.553%0.52661%0.614SS.*SBendtrans-50116.2164.800000108.2V30 K36V30-G34 PolarHBondContact O-N 3.32Å; G34-K36 PolarHBondContact O-N 2.93Å
35K40.7Very low57.8Low183 Ų183103.8 Ų103.880%0.79663%0.632SS**  trans-7.9104.4-177.9-77.4173.2172.1176.80113.2T33 D37T33-K35 PolarHBondContact O-N 2.87Å; K35-D37 PolarHBondContact O-N 3.31Å
36K40.2Very low58.3Low209 Ų209102 Ų10291%0.90962%0.622SS**  trans-59.598.3146.6-77.5-175.3176.3-177.80105G34 A38G34-K36 PolarHBondContact O-N 2.93Å; K36-A38 PolarHBondContact O-N 3.07Å
37D39.5Very low59.2Low140 Ų140100 Ų10075%0.74960%0.603SS**PPolyproline II helixtrans-48.9128.3167-75.6-38.9000107.1K35 A39K35-D37 PolarHBondContact O-N 3.31Å; D37-A39 PolarHBondContact O-N 3.29Å; D37-A39 VanDerWaalsContact O-N 3.12Å
38A38Very low60.2Low93 Ų9398.6 Ų98.677%0.76960%0.596SS**PPolyproline II helixtrans-50.8123.6178.800000108.2K36K36-A38 PolarHBondContact O-N 3.07Å
39A41.8Very low61.2Low89 Ų8993.8 Ų93.874%0.73657%0.571SS**PPolyproline II helixtrans-49.7128.1169.500000108.1D37 G41D37-A39 PolarHBondContact O-N 3.29Å; D37-A39 VanDerWaalsContact O-N 3.12Å; A39-G41 PolarHBondContact O-N 3.02Å
40P44.8Very low62.3Low105 Ų10590.4 Ų90.468%0.68255%0.551SS**PPolyproline II helixtrans-55.9139.3175.1-18.729.5000108.6
41G39.3Very low63.6Low56 Ų5686.4 Ų86.458%0.57753%0.526SS*.SBendtrans-54.1178.9177.900000113.5A39 Q43A39-G41 PolarHBondContact O-N 3.02Å; G41-Q43 PolarHBondContact O-N 3.19Å
42P39.4Very low65.1Low141 Ų14179.9 Ų79.992%0.91649%0.492SS*.SBendtrans-47.8106.1-159.122.1-33000111.9G44P42-G44 PolarHBondContact O-N 3.3Å
43Q59.3Low66.9Low105 Ų10576 Ų7649%0.49147%0.466SS..PPolyproline II helixtrans-65.1130.9-177.4-71179.2-17.900109G41 R185G41-Q43 PolarHBondContact O-N 3.19Å; Q43-R185 VanDerWaalsContact CB-NH2 3.28Å
44G65.7Low69.2Low38 Ų3871.6 Ų71.639%0.39244%0.439SS..PPolyproline II helixtrans-55157.117300000111.7P42 R185P42-G44 PolarHBondContact O-N 3.3Å; G44-R185 PolarHBondContact O-NH1 3.38Å
45T83.5Confident71.9Confident129 Ų12969.4 Ų69.479%0.79142%0.415SS*.PPolyproline II helixtrans-51.9126.4177.8-48.80000109.8
46P92.4Very high74.7Confident46 Ų4660.8 Ų60.830%0.29938%0.378SS..PPolyproline II helixtrans-63.5152.2177.628.2-34.7000110.4G184 L232P46-G184 WeakPolarHBondContact CB-O 3.45Å; P46-L232 HydrophobicContact CB-CD2 4Å; P46-L232 HydrophobicContact CG-CD2 4.34Å
47Y97.4Very high77.5Confident11 Ų1150.9 Ų50.94%0.04334%0.335CS..EExtended strand (participates in β ladder)trans-77.8160.7169.4-54.7-79.1000109.8I89 D90 D91 P183 G184 I186 V362 T363 G364 V366Y47-I89 HydrophobicContact CD1-CG2 3.88Å; Y47-I89 HydrophobicContact CG-CG2 3.87Å; Y47-D90 CarbonylContact C-O 3.24Å; Y47-D90 WeakPolarHBondContact CA-O 3.41Å; Y47-D90 WeakPolarHBondContact CB-O 3.36Å; Y47-D91 HydrophobicContact CD1-CB 4.03Å; Y47-D91 HydrophobicContact CE1-CB 4.18Å; Y47-P183 CarbonylContact O-C 3.51Å; Y47-P183 VanDerWaalsContact O-CA 3.3Å; Y47-P183 WeakPolarHBondContact O-CA 3.41Å; Y47-G184 PolarHBondContact N-O 3.39Å; Y47-G184 VanDerWaalsContact N-O 3.1Å; Y47-G184 PolarHBondContact O-N 2.89Å; Y47-I186 HydrophobicContact CD2-CD1 3.76Å; Y47-I186 HydrophobicContact CD2-CG1 3.99Å; Y47-I186 HydrophobicContact CE2-CD1 3.98Å; Y47-I186 HydrophobicContact CE2-CG1 4.27Å; Y47-I186 HydrophobicContact CG-CD1 4.38Å; Y47-V362 VanDerWaalsContact CE2-O 3.23Å; Y47-V362 WeakPolarHBondContact CE2-O 3.28Å; Y47-V362 PolarHBondContact OH-O 2.9Å; Y47-T363 WeakPolarHBondContact OH-CA 3.36Å; Y47-G364 WeakPolarHBondContact CE1-O 3.28Å; Y47-G364 PolarHBondContact OH-N 3.07Å; Y47-G364 PolarHBondContact OH-O 2.88Å; Y47-G364 VanDerWaalsContact OH-O 3.07Å; Y47-V366 HydrophobicContact CD1-CG2 4.43Å; Y47-V366 HydrophobicContact CE1-CG2 4.29Å
48L98Very high80.1Confident67 Ų6744.3 Ų44.335%0.35130%0.301SS..EExtended strand (participates in β ladder)trans-87.1124.9154.8-60.4172.2000108.3D90 M181 P183L48-D90 HydrophobicContact CB-CB 4.18Å; L48-D90 PolarHBondContact N-O 2.91Å; L48-D90 PolarHBondContact O-N 3.14Å; L48-M181 HydrophobicContact CB-CE 3.41Å; L48-M181 VanDerWaalsContact CB-CE 3.41Å; L48-M181 HydrophobicContact CD1-CE 3.98Å; L48-M181 HydrophobicContact CG-CE 4.35Å; L48-P183 HydrophobicContact CD2-CB 4.41Å; L48-P183 HydrophobicContact CD2-CG 3.8Å
49I98.5Very high82.9Confident0 Ų040.3 Ų40.30%027%0.267CS..EExtended strand (participates in β ladder)trans-122.5126.2-174.6-53.3171.6000108.9I88 M181 K182 I186 F229 I237I49-I88 CarbonylContact C-O 3.56Å; I49-I88 WeakPolarHBondContact CA-O 3.37Å; I49-M181 CarbonylContact O-C 3.35Å; I49-M181 WeakPolarHBondContact O-CA 3.37Å; I49-K182 PolarHBondContact N-O 2.92Å; I49-K182 PolarHBondContact O-N 3.45Å; I49-I186 HydrophobicContact CD1-CD1 4.24Å; I49-I186 HydrophobicContact CD1-CG1 3.63Å; I49-I186 HydrophobicContact CG1-CG1 4.47Å; I49-F229 HydrophobicContact CD1-CD1 4.26Å; I49-F229 HydrophobicContact CG2-CB 4.18Å; I49-F229 HydrophobicContact CG2-CD1 3.63Å; I49-F229 HydrophobicContact CG2-CE1 4.47Å; I49-F229 HydrophobicContact CG2-CG 4.24Å; I49-I237 HydrophobicContact CB-CD1 4.06Å; I49-I237 HydrophobicContact CG2-CD1 3.77Å
50G98.4Very high85.5Confident0 Ų036 Ų360%023%0.232CC..EExtended strand (participates in β ladder)trans-118.4138173.400000111F87 I88 A177G50-F87 WeakPolarHBondContact O-CA 3.3Å; G50-I88 PolarHBondContact N-O 3.04Å; G50-I88 PolarHBondContact O-N 3.16Å; G50-A177 WeakPolarHBondContact CA-O 3.45Å
51V98.8Very high87.9Confident13 Ų1331 Ų318%0.07920%0.199CC..EExtended strand (participates in β ladder)trans-128.4143174-61.90000110A86 F87 A177 I237 V285V51-A86 WeakPolarHBondContact CA-O 3.27Å; V51-F87 HydrophobicContact CG1-CD1 3.81Å; V51-F87 HydrophobicContact CG1-CE1 4.13Å; V51-A177 WeakPolarHBondContact O-CA 3.49Å; V51-I237 HydrophobicContact CG1-CD1 4.47Å; V51-I237 HydrophobicContact CG1-CG1 4.44Å; V51-I237 HydrophobicContact CG2-CB 4.5Å; V51-I237 WeakPolarHBondContact CG2-O 3.31Å; V51-V285 HydrophobicContact CB-CB 4.15Å; V51-V285 HydrophobicContact CB-CG2 4.08Å; V51-V285 HydrophobicContact CG2-CB 4.49Å; V51-V285 HydrophobicContact CG2-CG2 4.12Å
52G98.8Very high90.6Very high1 Ų130.2 Ų30.21%0.0118%0.18CC..EExtended strand (participates in β ladder)trans-154.8142.3-179.600000112.5R85 A86G52-R85 CarbonylContact O-C 3.4Å; G52-R85 WeakPolarHBondContact O-CA 3.47Å; G52-A86 PolarHBondContact N-O 3.17Å; G52-A86 PolarHBondContact O-N 3.36Å
53R98.9Very high93.3Very high24 Ų2423.6 Ų23.69%0.09114%0.137CC..EExtended strand (participates in β ladder)trans-124.1140.9173.9-178.4-17957.9-101.4-14.3108.8Y83 S84 R85 I176 E270 G280 Q281 G282 F284 V285R53-Y83 HydrophobicContact CG-CD1 3.78Å; R53-Y83 HydrophobicContact CG-CG 4.05Å; R53-S84 VanDerWaalsContact CA-O 3.3Å; R53-S84 WeakPolarHBondContact CA-O 3.39Å; R53-R85 HydrophobicContact CB-CG 4.44Å; R53-R85 HydrophobicContact CG-CG 4.13Å; R53-I176 WeakPolarHBondContact O-CD1 3.11Å; R53-E270 WeakPolarHBondContact CD-OE1 3.34Å; R53-E270 IonicContact CZ-OE1 2.9Å; R53-E270 IonicContact NH1-OE1 2.83Å; R53-E270 PolarHBondContact NH1-OE1 3.37Å; R53-E270 IonicContact NH1-OE2 3.43Å; R53-G280 PolarHBondContact NE-O 3.21Å; R53-G280 VanDerWaalsContact NH2-C 3.28Å; R53-G280 PolarHBondContact NH2-O 2.77Å; R53-Q281 PolarHBondContact NH2-O 3.34Å; R53-G282 PolarHBondContact NH2-O 2.78Å; R53-F284 PolarHBondContact NH1-O 3.09Å; R53-V285 HydrophobicContact CB-CG1 4.29Å; R53-V285 HydrophobicContact CB-CG2 4.1Å
54S98.8Very high95.1Very high3 Ų318.9 Ų18.92%0.02112%0.116CC..EExtended strand (participates in β ladder)trans-144.5143.7171.11780000109.8Y83 S84 G169 K172S54-Y83 WeakPolarHBondContact O-CA 3.45Å; S54-S84 PolarHBondContact N-O 3.24Å; S54-S84 PolarHBondContact O-N 3.32Å; S54-G169 VanDerWaalsContact CB-O 3.29Å; S54-G169 WeakPolarHBondContact CB-O 3.48Å; S54-K172 WeakPolarHBondContact OG-CD 3.29Å
55D98.7Very high96.6Very high4 Ų417.5 Ų17.52%0.02110%0.099CC..EExtended strand (participates in β ladder)trans-57.3138.4167.8-171.4-2.8000109.2T57 R81 L82 Y83 G169 R633D55-T57 WeakPolarHBondContact OD1-CB 3.31Å; D55-T57 PolarHBondContact OD1-N 3.43Å; D55-T57 PolarHBondContact OD1-OG1 2.88Å; D55-R81 IonicContact OD2-CZ 3.12Å; D55-R81 IonicContact OD2-NH1 2.7Å; D55-R81 PolarHBondContact OD2-NH1 3.31Å; D55-L82 VanDerWaalsContact OD1-O 3.08Å; D55-Y83 HydrophobicContact CB-CD1 4.38Å; D55-Y83 HydrophobicContact CB-CE1 4.23Å; D55-G169 VanDerWaalsContact O-CA 3.23Å; D55-G169 WeakPolarHBondContact O-CA 3.33Å; D55-R633 HydrophobicContact CB-CB 4.03Å; D55-R633 HydrophobicContact CB-CG 4.06Å; D55-R633 WeakPolarHBondContact O-CD 3.14Å; D55-R633 WeakPolarHBondContact OD2-CA 3.46Å
56C98.4Very high97.3Very high3 Ų311.8 Ų11.82%0.026%0.064CC..  trans-134.423175.170.20000111.8L82 L166C56-L82 PolarHBondContact N-O 3.18Å; C56-L82 PolarHBondContact SG-O 2.97Å; C56-L82 VanDerWaalsContact SG-O 3.42Å; C56-L166 HydrophobicContact CB-CD1 3.96Å
57T98.4Very high97.4Very high0 Ų010.6 Ų10.60%06%0.06CC..  trans-73.3124.7-176.7-520000111.6D55 I78 R81 L82 P165 V257D55-T57 WeakPolarHBondContact OD1-CB 3.31Å; D55-T57 PolarHBondContact OD1-N 3.43Å; D55-T57 PolarHBondContact OD1-OG1 2.88Å; T57-I78 HydrophobicContact CG2-CD1 4.49Å; T57-R81 WeakPolarHBondContact OG1-CD 3.25Å; T57-L82 PolarHBondContact OG1-N 3.43Å; T57-L82 PolarHBondContact OG1-O 3.24Å; T57-P165 WeakPolarHBondContact O-CB 3.37Å; T57-V257 HydrophobicContact CG2-CG1 4.05Å
58G95.8Very high97.3Very high3 Ų311.8 Ų11.83%0.0317%0.065CC..  trans-81.1177.5170.300000113.1
59P95Very high97Very high8 Ų811.3 Ų11.35%0.0527%0.07CC..  trans-60.9128.6-177.4-22.531.5000112.8A61 I63 A161 R627P59-A61 VanDerWaalsContact C-N 3.27Å; P59-A61 PolarHBondContact O-N 3.11Å; P59-A61 VanDerWaalsContact O-N 3.16Å; P59-I63 HydrophobicContact CB-CD1 3.76Å; P59-I63 HydrophobicContact CG-CD1 3.88Å; P59-A161 WeakPolarHBondContact CD-O 2.91Å; P59-A161 HydrophobicContact CG-CB 4.27Å; P59-R627 HydrophobicContact CB-CG 4.18Å
60P96.7Very high96.6Very high0 Ų012.5 Ų12.50%08%0.076CC..  trans-88.928.3-171.438.1-41.1000114.2A75 A76 G77 I78 V257 P626 F637 F663P60-A75 VanDerWaalsContact C-CB 3.47Å; P60-A75 CarbonylContact O-C 3.6Å; P60-A76 PolarHBondContact O-N 2.81Å; P60-G77 WeakPolarHBondContact CB-O 3.49Å; P60-G77 PolarHBondContact O-N 3.47Å; P60-I78 HydrophobicContact CB-CD1 3.95Å; P60-I78 HydrophobicContact CB-CG1 3.38Å; P60-I78 HydrophobicContact CG-CD1 3.88Å; P60-I78 HydrophobicContact CG-CG1 3.78Å; P60-V257 HydrophobicContact CB-CG2 3.94Å; P60-P626 HydrophobicContact CG-CB 3.83Å; P60-P626 HydrophobicContact CG-CG 4.46Å; P60-F637 HydrophobicContact CG-CD2 4.42Å; P60-F637 HydrophobicContact CG-CE2 3.65Å; P60-F637 HydrophobicContact CG-CZ 4.16Å; P60-F663 HydrophobicContact CG-CE1 4.36Å
61A96.5Very high96.1Very high0 Ų017.2 Ų17.20%011%0.107CC..EExtended strand (participates in β ladder)trans-141.7131-176.600000112.9P59 I63 A75 P626 R627 W665P59-A61 VanDerWaalsContact C-N 3.27Å; P59-A61 PolarHBondContact O-N 3.11Å; P59-A61 VanDerWaalsContact O-N 3.16Å; A61-I63 PolarHBondContact O-N 3.25Å; A61-A75 CarbonylContact C-O 3.59Å; A61-A75 WeakPolarHBondContact CA-O 3.35Å; A61-P626 HydrophobicContact CB-CB 3.85Å; A61-P626 HydrophobicContact CB-CG 3.8Å; A61-R627 HydrophobicContact CB-CG 4.31Å; A61-R627 VanDerWaalsContact O-CD 3.23Å; A61-R627 WeakPolarHBondContact O-CD 3.38Å; A61-R627 WeakPolarHBondContact O-CG 3.28Å; A61-W665 HydrophobicContact CB-CD2 3.94Å; A61-W665 HydrophobicContact CB-CE3 3.65Å; A61-W665 HydrophobicContact CB-CG 4.47Å; A61-W665 HydrophobicContact CB-CZ3 3.97Å
62E95.1Very high95.7Very high39 Ų3924 Ų2418%0.18214%0.138CC..EExtended strand (participates in β ladder)trans61-4.1175.4-52.8-178.1117.600116.6A75 N625 R627 W665 K667E62-A75 PolarHBondContact N-O 3.34Å; E62-N625 PolarHBondContact OE2-ND2 2.89Å; E62-R627 IonicContact OE2-NH1 3.95Å; E62-R627 PolarHBondContact OE2-NH1 3.47Å; E62-W665 HydrophobicContact CG-CH2 3.58Å; E62-W665 HydrophobicContact CG-CZ3 3.47Å; E62-W665 VanDerWaalsContact CG-CZ3 3.47Å; E62-K667 WeakPolarHBondContact OE1-CE 3.33Å; E62-K667 IonicContact OE1-NZ 3.51Å; E62-K667 PolarHBondContact OE1-NZ 3.32Å
63I95.6Very high95.5Very high1 Ų124.1 Ų24.11%0.00514%0.138CC..EExtended strand (participates in β ladder)trans-80.4132.4175.3-57.8-170.4000108.9P59 A61 T74 A75 P142 I159 A162 M586P59-I63 HydrophobicContact CB-CD1 3.76Å; P59-I63 HydrophobicContact CG-CD1 3.88Å; A61-I63 PolarHBondContact O-N 3.25Å; I63-T74 CarbonylContact O-C 3.53Å; I63-T74 WeakPolarHBondContact O-CA 3.37Å; I63-A75 WeakPolarHBondContact O-CB 3.42Å; I63-A75 PolarHBondContact O-N 2.76Å; I63-P142 HydrophobicContact CG2-CB 3.95Å; I63-I159 HydrophobicContact CD1-CG2 4.17Å; I63-I159 HydrophobicContact CG2-CD1 3.91Å; I63-A162 HydrophobicContact CD1-CB 4.16Å; I63-M586 HydrophobicContact CD1-CE 4.47Å; I63-M586 HydrophobicContact CG1-CE 4.02Å; I63-M586 HydrophobicContact CG1-SD 4.22Å
64P97Very high95.4Very high7 Ų723.9 Ų23.95%0.04514%0.14CC..EExtended strand (participates in β ladder)trans-54.9144.7172.5-24.635.1000111.7Q73 A143 K156P64-Q73 WeakPolarHBondContact CA-O 3.42Å; P64-A143 HydrophobicContact CB-CB 4.1Å; P64-A143 WeakPolarHBondContact O-CB 3.26Å; P64-A143 PolarHBondContact O-N 3.28Å; P64-K156 HydrophobicContact CG-CB 4.33Å; P64-K156 HydrophobicContact CG-CD 3.82Å; P64-K156 HydrophobicContact CG-CG 3.87Å
65L97.9Very high95.3Very high8 Ų823.8 Ų23.84%0.04214%0.139CC..EExtended strand (participates in β ladder)trans-85.7141.4169.4-60.1-177.6000109.6Q73 A75 G141 V257L65-Q73 HydrophobicContact CB-CG 4.08Å; L65-Q73 HydrophobicContact CD1-CG 4.05Å; L65-Q73 HydrophobicContact CG-CG 4.33Å; L65-Q73 PolarHBondContact N-O 3.38Å; L65-A75 HydrophobicContact CD2-CB 3.88Å; L65-G141 CarbonylContact C-O 3.56Å; L65-G141 WeakPolarHBondContact CA-O 3.43Å; L65-V257 HydrophobicContact CD2-CG2 4.45Å
66M97.9Very high95.3Very high10 Ų1024 Ų245%0.04914%0.142CC..EExtended strand (participates in β ladder)trans-86.2134.7-178.4-178.960.861.300110.6M105 H139 G141 A143 Y145 F146 S155M66-M105 HydrophobicContact CG-SD 3.88Å; M66-M105 HydrophobicContact SD-SD 4.36Å; M66-H139 CarbonylContact O-C 3.57Å; M66-H139 VanDerWaalsContact O-C 3.24Å; M66-H139 WeakPolarHBondContact O-CA 3.48Å; M66-G141 PolarHBondContact N-O 2.88Å; M66-A143 HydrophobicContact CB-CB 4.13Å; M66-A143 HydrophobicContact CE-CB 3.67Å; M66-Y145 HydrophobicContact CB-CE1 4.37Å; M66-Y145 HydrophobicContact CE-CE1 4.39Å; M66-Y145 HydrophobicContact CG-CE1 4.38Å; M66-Y145 WeakPolarHBondContact CG-OH 3.48Å; M66-F146 HydrophobicContact CE-CD2 3.68Å; M66-F146 HydrophobicContact CE-CE2 3.43Å; M66-F146 VanDerWaalsContact CE-CE2 3.43Å; M66-F146 HydrophobicContact CG-CE2 4.41Å; M66-F146 HydrophobicContact SD-CE2 3.88Å; M66-S155 WeakPolarHBondContact CE-OG 3.27Å
67G95.8Very high95.2Very high21 Ų2123.9 Ų23.922%0.21614%0.141CC..SBendtrans137.6-78.8175.600000112A69 H139G67-A69 PolarHBondContact O-N 2.9Å; G67-A69 VanDerWaalsContact O-N 3.14Å; G67-H139 VanDerWaalsContact C-ND1 3.33Å; G67-H139 VanDerWaalsContact CA-ND1 3.26Å; G67-H139 WeakPolarHBondContact CA-ND1 3.23Å
68Y95Very high95.3Very high36 Ų3624 Ų2414%0.14114%0.141CC..SBendtrans-69.4-10.8-173.8-66.5-68.5000115.7N70 H139 V248 M250 N251 Y252 D405Y68-N70 PolarHBondContact O-N 3.28Å; Y68-N70 VanDerWaalsContact O-N 3.08Å; Y68-H139 AromaticContact CD1-ND1 3.9Å; Y68-H139 HydrophobicContact CD2-CB 3.76Å; Y68-H139 AromaticContact CD2-ND1 4Å; Y68-H139 AromaticContact CE1-ND1 3.92Å; Y68-H139 HydrophobicContact CE2-CB 3.43Å; Y68-H139 VanDerWaalsContact CE2-CB 3.43Å; Y68-H139 AromaticContact CG-ND1 3.94Å; Y68-H139 AromaticContact CZ-ND1 4Å; Y68-H139 PolarHBondContact N-ND1 2.89Å; Y68-V248 HydrophobicContact CE1-CG1 4.48Å; Y68-V248 VanDerWaalsContact OH-CB 3.28Å; Y68-V248 WeakPolarHBondContact OH-CB 3.35Å; Y68-V248 PolarHBondContact OH-O 3.1Å; Y68-M250 WeakPolarHBondContact CE2-O 3.34Å; Y68-M250 PolarHBondContact OH-O 3.06Å; Y68-N251 WeakPolarHBondContact OH-CA 3.41Å; Y68-Y252 VanDerWaalsContact CG-CB 3.5Å; Y68-D405 VanDerWaalsContact CE1-O 3.29Å; Y68-D405 WeakPolarHBondContact CE1-O 3.34Å
69A90.6Very high95.4Very high56 Ų5623.8 Ų23.846%0.46314%0.139SC..  trans52.329.6-175.500000113.6G67 P71 T154G67-A69 PolarHBondContact O-N 2.9Å; G67-A69 VanDerWaalsContact O-N 3.14Å; A69-P71 WeakPolarHBondContact O-CD 3.5Å; A69-T154 HydrophobicContact CB-CG2 3.97Å
70N91Very high95.5Very high25 Ų2523.6 Ų23.613%0.13414%0.138CC..  trans-88.3118.5179.1-175.8-33.5000110.2Y68 Q72 Q73 Y252Y68-N70 PolarHBondContact O-N 3.28Å; Y68-N70 VanDerWaalsContact O-N 3.08Å; N70-Q72 PolarHBondContact O-N 3.46Å; N70-Q72 VanDerWaalsContact O-N 3.08Å; N70-Q72 WeakPolarHBondContact OD1-CB 3.47Å; N70-Q72 PolarHBondContact OD1-N 2.67Å; N70-Q73 HydrophobicContact CB-CB 3.99Å; N70-Q73 WeakPolarHBondContact O-CB 3.22Å; N70-Q73 PolarHBondContact O-N 2.77Å; N70-Y252 WeakPolarHBondContact ND2-CD2 3.35Å
71P86.9Confident95.6Very high100 Ų10023.8 Ų23.865%0.64914%0.139SC*.THydrogen-bonded Turntrans-60-22.1-178.1-24.634.4000115.2A69A69-P71 WeakPolarHBondContact O-CD 3.5Å
72Q90.4Very high95.7Very high155 Ų15524 Ų2472%0.72414%0.14SC*.THydrogen-bonded Turntrans-87.4-18.9-179.6-58.6172.86.400112N70 T74N70-Q72 PolarHBondContact O-N 3.46Å; N70-Q72 VanDerWaalsContact O-N 3.08Å; N70-Q72 WeakPolarHBondContact OD1-CB 3.47Å; N70-Q72 PolarHBondContact OD1-N 2.67Å; Q72-T74 PolarHBondContact O-N 3.45Å; Q72-T74 PolarHBondContact O-OG1 2.96Å
73Q95.2Very high95.9Very high3 Ų323.3 Ų23.31%0.01414%0.136CC..  trans-78.988-179.1-160.8-169.623.600110.5P64 L65 N70 Y252 N254P64-Q73 WeakPolarHBondContact CA-O 3.42Å; L65-Q73 HydrophobicContact CB-CG 4.08Å; L65-Q73 HydrophobicContact CD1-CG 4.05Å; L65-Q73 HydrophobicContact CG-CG 4.33Å; L65-Q73 PolarHBondContact N-O 3.38Å; N70-Q73 HydrophobicContact CB-CB 3.99Å; N70-Q73 WeakPolarHBondContact O-CB 3.22Å; N70-Q73 PolarHBondContact O-N 2.77Å; Q73-Y252 WeakPolarHBondContact CG-O 3.43Å; Q73-N254 WeakPolarHBondContact CG-O 3.26Å; Q73-N254 PolarHBondContact NE2-O 3.36Å
74T96Very high96.1Very high20 Ų2023.2 Ų23.212%0.12314%0.136CC..EExtended strand (participates in β ladder)trans-122.2137.4178.848.50000109.7I63 Q72 A76 R255I63-T74 CarbonylContact O-C 3.53Å; I63-T74 WeakPolarHBondContact O-CA 3.37Å; Q72-T74 PolarHBondContact O-N 3.45Å; Q72-T74 PolarHBondContact O-OG1 2.96Å; T74-A76 PolarHBondContact O-N 2.92Å; T74-R255 WeakPolarHBondContact O-CB 3.23Å; T74-R255 PolarHBondContact O-NE 3Å; T74-R255 PolarHBondContact O-NH2 3.47Å; T74-R255 PolarHBondContact OG1-NH2 3.17Å
75A97.6Very high96.2Very high0 Ų023.1 Ų23.10%013%0.134CC..EExtended strand (participates in β ladder)trans-52.7135.3179.200000110.8P60 A61 E62 I63 L65 R255 V257P60-A75 VanDerWaalsContact C-CB 3.47Å; P60-A75 CarbonylContact O-C 3.6Å; A61-A75 CarbonylContact C-O 3.59Å; A61-A75 WeakPolarHBondContact CA-O 3.35Å; E62-A75 PolarHBondContact N-O 3.34Å; I63-A75 WeakPolarHBondContact O-CB 3.42Å; I63-A75 PolarHBondContact O-N 2.76Å; L65-A75 HydrophobicContact CD2-CB 3.88Å; A75-R255 CarbonylContact C-O 3.55Å; A75-R255 VanDerWaalsContact CA-O 3.29Å; A75-R255 WeakPolarHBondContact CA-O 3.29Å; A75-V257 HydrophobicContact CB-CG2 4.36Å
76A97.7Very high96.2Very high10 Ų1022.8 Ų22.88%0.08313%0.132CC..EExtended strand (participates in β ladder)trans-149.135.4-178.200000109.9P60 T74 R255 W665P60-A76 PolarHBondContact O-N 2.81Å; T74-A76 PolarHBondContact O-N 2.92Å; A76-R255 HydrophobicContact CB-CB 3.96Å; A76-R255 PolarHBondContact N-O 3.38Å; A76-W665 PolarHBondContact O-N 3.12Å
77G98Very high96.3Very high0 Ų022.3 Ų22.30%013%0.13CC..EExtended strand (participates in β ladder)trans146.4178.9-174.600000115.2P60 M256 V257 F663P60-G77 WeakPolarHBondContact CB-O 3.49Å; P60-G77 PolarHBondContact O-N 3.47Å; G77-M256 WeakPolarHBondContact O-CA 3.4Å; G77-V257 PolarHBondContact O-N 2.98Å; G77-F663 CarbonylContact C-O 3.46Å; G77-F663 WeakPolarHBondContact CA-O 3.42Å
78I98.6Very high96.4Very high1 Ų121.3 Ų21.31%0.00512%0.12CC..EExtended strand (participates in β ladder)trans-126132.1174.2-59.7-176.1000108.1T57 P60 T80 V257 F637 D656 F663T57-I78 HydrophobicContact CG2-CD1 4.49Å; P60-I78 HydrophobicContact CB-CD1 3.95Å; P60-I78 HydrophobicContact CB-CG1 3.38Å; P60-I78 HydrophobicContact CG-CD1 3.88Å; P60-I78 HydrophobicContact CG-CG1 3.78Å; I78-T80 WeakPolarHBondContact CG2-O 3.3Å; I78-V257 HydrophobicContact CG1-CB 4.36Å; I78-F637 HydrophobicContact CD1-CD2 3.81Å; I78-F637 HydrophobicContact CD1-CE2 4.03Å; I78-D656 VanDerWaalsContact CG2-O 3.3Å; I78-D656 WeakPolarHBondContact CG2-O 3.42Å; I78-F663 HydrophobicContact CB-CB 4.44Å; I78-F663 HydrophobicContact CB-CD1 4.34Å; I78-F663 HydrophobicContact CG1-CD1 4.25Å; I78-F663 PolarHBondContact N-O 3.31Å; I78-F663 PolarHBondContact O-N 2.86Å
79H98.6Very high96.6Very high0 Ų019.8 Ų19.80%011%0.114CC..SBendtrans-99.2-48.3163.2177.6-147.3000110.3M256 V257 F337 W659H79-M256 HydrophobicContact CB-CB 4.01Å; H79-M256 HydrophobicContact CB-CE 3.94Å; H79-M256 HydrophobicContact CB-SD 4.18Å; H79-V257 PolarHBondContact N-O 2.83Å; H79-F337 AromaticContact CE1-CD1 3.59Å; H79-F337 AromaticContact ND1-CD1 3.67Å; H79-F337 AromaticContact ND1-CE1 3.76Å; H79-W659 AromaticContact CE1-CD2 3.62Å; H79-W659 AromaticContact CE1-CE2 3.68Å; H79-W659 AromaticContact CE1-CE3 3.39Å; H79-W659 AromaticContact CE1-CH2 3.38Å; H79-W659 WeakPolarHBondContact CE1-CH2 3.29Å; H79-W659 AromaticContact CE1-CZ2 3.57Å; H79-W659 AromaticContact CE1-CZ3 3.28Å; H79-W659 WeakPolarHBondContact CE1-CZ3 3.11Å; H79-W659 AromaticContact ND1-CZ3 3.97Å; H79-W659 AromaticContact NE2-CD2 3.62Å; H79-W659 AromaticContact NE2-CE2 3.87Å; H79-W659 AromaticContact NE2-CE3 3.69Å; H79-W659 PolarHBondContact NE2-O 2.99Å
80T98.3Very high97Very high4 Ų417.9 Ų17.93%0.02510%0.096CC..SBendtrans-139152.6169.363.40000110.5I78 V257 S259 W659I78-T80 WeakPolarHBondContact CG2-O 3.3Å; T80-V257 PolarHBondContact N-O 3.5Å; T80-S259 PolarHBondContact OG1-N 2.92Å; T80-S259 PolarHBondContact OG1-OG 3.49Å; T80-W659 HydrophobicContact CG2-CE3 3.68Å; T80-W659 HydrophobicContact CG2-CZ3 4.2Å
81R98.5Very high97.3Very high3 Ų318.7 Ų18.71%0.01110%0.1CC..  trans-67.3157.4168.7-70.1-69.7-177.9138.9-5.5111.1D55 T57 Y83 I632 Q635 D656 A657D55-R81 IonicContact OD2-CZ 3.12Å; D55-R81 IonicContact OD2-NH1 2.7Å; D55-R81 PolarHBondContact OD2-NH1 3.31Å; T57-R81 WeakPolarHBondContact OG1-CD 3.25Å; R81-Y83 HydrophobicContact CB-CD2 4.48Å; R81-Y83 HydrophobicContact CB-CE1 4.47Å; R81-Y83 HydrophobicContact CB-CE2 3.65Å; R81-Y83 WeakPolarHBondContact CB-OH 3.24Å; R81-I632 PolarHBondContact NH1-O 2.78Å; R81-Q635 PolarHBondContact NH2-O 2.73Å; R81-D656 IonicContact CZ-OD1 2.8Å; R81-D656 IonicContact CZ-OD2 3.92Å; R81-D656 IonicContact NE-OD1 3.04Å; R81-D656 PolarHBondContact NE-OD1 2.83Å; R81-D656 VanDerWaalsContact NE-OD1 3.09Å; R81-D656 IonicContact NE-OD2 2.79Å; R81-D656 PolarHBondContact NE-OD2 3.43Å; R81-D656 IonicContact NH2-OD1 2.79Å; R81-D656 IonicContact NH2-OD2 3.33Å; R81-D656 PolarHBondContact NH2-OD2 2.9Å; R81-A657 HydrophobicContact CB-CB 3.91Å; R81-A657 HydrophobicContact CG-CB 3.72Å
82L98.8Very high97.7Very high6 Ų617.3 Ų17.33%0.03110%0.104CC..  trans-104.4130.7176.2-53179.3000108.9D55 C56 T57 D102 V257 S258D55-L82 VanDerWaalsContact OD1-O 3.08Å; C56-L82 PolarHBondContact N-O 3.18Å; C56-L82 PolarHBondContact SG-O 2.97Å; C56-L82 VanDerWaalsContact SG-O 3.42Å; T57-L82 PolarHBondContact OG1-N 3.43Å; T57-L82 PolarHBondContact OG1-O 3.24Å; L82-D102 HydrophobicContact CB-CB 3.84Å; L82-D102 HydrophobicContact CD2-CB 3.96Å; L82-D102 HydrophobicContact CG-CB 4.47Å; L82-V257 HydrophobicContact CD1-CG1 3.73Å; L82-V257 HydrophobicContact CD2-CG1 3.97Å; L82-V257 HydrophobicContact CG-CG1 3.68Å; L82-S258 WeakPolarHBondContact CD2-O 3.42Å
83Y98.9Very high97.9Very high23 Ų2314.8 Ų14.89%0.0910%0.103CC..EExtended strand (participates in β ladder)trans-120.3145.3-178.5-61.1-85.6000112.6R53 S54 D55 R81 A101 D102 G280 A657R53-Y83 HydrophobicContact CG-CD1 3.78Å; R53-Y83 HydrophobicContact CG-CG 4.05Å; S54-Y83 WeakPolarHBondContact O-CA 3.45Å; D55-Y83 HydrophobicContact CB-CD1 4.38Å; D55-Y83 HydrophobicContact CB-CE1 4.23Å; R81-Y83 HydrophobicContact CB-CD2 4.48Å; R81-Y83 HydrophobicContact CB-CE1 4.47Å; R81-Y83 HydrophobicContact CB-CE2 3.65Å; R81-Y83 WeakPolarHBondContact CB-OH 3.24Å; Y83-A101 WeakPolarHBondContact O-CA 3.27Å; Y83-D102 PolarHBondContact N-OD2 3.05Å; Y83-D102 PolarHBondContact O-N 3.45Å; Y83-G280 VanDerWaalsContact OH-CA 3.3Å; Y83-G280 WeakPolarHBondContact OH-CA 3.49Å; Y83-A657 WeakPolarHBondContact OH-CB 3.48Å
84S98.9Very high98Very high0 Ų017.5 Ų17.50%011%0.114CC..EExtended strand (participates in β ladder)trans-92.4129.6160.3178.40000109.3R53 S54 V99 I170 S173R53-S84 VanDerWaalsContact CA-O 3.3Å; R53-S84 WeakPolarHBondContact CA-O 3.39Å; S54-S84 PolarHBondContact N-O 3.24Å; S54-S84 PolarHBondContact O-N 3.32Å; S84-V99 VanDerWaalsContact OG-CG1 3.22Å; S84-V99 WeakPolarHBondContact OG-CG1 3.39Å; S84-I170 WeakPolarHBondContact OG-CA 3.42Å; S84-S173 VanDerWaalsContact O-CB 3.23Å; S84-S173 WeakPolarHBondContact O-CB 3.4Å; S84-S173 PolarHBondContact OG-OG 2.91Å
85R98.9Very high98.1Very high5 Ų518.5 Ų18.52%0.01912%0.115CC..EExtended strand (participates in β ladder)trans-120.2115.6178.2-63.4-179.4178.983.6-2.4109.8G52 R53 F87 V99 T100 D102 E270 V285 A286G52-R85 CarbonylContact O-C 3.4Å; G52-R85 WeakPolarHBondContact O-CA 3.47Å; R53-R85 HydrophobicContact CB-CG 4.44Å; R53-R85 HydrophobicContact CG-CG 4.13Å; R85-F87 HydrophobicContact CB-CE2 4.07Å; R85-V99 WeakPolarHBondContact O-CA 3.19Å; R85-T100 HydrophobicContact CB-CG2 4.15Å; R85-T100 PolarHBondContact N-O 3.35Å; R85-T100 PolarHBondContact O-N 3.05Å; R85-D102 IonicContact CZ-OD2 3.25Å; R85-D102 IonicContact NH1-OD1 2.84Å; R85-D102 IonicContact NH1-OD2 2.7Å; R85-D102 PolarHBondContact NH1-OD2 3.32Å; R85-E270 IonicContact CZ-OE1 3.09Å; R85-E270 IonicContact CZ-OE2 3.57Å; R85-E270 IonicContact NE-OE1 3.25Å; R85-E270 PolarHBondContact NE-OE1 3.4Å; R85-E270 IonicContact NE-OE2 3.38Å; R85-E270 PolarHBondContact NE-OE2 3.2Å; R85-E270 IonicContact NH2-OE1 3.44Å; R85-E270 IonicContact NH2-OE2 2.8Å; R85-E270 PolarHBondContact NH2-OE2 2.72Å; R85-V285 HydrophobicContact CB-CG1 3.74Å; R85-V285 HydrophobicContact CG-CG1 3.79Å; R85-A286 WeakPolarHBondContact CD-O 3.16Å; R85-A286 PolarHBondContact NE-O 2.81Å; R85-A286 VanDerWaalsContact NE-O 3.12Å
86A98.9Very high98.1Very high0 Ų018.5 Ų18.50%012%0.115CC..EExtended strand (participates in β ladder)trans-110.4140.2-175.400000111.8V51 G52 V99 I174 A177V51-A86 WeakPolarHBondContact CA-O 3.27Å; G52-A86 PolarHBondContact N-O 3.17Å; G52-A86 PolarHBondContact O-N 3.36Å; A86-V99 HydrophobicContact CB-CG2 3.95Å; A86-I174 HydrophobicContact CB-CB 4.47Å; A86-I174 HydrophobicContact CB-CG1 3.86Å; A86-A177 HydrophobicContact CB-CB 4.15Å
87F98.9Very high98.2Very high0 Ų018 Ų180%011%0.111CC..EExtended strand (participates in β ladder)trans-129.6118.7178.8-57.8-96.1000108.4G50 V51 R85 I89 V97 F98 T100 F229 M239 I240 V285G50-F87 WeakPolarHBondContact O-CA 3.3Å; V51-F87 HydrophobicContact CG1-CD1 3.81Å; V51-F87 HydrophobicContact CG1-CE1 4.13Å; R85-F87 HydrophobicContact CB-CE2 4.07Å; F87-I89 HydrophobicContact CB-CD1 4.31Å; F87-V97 WeakPolarHBondContact O-CA 3.27Å; F87-F98 HydrophobicContact CD2-CD1 4.37Å; F87-F98 PolarHBondContact N-O 2.93Å; F87-F98 PolarHBondContact O-N 2.91Å; F87-T100 HydrophobicContact CE2-CG2 4.49Å; F87-F229 HydrophobicContact CD1-CD2 4.11Å; F87-F229 AromaticContact CD1-CE2 3.87Å; F87-F229 HydrophobicContact CD1-CE2 3.87Å; F87-F229 HydrophobicContact CD1-CZ 4.27Å; F87-F229 HydrophobicContact CE1-CD2 4.33Å; F87-F229 HydrophobicContact CE1-CE2 4.26Å; F87-M239 WeakPolarHBondContact CE1-O 3.49Å; F87-M239 WeakPolarHBondContact CZ-O 3.46Å; F87-I240 HydrophobicContact CB-CD1 3.88Å; F87-I240 HydrophobicContact CB-CG1 4.49Å; F87-I240 HydrophobicContact CD1-CD1 3.95Å; F87-I240 HydrophobicContact CD1-CG1 3.68Å; F87-I240 HydrophobicContact CD2-CD1 3.67Å; F87-I240 HydrophobicContact CD2-CG1 3.53Å; F87-I240 HydrophobicContact CE1-CD1 4.44Å; F87-I240 HydrophobicContact CE1-CG1 3.66Å; F87-I240 HydrophobicContact CE2-CD1 4.2Å; F87-I240 HydrophobicContact CE2-CG1 3.53Å; F87-I240 HydrophobicContact CG-CD1 3.55Å; F87-I240 HydrophobicContact CG-CG1 3.63Å; F87-I240 HydrophobicContact CZ-CG1 3.6Å; F87-V285 HydrophobicContact CE1-CG1 4.43Å; F87-V285 HydrophobicContact CZ-CG1 3.93Å
88I98.9Very high98.2Very high0 Ų018.2 Ų18.20%011%0.112CC..EExtended strand (participates in β ladder)trans-109.3127.9178.4-57.3-170000108.3I49 G50 R95 V96 V97 Y126 I174 A177 H178 M181I49-I88 CarbonylContact C-O 3.56Å; I49-I88 WeakPolarHBondContact CA-O 3.37Å; G50-I88 PolarHBondContact N-O 3.04Å; G50-I88 PolarHBondContact O-N 3.16Å; I88-R95 HydrophobicContact CG2-CG 3.61Å; I88-V96 WeakPolarHBondContact CA-O 3.47Å; I88-V97 HydrophobicContact CD1-CG2 4.26Å; I88-V97 HydrophobicContact CG1-CG1 4.23Å; I88-V97 HydrophobicContact CG1-CG2 4.04Å; I88-Y126 HydrophobicContact CD1-CE1 4.21Å; I88-Y126 WeakPolarHBondContact CD1-OH 3.31Å; I88-I174 HydrophobicContact CD1-CG2 4.2Å; I88-A177 HydrophobicContact CD1-CB 3.87Å; I88-A177 HydrophobicContact CG1-CB 3.78Å; I88-H178 HydrophobicContact CD1-CB 3.94Å; I88-M181 HydrophobicContact CG2-CG 4.43Å; I88-M181 HydrophobicContact CG2-SD 3.76Å
89I98.8Very high98.2Very high5 Ų518.2 Ų18.23%0.02611%0.112CC..EExtended strand (participates in β ladder)trans-127.1128.1176.6-54.386.9000108.3Y47 F87 R95 V96 I186 F229 V366 V472Y47-I89 HydrophobicContact CD1-CG2 3.88Å; Y47-I89 HydrophobicContact CG-CG2 3.87Å; F87-I89 HydrophobicContact CB-CD1 4.31Å; I89-R95 WeakPolarHBondContact O-CA 3.31Å; I89-V96 HydrophobicContact CB-CG2 4.14Å; I89-V96 HydrophobicContact CD1-CG2 4.48Å; I89-V96 PolarHBondContact N-O 3.39Å; I89-V96 PolarHBondContact O-N 2.93Å; I89-I186 HydrophobicContact CG1-CD1 3.93Å; I89-I186 HydrophobicContact CG2-CD1 3.8Å; I89-F229 HydrophobicContact CD1-CE1 4.06Å; I89-F229 HydrophobicContact CG1-CE1 3.93Å; I89-V366 HydrophobicContact CG2-CG2 4.1Å; I89-V472 HydrophobicContact CB-CG2 4.29Å; I89-V472 HydrophobicContact CD1-CG2 4.36Å; I89-V472 HydrophobicContact CG1-CG2 4.37Å; I89-V472 HydrophobicContact CG2-CG1 3.86Å; I89-V472 HydrophobicContact CG2-CG2 4.41Å
90D98.4Very high98.2Very high15 Ų1518.3 Ų18.38%0.0811%0.112CC..EExtended strand (participates in β ladder)trans-132125.1-178.5-171.8-25000109.8Y47 L48 G92 R94 R95 M181Y47-D90 CarbonylContact C-O 3.24Å; Y47-D90 WeakPolarHBondContact CA-O 3.41Å; Y47-D90 WeakPolarHBondContact CB-O 3.36Å; L48-D90 HydrophobicContact CB-CB 4.18Å; L48-D90 PolarHBondContact N-O 2.91Å; L48-D90 PolarHBondContact O-N 3.14Å; D90-G92 VanDerWaalsContact C-N 3.31Å; D90-G92 WeakPolarHBondContact OD1-CA 3.33Å; D90-G92 PolarHBondContact OD1-N 2.89Å; D90-R94 WeakPolarHBondContact CA-O 3.29Å; D90-R95 HydrophobicContact CB-CB 4.15Å; D90-R95 HydrophobicContact CB-CG 4.11Å; D90-R95 IonicContact OD2-CZ 2.91Å; D90-R95 IonicContact OD2-NE 3.65Å; D90-R95 PolarHBondContact OD2-NE 3.46Å; D90-R95 IonicContact OD2-NH2 3.87Å; D90-R95 PolarHBondContact OD2-NH2 3.01Å; D90-M181 HydrophobicContact CB-CE 3.82Å
91D97.1Very high98.3Very high43 Ų4318.2 Ų18.223%0.2311%0.112CC..  trans-90.29.2178.271.9-0.6000113.7Y47 S93 R94 V366Y47-D91 HydrophobicContact CD1-CB 4.03Å; Y47-D91 HydrophobicContact CE1-CB 4.18Å; D91-S93 VanDerWaalsContact C-N 3.29Å; D91-S93 WeakPolarHBondContact OD1-CA 3.32Å; D91-S93 WeakPolarHBondContact OD1-CB 3.16Å; D91-S93 PolarHBondContact OD1-N 3.35Å; D91-R94 PolarHBondContact N-O 3.47Å; D91-R94 VanDerWaalsContact N-O 3.14Å; D91-R94 PolarHBondContact OD1-N 2.92Å; D91-V366 HydrophobicContact CB-CB 4.16Å; D91-V366 HydrophobicContact CB-CG2 3.93Å; D91-V366 PolarHBondContact OD2-N 3.42Å
92G95.6Very high98.3Very high70 Ų7018.1 Ų18.172%0.72211%0.112SC*.SBendtrans88.6-11.9-174.400000113.7D90D90-G92 VanDerWaalsContact C-N 3.31Å; D90-G92 WeakPolarHBondContact OD1-CA 3.33Å; D90-G92 PolarHBondContact OD1-N 2.89Å
93S94.7Very high98.3Very high102 Ų10218.1 Ų18.171%0.71311%0.112SC*.SBendtrans-120.3-42176.7177.90000112.4D91D91-S93 VanDerWaalsContact C-N 3.29Å; D91-S93 WeakPolarHBondContact OD1-CA 3.32Å; D91-S93 WeakPolarHBondContact OD1-CB 3.16Å; D91-S93 PolarHBondContact OD1-N 3.35Å
94R96.9Very high98.3Very high61 Ų6117 Ų1723%0.2311%0.108CC..  trans-130.9140.9-176.9-61.3-169-163.1178.612.7109.4D90 D91 V366 R367 F368 D564D90-R94 WeakPolarHBondContact CA-O 3.29Å; D91-R94 PolarHBondContact N-O 3.47Å; D91-R94 VanDerWaalsContact N-O 3.14Å; D91-R94 PolarHBondContact OD1-N 2.92Å; R94-V366 HydrophobicContact CB-CB 4.3Å; R94-V366 HydrophobicContact CB-CG1 4.12Å; R94-V366 WeakPolarHBondContact CD-O 3.07Å; R94-R367 VanDerWaalsContact CZ-CD 3.49Å; R94-F368 HydrophobicContact CB-CE1 4.11Å; R94-F368 HydrophobicContact CG-CE1 4.47Å; R94-D564 IonicContact CZ-OD1 2.74Å; R94-D564 IonicContact NH1-OD1 3.47Å; R94-D564 IonicContact NH2-OD1 2.78Å; R94-D564 PolarHBondContact NH2-OD1 2.96Å; R94-D564 IonicContact NH2-OD2 2.64Å
95R98Very high98.2Very high41 Ų4117.4 Ų17.416%0.15511%0.11CC..EExtended strand (participates in β ladder)trans-119.9137.4178.7-175.8177.8-61.3-177.62110.4I88 I89 D90 Y126 N130 H178I88-R95 HydrophobicContact CG2-CG 3.61Å; I89-R95 WeakPolarHBondContact O-CA 3.31Å; D90-R95 HydrophobicContact CB-CB 4.15Å; D90-R95 HydrophobicContact CB-CG 4.11Å; D90-R95 IonicContact OD2-CZ 2.91Å; D90-R95 IonicContact OD2-NE 3.65Å; D90-R95 PolarHBondContact OD2-NE 3.46Å; D90-R95 IonicContact OD2-NH2 3.87Å; D90-R95 PolarHBondContact OD2-NH2 3.01Å; R95-Y126 HydrophobicContact CG-CE1 4.4Å; R95-Y126 PolarHBondContact NH1-OH 2.9Å; R95-N130 VanDerWaalsContact O-CB 3.3Å; R95-N130 WeakPolarHBondContact O-CB 3.23Å; R95-N130 PolarHBondContact O-ND2 3.34Å; R95-H178 PolarHBondContact NH1-CE1 2.81Å; R95-H178 PolarHBondContact NH1-ND1 3.24Å
96V98.8Very high98.2Very high0 Ų017.3 Ų17.30%011%0.11CC..EExtended strand (participates in β ladder)trans-123.3152.2171.1-68.60000110.8I88 I89 N130 V366 F368 I470 V472I88-V96 WeakPolarHBondContact CA-O 3.47Å; I89-V96 HydrophobicContact CB-CG2 4.14Å; I89-V96 HydrophobicContact CD1-CG2 4.48Å; I89-V96 PolarHBondContact N-O 3.39Å; I89-V96 PolarHBondContact O-N 2.93Å; V96-N130 CarbonylContact C-O 3.57Å; V96-N130 WeakPolarHBondContact CA-O 3.47Å; V96-N130 HydrophobicContact CG1-CB 4.38Å; V96-V366 HydrophobicContact CB-CG1 4.19Å; V96-V366 HydrophobicContact CG1-CG1 3.49Å; V96-V366 VanDerWaalsContact CG1-CG1 3.49Å; V96-V366 HydrophobicContact CG2-CG1 3.79Å; V96-F368 HydrophobicContact CG1-CB 4.2Å; V96-F368 HydrophobicContact CG1-CD1 3.64Å; V96-F368 HydrophobicContact CG1-CG 4.36Å; V96-I470 HydrophobicContact CB-CB 4.47Å; V96-I470 HydrophobicContact CB-CD1 4.35Å; V96-I470 HydrophobicContact CB-CG2 4.46Å; V96-I470 HydrophobicContact CG1-CB 4.09Å; V96-I470 HydrophobicContact CG1-CG2 4.05Å; V96-I470 HydrophobicContact CG2-CD1 4.47Å; V96-V472 HydrophobicContact CG2-CG2 3.94Å
97V98.9Very high98.2Very high0 Ų017.3 Ų17.30%011%0.11CC..EExtended strand (participates in β ladder)trans-123.6125.8173.6-173.30000108.5F87 I88 V99 Y126 N130 V131 V132 I174F87-V97 WeakPolarHBondContact O-CA 3.27Å; I88-V97 HydrophobicContact CD1-CG2 4.26Å; I88-V97 HydrophobicContact CG1-CG1 4.23Å; I88-V97 HydrophobicContact CG1-CG2 4.04Å; V97-V99 HydrophobicContact CG1-CG2 4.01Å; V97-Y126 HydrophobicContact CG2-CD1 3.42Å; V97-Y126 VanDerWaalsContact CG2-CD1 3.42Å; V97-Y126 HydrophobicContact CG2-CE1 3.43Å; V97-Y126 VanDerWaalsContact CG2-CE1 3.43Å; V97-Y126 HydrophobicContact CG2-CG 4.44Å; V97-N130 PolarHBondContact N-O 3.48Å; V97-V131 HydrophobicContact CB-CG1 4.39Å; V97-V131 HydrophobicContact CB-CG2 4.15Å; V97-V131 HydrophobicContact CG2-CG2 4.19Å; V97-V132 PolarHBondContact O-N 3.43Å; V97-I174 HydrophobicContact CG1-CD1 4.17Å; V97-I174 HydrophobicContact CG1-CG1 3.98Å; V97-I174 HydrophobicContact CG1-CG2 4.42Å
98F98.9Very high98.2Very high4 Ų417.4 Ų17.42%0.01811%0.11CC..EExtended strand (participates in β ladder)trans-113.8125.5167.1-178.8-98000109.2F87 V132 I240 W242 I470 V477 A514F87-F98 HydrophobicContact CD2-CD1 4.37Å; F87-F98 PolarHBondContact N-O 2.93Å; F87-F98 PolarHBondContact O-N 2.91Å; F98-V132 HydrophobicContact CD2-CB 3.93Å; F98-V132 HydrophobicContact CD2-CG1 3.69Å; F98-V132 HydrophobicContact CE2-CG1 3.79Å; F98-I240 HydrophobicContact CD1-CD1 3.72Å; F98-I240 HydrophobicContact CD1-CG1 4.44Å; F98-I240 HydrophobicContact CD1-CG2 4.43Å; F98-I240 HydrophobicContact CE1-CD1 4.33Å; F98-I240 HydrophobicContact CE1-CG2 3.97Å; F98-I240 HydrophobicContact CG-CD1 4.49Å; F98-W242 HydrophobicContact CD1-CZ2 4.42Å; F98-W242 AromaticContact CE1-CZ2 3.93Å; F98-W242 HydrophobicContact CE1-CZ2 3.93Å; F98-W242 HydrophobicContact CE2-CZ2 4.32Å; F98-W242 AromaticContact CZ-CZ2 3.89Å; F98-W242 HydrophobicContact CZ-CZ2 3.89Å; F98-W242 AromaticContact CZ-NE1 3.91Å; F98-I470 HydrophobicContact CB-CD1 4.18Å; F98-I470 HydrophobicContact CD2-CD1 4.47Å; F98-V477 HydrophobicContact CD2-CG1 4.09Å; F98-V477 HydrophobicContact CE2-CG1 3.87Å; F98-A514 HydrophobicContact CE2-CB 3.79Å; F98-A514 HydrophobicContact CZ-CB 4.17Å
99V98.9Very high98.2Very high1 Ų118.3 Ų18.31%0.00611%0.114CC..EExtended strand (participates in β ladder)trans-115.5130.8173.7-179.40000109.4S84 R85 A86 V97 A101 V132 L133 S134 I170 I174S84-V99 VanDerWaalsContact OG-CG1 3.22Å; S84-V99 WeakPolarHBondContact OG-CG1 3.39Å; R85-V99 WeakPolarHBondContact O-CA 3.19Å; A86-V99 HydrophobicContact CB-CG2 3.95Å; V97-V99 HydrophobicContact CG1-CG2 4.01Å; V99-A101 HydrophobicContact CG1-CB 4.49Å; V99-V132 PolarHBondContact N-O 2.83Å; V99-L133 HydrophobicContact CB-CD2 3.72Å; V99-L133 HydrophobicContact CG1-CD2 4.35Å; V99-L133 HydrophobicContact CG2-CD2 3.68Å; V99-S134 PolarHBondContact O-N 2.99Å; V99-I170 HydrophobicContact CG1-CG2 4.35Å; V99-I174 HydrophobicContact CG2-CD1 3.88Å; V99-I174 HydrophobicContact CG2-CG1 3.81Å
100T98.8Very high98.2Very high1 Ų118.1 Ų18.11%0.00611%0.112CC..EExtended strand (participates in β ladder)trans-113.2125.4161.3-171.60000108.7R85 F87 S134R85-T100 HydrophobicContact CB-CG2 4.15Å; R85-T100 PolarHBondContact N-O 3.35Å; R85-T100 PolarHBondContact O-N 3.05Å; F87-T100 HydrophobicContact CE2-CG2 4.49Å; T100-S134 CarbonylContact C-O 3.58Å; T100-S134 WeakPolarHBondContact CA-O 3.43Å
101A98.8Very high98.2Very high2 Ų217.4 Ų17.42%0.01711%0.109CC..EExtended strand (participates in β ladder)trans-122.4142.8-176.700000111.1Y83 V99 V103 S134 G135 T136Y83-A101 WeakPolarHBondContact O-CA 3.27Å; V99-A101 HydrophobicContact CG1-CB 4.49Å; A101-V103 HydrophobicContact CB-CG1 4.15Å; A101-V103 PolarHBondContact O-N 2.86Å; A101-S134 PolarHBondContact N-O 3.31Å; A101-G135 WeakPolarHBondContact O-CA 3.36Å; A101-T136 WeakPolarHBondContact O-CG2 2.95Å; A101-T136 PolarHBondContact O-N 2.79Å
102D98.8Very high98.3Very high1 Ų116.7 Ų16.71%0.00511%0.105CC..SBendtrans-71.472.6175.2-66.2-44.4000110.8L82 Y83 R85 T136L82-D102 HydrophobicContact CB-CB 3.84Å; L82-D102 HydrophobicContact CD2-CB 3.96Å; L82-D102 HydrophobicContact CG-CB 4.47Å; Y83-D102 PolarHBondContact N-OD2 3.05Å; Y83-D102 PolarHBondContact O-N 3.45Å; R85-D102 IonicContact CZ-OD2 3.25Å; R85-D102 IonicContact NH1-OD1 2.84Å; R85-D102 IonicContact NH1-OD2 2.7Å; R85-D102 PolarHBondContact NH1-OD2 3.32Å; D102-T136 WeakPolarHBondContact OD1-CG2 3.38Å
103V98.6Very high98.4Very high6 Ų614.9 Ų14.94%0.0368%0.078CC..SBendtrans-139.6152.6-178.867.70000109.4A101 M105 H137 Y145 L166A101-V103 HydrophobicContact CB-CG1 4.15Å; A101-V103 PolarHBondContact O-N 2.86Å; V103-M105 PolarHBondContact O-N 2.62Å; V103-H137 PolarHBondContact O-N 3.22Å; V103-Y145 HydrophobicContact CG2-CE1 3.95Å; V103-Y145 HydrophobicContact CG2-CE2 4.06Å; V103-Y145 VanDerWaalsContact CG2-OH 3.27Å; V103-Y145 WeakPolarHBondContact CG2-OH 3.3Å; V103-L166 HydrophobicContact CG2-CD2 4.18Å
104G98.4Very high98.6Very high0 Ų010 Ų100%04%0.044CC..SBendtrans-58.6-47.2176.900000112.1H137 T138 L516G104-H137 VanDerWaalsContact O-CA 3.28Å; G104-H137 WeakPolarHBondContact O-CA 3.43Å; G104-H137 PolarHBondContact O-ND1 3.5Å; G104-T138 WeakPolarHBondContact CA-O 3.47Å; G104-T138 PolarHBondContact N-O 2.85Å; G104-L516 WeakPolarHBondContact O-CD2 3.46Å
105M98.3Very high98.7Very high9 Ų98.1 Ų8.14%0.0444%0.038CC..  trans-157.5155.6177.8-41.972.716200109M66 V103 Y145 F146 L516 Y520M66-M105 HydrophobicContact CG-SD 3.88Å; M66-M105 HydrophobicContact SD-SD 4.36Å; V103-M105 PolarHBondContact O-N 2.62Å; M105-Y145 PolarHBondContact N-OH 2.94Å; M105-Y145 WeakPolarHBondContact O-CE2 3.4Å; M105-Y145 PolarHBondContact O-OH 2.89Å; M105-F146 HydrophobicContact CB-CZ 4.34Å; M105-F146 HydrophobicContact SD-CZ 4.36Å; M105-L516 HydrophobicContact CB-CD2 4.1Å; M105-L516 HydrophobicContact CG-CD2 3.78Å; M105-Y520 HydrophobicContact CB-CD1 4.48Å; M105-Y520 HydrophobicContact CB-CD2 3.81Å; M105-Y520 HydrophobicContact CB-CE2 4.48Å; M105-Y520 HydrophobicContact CB-CG 3.79Å; M105-Y520 HydrophobicContact CE-CD1 4.25Å; M105-Y520 HydrophobicContact CE-CE1 3.63Å; M105-Y520 HydrophobicContact CE-CE2 4.05Å; M105-Y520 HydrophobicContact CG-CD1 3.97Å; M105-Y520 HydrophobicContact CG-CD2 3.4Å; M105-Y520 VanDerWaalsContact CG-CD2 3.4Å; M105-Y520 HydrophobicContact CG-CE1 4.14Å; M105-Y520 HydrophobicContact CG-CE2 3.6Å; M105-Y520 HydrophobicContact CG-CG 3.58Å
106V98.8Very high98.7Very high2 Ų210.8 Ų10.81%0.0125%0.052CC..  trans-81.7124.5165.2-178.20000109.6L110 R111 L133 L516 N518 V519 Y520V106-L110 HydrophobicContact CG1-CD2 4.32Å; V106-R111 HydrophobicContact CG1-CB 4.26Å; V106-L133 HydrophobicContact CG1-CB 4Å; V106-L133 HydrophobicContact CG1-CD1 4.46Å; V106-L133 HydrophobicContact CG2-CB 4.04Å; V106-L133 WeakPolarHBondContact CG2-O 3.31Å; V106-L516 PolarHBondContact N-O 3.46Å; V106-N518 WeakPolarHBondContact CG1-O 3.28Å; V106-V519 CarbonylContact O-C 3.57Å; V106-V519 WeakPolarHBondContact O-CA 3.24Å; V106-Y520 PolarHBondContact O-N 2.88Å
107S98.7Very high98.7Very high1 Ų112 Ų121%0.0076%0.063CC..  trans-89.1154.8174.784.80000111.1R109 L110 R111 Y145 F146S107-R109 PolarHBondContact O-N 3.45Å; S107-R109 PolarHBondContact OG-N 3.44Å; S107-L110 PolarHBondContact O-N 2.93Å; S107-L110 VanDerWaalsContact O-N 3.15Å; S107-L110 WeakPolarHBondContact OG-CB 3.39Å; S107-L110 PolarHBondContact OG-N 2.88Å; S107-R111 PolarHBondContact O-N 2.86Å; S107-Y145 WeakPolarHBondContact CB-O 3.36Å; S107-Y145 PolarHBondContact OG-O 3.49Å; S107-F146 VanDerWaalsContact CB-CD1 3.44Å
108Q98.8Very high98.7Very high2 Ų212 Ų121%0.0096%0.063CC..Hα-helixtrans-58.5-37.6176.2-16764.3-55.200111.6R111 L112 Y148 D466 V519 P575Q108-R111 PolarHBondContact O-N 2.81Å; Q108-L112 HydrophobicContact CG-CD1 4.12Å; Q108-L112 WeakPolarHBondContact O-CB 3.35Å; Q108-L112 WeakPolarHBondContact O-CG 3.09Å; Q108-L112 PolarHBondContact O-N 2.83Å; Q108-Y148 HydrophobicContact CB-CE2 3.99Å; Q108-D466 PolarHBondContact NE2-OD2 3.03Å; Q108-D466 PolarHBondContact OE1-OD2 3.4Å; Q108-D466 VanDerWaalsContact OE1-OD2 3.1Å; Q108-V519 HydrophobicContact CB-CB 4.05Å; Q108-V519 HydrophobicContact CB-CG2 3.73Å; Q108-V519 HydrophobicContact CG-CG2 4.38Å; Q108-P575 HydrophobicContact CG-CB 3.97Å; Q108-P575 HydrophobicContact CG-CG 4.39Å; Q108-P575 VanDerWaalsContact NE2-CB 3.33Å
109R98.4Very high98.7Very high19 Ų1917.5 Ų17.57%0.0729%0.086CC..Hα-helixtrans-63.6-48.1176.9-170.7-179.1179.381.15.6111.8S107 R111 L112 E113 Q147 Y158 F577 F578S107-R109 PolarHBondContact O-N 3.45Å; S107-R109 PolarHBondContact OG-N 3.44Å; R109-R111 VanDerWaalsContact C-N 3.31Å; R109-R111 PolarHBondContact O-N 3.02Å; R109-L112 PolarHBondContact O-N 3.41Å; R109-E113 HydrophobicContact CG-CG 4.39Å; R109-E113 IonicContact CZ-OE1 3.39Å; R109-E113 IonicContact NE-OE1 3.27Å; R109-E113 PolarHBondContact NE-OE1 2.94Å; R109-E113 IonicContact NH2-OE1 2.71Å; R109-E113 PolarHBondContact NH2-OE1 2.87Å; R109-E113 WeakPolarHBondContact O-CG 3.31Å; R109-E113 PolarHBondContact O-N 2.9Å; R109-Q147 HydrophobicContact CB-CB 3.9Å; R109-Q147 HydrophobicContact CB-CG 4.02Å; R109-Q147 HydrophobicContact CG-CB 4.3Å; R109-Y158 VanDerWaalsContact NE-CZ 3.34Å; R109-F577 HydrophobicContact CG-CE2 4.19Å; R109-F578 PolarHBondContact NH1-O 3.43Å
110L98.8Very high98.7Very high0 Ų024.4 Ų24.40%012%0.118CC..Hα-helixtrans-57.7-46.5178.9175.360.4000110.8V106 S107 L112 E113 V114 Y145 L166 V167 I170V106-L110 HydrophobicContact CG1-CD2 4.32Å; S107-L110 PolarHBondContact O-N 2.93Å; S107-L110 VanDerWaalsContact O-N 3.15Å; S107-L110 WeakPolarHBondContact OG-CB 3.39Å; S107-L110 PolarHBondContact OG-N 2.88Å; L110-L112 PolarHBondContact O-N 3.5Å; L110-E113 PolarHBondContact O-N 3.37Å; L110-V114 HydrophobicContact CD1-CG2 4.18Å; L110-V114 WeakPolarHBondContact O-CB 3.48Å; L110-V114 VanDerWaalsContact O-CG2 3.32Å; L110-V114 WeakPolarHBondContact O-CG2 3.36Å; L110-V114 PolarHBondContact O-N 3.45Å; L110-Y145 HydrophobicContact CD2-CD2 4.43Å; L110-L166 HydrophobicContact CD1-CD2 4Å; L110-L166 HydrophobicContact CD1-CG 3.85Å; L110-L166 HydrophobicContact CD2-CD2 3.63Å; L110-L166 HydrophobicContact CD2-CG 4.01Å; L110-L166 HydrophobicContact CG-CD2 4.45Å; L110-V167 HydrophobicContact CD1-CG2 3.62Å; L110-I170 HydrophobicContact CD1-CD1 4.11Å; L110-I170 HydrophobicContact CD2-CD1 4.09Å; L110-I170 HydrophobicContact CG-CD1 4.28Å
111R98.8Very high98.7Very high1 Ų129.7 Ų29.70%0.00414%0.141CC..Hα-helixtrans-58.8-47.8175.9172.4170.8177.676.4-3112.2V106 S107 Q108 R109 V114 L115 H128 V131 L133 D466 N518V106-R111 HydrophobicContact CG1-CB 4.26Å; S107-R111 PolarHBondContact O-N 2.86Å; Q108-R111 PolarHBondContact O-N 2.81Å; R109-R111 VanDerWaalsContact C-N 3.31Å; R109-R111 PolarHBondContact O-N 3.02Å; R111-V114 PolarHBondContact O-N 3.37Å; R111-L115 HydrophobicContact CG-CD1 3.81Å; R111-L115 HydrophobicContact CG-CG 4.32Å; R111-L115 WeakPolarHBondContact O-CB 3.37Å; R111-L115 VanDerWaalsContact O-CG 3.31Å; R111-L115 WeakPolarHBondContact O-CG 3.19Å; R111-L115 PolarHBondContact O-N 2.85Å; R111-H128 PolarHBondContact NH2-O 3.43Å; R111-V131 PolarHBondContact NH1-O 2.78Å; R111-L133 HydrophobicContact CB-CD1 4.28Å; R111-L133 HydrophobicContact CG-CD1 4.48Å; R111-D466 IonicContact CZ-OD1 3.34Å; R111-D466 IonicContact NE-OD1 2.81Å; R111-D466 PolarHBondContact NE-OD1 3.43Å; R111-D466 IonicContact NH2-OD1 2.82Å; R111-D466 PolarHBondContact NH2-OD1 3.05Å; R111-N518 VanDerWaalsContact CB-O 3.31Å; R111-N518 WeakPolarHBondContact CB-O 3.39Å; R111-N518 VanDerWaalsContact CD-CB 3.41Å; R111-N518 VanDerWaalsContact CD-O 3.32Å; R111-N518 WeakPolarHBondContact CD-O 3.3Å; R111-N518 VanDerWaalsContact CZ-CG 3.47Å; R111-N518 PolarHBondContact NH1-OD1 3.25Å
112L98.8Very high98.7Very high27 Ų2731.6 Ų31.614%0.14115%0.148CC..Hα-helixtrans-64.9-41-179.3-68.1172.6000112.1Q108 R109 L110 L115 Q116 P575 F577Q108-L112 HydrophobicContact CG-CD1 4.12Å; Q108-L112 WeakPolarHBondContact O-CB 3.35Å; Q108-L112 WeakPolarHBondContact O-CG 3.09Å; Q108-L112 PolarHBondContact O-N 2.83Å; R109-L112 PolarHBondContact O-N 3.41Å; L110-L112 PolarHBondContact O-N 3.5Å; L112-L115 PolarHBondContact O-N 2.68Å; L112-Q116 VanDerWaalsContact O-CB 3.29Å; L112-Q116 WeakPolarHBondContact O-CB 3.39Å; L112-Q116 PolarHBondContact O-N 3.19Å; L112-P575 HydrophobicContact CD1-CG 4.25Å; L112-P575 HydrophobicContact CD2-CG 4.15Å; L112-F577 HydrophobicContact CB-CD2 3.79Å; L112-F577 HydrophobicContact CB-CE2 4.1Å; L112-F577 HydrophobicContact CD1-CB 4.26Å; L112-F577 HydrophobicContact CD1-CD2 3.87Å; L112-F577 HydrophobicContact CG-CD2 4.5Å
113E98.7Very high98.7Very high33 Ų3333.1 Ų33.115%0.15417%0.165CC..Hα-helixtrans-64.5-42175.6-70.5-173.4-171.200111.9R109 L110 Q116 A117 Y158 V163 V167 F577R109-E113 HydrophobicContact CG-CG 4.39Å; R109-E113 IonicContact CZ-OE1 3.39Å; R109-E113 IonicContact NE-OE1 3.27Å; R109-E113 PolarHBondContact NE-OE1 2.94Å; R109-E113 IonicContact NH2-OE1 2.71Å; R109-E113 PolarHBondContact NH2-OE1 2.87Å; R109-E113 WeakPolarHBondContact O-CG 3.31Å; R109-E113 PolarHBondContact O-N 2.9Å; L110-E113 PolarHBondContact O-N 3.37Å; E113-Q116 PolarHBondContact O-N 3.23Å; E113-A117 WeakPolarHBondContact O-CB 3.49Å; E113-A117 PolarHBondContact O-N 3.21Å; E113-Y158 PolarHBondContact OE1-OH 2.78Å; E113-V163 VanDerWaalsContact OE2-CG1 3.3Å; E113-V163 WeakPolarHBondContact OE2-CG1 3.18Å; E113-V167 HydrophobicContact CB-CG1 4.36Å; E113-V167 HydrophobicContact CB-CG2 3.9Å; E113-V167 WeakPolarHBondContact OE2-CG2 3.44Å; E113-F577 HydrophobicContact CG-CE2 3.78Å; E113-F577 HydrophobicContact CG-CZ 3.91Å
114V98.9Very high98.6Very high0 Ų038.4 Ų38.40%019%0.193CC..Hα-helixtrans-64-47.7175.21690000111.4L110 R111 Q116 A117 L118 L133 V167 I170 V171L110-V114 HydrophobicContact CD1-CG2 4.18Å; L110-V114 WeakPolarHBondContact O-CB 3.48Å; L110-V114 VanDerWaalsContact O-CG2 3.32Å; L110-V114 WeakPolarHBondContact O-CG2 3.36Å; L110-V114 PolarHBondContact O-N 3.45Å; R111-V114 PolarHBondContact O-N 3.37Å; V114-Q116 VanDerWaalsContact C-N 3.29Å; V114-Q116 PolarHBondContact O-N 3.39Å; V114-A117 PolarHBondContact O-N 2.79Å; V114-L118 HydrophobicContact CG1-CD1 3.84Å; V114-L118 HydrophobicContact CG1-CG 4.28Å; V114-L118 WeakPolarHBondContact O-CB 3.48Å; V114-L118 VanDerWaalsContact O-CG 3.29Å; V114-L118 WeakPolarHBondContact O-CG 3.34Å; V114-L118 PolarHBondContact O-N 2.94Å; V114-L133 HydrophobicContact CB-CD1 4.03Å; V114-L133 HydrophobicContact CG1-CD1 3.95Å; V114-L133 HydrophobicContact CG1-CD2 4.45Å; V114-L133 HydrophobicContact CG2-CD1 4.3Å; V114-V167 HydrophobicContact CG2-CB 4.49Å; V114-V167 HydrophobicContact CG2-CG1 4.16Å; V114-V167 HydrophobicContact CG2-CG2 4.49Å; V114-I170 HydrophobicContact CB-CG2 4.5Å; V114-I170 HydrophobicContact CG1-CG2 3.75Å; V114-I170 HydrophobicContact CG2-CB 4.06Å; V114-I170 HydrophobicContact CG2-CD1 4.26Å; V114-I170 HydrophobicContact CG2-CG2 3.89Å; V114-V171 HydrophobicContact CG1-CG2 4.29Å
115L98.8Very high98.6Very high20 Ų2041.1 Ų41.111%0.10521%0.207CC..Hα-helixtrans-63.3-36.9179-72.6175.5000111.8R111 L112 L118 K119 H128 V131R111-L115 HydrophobicContact CG-CD1 3.81Å; R111-L115 HydrophobicContact CG-CG 4.32Å; R111-L115 WeakPolarHBondContact O-CB 3.37Å; R111-L115 VanDerWaalsContact O-CG 3.31Å; R111-L115 WeakPolarHBondContact O-CG 3.19Å; R111-L115 PolarHBondContact O-N 2.85Å; L112-L115 PolarHBondContact O-N 2.68Å; L115-L118 PolarHBondContact O-N 3.12Å; L115-K119 VanDerWaalsContact O-CB 3.29Å; L115-K119 WeakPolarHBondContact O-CB 3.46Å; L115-K119 PolarHBondContact O-N 3.43Å; L115-H128 HydrophobicContact CD1-CB 4.06Å; L115-V131 HydrophobicContact CD2-CB 4.09Å; L115-V131 HydrophobicContact CD2-CG1 4.39Å; L115-V131 HydrophobicContact CD2-CG2 4.33Å
116Q98.6Very high98.6Very high97 Ų9740.9 Ų40.945%0.45321%0.205SC..Hα-helixtrans-63.2-48.4174-179.559.334.300111.2L112 E113 V114 L118 K119 E120L112-Q116 VanDerWaalsContact O-CB 3.29Å; L112-Q116 WeakPolarHBondContact O-CB 3.39Å; L112-Q116 PolarHBondContact O-N 3.19Å; E113-Q116 PolarHBondContact O-N 3.23Å; V114-Q116 VanDerWaalsContact C-N 3.29Å; V114-Q116 PolarHBondContact O-N 3.39Å; Q116-L118 VanDerWaalsContact C-N 3.34Å; Q116-L118 PolarHBondContact O-N 3.12Å; Q116-K119 PolarHBondContact O-N 2.89Å; Q116-E120 PolarHBondContact NE2-OE1 3.05Å; Q116-E120 WeakPolarHBondContact O-CG 3.4Å; Q116-E120 PolarHBondContact O-N 3.18Å
117A98.8Very high98.6Very high27 Ų2744.3 Ų44.322%0.22322%0.218CC..Hα-helixtrans-63.2-38.9177.700000112.6E113 V114 E120 K121 V171E113-A117 WeakPolarHBondContact O-CB 3.49Å; E113-A117 PolarHBondContact O-N 3.21Å; V114-A117 PolarHBondContact O-N 2.79Å; A117-E120 PolarHBondContact O-N 2.83Å; A117-K121 PolarHBondContact O-N 3.39Å; A117-K121 VanDerWaalsContact O-N 3.16Å; A117-V171 HydrophobicContact CB-CG2 3.75Å
118L98.9Very high98.5Very high0 Ų047.1 Ų47.10%023%0.231CC..Hα-helixtrans-65.4-41.6174.1-70.8172.9000111.6V114 L115 Q116 K121 Y122 Y126 V131 V171 I174V114-L118 HydrophobicContact CG1-CD1 3.84Å; V114-L118 HydrophobicContact CG1-CG 4.28Å; V114-L118 WeakPolarHBondContact O-CB 3.48Å; V114-L118 VanDerWaalsContact O-CG 3.29Å; V114-L118 WeakPolarHBondContact O-CG 3.34Å; V114-L118 PolarHBondContact O-N 2.94Å; L115-L118 PolarHBondContact O-N 3.12Å; Q116-L118 VanDerWaalsContact C-N 3.34Å; Q116-L118 PolarHBondContact O-N 3.12Å; L118-K121 PolarHBondContact O-N 3.33Å; L118-Y122 HydrophobicContact CD2-CD2 4.07Å; L118-Y122 HydrophobicContact CD2-CE2 4.28Å; L118-Y122 WeakPolarHBondContact O-CA 3.39Å; L118-Y122 VanDerWaalsContact O-CB 3.31Å; L118-Y122 WeakPolarHBondContact O-CB 3.35Å; L118-Y122 PolarHBondContact O-N 2.97Å; L118-Y126 HydrophobicContact CD2-CD2 4.18Å; L118-V131 HydrophobicContact CD1-CG2 4.44Å; L118-V171 HydrophobicContact CD2-CG1 4.4Å; L118-I174 HydrophobicContact CD1-CD1 3.76Å; L118-I174 HydrophobicContact CD2-CB 4.33Å; L118-I174 HydrophobicContact CD2-CD1 4.16Å; L118-I174 HydrophobicContact CD2-CG2 3.89Å
119K98.6Very high98.5Very high119 Ų11948.3 Ų48.352%0.51724%0.238SC..Hα-helixtrans-63.2-41.8176.8-175.8177.2-177.8178.30112L115 Q116 K121 G123L115-K119 VanDerWaalsContact O-CB 3.29Å; L115-K119 WeakPolarHBondContact O-CB 3.46Å; L115-K119 PolarHBondContact O-N 3.43Å; Q116-K119 PolarHBondContact O-N 2.89Å; K119-K121 VanDerWaalsContact C-N 3.3Å; K119-K121 PolarHBondContact O-N 3.07Å; K119-G123 VanDerWaalsContact O-CA 3.26Å; K119-G123 WeakPolarHBondContact O-CA 3.38Å; K119-G123 PolarHBondContact O-N 3.41Å
120E98.6Very high98.5Very high145 Ų14547.6 Ų47.668%0.67824%0.235SC*.Hα-helixtrans-61.1-38.3176-75.1171.8-16700112.3Q116 A117Q116-E120 PolarHBondContact NE2-OE1 3.05Å; Q116-E120 WeakPolarHBondContact O-CG 3.4Å; Q116-E120 PolarHBondContact O-N 3.18Å; A117-E120 PolarHBondContact O-N 2.83Å
121K98.6Very high98.5Very high113 Ų11347.6 Ų47.649%0.49124%0.235SC..Hα-helixtrans-86.4-36.5-177.7-174.2166.1176.9170.10114.1A117 L118 K119 D175A117-K121 PolarHBondContact O-N 3.39Å; A117-K121 VanDerWaalsContact O-N 3.16Å; L118-K121 PolarHBondContact O-N 3.33Å; K119-K121 VanDerWaalsContact C-N 3.3Å; K119-K121 PolarHBondContact O-N 3.07Å; K121-D175 WeakPolarHBondContact CE-OD1 2.96Å; K121-D175 IonicContact NZ-OD1 2.85Å; K121-D175 PolarHBondContact NZ-OD1 2.89Å; K121-D175 IonicContact NZ-OD2 3.01Å; K121-D175 PolarHBondContact NZ-OD2 2.82Å
122Y98.6Very high98.5Very high41 Ų4147.5 Ų47.516%0.16124%0.235CC..Hα-helixtrans-1233-166.3-67.5-71.5000114.4L118 D124 L125 Y126 D175 H178L118-Y122 HydrophobicContact CD2-CD2 4.07Å; L118-Y122 HydrophobicContact CD2-CE2 4.28Å; L118-Y122 WeakPolarHBondContact O-CA 3.39Å; L118-Y122 VanDerWaalsContact O-CB 3.31Å; L118-Y122 WeakPolarHBondContact O-CB 3.35Å; L118-Y122 PolarHBondContact O-N 2.97Å; Y122-D124 PolarHBondContact O-N 3.43Å; Y122-L125 HydrophobicContact CD1-CD2 4.25Å; Y122-L125 WeakPolarHBondContact O-CB 3.24Å; Y122-L125 PolarHBondContact O-N 2.81Å; Y122-Y126 HydrophobicContact CD1-CD2 4.43Å; Y122-Y126 AromaticContact CD1-CE2 4Å; Y122-Y126 HydrophobicContact CD1-CE2 4Å; Y122-Y126 AromaticContact CD2-CD2 3.62Å; Y122-Y126 HydrophobicContact CD2-CD2 3.62Å; Y122-Y126 AromaticContact CD2-CE2 3.71Å; Y122-Y126 HydrophobicContact CD2-CE2 3.71Å; Y122-Y126 HydrophobicContact CE1-CE2 4.24Å; Y122-Y126 HydrophobicContact CE2-CD2 4.27Å; Y122-Y126 AromaticContact CE2-CE2 3.98Å; Y122-Y126 HydrophobicContact CE2-CE2 3.98Å; Y122-Y126 AromaticContact CG-CD2 3.7Å; Y122-Y126 HydrophobicContact CG-CD2 3.7Å; Y122-Y126 AromaticContact CG-CE2 3.7Å; Y122-Y126 HydrophobicContact CG-CE2 3.7Å; Y122-D175 PolarHBondContact OH-OD1 3.06Å; Y122-H178 AromaticContact CE1-CD2 3.45Å; Y122-H178 VanDerWaalsContact CE1-CD2 3.45Å; Y122-H178 WeakPolarHBondContact CE1-CD2 3.5Å; Y122-H178 AromaticContact CE1-CG 3.98Å; Y122-H178 AromaticContact CE1-NE2 3.55Å; Y122-H178 AromaticContact CZ-CD2 3.83Å; Y122-H178 PolarHBondContact OH-CD2 2.87Å
123G98.4Very high98.5Very high34 Ų3446.3 Ų46.335%0.35123%0.228SC..G310 helixtrans59.9-132.9-175.500000111.5K119 L125K119-G123 VanDerWaalsContact O-CA 3.26Å; K119-G123 WeakPolarHBondContact O-CA 3.38Å; K119-G123 PolarHBondContact O-N 3.41Å; G123-L125 VanDerWaalsContact C-N 3.28Å; G123-L125 PolarHBondContact O-N 2.98Å
124D97.6Very high98.6Very high117 Ų11744.7 Ų44.763%0.62622%0.221SC*.G310 helixtrans-87.813.4-176.3-62.4-47.1000114Y122 R127Y122-D124 PolarHBondContact O-N 3.43Å; D124-R127 VanDerWaalsContact O-CD 3.27Å; D124-R127 WeakPolarHBondContact O-CD 3.41Å; D124-R127 VanDerWaalsContact O-CG 3.23Å; D124-R127 WeakPolarHBondContact O-CG 3.19Å; D124-R127 PolarHBondContact O-NH1 2.96Å
125L98.4Very high98.5Very high57 Ų5744.7 Ų44.730%0.29822%0.221SC..G310 helixtrans-69.5-42.1-179.7-179.861000112.5Y122 G123 N130Y122-L125 HydrophobicContact CD1-CD2 4.25Å; Y122-L125 WeakPolarHBondContact O-CB 3.24Å; Y122-L125 PolarHBondContact O-N 2.81Å; G123-L125 VanDerWaalsContact C-N 3.28Å; G123-L125 PolarHBondContact O-N 2.98Å; L125-N130 PolarHBondContact O-ND2 3.48Å
126Y98.7Very high98.5Very high3 Ų343.8 Ų43.81%0.01222%0.216CC..SBendtrans-117.8113-179.4-59.5-52.4000109.8I88 R95 V97 L118 Y122 V131 I174 H178I88-Y126 HydrophobicContact CD1-CE1 4.21Å; I88-Y126 WeakPolarHBondContact CD1-OH 3.31Å; R95-Y126 HydrophobicContact CG-CE1 4.4Å; R95-Y126 PolarHBondContact NH1-OH 2.9Å; V97-Y126 HydrophobicContact CG2-CD1 3.42Å; V97-Y126 VanDerWaalsContact CG2-CD1 3.42Å; V97-Y126 HydrophobicContact CG2-CE1 3.43Å; V97-Y126 VanDerWaalsContact CG2-CE1 3.43Å; V97-Y126 HydrophobicContact CG2-CG 4.44Å; L118-Y126 HydrophobicContact CD2-CD2 4.18Å; Y122-Y126 HydrophobicContact CD1-CD2 4.43Å; Y122-Y126 AromaticContact CD1-CE2 4Å; Y122-Y126 HydrophobicContact CD1-CE2 4Å; Y122-Y126 AromaticContact CD2-CD2 3.62Å; Y122-Y126 HydrophobicContact CD2-CD2 3.62Å; Y122-Y126 AromaticContact CD2-CE2 3.71Å; Y122-Y126 HydrophobicContact CD2-CE2 3.71Å; Y122-Y126 HydrophobicContact CE1-CE2 4.24Å; Y122-Y126 HydrophobicContact CE2-CD2 4.27Å; Y122-Y126 AromaticContact CE2-CE2 3.98Å; Y122-Y126 HydrophobicContact CE2-CE2 3.98Å; Y122-Y126 AromaticContact CG-CD2 3.7Å; Y122-Y126 HydrophobicContact CG-CD2 3.7Å; Y122-Y126 AromaticContact CG-CE2 3.7Å; Y122-Y126 HydrophobicContact CG-CE2 3.7Å; Y126-V131 HydrophobicContact CD1-CG2 4.42Å; Y126-V131 HydrophobicContact CG-CG2 4.49Å; Y126-I174 HydrophobicContact CD2-CG2 4.44Å; Y126-I174 HydrophobicContact CE2-CG2 4.2Å; Y126-H178 AromaticContact CZ-ND1 3.93Å; Y126-H178 WeakPolarHBondContact OH-CB 3.08Å; Y126-H178 PolarHBondContact OH-ND1 3.19Å
127R98.2Very high98.6Very high75 Ų7539.2 Ų39.228%0.28320%0.195SC..  trans-132.1173.1-167.3-61.7-177-48.5-77.9-4.6110.4D124 D129 N130 V131D124-R127 VanDerWaalsContact O-CD 3.27Å; D124-R127 WeakPolarHBondContact O-CD 3.41Å; D124-R127 VanDerWaalsContact O-CG 3.23Å; D124-R127 WeakPolarHBondContact O-CG 3.19Å; D124-R127 PolarHBondContact O-NH1 2.96Å; R127-D129 WeakPolarHBondContact CB-OD1 3.4Å; R127-D129 IonicContact CZ-OD1 2.9Å; R127-D129 IonicContact CZ-OD2 3.51Å; R127-D129 IonicContact NE-OD1 3.63Å; R127-D129 PolarHBondContact NE-OD1 3.05Å; R127-D129 IonicContact NE-OD2 3.84Å; R127-D129 PolarHBondContact NE-OD2 2.82Å; R127-D129 IonicContact NH2-OD1 2.94Å; R127-D129 PolarHBondContact NH2-OD1 2.98Å; R127-D129 IonicContact NH2-OD2 2.78Å; R127-D129 PolarHBondContact NH2-OD2 2.96Å; R127-D129 PolarHBondContact O-N 3.33Å; R127-N130 PolarHBondContact N-OD1 3.4Å; R127-N130 PolarHBondContact O-N 2.82Å; R127-N130 PolarHBondContact O-OD1 2.72Å; R127-V131 WeakPolarHBondContact O-CB 3.2Å; R127-V131 WeakPolarHBondContact O-CG2 2.94Å; R127-V131 PolarHBondContact O-N 3.33Å; R127-V131 VanDerWaalsContact O-N 3.07Å
128H97.4Very high98.6Very high59 Ų5937.9 Ų37.927%0.27318%0.184SC..THydrogen-bonded Turntrans-58.6-31.5178.757.1-94.8000113R111 L115 H370 W372 Q468R111-H128 PolarHBondContact NH2-O 3.43Å; L115-H128 HydrophobicContact CD1-CB 4.06Å; H128-H370 AromaticContact CD2-CE1 3.72Å; H128-H370 AromaticContact CD2-CG 3.87Å; H128-H370 AromaticContact CD2-ND1 3.32Å; H128-H370 PolarHBondContact CD2-ND1 3.01Å; H128-H370 VanDerWaalsContact CD2-ND1 3.32Å; H128-W372 HydrophobicContact CB-CZ2 4.1Å; H128-W372 AromaticContact ND1-CH2 3.99Å; H128-Q468 PolarHBondContact O-NE2 3.34Å
129D98.2Very high98.5Very high28 Ų2838.6 Ų38.615%0.1519%0.187CC..THydrogen-bonded Turntrans-79.6-30.5-176.257.5-35.2000113.8R127 F368 H370 Q468R127-D129 WeakPolarHBondContact CB-OD1 3.4Å; R127-D129 IonicContact CZ-OD1 2.9Å; R127-D129 IonicContact CZ-OD2 3.51Å; R127-D129 IonicContact NE-OD1 3.63Å; R127-D129 PolarHBondContact NE-OD1 3.05Å; R127-D129 IonicContact NE-OD2 3.84Å; R127-D129 PolarHBondContact NE-OD2 2.82Å; R127-D129 IonicContact NH2-OD1 2.94Å; R127-D129 PolarHBondContact NH2-OD1 2.98Å; R127-D129 IonicContact NH2-OD2 2.78Å; R127-D129 PolarHBondContact NH2-OD2 2.96Å; R127-D129 PolarHBondContact O-N 3.33Å; D129-F368 HydrophobicContact CB-CD2 3.88Å; D129-F368 HydrophobicContact CB-CE2 4.16Å; D129-F368 WeakPolarHBondContact O-CB 3.29Å; D129-F368 WeakPolarHBondContact OD2-CE2 3.34Å; D129-H370 HydrophobicContact CB-CB 3.97Å; D129-Q468 VanDerWaalsContact C-NE2 3.27Å; D129-Q468 PolarHBondContact O-NE2 2.97Å
130N98.8Very high98.5Very high3 Ų332.9 Ų32.92%0.01616%0.163CC..THydrogen-bonded Turntrans-113.31.8-17774.9-23.1000115.5R95 V96 V97 L125 R127 F368R95-N130 VanDerWaalsContact O-CB 3.3Å; R95-N130 WeakPolarHBondContact O-CB 3.23Å; R95-N130 PolarHBondContact O-ND2 3.34Å; V96-N130 CarbonylContact C-O 3.57Å; V96-N130 WeakPolarHBondContact CA-O 3.47Å; V96-N130 HydrophobicContact CG1-CB 4.38Å; V97-N130 PolarHBondContact N-O 3.48Å; L125-N130 PolarHBondContact O-ND2 3.48Å; R127-N130 PolarHBondContact N-OD1 3.4Å; R127-N130 PolarHBondContact O-N 2.82Å; R127-N130 PolarHBondContact O-OD1 2.72Å; N130-F368 HydrophobicContact CB-CD1 3.7Å; N130-F368 HydrophobicContact CB-CD2 4.33Å; N130-F368 HydrophobicContact CB-CE1 3.78Å; N130-F368 HydrophobicContact CB-CE2 4.47Å; N130-F368 HydrophobicContact CB-CG 3.98Å; N130-F368 HydrophobicContact CB-CZ 4.19Å
131V98.9Very high98.5Very high0 Ų026.2 Ų26.20%013%0.132CC..EExtended strand (participates in β ladder)trans-112.2120.6173.5-178.90000110.8V97 R111 L115 L118 Y126 R127 L133 Q468V97-V131 HydrophobicContact CB-CG1 4.39Å; V97-V131 HydrophobicContact CB-CG2 4.15Å; V97-V131 HydrophobicContact CG2-CG2 4.19Å; R111-V131 PolarHBondContact NH1-O 2.78Å; L115-V131 HydrophobicContact CD2-CB 4.09Å; L115-V131 HydrophobicContact CD2-CG1 4.39Å; L115-V131 HydrophobicContact CD2-CG2 4.33Å; L118-V131 HydrophobicContact CD1-CG2 4.44Å; Y126-V131 HydrophobicContact CD1-CG2 4.42Å; Y126-V131 HydrophobicContact CG-CG2 4.49Å; R127-V131 WeakPolarHBondContact O-CB 3.2Å; R127-V131 WeakPolarHBondContact O-CG2 2.94Å; R127-V131 PolarHBondContact O-N 3.33Å; R127-V131 VanDerWaalsContact O-N 3.07Å; V131-L133 HydrophobicContact CG1-CD2 3.84Å; V131-L133 HydrophobicContact CG1-CG 4.27Å; V131-Q468 PolarHBondContact O-NE2 2.69Å; V131-Q468 PolarHBondContact O-OE1 2.52Å
132V98.9Very high98.5Very high0 Ų021.3 Ų21.30%011%0.112CC..EExtended strand (participates in β ladder)trans-106.6128.5170.6175.50000109V97 F98 V99 Q468 I470 A479V97-V132 PolarHBondContact O-N 3.43Å; F98-V132 HydrophobicContact CD2-CB 3.93Å; F98-V132 HydrophobicContact CD2-CG1 3.69Å; F98-V132 HydrophobicContact CE2-CG1 3.79Å; V99-V132 PolarHBondContact N-O 2.83Å; V132-Q468 HydrophobicContact CG2-CG 4.18Å; V132-I470 HydrophobicContact CG2-CD1 4.04Å; V132-I470 HydrophobicContact CG2-CG1 4.26Å; V132-I470 HydrophobicContact CG2-CG2 3.83Å; V132-A479 HydrophobicContact CG1-CB 3.7Å; V132-A479 HydrophobicContact CG2-CB 4.03Å
133L98.9Very high98.4Very high1 Ų119.4 Ų19.41%0.00511%0.105CC..EExtended strand (participates in β ladder)trans-114.8121.5171.1-53.7-179.1000108.6V99 V106 R111 V114 V131 I170 S517 N518V99-L133 HydrophobicContact CB-CD2 3.72Å; V99-L133 HydrophobicContact CG1-CD2 4.35Å; V99-L133 HydrophobicContact CG2-CD2 3.68Å; V106-L133 HydrophobicContact CG1-CB 4Å; V106-L133 HydrophobicContact CG1-CD1 4.46Å; V106-L133 HydrophobicContact CG2-CB 4.04Å; V106-L133 WeakPolarHBondContact CG2-O 3.31Å; R111-L133 HydrophobicContact CB-CD1 4.28Å; R111-L133 HydrophobicContact CG-CD1 4.48Å; V114-L133 HydrophobicContact CB-CD1 4.03Å; V114-L133 HydrophobicContact CG1-CD1 3.95Å; V114-L133 HydrophobicContact CG1-CD2 4.45Å; V114-L133 HydrophobicContact CG2-CD1 4.3Å; V131-L133 HydrophobicContact CG1-CD2 3.84Å; V131-L133 HydrophobicContact CG1-CG 4.27Å; L133-I170 HydrophobicContact CD2-CG2 3.9Å; L133-S517 CarbonylContact O-C 3.6Å; L133-S517 WeakPolarHBondContact O-CA 3.39Å; L133-N518 PolarHBondContact N-OD1 2.77Å; L133-N518 VanDerWaalsContact N-OD1 3.14Å; L133-N518 PolarHBondContact O-N 3.09Å
134S98.9Very high98.4Very high0 Ų017.8 Ų17.80%09%0.088CC..EExtended strand (participates in β ladder)trans-124.4142.3-179.9177.10000111.4V99 T100 A101 G515 S517V99-S134 PolarHBondContact O-N 2.99Å; T100-S134 CarbonylContact C-O 3.58Å; T100-S134 WeakPolarHBondContact CA-O 3.43Å; A101-S134 PolarHBondContact N-O 3.31Å; S134-G515 PolarHBondContact OG-O 3.44Å; S134-S517 WeakPolarHBondContact CB-OG 3.39Å
135G98.8Very high98.4Very high0 Ų012.4 Ų12.40%06%0.059CC..EExtended strand (participates in β ladder)trans-93.1143.4172.900000112.1A101 H137 S290 L516A101-G135 WeakPolarHBondContact O-CA 3.36Å; G135-H137 PolarHBondContact O-N 3.17Å; G135-S290 WeakPolarHBondContact O-CB 3.5Å; G135-S290 PolarHBondContact O-OG 3.31Å; G135-L516 PolarHBondContact N-O 3.07Å
136T98.8Very high98.4Very high1 Ų19.9 Ų9.91%0.0065%0.046CC..  trans-67.2-17.1170.761.50000113A101 D102 F288A101-T136 WeakPolarHBondContact O-CG2 2.95Å; A101-T136 PolarHBondContact O-N 2.79Å; D102-T136 WeakPolarHBondContact OD1-CG2 3.38Å; T136-F288 WeakPolarHBondContact CG2-O 3.46Å
137H98.8Very high98.3Very high0 Ų09.8 Ų9.80%05%0.045CC..  trans7332.2-175.5-156.840.7000115.2V103 G104 G135 H139 H246 A247 L293 E483 L516V103-H137 PolarHBondContact O-N 3.22Å; G104-H137 VanDerWaalsContact O-CA 3.28Å; G104-H137 WeakPolarHBondContact O-CA 3.43Å; G104-H137 PolarHBondContact O-ND1 3.5Å; G135-H137 PolarHBondContact O-N 3.17Å; H137-H139 AromaticContact CD2-NE2 3.72Å; H137-H139 AromaticContact CE1-CD2 3.97Å; H137-H139 AromaticContact CE1-NE2 3.2Å; H137-H139 PolarHBondContact CE1-NE2 3.45Å; H137-H139 AromaticContact ND1-NE2 3.78Å; H137-H139 AromaticContact NE2-NE2 3.08Å; H137-H139 PolarHBondContact NE2-NE2 3.25Å; H137-H139 PolarHBondContact O-CD2 2.92Å; H137-H139 VanDerWaalsContact O-CD2 3.29Å; H137-H139 PolarHBondContact O-N 2.88Å; H137-H246 AromaticContact CD2-CD2 3.2Å; H137-H246 PolarHBondContact CD2-CD2 3.28Å; H137-H246 AromaticContact CD2-NE2 3.52Å; H137-H246 AromaticContact NE2-CD2 3.21Å; H137-H246 PolarHBondContact NE2-CD2 2.99Å; H137-H246 AromaticContact NE2-NE2 3.25Å; H137-H246 PolarHBondContact NE2-NE2 3.11Å; H137-A247 VanDerWaalsContact O-CB 3.31Å; H137-A247 WeakPolarHBondContact O-CB 3.49Å; H137-L293 HydrophobicContact CB-CD2 4.08Å; H137-E483 IonicContact CD2-OE2 2.58Å; H137-E483 IonicContact CE1-OE1 3.67Å; H137-E483 IonicContact CE1-OE2 2.69Å; H137-E483 IonicContact NE2-OE1 3.24Å; H137-E483 IonicContact NE2-OE2 3.82Å; H137-E483 PolarHBondContact NE2-OE2 3.37Å; H137-L516 HydrophobicContact CB-CD1 4.02Å; H137-L516 HydrophobicContact CB-CD2 3.59Å; H137-L516 HydrophobicContact CB-CG 4.47Å; H137-L516 WeakPolarHBondContact ND1-CD2 3.46Å
138T98.8Very high98.3Very high0 Ų06.5 Ų6.50%03%0.033CC..BIsolated β-bridgetrans-64.4130.3168175.80000111.2G104 C140 S258G104-T138 WeakPolarHBondContact CA-O 3.47Å; G104-T138 PolarHBondContact N-O 2.85Å; T138-C140 PolarHBondContact O-N 3.43Å; T138-C140 PolarHBondContact OG1-N 2.96Å; T138-C140 VanDerWaalsContact OG1-N 3.16Å; T138-S258 PolarHBondContact OG1-O 3.15Å
139H98.6Very high98.3Very high14 Ų143.8 Ų3.87%0.0652%0.02CC..THydrogen-bonded Turntrans-87.114.3174-75.2-138000113.1M66 G67 Y68 H137 A247 V248M66-H139 CarbonylContact O-C 3.57Å; M66-H139 VanDerWaalsContact O-C 3.24Å; M66-H139 WeakPolarHBondContact O-CA 3.48Å; G67-H139 VanDerWaalsContact C-ND1 3.33Å; G67-H139 VanDerWaalsContact CA-ND1 3.26Å; G67-H139 WeakPolarHBondContact CA-ND1 3.23Å; Y68-H139 AromaticContact CD1-ND1 3.9Å; Y68-H139 HydrophobicContact CD2-CB 3.76Å; Y68-H139 AromaticContact CD2-ND1 4Å; Y68-H139 AromaticContact CE1-ND1 3.92Å; Y68-H139 HydrophobicContact CE2-CB 3.43Å; Y68-H139 VanDerWaalsContact CE2-CB 3.43Å; Y68-H139 AromaticContact CG-ND1 3.94Å; Y68-H139 AromaticContact CZ-ND1 4Å; Y68-H139 PolarHBondContact N-ND1 2.89Å; H137-H139 AromaticContact CD2-NE2 3.72Å; H137-H139 AromaticContact CE1-CD2 3.97Å; H137-H139 AromaticContact CE1-NE2 3.2Å; H137-H139 PolarHBondContact CE1-NE2 3.45Å; H137-H139 AromaticContact ND1-NE2 3.78Å; H137-H139 AromaticContact NE2-NE2 3.08Å; H137-H139 PolarHBondContact NE2-NE2 3.25Å; H137-H139 PolarHBondContact O-CD2 2.92Å; H137-H139 VanDerWaalsContact O-CD2 3.29Å; H137-H139 PolarHBondContact O-N 2.88Å; H139-A247 PolarHBondContact N-O 2.72Å; H139-V248 HydrophobicContact CB-CG1 4.19Å; H139-V248 VanDerWaalsContact CD2-CG1 3.43Å; H139-V248 WeakPolarHBondContact CD2-CG1 3.08Å
140C98.4Very high98.2Very high0 Ų03.1 Ų3.10%02%0.017CC..THydrogen-bonded Turntrans-118.815.3-175.5-59.80000113.4T138 M250 N254 V257 S258T138-C140 PolarHBondContact O-N 3.43Å; T138-C140 PolarHBondContact OG1-N 2.96Å; T138-C140 VanDerWaalsContact OG1-N 3.16Å; C140-M250 WeakPolarHBondContact SG-CB 3.4Å; C140-N254 PolarHBondContact SG-ND2 3.18Å; C140-V257 VanDerWaalsContact O-CA 3.31Å; C140-V257 WeakPolarHBondContact O-CA 3.49Å; C140-S258 VanDerWaalsContact CB-O 3.29Å; C140-S258 WeakPolarHBondContact CB-O 3.39Å; C140-S258 PolarHBondContact O-N 3.46Å
141G98.1Very high98.1Very high4 Ų43.6 Ų3.64%0.0412%0.019CC..EExtended strand (participates in β ladder)trans-90.3148.2174.900000113.3L65 M66 A143L65-G141 CarbonylContact C-O 3.56Å; L65-G141 WeakPolarHBondContact CA-O 3.43Å; M66-G141 PolarHBondContact N-O 2.88Å; G141-A143 PolarHBondContact O-N 3.45Å
142P97.7Very high97.9Very high11 Ų113.6 Ų3.67%0.0712%0.019CC..EExtended strand (participates in β ladder)trans-56.7135.5172.8-24.634.4000112.9I63 Y145 A162 V257I63-P142 HydrophobicContact CG2-CB 3.95Å; P142-Y145 WeakPolarHBondContact O-CE1 3.26Å; P142-A162 HydrophobicContact CB-CB 4.37Å; P142-V257 HydrophobicContact CG-CG2 3.97Å
143A97.8Very high97.7Very high1 Ų17.3 Ų7.31%0.0084%0.038CC..  trans-79.9-173.5178.700000113.4P64 M66 G141 A162P64-A143 HydrophobicContact CB-CB 4.1Å; P64-A143 WeakPolarHBondContact O-CB 3.26Å; P64-A143 PolarHBondContact O-N 3.28Å; M66-A143 HydrophobicContact CB-CB 4.13Å; M66-A143 HydrophobicContact CE-CB 3.67Å; G141-A143 PolarHBondContact O-N 3.45Å; A143-A162 WeakPolarHBondContact O-CB 3.41Å
144G97.1Very high97.2Very high0 Ų010.4 Ų10.40%06%0.058CC..  trans94.620.8167.200000115.8S155 G157 Y158 I159 V163G144-S155 PolarHBondContact N-OG 3.16Å; G144-G157 VanDerWaalsContact CA-O 3.25Å; G144-G157 WeakPolarHBondContact CA-O 3.46Å; G144-Y158 CarbonylContact O-C 3.53Å; G144-Y158 WeakPolarHBondContact O-CA 3.43Å; G144-I159 PolarHBondContact O-N 3.4Å; G144-V163 WeakPolarHBondContact O-CG2 3.13Å
145Y97.9Very high97Very high3 Ų310.5 Ų10.51%0.0126%0.058CC..  trans-111.820.5-178.359.3-94.8000114.4M66 V103 M105 S107 L110 P142 L166M66-Y145 HydrophobicContact CB-CE1 4.37Å; M66-Y145 HydrophobicContact CE-CE1 4.39Å; M66-Y145 HydrophobicContact CG-CE1 4.38Å; M66-Y145 WeakPolarHBondContact CG-OH 3.48Å; V103-Y145 HydrophobicContact CG2-CE1 3.95Å; V103-Y145 HydrophobicContact CG2-CE2 4.06Å; V103-Y145 VanDerWaalsContact CG2-OH 3.27Å; V103-Y145 WeakPolarHBondContact CG2-OH 3.3Å; M105-Y145 PolarHBondContact N-OH 2.94Å; M105-Y145 WeakPolarHBondContact O-CE2 3.4Å; M105-Y145 PolarHBondContact O-OH 2.89Å; S107-Y145 WeakPolarHBondContact CB-O 3.36Å; S107-Y145 PolarHBondContact OG-O 3.49Å; L110-Y145 HydrophobicContact CD2-CD2 4.43Å; P142-Y145 WeakPolarHBondContact O-CE1 3.26Å; Y145-L166 HydrophobicContact CD1-CD2 4.13Å; Y145-L166 HydrophobicContact CD2-CD2 4.29Å; Y145-L166 HydrophobicContact CG-CD2 3.96Å
146F98.4Very high96.8Very high4 Ų414 Ų142%0.0187%0.073CC..  trans-103.7159.8178.1-72.8-99.3000112.1M66 M105 S107 F151 Y520M66-F146 HydrophobicContact CE-CD2 3.68Å; M66-F146 HydrophobicContact CE-CE2 3.43Å; M66-F146 VanDerWaalsContact CE-CE2 3.43Å; M66-F146 HydrophobicContact CG-CE2 4.41Å; M66-F146 HydrophobicContact SD-CE2 3.88Å; M105-F146 HydrophobicContact CB-CZ 4.34Å; M105-F146 HydrophobicContact SD-CZ 4.36Å; S107-F146 VanDerWaalsContact CB-CD1 3.44Å; F146-F151 HydrophobicContact CB-CB 3.56Å; F146-F151 HydrophobicContact CB-CD2 4.4Å; F146-F151 HydrophobicContact CB-CG 4.36Å; F146-F151 HydrophobicContact CD1-CB 3.64Å; F146-F151 HydrophobicContact CD1-CD1 4.41Å; F146-F151 AromaticContact CD1-CD2 3.39Å; F146-F151 HydrophobicContact CD1-CD2 3.39Å; F146-F151 HydrophobicContact CD1-CE2 4.15Å; F146-F151 AromaticContact CD1-CG 3.55Å; F146-F151 HydrophobicContact CD1-CG 3.55Å; F146-F151 HydrophobicContact CD2-CB 3.87Å; F146-F151 HydrophobicContact CD2-CG 4.49Å; F146-F151 HydrophobicContact CE1-CB 4.26Å; F146-F151 HydrophobicContact CE1-CD1 4.29Å; F146-F151 AromaticContact CE1-CD2 3.84Å; F146-F151 HydrophobicContact CE1-CD2 3.84Å; F146-F151 HydrophobicContact CE1-CE2 4.26Å; F146-F151 AromaticContact CE1-CG 3.86Å; F146-F151 HydrophobicContact CE1-CG 3.86Å; F146-F151 HydrophobicContact CE2-CB 4.46Å; F146-F151 HydrophobicContact CG-CB 3.42Å; F146-F151 VanDerWaalsContact CG-CB 3.42Å; F146-F151 HydrophobicContact CG-CD2 4.08Å; F146-F151 AromaticContact CG-CG 3.9Å; F146-F151 HydrophobicContact CG-CG 3.9Å; F146-F151 HydrophobicContact CZ-CG 4.45Å; F146-Y520 HydrophobicContact CE1-CD1 4.33Å
147Q97.9Very high96.7Very high1 Ų114 Ų141%0.0057%0.073CC..  trans-111-15.7172.269.8176.5-5.800114.4R109 M152 P576 F578 L582R109-Q147 HydrophobicContact CB-CB 3.9Å; R109-Q147 HydrophobicContact CB-CG 4.02Å; R109-Q147 HydrophobicContact CG-CB 4.3Å; Q147-M152 WeakPolarHBondContact O-CE 3.12Å; Q147-P576 PolarHBondContact NE2-O 3.03Å; Q147-P576 PolarHBondContact OE1-O 2.86Å; Q147-F578 HydrophobicContact CB-CD2 3.81Å; Q147-F578 HydrophobicContact CG-CD2 3.76Å; Q147-F578 HydrophobicContact CG-CE2 4.07Å; Q147-F578 WeakPolarHBondContact O-CD2 3.34Å; Q147-F578 VanDerWaalsContact OE1-N 3.1Å; Q147-L582 HydrophobicContact CB-CD2 4.33Å
148Y98.1Very high96.6Very high7 Ų715.5 Ų15.53%0.0278%0.079CC..SBendtrans-87.8138.3-180-64.4-72.7000110.6Q108 L150 F151 M152 P459 P462 F578Q108-Y148 HydrophobicContact CB-CE2 3.99Å; Y148-L150 VanDerWaalsContact C-N 3.32Å; Y148-L150 PolarHBondContact O-N 3.44Å; Y148-F151 PolarHBondContact O-N 3.49Å; Y148-M152 PolarHBondContact O-N 3.32Å; Y148-P459 HydrophobicContact CD1-CB 4.26Å; Y148-P459 WeakPolarHBondContact CD1-O 3.4Å; Y148-P459 HydrophobicContact CE1-CB 4.43Å; Y148-P462 HydrophobicContact CD2-CB 4.25Å; Y148-P462 HydrophobicContact CD2-CG 4.42Å; Y148-P462 HydrophobicContact CE1-CB 4.25Å; Y148-P462 HydrophobicContact CE2-CB 3.59Å; Y148-P462 HydrophobicContact CE2-CG 4.2Å; Y148-P462 VanDerWaalsContact CZ-CA 3.5Å; Y148-F578 AromaticContact CD1-CE2 3.99Å; Y148-F578 HydrophobicContact CD1-CE2 3.99Å; Y148-F578 AromaticContact CE1-CE2 3.83Å; Y148-F578 HydrophobicContact CE1-CE2 3.83Å; Y148-F578 HydrophobicContact CE1-CZ 4.18Å
149T97.1Very high96.5Very high1 Ų115.7 Ų15.71%0.0068%0.08CC..Hα-helixtrans-56.4-41.1-165.9-59.60000113.4F151 M152 L153 L458 P459 W460 F583T149-F151 VanDerWaalsContact C-N 3.34Å; T149-F151 PolarHBondContact O-N 3.21Å; T149-M152 PolarHBondContact O-N 3.03Å; T149-M152 VanDerWaalsContact O-N 3.16Å; T149-L153 HydrophobicContact CG2-CD1 4.09Å; T149-L153 HydrophobicContact CG2-CG 4.14Å; T149-L153 WeakPolarHBondContact O-CG 3.4Å; T149-L153 PolarHBondContact O-N 2.81Å; T149-L458 PolarHBondContact OG1-N 3.38Å; T149-L458 PolarHBondContact OG1-O 3.03Å; T149-P459 PolarHBondContact N-O 2.87Å; T149-P459 VanDerWaalsContact N-O 3.1Å; T149-W460 HydrophobicContact CG2-CD2 4.14Å; T149-W460 HydrophobicContact CG2-CG 4.22Å; T149-W460 HydrophobicContact CG2-CZ2 4.22Å; T149-F583 HydrophobicContact CG2-CE1 4.46Å
150L95.7Very high96.3Very high15 Ų1520.8 Ų20.88%0.07910%0.102CC..Hα-helixtrans-56.1-49.2-176.8-177.172.7000111.9Y148 L153 L395 W460 H461Y148-L150 VanDerWaalsContact C-N 3.32Å; Y148-L150 PolarHBondContact O-N 3.44Å; L150-L153 PolarHBondContact O-N 2.87Å; L150-L395 HydrophobicContact CD1-CD1 4.49Å; L150-L395 HydrophobicContact CD2-CD1 3.59Å; L150-W460 HydrophobicContact CB-CE3 4.38Å; L150-W460 WeakPolarHBondContact CB-O 3.31Å; L150-W460 HydrophobicContact CD1-CE3 4.04Å; L150-W460 HydrophobicContact CD1-CZ3 4.19Å; L150-W460 PolarHBondContact N-O 3.23Å; L150-H461 WeakPolarHBondContact CD2-NE2 3.38Å
151F96.1Very high95.9Very high12 Ų1223.4 Ų23.45%0.05312%0.124CC..Hα-helixtrans-73.4-30.3-179-52.2-64.3000112.3F146 Y148 T149 L153 T154 S155 H461 Y520 H522F146-F151 HydrophobicContact CB-CB 3.56Å; F146-F151 HydrophobicContact CB-CD2 4.4Å; F146-F151 HydrophobicContact CB-CG 4.36Å; F146-F151 HydrophobicContact CD1-CB 3.64Å; F146-F151 HydrophobicContact CD1-CD1 4.41Å; F146-F151 AromaticContact CD1-CD2 3.39Å; F146-F151 HydrophobicContact CD1-CD2 3.39Å; F146-F151 HydrophobicContact CD1-CE2 4.15Å; F146-F151 AromaticContact CD1-CG 3.55Å; F146-F151 HydrophobicContact CD1-CG 3.55Å; F146-F151 HydrophobicContact CD2-CB 3.87Å; F146-F151 HydrophobicContact CD2-CG 4.49Å; F146-F151 HydrophobicContact CE1-CB 4.26Å; F146-F151 HydrophobicContact CE1-CD1 4.29Å; F146-F151 AromaticContact CE1-CD2 3.84Å; F146-F151 HydrophobicContact CE1-CD2 3.84Å; F146-F151 HydrophobicContact CE1-CE2 4.26Å; F146-F151 AromaticContact CE1-CG 3.86Å; F146-F151 HydrophobicContact CE1-CG 3.86Å; F146-F151 HydrophobicContact CE2-CB 4.46Å; F146-F151 HydrophobicContact CG-CB 3.42Å; F146-F151 VanDerWaalsContact CG-CB 3.42Å; F146-F151 HydrophobicContact CG-CD2 4.08Å; F146-F151 AromaticContact CG-CG 3.9Å; F146-F151 HydrophobicContact CG-CG 3.9Å; F146-F151 HydrophobicContact CZ-CG 4.45Å; Y148-F151 PolarHBondContact O-N 3.49Å; T149-F151 VanDerWaalsContact C-N 3.34Å; T149-F151 PolarHBondContact O-N 3.21Å; F151-L153 VanDerWaalsContact C-N 3.35Å; F151-T154 PolarHBondContact O-OG1 2.89Å; F151-S155 WeakPolarHBondContact O-CB 3.19Å; F151-S155 PolarHBondContact O-N 2.94Å; F151-S155 PolarHBondContact O-OG 3.33Å; F151-H461 AromaticContact CE2-CD2 3.86Å; F151-H461 AromaticContact CZ-CD2 3.85Å; F151-H461 AromaticContact CZ-NE2 3.73Å; F151-Y520 AromaticContact CE1-CD1 3.65Å; F151-Y520 HydrophobicContact CE1-CD1 3.65Å; F151-Y520 AromaticContact CE1-CE1 3.66Å; F151-Y520 HydrophobicContact CE1-CE1 3.66Å; F151-Y520 HydrophobicContact CE2-CD1 4.43Å; F151-Y520 AromaticContact CZ-CD1 3.6Å; F151-Y520 HydrophobicContact CZ-CD1 3.6Å; F151-Y520 AromaticContact CZ-CE1 3.96Å; F151-Y520 HydrophobicContact CZ-CE1 3.96Å; F151-H522 AromaticContact CE1-CE1 3.89Å; F151-H522 AromaticContact CE1-NE2 3.28Å; F151-H522 VanDerWaalsContact CE1-NE2 3.28Å; F151-H522 WeakPolarHBondContact CE1-NE2 3.4Å; F151-H522 AromaticContact CZ-CD2 3.72Å; F151-H522 AromaticContact CZ-NE2 3.31Å; F151-H522 VanDerWaalsContact CZ-NE2 3.31Å; F151-H522 WeakPolarHBondContact CZ-NE2 3.4Å
152M96.2Very high95.7Very high0 Ų023.4 Ų23.40%012%0.124CC..Hα-helixtrans-66.6-37.1173.6-70.4-166.2-62.600111.4Q147 Y148 T149 S155 K156 G157 L458 L582 F583Q147-M152 WeakPolarHBondContact O-CE 3.12Å; Y148-M152 PolarHBondContact O-N 3.32Å; T149-M152 PolarHBondContact O-N 3.03Å; T149-M152 VanDerWaalsContact O-N 3.16Å; M152-S155 CarbonylContact O-C 3.52Å; M152-S155 PolarHBondContact O-N 3.35Å; M152-K156 CarbonylContact O-C 3.58Å; M152-K156 PolarHBondContact O-N 3.25Å; M152-G157 WeakPolarHBondContact O-CA 3.28Å; M152-G157 PolarHBondContact O-N 3.34Å; M152-L458 HydrophobicContact CE-CD1 4.03Å; M152-L582 HydrophobicContact CE-CD2 4.38Å; M152-L582 HydrophobicContact SD-CD2 3.72Å; M152-F583 HydrophobicContact CB-CE1 3.95Å; M152-F583 HydrophobicContact CB-CE2 3.99Å; M152-F583 HydrophobicContact CB-CZ 3.48Å; M152-F583 VanDerWaalsContact CB-CZ 3.48Å; M152-F583 HydrophobicContact CE-CD1 4.16Å; M152-F583 HydrophobicContact CE-CE1 3.76Å; M152-F583 HydrophobicContact CE-CZ 4.44Å; M152-F583 HydrophobicContact SD-CE1 4.44Å
153L92.9Very high95.6Very high78 Ų7823 Ų2341%0.40812%0.12SC..Hα-helixtrans-60.3-49.8178.5-71.7171.3000111.7T149 L150 F151 S155 K156 W460 F583T149-L153 HydrophobicContact CG2-CD1 4.09Å; T149-L153 HydrophobicContact CG2-CG 4.14Å; T149-L153 WeakPolarHBondContact O-CG 3.4Å; T149-L153 PolarHBondContact O-N 2.81Å; L150-L153 PolarHBondContact O-N 2.87Å; F151-L153 VanDerWaalsContact C-N 3.35Å; L153-S155 VanDerWaalsContact C-N 3.29Å; L153-S155 PolarHBondContact O-N 2.77Å; L153-K156 PolarHBondContact O-N 3.15Å; L153-W460 HydrophobicContact CD1-CH2 3.77Å; L153-W460 HydrophobicContact CD1-CZ2 4.07Å; L153-W460 HydrophobicContact CD1-CZ3 4.14Å; L153-F583 HydrophobicContact CD2-CE2 4.49Å; L153-F583 HydrophobicContact CD2-CZ 3.86Å; L153-F583 HydrophobicContact CG-CZ 4.2Å
154T89.4Confident95.5Very high67 Ų6727 Ų2741%0.41114%0.139SC..Hα-helixtrans-69.1-29.4178.657.60000112.4A69 F151 K156A69-T154 HydrophobicContact CB-CG2 3.97Å; F151-T154 PolarHBondContact O-OG1 2.89Å; T154-K156 VanDerWaalsContact C-N 3.31Å; T154-K156 PolarHBondContact O-N 3Å
155S94.8Very high95.5Very high1 Ų127.2 Ų27.21%0.00714%0.14CC..THydrogen-bonded Turntrans-80.7-4.5175.8-57.10000114.7M66 G144 F151 M152 L153 G157 I159M66-S155 WeakPolarHBondContact CE-OG 3.27Å; G144-S155 PolarHBondContact N-OG 3.16Å; F151-S155 WeakPolarHBondContact O-CB 3.19Å; F151-S155 PolarHBondContact O-N 2.94Å; F151-S155 PolarHBondContact O-OG 3.33Å; M152-S155 CarbonylContact O-C 3.52Å; M152-S155 PolarHBondContact O-N 3.35Å; L153-S155 VanDerWaalsContact C-N 3.29Å; L153-S155 PolarHBondContact O-N 2.77Å; S155-G157 PolarHBondContact O-N 2.86Å; S155-I159 WeakPolarHBondContact O-CD1 3.44Å
156K95.3Very high95.5Very high75 Ų7527.5 Ų27.533%0.32614%0.142SC..THydrogen-bonded Turntrans59.224.4-166.3-56.3-179.2-178.8175.30114.1P64 M152 L153 T154 L585 M586P64-K156 HydrophobicContact CG-CB 4.33Å; P64-K156 HydrophobicContact CG-CD 3.82Å; P64-K156 HydrophobicContact CG-CG 3.87Å; M152-K156 CarbonylContact O-C 3.58Å; M152-K156 PolarHBondContact O-N 3.25Å; L153-K156 PolarHBondContact O-N 3.15Å; T154-K156 VanDerWaalsContact C-N 3.31Å; T154-K156 PolarHBondContact O-N 3Å; K156-L585 HydrophobicContact CB-CB 4.3Å; K156-L585 PolarHBondContact O-N 3.43Å; K156-M586 HydrophobicContact CB-CG 4.03Å; K156-M586 HydrophobicContact CD-CG 4.43Å
157G95.6Very high95.6Very high0 Ų027.8 Ų27.80%014%0.144CC..BIsolated β-bridgetrans119-167.8171.700000114.7G144 M152 S155 F583G144-G157 VanDerWaalsContact CA-O 3.25Å; G144-G157 WeakPolarHBondContact CA-O 3.46Å; M152-G157 WeakPolarHBondContact O-CA 3.28Å; M152-G157 PolarHBondContact O-N 3.34Å; S155-G157 PolarHBondContact O-N 2.86Å; G157-F583 CarbonylContact C-O 3.57Å; G157-F583 WeakPolarHBondContact CA-O 3.42Å
158Y97.1Very high95.6Very high32 Ų3231 Ų3113%0.12516%0.162CC..  trans-87115.7167.2175.9-101.6000109.4R109 E113 G144 K160 V163 L582 F583R109-Y158 VanDerWaalsContact NE-CZ 3.34Å; E113-Y158 PolarHBondContact OE1-OH 2.78Å; G144-Y158 CarbonylContact O-C 3.53Å; G144-Y158 WeakPolarHBondContact O-CA 3.43Å; Y158-K160 HydrophobicContact CE1-CB 4.22Å; Y158-V163 HydrophobicContact CD2-CG2 3.97Å; Y158-V163 HydrophobicContact CE2-CB 4.09Å; Y158-V163 HydrophobicContact CE2-CG1 3.93Å; Y158-V163 HydrophobicContact CE2-CG2 3.42Å; Y158-V163 VanDerWaalsContact CE2-CG2 3.42Å; Y158-L582 HydrophobicContact CD1-CD1 4.12Å; Y158-L582 HydrophobicContact CG-CD1 4.27Å; Y158-F583 PolarHBondContact N-O 3.22Å
159I95.9Very high95.6Very high3 Ų330.7 Ų30.72%0.01516%0.16CC..  trans-109.289.8-172.1-56.9169.2000108.1I63 G144 S155 A161 A162 V163 M586I63-I159 HydrophobicContact CD1-CG2 4.17Å; I63-I159 HydrophobicContact CG2-CD1 3.91Å; G144-I159 PolarHBondContact O-N 3.4Å; S155-I159 WeakPolarHBondContact O-CD1 3.44Å; I159-A161 PolarHBondContact O-N 2.92Å; I159-A161 VanDerWaalsContact O-N 3.11Å; I159-A162 HydrophobicContact CB-CB 4.29Å; I159-A162 HydrophobicContact CG2-CB 4.09Å; I159-A162 PolarHBondContact O-N 2.79Å; I159-V163 WeakPolarHBondContact O-CG2 3.34Å; I159-V163 PolarHBondContact O-N 2.95Å; I159-V163 VanDerWaalsContact O-N 3.16Å; I159-M586 HydrophobicContact CB-CE 4.31Å; I159-M586 HydrophobicContact CD1-CE 3.59Å; I159-M586 HydrophobicContact CD1-CG 4.06Å; I159-M586 HydrophobicContact CD1-SD 3.55Å; I159-M586 VanDerWaalsContact CD1-SD 3.55Å; I159-M586 HydrophobicContact CG1-CE 3.84Å; I159-M586 HydrophobicContact CG1-CG 4.46Å; I159-M586 HydrophobicContact CG1-SD 4.33Å; I159-M586 HydrophobicContact CG2-CE 3.47Å; I159-M586 VanDerWaalsContact CG2-CE 3.47Å
160K93.8Very high95.7Very high121 Ų12130.7 Ų30.753%0.52616%0.16SC..Hα-helixtrans-48.9-42.2-177.3-174.2172.9171177.90113.6Y158 A162 V163 E164Y158-K160 HydrophobicContact CE1-CB 4.22Å; K160-A162 PolarHBondContact O-N 3.4Å; K160-V163 PolarHBondContact O-N 2.88Å; K160-E164 WeakPolarHBondContact CE-OE1 3.45Å; K160-E164 HydrophobicContact CG-CG 4Å; K160-E164 IonicContact NZ-OE1 3.63Å; K160-E164 PolarHBondContact NZ-OE1 3.07Å; K160-E164 PolarHBondContact O-N 3Å
161A91.9Very high95.9Very high55 Ų5530.9 Ų30.946%0.45516%0.162SC..Hα-helixtrans-63.5-22.8178.600000114.6P59 I159 P165P59-A161 WeakPolarHBondContact CD-O 2.91Å; P59-A161 HydrophobicContact CG-CB 4.27Å; I159-A161 PolarHBondContact O-N 2.92Å; I159-A161 VanDerWaalsContact O-N 3.11Å; A161-P165 WeakPolarHBondContact O-CD 3.35Å; A161-P165 WeakPolarHBondContact O-CG 3.47Å
162A92.5Very high96Very high5 Ų533.9 Ų33.94%0.04118%0.175CC..Hα-helixtrans-89.3-27.417200000112.1I63 P142 A143 I159 K160I63-A162 HydrophobicContact CD1-CB 4.16Å; P142-A162 HydrophobicContact CB-CB 4.37Å; A143-A162 WeakPolarHBondContact O-CB 3.41Å; I159-A162 HydrophobicContact CB-CB 4.29Å; I159-A162 HydrophobicContact CG2-CB 4.09Å; I159-A162 PolarHBondContact O-N 2.79Å; K160-A162 PolarHBondContact O-N 3.4Å
163V95.6Very high96.1Very high1 Ų133.9 Ų33.91%0.00618%0.175CC..Hα-helixtrans-79.2-43.6-176.3178.30000112.1E113 G144 Y158 I159 K160 L166 V167E113-V163 VanDerWaalsContact OE2-CG1 3.3Å; E113-V163 WeakPolarHBondContact OE2-CG1 3.18Å; G144-V163 WeakPolarHBondContact O-CG2 3.13Å; Y158-V163 HydrophobicContact CD2-CG2 3.97Å; Y158-V163 HydrophobicContact CE2-CB 4.09Å; Y158-V163 HydrophobicContact CE2-CG1 3.93Å; Y158-V163 HydrophobicContact CE2-CG2 3.42Å; Y158-V163 VanDerWaalsContact CE2-CG2 3.42Å; I159-V163 WeakPolarHBondContact O-CG2 3.34Å; I159-V163 PolarHBondContact O-N 2.95Å; I159-V163 VanDerWaalsContact O-N 3.16Å; K160-V163 PolarHBondContact O-N 2.88Å; V163-L166 WeakPolarHBondContact O-CB 3.36Å; V163-L166 PolarHBondContact O-N 3.34Å; V163-L166 VanDerWaalsContact O-N 3.09Å; V163-V167 HydrophobicContact CG1-CG2 3.93Å; V163-V167 PolarHBondContact O-N 3.4Å
164E96.6Very high96.4Very high85 Ų8530.1 Ų30.140%0.39716%0.155SC..Hα-helixtrans-59.3-48.5-176.8-72.4176.714100112.5K160 L166 V167 N168K160-E164 WeakPolarHBondContact CE-OE1 3.45Å; K160-E164 HydrophobicContact CG-CG 4Å; K160-E164 IonicContact NZ-OE1 3.63Å; K160-E164 PolarHBondContact NZ-OE1 3.07Å; K160-E164 PolarHBondContact O-N 3Å; E164-L166 PolarHBondContact O-N 2.84Å; E164-V167 PolarHBondContact O-N 3.48Å; E164-N168 WeakPolarHBondContact O-CB 3.05Å; E164-N168 PolarHBondContact O-N 2.91Å; E164-N168 PolarHBondContact O-ND2 2.98Å
165P97.3Very high96.9Very high5 Ų528.9 Ų28.93%0.03215%0.146CC..Hα-helixtrans-59.9-35.4174.4-24.335.5000112.8T57 A161 G169 R633T57-P165 WeakPolarHBondContact O-CB 3.37Å; A161-P165 WeakPolarHBondContact O-CD 3.35Å; A161-P165 WeakPolarHBondContact O-CG 3.47Å; P165-G169 WeakPolarHBondContact O-CA 3.19Å; P165-G169 PolarHBondContact O-N 2.85Å; P165-R633 HydrophobicContact CB-CG 4.24Å; P165-R633 WeakPolarHBondContact O-CD 3.35Å
166L98.2Very high97.1Very high9 Ų931.2 Ų31.25%0.04716%0.158CC..Hα-helixtrans-68.3-51.1179.9-176.757.5000111.9C56 V103 L110 Y145 V163 E164 G169 I170C56-L166 HydrophobicContact CB-CD1 3.96Å; V103-L166 HydrophobicContact CG2-CD2 4.18Å; L110-L166 HydrophobicContact CD1-CD2 4Å; L110-L166 HydrophobicContact CD1-CG 3.85Å; L110-L166 HydrophobicContact CD2-CD2 3.63Å; L110-L166 HydrophobicContact CD2-CG 4.01Å; L110-L166 HydrophobicContact CG-CD2 4.45Å; Y145-L166 HydrophobicContact CD1-CD2 4.13Å; Y145-L166 HydrophobicContact CD2-CD2 4.29Å; Y145-L166 HydrophobicContact CG-CD2 3.96Å; V163-L166 WeakPolarHBondContact O-CB 3.36Å; V163-L166 PolarHBondContact O-N 3.34Å; V163-L166 VanDerWaalsContact O-N 3.09Å; E164-L166 PolarHBondContact O-N 2.84Å; L166-G169 PolarHBondContact O-N 2.91Å; L166-I170 HydrophobicContact CD1-CD1 4.13Å; L166-I170 HydrophobicContact CG-CD1 4.35Å; L166-I170 WeakPolarHBondContact O-CG1 3.29Å; L166-I170 PolarHBondContact O-N 2.88Å
167V98.7Very high97.2Very high10 Ų1027.7 Ų27.76%0.06114%0.143CC..Hα-helixtrans-60.2-51.6176.31720000110.2L110 E113 V114 V163 E164 G169 I170 V171L110-V167 HydrophobicContact CD1-CG2 3.62Å; E113-V167 HydrophobicContact CB-CG1 4.36Å; E113-V167 HydrophobicContact CB-CG2 3.9Å; E113-V167 WeakPolarHBondContact OE2-CG2 3.44Å; V114-V167 HydrophobicContact CG2-CB 4.49Å; V114-V167 HydrophobicContact CG2-CG1 4.16Å; V114-V167 HydrophobicContact CG2-CG2 4.49Å; V163-V167 HydrophobicContact CG1-CG2 3.93Å; V163-V167 PolarHBondContact O-N 3.4Å; E164-V167 PolarHBondContact O-N 3.48Å; V167-G169 VanDerWaalsContact C-N 3.28Å; V167-G169 PolarHBondContact O-N 2.79Å; V167-I170 PolarHBondContact O-N 3.45Å; V167-V171 HydrophobicContact CG1-CG2 4.41Å; V167-V171 WeakPolarHBondContact O-CG2 3.5Å; V167-V171 PolarHBondContact O-N 3.22Å
168N98.6Very high97.4Very high69 Ų6930.3 Ų30.337%0.36916%0.155SC..Hα-helixtrans-65.5-34.1-177-66.9-19.9000111.7E164 K172 R633E164-N168 WeakPolarHBondContact O-CB 3.05Å; E164-N168 PolarHBondContact O-N 2.91Å; E164-N168 PolarHBondContact O-ND2 2.98Å; N168-K172 WeakPolarHBondContact O-CB 3.02Å; N168-K172 PolarHBondContact O-N 2.9Å; N168-R633 VanDerWaalsContact CB-NH2 3.26Å; N168-R633 PolarHBondContact O-NH1 3.01Å; N168-R633 VanDerWaalsContact O-NH1 3.16Å
169G98.8Very high97.4Very high0 Ų032.7 Ų32.70%018%0.176CC..Hα-helixtrans-65.7-44175.500000111.8S54 D55 P165 L166 V167 K172 S173 R633S54-G169 VanDerWaalsContact CB-O 3.29Å; S54-G169 WeakPolarHBondContact CB-O 3.48Å; D55-G169 VanDerWaalsContact O-CA 3.23Å; D55-G169 WeakPolarHBondContact O-CA 3.33Å; P165-G169 WeakPolarHBondContact O-CA 3.19Å; P165-G169 PolarHBondContact O-N 2.85Å; L166-G169 PolarHBondContact O-N 2.91Å; V167-G169 VanDerWaalsContact C-N 3.28Å; V167-G169 PolarHBondContact O-N 2.79Å; G169-K172 PolarHBondContact O-N 3.48Å; G169-S173 PolarHBondContact O-N 3.21Å; G169-R633 VanDerWaalsContact N-NH1 3.12Å
170I98.9Very high97.5Very high2 Ų237 Ų371%0.0120%0.2CC..Hα-helixtrans-64.9-44.7175.4-67166.7000111.4S84 V99 L110 V114 L133 L166 V167 K172 S173 I174S84-I170 WeakPolarHBondContact OG-CA 3.42Å; V99-I170 HydrophobicContact CG1-CG2 4.35Å; L110-I170 HydrophobicContact CD1-CD1 4.11Å; L110-I170 HydrophobicContact CD2-CD1 4.09Å; L110-I170 HydrophobicContact CG-CD1 4.28Å; V114-I170 HydrophobicContact CB-CG2 4.5Å; V114-I170 HydrophobicContact CG1-CG2 3.75Å; V114-I170 HydrophobicContact CG2-CB 4.06Å; V114-I170 HydrophobicContact CG2-CD1 4.26Å; V114-I170 HydrophobicContact CG2-CG2 3.89Å; L133-I170 HydrophobicContact CD2-CG2 3.9Å; L166-I170 HydrophobicContact CD1-CD1 4.13Å; L166-I170 HydrophobicContact CG-CD1 4.35Å; L166-I170 WeakPolarHBondContact O-CG1 3.29Å; L166-I170 PolarHBondContact O-N 2.88Å; V167-I170 PolarHBondContact O-N 3.45Å; I170-K172 VanDerWaalsContact C-N 3.31Å; I170-K172 PolarHBondContact O-N 3.41Å; I170-S173 PolarHBondContact O-N 3.44Å; I170-S173 PolarHBondContact O-OG 3.47Å; I170-I174 HydrophobicContact CG2-CD1 4.17Å; I170-I174 WeakPolarHBondContact O-CG1 3.31Å; I170-I174 PolarHBondContact O-N 3.44Å
171V98.9Very high97.6Very high18 Ų1833.2 Ų33.211%0.10918%0.184CC..Hα-helixtrans-63-41.3177.1173.50000110.7V114 A117 L118 V167 I174 D175V114-V171 HydrophobicContact CG1-CG2 4.29Å; A117-V171 HydrophobicContact CB-CG2 3.75Å; L118-V171 HydrophobicContact CD2-CG1 4.4Å; V167-V171 HydrophobicContact CG1-CG2 4.41Å; V167-V171 WeakPolarHBondContact O-CG2 3.5Å; V167-V171 PolarHBondContact O-N 3.22Å; V171-I174 PolarHBondContact O-N 3.37Å; V171-D175 WeakPolarHBondContact O-CB 3.46Å; V171-D175 PolarHBondContact O-N 2.92Å
172K98.9Very high97.8Very high75 Ų7534.4 Ų34.433%0.32618%0.179SC..Hα-helixtrans-68.1-38.3179.4-178.3172.6173.7-177.70112.7S54 N168 G169 I170 I174 D175 I176 D634S54-K172 WeakPolarHBondContact OG-CD 3.29Å; N168-K172 WeakPolarHBondContact O-CB 3.02Å; N168-K172 PolarHBondContact O-N 2.9Å; G169-K172 PolarHBondContact O-N 3.48Å; I170-K172 VanDerWaalsContact C-N 3.31Å; I170-K172 PolarHBondContact O-N 3.41Å; K172-I174 VanDerWaalsContact C-N 3.33Å; K172-I174 PolarHBondContact O-N 2.89Å; K172-D175 WeakPolarHBondContact O-CB 3.35Å; K172-D175 PolarHBondContact O-N 2.88Å; K172-I176 HydrophobicContact CG-CD1 3.97Å; K172-I176 HydrophobicContact CG-CG1 4.43Å; K172-I176 VanDerWaalsContact O-CG1 3.28Å; K172-I176 WeakPolarHBondContact O-CG1 3.31Å; K172-I176 PolarHBondContact O-N 2.9Å; K172-D634 IonicContact NZ-OD1 3.3Å; K172-D634 IonicContact NZ-OD2 2.69Å; K172-D634 PolarHBondContact NZ-OD2 3.23Å
173S98.9Very high98Very high0 Ų037 Ų370%020%0.196CC..Hα-helixtrans-63.7-40.7175.568.20000111.4S84 G169 I170 D175 I176 A177S84-S173 VanDerWaalsContact O-CB 3.23Å; S84-S173 WeakPolarHBondContact O-CB 3.4Å; S84-S173 PolarHBondContact OG-OG 2.91Å; G169-S173 PolarHBondContact O-N 3.21Å; I170-S173 PolarHBondContact O-N 3.44Å; I170-S173 PolarHBondContact O-OG 3.47Å; S173-D175 VanDerWaalsContact C-N 3.35Å; S173-I176 PolarHBondContact O-N 3.49Å; S173-A177 WeakPolarHBondContact O-CB 3.47Å; S173-A177 PolarHBondContact O-N 3.16Å
174I98.9Very high98Very high0 Ų037 Ų370%020%0.196CC..Hα-helixtrans-64.5-40173.4-63.7170.9000110.9A86 I88 V97 V99 L118 Y126 I170 V171 K172 A177 H178A86-I174 HydrophobicContact CB-CB 4.47Å; A86-I174 HydrophobicContact CB-CG1 3.86Å; I88-I174 HydrophobicContact CD1-CG2 4.2Å; V97-I174 HydrophobicContact CG1-CD1 4.17Å; V97-I174 HydrophobicContact CG1-CG1 3.98Å; V97-I174 HydrophobicContact CG1-CG2 4.42Å; V99-I174 HydrophobicContact CG2-CD1 3.88Å; V99-I174 HydrophobicContact CG2-CG1 3.81Å; L118-I174 HydrophobicContact CD1-CD1 3.76Å; L118-I174 HydrophobicContact CD2-CB 4.33Å; L118-I174 HydrophobicContact CD2-CD1 4.16Å; L118-I174 HydrophobicContact CD2-CG2 3.89Å; Y126-I174 HydrophobicContact CD2-CG2 4.44Å; Y126-I174 HydrophobicContact CE2-CG2 4.2Å; I170-I174 HydrophobicContact CG2-CD1 4.17Å; I170-I174 WeakPolarHBondContact O-CG1 3.31Å; I170-I174 PolarHBondContact O-N 3.44Å; V171-I174 PolarHBondContact O-N 3.37Å; K172-I174 VanDerWaalsContact C-N 3.33Å; K172-I174 PolarHBondContact O-N 2.89Å; I174-A177 PolarHBondContact O-N 3.33Å; I174-H178 VanDerWaalsContact O-CB 3.31Å; I174-H178 WeakPolarHBondContact O-CB 3.11Å; I174-H178 PolarHBondContact O-N 2.95Å
175D98.9Very high98Very high40 Ų4034.1 Ų34.121%0.21418%0.181CC..Hα-helixtrans-62.1-44.8177.6-165.950.5000112.8K121 Y122 V171 K172 S173 H178 S179K121-D175 WeakPolarHBondContact CE-OD1 2.96Å; K121-D175 IonicContact NZ-OD1 2.85Å; K121-D175 PolarHBondContact NZ-OD1 2.89Å; K121-D175 IonicContact NZ-OD2 3.01Å; K121-D175 PolarHBondContact NZ-OD2 2.82Å; Y122-D175 PolarHBondContact OH-OD1 3.06Å; V171-D175 WeakPolarHBondContact O-CB 3.46Å; V171-D175 PolarHBondContact O-N 2.92Å; K172-D175 WeakPolarHBondContact O-CB 3.35Å; K172-D175 PolarHBondContact O-N 2.88Å; S173-D175 VanDerWaalsContact C-N 3.35Å; D175-H178 PolarHBondContact O-N 3.36Å; D175-S179 WeakPolarHBondContact O-CB 3.33Å; D175-S179 PolarHBondContact O-N 3.07Å; D175-S179 PolarHBondContact O-OG 3.12Å
176I98.9Very high98.1Very high51 Ų5133.9 Ų33.926%0.26218%0.179SC..Hα-helixtrans-62.6-47.1174.8-67.6164.3000109.6R53 K172 S173 H178 S179 N180R53-I176 WeakPolarHBondContact O-CD1 3.11Å; K172-I176 HydrophobicContact CG-CD1 3.97Å; K172-I176 HydrophobicContact CG-CG1 4.43Å; K172-I176 VanDerWaalsContact O-CG1 3.28Å; K172-I176 WeakPolarHBondContact O-CG1 3.31Å; K172-I176 PolarHBondContact O-N 2.9Å; S173-I176 PolarHBondContact O-N 3.49Å; I176-H178 VanDerWaalsContact C-N 3.34Å; I176-H178 PolarHBondContact O-N 2.96Å; I176-S179 PolarHBondContact O-N 2.94Å; I176-N180 VanDerWaalsContact O-CB 3.32Å; I176-N180 WeakPolarHBondContact O-CB 3.36Å; I176-N180 PolarHBondContact O-N 3.3Å; I176-N180 PolarHBondContact O-ND2 2.62Å
177A98.9Very high98Very high0 Ų035.7 Ų35.70%019%0.186CC..Hα-helixtrans-60.3-44177.800000111.9G50 V51 A86 I88 S173 I174 N180 M181G50-A177 WeakPolarHBondContact CA-O 3.45Å; V51-A177 WeakPolarHBondContact O-CA 3.49Å; A86-A177 HydrophobicContact CB-CB 4.15Å; I88-A177 HydrophobicContact CD1-CB 3.87Å; I88-A177 HydrophobicContact CG1-CB 3.78Å; S173-A177 WeakPolarHBondContact O-CB 3.47Å; S173-A177 PolarHBondContact O-N 3.16Å; I174-A177 PolarHBondContact O-N 3.33Å; A177-N180 PolarHBondContact O-N 3.31Å; A177-M181 WeakPolarHBondContact O-CG 3.16Å; A177-M181 PolarHBondContact O-N 3Å
178H98.8Very high98Very high55 Ų5536.1 Ų36.126%0.25519%0.187SC..Hα-helixtrans-61.2-46.3177.9176.270.7000112.1I88 R95 Y122 Y126 I174 D175 I176 N180 M181I88-H178 HydrophobicContact CD1-CB 3.94Å; R95-H178 PolarHBondContact NH1-CE1 2.81Å; R95-H178 PolarHBondContact NH1-ND1 3.24Å; Y122-H178 AromaticContact CE1-CD2 3.45Å; Y122-H178 VanDerWaalsContact CE1-CD2 3.45Å; Y122-H178 WeakPolarHBondContact CE1-CD2 3.5Å; Y122-H178 AromaticContact CE1-CG 3.98Å; Y122-H178 AromaticContact CE1-NE2 3.55Å; Y122-H178 AromaticContact CZ-CD2 3.83Å; Y122-H178 PolarHBondContact OH-CD2 2.87Å; Y126-H178 AromaticContact CZ-ND1 3.93Å; Y126-H178 WeakPolarHBondContact OH-CB 3.08Å; Y126-H178 PolarHBondContact OH-ND1 3.19Å; I174-H178 VanDerWaalsContact O-CB 3.31Å; I174-H178 WeakPolarHBondContact O-CB 3.11Å; I174-H178 PolarHBondContact O-N 2.95Å; D175-H178 PolarHBondContact O-N 3.36Å; I176-H178 VanDerWaalsContact C-N 3.34Å; I176-H178 PolarHBondContact O-N 2.96Å; H178-N180 VanDerWaalsContact C-N 3.25Å; H178-N180 PolarHBondContact O-N 2.92Å; H178-M181 WeakPolarHBondContact O-CG 3.41Å; H178-M181 PolarHBondContact O-N 3.26Å
179S98.4Very high97.9Very high83 Ų8334.9 Ų34.958%0.5818%0.18SC*.Hα-helixtrans-71.2-23-176.8-55.40000112.8D175 I176D175-S179 WeakPolarHBondContact O-CB 3.33Å; D175-S179 PolarHBondContact O-N 3.07Å; D175-S179 PolarHBondContact O-OG 3.12Å; I176-S179 PolarHBondContact O-N 2.94Å
180N96.1Very high97.9Very high94 Ų9438.8 Ų38.850%0.50319%0.194SC..THydrogen-bonded Turntrans-10518-177.9-65.5-19.8000113.3I176 A177 H178 K182I176-N180 VanDerWaalsContact O-CB 3.32Å; I176-N180 WeakPolarHBondContact O-CB 3.36Å; I176-N180 PolarHBondContact O-N 3.3Å; I176-N180 PolarHBondContact O-ND2 2.62Å; A177-N180 PolarHBondContact O-N 3.31Å; H178-N180 VanDerWaalsContact C-N 3.25Å; H178-N180 PolarHBondContact O-N 2.92Å; N180-K182 PolarHBondContact O-N 3.41Å
181M97.1Very high97.9Very high40 Ų4039.5 Ų39.520%0.19720%0.202CC..  trans-62.3127.6176.7-76.9179.952.200111.5L48 I49 I88 D90 A177 H178L48-M181 HydrophobicContact CB-CE 3.41Å; L48-M181 VanDerWaalsContact CB-CE 3.41Å; L48-M181 HydrophobicContact CD1-CE 3.98Å; L48-M181 HydrophobicContact CG-CE 4.35Å; I49-M181 CarbonylContact O-C 3.35Å; I49-M181 WeakPolarHBondContact O-CA 3.37Å; I88-M181 HydrophobicContact CG2-CG 4.43Å; I88-M181 HydrophobicContact CG2-SD 3.76Å; D90-M181 HydrophobicContact CB-CE 3.82Å; A177-M181 WeakPolarHBondContact O-CG 3.16Å; A177-M181 PolarHBondContact O-N 3Å; H178-M181 WeakPolarHBondContact O-CG 3.41Å; H178-M181 PolarHBondContact O-N 3.26Å
182K95.7Very high97.8Very high80 Ų8042.8 Ų42.835%0.34822%0.217SC..EExtended strand (participates in β ladder)trans-139.5153.6176.550.2-180161.2164.10112.1I49 N180 G184 D231I49-K182 PolarHBondContact N-O 2.92Å; I49-K182 PolarHBondContact O-N 3.45Å; N180-K182 PolarHBondContact O-N 3.41Å; K182-G184 PolarHBondContact O-N 3.47Å; K182-D231 HydrophobicContact CD-CB 3.88Å; K182-D231 HydrophobicContact CG-CB 4.45Å; K182-D231 IonicContact NZ-OD2 2.92Å; K182-D231 PolarHBondContact NZ-OD2 2.84Å
183P96.8Very high97.8Very high61 Ų6139.9 Ų39.940%0.39620%0.204SC..EExtended strand (participates in β ladder)trans-55.5136.4173.1-24.634.4000111.4Y47 L48 L232Y47-P183 CarbonylContact O-C 3.51Å; Y47-P183 VanDerWaalsContact O-CA 3.3Å; Y47-P183 WeakPolarHBondContact O-CA 3.41Å; L48-P183 HydrophobicContact CD2-CB 4.41Å; L48-P183 HydrophobicContact CD2-CG 3.8Å; P183-L232 HydrophobicContact CB-CD1 3.79Å; P183-L232 HydrophobicContact CB-CD2 4.48Å; P183-L232 HydrophobicContact CB-CG 4Å
184G96.3Very high97.7Very high0 Ų044 Ų440%023%0.227CC..EExtended strand (participates in β ladder)trans-168.5176.8-175.200000114.5P46 Y47 K182 T230P46-G184 WeakPolarHBondContact CB-O 3.45Å; Y47-G184 PolarHBondContact N-O 3.39Å; Y47-G184 VanDerWaalsContact N-O 3.1Å; Y47-G184 PolarHBondContact O-N 2.89Å; K182-G184 PolarHBondContact O-N 3.47Å; G184-T230 CarbonylContact C-O 3.5Å; G184-T230 WeakPolarHBondContact CA-O 3.47Å
185R96.8Very high97.4Very high24 Ų2450.3 Ų50.39%0.09126%0.26CS..EExtended strand (participates in β ladder)trans-122.4152180-62.6-174.2-178.7-65.6-13.2111Q43 G44 Y187 T230 E361Q43-R185 VanDerWaalsContact CB-NH2 3.28Å; G44-R185 PolarHBondContact O-NH1 3.38Å; R185-Y187 HydrophobicContact CB-CE2 3.69Å; R185-Y187 WeakPolarHBondContact CD-OH 3.23Å; R185-T230 PolarHBondContact N-O 2.92Å; R185-T230 PolarHBondContact O-N 2.69Å; R185-T230 PolarHBondContact O-OG1 3.28Å; R185-E361 VanDerWaalsContact CD-OE1 3.3Å; R185-E361 WeakPolarHBondContact CD-OE1 3.24Å; R185-E361 IonicContact CZ-OE1 3.64Å; R185-E361 IonicContact NE-OE1 3.68Å; R185-E361 IonicContact NH1-OE1 2.92Å; R185-E361 PolarHBondContact NH1-OE1 2.71Å; R185-E361 IonicContact NH1-OE2 3.37Å
186I97.8Very high97.4Very high0 Ų048.4 Ų48.40%025%0.25CS..EExtended strand (participates in β ladder)trans-118.2132.3179.6-55.9174.6000107.7Y47 I49 I89 L227 K228 F229 E361 V362 V472Y47-I186 HydrophobicContact CD2-CD1 3.76Å; Y47-I186 HydrophobicContact CD2-CG1 3.99Å; Y47-I186 HydrophobicContact CE2-CD1 3.98Å; Y47-I186 HydrophobicContact CE2-CG1 4.27Å; Y47-I186 HydrophobicContact CG-CD1 4.38Å; I49-I186 HydrophobicContact CD1-CD1 4.24Å; I49-I186 HydrophobicContact CD1-CG1 3.63Å; I49-I186 HydrophobicContact CG1-CG1 4.47Å; I89-I186 HydrophobicContact CG1-CD1 3.93Å; I89-I186 HydrophobicContact CG2-CD1 3.8Å; I186-L227 HydrophobicContact CG2-CB 4.39Å; I186-L227 HydrophobicContact CG2-CD2 4.41Å; I186-K228 CarbonylContact C-O 3.57Å; I186-K228 VanDerWaalsContact CA-O 3.31Å; I186-K228 WeakPolarHBondContact CA-O 3.24Å; I186-F229 HydrophobicContact CD1-CD1 4.03Å; I186-F229 HydrophobicContact CD1-CE1 3.77Å; I186-F229 HydrophobicContact CG1-CD1 3.78Å; I186-F229 HydrophobicContact CG1-CE1 3.97Å; I186-F229 HydrophobicContact CG2-CD1 4.45Å; I186-F229 HydrophobicContact CG2-CE1 4.24Å; I186-E361 CarbonylContact O-C 3.48Å; I186-E361 WeakPolarHBondContact O-CA 3.47Å; I186-V362 HydrophobicContact CB-CB 4.12Å; I186-V362 HydrophobicContact CG2-CB 4Å; I186-V362 HydrophobicContact CG2-CG2 4.07Å; I186-V362 PolarHBondContact O-N 2.78Å; I186-V472 HydrophobicContact CD1-CG1 3.59Å
187Y97.3Very high97.3Very high48 Ų4846.3 Ų46.319%0.18824%0.24CC..EExtended strand (participates in β ladder)trans-122.2144.6176.4-59.7-90000109.7R185 L227 K228 T230 E360 E361R185-Y187 HydrophobicContact CB-CE2 3.69Å; R185-Y187 WeakPolarHBondContact CD-OH 3.23Å; Y187-L227 CarbonylContact O-C 3.53Å; Y187-L227 WeakPolarHBondContact O-CA 3.38Å; Y187-K228 HydrophobicContact CD2-CG 4.45Å; Y187-K228 PolarHBondContact N-O 3.33Å; Y187-K228 PolarHBondContact O-N 2.97Å; Y187-T230 HydrophobicContact CD2-CG2 4.31Å; Y187-T230 HydrophobicContact CE2-CG2 4.23Å; Y187-T230 WeakPolarHBondContact CE2-OG1 3.5Å; Y187-E360 CarbonylContact C-O 3.51Å; Y187-E360 VanDerWaalsContact CA-O 3.29Å; Y187-E360 WeakPolarHBondContact CA-O 3.45Å; Y187-E361 HydrophobicContact CD1-CB 3.96Å; Y187-E361 HydrophobicContact CD1-CG 4.37Å; Y187-E361 HydrophobicContact CE1-CB 3.79Å; Y187-E361 HydrophobicContact CE1-CG 4.02Å
188R97.6Very high97.3Very high19 Ų1949.2 Ų49.27%0.07226%0.255CS..EExtended strand (participates in β ladder)trans-112.4151.417569.4179.8-174.6-167.91.6111.7V226 L227 E360 V362 S474 N508 E510R188-V226 VanDerWaalsContact CA-O 3.3Å; R188-V226 WeakPolarHBondContact CA-O 3.32Å; R188-L227 HydrophobicContact CB-CD2 3.66Å; R188-E360 HydrophobicContact CG-CB 4.14Å; R188-E360 HydrophobicContact CG-CG 4.26Å; R188-E360 WeakPolarHBondContact CG-OE2 3.48Å; R188-E360 IonicContact CZ-OE1 3.67Å; R188-E360 VanDerWaalsContact CZ-OE1 3.3Å; R188-E360 IonicContact CZ-OE2 3.36Å; R188-E360 PolarHBondContact N-O 3.09Å; R188-E360 IonicContact NE-OE1 2.65Å; R188-E360 PolarHBondContact NE-OE1 3.25Å; R188-E360 IonicContact NE-OE2 3.36Å; R188-E360 PolarHBondContact NE-OE2 2.93Å; R188-E360 IonicContact NH2-OE1 3.44Å; R188-E360 PolarHBondContact NH2-OE1 2.85Å; R188-E360 IonicContact NH2-OE2 2.85Å; R188-V362 HydrophobicContact CB-CG2 3.75Å; R188-V362 HydrophobicContact CG-CG2 3.9Å; R188-S474 PolarHBondContact NH1-O 3.16Å; R188-S474 PolarHBondContact NH1-OG 3.2Å; R188-N508 PolarHBondContact NH1-O 2.98Å; R188-N508 VanDerWaalsContact NH1-O 3.07Å; R188-N508 PolarHBondContact NH2-O 3.14Å; R188-N508 VanDerWaalsContact NH2-O 3.07Å; R188-E510 VanDerWaalsContact NH1-CB 3.29Å
189N98.1Very high97.3Very high42 Ų4246.9 Ų46.923%0.22525%0.245CC..EExtended strand (participates in β ladder)trans-150.6157.6168.6-155.4-5.5000110.6V226 L354 N357 A358N189-V226 PolarHBondContact N-O 3.47Å; N189-V226 PolarHBondContact O-N 2.9Å; N189-L354 HydrophobicContact CB-CB 4.18Å; N189-L354 HydrophobicContact CB-CD2 4.33Å; N189-L354 WeakPolarHBondContact CB-O 3.4Å; N189-L354 PolarHBondContact ND2-O 3.38Å; N189-N357 PolarHBondContact ND2-O 3.44Å; N189-A358 HydrophobicContact CB-CB 3.88Å
190R98.1Very high97.3Very high82 Ų8243.2 Ų43.231%0.30922%0.218SC..EExtended strand (participates in β ladder)trans-139.8141.5-179.2179.1-175.5-74.5-94.8-13.3110.1D223 V224 L225 L354 E510R190-D223 IonicContact CZ-OD2 2.68Å; R190-D223 VanDerWaalsContact NH1-CB 3.26Å; R190-D223 IonicContact NH1-OD1 2.84Å; R190-D223 IonicContact NH1-OD2 3.61Å; R190-D223 PolarHBondContact NH1-OD2 2.79Å; R190-V224 WeakPolarHBondContact CA-O 3.26Å; R190-L225 HydrophobicContact CB-CD1 4.3Å; R190-L354 VanDerWaalsContact C-CD2 3.43Å; R190-L354 WeakPolarHBondContact O-CD2 3.2Å; R190-E510 IonicContact CZ-OE1 3.96Å; R190-E510 IonicContact NE-OE1 2.9Å; R190-E510 VanDerWaalsContact NH2-CD 3.33Å; R190-E510 IonicContact NH2-OE1 3.22Å; R190-E510 PolarHBondContact NH2-OE1 2.78Å
191G98.2Very high97.4Very high17 Ų1738.8 Ų38.818%0.17520%0.195CC..EExtended strand (participates in β ladder)trans-155.3165.4170.200000112.2D223 V224G191-D223 WeakPolarHBondContact O-CA 3.2Å; G191-V224 PolarHBondContact N-O 3.03Å; G191-V224 PolarHBondContact O-N 2.97Å
192E98.2Very high97.4Very high87 Ų8738.4 Ų38.441%0.40720%0.195SC..EExtended strand (participates in β ladder)trans-89.1140.1177.3-66.5178.1167.800110.1K217 K222 K350E192-K217 VanDerWaalsContact CD-NZ 3.35Å; E192-K217 IonicContact OE1-NZ 2.92Å; E192-K217 PolarHBondContact OE1-NZ 2.8Å; E192-K217 IonicContact OE2-NZ 3.55Å; E192-K217 PolarHBondContact OE2-NZ 2.96Å; E192-K222 CarbonylContact C-O 3.48Å; E192-K222 WeakPolarHBondContact CA-O 3.35Å; E192-K222 HydrophobicContact CB-CB 4.27Å; E192-K222 HydrophobicContact CG-CB 4.44Å; E192-K350 WeakPolarHBondContact O-CE 3.39Å
193L98.3Very high97.5Very high14 Ų1437.5 Ų37.57%0.07319%0.192CC..  trans-121.6110.6172.4175.558.5000110.4K222 V224 F243 N346 I347 K350L193-K222 PolarHBondContact N-O 2.81Å; L193-K222 WeakPolarHBondContact O-CD 3.24Å; L193-V224 HydrophobicContact CB-CG2 3.66Å; L193-V224 HydrophobicContact CD2-CG2 4.16Å; L193-F243 HydrophobicContact CB-CE2 4.11Å; L193-F243 HydrophobicContact CB-CZ 4.27Å; L193-F243 HydrophobicContact CD2-CD1 4.33Å; L193-F243 HydrophobicContact CD2-CE1 3.9Å; L193-F243 HydrophobicContact CD2-CE2 4.29Å; L193-F243 HydrophobicContact CD2-CZ 3.88Å; L193-F243 HydrophobicContact CG-CZ 4.18Å; L193-N346 HydrophobicContact CD1-CB 4.29Å; L193-I347 HydrophobicContact CD2-CB 4.29Å; L193-I347 HydrophobicContact CD2-CG1 3.72Å; L193-K350 HydrophobicContact CB-CB 4.46Å; L193-K350 HydrophobicContact CB-CG 4.19Å; L193-K350 HydrophobicContact CD1-CB 4.2Å; L193-K350 HydrophobicContact CD2-CB 4.43Å
194D96.4Very high97.5Very high88 Ų8834.9 Ų34.947%0.47118%0.175SC..  trans-89.1175174.1-66.1-56.1000112.5S196D194-S196 PolarHBondContact O-N 2.97Å; D194-S196 PolarHBondContact O-OG 2.87Å; D194-S196 VanDerWaalsContact O-OG 3.14Å
195D94Very high97.7Very high132 Ų13235.3 Ų35.371%0.70618%0.177SC*.SBendtrans54.614.3172.3-55.6-36.1000117.1
196S97.6Very high97.7Very high0 Ų038.4 Ų38.40%019%0.193CC..SBendtrans-122.95.6179.8-51.30000112.9D194 N346D194-S196 PolarHBondContact O-N 2.97Å; D194-S196 PolarHBondContact O-OG 2.87Å; D194-S196 VanDerWaalsContact O-OG 3.14Å; S196-N346 WeakPolarHBondContact OG-CB 3.44Å; S196-N346 PolarHBondContact OG-ND2 3.36Å
197S97.4Very high97.8Very high7 Ų742 Ų425%0.04921%0.213CC..  trans-156.7144.4178.860.80000112.8K222 T297S197-K222 PolarHBondContact O-NZ 2.87Å; S197-K222 PolarHBondContact OG-NZ 3.22Å; S197-T297 CarbonylContact C-O 3.09Å; S197-T297 WeakPolarHBondContact CA-O 3.3Å
198L98.1Very high97.8Very high60 Ų6039.9 Ų39.931%0.31420%0.204SC..EExtended strand (participates in β ladder)trans-133.9147.4174.5-174.395.3000109.3V296 T297L198-V296 CarbonylContact O-C 3.45Å; L198-V296 WeakPolarHBondContact O-CA 3.48Å; L198-T297 HydrophobicContact CB-CG2 3.91Å; L198-T297 HydrophobicContact CD2-CG2 4.15Å; L198-T297 PolarHBondContact N-O 3.06Å; L198-T297 WeakPolarHBondContact O-CG2 3.36Å; L198-T297 PolarHBondContact O-N 3.42Å
199N98.6Very high97.9Very high6 Ų641.7 Ų41.73%0.03222%0.219CC..EExtended strand (participates in β ladder)trans-77.6126171.3-167.2-56.4000109.9S201 P202 N219 T220 D295N199-S201 WeakPolarHBondContact OD1-CA 3.39Å; N199-S201 PolarHBondContact OD1-N 2.84Å; N199-S201 PolarHBondContact OD1-O 3.1Å; N199-P202 VanDerWaalsContact OD1-N 3.11Å; N199-N219 HydrophobicContact CB-CB 4.36Å; N199-N219 PolarHBondContact ND2-O 3.24Å; N199-T220 HydrophobicContact CB-CG2 3.84Å; N199-T220 VanDerWaalsContact N-CG2 3.35Å; N199-D295 CarbonylContact C-O 3.58Å; N199-D295 VanDerWaalsContact CA-O 3.25Å; N199-D295 WeakPolarHBondContact CA-O 3.35Å; N199-D295 PolarHBondContact ND2-OD2 2.58Å; N199-D295 PolarHBondContact OD1-O 3.01Å
200R98.3Very high97.9Very high7 Ų746.2 Ų46.23%0.02624%0.236CC..SBendtrans-91.2-7.3-179.173.6-176.1-174.8-170.6-6.2114.8P202 H246 G294 D295 T297 I404 D405 Y523 R534 E536R200-P202 VanDerWaalsContact C-CD 3.41Å; R200-H246 VanDerWaalsContact CZ-CE1 3.46Å; R200-H246 PolarHBondContact NH1-CE1 3.42Å; R200-H246 PolarHBondContact NH2-CE1 2.81Å; R200-H246 PolarHBondContact NH2-NE2 2.97Å; R200-G294 PolarHBondContact NE-O 2.96Å; R200-G294 PolarHBondContact NH2-O 3.39Å; R200-D295 PolarHBondContact N-O 2.85Å; R200-T297 HydrophobicContact CB-CG2 3.93Å; R200-I404 HydrophobicContact CB-CD1 3.57Å; R200-I404 HydrophobicContact CB-CG1 3.89Å; R200-D405 WeakPolarHBondContact CD-OD2 3.42Å; R200-D405 IonicContact CZ-OD2 3.82Å; R200-D405 IonicContact NE-OD2 3Å; R200-D405 IonicContact NH1-OD2 2.71Å; R200-D405 PolarHBondContact NH1-OD2 2.94Å; R200-Y523 VanDerWaalsContact NH2-CZ 3.34Å; R200-Y523 PolarHBondContact NH2-OH 3.11Å; R200-R534 PolarHBondContact O-NH2 3.27Å; R200-E536 IonicContact CZ-OE1 3.6Å; R200-E536 IonicContact NE-OE1 2.72Å; R200-E536 PolarHBondContact NE-OE1 2.94Å; R200-E536 IonicContact NH2-OE1 3.94Å
201S98.4Very high97.9Very high1 Ų147.9 Ų47.91%0.00725%0.251CS..  trans-132.353.4174.9-75.40000111.3N199 H203 S204 Y205 R534 E536N199-S201 WeakPolarHBondContact OD1-CA 3.39Å; N199-S201 PolarHBondContact OD1-N 2.84Å; N199-S201 PolarHBondContact OD1-O 3.1Å; S201-H203 PolarHBondContact O-N 3.41Å; S201-S204 WeakPolarHBondContact O-CB 3.08Å; S201-S204 PolarHBondContact O-N 3.37Å; S201-Y205 PolarHBondContact O-N 3.44Å; S201-R534 PolarHBondContact OG-NE 2.79Å; S201-E536 WeakPolarHBondContact CB-OE2 3.23Å; S201-E536 VanDerWaalsContact OG-CD 3.31Å; S201-E536 PolarHBondContact OG-OE1 3.46Å; S201-E536 PolarHBondContact OG-OE2 3.2Å
202P97.8Very high97.9Very high32 Ų3248.4 Ų48.421%0.20825%0.249CC..Hα-helixtrans-62.5-31.5-170.826-35.6000112.5N199 R200 S204 Y205 M206 Y314N199-P202 VanDerWaalsContact OD1-N 3.11Å; R200-P202 VanDerWaalsContact C-CD 3.41Å; P202-S204 PolarHBondContact O-N 3.11Å; P202-Y205 PolarHBondContact O-N 2.85Å; P202-M206 VanDerWaalsContact O-CG 3.22Å; P202-M206 WeakPolarHBondContact O-CG 3.44Å; P202-M206 PolarHBondContact O-N 2.79Å; P202-Y314 HydrophobicContact CB-CE2 4.35Å; P202-Y314 HydrophobicContact CG-CE2 3.71Å
203H96.6Very high98Very high60 Ų6046.7 Ų46.728%0.27824%0.239SC..Hα-helixtrans-61.2-43.3174.6-176.6-105.5000112.3S201 M206 N207 Y314 L315 V532S201-H203 PolarHBondContact O-N 3.41Å; H203-M206 PolarHBondContact O-N 2.97Å; H203-N207 PolarHBondContact O-N 3.46Å; H203-Y314 HydrophobicContact CB-CD1 4.33Å; H203-Y314 HydrophobicContact CB-CE1 3.7Å; H203-Y314 AromaticContact CD2-CE1 3.65Å; H203-Y314 PolarHBondContact N-OH 3.13Å; H203-L315 HydrophobicContact CB-CD2 4.22Å; H203-L315 WeakPolarHBondContact CD2-CD2 3.41Å; H203-L315 WeakPolarHBondContact CE1-CD2 3.31Å; H203-L315 WeakPolarHBondContact ND1-CD2 3.45Å; H203-L315 VanDerWaalsContact NE2-CD2 3.33Å; H203-L315 WeakPolarHBondContact NE2-CD2 3.39Å; H203-V532 WeakPolarHBondContact ND1-CG1 3.33Å
204S98.6Very high98Very high7 Ų752.6 Ų52.65%0.04926%0.264CS..Hα-helixtrans-62.8-44.8175.9-63.90000111.4S201 P202 M206 N207 E529 R534S201-S204 WeakPolarHBondContact O-CB 3.08Å; S201-S204 PolarHBondContact O-N 3.37Å; P202-S204 PolarHBondContact O-N 3.11Å; S204-M206 PolarHBondContact O-N 3.46Å; S204-N207 VanDerWaalsContact O-CB 3.3Å; S204-N207 WeakPolarHBondContact O-CB 3.42Å; S204-N207 PolarHBondContact O-N 2.8Å; S204-E529 WeakPolarHBondContact O-CG 3.45Å; S204-R534 WeakPolarHBondContact OG-CD 3.46Å
205Y98.8Very high98Very high9 Ų955.2 Ų55.24%0.03527%0.267CS..Hα-helixtrans-56.1-41.5175.4176.2-89.8000111.7S201 P202 N207 N208 R213 S218 N219 T486 M487 R490S201-Y205 PolarHBondContact O-N 3.44Å; P202-Y205 PolarHBondContact O-N 2.85Å; Y205-N207 PolarHBondContact O-N 3.35Å; Y205-N208 WeakPolarHBondContact O-CB 3.29Å; Y205-N208 PolarHBondContact O-N 3.48Å; Y205-N208 VanDerWaalsContact O-N 3.12Å; Y205-N208 PolarHBondContact O-ND2 3.06Å; Y205-R213 HydrophobicContact CE1-CG 3.99Å; Y205-R213 WeakPolarHBondContact O-CD 3.23Å; Y205-S218 PolarHBondContact OH-O 3.35Å; Y205-N219 HydrophobicContact CD1-CB 3.4Å; Y205-N219 HydrophobicContact CD2-CB 4.03Å; Y205-N219 HydrophobicContact CE1-CB 3.46Å; Y205-N219 VanDerWaalsContact CE1-CB 3.46Å; Y205-N219 HydrophobicContact CE2-CB 4.08Å; Y205-N219 HydrophobicContact CG-CB 3.71Å; Y205-T486 HydrophobicContact CE2-CG2 4.27Å; Y205-M487 HydrophobicContact CE2-CB 4.46Å; Y205-M487 HydrophobicContact CE2-CE 3.7Å; Y205-R490 PolarHBondContact OH-NH1 3Å
206M98.4Very high98.2Very high89 Ų8951.3 Ų51.344%0.43824%0.243SC..Hα-helixtrans-65.6-18.3-179.5-69.5-63.3-72.500113.8P202 H203 S204 N208 R213P202-M206 VanDerWaalsContact O-CG 3.22Å; P202-M206 WeakPolarHBondContact O-CG 3.44Å; P202-M206 PolarHBondContact O-N 2.79Å; H203-M206 PolarHBondContact O-N 2.97Å; S204-M206 PolarHBondContact O-N 3.46Å; M206-N208 VanDerWaalsContact C-N 3.29Å; M206-R213 PolarHBondContact O-NE 3.09Å; M206-R213 PolarHBondContact O-NH2 2.81Å; M206-R213 VanDerWaalsContact O-NH2 3.08Å; M206-R213 PolarHBondContact SD-NH1 2.8Å
207N98.3Very high98.2Very high76 Ų7659.7 Ų59.741%0.40628%0.28SS..THydrogen-bonded Turntrans-74.7-17.9175.5-153.942.2000113.1H203 S204 Y205 E528 V532H203-N207 PolarHBondContact O-N 3.46Å; S204-N207 VanDerWaalsContact O-CB 3.3Å; S204-N207 WeakPolarHBondContact O-CB 3.42Å; S204-N207 PolarHBondContact O-N 2.8Å; Y205-N207 PolarHBondContact O-N 3.35Å; N207-E528 PolarHBondContact ND2-O 2.9Å; N207-E528 WeakPolarHBondContact O-CB 3.4Å; N207-V532 HydrophobicContact CB-CG2 3.91Å
208N98.9Very high98.2Very high2 Ų261 Ų611%0.01129%0.289CS..SBendtrans-61.4151.1170.7-65.7-63.3000111.2Y205 M206 K210 R213 M487 T526 E529Y205-N208 WeakPolarHBondContact O-CB 3.29Å; Y205-N208 PolarHBondContact O-N 3.48Å; Y205-N208 VanDerWaalsContact O-N 3.12Å; Y205-N208 PolarHBondContact O-ND2 3.06Å; M206-N208 VanDerWaalsContact C-N 3.29Å; N208-K210 PolarHBondContact O-N 3Å; N208-R213 HydrophobicContact CB-CG 4Å; N208-R213 PolarHBondContact O-NE 2.95Å; N208-M487 HydrophobicContact CB-CG 4.38Å; N208-T526 WeakPolarHBondContact OD1-CB 3.23Å; N208-T526 WeakPolarHBondContact OD1-CG2 3.41Å; N208-T526 PolarHBondContact OD1-OG1 2.88Å; N208-E529 PolarHBondContact ND2-OE1 3.11Å
209P98.8Very high98.2Very high57 Ų5760.6 Ų60.637%0.3729%0.287SS..  trans-51.3132.5-177.3-28.335.8000112.8D211 E212 R213 E528P209-D211 VanDerWaalsContact C-N 3.26Å; P209-D211 PolarHBondContact O-N 2.91Å; P209-E212 HydrophobicContact CB-CB 4.25Å; P209-E212 WeakPolarHBondContact O-CB 3.43Å; P209-E212 PolarHBondContact O-N 3.07Å; P209-E212 VanDerWaalsContact O-N 3.07Å; P209-R213 PolarHBondContact O-N 2.88Å; P209-E528 WeakPolarHBondContact CD-OE1 3.48Å
210K98.4Very high98.2Very high137 Ų13760.4 Ų60.460%0.59629%0.286SS*.Hα-helixtrans-56-40.6-175.2-174178.6-177.2176.80112.5N208 R213 K214N208-K210 PolarHBondContact O-N 3Å; K210-R213 PolarHBondContact O-N 2.99Å; K210-K214 WeakPolarHBondContact O-CG 3.22Å; K210-K214 PolarHBondContact O-N 2.81Å; K210-K214 VanDerWaalsContact O-N 3.09Å
211D98.4Very high98.2Very high117 Ų11760.6 Ų60.663%0.62629%0.287SS*.Hα-helixtrans-72.8-29.7-178.3-64-30.7000112.6P209 K214P209-D211 VanDerWaalsContact C-N 3.26Å; P209-D211 PolarHBondContact O-N 2.91Å; D211-K214 IonicContact OD1-NZ 2.99Å; D211-K214 PolarHBondContact OD1-NZ 2.76Å
212E98.7Very high98.2Very high28 Ų2861.8 Ų61.813%0.13129%0.292CS..Hα-helixtrans-68.2-46.5170-177-179-139.500110.7P209 K214 R215 Y216 M487 R491P209-E212 HydrophobicContact CB-CB 4.25Å; P209-E212 WeakPolarHBondContact O-CB 3.43Å; P209-E212 PolarHBondContact O-N 3.07Å; P209-E212 VanDerWaalsContact O-N 3.07Å; E212-K214 VanDerWaalsContact C-N 3.3Å; E212-K214 PolarHBondContact O-N 2.91Å; E212-R215 VanDerWaalsContact O-CB 3.25Å; E212-R215 WeakPolarHBondContact O-CB 3.34Å; E212-R215 WeakPolarHBondContact O-CG 3.47Å; E212-R215 PolarHBondContact O-N 2.6Å; E212-Y216 HydrophobicContact CG-CE2 4.21Å; E212-Y216 WeakPolarHBondContact O-CD2 3.28Å; E212-Y216 WeakPolarHBondContact O-CE2 3.21Å; E212-M487 VanDerWaalsContact CD-SD 3.58Å; E212-M487 HydrophobicContact CG-CE 4.16Å; E212-M487 HydrophobicContact CG-SD 3.92Å; E212-R491 WeakPolarHBondContact OE1-CG 3.49Å; E212-R491 IonicContact OE1-CZ 3.2Å; E212-R491 IonicContact OE1-NE 3.57Å; E212-R491 PolarHBondContact OE1-NE 2.91Å; E212-R491 IonicContact OE1-NH2 3.96Å; E212-R491 IonicContact OE2-CZ 3.98Å; E212-R491 IonicContact OE2-NE 2.86Å; E212-R491 PolarHBondContact OE2-NE 2.9Å; E212-R491 IonicContact OE2-NH2 3.65Å; E212-R491 PolarHBondContact OE2-NH2 2.87Å
213R98.4Very high98.2Very high51 Ų5162.9 Ų62.919%0.19230%0.297CS..Hα-helixtrans-60.3-37.4-179.7-68.7-170.9-68.8119.3-15.1113.1Y205 M206 N208 P209 K210 R215 Y216 M487Y205-R213 HydrophobicContact CE1-CG 3.99Å; Y205-R213 WeakPolarHBondContact O-CD 3.23Å; M206-R213 PolarHBondContact O-NE 3.09Å; M206-R213 PolarHBondContact O-NH2 2.81Å; M206-R213 VanDerWaalsContact O-NH2 3.08Å; M206-R213 PolarHBondContact SD-NH1 2.8Å; N208-R213 HydrophobicContact CB-CG 4Å; N208-R213 PolarHBondContact O-NE 2.95Å; P209-R213 PolarHBondContact O-N 2.88Å; K210-R213 PolarHBondContact O-N 2.99Å; R213-R215 PolarHBondContact O-N 2.58Å; R213-R215 VanDerWaalsContact O-N 3.15Å; R213-Y216 PolarHBondContact O-N 2.98Å; R213-Y216 VanDerWaalsContact O-N 3.12Å; R213-M487 HydrophobicContact CG-CE 4.15Å
214K98.3Very high98.3Very high139 Ų13960 Ų6060%0.60428%0.283SS*.THydrogen-bonded Turntrans-62-15.9176.9-76.9173-177.6166.30114.1K210 D211 E212 Y216K210-K214 WeakPolarHBondContact O-CG 3.22Å; K210-K214 PolarHBondContact O-N 2.81Å; K210-K214 VanDerWaalsContact O-N 3.09Å; D211-K214 IonicContact OD1-NZ 2.99Å; D211-K214 PolarHBondContact OD1-NZ 2.76Å; E212-K214 VanDerWaalsContact C-N 3.3Å; E212-K214 PolarHBondContact O-N 2.91Å; K214-Y216 PolarHBondContact O-N 2.87Å
215R98.4Very high98.3Very high142 Ų14259.9 Ų59.954%0.53628%0.282SS..THydrogen-bonded Turntrans-74-13.9176.1-58.4166.163.4-157.6-5.2112.6E212 R213 E494E212-R215 VanDerWaalsContact O-CB 3.25Å; E212-R215 WeakPolarHBondContact O-CB 3.34Å; E212-R215 WeakPolarHBondContact O-CG 3.47Å; E212-R215 PolarHBondContact O-N 2.6Å; R213-R215 PolarHBondContact O-N 2.58Å; R213-R215 VanDerWaalsContact O-N 3.15Å; R215-E494 IonicContact CZ-OE1 3.35Å; R215-E494 IonicContact CZ-OE2 3.89Å; R215-E494 IonicContact NH1-OE1 3.55Å; R215-E494 IonicContact NH1-OE2 2.73Å; R215-E494 PolarHBondContact NH1-OE2 2.82Å; R215-E494 IonicContact NH2-OE1 3.56Å; R215-E494 PolarHBondContact NH2-OE1 2.93Å; R215-E494 IonicContact NH2-OE2 3.91Å; R215-E494 PolarHBondContact NH2-OE2 3.4Å
216Y98Very high98.3Very high50 Ų5059.5 Ų59.520%0.19628%0.281CS..SBendtrans-122.5144.6-174.4-51.8-81.1000110.9E212 R213 K214 M487 R490 E494E212-Y216 HydrophobicContact CG-CE2 4.21Å; E212-Y216 WeakPolarHBondContact O-CD2 3.28Å; E212-Y216 WeakPolarHBondContact O-CE2 3.21Å; R213-Y216 PolarHBondContact O-N 2.98Å; R213-Y216 VanDerWaalsContact O-N 3.12Å; K214-Y216 PolarHBondContact O-N 2.87Å; Y216-M487 HydrophobicContact CD2-CE 3.93Å; Y216-M487 HydrophobicContact CD2-SD 4.45Å; Y216-M487 HydrophobicContact CE2-CE 3.85Å; Y216-M487 HydrophobicContact CE2-SD 3.81Å; Y216-R490 VanDerWaalsContact CB-NH1 3.31Å; Y216-R490 HydrophobicContact CD1-CG 4.47Å; Y216-R490 HydrophobicContact CE1-CB 4.28Å; Y216-R490 HydrophobicContact CE1-CG 3.89Å; Y216-R490 VanDerWaalsContact CG-NH1 3.28Å; Y216-E494 PolarHBondContact OH-OE1 3.4Å
217K96.7Very high98.3Very high177 Ų17755.5 Ų55.577%0.7726%0.261SS*.SBendtrans-73.9-26.7179.8-59.4175.1-172.5161.70113.4E192E192-K217 VanDerWaalsContact CD-NZ 3.35Å; E192-K217 IonicContact OE1-NZ 2.92Å; E192-K217 PolarHBondContact OE1-NZ 2.8Å; E192-K217 IonicContact OE2-NZ 3.55Å; E192-K217 PolarHBondContact OE2-NZ 2.96Å
218S97.5Very high98.3Very high35 Ų3553.6 Ų53.625%0.24525%0.249CC..  trans-141.1160.1-170.8-1730000112.5Y205 T220 R490Y205-S218 PolarHBondContact OH-O 3.35Å; S218-T220 VanDerWaalsContact C-N 3.27Å; S218-T220 PolarHBondContact OG-N 3.16Å; S218-T220 PolarHBondContact OG-OG1 2.77Å; S218-R490 PolarHBondContact O-NH1 2.95Å; S218-R490 PolarHBondContact O-NH2 2.94Å
219N98.2Very high98.2Very high50 Ų5053.5 Ų53.527%0.26725%0.249SC..SBendtrans-87.48.8172.666.3-2.5000113.5N199 Y205 T486N199-N219 HydrophobicContact CB-CB 4.36Å; N199-N219 PolarHBondContact ND2-O 3.24Å; Y205-N219 HydrophobicContact CD1-CB 3.4Å; Y205-N219 HydrophobicContact CD2-CB 4.03Å; Y205-N219 HydrophobicContact CE1-CB 3.46Å; Y205-N219 VanDerWaalsContact CE1-CB 3.46Å; Y205-N219 HydrophobicContact CE2-CB 4.08Å; Y205-N219 HydrophobicContact CG-CB 3.71Å; N219-T486 PolarHBondContact O-OG1 2.87Å
220T98.4Very high98.1Very high2 Ų251 Ų511%0.01223%0.232CC..SBendtrans-128.2155.9167.249.80000108.4N199 S218 K222 V296 R490N199-T220 HydrophobicContact CB-CG2 3.84Å; N199-T220 VanDerWaalsContact N-CG2 3.35Å; S218-T220 VanDerWaalsContact C-N 3.27Å; S218-T220 PolarHBondContact OG-N 3.16Å; S218-T220 PolarHBondContact OG-OG1 2.77Å; T220-K222 PolarHBondContact O-N 2.84Å; T220-K222 WeakPolarHBondContact OG1-CE 3.32Å; T220-K222 PolarHBondContact OG1-NZ 3.4Å; T220-V296 HydrophobicContact CG2-CG1 3.83Å; T220-V296 HydrophobicContact CG2-CG2 4.15Å; T220-R490 PolarHBondContact O-NH2 3.05Å
221D98.1Very high97.8Very high11 Ų1145.5 Ų45.56%0.05921%0.21CC..  trans-83.9111.4170.6-73.6-32.4000110.4D223 A244 N292 R490 R493D221-D223 VanDerWaalsContact C-N 3.32Å; D221-A244 HydrophobicContact CB-CB 4.19Å; D221-N292 PolarHBondContact OD2-ND2 2.82Å; D221-N292 PolarHBondContact OD2-OD1 2.79Å; D221-R490 IonicContact OD1-CZ 3.84Å; D221-R490 IonicContact OD1-NE 2.88Å; D221-R490 PolarHBondContact OD1-NE 3.35Å; D221-R490 IonicContact OD1-NH2 3.68Å; D221-R490 PolarHBondContact OD1-NH2 3.14Å; D221-R490 IonicContact OD2-NE 3.9Å; D221-R493 VanDerWaalsContact CG-NH2 3.27Å; D221-R493 IonicContact OD1-NH2 3.09Å; D221-R493 IonicContact OD2-CZ 3.64Å; D221-R493 IonicContact OD2-NH1 2.62Å; D221-R493 IonicContact OD2-NH2 3.34Å; D221-R493 PolarHBondContact OD2-NH2 2.9Å
222K98.3Very high97.3Very high26 Ų2644.7 Ų44.711%0.11321%0.205CC..  trans-83.9-11179.5-59.4-59.7-172.8-176.10112.8E192 L193 S197 T220 V224E192-K222 CarbonylContact C-O 3.48Å; E192-K222 WeakPolarHBondContact CA-O 3.35Å; E192-K222 HydrophobicContact CB-CB 4.27Å; E192-K222 HydrophobicContact CG-CB 4.44Å; L193-K222 PolarHBondContact N-O 2.81Å; L193-K222 WeakPolarHBondContact O-CD 3.24Å; S197-K222 PolarHBondContact O-NZ 2.87Å; S197-K222 PolarHBondContact OG-NZ 3.22Å; T220-K222 PolarHBondContact O-N 2.84Å; T220-K222 WeakPolarHBondContact OG1-CE 3.32Å; T220-K222 PolarHBondContact OG1-NZ 3.4Å; K222-V224 PolarHBondContact O-N 2.85Å
223D97.8Very high96.4Very high55 Ų5550.4 Ų50.429%0.29424%0.236SC..EExtended strand (participates in β ladder)trans-69.7124.2-176.9-70.5-31.8000112.1R190 G191 D221R190-D223 IonicContact CZ-OD2 2.68Å; R190-D223 VanDerWaalsContact NH1-CB 3.26Å; R190-D223 IonicContact NH1-OD1 2.84Å; R190-D223 IonicContact NH1-OD2 3.61Å; R190-D223 PolarHBondContact NH1-OD2 2.79Å; G191-D223 WeakPolarHBondContact O-CA 3.2Å; D221-D223 VanDerWaalsContact C-N 3.32Å
224V98.6Very high95.1Very high0 Ų050 Ų500%025%0.248CC..EExtended strand (participates in β ladder)trans-100.3123.8163-177.90000107.5R190 G191 L193 K222 V226 S241 W242 F243 K350 L354R190-V224 WeakPolarHBondContact CA-O 3.26Å; G191-V224 PolarHBondContact N-O 3.03Å; G191-V224 PolarHBondContact O-N 2.97Å; L193-V224 HydrophobicContact CB-CG2 3.66Å; L193-V224 HydrophobicContact CD2-CG2 4.16Å; K222-V224 PolarHBondContact O-N 2.85Å; V224-V226 HydrophobicContact CG1-CG2 4.43Å; V224-S241 WeakPolarHBondContact CG1-OG 3.42Å; V224-W242 WeakPolarHBondContact CA-O 3.22Å; V224-F243 HydrophobicContact CG2-CB 4.23Å; V224-F243 HydrophobicContact CG2-CD2 3.55Å; V224-F243 HydrophobicContact CG2-CE2 4.11Å; V224-F243 HydrophobicContact CG2-CG 4.01Å; V224-K350 HydrophobicContact CB-CG 4.06Å; V224-K350 HydrophobicContact CG1-CG 4.4Å; V224-K350 HydrophobicContact CG2-CG 3.89Å; V224-L354 HydrophobicContact CB-CD1 3.91Å; V224-L354 HydrophobicContact CG1-CD1 3.86Å; V224-L354 WeakPolarHBondContact O-CD1 3.45Å
225L98.4Very high93.7Very high5 Ų549.3 Ų49.33%0.02625%0.25CS..EExtended strand (participates in β ladder)trans-108.5132171.2-170.6111.7000109.8R190 L227 S241 W242 E510 V512R190-L225 HydrophobicContact CB-CD1 4.3Å; L225-L227 HydrophobicContact CD2-CD2 4.36Å; L225-L227 HydrophobicContact CD2-CG 4.45Å; L225-S241 CarbonylContact O-C 3.53Å; L225-S241 VanDerWaalsContact O-CA 3.24Å; L225-S241 WeakPolarHBondContact O-CA 3.48Å; L225-W242 HydrophobicContact CD2-CE3 4.08Å; L225-W242 HydrophobicContact CD2-CZ3 4.28Å; L225-W242 PolarHBondContact N-O 3.02Å; L225-W242 VanDerWaalsContact N-O 3.15Å; L225-W242 PolarHBondContact O-N 3.32Å; L225-E510 HydrophobicContact CD1-CG 3.62Å; L225-V512 HydrophobicContact CB-CG1 4.08Å; L225-V512 HydrophobicContact CD1-CG1 4.41Å; L225-V512 HydrophobicContact CD2-CG1 3.43Å; L225-V512 VanDerWaalsContact CD2-CG1 3.43Å; L225-V512 HydrophobicContact CG-CG1 4.13Å
226V98.6Very high93.2Very high0 Ų043.8 Ų43.80%024%0.238CC..EExtended strand (participates in β ladder)trans-115.2135.3175.6167.10000110.5R188 N189 V224 M239 I240 A351 L354 Y355R188-V226 VanDerWaalsContact CA-O 3.3Å; R188-V226 WeakPolarHBondContact CA-O 3.32Å; N189-V226 PolarHBondContact N-O 3.47Å; N189-V226 PolarHBondContact O-N 2.9Å; V224-V226 HydrophobicContact CG1-CG2 4.43Å; V226-M239 HydrophobicContact CG1-CG 3.59Å; V226-M239 HydrophobicContact CG1-SD 3.67Å; V226-M239 HydrophobicContact CG2-SD 4.02Å; V226-I240 CarbonylContact C-O 3.44Å; V226-I240 WeakPolarHBondContact CA-O 3.13Å; V226-A351 HydrophobicContact CG2-CB 4.13Å; V226-L354 HydrophobicContact CB-CB 4.14Å; V226-L354 HydrophobicContact CG2-CB 3.86Å; V226-L354 HydrophobicContact CG2-CD1 4.18Å; V226-Y355 HydrophobicContact CG1-CD2 4.39Å
227L98.6Very high93.1Very high6 Ų641.9 Ų41.93%0.03123%0.231CC..EExtended strand (participates in β ladder)trans-106.5118157.5-62.8-177.1000109.1I186 Y187 R188 L225 F229 M239 I240 W242 V362 V475I186-L227 HydrophobicContact CG2-CB 4.39Å; I186-L227 HydrophobicContact CG2-CD2 4.41Å; Y187-L227 CarbonylContact O-C 3.53Å; Y187-L227 WeakPolarHBondContact O-CA 3.38Å; R188-L227 HydrophobicContact CB-CD2 3.66Å; L225-L227 HydrophobicContact CD2-CD2 4.36Å; L225-L227 HydrophobicContact CD2-CG 4.45Å; L227-F229 HydrophobicContact CB-CE2 3.87Å; L227-F229 HydrophobicContact CB-CZ 4.01Å; L227-F229 HydrophobicContact CD1-CZ 4.4Å; L227-F229 WeakPolarHBondContact O-CE2 3.28Å; L227-M239 CarbonylContact O-C 3.6Å; L227-M239 VanDerWaalsContact O-CA 3.26Å; L227-M239 WeakPolarHBondContact O-CA 3.2Å; L227-M239 WeakPolarHBondContact O-CG 3.29Å; L227-I240 PolarHBondContact N-O 3.01Å; L227-I240 PolarHBondContact O-N 3.26Å; L227-W242 HydrophobicContact CB-CZ3 4.47Å; L227-W242 HydrophobicContact CD1-CH2 3.91Å; L227-W242 HydrophobicContact CD1-CZ3 3.87Å; L227-W242 HydrophobicContact CG-CH2 4.41Å; L227-W242 HydrophobicContact CG-CZ3 3.87Å; L227-V362 HydrophobicContact CD2-CG2 4.22Å; L227-V475 HydrophobicContact CD1-CG1 4.18Å; L227-V475 HydrophobicContact CD2-CG1 4.33Å; L227-V475 HydrophobicContact CD2-CG2 3.98Å
228K98.3Very high93.2Very high35 Ų3533.5 Ų33.515%0.15219%0.194CC..EExtended strand (participates in β ladder)trans-92.4128.1172.5162.2171-179.1-171.20109I186 Y187 T230 Y355 A358I186-K228 CarbonylContact C-O 3.57Å; I186-K228 VanDerWaalsContact CA-O 3.31Å; I186-K228 WeakPolarHBondContact CA-O 3.24Å; Y187-K228 HydrophobicContact CD2-CG 4.45Å; Y187-K228 PolarHBondContact N-O 3.33Å; Y187-K228 PolarHBondContact O-N 2.97Å; K228-T230 HydrophobicContact CD-CG2 4.25Å; K228-T230 HydrophobicContact CG-CG2 3.97Å; K228-Y355 HydrophobicContact CB-CD2 3.72Å; K228-Y355 HydrophobicContact CB-CE2 3.61Å; K228-Y355 HydrophobicContact CD-CD1 4.37Å; K228-Y355 HydrophobicContact CD-CD2 4.13Å; K228-Y355 HydrophobicContact CD-CE1 4.01Å; K228-Y355 HydrophobicContact CD-CE2 3.8Å; K228-Y355 HydrophobicContact CD-CG 4.39Å; K228-Y355 WeakPolarHBondContact CD-O 3.48Å; K228-Y355 HydrophobicContact CG-CD2 3.96Å; K228-Y355 HydrophobicContact CG-CE1 4.48Å; K228-Y355 HydrophobicContact CG-CE2 3.41Å; K228-Y355 VanDerWaalsContact CG-CE2 3.41Å; K228-A358 HydrophobicContact CB-CB 4.2Å; K228-A358 HydrophobicContact CD-CB 4.24Å
229F98.3Very high93.2Very high1 Ų131.8 Ų31.80%0.00418%0.183CC..EExtended strand (participates in β ladder)trans-106.2131.8174.2-57.9-92.3000108.9I49 F87 I89 I186 L227 I237 G238 I240I49-F229 HydrophobicContact CD1-CD1 4.26Å; I49-F229 HydrophobicContact CG2-CB 4.18Å; I49-F229 HydrophobicContact CG2-CD1 3.63Å; I49-F229 HydrophobicContact CG2-CE1 4.47Å; I49-F229 HydrophobicContact CG2-CG 4.24Å; F87-F229 HydrophobicContact CD1-CD2 4.11Å; F87-F229 AromaticContact CD1-CE2 3.87Å; F87-F229 HydrophobicContact CD1-CE2 3.87Å; F87-F229 HydrophobicContact CD1-CZ 4.27Å; F87-F229 HydrophobicContact CE1-CD2 4.33Å; F87-F229 HydrophobicContact CE1-CE2 4.26Å; I89-F229 HydrophobicContact CD1-CE1 4.06Å; I89-F229 HydrophobicContact CG1-CE1 3.93Å; I186-F229 HydrophobicContact CD1-CD1 4.03Å; I186-F229 HydrophobicContact CD1-CE1 3.77Å; I186-F229 HydrophobicContact CG1-CD1 3.78Å; I186-F229 HydrophobicContact CG1-CE1 3.97Å; I186-F229 HydrophobicContact CG2-CD1 4.45Å; I186-F229 HydrophobicContact CG2-CE1 4.24Å; L227-F229 HydrophobicContact CB-CE2 3.87Å; L227-F229 HydrophobicContact CB-CZ 4.01Å; L227-F229 HydrophobicContact CD1-CZ 4.4Å; L227-F229 WeakPolarHBondContact O-CE2 3.28Å; F229-I237 HydrophobicContact CB-CD1 4.4Å; F229-I237 HydrophobicContact CB-CG1 3.82Å; F229-I237 PolarHBondContact O-N 2.78Å; F229-G238 PolarHBondContact N-O 3.49Å; F229-G238 PolarHBondContact O-N 2.98Å; F229-I240 HydrophobicContact CE2-CB 4.29Å; F229-I240 HydrophobicContact CE2-CD1 3.8Å; F229-I240 HydrophobicContact CE2-CG1 3.73Å; F229-I240 HydrophobicContact CZ-CD1 3.69Å; F229-I240 HydrophobicContact CZ-CG1 4.17Å
230T96.4Very high93.3Very high4 Ų429.6 Ų29.63%0.02517%0.171CC..EExtended strand (participates in β ladder)trans-129.9149.1179.852.60000109.3G184 R185 Y187 K228G184-T230 CarbonylContact C-O 3.5Å; G184-T230 WeakPolarHBondContact CA-O 3.47Å; R185-T230 PolarHBondContact N-O 2.92Å; R185-T230 PolarHBondContact O-N 2.69Å; R185-T230 PolarHBondContact O-OG1 3.28Å; Y187-T230 HydrophobicContact CD2-CG2 4.31Å; Y187-T230 HydrophobicContact CE2-CG2 4.23Å; Y187-T230 WeakPolarHBondContact CE2-OG1 3.5Å; K228-T230 HydrophobicContact CD-CG2 4.25Å; K228-T230 HydrophobicContact CG-CG2 3.97Å
231D90.5Very high93.3Very high22 Ų2229.5 Ų29.512%0.11817%0.17CC..EExtended strand (participates in β ladder)trans-79.9-175.9158.855.833000110.6K182 D233 G234 D235 I237K182-D231 HydrophobicContact CD-CB 3.88Å; K182-D231 HydrophobicContact CG-CB 4.45Å; K182-D231 IonicContact NZ-OD2 2.92Å; K182-D231 PolarHBondContact NZ-OD2 2.84Å; D231-D233 PolarHBondContact O-N 2.88Å; D231-D233 PolarHBondContact OD1-N 3.45Å; D231-G234 PolarHBondContact O-N 3.35Å; D231-G234 PolarHBondContact OD1-N 3.42Å; D231-D235 PolarHBondContact N-O 3.14Å; D231-I237 HydrophobicContact CB-CG2 4.03Å
232L88.3Confident93.3Very high100 Ų10029.2 Ų29.252%0.52417%0.168SC..THydrogen-bonded Turntrans-70.4-18.3-178-64.1-177.6000113.6P46 P183 G234P46-L232 HydrophobicContact CB-CD2 4Å; P46-L232 HydrophobicContact CG-CD2 4.34Å; P183-L232 HydrophobicContact CB-CD1 3.79Å; P183-L232 HydrophobicContact CB-CD2 4.48Å; P183-L232 HydrophobicContact CB-CG 4Å; L232-G234 PolarHBondContact O-N 2.91Å
233D79.6Confident93.3Very high148 Ų14828 Ų2879%0.79116%0.163SC*.THydrogen-bonded Turntrans-81.2-10178.7-60.8-41000111.5D231 D235D231-D233 PolarHBondContact O-N 2.88Å; D231-D233 PolarHBondContact OD1-N 3.45Å; D233-D235 VanDerWaalsContact C-N 3.31Å
234G71.4Confident93.4Very high42 Ų4225.5 Ų25.543%0.43315%0.15SC..  trans88.9-5.8174.300000114D231 L232 G236D231-G234 PolarHBondContact O-N 3.35Å; D231-G234 PolarHBondContact OD1-N 3.42Å; L232-G234 PolarHBondContact O-N 2.91Å; G234-G236 PolarHBondContact O-N 2.83Å
235D70.3Confident93.4Very high124 Ų12425.5 Ų25.566%0.66315%0.15SC*.  trans-72.7127.9171.9-78-26.2000109.1D231 D233 I237D231-D235 PolarHBondContact N-O 3.14Å; D233-D235 VanDerWaalsContact C-N 3.31Å; D235-I237 PolarHBondContact O-N 2.87Å
236G87.1Confident93.4Very high26 Ų2625.2 Ų25.227%0.26815%0.149SC..EExtended strand (participates in β ladder)trans-57.7130.1179.900000112.9G234 F284 Y355G234-G236 PolarHBondContact O-N 2.83Å; G236-F284 WeakPolarHBondContact O-CD2 3.32Å; G236-Y355 WeakPolarHBondContact CA-OH 3.47Å
237I96.4Very high93.4Very high11 Ų1125.2 Ų25.26%0.05615%0.149CC..EExtended strand (participates in β ladder)trans-103.4-24.5175.366.4170.4000112I49 V51 F229 D231 D235 F284 V285I49-I237 HydrophobicContact CB-CD1 4.06Å; I49-I237 HydrophobicContact CG2-CD1 3.77Å; V51-I237 HydrophobicContact CG1-CD1 4.47Å; V51-I237 HydrophobicContact CG1-CG1 4.44Å; V51-I237 HydrophobicContact CG2-CB 4.5Å; V51-I237 WeakPolarHBondContact CG2-O 3.31Å; F229-I237 HydrophobicContact CB-CD1 4.4Å; F229-I237 HydrophobicContact CB-CG1 3.82Å; F229-I237 PolarHBondContact O-N 2.78Å; D231-I237 HydrophobicContact CB-CG2 4.03Å; D235-I237 PolarHBondContact O-N 2.87Å; I237-F284 WeakPolarHBondContact O-CA 3.47Å; I237-V285 PolarHBondContact O-N 2.74Å
238G98.1Very high93.4Very high0 Ų025 Ų250%015%0.147CC..EExtended strand (participates in β ladder)trans-174.9-180174.800000113.5F229 F284 V285F229-G238 PolarHBondContact N-O 3.49Å; F229-G238 PolarHBondContact O-N 2.98Å; G238-F284 VanDerWaalsContact CA-CE2 3.49Å; G238-V285 CarbonylContact C-O 3.57Å; G238-V285 WeakPolarHBondContact CA-O 3.48Å
239M98.4Very high93.4Very high0 Ų023.5 Ų23.50%014%0.141CC..EExtended strand (participates in β ladder)trans-147.8142.8179-172.3-16974.900111F87 V226 L227 L269 F284 V285 G287 F288 A351 Y355F87-M239 WeakPolarHBondContact CE1-O 3.49Å; F87-M239 WeakPolarHBondContact CZ-O 3.46Å; V226-M239 HydrophobicContact CG1-CG 3.59Å; V226-M239 HydrophobicContact CG1-SD 3.67Å; V226-M239 HydrophobicContact CG2-SD 4.02Å; L227-M239 CarbonylContact O-C 3.6Å; L227-M239 VanDerWaalsContact O-CA 3.26Å; L227-M239 WeakPolarHBondContact O-CA 3.2Å; L227-M239 WeakPolarHBondContact O-CG 3.29Å; M239-L269 HydrophobicContact CB-CD2 4.28Å; M239-L269 HydrophobicContact CE-CD2 3.14Å; M239-L269 HydrophobicContact SD-CD2 3.47Å; M239-L269 WeakPolarHBondContact SD-CD2 3.47Å; M239-F284 HydrophobicContact CB-CZ 4.11Å; M239-V285 PolarHBondContact N-O 3.22Å; M239-G287 PolarHBondContact O-N 2.87Å; M239-F288 HydrophobicContact CE-CD2 4.34Å; M239-F288 HydrophobicContact CE-CE1 4.19Å; M239-F288 HydrophobicContact CE-CE2 3.64Å; M239-F288 HydrophobicContact CE-CZ 3.56Å; M239-A351 HydrophobicContact CE-CB 3.91Å; M239-A351 HydrophobicContact SD-CB 4.22Å; M239-Y355 HydrophobicContact CB-CD2 3.87Å; M239-Y355 HydrophobicContact CB-CE2 3.98Å; M239-Y355 HydrophobicContact CG-CD2 3.71Å; M239-Y355 HydrophobicContact CG-CE2 4.29Å; M239-Y355 HydrophobicContact SD-CD2 3.78Å; M239-Y355 HydrophobicContact SD-CG 4.26Å
240I98.8Very high93.4Very high3 Ų323.4 Ų23.42%0.01514%0.141CC..EExtended strand (participates in β ladder)trans-114.2135.5158.4-53.8161000109.1F87 F98 V226 L227 F229 W242 G287F87-I240 HydrophobicContact CB-CD1 3.88Å; F87-I240 HydrophobicContact CB-CG1 4.49Å; F87-I240 HydrophobicContact CD1-CD1 3.95Å; F87-I240 HydrophobicContact CD1-CG1 3.68Å; F87-I240 HydrophobicContact CD2-CD1 3.67Å; F87-I240 HydrophobicContact CD2-CG1 3.53Å; F87-I240 HydrophobicContact CE1-CD1 4.44Å; F87-I240 HydrophobicContact CE1-CG1 3.66Å; F87-I240 HydrophobicContact CE2-CD1 4.2Å; F87-I240 HydrophobicContact CE2-CG1 3.53Å; F87-I240 HydrophobicContact CG-CD1 3.55Å; F87-I240 HydrophobicContact CG-CG1 3.63Å; F87-I240 HydrophobicContact CZ-CG1 3.6Å; F98-I240 HydrophobicContact CD1-CD1 3.72Å; F98-I240 HydrophobicContact CD1-CG1 4.44Å; F98-I240 HydrophobicContact CD1-CG2 4.43Å; F98-I240 HydrophobicContact CE1-CD1 4.33Å; F98-I240 HydrophobicContact CE1-CG2 3.97Å; F98-I240 HydrophobicContact CG-CD1 4.49Å; V226-I240 CarbonylContact C-O 3.44Å; V226-I240 WeakPolarHBondContact CA-O 3.13Å; L227-I240 PolarHBondContact N-O 3.01Å; L227-I240 PolarHBondContact O-N 3.26Å; F229-I240 HydrophobicContact CE2-CB 4.29Å; F229-I240 HydrophobicContact CE2-CD1 3.8Å; F229-I240 HydrophobicContact CE2-CG1 3.73Å; F229-I240 HydrophobicContact CZ-CD1 3.69Å; F229-I240 HydrophobicContact CZ-CG1 4.17Å; I240-W242 HydrophobicContact CB-CE3 4.48Å; I240-W242 HydrophobicContact CB-CH2 3.71Å; I240-W242 HydrophobicContact CB-CZ2 4.41Å; I240-W242 HydrophobicContact CB-CZ3 3.73Å; I240-W242 HydrophobicContact CD1-CH2 3.97Å; I240-W242 HydrophobicContact CG1-CH2 4.47Å; I240-W242 HydrophobicContact CG2-CD2 4.07Å; I240-W242 HydrophobicContact CG2-CE3 3.83Å; I240-W242 HydrophobicContact CG2-CH2 3.25Å; I240-W242 HydrophobicContact CG2-CZ2 3.49Å; I240-W242 VanDerWaalsContact CG2-CZ2 3.49Å; I240-W242 HydrophobicContact CG2-CZ3 3.41Å; I240-W242 VanDerWaalsContact CG2-CZ3 3.41Å; I240-G287 CarbonylContact C-O 3.56Å; I240-G287 VanDerWaalsContact CA-O 3.26Å; I240-G287 WeakPolarHBondContact CA-O 3.1Å
241S98.8Very high93.4Very high0 Ų024.8 Ų24.80%015%0.148CC..EExtended strand (participates in β ladder)trans-122.9139.8172.3-179.90000110.8V224 L225 G287 S289V224-S241 WeakPolarHBondContact CG1-OG 3.42Å; L225-S241 CarbonylContact O-C 3.53Å; L225-S241 VanDerWaalsContact O-CA 3.24Å; L225-S241 WeakPolarHBondContact O-CA 3.48Å; S241-G287 PolarHBondContact N-O 2.91Å; S241-S289 PolarHBondContact O-N 3.43Å
242W98.9Very high93.6Very high5 Ų526 Ų262%0.01915%0.151CC..EExtended strand (participates in β ladder)trans-117.2128.4171.5-70.5-95.1000110.2F98 V224 L225 L227 I240 S289 V477 V512 I513F98-W242 HydrophobicContact CD1-CZ2 4.42Å; F98-W242 AromaticContact CE1-CZ2 3.93Å; F98-W242 HydrophobicContact CE1-CZ2 3.93Å; F98-W242 HydrophobicContact CE2-CZ2 4.32Å; F98-W242 AromaticContact CZ-CZ2 3.89Å; F98-W242 HydrophobicContact CZ-CZ2 3.89Å; F98-W242 AromaticContact CZ-NE1 3.91Å; V224-W242 WeakPolarHBondContact CA-O 3.22Å; L225-W242 HydrophobicContact CD2-CE3 4.08Å; L225-W242 HydrophobicContact CD2-CZ3 4.28Å; L225-W242 PolarHBondContact N-O 3.02Å; L225-W242 VanDerWaalsContact N-O 3.15Å; L225-W242 PolarHBondContact O-N 3.32Å; L227-W242 HydrophobicContact CB-CZ3 4.47Å; L227-W242 HydrophobicContact CD1-CH2 3.91Å; L227-W242 HydrophobicContact CD1-CZ3 3.87Å; L227-W242 HydrophobicContact CG-CH2 4.41Å; L227-W242 HydrophobicContact CG-CZ3 3.87Å; I240-W242 HydrophobicContact CB-CE3 4.48Å; I240-W242 HydrophobicContact CB-CH2 3.71Å; I240-W242 HydrophobicContact CB-CZ2 4.41Å; I240-W242 HydrophobicContact CB-CZ3 3.73Å; I240-W242 HydrophobicContact CD1-CH2 3.97Å; I240-W242 HydrophobicContact CG1-CH2 4.47Å; I240-W242 HydrophobicContact CG2-CD2 4.07Å; I240-W242 HydrophobicContact CG2-CE3 3.83Å; I240-W242 HydrophobicContact CG2-CH2 3.25Å; I240-W242 HydrophobicContact CG2-CZ2 3.49Å; I240-W242 VanDerWaalsContact CG2-CZ2 3.49Å; I240-W242 HydrophobicContact CG2-CZ3 3.41Å; I240-W242 VanDerWaalsContact CG2-CZ3 3.41Å; W242-S289 PolarHBondContact NE1-OG 3.48Å; W242-V477 HydrophobicContact CH2-CG2 4.18Å; W242-V477 HydrophobicContact CZ2-CG1 4.12Å; W242-V477 HydrophobicContact CZ2-CG2 3.95Å; W242-V512 HydrophobicContact CD2-CB 4.27Å; W242-V512 HydrophobicContact CD2-CG1 4.48Å; W242-V512 HydrophobicContact CD2-CG2 4.02Å; W242-V512 HydrophobicContact CE3-CG1 4.47Å; W242-V512 HydrophobicContact CE3-CG2 4.35Å; W242-V512 HydrophobicContact CG-CB 4.27Å; W242-V512 HydrophobicContact CG-CG2 4.46Å; W242-V512 HydrophobicContact CH2-CG2 4.45Å; W242-V512 HydrophobicContact CZ2-CG2 4.15Å; W242-I513 VanDerWaalsContact CD1-O 3.28Å
243F98.8Very high93.9Very high1 Ų125.3 Ų25.30%0.00415%0.151CC..EExtended strand (participates in β ladder)trans-144143.6173.7-177.7-124.3000110.2L193 V224 V245 I347L193-F243 HydrophobicContact CB-CE2 4.11Å; L193-F243 HydrophobicContact CB-CZ 4.27Å; L193-F243 HydrophobicContact CD2-CD1 4.33Å; L193-F243 HydrophobicContact CD2-CE1 3.9Å; L193-F243 HydrophobicContact CD2-CE2 4.29Å; L193-F243 HydrophobicContact CD2-CZ 3.88Å; L193-F243 HydrophobicContact CG-CZ 4.18Å; V224-F243 HydrophobicContact CG2-CB 4.23Å; V224-F243 HydrophobicContact CG2-CD2 3.55Å; V224-F243 HydrophobicContact CG2-CE2 4.11Å; V224-F243 HydrophobicContact CG2-CG 4.01Å; F243-V245 HydrophobicContact CD1-CB 4.04Å; F243-V245 HydrophobicContact CD1-CG1 3.53Å; F243-V245 HydrophobicContact CE1-CB 3.82Å; F243-V245 HydrophobicContact CE1-CG1 3.69Å; F243-V245 PolarHBondContact O-N 3.42Å; F243-I347 HydrophobicContact CD1-CD1 3.98Å; F243-I347 HydrophobicContact CD1-CG1 3.89Å; F243-I347 HydrophobicContact CE1-CD1 4.23Å; F243-I347 HydrophobicContact CE1-CG1 4.06Å
244A98.6Very high94.8Very high2 Ų218.6 Ų18.62%0.01712%0.115CC..  trans-92.992.8-177.700000110.3D221 V296D221-A244 HydrophobicContact CB-CB 4.19Å; A244-V296 WeakPolarHBondContact O-CG1 3.41Å
245V98.8Very high96Very high0 Ų022 Ų220%012%0.115CC..  trans-155.3141.3170.368.50000109.9F243 M262 L293 P298 I347F243-V245 HydrophobicContact CD1-CB 4.04Å; F243-V245 HydrophobicContact CD1-CG1 3.53Å; F243-V245 HydrophobicContact CE1-CB 3.82Å; F243-V245 HydrophobicContact CE1-CG1 3.69Å; F243-V245 PolarHBondContact O-N 3.42Å; V245-M262 HydrophobicContact CG1-SD 4.06Å; V245-L293 WeakPolarHBondContact O-CD2 3.37Å; V245-P298 HydrophobicContact CG2-CB 3.72Å; V245-P298 HydrophobicContact CG2-CG 4.41Å; V245-I347 HydrophobicContact CG1-CD1 3.97Å
246H98.6Very high97.4Very high0 Ų016.4 Ų16.40%09%0.085CC..  trans-63.5141.8170.5-85.778.1000111.6H137 R200 V248 N261 L293 V296 P298 E483H137-H246 AromaticContact CD2-CD2 3.2Å; H137-H246 PolarHBondContact CD2-CD2 3.28Å; H137-H246 AromaticContact CD2-NE2 3.52Å; H137-H246 AromaticContact NE2-CD2 3.21Å; H137-H246 PolarHBondContact NE2-CD2 2.99Å; H137-H246 AromaticContact NE2-NE2 3.25Å; H137-H246 PolarHBondContact NE2-NE2 3.11Å; R200-H246 VanDerWaalsContact CZ-CE1 3.46Å; R200-H246 PolarHBondContact NH1-CE1 3.42Å; R200-H246 PolarHBondContact NH2-CE1 2.81Å; R200-H246 PolarHBondContact NH2-NE2 2.97Å; H246-V248 VanDerWaalsContact C-N 3.28Å; H246-V248 HydrophobicContact CB-CB 4.25Å; H246-V248 HydrophobicContact CB-CG1 4.01Å; H246-V248 HydrophobicContact CB-CG2 3.43Å; H246-V248 VanDerWaalsContact CB-CG2 3.43Å; H246-V248 PolarHBondContact O-N 2.9Å; H246-N261 PolarHBondContact O-ND2 2.84Å; H246-L293 WeakPolarHBondContact CE1-CD1 3.21Å; H246-L293 PolarHBondContact CE1-O 2.92Å; H246-L293 PolarHBondContact ND1-O 2.92Å; H246-V296 WeakPolarHBondContact CB-O 3.17Å; H246-V296 PolarHBondContact N-O 3.34Å; H246-V296 PolarHBondContact ND1-O 2.79Å; H246-P298 VanDerWaalsContact O-CD 3.31Å; H246-P298 WeakPolarHBondContact O-CD 3.26Å; H246-P298 VanDerWaalsContact O-CG 3.3Å; H246-P298 WeakPolarHBondContact O-CG 3.5Å; H246-E483 IonicContact CD2-OE2 3.93Å; H246-E483 IonicContact CE1-OE2 3.26Å; H246-E483 PolarHBondContact CE1-OE2 3.15Å; H246-E483 IonicContact NE2-OE2 3.84Å; H246-E483 PolarHBondContact NE2-OE2 2.82Å
247A98.5Very high97.9Very high0 Ų015.2 Ų15.20%07%0.073CC..BIsolated β-bridgetrans-89.767.3168.800000110.4H137 H139 D260 N261 M262H137-A247 VanDerWaalsContact O-CB 3.31Å; H137-A247 WeakPolarHBondContact O-CB 3.49Å; H139-A247 PolarHBondContact N-O 2.72Å; A247-D260 WeakPolarHBondContact CA-OD1 3.27Å; A247-D260 HydrophobicContact CB-CB 3.93Å; A247-N261 WeakPolarHBondContact CA-OD1 3.45Å; A247-N261 WeakPolarHBondContact CB-OD1 3.24Å; A247-M262 HydrophobicContact CB-CG 4.25Å
248V98.5Very high98Very high1 Ų114.7 Ų14.71%0.0067%0.07CC..  trans-130.926.5-175.7-64.10000112.2Y68 H139 H246 M250 D260 P298 D405Y68-V248 HydrophobicContact CE1-CG1 4.48Å; Y68-V248 VanDerWaalsContact OH-CB 3.28Å; Y68-V248 WeakPolarHBondContact OH-CB 3.35Å; Y68-V248 PolarHBondContact OH-O 3.1Å; H139-V248 HydrophobicContact CB-CG1 4.19Å; H139-V248 VanDerWaalsContact CD2-CG1 3.43Å; H139-V248 WeakPolarHBondContact CD2-CG1 3.08Å; H246-V248 VanDerWaalsContact C-N 3.28Å; H246-V248 HydrophobicContact CB-CB 4.25Å; H246-V248 HydrophobicContact CB-CG1 4.01Å; H246-V248 HydrophobicContact CB-CG2 3.43Å; H246-V248 VanDerWaalsContact CB-CG2 3.43Å; H246-V248 PolarHBondContact O-N 2.9Å; V248-M250 VanDerWaalsContact C-N 3.26Å; V248-D260 PolarHBondContact N-OD1 2.97Å; V248-P298 VanDerWaalsContact CG2-CD 3.4Å; V248-P298 HydrophobicContact CG2-CG 3.7Å; V248-D405 HydrophobicContact CG2-CB 4.01Å
249S98.6Very high98.1Very high3 Ų315 Ų152%0.0217%0.072CC..SBendtrans-68.1-32.8173.4-68.90000111N251 D260 N261 P298 T340S249-N251 PolarHBondContact O-N 2.84Å; S249-D260 WeakPolarHBondContact CB-OD1 3.5Å; S249-D260 PolarHBondContact N-OD1 2.92Å; S249-D260 PolarHBondContact N-OD2 3.31Å; S249-N261 PolarHBondContact OG-ND2 2.88Å; S249-P298 WeakPolarHBondContact OG-CB 3.44Å; S249-P298 WeakPolarHBondContact OG-CG 3.28Å; S249-T340 VanDerWaalsContact CB-CA 3.49Å; S249-T340 WeakPolarHBondContact CB-OG1 3.35Å
250M98.3Very high98.1Very high0 Ų015 Ų150%07%0.072CC..SBendtrans-81.9100.6166.9-61.7-65.9-76.300109.8Y68 C140 V248 N254 D260 M336 F337 T340Y68-M250 WeakPolarHBondContact CE2-O 3.34Å; Y68-M250 PolarHBondContact OH-O 3.06Å; C140-M250 WeakPolarHBondContact SG-CB 3.4Å; V248-M250 VanDerWaalsContact C-N 3.26Å; M250-N254 HydrophobicContact CB-CB 4.36Å; M250-N254 HydrophobicContact CE-CB 4.18Å; M250-D260 WeakPolarHBondContact CB-OD2 3.24Å; M250-D260 VanDerWaalsContact CG-OD2 3.3Å; M250-D260 WeakPolarHBondContact CG-OD2 3.42Å; M250-D260 PolarHBondContact N-OD2 3.03Å; M250-M336 HydrophobicContact CE-CG 4.31Å; M250-M336 HydrophobicContact CE-SD 3.74Å; M250-M336 HydrophobicContact SD-CB 4.11Å; M250-M336 HydrophobicContact SD-CG 3.89Å; M250-M336 HydrophobicContact SD-SD 3.94Å; M250-F337 HydrophobicContact CE-CD1 3.67Å; M250-F337 HydrophobicContact CE-CE1 3.24Å; M250-F337 HydrophobicContact CE-CG 4.46Å; M250-F337 HydrophobicContact CE-CZ 3.72Å; M250-F337 HydrophobicContact SD-CD1 3.93Å; M250-F337 HydrophobicContact SD-CE1 4.13Å; M250-F337 HydrophobicContact SD-CG 4.38Å; M250-T340 HydrophobicContact CG-CG2 4.26Å; M250-T340 WeakPolarHBondContact CG-OG1 3.36Å; M250-T340 PolarHBondContact N-OG1 3.42Å; M250-T340 PolarHBondContact SD-OG1 2.85Å; M250-T340 VanDerWaalsContact SD-OG1 3.4Å
251N96.4Very high98.1Very high33 Ų3314.8 Ų14.818%0.1767%0.071CC..  trans-68.5173.5-174.98033.7000114.1Y68 S249 T253 N254 M336Y68-N251 WeakPolarHBondContact OH-CA 3.41Å; S249-N251 PolarHBondContact O-N 2.84Å; N251-T253 PolarHBondContact O-N 2.82Å; N251-T253 WeakPolarHBondContact OD1-CB 3.44Å; N251-T253 PolarHBondContact OD1-N 3.34Å; N251-T253 PolarHBondContact OD1-OG1 2.91Å; N251-N254 VanDerWaalsContact O-CB 3.24Å; N251-N254 WeakPolarHBondContact O-CB 3.39Å; N251-N254 PolarHBondContact O-N 2.93Å; N251-M336 HydrophobicContact CB-CE 4.04Å; N251-M336 WeakPolarHBondContact ND2-CE 3.32Å; N251-M336 WeakPolarHBondContact OD1-CE 3.46Å
252Y93.8Very high98.1Very high47 Ų4714.9 Ų14.918%0.1847%0.071CC..THydrogen-bonded Turntrans-60.1-10.8-176.668.7-96.4000116.2Y68 N70 Q73 Q328Y68-Y252 VanDerWaalsContact CG-CB 3.5Å; N70-Y252 WeakPolarHBondContact ND2-CD2 3.35Å; Q73-Y252 WeakPolarHBondContact CG-O 3.43Å; Y252-Q328 PolarHBondContact OH-NE2 3.39Å
253T95.6Very high98Very high85 Ų8514.7 Ų14.752%0.5217%0.071SC..THydrogen-bonded Turntrans-82.4-15.5173.768.90000112.7N251 M336N251-T253 PolarHBondContact O-N 2.82Å; N251-T253 WeakPolarHBondContact OD1-CB 3.44Å; N251-T253 PolarHBondContact OD1-N 3.34Å; N251-T253 PolarHBondContact OD1-OG1 2.91Å; T253-M336 WeakPolarHBondContact OG1-CE 3.45Å
254N97.7Very high98Very high7 Ų715.3 Ų15.34%0.0377%0.074CC..  trans-62.1137.1174.5173.448.7000111.1Q73 C140 M250 N251 M256 M336Q73-N254 WeakPolarHBondContact CG-O 3.26Å; Q73-N254 PolarHBondContact NE2-O 3.36Å; C140-N254 PolarHBondContact SG-ND2 3.18Å; M250-N254 HydrophobicContact CB-CB 4.36Å; M250-N254 HydrophobicContact CE-CB 4.18Å; N251-N254 VanDerWaalsContact O-CB 3.24Å; N251-N254 WeakPolarHBondContact O-CB 3.39Å; N251-N254 PolarHBondContact O-N 2.93Å; N254-M256 PolarHBondContact ND2-O 3.43Å; N254-M256 PolarHBondContact OD1-N 2.81Å; N254-M336 HydrophobicContact CB-CE 4.18Å; N254-M336 HydrophobicContact CB-SD 3.83Å
255R97.9Very high98Very high114 Ų11415.2 Ų15.243%0.437%0.073SC..  trans-121.26.2174.7-63.4-172.267-166.11.8113.3T74 A75 A76T74-R255 WeakPolarHBondContact O-CB 3.23Å; T74-R255 PolarHBondContact O-NE 3Å; T74-R255 PolarHBondContact O-NH2 3.47Å; T74-R255 PolarHBondContact OG1-NH2 3.17Å; A75-R255 CarbonylContact C-O 3.55Å; A75-R255 VanDerWaalsContact CA-O 3.29Å; A75-R255 WeakPolarHBondContact CA-O 3.29Å; A76-R255 HydrophobicContact CB-CB 3.96Å; A76-R255 PolarHBondContact N-O 3.38Å
256M98Very high98.1Very high7 Ų715.2 Ų15.23%0.0347%0.073CC..SBendtrans-97.2143.6177.1-63.9-166.1-74.100111.3G77 H79 N254 S258 F337 R662 H664G77-M256 WeakPolarHBondContact O-CA 3.4Å; H79-M256 HydrophobicContact CB-CB 4.01Å; H79-M256 HydrophobicContact CB-CE 3.94Å; H79-M256 HydrophobicContact CB-SD 4.18Å; N254-M256 PolarHBondContact ND2-O 3.43Å; N254-M256 PolarHBondContact OD1-N 2.81Å; M256-S258 PolarHBondContact O-N 2.88Å; M256-F337 HydrophobicContact CE-CE1 3.23Å; M256-F337 HydrophobicContact CE-CE2 4.42Å; M256-F337 HydrophobicContact CE-CZ 3.17Å; M256-R662 HydrophobicContact CE-CB 4.47Å; M256-R662 HydrophobicContact CE-CG 4.24Å; M256-R662 HydrophobicContact SD-CB 4.12Å; M256-R662 HydrophobicContact SD-CG 4.48Å; M256-H664 VanDerWaalsContact SD-CE1 3.57Å
257V98.7Very high98.1Very high0 Ų016.4 Ų16.40%08%0.077CC..BIsolated β-bridgetrans-63.2129.5168177.30000109.1T57 P60 L65 A75 G77 I78 H79 T80 L82 C140 P142T57-V257 HydrophobicContact CG2-CG1 4.05Å; P60-V257 HydrophobicContact CB-CG2 3.94Å; L65-V257 HydrophobicContact CD2-CG2 4.45Å; A75-V257 HydrophobicContact CB-CG2 4.36Å; G77-V257 PolarHBondContact O-N 2.98Å; I78-V257 HydrophobicContact CG1-CB 4.36Å; H79-V257 PolarHBondContact N-O 2.83Å; T80-V257 PolarHBondContact N-O 3.5Å; L82-V257 HydrophobicContact CD1-CG1 3.73Å; L82-V257 HydrophobicContact CD2-CG1 3.97Å; L82-V257 HydrophobicContact CG-CG1 3.68Å; C140-V257 VanDerWaalsContact O-CA 3.31Å; C140-V257 WeakPolarHBondContact O-CA 3.49Å; P142-V257 HydrophobicContact CG-CG2 3.97Å
258S98.8Very high98.1Very high0 Ų017.5 Ų17.50%08%0.083CC..  trans-153.7147.4-178.5-177.50000111.3L82 T138 C140 M256 D260L82-S258 WeakPolarHBondContact CD2-O 3.42Å; T138-S258 PolarHBondContact OG1-O 3.15Å; C140-S258 VanDerWaalsContact CB-O 3.29Å; C140-S258 WeakPolarHBondContact CB-O 3.39Å; C140-S258 PolarHBondContact O-N 3.46Å; M256-S258 PolarHBondContact O-N 2.88Å; S258-D260 VanDerWaalsContact C-N 3.27Å; S258-D260 PolarHBondContact OG-N 3.18Å
259S98.6Very high98.1Very high6 Ų617.5 Ų17.54%0.0428%0.083CC..  trans-85.42173.660.10000113.3T80 G263T80-S259 PolarHBondContact OG1-N 2.92Å; T80-S259 PolarHBondContact OG1-OG 3.49Å; S259-G263 WeakPolarHBondContact O-CA 3.42Å; S259-G263 PolarHBondContact O-N 2.94Å; S259-G263 WeakPolarHBondContact OG-CA 3.33Å
260D98.8Very high98.1Very high0 Ų017.8 Ų17.80%08%0.084CC..Hα-helixtrans54.1-153.9177.8-155.1-84.8000112.9A247 V248 S249 M250 S258 G263 Y264A247-D260 WeakPolarHBondContact CA-OD1 3.27Å; A247-D260 HydrophobicContact CB-CB 3.93Å; V248-D260 PolarHBondContact N-OD1 2.97Å; S249-D260 WeakPolarHBondContact CB-OD1 3.5Å; S249-D260 PolarHBondContact N-OD1 2.92Å; S249-D260 PolarHBondContact N-OD2 3.31Å; M250-D260 WeakPolarHBondContact CB-OD2 3.24Å; M250-D260 VanDerWaalsContact CG-OD2 3.3Å; M250-D260 WeakPolarHBondContact CG-OD2 3.42Å; M250-D260 PolarHBondContact N-OD2 3.03Å; S258-D260 VanDerWaalsContact C-N 3.27Å; S258-D260 PolarHBondContact OG-N 3.18Å; D260-G263 PolarHBondContact O-N 3.45Å; D260-Y264 WeakPolarHBondContact O-CB 3.39Å; D260-Y264 PolarHBondContact O-N 2.98Å
261N98.8Very high98Very high0 Ų020.9 Ų20.90%010%0.099CC..Hα-helixtrans-68.9-40.4-169.456.429.1000113.3H246 A247 S249 Y264 A265 P298 T340 I343 G344H246-N261 PolarHBondContact O-ND2 2.84Å; A247-N261 WeakPolarHBondContact CA-OD1 3.45Å; A247-N261 WeakPolarHBondContact CB-OD1 3.24Å; S249-N261 PolarHBondContact OG-ND2 2.88Å; N261-Y264 PolarHBondContact O-N 2.66Å; N261-A265 PolarHBondContact O-N 3.24Å; N261-P298 WeakPolarHBondContact ND2-CB 3.42Å; N261-T340 HydrophobicContact CB-CG2 4.13Å; N261-T340 VanDerWaalsContact N-CG2 3.34Å; N261-I343 HydrophobicContact CB-CB 4.15Å; N261-I343 HydrophobicContact CB-CG2 3.86Å; N261-G344 WeakPolarHBondContact O-CA 3.16Å
262M98.4Very high98Very high1 Ų122.7 Ų22.71%0.00511%0.108CC..Hα-helixtrans-67.3-39175.8-64.3-60.9-85.400111.3V245 A247 A265 S266 F288 S289 I347V245-M262 HydrophobicContact CG1-SD 4.06Å; A247-M262 HydrophobicContact CB-CG 4.25Å; M262-A265 PolarHBondContact O-N 3.22Å; M262-S266 PolarHBondContact O-N 3.18Å; M262-S266 PolarHBondContact O-OG 3.3Å; M262-F288 HydrophobicContact CB-CB 4.4Å; M262-F288 HydrophobicContact CE-CB 3.94Å; M262-S289 WeakPolarHBondContact CE-O 3.35Å; M262-I347 HydrophobicContact SD-CD1 3.98Å
263G98.6Very high98.1Very high1 Ų124.9 Ų24.91%0.0112%0.119CC..Hα-helixtrans-68.2-39.3173.900000112.9S259 D260 A265 S266 Y267S259-G263 WeakPolarHBondContact O-CA 3.42Å; S259-G263 PolarHBondContact O-N 2.94Å; S259-G263 WeakPolarHBondContact OG-CA 3.33Å; D260-G263 PolarHBondContact O-N 3.45Å; G263-A265 VanDerWaalsContact C-N 3.33Å; G263-A265 PolarHBondContact O-N 3.49Å; G263-S266 WeakPolarHBondContact O-CB 3.14Å; G263-S266 PolarHBondContact O-N 3.26Å; G263-S266 VanDerWaalsContact O-N 3.16Å; G263-Y267 WeakPolarHBondContact O-CB 3.48Å; G263-Y267 PolarHBondContact O-N 3.06Å
264Y98.8Very high98.2Very high15 Ų1521.4 Ų21.46%0.05910%0.097CC..Hα-helixtrans-64.7-37174.3-173-117.4000112.3D260 N261 S266 Y267 L268 R341 H345 W659D260-Y264 WeakPolarHBondContact O-CB 3.39Å; D260-Y264 PolarHBondContact O-N 2.98Å; N261-Y264 PolarHBondContact O-N 2.66Å; Y264-S266 VanDerWaalsContact C-N 3.31Å; Y264-S266 PolarHBondContact O-N 3.16Å; Y264-Y267 AromaticContact CD2-CD1 3.95Å; Y264-Y267 HydrophobicContact CD2-CD1 3.95Å; Y264-Y267 AromaticContact CE2-CD1 3.81Å; Y264-Y267 HydrophobicContact CE2-CD1 3.81Å; Y264-Y267 HydrophobicContact CE2-CE1 4.13Å; Y264-Y267 WeakPolarHBondContact O-CB 3.37Å; Y264-Y267 PolarHBondContact O-N 3.29Å; Y264-L268 HydrophobicContact CD1-CD1 4.06Å; Y264-L268 HydrophobicContact CD1-CG 4.47Å; Y264-L268 HydrophobicContact CE1-CD1 3.53Å; Y264-L268 HydrophobicContact CE1-CD2 4.5Å; Y264-L268 HydrophobicContact CE1-CG 4.05Å; Y264-L268 HydrophobicContact CE2-CD2 4.22Å; Y264-L268 HydrophobicContact CE2-CG 4.17Å; Y264-L268 WeakPolarHBondContact O-CG 3.36Å; Y264-L268 PolarHBondContact O-N 2.97Å; Y264-R341 HydrophobicContact CD1-CG 4.37Å; Y264-R341 WeakPolarHBondContact CD1-O 3.41Å; Y264-R341 HydrophobicContact CE1-CB 4.04Å; Y264-R341 HydrophobicContact CE1-CG 3.44Å; Y264-R341 VanDerWaalsContact CE1-CG 3.44Å; Y264-R341 VanDerWaalsContact CE1-O 3.3Å; Y264-R341 WeakPolarHBondContact CE1-O 3.4Å; Y264-R341 WeakPolarHBondContact OH-CG 3.5Å; Y264-H345 HydrophobicContact CE1-CB 4.3Å; Y264-W659 HydrophobicContact CD2-CB 4.4Å; Y264-W659 AromaticContact CD2-CD2 3.36Å; Y264-W659 HydrophobicContact CD2-CD2 3.36Å; Y264-W659 AromaticContact CD2-CE2 3.9Å; Y264-W659 AromaticContact CD2-CE3 3.17Å; Y264-W659 HydrophobicContact CD2-CE3 3.17Å; Y264-W659 AromaticContact CD2-CG 3.93Å; Y264-W659 HydrophobicContact CD2-CG 3.93Å; Y264-W659 HydrophobicContact CD2-CH2 4.03Å; Y264-W659 HydrophobicContact CD2-CZ2 4.22Å; Y264-W659 AromaticContact CD2-CZ3 3.53Å; Y264-W659 HydrophobicContact CD2-CZ3 3.53Å; Y264-W659 HydrophobicContact CE2-CB 3.91Å; Y264-W659 AromaticContact CE2-CD1 3.88Å; Y264-W659 AromaticContact CE2-CD2 3.33Å; Y264-W659 HydrophobicContact CE2-CD2 3.33Å; Y264-W659 AromaticContact CE2-CE2 3.75Å; Y264-W659 AromaticContact CE2-CE3 3.69Å; Y264-W659 HydrophobicContact CE2-CE3 3.69Å; Y264-W659 AromaticContact CE2-CG 3.43Å; Y264-W659 HydrophobicContact CE2-CG 3.43Å; Y264-W659 VanDerWaalsContact CE2-CG 3.43Å; Y264-W659 HydrophobicContact CE2-CZ2 4.41Å; Y264-W659 HydrophobicContact CE2-CZ3 4.34Å; Y264-W659 HydrophobicContact CG-CD2 4.3Å; Y264-W659 AromaticContact CG-CE3 3.96Å; Y264-W659 HydrophobicContact CG-CE3 3.96Å; Y264-W659 HydrophobicContact CG-CH2 4.05Å; Y264-W659 HydrophobicContact CG-CZ2 4.41Å; Y264-W659 AromaticContact CG-CZ3 3.83Å; Y264-W659 HydrophobicContact CG-CZ3 3.83Å
265A98.9Very high98.1Very high0 Ų026.3 Ų26.30%013%0.129CC..Hα-helixtrans-62.7-40172.100000112N261 M262 G263 L269 F288 G344 I347N261-A265 PolarHBondContact O-N 3.24Å; M262-A265 PolarHBondContact O-N 3.22Å; G263-A265 VanDerWaalsContact C-N 3.33Å; G263-A265 PolarHBondContact O-N 3.49Å; A265-L269 PolarHBondContact O-N 3.38Å; A265-F288 VanDerWaalsContact C-CE2 3.47Å; A265-F288 HydrophobicContact CB-CD1 3.82Å; A265-F288 HydrophobicContact CB-CD2 4.18Å; A265-F288 HydrophobicContact CB-CE1 3.76Å; A265-F288 HydrophobicContact CB-CE2 4.09Å; A265-F288 HydrophobicContact CB-CG 4.02Å; A265-F288 HydrophobicContact CB-CZ 3.87Å; A265-F288 VanDerWaalsContact O-CE2 3.31Å; A265-F288 WeakPolarHBondContact O-CE2 3.3Å; A265-G344 WeakPolarHBondContact CB-O 3.4Å; A265-I347 HydrophobicContact CB-CB 4.06Å; A265-I347 HydrophobicContact CB-CG2 3.8Å
266S98.9Very high97.9Very high0 Ų025.2 Ų25.20%015%0.153CC..Hα-helixtrans-63-48.7174.7-52.50000111.4M262 G263 Y264 L268 L269 E270 A286 F288M262-S266 PolarHBondContact O-N 3.18Å; M262-S266 PolarHBondContact O-OG 3.3Å; G263-S266 WeakPolarHBondContact O-CB 3.14Å; G263-S266 PolarHBondContact O-N 3.26Å; G263-S266 VanDerWaalsContact O-N 3.16Å; Y264-S266 VanDerWaalsContact C-N 3.31Å; Y264-S266 PolarHBondContact O-N 3.16Å; S266-L268 PolarHBondContact O-N 2.46Å; S266-L269 PolarHBondContact O-N 2.94Å; S266-E270 WeakPolarHBondContact O-CG 2.95Å; S266-E270 PolarHBondContact O-N 3.43Å; S266-A286 WeakPolarHBondContact CB-O 3.37Å; S266-A286 PolarHBondContact OG-O 2.98Å; S266-F288 VanDerWaalsContact OG-CD2 3.25Å; S266-F288 WeakPolarHBondContact OG-CD2 3.48Å
267Y98.7Very high97.8Very high24 Ų2429.1 Ų29.19%0.09417%0.171CC..Hα-helixtrans-51.5-54176170.5-92.8000111.5G263 Y264 L269 E270 E271 P279 W659 E660G263-Y267 WeakPolarHBondContact O-CB 3.48Å; G263-Y267 PolarHBondContact O-N 3.06Å; Y264-Y267 AromaticContact CD2-CD1 3.95Å; Y264-Y267 HydrophobicContact CD2-CD1 3.95Å; Y264-Y267 AromaticContact CE2-CD1 3.81Å; Y264-Y267 HydrophobicContact CE2-CD1 3.81Å; Y264-Y267 HydrophobicContact CE2-CE1 4.13Å; Y264-Y267 WeakPolarHBondContact O-CB 3.37Å; Y264-Y267 PolarHBondContact O-N 3.29Å; Y267-L269 VanDerWaalsContact C-N 3.33Å; Y267-L269 PolarHBondContact O-N 3.48Å; Y267-E270 PolarHBondContact O-N 2.78Å; Y267-E271 HydrophobicContact CD1-CG 4.33Å; Y267-E271 HydrophobicContact CD2-CG 4.39Å; Y267-E271 HydrophobicContact CE1-CG 4.06Å; Y267-E271 HydrophobicContact CE2-CG 4.16Å; Y267-E271 HydrophobicContact CG-CG 4.48Å; Y267-E271 WeakPolarHBondContact O-CB 3.25Å; Y267-E271 VanDerWaalsContact O-CG 3.32Å; Y267-E271 WeakPolarHBondContact O-CG 3.46Å; Y267-E271 PolarHBondContact O-N 2.85Å; Y267-P279 HydrophobicContact CD2-CB 4.16Å; Y267-P279 HydrophobicContact CD2-CG 4.47Å; Y267-P279 HydrophobicContact CE2-CB 3.61Å; Y267-P279 HydrophobicContact CE2-CG 3.52Å; Y267-W659 HydrophobicContact CE1-CB 3.94Å; Y267-W659 PolarHBondContact OH-N 3.43Å; Y267-E660 PolarHBondContact OH-OE2 3.34Å
268L98.7Very high97.8Very high24 Ų2430.7 Ų30.713%0.12618%0.18CC..Hα-helixtrans-62.2-38.6-177.9-72179000113Y264 S266 D272 H345 Y348Y264-L268 HydrophobicContact CD1-CD1 4.06Å; Y264-L268 HydrophobicContact CD1-CG 4.47Å; Y264-L268 HydrophobicContact CE1-CD1 3.53Å; Y264-L268 HydrophobicContact CE1-CD2 4.5Å; Y264-L268 HydrophobicContact CE1-CG 4.05Å; Y264-L268 HydrophobicContact CE2-CD2 4.22Å; Y264-L268 HydrophobicContact CE2-CG 4.17Å; Y264-L268 WeakPolarHBondContact O-CG 3.36Å; Y264-L268 PolarHBondContact O-N 2.97Å; S266-L268 PolarHBondContact O-N 2.46Å; L268-D272 VanDerWaalsContact O-CB 3.26Å; L268-D272 WeakPolarHBondContact O-CB 3.43Å; L268-D272 PolarHBondContact O-N 2.91Å; L268-H345 HydrophobicContact CD1-CB 4.12Å; L268-H345 WeakPolarHBondContact CD1-ND1 3.34Å; L268-Y348 HydrophobicContact CB-CD1 4.06Å; L268-Y348 HydrophobicContact CB-CD2 3.53Å; L268-Y348 HydrophobicContact CB-CE1 4.4Å; L268-Y348 HydrophobicContact CB-CE2 3.89Å; L268-Y348 HydrophobicContact CB-CG 3.63Å; L268-Y348 HydrophobicContact CD1-CD1 3.7Å; L268-Y348 HydrophobicContact CD1-CE1 4.31Å; L268-Y348 HydrophobicContact CD1-CG 3.88Å; L268-Y348 HydrophobicContact CG-CG 4.44Å
269L98.6Very high97.7Very high1 Ų131.1 Ų31.11%0.00518%0.182CC..Hα-helixtrans-74.2-33.7179.4-168.260.8000112.6M239 A265 S266 Y267 K273 F284 A286 F288 Y348 K352M239-L269 HydrophobicContact CB-CD2 4.28Å; M239-L269 HydrophobicContact CE-CD2 3.14Å; M239-L269 HydrophobicContact SD-CD2 3.47Å; M239-L269 WeakPolarHBondContact SD-CD2 3.47Å; A265-L269 PolarHBondContact O-N 3.38Å; S266-L269 PolarHBondContact O-N 2.94Å; Y267-L269 VanDerWaalsContact C-N 3.33Å; Y267-L269 PolarHBondContact O-N 3.48Å; L269-K273 HydrophobicContact CD1-CG 4.35Å; L269-K273 WeakPolarHBondContact O-CB 3.37Å; L269-K273 WeakPolarHBondContact O-CG 3.2Å; L269-K273 PolarHBondContact O-N 3.35Å; L269-F284 HydrophobicContact CD2-CE1 4.21Å; L269-F284 HydrophobicContact CG-CE1 4.05Å; L269-A286 HydrophobicContact CB-CB 3.81Å; L269-A286 HydrophobicContact CD2-CB 3.79Å; L269-A286 HydrophobicContact CG-CB 4.01Å; L269-F288 HydrophobicContact CB-CE2 4.27Å; L269-F288 HydrophobicContact CD2-CE2 4.28Å; L269-F288 HydrophobicContact CD2-CZ 4.4Å; L269-Y348 HydrophobicContact CB-CD2 3.95Å; L269-Y348 HydrophobicContact CB-CE2 4.3Å; L269-Y348 HydrophobicContact CD1-CD2 4.32Å; L269-Y348 HydrophobicContact CD1-CE2 4.08Å; L269-K352 HydrophobicContact CD1-CB 4.3Å
270E98.6Very high97.6Very high9 Ų932 Ų324%0.04219%0.193CC..Hα-helixtrans-68.8-45.8175.1-71177.9148.800111R53 R85 S266 Y267 D272 K273 N274 A286R53-E270 WeakPolarHBondContact CD-OE1 3.34Å; R53-E270 IonicContact CZ-OE1 2.9Å; R53-E270 IonicContact NH1-OE1 2.83Å; R53-E270 PolarHBondContact NH1-OE1 3.37Å; R53-E270 IonicContact NH1-OE2 3.43Å; R85-E270 IonicContact CZ-OE1 3.09Å; R85-E270 IonicContact CZ-OE2 3.57Å; R85-E270 IonicContact NE-OE1 3.25Å; R85-E270 PolarHBondContact NE-OE1 3.4Å; R85-E270 IonicContact NE-OE2 3.38Å; R85-E270 PolarHBondContact NE-OE2 3.2Å; R85-E270 IonicContact NH2-OE1 3.44Å; R85-E270 IonicContact NH2-OE2 2.8Å; R85-E270 PolarHBondContact NH2-OE2 2.72Å; S266-E270 WeakPolarHBondContact O-CG 2.95Å; S266-E270 PolarHBondContact O-N 3.43Å; Y267-E270 PolarHBondContact O-N 2.78Å; E270-D272 VanDerWaalsContact C-N 3.34Å; E270-D272 PolarHBondContact O-N 2.97Å; E270-K273 PolarHBondContact O-N 3.24Å; E270-N274 VanDerWaalsContact O-CB 3.24Å; E270-N274 WeakPolarHBondContact O-CB 3.36Å; E270-N274 PolarHBondContact O-N 3.45Å; E270-N274 PolarHBondContact O-ND2 3.04Å; E270-N274 VanDerWaalsContact O-ND2 3.07Å; E270-A286 HydrophobicContact CG-CB 3.73Å; E270-A286 PolarHBondContact OE1-N 3.49Å; E270-A286 VanDerWaalsContact OE1-N 3.09Å
271E96.6Very high97.4Very high65 Ų6536.7 Ų36.730%0.30421%0.214SC..Hα-helixtrans-55.6-47.9173.2-75.5-72.3111.900111.6Y267 K273 N274 P279Y267-E271 HydrophobicContact CD1-CG 4.33Å; Y267-E271 HydrophobicContact CD2-CG 4.39Å; Y267-E271 HydrophobicContact CE1-CG 4.06Å; Y267-E271 HydrophobicContact CE2-CG 4.16Å; Y267-E271 HydrophobicContact CG-CG 4.48Å; Y267-E271 WeakPolarHBondContact O-CB 3.25Å; Y267-E271 VanDerWaalsContact O-CG 3.32Å; Y267-E271 WeakPolarHBondContact O-CG 3.46Å; Y267-E271 PolarHBondContact O-N 2.85Å; E271-K273 PolarHBondContact O-N 3.25Å; E271-N274 CarbonylContact O-C 3.59Å; E271-N274 PolarHBondContact O-N 2.98Å; E271-P279 WeakPolarHBondContact OE1-CD 3.4Å; E271-P279 WeakPolarHBondContact OE1-CG 3.41Å
272D96.2Very high97.3Very high71 Ų7137.8 Ų37.838%0.3823%0.226SC..Hα-helixtrans-58.5-33.7178.1-97.522.8000114.6L268 E270 Y348 K352L268-D272 VanDerWaalsContact O-CB 3.26Å; L268-D272 WeakPolarHBondContact O-CB 3.43Å; L268-D272 PolarHBondContact O-N 2.91Å; E270-D272 VanDerWaalsContact C-N 3.34Å; E270-D272 PolarHBondContact O-N 2.97Å; D272-Y348 PolarHBondContact OD1-OH 3.25Å; D272-Y348 WeakPolarHBondContact OD2-CE2 3.35Å; D272-Y348 VanDerWaalsContact OD2-CZ 3.28Å; D272-Y348 PolarHBondContact OD2-OH 3.26Å; D272-K352 WeakPolarHBondContact OD2-CD 3.49Å; D272-K352 WeakPolarHBondContact OD2-CE 3.47Å; D272-K352 IonicContact OD2-NZ 3.33Å; D272-K352 PolarHBondContact OD2-NZ 2.75Å
273K96.8Very high97.2Very high93 Ų9342.8 Ų42.840%0.40426%0.261SS..Hα-helixtrans-101.4-12.2-172.9-71.9-67.4-172.5-177.90113.4L269 E270 E271 P275 F284L269-K273 HydrophobicContact CD1-CG 4.35Å; L269-K273 WeakPolarHBondContact O-CB 3.37Å; L269-K273 WeakPolarHBondContact O-CG 3.2Å; L269-K273 PolarHBondContact O-N 3.35Å; E270-K273 PolarHBondContact O-N 3.24Å; E271-K273 PolarHBondContact O-N 3.25Å; K273-P275 WeakPolarHBondContact O-CD 3.25Å; K273-F284 HydrophobicContact CB-CB 3.72Å; K273-F284 HydrophobicContact CB-CD1 3.48Å; K273-F284 VanDerWaalsContact CB-CD1 3.48Å; K273-F284 HydrophobicContact CB-CD2 3.92Å; K273-F284 HydrophobicContact CB-CE1 4.02Å; K273-F284 HydrophobicContact CB-CE2 4.4Å; K273-F284 HydrophobicContact CB-CG 3.42Å; K273-F284 VanDerWaalsContact CB-CG 3.42Å; K273-F284 HydrophobicContact CB-CZ 4.45Å; K273-F284 HydrophobicContact CD-CD2 4.48Å; K273-F284 HydrophobicContact CD-CE2 4.39Å; K273-F284 HydrophobicContact CG-CD1 3.82Å; K273-F284 HydrophobicContact CG-CD2 4.12Å; K273-F284 HydrophobicContact CG-CE1 3.81Å; K273-F284 HydrophobicContact CG-CE2 4.1Å; K273-F284 HydrophobicContact CG-CG 3.98Å; K273-F284 HydrophobicContact CG-CZ 3.95Å
274N97.1Very high97.2Very high11 Ų1143 Ų436%0.05926%0.262CS..SBendtrans-119.662.3176.3-60.9-50.7000109.9E270 E271 G276 E277 S283 F284E270-N274 VanDerWaalsContact O-CB 3.24Å; E270-N274 WeakPolarHBondContact O-CB 3.36Å; E270-N274 PolarHBondContact O-N 3.45Å; E270-N274 PolarHBondContact O-ND2 3.04Å; E270-N274 VanDerWaalsContact O-ND2 3.07Å; E271-N274 CarbonylContact O-C 3.59Å; E271-N274 PolarHBondContact O-N 2.98Å; N274-G276 PolarHBondContact O-N 2.78Å; N274-E277 HydrophobicContact CB-CB 4Å; N274-E277 HydrophobicContact CB-CG 4.01Å; N274-E277 WeakPolarHBondContact O-CB 3.31Å; N274-E277 PolarHBondContact O-N 3.12Å; N274-E277 VanDerWaalsContact O-N 3.16Å; N274-S283 PolarHBondContact OD1-N 3.15Å; N274-F284 PolarHBondContact ND2-O 3.16Å; N274-F284 VanDerWaalsContact OD1-CB 3.24Å; N274-F284 WeakPolarHBondContact OD1-CB 3.4Å; N274-F284 PolarHBondContact OD1-N 2.7Å
275P95.3Very high97.2Very high111 Ų11142.4 Ų42.472%0.72126%0.26SS*.THydrogen-bonded Turntrans-61.6129.1-175.527.4-35.6000111.2K273 E277K273-P275 WeakPolarHBondContact O-CD 3.25Å; P275-E277 VanDerWaalsContact C-N 3.32Å
276G93.5Very high97.2Very high90 Ų9042.4 Ų42.493%0.92826%0.26SS*.THydrogen-bonded Turntrans87-4.2179.100000114.8N274N274-G276 PolarHBondContact O-N 2.78Å
277E97.1Very high97.1Very high89 Ų8942.4 Ų42.442%0.41626%0.26SS..PPolyproline II helixtrans-87.3151.2172-61.6-71.4153.100110.2N274 P275 Q281 G282N274-E277 HydrophobicContact CB-CB 4Å; N274-E277 HydrophobicContact CB-CG 4.01Å; N274-E277 WeakPolarHBondContact O-CB 3.31Å; N274-E277 PolarHBondContact O-N 3.12Å; N274-E277 VanDerWaalsContact O-N 3.16Å; P275-E277 VanDerWaalsContact C-N 3.32Å; E277-Q281 HydrophobicContact CB-CB 4.24Å; E277-G282 PolarHBondContact OE2-N 2.89Å
278L97.3Very high97.1Very high34 Ų3441.3 Ų41.318%0.17826%0.255CS..PPolyproline II helixtrans-75.7154.4172.3-73.3170.2000111.1G280 Q281 V652L278-G280 PolarHBondContact O-N 3.12Å; L278-Q281 HydrophobicContact CB-CG 4.33Å; L278-Q281 WeakPolarHBondContact O-CA 3.14Å; L278-Q281 VanDerWaalsContact O-CB 3.23Å; L278-Q281 WeakPolarHBondContact O-CB 3.38Å; L278-Q281 PolarHBondContact O-N 3.41Å; L278-V652 HydrophobicContact CD1-CB 4.1Å; L278-V652 HydrophobicContact CD1-CG1 3.69Å; L278-V652 HydrophobicContact CD2-CG1 4.15Å
279P97Very high97.1Very high8 Ų840.1 Ų40.15%0.05225%0.249CC..THydrogen-bonded Turntrans-49.5129.2171.8-33.638.4000113.2Y267 E271 N655 A657 S658Y267-P279 HydrophobicContact CD2-CB 4.16Å; Y267-P279 HydrophobicContact CD2-CG 4.47Å; Y267-P279 HydrophobicContact CE2-CB 3.61Å; Y267-P279 HydrophobicContact CE2-CG 3.52Å; E271-P279 WeakPolarHBondContact OE1-CD 3.4Å; E271-P279 WeakPolarHBondContact OE1-CG 3.41Å; P279-N655 PolarHBondContact O-ND2 2.79Å; P279-N655 VanDerWaalsContact O-ND2 3.12Å; P279-A657 HydrophobicContact CB-CB 3.96Å; P279-S658 WeakPolarHBondContact CG-OG 3.37Å
280G96.2Very high97Very high26 Ų2640.1 Ų40.127%0.26825%0.249SC..THydrogen-bonded Turntrans90.7-9.2-173.700000114.8R53 Y83 L278R53-G280 PolarHBondContact NE-O 3.21Å; R53-G280 VanDerWaalsContact NH2-C 3.28Å; R53-G280 PolarHBondContact NH2-O 2.77Å; Y83-G280 VanDerWaalsContact OH-CA 3.3Å; Y83-G280 WeakPolarHBondContact OH-CA 3.49Å; L278-G280 PolarHBondContact O-N 3.12Å
281Q96.3Very high97Very high97 Ų9740 Ų4045%0.45325%0.25SC..  trans-107.1-178.4178.1-51.9-176.614.400112R53 E277 L278R53-Q281 PolarHBondContact NH2-O 3.34Å; E277-Q281 HydrophobicContact CB-CB 4.24Å; L278-Q281 HydrophobicContact CB-CG 4.33Å; L278-Q281 WeakPolarHBondContact O-CA 3.14Å; L278-Q281 VanDerWaalsContact O-CB 3.23Å; L278-Q281 WeakPolarHBondContact O-CB 3.38Å; L278-Q281 PolarHBondContact O-N 3.41Å
282G96.3Very high97.1Very high24 Ų2437 Ų3725%0.24724%0.235CC..SBendtrans81158.3-173.200000115.4R53 E277R53-G282 PolarHBondContact NH2-O 2.78Å; E277-G282 PolarHBondContact OE2-N 2.89Å
283S95.8Very high97.3Very high105 Ų10533.6 Ų33.673%0.73422%0.217SC*.SBendtrans-84.2-25.2-170.954.20000114.8N274N274-S283 PolarHBondContact OD1-N 3.15Å
284F98.1Very high97.3Very high5 Ų529.1 Ų29.12%0.02220%0.198CC..  trans-73.2135.7176.9-171.9-88.8000110.4R53 G236 I237 G238 M239 L269 K273 N274 A286 Y355R53-F284 PolarHBondContact NH1-O 3.09Å; G236-F284 WeakPolarHBondContact O-CD2 3.32Å; I237-F284 WeakPolarHBondContact O-CA 3.47Å; G238-F284 VanDerWaalsContact CA-CE2 3.49Å; M239-F284 HydrophobicContact CB-CZ 4.11Å; L269-F284 HydrophobicContact CD2-CE1 4.21Å; L269-F284 HydrophobicContact CG-CE1 4.05Å; K273-F284 HydrophobicContact CB-CB 3.72Å; K273-F284 HydrophobicContact CB-CD1 3.48Å; K273-F284 VanDerWaalsContact CB-CD1 3.48Å; K273-F284 HydrophobicContact CB-CD2 3.92Å; K273-F284 HydrophobicContact CB-CE1 4.02Å; K273-F284 HydrophobicContact CB-CE2 4.4Å; K273-F284 HydrophobicContact CB-CG 3.42Å; K273-F284 VanDerWaalsContact CB-CG 3.42Å; K273-F284 HydrophobicContact CB-CZ 4.45Å; K273-F284 HydrophobicContact CD-CD2 4.48Å; K273-F284 HydrophobicContact CD-CE2 4.39Å; K273-F284 HydrophobicContact CG-CD1 3.82Å; K273-F284 HydrophobicContact CG-CD2 4.12Å; K273-F284 HydrophobicContact CG-CE1 3.81Å; K273-F284 HydrophobicContact CG-CE2 4.1Å; K273-F284 HydrophobicContact CG-CG 3.98Å; K273-F284 HydrophobicContact CG-CZ 3.95Å; N274-F284 PolarHBondContact ND2-O 3.16Å; N274-F284 VanDerWaalsContact OD1-CB 3.24Å; N274-F284 WeakPolarHBondContact OD1-CB 3.4Å; N274-F284 PolarHBondContact OD1-N 2.7Å; F284-A286 HydrophobicContact CE1-CB 4.03Å; F284-Y355 HydrophobicContact CE2-CE2 4.29Å; F284-Y355 HydrophobicContact CZ-CE2 4.06Å
285V98.8Very high97.4Very high4 Ų428.8 Ų28.82%0.02420%0.196CC..EExtended strand (participates in β ladder)trans-121.6124.9179.6-1770000110.7V51 R53 R85 F87 I237 G238 M239V51-V285 HydrophobicContact CB-CB 4.15Å; V51-V285 HydrophobicContact CB-CG2 4.08Å; V51-V285 HydrophobicContact CG2-CB 4.49Å; V51-V285 HydrophobicContact CG2-CG2 4.12Å; R53-V285 HydrophobicContact CB-CG1 4.29Å; R53-V285 HydrophobicContact CB-CG2 4.1Å; R85-V285 HydrophobicContact CB-CG1 3.74Å; R85-V285 HydrophobicContact CG-CG1 3.79Å; F87-V285 HydrophobicContact CE1-CG1 4.43Å; F87-V285 HydrophobicContact CZ-CG1 3.93Å; I237-V285 PolarHBondContact O-N 2.74Å; G238-V285 CarbonylContact C-O 3.57Å; G238-V285 WeakPolarHBondContact CA-O 3.48Å; M239-V285 PolarHBondContact N-O 3.22Å
286A98.7Very high97.6Very high0 Ų023.5 Ų23.50%016%0.162CC..EExtended strand (participates in β ladder)trans-115.3104.317800000111.7R85 S266 L269 E270 F284 F288R85-A286 WeakPolarHBondContact CD-O 3.16Å; R85-A286 PolarHBondContact NE-O 2.81Å; R85-A286 VanDerWaalsContact NE-O 3.12Å; S266-A286 WeakPolarHBondContact CB-O 3.37Å; S266-A286 PolarHBondContact OG-O 2.98Å; L269-A286 HydrophobicContact CB-CB 3.81Å; L269-A286 HydrophobicContact CD2-CB 3.79Å; L269-A286 HydrophobicContact CG-CB 4.01Å; E270-A286 HydrophobicContact CG-CB 3.73Å; E270-A286 PolarHBondContact OE1-N 3.49Å; E270-A286 VanDerWaalsContact OE1-N 3.09Å; F284-A286 HydrophobicContact CE1-CB 4.03Å; A286-F288 HydrophobicContact CB-CE2 4.21Å
287G98.6Very high97.8Very high0 Ų019.2 Ų19.20%012%0.117CC..EExtended strand (participates in β ladder)trans-93.1117.2176.300000112.1M239 I240 S241M239-G287 PolarHBondContact O-N 2.87Å; I240-G287 CarbonylContact C-O 3.56Å; I240-G287 VanDerWaalsContact CA-O 3.26Å; I240-G287 WeakPolarHBondContact CA-O 3.1Å; S241-G287 PolarHBondContact N-O 2.91Å
288F98.8Very high97.9Very high0 Ų015 Ų150%010%0.098CC..EExtended strand (participates in β ladder)trans-102.9107.6168.7-73.9-103.9000109.5T136 M239 M262 A265 S266 L269 A286 I347 A351T136-F288 WeakPolarHBondContact CG2-O 3.46Å; M239-F288 HydrophobicContact CE-CD2 4.34Å; M239-F288 HydrophobicContact CE-CE1 4.19Å; M239-F288 HydrophobicContact CE-CE2 3.64Å; M239-F288 HydrophobicContact CE-CZ 3.56Å; M262-F288 HydrophobicContact CB-CB 4.4Å; M262-F288 HydrophobicContact CE-CB 3.94Å; A265-F288 VanDerWaalsContact C-CE2 3.47Å; A265-F288 HydrophobicContact CB-CD1 3.82Å; A265-F288 HydrophobicContact CB-CD2 4.18Å; A265-F288 HydrophobicContact CB-CE1 3.76Å; A265-F288 HydrophobicContact CB-CE2 4.09Å; A265-F288 HydrophobicContact CB-CG 4.02Å; A265-F288 HydrophobicContact CB-CZ 3.87Å; A265-F288 VanDerWaalsContact O-CE2 3.31Å; A265-F288 WeakPolarHBondContact O-CE2 3.3Å; S266-F288 VanDerWaalsContact OG-CD2 3.25Å; S266-F288 WeakPolarHBondContact OG-CD2 3.48Å; L269-F288 HydrophobicContact CB-CE2 4.27Å; L269-F288 HydrophobicContact CD2-CE2 4.28Å; L269-F288 HydrophobicContact CD2-CZ 4.4Å; A286-F288 HydrophobicContact CB-CE2 4.21Å; F288-I347 HydrophobicContact CD1-CG2 3.55Å; F288-I347 HydrophobicContact CE1-CG2 3.55Å; F288-A351 HydrophobicContact CE1-CB 3.48Å; F288-A351 VanDerWaalsContact CE1-CB 3.48Å; F288-A351 HydrophobicContact CZ-CB 3.62Å
289S97.9Very high98Very high0 Ų013.7 Ų13.70%09%0.091CC..EExtended strand (participates in β ladder)trans-96.6147.7-174.7-176.40000112.2S241 W242 M262S241-S289 PolarHBondContact O-N 3.43Å; W242-S289 PolarHBondContact NE1-OG 3.48Å; M262-S289 WeakPolarHBondContact CE-O 3.35Å
290S96.9Very high98Very high0 Ų015.1 Ų15.10%010%0.1CC..EExtended strand (participates in β ladder)trans-62.6153.3166.6600000111.7G135 L293 G515 L516G135-S290 WeakPolarHBondContact O-CB 3.5Å; G135-S290 PolarHBondContact O-OG 3.31Å; S290-L293 VanDerWaalsContact CB-CD2 3.48Å; S290-G515 PolarHBondContact O-N 2.92Å; S290-G515 PolarHBondContact OG-O 3.16Å; S290-G515 VanDerWaalsContact OG-O 3.1Å; S290-L516 WeakPolarHBondContact OG-CD1 3.32Å
291S98.7Very high98Very high8 Ų820.4 Ų20.46%0.05611%0.111CC..  trans-125.6-141.6174.2-1720000109.8L293 I513S291-L293 VanDerWaalsContact C-N 3.29Å; S291-L293 PolarHBondContact O-N 3.44Å; S291-L293 VanDerWaalsContact O-N 3.09Å; S291-I513 WeakPolarHBondContact CA-O 3.49Å; S291-I513 PolarHBondContact OG-O 3.24Å
292N98.8Very high98Very high0 Ų016.2 Ų16.20%010%0.095CC..SBendtrans-8468.9173.760.7-58.6000112D221 M484 T485 T486 R493 I513D221-N292 PolarHBondContact OD2-ND2 2.82Å; D221-N292 PolarHBondContact OD2-OD1 2.79Å; N292-M484 CarbonylContact C-O 3.59Å; N292-M484 VanDerWaalsContact CA-O 3.3Å; N292-M484 WeakPolarHBondContact CA-O 3.15Å; N292-M484 HydrophobicContact CB-CB 3.88Å; N292-T485 PolarHBondContact ND2-O 3.43Å; N292-T486 WeakPolarHBondContact ND2-CA 3.42Å; N292-T486 PolarHBondContact ND2-O 2.64Å; N292-T486 VanDerWaalsContact ND2-O 3.1Å; N292-R493 PolarHBondContact OD1-NH1 2.62Å; N292-I513 HydrophobicContact CB-CG2 4.38Å
293L98.7Very high98Very high0 Ų017.4 Ų17.40%010%0.098CC..  trans-86.5-0.1-172.454.974.7000115.2H137 V245 H246 S290 S291 D295 V296 E483 M484 L516H137-L293 HydrophobicContact CB-CD2 4.08Å; V245-L293 WeakPolarHBondContact O-CD2 3.37Å; H246-L293 WeakPolarHBondContact CE1-CD1 3.21Å; H246-L293 PolarHBondContact CE1-O 2.92Å; H246-L293 PolarHBondContact ND1-O 2.92Å; S290-L293 VanDerWaalsContact CB-CD2 3.48Å; S291-L293 VanDerWaalsContact C-N 3.29Å; S291-L293 PolarHBondContact O-N 3.44Å; S291-L293 VanDerWaalsContact O-N 3.09Å; L293-D295 VanDerWaalsContact C-N 3.26Å; L293-D295 PolarHBondContact O-N 3.02Å; L293-V296 PolarHBondContact O-N 2.65Å; L293-E483 HydrophobicContact CD1-CG 4.08Å; L293-M484 PolarHBondContact N-O 3.34Å; L293-L516 HydrophobicContact CD1-CD1 4.21Å; L293-L516 HydrophobicContact CD2-CD1 4.08Å; L293-L516 HydrophobicContact CG-CD1 4.29Å
294G98.7Very high98Very high0 Ų016.4 Ų16.40%08%0.079CC..THydrogen-bonded Turntrans-55.2-30-162.300000116.7R200 M484 Y523 E536R200-G294 PolarHBondContact NE-O 2.96Å; R200-G294 PolarHBondContact NH2-O 3.39Å; G294-M484 WeakPolarHBondContact CA-O 3.28Å; G294-M484 PolarHBondContact N-O 3.24Å; G294-Y523 WeakPolarHBondContact O-CE1 3.45Å; G294-E536 VanDerWaalsContact O-CG 3.28Å; G294-E536 WeakPolarHBondContact O-CG 3.43Å
295D98.8Very high98Very high3 Ų316.2 Ų16.22%0.0168%0.078CC..THydrogen-bonded Turntrans-116.422.8176.463-20.4000112.9N199 R200 L293 T485 T486N199-D295 CarbonylContact C-O 3.58Å; N199-D295 VanDerWaalsContact CA-O 3.25Å; N199-D295 WeakPolarHBondContact CA-O 3.35Å; N199-D295 PolarHBondContact ND2-OD2 2.58Å; N199-D295 PolarHBondContact OD1-O 3.01Å; R200-D295 PolarHBondContact N-O 2.85Å; L293-D295 VanDerWaalsContact C-N 3.26Å; L293-D295 PolarHBondContact O-N 3.02Å; D295-T485 HydrophobicContact CB-CG2 4.08Å; D295-T485 WeakPolarHBondContact OD1-CA 3.32Å; D295-T486 WeakPolarHBondContact OD1-CB 3.31Å; D295-T486 PolarHBondContact OD1-N 3.24Å; D295-T486 PolarHBondContact OD1-OG1 3.41Å
296V98.8Very high97.8Very high0 Ų018.8 Ų18.80%09%0.093CC..EExtended strand (participates in β ladder)trans-121.2108.2-169.5-167.10000112.6L198 T220 A244 H246 L293 T486L198-V296 CarbonylContact O-C 3.45Å; L198-V296 WeakPolarHBondContact O-CA 3.48Å; T220-V296 HydrophobicContact CG2-CG1 3.83Å; T220-V296 HydrophobicContact CG2-CG2 4.15Å; A244-V296 WeakPolarHBondContact O-CG1 3.41Å; H246-V296 WeakPolarHBondContact CB-O 3.17Å; H246-V296 PolarHBondContact N-O 3.34Å; H246-V296 PolarHBondContact ND1-O 2.79Å; L293-V296 PolarHBondContact O-N 2.65Å; V296-T486 WeakPolarHBondContact CG2-OG1 3.38Å
297T98.8Very high97.5Very high0 Ų022.1 Ų22.10%011%0.111CC..EExtended strand (participates in β ladder)trans-95.9145.3179.6177.30000112.9S197 L198 R200 N299 I404 D405S197-T297 CarbonylContact C-O 3.09Å; S197-T297 WeakPolarHBondContact CA-O 3.3Å; L198-T297 HydrophobicContact CB-CG2 3.91Å; L198-T297 HydrophobicContact CD2-CG2 4.15Å; L198-T297 PolarHBondContact N-O 3.06Å; L198-T297 WeakPolarHBondContact O-CG2 3.36Å; L198-T297 PolarHBondContact O-N 3.42Å; R200-T297 HydrophobicContact CB-CG2 3.93Å; T297-N299 VanDerWaalsContact OG1-CB 3.3Å; T297-N299 WeakPolarHBondContact OG1-CB 3.33Å; T297-N299 PolarHBondContact OG1-N 3.38Å; T297-N299 PolarHBondContact OG1-ND2 2.88Å; T297-I404 HydrophobicContact CG2-CD1 4.43Å; T297-D405 VanDerWaalsContact CB-OD1 3.26Å; T297-D405 WeakPolarHBondContact CB-OD1 3.25Å; T297-D405 WeakPolarHBondContact CB-OD2 2.71Å; T297-D405 VanDerWaalsContact OG1-CG 3.31Å; T297-D405 PolarHBondContact OG1-OD1 3.32Å
298P98.6Very high97.4Very high0 Ų025.5 Ų25.50%013%0.132CC..SBendtrans-78.4-6.2167.435.9-38.3000112.9V245 H246 V248 S249 N261 T300 I343V245-P298 HydrophobicContact CG2-CB 3.72Å; V245-P298 HydrophobicContact CG2-CG 4.41Å; H246-P298 VanDerWaalsContact O-CD 3.31Å; H246-P298 WeakPolarHBondContact O-CD 3.26Å; H246-P298 VanDerWaalsContact O-CG 3.3Å; H246-P298 WeakPolarHBondContact O-CG 3.5Å; V248-P298 VanDerWaalsContact CG2-CD 3.4Å; V248-P298 HydrophobicContact CG2-CG 3.7Å; S249-P298 WeakPolarHBondContact OG-CB 3.44Å; S249-P298 WeakPolarHBondContact OG-CG 3.28Å; N261-P298 WeakPolarHBondContact ND2-CB 3.42Å; P298-T300 VanDerWaalsContact C-N 3.28Å; P298-T300 PolarHBondContact O-N 2.94Å; P298-I343 HydrophobicContact CB-CG1 4.21Å; P298-I343 HydrophobicContact CB-CG2 3.94Å; P298-I343 WeakPolarHBondContact O-CD1 3.35Å
299N98.4Very high97.2Very high8 Ų828.2 Ų28.24%0.04316%0.16CC..  trans-8272.1-175.4-66.3-45.1000111.2T297 R301 G302 A329 F330 G331 D405T297-N299 VanDerWaalsContact OG1-CB 3.3Å; T297-N299 WeakPolarHBondContact OG1-CB 3.33Å; T297-N299 PolarHBondContact OG1-N 3.38Å; T297-N299 PolarHBondContact OG1-ND2 2.88Å; N299-R301 VanDerWaalsContact C-N 3.3Å; N299-R301 PolarHBondContact O-N 3.1Å; N299-G302 PolarHBondContact O-N 3.03Å; N299-G302 VanDerWaalsContact O-N 3.15Å; N299-A329 HydrophobicContact CB-CB 3.64Å; N299-F330 CarbonylContact C-O 3.5Å; N299-F330 WeakPolarHBondContact CA-O 3.14Å; N299-G331 PolarHBondContact OD1-N 2.86Å; N299-G331 VanDerWaalsContact OD1-N 3.11Å; N299-D405 PolarHBondContact ND2-OD1 2.9Å
300T97.8Very high97.1Very high37 Ų3732.8 Ų32.823%0.22718%0.184CC..THydrogen-bonded Turntrans-72.2-9.7-165.954.50000116P298 G302 F330 I343P298-T300 VanDerWaalsContact C-N 3.28Å; P298-T300 PolarHBondContact O-N 2.94Å; T300-G302 PolarHBondContact O-N 3.23Å; T300-F330 PolarHBondContact N-O 2.79Å; T300-I343 HydrophobicContact CG2-CD1 4.24Å
301R96.7Very high97Very high137 Ų13738 Ų3852%0.51722%0.218SC..THydrogen-bonded Turntrans-71.5-13.4170-63.6-177.4177.41512.5112.7N299 F330 G331 P332 G333N299-R301 VanDerWaalsContact C-N 3.3Å; N299-R301 PolarHBondContact O-N 3.1Å; R301-F330 VanDerWaalsContact CB-O 3.28Å; R301-F330 WeakPolarHBondContact CB-O 3.13Å; R301-F330 PolarHBondContact N-O 2.95Å; R301-G331 WeakPolarHBondContact CD-O 3.46Å; R301-G331 WeakPolarHBondContact CG-O 3.42Å; R301-G331 VanDerWaalsContact CZ-O 3.24Å; R301-G331 PolarHBondContact NE-O 2.81Å; R301-G331 VanDerWaalsContact NE-O 3.15Å; R301-G331 PolarHBondContact NH1-O 3.35Å; R301-P332 PolarHBondContact NH2-O 3.33Å; R301-G333 PolarHBondContact NH1-O 3.2Å; R301-G333 PolarHBondContact NH2-O 3.45Å
302G95.5Very high96.8Very high10 Ų1038.5 Ų38.510%0.10322%0.221CC..  trans76.2171.5179.300000113.5N299 T300 A329N299-G302 PolarHBondContact O-N 3.03Å; N299-G302 VanDerWaalsContact O-N 3.15Å; T300-G302 PolarHBondContact O-N 3.23Å; G302-A329 WeakPolarHBondContact O-CA 3.41Å
303P96.3Very high96.6Very high49 Ų4941.6 Ų41.632%0.31824%0.238SC..EExtended strand (participates in β ladder)trans-83.1134.6-171.832.1-34.7000113.3C312 Q328 A329 I404P303-C312 HydrophobicContact CB-CB 4.4Å; P303-Q328 WeakPolarHBondContact CA-O 3.49Å; P303-A329 HydrophobicContact CB-CB 4.33Å; P303-I404 HydrophobicContact CB-CB 4Å; P303-I404 HydrophobicContact CB-CD1 4.02Å; P303-I404 HydrophobicContact CB-CG2 3.76Å; P303-I404 HydrophobicContact CG-CD1 3.99Å; P303-I404 HydrophobicContact CG-CG2 4.33Å
304Y96.6Very high96.3Very high84 Ų8447.6 Ų47.633%0.32926%0.261SS..EExtended strand (participates in β ladder)trans-143.2165.5169.263.3-89.6000111.3V306 C312 Q328 F330Y304-V306 HydrophobicContact CE2-CG1 4.31Å; Y304-V306 PolarHBondContact O-N 2.73Å; Y304-C312 VanDerWaalsContact C-SG 3.52Å; Y304-Q328 PolarHBondContact N-O 3.25Å; Y304-Q328 PolarHBondContact O-N 3.31Å; Y304-F330 HydrophobicContact CD1-CD2 4.44Å; Y304-F330 AromaticContact CE1-CD2 3.47Å; Y304-F330 HydrophobicContact CE1-CD2 3.47Å; Y304-F330 VanDerWaalsContact CE1-CD2 3.47Å; Y304-F330 AromaticContact CE1-CE2 3.96Å; Y304-F330 HydrophobicContact CE1-CE2 3.96Å; Y304-F330 HydrophobicContact CE1-CG 4.49Å; Y304-F330 HydrophobicContact CE2-CE2 4.22Å; Y304-F330 AromaticContact CZ-CD2 3.5Å; Y304-F330 AromaticContact CZ-CE2 3.58Å; Y304-F330 VanDerWaalsContact OH-CD2 3.23Å; Y304-F330 WeakPolarHBondContact OH-CD2 3.3Å; Y304-F330 WeakPolarHBondContact OH-CE2 3.44Å
305C96.4Very high95.9Very high0 Ų051.1 Ų51.10%028%0.28CS..EExtended strand (participates in β ladder)trans-76.8107176.2-63.70000110.4N307 T308 G309 L310 C319 M326C305-N307 PolarHBondContact O-N 3.34Å; C305-T308 VanDerWaalsContact CB-OG1 3.24Å; C305-T308 WeakPolarHBondContact CB-OG1 3.35Å; C305-T308 PolarHBondContact O-N 3.36Å; C305-T308 VanDerWaalsContact O-N 3.13Å; C305-G309 WeakPolarHBondContact O-CA 3.38Å; C305-G309 PolarHBondContact O-N 3.03Å; C305-L310 WeakPolarHBondContact CB-O 3.1Å; C305-L310 PolarHBondContact N-O 3.09Å; C305-C319 WeakPolarHBondContact CA-SG 3.48Å; C305-C319 HydrophobicContact CB-CB 3.87Å; C305-C319 WeakPolarHBondContact CB-SG 3.47Å; C305-C319 VanDerWaalsContact SG-CA 3.54Å; C305-C319 WeakPolarHBondContact SG-CB 3.33Å; C305-C319 CovalentContact SG-SG 2.03Å; C305-C319 PolarHBondContact SG-SG 2.93Å; C305-M326 CarbonylContact C-O 3.59Å; C305-M326 WeakPolarHBondContact CA-O 3.46Å
306V94.6Very high95.5Very high58 Ų5853.7 Ų53.735%0.35229%0.293SS..THydrogen-bonded Turntrans-61-23.2-172.3-60.60000114.3Y304 M326 Q328 F330Y304-V306 HydrophobicContact CE2-CG1 4.31Å; Y304-V306 PolarHBondContact O-N 2.73Å; V306-M326 HydrophobicContact CG2-CB 4.3Å; V306-M326 HydrophobicContact CG2-SD 3.56Å; V306-M326 VanDerWaalsContact CG2-SD 3.56Å; V306-M326 PolarHBondContact N-O 2.62Å; V306-Q328 HydrophobicContact CG1-CB 3.77Å; V306-Q328 HydrophobicContact CG1-CG 3.96Å; V306-F330 HydrophobicContact CG1-CE2 3.59Å; V306-F330 HydrophobicContact CG1-CZ 3.75Å
307N94.3Very high95.4Very high70 Ų7054.1 Ų54.137%0.37430%0.297SS..THydrogen-bonded Turntrans-89-25-179.857.6-12.7000114.2C305 V321 M326C305-N307 PolarHBondContact O-N 3.34Å; N307-V321 PolarHBondContact ND2-O 3.45Å; N307-M326 HydrophobicContact CB-SD 4.26Å
308T95.4Very high95.1Very high71 Ų7155.1 Ų55.144%0.43630%0.304SS..THydrogen-bonded Turntrans-122.1-16.8-174.362.50000114.1C305 L310C305-T308 VanDerWaalsContact CB-OG1 3.24Å; C305-T308 WeakPolarHBondContact CB-OG1 3.35Å; C305-T308 PolarHBondContact O-N 3.36Å; C305-T308 VanDerWaalsContact O-N 3.13Å; T308-L310 PolarHBondContact O-N 2.97Å; T308-L310 PolarHBondContact OG1-N 3.35Å
309G94.6Very high94.9Very high57 Ų5755.4 Ų55.459%0.58831%0.305SS*.  trans73.61.6-172.300000114.6C305C305-G309 WeakPolarHBondContact O-CA 3.38Å; C305-G309 PolarHBondContact O-N 3.03Å
310L94.9Very high94.6Very high97 Ų9760.6 Ų60.651%0.50834%0.339SS..PPolyproline II helixtrans-73.8153.5178.9-64.7175.8000111.5C305 T308C305-L310 WeakPolarHBondContact CB-O 3.1Å; C305-L310 PolarHBondContact N-O 3.09Å; T308-L310 PolarHBondContact O-N 2.97Å; T308-L310 PolarHBondContact OG1-N 3.35Å
311P94.8Very high94.2Very high108 Ų10863.2 Ų63.270%0.70136%0.355SS*.BIsolated β-bridgetrans-57.6141.7168.9-21.933000111.2
312C95.4Very high93.7Very high19 Ų1958.6 Ų58.613%0.12835%0.351CS..PPolyproline II helixtrans-66.1156.9170.1-64.30000111.8P303 Y304 Y314 C327P303-C312 HydrophobicContact CB-CB 4.4Å; Y304-C312 VanDerWaalsContact C-SG 3.52Å; C312-Y314 PolarHBondContact O-N 2.85Å; C312-C327 HydrophobicContact CB-CB 4.03Å; C312-C327 WeakPolarHBondContact CB-SG 3.16Å; C312-C327 WeakPolarHBondContact SG-CA 3.45Å; C312-C327 WeakPolarHBondContact SG-CB 3.46Å; C312-C327 CovalentContact SG-SG 2.03Å; C312-C327 PolarHBondContact SG-SG 3.15Å
313D94.3Very high93.5Very high66 Ų6658.7 Ų58.735%0.35335%0.352SS..PPolyproline II helixtrans-58.8127.6166.8-178.2-103.9000111L315 N316 S317 S318D313-L315 VanDerWaalsContact C-N 3.34Å; D313-L315 PolarHBondContact O-N 3.49Å; D313-L315 PolarHBondContact OD1-N 3.31Å; D313-L315 VanDerWaalsContact OD1-N 3.17Å; D313-N316 WeakPolarHBondContact OD1-CB 3.26Å; D313-N316 PolarHBondContact OD1-N 3.09Å; D313-N316 PolarHBondContact OD1-ND2 2.94Å; D313-S317 VanDerWaalsContact O-CA 3.26Å; D313-S317 WeakPolarHBondContact O-CA 3.03Å; D313-S317 PolarHBondContact O-N 3.45Å; D313-S318 WeakPolarHBondContact CB-O 3.39Å; D313-S318 PolarHBondContact N-O 3.1Å
314Y92Very high93.1Very high126 Ų12656.6 Ų56.649%0.49434%0.338SS..THydrogen-bonded Turntrans-67.3-33.3-172.2177-111.9000113.2P202 H203 C312P202-Y314 HydrophobicContact CB-CE2 4.35Å; P202-Y314 HydrophobicContact CG-CE2 3.71Å; H203-Y314 HydrophobicContact CB-CD1 4.33Å; H203-Y314 HydrophobicContact CB-CE1 3.7Å; H203-Y314 AromaticContact CD2-CE1 3.65Å; H203-Y314 PolarHBondContact N-OH 3.13Å; C312-Y314 PolarHBondContact O-N 2.85Å
315L90.2Very high92.7Very high74 Ų7456.9 Ų56.939%0.38734%0.341SS..THydrogen-bonded Turntrans-86.6-42.9-175.9-65.3179.4000112H203 D313 R534H203-L315 HydrophobicContact CB-CD2 4.22Å; H203-L315 WeakPolarHBondContact CD2-CD2 3.41Å; H203-L315 WeakPolarHBondContact CE1-CD2 3.31Å; H203-L315 WeakPolarHBondContact ND1-CD2 3.45Å; H203-L315 VanDerWaalsContact NE2-CD2 3.33Å; H203-L315 WeakPolarHBondContact NE2-CD2 3.39Å; D313-L315 VanDerWaalsContact C-N 3.34Å; D313-L315 PolarHBondContact O-N 3.49Å; D313-L315 PolarHBondContact OD1-N 3.31Å; D313-L315 VanDerWaalsContact OD1-N 3.17Å; L315-R534 PolarHBondContact O-NH1 2.82Å
316N92.1Very high92.5Very high56 Ų5659.6 Ų59.630%0.29935%0.354SS..THydrogen-bonded Turntrans-105.5-11.8-166.8-59-35.5000113.3D313 S318 Q414D313-N316 WeakPolarHBondContact OD1-CB 3.26Å; D313-N316 PolarHBondContact OD1-N 3.09Å; D313-N316 PolarHBondContact OD1-ND2 2.94Å; N316-S318 VanDerWaalsContact C-N 3.31Å; N316-S318 PolarHBondContact O-N 3.14Å; N316-Q414 WeakPolarHBondContact CA-O 3.4Å; N316-Q414 PolarHBondContact O-N 3.45Å; N316-Q414 PolarHBondContact OD1-O 3.34Å; N316-Q414 VanDerWaalsContact OD1-O 3.08Å
317S94.8Very high92.6Very high10 Ų1056.8 Ų56.87%0.0734%0.337CS..  trans50.650.8-174.2-66.50000112.4D313 C327 R534D313-S317 VanDerWaalsContact O-CA 3.26Å; D313-S317 WeakPolarHBondContact O-CA 3.03Å; D313-S317 PolarHBondContact O-N 3.45Å; S317-C327 VanDerWaalsContact O-CB 3.23Å; S317-C327 WeakPolarHBondContact O-CB 3.44Å; S317-R534 PolarHBondContact OG-NH1 3.18Å; S317-R534 PolarHBondContact OG-NH2 2.89Å
318S93.8Very high92.7Very high21 Ų2154.6 Ų54.615%0.14733%0.325CS..  trans-127.8161.2-179.864.50000111.3D313 N316D313-S318 WeakPolarHBondContact CB-O 3.39Å; D313-S318 PolarHBondContact N-O 3.1Å; N316-S318 VanDerWaalsContact C-N 3.31Å; N316-S318 PolarHBondContact O-N 3.14Å
319C94.1Very high92.8Very high6 Ų651.6 Ų51.64%0.04131%0.307CS..BIsolated β-bridgetrans-110.8144.9175.8-68.60000110.9C305 V321 G323 M326C305-C319 WeakPolarHBondContact CA-SG 3.48Å; C305-C319 HydrophobicContact CB-CB 3.87Å; C305-C319 WeakPolarHBondContact CB-SG 3.47Å; C305-C319 VanDerWaalsContact SG-CA 3.54Å; C305-C319 WeakPolarHBondContact SG-CB 3.33Å; C305-C319 CovalentContact SG-SG 2.03Å; C305-C319 PolarHBondContact SG-SG 2.93Å; C319-V321 PolarHBondContact O-N 3.04Å; C319-G323 PolarHBondContact N-O 2.94Å; C319-G323 WeakPolarHBondContact O-CA 3.49Å; C319-G323 PolarHBondContact O-N 3.36Å; C319-M326 HydrophobicContact CB-CB 4.04Å
320P91.6Very high92.8Very high116 Ų11651.4 Ų51.475%0.75329%0.29SS*.THydrogen-bonded Turntrans-55.7-34.9176.8-26.534.3000113.2
321V90.3Very high92.9Very high92 Ų9246.9 Ų46.956%0.55827%0.267SS*.THydrogen-bonded Turntrans-114.9119174.5-177.20000108.4N307 C319N307-V321 PolarHBondContact ND2-O 3.45Å; C319-V321 PolarHBondContact O-N 3.04Å
322G86.9Confident93.1Very high41 Ų4143.6 Ų43.642%0.42325%0.246SC..THydrogen-bonded Turntrans86.75.8176.100000116.2
323G89.8Confident93.2Very high12 Ų1242.8 Ų42.812%0.12424%0.241CC..BIsolated β-bridgetrans65.5-148.5165.400000114.2C319 K325 M326C319-G323 PolarHBondContact N-O 2.94Å; C319-G323 WeakPolarHBondContact O-CA 3.49Å; C319-G323 PolarHBondContact O-N 3.36Å; G323-K325 VanDerWaalsContact C-N 3.35Å; G323-M326 PolarHBondContact O-N 3.03Å
324T88.1Confident93.4Very high5 Ų548 Ų483%0.03126%0.26CS..G310 helixtrans-66.4-33.6-178.744.60000113.2M326 C327 F412 T413T324-M326 PolarHBondContact O-N 3.22Å; T324-C327 PolarHBondContact O-N 2.99Å; T324-F412 WeakPolarHBondContact CG2-O 3.14Å; T324-F412 PolarHBondContact OG1-O 3.46Å; T324-T413 HydrophobicContact CG2-CG2 4.15Å
325K88.1Confident93.6Very high89 Ų8945.1 Ų45.139%0.38725%0.253SS..G310 helixtrans-58-33.9178.3-176.1168.5-174.7155.20113.5G323 Q328 D409G323-K325 VanDerWaalsContact C-N 3.35Å; K325-Q328 PolarHBondContact O-NE2 3.18Å; K325-D409 IonicContact NZ-OD1 2.74Å; K325-D409 PolarHBondContact NZ-OD1 3.42Å
326M93.6Very high94Very high57 Ų5743 Ų4328%0.28124%0.242SC..G310 helixtrans-85.6-13.8179.5-65.4-60.7160.700113.4C305 V306 N307 C319 G323 T324 Q328C305-M326 CarbonylContact C-O 3.59Å; C305-M326 WeakPolarHBondContact CA-O 3.46Å; V306-M326 HydrophobicContact CG2-CB 4.3Å; V306-M326 HydrophobicContact CG2-SD 3.56Å; V306-M326 VanDerWaalsContact CG2-SD 3.56Å; V306-M326 PolarHBondContact N-O 2.62Å; N307-M326 HydrophobicContact CB-SD 4.26Å; C319-M326 HydrophobicContact CB-CB 4.04Å; G323-M326 PolarHBondContact O-N 3.03Å; T324-M326 PolarHBondContact O-N 3.22Å; M326-Q328 PolarHBondContact O-N 3.47Å
327C95.6Very high94.3Very high0 Ų041.7 Ų41.70%023%0.233CC..EExtended strand (participates in β ladder)trans-85.9102.9174.9179.10000110C312 S317 T324C312-C327 HydrophobicContact CB-CB 4.03Å; C312-C327 WeakPolarHBondContact CB-SG 3.16Å; C312-C327 WeakPolarHBondContact SG-CA 3.45Å; C312-C327 WeakPolarHBondContact SG-CB 3.46Å; C312-C327 CovalentContact SG-SG 2.03Å; C312-C327 PolarHBondContact SG-SG 3.15Å; S317-C327 VanDerWaalsContact O-CB 3.23Å; S317-C327 WeakPolarHBondContact O-CB 3.44Å; T324-C327 PolarHBondContact O-N 2.99Å
328Q95.9Very high94.5Very high24 Ų2442.7 Ų42.711%0.11224%0.238CC..EExtended strand (participates in β ladder)trans-130.8143.3-176-56-171.1-2.700111.2Y252 P303 Y304 V306 K325 M326 F330 I404Y252-Q328 PolarHBondContact OH-NE2 3.39Å; P303-Q328 WeakPolarHBondContact CA-O 3.49Å; Y304-Q328 PolarHBondContact N-O 3.25Å; Y304-Q328 PolarHBondContact O-N 3.31Å; V306-Q328 HydrophobicContact CG1-CB 3.77Å; V306-Q328 HydrophobicContact CG1-CG 3.96Å; K325-Q328 PolarHBondContact O-NE2 3.18Å; M326-Q328 PolarHBondContact O-N 3.47Å; Q328-F330 HydrophobicContact CB-CE2 3.83Å; Q328-F330 HydrophobicContact CB-CZ 4.11Å; Q328-I404 WeakPolarHBondContact CA-O 3.07Å
329A97.1Very high94.7Very high7 Ų742 Ų426%0.05823%0.233CC..EExtended strand (participates in β ladder)trans-98.7144.6168.600000110.4N299 G302 P303 I404N299-A329 HydrophobicContact CB-CB 3.64Å; G302-A329 WeakPolarHBondContact O-CA 3.41Å; P303-A329 HydrophobicContact CB-CB 4.33Å; A329-I404 HydrophobicContact CB-CB 4.09Å; A329-I404 HydrophobicContact CB-CD1 3.81Å; A329-I404 HydrophobicContact CB-CG1 3.82Å; A329-I404 PolarHBondContact N-O 3.35Å
330F96.3Very high94.9Very high53 Ų5341.7 Ų41.723%0.23223%0.231CC..  trans-120.9149.3178-66.3-91.7000111.8N299 T300 R301 Y304 V306 Q328N299-F330 CarbonylContact C-O 3.5Å; N299-F330 WeakPolarHBondContact CA-O 3.14Å; T300-F330 PolarHBondContact N-O 2.79Å; R301-F330 VanDerWaalsContact CB-O 3.28Å; R301-F330 WeakPolarHBondContact CB-O 3.13Å; R301-F330 PolarHBondContact N-O 2.95Å; Y304-F330 HydrophobicContact CD1-CD2 4.44Å; Y304-F330 AromaticContact CE1-CD2 3.47Å; Y304-F330 HydrophobicContact CE1-CD2 3.47Å; Y304-F330 VanDerWaalsContact CE1-CD2 3.47Å; Y304-F330 AromaticContact CE1-CE2 3.96Å; Y304-F330 HydrophobicContact CE1-CE2 3.96Å; Y304-F330 HydrophobicContact CE1-CG 4.49Å; Y304-F330 HydrophobicContact CE2-CE2 4.22Å; Y304-F330 AromaticContact CZ-CD2 3.5Å; Y304-F330 AromaticContact CZ-CE2 3.58Å; Y304-F330 VanDerWaalsContact OH-CD2 3.23Å; Y304-F330 WeakPolarHBondContact OH-CD2 3.3Å; Y304-F330 WeakPolarHBondContact OH-CE2 3.44Å; V306-F330 HydrophobicContact CG1-CE2 3.59Å; V306-F330 HydrophobicContact CG1-CZ 3.75Å; Q328-F330 HydrophobicContact CB-CE2 3.83Å; Q328-F330 HydrophobicContact CB-CZ 4.11Å
331G97.3Very high95.3Very high3 Ų340.6 Ų40.63%0.03121%0.212CC..  trans-69.3174.3170.600000113.4N299 R301 G333 S339N299-G331 PolarHBondContact OD1-N 2.86Å; N299-G331 VanDerWaalsContact OD1-N 3.11Å; R301-G331 WeakPolarHBondContact CD-O 3.46Å; R301-G331 WeakPolarHBondContact CG-O 3.42Å; R301-G331 VanDerWaalsContact CZ-O 3.24Å; R301-G331 PolarHBondContact NE-O 2.81Å; R301-G331 VanDerWaalsContact NE-O 3.15Å; R301-G331 PolarHBondContact NH1-O 3.35Å; G331-G333 VanDerWaalsContact C-N 3.26Å; G331-G333 PolarHBondContact O-N 2.97Å; G331-S339 WeakPolarHBondContact CA-OG 3.3Å
332P97.9Very high95.7Very high39 Ų3938.1 Ų38.125%0.25320%0.195SC..SBendtrans-75.2-11.2-173.530.6-36.6000114.1R301 I342 I343R301-P332 PolarHBondContact NH2-O 3.33Å; P332-I342 HydrophobicContact CB-CG2 4.25Å; P332-I342 HydrophobicContact CG-CB 3.97Å; P332-I342 HydrophobicContact CG-CD1 4.32Å; P332-I342 HydrophobicContact CG-CG2 3.53Å; P332-I343 HydrophobicContact CG-CD1 3.91Å; P332-I343 HydrophobicContact CG-CG1 4.13Å
333G97.9Very high96.2Very high2 Ų236.2 Ų36.22%0.02118%0.175CC..SBendtrans-86.7173.2-174.400000114.8R301 G331 D335 D338 S339R301-G333 PolarHBondContact NH1-O 3.2Å; R301-G333 PolarHBondContact NH2-O 3.45Å; G331-G333 VanDerWaalsContact C-N 3.26Å; G331-G333 PolarHBondContact O-N 2.97Å; G333-D335 VanDerWaalsContact C-N 3.26Å; G333-D335 PolarHBondContact O-N 2.68Å; G333-D338 VanDerWaalsContact CA-OD2 3.31Å; G333-D338 WeakPolarHBondContact CA-OD2 3.31Å; G333-S339 WeakPolarHBondContact CA-OG 3.42Å; G333-S339 PolarHBondContact N-OG 3.47Å
334K97.1Very high96.7Very high176 Ų17635.6 Ų35.677%0.76517%0.169SC*.SBendtrans-68.3-27.7176.167.6-172.7179.2178.20113.2D338K334-D338 HydrophobicContact CG-CB 3.91Å; K334-D338 PolarHBondContact N-OD2 3.14Å
335D97.4Very high97.2Very high65 Ų6538.2 Ų38.235%0.34818%0.181SC..SBendtrans-145.5-176.1177.459.448.7000109.6G333 F337 D338 S339G333-D335 VanDerWaalsContact C-N 3.26Å; G333-D335 PolarHBondContact O-N 2.68Å; D335-F337 WeakPolarHBondContact OD1-CA 3.39Å; D335-F337 WeakPolarHBondContact OD1-CB 3.34Å; D335-F337 PolarHBondContact OD1-N 2.73Å; D335-D338 PolarHBondContact OD1-N 3.03Å; D335-S339 VanDerWaalsContact O-CB 3.29Å; D335-S339 WeakPolarHBondContact O-CB 3.34Å; D335-S339 PolarHBondContact O-N 2.88Å; D335-S339 PolarHBondContact O-OG 2.92Å
336M98.1Very high97.7Very high29 Ų2936.2 Ų36.214%0.14317%0.174CC..Hα-helixtrans-67.1-33.8179.460.517047.700113.4M250 N251 T253 N254 S339 T340M250-M336 HydrophobicContact CE-CG 4.31Å; M250-M336 HydrophobicContact CE-SD 3.74Å; M250-M336 HydrophobicContact SD-CB 4.11Å; M250-M336 HydrophobicContact SD-CG 3.89Å; M250-M336 HydrophobicContact SD-SD 3.94Å; N251-M336 HydrophobicContact CB-CE 4.04Å; N251-M336 WeakPolarHBondContact ND2-CE 3.32Å; N251-M336 WeakPolarHBondContact OD1-CE 3.46Å; T253-M336 WeakPolarHBondContact OG1-CE 3.45Å; N254-M336 HydrophobicContact CB-CE 4.18Å; N254-M336 HydrophobicContact CB-SD 3.83Å; M336-S339 PolarHBondContact O-N 3.14Å; M336-T340 WeakPolarHBondContact O-CB 3.46Å; M336-T340 PolarHBondContact O-N 2.84Å; M336-T340 PolarHBondContact O-OG1 2.91Å
337F98.5Very high97.9Very high29 Ų2933.5 Ų33.513%0.12716%0.161CC..Hα-helixtrans-69.7-46.6179.4-60.9-83.3000109.8H79 M250 M256 D335 S339 T340 R341 W659H79-F337 AromaticContact CE1-CD1 3.59Å; H79-F337 AromaticContact ND1-CD1 3.67Å; H79-F337 AromaticContact ND1-CE1 3.76Å; M250-F337 HydrophobicContact CE-CD1 3.67Å; M250-F337 HydrophobicContact CE-CE1 3.24Å; M250-F337 HydrophobicContact CE-CG 4.46Å; M250-F337 HydrophobicContact CE-CZ 3.72Å; M250-F337 HydrophobicContact SD-CD1 3.93Å; M250-F337 HydrophobicContact SD-CE1 4.13Å; M250-F337 HydrophobicContact SD-CG 4.38Å; M256-F337 HydrophobicContact CE-CE1 3.23Å; M256-F337 HydrophobicContact CE-CE2 4.42Å; M256-F337 HydrophobicContact CE-CZ 3.17Å; D335-F337 WeakPolarHBondContact OD1-CA 3.39Å; D335-F337 WeakPolarHBondContact OD1-CB 3.34Å; D335-F337 PolarHBondContact OD1-N 2.73Å; F337-S339 VanDerWaalsContact C-N 3.33Å; F337-S339 PolarHBondContact O-N 3.49Å; F337-T340 PolarHBondContact O-N 3.41Å; F337-R341 WeakPolarHBondContact O-CB 3.44Å; F337-R341 PolarHBondContact O-N 2.6Å; F337-W659 WeakPolarHBondContact O-CZ2 2.98Å
338D98.4Very high98.1Very high31 Ų3134.1 Ų34.117%0.16616%0.163CC..Hα-helixtrans-66.7-35.9177-169.943.4000111.6G333 K334 D335 R341 I342G333-D338 VanDerWaalsContact CA-OD2 3.31Å; G333-D338 WeakPolarHBondContact CA-OD2 3.31Å; K334-D338 HydrophobicContact CG-CB 3.91Å; K334-D338 PolarHBondContact N-OD2 3.14Å; D335-D338 PolarHBondContact OD1-N 3.03Å; D338-R341 WeakPolarHBondContact O-CB 3.45Å; D338-R341 PolarHBondContact O-N 2.86Å; D338-R341 IonicContact OD1-CZ 2.82Å; D338-R341 IonicContact OD1-NE 2.66Å; D338-R341 PolarHBondContact OD1-NE 3.42Å; D338-R341 IonicContact OD1-NH2 2.72Å; D338-R341 PolarHBondContact OD1-NH2 2.84Å; D338-I342 WeakPolarHBondContact O-CB 3.4Å; D338-I342 WeakPolarHBondContact O-CD1 3.46Å; D338-I342 WeakPolarHBondContact O-CG1 3.36Å; D338-I342 PolarHBondContact O-N 3.36Å
339S98.8Very high98.2Very high5 Ų536.8 Ų36.84%0.03518%0.178CC..Hα-helixtrans-62.3-46.8172.1-65.10000111.7G331 G333 D335 M336 F337 R341 I342 I343G331-S339 WeakPolarHBondContact CA-OG 3.3Å; G333-S339 WeakPolarHBondContact CA-OG 3.42Å; G333-S339 PolarHBondContact N-OG 3.47Å; D335-S339 VanDerWaalsContact O-CB 3.29Å; D335-S339 WeakPolarHBondContact O-CB 3.34Å; D335-S339 PolarHBondContact O-N 2.88Å; D335-S339 PolarHBondContact O-OG 2.92Å; M336-S339 PolarHBondContact O-N 3.14Å; F337-S339 VanDerWaalsContact C-N 3.33Å; F337-S339 PolarHBondContact O-N 3.49Å; S339-R341 VanDerWaalsContact C-N 3.31Å; S339-R341 PolarHBondContact O-N 3.11Å; S339-I342 PolarHBondContact O-N 2.93Å; S339-I343 VanDerWaalsContact O-CG1 3.29Å; S339-I343 WeakPolarHBondContact O-CG1 3.42Å; S339-I343 PolarHBondContact O-N 3.27Å
340T98.9Very high98.3Very high0 Ų038.4 Ų38.40%018%0.184CC..Hα-helixtrans-61.4-42.4176.6-53.70000111S249 M250 N261 M336 F337 G344 W659S249-T340 VanDerWaalsContact CB-CA 3.49Å; S249-T340 WeakPolarHBondContact CB-OG1 3.35Å; M250-T340 HydrophobicContact CG-CG2 4.26Å; M250-T340 WeakPolarHBondContact CG-OG1 3.36Å; M250-T340 PolarHBondContact N-OG1 3.42Å; M250-T340 PolarHBondContact SD-OG1 2.85Å; M250-T340 VanDerWaalsContact SD-OG1 3.4Å; N261-T340 HydrophobicContact CB-CG2 4.13Å; N261-T340 VanDerWaalsContact N-CG2 3.34Å; M336-T340 WeakPolarHBondContact O-CB 3.46Å; M336-T340 PolarHBondContact O-N 2.84Å; M336-T340 PolarHBondContact O-OG1 2.91Å; F337-T340 PolarHBondContact O-N 3.41Å; T340-G344 PolarHBondContact O-N 3.12Å; T340-W659 HydrophobicContact CG2-CH2 3.56Å; T340-W659 HydrophobicContact CG2-CZ3 4.33Å
341R98.6Very high98.4Very high94 Ų9435.9 Ų35.936%0.35517%0.173SC..Hα-helixtrans-59.5-51.9175.3-168.7-169.463.181.52.6111.5Y264 F337 D338 S339 H345 W659Y264-R341 HydrophobicContact CD1-CG 4.37Å; Y264-R341 WeakPolarHBondContact CD1-O 3.41Å; Y264-R341 HydrophobicContact CE1-CB 4.04Å; Y264-R341 HydrophobicContact CE1-CG 3.44Å; Y264-R341 VanDerWaalsContact CE1-CG 3.44Å; Y264-R341 VanDerWaalsContact CE1-O 3.3Å; Y264-R341 WeakPolarHBondContact CE1-O 3.4Å; Y264-R341 WeakPolarHBondContact OH-CG 3.5Å; F337-R341 WeakPolarHBondContact O-CB 3.44Å; F337-R341 PolarHBondContact O-N 2.6Å; D338-R341 WeakPolarHBondContact O-CB 3.45Å; D338-R341 PolarHBondContact O-N 2.86Å; D338-R341 IonicContact OD1-CZ 2.82Å; D338-R341 IonicContact OD1-NE 2.66Å; D338-R341 PolarHBondContact OD1-NE 3.42Å; D338-R341 IonicContact OD1-NH2 2.72Å; D338-R341 PolarHBondContact OD1-NH2 2.84Å; S339-R341 VanDerWaalsContact C-N 3.31Å; S339-R341 PolarHBondContact O-N 3.11Å; R341-H345 WeakPolarHBondContact O-CB 3.33Å; R341-H345 PolarHBondContact O-N 3.36Å; R341-W659 HydrophobicContact CB-CZ2 3.88Å
342I98.8Very high98.5Very high40 Ų4039.6 Ų39.621%0.20519%0.188CC..Hα-helixtrans-62.1-49.6-177.7-70.1162.6000110.7P332 D338 S339 H345 N346P332-I342 HydrophobicContact CB-CG2 4.25Å; P332-I342 HydrophobicContact CG-CB 3.97Å; P332-I342 HydrophobicContact CG-CD1 4.32Å; P332-I342 HydrophobicContact CG-CG2 3.53Å; D338-I342 WeakPolarHBondContact O-CB 3.4Å; D338-I342 WeakPolarHBondContact O-CD1 3.46Å; D338-I342 WeakPolarHBondContact O-CG1 3.36Å; D338-I342 PolarHBondContact O-N 3.36Å; S339-I342 PolarHBondContact O-N 2.93Å; I342-H345 PolarHBondContact O-N 3.02Å; I342-N346 VanDerWaalsContact O-CG 3.23Å; I342-N346 PolarHBondContact O-N 3.48Å; I342-N346 PolarHBondContact O-OD1 3.29Å
343I98.9Very high98.5Very high0 Ų042 Ų420%020%0.196CC..Hα-helixtrans-64.2-48.5-178.9-62.2-67.4000110.5N261 P298 T300 P332 S339 H345 N346 I347N261-I343 HydrophobicContact CB-CB 4.15Å; N261-I343 HydrophobicContact CB-CG2 3.86Å; P298-I343 HydrophobicContact CB-CG1 4.21Å; P298-I343 HydrophobicContact CB-CG2 3.94Å; P298-I343 WeakPolarHBondContact O-CD1 3.35Å; T300-I343 HydrophobicContact CG2-CD1 4.24Å; P332-I343 HydrophobicContact CG-CD1 3.91Å; P332-I343 HydrophobicContact CG-CG1 4.13Å; S339-I343 VanDerWaalsContact O-CG1 3.29Å; S339-I343 WeakPolarHBondContact O-CG1 3.42Å; S339-I343 PolarHBondContact O-N 3.27Å; I343-H345 VanDerWaalsContact C-N 3.33Å; I343-H345 PolarHBondContact O-N 3.39Å; I343-N346 PolarHBondContact O-N 2.88Å; I343-I347 HydrophobicContact CG2-CD1 3.88Å; I343-I347 VanDerWaalsContact O-CG1 3.29Å; I343-I347 WeakPolarHBondContact O-CG1 3.37Å; I343-I347 PolarHBondContact O-N 3.47Å; I343-I347 VanDerWaalsContact O-N 3.11Å
344G98.8Very high98.5Very high0 Ų042.3 Ų42.30%020%0.197CC..Hα-helixtrans-62.6-38.2177.800000112.9N261 A265 T340 I347 Y348N261-G344 WeakPolarHBondContact O-CA 3.16Å; A265-G344 WeakPolarHBondContact CB-O 3.4Å; T340-G344 PolarHBondContact O-N 3.12Å; G344-I347 PolarHBondContact O-N 2.95Å; G344-Y348 WeakPolarHBondContact O-CB 3.48Å; G344-Y348 PolarHBondContact O-N 3Å
345H98.8Very high98.6Very high60 Ų6034.3 Ų34.328%0.27816%0.162SC..Hα-helixtrans-65-42.2176.6-167.489.8000112.1Y264 L268 R341 I342 I343 I347 Y348 L349Y264-H345 HydrophobicContact CE1-CB 4.3Å; L268-H345 HydrophobicContact CD1-CB 4.12Å; L268-H345 WeakPolarHBondContact CD1-ND1 3.34Å; R341-H345 WeakPolarHBondContact O-CB 3.33Å; R341-H345 PolarHBondContact O-N 3.36Å; I342-H345 PolarHBondContact O-N 3.02Å; I343-H345 VanDerWaalsContact C-N 3.33Å; I343-H345 PolarHBondContact O-N 3.39Å; H345-I347 VanDerWaalsContact C-N 3.33Å; H345-I347 PolarHBondContact O-N 3.11Å; H345-Y348 WeakPolarHBondContact O-CD1 3.4Å; H345-Y348 PolarHBondContact O-N 2.79Å; H345-L349 VanDerWaalsContact CD2-CD1 3.46Å; H345-L349 WeakPolarHBondContact CD2-CD1 3.33Å; H345-L349 WeakPolarHBondContact O-CG 3.42Å; H345-L349 PolarHBondContact O-N 2.76Å
346N98.8Very high98.5Very high47 Ų4734.5 Ų34.525%0.25117%0.173SC..Hα-helixtrans-61.3-43.4175.8-70.4-9.6000111.7L193 S196 I342 I343 L349 K350L193-N346 HydrophobicContact CD1-CB 4.29Å; S196-N346 WeakPolarHBondContact OG-CB 3.44Å; S196-N346 PolarHBondContact OG-ND2 3.36Å; I342-N346 VanDerWaalsContact O-CG 3.23Å; I342-N346 PolarHBondContact O-N 3.48Å; I342-N346 PolarHBondContact O-OD1 3.29Å; I343-N346 PolarHBondContact O-N 2.88Å; N346-L349 PolarHBondContact O-N 2.77Å; N346-K350 PolarHBondContact O-N 2.82Å; N346-K350 VanDerWaalsContact O-N 3.11Å
347I98.8Very high98.5Very high0 Ų037.8 Ų37.80%019%0.191CC..Hα-helixtrans-61.7-46.1176-65.6165.4000110.5L193 F243 V245 M262 A265 F288 I343 G344 H345 A351L193-I347 HydrophobicContact CD2-CB 4.29Å; L193-I347 HydrophobicContact CD2-CG1 3.72Å; F243-I347 HydrophobicContact CD1-CD1 3.98Å; F243-I347 HydrophobicContact CD1-CG1 3.89Å; F243-I347 HydrophobicContact CE1-CD1 4.23Å; F243-I347 HydrophobicContact CE1-CG1 4.06Å; V245-I347 HydrophobicContact CG1-CD1 3.97Å; M262-I347 HydrophobicContact SD-CD1 3.98Å; A265-I347 HydrophobicContact CB-CB 4.06Å; A265-I347 HydrophobicContact CB-CG2 3.8Å; F288-I347 HydrophobicContact CD1-CG2 3.55Å; F288-I347 HydrophobicContact CE1-CG2 3.55Å; I343-I347 HydrophobicContact CG2-CD1 3.88Å; I343-I347 VanDerWaalsContact O-CG1 3.29Å; I343-I347 WeakPolarHBondContact O-CG1 3.37Å; I343-I347 PolarHBondContact O-N 3.47Å; I343-I347 VanDerWaalsContact O-N 3.11Å; G344-I347 PolarHBondContact O-N 2.95Å; H345-I347 VanDerWaalsContact C-N 3.33Å; H345-I347 PolarHBondContact O-N 3.11Å; I347-A351 WeakPolarHBondContact O-CB 3.3Å; I347-A351 PolarHBondContact O-N 2.89Å
348Y98.8Very high98.4Very high12 Ų1236.7 Ų36.75%0.04719%0.187CC..Hα-helixtrans-60-48.3175.8148.1-95.2000112.1L268 L269 D272 G344 H345 K350 A351 K352L268-Y348 HydrophobicContact CB-CD1 4.06Å; L268-Y348 HydrophobicContact CB-CD2 3.53Å; L268-Y348 HydrophobicContact CB-CE1 4.4Å; L268-Y348 HydrophobicContact CB-CE2 3.89Å; L268-Y348 HydrophobicContact CB-CG 3.63Å; L268-Y348 HydrophobicContact CD1-CD1 3.7Å; L268-Y348 HydrophobicContact CD1-CE1 4.31Å; L268-Y348 HydrophobicContact CD1-CG 3.88Å; L268-Y348 HydrophobicContact CG-CG 4.44Å; L269-Y348 HydrophobicContact CB-CD2 3.95Å; L269-Y348 HydrophobicContact CB-CE2 4.3Å; L269-Y348 HydrophobicContact CD1-CD2 4.32Å; L269-Y348 HydrophobicContact CD1-CE2 4.08Å; D272-Y348 PolarHBondContact OD1-OH 3.25Å; D272-Y348 WeakPolarHBondContact OD2-CE2 3.35Å; D272-Y348 VanDerWaalsContact OD2-CZ 3.28Å; D272-Y348 PolarHBondContact OD2-OH 3.26Å; G344-Y348 WeakPolarHBondContact O-CB 3.48Å; G344-Y348 PolarHBondContact O-N 3Å; H345-Y348 WeakPolarHBondContact O-CD1 3.4Å; H345-Y348 PolarHBondContact O-N 2.79Å; Y348-K350 VanDerWaalsContact C-N 3.34Å; Y348-K350 PolarHBondContact O-N 3.38Å; Y348-A351 PolarHBondContact O-N 3.05Å; Y348-K352 HydrophobicContact CE1-CD 4.48Å; Y348-K352 HydrophobicContact CE2-CB 4.29Å; Y348-K352 HydrophobicContact CE2-CD 3.83Å; Y348-K352 VanDerWaalsContact O-CB 3.29Å; Y348-K352 WeakPolarHBondContact O-CB 3.49Å; Y348-K352 PolarHBondContact O-N 3.32Å; Y348-K352 VanDerWaalsContact OH-CD 3.23Å; Y348-K352 WeakPolarHBondContact OH-CD 3.3Å; Y348-K352 PolarHBondContact OH-NZ 3.08Å
349L98.8Very high98.2Very high81 Ų8141.2 Ų41.242%0.42422%0.216SC..Hα-helixtrans-60-45.6-178.6-77.7178.5000111.2H345 N346 K352 E353H345-L349 VanDerWaalsContact CD2-CD1 3.46Å; H345-L349 WeakPolarHBondContact CD2-CD1 3.33Å; H345-L349 WeakPolarHBondContact O-CG 3.42Å; H345-L349 PolarHBondContact O-N 2.76Å; N346-L349 PolarHBondContact O-N 2.77Å; L349-K352 PolarHBondContact O-N 3.41Å; L349-E353 WeakPolarHBondContact O-CB 3.43Å; L349-E353 PolarHBondContact O-N 2.91Å
350K98.8Very high98Very high41 Ų4145.6 Ų45.618%0.17824%0.236CC..Hα-helixtrans-63.4-45.3176.6-177.957.257.2-175.70111.4E192 L193 V224 N346 Y348 K352 E353 L354E192-K350 WeakPolarHBondContact O-CE 3.39Å; L193-K350 HydrophobicContact CB-CB 4.46Å; L193-K350 HydrophobicContact CB-CG 4.19Å; L193-K350 HydrophobicContact CD1-CB 4.2Å; L193-K350 HydrophobicContact CD2-CB 4.43Å; V224-K350 HydrophobicContact CB-CG 4.06Å; V224-K350 HydrophobicContact CG1-CG 4.4Å; V224-K350 HydrophobicContact CG2-CG 3.89Å; N346-K350 PolarHBondContact O-N 2.82Å; N346-K350 VanDerWaalsContact O-N 3.11Å; Y348-K350 VanDerWaalsContact C-N 3.34Å; Y348-K350 PolarHBondContact O-N 3.38Å; K350-K352 PolarHBondContact O-N 3.09Å; K350-E353 WeakPolarHBondContact CE-OE2 3.42Å; K350-E353 IonicContact NZ-OE1 3.52Å; K350-E353 IonicContact NZ-OE2 3.33Å; K350-E353 PolarHBondContact NZ-OE2 3.02Å; K350-E353 WeakPolarHBondContact O-CB 3.37Å; K350-E353 PolarHBondContact O-N 3.03Å; K350-L354 HydrophobicContact CD-CD1 4.15Å; K350-L354 HydrophobicContact CD-CG 4.13Å; K350-L354 HydrophobicContact CG-CD1 4.07Å; K350-L354 HydrophobicContact CG-CG 4.45Å; K350-L354 WeakPolarHBondContact O-CB 3.48Å; K350-L354 VanDerWaalsContact O-CG 3.27Å; K350-L354 WeakPolarHBondContact O-CG 3.28Å; K350-L354 PolarHBondContact O-N 2.83Å
351A98.6Very high97.9Very high0 Ų048 Ų480%025%0.247CC..Hα-helixtrans-64.7-40179.100000112.2V226 M239 F288 I347 Y348 L354 Y355V226-A351 HydrophobicContact CG2-CB 4.13Å; M239-A351 HydrophobicContact CE-CB 3.91Å; M239-A351 HydrophobicContact SD-CB 4.22Å; F288-A351 HydrophobicContact CE1-CB 3.48Å; F288-A351 VanDerWaalsContact CE1-CB 3.48Å; F288-A351 HydrophobicContact CZ-CB 3.62Å; I347-A351 WeakPolarHBondContact O-CB 3.3Å; I347-A351 PolarHBondContact O-N 2.89Å; Y348-A351 PolarHBondContact O-N 3.05Å; A351-L354 PolarHBondContact O-N 2.85Å; A351-Y355 WeakPolarHBondContact O-CB 3.27Å; A351-Y355 PolarHBondContact O-N 3.16Å
352K98.4Very high97.7Very high81 Ų8143.6 Ų43.635%0.35223%0.23SC..Hα-helixtrans-62.5-44.1175.1178173.1173.9174.20112L269 D272 Y348 L349 K350 Y355 A356L269-K352 HydrophobicContact CD1-CB 4.3Å; D272-K352 WeakPolarHBondContact OD2-CD 3.49Å; D272-K352 WeakPolarHBondContact OD2-CE 3.47Å; D272-K352 IonicContact OD2-NZ 3.33Å; D272-K352 PolarHBondContact OD2-NZ 2.75Å; Y348-K352 HydrophobicContact CE1-CD 4.48Å; Y348-K352 HydrophobicContact CE2-CB 4.29Å; Y348-K352 HydrophobicContact CE2-CD 3.83Å; Y348-K352 VanDerWaalsContact O-CB 3.29Å; Y348-K352 WeakPolarHBondContact O-CB 3.49Å; Y348-K352 PolarHBondContact O-N 3.32Å; Y348-K352 VanDerWaalsContact OH-CD 3.23Å; Y348-K352 WeakPolarHBondContact OH-CD 3.3Å; Y348-K352 PolarHBondContact OH-NZ 3.08Å; L349-K352 PolarHBondContact O-N 3.41Å; K350-K352 PolarHBondContact O-N 3.09Å; K352-Y355 PolarHBondContact O-N 3.47Å; K352-A356 WeakPolarHBondContact O-CB 3.41Å; K352-A356 PolarHBondContact O-N 3.44Å
353E98.5Very high97.5Very high90 Ų9045 Ų4542%0.42124%0.241SC..Hα-helixtrans-57.5-51.5173.1-179.7-160153.800111L349 K350 Y355 A356 N357L349-E353 WeakPolarHBondContact O-CB 3.43Å; L349-E353 PolarHBondContact O-N 2.91Å; K350-E353 WeakPolarHBondContact CE-OE2 3.42Å; K350-E353 IonicContact NZ-OE1 3.52Å; K350-E353 IonicContact NZ-OE2 3.33Å; K350-E353 PolarHBondContact NZ-OE2 3.02Å; K350-E353 WeakPolarHBondContact O-CB 3.37Å; K350-E353 PolarHBondContact O-N 3.03Å; E353-Y355 PolarHBondContact O-N 3.06Å; E353-A356 PolarHBondContact O-N 2.97Å; E353-N357 WeakPolarHBondContact O-CB 2.98Å; E353-N357 PolarHBondContact O-N 3.46Å; E353-N357 VanDerWaalsContact O-N 3.13Å; E353-N357 PolarHBondContact O-ND2 3.07Å; E353-N357 VanDerWaalsContact O-ND2 3.11Å
354L98.6Very high97.3Very high7 Ų746.9 Ų46.94%0.03726%0.26CS..Hα-helixtrans-64.1-40.4-179.5-70177.1000112.2N189 R190 V224 V226 K350 A351 N357 A358N189-L354 HydrophobicContact CB-CB 4.18Å; N189-L354 HydrophobicContact CB-CD2 4.33Å; N189-L354 WeakPolarHBondContact CB-O 3.4Å; N189-L354 PolarHBondContact ND2-O 3.38Å; R190-L354 VanDerWaalsContact C-CD2 3.43Å; R190-L354 WeakPolarHBondContact O-CD2 3.2Å; V224-L354 HydrophobicContact CB-CD1 3.91Å; V224-L354 HydrophobicContact CG1-CD1 3.86Å; V224-L354 WeakPolarHBondContact O-CD1 3.45Å; V226-L354 HydrophobicContact CB-CB 4.14Å; V226-L354 HydrophobicContact CG2-CB 3.86Å; V226-L354 HydrophobicContact CG2-CD1 4.18Å; K350-L354 HydrophobicContact CD-CD1 4.15Å; K350-L354 HydrophobicContact CD-CG 4.13Å; K350-L354 HydrophobicContact CG-CD1 4.07Å; K350-L354 HydrophobicContact CG-CG 4.45Å; K350-L354 WeakPolarHBondContact O-CB 3.48Å; K350-L354 VanDerWaalsContact O-CG 3.27Å; K350-L354 WeakPolarHBondContact O-CG 3.28Å; K350-L354 PolarHBondContact O-N 2.83Å; A351-L354 PolarHBondContact O-N 2.85Å; L354-N357 CarbonylContact O-C 3.51Å; L354-N357 PolarHBondContact O-N 3Å; L354-A358 WeakPolarHBondContact O-CB 3.05Å; L354-A358 PolarHBondContact O-N 3.15Å
355Y97.9Very high97.1Very high8 Ų848.1 Ų48.13%0.03127%0.268CS..Hα-helixtrans-60.3-47.5175.7-179.6-86.4000112V226 K228 G236 M239 F284 A351 K352 E353 N357 A358V226-Y355 HydrophobicContact CG1-CD2 4.39Å; K228-Y355 HydrophobicContact CB-CD2 3.72Å; K228-Y355 HydrophobicContact CB-CE2 3.61Å; K228-Y355 HydrophobicContact CD-CD1 4.37Å; K228-Y355 HydrophobicContact CD-CD2 4.13Å; K228-Y355 HydrophobicContact CD-CE1 4.01Å; K228-Y355 HydrophobicContact CD-CE2 3.8Å; K228-Y355 HydrophobicContact CD-CG 4.39Å; K228-Y355 WeakPolarHBondContact CD-O 3.48Å; K228-Y355 HydrophobicContact CG-CD2 3.96Å; K228-Y355 HydrophobicContact CG-CE1 4.48Å; K228-Y355 HydrophobicContact CG-CE2 3.41Å; K228-Y355 VanDerWaalsContact CG-CE2 3.41Å; G236-Y355 WeakPolarHBondContact CA-OH 3.47Å; M239-Y355 HydrophobicContact CB-CD2 3.87Å; M239-Y355 HydrophobicContact CB-CE2 3.98Å; M239-Y355 HydrophobicContact CG-CD2 3.71Å; M239-Y355 HydrophobicContact CG-CE2 4.29Å; M239-Y355 HydrophobicContact SD-CD2 3.78Å; M239-Y355 HydrophobicContact SD-CG 4.26Å; F284-Y355 HydrophobicContact CE2-CE2 4.29Å; F284-Y355 HydrophobicContact CZ-CE2 4.06Å; A351-Y355 WeakPolarHBondContact O-CB 3.27Å; A351-Y355 PolarHBondContact O-N 3.16Å; K352-Y355 PolarHBondContact O-N 3.47Å; E353-Y355 PolarHBondContact O-N 3.06Å; Y355-N357 VanDerWaalsContact C-N 3.28Å; Y355-N357 PolarHBondContact O-N 3.12Å; Y355-A358 PolarHBondContact O-N 2.87Å
356A96.6Very high97Very high70 Ų7045.3 Ų45.358%0.57926%0.255SS*.Hα-helixtrans-63.3-36.6179.700000111.9K352 E353K352-A356 WeakPolarHBondContact O-CB 3.41Å; K352-A356 PolarHBondContact O-N 3.44Å; E353-A356 PolarHBondContact O-N 2.97Å
357N97.2Very high97Very high97 Ų9745.2 Ų45.252%0.51925%0.251SS..THydrogen-bonded Turntrans-95.46.2-176.3-64.1-40000114.3N189 E353 L354 Y355 V359N189-N357 PolarHBondContact ND2-O 3.44Å; E353-N357 WeakPolarHBondContact O-CB 2.98Å; E353-N357 PolarHBondContact O-N 3.46Å; E353-N357 VanDerWaalsContact O-N 3.13Å; E353-N357 PolarHBondContact O-ND2 3.07Å; E353-N357 VanDerWaalsContact O-ND2 3.11Å; L354-N357 CarbonylContact O-C 3.51Å; L354-N357 PolarHBondContact O-N 3Å; Y355-N357 VanDerWaalsContact C-N 3.28Å; Y355-N357 PolarHBondContact O-N 3.12Å; N357-V359 PolarHBondContact O-N 2.76Å; N357-V359 VanDerWaalsContact O-N 3.15Å
358A96.3Very high97Very high7 Ų746.2 Ų46.26%0.05826%0.255CS..  trans-72.5107.3-178.600000111N189 K228 L354 Y355N189-A358 HydrophobicContact CB-CB 3.88Å; K228-A358 HydrophobicContact CB-CB 4.2Å; K228-A358 HydrophobicContact CD-CB 4.24Å; L354-A358 WeakPolarHBondContact O-CB 3.05Å; L354-A358 PolarHBondContact O-N 3.15Å; Y355-A358 PolarHBondContact O-N 2.87Å
359V94.4Very high97Very high126 Ų12645.6 Ų45.676%0.76425%0.253SS*.  trans-118.8-14.9-179.5-630000113.6N357 E361N357-V359 PolarHBondContact O-N 2.76Å; N357-V359 VanDerWaalsContact O-N 3.15Å; V359-E361 PolarHBondContact O-N 3.05Å
360E95.5Very high97Very high96 Ų9642.4 Ų42.445%0.44924%0.236SC..EExtended strand (participates in β ladder)trans-79.9104.8179.1-169.4-174.4-176.200109.9Y187 R188Y187-E360 CarbonylContact C-O 3.51Å; Y187-E360 VanDerWaalsContact CA-O 3.29Å; Y187-E360 WeakPolarHBondContact CA-O 3.45Å; R188-E360 HydrophobicContact CG-CB 4.14Å; R188-E360 HydrophobicContact CG-CG 4.26Å; R188-E360 WeakPolarHBondContact CG-OE2 3.48Å; R188-E360 IonicContact CZ-OE1 3.67Å; R188-E360 VanDerWaalsContact CZ-OE1 3.3Å; R188-E360 IonicContact CZ-OE2 3.36Å; R188-E360 PolarHBondContact N-O 3.09Å; R188-E360 IonicContact NE-OE1 2.65Å; R188-E360 PolarHBondContact NE-OE1 3.25Å; R188-E360 IonicContact NE-OE2 3.36Å; R188-E360 PolarHBondContact NE-OE2 2.93Å; R188-E360 IonicContact NH2-OE1 3.44Å; R188-E360 PolarHBondContact NH2-OE1 2.85Å; R188-E360 IonicContact NH2-OE2 2.85Å
361E95.6Very high96.9Very high52 Ų5240.8 Ų40.824%0.24323%0.229CC..EExtended strand (participates in β ladder)trans-70.4131.5179.5-165.5177.8175.100111.7R185 I186 Y187 V359 T363R185-E361 VanDerWaalsContact CD-OE1 3.3Å; R185-E361 WeakPolarHBondContact CD-OE1 3.24Å; R185-E361 IonicContact CZ-OE1 3.64Å; R185-E361 IonicContact NE-OE1 3.68Å; R185-E361 IonicContact NH1-OE1 2.92Å; R185-E361 PolarHBondContact NH1-OE1 2.71Å; R185-E361 IonicContact NH1-OE2 3.37Å; I186-E361 CarbonylContact O-C 3.48Å; I186-E361 WeakPolarHBondContact O-CA 3.47Å; Y187-E361 HydrophobicContact CD1-CB 3.96Å; Y187-E361 HydrophobicContact CD1-CG 4.37Å; Y187-E361 HydrophobicContact CE1-CB 3.79Å; Y187-E361 HydrophobicContact CE1-CG 4.02Å; V359-E361 PolarHBondContact O-N 3.05Å; E361-T363 HydrophobicContact CB-CG2 4.46Å; E361-T363 HydrophobicContact CG-CG2 3.92Å; E361-T363 PolarHBondContact O-N 3.41Å
362V95.9Very high96.9Very high0 Ų042 Ų420%023%0.234CC..  trans-86.1106.4174.41800000108.5Y47 I186 R188 L227 V472 V475Y47-V362 VanDerWaalsContact CE2-O 3.23Å; Y47-V362 WeakPolarHBondContact CE2-O 3.28Å; Y47-V362 PolarHBondContact OH-O 2.9Å; I186-V362 HydrophobicContact CB-CB 4.12Å; I186-V362 HydrophobicContact CG2-CB 4Å; I186-V362 HydrophobicContact CG2-CG2 4.07Å; I186-V362 PolarHBondContact O-N 2.78Å; R188-V362 HydrophobicContact CB-CG2 3.75Å; R188-V362 HydrophobicContact CG-CG2 3.9Å; L227-V362 HydrophobicContact CD2-CG2 4.22Å; V362-V472 HydrophobicContact CG1-CG1 4.37Å; V362-V472 WeakPolarHBondContact CG1-O 3.39Å; V362-V475 HydrophobicContact CG1-CB 4.45Å; V362-V475 HydrophobicContact CG1-CG2 3.89Å; V362-V475 HydrophobicContact CG2-CG2 3.82Å
363T94.5Very high97Very high71 Ų7138.7 Ų38.744%0.43622%0.22SC..  trans-119.5158.6179.157.50000111.2Y47 E361 G473 S474Y47-T363 WeakPolarHBondContact OH-CA 3.36Å; E361-T363 HydrophobicContact CB-CG2 4.46Å; E361-T363 HydrophobicContact CG-CG2 3.92Å; E361-T363 PolarHBondContact O-N 3.41Å; T363-G473 CarbonylContact O-C 3.58Å; T363-G473 WeakPolarHBondContact O-CA 3.43Å; T363-S474 PolarHBondContact O-N 2.89Å
364G93.3Very high97Very high38 Ų3837.1 Ų37.139%0.39222%0.215SC..SBendtrans120.9-177.4177.500000112.9Y47Y47-G364 WeakPolarHBondContact CE1-O 3.28Å; Y47-G364 PolarHBondContact OH-N 3.07Å; Y47-G364 PolarHBondContact OH-O 2.88Å; Y47-G364 VanDerWaalsContact OH-O 3.07Å
365P95.1Very high97Very high27 Ų2736.8 Ų36.818%0.17521%0.213CC..  trans-70.3151.3-175.724.8-31.3000113.5R367 G473 T505 F506P365-R367 HydrophobicContact CB-CG 4.45Å; P365-G473 PolarHBondContact O-N 2.69Å; P365-T505 HydrophobicContact CG-CG2 4Å; P365-F506 HydrophobicContact CG-CZ 4.29Å
366V97.4Very high97Very high0 Ų037.5 Ų37.50%022%0.218CC..EExtended strand (participates in β ladder)trans-80.6130.5159.5171.40000108.7Y47 I89 D91 R94 V96 T471Y47-V366 HydrophobicContact CD1-CG2 4.43Å; Y47-V366 HydrophobicContact CE1-CG2 4.29Å; I89-V366 HydrophobicContact CG2-CG2 4.1Å; D91-V366 HydrophobicContact CB-CB 4.16Å; D91-V366 HydrophobicContact CB-CG2 3.93Å; D91-V366 PolarHBondContact OD2-N 3.42Å; R94-V366 HydrophobicContact CB-CB 4.3Å; R94-V366 HydrophobicContact CB-CG1 4.12Å; R94-V366 WeakPolarHBondContact CD-O 3.07Å; V96-V366 HydrophobicContact CB-CG1 4.19Å; V96-V366 HydrophobicContact CG1-CG1 3.49Å; V96-V366 VanDerWaalsContact CG1-CG1 3.49Å; V96-V366 HydrophobicContact CG2-CG1 3.79Å; V366-T471 VanDerWaalsContact CA-O 3.28Å; V366-T471 WeakPolarHBondContact CA-O 3.37Å
367R97.7Very high96.8Very high45 Ų4537.3 Ų37.317%0.1722%0.216CC..EExtended strand (participates in β ladder)trans-137.2161.8172.9-57.2-70.7-177-100.35.5109.9R94 P365 I470 T471 F506 I561 D564R94-R367 VanDerWaalsContact CZ-CD 3.49Å; P365-R367 HydrophobicContact CB-CG 4.45Å; R367-I470 CarbonylContact O-C 3.58Å; R367-I470 WeakPolarHBondContact O-CA 3.44Å; R367-T471 VanDerWaalsContact CB-OG1 3.27Å; R367-T471 WeakPolarHBondContact CB-OG1 3.42Å; R367-T471 PolarHBondContact N-O 3.39Å; R367-T471 PolarHBondContact N-OG1 3.31Å; R367-T471 PolarHBondContact O-N 3.35Å; R367-F506 HydrophobicContact CG-CZ 4.04Å; R367-I561 HydrophobicContact CB-CG2 3.78Å; R367-I561 HydrophobicContact CG-CG2 4.19Å; R367-D564 IonicContact NE-OD1 3.19Å; R367-D564 PolarHBondContact NE-OD1 3.09Å
368F98.3Very high96.9Very high21 Ų2133.2 Ų33.29%0.09220%0.195CC..EExtended strand (participates in β ladder)trans-154.4152.8174.250.2-102.5000109.7R94 V96 D129 N130 I469 I470 V566R94-F368 HydrophobicContact CB-CE1 4.11Å; R94-F368 HydrophobicContact CG-CE1 4.47Å; V96-F368 HydrophobicContact CG1-CB 4.2Å; V96-F368 HydrophobicContact CG1-CD1 3.64Å; V96-F368 HydrophobicContact CG1-CG 4.36Å; D129-F368 HydrophobicContact CB-CD2 3.88Å; D129-F368 HydrophobicContact CB-CE2 4.16Å; D129-F368 WeakPolarHBondContact O-CB 3.29Å; D129-F368 WeakPolarHBondContact OD2-CE2 3.34Å; N130-F368 HydrophobicContact CB-CD1 3.7Å; N130-F368 HydrophobicContact CB-CD2 4.33Å; N130-F368 HydrophobicContact CB-CE1 3.78Å; N130-F368 HydrophobicContact CB-CE2 4.47Å; N130-F368 HydrophobicContact CB-CG 3.98Å; N130-F368 HydrophobicContact CB-CZ 4.19Å; F368-I469 CarbonylContact C-O 3.5Å; F368-I469 VanDerWaalsContact CA-O 3.24Å; F368-I469 WeakPolarHBondContact CA-O 3.46Å; F368-I470 HydrophobicContact CB-CG2 3.92Å; F368-V566 WeakPolarHBondContact O-CG1 3.35Å
369A98.6Very high96.9Very high0 Ų037.1 Ų37.10%022%0.218CC..EExtended strand (participates in β ladder)trans-145.6142169.800000109Q468 I469 L557 I561 V566 L569A369-Q468 VanDerWaalsContact O-CA 3.31Å; A369-Q468 WeakPolarHBondContact O-CA 3.26Å; A369-I469 PolarHBondContact N-O 2.84Å; A369-I469 PolarHBondContact O-N 3.38Å; A369-L557 HydrophobicContact CB-CB 4.21Å; A369-L557 HydrophobicContact CB-CD2 4.35Å; A369-L557 HydrophobicContact CB-CG 4.11Å; A369-I561 HydrophobicContact CB-CD1 3.78Å; A369-I561 HydrophobicContact CB-CG1 3.73Å; A369-V566 HydrophobicContact CB-CG1 3.8Å; A369-V566 HydrophobicContact CB-CG2 4.01Å; A369-L569 HydrophobicContact CB-CD1 4.14Å
370H98.8Very high96.9Very high13 Ų1331.7 Ų31.76%0.0619%0.185CC..EExtended strand (participates in β ladder)trans-141.4148.1178.5167.3-78.3000109.4H128 D129 W372 D466 V467 Q468H128-H370 AromaticContact CD2-CE1 3.72Å; H128-H370 AromaticContact CD2-CG 3.87Å; H128-H370 AromaticContact CD2-ND1 3.32Å; H128-H370 PolarHBondContact CD2-ND1 3.01Å; H128-H370 VanDerWaalsContact CD2-ND1 3.32Å; D129-H370 HydrophobicContact CB-CB 3.97Å; H370-W372 AromaticContact CE1-CD1 3.65Å; H370-W372 AromaticContact CE1-CD2 3.71Å; H370-W372 AromaticContact CE1-CE2 3.54Å; H370-W372 AromaticContact CE1-CG 3.79Å; H370-W372 AromaticContact CE1-NE1 3.47Å; H370-W372 PolarHBondContact CE1-NE1 3.07Å; H370-W372 AromaticContact NE2-CD1 3.86Å; H370-W372 AromaticContact NE2-NE1 3.62Å; H370-D466 IonicContact CD2-OD1 2.77Å; H370-D466 IonicContact CE1-OD1 3.91Å; H370-D466 IonicContact NE2-OD1 2.76Å; H370-D466 PolarHBondContact NE2-OD1 3.18Å; H370-V467 VanDerWaalsContact CA-O 3.31Å; H370-V467 WeakPolarHBondContact CA-O 3.35Å; H370-Q468 HydrophobicContact CB-CB 4.36Å; H370-Q468 HydrophobicContact CB-CG 4.21Å
371Q98.6Very high96.9Very high7 Ų733 Ų333%0.03319%0.19CC..EExtended strand (participates in β ladder)trans-141.9147.6164.1-61.1-175.1-61.300109.7V373 V467 L557 P570Q371-V373 HydrophobicContact CB-CG2 4.22Å; Q371-V467 HydrophobicContact CB-CG2 3.92Å; Q371-V467 PolarHBondContact N-O 3.36Å; Q371-V467 PolarHBondContact O-N 2.75Å; Q371-L557 HydrophobicContact CG-CD1 4.16Å; Q371-P570 WeakPolarHBondContact CG-O 3.44Å; Q371-P570 VanDerWaalsContact NE2-CD 3.27Å; Q371-P570 PolarHBondContact NE2-O 3.5Å
372W98.8Very high96.6Very high26 Ų2634.8 Ų34.810%0.09820%0.2CC..EExtended strand (participates in β ladder)trans-86131.6157.1-67.6-57.2000109.8H128 H370 I464 D466 V571 G572 P573 E574H128-W372 HydrophobicContact CB-CZ2 4.1Å; H128-W372 AromaticContact ND1-CH2 3.99Å; H370-W372 AromaticContact CE1-CD1 3.65Å; H370-W372 AromaticContact CE1-CD2 3.71Å; H370-W372 AromaticContact CE1-CE2 3.54Å; H370-W372 AromaticContact CE1-CG 3.79Å; H370-W372 AromaticContact CE1-NE1 3.47Å; H370-W372 PolarHBondContact CE1-NE1 3.07Å; H370-W372 AromaticContact NE2-CD1 3.86Å; H370-W372 AromaticContact NE2-NE1 3.62Å; W372-I464 HydrophobicContact CB-CG2 3.77Å; W372-I464 HydrophobicContact CG-CG2 4.2Å; W372-D466 PolarHBondContact NE1-OD1 2.9Å; W372-D466 VanDerWaalsContact NE1-OD1 3.14Å; W372-V571 HydrophobicContact CE3-CG1 3.84Å; W372-V571 HydrophobicContact CZ3-CG1 3.78Å; W372-V571 PolarHBondContact N-O 3.24Å; W372-G572 WeakPolarHBondContact O-CA 3.33Å; W372-P573 WeakPolarHBondContact CB-O 3.39Å; W372-P573 WeakPolarHBondContact O-CD 3.48Å; W372-E574 HydrophobicContact CE3-CB 4.38Å; W372-E574 HydrophobicContact CH2-CG 4.15Å; W372-E574 HydrophobicContact CZ3-CB 4.27Å; W372-E574 HydrophobicContact CZ3-CG 4.15Å
373V98.7Very high96.3Very high11 Ų1138.6 Ų38.67%0.06722%0.22CC..EExtended strand (participates in β ladder)trans-122.3127.4-176.3-179.10000108.9Q371 M375 V378 I464 V465 V467 K553Q371-V373 HydrophobicContact CB-CG2 4.22Å; V373-M375 HydrophobicContact CB-SD 4.48Å; V373-M375 HydrophobicContact CG1-CG 4.27Å; V373-M375 HydrophobicContact CG1-SD 3.84Å; V373-M375 PolarHBondContact O-N 3.21Å; V373-V378 HydrophobicContact CG1-CG2 3.6Å; V373-I464 WeakPolarHBondContact O-CA 3.25Å; V373-V465 PolarHBondContact N-O 3.3Å; V373-V465 PolarHBondContact O-N 3.25Å; V373-V467 HydrophobicContact CG2-CG1 4.33Å; V373-V467 HydrophobicContact CG2-CG2 3.66Å; V373-K553 HydrophobicContact CG1-CG 4.35Å; V373-K553 HydrophobicContact CG2-CD 4.23Å; V373-K553 HydrophobicContact CG2-CG 4.24Å
374N98.6Very high95.9Very high57 Ų5741.9 Ų41.931%0.30524%0.235SC..EExtended strand (participates in β ladder)trans-7495.6165.2-175-1.6000109.3T376 A377 V378 Q463 I464 P573N374-T376 PolarHBondContact O-N 3.18Å; N374-T376 PolarHBondContact OD1-N 3.47Å; N374-T376 VanDerWaalsContact OD1-N 3.15Å; N374-T376 PolarHBondContact OD1-OG1 2.83Å; N374-A377 PolarHBondContact O-N 3.05Å; N374-V378 WeakPolarHBondContact O-CG2 3.31Å; N374-Q463 CarbonylContact C-O 3.49Å; N374-Q463 WeakPolarHBondContact CA-O 3.41Å; N374-Q463 PolarHBondContact OD1-O 3.19Å; N374-I464 HydrophobicContact CB-CD1 3.68Å; N374-P573 HydrophobicContact CB-CG 4.25Å
375M98.5Very high95.8Very high0 Ų046.6 Ų46.60%026%0.256CS..THydrogen-bonded Turntrans-71-6.2-176.4-76.6-63.5-66.300113.5V373 A377 V378 T390 Q463 V465 Y542 T546 A549 Y550V373-M375 HydrophobicContact CB-SD 4.48Å; V373-M375 HydrophobicContact CG1-CG 4.27Å; V373-M375 HydrophobicContact CG1-SD 3.84Å; V373-M375 PolarHBondContact O-N 3.21Å; M375-A377 VanDerWaalsContact C-N 3.32Å; M375-A377 PolarHBondContact O-N 2.75Å; M375-V378 HydrophobicContact SD-CG2 3.99Å; M375-T390 HydrophobicContact CE-CG2 4.37Å; M375-T390 WeakPolarHBondContact O-CB 3.44Å; M375-T390 PolarHBondContact O-OG1 3.39Å; M375-Q463 PolarHBondContact N-O 3.04Å; M375-V465 HydrophobicContact CB-CG2 3.98Å; M375-V465 HydrophobicContact CG-CB 3.73Å; M375-V465 HydrophobicContact CG-CG1 4.4Å; M375-V465 HydrophobicContact CG-CG2 3.62Å; M375-Y542 HydrophobicContact CB-CD1 3.91Å; M375-Y542 HydrophobicContact CB-CD2 3.91Å; M375-Y542 HydrophobicContact CB-CE1 3.77Å; M375-Y542 HydrophobicContact CB-CE2 3.75Å; M375-Y542 HydrophobicContact CB-CG 3.98Å; M375-Y542 HydrophobicContact CE-CD2 3.93Å; M375-Y542 HydrophobicContact CE-CE2 4.47Å; M375-Y542 HydrophobicContact CE-CG 4.43Å; M375-Y542 HydrophobicContact CG-CD2 4.45Å; M375-Y542 HydrophobicContact CG-CE2 4.19Å; M375-T546 HydrophobicContact CE-CG2 4.47Å; M375-A549 HydrophobicContact CE-CB 4.02Å; M375-Y550 HydrophobicContact CE-CD1 4.29Å; M375-Y550 HydrophobicContact CE-CD2 4.29Å; M375-Y550 HydrophobicContact CE-CE1 3.88Å; M375-Y550 HydrophobicContact CE-CE2 3.9Å; M375-Y550 HydrophobicContact CE-CG 4.48Å; M375-Y550 HydrophobicContact SD-CE1 4.07Å
376T97.8Very high95.6Very high24 Ų2449.9 Ų49.915%0.14727%0.269CS..THydrogen-bonded Turntrans-82.8-7.4179.175.80000114.4N374 C391 Q463N374-T376 PolarHBondContact O-N 3.18Å; N374-T376 PolarHBondContact OD1-N 3.47Å; N374-T376 VanDerWaalsContact OD1-N 3.15Å; N374-T376 PolarHBondContact OD1-OG1 2.83Å; T376-C391 WeakPolarHBondContact CA-O 3.36Å; T376-Q463 HydrophobicContact CG2-CB 3.75Å; T376-Q463 HydrophobicContact CG2-CG 3.72Å
377A93.6Very high95.5Very high65 Ų6553.7 Ų53.754%0.53729%0.293SS..SBendtrans-149.633.7-171.800000112.7N374 M375 T379 T390N374-A377 PolarHBondContact O-N 3.05Å; M375-A377 VanDerWaalsContact C-N 3.32Å; M375-A377 PolarHBondContact O-N 2.75Å; A377-T379 PolarHBondContact O-N 3.1Å; A377-T390 PolarHBondContact N-OG1 3.49Å
378V97.9Very high95.5Very high11 Ų1152.1 Ų52.17%0.06729%0.288CS..  trans-81118.3176.4-178.30000108.8V373 N374 M375 V380 S389 T390 A549V373-V378 HydrophobicContact CG1-CG2 3.6Å; N374-V378 WeakPolarHBondContact O-CG2 3.31Å; M375-V378 HydrophobicContact SD-CG2 3.99Å; V378-V380 HydrophobicContact CG1-CG2 4.09Å; V378-S389 CarbonylContact O-C 3.51Å; V378-S389 VanDerWaalsContact O-CA 3.24Å; V378-S389 WeakPolarHBondContact O-CA 3.32Å; V378-T390 HydrophobicContact CB-CG2 4.1Å; V378-T390 PolarHBondContact N-OG1 3.25Å; V378-T390 PolarHBondContact O-N 3.38Å; V378-A549 HydrophobicContact CB-CB 4.04Å; V378-A549 HydrophobicContact CG1-CB 3.8Å
379T97.1Very high95.4Very high89 Ų8953.8 Ų53.855%0.54630%0.302SS..EExtended strand (participates in β ladder)trans-101.3129176.5-58.30000110A377 T387 V388A377-T379 PolarHBondContact O-N 3.1Å; T379-T387 HydrophobicContact CG2-CG2 3.2Å; T379-V388 CarbonylContact C-O 3.51Å; T379-V388 WeakPolarHBondContact CA-O 3.47Å
380V95.7Very high95.4Very high13 Ų1354.1 Ų54.18%0.07930%0.304CS..EExtended strand (participates in β ladder)trans-125.9122.7179.3-172.70000109.7V378 I382 T387 V388 T548 H552V378-V380 HydrophobicContact CG1-CG2 4.09Å; V380-I382 HydrophobicContact CG1-CD1 4.3Å; V380-I382 PolarHBondContact O-N 2.71Å; V380-T387 WeakPolarHBondContact O-CA 3.36Å; V380-V388 HydrophobicContact CB-CG2 4.18Å; V380-V388 PolarHBondContact N-O 3.46Å; V380-V388 PolarHBondContact O-N 3.27Å; V380-T548 HydrophobicContact CB-CG2 4.08Å; V380-T548 HydrophobicContact CG1-CG2 3.97Å; V380-T548 HydrophobicContact CG2-CG2 4.3Å; V380-H552 HydrophobicContact CG1-CB 4.07Å; V380-H552 HydrophobicContact CG2-CB 3.91Å
381K94.6Very high95.4Very high123 Ų12353.6 Ų53.654%0.53530%0.302SS..EExtended strand (participates in β ladder)trans-80.9108171.6-173176175.4-168.30108.9N383 D384K381-N383 WeakPolarHBondContact CE-O 3.4Å; K381-N383 WeakPolarHBondContact CG-O 3.31Å; K381-D384 VanDerWaalsContact CE-CA 3.41Å; K381-D384 WeakPolarHBondContact CE-OD1 3.29Å; K381-D384 IonicContact NZ-OD1 3.73Å; K381-D384 PolarHBondContact NZ-OD1 2.82Å
382I88.4Confident95.4Very high89 Ų8957.4 Ų57.446%0.45632%0.319SS..  trans-74.7-42.7179.4-60.3-60.4000110.5V380 H386 V388 T548V380-I382 HydrophobicContact CG1-CD1 4.3Å; V380-I382 PolarHBondContact O-N 2.71Å; I382-H386 PolarHBondContact N-O 3Å; I382-V388 HydrophobicContact CD1-CG2 3.98Å; I382-V388 HydrophobicContact CG1-CG1 4.08Å; I382-V388 HydrophobicContact CG1-CG2 3.92Å; I382-T548 HydrophobicContact CD1-CG2 3.49Å; I382-T548 VanDerWaalsContact CD1-CG2 3.49Å
383N89.4Confident95.4Very high80 Ų8056.1 Ų56.143%0.42831%0.314SS..SBendtrans-152.3-174.9175.16439000109.7K381 T385 H386K381-N383 WeakPolarHBondContact CE-O 3.4Å; K381-N383 WeakPolarHBondContact CG-O 3.31Å; N383-T385 PolarHBondContact O-N 3.06Å; N383-T385 VanDerWaalsContact O-N 3.17Å; N383-T385 PolarHBondContact OD1-N 3.35Å; N383-T385 PolarHBondContact OD1-OG1 3.17Å; N383-H386 PolarHBondContact N-O 2.94Å; N383-H386 PolarHBondContact O-N 3.25Å; N383-H386 VanDerWaalsContact OD1-CB 3.26Å; N383-H386 WeakPolarHBondContact OD1-CB 3.18Å; N383-H386 PolarHBondContact OD1-N 2.78Å
384D87.7Confident95.4Very high140 Ų14055.6 Ų55.675%0.74931%0.311SS*.SBendtrans-61.6-24.5-175.2-74.2-37.7000115.8K381K381-D384 VanDerWaalsContact CE-CA 3.41Å; K381-D384 WeakPolarHBondContact CE-OD1 3.29Å; K381-D384 IonicContact NZ-OD1 3.73Å; K381-D384 PolarHBondContact NZ-OD1 2.82Å
385T90.1Very high95.3Very high137 Ų13752.9 Ų52.984%0.8430%0.296SS*.SBendtrans-113.3-9.4-175.257.80000113.5N383N383-T385 PolarHBondContact O-N 3.06Å; N383-T385 VanDerWaalsContact O-N 3.17Å; N383-T385 PolarHBondContact OD1-N 3.35Å; N383-T385 PolarHBondContact OD1-OG1 3.17Å
386H92.3Very high95.3Very high97 Ų9752.9 Ų52.945%0.44930%0.296SS..  trans-128.7116.3-173.2-16465.7000111.9I382 N383 V388I382-H386 PolarHBondContact N-O 3Å; N383-H386 PolarHBondContact N-O 2.94Å; N383-H386 PolarHBondContact O-N 3.25Å; N383-H386 VanDerWaalsContact OD1-CB 3.26Å; N383-H386 WeakPolarHBondContact OD1-CB 3.18Å; N383-H386 PolarHBondContact OD1-N 2.78Å; H386-V388 VanDerWaalsContact NE2-CG1 3.33Å; H386-V388 WeakPolarHBondContact NE2-CG1 3.37Å
387T95.3Very high95.2Very high80 Ų8052 Ų5249%0.49129%0.29SS..EExtended strand (participates in β ladder)trans-119.9134.6175.4-62.70000108.4T379 V380T379-T387 HydrophobicContact CG2-CG2 3.2Å; V380-T387 WeakPolarHBondContact O-CA 3.36Å
388V96.1Very high95.3Very high11 Ų1149 Ų497%0.06727%0.265CS..EExtended strand (participates in β ladder)trans-119.1157.2179-58.90000109.9T379 V380 I382 H386 H545 T548T379-V388 CarbonylContact C-O 3.51Å; T379-V388 WeakPolarHBondContact CA-O 3.47Å; V380-V388 HydrophobicContact CB-CG2 4.18Å; V380-V388 PolarHBondContact N-O 3.46Å; V380-V388 PolarHBondContact O-N 3.27Å; I382-V388 HydrophobicContact CD1-CG2 3.98Å; I382-V388 HydrophobicContact CG1-CG1 4.08Å; I382-V388 HydrophobicContact CG1-CG2 3.92Å; H386-V388 VanDerWaalsContact NE2-CG1 3.33Å; H386-V388 WeakPolarHBondContact NE2-CG1 3.37Å; V388-H545 HydrophobicContact CB-CB 4.4Å; V388-H545 HydrophobicContact CG2-CB 4.12Å; V388-T548 HydrophobicContact CG2-CG2 4.04Å
389S97.1Very high95.2Very high57 Ų5750.5 Ų50.540%0.39927%0.271SS..EExtended strand (participates in β ladder)trans-132156.5175.260.50000111.9V378V378-S389 CarbonylContact O-C 3.51Å; V378-S389 VanDerWaalsContact O-CA 3.24Å; V378-S389 WeakPolarHBondContact O-CA 3.32Å
390T98.6Very high95Very high6 Ų647.1 Ų47.14%0.03725%0.252CS..  trans-76.5170165.155.80000111.7M375 A377 V378 A549M375-T390 HydrophobicContact CE-CG2 4.37Å; M375-T390 WeakPolarHBondContact O-CB 3.44Å; M375-T390 PolarHBondContact O-OG1 3.39Å; A377-T390 PolarHBondContact N-OG1 3.49Å; V378-T390 HydrophobicContact CB-CG2 4.1Å; V378-T390 PolarHBondContact N-OG1 3.25Å; V378-T390 PolarHBondContact O-N 3.38Å; T390-A549 HydrophobicContact CG2-CB 3.44Å; T390-A549 VanDerWaalsContact CG2-CB 3.44Å
391C98.6Very high94.9Very high3 Ų346.6 Ų46.62%0.0225%0.249CC..  trans-114.3163-177.4-48.40000111.8T376 C441 H442 Y542T376-C391 WeakPolarHBondContact CA-O 3.36Å; C391-C441 WeakPolarHBondContact CA-SG 3.09Å; C391-C441 HydrophobicContact CB-CB 3.91Å; C391-C441 WeakPolarHBondContact CB-SG 3.2Å; C391-C441 WeakPolarHBondContact SG-CB 3.43Å; C391-C441 PolarHBondContact SG-O 2.98Å; C391-C441 CovalentContact SG-SG 2.03Å; C391-C441 PolarHBondContact SG-SG 3.43Å; C391-H442 VanDerWaalsContact CB-NE2 3.29Å; C391-H442 WeakPolarHBondContact CB-NE2 3.29Å; C391-Y542 PolarHBondContact N-O 3.2Å
392K98.4Very high94.9Very high86 Ų8641.2 Ų41.237%0.37423%0.229SC..SBendtrans-57.7145.4160.6-72.6-178.5-178.2174.50109.9A394 H442 E453K392-A394 PolarHBondContact O-N 3.43Å; K392-H442 PolarHBondContact O-NE2 2.87Å; K392-E453 HydrophobicContact CD-CG 4.07Å
393P98.5Very high95.3Very high0 Ų037.7 Ų37.70%021%0.211CC..  trans-63.5130.8-171.921.6-32000112.7T451 G452 H461 I541 Y542P393-T451 CarbonylContact O-C 3.58Å; P393-T451 PolarHBondContact O-N 2.9Å; P393-T451 VanDerWaalsContact O-N 3.12Å; P393-T451 PolarHBondContact O-OG1 3.06Å; P393-G452 PolarHBondContact O-N 3.02Å; P393-H461 HydrophobicContact CB-CB 3.74Å; P393-H461 HydrophobicContact CG-CB 3.68Å; P393-I541 CarbonylContact C-O 3.54Å; P393-I541 WeakPolarHBondContact CA-O 3.06Å; P393-I541 HydrophobicContact CB-CB 4.05Å; P393-I541 HydrophobicContact CB-CD1 3.96Å; P393-I541 HydrophobicContact CB-CG1 4.16Å; P393-Y542 HydrophobicContact CB-CD1 4.24Å; P393-Y542 HydrophobicContact CB-CE1 3.97Å; P393-Y542 HydrophobicContact CG-CE1 4.25Å
394A98.4Very high95.6Very high0 Ų034 Ų340%019%0.192CC..  trans-145.7143.6173.600000112.9K392 H442 K445 I447 F449 I541K392-A394 PolarHBondContact O-N 3.43Å; A394-H442 WeakPolarHBondContact CB-NE2 3.34Å; A394-K445 PolarHBondContact O-NZ 3.38Å; A394-I447 HydrophobicContact CB-CD1 4.22Å; A394-I447 HydrophobicContact CB-CG1 4.16Å; A394-I447 HydrophobicContact CB-CG2 4.02Å; A394-F449 CarbonylContact C-O 3.53Å; A394-F449 VanDerWaalsContact CA-O 3.26Å; A394-F449 WeakPolarHBondContact CA-O 3.26Å; A394-I541 PolarHBondContact N-O 2.94Å
395L98Very high96Very high0 Ų027.7 Ų27.70%016%0.158CC..EExtended strand (participates in β ladder)trans-100.8137.5175.3-68.6169000110.4L150 F399 L448 F449 T451 I541L150-L395 HydrophobicContact CD1-CD1 4.49Å; L150-L395 HydrophobicContact CD2-CD1 3.59Å; L395-F399 HydrophobicContact CB-CB 4.19Å; L395-F399 HydrophobicContact CB-CD1 4.3Å; L395-F399 HydrophobicContact CB-CG 4.17Å; L395-F399 HydrophobicContact CD1-CD1 3.91Å; L395-F399 HydrophobicContact CD1-CD2 4.14Å; L395-F399 HydrophobicContact CD1-CE1 3.83Å; L395-F399 HydrophobicContact CD1-CE2 4.06Å; L395-F399 HydrophobicContact CD1-CG 4.06Å; L395-F399 HydrophobicContact CD1-CZ 3.9Å; L395-F399 HydrophobicContact CD2-CB 4.36Å; L395-F399 HydrophobicContact CD2-CD2 3.81Å; L395-F399 HydrophobicContact CD2-CE2 4.27Å; L395-F399 HydrophobicContact CD2-CG 4.03Å; L395-F399 HydrophobicContact CG-CD2 4.46Å; L395-F399 HydrophobicContact CG-CG 4.32Å; L395-L448 PolarHBondContact O-N 3.14Å; L395-F449 HydrophobicContact CB-CB 4.36Å; L395-F449 HydrophobicContact CB-CD2 4.38Å; L395-F449 HydrophobicContact CD1-CD2 4.35Å; L395-F449 PolarHBondContact N-O 2.96Å; L395-F449 PolarHBondContact O-N 2.92Å; L395-F449 VanDerWaalsContact O-N 3.12Å; L395-T451 HydrophobicContact CD1-CG2 4.46Å; L395-I541 HydrophobicContact CD2-CG2 3.69Å; L395-I541 HydrophobicContact CG-CG2 4.34Å
396G97.2Very high95.8Very high0 Ų021.9 Ų21.90%013%0.125CC..EExtended strand (participates in β ladder)trans-86.1169.5-18000000113.2S398 F399 P446 A538G396-S398 VanDerWaalsContact C-N 3.3Å; G396-S398 PolarHBondContact O-N 2.84Å; G396-F399 WeakPolarHBondContact O-CB 3.37Å; G396-F399 PolarHBondContact O-N 2.99Å; G396-P446 CarbonylContact C-O 3.52Å; G396-P446 WeakPolarHBondContact CA-O 3.37Å; G396-A538 PolarHBondContact N-O 2.86Å
397H95.5Very high95.2Very high5 Ų518.2 Ų18.22%0.02311%0.113CC..G310 helixtrans-52.9-45.3175.9-82.5-130.8000112.6F399 A400 F412 A416 D420 D424 P446H397-F399 PolarHBondContact O-N 3.49Å; H397-A400 PolarHBondContact O-N 2.88Å; H397-F412 HydrophobicContact CB-CD1 3.96Å; H397-F412 HydrophobicContact CB-CE1 3.99Å; H397-F412 AromaticContact CG-CE1 3.91Å; H397-F412 AromaticContact ND1-CE1 3.56Å; H397-F412 VanDerWaalsContact O-CD1 3.31Å; H397-F412 WeakPolarHBondContact O-CD1 3.2Å; H397-A416 HydrophobicContact CB-CB 4.2Å; H397-D420 PolarHBondContact CE1-N 3.36Å; H397-D424 IonicContact CE1-OD1 3.34Å; H397-D424 IonicContact NE2-OD1 2.79Å; H397-D424 PolarHBondContact NE2-OD1 3.33Å; H397-P446 HydrophobicContact CB-CG 4.09Å; H397-P446 PolarHBondContact CD2-O 3.24Å; H397-P446 VanDerWaalsContact CD2-O 3.27Å; H397-P446 PolarHBondContact N-O 2.56Å
398S96.5Very high94.4Very high1 Ų115 Ų151%0.00710%0.097CC..G310 helixtrans-67.7-5.5179.9-62.80000115.2G396 A400 A401 T413 Q414 G415 A416 Q533 Y535G396-S398 VanDerWaalsContact C-N 3.3Å; G396-S398 PolarHBondContact O-N 2.84Å; S398-A400 VanDerWaalsContact C-N 3.29Å; S398-A401 WeakPolarHBondContact O-CB 3.29Å; S398-A401 PolarHBondContact O-N 3.11Å; S398-T413 PolarHBondContact OG-O 3.45Å; S398-Q414 WeakPolarHBondContact OG-CA 3.46Å; S398-G415 PolarHBondContact OG-N 2.84Å; S398-G415 VanDerWaalsContact OG-N 3.15Å; S398-A416 PolarHBondContact OG-N 2.68Å; S398-A416 VanDerWaalsContact OG-N 3.12Å; S398-Q533 WeakPolarHBondContact CB-O 3.48Å; S398-Q533 PolarHBondContact OG-O 3.33Å; S398-Q533 VanDerWaalsContact OG-O 3.07Å; S398-Y535 WeakPolarHBondContact O-CD2 3.47Å
399F95.8Very high93.2Very high43 Ų4318.9 Ų18.919%0.18912%0.117CC..G310 helixtrans-61-41.4165164.8-101.9000110.8L395 G396 H397 A401 G402 F449 H522 Y535L395-F399 HydrophobicContact CB-CB 4.19Å; L395-F399 HydrophobicContact CB-CD1 4.3Å; L395-F399 HydrophobicContact CB-CG 4.17Å; L395-F399 HydrophobicContact CD1-CD1 3.91Å; L395-F399 HydrophobicContact CD1-CD2 4.14Å; L395-F399 HydrophobicContact CD1-CE1 3.83Å; L395-F399 HydrophobicContact CD1-CE2 4.06Å; L395-F399 HydrophobicContact CD1-CG 4.06Å; L395-F399 HydrophobicContact CD1-CZ 3.9Å; L395-F399 HydrophobicContact CD2-CB 4.36Å; L395-F399 HydrophobicContact CD2-CD2 3.81Å; L395-F399 HydrophobicContact CD2-CE2 4.27Å; L395-F399 HydrophobicContact CD2-CG 4.03Å; L395-F399 HydrophobicContact CG-CD2 4.46Å; L395-F399 HydrophobicContact CG-CG 4.32Å; G396-F399 WeakPolarHBondContact O-CB 3.37Å; G396-F399 PolarHBondContact O-N 2.99Å; H397-F399 PolarHBondContact O-N 3.49Å; F399-A401 PolarHBondContact O-N 2.8Å; F399-G402 PolarHBondContact O-N 3.38Å; F399-F449 HydrophobicContact CD1-CD2 4.44Å; F399-F449 HydrophobicContact CD1-CE2 4.38Å; F399-F449 HydrophobicContact CE1-CE2 4.35Å; F399-H522 AromaticContact CE2-CE1 3.85Å; F399-Y535 HydrophobicContact CD2-CE2 4.13Å; F399-Y535 VanDerWaalsContact O-CE2 3.25Å; F399-Y535 WeakPolarHBondContact O-CE2 3.45Å
400A93.3Very high92.1Very high19 Ų1920.8 Ų20.816%0.15712%0.122CC..G310 helixtrans-75.6-5.9-179.800000113.5H397 S398 G402 G408 F412 L448H397-A400 PolarHBondContact O-N 2.88Å; S398-A400 VanDerWaalsContact C-N 3.29Å; A400-G402 VanDerWaalsContact C-N 3.34Å; A400-G408 WeakPolarHBondContact O-CA 3.25Å; A400-F412 HydrophobicContact CB-CB 4.18Å; A400-F412 HydrophobicContact CB-CD1 4.2Å; A400-F412 HydrophobicContact CB-CD2 3.4Å; A400-F412 HydrophobicContact CB-CE1 4.41Å; A400-F412 HydrophobicContact CB-CE2 3.66Å; A400-F412 HydrophobicContact CB-CG 3.68Å; A400-F412 HydrophobicContact CB-CZ 4.15Å; A400-L448 HydrophobicContact CB-CD2 3.63Å
401A93.4Very high91.1Very high1 Ų126 Ų261%0.00815%0.15CC..G310 helixtrans-78.8-18.717600000113S398 F399 G408 F412 T413 Q414S398-A401 WeakPolarHBondContact O-CB 3.29Å; S398-A401 PolarHBondContact O-N 3.11Å; F399-A401 PolarHBondContact O-N 2.8Å; A401-G408 PolarHBondContact O-N 3.29Å; A401-F412 WeakPolarHBondContact CA-O 3.49Å; A401-F412 HydrophobicContact CB-CB 3.92Å; A401-F412 VanDerWaalsContact CB-O 3.26Å; A401-F412 WeakPolarHBondContact CB-O 3.04Å; A401-T413 VanDerWaalsContact CB-C 3.45Å; A401-Q414 HydrophobicContact CB-CG 3.87Å
402G94.3Very high90.5Very high11 Ų1126.6 Ų26.611%0.11315%0.152CC..EExtended strand (participates in β ladder)trans61.5-157.1-16900000112.1F399 A400 G406 Q414 Y535F399-G402 PolarHBondContact O-N 3.38Å; A400-G402 VanDerWaalsContact C-N 3.34Å; G402-G406 WeakPolarHBondContact CA-O 3.48Å; G402-Q414 PolarHBondContact O-NE2 3.16Å; G402-Y535 WeakPolarHBondContact O-CD2 3.44Å
403T96.1Very high90.1Very high14 Ų1425.1 Ų25.19%0.08615%0.15CC..EExtended strand (participates in β ladder)trans-128.5-179.917970.70000111D405 G406 G407 Y535T403-D405 PolarHBondContact O-N 3.17Å; T403-D405 PolarHBondContact OG1-N 3.41Å; T403-D405 VanDerWaalsContact OG1-N 3.14Å; T403-G406 PolarHBondContact N-O 2.81Å; T403-G406 CarbonylContact O-C 3.31Å; T403-G406 PolarHBondContact O-N 3.35Å; T403-G406 VanDerWaalsContact O-N 3.14Å; T403-G407 WeakPolarHBondContact O-CA 3.24Å; T403-G407 PolarHBondContact O-N 2.83Å; T403-G407 VanDerWaalsContact O-N 3.15Å; T403-Y535 HydrophobicContact CG2-CD1 3.29Å; T403-Y535 HydrophobicContact CG2-CD2 4.13Å; T403-Y535 HydrophobicContact CG2-CE1 3.83Å; T403-Y535 HydrophobicContact CG2-CG 3.46Å; T403-Y535 VanDerWaalsContact CG2-CG 3.46Å
404I96.4Very high89.8Confident4 Ų425.2 Ų25.22%0.02115%0.151CC..THydrogen-bonded Turntrans-66-14.9171.166.6-176.9000112.9R200 T297 P303 Q328 A329R200-I404 HydrophobicContact CB-CD1 3.57Å; R200-I404 HydrophobicContact CB-CG1 3.89Å; T297-I404 HydrophobicContact CG2-CD1 4.43Å; P303-I404 HydrophobicContact CB-CB 4Å; P303-I404 HydrophobicContact CB-CD1 4.02Å; P303-I404 HydrophobicContact CB-CG2 3.76Å; P303-I404 HydrophobicContact CG-CD1 3.99Å; P303-I404 HydrophobicContact CG-CG2 4.33Å; Q328-I404 WeakPolarHBondContact CA-O 3.07Å; A329-I404 HydrophobicContact CB-CB 4.09Å; A329-I404 HydrophobicContact CB-CD1 3.81Å; A329-I404 HydrophobicContact CB-CG1 3.82Å; A329-I404 PolarHBondContact N-O 3.35Å
405D95.3Very high89.6Confident7 Ų726.2 Ų26.24%0.03716%0.161CC..THydrogen-bonded Turntrans-85.9-14.5175.6-54.9-46000112.2Y68 R200 V248 T297 N299 T403Y68-D405 VanDerWaalsContact CE1-O 3.29Å; Y68-D405 WeakPolarHBondContact CE1-O 3.34Å; R200-D405 WeakPolarHBondContact CD-OD2 3.42Å; R200-D405 IonicContact CZ-OD2 3.82Å; R200-D405 IonicContact NE-OD2 3Å; R200-D405 IonicContact NH1-OD2 2.71Å; R200-D405 PolarHBondContact NH1-OD2 2.94Å; V248-D405 HydrophobicContact CG2-CB 4.01Å; T297-D405 VanDerWaalsContact CB-OD1 3.26Å; T297-D405 WeakPolarHBondContact CB-OD1 3.25Å; T297-D405 WeakPolarHBondContact CB-OD2 2.71Å; T297-D405 VanDerWaalsContact OG1-CG 3.31Å; T297-D405 PolarHBondContact OG1-OD1 3.32Å; N299-D405 PolarHBondContact ND2-OD1 2.9Å; T403-D405 PolarHBondContact O-N 3.17Å; T403-D405 PolarHBondContact OG1-N 3.41Å; T403-D405 VanDerWaalsContact OG1-N 3.14Å
406G87.1Confident89.3Confident14 Ų1427.2 Ų27.214%0.14417%0.169CC..EExtended strand (participates in β ladder)trans-178.698.2-179.700000110.1G402 T403G402-G406 WeakPolarHBondContact CA-O 3.48Å; T403-G406 PolarHBondContact N-O 2.81Å; T403-G406 CarbonylContact O-C 3.31Å; T403-G406 PolarHBondContact O-N 3.35Å; T403-G406 VanDerWaalsContact O-N 3.14Å
407G80.1Confident89Confident20 Ų2030.7 Ų30.721%0.20619%0.19CC..EExtended strand (participates in β ladder)trans-75.9149.4-177.400000112.9T403T403-G407 WeakPolarHBondContact O-CA 3.24Å; T403-G407 PolarHBondContact O-N 2.83Å; T403-G407 VanDerWaalsContact O-N 3.15Å
408G78.1Confident88.6Confident14 Ų1438.3 Ų38.314%0.14423%0.226CC..  trans-76.2151.8177.700000113.6A400 A401A400-G408 WeakPolarHBondContact O-CA 3.25Å; A401-G408 PolarHBondContact O-N 3.29Å
409D70.9Confident87.8Confident91 Ų9139.9 Ų39.949%0.48724%0.242SC..SBendtrans-86.9-11.1-176.1-78-47000114.5K325K325-D409 IonicContact NZ-OD1 2.74Å; K325-D409 PolarHBondContact NZ-OD1 3.42Å
410L73.9Confident87.1Confident97 Ų9741 Ų4151%0.50825%0.25SC..SBendtrans-98.218.6-171.5-64.5179.3000114F412 W423L410-F412 HydrophobicContact CB-CD2 3.59Å; L410-F412 HydrophobicContact CB-CE2 3.67Å; L410-F412 HydrophobicContact CD1-CE2 4.24Å; L410-F412 WeakPolarHBondContact O-CD2 3.32Å; L410-F412 PolarHBondContact O-N 2.68Å; L410-W423 HydrophobicContact CB-CH2 4.18Å; L410-W423 HydrophobicContact CB-CZ2 4Å; L410-W423 HydrophobicContact CD1-CH2 3.85Å; L410-W423 HydrophobicContact CD1-CZ2 4.46Å; L410-W423 HydrophobicContact CD1-CZ3 4.38Å; L410-W423 HydrophobicContact CD2-CH2 4.05Å; L410-W423 HydrophobicContact CD2-CZ2 4.5Å; L410-W423 HydrophobicContact CG-CH2 4.25Å
411N76.6Confident86.5Confident117 Ų11745.2 Ų45.263%0.62628%0.276SS*.  trans55.121178-156.541.7000115.2
412F87.4Confident85.9Confident15 Ų1551.6 Ų51.67%0.06630%0.304CS..PPolyproline II helixtrans-66.4144.1165.8-73.7-96.7000109.5T324 H397 A400 A401 L410 W423 L448T324-F412 WeakPolarHBondContact CG2-O 3.14Å; T324-F412 PolarHBondContact OG1-O 3.46Å; H397-F412 HydrophobicContact CB-CD1 3.96Å; H397-F412 HydrophobicContact CB-CE1 3.99Å; H397-F412 AromaticContact CG-CE1 3.91Å; H397-F412 AromaticContact ND1-CE1 3.56Å; H397-F412 VanDerWaalsContact O-CD1 3.31Å; H397-F412 WeakPolarHBondContact O-CD1 3.2Å; A400-F412 HydrophobicContact CB-CB 4.18Å; A400-F412 HydrophobicContact CB-CD1 4.2Å; A400-F412 HydrophobicContact CB-CD2 3.4Å; A400-F412 HydrophobicContact CB-CE1 4.41Å; A400-F412 HydrophobicContact CB-CE2 3.66Å; A400-F412 HydrophobicContact CB-CG 3.68Å; A400-F412 HydrophobicContact CB-CZ 4.15Å; A401-F412 WeakPolarHBondContact CA-O 3.49Å; A401-F412 HydrophobicContact CB-CB 3.92Å; A401-F412 VanDerWaalsContact CB-O 3.26Å; A401-F412 WeakPolarHBondContact CB-O 3.04Å; L410-F412 HydrophobicContact CB-CD2 3.59Å; L410-F412 HydrophobicContact CB-CE2 3.67Å; L410-F412 HydrophobicContact CD1-CE2 4.24Å; L410-F412 WeakPolarHBondContact O-CD2 3.32Å; L410-F412 PolarHBondContact O-N 2.68Å; F412-W423 HydrophobicContact CE1-CB 4.39Å; F412-W423 AromaticContact CE1-CD1 3.78Å; F412-W423 HydrophobicContact CE1-CD2 4.29Å; F412-W423 AromaticContact CE1-CG 3.91Å; F412-W423 HydrophobicContact CE1-CG 3.91Å; F412-W423 AromaticContact CE2-CD2 3.77Å; F412-W423 HydrophobicContact CE2-CD2 3.77Å; F412-W423 AromaticContact CE2-CE2 3.4Å; F412-W423 VanDerWaalsContact CE2-CE2 3.4Å; F412-W423 HydrophobicContact CE2-CE3 4.26Å; F412-W423 HydrophobicContact CE2-CG 4.23Å; F412-W423 HydrophobicContact CE2-CH2 4.16Å; F412-W423 AromaticContact CE2-CZ2 3.63Å; F412-W423 HydrophobicContact CE2-CZ2 3.63Å; F412-W423 HydrophobicContact CE2-CZ3 4.44Å; F412-W423 AromaticContact CE2-NE1 3.66Å; F412-W423 HydrophobicContact CZ-CB 4.13Å; F412-W423 AromaticContact CZ-CD1 3.52Å; F412-W423 AromaticContact CZ-CD2 3.33Å; F412-W423 HydrophobicContact CZ-CD2 3.33Å; F412-W423 AromaticContact CZ-CE2 3.43Å; F412-W423 VanDerWaalsContact CZ-CE2 3.43Å; F412-W423 AromaticContact CZ-CE3 3.93Å; F412-W423 HydrophobicContact CZ-CE3 3.93Å; F412-W423 AromaticContact CZ-CG 3.4Å; F412-W423 HydrophobicContact CZ-CG 3.4Å; F412-W423 VanDerWaalsContact CZ-CG 3.4Å; F412-W423 HydrophobicContact CZ-CZ2 4.12Å; F412-W423 AromaticContact CZ-NE1 3.51Å; F412-L448 HydrophobicContact CE1-CD1 4.17Å; F412-L448 HydrophobicContact CE1-CD2 4.25Å; F412-L448 HydrophobicContact CZ-CD1 3.92Å; F412-L448 HydrophobicContact CZ-CD2 4.06Å
413T88.5Confident85.3Confident54 Ų5454.1 Ų54.133%0.33131%0.31SS..PPolyproline II helixtrans-102.4154.9171.453.50000111.4T324 S398 A401T324-T413 HydrophobicContact CG2-CG2 4.15Å; S398-T413 PolarHBondContact OG-O 3.45Å; A401-T413 VanDerWaalsContact CB-C 3.45Å
414Q93.9Very high84.6Confident3 Ų355.3 Ų55.31%0.01432%0.316CS..THydrogen-bonded Turntrans-73156.8167-64.9-1695500110.2N316 S398 A401 G402 R534N316-Q414 WeakPolarHBondContact CA-O 3.4Å; N316-Q414 PolarHBondContact O-N 3.45Å; N316-Q414 PolarHBondContact OD1-O 3.34Å; N316-Q414 VanDerWaalsContact OD1-O 3.08Å; S398-Q414 WeakPolarHBondContact OG-CA 3.46Å; A401-Q414 HydrophobicContact CB-CG 3.87Å; G402-Q414 PolarHBondContact O-NE2 3.16Å; Q414-R534 HydrophobicContact CB-CB 4.4Å; Q414-R534 HydrophobicContact CB-CG 4.21Å; Q414-R534 VanDerWaalsContact OE1-CZ 3.24Å
415G93.8Very high83Confident20 Ų2057 Ų5721%0.20633%0.334CS..THydrogen-bonded Turntrans88.912.7174.700000114.8S398 V417 V532 Q533S398-G415 PolarHBondContact OG-N 2.84Å; S398-G415 VanDerWaalsContact OG-N 3.15Å; G415-V417 PolarHBondContact O-N 3.37Å; G415-V532 VanDerWaalsContact CA-O 3.31Å; G415-V532 WeakPolarHBondContact CA-O 3.38Å; G415-Q533 VanDerWaalsContact CA-O 3.25Å; G415-Q533 WeakPolarHBondContact CA-O 3.32Å; G415-Q533 PolarHBondContact N-O 2.8Å
416A91.3Very high81.9Confident22 Ų2259.5 Ų59.518%0.18235%0.347CS..  trans-75.9115.6-177.200000111H397 S398 P446 Q533H397-A416 HydrophobicContact CB-CB 4.2Å; S398-A416 PolarHBondContact OG-N 2.68Å; S398-A416 VanDerWaalsContact OG-N 3.12Å; A416-P446 HydrophobicContact CB-CG 4.3Å; A416-P446 WeakPolarHBondContact O-CD 3.42Å; A416-P446 WeakPolarHBondContact O-CG 3.38Å; A416-Q533 PolarHBondContact N-O 2.96Å; A416-Q533 WeakPolarHBondContact O-CB 3.2Å
417V90.8Very high81.7Confident73 Ų7359.6 Ų59.644%0.44234%0.343SS..  trans-105.8-7.5173.9-64.30000113.1G415 P444 Q533G415-V417 PolarHBondContact O-N 3.37Å; V417-P444 HydrophobicContact CB-CB 4.5Å; V417-Q533 HydrophobicContact CG1-CB 4.11Å; V417-Q533 HydrophobicContact CG1-CG 4.21Å
418E87.4Confident81.9Confident164 Ų16461.4 Ų61.477%0.76635%0.348SS*.SBendtrans-120.1148.7173.2-66.6-178.1-177.500109.3
419G79.4Confident81.5Confident34 Ų3464.9 Ų64.935%0.35138%0.375SS..  trans-78152.8176.200000111.7
420D81.3Confident81.8Confident66 Ų6667.1 Ų67.135%0.35339%0.386SS..  trans-91.8121.2168.1174.1-97.7000110.2H397 F422 W423 D424H397-D420 PolarHBondContact CE1-N 3.36Å; D420-F422 PolarHBondContact O-N 3.48Å; D420-F422 VanDerWaalsContact O-N 3.16Å; D420-F422 WeakPolarHBondContact OD1-CA 3.38Å; D420-F422 VanDerWaalsContact OD1-CB 3.26Å; D420-F422 WeakPolarHBondContact OD1-CB 3.5Å; D420-F422 PolarHBondContact OD1-N 3.09Å; D420-F422 VanDerWaalsContact OD1-N 3.11Å; D420-W423 HydrophobicContact CB-CB 4.34Å; D420-W423 PolarHBondContact O-N 3.13Å; D420-W423 VanDerWaalsContact OD1-CD1 3.24Å; D420-W423 PolarHBondContact OD1-N 2.92Å; D420-D424 WeakPolarHBondContact O-CB 3.44Å; D420-D424 PolarHBondContact O-N 3.4Å
421P81.3Confident82.3Confident109 Ų10965.1 Ų65.171%0.70838%0.378SS*.Hα-helixtrans-58-29.7-176.8-27.535000114.7G425P421-G425 PolarHBondContact O-N 3.21Å
422F80.1Confident82.8Confident135 Ų13560.9 Ų60.959%0.59236%0.362SS*.Hα-helixtrans-71-49.6178.4167.6-92000110.8D420 G425 I426D420-F422 PolarHBondContact O-N 3.48Å; D420-F422 VanDerWaalsContact O-N 3.16Å; D420-F422 WeakPolarHBondContact OD1-CA 3.38Å; D420-F422 VanDerWaalsContact OD1-CB 3.26Å; D420-F422 WeakPolarHBondContact OD1-CB 3.5Å; D420-F422 PolarHBondContact OD1-N 3.09Å; D420-F422 VanDerWaalsContact OD1-N 3.11Å; F422-G425 PolarHBondContact O-N 3.42Å; F422-I426 HydrophobicContact CD1-CD1 4.1Å; F422-I426 HydrophobicContact CE1-CD1 3.47Å; F422-I426 VanDerWaalsContact CE1-CD1 3.47Å; F422-I426 HydrophobicContact CE2-CD1 4.07Å; F422-I426 HydrophobicContact CZ-CD1 3.47Å; F422-I426 VanDerWaalsContact CZ-CD1 3.47Å; F422-I426 PolarHBondContact O-N 2.77Å; F422-I426 VanDerWaalsContact O-N 3.07Å
423W81.8Confident82.9Confident63 Ų6364.1 Ų64.124%0.23939%0.385CS..Hα-helixtrans-66.9-36.6176.4-75.5114.6000113.2L410 F412 D420 G425 I426 R427L410-W423 HydrophobicContact CB-CH2 4.18Å; L410-W423 HydrophobicContact CB-CZ2 4Å; L410-W423 HydrophobicContact CD1-CH2 3.85Å; L410-W423 HydrophobicContact CD1-CZ2 4.46Å; L410-W423 HydrophobicContact CD1-CZ3 4.38Å; L410-W423 HydrophobicContact CD2-CH2 4.05Å; L410-W423 HydrophobicContact CD2-CZ2 4.5Å; L410-W423 HydrophobicContact CG-CH2 4.25Å; F412-W423 HydrophobicContact CE1-CB 4.39Å; F412-W423 AromaticContact CE1-CD1 3.78Å; F412-W423 HydrophobicContact CE1-CD2 4.29Å; F412-W423 AromaticContact CE1-CG 3.91Å; F412-W423 HydrophobicContact CE1-CG 3.91Å; F412-W423 AromaticContact CE2-CD2 3.77Å; F412-W423 HydrophobicContact CE2-CD2 3.77Å; F412-W423 AromaticContact CE2-CE2 3.4Å; F412-W423 VanDerWaalsContact CE2-CE2 3.4Å; F412-W423 HydrophobicContact CE2-CE3 4.26Å; F412-W423 HydrophobicContact CE2-CG 4.23Å; F412-W423 HydrophobicContact CE2-CH2 4.16Å; F412-W423 AromaticContact CE2-CZ2 3.63Å; F412-W423 HydrophobicContact CE2-CZ2 3.63Å; F412-W423 HydrophobicContact CE2-CZ3 4.44Å; F412-W423 AromaticContact CE2-NE1 3.66Å; F412-W423 HydrophobicContact CZ-CB 4.13Å; F412-W423 AromaticContact CZ-CD1 3.52Å; F412-W423 AromaticContact CZ-CD2 3.33Å; F412-W423 HydrophobicContact CZ-CD2 3.33Å; F412-W423 AromaticContact CZ-CE2 3.43Å; F412-W423 VanDerWaalsContact CZ-CE2 3.43Å; F412-W423 AromaticContact CZ-CE3 3.93Å; F412-W423 HydrophobicContact CZ-CE3 3.93Å; F412-W423 AromaticContact CZ-CG 3.4Å; F412-W423 HydrophobicContact CZ-CG 3.4Å; F412-W423 VanDerWaalsContact CZ-CG 3.4Å; F412-W423 HydrophobicContact CZ-CZ2 4.12Å; F412-W423 AromaticContact CZ-NE1 3.51Å; D420-W423 HydrophobicContact CB-CB 4.34Å; D420-W423 PolarHBondContact O-N 3.13Å; D420-W423 VanDerWaalsContact OD1-CD1 3.24Å; D420-W423 PolarHBondContact OD1-N 2.92Å; W423-G425 VanDerWaalsContact C-N 3.33Å; W423-I426 HydrophobicContact CE3-CD1 4.18Å; W423-I426 HydrophobicContact CZ3-CD1 4.21Å; W423-I426 PolarHBondContact O-N 2.88Å; W423-R427 WeakPolarHBondContact O-CB 3.47Å; W423-R427 PolarHBondContact O-N 2.93Å
424D81.1Confident83.1Confident39 Ų3961.8 Ų61.821%0.20937%0.37CS..Hα-helixtrans-62.9-41.1174.3-77.8-10000111.3H397 D420 R427 D428H397-D424 IonicContact CE1-OD1 3.34Å; H397-D424 IonicContact NE2-OD1 2.79Å; H397-D424 PolarHBondContact NE2-OD1 3.33Å; D420-D424 WeakPolarHBondContact O-CB 3.44Å; D420-D424 PolarHBondContact O-N 3.4Å; D424-R427 PolarHBondContact O-N 3.35Å; D424-R427 IonicContact OD1-CZ 3.97Å; D424-R427 IonicContact OD1-NH1 2.81Å; D424-R427 PolarHBondContact OD1-NH1 2.03Å; D424-R427 IonicContact OD1-NH2 2.7Å; D424-R427 IonicContact OD2-NH1 3.71Å; D424-D428 WeakPolarHBondContact O-CB 3.2Å; D424-D428 PolarHBondContact O-N 3.1Å
425G62.8Low83.2Confident39 Ų3963.6 Ų63.640%0.40238%0.383SS..Hα-helixtrans-63.5-42.3174.300000113.3P421 F422 W423 D428 A429P421-G425 PolarHBondContact O-N 3.21Å; F422-G425 PolarHBondContact O-N 3.42Å; W423-G425 VanDerWaalsContact C-N 3.33Å; G425-D428 PolarHBondContact O-N 3.14Å; G425-A429 WeakPolarHBondContact O-CB 3.27Å; G425-A429 PolarHBondContact O-N 3.27Å
426I72.4Confident83.3Confident61 Ų6169 Ų6931%0.31341%0.407SS..Hα-helixtrans-63.7-46.6175.7-70.3175.1000110.9F422 W423 D428 A429 L430F422-I426 HydrophobicContact CD1-CD1 4.1Å; F422-I426 HydrophobicContact CE1-CD1 3.47Å; F422-I426 VanDerWaalsContact CE1-CD1 3.47Å; F422-I426 HydrophobicContact CE2-CD1 4.07Å; F422-I426 HydrophobicContact CZ-CD1 3.47Å; F422-I426 VanDerWaalsContact CZ-CD1 3.47Å; F422-I426 PolarHBondContact O-N 2.77Å; F422-I426 VanDerWaalsContact O-N 3.07Å; W423-I426 HydrophobicContact CE3-CD1 4.18Å; W423-I426 HydrophobicContact CZ3-CD1 4.21Å; W423-I426 PolarHBondContact O-N 2.88Å; I426-D428 PolarHBondContact O-N 2.69Å; I426-A429 PolarHBondContact O-N 3.12Å; I426-L430 HydrophobicContact CG2-CD1 3.63Å; I426-L430 HydrophobicContact CG2-CG 4.28Å; I426-L430 WeakPolarHBondContact O-CB 3.18Å; I426-L430 WeakPolarHBondContact O-CG 3.37Å; I426-L430 PolarHBondContact O-N 2.75Å
427R83.5Confident83.5Confident16 Ų1674.9 Ų74.96%0.0643%0.431CS..Hα-helixtrans-55.3-52.3175.2173.7-159.668.7-142.5-11.8110.4W423 D424 A429 L430 V431 G432 P434 I447 L448W423-R427 WeakPolarHBondContact O-CB 3.47Å; W423-R427 PolarHBondContact O-N 2.93Å; D424-R427 PolarHBondContact O-N 3.35Å; D424-R427 IonicContact OD1-CZ 3.97Å; D424-R427 IonicContact OD1-NH1 2.81Å; D424-R427 PolarHBondContact OD1-NH1 2.03Å; D424-R427 IonicContact OD1-NH2 2.7Å; D424-R427 IonicContact OD2-NH1 3.71Å; R427-A429 VanDerWaalsContact C-N 3.28Å; R427-A429 PolarHBondContact O-N 2.75Å; R427-L430 PolarHBondContact O-N 3.37Å; R427-V431 HydrophobicContact CG-CG2 3.81Å; R427-V431 WeakPolarHBondContact O-CG2 3.46Å; R427-V431 PolarHBondContact O-N 3.46Å; R427-G432 PolarHBondContact O-N 3.4Å; R427-P434 VanDerWaalsContact NE-CD 3.26Å; R427-I447 PolarHBondContact NH1-O 3Å; R427-L448 WeakPolarHBondContact CD-O 3.23Å; R427-L448 VanDerWaalsContact CG-O 3.23Å; R427-L448 WeakPolarHBondContact CG-O 3.11Å
428D83.7Confident83.7Confident58 Ų5871.7 Ų71.731%0.3141%0.412SS..Hα-helixtrans-62.6-37.3-175.4-68.4-1.2000111.6D424 G425 I426 G432 P433D424-D428 WeakPolarHBondContact O-CB 3.2Å; D424-D428 PolarHBondContact O-N 3.1Å; G425-D428 PolarHBondContact O-N 3.14Å; I426-D428 PolarHBondContact O-N 2.69Å; D428-G432 VanDerWaalsContact O-CA 3.29Å; D428-G432 WeakPolarHBondContact O-CA 3.45Å; D428-G432 PolarHBondContact O-N 3.08Å; D428-P433 HydrophobicContact CB-CB 4.43Å; D428-P433 VanDerWaalsContact OD1-CA 3.24Å; D428-P433 WeakPolarHBondContact OD1-CA 3.42Å
429A69.2Low84.2Confident87 Ų8767.9 Ų67.972%0.71939%0.393SS*.Hα-helixtrans-71-37176.900000113.6G425 I426 R427G425-A429 WeakPolarHBondContact O-CB 3.27Å; G425-A429 PolarHBondContact O-N 3.27Å; I426-A429 PolarHBondContact O-N 3.12Å; R427-A429 VanDerWaalsContact C-N 3.28Å; R427-A429 PolarHBondContact O-N 2.75Å
430L78Confident85Confident137 Ų13773.9 Ų73.972%0.71741%0.412SS*.Hα-helixtrans-89.6-39.3-174-68.3179.5000113.6I426 R427I426-L430 HydrophobicContact CG2-CD1 3.63Å; I426-L430 HydrophobicContact CG2-CG 4.28Å; I426-L430 WeakPolarHBondContact O-CB 3.18Å; I426-L430 WeakPolarHBondContact O-CG 3.37Å; I426-L430 PolarHBondContact O-N 2.75Å; R427-L430 PolarHBondContact O-N 3.37Å
431V85.1Confident85.8Confident56 Ų5672.5 Ų72.534%0.33941%0.407SS..Hα-helixtrans-132.61.8-169.7-62.60000114R427 M454R427-V431 HydrophobicContact CG-CG2 3.81Å; R427-V431 WeakPolarHBondContact O-CG2 3.46Å; R427-V431 PolarHBondContact O-N 3.46Å; V431-M454 HydrophobicContact CB-CE 3.66Å; V431-M454 HydrophobicContact CB-SD 4.38Å; V431-M454 HydrophobicContact CG1-CE 3.58Å; V431-M454 HydrophobicContact CG2-CE 4.02Å; V431-M454 HydrophobicContact CG2-SD 4.38Å
432G86.3Confident86.6Confident28 Ų2867.3 Ų67.329%0.28937%0.373SS..  trans85.7154.3178.500000113.9R427 D428R427-G432 PolarHBondContact O-N 3.4Å; D428-G432 VanDerWaalsContact O-CA 3.29Å; D428-G432 WeakPolarHBondContact O-CA 3.45Å; D428-G432 PolarHBondContact O-N 3.08Å
433P90.4Very high87.5Confident83 Ų8367.1 Ų67.154%0.53937%0.374SS..PPolyproline II helixtrans-71.8139.318028.4-34000112.2D428D428-P433 HydrophobicContact CB-CB 4.43Å; D428-P433 VanDerWaalsContact OD1-CA 3.24Å; D428-P433 WeakPolarHBondContact OD1-CA 3.42Å
434P92.6Very high88.2Confident4 Ų464.8 Ų64.83%0.02637%0.367CS..PPolyproline II helixtrans-59.8140170.8-17.727.1000110.4R427 K439 I447 E453R427-P434 VanDerWaalsContact NE-CD 3.26Å; P434-K439 HydrophobicContact CB-CG 4.03Å; P434-K439 VanDerWaalsContact O-CE 3.24Å; P434-K439 WeakPolarHBondContact O-CE 3.3Å; P434-I447 HydrophobicContact CB-CD1 4.01Å; P434-I447 HydrophobicContact CB-CG2 4.23Å; P434-I447 HydrophobicContact CG-CB 4.05Å; P434-I447 HydrophobicContact CG-CD1 4.46Å; P434-I447 HydrophobicContact CG-CG2 3.7Å; P434-E453 WeakPolarHBondContact CA-OE2 3.48Å
435S95.4Very high89.1Confident41 Ų4163.3 Ų63.329%0.28736%0.358SS..PPolyproline II helixtrans-62.2153.7177.172.20000112.2Q437 T438 K439 E453S435-Q437 PolarHBondContact O-N 3.41Å; S435-T438 PolarHBondContact O-N 3.01Å; S435-T438 VanDerWaalsContact O-N 3.08Å; S435-T438 WeakPolarHBondContact OG-CB 3.19Å; S435-T438 PolarHBondContact OG-N 3.06Å; S435-T438 PolarHBondContact OG-OG1 2.64Å; S435-T438 VanDerWaalsContact OG-OG1 3.06Å; S435-K439 WeakPolarHBondContact O-CG 3.39Å; S435-K439 PolarHBondContact O-N 2.6Å; S435-E453 VanDerWaalsContact CB-OE1 3.25Å; S435-E453 WeakPolarHBondContact CB-OE1 3.3Å; S435-E453 PolarHBondContact N-OE2 2.87Å; S435-E453 VanDerWaalsContact N-OE2 3.11Å; S435-E453 PolarHBondContact OG-OE1 3.29Å
436N95.8Very high90.7Very high133 Ų13362.1 Ų62.171%0.71134%0.343SS*.Hα-helixtrans-57.7-38.6177.4-70.9-12.1000111.8K439 E440N436-K439 PolarHBondContact O-N 2.86Å; N436-E440 WeakPolarHBondContact O-CB 3.31Å; N436-E440 PolarHBondContact O-N 2.85Å
437Q95.3Very high91.8Very high147 Ų14759.5 Ų59.569%0.68733%0.33SS*.Hα-helixtrans-61-45175.5-175-177.214.600111.6S435 C441S435-Q437 PolarHBondContact O-N 3.41Å; Q437-C441 VanDerWaalsContact O-CB 3.24Å; Q437-C441 WeakPolarHBondContact O-CB 3.47Å; Q437-C441 PolarHBondContact O-N 2.85Å
438T95.5Very high92.4Very high5 Ų559.1 Ų59.13%0.03133%0.329CS..Hα-helixtrans-66.6-41.7178.5-62.70000110.8S435 C441 H442 I447 E453S435-T438 PolarHBondContact O-N 3.01Å; S435-T438 VanDerWaalsContact O-N 3.08Å; S435-T438 WeakPolarHBondContact OG-CB 3.19Å; S435-T438 PolarHBondContact OG-N 3.06Å; S435-T438 PolarHBondContact OG-OG1 2.64Å; S435-T438 VanDerWaalsContact OG-OG1 3.06Å; T438-C441 PolarHBondContact O-N 3.02Å; T438-H442 WeakPolarHBondContact O-CB 3.21Å; T438-H442 PolarHBondContact O-CD2 2.88Å; T438-H442 PolarHBondContact O-N 2.7Å; T438-I447 HydrophobicContact CG2-CD1 3.66Å; T438-E453 PolarHBondContact OG1-OE1 2.94Å
439K96.6Very high92.9Very high85 Ų8559 Ų5937%0.3733%0.326SS..Hα-helixtrans-59.9-48.2175.4-69.8177178.3174.10112.1P434 S435 N436 H442 H443 I447P434-K439 HydrophobicContact CB-CG 4.03Å; P434-K439 VanDerWaalsContact O-CE 3.24Å; P434-K439 WeakPolarHBondContact O-CE 3.3Å; S435-K439 WeakPolarHBondContact O-CG 3.39Å; S435-K439 PolarHBondContact O-N 2.6Å; N436-K439 PolarHBondContact O-N 2.86Å; K439-H442 PolarHBondContact O-N 2.7Å; K439-H443 PolarHBondContact O-N 3.11Å; K439-H443 VanDerWaalsContact O-N 3.16Å; K439-I447 HydrophobicContact CG-CD1 4.23Å
440E97.2Very high94.2Very high160 Ų16055.2 Ų55.275%0.74829%0.294SS*.Hα-helixtrans-63.7-46.2179.4-174.8176.2-173.400111.5N436 H442 H443N436-E440 WeakPolarHBondContact O-CB 3.31Å; N436-E440 PolarHBondContact O-N 2.85Å; E440-H442 VanDerWaalsContact C-N 3.25Å; E440-H442 PolarHBondContact O-N 2.91Å; E440-H443 WeakPolarHBondContact O-CB 3.38Å; E440-H443 PolarHBondContact O-N 2.82Å
441C98Very high95.1Very high36 Ų3648.7 Ų48.724%0.24326%0.26CS..Hα-helixtrans-60.8-36.2178.6-168.10000112.3C391 Q437 T438 P544C391-C441 WeakPolarHBondContact CA-SG 3.09Å; C391-C441 HydrophobicContact CB-CB 3.91Å; C391-C441 WeakPolarHBondContact CB-SG 3.2Å; C391-C441 WeakPolarHBondContact SG-CB 3.43Å; C391-C441 PolarHBondContact SG-O 2.98Å; C391-C441 CovalentContact SG-SG 2.03Å; C391-C441 PolarHBondContact SG-SG 3.43Å; Q437-C441 VanDerWaalsContact O-CB 3.24Å; Q437-C441 WeakPolarHBondContact O-CB 3.47Å; Q437-C441 PolarHBondContact O-N 2.85Å; T438-C441 PolarHBondContact O-N 3.02Å; C441-P544 VanDerWaalsContact O-CD 3.29Å; C441-P544 WeakPolarHBondContact O-CD 3.29Å
442H98.4Very high95.6Very high0 Ų046.2 Ų46.20%025%0.246CC..Hα-helixtrans-84.3-12.2-177.6-92.2-73.7000115.3C391 K392 A394 T438 K439 E440 K445 I447 Y530 I541 G543C391-H442 VanDerWaalsContact CB-NE2 3.29Å; C391-H442 WeakPolarHBondContact CB-NE2 3.29Å; K392-H442 PolarHBondContact O-NE2 2.87Å; A394-H442 WeakPolarHBondContact CB-NE2 3.34Å; T438-H442 WeakPolarHBondContact O-CB 3.21Å; T438-H442 PolarHBondContact O-CD2 2.88Å; T438-H442 PolarHBondContact O-N 2.7Å; K439-H442 PolarHBondContact O-N 2.7Å; E440-H442 VanDerWaalsContact C-N 3.25Å; E440-H442 PolarHBondContact O-N 2.91Å; H442-K445 HydrophobicContact CB-CB 4.26Å; H442-K445 WeakPolarHBondContact O-CB 3.22Å; H442-K445 PolarHBondContact O-N 3.42Å; H442-I447 HydrophobicContact CB-CD1 4.03Å; H442-I447 HydrophobicContact CB-CG1 4.16Å; H442-Y530 PolarHBondContact ND1-OH 3.14Å; H442-Y530 VanDerWaalsContact ND1-OH 3.11Å; H442-Y530 WeakPolarHBondContact O-CE1 3.39Å; H442-Y530 PolarHBondContact O-OH 3.02Å; H442-I541 PolarHBondContact CE1-O 3.01Å; H442-I541 PolarHBondContact NE2-O 3.4Å; H442-G543 PolarHBondContact CE1-N 2.79Å; H442-G543 VanDerWaalsContact CE1-N 3.34Å
443H97.6Very high96.1Very high131 Ų13147.6 Ų47.661%0.60625%0.245SC*.THydrogen-bonded Turntrans-48135.1-176.7-176.5-81000111.8K439 E440K439-H443 PolarHBondContact O-N 3.11Å; K439-H443 VanDerWaalsContact O-N 3.16Å; E440-H443 WeakPolarHBondContact O-CB 3.38Å; E440-H443 PolarHBondContact O-N 2.82Å
444P98.1Very high96.3Very high14 Ų1444.4 Ų44.49%0.09122%0.223CC..THydrogen-bonded Turncis-90.415.37.437.1-38.1000114.8V417 P446 Q533V417-P444 HydrophobicContact CB-CB 4.5Å; P444-P446 WeakPolarHBondContact O-CD 3.38Å; P444-Q533 HydrophobicContact CG-CG 4.49Å
445K98.5Very high96.4Very high8 Ų848.3 Ų48.34%0.03524%0.244CC..  trans-65.5119.2-179.2174.7-175.2-61.8-165.80111.2A394 H442 I447 Y530 Q533 G537 A538 T540A394-K445 PolarHBondContact O-NZ 3.38Å; H442-K445 HydrophobicContact CB-CB 4.26Å; H442-K445 WeakPolarHBondContact O-CB 3.22Å; H442-K445 PolarHBondContact O-N 3.42Å; K445-I447 PolarHBondContact O-N 3.31Å; K445-Y530 HydrophobicContact CB-CE1 4.32Å; K445-Y530 VanDerWaalsContact CB-OH 3.3Å; K445-Y530 WeakPolarHBondContact CB-OH 3.44Å; K445-Y530 VanDerWaalsContact CE-OH 3.23Å; K445-Y530 WeakPolarHBondContact CE-OH 3.28Å; K445-Q533 HydrophobicContact CB-CG 4.49Å; K445-Q533 VanDerWaalsContact CB-OE1 3.29Å; K445-Q533 VanDerWaalsContact CG-OE1 3.26Å; K445-G537 WeakPolarHBondContact CE-O 3.21Å; K445-A538 VanDerWaalsContact CE-O 3.31Å; K445-A538 WeakPolarHBondContact CE-O 3.38Å; K445-A538 PolarHBondContact NZ-O 2.86Å; K445-T540 PolarHBondContact NZ-O 3.4Å
446P96.8Very high96.1Very high14 Ų1456.4 Ų56.49%0.09127%0.268CS..  trans-74.4112.2166.330.8-32.4000108.6G396 H397 A416 P444 L448G396-P446 CarbonylContact C-O 3.52Å; G396-P446 WeakPolarHBondContact CA-O 3.37Å; H397-P446 HydrophobicContact CB-CG 4.09Å; H397-P446 PolarHBondContact CD2-O 3.24Å; H397-P446 VanDerWaalsContact CD2-O 3.27Å; H397-P446 PolarHBondContact N-O 2.56Å; A416-P446 HydrophobicContact CB-CG 4.3Å; A416-P446 WeakPolarHBondContact O-CD 3.42Å; A416-P446 WeakPolarHBondContact O-CG 3.38Å; P444-P446 WeakPolarHBondContact O-CD 3.38Å; P446-L448 PolarHBondContact O-N 2.82Å
447I96.8Very high96Very high7 Ų751.4 Ų51.44%0.03624%0.243CC..EExtended strand (participates in β ladder)trans-72.3119.5-173-63.6172.1000110.5A394 R427 P434 T438 K439 H442 K445A394-I447 HydrophobicContact CB-CD1 4.22Å; A394-I447 HydrophobicContact CB-CG1 4.16Å; A394-I447 HydrophobicContact CB-CG2 4.02Å; R427-I447 PolarHBondContact NH1-O 3Å; P434-I447 HydrophobicContact CB-CD1 4.01Å; P434-I447 HydrophobicContact CB-CG2 4.23Å; P434-I447 HydrophobicContact CG-CB 4.05Å; P434-I447 HydrophobicContact CG-CD1 4.46Å; P434-I447 HydrophobicContact CG-CG2 3.7Å; T438-I447 HydrophobicContact CG2-CD1 3.66Å; K439-I447 HydrophobicContact CG-CD1 4.23Å; H442-I447 HydrophobicContact CB-CD1 4.03Å; H442-I447 HydrophobicContact CB-CG1 4.16Å; K445-I447 PolarHBondContact O-N 3.31Å
448L94.4Very high96.1Very high7 Ų745 Ų454%0.03721%0.214CC..EExtended strand (participates in β ladder)trans-87-42.5168.4-175.862.1000111.6L395 A400 F412 R427 P446L395-L448 PolarHBondContact O-N 3.14Å; A400-L448 HydrophobicContact CB-CD2 3.63Å; F412-L448 HydrophobicContact CE1-CD1 4.17Å; F412-L448 HydrophobicContact CE1-CD2 4.25Å; F412-L448 HydrophobicContact CZ-CD1 3.92Å; F412-L448 HydrophobicContact CZ-CD2 4.06Å; R427-L448 WeakPolarHBondContact CD-O 3.23Å; R427-L448 VanDerWaalsContact CG-O 3.23Å; R427-L448 WeakPolarHBondContact CG-O 3.11Å; P446-L448 PolarHBondContact O-N 2.82Å
449F94.5Very high96.2Very high57 Ų5746.3 Ų46.325%0.2522%0.222CC..EExtended strand (participates in β ladder)trans-131.7116.8177.7-58.9-68.1000110.9A394 L395 F399 T451 M454A394-F449 CarbonylContact C-O 3.53Å; A394-F449 VanDerWaalsContact CA-O 3.26Å; A394-F449 WeakPolarHBondContact CA-O 3.26Å; L395-F449 HydrophobicContact CB-CB 4.36Å; L395-F449 HydrophobicContact CB-CD2 4.38Å; L395-F449 HydrophobicContact CD1-CD2 4.35Å; L395-F449 PolarHBondContact N-O 2.96Å; L395-F449 PolarHBondContact O-N 2.92Å; L395-F449 VanDerWaalsContact O-N 3.12Å; F399-F449 HydrophobicContact CD1-CD2 4.44Å; F399-F449 HydrophobicContact CD1-CE2 4.38Å; F399-F449 HydrophobicContact CE1-CE2 4.35Å; F449-T451 HydrophobicContact CB-CG2 3.86Å; F449-T451 PolarHBondContact O-N 2.99Å; F449-M454 HydrophobicContact CB-SD 4.42Å
450S96.3Very high96.2Very high6 Ų643.8 Ų43.84%0.04221%0.21CC..  trans-8261.5173.9-1650000110.9G452 E453 M454S450-G452 PolarHBondContact O-N 2.9Å; S450-E453 WeakPolarHBondContact O-CA 3.34Å; S450-E453 PolarHBondContact O-N 3.42Å; S450-E453 PolarHBondContact OG-OE2 3.35Å; S450-M454 VanDerWaalsContact O-CG 3.29Å; S450-M454 WeakPolarHBondContact O-CG 3.5Å; S450-M454 PolarHBondContact O-N 2.91Å
451T96.7Very high96.3Very high1 Ų136.2 Ų36.21%0.00618%0.175CC..THydrogen-bonded Turntrans-57.5-24.2-168.751.40000115.2P393 L395 F449 E453 M454 W460 H461P393-T451 CarbonylContact O-C 3.58Å; P393-T451 PolarHBondContact O-N 2.9Å; P393-T451 VanDerWaalsContact O-N 3.12Å; P393-T451 PolarHBondContact O-OG1 3.06Å; L395-T451 HydrophobicContact CD1-CG2 4.46Å; F449-T451 HydrophobicContact CB-CG2 3.86Å; F449-T451 PolarHBondContact O-N 2.99Å; T451-E453 VanDerWaalsContact C-N 3.28Å; T451-M454 PolarHBondContact O-N 2.85Å; T451-W460 HydrophobicContact CG2-CB 4.09Å; T451-W460 HydrophobicContact CG2-CE3 4.24Å; T451-H461 WeakPolarHBondContact CB-ND1 3.49Å; T451-H461 PolarHBondContact OG1-ND1 3.03Å
452G97.1Very high96.3Very high4 Ų434.5 Ų34.54%0.04116%0.163CC..THydrogen-bonded Turntrans-78.8-10.3175.400000114.5P393 S450P393-G452 PolarHBondContact O-N 3.02Å; S450-G452 PolarHBondContact O-N 2.9Å
453E96.6Very high96.3Very high56 Ų5637.8 Ų37.826%0.26218%0.178SC..THydrogen-bonded Turntrans-105.9-2.9173.4-61.3174.8160.300111.1K392 P434 S435 T438 S450 T451K392-E453 HydrophobicContact CD-CG 4.07Å; P434-E453 WeakPolarHBondContact CA-OE2 3.48Å; S435-E453 VanDerWaalsContact CB-OE1 3.25Å; S435-E453 WeakPolarHBondContact CB-OE1 3.3Å; S435-E453 PolarHBondContact N-OE2 2.87Å; S435-E453 VanDerWaalsContact N-OE2 3.11Å; S435-E453 PolarHBondContact OG-OE1 3.29Å; T438-E453 PolarHBondContact OG1-OE1 2.94Å; S450-E453 WeakPolarHBondContact O-CA 3.34Å; S450-E453 PolarHBondContact O-N 3.42Å; S450-E453 PolarHBondContact OG-OE2 3.35Å; T451-E453 VanDerWaalsContact C-N 3.28Å
454M94.6Very high96.4Very high16 Ų1632.3 Ų32.38%0.07915%0.153CC..  trans-105.5105.9-178.4-61.3165.270.200110.1V431 F449 S450 T451 W460V431-M454 HydrophobicContact CB-CE 3.66Å; V431-M454 HydrophobicContact CB-SD 4.38Å; V431-M454 HydrophobicContact CG1-CE 3.58Å; V431-M454 HydrophobicContact CG2-CE 4.02Å; V431-M454 HydrophobicContact CG2-SD 4.38Å; F449-M454 HydrophobicContact CB-SD 4.42Å; S450-M454 VanDerWaalsContact O-CG 3.29Å; S450-M454 WeakPolarHBondContact O-CG 3.5Å; S450-M454 PolarHBondContact O-N 2.91Å; T451-M454 PolarHBondContact O-N 2.85Å; M454-W460 HydrophobicContact CB-CB 4.21Å; M454-W460 HydrophobicContact CB-CD2 4.06Å; M454-W460 HydrophobicContact CB-CG 3.74Å; M454-W460 HydrophobicContact CE-CD2 3.54Å; M454-W460 HydrophobicContact CE-CE3 3.41Å; M454-W460 VanDerWaalsContact CE-CE3 3.41Å; M454-W460 HydrophobicContact CE-CG 4.39Å; M454-W460 HydrophobicContact CE-CH2 3.29Å; M454-W460 HydrophobicContact CE-CZ2 3.43Å; M454-W460 VanDerWaalsContact CE-CZ2 3.43Å; M454-W460 HydrophobicContact CE-CZ3 3.28Å; M454-W460 PolarHBondContact O-N 2.84Å; M454-W460 VanDerWaalsContact O-N 3.08Å; M454-W460 HydrophobicContact SD-CD2 4.39Å; M454-W460 HydrophobicContact SD-CE3 4.24Å; M454-W460 HydrophobicContact SD-CZ3 4.5Å
455N93.4Very high96.4Very high87 Ų8731.7 Ų31.747%0.46515%0.149SC..  trans-119.16-171.4-64.7-63.2000114.9L458N455-L458 CarbonylContact C-O 3.57Å; N455-L458 CarbonylContact O-C 3.59Å; N455-L458 VanDerWaalsContact O-C 3.24Å; N455-L458 WeakPolarHBondContact O-CA 3.35Å; N455-L458 PolarHBondContact O-N 2.85Å
456W90.5Very high96.4Very high210 Ų21031.3 Ų31.380%0.79515%0.147SC*.SBendtrans-113.3137.9178.7-173.691.9000111.5L458 W460W456-L458 VanDerWaalsContact C-N 3.26Å; W456-W460 PolarHBondContact O-NE1 2.8Å
457P93.7Very high96.5Very high29 Ų2930.6 Ų30.619%0.18814%0.143CC..SBendcis-71.9-16.5-6.231.3-36.7000113.6N581 F583P457-N581 HydrophobicContact CB-CB 4.48Å; P457-N581 PolarHBondContact O-ND2 3.29Å; P457-F583 HydrophobicContact CG-CD1 4.17Å; P457-F583 HydrophobicContact CG-CE1 4.2Å
458L96.6Very high96.6Very high13 Ų1330.3 Ų30.37%0.06814%0.141CC..SBendtrans-141.3165.3173.7-71.4171.7000108.8T149 M152 N455 W456 W460 F578 N581 L582T149-L458 PolarHBondContact OG1-N 3.38Å; T149-L458 PolarHBondContact OG1-O 3.03Å; M152-L458 HydrophobicContact CE-CD1 4.03Å; N455-L458 CarbonylContact C-O 3.57Å; N455-L458 CarbonylContact O-C 3.59Å; N455-L458 VanDerWaalsContact O-C 3.24Å; N455-L458 WeakPolarHBondContact O-CA 3.35Å; N455-L458 PolarHBondContact O-N 2.85Å; W456-L458 VanDerWaalsContact C-N 3.26Å; L458-W460 PolarHBondContact O-N 2.96Å; L458-F578 HydrophobicContact CB-CD2 4.48Å; L458-F578 HydrophobicContact CD1-CB 3.93Å; L458-F578 HydrophobicContact CD1-CD2 3.86Å; L458-F578 HydrophobicContact CD1-CG 3.98Å; L458-F578 HydrophobicContact CD2-CB 4.2Å; L458-F578 HydrophobicContact CD2-CD1 3.86Å; L458-F578 HydrophobicContact CD2-CD2 4.16Å; L458-F578 HydrophobicContact CD2-CE1 4.28Å; L458-F578 HydrophobicContact CD2-CG 3.81Å; L458-F578 HydrophobicContact CG-CD2 4.4Å; L458-F578 HydrophobicContact CG-CG 4.45Å; L458-N581 HydrophobicContact CD1-CB 4.26Å; L458-N581 HydrophobicContact CD2-CB 4.08Å; L458-N581 HydrophobicContact CG-CB 3.94Å; L458-L582 HydrophobicContact CD1-CD2 4.07Å
459P97.6Very high96.8Very high31 Ų3130 Ų3020%0.20114%0.14CC..  trans-48.6133.7170.8-29.237000112.5Y148 T149 F578Y148-P459 HydrophobicContact CD1-CB 4.26Å; Y148-P459 WeakPolarHBondContact CD1-O 3.4Å; Y148-P459 HydrophobicContact CE1-CB 4.43Å; T149-P459 PolarHBondContact N-O 2.87Å; T149-P459 VanDerWaalsContact N-O 3.1Å; P459-F578 HydrophobicContact CB-CZ 4.46Å; P459-F578 HydrophobicContact CG-CZ 3.86Å
460W97.5Very high97Very high33 Ų3327.4 Ų27.413%0.12513%0.129CC..SBendtrans-77.8-28.8-176-80.547.5000113.5T149 L150 L153 T451 M454 W456 L458T149-W460 HydrophobicContact CG2-CD2 4.14Å; T149-W460 HydrophobicContact CG2-CG 4.22Å; T149-W460 HydrophobicContact CG2-CZ2 4.22Å; L150-W460 HydrophobicContact CB-CE3 4.38Å; L150-W460 WeakPolarHBondContact CB-O 3.31Å; L150-W460 HydrophobicContact CD1-CE3 4.04Å; L150-W460 HydrophobicContact CD1-CZ3 4.19Å; L150-W460 PolarHBondContact N-O 3.23Å; L153-W460 HydrophobicContact CD1-CH2 3.77Å; L153-W460 HydrophobicContact CD1-CZ2 4.07Å; L153-W460 HydrophobicContact CD1-CZ3 4.14Å; T451-W460 HydrophobicContact CG2-CB 4.09Å; T451-W460 HydrophobicContact CG2-CE3 4.24Å; M454-W460 HydrophobicContact CB-CB 4.21Å; M454-W460 HydrophobicContact CB-CD2 4.06Å; M454-W460 HydrophobicContact CB-CG 3.74Å; M454-W460 HydrophobicContact CE-CD2 3.54Å; M454-W460 HydrophobicContact CE-CE3 3.41Å; M454-W460 VanDerWaalsContact CE-CE3 3.41Å; M454-W460 HydrophobicContact CE-CG 4.39Å; M454-W460 HydrophobicContact CE-CH2 3.29Å; M454-W460 HydrophobicContact CE-CZ2 3.43Å; M454-W460 VanDerWaalsContact CE-CZ2 3.43Å; M454-W460 HydrophobicContact CE-CZ3 3.28Å; M454-W460 PolarHBondContact O-N 2.84Å; M454-W460 VanDerWaalsContact O-N 3.08Å; M454-W460 HydrophobicContact SD-CD2 4.39Å; M454-W460 HydrophobicContact SD-CE3 4.24Å; M454-W460 HydrophobicContact SD-CZ3 4.5Å; W456-W460 PolarHBondContact O-NE1 2.8Å; L458-W460 PolarHBondContact O-N 2.96Å
461H98.5Very high97.1Very high1 Ų127.1 Ų27.11%0.00513%0.127CC..SBendtrans-135.7155.4176.3-90.2157.1000112.9L150 F151 P393 T451 H522 I541L150-H461 WeakPolarHBondContact CD2-NE2 3.38Å; F151-H461 AromaticContact CE2-CD2 3.86Å; F151-H461 AromaticContact CZ-CD2 3.85Å; F151-H461 AromaticContact CZ-NE2 3.73Å; P393-H461 HydrophobicContact CB-CB 3.74Å; P393-H461 HydrophobicContact CG-CB 3.68Å; T451-H461 WeakPolarHBondContact CB-ND1 3.49Å; T451-H461 PolarHBondContact OG1-ND1 3.03Å; H461-H522 AromaticContact CE1-CD2 3.69Å; H461-H522 AromaticContact CE1-NE2 3.55Å; H461-H522 AromaticContact NE2-CD2 3.25Å; H461-H522 PolarHBondContact NE2-CD2 2.83Å; H461-H522 AromaticContact NE2-NE2 2.94Å; H461-H522 PolarHBondContact NE2-NE2 2.93Å; H461-I541 HydrophobicContact CB-CD1 4.49Å
462P98.3Very high97.1Very high0 Ų027.5 Ų27.50%013%0.129CC..  trans-63.8138.1173.725.2-32.4000111.7Y148 V519 T521 Y542Y148-P462 HydrophobicContact CD2-CB 4.25Å; Y148-P462 HydrophobicContact CD2-CG 4.42Å; Y148-P462 HydrophobicContact CE1-CB 4.25Å; Y148-P462 HydrophobicContact CE2-CB 3.59Å; Y148-P462 HydrophobicContact CE2-CG 4.2Å; Y148-P462 VanDerWaalsContact CZ-CA 3.5Å; P462-V519 HydrophobicContact CB-CG2 4.25Å; P462-V519 HydrophobicContact CG-CG2 4.25Å; P462-T521 HydrophobicContact CG-CG2 3.89Å; P462-Y542 PolarHBondContact O-OH 3.04Å
463Q98.3Very high97Very high68 Ų6827.4 Ų27.432%0.31813%0.128SC..SBendtrans-99.3-40.2167.3-60.6-177.4-6.800110.6N374 M375 T376N374-Q463 CarbonylContact C-O 3.49Å; N374-Q463 WeakPolarHBondContact CA-O 3.41Å; N374-Q463 PolarHBondContact OD1-O 3.19Å; M375-Q463 PolarHBondContact N-O 3.04Å; T376-Q463 HydrophobicContact CG2-CB 3.75Å; T376-Q463 HydrophobicContact CG2-CG 3.72Å
464I98.7Very high96.9Very high17 Ų1725.6 Ų25.69%0.08712%0.121CC..EExtended strand (participates in β ladder)trans-93.9124179.2-52.4-43.4000109.2W372 V373 N374 P573 P575W372-I464 HydrophobicContact CB-CG2 3.77Å; W372-I464 HydrophobicContact CG-CG2 4.2Å; V373-I464 WeakPolarHBondContact O-CA 3.25Å; N374-I464 HydrophobicContact CB-CD1 3.68Å; I464-P573 HydrophobicContact CD1-CB 4.08Å; I464-P573 HydrophobicContact CD1-CG 3.57Å; I464-P573 HydrophobicContact CG1-CG 4.34Å; I464-P573 HydrophobicContact CG2-CG 4.35Å; I464-P573 WeakPolarHBondContact CG2-O 3.42Å; I464-P575 HydrophobicContact CB-CB 4.15Å; I464-P575 HydrophobicContact CG2-CB 3.97Å
465V98.8Very high97.1Very high0 Ų024.9 Ų24.90%012%0.118CC..EExtended strand (participates in β ladder)trans-129.2138-171-177.70000110.2V373 M375 P481 V519 T521 Y542V373-V465 PolarHBondContact N-O 3.3Å; V373-V465 PolarHBondContact O-N 3.25Å; M375-V465 HydrophobicContact CB-CG2 3.98Å; M375-V465 HydrophobicContact CG-CB 3.73Å; M375-V465 HydrophobicContact CG-CG1 4.4Å; M375-V465 HydrophobicContact CG-CG2 3.62Å; V465-P481 HydrophobicContact CG1-CB 3.59Å; V465-P481 HydrophobicContact CG1-CG 3.32Å; V465-V519 HydrophobicContact CB-CG1 4.48Å; V465-V519 HydrophobicContact CG1-CG1 3.85Å; V465-T521 HydrophobicContact CG1-CG2 3.93Å; V465-T521 HydrophobicContact CG2-CG2 3.74Å; V465-Y542 HydrophobicContact CG2-CE2 4.23Å; V465-Y542 VanDerWaalsContact CG2-OH 3.26Å; V465-Y542 WeakPolarHBondContact CG2-OH 3.33Å
466D98.8Very high97.3Very high0 Ų020.7 Ų20.70%010%0.096CC..EExtended strand (participates in β ladder)trans-76129.1173.5-64.1-115.1000110.6Q108 R111 H370 W372 P481 N518 V519Q108-D466 PolarHBondContact NE2-OD2 3.03Å; Q108-D466 PolarHBondContact OE1-OD2 3.4Å; Q108-D466 VanDerWaalsContact OE1-OD2 3.1Å; R111-D466 IonicContact CZ-OD1 3.34Å; R111-D466 IonicContact NE-OD1 2.81Å; R111-D466 PolarHBondContact NE-OD1 3.43Å; R111-D466 IonicContact NH2-OD1 2.82Å; R111-D466 PolarHBondContact NH2-OD1 3.05Å; H370-D466 IonicContact CD2-OD1 2.77Å; H370-D466 IonicContact CE1-OD1 3.91Å; H370-D466 IonicContact NE2-OD1 2.76Å; H370-D466 PolarHBondContact NE2-OD1 3.18Å; W372-D466 PolarHBondContact NE1-OD1 2.9Å; W372-D466 VanDerWaalsContact NE1-OD1 3.14Å; D466-P481 WeakPolarHBondContact O-CG 3.31Å; D466-N518 HydrophobicContact CB-CB 3.78Å; D466-V519 HydrophobicContact CB-CG1 4.24Å
467V98.8Very high97.7Very high0 Ų011 Ų110%06%0.06CC..EExtended strand (participates in β ladder)trans-116.9130.6161.2-63.30000108.3H370 Q371 V373 Y550 K553 Y554 L557H370-V467 VanDerWaalsContact CA-O 3.31Å; H370-V467 WeakPolarHBondContact CA-O 3.35Å; Q371-V467 HydrophobicContact CB-CG2 3.92Å; Q371-V467 PolarHBondContact N-O 3.36Å; Q371-V467 PolarHBondContact O-N 2.75Å; V373-V467 HydrophobicContact CG2-CG1 4.33Å; V373-V467 HydrophobicContact CG2-CG2 3.66Å; V467-Y550 HydrophobicContact CG1-CD1 4.09Å; V467-Y550 HydrophobicContact CG1-CE1 4.06Å; V467-K553 HydrophobicContact CG2-CB 4.4Å; V467-Y554 HydrophobicContact CB-CE1 3.99Å; V467-Y554 HydrophobicContact CB-CE2 4.41Å; V467-Y554 HydrophobicContact CG1-CE2 4.15Å; V467-L557 HydrophobicContact CB-CD2 4.37Å; V467-L557 HydrophobicContact CG2-CD1 3.84Å; V467-L557 HydrophobicContact CG2-CD2 4.06Å; V467-L557 WeakPolarHBondContact O-CD2 3.3Å
468Q98.9Very high98Very high0 Ų09.7 Ų9.70%05%0.051CC..EExtended strand (participates in β ladder)trans-149.3140.2-173.8-178-179.523.800112.3H128 D129 V131 V132 A369 H370 A479 N518H128-Q468 PolarHBondContact O-NE2 3.34Å; D129-Q468 VanDerWaalsContact C-NE2 3.27Å; D129-Q468 PolarHBondContact O-NE2 2.97Å; V131-Q468 PolarHBondContact O-NE2 2.69Å; V131-Q468 PolarHBondContact O-OE1 2.52Å; V132-Q468 HydrophobicContact CG2-CG 4.18Å; A369-Q468 VanDerWaalsContact O-CA 3.31Å; A369-Q468 WeakPolarHBondContact O-CA 3.26Å; H370-Q468 HydrophobicContact CB-CB 4.36Å; H370-Q468 HydrophobicContact CB-CG 4.21Å; Q468-A479 HydrophobicContact CB-CB 4.11Å; Q468-A479 PolarHBondContact O-N 2.81Å; Q468-N518 PolarHBondContact OE1-ND2 3.13Å
469I98.9Very high98.1Very high0 Ų09 Ų90%05%0.048CC..EExtended strand (participates in β ladder)trans-126.2131.7168.7-58.5179.9000107.7F368 A369 T471 A476 V477 V478 V496 Y554 L557 A558 I561F368-I469 CarbonylContact C-O 3.5Å; F368-I469 VanDerWaalsContact CA-O 3.24Å; F368-I469 WeakPolarHBondContact CA-O 3.46Å; A369-I469 PolarHBondContact N-O 2.84Å; A369-I469 PolarHBondContact O-N 3.38Å; I469-T471 HydrophobicContact CG2-CG2 4.18Å; I469-A476 HydrophobicContact CG2-CB 4.32Å; I469-V477 WeakPolarHBondContact CA-O 3.29Å; I469-V478 HydrophobicContact CD1-CG2 4.49Å; I469-V478 HydrophobicContact CG1-CG1 4.36Å; I469-V478 HydrophobicContact CG1-CG2 4.32Å; I469-V496 HydrophobicContact CD1-CG1 4.1Å; I469-V496 HydrophobicContact CD1-CG2 4.26Å; I469-Y554 HydrophobicContact CD1-CD1 3.94Å; I469-Y554 HydrophobicContact CG1-CD1 3.74Å; I469-Y554 HydrophobicContact CG1-CE1 4.18Å; I469-L557 HydrophobicContact CD1-CB 3.93Å; I469-L557 HydrophobicContact CG1-CB 4.28Å; I469-L557 HydrophobicContact CG1-CD2 4.32Å; I469-A558 HydrophobicContact CD1-CB 4.01Å; I469-I561 HydrophobicContact CB-CD1 3.75Å; I469-I561 HydrophobicContact CG2-CD1 3.7Å
470I98.8Very high98.1Very high4 Ų47.6 Ų7.62%0.0214%0.038CC..EExtended strand (participates in β ladder)trans-111.7143.9162.664.7173.7000108.8V96 F98 V132 R367 F368 A476 V477V96-I470 HydrophobicContact CB-CB 4.47Å; V96-I470 HydrophobicContact CB-CD1 4.35Å; V96-I470 HydrophobicContact CB-CG2 4.46Å; V96-I470 HydrophobicContact CG1-CB 4.09Å; V96-I470 HydrophobicContact CG1-CG2 4.05Å; V96-I470 HydrophobicContact CG2-CD1 4.47Å; F98-I470 HydrophobicContact CB-CD1 4.18Å; F98-I470 HydrophobicContact CD2-CD1 4.47Å; V132-I470 HydrophobicContact CG2-CD1 4.04Å; V132-I470 HydrophobicContact CG2-CG1 4.26Å; V132-I470 HydrophobicContact CG2-CG2 3.83Å; R367-I470 CarbonylContact O-C 3.58Å; R367-I470 WeakPolarHBondContact O-CA 3.44Å; F368-I470 HydrophobicContact CB-CG2 3.92Å; I470-A476 CarbonylContact O-C 3.24Å; I470-A476 WeakPolarHBondContact O-CA 3.31Å; I470-V477 HydrophobicContact CD1-CB 4.31Å; I470-V477 HydrophobicContact CG1-CB 3.75Å; I470-V477 HydrophobicContact CG1-CG2 4.27Å; I470-V477 PolarHBondContact N-O 3.21Å; I470-V477 PolarHBondContact O-N 3.2Å
471T98.1Very high98.2Very high0 Ų06 Ų60%03%0.032CC..EExtended strand (participates in β ladder)trans-121.7133.9171.973.10000109.9V366 R367 I469 V475 A476 I561V366-T471 VanDerWaalsContact CA-O 3.28Å; V366-T471 WeakPolarHBondContact CA-O 3.37Å; R367-T471 VanDerWaalsContact CB-OG1 3.27Å; R367-T471 WeakPolarHBondContact CB-OG1 3.42Å; R367-T471 PolarHBondContact N-O 3.39Å; R367-T471 PolarHBondContact N-OG1 3.31Å; R367-T471 PolarHBondContact O-N 3.35Å; I469-T471 HydrophobicContact CG2-CG2 4.18Å; T471-V475 CarbonylContact C-O 3.58Å; T471-V475 VanDerWaalsContact CA-O 3.24Å; T471-V475 WeakPolarHBondContact CA-O 3.45Å; T471-A476 HydrophobicContact CG2-CB 3.93Å; T471-I561 HydrophobicContact CG2-CD1 4.34Å; T471-I561 HydrophobicContact CG2-CG2 3.98Å
472V97.4Very high98.2Very high9 Ų96 Ų66%0.0553%0.032CC..EExtended strand (participates in β ladder)trans-115.7100.7169.5177.70000106.2I89 V96 I186 V362 S474 V475I89-V472 HydrophobicContact CB-CG2 4.29Å; I89-V472 HydrophobicContact CD1-CG2 4.36Å; I89-V472 HydrophobicContact CG1-CG2 4.37Å; I89-V472 HydrophobicContact CG2-CG1 3.86Å; I89-V472 HydrophobicContact CG2-CG2 4.41Å; V96-V472 HydrophobicContact CG2-CG2 3.94Å; I186-V472 HydrophobicContact CD1-CG1 3.59Å; V362-V472 HydrophobicContact CG1-CG1 4.37Å; V362-V472 WeakPolarHBondContact CG1-O 3.39Å; V472-S474 PolarHBondContact O-N 2.79Å; V472-S474 VanDerWaalsContact O-N 3.12Å; V472-V475 PolarHBondContact N-O 3.47Å; V472-V475 PolarHBondContact O-N 3.27Å
473G94.9Very high98.2Very high2 Ų26 Ų62%0.0213%0.032CC..THydrogen-bonded Turntrans53.4-118.8-173.700000112.2T363 P365 V475T363-G473 CarbonylContact O-C 3.58Å; T363-G473 WeakPolarHBondContact O-CA 3.43Å; P365-G473 PolarHBondContact O-N 2.69Å; G473-V475 VanDerWaalsContact C-N 3.31Å; G473-V475 PolarHBondContact O-N 3.29Å
474S94.8Very high98.3Very high17 Ų172.8 Ų2.812%0.1192%0.017CC..THydrogen-bonded Turntrans-85.515.217964.60000114.8R188 T363 V472 S509 E510R188-S474 PolarHBondContact NH1-O 3.16Å; R188-S474 PolarHBondContact NH1-OG 3.2Å; T363-S474 PolarHBondContact O-N 2.89Å; V472-S474 PolarHBondContact O-N 2.79Å; V472-S474 VanDerWaalsContact O-N 3.12Å; S474-S509 CarbonylContact O-C 3.6Å; S474-S509 VanDerWaalsContact O-CA 3.23Å; S474-S509 WeakPolarHBondContact O-CA 3.37Å; S474-E510 PolarHBondContact O-N 3.42Å
475V98.1Very high98.3Very high1 Ų12.1 Ų2.11%0.0061%0.014CC..EExtended strand (participates in β ladder)trans-124123.5178.6-177.50000110.2L227 V362 T471 V472 G473 E510L227-V475 HydrophobicContact CD1-CG1 4.18Å; L227-V475 HydrophobicContact CD2-CG1 4.33Å; L227-V475 HydrophobicContact CD2-CG2 3.98Å; V362-V475 HydrophobicContact CG1-CB 4.45Å; V362-V475 HydrophobicContact CG1-CG2 3.89Å; V362-V475 HydrophobicContact CG2-CG2 3.82Å; T471-V475 CarbonylContact C-O 3.58Å; T471-V475 VanDerWaalsContact CA-O 3.24Å; T471-V475 WeakPolarHBondContact CA-O 3.45Å; V472-V475 PolarHBondContact N-O 3.47Å; V472-V475 PolarHBondContact O-N 3.27Å; G473-V475 VanDerWaalsContact C-N 3.31Å; G473-V475 PolarHBondContact O-N 3.29Å; V475-E510 CarbonylContact C-O 3.59Å; V475-E510 WeakPolarHBondContact CA-O 3.24Å
476A98.6Very high98.3Very high0 Ų02.1 Ų2.10%01%0.014CC..EExtended strand (participates in β ladder)trans-106.8124.8175.800000110.5I469 I470 T471 L500 E510 V511 V512I469-A476 HydrophobicContact CG2-CB 4.32Å; I470-A476 CarbonylContact O-C 3.24Å; I470-A476 WeakPolarHBondContact O-CA 3.31Å; T471-A476 HydrophobicContact CG2-CB 3.93Å; A476-L500 HydrophobicContact CB-CD1 3.57Å; A476-E510 PolarHBondContact N-O 2.7Å; A476-V511 HydrophobicContact CB-CG2 4.32Å; A476-V511 WeakPolarHBondContact O-CA 3.38Å; A476-V512 PolarHBondContact O-N 3.37Å
477V98.8Very high98.3Very high7 Ų72.1 Ų2.14%0.0421%0.014CC..EExtended strand (participates in β ladder)trans-102.5116.7173.4-175.20000108.3F98 W242 I469 I470 V512 A514F98-V477 HydrophobicContact CD2-CG1 4.09Å; F98-V477 HydrophobicContact CE2-CG1 3.87Å; W242-V477 HydrophobicContact CH2-CG2 4.18Å; W242-V477 HydrophobicContact CZ2-CG1 4.12Å; W242-V477 HydrophobicContact CZ2-CG2 3.95Å; I469-V477 WeakPolarHBondContact CA-O 3.29Å; I470-V477 HydrophobicContact CD1-CB 4.31Å; I470-V477 HydrophobicContact CG1-CB 3.75Å; I470-V477 HydrophobicContact CG1-CG2 4.27Å; I470-V477 PolarHBondContact N-O 3.21Å; I470-V477 PolarHBondContact O-N 3.2Å; V477-V512 HydrophobicContact CB-CG2 4.11Å; V477-V512 HydrophobicContact CG1-CG2 4.17Å; V477-V512 HydrophobicContact CG2-CG2 3.76Å; V477-A514 HydrophobicContact CG1-CB 3.74Å
478V98.9Very high98.3Very high0 Ų02.1 Ų2.10%01%0.014CC..EExtended strand (participates in β ladder)trans-98.5107.3-179.5-1740000108.7I469 V480 L492 V496 V511 V512 I513 A514 Y554I469-V478 HydrophobicContact CD1-CG2 4.49Å; I469-V478 HydrophobicContact CG1-CG1 4.36Å; I469-V478 HydrophobicContact CG1-CG2 4.32Å; V478-V480 HydrophobicContact CG1-CG2 4.09Å; V478-V480 PolarHBondContact O-N 3.46Å; V478-L492 HydrophobicContact CG1-CD2 3.99Å; V478-V496 HydrophobicContact CG2-CG1 4.12Å; V478-V496 HydrophobicContact CG2-CG2 4.33Å; V478-V511 HydrophobicContact CG2-CG1 3.6Å; V478-V512 PolarHBondContact N-O 3.48Å; V478-I513 HydrophobicContact CB-CD1 3.95Å; V478-I513 HydrophobicContact CG1-CD1 4.26Å; V478-I513 HydrophobicContact CG2-CD1 4.44Å; V478-A514 PolarHBondContact O-N 2.66Å; V478-Y554 HydrophobicContact CG1-CD1 3.5Å; V478-Y554 VanDerWaalsContact CG1-CD1 3.5Å; V478-Y554 HydrophobicContact CG1-CD2 4.37Å; V478-Y554 HydrophobicContact CG1-CE1 3.43Å; V478-Y554 VanDerWaalsContact CG1-CE1 3.43Å; V478-Y554 HydrophobicContact CG1-CE2 4.35Å; V478-Y554 HydrophobicContact CG1-CG 4Å
479A98.9Very high98.3Very high0 Ų02.1 Ų2.10%01%0.014CC..EExtended strand (participates in β ladder)trans-82.195.4-175.400000110.6V132 Q468 Y554V132-A479 HydrophobicContact CG1-CB 3.7Å; V132-A479 HydrophobicContact CG2-CB 4.03Å; Q468-A479 HydrophobicContact CB-CB 4.11Å; Q468-A479 PolarHBondContact O-N 2.81Å; A479-Y554 PolarHBondContact O-OH 2.99Å
480V98.8Very high98.3Very high0 Ų02.6 Ų2.60%02%0.015CC..  trans-90.9127-173.7173.60000111.3V478 G482 M484 L492 I513 A514 G515 L516 S517 I524 Y554V478-V480 HydrophobicContact CG1-CG2 4.09Å; V478-V480 PolarHBondContact O-N 3.46Å; V480-G482 PolarHBondContact O-N 2.95Å; V480-M484 HydrophobicContact CG1-CE 3.61Å; V480-M484 HydrophobicContact CG1-CG 3.94Å; V480-M484 HydrophobicContact CG1-SD 3.87Å; V480-M484 HydrophobicContact CG2-CE 3.99Å; V480-M484 HydrophobicContact CG2-SD 3.98Å; V480-L492 HydrophobicContact CG2-CD2 3.77Å; V480-I513 HydrophobicContact CB-CG2 4.14Å; V480-I513 HydrophobicContact CG2-CD1 4.35Å; V480-I513 HydrophobicContact CG2-CG2 3.73Å; V480-A514 PolarHBondContact N-O 3.28Å; V480-G515 CarbonylContact O-C 3.54Å; V480-L516 PolarHBondContact O-N 3.34Å; V480-S517 PolarHBondContact O-N 3.37Å; V480-I524 HydrophobicContact CG1-CD1 4.35Å; V480-Y554 HydrophobicContact CG2-CE2 4.45Å
481P98.6Very high98.3Very high0 Ų04.5 Ų4.50%02%0.022CC..SBendtrans-80.641.8-174.734.7-39.4000114.6V465 D466 S517 V519 T521 Y550V465-P481 HydrophobicContact CG1-CB 3.59Å; V465-P481 HydrophobicContact CG1-CG 3.32Å; D466-P481 WeakPolarHBondContact O-CG 3.31Å; P481-S517 VanDerWaalsContact CA-O 3.28Å; P481-S517 WeakPolarHBondContact CA-O 3.43Å; P481-V519 CarbonylContact C-O 3.52Å; P481-V519 WeakPolarHBondContact CA-O 3.5Å; P481-V519 HydrophobicContact CB-CG1 3.69Å; P481-V519 WeakPolarHBondContact CB-O 3.33Å; P481-T521 HydrophobicContact CB-CG2 4.43Å; P481-T521 PolarHBondContact O-N 2.84Å; P481-T521 PolarHBondContact O-OG1 2.73Å; P481-Y550 HydrophobicContact CG-CE1 3.85Å; P481-Y550 WeakPolarHBondContact CG-OH 2.87Å
482G98.4Very high98.3Very high0 Ų04.5 Ų4.50%02%0.022CC..SBendtrans169.9-160.5-177.900000113.2V480 L516 H522V480-G482 PolarHBondContact O-N 2.95Å; G482-L516 PolarHBondContact O-N 3.26Å; G482-L516 VanDerWaalsContact O-N 3.14Å; G482-H522 CarbonylContact C-O 3.57Å; G482-H522 VanDerWaalsContact CA-O 3.25Å; G482-H522 WeakPolarHBondContact CA-O 3.43Å
483E98.9Very high98.4Very high1 Ų15.8 Ų5.81%0.0053%0.026CC..EExtended strand (participates in β ladder)trans-108.288.8-173.4-65.2-179.8-11400110.7H137 H246 L293 L516 Y520 H522 Y523 I524H137-E483 IonicContact CD2-OE2 2.58Å; H137-E483 IonicContact CE1-OE1 3.67Å; H137-E483 IonicContact CE1-OE2 2.69Å; H137-E483 IonicContact NE2-OE1 3.24Å; H137-E483 IonicContact NE2-OE2 3.82Å; H137-E483 PolarHBondContact NE2-OE2 3.37Å; H246-E483 IonicContact CD2-OE2 3.93Å; H246-E483 IonicContact CE1-OE2 3.26Å; H246-E483 PolarHBondContact CE1-OE2 3.15Å; H246-E483 IonicContact NE2-OE2 3.84Å; H246-E483 PolarHBondContact NE2-OE2 2.82Å; L293-E483 HydrophobicContact CD1-CG 4.08Å; E483-L516 HydrophobicContact CG-CD1 4.33Å; E483-L516 HydrophobicContact CG-CD2 4.46Å; E483-L516 HydrophobicContact CG-CG 4.33Å; E483-Y520 HydrophobicContact CG-CE2 4.17Å; E483-Y520 PolarHBondContact OE1-OH 2.98Å; E483-H522 PolarHBondContact N-O 2.89Å; E483-Y523 HydrophobicContact CB-CD1 3.59Å; E483-Y523 HydrophobicContact CB-CE1 3.63Å; E483-Y523 HydrophobicContact CB-CG 4.11Å; E483-Y523 HydrophobicContact CG-CE1 4.22Å; E483-Y523 CarbonylContact O-C 3.58Å; E483-Y523 WeakPolarHBondContact O-CA 3.2Å; E483-Y523 WeakPolarHBondContact OE1-CE2 3.13Å; E483-Y523 PolarHBondContact OE1-OH 2.73Å; E483-Y523 WeakPolarHBondContact OE2-CE1 3.19Å; E483-Y523 PolarHBondContact OE2-OH 2.94Å; E483-I524 PolarHBondContact O-N 2.86Å
484M98.9Very high98.6Very high1 Ų19.2 Ų9.21%0.0054%0.042CC..EExtended strand (participates in β ladder)trans-68.9134171.6-84.5179.3-174.600111N292 L293 G294 V480 L492 I524 L547 Y550N292-M484 CarbonylContact C-O 3.59Å; N292-M484 VanDerWaalsContact CA-O 3.3Å; N292-M484 WeakPolarHBondContact CA-O 3.15Å; N292-M484 HydrophobicContact CB-CB 3.88Å; L293-M484 PolarHBondContact N-O 3.34Å; G294-M484 WeakPolarHBondContact CA-O 3.28Å; G294-M484 PolarHBondContact N-O 3.24Å; V480-M484 HydrophobicContact CG1-CE 3.61Å; V480-M484 HydrophobicContact CG1-CG 3.94Å; V480-M484 HydrophobicContact CG1-SD 3.87Å; V480-M484 HydrophobicContact CG2-CE 3.99Å; V480-M484 HydrophobicContact CG2-SD 3.98Å; M484-L492 HydrophobicContact CE-CD2 3.44Å; M484-L492 VanDerWaalsContact CE-CD2 3.44Å; M484-L492 HydrophobicContact SD-CB 4.26Å; M484-L492 HydrophobicContact SD-CD2 3.53Å; M484-L492 VanDerWaalsContact SD-CD2 3.53Å; M484-I524 WeakPolarHBondContact CA-O 3.28Å; M484-I524 HydrophobicContact CE-CG2 4.15Å; M484-I524 HydrophobicContact CG-CB 3.71Å; M484-I524 HydrophobicContact CG-CD1 4.22Å; M484-I524 HydrophobicContact CG-CG1 4.27Å; M484-I524 HydrophobicContact CG-CG2 4.02Å; M484-L547 HydrophobicContact CE-CD1 4.3Å; M484-Y550 HydrophobicContact CE-CD2 4.25Å; M484-Y550 HydrophobicContact CE-CG 4.31Å
485T98.9Very high98.8Very high2 Ų29 Ų91%0.0124%0.04CC..  trans-63.5168165.858.90000111.7N292 D295 M487 S488 G489 I524 T525 E529 E536N292-T485 PolarHBondContact ND2-O 3.43Å; D295-T485 HydrophobicContact CB-CG2 4.08Å; D295-T485 WeakPolarHBondContact OD1-CA 3.32Å; T485-M487 PolarHBondContact O-N 3.25Å; T485-S488 PolarHBondContact O-N 3.48Å; T485-S488 WeakPolarHBondContact OG1-CB 3.42Å; T485-S488 PolarHBondContact OG1-N 2.76Å; T485-S488 PolarHBondContact OG1-OG 2.78Å; T485-G489 PolarHBondContact O-N 2.93Å; T485-I524 PolarHBondContact N-O 3.01Å; T485-I524 PolarHBondContact OG1-O 2.95Å; T485-T525 HydrophobicContact CG2-CG2 3.78Å; T485-E529 VanDerWaalsContact CB-OE2 3.3Å; T485-E529 WeakPolarHBondContact CB-OE2 3.38Å; T485-E529 PolarHBondContact OG1-OE2 3.35Å; T485-E536 HydrophobicContact CG2-CB 4.19Å; T485-E536 HydrophobicContact CG2-CG 4.38Å
486T98.9Very high98.8Very high0 Ų08.9 Ų8.90%04%0.04CC..Hα-helixtrans-51-54.3178.6-63.60000111.3Y205 N219 N292 D295 V296 G489 R490Y205-T486 HydrophobicContact CE2-CG2 4.27Å; N219-T486 PolarHBondContact O-OG1 2.87Å; N292-T486 WeakPolarHBondContact ND2-CA 3.42Å; N292-T486 PolarHBondContact ND2-O 2.64Å; N292-T486 VanDerWaalsContact ND2-O 3.1Å; D295-T486 WeakPolarHBondContact OD1-CB 3.31Å; D295-T486 PolarHBondContact OD1-N 3.24Å; D295-T486 PolarHBondContact OD1-OG1 3.41Å; V296-T486 WeakPolarHBondContact CG2-OG1 3.38Å; T486-G489 PolarHBondContact O-N 3.12Å; T486-R490 VanDerWaalsContact O-CG 3.31Å; T486-R490 WeakPolarHBondContact O-CG 3.38Å; T486-R490 PolarHBondContact O-N 2.9Å; T486-R490 VanDerWaalsContact O-N 3.1Å
487M98.9Very high98.8Very high0 Ų012.8 Ų12.80%06%0.057CC..Hα-helixtrans-73.3-32.6-177.4-165.559.974.800113Y205 N208 E212 R213 Y216 T485 G489 R490 R491 T526 E529Y205-M487 HydrophobicContact CE2-CB 4.46Å; Y205-M487 HydrophobicContact CE2-CE 3.7Å; N208-M487 HydrophobicContact CB-CG 4.38Å; E212-M487 VanDerWaalsContact CD-SD 3.58Å; E212-M487 HydrophobicContact CG-CE 4.16Å; E212-M487 HydrophobicContact CG-SD 3.92Å; R213-M487 HydrophobicContact CG-CE 4.15Å; Y216-M487 HydrophobicContact CD2-CE 3.93Å; Y216-M487 HydrophobicContact CD2-SD 4.45Å; Y216-M487 HydrophobicContact CE2-CE 3.85Å; Y216-M487 HydrophobicContact CE2-SD 3.81Å; T485-M487 PolarHBondContact O-N 3.25Å; M487-G489 PolarHBondContact O-N 3.21Å; M487-R490 PolarHBondContact O-N 3.25Å; M487-R490 HydrophobicContact SD-CB 4.11Å; M487-R491 HydrophobicContact CG-CG 4.47Å; M487-R491 WeakPolarHBondContact O-CG 3.03Å; M487-R491 PolarHBondContact O-N 3.27Å; M487-T526 HydrophobicContact CB-CG2 3.72Å; M487-T526 HydrophobicContact CG-CG2 3.86Å; M487-E529 WeakPolarHBondContact CB-OE1 3.34Å
488S98.9Very high98.7Very high0 Ų019 Ų190%08%0.084CC..Hα-helixtrans-58.1-48.2172.5-66.10000112.1T485 R491 L492 I524 T525 T526T485-S488 PolarHBondContact O-N 3.48Å; T485-S488 WeakPolarHBondContact OG1-CB 3.42Å; T485-S488 PolarHBondContact OG1-N 2.76Å; T485-S488 PolarHBondContact OG1-OG 2.78Å; S488-R491 PolarHBondContact O-N 2.97Å; S488-L492 WeakPolarHBondContact O-CB 3.47Å; S488-L492 PolarHBondContact O-N 3.48Å; S488-I524 WeakPolarHBondContact CB-O 3.11Å; S488-I524 PolarHBondContact OG-O 3.38Å; S488-T525 WeakPolarHBondContact OG-CA 3.31Å; S488-T526 PolarHBondContact OG-N 3.28Å
489G98.9Very high98.6Very high0 Ų020.5 Ų20.50%09%0.09CC..Hα-helixtrans-64.6-40.3177.800000112.8T485 T486 M487 L492 R493T485-G489 PolarHBondContact O-N 2.93Å; T486-G489 PolarHBondContact O-N 3.12Å; M487-G489 PolarHBondContact O-N 3.21Å; G489-L492 PolarHBondContact O-N 2.81Å; G489-R493 WeakPolarHBondContact O-CG 3.33Å; G489-R493 PolarHBondContact O-N 3.2Å
490R98.9Very high98.5Very high10 Ų1020.5 Ų20.54%0.0389%0.09CC..Hα-helixtrans-57.7-53.1173.6-73.4166.9177.1177.95.4112.2Y205 Y216 S218 T220 D221 T486 M487 L492 R493 E494Y205-R490 PolarHBondContact OH-NH1 3Å; Y216-R490 VanDerWaalsContact CB-NH1 3.31Å; Y216-R490 HydrophobicContact CD1-CG 4.47Å; Y216-R490 HydrophobicContact CE1-CB 4.28Å; Y216-R490 HydrophobicContact CE1-CG 3.89Å; Y216-R490 VanDerWaalsContact CG-NH1 3.28Å; S218-R490 PolarHBondContact O-NH1 2.95Å; S218-R490 PolarHBondContact O-NH2 2.94Å; T220-R490 PolarHBondContact O-NH2 3.05Å; D221-R490 IonicContact OD1-CZ 3.84Å; D221-R490 IonicContact OD1-NE 2.88Å; D221-R490 PolarHBondContact OD1-NE 3.35Å; D221-R490 IonicContact OD1-NH2 3.68Å; D221-R490 PolarHBondContact OD1-NH2 3.14Å; D221-R490 IonicContact OD2-NE 3.9Å; T486-R490 VanDerWaalsContact O-CG 3.31Å; T486-R490 WeakPolarHBondContact O-CG 3.38Å; T486-R490 PolarHBondContact O-N 2.9Å; T486-R490 VanDerWaalsContact O-N 3.1Å; M487-R490 PolarHBondContact O-N 3.25Å; M487-R490 HydrophobicContact SD-CB 4.11Å; R490-L492 VanDerWaalsContact C-N 3.28Å; R490-L492 PolarHBondContact O-N 3.19Å; R490-R493 PolarHBondContact O-N 3.2Å; R490-E494 WeakPolarHBondContact O-CG 3.5Å; R490-E494 PolarHBondContact O-N 3.48Å
491R98.9Very high98.3Very high44 Ų4422.9 Ų22.917%0.16611%0.105CC..Hα-helixtrans-57.9-41.7178.3-72.8179.5176.9-177.42.9111.5E212 M487 S488 A495 E528 L551E212-R491 WeakPolarHBondContact OE1-CG 3.49Å; E212-R491 IonicContact OE1-CZ 3.2Å; E212-R491 IonicContact OE1-NE 3.57Å; E212-R491 PolarHBondContact OE1-NE 2.91Å; E212-R491 IonicContact OE1-NH2 3.96Å; E212-R491 IonicContact OE2-CZ 3.98Å; E212-R491 IonicContact OE2-NE 2.86Å; E212-R491 PolarHBondContact OE2-NE 2.9Å; E212-R491 IonicContact OE2-NH2 3.65Å; E212-R491 PolarHBondContact OE2-NH2 2.87Å; M487-R491 HydrophobicContact CG-CG 4.47Å; M487-R491 WeakPolarHBondContact O-CG 3.03Å; M487-R491 PolarHBondContact O-N 3.27Å; S488-R491 PolarHBondContact O-N 2.97Å; R491-A495 VanDerWaalsContact O-CB 3.28Å; R491-A495 WeakPolarHBondContact O-CB 3.26Å; R491-A495 PolarHBondContact O-N 2.99Å; R491-E528 IonicContact CZ-OE1 3.87Å; R491-E528 IonicContact CZ-OE2 2.93Å; R491-E528 IonicContact NH1-OE1 2.95Å; R491-E528 PolarHBondContact NH1-OE1 3.16Å; R491-E528 IonicContact NH1-OE2 3.75Å; R491-E528 PolarHBondContact NH1-OE2 3.49Å; R491-E528 VanDerWaalsContact NH2-CD 3.34Å; R491-E528 IonicContact NH2-OE1 3.88Å; R491-E528 PolarHBondContact NH2-OE1 2.85Å; R491-E528 IonicContact NH2-OE2 2.94Å; R491-E528 PolarHBondContact NH2-OE2 2.91Å; R491-L551 HydrophobicContact CB-CD2 4.24Å
492L98.9Very high97.9Very high0 Ų026.5 Ų26.50%013%0.13CC..Hα-helixtrans-67.5-46.9178.9-178.461000112.8V478 V480 M484 S488 G489 R490 E494 A495 V496 I513 L551 Y554V478-L492 HydrophobicContact CG1-CD2 3.99Å; V480-L492 HydrophobicContact CG2-CD2 3.77Å; M484-L492 HydrophobicContact CE-CD2 3.44Å; M484-L492 VanDerWaalsContact CE-CD2 3.44Å; M484-L492 HydrophobicContact SD-CB 4.26Å; M484-L492 HydrophobicContact SD-CD2 3.53Å; M484-L492 VanDerWaalsContact SD-CD2 3.53Å; S488-L492 WeakPolarHBondContact O-CB 3.47Å; S488-L492 PolarHBondContact O-N 3.48Å; G489-L492 PolarHBondContact O-N 2.81Å; R490-L492 VanDerWaalsContact C-N 3.28Å; R490-L492 PolarHBondContact O-N 3.19Å; L492-E494 VanDerWaalsContact C-N 3.31Å; L492-E494 PolarHBondContact O-N 2.85Å; L492-A495 PolarHBondContact O-N 3.08Å; L492-V496 HydrophobicContact CD1-CG2 3.96Å; L492-V496 HydrophobicContact CG-CG2 4.46Å; L492-V496 WeakPolarHBondContact O-CG2 3.3Å; L492-V496 PolarHBondContact O-N 2.76Å; L492-I513 HydrophobicContact CB-CD1 4.39Å; L492-I513 HydrophobicContact CD2-CD1 3.78Å; L492-I513 HydrophobicContact CG-CD1 4.05Å; L492-L551 VanDerWaalsContact CA-CD2 3.46Å; L492-L551 HydrophobicContact CB-CD2 3.99Å; L492-L551 HydrophobicContact CD1-CD2 3.97Å; L492-Y554 HydrophobicContact CD1-CD2 3.68Å; L492-Y554 HydrophobicContact CD1-CG 3.87Å; L492-Y554 HydrophobicContact CD2-CD2 3.88Å; L492-Y554 HydrophobicContact CD2-CE2 4.17Å; L492-Y554 HydrophobicContact CD2-CG 4.47Å; L492-Y554 HydrophobicContact CG-CD2 4.45Å
493R98.8Very high97.3Very high37 Ų3728.6 Ų28.614%0.1414%0.143CC..Hα-helixtrans-56.6-46.4175.8-76.1-168.1-67.7-108-3111.4D221 N292 G489 R490 K497 V511 I513D221-R493 VanDerWaalsContact CG-NH2 3.27Å; D221-R493 IonicContact OD1-NH2 3.09Å; D221-R493 IonicContact OD2-CZ 3.64Å; D221-R493 IonicContact OD2-NH1 2.62Å; D221-R493 IonicContact OD2-NH2 3.34Å; D221-R493 PolarHBondContact OD2-NH2 2.9Å; N292-R493 PolarHBondContact OD1-NH1 2.62Å; G489-R493 WeakPolarHBondContact O-CG 3.33Å; G489-R493 PolarHBondContact O-N 3.2Å; R490-R493 PolarHBondContact O-N 3.2Å; R493-K497 WeakPolarHBondContact O-CB 2.82Å; R493-K497 PolarHBondContact O-N 3.2Å; R493-V511 HydrophobicContact CB-CB 4.46Å; R493-V511 HydrophobicContact CB-CG1 4.37Å; R493-V511 WeakPolarHBondContact CD-O 3.42Å; R493-V511 HydrophobicContact CG-CB 4.43Å; R493-V511 HydrophobicContact CG-CG1 4.13Å; R493-I513 HydrophobicContact CG-CD1 3.81Å; R493-I513 HydrophobicContact CG-CG1 3.75Å
494E98.5Very high96.6Very high74 Ų7433.4 Ų33.435%0.34618%0.177SC..Hα-helixtrans-63.6-43.6178.5-70.1-173168.300112.5R215 Y216 R490 L492 K497 K498R215-E494 IonicContact CZ-OE1 3.35Å; R215-E494 IonicContact CZ-OE2 3.89Å; R215-E494 IonicContact NH1-OE1 3.55Å; R215-E494 IonicContact NH1-OE2 2.73Å; R215-E494 PolarHBondContact NH1-OE2 2.82Å; R215-E494 IonicContact NH2-OE1 3.56Å; R215-E494 PolarHBondContact NH2-OE1 2.93Å; R215-E494 IonicContact NH2-OE2 3.91Å; R215-E494 PolarHBondContact NH2-OE2 3.4Å; Y216-E494 PolarHBondContact OH-OE1 3.4Å; R490-E494 WeakPolarHBondContact O-CG 3.5Å; R490-E494 PolarHBondContact O-N 3.48Å; L492-E494 VanDerWaalsContact C-N 3.31Å; L492-E494 PolarHBondContact O-N 2.85Å; E494-K497 PolarHBondContact O-N 3.24Å; E494-K498 WeakPolarHBondContact O-CB 3.38Å; E494-K498 PolarHBondContact O-N 3.32Å
495A98.5Very high95.8Very high11 Ų1137.4 Ų37.49%0.09120%0.202CC..Hα-helixtrans-63.2-45.3179.100000112.4R491 L492 E499 L551 R555R491-A495 VanDerWaalsContact O-CB 3.28Å; R491-A495 WeakPolarHBondContact O-CB 3.26Å; R491-A495 PolarHBondContact O-N 2.99Å; L492-A495 PolarHBondContact O-N 3.08Å; A495-E499 PolarHBondContact O-N 2.92Å; A495-L551 HydrophobicContact CB-CD2 3.92Å; A495-R555 HydrophobicContact CB-CG 4.02Å
496V98.7Very high95.3Very high0 Ų037.6 Ų37.60%020%0.202CC..Hα-helixtrans-67.2-45.7177.2168.50000111I469 V478 L492 K498 E499 L500 V511 A558I469-V496 HydrophobicContact CD1-CG1 4.1Å; I469-V496 HydrophobicContact CD1-CG2 4.26Å; V478-V496 HydrophobicContact CG2-CG1 4.12Å; V478-V496 HydrophobicContact CG2-CG2 4.33Å; L492-V496 HydrophobicContact CD1-CG2 3.96Å; L492-V496 HydrophobicContact CG-CG2 4.46Å; L492-V496 WeakPolarHBondContact O-CG2 3.3Å; L492-V496 PolarHBondContact O-N 2.76Å; V496-K498 VanDerWaalsContact C-N 3.27Å; V496-K498 PolarHBondContact O-N 3.16Å; V496-E499 PolarHBondContact O-N 2.83Å; V496-E499 VanDerWaalsContact O-N 3.16Å; V496-L500 HydrophobicContact CG1-CD1 3.77Å; V496-L500 HydrophobicContact CG1-CG 4.25Å; V496-L500 WeakPolarHBondContact O-CG 3.39Å; V496-L500 PolarHBondContact O-N 3.48Å; V496-V511 HydrophobicContact CB-CG1 4.16Å; V496-V511 HydrophobicContact CG1-CG1 3.88Å; V496-V511 HydrophobicContact CG1-CG2 4.1Å; V496-A558 HydrophobicContact CG1-CB 4.01Å
497K98.3Very high94.7Very high81 Ų8146.6 Ų46.635%0.35224%0.236SC..Hα-helixtrans-58.2-41.6178.4-172164.8-177.11590111.2R493 E494 E499 L500 T501 S509 E510 V511R493-K497 WeakPolarHBondContact O-CB 2.82Å; R493-K497 PolarHBondContact O-N 3.2Å; E494-K497 PolarHBondContact O-N 3.24Å; K497-E499 PolarHBondContact O-N 3.01Å; K497-L500 PolarHBondContact O-N 3.37Å; K497-T501 HydrophobicContact CG-CG2 4.08Å; K497-T501 WeakPolarHBondContact O-CB 3.39Å; K497-T501 WeakPolarHBondContact O-CG2 3.42Å; K497-T501 PolarHBondContact O-N 3.09Å; K497-T501 PolarHBondContact O-OG1 3.35Å; K497-S509 WeakPolarHBondContact CE-O 3.38Å; K497-S509 PolarHBondContact NZ-O 2.95Å; K497-E510 IonicContact NZ-OE2 3.05Å; K497-E510 PolarHBondContact NZ-OE2 3.01Å; K497-V511 HydrophobicContact CB-CG2 3.72Å; K497-V511 HydrophobicContact CG-CG2 4.28Å
498K97.4Very high94.2Very high139 Ų13952.1 Ų52.160%0.60427%0.266SS*.Hα-helixtrans-59.6-43.8176.7-175.2179.3179.2179.90112.7E494 V496 T501E494-K498 WeakPolarHBondContact O-CB 3.38Å; E494-K498 PolarHBondContact O-N 3.32Å; V496-K498 VanDerWaalsContact C-N 3.27Å; V496-K498 PolarHBondContact O-N 3.16Å; K498-T501 PolarHBondContact O-OG1 3.44Å
499E97.6Very high94Very high30 Ų3052.2 Ų52.214%0.1427%0.266CS..Hα-helixtrans-70.5-43.8178.8-63.8-55.9142.900112A495 V496 K497 T501 S502 R555 A558A495-E499 PolarHBondContact O-N 2.92Å; V496-E499 PolarHBondContact O-N 2.83Å; V496-E499 VanDerWaalsContact O-N 3.16Å; K497-E499 PolarHBondContact O-N 3.01Å; E499-T501 PolarHBondContact O-N 2.73Å; E499-S502 WeakPolarHBondContact O-CB 3.41Å; E499-S502 PolarHBondContact O-N 3.32Å; E499-S502 PolarHBondContact O-OG 3.23Å; E499-R555 HydrophobicContact CG-CB 3.91Å; E499-R555 HydrophobicContact CG-CG 3.92Å; E499-R555 IonicContact OE1-CZ 3.91Å; E499-R555 IonicContact OE1-NE 3.57Å; E499-R555 IonicContact OE1-NH1 3.47Å; E499-R555 IonicContact OE1-NH2 2.7Å; E499-R555 PolarHBondContact OE1-NH2 3.42Å; E499-A558 HydrophobicContact CB-CB 3.82Å
500L95.9Very high93.8Very high0 Ų053.7 Ų53.70%027%0.273CS..Hα-helixtrans-60.8-47.5179-71.1175.2000111.8A476 V496 K497 S502 V503 F506 V511 A558 I561A476-L500 HydrophobicContact CB-CD1 3.57Å; V496-L500 HydrophobicContact CG1-CD1 3.77Å; V496-L500 HydrophobicContact CG1-CG 4.25Å; V496-L500 WeakPolarHBondContact O-CG 3.39Å; V496-L500 PolarHBondContact O-N 3.48Å; K497-L500 PolarHBondContact O-N 3.37Å; L500-S502 PolarHBondContact O-N 3.03Å; L500-S502 VanDerWaalsContact O-N 3.09Å; L500-V503 PolarHBondContact O-N 3.36Å; L500-F506 HydrophobicContact CB-CB 4.22Å; L500-F506 VanDerWaalsContact O-CB 3.28Å; L500-F506 WeakPolarHBondContact O-CB 3.1Å; L500-V511 HydrophobicContact CD1-CG2 4.29Å; L500-A558 HydrophobicContact CD2-CB 4.21Å; L500-A558 HydrophobicContact CG-CB 4.14Å; L500-I561 HydrophobicContact CD2-CB 4.36Å; L500-I561 HydrophobicContact CD2-CG2 4.06Å
501T94.4Very high93.8Very high50 Ų5053.3 Ų53.331%0.30727%0.272SS..THydrogen-bonded Turntrans-72.5-0.4-176.257.70000114.3K497 K498 E499 V503 F506 R507K497-T501 HydrophobicContact CG-CG2 4.08Å; K497-T501 WeakPolarHBondContact O-CB 3.39Å; K497-T501 WeakPolarHBondContact O-CG2 3.42Å; K497-T501 PolarHBondContact O-N 3.09Å; K497-T501 PolarHBondContact O-OG1 3.35Å; K498-T501 PolarHBondContact O-OG1 3.44Å; E499-T501 PolarHBondContact O-N 2.73Å; T501-V503 PolarHBondContact O-N 3.11Å; T501-F506 WeakPolarHBondContact CG2-O 3.13Å; T501-R507 WeakPolarHBondContact CG2-O 3.46Å
502S90.3Very high93.8Very high76 Ų7651.5 Ų51.553%0.53127%0.266SS..THydrogen-bonded Turntrans-67.4-18.4173.569.90000113.5E499 L500E499-S502 WeakPolarHBondContact O-CB 3.41Å; E499-S502 PolarHBondContact O-N 3.32Å; E499-S502 PolarHBondContact O-OG 3.23Å; L500-S502 PolarHBondContact O-N 3.03Å; L500-S502 VanDerWaalsContact O-N 3.09Å
503V86.4Confident93.8Very high44 Ų4451.5 Ų51.527%0.26727%0.266SS..SBendtrans-117.5143.3178.4-178.10000109.8L500 T501 T505 F506 A562L500-V503 PolarHBondContact O-N 3.36Å; T501-V503 PolarHBondContact O-N 3.11Å; V503-T505 VanDerWaalsContact C-N 3.26Å; V503-T505 PolarHBondContact O-N 3.32Å; V503-F506 PolarHBondContact O-N 3.3Å; V503-F506 VanDerWaalsContact O-N 3.16Å; V503-A562 HydrophobicContact CG2-CB 4.13Å; V503-A562 WeakPolarHBondContact CG2-O 3.29Å
504S82.8Confident93.8Very high103 Ų10349.8 Ų49.872%0.7226%0.259SS*.G310 helixtrans-57.9-34.4-174.752.80000114F506 R507S504-F506 PolarHBondContact O-N 2.89Å; S504-R507 WeakPolarHBondContact O-CB 3.37Å; S504-R507 PolarHBondContact O-N 3.15Å
505T83.9Confident93.8Very high85 Ų8546.3 Ų46.352%0.52124%0.243SC..G310 helixtrans-55.6-33.5178.9-50.90000112.9P365 V503P365-T505 HydrophobicContact CG-CG2 4Å; V503-T505 VanDerWaalsContact C-N 3.26Å; V503-T505 PolarHBondContact O-N 3.32Å
506F87.9Confident93.8Very high6 Ų645.8 Ų45.83%0.02624%0.239CC..G310 helixtrans-11621-172.8-66.5-67.9000112.4P365 R367 L500 T501 V503 S504 N508 S509 I561 A562P365-F506 HydrophobicContact CG-CZ 4.29Å; R367-F506 HydrophobicContact CG-CZ 4.04Å; L500-F506 HydrophobicContact CB-CB 4.22Å; L500-F506 VanDerWaalsContact O-CB 3.28Å; L500-F506 WeakPolarHBondContact O-CB 3.1Å; T501-F506 WeakPolarHBondContact CG2-O 3.13Å; V503-F506 PolarHBondContact O-N 3.3Å; V503-F506 VanDerWaalsContact O-N 3.16Å; S504-F506 PolarHBondContact O-N 2.89Å; F506-N508 PolarHBondContact O-N 3.37Å; F506-S509 WeakPolarHBondContact CB-OG 3.07Å; F506-S509 VanDerWaalsContact O-CB 3.28Å; F506-S509 WeakPolarHBondContact O-CB 3.21Å; F506-S509 PolarHBondContact O-N 3.02Å; F506-S509 VanDerWaalsContact O-N 3.12Å; F506-S509 PolarHBondContact O-OG 3.33Å; F506-I561 HydrophobicContact CE2-CG2 4.21Å; F506-I561 HydrophobicContact CZ-CG2 4.03Å; F506-A562 HydrophobicContact CD2-CB 4.45Å
507R86.8Confident93.8Very high189 Ų18945.8 Ų45.871%0.71324%0.239SC*.THydrogen-bonded Turntrans-59.2-32.1-174.3-173.2175.1-178.8175.30.6113.8T501 S504T501-R507 WeakPolarHBondContact CG2-O 3.46Å; S504-R507 WeakPolarHBondContact O-CB 3.37Å; S504-R507 PolarHBondContact O-N 3.15Å
508N88.2Confident93.8Very high116 Ų11641.9 Ų41.962%0.6222%0.222SC*.THydrogen-bonded Turntrans-104.525.6-178.5-63.3-18.4000112.4R188 F506 E510R188-N508 PolarHBondContact NH1-O 2.98Å; R188-N508 VanDerWaalsContact NH1-O 3.07Å; R188-N508 PolarHBondContact NH2-O 3.14Å; R188-N508 VanDerWaalsContact NH2-O 3.07Å; F506-N508 PolarHBondContact O-N 3.37Å; N508-E510 PolarHBondContact O-N 3.23Å
509S93.2Very high93.9Very high1 Ų135.3 Ų35.31%0.00719%0.194CC..  trans-64.8130.8-176.4-750000112.7S474 K497 F506S474-S509 CarbonylContact O-C 3.6Å; S474-S509 VanDerWaalsContact O-CA 3.23Å; S474-S509 WeakPolarHBondContact O-CA 3.37Å; K497-S509 WeakPolarHBondContact CE-O 3.38Å; K497-S509 PolarHBondContact NZ-O 2.95Å; F506-S509 WeakPolarHBondContact CB-OG 3.07Å; F506-S509 VanDerWaalsContact O-CB 3.28Å; F506-S509 WeakPolarHBondContact O-CB 3.21Å; F506-S509 PolarHBondContact O-N 3.02Å; F506-S509 VanDerWaalsContact O-N 3.12Å; F506-S509 PolarHBondContact O-OG 3.33Å
510E96.3Very high93.9Very high32 Ų3234.3 Ų34.315%0.1519%0.189CC..EExtended strand (participates in β ladder)trans-101137.3169.2-168.649.2-127.800109R188 R190 L225 S474 V475 A476 K497 N508R188-E510 VanDerWaalsContact NH1-CB 3.29Å; R190-E510 IonicContact CZ-OE1 3.96Å; R190-E510 IonicContact NE-OE1 2.9Å; R190-E510 VanDerWaalsContact NH2-CD 3.33Å; R190-E510 IonicContact NH2-OE1 3.22Å; R190-E510 PolarHBondContact NH2-OE1 2.78Å; L225-E510 HydrophobicContact CD1-CG 3.62Å; S474-E510 PolarHBondContact O-N 3.42Å; V475-E510 CarbonylContact C-O 3.59Å; V475-E510 WeakPolarHBondContact CA-O 3.24Å; A476-E510 PolarHBondContact N-O 2.7Å; K497-E510 IonicContact NZ-OE2 3.05Å; K497-E510 PolarHBondContact NZ-OE2 3.01Å; N508-E510 PolarHBondContact O-N 3.23Å
511V98.4Very high94.1Very high2 Ų234.4 Ų34.41%0.01219%0.189CC..EExtended strand (participates in β ladder)trans-120.2122.3-173.6-175.20000108.9A476 V478 R493 V496 K497 L500A476-V511 HydrophobicContact CB-CG2 4.32Å; A476-V511 WeakPolarHBondContact O-CA 3.38Å; V478-V511 HydrophobicContact CG2-CG1 3.6Å; R493-V511 HydrophobicContact CB-CB 4.46Å; R493-V511 HydrophobicContact CB-CG1 4.37Å; R493-V511 WeakPolarHBondContact CD-O 3.42Å; R493-V511 HydrophobicContact CG-CB 4.43Å; R493-V511 HydrophobicContact CG-CG1 4.13Å; V496-V511 HydrophobicContact CB-CG1 4.16Å; V496-V511 HydrophobicContact CG1-CG1 3.88Å; V496-V511 HydrophobicContact CG1-CG2 4.1Å; K497-V511 HydrophobicContact CB-CG2 3.72Å; K497-V511 HydrophobicContact CG-CG2 4.28Å; L500-V511 HydrophobicContact CD1-CG2 4.29Å
512V98.4Very high94.3Very high5 Ų532.3 Ų32.33%0.0318%0.176CC..EExtended strand (participates in β ladder)trans-112.6147.4172.6-64.80000110.9L225 W242 A476 V477 V478L225-V512 HydrophobicContact CB-CG1 4.08Å; L225-V512 HydrophobicContact CD1-CG1 4.41Å; L225-V512 HydrophobicContact CD2-CG1 3.43Å; L225-V512 VanDerWaalsContact CD2-CG1 3.43Å; L225-V512 HydrophobicContact CG-CG1 4.13Å; W242-V512 HydrophobicContact CD2-CB 4.27Å; W242-V512 HydrophobicContact CD2-CG1 4.48Å; W242-V512 HydrophobicContact CD2-CG2 4.02Å; W242-V512 HydrophobicContact CE3-CG1 4.47Å; W242-V512 HydrophobicContact CE3-CG2 4.35Å; W242-V512 HydrophobicContact CG-CB 4.27Å; W242-V512 HydrophobicContact CG-CG2 4.46Å; W242-V512 HydrophobicContact CH2-CG2 4.45Å; W242-V512 HydrophobicContact CZ2-CG2 4.15Å; A476-V512 PolarHBondContact O-N 3.37Å; V477-V512 HydrophobicContact CB-CG2 4.11Å; V477-V512 HydrophobicContact CG1-CG2 4.17Å; V477-V512 HydrophobicContact CG2-CG2 3.76Å; V478-V512 PolarHBondContact N-O 3.48Å
513I98.8Very high94.7Very high1 Ų129 Ų291%0.00515%0.152CC..EExtended strand (participates in β ladder)trans-92.7129.1169.5-58.9-53.7000106.9W242 S291 N292 V478 V480 L492 R493W242-I513 VanDerWaalsContact CD1-O 3.28Å; S291-I513 WeakPolarHBondContact CA-O 3.49Å; S291-I513 PolarHBondContact OG-O 3.24Å; N292-I513 HydrophobicContact CB-CG2 4.38Å; V478-I513 HydrophobicContact CB-CD1 3.95Å; V478-I513 HydrophobicContact CG1-CD1 4.26Å; V478-I513 HydrophobicContact CG2-CD1 4.44Å; V480-I513 HydrophobicContact CB-CG2 4.14Å; V480-I513 HydrophobicContact CG2-CD1 4.35Å; V480-I513 HydrophobicContact CG2-CG2 3.73Å; L492-I513 HydrophobicContact CB-CD1 4.39Å; L492-I513 HydrophobicContact CD2-CD1 3.78Å; L492-I513 HydrophobicContact CG-CD1 4.05Å; R493-I513 HydrophobicContact CG-CD1 3.81Å; R493-I513 HydrophobicContact CG-CG1 3.75Å
514A98.7Very high95.3Very high0 Ų026.9 Ų26.90%014%0.139CC..EExtended strand (participates in β ladder)trans-104.899.816400000107.3F98 V477 V478 V480 S517F98-A514 HydrophobicContact CE2-CB 3.79Å; F98-A514 HydrophobicContact CZ-CB 4.17Å; V477-A514 HydrophobicContact CG1-CB 3.74Å; V478-A514 PolarHBondContact O-N 2.66Å; V480-A514 PolarHBondContact N-O 3.28Å; A514-S517 PolarHBondContact O-OG 3.05Å
515G98.5Very high96.1Very high1 Ų122.2 Ų22.21%0.0111%0.106CC..  trans-65.9167.7179.300000111.8S134 S290 V480 S517S134-G515 PolarHBondContact OG-O 3.44Å; S290-G515 PolarHBondContact O-N 2.92Å; S290-G515 PolarHBondContact OG-O 3.16Å; S290-G515 VanDerWaalsContact OG-O 3.1Å; V480-G515 CarbonylContact O-C 3.54Å; G515-S517 PolarHBondContact O-N 3.16Å; G515-S517 PolarHBondContact O-OG 3.22Å
516L98.8Very high96.8Very high0 Ų018.1 Ų18.10%08%0.081CC..SBendtrans54.832.9170.1-58.296.8000114.3G104 M105 V106 G135 H137 S290 L293 V480 G482 E483G104-L516 WeakPolarHBondContact O-CD2 3.46Å; M105-L516 HydrophobicContact CB-CD2 4.1Å; M105-L516 HydrophobicContact CG-CD2 3.78Å; V106-L516 PolarHBondContact N-O 3.46Å; G135-L516 PolarHBondContact N-O 3.07Å; H137-L516 HydrophobicContact CB-CD1 4.02Å; H137-L516 HydrophobicContact CB-CD2 3.59Å; H137-L516 HydrophobicContact CB-CG 4.47Å; H137-L516 WeakPolarHBondContact ND1-CD2 3.46Å; S290-L516 WeakPolarHBondContact OG-CD1 3.32Å; L293-L516 HydrophobicContact CD1-CD1 4.21Å; L293-L516 HydrophobicContact CD2-CD1 4.08Å; L293-L516 HydrophobicContact CG-CD1 4.29Å; V480-L516 PolarHBondContact O-N 3.34Å; G482-L516 PolarHBondContact O-N 3.26Å; G482-L516 VanDerWaalsContact O-N 3.14Å; E483-L516 HydrophobicContact CG-CD1 4.33Å; E483-L516 HydrophobicContact CG-CD2 4.46Å; E483-L516 HydrophobicContact CG-CG 4.33Å
517S98.8Very high97.3Very high0 Ų022.6 Ų22.60%010%0.098CC..BIsolated β-bridgetrans-93.8138.5-172.9-63.70000111.7L133 S134 V480 P481 A514 G515 V519L133-S517 CarbonylContact O-C 3.6Å; L133-S517 WeakPolarHBondContact O-CA 3.39Å; S134-S517 WeakPolarHBondContact CB-OG 3.39Å; V480-S517 PolarHBondContact O-N 3.37Å; P481-S517 VanDerWaalsContact CA-O 3.28Å; P481-S517 WeakPolarHBondContact CA-O 3.43Å; A514-S517 PolarHBondContact O-OG 3.05Å; G515-S517 PolarHBondContact O-N 3.16Å; G515-S517 PolarHBondContact O-OG 3.22Å; S517-V519 PolarHBondContact O-N 2.94Å
518N98.8Very high97.9Very high0 Ų015.4 Ų15.40%07%0.073CC..SBendtrans67.7-50.6168.3-59.7-23.8000116.9V106 R111 L133 D466 Q468V106-N518 WeakPolarHBondContact CG1-O 3.28Å; R111-N518 VanDerWaalsContact CB-O 3.31Å; R111-N518 WeakPolarHBondContact CB-O 3.39Å; R111-N518 VanDerWaalsContact CD-CB 3.41Å; R111-N518 VanDerWaalsContact CD-O 3.32Å; R111-N518 WeakPolarHBondContact CD-O 3.3Å; R111-N518 VanDerWaalsContact CZ-CG 3.47Å; R111-N518 PolarHBondContact NH1-OD1 3.25Å; L133-N518 PolarHBondContact N-OD1 2.77Å; L133-N518 VanDerWaalsContact N-OD1 3.14Å; L133-N518 PolarHBondContact O-N 3.09Å; D466-N518 HydrophobicContact CB-CB 3.78Å; Q468-N518 PolarHBondContact OE1-ND2 3.13Å
519V98.7Very high98.4Very high1 Ų110 Ų101%0.0064%0.044CC..SBendtrans-148.8147.8176.152.50000108.4V106 Q108 P462 V465 D466 P481 S517 T521V106-V519 CarbonylContact O-C 3.57Å; V106-V519 WeakPolarHBondContact O-CA 3.24Å; Q108-V519 HydrophobicContact CB-CB 4.05Å; Q108-V519 HydrophobicContact CB-CG2 3.73Å; Q108-V519 HydrophobicContact CG-CG2 4.38Å; P462-V519 HydrophobicContact CB-CG2 4.25Å; P462-V519 HydrophobicContact CG-CG2 4.25Å; V465-V519 HydrophobicContact CB-CG1 4.48Å; V465-V519 HydrophobicContact CG1-CG1 3.85Å; D466-V519 HydrophobicContact CB-CG1 4.24Å; P481-V519 CarbonylContact C-O 3.52Å; P481-V519 WeakPolarHBondContact CA-O 3.5Å; P481-V519 HydrophobicContact CB-CG1 3.69Å; P481-V519 WeakPolarHBondContact CB-O 3.33Å; S517-V519 PolarHBondContact O-N 2.94Å; V519-T521 HydrophobicContact CG2-CG2 4.46Å
520Y98.8Very high98.6Very high9 Ų910 Ų104%0.0354%0.044CC..  trans-102.3124-179.6-178.4-113.9000112.1M105 V106 F146 F151 E483M105-Y520 HydrophobicContact CB-CD1 4.48Å; M105-Y520 HydrophobicContact CB-CD2 3.81Å; M105-Y520 HydrophobicContact CB-CE2 4.48Å; M105-Y520 HydrophobicContact CB-CG 3.79Å; M105-Y520 HydrophobicContact CE-CD1 4.25Å; M105-Y520 HydrophobicContact CE-CE1 3.63Å; M105-Y520 HydrophobicContact CE-CE2 4.05Å; M105-Y520 HydrophobicContact CG-CD1 3.97Å; M105-Y520 HydrophobicContact CG-CD2 3.4Å; M105-Y520 VanDerWaalsContact CG-CD2 3.4Å; M105-Y520 HydrophobicContact CG-CE1 4.14Å; M105-Y520 HydrophobicContact CG-CE2 3.6Å; M105-Y520 HydrophobicContact CG-CG 3.58Å; V106-Y520 PolarHBondContact O-N 2.88Å; F146-Y520 HydrophobicContact CE1-CD1 4.33Å; F151-Y520 AromaticContact CE1-CD1 3.65Å; F151-Y520 HydrophobicContact CE1-CD1 3.65Å; F151-Y520 AromaticContact CE1-CE1 3.66Å; F151-Y520 HydrophobicContact CE1-CE1 3.66Å; F151-Y520 HydrophobicContact CE2-CD1 4.43Å; F151-Y520 AromaticContact CZ-CD1 3.6Å; F151-Y520 HydrophobicContact CZ-CD1 3.6Å; F151-Y520 AromaticContact CZ-CE1 3.96Å; F151-Y520 HydrophobicContact CZ-CE1 3.96Å; E483-Y520 HydrophobicContact CG-CE2 4.17Å; E483-Y520 PolarHBondContact OE1-OH 2.98Å
521T98.8Very high98.8Very high1 Ų110.8 Ų10.81%0.0065%0.048CC..  trans-125.233.3179.775.90000112.7P462 V465 P481 V519 Y542 Y550P462-T521 HydrophobicContact CG-CG2 3.89Å; V465-T521 HydrophobicContact CG1-CG2 3.93Å; V465-T521 HydrophobicContact CG2-CG2 3.74Å; P481-T521 HydrophobicContact CB-CG2 4.43Å; P481-T521 PolarHBondContact O-N 2.84Å; P481-T521 PolarHBondContact O-OG1 2.73Å; V519-T521 HydrophobicContact CG2-CG2 4.46Å; T521-Y542 HydrophobicContact CG2-CE2 4.1Å; T521-Y550 PolarHBondContact OG1-OH 2.86Å
522H98.7Very high98.7Very high7 Ų711.7 Ų11.73%0.0325%0.053CC..BIsolated β-bridgetrans58.8-136.6-175.7-67.1-102.2000112.9F151 F399 H461 G482 E483 S539 I541F151-H522 AromaticContact CE1-CE1 3.89Å; F151-H522 AromaticContact CE1-NE2 3.28Å; F151-H522 VanDerWaalsContact CE1-NE2 3.28Å; F151-H522 WeakPolarHBondContact CE1-NE2 3.4Å; F151-H522 AromaticContact CZ-CD2 3.72Å; F151-H522 AromaticContact CZ-NE2 3.31Å; F151-H522 VanDerWaalsContact CZ-NE2 3.31Å; F151-H522 WeakPolarHBondContact CZ-NE2 3.4Å; F399-H522 AromaticContact CE2-CE1 3.85Å; H461-H522 AromaticContact CE1-CD2 3.69Å; H461-H522 AromaticContact CE1-NE2 3.55Å; H461-H522 AromaticContact NE2-CD2 3.25Å; H461-H522 PolarHBondContact NE2-CD2 2.83Å; H461-H522 AromaticContact NE2-NE2 2.94Å; H461-H522 PolarHBondContact NE2-NE2 2.93Å; G482-H522 CarbonylContact C-O 3.57Å; G482-H522 VanDerWaalsContact CA-O 3.25Å; G482-H522 WeakPolarHBondContact CA-O 3.43Å; E483-H522 PolarHBondContact N-O 2.89Å; H522-S539 WeakPolarHBondContact CB-O 3.46Å; H522-I541 HydrophobicContact CB-CG2 4.07Å
523Y98.9Very high98.7Very high6 Ų611.4 Ų11.42%0.0245%0.051CC..EExtended strand (participates in β ladder)trans-97.4158.1-166.7-72-95.2000111.8R200 G294 E483 Y535 E536 S539 T540R200-Y523 VanDerWaalsContact NH2-CZ 3.34Å; R200-Y523 PolarHBondContact NH2-OH 3.11Å; G294-Y523 WeakPolarHBondContact O-CE1 3.45Å; E483-Y523 HydrophobicContact CB-CD1 3.59Å; E483-Y523 HydrophobicContact CB-CE1 3.63Å; E483-Y523 HydrophobicContact CB-CG 4.11Å; E483-Y523 HydrophobicContact CG-CE1 4.22Å; E483-Y523 CarbonylContact O-C 3.58Å; E483-Y523 WeakPolarHBondContact O-CA 3.2Å; E483-Y523 WeakPolarHBondContact OE1-CE2 3.13Å; E483-Y523 PolarHBondContact OE1-OH 2.73Å; E483-Y523 WeakPolarHBondContact OE2-CE1 3.19Å; E483-Y523 PolarHBondContact OE2-OH 2.94Å; Y523-Y535 HydrophobicContact CD2-CE1 4.09Å; Y523-Y535 HydrophobicContact CE1-CE1 4.49Å; Y523-Y535 HydrophobicContact CE2-CD1 4.06Å; Y523-Y535 AromaticContact CE2-CE1 3.29Å; Y523-Y535 HydrophobicContact CE2-CE1 3.29Å; Y523-Y535 AromaticContact CZ-CE1 3.54Å; Y523-E536 WeakPolarHBondContact CB-O 3Å; Y523-E536 HydrophobicContact CD1-CB 3.86Å; Y523-E536 HydrophobicContact CD1-CG 3.55Å; Y523-E536 HydrophobicContact CE1-CG 3.87Å; Y523-E536 HydrophobicContact CG-CB 4.14Å; Y523-E536 HydrophobicContact CG-CG 4.26Å; Y523-S539 PolarHBondContact N-O 2.87Å; Y523-S539 VanDerWaalsContact N-O 3.17Å; Y523-T540 WeakPolarHBondContact O-CA 3.46Å; Y523-T540 PolarHBondContact O-OG1 2.69Å
524I98.9Very high98.7Very high0 Ų011.5 Ų11.50%05%0.051CC..EExtended strand (participates in β ladder)trans-133104.8172.6-55.687.8000107.5V480 E483 M484 T485 S488 T546 L547 Y550V480-I524 HydrophobicContact CG1-CD1 4.35Å; E483-I524 PolarHBondContact O-N 2.86Å; M484-I524 WeakPolarHBondContact CA-O 3.28Å; M484-I524 HydrophobicContact CE-CG2 4.15Å; M484-I524 HydrophobicContact CG-CB 3.71Å; M484-I524 HydrophobicContact CG-CD1 4.22Å; M484-I524 HydrophobicContact CG-CG1 4.27Å; M484-I524 HydrophobicContact CG-CG2 4.02Å; T485-I524 PolarHBondContact N-O 3.01Å; T485-I524 PolarHBondContact OG1-O 2.95Å; S488-I524 WeakPolarHBondContact CB-O 3.11Å; S488-I524 PolarHBondContact OG-O 3.38Å; I524-T546 HydrophobicContact CG1-CG2 4.23Å; I524-T546 HydrophobicContact CG2-CG2 4.25Å; I524-L547 HydrophobicContact CG2-CB 3.95Å; I524-L547 HydrophobicContact CG2-CD1 4.07Å; I524-Y550 HydrophobicContact CD1-CE2 4.39Å; I524-Y550 HydrophobicContact CG1-CD2 3.99Å; I524-Y550 HydrophobicContact CG1-CE2 3.62Å; I524-Y550 HydrophobicContact CG2-CD2 4.06Å; I524-Y550 HydrophobicContact CG2-CE2 4.48Å
525T98.9Very high98.7Very high4 Ų413.1 Ų13.13%0.0256%0.058CC..  trans-94.3163.3172.261.30000111.8T485 S488 E529 Y530 E536 T540 L547T485-T525 HydrophobicContact CG2-CG2 3.78Å; S488-T525 WeakPolarHBondContact OG-CA 3.31Å; T525-E529 HydrophobicContact CG2-CB 4.26Å; T525-Y530 WeakPolarHBondContact OG1-CB 3.21Å; T525-E536 VanDerWaalsContact CG2-C 3.43Å; T525-E536 HydrophobicContact CG2-CB 3.62Å; T525-T540 PolarHBondContact N-OG1 3.16Å; T525-T540 PolarHBondContact OG1-OG1 2.88Å; T525-L547 WeakPolarHBondContact O-CB 3.13Å
526T98.9Very high98.7Very high0 Ų013.2 Ų13.20%06%0.058CC..  trans-64.3165.316369.60000110.4N208 M487 S488 E528 E529 Y530 L547N208-T526 WeakPolarHBondContact OD1-CB 3.23Å; N208-T526 WeakPolarHBondContact OD1-CG2 3.41Å; N208-T526 PolarHBondContact OD1-OG1 2.88Å; M487-T526 HydrophobicContact CB-CG2 3.72Å; M487-T526 HydrophobicContact CG-CG2 3.86Å; S488-T526 PolarHBondContact OG-N 3.28Å; T526-E528 WeakPolarHBondContact CB-OE2 3.38Å; T526-E528 PolarHBondContact O-N 3.04Å; T526-E528 PolarHBondContact OG1-N 3.34Å; T526-E528 PolarHBondContact OG1-OE2 3.36Å; T526-E529 PolarHBondContact N-OE2 3.36Å; T526-E529 PolarHBondContact O-N 2.93Å; T526-E529 WeakPolarHBondContact OG1-CB 3.39Å; T526-E529 VanDerWaalsContact OG1-CG 3.26Å; T526-E529 WeakPolarHBondContact OG1-CG 3.26Å; T526-E529 PolarHBondContact OG1-N 2.64Å; T526-Y530 VanDerWaalsContact O-CB 3.31Å; T526-Y530 WeakPolarHBondContact O-CB 3.3Å; T526-Y530 PolarHBondContact O-N 3.3Å; T526-L547 HydrophobicContact CG2-CD2 3.86Å
527Y98.8Very high98.7Very high100 Ų10013.3 Ų13.339%0.3926%0.059SC..Hα-helixtrans-58.2-39.8173.7177.7-88.8000110.4Y530 Q531 P544 H545Y527-Y530 WeakPolarHBondContact O-CB 3.41Å; Y527-Y530 PolarHBondContact O-N 3.28Å; Y527-Q531 HydrophobicContact CD1-CG 4.41Å; Y527-Q531 HydrophobicContact CE1-CG 4.12Å; Y527-Q531 VanDerWaalsContact O-CG 3.3Å; Y527-Q531 WeakPolarHBondContact O-CG 3.3Å; Y527-Q531 PolarHBondContact O-N 2.95Å; Y527-Q531 PolarHBondContact O-NE2 3Å; Y527-P544 HydrophobicContact CD2-CB 3.75Å; Y527-P544 HydrophobicContact CE2-CB 3.73Å; Y527-P544 HydrophobicContact CE2-CG 4.42Å; Y527-H545 AromaticContact CD2-CE1 3.47Å; Y527-H545 VanDerWaalsContact CD2-CE1 3.47Å; Y527-H545 WeakPolarHBondContact CD2-CE1 3.33Å; Y527-H545 AromaticContact CD2-ND1 3.72Å; Y527-H545 AromaticContact CE2-CE1 3.37Å; Y527-H545 WeakPolarHBondContact CE2-CE1 3.4Å; Y527-H545 AromaticContact CE2-NE2 3.87Å
528E98.8Very high98.7Very high38 Ų3813.3 Ų13.318%0.1786%0.059CC..Hα-helixtrans-69.1-49.1-178.5-58.390.6150.100111.5N207 P209 R491 T526 Y530 Q531N207-E528 PolarHBondContact ND2-O 2.9Å; N207-E528 WeakPolarHBondContact O-CB 3.4Å; P209-E528 WeakPolarHBondContact CD-OE1 3.48Å; R491-E528 IonicContact CZ-OE1 3.87Å; R491-E528 IonicContact CZ-OE2 2.93Å; R491-E528 IonicContact NH1-OE1 2.95Å; R491-E528 PolarHBondContact NH1-OE1 3.16Å; R491-E528 IonicContact NH1-OE2 3.75Å; R491-E528 PolarHBondContact NH1-OE2 3.49Å; R491-E528 VanDerWaalsContact NH2-CD 3.34Å; R491-E528 IonicContact NH2-OE1 3.88Å; R491-E528 PolarHBondContact NH2-OE1 2.85Å; R491-E528 IonicContact NH2-OE2 2.94Å; R491-E528 PolarHBondContact NH2-OE2 2.91Å; T526-E528 WeakPolarHBondContact CB-OE2 3.38Å; T526-E528 PolarHBondContact O-N 3.04Å; T526-E528 PolarHBondContact OG1-N 3.34Å; T526-E528 PolarHBondContact OG1-OE2 3.36Å; E528-Y530 PolarHBondContact O-N 3.28Å; E528-Q531 WeakPolarHBondContact O-CB 3.29Å; E528-Q531 PolarHBondContact O-N 2.79Å; E528-Q531 VanDerWaalsContact O-N 3.15Å
529E98.9Very high98.7Very high2 Ų213.3 Ų13.31%0.0096%0.059CC..Hα-helixtrans-60-36.6174.3-74.9161.2-170.800111.8S204 N208 T485 M487 T525 T526 Q531 V532S204-E529 WeakPolarHBondContact O-CG 3.45Å; N208-E529 PolarHBondContact ND2-OE1 3.11Å; T485-E529 VanDerWaalsContact CB-OE2 3.3Å; T485-E529 WeakPolarHBondContact CB-OE2 3.38Å; T485-E529 PolarHBondContact OG1-OE2 3.35Å; M487-E529 WeakPolarHBondContact CB-OE1 3.34Å; T525-E529 HydrophobicContact CG2-CB 4.26Å; T526-E529 PolarHBondContact N-OE2 3.36Å; T526-E529 PolarHBondContact O-N 2.93Å; T526-E529 WeakPolarHBondContact OG1-CB 3.39Å; T526-E529 VanDerWaalsContact OG1-CG 3.26Å; T526-E529 WeakPolarHBondContact OG1-CG 3.26Å; T526-E529 PolarHBondContact OG1-N 2.64Å; E529-Q531 VanDerWaalsContact C-N 3.27Å; E529-Q531 PolarHBondContact O-N 3.08Å; E529-V532 PolarHBondContact O-N 3.21Å
530Y98.9Very high98.7Very high0 Ų013.3 Ų13.30%06%0.059CC..Hα-helixtrans-59.2-37.8176.3-174.4-87.1000111.8H442 K445 T525 T526 Y527 E528 V532 Q533 G537 T540 P544H442-Y530 PolarHBondContact ND1-OH 3.14Å; H442-Y530 VanDerWaalsContact ND1-OH 3.11Å; H442-Y530 WeakPolarHBondContact O-CE1 3.39Å; H442-Y530 PolarHBondContact O-OH 3.02Å; K445-Y530 HydrophobicContact CB-CE1 4.32Å; K445-Y530 VanDerWaalsContact CB-OH 3.3Å; K445-Y530 WeakPolarHBondContact CB-OH 3.44Å; K445-Y530 VanDerWaalsContact CE-OH 3.23Å; K445-Y530 WeakPolarHBondContact CE-OH 3.28Å; T525-Y530 WeakPolarHBondContact OG1-CB 3.21Å; T526-Y530 VanDerWaalsContact O-CB 3.31Å; T526-Y530 WeakPolarHBondContact O-CB 3.3Å; T526-Y530 PolarHBondContact O-N 3.3Å; Y527-Y530 WeakPolarHBondContact O-CB 3.41Å; Y527-Y530 PolarHBondContact O-N 3.28Å; E528-Y530 PolarHBondContact O-N 3.28Å; Y530-V532 PolarHBondContact O-N 2.91Å; Y530-V532 VanDerWaalsContact O-N 3.11Å; Y530-Q533 WeakPolarHBondContact O-CG 3.4Å; Y530-Q533 PolarHBondContact O-N 2.73Å; Y530-Q533 VanDerWaalsContact O-N 3.09Å; Y530-Q533 PolarHBondContact O-NE2 2.89Å; Y530-G537 WeakPolarHBondContact CD2-O 3.45Å; Y530-G537 WeakPolarHBondContact CE2-O 3.32Å; Y530-T540 HydrophobicContact CD2-CG2 3.96Å; Y530-T540 HydrophobicContact CE2-CG2 4.2Å; Y530-P544 HydrophobicContact CD1-CB 3.56Å; Y530-P544 HydrophobicContact CD1-CG 4.5Å; Y530-P544 HydrophobicContact CE1-CB 3.65Å; Y530-P544 HydrophobicContact CE1-CG 4.12Å; Y530-P544 HydrophobicContact CG-CB 4.06Å
531Q98.6Very high98.7Very high50 Ų5012.9 Ų12.923%0.2346%0.057CC..Hα-helixtrans-61.9-24.5-177.7-54.9-46.3-64.200113Y527 E528 E529Y527-Q531 HydrophobicContact CD1-CG 4.41Å; Y527-Q531 HydrophobicContact CE1-CG 4.12Å; Y527-Q531 VanDerWaalsContact O-CG 3.3Å; Y527-Q531 WeakPolarHBondContact O-CG 3.3Å; Y527-Q531 PolarHBondContact O-N 2.95Å; Y527-Q531 PolarHBondContact O-NE2 3Å; E528-Q531 WeakPolarHBondContact O-CB 3.29Å; E528-Q531 PolarHBondContact O-N 2.79Å; E528-Q531 VanDerWaalsContact O-N 3.15Å; E529-Q531 VanDerWaalsContact C-N 3.27Å; E529-Q531 PolarHBondContact O-N 3.08Å
532V98.1Very high98.7Very high20 Ų2012.9 Ų12.912%0.1216%0.057CC..Hα-helixtrans-78.6-24.4-178.9-172.60000111.7H203 N207 G415 E529 Y530 R534H203-V532 WeakPolarHBondContact ND1-CG1 3.33Å; N207-V532 HydrophobicContact CB-CG2 3.91Å; G415-V532 VanDerWaalsContact CA-O 3.31Å; G415-V532 WeakPolarHBondContact CA-O 3.38Å; E529-V532 PolarHBondContact O-N 3.21Å; Y530-V532 PolarHBondContact O-N 2.91Å; Y530-V532 VanDerWaalsContact O-N 3.11Å; V532-R534 VanDerWaalsContact C-N 3.28Å; V532-R534 HydrophobicContact CG1-CG 4.07Å; V532-R534 PolarHBondContact O-N 2.87Å
533Q98.2Very high98.7Very high0 Ų012.6 Ų12.60%06%0.056CC..  trans52.739.4-179.9-69.7-62.8-60.500114.8S398 G415 A416 V417 P444 K445 Y530 G537 A538S398-Q533 WeakPolarHBondContact CB-O 3.48Å; S398-Q533 PolarHBondContact OG-O 3.33Å; S398-Q533 VanDerWaalsContact OG-O 3.07Å; G415-Q533 VanDerWaalsContact CA-O 3.25Å; G415-Q533 WeakPolarHBondContact CA-O 3.32Å; G415-Q533 PolarHBondContact N-O 2.8Å; A416-Q533 PolarHBondContact N-O 2.96Å; A416-Q533 WeakPolarHBondContact O-CB 3.2Å; V417-Q533 HydrophobicContact CG1-CB 4.11Å; V417-Q533 HydrophobicContact CG1-CG 4.21Å; P444-Q533 HydrophobicContact CG-CG 4.49Å; K445-Q533 HydrophobicContact CB-CG 4.49Å; K445-Q533 VanDerWaalsContact CB-OE1 3.29Å; K445-Q533 VanDerWaalsContact CG-OE1 3.26Å; Y530-Q533 WeakPolarHBondContact O-CG 3.4Å; Y530-Q533 PolarHBondContact O-N 2.73Å; Y530-Q533 VanDerWaalsContact O-N 3.09Å; Y530-Q533 PolarHBondContact O-NE2 2.89Å; Q533-G537 PolarHBondContact NE2-O 3.35Å; Q533-A538 VanDerWaalsContact OE1-CA 3.28Å
534R98.2Very high98.7Very high2 Ų212.7 Ų12.71%0.0086%0.057CC..  trans-66.2179.6157.8-72.5-172.159.390.6-3.7110.9R200 S201 S204 L315 S317 Q414 V532 E536 G537 A538R200-R534 PolarHBondContact O-NH2 3.27Å; S201-R534 PolarHBondContact OG-NE 2.79Å; S204-R534 WeakPolarHBondContact OG-CD 3.46Å; L315-R534 PolarHBondContact O-NH1 2.82Å; S317-R534 PolarHBondContact OG-NH1 3.18Å; S317-R534 PolarHBondContact OG-NH2 2.89Å; Q414-R534 HydrophobicContact CB-CB 4.4Å; Q414-R534 HydrophobicContact CB-CG 4.21Å; Q414-R534 VanDerWaalsContact OE1-CZ 3.24Å; V532-R534 VanDerWaalsContact C-N 3.28Å; V532-R534 HydrophobicContact CG1-CG 4.07Å; V532-R534 PolarHBondContact O-N 2.87Å; R534-E536 VanDerWaalsContact C-N 3.27Å; R534-E536 PolarHBondContact O-N 2.98Å; R534-G537 PolarHBondContact O-N 3.04Å; R534-A538 PolarHBondContact O-N 3.37Å
535Y98.3Very high98.7Very high34 Ų3414.5 Ų14.513%0.1337%0.066CC..Hα-helixtrans-50.1-46.1-175178.3-98.8000113.1S398 F399 G402 T403 Y523 G537 A538 S539S398-Y535 WeakPolarHBondContact O-CD2 3.47Å; F399-Y535 HydrophobicContact CD2-CE2 4.13Å; F399-Y535 VanDerWaalsContact O-CE2 3.25Å; F399-Y535 WeakPolarHBondContact O-CE2 3.45Å; G402-Y535 WeakPolarHBondContact O-CD2 3.44Å; T403-Y535 HydrophobicContact CG2-CD1 3.29Å; T403-Y535 HydrophobicContact CG2-CD2 4.13Å; T403-Y535 HydrophobicContact CG2-CE1 3.83Å; T403-Y535 HydrophobicContact CG2-CG 3.46Å; T403-Y535 VanDerWaalsContact CG2-CG 3.46Å; Y523-Y535 HydrophobicContact CD2-CE1 4.09Å; Y523-Y535 HydrophobicContact CE1-CE1 4.49Å; Y523-Y535 HydrophobicContact CE2-CD1 4.06Å; Y523-Y535 AromaticContact CE2-CE1 3.29Å; Y523-Y535 HydrophobicContact CE2-CE1 3.29Å; Y523-Y535 AromaticContact CZ-CE1 3.54Å; Y535-G537 PolarHBondContact O-N 2.86Å; Y535-A538 PolarHBondContact O-N 3.01Å; Y535-S539 WeakPolarHBondContact O-CB 3.3Å; Y535-S539 PolarHBondContact O-N 2.89Å; Y535-S539 PolarHBondContact O-OG 3.46Å
536E98.8Very high98.7Very high3 Ų314.3 Ų14.31%0.0147%0.065CC..Hα-helixtrans-66.4-38.4-179.4-58.180.6-174.100112.1R200 S201 G294 T485 Y523 T525 R534 S539 T540R200-E536 IonicContact CZ-OE1 3.6Å; R200-E536 IonicContact NE-OE1 2.72Å; R200-E536 PolarHBondContact NE-OE1 2.94Å; R200-E536 IonicContact NH2-OE1 3.94Å; S201-E536 WeakPolarHBondContact CB-OE2 3.23Å; S201-E536 VanDerWaalsContact OG-CD 3.31Å; S201-E536 PolarHBondContact OG-OE1 3.46Å; S201-E536 PolarHBondContact OG-OE2 3.2Å; G294-E536 VanDerWaalsContact O-CG 3.28Å; G294-E536 WeakPolarHBondContact O-CG 3.43Å; T485-E536 HydrophobicContact CG2-CB 4.19Å; T485-E536 HydrophobicContact CG2-CG 4.38Å; Y523-E536 WeakPolarHBondContact CB-O 3Å; Y523-E536 HydrophobicContact CD1-CB 3.86Å; Y523-E536 HydrophobicContact CD1-CG 3.55Å; Y523-E536 HydrophobicContact CE1-CG 3.87Å; Y523-E536 HydrophobicContact CG-CB 4.14Å; Y523-E536 HydrophobicContact CG-CG 4.26Å; T525-E536 VanDerWaalsContact CG2-C 3.43Å; T525-E536 HydrophobicContact CG2-CB 3.62Å; R534-E536 VanDerWaalsContact C-N 3.27Å; R534-E536 PolarHBondContact O-N 2.98Å; E536-S539 CarbonylContact O-C 3.41Å; E536-S539 PolarHBondContact O-N 3.48Å; E536-T540 PolarHBondContact O-N 2.65Å; E536-T540 PolarHBondContact O-OG1 3.47Å
537G98.6Very high98.6Very high2 Ų214.5 Ų14.52%0.0217%0.065CC..Hα-helixtrans-69.8-41.9177.500000112.3K445 Y530 Q533 R534 Y535 S539 T540K445-G537 WeakPolarHBondContact CE-O 3.21Å; Y530-G537 WeakPolarHBondContact CD2-O 3.45Å; Y530-G537 WeakPolarHBondContact CE2-O 3.32Å; Q533-G537 PolarHBondContact NE2-O 3.35Å; R534-G537 PolarHBondContact O-N 3.04Å; Y535-G537 PolarHBondContact O-N 2.86Å; G537-S539 PolarHBondContact O-N 2.82Å; G537-T540 PolarHBondContact O-N 3.46Å
538A98.6Very high98.6Very high0 Ų011.1 Ų11.10%06%0.056CC..Hα-helixtrans-64.5-30.3173.300000112.1G396 K445 Q533 R534 Y535G396-A538 PolarHBondContact N-O 2.86Å; K445-A538 VanDerWaalsContact CE-O 3.31Å; K445-A538 WeakPolarHBondContact CE-O 3.38Å; K445-A538 PolarHBondContact NZ-O 2.86Å; Q533-A538 VanDerWaalsContact OE1-CA 3.28Å; R534-A538 PolarHBondContact O-N 3.37Å; Y535-A538 PolarHBondContact O-N 3.01Å
539S98.7Very high98.6Very high0 Ų09.4 Ų9.40%05%0.047CC..THydrogen-bonded Turntrans-92.75.3178.7-52.30000114.1H522 Y523 Y535 E536 G537 I541H522-S539 WeakPolarHBondContact CB-O 3.46Å; Y523-S539 PolarHBondContact N-O 2.87Å; Y523-S539 VanDerWaalsContact N-O 3.17Å; Y535-S539 WeakPolarHBondContact O-CB 3.3Å; Y535-S539 PolarHBondContact O-N 2.89Å; Y535-S539 PolarHBondContact O-OG 3.46Å; E536-S539 CarbonylContact O-C 3.41Å; E536-S539 PolarHBondContact O-N 3.48Å; G537-S539 PolarHBondContact O-N 2.82Å; S539-I541 WeakPolarHBondContact O-CG2 3.43Å; S539-I541 PolarHBondContact O-N 3.28Å; S539-I541 VanDerWaalsContact O-N 3.16Å
540T98.9Very high98.6Very high1 Ų19.3 Ų9.31%0.0065%0.047CC..BIsolated β-bridgetrans-82.190171.6-65.50000109.5K445 Y523 T525 Y530 E536 G537 Y542 G543 T546K445-T540 PolarHBondContact NZ-O 3.4Å; Y523-T540 WeakPolarHBondContact O-CA 3.46Å; Y523-T540 PolarHBondContact O-OG1 2.69Å; T525-T540 PolarHBondContact N-OG1 3.16Å; T525-T540 PolarHBondContact OG1-OG1 2.88Å; Y530-T540 HydrophobicContact CD2-CG2 3.96Å; Y530-T540 HydrophobicContact CE2-CG2 4.2Å; E536-T540 PolarHBondContact O-N 2.65Å; E536-T540 PolarHBondContact O-OG1 3.47Å; G537-T540 PolarHBondContact O-N 3.46Å; T540-Y542 PolarHBondContact O-N 2.9Å; T540-G543 PolarHBondContact O-N 2.85Å; T540-T546 HydrophobicContact CG2-CG2 4.08Å; T540-T546 WeakPolarHBondContact CG2-OG1 3.42Å
541I98.8Very high98.6Very high1 Ų110.9 Ų10.91%0.0056%0.055CC..THydrogen-bonded Turntrans-72.5-25.5-157.163.8177.2000114.9P393 A394 L395 H442 H461 H522 S539 G543P393-I541 CarbonylContact C-O 3.54Å; P393-I541 WeakPolarHBondContact CA-O 3.06Å; P393-I541 HydrophobicContact CB-CB 4.05Å; P393-I541 HydrophobicContact CB-CD1 3.96Å; P393-I541 HydrophobicContact CB-CG1 4.16Å; A394-I541 PolarHBondContact N-O 2.94Å; L395-I541 HydrophobicContact CD2-CG2 3.69Å; L395-I541 HydrophobicContact CG-CG2 4.34Å; H442-I541 PolarHBondContact CE1-O 3.01Å; H442-I541 PolarHBondContact NE2-O 3.4Å; H461-I541 HydrophobicContact CB-CD1 4.49Å; H522-I541 HydrophobicContact CB-CG2 4.07Å; S539-I541 WeakPolarHBondContact O-CG2 3.43Å; S539-I541 PolarHBondContact O-N 3.28Å; S539-I541 VanDerWaalsContact O-N 3.16Å; I541-G543 VanDerWaalsContact C-N 3.32Å; I541-G543 PolarHBondContact O-N 2.9Å
542Y98.9Very high98.6Very high1 Ų111.2 Ų11.20%0.0046%0.057CC..THydrogen-bonded Turntrans-94.618.5-178.1-52.3-68000113.7M375 C391 P393 P462 V465 T521 T540 T546M375-Y542 HydrophobicContact CB-CD1 3.91Å; M375-Y542 HydrophobicContact CB-CD2 3.91Å; M375-Y542 HydrophobicContact CB-CE1 3.77Å; M375-Y542 HydrophobicContact CB-CE2 3.75Å; M375-Y542 HydrophobicContact CB-CG 3.98Å; M375-Y542 HydrophobicContact CE-CD2 3.93Å; M375-Y542 HydrophobicContact CE-CE2 4.47Å; M375-Y542 HydrophobicContact CE-CG 4.43Å; M375-Y542 HydrophobicContact CG-CD2 4.45Å; M375-Y542 HydrophobicContact CG-CE2 4.19Å; C391-Y542 PolarHBondContact N-O 3.2Å; P393-Y542 HydrophobicContact CB-CD1 4.24Å; P393-Y542 HydrophobicContact CB-CE1 3.97Å; P393-Y542 HydrophobicContact CG-CE1 4.25Å; P462-Y542 PolarHBondContact O-OH 3.04Å; V465-Y542 HydrophobicContact CG2-CE2 4.23Å; V465-Y542 VanDerWaalsContact CG2-OH 3.26Å; V465-Y542 WeakPolarHBondContact CG2-OH 3.33Å; T521-Y542 HydrophobicContact CG2-CE2 4.1Å; T540-Y542 PolarHBondContact O-N 2.9Å; Y542-T546 WeakPolarHBondContact CA-OG1 3.41Å; Y542-T546 WeakPolarHBondContact CB-OG1 3.38Å; Y542-T546 HydrophobicContact CD2-CG2 4.11Å; Y542-T546 PolarHBondContact N-OG1 3.24Å
543G98.7Very high98.7Very high0 Ų012 Ų120%06%0.059CC..  trans90.3-175.1174.500000114.4H442 T540 I541 H545 T546H442-G543 PolarHBondContact CE1-N 2.79Å; H442-G543 VanDerWaalsContact CE1-N 3.34Å; T540-G543 PolarHBondContact O-N 2.85Å; I541-G543 VanDerWaalsContact C-N 3.32Å; I541-G543 PolarHBondContact O-N 2.9Å; G543-H545 PolarHBondContact O-N 2.91Å; G543-H545 VanDerWaalsContact O-N 3.13Å; G543-T546 PolarHBondContact N-OG1 3.41Å; G543-T546 WeakPolarHBondContact O-CB 3.45Å; G543-T546 PolarHBondContact O-N 2.81Å; G543-T546 VanDerWaalsContact O-N 3.14Å; G543-T546 PolarHBondContact O-OG1 3.41Å
544P98.7Very high98.7Very high8 Ų812 Ų125%0.0526%0.059CC..THydrogen-bonded Turntrans-63.3-22.1-172.123.9-33.3000113.8C441 Y527 Y530C441-P544 VanDerWaalsContact O-CD 3.29Å; C441-P544 WeakPolarHBondContact O-CD 3.29Å; Y527-P544 HydrophobicContact CD2-CB 3.75Å; Y527-P544 HydrophobicContact CE2-CB 3.73Å; Y527-P544 HydrophobicContact CE2-CG 4.42Å; Y530-P544 HydrophobicContact CD1-CB 3.56Å; Y530-P544 HydrophobicContact CD1-CG 4.5Å; Y530-P544 HydrophobicContact CE1-CB 3.65Å; Y530-P544 HydrophobicContact CE1-CG 4.12Å; Y530-P544 HydrophobicContact CG-CB 4.06Å
545H98.6Very high98.7Very high38 Ų3816 Ų1618%0.1767%0.074CC..THydrogen-bonded Turntrans-99.716.2-178.8-59.3-60.2000113.7V388 Y527 G543 L547 T548 A549V388-H545 HydrophobicContact CB-CB 4.4Å; V388-H545 HydrophobicContact CG2-CB 4.12Å; Y527-H545 AromaticContact CD2-CE1 3.47Å; Y527-H545 VanDerWaalsContact CD2-CE1 3.47Å; Y527-H545 WeakPolarHBondContact CD2-CE1 3.33Å; Y527-H545 AromaticContact CD2-ND1 3.72Å; Y527-H545 AromaticContact CE2-CE1 3.37Å; Y527-H545 WeakPolarHBondContact CE2-CE1 3.4Å; Y527-H545 AromaticContact CE2-NE2 3.87Å; G543-H545 PolarHBondContact O-N 2.91Å; G543-H545 VanDerWaalsContact O-N 3.13Å; H545-L547 PolarHBondContact O-N 2.97Å; H545-T548 WeakPolarHBondContact O-CB 3.47Å; H545-T548 PolarHBondContact O-N 2.52Å; H545-A549 PolarHBondContact O-N 2.82Å
546T98.9Very high98.7Very high1 Ų117.5 Ų17.51%0.0068%0.082CC..Hα-helixtrans-55.5-50175.9-59.10000111.6M375 I524 T540 Y542 G543 T548 A549 Y550M375-T546 HydrophobicContact CE-CG2 4.47Å; I524-T546 HydrophobicContact CG1-CG2 4.23Å; I524-T546 HydrophobicContact CG2-CG2 4.25Å; T540-T546 HydrophobicContact CG2-CG2 4.08Å; T540-T546 WeakPolarHBondContact CG2-OG1 3.42Å; Y542-T546 WeakPolarHBondContact CA-OG1 3.41Å; Y542-T546 WeakPolarHBondContact CB-OG1 3.38Å; Y542-T546 HydrophobicContact CD2-CG2 4.11Å; Y542-T546 PolarHBondContact N-OG1 3.24Å; G543-T546 PolarHBondContact N-OG1 3.41Å; G543-T546 WeakPolarHBondContact O-CB 3.45Å; G543-T546 PolarHBondContact O-N 2.81Å; G543-T546 VanDerWaalsContact O-N 3.14Å; G543-T546 PolarHBondContact O-OG1 3.41Å; T546-T548 PolarHBondContact O-N 3.41Å; T546-A549 PolarHBondContact O-N 3.36Å; T546-Y550 HydrophobicContact CG2-CD2 3.88Å; T546-Y550 HydrophobicContact CG2-CE2 3.57Å; T546-Y550 VanDerWaalsContact O-CD2 3.31Å; T546-Y550 WeakPolarHBondContact O-CD2 3.49Å; T546-Y550 PolarHBondContact O-N 3.47Å; T546-Y550 VanDerWaalsContact O-N 3.11Å
547L98.9Very high98.7Very high3 Ų317.3 Ų17.32%0.0168%0.081CC..Hα-helixtrans-62.7-42.6177.117863.1000111.5M484 I524 T525 T526 H545 A549 Y550 L551M484-L547 HydrophobicContact CE-CD1 4.3Å; I524-L547 HydrophobicContact CG2-CB 3.95Å; I524-L547 HydrophobicContact CG2-CD1 4.07Å; T525-L547 WeakPolarHBondContact O-CB 3.13Å; T526-L547 HydrophobicContact CG2-CD2 3.86Å; H545-L547 PolarHBondContact O-N 2.97Å; L547-A549 VanDerWaalsContact C-N 3.29Å; L547-A549 PolarHBondContact O-N 2.9Å; L547-Y550 PolarHBondContact O-N 3.03Å; L547-Y550 VanDerWaalsContact O-N 3.15Å; L547-L551 HydrophobicContact CD1-CD1 4.49Å; L547-L551 HydrophobicContact CD1-CD2 4.36Å; L547-L551 HydrophobicContact CD1-CG 4.08Å; L547-L551 HydrophobicContact CD2-CD1 4.48Å; L547-L551 HydrophobicContact CG-CD1 4.02Å; L547-L551 HydrophobicContact CG-CG 4.09Å; L547-L551 VanDerWaalsContact O-CG 3.29Å; L547-L551 WeakPolarHBondContact O-CG 3.3Å; L547-L551 PolarHBondContact O-N 2.87Å
548T98.7Very high98.7Very high30 Ų3017.2 Ų17.218%0.1848%0.08CC..Hα-helixtrans-55.5-44.9177.4-59.10000111.9V380 I382 V388 H545 T546 L551 H552V380-T548 HydrophobicContact CB-CG2 4.08Å; V380-T548 HydrophobicContact CG1-CG2 3.97Å; V380-T548 HydrophobicContact CG2-CG2 4.3Å; I382-T548 HydrophobicContact CD1-CG2 3.49Å; I382-T548 VanDerWaalsContact CD1-CG2 3.49Å; V388-T548 HydrophobicContact CG2-CG2 4.04Å; H545-T548 WeakPolarHBondContact O-CB 3.47Å; H545-T548 PolarHBondContact O-N 2.52Å; T546-T548 PolarHBondContact O-N 3.41Å; T548-L551 PolarHBondContact O-N 2.87Å; T548-H552 WeakPolarHBondContact O-CB 3.4Å; T548-H552 PolarHBondContact O-N 3.29Å
549A98.8Very high98.6Very high1 Ų121.9 Ų21.91%0.00810%0.1CC..Hα-helixtrans-62.9-44.6176.400000112.1M375 V378 T390 H545 T546 L547 H552 K553M375-A549 HydrophobicContact CE-CB 4.02Å; V378-A549 HydrophobicContact CB-CB 4.04Å; V378-A549 HydrophobicContact CG1-CB 3.8Å; T390-A549 HydrophobicContact CG2-CB 3.44Å; T390-A549 VanDerWaalsContact CG2-CB 3.44Å; H545-A549 PolarHBondContact O-N 2.82Å; T546-A549 PolarHBondContact O-N 3.36Å; L547-A549 VanDerWaalsContact C-N 3.29Å; L547-A549 PolarHBondContact O-N 2.9Å; A549-H552 PolarHBondContact O-N 3.47Å; A549-K553 WeakPolarHBondContact O-CG 3.37Å; A549-K553 PolarHBondContact O-N 2.77Å
550Y98.9Very high98.6Very high0 Ų022.2 Ų22.20%010%0.103CC..Hα-helixtrans-63.2-44.5175.3-76.2-53.7000112.4M375 V467 P481 M484 T521 I524 T546 L547 H552 K553 Y554M375-Y550 HydrophobicContact CE-CD1 4.29Å; M375-Y550 HydrophobicContact CE-CD2 4.29Å; M375-Y550 HydrophobicContact CE-CE1 3.88Å; M375-Y550 HydrophobicContact CE-CE2 3.9Å; M375-Y550 HydrophobicContact CE-CG 4.48Å; M375-Y550 HydrophobicContact SD-CE1 4.07Å; V467-Y550 HydrophobicContact CG1-CD1 4.09Å; V467-Y550 HydrophobicContact CG1-CE1 4.06Å; P481-Y550 HydrophobicContact CG-CE1 3.85Å; P481-Y550 WeakPolarHBondContact CG-OH 2.87Å; M484-Y550 HydrophobicContact CE-CD2 4.25Å; M484-Y550 HydrophobicContact CE-CG 4.31Å; T521-Y550 PolarHBondContact OG1-OH 2.86Å; I524-Y550 HydrophobicContact CD1-CE2 4.39Å; I524-Y550 HydrophobicContact CG1-CD2 3.99Å; I524-Y550 HydrophobicContact CG1-CE2 3.62Å; I524-Y550 HydrophobicContact CG2-CD2 4.06Å; I524-Y550 HydrophobicContact CG2-CE2 4.48Å; T546-Y550 HydrophobicContact CG2-CD2 3.88Å; T546-Y550 HydrophobicContact CG2-CE2 3.57Å; T546-Y550 VanDerWaalsContact O-CD2 3.31Å; T546-Y550 WeakPolarHBondContact O-CD2 3.49Å; T546-Y550 PolarHBondContact O-N 3.47Å; T546-Y550 VanDerWaalsContact O-N 3.11Å; L547-Y550 PolarHBondContact O-N 3.03Å; L547-Y550 VanDerWaalsContact O-N 3.15Å; Y550-H552 VanDerWaalsContact C-N 3.26Å; Y550-H552 PolarHBondContact O-N 2.71Å; Y550-K553 PolarHBondContact O-N 3.13Å; Y550-Y554 HydrophobicContact CD1-CD2 4.44Å; Y550-Y554 AromaticContact CD1-CE2 3.87Å; Y550-Y554 HydrophobicContact CD1-CE2 3.87Å; Y550-Y554 HydrophobicContact CG-CE2 4.39Å; Y550-Y554 WeakPolarHBondContact O-CB 3.3Å; Y550-Y554 WeakPolarHBondContact O-CD2 3.36Å; Y550-Y554 PolarHBondContact O-N 3Å
551L98.8Very high98.5Very high33 Ų3322.2 Ų22.217%0.17310%0.103CC..Hα-helixtrans-55.8-44.6174.9-69.2174.5000110.9R491 L492 A495 L547 T548 R555R491-L551 HydrophobicContact CB-CD2 4.24Å; L492-L551 VanDerWaalsContact CA-CD2 3.46Å; L492-L551 HydrophobicContact CB-CD2 3.99Å; L492-L551 HydrophobicContact CD1-CD2 3.97Å; A495-L551 HydrophobicContact CB-CD2 3.92Å; L547-L551 HydrophobicContact CD1-CD1 4.49Å; L547-L551 HydrophobicContact CD1-CD2 4.36Å; L547-L551 HydrophobicContact CD1-CG 4.08Å; L547-L551 HydrophobicContact CD2-CD1 4.48Å; L547-L551 HydrophobicContact CG-CD1 4.02Å; L547-L551 HydrophobicContact CG-CG 4.09Å; L547-L551 VanDerWaalsContact O-CG 3.29Å; L547-L551 WeakPolarHBondContact O-CG 3.3Å; L547-L551 PolarHBondContact O-N 2.87Å; T548-L551 PolarHBondContact O-N 2.87Å; L551-R555 WeakPolarHBondContact O-CB 3.48Å; L551-R555 WeakPolarHBondContact O-CD 3.25Å; L551-R555 WeakPolarHBondContact O-CG 3.26Å; L551-R555 PolarHBondContact O-N 2.86Å; L551-R555 VanDerWaalsContact O-N 3.12Å
552H98.4Very high98.4Very high58 Ų5822.5 Ų22.527%0.26911%0.106SC..Hα-helixtrans-62.2-52177.4176.155.8000111.7V380 T548 A549 Y550 R555 E556V380-H552 HydrophobicContact CG1-CB 4.07Å; V380-H552 HydrophobicContact CG2-CB 3.91Å; T548-H552 WeakPolarHBondContact O-CB 3.4Å; T548-H552 PolarHBondContact O-N 3.29Å; A549-H552 PolarHBondContact O-N 3.47Å; Y550-H552 VanDerWaalsContact C-N 3.26Å; Y550-H552 PolarHBondContact O-N 2.71Å; H552-R555 PolarHBondContact O-N 2.81Å; H552-E556 IonicContact CE1-OE1 3.72Å; H552-E556 PolarHBondContact CE1-OE1 3.22Å; H552-E556 VanDerWaalsContact CE1-OE1 3.25Å; H552-E556 IonicContact NE2-OE1 3.71Å; H552-E556 PolarHBondContact NE2-OE1 3.49Å; H552-E556 IonicContact NE2-OE2 3.55Å; H552-E556 PolarHBondContact O-N 3.33Å; H552-E556 VanDerWaalsContact O-N 3.1Å
553K98.6Very high98.2Very high37 Ų3726.9 Ų26.916%0.16113%0.126CC..Hα-helixtrans-64.4-46.7-178-66.8-59.8171.3-163.60113.2V373 V467 A549 Y550 R555 E556 L557V373-K553 HydrophobicContact CG1-CG 4.35Å; V373-K553 HydrophobicContact CG2-CD 4.23Å; V373-K553 HydrophobicContact CG2-CG 4.24Å; V467-K553 HydrophobicContact CG2-CB 4.4Å; A549-K553 WeakPolarHBondContact O-CG 3.37Å; A549-K553 PolarHBondContact O-N 2.77Å; Y550-K553 PolarHBondContact O-N 3.13Å; K553-R555 VanDerWaalsContact C-N 3.28Å; K553-R555 PolarHBondContact O-N 2.98Å; K553-E556 VanDerWaalsContact CD-OE2 3.31Å; K553-E556 WeakPolarHBondContact CD-OE2 3.14Å; K553-E556 IonicContact NZ-OE2 2.76Å; K553-E556 PolarHBondContact NZ-OE2 3Å; K553-E556 WeakPolarHBondContact O-CB 3.29Å; K553-E556 PolarHBondContact O-N 3.18Å; K553-L557 WeakPolarHBondContact O-CD1 3.17Å; K553-L557 PolarHBondContact O-N 3.17Å
554Y98.8Very high97.9Very high0 Ų030.9 Ų30.90%015%0.147CC..Hα-helixtrans-66.2-29177.8-77.1-66.5000113.6V467 I469 V478 A479 V480 L492 Y550 A558V467-Y554 HydrophobicContact CB-CE1 3.99Å; V467-Y554 HydrophobicContact CB-CE2 4.41Å; V467-Y554 HydrophobicContact CG1-CE2 4.15Å; I469-Y554 HydrophobicContact CD1-CD1 3.94Å; I469-Y554 HydrophobicContact CG1-CD1 3.74Å; I469-Y554 HydrophobicContact CG1-CE1 4.18Å; V478-Y554 HydrophobicContact CG1-CD1 3.5Å; V478-Y554 VanDerWaalsContact CG1-CD1 3.5Å; V478-Y554 HydrophobicContact CG1-CD2 4.37Å; V478-Y554 HydrophobicContact CG1-CE1 3.43Å; V478-Y554 VanDerWaalsContact CG1-CE1 3.43Å; V478-Y554 HydrophobicContact CG1-CE2 4.35Å; V478-Y554 HydrophobicContact CG1-CG 4Å; A479-Y554 PolarHBondContact O-OH 2.99Å; V480-Y554 HydrophobicContact CG2-CE2 4.45Å; L492-Y554 HydrophobicContact CD1-CD2 3.68Å; L492-Y554 HydrophobicContact CD1-CG 3.87Å; L492-Y554 HydrophobicContact CD2-CD2 3.88Å; L492-Y554 HydrophobicContact CD2-CE2 4.17Å; L492-Y554 HydrophobicContact CD2-CG 4.47Å; L492-Y554 HydrophobicContact CG-CD2 4.45Å; Y550-Y554 HydrophobicContact CD1-CD2 4.44Å; Y550-Y554 AromaticContact CD1-CE2 3.87Å; Y550-Y554 HydrophobicContact CD1-CE2 3.87Å; Y550-Y554 HydrophobicContact CG-CE2 4.39Å; Y550-Y554 WeakPolarHBondContact O-CB 3.3Å; Y550-Y554 WeakPolarHBondContact O-CD2 3.36Å; Y550-Y554 PolarHBondContact O-N 3Å; Y554-A558 WeakPolarHBondContact O-CB 3.49Å; Y554-A558 PolarHBondContact O-N 3.37Å
555R98.4Very high97.8Very high86 Ų8634.4 Ų34.433%0.32516%0.162SC..Hα-helixtrans-66.4-40.1170.2-73.2166.271.693.65.1111.8A495 E499 L551 H552 K553 A558 K559A495-R555 HydrophobicContact CB-CG 4.02Å; E499-R555 HydrophobicContact CG-CB 3.91Å; E499-R555 HydrophobicContact CG-CG 3.92Å; E499-R555 IonicContact OE1-CZ 3.91Å; E499-R555 IonicContact OE1-NE 3.57Å; E499-R555 IonicContact OE1-NH1 3.47Å; E499-R555 IonicContact OE1-NH2 2.7Å; E499-R555 PolarHBondContact OE1-NH2 3.42Å; L551-R555 WeakPolarHBondContact O-CB 3.48Å; L551-R555 WeakPolarHBondContact O-CD 3.25Å; L551-R555 WeakPolarHBondContact O-CG 3.26Å; L551-R555 PolarHBondContact O-N 2.86Å; L551-R555 VanDerWaalsContact O-N 3.12Å; H552-R555 PolarHBondContact O-N 2.81Å; K553-R555 VanDerWaalsContact C-N 3.28Å; K553-R555 PolarHBondContact O-N 2.98Å; R555-A558 PolarHBondContact O-N 3.04Å; R555-K559 WeakPolarHBondContact O-CB 3.29Å; R555-K559 PolarHBondContact O-N 3.22Å
556E98.1Very high97.8Very high64 Ų6434.1 Ų34.130%0.29916%0.163SC..Hα-helixtrans-59.7-48174.2-68.1-177.7145.600111H552 K553 K559 A560H552-E556 IonicContact CE1-OE1 3.72Å; H552-E556 PolarHBondContact CE1-OE1 3.22Å; H552-E556 VanDerWaalsContact CE1-OE1 3.25Å; H552-E556 IonicContact NE2-OE1 3.71Å; H552-E556 PolarHBondContact NE2-OE1 3.49Å; H552-E556 IonicContact NE2-OE2 3.55Å; H552-E556 PolarHBondContact O-N 3.33Å; H552-E556 VanDerWaalsContact O-N 3.1Å; K553-E556 VanDerWaalsContact CD-OE2 3.31Å; K553-E556 WeakPolarHBondContact CD-OE2 3.14Å; K553-E556 IonicContact NZ-OE2 2.76Å; K553-E556 PolarHBondContact NZ-OE2 3Å; K553-E556 WeakPolarHBondContact O-CB 3.29Å; K553-E556 PolarHBondContact O-N 3.18Å; E556-K559 PolarHBondContact O-N 3.28Å; E556-A560 WeakPolarHBondContact O-CB 3.46Å; E556-A560 PolarHBondContact O-N 3.08Å
557L98.7Very high97.6Very high0 Ų039.8 Ų39.80%020%0.203CC..Hα-helixtrans-60.3-50.1176.3-83.173.1000111.6A369 Q371 V467 I469 K553 K559 A560 I561 L569A369-L557 HydrophobicContact CB-CB 4.21Å; A369-L557 HydrophobicContact CB-CD2 4.35Å; A369-L557 HydrophobicContact CB-CG 4.11Å; Q371-L557 HydrophobicContact CG-CD1 4.16Å; V467-L557 HydrophobicContact CB-CD2 4.37Å; V467-L557 HydrophobicContact CG2-CD1 3.84Å; V467-L557 HydrophobicContact CG2-CD2 4.06Å; V467-L557 WeakPolarHBondContact O-CD2 3.3Å; I469-L557 HydrophobicContact CD1-CB 3.93Å; I469-L557 HydrophobicContact CG1-CB 4.28Å; I469-L557 HydrophobicContact CG1-CD2 4.32Å; K553-L557 WeakPolarHBondContact O-CD1 3.17Å; K553-L557 PolarHBondContact O-N 3.17Å; L557-K559 VanDerWaalsContact C-N 3.34Å; L557-K559 PolarHBondContact O-N 3.4Å; L557-A560 PolarHBondContact O-N 3.02Å; L557-I561 WeakPolarHBondContact O-CG1 3.39Å; L557-I561 PolarHBondContact O-N 3.09Å; L557-L569 HydrophobicContact CG-CD1 4.39Å
558A98.4Very high97.5Very high0 Ų045.7 Ų45.70%023%0.23CC..Hα-helixtrans-60.9-42.5-179.200000112.1I469 V496 E499 L500 Y554 R555 I561 A562I469-A558 HydrophobicContact CD1-CB 4.01Å; V496-A558 HydrophobicContact CG1-CB 4.01Å; E499-A558 HydrophobicContact CB-CB 3.82Å; L500-A558 HydrophobicContact CD2-CB 4.21Å; L500-A558 HydrophobicContact CG-CB 4.14Å; Y554-A558 WeakPolarHBondContact O-CB 3.49Å; Y554-A558 PolarHBondContact O-N 3.37Å; R555-A558 PolarHBondContact O-N 3.04Å; A558-I561 PolarHBondContact O-N 3.36Å; A558-A562 WeakPolarHBondContact O-CB 3.28Å; A558-A562 PolarHBondContact O-N 2.93Å
559K97.9Very high97.4Very high98 Ų9845.9 Ų45.943%0.42623%0.23SC..Hα-helixtrans-64.1-44176-177.1179.5178.1-175.20111.6R555 E556 L557 I561 A562 Q563R555-K559 WeakPolarHBondContact O-CB 3.29Å; R555-K559 PolarHBondContact O-N 3.22Å; E556-K559 PolarHBondContact O-N 3.28Å; L557-K559 VanDerWaalsContact C-N 3.34Å; L557-K559 PolarHBondContact O-N 3.4Å; K559-I561 VanDerWaalsContact C-N 3.33Å; K559-I561 PolarHBondContact O-N 2.93Å; K559-A562 PolarHBondContact O-N 2.77Å; K559-Q563 HydrophobicContact CG-CG 4.46Å; K559-Q563 WeakPolarHBondContact O-CB 3.2Å; K559-Q563 VanDerWaalsContact O-CG 3.28Å; K559-Q563 WeakPolarHBondContact O-CG 3.38Å; K559-Q563 PolarHBondContact O-N 2.92Å
560A97.8Very high97.2Very high6 Ų650.1 Ų50.15%0.0526%0.257CS..Hα-helixtrans-63.7-38.4177.100000112.1E556 L557 D564 K565 V566 L569E556-A560 WeakPolarHBondContact O-CB 3.46Å; E556-A560 PolarHBondContact O-N 3.08Å; L557-A560 PolarHBondContact O-N 3.02Å; A560-D564 WeakPolarHBondContact O-CA 3.37Å; A560-D564 PolarHBondContact O-N 2.77Å; A560-K565 PolarHBondContact O-N 2.96Å; A560-V566 HydrophobicContact CB-CG2 4.33Å; A560-L569 HydrophobicContact CB-CD1 3.62Å; A560-L569 HydrophobicContact CB-CD2 3.94Å; A560-L569 HydrophobicContact CB-CG 3.72Å
561I97.4Very high97.1Very high1 Ų154.1 Ų54.11%0.00528%0.282CS..Hα-helixtrans-62.7-50.2172.1-70.9169.3000110.7R367 A369 I469 T471 L500 F506 L557 A558 K559 Q563 D564 V566R367-I561 HydrophobicContact CB-CG2 3.78Å; R367-I561 HydrophobicContact CG-CG2 4.19Å; A369-I561 HydrophobicContact CB-CD1 3.78Å; A369-I561 HydrophobicContact CB-CG1 3.73Å; I469-I561 HydrophobicContact CB-CD1 3.75Å; I469-I561 HydrophobicContact CG2-CD1 3.7Å; T471-I561 HydrophobicContact CG2-CD1 4.34Å; T471-I561 HydrophobicContact CG2-CG2 3.98Å; L500-I561 HydrophobicContact CD2-CB 4.36Å; L500-I561 HydrophobicContact CD2-CG2 4.06Å; F506-I561 HydrophobicContact CE2-CG2 4.21Å; F506-I561 HydrophobicContact CZ-CG2 4.03Å; L557-I561 WeakPolarHBondContact O-CG1 3.39Å; L557-I561 PolarHBondContact O-N 3.09Å; A558-I561 PolarHBondContact O-N 3.36Å; K559-I561 VanDerWaalsContact C-N 3.33Å; K559-I561 PolarHBondContact O-N 2.93Å; I561-Q563 PolarHBondContact O-N 2.94Å; I561-D564 PolarHBondContact O-N 2.81Å; I561-D564 VanDerWaalsContact O-N 3.11Å; I561-V566 HydrophobicContact CG1-CG2 3.94Å
562A95.8Very high97Very high8 Ų854.3 Ų54.37%0.06629%0.291CS..Hα-helixtrans-59.8-34.8-177.600000112.5V503 F506 A558 K559V503-A562 HydrophobicContact CG2-CB 4.13Å; V503-A562 WeakPolarHBondContact CG2-O 3.29Å; F506-A562 HydrophobicContact CD2-CB 4.45Å; A558-A562 WeakPolarHBondContact O-CB 3.28Å; A558-A562 PolarHBondContact O-N 2.93Å; K559-A562 PolarHBondContact O-N 2.77Å
563Q95.1Very high97Very high93 Ų9354.4 Ų54.444%0.43530%0.297SS..THydrogen-bonded Turntrans-93.30.2-178.9-62179.7-14.200113.8K559 I561 K565K559-Q563 HydrophobicContact CG-CG 4.46Å; K559-Q563 WeakPolarHBondContact O-CB 3.2Å; K559-Q563 VanDerWaalsContact O-CG 3.28Å; K559-Q563 WeakPolarHBondContact O-CG 3.38Å; K559-Q563 PolarHBondContact O-N 2.92Å; I561-Q563 PolarHBondContact O-N 2.94Å; Q563-K565 HydrophobicContact CB-CB 4.35Å; Q563-K565 HydrophobicContact CB-CD 3.96Å; Q563-K565 HydrophobicContact CB-CG 4.18Å; Q563-K565 PolarHBondContact O-N 3.47Å
564D93.1Very high96.9Very high83 Ų8359.6 Ų59.644%0.44432%0.322SS..THydrogen-bonded Turntrans50.840.6-171.6-154.830.6000113.3R94 R367 A560 I561R94-D564 IonicContact CZ-OD1 2.74Å; R94-D564 IonicContact NH1-OD1 3.47Å; R94-D564 IonicContact NH2-OD1 2.78Å; R94-D564 PolarHBondContact NH2-OD1 2.96Å; R94-D564 IonicContact NH2-OD2 2.64Å; R367-D564 IonicContact NE-OD1 3.19Å; R367-D564 PolarHBondContact NE-OD1 3.09Å; A560-D564 WeakPolarHBondContact O-CA 3.37Å; A560-D564 PolarHBondContact O-N 2.77Å; I561-D564 PolarHBondContact O-N 2.81Å; I561-D564 VanDerWaalsContact O-N 3.11Å
565K96.4Very high96.9Very high83 Ų8360 Ų6036%0.36133%0.325SS..  trans-114.225.5-178.3-75.4175.5158.8-104.10112.8A560 Q563 S567 E568A560-K565 PolarHBondContact O-N 2.96Å; Q563-K565 HydrophobicContact CB-CB 4.35Å; Q563-K565 HydrophobicContact CB-CD 3.96Å; Q563-K565 HydrophobicContact CB-CG 4.18Å; Q563-K565 PolarHBondContact O-N 3.47Å; K565-S567 PolarHBondContact O-N 2.65Å; K565-E568 HydrophobicContact CB-CG 4.25Å; K565-E568 WeakPolarHBondContact CD-OE2 3.42Å; K565-E568 VanDerWaalsContact NZ-CD 3.29Å; K565-E568 IonicContact NZ-OE1 3.81Å; K565-E568 PolarHBondContact NZ-OE1 2.9Å; K565-E568 IonicContact NZ-OE2 3.67Å; K565-E568 PolarHBondContact NZ-OE2 2.74Å; K565-E568 WeakPolarHBondContact O-CB 3.22Å; K565-E568 PolarHBondContact O-N 3.31Å
566V97.1Very high96.9Very high31 Ų3158.2 Ų58.219%0.18832%0.324CS..G310 helixtrans-58.6-34.7-178.2178.10000111.9F368 A369 A560 I561 E568 L569F368-V566 WeakPolarHBondContact O-CG1 3.35Å; A369-V566 HydrophobicContact CB-CG1 3.8Å; A369-V566 HydrophobicContact CB-CG2 4.01Å; A560-V566 HydrophobicContact CB-CG2 4.33Å; I561-V566 HydrophobicContact CG1-CG2 3.94Å; V566-E568 PolarHBondContact O-N 3.18Å; V566-L569 HydrophobicContact CG1-CD1 4.46Å; V566-L569 WeakPolarHBondContact O-CB 3.45Å; V566-L569 PolarHBondContact O-N 3.14Å
567S95.7Very high96.9Very high121 Ų12159.5 Ų59.585%0.84633%0.329SS*.G310 helixtrans-65.4-14.8176.356.20000114.4K565K565-S567 PolarHBondContact O-N 2.65Å
568E96.4Very high96.8Very high127 Ų12761 Ų6159%0.59334%0.335SS*.G310 helixtrans-86.4-11.3175.5-57.7179.1-173.100112K565 V566K565-E568 HydrophobicContact CB-CG 4.25Å; K565-E568 WeakPolarHBondContact CD-OE2 3.42Å; K565-E568 VanDerWaalsContact NZ-CD 3.29Å; K565-E568 IonicContact NZ-OE1 3.81Å; K565-E568 PolarHBondContact NZ-OE1 2.9Å; K565-E568 IonicContact NZ-OE2 3.67Å; K565-E568 PolarHBondContact NZ-OE2 2.74Å; K565-E568 WeakPolarHBondContact O-CB 3.22Å; K565-E568 PolarHBondContact O-N 3.31Å; V566-E568 PolarHBondContact O-N 3.18Å
569L96.3Very high96.6Very high33 Ų3366.6 Ų66.617%0.17337%0.37CS..SBendtrans-72.3137.2177-69.4177.2000110.6A369 L557 A560 V566 V571A369-L569 HydrophobicContact CB-CD1 4.14Å; L557-L569 HydrophobicContact CG-CD1 4.39Å; A560-L569 HydrophobicContact CB-CD1 3.62Å; A560-L569 HydrophobicContact CB-CD2 3.94Å; A560-L569 HydrophobicContact CB-CG 3.72Å; V566-L569 HydrophobicContact CG1-CD1 4.46Å; V566-L569 WeakPolarHBondContact O-CB 3.45Å; V566-L569 PolarHBondContact O-N 3.14Å; L569-V571 PolarHBondContact O-N 2.88Å
570P95.9Very high96.4Very high91 Ų9165.4 Ų65.459%0.59137%0.374SS*.  trans-66.1135170.525.7-31.6000109.8Q371 G572Q371-P570 WeakPolarHBondContact CG-O 3.44Å; Q371-P570 VanDerWaalsContact NE2-CD 3.27Å; Q371-P570 PolarHBondContact NE2-O 3.5Å; P570-G572 PolarHBondContact O-N 3.22Å
571V95.9Very high96.1Very high84 Ų8469.7 Ų69.751%0.50940%0.396SS..  trans-61.5-36176.7-179.80000111.3W372 L569W372-V571 HydrophobicContact CE3-CG1 3.84Å; W372-V571 HydrophobicContact CZ3-CG1 3.78Å; W372-V571 PolarHBondContact N-O 3.24Å; L569-V571 PolarHBondContact O-N 2.88Å
572G97.1Very high96Very high37 Ų3771.8 Ų71.838%0.38141%0.407SS..  trans83.9178.6-176.300000113.5W372 P570W372-G572 WeakPolarHBondContact O-CA 3.33Å; P570-G572 PolarHBondContact O-N 3.22Å
573P97.9Very high96Very high60 Ų6073.4 Ų73.439%0.3941%0.412SS..PPolyproline II helixtrans-71.9132.3-177.728.9-35.4000111.5W372 N374 I464W372-P573 WeakPolarHBondContact CB-O 3.39Å; W372-P573 WeakPolarHBondContact O-CD 3.48Å; N374-P573 HydrophobicContact CB-CG 4.25Å; I464-P573 HydrophobicContact CD1-CB 4.08Å; I464-P573 HydrophobicContact CD1-CG 3.57Å; I464-P573 HydrophobicContact CG1-CG 4.34Å; I464-P573 HydrophobicContact CG2-CG 4.35Å; I464-P573 WeakPolarHBondContact CG2-O 3.42Å
574E97.6Very high96Very high146 Ų14672.9 Ų72.968%0.68241%0.413SS*.PPolyproline II helixtrans-65.7138.7175.5-166.4173.8-177.200111.4W372W372-E574 HydrophobicContact CE3-CB 4.38Å; W372-E574 HydrophobicContact CH2-CG 4.15Å; W372-E574 HydrophobicContact CZ3-CB 4.27Å; W372-E574 HydrophobicContact CZ3-CG 4.15Å
575P98.3Very high96Very high8 Ų874.5 Ų74.55%0.05242%0.421CS..PPolyproline II helixtrans-71151.5177.329.6-36.5000111.5Q108 L112 I464Q108-P575 HydrophobicContact CG-CB 3.97Å; Q108-P575 HydrophobicContact CG-CG 4.39Å; Q108-P575 VanDerWaalsContact NE2-CB 3.33Å; L112-P575 HydrophobicContact CD1-CG 4.25Å; L112-P575 HydrophobicContact CD2-CG 4.15Å; I464-P575 HydrophobicContact CB-CB 4.15Å; I464-P575 HydrophobicContact CG2-CB 3.97Å
576P98Very high95.8Very high49 Ų4971.7 Ų71.732%0.31841%0.409SS..PPolyproline II helixtrans-70.7148.8177.430.5-35.6000111.9Q147 F578Q147-P576 PolarHBondContact NE2-O 3.03Å; Q147-P576 PolarHBondContact OE1-O 2.86Å; P576-F578 HydrophobicContact CB-CD1 4.2Å; P576-F578 HydrophobicContact CB-CE1 3.54Å; P576-F578 HydrophobicContact CB-CZ 3.85Å; P576-F578 HydrophobicContact CG-CE1 3.89Å; P576-F578 HydrophobicContact CG-CE2 4.4Å; P576-F578 HydrophobicContact CG-CZ 3.63Å
577F97.8Very high95.5Very high90 Ų9073.6 Ų73.640%0.39543%0.429SS..  trans-118.6103.7168-171.9-97.4000109.7R109 L112 E113 T579R109-F577 HydrophobicContact CG-CE2 4.19Å; L112-F577 HydrophobicContact CB-CD2 3.79Å; L112-F577 HydrophobicContact CB-CE2 4.1Å; L112-F577 HydrophobicContact CD1-CB 4.26Å; L112-F577 HydrophobicContact CD1-CD2 3.87Å; L112-F577 HydrophobicContact CG-CD2 4.5Å; E113-F577 HydrophobicContact CG-CE2 3.78Å; E113-F577 HydrophobicContact CG-CZ 3.91Å; F577-T579 HydrophobicContact CD1-CG2 3.79Å; F577-T579 HydrophobicContact CE1-CG2 3.93Å; F577-T579 PolarHBondContact O-N 3.08Å
578F97.3Very high95.1Very high31 Ų3173.2 Ų73.214%0.13642%0.423CS..  trans-79.2120.9-174.6-54.8-48.6000111.2R109 Q147 Y148 L458 P459 P576R109-F578 PolarHBondContact NH1-O 3.43Å; Q147-F578 HydrophobicContact CB-CD2 3.81Å; Q147-F578 HydrophobicContact CG-CD2 3.76Å; Q147-F578 HydrophobicContact CG-CE2 4.07Å; Q147-F578 WeakPolarHBondContact O-CD2 3.34Å; Q147-F578 VanDerWaalsContact OE1-N 3.1Å; Y148-F578 AromaticContact CD1-CE2 3.99Å; Y148-F578 HydrophobicContact CD1-CE2 3.99Å; Y148-F578 AromaticContact CE1-CE2 3.83Å; Y148-F578 HydrophobicContact CE1-CE2 3.83Å; Y148-F578 HydrophobicContact CE1-CZ 4.18Å; L458-F578 HydrophobicContact CB-CD2 4.48Å; L458-F578 HydrophobicContact CD1-CB 3.93Å; L458-F578 HydrophobicContact CD1-CD2 3.86Å; L458-F578 HydrophobicContact CD1-CG 3.98Å; L458-F578 HydrophobicContact CD2-CB 4.2Å; L458-F578 HydrophobicContact CD2-CD1 3.86Å; L458-F578 HydrophobicContact CD2-CD2 4.16Å; L458-F578 HydrophobicContact CD2-CE1 4.28Å; L458-F578 HydrophobicContact CD2-CG 3.81Å; L458-F578 HydrophobicContact CG-CD2 4.4Å; L458-F578 HydrophobicContact CG-CG 4.45Å; P459-F578 HydrophobicContact CB-CZ 4.46Å; P459-F578 HydrophobicContact CG-CZ 3.86Å; P576-F578 HydrophobicContact CB-CD1 4.2Å; P576-F578 HydrophobicContact CB-CE1 3.54Å; P576-F578 HydrophobicContact CB-CZ 3.85Å; P576-F578 HydrophobicContact CG-CE1 3.89Å; P576-F578 HydrophobicContact CG-CE2 4.4Å; P576-F578 HydrophobicContact CG-CZ 3.63Å
579T94.5Very high94.8Very high119 Ų11967.7 Ų67.773%0.7340%0.399SS*.  trans-105.2-22.1177.454.10000113.2F577F577-T579 HydrophobicContact CD1-CG2 3.79Å; F577-T579 HydrophobicContact CE1-CG2 3.93Å; F577-T579 PolarHBondContact O-N 3.08Å
580S93.3Very high94.6Very high73 Ų7368.7 Ų68.751%0.5141%0.412SS..SBendtrans-111.8166.6174.4680000111.2L582S580-L582 PolarHBondContact O-N 3.26Å
581N92.3Very high94.5Very high95 Ų9565.7 Ų65.751%0.50839%0.392SS..SBendtrans65.34.2174.7-55.825.7000115.8P457 L458 F583P457-N581 HydrophobicContact CB-CB 4.48Å; P457-N581 PolarHBondContact O-ND2 3.29Å; L458-N581 HydrophobicContact CD1-CB 4.26Å; L458-N581 HydrophobicContact CD2-CB 4.08Å; L458-N581 HydrophobicContact CG-CB 3.94Å; N581-F583 PolarHBondContact O-N 3.44Å
582L94.9Very high94.6Very high45 Ų4562.2 Ų62.224%0.23637%0.37CS..  trans-64.5125.6163.3-61.5173.3000108.5Q147 M152 Y158 L458 S580Q147-L582 HydrophobicContact CB-CD2 4.33Å; M152-L582 HydrophobicContact CE-CD2 4.38Å; M152-L582 HydrophobicContact SD-CD2 3.72Å; Y158-L582 HydrophobicContact CD1-CD1 4.12Å; Y158-L582 HydrophobicContact CG-CD1 4.27Å; L458-L582 HydrophobicContact CD1-CD2 4.07Å; S580-L582 PolarHBondContact O-N 3.26Å
583F94.4Very high94.5Very high42 Ų4265.4 Ų65.418%0.18437%0.371CS..  trans-106.2155.917860.5-98.5000111T149 M152 L153 G157 Y158 P457 N581 L585T149-F583 HydrophobicContact CG2-CE1 4.46Å; M152-F583 HydrophobicContact CB-CE1 3.95Å; M152-F583 HydrophobicContact CB-CE2 3.99Å; M152-F583 HydrophobicContact CB-CZ 3.48Å; M152-F583 VanDerWaalsContact CB-CZ 3.48Å; M152-F583 HydrophobicContact CE-CD1 4.16Å; M152-F583 HydrophobicContact CE-CE1 3.76Å; M152-F583 HydrophobicContact CE-CZ 4.44Å; M152-F583 HydrophobicContact SD-CE1 4.44Å; L153-F583 HydrophobicContact CD2-CE2 4.49Å; L153-F583 HydrophobicContact CD2-CZ 3.86Å; L153-F583 HydrophobicContact CG-CZ 4.2Å; G157-F583 CarbonylContact C-O 3.57Å; G157-F583 WeakPolarHBondContact CA-O 3.42Å; Y158-F583 PolarHBondContact N-O 3.22Å; P457-F583 HydrophobicContact CG-CD1 4.17Å; P457-F583 HydrophobicContact CG-CE1 4.2Å; N581-F583 PolarHBondContact O-N 3.44Å; F583-L585 HydrophobicContact CD2-CD1 4.11Å; F583-L585 HydrophobicContact CD2-CD2 4.26Å; F583-L585 HydrophobicContact CD2-CG 3.77Å; F583-L585 HydrophobicContact CE2-CD1 3.99Å; F583-L585 HydrophobicContact CE2-CG 4.14Å
584N95.2Very high94.4Very high83 Ų8366.9 Ų66.944%0.44437%0.371SS..BIsolated β-bridgetrans-135.6112.9168.8-177.1-10.2000108.2M586N584-M586 WeakPolarHBondContact OD1-CB 3.3Å; N584-M586 PolarHBondContact OD1-N 2.9Å
585L93.4Very high94.2Very high116 Ų11661.5 Ų61.561%0.60735%0.349SS*.  trans-952.2-177.7-55.5176.6000112.3K156 F583K156-L585 HydrophobicContact CB-CB 4.3Å; K156-L585 PolarHBondContact O-N 3.43Å; F583-L585 HydrophobicContact CD2-CD1 4.11Å; F583-L585 HydrophobicContact CD2-CD2 4.26Å; F583-L585 HydrophobicContact CD2-CG 3.77Å; F583-L585 HydrophobicContact CE2-CD1 3.99Å; F583-L585 HydrophobicContact CE2-CG 4.14Å
586M92.8Very high93.9Very high24 Ų2467.2 Ų67.212%0.11838%0.384CS..PPolyproline II helixtrans-76.1134.3176.2-63.7-150.9-52.900111.2I63 K156 I159 N584I63-M586 HydrophobicContact CD1-CE 4.47Å; I63-M586 HydrophobicContact CG1-CE 4.02Å; I63-M586 HydrophobicContact CG1-SD 4.22Å; K156-M586 HydrophobicContact CB-CG 4.03Å; K156-M586 HydrophobicContact CD-CG 4.43Å; I159-M586 HydrophobicContact CB-CE 4.31Å; I159-M586 HydrophobicContact CD1-CE 3.59Å; I159-M586 HydrophobicContact CD1-CG 4.06Å; I159-M586 HydrophobicContact CD1-SD 3.55Å; I159-M586 VanDerWaalsContact CD1-SD 3.55Å; I159-M586 HydrophobicContact CG1-CE 3.84Å; I159-M586 HydrophobicContact CG1-CG 4.46Å; I159-M586 HydrophobicContact CG1-SD 4.33Å; I159-M586 HydrophobicContact CG2-CE 3.47Å; I159-M586 VanDerWaalsContact CG2-CE 3.47Å; N584-M586 WeakPolarHBondContact OD1-CB 3.3Å; N584-M586 PolarHBondContact OD1-N 2.9Å
587A90.2Very high93.7Very high72 Ų7272.8 Ų72.860%0.59541%0.411SS*.PPolyproline II helixtrans-62.1142.3168.400000110.6R627A587-R627 PolarHBondContact O-NH1 2.75Å; A587-R627 PolarHBondContact O-NH2 3Å
588P88Confident93.6Very high113 Ų11369.2 Ų69.273%0.73440%0.397SS*.PPolyproline II helixtrans-55.9143.7168-23.833.7000111A590P588-A590 PolarHBondContact O-N 3.25Å
589A90.4Very high93.6Very high11 Ų1170.4 Ų70.49%0.09141%0.409CS..PPolyproline II helixtrans-61.8123.9173.500000109.6R627 H628 K699A589-R627 HydrophobicContact CB-CB 4.1Å; A589-H628 WeakPolarHBondContact CB-CE1 3.41Å; A589-K699 PolarHBondContact O-NZ 3.42Å
590A91.6Very high93.8Very high53 Ų5365.9 Ų65.944%0.43838%0.379SS..PPolyproline II helixtrans-68.3164-177.600000111.6P588 D592 H628P588-A590 PolarHBondContact O-N 3.25Å; A590-D592 PolarHBondContact O-N 2.92Å; A590-H628 PolarHBondContact O-CE1 3.01Å; A590-H628 PolarHBondContact O-NE2 2.85Å
591V94.5Very high94Very high28 Ų2862.7 Ų62.717%0.1736%0.358CS..PPolyproline II helixtrans-65.5128.8168.2162.50000109R671 K699 L701V591-R671 VanDerWaalsContact O-CD 3.27Å; V591-R671 WeakPolarHBondContact O-CD 3.34Å; V591-R671 PolarHBondContact O-NH1 3.49Å; V591-K699 CarbonylContact C-O 3.58Å; V591-K699 WeakPolarHBondContact CA-O 3.23Å; V591-K699 WeakPolarHBondContact CG1-O 3.49Å; V591-K699 HydrophobicContact CG2-CD 4.41Å; V591-K699 HydrophobicContact CG2-CG 4.21Å; V591-L701 HydrophobicContact CG2-CD1 4.22Å; V591-L701 HydrophobicContact CG2-CD2 4.38Å; V591-L701 HydrophobicContact CG2-CG 3.83Å
592D96.9Very high94.3Very high11 Ų1161.4 Ų61.46%0.05935%0.351CS..PPolyproline II helixtrans-75.9154.7-179.3-56.2-67.6000111A590 F600 N625 H628 N673 Y698 K699A590-D592 PolarHBondContact O-N 2.92Å; D592-F600 HydrophobicContact CB-CE1 3.87Å; D592-F600 HydrophobicContact CB-CZ 3.62Å; D592-N625 PolarHBondContact OD1-N 2.95Å; D592-N625 VanDerWaalsContact OD1-N 3.09Å; D592-H628 IonicContact OD1-NE2 3.67Å; D592-H628 IonicContact OD2-CD2 3.44Å; D592-H628 PolarHBondContact OD2-CD2 3.22Å; D592-H628 IonicContact OD2-NE2 3.57Å; D592-H628 PolarHBondContact OD2-NE2 3.04Å; D592-N673 PolarHBondContact OD1-ND2 3.07Å; D592-Y698 WeakPolarHBondContact OD2-CA 3.36Å; D592-K699 PolarHBondContact N-O 3.3Å; D592-K699 PolarHBondContact OD2-N 3.04Å
593R95.8Very high94.5Very high105 Ų10561.3 Ų61.340%0.39635%0.352SS..BIsolated β-bridgetrans-125.3160.1169.8-68.4-169171.4173-10.5109N670 R671 Q672R593-N670 VanDerWaalsContact CD-O 3.3Å; R593-N670 WeakPolarHBondContact CD-O 3.32Å; R593-N670 PolarHBondContact NH1-OD1 3Å; R593-R671 HydrophobicContact CB-CB 4.41Å; R593-R671 HydrophobicContact CG-CB 4.26Å; R593-R671 PolarHBondContact N-O 3Å; R593-R671 VanDerWaalsContact NE-NH2 3.19Å; R593-Q672 HydrophobicContact CB-CG 3.91Å; R593-Q672 WeakPolarHBondContact O-CA 3.23Å
594K94.9Very high94.6Very high90 Ų9062.9 Ų62.939%0.39136%0.362SS..  trans-119.4157.7172.258-176.7-169.3162.80110.1S598 S599 F600 V622 Q672K594-S598 WeakPolarHBondContact CD-O 3.43Å; K594-S598 WeakPolarHBondContact CE-O 3.4Å; K594-S598 PolarHBondContact NZ-O 3.34Å; K594-S599 PolarHBondContact NZ-OG 2.68Å; K594-F600 HydrophobicContact CB-CE2 4.38Å; K594-F600 HydrophobicContact CB-CZ 4.29Å; K594-F600 HydrophobicContact CD-CD2 4.38Å; K594-F600 HydrophobicContact CD-CE2 4.36Å; K594-V622 HydrophobicContact CB-CG1 3.86Å; K594-Q672 PolarHBondContact O-NE2 3.31Å
595P94.3Very high94.7Very high33 Ų3364.7 Ų64.721%0.21437%0.368CS..  trans-50.7156.8165.5-27.234.4000112.7N597 S598 L604 V622P595-N597 PolarHBondContact O-N 2.92Å; P595-S598 WeakPolarHBondContact CB-OG 3.48Å; P595-S598 VanDerWaalsContact CD-OG 3.29Å; P595-S598 WeakPolarHBondContact CD-OG 3.43Å; P595-S598 PolarHBondContact O-N 2.92Å; P595-S598 PolarHBondContact O-OG 2.76Å; P595-L604 HydrophobicContact CG-CD2 4.46Å; P595-V622 HydrophobicContact CG-CG2 4.26Å
596V92.4Very high94.9Very high129 Ų12962.5 Ų62.578%0.78236%0.355SS*.THydrogen-bonded Turntrans-65.1135.9176.3-1800000108.4S598V596-S598 PolarHBondContact O-N 3.12Å
597N92.6Very high95.2Very high165 Ų16562 Ų6288%0.88235%0.353SS*.THydrogen-bonded Turntrans61.818.5-178.7-56.1-23.5000116P595P595-N597 PolarHBondContact O-N 2.92Å
598S95.9Very high95.6Very high16 Ų1663.6 Ų63.611%0.11235%0.351CS..  trans-109.9178.9167.374.20000111.5K594 P595 V596 D602K594-S598 WeakPolarHBondContact CD-O 3.43Å; K594-S598 WeakPolarHBondContact CE-O 3.4Å; K594-S598 PolarHBondContact NZ-O 3.34Å; P595-S598 WeakPolarHBondContact CB-OG 3.48Å; P595-S598 VanDerWaalsContact CD-OG 3.29Å; P595-S598 WeakPolarHBondContact CD-OG 3.43Å; P595-S598 PolarHBondContact O-N 2.92Å; P595-S598 PolarHBondContact O-OG 2.76Å; V596-S598 PolarHBondContact O-N 3.12Å; S598-D602 WeakPolarHBondContact CA-OD2 3.44Å; S598-D602 WeakPolarHBondContact CB-OD2 3.25Å
599S97.3Very high96Very high55 Ų5562.8 Ų62.839%0.38535%0.345SS..  trans-129.4160.1170.9-67.80000110.7K594 G601 D602 V622K594-S599 PolarHBondContact NZ-OG 2.68Å; S599-G601 PolarHBondContact O-N 3.25Å; S599-D602 VanDerWaalsContact N-CG 3.34Å; S599-D602 PolarHBondContact N-OD2 2.86Å; S599-D602 WeakPolarHBondContact O-CB 3.42Å; S599-D602 PolarHBondContact O-N 3.27Å; S599-V622 WeakPolarHBondContact O-CB 3.4Å
600F98.2Very high96.4Very high25 Ų2564.4 Ų64.411%0.1135%0.354CS..THydrogen-bonded Turntrans-65.4132.7169.9-68.3-78.5000108.7D592 K594 V622 Y698 Y711D592-F600 HydrophobicContact CB-CE1 3.87Å; D592-F600 HydrophobicContact CB-CZ 3.62Å; K594-F600 HydrophobicContact CB-CE2 4.38Å; K594-F600 HydrophobicContact CB-CZ 4.29Å; K594-F600 HydrophobicContact CD-CD2 4.38Å; K594-F600 HydrophobicContact CD-CE2 4.36Å; F600-V622 HydrophobicContact CD1-CG1 4Å; F600-V622 HydrophobicContact CE1-CG1 4.43Å; F600-Y698 HydrophobicContact CB-CD1 3.96Å; F600-Y698 HydrophobicContact CB-CE1 4.38Å; F600-Y698 HydrophobicContact CD1-CD1 4.48Å; F600-Y698 HydrophobicContact CD1-CG 4.21Å; F600-Y698 AromaticContact CD2-CD1 3.41Å; F600-Y698 HydrophobicContact CD2-CD1 3.41Å; F600-Y698 VanDerWaalsContact CD2-CD1 3.41Å; F600-Y698 AromaticContact CD2-CD2 3.51Å; F600-Y698 HydrophobicContact CD2-CD2 3.51Å; F600-Y698 AromaticContact CD2-CE1 3.68Å; F600-Y698 HydrophobicContact CD2-CE1 3.68Å; F600-Y698 AromaticContact CD2-CE2 3.76Å; F600-Y698 HydrophobicContact CD2-CE2 3.76Å; F600-Y698 AromaticContact CD2-CG 3.32Å; F600-Y698 HydrophobicContact CD2-CG 3.32Å; F600-Y698 AromaticContact CD2-CZ 3.86Å; F600-Y698 HydrophobicContact CE1-CG 4.27Å; F600-Y698 AromaticContact CE2-CD1 3.99Å; F600-Y698 HydrophobicContact CE2-CD1 3.99Å; F600-Y698 AromaticContact CE2-CD2 3.17Å; F600-Y698 HydrophobicContact CE2-CD2 3.17Å; F600-Y698 HydrophobicContact CE2-CE1 4.36Å; F600-Y698 AromaticContact CE2-CE2 3.6Å; F600-Y698 HydrophobicContact CE2-CE2 3.6Å; F600-Y698 AromaticContact CE2-CG 3.4Å; F600-Y698 HydrophobicContact CE2-CG 3.4Å; F600-Y698 AromaticContact CG-CD1 3.71Å; F600-Y698 HydrophobicContact CG-CD1 3.71Å; F600-Y698 HydrophobicContact CG-CD2 4.38Å; F600-Y698 HydrophobicContact CG-CE1 4.28Å; F600-Y698 AromaticContact CG-CG 3.77Å; F600-Y698 HydrophobicContact CG-CG 3.77Å; F600-Y698 AromaticContact CZ-CD2 3.82Å; F600-Y698 HydrophobicContact CZ-CD2 3.82Å; F600-Y698 AromaticContact CZ-CG 3.89Å; F600-Y698 HydrophobicContact CZ-CG 3.89Å; F600-Y711 VanDerWaalsContact C-CD2 3.49Å; F600-Y711 HydrophobicContact CB-CD1 3.87Å; F600-Y711 HydrophobicContact CB-CD2 3.87Å; F600-Y711 HydrophobicContact CB-CE1 4.28Å; F600-Y711 HydrophobicContact CB-CE2 4.28Å; F600-Y711 HydrophobicContact CB-CG 3.64Å
601G98.1Very high96.6Very high6 Ų662.7 Ų62.76%0.06234%0.336CS..THydrogen-bonded Turntrans95.4-13.2-171.500000114.6S599 F621 V622 Y711 G713S599-G601 PolarHBondContact O-N 3.25Å; G601-F621 WeakPolarHBondContact O-CD1 3.24Å; G601-V622 PolarHBondContact N-O 3.32Å; G601-Y711 VanDerWaalsContact N-CD2 3.27Å; G601-G713 WeakPolarHBondContact O-CA 3.26Å
602D98.4Very high96.8Very high67 Ų6765.9 Ų65.936%0.35835%0.346SS..  trans-65141.1174.6-71.82.6000110.8S598 S599 F621 V622S598-D602 WeakPolarHBondContact CA-OD2 3.44Å; S598-D602 WeakPolarHBondContact CB-OD2 3.25Å; S599-D602 VanDerWaalsContact N-CG 3.34Å; S599-D602 PolarHBondContact N-OD2 2.86Å; S599-D602 WeakPolarHBondContact O-CB 3.42Å; S599-D602 PolarHBondContact O-N 3.27Å; D602-F621 CarbonylContact O-C 3Å; D602-F621 VanDerWaalsContact O-CA 3.31Å; D602-F621 WeakPolarHBondContact O-CA 3.45Å; D602-V622 HydrophobicContact CB-CG2 4.24Å; D602-V622 PolarHBondContact O-N 2.81Å
603V98.4Very high96.7Very high44 Ų4468.6 Ų68.627%0.26736%0.358SS..EExtended strand (participates in β ladder)trans-78.2126176.5-177.80000110.1E605 Q606 V619 T620 F621 S714V603-E605 VanDerWaalsContact CG1-O 3.27Å; V603-E605 WeakPolarHBondContact CG1-O 3.48Å; V603-Q606 HydrophobicContact CG1-CB 4.1Å; V603-V619 HydrophobicContact CG1-CG2 3.85Å; V603-V619 HydrophobicContact CG2-CG2 4.39Å; V603-T620 CarbonylContact C-O 3.55Å; V603-F621 HydrophobicContact CG2-CD1 3.82Å; V603-F621 HydrophobicContact CG2-CE1 3.64Å; V603-S714 WeakPolarHBondContact CG2-O 3.43Å
604L97Very high96.7Very high75 Ų7566.4 Ų66.439%0.39337%0.368SS..EExtended strand (participates in β ladder)trans-92.6-40.3174.1-65.4176.9000112P595 T620 V622 N674P595-L604 HydrophobicContact CG-CD2 4.46Å; L604-T620 HydrophobicContact CB-CG2 4.24Å; L604-T620 HydrophobicContact CD1-CG2 4.29Å; L604-T620 PolarHBondContact N-O 3.21Å; L604-V622 HydrophobicContact CD1-CG2 3.96Å; L604-V622 HydrophobicContact CD2-CG2 3.58Å; L604-V622 HydrophobicContact CG-CG2 3.71Å; L604-N674 WeakPolarHBondContact CD1-OD1 3.25Å
605E97.8Very high96.8Very high120 Ų12064.1 Ų64.156%0.56136%0.36SS*.EExtended strand (participates in β ladder)trans-130.8119.3177-62.7174163.700108V603 V619 T620V603-E605 VanDerWaalsContact CG1-O 3.27Å; V603-E605 WeakPolarHBondContact CG1-O 3.48Å; E605-V619 WeakPolarHBondContact O-CA 3.21Å; E605-V619 WeakPolarHBondContact O-CG2 3.23Å; E605-T620 PolarHBondContact N-O 3.32Å; E605-T620 PolarHBondContact O-N 2.85Å; E605-T620 PolarHBondContact OE2-OG1 3.03Å
606Q98.1Very high97Very high71 Ų7166.5 Ų66.533%0.33237%0.37SS..PPolyproline II helixtrans-92.4153.9-172.1-169.356-69.300112.5V603 D716V603-Q606 HydrophobicContact CG1-CB 4.1Å; Q606-D716 HydrophobicContact CG-CB 4.19Å; Q606-D716 WeakPolarHBondContact CG-OD2 3.44Å; Q606-D716 PolarHBondContact NE2-OD1 3.03Å; Q606-D716 PolarHBondContact NE2-OD2 3.11Å; Q606-D716 VanDerWaalsContact NE2-OD2 3.1Å
607V98.4Very high97.3Very high13 Ų1360.3 Ų60.38%0.07933%0.333CS..PPolyproline II helixtrans-62.2154.8170.7-59.20000112.3Y611 V617 V619 D716 F718V607-Y611 HydrophobicContact CB-CE2 4.25Å; V607-V617 HydrophobicContact CB-CG1 4.17Å; V607-V617 HydrophobicContact CG1-CG1 3.51Å; V607-V619 HydrophobicContact CG1-CB 3.85Å; V607-V619 HydrophobicContact CG1-CG1 4.49Å; V607-V619 HydrophobicContact CG1-CG2 4.47Å; V607-D716 HydrophobicContact CG2-CB 4.35Å; V607-F718 HydrophobicContact CB-CD1 4.14Å; V607-F718 HydrophobicContact CG1-CD1 4.24Å; V607-F718 HydrophobicContact CG1-CE1 4.32Å; V607-F718 HydrophobicContact CG2-CB 4.13Å; V607-F718 HydrophobicContact CG2-CD1 3.75Å; V607-F718 HydrophobicContact CG2-CG 4.26Å
608L97.9Very high97.6Very high106 Ų10654.5 Ų54.556%0.55531%0.305SS*.PPolyproline II helixtrans-75154166.6-60.6176.2000110.2V610 Y611 F718L608-V610 VanDerWaalsContact C-N 3.28Å; L608-V610 PolarHBondContact O-N 3.15Å; L608-Y611 HydrophobicContact CB-CE1 4.33Å; L608-Y611 HydrophobicContact CB-CE2 3.81Å; L608-Y611 HydrophobicContact CD1-CE1 4.29Å; L608-Y611 PolarHBondContact N-OH 2.93Å; L608-Y611 WeakPolarHBondContact O-CE2 3.31Å; L608-F718 WeakPolarHBondContact O-CB 2.95Å
609P97.4Very high97.7Very high95 Ų9553.7 Ų53.762%0.61730%0.299SS*.SBendtrans-70.8-19.5-178.126.9-35.3000114.3F718 S719P609-F718 WeakPolarHBondContact O-CA 3.22Å; P609-S719 PolarHBondContact O-N 3.31Å; P609-S719 PolarHBondContact O-OG 3.22Å
610V97.5Very high97.8Very high46 Ų4651.2 Ų51.228%0.27928%0.282SS..EExtended strand (participates in β ladder)trans-142.8133.5-175.6-1710000110.4L608 S719 Y724L608-V610 VanDerWaalsContact C-N 3.28Å; L608-V610 PolarHBondContact O-N 3.15Å; V610-S719 CarbonylContact C-O 3.34Å; V610-S719 WeakPolarHBondContact CA-O 2.96Å; V610-Y724 HydrophobicContact CG1-CD1 4.2Å
611Y97.8Very high97.8Very high16 Ų1650 Ų506%0.06328%0.277CS..EExtended strand (participates in β ladder)trans-131.2156.7173.6-69-90.2000111.1V607 L608 D615 I616 V617 I681 F718 S719 V720 G721V607-Y611 HydrophobicContact CB-CE2 4.25Å; L608-Y611 HydrophobicContact CB-CE1 4.33Å; L608-Y611 HydrophobicContact CB-CE2 3.81Å; L608-Y611 HydrophobicContact CD1-CE1 4.29Å; L608-Y611 PolarHBondContact N-OH 2.93Å; L608-Y611 WeakPolarHBondContact O-CE2 3.31Å; Y611-D615 HydrophobicContact CD1-CB 3.89Å; Y611-I616 WeakPolarHBondContact CE1-O 3.15Å; Y611-V617 HydrophobicContact CD1-CG2 4.02Å; Y611-V617 HydrophobicContact CD2-CG2 3.84Å; Y611-V617 HydrophobicContact CE1-CB 4.43Å; Y611-V617 HydrophobicContact CE1-CG2 4.1Å; Y611-V617 HydrophobicContact CE2-CB 4.36Å; Y611-V617 HydrophobicContact CE2-CG1 3.95Å; Y611-V617 HydrophobicContact CE2-CG2 3.9Å; Y611-V617 HydrophobicContact CG-CG2 3.88Å; Y611-I681 HydrophobicContact CG-CD1 4.19Å; Y611-F718 HydrophobicContact CD2-CB 4.35Å; Y611-F718 AromaticContact CD2-CD2 3.58Å; Y611-F718 HydrophobicContact CD2-CD2 3.58Å; Y611-F718 HydrophobicContact CD2-CE2 4.16Å; Y611-F718 HydrophobicContact CD2-CG 4.18Å; Y611-F718 HydrophobicContact CE2-CB 4.39Å; Y611-F718 HydrophobicContact CE2-CD2 4.02Å; Y611-F718 HydrophobicContact CE2-CG 4.24Å; Y611-S719 PolarHBondContact N-O 3.03Å; Y611-V720 WeakPolarHBondContact O-CA 3.24Å; Y611-G721 PolarHBondContact O-N 3.16Å
612R96.8Very high97.8Very high96 Ų9649.8 Ų49.836%0.36227%0.274SS..EExtended strand (participates in β ladder)trans-96.4154.5167.7-69.1168.6-168.4-174.92.4110.8G614 D615 G721 Y724R612-G614 PolarHBondContact O-N 3.38Å; R612-D615 PolarHBondContact N-OD2 2.82Å; R612-D615 VanDerWaalsContact O-CB 3.23Å; R612-D615 WeakPolarHBondContact O-CB 3.2Å; R612-D615 PolarHBondContact O-N 2.87Å; R612-G721 CarbonylContact C-O 3.47Å; R612-G721 VanDerWaalsContact CA-O 3.28Å; R612-G721 WeakPolarHBondContact CA-O 3.47Å; R612-Y724 HydrophobicContact CB-CE1 4.24Å; R612-Y724 HydrophobicContact CG-CD1 3.66Å; R612-Y724 HydrophobicContact CG-CE1 3.49Å; R612-Y724 VanDerWaalsContact CG-CE1 3.49Å; R612-Y724 HydrophobicContact CG-CE2 4.41Å; R612-Y724 HydrophobicContact CG-CG 4.16Å; R612-Y724 VanDerWaalsContact NE-CZ 3.29Å
613Q96.6Very high97.8Very high67 Ų6746.7 Ų46.731%0.31326%0.257SS..THydrogen-bonded Turntrans-50.6129.5159.4-71.3166.1-1700110.4I681 A685 V720 G721Q613-I681 HydrophobicContact CG-CG2 4.44Å; Q613-A685 PolarHBondContact NE2-O 3.18Å; Q613-V720 HydrophobicContact CG-CG1 4.34Å; Q613-G721 PolarHBondContact N-O 2.78Å
614G95Very high97.8Very high59 Ų5944.7 Ų44.761%0.60825%0.246SC*.THydrogen-bonded Turntrans91.7-12.3-172.900000115.2R612 I681R612-G614 PolarHBondContact O-N 3.38Å; G614-I681 VanDerWaalsContact CA-O 3.28Å; G614-I681 WeakPolarHBondContact CA-O 3.11Å; G614-I681 PolarHBondContact N-O 3.3Å
615D97.8Very high97.8Very high42 Ų4241.4 Ų41.423%0.22523%0.229CC..  trans-74.8166.9171.4-67.1-13.3000111Y611 R612 I681 Y724Y611-D615 HydrophobicContact CD1-CB 3.89Å; R612-D615 PolarHBondContact N-OD2 2.82Å; R612-D615 VanDerWaalsContact O-CB 3.23Å; R612-D615 WeakPolarHBondContact O-CB 3.2Å; R612-D615 PolarHBondContact O-N 2.87Å; D615-I681 HydrophobicContact CB-CD1 4.44Å; D615-I681 PolarHBondContact O-N 3.19Å; D615-Y724 PolarHBondContact OD1-OH 2.81Å; D615-Y724 WeakPolarHBondContact OD2-CE1 3.48Å; D615-Y724 PolarHBondContact OD2-OH 2.92Å
616I98.1Very high97.7Very high83 Ų8336 Ų3643%0.42620%0.204SC..EExtended strand (participates in β ladder)trans-112.1119.3175.7-54.4167.6000108Y611 E678 W679 F680Y611-I616 WeakPolarHBondContact CE1-O 3.15Å; I616-E678 HydrophobicContact CG2-CB 4.24Å; I616-W679 WeakPolarHBondContact CA-O 3.42Å; I616-F680 HydrophobicContact CD1-CD1 3.85Å; I616-F680 HydrophobicContact CD1-CE1 3.31Å; I616-F680 HydrophobicContact CD1-CZ 3.88Å; I616-F680 HydrophobicContact CG1-CD1 3.68Å; I616-F680 HydrophobicContact CG1-CE1 3.67Å; I616-F680 HydrophobicContact CG1-CG 4.31Å; I616-F680 HydrophobicContact CG1-CZ 4.27Å; I616-F680 HydrophobicContact CG2-CD2 4.47Å; I616-F680 HydrophobicContact CG2-CE1 4.37Å; I616-F680 HydrophobicContact CG2-CE2 4.2Å; I616-F680 HydrophobicContact CG2-CZ 4.13Å
617V98.5Very high97.6Very high0 Ų035.4 Ų35.40%020%0.199CC..EExtended strand (participates in β ladder)trans-83.9136.3168.8-172.90000107.9V607 Y611 E678 W679 I681 I692 F718V607-V617 HydrophobicContact CB-CG1 4.17Å; V607-V617 HydrophobicContact CG1-CG1 3.51Å; Y611-V617 HydrophobicContact CD1-CG2 4.02Å; Y611-V617 HydrophobicContact CD2-CG2 3.84Å; Y611-V617 HydrophobicContact CE1-CB 4.43Å; Y611-V617 HydrophobicContact CE1-CG2 4.1Å; Y611-V617 HydrophobicContact CE2-CB 4.36Å; Y611-V617 HydrophobicContact CE2-CG1 3.95Å; Y611-V617 HydrophobicContact CE2-CG2 3.9Å; Y611-V617 HydrophobicContact CG-CG2 3.88Å; V617-E678 CarbonylContact O-C 3.13Å; V617-E678 VanDerWaalsContact O-CA 3.24Å; V617-E678 WeakPolarHBondContact O-CA 3.19Å; V617-W679 HydrophobicContact CB-CB 4.3Å; V617-W679 HydrophobicContact CB-CE3 4.43Å; V617-W679 HydrophobicContact CG2-CE3 3.86Å; V617-W679 HydrophobicContact CG2-CZ3 4.47Å; V617-W679 PolarHBondContact N-O 2.98Å; V617-W679 PolarHBondContact O-N 3.01Å; V617-I681 HydrophobicContact CG2-CD1 3.61Å; V617-I681 HydrophobicContact CG2-CG1 3.93Å; V617-I692 HydrophobicContact CB-CD1 4.14Å; V617-I692 HydrophobicContact CG1-CD1 3.64Å; V617-F718 HydrophobicContact CB-CZ 4.38Å; V617-F718 HydrophobicContact CG1-CE1 4.08Å; V617-F718 HydrophobicContact CG1-CE2 4.18Å; V617-F718 HydrophobicContact CG1-CZ 3.81Å; V617-F718 HydrophobicContact CG2-CD2 4.4Å; V617-F718 HydrophobicContact CG2-CE2 3.63Å; V617-F718 HydrophobicContact CG2-CZ 3.93Å
618S98.4Very high97.5Very high42 Ų4235.5 Ų35.529%0.29420%0.198SC..EExtended strand (participates in β ladder)trans-136.1133.7175.2-173.40000109.6V677S618-V677 WeakPolarHBondContact CA-O 3.1Å
619V98.8Very high97.3Very high0 Ų031 Ų310%018%0.176CC..EExtended strand (participates in β ladder)trans-139.2136.6176.456.50000109.2V603 E605 V607 F621 T676 V677 I692V603-V619 HydrophobicContact CG1-CG2 3.85Å; V603-V619 HydrophobicContact CG2-CG2 4.39Å; E605-V619 WeakPolarHBondContact O-CA 3.21Å; E605-V619 WeakPolarHBondContact O-CG2 3.23Å; V607-V619 HydrophobicContact CG1-CB 3.85Å; V607-V619 HydrophobicContact CG1-CG1 4.49Å; V607-V619 HydrophobicContact CG1-CG2 4.47Å; V619-F621 HydrophobicContact CB-CE2 4.25Å; V619-F621 HydrophobicContact CB-CZ 4.36Å; V619-F621 HydrophobicContact CG1-CE2 3.53Å; V619-F621 HydrophobicContact CG1-CZ 3.8Å; V619-F621 HydrophobicContact CG2-CD2 4.42Å; V619-F621 HydrophobicContact CG2-CE1 4.08Å; V619-F621 HydrophobicContact CG2-CE2 3.79Å; V619-F621 HydrophobicContact CG2-CZ 3.59Å; V619-T676 CarbonylContact O-C 3.47Å; V619-T676 WeakPolarHBondContact O-CA 3.08Å; V619-V677 HydrophobicContact CG1-CB 4.04Å; V619-V677 PolarHBondContact N-O 3.22Å; V619-V677 PolarHBondContact O-N 3.14Å; V619-I692 HydrophobicContact CG1-CB 3.89Å; V619-I692 HydrophobicContact CG1-CD1 4.02Å; V619-I692 HydrophobicContact CG1-CG2 3.67Å
620T98.6Very high97Very high3 Ų328.9 Ų28.92%0.01817%0.171CC..EExtended strand (participates in β ladder)trans-116.3130.1-179.5-60.10000110.2V603 L604 E605 N674 A675 T676V603-T620 CarbonylContact C-O 3.55Å; L604-T620 HydrophobicContact CB-CG2 4.24Å; L604-T620 HydrophobicContact CD1-CG2 4.29Å; L604-T620 PolarHBondContact N-O 3.21Å; E605-T620 PolarHBondContact N-O 3.32Å; E605-T620 PolarHBondContact O-N 2.85Å; E605-T620 PolarHBondContact OE2-OG1 3.03Å; T620-N674 HydrophobicContact CG2-CB 3.9Å; T620-A675 CarbonylContact C-O 3.52Å; T620-A675 WeakPolarHBondContact CA-O 3.34Å; T620-T676 PolarHBondContact OG1-OG1 2.73Å
621F98.6Very high96.6Very high0 Ų029.7 Ų29.70%017%0.174CC..EExtended strand (participates in β ladder)trans-114.2153179.7-55.1-90.5000111.9G601 D602 V603 V619 A623 N674 A675 V677 H694G601-F621 WeakPolarHBondContact O-CD1 3.24Å; D602-F621 CarbonylContact O-C 3Å; D602-F621 VanDerWaalsContact O-CA 3.31Å; D602-F621 WeakPolarHBondContact O-CA 3.45Å; V603-F621 HydrophobicContact CG2-CD1 3.82Å; V603-F621 HydrophobicContact CG2-CE1 3.64Å; V619-F621 HydrophobicContact CB-CE2 4.25Å; V619-F621 HydrophobicContact CB-CZ 4.36Å; V619-F621 HydrophobicContact CG1-CE2 3.53Å; V619-F621 HydrophobicContact CG1-CZ 3.8Å; V619-F621 HydrophobicContact CG2-CD2 4.42Å; V619-F621 HydrophobicContact CG2-CE1 4.08Å; V619-F621 HydrophobicContact CG2-CE2 3.79Å; V619-F621 HydrophobicContact CG2-CZ 3.59Å; F621-A623 PolarHBondContact O-N 2.86Å; F621-N674 VanDerWaalsContact O-CA 3.29Å; F621-N674 WeakPolarHBondContact O-CA 3.2Å; F621-A675 PolarHBondContact N-O 2.92Å; F621-A675 PolarHBondContact O-N 3.2Å; F621-V677 HydrophobicContact CD2-CG2 4.39Å; F621-V677 HydrophobicContact CE2-CG2 4.04Å; F621-H694 HydrophobicContact CD1-CB 4.35Å; F621-H694 HydrophobicContact CD2-CB 3.55Å; F621-H694 HydrophobicContact CE1-CB 4.35Å; F621-H694 HydrophobicContact CE2-CB 3.55Å; F621-H694 HydrophobicContact CG-CB 3.97Å; F621-H694 HydrophobicContact CZ-CB 3.97Å
622V98.4Very high96.2Very high1 Ų129.4 Ų29.41%0.00617%0.173CC..EExtended strand (participates in β ladder)trans-67123161.9-179.70000108.6K594 P595 S599 F600 G601 D602 L604K594-V622 HydrophobicContact CB-CG1 3.86Å; P595-V622 HydrophobicContact CG-CG2 4.26Å; S599-V622 WeakPolarHBondContact O-CB 3.4Å; F600-V622 HydrophobicContact CD1-CG1 4Å; F600-V622 HydrophobicContact CE1-CG1 4.43Å; G601-V622 PolarHBondContact N-O 3.32Å; D602-V622 HydrophobicContact CB-CG2 4.24Å; D602-V622 PolarHBondContact O-N 2.81Å; L604-V622 HydrophobicContact CD1-CG2 3.96Å; L604-V622 HydrophobicContact CD2-CG2 3.58Å; L604-V622 HydrophobicContact CG-CG2 3.71Å
623A97.9Very high96.1Very high1 Ų126.6 Ų26.61%0.00816%0.163CC..EExtended strand (participates in β ladder)trans-132.3148.7-17000000114.9F621 N673 A675 Y711F621-A623 PolarHBondContact O-N 2.86Å; A623-N673 PolarHBondContact N-O 3.48Å; A623-N673 CarbonylContact O-C 3.06Å; A623-N673 WeakPolarHBondContact O-CB 3.49Å; A623-N673 VanDerWaalsContact O-O 3.07Å; A623-A675 HydrophobicContact CB-CB 3.55Å; A623-Y711 WeakPolarHBondContact CA-OH 3.4Å; A623-Y711 VanDerWaalsContact CB-OH 3.29Å; A623-Y711 WeakPolarHBondContact CB-OH 3.45Å
624G97.6Very high95.6Very high3 Ų328.2 Ų28.23%0.03117%0.173CC..  trans-80.1168163.400000112.1P626 W665 H697 Y711G624-P626 WeakPolarHBondContact O-CD 3.29Å; G624-W665 PolarHBondContact O-NE1 2.89Å; G624-H697 WeakPolarHBondContact CA-O 3.4Å; G624-Y711 PolarHBondContact N-OH 3.24Å
625N97.1Very high95.6Very high6 Ų630.6 Ų30.63%0.03217%0.169CC..  trans-70.7125.6173.1-173.1-38.9000111.2E62 D592 R627 H628 W665E62-N625 PolarHBondContact OE2-ND2 2.89Å; D592-N625 PolarHBondContact OD1-N 2.95Å; D592-N625 VanDerWaalsContact OD1-N 3.09Å; N625-R627 PolarHBondContact O-N 3.29Å; N625-R627 VanDerWaalsContact OD1-CB 3.3Å; N625-R627 WeakPolarHBondContact OD1-CB 3.24Å; N625-R627 WeakPolarHBondContact OD1-CG 3.28Å; N625-R627 PolarHBondContact OD1-N 3.04Å; N625-H628 PolarHBondContact O-CD2 3.1Å; N625-H628 VanDerWaalsContact O-CD2 3.27Å; N625-H628 PolarHBondContact O-N 3.34Å; N625-W665 HydrophobicContact CB-CZ2 4.01Å
626P97.1Very high95.6Very high6 Ų630.2 Ų30.24%0.03917%0.168CC..G310 helixtrans-53-24.9179.4-31.836.2000115.1P60 A61 G624 H628 S629 F637 F663 W665P60-P626 HydrophobicContact CG-CB 3.83Å; P60-P626 HydrophobicContact CG-CG 4.46Å; A61-P626 HydrophobicContact CB-CB 3.85Å; A61-P626 HydrophobicContact CB-CG 3.8Å; G624-P626 WeakPolarHBondContact O-CD 3.29Å; P626-H628 PolarHBondContact O-N 3.03Å; P626-H628 VanDerWaalsContact O-N 3.14Å; P626-S629 WeakPolarHBondContact O-CB 3.47Å; P626-S629 PolarHBondContact O-N 3.06Å; P626-S629 PolarHBondContact O-OG 2.8Å; P626-F637 HydrophobicContact CB-CE1 4.06Å; P626-F637 HydrophobicContact CB-CZ 3.78Å; P626-F663 HydrophobicContact CG-CE1 4.08Å; P626-F663 HydrophobicContact CG-CZ 4.05Å; P626-W665 VanDerWaalsContact CD-CG 3.48Å; P626-W665 VanDerWaalsContact CD-NE1 3.31Å; P626-W665 HydrophobicContact CG-CB 3.96Å; P626-W665 HydrophobicContact CG-CD2 4.37Å; P626-W665 HydrophobicContact CG-CG 3.74Å
627R95.6Very high95.6Very high59 Ų5926.6 Ų26.622%0.22315%0.149CC..G310 helixtrans-61.1-16.9174.8-67.3173.165.1-170.33114P59 A61 E62 A587 A589 N625 S629P59-R627 HydrophobicContact CB-CG 4.18Å; A61-R627 HydrophobicContact CB-CG 4.31Å; A61-R627 VanDerWaalsContact O-CD 3.23Å; A61-R627 WeakPolarHBondContact O-CD 3.38Å; A61-R627 WeakPolarHBondContact O-CG 3.28Å; E62-R627 IonicContact OE2-NH1 3.95Å; E62-R627 PolarHBondContact OE2-NH1 3.47Å; A587-R627 PolarHBondContact O-NH1 2.75Å; A587-R627 PolarHBondContact O-NH2 3Å; A589-R627 HydrophobicContact CB-CB 4.1Å; N625-R627 PolarHBondContact O-N 3.29Å; N625-R627 VanDerWaalsContact OD1-CB 3.3Å; N625-R627 WeakPolarHBondContact OD1-CB 3.24Å; N625-R627 WeakPolarHBondContact OD1-CG 3.28Å; N625-R627 PolarHBondContact OD1-N 3.04Å; R627-S629 VanDerWaalsContact C-N 3.34Å
628H96.3Very high95.6Very high14 Ų1426.6 Ų26.67%0.06515%0.149CC..G310 helixtrans-82.4-12.4176.2-57.3-49.4000113.3A589 A590 D592 N625 P626 G630 H697 K699 I708A589-H628 WeakPolarHBondContact CB-CE1 3.41Å; A590-H628 PolarHBondContact O-CE1 3.01Å; A590-H628 PolarHBondContact O-NE2 2.85Å; D592-H628 IonicContact OD1-NE2 3.67Å; D592-H628 IonicContact OD2-CD2 3.44Å; D592-H628 PolarHBondContact OD2-CD2 3.22Å; D592-H628 IonicContact OD2-NE2 3.57Å; D592-H628 PolarHBondContact OD2-NE2 3.04Å; N625-H628 PolarHBondContact O-CD2 3.1Å; N625-H628 VanDerWaalsContact O-CD2 3.27Å; N625-H628 PolarHBondContact O-N 3.34Å; P626-H628 PolarHBondContact O-N 3.03Å; P626-H628 VanDerWaalsContact O-N 3.14Å; H628-G630 PolarHBondContact O-N 2.73Å; H628-H697 HydrophobicContact CB-CB 4.15Å; H628-K699 WeakPolarHBondContact CE1-CB 3.41Å; H628-K699 VanDerWaalsContact CE1-CD 3.42Å; H628-K699 WeakPolarHBondContact CE1-CD 3.34Å; H628-K699 WeakPolarHBondContact NE2-CB 3.34Å; H628-I708 HydrophobicContact CB-CD1 4.33Å; H628-I708 HydrophobicContact CB-CG2 4.16Å; H628-I708 WeakPolarHBondContact O-CG2 3.38Å
629S94.2Very high95.6Very high12 Ų1225 Ų258%0.08414%0.138CC..G310 helixtrans-77.4-3.2-175.2-51.60000114.1P626 R627 I632 H697P626-S629 WeakPolarHBondContact O-CB 3.47Å; P626-S629 PolarHBondContact O-N 3.06Å; P626-S629 PolarHBondContact O-OG 2.8Å; R627-S629 VanDerWaalsContact C-N 3.34Å; S629-I632 WeakPolarHBondContact O-CG2 3.28Å; S629-H697 WeakPolarHBondContact CA-ND1 3.41Å; S629-H697 VanDerWaalsContact CB-ND1 3.34Å; S629-H697 WeakPolarHBondContact CB-ND1 3.38Å; S629-H697 PolarHBondContact OG-ND1 3.05Å
630G89.9Confident95.6Very high50 Ų5025 Ų2552%0.51514%0.138SC..  trans65.2-137.817900000112.7H628 I632H628-G630 PolarHBondContact O-N 2.73Å; G630-I632 PolarHBondContact O-N 2.88Å
631D90.1Very high95.6Very high64 Ų6425.4 Ų25.434%0.34214%0.139SC..  trans-83.7101.3175.1-171.4-4.2000109.9R633D631-R633 VanDerWaalsContact CG-NE 3.33Å; D631-R633 WeakPolarHBondContact OD1-CB 3.23Å; D631-R633 WeakPolarHBondContact OD1-CD 3.39Å; D631-R633 WeakPolarHBondContact OD1-CG 3.12Å; D631-R633 IonicContact OD1-CZ 3.3Å; D631-R633 PolarHBondContact OD1-N 2.92Å; D631-R633 IonicContact OD1-NE 3.58Å; D631-R633 PolarHBondContact OD1-NE 3.37Å; D631-R633 IonicContact OD1-NH2 2.69Å; D631-R633 IonicContact OD2-CZ 3.19Å; D631-R633 VanDerWaalsContact OD2-CZ 3.26Å; D631-R633 IonicContact OD2-NE 3.71Å; D631-R633 PolarHBondContact OD2-NE 3.11Å; D631-R633 IonicContact OD2-NH2 2.78Å; D631-R633 PolarHBondContact OD2-NH2 3.34Å
632I89.6Confident95.6Very high10 Ų1026.5 Ų26.55%0.05115%0.145CC..  trans-96.915.8-176.956.4168.1000112.8R81 S629 G630 D634 Q635 F637R81-I632 PolarHBondContact NH1-O 2.78Å; S629-I632 WeakPolarHBondContact O-CG2 3.28Å; G630-I632 PolarHBondContact O-N 2.88Å; I632-D634 PolarHBondContact O-N 3.15Å; I632-Q635 PolarHBondContact O-N 2.7Å; I632-Q635 VanDerWaalsContact O-N 3.16Å; I632-F637 HydrophobicContact CD1-CD2 4.12Å; I632-F637 HydrophobicContact CD1-CE2 3.15Å; I632-F637 HydrophobicContact CD1-CZ 3.63Å; I632-F637 HydrophobicContact CG2-CZ 4.28Å
633R93.1Very high95.5Very high37 Ų3729.9 Ų29.914%0.1416%0.158CC..THydrogen-bonded Turntrans-59.9138.5175.6-70.4178.4-59137.37.1109.9D55 P165 N168 G169 D631 Q635D55-R633 HydrophobicContact CB-CB 4.03Å; D55-R633 HydrophobicContact CB-CG 4.06Å; D55-R633 WeakPolarHBondContact O-CD 3.14Å; D55-R633 WeakPolarHBondContact OD2-CA 3.46Å; P165-R633 HydrophobicContact CB-CG 4.24Å; P165-R633 WeakPolarHBondContact O-CD 3.35Å; N168-R633 VanDerWaalsContact CB-NH2 3.26Å; N168-R633 PolarHBondContact O-NH1 3.01Å; N168-R633 VanDerWaalsContact O-NH1 3.16Å; G169-R633 VanDerWaalsContact N-NH1 3.12Å; D631-R633 VanDerWaalsContact CG-NE 3.33Å; D631-R633 WeakPolarHBondContact OD1-CB 3.23Å; D631-R633 WeakPolarHBondContact OD1-CD 3.39Å; D631-R633 WeakPolarHBondContact OD1-CG 3.12Å; D631-R633 IonicContact OD1-CZ 3.3Å; D631-R633 PolarHBondContact OD1-N 2.92Å; D631-R633 IonicContact OD1-NE 3.58Å; D631-R633 PolarHBondContact OD1-NE 3.37Å; D631-R633 IonicContact OD1-NH2 2.69Å; D631-R633 IonicContact OD2-CZ 3.19Å; D631-R633 VanDerWaalsContact OD2-CZ 3.26Å; D631-R633 IonicContact OD2-NE 3.71Å; D631-R633 PolarHBondContact OD2-NE 3.11Å; D631-R633 IonicContact OD2-NH2 2.78Å; D631-R633 PolarHBondContact OD2-NH2 3.34Å; R633-Q635 PolarHBondContact O-N 2.84Å; R633-Q635 VanDerWaalsContact O-N 3.09Å
634D87.9Confident95.4Very high100 Ų10031.5 Ų31.554%0.53517%0.167SC..THydrogen-bonded Turntrans61.312.2-177.2-41.9-61000114.5K172 I632K172-D634 IonicContact NZ-OD1 3.3Å; K172-D634 IonicContact NZ-OD2 2.69Å; K172-D634 PolarHBondContact NZ-OD2 3.23Å; I632-D634 PolarHBondContact O-N 3.15Å
635Q94.3Very high95.1Very high110 Ų11037.6 Ų37.651%0.51420%0.199SC..  trans-114.2173.1168.3-61.5178.74400109.4R81 I632 R633R81-Q635 PolarHBondContact NH2-O 2.73Å; I632-Q635 PolarHBondContact O-N 2.7Å; I632-Q635 VanDerWaalsContact O-N 3.16Å; R633-Q635 PolarHBondContact O-N 2.84Å; R633-Q635 VanDerWaalsContact O-N 3.09Å
636T97.2Very high94.9Very high34 Ų3448.1 Ų48.121%0.20924%0.238CC..  trans-137.6146.1-178.5-164.60000112.5V638 T639 D656 F695T636-V638 VanDerWaalsContact C-N 3.34Å; T636-V638 WeakPolarHBondContact CG2-O 3.38Å; T636-V638 PolarHBondContact OG1-N 2.78Å; T636-V638 PolarHBondContact OG1-O 2.95Å; T636-T639 HydrophobicContact CG2-CG2 3.67Å; T636-D656 WeakPolarHBondContact OG1-CB 3.48Å; T636-D656 PolarHBondContact OG1-N 3.43Å; T636-D656 VanDerWaalsContact OG1-N 3.09Å; T636-D656 PolarHBondContact OG1-OD1 2.91Å; T636-D656 PolarHBondContact OG1-OD2 2.91Å; T636-F695 HydrophobicContact CG2-CD2 4.24Å; T636-F695 HydrophobicContact CG2-CE2 4.28Å; T636-F695 WeakPolarHBondContact O-CD2 3.24Å
637F98.3Very high94.8Very high7 Ų751 Ų513%0.03126%0.255CS..SBendtrans-81.3-17.8170.3-74.6-75.9000112.6P60 I78 P626 I632 D656 F663 H694 F695P60-F637 HydrophobicContact CG-CD2 4.42Å; P60-F637 HydrophobicContact CG-CE2 3.65Å; P60-F637 HydrophobicContact CG-CZ 4.16Å; I78-F637 HydrophobicContact CD1-CD2 3.81Å; I78-F637 HydrophobicContact CD1-CE2 4.03Å; P626-F637 HydrophobicContact CB-CE1 4.06Å; P626-F637 HydrophobicContact CB-CZ 3.78Å; I632-F637 HydrophobicContact CD1-CD2 4.12Å; I632-F637 HydrophobicContact CD1-CE2 3.15Å; I632-F637 HydrophobicContact CD1-CZ 3.63Å; I632-F637 HydrophobicContact CG2-CZ 4.28Å; F637-D656 PolarHBondContact N-OD2 2.89Å; F637-F663 HydrophobicContact CB-CD1 4.15Å; F637-F663 HydrophobicContact CB-CD2 4.18Å; F637-F663 HydrophobicContact CB-CE1 4.19Å; F637-F663 HydrophobicContact CB-CE2 4.2Å; F637-F663 HydrophobicContact CB-CG 4.15Å; F637-F663 HydrophobicContact CB-CZ 4.21Å; F637-F663 HydrophobicContact CD1-CE1 4.19Å; F637-F663 HydrophobicContact CD1-CZ 4.02Å; F637-F663 HydrophobicContact CD2-CD1 4.25Å; F637-F663 HydrophobicContact CD2-CE1 4.05Å; F637-F663 HydrophobicContact CE2-CE1 4.46Å; F637-F663 HydrophobicContact CG-CD1 4.23Å; F637-F663 AromaticContact CG-CE1 3.9Å; F637-F663 HydrophobicContact CG-CE1 3.9Å; F637-F663 HydrophobicContact CG-CZ 4.07Å; F637-H694 WeakPolarHBondContact O-CA 3.49Å; F637-H694 PolarHBondContact O-ND1 2.86Å; F637-F695 VanDerWaalsContact CD1-O 3.26Å; F637-F695 WeakPolarHBondContact CD1-O 3.22Å; F637-F695 PolarHBondContact O-N 2.03Å
638V97.9Very high94.8Very high0 Ų055.1 Ų55.10%028%0.277CS..EExtended strand (participates in β ladder)trans-142.8138-169.8173.40000110.2T636 N655 D656 F663 V677 R693T636-V638 VanDerWaalsContact C-N 3.34Å; T636-V638 WeakPolarHBondContact CG2-O 3.38Å; T636-V638 PolarHBondContact OG1-N 2.78Å; T636-V638 PolarHBondContact OG1-O 2.95Å; V638-N655 VanDerWaalsContact O-CA 3.3Å; V638-N655 WeakPolarHBondContact O-CA 3.45Å; V638-D656 HydrophobicContact CB-CB 4.2Å; V638-D656 PolarHBondContact O-N 2.86Å; V638-F663 HydrophobicContact CG2-CB 3.88Å; V638-F663 HydrophobicContact CG2-CD2 3.88Å; V638-F663 HydrophobicContact CG2-CG 4.19Å; V638-V677 HydrophobicContact CB-CG1 4.31Å; V638-V677 HydrophobicContact CG1-CG1 3.42Å; V638-V677 VanDerWaalsContact CG1-CG1 3.42Å; V638-V677 HydrophobicContact CG1-CG2 4.44Å; V638-V677 HydrophobicContact CG2-CB 4.35Å; V638-V677 HydrophobicContact CG2-CG1 3.88Å; V638-V677 HydrophobicContact CG2-CG2 3.52Å; V638-R693 WeakPolarHBondContact CA-O 3.26Å
639T98.7Very high94.8Very high9 Ų959.2 Ų59.26%0.05530%0.3CS..EExtended strand (participates in β ladder)trans-130.7143.3160.350.30000110.3T636 V652 Y654 I692 R693 F695T636-T639 HydrophobicContact CG2-CG2 3.67Å; T639-V652 HydrophobicContact CG2-CG1 3.72Å; T639-V652 HydrophobicContact CG2-CG2 4Å; T639-Y654 CarbonylContact C-O 3.51Å; T639-Y654 VanDerWaalsContact CA-O 3.31Å; T639-Y654 WeakPolarHBondContact CA-O 3.29Å; T639-I692 WeakPolarHBondContact O-CA 3.31Å; T639-R693 PolarHBondContact N-O 3.06Å; T639-R693 PolarHBondContact O-N 3.16Å; T639-F695 HydrophobicContact CG2-CE2 3.88Å; T639-F695 WeakPolarHBondContact OG1-CE2 3.32Å
640V98.8Very high95Very high0 Ų061.9 Ų61.90%031%0.308CS..EExtended strand (participates in β ladder)trans-104.3124.4160.7-175.70000106.1V653 Y654 T661 W679 Y690 I692V640-V653 HydrophobicContact CB-CG2 4.42Å; V640-V653 HydrophobicContact CG1-CG2 4.24Å; V640-V653 VanDerWaalsContact O-CG2 3.27Å; V640-V653 WeakPolarHBondContact O-CG2 3.3Å; V640-V653 PolarHBondContact O-N 2.77Å; V640-Y654 HydrophobicContact CB-CD2 3.96Å; V640-Y654 HydrophobicContact CB-CG 4.42Å; V640-Y654 HydrophobicContact CG1-CD2 4.14Å; V640-Y654 HydrophobicContact CG2-CD2 4.38Å; V640-Y654 PolarHBondContact N-O 3.03Å; V640-Y654 PolarHBondContact O-N 3Å; V640-T661 HydrophobicContact CG2-CG2 3.97Å; V640-W679 HydrophobicContact CG1-CD2 3.77Å; V640-W679 HydrophobicContact CG1-CE3 3.62Å; V640-W679 HydrophobicContact CG1-CG 4.42Å; V640-W679 HydrophobicContact CG1-CH2 4.07Å; V640-W679 HydrophobicContact CG1-CZ2 4.21Å; V640-W679 HydrophobicContact CG1-CZ3 3.76Å; V640-W679 HydrophobicContact CG2-CB 4.07Å; V640-W679 HydrophobicContact CG2-CD2 4.1Å; V640-W679 HydrophobicContact CG2-CG 3.85Å; V640-Y690 HydrophobicContact CG1-CD1 3.99Å; V640-I692 HydrophobicContact CG2-CG1 4.28Å
641E98.7Very high95.3Very high10 Ų1064.2 Ų64.25%0.04731%0.306CS..EExtended strand (participates in β ladder)trans-117.3138.6-175.9-60.8177.6175.500109.8W650 E651 V652 Y690 R691 R693E641-W650 HydrophobicContact CB-CB 4.24Å; E641-W650 HydrophobicContact CB-CD2 4.47Å; E641-W650 HydrophobicContact CB-CE3 3.75Å; E641-W650 WeakPolarHBondContact O-CZ3 3.36Å; E641-W650 WeakPolarHBondContact OE2-CB 3.22Å; E641-E651 CarbonylContact C-O 3.57Å; E641-E651 WeakPolarHBondContact CA-O 3.31Å; E641-V652 HydrophobicContact CG-CG2 4.01Å; E641-Y690 CarbonylContact O-C 3.6Å; E641-Y690 WeakPolarHBondContact O-CA 3.44Å; E641-Y690 WeakPolarHBondContact O-CD1 3.27Å; E641-R691 HydrophobicContact CB-CG 4.13Å; E641-R691 PolarHBondContact N-O 2.91Å; E641-R691 PolarHBondContact O-N 2.65Å; E641-R691 IonicContact OE2-CZ 3.43Å; E641-R691 IonicContact OE2-NE 3.88Å; E641-R691 PolarHBondContact OE2-NE 3Å; E641-R691 IonicContact OE2-NH2 2.6Å; E641-R691 PolarHBondContact OE2-NH2 3.3Å; E641-R693 VanDerWaalsContact CD-CD 3.5Å; E641-R693 WeakPolarHBondContact OE1-CD 3.46Å; E641-R693 IonicContact OE1-NH1 3.37Å; E641-R693 PolarHBondContact OE1-NH1 3.27Å; E641-R693 WeakPolarHBondContact OE2-CD 3.39Å
642I98.2Very high95.7Very high24 Ų2463.8 Ų63.812%0.12331%0.305CS..EExtended strand (participates in β ladder)trans-103.1142.1171.1-165.4179000109.5W650 E651 V653 P686 S689 Y690I642-W650 WeakPolarHBondContact O-CA 3.4Å; I642-E651 HydrophobicContact CG2-CB 4.13Å; I642-E651 PolarHBondContact N-O 3.26Å; I642-E651 PolarHBondContact O-N 3.14Å; I642-V653 HydrophobicContact CB-CG1 4.2Å; I642-V653 HydrophobicContact CB-CG2 4.47Å; I642-V653 HydrophobicContact CG2-CG1 3.54Å; I642-P686 HydrophobicContact CD1-CB 4.11Å; I642-S689 WeakPolarHBondContact CA-O 3.36Å; I642-Y690 HydrophobicContact CB-CD1 3.96Å; I642-Y690 HydrophobicContact CB-CE1 3.61Å; I642-Y690 HydrophobicContact CD1-CE1 4.04Å; I642-Y690 HydrophobicContact CD1-CE2 4.2Å; I642-Y690 WeakPolarHBondContact CD1-OH 3.45Å; I642-Y690 HydrophobicContact CG1-CD1 4.21Å; I642-Y690 HydrophobicContact CG1-CE1 3.76Å; I642-Y690 HydrophobicContact CG1-CE2 4.13Å
643Y98.2Very high96.1Very high72 Ų7265.5 Ų65.528%0.28232%0.316SS..EExtended strand (participates in β ladder)trans-87.5121.2174.6-171-108000111.1N645 E648 W650 S689Y643-N645 WeakPolarHBondContact CD1-OD1 3.37Å; Y643-N645 WeakPolarHBondContact CE1-OD1 3.46Å; Y643-E648 WeakPolarHBondContact OH-CA 3.38Å; Y643-W650 AromaticContact CD2-CD2 4Å; Y643-W650 HydrophobicContact CD2-CD2 4Å; Y643-W650 AromaticContact CD2-CE2 3.7Å; Y643-W650 HydrophobicContact CD2-CG 4.24Å; Y643-W650 HydrophobicContact CD2-CZ2 4.09Å; Y643-W650 AromaticContact CD2-NE1 3.74Å; Y643-W650 HydrophobicContact CG-CZ2 4.4Å; Y643-S689 PolarHBondContact N-O 3.15Å
644D95.1Very high96.3Very high35 Ų3565.3 Ų65.319%0.18732%0.315CS..EExtended strand (participates in β ladder)trans-93.1107.4171.9176.916.9000110.6R646 T647 E648 N649D644-R646 PolarHBondContact O-N 2.96Å; D644-R646 VanDerWaalsContact O-N 3.14Å; D644-R646 VanDerWaalsContact OD1-CB 3.28Å; D644-R646 WeakPolarHBondContact OD1-CB 3.29Å; D644-R646 PolarHBondContact OD1-N 2.87Å; D644-T647 WeakPolarHBondContact CB-OG1 3.46Å; D644-T647 PolarHBondContact O-N 2.89Å; D644-T647 VanDerWaalsContact OD2-CG2 3.24Å; D644-T647 WeakPolarHBondContact OD2-CG2 3.2Å; D644-T647 PolarHBondContact OD2-N 3.16Å; D644-T647 PolarHBondContact OD2-OG1 2.95Å; D644-E648 WeakPolarHBondContact O-CA 3.28Å; D644-E648 PolarHBondContact O-N 2.6Å; D644-N649 PolarHBondContact N-O 3.4Å
645N91.6Very high96.8Very high131 Ų13161.3 Ų61.370%0.70129%0.294SS*.THydrogen-bonded Turntrans-61.1-20177.1-72-44.9000113.9Y643Y643-N645 WeakPolarHBondContact CD1-OD1 3.37Å; Y643-N645 WeakPolarHBondContact CE1-OD1 3.46Å
646R93.2Very high97Very high226 Ų22656.2 Ų56.285%0.85327%0.27SS*.THydrogen-bonded Turntrans-79.1-36.3179.6-64.516339.4123.72.3112.2D644D644-R646 PolarHBondContact O-N 2.96Å; D644-R646 VanDerWaalsContact O-N 3.14Å; D644-R646 VanDerWaalsContact OD1-CB 3.28Å; D644-R646 WeakPolarHBondContact OD1-CB 3.29Å; D644-R646 PolarHBondContact OD1-N 2.87Å
647T94.4Very high97Very high66 Ų6654.7 Ų54.741%0.40526%0.261SS..THydrogen-bonded Turntrans-103-8.3-177.257.30000112.9D644 N649D644-T647 WeakPolarHBondContact CB-OG1 3.46Å; D644-T647 PolarHBondContact O-N 2.89Å; D644-T647 VanDerWaalsContact OD2-CG2 3.24Å; D644-T647 WeakPolarHBondContact OD2-CG2 3.2Å; D644-T647 PolarHBondContact OD2-N 3.16Å; D644-T647 PolarHBondContact OD2-OG1 2.95Å; T647-N649 PolarHBondContact O-N 2.92Å; T647-N649 PolarHBondContact O-ND2 2.86Å
648E94.6Very high97Very high146 Ų14654.3 Ų54.368%0.68226%0.259SS*.THydrogen-bonded Turntrans56.531.2-174.6-58.5-176161.300112.7Y643 D644Y643-E648 WeakPolarHBondContact OH-CA 3.38Å; D644-E648 WeakPolarHBondContact O-CA 3.28Å; D644-E648 PolarHBondContact O-N 2.6Å
649N96.9Very high97Very high100 Ų10055.5 Ų55.554%0.53526%0.264SS..EExtended strand (participates in β ladder)trans-126.3159.1-175.6-72-47.7000112.4D644 T647D644-N649 PolarHBondContact N-O 3.4Å; T647-N649 PolarHBondContact O-N 2.92Å; T647-N649 PolarHBondContact O-ND2 2.86Å
650W97.9Very high97Very high68 Ų6856.8 Ų56.826%0.25827%0.269SS..EExtended strand (participates in β ladder)trans-92.9128.1171.3-7192.7000110.2E641 I642 Y643 R691 V717E641-W650 HydrophobicContact CB-CB 4.24Å; E641-W650 HydrophobicContact CB-CD2 4.47Å; E641-W650 HydrophobicContact CB-CE3 3.75Å; E641-W650 WeakPolarHBondContact O-CZ3 3.36Å; E641-W650 WeakPolarHBondContact OE2-CB 3.22Å; I642-W650 WeakPolarHBondContact O-CA 3.4Å; Y643-W650 AromaticContact CD2-CD2 4Å; Y643-W650 HydrophobicContact CD2-CD2 4Å; Y643-W650 AromaticContact CD2-CE2 3.7Å; Y643-W650 HydrophobicContact CD2-CG 4.24Å; Y643-W650 HydrophobicContact CD2-CZ2 4.09Å; Y643-W650 AromaticContact CD2-NE1 3.74Å; Y643-W650 HydrophobicContact CG-CZ2 4.4Å; W650-R691 HydrophobicContact CD2-CG 4.17Å; W650-R691 HydrophobicContact CE3-CG 3.77Å; W650-R691 HydrophobicContact CH2-CB 3.97Å; W650-R691 HydrophobicContact CH2-CG 3.88Å; W650-R691 HydrophobicContact CZ2-CG 4.28Å; W650-R691 HydrophobicContact CZ3-CB 4Å; W650-R691 HydrophobicContact CZ3-CG 3.62Å; W650-V717 HydrophobicContact CH2-CB 4.46Å; W650-V717 HydrophobicContact CH2-CG1 4.02Å; W650-V717 HydrophobicContact CH2-CG2 3.73Å; W650-V717 HydrophobicContact CZ2-CG2 3.67Å
651E97.4Very high97Very high100 Ų10056.8 Ų56.847%0.46727%0.269SS..EExtended strand (participates in β ladder)trans-111.1131.3177.1-63.6-172.5161.900110.1E641 I642 V653E641-E651 CarbonylContact C-O 3.57Å; E641-E651 WeakPolarHBondContact CA-O 3.31Å; I642-E651 HydrophobicContact CG2-CB 4.13Å; I642-E651 PolarHBondContact N-O 3.26Å; I642-E651 PolarHBondContact O-N 3.14Å; E651-V653 PolarHBondContact O-N 3.14Å
652V97.9Very high97Very high55 Ų5558 Ų5833%0.33327%0.274SS..EExtended strand (participates in β ladder)trans-73.5124176-179.40000108.7L278 T639 E641 Y654L278-V652 HydrophobicContact CD1-CB 4.1Å; L278-V652 HydrophobicContact CD1-CG1 3.69Å; L278-V652 HydrophobicContact CD2-CG1 4.15Å; T639-V652 HydrophobicContact CG2-CG1 3.72Å; T639-V652 HydrophobicContact CG2-CG2 4Å; E641-V652 HydrophobicContact CG-CG2 4.01Å; V652-Y654 WeakPolarHBondContact CG1-O 3.34Å
653V97.4Very high97Very high45 Ų4557 Ų5727%0.27327%0.268SS..EExtended strand (participates in β ladder)trans-114.2-21.8178-70.60000113.2V640 I642 E651 Y690V640-V653 HydrophobicContact CB-CG2 4.42Å; V640-V653 HydrophobicContact CG1-CG2 4.24Å; V640-V653 VanDerWaalsContact O-CG2 3.27Å; V640-V653 WeakPolarHBondContact O-CG2 3.3Å; V640-V653 PolarHBondContact O-N 2.77Å; I642-V653 HydrophobicContact CB-CG1 4.2Å; I642-V653 HydrophobicContact CB-CG2 4.47Å; I642-V653 HydrophobicContact CG2-CG1 3.54Å; E651-V653 PolarHBondContact O-N 3.14Å; V653-Y690 HydrophobicContact CG2-CD1 4.46Å; V653-Y690 HydrophobicContact CG2-CE1 4Å
654Y98.4Very high97Very high34 Ų3455.7 Ų55.713%0.13327%0.265CS..EExtended strand (participates in β ladder)trans-140.8151.2171.6-55.3-82.5000110.4T639 V640 V652 S658 E660 W679 P682T639-Y654 CarbonylContact C-O 3.51Å; T639-Y654 VanDerWaalsContact CA-O 3.31Å; T639-Y654 WeakPolarHBondContact CA-O 3.29Å; V640-Y654 HydrophobicContact CB-CD2 3.96Å; V640-Y654 HydrophobicContact CB-CG 4.42Å; V640-Y654 HydrophobicContact CG1-CD2 4.14Å; V640-Y654 HydrophobicContact CG2-CD2 4.38Å; V640-Y654 PolarHBondContact N-O 3.03Å; V640-Y654 PolarHBondContact O-N 3Å; V652-Y654 WeakPolarHBondContact CG1-O 3.34Å; Y654-S658 WeakPolarHBondContact CA-OG 3.47Å; Y654-E660 HydrophobicContact CD1-CB 4.26Å; Y654-E660 HydrophobicContact CD1-CG 4.46Å; Y654-E660 HydrophobicContact CE1-CB 4.27Å; Y654-E660 HydrophobicContact CE1-CG 4.03Å; Y654-W679 AromaticContact CD2-CE2 3.83Å; Y654-W679 AromaticContact CD2-CZ2 4Å; Y654-W679 HydrophobicContact CD2-CZ2 4Å; Y654-W679 AromaticContact CD2-NE1 3.48Å; Y654-W679 AromaticContact CE2-CE2 3.74Å; Y654-W679 AromaticContact CE2-CZ2 3.56Å; Y654-W679 HydrophobicContact CE2-CZ2 3.56Å; Y654-W679 AromaticContact CE2-NE1 3.49Å; Y654-P682 WeakPolarHBondContact OH-CG 3.33Å
655N98.3Very high97.2Very high15 Ų1554.3 Ų54.38%0.0826%0.257CS..EExtended strand (participates in β ladder)trans-132.7178.4176.963.910.1000110.3P279 V638 A657 S658 T661P279-N655 PolarHBondContact O-ND2 2.79Å; P279-N655 VanDerWaalsContact O-ND2 3.12Å; V638-N655 VanDerWaalsContact O-CA 3.3Å; V638-N655 WeakPolarHBondContact O-CA 3.45Å; N655-A657 PolarHBondContact O-N 3.44Å; N655-A657 WeakPolarHBondContact OD1-CA 2.95Å; N655-A657 WeakPolarHBondContact OD1-CB 3.45Å; N655-A657 PolarHBondContact OD1-N 2.88Å; N655-S658 PolarHBondContact N-OG 3.26Å; N655-S658 WeakPolarHBondContact O-CB 3.44Å; N655-S658 PolarHBondContact O-N 3.48Å; N655-S658 PolarHBondContact O-OG 3.03Å; N655-S658 VanDerWaalsContact O-OG 3.12Å; N655-S658 PolarHBondContact OD1-N 2.97Å; N655-S658 VanDerWaalsContact OD1-N 3.08Å; N655-S658 PolarHBondContact OD1-OG 3.15Å; N655-T661 PolarHBondContact O-OG1 2.71Å
656D97.9Very high97.3Very high3 Ų352.3 Ų52.32%0.01625%0.245CC..THydrogen-bonded Turntrans-67.22.4176.270.8-3.5000115.9I78 R81 T636 F637 V638I78-D656 VanDerWaalsContact CG2-O 3.3Å; I78-D656 WeakPolarHBondContact CG2-O 3.42Å; R81-D656 IonicContact CZ-OD1 2.8Å; R81-D656 IonicContact CZ-OD2 3.92Å; R81-D656 IonicContact NE-OD1 3.04Å; R81-D656 PolarHBondContact NE-OD1 2.83Å; R81-D656 VanDerWaalsContact NE-OD1 3.09Å; R81-D656 IonicContact NE-OD2 2.79Å; R81-D656 PolarHBondContact NE-OD2 3.43Å; R81-D656 IonicContact NH2-OD1 2.79Å; R81-D656 IonicContact NH2-OD2 3.33Å; R81-D656 PolarHBondContact NH2-OD2 2.9Å; T636-D656 WeakPolarHBondContact OG1-CB 3.48Å; T636-D656 PolarHBondContact OG1-N 3.43Å; T636-D656 VanDerWaalsContact OG1-N 3.09Å; T636-D656 PolarHBondContact OG1-OD1 2.91Å; T636-D656 PolarHBondContact OG1-OD2 2.91Å; F637-D656 PolarHBondContact N-OD2 2.89Å; V638-D656 HydrophobicContact CB-CB 4.2Å; V638-D656 PolarHBondContact O-N 2.86Å
657A98.1Very high97.3Very high2 Ų248.2 Ų48.22%0.01723%0.234CC..THydrogen-bonded Turntrans-97.3-12.8167.500000112.9R81 Y83 P279 N655R81-A657 HydrophobicContact CB-CB 3.91Å; R81-A657 HydrophobicContact CG-CB 3.72Å; Y83-A657 WeakPolarHBondContact OH-CB 3.48Å; P279-A657 HydrophobicContact CB-CB 3.96Å; N655-A657 PolarHBondContact O-N 3.44Å; N655-A657 WeakPolarHBondContact OD1-CA 2.95Å; N655-A657 WeakPolarHBondContact OD1-CB 3.45Å; N655-A657 PolarHBondContact OD1-N 2.88Å
658S98.4Very high96.9Very high0 Ų046.7 Ų46.70%023%0.231CC..SBendtrans-74.6129.6179.7-52.80000110.6P279 Y654 N655 E660 T661P279-S658 WeakPolarHBondContact CG-OG 3.37Å; Y654-S658 WeakPolarHBondContact CA-OG 3.47Å; N655-S658 PolarHBondContact N-OG 3.26Å; N655-S658 WeakPolarHBondContact O-CB 3.44Å; N655-S658 PolarHBondContact O-N 3.48Å; N655-S658 PolarHBondContact O-OG 3.03Å; N655-S658 VanDerWaalsContact O-OG 3.12Å; N655-S658 PolarHBondContact OD1-N 2.97Å; N655-S658 VanDerWaalsContact OD1-N 3.08Å; N655-S658 PolarHBondContact OD1-OG 3.15Å; S658-E660 PolarHBondContact O-N 3.28Å; S658-E660 VanDerWaalsContact O-N 3.11Å; S658-T661 PolarHBondContact O-N 2.71Å; S658-T661 PolarHBondContact O-OG1 2.89Å
659W97.9Very high96.6Very high24 Ų2444.4 Ų44.49%0.09123%0.232CC..THydrogen-bonded Turntrans-58.3-29.3-177-176.2-94.7000113.4H79 T80 Y264 Y267 F337 T340 R341 T661H79-W659 AromaticContact CE1-CD2 3.62Å; H79-W659 AromaticContact CE1-CE2 3.68Å; H79-W659 AromaticContact CE1-CE3 3.39Å; H79-W659 AromaticContact CE1-CH2 3.38Å; H79-W659 WeakPolarHBondContact CE1-CH2 3.29Å; H79-W659 AromaticContact CE1-CZ2 3.57Å; H79-W659 AromaticContact CE1-CZ3 3.28Å; H79-W659 WeakPolarHBondContact CE1-CZ3 3.11Å; H79-W659 AromaticContact ND1-CZ3 3.97Å; H79-W659 AromaticContact NE2-CD2 3.62Å; H79-W659 AromaticContact NE2-CE2 3.87Å; H79-W659 AromaticContact NE2-CE3 3.69Å; H79-W659 PolarHBondContact NE2-O 2.99Å; T80-W659 HydrophobicContact CG2-CE3 3.68Å; T80-W659 HydrophobicContact CG2-CZ3 4.2Å; Y264-W659 HydrophobicContact CD2-CB 4.4Å; Y264-W659 AromaticContact CD2-CD2 3.36Å; Y264-W659 HydrophobicContact CD2-CD2 3.36Å; Y264-W659 AromaticContact CD2-CE2 3.9Å; Y264-W659 AromaticContact CD2-CE3 3.17Å; Y264-W659 HydrophobicContact CD2-CE3 3.17Å; Y264-W659 AromaticContact CD2-CG 3.93Å; Y264-W659 HydrophobicContact CD2-CG 3.93Å; Y264-W659 HydrophobicContact CD2-CH2 4.03Å; Y264-W659 HydrophobicContact CD2-CZ2 4.22Å; Y264-W659 AromaticContact CD2-CZ3 3.53Å; Y264-W659 HydrophobicContact CD2-CZ3 3.53Å; Y264-W659 HydrophobicContact CE2-CB 3.91Å; Y264-W659 AromaticContact CE2-CD1 3.88Å; Y264-W659 AromaticContact CE2-CD2 3.33Å; Y264-W659 HydrophobicContact CE2-CD2 3.33Å; Y264-W659 AromaticContact CE2-CE2 3.75Å; Y264-W659 AromaticContact CE2-CE3 3.69Å; Y264-W659 HydrophobicContact CE2-CE3 3.69Å; Y264-W659 AromaticContact CE2-CG 3.43Å; Y264-W659 HydrophobicContact CE2-CG 3.43Å; Y264-W659 VanDerWaalsContact CE2-CG 3.43Å; Y264-W659 HydrophobicContact CE2-CZ2 4.41Å; Y264-W659 HydrophobicContact CE2-CZ3 4.34Å; Y264-W659 HydrophobicContact CG-CD2 4.3Å; Y264-W659 AromaticContact CG-CE3 3.96Å; Y264-W659 HydrophobicContact CG-CE3 3.96Å; Y264-W659 HydrophobicContact CG-CH2 4.05Å; Y264-W659 HydrophobicContact CG-CZ2 4.41Å; Y264-W659 AromaticContact CG-CZ3 3.83Å; Y264-W659 HydrophobicContact CG-CZ3 3.83Å; Y267-W659 HydrophobicContact CE1-CB 3.94Å; Y267-W659 PolarHBondContact OH-N 3.43Å; F337-W659 WeakPolarHBondContact O-CZ2 2.98Å; T340-W659 HydrophobicContact CG2-CH2 3.56Å; T340-W659 HydrophobicContact CG2-CZ3 4.33Å; R341-W659 HydrophobicContact CB-CZ2 3.88Å; W659-T661 VanDerWaalsContact C-N 3.26Å; W659-T661 PolarHBondContact O-N 2.98Å
660E98.1Very high96.2Very high36 Ų3644.1 Ų44.117%0.16823%0.23CC..THydrogen-bonded Turntrans-71.9-17.5-179.8-62.771.4-155.300112.7Y267 Y654 S658 F680 P682Y267-E660 PolarHBondContact OH-OE2 3.34Å; Y654-E660 HydrophobicContact CD1-CB 4.26Å; Y654-E660 HydrophobicContact CD1-CG 4.46Å; Y654-E660 HydrophobicContact CE1-CB 4.27Å; Y654-E660 HydrophobicContact CE1-CG 4.03Å; S658-E660 PolarHBondContact O-N 3.28Å; S658-E660 VanDerWaalsContact O-N 3.11Å; E660-F680 WeakPolarHBondContact O-CD2 3.48Å; E660-F680 PolarHBondContact O-N 3.43Å; E660-P682 HydrophobicContact CG-CB 4.49Å; E660-P682 HydrophobicContact CG-CG 4.21Å
661T98.6Very high95.8Very high1 Ų145.3 Ų45.31%0.00623%0.234CC..EExtended strand (participates in β ladder)trans-102.7149.4-179.970.60000111.6V640 N655 S658 W659 E678V640-T661 HydrophobicContact CG2-CG2 3.97Å; N655-T661 PolarHBondContact O-OG1 2.71Å; S658-T661 PolarHBondContact O-N 2.71Å; S658-T661 PolarHBondContact O-OG1 2.89Å; W659-T661 VanDerWaalsContact C-N 3.26Å; W659-T661 PolarHBondContact O-N 2.98Å; T661-E678 CarbonylContact C-O 3.56Å; T661-E678 VanDerWaalsContact CA-O 3.3Å; T661-E678 WeakPolarHBondContact CA-O 3.47Å
662R98.6Very high95.6Very high36 Ų3643 Ų4314%0.13622%0.223CC..EExtended strand (participates in β ladder)trans-134.5123.8168.9-57.7-179.7-177.1165.20.2109.4M256 H664 V677 E678 F680M256-R662 HydrophobicContact CE-CB 4.47Å; M256-R662 HydrophobicContact CE-CG 4.24Å; M256-R662 HydrophobicContact SD-CB 4.12Å; M256-R662 HydrophobicContact SD-CG 4.48Å; R662-H664 WeakPolarHBondContact CB-NE2 3.39Å; R662-V677 WeakPolarHBondContact O-CA 3.41Å; R662-E678 HydrophobicContact CB-CB 4.25Å; R662-E678 PolarHBondContact N-O 3.33Å; R662-E678 IonicContact NH1-OE2 2.73Å; R662-E678 PolarHBondContact O-N 3.08Å; R662-F680 HydrophobicContact CG-CE2 4.05Å; R662-F680 VanDerWaalsContact CZ-CE2 3.5Å
663F98.5Very high95.6Very high2 Ų240.7 Ų40.71%0.00921%0.209CC..EExtended strand (participates in β ladder)trans-100.5111.4173.2168.8-114.1000108.7P60 G77 I78 P626 F637 V638 W665 A675 V677 H694P60-F663 HydrophobicContact CG-CE1 4.36Å; G77-F663 CarbonylContact C-O 3.46Å; G77-F663 WeakPolarHBondContact CA-O 3.42Å; I78-F663 HydrophobicContact CB-CB 4.44Å; I78-F663 HydrophobicContact CB-CD1 4.34Å; I78-F663 HydrophobicContact CG1-CD1 4.25Å; I78-F663 PolarHBondContact N-O 3.31Å; I78-F663 PolarHBondContact O-N 2.86Å; P626-F663 HydrophobicContact CG-CE1 4.08Å; P626-F663 HydrophobicContact CG-CZ 4.05Å; F637-F663 HydrophobicContact CB-CD1 4.15Å; F637-F663 HydrophobicContact CB-CD2 4.18Å; F637-F663 HydrophobicContact CB-CE1 4.19Å; F637-F663 HydrophobicContact CB-CE2 4.2Å; F637-F663 HydrophobicContact CB-CG 4.15Å; F637-F663 HydrophobicContact CB-CZ 4.21Å; F637-F663 HydrophobicContact CD1-CE1 4.19Å; F637-F663 HydrophobicContact CD1-CZ 4.02Å; F637-F663 HydrophobicContact CD2-CD1 4.25Å; F637-F663 HydrophobicContact CD2-CE1 4.05Å; F637-F663 HydrophobicContact CE2-CE1 4.46Å; F637-F663 HydrophobicContact CG-CD1 4.23Å; F637-F663 AromaticContact CG-CE1 3.9Å; F637-F663 HydrophobicContact CG-CE1 3.9Å; F637-F663 HydrophobicContact CG-CZ 4.07Å; V638-F663 HydrophobicContact CG2-CB 3.88Å; V638-F663 HydrophobicContact CG2-CD2 3.88Å; V638-F663 HydrophobicContact CG2-CG 4.19Å; F663-W665 HydrophobicContact CE1-CB 4.4Å; F663-W665 HydrophobicContact CZ-CB 4.29Å; F663-A675 HydrophobicContact CE2-CB 3.73Å; F663-V677 HydrophobicContact CD2-CG2 4.41Å; F663-H694 AromaticContact CE2-CE1 3.49Å; F663-H694 VanDerWaalsContact CE2-CE1 3.49Å; F663-H694 WeakPolarHBondContact CE2-CE1 3.36Å; F663-H694 AromaticContact CE2-ND1 3.87Å
664H98.4Very high95.6Very high45 Ų4540.9 Ų40.921%0.20821%0.209CC..EExtended strand (participates in β ladder)trans-101.3127.7174.9-62.1-91.8000110M256 R662 A675 T676 E678M256-H664 VanDerWaalsContact SD-CE1 3.57Å; R662-H664 WeakPolarHBondContact CB-NE2 3.39Å; H664-A675 CarbonylContact O-C 3.57Å; H664-A675 VanDerWaalsContact O-CA 3.3Å; H664-A675 WeakPolarHBondContact O-CA 3.33Å; H664-T676 WeakPolarHBondContact CB-O 3.5Å; H664-T676 PolarHBondContact N-O 2.77Å; H664-T676 PolarHBondContact O-N 3.34Å; H664-E678 IonicContact NE2-OE2 3.96Å
665W97.9Very high95.5Very high6 Ų639.3 Ų39.32%0.02320%0.203CC..EExtended strand (participates in β ladder)trans-104.7119.3167.3177.474.9000110.3A61 E62 A76 G624 N625 P626 F663 K667 N673A61-W665 HydrophobicContact CB-CD2 3.94Å; A61-W665 HydrophobicContact CB-CE3 3.65Å; A61-W665 HydrophobicContact CB-CG 4.47Å; A61-W665 HydrophobicContact CB-CZ3 3.97Å; E62-W665 HydrophobicContact CG-CH2 3.58Å; E62-W665 HydrophobicContact CG-CZ3 3.47Å; E62-W665 VanDerWaalsContact CG-CZ3 3.47Å; A76-W665 PolarHBondContact O-N 3.12Å; G624-W665 PolarHBondContact O-NE1 2.89Å; N625-W665 HydrophobicContact CB-CZ2 4.01Å; P626-W665 VanDerWaalsContact CD-CG 3.48Å; P626-W665 VanDerWaalsContact CD-NE1 3.31Å; P626-W665 HydrophobicContact CG-CB 3.96Å; P626-W665 HydrophobicContact CG-CD2 4.37Å; P626-W665 HydrophobicContact CG-CG 3.74Å; F663-W665 HydrophobicContact CE1-CB 4.4Å; F663-W665 HydrophobicContact CZ-CB 4.29Å; W665-K667 HydrophobicContact CH2-CB 3.63Å; W665-K667 HydrophobicContact CH2-CD 4.12Å; W665-K667 HydrophobicContact CH2-CG 3.98Å; W665-K667 HydrophobicContact CZ2-CB 4.13Å; W665-K667 HydrophobicContact CZ2-CG 4.43Å; W665-K667 HydrophobicContact CZ3-CB 3.92Å; W665-N673 HydrophobicContact CZ2-CB 4.18Å
666L94.9Very high95.6Very high88 Ų8839.4 Ų39.446%0.46120%0.204SC..EExtended strand (participates in β ladder)trans-111.6113.7-177.2-60.6174000109.5G668 N673 N674L666-G668 PolarHBondContact O-N 3.15Å; L666-G668 VanDerWaalsContact O-N 3.16Å; L666-N673 WeakPolarHBondContact O-CA 3.18Å; L666-N673 WeakPolarHBondContact O-CB 3.24Å; L666-N674 HydrophobicContact CB-CB 4.42Å; L666-N674 PolarHBondContact N-O 2.91Å; L666-N674 PolarHBondContact O-N 3.45Å
667K91.7Very high95.6Very high141 Ų14139.2 Ų39.261%0.61320%0.203SC*.EExtended strand (participates in β ladder)trans-70.6106.5171.1-170.5175.8-173.7166.20109.5E62 W665E62-K667 WeakPolarHBondContact OE1-CE 3.33Å; E62-K667 IonicContact OE1-NZ 3.51Å; E62-K667 PolarHBondContact OE1-NZ 3.32Å; W665-K667 HydrophobicContact CH2-CB 3.63Å; W665-K667 HydrophobicContact CH2-CD 4.12Å; W665-K667 HydrophobicContact CH2-CG 3.98Å; W665-K667 HydrophobicContact CZ2-CB 4.13Å; W665-K667 HydrophobicContact CZ2-CG 4.43Å; W665-K667 HydrophobicContact CZ3-CB 3.92Å
668G87.9Confident95.6Very high34 Ų3441.4 Ų41.435%0.35121%0.213SC..  trans-87.1-177.417600000113.1L666 Q672L666-G668 PolarHBondContact O-N 3.15Å; L666-G668 VanDerWaalsContact O-N 3.16Å; G668-Q672 CarbonylContact C-O 3.59Å; G668-Q672 VanDerWaalsContact C-O 3.31Å; G668-Q672 WeakPolarHBondContact CA-O 3.4Å; G668-Q672 PolarHBondContact N-O 3.38Å
669S87.1Confident95.6Very high98 Ų9841.4 Ų41.469%0.68521%0.213SC*.G310 helixtrans-75.3158.817868.10000110.8R671 Q672S669-R671 PolarHBondContact O-N 3.08Å; S669-Q672 PolarHBondContact O-N 3.2Å
670N87.9Confident95.7Very high93 Ų9342.9 Ų42.950%0.49722%0.22SC..G310 helixtrans54.228.2176.3-16627.9000114.7R593 Q672R593-N670 VanDerWaalsContact CD-O 3.3Å; R593-N670 WeakPolarHBondContact CD-O 3.32Å; R593-N670 PolarHBondContact NH1-OD1 3Å; N670-Q672 PolarHBondContact O-N 2.98Å
671R90.1Very high95.7Very high94 Ų9441.4 Ų41.436%0.35521%0.213SC..G310 helixtrans64.616.2-178.9-50175.8-74.7159.7-23.8114.3V591 R593 S669V591-R671 VanDerWaalsContact O-CD 3.27Å; V591-R671 WeakPolarHBondContact O-CD 3.34Å; V591-R671 PolarHBondContact O-NH1 3.49Å; R593-R671 HydrophobicContact CB-CB 4.41Å; R593-R671 HydrophobicContact CG-CB 4.26Å; R593-R671 PolarHBondContact N-O 3Å; R593-R671 VanDerWaalsContact NE-NH2 3.19Å; S669-R671 PolarHBondContact O-N 3.08Å
672Q94.4Very high95.5Very high51 Ų5142.5 Ų42.524%0.23822%0.22CC..BIsolated β-bridgetrans-85.8115.9167.3-65.4173.5-5.500107.4R593 K594 G668 S669 N670R593-Q672 HydrophobicContact CB-CG 3.91Å; R593-Q672 WeakPolarHBondContact O-CA 3.23Å; K594-Q672 PolarHBondContact O-NE2 3.31Å; G668-Q672 CarbonylContact C-O 3.59Å; G668-Q672 VanDerWaalsContact C-O 3.31Å; G668-Q672 WeakPolarHBondContact CA-O 3.4Å; G668-Q672 PolarHBondContact N-O 3.38Å; S669-Q672 PolarHBondContact O-N 3.2Å; N670-Q672 PolarHBondContact O-N 2.98Å
673N96.3Very high95.3Very high7 Ų745.7 Ų45.74%0.03725%0.248CC..EExtended strand (participates in β ladder)trans-110.9155.2179.1-38-72.4000109.6D592 A623 W665 L666D592-N673 PolarHBondContact OD1-ND2 3.07Å; A623-N673 PolarHBondContact N-O 3.48Å; A623-N673 CarbonylContact O-C 3.06Å; A623-N673 WeakPolarHBondContact O-CB 3.49Å; A623-N673 VanDerWaalsContact O-O 3.07Å; W665-N673 HydrophobicContact CZ2-CB 4.18Å; L666-N673 WeakPolarHBondContact O-CA 3.18Å; L666-N673 WeakPolarHBondContact O-CB 3.24Å
674N97.4Very high95Very high49 Ų4950.3 Ų50.326%0.26228%0.281SS..EExtended strand (participates in β ladder)trans-120.7150178.9-61.22.3000109.6L604 T620 F621 L666L604-N674 WeakPolarHBondContact CD1-OD1 3.25Å; T620-N674 HydrophobicContact CG2-CB 3.9Å; F621-N674 VanDerWaalsContact O-CA 3.29Å; F621-N674 WeakPolarHBondContact O-CA 3.2Å; L666-N674 HydrophobicContact CB-CB 4.42Å; L666-N674 PolarHBondContact N-O 2.91Å; L666-N674 PolarHBondContact O-N 3.45Å
675A98.2Very high94.9Very high0 Ų048.2 Ų48.20%027%0.271CS..EExtended strand (participates in β ladder)trans-114.9116.2167.400000108.4T620 F621 A623 F663 H664 H694T620-A675 CarbonylContact C-O 3.52Å; T620-A675 WeakPolarHBondContact CA-O 3.34Å; F621-A675 PolarHBondContact N-O 2.92Å; F621-A675 PolarHBondContact O-N 3.2Å; A623-A675 HydrophobicContact CB-CB 3.55Å; F663-A675 HydrophobicContact CE2-CB 3.73Å; H664-A675 CarbonylContact O-C 3.57Å; H664-A675 VanDerWaalsContact O-CA 3.3Å; H664-A675 WeakPolarHBondContact O-CA 3.33Å; A675-H694 WeakPolarHBondContact CB-NE2 3.31Å
676T98.6Very high94.7Very high17 Ų1751.4 Ų51.410%0.10429%0.293CS..EExtended strand (participates in β ladder)trans-103125.6172.3-59.20000108.3V619 T620 H664V619-T676 CarbonylContact O-C 3.47Å; V619-T676 WeakPolarHBondContact O-CA 3.08Å; T620-T676 PolarHBondContact OG1-OG1 2.73Å; H664-T676 WeakPolarHBondContact CB-O 3.5Å; H664-T676 PolarHBondContact N-O 2.77Å; H664-T676 PolarHBondContact O-N 3.34Å
677V98.7Very high94.8Very high0 Ų050.8 Ų50.80%030%0.3CS..EExtended strand (participates in β ladder)trans-109.5123176.7-178.30000108.2S618 V619 F621 V638 R662 F663 I692S618-V677 WeakPolarHBondContact CA-O 3.1Å; V619-V677 HydrophobicContact CG1-CB 4.04Å; V619-V677 PolarHBondContact N-O 3.22Å; V619-V677 PolarHBondContact O-N 3.14Å; F621-V677 HydrophobicContact CD2-CG2 4.39Å; F621-V677 HydrophobicContact CE2-CG2 4.04Å; V638-V677 HydrophobicContact CB-CG1 4.31Å; V638-V677 HydrophobicContact CG1-CG1 3.42Å; V638-V677 VanDerWaalsContact CG1-CG1 3.42Å; V638-V677 HydrophobicContact CG1-CG2 4.44Å; V638-V677 HydrophobicContact CG2-CB 4.35Å; V638-V677 HydrophobicContact CG2-CG1 3.88Å; V638-V677 HydrophobicContact CG2-CG2 3.52Å; R662-V677 WeakPolarHBondContact O-CA 3.41Å; F663-V677 HydrophobicContact CD2-CG2 4.41Å; V677-I692 HydrophobicContact CB-CG2 3.99Å; V677-I692 HydrophobicContact CG1-CG2 3.65Å; V677-I692 HydrophobicContact CG2-CG2 4.46Å
678E98.7Very high95Very high48 Ų4845.2 Ų45.222%0.22428%0.282CS..EExtended strand (participates in β ladder)trans-105.1137.4170.8-56.6-175.4151.600110I616 V617 T661 R662 H664 F680I616-E678 HydrophobicContact CG2-CB 4.24Å; V617-E678 CarbonylContact O-C 3.13Å; V617-E678 VanDerWaalsContact O-CA 3.24Å; V617-E678 WeakPolarHBondContact O-CA 3.19Å; T661-E678 CarbonylContact C-O 3.56Å; T661-E678 VanDerWaalsContact CA-O 3.3Å; T661-E678 WeakPolarHBondContact CA-O 3.47Å; R662-E678 HydrophobicContact CB-CB 4.25Å; R662-E678 PolarHBondContact N-O 3.33Å; R662-E678 IonicContact NH1-OE2 2.73Å; R662-E678 PolarHBondContact O-N 3.08Å; H664-E678 IonicContact NE2-OE2 3.96Å; E678-F680 HydrophobicContact CB-CD2 4.43Å; E678-F680 HydrophobicContact CB-CE2 3.85Å; E678-F680 WeakPolarHBondContact OE2-CE2 3.41Å
679W98.8Very high95.5Very high0 Ų045.8 Ų45.80%028%0.281CS..EExtended strand (participates in β ladder)trans-122.4113.9167.4174.341.4000109.7I616 V617 V640 Y654 I681 A685 Y690 I692 F718 V720I616-W679 WeakPolarHBondContact CA-O 3.42Å; V617-W679 HydrophobicContact CB-CB 4.3Å; V617-W679 HydrophobicContact CB-CE3 4.43Å; V617-W679 HydrophobicContact CG2-CE3 3.86Å; V617-W679 HydrophobicContact CG2-CZ3 4.47Å; V617-W679 PolarHBondContact N-O 2.98Å; V617-W679 PolarHBondContact O-N 3.01Å; V640-W679 HydrophobicContact CG1-CD2 3.77Å; V640-W679 HydrophobicContact CG1-CE3 3.62Å; V640-W679 HydrophobicContact CG1-CG 4.42Å; V640-W679 HydrophobicContact CG1-CH2 4.07Å; V640-W679 HydrophobicContact CG1-CZ2 4.21Å; V640-W679 HydrophobicContact CG1-CZ3 3.76Å; V640-W679 HydrophobicContact CG2-CB 4.07Å; V640-W679 HydrophobicContact CG2-CD2 4.1Å; V640-W679 HydrophobicContact CG2-CG 3.85Å; Y654-W679 AromaticContact CD2-CE2 3.83Å; Y654-W679 AromaticContact CD2-CZ2 4Å; Y654-W679 HydrophobicContact CD2-CZ2 4Å; Y654-W679 AromaticContact CD2-NE1 3.48Å; Y654-W679 AromaticContact CE2-CE2 3.74Å; Y654-W679 AromaticContact CE2-CZ2 3.56Å; Y654-W679 HydrophobicContact CE2-CZ2 3.56Å; Y654-W679 AromaticContact CE2-NE1 3.49Å; W679-I681 HydrophobicContact CD2-CG1 3.93Å; W679-I681 HydrophobicContact CE3-CG1 3.86Å; W679-I681 HydrophobicContact CH2-CG1 4.07Å; W679-I681 HydrophobicContact CH2-CG2 4.31Å; W679-I681 HydrophobicContact CZ2-CB 4.43Å; W679-I681 HydrophobicContact CZ2-CG1 4.13Å; W679-I681 HydrophobicContact CZ2-CG2 4.17Å; W679-I681 HydrophobicContact CZ3-CD1 4.42Å; W679-I681 HydrophobicContact CZ3-CG1 3.96Å; W679-I681 PolarHBondContact O-N 3.31Å; W679-A685 HydrophobicContact CZ2-CB 4.4Å; W679-Y690 AromaticContact CH2-CD1 3.53Å; W679-Y690 HydrophobicContact CH2-CD1 3.53Å; W679-Y690 HydrophobicContact CH2-CD2 4.19Å; W679-Y690 AromaticContact CH2-CE1 3.52Å; W679-Y690 HydrophobicContact CH2-CE1 3.52Å; W679-Y690 HydrophobicContact CH2-CE2 4.2Å; W679-Y690 AromaticContact CH2-CG 3.86Å; W679-Y690 HydrophobicContact CH2-CG 3.86Å; W679-Y690 AromaticContact CH2-CZ 3.87Å; W679-Y690 HydrophobicContact CZ2-CE1 4.26Å; W679-Y690 AromaticContact CZ3-CD1 3.75Å; W679-Y690 HydrophobicContact CZ3-CD1 3.75Å; W679-Y690 HydrophobicContact CZ3-CD2 4.32Å; W679-Y690 HydrophobicContact CZ3-CE1 4.23Å; W679-Y690 AromaticContact CZ3-CG 3.78Å; W679-Y690 HydrophobicContact CZ3-CG 3.78Å; W679-I692 HydrophobicContact CB-CD1 4.05Å; W679-F718 HydrophobicContact CE3-CE2 4.03Å; W679-F718 AromaticContact CE3-CZ 3.81Å; W679-F718 HydrophobicContact CE3-CZ 3.81Å; W679-F718 AromaticContact CZ3-CE2 3.66Å; W679-F718 HydrophobicContact CZ3-CE2 3.66Å; W679-F718 AromaticContact CZ3-CZ 3.73Å; W679-F718 HydrophobicContact CZ3-CZ 3.73Å; W679-V720 HydrophobicContact CH2-CG2 4.12Å; W679-V720 HydrophobicContact CZ3-CG2 3.96Å
680F98.4Very high96Very high55 Ų5541.1 Ų41.124%0.24125%0.249CC..EExtended strand (participates in β ladder)trans-82.897.4174.9-69.6-104.2000108I616 E660 R662 E678 P682I616-F680 HydrophobicContact CD1-CD1 3.85Å; I616-F680 HydrophobicContact CD1-CE1 3.31Å; I616-F680 HydrophobicContact CD1-CZ 3.88Å; I616-F680 HydrophobicContact CG1-CD1 3.68Å; I616-F680 HydrophobicContact CG1-CE1 3.67Å; I616-F680 HydrophobicContact CG1-CG 4.31Å; I616-F680 HydrophobicContact CG1-CZ 4.27Å; I616-F680 HydrophobicContact CG2-CD2 4.47Å; I616-F680 HydrophobicContact CG2-CE1 4.37Å; I616-F680 HydrophobicContact CG2-CE2 4.2Å; I616-F680 HydrophobicContact CG2-CZ 4.13Å; E660-F680 WeakPolarHBondContact O-CD2 3.48Å; E660-F680 PolarHBondContact O-N 3.43Å; R662-F680 HydrophobicContact CG-CE2 4.05Å; R662-F680 VanDerWaalsContact CZ-CE2 3.5Å; E678-F680 HydrophobicContact CB-CD2 4.43Å; E678-F680 HydrophobicContact CB-CE2 3.85Å; E678-F680 WeakPolarHBondContact OE2-CE2 3.41Å; F680-P682 WeakPolarHBondContact O-CD 3.35Å; F680-P682 VanDerWaalsContact O-N 3.11Å
681I98.3Very high96.6Very high4 Ų439.3 Ų39.32%0.02124%0.235CC..  trans-64.4114.6-172.9-57.7167.9000108.9Y611 Q613 G614 D615 V617 W679 A685 V720Y611-I681 HydrophobicContact CG-CD1 4.19Å; Q613-I681 HydrophobicContact CG-CG2 4.44Å; G614-I681 VanDerWaalsContact CA-O 3.28Å; G614-I681 WeakPolarHBondContact CA-O 3.11Å; G614-I681 PolarHBondContact N-O 3.3Å; D615-I681 HydrophobicContact CB-CD1 4.44Å; D615-I681 PolarHBondContact O-N 3.19Å; V617-I681 HydrophobicContact CG2-CD1 3.61Å; V617-I681 HydrophobicContact CG2-CG1 3.93Å; W679-I681 HydrophobicContact CD2-CG1 3.93Å; W679-I681 HydrophobicContact CE3-CG1 3.86Å; W679-I681 HydrophobicContact CH2-CG1 4.07Å; W679-I681 HydrophobicContact CH2-CG2 4.31Å; W679-I681 HydrophobicContact CZ2-CB 4.43Å; W679-I681 HydrophobicContact CZ2-CG1 4.13Å; W679-I681 HydrophobicContact CZ2-CG2 4.17Å; W679-I681 HydrophobicContact CZ3-CD1 4.42Å; W679-I681 HydrophobicContact CZ3-CG1 3.96Å; W679-I681 PolarHBondContact O-N 3.31Å; I681-A685 HydrophobicContact CG2-CB 3.66Å; I681-V720 HydrophobicContact CD1-CG1 4.17Å; I681-V720 HydrophobicContact CD1-CG2 3.82Å; I681-V720 HydrophobicContact CG2-CG1 3.71Å
682P95.8Very high97Very high25 Ų2534.8 Ų34.816%0.16222%0.218CC..  trans-68.7155.1178.626.9-31.7000110.8Y654 E660 F680 S684 A685Y654-P682 WeakPolarHBondContact OH-CG 3.33Å; E660-P682 HydrophobicContact CG-CB 4.49Å; E660-P682 HydrophobicContact CG-CG 4.21Å; F680-P682 WeakPolarHBondContact O-CD 3.35Å; F680-P682 VanDerWaalsContact O-N 3.11Å; P682-S684 PolarHBondContact O-N 2.71Å; P682-S684 VanDerWaalsContact O-N 3.14Å; P682-A685 HydrophobicContact CG-CB 3.99Å; P682-A685 VanDerWaalsContact O-CB 3.3Å; P682-A685 WeakPolarHBondContact O-CB 3.38Å; P682-A685 PolarHBondContact O-N 3.4Å
683S93.9Very high97.2Very high103 Ų10334.4 Ų34.472%0.7221%0.214SC*.THydrogen-bonded Turntrans-61.7-21.3176530000113.4
684S92.8Very high97.3Very high99 Ų9934.1 Ų34.169%0.69221%0.213SC*.THydrogen-bonded Turntrans-88.1-4.7176.253.20000114.4P682P682-S684 PolarHBondContact O-N 2.71Å; P682-S684 VanDerWaalsContact O-N 3.14Å
685A95.1Very high97.3Very high1 Ų134.1 Ų34.11%0.00821%0.211CC..PPolyproline II helixtrans-59.9131.5-178.600000110.8Q613 W679 I681 P682Q613-A685 PolarHBondContact NE2-O 3.18Å; W679-A685 HydrophobicContact CZ2-CB 4.4Å; I681-A685 HydrophobicContact CG2-CB 3.66Å; P682-A685 HydrophobicContact CG-CB 3.99Å; P682-A685 VanDerWaalsContact O-CB 3.3Å; P682-A685 WeakPolarHBondContact O-CB 3.38Å; P682-A685 PolarHBondContact O-N 3.4Å
686P94.3Very high97.3Very high73 Ų7334.4 Ų34.447%0.47421%0.213SC..PPolyproline II helixtrans-54.8147.4173.9-25.934.3000112.3I642 Y690I642-P686 HydrophobicContact CD1-CB 4.11Å; P686-Y690 WeakPolarHBondContact O-CE2 3.3Å; P686-Y690 PolarHBondContact O-OH 3.28Å
687A95.9Very high97.3Very high74 Ų7435.7 Ų35.761%0.61222%0.218SC*.SBendtrans-72.9135.5166.800000108.8V720A687-V720 CarbonylContact C-O 3.34Å; A687-V720 WeakPolarHBondContact CA-O 3.27Å
688G96.6Very high97.2Very high24 Ų2437.3 Ų37.325%0.24722%0.224CC..EExtended strand (participates in β ladder)trans172.1-176.5-175.300000114Y690 S719 V720G688-Y690 WeakPolarHBondContact O-CD2 3.49Å; G688-S719 WeakPolarHBondContact O-CA 3.48Å; G688-V720 PolarHBondContact N-O 2.95Å; G688-V720 PolarHBondContact O-N 2.88Å
689S98.3Very high97.2Very high47 Ų4737.3 Ų37.333%0.32922%0.223SC..EExtended strand (participates in β ladder)trans-94.8130.1172.8-68.10000109.7I642 Y643 F718I642-S689 WeakPolarHBondContact CA-O 3.36Å; Y643-S689 PolarHBondContact N-O 3.15Å; S689-F718 CarbonylContact C-O 3.59Å; S689-F718 WeakPolarHBondContact CA-O 3.47Å
690Y98.7Very high97Very high0 Ų039.9 Ų39.90%024%0.236CC..EExtended strand (participates in β ladder)trans-125.1157.3-175-71.2-91.5000111.2V640 E641 I642 V653 W679 P686 G688 V717 F718 V720V640-Y690 HydrophobicContact CG1-CD1 3.99Å; E641-Y690 CarbonylContact O-C 3.6Å; E641-Y690 WeakPolarHBondContact O-CA 3.44Å; E641-Y690 WeakPolarHBondContact O-CD1 3.27Å; I642-Y690 HydrophobicContact CB-CD1 3.96Å; I642-Y690 HydrophobicContact CB-CE1 3.61Å; I642-Y690 HydrophobicContact CD1-CE1 4.04Å; I642-Y690 HydrophobicContact CD1-CE2 4.2Å; I642-Y690 WeakPolarHBondContact CD1-OH 3.45Å; I642-Y690 HydrophobicContact CG1-CD1 4.21Å; I642-Y690 HydrophobicContact CG1-CE1 3.76Å; I642-Y690 HydrophobicContact CG1-CE2 4.13Å; V653-Y690 HydrophobicContact CG2-CD1 4.46Å; V653-Y690 HydrophobicContact CG2-CE1 4Å; W679-Y690 AromaticContact CH2-CD1 3.53Å; W679-Y690 HydrophobicContact CH2-CD1 3.53Å; W679-Y690 HydrophobicContact CH2-CD2 4.19Å; W679-Y690 AromaticContact CH2-CE1 3.52Å; W679-Y690 HydrophobicContact CH2-CE1 3.52Å; W679-Y690 HydrophobicContact CH2-CE2 4.2Å; W679-Y690 AromaticContact CH2-CG 3.86Å; W679-Y690 HydrophobicContact CH2-CG 3.86Å; W679-Y690 AromaticContact CH2-CZ 3.87Å; W679-Y690 HydrophobicContact CZ2-CE1 4.26Å; W679-Y690 AromaticContact CZ3-CD1 3.75Å; W679-Y690 HydrophobicContact CZ3-CD1 3.75Å; W679-Y690 HydrophobicContact CZ3-CD2 4.32Å; W679-Y690 HydrophobicContact CZ3-CE1 4.23Å; W679-Y690 AromaticContact CZ3-CG 3.78Å; W679-Y690 HydrophobicContact CZ3-CG 3.78Å; P686-Y690 WeakPolarHBondContact O-CE2 3.3Å; P686-Y690 PolarHBondContact O-OH 3.28Å; G688-Y690 WeakPolarHBondContact O-CD2 3.49Å; Y690-V717 WeakPolarHBondContact O-CA 3.34Å; Y690-F718 VanDerWaalsContact CB-CZ 3.49Å; Y690-F718 HydrophobicContact CG-CE2 4.4Å; Y690-F718 PolarHBondContact N-O 3.07Å; Y690-F718 WeakPolarHBondContact O-CD1 3.28Å; Y690-F718 PolarHBondContact O-N 2.89Å; Y690-V720 HydrophobicContact CD2-CB 3.77Å; Y690-V720 HydrophobicContact CD2-CG2 3.52Å; Y690-V720 HydrophobicContact CE2-CB 3.7Å; Y690-V720 HydrophobicContact CE2-CG1 4.48Å; Y690-V720 HydrophobicContact CE2-CG2 3.9Å; Y690-V720 HydrophobicContact CG-CG2 4.26Å
691R98.7Very high96.7Very high54 Ų5442.2 Ų42.220%0.20425%0.25CC..EExtended strand (participates in β ladder)trans-141.8156.216371.3-176.7-178.8178.1-1110.3E641 W650E641-R691 HydrophobicContact CB-CG 4.13Å; E641-R691 PolarHBondContact N-O 2.91Å; E641-R691 PolarHBondContact O-N 2.65Å; E641-R691 IonicContact OE2-CZ 3.43Å; E641-R691 IonicContact OE2-NE 3.88Å; E641-R691 PolarHBondContact OE2-NE 3Å; E641-R691 IonicContact OE2-NH2 2.6Å; E641-R691 PolarHBondContact OE2-NH2 3.3Å; W650-R691 HydrophobicContact CD2-CG 4.17Å; W650-R691 HydrophobicContact CE3-CG 3.77Å; W650-R691 HydrophobicContact CH2-CB 3.97Å; W650-R691 HydrophobicContact CH2-CG 3.88Å; W650-R691 HydrophobicContact CZ2-CG 4.28Å; W650-R691 HydrophobicContact CZ3-CB 4Å; W650-R691 HydrophobicContact CZ3-CG 3.62Å
692I98.9Very high96.2Very high0 Ų047.7 Ų47.70%027%0.273CS..EExtended strand (participates in β ladder)trans-109.9130.2172.9-63.5179.9000108.3V617 V619 T639 V640 V677 W679 S715 F718V617-I692 HydrophobicContact CB-CD1 4.14Å; V617-I692 HydrophobicContact CG1-CD1 3.64Å; V619-I692 HydrophobicContact CG1-CB 3.89Å; V619-I692 HydrophobicContact CG1-CD1 4.02Å; V619-I692 HydrophobicContact CG1-CG2 3.67Å; T639-I692 WeakPolarHBondContact O-CA 3.31Å; V640-I692 HydrophobicContact CG2-CG1 4.28Å; V677-I692 HydrophobicContact CB-CG2 3.99Å; V677-I692 HydrophobicContact CG1-CG2 3.65Å; V677-I692 HydrophobicContact CG2-CG2 4.46Å; W679-I692 HydrophobicContact CB-CD1 4.05Å; I692-S715 PolarHBondContact N-OG 3.03Å; I692-S715 PolarHBondContact O-N 2.74Å; I692-F718 HydrophobicContact CG1-CE1 4.16Å; I692-F718 HydrophobicContact CG1-CZ 4.3Å
693R98.7Very high95.9Very high43 Ų4349.8 Ų49.816%0.16230%0.3CS..EExtended strand (participates in β ladder)trans-114.6144.7172.4-58.1178.273.7-157.71111.2V638 T639 E641 F695 E712 G713V638-R693 WeakPolarHBondContact CA-O 3.26Å; T639-R693 PolarHBondContact N-O 3.06Å; T639-R693 PolarHBondContact O-N 3.16Å; E641-R693 VanDerWaalsContact CD-CD 3.5Å; E641-R693 WeakPolarHBondContact OE1-CD 3.46Å; E641-R693 IonicContact OE1-NH1 3.37Å; E641-R693 PolarHBondContact OE1-NH1 3.27Å; E641-R693 WeakPolarHBondContact OE2-CD 3.39Å; R693-F695 HydrophobicContact CB-CE2 4.16Å; R693-F695 HydrophobicContact CB-CZ 3.89Å; R693-E712 IonicContact CZ-OE2 2.78Å; R693-E712 IonicContact NH2-OE1 3.69Å; R693-E712 PolarHBondContact NH2-OE1 3.47Å; R693-E712 IonicContact NH2-OE2 3.79Å; R693-E712 PolarHBondContact NH2-OE2 2.91Å; R693-G713 CarbonylContact C-O 3.4Å; R693-G713 VanDerWaalsContact CA-O 3.22Å; R693-G713 WeakPolarHBondContact CA-O 3.39Å
694H98.6Very high95.5Very high1 Ų153.1 Ų53.11%0.00531%0.309CS..EExtended strand (participates in β ladder)trans-119.6136.2175.717447.6000110F621 F637 F663 A675 Y711 E712 G713F621-H694 HydrophobicContact CD1-CB 4.35Å; F621-H694 HydrophobicContact CD2-CB 3.55Å; F621-H694 HydrophobicContact CE1-CB 4.35Å; F621-H694 HydrophobicContact CE2-CB 3.55Å; F621-H694 HydrophobicContact CG-CB 3.97Å; F621-H694 HydrophobicContact CZ-CB 3.97Å; F637-H694 WeakPolarHBondContact O-CA 3.49Å; F637-H694 PolarHBondContact O-ND1 2.86Å; F663-H694 AromaticContact CE2-CE1 3.49Å; F663-H694 VanDerWaalsContact CE2-CE1 3.49Å; F663-H694 WeakPolarHBondContact CE2-CE1 3.36Å; F663-H694 AromaticContact CE2-ND1 3.87Å; A675-H694 WeakPolarHBondContact CB-NE2 3.31Å; H694-Y711 AromaticContact CD2-CE2 3.81Å; H694-Y711 AromaticContact NE2-CE2 3.82Å; H694-Y711 AromaticContact NE2-CZ 3.79Å; H694-Y711 PolarHBondContact NE2-OH 3.39Å; H694-E712 CarbonylContact O-C 3.42Å; H694-E712 VanDerWaalsContact O-CA 3.23Å; H694-E712 WeakPolarHBondContact O-CA 3.46Å; H694-G713 PolarHBondContact N-O 2.93Å; H694-G713 PolarHBondContact O-N 2.72Å
695F98.5Very high95.4Very high49 Ų4952 Ų5222%0.21530%0.301CS..EExtended strand (participates in β ladder)trans-120.5142.5177.3-49.1-83.7000109.3T636 F637 T639 R693 E712T636-F695 HydrophobicContact CG2-CD2 4.24Å; T636-F695 HydrophobicContact CG2-CE2 4.28Å; T636-F695 WeakPolarHBondContact O-CD2 3.24Å; F637-F695 VanDerWaalsContact CD1-O 3.26Å; F637-F695 WeakPolarHBondContact CD1-O 3.22Å; F637-F695 PolarHBondContact O-N 2.03Å; T639-F695 HydrophobicContact CG2-CE2 3.88Å; T639-F695 WeakPolarHBondContact OG1-CE2 3.32Å; R693-F695 HydrophobicContact CB-CE2 4.16Å; R693-F695 HydrophobicContact CB-CZ 3.89Å; F695-E712 HydrophobicContact CD1-CB 3.93Å; F695-E712 HydrophobicContact CE1-CB 4.27Å
696G97.9Very high95.3Very high5 Ų555.9 Ų55.95%0.05233%0.326CS..EExtended strand (participates in β ladder)trans-167.7-177.1176.300000113.6P710 Y711G696-P710 CarbonylContact O-C 3.55Å; G696-P710 WeakPolarHBondContact O-CA 3.08Å; G696-Y711 VanDerWaalsContact C-CD1 3.43Å; G696-Y711 PolarHBondContact N-O 3.17Å; G696-Y711 VanDerWaalsContact O-CD1 3.24Å; G696-Y711 WeakPolarHBondContact O-CD1 3.21Å; G696-Y711 PolarHBondContact O-N 2.78Å
697H98.1Very high95.4Very high44 Ų4454.6 Ų54.620%0.20432%0.317CS..EExtended strand (participates in β ladder)trans-128.7145.1174.7-63.376.9000109.7G624 H628 S629 I708 T709G624-H697 WeakPolarHBondContact CA-O 3.4Å; H628-H697 HydrophobicContact CB-CB 4.15Å; S629-H697 WeakPolarHBondContact CA-ND1 3.41Å; S629-H697 VanDerWaalsContact CB-ND1 3.34Å; S629-H697 WeakPolarHBondContact CB-ND1 3.38Å; S629-H697 PolarHBondContact OG-ND1 3.05Å; H697-I708 HydrophobicContact CB-CG2 3.8Å; H697-T709 WeakPolarHBondContact CA-O 3.26Å
698Y97.5Very high95.4Very high35 Ų3555.3 Ų55.314%0.13731%0.309CS..EExtended strand (participates in β ladder)trans-125.3152.6173.374.7-88.7000110.3D592 F600 E700 I708 T709 Y711D592-Y698 WeakPolarHBondContact OD2-CA 3.36Å; F600-Y698 HydrophobicContact CB-CD1 3.96Å; F600-Y698 HydrophobicContact CB-CE1 4.38Å; F600-Y698 HydrophobicContact CD1-CD1 4.48Å; F600-Y698 HydrophobicContact CD1-CG 4.21Å; F600-Y698 AromaticContact CD2-CD1 3.41Å; F600-Y698 HydrophobicContact CD2-CD1 3.41Å; F600-Y698 VanDerWaalsContact CD2-CD1 3.41Å; F600-Y698 AromaticContact CD2-CD2 3.51Å; F600-Y698 HydrophobicContact CD2-CD2 3.51Å; F600-Y698 AromaticContact CD2-CE1 3.68Å; F600-Y698 HydrophobicContact CD2-CE1 3.68Å; F600-Y698 AromaticContact CD2-CE2 3.76Å; F600-Y698 HydrophobicContact CD2-CE2 3.76Å; F600-Y698 AromaticContact CD2-CG 3.32Å; F600-Y698 HydrophobicContact CD2-CG 3.32Å; F600-Y698 AromaticContact CD2-CZ 3.86Å; F600-Y698 HydrophobicContact CE1-CG 4.27Å; F600-Y698 AromaticContact CE2-CD1 3.99Å; F600-Y698 HydrophobicContact CE2-CD1 3.99Å; F600-Y698 AromaticContact CE2-CD2 3.17Å; F600-Y698 HydrophobicContact CE2-CD2 3.17Å; F600-Y698 HydrophobicContact CE2-CE1 4.36Å; F600-Y698 AromaticContact CE2-CE2 3.6Å; F600-Y698 HydrophobicContact CE2-CE2 3.6Å; F600-Y698 AromaticContact CE2-CG 3.4Å; F600-Y698 HydrophobicContact CE2-CG 3.4Å; F600-Y698 AromaticContact CG-CD1 3.71Å; F600-Y698 HydrophobicContact CG-CD1 3.71Å; F600-Y698 HydrophobicContact CG-CD2 4.38Å; F600-Y698 HydrophobicContact CG-CE1 4.28Å; F600-Y698 AromaticContact CG-CG 3.77Å; F600-Y698 HydrophobicContact CG-CG 3.77Å; F600-Y698 AromaticContact CZ-CD2 3.82Å; F600-Y698 HydrophobicContact CZ-CD2 3.82Å; F600-Y698 AromaticContact CZ-CG 3.89Å; F600-Y698 HydrophobicContact CZ-CG 3.89Å; Y698-E700 HydrophobicContact CD2-CB 4.3Å; Y698-E700 HydrophobicContact CE2-CB 3.96Å; Y698-E700 HydrophobicContact CE2-CG 3.85Å; Y698-E700 WeakPolarHBondContact CE2-OE2 3.37Å; Y698-I708 WeakPolarHBondContact O-CA 3.35Å; Y698-T709 VanDerWaalsContact CD1-O 3.31Å; Y698-T709 WeakPolarHBondContact CD1-O 2.95Å; Y698-T709 HydrophobicContact CE1-CG2 3.95Å; Y698-T709 PolarHBondContact N-O 3.23Å; Y698-T709 PolarHBondContact O-N 3.43Å; Y698-Y711 AromaticContact CD1-CD1 3.85Å; Y698-Y711 HydrophobicContact CD1-CD1 3.85Å
699K96.9Very high95.5Very high48 Ų4855.8 Ų55.821%0.20931%0.307CS..EExtended strand (participates in β ladder)trans-107.2125.7177.2-179.5-179.7177.6177.80110.5A589 V591 D592 H628 P706 V707 I708A589-K699 PolarHBondContact O-NZ 3.42Å; V591-K699 CarbonylContact C-O 3.58Å; V591-K699 WeakPolarHBondContact CA-O 3.23Å; V591-K699 WeakPolarHBondContact CG1-O 3.49Å; V591-K699 HydrophobicContact CG2-CD 4.41Å; V591-K699 HydrophobicContact CG2-CG 4.21Å; D592-K699 PolarHBondContact N-O 3.3Å; D592-K699 PolarHBondContact OD2-N 3.04Å; H628-K699 WeakPolarHBondContact CE1-CB 3.41Å; H628-K699 VanDerWaalsContact CE1-CD 3.42Å; H628-K699 WeakPolarHBondContact CE1-CD 3.34Å; H628-K699 WeakPolarHBondContact NE2-CB 3.34Å; K699-P706 HydrophobicContact CG-CB 4.43Å; K699-V707 WeakPolarHBondContact CA-O 2.99Å; K699-I708 HydrophobicContact CB-CG1 4.47Å
700E94.6Very high95.4Very high54 Ų5457.7 Ų57.725%0.25232%0.319SS..EExtended strand (participates in β ladder)trans-125.4166.8172.565.5-179-178.100111.9Y698 K702 P706 V707Y698-E700 HydrophobicContact CD2-CB 4.3Å; Y698-E700 HydrophobicContact CE2-CB 3.96Å; Y698-E700 HydrophobicContact CE2-CG 3.85Å; Y698-E700 WeakPolarHBondContact CE2-OE2 3.37Å; E700-K702 HydrophobicContact CG-CG 4.45Å; E700-K702 WeakPolarHBondContact OE1-CE 3.23Å; E700-K702 IonicContact OE1-NZ 3.07Å; E700-P706 CarbonylContact O-C 3.48Å; E700-P706 WeakPolarHBondContact O-CA 2.9Å; E700-V707 PolarHBondContact N-O 3.21Å; E700-V707 PolarHBondContact O-N 2.94Å
701L92.4Very high95.4Very high103 Ų10359 Ų5954%0.53932%0.324SS..EExtended strand (participates in β ladder)trans-100.6115.4170.8-71.7168.8000109V591 P706V591-L701 HydrophobicContact CG2-CD1 4.22Å; V591-L701 HydrophobicContact CG2-CD2 4.38Å; V591-L701 HydrophobicContact CG2-CG 3.83Å; L701-P706 HydrophobicContact CD2-CB 4.39Å
702K88.8Confident95.4Very high119 Ų11962 Ų6252%0.51734%0.34SS..EExtended strand (participates in β ladder)trans-9799.2165.9-65.9-167.7-174.4175.70107.7E700 L704 S705 V707E700-K702 HydrophobicContact CG-CG 4.45Å; E700-K702 WeakPolarHBondContact OE1-CE 3.23Å; E700-K702 IonicContact OE1-NZ 3.07Å; K702-L704 PolarHBondContact O-N 2.97Å; K702-S705 PolarHBondContact N-O 2.99Å; K702-S705 PolarHBondContact O-N 3.06Å; K702-V707 HydrophobicContact CB-CG2 3.92Å; K702-V707 HydrophobicContact CD-CB 4.33Å; K702-V707 HydrophobicContact CD-CG1 4.44Å; K702-V707 HydrophobicContact CD-CG2 3.99Å; K702-V707 HydrophobicContact CG-CB 4.27Å; K702-V707 HydrophobicContact CG-CG2 3.9Å
703G87.9Confident95.4Very high70 Ų7062.3 Ų62.372%0.72234%0.343SS*.THydrogen-bonded Turntrans67.1-120.8-167.700000111.1
704L86.6Confident95.3Very high173 Ų17362.4 Ų62.491%0.90635%0.351SS*.THydrogen-bonded Turntrans-97.1-4.5176.8-65.8173.9000113.7K702K702-L704 PolarHBondContact O-N 2.97Å
705S90.7Very high95.4Very high76 Ų7662.7 Ų62.753%0.53135%0.353SS..EExtended strand (participates in β ladder)trans-100.8131.5-175.1-62.10000111.4K702K702-S705 PolarHBondContact N-O 2.99Å; K702-S705 PolarHBondContact O-N 3.06Å
706P92.7Very high95.4Very high82 Ų8265.2 Ų65.253%0.53237%0.369SS..EExtended strand (participates in β ladder)trans-71132.6170.529.4-32.2000110.3K699 E700 L701K699-P706 HydrophobicContact CG-CB 4.43Å; E700-P706 CarbonylContact O-C 3.48Å; E700-P706 WeakPolarHBondContact O-CA 2.9Å; L701-P706 HydrophobicContact CD2-CB 4.39Å
707V95.9Very high95.4Very high45 Ų4568.8 Ų68.827%0.27339%0.389SS..EExtended strand (participates in β ladder)trans-123.1132.9175.3-179.30000108.4K699 E700 K702K699-V707 WeakPolarHBondContact CA-O 2.99Å; E700-V707 PolarHBondContact N-O 3.21Å; E700-V707 PolarHBondContact O-N 2.94Å; K702-V707 HydrophobicContact CB-CG2 3.92Å; K702-V707 HydrophobicContact CD-CB 4.33Å; K702-V707 HydrophobicContact CD-CG1 4.44Å; K702-V707 HydrophobicContact CD-CG2 3.99Å; K702-V707 HydrophobicContact CG-CB 4.27Å; K702-V707 HydrophobicContact CG-CG2 3.9Å
708I96.9Very high95.4Very high89 Ų8966.9 Ų66.946%0.45638%0.38SS..EExtended strand (participates in β ladder)trans-101.5127.4173.9-62.8176.5000107.3H628 H697 Y698 K699H628-I708 HydrophobicContact CB-CD1 4.33Å; H628-I708 HydrophobicContact CB-CG2 4.16Å; H628-I708 WeakPolarHBondContact O-CG2 3.38Å; H697-I708 HydrophobicContact CB-CG2 3.8Å; Y698-I708 WeakPolarHBondContact O-CA 3.35Å; K699-I708 HydrophobicContact CB-CG1 4.47Å
709T97.5Very high95.4Very high34 Ų3466.3 Ų66.321%0.20938%0.382CS..EExtended strand (participates in β ladder)trans-127.1131.3-177-51.50000109.5H697 Y698H697-T709 WeakPolarHBondContact CA-O 3.26Å; Y698-T709 VanDerWaalsContact CD1-O 3.31Å; Y698-T709 WeakPolarHBondContact CD1-O 2.95Å; Y698-T709 HydrophobicContact CE1-CG2 3.95Å; Y698-T709 PolarHBondContact N-O 3.23Å; Y698-T709 PolarHBondContact O-N 3.43Å
710P97.8Very high95.4Very high88 Ų8864.3 Ų64.357%0.57137%0.374SS*.EExtended strand (participates in β ladder)trans-70.1153.1172.829.7-34.3000111.2G696G696-P710 CarbonylContact O-C 3.55Å; G696-P710 WeakPolarHBondContact O-CA 3.08Å
711Y98.1Very high95.4Very high27 Ų2762.4 Ų62.411%0.10637%0.368CS..EExtended strand (participates in β ladder)trans-145.5161.8170.769.7-84.5000110.1F600 G601 A623 G624 H694 G696 Y698F600-Y711 VanDerWaalsContact C-CD2 3.49Å; F600-Y711 HydrophobicContact CB-CD1 3.87Å; F600-Y711 HydrophobicContact CB-CD2 3.87Å; F600-Y711 HydrophobicContact CB-CE1 4.28Å; F600-Y711 HydrophobicContact CB-CE2 4.28Å; F600-Y711 HydrophobicContact CB-CG 3.64Å; G601-Y711 VanDerWaalsContact N-CD2 3.27Å; A623-Y711 WeakPolarHBondContact CA-OH 3.4Å; A623-Y711 VanDerWaalsContact CB-OH 3.29Å; A623-Y711 WeakPolarHBondContact CB-OH 3.45Å; G624-Y711 PolarHBondContact N-OH 3.24Å; H694-Y711 AromaticContact CD2-CE2 3.81Å; H694-Y711 AromaticContact NE2-CE2 3.82Å; H694-Y711 AromaticContact NE2-CZ 3.79Å; H694-Y711 PolarHBondContact NE2-OH 3.39Å; G696-Y711 VanDerWaalsContact C-CD1 3.43Å; G696-Y711 PolarHBondContact N-O 3.17Å; G696-Y711 VanDerWaalsContact O-CD1 3.24Å; G696-Y711 WeakPolarHBondContact O-CD1 3.21Å; G696-Y711 PolarHBondContact O-N 2.78Å; Y698-Y711 AromaticContact CD1-CD1 3.85Å; Y698-Y711 HydrophobicContact CD1-CD1 3.85Å
712E98.2Very high95.1Very high116 Ų11662.4 Ų62.454%0.54238%0.377SS..EExtended strand (participates in β ladder)trans-136.8152.4171.357.5172.5-130.300110.5R693 H694 F695R693-E712 IonicContact CZ-OE2 2.78Å; R693-E712 IonicContact NH2-OE1 3.69Å; R693-E712 PolarHBondContact NH2-OE1 3.47Å; R693-E712 IonicContact NH2-OE2 3.79Å; R693-E712 PolarHBondContact NH2-OE2 2.91Å; H694-E712 CarbonylContact O-C 3.42Å; H694-E712 VanDerWaalsContact O-CA 3.23Å; H694-E712 WeakPolarHBondContact O-CA 3.46Å; F695-E712 HydrophobicContact CD1-CB 3.93Å; F695-E712 HydrophobicContact CE1-CB 4.27Å
713G98.3Very high94.6Very high7 Ų759 Ų597%0.07237%0.368CS..EExtended strand (participates in β ladder)trans-133151.5174.400000110.6G601 R693 H694G601-G713 WeakPolarHBondContact O-CA 3.26Å; R693-G713 CarbonylContact C-O 3.4Å; R693-G713 VanDerWaalsContact CA-O 3.22Å; R693-G713 WeakPolarHBondContact CA-O 3.39Å; H694-G713 PolarHBondContact N-O 2.93Å; H694-G713 PolarHBondContact O-N 2.72Å
714S98.6Very high93.9Very high46 Ų4661 Ų6132%0.32236%0.355SS..EExtended strand (participates in β ladder)trans-132136.2175.6-1760000109.9V603V603-S714 WeakPolarHBondContact CG2-O 3.43Å
715S98.7Very high92.4Very high6 Ų662.1 Ų62.14%0.04235%0.348CS..PPolyproline II helixtrans-65.4168.1164.975.30000110.8I692I692-S715 PolarHBondContact N-OG 3.03Å; I692-S715 PolarHBondContact O-N 2.74Å
716D98.6Very high90.4Very high103 Ų10365 Ų6555%0.55135%0.353SS*.PPolyproline II helixtrans-64.5160.9161.3-71.5-22.2000109.5Q606 V607Q606-D716 HydrophobicContact CG-CB 4.19Å; Q606-D716 WeakPolarHBondContact CG-OD2 3.44Å; Q606-D716 PolarHBondContact NE2-OD1 3.03Å; Q606-D716 PolarHBondContact NE2-OD2 3.11Å; Q606-D716 VanDerWaalsContact NE2-OD2 3.1Å; V607-D716 HydrophobicContact CG2-CB 4.35Å
717V98.5Very high88.1Confident80 Ų8066.2 Ų66.249%0.48536%0.364SS..PPolyproline II helixtrans-74.1133.4173.3178.90000109.2W650 Y690W650-V717 HydrophobicContact CH2-CB 4.46Å; W650-V717 HydrophobicContact CH2-CG1 4.02Å; W650-V717 HydrophobicContact CH2-CG2 3.73Å; W650-V717 HydrophobicContact CZ2-CG2 3.67Å; Y690-V717 WeakPolarHBondContact O-CA 3.34Å
718F98.4Very high85.4Confident3 Ų372.1 Ų72.11%0.01339%0.388CS..EExtended strand (participates in β ladder)trans-128.7159.117562-85.1000110.7V607 L608 P609 Y611 V617 W679 S689 Y690 I692 V720V607-F718 HydrophobicContact CB-CD1 4.14Å; V607-F718 HydrophobicContact CG1-CD1 4.24Å; V607-F718 HydrophobicContact CG1-CE1 4.32Å; V607-F718 HydrophobicContact CG2-CB 4.13Å; V607-F718 HydrophobicContact CG2-CD1 3.75Å; V607-F718 HydrophobicContact CG2-CG 4.26Å; L608-F718 WeakPolarHBondContact O-CB 2.95Å; P609-F718 WeakPolarHBondContact O-CA 3.22Å; Y611-F718 HydrophobicContact CD2-CB 4.35Å; Y611-F718 AromaticContact CD2-CD2 3.58Å; Y611-F718 HydrophobicContact CD2-CD2 3.58Å; Y611-F718 HydrophobicContact CD2-CE2 4.16Å; Y611-F718 HydrophobicContact CD2-CG 4.18Å; Y611-F718 HydrophobicContact CE2-CB 4.39Å; Y611-F718 HydrophobicContact CE2-CD2 4.02Å; Y611-F718 HydrophobicContact CE2-CG 4.24Å; V617-F718 HydrophobicContact CB-CZ 4.38Å; V617-F718 HydrophobicContact CG1-CE1 4.08Å; V617-F718 HydrophobicContact CG1-CE2 4.18Å; V617-F718 HydrophobicContact CG1-CZ 3.81Å; V617-F718 HydrophobicContact CG2-CD2 4.4Å; V617-F718 HydrophobicContact CG2-CE2 3.63Å; V617-F718 HydrophobicContact CG2-CZ 3.93Å; W679-F718 HydrophobicContact CE3-CE2 4.03Å; W679-F718 AromaticContact CE3-CZ 3.81Å; W679-F718 HydrophobicContact CE3-CZ 3.81Å; W679-F718 AromaticContact CZ3-CE2 3.66Å; W679-F718 HydrophobicContact CZ3-CE2 3.66Å; W679-F718 AromaticContact CZ3-CZ 3.73Å; W679-F718 HydrophobicContact CZ3-CZ 3.73Å; S689-F718 CarbonylContact C-O 3.59Å; S689-F718 WeakPolarHBondContact CA-O 3.47Å; Y690-F718 VanDerWaalsContact CB-CZ 3.49Å; Y690-F718 HydrophobicContact CG-CE2 4.4Å; Y690-F718 PolarHBondContact N-O 3.07Å; Y690-F718 WeakPolarHBondContact O-CD1 3.28Å; Y690-F718 PolarHBondContact O-N 2.89Å; I692-F718 HydrophobicContact CG1-CE1 4.16Å; I692-F718 HydrophobicContact CG1-CZ 4.3Å; F718-V720 HydrophobicContact CD2-CG2 3.98Å; F718-V720 HydrophobicContact CE2-CG2 3.73Å
719S97.6Very high82.8Confident24 Ų2475 Ų7517%0.16840%0.404CS..EExtended strand (participates in β ladder)trans-104.5142.5178.9600000111.6P609 V610 Y611 G688P609-S719 PolarHBondContact O-N 3.31Å; P609-S719 PolarHBondContact O-OG 3.22Å; V610-S719 CarbonylContact C-O 3.34Å; V610-S719 WeakPolarHBondContact CA-O 2.96Å; Y611-S719 PolarHBondContact N-O 3.03Å; G688-S719 WeakPolarHBondContact O-CA 3.48Å
720V97.6Very high79.7Confident6 Ų681.8 Ų81.84%0.03643%0.433CS..EExtended strand (participates in β ladder)trans-119.3135.1173.5177.40000108.8Y611 Q613 W679 I681 A687 G688 Y690 F718Y611-V720 WeakPolarHBondContact O-CA 3.24Å; Q613-V720 HydrophobicContact CG-CG1 4.34Å; W679-V720 HydrophobicContact CH2-CG2 4.12Å; W679-V720 HydrophobicContact CZ3-CG2 3.96Å; I681-V720 HydrophobicContact CD1-CG1 4.17Å; I681-V720 HydrophobicContact CD1-CG2 3.82Å; I681-V720 HydrophobicContact CG2-CG1 3.71Å; A687-V720 CarbonylContact C-O 3.34Å; A687-V720 WeakPolarHBondContact CA-O 3.27Å; G688-V720 PolarHBondContact N-O 2.95Å; G688-V720 PolarHBondContact O-N 2.88Å; Y690-V720 HydrophobicContact CD2-CB 3.77Å; Y690-V720 HydrophobicContact CD2-CG2 3.52Å; Y690-V720 HydrophobicContact CE2-CB 3.7Å; Y690-V720 HydrophobicContact CE2-CG1 4.48Å; Y690-V720 HydrophobicContact CE2-CG2 3.9Å; Y690-V720 HydrophobicContact CG-CG2 4.26Å; F718-V720 HydrophobicContact CD2-CG2 3.98Å; F718-V720 HydrophobicContact CE2-CG2 3.73Å
721G93.6Very high76.7Confident14 Ų1482.9 Ų82.914%0.14444%0.44CS..EExtended strand (participates in β ladder)trans-154.8-177.1175.600000113.5Y611 R612 Q613 S723Y611-G721 PolarHBondContact O-N 3.16Å; R612-G721 CarbonylContact C-O 3.47Å; R612-G721 VanDerWaalsContact CA-O 3.28Å; R612-G721 WeakPolarHBondContact CA-O 3.47Å; Q613-G721 PolarHBondContact N-O 2.78Å; G721-S723 VanDerWaalsContact C-N 3.32Å
722S86.1Confident73.7Confident102 Ų10287.5 Ų87.571%0.71347%0.471SS*.SBendtrans-78.3-13.8177.857.30000113.7
723S77.4Confident70.8Confident49 Ų4989.9 Ų89.934%0.34348%0.482SS..SBendtrans-148.3162.1177.186.70000110.8G721 Y725G721-S723 VanDerWaalsContact C-N 3.32Å; S723-Y725 PolarHBondContact O-N 3.13Å; S723-Y725 PolarHBondContact OG-N 3.06Å; S723-Y725 PolarHBondContact OG-O 2.03Å
724Y73.7Confident67.6Low111 Ų11195.9 Ų95.944%0.43551%0.512SS..SBendtrans-72.8-6.5173.7-69.1-42.4000113.1V610 R612 D615V610-Y724 HydrophobicContact CG1-CD1 4.2Å; R612-Y724 HydrophobicContact CB-CE1 4.24Å; R612-Y724 HydrophobicContact CG-CD1 3.66Å; R612-Y724 HydrophobicContact CG-CE1 3.49Å; R612-Y724 VanDerWaalsContact CG-CE1 3.49Å; R612-Y724 HydrophobicContact CG-CE2 4.41Å; R612-Y724 HydrophobicContact CG-CG 4.16Å; R612-Y724 VanDerWaalsContact NE-CZ 3.29Å; D615-Y724 PolarHBondContact OD1-OH 2.81Å; D615-Y724 WeakPolarHBondContact OD2-CE1 3.48Å; D615-Y724 PolarHBondContact OD2-OH 2.92Å
725Y56.4Low64.6Low197 Ų197102.4 Ų102.477%0.77354%0.537SS*.SBendtrans-87.3123.3177.9-67.2-76.5000109.6S723 S727S723-Y725 PolarHBondContact O-N 3.13Å; S723-Y725 PolarHBondContact OG-N 3.06Å; S723-Y725 PolarHBondContact OG-O 2.03Å; Y725-S727 PolarHBondContact O-N 2.91Å
726H48.9Very low61.6Low137 Ų137109.1 Ų109.163%0.63457%0.573SS**  trans-58.8118.5158-87.5-26.1000107.7H728H726-H728 VanDerWaalsContact C-N 3.27Å; H726-H728 PolarHBondContact O-N 3.47Å
727S42.8Very low58.6Low107 Ų107113.3 Ų113.375%0.74861%0.611SS**  trans-60.4100.4158.153.20000106.6Y725 D729Y725-S727 PolarHBondContact O-N 2.91Å; S727-D729 PolarHBondContact O-N 2.95Å
728H40.5Very low56.6Low169 Ų169115 Ų11578%0.78262%0.617SS**  trans-65.374.9163-83.917.8000108.2H726H726-H728 VanDerWaalsContact C-N 3.27Å; H726-H728 PolarHBondContact O-N 3.47Å
729D40.9Very low54.4Low150 Ų150120.9 Ų120.980%0.80265%0.649SS**  trans-127.765.9161.1-87.7-30.8000107.4S727S727-D729 PolarHBondContact O-N 2.95Å
730Q32.8Very low52Low175 Ų175126.3 Ų126.382%0.81868%0.675SS**SBendtrans-114.4131.5147-77-134.3-28.400107.5V732Q730-V732 PolarHBondContact O-N 3.18Å; Q730-V732 VanDerWaalsContact O-N 3.15Å
731P35.5Very low49.3Very low111 Ų111133.4 Ų133.472%0.72171%0.713SS**  trans-66119.4-179.926.8-30.4000108.5H733P731-H733 VanDerWaalsContact C-N 3.35Å; P731-H733 PolarHBondContact O-N 3.18Å
732V34.3Very low46.5Very low124 Ų124140.8 Ų140.875%0.75275%0.748SS**  trans-60.8100.5165.9179.70000106.9Q730 N734Q730-V732 PolarHBondContact O-N 3.18Å; Q730-V732 VanDerWaalsContact O-N 3.15Å; V732-N734 PolarHBondContact O-N 3.34Å
733H36.8Very low43.9Very low167 Ų167143.4 Ų143.477%0.77375%0.751SS**  trans-67.392.8160.6-88-63.3000107.5P731 H735P731-H733 VanDerWaalsContact C-N 3.35Å; P731-H733 PolarHBondContact O-N 3.18Å; H733-H735 PolarHBondContact O-N 2.83Å
734N31.7Very low41.5Very low132 Ų132150.1 Ų150.171%0.70678%0.78SS**  trans-58.9103162.2-91.3-16.3000108.4V732 N736V732-N734 PolarHBondContact O-N 3.34Å; N734-N736 PolarHBondContact O-N 3.36Å
735H35.2Very low39Very low183 Ų183153.2 Ų153.285%0.84781%0.806SS**  trans-78.296.7154.7-90-60.1000108.2H733H733-H735 PolarHBondContact O-N 2.83Å
736N35.9Very low37.5Very low148 Ų148149.5 Ų149.579%0.79181%0.809SS**  trans-96.6117.7156-100.1-10.8000107.9N734N734-N736 PolarHBondContact O-N 3.36Å
737S35.1Very low36.5Very low191 Ų191150.6 Ų150.6100%1.33683%0.825SS**  trans129.10158740000113

Retrieved 737 of 737 residues in 480.4 ms (Link to these results)