A0A087XM21_POEFO Loading...

Solute carrier family 7 member 5

AlphaFold DB , UniProt , Accession A0A087XM21, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 527 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	R	35.6	Very low	31.5	Very low	301 Å²	301	168.1 Å²	168.1	100%	1.136	81%	0.81	S	S	*	*				0	115.6	0	-108.3	175.3	173	176.2	-3.3	108.2
2	K	30.6	Very low	31	Very low	194 Å²	194	168.3 Å²	168.3	84%	0.843	80%	0.804	S	S	*	*			trans	47.5	109.2	156.2	-68.1	-178.9	176.8	179	0	118.5
3	R	28.8	Very low	30.6	Very low	237 Å²	237	168.2 Å²	168.2	89%	0.894	80%	0.798	S	S	*	*				63.5	122	89.4	-75.7	-175.2	173.6	-178.7	-1.6	111.2
4	K	28.7	Very low	30.3	Very low	204 Å²	204	171 Å²	171	89%	0.887	80%	0.797	S	S	*	*				-164.5	129.8	63	-83	-179.7	172.9	177.7	0	111.7
5	Q	37	Very low	29.9	Very low	178 Å²	178	168.2 Å²	168.2	83%	0.832	79%	0.79	S	S	*	*			trans	-71	171	142.6	-113.6	-179.6	5.9	0	0	108.5
6	P	47.7	Very low	29.9	Very low	97 Å²	97	163.4 Å²	163.4	63%	0.63	78%	0.781	S	S	*	*				-162.8	170.2	51.4	40.8	-16.6	0	0	0	121.1
7	Q	29.4	Very low	29.6	Very low	156 Å²	156	163.2 Å²	163.2	73%	0.729	79%	0.785	S	S	*	*			trans	70.8	149.3	138.4	-76.7	170.8	-4.5	0	0	120.2
8	M	29.3	Very low	30.1	Very low	146 Å²	146	160.2 Å²	160.2	72%	0.719	78%	0.784	S	S	*	*			cis	-165.4	141.9	13.6	-128.9	172.3	-168.7	0	0	110.9
9	S	26.8	Very low	30.1	Very low	111 Å²	111	158.1 Å²	158.1	78%	0.776	79%	0.787	S	S	*	*				85	126.4	117.2	70.1	0	0	0	0	116.2
10	S	25.1	Very low	30.3	Very low	105 Å²	105	152.9 Å²	152.9	73%	0.734	78%	0.775	S	S	*	*				-167	126	60.1	171.2	0	0	0	0	108.9
11	V	27.2	Very low	30.6	Very low	120 Å²	120	148.4 Å²	148.4	73%	0.727	77%	0.767	S	S	*	*				50	121.7	83	-172.6	0	0	0	0	112.3
12	K	25.9	Very low	30.7	Very low	171 Å²	171	145 Å²	145	74%	0.743	75%	0.754	S	S	*	*				-179.6	141.6	60.1	-142.6	167.8	-177.5	176.9	0	113.3
13	K	25.7	Very low	30.9	Very low	166 Å²	166	143 Å²	143	72%	0.722	75%	0.747	S	S	*	*			trans	51.4	121.1	134.5	-75.2	-177	178.7	-180	0	125.2
14	R	25.9	Very low	31.5	Very low	208 Å²	208	138.6 Å²	138.6	79%	0.785	74%	0.737	S	S	*	*				82.3	128.3	104.7	-150.9	-176.4	-167.9	175.1	8.3	121.8
15	N	24.7	Very low	32.1	Very low	129 Å²	129	134.4 Å²	134.4	69%	0.69	73%	0.725	S	S	*	*			trans	103.2	120.2	139.2	-98.2	19	0	0	0	122.5
16	S	30.1	Very low	32.2	Very low	92 Å²	92	134.5 Å²	134.5	64%	0.643	72%	0.717	S	S	*	*			trans	50.4	120.4	134.1	63.1	0	0	0	0	121.6
17	N	24.9	Very low	31.6	Very low	160 Å²	160	136.5 Å²	136.5	86%	0.856	72%	0.718	S	S	*	*				-165.8	143.5	112.7	-111.4	-4.5	0	0	0	114.2
18	S	38.2	Very low	32.2	Very low	109 Å²	109	133.5 Å²	133.5	76%	0.762	71%	0.71	S	S	*	*			trans	-84.7	128.9	175.8	53.8	0	0	0	0	112.1
19	S	31.1	Very low	32.6	Very low	120 Å²	120	130.6 Å²	130.6	84%	0.839	70%	0.701	S	S	*	*			trans	-175.4	73.3	158.9	53.9	0	0	0	0	110.9
20	G	33.6	Very low	33.1	Very low	54 Å²	54	131.4 Å²	131.4	56%	0.557	69%	0.693	S	S	*	*	S	Bend	trans	-134.5	-31	175.9	0	0	0	0	0	114.9	R22	G20-R22 PolarHBondContact O-N 3.11Å
21	G	35.9	Very low	33.6	Very low	58 Å²	58	136.9 Å²	136.9	60%	0.598	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.6	3.8	-172.3	0	0	0	0	0	116.9
22	R	37.5	Very low	34.1	Very low	230 Å²	230	138.8 Å²	138.8	87%	0.868	70%	0.7	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.2	-15.5	-178.3	-100.1	-177.3	179.1	175.7	-0	114.5	G20	G20-R22 PolarHBondContact O-N 3.11Å
23	E	36.2	Very low	34.6	Very low	151 Å²	151	137.7 Å²	137.7	71%	0.706	70%	0.702	S	S	*	*	H	α-helix	trans	-87.5	-32.9	178.2	-88.7	173.3	153.1	0	0	112.4	R26 Q27	E23-R26 PolarHBondContact O-N 3.45Å; E23-Q27 PolarHBondContact O-N 3.18Å
24	E	41.4	Very low	34.9	Very low	146 Å²	146	134.6 Å²	134.6	68%	0.682	70%	0.701	S	S	*	*	H	α-helix	trans	-66.5	-41.1	175.5	-74.2	-174.8	150	0	0	112.3	R26 Q27 V28	E24-R26 VanDerWaalsContact C-N 3.27Å; E24-R26 PolarHBondContact O-N 2.99Å; E24-Q27 PolarHBondContact O-N 2.9Å; E24-V28 WeakPolarHBondContact O-CG2 3.37Å; E24-V28 PolarHBondContact O-N 3.17Å
25	D	41.3	Very low	35.3	Very low	116 Å²	116	129.6 Å²	129.6	62%	0.62	70%	0.704	S	S	*	*	H	α-helix	trans	-66.5	-28.8	176.8	-83.3	-15.7	0	0	0	112.7	T29	D25-T29 PolarHBondContact O-N 2.89Å; D25-T29 PolarHBondContact O-OG1 2.96Å
26	R	38.9	Very low	35.6	Very low	179 Å²	179	126.9 Å²	126.9	68%	0.675	71%	0.706	S	S	*	*	H	α-helix	trans	-77.6	-37.5	-179.7	-148.4	175.7	-176.3	-178.6	-0.3	111.8	E23 E24 V28 T29 E30	E23-R26 PolarHBondContact O-N 3.45Å; E24-R26 VanDerWaalsContact C-N 3.27Å; E24-R26 PolarHBondContact O-N 2.99Å; R26-V28 VanDerWaalsContact C-N 3.35Å; R26-T29 PolarHBondContact O-N 3.41Å; R26-E30 PolarHBondContact O-N 2.94Å
27	Q	35.2	Very low	35.5	Very low	139 Å²	139	128.1 Å²	128.1	65%	0.65	72%	0.715	S	S	*	*	H	α-helix	trans	-68.1	-31.6	174.9	-80	-174.7	-5.8	0	0	113.2	E23 E24 R31	E23-Q27 PolarHBondContact O-N 3.18Å; E24-Q27 PolarHBondContact O-N 2.9Å; Q27-R31 PolarHBondContact O-N 3.11Å
28	V	41.2	Very low	35.6	Very low	93 Å²	93	126.1 Å²	126.1	56%	0.564	71%	0.713	S	S	*	*	H	α-helix	trans	-71.7	-35.4	173.8	176.2	0	0	0	0	111.2	E24 R26	E24-V28 WeakPolarHBondContact O-CG2 3.37Å; E24-V28 PolarHBondContact O-N 3.17Å; R26-V28 VanDerWaalsContact C-N 3.35Å
29	T	38.3	Very low	36	Very low	86 Å²	86	126.5 Å²	126.5	53%	0.528	71%	0.714	S	S	.	*	H	α-helix	trans	-72.4	-36.3	179.1	-47.8	0	0	0	0	112.3	D25 R26 M32	D25-T29 PolarHBondContact O-N 2.89Å; D25-T29 PolarHBondContact O-OG1 2.96Å; R26-T29 PolarHBondContact O-N 3.41Å; T29-M32 PolarHBondContact O-N 2.98Å
30	E	36.8	Very low	35.9	Very low	128 Å²	128	125.9 Å²	125.9	60%	0.598	72%	0.716	S	S	*	*	H	α-helix	trans	-72.3	-28.6	178.7	-81.8	-179.9	170.5	0	0	113.6	R26 M32 L33	R26-E30 PolarHBondContact O-N 2.94Å; E30-M32 VanDerWaalsContact C-N 3.28Å; E30-M32 PolarHBondContact O-N 2.95Å; E30-L33 PolarHBondContact O-N 3.03Å
31	R	36.3	Very low	35.5	Very low	219 Å²	219	126.7 Å²	126.7	83%	0.826	72%	0.724	S	S	*	*	H	α-helix	trans	-74	-14.7	174.1	-80.6	-172.4	178.1	178.1	1.4	114.3	Q27	Q27-R31 PolarHBondContact O-N 3.11Å
32	M	37.2	Very low	35.3	Very low	161 Å²	161	130.9 Å²	130.9	79%	0.793	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.4	-9.9	175.2	-73.3	-162	169.3	0	0	113.9	T29 E30	T29-M32 PolarHBondContact O-N 2.98Å; E30-M32 VanDerWaalsContact C-N 3.28Å; E30-M32 PolarHBondContact O-N 2.95Å
33	L	35.8	Very low	35.4	Very low	148 Å²	148	125.9 Å²	125.9	78%	0.775	74%	0.736	S	S	*	*	S	Bend	trans	-105.9	-1.5	-172.6	-74	166.2	0	0	0	115.1	E30	E30-L33 PolarHBondContact O-N 3.03Å
34	S	32.5	Very low	35	Very low	101 Å²	101	122.5 Å²	122.5	71%	0.706	74%	0.741	S	S	*	*	S	Bend	trans	-116.1	7.2	-172.5	67	0	0	0	0	117.1
35	A	33.2	Very low	34.4	Very low	102 Å²	102	120.6 Å²	120.6	84%	0.843	74%	0.744	S	S	*	*			trans	-104.9	79.5	177.7	0	0	0	0	0	111.7
36	G	31.4	Very low	33.8	Very low	72 Å²	72	122.9 Å²	122.9	74%	0.742	76%	0.756	S	S	*	*			trans	-176.9	82.3	172	0	0	0	0	0	115
37	S	28.2	Very low	33.4	Very low	118 Å²	118	118.6 Å²	118.6	83%	0.825	76%	0.759	S	S	*	*			trans	-168.9	109.4	153.8	56	0	0	0	0	113.3
38	S	27.4	Very low	33	Very low	118 Å²	118	124 Å²	124	83%	0.825	77%	0.773	S	S	*	*			trans	-13.7	-176.6	158.1	-56.8	0	0	0	0	122.8
39	P	47.4	Very low	32.3	Very low	118 Å²	118	124.8 Å²	124.8	77%	0.766	78%	0.783	S	S	*	*			cis	-139.5	177.1	-44.2	36.6	-17.6	0	0	0	116.5
40	A	28	Very low	32.5	Very low	107 Å²	107	126.3 Å²	126.3	88%	0.884	80%	0.795	S	S	*	*			trans	80	131	145.8	0	0	0	0	0	123.8
41	G	25.9	Very low	32.1	Very low	71 Å²	71	126.1 Å²	126.1	73%	0.732	81%	0.808	S	S	*	*			trans	150.4	84.6	150.8	0	0	0	0	0	119.9
42	T	30.5	Very low	31.9	Very low	145 Å²	145	121.2 Å²	121.2	89%	0.89	81%	0.807	S	S	*	*			trans	44.7	160.2	141.7	32.4	0	0	0	0	125
43	P	41.1	Very low	31.5	Very low	126 Å²	126	121.7 Å²	121.7	82%	0.818	81%	0.812	S	S	*	*			trans	-110.1	164.8	-141.1	42.4	-34.9	0	0	0	116.2
44	G	27.9	Very low	31.3	Very low	80 Å²	80	122 Å²	122	83%	0.825	81%	0.813	S	S	*	*			trans	-149.6	127.7	169.6	0	0	0	0	0	111.9
45	S	27.6	Very low	31.2	Very low	105 Å²	105	123.3 Å²	123.3	73%	0.734	82%	0.819	S	S	*	*			trans	-68.2	146.2	178.2	50	0	0	0	0	113.5
46	D	28.4	Very low	31.1	Very low	165 Å²	165	122.9 Å²	122.9	88%	0.882	82%	0.816	S	S	*	*				-171	143.5	123.4	-93.9	-20.3	0	0	0	113
47	A	30.2	Very low	31	Very low	89 Å²	89	127 Å²	127	74%	0.736	82%	0.821	S	S	*	*			trans	-86.3	145.6	-171	0	0	0	0	0	113.3
48	R	27.9	Very low	31	Very low	251 Å²	251	126 Å²	126	95%	0.947	82%	0.82	S	S	*	*				172.4	124.9	128.8	-93	166.9	-162.7	-166	6.4	111.1
49	S	26.8	Very low	31.2	Very low	110 Å²	110	124.4 Å²	124.4	77%	0.769	81%	0.814	S	S	*	*			trans	-103.9	-179.8	165.5	58.2	0	0	0	0	109.4
50	P	42.7	Very low	30.4	Very low	119 Å²	119	127.8 Å²	127.8	77%	0.773	82%	0.819	S	S	*	*			cis	-132.4	155.8	-10	33.6	-15.3	0	0	0	113.4
51	S	26.8	Very low	30.6	Very low	124 Å²	124	130.9 Å²	130.9	87%	0.867	82%	0.821	S	S	*	*			trans	-146.9	127	151.6	50.1	0	0	0	0	111.1
52	S	32.6	Very low	30.9	Very low	116 Å²	116	130.2 Å²	130.2	81%	0.811	81%	0.814	S	S	*	*			trans	-65.4	118.3	-176	49.5	0	0	0	0	112.7
53	L	30.2	Very low	31.4	Very low	171 Å²	171	130.9 Å²	130.9	90%	0.895	82%	0.817	S	S	*	*			trans	-142.3	127.1	153.1	-83.6	168.8	0	0	0	108.7
54	L	30.5	Very low	31.6	Very low	155 Å²	155	129 Å²	129	81%	0.812	81%	0.813	S	S	*	*			trans	-18.8	145.5	173.1	-59.8	157.8	0	0	0	116.9	A56	L54-A56 PolarHBondContact O-N 2.88Å; L54-A56 VanDerWaalsContact O-N 3.08Å
55	P	30.6	Very low	33	Very low	127 Å²	127	129.9 Å²	129.9	83%	0.825	80%	0.798	S	S	*	*			trans	-67.9	113	174	21.3	-17.5	0	0	0	109.5
56	A	30.1	Very low	34.9	Very low	94 Å²	94	133 Å²	133	78%	0.777	80%	0.798	S	S	*	*			trans	-60.2	137.3	163	0	0	0	0	0	108.7	L54 A58	L54-A56 PolarHBondContact O-N 2.88Å; L54-A56 VanDerWaalsContact O-N 3.08Å; A56-A58 PolarHBondContact O-N 2.89Å
57	D	30.1	Very low	37.2	Very low	159 Å²	159	132.7 Å²	132.7	85%	0.85	79%	0.785	S	S	*	*			trans	-36.3	117.7	178.1	-68.2	-55	0	0	0	112	A59	D57-A59 PolarHBondContact O-N 3.47Å
58	A	27.8	Very low	39.5	Very low	97 Å²	97	132 Å²	132	80%	0.802	77%	0.772	S	S	*	*			trans	-60.1	96.7	155.5	0	0	0	0	0	106.1	A56 E60	A56-A58 PolarHBondContact O-N 2.89Å; A58-E60 VanDerWaalsContact C-N 3.33Å; A58-E60 PolarHBondContact O-N 2.81Å
59	A	31.9	Very low	42	Very low	84 Å²	84	121 Å²	121	69%	0.694	73%	0.731	S	S	*	*			trans	-58.1	103.8	165.2	0	0	0	0	0	106.5	D57 D61	D57-A59 PolarHBondContact O-N 3.47Å; A59-D61 PolarHBondContact O-N 3.26Å; A59-D61 VanDerWaalsContact O-N 3.08Å
60	E	31.8	Very low	44.9	Very low	189 Å²	189	118.3 Å²	118.3	88%	0.883	71%	0.71	S	S	*	*			trans	-55.8	113.2	160.7	-73.9	-175.8	152.9	0	0	106.6	A58 G62	A58-E60 VanDerWaalsContact C-N 3.33Å; A58-E60 PolarHBondContact O-N 2.81Å; E60-G62 PolarHBondContact O-N 3.3Å
61	D	31.3	Very low	46.9	Very low	172 Å²	172	114.6 Å²	114.6	92%	0.92	68%	0.684	S	S	*	*			trans	-65.8	66.6	167.7	-88.5	-36.8	0	0	0	109.3	A59	A59-D61 PolarHBondContact O-N 3.26Å; A59-D61 VanDerWaalsContact O-N 3.08Å
62	G	33.4	Very low	49.6	Very low	56 Å²	56	115.2 Å²	115.2	58%	0.577	67%	0.674	S	S	*	*			trans	-87.1	122.9	168.3	0	0	0	0	0	109.1	E60 A64	E60-G62 PolarHBondContact O-N 3.3Å; G62-A64 VanDerWaalsContact C-N 3.3Å; G62-A64 PolarHBondContact O-N 2.91Å
63	V	39.2	Very low	51.8	Low	159 Å²	159	113.3 Å²	113.3	96%	0.964	66%	0.655	S	S	*	*			trans	-64.3	91.9	169.3	-179.6	0	0	0	0	108.5
64	A	47.2	Very low	54.2	Low	88 Å²	88	105.2 Å²	105.2	73%	0.727	61%	0.613	S	S	*	*	P	Polyproline II helix	trans	-91.2	140	178.9	0	0	0	0	0	111.5	G62 K66	G62-A64 VanDerWaalsContact C-N 3.3Å; G62-A64 PolarHBondContact O-N 2.91Å; A64-K66 PolarHBondContact O-N 3.33Å
65	L	55.8	Low	56.8	Low	97 Å²	97	98.5 Å²	98.5	51%	0.508	58%	0.578	S	S	.	*	P	Polyproline II helix	trans	-61.5	129.5	174.3	-77.5	164.6	0	0	0	110.6	R67 E286	L65-R67 PolarHBondContact O-N 2.83Å; L65-E286 HydrophobicContact CB-CG 4.15Å; L65-E286 HydrophobicContact CD1-CG 4.28Å
66	K	67.5	Low	59.1	Low	170 Å²	170	95.4 Å²	95.4	74%	0.739	56%	0.564	S	S	*	*	P	Polyproline II helix	trans	-74.1	126.6	-177.9	-167.4	176.5	-176.7	177.1	0	110.8	A64 T68	A64-K66 PolarHBondContact O-N 3.33Å; K66-T68 HydrophobicContact CB-CG2 4.32Å; K66-T68 HydrophobicContact CD-CG2 4.27Å; K66-T68 HydrophobicContact CG-CG2 4.04Å; K66-T68 PolarHBondContact O-N 3.37Å; K66-T68 VanDerWaalsContact O-N 3.15Å
67	R	76.9	Confident	61.4	Low	159 Å²	159	93.7 Å²	93.7	60%	0.6	54%	0.541	S	S	*	.			trans	-67.1	109.2	173.5	-68.6	-178.4	-179.7	173.7	2.2	110.8	L65 E285 E286 I288	L65-R67 PolarHBondContact O-N 2.83Å; R67-E285 WeakPolarHBondContact CG-O 3.38Å; R67-E286 CarbonylContact C-O 3.6Å; R67-E286 VanDerWaalsContact CA-O 3.32Å; R67-E286 WeakPolarHBondContact CA-O 3.47Å; R67-I288 HydrophobicContact CB-CG1 4.37Å
68	T	79.6	Confident	64	Low	76 Å²	76	86.2 Å²	86.2	47%	0.466	50%	0.501	S	S	.	.			trans	-134	-15.4	-175.4	54.8	0	0	0	0	113.6	K66 T70 E286	K66-T68 HydrophobicContact CB-CG2 4.32Å; K66-T68 HydrophobicContact CD-CG2 4.27Å; K66-T68 HydrophobicContact CG-CG2 4.04Å; K66-T68 PolarHBondContact O-N 3.37Å; K66-T68 VanDerWaalsContact O-N 3.15Å; T68-T70 PolarHBondContact O-N 2.97Å; T68-E286 PolarHBondContact N-O 3.17Å
69	I	78.5	Confident	66.7	Low	18 Å²	18	82.5 Å²	82.5	9%	0.092	47%	0.468	C	S	.	.	B	Isolated β-bridge	trans	-83.2	114.6	-175.9	-58	177.5	0	0	0	109.7	N73 I77 V283 E286 M287 I288	I69-N73 HydrophobicContact CG2-CB 3.9Å; I69-I77 HydrophobicContact CD1-CD1 4.3Å; I69-I77 HydrophobicContact CG2-CD1 4.04Å; I69-V283 HydrophobicContact CD1-CB 3.77Å; I69-V283 HydrophobicContact CD1-CG1 4.42Å; I69-V283 HydrophobicContact CD1-CG2 4.02Å; I69-E286 HydrophobicContact CD1-CB 3.75Å; I69-E286 HydrophobicContact CG1-CB 4.16Å; I69-E286 PolarHBondContact N-O 2.95Å; I69-M287 HydrophobicContact CB-CB 4.44Å; I69-I288 PolarHBondContact O-N 3.5Å
70	T	87.7	Confident	68.9	Low	54 Å²	54	79.7 Å²	79.7	33%	0.331	45%	0.448	S	S	.	.			trans	-82.3	170.5	175.5	67.9	0	0	0	0	111.9	T68 M72 N73 G74 I288	T68-T70 PolarHBondContact O-N 2.97Å; T70-M72 VanDerWaalsContact C-N 3.34Å; T70-M72 PolarHBondContact O-N 2.7Å; T70-N73 WeakPolarHBondContact O-CB 3.23Å; T70-N73 PolarHBondContact O-N 3.45Å; T70-N73 PolarHBondContact OG1-N 3.36Å; T70-N73 PolarHBondContact OG1-ND2 3.48Å; T70-N73 PolarHBondContact OG1-OD1 2.97Å; T70-G74 PolarHBondContact O-N 2.75Å; T70-I288 HydrophobicContact CG2-CD1 4.06Å
71	L	85.8	Confident	71	Confident	42 Å²	42	73.4 Å²	73.4	22%	0.22	42%	0.422	C	S	.	.	H	α-helix	trans	-55.4	-45.6	174	176	62.4	0	0	0	112.7	N73 G74 V75 N293 R296 A297	L71-N73 VanDerWaalsContact C-N 3.33Å; L71-N73 PolarHBondContact O-N 3.39Å; L71-G74 PolarHBondContact O-N 3.43Å; L71-G74 VanDerWaalsContact O-N 3.15Å; L71-V75 WeakPolarHBondContact O-CG2 3.39Å; L71-V75 PolarHBondContact O-N 3.48Å; L71-N293 HydrophobicContact CB-CB 4.34Å; L71-N293 HydrophobicContact CD1-CB 4.24Å; L71-N293 WeakPolarHBondContact CD1-O 3.25Å; L71-R296 HydrophobicContact CD1-CB 3.71Å; L71-R296 HydrophobicContact CD2-CB 4.43Å; L71-A297 HydrophobicContact CD1-CB 3.99Å
72	M	82.9	Confident	73.6	Confident	136 Å²	136	65.4 Å²	65.4	67%	0.67	38%	0.379	S	S	*	.	H	α-helix	trans	-65.7	-39	179.5	-71.3	-55	-59.3	0	0	111.6	T70 G74 V75 A76	T70-M72 VanDerWaalsContact C-N 3.34Å; T70-M72 PolarHBondContact O-N 2.7Å; M72-G74 VanDerWaalsContact C-N 3.31Å; M72-G74 PolarHBondContact O-N 3.32Å; M72-V75 PolarHBondContact O-N 3.48Å; M72-A76 WeakPolarHBondContact O-CB 3.23Å; M72-A76 PolarHBondContact O-N 2.79Å
73	N	78.5	Confident	76.1	Confident	77 Å²	77	62.8 Å²	62.8	41%	0.412	35%	0.352	S	S	.	.	H	α-helix	trans	-62.3	-42	172.7	-63.1	-3.2	0	0	0	110.2	I69 T70 L71 A76 I77	I69-N73 HydrophobicContact CG2-CB 3.9Å; T70-N73 WeakPolarHBondContact O-CB 3.23Å; T70-N73 PolarHBondContact O-N 3.45Å; T70-N73 PolarHBondContact OG1-N 3.36Å; T70-N73 PolarHBondContact OG1-ND2 3.48Å; T70-N73 PolarHBondContact OG1-OD1 2.97Å; L71-N73 VanDerWaalsContact C-N 3.33Å; L71-N73 PolarHBondContact O-N 3.39Å; N73-A76 PolarHBondContact O-N 2.82Å; N73-I77 WeakPolarHBondContact O-CB 3.09Å; N73-I77 WeakPolarHBondContact O-CD1 3.46Å; N73-I77 WeakPolarHBondContact O-CG1 3.4Å; N73-I77 PolarHBondContact O-N 3.33Å
74	G	80.5	Confident	77.9	Confident	0 Å²	0	55.5 Å²	55.5	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-60.9	-44.1	175.6	0	0	0	0	0	113.6	T70 L71 M72 I77 I78	T70-G74 PolarHBondContact O-N 2.75Å; L71-G74 PolarHBondContact O-N 3.43Å; L71-G74 VanDerWaalsContact O-N 3.15Å; M72-G74 VanDerWaalsContact C-N 3.31Å; M72-G74 PolarHBondContact O-N 3.32Å; G74-I77 PolarHBondContact O-N 3.42Å; G74-I78 PolarHBondContact O-N 3.32Å
75	V	84.9	Confident	79.2	Confident	14 Å²	14	51.5 Å²	51.5	9%	0.085	28%	0.276	C	S	.	.	H	α-helix	trans	-62.7	-47	174.4	173.6	0	0	0	0	110.7	L71 M72 I77 I78 V79 A297 I300	L71-V75 WeakPolarHBondContact O-CG2 3.39Å; L71-V75 PolarHBondContact O-N 3.48Å; M72-V75 PolarHBondContact O-N 3.48Å; V75-I77 VanDerWaalsContact C-N 3.31Å; V75-I77 PolarHBondContact O-N 3.01Å; V75-I78 PolarHBondContact O-N 3.22Å; V75-V79 HydrophobicContact CG1-CG2 4.14Å; V75-V79 WeakPolarHBondContact O-CB 3.41Å; V75-V79 WeakPolarHBondContact O-CG2 3.3Å; V75-V79 PolarHBondContact O-N 3.02Å; V75-A297 HydrophobicContact CG2-CB 4.17Å; V75-I300 HydrophobicContact CG1-CG2 4.19Å; V75-I300 HydrophobicContact CG2-CB 4.23Å; V75-I300 HydrophobicContact CG2-CG2 4.13Å
76	A	80.6	Confident	80.6	Confident	63 Å²	63	47.1 Å²	47.1	52%	0.521	25%	0.254	S	S	.	.	H	α-helix	trans	-62.2	-38.2	178.3	0	0	0	0	0	112	M72 N73 G80	M72-A76 WeakPolarHBondContact O-CB 3.23Å; M72-A76 PolarHBondContact O-N 2.79Å; N73-A76 PolarHBondContact O-N 2.82Å; A76-G80 VanDerWaalsContact O-CA 3.31Å; A76-G80 WeakPolarHBondContact O-CA 3.25Å; A76-G80 PolarHBondContact O-N 3.22Å
77	I	78.6	Confident	81.6	Confident	58 Å²	58	39 Å²	39	30%	0.297	22%	0.219	S	C	.	.	H	α-helix	trans	-63.4	-48.9	174.4	-71.8	163.5	0	0	0	110.3	I69 N73 G74 V75 T81 L280	I69-I77 HydrophobicContact CD1-CD1 4.3Å; I69-I77 HydrophobicContact CG2-CD1 4.04Å; N73-I77 WeakPolarHBondContact O-CB 3.09Å; N73-I77 WeakPolarHBondContact O-CD1 3.46Å; N73-I77 WeakPolarHBondContact O-CG1 3.4Å; N73-I77 PolarHBondContact O-N 3.33Å; G74-I77 PolarHBondContact O-N 3.42Å; V75-I77 VanDerWaalsContact C-N 3.31Å; V75-I77 PolarHBondContact O-N 3.01Å; I77-T81 WeakPolarHBondContact O-CB 3.39Å; I77-T81 PolarHBondContact O-N 3.09Å; I77-T81 PolarHBondContact O-OG1 3.32Å; I77-L280 HydrophobicContact CG2-CD1 4.37Å
78	I	83	Confident	82.1	Confident	2 Å²	2	31.5 Å²	31.5	1%	0.01	19%	0.191	C	C	.	.	H	α-helix	trans	-64.4	-54.1	-179.8	-67.7	175.5	0	0	0	110.8	G74 V75 G80 T81 I82 L280 A297 I298 S301	G74-I78 PolarHBondContact O-N 3.32Å; V75-I78 PolarHBondContact O-N 3.22Å; I78-G80 VanDerWaalsContact C-N 3.26Å; I78-G80 PolarHBondContact O-N 2.85Å; I78-T81 PolarHBondContact O-N 3.36Å; I78-I82 HydrophobicContact CG2-CD1 3.38Å; I78-I82 HydrophobicContact CG2-CG1 4.06Å; I78-I82 WeakPolarHBondContact O-CG1 3.32Å; I78-I82 PolarHBondContact O-N 2.92Å; I78-L280 HydrophobicContact CD1-CB 4.08Å; I78-L280 HydrophobicContact CD1-CD2 3.42Å; I78-L280 VanDerWaalsContact CD1-CD2 3.42Å; I78-L280 HydrophobicContact CD1-CG 4.28Å; I78-L280 HydrophobicContact CG1-CB 3.98Å; I78-L280 HydrophobicContact CG1-CD2 3.96Å; I78-L280 HydrophobicContact CG1-CG 4.37Å; I78-A297 HydrophobicContact CD1-CB 4.27Å; I78-I298 HydrophobicContact CD1-CG1 3.82Å; I78-S301 WeakPolarHBondContact CD1-OG 3.1Å; I78-S301 WeakPolarHBondContact CG2-OG 3.09Å
79	V	84.4	Confident	82.2	Confident	18 Å²	18	28.8 Å²	28.8	11%	0.109	17%	0.174	C	C	.	.	H	α-helix	trans	-59.2	-43.5	-179	175.2	0	0	0	0	110	V75 T81 I83 V305	V75-V79 HydrophobicContact CG1-CG2 4.14Å; V75-V79 WeakPolarHBondContact O-CB 3.41Å; V75-V79 WeakPolarHBondContact O-CG2 3.3Å; V75-V79 PolarHBondContact O-N 3.02Å; V79-T81 VanDerWaalsContact C-N 3.32Å; V79-T81 PolarHBondContact O-N 3.19Å; V79-I83 HydrophobicContact CG1-CD1 3.57Å; V79-I83 HydrophobicContact CG1-CG1 4.21Å; V79-I83 WeakPolarHBondContact O-CB 3.37Å; V79-I83 VanDerWaalsContact O-CG1 3.3Å; V79-I83 WeakPolarHBondContact O-CG1 3.29Å; V79-I83 PolarHBondContact O-N 3.43Å; V79-V305 HydrophobicContact CG2-CG2 4.27Å
80	G	78	Confident	82.7	Confident	26 Å²	26	28 Å²	28	27%	0.268	17%	0.169	S	C	.	.	H	α-helix	trans	-69.1	-22.9	177	0	0	0	0	0	114.3	A76 I78 K223	A76-G80 VanDerWaalsContact O-CA 3.31Å; A76-G80 WeakPolarHBondContact O-CA 3.25Å; A76-G80 PolarHBondContact O-N 3.22Å; I78-G80 VanDerWaalsContact C-N 3.26Å; I78-G80 PolarHBondContact O-N 2.85Å; G80-K223 PolarHBondContact O-NZ 3.4Å
81	T	77.4	Confident	82.9	Confident	56 Å²	56	25.4 Å²	25.4	34%	0.344	15%	0.154	S	C	.	.	H	α-helix	trans	-88.2	-42.9	177.3	-56.2	0	0	0	0	110.8	I77 I78 V79 Y279	I77-T81 WeakPolarHBondContact O-CB 3.39Å; I77-T81 PolarHBondContact O-N 3.09Å; I77-T81 PolarHBondContact O-OG1 3.32Å; I78-T81 PolarHBondContact O-N 3.36Å; V79-T81 VanDerWaalsContact C-N 3.32Å; V79-T81 PolarHBondContact O-N 3.19Å; T81-Y279 HydrophobicContact CG2-CD2 4.3Å; T81-Y279 HydrophobicContact CG2-CG 4.28Å
82	I	85.3	Confident	83.1	Confident	4 Å²	4	23.8 Å²	23.8	2%	0.021	15%	0.146	C	C	.	.	H	α-helix	trans	-73.1	-46.8	-177.5	-60.3	174.3	0	0	0	111.3	I78 G84 W277 L302 V305 Y309	I78-I82 HydrophobicContact CG2-CD1 3.38Å; I78-I82 HydrophobicContact CG2-CG1 4.06Å; I78-I82 WeakPolarHBondContact O-CG1 3.32Å; I78-I82 PolarHBondContact O-N 2.92Å; I82-G84 PolarHBondContact O-N 3.32Å; I82-W277 HydrophobicContact CD1-CB 3.79Å; I82-W277 HydrophobicContact CG1-CB 4.49Å; I82-L302 HydrophobicContact CD1-CD2 3.35Å; I82-V305 HydrophobicContact CB-CG1 4.41Å; I82-V305 HydrophobicContact CB-CG2 4.36Å; I82-V305 HydrophobicContact CG2-CG1 3.67Å; I82-V305 HydrophobicContact CG2-CG2 4.47Å; I82-Y309 HydrophobicContact CG2-CE2 4.43Å; I82-Y309 PolarHBondContact O-OH 3.13Å
83	I	85.3	Confident	83.4	Confident	1 Å²	1	17.4 Å²	17.4	1%	0.005	12%	0.115	C	C	.	.	S	Bend	trans	-70.3	87.1	176.7	-58	-175.4	0	0	0	108.1	V79 K223 L224 L227 V305 V308 Y309	V79-I83 HydrophobicContact CG1-CD1 3.57Å; V79-I83 HydrophobicContact CG1-CG1 4.21Å; V79-I83 WeakPolarHBondContact O-CB 3.37Å; V79-I83 VanDerWaalsContact O-CG1 3.3Å; V79-I83 WeakPolarHBondContact O-CG1 3.29Å; V79-I83 PolarHBondContact O-N 3.43Å; I83-K223 VanDerWaalsContact O-CD 3.32Å; I83-K223 WeakPolarHBondContact O-CD 3.28Å; I83-K223 WeakPolarHBondContact O-CE 3.28Å; I83-K223 PolarHBondContact O-NZ 3.37Å; I83-L224 HydrophobicContact CD1-CD2 4.02Å; I83-L227 HydrophobicContact CG2-CD1 3.26Å; I83-V305 HydrophobicContact CD1-CG2 4.29Å; I83-V305 HydrophobicContact CG1-CG1 4.27Å; I83-V305 HydrophobicContact CG1-CG2 4.01Å; I83-V308 HydrophobicContact CD1-CG1 4.27Å; I83-Y309 WeakPolarHBondContact CA-OH 3.29Å; I83-Y309 HydrophobicContact CG1-CE1 4.11Å; I83-Y309 HydrophobicContact CG2-CE1 4.49Å
84	G	77.4	Confident	84	Confident	6 Å²	6	13.7 Å²	13.7	6%	0.062	10%	0.095	C	C	.	.	S	Bend	trans	-120	-146.8	-178.7	0	0	0	0	0	111.9	I82 G86	I82-G84 PolarHBondContact O-N 3.32Å; G84-G86 VanDerWaalsContact C-N 3.3Å
85	S	74.8	Confident	84.6	Confident	4 Å²	4	15 Å²	15	3%	0.028	10%	0.1	C	C	.	.	S	Bend	trans	-72.5	-21.1	175.4	54.9	0	0	0	0	113.8	I87 F88 V167 C355	S85-I87 VanDerWaalsContact C-N 3.33Å; S85-I87 PolarHBondContact O-N 2.85Å; S85-F88 WeakPolarHBondContact O-CB 3.27Å; S85-F88 PolarHBondContact O-N 2.9Å; S85-V167 WeakPolarHBondContact OG-CG1 3.41Å; S85-V167 WeakPolarHBondContact OG-CG2 3.39Å; S85-C355 WeakPolarHBondContact CB-SG 3.49Å
86	G	84.3	Confident	84.9	Confident	5 Å²	5	19.6 Å²	19.6	5%	0.052	12%	0.116	C	C	.	.	H	α-helix	trans	-55.7	-43.2	-173	0	0	0	0	0	113.6	G84 F88 V89 T90	G84-G86 VanDerWaalsContact C-N 3.3Å; G86-F88 PolarHBondContact O-N 2.82Å; G86-F88 VanDerWaalsContact O-N 3.09Å; G86-V89 PolarHBondContact O-N 3.38Å; G86-T90 WeakPolarHBondContact O-CG2 3.17Å; G86-T90 PolarHBondContact O-N 3.11Å; G86-T90 PolarHBondContact O-OG1 3.46Å
87	I	89.6	Confident	85.3	Confident	0 Å²	0	18.7 Å²	18.7	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-62.2	-18.9	179.9	-169.1	54.4	0	0	0	114.1	S85 P91 W108 L227 Y309 T312	S85-I87 VanDerWaalsContact C-N 3.33Å; S85-I87 PolarHBondContact O-N 2.85Å; I87-P91 WeakPolarHBondContact O-CD 3.48Å; I87-P91 WeakPolarHBondContact O-CG 3.05Å; I87-W108 HydrophobicContact CD1-CH2 3.46Å; I87-W108 VanDerWaalsContact CD1-CH2 3.46Å; I87-W108 HydrophobicContact CD1-CZ2 3.94Å; I87-W108 HydrophobicContact CD1-CZ3 3.9Å; I87-L227 HydrophobicContact CG1-CD2 4.44Å; I87-L227 HydrophobicContact CG2-CD2 4.14Å; I87-Y309 HydrophobicContact CB-CD1 4.08Å; I87-Y309 HydrophobicContact CB-CE1 3.69Å; I87-Y309 HydrophobicContact CD1-CD1 3.63Å; I87-Y309 HydrophobicContact CD1-CD2 4.41Å; I87-Y309 HydrophobicContact CD1-CE1 4.13Å; I87-Y309 HydrophobicContact CD1-CG 3.77Å; I87-Y309 HydrophobicContact CG1-CD1 3.7Å; I87-Y309 HydrophobicContact CG1-CE1 3.85Å; I87-Y309 HydrophobicContact CG1-CG 4.35Å; I87-Y309 HydrophobicContact CG2-CE1 4.23Å; I87-T312 HydrophobicContact CG1-CG2 4.15Å
88	F	86.1	Confident	85.9	Confident	2 Å²	2	16 Å²	16	1%	0.009	9%	0.087	C	C	.	.	H	α-helix	trans	-89.2	-13.1	178.4	-59.7	-62.5	0	0	0	112.5	S85 G86 Y174 L227 I230 A332 V351	S85-F88 WeakPolarHBondContact O-CB 3.27Å; S85-F88 PolarHBondContact O-N 2.9Å; G86-F88 PolarHBondContact O-N 2.82Å; G86-F88 VanDerWaalsContact O-N 3.09Å; F88-Y174 HydrophobicContact CB-CE2 4.17Å; F88-Y174 PolarHBondContact O-OH 2.98Å; F88-L227 HydrophobicContact CE1-CD2 3.99Å; F88-L227 HydrophobicContact CZ-CD2 3.92Å; F88-L227 HydrophobicContact CZ-CG 4.26Å; F88-I230 HydrophobicContact CE1-CD1 4.26Å; F88-A332 HydrophobicContact CD1-CB 3.81Å; F88-A332 HydrophobicContact CE1-CB 4.29Å; F88-V351 HydrophobicContact CB-CG1 4.01Å; F88-V351 HydrophobicContact CD1-CG1 4.29Å; F88-V351 HydrophobicContact CD1-CG2 3.72Å; F88-V351 HydrophobicContact CD2-CB 4.43Å; F88-V351 HydrophobicContact CD2-CG1 3.65Å; F88-V351 HydrophobicContact CD2-CG2 4.17Å; F88-V351 HydrophobicContact CE1-CG2 3.64Å; F88-V351 HydrophobicContact CE2-CG1 4.18Å; F88-V351 HydrophobicContact CE2-CG2 4.09Å; F88-V351 HydrophobicContact CG-CG1 3.7Å; F88-V351 HydrophobicContact CG-CG2 4Å; F88-V351 HydrophobicContact CZ-CG2 3.83Å
89	V	82.9	Confident	86.2	Confident	18 Å²	18	16.8 Å²	16.8	11%	0.109	10%	0.096	C	C	.	.	H	α-helix	trans	-114.9	-44.3	-171.4	-179.4	0	0	0	0	111.5	G86 V170	G86-V89 PolarHBondContact O-N 3.38Å; V89-V170 HydrophobicContact CB-CG2 4.38Å; V89-V170 HydrophobicContact CG1-CG2 4.3Å; V89-V170 HydrophobicContact CG2-CB 3.89Å; V89-V170 HydrophobicContact CG2-CG1 3.31Å; V89-V170 HydrophobicContact CG2-CG2 3.23Å
90	T	89.3	Confident	86.5	Confident	1 Å²	1	16 Å²	16	1%	0.006	9%	0.091	C	C	.	.	H	α-helix	trans	-74.9	-19.2	-170.9	64	0	0	0	0	115	G86 T92 G93 V94 W108 S269 F272 A273	G86-T90 WeakPolarHBondContact O-CG2 3.17Å; G86-T90 PolarHBondContact O-N 3.11Å; G86-T90 PolarHBondContact O-OG1 3.46Å; T90-T92 VanDerWaalsContact C-N 3.33Å; T90-T92 PolarHBondContact O-N 3.44Å; T90-G93 PolarHBondContact O-N 3.43Å; T90-V94 WeakPolarHBondContact O-CB 3.44Å; T90-V94 VanDerWaalsContact O-CG2 3.28Å; T90-V94 WeakPolarHBondContact O-CG2 3.34Å; T90-V94 PolarHBondContact O-N 3.16Å; T90-W108 WeakPolarHBondContact OG1-CH2 3.07Å; T90-W108 VanDerWaalsContact OG1-CZ2 3.27Å; T90-W108 WeakPolarHBondContact OG1-CZ2 3.5Å; T90-S269 WeakPolarHBondContact CB-O 3.42Å; T90-S269 WeakPolarHBondContact CG2-O 3.35Å; T90-F272 HydrophobicContact CG2-CB 4.42Å; T90-F272 HydrophobicContact CG2-CD1 3.79Å; T90-A273 HydrophobicContact CG2-CB 4.18Å; T90-A273 WeakPolarHBondContact OG1-CB 3.49Å
91	P	92.1	Very high	87.1	Confident	1 Å²	1	14.9 Å²	14.9	1%	0.006	8%	0.079	C	C	.	.	H	α-helix	trans	-53.3	-47	173.2	-29.7	36.9	0	0	0	113.4	I87 G93 V94 Y95 W108 N313 Y316 M325	I87-P91 WeakPolarHBondContact O-CD 3.48Å; I87-P91 WeakPolarHBondContact O-CG 3.05Å; P91-G93 PolarHBondContact O-N 2.99Å; P91-V94 PolarHBondContact O-N 3.46Å; P91-Y95 WeakPolarHBondContact O-CB 3.3Å; P91-Y95 PolarHBondContact O-N 3.06Å; P91-W108 HydrophobicContact CG-CZ2 4.16Å; P91-N313 WeakPolarHBondContact CB-OD1 3.27Å; P91-Y316 HydrophobicContact CB-CD2 4.28Å; P91-Y316 HydrophobicContact CB-CE2 4.47Å; P91-Y316 HydrophobicContact CG-CD2 4.2Å; P91-Y316 HydrophobicContact CG-CE2 3.94Å; P91-M325 HydrophobicContact CB-SD 4.46Å
92	T	89.8	Confident	87.8	Confident	7 Å²	7	12.6 Å²	12.6	4%	0.043	7%	0.067	C	C	.	.	H	α-helix	trans	-63.8	-41.8	177.5	-55.5	0	0	0	0	111.7	T90 R96 M325 V331	T90-T92 VanDerWaalsContact C-N 3.33Å; T90-T92 PolarHBondContact O-N 3.44Å; T92-R96 WeakPolarHBondContact O-CB 3.43Å; T92-R96 PolarHBondContact O-N 3.1Å; T92-M325 VanDerWaalsContact CG2-O 3.27Å; T92-M325 WeakPolarHBondContact CG2-O 3.35Å; T92-M325 PolarHBondContact OG1-O 2.97Å; T92-V331 WeakPolarHBondContact OG1-CG2 3.25Å
93	G	87.9	Confident	88.1	Confident	2 Å²	2	13.2 Å²	13.2	2%	0.021	7%	0.07	C	C	.	.	H	α-helix	trans	-65.5	-44.2	177.6	0	0	0	0	0	113	T90 P91 E97	T90-G93 PolarHBondContact O-N 3.43Å; P91-G93 PolarHBondContact O-N 2.99Å; G93-E97 WeakPolarHBondContact O-CG 3.32Å; G93-E97 PolarHBondContact O-N 3.18Å
94	V	91.9	Very high	88.5	Confident	0 Å²	0	13.2 Å²	13.2	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-62.1	-47.4	176.5	172.4	0	0	0	0	110.4	T90 P91 E97 A98 V107 W108	T90-V94 WeakPolarHBondContact O-CB 3.44Å; T90-V94 VanDerWaalsContact O-CG2 3.28Å; T90-V94 WeakPolarHBondContact O-CG2 3.34Å; T90-V94 PolarHBondContact O-N 3.16Å; P91-V94 PolarHBondContact O-N 3.46Å; V94-E97 PolarHBondContact O-N 3.44Å; V94-A98 WeakPolarHBondContact O-CB 3.28Å; V94-A98 PolarHBondContact O-N 3.3Å; V94-V107 HydrophobicContact CG1-CB 4.07Å; V94-V107 HydrophobicContact CG1-CG1 3.85Å; V94-W108 HydrophobicContact CG2-CZ2 4.41Å
95	Y	92.4	Very high	89.3	Confident	26 Å²	26	14.4 Å²	14.4	10%	0.102	8%	0.075	C	C	.	.	H	α-helix	trans	-68.9	-39.5	-178	-178.7	-98.1	0	0	0	113	P91 E97 A98 G99 V101 S104 F317 P322 M325 L326	P91-Y95 WeakPolarHBondContact O-CB 3.3Å; P91-Y95 PolarHBondContact O-N 3.06Å; Y95-E97 PolarHBondContact O-N 2.84Å; Y95-A98 PolarHBondContact O-N 2.93Å; Y95-G99 PolarHBondContact O-N 2.89Å; Y95-G99 PolarHBondContact OH-O 3.5Å; Y95-V101 HydrophobicContact CE2-CG2 4.11Å; Y95-S104 WeakPolarHBondContact CA-OG 3.33Å; Y95-S104 WeakPolarHBondContact CD2-OG 3.19Å; Y95-F317 AromaticContact CD2-CE1 3.76Å; Y95-F317 HydrophobicContact CD2-CE1 3.76Å; Y95-F317 AromaticContact CD2-CZ 3.97Å; Y95-F317 HydrophobicContact CD2-CZ 3.97Å; Y95-F317 HydrophobicContact CE2-CE1 4.27Å; Y95-F317 HydrophobicContact CG-CE1 4.36Å; Y95-P322 HydrophobicContact CE1-CB 3.64Å; Y95-P322 HydrophobicContact CE2-CB 4.09Å; Y95-P322 WeakPolarHBondContact OH-CB 3.31Å; Y95-M325 HydrophobicContact CD1-CE 3.54Å; Y95-M325 HydrophobicContact CD2-CE 3.79Å; Y95-M325 HydrophobicContact CE1-CE 4.46Å; Y95-M325 HydrophobicContact CG-CE 3.18Å; Y95-L326 HydrophobicContact CD1-CD1 4.22Å; Y95-L326 HydrophobicContact CD1-CD2 3.68Å; Y95-L326 HydrophobicContact CD1-CG 3.75Å; Y95-L326 HydrophobicContact CE1-CD1 3.82Å; Y95-L326 HydrophobicContact CE1-CD2 4.16Å; Y95-L326 HydrophobicContact CE1-CG 3.8Å
96	R	90.9	Very high	90.2	Very high	111 Å²	111	18 Å²	18	42%	0.419	9%	0.093	S	C	.	.	H	α-helix	trans	-54.3	-41.6	174.8	-177.2	-177.9	-64.6	138.8	-0.2	112.2	T92 L326 F414	T92-R96 WeakPolarHBondContact O-CB 3.43Å; T92-R96 PolarHBondContact O-N 3.1Å; R96-L326 HydrophobicContact CB-CD2 3.69Å; R96-L326 HydrophobicContact CG-CD2 4.21Å; R96-F414 VanDerWaalsContact NH1-CE2 3.33Å
97	E	90.1	Very high	90.7	Very high	44 Å²	44	18 Å²	18	21%	0.206	9%	0.092	C	C	.	.	H	α-helix	trans	-87.2	-31.6	-177.7	-62.6	-60.3	148.8	0	0	112.7	G93 V94 Y95 S257 N262 L265 A266	G93-E97 WeakPolarHBondContact O-CG 3.32Å; G93-E97 PolarHBondContact O-N 3.18Å; V94-E97 PolarHBondContact O-N 3.44Å; Y95-E97 PolarHBondContact O-N 2.84Å; E97-S257 WeakPolarHBondContact O-CB 3.35Å; E97-N262 HydrophobicContact CB-CB 4.5Å; E97-N262 WeakPolarHBondContact CB-O 3.31Å; E97-N262 WeakPolarHBondContact O-CB 3.43Å; E97-L265 HydrophobicContact CB-CB 4.45Å; E97-L265 HydrophobicContact CG-CB 3.82Å; E97-A266 HydrophobicContact CB-CB 3.75Å
98	A	91	Very high	91	Very high	1 Å²	1	18 Å²	18	1%	0.008	9%	0.092	C	C	.	.	H	α-helix	trans	-78.7	-32.2	178.1	0	0	0	0	0	113.1	V94 Y95 S100 L103 S104 S257	V94-A98 WeakPolarHBondContact O-CB 3.28Å; V94-A98 PolarHBondContact O-N 3.3Å; Y95-A98 PolarHBondContact O-N 2.93Å; A98-S100 PolarHBondContact O-N 2.95Å; A98-S100 VanDerWaalsContact O-N 3.12Å; A98-L103 HydrophobicContact CB-CB 4.23Å; A98-L103 HydrophobicContact CB-CD2 4.17Å; A98-L103 HydrophobicContact CB-CG 4.09Å; A98-L103 WeakPolarHBondContact O-CD2 3.4Å; A98-S104 WeakPolarHBondContact CB-OG 3.36Å; A98-S257 PolarHBondContact O-N 3.04Å
99	G	89.3	Confident	91.5	Very high	19 Å²	19	20.2 Å²	20.2	20%	0.196	11%	0.107	C	C	.	.			trans	74	-11.6	179.3	0	0	0	0	0	115.9	Y95 G255	Y95-G99 PolarHBondContact O-N 2.89Å; Y95-G99 PolarHBondContact OH-O 3.5Å; G99-G255 CarbonylContact C-O 3.48Å
100	S	90.9	Very high	92.1	Very high	1 Å²	1	22.7 Å²	22.7	1%	0.007	12%	0.123	C	C	.	.	S	Bend	trans	-140.7	155.9	178.5	75.7	0	0	0	0	113	A98 L103 S104 S252 K254 S256	A98-S100 PolarHBondContact O-N 2.95Å; A98-S100 VanDerWaalsContact O-N 3.12Å; S100-L103 WeakPolarHBondContact OG-CB 3.45Å; S100-L103 PolarHBondContact OG-N 3.29Å; S100-S104 WeakPolarHBondContact O-CB 3.32Å; S100-S104 PolarHBondContact O-N 2.71Å; S100-S104 PolarHBondContact O-OG 3.39Å; S100-S252 WeakPolarHBondContact CB-O 3.27Å; S100-K254 VanDerWaalsContact CB-O 3.27Å; S100-K254 WeakPolarHBondContact CB-O 3.39Å; S100-S256 VanDerWaalsContact CB-OG 3.26Å; S100-S256 WeakPolarHBondContact CB-OG 3.46Å; S100-S256 PolarHBondContact OG-OG 3.39Å
101	V	90.6	Very high	92.3	Very high	3 Å²	3	22.7 Å²	22.7	2%	0.018	12%	0.122	C	C	.	.	H	α-helix	trans	-65.8	-47.4	-178.4	176.1	0	0	0	0	110.7	Y95 S104 L105 E246 L247 S252 F317 P322	Y95-V101 HydrophobicContact CE2-CG2 4.11Å; V101-S104 WeakPolarHBondContact O-CB 3.33Å; V101-S104 PolarHBondContact O-N 2.7Å; V101-L105 HydrophobicContact CG1-CD1 4.43Å; V101-L105 WeakPolarHBondContact O-CG 3.42Å; V101-L105 PolarHBondContact O-N 3.37Å; V101-E246 HydrophobicContact CG2-CB 4.39Å; V101-L247 HydrophobicContact CG1-CD2 3.64Å; V101-S252 PolarHBondContact N-O 3.45Å; V101-F317 HydrophobicContact CB-CD1 4.32Å; V101-F317 HydrophobicContact CB-CE1 4.4Å; V101-F317 HydrophobicContact CB-CG 4.43Å; V101-F317 HydrophobicContact CG1-CB 3.86Å; V101-F317 HydrophobicContact CG1-CD1 3.87Å; V101-F317 HydrophobicContact CG1-CD2 3.57Å; V101-F317 HydrophobicContact CG1-CE1 4.23Å; V101-F317 HydrophobicContact CG1-CE2 3.99Å; V101-F317 HydrophobicContact CG1-CG 3.51Å; V101-F317 HydrophobicContact CG1-CZ 4.31Å; V101-F317 HydrophobicContact CG2-CD1 3.72Å; V101-F317 HydrophobicContact CG2-CE1 3.89Å; V101-F317 HydrophobicContact CG2-CG 4.23Å; V101-P322 HydrophobicContact CG2-CG 4.49Å
102	G	91	Very high	92.4	Very high	8 Å²	8	22.7 Å²	22.7	8%	0.082	12%	0.123	C	C	.	.	H	α-helix	trans	-62.5	-45.9	180	0	0	0	0	0	112.3	S104 L105 I106 S252	G102-S104 VanDerWaalsContact C-N 3.32Å; G102-S104 PolarHBondContact O-N 2.92Å; G102-L105 PolarHBondContact O-N 2.87Å; G102-I106 WeakPolarHBondContact O-CG1 3.45Å; G102-I106 PolarHBondContact O-N 3.43Å; G102-I106 VanDerWaalsContact O-N 3.1Å; G102-S252 WeakPolarHBondContact CA-O 2.96Å; G102-S252 PolarHBondContact N-O 3.44Å
103	L	91.9	Very high	92.6	Very high	18 Å²	18	27 Å²	27	9%	0.094	15%	0.149	C	C	.	.	H	α-helix	trans	-66	-37.1	177.1	-172.3	60.9	0	0	0	111.4	A98 S100 L105 I106 V107	A98-L103 HydrophobicContact CB-CB 4.23Å; A98-L103 HydrophobicContact CB-CD2 4.17Å; A98-L103 HydrophobicContact CB-CG 4.09Å; A98-L103 WeakPolarHBondContact O-CD2 3.4Å; S100-L103 WeakPolarHBondContact OG-CB 3.45Å; S100-L103 PolarHBondContact OG-N 3.29Å; L103-L105 PolarHBondContact O-N 3.16Å; L103-I106 PolarHBondContact O-N 3.21Å; L103-V107 WeakPolarHBondContact O-CG2 3.47Å; L103-V107 PolarHBondContact O-N 3.07Å
104	S	93.5	Very high	92.9	Very high	1 Å²	1	28 Å²	28	1%	0.007	15%	0.153	C	C	.	.	H	α-helix	trans	-59.5	-45.8	175.4	-61	0	0	0	0	112.2	Y95 A98 S100 V101 G102 I106 V107 W108	Y95-S104 WeakPolarHBondContact CA-OG 3.33Å; Y95-S104 WeakPolarHBondContact CD2-OG 3.19Å; A98-S104 WeakPolarHBondContact CB-OG 3.36Å; S100-S104 WeakPolarHBondContact O-CB 3.32Å; S100-S104 PolarHBondContact O-N 2.71Å; S100-S104 PolarHBondContact O-OG 3.39Å; V101-S104 WeakPolarHBondContact O-CB 3.33Å; V101-S104 PolarHBondContact O-N 2.7Å; G102-S104 VanDerWaalsContact C-N 3.32Å; G102-S104 PolarHBondContact O-N 2.92Å; S104-I106 VanDerWaalsContact C-N 3.34Å; S104-I106 PolarHBondContact O-N 3.23Å; S104-V107 WeakPolarHBondContact O-CB 3.34Å; S104-V107 PolarHBondContact O-N 3.24Å; S104-W108 PolarHBondContact O-N 3.35Å
105	L	94.1	Very high	93	Very high	31 Å²	31	28 Å²	28	16%	0.162	15%	0.153	C	C	.	.	H	α-helix	trans	-65.5	-35.5	177.3	-66.9	174.8	0	0	0	112.5	V101 G102 L103 W108 S109 L247 V310 N313 L314 F317	V101-L105 HydrophobicContact CG1-CD1 4.43Å; V101-L105 WeakPolarHBondContact O-CG 3.42Å; V101-L105 PolarHBondContact O-N 3.37Å; G102-L105 PolarHBondContact O-N 2.87Å; L103-L105 PolarHBondContact O-N 3.16Å; L105-W108 PolarHBondContact O-N 3.43Å; L105-S109 PolarHBondContact O-N 3.13Å; L105-S109 VanDerWaalsContact O-N 3.09Å; L105-S109 PolarHBondContact O-OG 2.93Å; L105-L247 HydrophobicContact CD1-CD2 4.41Å; L105-V310 HydrophobicContact CD2-CG1 4.43Å; L105-N313 HydrophobicContact CD2-CB 3.9Å; L105-L314 HydrophobicContact CD1-CD1 4.36Å; L105-F317 HydrophobicContact CD2-CD2 4.21Å; L105-F317 HydrophobicContact CD2-CE2 4.15Å; L105-F317 HydrophobicContact CG-CD2 4.42Å; L105-F317 HydrophobicContact CG-CE2 4.29Å
106	I	95	Very high	93	Very high	79 Å²	79	28.2 Å²	28.2	41%	0.405	16%	0.156	S	C	.	.	H	α-helix	trans	-63.2	-47.3	172	-68.1	171.9	0	0	0	110.2	G102 L103 S104 W108 S109 V110 F253	G102-I106 WeakPolarHBondContact O-CG1 3.45Å; G102-I106 PolarHBondContact O-N 3.43Å; G102-I106 VanDerWaalsContact O-N 3.1Å; L103-I106 PolarHBondContact O-N 3.21Å; S104-I106 VanDerWaalsContact C-N 3.34Å; S104-I106 PolarHBondContact O-N 3.23Å; I106-W108 VanDerWaalsContact C-N 3.32Å; I106-W108 PolarHBondContact O-N 3.07Å; I106-S109 WeakPolarHBondContact O-CB 3.29Å; I106-S109 PolarHBondContact O-N 3.17Å; I106-S109 VanDerWaalsContact O-N 3.1Å; I106-V110 HydrophobicContact CG2-CG2 4.02Å; I106-V110 WeakPolarHBondContact O-CB 3.48Å; I106-V110 VanDerWaalsContact O-CG2 3.31Å; I106-V110 WeakPolarHBondContact O-CG2 3.42Å; I106-V110 PolarHBondContact O-N 3.3Å; I106-F253 HydrophobicContact CD1-CE1 3.7Å; I106-F253 HydrophobicContact CD1-CZ 3.95Å
107	V	94.8	Very high	93.1	Very high	6 Å²	6	24.1 Å²	24.1	4%	0.036	14%	0.144	C	C	.	.	H	α-helix	trans	-55.9	-47.9	177.6	169.4	0	0	0	0	110.4	V94 L103 S104 S109 V110 C111 A266 L267	V94-V107 HydrophobicContact CG1-CB 4.07Å; V94-V107 HydrophobicContact CG1-CG1 3.85Å; L103-V107 WeakPolarHBondContact O-CG2 3.47Å; L103-V107 PolarHBondContact O-N 3.07Å; S104-V107 WeakPolarHBondContact O-CB 3.34Å; S104-V107 PolarHBondContact O-N 3.24Å; V107-S109 VanDerWaalsContact C-N 3.3Å; V107-S109 PolarHBondContact O-N 3.01Å; V107-V110 PolarHBondContact O-N 3.46Å; V107-C111 WeakPolarHBondContact O-CB 3.46Å; V107-C111 PolarHBondContact O-N 2.92Å; V107-C111 PolarHBondContact O-SG 3.46Å; V107-A266 HydrophobicContact CG1-CB 4.19Å; V107-A266 HydrophobicContact CG2-CB 4.29Å; V107-L267 HydrophobicContact CG1-CD2 4.2Å
108	W	95.8	Very high	93.2	Very high	0 Å²	0	22 Å²	22	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-58.1	-40.2	176.5	-83	106.4	0	0	0	113.5	I87 T90 P91 V94 S104 L105 I106 G112 A273 Y274 Y309 V310 N313	I87-W108 HydrophobicContact CD1-CH2 3.46Å; I87-W108 VanDerWaalsContact CD1-CH2 3.46Å; I87-W108 HydrophobicContact CD1-CZ2 3.94Å; I87-W108 HydrophobicContact CD1-CZ3 3.9Å; T90-W108 WeakPolarHBondContact OG1-CH2 3.07Å; T90-W108 VanDerWaalsContact OG1-CZ2 3.27Å; T90-W108 WeakPolarHBondContact OG1-CZ2 3.5Å; P91-W108 HydrophobicContact CG-CZ2 4.16Å; V94-W108 HydrophobicContact CG2-CZ2 4.41Å; S104-W108 PolarHBondContact O-N 3.35Å; L105-W108 PolarHBondContact O-N 3.43Å; I106-W108 VanDerWaalsContact C-N 3.32Å; I106-W108 PolarHBondContact O-N 3.07Å; W108-G112 PolarHBondContact O-N 3.42Å; W108-A273 HydrophobicContact CH2-CB 3.6Å; W108-A273 HydrophobicContact CZ3-CB 3.73Å; W108-Y274 HydrophobicContact CE3-CD2 4.47Å; W108-Y274 AromaticContact CE3-CE2 3.59Å; W108-Y274 HydrophobicContact CE3-CE2 3.59Å; W108-Y274 HydrophobicContact CZ3-CD2 4.42Å; W108-Y274 AromaticContact CZ3-CE2 3.92Å; W108-Y274 HydrophobicContact CZ3-CE2 3.92Å; W108-Y274 WeakPolarHBondContact O-CE2 3.47Å; W108-Y274 PolarHBondContact O-OH 3.34Å; W108-Y309 AromaticContact CE3-CD2 3.85Å; W108-Y309 HydrophobicContact CE3-CD2 3.85Å; W108-Y309 HydrophobicContact CE3-CG 4.22Å; W108-Y309 HydrophobicContact CH2-CD2 4.38Å; W108-Y309 AromaticContact CZ3-CD2 3.36Å; W108-Y309 HydrophobicContact CZ3-CD2 3.36Å; W108-Y309 AromaticContact CZ3-CE2 3.97Å; W108-Y309 HydrophobicContact CZ3-CE2 3.97Å; W108-Y309 AromaticContact CZ3-CG 3.87Å; W108-Y309 HydrophobicContact CZ3-CG 3.87Å; W108-V310 HydrophobicContact CB-CG2 4.11Å; W108-N313 WeakPolarHBondContact CZ2-ND2 3.41Å; W108-N313 PolarHBondContact NE1-ND2 3.46Å; W108-N313 PolarHBondContact NE1-OD1 3.25Å
109	S	96.1	Very high	93.2	Very high	47 Å²	47	22 Å²	22	33%	0.329	13%	0.134	S	C	.	.	H	α-helix	trans	-69.5	-44.2	178.1	-57.3	0	0	0	0	111.5	L105 I106 V107 G112 V113	L105-S109 PolarHBondContact O-N 3.13Å; L105-S109 VanDerWaalsContact O-N 3.09Å; L105-S109 PolarHBondContact O-OG 2.93Å; I106-S109 WeakPolarHBondContact O-CB 3.29Å; I106-S109 PolarHBondContact O-N 3.17Å; I106-S109 VanDerWaalsContact O-N 3.1Å; V107-S109 VanDerWaalsContact C-N 3.3Å; V107-S109 PolarHBondContact O-N 3.01Å; S109-G112 PolarHBondContact O-N 3.02Å; S109-V113 WeakPolarHBondContact O-CG2 3.47Å; S109-V113 PolarHBondContact O-N 3.1Å
110	V	95.2	Very high	93.4	Very high	71 Å²	71	22.8 Å²	22.8	43%	0.43	13%	0.133	S	C	.	.	H	α-helix	trans	-62.7	-42.6	177.2	170.7	0	0	0	0	110.9	I106 V107 G112 V113 F114 L267	I106-V110 HydrophobicContact CG2-CG2 4.02Å; I106-V110 WeakPolarHBondContact O-CB 3.48Å; I106-V110 VanDerWaalsContact O-CG2 3.31Å; I106-V110 WeakPolarHBondContact O-CG2 3.42Å; I106-V110 PolarHBondContact O-N 3.3Å; V107-V110 PolarHBondContact O-N 3.46Å; V110-G112 VanDerWaalsContact C-N 3.29Å; V110-G112 PolarHBondContact O-N 3.04Å; V110-V113 PolarHBondContact O-N 3.28Å; V110-F114 WeakPolarHBondContact O-CB 3.42Å; V110-F114 PolarHBondContact O-N 3.48Å; V110-L267 HydrophobicContact CG1-CD2 4.02Å
111	C	94.3	Very high	93.4	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-58.7	-39.9	174.8	-68.9	0	0	0	0	112.4	V107 S115 L271 Y274	V107-C111 WeakPolarHBondContact O-CB 3.46Å; V107-C111 PolarHBondContact O-N 2.92Å; V107-C111 PolarHBondContact O-SG 3.46Å; C111-S115 VanDerWaalsContact O-CB 3.32Å; C111-S115 WeakPolarHBondContact O-CB 3.4Å; C111-S115 PolarHBondContact O-N 3.06Å; C111-S115 PolarHBondContact O-OG 3.12Å; C111-L271 HydrophobicContact CB-CD2 3.84Å; C111-L271 HydrophobicContact CB-CG 4.28Å; C111-Y274 HydrophobicContact CB-CD2 3.52Å; C111-Y274 HydrophobicContact CB-CE2 3.43Å; C111-Y274 VanDerWaalsContact CB-CE2 3.43Å
112	G	94.4	Very high	93.4	Very high	1 Å²	1	22.7 Å²	22.7	1%	0.01	13%	0.133	C	C	.	.	H	α-helix	trans	-66.1	-46.4	176.5	0	0	0	0	0	113.2	W108 S109 V110 S115 T116 T306	W108-G112 PolarHBondContact O-N 3.42Å; S109-G112 PolarHBondContact O-N 3.02Å; V110-G112 VanDerWaalsContact C-N 3.29Å; V110-G112 PolarHBondContact O-N 3.04Å; G112-S115 PolarHBondContact O-N 3.42Å; G112-T116 PolarHBondContact O-N 3.2Å; G112-T116 PolarHBondContact O-OG1 2.89Å; G112-T306 VanDerWaalsContact CA-OG1 3.32Å; G112-T306 WeakPolarHBondContact CA-OG1 3.42Å
113	V	94.4	Very high	93.3	Very high	97 Å²	97	22.3 Å²	22.3	59%	0.588	13%	0.129	S	C	*	.	H	α-helix	trans	-61.7	-47	174.9	174.4	0	0	0	0	110.5	S109 V110 S115 T116 V117	S109-V113 WeakPolarHBondContact O-CG2 3.47Å; S109-V113 PolarHBondContact O-N 3.1Å; V110-V113 PolarHBondContact O-N 3.28Å; V113-S115 PolarHBondContact O-N 3.36Å; V113-T116 WeakPolarHBondContact O-CB 3.46Å; V113-T116 PolarHBondContact O-N 3.1Å; V113-T116 VanDerWaalsContact O-N 3.1Å; V113-V117 WeakPolarHBondContact O-CG2 3.48Å; V113-V117 PolarHBondContact O-N 3.33Å
114	F	93.3	Very high	93.2	Very high	25 Å²	25	21.5 Å²	21.5	11%	0.11	13%	0.125	C	C	.	.	H	α-helix	trans	-59.4	-46	178.7	178.7	-99	0	0	0	111.8	V110 T116 V117 G118 L271 W425 F459 A462 L466	V110-F114 WeakPolarHBondContact O-CB 3.42Å; V110-F114 PolarHBondContact O-N 3.48Å; F114-T116 VanDerWaalsContact C-N 3.25Å; F114-T116 PolarHBondContact O-N 3.45Å; F114-V117 PolarHBondContact O-N 3.29Å; F114-G118 PolarHBondContact O-N 3.3Å; F114-L271 HydrophobicContact CD1-CD1 4.01Å; F114-L271 HydrophobicContact CD1-CD2 3.44Å; F114-L271 VanDerWaalsContact CD1-CD2 3.44Å; F114-L271 HydrophobicContact CD1-CG 4.39Å; F114-L271 HydrophobicContact CE1-CD1 3.88Å; F114-L271 HydrophobicContact CE1-CD2 4.03Å; F114-L271 HydrophobicContact CG-CD2 4.39Å; F114-W425 HydrophobicContact CD1-CH2 4.24Å; F114-W425 HydrophobicContact CD1-CZ3 4.48Å; F114-W425 HydrophobicContact CE1-CE3 4.12Å; F114-W425 AromaticContact CE1-CH2 3.53Å; F114-W425 HydrophobicContact CE1-CH2 3.53Å; F114-W425 HydrophobicContact CE1-CZ2 4.25Å; F114-W425 AromaticContact CE1-CZ3 3.43Å; F114-W425 HydrophobicContact CE1-CZ3 3.43Å; F114-W425 VanDerWaalsContact CE1-CZ3 3.43Å; F114-W425 HydrophobicContact CZ-CE3 4.38Å; F114-W425 HydrophobicContact CZ-CH2 4.5Å; F114-W425 AromaticContact CZ-CZ3 3.99Å; F114-W425 HydrophobicContact CZ-CZ3 3.99Å; F114-F459 AromaticContact CD1-CE2 3.85Å; F114-F459 HydrophobicContact CD1-CE2 3.85Å; F114-F459 AromaticContact CD2-CD2 3.82Å; F114-F459 HydrophobicContact CD2-CD2 3.82Å; F114-F459 AromaticContact CD2-CE2 3.96Å; F114-F459 HydrophobicContact CD2-CE2 3.96Å; F114-F459 HydrophobicContact CE1-CD2 4.28Å; F114-F459 AromaticContact CE1-CE2 3.53Å; F114-F459 HydrophobicContact CE1-CE2 3.53Å; F114-F459 AromaticContact CE1-CZ 3.97Å; F114-F459 HydrophobicContact CE1-CZ 3.97Å; F114-F459 AromaticContact CE2-CD2 3.41Å; F114-F459 HydrophobicContact CE2-CD2 3.41Å; F114-F459 VanDerWaalsContact CE2-CD2 3.41Å; F114-F459 AromaticContact CE2-CE2 3.53Å; F114-F459 HydrophobicContact CE2-CE2 3.53Å; F114-F459 HydrophobicContact CE2-CG 4.14Å; F114-F459 HydrophobicContact CE2-CZ 4.37Å; F114-F459 HydrophobicContact CG-CD2 4.37Å; F114-F459 HydrophobicContact CG-CE2 4.11Å; F114-F459 AromaticContact CZ-CD2 3.71Å; F114-F459 HydrophobicContact CZ-CD2 3.71Å; F114-F459 HydrophobicContact CZ-CE1 4.44Å; F114-F459 AromaticContact CZ-CE2 3.35Å; F114-F459 HydrophobicContact CZ-CE2 3.35Å; F114-F459 HydrophobicContact CZ-CG 4.41Å; F114-F459 AromaticContact CZ-CZ 3.81Å; F114-F459 HydrophobicContact CZ-CZ 3.81Å; F114-F459 VanDerWaalsContact O-CE2 3.27Å; F114-F459 WeakPolarHBondContact O-CE2 3.28Å; F114-A462 HydrophobicContact CD2-CB 3.99Å; F114-A462 HydrophobicContact CE2-CB 3.38Å; F114-A462 HydrophobicContact CZ-CB 4.26Å; F114-L466 HydrophobicContact CZ-CD1 4.47Å
115	S	93.4	Very high	93	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-61.8	-34.6	176	-59.8	0	0	0	0	112.2	C111 G112 V113 G118 A119 Y274	C111-S115 VanDerWaalsContact O-CB 3.32Å; C111-S115 WeakPolarHBondContact O-CB 3.4Å; C111-S115 PolarHBondContact O-N 3.06Å; C111-S115 PolarHBondContact O-OG 3.12Å; G112-S115 PolarHBondContact O-N 3.42Å; V113-S115 PolarHBondContact O-N 3.36Å; S115-G118 PolarHBondContact O-N 3.19Å; S115-A119 VanDerWaalsContact O-CB 3.29Å; S115-A119 WeakPolarHBondContact O-CB 3.15Å; S115-A119 PolarHBondContact O-N 3.38Å; S115-Y274 WeakPolarHBondContact OG-CB 3.23Å
116	T	93	Very high	92.5	Very high	29 Å²	29	20.1 Å²	20.1	18%	0.178	12%	0.117	C	C	.	.	H	α-helix	trans	-65.3	-44.7	175.7	-53.5	0	0	0	0	112	G112 V113 F114 A119 L120 L302	G112-T116 PolarHBondContact O-N 3.2Å; G112-T116 PolarHBondContact O-OG1 2.89Å; V113-T116 WeakPolarHBondContact O-CB 3.46Å; V113-T116 PolarHBondContact O-N 3.1Å; V113-T116 VanDerWaalsContact O-N 3.1Å; F114-T116 VanDerWaalsContact C-N 3.25Å; F114-T116 PolarHBondContact O-N 3.45Å; T116-A119 PolarHBondContact O-N 2.92Å; T116-L120 HydrophobicContact CG2-CD1 4.35Å; T116-L120 VanDerWaalsContact O-CG 3.31Å; T116-L120 WeakPolarHBondContact O-CG 3.37Å; T116-L120 PolarHBondContact O-N 2.94Å; T116-L302 VanDerWaalsContact CA-CD1 3.41Å; T116-L302 HydrophobicContact CG2-CD1 4.41Å; T116-L302 WeakPolarHBondContact OG1-CB 3.33Å
117	V	93.3	Very high	92.1	Very high	26 Å²	26	16.6 Å²	16.6	16%	0.158	10%	0.1	C	C	.	.	H	α-helix	trans	-61.8	-45.3	175.2	178.9	0	0	0	0	110.8	V113 F114 L120 C121 L455 F459	V113-V117 WeakPolarHBondContact O-CG2 3.48Å; V113-V117 PolarHBondContact O-N 3.33Å; F114-V117 PolarHBondContact O-N 3.29Å; V117-L120 PolarHBondContact O-N 2.94Å; V117-C121 PolarHBondContact O-N 3.42Å; V117-C121 VanDerWaalsContact O-N 3.09Å; V117-C121 PolarHBondContact O-SG 3.41Å; V117-L455 HydrophobicContact CG1-CB 4.02Å; V117-L455 HydrophobicContact CG1-CD2 4.16Å; V117-L455 HydrophobicContact CG2-CD2 4.33Å; V117-F459 HydrophobicContact CB-CD2 4.25Å; V117-F459 HydrophobicContact CG1-CB 3.98Å; V117-F459 HydrophobicContact CG1-CD2 4.17Å; V117-F459 HydrophobicContact CG1-CG 4.46Å
118	G	92.2	Very high	91.7	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-59.5	-47.9	177.2	0	0	0	0	0	112.9	F114 S115 L120 C121 Y122	F114-G118 PolarHBondContact O-N 3.3Å; S115-G118 PolarHBondContact O-N 3.19Å; G118-L120 VanDerWaalsContact C-N 3.35Å; G118-L120 PolarHBondContact O-N 2.79Å; G118-C121 WeakPolarHBondContact O-CB 3.48Å; G118-C121 PolarHBondContact O-N 3.5Å; G118-Y122 WeakPolarHBondContact O-CD2 3.42Å; G118-Y122 PolarHBondContact O-N 3.15Å
119	A	91.9	Very high	91.1	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-63.4	-38.6	179.6	0	0	0	0	0	112.5	S115 T116 Y122 A123 W277 I298 L302	S115-A119 VanDerWaalsContact O-CB 3.29Å; S115-A119 WeakPolarHBondContact O-CB 3.15Å; S115-A119 PolarHBondContact O-N 3.38Å; T116-A119 PolarHBondContact O-N 2.92Å; A119-Y122 CarbonylContact O-C 2.99Å; A119-Y122 WeakPolarHBondContact O-CB 3.24Å; A119-Y122 PolarHBondContact O-N 3.41Å; A119-A123 PolarHBondContact O-N 2.96Å; A119-W277 VanDerWaalsContact CA-CE3 3.47Å; A119-W277 HydrophobicContact CB-CB 4.24Å; A119-W277 HydrophobicContact CB-CD2 4.11Å; A119-W277 HydrophobicContact CB-CE3 3.66Å; A119-W277 HydrophobicContact CB-CG 4.36Å; A119-W277 HydrophobicContact CB-CZ3 4.36Å; A119-I298 HydrophobicContact CB-CD1 4.24Å; A119-I298 HydrophobicContact CB-CG1 4.32Å; A119-I298 HydrophobicContact CB-CG2 3.45Å; A119-I298 VanDerWaalsContact CB-CG2 3.45Å; A119-L302 HydrophobicContact CB-CD1 3.53Å
120	L	91.9	Very high	90	Very high	35 Å²	35	19.5 Å²	19.5	18%	0.183	12%	0.118	C	C	.	.	H	α-helix	trans	-64.5	-39.7	174.2	-72.8	172.3	0	0	0	112.5	T116 V117 G118 Y122 A123 E124 I298 I299 V451	T116-L120 HydrophobicContact CG2-CD1 4.35Å; T116-L120 VanDerWaalsContact O-CG 3.31Å; T116-L120 WeakPolarHBondContact O-CG 3.37Å; T116-L120 PolarHBondContact O-N 2.94Å; V117-L120 PolarHBondContact O-N 2.94Å; G118-L120 VanDerWaalsContact C-N 3.35Å; G118-L120 PolarHBondContact O-N 2.79Å; L120-Y122 VanDerWaalsContact C-N 3.27Å; L120-Y122 PolarHBondContact O-N 3.35Å; L120-A123 WeakPolarHBondContact O-CB 3.4Å; L120-A123 PolarHBondContact O-N 2.74Å; L120-E124 PolarHBondContact O-N 2.92Å; L120-I298 HydrophobicContact CD2-CG2 4.36Å; L120-I298 HydrophobicContact CG-CG2 4.45Å; L120-I299 HydrophobicContact CD2-CD1 4.13Å; L120-I299 HydrophobicContact CD2-CG1 3.95Å; L120-V451 HydrophobicContact CB-CG1 4.33Å
121	C	92.1	Very high	88.9	Confident	1 Å²	1	21.7 Å²	21.7	1%	0.007	12%	0.122	C	C	.	.	H	α-helix	trans	-61.7	-41.2	173.5	-63.3	0	0	0	0	110.9	V117 G118 A123 E124 L125 I432 M435	V117-C121 PolarHBondContact O-N 3.42Å; V117-C121 VanDerWaalsContact O-N 3.09Å; V117-C121 PolarHBondContact O-SG 3.41Å; G118-C121 WeakPolarHBondContact O-CB 3.48Å; G118-C121 PolarHBondContact O-N 3.5Å; C121-A123 VanDerWaalsContact C-N 3.35Å; C121-E124 PolarHBondContact O-N 3.18Å; C121-L125 PolarHBondContact O-N 3.45Å; C121-I432 HydrophobicContact CB-CD1 4.08Å; C121-I432 HydrophobicContact CB-CG1 4.31Å; C121-M435 HydrophobicContact CB-CE 3.79Å; C121-M435 WeakPolarHBondContact O-CE 3.16Å
122	Y	90.2	Very high	87.5	Confident	1 Å²	1	23.5 Å²	23.5	0%	0.004	13%	0.134	C	C	.	.	H	α-helix	trans	-67.5	-32.5	176	-98.6	-97.8	0	0	0	113.8	G118 A119 L120 E124 L125 G126 D135 Y138 W277 N278 N281 I428 A431 I432	G118-Y122 WeakPolarHBondContact O-CD2 3.42Å; G118-Y122 PolarHBondContact O-N 3.15Å; A119-Y122 CarbonylContact O-C 2.99Å; A119-Y122 WeakPolarHBondContact O-CB 3.24Å; A119-Y122 PolarHBondContact O-N 3.41Å; L120-Y122 VanDerWaalsContact C-N 3.27Å; L120-Y122 PolarHBondContact O-N 3.35Å; Y122-E124 VanDerWaalsContact C-N 3.32Å; Y122-E124 PolarHBondContact O-N 3.25Å; Y122-L125 PolarHBondContact O-N 3.44Å; Y122-L125 VanDerWaalsContact O-N 3.12Å; Y122-G126 PolarHBondContact O-N 2.83Å; Y122-D135 WeakPolarHBondContact CE1-OD1 3.22Å; Y122-D135 PolarHBondContact OH-OD1 3.03Å; Y122-Y138 HydrophobicContact CD1-CE2 4.07Å; Y122-Y138 HydrophobicContact CE1-CD2 4.26Å; Y122-Y138 HydrophobicContact CE1-CE2 4.01Å; Y122-W277 HydrophobicContact CD1-CZ3 4.44Å; Y122-W277 AromaticContact CD2-CH2 3.71Å; Y122-W277 HydrophobicContact CD2-CH2 3.71Å; Y122-W277 AromaticContact CD2-CZ3 3.41Å; Y122-W277 HydrophobicContact CD2-CZ3 3.41Å; Y122-W277 VanDerWaalsContact CD2-CZ3 3.41Å; Y122-W277 AromaticContact CE2-CH2 3.84Å; Y122-W277 HydrophobicContact CE2-CH2 3.84Å; Y122-W277 AromaticContact CE2-CZ3 3.94Å; Y122-W277 HydrophobicContact CE2-CZ3 3.94Å; Y122-W277 HydrophobicContact CG-CH2 4.4Å; Y122-W277 AromaticContact CG-CZ3 3.67Å; Y122-W277 HydrophobicContact CG-CZ3 3.67Å; Y122-N278 HydrophobicContact CD1-CB 4.23Å; Y122-N278 HydrophobicContact CE1-CB 4.21Å; Y122-N281 PolarHBondContact O-OD1 3.46Å; Y122-I428 HydrophobicContact CE2-CG2 4.18Å; Y122-A431 WeakPolarHBondContact OH-CB 3.3Å; Y122-I432 HydrophobicContact CD2-CD1 4.16Å; Y122-I432 HydrophobicContact CD2-CG1 4.25Å; Y122-I432 HydrophobicContact CE2-CD1 3.98Å; Y122-I432 HydrophobicContact CE2-CG1 3.97Å
123	A	89.2	Confident	86.3	Confident	1 Å²	1	23.6 Å²	23.6	1%	0.008	14%	0.136	C	C	.	.	H	α-helix	trans	-62.9	-38.5	175.6	0	0	0	0	0	112.1	A119 L120 C121 T127 L294 I298	A119-A123 PolarHBondContact O-N 2.96Å; L120-A123 WeakPolarHBondContact O-CB 3.4Å; L120-A123 PolarHBondContact O-N 2.74Å; C121-A123 VanDerWaalsContact C-N 3.35Å; A123-T127 WeakPolarHBondContact O-CB 3.35Å; A123-T127 WeakPolarHBondContact O-CG2 3.47Å; A123-T127 PolarHBondContact O-N 3.46Å; A123-T127 VanDerWaalsContact O-N 3.1Å; A123-T127 PolarHBondContact O-OG1 3.24Å; A123-L294 HydrophobicContact CB-CD2 3.99Å; A123-L294 HydrophobicContact CB-CG 4.14Å; A123-I298 HydrophobicContact CB-CD1 3.77Å
124	E	90.2	Very high	85.6	Confident	0 Å²	0	19 Å²	19	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64	-44.1	170.4	165.8	168.4	164	0	0	111.5	L120 C121 Y122 T127 T128 M435 R439 R447 I449 K450 V451	L120-E124 PolarHBondContact O-N 2.92Å; C121-E124 PolarHBondContact O-N 3.18Å; Y122-E124 VanDerWaalsContact C-N 3.32Å; Y122-E124 PolarHBondContact O-N 3.25Å; E124-T127 WeakPolarHBondContact CA-OG1 3.42Å; E124-T127 PolarHBondContact O-N 3.36Å; E124-T127 PolarHBondContact O-OG1 3.16Å; E124-T127 VanDerWaalsContact O-OG1 3.12Å; E124-T128 WeakPolarHBondContact O-CB 3.3Å; E124-T128 PolarHBondContact O-N 2.9Å; E124-T128 PolarHBondContact O-OG1 2.85Å; E124-M435 HydrophobicContact CB-CE 4.02Å; E124-M435 HydrophobicContact CG-CE 4.04Å; E124-R439 IonicContact OE1-CZ 3.58Å; E124-R439 IonicContact OE1-NE 2.98Å; E124-R439 PolarHBondContact OE1-NE 3.29Å; E124-R439 IonicContact OE1-NH2 3.33Å; E124-R439 PolarHBondContact OE1-NH2 3.24Å; E124-R439 IonicContact OE2-CZ 2.93Å; E124-R439 IonicContact OE2-NE 2.6Å; E124-R439 IonicContact OE2-NH2 3.67Å; E124-R439 PolarHBondContact OE2-NH2 3.44Å; E124-R447 IonicContact OE1-NH1 2.76Å; E124-R447 PolarHBondContact OE1-NH1 3.1Å; E124-I449 HydrophobicContact CB-CG2 4.46Å; E124-I449 VanDerWaalsContact CG-O 3.29Å; E124-I449 WeakPolarHBondContact CG-O 3.43Å; E124-K450 WeakPolarHBondContact OE2-CA 3.39Å; E124-V451 WeakPolarHBondContact OE2-CG2 3.1Å; E124-V451 PolarHBondContact OE2-N 3.31Å
125	L	88	Confident	85.1	Confident	2 Å²	2	18 Å²	18	1%	0.01	10%	0.104	C	C	.	.	H	α-helix	trans	-64.2	-44.2	-178.8	-163.6	58.5	0	0	0	112	C121 Y122 T127 T128 I129 Y138 A431 M435	C121-L125 PolarHBondContact O-N 3.45Å; Y122-L125 PolarHBondContact O-N 3.44Å; Y122-L125 VanDerWaalsContact O-N 3.12Å; L125-T127 VanDerWaalsContact C-N 3.33Å; L125-T127 PolarHBondContact O-N 3.48Å; L125-T128 PolarHBondContact O-N 3.09Å; L125-I129 HydrophobicContact CD1-CD1 3.99Å; L125-I129 PolarHBondContact O-N 2.63Å; L125-Y138 HydrophobicContact CB-CE2 4.35Å; L125-Y138 HydrophobicContact CD1-CG 4.45Å; L125-Y138 HydrophobicContact CD2-CD1 4.34Å; L125-Y138 HydrophobicContact CD2-CD2 3.23Å; L125-Y138 HydrophobicContact CD2-CE2 3.81Å; L125-Y138 HydrophobicContact CD2-CG 3.54Å; L125-Y138 HydrophobicContact CG-CD1 3.94Å; L125-Y138 HydrophobicContact CG-CD2 3.65Å; L125-Y138 HydrophobicContact CG-CE1 4.22Å; L125-Y138 HydrophobicContact CG-CE2 3.92Å; L125-Y138 HydrophobicContact CG-CG 3.65Å; L125-A431 HydrophobicContact CD2-CB 4.42Å; L125-M435 HydrophobicContact CD1-CB 3.89Å; L125-M435 HydrophobicContact CD1-CG 4.05Å
126	G	84.4	Confident	84.8	Confident	1 Å²	1	18.1 Å²	18.1	1%	0.01	10%	0.104	C	C	.	.	H	α-helix	trans	-72.9	-20	178.1	0	0	0	0	0	115	Y122 Y138	Y122-G126 PolarHBondContact O-N 2.83Å; G126-Y138 WeakPolarHBondContact CA-OH 3.48Å; G126-Y138 PolarHBondContact N-OH 2.86Å
127	T	85.8	Confident	84.4	Confident	5 Å²	5	17 Å²	17	3%	0.031	10%	0.099	C	C	.	.	H	α-helix	trans	-88.3	-21.4	170.5	49.4	0	0	0	0	113.3	A123 E124 L125 Y291 L294 I449	A123-T127 WeakPolarHBondContact O-CB 3.35Å; A123-T127 WeakPolarHBondContact O-CG2 3.47Å; A123-T127 PolarHBondContact O-N 3.46Å; A123-T127 VanDerWaalsContact O-N 3.1Å; A123-T127 PolarHBondContact O-OG1 3.24Å; E124-T127 WeakPolarHBondContact CA-OG1 3.42Å; E124-T127 PolarHBondContact O-N 3.36Å; E124-T127 PolarHBondContact O-OG1 3.16Å; E124-T127 VanDerWaalsContact O-OG1 3.12Å; L125-T127 VanDerWaalsContact C-N 3.33Å; L125-T127 PolarHBondContact O-N 3.48Å; T127-Y291 HydrophobicContact CG2-CD1 3.72Å; T127-Y291 HydrophobicContact CG2-CE1 4.31Å; T127-L294 HydrophobicContact CG2-CD2 3.89Å; T127-I449 HydrophobicContact CG2-CD1 3.58Å; T127-I449 HydrophobicContact CG2-CG1 4.12Å
128	T	87.2	Confident	84.2	Confident	25 Å²	25	16 Å²	16	15%	0.153	9%	0.092	C	C	.	.	H	α-helix	trans	-85.4	-41.5	175.5	-51.5	0	0	0	0	111.6	E124 L125 L438 R447	E124-T128 WeakPolarHBondContact O-CB 3.3Å; E124-T128 PolarHBondContact O-N 2.9Å; E124-T128 PolarHBondContact O-OG1 2.85Å; L125-T128 PolarHBondContact O-N 3.09Å; T128-L438 HydrophobicContact CG2-CD2 4.18Å; T128-R447 HydrophobicContact CG2-CG 4.13Å
129	I	83.8	Confident	84.2	Confident	14 Å²	14	16.1 Å²	16.1	7%	0.072	9%	0.093	C	C	.	.			trans	-115.2	91.5	179.1	-55	170.6	0	0	0	107.2	L125 K131 Y138 E141 L438	L125-I129 HydrophobicContact CD1-CD1 3.99Å; L125-I129 PolarHBondContact O-N 2.63Å; I129-K131 HydrophobicContact CG2-CB 4.31Å; I129-K131 HydrophobicContact CG2-CG 4.44Å; I129-K131 PolarHBondContact O-N 2.71Å; I129-Y138 HydrophobicContact CB-CD1 3.89Å; I129-Y138 HydrophobicContact CB-CE1 4.01Å; I129-Y138 HydrophobicContact CD1-CD1 4.08Å; I129-Y138 HydrophobicContact CG2-CD1 4Å; I129-Y138 HydrophobicContact CG2-CE1 4.28Å; I129-Y138 WeakPolarHBondContact O-CE1 3.28Å; I129-E141 HydrophobicContact CD1-CB 4.05Å; I129-E141 HydrophobicContact CD1-CG 4.05Å; I129-E141 HydrophobicContact CG1-CG 4.49Å; I129-L438 HydrophobicContact CD1-CD2 4.35Å
130	S	71.9	Confident	84.1	Confident	76 Å²	76	18 Å²	18	53%	0.531	10%	0.103	S	C	.	.			trans	-79.5	11.2	-175.7	52.1	0	0	0	0	114.6	E285	S130-E285 WeakPolarHBondContact O-CG 3.34Å
131	K	72.1	Confident	84	Confident	116 Å²	116	20 Å²	20	50%	0.504	11%	0.111	S	C	.	.			trans	-74.8	135.7	179.9	-66.4	179.4	-179.7	169.7	0	111.6	I129 A137 E141	I129-K131 HydrophobicContact CG2-CB 4.31Å; I129-K131 HydrophobicContact CG2-CG 4.44Å; I129-K131 PolarHBondContact O-N 2.71Å; K131-A137 HydrophobicContact CB-CB 4.31Å; K131-E141 IonicContact NZ-OE2 3.98Å; K131-E141 PolarHBondContact NZ-OE2 3.38Å
132	S	65.9	Low	84	Confident	38 Å²	38	20.6 Å²	20.6	27%	0.266	11%	0.114	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.2	135.9	170.7	-164.9	0	0	0	0	112	E285	S132-E285 WeakPolarHBondContact CB-OE1 3.49Å; S132-E285 PolarHBondContact N-OE1 3.22Å
133	G	68.3	Low	84.1	Confident	4 Å²	4	24.2 Å²	24.2	4%	0.041	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	129.6	-5.4	-177.9	0	0	0	0	0	115.1	D135 Y136 F282	G133-D135 PolarHBondContact O-N 3.29Å; G133-Y136 PolarHBondContact O-N 3.44Å; G133-F282 WeakPolarHBondContact O-CE1 3.38Å
134	G	80.2	Confident	84.2	Confident	1 Å²	1	25.5 Å²	25.5	1%	0.01	14%	0.142	C	C	.	.	T	Hydrogen-bonded Turn	trans	50.3	-127.6	174.9	0	0	0	0	0	112.7	Y136 A137 Y138 F282	G134-Y136 PolarHBondContact O-N 3.26Å; G134-Y136 VanDerWaalsContact O-N 3.08Å; G134-A137 PolarHBondContact O-N 3.49Å; G134-Y138 WeakPolarHBondContact O-CD1 3.43Å; G134-Y138 VanDerWaalsContact O-CD2 3.31Å; G134-Y138 WeakPolarHBondContact O-CD2 3.28Å; G134-Y138 VanDerWaalsContact O-CG 3.22Å; G134-Y138 PolarHBondContact O-N 3.33Å; G134-F282 VanDerWaalsContact CA-CE1 3.42Å
135	D	82.6	Confident	84.2	Confident	4 Å²	4	27.4 Å²	27.4	2%	0.021	16%	0.155	C	C	.	.	H	α-helix	trans	-50.1	-39.2	-177.2	-59	-42.3	0	0	0	113.8	Y122 G133 Y138 I139 K151 N278	Y122-D135 WeakPolarHBondContact CE1-OD1 3.22Å; Y122-D135 PolarHBondContact OH-OD1 3.03Å; G133-D135 PolarHBondContact O-N 3.29Å; D135-Y138 PolarHBondContact O-N 2.92Å; D135-I139 WeakPolarHBondContact O-CB 3.45Å; D135-I139 WeakPolarHBondContact O-CG1 3.4Å; D135-I139 PolarHBondContact O-N 3.3Å; D135-K151 HydrophobicContact CB-CD 4.17Å; D135-K151 IonicContact OD2-NZ 3.87Å; D135-N278 PolarHBondContact OD2-ND2 3.4Å
136	Y	87	Confident	84.5	Confident	1 Å²	1	29.9 Å²	29.9	0%	0.004	17%	0.168	C	C	.	.	H	α-helix	trans	-66.5	-45.6	-179.2	167	-97	0	0	0	111.3	G133 G134 Y138 I139 L140 A148 L152 V372 E376 H378	G133-Y136 PolarHBondContact O-N 3.44Å; G134-Y136 PolarHBondContact O-N 3.26Å; G134-Y136 VanDerWaalsContact O-N 3.08Å; Y136-Y138 VanDerWaalsContact C-N 3.32Å; Y136-Y138 PolarHBondContact O-N 3.18Å; Y136-I139 PolarHBondContact O-N 3.25Å; Y136-L140 HydrophobicContact CE1-CD2 4.24Å; Y136-L140 VanDerWaalsContact O-CB 3.3Å; Y136-L140 WeakPolarHBondContact O-CB 3.39Å; Y136-L140 PolarHBondContact O-N 3.31Å; Y136-A148 HydrophobicContact CD2-CB 4.09Å; Y136-A148 VanDerWaalsContact CD2-O 3.3Å; Y136-A148 WeakPolarHBondContact CD2-O 3.43Å; Y136-A148 HydrophobicContact CE2-CB 3.7Å; Y136-A148 WeakPolarHBondContact CE2-O 3.17Å; Y136-L152 HydrophobicContact CD2-CB 3.89Å; Y136-L152 HydrophobicContact CD2-CD1 4.47Å; Y136-L152 HydrophobicContact CE2-CB 4.04Å; Y136-L152 HydrophobicContact CE2-CD2 4.1Å; Y136-V372 HydrophobicContact CD1-CG1 3.82Å; Y136-V372 HydrophobicContact CE1-CG1 3.8Å; Y136-E376 HydrophobicContact CE1-CG 4.01Å; Y136-E376 VanDerWaalsContact OH-CB 3.28Å; Y136-E376 WeakPolarHBondContact OH-CB 3.28Å; Y136-E376 WeakPolarHBondContact OH-CG 3.27Å; Y136-H378 AromaticContact CE2-ND1 3.74Å; Y136-H378 AromaticContact CZ-ND1 3.67Å; Y136-H378 PolarHBondContact OH-CE1 3.39Å; Y136-H378 VanDerWaalsContact OH-CE1 3.25Å; Y136-H378 PolarHBondContact OH-ND1 3.26Å
137	A	85.4	Confident	84.9	Confident	7 Å²	7	32.7 Å²	32.7	6%	0.058	18%	0.183	C	C	.	.	H	α-helix	trans	-64.9	-37.9	178.3	0	0	0	0	0	111.5	K131 G134 L140 E141	K131-A137 HydrophobicContact CB-CB 4.31Å; G134-A137 PolarHBondContact O-N 3.49Å; A137-L140 PolarHBondContact O-N 3.24Å; A137-E141 PolarHBondContact O-N 3.42Å
138	Y	88.6	Confident	85.2	Confident	4 Å²	4	32.5 Å²	32.5	2%	0.016	18%	0.181	C	C	.	.	H	α-helix	trans	-65.3	-45.9	177.6	-54.6	-27.5	0	0	0	112.3	Y122 L125 G126 I129 G134 D135 Y136 L140 E141 V142 N281	Y122-Y138 HydrophobicContact CD1-CE2 4.07Å; Y122-Y138 HydrophobicContact CE1-CD2 4.26Å; Y122-Y138 HydrophobicContact CE1-CE2 4.01Å; L125-Y138 HydrophobicContact CB-CE2 4.35Å; L125-Y138 HydrophobicContact CD1-CG 4.45Å; L125-Y138 HydrophobicContact CD2-CD1 4.34Å; L125-Y138 HydrophobicContact CD2-CD2 3.23Å; L125-Y138 HydrophobicContact CD2-CE2 3.81Å; L125-Y138 HydrophobicContact CD2-CG 3.54Å; L125-Y138 HydrophobicContact CG-CD1 3.94Å; L125-Y138 HydrophobicContact CG-CD2 3.65Å; L125-Y138 HydrophobicContact CG-CE1 4.22Å; L125-Y138 HydrophobicContact CG-CE2 3.92Å; L125-Y138 HydrophobicContact CG-CG 3.65Å; G126-Y138 WeakPolarHBondContact CA-OH 3.48Å; G126-Y138 PolarHBondContact N-OH 2.86Å; I129-Y138 HydrophobicContact CB-CD1 3.89Å; I129-Y138 HydrophobicContact CB-CE1 4.01Å; I129-Y138 HydrophobicContact CD1-CD1 4.08Å; I129-Y138 HydrophobicContact CG2-CD1 4Å; I129-Y138 HydrophobicContact CG2-CE1 4.28Å; I129-Y138 WeakPolarHBondContact O-CE1 3.28Å; G134-Y138 WeakPolarHBondContact O-CD1 3.43Å; G134-Y138 VanDerWaalsContact O-CD2 3.31Å; G134-Y138 WeakPolarHBondContact O-CD2 3.28Å; G134-Y138 VanDerWaalsContact O-CG 3.22Å; G134-Y138 PolarHBondContact O-N 3.33Å; D135-Y138 PolarHBondContact O-N 2.92Å; Y136-Y138 VanDerWaalsContact C-N 3.32Å; Y136-Y138 PolarHBondContact O-N 3.18Å; Y138-L140 VanDerWaalsContact C-N 3.31Å; Y138-L140 PolarHBondContact O-N 3.02Å; Y138-E141 PolarHBondContact O-N 3.48Å; Y138-V142 WeakPolarHBondContact O-CG2 3.47Å; Y138-V142 PolarHBondContact O-N 3.19Å; Y138-V142 VanDerWaalsContact O-N 3.13Å; Y138-N281 WeakPolarHBondContact OH-CB 3.4Å
139	I	91.3	Very high	85.5	Confident	3 Å²	3	31.5 Å²	31.5	2%	0.015	18%	0.175	C	C	.	.	H	α-helix	trans	-67.7	-35.8	178.4	-70.5	165.9	0	0	0	110.6	D135 Y136 V142 Y143 G144 L147 A148 K151	D135-I139 WeakPolarHBondContact O-CB 3.45Å; D135-I139 WeakPolarHBondContact O-CG1 3.4Å; D135-I139 PolarHBondContact O-N 3.3Å; Y136-I139 PolarHBondContact O-N 3.25Å; I139-V142 PolarHBondContact O-N 3.42Å; I139-Y143 HydrophobicContact CB-CD2 4.4Å; I139-Y143 HydrophobicContact CG1-CD2 4.41Å; I139-Y143 HydrophobicContact CG2-CD2 4Å; I139-Y143 WeakPolarHBondContact O-CA 3.31Å; I139-Y143 WeakPolarHBondContact O-CB 3.36Å; I139-Y143 PolarHBondContact O-N 2.94Å; I139-G144 PolarHBondContact O-N 2.92Å; I139-L147 HydrophobicContact CG2-CB 4Å; I139-A148 HydrophobicContact CG2-CB 4.41Å; I139-K151 HydrophobicContact CD1-CB 3.86Å; I139-K151 HydrophobicContact CD1-CD 4.35Å; I139-K151 HydrophobicContact CD1-CG 3.61Å
140	L	91	Very high	86	Confident	40 Å²	40	32 Å²	32	21%	0.209	18%	0.178	C	C	.	.	H	α-helix	trans	-61.2	-45.9	175.1	-176.6	62.8	0	0	0	112.3	Y136 A137 Y138 G144 A148 E376	Y136-L140 HydrophobicContact CE1-CD2 4.24Å; Y136-L140 VanDerWaalsContact O-CB 3.3Å; Y136-L140 WeakPolarHBondContact O-CB 3.39Å; Y136-L140 PolarHBondContact O-N 3.31Å; A137-L140 PolarHBondContact O-N 3.24Å; Y138-L140 VanDerWaalsContact C-N 3.31Å; Y138-L140 PolarHBondContact O-N 3.02Å; L140-G144 VanDerWaalsContact O-CA 3.28Å; L140-G144 WeakPolarHBondContact O-CA 3.38Å; L140-G144 PolarHBondContact O-N 2.99Å; L140-G144 VanDerWaalsContact O-N 3.09Å; L140-A148 HydrophobicContact CB-CB 3.7Å; L140-A148 HydrophobicContact CD1-CB 3.66Å; L140-A148 HydrophobicContact CG-CB 4.28Å; L140-E376 HydrophobicContact CD2-CG 4.25Å
141	E	89.5	Confident	87	Confident	75 Å²	75	28.5 Å²	28.5	35%	0.35	15%	0.153	S	C	.	.	H	α-helix	trans	-69.1	-33.7	-179	-169.7	65.1	-141.2	0	0	112.5	I129 K131 A137 Y138 K442	I129-E141 HydrophobicContact CD1-CB 4.05Å; I129-E141 HydrophobicContact CD1-CG 4.05Å; I129-E141 HydrophobicContact CG1-CG 4.49Å; K131-E141 IonicContact NZ-OE2 3.98Å; K131-E141 PolarHBondContact NZ-OE2 3.38Å; A137-E141 PolarHBondContact O-N 3.42Å; Y138-E141 PolarHBondContact O-N 3.48Å; E141-K442 IonicContact OE1-NZ 2.87Å
142	V	91.4	Very high	87.9	Confident	14 Å²	14	23 Å²	23	9%	0.085	13%	0.129	C	C	.	.	H	α-helix	trans	-89	-48.8	-176.3	176.7	0	0	0	0	112.8	Y138 I139 W437	Y138-V142 WeakPolarHBondContact O-CG2 3.47Å; Y138-V142 PolarHBondContact O-N 3.19Å; Y138-V142 VanDerWaalsContact O-N 3.13Å; I139-V142 PolarHBondContact O-N 3.42Å; V142-W437 HydrophobicContact CG1-CE3 3.66Å; V142-W437 HydrophobicContact CG1-CZ3 3.95Å
143	Y	92.9	Very high	89.2	Confident	78 Å²	78	23.5 Å²	23.5	31%	0.306	13%	0.125	S	C	.	.	H	α-helix	trans	-107.8	-13.1	-168.7	-64.2	-74.1	0	0	0	113.9	I139 L147 M430 G434	I139-Y143 HydrophobicContact CB-CD2 4.4Å; I139-Y143 HydrophobicContact CG1-CD2 4.41Å; I139-Y143 HydrophobicContact CG2-CD2 4Å; I139-Y143 WeakPolarHBondContact O-CA 3.31Å; I139-Y143 WeakPolarHBondContact O-CB 3.36Å; I139-Y143 PolarHBondContact O-N 2.94Å; Y143-L147 HydrophobicContact CD1-CD2 3.75Å; Y143-L147 HydrophobicContact CG-CD2 3.75Å; Y143-M430 WeakPolarHBondContact CE2-O 3.46Å; Y143-M430 PolarHBondContact OH-O 3.39Å; Y143-M430 VanDerWaalsContact OH-O 3.11Å; Y143-G434 WeakPolarHBondContact OH-CA 2.89Å; Y143-G434 PolarHBondContact OH-N 3.13Å; Y143-G434 VanDerWaalsContact OH-N 3.09Å
144	G	91.4	Very high	90.4	Very high	28 Å²	28	23.5 Å²	23.5	29%	0.289	12%	0.124	S	C	.	.			trans	87.1	-173.6	-179.9	0	0	0	0	0	114.6	I139 L140 L146 A148	I139-G144 PolarHBondContact O-N 2.92Å; L140-G144 VanDerWaalsContact O-CA 3.28Å; L140-G144 WeakPolarHBondContact O-CA 3.38Å; L140-G144 PolarHBondContact O-N 2.99Å; L140-G144 VanDerWaalsContact O-N 3.09Å; G144-L146 PolarHBondContact O-N 3.39Å; G144-A148 WeakPolarHBondContact O-CB 3.34Å; G144-A148 PolarHBondContact O-N 3.36Å
145	S	90.5	Very high	90.9	Very high	39 Å²	39	23.8 Å²	23.8	27%	0.273	13%	0.125	S	C	.	.	H	α-helix	trans	-64	-40.9	-165.6	166.9	0	0	0	0	114.4	A148 F149 H378 Y492	S145-A148 PolarHBondContact O-N 3.38Å; S145-F149 WeakPolarHBondContact O-CB 3.48Å; S145-F149 PolarHBondContact O-N 3.03Å; S145-H378 PolarHBondContact OG-CE1 3.27Å; S145-H378 PolarHBondContact OG-NE2 2.84Å; S145-Y492 VanDerWaalsContact CB-OH 3.32Å; S145-Y492 WeakPolarHBondContact CB-OH 3.28Å; S145-Y492 WeakPolarHBondContact OG-CE2 3.42Å; S145-Y492 PolarHBondContact OG-OH 3.19Å
146	L	92.8	Very high	91.3	Very high	54 Å²	54	24 Å²	24	28%	0.283	13%	0.126	S	C	.	.	H	α-helix	trans	-61.5	-50.7	-178	176.7	67.7	0	0	0	112	G144 A148 F149 L150 L489 Y492	G144-L146 PolarHBondContact O-N 3.39Å; L146-A148 VanDerWaalsContact C-N 3.33Å; L146-F149 PolarHBondContact O-N 3.19Å; L146-L150 WeakPolarHBondContact O-CG 3.36Å; L146-L150 PolarHBondContact O-N 2.89Å; L146-L489 HydrophobicContact CD1-CD2 3.98Å; L146-Y492 HydrophobicContact CB-CE1 3.94Å; L146-Y492 HydrophobicContact CD1-CD1 3.23Å; L146-Y492 HydrophobicContact CD1-CE1 3.47Å; L146-Y492 VanDerWaalsContact CD1-CE1 3.47Å; L146-Y492 HydrophobicContact CD1-CG 3.8Å; L146-Y492 HydrophobicContact CG-CD1 4.47Å; L146-Y492 HydrophobicContact CG-CE1 4.3Å; L146-Y492 PolarHBondContact N-OH 3.03Å
147	L	93.4	Very high	91.5	Very high	61 Å²	61	25.4 Å²	25.4	32%	0.319	13%	0.133	S	C	.	.	H	α-helix	trans	-71.3	-33.3	-177.3	-88.7	55.4	0	0	0	111.1	I139 Y143 L150 K151	I139-L147 HydrophobicContact CG2-CB 4Å; Y143-L147 HydrophobicContact CD1-CD2 3.75Å; Y143-L147 HydrophobicContact CG-CD2 3.75Å; L147-L150 PolarHBondContact O-N 2.63Å; L147-K151 PolarHBondContact O-N 3.01Å
148	A	92.2	Very high	91.8	Very high	0 Å²	0	25 Å²	25	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-63.2	-43.7	171.2	0	0	0	0	0	112	Y136 I139 L140 G144 S145 L146 K151 L152	Y136-A148 HydrophobicContact CD2-CB 4.09Å; Y136-A148 VanDerWaalsContact CD2-O 3.3Å; Y136-A148 WeakPolarHBondContact CD2-O 3.43Å; Y136-A148 HydrophobicContact CE2-CB 3.7Å; Y136-A148 WeakPolarHBondContact CE2-O 3.17Å; I139-A148 HydrophobicContact CG2-CB 4.41Å; L140-A148 HydrophobicContact CB-CB 3.7Å; L140-A148 HydrophobicContact CD1-CB 3.66Å; L140-A148 HydrophobicContact CG-CB 4.28Å; G144-A148 WeakPolarHBondContact O-CB 3.34Å; G144-A148 PolarHBondContact O-N 3.36Å; S145-A148 PolarHBondContact O-N 3.38Å; L146-A148 VanDerWaalsContact C-N 3.33Å; A148-K151 PolarHBondContact O-N 3.25Å; A148-L152 WeakPolarHBondContact O-CB 3.42Å; A148-L152 PolarHBondContact O-N 3.24Å
149	F	93	Very high	91.9	Very high	5 Å²	5	25.1 Å²	25.1	2%	0.022	13%	0.131	C	C	.	.	H	α-helix	trans	-61.3	-46.4	174.3	177.6	-86.4	0	0	0	111.4	S145 L146 K151 L152 W153 H378 G488 V491 Y492 V496	S145-F149 WeakPolarHBondContact O-CB 3.48Å; S145-F149 PolarHBondContact O-N 3.03Å; L146-F149 PolarHBondContact O-N 3.19Å; F149-K151 VanDerWaalsContact C-N 3.32Å; F149-K151 PolarHBondContact O-N 3.25Å; F149-L152 CarbonylContact O-C 3.41Å; F149-L152 WeakPolarHBondContact O-CB 3.43Å; F149-L152 PolarHBondContact O-N 2.57Å; F149-L152 VanDerWaalsContact O-N 3.15Å; F149-W153 HydrophobicContact CE1-CB 4.28Å; F149-W153 HydrophobicContact CE1-CD2 4.23Å; F149-W153 AromaticContact CE1-CE3 3.99Å; F149-W153 HydrophobicContact CE1-CE3 3.99Å; F149-W153 HydrophobicContact CE1-CG 4.38Å; F149-W153 HydrophobicContact CZ-CD2 4.33Å; F149-W153 AromaticContact CZ-CE3 3.64Å; F149-W153 HydrophobicContact CZ-CE3 3.64Å; F149-W153 HydrophobicContact CZ-CZ3 4.09Å; F149-W153 WeakPolarHBondContact O-CB 3.48Å; F149-W153 PolarHBondContact O-N 3.49Å; F149-H378 HydrophobicContact CD2-CB 3.96Å; F149-H378 WeakPolarHBondContact CE2-O 3.49Å; F149-G488 VanDerWaalsContact CE1-O 3.27Å; F149-G488 WeakPolarHBondContact CE1-O 3.19Å; F149-V491 HydrophobicContact CZ-CB 4.4Å; F149-V491 HydrophobicContact CZ-CG1 3.96Å; F149-Y492 HydrophobicContact CB-CD2 3.48Å; F149-Y492 VanDerWaalsContact CB-CD2 3.48Å; F149-Y492 HydrophobicContact CB-CE2 3.8Å; F149-Y492 HydrophobicContact CB-CG 4.43Å; F149-Y492 AromaticContact CD1-CD2 3.8Å; F149-Y492 HydrophobicContact CD1-CD2 3.8Å; F149-Y492 HydrophobicContact CD1-CG 4.1Å; F149-Y492 AromaticContact CD2-CD2 3.79Å; F149-Y492 HydrophobicContact CD2-CD2 3.79Å; F149-Y492 AromaticContact CG-CD2 3.39Å; F149-Y492 HydrophobicContact CG-CD2 3.39Å; F149-Y492 HydrophobicContact CG-CE2 4.19Å; F149-Y492 HydrophobicContact CG-CG 4.17Å; F149-V496 HydrophobicContact CD2-CG2 4.36Å
150	L	94.1	Very high	91.9	Very high	25 Å²	25	25.5 Å²	25.5	13%	0.131	13%	0.133	C	C	.	.	H	α-helix	trans	-61.8	-39.9	177.7	-69.5	177.6	0	0	0	111.8	L146 L147 W153 I154 I485 L489	L146-L150 WeakPolarHBondContact O-CG 3.36Å; L146-L150 PolarHBondContact O-N 2.89Å; L147-L150 PolarHBondContact O-N 2.63Å; L150-W153 WeakPolarHBondContact O-CB 3.33Å; L150-W153 PolarHBondContact O-N 3.34Å; L150-I154 WeakPolarHBondContact O-CD1 3.44Å; L150-I154 VanDerWaalsContact O-CG1 3.24Å; L150-I154 WeakPolarHBondContact O-CG1 3.3Å; L150-I154 PolarHBondContact O-N 3.16Å; L150-I485 HydrophobicContact CD2-CG2 4.26Å; L150-L489 HydrophobicContact CD1-CD2 4.12Å; L150-L489 HydrophobicContact CD2-CD2 4.3Å; L150-L489 HydrophobicContact CD2-CG 4.44Å
151	K	92.4	Very high	92	Very high	1 Å²	1	23.6 Å²	23.6	0%	0.004	12%	0.123	C	C	.	.	H	α-helix	trans	-62.1	-44.3	173.5	-174	-96	163.2	-176	0	111.8	D135 I139 L147 A148 F149 W153 I154 E155	D135-K151 HydrophobicContact CB-CD 4.17Å; D135-K151 IonicContact OD2-NZ 3.87Å; I139-K151 HydrophobicContact CD1-CB 3.86Å; I139-K151 HydrophobicContact CD1-CD 4.35Å; I139-K151 HydrophobicContact CD1-CG 3.61Å; L147-K151 PolarHBondContact O-N 3.01Å; A148-K151 PolarHBondContact O-N 3.25Å; F149-K151 VanDerWaalsContact C-N 3.32Å; F149-K151 PolarHBondContact O-N 3.25Å; K151-W153 VanDerWaalsContact C-N 3.31Å; K151-W153 PolarHBondContact O-N 2.9Å; K151-I154 PolarHBondContact O-N 2.88Å; K151-E155 WeakPolarHBondContact CE-OE2 3.49Å; K151-E155 IonicContact NZ-OE2 2.77Å; K151-E155 PolarHBondContact NZ-OE2 2.69Å; K151-E155 WeakPolarHBondContact O-CB 3.35Å; K151-E155 PolarHBondContact O-N 2.95Å
152	L	91.8	Very high	92.1	Very high	1 Å²	1	20 Å²	20	1%	0.005	11%	0.106	C	C	.	.	H	α-helix	trans	-61	-43.2	176.2	-175.2	63.4	0	0	0	110.9	Y136 A148 F149 E155 L156 L369 H378 L379	Y136-L152 HydrophobicContact CD2-CB 3.89Å; Y136-L152 HydrophobicContact CD2-CD1 4.47Å; Y136-L152 HydrophobicContact CE2-CB 4.04Å; Y136-L152 HydrophobicContact CE2-CD2 4.1Å; A148-L152 WeakPolarHBondContact O-CB 3.42Å; A148-L152 PolarHBondContact O-N 3.24Å; F149-L152 CarbonylContact O-C 3.41Å; F149-L152 WeakPolarHBondContact O-CB 3.43Å; F149-L152 PolarHBondContact O-N 2.57Å; F149-L152 VanDerWaalsContact O-N 3.15Å; L152-E155 WeakPolarHBondContact O-CB 3.36Å; L152-E155 PolarHBondContact O-N 3.38Å; L152-L156 HydrophobicContact CD1-CD1 4.3Å; L152-L156 HydrophobicContact CD1-CG 4.3Å; L152-L156 HydrophobicContact CG-CD1 4.12Å; L152-L156 HydrophobicContact CG-CG 4.45Å; L152-L156 WeakPolarHBondContact O-CB 3.45Å; L152-L156 WeakPolarHBondContact O-CG 3.08Å; L152-L156 PolarHBondContact O-N 3.47Å; L152-L369 HydrophobicContact CD1-CD1 3.78Å; L152-L369 HydrophobicContact CD1-CD2 3.87Å; L152-L369 HydrophobicContact CD1-CG 3.57Å; L152-H378 HydrophobicContact CD2-CB 4.17Å; L152-L379 HydrophobicContact CD2-CD1 3.86Å; L152-L379 HydrophobicContact CD2-CD2 4.22Å; L152-L379 HydrophobicContact CD2-CG 3.77Å; L152-L379 HydrophobicContact CG-CD1 4.42Å
153	W	93.7	Very high	92.1	Very high	49 Å²	49	20.6 Å²	20.6	19%	0.186	11%	0.11	C	C	.	.	H	α-helix	trans	-59.6	-46.9	177.2	-165.9	-104.3	0	0	0	112.4	F149 L150 K151 L156 L157 I484 V491	F149-W153 HydrophobicContact CE1-CB 4.28Å; F149-W153 HydrophobicContact CE1-CD2 4.23Å; F149-W153 AromaticContact CE1-CE3 3.99Å; F149-W153 HydrophobicContact CE1-CE3 3.99Å; F149-W153 HydrophobicContact CE1-CG 4.38Å; F149-W153 HydrophobicContact CZ-CD2 4.33Å; F149-W153 AromaticContact CZ-CE3 3.64Å; F149-W153 HydrophobicContact CZ-CE3 3.64Å; F149-W153 HydrophobicContact CZ-CZ3 4.09Å; F149-W153 WeakPolarHBondContact O-CB 3.48Å; F149-W153 PolarHBondContact O-N 3.49Å; L150-W153 WeakPolarHBondContact O-CB 3.33Å; L150-W153 PolarHBondContact O-N 3.34Å; K151-W153 VanDerWaalsContact C-N 3.31Å; K151-W153 PolarHBondContact O-N 2.9Å; W153-L156 PolarHBondContact O-N 3.17Å; W153-L157 HydrophobicContact CD2-CD1 3.95Å; W153-L157 HydrophobicContact CG-CD1 4.31Å; W153-L157 HydrophobicContact CH2-CD1 4.34Å; W153-L157 HydrophobicContact CZ2-CD1 3.59Å; W153-L157 WeakPolarHBondContact O-CB 3.43Å; W153-L157 PolarHBondContact O-N 3.07Å; W153-I484 PolarHBondContact NE1-O 2.54Å; W153-I484 VanDerWaalsContact NE1-O 3.11Å; W153-V491 HydrophobicContact CH2-CB 4.23Å; W153-V491 HydrophobicContact CH2-CG1 3.87Å; W153-V491 HydrophobicContact CH2-CG2 3.99Å; W153-V491 HydrophobicContact CZ2-CG2 4.15Å; W153-V491 HydrophobicContact CZ3-CG1 3.86Å
154	I	93.3	Very high	92	Very high	4 Å²	4	16.9 Å²	16.9	2%	0.021	10%	0.096	C	C	.	.	H	α-helix	trans	-61	-46	174.2	-68	162.6	0	0	0	110.7	L150 K151 L156 I158 I159 F423 I485	L150-I154 WeakPolarHBondContact O-CD1 3.44Å; L150-I154 VanDerWaalsContact O-CG1 3.24Å; L150-I154 WeakPolarHBondContact O-CG1 3.3Å; L150-I154 PolarHBondContact O-N 3.16Å; K151-I154 PolarHBondContact O-N 2.88Å; I154-L156 VanDerWaalsContact C-N 3.29Å; I154-L156 PolarHBondContact O-N 2.93Å; I154-I158 HydrophobicContact CG2-CB 4.41Å; I154-I158 HydrophobicContact CG2-CD1 4.47Å; I154-I158 WeakPolarHBondContact O-CA 3.11Å; I154-I158 VanDerWaalsContact O-CB 3.28Å; I154-I158 WeakPolarHBondContact O-CB 3.49Å; I154-I158 PolarHBondContact O-N 3.39Å; I154-I159 HydrophobicContact CG2-CD1 3.8Å; I154-I159 HydrophobicContact CG2-CG1 3.96Å; I154-I159 PolarHBondContact O-N 3.38Å; I154-I159 VanDerWaalsContact O-N 3.07Å; I154-F423 HydrophobicContact CG2-CB 3.83Å; I154-F423 HydrophobicContact CG2-CD1 4.44Å; I154-F423 HydrophobicContact CG2-CG 4.34Å; I154-I485 HydrophobicContact CD1-CD1 3.51Å; I154-I485 HydrophobicContact CD1-CG1 3.73Å; I154-I485 HydrophobicContact CG1-CD1 3.84Å; I154-I485 HydrophobicContact CG1-CG1 3.54Å
155	E	90.4	Very high	92.2	Very high	7 Å²	7	15.7 Å²	15.7	3%	0.033	8%	0.083	C	C	.	.	I	π-helix	trans	-61	-41.9	-178.2	-170.9	76	-158	0	0	111.5	K151 L152 R160 L369	K151-E155 WeakPolarHBondContact CE-OE2 3.49Å; K151-E155 IonicContact NZ-OE2 2.77Å; K151-E155 PolarHBondContact NZ-OE2 2.69Å; K151-E155 WeakPolarHBondContact O-CB 3.35Å; K151-E155 PolarHBondContact O-N 2.95Å; L152-E155 WeakPolarHBondContact O-CB 3.36Å; L152-E155 PolarHBondContact O-N 3.38Å; E155-R160 HydrophobicContact CG-CG 4.08Å; E155-R160 WeakPolarHBondContact O-CB 3.24Å; E155-R160 VanDerWaalsContact O-CG 3.26Å; E155-R160 WeakPolarHBondContact O-CG 3.33Å; E155-R160 PolarHBondContact O-N 2.95Å; E155-R160 IonicContact OE1-CZ 2.81Å; E155-R160 IonicContact OE1-NE 3.99Å; E155-R160 PolarHBondContact OE1-NE 3.18Å; E155-R160 IonicContact OE1-NH2 3.5Å; E155-R160 PolarHBondContact OE1-NH2 3.14Å; E155-L369 HydrophobicContact CB-CD2 3.98Å; E155-L369 HydrophobicContact CG-CD2 3.24Å
156	L	90.4	Very high	92.2	Very high	7 Å²	7	13.8 Å²	13.8	4%	0.037	7%	0.07	C	C	.	.	I	π-helix	trans	-77.2	-37.3	-176.2	-70	-175.7	0	0	0	114.5	L152 W153 I154 P161 L369 F370 L379	L152-L156 HydrophobicContact CD1-CD1 4.3Å; L152-L156 HydrophobicContact CD1-CG 4.3Å; L152-L156 HydrophobicContact CG-CD1 4.12Å; L152-L156 HydrophobicContact CG-CG 4.45Å; L152-L156 WeakPolarHBondContact O-CB 3.45Å; L152-L156 WeakPolarHBondContact O-CG 3.08Å; L152-L156 PolarHBondContact O-N 3.47Å; W153-L156 PolarHBondContact O-N 3.17Å; I154-L156 VanDerWaalsContact C-N 3.29Å; I154-L156 PolarHBondContact O-N 2.93Å; L156-P161 WeakPolarHBondContact O-CD 3.32Å; L156-P161 WeakPolarHBondContact O-CG 3.48Å; L156-L369 HydrophobicContact CD2-CD2 3.91Å; L156-F370 HydrophobicContact CD1-CD1 4.23Å; L156-F370 HydrophobicContact CD1-CE1 3.81Å; L156-F370 HydrophobicContact CD1-CZ 4.38Å; L156-F370 HydrophobicContact CD2-CD1 4.12Å; L156-F370 HydrophobicContact CD2-CD2 4.25Å; L156-F370 HydrophobicContact CD2-CE1 3.51Å; L156-F370 HydrophobicContact CD2-CE2 3.63Å; L156-F370 HydrophobicContact CD2-CG 4.46Å; L156-F370 HydrophobicContact CD2-CZ 3.23Å; L156-F370 HydrophobicContact CG-CE1 4.24Å; L156-F370 HydrophobicContact CG-CZ 4.32Å; L156-L379 HydrophobicContact CD1-CD1 3.88Å; L156-L379 HydrophobicContact CD1-CD2 3.84Å; L156-L379 HydrophobicContact CD1-CG 4.49Å
157	L	92.1	Very high	92.1	Very high	31 Å²	31	11.7 Å²	11.7	16%	0.162	6%	0.059	C	C	.	.	I	π-helix	trans	-96.5	-29.8	-175.7	-63.4	-175.6	0	0	0	113.1	W153 F399 M403 Y407 I484	W153-L157 HydrophobicContact CD2-CD1 3.95Å; W153-L157 HydrophobicContact CG-CD1 4.31Å; W153-L157 HydrophobicContact CH2-CD1 4.34Å; W153-L157 HydrophobicContact CZ2-CD1 3.59Å; W153-L157 WeakPolarHBondContact O-CB 3.43Å; W153-L157 PolarHBondContact O-N 3.07Å; L157-F399 HydrophobicContact CD2-CZ 4.22Å; L157-M403 HydrophobicContact CD2-CE 4.26Å; L157-M403 HydrophobicContact CD2-CG 4.36Å; L157-M403 HydrophobicContact CD2-SD 3.79Å; L157-Y407 WeakPolarHBondContact O-CE2 3.32Å; L157-Y407 PolarHBondContact O-OH 2.8Å; L157-I484 HydrophobicContact CB-CG2 4.24Å; L157-I484 HydrophobicContact CD1-CG2 3.96Å
158	I	91.9	Very high	92.1	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	4%	0.044	C	C	.	.	I	π-helix	trans	-109.9	-69	-173.6	-59.5	174.4	0	0	0	110.4	I154 P161 S162 F419 F423 I484	I154-I158 HydrophobicContact CG2-CB 4.41Å; I154-I158 HydrophobicContact CG2-CD1 4.47Å; I154-I158 WeakPolarHBondContact O-CA 3.11Å; I154-I158 VanDerWaalsContact O-CB 3.28Å; I154-I158 WeakPolarHBondContact O-CB 3.49Å; I154-I158 PolarHBondContact O-N 3.39Å; I158-P161 WeakPolarHBondContact O-CD 3.33Å; I158-S162 WeakPolarHBondContact O-CB 2.89Å; I158-S162 PolarHBondContact O-N 3.11Å; I158-S162 VanDerWaalsContact O-N 3.16Å; I158-S162 PolarHBondContact O-OG 3.43Å; I158-F419 HydrophobicContact CB-CE1 4.04Å; I158-F419 HydrophobicContact CD1-CE1 4.17Å; I158-F419 HydrophobicContact CD1-CZ 3.9Å; I158-F419 HydrophobicContact CG1-CE1 3.81Å; I158-F419 HydrophobicContact CG1-CZ 3.99Å; I158-F419 HydrophobicContact CG2-CD1 3.78Å; I158-F419 HydrophobicContact CG2-CE1 3.32Å; I158-F419 HydrophobicContact CG2-CZ 4.09Å; I158-F423 HydrophobicContact CD1-CD1 4.37Å; I158-F423 HydrophobicContact CD1-CD2 3.88Å; I158-F423 HydrophobicContact CD1-CE2 4.13Å; I158-F423 HydrophobicContact CD1-CG 4.05Å; I158-F423 HydrophobicContact CG2-CB 4.1Å; I158-F423 HydrophobicContact CG2-CD2 3.78Å; I158-F423 HydrophobicContact CG2-CG 4.17Å; I158-I484 HydrophobicContact CD1-CB 4.27Å; I158-I484 HydrophobicContact CD1-CG2 4.03Å; I158-I484 HydrophobicContact CG1-CD1 4.49Å; I158-I484 HydrophobicContact CG1-CG2 4.21Å
159	I	90.7	Very high	92.2	Very high	6 Å²	6	10.7 Å²	10.7	3%	0.031	5%	0.051	C	C	.	.	I	π-helix	trans	-64.2	-53	-164.1	-60.6	176.2	0	0	0	112	I154 S162 S163 F420	I154-I159 HydrophobicContact CG2-CD1 3.8Å; I154-I159 HydrophobicContact CG2-CG1 3.96Å; I154-I159 PolarHBondContact O-N 3.38Å; I154-I159 VanDerWaalsContact O-N 3.07Å; I159-S162 PolarHBondContact O-OG 2.77Å; I159-S163 VanDerWaalsContact O-CB 3.23Å; I159-S163 WeakPolarHBondContact O-CB 3.33Å; I159-S163 PolarHBondContact O-N 3.41Å; I159-F420 HydrophobicContact CB-CD2 4.48Å; I159-F420 HydrophobicContact CB-CE2 4.34Å; I159-F420 HydrophobicContact CG2-CD2 4.1Å; I159-F420 HydrophobicContact CG2-CE2 3.49Å; I159-F420 VanDerWaalsContact CG2-CE2 3.49Å; I159-F420 HydrophobicContact CG2-CZ 4.37Å; I159-F420 WeakPolarHBondContact O-CD2 3.11Å
160	R	89.9	Confident	92.1	Very high	10 Å²	10	10.7 Å²	10.7	4%	0.038	5%	0.052	C	C	.	.	H	α-helix	trans	-67.8	-50.1	-176.6	-63.4	-70	176.4	155.2	-5.1	113.1	E155 Q164 Y279 T365 S366	E155-R160 HydrophobicContact CG-CG 4.08Å; E155-R160 WeakPolarHBondContact O-CB 3.24Å; E155-R160 VanDerWaalsContact O-CG 3.26Å; E155-R160 WeakPolarHBondContact O-CG 3.33Å; E155-R160 PolarHBondContact O-N 2.95Å; E155-R160 IonicContact OE1-CZ 2.81Å; E155-R160 IonicContact OE1-NE 3.99Å; E155-R160 PolarHBondContact OE1-NE 3.18Å; E155-R160 IonicContact OE1-NH2 3.5Å; E155-R160 PolarHBondContact OE1-NH2 3.14Å; R160-Q164 VanDerWaalsContact O-CG 3.31Å; R160-Q164 WeakPolarHBondContact O-CG 3.5Å; R160-Q164 PolarHBondContact O-N 2.82Å; R160-Q164 VanDerWaalsContact O-N 3.07Å; R160-Y279 PolarHBondContact NH1-OH 3.38Å; R160-Y279 PolarHBondContact NH2-OH 3.5Å; R160-T365 PolarHBondContact NH1-OG1 3.33Å; R160-S366 WeakPolarHBondContact CD-OG 3.36Å
161	P	93.1	Very high	91.9	Very high	1 Å²	1	10.9 Å²	10.9	1%	0.006	5%	0.052	C	C	.	.	H	α-helix	trans	-66.6	-43.8	-176.7	-22.5	35.9	0	0	0	112.8	L156 I158 S163 Q164 Y165 M403 T404 Y407	L156-P161 WeakPolarHBondContact O-CD 3.32Å; L156-P161 WeakPolarHBondContact O-CG 3.48Å; I158-P161 WeakPolarHBondContact O-CD 3.33Å; P161-S163 PolarHBondContact O-N 3.23Å; P161-Q164 PolarHBondContact O-N 2.92Å; P161-Y165 WeakPolarHBondContact O-CB 3.21Å; P161-Y165 PolarHBondContact O-N 3.21Å; P161-M403 HydrophobicContact CB-CB 3.97Å; P161-M403 HydrophobicContact CG-CB 3.65Å; P161-T404 WeakPolarHBondContact CA-OG1 3.38Å; P161-Y407 HydrophobicContact CB-CD2 3.78Å; P161-Y407 HydrophobicContact CB-CE2 3.72Å
162	S	92.6	Very high	92	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-60.6	-46.4	177.5	59.3	0	0	0	0	112.2	I158 I159 Q164 Y165 I166 F420	I158-S162 WeakPolarHBondContact O-CB 2.89Å; I158-S162 PolarHBondContact O-N 3.11Å; I158-S162 VanDerWaalsContact O-N 3.16Å; I158-S162 PolarHBondContact O-OG 3.43Å; I159-S162 PolarHBondContact O-OG 2.77Å; S162-Q164 PolarHBondContact O-N 3.31Å; S162-Y165 PolarHBondContact O-N 2.67Å; S162-I166 WeakPolarHBondContact O-CD1 3.22Å; S162-I166 VanDerWaalsContact O-CG1 3.24Å; S162-I166 WeakPolarHBondContact O-CG1 3.37Å; S162-I166 PolarHBondContact O-N 3.48Å; S162-F420 WeakPolarHBondContact OG-CD2 3.3Å
163	S	90.6	Very high	92	Very high	25 Å²	25	11.3 Å²	11.3	18%	0.175	5%	0.054	C	C	.	.	H	α-helix	trans	-59.5	-46.4	177.3	177.3	0	0	0	0	111.6	I159 P161 Y165 I166 V167	I159-S163 VanDerWaalsContact O-CB 3.23Å; I159-S163 WeakPolarHBondContact O-CB 3.33Å; I159-S163 PolarHBondContact O-N 3.41Å; P161-S163 PolarHBondContact O-N 3.23Å; S163-Y165 VanDerWaalsContact C-N 3.34Å; S163-Y165 PolarHBondContact O-N 2.96Å; S163-I166 PolarHBondContact O-N 3.44Å; S163-V167 WeakPolarHBondContact O-CG2 3.37Å; S163-V167 PolarHBondContact O-N 3.36Å; S163-V167 VanDerWaalsContact O-N 3.14Å
164	Q	92.1	Very high	91.8	Very high	1 Å²	1	9 Å²	9	1%	0.005	5%	0.046	C	C	.	.	H	α-helix	trans	-60.7	-43.2	176.9	-72.9	171.4	11.7	0	0	112	R160 P161 S162 V167 A168 S362 S366 T404	R160-Q164 VanDerWaalsContact O-CG 3.31Å; R160-Q164 WeakPolarHBondContact O-CG 3.5Å; R160-Q164 PolarHBondContact O-N 2.82Å; R160-Q164 VanDerWaalsContact O-N 3.07Å; P161-Q164 PolarHBondContact O-N 2.92Å; S162-Q164 PolarHBondContact O-N 3.31Å; Q164-V167 PolarHBondContact O-N 3.01Å; Q164-A168 WeakPolarHBondContact O-CB 3.37Å; Q164-A168 PolarHBondContact O-N 3.46Å; Q164-S362 VanDerWaalsContact CG-OG 3.25Å; Q164-S362 WeakPolarHBondContact CG-OG 3.34Å; Q164-S362 PolarHBondContact NE2-OG 2.93Å; Q164-S366 PolarHBondContact NE2-OG 3.37Å; Q164-T404 HydrophobicContact CB-CG2 3.66Å; Q164-T404 PolarHBondContact OE1-OG1 3.24Å
165	Y	94.4	Very high	91.7	Very high	2 Å²	2	13.1 Å²	13.1	1%	0.008	7%	0.067	C	C	.	.	H	α-helix	trans	-65.3	-46.3	178.9	175.9	-104.4	0	0	0	112.2	P161 S162 S163 V167 A168 Y169 Y407 A408 S410	P161-Y165 WeakPolarHBondContact O-CB 3.21Å; P161-Y165 PolarHBondContact O-N 3.21Å; S162-Y165 PolarHBondContact O-N 2.67Å; S163-Y165 VanDerWaalsContact C-N 3.34Å; S163-Y165 PolarHBondContact O-N 2.96Å; Y165-V167 VanDerWaalsContact C-N 3.3Å; Y165-V167 PolarHBondContact O-N 3.33Å; Y165-A168 PolarHBondContact O-N 3.48Å; Y165-Y169 WeakPolarHBondContact O-CB 3.27Å; Y165-Y169 PolarHBondContact O-N 2.93Å; Y165-Y407 WeakPolarHBondContact CE1-O 3.16Å; Y165-A408 HydrophobicContact CD2-CB 4.46Å; Y165-A408 HydrophobicContact CE2-CB 3.79Å; Y165-S410 WeakPolarHBondContact CE1-OG 3.45Å
166	I	91.5	Very high	91.7	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-54	-50.3	176.4	-68.8	157.9	0	0	0	109.5	S162 S163 A168 Y169 V170 F272 I413 V416 I417 F420	S162-I166 WeakPolarHBondContact O-CD1 3.22Å; S162-I166 VanDerWaalsContact O-CG1 3.24Å; S162-I166 WeakPolarHBondContact O-CG1 3.37Å; S162-I166 PolarHBondContact O-N 3.48Å; S163-I166 PolarHBondContact O-N 3.44Å; I166-A168 PolarHBondContact O-N 3.4Å; I166-Y169 PolarHBondContact O-N 3.42Å; I166-V170 WeakPolarHBondContact O-CG2 3.28Å; I166-V170 PolarHBondContact O-N 3.42Å; I166-F272 HydrophobicContact CB-CZ 4.24Å; I166-F272 HydrophobicContact CD1-CE2 3.94Å; I166-F272 HydrophobicContact CD1-CZ 4.19Å; I166-F272 HydrophobicContact CG2-CE1 3.99Å; I166-F272 HydrophobicContact CG2-CE2 4.37Å; I166-F272 HydrophobicContact CG2-CZ 3.55Å; I166-I413 HydrophobicContact CG1-CG1 4.23Å; I166-I413 HydrophobicContact CG2-CD1 4.01Å; I166-I413 HydrophobicContact CG2-CG1 4.18Å; I166-V416 HydrophobicContact CD1-CB 4.47Å; I166-V416 HydrophobicContact CD1-CG1 3.88Å; I166-V416 HydrophobicContact CG1-CB 4.26Å; I166-V416 HydrophobicContact CG1-CG1 3.79Å; I166-I417 HydrophobicContact CD1-CB 4.39Å; I166-I417 HydrophobicContact CD1-CG1 3.62Å; I166-I417 HydrophobicContact CG1-CG1 4.03Å; I166-I417 HydrophobicContact CG2-CD1 4.24Å; I166-I417 HydrophobicContact CG2-CG1 4.03Å; I166-F420 HydrophobicContact CD1-CB 4.42Å
167	V	90.9	Very high	91.6	Very high	10 Å²	10	14.4 Å²	14.4	6%	0.061	7%	0.073	C	C	.	.	H	α-helix	trans	-66.3	-39.6	-179.1	-179.1	0	0	0	0	112.4	S85 S163 Q164 Y165 V170 F171 C355 V359	S85-V167 WeakPolarHBondContact OG-CG1 3.41Å; S85-V167 WeakPolarHBondContact OG-CG2 3.39Å; S163-V167 WeakPolarHBondContact O-CG2 3.37Å; S163-V167 PolarHBondContact O-N 3.36Å; S163-V167 VanDerWaalsContact O-N 3.14Å; Q164-V167 PolarHBondContact O-N 3.01Å; Y165-V167 VanDerWaalsContact C-N 3.3Å; Y165-V167 PolarHBondContact O-N 3.33Å; V167-V170 PolarHBondContact O-N 3.19Å; V167-F171 PolarHBondContact O-N 3.44Å; V167-C355 HydrophobicContact CG1-CB 3.89Å; V167-C355 WeakPolarHBondContact CG1-O 3.26Å; V167-V359 HydrophobicContact CB-CG2 3.79Å; V167-V359 HydrophobicContact CG1-CG2 3.59Å
168	A	93.5	Very high	91.4	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-67.2	-36.4	177.6	0	0	0	0	0	112.6	Q164 Y165 I166 F171 A172 A194 I198 V359	Q164-A168 WeakPolarHBondContact O-CB 3.37Å; Q164-A168 PolarHBondContact O-N 3.46Å; Y165-A168 PolarHBondContact O-N 3.48Å; I166-A168 PolarHBondContact O-N 3.4Å; A168-F171 WeakPolarHBondContact O-CB 3.07Å; A168-F171 PolarHBondContact O-N 3.04Å; A168-A172 PolarHBondContact O-N 3.01Å; A168-A172 VanDerWaalsContact O-N 3.09Å; A168-A194 HydrophobicContact CB-CB 4.13Å; A168-A194 WeakPolarHBondContact O-CB 3.38Å; A168-I198 HydrophobicContact CB-CD1 3.68Å; A168-I198 HydrophobicContact CB-CG1 3.61Å; A168-V359 HydrophobicContact CB-CG2 4.2Å
169	Y	93.1	Very high	91.3	Very high	39 Å²	39	21.8 Å²	21.8	15%	0.153	12%	0.115	C	C	.	.	H	α-helix	trans	-63.9	-43.7	173.9	-172.7	-86.1	0	0	0	111	Y165 I166 F171 A172 T173 A190 K191 I413	Y165-Y169 WeakPolarHBondContact O-CB 3.27Å; Y165-Y169 PolarHBondContact O-N 2.93Å; I166-Y169 PolarHBondContact O-N 3.42Å; Y169-F171 VanDerWaalsContact C-N 3.34Å; Y169-F171 PolarHBondContact O-N 3.08Å; Y169-A172 WeakPolarHBondContact O-CB 3.5Å; Y169-A172 PolarHBondContact O-N 3.03Å; Y169-A172 VanDerWaalsContact O-N 3.07Å; Y169-T173 WeakPolarHBondContact CE1-OG1 3.49Å; Y169-T173 PolarHBondContact O-N 3.45Å; Y169-T173 PolarHBondContact O-OG1 3.25Å; Y169-A190 HydrophobicContact CD2-CB 4.47Å; Y169-A190 HydrophobicContact CE2-CB 3.87Å; Y169-K191 HydrophobicContact CD2-CG 4.33Å; Y169-K191 HydrophobicContact CE2-CG 4Å; Y169-I413 HydrophobicContact CD1-CB 4.48Å; Y169-I413 HydrophobicContact CD1-CD1 3.48Å; Y169-I413 VanDerWaalsContact CD1-CD1 3.48Å; Y169-I413 HydrophobicContact CE1-CD1 4.26Å; Y169-I413 HydrophobicContact CG-CD1 4Å
170	V	90.4	Very high	91.2	Very high	5 Å²	5	24.6 Å²	24.6	3%	0.03	13%	0.127	C	C	.	.	H	α-helix	trans	-62.9	-42.8	177.5	174.1	0	0	0	0	110.9	V89 I166 V167 A172 T173 Y174 I413	V89-V170 HydrophobicContact CB-CG2 4.38Å; V89-V170 HydrophobicContact CG1-CG2 4.3Å; V89-V170 HydrophobicContact CG2-CB 3.89Å; V89-V170 HydrophobicContact CG2-CG1 3.31Å; V89-V170 HydrophobicContact CG2-CG2 3.23Å; I166-V170 WeakPolarHBondContact O-CG2 3.28Å; I166-V170 PolarHBondContact O-N 3.42Å; V167-V170 PolarHBondContact O-N 3.19Å; V170-A172 VanDerWaalsContact C-N 3.28Å; V170-A172 PolarHBondContact O-N 3.33Å; V170-T173 PolarHBondContact O-N 3.03Å; V170-Y174 HydrophobicContact CG1-CD2 3.77Å; V170-Y174 HydrophobicContact CG1-CE2 3.97Å; V170-Y174 WeakPolarHBondContact O-CB 3.33Å; V170-Y174 VanDerWaalsContact O-CD2 3.31Å; V170-Y174 WeakPolarHBondContact O-CD2 2.96Å; V170-Y174 PolarHBondContact O-N 2.91Å; V170-I413 HydrophobicContact CG2-CD1 3.91Å
171	F	91.9	Very high	90.7	Very high	30 Å²	30	27.7 Å²	27.7	13%	0.132	15%	0.149	C	C	.	.	H	α-helix	trans	-52.1	-48.5	170.7	166.2	-99.1	0	0	0	111.6	V167 A168 Y169 Y174 L175 V193 C197 G352 C355 F356	V167-F171 PolarHBondContact O-N 3.44Å; A168-F171 WeakPolarHBondContact O-CB 3.07Å; A168-F171 PolarHBondContact O-N 3.04Å; Y169-F171 VanDerWaalsContact C-N 3.34Å; Y169-F171 PolarHBondContact O-N 3.08Å; F171-Y174 PolarHBondContact O-N 3.47Å; F171-L175 HydrophobicContact CE1-CD2 4.05Å; F171-L175 HydrophobicContact CZ-CD2 3.88Å; F171-L175 VanDerWaalsContact O-CB 3.28Å; F171-L175 WeakPolarHBondContact O-CB 3.48Å; F171-L175 PolarHBondContact O-N 2.98Å; F171-V193 HydrophobicContact CE1-CG1 4.24Å; F171-C197 HydrophobicContact CD1-CB 3.69Å; F171-C197 VanDerWaalsContact CD1-SG 3.57Å; F171-C197 HydrophobicContact CE1-CB 3.74Å; F171-G352 VanDerWaalsContact CD2-O 3.31Å; F171-G352 WeakPolarHBondContact CD2-O 3.39Å; F171-C355 HydrophobicContact CB-CB 3.66Å; F171-C355 HydrophobicContact CD2-CB 4.5Å; F171-F356 HydrophobicContact CD2-CB 4.37Å; F171-F356 HydrophobicContact CE2-CB 4.42Å; F171-F356 HydrophobicContact CE2-CD2 4.35Å; F171-F356 HydrophobicContact CZ-CD2 4.44Å
172	A	93.6	Very high	90.2	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-64.5	-46.2	-179.1	0	0	0	0	0	112.6	A168 Y169 V170 Y174 L175 L176 A190 V193 A194	A168-A172 PolarHBondContact O-N 3.01Å; A168-A172 VanDerWaalsContact O-N 3.09Å; Y169-A172 WeakPolarHBondContact O-CB 3.5Å; Y169-A172 PolarHBondContact O-N 3.03Å; Y169-A172 VanDerWaalsContact O-N 3.07Å; V170-A172 VanDerWaalsContact C-N 3.28Å; V170-A172 PolarHBondContact O-N 3.33Å; A172-Y174 PolarHBondContact O-N 3.3Å; A172-L175 PolarHBondContact O-N 3.14Å; A172-L176 WeakPolarHBondContact O-CB 3.36Å; A172-L176 VanDerWaalsContact O-CG 3.27Å; A172-L176 WeakPolarHBondContact O-CG 3.45Å; A172-L176 PolarHBondContact O-N 2.99Å; A172-A190 HydrophobicContact CB-CB 4.32Å; A172-A190 WeakPolarHBondContact CB-O 3.23Å; A172-V193 HydrophobicContact CB-CB 3.76Å; A172-V193 HydrophobicContact CB-CG1 3.66Å; A172-A194 HydrophobicContact CB-CB 4.11Å
173	T	91.1	Very high	89.9	Confident	10 Å²	10	37.4 Å²	37.4	6%	0.061	21%	0.209	C	C	.	.	H	α-helix	trans	-59.7	-46.3	177.6	-55.7	0	0	0	0	111.2	Y169 V170 L175 L176 K177 V185 E329	Y169-T173 WeakPolarHBondContact CE1-OG1 3.49Å; Y169-T173 PolarHBondContact O-N 3.45Å; Y169-T173 PolarHBondContact O-OG1 3.25Å; V170-T173 PolarHBondContact O-N 3.03Å; T173-L175 VanDerWaalsContact C-N 3.35Å; T173-L175 PolarHBondContact O-N 3.31Å; T173-L176 PolarHBondContact O-N 3.5Å; T173-K177 VanDerWaalsContact O-CB 3.31Å; T173-K177 WeakPolarHBondContact O-CB 3.42Å; T173-K177 PolarHBondContact O-N 3.31Å; T173-V185 HydrophobicContact CG2-CG2 4.39Å; T173-E329 HydrophobicContact CG2-CB 3.93Å
174	Y	89.5	Confident	89.7	Confident	2 Å²	2	40.5 Å²	40.5	1%	0.008	23%	0.229	C	C	.	.	H	α-helix	trans	-67.2	-33.9	179	-89.8	-96.7	0	0	0	113.4	F88 V170 F171 A172 P178 A330 A332 V333 P348 V351	F88-Y174 HydrophobicContact CB-CE2 4.17Å; F88-Y174 PolarHBondContact O-OH 2.98Å; V170-Y174 HydrophobicContact CG1-CD2 3.77Å; V170-Y174 HydrophobicContact CG1-CE2 3.97Å; V170-Y174 WeakPolarHBondContact O-CB 3.33Å; V170-Y174 VanDerWaalsContact O-CD2 3.31Å; V170-Y174 WeakPolarHBondContact O-CD2 2.96Å; V170-Y174 PolarHBondContact O-N 2.91Å; F171-Y174 PolarHBondContact O-N 3.47Å; A172-Y174 PolarHBondContact O-N 3.3Å; Y174-P178 VanDerWaalsContact O-CD 3.27Å; Y174-P178 WeakPolarHBondContact O-CD 3.23Å; Y174-A330 HydrophobicContact CD1-CB 4.21Å; Y174-A330 HydrophobicContact CD2-CB 4.23Å; Y174-A330 HydrophobicContact CE1-CB 3.86Å; Y174-A330 HydrophobicContact CE2-CB 3.89Å; Y174-A330 HydrophobicContact CG-CB 4.39Å; Y174-A330 WeakPolarHBondContact OH-CA 3.2Å; Y174-A332 HydrophobicContact CE1-CB 4.05Å; Y174-V333 HydrophobicContact CD1-CG2 3.59Å; Y174-V333 HydrophobicContact CE1-CG2 3.73Å; Y174-P348 WeakPolarHBondContact O-CB 3.3Å; Y174-V351 HydrophobicContact CD1-CB 3.68Å; Y174-V351 HydrophobicContact CD1-CG1 3.36Å; Y174-V351 HydrophobicContact CD1-CG2 4.15Å; Y174-V351 HydrophobicContact CD2-CG1 4.08Å; Y174-V351 HydrophobicContact CE1-CB 4.03Å; Y174-V351 HydrophobicContact CE1-CG1 3.59Å; Y174-V351 HydrophobicContact CE1-CG2 4.04Å; Y174-V351 HydrophobicContact CE2-CG1 4.28Å; Y174-V351 HydrophobicContact CG-CB 4.28Å; Y174-V351 HydrophobicContact CG-CG1 3.61Å
175	L	91.3	Very high	89.6	Confident	89 Å²	89	40.9 Å²	40.9	47%	0.466	23%	0.232	S	C	.	.	H	α-helix	trans	-70.6	-37.5	175.9	-176.5	63.7	0	0	0	112	F171 A172 T173 V193	F171-L175 HydrophobicContact CE1-CD2 4.05Å; F171-L175 HydrophobicContact CZ-CD2 3.88Å; F171-L175 VanDerWaalsContact O-CB 3.28Å; F171-L175 WeakPolarHBondContact O-CB 3.48Å; F171-L175 PolarHBondContact O-N 2.98Å; A172-L175 PolarHBondContact O-N 3.14Å; T173-L175 VanDerWaalsContact C-N 3.35Å; T173-L175 PolarHBondContact O-N 3.31Å; L175-V193 HydrophobicContact CD2-CG1 4.09Å
176	L	91.7	Very high	89.5	Confident	24 Å²	24	43.9 Å²	43.9	13%	0.126	25%	0.251	C	S	.	.	H	α-helix	trans	-86.2	-26	-176.9	-67.4	174.4	0	0	0	113.2	A172 T173 P178 I179 F180 V185 A190 V193	A172-L176 WeakPolarHBondContact O-CB 3.36Å; A172-L176 VanDerWaalsContact O-CG 3.27Å; A172-L176 WeakPolarHBondContact O-CG 3.45Å; A172-L176 PolarHBondContact O-N 2.99Å; T173-L176 PolarHBondContact O-N 3.5Å; L176-P178 VanDerWaalsContact C-CD 3.48Å; L176-I179 HydrophobicContact CD2-CD1 4.28Å; L176-I179 WeakPolarHBondContact O-CA 3.39Å; L176-I179 WeakPolarHBondContact O-CB 3.24Å; L176-I179 PolarHBondContact O-N 3.36Å; L176-F180 HydrophobicContact CB-CD2 4.44Å; L176-F180 PolarHBondContact O-N 2.99Å; L176-F180 VanDerWaalsContact O-N 3.14Å; L176-V185 HydrophobicContact CB-CG1 3.69Å; L176-V185 HydrophobicContact CB-CG2 4.22Å; L176-V185 HydrophobicContact CD1-CG1 3.67Å; L176-V185 HydrophobicContact CG-CG1 4.35Å; L176-A190 HydrophobicContact CD1-CB 4.4Å; L176-V193 HydrophobicContact CD1-CG2 4.16Å; L176-V193 HydrophobicContact CD2-CG2 4.43Å
177	K	88.6	Confident	89.4	Confident	17 Å²	17	47.8 Å²	47.8	7%	0.074	27%	0.269	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-39.4	-176.5	-170.6	67.9	-177.6	166.2	0	114.2	T173 I179 F180 C183 V185 A330 V333	T173-K177 VanDerWaalsContact O-CB 3.31Å; T173-K177 WeakPolarHBondContact O-CB 3.42Å; T173-K177 PolarHBondContact O-N 3.31Å; K177-I179 PolarHBondContact O-N 3.36Å; K177-F180 PolarHBondContact NZ-O 3.45Å; K177-F180 CarbonylContact O-C 3.56Å; K177-F180 PolarHBondContact O-N 3.3Å; K177-F180 VanDerWaalsContact O-N 3.08Å; K177-F180 VanDerWaalsContact O-O 3.1Å; K177-C183 PolarHBondContact NZ-O 3.41Å; K177-C183 VanDerWaalsContact NZ-O 3.12Å; K177-V185 HydrophobicContact CB-CG2 4.4Å; K177-V185 HydrophobicContact CD-CG2 4.12Å; K177-A330 HydrophobicContact CB-CB 4.25Å; K177-A330 HydrophobicContact CG-CB 4.02Å; K177-V333 HydrophobicContact CG-CG1 4.33Å
178	P	86.8	Confident	89.4	Confident	66 Å²	66	55 Å²	55	43%	0.429	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-25.7	174.9	-25.9	36.7	0	0	0	114.2	Y174 L176 P348	Y174-P178 VanDerWaalsContact O-CD 3.27Å; Y174-P178 WeakPolarHBondContact O-CD 3.23Å; L176-P178 VanDerWaalsContact C-CD 3.48Å; P178-P348 HydrophobicContact CG-CB 3.78Å; P178-P348 HydrophobicContact CG-CG 3.67Å
179	I	89.3	Confident	89.3	Confident	121 Å²	121	56.3 Å²	56.3	62%	0.621	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82	-30.4	176.7	-54.2	171.2	0	0	0	110.5	L176 K177 P181	L176-I179 HydrophobicContact CD2-CD1 4.28Å; L176-I179 WeakPolarHBondContact O-CA 3.39Å; L176-I179 WeakPolarHBondContact O-CB 3.24Å; L176-I179 PolarHBondContact O-N 3.36Å; K177-I179 PolarHBondContact O-N 3.36Å; I179-P181 WeakPolarHBondContact O-CD 3.43Å
180	F	88.4	Confident	89.3	Confident	64 Å²	64	54.4 Å²	54.4	28%	0.281	31%	0.308	S	S	.	.	S	Bend	trans	-115.1	66	176.4	-61.1	-83.8	0	0	0	111.1	L176 K177 V182 V185 P186	L176-F180 HydrophobicContact CB-CD2 4.44Å; L176-F180 PolarHBondContact O-N 2.99Å; L176-F180 VanDerWaalsContact O-N 3.14Å; K177-F180 PolarHBondContact NZ-O 3.45Å; K177-F180 CarbonylContact O-C 3.56Å; K177-F180 PolarHBondContact O-N 3.3Å; K177-F180 VanDerWaalsContact O-N 3.08Å; K177-F180 VanDerWaalsContact O-O 3.1Å; F180-V182 PolarHBondContact O-N 3.5Å; F180-V185 HydrophobicContact CB-CG2 4.39Å; F180-P186 HydrophobicContact CE1-CG 4.08Å; F180-P186 HydrophobicContact CE2-CG 4.48Å; F180-P186 HydrophobicContact CZ-CG 4.01Å
181	P	80.4	Confident	89.5	Confident	76 Å²	76	55.7 Å²	55.7	49%	0.494	31%	0.314	S	S	.	.	S	Bend	trans	-67.7	-38.4	-171.9	24.2	-32.7	0	0	0	112.7	I179	I179-P181 WeakPolarHBondContact O-CD 3.43Å
182	V	82.8	Confident	89.7	Confident	145 Å²	145	60.2 Å²	60.2	88%	0.879	34%	0.339	S	S	*	.	S	Bend	trans	-100.6	-24.3	-173.2	-173.2	0	0	0	0	112.5	F180	F180-V182 PolarHBondContact O-N 3.5Å
183	C	86.9	Confident	89.8	Confident	59 Å²	59	61.9 Å²	61.9	40%	0.399	35%	0.349	S	S	.	.	S	Bend	trans	-104.3	158	-179.3	41.3	0	0	0	0	111.8	K177	K177-C183 PolarHBondContact NZ-O 3.41Å; K177-C183 VanDerWaalsContact NZ-O 3.12Å
184	P	86.4	Confident	90	Very high	91 Å²	91	61.4 Å²	61.4	59%	0.591	35%	0.346	S	S	*	.	P	Polyproline II helix	trans	-64.1	146.2	171	27.5	-34.2	0	0	0	110.2
185	V	89.4	Confident	90.3	Very high	9 Å²	9	62.5 Å²	62.5	6%	0.055	35%	0.353	C	S	.	.	P	Polyproline II helix	trans	-68.1	130.2	177.5	177	0	0	0	0	108.6	T173 L176 K177 F180 E187 A190 E329	T173-V185 HydrophobicContact CG2-CG2 4.39Å; L176-V185 HydrophobicContact CB-CG1 3.69Å; L176-V185 HydrophobicContact CB-CG2 4.22Å; L176-V185 HydrophobicContact CD1-CG1 3.67Å; L176-V185 HydrophobicContact CG-CG1 4.35Å; K177-V185 HydrophobicContact CB-CG2 4.4Å; K177-V185 HydrophobicContact CD-CG2 4.12Å; F180-V185 HydrophobicContact CB-CG2 4.39Å; V185-E187 PolarHBondContact O-N 3.13Å; V185-E187 VanDerWaalsContact O-N 3.11Å; V185-A190 HydrophobicContact CG1-CB 4.12Å; V185-E329 PolarHBondContact N-OE2 3.35Å
186	P	91.9	Very high	90.6	Very high	64 Å²	64	63.7 Å²	63.7	42%	0.416	36%	0.36	S	S	.	.	P	Polyproline II helix	trans	-58.1	120.3	176.4	-24.6	33.8	0	0	0	111.2	F180 Q188 G189 A190	F180-P186 HydrophobicContact CE1-CG 4.08Å; F180-P186 HydrophobicContact CE2-CG 4.48Å; F180-P186 HydrophobicContact CZ-CG 4.01Å; P186-Q188 VanDerWaalsContact C-N 3.29Å; P186-Q188 PolarHBondContact O-N 3.41Å; P186-G189 WeakPolarHBondContact O-CA 3.48Å; P186-G189 PolarHBondContact O-N 2.81Å; P186-A190 PolarHBondContact O-N 2.88Å
187	E	89.1	Confident	90.7	Very high	82 Å²	82	62.9 Å²	62.9	38%	0.383	36%	0.356	S	S	.	.	H	α-helix	trans	-55.2	-43.3	-173.9	-170.5	-168	156.1	0	0	112.4	V185 G189 A190 K191	V185-E187 PolarHBondContact O-N 3.13Å; V185-E187 VanDerWaalsContact O-N 3.11Å; E187-G189 VanDerWaalsContact C-N 3.3Å; E187-G189 PolarHBondContact O-N 3.31Å; E187-A190 PolarHBondContact O-N 2.88Å; E187-K191 HydrophobicContact CG-CD 4.31Å; E187-K191 WeakPolarHBondContact O-CG 3.44Å; E187-K191 PolarHBondContact O-N 3.09Å; E187-K191 WeakPolarHBondContact OE1-CE 3.26Å; E187-K191 IonicContact OE1-NZ 2.63Å; E187-K191 PolarHBondContact OE1-NZ 3.47Å
188	Q	90.7	Very high	90.9	Very high	162 Å²	162	62.1 Å²	62.1	76%	0.757	35%	0.352	S	S	*	.	H	α-helix	trans	-61.7	-38.4	176.8	-66	-179.3	-12.2	0	0	112.1	P186 L192	P186-Q188 VanDerWaalsContact C-N 3.29Å; P186-Q188 PolarHBondContact O-N 3.41Å; Q188-L192 WeakPolarHBondContact O-CB 3.36Å; Q188-L192 VanDerWaalsContact O-CG 3.27Å; Q188-L192 WeakPolarHBondContact O-CG 3.47Å; Q188-L192 PolarHBondContact O-N 3.04Å
189	G	92.8	Very high	91.3	Very high	27 Å²	27	63.1 Å²	63.1	28%	0.278	35%	0.354	S	S	.	.	H	α-helix	trans	-65.8	-45.8	176.3	0	0	0	0	0	111.7	P186 E187 K191 L192 V193	P186-G189 WeakPolarHBondContact O-CA 3.48Å; P186-G189 PolarHBondContact O-N 2.81Å; E187-G189 VanDerWaalsContact C-N 3.3Å; E187-G189 PolarHBondContact O-N 3.31Å; G189-K191 PolarHBondContact O-N 3.42Å; G189-L192 PolarHBondContact O-N 3.42Å; G189-V193 WeakPolarHBondContact O-CG2 3.38Å; G189-V193 PolarHBondContact O-N 3.35Å
190	A	92.7	Very high	91.5	Very high	0 Å²	0	61.3 Å²	61.3	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-60.6	-45.2	175.9	0	0	0	0	0	111.7	Y169 A172 L176 V185 P186 E187 L192 V193 A194	Y169-A190 HydrophobicContact CD2-CB 4.47Å; Y169-A190 HydrophobicContact CE2-CB 3.87Å; A172-A190 HydrophobicContact CB-CB 4.32Å; A172-A190 WeakPolarHBondContact CB-O 3.23Å; L176-A190 HydrophobicContact CD1-CB 4.4Å; V185-A190 HydrophobicContact CG1-CB 4.12Å; P186-A190 PolarHBondContact O-N 2.88Å; E187-A190 PolarHBondContact O-N 2.88Å; A190-L192 PolarHBondContact O-N 2.86Å; A190-V193 PolarHBondContact O-N 3.36Å; A190-A194 VanDerWaalsContact O-CB 3.31Å; A190-A194 WeakPolarHBondContact O-CB 3.5Å; A190-A194 PolarHBondContact O-N 3.12Å
191	K	94.6	Very high	91.6	Very high	32 Å²	32	58.4 Å²	58.4	14%	0.139	33%	0.332	C	S	.	.	H	α-helix	trans	-59.4	-46.9	176.3	-74.2	175.6	170	175	0	112.6	Y169 E187 G189 V193 A194 C195 A408 S410	Y169-K191 HydrophobicContact CD2-CG 4.33Å; Y169-K191 HydrophobicContact CE2-CG 4Å; E187-K191 HydrophobicContact CG-CD 4.31Å; E187-K191 WeakPolarHBondContact O-CG 3.44Å; E187-K191 PolarHBondContact O-N 3.09Å; E187-K191 WeakPolarHBondContact OE1-CE 3.26Å; E187-K191 IonicContact OE1-NZ 2.63Å; E187-K191 PolarHBondContact OE1-NZ 3.47Å; G189-K191 PolarHBondContact O-N 3.42Å; K191-V193 PolarHBondContact O-N 3.3Å; K191-A194 WeakPolarHBondContact O-CB 3.28Å; K191-A194 PolarHBondContact O-N 3.25Å; K191-C195 PolarHBondContact O-N 3.46Å; K191-C195 PolarHBondContact O-SG 2.88Å; K191-A408 WeakPolarHBondContact CD-O 3.36Å; K191-A408 WeakPolarHBondContact CE-O 3.42Å; K191-S410 WeakPolarHBondContact CE-O 3.45Å; K191-S410 PolarHBondContact NZ-O 3.11Å
192	L	95.6	Very high	92.1	Very high	125 Å²	125	55.2 Å²	55.2	65%	0.654	31%	0.311	S	S	*	.	H	α-helix	trans	-63.5	-42.6	179.5	-72.6	172.4	0	0	0	112.1	Q188 G189 A190 A194 C195 L196	Q188-L192 WeakPolarHBondContact O-CB 3.36Å; Q188-L192 VanDerWaalsContact O-CG 3.27Å; Q188-L192 WeakPolarHBondContact O-CG 3.47Å; Q188-L192 PolarHBondContact O-N 3.04Å; G189-L192 PolarHBondContact O-N 3.42Å; A190-L192 PolarHBondContact O-N 2.86Å; L192-A194 VanDerWaalsContact C-N 3.34Å; L192-C195 PolarHBondContact O-N 3.31Å; L192-L196 WeakPolarHBondContact O-CB 3.49Å; L192-L196 PolarHBondContact O-N 3.47Å
193	V	95.9	Very high	92.5	Very high	35 Å²	35	55 Å²	55	21%	0.212	30%	0.299	C	S	.	.	H	α-helix	trans	-66.5	-37.5	176.2	172.8	0	0	0	0	111.2	F171 A172 L175 L176 G189 A190 K191 L196 C197	F171-V193 HydrophobicContact CE1-CG1 4.24Å; A172-V193 HydrophobicContact CB-CB 3.76Å; A172-V193 HydrophobicContact CB-CG1 3.66Å; L175-V193 HydrophobicContact CD2-CG1 4.09Å; L176-V193 HydrophobicContact CD1-CG2 4.16Å; L176-V193 HydrophobicContact CD2-CG2 4.43Å; G189-V193 WeakPolarHBondContact O-CG2 3.38Å; G189-V193 PolarHBondContact O-N 3.35Å; A190-V193 PolarHBondContact O-N 3.36Å; K191-V193 PolarHBondContact O-N 3.3Å; V193-L196 PolarHBondContact O-N 3Å; V193-C197 WeakPolarHBondContact O-CB 3.47Å; V193-C197 PolarHBondContact O-N 3.45Å
194	A	95.3	Very high	92.5	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-63.5	-46.7	174.3	0	0	0	0	0	111.7	A168 A172 A190 K191 L192 L196 C197 I198	A168-A194 HydrophobicContact CB-CB 4.13Å; A168-A194 WeakPolarHBondContact O-CB 3.38Å; A172-A194 HydrophobicContact CB-CB 4.11Å; A190-A194 VanDerWaalsContact O-CB 3.31Å; A190-A194 WeakPolarHBondContact O-CB 3.5Å; A190-A194 PolarHBondContact O-N 3.12Å; K191-A194 WeakPolarHBondContact O-CB 3.28Å; K191-A194 PolarHBondContact O-N 3.25Å; L192-A194 VanDerWaalsContact C-N 3.34Å; A194-L196 VanDerWaalsContact C-N 3.33Å; A194-L196 PolarHBondContact O-N 3.14Å; A194-C197 WeakPolarHBondContact O-CB 3.33Å; A194-C197 PolarHBondContact O-N 3.49Å; A194-I198 WeakPolarHBondContact O-CD1 3.48Å; A194-I198 WeakPolarHBondContact O-CG1 3.49Å; A194-I198 PolarHBondContact O-N 2.99Å
195	C	96	Very high	92.5	Very high	24 Å²	24	50.3 Å²	50.3	16%	0.162	27%	0.267	C	S	.	.	H	α-helix	trans	-59.9	-42.8	174.5	-69.6	0	0	0	0	111.8	K191 L192 C197 I198 L199 L405 A408	K191-C195 PolarHBondContact O-N 3.46Å; K191-C195 PolarHBondContact O-SG 2.88Å; L192-C195 PolarHBondContact O-N 3.31Å; C195-C197 VanDerWaalsContact C-N 3.34Å; C195-C197 PolarHBondContact O-N 2.93Å; C195-I198 PolarHBondContact O-N 3.18Å; C195-L199 WeakPolarHBondContact O-CB 3.36Å; C195-L199 WeakPolarHBondContact O-CG 3.27Å; C195-L199 PolarHBondContact O-N 3.38Å; C195-L405 HydrophobicContact CB-CD2 3.75Å; C195-A408 VanDerWaalsContact SG-CB 3.59Å
196	L	96.4	Very high	92.3	Very high	115 Å²	115	50.6 Å²	50.6	60%	0.602	27%	0.269	S	S	*	.	H	α-helix	trans	-61.6	-42.5	175.5	-176.9	67.4	0	0	0	111.5	L192 V193 A194 L199 L200	L192-L196 WeakPolarHBondContact O-CB 3.49Å; L192-L196 PolarHBondContact O-N 3.47Å; V193-L196 PolarHBondContact O-N 3Å; A194-L196 VanDerWaalsContact C-N 3.33Å; A194-L196 PolarHBondContact O-N 3.14Å; L196-L199 PolarHBondContact O-N 3.02Å; L196-L200 VanDerWaalsContact O-CB 3.23Å; L196-L200 WeakPolarHBondContact O-CB 3.4Å; L196-L200 PolarHBondContact O-N 3.23Å
197	C	93.8	Very high	92.1	Very high	7 Å²	7	55 Å²	55	5%	0.047	28%	0.278	C	S	.	.	H	α-helix	trans	-59.5	-47.7	175.8	-178.6	0	0	0	0	111.5	F171 V193 A194 C195 L200 L201	F171-C197 HydrophobicContact CD1-CB 3.69Å; F171-C197 VanDerWaalsContact CD1-SG 3.57Å; F171-C197 HydrophobicContact CE1-CB 3.74Å; V193-C197 WeakPolarHBondContact O-CB 3.47Å; V193-C197 PolarHBondContact O-N 3.45Å; A194-C197 WeakPolarHBondContact O-CB 3.33Å; A194-C197 PolarHBondContact O-N 3.49Å; C195-C197 VanDerWaalsContact C-N 3.34Å; C195-C197 PolarHBondContact O-N 2.93Å; C197-L200 PolarHBondContact O-N 3.48Å; C197-L201 WeakPolarHBondContact O-CB 3.42Å; C197-L201 WeakPolarHBondContact O-CG 3.42Å; C197-L201 PolarHBondContact O-N 3.27Å
198	I	94.3	Very high	91.6	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-61.3	-49.7	177.3	-66.9	155.8	0	0	0	110.7	A168 A194 C195 L200 L201 T202 T404	A168-I198 HydrophobicContact CB-CD1 3.68Å; A168-I198 HydrophobicContact CB-CG1 3.61Å; A194-I198 WeakPolarHBondContact O-CD1 3.48Å; A194-I198 WeakPolarHBondContact O-CG1 3.49Å; A194-I198 PolarHBondContact O-N 2.99Å; C195-I198 PolarHBondContact O-N 3.18Å; I198-L200 PolarHBondContact O-N 3.37Å; I198-L201 PolarHBondContact O-N 3.5Å; I198-T202 WeakPolarHBondContact O-CB 3.16Å; I198-T202 PolarHBondContact O-N 3.08Å; I198-T202 PolarHBondContact O-OG1 3.39Å; I198-T404 HydrophobicContact CD1-CG2 3.47Å; I198-T404 VanDerWaalsContact CD1-CG2 3.47Å; I198-T404 HydrophobicContact CG1-CG2 4.11Å; I198-T404 HydrophobicContact CG2-CG2 4.25Å
199	L	95.4	Very high	90.6	Very high	87 Å²	87	46.9 Å²	46.9	46%	0.455	25%	0.246	S	C	.	.	H	α-helix	trans	-60.5	-43.9	-179.9	-76.3	166.5	0	0	0	112	C195 L196 T202 F203 L405	C195-L199 WeakPolarHBondContact O-CB 3.36Å; C195-L199 WeakPolarHBondContact O-CG 3.27Å; C195-L199 PolarHBondContact O-N 3.38Å; L196-L199 PolarHBondContact O-N 3.02Å; L199-T202 PolarHBondContact O-N 3.49Å; L199-F203 WeakPolarHBondContact O-CB 3.35Å; L199-F203 PolarHBondContact O-N 3.41Å; L199-L405 HydrophobicContact CD2-CD1 4.12Å; L199-L405 HydrophobicContact CG-CD1 4.44Å
200	L	92.8	Very high	89.6	Confident	84 Å²	84	52.9 Å²	52.9	44%	0.44	27%	0.265	S	S	.	.	H	α-helix	trans	-64	-44.9	177.7	-177.5	142.9	0	0	0	111.2	L196 C197 I198 F203 V204 F356	L196-L200 VanDerWaalsContact O-CB 3.23Å; L196-L200 WeakPolarHBondContact O-CB 3.4Å; L196-L200 PolarHBondContact O-N 3.23Å; C197-L200 PolarHBondContact O-N 3.48Å; I198-L200 PolarHBondContact O-N 3.37Å; L200-F203 PolarHBondContact O-N 3.23Å; L200-V204 HydrophobicContact CD2-CG2 4.37Å; L200-V204 VanDerWaalsContact O-CG2 3.3Å; L200-V204 WeakPolarHBondContact O-CG2 3.22Å; L200-V204 PolarHBondContact O-N 2.89Å; L200-F356 HydrophobicContact CD2-CE2 3.88Å; L200-F356 HydrophobicContact CD2-CZ 3.71Å
201	L	89.8	Confident	88.5	Confident	2 Å²	2	55 Å²	55	1%	0.01	28%	0.282	C	S	.	.	H	α-helix	trans	-65.1	-43.5	177.2	-83	174.4	0	0	0	112.1	C197 I198 F203 V204 N205 F356 V359 N360 L363	C197-L201 WeakPolarHBondContact O-CB 3.42Å; C197-L201 WeakPolarHBondContact O-CG 3.42Å; C197-L201 PolarHBondContact O-N 3.27Å; I198-L201 PolarHBondContact O-N 3.5Å; L201-F203 VanDerWaalsContact C-N 3.32Å; L201-F203 PolarHBondContact O-N 3.47Å; L201-V204 PolarHBondContact O-N 2.9Å; L201-N205 WeakPolarHBondContact O-CB 3.17Å; L201-N205 PolarHBondContact O-N 2.88Å; L201-N205 PolarHBondContact O-ND2 3.27Å; L201-F356 HydrophobicContact CD1-CD1 4.45Å; L201-F356 HydrophobicContact CD1-CD2 4.07Å; L201-F356 HydrophobicContact CD1-CE1 4.49Å; L201-F356 HydrophobicContact CD1-CE2 4.06Å; L201-F356 HydrophobicContact CD1-CG 4.28Å; L201-F356 HydrophobicContact CD1-CZ 4.3Å; L201-F356 HydrophobicContact CD2-CD1 3.88Å; L201-F356 HydrophobicContact CD2-CD2 4.43Å; L201-F356 HydrophobicContact CD2-CE1 3.27Å; L201-F356 HydrophobicContact CD2-CE2 3.87Å; L201-F356 HydrophobicContact CD2-CG 4.45Å; L201-F356 HydrophobicContact CD2-CZ 3.26Å; L201-F356 HydrophobicContact CG-CD2 4.24Å; L201-F356 HydrophobicContact CG-CE1 4.08Å; L201-F356 HydrophobicContact CG-CE2 3.72Å; L201-F356 HydrophobicContact CG-CZ 3.64Å; L201-V359 HydrophobicContact CD1-CB 3.59Å; L201-V359 HydrophobicContact CD1-CG1 3.52Å; L201-N360 HydrophobicContact CD2-CB 3.89Å; L201-L363 HydrophobicContact CB-CD1 3.85Å
202	T	91.3	Very high	87.1	Confident	9 Å²	9	53.6 Å²	53.6	6%	0.055	28%	0.277	C	S	.	.	H	α-helix	trans	-59	-45.6	173.9	-60.5	0	0	0	0	110.5	I198 L199 V204 N205 C206 L397 C401	I198-T202 WeakPolarHBondContact O-CB 3.16Å; I198-T202 PolarHBondContact O-N 3.08Å; I198-T202 PolarHBondContact O-OG1 3.39Å; L199-T202 PolarHBondContact O-N 3.49Å; T202-V204 PolarHBondContact O-N 2.97Å; T202-N205 PolarHBondContact O-N 2.91Å; T202-C206 WeakPolarHBondContact O-CB 3.19Å; T202-C206 PolarHBondContact O-N 3.34Å; T202-C206 PolarHBondContact O-SG 3.44Å; T202-L397 HydrophobicContact CG2-CB 4.28Å; T202-C401 HydrophobicContact CG2-CB 3.75Å; T202-C401 WeakPolarHBondContact OG1-CB 3.38Å; T202-C401 PolarHBondContact OG1-SG 3Å; T202-C401 VanDerWaalsContact OG1-SG 3.41Å
203	F	91.5	Very high	85.8	Confident	141 Å²	141	50.2 Å²	50.2	62%	0.618	26%	0.262	S	S	*	.	H	α-helix	trans	-58.7	-47.5	177	176.8	-98.9	0	0	0	112.3	L199 L200 L201 N205 C206 Y207	L199-F203 WeakPolarHBondContact O-CB 3.35Å; L199-F203 PolarHBondContact O-N 3.41Å; L200-F203 PolarHBondContact O-N 3.23Å; L201-F203 VanDerWaalsContact C-N 3.32Å; L201-F203 PolarHBondContact O-N 3.47Å; F203-N205 VanDerWaalsContact C-N 3.35Å; F203-N205 PolarHBondContact O-N 3.25Å; F203-C206 WeakPolarHBondContact O-CB 3.47Å; F203-C206 PolarHBondContact O-N 2.98Å; F203-Y207 PolarHBondContact O-N 3.24Å
204	V	87.8	Confident	84.6	Confident	48 Å²	48	57.7 Å²	57.7	29%	0.291	29%	0.286	S	S	.	.	H	α-helix	trans	-62.1	-42.5	177.6	173.2	0	0	0	0	111.3	L200 L201 T202 C206 Y207 S208	L200-V204 HydrophobicContact CD2-CG2 4.37Å; L200-V204 VanDerWaalsContact O-CG2 3.3Å; L200-V204 WeakPolarHBondContact O-CG2 3.22Å; L200-V204 PolarHBondContact O-N 2.89Å; L201-V204 PolarHBondContact O-N 2.9Å; T202-V204 PolarHBondContact O-N 2.97Å; V204-C206 VanDerWaalsContact C-N 3.33Å; V204-C206 PolarHBondContact O-N 2.92Å; V204-Y207 PolarHBondContact O-N 3.48Å; V204-S208 PolarHBondContact O-N 2.98Å
205	N	84.9	Confident	83.3	Confident	4 Å²	4	60.5 Å²	60.5	2%	0.021	30%	0.303	C	S	.	.	H	α-helix	trans	-67.6	-32.4	177.6	-81.7	-83.5	0	0	0	112.8	L201 T202 F203 N360 T392 L397	L201-N205 WeakPolarHBondContact O-CB 3.17Å; L201-N205 PolarHBondContact O-N 2.88Å; L201-N205 PolarHBondContact O-ND2 3.27Å; T202-N205 PolarHBondContact O-N 2.91Å; F203-N205 VanDerWaalsContact C-N 3.35Å; F203-N205 PolarHBondContact O-N 3.25Å; N205-N360 PolarHBondContact ND2-OD1 2.74Å; N205-T392 VanDerWaalsContact O-CG2 3.26Å; N205-T392 WeakPolarHBondContact O-CG2 3.47Å; N205-L397 HydrophobicContact CB-CD1 3.96Å; N205-L397 HydrophobicContact CB-CD2 4.4Å
206	C	86.7	Confident	81.9	Confident	15 Å²	15	62.4 Å²	62.4	10%	0.101	31%	0.309	C	S	.	.	H	α-helix	trans	-68.6	-35.7	172.4	-73.8	0	0	0	0	111.9	T202 F203 V204 L390 T392 L394	T202-C206 WeakPolarHBondContact O-CB 3.19Å; T202-C206 PolarHBondContact O-N 3.34Å; T202-C206 PolarHBondContact O-SG 3.44Å; F203-C206 WeakPolarHBondContact O-CB 3.47Å; F203-C206 PolarHBondContact O-N 2.98Å; V204-C206 VanDerWaalsContact C-N 3.33Å; V204-C206 PolarHBondContact O-N 2.92Å; C206-L390 WeakPolarHBondContact O-CD1 3.25Å; C206-T392 WeakPolarHBondContact O-CB 3.48Å; C206-T392 WeakPolarHBondContact O-CG2 3.34Å; C206-T392 PolarHBondContact O-OG1 2.87Å; C206-L394 HydrophobicContact CB-CD1 3.67Å
207	Y	86.9	Confident	80.6	Confident	156 Å²	156	62.5 Å²	62.5	61%	0.612	31%	0.311	S	S	*	.	H	α-helix	trans	-81.2	-47.1	-177.8	-169.8	-97.3	0	0	0	113.7	F203 V204	F203-Y207 PolarHBondContact O-N 3.24Å; V204-Y207 PolarHBondContact O-N 3.48Å
208	S	79.5	Confident	79.6	Confident	35 Å²	35	68.7 Å²	68.7	25%	0.245	34%	0.337	C	S	.	.			trans	-156	112.4	-179.3	-170.3	0	0	0	0	113.7	V204 K210 A211 A212	V204-S208 PolarHBondContact O-N 2.98Å; S208-K210 VanDerWaalsContact C-N 3.28Å; S208-K210 PolarHBondContact O-N 3.33Å; S208-A211 PolarHBondContact O-N 2.84Å; S208-A211 PolarHBondContact OG-N 2.65Å; S208-A212 PolarHBondContact O-N 3.21Å
209	V	67.9	Low	78.6	Confident	38 Å²	38	69.9 Å²	69.9	23%	0.23	34%	0.342	C	S	.	.	H	α-helix	trans	-59.5	-39.3	171.9	-173.5	0	0	0	0	111.6	A211 A212 T213 F364 T392	V209-A211 VanDerWaalsContact C-N 3.32Å; V209-A211 PolarHBondContact O-N 3.41Å; V209-A212 PolarHBondContact O-N 3.34Å; V209-T213 HydrophobicContact CG1-CG2 4.35Å; V209-T213 WeakPolarHBondContact O-CG2 3.47Å; V209-T213 PolarHBondContact O-N 3.21Å; V209-T213 PolarHBondContact O-OG1 2.72Å; V209-F364 HydrophobicContact CG1-CD2 4.1Å; V209-F364 HydrophobicContact CG1-CE2 3.53Å; V209-F364 HydrophobicContact CG1-CZ 4.49Å; V209-T392 HydrophobicContact CG2-CG2 3.49Å; V209-T392 VanDerWaalsContact CG2-CG2 3.49Å
210	K	71.9	Confident	77.4	Confident	154 Å²	154	67.4 Å²	67.4	67%	0.67	33%	0.334	S	S	*	.	H	α-helix	trans	-67.2	-33.1	-177.2	-66.6	179.8	-177.5	173.5	0	112.6	S208 T213 R214	S208-K210 VanDerWaalsContact C-N 3.28Å; S208-K210 PolarHBondContact O-N 3.33Å; K210-T213 PolarHBondContact O-OG1 3.25Å; K210-R214 WeakPolarHBondContact O-CG 3.42Å; K210-R214 PolarHBondContact O-N 3.09Å
211	A	69.5	Low	76.6	Confident	44 Å²	44	66 Å²	66	36%	0.364	34%	0.335	S	S	.	.	H	α-helix	trans	-70.1	-45.5	173.9	0	0	0	0	0	110.4	S208 V209 T213 R214 V215	S208-A211 PolarHBondContact O-N 2.84Å; S208-A211 PolarHBondContact OG-N 2.65Å; V209-A211 VanDerWaalsContact C-N 3.32Å; V209-A211 PolarHBondContact O-N 3.41Å; A211-T213 VanDerWaalsContact C-N 3.33Å; A211-T213 PolarHBondContact O-N 3.46Å; A211-R214 PolarHBondContact O-N 2.99Å; A211-V215 WeakPolarHBondContact O-CB 3.49Å; A211-V215 VanDerWaalsContact O-CG2 3.27Å; A211-V215 WeakPolarHBondContact O-CG2 3.36Å; A211-V215 PolarHBondContact O-N 3.26Å; A211-V215 VanDerWaalsContact O-N 3.16Å
212	A	65.7	Low	75.9	Confident	3 Å²	3	66.2 Å²	66.2	3%	0.025	34%	0.337	C	S	.	.	H	α-helix	trans	-58.8	-40.7	178.6	0	0	0	0	0	112.7	S208 V209 Q216 N360	S208-A212 PolarHBondContact O-N 3.21Å; V209-A212 PolarHBondContact O-N 3.34Å; A212-Q216 WeakPolarHBondContact O-CB 3.42Å; A212-Q216 PolarHBondContact O-N 3.46Å; A212-Q216 VanDerWaalsContact O-N 3.16Å; A212-N360 PolarHBondContact O-ND2 3.47Å; A212-N360 VanDerWaalsContact O-ND2 3.15Å
213	T	68.3	Low	75.2	Confident	54 Å²	54	66.3 Å²	66.3	33%	0.331	34%	0.337	S	S	.	.	H	α-helix	trans	-70.2	-43	179.5	53.9	0	0	0	0	113.2	V209 K210 A211 V215 Q216 D217	V209-T213 HydrophobicContact CG1-CG2 4.35Å; V209-T213 WeakPolarHBondContact O-CG2 3.47Å; V209-T213 PolarHBondContact O-N 3.21Å; V209-T213 PolarHBondContact O-OG1 2.72Å; K210-T213 PolarHBondContact O-OG1 3.25Å; A211-T213 VanDerWaalsContact C-N 3.33Å; A211-T213 PolarHBondContact O-N 3.46Å; T213-V215 VanDerWaalsContact C-N 3.31Å; T213-V215 PolarHBondContact O-N 2.9Å; T213-Q216 WeakPolarHBondContact O-CB 3.39Å; T213-Q216 PolarHBondContact O-N 2.86Å; T213-D217 PolarHBondContact O-N 3.31Å; T213-D217 VanDerWaalsContact O-N 3.16Å
214	R	70.8	Confident	74.8	Confident	191 Å²	191	63.5 Å²	63.5	72%	0.721	33%	0.328	S	S	*	.	H	α-helix	trans	-62.5	-39.1	177.2	-72.1	-178.6	-169.5	166.9	3	112.7	K210 A211 Q216 F218	K210-R214 WeakPolarHBondContact O-CG 3.42Å; K210-R214 PolarHBondContact O-N 3.09Å; A211-R214 PolarHBondContact O-N 2.99Å; R214-Q216 VanDerWaalsContact C-N 3.32Å; R214-F218 PolarHBondContact O-N 3.06Å
215	V	67.9	Low	74.5	Confident	60 Å²	60	66.6 Å²	66.6	36%	0.364	34%	0.342	S	S	.	.	H	α-helix	trans	-64.9	-39.7	177.8	168	0	0	0	0	110.5	A211 T213 F219 F356	A211-V215 WeakPolarHBondContact O-CB 3.49Å; A211-V215 VanDerWaalsContact O-CG2 3.27Å; A211-V215 WeakPolarHBondContact O-CG2 3.36Å; A211-V215 PolarHBondContact O-N 3.26Å; A211-V215 VanDerWaalsContact O-N 3.16Å; T213-V215 VanDerWaalsContact C-N 3.31Å; T213-V215 PolarHBondContact O-N 2.9Å; V215-F219 HydrophobicContact CB-CE2 4.42Å; V215-F219 HydrophobicContact CG1-CD2 3.76Å; V215-F219 HydrophobicContact CG1-CE1 4.45Å; V215-F219 HydrophobicContact CG1-CE2 3.04Å; V215-F219 HydrophobicContact CG1-CZ 3.46Å; V215-F219 VanDerWaalsContact CG1-CZ 3.46Å; V215-F219 VanDerWaalsContact O-CD2 3.26Å; V215-F219 WeakPolarHBondContact O-CD2 3.44Å; V215-F219 VanDerWaalsContact O-CG 3.28Å; V215-F219 WeakPolarHBondContact O-CG 3.12Å; V215-F219 PolarHBondContact O-N 3.15Å; V215-F356 HydrophobicContact CG1-CE1 4.5Å
216	Q	67.2	Low	74.3	Confident	63 Å²	63	66.4 Å²	66.4	29%	0.294	34%	0.341	S	S	.	.	H	α-helix	trans	-63.8	-41.8	177.2	-178.3	173.3	-32.9	0	0	113.4	A212 T213 R214 F218 F219 A220 N360	A212-Q216 WeakPolarHBondContact O-CB 3.42Å; A212-Q216 PolarHBondContact O-N 3.46Å; A212-Q216 VanDerWaalsContact O-N 3.16Å; T213-Q216 WeakPolarHBondContact O-CB 3.39Å; T213-Q216 PolarHBondContact O-N 2.86Å; R214-Q216 VanDerWaalsContact C-N 3.32Å; Q216-F218 VanDerWaalsContact C-N 3.33Å; Q216-F218 PolarHBondContact O-N 3.16Å; Q216-F219 PolarHBondContact O-N 3.42Å; Q216-A220 PolarHBondContact O-N 3.18Å; Q216-N360 PolarHBondContact OE1-ND2 3.4Å
217	D	68.4	Low	74.4	Confident	118 Å²	118	65.9 Å²	65.9	63%	0.631	34%	0.337	S	S	*	.	H	α-helix	trans	-61.5	-42.1	-179.8	-70.9	-18.8	0	0	0	111.9	T213 A220 A221	T213-D217 PolarHBondContact O-N 3.31Å; T213-D217 VanDerWaalsContact O-N 3.16Å; D217-A220 PolarHBondContact O-N 3.31Å; D217-A221 PolarHBondContact O-N 3.35Å
218	F	73.8	Confident	74.4	Confident	136 Å²	136	60.4 Å²	60.4	60%	0.596	32%	0.324	S	S	*	.	H	α-helix	trans	-62.6	-43.1	175.6	176.4	-103	0	0	0	111.8	R214 Q216 A220 A221 A222 L353	R214-F218 PolarHBondContact O-N 3.06Å; Q216-F218 VanDerWaalsContact C-N 3.33Å; Q216-F218 PolarHBondContact O-N 3.16Å; F218-A220 VanDerWaalsContact C-N 3.34Å; F218-A220 PolarHBondContact O-N 3.44Å; F218-A221 PolarHBondContact O-N 2.87Å; F218-A222 PolarHBondContact O-N 3.19Å; F218-A222 VanDerWaalsContact O-N 3.14Å; F218-L353 HydrophobicContact CE1-CD1 4.43Å
219	F	72.4	Confident	74.8	Confident	25 Å²	25	61.4 Å²	61.4	11%	0.11	33%	0.326	C	S	.	.	H	α-helix	trans	-68.9	-31	179	-61.1	-24.9	0	0	0	113.4	V215 Q216 A221 A222 K223 L353 F356	V215-F219 HydrophobicContact CB-CE2 4.42Å; V215-F219 HydrophobicContact CG1-CD2 3.76Å; V215-F219 HydrophobicContact CG1-CE1 4.45Å; V215-F219 HydrophobicContact CG1-CE2 3.04Å; V215-F219 HydrophobicContact CG1-CZ 3.46Å; V215-F219 VanDerWaalsContact CG1-CZ 3.46Å; V215-F219 VanDerWaalsContact O-CD2 3.26Å; V215-F219 WeakPolarHBondContact O-CD2 3.44Å; V215-F219 VanDerWaalsContact O-CG 3.28Å; V215-F219 WeakPolarHBondContact O-CG 3.12Å; V215-F219 PolarHBondContact O-N 3.15Å; Q216-F219 PolarHBondContact O-N 3.42Å; F219-A221 VanDerWaalsContact C-N 3.3Å; F219-A221 PolarHBondContact O-N 2.76Å; F219-A222 PolarHBondContact O-N 3.1Å; F219-K223 PolarHBondContact O-N 3.47Å; F219-K223 VanDerWaalsContact O-N 3.16Å; F219-L353 HydrophobicContact CD1-CB 3.8Å; F219-L353 HydrophobicContact CD1-CD1 3.98Å; F219-L353 HydrophobicContact CD1-CD2 3.91Å; F219-L353 HydrophobicContact CD1-CG 4.09Å; F219-L353 HydrophobicContact CE1-CB 4.2Å; F219-L353 HydrophobicContact CE1-CD1 3.97Å; F219-L353 HydrophobicContact CE1-CD2 3.39Å; F219-L353 HydrophobicContact CE1-CG 4.02Å; F219-L353 HydrophobicContact CE2-CD2 4.5Å; F219-L353 HydrophobicContact CG-CB 4.22Å; F219-L353 HydrophobicContact CZ-CD2 3.72Å; F219-F356 HydrophobicContact CD2-CD1 4.12Å; F219-F356 AromaticContact CE2-CD1 3.48Å; F219-F356 HydrophobicContact CE2-CD1 3.48Å; F219-F356 VanDerWaalsContact CE2-CD1 3.48Å; F219-F356 AromaticContact CE2-CE1 3.95Å; F219-F356 HydrophobicContact CE2-CE1 3.95Å; F219-F356 HydrophobicContact CE2-CG 4.44Å; F219-F356 HydrophobicContact CZ-CD1 4.38Å
220	A	70.8	Confident	75.8	Confident	35 Å²	35	59.6 Å²	59.6	29%	0.289	32%	0.316	S	S	.	.	H	α-helix	trans	-65.6	-32	174.7	0	0	0	0	0	112.8	Q216 D217 F218 K223	Q216-A220 PolarHBondContact O-N 3.18Å; D217-A220 PolarHBondContact O-N 3.31Å; F218-A220 VanDerWaalsContact C-N 3.34Å; F218-A220 PolarHBondContact O-N 3.44Å; A220-K223 VanDerWaalsContact O-CG 3.25Å; A220-K223 WeakPolarHBondContact O-CG 3.31Å
221	A	74.9	Confident	76.8	Confident	55 Å²	55	53.4 Å²	53.4	46%	0.455	29%	0.289	S	S	.	.	H	α-helix	trans	-74.7	-43	172.6	0	0	0	0	0	111.7	D217 F218 F219 K223 L224 L225	D217-A221 PolarHBondContact O-N 3.35Å; F218-A221 PolarHBondContact O-N 2.87Å; F219-A221 VanDerWaalsContact C-N 3.3Å; F219-A221 PolarHBondContact O-N 2.76Å; A221-K223 VanDerWaalsContact C-N 3.33Å; A221-K223 PolarHBondContact O-N 3.01Å; A221-L224 PolarHBondContact O-N 2.73Å; A221-L225 PolarHBondContact O-N 2.98Å
222	A	76	Confident	77.8	Confident	6 Å²	6	56.3 Å²	56.3	5%	0.05	30%	0.298	C	S	.	.	H	α-helix	trans	-58.8	-40.4	-178.2	0	0	0	0	0	113	F218 F219 L224 L225 A226 F350	F218-A222 PolarHBondContact O-N 3.19Å; F218-A222 VanDerWaalsContact O-N 3.14Å; F219-A222 PolarHBondContact O-N 3.1Å; A222-L224 PolarHBondContact O-N 3.25Å; A222-L225 PolarHBondContact O-N 2.85Å; A222-A226 PolarHBondContact O-N 3.36Å; A222-A226 VanDerWaalsContact O-N 3.1Å; A222-F350 HydrophobicContact CB-CD1 4Å; A222-F350 HydrophobicContact CB-CE1 4.32Å
223	K	77.1	Confident	78.9	Confident	12 Å²	12	57.5 Å²	57.5	5%	0.052	30%	0.304	C	S	.	.	H	α-helix	trans	-66.6	-35.2	178.7	69.8	-176.4	-176.4	-174.3	0	113.7	G80 I83 F219 A220 A221 L225 A226 L227	G80-K223 PolarHBondContact O-NZ 3.4Å; I83-K223 VanDerWaalsContact O-CD 3.32Å; I83-K223 WeakPolarHBondContact O-CD 3.28Å; I83-K223 WeakPolarHBondContact O-CE 3.28Å; I83-K223 PolarHBondContact O-NZ 3.37Å; F219-K223 PolarHBondContact O-N 3.47Å; F219-K223 VanDerWaalsContact O-N 3.16Å; A220-K223 VanDerWaalsContact O-CG 3.25Å; A220-K223 WeakPolarHBondContact O-CG 3.31Å; A221-K223 VanDerWaalsContact C-N 3.33Å; A221-K223 PolarHBondContact O-N 3.01Å; K223-L225 VanDerWaalsContact C-N 3.31Å; K223-A226 PolarHBondContact O-N 3.23Å; K223-L227 PolarHBondContact O-N 3.42Å; K223-L227 VanDerWaalsContact O-N 3.11Å
224	L	81.5	Confident	79.8	Confident	82 Å²	82	55 Å²	55	43%	0.429	29%	0.288	S	S	.	.	H	α-helix	trans	-69.1	-36.1	178.6	-68.7	177.1	0	0	0	110.4	I83 A221 A222 A228	I83-L224 HydrophobicContact CD1-CD2 4.02Å; A221-L224 PolarHBondContact O-N 2.73Å; A222-L224 PolarHBondContact O-N 3.25Å; L224-A228 VanDerWaalsContact O-CB 3.3Å; L224-A228 WeakPolarHBondContact O-CB 3.37Å; L224-A228 PolarHBondContact O-N 3.45Å
225	L	82.2	Confident	80.7	Confident	112 Å²	112	51 Å²	51	59%	0.586	28%	0.277	S	S	*	.	H	α-helix	trans	-64.1	-42.1	173	-68.1	173.4	0	0	0	112	A221 A222 K223 A228 L229	A221-L225 PolarHBondContact O-N 2.98Å; A222-L225 PolarHBondContact O-N 2.85Å; K223-L225 VanDerWaalsContact C-N 3.31Å; L225-A228 PolarHBondContact O-N 2.9Å; L225-L229 WeakPolarHBondContact O-CB 3.24Å; L225-L229 PolarHBondContact O-N 3.44Å
226	A	81.4	Confident	81.7	Confident	1 Å²	1	51.8 Å²	51.8	1%	0.008	28%	0.281	C	S	.	.	H	α-helix	trans	-62	-45.7	177.6	0	0	0	0	0	112.5	A222 K223 L229 I230 F350	A222-A226 PolarHBondContact O-N 3.36Å; A222-A226 VanDerWaalsContact O-N 3.1Å; K223-A226 PolarHBondContact O-N 3.23Å; A226-L229 WeakPolarHBondContact O-CB 3.42Å; A226-L229 PolarHBondContact O-N 2.74Å; A226-I230 WeakPolarHBondContact O-CG1 3.49Å; A226-I230 PolarHBondContact O-N 2.74Å; A226-I230 VanDerWaalsContact O-N 3.09Å; A226-F350 HydrophobicContact CB-CB 3.62Å; A226-F350 HydrophobicContact CB-CD2 3.9Å; A226-F350 HydrophobicContact CB-CG 4.14Å
227	L	87.3	Confident	82.5	Confident	3 Å²	3	52 Å²	52	2%	0.016	28%	0.281	C	S	.	.	H	α-helix	trans	-66.6	-40.3	176.7	-70.7	172.5	0	0	0	112.1	I83 I87 F88 K223 L229 I230 I231 V308 T312	I83-L227 HydrophobicContact CG2-CD1 3.26Å; I87-L227 HydrophobicContact CG1-CD2 4.44Å; I87-L227 HydrophobicContact CG2-CD2 4.14Å; F88-L227 HydrophobicContact CE1-CD2 3.99Å; F88-L227 HydrophobicContact CZ-CD2 3.92Å; F88-L227 HydrophobicContact CZ-CG 4.26Å; K223-L227 PolarHBondContact O-N 3.42Å; K223-L227 VanDerWaalsContact O-N 3.11Å; L227-L229 VanDerWaalsContact C-N 3.29Å; L227-L229 PolarHBondContact O-N 3.08Å; L227-I230 PolarHBondContact O-N 3.18Å; L227-I231 WeakPolarHBondContact O-CB 3.42Å; L227-I231 VanDerWaalsContact O-CG1 3.28Å; L227-I231 WeakPolarHBondContact O-CG1 3.23Å; L227-I231 PolarHBondContact O-N 2.72Å; L227-V308 HydrophobicContact CB-CG1 4.45Å; L227-V308 HydrophobicContact CD1-CG1 3.99Å; L227-T312 HydrophobicContact CD2-CG2 3.88Å
228	A	88.3	Confident	83.2	Confident	42 Å²	42	49.5 Å²	49.5	35%	0.347	27%	0.267	S	S	.	.	H	α-helix	trans	-59.3	-42.2	174.5	0	0	0	0	0	111.5	L224 L225 I231 I232	L224-A228 VanDerWaalsContact O-CB 3.3Å; L224-A228 WeakPolarHBondContact O-CB 3.37Å; L224-A228 PolarHBondContact O-N 3.45Å; L225-A228 PolarHBondContact O-N 2.9Å; A228-I231 PolarHBondContact O-N 3.31Å; A228-I232 WeakPolarHBondContact O-CB 3.48Å; A228-I232 WeakPolarHBondContact O-CD1 3.37Å; A228-I232 WeakPolarHBondContact O-CG1 3.44Å; A228-I232 PolarHBondContact O-N 2.98Å
229	L	87.5	Confident	83.6	Confident	55 Å²	55	46.3 Å²	46.3	29%	0.288	27%	0.273	S	S	.	.	H	α-helix	trans	-61.1	-47.6	176.7	-174.6	70.4	0	0	0	111.8	L225 A226 L227 I231 I232 I233 L340 I347	L225-L229 WeakPolarHBondContact O-CB 3.24Å; L225-L229 PolarHBondContact O-N 3.44Å; A226-L229 WeakPolarHBondContact O-CB 3.42Å; A226-L229 PolarHBondContact O-N 2.74Å; L227-L229 VanDerWaalsContact C-N 3.29Å; L227-L229 PolarHBondContact O-N 3.08Å; L229-I231 PolarHBondContact O-N 3.35Å; L229-I232 PolarHBondContact O-N 2.58Å; L229-I233 HydrophobicContact CD1-CD1 4.07Å; L229-I233 HydrophobicContact CG-CD1 3.9Å; L229-I233 VanDerWaalsContact O-CG1 3.29Å; L229-I233 WeakPolarHBondContact O-CG1 3.34Å; L229-I233 PolarHBondContact O-N 3.06Å; L229-L340 HydrophobicContact CD2-CD1 4.2Å; L229-L340 HydrophobicContact CD2-CD2 4.46Å; L229-I347 HydrophobicContact CD2-CD1 4.1Å
230	I	89.3	Confident	84	Confident	1 Å²	1	51 Å²	51	1%	0.005	30%	0.295	C	S	.	.	H	α-helix	trans	-59.4	-47.9	178.2	-67.6	166.8	0	0	0	110.6	F88 A226 L227 I233 G234 T312 A315 Y316 A332 F335 I347	F88-I230 HydrophobicContact CE1-CD1 4.26Å; A226-I230 WeakPolarHBondContact O-CG1 3.49Å; A226-I230 PolarHBondContact O-N 2.74Å; A226-I230 VanDerWaalsContact O-N 3.09Å; L227-I230 PolarHBondContact O-N 3.18Å; I230-I233 PolarHBondContact O-N 2.92Å; I230-G234 PolarHBondContact O-N 3.19Å; I230-T312 HydrophobicContact CG2-CG2 4.08Å; I230-A315 HydrophobicContact CG2-CB 3.92Å; I230-Y316 HydrophobicContact CD1-CE1 4.24Å; I230-Y316 HydrophobicContact CG2-CD1 4.31Å; I230-Y316 HydrophobicContact CG2-CE1 3.86Å; I230-A332 HydrophobicContact CD1-CB 4.35Å; I230-F335 HydrophobicContact CB-CE1 4.24Å; I230-F335 HydrophobicContact CG1-CD1 4.13Å; I230-F335 HydrophobicContact CG1-CE1 4.19Å; I230-F335 HydrophobicContact CG2-CD1 4.29Å; I230-F335 HydrophobicContact CG2-CE1 4.02Å; I230-F335 HydrophobicContact CG2-CZ 4.16Å; I230-I347 HydrophobicContact CG1-CD1 4.42Å
231	I	92.2	Very high	83.8	Confident	23 Å²	23	53.3 Å²	53.3	12%	0.118	31%	0.314	C	S	.	.	H	α-helix	trans	-62.7	-46.5	-179.3	-68.2	169.1	0	0	0	111.1	L227 A228 L229 I233 G234 F235 V308 L311	L227-I231 WeakPolarHBondContact O-CB 3.42Å; L227-I231 VanDerWaalsContact O-CG1 3.28Å; L227-I231 WeakPolarHBondContact O-CG1 3.23Å; L227-I231 PolarHBondContact O-N 2.72Å; A228-I231 PolarHBondContact O-N 3.31Å; L229-I231 PolarHBondContact O-N 3.35Å; I231-I233 PolarHBondContact O-N 3.3Å; I231-G234 PolarHBondContact O-N 3.2Å; I231-F235 HydrophobicContact CG2-CD2 3.69Å; I231-F235 HydrophobicContact CG2-CE2 3.6Å; I231-F235 VanDerWaalsContact O-CD2 3.28Å; I231-F235 WeakPolarHBondContact O-CD2 3.5Å; I231-F235 PolarHBondContact O-N 3.47Å; I231-V308 HydrophobicContact CD1-CG1 4.2Å; I231-L311 HydrophobicContact CD1-CB 4.03Å; I231-L311 HydrophobicContact CG1-CB 4.06Å; I231-L311 HydrophobicContact CG2-CB 4.23Å; I231-L311 HydrophobicContact CG2-CD1 4.41Å
232	I	91.2	Very high	83.1	Confident	105 Å²	105	52.2 Å²	52.2	54%	0.538	31%	0.308	S	S	.	.	H	α-helix	trans	-61.5	-46.2	-180	-69.5	164.8	0	0	0	110.7	A228 L229 G234 F235 V236	A228-I232 WeakPolarHBondContact O-CB 3.48Å; A228-I232 WeakPolarHBondContact O-CD1 3.37Å; A228-I232 WeakPolarHBondContact O-CG1 3.44Å; A228-I232 PolarHBondContact O-N 2.98Å; L229-I232 PolarHBondContact O-N 2.58Å; I232-G234 VanDerWaalsContact C-N 3.33Å; I232-G234 PolarHBondContact O-N 3.03Å; I232-F235 PolarHBondContact O-N 3.32Å; I232-V236 WeakPolarHBondContact O-CG2 3.22Å; I232-V236 PolarHBondContact O-N 2.81Å
233	I	88.3	Confident	82.6	Confident	29 Å²	29	54.1 Å²	54.1	15%	0.149	33%	0.328	C	S	.	.	H	α-helix	trans	-62.2	-42.9	178.1	-67.7	170.2	0	0	0	110.5	L229 I230 I231 F235 V236 K237 F335 H339 L340	L229-I233 HydrophobicContact CD1-CD1 4.07Å; L229-I233 HydrophobicContact CG-CD1 3.9Å; L229-I233 VanDerWaalsContact O-CG1 3.29Å; L229-I233 WeakPolarHBondContact O-CG1 3.34Å; L229-I233 PolarHBondContact O-N 3.06Å; I230-I233 PolarHBondContact O-N 2.92Å; I231-I233 PolarHBondContact O-N 3.3Å; I233-F235 PolarHBondContact O-N 3.34Å; I233-V236 PolarHBondContact O-N 3.06Å; I233-K237 PolarHBondContact O-N 2.86Å; I233-F335 HydrophobicContact CB-CE1 4Å; I233-F335 HydrophobicContact CB-CZ 3.88Å; I233-F335 HydrophobicContact CD1-CE1 4.29Å; I233-F335 HydrophobicContact CG2-CE1 3.87Å; I233-F335 HydrophobicContact CG2-CZ 3.59Å; I233-H339 HydrophobicContact CG2-CB 4.13Å; I233-H339 WeakPolarHBondContact CG2-CD2 2.97Å; I233-H339 WeakPolarHBondContact CG2-NE2 3.27Å; I233-L340 HydrophobicContact CD1-CD2 3.99Å; I233-L340 HydrophobicContact CD1-CG 4.48Å
234	G	87.8	Confident	82.4	Confident	1 Å²	1	55.1 Å²	55.1	1%	0.01	34%	0.335	C	S	.	.	H	α-helix	trans	-56.8	-45.8	175.4	0	0	0	0	0	112.8	I230 I231 I232 K237 I238	I230-G234 PolarHBondContact O-N 3.19Å; I231-G234 PolarHBondContact O-N 3.2Å; I232-G234 VanDerWaalsContact C-N 3.33Å; I232-G234 PolarHBondContact O-N 3.03Å; G234-K237 PolarHBondContact O-N 3.37Å; G234-I238 WeakPolarHBondContact O-CG1 3.21Å; G234-I238 PolarHBondContact O-N 3.5Å
235	F	88.9	Confident	81.9	Confident	108 Å²	108	56.2 Å²	56.2	47%	0.474	34%	0.342	S	S	.	.	H	α-helix	trans	-65	-38.6	176	-85.5	-68.6	0	0	0	113.3	I231 I232 I233 K237 I238 G239 L311	I231-F235 HydrophobicContact CG2-CD2 3.69Å; I231-F235 HydrophobicContact CG2-CE2 3.6Å; I231-F235 VanDerWaalsContact O-CD2 3.28Å; I231-F235 WeakPolarHBondContact O-CD2 3.5Å; I231-F235 PolarHBondContact O-N 3.47Å; I232-F235 PolarHBondContact O-N 3.32Å; I233-F235 PolarHBondContact O-N 3.34Å; F235-K237 VanDerWaalsContact C-N 3.29Å; F235-K237 PolarHBondContact O-N 3.34Å; F235-I238 HydrophobicContact CD1-CD1 4.46Å; F235-I238 PolarHBondContact O-N 3.4Å; F235-G239 PolarHBondContact O-N 2.89Å; F235-L311 HydrophobicContact CE2-CD1 4.42Å; F235-L311 HydrophobicContact CE2-CD2 3.93Å; F235-L311 HydrophobicContact CZ-CD2 3.63Å
236	V	88.4	Confident	81.4	Confident	75 Å²	75	54.8 Å²	54.8	46%	0.455	33%	0.332	S	S	.	.	H	α-helix	trans	-61.4	-40.5	174.8	171	0	0	0	0	110.7	I232 I233 G239 Q240	I232-V236 WeakPolarHBondContact O-CG2 3.22Å; I232-V236 PolarHBondContact O-N 2.81Å; I233-V236 PolarHBondContact O-N 3.06Å; V236-G239 PolarHBondContact O-N 3.12Å; V236-Q240 WeakPolarHBondContact O-CG 3.36Å; V236-Q240 PolarHBondContact O-N 2.84Å
237	K	83.9	Confident	81.2	Confident	68 Å²	68	56.5 Å²	56.5	30%	0.296	34%	0.341	S	S	.	.	H	α-helix	trans	-65.1	-42.1	176.6	-75.5	-62.8	-172	-178.4	0	113.5	I233 G234 F235 G239 Q240 A241 G242 H339	I233-K237 PolarHBondContact O-N 2.86Å; G234-K237 PolarHBondContact O-N 3.37Å; F235-K237 VanDerWaalsContact C-N 3.29Å; F235-K237 PolarHBondContact O-N 3.34Å; K237-G239 VanDerWaalsContact C-N 3.27Å; K237-G239 PolarHBondContact O-N 2.9Å; K237-Q240 PolarHBondContact O-N 3.26Å; K237-Q240 VanDerWaalsContact O-N 3.1Å; K237-A241 PolarHBondContact O-N 3.43Å; K237-G242 PolarHBondContact O-N 3.05Å; K237-H339 WeakPolarHBondContact CE-CD2 3.18Å; K237-H339 WeakPolarHBondContact CE-NE2 3.48Å; K237-H339 VanDerWaalsContact CG-NE2 3.35Å; K237-H339 WeakPolarHBondContact CG-NE2 3.08Å
238	I	84.9	Confident	80.8	Confident	65 Å²	65	59.9 Å²	59.9	33%	0.333	36%	0.359	S	S	.	.	H	α-helix	trans	-57.5	-44.5	172.1	-65.6	168.2	0	0	0	110.1	G234 F235 Q240 A241 T244 L314 T318	G234-I238 WeakPolarHBondContact O-CG1 3.21Å; G234-I238 PolarHBondContact O-N 3.5Å; F235-I238 HydrophobicContact CD1-CD1 4.46Å; F235-I238 PolarHBondContact O-N 3.4Å; I238-Q240 VanDerWaalsContact C-N 3.26Å; I238-Q240 PolarHBondContact O-N 2.86Å; I238-A241 PolarHBondContact O-N 3.25Å; I238-T244 HydrophobicContact CG1-CG2 4.26Å; I238-L314 HydrophobicContact CD1-CD2 4.26Å; I238-L314 HydrophobicContact CD1-CG 4.41Å; I238-T318 HydrophobicContact CD1-CG2 3.82Å; I238-T318 HydrophobicContact CG1-CG2 3.46Å; I238-T318 VanDerWaalsContact CG1-CG2 3.46Å
239	G	81.2	Confident	80.1	Confident	70 Å²	70	63.1 Å²	63.1	72%	0.722	38%	0.376	S	S	*	.	H	α-helix	trans	-66.8	-22	177.9	0	0	0	0	0	114.8	F235 V236 K237 A241	F235-G239 PolarHBondContact O-N 2.89Å; V236-G239 PolarHBondContact O-N 3.12Å; K237-G239 VanDerWaalsContact C-N 3.27Å; K237-G239 PolarHBondContact O-N 2.9Å; G239-A241 VanDerWaalsContact C-N 3.33Å
240	Q	81.9	Confident	79.6	Confident	122 Å²	122	68.2 Å²	68.2	57%	0.57	40%	0.399	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.5	3.6	176.3	-71.3	173.9	-0.8	0	0	113.2	V236 K237 I238 G242	V236-Q240 WeakPolarHBondContact O-CG 3.36Å; V236-Q240 PolarHBondContact O-N 2.84Å; K237-Q240 PolarHBondContact O-N 3.26Å; K237-Q240 VanDerWaalsContact O-N 3.1Å; I238-Q240 VanDerWaalsContact C-N 3.26Å; I238-Q240 PolarHBondContact O-N 2.86Å; Q240-G242 PolarHBondContact O-N 3.47Å
241	A	65.5	Low	79.3	Confident	85 Å²	85	70 Å²	70	70%	0.702	41%	0.408	S	S	*	.	T	Hydrogen-bonded Turn	trans	55	25	-176.4	0	0	0	0	0	114.6	K237 I238 G239	K237-A241 PolarHBondContact O-N 3.43Å; I238-A241 PolarHBondContact O-N 3.25Å; G239-A241 VanDerWaalsContact C-N 3.33Å
242	G	61.3	Low	78.9	Confident	32 Å²	32	69.4 Å²	69.4	33%	0.33	41%	0.406	S	S	.	.			trans	-98.2	135	176.7	0	0	0	0	0	111.7	K237 Q240 T244	K237-G242 PolarHBondContact O-N 3.05Å; Q240-G242 PolarHBondContact O-N 3.47Å; G242-T244 VanDerWaalsContact C-N 3.33Å; G242-T244 PolarHBondContact O-N 3.33Å
243	G	63.9	Low	78.7	Confident	45 Å²	45	68.9 Å²	68.9	46%	0.464	40%	0.4	S	S	.	.	S	Bend	trans	71.4	17.3	165	0	0	0	0	0	116.2
244	T	72.6	Confident	78.5	Confident	33 Å²	33	74 Å²	74	20%	0.202	42%	0.421	C	S	.	.			trans	-92.6	2.7	-179.9	52.7	0	0	0	0	114.2	I238 G242 E246 L247 L248	I238-T244 HydrophobicContact CG1-CG2 4.26Å; G242-T244 VanDerWaalsContact C-N 3.33Å; G242-T244 PolarHBondContact O-N 3.33Å; T244-E246 VanDerWaalsContact C-N 3.29Å; T244-E246 PolarHBondContact O-N 2.97Å; T244-L247 HydrophobicContact CG2-CD1 4.45Å; T244-L247 CarbonylContact O-C 3.58Å; T244-L247 WeakPolarHBondContact O-CA 3.5Å; T244-L247 WeakPolarHBondContact O-CB 3.49Å; T244-L247 PolarHBondContact O-N 3.18Å; T244-L248 PolarHBondContact O-N 2.92Å
245	D	72.8	Confident	78.2	Confident	105 Å²	105	76.9 Å²	76.9	56%	0.561	45%	0.451	S	S	*	.	G	3₁₀ helix	trans	-62.4	-35.5	-173	-63.5	-30.9	0	0	0	112.8	L247 L248 N251	D245-L247 VanDerWaalsContact C-N 3.31Å; D245-L248 WeakPolarHBondContact O-CB 3.5Å; D245-L248 PolarHBondContact O-N 2.93Å; D245-N251 WeakPolarHBondContact O-CB 3.47Å; D245-N251 PolarHBondContact O-ND2 3.37Å
246	E	71.8	Confident	78.1	Confident	83 Å²	83	72.6 Å²	72.6	39%	0.388	43%	0.434	S	S	.	.	G	3₁₀ helix	trans	-71.7	-25.3	174	-66.5	-61.8	157.1	0	0	112.6	V101 T244 L248 S252 P322	V101-E246 HydrophobicContact CG2-CB 4.39Å; T244-E246 VanDerWaalsContact C-N 3.29Å; T244-E246 PolarHBondContact O-N 2.97Å; E246-L248 VanDerWaalsContact C-N 3.32Å; E246-S252 WeakPolarHBondContact O-CA 3.31Å; E246-S252 PolarHBondContact O-N 3.32Å; E246-S252 PolarHBondContact O-OG 2.93Å; E246-S252 VanDerWaalsContact O-OG 3.05Å; E246-P322 HydrophobicContact CG-CG 4.31Å
247	L	76.2	Confident	77.9	Confident	36 Å²	36	70.8 Å²	70.8	19%	0.188	43%	0.425	C	S	.	.	G	3₁₀ helix	trans	-84.9	-6.7	177.7	-66.6	167.8	0	0	0	113	V101 L105 T244 D245 S252 L314 F317 T318	V101-L247 HydrophobicContact CG1-CD2 3.64Å; L105-L247 HydrophobicContact CD1-CD2 4.41Å; T244-L247 HydrophobicContact CG2-CD1 4.45Å; T244-L247 CarbonylContact O-C 3.58Å; T244-L247 WeakPolarHBondContact O-CA 3.5Å; T244-L247 WeakPolarHBondContact O-CB 3.49Å; T244-L247 PolarHBondContact O-N 3.18Å; D245-L247 VanDerWaalsContact C-N 3.31Å; L247-S252 WeakPolarHBondContact CA-OG 3.31Å; L247-S252 PolarHBondContact O-OG 3.15Å; L247-S252 VanDerWaalsContact O-OG 3.11Å; L247-L314 HydrophobicContact CD1-CD1 3.79Å; L247-L314 HydrophobicContact CD2-CD1 3.58Å; L247-L314 HydrophobicContact CG-CD1 4.33Å; L247-F317 HydrophobicContact CD2-CB 4.07Å; L247-T318 HydrophobicContact CD1-CG2 3.41Å; L247-T318 VanDerWaalsContact CD1-CG2 3.41Å
248	L	79.9	Confident	78	Confident	75 Å²	75	74.6 Å²	74.6	39%	0.393	44%	0.438	S	S	.	.	S	Bend	trans	-67.7	141	173	-66.7	173.2	0	0	0	110	T244 D245 E246 E250 N251 S252	T244-L248 PolarHBondContact O-N 2.92Å; D245-L248 WeakPolarHBondContact O-CB 3.5Å; D245-L248 PolarHBondContact O-N 2.93Å; E246-L248 VanDerWaalsContact C-N 3.32Å; L248-E250 PolarHBondContact O-N 3.47Å; L248-N251 PolarHBondContact O-N 2.96Å; L248-S252 WeakPolarHBondContact O-CB 3.43Å; L248-S252 PolarHBondContact O-N 3.17Å; L248-S252 PolarHBondContact O-OG 3.4Å
249	P	73.1	Confident	78	Confident	110 Å²	110	77.3 Å²	77.3	71%	0.714	45%	0.45	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.9	-29.8	-179.2	-27.5	34.4	0	0	0	114.2	N251	P249-N251 VanDerWaalsContact C-N 3.34Å
250	E	76.6	Confident	78	Confident	162 Å²	162	81.6 Å²	81.6	76%	0.757	45%	0.449	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.9	-28.9	179.2	-59.9	-176.9	-179.1	0	0	113.5	L248 K254	L248-E250 PolarHBondContact O-N 3.47Å; E250-K254 VanDerWaalsContact O-CE 3.29Å; E250-K254 WeakPolarHBondContact O-CE 3.36Å
251	N	82.8	Confident	77.9	Confident	38 Å²	38	76.4 Å²	76.4	20%	0.203	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-110.2	-26.3	-176.8	-63.9	-34.1	0	0	0	113.2	D245 L248 P249 F253 K254	D245-N251 WeakPolarHBondContact O-CB 3.47Å; D245-N251 PolarHBondContact O-ND2 3.37Å; L248-N251 PolarHBondContact O-N 2.96Å; P249-N251 VanDerWaalsContact C-N 3.34Å; N251-F253 PolarHBondContact O-N 3.31Å; N251-K254 WeakPolarHBondContact O-CB 3.5Å; N251-K254 PolarHBondContact O-N 3.18Å; N251-K254 WeakPolarHBondContact OD1-CE 3.49Å; N251-K254 PolarHBondContact OD1-NZ 3.48Å
252	S	83	Confident	78.9	Confident	11 Å²	11	73.6 Å²	73.6	8%	0.077	40%	0.401	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.7	-27.7	-172.4	-68.8	0	0	0	0	115.1	S100 V101 G102 E246 L247 L248	S100-S252 WeakPolarHBondContact CB-O 3.27Å; V101-S252 PolarHBondContact N-O 3.45Å; G102-S252 WeakPolarHBondContact CA-O 2.96Å; G102-S252 PolarHBondContact N-O 3.44Å; E246-S252 WeakPolarHBondContact O-CA 3.31Å; E246-S252 PolarHBondContact O-N 3.32Å; E246-S252 PolarHBondContact O-OG 2.93Å; E246-S252 VanDerWaalsContact O-OG 3.05Å; L247-S252 WeakPolarHBondContact CA-OG 3.31Å; L247-S252 PolarHBondContact O-OG 3.15Å; L247-S252 VanDerWaalsContact O-OG 3.11Å; L248-S252 WeakPolarHBondContact O-CB 3.43Å; L248-S252 PolarHBondContact O-N 3.17Å; L248-S252 PolarHBondContact O-OG 3.4Å
253	F	87.8	Confident	80.1	Confident	94 Å²	94	74.3 Å²	74.3	41%	0.412	40%	0.397	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.7	3.9	-179.3	-66.1	-79.7	0	0	0	114.1	I106 N251 G255 S256	I106-F253 HydrophobicContact CD1-CE1 3.7Å; I106-F253 HydrophobicContact CD1-CZ 3.95Å; N251-F253 PolarHBondContact O-N 3.31Å; F253-G255 PolarHBondContact O-N 3.11Å; F253-S256 WeakPolarHBondContact CA-OG 3.36Å; F253-S256 WeakPolarHBondContact O-CB 3.46Å; F253-S256 PolarHBondContact O-N 3.02Å; F253-S256 PolarHBondContact O-OG 2.87Å
254	K	83.8	Confident	81.1	Confident	137 Å²	137	72.1 Å²	72.1	60%	0.596	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.3	135.5	175.5	-72.5	-178.2	177.3	167.3	0	109.8	S100 E250 N251 S256	S100-K254 VanDerWaalsContact CB-O 3.27Å; S100-K254 WeakPolarHBondContact CB-O 3.39Å; E250-K254 VanDerWaalsContact O-CE 3.29Å; E250-K254 WeakPolarHBondContact O-CE 3.36Å; N251-K254 WeakPolarHBondContact O-CB 3.5Å; N251-K254 PolarHBondContact O-N 3.18Å; N251-K254 WeakPolarHBondContact OD1-CE 3.49Å; N251-K254 PolarHBondContact OD1-NZ 3.48Å; K254-S256 VanDerWaalsContact C-N 3.3Å; K254-S256 PolarHBondContact O-N 3.29Å
255	G	82	Confident	81.6	Confident	61 Å²	61	71.4 Å²	71.4	63%	0.629	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	77	8.7	-178.5	0	0	0	0	0	115.6	G99 F253 S257	G99-G255 CarbonylContact C-O 3.48Å; F253-G255 PolarHBondContact O-N 3.11Å; G255-S257 PolarHBondContact O-N 2.9Å
256	S	86.9	Confident	82.4	Confident	18 Å²	18	66.4 Å²	66.4	13%	0.126	34%	0.343	C	S	.	.			trans	-59.1	124.9	-179.9	-61.7	0	0	0	0	112.1	S100 F253 K254 Y258	S100-S256 VanDerWaalsContact CB-OG 3.26Å; S100-S256 WeakPolarHBondContact CB-OG 3.46Å; S100-S256 PolarHBondContact OG-OG 3.39Å; F253-S256 WeakPolarHBondContact CA-OG 3.36Å; F253-S256 WeakPolarHBondContact O-CB 3.46Å; F253-S256 PolarHBondContact O-N 3.02Å; F253-S256 PolarHBondContact O-OG 2.87Å; K254-S256 VanDerWaalsContact C-N 3.3Å; K254-S256 PolarHBondContact O-N 3.29Å; S256-Y258 VanDerWaalsContact CB-CE2 3.45Å; S256-Y258 WeakPolarHBondContact CB-OH 3.5Å; S256-Y258 WeakPolarHBondContact O-CD2 3.46Å; S256-Y258 PolarHBondContact O-N 2.92Å; S256-Y258 PolarHBondContact OG-OH 3.38Å
257	S	84.9	Confident	83.2	Confident	37 Å²	37	63.7 Å²	63.7	26%	0.259	33%	0.331	S	S	.	.			trans	-86.9	102.5	173.3	-71.5	0	0	0	0	109.9	E97 A98 G255 E259	E97-S257 WeakPolarHBondContact O-CB 3.35Å; A98-S257 PolarHBondContact O-N 3.04Å; G255-S257 PolarHBondContact O-N 2.9Å; S257-E259 VanDerWaalsContact C-N 3.29Å
258	Y	84.8	Confident	83.6	Confident	147 Å²	147	62 Å²	62	58%	0.576	32%	0.322	S	S	*	.			trans	-88.8	7.8	178.3	-60.8	-73.2	0	0	0	113.9	S256 F260	S256-Y258 VanDerWaalsContact CB-CE2 3.45Å; S256-Y258 WeakPolarHBondContact CB-OH 3.5Å; S256-Y258 WeakPolarHBondContact O-CD2 3.46Å; S256-Y258 PolarHBondContact O-N 2.92Å; S256-Y258 PolarHBondContact OG-OH 3.38Å; Y258-F260 PolarHBondContact O-N 3.4Å
259	E	84.8	Confident	83.9	Confident	123 Å²	123	58.7 Å²	58.7	58%	0.575	31%	0.305	S	S	*	.			trans	-65.2	128.6	175.9	-68.3	-168.9	172.4	0	0	110.8	S257 G261 N262 I263	S257-E259 VanDerWaalsContact C-N 3.29Å; E259-G261 PolarHBondContact O-N 2.92Å; E259-N262 PolarHBondContact O-N 3.21Å; E259-I263 PolarHBondContact O-N 3.46Å; E259-I263 VanDerWaalsContact O-N 3.13Å
260	F	81.1	Confident	84.8	Confident	159 Å²	159	53.5 Å²	53.5	70%	0.697	27%	0.271	S	S	*	.	H	α-helix	trans	-51.2	-36.6	-179.1	-69.3	-78.7	0	0	0	113.4	Y258 G264	Y258-F260 PolarHBondContact O-N 3.4Å; F260-G264 PolarHBondContact O-N 3.49Å
261	G	81.1	Confident	85.4	Confident	14 Å²	14	46 Å²	46	14%	0.144	24%	0.236	C	C	.	.	H	α-helix	trans	-69.6	-42.1	-179.6	0	0	0	0	0	113.6	E259 G264 L265 K473	E259-G261 PolarHBondContact O-N 2.92Å; G261-G264 PolarHBondContact O-N 2.89Å; G261-L265 WeakPolarHBondContact O-CG 3.3Å; G261-L265 PolarHBondContact O-N 3.29Å; G261-L265 VanDerWaalsContact O-N 3.13Å; G261-K473 VanDerWaalsContact CA-CE 3.5Å
262	N	85.8	Confident	85.6	Confident	25 Å²	25	45.1 Å²	45.1	13%	0.134	23%	0.231	C	C	.	.	H	α-helix	trans	-73.1	-37.6	-178	-56.6	-6	0	0	0	110.1	E97 E259 G264 L265 A266 K473	E97-N262 HydrophobicContact CB-CB 4.5Å; E97-N262 WeakPolarHBondContact CB-O 3.31Å; E97-N262 WeakPolarHBondContact O-CB 3.43Å; E259-N262 PolarHBondContact O-N 3.21Å; N262-G264 VanDerWaalsContact C-N 3.28Å; N262-G264 PolarHBondContact O-N 3.38Å; N262-L265 PolarHBondContact O-N 2.93Å; N262-A266 WeakPolarHBondContact O-CB 3.3Å; N262-A266 PolarHBondContact O-N 2.88Å; N262-K473 PolarHBondContact OD1-NZ 2.88Å
263	I	86.7	Confident	86	Confident	47 Å²	47	44.7 Å²	44.7	24%	0.241	23%	0.228	C	C	.	.	H	α-helix	trans	-58.3	-41.5	171.7	-63.7	172.5	0	0	0	111	E259 A266 L267	E259-I263 PolarHBondContact O-N 3.46Å; E259-I263 VanDerWaalsContact O-N 3.13Å; I263-A266 PolarHBondContact O-N 3.42Å; I263-L267 HydrophobicContact CG2-CD1 4.09Å; I263-L267 HydrophobicContact CG2-CG 4.45Å; I263-L267 WeakPolarHBondContact O-CB 3.5Å; I263-L267 VanDerWaalsContact O-CG 3.27Å; I263-L267 WeakPolarHBondContact O-CG 3.37Å; I263-L267 PolarHBondContact O-N 2.83Å
264	G	84.4	Confident	86.1	Confident	0 Å²	0	40.2 Å²	40.2	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-63.1	-42.6	176.2	0	0	0	0	0	113.5	F260 G261 N262 L267 Y268	F260-G264 PolarHBondContact O-N 3.49Å; G261-G264 PolarHBondContact O-N 2.89Å; N262-G264 VanDerWaalsContact C-N 3.28Å; N262-G264 PolarHBondContact O-N 3.38Å; G264-L267 PolarHBondContact O-N 2.97Å; G264-Y268 WeakPolarHBondContact O-CD2 3.44Å; G264-Y268 PolarHBondContact O-N 2.94Å
265	L	83.6	Confident	86.2	Confident	18 Å²	18	35.2 Å²	35.2	9%	0.094	20%	0.196	C	C	.	.	H	α-helix	trans	-67.8	-38.4	175.9	-66.2	175.3	0	0	0	112.3	E97 G261 N262 L267 Y268 S269 K473	E97-L265 HydrophobicContact CB-CB 4.45Å; E97-L265 HydrophobicContact CG-CB 3.82Å; G261-L265 WeakPolarHBondContact O-CG 3.3Å; G261-L265 PolarHBondContact O-N 3.29Å; G261-L265 VanDerWaalsContact O-N 3.13Å; N262-L265 PolarHBondContact O-N 2.93Å; L265-L267 VanDerWaalsContact C-N 3.35Å; L265-Y268 HydrophobicContact CD2-CD2 4.28Å; L265-Y268 PolarHBondContact O-N 3.44Å; L265-S269 PolarHBondContact O-N 3.45Å; L265-S269 VanDerWaalsContact O-N 3.07Å; L265-S269 PolarHBondContact O-OG 2.91Å; L265-K473 HydrophobicContact CD1-CB 4.32Å; L265-K473 HydrophobicContact CD1-CD 4.16Å; L265-K473 HydrophobicContact CD1-CG 4.18Å; L265-K473 HydrophobicContact CD2-CB 4.4Å; L265-K473 HydrophobicContact CG-CG 4.48Å
266	A	89.3	Confident	86.1	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-60.8	-45.3	172.4	0	0	0	0	0	110.9	E97 V107 N262 I263 Y268 S269 G270	E97-A266 HydrophobicContact CB-CB 3.75Å; V107-A266 HydrophobicContact CG1-CB 4.19Å; V107-A266 HydrophobicContact CG2-CB 4.29Å; N262-A266 WeakPolarHBondContact O-CB 3.3Å; N262-A266 PolarHBondContact O-N 2.88Å; I263-A266 PolarHBondContact O-N 3.42Å; A266-Y268 VanDerWaalsContact C-N 3.31Å; A266-Y268 PolarHBondContact O-N 3.46Å; A266-S269 PolarHBondContact O-N 2.79Å; A266-G270 PolarHBondContact O-N 2.99Å
267	L	89.7	Confident	86.1	Confident	26 Å²	26	32 Å²	32	14%	0.136	16%	0.164	C	C	.	.	H	α-helix	trans	-60.9	-38.1	175.2	-75	168.7	0	0	0	111.5	V107 V110 I263 G264 L265 G270 L271 L466	V107-L267 HydrophobicContact CG1-CD2 4.2Å; V110-L267 HydrophobicContact CG1-CD2 4.02Å; I263-L267 HydrophobicContact CG2-CD1 4.09Å; I263-L267 HydrophobicContact CG2-CG 4.45Å; I263-L267 WeakPolarHBondContact O-CB 3.5Å; I263-L267 VanDerWaalsContact O-CG 3.27Å; I263-L267 WeakPolarHBondContact O-CG 3.37Å; I263-L267 PolarHBondContact O-N 2.83Å; G264-L267 PolarHBondContact O-N 2.97Å; L265-L267 VanDerWaalsContact C-N 3.35Å; L267-G270 PolarHBondContact O-N 3.47Å; L267-L271 WeakPolarHBondContact O-CB 3.4Å; L267-L271 WeakPolarHBondContact O-CG 3.34Å; L267-L271 PolarHBondContact O-N 3.34Å; L267-L466 HydrophobicContact CB-CD2 3.88Å; L267-L466 HydrophobicContact CD1-CD2 4.14Å
268	Y	84.3	Confident	86	Confident	0 Å²	0	31 Å²	31	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-63.6	-46	174.8	-74.9	-40.5	0	0	0	113.5	G264 L265 A266 G270 L271 F272 W425 L466 I467 S470	G264-Y268 WeakPolarHBondContact O-CD2 3.44Å; G264-Y268 PolarHBondContact O-N 2.94Å; L265-Y268 HydrophobicContact CD2-CD2 4.28Å; L265-Y268 PolarHBondContact O-N 3.44Å; A266-Y268 VanDerWaalsContact C-N 3.31Å; A266-Y268 PolarHBondContact O-N 3.46Å; Y268-G270 VanDerWaalsContact C-N 3.32Å; Y268-G270 PolarHBondContact O-N 3.32Å; Y268-L271 PolarHBondContact O-N 2.88Å; Y268-F272 WeakPolarHBondContact O-CB 3.31Å; Y268-F272 PolarHBondContact O-N 2.85Å; Y268-W425 AromaticContact CD1-CD1 3.85Å; Y268-W425 AromaticContact CD1-NE1 3.96Å; Y268-W425 AromaticContact CE1-CD1 3.51Å; Y268-W425 HydrophobicContact CE1-CG 4.41Å; Y268-L466 HydrophobicContact CD1-CD2 4.28Å; Y268-L466 HydrophobicContact CE1-CB 3.65Å; Y268-L466 HydrophobicContact CE1-CD1 4.11Å; Y268-L466 HydrophobicContact CE1-CD2 4.01Å; Y268-L466 HydrophobicContact CE1-CG 4.13Å; Y268-L466 PolarHBondContact OH-O 3.27Å; Y268-I467 PolarHBondContact OH-N 3.46Å; Y268-S470 WeakPolarHBondContact CE2-OG 3.19Å; Y268-S470 PolarHBondContact OH-OG 3.4Å
269	S	86.1	Confident	85.4	Confident	6 Å²	6	26.4 Å²	26.4	4%	0.042	14%	0.138	C	C	.	.	H	α-helix	trans	-58.3	-47.8	175.5	-65.1	0	0	0	0	110.4	T90 L265 A266	T90-S269 WeakPolarHBondContact CB-O 3.42Å; T90-S269 WeakPolarHBondContact CG2-O 3.35Å; L265-S269 PolarHBondContact O-N 3.45Å; L265-S269 VanDerWaalsContact O-N 3.07Å; L265-S269 PolarHBondContact O-OG 2.91Å; A266-S269 PolarHBondContact O-N 2.79Å
270	G	90.9	Very high	84.8	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-61.9	-49.4	177	0	0	0	0	0	112.6	A266 L267 Y268 F272 A273 Y274	A266-G270 PolarHBondContact O-N 2.99Å; L267-G270 PolarHBondContact O-N 3.47Å; Y268-G270 VanDerWaalsContact C-N 3.32Å; Y268-G270 PolarHBondContact O-N 3.32Å; G270-F272 VanDerWaalsContact C-N 3.3Å; G270-F272 PolarHBondContact O-N 2.98Å; G270-A273 WeakPolarHBondContact O-CB 3.39Å; G270-A273 PolarHBondContact O-N 3.24Å; G270-Y274 VanDerWaalsContact O-CD2 3.3Å; G270-Y274 WeakPolarHBondContact O-CD2 3.08Å; G270-Y274 PolarHBondContact O-N 3.22Å
271	L	90.3	Very high	84.6	Confident	4 Å²	4	13.4 Å²	13.4	2%	0.021	8%	0.079	C	C	.	.	H	α-helix	trans	-66	-28.8	-177.2	-74.9	175.4	0	0	0	113.8	C111 F114 L267 Y268 A273 Y274 G275 W425 L466	C111-L271 HydrophobicContact CB-CD2 3.84Å; C111-L271 HydrophobicContact CB-CG 4.28Å; F114-L271 HydrophobicContact CD1-CD1 4.01Å; F114-L271 HydrophobicContact CD1-CD2 3.44Å; F114-L271 VanDerWaalsContact CD1-CD2 3.44Å; F114-L271 HydrophobicContact CD1-CG 4.39Å; F114-L271 HydrophobicContact CE1-CD1 3.88Å; F114-L271 HydrophobicContact CE1-CD2 4.03Å; F114-L271 HydrophobicContact CG-CD2 4.39Å; L267-L271 WeakPolarHBondContact O-CB 3.4Å; L267-L271 WeakPolarHBondContact O-CG 3.34Å; L267-L271 PolarHBondContact O-N 3.34Å; Y268-L271 PolarHBondContact O-N 2.88Å; L271-A273 VanDerWaalsContact C-N 3.29Å; L271-A273 PolarHBondContact O-N 3.45Å; L271-Y274 CarbonylContact O-C 3.57Å; L271-Y274 PolarHBondContact O-N 2.8Å; L271-G275 PolarHBondContact O-N 2.9Å; L271-G275 VanDerWaalsContact O-N 3.13Å; L271-W425 HydrophobicContact CB-CZ2 3.74Å; L271-W425 HydrophobicContact CD1-CH2 4.36Å; L271-W425 HydrophobicContact CD1-CZ2 3.76Å; L271-W425 HydrophobicContact CD2-CH2 4.35Å; L271-W425 HydrophobicContact CD2-CZ2 4.15Å; L271-W425 HydrophobicContact CG-CZ2 4.08Å; L271-L466 HydrophobicContact CD1-CD1 3.55Å
272	F	87.3	Confident	84.1	Confident	20 Å²	20	14.6 Å²	14.6	9%	0.088	8%	0.08	C	C	.	.	H	α-helix	trans	-58.2	-43.4	169.9	176.7	-97.2	0	0	0	111.1	T90 I166 Y268 G270 Y274 G275 I417 F420	T90-F272 HydrophobicContact CG2-CB 4.42Å; T90-F272 HydrophobicContact CG2-CD1 3.79Å; I166-F272 HydrophobicContact CB-CZ 4.24Å; I166-F272 HydrophobicContact CD1-CE2 3.94Å; I166-F272 HydrophobicContact CD1-CZ 4.19Å; I166-F272 HydrophobicContact CG2-CE1 3.99Å; I166-F272 HydrophobicContact CG2-CE2 4.37Å; I166-F272 HydrophobicContact CG2-CZ 3.55Å; Y268-F272 WeakPolarHBondContact O-CB 3.31Å; Y268-F272 PolarHBondContact O-N 2.85Å; G270-F272 VanDerWaalsContact C-N 3.3Å; G270-F272 PolarHBondContact O-N 2.98Å; F272-Y274 VanDerWaalsContact C-N 3.27Å; F272-Y274 PolarHBondContact O-N 3.49Å; F272-G275 PolarHBondContact O-N 3.07Å; F272-G275 VanDerWaalsContact O-N 3.07Å; F272-I417 HydrophobicContact CB-CG2 4.21Å; F272-I417 HydrophobicContact CD2-CG2 4.27Å; F272-I417 HydrophobicContact CG-CG2 4.19Å; F272-F420 AromaticContact CD2-CD1 3.71Å; F272-F420 HydrophobicContact CD2-CD1 3.71Å; F272-F420 AromaticContact CD2-CE1 3.63Å; F272-F420 HydrophobicContact CD2-CE1 3.63Å; F272-F420 AromaticContact CE2-CD1 3.99Å; F272-F420 HydrophobicContact CE2-CD1 3.99Å; F272-F420 AromaticContact CE2-CE1 3.95Å; F272-F420 HydrophobicContact CE2-CE1 3.95Å
273	A	90.1	Very high	83.3	Confident	2 Å²	2	14.4 Å²	14.4	2%	0.017	8%	0.08	C	C	.	.	H	α-helix	trans	-69.5	-23.4	178.1	0	0	0	0	0	113.6	T90 W108 G270 L271 Y309	T90-A273 HydrophobicContact CG2-CB 4.18Å; T90-A273 WeakPolarHBondContact OG1-CB 3.49Å; W108-A273 HydrophobicContact CH2-CB 3.6Å; W108-A273 HydrophobicContact CZ3-CB 3.73Å; G270-A273 WeakPolarHBondContact O-CB 3.39Å; G270-A273 PolarHBondContact O-N 3.24Å; L271-A273 VanDerWaalsContact C-N 3.29Å; L271-A273 PolarHBondContact O-N 3.45Å; A273-Y309 HydrophobicContact CB-CE2 4.02Å; A273-Y309 VanDerWaalsContact O-CE2 3.25Å; A273-Y309 WeakPolarHBondContact O-CE2 3.37Å; A273-Y309 PolarHBondContact O-OH 2.91Å
274	Y	90	Very high	82.7	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.071	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.1	-1.8	171.8	-73.4	-84.4	0	0	0	113.6	W108 C111 S115 G270 L271 F272 V305 T306 Y309	W108-Y274 HydrophobicContact CE3-CD2 4.47Å; W108-Y274 AromaticContact CE3-CE2 3.59Å; W108-Y274 HydrophobicContact CE3-CE2 3.59Å; W108-Y274 HydrophobicContact CZ3-CD2 4.42Å; W108-Y274 AromaticContact CZ3-CE2 3.92Å; W108-Y274 HydrophobicContact CZ3-CE2 3.92Å; W108-Y274 WeakPolarHBondContact O-CE2 3.47Å; W108-Y274 PolarHBondContact O-OH 3.34Å; C111-Y274 HydrophobicContact CB-CD2 3.52Å; C111-Y274 HydrophobicContact CB-CE2 3.43Å; C111-Y274 VanDerWaalsContact CB-CE2 3.43Å; S115-Y274 WeakPolarHBondContact OG-CB 3.23Å; G270-Y274 VanDerWaalsContact O-CD2 3.3Å; G270-Y274 WeakPolarHBondContact O-CD2 3.08Å; G270-Y274 PolarHBondContact O-N 3.22Å; L271-Y274 CarbonylContact O-C 3.57Å; L271-Y274 PolarHBondContact O-N 2.8Å; F272-Y274 VanDerWaalsContact C-N 3.27Å; F272-Y274 PolarHBondContact O-N 3.49Å; Y274-V305 HydrophobicContact CD1-CG1 3.99Å; Y274-V305 HydrophobicContact CE1-CG1 3.88Å; Y274-T306 WeakPolarHBondContact OH-CA 3.35Å; Y274-Y309 HydrophobicContact CD1-CD2 4.12Å; Y274-Y309 HydrophobicContact CD1-CE2 4.09Å; Y274-Y309 HydrophobicContact CD2-CD2 4.24Å; Y274-Y309 HydrophobicContact CD2-CE2 4.36Å; Y274-Y309 AromaticContact CE1-CD2 3.65Å; Y274-Y309 HydrophobicContact CE1-CD2 3.65Å; Y274-Y309 HydrophobicContact CE1-CE2 4.09Å; Y274-Y309 AromaticContact CE2-CD2 3.81Å; Y274-Y309 HydrophobicContact CE2-CD2 3.81Å; Y274-Y309 HydrophobicContact CE2-CE2 4.38Å; Y274-Y309 HydrophobicContact CG-CD2 4.4Å; Y274-Y309 HydrophobicContact CG-CE2 4.23Å; Y274-Y309 AromaticContact CZ-CD2 3.5Å; Y274-Y309 VanDerWaalsContact CZ-CD2 3.5Å
275	G	85.3	Confident	82.2	Confident	32 Å²	32	15.8 Å²	15.8	33%	0.33	9%	0.086	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.2	142	178.3	0	0	0	0	0	112.1	L271 F272	L271-G275 PolarHBondContact O-N 2.9Å; L271-G275 VanDerWaalsContact O-N 3.13Å; F272-G275 PolarHBondContact O-N 3.07Å; F272-G275 VanDerWaalsContact O-N 3.07Å
276	G	80.9	Confident	81.9	Confident	6 Å²	6	16.7 Å²	16.7	6%	0.062	9%	0.09	C	C	.	.	T	Hydrogen-bonded Turn	trans	121	-12.7	177.2	0	0	0	0	0	115.5	N278 Y279	G276-N278 VanDerWaalsContact C-N 3.26Å; G276-N278 PolarHBondContact O-N 3.45Å; G276-Y279 VanDerWaalsContact CA-CD2 3.48Å; G276-Y279 WeakPolarHBondContact O-CB 3.42Å; G276-Y279 VanDerWaalsContact O-CD2 3.26Å; G276-Y279 WeakPolarHBondContact O-CD2 3.3Å; G276-Y279 PolarHBondContact O-N 3.16Å; G276-Y279 VanDerWaalsContact O-N 3.15Å
277	W	86.6	Confident	81.5	Confident	6 Å²	6	16.7 Å²	16.7	2%	0.023	9%	0.09	C	C	.	.	G	3₁₀ helix	trans	-65.5	-26.4	-178.7	52.2	-103.3	0	0	0	113.8	I82 A119 Y122 Y279 L302 W425 I428 F459	I82-W277 HydrophobicContact CD1-CB 3.79Å; I82-W277 HydrophobicContact CG1-CB 4.49Å; A119-W277 VanDerWaalsContact CA-CE3 3.47Å; A119-W277 HydrophobicContact CB-CB 4.24Å; A119-W277 HydrophobicContact CB-CD2 4.11Å; A119-W277 HydrophobicContact CB-CE3 3.66Å; A119-W277 HydrophobicContact CB-CG 4.36Å; A119-W277 HydrophobicContact CB-CZ3 4.36Å; Y122-W277 HydrophobicContact CD1-CZ3 4.44Å; Y122-W277 AromaticContact CD2-CH2 3.71Å; Y122-W277 HydrophobicContact CD2-CH2 3.71Å; Y122-W277 AromaticContact CD2-CZ3 3.41Å; Y122-W277 HydrophobicContact CD2-CZ3 3.41Å; Y122-W277 VanDerWaalsContact CD2-CZ3 3.41Å; Y122-W277 AromaticContact CE2-CH2 3.84Å; Y122-W277 HydrophobicContact CE2-CH2 3.84Å; Y122-W277 AromaticContact CE2-CZ3 3.94Å; Y122-W277 HydrophobicContact CE2-CZ3 3.94Å; Y122-W277 HydrophobicContact CG-CH2 4.4Å; Y122-W277 AromaticContact CG-CZ3 3.67Å; Y122-W277 HydrophobicContact CG-CZ3 3.67Å; W277-Y279 PolarHBondContact O-N 3.09Å; W277-L302 HydrophobicContact CB-CD1 4.43Å; W277-L302 HydrophobicContact CB-CD2 4.12Å; W277-W425 HydrophobicContact CZ2-CH2 4.35Å; W277-W425 HydrophobicContact CZ2-CZ3 4.43Å; W277-I428 HydrophobicContact CH2-CD1 4.42Å; W277-I428 HydrophobicContact CH2-CG2 4.37Å; W277-I428 HydrophobicContact CZ2-CD1 4.15Å; W277-F459 HydrophobicContact CH2-CZ 4.3Å; W277-F459 HydrophobicContact CZ2-CZ 4.23Å
278	N	83.2	Confident	81.3	Confident	16 Å²	16	18.6 Å²	18.6	9%	0.086	10%	0.1	C	C	.	.	G	3₁₀ helix	trans	-72.8	-12.9	177.5	60.6	-34.5	0	0	0	112.8	Y122 D135 G276 L280 N281	Y122-N278 HydrophobicContact CD1-CB 4.23Å; Y122-N278 HydrophobicContact CE1-CB 4.21Å; D135-N278 PolarHBondContact OD2-ND2 3.4Å; G276-N278 VanDerWaalsContact C-N 3.26Å; G276-N278 PolarHBondContact O-N 3.45Å; N278-L280 VanDerWaalsContact C-N 3.34Å; N278-L280 PolarHBondContact O-N 3.38Å; N278-N281 WeakPolarHBondContact O-CB 3.46Å; N278-N281 PolarHBondContact O-N 2.82Å; N278-N281 PolarHBondContact O-ND2 3.35Å
279	Y	72.1	Confident	81.3	Confident	51 Å²	51	23.2 Å²	23.2	20%	0.2	12%	0.121	C	C	.	.	G	3₁₀ helix	trans	-70.2	-27.9	-173	-78.6	-106.4	0	0	0	114.3	T81 R160 G276 W277 N281 F282 T365	T81-Y279 HydrophobicContact CG2-CD2 4.3Å; T81-Y279 HydrophobicContact CG2-CG 4.28Å; R160-Y279 PolarHBondContact NH1-OH 3.38Å; R160-Y279 PolarHBondContact NH2-OH 3.5Å; G276-Y279 VanDerWaalsContact CA-CD2 3.48Å; G276-Y279 WeakPolarHBondContact O-CB 3.42Å; G276-Y279 VanDerWaalsContact O-CD2 3.26Å; G276-Y279 WeakPolarHBondContact O-CD2 3.3Å; G276-Y279 PolarHBondContact O-N 3.16Å; G276-Y279 VanDerWaalsContact O-N 3.15Å; W277-Y279 PolarHBondContact O-N 3.09Å; Y279-N281 PolarHBondContact O-N 3.43Å; Y279-N281 VanDerWaalsContact O-N 3.1Å; Y279-F282 HydrophobicContact CD1-CD2 4.1Å; Y279-F282 HydrophobicContact CD1-CE2 4.18Å; Y279-F282 HydrophobicContact CG-CD2 4.29Å; Y279-F282 HydrophobicContact CG-CE2 4.3Å; Y279-F282 WeakPolarHBondContact O-CD2 3.39Å; Y279-F282 PolarHBondContact O-N 2.77Å; Y279-T365 HydrophobicContact CD1-CG2 4.35Å; Y279-T365 HydrophobicContact CE1-CG2 4.28Å
280	L	72.8	Confident	81.2	Confident	1 Å²	1	23.3 Å²	23.3	1%	0.005	12%	0.122	C	C	.	.	G	3₁₀ helix	trans	-59.7	-25.7	177.2	-167.1	65.2	0	0	0	111.2	I77 I78 N278 F282 V283 T284 L294 A297	I77-L280 HydrophobicContact CG2-CD1 4.37Å; I78-L280 HydrophobicContact CD1-CB 4.08Å; I78-L280 HydrophobicContact CD1-CD2 3.42Å; I78-L280 VanDerWaalsContact CD1-CD2 3.42Å; I78-L280 HydrophobicContact CD1-CG 4.28Å; I78-L280 HydrophobicContact CG1-CB 3.98Å; I78-L280 HydrophobicContact CG1-CD2 3.96Å; I78-L280 HydrophobicContact CG1-CG 4.37Å; N278-L280 VanDerWaalsContact C-N 3.34Å; N278-L280 PolarHBondContact O-N 3.38Å; L280-F282 VanDerWaalsContact C-N 3.31Å; L280-F282 PolarHBondContact O-N 3.14Å; L280-V283 HydrophobicContact CD1-CG2 3.85Å; L280-V283 VanDerWaalsContact O-CG2 3.26Å; L280-V283 WeakPolarHBondContact O-CG2 3.38Å; L280-V283 PolarHBondContact O-N 3.43Å; L280-T284 PolarHBondContact O-N 3.06Å; L280-T284 PolarHBondContact O-OG1 3.48Å; L280-L294 HydrophobicContact CB-CD1 4.21Å; L280-L294 HydrophobicContact CD2-CD1 3.55Å; L280-L294 HydrophobicContact CG-CD1 3.68Å; L280-A297 HydrophobicContact CD2-CB 3.74Å
281	N	77.3	Confident	81	Confident	8 Å²	8	29.1 Å²	29.1	4%	0.043	14%	0.144	C	C	.	.	G	3₁₀ helix	trans	-67.4	-28.5	177	-63.7	-67.6	0	0	0	113.6	Y122 Y138 N278 Y279 V283 T284	Y122-N281 PolarHBondContact O-OD1 3.46Å; Y138-N281 WeakPolarHBondContact OH-CB 3.4Å; N278-N281 WeakPolarHBondContact O-CB 3.46Å; N278-N281 PolarHBondContact O-N 2.82Å; N278-N281 PolarHBondContact O-ND2 3.35Å; Y279-N281 PolarHBondContact O-N 3.43Å; Y279-N281 VanDerWaalsContact O-N 3.1Å; N281-V283 PolarHBondContact O-N 2.88Å; N281-T284 VanDerWaalsContact C-OG1 3.3Å; N281-T284 VanDerWaalsContact CA-OG1 3.25Å; N281-T284 WeakPolarHBondContact CA-OG1 3.26Å; N281-T284 PolarHBondContact O-N 3.19Å; N281-T284 PolarHBondContact O-OG1 2.95Å
282	F	70.1	Confident	80.8	Confident	38 Å²	38	33.8 Å²	33.8	17%	0.167	17%	0.165	C	C	.	.	G	3₁₀ helix	trans	-70.7	-20.2	176.8	-62.7	-76.2	0	0	0	112.8	G133 G134 Y279 L280	G133-F282 WeakPolarHBondContact O-CE1 3.38Å; G134-F282 VanDerWaalsContact CA-CE1 3.42Å; Y279-F282 HydrophobicContact CD1-CD2 4.1Å; Y279-F282 HydrophobicContact CD1-CE2 4.18Å; Y279-F282 HydrophobicContact CG-CD2 4.29Å; Y279-F282 HydrophobicContact CG-CE2 4.3Å; Y279-F282 WeakPolarHBondContact O-CD2 3.39Å; Y279-F282 PolarHBondContact O-N 2.77Å; L280-F282 VanDerWaalsContact C-N 3.31Å; L280-F282 PolarHBondContact O-N 3.14Å
283	V	69.4	Low	80.9	Confident	22 Å²	22	33.6 Å²	33.6	13%	0.133	16%	0.164	C	C	.	.	G	3₁₀ helix	trans	-110.6	16.3	-178.7	-61.7	0	0	0	0	112.3	I69 L280 N281 E285 E286 M287	I69-V283 HydrophobicContact CD1-CB 3.77Å; I69-V283 HydrophobicContact CD1-CG1 4.42Å; I69-V283 HydrophobicContact CD1-CG2 4.02Å; L280-V283 HydrophobicContact CD1-CG2 3.85Å; L280-V283 VanDerWaalsContact O-CG2 3.26Å; L280-V283 WeakPolarHBondContact O-CG2 3.38Å; L280-V283 PolarHBondContact O-N 3.43Å; N281-V283 PolarHBondContact O-N 2.88Å; V283-E285 VanDerWaalsContact C-N 3.27Å; V283-E285 PolarHBondContact O-N 3.07Å; V283-E286 PolarHBondContact O-N 2.93Å; V283-E286 VanDerWaalsContact O-N 3.12Å; V283-M287 PolarHBondContact O-N 3.45Å
284	T	73.8	Confident	80.7	Confident	9 Å²	9	33.5 Å²	33.5	6%	0.055	16%	0.164	C	C	.	.	G	3₁₀ helix	trans	-60.1	-37.5	179.5	-49.2	0	0	0	0	112.1	L280 N281 E286 M287 P290 L294	L280-T284 PolarHBondContact O-N 3.06Å; L280-T284 PolarHBondContact O-OG1 3.48Å; N281-T284 VanDerWaalsContact C-OG1 3.3Å; N281-T284 VanDerWaalsContact CA-OG1 3.25Å; N281-T284 WeakPolarHBondContact CA-OG1 3.26Å; N281-T284 PolarHBondContact O-N 3.19Å; N281-T284 PolarHBondContact O-OG1 2.95Å; T284-E286 VanDerWaalsContact C-N 3.25Å; T284-E286 PolarHBondContact O-N 3.3Å; T284-M287 HydrophobicContact CG2-CE 4.27Å; T284-M287 PolarHBondContact O-N 3.47Å; T284-P290 HydrophobicContact CG2-CB 3.7Å; T284-L294 HydrophobicContact CG2-CD2 4.49Å
285	E	73	Confident	80.7	Confident	66 Å²	66	34.5 Å²	34.5	31%	0.308	17%	0.17	S	C	.	.	G	3₁₀ helix	trans	-62.4	-32.8	177.2	-69.6	-178.4	177.3	0	0	112.5	R67 S130 S132 V283	R67-E285 WeakPolarHBondContact CG-O 3.38Å; S130-E285 WeakPolarHBondContact O-CG 3.34Å; S132-E285 WeakPolarHBondContact CB-OE1 3.49Å; S132-E285 PolarHBondContact N-OE1 3.22Å; V283-E285 VanDerWaalsContact C-N 3.27Å; V283-E285 PolarHBondContact O-N 3.07Å
286	E	78.1	Confident	81	Confident	38 Å²	38	39.5 Å²	39.5	18%	0.178	18%	0.179	C	C	.	.	G	3₁₀ helix	trans	-86.8	-5.5	-178.8	-61.2	179.2	-114	0	0	112.5	L65 R67 T68 I69 V283 T284 R368	L65-E286 HydrophobicContact CB-CG 4.15Å; L65-E286 HydrophobicContact CD1-CG 4.28Å; R67-E286 CarbonylContact C-O 3.6Å; R67-E286 VanDerWaalsContact CA-O 3.32Å; R67-E286 WeakPolarHBondContact CA-O 3.47Å; T68-E286 PolarHBondContact N-O 3.17Å; I69-E286 HydrophobicContact CD1-CB 3.75Å; I69-E286 HydrophobicContact CG1-CB 4.16Å; I69-E286 PolarHBondContact N-O 2.95Å; V283-E286 PolarHBondContact O-N 2.93Å; V283-E286 VanDerWaalsContact O-N 3.12Å; T284-E286 VanDerWaalsContact C-N 3.25Å; T284-E286 PolarHBondContact O-N 3.3Å; E286-R368 IonicContact OE1-NH1 3.37Å
287	M	80.1	Confident	81.4	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	18%	0.176	C	C	.	.	B	Isolated β-bridge	trans	-87.1	138.9	-176.5	-176.9	164.8	41.6	0	0	113.1	I69 V283 T284 P290 N293 L294	I69-M287 HydrophobicContact CB-CB 4.44Å; V283-M287 PolarHBondContact O-N 3.45Å; T284-M287 HydrophobicContact CG2-CE 4.27Å; T284-M287 PolarHBondContact O-N 3.47Å; M287-P290 HydrophobicContact CB-CB 4.45Å; M287-P290 HydrophobicContact CE-CB 3.85Å; M287-N293 HydrophobicContact CG-CB 4.36Å; M287-N293 HydrophobicContact SD-CB 3.97Å; M287-L294 HydrophobicContact CE-CB 3.49Å; M287-L294 VanDerWaalsContact CE-CB 3.49Å; M287-L294 HydrophobicContact CE-CD1 3.66Å; M287-L294 HydrophobicContact CE-CG 4.09Å; M287-L294 HydrophobicContact SD-CB 4.47Å
288	I	85.3	Confident	81.6	Confident	65 Å²	65	39 Å²	39	33%	0.333	18%	0.175	S	C	.	.	S	Bend	trans	-75.7	129.8	173.3	-59.6	172	0	0	0	108.3	R67 I69 T70 N293	R67-I288 HydrophobicContact CB-CG1 4.37Å; I69-I288 PolarHBondContact O-N 3.5Å; T70-I288 HydrophobicContact CG2-CD1 4.06Å; I288-N293 PolarHBondContact O-ND2 3.2Å
289	E	85.3	Confident	82	Confident	97 Å²	97	42.7 Å²	42.7	45%	0.453	19%	0.194	S	C	.	.	S	Bend	trans	44.7	62.3	-177.4	-67.2	-171.7	105.4	0	0	113.7	Y291 K292 N293	E289-Y291 PolarHBondContact O-N 3.05Å; E289-Y291 VanDerWaalsContact O-N 3.13Å; E289-K292 PolarHBondContact O-N 3.42Å; E289-K292 IonicContact OE1-NZ 2.84Å; E289-K292 PolarHBondContact OE1-NZ 2.99Å; E289-N293 PolarHBondContact O-N 3.47Å
290	P	83.4	Confident	83	Confident	9 Å²	9	43.9 Å²	43.9	6%	0.058	20%	0.204	C	C	.	.	H	α-helix	trans	-59.2	-32.9	-171.1	23	-32.9	0	0	0	113	T284 M287 K292 L294	T284-P290 HydrophobicContact CG2-CB 3.7Å; M287-P290 HydrophobicContact CB-CB 4.45Å; M287-P290 HydrophobicContact CE-CB 3.85Å; P290-K292 PolarHBondContact O-N 2.98Å; P290-L294 WeakPolarHBondContact O-CB 3.31Å; P290-L294 PolarHBondContact O-N 3.47Å
291	Y	86.2	Confident	83.8	Confident	121 Å²	121	43.9 Å²	43.9	48%	0.475	20%	0.203	S	C	.	.	H	α-helix	trans	-61.8	-27.3	179.1	-52.1	-43.4	0	0	0	114.4	T127 E289 P448	T127-Y291 HydrophobicContact CG2-CD1 3.72Å; T127-Y291 HydrophobicContact CG2-CE1 4.31Å; E289-Y291 PolarHBondContact O-N 3.05Å; E289-Y291 VanDerWaalsContact O-N 3.13Å; Y291-P448 HydrophobicContact CD1-CB 3.44Å; Y291-P448 VanDerWaalsContact CD1-CB 3.44Å; Y291-P448 HydrophobicContact CD1-CG 3.63Å; Y291-P448 HydrophobicContact CD2-CB 4.32Å; Y291-P448 HydrophobicContact CE1-CB 3.87Å; Y291-P448 HydrophobicContact CE1-CG 3.47Å; Y291-P448 VanDerWaalsContact CE1-CG 3.47Å; Y291-P448 HydrophobicContact CE2-CG 4.37Å; Y291-P448 HydrophobicContact CG-CB 3.71Å; Y291-P448 HydrophobicContact CG-CG 4.19Å
292	K	87.6	Confident	84.6	Confident	103 Å²	103	43.5 Å²	43.5	45%	0.448	20%	0.201	S	C	.	.	H	α-helix	trans	-102.4	-41.8	177.6	-63.6	175.8	-169.5	157.2	0	111.3	E289 P290 P295 R296	E289-K292 PolarHBondContact O-N 3.42Å; E289-K292 IonicContact OE1-NZ 2.84Å; E289-K292 PolarHBondContact OE1-NZ 2.99Å; P290-K292 PolarHBondContact O-N 2.98Å; K292-P295 WeakPolarHBondContact O-CD 3.12Å; K292-P295 WeakPolarHBondContact O-CG 3.35Å; K292-R296 WeakPolarHBondContact O-CB 3.4Å; K292-R296 VanDerWaalsContact O-CD 3.28Å; K292-R296 WeakPolarHBondContact O-CD 3.08Å; K292-R296 WeakPolarHBondContact O-CG 3.39Å; K292-R296 PolarHBondContact O-N 3.36Å
293	N	88.6	Confident	85.7	Confident	15 Å²	15	44.8 Å²	44.8	8%	0.08	21%	0.214	C	C	.	.	H	α-helix	trans	-81.4	-31.5	-170.1	-69.9	-22.2	0	0	0	112.9	L71 M287 I288 E289 A297	L71-N293 HydrophobicContact CB-CB 4.34Å; L71-N293 HydrophobicContact CD1-CB 4.24Å; L71-N293 WeakPolarHBondContact CD1-O 3.25Å; M287-N293 HydrophobicContact CG-CB 4.36Å; M287-N293 HydrophobicContact SD-CB 3.97Å; I288-N293 PolarHBondContact O-ND2 3.2Å; E289-N293 PolarHBondContact O-N 3.47Å; N293-A297 VanDerWaalsContact O-CB 3.23Å; N293-A297 WeakPolarHBondContact O-CB 3.26Å; N293-A297 PolarHBondContact O-N 3.47Å
294	L	86.8	Confident	86.9	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-58	-57	175	-173.1	66.7	0	0	0	112.5	A123 T127 L280 T284 M287 P290 R296 A297 I298	A123-L294 HydrophobicContact CB-CD2 3.99Å; A123-L294 HydrophobicContact CB-CG 4.14Å; T127-L294 HydrophobicContact CG2-CD2 3.89Å; L280-L294 HydrophobicContact CB-CD1 4.21Å; L280-L294 HydrophobicContact CD2-CD1 3.55Å; L280-L294 HydrophobicContact CG-CD1 3.68Å; T284-L294 HydrophobicContact CG2-CD2 4.49Å; M287-L294 HydrophobicContact CE-CB 3.49Å; M287-L294 VanDerWaalsContact CE-CB 3.49Å; M287-L294 HydrophobicContact CE-CD1 3.66Å; M287-L294 HydrophobicContact CE-CG 4.09Å; M287-L294 HydrophobicContact SD-CB 4.47Å; P290-L294 WeakPolarHBondContact O-CB 3.31Å; P290-L294 PolarHBondContact O-N 3.47Å; L294-R296 PolarHBondContact O-N 2.84Å; L294-A297 PolarHBondContact O-N 3.04Å; L294-I298 HydrophobicContact CD1-CD1 4.4Å; L294-I298 HydrophobicContact CG-CD1 4.3Å; L294-I298 WeakPolarHBondContact O-CG1 3.46Å; L294-I298 PolarHBondContact O-N 3.18Å
295	P	89.4	Confident	87.8	Confident	22 Å²	22	46.9 Å²	46.9	14%	0.143	22%	0.223	C	C	.	.	H	α-helix	trans	-67.5	-36.3	-178.4	27.2	-36.3	0	0	0	112.1	K292 I298 I299 I449	K292-P295 WeakPolarHBondContact O-CD 3.12Å; K292-P295 WeakPolarHBondContact O-CG 3.35Å; P295-I298 PolarHBondContact O-N 3.41Å; P295-I299 WeakPolarHBondContact O-CB 3.46Å; P295-I299 VanDerWaalsContact O-CG1 3.3Å; P295-I299 WeakPolarHBondContact O-CG1 3.45Å; P295-I299 PolarHBondContact O-N 3.35Å; P295-I449 HydrophobicContact CB-CD1 4.11Å; P295-I449 HydrophobicContact CG-CD1 3.63Å
296	R	90.4	Very high	88.8	Confident	136 Å²	136	44.8 Å²	44.8	51%	0.513	22%	0.215	S	C	.	.	H	α-helix	trans	-63.2	-43.1	176.4	-73.4	174.8	-178.3	-176.3	-2.5	111.5	L71 K292 L294 I298 I299 I300	L71-R296 HydrophobicContact CD1-CB 3.71Å; L71-R296 HydrophobicContact CD2-CB 4.43Å; K292-R296 WeakPolarHBondContact O-CB 3.4Å; K292-R296 VanDerWaalsContact O-CD 3.28Å; K292-R296 WeakPolarHBondContact O-CD 3.08Å; K292-R296 WeakPolarHBondContact O-CG 3.39Å; K292-R296 PolarHBondContact O-N 3.36Å; L294-R296 PolarHBondContact O-N 2.84Å; R296-I298 VanDerWaalsContact C-N 3.3Å; R296-I298 PolarHBondContact O-N 2.83Å; R296-I299 PolarHBondContact O-N 2.89Å; R296-I300 WeakPolarHBondContact O-CB 3.33Å; R296-I300 WeakPolarHBondContact O-CD1 3.47Å; R296-I300 WeakPolarHBondContact O-CG1 3.46Å; R296-I300 PolarHBondContact O-N 3.42Å
297	A	89.9	Confident	89.6	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-59.7	-43.4	176.8	0	0	0	0	0	111.1	L71 V75 I78 L280 N293 L294 S301	L71-A297 HydrophobicContact CD1-CB 3.99Å; V75-A297 HydrophobicContact CG2-CB 4.17Å; I78-A297 HydrophobicContact CD1-CB 4.27Å; L280-A297 HydrophobicContact CD2-CB 3.74Å; N293-A297 VanDerWaalsContact O-CB 3.23Å; N293-A297 WeakPolarHBondContact O-CB 3.26Å; N293-A297 PolarHBondContact O-N 3.47Å; L294-A297 PolarHBondContact O-N 3.04Å; A297-S301 WeakPolarHBondContact O-CB 3.4Å; A297-S301 PolarHBondContact O-N 2.84Å; A297-S301 PolarHBondContact O-OG 3.22Å
298	I	90.8	Very high	90.3	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.005	24%	0.235	C	C	.	.	H	α-helix	trans	-65.1	-49.8	179	-69.7	164.9	0	0	0	111.8	I78 A119 L120 A123 L294 P295 R296 I300 S301 L302	I78-I298 HydrophobicContact CD1-CG1 3.82Å; A119-I298 HydrophobicContact CB-CD1 4.24Å; A119-I298 HydrophobicContact CB-CG1 4.32Å; A119-I298 HydrophobicContact CB-CG2 3.45Å; A119-I298 VanDerWaalsContact CB-CG2 3.45Å; L120-I298 HydrophobicContact CD2-CG2 4.36Å; L120-I298 HydrophobicContact CG-CG2 4.45Å; A123-I298 HydrophobicContact CB-CD1 3.77Å; L294-I298 HydrophobicContact CD1-CD1 4.4Å; L294-I298 HydrophobicContact CG-CD1 4.3Å; L294-I298 WeakPolarHBondContact O-CG1 3.46Å; L294-I298 PolarHBondContact O-N 3.18Å; P295-I298 PolarHBondContact O-N 3.41Å; R296-I298 VanDerWaalsContact C-N 3.3Å; R296-I298 PolarHBondContact O-N 2.83Å; I298-I300 PolarHBondContact O-N 3.28Å; I298-S301 PolarHBondContact O-N 3.4Å; I298-S301 PolarHBondContact O-OG 3.2Å; I298-L302 HydrophobicContact CG2-CD1 3.86Å; I298-L302 PolarHBondContact O-N 3.13Å; I298-L302 VanDerWaalsContact O-N 3.09Å
299	I	91.3	Very high	90.8	Very high	94 Å²	94	43.7 Å²	43.7	48%	0.482	22%	0.219	S	C	.	.	H	α-helix	trans	-65.2	-28.5	-177.7	-68	168	0	0	0	111.7	L120 P295 R296 P303	L120-I299 HydrophobicContact CD2-CD1 4.13Å; L120-I299 HydrophobicContact CD2-CG1 3.95Å; P295-I299 WeakPolarHBondContact O-CB 3.46Å; P295-I299 VanDerWaalsContact O-CG1 3.3Å; P295-I299 WeakPolarHBondContact O-CG1 3.45Å; P295-I299 PolarHBondContact O-N 3.35Å; R296-I299 PolarHBondContact O-N 2.89Å; I299-P303 WeakPolarHBondContact O-CD 3.25Å; I299-P303 WeakPolarHBondContact O-CG 3.41Å
300	I	92.8	Very high	91.2	Very high	77 Å²	77	40.7 Å²	40.7	40%	0.395	21%	0.207	S	C	.	.	H	α-helix	trans	-82	-49.2	175.8	-65.8	166.7	0	0	0	110.6	V75 R296 I298 I304	V75-I300 HydrophobicContact CG1-CG2 4.19Å; V75-I300 HydrophobicContact CG2-CB 4.23Å; V75-I300 HydrophobicContact CG2-CG2 4.13Å; R296-I300 WeakPolarHBondContact O-CB 3.33Å; R296-I300 WeakPolarHBondContact O-CD1 3.47Å; R296-I300 WeakPolarHBondContact O-CG1 3.46Å; R296-I300 PolarHBondContact O-N 3.42Å; I298-I300 PolarHBondContact O-N 3.28Å; I300-I304 HydrophobicContact CG2-CD1 3.73Å; I300-I304 VanDerWaalsContact O-CD1 3.3Å; I300-I304 WeakPolarHBondContact O-CD1 3.43Å; I300-I304 VanDerWaalsContact O-CG1 3.23Å; I300-I304 WeakPolarHBondContact O-CG1 3.27Å; I300-I304 PolarHBondContact O-N 3.28Å
301	S	91.3	Very high	91.7	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-69.4	-43.9	-170.8	55.2	0	0	0	0	113.8	I78 A297 I298 I304 V305	I78-S301 WeakPolarHBondContact CD1-OG 3.1Å; I78-S301 WeakPolarHBondContact CG2-OG 3.09Å; A297-S301 WeakPolarHBondContact O-CB 3.4Å; A297-S301 PolarHBondContact O-N 2.84Å; A297-S301 PolarHBondContact O-OG 3.22Å; I298-S301 PolarHBondContact O-N 3.4Å; I298-S301 PolarHBondContact O-OG 3.2Å; S301-I304 WeakPolarHBondContact O-CB 3.17Å; S301-I304 PolarHBondContact O-N 3.07Å; S301-V305 WeakPolarHBondContact O-CG2 3.27Å; S301-V305 PolarHBondContact O-N 3.45Å
302	L	93.1	Very high	92.1	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-69.2	-40.9	-173.4	-73.2	177	0	0	0	114.4	I82 T116 A119 W277 I298 I304 V305 T306	I82-L302 HydrophobicContact CD1-CD2 3.35Å; T116-L302 VanDerWaalsContact CA-CD1 3.41Å; T116-L302 HydrophobicContact CG2-CD1 4.41Å; T116-L302 WeakPolarHBondContact OG1-CB 3.33Å; A119-L302 HydrophobicContact CB-CD1 3.53Å; W277-L302 HydrophobicContact CB-CD1 4.43Å; W277-L302 HydrophobicContact CB-CD2 4.12Å; I298-L302 HydrophobicContact CG2-CD1 3.86Å; I298-L302 PolarHBondContact O-N 3.13Å; I298-L302 VanDerWaalsContact O-N 3.09Å; L302-I304 VanDerWaalsContact C-N 3.31Å; L302-I304 PolarHBondContact O-N 3.36Å; L302-V305 PolarHBondContact O-N 2.88Å; L302-T306 WeakPolarHBondContact O-CB 3.46Å; L302-T306 PolarHBondContact O-N 3.41Å; L302-T306 PolarHBondContact O-OG1 3.4Å
303	P	94.1	Very high	92.3	Very high	66 Å²	66	32.2 Å²	32.2	43%	0.429	17%	0.174	S	C	.	.	H	α-helix	trans	-61.7	-37.6	170	-27.9	38.6	0	0	0	113	I299 T306 A307	I299-P303 WeakPolarHBondContact O-CD 3.25Å; I299-P303 WeakPolarHBondContact O-CG 3.41Å; P303-T306 PolarHBondContact O-N 3.01Å; P303-A307 WeakPolarHBondContact O-CB 3.04Å; P303-A307 PolarHBondContact O-N 3.35Å
304	I	92.8	Very high	92.5	Very high	75 Å²	75	33.5 Å²	33.5	39%	0.385	18%	0.18	S	C	.	.	H	α-helix	trans	-61.2	-49.5	175.2	-69.4	168.9	0	0	0	110.2	I300 S301 L302 T306 A307 V308	I300-I304 HydrophobicContact CG2-CD1 3.73Å; I300-I304 VanDerWaalsContact O-CD1 3.3Å; I300-I304 WeakPolarHBondContact O-CD1 3.43Å; I300-I304 VanDerWaalsContact O-CG1 3.23Å; I300-I304 WeakPolarHBondContact O-CG1 3.27Å; I300-I304 PolarHBondContact O-N 3.28Å; S301-I304 WeakPolarHBondContact O-CB 3.17Å; S301-I304 PolarHBondContact O-N 3.07Å; L302-I304 VanDerWaalsContact C-N 3.31Å; L302-I304 PolarHBondContact O-N 3.36Å; I304-T306 VanDerWaalsContact C-N 3.32Å; I304-T306 PolarHBondContact O-N 2.78Å; I304-A307 PolarHBondContact O-N 3.41Å; I304-V308 HydrophobicContact CG2-CG2 4.48Å; I304-V308 VanDerWaalsContact O-CG2 3.31Å; I304-V308 WeakPolarHBondContact O-CG2 3.37Å; I304-V308 PolarHBondContact O-N 3.2Å
305	V	93.4	Very high	92.7	Very high	0 Å²	0	33.6 Å²	33.6	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60.2	-44.3	177.8	174.4	0	0	0	0	110.9	V79 I82 I83 Y274 S301 L302 A307 V308 Y309	V79-V305 HydrophobicContact CG2-CG2 4.27Å; I82-V305 HydrophobicContact CB-CG1 4.41Å; I82-V305 HydrophobicContact CB-CG2 4.36Å; I82-V305 HydrophobicContact CG2-CG1 3.67Å; I82-V305 HydrophobicContact CG2-CG2 4.47Å; I83-V305 HydrophobicContact CD1-CG2 4.29Å; I83-V305 HydrophobicContact CG1-CG1 4.27Å; I83-V305 HydrophobicContact CG1-CG2 4.01Å; Y274-V305 HydrophobicContact CD1-CG1 3.99Å; Y274-V305 HydrophobicContact CE1-CG1 3.88Å; S301-V305 WeakPolarHBondContact O-CG2 3.27Å; S301-V305 PolarHBondContact O-N 3.45Å; L302-V305 PolarHBondContact O-N 2.88Å; V305-A307 PolarHBondContact O-N 3.02Å; V305-V308 PolarHBondContact O-N 3.38Å; V305-Y309 HydrophobicContact CG1-CD1 4.35Å; V305-Y309 HydrophobicContact CG1-CD2 3.9Å; V305-Y309 HydrophobicContact CG1-CE1 4.13Å; V305-Y309 HydrophobicContact CG1-CE2 3.66Å; V305-Y309 HydrophobicContact CG1-CG 4.27Å; V305-Y309 WeakPolarHBondContact O-CB 3.02Å; V305-Y309 PolarHBondContact O-N 2.77Å
306	T	95.3	Very high	92.8	Very high	22 Å²	22	32.5 Å²	32.5	14%	0.135	17%	0.174	C	C	.	.	H	α-helix	trans	-59.8	-46.6	178.7	-53.8	0	0	0	0	111.2	G112 Y274 L302 P303 I304 Y309 V310	G112-T306 VanDerWaalsContact CA-OG1 3.32Å; G112-T306 WeakPolarHBondContact CA-OG1 3.42Å; Y274-T306 WeakPolarHBondContact OH-CA 3.35Å; L302-T306 WeakPolarHBondContact O-CB 3.46Å; L302-T306 PolarHBondContact O-N 3.41Å; L302-T306 PolarHBondContact O-OG1 3.4Å; P303-T306 PolarHBondContact O-N 3.01Å; I304-T306 VanDerWaalsContact C-N 3.32Å; I304-T306 PolarHBondContact O-N 2.78Å; T306-Y309 PolarHBondContact O-N 3.46Å; T306-V310 HydrophobicContact CG2-CG2 4.4Å; T306-V310 WeakPolarHBondContact O-CB 3.49Å; T306-V310 VanDerWaalsContact O-CG2 3.3Å; T306-V310 WeakPolarHBondContact O-CG2 3.43Å; T306-V310 PolarHBondContact O-N 3.33Å
307	A	94.9	Very high	92.7	Very high	49 Å²	49	26.4 Å²	26.4	41%	0.405	15%	0.152	S	C	.	.	H	α-helix	trans	-60.9	-47.2	176.3	0	0	0	0	0	111.4	P303 I304 V305 Y309 V310 L311	P303-A307 WeakPolarHBondContact O-CB 3.04Å; P303-A307 PolarHBondContact O-N 3.35Å; I304-A307 PolarHBondContact O-N 3.41Å; V305-A307 PolarHBondContact O-N 3.02Å; A307-Y309 VanDerWaalsContact C-N 3.33Å; A307-Y309 PolarHBondContact O-N 2.87Å; A307-V310 PolarHBondContact O-N 3.19Å; A307-L311 VanDerWaalsContact O-CB 3.24Å; A307-L311 WeakPolarHBondContact O-CB 3.42Å; A307-L311 WeakPolarHBondContact O-CG 3.29Å; A307-L311 PolarHBondContact O-N 3.42Å
308	V	93.8	Very high	92.6	Very high	31 Å²	31	26.7 Å²	26.7	19%	0.188	15%	0.153	C	C	.	.	H	α-helix	trans	-59.1	-44.9	177.9	170.7	0	0	0	0	111.1	I83 L227 I231 I304 V305 T312	I83-V308 HydrophobicContact CD1-CG1 4.27Å; L227-V308 HydrophobicContact CB-CG1 4.45Å; L227-V308 HydrophobicContact CD1-CG1 3.99Å; I231-V308 HydrophobicContact CD1-CG1 4.2Å; I304-V308 HydrophobicContact CG2-CG2 4.48Å; I304-V308 VanDerWaalsContact O-CG2 3.31Å; I304-V308 WeakPolarHBondContact O-CG2 3.37Å; I304-V308 PolarHBondContact O-N 3.2Å; V305-V308 PolarHBondContact O-N 3.38Å; V308-T312 VanDerWaalsContact O-CB 3.31Å; V308-T312 WeakPolarHBondContact O-CB 3.09Å; V308-T312 PolarHBondContact O-N 3.2Å; V308-T312 PolarHBondContact O-OG1 3.46Å
309	Y	94.8	Very high	92.3	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-68.5	-44.7	-179.1	-73.5	-1.7	0	0	0	112.9	I82 I83 I87 W108 A273 Y274 V305 T306 A307 L311 T312 N313	I82-Y309 HydrophobicContact CG2-CE2 4.43Å; I82-Y309 PolarHBondContact O-OH 3.13Å; I83-Y309 WeakPolarHBondContact CA-OH 3.29Å; I83-Y309 HydrophobicContact CG1-CE1 4.11Å; I83-Y309 HydrophobicContact CG2-CE1 4.49Å; I87-Y309 HydrophobicContact CB-CD1 4.08Å; I87-Y309 HydrophobicContact CB-CE1 3.69Å; I87-Y309 HydrophobicContact CD1-CD1 3.63Å; I87-Y309 HydrophobicContact CD1-CD2 4.41Å; I87-Y309 HydrophobicContact CD1-CE1 4.13Å; I87-Y309 HydrophobicContact CD1-CG 3.77Å; I87-Y309 HydrophobicContact CG1-CD1 3.7Å; I87-Y309 HydrophobicContact CG1-CE1 3.85Å; I87-Y309 HydrophobicContact CG1-CG 4.35Å; I87-Y309 HydrophobicContact CG2-CE1 4.23Å; W108-Y309 AromaticContact CE3-CD2 3.85Å; W108-Y309 HydrophobicContact CE3-CD2 3.85Å; W108-Y309 HydrophobicContact CE3-CG 4.22Å; W108-Y309 HydrophobicContact CH2-CD2 4.38Å; W108-Y309 AromaticContact CZ3-CD2 3.36Å; W108-Y309 HydrophobicContact CZ3-CD2 3.36Å; W108-Y309 AromaticContact CZ3-CE2 3.97Å; W108-Y309 HydrophobicContact CZ3-CE2 3.97Å; W108-Y309 AromaticContact CZ3-CG 3.87Å; W108-Y309 HydrophobicContact CZ3-CG 3.87Å; A273-Y309 HydrophobicContact CB-CE2 4.02Å; A273-Y309 VanDerWaalsContact O-CE2 3.25Å; A273-Y309 WeakPolarHBondContact O-CE2 3.37Å; A273-Y309 PolarHBondContact O-OH 2.91Å; Y274-Y309 HydrophobicContact CD1-CD2 4.12Å; Y274-Y309 HydrophobicContact CD1-CE2 4.09Å; Y274-Y309 HydrophobicContact CD2-CD2 4.24Å; Y274-Y309 HydrophobicContact CD2-CE2 4.36Å; Y274-Y309 AromaticContact CE1-CD2 3.65Å; Y274-Y309 HydrophobicContact CE1-CD2 3.65Å; Y274-Y309 HydrophobicContact CE1-CE2 4.09Å; Y274-Y309 AromaticContact CE2-CD2 3.81Å; Y274-Y309 HydrophobicContact CE2-CD2 3.81Å; Y274-Y309 HydrophobicContact CE2-CE2 4.38Å; Y274-Y309 HydrophobicContact CG-CD2 4.4Å; Y274-Y309 HydrophobicContact CG-CE2 4.23Å; Y274-Y309 AromaticContact CZ-CD2 3.5Å; Y274-Y309 VanDerWaalsContact CZ-CD2 3.5Å; V305-Y309 HydrophobicContact CG1-CD1 4.35Å; V305-Y309 HydrophobicContact CG1-CD2 3.9Å; V305-Y309 HydrophobicContact CG1-CE1 4.13Å; V305-Y309 HydrophobicContact CG1-CE2 3.66Å; V305-Y309 HydrophobicContact CG1-CG 4.27Å; V305-Y309 WeakPolarHBondContact O-CB 3.02Å; V305-Y309 PolarHBondContact O-N 2.77Å; T306-Y309 PolarHBondContact O-N 3.46Å; A307-Y309 VanDerWaalsContact C-N 3.33Å; A307-Y309 PolarHBondContact O-N 2.87Å; Y309-L311 VanDerWaalsContact C-N 3.35Å; Y309-L311 PolarHBondContact O-N 2.98Å; Y309-T312 PolarHBondContact O-N 3.48Å; Y309-N313 PolarHBondContact O-N 3.34Å; Y309-N313 PolarHBondContact O-ND2 3.18Å
310	V	95.1	Very high	92	Very high	33 Å²	33	24 Å²	24	20%	0.2	14%	0.141	C	C	.	.	H	α-helix	trans	-62.1	-44.4	175.9	172.3	0	0	0	0	110.5	L105 W108 T306 A307 T312 N313 L314	L105-V310 HydrophobicContact CD2-CG1 4.43Å; W108-V310 HydrophobicContact CB-CG2 4.11Å; T306-V310 HydrophobicContact CG2-CG2 4.4Å; T306-V310 WeakPolarHBondContact O-CB 3.49Å; T306-V310 VanDerWaalsContact O-CG2 3.3Å; T306-V310 WeakPolarHBondContact O-CG2 3.43Å; T306-V310 PolarHBondContact O-N 3.33Å; A307-V310 PolarHBondContact O-N 3.19Å; V310-T312 VanDerWaalsContact C-N 3.35Å; V310-T312 PolarHBondContact O-N 2.83Å; V310-N313 PolarHBondContact O-N 3.1Å; V310-L314 VanDerWaalsContact O-CB 3.31Å; V310-L314 WeakPolarHBondContact O-CB 3.36Å; V310-L314 PolarHBondContact O-N 3.4Å
311	L	94.3	Very high	91.8	Very high	55 Å²	55	22.3 Å²	22.3	29%	0.288	14%	0.136	S	C	.	.	H	α-helix	trans	-65.6	-36.2	177.6	-70.1	175.6	0	0	0	112.8	I231 F235 A307 Y309 L314 A315	I231-L311 HydrophobicContact CD1-CB 4.03Å; I231-L311 HydrophobicContact CG1-CB 4.06Å; I231-L311 HydrophobicContact CG2-CB 4.23Å; I231-L311 HydrophobicContact CG2-CD1 4.41Å; F235-L311 HydrophobicContact CE2-CD1 4.42Å; F235-L311 HydrophobicContact CE2-CD2 3.93Å; F235-L311 HydrophobicContact CZ-CD2 3.63Å; A307-L311 VanDerWaalsContact O-CB 3.24Å; A307-L311 WeakPolarHBondContact O-CB 3.42Å; A307-L311 WeakPolarHBondContact O-CG 3.29Å; A307-L311 PolarHBondContact O-N 3.42Å; Y309-L311 VanDerWaalsContact C-N 3.35Å; Y309-L311 PolarHBondContact O-N 2.98Å; L311-L314 HydrophobicContact CD2-CD2 4.43Å; L311-A315 WeakPolarHBondContact O-CB 3.37Å; L311-A315 PolarHBondContact O-N 3.34Å
312	T	93.1	Very high	91.4	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-67	-45.4	176.5	-56.5	0	0	0	0	110.9	I87 L227 I230 V308 Y309 V310 A315 Y316	I87-T312 HydrophobicContact CG1-CG2 4.15Å; L227-T312 HydrophobicContact CD2-CG2 3.88Å; I230-T312 HydrophobicContact CG2-CG2 4.08Å; V308-T312 VanDerWaalsContact O-CB 3.31Å; V308-T312 WeakPolarHBondContact O-CB 3.09Å; V308-T312 PolarHBondContact O-N 3.2Å; V308-T312 PolarHBondContact O-OG1 3.46Å; Y309-T312 PolarHBondContact O-N 3.48Å; V310-T312 VanDerWaalsContact C-N 3.35Å; V310-T312 PolarHBondContact O-N 2.83Å; T312-A315 WeakPolarHBondContact O-CB 3.35Å; T312-A315 PolarHBondContact O-N 3.12Å; T312-Y316 HydrophobicContact CG2-CD2 4.48Å; T312-Y316 HydrophobicContact CG2-CE1 4.44Å; T312-Y316 HydrophobicContact CG2-CE2 3.8Å; T312-Y316 PolarHBondContact O-N 3.46Å
313	N	93.3	Very high	91.1	Very high	1 Å²	1	30.9 Å²	30.9	1%	0.005	18%	0.178	C	C	.	.	H	α-helix	trans	-65.6	-40.6	176.3	-77.3	-86.7	0	0	0	111.5	P91 L105 W108 Y309 V310 A315 Y316 F317	P91-N313 WeakPolarHBondContact CB-OD1 3.27Å; L105-N313 HydrophobicContact CD2-CB 3.9Å; W108-N313 WeakPolarHBondContact CZ2-ND2 3.41Å; W108-N313 PolarHBondContact NE1-ND2 3.46Å; W108-N313 PolarHBondContact NE1-OD1 3.25Å; Y309-N313 PolarHBondContact O-N 3.34Å; Y309-N313 PolarHBondContact O-ND2 3.18Å; V310-N313 PolarHBondContact O-N 3.1Å; N313-A315 VanDerWaalsContact C-N 3.27Å; N313-A315 PolarHBondContact O-N 3.27Å; N313-Y316 PolarHBondContact O-N 3.08Å; N313-Y316 VanDerWaalsContact O-N 3.11Å; N313-F317 HydrophobicContact CB-CD2 4.49Å; N313-F317 HydrophobicContact CB-CE2 4.19Å; N313-F317 WeakPolarHBondContact O-CD2 3.41Å; N313-F317 WeakPolarHBondContact O-CG 3.45Å; N313-F317 PolarHBondContact O-N 3.01Å
314	L	91.6	Very high	90.7	Very high	41 Å²	41	30.6 Å²	30.6	22%	0.215	17%	0.173	C	C	.	.	H	α-helix	trans	-55.5	-45.2	172.5	-178.9	64.3	0	0	0	110.9	L105 I238 L247 V310 L311 Y316 F317 T318	L105-L314 HydrophobicContact CD1-CD1 4.36Å; I238-L314 HydrophobicContact CD1-CD2 4.26Å; I238-L314 HydrophobicContact CD1-CG 4.41Å; L247-L314 HydrophobicContact CD1-CD1 3.79Å; L247-L314 HydrophobicContact CD2-CD1 3.58Å; L247-L314 HydrophobicContact CG-CD1 4.33Å; V310-L314 VanDerWaalsContact O-CB 3.31Å; V310-L314 WeakPolarHBondContact O-CB 3.36Å; V310-L314 PolarHBondContact O-N 3.4Å; L311-L314 HydrophobicContact CD2-CD2 4.43Å; L314-Y316 PolarHBondContact O-N 2.69Å; L314-F317 PolarHBondContact O-N 2.93Å; L314-T318 WeakPolarHBondContact O-CG2 3.4Å; L314-T318 PolarHBondContact O-N 2.8Å; L314-T318 VanDerWaalsContact O-N 3.14Å
315	A	91.5	Very high	90.5	Very high	2 Å²	2	27.1 Å²	27.1	2%	0.017	16%	0.155	C	C	.	.	H	α-helix	trans	-62.8	-37.4	176.1	0	0	0	0	0	113.1	I230 L311 T312 N313 T318 T319 F335	I230-A315 HydrophobicContact CG2-CB 3.92Å; L311-A315 WeakPolarHBondContact O-CB 3.37Å; L311-A315 PolarHBondContact O-N 3.34Å; T312-A315 WeakPolarHBondContact O-CB 3.35Å; T312-A315 PolarHBondContact O-N 3.12Å; N313-A315 VanDerWaalsContact C-N 3.27Å; N313-A315 PolarHBondContact O-N 3.27Å; A315-T318 PolarHBondContact O-N 3.41Å; A315-T318 PolarHBondContact O-OG1 2.95Å; A315-T319 PolarHBondContact O-OG1 3Å; A315-F335 HydrophobicContact CB-CE2 4.46Å; A315-F335 VanDerWaalsContact O-CE2 3.29Å; A315-F335 WeakPolarHBondContact O-CE2 3.41Å
316	Y	90.9	Very high	90.2	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-62.4	-45.1	173.5	-64.9	-33.2	0	0	0	111.6	P91 I230 T312 N313 L314 T318 T319 I320 V331 A332 F335	P91-Y316 HydrophobicContact CB-CD2 4.28Å; P91-Y316 HydrophobicContact CB-CE2 4.47Å; P91-Y316 HydrophobicContact CG-CD2 4.2Å; P91-Y316 HydrophobicContact CG-CE2 3.94Å; I230-Y316 HydrophobicContact CD1-CE1 4.24Å; I230-Y316 HydrophobicContact CG2-CD1 4.31Å; I230-Y316 HydrophobicContact CG2-CE1 3.86Å; T312-Y316 HydrophobicContact CG2-CD2 4.48Å; T312-Y316 HydrophobicContact CG2-CE1 4.44Å; T312-Y316 HydrophobicContact CG2-CE2 3.8Å; T312-Y316 PolarHBondContact O-N 3.46Å; N313-Y316 PolarHBondContact O-N 3.08Å; N313-Y316 VanDerWaalsContact O-N 3.11Å; L314-Y316 PolarHBondContact O-N 2.69Å; Y316-T318 VanDerWaalsContact C-N 3.31Å; Y316-T318 PolarHBondContact O-N 2.94Å; Y316-T319 PolarHBondContact O-N 3.12Å; Y316-I320 PolarHBondContact O-N 2.74Å; Y316-V331 HydrophobicContact CD1-CG1 4.03Å; Y316-V331 HydrophobicContact CD2-CG1 3.94Å; Y316-V331 HydrophobicContact CE1-CG1 4.35Å; Y316-V331 HydrophobicContact CE2-CG1 4.26Å; Y316-V331 HydrophobicContact CG-CG1 3.83Å; Y316-A332 HydrophobicContact CE1-CB 4.31Å; Y316-A332 WeakPolarHBondContact OH-CB 3.08Å; Y316-F335 HydrophobicContact CD1-CB 4.13Å; Y316-F335 AromaticContact CD1-CD2 3.95Å; Y316-F335 HydrophobicContact CD1-CD2 3.95Å; Y316-F335 HydrophobicContact CD1-CG 4.14Å; Y316-F335 HydrophobicContact CE1-CB 4.15Å; Y316-F335 HydrophobicContact CE1-CG 4.29Å
317	F	89.5	Confident	89.8	Confident	8 Å²	8	33.8 Å²	33.8	4%	0.035	20%	0.196	C	C	.	.	H	α-helix	trans	-70.6	-18.6	-178.3	-66.5	-56.7	0	0	0	115.1	Y95 V101 L105 L247 N313 L314 T319 M325	Y95-F317 AromaticContact CD2-CE1 3.76Å; Y95-F317 HydrophobicContact CD2-CE1 3.76Å; Y95-F317 AromaticContact CD2-CZ 3.97Å; Y95-F317 HydrophobicContact CD2-CZ 3.97Å; Y95-F317 HydrophobicContact CE2-CE1 4.27Å; Y95-F317 HydrophobicContact CG-CE1 4.36Å; V101-F317 HydrophobicContact CB-CD1 4.32Å; V101-F317 HydrophobicContact CB-CE1 4.4Å; V101-F317 HydrophobicContact CB-CG 4.43Å; V101-F317 HydrophobicContact CG1-CB 3.86Å; V101-F317 HydrophobicContact CG1-CD1 3.87Å; V101-F317 HydrophobicContact CG1-CD2 3.57Å; V101-F317 HydrophobicContact CG1-CE1 4.23Å; V101-F317 HydrophobicContact CG1-CE2 3.99Å; V101-F317 HydrophobicContact CG1-CG 3.51Å; V101-F317 HydrophobicContact CG1-CZ 4.31Å; V101-F317 HydrophobicContact CG2-CD1 3.72Å; V101-F317 HydrophobicContact CG2-CE1 3.89Å; V101-F317 HydrophobicContact CG2-CG 4.23Å; L105-F317 HydrophobicContact CD2-CD2 4.21Å; L105-F317 HydrophobicContact CD2-CE2 4.15Å; L105-F317 HydrophobicContact CG-CD2 4.42Å; L105-F317 HydrophobicContact CG-CE2 4.29Å; L247-F317 HydrophobicContact CD2-CB 4.07Å; N313-F317 HydrophobicContact CB-CD2 4.49Å; N313-F317 HydrophobicContact CB-CE2 4.19Å; N313-F317 WeakPolarHBondContact O-CD2 3.41Å; N313-F317 WeakPolarHBondContact O-CG 3.45Å; N313-F317 PolarHBondContact O-N 3.01Å; L314-F317 PolarHBondContact O-N 2.93Å; F317-T319 PolarHBondContact O-N 3.25Å; F317-M325 HydrophobicContact CD1-CE 4.25Å; F317-M325 HydrophobicContact CE1-CE 3.29Å; F317-M325 HydrophobicContact CE1-SD 3.98Å; F317-M325 HydrophobicContact CZ-CE 3.8Å; F317-M325 HydrophobicContact CZ-SD 4.46Å
318	T	86.8	Confident	89.4	Confident	5 Å²	5	31.9 Å²	31.9	3%	0.031	18%	0.18	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.4	-13.3	173.7	61.4	0	0	0	0	113.1	I238 L247 L314 A315 Y316	I238-T318 HydrophobicContact CD1-CG2 3.82Å; I238-T318 HydrophobicContact CG1-CG2 3.46Å; I238-T318 VanDerWaalsContact CG1-CG2 3.46Å; L247-T318 HydrophobicContact CD1-CG2 3.41Å; L247-T318 VanDerWaalsContact CD1-CG2 3.41Å; L314-T318 WeakPolarHBondContact O-CG2 3.4Å; L314-T318 PolarHBondContact O-N 2.8Å; L314-T318 VanDerWaalsContact O-N 3.14Å; A315-T318 PolarHBondContact O-N 3.41Å; A315-T318 PolarHBondContact O-OG1 2.95Å; Y316-T318 VanDerWaalsContact C-N 3.31Å; Y316-T318 PolarHBondContact O-N 2.94Å
319	T	84.1	Confident	88.8	Confident	34 Å²	34	34.3 Å²	34.3	21%	0.209	19%	0.189	C	C	.	.	T	Hydrogen-bonded Turn	trans	-125.4	-49.5	-167.6	-54.4	0	0	0	0	112.1	A315 Y316 F317 F335 Y338 H339	A315-T319 PolarHBondContact O-OG1 3Å; Y316-T319 PolarHBondContact O-N 3.12Å; F317-T319 PolarHBondContact O-N 3.25Å; T319-F335 HydrophobicContact CG2-CD2 4.15Å; T319-F335 HydrophobicContact CG2-CE2 4.34Å; T319-F335 WeakPolarHBondContact OG1-CE2 3.43Å; T319-Y338 HydrophobicContact CG2-CD2 4.35Å; T319-Y338 HydrophobicContact CG2-CG 4.24Å; T319-H339 WeakPolarHBondContact CG2-CE1 3.31Å; T319-H339 PolarHBondContact OG1-CE1 3.14Å
320	I	86.2	Confident	88.4	Confident	5 Å²	5	34.3 Å²	34.3	3%	0.026	19%	0.189	C	C	.	.	S	Bend	trans	-94.4	126.5	-173.4	-58.6	176.3	0	0	0	107.2	Y316 D324 M325 V331 D334 F335 Y338	Y316-I320 PolarHBondContact O-N 2.74Å; I320-D324 HydrophobicContact CG2-CB 3.68Å; I320-M325 HydrophobicContact CG2-CB 3.99Å; I320-V331 HydrophobicContact CD1-CG1 3.58Å; I320-V331 WeakPolarHBondContact CD1-O 3.31Å; I320-D334 HydrophobicContact CD1-CB 4.26Å; I320-F335 HydrophobicContact CD1-CB 3.94Å; I320-Y338 HydrophobicContact CG1-CD2 4.47Å
321	S	87.3	Confident	88.1	Confident	42 Å²	42	32.8 Å²	32.8	29%	0.294	18%	0.18	S	C	.	.			trans	-64.2	153	174.7	76.3	0	0	0	0	110.1	E323 D324 M325	S321-E323 PolarHBondContact O-N 3.21Å; S321-D324 PolarHBondContact O-N 3.41Å; S321-D324 WeakPolarHBondContact OG-CB 3.47Å; S321-D324 PolarHBondContact OG-N 2.6Å; S321-D324 PolarHBondContact OG-OD2 2.98Å; S321-M325 PolarHBondContact O-N 2.87Å
322	P	83.9	Confident	87.8	Confident	19 Å²	19	30.1 Å²	30.1	12%	0.123	17%	0.166	C	C	.	.	H	α-helix	trans	-63.7	-29.6	-178.1	-15.4	26.2	0	0	0	113.7	Y95 V101 E246 M325 L326	Y95-P322 HydrophobicContact CE1-CB 3.64Å; Y95-P322 HydrophobicContact CE2-CB 4.09Å; Y95-P322 WeakPolarHBondContact OH-CB 3.31Å; V101-P322 HydrophobicContact CG2-CG 4.49Å; E246-P322 HydrophobicContact CG-CG 4.31Å; P322-M325 PolarHBondContact O-N 2.87Å; P322-L326 WeakPolarHBondContact O-CG 3.44Å; P322-L326 PolarHBondContact O-N 3.33Å
323	E	85.6	Confident	87.6	Confident	161 Å²	161	30.3 Å²	30.3	75%	0.752	17%	0.167	S	C	*	.	H	α-helix	trans	-67.8	-43.1	174.3	-63.4	177.9	-178.7	0	0	111.9	S321 M325 L326 S327	S321-E323 PolarHBondContact O-N 3.21Å; E323-M325 VanDerWaalsContact C-N 3.32Å; E323-M325 PolarHBondContact O-N 3.22Å; E323-L326 PolarHBondContact O-N 3.37Å; E323-S327 PolarHBondContact O-N 2.98Å; E323-S327 PolarHBondContact O-OG 2.84Å
324	D	86.8	Confident	87.3	Confident	60 Å²	60	31.6 Å²	31.6	32%	0.321	17%	0.174	S	C	.	.	H	α-helix	trans	-64.6	-38	175.5	-66.5	-33.3	0	0	0	111.2	I320 S321 L326 S327 S328 Y338	I320-D324 HydrophobicContact CG2-CB 3.68Å; S321-D324 PolarHBondContact O-N 3.41Å; S321-D324 WeakPolarHBondContact OG-CB 3.47Å; S321-D324 PolarHBondContact OG-N 2.6Å; S321-D324 PolarHBondContact OG-OD2 2.98Å; D324-L326 VanDerWaalsContact C-N 3.32Å; D324-L326 PolarHBondContact O-N 3.48Å; D324-S327 WeakPolarHBondContact CA-OG 3.38Å; D324-S327 PolarHBondContact O-N 3.12Å; D324-S327 PolarHBondContact O-OG 3.46Å; D324-S327 VanDerWaalsContact O-OG 3.08Å; D324-S328 VanDerWaalsContact O-CB 3.25Å; D324-S328 WeakPolarHBondContact O-CB 3.4Å; D324-S328 PolarHBondContact O-N 3.45Å; D324-Y338 PolarHBondContact OD2-OH 3.41Å
325	M	88.8	Confident	87.2	Confident	1 Å²	1	29.7 Å²	29.7	1%	0.005	16%	0.164	C	C	.	.	H	α-helix	trans	-67.1	-33.6	179.2	-165.7	172.4	65.7	0	0	112.8	P91 T92 Y95 F317 I320 S321 P322 E323 V331	P91-M325 HydrophobicContact CB-SD 4.46Å; T92-M325 VanDerWaalsContact CG2-O 3.27Å; T92-M325 WeakPolarHBondContact CG2-O 3.35Å; T92-M325 PolarHBondContact OG1-O 2.97Å; Y95-M325 HydrophobicContact CD1-CE 3.54Å; Y95-M325 HydrophobicContact CD2-CE 3.79Å; Y95-M325 HydrophobicContact CE1-CE 4.46Å; Y95-M325 HydrophobicContact CG-CE 3.18Å; F317-M325 HydrophobicContact CD1-CE 4.25Å; F317-M325 HydrophobicContact CE1-CE 3.29Å; F317-M325 HydrophobicContact CE1-SD 3.98Å; F317-M325 HydrophobicContact CZ-CE 3.8Å; F317-M325 HydrophobicContact CZ-SD 4.46Å; I320-M325 HydrophobicContact CG2-CB 3.99Å; S321-M325 PolarHBondContact O-N 2.87Å; P322-M325 PolarHBondContact O-N 2.87Å; E323-M325 VanDerWaalsContact C-N 3.32Å; E323-M325 PolarHBondContact O-N 3.22Å; M325-V331 HydrophobicContact CG-CG1 4.06Å; M325-V331 HydrophobicContact CG-CG2 3.77Å; M325-V331 HydrophobicContact SD-CG1 4.27Å
326	L	87.7	Confident	87	Confident	70 Å²	70	29.6 Å²	29.6	37%	0.366	16%	0.163	S	C	.	.	H	α-helix	trans	-73.8	-31.9	177.3	-74	175.9	0	0	0	113.4	Y95 R96 P322 E323 D324	Y95-L326 HydrophobicContact CD1-CD1 4.22Å; Y95-L326 HydrophobicContact CD1-CD2 3.68Å; Y95-L326 HydrophobicContact CD1-CG 3.75Å; Y95-L326 HydrophobicContact CE1-CD1 3.82Å; Y95-L326 HydrophobicContact CE1-CD2 4.16Å; Y95-L326 HydrophobicContact CE1-CG 3.8Å; R96-L326 HydrophobicContact CB-CD2 3.69Å; R96-L326 HydrophobicContact CG-CD2 4.21Å; P322-L326 WeakPolarHBondContact O-CG 3.44Å; P322-L326 PolarHBondContact O-N 3.33Å; E323-L326 PolarHBondContact O-N 3.37Å; D324-L326 VanDerWaalsContact C-N 3.32Å; D324-L326 PolarHBondContact O-N 3.48Å
327	S	86.3	Confident	86.8	Confident	92 Å²	92	33.3 Å²	33.3	64%	0.643	18%	0.183	S	C	*	.	H	α-helix	trans	-84.9	-16.7	176.6	60.4	0	0	0	0	113.1	E323 D324	E323-S327 PolarHBondContact O-N 2.98Å; E323-S327 PolarHBondContact O-OG 2.84Å; D324-S327 WeakPolarHBondContact CA-OG 3.38Å; D324-S327 PolarHBondContact O-N 3.12Å; D324-S327 PolarHBondContact O-OG 3.46Å; D324-S327 VanDerWaalsContact O-OG 3.08Å
328	S	85.6	Confident	86.6	Confident	9 Å²	9	39.5 Å²	39.5	6%	0.063	21%	0.207	C	C	.	.			trans	-78.7	129.9	178.1	-176.3	0	0	0	0	113.5	D324 A330 V331 D334	D324-S328 VanDerWaalsContact O-CB 3.25Å; D324-S328 WeakPolarHBondContact O-CB 3.4Å; D324-S328 PolarHBondContact O-N 3.45Å; S328-A330 VanDerWaalsContact OG-C 3.24Å; S328-A330 PolarHBondContact OG-N 3.48Å; S328-A330 VanDerWaalsContact OG-N 3.07Å; S328-V331 PolarHBondContact OG-N 2.96Å; S328-D334 WeakPolarHBondContact CB-OD2 3.22Å; S328-D334 PolarHBondContact OG-OD2 3.15Å
329	E	81.9	Confident	86.5	Confident	82 Å²	82	41.6 Å²	41.6	38%	0.383	22%	0.217	S	C	.	.	S	Bend	trans	-84.7	-14.3	167.8	-62.2	175.9	158.1	0	0	112.6	T173 V185	T173-E329 HydrophobicContact CG2-CB 3.93Å; V185-E329 PolarHBondContact N-OE2 3.35Å
330	A	86.8	Confident	86.4	Confident	0 Å²	0	41.7 Å²	41.7	0%	0	22%	0.216	C	C	.	.			trans	-148.7	70.1	-172.2	0	0	0	0	0	111.6	Y174 K177 S328 A332 V333 D334	Y174-A330 HydrophobicContact CD1-CB 4.21Å; Y174-A330 HydrophobicContact CD2-CB 4.23Å; Y174-A330 HydrophobicContact CE1-CB 3.86Å; Y174-A330 HydrophobicContact CE2-CB 3.89Å; Y174-A330 HydrophobicContact CG-CB 4.39Å; Y174-A330 WeakPolarHBondContact OH-CA 3.2Å; K177-A330 HydrophobicContact CB-CB 4.25Å; K177-A330 HydrophobicContact CG-CB 4.02Å; S328-A330 VanDerWaalsContact OG-C 3.24Å; S328-A330 PolarHBondContact OG-N 3.48Å; S328-A330 VanDerWaalsContact OG-N 3.07Å; A330-A332 PolarHBondContact O-N 3.28Å; A330-V333 HydrophobicContact CB-CB 4.19Å; A330-V333 HydrophobicContact CB-CG2 4Å; A330-V333 WeakPolarHBondContact O-CB 3.49Å; A330-V333 PolarHBondContact O-N 3.36Å; A330-D334 PolarHBondContact O-N 2.96Å
331	V	88.4	Confident	86.2	Confident	1 Å²	1	43.5 Å²	43.5	1%	0.006	24%	0.236	C	C	.	.	H	α-helix	trans	-50.4	-40.1	-172.7	-177.9	0	0	0	0	113.2	T92 Y316 I320 M325 S328 V333 D334 F335	T92-V331 WeakPolarHBondContact OG1-CG2 3.25Å; Y316-V331 HydrophobicContact CD1-CG1 4.03Å; Y316-V331 HydrophobicContact CD2-CG1 3.94Å; Y316-V331 HydrophobicContact CE1-CG1 4.35Å; Y316-V331 HydrophobicContact CE2-CG1 4.26Å; Y316-V331 HydrophobicContact CG-CG1 3.83Å; I320-V331 HydrophobicContact CD1-CG1 3.58Å; I320-V331 WeakPolarHBondContact CD1-O 3.31Å; M325-V331 HydrophobicContact CG-CG1 4.06Å; M325-V331 HydrophobicContact CG-CG2 3.77Å; M325-V331 HydrophobicContact SD-CG1 4.27Å; S328-V331 PolarHBondContact OG-N 2.96Å; V331-V333 VanDerWaalsContact C-N 3.35Å; V331-V333 PolarHBondContact O-N 3.48Å; V331-D334 PolarHBondContact O-N 2.91Å; V331-F335 PolarHBondContact O-N 3.25Å
332	A	88.1	Confident	85.9	Confident	0 Å²	0	47.2 Å²	47.2	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-67	-34	179.5	0	0	0	0	0	113.1	F88 Y174 I230 Y316 A330 F335 G336 I347 V351	F88-A332 HydrophobicContact CD1-CB 3.81Å; F88-A332 HydrophobicContact CE1-CB 4.29Å; Y174-A332 HydrophobicContact CE1-CB 4.05Å; I230-A332 HydrophobicContact CD1-CB 4.35Å; Y316-A332 HydrophobicContact CE1-CB 4.31Å; Y316-A332 WeakPolarHBondContact OH-CB 3.08Å; A330-A332 PolarHBondContact O-N 3.28Å; A332-F335 WeakPolarHBondContact O-CB 3.27Å; A332-F335 PolarHBondContact O-N 3.31Å; A332-G336 PolarHBondContact O-N 2.98Å; A332-I347 HydrophobicContact CB-CG2 3.8Å; A332-I347 VanDerWaalsContact O-CG2 3.28Å; A332-I347 WeakPolarHBondContact O-CG2 3.32Å; A332-V351 HydrophobicContact CB-CG2 4.34Å
333	V	87.6	Confident	85.7	Confident	3 Å²	3	51 Å²	51	2%	0.018	28%	0.276	C	S	.	.	H	α-helix	trans	-66.6	-42.7	176.1	178.2	0	0	0	0	109.8	Y174 K177 A330 V331 F335 G336 N337 P348	Y174-V333 HydrophobicContact CD1-CG2 3.59Å; Y174-V333 HydrophobicContact CE1-CG2 3.73Å; K177-V333 HydrophobicContact CG-CG1 4.33Å; A330-V333 HydrophobicContact CB-CB 4.19Å; A330-V333 HydrophobicContact CB-CG2 4Å; A330-V333 WeakPolarHBondContact O-CB 3.49Å; A330-V333 PolarHBondContact O-N 3.36Å; V331-V333 VanDerWaalsContact C-N 3.35Å; V331-V333 PolarHBondContact O-N 3.48Å; V333-F335 PolarHBondContact O-N 2.98Å; V333-G336 CarbonylContact O-C 3.55Å; V333-G336 WeakPolarHBondContact O-CA 3.42Å; V333-G336 PolarHBondContact O-N 3.12Å; V333-G336 VanDerWaalsContact O-N 3.1Å; V333-N337 PolarHBondContact O-N 3.46Å; V333-N337 PolarHBondContact O-ND2 2.97Å; V333-P348 HydrophobicContact CG2-CB 3.98Å
334	D	88.2	Confident	85.4	Confident	28 Å²	28	43.9 Å²	43.9	15%	0.15	25%	0.245	C	C	.	.	H	α-helix	trans	-64.5	-42.1	177.3	-63.1	-25.9	0	0	0	111.4	I320 S328 A330 V331 G336 N337 Y338	I320-D334 HydrophobicContact CD1-CB 4.26Å; S328-D334 WeakPolarHBondContact CB-OD2 3.22Å; S328-D334 PolarHBondContact OG-OD2 3.15Å; A330-D334 PolarHBondContact O-N 2.96Å; V331-D334 PolarHBondContact O-N 2.91Å; D334-G336 PolarHBondContact O-N 3.23Å; D334-N337 PolarHBondContact O-N 3.46Å; D334-N337 VanDerWaalsContact O-N 3.12Å; D334-Y338 WeakPolarHBondContact O-CD2 3.47Å; D334-Y338 PolarHBondContact O-N 3.45Å
335	F	88.8	Confident	85.2	Confident	1 Å²	1	48.3 Å²	48.3	0%	0.004	26%	0.257	C	S	.	.	H	α-helix	trans	-55.3	-42.5	171.6	-176.2	-90	0	0	0	111.8	I230 I233 A315 Y316 T319 I320 V331 A332 V333 H339	I230-F335 HydrophobicContact CB-CE1 4.24Å; I230-F335 HydrophobicContact CG1-CD1 4.13Å; I230-F335 HydrophobicContact CG1-CE1 4.19Å; I230-F335 HydrophobicContact CG2-CD1 4.29Å; I230-F335 HydrophobicContact CG2-CE1 4.02Å; I230-F335 HydrophobicContact CG2-CZ 4.16Å; I233-F335 HydrophobicContact CB-CE1 4Å; I233-F335 HydrophobicContact CB-CZ 3.88Å; I233-F335 HydrophobicContact CD1-CE1 4.29Å; I233-F335 HydrophobicContact CG2-CE1 3.87Å; I233-F335 HydrophobicContact CG2-CZ 3.59Å; A315-F335 HydrophobicContact CB-CE2 4.46Å; A315-F335 VanDerWaalsContact O-CE2 3.29Å; A315-F335 WeakPolarHBondContact O-CE2 3.41Å; Y316-F335 HydrophobicContact CD1-CB 4.13Å; Y316-F335 AromaticContact CD1-CD2 3.95Å; Y316-F335 HydrophobicContact CD1-CD2 3.95Å; Y316-F335 HydrophobicContact CD1-CG 4.14Å; Y316-F335 HydrophobicContact CE1-CB 4.15Å; Y316-F335 HydrophobicContact CE1-CG 4.29Å; T319-F335 HydrophobicContact CG2-CD2 4.15Å; T319-F335 HydrophobicContact CG2-CE2 4.34Å; T319-F335 WeakPolarHBondContact OG1-CE2 3.43Å; I320-F335 HydrophobicContact CD1-CB 3.94Å; V331-F335 PolarHBondContact O-N 3.25Å; A332-F335 WeakPolarHBondContact O-CB 3.27Å; A332-F335 PolarHBondContact O-N 3.31Å; V333-F335 PolarHBondContact O-N 2.98Å; F335-H339 AromaticContact CE1-ND1 3.97Å; F335-H339 AromaticContact CE2-CE1 3.59Å; F335-H339 AromaticContact CZ-CE1 3.7Å; F335-H339 AromaticContact CZ-ND1 3.91Å; F335-H339 PolarHBondContact O-ND1 3.36Å
336	G	87	Confident	84.9	Confident	0 Å²	0	50.1 Å²	50.1	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-64.2	-43.9	175.5	0	0	0	0	0	112.9	A332 V333 D334 Y338 H339 L340	A332-G336 PolarHBondContact O-N 2.98Å; V333-G336 CarbonylContact O-C 3.55Å; V333-G336 WeakPolarHBondContact O-CA 3.42Å; V333-G336 PolarHBondContact O-N 3.12Å; V333-G336 VanDerWaalsContact O-N 3.1Å; D334-G336 PolarHBondContact O-N 3.23Å; G336-Y338 VanDerWaalsContact C-N 3.33Å; G336-Y338 PolarHBondContact O-N 2.96Å; G336-H339 PolarHBondContact O-N 3.19Å; G336-L340 WeakPolarHBondContact O-CB 3.25Å; G336-L340 PolarHBondContact O-N 3.03Å
337	N	87.2	Confident	84.8	Confident	78 Å²	78	46.9 Å²	46.9	42%	0.417	25%	0.249	S	C	.	.	H	α-helix	trans	-61.3	-39.7	178.9	-72.5	-28.4	0	0	0	112.1	V333 D334 H339 A344	V333-N337 PolarHBondContact O-N 3.46Å; V333-N337 PolarHBondContact O-ND2 2.97Å; D334-N337 PolarHBondContact O-N 3.46Å; D334-N337 VanDerWaalsContact O-N 3.12Å; N337-H339 VanDerWaalsContact C-N 3.31Å; N337-H339 PolarHBondContact O-N 3.21Å; N337-A344 VanDerWaalsContact OD1-CB 3.3Å; N337-A344 WeakPolarHBondContact OD1-CB 3.28Å
338	Y	85.8	Confident	84.8	Confident	139 Å²	139	43 Å²	43	55%	0.545	22%	0.222	S	C	.	.	H	α-helix	trans	-66.1	-27.9	178	-82.8	-67.9	0	0	0	114.1	T319 I320 D324 D334 G336	T319-Y338 HydrophobicContact CG2-CD2 4.35Å; T319-Y338 HydrophobicContact CG2-CG 4.24Å; I320-Y338 HydrophobicContact CG1-CD2 4.47Å; D324-Y338 PolarHBondContact OD2-OH 3.41Å; D334-Y338 WeakPolarHBondContact O-CD2 3.47Å; D334-Y338 PolarHBondContact O-N 3.45Å; G336-Y338 VanDerWaalsContact C-N 3.33Å; G336-Y338 PolarHBondContact O-N 2.96Å
339	H	85.3	Confident	84.8	Confident	48 Å²	48	45.8 Å²	45.8	22%	0.222	24%	0.239	C	C	.	.	H	α-helix	trans	-117	-40.5	-169.4	-68.6	103.1	0	0	0	115.8	I233 K237 T319 F335 G336 N337	I233-H339 HydrophobicContact CG2-CB 4.13Å; I233-H339 WeakPolarHBondContact CG2-CD2 2.97Å; I233-H339 WeakPolarHBondContact CG2-NE2 3.27Å; K237-H339 WeakPolarHBondContact CE-CD2 3.18Å; K237-H339 WeakPolarHBondContact CE-NE2 3.48Å; K237-H339 VanDerWaalsContact CG-NE2 3.35Å; K237-H339 WeakPolarHBondContact CG-NE2 3.08Å; T319-H339 WeakPolarHBondContact CG2-CE1 3.31Å; T319-H339 PolarHBondContact OG1-CE1 3.14Å; F335-H339 AromaticContact CE1-ND1 3.97Å; F335-H339 AromaticContact CE2-CE1 3.59Å; F335-H339 AromaticContact CZ-CE1 3.7Å; F335-H339 AromaticContact CZ-ND1 3.91Å; F335-H339 PolarHBondContact O-ND1 3.36Å; G336-H339 PolarHBondContact O-N 3.19Å; N337-H339 VanDerWaalsContact C-N 3.31Å; N337-H339 PolarHBondContact O-N 3.21Å
340	L	80.9	Confident	84.9	Confident	36 Å²	36	44.6 Å²	44.6	19%	0.188	23%	0.232	C	C	.	.	H	α-helix	trans	-91.4	-11.4	-166.9	-63.7	169.9	0	0	0	112	L229 I233 G336 P342 M343 I347	L229-L340 HydrophobicContact CD2-CD1 4.2Å; L229-L340 HydrophobicContact CD2-CD2 4.46Å; I233-L340 HydrophobicContact CD1-CD2 3.99Å; I233-L340 HydrophobicContact CD1-CG 4.48Å; G336-L340 WeakPolarHBondContact O-CB 3.25Å; G336-L340 PolarHBondContact O-N 3.03Å; L340-P342 WeakPolarHBondContact O-CD 3.44Å; L340-P342 VanDerWaalsContact O-N 3.12Å; L340-M343 HydrophobicContact CB-CB 4.16Å; L340-M343 PolarHBondContact O-N 3.37Å; L340-I347 HydrophobicContact CD1-CD1 3.98Å; L340-I347 HydrophobicContact CD1-CG1 3.67Å
341	G	82.8	Confident	84.8	Confident	44 Å²	44	44.6 Å²	44.6	45%	0.454	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	49.6	-116.3	178.7	0	0	0	0	0	111.3	M343 A344	G341-M343 PolarHBondContact O-N 3.19Å; G341-M343 VanDerWaalsContact O-N 3.08Å; G341-A344 VanDerWaalsContact O-CB 3.27Å; G341-A344 WeakPolarHBondContact O-CB 3.26Å; G341-A344 PolarHBondContact O-N 3Å
342	P	80.6	Confident	84.7	Confident	119 Å²	119	44.8 Å²	44.8	77%	0.773	24%	0.235	S	C	*	.	G	3₁₀ helix	trans	-58.4	-21.3	177.4	-22.9	33.4	0	0	0	115.2	L340	L340-P342 WeakPolarHBondContact O-CD 3.44Å; L340-P342 VanDerWaalsContact O-N 3.12Å
343	M	78.8	Confident	84.5	Confident	99 Å²	99	46.9 Å²	46.9	49%	0.488	25%	0.246	S	C	.	.	G	3₁₀ helix	trans	-94.8	9.7	180	-61.1	-59.4	164.9	0	0	113.1	L340 G341 W345 I346	L340-M343 HydrophobicContact CB-CB 4.16Å; L340-M343 PolarHBondContact O-N 3.37Å; G341-M343 PolarHBondContact O-N 3.19Å; G341-M343 VanDerWaalsContact O-N 3.08Å; M343-W345 PolarHBondContact O-N 2.94Å; M343-W345 VanDerWaalsContact O-N 3.12Å; M343-I346 HydrophobicContact CB-CD1 3.91Å; M343-I346 HydrophobicContact CB-CG1 4.48Å; M343-I346 WeakPolarHBondContact O-CB 3.41Å; M343-I346 WeakPolarHBondContact O-CG1 3.21Å; M343-I346 PolarHBondContact O-N 3.21Å; M343-I346 VanDerWaalsContact O-N 3.09Å; M343-I346 HydrophobicContact SD-CD1 4.46Å
344	A	80.2	Confident	84.4	Confident	11 Å²	11	46.9 Å²	46.9	9%	0.091	25%	0.246	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.3	-24.6	179.6	0	0	0	0	0	113.5	N337 G341 I346 I347 P348	N337-A344 VanDerWaalsContact OD1-CB 3.3Å; N337-A344 WeakPolarHBondContact OD1-CB 3.28Å; G341-A344 VanDerWaalsContact O-CB 3.27Å; G341-A344 WeakPolarHBondContact O-CB 3.26Å; G341-A344 PolarHBondContact O-N 3Å; A344-I346 PolarHBondContact O-N 3.09Å; A344-I346 VanDerWaalsContact O-N 3.15Å; A344-I347 PolarHBondContact O-N 2.95Å; A344-P348 WeakPolarHBondContact O-CD 3.3Å
345	W	81.6	Confident	84.3	Confident	154 Å²	154	45.6 Å²	45.6	58%	0.583	24%	0.239	S	C	*	.	T	Hydrogen-bonded Turn	trans	-61.6	-18.8	175.8	66.8	-93.7	0	0	0	114.1	M343 I347 P348 V349	M343-W345 PolarHBondContact O-N 2.94Å; M343-W345 VanDerWaalsContact O-N 3.12Å; W345-I347 PolarHBondContact O-N 3.03Å; W345-P348 WeakPolarHBondContact O-CD 3.33Å; W345-P348 WeakPolarHBondContact O-CG 3.44Å; W345-V349 HydrophobicContact CE3-CG2 4.03Å; W345-V349 HydrophobicContact CZ3-CG2 4.47Å; W345-V349 VanDerWaalsContact O-CG2 3.3Å; W345-V349 WeakPolarHBondContact O-CG2 3.42Å; W345-V349 PolarHBondContact O-N 3.31Å
346	I	83.8	Confident	84.1	Confident	39 Å²	39	47.3 Å²	47.3	20%	0.2	25%	0.246	C	C	.	.	H	α-helix	trans	-64.5	-40.7	179.7	-66.3	178.1	0	0	0	111.4	M343 A344 V349 F350	M343-I346 HydrophobicContact CB-CD1 3.91Å; M343-I346 HydrophobicContact CB-CG1 4.48Å; M343-I346 WeakPolarHBondContact O-CB 3.41Å; M343-I346 WeakPolarHBondContact O-CG1 3.21Å; M343-I346 PolarHBondContact O-N 3.21Å; M343-I346 VanDerWaalsContact O-N 3.09Å; M343-I346 HydrophobicContact SD-CD1 4.46Å; A344-I346 PolarHBondContact O-N 3.09Å; A344-I346 VanDerWaalsContact O-N 3.15Å; I346-V349 PolarHBondContact O-N 2.82Å; I346-F350 HydrophobicContact CG2-CD2 3.48Å; I346-F350 VanDerWaalsContact CG2-CD2 3.48Å; I346-F350 HydrophobicContact CG2-CE2 3.21Å; I346-F350 HydrophobicContact CG2-CG 4.48Å; I346-F350 HydrophobicContact CG2-CZ 4.02Å; I346-F350 PolarHBondContact O-N 3.49Å
347	I	84.8	Confident	83.9	Confident	1 Å²	1	47.7 Å²	47.7	1%	0.005	25%	0.25	C	S	.	.	H	α-helix	trans	-64.4	-55.5	-177.5	-58	-63.5	0	0	0	112.8	L229 I230 A332 L340 A344 W345 V349 F350 V351	L229-I347 HydrophobicContact CD2-CD1 4.1Å; I230-I347 HydrophobicContact CG1-CD1 4.42Å; A332-I347 HydrophobicContact CB-CG2 3.8Å; A332-I347 VanDerWaalsContact O-CG2 3.28Å; A332-I347 WeakPolarHBondContact O-CG2 3.32Å; L340-I347 HydrophobicContact CD1-CD1 3.98Å; L340-I347 HydrophobicContact CD1-CG1 3.67Å; A344-I347 PolarHBondContact O-N 2.95Å; W345-I347 PolarHBondContact O-N 3.03Å; I347-V349 PolarHBondContact O-N 3.43Å; I347-F350 PolarHBondContact O-N 3.27Å; I347-V351 HydrophobicContact CG2-CG2 4.02Å; I347-V351 WeakPolarHBondContact O-CB 3.15Å; I347-V351 VanDerWaalsContact O-CG2 3.31Å; I347-V351 WeakPolarHBondContact O-CG2 3.49Å; I347-V351 PolarHBondContact O-N 2.92Å
348	P	86.6	Confident	83.7	Confident	12 Å²	12	45.5 Å²	45.5	8%	0.078	24%	0.241	C	C	.	.	H	α-helix	trans	-61.2	-32.7	179.4	24	-33.4	0	0	0	112.2	Y174 P178 V333 A344 W345 G352	Y174-P348 WeakPolarHBondContact O-CB 3.3Å; P178-P348 HydrophobicContact CG-CB 3.78Å; P178-P348 HydrophobicContact CG-CG 3.67Å; V333-P348 HydrophobicContact CG2-CB 3.98Å; A344-P348 WeakPolarHBondContact O-CD 3.3Å; W345-P348 WeakPolarHBondContact O-CD 3.33Å; W345-P348 WeakPolarHBondContact O-CG 3.44Å; P348-G352 WeakPolarHBondContact O-CA 3.42Å; P348-G352 PolarHBondContact O-N 3.37Å
349	V	85.9	Confident	83.7	Confident	67 Å²	67	39 Å²	39	41%	0.406	22%	0.216	S	C	.	.	H	α-helix	trans	-62.5	-54.9	173.1	170	0	0	0	0	110.6	W345 I346 I347 V351 G352 L353	W345-V349 HydrophobicContact CE3-CG2 4.03Å; W345-V349 HydrophobicContact CZ3-CG2 4.47Å; W345-V349 VanDerWaalsContact O-CG2 3.3Å; W345-V349 WeakPolarHBondContact O-CG2 3.42Å; W345-V349 PolarHBondContact O-N 3.31Å; I346-V349 PolarHBondContact O-N 2.82Å; I347-V349 PolarHBondContact O-N 3.43Å; V349-V351 PolarHBondContact O-N 3.18Å; V349-G352 PolarHBondContact O-N 3.07Å; V349-L353 HydrophobicContact CG1-CD1 4.18Å; V349-L353 HydrophobicContact CG1-CG 4.41Å; V349-L353 VanDerWaalsContact O-CG 3.27Å; V349-L353 WeakPolarHBondContact O-CG 3.37Å; V349-L353 PolarHBondContact O-N 3.47Å
350	F	84.1	Confident	83.6	Confident	56 Å²	56	37 Å²	37	25%	0.246	21%	0.207	C	C	.	.	H	α-helix	trans	-66.5	-36.9	-178	-69	-34.5	0	0	0	113.6	A222 A226 I346 I347 L353 S354	A222-F350 HydrophobicContact CB-CD1 4Å; A222-F350 HydrophobicContact CB-CE1 4.32Å; A226-F350 HydrophobicContact CB-CB 3.62Å; A226-F350 HydrophobicContact CB-CD2 3.9Å; A226-F350 HydrophobicContact CB-CG 4.14Å; I346-F350 HydrophobicContact CG2-CD2 3.48Å; I346-F350 VanDerWaalsContact CG2-CD2 3.48Å; I346-F350 HydrophobicContact CG2-CE2 3.21Å; I346-F350 HydrophobicContact CG2-CG 4.48Å; I346-F350 HydrophobicContact CG2-CZ 4.02Å; I346-F350 PolarHBondContact O-N 3.49Å; I347-F350 PolarHBondContact O-N 3.27Å; F350-L353 PolarHBondContact O-N 3.04Å; F350-S354 WeakPolarHBondContact O-CB 3.48Å; F350-S354 PolarHBondContact O-N 3.29Å
351	V	85.1	Confident	83.5	Confident	0 Å²	0	35.9 Å²	35.9	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-65.5	-43.9	174.5	177.6	0	0	0	0	110.5	F88 Y174 A332 I347 V349 L353 S354 C355	F88-V351 HydrophobicContact CB-CG1 4.01Å; F88-V351 HydrophobicContact CD1-CG1 4.29Å; F88-V351 HydrophobicContact CD1-CG2 3.72Å; F88-V351 HydrophobicContact CD2-CB 4.43Å; F88-V351 HydrophobicContact CD2-CG1 3.65Å; F88-V351 HydrophobicContact CD2-CG2 4.17Å; F88-V351 HydrophobicContact CE1-CG2 3.64Å; F88-V351 HydrophobicContact CE2-CG1 4.18Å; F88-V351 HydrophobicContact CE2-CG2 4.09Å; F88-V351 HydrophobicContact CG-CG1 3.7Å; F88-V351 HydrophobicContact CG-CG2 4Å; F88-V351 HydrophobicContact CZ-CG2 3.83Å; Y174-V351 HydrophobicContact CD1-CB 3.68Å; Y174-V351 HydrophobicContact CD1-CG1 3.36Å; Y174-V351 HydrophobicContact CD1-CG2 4.15Å; Y174-V351 HydrophobicContact CD2-CG1 4.08Å; Y174-V351 HydrophobicContact CE1-CB 4.03Å; Y174-V351 HydrophobicContact CE1-CG1 3.59Å; Y174-V351 HydrophobicContact CE1-CG2 4.04Å; Y174-V351 HydrophobicContact CE2-CG1 4.28Å; Y174-V351 HydrophobicContact CG-CB 4.28Å; Y174-V351 HydrophobicContact CG-CG1 3.61Å; A332-V351 HydrophobicContact CB-CG2 4.34Å; I347-V351 HydrophobicContact CG2-CG2 4.02Å; I347-V351 WeakPolarHBondContact O-CB 3.15Å; I347-V351 VanDerWaalsContact O-CG2 3.31Å; I347-V351 WeakPolarHBondContact O-CG2 3.49Å; I347-V351 PolarHBondContact O-N 2.92Å; V349-V351 PolarHBondContact O-N 3.18Å; V351-L353 PolarHBondContact O-N 3.37Å; V351-S354 WeakPolarHBondContact O-CB 3.33Å; V351-S354 PolarHBondContact O-N 2.64Å; V351-C355 PolarHBondContact O-N 3Å; V351-C355 PolarHBondContact O-SG 3.23Å
352	G	86.7	Confident	83.4	Confident	6 Å²	6	34.4 Å²	34.4	6%	0.062	19%	0.187	C	C	.	.	H	α-helix	trans	-58.7	-46.8	175.3	0	0	0	0	0	112	F171 P348 V349 S354 C355 F356	F171-G352 VanDerWaalsContact CD2-O 3.31Å; F171-G352 WeakPolarHBondContact CD2-O 3.39Å; P348-G352 WeakPolarHBondContact O-CA 3.42Å; P348-G352 PolarHBondContact O-N 3.37Å; V349-G352 PolarHBondContact O-N 3.07Å; G352-S354 VanDerWaalsContact C-N 3.31Å; G352-S354 PolarHBondContact O-N 3.13Å; G352-C355 PolarHBondContact O-N 2.8Å; G352-F356 WeakPolarHBondContact O-CB 3.41Å; G352-F356 PolarHBondContact O-N 3.37Å
353	L	83.2	Confident	83.5	Confident	44 Å²	44	28.8 Å²	28.8	23%	0.23	15%	0.15	C	C	.	.	H	α-helix	trans	-60.7	-38.9	175.3	-67.7	-175.3	0	0	0	112.3	F218 F219 V349 F350 V351 G357	F218-L353 HydrophobicContact CE1-CD1 4.43Å; F219-L353 HydrophobicContact CD1-CB 3.8Å; F219-L353 HydrophobicContact CD1-CD1 3.98Å; F219-L353 HydrophobicContact CD1-CD2 3.91Å; F219-L353 HydrophobicContact CD1-CG 4.09Å; F219-L353 HydrophobicContact CE1-CB 4.2Å; F219-L353 HydrophobicContact CE1-CD1 3.97Å; F219-L353 HydrophobicContact CE1-CD2 3.39Å; F219-L353 HydrophobicContact CE1-CG 4.02Å; F219-L353 HydrophobicContact CE2-CD2 4.5Å; F219-L353 HydrophobicContact CG-CB 4.22Å; F219-L353 HydrophobicContact CZ-CD2 3.72Å; V349-L353 HydrophobicContact CG1-CD1 4.18Å; V349-L353 HydrophobicContact CG1-CG 4.41Å; V349-L353 VanDerWaalsContact O-CG 3.27Å; V349-L353 WeakPolarHBondContact O-CG 3.37Å; V349-L353 PolarHBondContact O-N 3.47Å; F350-L353 PolarHBondContact O-N 3.04Å; V351-L353 PolarHBondContact O-N 3.37Å; L353-G357 PolarHBondContact O-N 3.15Å
354	S	85.3	Confident	83.3	Confident	3 Å²	3	27 Å²	27	2%	0.021	14%	0.14	C	C	.	.	H	α-helix	trans	-60.9	-49.9	174.9	-171.6	0	0	0	0	111.6	F350 V351 G352 F356 G357 S358	F350-S354 WeakPolarHBondContact O-CB 3.48Å; F350-S354 PolarHBondContact O-N 3.29Å; V351-S354 WeakPolarHBondContact O-CB 3.33Å; V351-S354 PolarHBondContact O-N 2.64Å; G352-S354 VanDerWaalsContact C-N 3.31Å; G352-S354 PolarHBondContact O-N 3.13Å; S354-F356 PolarHBondContact O-N 3.12Å; S354-G357 PolarHBondContact O-N 2.8Å; S354-S358 PolarHBondContact O-N 3.33Å; S354-S358 PolarHBondContact O-OG 3.1Å
355	C	86.9	Confident	83	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-62.3	-44	179.5	-60.3	0	0	0	0	111.5	S85 V167 F171 V351 G352 G357 S358 V359	S85-C355 WeakPolarHBondContact CB-SG 3.49Å; V167-C355 HydrophobicContact CG1-CB 3.89Å; V167-C355 WeakPolarHBondContact CG1-O 3.26Å; F171-C355 HydrophobicContact CB-CB 3.66Å; F171-C355 HydrophobicContact CD2-CB 4.5Å; V351-C355 PolarHBondContact O-N 3Å; V351-C355 PolarHBondContact O-SG 3.23Å; G352-C355 PolarHBondContact O-N 2.8Å; C355-G357 PolarHBondContact O-N 3.37Å; C355-S358 PolarHBondContact O-N 2.86Å; C355-V359 PolarHBondContact O-N 3.34Å
356	F	84.5	Confident	83	Confident	37 Å²	37	21.1 Å²	21.1	16%	0.162	12%	0.12	C	C	.	.	H	α-helix	trans	-60	-44.2	177.1	-169.3	-85.4	0	0	0	111.8	F171 L200 L201 V215 F219 G352 S354 V359 N360	F171-F356 HydrophobicContact CD2-CB 4.37Å; F171-F356 HydrophobicContact CE2-CB 4.42Å; F171-F356 HydrophobicContact CE2-CD2 4.35Å; F171-F356 HydrophobicContact CZ-CD2 4.44Å; L200-F356 HydrophobicContact CD2-CE2 3.88Å; L200-F356 HydrophobicContact CD2-CZ 3.71Å; L201-F356 HydrophobicContact CD1-CD1 4.45Å; L201-F356 HydrophobicContact CD1-CD2 4.07Å; L201-F356 HydrophobicContact CD1-CE1 4.49Å; L201-F356 HydrophobicContact CD1-CE2 4.06Å; L201-F356 HydrophobicContact CD1-CG 4.28Å; L201-F356 HydrophobicContact CD1-CZ 4.3Å; L201-F356 HydrophobicContact CD2-CD1 3.88Å; L201-F356 HydrophobicContact CD2-CD2 4.43Å; L201-F356 HydrophobicContact CD2-CE1 3.27Å; L201-F356 HydrophobicContact CD2-CE2 3.87Å; L201-F356 HydrophobicContact CD2-CG 4.45Å; L201-F356 HydrophobicContact CD2-CZ 3.26Å; L201-F356 HydrophobicContact CG-CD2 4.24Å; L201-F356 HydrophobicContact CG-CE1 4.08Å; L201-F356 HydrophobicContact CG-CE2 3.72Å; L201-F356 HydrophobicContact CG-CZ 3.64Å; V215-F356 HydrophobicContact CG1-CE1 4.5Å; F219-F356 HydrophobicContact CD2-CD1 4.12Å; F219-F356 AromaticContact CE2-CD1 3.48Å; F219-F356 HydrophobicContact CE2-CD1 3.48Å; F219-F356 VanDerWaalsContact CE2-CD1 3.48Å; F219-F356 AromaticContact CE2-CE1 3.95Å; F219-F356 HydrophobicContact CE2-CE1 3.95Å; F219-F356 HydrophobicContact CE2-CG 4.44Å; F219-F356 HydrophobicContact CZ-CD1 4.38Å; G352-F356 WeakPolarHBondContact O-CB 3.41Å; G352-F356 PolarHBondContact O-N 3.37Å; S354-F356 PolarHBondContact O-N 3.12Å; F356-V359 PolarHBondContact O-N 3.39Å; F356-N360 WeakPolarHBondContact O-CB 3.46Å; F356-N360 PolarHBondContact O-N 3.47Å; F356-N360 VanDerWaalsContact O-N 3.12Å
357	G	81.5	Confident	82.6	Confident	8 Å²	8	19.7 Å²	19.7	8%	0.082	11%	0.114	C	C	.	.	H	α-helix	trans	-62.6	-39.8	174.6	0	0	0	0	0	113.3	L353 S354 C355 N360 G361	L353-G357 PolarHBondContact O-N 3.15Å; S354-G357 PolarHBondContact O-N 2.8Å; C355-G357 PolarHBondContact O-N 3.37Å; G357-N360 PolarHBondContact O-N 3.34Å; G357-G361 PolarHBondContact O-N 3.3Å
358	S	83.1	Confident	82.1	Confident	33 Å²	33	24.8 Å²	24.8	23%	0.231	13%	0.133	C	C	.	.	H	α-helix	trans	-65.8	-41.7	177.4	-74.3	0	0	0	0	113	S354 C355 G361 S362	S354-S358 PolarHBondContact O-N 3.33Å; S354-S358 PolarHBondContact O-OG 3.1Å; C355-S358 PolarHBondContact O-N 2.86Å; S358-G361 PolarHBondContact O-N 2.93Å; S358-S362 WeakPolarHBondContact O-CB 3.32Å; S358-S362 PolarHBondContact O-N 2.88Å
359	V	86.5	Confident	81.8	Confident	1 Å²	1	24.7 Å²	24.7	1%	0.006	13%	0.132	C	C	.	.	H	α-helix	trans	-63.6	-44.2	174.7	178.1	0	0	0	0	110.4	V167 A168 L201 C355 F356 G361 S362 L363	V167-V359 HydrophobicContact CB-CG2 3.79Å; V167-V359 HydrophobicContact CG1-CG2 3.59Å; A168-V359 HydrophobicContact CB-CG2 4.2Å; L201-V359 HydrophobicContact CD1-CB 3.59Å; L201-V359 HydrophobicContact CD1-CG1 3.52Å; C355-V359 PolarHBondContact O-N 3.34Å; F356-V359 PolarHBondContact O-N 3.39Å; V359-G361 PolarHBondContact O-N 3.2Å; V359-S362 PolarHBondContact O-N 3.42Å; V359-L363 HydrophobicContact CG1-CD1 4.22Å; V359-L363 HydrophobicContact CG1-CG 4.49Å; V359-L363 WeakPolarHBondContact O-CG 3.29Å; V359-L363 PolarHBondContact O-N 3.32Å
360	N	83.9	Confident	81.6	Confident	6 Å²	6	21.5 Å²	21.5	3%	0.032	11%	0.113	C	C	.	.	H	α-helix	trans	-58.1	-48.1	177.1	-172.4	68.4	0	0	0	112.2	L201 N205 A212 Q216 F356 G357 S362 L363 F364	L201-N360 HydrophobicContact CD2-CB 3.89Å; N205-N360 PolarHBondContact ND2-OD1 2.74Å; A212-N360 PolarHBondContact O-ND2 3.47Å; A212-N360 VanDerWaalsContact O-ND2 3.15Å; Q216-N360 PolarHBondContact OE1-ND2 3.4Å; F356-N360 WeakPolarHBondContact O-CB 3.46Å; F356-N360 PolarHBondContact O-N 3.47Å; F356-N360 VanDerWaalsContact O-N 3.12Å; G357-N360 PolarHBondContact O-N 3.34Å; N360-S362 VanDerWaalsContact C-N 3.32Å; N360-S362 PolarHBondContact O-N 3.44Å; N360-L363 PolarHBondContact O-N 2.75Å; N360-F364 PolarHBondContact O-N 3.42Å
361	G	77.9	Confident	81.2	Confident	14 Å²	14	20.8 Å²	20.8	14%	0.144	11%	0.109	C	C	.	.	H	α-helix	trans	-63.4	-35.9	176.6	0	0	0	0	0	113.2	G357 S358 V359 F364 T365	G357-G361 PolarHBondContact O-N 3.3Å; S358-G361 PolarHBondContact O-N 2.93Å; V359-G361 PolarHBondContact O-N 3.2Å; G361-F364 PolarHBondContact O-N 3.35Å; G361-T365 WeakPolarHBondContact O-CG2 3.2Å; G361-T365 PolarHBondContact O-N 3.21Å; G361-T365 PolarHBondContact O-OG1 3.26Å
362	S	80.9	Confident	80.8	Confident	13 Å²	13	21.6 Å²	21.6	9%	0.091	11%	0.114	C	C	.	.	H	α-helix	trans	-67.2	-41.7	175.4	-174.8	0	0	0	0	112.3	Q164 S358 V359 N360 F364 T365 S366	Q164-S362 VanDerWaalsContact CG-OG 3.25Å; Q164-S362 WeakPolarHBondContact CG-OG 3.34Å; Q164-S362 PolarHBondContact NE2-OG 2.93Å; S358-S362 WeakPolarHBondContact O-CB 3.32Å; S358-S362 PolarHBondContact O-N 2.88Å; V359-S362 PolarHBondContact O-N 3.42Å; N360-S362 VanDerWaalsContact C-N 3.32Å; N360-S362 PolarHBondContact O-N 3.44Å; S362-F364 PolarHBondContact O-N 3.32Å; S362-T365 PolarHBondContact O-N 3.16Å; S362-T365 PolarHBondContact O-OG1 2.87Å; S362-S366 WeakPolarHBondContact O-CB 3.04Å; S362-S366 PolarHBondContact O-N 3.25Å; S362-S366 PolarHBondContact O-OG 2.83Å
363	L	82.1	Confident	80.7	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-61	-44.8	174.5	-73.7	170.3	0	0	0	111.2	L201 V359 N360 S366 S367 L397	L201-L363 HydrophobicContact CB-CD1 3.85Å; V359-L363 HydrophobicContact CG1-CD1 4.22Å; V359-L363 HydrophobicContact CG1-CG 4.49Å; V359-L363 WeakPolarHBondContact O-CG 3.29Å; V359-L363 PolarHBondContact O-N 3.32Å; N360-L363 PolarHBondContact O-N 2.75Å; L363-S366 PolarHBondContact O-N 2.91Å; L363-S367 PolarHBondContact O-N 3.33Å; L363-L397 HydrophobicContact CB-CD2 4.4Å
364	F	73.8	Confident	80.7	Confident	62 Å²	62	20.1 Å²	20.1	27%	0.272	11%	0.106	S	C	.	.	H	α-helix	trans	-60.9	-48.5	179	-175.6	-103.8	0	0	0	112.1	V209 N360 G361 S362 S366 S367	V209-F364 HydrophobicContact CG1-CD2 4.1Å; V209-F364 HydrophobicContact CG1-CE2 3.53Å; V209-F364 HydrophobicContact CG1-CZ 4.49Å; N360-F364 PolarHBondContact O-N 3.42Å; G361-F364 PolarHBondContact O-N 3.35Å; S362-F364 PolarHBondContact O-N 3.32Å; F364-S366 VanDerWaalsContact C-N 3.34Å; F364-S366 PolarHBondContact O-N 3.44Å; F364-S367 PolarHBondContact O-N 3Å; F364-S367 PolarHBondContact O-OG 2.84Å
365	T	75.5	Confident	80.5	Confident	40 Å²	40	28.2 Å²	28.2	25%	0.245	14%	0.137	C	C	.	.	H	α-helix	trans	-70.6	-29.5	-179.5	52.6	0	0	0	0	113.1	R160 Y279 G361 S362 S367 R368	R160-T365 PolarHBondContact NH1-OG1 3.33Å; Y279-T365 HydrophobicContact CD1-CG2 4.35Å; Y279-T365 HydrophobicContact CE1-CG2 4.28Å; G361-T365 WeakPolarHBondContact O-CG2 3.2Å; G361-T365 PolarHBondContact O-N 3.21Å; G361-T365 PolarHBondContact O-OG1 3.26Å; S362-T365 PolarHBondContact O-N 3.16Å; S362-T365 PolarHBondContact O-OG1 2.87Å; T365-S367 VanDerWaalsContact C-N 3.33Å; T365-S367 PolarHBondContact O-N 3.1Å; T365-R368 PolarHBondContact O-N 3.44Å
366	S	80.3	Confident	80.4	Confident	1 Å²	1	32.4 Å²	32.4	1%	0.007	16%	0.156	C	C	.	.	H	α-helix	trans	-61.8	-41.4	175.8	-58.8	0	0	0	0	111.4	R160 Q164 S362 L363 F364 R368 L369 F370	R160-S366 WeakPolarHBondContact CD-OG 3.36Å; Q164-S366 PolarHBondContact NE2-OG 3.37Å; S362-S366 WeakPolarHBondContact O-CB 3.04Å; S362-S366 PolarHBondContact O-N 3.25Å; S362-S366 PolarHBondContact O-OG 2.83Å; L363-S366 PolarHBondContact O-N 2.91Å; F364-S366 VanDerWaalsContact C-N 3.34Å; F364-S366 PolarHBondContact O-N 3.44Å; S366-R368 VanDerWaalsContact C-N 3.32Å; S366-R368 PolarHBondContact O-N 3.25Å; S366-L369 WeakPolarHBondContact O-CB 3.31Å; S366-L369 PolarHBondContact O-N 3.02Å; S366-L369 VanDerWaalsContact O-N 3.1Å; S366-F370 WeakPolarHBondContact O-CD2 3.34Å; S366-F370 PolarHBondContact O-N 3.38Å
367	S	77	Confident	80.3	Confident	10 Å²	10	32.9 Å²	32.9	7%	0.07	17%	0.172	C	C	.	.	H	α-helix	trans	-56.7	-42.9	-179.5	71.5	0	0	0	0	112.9	L363 F364 T365 L369 F370 F371	L363-S367 PolarHBondContact O-N 3.33Å; F364-S367 PolarHBondContact O-N 3Å; F364-S367 PolarHBondContact O-OG 2.84Å; T365-S367 VanDerWaalsContact C-N 3.33Å; T365-S367 PolarHBondContact O-N 3.1Å; S367-L369 PolarHBondContact O-N 3.42Å; S367-F370 WeakPolarHBondContact O-CB 3.45Å; S367-F370 PolarHBondContact O-N 2.89Å; S367-F370 VanDerWaalsContact O-N 3.09Å; S367-F371 WeakPolarHBondContact O-CD2 3.18Å; S367-F371 PolarHBondContact O-N 3.23Å
368	R	73.6	Confident	80.5	Confident	107 Å²	107	33.2 Å²	33.2	40%	0.404	17%	0.171	S	C	.	.	H	α-helix	trans	-57.7	-36	177.8	-66.8	-175.4	178.2	-161	-4.5	112.8	E286 T365 S366 F371 V372	E286-R368 IonicContact OE1-NH1 3.37Å; T365-R368 PolarHBondContact O-N 3.44Å; S366-R368 VanDerWaalsContact C-N 3.32Å; S366-R368 PolarHBondContact O-N 3.25Å; R368-F371 WeakPolarHBondContact O-CB 3.44Å; R368-F371 PolarHBondContact O-N 3.21Å; R368-V372 WeakPolarHBondContact O-CG2 3.49Å; R368-V372 PolarHBondContact O-N 3.03Å
369	L	79.4	Confident	80.7	Confident	11 Å²	11	32.5 Å²	32.5	6%	0.058	17%	0.165	C	C	.	.	H	α-helix	trans	-67.9	-37	178.6	-176	72.5	0	0	0	112.1	L152 E155 L156 S366 S367 F371 V372 G373	L152-L369 HydrophobicContact CD1-CD1 3.78Å; L152-L369 HydrophobicContact CD1-CD2 3.87Å; L152-L369 HydrophobicContact CD1-CG 3.57Å; E155-L369 HydrophobicContact CB-CD2 3.98Å; E155-L369 HydrophobicContact CG-CD2 3.24Å; L156-L369 HydrophobicContact CD2-CD2 3.91Å; S366-L369 WeakPolarHBondContact O-CB 3.31Å; S366-L369 PolarHBondContact O-N 3.02Å; S366-L369 VanDerWaalsContact O-N 3.1Å; S367-L369 PolarHBondContact O-N 3.42Å; L369-F371 VanDerWaalsContact C-N 3.33Å; L369-V372 PolarHBondContact O-N 3Å; L369-G373 PolarHBondContact O-N 3.09Å
370	F	83.1	Confident	80.7	Confident	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-63.7	-40	175	-69.3	-88.1	0	0	0	111.8	L156 S366 S367 G373 S374 L379 L383 F399 T400	L156-F370 HydrophobicContact CD1-CD1 4.23Å; L156-F370 HydrophobicContact CD1-CE1 3.81Å; L156-F370 HydrophobicContact CD1-CZ 4.38Å; L156-F370 HydrophobicContact CD2-CD1 4.12Å; L156-F370 HydrophobicContact CD2-CD2 4.25Å; L156-F370 HydrophobicContact CD2-CE1 3.51Å; L156-F370 HydrophobicContact CD2-CE2 3.63Å; L156-F370 HydrophobicContact CD2-CG 4.46Å; L156-F370 HydrophobicContact CD2-CZ 3.23Å; L156-F370 HydrophobicContact CG-CE1 4.24Å; L156-F370 HydrophobicContact CG-CZ 4.32Å; S366-F370 WeakPolarHBondContact O-CD2 3.34Å; S366-F370 PolarHBondContact O-N 3.38Å; S367-F370 WeakPolarHBondContact O-CB 3.45Å; S367-F370 PolarHBondContact O-N 2.89Å; S367-F370 VanDerWaalsContact O-N 3.09Å; F370-G373 PolarHBondContact O-N 2.72Å; F370-S374 WeakPolarHBondContact O-CB 3.27Å; F370-S374 PolarHBondContact O-N 3.24Å; F370-S374 PolarHBondContact O-OG 3.14Å; F370-L379 HydrophobicContact CD1-CD1 3.97Å; F370-L383 HydrophobicContact CB-CB 4.45Å; F370-L383 HydrophobicContact CD1-CB 4Å; F370-L383 HydrophobicContact CD1-CD1 3.95Å; F370-L383 HydrophobicContact CD1-CG 4.4Å; F370-L383 HydrophobicContact CE1-CD1 4.19Å; F370-F399 AromaticContact CE1-CD1 3.54Å; F370-F399 HydrophobicContact CE1-CD1 3.54Å; F370-F399 AromaticContact CE1-CE1 3.91Å; F370-F399 HydrophobicContact CE1-CE1 3.91Å; F370-F399 HydrophobicContact CE1-CG 4.36Å; F370-F399 AromaticContact CZ-CD1 3.55Å; F370-F399 HydrophobicContact CZ-CD1 3.55Å; F370-F399 HydrophobicContact CZ-CE1 4.04Å; F370-T400 HydrophobicContact CE2-CG2 3.31Å; F370-T400 HydrophobicContact CZ-CG2 3.51Å
371	F	75.3	Confident	80.7	Confident	41 Å²	41	39.5 Å²	39.5	18%	0.18	21%	0.212	C	C	.	.	H	α-helix	trans	-59.8	-47.8	175.1	-74.5	-75.9	0	0	0	112.4	S367 R368 L369 S374 R375 S384 I386 P393	S367-F371 WeakPolarHBondContact O-CD2 3.18Å; S367-F371 PolarHBondContact O-N 3.23Å; R368-F371 WeakPolarHBondContact O-CB 3.44Å; R368-F371 PolarHBondContact O-N 3.21Å; L369-F371 VanDerWaalsContact C-N 3.33Å; F371-S374 PolarHBondContact O-N 3.48Å; F371-S374 PolarHBondContact O-OG 3.22Å; F371-S374 VanDerWaalsContact O-OG 3.11Å; F371-R375 WeakPolarHBondContact O-CB 3.35Å; F371-R375 PolarHBondContact O-N 2.92Å; F371-S384 WeakPolarHBondContact CE1-O 3.45Å; F371-I386 HydrophobicContact CE1-CD1 3.81Å; F371-I386 HydrophobicContact CE1-CG1 3.78Å; F371-I386 HydrophobicContact CZ-CD1 3.84Å; F371-I386 HydrophobicContact CZ-CG1 3.71Å; F371-P393 HydrophobicContact CE2-CB 3.63Å; F371-P393 HydrophobicContact CE2-CG 4.13Å; F371-P393 HydrophobicContact CZ-CB 3.63Å; F371-P393 HydrophobicContact CZ-CG 4.47Å
372	V	76.8	Confident	81.2	Confident	17 Å²	17	40.1 Å²	40.1	10%	0.103	21%	0.212	C	C	.	.	H	α-helix	trans	-65.7	-42.4	178.8	177.4	0	0	0	0	110.6	Y136 R368 L369 S374 R375 E376	Y136-V372 HydrophobicContact CD1-CG1 3.82Å; Y136-V372 HydrophobicContact CE1-CG1 3.8Å; R368-V372 WeakPolarHBondContact O-CG2 3.49Å; R368-V372 PolarHBondContact O-N 3.03Å; L369-V372 PolarHBondContact O-N 3Å; V372-S374 PolarHBondContact O-N 3.37Å; V372-R375 PolarHBondContact O-N 3.33Å; V372-E376 WeakPolarHBondContact O-CG 3.37Å; V372-E376 PolarHBondContact O-N 2.94Å
373	G	83.4	Confident	81.4	Confident	0 Å²	0	40.6 Å²	40.6	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-64.6	-36	179.1	0	0	0	0	0	114.2	L369 F370 H378 L379	L369-G373 PolarHBondContact O-N 3.09Å; F370-G373 PolarHBondContact O-N 2.72Å; G373-H378 WeakPolarHBondContact O-CB 3.46Å; G373-H378 PolarHBondContact O-N 3.47Å; G373-L379 PolarHBondContact O-N 2.97Å; G373-L379 VanDerWaalsContact O-N 3.1Å
374	S	84.1	Confident	81.5	Confident	18 Å²	18	41.4 Å²	41.4	13%	0.126	22%	0.219	C	C	.	.	H	α-helix	trans	-76.7	-36.4	177.1	74.9	0	0	0	0	112.4	F370 F371 V372 E376 G377 S384	F370-S374 WeakPolarHBondContact O-CB 3.27Å; F370-S374 PolarHBondContact O-N 3.24Å; F370-S374 PolarHBondContact O-OG 3.14Å; F371-S374 PolarHBondContact O-N 3.48Å; F371-S374 PolarHBondContact O-OG 3.22Å; F371-S374 VanDerWaalsContact O-OG 3.11Å; V372-S374 PolarHBondContact O-N 3.37Å; S374-E376 VanDerWaalsContact C-N 3.26Å; S374-E376 PolarHBondContact O-N 3.08Å; S374-G377 WeakPolarHBondContact O-CA 3.36Å; S374-G377 PolarHBondContact O-N 3.42Å; S374-S384 WeakPolarHBondContact CB-OG 3.49Å; S374-S384 WeakPolarHBondContact OG-CB 3.48Å; S374-S384 PolarHBondContact OG-OG 3.38Å
375	R	80.9	Confident	82.2	Confident	174 Å²	174	38.7 Å²	38.7	66%	0.657	21%	0.207	S	C	*	.	H	α-helix	trans	-60.6	-37.5	177.5	-171.4	178	70.3	-175.9	0.7	111.7	F371 V372 G377	F371-R375 WeakPolarHBondContact O-CB 3.35Å; F371-R375 PolarHBondContact O-N 2.92Å; V372-R375 PolarHBondContact O-N 3.33Å; R375-G377 PolarHBondContact O-N 2.88Å
376	E	83.7	Confident	82.7	Confident	87 Å²	87	38.7 Å²	38.7	41%	0.407	21%	0.205	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.4	3.4	174.1	-62.6	-62.6	152.4	0	0	113.4	Y136 L140 V372 S374 H378	Y136-E376 HydrophobicContact CE1-CG 4.01Å; Y136-E376 VanDerWaalsContact OH-CB 3.28Å; Y136-E376 WeakPolarHBondContact OH-CB 3.28Å; Y136-E376 WeakPolarHBondContact OH-CG 3.27Å; L140-E376 HydrophobicContact CD2-CG 4.25Å; V372-E376 WeakPolarHBondContact O-CG 3.37Å; V372-E376 PolarHBondContact O-N 2.94Å; S374-E376 VanDerWaalsContact C-N 3.26Å; S374-E376 PolarHBondContact O-N 3.08Å; E376-H378 PolarHBondContact O-N 3.48Å
377	G	83.6	Confident	83	Confident	48 Å²	48	39.6 Å²	39.6	50%	0.495	21%	0.209	S	C	.	.	T	Hydrogen-bonded Turn	trans	72.5	10.6	178.8	0	0	0	0	0	114.9	S374 R375	S374-G377 WeakPolarHBondContact O-CA 3.36Å; S374-G377 PolarHBondContact O-N 3.42Å; R375-G377 PolarHBondContact O-N 2.88Å
378	H	86.1	Confident	83.3	Confident	14 Å²	14	41.8 Å²	41.8	7%	0.065	22%	0.223	C	C	.	.	S	Bend	trans	-84.1	-27.3	179.8	-74.7	174.6	0	0	0	112.9	Y136 S145 F149 L152 G373 E376	Y136-H378 AromaticContact CE2-ND1 3.74Å; Y136-H378 AromaticContact CZ-ND1 3.67Å; Y136-H378 PolarHBondContact OH-CE1 3.39Å; Y136-H378 VanDerWaalsContact OH-CE1 3.25Å; Y136-H378 PolarHBondContact OH-ND1 3.26Å; S145-H378 PolarHBondContact OG-CE1 3.27Å; S145-H378 PolarHBondContact OG-NE2 2.84Å; F149-H378 HydrophobicContact CD2-CB 3.96Å; F149-H378 WeakPolarHBondContact CE2-O 3.49Å; L152-H378 HydrophobicContact CD2-CB 4.17Å; G373-H378 WeakPolarHBondContact O-CB 3.46Å; G373-H378 PolarHBondContact O-N 3.47Å; E376-H378 PolarHBondContact O-N 3.48Å
379	L	86.9	Confident	83.8	Confident	19 Å²	19	41.6 Å²	41.6	10%	0.099	23%	0.234	C	C	.	.	S	Bend	trans	-113.7	153.2	175.8	-65.8	173.9	0	0	0	111.8	L152 L156 F370 G373 S381 L383	L152-L379 HydrophobicContact CD2-CD1 3.86Å; L152-L379 HydrophobicContact CD2-CD2 4.22Å; L152-L379 HydrophobicContact CD2-CG 3.77Å; L152-L379 HydrophobicContact CG-CD1 4.42Å; L156-L379 HydrophobicContact CD1-CD1 3.88Å; L156-L379 HydrophobicContact CD1-CD2 3.84Å; L156-L379 HydrophobicContact CD1-CG 4.49Å; F370-L379 HydrophobicContact CD1-CD1 3.97Å; G373-L379 PolarHBondContact O-N 2.97Å; G373-L379 VanDerWaalsContact O-N 3.1Å; L379-S381 PolarHBondContact O-N 3.21Å; L379-L383 HydrophobicContact CB-CD1 4.5Å
380	P	86.2	Confident	83.9	Confident	82 Å²	82	44 Å²	44	53%	0.532	25%	0.246	S	C	.	.			trans	-55.3	137.5	170.7	-23.7	33.5	0	0	0	111.7	L382 L383	P380-L382 PolarHBondContact O-N 3.4Å; P380-L383 PolarHBondContact O-N 3.41Å
381	S	84.8	Confident	83.8	Confident	72 Å²	72	50.1 Å²	50.1	50%	0.503	28%	0.279	S	S	.	.	G	3₁₀ helix	trans	-58.7	-23.8	-178.9	55.5	0	0	0	0	113.8	L379 L383 S384 M385	L379-S381 PolarHBondContact O-N 3.21Å; S381-L383 PolarHBondContact O-N 3.16Å; S381-S384 PolarHBondContact O-N 3.16Å; S381-S384 PolarHBondContact O-OG 3.25Å; S381-M385 WeakPolarHBondContact O-CG 3.44Å
382	L	86.6	Confident	84.2	Confident	27 Å²	27	48.1 Å²	48.1	14%	0.141	27%	0.27	C	S	.	.	G	3₁₀ helix	trans	-55.5	-38.1	174.8	-177.5	65.1	0	0	0	112.6	P380 S384 M385 P395 T513 C516 Q517 V522	P380-L382 PolarHBondContact O-N 3.4Å; L382-S384 PolarHBondContact O-N 3.16Å; L382-M385 HydrophobicContact CD1-SD 3.83Å; L382-M385 PolarHBondContact O-N 3.4Å; L382-P395 HydrophobicContact CD1-CG 4.49Å; L382-P395 HydrophobicContact CG-CB 4.35Å; L382-P395 WeakPolarHBondContact O-CB 3.26Å; L382-P395 WeakPolarHBondContact O-CG 3.28Å; L382-T513 HydrophobicContact CB-CG2 4.3Å; L382-T513 HydrophobicContact CD1-CG2 4.4Å; L382-C516 HydrophobicContact CD1-CB 3.66Å; L382-C516 HydrophobicContact CD2-CB 3.57Å; L382-C516 HydrophobicContact CG-CB 4.27Å; L382-Q517 HydrophobicContact CD1-CG 4.47Å; L382-V522 HydrophobicContact CD1-CG2 4.36Å
383	L	86.1	Confident	84.6	Confident	23 Å²	23	48 Å²	48	12%	0.12	27%	0.269	C	S	.	.	G	3₁₀ helix	trans	-72.9	-10.7	-174.8	-66.5	175.6	0	0	0	113.5	F370 L379 P380 S381 S396 F399	F370-L383 HydrophobicContact CB-CB 4.45Å; F370-L383 HydrophobicContact CD1-CB 4Å; F370-L383 HydrophobicContact CD1-CD1 3.95Å; F370-L383 HydrophobicContact CD1-CG 4.4Å; F370-L383 HydrophobicContact CE1-CD1 4.19Å; L379-L383 HydrophobicContact CB-CD1 4.5Å; P380-L383 PolarHBondContact O-N 3.41Å; S381-L383 PolarHBondContact O-N 3.16Å; L383-S396 WeakPolarHBondContact O-CB 3.19Å; L383-F399 HydrophobicContact CD2-CB 4.07Å; L383-F399 HydrophobicContact CD2-CG 4.31Å
384	S	84.8	Confident	84.8	Confident	16 Å²	16	49.2 Å²	49.2	11%	0.112	28%	0.276	C	S	.	.	G	3₁₀ helix	trans	-110.9	14.7	174.2	57.8	0	0	0	0	113.7	F371 S374 S381 L382	F371-S384 WeakPolarHBondContact CE1-O 3.45Å; S374-S384 WeakPolarHBondContact CB-OG 3.49Å; S374-S384 WeakPolarHBondContact OG-CB 3.48Å; S374-S384 PolarHBondContact OG-OG 3.38Å; S381-S384 PolarHBondContact O-N 3.16Å; S381-S384 PolarHBondContact O-OG 3.25Å; L382-S384 PolarHBondContact O-N 3.16Å
385	M	87.9	Confident	85.1	Confident	5 Å²	5	48.7 Å²	48.7	3%	0.025	27%	0.272	C	S	.	.			trans	-80.9	151.5	175.5	-62.6	-177.4	-176.5	0	0	111	S381 L382 T513 Q517 V522 V523 P524	S381-M385 WeakPolarHBondContact O-CG 3.44Å; L382-M385 HydrophobicContact CD1-SD 3.83Å; L382-M385 PolarHBondContact O-N 3.4Å; M385-T513 HydrophobicContact CE-CG2 3.76Å; M385-Q517 HydrophobicContact CE-CG 4.16Å; M385-Q517 HydrophobicContact SD-CG 3.42Å; M385-Q517 WeakPolarHBondContact SD-CG 3.42Å; M385-Q517 PolarHBondContact SD-NE2 3.18Å; M385-V522 HydrophobicContact CB-CB 3.8Å; M385-V522 HydrophobicContact CB-CG2 3.78Å; M385-V522 HydrophobicContact SD-CG2 4.08Å; M385-V523 CarbonylContact C-O 3.45Å; M385-V523 VanDerWaalsContact CA-O 3.3Å; M385-V523 WeakPolarHBondContact CA-O 3.28Å; M385-V523 WeakPolarHBondContact CB-O 3.34Å; M385-P524 HydrophobicContact CE-CG 4.3Å
386	I	86.6	Confident	85.5	Confident	40 Å²	40	40.4 Å²	40.4	21%	0.205	24%	0.241	C	C	.	.	B	Isolated β-bridge	trans	-121.7	143.1	-174.1	-54.9	178.5	0	0	0	108.9	F371 L391 V522 V523	F371-I386 HydrophobicContact CE1-CD1 3.81Å; F371-I386 HydrophobicContact CE1-CG1 3.78Å; F371-I386 HydrophobicContact CZ-CD1 3.84Å; F371-I386 HydrophobicContact CZ-CG1 3.71Å; I386-L391 VanDerWaalsContact CG2-C 3.46Å; I386-V522 WeakPolarHBondContact O-CA 3.38Å; I386-V523 PolarHBondContact N-O 3.23Å; I386-V523 WeakPolarHBondContact O-CG2 3.5Å; I386-V523 PolarHBondContact O-N 3.39Å
387	H	86.4	Confident	85.8	Confident	21 Å²	21	36.5 Å²	36.5	10%	0.097	22%	0.223	C	C	.	.			trans	-71.9	130.8	172.3	-165.7	-69.6	0	0	0	110.8	T389 L390 L391 T392 M520 E521	H387-T389 PolarHBondContact CE1-OG1 3.22Å; H387-T389 PolarHBondContact ND1-N 3.18Å; H387-T389 PolarHBondContact ND1-OG1 2.48Å; H387-T389 VanDerWaalsContact ND1-OG1 3.08Å; H387-T389 PolarHBondContact O-N 3.07Å; H387-L390 HydrophobicContact CB-CB 4.34Å; H387-L391 VanDerWaalsContact O-CA 3.22Å; H387-L391 WeakPolarHBondContact O-CA 3.08Å; H387-L391 PolarHBondContact O-N 3.44Å; H387-T392 PolarHBondContact N-O 3.15Å; H387-M520 PolarHBondContact CD2-O 3.03Å; H387-E521 PolarHBondContact CD2-O 3.08Å
388	P	84.1	Confident	86.2	Confident	56 Å²	56	37.6 Å²	37.6	36%	0.364	22%	0.216	S	C	.	.	T	Hydrogen-bonded Turn	trans	-67.7	-39.5	-170.6	24.8	-32.6	0	0	0	113.6	E521 V523	P388-E521 WeakPolarHBondContact CD-O 3.4Å; P388-E521 HydrophobicContact CG-CG 4.32Å; P388-V523 HydrophobicContact CB-CG2 4.39Å
389	T	82.9	Confident	86.5	Confident	102 Å²	102	39.8 Å²	39.8	63%	0.626	23%	0.226	S	C	*	.	T	Hydrogen-bonded Turn	trans	-83.5	-42.7	-178.9	59	0	0	0	0	113.6	H387	H387-T389 PolarHBondContact CE1-OG1 3.22Å; H387-T389 PolarHBondContact ND1-N 3.18Å; H387-T389 PolarHBondContact ND1-OG1 2.48Å; H387-T389 VanDerWaalsContact ND1-OG1 3.08Å; H387-T389 PolarHBondContact O-N 3.07Å
390	L	80.7	Confident	86.7	Confident	61 Å²	61	39.1 Å²	39.1	32%	0.319	22%	0.222	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.4	-18.4	-175.7	-56.5	177.7	0	0	0	113.3	C206 H387 T392	C206-L390 WeakPolarHBondContact O-CD1 3.25Å; H387-L390 HydrophobicContact CB-CB 4.34Å; L390-T392 HydrophobicContact CB-CG2 4.27Å; L390-T392 PolarHBondContact O-N 2.94Å
391	L	83	Confident	87	Confident	129 Å²	129	35.6 Å²	35.6	68%	0.675	20%	0.2	S	C	*	.			trans	57.1	35	-176.9	-54.9	172.1	0	0	0	112.7	I386 H387	I386-L391 VanDerWaalsContact CG2-C 3.46Å; H387-L391 VanDerWaalsContact O-CA 3.22Å; H387-L391 WeakPolarHBondContact O-CA 3.08Å; H387-L391 PolarHBondContact O-N 3.44Å
392	T	82.7	Confident	87.5	Confident	0 Å²	0	36.7 Å²	36.7	0%	0	20%	0.199	C	C	.	.			trans	-112.1	143.6	-177	50.2	0	0	0	0	111.9	N205 C206 V209 H387 L390 L394	N205-T392 VanDerWaalsContact O-CG2 3.26Å; N205-T392 WeakPolarHBondContact O-CG2 3.47Å; C206-T392 WeakPolarHBondContact O-CB 3.48Å; C206-T392 WeakPolarHBondContact O-CG2 3.34Å; C206-T392 PolarHBondContact O-OG1 2.87Å; V209-T392 HydrophobicContact CG2-CG2 3.49Å; V209-T392 VanDerWaalsContact CG2-CG2 3.49Å; H387-T392 PolarHBondContact N-O 3.15Å; L390-T392 HydrophobicContact CB-CG2 4.27Å; L390-T392 PolarHBondContact O-N 2.94Å; T392-L394 VanDerWaalsContact C-N 3.27Å; T392-L394 PolarHBondContact O-N 3.32Å
393	P	85.9	Confident	87.9	Confident	13 Å²	13	37.1 Å²	37.1	8%	0.084	20%	0.201	C	C	.	.			trans	-83.3	66.8	-179.9	34.7	-36	0	0	0	111.9	F371 P395 S396 L397	F371-P393 HydrophobicContact CE2-CB 3.63Å; F371-P393 HydrophobicContact CE2-CG 4.13Å; F371-P393 HydrophobicContact CZ-CB 3.63Å; F371-P393 HydrophobicContact CZ-CG 4.47Å; P393-P395 VanDerWaalsContact C-CD 3.5Å; P393-S396 WeakPolarHBondContact CB-OG 3.49Å; P393-S396 PolarHBondContact O-N 2.96Å; P393-S396 PolarHBondContact O-OG 3.06Å; P393-L397 HydrophobicContact CG-CD1 4.4Å; P393-L397 HydrophobicContact CG-CG 4.42Å; P393-L397 PolarHBondContact O-N 3.29Å
394	L	87.6	Confident	88.3	Confident	27 Å²	27	36 Å²	36	14%	0.141	20%	0.195	C	C	.	.	H	α-helix	trans	-51.6	-48	-171.4	-161.1	104.3	0	0	0	114.4	C206 T392 S396 L397 I398 M520 V522	C206-L394 HydrophobicContact CB-CD1 3.67Å; T392-L394 VanDerWaalsContact C-N 3.27Å; T392-L394 PolarHBondContact O-N 3.32Å; L394-S396 VanDerWaalsContact C-N 3.33Å; L394-S396 PolarHBondContact O-N 3.17Å; L394-L397 PolarHBondContact O-N 2.81Å; L394-I398 HydrophobicContact CD2-CD1 3.65Å; L394-I398 HydrophobicContact CG-CD1 3.87Å; L394-I398 WeakPolarHBondContact O-CG1 3.2Å; L394-I398 PolarHBondContact O-N 3.37Å; L394-M520 HydrophobicContact CD2-CB 3.59Å; L394-M520 HydrophobicContact CD2-CG 3.74Å; L394-M520 HydrophobicContact CD2-SD 4.04Å; L394-V522 HydrophobicContact CB-CG1 4.14Å
395	P	90.5	Very high	88.7	Confident	6 Å²	6	37.5 Å²	37.5	4%	0.039	20%	0.202	C	C	.	.	H	α-helix	trans	-66.3	-36.4	-175.1	-20.5	35.3	0	0	0	112.2	L382 P393 F399 M520 V522	L382-P395 HydrophobicContact CD1-CG 4.49Å; L382-P395 HydrophobicContact CG-CB 4.35Å; L382-P395 WeakPolarHBondContact O-CB 3.26Å; L382-P395 WeakPolarHBondContact O-CG 3.28Å; P393-P395 VanDerWaalsContact C-CD 3.5Å; P395-F399 WeakPolarHBondContact O-CB 3.32Å; P395-F399 PolarHBondContact O-N 3.21Å; P395-M520 HydrophobicContact CB-SD 4.14Å; P395-M520 HydrophobicContact CG-SD 3.97Å; P395-V522 HydrophobicContact CG-CB 4.41Å; P395-V522 HydrophobicContact CG-CG1 4.04Å; P395-V522 HydrophobicContact CG-CG2 3.98Å
396	S	88.8	Confident	89	Confident	1 Å²	1	41.8 Å²	41.8	1%	0.007	22%	0.224	C	C	.	.	H	α-helix	trans	-64.9	-42	177.1	76	0	0	0	0	111.9	L383 P393 L394 F399 T400	L383-S396 WeakPolarHBondContact O-CB 3.19Å; P393-S396 WeakPolarHBondContact CB-OG 3.49Å; P393-S396 PolarHBondContact O-N 2.96Å; P393-S396 PolarHBondContact O-OG 3.06Å; L394-S396 VanDerWaalsContact C-N 3.33Å; L394-S396 PolarHBondContact O-N 3.17Å; S396-F399 PolarHBondContact O-N 3.43Å; S396-T400 WeakPolarHBondContact O-CG2 3.11Å; S396-T400 PolarHBondContact O-N 3.42Å; S396-T400 PolarHBondContact O-OG1 2.96Å
397	L	89.4	Confident	89.3	Confident	4 Å²	4	41.5 Å²	41.5	2%	0.021	22%	0.221	C	C	.	.	H	α-helix	trans	-69.4	-38	-179.5	-69.6	173.5	0	0	0	111.9	T202 N205 L363 P393 L394 T400 C401	T202-L397 HydrophobicContact CG2-CB 4.28Å; N205-L397 HydrophobicContact CB-CD1 3.96Å; N205-L397 HydrophobicContact CB-CD2 4.4Å; L363-L397 HydrophobicContact CB-CD2 4.4Å; P393-L397 HydrophobicContact CG-CD1 4.4Å; P393-L397 HydrophobicContact CG-CG 4.42Å; P393-L397 PolarHBondContact O-N 3.29Å; L394-L397 PolarHBondContact O-N 2.81Å; L397-T400 WeakPolarHBondContact CA-OG1 3.37Å; L397-T400 PolarHBondContact O-OG1 3.22Å; L397-C401 WeakPolarHBondContact O-CB 3.45Å; L397-C401 PolarHBondContact O-N 3.46Å
398	I	91.8	Very high	89.5	Confident	71 Å²	71	41.2 Å²	41.2	36%	0.364	22%	0.222	S	C	.	.	H	α-helix	trans	-66.4	-43.5	174.9	-67.5	169.2	0	0	0	110.2	L394 C401 L402 M520	L394-I398 HydrophobicContact CD2-CD1 3.65Å; L394-I398 HydrophobicContact CG-CD1 3.87Å; L394-I398 WeakPolarHBondContact O-CG1 3.2Å; L394-I398 PolarHBondContact O-N 3.37Å; I398-C401 PolarHBondContact O-N 2.93Å; I398-L402 WeakPolarHBondContact O-CB 3.43Å; I398-L402 PolarHBondContact O-N 3.47Å; I398-M520 HydrophobicContact CD1-CE 4.01Å; I398-M520 HydrophobicContact CD1-SD 4.13Å
399	F	92.4	Very high	89.7	Confident	60 Å²	60	46.4 Å²	46.4	26%	0.263	24%	0.239	S	C	.	.	H	α-helix	trans	-62	-47	178.3	179.6	-89.6	0	0	0	111.9	L157 F370 L383 P395 S396 L402 M403	L157-F399 HydrophobicContact CD2-CZ 4.22Å; F370-F399 AromaticContact CE1-CD1 3.54Å; F370-F399 HydrophobicContact CE1-CD1 3.54Å; F370-F399 AromaticContact CE1-CE1 3.91Å; F370-F399 HydrophobicContact CE1-CE1 3.91Å; F370-F399 HydrophobicContact CE1-CG 4.36Å; F370-F399 AromaticContact CZ-CD1 3.55Å; F370-F399 HydrophobicContact CZ-CD1 3.55Å; F370-F399 HydrophobicContact CZ-CE1 4.04Å; L383-F399 HydrophobicContact CD2-CB 4.07Å; L383-F399 HydrophobicContact CD2-CG 4.31Å; P395-F399 WeakPolarHBondContact O-CB 3.32Å; P395-F399 PolarHBondContact O-N 3.21Å; S396-F399 PolarHBondContact O-N 3.43Å; F399-L402 PolarHBondContact O-N 3.2Å; F399-M403 HydrophobicContact CD1-CG 4.24Å; F399-M403 HydrophobicContact CD2-CE 4.33Å; F399-M403 HydrophobicContact CE1-CE 4.48Å; F399-M403 HydrophobicContact CE1-CG 3.84Å; F399-M403 HydrophobicContact CE2-CE 3.59Å; F399-M403 HydrophobicContact CE2-CG 4.48Å; F399-M403 HydrophobicContact CZ-CE 3.69Å; F399-M403 HydrophobicContact CZ-CG 3.97Å; F399-M403 HydrophobicContact CZ-SD 4.46Å; F399-M403 WeakPolarHBondContact O-CG 3.31Å; F399-M403 PolarHBondContact O-N 2.77Å
400	T	91.2	Very high	89.9	Confident	5 Å²	5	42.8 Å²	42.8	3%	0.031	22%	0.218	C	C	.	.	H	α-helix	trans	-63.6	-43.6	176.8	50.7	0	0	0	0	111.7	F370 S396 L397 L402 M403 T404	F370-T400 HydrophobicContact CE2-CG2 3.31Å; F370-T400 HydrophobicContact CZ-CG2 3.51Å; S396-T400 WeakPolarHBondContact O-CG2 3.11Å; S396-T400 PolarHBondContact O-N 3.42Å; S396-T400 PolarHBondContact O-OG1 2.96Å; L397-T400 WeakPolarHBondContact CA-OG1 3.37Å; L397-T400 PolarHBondContact O-OG1 3.22Å; T400-L402 VanDerWaalsContact C-N 3.34Å; T400-L402 PolarHBondContact O-N 3.17Å; T400-M403 PolarHBondContact O-N 2.7Å; T400-T404 WeakPolarHBondContact O-CB 3Å; T400-T404 PolarHBondContact O-N 3.24Å; T400-T404 PolarHBondContact O-OG1 3.34Å
401	C	93.8	Very high	89.8	Confident	8 Å²	8	46.6 Å²	46.6	5%	0.054	24%	0.239	C	C	.	.	H	α-helix	trans	-55.4	-49.9	175.9	-173.6	0	0	0	0	111.3	T202 L397 I398 M403 T404 L405	T202-C401 HydrophobicContact CG2-CB 3.75Å; T202-C401 WeakPolarHBondContact OG1-CB 3.38Å; T202-C401 PolarHBondContact OG1-SG 3Å; T202-C401 VanDerWaalsContact OG1-SG 3.41Å; L397-C401 WeakPolarHBondContact O-CB 3.45Å; L397-C401 PolarHBondContact O-N 3.46Å; I398-C401 PolarHBondContact O-N 2.93Å; C401-M403 PolarHBondContact O-N 2.58Å; C401-T404 PolarHBondContact O-N 3.04Å; C401-L405 VanDerWaalsContact O-CG 3.31Å; C401-L405 WeakPolarHBondContact O-CG 3.3Å; C401-L405 PolarHBondContact O-N 2.85Å
402	L	94.6	Very high	89.7	Confident	95 Å²	95	44 Å²	44	50%	0.497	23%	0.226	S	C	.	.	H	α-helix	trans	-59.7	-45.3	178.9	-174	145.6	0	0	0	111.7	I398 F399 T400 T404 L405 L406	I398-L402 WeakPolarHBondContact O-CB 3.43Å; I398-L402 PolarHBondContact O-N 3.47Å; F399-L402 PolarHBondContact O-N 3.2Å; T400-L402 VanDerWaalsContact C-N 3.34Å; T400-L402 PolarHBondContact O-N 3.17Å; L402-T404 VanDerWaalsContact C-N 3.35Å; L402-T404 PolarHBondContact O-N 2.95Å; L402-L405 PolarHBondContact O-N 2.98Å; L402-L406 HydrophobicContact CD2-CD1 4.4Å; L402-L406 PolarHBondContact O-N 3.06Å
403	M	93.9	Very high	89.7	Confident	36 Å²	36	45.1 Å²	45.1	18%	0.177	23%	0.231	C	C	.	.	H	α-helix	trans	-63.8	-39.9	177.3	-68.2	-61	154	0	0	112	L157 P161 F399 T400 C401 L405 L406 Y407	L157-M403 HydrophobicContact CD2-CE 4.26Å; L157-M403 HydrophobicContact CD2-CG 4.36Å; L157-M403 HydrophobicContact CD2-SD 3.79Å; P161-M403 HydrophobicContact CB-CB 3.97Å; P161-M403 HydrophobicContact CG-CB 3.65Å; F399-M403 HydrophobicContact CD1-CG 4.24Å; F399-M403 HydrophobicContact CD2-CE 4.33Å; F399-M403 HydrophobicContact CE1-CE 4.48Å; F399-M403 HydrophobicContact CE1-CG 3.84Å; F399-M403 HydrophobicContact CE2-CE 3.59Å; F399-M403 HydrophobicContact CE2-CG 4.48Å; F399-M403 HydrophobicContact CZ-CE 3.69Å; F399-M403 HydrophobicContact CZ-CG 3.97Å; F399-M403 HydrophobicContact CZ-SD 4.46Å; F399-M403 WeakPolarHBondContact O-CG 3.31Å; F399-M403 PolarHBondContact O-N 2.77Å; T400-M403 PolarHBondContact O-N 2.7Å; C401-M403 PolarHBondContact O-N 2.58Å; M403-L405 VanDerWaalsContact C-N 3.34Å; M403-L405 PolarHBondContact O-N 2.88Å; M403-L406 WeakPolarHBondContact O-CB 3.44Å; M403-L406 PolarHBondContact O-N 2.82Å; M403-L406 HydrophobicContact SD-CD1 3.98Å; M403-Y407 WeakPolarHBondContact O-CD2 3.39Å
404	T	94.7	Very high	89.5	Confident	0 Å²	0	46.5 Å²	46.5	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-66.2	-37.6	178.1	-58.1	0	0	0	0	111.3	P161 Q164 I198 T400 C401 L402 L406 Y407	P161-T404 WeakPolarHBondContact CA-OG1 3.38Å; Q164-T404 HydrophobicContact CB-CG2 3.66Å; Q164-T404 PolarHBondContact OE1-OG1 3.24Å; I198-T404 HydrophobicContact CD1-CG2 3.47Å; I198-T404 VanDerWaalsContact CD1-CG2 3.47Å; I198-T404 HydrophobicContact CG1-CG2 4.11Å; I198-T404 HydrophobicContact CG2-CG2 4.25Å; T400-T404 WeakPolarHBondContact O-CB 3Å; T400-T404 PolarHBondContact O-N 3.24Å; T400-T404 PolarHBondContact O-OG1 3.34Å; C401-T404 PolarHBondContact O-N 3.04Å; L402-T404 VanDerWaalsContact C-N 3.35Å; L402-T404 PolarHBondContact O-N 2.95Å; T404-L406 VanDerWaalsContact C-N 3.3Å; T404-L406 PolarHBondContact O-N 3.35Å; T404-Y407 WeakPolarHBondContact O-CB 3.22Å; T404-Y407 PolarHBondContact O-N 2.8Å
405	L	94.9	Very high	89.3	Confident	48 Å²	48	46.9 Å²	46.9	25%	0.251	24%	0.241	S	C	.	.	H	α-helix	trans	-65.4	-30.2	175.9	-68.6	176.4	0	0	0	112.9	C195 L199 C401 L402 M403 Y407 A408	C195-L405 HydrophobicContact CB-CD2 3.75Å; L199-L405 HydrophobicContact CD2-CD1 4.12Å; L199-L405 HydrophobicContact CG-CD1 4.44Å; C401-L405 VanDerWaalsContact O-CG 3.31Å; C401-L405 WeakPolarHBondContact O-CG 3.3Å; C401-L405 PolarHBondContact O-N 2.85Å; L402-L405 PolarHBondContact O-N 2.98Å; M403-L405 VanDerWaalsContact C-N 3.34Å; M403-L405 PolarHBondContact O-N 2.88Å; L405-Y407 PolarHBondContact O-N 3.43Å; L405-A408 WeakPolarHBondContact O-CB 3.46Å; L405-A408 PolarHBondContact O-N 2.9Å
406	L	93.8	Very high	89.1	Confident	94 Å²	94	47 Å²	47	49%	0.492	24%	0.241	S	C	.	.	H	α-helix	trans	-62.8	-29.6	174.8	-66.5	176.9	0	0	0	112.3	L402 M403 T404 A408 F409	L402-L406 HydrophobicContact CD2-CD1 4.4Å; L402-L406 PolarHBondContact O-N 3.06Å; M403-L406 WeakPolarHBondContact O-CB 3.44Å; M403-L406 PolarHBondContact O-N 2.82Å; M403-L406 HydrophobicContact SD-CD1 3.98Å; T404-L406 VanDerWaalsContact C-N 3.3Å; T404-L406 PolarHBondContact O-N 3.35Å; L406-A408 PolarHBondContact O-N 3.26Å; L406-F409 HydrophobicContact CD2-CD2 4.49Å; L406-F409 HydrophobicContact CD2-CE2 4.19Å; L406-F409 WeakPolarHBondContact O-CD2 3.47Å; L406-F409 PolarHBondContact O-N 2.82Å
407	Y	92.2	Very high	88.9	Confident	35 Å²	35	47 Å²	47	14%	0.137	24%	0.241	C	C	.	.	G	3₁₀ helix	trans	-69.9	-14.5	175	-81.2	-90.9	0	0	0	113.3	L157 P161 Y165 M403 T404 L405 F409 S410 V416 F419	L157-Y407 WeakPolarHBondContact O-CE2 3.32Å; L157-Y407 PolarHBondContact O-OH 2.8Å; P161-Y407 HydrophobicContact CB-CD2 3.78Å; P161-Y407 HydrophobicContact CB-CE2 3.72Å; Y165-Y407 WeakPolarHBondContact CE1-O 3.16Å; M403-Y407 WeakPolarHBondContact O-CD2 3.39Å; T404-Y407 WeakPolarHBondContact O-CB 3.22Å; T404-Y407 PolarHBondContact O-N 2.8Å; L405-Y407 PolarHBondContact O-N 3.43Å; Y407-F409 PolarHBondContact O-N 3.39Å; Y407-S410 VanDerWaalsContact O-CB 3.24Å; Y407-S410 WeakPolarHBondContact O-CB 3.42Å; Y407-S410 PolarHBondContact O-N 3.42Å; Y407-S410 PolarHBondContact O-OG 2.93Å; Y407-V416 HydrophobicContact CD1-CG1 3.88Å; Y407-V416 HydrophobicContact CD1-CG2 4.42Å; Y407-V416 HydrophobicContact CE1-CG1 4.25Å; Y407-F419 HydrophobicContact CE1-CD1 4.24Å; Y407-F419 HydrophobicContact CE1-CE1 4.35Å; Y407-F419 VanDerWaalsContact OH-CE1 3.3Å; Y407-F419 WeakPolarHBondContact OH-CE1 3.43Å
408	A	91	Very high	88.6	Confident	14 Å²	14	47.9 Å²	47.9	12%	0.116	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-64.7	-19.4	172.9	0	0	0	0	0	113.6	Y165 K191 C195 L405 L406 S410	Y165-A408 HydrophobicContact CD2-CB 4.46Å; Y165-A408 HydrophobicContact CE2-CB 3.79Å; K191-A408 WeakPolarHBondContact CD-O 3.36Å; K191-A408 WeakPolarHBondContact CE-O 3.42Å; C195-A408 VanDerWaalsContact SG-CB 3.59Å; L405-A408 WeakPolarHBondContact O-CB 3.46Å; L405-A408 PolarHBondContact O-N 2.9Å; L406-A408 PolarHBondContact O-N 3.26Å; A408-S410 PolarHBondContact O-N 2.99Å
409	F	88.9	Confident	88.3	Confident	165 Å²	165	45.3 Å²	45.3	72%	0.724	23%	0.233	S	C	*	.	G	3₁₀ helix	trans	-77.4	-5.6	172.8	-61.7	-62	0	0	0	113.7	L406 Y407	L406-F409 HydrophobicContact CD2-CD2 4.49Å; L406-F409 HydrophobicContact CD2-CE2 4.19Å; L406-F409 WeakPolarHBondContact O-CD2 3.47Å; L406-F409 PolarHBondContact O-N 2.82Å; Y407-F409 PolarHBondContact O-N 3.39Å
410	S	85.9	Confident	88.1	Confident	27 Å²	27	43.4 Å²	43.4	19%	0.189	22%	0.224	C	C	.	.			trans	-67.7	144.4	173.2	63.9	0	0	0	0	111.3	Y165 K191 Y407 A408 V416	Y165-S410 WeakPolarHBondContact CE1-OG 3.45Å; K191-S410 WeakPolarHBondContact CE-O 3.45Å; K191-S410 PolarHBondContact NZ-O 3.11Å; Y407-S410 VanDerWaalsContact O-CB 3.24Å; Y407-S410 WeakPolarHBondContact O-CB 3.42Å; Y407-S410 PolarHBondContact O-N 3.42Å; Y407-S410 PolarHBondContact O-OG 2.93Å; A408-S410 PolarHBondContact O-N 2.99Å; S410-V416 WeakPolarHBondContact OG-CG2 3.36Å
411	N	78.6	Confident	87.9	Confident	141 Å²	141	43.2 Å²	43.2	75%	0.754	22%	0.223	S	C	*	.	S	Bend	trans	-90.6	-20.5	-178.3	-63.2	-37.2	0	0	0	113.4
412	D	82.1	Confident	87.6	Confident	74 Å²	74	42.9 Å²	42.9	40%	0.396	22%	0.221	S	C	.	.			trans	-142.7	130.6	-176.6	173.9	31.8	0	0	0	111.1	F414 S415 V416	D412-F414 PolarHBondContact OD1-N 3.15Å; D412-S415 WeakPolarHBondContact O-CB 3.43Å; D412-S415 PolarHBondContact OD2-N 3.47Å; D412-V416 WeakPolarHBondContact O-CG2 3.4Å; D412-V416 PolarHBondContact O-N 2.84Å
413	I	82.4	Confident	87.4	Confident	23 Å²	23	38.4 Å²	38.4	12%	0.118	20%	0.197	C	C	.	.	H	α-helix	trans	-68.3	-35	178.2	-170.1	166.6	0	0	0	112.2	I166 Y169 V170 V416 I417	I166-I413 HydrophobicContact CG1-CG1 4.23Å; I166-I413 HydrophobicContact CG2-CD1 4.01Å; I166-I413 HydrophobicContact CG2-CG1 4.18Å; Y169-I413 HydrophobicContact CD1-CB 4.48Å; Y169-I413 HydrophobicContact CD1-CD1 3.48Å; Y169-I413 VanDerWaalsContact CD1-CD1 3.48Å; Y169-I413 HydrophobicContact CE1-CD1 4.26Å; Y169-I413 HydrophobicContact CG-CD1 4Å; V170-I413 HydrophobicContact CG2-CD1 3.91Å; I413-V416 PolarHBondContact O-N 2.63Å; I413-V416 VanDerWaalsContact O-N 3.16Å; I413-I417 HydrophobicContact CG1-CD1 4.33Å; I413-I417 WeakPolarHBondContact O-CG1 3.22Å; I413-I417 PolarHBondContact O-N 3.49Å
414	F	80.8	Confident	87.2	Confident	42 Å²	42	37.7 Å²	37.7	18%	0.184	19%	0.194	C	C	.	.	H	α-helix	trans	-69.9	-38	179.7	-69.8	-75.6	0	0	0	111.2	R96 D412 V416 I417 N418	R96-F414 VanDerWaalsContact NH1-CE2 3.33Å; D412-F414 PolarHBondContact OD1-N 3.15Å; F414-V416 VanDerWaalsContact C-N 3.31Å; F414-V416 PolarHBondContact O-N 3.33Å; F414-I417 HydrophobicContact CD1-CD1 4.13Å; F414-I417 WeakPolarHBondContact O-CB 3.23Å; F414-I417 PolarHBondContact O-N 2.66Å; F414-I417 VanDerWaalsContact O-N 3.15Å; F414-N418 VanDerWaalsContact O-CG 3.3Å; F414-N418 PolarHBondContact O-N 3.12Å; F414-N418 PolarHBondContact O-ND2 3.46Å
415	S	84.1	Confident	87	Confident	36 Å²	36	38 Å²	38	25%	0.252	20%	0.195	S	C	.	.	H	α-helix	trans	-54.9	-44.2	166.9	-178.2	0	0	0	0	112.3	D412 I417 N418 F419 E477	D412-S415 WeakPolarHBondContact O-CB 3.43Å; D412-S415 PolarHBondContact OD2-N 3.47Å; S415-I417 PolarHBondContact O-N 2.71Å; S415-N418 PolarHBondContact O-N 3.47Å; S415-F419 WeakPolarHBondContact O-CB 3.26Å; S415-F419 PolarHBondContact O-N 3.05Å; S415-E477 WeakPolarHBondContact CB-OE1 3.49Å; S415-E477 VanDerWaalsContact OG-CD 3.26Å; S415-E477 PolarHBondContact OG-OE1 2.79Å
416	V	86.7	Confident	86.9	Confident	7 Å²	7	37.3 Å²	37.3	4%	0.042	19%	0.192	C	C	.	.	H	α-helix	trans	-65.9	-37.8	175.7	-177.2	0	0	0	0	111.9	I166 Y407 S410 D412 I413 F414 F419 F420	I166-V416 HydrophobicContact CD1-CB 4.47Å; I166-V416 HydrophobicContact CD1-CG1 3.88Å; I166-V416 HydrophobicContact CG1-CB 4.26Å; I166-V416 HydrophobicContact CG1-CG1 3.79Å; Y407-V416 HydrophobicContact CD1-CG1 3.88Å; Y407-V416 HydrophobicContact CD1-CG2 4.42Å; Y407-V416 HydrophobicContact CE1-CG1 4.25Å; S410-V416 WeakPolarHBondContact OG-CG2 3.36Å; D412-V416 WeakPolarHBondContact O-CG2 3.4Å; D412-V416 PolarHBondContact O-N 2.84Å; I413-V416 PolarHBondContact O-N 2.63Å; I413-V416 VanDerWaalsContact O-N 3.16Å; F414-V416 VanDerWaalsContact C-N 3.31Å; F414-V416 PolarHBondContact O-N 3.33Å; V416-F419 PolarHBondContact O-N 2.75Å; V416-F420 VanDerWaalsContact O-CB 3.31Å; V416-F420 WeakPolarHBondContact O-CB 3.27Å; V416-F420 PolarHBondContact O-N 2.87Å
417	I	83.9	Confident	86.8	Confident	1 Å²	1	33 Å²	33	1%	0.005	17%	0.169	C	C	.	.	H	α-helix	trans	-63.4	-43.9	174.9	-69.3	165.5	0	0	0	110.9	I166 F272 I413 F414 S415 F420 S421	I166-I417 HydrophobicContact CD1-CB 4.39Å; I166-I417 HydrophobicContact CD1-CG1 3.62Å; I166-I417 HydrophobicContact CG1-CG1 4.03Å; I166-I417 HydrophobicContact CG2-CD1 4.24Å; I166-I417 HydrophobicContact CG2-CG1 4.03Å; F272-I417 HydrophobicContact CB-CG2 4.21Å; F272-I417 HydrophobicContact CD2-CG2 4.27Å; F272-I417 HydrophobicContact CG-CG2 4.19Å; I413-I417 HydrophobicContact CG1-CD1 4.33Å; I413-I417 WeakPolarHBondContact O-CG1 3.22Å; I413-I417 PolarHBondContact O-N 3.49Å; F414-I417 HydrophobicContact CD1-CD1 4.13Å; F414-I417 WeakPolarHBondContact O-CB 3.23Å; F414-I417 PolarHBondContact O-N 2.66Å; F414-I417 VanDerWaalsContact O-N 3.15Å; S415-I417 PolarHBondContact O-N 2.71Å; I417-F420 PolarHBondContact O-N 2.68Å; I417-S421 WeakPolarHBondContact O-CB 3.19Å; I417-S421 PolarHBondContact O-N 3.5Å; I417-S421 PolarHBondContact O-OG 3.24Å
418	N	82.9	Confident	86.7	Confident	23 Å²	23	31.5 Å²	31.5	12%	0.123	16%	0.164	C	C	.	.	H	α-helix	trans	-64.2	-46	177.5	-69.6	-26.3	0	0	0	110.8	F414 S415 S421 F422	F414-N418 VanDerWaalsContact O-CG 3.3Å; F414-N418 PolarHBondContact O-N 3.12Å; F414-N418 PolarHBondContact O-ND2 3.46Å; S415-N418 PolarHBondContact O-N 3.47Å; N418-S421 PolarHBondContact O-N 2.95Å; N418-F422 PolarHBondContact O-N 3.24Å
419	F	85	Confident	86.9	Confident	18 Å²	18	31.1 Å²	31.1	8%	0.079	16%	0.161	C	C	.	.	H	α-helix	trans	-57.4	-50.3	175.3	-174.5	-102.1	0	0	0	111.9	I158 Y407 S415 V416 S421 F423 E477 I484	I158-F419 HydrophobicContact CB-CE1 4.04Å; I158-F419 HydrophobicContact CD1-CE1 4.17Å; I158-F419 HydrophobicContact CD1-CZ 3.9Å; I158-F419 HydrophobicContact CG1-CE1 3.81Å; I158-F419 HydrophobicContact CG1-CZ 3.99Å; I158-F419 HydrophobicContact CG2-CD1 3.78Å; I158-F419 HydrophobicContact CG2-CE1 3.32Å; I158-F419 HydrophobicContact CG2-CZ 4.09Å; Y407-F419 HydrophobicContact CE1-CD1 4.24Å; Y407-F419 HydrophobicContact CE1-CE1 4.35Å; Y407-F419 VanDerWaalsContact OH-CE1 3.3Å; Y407-F419 WeakPolarHBondContact OH-CE1 3.43Å; S415-F419 WeakPolarHBondContact O-CB 3.26Å; S415-F419 PolarHBondContact O-N 3.05Å; V416-F419 PolarHBondContact O-N 2.75Å; F419-S421 PolarHBondContact O-N 3.26Å; F419-F423 HydrophobicContact CD2-CE2 4.01Å; F419-F423 HydrophobicContact CE2-CD2 4.27Å; F419-F423 AromaticContact CE2-CE2 3.61Å; F419-F423 HydrophobicContact CE2-CE2 3.61Å; F419-F423 HydrophobicContact CZ-CD2 4.26Å; F419-F423 AromaticContact CZ-CE2 3.91Å; F419-F423 HydrophobicContact CZ-CE2 3.91Å; F419-F423 VanDerWaalsContact O-CD2 3.27Å; F419-F423 WeakPolarHBondContact O-CD2 3.31Å; F419-E477 HydrophobicContact CD2-CB 4.24Å; F419-E477 WeakPolarHBondContact CD2-O 3.29Å; F419-E477 WeakPolarHBondContact CE2-O 3.41Å; F419-I484 HydrophobicContact CZ-CD1 4.08Å
420	F	88.3	Confident	87.1	Confident	19 Å²	19	26 Å²	26	8%	0.083	14%	0.14	C	C	.	.	H	α-helix	trans	-55.8	-51.5	173.7	164.4	-94	0	0	0	111.8	I159 S162 I166 F272 V416 I417 F422 F423 N424	I159-F420 HydrophobicContact CB-CD2 4.48Å; I159-F420 HydrophobicContact CB-CE2 4.34Å; I159-F420 HydrophobicContact CG2-CD2 4.1Å; I159-F420 HydrophobicContact CG2-CE2 3.49Å; I159-F420 VanDerWaalsContact CG2-CE2 3.49Å; I159-F420 HydrophobicContact CG2-CZ 4.37Å; I159-F420 WeakPolarHBondContact O-CD2 3.11Å; S162-F420 WeakPolarHBondContact OG-CD2 3.3Å; I166-F420 HydrophobicContact CD1-CB 4.42Å; F272-F420 AromaticContact CD2-CD1 3.71Å; F272-F420 HydrophobicContact CD2-CD1 3.71Å; F272-F420 AromaticContact CD2-CE1 3.63Å; F272-F420 HydrophobicContact CD2-CE1 3.63Å; F272-F420 AromaticContact CE2-CD1 3.99Å; F272-F420 HydrophobicContact CE2-CD1 3.99Å; F272-F420 AromaticContact CE2-CE1 3.95Å; F272-F420 HydrophobicContact CE2-CE1 3.95Å; V416-F420 VanDerWaalsContact O-CB 3.31Å; V416-F420 WeakPolarHBondContact O-CB 3.27Å; V416-F420 PolarHBondContact O-N 2.87Å; I417-F420 PolarHBondContact O-N 2.68Å; F420-F422 PolarHBondContact O-N 3.1Å; F420-F423 PolarHBondContact O-N 3.36Å; F420-N424 HydrophobicContact CE1-CB 4.36Å; F420-N424 HydrophobicContact CZ-CB 4.29Å; F420-N424 WeakPolarHBondContact O-CB 3.37Å; F420-N424 PolarHBondContact O-N 3.06Å
421	S	86.9	Confident	87.4	Confident	1 Å²	1	24.9 Å²	24.9	1%	0.007	13%	0.132	C	C	.	.	H	α-helix	trans	-62.6	-44.6	-171.5	-64.4	0	0	0	0	111	I417 N418 F419 F423 N424 W425	I417-S421 WeakPolarHBondContact O-CB 3.19Å; I417-S421 PolarHBondContact O-N 3.5Å; I417-S421 PolarHBondContact O-OG 3.24Å; N418-S421 PolarHBondContact O-N 2.95Å; F419-S421 PolarHBondContact O-N 3.26Å; S421-F423 PolarHBondContact O-N 2.83Å; S421-N424 PolarHBondContact O-N 3.1Å; S421-W425 WeakPolarHBondContact O-CB 3.47Å; S421-W425 PolarHBondContact O-N 3.47Å
422	F	87.9	Confident	88.1	Confident	2 Å²	2	18.2 Å²	18.2	1%	0.009	10%	0.096	C	C	.	.	H	α-helix	trans	-52.8	-54.2	178.8	179	-94.4	0	0	0	112.5	N418 F420 W425 L426 I467 S470 F471 C478 F482	N418-F422 PolarHBondContact O-N 3.24Å; F420-F422 PolarHBondContact O-N 3.1Å; F422-W425 PolarHBondContact O-N 2.88Å; F422-L426 WeakPolarHBondContact O-CB 3.48Å; F422-L426 PolarHBondContact O-N 3.25Å; F422-I467 HydrophobicContact CD2-CG2 4.5Å; F422-I467 HydrophobicContact CE2-CB 4.34Å; F422-I467 HydrophobicContact CE2-CG2 3.66Å; F422-I467 HydrophobicContact CZ-CG2 4.11Å; F422-S470 VanDerWaalsContact CD2-CB 3.45Å; F422-F471 AromaticContact CE2-CD2 3.91Å; F422-F471 HydrophobicContact CE2-CD2 3.91Å; F422-F471 AromaticContact CE2-CE2 3.71Å; F422-F471 HydrophobicContact CE2-CE2 3.71Å; F422-F471 HydrophobicContact CE2-CZ 4.22Å; F422-F471 HydrophobicContact CZ-CD2 4.23Å; F422-F471 HydrophobicContact CZ-CE1 4.36Å; F422-F471 AromaticContact CZ-CE2 3.59Å; F422-F471 HydrophobicContact CZ-CE2 3.59Å; F422-F471 AromaticContact CZ-CZ 3.71Å; F422-F471 HydrophobicContact CZ-CZ 3.71Å; F422-C478 HydrophobicContact CZ-CB 4.48Å; F422-F482 AromaticContact CE1-CE2 3.58Å; F422-F482 HydrophobicContact CE1-CE2 3.58Å; F422-F482 AromaticContact CE1-CZ 3.69Å; F422-F482 HydrophobicContact CE1-CZ 3.69Å; F422-F482 AromaticContact CZ-CE2 3.52Å; F422-F482 HydrophobicContact CZ-CE2 3.52Å; F422-F482 AromaticContact CZ-CZ 3.66Å; F422-F482 HydrophobicContact CZ-CZ 3.66Å
423	F	90.1	Very high	88.7	Confident	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-71.6	-34.1	-177.3	-71.4	-68	0	0	0	112.8	I154 I158 F419 F420 S421 L426 C427 I485	I154-F423 HydrophobicContact CG2-CB 3.83Å; I154-F423 HydrophobicContact CG2-CD1 4.44Å; I154-F423 HydrophobicContact CG2-CG 4.34Å; I158-F423 HydrophobicContact CD1-CD1 4.37Å; I158-F423 HydrophobicContact CD1-CD2 3.88Å; I158-F423 HydrophobicContact CD1-CE2 4.13Å; I158-F423 HydrophobicContact CD1-CG 4.05Å; I158-F423 HydrophobicContact CG2-CB 4.1Å; I158-F423 HydrophobicContact CG2-CD2 3.78Å; I158-F423 HydrophobicContact CG2-CG 4.17Å; F419-F423 HydrophobicContact CD2-CE2 4.01Å; F419-F423 HydrophobicContact CE2-CD2 4.27Å; F419-F423 AromaticContact CE2-CE2 3.61Å; F419-F423 HydrophobicContact CE2-CE2 3.61Å; F419-F423 HydrophobicContact CZ-CD2 4.26Å; F419-F423 AromaticContact CZ-CE2 3.91Å; F419-F423 HydrophobicContact CZ-CE2 3.91Å; F419-F423 VanDerWaalsContact O-CD2 3.27Å; F419-F423 WeakPolarHBondContact O-CD2 3.31Å; F420-F423 PolarHBondContact O-N 3.36Å; S421-F423 PolarHBondContact O-N 2.83Å; F423-L426 HydrophobicContact CD1-CD2 4.24Å; F423-L426 PolarHBondContact O-N 2.9Å; F423-C427 WeakPolarHBondContact O-CB 3.5Å; F423-C427 PolarHBondContact O-N 3.47Å; F423-C427 PolarHBondContact O-SG 3.03Å; F423-C427 VanDerWaalsContact O-SG 3.36Å; F423-I485 HydrophobicContact CD1-CD1 3.66Å; F423-I485 HydrophobicContact CE1-CD1 3.35Å; F423-I485 HydrophobicContact CE1-CG1 4.25Å; F423-I485 HydrophobicContact CZ-CD1 4.46Å
424	N	90.2	Very high	89.1	Confident	22 Å²	22	16.4 Å²	16.4	12%	0.118	9%	0.089	C	C	.	.	H	α-helix	trans	-61.7	-48	174	-172.9	55.4	0	0	0	111.1	F420 S421 L426 C427 I428	F420-N424 HydrophobicContact CE1-CB 4.36Å; F420-N424 HydrophobicContact CZ-CB 4.29Å; F420-N424 WeakPolarHBondContact O-CB 3.37Å; F420-N424 PolarHBondContact O-N 3.06Å; S421-N424 PolarHBondContact O-N 3.1Å; N424-L426 PolarHBondContact O-N 3.09Å; N424-C427 PolarHBondContact O-N 3.02Å; N424-I428 WeakPolarHBondContact O-CB 3.48Å; N424-I428 VanDerWaalsContact O-CG1 3.31Å; N424-I428 WeakPolarHBondContact O-CG1 3.32Å; N424-I428 PolarHBondContact O-N 3.39Å
425	W	90.5	Very high	89.6	Confident	5 Å²	5	14.4 Å²	14.4	2%	0.019	8%	0.08	C	C	.	.	H	α-helix	trans	-67.9	-33.8	178.4	-70.4	115.2	0	0	0	113	F114 Y268 L271 W277 S421 F422 I428 A429 F459 L466	F114-W425 HydrophobicContact CD1-CH2 4.24Å; F114-W425 HydrophobicContact CD1-CZ3 4.48Å; F114-W425 HydrophobicContact CE1-CE3 4.12Å; F114-W425 AromaticContact CE1-CH2 3.53Å; F114-W425 HydrophobicContact CE1-CH2 3.53Å; F114-W425 HydrophobicContact CE1-CZ2 4.25Å; F114-W425 AromaticContact CE1-CZ3 3.43Å; F114-W425 HydrophobicContact CE1-CZ3 3.43Å; F114-W425 VanDerWaalsContact CE1-CZ3 3.43Å; F114-W425 HydrophobicContact CZ-CE3 4.38Å; F114-W425 HydrophobicContact CZ-CH2 4.5Å; F114-W425 AromaticContact CZ-CZ3 3.99Å; F114-W425 HydrophobicContact CZ-CZ3 3.99Å; Y268-W425 AromaticContact CD1-CD1 3.85Å; Y268-W425 AromaticContact CD1-NE1 3.96Å; Y268-W425 AromaticContact CE1-CD1 3.51Å; Y268-W425 HydrophobicContact CE1-CG 4.41Å; L271-W425 HydrophobicContact CB-CZ2 3.74Å; L271-W425 HydrophobicContact CD1-CH2 4.36Å; L271-W425 HydrophobicContact CD1-CZ2 3.76Å; L271-W425 HydrophobicContact CD2-CH2 4.35Å; L271-W425 HydrophobicContact CD2-CZ2 4.15Å; L271-W425 HydrophobicContact CG-CZ2 4.08Å; W277-W425 HydrophobicContact CZ2-CH2 4.35Å; W277-W425 HydrophobicContact CZ2-CZ3 4.43Å; S421-W425 WeakPolarHBondContact O-CB 3.47Å; S421-W425 PolarHBondContact O-N 3.47Å; F422-W425 PolarHBondContact O-N 2.88Å; W425-I428 HydrophobicContact CE3-CB 4.4Å; W425-I428 HydrophobicContact CE3-CD1 4.09Å; W425-I428 HydrophobicContact CE3-CG2 4.15Å; W425-I428 HydrophobicContact CH2-CD1 4.38Å; W425-I428 HydrophobicContact CZ3-CD1 3.95Å; W425-I428 HydrophobicContact CZ3-CG2 4.1Å; W425-A429 VanDerWaalsContact O-CB 3.24Å; W425-A429 WeakPolarHBondContact O-CB 3.39Å; W425-A429 PolarHBondContact O-N 3.26Å; W425-F459 HydrophobicContact CZ3-CE1 4.46Å; W425-F459 HydrophobicContact CZ3-CE2 4.5Å; W425-F459 AromaticContact CZ3-CZ 3.78Å; W425-F459 HydrophobicContact CZ3-CZ 3.78Å; W425-L466 HydrophobicContact CD2-CD1 4.38Å; W425-L466 HydrophobicContact CG-CD1 4.45Å
426	L	91.9	Very high	90	Very high	35 Å²	35	14.5 Å²	14.5	18%	0.183	8%	0.077	C	C	.	.	H	α-helix	trans	-60.6	-50.4	171.6	-176.7	70.7	0	0	0	111.5	F422 F423 N424 A429 M430 I467 I485	F422-L426 WeakPolarHBondContact O-CB 3.48Å; F422-L426 PolarHBondContact O-N 3.25Å; F423-L426 HydrophobicContact CD1-CD2 4.24Å; F423-L426 PolarHBondContact O-N 2.9Å; N424-L426 PolarHBondContact O-N 3.09Å; L426-A429 PolarHBondContact O-N 3.49Å; L426-M430 WeakPolarHBondContact O-CG 3.49Å; L426-M430 PolarHBondContact O-N 3.09Å; L426-I467 HydrophobicContact CB-CD1 4.34Å; L426-I467 HydrophobicContact CD1-CD1 4.15Å; L426-I485 HydrophobicContact CD2-CD1 4.49Å
427	C	91.8	Very high	90.3	Very high	3 Å²	3	19.2 Å²	19.2	2%	0.02	10%	0.095	C	C	.	.	H	α-helix	trans	-62.1	-43.8	178.7	-73.6	0	0	0	0	112.2	F423 N424 M430 A431	F423-C427 WeakPolarHBondContact O-CB 3.5Å; F423-C427 PolarHBondContact O-N 3.47Å; F423-C427 PolarHBondContact O-SG 3.03Å; F423-C427 VanDerWaalsContact O-SG 3.36Å; N424-C427 PolarHBondContact O-N 3.02Å; C427-M430 PolarHBondContact O-N 3.46Å; C427-A431 PolarHBondContact O-N 3.42Å
428	I	91.6	Very high	90.6	Very high	3 Å²	3	19.3 Å²	19.3	2%	0.015	10%	0.095	C	C	.	.	H	α-helix	trans	-62.7	-44	177	-74.6	169.9	0	0	0	111.2	Y122 W277 N424 W425 M430 A431 I432 F459	Y122-I428 HydrophobicContact CE2-CG2 4.18Å; W277-I428 HydrophobicContact CH2-CD1 4.42Å; W277-I428 HydrophobicContact CH2-CG2 4.37Å; W277-I428 HydrophobicContact CZ2-CD1 4.15Å; N424-I428 WeakPolarHBondContact O-CB 3.48Å; N424-I428 VanDerWaalsContact O-CG1 3.31Å; N424-I428 WeakPolarHBondContact O-CG1 3.32Å; N424-I428 PolarHBondContact O-N 3.39Å; W425-I428 HydrophobicContact CE3-CB 4.4Å; W425-I428 HydrophobicContact CE3-CD1 4.09Å; W425-I428 HydrophobicContact CE3-CG2 4.15Å; W425-I428 HydrophobicContact CH2-CD1 4.38Å; W425-I428 HydrophobicContact CZ3-CD1 3.95Å; W425-I428 HydrophobicContact CZ3-CG2 4.1Å; I428-M430 PolarHBondContact O-N 2.94Å; I428-A431 PolarHBondContact O-N 3.31Å; I428-I432 HydrophobicContact CG2-CD1 4.16Å; I428-I432 PolarHBondContact O-N 3.21Å; I428-I432 VanDerWaalsContact O-N 3.12Å; I428-F459 HydrophobicContact CG2-CE1 3.56Å; I428-F459 HydrophobicContact CG2-CZ 4.02Å
429	A	93.8	Very high	90.9	Very high	7 Å²	7	20 Å²	20	6%	0.058	10%	0.096	C	C	.	.	H	α-helix	trans	-61.4	-44.9	177	0	0	0	0	0	111.2	W425 L426 A431 I432 V433 C463	W425-A429 VanDerWaalsContact O-CB 3.24Å; W425-A429 WeakPolarHBondContact O-CB 3.39Å; W425-A429 PolarHBondContact O-N 3.26Å; L426-A429 PolarHBondContact O-N 3.49Å; A429-A431 PolarHBondContact O-N 3.19Å; A429-I432 PolarHBondContact O-N 2.73Å; A429-V433 WeakPolarHBondContact O-CB 3.43Å; A429-V433 VanDerWaalsContact O-CG2 3.26Å; A429-V433 WeakPolarHBondContact O-CG2 3.44Å; A429-V433 PolarHBondContact O-N 2.81Å; A429-C463 HydrophobicContact CB-CB 3.87Å
430	M	93.4	Very high	91.1	Very high	57 Å²	57	28.9 Å²	28.9	28%	0.281	13%	0.13	S	C	.	.	H	α-helix	trans	-60.1	-43	175.7	-72.1	-165.7	-62.1	0	0	112.2	Y143 L426 C427 I428 I432 V433 G434	Y143-M430 WeakPolarHBondContact CE2-O 3.46Å; Y143-M430 PolarHBondContact OH-O 3.39Å; Y143-M430 VanDerWaalsContact OH-O 3.11Å; L426-M430 WeakPolarHBondContact O-CG 3.49Å; L426-M430 PolarHBondContact O-N 3.09Å; C427-M430 PolarHBondContact O-N 3.46Å; I428-M430 PolarHBondContact O-N 2.94Å; M430-I432 VanDerWaalsContact C-N 3.34Å; M430-I432 PolarHBondContact O-N 3.3Å; M430-V433 PolarHBondContact O-N 2.87Å; M430-G434 PolarHBondContact O-N 3.06Å
431	A	92.3	Very high	91.2	Very high	3 Å²	3	34.2 Å²	34.2	3%	0.025	15%	0.153	C	C	.	.	H	α-helix	trans	-60.6	-42.3	178.1	0	0	0	0	0	112.3	Y122 L125 C427 I428 A429 G434 M435	Y122-A431 WeakPolarHBondContact OH-CB 3.3Å; L125-A431 HydrophobicContact CD2-CB 4.42Å; C427-A431 PolarHBondContact O-N 3.42Å; I428-A431 PolarHBondContact O-N 3.31Å; A429-A431 PolarHBondContact O-N 3.19Å; A431-G434 PolarHBondContact O-N 3.42Å; A431-M435 PolarHBondContact O-N 3.45Å
432	I	93.3	Very high	91.3	Very high	1 Å²	1	38.4 Å²	38.4	1%	0.005	17%	0.172	C	C	.	.	H	α-helix	trans	-77.5	-35.3	-178.6	-64.6	170.7	0	0	0	112	C121 Y122 I428 A429 M430 G434 M435 M436 P456 F459 V460	C121-I432 HydrophobicContact CB-CD1 4.08Å; C121-I432 HydrophobicContact CB-CG1 4.31Å; Y122-I432 HydrophobicContact CD2-CD1 4.16Å; Y122-I432 HydrophobicContact CD2-CG1 4.25Å; Y122-I432 HydrophobicContact CE2-CD1 3.98Å; Y122-I432 HydrophobicContact CE2-CG1 3.97Å; I428-I432 HydrophobicContact CG2-CD1 4.16Å; I428-I432 PolarHBondContact O-N 3.21Å; I428-I432 VanDerWaalsContact O-N 3.12Å; A429-I432 PolarHBondContact O-N 2.73Å; M430-I432 VanDerWaalsContact C-N 3.34Å; M430-I432 PolarHBondContact O-N 3.3Å; I432-G434 PolarHBondContact O-N 3.27Å; I432-M435 WeakPolarHBondContact O-CB 3.42Å; I432-M435 PolarHBondContact O-N 3.46Å; I432-M436 PolarHBondContact O-N 3.35Å; I432-P456 HydrophobicContact CG2-CB 3.86Å; I432-F459 HydrophobicContact CD1-CD1 3.18Å; I432-F459 HydrophobicContact CD1-CE1 3.17Å; I432-F459 HydrophobicContact CD1-CG 4.27Å; I432-F459 HydrophobicContact CD1-CZ 4.26Å; I432-V460 HydrophobicContact CB-CG2 4.01Å; I432-V460 HydrophobicContact CG2-CG2 3.64Å
433	V	94.6	Very high	91.3	Very high	58 Å²	58	42.7 Å²	42.7	35%	0.352	20%	0.2	S	C	.	.	H	α-helix	trans	-58.9	-41.4	167.8	172	0	0	0	0	109.8	A429 M430 M435 M436 W437 V460	A429-V433 WeakPolarHBondContact O-CB 3.43Å; A429-V433 VanDerWaalsContact O-CG2 3.26Å; A429-V433 WeakPolarHBondContact O-CG2 3.44Å; A429-V433 PolarHBondContact O-N 2.81Å; M430-V433 PolarHBondContact O-N 2.87Å; V433-M435 VanDerWaalsContact C-N 3.34Å; V433-M435 PolarHBondContact O-N 3Å; V433-M436 HydrophobicContact CG2-CE 4.13Å; V433-M436 PolarHBondContact O-N 2.96Å; V433-W437 WeakPolarHBondContact O-CB 3.46Å; V433-W437 PolarHBondContact O-N 3.22Å; V433-V460 HydrophobicContact CG2-CG1 3.81Å; V433-V460 HydrophobicContact CG2-CG2 4.01Å
434	G	91.7	Very high	91.1	Very high	1 Å²	1	51.5 Å²	51.5	1%	0.01	24%	0.241	C	C	.	.	H	α-helix	trans	-61.5	-40.7	174.6	0	0	0	0	0	113	Y143 M430 A431 I432 W437 L438	Y143-G434 WeakPolarHBondContact OH-CA 2.89Å; Y143-G434 PolarHBondContact OH-N 3.13Å; Y143-G434 VanDerWaalsContact OH-N 3.09Å; M430-G434 PolarHBondContact O-N 3.06Å; A431-G434 PolarHBondContact O-N 3.42Å; I432-G434 PolarHBondContact O-N 3.27Å; G434-W437 PolarHBondContact O-N 3.39Å; G434-L438 WeakPolarHBondContact O-CB 3.28Å; G434-L438 PolarHBondContact O-N 3.49Å
435	M	91.4	Very high	90.9	Very high	0 Å²	0	53.8 Å²	53.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-60	-45.1	173.4	-177.4	-108.2	-106.9	0	0	112.3	C121 E124 L125 A431 I432 V433 L438 R439 V451 P456	C121-M435 HydrophobicContact CB-CE 3.79Å; C121-M435 WeakPolarHBondContact O-CE 3.16Å; E124-M435 HydrophobicContact CB-CE 4.02Å; E124-M435 HydrophobicContact CG-CE 4.04Å; L125-M435 HydrophobicContact CD1-CB 3.89Å; L125-M435 HydrophobicContact CD1-CG 4.05Å; A431-M435 PolarHBondContact O-N 3.45Å; I432-M435 WeakPolarHBondContact O-CB 3.42Å; I432-M435 PolarHBondContact O-N 3.46Å; V433-M435 VanDerWaalsContact C-N 3.34Å; V433-M435 PolarHBondContact O-N 3Å; M435-L438 WeakPolarHBondContact O-CB 3.42Å; M435-L438 PolarHBondContact O-N 3.5Å; M435-R439 PolarHBondContact O-N 3.06Å; M435-R439 VanDerWaalsContact O-N 3.15Å; M435-V451 HydrophobicContact CE-CG2 4.35Å; M435-P456 HydrophobicContact CE-CG 4.06Å; M435-P456 HydrophobicContact SD-CG 4.16Å
436	M	92.3	Very high	90.7	Very high	39 Å²	39	61.7 Å²	61.7	19%	0.192	29%	0.29	C	S	.	.	H	α-helix	trans	-65.1	-41.1	176.1	-69.6	-171.7	-68.7	0	0	111.9	I432 V433 L438 R439 Y440 I453 P456 V457 V460	I432-M436 PolarHBondContact O-N 3.35Å; V433-M436 HydrophobicContact CG2-CE 4.13Å; V433-M436 PolarHBondContact O-N 2.96Å; M436-L438 VanDerWaalsContact C-N 3.33Å; M436-L438 PolarHBondContact O-N 2.7Å; M436-R439 WeakPolarHBondContact O-CB 3.3Å; M436-R439 PolarHBondContact O-N 2.89Å; M436-Y440 PolarHBondContact O-N 3.19Å; M436-I453 HydrophobicContact CG-CD1 4.08Å; M436-I453 HydrophobicContact SD-CD1 4.3Å; M436-P456 HydrophobicContact CG-CB 3.83Å; M436-P456 HydrophobicContact SD-CB 3.78Å; M436-V457 HydrophobicContact SD-CG2 3.76Å; M436-V460 HydrophobicContact CE-CB 4.27Å; M436-V460 HydrophobicContact CE-CG2 3.73Å
437	W	92.6	Very high	90.4	Very high	106 Å²	106	62 Å²	62	40%	0.402	29%	0.289	S	S	.	.	H	α-helix	trans	-64	-38.9	175.8	-175.2	85.7	0	0	0	112.1	V142 V433 G434 R439 Y440 K441	V142-W437 HydrophobicContact CG1-CE3 3.66Å; V142-W437 HydrophobicContact CG1-CZ3 3.95Å; V433-W437 WeakPolarHBondContact O-CB 3.46Å; V433-W437 PolarHBondContact O-N 3.22Å; G434-W437 PolarHBondContact O-N 3.39Å; W437-R439 VanDerWaalsContact C-N 3.26Å; W437-R439 PolarHBondContact O-N 3.49Å; W437-Y440 PolarHBondContact O-N 3.01Å; W437-Y440 VanDerWaalsContact O-N 3.12Å; W437-K441 HydrophobicContact CD2-CB 4.43Å; W437-K441 HydrophobicContact CD2-CD 4.41Å; W437-K441 HydrophobicContact CE3-CB 4.46Å; W437-K441 HydrophobicContact CE3-CD 4.37Å; W437-K441 HydrophobicContact CH2-CD 3.28Å; W437-K441 HydrophobicContact CZ2-CD 3.22Å; W437-K441 HydrophobicContact CZ3-CD 3.85Å; W437-K441 PolarHBondContact O-N 3.43Å
438	L	90	Very high	90	Very high	3 Å²	3	64.7 Å²	64.7	2%	0.016	31%	0.306	C	S	.	.	H	α-helix	trans	-61.9	-34.6	175	-166.7	70.2	0	0	0	111.6	T128 I129 G434 M435 M436 Y440 K442 L445 R447	T128-L438 HydrophobicContact CG2-CD2 4.18Å; I129-L438 HydrophobicContact CD1-CD2 4.35Å; G434-L438 WeakPolarHBondContact O-CB 3.28Å; G434-L438 PolarHBondContact O-N 3.49Å; M435-L438 WeakPolarHBondContact O-CB 3.42Å; M435-L438 PolarHBondContact O-N 3.5Å; M436-L438 VanDerWaalsContact C-N 3.33Å; M436-L438 PolarHBondContact O-N 2.7Å; L438-Y440 VanDerWaalsContact C-N 3.28Å; L438-Y440 PolarHBondContact O-N 3.36Å; L438-K442 HydrophobicContact CD1-CB 4.12Å; L438-K442 HydrophobicContact CD1-CD 3.9Å; L438-K442 HydrophobicContact CD1-CG 4.29Å; L438-K442 CarbonylContact O-C 3.57Å; L438-K442 PolarHBondContact O-N 3.49Å; L438-L445 HydrophobicContact CD1-CD1 3.72Å; L438-L445 HydrophobicContact CD2-CD1 3.92Å; L438-L445 HydrophobicContact CG-CD1 3.81Å; L438-R447 PolarHBondContact O-NH2 3.43Å; L438-R447 VanDerWaalsContact O-NH2 3.14Å
439	R	89.5	Confident	89.8	Confident	38 Å²	38	65.8 Å²	65.8	14%	0.143	31%	0.311	C	S	.	.	H	α-helix	trans	-62.4	-37.3	175.3	-73	178.1	173.1	-163	2	112.1	E124 M435 M436 W437 R447 V451 I453	E124-R439 IonicContact OE1-CZ 3.58Å; E124-R439 IonicContact OE1-NE 2.98Å; E124-R439 PolarHBondContact OE1-NE 3.29Å; E124-R439 IonicContact OE1-NH2 3.33Å; E124-R439 PolarHBondContact OE1-NH2 3.24Å; E124-R439 IonicContact OE2-CZ 2.93Å; E124-R439 IonicContact OE2-NE 2.6Å; E124-R439 IonicContact OE2-NH2 3.67Å; E124-R439 PolarHBondContact OE2-NH2 3.44Å; M435-R439 PolarHBondContact O-N 3.06Å; M435-R439 VanDerWaalsContact O-N 3.15Å; M436-R439 WeakPolarHBondContact O-CB 3.3Å; M436-R439 PolarHBondContact O-N 2.89Å; W437-R439 VanDerWaalsContact C-N 3.26Å; W437-R439 PolarHBondContact O-N 3.49Å; R439-R447 VanDerWaalsContact CA-NH2 3.26Å; R439-R447 VanDerWaalsContact CG-CZ 3.46Å; R439-V451 PolarHBondContact NH1-O 3.45Å; R439-V451 PolarHBondContact NH2-O 2.99Å; R439-I453 VanDerWaalsContact NH1-CD1 3.32Å
440	Y	88.8	Confident	89.4	Confident	204 Å²	204	73 Å²	73	80%	0.8	34%	0.341	S	S	*	.	H	α-helix	trans	-79.2	-46.8	-178.8	-176.4	-102.5	0	0	0	112	M436 W437 L438	M436-Y440 PolarHBondContact O-N 3.19Å; W437-Y440 PolarHBondContact O-N 3.01Å; W437-Y440 VanDerWaalsContact O-N 3.12Å; L438-Y440 VanDerWaalsContact C-N 3.28Å; L438-Y440 PolarHBondContact O-N 3.36Å
441	K	90.8	Very high	89.3	Confident	130 Å²	130	71.1 Å²	71.1	57%	0.565	33%	0.333	S	S	*	.	H	α-helix	trans	-84.3	-31.4	-171.7	-166.8	173.4	-178.3	-179.5	0	114.3	W437	W437-K441 HydrophobicContact CD2-CB 4.43Å; W437-K441 HydrophobicContact CD2-CD 4.41Å; W437-K441 HydrophobicContact CE3-CB 4.46Å; W437-K441 HydrophobicContact CE3-CD 4.37Å; W437-K441 HydrophobicContact CH2-CD 3.28Å; W437-K441 HydrophobicContact CZ2-CD 3.22Å; W437-K441 HydrophobicContact CZ3-CD 3.85Å; W437-K441 PolarHBondContact O-N 3.43Å
442	K	89.8	Confident	89.3	Confident	90 Å²	90	75.8 Å²	75.8	39%	0.391	36%	0.358	S	S	.	.			trans	-128.3	71.4	179.6	-66.1	-173.4	-178	177.1	0	109.9	E141 L438 E444 L445	E141-K442 IonicContact OE1-NZ 2.87Å; L438-K442 HydrophobicContact CD1-CB 4.12Å; L438-K442 HydrophobicContact CD1-CD 3.9Å; L438-K442 HydrophobicContact CD1-CG 4.29Å; L438-K442 CarbonylContact O-C 3.57Å; L438-K442 PolarHBondContact O-N 3.49Å; K442-E444 PolarHBondContact O-N 2.95Å; K442-L445 HydrophobicContact CB-CD1 3.53Å; K442-L445 HydrophobicContact CB-CG 3.97Å; K442-L445 HydrophobicContact CD-CD1 3.78Å; K442-L445 HydrophobicContact CD-CG 4.42Å; K442-L445 HydrophobicContact CG-CD1 4.32Å
443	P	86.6	Confident	89.2	Confident	92 Å²	92	79.2 Å²	79.2	60%	0.597	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-22.1	-178	29.4	-34.9	0	0	0	113.1	L445	P443-L445 VanDerWaalsContact C-N 3.31Å; P443-L445 PolarHBondContact O-N 3.49Å
444	E	87.2	Confident	89.1	Confident	185 Å²	185	82 Å²	82	86%	0.864	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.4	-11.5	-177.5	-58.6	-176.6	-179.9	0	0	114	K442 E446	K442-E444 PolarHBondContact O-N 2.95Å; E444-E446 PolarHBondContact O-N 3.33Å
445	L	85.5	Confident	89.1	Confident	70 Å²	70	84.8 Å²	84.8	37%	0.366	40%	0.402	S	S	.	.	S	Bend	trans	-60.9	129	175.3	-76.8	167.5	0	0	0	109.9	L438 K442 P443 R447	L438-L445 HydrophobicContact CD1-CD1 3.72Å; L438-L445 HydrophobicContact CD2-CD1 3.92Å; L438-L445 HydrophobicContact CG-CD1 3.81Å; K442-L445 HydrophobicContact CB-CD1 3.53Å; K442-L445 HydrophobicContact CB-CG 3.97Å; K442-L445 HydrophobicContact CD-CD1 3.78Å; K442-L445 HydrophobicContact CD-CG 4.42Å; K442-L445 HydrophobicContact CG-CD1 4.32Å; P443-L445 VanDerWaalsContact C-N 3.31Å; P443-L445 PolarHBondContact O-N 3.49Å; L445-R447 PolarHBondContact O-N 3.46Å
446	E	85.1	Confident	89.2	Confident	171 Å²	171	84.8 Å²	84.8	80%	0.799	40%	0.402	S	S	*	.			trans	-59.6	121.1	173.4	-68.8	-171.8	174.1	0	0	109.7	E444 P448	E444-E446 PolarHBondContact O-N 3.33Å; E446-P448 WeakPolarHBondContact O-CD 3.35Å
447	R	85.9	Confident	89.3	Confident	42 Å²	42	85.8 Å²	85.8	16%	0.158	41%	0.41	C	S	.	.			trans	-119	90.8	177.9	-69.6	170.8	-172	-99.7	-7.1	108.5	E124 T128 L438 R439 L445 I449	E124-R447 IonicContact OE1-NH1 2.76Å; E124-R447 PolarHBondContact OE1-NH1 3.1Å; T128-R447 HydrophobicContact CG2-CG 4.13Å; L438-R447 PolarHBondContact O-NH2 3.43Å; L438-R447 VanDerWaalsContact O-NH2 3.14Å; R439-R447 VanDerWaalsContact CA-NH2 3.26Å; R439-R447 VanDerWaalsContact CG-CZ 3.46Å; L445-R447 PolarHBondContact O-N 3.46Å; R447-I449 PolarHBondContact O-N 2.85Å
448	P	84.4	Confident	89.3	Confident	59 Å²	59	83.5 Å²	83.5	38%	0.383	41%	0.41	S	S	.	.	S	Bend	trans	-60.2	-31.2	-179.5	-26.9	38	0	0	0	112.4	Y291 E446	Y291-P448 HydrophobicContact CD1-CB 3.44Å; Y291-P448 VanDerWaalsContact CD1-CB 3.44Å; Y291-P448 HydrophobicContact CD1-CG 3.63Å; Y291-P448 HydrophobicContact CD2-CB 4.32Å; Y291-P448 HydrophobicContact CE1-CB 3.87Å; Y291-P448 HydrophobicContact CE1-CG 3.47Å; Y291-P448 VanDerWaalsContact CE1-CG 3.47Å; Y291-P448 HydrophobicContact CE2-CG 4.37Å; Y291-P448 HydrophobicContact CG-CB 3.71Å; Y291-P448 HydrophobicContact CG-CG 4.19Å; E446-P448 WeakPolarHBondContact O-CD 3.35Å
449	I	86	Confident	89.4	Confident	25 Å²	25	83.5 Å²	83.5	13%	0.128	41%	0.41	C	S	.	.	S	Bend	trans	-117.9	128.3	172.3	-56.4	177.6	0	0	0	108.1	E124 T127 P295 R447 V451	E124-I449 HydrophobicContact CB-CG2 4.46Å; E124-I449 VanDerWaalsContact CG-O 3.29Å; E124-I449 WeakPolarHBondContact CG-O 3.43Å; T127-I449 HydrophobicContact CG2-CD1 3.58Å; T127-I449 HydrophobicContact CG2-CG1 4.12Å; P295-I449 HydrophobicContact CB-CD1 4.11Å; P295-I449 HydrophobicContact CG-CD1 3.63Å; R447-I449 PolarHBondContact O-N 2.85Å; I449-V451 HydrophobicContact CG2-CG1 4.47Å
450	K	87.3	Confident	89.7	Confident	159 Å²	159	82.3 Å²	82.3	69%	0.691	41%	0.407	S	S	*	.			trans	-131	109.7	174.8	-172.7	177.7	-179.4	178.5	0	109.6	E124	E124-K450 WeakPolarHBondContact OE2-CA 3.39Å
451	V	90.7	Very high	89.9	Confident	18 Å²	18	77.8 Å²	77.8	11%	0.109	40%	0.396	C	S	.	.			trans	-82.7	154.9	176.1	-59.4	0	0	0	0	111.1	L120 E124 M435 R439 I449 I453 L455 P456	L120-V451 HydrophobicContact CB-CG1 4.33Å; E124-V451 WeakPolarHBondContact OE2-CG2 3.1Å; E124-V451 PolarHBondContact OE2-N 3.31Å; M435-V451 HydrophobicContact CE-CG2 4.35Å; R439-V451 PolarHBondContact NH1-O 3.45Å; R439-V451 PolarHBondContact NH2-O 2.99Å; I449-V451 HydrophobicContact CG2-CG1 4.47Å; V451-I453 PolarHBondContact O-N 3.16Å; V451-L455 HydrophobicContact CB-CD1 4.39Å; V451-P456 HydrophobicContact CG2-CG 3.93Å
452	N	92.8	Very high	89.9	Confident	101 Å²	101	73.1 Å²	73.1	54%	0.54	38%	0.382	S	S	.	.			trans	-60.2	136.1	174.7	-169.4	-1.8	0	0	0	110.1	L454 L455 P456	N452-L454 PolarHBondContact O-N 3.34Å; N452-L454 VanDerWaalsContact O-N 3.14Å; N452-L455 WeakPolarHBondContact O-CB 3.36Å; N452-L455 PolarHBondContact O-N 3.33Å; N452-P456 WeakPolarHBondContact O-CD 3.31Å
453	I	90.3	Very high	90	Very high	72 Å²	72	68.8 Å²	68.8	37%	0.369	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-26	-175	-167.6	64.6	0	0	0	113.1	M436 R439 V451 L455 P456 V457	M436-I453 HydrophobicContact CG-CD1 4.08Å; M436-I453 HydrophobicContact SD-CD1 4.3Å; R439-I453 VanDerWaalsContact NH1-CD1 3.32Å; V451-I453 PolarHBondContact O-N 3.16Å; I453-L455 PolarHBondContact O-N 3.44Å; I453-P456 WeakPolarHBondContact O-CD 3.5Å; I453-V457 HydrophobicContact CG1-CG2 4.24Å; I453-V457 VanDerWaalsContact O-CG2 3.3Å; I453-V457 WeakPolarHBondContact O-CG2 3.27Å; I453-V457 PolarHBondContact O-N 3.37Å; I453-V457 VanDerWaalsContact O-N 3.17Å
454	L	92.2	Very high	90.3	Very high	118 Å²	118	68.2 Å²	68.2	62%	0.618	36%	0.355	S	S	*	.	H	α-helix	trans	-59.5	-30.6	175.1	-62.8	176.6	0	0	0	112.5	N452 S458	N452-L454 PolarHBondContact O-N 3.34Å; N452-L454 VanDerWaalsContact O-N 3.14Å; L454-S458 VanDerWaalsContact O-CB 3.29Å; L454-S458 WeakPolarHBondContact O-CB 3.43Å; L454-S458 PolarHBondContact O-N 3.14Å; L454-S458 PolarHBondContact O-OG 3.11Å
455	L	92.1	Very high	90.3	Very high	59 Å²	59	63.1 Å²	63.1	31%	0.309	33%	0.33	S	S	.	.	H	α-helix	trans	-69.4	-56.1	179.3	-65.6	179.5	0	0	0	111.8	V117 V451 N452 I453 V457 S458 F459	V117-L455 HydrophobicContact CG1-CB 4.02Å; V117-L455 HydrophobicContact CG1-CD2 4.16Å; V117-L455 HydrophobicContact CG2-CD2 4.33Å; V451-L455 HydrophobicContact CB-CD1 4.39Å; N452-L455 WeakPolarHBondContact O-CB 3.36Å; N452-L455 PolarHBondContact O-N 3.33Å; I453-L455 PolarHBondContact O-N 3.44Å; L455-V457 VanDerWaalsContact C-N 3.3Å; L455-V457 PolarHBondContact O-N 3.46Å; L455-S458 PolarHBondContact O-N 2.72Å; L455-S458 PolarHBondContact O-OG 3.25Å; L455-F459 WeakPolarHBondContact O-CB 3.49Å; L455-F459 PolarHBondContact O-N 3.02Å
456	P	93.3	Very high	90.4	Very high	0 Å²	0	60 Å²	60	0%	0	31%	0.313	C	S	.	.	H	α-helix	trans	-55.2	-41	172.5	-27.9	33	0	0	0	114.1	I432 M435 M436 V451 N452 I453 F459 V460	I432-P456 HydrophobicContact CG2-CB 3.86Å; M435-P456 HydrophobicContact CE-CG 4.06Å; M435-P456 HydrophobicContact SD-CG 4.16Å; M436-P456 HydrophobicContact CG-CB 3.83Å; M436-P456 HydrophobicContact SD-CB 3.78Å; V451-P456 HydrophobicContact CG2-CG 3.93Å; N452-P456 WeakPolarHBondContact O-CD 3.31Å; I453-P456 WeakPolarHBondContact O-CD 3.5Å; P456-F459 PolarHBondContact O-N 3.28Å; P456-V460 WeakPolarHBondContact O-CB 3.43Å; P456-V460 WeakPolarHBondContact O-CG2 3.39Å; P456-V460 PolarHBondContact O-N 3.34Å
457	V	94	Very high	90.6	Very high	60 Å²	60	52.5 Å²	52.5	36%	0.364	28%	0.278	S	S	.	.	H	α-helix	trans	-66	-50	-178.8	172.4	0	0	0	0	111	M436 I453 L455 F459 V460 L461	M436-V457 HydrophobicContact SD-CG2 3.76Å; I453-V457 HydrophobicContact CG1-CG2 4.24Å; I453-V457 VanDerWaalsContact O-CG2 3.3Å; I453-V457 WeakPolarHBondContact O-CG2 3.27Å; I453-V457 PolarHBondContact O-N 3.37Å; I453-V457 VanDerWaalsContact O-N 3.17Å; L455-V457 VanDerWaalsContact C-N 3.3Å; L455-V457 PolarHBondContact O-N 3.46Å; V457-F459 VanDerWaalsContact C-N 3.27Å; V457-F459 PolarHBondContact O-N 3.37Å; V457-V460 PolarHBondContact O-N 3.11Å; V457-L461 HydrophobicContact CG1-CD1 4.04Å; V457-L461 HydrophobicContact CG1-CG 4.47Å; V457-L461 VanDerWaalsContact O-CG 3.3Å; V457-L461 WeakPolarHBondContact O-CG 3.33Å; V457-L461 PolarHBondContact O-N 3.37Å
458	S	93.3	Very high	90.8	Very high	58 Å²	58	55.2 Å²	55.2	41%	0.406	30%	0.295	S	S	.	.	H	α-helix	trans	-60.5	-38.9	177.4	56.5	0	0	0	0	112	L454 L455 L461 A462	L454-S458 VanDerWaalsContact O-CB 3.29Å; L454-S458 WeakPolarHBondContact O-CB 3.43Å; L454-S458 PolarHBondContact O-N 3.14Å; L454-S458 PolarHBondContact O-OG 3.11Å; L455-S458 PolarHBondContact O-N 2.72Å; L455-S458 PolarHBondContact O-OG 3.25Å; S458-L461 PolarHBondContact O-N 3.4Å; S458-A462 PolarHBondContact O-N 2.97Å
459	F	93.1	Very high	90.8	Very high	2 Å²	2	53 Å²	53	1%	0.009	28%	0.281	C	S	.	.	H	α-helix	trans	-66	-46.1	177.4	-170.2	-95.3	0	0	0	112.6	F114 V117 W277 W425 I428 I432 L455 P456 V457 L461 A462 C463	F114-F459 AromaticContact CD1-CE2 3.85Å; F114-F459 HydrophobicContact CD1-CE2 3.85Å; F114-F459 AromaticContact CD2-CD2 3.82Å; F114-F459 HydrophobicContact CD2-CD2 3.82Å; F114-F459 AromaticContact CD2-CE2 3.96Å; F114-F459 HydrophobicContact CD2-CE2 3.96Å; F114-F459 HydrophobicContact CE1-CD2 4.28Å; F114-F459 AromaticContact CE1-CE2 3.53Å; F114-F459 HydrophobicContact CE1-CE2 3.53Å; F114-F459 AromaticContact CE1-CZ 3.97Å; F114-F459 HydrophobicContact CE1-CZ 3.97Å; F114-F459 AromaticContact CE2-CD2 3.41Å; F114-F459 HydrophobicContact CE2-CD2 3.41Å; F114-F459 VanDerWaalsContact CE2-CD2 3.41Å; F114-F459 AromaticContact CE2-CE2 3.53Å; F114-F459 HydrophobicContact CE2-CE2 3.53Å; F114-F459 HydrophobicContact CE2-CG 4.14Å; F114-F459 HydrophobicContact CE2-CZ 4.37Å; F114-F459 HydrophobicContact CG-CD2 4.37Å; F114-F459 HydrophobicContact CG-CE2 4.11Å; F114-F459 AromaticContact CZ-CD2 3.71Å; F114-F459 HydrophobicContact CZ-CD2 3.71Å; F114-F459 HydrophobicContact CZ-CE1 4.44Å; F114-F459 AromaticContact CZ-CE2 3.35Å; F114-F459 HydrophobicContact CZ-CE2 3.35Å; F114-F459 HydrophobicContact CZ-CG 4.41Å; F114-F459 AromaticContact CZ-CZ 3.81Å; F114-F459 HydrophobicContact CZ-CZ 3.81Å; F114-F459 VanDerWaalsContact O-CE2 3.27Å; F114-F459 WeakPolarHBondContact O-CE2 3.28Å; V117-F459 HydrophobicContact CB-CD2 4.25Å; V117-F459 HydrophobicContact CG1-CB 3.98Å; V117-F459 HydrophobicContact CG1-CD2 4.17Å; V117-F459 HydrophobicContact CG1-CG 4.46Å; W277-F459 HydrophobicContact CH2-CZ 4.3Å; W277-F459 HydrophobicContact CZ2-CZ 4.23Å; W425-F459 HydrophobicContact CZ3-CE1 4.46Å; W425-F459 HydrophobicContact CZ3-CE2 4.5Å; W425-F459 AromaticContact CZ3-CZ 3.78Å; W425-F459 HydrophobicContact CZ3-CZ 3.78Å; I428-F459 HydrophobicContact CG2-CE1 3.56Å; I428-F459 HydrophobicContact CG2-CZ 4.02Å; I432-F459 HydrophobicContact CD1-CD1 3.18Å; I432-F459 HydrophobicContact CD1-CE1 3.17Å; I432-F459 HydrophobicContact CD1-CG 4.27Å; I432-F459 HydrophobicContact CD1-CZ 4.26Å; L455-F459 WeakPolarHBondContact O-CB 3.49Å; L455-F459 PolarHBondContact O-N 3.02Å; P456-F459 PolarHBondContact O-N 3.28Å; V457-F459 VanDerWaalsContact C-N 3.27Å; V457-F459 PolarHBondContact O-N 3.37Å; F459-L461 VanDerWaalsContact C-N 3.34Å; F459-L461 PolarHBondContact O-N 3.18Å; F459-A462 PolarHBondContact O-N 3.02Å; F459-C463 WeakPolarHBondContact CE1-SG 3.25Å; F459-C463 PolarHBondContact O-N 2.87Å; F459-C463 PolarHBondContact O-SG 3.32Å; F459-C463 VanDerWaalsContact O-SG 3.34Å
460	V	94.2	Very high	90.6	Very high	13 Å²	13	51.9 Å²	51.9	8%	0.079	28%	0.275	C	S	.	.	H	α-helix	trans	-63.2	-40.9	176.6	168.8	0	0	0	0	111.3	I432 V433 M436 P456 V457 A462 C463 L464	I432-V460 HydrophobicContact CB-CG2 4.01Å; I432-V460 HydrophobicContact CG2-CG2 3.64Å; V433-V460 HydrophobicContact CG2-CG1 3.81Å; V433-V460 HydrophobicContact CG2-CG2 4.01Å; M436-V460 HydrophobicContact CE-CB 4.27Å; M436-V460 HydrophobicContact CE-CG2 3.73Å; P456-V460 WeakPolarHBondContact O-CB 3.43Å; P456-V460 WeakPolarHBondContact O-CG2 3.39Å; P456-V460 PolarHBondContact O-N 3.34Å; V457-V460 PolarHBondContact O-N 3.11Å; V460-A462 VanDerWaalsContact C-N 3.31Å; V460-A462 PolarHBondContact O-N 3.22Å; V460-C463 PolarHBondContact O-N 3.47Å; V460-L464 HydrophobicContact CG1-CD1 3.98Å; V460-L464 HydrophobicContact CG1-CG 4.26Å; V460-L464 WeakPolarHBondContact O-CB 2.99Å; V460-L464 VanDerWaalsContact O-CG 3.28Å; V460-L464 WeakPolarHBondContact O-CG 3.49Å; V460-L464 PolarHBondContact O-N 3.33Å
461	L	93.4	Very high	90.5	Very high	109 Å²	109	48.5 Å²	48.5	57%	0.571	26%	0.26	S	S	*	.	H	α-helix	trans	-60	-42.2	175.5	-72.4	173.2	0	0	0	111.9	V457 S458 F459 L464 F465	V457-L461 HydrophobicContact CG1-CD1 4.04Å; V457-L461 HydrophobicContact CG1-CG 4.47Å; V457-L461 VanDerWaalsContact O-CG 3.3Å; V457-L461 WeakPolarHBondContact O-CG 3.33Å; V457-L461 PolarHBondContact O-N 3.37Å; S458-L461 PolarHBondContact O-N 3.4Å; F459-L461 VanDerWaalsContact C-N 3.34Å; F459-L461 PolarHBondContact O-N 3.18Å; L461-L464 PolarHBondContact O-N 2.93Å; L461-F465 WeakPolarHBondContact O-CB 3.44Å; L461-F465 PolarHBondContact O-N 3.49Å
462	A	90.9	Very high	90.2	Very high	32 Å²	32	58.3 Å²	58.3	26%	0.264	30%	0.296	S	S	.	.	H	α-helix	trans	-70.2	-37.3	176.1	0	0	0	0	0	112.7	F114 S458 F459 V460 L464 F465 L466	F114-A462 HydrophobicContact CD2-CB 3.99Å; F114-A462 HydrophobicContact CE2-CB 3.38Å; F114-A462 HydrophobicContact CZ-CB 4.26Å; S458-A462 PolarHBondContact O-N 2.97Å; F459-A462 PolarHBondContact O-N 3.02Å; V460-A462 VanDerWaalsContact C-N 3.31Å; V460-A462 PolarHBondContact O-N 3.22Å; A462-L464 PolarHBondContact O-N 2.65Å; A462-F465 WeakPolarHBondContact O-CB 3.31Å; A462-F465 PolarHBondContact O-N 3.15Å; A462-L466 WeakPolarHBondContact O-CG 3.45Å; A462-L466 PolarHBondContact O-N 2.86Å
463	C	92.2	Very high	89.7	Confident	0 Å²	0	57.6 Å²	57.6	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-60.6	-44.1	170.1	-69.2	0	0	0	0	112	A429 F459 V460 F465 L466 I467	A429-C463 HydrophobicContact CB-CB 3.87Å; F459-C463 WeakPolarHBondContact CE1-SG 3.25Å; F459-C463 PolarHBondContact O-N 2.87Å; F459-C463 PolarHBondContact O-SG 3.32Å; F459-C463 VanDerWaalsContact O-SG 3.34Å; V460-C463 PolarHBondContact O-N 3.47Å; C463-F465 VanDerWaalsContact C-N 3.34Å; C463-L466 PolarHBondContact O-N 3.37Å; C463-I467 WeakPolarHBondContact O-CD1 3.37Å; C463-I467 VanDerWaalsContact O-CG1 3.23Å; C463-I467 WeakPolarHBondContact O-CG1 3.34Å; C463-I467 PolarHBondContact O-N 3.42Å
464	L	91.6	Very high	89.2	Confident	80 Å²	80	55.2 Å²	55.2	42%	0.419	28%	0.276	S	S	.	.	H	α-helix	trans	-63.1	-42.1	177	-72.7	172.9	0	0	0	111.3	V460 L461 A462 L466 I467 I468	V460-L464 HydrophobicContact CG1-CD1 3.98Å; V460-L464 HydrophobicContact CG1-CG 4.26Å; V460-L464 WeakPolarHBondContact O-CB 2.99Å; V460-L464 VanDerWaalsContact O-CG 3.28Å; V460-L464 WeakPolarHBondContact O-CG 3.49Å; V460-L464 PolarHBondContact O-N 3.33Å; L461-L464 PolarHBondContact O-N 2.93Å; A462-L464 PolarHBondContact O-N 2.65Å; L464-L466 PolarHBondContact O-N 3.29Å; L464-I467 PolarHBondContact O-N 3.26Å; L464-I468 WeakPolarHBondContact O-CB 3.5Å; L464-I468 WeakPolarHBondContact O-CD1 3.46Å; L464-I468 VanDerWaalsContact O-CG1 3.23Å; L464-I468 WeakPolarHBondContact O-CG1 3.31Å; L464-I468 PolarHBondContact O-N 3.5Å
465	F	89	Confident	89	Confident	78 Å²	78	53 Å²	53	34%	0.342	27%	0.269	S	S	.	.	H	α-helix	trans	-55.8	-49.9	174	169.5	-100.6	0	0	0	111.4	L461 A462 C463 I467 I468 V469	L461-F465 WeakPolarHBondContact O-CB 3.44Å; L461-F465 PolarHBondContact O-N 3.49Å; A462-F465 WeakPolarHBondContact O-CB 3.31Å; A462-F465 PolarHBondContact O-N 3.15Å; C463-F465 VanDerWaalsContact C-N 3.34Å; F465-I467 PolarHBondContact O-N 3.22Å; F465-I468 PolarHBondContact O-N 3.39Å; F465-V469 HydrophobicContact CD2-CG2 4.33Å; F465-V469 HydrophobicContact CE1-CG2 4.24Å; F465-V469 HydrophobicContact CE2-CG2 3.87Å; F465-V469 HydrophobicContact CZ-CG2 3.82Å; F465-V469 WeakPolarHBondContact O-CG2 3.3Å; F465-V469 PolarHBondContact O-N 3.49Å
466	L	87.5	Confident	88.8	Confident	4 Å²	4	58.5 Å²	58.5	2%	0.021	29%	0.291	C	S	.	.	H	α-helix	trans	-56.8	-52.2	176.8	-70.2	174.4	0	0	0	110.9	F114 L267 Y268 L271 W425 A462 C463 L464 I468 V469 S470	F114-L466 HydrophobicContact CZ-CD1 4.47Å; L267-L466 HydrophobicContact CB-CD2 3.88Å; L267-L466 HydrophobicContact CD1-CD2 4.14Å; Y268-L466 HydrophobicContact CD1-CD2 4.28Å; Y268-L466 HydrophobicContact CE1-CB 3.65Å; Y268-L466 HydrophobicContact CE1-CD1 4.11Å; Y268-L466 HydrophobicContact CE1-CD2 4.01Å; Y268-L466 HydrophobicContact CE1-CG 4.13Å; Y268-L466 PolarHBondContact OH-O 3.27Å; L271-L466 HydrophobicContact CD1-CD1 3.55Å; W425-L466 HydrophobicContact CD2-CD1 4.38Å; W425-L466 HydrophobicContact CG-CD1 4.45Å; A462-L466 WeakPolarHBondContact O-CG 3.45Å; A462-L466 PolarHBondContact O-N 2.86Å; C463-L466 PolarHBondContact O-N 3.37Å; L464-L466 PolarHBondContact O-N 3.29Å; L466-I468 VanDerWaalsContact C-N 3.31Å; L466-I468 PolarHBondContact O-N 2.86Å; L466-V469 PolarHBondContact O-N 2.9Å; L466-V469 VanDerWaalsContact O-N 3.14Å; L466-S470 PolarHBondContact O-N 3.45Å
467	I	88.9	Confident	88.4	Confident	13 Å²	13	60.2 Å²	60.2	7%	0.067	30%	0.298	C	S	.	.	H	α-helix	trans	-55.7	-44.5	180	-69.4	164.7	0	0	0	111.4	Y268 F422 L426 C463 L464 F465 S470 F471	Y268-I467 PolarHBondContact OH-N 3.46Å; F422-I467 HydrophobicContact CD2-CG2 4.5Å; F422-I467 HydrophobicContact CE2-CB 4.34Å; F422-I467 HydrophobicContact CE2-CG2 3.66Å; F422-I467 HydrophobicContact CZ-CG2 4.11Å; L426-I467 HydrophobicContact CB-CD1 4.34Å; L426-I467 HydrophobicContact CD1-CD1 4.15Å; C463-I467 WeakPolarHBondContact O-CD1 3.37Å; C463-I467 VanDerWaalsContact O-CG1 3.23Å; C463-I467 WeakPolarHBondContact O-CG1 3.34Å; C463-I467 PolarHBondContact O-N 3.42Å; L464-I467 PolarHBondContact O-N 3.26Å; F465-I467 PolarHBondContact O-N 3.22Å; I467-S470 WeakPolarHBondContact O-CB 3.45Å; I467-S470 PolarHBondContact O-N 2.92Å; I467-F471 HydrophobicContact CG2-CD2 4.06Å; I467-F471 HydrophobicContact CG2-CE2 3.79Å; I467-F471 WeakPolarHBondContact O-CD2 3.49Å; I467-F471 PolarHBondContact O-N 3.25Å
468	I	88.8	Confident	88	Confident	100 Å²	100	57.5 Å²	57.5	51%	0.513	28%	0.282	S	S	.	.	H	α-helix	trans	-63.9	-43.7	179.1	-68.8	164.1	0	0	0	111	L464 F465 L466 S470 F471 W472	L464-I468 WeakPolarHBondContact O-CB 3.5Å; L464-I468 WeakPolarHBondContact O-CD1 3.46Å; L464-I468 VanDerWaalsContact O-CG1 3.23Å; L464-I468 WeakPolarHBondContact O-CG1 3.31Å; L464-I468 PolarHBondContact O-N 3.5Å; F465-I468 PolarHBondContact O-N 3.39Å; L466-I468 VanDerWaalsContact C-N 3.31Å; L466-I468 PolarHBondContact O-N 2.86Å; I468-S470 VanDerWaalsContact C-N 3.31Å; I468-S470 PolarHBondContact O-N 3.36Å; I468-F471 PolarHBondContact O-N 2.93Å; I468-W472 PolarHBondContact O-N 3.32Å
469	V	85.2	Confident	87.9	Confident	13 Å²	13	57.8 Å²	57.8	8%	0.079	29%	0.288	C	S	.	.	H	α-helix	trans	-62	-40.2	177.5	171.4	0	0	0	0	111.3	F465 L466 F471 W472 K473	F465-V469 HydrophobicContact CD2-CG2 4.33Å; F465-V469 HydrophobicContact CE1-CG2 4.24Å; F465-V469 HydrophobicContact CE2-CG2 3.87Å; F465-V469 HydrophobicContact CZ-CG2 3.82Å; F465-V469 WeakPolarHBondContact O-CG2 3.3Å; F465-V469 PolarHBondContact O-N 3.49Å; L466-V469 PolarHBondContact O-N 2.9Å; L466-V469 VanDerWaalsContact O-N 3.14Å; V469-F471 PolarHBondContact O-N 3.45Å; V469-W472 PolarHBondContact O-N 2.88Å; V469-W472 VanDerWaalsContact O-N 3.16Å; V469-K473 HydrophobicContact CG1-CG 4.31Å; V469-K473 PolarHBondContact O-N 3.43Å
470	S	81.9	Confident	87.7	Confident	0 Å²	0	63 Å²	63	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-57.7	-46	174.3	-81	0	0	0	0	112.8	Y268 F422 L466 I467 I468 W472 K473 T474	Y268-S470 WeakPolarHBondContact CE2-OG 3.19Å; Y268-S470 PolarHBondContact OH-OG 3.4Å; F422-S470 VanDerWaalsContact CD2-CB 3.45Å; L466-S470 PolarHBondContact O-N 3.45Å; I467-S470 WeakPolarHBondContact O-CB 3.45Å; I467-S470 PolarHBondContact O-N 2.92Å; I468-S470 VanDerWaalsContact C-N 3.31Å; I468-S470 PolarHBondContact O-N 3.36Å; S470-W472 PolarHBondContact O-N 2.87Å; S470-K473 PolarHBondContact O-N 3.36Å; S470-T474 CarbonylContact O-C 3.57Å; S470-T474 PolarHBondContact O-N 2.95Å; S470-T474 PolarHBondContact O-OG1 3.35Å
471	F	84.9	Confident	87.4	Confident	88 Å²	88	62.4 Å²	62.4	39%	0.386	31%	0.311	S	S	.	.	H	α-helix	trans	-59.1	-33.7	178.8	-85	-72.2	0	0	0	112.6	F422 I467 I468 V469 P475 C478 F482	F422-F471 AromaticContact CE2-CD2 3.91Å; F422-F471 HydrophobicContact CE2-CD2 3.91Å; F422-F471 AromaticContact CE2-CE2 3.71Å; F422-F471 HydrophobicContact CE2-CE2 3.71Å; F422-F471 HydrophobicContact CE2-CZ 4.22Å; F422-F471 HydrophobicContact CZ-CD2 4.23Å; F422-F471 HydrophobicContact CZ-CE1 4.36Å; F422-F471 AromaticContact CZ-CE2 3.59Å; F422-F471 HydrophobicContact CZ-CE2 3.59Å; F422-F471 AromaticContact CZ-CZ 3.71Å; F422-F471 HydrophobicContact CZ-CZ 3.71Å; I467-F471 HydrophobicContact CG2-CD2 4.06Å; I467-F471 HydrophobicContact CG2-CE2 3.79Å; I467-F471 WeakPolarHBondContact O-CD2 3.49Å; I467-F471 PolarHBondContact O-N 3.25Å; I468-F471 PolarHBondContact O-N 2.93Å; V469-F471 PolarHBondContact O-N 3.45Å; F471-P475 WeakPolarHBondContact O-CB 3.39Å; F471-C478 HydrophobicContact CD1-CB 4.01Å; F471-C478 HydrophobicContact CE1-CB 4.1Å; F471-F482 HydrophobicContact CE1-CD2 4.14Å; F471-F482 AromaticContact CE1-CE2 3.45Å; F471-F482 HydrophobicContact CE1-CE2 3.45Å; F471-F482 VanDerWaalsContact CE1-CE2 3.45Å; F471-F482 HydrophobicContact CE1-CZ 4.28Å; F471-F482 HydrophobicContact CE2-CE2 4.26Å; F471-F482 HydrophobicContact CE2-CZ 4.42Å; F471-F482 HydrophobicContact CZ-CD2 4.23Å; F471-F482 AromaticContact CZ-CE2 3.18Å; F471-F482 HydrophobicContact CZ-CE2 3.18Å; F471-F482 AromaticContact CZ-CZ 3.56Å; F471-F482 HydrophobicContact CZ-CZ 3.56Å
472	W	84.9	Confident	87.3	Confident	225 Å²	225	60.9 Å²	60.9	85%	0.852	30%	0.3	S	S	*	.	H	α-helix	trans	-78	-43.5	178.6	-84.8	42.6	0	0	0	112.8	I468 V469 S470	I468-W472 PolarHBondContact O-N 3.32Å; V469-W472 PolarHBondContact O-N 2.88Å; V469-W472 VanDerWaalsContact O-N 3.16Å; S470-W472 PolarHBondContact O-N 2.87Å
473	K	81.2	Confident	87.4	Confident	86 Å²	86	61.2 Å²	61.2	37%	0.374	31%	0.306	S	S	.	.	H	α-helix	trans	-83.8	-38.2	-174.4	-75.7	-76.5	-174.6	165.2	0	113	G261 N262 L265 V469 S470 P475	G261-K473 VanDerWaalsContact CA-CE 3.5Å; N262-K473 PolarHBondContact OD1-NZ 2.88Å; L265-K473 HydrophobicContact CD1-CB 4.32Å; L265-K473 HydrophobicContact CD1-CD 4.16Å; L265-K473 HydrophobicContact CD1-CG 4.18Å; L265-K473 HydrophobicContact CD2-CB 4.4Å; L265-K473 HydrophobicContact CG-CG 4.48Å; V469-K473 HydrophobicContact CG1-CG 4.31Å; V469-K473 PolarHBondContact O-N 3.43Å; S470-K473 PolarHBondContact O-N 3.36Å; K473-P475 VanDerWaalsContact C-CD 3.48Å
474	T	81.1	Confident	87.3	Confident	22 Å²	22	63.3 Å²	63.3	14%	0.135	32%	0.317	C	S	.	.			trans	-131.4	57.7	-176.3	61.2	0	0	0	0	113.8	S470 K476 E477 C478	S470-T474 CarbonylContact O-C 3.57Å; S470-T474 PolarHBondContact O-N 2.95Å; S470-T474 PolarHBondContact O-OG1 3.35Å; T474-K476 VanDerWaalsContact C-N 3.26Å; T474-K476 PolarHBondContact O-N 3.24Å; T474-K476 VanDerWaalsContact O-N 3.12Å; T474-E477 WeakPolarHBondContact CB-OE2 3.47Å; T474-E477 WeakPolarHBondContact CG2-OE2 3.36Å; T474-E477 PolarHBondContact O-N 3.4Å; T474-E477 PolarHBondContact OG1-OE2 2.74Å; T474-C478 PolarHBondContact O-N 2.92Å
475	P	88	Confident	87.4	Confident	72 Å²	72	60.6 Å²	60.6	47%	0.468	30%	0.303	S	S	.	.	H	α-helix	trans	-59.8	-31.9	-174.1	22.8	-34	0	0	0	114.1	F471 K473 A479	F471-P475 WeakPolarHBondContact O-CB 3.39Å; K473-P475 VanDerWaalsContact C-CD 3.48Å; P475-A479 VanDerWaalsContact O-CB 3.28Å; P475-A479 WeakPolarHBondContact O-CB 3.22Å; P475-A479 PolarHBondContact O-N 2.96Å
476	K	87.4	Confident	87.6	Confident	174 Å²	174	59.4 Å²	59.4	76%	0.757	31%	0.307	S	S	*	.	H	α-helix	trans	-64.9	-44.9	-179.9	-67.2	-178.8	-179.8	176.5	0	111.8	T474 A479 I480	T474-K476 VanDerWaalsContact C-N 3.26Å; T474-K476 PolarHBondContact O-N 3.24Å; T474-K476 VanDerWaalsContact O-N 3.12Å; K476-A479 PolarHBondContact O-N 2.91Å; K476-I480 VanDerWaalsContact O-CG1 3.31Å; K476-I480 WeakPolarHBondContact O-CG1 3.4Å; K476-I480 PolarHBondContact O-N 3.3Å
477	E	85.1	Confident	88	Confident	35 Å²	35	62.5 Å²	62.5	16%	0.164	33%	0.326	C	S	.	.	H	α-helix	trans	-66.1	-45.8	-179.8	-67.1	162.5	-173.6	0	0	110.5	S415 F419 T474 A479 I480 G481	S415-E477 WeakPolarHBondContact CB-OE1 3.49Å; S415-E477 VanDerWaalsContact OG-CD 3.26Å; S415-E477 PolarHBondContact OG-OE1 2.79Å; F419-E477 HydrophobicContact CD2-CB 4.24Å; F419-E477 WeakPolarHBondContact CD2-O 3.29Å; F419-E477 WeakPolarHBondContact CE2-O 3.41Å; T474-E477 WeakPolarHBondContact CB-OE2 3.47Å; T474-E477 WeakPolarHBondContact CG2-OE2 3.36Å; T474-E477 PolarHBondContact O-N 3.4Å; T474-E477 PolarHBondContact OG1-OE2 2.74Å; E477-A479 VanDerWaalsContact C-N 3.35Å; E477-A479 PolarHBondContact O-N 3.05Å; E477-I480 PolarHBondContact O-N 2.89Å; E477-G481 PolarHBondContact O-N 3.49Å; E477-G481 VanDerWaalsContact O-N 3.1Å
478	C	86.3	Confident	88.1	Confident	3 Å²	3	61.9 Å²	61.9	2%	0.02	32%	0.323	C	S	.	.	H	α-helix	trans	-57.7	-47.2	174.1	-64.2	0	0	0	0	111.3	F422 F471 T474 I480 G481 F482	F422-C478 HydrophobicContact CZ-CB 4.48Å; F471-C478 HydrophobicContact CD1-CB 4.01Å; F471-C478 HydrophobicContact CE1-CB 4.1Å; T474-C478 PolarHBondContact O-N 2.92Å; C478-I480 PolarHBondContact O-N 3.46Å; C478-G481 PolarHBondContact O-N 2.9Å; C478-F482 WeakPolarHBondContact O-CD2 3.48Å; C478-F482 PolarHBondContact O-N 3.06Å
479	A	89.3	Confident	88.3	Confident	65 Å²	65	60.2 Å²	60.2	54%	0.537	32%	0.315	S	S	.	.	H	α-helix	trans	-60.9	-44	-179.3	0	0	0	0	0	112.6	P475 K476 E477 G481 F482 G483	P475-A479 VanDerWaalsContact O-CB 3.28Å; P475-A479 WeakPolarHBondContact O-CB 3.22Å; P475-A479 PolarHBondContact O-N 2.96Å; K476-A479 PolarHBondContact O-N 2.91Å; E477-A479 VanDerWaalsContact C-N 3.35Å; E477-A479 PolarHBondContact O-N 3.05Å; A479-G481 VanDerWaalsContact C-N 3.31Å; A479-G481 PolarHBondContact O-N 2.88Å; A479-F482 PolarHBondContact O-N 3.11Å; A479-G483 PolarHBondContact O-N 2.77Å
480	I	89.7	Confident	88.7	Confident	111 Å²	111	63 Å²	63	57%	0.569	33%	0.334	S	S	*	.	H	α-helix	trans	-59.1	-45.6	175.8	-68.8	164.6	0	0	0	110.3	K476 E477 C478 G483 I484	K476-I480 VanDerWaalsContact O-CG1 3.31Å; K476-I480 WeakPolarHBondContact O-CG1 3.4Å; K476-I480 PolarHBondContact O-N 3.3Å; E477-I480 PolarHBondContact O-N 2.89Å; C478-I480 PolarHBondContact O-N 3.46Å; I480-G483 WeakPolarHBondContact O-CA 3.18Å; I480-G483 PolarHBondContact O-N 3.12Å; I480-G483 VanDerWaalsContact O-N 3.1Å; I480-I484 HydrophobicContact CG2-CD1 4.24Å; I480-I484 PolarHBondContact O-N 3.09Å
481	G	87.8	Confident	89.2	Confident	0 Å²	0	66 Å²	66	0%	0	35%	0.352	C	S	.	.	H	α-helix	trans	-71.3	-34.5	-177.3	0	0	0	0	0	113.8	E477 C478 A479 G483 I484 I485	E477-G481 PolarHBondContact O-N 3.49Å; E477-G481 VanDerWaalsContact O-N 3.1Å; C478-G481 PolarHBondContact O-N 2.9Å; A479-G481 VanDerWaalsContact C-N 3.31Å; A479-G481 PolarHBondContact O-N 2.88Å; G481-G483 VanDerWaalsContact C-N 3.26Å; G481-G483 PolarHBondContact O-N 3.36Å; G481-I484 PolarHBondContact O-N 3.33Å; G481-I485 WeakPolarHBondContact O-CG1 3.07Å; G481-I485 PolarHBondContact O-N 3.33Å
482	F	91.1	Very high	89.5	Confident	78 Å²	78	62.8 Å²	62.8	34%	0.342	34%	0.337	S	S	.	.	H	α-helix	trans	-63.5	-34.7	167.2	-78.7	-67.8	0	0	0	112.1	F422 F471 C478 A479 I485 A486	F422-F482 AromaticContact CE1-CE2 3.58Å; F422-F482 HydrophobicContact CE1-CE2 3.58Å; F422-F482 AromaticContact CE1-CZ 3.69Å; F422-F482 HydrophobicContact CE1-CZ 3.69Å; F422-F482 AromaticContact CZ-CE2 3.52Å; F422-F482 HydrophobicContact CZ-CE2 3.52Å; F422-F482 AromaticContact CZ-CZ 3.66Å; F422-F482 HydrophobicContact CZ-CZ 3.66Å; F471-F482 HydrophobicContact CE1-CD2 4.14Å; F471-F482 AromaticContact CE1-CE2 3.45Å; F471-F482 HydrophobicContact CE1-CE2 3.45Å; F471-F482 VanDerWaalsContact CE1-CE2 3.45Å; F471-F482 HydrophobicContact CE1-CZ 4.28Å; F471-F482 HydrophobicContact CE2-CE2 4.26Å; F471-F482 HydrophobicContact CE2-CZ 4.42Å; F471-F482 HydrophobicContact CZ-CD2 4.23Å; F471-F482 AromaticContact CZ-CE2 3.18Å; F471-F482 HydrophobicContact CZ-CE2 3.18Å; F471-F482 AromaticContact CZ-CZ 3.56Å; F471-F482 HydrophobicContact CZ-CZ 3.56Å; C478-F482 WeakPolarHBondContact O-CD2 3.48Å; C478-F482 PolarHBondContact O-N 3.06Å; A479-F482 PolarHBondContact O-N 3.11Å; F482-I485 HydrophobicContact CD1-CD1 4.3Å; F482-I485 PolarHBondContact O-N 2.84Å; F482-A486 WeakPolarHBondContact O-CB 3.42Å; F482-A486 PolarHBondContact O-N 3.39Å
483	G	92.7	Very high	89.7	Confident	38 Å²	38	57.3 Å²	57.3	39%	0.392	32%	0.32	S	S	.	.	H	α-helix	trans	-56	-48.5	169.5	0	0	0	0	0	111.9	A479 I480 G481 I485 A486 T487	A479-G483 PolarHBondContact O-N 2.77Å; I480-G483 WeakPolarHBondContact O-CA 3.18Å; I480-G483 PolarHBondContact O-N 3.12Å; I480-G483 VanDerWaalsContact O-N 3.1Å; G481-G483 VanDerWaalsContact C-N 3.26Å; G481-G483 PolarHBondContact O-N 3.36Å; G483-I485 VanDerWaalsContact C-N 3.35Å; G483-I485 PolarHBondContact O-N 3.15Å; G483-A486 WeakPolarHBondContact O-CB 3.41Å; G483-A486 PolarHBondContact O-N 3.06Å; G483-A486 VanDerWaalsContact O-N 3.16Å; G483-T487 WeakPolarHBondContact O-CG2 3.38Å; G483-T487 PolarHBondContact O-N 3.42Å
484	I	91.4	Very high	90	Very high	45 Å²	45	56.5 Å²	56.5	23%	0.231	32%	0.322	C	S	.	.	H	α-helix	trans	-64.3	-37	177.5	-65.1	167.7	0	0	0	111.9	W153 L157 I158 F419 I480 G481 T487 G488	W153-I484 PolarHBondContact NE1-O 2.54Å; W153-I484 VanDerWaalsContact NE1-O 3.11Å; L157-I484 HydrophobicContact CB-CG2 4.24Å; L157-I484 HydrophobicContact CD1-CG2 3.96Å; I158-I484 HydrophobicContact CD1-CB 4.27Å; I158-I484 HydrophobicContact CD1-CG2 4.03Å; I158-I484 HydrophobicContact CG1-CD1 4.49Å; I158-I484 HydrophobicContact CG1-CG2 4.21Å; F419-I484 HydrophobicContact CZ-CD1 4.08Å; I480-I484 HydrophobicContact CG2-CD1 4.24Å; I480-I484 PolarHBondContact O-N 3.09Å; G481-I484 PolarHBondContact O-N 3.33Å; I484-T487 PolarHBondContact O-N 3.03Å; I484-T487 PolarHBondContact O-OG1 3.12Å; I484-G488 PolarHBondContact O-N 2.94Å
485	I	92.9	Very high	90.2	Very high	23 Å²	23	57.1 Å²	57.1	12%	0.118	33%	0.332	C	S	.	.	H	α-helix	trans	-65	-43.7	173	-66.2	174.6	0	0	0	110.5	L150 I154 F423 L426 G481 F482 G483 T487 G488	L150-I485 HydrophobicContact CD2-CG2 4.26Å; I154-I485 HydrophobicContact CD1-CD1 3.51Å; I154-I485 HydrophobicContact CD1-CG1 3.73Å; I154-I485 HydrophobicContact CG1-CD1 3.84Å; I154-I485 HydrophobicContact CG1-CG1 3.54Å; F423-I485 HydrophobicContact CD1-CD1 3.66Å; F423-I485 HydrophobicContact CE1-CD1 3.35Å; F423-I485 HydrophobicContact CE1-CG1 4.25Å; F423-I485 HydrophobicContact CZ-CD1 4.46Å; L426-I485 HydrophobicContact CD2-CD1 4.49Å; G481-I485 WeakPolarHBondContact O-CG1 3.07Å; G481-I485 PolarHBondContact O-N 3.33Å; F482-I485 HydrophobicContact CD1-CD1 4.3Å; F482-I485 PolarHBondContact O-N 2.84Å; G483-I485 VanDerWaalsContact C-N 3.35Å; G483-I485 PolarHBondContact O-N 3.15Å; I485-T487 PolarHBondContact O-N 3.42Å; I485-G488 WeakPolarHBondContact O-CA 3.22Å; I485-G488 PolarHBondContact O-N 3.29Å
486	A	93.4	Very high	90	Very high	52 Å²	52	55.4 Å²	55.4	43%	0.43	32%	0.321	S	S	.	.	H	α-helix	trans	-62.4	-32.5	179.5	0	0	0	0	0	111.7	F482 G483 G488 L489 P490	F482-A486 WeakPolarHBondContact O-CB 3.42Å; F482-A486 PolarHBondContact O-N 3.39Å; G483-A486 WeakPolarHBondContact O-CB 3.41Å; G483-A486 PolarHBondContact O-N 3.06Å; G483-A486 VanDerWaalsContact O-N 3.16Å; A486-G488 PolarHBondContact O-N 3.24Å; A486-L489 WeakPolarHBondContact O-CB 3.42Å; A486-L489 PolarHBondContact O-N 3.18Å; A486-P490 WeakPolarHBondContact O-CD 3.3Å
487	T	94.9	Very high	89.9	Confident	69 Å²	69	50 Å²	50	42%	0.423	30%	0.304	S	S	.	.	H	α-helix	trans	-67.2	-20.4	172	71.6	0	0	0	0	113.1	G483 I484 I485 L489 P490 V491	G483-T487 WeakPolarHBondContact O-CG2 3.38Å; G483-T487 PolarHBondContact O-N 3.42Å; I484-T487 PolarHBondContact O-N 3.03Å; I484-T487 PolarHBondContact O-OG1 3.12Å; I485-T487 PolarHBondContact O-N 3.42Å; T487-L489 VanDerWaalsContact C-N 3.33Å; T487-P490 VanDerWaalsContact O-CD 3.28Å; T487-P490 WeakPolarHBondContact O-CD 3.27Å; T487-P490 WeakPolarHBondContact O-CG 3.38Å; T487-V491 VanDerWaalsContact O-CG2 3.28Å; T487-V491 WeakPolarHBondContact O-CG2 3.33Å
488	G	92	Very high	89.9	Confident	0 Å²	0	53.6 Å²	53.6	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-66.7	-31.5	173	0	0	0	0	0	113.1	F149 I484 I485 A486 V491 Y492	F149-G488 VanDerWaalsContact CE1-O 3.27Å; F149-G488 WeakPolarHBondContact CE1-O 3.19Å; I484-G488 PolarHBondContact O-N 2.94Å; I485-G488 WeakPolarHBondContact O-CA 3.22Å; I485-G488 PolarHBondContact O-N 3.29Å; A486-G488 PolarHBondContact O-N 3.24Å; G488-V491 PolarHBondContact O-N 3.47Å; G488-Y492 WeakPolarHBondContact O-CB 3.07Å; G488-Y492 PolarHBondContact O-N 3.22Å
489	L	93.1	Very high	89.4	Confident	66 Å²	66	62.2 Å²	62.2	35%	0.346	35%	0.353	S	S	.	.	H	α-helix	trans	-61	-56.3	179.1	-67.4	171.2	0	0	0	113.4	L146 L150 A486 T487 V491 Y492 F493	L146-L489 HydrophobicContact CD1-CD2 3.98Å; L150-L489 HydrophobicContact CD1-CD2 4.12Å; L150-L489 HydrophobicContact CD2-CD2 4.3Å; L150-L489 HydrophobicContact CD2-CG 4.44Å; A486-L489 WeakPolarHBondContact O-CB 3.42Å; A486-L489 PolarHBondContact O-N 3.18Å; T487-L489 VanDerWaalsContact C-N 3.33Å; L489-V491 VanDerWaalsContact C-N 3.27Å; L489-V491 PolarHBondContact O-N 3.26Å; L489-Y492 WeakPolarHBondContact O-CB 3.4Å; L489-Y492 PolarHBondContact O-N 2.82Å; L489-F493 HydrophobicContact CB-CE2 4.47Å; L489-F493 WeakPolarHBondContact O-CD2 3.5Å; L489-F493 PolarHBondContact O-N 3.24Å
490	P	93.1	Very high	89	Confident	71 Å²	71	66.1 Å²	66.1	46%	0.461	37%	0.365	S	S	.	.	H	α-helix	trans	-62.6	-36.5	178.6	25.1	-33.6	0	0	0	111.6	A486 T487 Y492 F493 V494	A486-P490 WeakPolarHBondContact O-CD 3.3Å; T487-P490 VanDerWaalsContact O-CD 3.28Å; T487-P490 WeakPolarHBondContact O-CD 3.27Å; T487-P490 WeakPolarHBondContact O-CG 3.38Å; P490-Y492 VanDerWaalsContact C-N 3.34Å; P490-Y492 PolarHBondContact O-N 3.1Å; P490-F493 PolarHBondContact O-N 3.33Å; P490-V494 WeakPolarHBondContact O-CB 3.48Å; P490-V494 VanDerWaalsContact O-CG2 3.3Å; P490-V494 WeakPolarHBondContact O-CG2 3.3Å; P490-V494 PolarHBondContact O-N 3.35Å
491	V	92	Very high	88.8	Confident	63 Å²	63	63.6 Å²	63.6	38%	0.382	35%	0.35	S	S	.	.	H	α-helix	trans	-64.3	-39.5	176.4	178.6	0	0	0	0	111.2	F149 W153 T487 G488 L489 G495	F149-V491 HydrophobicContact CZ-CB 4.4Å; F149-V491 HydrophobicContact CZ-CG1 3.96Å; W153-V491 HydrophobicContact CH2-CB 4.23Å; W153-V491 HydrophobicContact CH2-CG1 3.87Å; W153-V491 HydrophobicContact CH2-CG2 3.99Å; W153-V491 HydrophobicContact CZ2-CG2 4.15Å; W153-V491 HydrophobicContact CZ3-CG1 3.86Å; T487-V491 VanDerWaalsContact O-CG2 3.28Å; T487-V491 WeakPolarHBondContact O-CG2 3.33Å; G488-V491 PolarHBondContact O-N 3.47Å; L489-V491 VanDerWaalsContact C-N 3.27Å; L489-V491 PolarHBondContact O-N 3.26Å; V491-G495 VanDerWaalsContact O-CA 3.27Å; V491-G495 WeakPolarHBondContact O-CA 3.34Å; V491-G495 PolarHBondContact O-N 3.3Å
492	Y	90.9	Very high	88.8	Confident	21 Å²	21	65.4 Å²	65.4	8%	0.082	36%	0.362	C	S	.	.	H	α-helix	trans	-64.9	-46.7	175.2	178.8	-103.1	0	0	0	112.2	S145 L146 F149 G488 L489 P490 V494 G495 V496 C497	S145-Y492 VanDerWaalsContact CB-OH 3.32Å; S145-Y492 WeakPolarHBondContact CB-OH 3.28Å; S145-Y492 WeakPolarHBondContact OG-CE2 3.42Å; S145-Y492 PolarHBondContact OG-OH 3.19Å; L146-Y492 HydrophobicContact CB-CE1 3.94Å; L146-Y492 HydrophobicContact CD1-CD1 3.23Å; L146-Y492 HydrophobicContact CD1-CE1 3.47Å; L146-Y492 VanDerWaalsContact CD1-CE1 3.47Å; L146-Y492 HydrophobicContact CD1-CG 3.8Å; L146-Y492 HydrophobicContact CG-CD1 4.47Å; L146-Y492 HydrophobicContact CG-CE1 4.3Å; L146-Y492 PolarHBondContact N-OH 3.03Å; F149-Y492 HydrophobicContact CB-CD2 3.48Å; F149-Y492 VanDerWaalsContact CB-CD2 3.48Å; F149-Y492 HydrophobicContact CB-CE2 3.8Å; F149-Y492 HydrophobicContact CB-CG 4.43Å; F149-Y492 AromaticContact CD1-CD2 3.8Å; F149-Y492 HydrophobicContact CD1-CD2 3.8Å; F149-Y492 HydrophobicContact CD1-CG 4.1Å; F149-Y492 AromaticContact CD2-CD2 3.79Å; F149-Y492 HydrophobicContact CD2-CD2 3.79Å; F149-Y492 AromaticContact CG-CD2 3.39Å; F149-Y492 HydrophobicContact CG-CD2 3.39Å; F149-Y492 HydrophobicContact CG-CE2 4.19Å; F149-Y492 HydrophobicContact CG-CG 4.17Å; G488-Y492 WeakPolarHBondContact O-CB 3.07Å; G488-Y492 PolarHBondContact O-N 3.22Å; L489-Y492 WeakPolarHBondContact O-CB 3.4Å; L489-Y492 PolarHBondContact O-N 2.82Å; P490-Y492 VanDerWaalsContact C-N 3.34Å; P490-Y492 PolarHBondContact O-N 3.1Å; Y492-V494 PolarHBondContact O-N 2.94Å; Y492-G495 PolarHBondContact O-N 3.09Å; Y492-V496 HydrophobicContact CD2-CB 3.88Å; Y492-V496 HydrophobicContact CD2-CG1 4.46Å; Y492-V496 HydrophobicContact CD2-CG2 3.81Å; Y492-V496 HydrophobicContact CE2-CB 3.78Å; Y492-V496 HydrophobicContact CE2-CG1 3.86Å; Y492-V496 HydrophobicContact CE2-CG2 4Å; Y492-V496 WeakPolarHBondContact O-CB 3.29Å; Y492-V496 PolarHBondContact O-N 2.98Å; Y492-C497 WeakPolarHBondContact CE1-SG 3.46Å; Y492-C497 PolarHBondContact O-N 2.85Å
493	F	90.6	Very high	88.6	Confident	110 Å²	110	72.6 Å²	72.6	48%	0.482	39%	0.387	S	S	.	.	I	π-helix	trans	-64.3	-42.3	-179.5	-73.5	-62.8	0	0	0	112	L489 P490 C497 W498	L489-F493 HydrophobicContact CB-CE2 4.47Å; L489-F493 WeakPolarHBondContact O-CD2 3.5Å; L489-F493 PolarHBondContact O-N 3.24Å; P490-F493 PolarHBondContact O-N 3.33Å; F493-C497 HydrophobicContact CD1-CB 4.18Å; F493-W498 WeakPolarHBondContact O-CB 3.31Å; F493-W498 PolarHBondContact O-N 3.47Å
494	V	88.1	Confident	88.5	Confident	69 Å²	69	80 Å²	80	42%	0.418	40%	0.403	S	S	.	.	I	π-helix	trans	-74.1	-38.2	177.5	173.6	0	0	0	0	111.9	P490 Y492 W498 K501	P490-V494 WeakPolarHBondContact O-CB 3.48Å; P490-V494 VanDerWaalsContact O-CG2 3.3Å; P490-V494 WeakPolarHBondContact O-CG2 3.3Å; P490-V494 PolarHBondContact O-N 3.35Å; Y492-V494 PolarHBondContact O-N 2.94Å; V494-W498 HydrophobicContact CG1-CE3 4.2Å; V494-K501 WeakPolarHBondContact O-CE 3.45Å; V494-K501 PolarHBondContact O-NZ 3.43Å
495	G	84.6	Confident	88.3	Confident	35 Å²	35	79.3 Å²	79.3	36%	0.361	40%	0.399	S	S	.	.	I	π-helix	trans	-77.2	-54.3	-174.5	0	0	0	0	0	113	V491 Y492 K501	V491-G495 VanDerWaalsContact O-CA 3.27Å; V491-G495 WeakPolarHBondContact O-CA 3.34Å; V491-G495 PolarHBondContact O-N 3.3Å; Y492-G495 PolarHBondContact O-N 3.09Å; G495-K501 PolarHBondContact O-NZ 2.95Å
496	V	83.7	Confident	87.9	Confident	36 Å²	36	81.7 Å²	81.7	22%	0.218	42%	0.415	C	S	.	.	I	π-helix	trans	-105.8	-49.3	-166.6	-175.2	0	0	0	0	111.8	F149 Y492	F149-V496 HydrophobicContact CD2-CG2 4.36Å; Y492-V496 HydrophobicContact CD2-CB 3.88Å; Y492-V496 HydrophobicContact CD2-CG1 4.46Å; Y492-V496 HydrophobicContact CD2-CG2 3.81Å; Y492-V496 HydrophobicContact CE2-CB 3.78Å; Y492-V496 HydrophobicContact CE2-CG1 3.86Å; Y492-V496 HydrophobicContact CE2-CG2 4Å; Y492-V496 WeakPolarHBondContact O-CB 3.29Å; Y492-V496 PolarHBondContact O-N 2.98Å
497	C	84.6	Confident	87.8	Confident	60 Å²	60	88.3 Å²	88.3	41%	0.405	43%	0.429	S	S	.	.	I	π-helix	trans	-71.8	-35.7	-176.2	-63.6	0	0	0	0	113.1	Y492 F493 K499	Y492-C497 WeakPolarHBondContact CE1-SG 3.46Å; Y492-C497 PolarHBondContact O-N 2.85Å; F493-C497 HydrophobicContact CD1-CB 4.18Å; C497-K499 PolarHBondContact O-N 3.41Å
498	W	85.6	Confident	87.5	Confident	110 Å²	110	86.6 Å²	86.6	42%	0.417	43%	0.425	S	S	.	.			trans	-76.9	88.5	-177.4	-166.3	8.8	0	0	0	111.3	F493 V494 N500 K501 P502 M505	F493-W498 WeakPolarHBondContact O-CB 3.31Å; F493-W498 PolarHBondContact O-N 3.47Å; V494-W498 HydrophobicContact CG1-CE3 4.2Å; W498-N500 PolarHBondContact NE1-O 3.31Å; W498-K501 HydrophobicContact CD2-CG 4.45Å; W498-K501 HydrophobicContact CG-CG 4.35Å; W498-K501 WeakPolarHBondContact O-CE 3.42Å; W498-K501 VanDerWaalsContact O-CG 3.23Å; W498-K501 WeakPolarHBondContact O-CG 3.39Å; W498-P502 HydrophobicContact CH2-CG 3.97Å; W498-P502 VanDerWaalsContact CZ2-CD 3.48Å; W498-P502 HydrophobicContact CZ2-CG 3.87Å; W498-M505 HydrophobicContact CD2-CE 4.48Å; W498-M505 HydrophobicContact CE3-CE 3.84Å; W498-M505 HydrophobicContact CH2-CE 4.42Å; W498-M505 HydrophobicContact CZ3-CE 3.8Å; W498-M505 HydrophobicContact CZ3-SD 4.46Å
499	K	76.6	Confident	87.3	Confident	185 Å²	185	90.5 Å²	90.5	80%	0.804	45%	0.445	S	S	*	.			trans	-73.3	-37.6	177.9	-65.2	-170.2	176.2	-174.2	0	113.1	C497 K501	C497-K499 PolarHBondContact O-N 3.41Å; K499-K501 VanDerWaalsContact C-N 3.31Å; K499-K501 PolarHBondContact O-N 3.38Å; K499-K501 VanDerWaalsContact O-N 3.11Å
500	N	81.1	Confident	87.2	Confident	146 Å²	146	94.4 Å²	94.4	78%	0.781	46%	0.459	S	S	*	.	S	Bend	trans	-90.2	60.4	-177.5	-67.5	-9.5	0	0	0	112.2	W498	W498-N500 PolarHBondContact NE1-O 3.31Å
501	K	85	Confident	87.1	Confident	58 Å²	58	95 Å²	95	25%	0.252	46%	0.462	S	S	.	.			trans	-65.4	139.5	-179.8	-66.5	-177.4	-178.1	-174.6	0	111.1	V494 G495 W498 K499 M505	V494-K501 WeakPolarHBondContact O-CE 3.45Å; V494-K501 PolarHBondContact O-NZ 3.43Å; G495-K501 PolarHBondContact O-NZ 2.95Å; W498-K501 HydrophobicContact CD2-CG 4.45Å; W498-K501 HydrophobicContact CG-CG 4.35Å; W498-K501 WeakPolarHBondContact O-CE 3.42Å; W498-K501 VanDerWaalsContact O-CG 3.23Å; W498-K501 WeakPolarHBondContact O-CG 3.39Å; K499-K501 VanDerWaalsContact C-N 3.31Å; K499-K501 PolarHBondContact O-N 3.38Å; K499-K501 VanDerWaalsContact O-N 3.11Å; K501-M505 HydrophobicContact CB-CE 3.56Å; K501-M505 HydrophobicContact CD-CE 3.53Å; K501-M505 HydrophobicContact CG-CE 3.39Å
502	P	88.1	Confident	87.1	Confident	39 Å²	39	96 Å²	96	25%	0.253	47%	0.468	S	S	.	.			trans	-56.8	142.4	173.8	-23.7	33.9	0	0	0	111.2	W498 W504 M505 T506	W498-P502 HydrophobicContact CH2-CG 3.97Å; W498-P502 VanDerWaalsContact CZ2-CD 3.48Å; W498-P502 HydrophobicContact CZ2-CG 3.87Å; P502-W504 VanDerWaalsContact CB-CD1 3.43Å; P502-W504 HydrophobicContact CB-CG 4.27Å; P502-W504 PolarHBondContact O-N 3.47Å; P502-W504 VanDerWaalsContact O-N 3.11Å; P502-M505 PolarHBondContact O-N 2.88Å; P502-T506 PolarHBondContact O-N 3.47Å; P502-T506 VanDerWaalsContact O-N 3.17Å; P502-T506 PolarHBondContact O-OG1 2.93Å
503	R	85.3	Confident	87.1	Confident	229 Å²	229	96.1 Å²	96.1	86%	0.864	47%	0.471	S	S	*	.	H	α-helix	trans	-55.1	-34.5	-176.8	-70.4	-175.8	177.5	173.4	-0.6	113.4	R507	R503-R507 VanDerWaalsContact O-CB 3.23Å; R503-R507 WeakPolarHBondContact O-CB 3.24Å; R503-R507 PolarHBondContact O-N 2.95Å
504	W	90.5	Very high	87.2	Confident	192 Å²	192	91.9 Å²	91.9	73%	0.727	46%	0.456	S	S	*	.	H	α-helix	trans	-64.5	-38.6	177.7	67.6	-98	0	0	0	112.2	P502 G508	P502-W504 VanDerWaalsContact CB-CD1 3.43Å; P502-W504 HydrophobicContact CB-CG 4.27Å; P502-W504 PolarHBondContact O-N 3.47Å; P502-W504 VanDerWaalsContact O-N 3.11Å; W504-G508 PolarHBondContact O-N 3.18Å
505	M	87.6	Confident	87.4	Confident	31 Å²	31	96.4 Å²	96.4	15%	0.153	47%	0.466	C	S	.	.	H	α-helix	trans	-73.2	-44.5	-179.7	-172.8	171.8	66.6	0	0	110.8	W498 K501 P502 R507 G508 I509	W498-M505 HydrophobicContact CD2-CE 4.48Å; W498-M505 HydrophobicContact CE3-CE 3.84Å; W498-M505 HydrophobicContact CH2-CE 4.42Å; W498-M505 HydrophobicContact CZ3-CE 3.8Å; W498-M505 HydrophobicContact CZ3-SD 4.46Å; K501-M505 HydrophobicContact CB-CE 3.56Å; K501-M505 HydrophobicContact CD-CE 3.53Å; K501-M505 HydrophobicContact CG-CE 3.39Å; P502-M505 PolarHBondContact O-N 2.88Å; M505-R507 VanDerWaalsContact C-N 3.29Å; M505-R507 PolarHBondContact O-N 3.49Å; M505-G508 PolarHBondContact O-N 2.9Å; M505-I509 HydrophobicContact CG-CD1 4.25Å; M505-I509 WeakPolarHBondContact O-CG1 3.13Å; M505-I509 PolarHBondContact O-N 3.14Å
506	T	86.1	Confident	87.8	Confident	73 Å²	73	95.5 Å²	95.5	45%	0.448	45%	0.454	S	S	.	.	H	α-helix	trans	-61.5	-39.8	175	-48.1	0	0	0	0	111.3	P502 I509 F510	P502-T506 PolarHBondContact O-N 3.47Å; P502-T506 VanDerWaalsContact O-N 3.17Å; P502-T506 PolarHBondContact O-OG1 2.93Å; T506-I509 PolarHBondContact O-N 2.99Å; T506-F510 WeakPolarHBondContact O-CB 3.23Å; T506-F510 PolarHBondContact O-N 3.08Å
507	R	89.6	Confident	88.2	Confident	192 Å²	192	96.2 Å²	96.2	73%	0.725	46%	0.455	S	S	*	.	H	α-helix	trans	-64.2	-43.6	174.2	-162.5	174.8	-149.6	168.1	5.5	111.4	R503 M505 F510 T511	R503-R507 VanDerWaalsContact O-CB 3.23Å; R503-R507 WeakPolarHBondContact O-CB 3.24Å; R503-R507 PolarHBondContact O-N 2.95Å; M505-R507 VanDerWaalsContact C-N 3.29Å; M505-R507 PolarHBondContact O-N 3.49Å; R507-F510 PolarHBondContact O-N 2.94Å; R507-T511 WeakPolarHBondContact O-CB 3.43Å; R507-T511 PolarHBondContact O-N 3.48Å; R507-T511 PolarHBondContact O-OG1 3.31Å
508	G	89.8	Confident	88.5	Confident	33 Å²	33	101.9 Å²	101.9	34%	0.34	47%	0.472	S	S	.	.	H	α-helix	trans	-58.2	-50	174.4	0	0	0	0	0	112.6	W504 M505 F510 T511 T512	W504-G508 PolarHBondContact O-N 3.18Å; M505-G508 PolarHBondContact O-N 2.9Å; G508-F510 VanDerWaalsContact C-N 3.3Å; G508-F510 PolarHBondContact O-N 2.87Å; G508-T511 PolarHBondContact O-N 3.42Å; G508-T512 WeakPolarHBondContact O-CB 3.5Å; G508-T512 PolarHBondContact O-N 3.43Å; G508-T512 PolarHBondContact O-OG1 3.31Å
509	I	88.1	Confident	88.9	Confident	81 Å²	81	100.8 Å²	100.8	42%	0.415	48%	0.478	S	S	.	.	H	α-helix	trans	-57.6	-45.3	176.6	-66.3	166	0	0	0	110.6	M505 T506 T513	M505-I509 HydrophobicContact CG-CD1 4.25Å; M505-I509 WeakPolarHBondContact O-CG1 3.13Å; M505-I509 PolarHBondContact O-N 3.14Å; T506-I509 PolarHBondContact O-N 2.99Å; I509-T513 VanDerWaalsContact O-CB 3.25Å; I509-T513 WeakPolarHBondContact O-CB 3.38Å; I509-T513 PolarHBondContact O-N 3.37Å; I509-T513 PolarHBondContact O-OG1 3.4Å
510	F	89.7	Confident	89.5	Confident	148 Å²	148	94 Å²	94	65%	0.649	45%	0.45	S	S	*	.	H	α-helix	trans	-64.1	-46.5	178.3	179.7	-95.7	0	0	0	112	T506 R507 G508 T513 A514	T506-F510 WeakPolarHBondContact O-CB 3.23Å; T506-F510 PolarHBondContact O-N 3.08Å; R507-F510 PolarHBondContact O-N 2.94Å; G508-F510 VanDerWaalsContact C-N 3.3Å; G508-F510 PolarHBondContact O-N 2.87Å; F510-T513 PolarHBondContact O-N 3.36Å; F510-A514 VanDerWaalsContact O-CB 3.29Å; F510-A514 WeakPolarHBondContact O-CB 3.3Å; F510-A514 PolarHBondContact O-N 3.03Å
511	T	92.3	Very high	90	Very high	84 Å²	84	92.6 Å²	92.6	52%	0.515	44%	0.438	S	S	.	.	H	α-helix	trans	-63.3	-44.4	179.6	-57.4	0	0	0	0	111.5	R507 G508 A514 W515	R507-T511 WeakPolarHBondContact O-CB 3.43Å; R507-T511 PolarHBondContact O-N 3.48Å; R507-T511 PolarHBondContact O-OG1 3.31Å; G508-T511 PolarHBondContact O-N 3.42Å; T511-A514 PolarHBondContact O-N 3.48Å; T511-W515 VanDerWaalsContact O-CB 3.32Å; T511-W515 WeakPolarHBondContact O-CB 3.45Å; T511-W515 PolarHBondContact O-N 2.94Å
512	T	91.9	Very high	90.3	Very high	85 Å²	85	90.1 Å²	90.1	52%	0.521	43%	0.428	S	S	.	.	H	α-helix	trans	-64.1	-44.2	175.6	-55.9	0	0	0	0	111.3	G508 W515 C516	G508-T512 WeakPolarHBondContact O-CB 3.5Å; G508-T512 PolarHBondContact O-N 3.43Å; G508-T512 PolarHBondContact O-OG1 3.31Å; T512-W515 PolarHBondContact O-N 3.26Å; T512-C516 PolarHBondContact O-N 2.99Å; T512-C516 PolarHBondContact O-SG 3.28Å; T512-C516 VanDerWaalsContact O-SG 3.36Å
513	T	91.3	Very high	90.3	Very high	22 Å²	22	91.6 Å²	91.6	14%	0.135	44%	0.436	C	S	.	.	H	α-helix	trans	-61.4	-47.5	177.2	-57.6	0	0	0	0	111	L382 M385 I509 F510 W515 C516 Q517	L382-T513 HydrophobicContact CB-CG2 4.3Å; L382-T513 HydrophobicContact CD1-CG2 4.4Å; M385-T513 HydrophobicContact CE-CG2 3.76Å; I509-T513 VanDerWaalsContact O-CB 3.25Å; I509-T513 WeakPolarHBondContact O-CB 3.38Å; I509-T513 PolarHBondContact O-N 3.37Å; I509-T513 PolarHBondContact O-OG1 3.4Å; F510-T513 PolarHBondContact O-N 3.36Å; T513-W515 VanDerWaalsContact C-N 3.33Å; T513-W515 PolarHBondContact O-N 2.99Å; T513-C516 PolarHBondContact O-N 3.47Å; T513-Q517 HydrophobicContact CG2-CG 4.49Å; T513-Q517 WeakPolarHBondContact O-CB 3.32Å; T513-Q517 VanDerWaalsContact O-CG 3.3Å; T513-Q517 WeakPolarHBondContact O-CG 2.97Å; T513-Q517 PolarHBondContact O-N 3.07Å
514	A	91.3	Very high	90.2	Very high	22 Å²	22	84.6 Å²	84.6	18%	0.182	42%	0.42	C	S	.	.	H	α-helix	trans	-65	-35.2	178.3	0	0	0	0	0	112.6	F510 T511 K518	F510-A514 VanDerWaalsContact O-CB 3.29Å; F510-A514 WeakPolarHBondContact O-CB 3.3Å; F510-A514 PolarHBondContact O-N 3.03Å; T511-A514 PolarHBondContact O-N 3.48Å; A514-K518 WeakPolarHBondContact O-CG 3.35Å; A514-K518 PolarHBondContact O-N 3.45Å; A514-K518 VanDerWaalsContact O-N 3.09Å
515	W	93.6	Very high	89.4	Confident	164 Å²	164	81.4 Å²	81.4	62%	0.621	41%	0.413	S	S	*	.	H	α-helix	trans	-65.6	-49.5	173.9	-177.5	83.9	0	0	0	111	T511 T512 T513 Q517 K518 V519	T511-W515 VanDerWaalsContact O-CB 3.32Å; T511-W515 WeakPolarHBondContact O-CB 3.45Å; T511-W515 PolarHBondContact O-N 2.94Å; T512-W515 PolarHBondContact O-N 3.26Å; T513-W515 VanDerWaalsContact C-N 3.33Å; T513-W515 PolarHBondContact O-N 2.99Å; W515-Q517 VanDerWaalsContact C-N 3.32Å; W515-Q517 PolarHBondContact O-N 3.43Å; W515-K518 PolarHBondContact O-N 3.29Å; W515-K518 VanDerWaalsContact O-N 3.16Å; W515-V519 HydrophobicContact CD2-CG2 3.9Å; W515-V519 HydrophobicContact CE3-CG2 4.23Å; W515-V519 HydrophobicContact CG-CG2 4.46Å; W515-V519 HydrophobicContact CH2-CG2 4.1Å; W515-V519 HydrophobicContact CZ2-CG2 3.75Å; W515-V519 HydrophobicContact CZ3-CG2 4.32Å; W515-V519 WeakPolarHBondContact O-CG2 3.18Å; W515-V519 PolarHBondContact O-N 3.18Å
516	C	91.8	Very high	88.2	Confident	15 Å²	15	89 Å²	89	10%	0.101	45%	0.448	C	S	.	.	H	α-helix	trans	-60.5	-40.2	175.9	-68.6	0	0	0	0	112.2	L382 T512 T513 K518 V519 M520	L382-C516 HydrophobicContact CD1-CB 3.66Å; L382-C516 HydrophobicContact CD2-CB 3.57Å; L382-C516 HydrophobicContact CG-CB 4.27Å; T512-C516 PolarHBondContact O-N 2.99Å; T512-C516 PolarHBondContact O-SG 3.28Å; T512-C516 VanDerWaalsContact O-SG 3.36Å; T513-C516 PolarHBondContact O-N 3.47Å; C516-K518 VanDerWaalsContact C-N 3.33Å; C516-K518 PolarHBondContact O-N 3.47Å; C516-V519 PolarHBondContact O-N 3.41Å; C516-M520 VanDerWaalsContact O-CB 3.29Å; C516-M520 WeakPolarHBondContact O-CB 3.28Å; C516-M520 WeakPolarHBondContact O-CG 3.35Å; C516-M520 PolarHBondContact O-N 3.1Å
517	Q	91.5	Very high	86.1	Confident	52 Å²	52	94.4 Å²	94.4	24%	0.243	49%	0.489	C	S	.	.	H	α-helix	trans	-57.3	-44.4	174.2	-80.3	179.5	-35.8	0	0	112.3	L382 M385 T513 W515 E521 V522	L382-Q517 HydrophobicContact CD1-CG 4.47Å; M385-Q517 HydrophobicContact CE-CG 4.16Å; M385-Q517 HydrophobicContact SD-CG 3.42Å; M385-Q517 WeakPolarHBondContact SD-CG 3.42Å; M385-Q517 PolarHBondContact SD-NE2 3.18Å; T513-Q517 HydrophobicContact CG2-CG 4.49Å; T513-Q517 WeakPolarHBondContact O-CB 3.32Å; T513-Q517 VanDerWaalsContact O-CG 3.3Å; T513-Q517 WeakPolarHBondContact O-CG 2.97Å; T513-Q517 PolarHBondContact O-N 3.07Å; W515-Q517 VanDerWaalsContact C-N 3.32Å; W515-Q517 PolarHBondContact O-N 3.43Å; Q517-E521 WeakPolarHBondContact O-CA 3.29Å; Q517-E521 PolarHBondContact O-N 3.2Å; Q517-V522 HydrophobicContact CG-CG2 4.24Å; Q517-V522 PolarHBondContact O-N 3.01Å; Q517-V522 VanDerWaalsContact O-N 3.13Å
518	K	91.6	Very high	85.9	Confident	178 Å²	178	89.5 Å²	89.5	77%	0.774	48%	0.478	S	S	*	.	H	α-helix	trans	-70.6	-40	178.4	-72.7	177.4	-179.4	-173.4	0	112.7	A514 W515 C516	A514-K518 WeakPolarHBondContact O-CG 3.35Å; A514-K518 PolarHBondContact O-N 3.45Å; A514-K518 VanDerWaalsContact O-N 3.09Å; W515-K518 PolarHBondContact O-N 3.29Å; W515-K518 VanDerWaalsContact O-N 3.16Å; C516-K518 VanDerWaalsContact C-N 3.33Å; C516-K518 PolarHBondContact O-N 3.47Å
519	V	93.4	Very high	85.7	Confident	87 Å²	87	92.5 Å²	92.5	53%	0.527	49%	0.485	S	S	.	.	H	α-helix	trans	-69	-40.7	-179.2	170.1	0	0	0	0	111.5	W515 C516	W515-V519 HydrophobicContact CD2-CG2 3.9Å; W515-V519 HydrophobicContact CE3-CG2 4.23Å; W515-V519 HydrophobicContact CG-CG2 4.46Å; W515-V519 HydrophobicContact CH2-CG2 4.1Å; W515-V519 HydrophobicContact CZ2-CG2 3.75Å; W515-V519 HydrophobicContact CZ3-CG2 4.32Å; W515-V519 WeakPolarHBondContact O-CG2 3.18Å; W515-V519 PolarHBondContact O-N 3.18Å; C516-V519 PolarHBondContact O-N 3.41Å
520	M	90.6	Very high	85.5	Confident	44 Å²	44	93.1 Å²	93.1	22%	0.217	49%	0.489	C	S	.	.	H	α-helix	trans	-95.8	-5.4	-175.4	-63.9	-178.3	-172.9	0	0	113.3	H387 L394 P395 I398 C516 V522	H387-M520 PolarHBondContact CD2-O 3.03Å; L394-M520 HydrophobicContact CD2-CB 3.59Å; L394-M520 HydrophobicContact CD2-CG 3.74Å; L394-M520 HydrophobicContact CD2-SD 4.04Å; P395-M520 HydrophobicContact CB-SD 4.14Å; P395-M520 HydrophobicContact CG-SD 3.97Å; I398-M520 HydrophobicContact CD1-CE 4.01Å; I398-M520 HydrophobicContact CD1-SD 4.13Å; C516-M520 VanDerWaalsContact O-CB 3.29Å; C516-M520 WeakPolarHBondContact O-CB 3.28Å; C516-M520 WeakPolarHBondContact O-CG 3.35Å; C516-M520 PolarHBondContact O-N 3.1Å; M520-V522 HydrophobicContact CB-CG1 3.87Å; M520-V522 HydrophobicContact CB-CG2 4.16Å; M520-V522 WeakPolarHBondContact O-CG1 3.41Å; M520-V522 PolarHBondContact O-N 3.33Å
521	E	91.8	Very high	85.3	Confident	116 Å²	116	89.9 Å²	89.9	54%	0.542	48%	0.479	S	S	.	.	T	Hydrogen-bonded Turn	trans	48.6	56.7	-172.2	-160.8	-178.2	167	0	0	111.6	H387 P388 Q517	H387-E521 PolarHBondContact CD2-O 3.08Å; P388-E521 WeakPolarHBondContact CD-O 3.4Å; P388-E521 HydrophobicContact CG-CG 4.32Å; Q517-E521 WeakPolarHBondContact O-CA 3.29Å; Q517-E521 PolarHBondContact O-N 3.2Å
522	V	89.7	Confident	84.9	Confident	6 Å²	6	90.3 Å²	90.3	4%	0.036	48%	0.477	C	S	.	.			trans	-116.2	142.1	-177.4	-64	0	0	0	0	112.2	L382 M385 I386 L394 P395 Q517 M520	L382-V522 HydrophobicContact CD1-CG2 4.36Å; M385-V522 HydrophobicContact CB-CB 3.8Å; M385-V522 HydrophobicContact CB-CG2 3.78Å; M385-V522 HydrophobicContact SD-CG2 4.08Å; I386-V522 WeakPolarHBondContact O-CA 3.38Å; L394-V522 HydrophobicContact CB-CG1 4.14Å; P395-V522 HydrophobicContact CG-CB 4.41Å; P395-V522 HydrophobicContact CG-CG1 4.04Å; P395-V522 HydrophobicContact CG-CG2 3.98Å; Q517-V522 HydrophobicContact CG-CG2 4.24Å; Q517-V522 PolarHBondContact O-N 3.01Å; Q517-V522 VanDerWaalsContact O-N 3.13Å; M520-V522 HydrophobicContact CB-CG1 3.87Å; M520-V522 HydrophobicContact CB-CG2 4.16Å; M520-V522 WeakPolarHBondContact O-CG1 3.41Å; M520-V522 PolarHBondContact O-N 3.33Å
523	V	88.4	Confident	84.4	Confident	70 Å²	70	90.6 Å²	90.6	42%	0.424	47%	0.474	S	S	.	.	B	Isolated β-bridge	trans	-115.8	148.8	-179.5	-64.8	0	0	0	0	111.2	M385 I386 P388	M385-V523 CarbonylContact C-O 3.45Å; M385-V523 VanDerWaalsContact CA-O 3.3Å; M385-V523 WeakPolarHBondContact CA-O 3.28Å; M385-V523 WeakPolarHBondContact CB-O 3.34Å; I386-V523 PolarHBondContact N-O 3.23Å; I386-V523 WeakPolarHBondContact O-CG2 3.5Å; I386-V523 PolarHBondContact O-N 3.39Å; P388-V523 HydrophobicContact CB-CG2 4.39Å
524	P	83.9	Confident	83.9	Confident	82 Å²	82	95.5 Å²	95.5	53%	0.532	50%	0.498	S	S	.	.	P	Polyproline II helix	trans	-59.9	153	168.9	-16.9	30.1	0	0	0	111.2	M385	M385-P524 HydrophobicContact CE-CG 4.3Å
525	Q	72.4	Confident	83.3	Confident	124 Å²	124	101.2 Å²	101.2	58%	0.579	52%	0.523	S	S	*	.	P	Polyproline II helix	trans	-68.3	139.3	171.7	-171.5	177.7	-2.4	0	0	110.1	S527	Q525-S527 PolarHBondContact O-N 3.01Å
526	E	63.3	Low	82.5	Confident	190 Å²	190	95.9 Å²	95.9	89%	0.888	51%	0.514	S	S	*	.	P	Polyproline II helix	trans	-63	118.8	167.5	-71.3	-175.9	166.5	0	0	108.6
527	S	41.3	Very low	81.6	Confident	187 Å²	187	103.3 Å²	103.3	100%	1.308	55%	0.552	S	S	*	*			trans	-84	0	-176.4	56.9	0	0	0	0	112.5	Q525	Q525-S527 PolarHBondContact O-N 3.01Å

Retrieved 527 of 527 residues in 215.3 ms (Link to these results)

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