A0A087XMD0_POEFO Loading...

Heat shock protein 4a

AlphaFold DB , UniProt , Accession A0A087XMD0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 836 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M73Confident93.1Very high99 Ų9918.9 Ų18.949%0.48810%0.101SC..  0134.90-176.3169.4-73.500108.4D139 S384M1-D139 HydrophobicContact CE-CB 4.37Å; M1-D139 HydrophobicContact CG-CB 4.15Å; M1-D139 WeakPolarHBondContact CG-OD2 3.46Å; M1-D139 HydrophobicContact SD-CB 4.37Å; M1-S384 PolarHBondContact SD-OG 2.9Å
2S86.4Confident93.3Very high18 Ų1819.4 Ų19.413%0.12611%0.107CC..  trans-97.3138.7171.6-64.40000107.9P136S2-P136 PolarHBondContact OG-O 3.24Å
3V92.3Very high93.6Very high3 Ų317.9 Ų17.92%0.01810%0.099CC..  trans-100.3113.6178.61650000108.6V17 A18 I23 A377 C380 A381 F387V3-V17 WeakPolarHBondContact O-CA 3.39Å; V3-A18 HydrophobicContact CB-CB 3.79Å; V3-A18 HydrophobicContact CG1-CB 3.77Å; V3-A18 PolarHBondContact O-N 2.9Å; V3-I23 HydrophobicContact CG1-CD1 4.4Å; V3-A377 VanDerWaalsContact CG1-O 3.31Å; V3-A377 WeakPolarHBondContact CG1-O 3.43Å; V3-C380 HydrophobicContact CG1-CB 4.06Å; V3-A381 HydrophobicContact CG1-CB 3.9Å; V3-A381 HydrophobicContact CG2-CB 4.43Å; V3-F387 HydrophobicContact CB-CE2 4.3Å; V3-F387 HydrophobicContact CB-CZ 4.5Å; V3-F387 HydrophobicContact CG2-CD2 3.42Å; V3-F387 VanDerWaalsContact CG2-CD2 3.42Å; V3-F387 HydrophobicContact CG2-CE2 3.52Å; V3-F387 HydrophobicContact CG2-CG 3.97Å; V3-F387 HydrophobicContact CG2-CZ 4.13Å
4V97.5Very high94Very high0 Ų018.8 Ų18.80%010%0.1CC..EExtended strand (participates in β ladder)trans-138.5130.2-175.6-172.70000111F6 V15 A16 V17 A129 L133 V137 C140 V141 C380V4-F6 HydrophobicContact CG1-CD1 4.03Å; V4-F6 HydrophobicContact CG1-CE1 3.46Å; V4-F6 VanDerWaalsContact CG1-CE1 3.46Å; V4-F6 HydrophobicContact CG1-CE2 4.02Å; V4-F6 HydrophobicContact CG1-CZ 3.47Å; V4-F6 VanDerWaalsContact CG1-CZ 3.47Å; V4-V15 HydrophobicContact CG1-CG1 4.15Å; V4-A16 WeakPolarHBondContact CA-O 3.5Å; V4-V17 HydrophobicContact CG1-CG1 4.46Å; V4-V17 HydrophobicContact CG2-CG1 4.26Å; V4-A129 HydrophobicContact CG1-CB 3.8Å; V4-A129 HydrophobicContact CG2-CB 4.05Å; V4-L133 HydrophobicContact CG2-CD1 3.96Å; V4-V137 HydrophobicContact CB-CG1 4.2Å; V4-V137 HydrophobicContact CG2-CB 4.42Å; V4-V137 HydrophobicContact CG2-CG1 3.69Å; V4-V137 HydrophobicContact CG2-CG2 3.76Å; V4-C140 WeakPolarHBondContact O-CA 3.36Å; V4-V141 PolarHBondContact O-N 3.46Å; V4-V141 VanDerWaalsContact O-N 3.08Å; V4-C380 PolarHBondContact N-SG 2.98Å; V4-C380 VanDerWaalsContact N-SG 3.41Å
5G98.3Very high94.3Very high0 Ų017.6 Ų17.60%09%0.094CC..EExtended strand (participates in β ladder)trans-113.4128.5169.900000110.6A16 V141G5-A16 PolarHBondContact N-O 2.89Å; G5-A16 PolarHBondContact O-N 2.77Å; G5-V141 WeakPolarHBondContact CA-O 3.47Å
6F98.6Very high94.5Very high0 Ų016.5 Ų16.50%09%0.088CC..EExtended strand (participates in β ladder)trans-107.2120.8173.6-60.9-55000109.5V4 V15 L122 L125 K126 A129 C140 V141 I142 S143 L165V4-F6 HydrophobicContact CG1-CD1 4.03Å; V4-F6 HydrophobicContact CG1-CE1 3.46Å; V4-F6 VanDerWaalsContact CG1-CE1 3.46Å; V4-F6 HydrophobicContact CG1-CE2 4.02Å; V4-F6 HydrophobicContact CG1-CZ 3.47Å; V4-F6 VanDerWaalsContact CG1-CZ 3.47Å; F6-V15 HydrophobicContact CD1-CB 4.46Å; F6-V15 HydrophobicContact CD1-CG1 4.09Å; F6-V15 HydrophobicContact CD1-CG2 4.03Å; F6-V15 HydrophobicContact CE1-CG1 3.83Å; F6-V15 HydrophobicContact CE1-CG2 4.14Å; F6-L122 HydrophobicContact CD2-CD2 4.4Å; F6-L125 HydrophobicContact CB-CD1 4.37Å; F6-L125 HydrophobicContact CD1-CB 3.65Å; F6-L125 HydrophobicContact CD1-CD1 4.14Å; F6-L125 HydrophobicContact CE1-CB 3.54Å; F6-L125 WeakPolarHBondContact CE1-O 3.49Å; F6-L125 HydrophobicContact CG-CB 4.45Å; F6-L125 HydrophobicContact CG-CD1 4.41Å; F6-L125 HydrophobicContact CZ-CB 4.26Å; F6-K126 HydrophobicContact CZ-CB 4.5Å; F6-A129 HydrophobicContact CE1-CB 4.38Å; F6-C140 HydrophobicContact CD2-CB 3.78Å; F6-C140 HydrophobicContact CE2-CB 3.54Å; F6-V141 PolarHBondContact N-O 2.83Å; F6-I142 HydrophobicContact CB-CG1 4.33Å; F6-I142 HydrophobicContact CD2-CG1 4.01Å; F6-S143 PolarHBondContact O-N 2.81Å; F6-L165 HydrophobicContact CD2-CD1 4.49Å; F6-L165 HydrophobicContact CE2-CD1 3.76Å; F6-L165 HydrophobicContact CE2-CD2 4.25Å; F6-L165 HydrophobicContact CZ-CD1 4.48Å
7D98.3Very high94.6Very high15 Ų1515.5 Ų15.58%0.088%0.083CC..EExtended strand (participates in β ladder)trans-85.4119.3154.2179.938.3000109.1C13 Y14 S143 V372 A373D7-C13 CarbonylContact O-C 3.56Å; D7-C13 WeakPolarHBondContact O-CA 3.49Å; D7-C13 WeakPolarHBondContact O-CB 3.5Å; D7-Y14 PolarHBondContact N-O 3.38Å; D7-Y14 PolarHBondContact O-N 3.06Å; D7-S143 WeakPolarHBondContact CA-OG 3.36Å; D7-S143 PolarHBondContact OD1-OG 3.04Å; D7-V372 HydrophobicContact CB-CB 3.99Å; D7-V372 HydrophobicContact CB-CG1 3.89Å; D7-V372 VanDerWaalsContact OD1-CG1 3.23Å; D7-V372 WeakPolarHBondContact OD1-CG1 3.44Å; D7-A373 HydrophobicContact CB-CB 3.82Å
8L96.8Very high94.5Very high0 Ų015.5 Ų15.50%09%0.085CC..  trans-104.954.8-175.5-170.169.1000110K68 T118 L121 L122 L125 I142 S143 V156L8-K68 HydrophobicContact CG-CD 4.16Å; L8-K68 WeakPolarHBondContact O-CD 3.22Å; L8-K68 VanDerWaalsContact O-CE 3.27Å; L8-K68 WeakPolarHBondContact O-CE 3.37Å; L8-K68 PolarHBondContact O-NZ 3.36Å; L8-T118 HydrophobicContact CD2-CG2 3.87Å; L8-L121 HydrophobicContact CD1-CD2 4.03Å; L8-L121 HydrophobicContact CD1-CG 4.32Å; L8-L122 HydrophobicContact CD1-CD2 3.99Å; L8-L122 HydrophobicContact CD1-CG 4.34Å; L8-L122 HydrophobicContact CD2-CD2 4.48Å; L8-L125 HydrophobicContact CD1-CD1 4.11Å; L8-I142 HydrophobicContact CB-CG2 4.17Å; L8-I142 HydrophobicContact CD2-CG2 4Å; L8-S143 PolarHBondContact N-OG 3.27Å; L8-V156 HydrophobicContact CD2-CG1 4.26Å
9G94.4Very high94.1Very high12 Ų1220.7 Ų20.712%0.12410%0.104CC..  trans-64.8161.8-174.500000114.8Q11 S12 S37G9-Q11 VanDerWaalsContact C-N 3.32Å; G9-Q11 PolarHBondContact O-N 2.83Å; G9-S12 CarbonylContact C-O 3.53Å; G9-S12 WeakPolarHBondContact CA-O 3.29Å; G9-S12 PolarHBondContact N-O 3.37Å; G9-S37 PolarHBondContact O-OG 2.92Å
10F94.1Very high93.4Very high22 Ų2225.2 Ų25.210%0.09614%0.144CC..SBendtrans-66-26.2-175-80-86.2000115.4K68 R69 P145 Y148 H205F10-K68 HydrophobicContact CD1-CB 3.68Å; F10-K68 HydrophobicContact CE1-CB 3.67Å; F10-R69 HydrophobicContact CE1-CB 3.96Å; F10-P145 HydrophobicContact CE2-CG 3.89Å; F10-P145 HydrophobicContact CZ-CG 4.34Å; F10-Y148 HydrophobicContact CZ-CE1 4.36Å; F10-H205 HydrophobicContact CB-CB 4.34Å
11Q94.2Very high92.8Very high39 Ų3928.5 Ų28.518%0.18218%0.183CC..SBendtrans-120.1-32.9-178.1-167-163.117.100112.5G9 P36 S37 H205 E271G9-Q11 VanDerWaalsContact C-N 3.32Å; G9-Q11 PolarHBondContact O-N 2.83Å; Q11-P36 WeakPolarHBondContact O-CA 3.31Å; Q11-S37 VanDerWaalsContact C-OG 3.27Å; Q11-S37 PolarHBondContact O-N 3.35Å; Q11-H205 HydrophobicContact CB-CB 3.79Å; Q11-H205 PolarHBondContact OE1-CD2 3.32Å; Q11-E271 PolarHBondContact NE2-OE1 2.98Å; Q11-E271 PolarHBondContact NE2-OE2 2.84Å
12S95.1Very high93.6Very high25 Ų2525.4 Ų25.418%0.17518%0.177CC..EExtended strand (participates in β ladder)trans-142141.4-172.7-61.70000108.6G9 C34 S37G9-S12 CarbonylContact C-O 3.53Å; G9-S12 WeakPolarHBondContact CA-O 3.29Å; G9-S12 PolarHBondContact N-O 3.37Å; S12-C34 WeakPolarHBondContact CB-SG 3.44Å; S12-C34 PolarHBondContact OG-SG 3.34Å; S12-S37 PolarHBondContact N-OG 2.89Å
13C97.9Very high93.9Very high0 Ų025.5 Ų25.50%018%0.176CC..EExtended strand (participates in β ladder)trans-117.2149173.7-63.50000109.9D7 T35 S37 L125D7-C13 CarbonylContact O-C 3.56Å; D7-C13 WeakPolarHBondContact O-CA 3.49Å; D7-C13 WeakPolarHBondContact O-CB 3.5Å; C13-T35 PolarHBondContact N-O 2.72Å; C13-T35 PolarHBondContact O-N 3.22Å; C13-S37 PolarHBondContact SG-OG 2.98Å; C13-L125 HydrophobicContact CB-CD1 3.73Å; C13-L125 HydrophobicContact CB-CD2 3.71Å; C13-L125 HydrophobicContact CB-CG 4.34Å
14Y98.4Very high94Very high30 Ų3028.2 Ų28.212%0.11819%0.188CC..EExtended strand (participates in β ladder)trans-126.9141177.7-62.5-88.2000110.3D7 R33 C34 D369 A373D7-Y14 PolarHBondContact N-O 3.38Å; D7-Y14 PolarHBondContact O-N 3.06Å; Y14-R33 WeakPolarHBondContact CD1-O 3.38Å; Y14-C34 HydrophobicContact CE1-CB 3.72Å; Y14-D369 WeakPolarHBondContact CD2-O 3.24Å; Y14-D369 HydrophobicContact CE1-CB 4.22Å; Y14-D369 HydrophobicContact CE2-CB 4.11Å; Y14-A373 WeakPolarHBondContact O-CB 3.34Å
15V98.5Very high94Very high1 Ų128.4 Ų28.41%0.00619%0.19CC..EExtended strand (participates in β ladder)trans-113.1126.7179.6-174.90000108.6V4 F6 V17 T25 V26 L125 T128 A129V4-V15 HydrophobicContact CG1-CG1 4.15Å; F6-V15 HydrophobicContact CD1-CB 4.46Å; F6-V15 HydrophobicContact CD1-CG1 4.09Å; F6-V15 HydrophobicContact CD1-CG2 4.03Å; F6-V15 HydrophobicContact CE1-CG1 3.83Å; F6-V15 HydrophobicContact CE1-CG2 4.14Å; V15-V17 HydrophobicContact CG1-CG1 4.37Å; V15-T25 CarbonylContact O-C 3.55Å; V15-T25 VanDerWaalsContact O-CA 3.23Å; V15-T25 WeakPolarHBondContact O-CA 3.42Å; V15-V26 HydrophobicContact CB-CG2 3.7Å; V15-V26 HydrophobicContact CG1-CG2 3.63Å; V15-V26 PolarHBondContact O-N 3.36Å; V15-L125 HydrophobicContact CG2-CB 3.98Å; V15-L125 HydrophobicContact CG2-CD2 3.8Å; V15-L125 HydrophobicContact CG2-CG 4.38Å; V15-T128 HydrophobicContact CG2-CG2 4.23Å; V15-A129 HydrophobicContact CG1-CB 3.86Å
16A98.1Very high93.9Very high0 Ų028.9 Ų28.90%019%0.193CC..EExtended strand (participates in β ladder)trans-120.8145.2171.400000111.3V4 G5 I23 E24 T25 A373 A377V4-A16 WeakPolarHBondContact CA-O 3.5Å; G5-A16 PolarHBondContact N-O 2.89Å; G5-A16 PolarHBondContact O-N 2.77Å; A16-I23 HydrophobicContact CB-CG2 4.25Å; A16-E24 CarbonylContact C-O 3.6Å; A16-E24 WeakPolarHBondContact CA-O 3.36Å; A16-T25 HydrophobicContact CB-CG2 4.1Å; A16-A373 HydrophobicContact CB-CB 3.95Å; A16-A373 WeakPolarHBondContact CB-O 3.3Å; A16-A377 HydrophobicContact CB-CB 3.69Å
17V96.8Very high93.9Very high0 Ų031.1 Ų31.10%021%0.211CC..EExtended strand (participates in β ladder)trans-136.3162-178.5-510000111.1V3 V4 V15 I23 E24 V26 A129 L133V3-V17 WeakPolarHBondContact O-CA 3.39Å; V4-V17 HydrophobicContact CG1-CG1 4.46Å; V4-V17 HydrophobicContact CG2-CG1 4.26Å; V15-V17 HydrophobicContact CG1-CG1 4.37Å; V17-I23 WeakPolarHBondContact O-CA 3.17Å; V17-E24 HydrophobicContact CG2-CG 4.48Å; V17-E24 PolarHBondContact N-O 2.67Å; V17-E24 PolarHBondContact O-N 3.3Å; V17-E24 VanDerWaalsContact O-N 3.07Å; V17-V26 HydrophobicContact CB-CG1 4.49Å; V17-V26 HydrophobicContact CG1-CG1 4.15Å; V17-V26 HydrophobicContact CG1-CG2 4.4Å; V17-V26 HydrophobicContact CG2-CG1 3.59Å; V17-A129 HydrophobicContact CG1-CB 4.34Å; V17-L133 HydrophobicContact CB-CD1 4.25Å; V17-L133 HydrophobicContact CB-CD2 4.01Å; V17-L133 HydrophobicContact CB-CG 4.22Å; V17-L133 HydrophobicContact CG1-CD1 4.13Å; V17-L133 HydrophobicContact CG1-CG 4.2Å; V17-L133 HydrophobicContact CG2-CD2 3.89Å; V17-L133 HydrophobicContact CG2-CG 4.36Å
18A92.9Very high93.8Very high15 Ų1530.9 Ų30.912%0.12421%0.21CC..EExtended strand (participates in β ladder)trans-84.2122.6166.200000111.3V3 G22 I23 F387V3-A18 HydrophobicContact CB-CB 3.79Å; V3-A18 HydrophobicContact CG1-CB 3.77Å; V3-A18 PolarHBondContact O-N 2.9Å; A18-G22 WeakPolarHBondContact CA-O 3.43Å; A18-I23 HydrophobicContact CB-CD1 3.75Å; A18-F387 HydrophobicContact CB-CD1 4.3Å; A18-F387 HydrophobicContact CB-CE1 3.7Å; A18-F387 HydrophobicContact CB-CZ 4.13Å
19R85.9Confident93.6Very high115 Ų11535.7 Ų35.743%0.43423%0.232SC..EExtended strand (participates in β ladder)trans-143.3143.9173.9-165.1-170.9-78.4160.8-16.7109.7G21 G22 E24 A132R19-G21 PolarHBondContact O-N 2.82Å; R19-G22 PolarHBondContact N-O 3.33Å; R19-G22 CarbonylContact O-C 3.51Å; R19-G22 PolarHBondContact O-N 2.98Å; R19-G22 VanDerWaalsContact O-O 3.09Å; R19-E24 HydrophobicContact CB-CG 4.28Å; R19-E24 WeakPolarHBondContact CD-OE1 3.35Å; R19-E24 IonicContact CZ-OE1 3.63Å; R19-E24 IonicContact NE-OE1 2.73Å; R19-E24 PolarHBondContact NE-OE1 2.73Å; R19-E24 IonicContact NH1-OE1 2.69Å; R19-E24 PolarHBondContact NH1-OE1 2.84Å; R19-A132 PolarHBondContact NH2-O 3.3Å
20A81.2Confident93.6Very high110 Ų11041.2 Ų41.291%0.90925%0.25SS*.THydrogen-bonded Turntrans51.231.817400000115.7G22A20-G22 VanDerWaalsContact C-N 3.3Å; A20-G22 PolarHBondContact O-N 3.03Å
21G80.4Confident93.7Very high94 Ų9445.1 Ų45.197%0.96928%0.28SS*.THydrogen-bonded Turntrans82.1-1.6-178.100000115.4R19R19-G21 PolarHBondContact O-N 2.82Å
22G88.6Confident93.8Very high35 Ų3547.6 Ų47.636%0.36130%0.295SS..EExtended strand (participates in β ladder)trans-117.7179.7175.800000113.6A18 R19 A20A18-G22 WeakPolarHBondContact CA-O 3.43Å; R19-G22 PolarHBondContact N-O 3.33Å; R19-G22 CarbonylContact O-C 3.51Å; R19-G22 PolarHBondContact O-N 2.98Å; R19-G22 VanDerWaalsContact O-O 3.09Å; A20-G22 VanDerWaalsContact C-N 3.3Å; A20-G22 PolarHBondContact O-N 3.03Å
23I94.1Very high93.9Very high19 Ų1952.2 Ų52.210%0.09731%0.308CS..EExtended strand (participates in β ladder)trans-111.2127.4169.4-60.5-57.8000108.6V3 A16 V17 A18 R374 A377 L378V3-I23 HydrophobicContact CG1-CD1 4.4Å; A16-I23 HydrophobicContact CB-CG2 4.25Å; V17-I23 WeakPolarHBondContact O-CA 3.17Å; A18-I23 HydrophobicContact CB-CD1 3.75Å; I23-R374 HydrophobicContact CG2-CB 4.36Å; I23-R374 HydrophobicContact CG2-CG 4.38Å; I23-R374 PolarHBondContact O-NH1 3.27Å; I23-A377 HydrophobicContact CD1-CB 4.28Å; I23-A377 HydrophobicContact CG2-CB 3.64Å; I23-L378 HydrophobicContact CG1-CD2 3.67Å; I23-L378 HydrophobicContact CG1-CG 3.96Å
24E94.4Very high93.8Very high60 Ų6053.7 Ų53.728%0.2832%0.318SS..EExtended strand (participates in β ladder)trans-135.3152.117960.5172.8-163.200111.7A16 V17 R19A16-E24 CarbonylContact C-O 3.6Å; A16-E24 WeakPolarHBondContact CA-O 3.36Å; V17-E24 HydrophobicContact CG2-CG 4.48Å; V17-E24 PolarHBondContact N-O 2.67Å; V17-E24 PolarHBondContact O-N 3.3Å; V17-E24 VanDerWaalsContact O-N 3.07Å; R19-E24 HydrophobicContact CB-CG 4.28Å; R19-E24 WeakPolarHBondContact CD-OE1 3.35Å; R19-E24 IonicContact CZ-OE1 3.63Å; R19-E24 IonicContact NE-OE1 2.73Å; R19-E24 PolarHBondContact NE-OE1 2.73Å; R19-E24 IonicContact NH1-OE1 2.69Å; R19-E24 PolarHBondContact NH1-OE1 2.84Å
25T96.7Very high93.7Very high5 Ų552.4 Ų52.43%0.03131%0.314CS..EExtended strand (participates in β ladder)trans-85.9133.9170.348.50000111.1V15 A16 R33 E370 R374V15-T25 CarbonylContact O-C 3.55Å; V15-T25 VanDerWaalsContact O-CA 3.23Å; V15-T25 WeakPolarHBondContact O-CA 3.42Å; A16-T25 HydrophobicContact CB-CG2 4.1Å; T25-R33 PolarHBondContact OG1-NH1 2.84Å; T25-E370 HydrophobicContact CG2-CB 3.74Å; T25-E370 HydrophobicContact CG2-CG 3.71Å; T25-E370 PolarHBondContact OG1-OE1 3.26Å; T25-E370 PolarHBondContact OG1-OE2 2.92Å; T25-R374 HydrophobicContact CG2-CG 4.13Å
26V97.1Very high93.7Very high10 Ų1052.8 Ų52.86%0.06132%0.316CS..PPolyproline II helixtrans-99.8151.9-176.3-61.20000111.4V15 V17 T128 A132V15-V26 HydrophobicContact CB-CG2 3.7Å; V15-V26 HydrophobicContact CG1-CG2 3.63Å; V15-V26 PolarHBondContact O-N 3.36Å; V17-V26 HydrophobicContact CB-CG1 4.49Å; V17-V26 HydrophobicContact CG1-CG1 4.15Å; V17-V26 HydrophobicContact CG1-CG2 4.4Å; V17-V26 HydrophobicContact CG2-CG1 3.59Å; V26-T128 HydrophobicContact CG2-CG2 4.02Å; V26-A132 HydrophobicContact CB-CB 3.8Å; V26-A132 HydrophobicContact CG1-CB 3.61Å; V26-A132 HydrophobicContact CG2-CB 4.11Å
27A97.3Very high93.7Very high46 Ų4652.9 Ų52.938%0.3832%0.317SS..PPolyproline II helixtrans-85.2152.8173.700000111.8S31 D32 T128A27-S31 WeakPolarHBondContact CB-O 3.5Å; A27-D32 CarbonylContact C-O 3.57Å; A27-D32 VanDerWaalsContact CA-O 3.31Å; A27-D32 WeakPolarHBondContact CA-O 3.49Å; A27-T128 WeakPolarHBondContact O-CG2 3.49Å
28N96.1Very high93.7Very high11 Ų1153.4 Ų53.46%0.05932%0.319CS..  trans-81-176167.265.933.3000111.5Y30 S31 D32 C34 T35 T128N28-Y30 PolarHBondContact O-N 3.49Å; N28-Y30 VanDerWaalsContact O-N 3.15Å; N28-Y30 WeakPolarHBondContact OD1-CA 3.34Å; N28-Y30 WeakPolarHBondContact OD1-CB 3.32Å; N28-Y30 PolarHBondContact OD1-N 3.32Å; N28-S31 PolarHBondContact O-N 2.76Å; N28-D32 PolarHBondContact N-O 2.81Å; N28-D32 PolarHBondContact ND2-O 2.94Å; N28-D32 PolarHBondContact OD1-N 2.81Å; N28-D32 PolarHBondContact OD1-O 2.83Å; N28-C34 PolarHBondContact ND2-O 2.97Å; N28-T35 PolarHBondContact ND2-OG1 2.76Å; N28-T128 HydrophobicContact CB-CG2 4.33Å
29E93.9Very high94Very high100 Ų10052.7 Ų52.747%0.46731%0.313SS..THydrogen-bonded Turntrans-63.3-15.3-178.868.4-78.4-175.100115.3S31 K124E29-S31 VanDerWaalsContact C-N 3.33Å; E29-K124 VanDerWaalsContact OE1-CE 3.3Å; E29-K124 WeakPolarHBondContact OE1-CE 3.33Å; E29-K124 IonicContact OE1-NZ 2.64Å; E29-K124 PolarHBondContact OE1-NZ 3.48Å; E29-K124 IonicContact OE2-NZ 3.14Å; E29-K124 PolarHBondContact OE2-NZ 3.07Å
30Y94.3Very high94.5Very high128 Ų12847.2 Ų47.250%0.50229%0.292SS..THydrogen-bonded Turntrans-93.39.9173.6-63.1-88.8000112.6N28 D32 A50N28-Y30 PolarHBondContact O-N 3.49Å; N28-Y30 VanDerWaalsContact O-N 3.15Å; N28-Y30 WeakPolarHBondContact OD1-CA 3.34Å; N28-Y30 WeakPolarHBondContact OD1-CB 3.32Å; N28-Y30 PolarHBondContact OD1-N 3.32Å; Y30-D32 PolarHBondContact O-N 3.37Å; Y30-A50 HydrophobicContact CD2-CB 3.49Å; Y30-A50 VanDerWaalsContact CD2-CB 3.49Å; Y30-A50 HydrophobicContact CE2-CB 3.66Å; Y30-A50 HydrophobicContact CG-CB 4.15Å
31S96.5Very high95.4Very high104 Ų10442 Ų4273%0.72725%0.249SC*.SBendtrans64.85.1-171.7-560000115.7A27 N28 E29A27-S31 WeakPolarHBondContact CB-O 3.5Å; N28-S31 PolarHBondContact O-N 2.76Å; E29-S31 VanDerWaalsContact C-N 3.33Å
32D96.4Very high96.1Very high92 Ų9238.2 Ų38.249%0.49221%0.21SC..  trans-78132.3173.4-92.2-38.7000111.5A27 N28 Y30 C34A27-D32 CarbonylContact C-O 3.57Å; A27-D32 VanDerWaalsContact CA-O 3.31Å; A27-D32 WeakPolarHBondContact CA-O 3.49Å; N28-D32 PolarHBondContact N-O 2.81Å; N28-D32 PolarHBondContact ND2-O 2.94Å; N28-D32 PolarHBondContact OD1-N 2.81Å; N28-D32 PolarHBondContact OD1-O 2.83Å; Y30-D32 PolarHBondContact O-N 3.37Å; D32-C34 PolarHBondContact O-N 2.84Å
33R96.2Very high96.4Very high122 Ų12240.4 Ų40.446%0.4622%0.218SC..SBendtrans-68.4-19.1167.2-70.8-177.1176.2-174.23.6113Y14 T25 E370Y14-R33 WeakPolarHBondContact CD1-O 3.38Å; T25-R33 PolarHBondContact OG1-NH1 2.84Å; R33-E370 WeakPolarHBondContact CD-OE1 3.33Å; R33-E370 IonicContact CZ-OE1 2.66Å; R33-E370 IonicContact NE-OE1 3.59Å; R33-E370 IonicContact NH1-OE1 2.99Å; R33-E370 PolarHBondContact NH1-OE1 3.05Å; R33-E370 IonicContact NH1-OE2 3.19Å
34C95.6Very high96.3Very high31 Ų3143.4 Ų43.421%0.20923%0.228CC..EExtended strand (participates in β ladder)trans-96.3121.9-179.1174.60000110.1S12 Y14 N28 D32S12-C34 WeakPolarHBondContact CB-SG 3.44Å; S12-C34 PolarHBondContact OG-SG 3.34Å; Y14-C34 HydrophobicContact CE1-CB 3.72Å; N28-C34 PolarHBondContact ND2-O 2.97Å; D32-C34 PolarHBondContact O-N 2.84Å
35T98Very high96.4Very high3 Ų342.9 Ų42.92%0.01823%0.227CC..EExtended strand (participates in β ladder)trans-106.9111.3171.4-59.70000109.2C13 N28 K124 L125C13-T35 PolarHBondContact N-O 2.72Å; C13-T35 PolarHBondContact O-N 3.22Å; N28-T35 PolarHBondContact ND2-OG1 2.76Å; T35-K124 HydrophobicContact CG2-CG 4.42Å; T35-L125 HydrophobicContact CG2-CD2 3.9Å
36P97.6Very high96.4Very high9 Ų943 Ų436%0.05823%0.227CC..EExtended strand (participates in β ladder)trans-56.7141.3-179.1-27.835.2000113.6Q11 F38 G49 K53Q11-P36 WeakPolarHBondContact O-CA 3.31Å; P36-F38 HydrophobicContact CB-CD2 3.51Å; P36-F38 HydrophobicContact CB-CE2 4.09Å; P36-F38 HydrophobicContact CB-CG 4.3Å; P36-F38 PolarHBondContact O-N 3.43Å; P36-G49 WeakPolarHBondContact O-CA 3.4Å; P36-K53 HydrophobicContact CB-CB 4.05Å; P36-K53 HydrophobicContact CB-CD 3.88Å; P36-K53 HydrophobicContact CB-CG 4.49Å; P36-K53 HydrophobicContact CG-CB 4.1Å; P36-K53 HydrophobicContact CG-CD 3.6Å; P36-K53 HydrophobicContact CG-CG 4.47Å
37S97.2Very high96.4Very high1 Ų143.3 Ų43.31%0.00723%0.23CC..SBendtrans-78.758.9178.7-50.50000112G9 Q11 S12 C13 F67G9-S37 PolarHBondContact O-OG 2.92Å; Q11-S37 VanDerWaalsContact C-OG 3.27Å; Q11-S37 PolarHBondContact O-N 3.35Å; S12-S37 PolarHBondContact N-OG 2.89Å; C13-S37 PolarHBondContact SG-OG 2.98Å; S37-F67 WeakPolarHBondContact O-CE1 3.4Å
38F97.8Very high96.5Very high12 Ų1241.9 Ų41.95%0.05322%0.216CC..EExtended strand (participates in β ladder)trans-126.6138.8-171.9-75.7-115000111.2P36 G49 A52 K53 V56 T63 V64 Q65P36-F38 HydrophobicContact CB-CD2 3.51Å; P36-F38 HydrophobicContact CB-CE2 4.09Å; P36-F38 HydrophobicContact CB-CG 4.3Å; P36-F38 PolarHBondContact O-N 3.43Å; F38-G49 PolarHBondContact O-N 2.72Å; F38-A52 HydrophobicContact CB-CB 3.62Å; F38-A52 WeakPolarHBondContact O-CB 3.42Å; F38-K53 HydrophobicContact CD1-CB 4.25Å; F38-K53 HydrophobicContact CD2-CB 4.42Å; F38-K53 HydrophobicContact CE1-CG 4.35Å; F38-K53 HydrophobicContact CE2-CD 4.49Å; F38-K53 HydrophobicContact CE2-CG 4.45Å; F38-K53 HydrophobicContact CG-CB 4.2Å; F38-K53 HydrophobicContact CZ-CG 4.31Å; F38-V56 HydrophobicContact CD1-CG2 4.45Å; F38-V56 HydrophobicContact CE1-CB 4.23Å; F38-V56 HydrophobicContact CE1-CG2 3.96Å; F38-T63 HydrophobicContact CD1-CG2 3.99Å; F38-V64 WeakPolarHBondContact CA-O 3.23Å; F38-Q65 HydrophobicContact CD1-CB 4.06Å; F38-Q65 HydrophobicContact CE1-CB 3.84Å; F38-Q65 HydrophobicContact CE1-CG 4.29Å; F38-Q65 HydrophobicContact CE2-CB 4.33Å; F38-Q65 HydrophobicContact CG-CB 4.39Å; F38-Q65 HydrophobicContact CZ-CB 3.98Å
39V98.3Very high96.6Very high0 Ų041.4 Ų41.40%021%0.213CC..EExtended strand (participates in β ladder)trans-129.4127.5170.3-175.40000108F41 I48 T63 V64 I117 M120V39-F41 HydrophobicContact CB-CE2 4.37Å; V39-F41 HydrophobicContact CG1-CD2 4.35Å; V39-F41 HydrophobicContact CG1-CE1 4.38Å; V39-F41 HydrophobicContact CG1-CE2 3.61Å; V39-F41 HydrophobicContact CG1-CZ 3.63Å; V39-I48 HydrophobicContact CG2-CG2 4.31Å; V39-T63 CarbonylContact O-C 3.48Å; V39-V64 PolarHBondContact N-O 3.16Å; V39-V64 VanDerWaalsContact N-O 3.1Å; V39-V64 PolarHBondContact O-N 3.2Å; V39-I117 HydrophobicContact CB-CG2 4.4Å; V39-I117 HydrophobicContact CG2-CG2 3.96Å; V39-M120 HydrophobicContact CG1-CB 4.4Å; V39-M120 HydrophobicContact CG1-SD 3.89Å; V39-M120 HydrophobicContact CG2-CB 4.31Å
40S98.1Very high96.7Very high0 Ų037.5 Ų37.50%020%0.198CC..EExtended strand (participates in β ladder)trans-122.1132.6178.5-1640000110.5R46 S47 Q55 N59 N62 T63S40-R46 CarbonylContact O-C 3.56Å; S40-R46 VanDerWaalsContact O-CA 3.26Å; S40-R46 WeakPolarHBondContact O-CA 3.31Å; S40-R46 WeakPolarHBondContact O-CB 3.5Å; S40-S47 PolarHBondContact N-O 2.93Å; S40-S47 PolarHBondContact O-N 2.99Å; S40-Q55 PolarHBondContact OG-OE1 2.99Å; S40-N59 PolarHBondContact OG-ND2 2.89Å; S40-N62 WeakPolarHBondContact CA-O 3.37Å; S40-T63 PolarHBondContact OG-OG1 3.05Å
41F98.3Very high96.8Very high1 Ų132.2 Ų32.20%0.00418%0.181CC..EExtended strand (participates in β ladder)trans-104.5126.3-178-62.8-91.9000110.7V39 R46 N59 N62 V64 V103 L104 Y105 F112 I117 M120V39-F41 HydrophobicContact CB-CE2 4.37Å; V39-F41 HydrophobicContact CG1-CD2 4.35Å; V39-F41 HydrophobicContact CG1-CE1 4.38Å; V39-F41 HydrophobicContact CG1-CE2 3.61Å; V39-F41 HydrophobicContact CG1-CZ 3.63Å; F41-R46 HydrophobicContact CD1-CB 4.24Å; F41-N59 PolarHBondContact O-ND2 2.84Å; F41-N62 HydrophobicContact CB-CB 4.29Å; F41-N62 PolarHBondContact N-O 3.26Å; F41-N62 WeakPolarHBondContact O-CB 3.41Å; F41-V64 HydrophobicContact CD2-CG2 4.32Å; F41-V64 HydrophobicContact CE2-CG2 3.96Å; F41-V103 HydrophobicContact CB-CB 4.39Å; F41-V103 HydrophobicContact CB-CG2 4.26Å; F41-V103 HydrophobicContact CD1-CG2 4.24Å; F41-V103 HydrophobicContact CD2-CB 3.99Å; F41-V103 HydrophobicContact CD2-CG1 3.85Å; F41-V103 HydrophobicContact CD2-CG2 3.7Å; F41-V103 HydrophobicContact CE2-CG1 4.23Å; F41-V103 HydrophobicContact CE2-CG2 4.06Å; F41-V103 HydrophobicContact CG-CB 4.28Å; F41-V103 HydrophobicContact CG-CG2 3.8Å; F41-V103 HydrophobicContact CZ-CG2 4.46Å; F41-L104 WeakPolarHBondContact CB-O 3.35Å; F41-Y105 HydrophobicContact CB-CD2 4.12Å; F41-Y105 HydrophobicContact CB-CG 4.46Å; F41-Y105 AromaticContact CD1-CD2 3.72Å; F41-Y105 HydrophobicContact CD1-CD2 3.72Å; F41-Y105 HydrophobicContact CD1-CE2 4.39Å; F41-Y105 AromaticContact CD1-CG 3.81Å; F41-Y105 HydrophobicContact CD1-CG 3.81Å; F41-Y105 HydrophobicContact CG-CD2 4.43Å; F41-F112 AromaticContact CD1-CE2 3.93Å; F41-F112 HydrophobicContact CD1-CE2 3.93Å; F41-F112 HydrophobicContact CD1-CZ 4.44Å; F41-F112 AromaticContact CE1-CD2 3.95Å; F41-F112 HydrophobicContact CE1-CD2 3.95Å; F41-F112 AromaticContact CE1-CE2 3.41Å; F41-F112 HydrophobicContact CE1-CE2 3.41Å; F41-F112 VanDerWaalsContact CE1-CE2 3.41Å; F41-F112 AromaticContact CE1-CZ 3.85Å; F41-F112 HydrophobicContact CE1-CZ 3.85Å; F41-F112 AromaticContact CZ-CD2 3.86Å; F41-F112 HydrophobicContact CZ-CD2 3.86Å; F41-F112 AromaticContact CZ-CE2 3.83Å; F41-F112 HydrophobicContact CZ-CE2 3.83Å; F41-I117 HydrophobicContact CE2-CD1 3.8Å; F41-I117 HydrophobicContact CZ-CD1 3.54Å; F41-M120 HydrophobicContact CE1-CE 3.86Å; F41-M120 HydrophobicContact CE1-SD 3.69Å; F41-M120 HydrophobicContact CZ-CE 3.79Å; F41-M120 HydrophobicContact CZ-SD 3.55Å; F41-M120 VanDerWaalsContact CZ-SD 3.55Å
42G95.8Very high96.8Very high14 Ų1427.3 Ų27.314%0.14415%0.146CC..  trans-113.9-176.9179.500000113.4R44 N45 M106G42-R44 PolarHBondContact O-N 2.9Å; G42-N45 WeakPolarHBondContact CA-O 3.47Å; G42-N45 PolarHBondContact N-O 2.95Å; G42-M106 PolarHBondContact O-N 2.98Å
43P94.9Very high96.8Very high81 Ų8126.2 Ų26.253%0.52614%0.137SC..SBendtrans-74.1-7.9179.830.6-35.8000114M106 E107P43-M106 WeakPolarHBondContact O-CA 3.4Å; P43-E107 HydrophobicContact CB-CG 4.02Å
44R92.7Very high96.8Very high82 Ų8224.6 Ų24.631%0.30915%0.145SC..SBendtrans-133.7-42.7-173.5-66.2-178.3174.2-126.4-14.3114.1G42 Q606 E610 D664G42-R44 PolarHBondContact O-N 2.9Å; R44-Q606 VanDerWaalsContact O-CG 3.25Å; R44-Q606 WeakPolarHBondContact O-CG 3.36Å; R44-Q606 PolarHBondContact O-NE2 2.93Å; R44-E610 HydrophobicContact CB-CG 4.05Å; R44-E610 IonicContact NH1-OE2 2.7Å; R44-D664 IonicContact CZ-OD1 2.8Å; R44-D664 IonicContact CZ-OD2 2.67Å; R44-D664 IonicContact NH1-OD1 3.58Å; R44-D664 PolarHBondContact NH1-OD1 2.94Å; R44-D664 IonicContact NH1-OD2 3.79Å; R44-D664 IonicContact NH2-OD1 3.98Å; R44-D664 PolarHBondContact NH2-OD1 3.15Å; R44-D664 IonicContact NH2-OD2 2.81Å; R44-D664 PolarHBondContact NH2-OD2 2.79Å
45N95.8Very high96.7Very high48 Ų4825.8 Ų25.826%0.25715%0.147SC..  trans-142.5172.6-175.869.2-61.2000108.9G42 D607 E610G42-N45 WeakPolarHBondContact CA-O 3.47Å; G42-N45 PolarHBondContact N-O 2.95Å; N45-D607 WeakPolarHBondContact CB-OD1 3.4Å; N45-E610 HydrophobicContact CB-CB 4.12Å; N45-E610 HydrophobicContact CB-CG 4.09Å
46R97.3Very high96.5Very high8 Ų825.9 Ų25.93%0.0315%0.147CC..EExtended strand (participates in β ladder)trans-101.3152.5164.550.1175.1-173.3178.68.7109.5S40 F41 Y105 M120 E600 D607S40-R46 CarbonylContact O-C 3.56Å; S40-R46 VanDerWaalsContact O-CA 3.26Å; S40-R46 WeakPolarHBondContact O-CA 3.31Å; S40-R46 WeakPolarHBondContact O-CB 3.5Å; F41-R46 HydrophobicContact CD1-CB 4.24Å; R46-Y105 HydrophobicContact CB-CE2 4.43Å; R46-M120 PolarHBondContact NH1-SD 2.83Å; R46-E600 IonicContact CZ-OE1 2.68Å; R46-E600 IonicContact CZ-OE2 2.68Å; R46-E600 VanDerWaalsContact NH1-CD 3.31Å; R46-E600 IonicContact NH1-OE1 3.7Å; R46-E600 PolarHBondContact NH1-OE1 2.82Å; R46-E600 IonicContact NH1-OE2 2.74Å; R46-E600 PolarHBondContact NH1-OE2 3.48Å; R46-E600 IonicContact NH2-OE1 3.54Å; R46-E600 PolarHBondContact NH2-OE1 3.19Å; R46-E600 IonicContact NH2-OE2 3.01Å; R46-D607 WeakPolarHBondContact CG-OD1 3.38Å; R46-D607 VanDerWaalsContact CG-OD2 3.25Å; R46-D607 WeakPolarHBondContact CG-OD2 3.07Å; R46-D607 IonicContact CZ-OD2 3.72Å; R46-D607 PolarHBondContact N-OD1 2.92Å; R46-D607 IonicContact NE-OD2 2.8Å; R46-D607 PolarHBondContact NE-OD2 3.44Å; R46-D607 IonicContact NH2-OD2 2.75Å; R46-D607 PolarHBondContact NH2-OD2 2.95Å
47S97.6Very high96.3Very high17 Ų1726.9 Ų26.912%0.11915%0.153CC..EExtended strand (participates in β ladder)trans-109144167.9-62.60000108.3S40 A52 Q55S40-S47 PolarHBondContact N-O 2.93Å; S40-S47 PolarHBondContact O-N 2.99Å; S47-A52 WeakPolarHBondContact O-CB 3.47Å; S47-Q55 PolarHBondContact OG-NE2 2.75Å; S47-Q55 PolarHBondContact OG-OE1 2.97Å
48I98.3Very high96.1Very high16 Ų1631.5 Ų31.58%0.08218%0.181CC..EExtended strand (participates in β ladder)trans-139.3141.6-175.2-45.7174.9000109V39 M120 L121 K124V39-I48 HydrophobicContact CG2-CG2 4.31Å; I48-M120 HydrophobicContact CD1-CB 3.99Å; I48-M120 WeakPolarHBondContact CD1-O 3.34Å; I48-L121 HydrophobicContact CG2-CD1 4.22Å; I48-K124 HydrophobicContact CB-CB 4Å; I48-K124 HydrophobicContact CB-CG 4.04Å; I48-K124 HydrophobicContact CD1-CB 4.46Å; I48-K124 HydrophobicContact CG2-CB 3.5Å; I48-K124 HydrophobicContact CG2-CG 3.82Å
49G97.7Very high96Very high0 Ų032.7 Ų32.70%019%0.188CC..THydrogen-bonded Turntrans78.6-133.3-179.900000112.7P36 F38 A51 A52 K53P36-G49 WeakPolarHBondContact O-CA 3.4Å; F38-G49 PolarHBondContact O-N 2.72Å; G49-A51 VanDerWaalsContact C-N 3.33Å; G49-A51 PolarHBondContact O-N 2.84Å; G49-A52 WeakPolarHBondContact O-CB 3.5Å; G49-A52 PolarHBondContact O-N 2.73Å; G49-A52 VanDerWaalsContact O-N 3.13Å; G49-K53 PolarHBondContact O-N 2.84Å
50A97.1Very high95.8Very high18 Ų1833.3 Ų33.315%0.14919%0.193CC..Hα-helixtrans-62.6-37.6-177.700000112.7Y30 A52 K53 S54Y30-A50 HydrophobicContact CD2-CB 3.49Å; Y30-A50 VanDerWaalsContact CD2-CB 3.49Å; Y30-A50 HydrophobicContact CE2-CB 3.66Å; Y30-A50 HydrophobicContact CG-CB 4.15Å; A50-A52 VanDerWaalsContact C-N 3.29Å; A50-A52 PolarHBondContact O-N 2.74Å; A50-K53 PolarHBondContact O-N 2.81Å; A50-K53 VanDerWaalsContact O-N 3.12Å; A50-S54 PolarHBondContact O-N 2.9Å
51A96Very high95.6Very high18 Ų1839.9 Ų39.915%0.14922%0.221CC..Hα-helixtrans-62.1-32.8174.100000113.3G49 S54 Q55G49-A51 VanDerWaalsContact C-N 3.33Å; G49-A51 PolarHBondContact O-N 2.84Å; A51-S54 PolarHBondContact O-OG 2.84Å; A51-S54 VanDerWaalsContact O-OG 3.06Å; A51-Q55 VanDerWaalsContact O-CD 3.3Å; A51-Q55 WeakPolarHBondContact O-CG 3.44Å; A51-Q55 PolarHBondContact O-NE2 3.39Å
52A97.3Very high95.5Very high0 Ų041.1 Ų41.10%023%0.228CC..Hα-helixtrans-74.8-37.9172.600000111.8F38 S47 G49 A50 Q55 V56 T63F38-A52 HydrophobicContact CB-CB 3.62Å; F38-A52 WeakPolarHBondContact O-CB 3.42Å; S47-A52 WeakPolarHBondContact O-CB 3.47Å; G49-A52 WeakPolarHBondContact O-CB 3.5Å; G49-A52 PolarHBondContact O-N 2.73Å; G49-A52 VanDerWaalsContact O-N 3.13Å; A50-A52 VanDerWaalsContact C-N 3.29Å; A50-A52 PolarHBondContact O-N 2.74Å; A52-Q55 PolarHBondContact O-N 2.83Å; A52-V56 PolarHBondContact O-N 2.79Å; A52-T63 WeakPolarHBondContact O-CG2 3.34Å
53K96.1Very high95.5Very high70 Ų7040.6 Ų40.630%0.30422%0.222SC..Hα-helixtrans-65.4-38.1179.2-174.7176.9178.4177.30112.5P36 F38 G49 A50 Q55 V56P36-K53 HydrophobicContact CB-CB 4.05Å; P36-K53 HydrophobicContact CB-CD 3.88Å; P36-K53 HydrophobicContact CB-CG 4.49Å; P36-K53 HydrophobicContact CG-CB 4.1Å; P36-K53 HydrophobicContact CG-CD 3.6Å; P36-K53 HydrophobicContact CG-CG 4.47Å; F38-K53 HydrophobicContact CD1-CB 4.25Å; F38-K53 HydrophobicContact CD2-CB 4.42Å; F38-K53 HydrophobicContact CE1-CG 4.35Å; F38-K53 HydrophobicContact CE2-CD 4.49Å; F38-K53 HydrophobicContact CE2-CG 4.45Å; F38-K53 HydrophobicContact CG-CB 4.2Å; F38-K53 HydrophobicContact CZ-CG 4.31Å; G49-K53 PolarHBondContact O-N 2.84Å; A50-K53 PolarHBondContact O-N 2.81Å; A50-K53 VanDerWaalsContact O-N 3.12Å; K53-Q55 VanDerWaalsContact C-N 3.28Å; K53-Q55 PolarHBondContact O-N 3.08Å; K53-V56 WeakPolarHBondContact O-CG1 3.37Å; K53-V56 PolarHBondContact O-N 3.02Å
54S95Very high95.6Very high88 Ų8836.7 Ų36.762%0.61520%0.197SC*.Hα-helixtrans-65.1-32.7175.759.20000112.5A50 A51 V56A50-S54 PolarHBondContact O-N 2.9Å; A51-S54 PolarHBondContact O-OG 2.84Å; A51-S54 VanDerWaalsContact O-OG 3.06Å; S54-V56 PolarHBondContact O-N 2.92Å
55Q94.3Very high95.6Very high56 Ų5636.2 Ų36.226%0.26220%0.198SC..Hα-helixtrans-80.3-8.2179.6-65.6168.917.500114.3S40 S47 A51 A52 K53 V57 T58 N59S40-Q55 PolarHBondContact OG-OE1 2.99Å; S47-Q55 PolarHBondContact OG-NE2 2.75Å; S47-Q55 PolarHBondContact OG-OE1 2.97Å; A51-Q55 VanDerWaalsContact O-CD 3.3Å; A51-Q55 WeakPolarHBondContact O-CG 3.44Å; A51-Q55 PolarHBondContact O-NE2 3.39Å; A52-Q55 PolarHBondContact O-N 2.83Å; K53-Q55 VanDerWaalsContact C-N 3.28Å; K53-Q55 PolarHBondContact O-N 3.08Å; Q55-V57 PolarHBondContact O-N 2.96Å; Q55-V57 VanDerWaalsContact O-N 3.09Å; Q55-T58 PolarHBondContact O-N 2.84Å; Q55-T58 VanDerWaalsContact O-N 3.1Å; Q55-T58 PolarHBondContact O-OG1 2.84Å; Q55-T58 VanDerWaalsContact O-OG1 3.08Å; Q55-N59 HydrophobicContact CB-CB 4.38Å; Q55-N59 PolarHBondContact O-N 2.86Å
56V94.3Very high95.5Very high4 Ų435 Ų352%0.02420%0.197CC..THydrogen-bonded Turntrans-61.5-25.4-171.7760000114.5F38 A52 K53 S54 C60 T63 V264 Q268F38-V56 HydrophobicContact CD1-CG2 4.45Å; F38-V56 HydrophobicContact CE1-CB 4.23Å; F38-V56 HydrophobicContact CE1-CG2 3.96Å; A52-V56 PolarHBondContact O-N 2.79Å; K53-V56 WeakPolarHBondContact O-CG1 3.37Å; K53-V56 PolarHBondContact O-N 3.02Å; S54-V56 PolarHBondContact O-N 2.92Å; V56-C60 WeakPolarHBondContact O-CA 3.25Å; V56-C60 WeakPolarHBondContact O-CB 3.37Å; V56-T63 HydrophobicContact CB-CG2 3.87Å; V56-T63 HydrophobicContact CG2-CG2 3.77Å; V56-V264 HydrophobicContact CB-CG1 4.46Å; V56-V264 HydrophobicContact CG1-CG1 3.86Å; V56-V264 HydrophobicContact CG2-CG1 3.96Å; V56-Q268 VanDerWaalsContact CG1-NE2 3.27Å
57V92.9Very high95.3Very high30 Ų3034.7 Ų34.718%0.18220%0.196CC..THydrogen-bonded Turntrans-86.9-25.9179177.50000112.5Q55 R261 V264 R265Q55-V57 PolarHBondContact O-N 2.96Å; Q55-V57 VanDerWaalsContact O-N 3.09Å; V57-R261 WeakPolarHBondContact O-CG 3.49Å; V57-R261 PolarHBondContact O-NE 3.26Å; V57-V264 HydrophobicContact CG2-CG1 3.98Å; V57-R265 HydrophobicContact CG1-CG 3.7Å; V57-R265 HydrophobicContact CG2-CG 3.98Å
58T93.8Very high95.1Very high98 Ų9834 Ų3460%0.60119%0.191SC*.THydrogen-bonded Turntrans-92.4-49.7178.9470000111.3Q55Q55-T58 PolarHBondContact O-N 2.84Å; Q55-T58 VanDerWaalsContact O-N 3.1Å; Q55-T58 PolarHBondContact O-OG1 2.84Å; Q55-T58 VanDerWaalsContact O-OG1 3.08Å
59N95.4Very high94.8Very high37 Ų3736.2 Ų36.220%0.19820%0.198CC..SBendtrans-101.140-178.1-165.822.3000112.5S40 F41 Q55 K61 N62 T63S40-N59 PolarHBondContact OG-ND2 2.89Å; F41-N59 PolarHBondContact O-ND2 2.84Å; Q55-N59 HydrophobicContact CB-CB 4.38Å; Q55-N59 PolarHBondContact O-N 2.86Å; N59-K61 VanDerWaalsContact C-N 3.33Å; N59-K61 PolarHBondContact O-N 2.9Å; N59-N62 PolarHBondContact O-N 3.12Å; N59-N62 VanDerWaalsContact O-N 3.12Å; N59-N62 WeakPolarHBondContact OD1-CB 3.34Å; N59-N62 PolarHBondContact OD1-ND2 3.29Å; N59-T63 WeakPolarHBondContact O-CB 3.5Å; N59-T63 PolarHBondContact O-N 3.15Å; N59-T63 VanDerWaalsContact O-N 3.12Å; N59-T63 PolarHBondContact O-OG1 3.03Å
60C92.9Very high94.7Very high14 Ų1436.3 Ų36.310%0.09520%0.199CC..G310 helixtrans-58.5-37.1-164.964.70000114.8V56 T63 V88V56-C60 WeakPolarHBondContact O-CA 3.25Å; V56-C60 WeakPolarHBondContact O-CB 3.37Å; C60-T63 PolarHBondContact O-N 2.88Å; C60-V88 HydrophobicContact CB-CG1 3.82Å
61K93.9Very high94.6Very high137 Ų13735.5 Ų35.560%0.59619%0.191SC*.G310 helixtrans-69.5-29.8179.7-70.1-168.8173.8-167.60114.1N59 Y89N59-K61 VanDerWaalsContact C-N 3.33Å; N59-K61 PolarHBondContact O-N 2.9Å; K61-Y89 WeakPolarHBondContact O-CA 3.45Å; K61-Y89 WeakPolarHBondContact O-CB 3.36Å
62N96.8Very high94.5Very high28 Ų2834.8 Ų34.815%0.1519%0.186CC..G310 helixtrans-104.810.4-178.7-47.7-55.7000111.9S40 F41 N59 V103 L104S40-N62 WeakPolarHBondContact CA-O 3.37Å; F41-N62 HydrophobicContact CB-CB 4.29Å; F41-N62 PolarHBondContact N-O 3.26Å; F41-N62 WeakPolarHBondContact O-CB 3.41Å; N59-N62 PolarHBondContact O-N 3.12Å; N59-N62 VanDerWaalsContact O-N 3.12Å; N59-N62 WeakPolarHBondContact OD1-CB 3.34Å; N59-N62 PolarHBondContact OD1-ND2 3.29Å; N62-V103 HydrophobicContact CB-CB 4.48Å; N62-L104 WeakPolarHBondContact OD1-CB 3.45Å; N62-L104 PolarHBondContact OD1-N 3.1Å
63T96.8Very high94.4Very high2 Ų235.6 Ų35.61%0.01219%0.189CC..EExtended strand (participates in β ladder)trans-106.9105.7177.4-54.10000110.3F38 V39 S40 A52 V56 N59 C60F38-T63 HydrophobicContact CD1-CG2 3.99Å; V39-T63 CarbonylContact O-C 3.48Å; S40-T63 PolarHBondContact OG-OG1 3.05Å; A52-T63 WeakPolarHBondContact O-CG2 3.34Å; V56-T63 HydrophobicContact CB-CG2 3.87Å; V56-T63 HydrophobicContact CG2-CG2 3.77Å; N59-T63 WeakPolarHBondContact O-CB 3.5Å; N59-T63 PolarHBondContact O-N 3.15Å; N59-T63 VanDerWaalsContact O-N 3.12Å; N59-T63 PolarHBondContact O-OG1 3.03Å; C60-T63 PolarHBondContact O-N 2.88Å
64V96Very high94.3Very high0 Ų032.5 Ų32.50%018%0.177CC..EExtended strand (participates in β ladder)trans-90.9128.7-173-165.70000110.1F38 V39 F41 F67 Y89 I101 V103 I117F38-V64 WeakPolarHBondContact CA-O 3.23Å; V39-V64 PolarHBondContact N-O 3.16Å; V39-V64 VanDerWaalsContact N-O 3.1Å; V39-V64 PolarHBondContact O-N 3.2Å; F41-V64 HydrophobicContact CD2-CG2 4.32Å; F41-V64 HydrophobicContact CE2-CG2 3.96Å; V64-F67 HydrophobicContact CB-CD1 4.49Å; V64-F67 HydrophobicContact CG1-CB 3.99Å; V64-F67 HydrophobicContact CG1-CD1 3.78Å; V64-F67 HydrophobicContact CG1-CG 4.2Å; V64-Y89 HydrophobicContact CB-CD1 4.5Å; V64-Y89 HydrophobicContact CB-CE1 4.47Å; V64-Y89 HydrophobicContact CG1-CD1 4.3Å; V64-Y89 HydrophobicContact CG1-CD2 4.27Å; V64-Y89 HydrophobicContact CG1-CE1 3.93Å; V64-Y89 HydrophobicContact CG1-CE2 3.88Å; V64-Y89 HydrophobicContact CG1-CG 4.46Å; V64-I101 HydrophobicContact CG1-CD1 4.09Å; V64-I101 HydrophobicContact CG1-CG2 3.85Å; V64-I101 HydrophobicContact CG2-CG2 3.75Å; V64-V103 HydrophobicContact CG2-CG1 3.89Å; V64-I117 HydrophobicContact CG1-CG2 4.33Å
65Q93.7Very high94.3Very high71 Ų7129.8 Ų29.833%0.33215%0.154SC..EExtended strand (participates in β ladder)trans-142.8154.217756.6167.6-14.100110.4F38 F67 Y89F38-Q65 HydrophobicContact CD1-CB 4.06Å; F38-Q65 HydrophobicContact CE1-CB 3.84Å; F38-Q65 HydrophobicContact CE1-CG 4.29Å; F38-Q65 HydrophobicContact CE2-CB 4.33Å; F38-Q65 HydrophobicContact CG-CB 4.39Å; F38-Q65 HydrophobicContact CZ-CB 3.98Å; Q65-F67 PolarHBondContact O-N 3.3Å; Q65-F67 VanDerWaalsContact O-N 3.11Å; Q65-Y89 WeakPolarHBondContact O-CE1 3.25Å; Q65-Y89 PolarHBondContact O-OH 2.8Å
66G91.8Very high94.4Very high23 Ų2331.2 Ų31.224%0.23717%0.17CC..SBendtrans69.72.417700000116K68 R69G66-K68 PolarHBondContact O-N 2.8Å; G66-K68 VanDerWaalsContact O-N 3.12Å; G66-R69 PolarHBondContact O-N 2.88Å
67F94.4Very high94.4Very high2 Ų231.2 Ų31.21%0.00917%0.17CC..G310 helixtrans-57.3-25.3-177.154.8-91.4000114.4S37 V64 Q65 R69 F70 I101 V114 I117 T118 L121S37-F67 WeakPolarHBondContact O-CE1 3.4Å; V64-F67 HydrophobicContact CB-CD1 4.49Å; V64-F67 HydrophobicContact CG1-CB 3.99Å; V64-F67 HydrophobicContact CG1-CD1 3.78Å; V64-F67 HydrophobicContact CG1-CG 4.2Å; Q65-F67 PolarHBondContact O-N 3.3Å; Q65-F67 VanDerWaalsContact O-N 3.11Å; F67-R69 PolarHBondContact O-N 2.92Å; F67-F70 WeakPolarHBondContact O-CB 3.49Å; F67-F70 WeakPolarHBondContact O-CD2 3.43Å; F67-F70 PolarHBondContact O-N 2.91Å; F67-I101 HydrophobicContact CB-CD1 3.67Å; F67-V114 HydrophobicContact CD2-CG1 4.46Å; F67-I117 HydrophobicContact CD1-CG2 3.79Å; F67-I117 HydrophobicContact CD2-CB 4.24Å; F67-I117 HydrophobicContact CD2-CG2 3.63Å; F67-I117 HydrophobicContact CE1-CG2 3.8Å; F67-I117 HydrophobicContact CE2-CB 4.42Å; F67-I117 HydrophobicContact CE2-CG2 3.66Å; F67-I117 HydrophobicContact CG-CG2 3.7Å; F67-I117 HydrophobicContact CZ-CG2 3.73Å; F67-T118 WeakPolarHBondContact CE2-OG1 3.17Å; F67-L121 HydrophobicContact CZ-CD2 3.86Å
68K93.3Very high94.4Very high2 Ų234.1 Ų34.11%0.00919%0.19CC..G310 helixtrans-50.2-26.5177-79.9-155.276.5-158.70114.4L8 F10 G66 F70 H71 Y148L8-K68 HydrophobicContact CG-CD 4.16Å; L8-K68 WeakPolarHBondContact O-CD 3.22Å; L8-K68 VanDerWaalsContact O-CE 3.27Å; L8-K68 WeakPolarHBondContact O-CE 3.37Å; L8-K68 PolarHBondContact O-NZ 3.36Å; F10-K68 HydrophobicContact CD1-CB 3.68Å; F10-K68 HydrophobicContact CE1-CB 3.67Å; G66-K68 PolarHBondContact O-N 2.8Å; G66-K68 VanDerWaalsContact O-N 3.12Å; K68-F70 PolarHBondContact O-N 3.42Å; K68-H71 PolarHBondContact O-CD2 2.83Å; K68-H71 VanDerWaalsContact O-CD2 3.31Å; K68-Y148 WeakPolarHBondContact CE-OH 3.44Å; K68-Y148 PolarHBondContact O-OH 3.39Å
69R91.4Very high94.2Very high63 Ų6331.3 Ų31.324%0.23817%0.17CC..G310 helixtrans-760.3179.484.5-164.9-44.1-1645.6114.2F10 G66 F67 R73 D230F10-R69 HydrophobicContact CE1-CB 3.96Å; G66-R69 PolarHBondContact O-N 2.88Å; F67-R69 PolarHBondContact O-N 2.92Å; R69-R73 WeakPolarHBondContact O-CD 3.3Å; R69-D230 IonicContact NH2-OD1 3.28Å
70F95.3Very high94.2Very high2 Ų229.6 Ų29.61%0.00916%0.161CC..G310 helixtrans-110.22.1179-48-44000113.4F67 K68 G72 R73 V80 A83 L87 L91 T99 V114F67-F70 WeakPolarHBondContact O-CB 3.49Å; F67-F70 WeakPolarHBondContact O-CD2 3.43Å; F67-F70 PolarHBondContact O-N 2.91Å; K68-F70 PolarHBondContact O-N 3.42Å; F70-G72 PolarHBondContact O-N 3.49Å; F70-R73 PolarHBondContact O-N 2.79Å; F70-V80 HydrophobicContact CD1-CG2 3.81Å; F70-V80 HydrophobicContact CE1-CG2 4.47Å; F70-A83 HydrophobicContact CE1-CB 3.66Å; F70-A83 HydrophobicContact CZ-CB 3.69Å; F70-L87 HydrophobicContact CE2-CD1 4.05Å; F70-L87 HydrophobicContact CZ-CD1 3.97Å; F70-L91 HydrophobicContact CD2-CD2 4.42Å; F70-L91 HydrophobicContact CE2-CD1 4.19Å; F70-L91 HydrophobicContact CE2-CD2 4.24Å; F70-L91 HydrophobicContact CZ-CD1 4.16Å; F70-T99 HydrophobicContact CB-CG2 4.11Å; F70-T99 HydrophobicContact CG-CG2 4.37Å; F70-V114 HydrophobicContact CB-CG1 4.46Å; F70-V114 HydrophobicContact CB-CG2 3.73Å
71H95.8Very high94.3Very high0 Ų033 Ų330%018%0.176CC..THydrogen-bonded Turntrans-51.4131.6176-90.9-63.6000111.1K68 R73 T118 E152 S155K68-H71 PolarHBondContact O-CD2 2.83Å; K68-H71 VanDerWaalsContact O-CD2 3.31Å; H71-R73 PolarHBondContact O-N 2.67Å; H71-T118 PolarHBondContact CE1-OG1 3.23Å; H71-T118 PolarHBondContact NE2-OG1 2.9Å; H71-E152 HydrophobicContact CB-CG 4.37Å; H71-E152 WeakPolarHBondContact O-CG 3.36Å; H71-S155 PolarHBondContact ND1-OG 2.88Å
72G93.8Very high94.2Very high3 Ų329.4 Ų29.43%0.03117%0.172CC..THydrogen-bonded Turntrans58.320.8176.500000115.5F70 S155 Y454F70-G72 PolarHBondContact O-N 3.49Å; G72-S155 VanDerWaalsContact N-CB 3.33Å; G72-S155 PolarHBondContact N-OG 2.94Å; G72-S155 VanDerWaalsContact N-OG 3.08Å; G72-Y454 WeakPolarHBondContact O-CE2 3.34Å; G72-Y454 PolarHBondContact O-OH 2.8Å
73R94.4Very high93.8Very high17 Ų1728.7 Ų28.76%0.06417%0.17CC..  trans-110.6137.6-176.9-73172.1-175.2-97.33.6112.9R69 F70 H71 D77 V80 T99 E152 N453 Y454R69-R73 WeakPolarHBondContact O-CD 3.3Å; F70-R73 PolarHBondContact O-N 2.79Å; H71-R73 PolarHBondContact O-N 2.67Å; R73-D77 HydrophobicContact CB-CB 4.38Å; R73-D77 WeakPolarHBondContact CD-OD2 3.44Å; R73-D77 WeakPolarHBondContact CG-OD2 3.46Å; R73-D77 IonicContact CZ-OD2 2.7Å; R73-D77 IonicContact NE-OD2 3.19Å; R73-D77 IonicContact NH1-OD1 2.77Å; R73-D77 IonicContact NH1-OD2 3.61Å; R73-D77 PolarHBondContact NH1-OD2 3.29Å; R73-V80 HydrophobicContact CB-CG2 4.03Å; R73-T99 WeakPolarHBondContact O-CB 3.15Å; R73-T99 PolarHBondContact O-N 2.98Å; R73-T99 PolarHBondContact O-OG1 3.28Å; R73-E152 IonicContact CZ-OE1 3.15Å; R73-E152 VanDerWaalsContact CZ-OE1 3.28Å; R73-E152 IonicContact NE-OE1 2.75Å; R73-E152 PolarHBondContact NE-OE1 3.07Å; R73-E152 IonicContact NH2-OE1 3.64Å; R73-E152 PolarHBondContact NH2-OE1 3.38Å; R73-N453 PolarHBondContact NH1-O 2.78Å; R73-N453 VanDerWaalsContact NH1-O 3.1Å; R73-N453 PolarHBondContact NH2-O 2.93Å; R73-Y454 HydrophobicContact CG-CD2 4.2Å; R73-Y454 HydrophobicContact CG-CE2 3.67Å
74A94.6Very high93.5Very high6 Ų632.5 Ų32.55%0.0519%0.186CC..BIsolated β-bridgetrans-59.3145.8170.800000110.7S76 D77 T99 W586A74-S76 PolarHBondContact O-N 3.04Å; A74-S76 VanDerWaalsContact O-N 3.16Å; A74-D77 VanDerWaalsContact O-CB 3.23Å; A74-D77 WeakPolarHBondContact O-CB 3.32Å; A74-D77 PolarHBondContact O-N 2.84Å; A74-T99 PolarHBondContact O-OG1 3.31Å; A74-W586 HydrophobicContact CB-CH2 3.58Å; A74-W586 HydrophobicContact CB-CZ2 3.49Å; A74-W586 VanDerWaalsContact CB-CZ2 3.49Å; A74-W586 HydrophobicContact CB-CZ3 4.36Å
75F95.9Very high92.9Very high30 Ų3037.3 Ų37.313%0.13222%0.22CC..THydrogen-bonded Turntrans-57.7-31.6171179-106.1000111.7D77 V80 Q81 L91 A92 Q93 G97 T99F75-D77 VanDerWaalsContact C-N 3.28Å; F75-D77 PolarHBondContact O-N 2.82Å; F75-V80 HydrophobicContact CD2-CG1 4.38Å; F75-Q81 PolarHBondContact O-NE2 2.95Å; F75-L91 HydrophobicContact CE2-CB 3.98Å; F75-A92 VanDerWaalsContact CD2-C 3.46Å; F75-A92 WeakPolarHBondContact CD2-O 3.23Å; F75-Q93 HydrophobicContact CB-CB 3.93Å; F75-Q93 HydrophobicContact CB-CG 3.8Å; F75-Q93 HydrophobicContact CD1-CB 3.66Å; F75-Q93 HydrophobicContact CD1-CG 4.08Å; F75-Q93 HydrophobicContact CD2-CB 4.44Å; F75-Q93 HydrophobicContact CE1-CB 4.26Å; F75-Q93 HydrophobicContact CG-CB 3.75Å; F75-Q93 HydrophobicContact CG-CG 4.14Å; F75-G97 PolarHBondContact N-O 3.42Å; F75-T99 PolarHBondContact N-OG1 3.49Å
76S95.3Very high92.4Very high87 Ų8738.1 Ų38.161%0.60823%0.226SC*.THydrogen-bonded Turntrans-80.86.9177.566.30000115.1A74A74-S76 PolarHBondContact O-N 3.04Å; A74-S76 VanDerWaalsContact O-N 3.16Å
77D94.3Very high92.2Very high4 Ų439.2 Ų39.22%0.02123%0.227CC..  trans-64.8129.7173.5-177.5-30000109.5R73 A74 F75 I79 V80 Q81 P455R73-D77 HydrophobicContact CB-CB 4.38Å; R73-D77 WeakPolarHBondContact CD-OD2 3.44Å; R73-D77 WeakPolarHBondContact CG-OD2 3.46Å; R73-D77 IonicContact CZ-OD2 2.7Å; R73-D77 IonicContact NE-OD2 3.19Å; R73-D77 IonicContact NH1-OD1 2.77Å; R73-D77 IonicContact NH1-OD2 3.61Å; R73-D77 PolarHBondContact NH1-OD2 3.29Å; A74-D77 VanDerWaalsContact O-CB 3.23Å; A74-D77 WeakPolarHBondContact O-CB 3.32Å; A74-D77 PolarHBondContact O-N 2.84Å; F75-D77 VanDerWaalsContact C-N 3.28Å; F75-D77 PolarHBondContact O-N 2.82Å; D77-I79 PolarHBondContact O-N 2.74Å; D77-I79 VanDerWaalsContact O-N 3.12Å; D77-I79 WeakPolarHBondContact OD1-CB 3.42Å; D77-I79 PolarHBondContact OD1-N 2.85Å; D77-V80 HydrophobicContact CB-CB 4.17Å; D77-V80 HydrophobicContact CB-CG2 3.82Å; D77-V80 WeakPolarHBondContact O-CB 3.49Å; D77-V80 PolarHBondContact O-N 3.19Å; D77-Q81 PolarHBondContact O-N 3Å; D77-P455 HydrophobicContact CB-CG 4.23Å; D77-P455 VanDerWaalsContact OD2-CD 3.31Å; D77-P455 WeakPolarHBondContact OD2-CD 3.26Å
78P92.8Very high92Very high91 Ų9140.7 Ų40.759%0.59124%0.236SC*.Hα-helixtrans-50.9-33.1176-2936.3000114.7A82P78-A82 WeakPolarHBondContact O-CB 3.34Å; P78-A82 PolarHBondContact O-N 2.82Å
79I90.6Very high92Very high39 Ų3941 Ų4120%0.224%0.237CC..Hα-helixtrans-70.8-38.6177.6-70.3162.4000111.2D77 A83 N453D77-I79 PolarHBondContact O-N 2.74Å; D77-I79 VanDerWaalsContact O-N 3.12Å; D77-I79 WeakPolarHBondContact OD1-CB 3.42Å; D77-I79 PolarHBondContact OD1-N 2.85Å; I79-A83 VanDerWaalsContact O-CB 3.31Å; I79-A83 WeakPolarHBondContact O-CB 3.49Å; I79-A83 PolarHBondContact O-N 2.91Å; I79-N453 WeakPolarHBondContact CD1-OD1 3.23Å
80V94.3Very high92.1Very high1 Ų142 Ų421%0.00625%0.246CC..Hα-helixtrans-66.8-44175.5176.50000110.2F70 R73 F75 D77 A83 K84 L91 T99F70-V80 HydrophobicContact CD1-CG2 3.81Å; F70-V80 HydrophobicContact CE1-CG2 4.47Å; R73-V80 HydrophobicContact CB-CG2 4.03Å; F75-V80 HydrophobicContact CD2-CG1 4.38Å; D77-V80 HydrophobicContact CB-CB 4.17Å; D77-V80 HydrophobicContact CB-CG2 3.82Å; D77-V80 WeakPolarHBondContact O-CB 3.49Å; D77-V80 PolarHBondContact O-N 3.19Å; V80-A83 PolarHBondContact O-N 2.75Å; V80-K84 PolarHBondContact O-N 2.7Å; V80-L91 HydrophobicContact CG1-CD1 3.92Å; V80-T99 HydrophobicContact CG1-CG2 3.74Å
81Q95Very high92.2Very high84 Ų8442 Ų4239%0.39325%0.247SC..Hα-helixtrans-66.9-42177.3-66.5-61.1-48.600112.5F75 D77 A83 K84F75-Q81 PolarHBondContact O-NE2 2.95Å; D77-Q81 PolarHBondContact O-N 3Å; Q81-A83 VanDerWaalsContact C-N 3.32Å; Q81-A83 PolarHBondContact O-N 2.91Å; Q81-K84 WeakPolarHBondContact O-CB 3.02Å; Q81-K84 PolarHBondContact O-N 2.86Å
82A91.5Very high92.3Very high62 Ų6243.1 Ų43.151%0.51226%0.256SS..Hα-helixtrans-67.5-30.4176.300000113.1P78 S85 N86P78-A82 WeakPolarHBondContact O-CB 3.34Å; P78-A82 PolarHBondContact O-N 2.82Å; A82-S85 PolarHBondContact O-OG 3.08Å; A82-N86 PolarHBondContact O-ND2 3.17Å
83A89.9Confident92.4Very high13 Ų1348.4 Ų48.411%0.10728%0.28CS..Hα-helixtrans-69-33.6174.200000112.6F70 I79 V80 Q81 S85 N86 L87F70-A83 HydrophobicContact CE1-CB 3.66Å; F70-A83 HydrophobicContact CZ-CB 3.69Å; I79-A83 VanDerWaalsContact O-CB 3.31Å; I79-A83 WeakPolarHBondContact O-CB 3.49Å; I79-A83 PolarHBondContact O-N 2.91Å; V80-A83 PolarHBondContact O-N 2.75Å; Q81-A83 VanDerWaalsContact C-N 3.32Å; Q81-A83 PolarHBondContact O-N 2.91Å; A83-S85 VanDerWaalsContact C-N 3.27Å; A83-S85 PolarHBondContact O-N 3.44Å; A83-S85 VanDerWaalsContact O-N 3.13Å; A83-N86 PolarHBondContact O-N 3.02Å; A83-L87 PolarHBondContact O-N 3.46Å
84K89Confident92.4Very high83 Ų8348.4 Ų48.436%0.36128%0.281SS..Hα-helixtrans-55.8-34.3-170.7-173.9167.4178.8160.90114.5V80 Q81 N86 L91V80-K84 PolarHBondContact O-N 2.7Å; Q81-K84 WeakPolarHBondContact O-CB 3.02Å; Q81-K84 PolarHBondContact O-N 2.86Å; K84-N86 VanDerWaalsContact C-N 3.26Å; K84-N86 PolarHBondContact O-N 3.49Å; K84-L91 PolarHBondContact NZ-O 3.12Å
85S83.8Confident92.2Very high101 Ų10154.7 Ų54.771%0.70632%0.321SS*.THydrogen-bonded Turntrans-74.1-12.2177.654.90000114.6A82 A83A82-S85 PolarHBondContact O-OG 3.08Å; A83-S85 VanDerWaalsContact C-N 3.27Å; A83-S85 PolarHBondContact O-N 3.44Å; A83-S85 VanDerWaalsContact O-N 3.13Å
86N82.6Confident91.9Very high87 Ų8756.1 Ų56.147%0.46534%0.335SS..THydrogen-bonded Turntrans-112.85.1-177.4-63.6-71.1000113A82 A83 K84A82-N86 PolarHBondContact O-ND2 3.17Å; A83-N86 PolarHBondContact O-N 3.02Å; K84-N86 VanDerWaalsContact C-N 3.26Å; K84-N86 PolarHBondContact O-N 3.49Å
87L89.3Confident91.8Very high47 Ų4752.7 Ų52.725%0.24631%0.313CS..  trans-98.4158.2175.9-66.5176.7000111.6F70 A83 Y89 L91F70-L87 HydrophobicContact CE2-CD1 4.05Å; F70-L87 HydrophobicContact CZ-CD1 3.97Å; A83-L87 PolarHBondContact O-N 3.46Å; L87-Y89 HydrophobicContact CD1-CE2 3.85Å; L87-Y89 HydrophobicContact CD2-CE1 3.9Å; L87-Y89 HydrophobicContact CD2-CE2 4.47Å; L87-L91 HydrophobicContact CD1-CD1 3.61Å; L87-L91 HydrophobicContact CD1-CD2 4.16Å; L87-L91 HydrophobicContact CD1-CG 3.74Å
88V89.9Confident91.8Very high33 Ų3353.1 Ų53.120%0.232%0.317CS..SBendtrans-104.9-23.3176.91760000112.3C60 P260 V264C60-V88 HydrophobicContact CB-CG1 3.82Å; V88-P260 HydrophobicContact CB-CB 4.45Å; V88-P260 HydrophobicContact CG1-CB 3.58Å; V88-P260 HydrophobicContact CG2-CB 4.12Å; V88-V264 HydrophobicContact CG2-CG2 3.98Å
89Y92.8Very high92Very high9 Ų948.9 Ų48.94%0.03529%0.29CS..SBendtrans-96.6156.117059.8-95.4000110.2K61 V64 Q65 L87 L91 I101K61-Y89 WeakPolarHBondContact O-CA 3.45Å; K61-Y89 WeakPolarHBondContact O-CB 3.36Å; V64-Y89 HydrophobicContact CB-CD1 4.5Å; V64-Y89 HydrophobicContact CB-CE1 4.47Å; V64-Y89 HydrophobicContact CG1-CD1 4.3Å; V64-Y89 HydrophobicContact CG1-CD2 4.27Å; V64-Y89 HydrophobicContact CG1-CE1 3.93Å; V64-Y89 HydrophobicContact CG1-CE2 3.88Å; V64-Y89 HydrophobicContact CG1-CG 4.46Å; Q65-Y89 WeakPolarHBondContact O-CE1 3.25Å; Q65-Y89 PolarHBondContact O-OH 2.8Å; L87-Y89 HydrophobicContact CD1-CE2 3.85Å; L87-Y89 HydrophobicContact CD2-CE1 3.9Å; L87-Y89 HydrophobicContact CD2-CE2 4.47Å; Y89-L91 HydrophobicContact CD2-CD2 4.39Å; Y89-L91 HydrophobicContact CE2-CD2 3.89Å; Y89-I101 HydrophobicContact CD2-CG2 3.87Å; Y89-I101 HydrophobicContact CE2-CG1 4.22Å; Y89-I101 HydrophobicContact CE2-CG2 4.11Å
90D94.6Very high92.3Very high82 Ų8247 Ų4744%0.43928%0.28SS..EExtended strand (participates in β ladder)trans-83.8143.3-176.2-85-58.4000112.8K102D90-K102 HydrophobicContact CB-CB 3.92Å; D90-K102 HydrophobicContact CB-CD 4.16Å; D90-K102 HydrophobicContact CB-CG 4.1Å; D90-K102 PolarHBondContact O-N 3.05Å
91L96.8Very high92.4Very high4 Ų447 Ų472%0.02128%0.28CS..EExtended strand (participates in β ladder)trans-104.8134.8166.8-63.5-177.6000110.6F70 F75 V80 K84 L87 Y89 T99 G100 I101F70-L91 HydrophobicContact CD2-CD2 4.42Å; F70-L91 HydrophobicContact CE2-CD1 4.19Å; F70-L91 HydrophobicContact CE2-CD2 4.24Å; F70-L91 HydrophobicContact CZ-CD1 4.16Å; F75-L91 HydrophobicContact CE2-CB 3.98Å; V80-L91 HydrophobicContact CG1-CD1 3.92Å; K84-L91 PolarHBondContact NZ-O 3.12Å; L87-L91 HydrophobicContact CD1-CD1 3.61Å; L87-L91 HydrophobicContact CD1-CD2 4.16Å; L87-L91 HydrophobicContact CD1-CG 3.74Å; Y89-L91 HydrophobicContact CD2-CD2 4.39Å; Y89-L91 HydrophobicContact CE2-CD2 3.89Å; L91-T99 HydrophobicContact CD2-CG2 4.25Å; L91-G100 WeakPolarHBondContact CA-O 2.9Å; L91-I101 HydrophobicContact CD2-CG1 3.69Å
92A96.6Very high92.6Very high22 Ų2246 Ų4618%0.18227%0.274CS..EExtended strand (participates in β ladder)trans-127.5165.3179.700000111.4F75 G100 K102 V111F75-A92 VanDerWaalsContact CD2-C 3.46Å; F75-A92 WeakPolarHBondContact CD2-O 3.23Å; A92-G100 PolarHBondContact N-O 3.26Å; A92-G100 WeakPolarHBondContact O-CA 3.46Å; A92-G100 PolarHBondContact O-N 2.86Å; A92-G100 VanDerWaalsContact O-O 3.09Å; A92-K102 HydrophobicContact CB-CB 4.22Å; A92-V111 HydrophobicContact CB-CG1 4.08Å; A92-V111 HydrophobicContact CB-CG2 4.24Å
93Q96.6Very high92.8Very high115 Ų11543.3 Ų43.354%0.53725%0.252SS..EExtended strand (participates in β ladder)trans-93.2126.4175.7-170.3164.512.700109.9F75F75-Q93 HydrophobicContact CB-CB 3.93Å; F75-Q93 HydrophobicContact CB-CG 3.8Å; F75-Q93 HydrophobicContact CD1-CB 3.66Å; F75-Q93 HydrophobicContact CD1-CG 4.08Å; F75-Q93 HydrophobicContact CD2-CB 4.44Å; F75-Q93 HydrophobicContact CE1-CB 4.26Å; F75-Q93 HydrophobicContact CG-CB 3.75Å; F75-Q93 HydrophobicContact CG-CG 4.14Å
94M94.1Very high93.2Very high17 Ų1746.9 Ų46.98%0.08427%0.268CS..  trans-68.2157.4169.9-65.4-65.9-72.200110.5S96 G97 A98 V111 F596M94-S96 PolarHBondContact O-N 3.48Å; M94-S96 VanDerWaalsContact O-N 3.14Å; M94-G97 WeakPolarHBondContact O-CA 3.44Å; M94-G97 PolarHBondContact O-N 3.34Å; M94-A98 HydrophobicContact CB-CB 4.21Å; M94-A98 WeakPolarHBondContact CB-O 3.22Å; M94-A98 HydrophobicContact CG-CB 4.31Å; M94-A98 PolarHBondContact N-O 2.84Å; M94-V111 HydrophobicContact SD-CG1 3.82Å; M94-F596 HydrophobicContact CE-CZ 4.31Å
95P91.7Very high93.6Very high137 Ų13743.6 Ų43.689%0.8925%0.254SS*.THydrogen-bonded Turntrans-55.7-30173.9-26.435.7000113.9G97P95-G97 PolarHBondContact O-N 3.3Å
96S89.1Confident94.1Very high61 Ų6142.7 Ų42.743%0.42724%0.239SC..THydrogen-bonded Turntrans-73.3-6.3173.356.40000114.6M94 A98M94-S96 PolarHBondContact O-N 3.48Å; M94-S96 VanDerWaalsContact O-N 3.14Å; S96-A98 VanDerWaalsContact C-N 3.28Å; S96-A98 PolarHBondContact O-N 3.47Å
97G93.1Very high94.6Very high14 Ų1445.9 Ų45.914%0.14425%0.251CS..SBendtrans82.8-5.1-172.700000115F75 M94 P95F75-G97 PolarHBondContact N-O 3.42Å; M94-G97 WeakPolarHBondContact O-CA 3.44Å; M94-G97 PolarHBondContact O-N 3.34Å; P95-G97 PolarHBondContact O-N 3.3Å
98A93.5Very high95Very high14 Ų1448.5 Ų48.512%0.11626%0.262CS..BIsolated β-bridgetrans-66.5163.9174.700000112.5M94 S96 G100 W586M94-A98 HydrophobicContact CB-CB 4.21Å; M94-A98 WeakPolarHBondContact CB-O 3.22Å; M94-A98 HydrophobicContact CG-CB 4.31Å; M94-A98 PolarHBondContact N-O 2.84Å; S96-A98 VanDerWaalsContact C-N 3.28Å; S96-A98 PolarHBondContact O-N 3.47Å; A98-G100 PolarHBondContact O-N 3.15Å; A98-W586 HydrophobicContact CB-CE3 4.35Å
99T96.3Very high95.3Very high2 Ų252.8 Ų52.81%0.01228%0.28CS..EExtended strand (participates in β ladder)trans-72.2124.2174.4-53.70000110.7F70 R73 A74 F75 V80 L91F70-T99 HydrophobicContact CB-CG2 4.11Å; F70-T99 HydrophobicContact CG-CG2 4.37Å; R73-T99 WeakPolarHBondContact O-CB 3.15Å; R73-T99 PolarHBondContact O-N 2.98Å; R73-T99 PolarHBondContact O-OG1 3.28Å; A74-T99 PolarHBondContact O-OG1 3.31Å; F75-T99 PolarHBondContact N-OG1 3.49Å; V80-T99 HydrophobicContact CG1-CG2 3.74Å; L91-T99 HydrophobicContact CD2-CG2 4.25Å
100G96.9Very high95.5Very high0 Ų058.1 Ų58.10%030%0.3CS..EExtended strand (participates in β ladder)trans-113.5154170.600000111.6L91 A92 A98 F112L91-G100 WeakPolarHBondContact CA-O 2.9Å; A92-G100 PolarHBondContact N-O 3.26Å; A92-G100 WeakPolarHBondContact O-CA 3.46Å; A92-G100 PolarHBondContact O-N 2.86Å; A92-G100 VanDerWaalsContact O-O 3.09Å; A98-G100 PolarHBondContact O-N 3.15Å; G100-F112 CarbonylContact C-O 3.48Å; G100-F112 WeakPolarHBondContact CA-O 3.16Å
101I97.9Very high95.7Very high0 Ų057 Ų570%030%0.296CS..EExtended strand (participates in β ladder)trans-112.7121.7179.5-69.6156.8000107.9V64 F67 Y89 L91 V103 V111 F112 V114 I117V64-I101 HydrophobicContact CG1-CD1 4.09Å; V64-I101 HydrophobicContact CG1-CG2 3.85Å; V64-I101 HydrophobicContact CG2-CG2 3.75Å; F67-I101 HydrophobicContact CB-CD1 3.67Å; Y89-I101 HydrophobicContact CD2-CG2 3.87Å; Y89-I101 HydrophobicContact CE2-CG1 4.22Å; Y89-I101 HydrophobicContact CE2-CG2 4.11Å; L91-I101 HydrophobicContact CD2-CG1 3.69Å; I101-V103 HydrophobicContact CG2-CG1 4.26Å; I101-V111 WeakPolarHBondContact O-CA 3.45Å; I101-F112 PolarHBondContact N-O 3.32Å; I101-F112 PolarHBondContact O-N 2.8Å; I101-V114 HydrophobicContact CD1-CG2 4.37Å; I101-I117 HydrophobicContact CB-CG1 4.45Å; I101-I117 HydrophobicContact CD1-CG1 3.9Å
102K97.6Very high95.7Very high63 Ų6357.6 Ų57.627%0.27430%0.298SS..EExtended strand (participates in β ladder)trans-99.4126.4-173.7166.2173.2162.1151.10110.3D90 A92 E109 R110 V111D90-K102 HydrophobicContact CB-CB 3.92Å; D90-K102 HydrophobicContact CB-CD 4.16Å; D90-K102 HydrophobicContact CB-CG 4.1Å; D90-K102 PolarHBondContact O-N 3.05Å; A92-K102 HydrophobicContact CB-CB 4.22Å; K102-E109 HydrophobicContact CD-CG 4.38Å; K102-E109 VanDerWaalsContact CE-OE1 3.24Å; K102-E109 WeakPolarHBondContact CE-OE1 3.37Å; K102-E109 WeakPolarHBondContact CE-OE2 3.19Å; K102-E109 HydrophobicContact CG-CG 4.27Å; K102-E109 IonicContact NZ-OE1 3.91Å; K102-E109 PolarHBondContact NZ-OE1 3.38Å; K102-E109 IonicContact NZ-OE2 3.31Å; K102-E109 PolarHBondContact NZ-OE2 2.93Å; K102-R110 WeakPolarHBondContact CA-O 3.41Å; K102-V111 HydrophobicContact CB-CG2 4.25Å
103V97.4Very high95.8Very high6 Ų656.6 Ų56.64%0.03629%0.29CS..EExtended strand (participates in β ladder)trans-144.7160.5-176.8-660000110.9F41 N62 V64 I101 R110 F112F41-V103 HydrophobicContact CB-CB 4.39Å; F41-V103 HydrophobicContact CB-CG2 4.26Å; F41-V103 HydrophobicContact CD1-CG2 4.24Å; F41-V103 HydrophobicContact CD2-CB 3.99Å; F41-V103 HydrophobicContact CD2-CG1 3.85Å; F41-V103 HydrophobicContact CD2-CG2 3.7Å; F41-V103 HydrophobicContact CE2-CG1 4.23Å; F41-V103 HydrophobicContact CE2-CG2 4.06Å; F41-V103 HydrophobicContact CG-CB 4.28Å; F41-V103 HydrophobicContact CG-CG2 3.8Å; F41-V103 HydrophobicContact CZ-CG2 4.46Å; N62-V103 HydrophobicContact CB-CB 4.48Å; V64-V103 HydrophobicContact CG2-CG1 3.89Å; I101-V103 HydrophobicContact CG2-CG1 4.26Å; V103-R110 PolarHBondContact N-O 3.34Å; V103-R110 PolarHBondContact O-N 3.12Å; V103-F112 HydrophobicContact CG2-CD2 3.78Å; V103-F112 HydrophobicContact CG2-CE2 3.74Å
104L97.6Very high95.8Very high87 Ų8751.2 Ų51.246%0.45527%0.265SS..EExtended strand (participates in β ladder)trans-87.7123.2163.3-160.677.7000109F41 N62 E108F41-L104 WeakPolarHBondContact CB-O 3.35Å; N62-L104 WeakPolarHBondContact OD1-CB 3.45Å; N62-L104 PolarHBondContact OD1-N 3.1Å; L104-E108 WeakPolarHBondContact CA-O 3.46Å
105Y97.3Very high96Very high14 Ų1450.8 Ų50.86%0.05526%0.263CS..EExtended strand (participates in β ladder)trans-139.7129.8177.1175.8-122.6000109.8F41 R46 E107 E108 F112 M603F41-Y105 HydrophobicContact CB-CD2 4.12Å; F41-Y105 HydrophobicContact CB-CG 4.46Å; F41-Y105 AromaticContact CD1-CD2 3.72Å; F41-Y105 HydrophobicContact CD1-CD2 3.72Å; F41-Y105 HydrophobicContact CD1-CE2 4.39Å; F41-Y105 AromaticContact CD1-CG 3.81Å; F41-Y105 HydrophobicContact CD1-CG 3.81Å; F41-Y105 HydrophobicContact CG-CD2 4.43Å; R46-Y105 HydrophobicContact CB-CE2 4.43Å; Y105-E107 PolarHBondContact O-N 3.26Å; Y105-E108 PolarHBondContact N-O 2.98Å; Y105-E108 PolarHBondContact O-N 3.48Å; Y105-E108 VanDerWaalsContact O-N 3.09Å; Y105-F112 HydrophobicContact CD1-CZ 4.08Å; Y105-M603 HydrophobicContact CE1-CG 4.04Å; Y105-M603 HydrophobicContact CE1-SD 4.04Å
106M94.9Very high96.3Very high82 Ų8244.9 Ų44.940%0.40422%0.223SC..THydrogen-bonded Turntrans51.242.3-172.3-58.5-175.570.900112.2G42 P43 E108 Q606G42-M106 PolarHBondContact O-N 2.98Å; P43-M106 WeakPolarHBondContact O-CA 3.4Å; M106-E108 PolarHBondContact O-N 2.9Å; M106-Q606 HydrophobicContact CE-CG 4.25Å; M106-Q606 HydrophobicContact SD-CG 4.13Å
107E93.6Very high96.8Very high155 Ų15542 Ų4272%0.72420%0.203SC*.THydrogen-bonded Turntrans63.4-0.2-177.7-49.4-167.3144.200115.9P43 Y105P43-E107 HydrophobicContact CB-CG 4.02Å; Y105-E107 PolarHBondContact O-N 3.26Å
108E96.4Very high97.1Very high101 Ų10141.3 Ų41.347%0.47220%0.196SC..EExtended strand (participates in β ladder)trans-100149.8175.4-66-176.115600112.6L104 Y105 M106 R110L104-E108 WeakPolarHBondContact CA-O 3.46Å; Y105-E108 PolarHBondContact N-O 2.98Å; Y105-E108 PolarHBondContact O-N 3.48Å; Y105-E108 VanDerWaalsContact O-N 3.09Å; M106-E108 PolarHBondContact O-N 2.9Å; E108-R110 HydrophobicContact CB-CG 4.48Å; E108-R110 PolarHBondContact O-N 3.44Å; E108-R110 IonicContact OE2-CZ 2.82Å; E108-R110 IonicContact OE2-NE 3.47Å; E108-R110 PolarHBondContact OE2-NE 3.25Å; E108-R110 IonicContact OE2-NH2 3Å; E108-R110 PolarHBondContact OE2-NH2 3.2Å
109E97.1Very high97.3Very high123 Ų12340.6 Ų40.658%0.57519%0.191SC*.EExtended strand (participates in β ladder)trans-74.2118.2168.1-178.1173.9133.700110K102K102-E109 HydrophobicContact CD-CG 4.38Å; K102-E109 VanDerWaalsContact CE-OE1 3.24Å; K102-E109 WeakPolarHBondContact CE-OE1 3.37Å; K102-E109 WeakPolarHBondContact CE-OE2 3.19Å; K102-E109 HydrophobicContact CG-CG 4.27Å; K102-E109 IonicContact NZ-OE1 3.91Å; K102-E109 PolarHBondContact NZ-OE1 3.38Å; K102-E109 IonicContact NZ-OE2 3.31Å; K102-E109 PolarHBondContact NZ-OE2 2.93Å
110R96.9Very high97.4Very high122 Ų12240.5 Ų40.546%0.4619%0.19SC..EExtended strand (participates in β ladder)trans-123.4142.8178.2-62.7-59.1-168.9126.7-6.1110.5K102 V103 E108 F112K102-R110 WeakPolarHBondContact CA-O 3.41Å; V103-R110 PolarHBondContact N-O 3.34Å; V103-R110 PolarHBondContact O-N 3.12Å; E108-R110 HydrophobicContact CB-CG 4.48Å; E108-R110 PolarHBondContact O-N 3.44Å; E108-R110 IonicContact OE2-CZ 2.82Å; E108-R110 IonicContact OE2-NE 3.47Å; E108-R110 PolarHBondContact OE2-NE 3.25Å; E108-R110 IonicContact OE2-NH2 3Å; E108-R110 PolarHBondContact OE2-NH2 3.2Å; R110-F112 HydrophobicContact CB-CD2 4.44Å; R110-F112 HydrophobicContact CB-CE2 3.81Å; R110-F112 HydrophobicContact CB-CZ 4.11Å
111V97.7Very high97.5Very high57 Ų5740.5 Ų40.535%0.34519%0.19SC..EExtended strand (participates in β ladder)trans-113.5122.6171.5-173.80000108.1A92 M94 I101 K102A92-V111 HydrophobicContact CB-CG1 4.08Å; A92-V111 HydrophobicContact CB-CG2 4.24Å; M94-V111 HydrophobicContact SD-CG1 3.82Å; I101-V111 WeakPolarHBondContact O-CA 3.45Å; K102-V111 HydrophobicContact CB-CG2 4.25Å
112F98.1Very high97.5Very high17 Ų1740.5 Ų40.58%0.07519%0.19CC..EExtended strand (participates in β ladder)trans-110.4143.7177.5-65.4-78.5000110.6F41 G100 I101 V103 Y105 R110 Q116 I117 M120 M603F41-F112 AromaticContact CD1-CE2 3.93Å; F41-F112 HydrophobicContact CD1-CE2 3.93Å; F41-F112 HydrophobicContact CD1-CZ 4.44Å; F41-F112 AromaticContact CE1-CD2 3.95Å; F41-F112 HydrophobicContact CE1-CD2 3.95Å; F41-F112 AromaticContact CE1-CE2 3.41Å; F41-F112 HydrophobicContact CE1-CE2 3.41Å; F41-F112 VanDerWaalsContact CE1-CE2 3.41Å; F41-F112 AromaticContact CE1-CZ 3.85Å; F41-F112 HydrophobicContact CE1-CZ 3.85Å; F41-F112 AromaticContact CZ-CD2 3.86Å; F41-F112 HydrophobicContact CZ-CD2 3.86Å; F41-F112 AromaticContact CZ-CE2 3.83Å; F41-F112 HydrophobicContact CZ-CE2 3.83Å; G100-F112 CarbonylContact C-O 3.48Å; G100-F112 WeakPolarHBondContact CA-O 3.16Å; I101-F112 PolarHBondContact N-O 3.32Å; I101-F112 PolarHBondContact O-N 2.8Å; V103-F112 HydrophobicContact CG2-CD2 3.78Å; V103-F112 HydrophobicContact CG2-CE2 3.74Å; Y105-F112 HydrophobicContact CD1-CZ 4.08Å; R110-F112 HydrophobicContact CB-CD2 4.44Å; R110-F112 HydrophobicContact CB-CE2 3.81Å; R110-F112 HydrophobicContact CB-CZ 4.11Å; F112-Q116 VanDerWaalsContact CA-OE1 3.31Å; F112-Q116 HydrophobicContact CB-CB 4.29Å; F112-Q116 HydrophobicContact CD1-CB 4.43Å; F112-I117 HydrophobicContact CB-CD1 3.7Å; F112-I117 HydrophobicContact CB-CG1 4.07Å; F112-I117 HydrophobicContact CD2-CD1 4.29Å; F112-I117 HydrophobicContact CG-CD1 4.18Å; F112-M120 HydrophobicContact CD1-CE 3.68Å; F112-M120 HydrophobicContact CD2-CE 4.46Å; F112-M120 HydrophobicContact CE1-CE 3.8Å; F112-M120 HydrophobicContact CG-CE 4.03Å; F112-M120 HydrophobicContact CZ-CE 4.25Å; F112-M603 HydrophobicContact CE1-CE 4.12Å; F112-M603 HydrophobicContact CE1-SD 3.84Å; F112-M603 HydrophobicContact CZ-SD 4.01Å
113S97.6Very high97.5Very high2 Ų237.8 Ų37.81%0.01418%0.179CC..EExtended strand (participates in β ladder)trans-71.8162.3171.696.40000111.3E115 Q116 I117S113-E115 WeakPolarHBondContact CB-OE2 3.35Å; S113-E115 PolarHBondContact O-N 2.95Å; S113-E115 WeakPolarHBondContact OG-CB 3.33Å; S113-E115 PolarHBondContact OG-N 2.97Å; S113-E115 PolarHBondContact OG-OE2 3.45Å; S113-Q116 WeakPolarHBondContact O-CB 3.39Å; S113-Q116 PolarHBondContact O-N 3.47Å; S113-Q116 VanDerWaalsContact O-N 3.16Å; S113-Q116 PolarHBondContact OG-N 3.42Å; S113-I117 WeakPolarHBondContact O-CG1 3.43Å; S113-I117 PolarHBondContact O-N 2.72Å
114V97.8Very high97.6Very high1 Ų138.6 Ų38.61%0.00618%0.182CC..Hα-helixtrans-64.8-34.8177.6-172.20000110.8F67 F70 I101 Q116 I117 T118F67-V114 HydrophobicContact CD2-CG1 4.46Å; F70-V114 HydrophobicContact CB-CG1 4.46Å; F70-V114 HydrophobicContact CB-CG2 3.73Å; I101-V114 HydrophobicContact CD1-CG2 4.37Å; V114-Q116 VanDerWaalsContact C-N 3.34Å; V114-I117 PolarHBondContact O-N 2.82Å; V114-T118 WeakPolarHBondContact O-CB 3.33Å; V114-T118 PolarHBondContact O-N 2.76Å; V114-T118 PolarHBondContact O-OG1 3.1Å
115E98.1Very high97.6Very high9 Ų934.5 Ų34.54%0.04216%0.16CC..Hα-helixtrans-59.8-43.7173-56.566.8-14700110.8S113 G119 S155 D158 A159 I162 L588S113-E115 WeakPolarHBondContact CB-OE2 3.35Å; S113-E115 PolarHBondContact O-N 2.95Å; S113-E115 WeakPolarHBondContact OG-CB 3.33Å; S113-E115 PolarHBondContact OG-N 2.97Å; S113-E115 PolarHBondContact OG-OE2 3.45Å; E115-G119 PolarHBondContact O-N 3Å; E115-S155 WeakPolarHBondContact OE1-CB 3.32Å; E115-S155 PolarHBondContact OE1-OG 2.95Å; E115-D158 HydrophobicContact CG-CB 4.29Å; E115-A159 HydrophobicContact CB-CB 4.43Å; E115-A159 VanDerWaalsContact O-CB 3.3Å; E115-A159 WeakPolarHBondContact O-CB 3.48Å; E115-I162 HydrophobicContact CB-CD1 3.88Å; E115-L588 HydrophobicContact CB-CD1 4.1Å; E115-L588 HydrophobicContact CG-CD1 3.98Å; E115-L588 HydrophobicContact CG-CG 4.43Å
116Q98.4Very high97.6Very high12 Ų1235.6 Ų35.66%0.05617%0.165CC..Hα-helixtrans-64.3-49.8176.2-66.5-179.5-64.500111.8F112 S113 V114 T118 G119 M120 I162 F596F112-Q116 VanDerWaalsContact CA-OE1 3.31Å; F112-Q116 HydrophobicContact CB-CB 4.29Å; F112-Q116 HydrophobicContact CD1-CB 4.43Å; S113-Q116 WeakPolarHBondContact O-CB 3.39Å; S113-Q116 PolarHBondContact O-N 3.47Å; S113-Q116 VanDerWaalsContact O-N 3.16Å; S113-Q116 PolarHBondContact OG-N 3.42Å; V114-Q116 VanDerWaalsContact C-N 3.34Å; Q116-T118 VanDerWaalsContact C-N 3.33Å; Q116-T118 PolarHBondContact O-N 2.89Å; Q116-G119 WeakPolarHBondContact O-CA 3.39Å; Q116-G119 PolarHBondContact O-N 3.08Å; Q116-M120 WeakPolarHBondContact O-CG 3.42Å; Q116-M120 PolarHBondContact O-N 3.14Å; Q116-I162 HydrophobicContact CG-CD1 4.26Å; Q116-F596 HydrophobicContact CG-CB 4.1Å; Q116-F596 HydrophobicContact CG-CD1 4.23Å; Q116-F596 HydrophobicContact CG-CD2 3.46Å; Q116-F596 VanDerWaalsContact CG-CD2 3.46Å; Q116-F596 HydrophobicContact CG-CE2 3.85Å; Q116-F596 HydrophobicContact CG-CG 3.67Å; Q116-F596 HydrophobicContact CG-CZ 4.39Å; Q116-F596 VanDerWaalsContact NE2-CD1 3.3Å
117I98.6Very high97.8Very high0 Ų035.1 Ų35.10%016%0.162CC..Hα-helixtrans-59-43.6178.7-60.3-61.2000111.2V39 F41 V64 F67 I101 F112 S113 V114 G119 M120 L121V39-I117 HydrophobicContact CB-CG2 4.4Å; V39-I117 HydrophobicContact CG2-CG2 3.96Å; F41-I117 HydrophobicContact CE2-CD1 3.8Å; F41-I117 HydrophobicContact CZ-CD1 3.54Å; V64-I117 HydrophobicContact CG1-CG2 4.33Å; F67-I117 HydrophobicContact CD1-CG2 3.79Å; F67-I117 HydrophobicContact CD2-CB 4.24Å; F67-I117 HydrophobicContact CD2-CG2 3.63Å; F67-I117 HydrophobicContact CE1-CG2 3.8Å; F67-I117 HydrophobicContact CE2-CB 4.42Å; F67-I117 HydrophobicContact CE2-CG2 3.66Å; F67-I117 HydrophobicContact CG-CG2 3.7Å; F67-I117 HydrophobicContact CZ-CG2 3.73Å; I101-I117 HydrophobicContact CB-CG1 4.45Å; I101-I117 HydrophobicContact CD1-CG1 3.9Å; F112-I117 HydrophobicContact CB-CD1 3.7Å; F112-I117 HydrophobicContact CB-CG1 4.07Å; F112-I117 HydrophobicContact CD2-CD1 4.29Å; F112-I117 HydrophobicContact CG-CD1 4.18Å; S113-I117 WeakPolarHBondContact O-CG1 3.43Å; S113-I117 PolarHBondContact O-N 2.72Å; V114-I117 PolarHBondContact O-N 2.82Å; I117-G119 VanDerWaalsContact C-N 3.33Å; I117-M120 HydrophobicContact CD1-CE 4.16Å; I117-M120 PolarHBondContact O-N 3.02Å; I117-L121 PolarHBondContact O-N 3.1Å
118T98.5Very high98Very high0 Ų028 Ų280%013%0.129CC..Hα-helixtrans-66.6-34.7174.4-63.60000112L8 F67 H71 V114 Q116 L121 L122 A159L8-T118 HydrophobicContact CD2-CG2 3.87Å; F67-T118 WeakPolarHBondContact CE2-OG1 3.17Å; H71-T118 PolarHBondContact CE1-OG1 3.23Å; H71-T118 PolarHBondContact NE2-OG1 2.9Å; V114-T118 WeakPolarHBondContact O-CB 3.33Å; V114-T118 PolarHBondContact O-N 2.76Å; V114-T118 PolarHBondContact O-OG1 3.1Å; Q116-T118 VanDerWaalsContact C-N 3.33Å; Q116-T118 PolarHBondContact O-N 2.89Å; T118-L121 PolarHBondContact O-N 3.02Å; T118-L122 HydrophobicContact CG2-CD1 4.02Å; T118-L122 HydrophobicContact CG2-CG 4.32Å; T118-L122 WeakPolarHBondContact O-CB 3.39Å; T118-L122 WeakPolarHBondContact O-CG 3.45Å; T118-L122 PolarHBondContact O-N 3.37Å; T118-A159 HydrophobicContact CG2-CB 3.68Å
119G98.5Very high98Very high0 Ų023.1 Ų23.10%011%0.106CC..Hα-helixtrans-57-46.3170.700000112.2E115 Q116 I117 L121 L122 T123 A159E115-G119 PolarHBondContact O-N 3Å; Q116-G119 WeakPolarHBondContact O-CA 3.39Å; Q116-G119 PolarHBondContact O-N 3.08Å; I117-G119 VanDerWaalsContact C-N 3.33Å; G119-L121 VanDerWaalsContact C-N 3.32Å; G119-L121 PolarHBondContact O-N 3.36Å; G119-L122 PolarHBondContact O-N 2.83Å; G119-T123 PolarHBondContact O-N 3.14Å; G119-T123 PolarHBondContact O-OG1 2.96Å; G119-A159 WeakPolarHBondContact CA-O 3.31Å
120M98.7Very high98Very high0 Ų019.9 Ų19.90%09%0.091CC..Hα-helixtrans-59-43.6175.8-38.8-159.6-179.400111.7V39 F41 R46 I48 F112 Q116 I117 T123 K124 M603V39-M120 HydrophobicContact CG1-CB 4.4Å; V39-M120 HydrophobicContact CG1-SD 3.89Å; V39-M120 HydrophobicContact CG2-CB 4.31Å; F41-M120 HydrophobicContact CE1-CE 3.86Å; F41-M120 HydrophobicContact CE1-SD 3.69Å; F41-M120 HydrophobicContact CZ-CE 3.79Å; F41-M120 HydrophobicContact CZ-SD 3.55Å; F41-M120 VanDerWaalsContact CZ-SD 3.55Å; R46-M120 PolarHBondContact NH1-SD 2.83Å; I48-M120 HydrophobicContact CD1-CB 3.99Å; I48-M120 WeakPolarHBondContact CD1-O 3.34Å; F112-M120 HydrophobicContact CD1-CE 3.68Å; F112-M120 HydrophobicContact CD2-CE 4.46Å; F112-M120 HydrophobicContact CE1-CE 3.8Å; F112-M120 HydrophobicContact CG-CE 4.03Å; F112-M120 HydrophobicContact CZ-CE 4.25Å; Q116-M120 WeakPolarHBondContact O-CG 3.42Å; Q116-M120 PolarHBondContact O-N 3.14Å; I117-M120 HydrophobicContact CD1-CE 4.16Å; I117-M120 PolarHBondContact O-N 3.02Å; M120-T123 WeakPolarHBondContact O-CB 3.48Å; M120-T123 PolarHBondContact O-N 3.5Å; M120-K124 PolarHBondContact O-N 2.83Å; M120-K124 VanDerWaalsContact O-N 3.1Å; M120-M603 HydrophobicContact CE-CE 3.69Å; M120-M603 HydrophobicContact CE-SD 3.99Å
121L98.6Very high97.9Very high0 Ų017.6 Ų17.60%09%0.094CC..Hα-helixtrans-65.4-42.5177.1-177.357.9000111.6L8 I48 F67 I117 T118 G119 K124 L125L8-L121 HydrophobicContact CD1-CD2 4.03Å; L8-L121 HydrophobicContact CD1-CG 4.32Å; I48-L121 HydrophobicContact CG2-CD1 4.22Å; F67-L121 HydrophobicContact CZ-CD2 3.86Å; I117-L121 PolarHBondContact O-N 3.1Å; T118-L121 PolarHBondContact O-N 3.02Å; G119-L121 VanDerWaalsContact C-N 3.32Å; G119-L121 PolarHBondContact O-N 3.36Å; L121-K124 WeakPolarHBondContact O-CB 3.21Å; L121-K124 PolarHBondContact O-N 3.03Å; L121-K124 VanDerWaalsContact O-N 3.13Å; L121-L125 WeakPolarHBondContact O-CG 3.45Å; L121-L125 PolarHBondContact O-N 3.05Å
122L98.7Very high97.8Very high0 Ų015.8 Ų15.80%09%0.085CC..Hα-helixtrans-65-38.1175.6-74.4170.9000112.4F6 L8 T118 G119 K124 L125 K126 I142 A159 A160 A163 L165F6-L122 HydrophobicContact CD2-CD2 4.4Å; L8-L122 HydrophobicContact CD1-CD2 3.99Å; L8-L122 HydrophobicContact CD1-CG 4.34Å; L8-L122 HydrophobicContact CD2-CD2 4.48Å; T118-L122 HydrophobicContact CG2-CD1 4.02Å; T118-L122 HydrophobicContact CG2-CG 4.32Å; T118-L122 WeakPolarHBondContact O-CB 3.39Å; T118-L122 WeakPolarHBondContact O-CG 3.45Å; T118-L122 PolarHBondContact O-N 3.37Å; G119-L122 PolarHBondContact O-N 2.83Å; L122-K124 VanDerWaalsContact C-N 3.27Å; L122-K124 PolarHBondContact O-N 2.97Å; L122-L125 HydrophobicContact CD2-CD1 4.48Å; L122-L125 PolarHBondContact O-N 3.26Å; L122-K126 VanDerWaalsContact O-CB 3.28Å; L122-K126 WeakPolarHBondContact O-CB 3.24Å; L122-K126 PolarHBondContact O-N 3.18Å; L122-I142 HydrophobicContact CD1-CD1 4.19Å; L122-I142 HydrophobicContact CD2-CD1 4.01Å; L122-I142 HydrophobicContact CD2-CG1 4.39Å; L122-A159 HydrophobicContact CD1-CB 4.16Å; L122-A160 HydrophobicContact CD1-CB 4.29Å; L122-A163 HydrophobicContact CB-CB 3.67Å; L122-L165 HydrophobicContact CB-CD1 4.11Å
123T98.1Very high97.6Very high5 Ų516.6 Ų16.63%0.0319%0.09CC..Hα-helixtrans-54.9-43.6169-69.70000110.9G119 M120 K126 Q127 E600 I604G119-T123 PolarHBondContact O-N 3.14Å; G119-T123 PolarHBondContact O-OG1 2.96Å; M120-T123 WeakPolarHBondContact O-CB 3.48Å; M120-T123 PolarHBondContact O-N 3.5Å; T123-K126 WeakPolarHBondContact O-CB 3.24Å; T123-K126 PolarHBondContact O-N 2.96Å; T123-Q127 VanDerWaalsContact O-CG 3.32Å; T123-Q127 WeakPolarHBondContact O-CG 3.2Å; T123-Q127 PolarHBondContact O-N 2.84Å; T123-E600 WeakPolarHBondContact CB-OE1 3.33Å; T123-E600 PolarHBondContact OG1-OE1 3.12Å; T123-I604 HydrophobicContact CG2-CD1 3.63Å; T123-I604 HydrophobicContact CG2-CG1 3.81Å
124K98Very high97.4Very high24 Ų2424.7 Ų24.710%0.10413%0.125CC..Hα-helixtrans-67.9-42.1177.5-178.154.4165.6170.10112.8E29 T35 I48 M120 L121 L122 K126 Q127 T128E29-K124 VanDerWaalsContact OE1-CE 3.3Å; E29-K124 WeakPolarHBondContact OE1-CE 3.33Å; E29-K124 IonicContact OE1-NZ 2.64Å; E29-K124 PolarHBondContact OE1-NZ 3.48Å; E29-K124 IonicContact OE2-NZ 3.14Å; E29-K124 PolarHBondContact OE2-NZ 3.07Å; T35-K124 HydrophobicContact CG2-CG 4.42Å; I48-K124 HydrophobicContact CB-CB 4Å; I48-K124 HydrophobicContact CB-CG 4.04Å; I48-K124 HydrophobicContact CD1-CB 4.46Å; I48-K124 HydrophobicContact CG2-CB 3.5Å; I48-K124 HydrophobicContact CG2-CG 3.82Å; M120-K124 PolarHBondContact O-N 2.83Å; M120-K124 VanDerWaalsContact O-N 3.1Å; L121-K124 WeakPolarHBondContact O-CB 3.21Å; L121-K124 PolarHBondContact O-N 3.03Å; L121-K124 VanDerWaalsContact O-N 3.13Å; L122-K124 VanDerWaalsContact C-N 3.27Å; L122-K124 PolarHBondContact O-N 2.97Å; K124-K126 VanDerWaalsContact C-N 3.32Å; K124-K126 PolarHBondContact O-N 3.17Å; K124-Q127 PolarHBondContact O-N 2.87Å; K124-T128 PolarHBondContact O-N 2.94Å; K124-T128 PolarHBondContact O-OG1 2.84Å
125L98.4Very high97.2Very high0 Ų031.3 Ų31.30%015%0.154CC..Hα-helixtrans-65.2-36.8175.6-59.4-178.1000112F6 L8 C13 V15 T35 L121 L122 T128 A129F6-L125 HydrophobicContact CB-CD1 4.37Å; F6-L125 HydrophobicContact CD1-CB 3.65Å; F6-L125 HydrophobicContact CD1-CD1 4.14Å; F6-L125 HydrophobicContact CE1-CB 3.54Å; F6-L125 WeakPolarHBondContact CE1-O 3.49Å; F6-L125 HydrophobicContact CG-CB 4.45Å; F6-L125 HydrophobicContact CG-CD1 4.41Å; F6-L125 HydrophobicContact CZ-CB 4.26Å; L8-L125 HydrophobicContact CD1-CD1 4.11Å; C13-L125 HydrophobicContact CB-CD1 3.73Å; C13-L125 HydrophobicContact CB-CD2 3.71Å; C13-L125 HydrophobicContact CB-CG 4.34Å; V15-L125 HydrophobicContact CG2-CB 3.98Å; V15-L125 HydrophobicContact CG2-CD2 3.8Å; V15-L125 HydrophobicContact CG2-CG 4.38Å; T35-L125 HydrophobicContact CG2-CD2 3.9Å; L121-L125 WeakPolarHBondContact O-CG 3.45Å; L121-L125 PolarHBondContact O-N 3.05Å; L122-L125 HydrophobicContact CD2-CD1 4.48Å; L122-L125 PolarHBondContact O-N 3.26Å; L125-T128 WeakPolarHBondContact O-CB 3.48Å; L125-T128 PolarHBondContact O-N 2.94Å; L125-A129 PolarHBondContact O-N 2.84Å
126K98Very high97Very high38 Ų3835.6 Ų35.617%0.16518%0.182CC..Hα-helixtrans-59.8-50.9170.7172.7178.8175.6168.60111.6F6 L122 T123 K124 T128 A129 E130 V137 A163 G164 L165F6-K126 HydrophobicContact CZ-CB 4.5Å; L122-K126 VanDerWaalsContact O-CB 3.28Å; L122-K126 WeakPolarHBondContact O-CB 3.24Å; L122-K126 PolarHBondContact O-N 3.18Å; T123-K126 WeakPolarHBondContact O-CB 3.24Å; T123-K126 PolarHBondContact O-N 2.96Å; K124-K126 VanDerWaalsContact C-N 3.32Å; K124-K126 PolarHBondContact O-N 3.17Å; K126-T128 VanDerWaalsContact C-N 3.27Å; K126-T128 PolarHBondContact O-N 3.14Å; K126-A129 WeakPolarHBondContact O-CB 3.38Å; K126-A129 PolarHBondContact O-N 3.32Å; K126-E130 HydrophobicContact CG-CG 4.36Å; K126-E130 WeakPolarHBondContact O-CG 3.39Å; K126-E130 PolarHBondContact O-N 3.08Å; K126-V137 VanDerWaalsContact CE-O 3.22Å; K126-V137 WeakPolarHBondContact CE-O 3.5Å; K126-V137 HydrophobicContact CG-CB 4.31Å; K126-A163 PolarHBondContact NZ-O 3.43Å; K126-G164 PolarHBondContact NZ-O 3.2Å; K126-L165 HydrophobicContact CB-CD1 4.47Å; K126-L165 HydrophobicContact CB-CD2 4.32Å; K126-L165 HydrophobicContact CD-CD2 3.83Å; K126-L165 HydrophobicContact CD-CG 4.08Å; K126-L165 HydrophobicContact CG-CD2 4.17Å
127Q97.1Very high96.9Very high71 Ų7135 Ų3533%0.33218%0.18SC..Hα-helixtrans-55.9-39.9175.4-73.5170.10.800112.5T123 K124 S131T123-Q127 VanDerWaalsContact O-CG 3.32Å; T123-Q127 WeakPolarHBondContact O-CG 3.2Å; T123-Q127 PolarHBondContact O-N 2.84Å; K124-Q127 PolarHBondContact O-N 2.87Å; Q127-S131 WeakPolarHBondContact O-CB 3.35Å; Q127-S131 PolarHBondContact O-N 3.04Å; Q127-S131 PolarHBondContact O-OG 2.81Å
128T97.8Very high96.7Very high5 Ų538.9 Ų38.93%0.03120%0.203CC..Hα-helixtrans-63.5-45.9174.1-63.60000111.8V15 V26 A27 N28 K124 L125 K126 S131 A132V15-T128 HydrophobicContact CG2-CG2 4.23Å; V26-T128 HydrophobicContact CG2-CG2 4.02Å; A27-T128 WeakPolarHBondContact O-CG2 3.49Å; N28-T128 HydrophobicContact CB-CG2 4.33Å; K124-T128 PolarHBondContact O-N 2.94Å; K124-T128 PolarHBondContact O-OG1 2.84Å; L125-T128 WeakPolarHBondContact O-CB 3.48Å; L125-T128 PolarHBondContact O-N 2.94Å; K126-T128 VanDerWaalsContact C-N 3.27Å; K126-T128 PolarHBondContact O-N 3.14Å; T128-S131 PolarHBondContact O-N 3Å; T128-A132 PolarHBondContact O-N 3.19Å
129A97.6Very high96.5Very high0 Ų039.9 Ų39.90%021%0.208CC..Hα-helixtrans-63.2-43.9176.700000112.5V4 F6 V15 V17 L125 K126 A132 L133 V137V4-A129 HydrophobicContact CG1-CB 3.8Å; V4-A129 HydrophobicContact CG2-CB 4.05Å; F6-A129 HydrophobicContact CE1-CB 4.38Å; V15-A129 HydrophobicContact CG1-CB 3.86Å; V17-A129 HydrophobicContact CG1-CB 4.34Å; L125-A129 PolarHBondContact O-N 2.84Å; K126-A129 WeakPolarHBondContact O-CB 3.38Å; K126-A129 PolarHBondContact O-N 3.32Å; A129-A132 PolarHBondContact O-N 2.78Å; A129-L133 WeakPolarHBondContact O-CB 3.38Å; A129-L133 WeakPolarHBondContact O-CG 3.33Å; A129-L133 PolarHBondContact O-N 2.9Å; A129-V137 HydrophobicContact CB-CG2 3.94Å
130E96.8Very high96.5Very high54 Ų5439.9 Ų39.925%0.25221%0.208SC..Hα-helixtrans-63.9-41.7176.6-69.2178.714700111.5K126 A132 L133 K134 K135 P136 V137K126-E130 HydrophobicContact CG-CG 4.36Å; K126-E130 WeakPolarHBondContact O-CG 3.39Å; K126-E130 PolarHBondContact O-N 3.08Å; E130-A132 VanDerWaalsContact C-N 3.27Å; E130-A132 PolarHBondContact O-N 3.38Å; E130-L133 PolarHBondContact O-N 2.8Å; E130-K134 WeakPolarHBondContact O-CA 3.43Å; E130-K134 PolarHBondContact O-N 3.38Å; E130-K135 WeakPolarHBondContact CA-O 3.32Å; E130-P136 WeakPolarHBondContact OE1-CA 3.45Å; E130-V137 HydrophobicContact CG-CB 3.71Å; E130-V137 HydrophobicContact CG-CG2 3.6Å; E130-V137 PolarHBondContact OE1-N 2.93Å
131S95.6Very high96.5Very high74 Ų7439.9 Ų39.952%0.51721%0.208SC..Hα-helixtrans-63.3-32.1175.8-64.10000112.8Q127 T128 K134Q127-S131 WeakPolarHBondContact O-CB 3.35Å; Q127-S131 PolarHBondContact O-N 3.04Å; Q127-S131 PolarHBondContact O-OG 2.81Å; T128-S131 PolarHBondContact O-N 3Å; S131-K134 WeakPolarHBondContact O-CD 3.38Å; S131-K134 VanDerWaalsContact O-CE 3.24Å; S131-K134 WeakPolarHBondContact O-CE 3.35Å; S131-K134 PolarHBondContact O-NZ 2.94Å
132A94.8Very high96.5Very high19 Ų1939.9 Ų39.916%0.15721%0.208CC..Hα-helixtrans-82.7-36.817600000113.4R19 V26 T128 A129 E130R19-A132 PolarHBondContact NH2-O 3.3Å; V26-A132 HydrophobicContact CB-CB 3.8Å; V26-A132 HydrophobicContact CG1-CB 3.61Å; V26-A132 HydrophobicContact CG2-CB 4.11Å; T128-A132 PolarHBondContact O-N 3.19Å; A129-A132 PolarHBondContact O-N 2.78Å; E130-A132 VanDerWaalsContact C-N 3.27Å; E130-A132 PolarHBondContact O-N 3.38Å
133L93.9Very high96.5Very high34 Ų3439.9 Ų39.918%0.17821%0.208CC..Hα-helixtrans-86.4-15.8-178.6-70.6175000114V4 V17 A129 E130 K135 V137V4-L133 HydrophobicContact CG2-CD1 3.96Å; V17-L133 HydrophobicContact CB-CD1 4.25Å; V17-L133 HydrophobicContact CB-CD2 4.01Å; V17-L133 HydrophobicContact CB-CG 4.22Å; V17-L133 HydrophobicContact CG1-CD1 4.13Å; V17-L133 HydrophobicContact CG1-CG 4.2Å; V17-L133 HydrophobicContact CG2-CD2 3.89Å; V17-L133 HydrophobicContact CG2-CG 4.36Å; A129-L133 WeakPolarHBondContact O-CB 3.38Å; A129-L133 WeakPolarHBondContact O-CG 3.33Å; A129-L133 PolarHBondContact O-N 2.9Å; E130-L133 PolarHBondContact O-N 2.8Å; L133-K135 HydrophobicContact CB-CB 4.46Å; L133-K135 PolarHBondContact O-N 3.25Å; L133-V137 HydrophobicContact CD1-CG2 4.1Å
134K94.4Very high96.4Very high173 Ų17339.7 Ų39.775%0.75221%0.207SC*.THydrogen-bonded Turntrans5331.1-170.8-53.2-55.7-175.2-163.40112.9E130 S131E130-K134 WeakPolarHBondContact O-CA 3.43Å; E130-K134 PolarHBondContact O-N 3.38Å; S131-K134 WeakPolarHBondContact O-CD 3.38Å; S131-K134 VanDerWaalsContact O-CE 3.24Å; S131-K134 WeakPolarHBondContact O-CE 3.35Å; S131-K134 PolarHBondContact O-NZ 2.94Å
135K92.9Very high96.3Very high140 Ų14038.5 Ų38.561%0.60920%0.202SC*.SBendtrans-148.3149.3-175.7-67.4177-174.3177.10109.3E130 L133E130-K135 WeakPolarHBondContact CA-O 3.32Å; L133-K135 HydrophobicContact CB-CB 4.46Å; L133-K135 PolarHBondContact O-N 3.25Å
136P94.4Very high96.1Very high98 Ų9838.7 Ų38.764%0.63620%0.203SC*.  trans-57.1151.4174.5-24.934.7000113.4S2 E130S2-P136 PolarHBondContact OG-O 3.24Å; E130-P136 WeakPolarHBondContact OE1-CA 3.45Å
137V95.5Very high95.9Very high1 Ų137.6 Ų37.61%0.00620%0.198CC..  trans-120.4118.7176171.60000108.9V4 K126 A129 E130 L133 L165V4-V137 HydrophobicContact CB-CG1 4.2Å; V4-V137 HydrophobicContact CG2-CB 4.42Å; V4-V137 HydrophobicContact CG2-CG1 3.69Å; V4-V137 HydrophobicContact CG2-CG2 3.76Å; K126-V137 VanDerWaalsContact CE-O 3.22Å; K126-V137 WeakPolarHBondContact CE-O 3.5Å; K126-V137 HydrophobicContact CG-CB 4.31Å; A129-V137 HydrophobicContact CB-CG2 3.94Å; E130-V137 HydrophobicContact CG-CB 3.71Å; E130-V137 HydrophobicContact CG-CG2 3.6Å; E130-V137 PolarHBondContact OE1-N 2.93Å; L133-V137 HydrophobicContact CD1-CG2 4.1Å; V137-L165 HydrophobicContact CG1-CD2 3.97Å
138V93.9Very high95.8Very high80 Ų8034.4 Ų34.449%0.48518%0.183SC..  trans-115.5-57.4177.8-179.80000108.6L165 N166V138-L165 CarbonylContact O-C 3.38Å; V138-L165 WeakPolarHBondContact O-CA 3.44Å; V138-N166 HydrophobicContact CG1-CB 4.2Å; V138-N166 PolarHBondContact O-N 3.08Å
139D95.8Very high95.7Very high22 Ų2234.3 Ų34.312%0.11818%0.182CC..EExtended strand (participates in β ladder)trans-84137.7-177.6-47.9-78000112.4M1 N166 L168M1-D139 HydrophobicContact CE-CB 4.37Å; M1-D139 HydrophobicContact CG-CB 4.15Å; M1-D139 WeakPolarHBondContact CG-OD2 3.46Å; M1-D139 HydrophobicContact SD-CB 4.37Å; D139-N166 WeakPolarHBondContact CA-O 3.47Å; D139-N166 PolarHBondContact OD1-ND2 3.37Å; D139-L168 HydrophobicContact CB-CD1 3.96Å; D139-L168 HydrophobicContact CB-CD2 4.32Å; D139-L168 HydrophobicContact CB-CG 4.06Å
140C97.4Very high95.6Very high0 Ų034.6 Ų34.60%018%0.184CC..EExtended strand (participates in β ladder)trans-151.1168.2176.270.30000113.4V4 F6 N166 L168V4-C140 WeakPolarHBondContact O-CA 3.36Å; F6-C140 HydrophobicContact CD2-CB 3.78Å; F6-C140 HydrophobicContact CE2-CB 3.54Å; C140-N166 PolarHBondContact N-O 3.31Å; C140-L168 PolarHBondContact O-N 2.99Å
141V98.6Very high95.5Very high0 Ų032.4 Ų32.40%018%0.175CC..EExtended strand (participates in β ladder)trans-121134.7164.3171.70000108.1V4 G5 F6 L168 R169 M171 C376 Q379 C380 L383V4-V141 PolarHBondContact O-N 3.46Å; V4-V141 VanDerWaalsContact O-N 3.08Å; G5-V141 WeakPolarHBondContact CA-O 3.47Å; F6-V141 PolarHBondContact N-O 2.83Å; V141-L168 HydrophobicContact CG2-CB 4.34Å; V141-R169 WeakPolarHBondContact CA-O 3.44Å; V141-R169 HydrophobicContact CG1-CB 4.4Å; V141-R169 WeakPolarHBondContact CG1-O 3.48Å; V141-R169 HydrophobicContact CG2-CB 4.18Å; V141-M171 HydrophobicContact CG1-CB 3.89Å; V141-M171 HydrophobicContact CG1-SD 4.32Å; V141-C376 HydrophobicContact CB-CB 4.18Å; V141-C376 WeakPolarHBondContact CB-O 3.44Å; V141-C376 HydrophobicContact CG1-CB 3.82Å; V141-Q379 HydrophobicContact CG1-CB 4.23Å; V141-Q379 HydrophobicContact CG1-CG 4.1Å; V141-Q379 HydrophobicContact CG2-CB 4.42Å; V141-Q379 HydrophobicContact CG2-CG 4.11Å; V141-C380 HydrophobicContact CB-CB 4.19Å; V141-C380 HydrophobicContact CG2-CB 3.7Å; V141-L383 HydrophobicContact CG2-CD1 4.32Å
142I98.8Very high95.6Very high0 Ų029.2 Ų29.20%015%0.152CC..EExtended strand (participates in β ladder)trans-118.7135.4-173.7-63166.5000109.5F6 L8 L122 V156 A160 C167 R169 L170 M171F6-I142 HydrophobicContact CB-CG1 4.33Å; F6-I142 HydrophobicContact CD2-CG1 4.01Å; L8-I142 HydrophobicContact CB-CG2 4.17Å; L8-I142 HydrophobicContact CD2-CG2 4Å; L122-I142 HydrophobicContact CD1-CD1 4.19Å; L122-I142 HydrophobicContact CD2-CD1 4.01Å; L122-I142 HydrophobicContact CD2-CG1 4.39Å; I142-V156 HydrophobicContact CG2-CG1 3.99Å; I142-A160 HydrophobicContact CD1-CB 3.73Å; I142-C167 HydrophobicContact CD1-CB 4.39Å; I142-R169 PolarHBondContact N-O 2.81Å; I142-L170 HydrophobicContact CB-CD2 3.97Å; I142-L170 HydrophobicContact CG2-CD2 4.26Å; I142-L170 WeakPolarHBondContact O-CA 3.4Å; I142-M171 PolarHBondContact O-N 2.92Å
143S98.1Very high95.7Very high0 Ų028.6 Ų28.60%015%0.145CC..EExtended strand (participates in β ladder)trans-74.3143.2173.577.80000112.4F6 D7 L8 M171F6-S143 PolarHBondContact O-N 2.81Å; D7-S143 WeakPolarHBondContact CA-OG 3.36Å; D7-S143 PolarHBondContact OD1-OG 3.04Å; L8-S143 PolarHBondContact N-OG 3.27Å; S143-M171 WeakPolarHBondContact CA-O 3.44Å
144V97.4Very high95.9Very high0 Ų028.1 Ų28.10%014%0.141CC..EExtended strand (participates in β ladder)trans-139.1151167-68.40000110.2S146 Y148 V156 L170 M171 N172 E173V144-S146 PolarHBondContact O-N 2.74Å; V144-Y148 HydrophobicContact CB-CD2 3.82Å; V144-Y148 HydrophobicContact CB-CE2 4.39Å; V144-Y148 HydrophobicContact CB-CG 4.38Å; V144-Y148 HydrophobicContact CG1-CD2 3.9Å; V144-Y148 HydrophobicContact CG1-CE2 4.24Å; V144-V156 HydrophobicContact CG1-CB 4.34Å; V144-V156 HydrophobicContact CG1-CG1 4.09Å; V144-V156 HydrophobicContact CG1-CG2 4.17Å; V144-L170 HydrophobicContact CG1-CD1 4.28Å; V144-L170 HydrophobicContact CG1-CD2 4.18Å; V144-L170 HydrophobicContact CG2-CB 4.2Å; V144-M171 PolarHBondContact N-O 2.79Å; V144-N172 CarbonylContact O-C 3.43Å; V144-N172 WeakPolarHBondContact O-CA 3.46Å; V144-E173 VanDerWaalsContact C-CD 3.47Å; V144-E173 WeakPolarHBondContact O-CG 3.46Å; V144-E173 PolarHBondContact O-N 2.81Å
145P96.1Very high96Very high0 Ų019.9 Ų19.90%011%0.106CC..  trans-57.9139.4170.4-2433.9000110.8F10 Y147 Y148 R153 E173F10-P145 HydrophobicContact CE2-CG 3.89Å; F10-P145 HydrophobicContact CZ-CG 4.34Å; P145-Y147 HydrophobicContact CB-CD1 3.81Å; P145-Y147 HydrophobicContact CB-CD2 4.22Å; P145-Y147 HydrophobicContact CB-CE1 3.52Å; P145-Y147 HydrophobicContact CB-CE2 3.96Å; P145-Y147 HydrophobicContact CB-CG 4.15Å; P145-Y147 HydrophobicContact CG-CE1 4.48Å; P145-Y147 PolarHBondContact O-N 3.02Å; P145-Y147 VanDerWaalsContact O-N 3.09Å; P145-Y148 HydrophobicContact CB-CD1 3.94Å; P145-Y148 HydrophobicContact CB-CE1 4.23Å; P145-Y148 HydrophobicContact CG-CD1 3.84Å; P145-Y148 HydrophobicContact CG-CE1 3.65Å; P145-Y148 HydrophobicContact CG-CG 4.45Å; P145-Y148 WeakPolarHBondContact O-CB 3.47Å; P145-Y148 PolarHBondContact O-N 3.47Å; P145-R153 PolarHBondContact O-NH2 3.19Å; P145-E173 VanDerWaalsContact CA-OE2 3.28Å; P145-E173 WeakPolarHBondContact CA-OE2 3.49Å; P145-E173 WeakPolarHBondContact CD-OE1 3.44Å; P145-E173 WeakPolarHBondContact CG-OE1 3.43Å
146S94.1Very high96.3Very high3 Ų313.2 Ų13.22%0.0218%0.077CC..THydrogen-bonded Turntrans-54.3-30.5178.256.80000112.7V144 R153 Q209 P399V144-S146 PolarHBondContact O-N 2.74Å; S146-R153 PolarHBondContact O-NH2 3.49Å; S146-R153 VanDerWaalsContact O-NH2 3.11Å; S146-Q209 PolarHBondContact OG-OE1 3.33Å; S146-P399 WeakPolarHBondContact O-CB 3.33Å; S146-P399 WeakPolarHBondContact O-CG 3.45Å
147Y93.5Very high96.4Very high16 Ų1610.6 Ų10.66%0.0636%0.056CC..THydrogen-bonded Turntrans-83.40.7177.459.7-97.5000115.8P145 T149 S206 G207 Q209 F227 Y400P145-Y147 HydrophobicContact CB-CD1 3.81Å; P145-Y147 HydrophobicContact CB-CD2 4.22Å; P145-Y147 HydrophobicContact CB-CE1 3.52Å; P145-Y147 HydrophobicContact CB-CE2 3.96Å; P145-Y147 HydrophobicContact CB-CG 4.15Å; P145-Y147 HydrophobicContact CG-CE1 4.48Å; P145-Y147 PolarHBondContact O-N 3.02Å; P145-Y147 VanDerWaalsContact O-N 3.09Å; Y147-T149 PolarHBondContact O-N 2.91Å; Y147-S206 PolarHBondContact OH-O 3.37Å; Y147-G207 WeakPolarHBondContact OH-CA 3.37Å; Y147-Q209 HydrophobicContact CD1-CG 3.97Å; Y147-Q209 HydrophobicContact CE1-CG 3.81Å; Y147-F227 HydrophobicContact CD1-CB 3.77Å; Y147-F227 HydrophobicContact CD1-CD1 4.42Å; Y147-F227 HydrophobicContact CD1-CD2 4.16Å; Y147-F227 AromaticContact CD1-CG 3.86Å; Y147-F227 HydrophobicContact CD1-CG 3.86Å; Y147-F227 HydrophobicContact CE1-CB 4.45Å; Y147-F227 HydrophobicContact CG-CB 4.49Å; Y147-F227 HydrophobicContact CG-CD2 4.06Å; Y147-F227 HydrophobicContact CG-CE2 4.46Å; Y147-F227 HydrophobicContact CG-CG 4.11Å; Y147-Y400 WeakPolarHBondContact O-CE2 3.44Å; Y147-Y400 PolarHBondContact O-OH 3.42Å; Y147-Y400 VanDerWaalsContact O-OH 3.07Å
148Y95.3Very high96.6Very high4 Ų410.6 Ų10.62%0.0166%0.056CC..  trans-62.5128.9172.9-88.715.4000110.8F10 K68 V144 P145 E152 R153 V156F10-Y148 HydrophobicContact CZ-CE1 4.36Å; K68-Y148 WeakPolarHBondContact CE-OH 3.44Å; K68-Y148 PolarHBondContact O-OH 3.39Å; V144-Y148 HydrophobicContact CB-CD2 3.82Å; V144-Y148 HydrophobicContact CB-CE2 4.39Å; V144-Y148 HydrophobicContact CB-CG 4.38Å; V144-Y148 HydrophobicContact CG1-CD2 3.9Å; V144-Y148 HydrophobicContact CG1-CE2 4.24Å; P145-Y148 HydrophobicContact CB-CD1 3.94Å; P145-Y148 HydrophobicContact CB-CE1 4.23Å; P145-Y148 HydrophobicContact CG-CD1 3.84Å; P145-Y148 HydrophobicContact CG-CE1 3.65Å; P145-Y148 HydrophobicContact CG-CG 4.45Å; P145-Y148 WeakPolarHBondContact O-CB 3.47Å; P145-Y148 PolarHBondContact O-N 3.47Å; Y148-E152 HydrophobicContact CD1-CB 4.3Å; Y148-E152 HydrophobicContact CD2-CB 3.89Å; Y148-E152 HydrophobicContact CE2-CB 4.45Å; Y148-E152 HydrophobicContact CG-CB 3.81Å; Y148-R153 PolarHBondContact O-NE 2.92Å; Y148-R153 PolarHBondContact O-NH2 3.11Å; Y148-V156 HydrophobicContact CD2-CG2 4.38Å; Y148-V156 HydrophobicContact CE2-CG2 3.94Å
149T95.1Very high96.8Very high3 Ų36.8 Ų6.82%0.0183%0.033CC..  trans-69.4174.5174.260.20000112.3Y147 A151 E152 R153 Y400 Y446 L452 Y454Y147-T149 PolarHBondContact O-N 2.91Å; T149-A151 VanDerWaalsContact C-N 3.33Å; T149-A151 PolarHBondContact O-N 3.19Å; T149-E152 WeakPolarHBondContact CB-OE2 3.44Å; T149-E152 WeakPolarHBondContact CG2-OE2 3.44Å; T149-E152 PolarHBondContact N-OE2 2.93Å; T149-E152 PolarHBondContact O-N 3.14Å; T149-E152 PolarHBondContact OG1-N 3.3Å; T149-E152 PolarHBondContact OG1-OE2 3.03Å; T149-R153 WeakPolarHBondContact O-CB 3.4Å; T149-R153 VanDerWaalsContact O-CG 3.26Å; T149-R153 WeakPolarHBondContact O-CG 3.45Å; T149-R153 PolarHBondContact O-N 3.34Å; T149-Y400 HydrophobicContact CG2-CE2 4.09Å; T149-Y446 HydrophobicContact CG2-CE2 4.28Å; T149-L452 HydrophobicContact CG2-CD1 3.7Å; T149-Y454 HydrophobicContact CG2-CD2 4.3Å; T149-Y454 HydrophobicContact CG2-CG 4.17Å
150D95.6Very high96.9Very high6 Ų65.8 Ų5.83%0.0323%0.028CC..Hα-helixtrans-59.7-41.8177.4-167.8-89000112.1R153 R154 Y446 I459 V489 F490D150-R153 PolarHBondContact O-N 3.39Å; D150-R154 WeakPolarHBondContact O-CG 3.46Å; D150-R154 PolarHBondContact O-N 3.44Å; D150-R154 IonicContact OD1-CZ 3.39Å; D150-R154 IonicContact OD1-NE 2.8Å; D150-R154 PolarHBondContact OD1-NE 3.36Å; D150-R154 IonicContact OD1-NH2 3.49Å; D150-R154 PolarHBondContact OD1-NH2 2.92Å; D150-R154 IonicContact OD2-NH2 2.83Å; D150-R154 PolarHBondContact OD2-NH2 3.38Å; D150-Y446 WeakPolarHBondContact CB-OH 3.38Å; D150-Y446 PolarHBondContact N-OH 3.34Å; D150-I459 HydrophobicContact CB-CG1 4.43Å; D150-I459 HydrophobicContact CB-CG2 3.78Å; D150-I459 VanDerWaalsContact CG-CG2 3.44Å; D150-I459 WeakPolarHBondContact OD1-CG2 3.38Å; D150-V489 VanDerWaalsContact OD2-CA 3.24Å; D150-V489 WeakPolarHBondContact OD2-CA 3.39Å; D150-V489 VanDerWaalsContact OD2-CB 3.24Å; D150-V489 WeakPolarHBondContact OD2-CB 3.47Å; D150-F490 PolarHBondContact OD2-N 3.1Å
151A95.4Very high96.9Very high8 Ų810 Ų107%0.0665%0.047CC..Hα-helixtrans-68.3-44.6176.300000112.4T149 R153 R154 S155T149-A151 VanDerWaalsContact C-N 3.33Å; T149-A151 PolarHBondContact O-N 3.19Å; A151-R153 VanDerWaalsContact C-N 3.31Å; A151-R153 PolarHBondContact O-N 3.37Å; A151-R154 PolarHBondContact O-N 3.46Å; A151-S155 WeakPolarHBondContact O-CB 3.49Å; A151-S155 PolarHBondContact O-N 3.16Å
152E96.5Very high96.9Very high7 Ų710.2 Ų10.23%0.0335%0.049CC..Hα-helixtrans-61.5-38.6175.1-77.7158.5145.100111.7H71 R73 Y148 T149 V156H71-E152 HydrophobicContact CB-CG 4.37Å; H71-E152 WeakPolarHBondContact O-CG 3.36Å; R73-E152 IonicContact CZ-OE1 3.15Å; R73-E152 VanDerWaalsContact CZ-OE1 3.28Å; R73-E152 IonicContact NE-OE1 2.75Å; R73-E152 PolarHBondContact NE-OE1 3.07Å; R73-E152 IonicContact NH2-OE1 3.64Å; R73-E152 PolarHBondContact NH2-OE1 3.38Å; Y148-E152 HydrophobicContact CD1-CB 4.3Å; Y148-E152 HydrophobicContact CD2-CB 3.89Å; Y148-E152 HydrophobicContact CE2-CB 4.45Å; Y148-E152 HydrophobicContact CG-CB 3.81Å; T149-E152 WeakPolarHBondContact CB-OE2 3.44Å; T149-E152 WeakPolarHBondContact CG2-OE2 3.44Å; T149-E152 PolarHBondContact N-OE2 2.93Å; T149-E152 PolarHBondContact O-N 3.14Å; T149-E152 PolarHBondContact OG1-N 3.3Å; T149-E152 PolarHBondContact OG1-OE2 3.03Å; E152-V156 WeakPolarHBondContact O-CG2 3.47Å; E152-V156 PolarHBondContact O-N 3.26Å
153R97.4Very high96.9Very high6 Ų610.5 Ų10.52%0.0235%0.051CC..Hα-helixtrans-66.5-45174.7-73.6169.5-170.4-90.2-10.2112.3P145 S146 Y148 T149 D150 A151 S155 V156 M157 L170 N172 H487 V489P145-R153 PolarHBondContact O-NH2 3.19Å; S146-R153 PolarHBondContact O-NH2 3.49Å; S146-R153 VanDerWaalsContact O-NH2 3.11Å; Y148-R153 PolarHBondContact O-NE 2.92Å; Y148-R153 PolarHBondContact O-NH2 3.11Å; T149-R153 WeakPolarHBondContact O-CB 3.4Å; T149-R153 VanDerWaalsContact O-CG 3.26Å; T149-R153 WeakPolarHBondContact O-CG 3.45Å; T149-R153 PolarHBondContact O-N 3.34Å; D150-R153 PolarHBondContact O-N 3.39Å; A151-R153 VanDerWaalsContact C-N 3.31Å; A151-R153 PolarHBondContact O-N 3.37Å; R153-S155 PolarHBondContact O-N 3.5Å; R153-V156 PolarHBondContact O-N 3.03Å; R153-M157 WeakPolarHBondContact O-CG 3.36Å; R153-M157 PolarHBondContact O-N 3.43Å; R153-L170 HydrophobicContact CB-CD1 3.85Å; R153-L170 HydrophobicContact CG-CD1 4.17Å; R153-L170 WeakPolarHBondContact O-CD1 3.48Å; R153-N172 PolarHBondContact NH1-OD1 3.01Å; R153-N172 PolarHBondContact NH2-OD1 3.23Å; R153-H487 WeakPolarHBondContact CD-O 3.38Å; R153-H487 PolarHBondContact NH1-O 3.37Å; R153-V489 HydrophobicContact CB-CG1 3.47Å; R153-V489 VanDerWaalsContact CB-CG1 3.47Å; R153-V489 HydrophobicContact CG-CG1 4.36Å
154R96.9Very high96.9Very high24 Ų2412.3 Ų12.39%0.0917%0.069CC..Hα-helixtrans-60.7-44.7175.7-73177.2-154.9-78.7-12.1111.7D150 A151 V156 M157 D158 F490D150-R154 WeakPolarHBondContact O-CG 3.46Å; D150-R154 PolarHBondContact O-N 3.44Å; D150-R154 IonicContact OD1-CZ 3.39Å; D150-R154 IonicContact OD1-NE 2.8Å; D150-R154 PolarHBondContact OD1-NE 3.36Å; D150-R154 IonicContact OD1-NH2 3.49Å; D150-R154 PolarHBondContact OD1-NH2 2.92Å; D150-R154 IonicContact OD2-NH2 2.83Å; D150-R154 PolarHBondContact OD2-NH2 3.38Å; A151-R154 PolarHBondContact O-N 3.46Å; R154-V156 PolarHBondContact O-N 2.81Å; R154-M157 CarbonylContact O-C 3.54Å; R154-M157 WeakPolarHBondContact O-CA 3.26Å; R154-M157 WeakPolarHBondContact O-CB 3.39Å; R154-M157 PolarHBondContact O-N 3.43Å; R154-D158 PolarHBondContact O-N 3.29Å; R154-F490 PolarHBondContact NH2-O 2.73Å
155S97.7Very high96.9Very high0 Ų012.6 Ų12.60%07%0.071CC..Hα-helixtrans-55.5-34.9175.3179.40000112.9H71 G72 E115 A151 R153 A159H71-S155 PolarHBondContact ND1-OG 2.88Å; G72-S155 VanDerWaalsContact N-CB 3.33Å; G72-S155 PolarHBondContact N-OG 2.94Å; G72-S155 VanDerWaalsContact N-OG 3.08Å; E115-S155 WeakPolarHBondContact OE1-CB 3.32Å; E115-S155 PolarHBondContact OE1-OG 2.95Å; A151-S155 WeakPolarHBondContact O-CB 3.49Å; A151-S155 PolarHBondContact O-N 3.16Å; R153-S155 PolarHBondContact O-N 3.5Å; S155-A159 WeakPolarHBondContact O-CB 3.43Å; S155-A159 PolarHBondContact O-N 3.31Å; S155-A159 VanDerWaalsContact O-N 3.09Å
156V98.3Very high96.9Very high0 Ų016.4 Ų16.40%09%0.091CC..Hα-helixtrans-75.8-34.5171.7-179.90000112.9L8 I142 V144 Y148 E152 R153 R154 A159 A160 L170L8-V156 HydrophobicContact CD2-CG1 4.26Å; I142-V156 HydrophobicContact CG2-CG1 3.99Å; V144-V156 HydrophobicContact CG1-CB 4.34Å; V144-V156 HydrophobicContact CG1-CG1 4.09Å; V144-V156 HydrophobicContact CG1-CG2 4.17Å; Y148-V156 HydrophobicContact CD2-CG2 4.38Å; Y148-V156 HydrophobicContact CE2-CG2 3.94Å; E152-V156 WeakPolarHBondContact O-CG2 3.47Å; E152-V156 PolarHBondContact O-N 3.26Å; R153-V156 PolarHBondContact O-N 3.03Å; R154-V156 PolarHBondContact O-N 2.81Å; V156-A159 PolarHBondContact O-N 3.01Å; V156-A160 PolarHBondContact O-N 3.42Å; V156-L170 HydrophobicContact CB-CD1 4.42Å; V156-L170 HydrophobicContact CB-CD2 4.42Å; V156-L170 HydrophobicContact CG1-CD2 3.77Å
157M98Very high97.1Very high42 Ų4216.9 Ų16.921%0.20710%0.095CC..Hα-helixtrans-67.8-37.2174-66.1-178.964.500112.4R153 R154 A160 Q161 L170 H487R153-M157 WeakPolarHBondContact O-CG 3.36Å; R153-M157 PolarHBondContact O-N 3.43Å; R154-M157 CarbonylContact O-C 3.54Å; R154-M157 WeakPolarHBondContact O-CA 3.26Å; R154-M157 WeakPolarHBondContact O-CB 3.39Å; R154-M157 PolarHBondContact O-N 3.43Å; M157-A160 PolarHBondContact O-N 3Å; M157-Q161 WeakPolarHBondContact O-CG 3.43Å; M157-Q161 PolarHBondContact O-N 2.91Å; M157-Q161 VanDerWaalsContact O-N 3.14Å; M157-Q161 PolarHBondContact O-NE2 3.29Å; M157-Q161 VanDerWaalsContact O-NE2 3.1Å; M157-L170 HydrophobicContact CG-CD1 3.68Å; M157-L170 HydrophobicContact CG-CG 4Å; M157-L170 HydrophobicContact SD-CD1 4.32Å; M157-H487 HydrophobicContact SD-CB 4.01Å
158D98Very high97.2Very high2 Ų218 Ų181%0.01110%0.101CC..Hα-helixtrans-69-42.3175.7-66.3-15.3000109.8E115 R154 A160 Q161 I162 L588 L593E115-D158 HydrophobicContact CG-CB 4.29Å; R154-D158 PolarHBondContact O-N 3.29Å; D158-A160 VanDerWaalsContact C-N 3.31Å; D158-A160 PolarHBondContact O-N 3.09Å; D158-Q161 PolarHBondContact O-N 3.38Å; D158-Q161 VanDerWaalsContact O-N 3.16Å; D158-Q161 PolarHBondContact OD1-NE2 2.83Å; D158-I162 WeakPolarHBondContact O-CG1 3.33Å; D158-I162 PolarHBondContact O-N 3.07Å; D158-L588 HydrophobicContact CB-CD1 4.26Å; D158-L588 PolarHBondContact OD2-N 2.89Å; D158-L593 HydrophobicContact CB-CD1 4.07Å
159A98.5Very high97.3Very high0 Ų018.6 Ų18.60%010%0.104CC..Hα-helixtrans-58.5-37.3170.900000113.8E115 T118 G119 L122 S155 V156 I162 A163E115-A159 HydrophobicContact CB-CB 4.43Å; E115-A159 VanDerWaalsContact O-CB 3.3Å; E115-A159 WeakPolarHBondContact O-CB 3.48Å; T118-A159 HydrophobicContact CG2-CB 3.68Å; G119-A159 WeakPolarHBondContact CA-O 3.31Å; L122-A159 HydrophobicContact CD1-CB 4.16Å; S155-A159 WeakPolarHBondContact O-CB 3.43Å; S155-A159 PolarHBondContact O-N 3.31Å; S155-A159 VanDerWaalsContact O-N 3.09Å; V156-A159 PolarHBondContact O-N 3.01Å; A159-I162 PolarHBondContact O-N 2.65Å; A159-A163 PolarHBondContact O-N 2.97Å
160A98.4Very high97.4Very high0 Ų018.5 Ų18.50%010%0.103CC..Hα-helixtrans-66.6-40.4175.300000112.1L122 I142 V156 M157 D158 A163 G164 L165 C167L122-A160 HydrophobicContact CD1-CB 4.29Å; I142-A160 HydrophobicContact CD1-CB 3.73Å; V156-A160 PolarHBondContact O-N 3.42Å; M157-A160 PolarHBondContact O-N 3Å; D158-A160 VanDerWaalsContact C-N 3.31Å; D158-A160 PolarHBondContact O-N 3.09Å; A160-A163 PolarHBondContact O-N 3.24Å; A160-G164 PolarHBondContact O-N 3.17Å; A160-L165 CarbonylContact C-O 3.53Å; A160-L165 HydrophobicContact CB-CB 4.42Å; A160-L165 WeakPolarHBondContact O-CB 3.36Å; A160-L165 PolarHBondContact O-N 3.29Å; A160-C167 HydrophobicContact CB-CB 4.05Å
161Q98.1Very high97.5Very high89 Ų8918.2 Ų18.242%0.41610%0.102SC..Hα-helixtrans-63.2-41.3174.5-71.8167.296.700111.5M157 D158 A163 G164 L593M157-Q161 WeakPolarHBondContact O-CG 3.43Å; M157-Q161 PolarHBondContact O-N 2.91Å; M157-Q161 VanDerWaalsContact O-N 3.14Å; M157-Q161 PolarHBondContact O-NE2 3.29Å; M157-Q161 VanDerWaalsContact O-NE2 3.1Å; D158-Q161 PolarHBondContact O-N 3.38Å; D158-Q161 VanDerWaalsContact O-N 3.16Å; D158-Q161 PolarHBondContact OD1-NE2 2.83Å; Q161-A163 VanDerWaalsContact C-N 3.31Å; Q161-A163 PolarHBondContact O-N 3.37Å; Q161-G164 WeakPolarHBondContact O-CA 3.29Å; Q161-G164 PolarHBondContact O-N 3.07Å; Q161-L593 HydrophobicContact CB-CD1 4.32Å; Q161-L593 HydrophobicContact CB-CD2 4.33Å
162I98.6Very high97.6Very high5 Ų518.2 Ų18.23%0.02610%0.1CC..Hα-helixtrans-56.3-43.1174.7-66.3166.8000111.6E115 Q116 D158 A159 G164 L593 F596 E600E115-I162 HydrophobicContact CB-CD1 3.88Å; Q116-I162 HydrophobicContact CG-CD1 4.26Å; D158-I162 WeakPolarHBondContact O-CG1 3.33Å; D158-I162 PolarHBondContact O-N 3.07Å; A159-I162 PolarHBondContact O-N 2.65Å; I162-G164 PolarHBondContact O-N 2.59Å; I162-L593 HydrophobicContact CD1-CD1 4.16Å; I162-L593 HydrophobicContact CG1-CD1 3.71Å; I162-F596 HydrophobicContact CD1-CB 3.8Å; I162-F596 HydrophobicContact CD1-CD2 3.9Å; I162-F596 HydrophobicContact CD1-CG 4.37Å; I162-F596 HydrophobicContact CG1-CB 3.86Å; I162-E600 HydrophobicContact CG2-CB 3.75Å; I162-E600 HydrophobicContact CG2-CG 4.04Å; I162-E600 WeakPolarHBondContact O-CG 3.15Å
163A98.2Very high97.6Very high5 Ų518.5 Ų18.54%0.04110%0.102CC..THydrogen-bonded Turntrans-73.10.5175.800000114.7L122 K126 A159 A160 Q161 L165L122-A163 HydrophobicContact CB-CB 3.67Å; K126-A163 PolarHBondContact NZ-O 3.43Å; A159-A163 PolarHBondContact O-N 2.97Å; A160-A163 PolarHBondContact O-N 3.24Å; Q161-A163 VanDerWaalsContact C-N 3.31Å; Q161-A163 PolarHBondContact O-N 3.37Å; A163-L165 HydrophobicContact CB-CD1 4.03Å; A163-L165 HydrophobicContact CB-CG 4.27Å
164G97Very high97.5Very high38 Ų3818.3 Ų18.339%0.39210%0.101SC..THydrogen-bonded Turntrans61.845.2-172.500000112.3K126 A160 Q161 I162K126-G164 PolarHBondContact NZ-O 3.2Å; A160-G164 PolarHBondContact O-N 3.17Å; Q161-G164 WeakPolarHBondContact O-CA 3.29Å; Q161-G164 PolarHBondContact O-N 3.07Å; I162-G164 PolarHBondContact O-N 2.59Å
165L97.9Very high97.6Very high6 Ų617.2 Ų17.23%0.03110%0.097CC..  trans-117.1129.5176.7-70.9167.7000111.1F6 L122 K126 V137 V138 A160 A163 C167F6-L165 HydrophobicContact CD2-CD1 4.49Å; F6-L165 HydrophobicContact CE2-CD1 3.76Å; F6-L165 HydrophobicContact CE2-CD2 4.25Å; F6-L165 HydrophobicContact CZ-CD1 4.48Å; L122-L165 HydrophobicContact CB-CD1 4.11Å; K126-L165 HydrophobicContact CB-CD1 4.47Å; K126-L165 HydrophobicContact CB-CD2 4.32Å; K126-L165 HydrophobicContact CD-CD2 3.83Å; K126-L165 HydrophobicContact CD-CG 4.08Å; K126-L165 HydrophobicContact CG-CD2 4.17Å; V137-L165 HydrophobicContact CG1-CD2 3.97Å; V138-L165 CarbonylContact O-C 3.38Å; V138-L165 WeakPolarHBondContact O-CA 3.44Å; A160-L165 CarbonylContact C-O 3.53Å; A160-L165 HydrophobicContact CB-CB 4.42Å; A160-L165 WeakPolarHBondContact O-CB 3.36Å; A160-L165 PolarHBondContact O-N 3.29Å; A163-L165 HydrophobicContact CB-CD1 4.03Å; A163-L165 HydrophobicContact CB-CG 4.27Å; L165-C167 PolarHBondContact O-N 2.53Å
166N96.5Very high97.6Very high80 Ų8017.2 Ų17.243%0.42810%0.097SC..EExtended strand (participates in β ladder)trans-80.698.7167.1-179.628.6000109.4V138 D139 C140 L168V138-N166 HydrophobicContact CG1-CB 4.2Å; V138-N166 PolarHBondContact O-N 3.08Å; D139-N166 WeakPolarHBondContact CA-O 3.47Å; D139-N166 PolarHBondContact OD1-ND2 3.37Å; C140-N166 PolarHBondContact N-O 3.31Å; N166-L168 WeakPolarHBondContact ND2-CD2 3.47Å; N166-L168 PolarHBondContact O-N 2.66Å; N166-L168 VanDerWaalsContact O-N 3.08Å
167C97.2Very high97.5Very high14 Ų1417.2 Ų17.210%0.09510%0.097CC..EExtended strand (participates in β ladder)trans-72.998.6175.2-174.60000110.1I142 A160 L165 R169 L170 H487I142-C167 HydrophobicContact CD1-CB 4.39Å; A160-C167 HydrophobicContact CB-CB 4.05Å; L165-C167 PolarHBondContact O-N 2.53Å; C167-R169 VanDerWaalsContact C-N 3.26Å; C167-R169 PolarHBondContact O-N 3.06Å; C167-R169 VanDerWaalsContact SG-C 3.54Å; C167-R169 PolarHBondContact SG-O 3.1Å; C167-R169 VanDerWaalsContact SG-O 3.38Å; C167-L170 VanDerWaalsContact SG-CD2 3.6Å; C167-H487 PolarHBondContact O-CE1 2.61Å
168L96.9Very high97.5Very high39 Ų3915.2 Ų15.220%0.2049%0.087CC..EExtended strand (participates in β ladder)trans-65.2-31178.8-62.3-178.1000112.5D139 C140 V141 N166 L383D139-L168 HydrophobicContact CB-CD1 3.96Å; D139-L168 HydrophobicContact CB-CD2 4.32Å; D139-L168 HydrophobicContact CB-CG 4.06Å; C140-L168 PolarHBondContact O-N 2.99Å; V141-L168 HydrophobicContact CG2-CB 4.34Å; N166-L168 WeakPolarHBondContact ND2-CD2 3.47Å; N166-L168 PolarHBondContact O-N 2.66Å; N166-L168 VanDerWaalsContact O-N 3.08Å; L168-L383 HydrophobicContact CB-CD1 3.91Å; L168-L383 HydrophobicContact CD1-CB 3.99Å
169R97.4Very high97.5Very high17 Ų1715.1 Ų15.16%0.0649%0.087CC..EExtended strand (participates in β ladder)trans-159136.7176.2-177.7163.5-175.5-163.9-3.1110.2V141 I142 C167 L383 D396 V486V141-R169 WeakPolarHBondContact CA-O 3.44Å; V141-R169 HydrophobicContact CG1-CB 4.4Å; V141-R169 WeakPolarHBondContact CG1-O 3.48Å; V141-R169 HydrophobicContact CG2-CB 4.18Å; I142-R169 PolarHBondContact N-O 2.81Å; C167-R169 VanDerWaalsContact C-N 3.26Å; C167-R169 PolarHBondContact O-N 3.06Å; C167-R169 VanDerWaalsContact SG-C 3.54Å; C167-R169 PolarHBondContact SG-O 3.1Å; C167-R169 VanDerWaalsContact SG-O 3.38Å; R169-L383 HydrophobicContact CB-CD1 3.96Å; R169-D396 IonicContact NH2-OD2 3.17Å; R169-D396 PolarHBondContact NH2-OD2 2.73Å; R169-V486 WeakPolarHBondContact CG-O 3.38Å; R169-V486 PolarHBondContact NE-O 2.66Å
170L97.8Very high97.3Very high1 Ų115.4 Ų15.41%0.0059%0.089CC..EExtended strand (participates in β ladder)trans-83.7128.2154.5-66.6-175.5000108.1I142 V144 R153 V156 M157 C167 H487I142-L170 HydrophobicContact CB-CD2 3.97Å; I142-L170 HydrophobicContact CG2-CD2 4.26Å; I142-L170 WeakPolarHBondContact O-CA 3.4Å; V144-L170 HydrophobicContact CG1-CD1 4.28Å; V144-L170 HydrophobicContact CG1-CD2 4.18Å; V144-L170 HydrophobicContact CG2-CB 4.2Å; R153-L170 HydrophobicContact CB-CD1 3.85Å; R153-L170 HydrophobicContact CG-CD1 4.17Å; R153-L170 WeakPolarHBondContact O-CD1 3.48Å; V156-L170 HydrophobicContact CB-CD1 4.42Å; V156-L170 HydrophobicContact CB-CD2 4.42Å; V156-L170 HydrophobicContact CG1-CD2 3.77Å; M157-L170 HydrophobicContact CG-CD1 3.68Å; M157-L170 HydrophobicContact CG-CG 4Å; M157-L170 HydrophobicContact SD-CD1 4.32Å; C167-L170 VanDerWaalsContact SG-CD2 3.6Å; L170-H487 HydrophobicContact CB-CB 3.97Å; L170-H487 HydrophobicContact CD1-CB 4.4Å; L170-H487 HydrophobicContact CG-CB 4.2Å; L170-H487 PolarHBondContact N-ND1 3.12Å
171M96.8Very high97.2Very high0 Ų015.7 Ų15.70%09%0.09CC..EExtended strand (participates in β ladder)trans-117.4131.2-174.3-164170.6-165.300110.3V141 I142 S143 V144 E173 T175 A176 L179 Q379 I394V141-M171 HydrophobicContact CG1-CB 3.89Å; V141-M171 HydrophobicContact CG1-SD 4.32Å; I142-M171 PolarHBondContact O-N 2.92Å; S143-M171 WeakPolarHBondContact CA-O 3.44Å; V144-M171 PolarHBondContact N-O 2.79Å; M171-E173 PolarHBondContact O-N 3.45Å; M171-T175 HydrophobicContact CE-CG2 4.08Å; M171-A176 HydrophobicContact CE-CB 4.33Å; M171-A176 HydrophobicContact CG-CB 4.08Å; M171-A176 HydrophobicContact SD-CB 3.74Å; M171-L179 HydrophobicContact CE-CB 4.08Å; M171-L179 HydrophobicContact CE-CD2 3.85Å; M171-Q379 HydrophobicContact CE-CB 4Å; M171-Q379 HydrophobicContact CE-CG 4.2Å; M171-Q379 HydrophobicContact SD-CB 3.56Å; M171-Q379 VanDerWaalsContact SD-CB 3.56Å; M171-Q379 HydrophobicContact SD-CG 3.8Å; M171-I394 HydrophobicContact CE-CD1 4.49Å
172N97.7Very high97.1Very high8 Ų811.4 Ų11.44%0.0437%0.07CC..EExtended strand (participates in β ladder)trans-61.2127.5173.5-68.2-23.6000109.2V144 R153 T174 T175 A176 D396V144-N172 CarbonylContact O-C 3.43Å; V144-N172 WeakPolarHBondContact O-CA 3.46Å; R153-N172 PolarHBondContact NH1-OD1 3.01Å; R153-N172 PolarHBondContact NH2-OD1 3.23Å; N172-T174 VanDerWaalsContact C-N 3.33Å; N172-T174 PolarHBondContact O-N 3.29Å; N172-T175 CarbonylContact O-C 3.54Å; N172-T175 WeakPolarHBondContact O-CA 3.45Å; N172-T175 WeakPolarHBondContact O-CB 3.39Å; N172-T175 PolarHBondContact O-N 2.85Å; N172-A176 PolarHBondContact O-N 3.39Å; N172-D396 PolarHBondContact ND2-OD1 3.45Å; N172-D396 PolarHBondContact ND2-OD2 3.16Å
173E96.6Very high96.7Very high13 Ų1311.8 Ų11.86%0.0617%0.072CC..Hα-helixtrans-48-51.2-176-75.8155.2-176.900112.1V144 P145 M171 T175 A176 V177 Q209 V372V144-E173 VanDerWaalsContact C-CD 3.47Å; V144-E173 WeakPolarHBondContact O-CG 3.46Å; V144-E173 PolarHBondContact O-N 2.81Å; P145-E173 VanDerWaalsContact CA-OE2 3.28Å; P145-E173 WeakPolarHBondContact CA-OE2 3.49Å; P145-E173 WeakPolarHBondContact CD-OE1 3.44Å; P145-E173 WeakPolarHBondContact CG-OE1 3.43Å; M171-E173 PolarHBondContact O-N 3.45Å; E173-T175 VanDerWaalsContact C-N 3.29Å; E173-T175 PolarHBondContact O-N 2.93Å; E173-A176 WeakPolarHBondContact O-CB 3.43Å; E173-A176 PolarHBondContact O-N 3Å; E173-A176 VanDerWaalsContact O-N 3.16Å; E173-V177 WeakPolarHBondContact O-CG2 3.15Å; E173-V177 PolarHBondContact O-N 3.16Å; E173-Q209 PolarHBondContact OE2-NE2 2.92Å; E173-V372 HydrophobicContact CB-CG1 4.32Å; E173-V372 HydrophobicContact CB-CG2 4.45Å; E173-V372 HydrophobicContact CG-CG1 4.11Å
174T95.8Very high96.4Very high2 Ų217.3 Ų17.31%0.0129%0.093CC..Hα-helixtrans-62.4-29.1176.154.20000114.3N172 S178 D202 Q209 S211N172-T174 VanDerWaalsContact C-N 3.33Å; N172-T174 PolarHBondContact O-N 3.29Å; T174-S178 WeakPolarHBondContact O-CB 3.48Å; T174-S178 PolarHBondContact O-N 2.76Å; T174-S178 PolarHBondContact O-OG 3.43Å; T174-D202 HydrophobicContact CG2-CB 4.26Å; T174-Q209 HydrophobicContact CG2-CB 3.71Å; T174-S211 WeakPolarHBondContact CB-OG 3.48Å
175T97.7Very high96.2Very high0 Ų018 Ų180%09%0.085CC..Hα-helixtrans-79.4-31.9176-59.90000111.8M171 N172 E173 S178 L179 I222 I394M171-T175 HydrophobicContact CE-CG2 4.08Å; N172-T175 CarbonylContact O-C 3.54Å; N172-T175 WeakPolarHBondContact O-CA 3.45Å; N172-T175 WeakPolarHBondContact O-CB 3.39Å; N172-T175 PolarHBondContact O-N 2.85Å; E173-T175 VanDerWaalsContact C-N 3.29Å; E173-T175 PolarHBondContact O-N 2.93Å; T175-S178 PolarHBondContact O-N 3.48Å; T175-L179 PolarHBondContact O-N 3.17Å; T175-I222 HydrophobicContact CG2-CD1 4.17Å; T175-I222 HydrophobicContact CG2-CG1 4.28Å; T175-I222 WeakPolarHBondContact OG1-CD1 3.07Å; T175-I394 HydrophobicContact CG2-CG2 3.94Å
176A97.9Very high95.9Very high0 Ų024.1 Ų24.10%011%0.113CC..Hα-helixtrans-63.7-46.4170.200000110.8M171 N172 E173 S178 L179 A180 V372 G375M171-A176 HydrophobicContact CE-CB 4.33Å; M171-A176 HydrophobicContact CG-CB 4.08Å; M171-A176 HydrophobicContact SD-CB 3.74Å; N172-A176 PolarHBondContact O-N 3.39Å; E173-A176 WeakPolarHBondContact O-CB 3.43Å; E173-A176 PolarHBondContact O-N 3Å; E173-A176 VanDerWaalsContact O-N 3.16Å; A176-S178 VanDerWaalsContact C-N 3.33Å; A176-S178 PolarHBondContact O-N 3.49Å; A176-L179 PolarHBondContact O-N 3.39Å; A176-A180 PolarHBondContact O-N 2.76Å; A176-V372 HydrophobicContact CB-CG1 4.18Å; A176-V372 WeakPolarHBondContact CB-O 3.39Å; A176-G375 VanDerWaalsContact O-CA 3.25Å; A176-G375 WeakPolarHBondContact O-CA 3.48Å
177V97.4Very high95.8Very high0 Ų024.4 Ų24.40%012%0.115CC..Hα-helixtrans-57.9-44.7172.51750000111.1E173 L179 A180 Y181 F200 V341 L366 A371 V372E173-V177 WeakPolarHBondContact O-CG2 3.15Å; E173-V177 PolarHBondContact O-N 3.16Å; V177-L179 VanDerWaalsContact C-N 3.35Å; V177-L179 PolarHBondContact O-N 3.07Å; V177-A180 PolarHBondContact O-N 2.76Å; V177-Y181 PolarHBondContact O-N 3.28Å; V177-F200 HydrophobicContact CG1-CD1 3.63Å; V177-F200 HydrophobicContact CG1-CE1 4.12Å; V177-F200 HydrophobicContact CG1-CG 4.27Å; V177-V341 HydrophobicContact CG1-CG1 3.8Å; V177-V341 HydrophobicContact CG1-CG2 4.11Å; V177-V341 HydrophobicContact CG2-CG2 4.16Å; V177-L366 HydrophobicContact CG1-CD1 3.49Å; V177-L366 VanDerWaalsContact CG1-CD1 3.49Å; V177-A371 HydrophobicContact CG1-CB 4.34Å; V177-A371 HydrophobicContact CG2-CB 3.99Å; V177-V372 HydrophobicContact CG2-CB 4.47Å; V177-V372 HydrophobicContact CG2-CG2 3.59Å
178S97.5Very high95.7Very high0 Ų024.4 Ų24.40%011%0.114CC..Hα-helixtrans-62-37.7177-60.90000113.2T174 T175 A176 G182 F200 C213 F215T174-S178 WeakPolarHBondContact O-CB 3.48Å; T174-S178 PolarHBondContact O-N 2.76Å; T174-S178 PolarHBondContact O-OG 3.43Å; T175-S178 PolarHBondContact O-N 3.48Å; A176-S178 VanDerWaalsContact C-N 3.33Å; A176-S178 PolarHBondContact O-N 3.49Å; S178-G182 PolarHBondContact O-N 2.96Å; S178-F200 WeakPolarHBondContact OG-CD2 3.34Å; S178-F200 VanDerWaalsContact OG-CE2 3.26Å; S178-F200 WeakPolarHBondContact OG-CE2 3.44Å; S178-C213 PolarHBondContact OG-SG 3.25Å; S178-F215 VanDerWaalsContact O-CE1 3.31Å; S178-F215 WeakPolarHBondContact O-CE1 3.43Å; S178-F215 WeakPolarHBondContact O-CZ 3.5Å
179L96.9Very high95.7Very high0 Ų023.6 Ų23.60%011%0.111CC..Hα-helixtrans-67.3-46.2173.2174.759.8000111.5M171 T175 A176 V177 Y181 G182 I183 L378 Q379 I382 F392 I394M171-L179 HydrophobicContact CE-CB 4.08Å; M171-L179 HydrophobicContact CE-CD2 3.85Å; T175-L179 PolarHBondContact O-N 3.17Å; A176-L179 PolarHBondContact O-N 3.39Å; V177-L179 VanDerWaalsContact C-N 3.35Å; V177-L179 PolarHBondContact O-N 3.07Å; L179-Y181 PolarHBondContact O-N 3.04Å; L179-G182 PolarHBondContact O-N 2.9Å; L179-I183 HydrophobicContact CD1-CB 4.28Å; L179-I183 HydrophobicContact CD1-CD1 4.48Å; L179-I183 WeakPolarHBondContact O-CG2 3.36Å; L179-I183 PolarHBondContact O-N 3.34Å; L179-I183 VanDerWaalsContact O-N 3.13Å; L179-L378 HydrophobicContact CD2-CB 3.76Å; L179-L378 HydrophobicContact CG-CB 4.13Å; L179-L378 HydrophobicContact CG-CD1 4.39Å; L179-Q379 HydrophobicContact CD2-CB 3.92Å; L179-I382 HydrophobicContact CD1-CD1 4.17Å; L179-I382 HydrophobicContact CD2-CD1 4.09Å; L179-F392 HydrophobicContact CD1-CD1 3.34Å; L179-F392 HydrophobicContact CD1-CE1 3.63Å; L179-F392 HydrophobicContact CD1-CG 4.16Å; L179-I394 HydrophobicContact CD1-CD1 3.84Å; L179-I394 HydrophobicContact CD1-CG1 4.28Å; L179-I394 HydrophobicContact CD2-CD1 3.77Å; L179-I394 HydrophobicContact CG-CD1 4.27Å
180A95.6Very high95.6Very high7 Ų724.7 Ų24.76%0.05812%0.124CC..Hα-helixtrans-60-30177.300000112.4A176 V177 Y184 L378A176-A180 PolarHBondContact O-N 2.76Å; V177-A180 PolarHBondContact O-N 2.76Å; A180-Y184 VanDerWaalsContact O-CD2 3.27Å; A180-Y184 WeakPolarHBondContact O-CD2 3.31Å; A180-L378 HydrophobicContact CB-CD1 4.29Å
181Y96.1Very high95.4Very high5 Ų527.6 Ų27.62%0.0214%0.143CC..Hα-helixtrans-71-60.8167.4-172.7-97.1000112.4V177 L179 I183 K185 V198 F200 F215 E339 T365 L366V177-Y181 PolarHBondContact O-N 3.28Å; L179-Y181 PolarHBondContact O-N 3.04Å; Y181-I183 PolarHBondContact O-N 2.74Å; Y181-K185 HydrophobicContact CD1-CG 4.2Å; Y181-K185 HydrophobicContact CE1-CG 4.01Å; Y181-K185 WeakPolarHBondContact O-CG 3.13Å; Y181-V198 HydrophobicContact CE1-CG2 3.98Å; Y181-F200 AromaticContact CD1-CZ 3.93Å; Y181-F200 HydrophobicContact CD1-CZ 3.93Å; Y181-F200 HydrophobicContact CD2-CE1 4.09Å; Y181-F200 HydrophobicContact CD2-CZ 4.17Å; Y181-F200 AromaticContact CG-CE1 3.99Å; Y181-F200 HydrophobicContact CG-CE1 3.99Å; Y181-F200 AromaticContact CG-CZ 3.67Å; Y181-F200 HydrophobicContact CG-CZ 3.67Å; Y181-F215 HydrophobicContact CD1-CE1 4.2Å; Y181-F215 HydrophobicContact CD1-CE2 4.02Å; Y181-F215 AromaticContact CD1-CZ 3.8Å; Y181-F215 HydrophobicContact CD1-CZ 3.8Å; Y181-F215 HydrophobicContact CE1-CE2 4.36Å; Y181-E339 HydrophobicContact CD2-CG 4.16Å; Y181-E339 VanDerWaalsContact CE2-CD 3.47Å; Y181-E339 HydrophobicContact CE2-CG 3.77Å; Y181-E339 WeakPolarHBondContact CE2-OE1 3.35Å; Y181-T365 WeakPolarHBondContact CE2-OG1 3.5Å; Y181-L366 HydrophobicContact CD2-CD1 4.48Å; Y181-L366 HydrophobicContact CD2-CD2 4.36Å; Y181-L366 HydrophobicContact CD2-CG 4.38Å
182G95Very high95.1Very high0 Ų036.2 Ų36.20%018%0.183CC..Hα-helixtrans-66.3-35.5-163.500000115.1S178 L179 Y184 L188 F215S178-G182 PolarHBondContact O-N 2.96Å; L179-G182 PolarHBondContact O-N 2.9Å; G182-Y184 VanDerWaalsContact C-N 3.33Å; G182-Y184 PolarHBondContact O-N 2.95Å; G182-L188 WeakPolarHBondContact O-CD1 3.33Å; G182-F215 VanDerWaalsContact CA-CE1 3.49Å
183I91.4Very high95Very high13 Ų1341.4 Ų41.47%0.06721%0.207CC..THydrogen-bonded Turntrans-71.3-28.9-171.8-158.3166.6000113.3L179 Y181 L378 R390 F392L179-I183 HydrophobicContact CD1-CB 4.28Å; L179-I183 HydrophobicContact CD1-CD1 4.48Å; L179-I183 WeakPolarHBondContact O-CG2 3.36Å; L179-I183 PolarHBondContact O-N 3.34Å; L179-I183 VanDerWaalsContact O-N 3.13Å; Y181-I183 PolarHBondContact O-N 2.74Å; I183-L378 HydrophobicContact CD1-CD2 4.38Å; I183-L378 HydrophobicContact CG2-CD1 3.75Å; I183-L378 HydrophobicContact CG2-CD2 4.06Å; I183-R390 HydrophobicContact CG1-CB 4.44Å; I183-R390 PolarHBondContact O-NH1 3.01Å; I183-F392 HydrophobicContact CB-CD2 4.19Å; I183-F392 HydrophobicContact CB-CE2 4.48Å; I183-F392 HydrophobicContact CB-CG 4.36Å; I183-F392 HydrophobicContact CD1-CB 3.99Å; I183-F392 HydrophobicContact CD1-CG 4.39Å; I183-F392 HydrophobicContact CG1-CB 4.17Å; I183-F392 HydrophobicContact CG1-CD2 4.08Å; I183-F392 HydrophobicContact CG1-CG 4.17Å
184Y91.2Very high95Very high120 Ų12050 Ų5047%0.47124%0.244SC..THydrogen-bonded Turntrans-90.1-20-179.6-62.5-57.4000113.8A180 G182 Q186 L378A180-Y184 VanDerWaalsContact O-CD2 3.27Å; A180-Y184 WeakPolarHBondContact O-CD2 3.31Å; G182-Y184 VanDerWaalsContact C-N 3.33Å; G182-Y184 PolarHBondContact O-N 2.95Å; Y184-Q186 PolarHBondContact O-N 3.22Å; Y184-L378 HydrophobicContact CE2-CD1 4.08Å
185K92.6Very high95Very high54 Ų5452.4 Ų52.424%0.23526%0.26CS..  trans-67.3132.8172.9-64-64.1-176.9-175.50109.9Y181 L188 R390Y181-K185 HydrophobicContact CD1-CG 4.2Å; Y181-K185 HydrophobicContact CE1-CG 4.01Å; Y181-K185 WeakPolarHBondContact O-CG 3.13Å; K185-L188 HydrophobicContact CB-CD1 4.14Å; K185-L188 HydrophobicContact CB-CD2 3.83Å; K185-L188 HydrophobicContact CB-CG 3.71Å; K185-L188 HydrophobicContact CG-CD2 4.38Å; K185-R390 PolarHBondContact O-NH1 2.74Å
186Q91.1Very high95.1Very high133 Ų13354 Ų5462%0.62127%0.266SS*.SBendtrans-104.7-20.1-179.9-56.3-58.4-9.900112.6Y184 L188 R390Y184-Q186 PolarHBondContact O-N 3.22Å; Q186-L188 VanDerWaalsContact C-N 3.34Å; Q186-R390 VanDerWaalsContact OE1-CZ 3.29Å
187D94.4Very high95.1Very high87 Ų8754.8 Ų54.847%0.46527%0.27SS..  trans-92.718.1-176.865.8-53.1000113.2R196D187-R196 PolarHBondContact O-NH2 2.9Å; D187-R196 IonicContact OD1-NH1 3.94Å; D187-R196 IonicContact OD2-CZ 3.61Å; D187-R196 IonicContact OD2-NH1 2.67Å; D187-R196 PolarHBondContact OD2-NH1 3.48Å; D187-R196 IonicContact OD2-NH2 2.64Å; D187-R196 PolarHBondContact OD2-NH2 3.31Å
188L95.9Very high95.1Very high13 Ų1354.8 Ų54.87%0.06827%0.27CS..PPolyproline II helixtrans-70.8140.7176.8-64-177.9000110.9G182 K185 Q186 F215G182-L188 WeakPolarHBondContact O-CD1 3.33Å; K185-L188 HydrophobicContact CB-CD1 4.14Å; K185-L188 HydrophobicContact CB-CD2 3.83Å; K185-L188 HydrophobicContact CB-CG 3.71Å; K185-L188 HydrophobicContact CG-CD2 4.38Å; Q186-L188 VanDerWaalsContact C-N 3.34Å; L188-F215 HydrophobicContact CD1-CB 4.24Å; L188-F215 HydrophobicContact CD1-CD1 4.37Å; L188-F215 HydrophobicContact CD2-CB 3.93Å
189P96.9Very high95.2Very high22 Ų2254.8 Ų54.814%0.14327%0.27CS..PPolyproline II helixtrans-53.6150.4177.8-26.134.6000113E193 R196 N216 K217P189-E193 VanDerWaalsContact CA-OE2 3.24Å; P189-E193 WeakPolarHBondContact CA-OE2 3.44Å; P189-E193 HydrophobicContact CB-CB 3.78Å; P189-E193 WeakPolarHBondContact CB-OE2 3.45Å; P189-R196 HydrophobicContact CG-CB 4.08Å; P189-N216 CarbonylContact O-C 3.59Å; P189-N216 VanDerWaalsContact O-CA 3.32Å; P189-N216 WeakPolarHBondContact O-CA 3.23Å; P189-N216 WeakPolarHBondContact O-CB 3.49Å; P189-K217 PolarHBondContact O-N 3.43Å
190A95.6Very high95.3Very high40 Ų4054.8 Ų54.833%0.33127%0.27SS..PPolyproline II helixtrans-58.3158.7173.800000111.4E192 E193 N216A190-E192 PolarHBondContact O-N 2.94Å; A190-E192 VanDerWaalsContact O-N 3.12Å; A190-E193 HydrophobicContact CB-CB 4.48Å; A190-E193 HydrophobicContact CB-CG 3.99Å; A190-E193 PolarHBondContact N-OE2 2.84Å; A190-E193 PolarHBondContact O-N 2.93Å; A190-N216 PolarHBondContact O-ND2 3.26Å
191P92.4Very high95.4Very high63 Ų6354.5 Ų54.541%0.40927%0.267SS..THydrogen-bonded Turntrans-56.3-29.4-177.2-28.637.5000115.3
192E91.4Very high95.5Very high181 Ų18154.8 Ų54.885%0.84627%0.269SS*.THydrogen-bonded Turntrans-93.2-7.3-179.9-41.6-45.7139.800113.6A190A190-E192 PolarHBondContact O-N 2.94Å; A190-E192 VanDerWaalsContact O-N 3.12Å
193E95.9Very high95.6Very high116 Ų11654.8 Ų54.854%0.54227%0.269SS..SBendtrans-82.9162175.8-71.8175.8160.600111.3P189 A190 N216P189-E193 VanDerWaalsContact CA-OE2 3.24Å; P189-E193 WeakPolarHBondContact CA-OE2 3.44Å; P189-E193 HydrophobicContact CB-CB 3.78Å; P189-E193 WeakPolarHBondContact CB-OE2 3.45Å; A190-E193 HydrophobicContact CB-CB 4.48Å; A190-E193 HydrophobicContact CB-CG 3.99Å; A190-E193 PolarHBondContact N-OE2 2.84Å; A190-E193 PolarHBondContact O-N 2.93Å; E193-N216 PolarHBondContact O-ND2 2.84Å
194K95.8Very high95.8Very high193 Ų19355.2 Ų55.284%0.83928%0.277SS*.PPolyproline II helixtrans-57.1127173.5-72.5-174.8177.3-178.50109.7
195P97.3Very high96Very high53 Ų5351.4 Ų51.434%0.34426%0.263SS..PPolyproline II helixtrans-64.5144.6-177.925.7-34.4000111.2I197 A214 F215P195-I197 HydrophobicContact CB-CD1 4.42Å; P195-I197 HydrophobicContact CG-CD1 4.14Å; P195-I197 PolarHBondContact O-N 2.91Å; P195-A214 HydrophobicContact CB-CB 3.8Å; P195-A214 HydrophobicContact CG-CB 4.1Å; P195-F215 CarbonylContact C-O 3.55Å; P195-F215 WeakPolarHBondContact CA-O 3.37Å
196R97.9Very high96Very high34 Ų3449.3 Ų49.313%0.12826%0.255CS..EExtended strand (participates in β ladder)trans-73.1117.4169.9-177.3-178.6-72-173.9-0.8108.7D187 P189 V198 F215 Y336D187-R196 PolarHBondContact O-NH2 2.9Å; D187-R196 IonicContact OD1-NH1 3.94Å; D187-R196 IonicContact OD2-CZ 3.61Å; D187-R196 IonicContact OD2-NH1 2.67Å; D187-R196 PolarHBondContact OD2-NH1 3.48Å; D187-R196 IonicContact OD2-NH2 2.64Å; D187-R196 PolarHBondContact OD2-NH2 3.31Å; P189-R196 HydrophobicContact CG-CB 4.08Å; R196-V198 HydrophobicContact CG-CG2 4.25Å; R196-F215 HydrophobicContact CB-CB 4.48Å; R196-F215 PolarHBondContact N-O 3.4Å; R196-F215 PolarHBondContact O-N 2.78Å; R196-Y336 HydrophobicContact CG-CD1 3.75Å; R196-Y336 HydrophobicContact CG-CD2 4.04Å; R196-Y336 HydrophobicContact CG-CE1 4.41Å; R196-Y336 HydrophobicContact CG-CG 3.55Å
197I98.4Very high96.1Very high16 Ų1643.1 Ų43.18%0.08223%0.227CC..EExtended strand (participates in β ladder)trans-88.9120.2178.6-52.7-52.8000110.3P195 V212 C213 A214 L223 L330 Y336P195-I197 HydrophobicContact CB-CD1 4.42Å; P195-I197 HydrophobicContact CG-CD1 4.14Å; P195-I197 PolarHBondContact O-N 2.91Å; I197-V212 HydrophobicContact CG2-CG1 3.67Å; I197-C213 WeakPolarHBondContact CA-O 3.39Å; I197-A214 HydrophobicContact CD1-CB 3.87Å; I197-L223 HydrophobicContact CD1-CD1 3.98Å; I197-L330 HydrophobicContact CG1-CD1 4.37Å; I197-L330 HydrophobicContact CG2-CD1 3.95Å; I197-Y336 VanDerWaalsContact O-CB 3.25Å; I197-Y336 WeakPolarHBondContact O-CB 3.14Å; I197-Y336 PolarHBondContact O-N 3.03Å
198V98.4Very high96.2Very high0 Ų039 Ų390%021%0.205CC..EExtended strand (participates in β ladder)trans-122.8136.9174.7-177.60000109Y181 R196 F200 C213 F215 Y336 A337 E339Y181-V198 HydrophobicContact CE1-CG2 3.98Å; R196-V198 HydrophobicContact CG-CG2 4.25Å; V198-F200 HydrophobicContact CB-CE2 4.27Å; V198-F200 HydrophobicContact CB-CZ 4.42Å; V198-F200 HydrophobicContact CG1-CE1 4.26Å; V198-F200 HydrophobicContact CG1-CE2 3.98Å; V198-F200 HydrophobicContact CG1-CZ 3.82Å; V198-C213 PolarHBondContact N-O 2.92Å; V198-C213 PolarHBondContact O-N 3.29Å; V198-F215 HydrophobicContact CB-CD2 4.31Å; V198-F215 HydrophobicContact CB-CE2 4.01Å; V198-F215 HydrophobicContact CG2-CD2 4.12Å; V198-F215 HydrophobicContact CG2-CE2 4.21Å; V198-Y336 HydrophobicContact CG2-CD1 4.43Å; V198-A337 WeakPolarHBondContact CA-O 3.32Å; V198-A337 HydrophobicContact CG1-CB 4.36Å; V198-E339 HydrophobicContact CG1-CG 3.85Å
199V98.6Very high96.3Very high0 Ų038.6 Ų38.60%020%0.203CC..EExtended strand (participates in β ladder)trans-98.4130.2171.1-171.70000108.6V201 V210 S211 V212 I335 A337 V338 E339 F358V199-V201 HydrophobicContact CG1-CG2 4.12Å; V199-V210 HydrophobicContact CG1-CG1 3.75Å; V199-S211 WeakPolarHBondContact CA-O 3.41Å; V199-V212 HydrophobicContact CG1-CG2 4.43Å; V199-V212 HydrophobicContact CG2-CG2 4.15Å; V199-I335 HydrophobicContact CG2-CD1 3.76Å; V199-I335 HydrophobicContact CG2-CG1 4.04Å; V199-I335 HydrophobicContact CG2-CG2 3.97Å; V199-A337 PolarHBondContact N-O 2.84Å; V199-V338 HydrophobicContact CB-CG1 4.42Å; V199-V338 HydrophobicContact CB-CG2 4.41Å; V199-V338 CarbonylContact O-C 3.56Å; V199-V338 WeakPolarHBondContact O-CA 3.46Å; V199-E339 PolarHBondContact O-N 3.03Å; V199-F358 HydrophobicContact CB-CZ 4.4Å; V199-F358 HydrophobicContact CG1-CZ 4Å; V199-F358 HydrophobicContact CG2-CE1 4.29Å; V199-F358 HydrophobicContact CG2-CZ 4.27Å
200F98.4Very high96.3Very high1 Ų137.6 Ų37.60%0.00420%0.196CC..EExtended strand (participates in β ladder)trans-103.8133167.8-61.6-85.4000109.2V177 S178 Y181 V198 V210 S211 C213 F215 E339 L366V177-F200 HydrophobicContact CG1-CD1 3.63Å; V177-F200 HydrophobicContact CG1-CE1 4.12Å; V177-F200 HydrophobicContact CG1-CG 4.27Å; S178-F200 WeakPolarHBondContact OG-CD2 3.34Å; S178-F200 VanDerWaalsContact OG-CE2 3.26Å; S178-F200 WeakPolarHBondContact OG-CE2 3.44Å; Y181-F200 AromaticContact CD1-CZ 3.93Å; Y181-F200 HydrophobicContact CD1-CZ 3.93Å; Y181-F200 HydrophobicContact CD2-CE1 4.09Å; Y181-F200 HydrophobicContact CD2-CZ 4.17Å; Y181-F200 AromaticContact CG-CE1 3.99Å; Y181-F200 HydrophobicContact CG-CE1 3.99Å; Y181-F200 AromaticContact CG-CZ 3.67Å; Y181-F200 HydrophobicContact CG-CZ 3.67Å; V198-F200 HydrophobicContact CB-CE2 4.27Å; V198-F200 HydrophobicContact CB-CZ 4.42Å; V198-F200 HydrophobicContact CG1-CE1 4.26Å; V198-F200 HydrophobicContact CG1-CE2 3.98Å; V198-F200 HydrophobicContact CG1-CZ 3.82Å; F200-V210 WeakPolarHBondContact O-CA 3.41Å; F200-S211 PolarHBondContact N-O 3.41Å; F200-S211 PolarHBondContact O-N 2.84Å; F200-C213 HydrophobicContact CD2-CB 4.28Å; F200-C213 HydrophobicContact CE2-CB 4.02Å; F200-F215 AromaticContact CE2-CE2 3.77Å; F200-F215 HydrophobicContact CE2-CE2 3.77Å; F200-F215 AromaticContact CE2-CZ 3.8Å; F200-F215 HydrophobicContact CE2-CZ 3.8Å; F200-F215 HydrophobicContact CZ-CE2 4.07Å; F200-F215 AromaticContact CZ-CZ 3.95Å; F200-F215 HydrophobicContact CZ-CZ 3.95Å; F200-E339 WeakPolarHBondContact CA-O 3.24Å; F200-E339 HydrophobicContact CD1-CB 3.69Å; F200-E339 HydrophobicContact CD1-CG 4.25Å; F200-E339 HydrophobicContact CE1-CB 3.78Å; F200-E339 HydrophobicContact CE1-CG 3.83Å; F200-L366 HydrophobicContact CE1-CD1 4.13Å
201V98.3Very high96.4Very high0 Ų035.7 Ų35.70%018%0.181CC..EExtended strand (participates in β ladder)trans-122.4116.4178.2-1750000108.5V199 Y208 V210 L321 V338 E339 I340 V341 I354V199-V201 HydrophobicContact CG1-CG2 4.12Å; V201-Y208 HydrophobicContact CG1-CE2 3.58Å; V201-V210 HydrophobicContact CG1-CG2 4.43Å; V201-V210 HydrophobicContact CG2-CG1 4.39Å; V201-L321 HydrophobicContact CG2-CD2 4.2Å; V201-V338 HydrophobicContact CG2-CG1 3.96Å; V201-E339 PolarHBondContact N-O 3.34Å; V201-I340 HydrophobicContact CB-CG2 4.32Å; V201-I340 WeakPolarHBondContact O-CA 3.35Å; V201-V341 PolarHBondContact O-N 3.06Å; V201-I354 HydrophobicContact CG1-CD1 3.8Å; V201-I354 HydrophobicContact CG1-CG1 4.46Å; V201-I354 HydrophobicContact CG2-CG2 4.19Å
202D97.9Very high96.7Very high12 Ų1232.7 Ų32.76%0.06416%0.161CC..EExtended strand (participates in β ladder)trans-115.4119.4-178-173.1-4.4000109.6T174 Y208 Q209 V341 G342T174-D202 HydrophobicContact CG2-CB 4.26Å; D202-Y208 CarbonylContact O-C 3.55Å; D202-Y208 WeakPolarHBondContact O-CA 3.36Å; D202-Y208 WeakPolarHBondContact O-CD2 3.31Å; D202-Q209 HydrophobicContact CB-CB 4.38Å; D202-Q209 PolarHBondContact N-O 2.88Å; D202-Q209 PolarHBondContact O-N 2.92Å; D202-V341 WeakPolarHBondContact CA-O 3.46Å; D202-V341 HydrophobicContact CB-CG2 3.66Å; D202-G342 VanDerWaalsContact OD1-CA 3.31Å; D202-G342 WeakPolarHBondContact OD1-CA 3.41Å
203L97.5Very high97Very high0 Ų024 Ų240%012%0.121CC..EExtended strand (participates in β ladder)trans-122.293.9171.4-172.667.3000108.9Y208 L231 V341 G342 G343 A344 T345 I350L203-Y208 HydrophobicContact CB-CD2 4.04Å; L203-Y208 HydrophobicContact CD1-CD2 3.61Å; L203-Y208 HydrophobicContact CD1-CG 3.8Å; L203-Y208 HydrophobicContact CG-CD2 4.36Å; L203-L231 HydrophobicContact CD1-CD2 4.47Å; L203-L231 HydrophobicContact CD1-CG 4.15Å; L203-V341 PolarHBondContact N-O 3Å; L203-G342 CarbonylContact O-C 3.54Å; L203-G343 PolarHBondContact O-N 2.99Å; L203-A344 HydrophobicContact CB-CB 4.47Å; L203-A344 HydrophobicContact CD2-CB 3.88Å; L203-A344 HydrophobicContact CG-CB 3.84Å; L203-A344 WeakPolarHBondContact O-CB 3.31Å; L203-A344 PolarHBondContact O-N 3.08Å; L203-T345 HydrophobicContact CB-CG2 3.61Å; L203-I350 HydrophobicContact CD2-CD1 3.93Å; L203-I350 HydrophobicContact CD2-CG1 4.02Å; L203-I350 HydrophobicContact CD2-CG2 3.99Å
204G95.3Very high97.1Very high21 Ų2118.9 Ų18.922%0.21610%0.098CC..  trans-82-157.3179.200000113G207 G232 G233G204-G207 PolarHBondContact N-O 3.45Å; G204-G232 WeakPolarHBondContact O-CA 3.35Å; G204-G233 PolarHBondContact O-N 3.16Å
205H95.6Very high97.2Very high41 Ų419.7 Ų9.719%0.196%0.058CC..SBendtrans-75.8-31.5178.8175.9-95.1000113.8F10 Q11 G232 G233 K234F10-H205 HydrophobicContact CB-CB 4.34Å; Q11-H205 HydrophobicContact CB-CB 3.79Å; Q11-H205 PolarHBondContact OE1-CD2 3.32Å; H205-G232 CarbonylContact O-C 3.6Å; H205-G233 PolarHBondContact O-N 3.45Å; H205-G233 VanDerWaalsContact O-N 3.13Å; H205-K234 VanDerWaalsContact O-CB 3.29Å; H205-K234 WeakPolarHBondContact O-CB 3.41Å; H205-K234 PolarHBondContact O-N 2.93Å
206S92.2Very high97.2Very high9 Ų97.8 Ų7.86%0.0635%0.045CC..SBendtrans-150.644.1-174-54.10000112Y147Y147-S206 PolarHBondContact OH-O 3.37Å
207G93.2Very high97.1Very high4 Ų411.9 Ų11.94%0.0416%0.064CC..  trans177.7139-179.800000111.6Y147 G204 L231Y147-G207 WeakPolarHBondContact OH-CA 3.37Å; G204-G207 PolarHBondContact N-O 3.45Å; G207-L231 CarbonylContact C-O 3.58Å; G207-L231 WeakPolarHBondContact CA-O 3.43Å; G207-L231 PolarHBondContact N-O 3.26Å
208Y97.3Very high96.8Very high0 Ų012 Ų120%07%0.069CC..EExtended strand (participates in β ladder)trans-118.5128.7176.8178.4-137.5000108.8V201 D202 L203 V210 F227 D228 L231 V317 P320 L321V201-Y208 HydrophobicContact CG1-CE2 3.58Å; D202-Y208 CarbonylContact O-C 3.55Å; D202-Y208 WeakPolarHBondContact O-CA 3.36Å; D202-Y208 WeakPolarHBondContact O-CD2 3.31Å; L203-Y208 HydrophobicContact CB-CD2 4.04Å; L203-Y208 HydrophobicContact CD1-CD2 3.61Å; L203-Y208 HydrophobicContact CD1-CG 3.8Å; L203-Y208 HydrophobicContact CG-CD2 4.36Å; Y208-V210 HydrophobicContact CE1-CG2 4.39Å; Y208-V210 HydrophobicContact CE2-CG2 4.21Å; Y208-F227 CarbonylContact O-C 3.49Å; Y208-F227 WeakPolarHBondContact O-CA 3.48Å; Y208-F227 WeakPolarHBondContact O-CB 3.47Å; Y208-D228 HydrophobicContact CD1-CB 4.24Å; Y208-D228 PolarHBondContact N-O 2.82Å; Y208-D228 PolarHBondContact O-N 2.81Å; Y208-L231 WeakPolarHBondContact CB-O 3.39Å; Y208-L231 HydrophobicContact CD1-CD2 3.75Å; Y208-L231 HydrophobicContact CE1-CD2 4.41Å; Y208-L231 HydrophobicContact CG-CD2 4.08Å; Y208-L231 PolarHBondContact N-O 2.86Å; Y208-V317 VanDerWaalsContact CE1-O 3.22Å; Y208-V317 WeakPolarHBondContact CE1-O 3.45Å; Y208-V317 PolarHBondContact OH-O 2.96Å; Y208-P320 HydrophobicContact CD1-CB 4.22Å; Y208-P320 HydrophobicContact CD1-CG 3.71Å; Y208-P320 HydrophobicContact CE1-CB 3.86Å; Y208-P320 HydrophobicContact CE1-CG 3.67Å; Y208-L321 WeakPolarHBondContact OH-CG 3.48Å
209Q97.1Very high96.7Very high4 Ų416.4 Ų16.42%0.0199%0.088CC..EExtended strand (participates in β ladder)trans-139.8141.3-173.3-62.5175.583.600111.1S146 Y147 E173 T174 D202 F227S146-Q209 PolarHBondContact OG-OE1 3.33Å; Y147-Q209 HydrophobicContact CD1-CG 3.97Å; Y147-Q209 HydrophobicContact CE1-CG 3.81Å; E173-Q209 PolarHBondContact OE2-NE2 2.92Å; T174-Q209 HydrophobicContact CG2-CB 3.71Å; D202-Q209 HydrophobicContact CB-CB 4.38Å; D202-Q209 PolarHBondContact N-O 2.88Å; D202-Q209 PolarHBondContact O-N 2.92Å; Q209-F227 HydrophobicContact CG-CB 4.2Å
210V98.1Very high96.6Very high1 Ų116.4 Ų16.41%0.0069%0.088CC..EExtended strand (participates in β ladder)trans-134128.6179.9-173.30000108.3V199 F200 V201 Y208 A225 A226 P320 L321 V324V199-V210 HydrophobicContact CG1-CG1 3.75Å; F200-V210 WeakPolarHBondContact O-CA 3.41Å; V201-V210 HydrophobicContact CG1-CG2 4.43Å; V201-V210 HydrophobicContact CG2-CG1 4.39Å; Y208-V210 HydrophobicContact CE1-CG2 4.39Å; Y208-V210 HydrophobicContact CE2-CG2 4.21Å; V210-A225 VanDerWaalsContact O-CA 3.3Å; V210-A225 WeakPolarHBondContact O-CA 3.36Å; V210-A226 PolarHBondContact N-O 2.96Å; V210-A226 PolarHBondContact O-N 3.45Å; V210-P320 HydrophobicContact CG2-CB 3.85Å; V210-L321 HydrophobicContact CG1-CD2 4.03Å; V210-L321 HydrophobicContact CG2-CD2 3.86Å; V210-V324 HydrophobicContact CB-CG1 4.08Å; V210-V324 HydrophobicContact CG1-CB 4.45Å; V210-V324 HydrophobicContact CG1-CG1 3.94Å; V210-V324 HydrophobicContact CG1-CG2 3.69Å
211S97.9Very high96.6Very high0 Ų021 Ų210%011%0.108CC..EExtended strand (participates in β ladder)trans-129.8135.2174.263.10000111.6T174 V199 F200 A224T174-S211 WeakPolarHBondContact CB-OG 3.48Å; V199-S211 WeakPolarHBondContact CA-O 3.41Å; F200-S211 PolarHBondContact N-O 3.41Å; F200-S211 PolarHBondContact O-N 2.84Å; S211-A224 WeakPolarHBondContact CA-O 3.4Å
212V98.4Very high96.6Very high0 Ų021.1 Ų21.10%011%0.109CC..EExtended strand (participates in β ladder)trans-101.7123.1174.2-176.70000108.7I197 V199 L223 A224 V324 T328 L330I197-V212 HydrophobicContact CG2-CG1 3.67Å; V199-V212 HydrophobicContact CG1-CG2 4.43Å; V199-V212 HydrophobicContact CG2-CG2 4.15Å; V212-L223 HydrophobicContact CG1-CD1 4.35Å; V212-L223 WeakPolarHBondContact O-CB 3.42Å; V212-L223 PolarHBondContact O-N 2.75Å; V212-A224 PolarHBondContact N-O 2.7Å; V212-V324 HydrophobicContact CG2-CB 3.67Å; V212-V324 HydrophobicContact CG2-CG1 4.41Å; V212-V324 HydrophobicContact CG2-CG2 3.68Å; V212-T328 HydrophobicContact CB-CG2 3.97Å; V212-T328 HydrophobicContact CG1-CG2 4.09Å; V212-T328 HydrophobicContact CG2-CG2 4.27Å; V212-L330 HydrophobicContact CG1-CD1 4.05Å
213C98.1Very high96.6Very high0 Ų022.9 Ų22.90%012%0.118CC..EExtended strand (participates in β ladder)trans-125.3133.2-166.3-59.50000111.5S178 I197 V198 F200 F215 L220 I222S178-C213 PolarHBondContact OG-SG 3.25Å; I197-C213 WeakPolarHBondContact CA-O 3.39Å; V198-C213 PolarHBondContact N-O 2.92Å; V198-C213 PolarHBondContact O-N 3.29Å; F200-C213 HydrophobicContact CD2-CB 4.28Å; F200-C213 HydrophobicContact CE2-CB 4.02Å; C213-F215 HydrophobicContact CB-CD2 4.37Å; C213-F215 HydrophobicContact CB-CE2 3.71Å; C213-F215 HydrophobicContact CB-CZ 4.24Å; C213-L220 HydrophobicContact CB-CD1 3.9Å; C213-I222 WeakPolarHBondContact SG-CD1 3.22Å
214A98.1Very high96.5Very high7 Ų722.9 Ų22.96%0.05812%0.118CC..EExtended strand (participates in β ladder)trans-100.8124.9174.400000110.3P195 I197 K221 L223P195-A214 HydrophobicContact CB-CB 3.8Å; P195-A214 HydrophobicContact CG-CB 4.1Å; I197-A214 HydrophobicContact CD1-CB 3.87Å; A214-K221 PolarHBondContact N-O 3.05Å; A214-K221 PolarHBondContact O-N 3.18Å; A214-L223 HydrophobicContact CB-CD1 4.13Å; A214-L223 HydrophobicContact CB-CD2 3.95Å; A214-L223 HydrophobicContact CB-CG 4.04Å
215F98.2Very high96.5Very high0 Ų022.2 Ų22.20%011%0.11CC..EExtended strand (participates in β ladder)trans-115.6131.9178.4-67.7-87.2000112.8S178 Y181 G182 L188 P195 R196 V198 F200 C213 K219 L220 F392S178-F215 VanDerWaalsContact O-CE1 3.31Å; S178-F215 WeakPolarHBondContact O-CE1 3.43Å; S178-F215 WeakPolarHBondContact O-CZ 3.5Å; Y181-F215 HydrophobicContact CD1-CE1 4.2Å; Y181-F215 HydrophobicContact CD1-CE2 4.02Å; Y181-F215 AromaticContact CD1-CZ 3.8Å; Y181-F215 HydrophobicContact CD1-CZ 3.8Å; Y181-F215 HydrophobicContact CE1-CE2 4.36Å; G182-F215 VanDerWaalsContact CA-CE1 3.49Å; L188-F215 HydrophobicContact CD1-CB 4.24Å; L188-F215 HydrophobicContact CD1-CD1 4.37Å; L188-F215 HydrophobicContact CD2-CB 3.93Å; P195-F215 CarbonylContact C-O 3.55Å; P195-F215 WeakPolarHBondContact CA-O 3.37Å; R196-F215 HydrophobicContact CB-CB 4.48Å; R196-F215 PolarHBondContact N-O 3.4Å; R196-F215 PolarHBondContact O-N 2.78Å; V198-F215 HydrophobicContact CB-CD2 4.31Å; V198-F215 HydrophobicContact CB-CE2 4.01Å; V198-F215 HydrophobicContact CG2-CD2 4.12Å; V198-F215 HydrophobicContact CG2-CE2 4.21Å; F200-F215 AromaticContact CE2-CE2 3.77Å; F200-F215 HydrophobicContact CE2-CE2 3.77Å; F200-F215 AromaticContact CE2-CZ 3.8Å; F200-F215 HydrophobicContact CE2-CZ 3.8Å; F200-F215 HydrophobicContact CZ-CE2 4.07Å; F200-F215 AromaticContact CZ-CZ 3.95Å; F200-F215 HydrophobicContact CZ-CZ 3.95Å; C213-F215 HydrophobicContact CB-CD2 4.37Å; C213-F215 HydrophobicContact CB-CE2 3.71Å; C213-F215 HydrophobicContact CB-CZ 4.24Å; F215-K219 WeakPolarHBondContact CA-O 3.38Å; F215-L220 HydrophobicContact CD1-CB 4.36Å; F215-L220 HydrophobicContact CD1-CD1 4.23Å; F215-L220 HydrophobicContact CE1-CB 4.18Å; F215-L220 HydrophobicContact CE1-CD1 3.7Å; F215-L220 HydrophobicContact CE1-CD2 4.46Å; F215-L220 HydrophobicContact CE1-CG 4.33Å; F215-L220 HydrophobicContact CE2-CD1 4.31Å; F215-L220 HydrophobicContact CZ-CD1 3.75Å; F215-F392 HydrophobicContact CD1-CZ 4.32Å; F215-F392 HydrophobicContact CE1-CZ 4.4Å
216N97Very high96.6Very high13 Ų1320.5 Ų20.57%0.0710%0.103CC..EExtended strand (participates in β ladder)trans-124.8169157.1-57.589.1000108.4P189 A190 E193 G218 K219P189-N216 CarbonylContact O-C 3.59Å; P189-N216 VanDerWaalsContact O-CA 3.32Å; P189-N216 WeakPolarHBondContact O-CA 3.23Å; P189-N216 WeakPolarHBondContact O-CB 3.49Å; A190-N216 PolarHBondContact O-ND2 3.26Å; E193-N216 PolarHBondContact O-ND2 2.84Å; N216-G218 PolarHBondContact O-N 3.44Å; N216-G218 VanDerWaalsContact O-N 3.07Å; N216-K219 HydrophobicContact CB-CB 4.3Å; N216-K219 PolarHBondContact N-O 3.21Å; N216-K219 PolarHBondContact O-N 3.23Å
217K94.8Very high96.7Very high121 Ų12121.9 Ų21.953%0.52611%0.108SC..THydrogen-bonded Turntrans-55.6112.3175.4-173.3175.1-179.2177.60110.5P189P189-K217 PolarHBondContact O-N 3.43Å
218G93.3Very high96.8Very high18 Ų1823.1 Ų23.119%0.18611%0.113CC..THydrogen-bonded Turntrans79.614.7-177.500000115.5N216 F392 S393N216-G218 PolarHBondContact O-N 3.44Å; N216-G218 VanDerWaalsContact O-N 3.07Å; G218-F392 WeakPolarHBondContact O-CA 3.38Å; G218-S393 PolarHBondContact O-N 3Å; G218-S393 PolarHBondContact O-OG 3.09Å
219K95.7Very high96.5Very high92 Ų9223.9 Ų23.940%0.412%0.119SC..EExtended strand (participates in β ladder)trans-149.4122.4-172.5-172.8175.3-176.5-179.60113.1F215 N216 S393F215-K219 WeakPolarHBondContact CA-O 3.38Å; N216-K219 HydrophobicContact CB-CB 4.3Å; N216-K219 PolarHBondContact N-O 3.21Å; N216-K219 PolarHBondContact O-N 3.23Å; K219-S393 WeakPolarHBondContact CA-O 3.49Å; K219-S393 WeakPolarHBondContact CA-OG 3.5Å
220L97.3Very high96.2Very high0 Ų026.6 Ų26.60%013%0.134CC..EExtended strand (participates in β ladder)trans-113.7129.4168.216460.6000109.2C213 F215 I222 F392 S393 I394 T395C213-L220 HydrophobicContact CB-CD1 3.9Å; F215-L220 HydrophobicContact CD1-CB 4.36Å; F215-L220 HydrophobicContact CD1-CD1 4.23Å; F215-L220 HydrophobicContact CE1-CB 4.18Å; F215-L220 HydrophobicContact CE1-CD1 3.7Å; F215-L220 HydrophobicContact CE1-CD2 4.46Å; F215-L220 HydrophobicContact CE1-CG 4.33Å; F215-L220 HydrophobicContact CE2-CD1 4.31Å; F215-L220 HydrophobicContact CZ-CD1 3.75Å; L220-I222 HydrophobicContact CD1-CD1 4.03Å; L220-I222 HydrophobicContact CG-CD1 4.44Å; L220-F392 HydrophobicContact CB-CE1 3.51Å; L220-F392 HydrophobicContact CB-CZ 3.9Å; L220-F392 HydrophobicContact CD2-CE1 4.4Å; L220-S393 PolarHBondContact N-O 3.27Å; L220-I394 HydrophobicContact CD2-CG2 4.17Å; L220-I394 WeakPolarHBondContact O-CA 3.36Å; L220-T395 PolarHBondContact O-N 2.84Å
221K97.6Very high96Very high99 Ų9926.6 Ų26.643%0.4313%0.133SC..EExtended strand (participates in β ladder)trans-125.4123165.2177.8-179.3176.4-170.10110A214 L223 T395A214-K221 PolarHBondContact N-O 3.05Å; A214-K221 PolarHBondContact O-N 3.18Å; K221-L223 HydrophobicContact CD-CD2 4.04Å; K221-L223 HydrophobicContact CG-CD2 4.16Å; K221-T395 HydrophobicContact CG-CG2 4.31Å
222I97.9Very high95.9Very high2 Ų226.6 Ų26.61%0.0113%0.133CC..EExtended strand (participates in β ladder)trans-70.3131.7165.1-46-59.8000108T175 C213 L220 T395 V397T175-I222 HydrophobicContact CG2-CD1 4.17Å; T175-I222 HydrophobicContact CG2-CG1 4.28Å; T175-I222 WeakPolarHBondContact OG1-CD1 3.07Å; C213-I222 WeakPolarHBondContact SG-CD1 3.22Å; L220-I222 HydrophobicContact CD1-CD1 4.03Å; L220-I222 HydrophobicContact CG-CD1 4.44Å; I222-T395 PolarHBondContact N-O 3.2Å; I222-V397 HydrophobicContact CB-CG1 4.12Å; I222-V397 HydrophobicContact CB-CG2 4.06Å; I222-V397 HydrophobicContact CG2-CG1 4.36Å; I222-V397 HydrophobicContact CG2-CG2 3.63Å; I222-V397 WeakPolarHBondContact O-CG1 3.4Å
223L97.3Very high95.9Very high49 Ų4926.7 Ų26.726%0.25714%0.135SC..EExtended strand (participates in β ladder)trans-96.8-42.4179.7-60.4-174.1000112I197 V212 A214 K221 T328 L330I197-L223 HydrophobicContact CD1-CD1 3.98Å; V212-L223 HydrophobicContact CG1-CD1 4.35Å; V212-L223 WeakPolarHBondContact O-CB 3.42Å; V212-L223 PolarHBondContact O-N 2.75Å; A214-L223 HydrophobicContact CB-CD1 4.13Å; A214-L223 HydrophobicContact CB-CD2 3.95Å; A214-L223 HydrophobicContact CB-CG 4.04Å; K221-L223 HydrophobicContact CD-CD2 4.04Å; K221-L223 HydrophobicContact CG-CD2 4.16Å; L223-T328 HydrophobicContact CB-CG2 3.88Å; L223-L330 HydrophobicContact CD1-CD1 4.14Å
224A96.9Very high95.7Very high0 Ų028.6 Ų28.60%014%0.143CC..EExtended strand (participates in β ladder)trans-156.8159.3174.100000110.9S211 V212 Q327 T328 N423S211-A224 WeakPolarHBondContact CA-O 3.4Å; V212-A224 PolarHBondContact N-O 2.7Å; A224-Q327 HydrophobicContact CB-CB 3.83Å; A224-T328 HydrophobicContact CB-CG2 3.57Å; A224-N423 WeakPolarHBondContact CA-OD1 3.31Å
225A95.5Very high95.6Very high6 Ų629.7 Ų29.75%0.0515%0.148CC..EExtended strand (participates in β ladder)trans-132148.1168.400000111.6V210 Q327 N423V210-A225 VanDerWaalsContact O-CA 3.3Å; V210-A225 WeakPolarHBondContact O-CA 3.36Å; A225-Q327 PolarHBondContact O-NE2 3.09Å; A225-Q327 PolarHBondContact O-OE1 2.82Å; A225-N423 PolarHBondContact N-OD1 2.81Å
226A95.9Very high95.6Very high5 Ų529.8 Ų29.84%0.04115%0.148CC..EExtended strand (participates in β ladder)trans-144.2162.616800000110V210 P320 V324V210-A226 PolarHBondContact N-O 2.96Å; V210-A226 PolarHBondContact O-N 3.45Å; A226-P320 HydrophobicContact CB-CB 4.06Å; A226-V324 HydrophobicContact CB-CG1 3.57Å
227F95.8Very high95.6Very high39 Ų3929.4 Ų29.417%0.17115%0.146CC..EExtended strand (participates in β ladder)trans-159.4160.3-16945.3-96.6000111.9Y147 Y208 Q209 Y400Y147-F227 HydrophobicContact CD1-CB 3.77Å; Y147-F227 HydrophobicContact CD1-CD1 4.42Å; Y147-F227 HydrophobicContact CD1-CD2 4.16Å; Y147-F227 AromaticContact CD1-CG 3.86Å; Y147-F227 HydrophobicContact CD1-CG 3.86Å; Y147-F227 HydrophobicContact CE1-CB 4.45Å; Y147-F227 HydrophobicContact CG-CB 4.49Å; Y147-F227 HydrophobicContact CG-CD2 4.06Å; Y147-F227 HydrophobicContact CG-CE2 4.46Å; Y147-F227 HydrophobicContact CG-CG 4.11Å; Y208-F227 CarbonylContact O-C 3.49Å; Y208-F227 WeakPolarHBondContact O-CA 3.48Å; Y208-F227 WeakPolarHBondContact O-CB 3.47Å; Q209-F227 HydrophobicContact CG-CB 4.2Å; F227-Y400 AromaticContact CZ-CE1 3.8Å; F227-Y400 HydrophobicContact CZ-CE1 3.8Å; F227-Y400 AromaticContact CZ-CZ 3.86Å; F227-Y400 WeakPolarHBondContact CZ-OH 3.43Å
228D94.8Very high95.6Very high29 Ų2925.2 Ų25.216%0.15513%0.129CC..EExtended strand (participates in β ladder)trans-125.1114.9158.1-176.1-15.4000106.6Y208 D230 L231 K316 P320Y208-D228 HydrophobicContact CD1-CB 4.24Å; Y208-D228 PolarHBondContact N-O 2.82Å; Y208-D228 PolarHBondContact O-N 2.81Å; D228-D230 PolarHBondContact O-N 2.96Å; D228-D230 WeakPolarHBondContact OD1-CA 3.34Å; D228-D230 PolarHBondContact OD1-N 3.05Å; D228-L231 HydrophobicContact CB-CB 3.98Å; D228-K316 IonicContact OD1-NZ 2.99Å; D228-K316 PolarHBondContact OD1-NZ 2.89Å; D228-K316 WeakPolarHBondContact OD2-CD 3.39Å; D228-K316 WeakPolarHBondContact OD2-CE 3.27Å; D228-K316 IonicContact OD2-NZ 3.9Å; D228-K316 PolarHBondContact OD2-NZ 3.28Å; D228-P320 HydrophobicContact CB-CG 4.21Å
229S91.4Very high95.8Very high17 Ų1726.2 Ų26.212%0.11913%0.13CC..THydrogen-bonded Turntrans-74.6-13-179.447.60000113.5N453S229-N453 PolarHBondContact OG-ND2 3.47Å
230D89.6Confident95.9Very high61 Ų6121.8 Ų21.833%0.32611%0.111SC..THydrogen-bonded Turntrans-124.139-172.9-59.4-79.1000109.5R69 D228 K316 N453R69-D230 IonicContact NH2-OD1 3.28Å; D228-D230 PolarHBondContact O-N 2.96Å; D228-D230 WeakPolarHBondContact OD1-CA 3.34Å; D228-D230 PolarHBondContact OD1-N 3.05Å; D230-K316 PolarHBondContact O-NZ 3.47Å; D230-N453 PolarHBondContact OD2-ND2 2.94Å
231L95.2Very high95.9Very high0 Ų021.8 Ų21.80%011%0.111CC..  trans-144.1114.8168.6-17967.1000109.5L203 G207 Y208 D228 F236 L313 K316 V317L203-L231 HydrophobicContact CD1-CD2 4.47Å; L203-L231 HydrophobicContact CD1-CG 4.15Å; G207-L231 CarbonylContact C-O 3.58Å; G207-L231 WeakPolarHBondContact CA-O 3.43Å; G207-L231 PolarHBondContact N-O 3.26Å; Y208-L231 WeakPolarHBondContact CB-O 3.39Å; Y208-L231 HydrophobicContact CD1-CD2 3.75Å; Y208-L231 HydrophobicContact CE1-CD2 4.41Å; Y208-L231 HydrophobicContact CG-CD2 4.08Å; Y208-L231 PolarHBondContact N-O 2.86Å; D228-L231 HydrophobicContact CB-CB 3.98Å; L231-F236 HydrophobicContact CD1-CE2 4.12Å; L231-F236 HydrophobicContact CD1-CZ 4.44Å; L231-L313 HydrophobicContact CD1-CB 3.96Å; L231-L313 HydrophobicContact CD1-CD2 4.15Å; L231-K316 HydrophobicContact CB-CD 4.4Å; L231-K316 HydrophobicContact CD1-CD 4.17Å; L231-K316 HydrophobicContact CD2-CB 3.83Å; L231-V317 HydrophobicContact CD2-CG2 4.23Å
232G95.9Very high95.8Very high0 Ų020.1 Ų20.10%011%0.107CC..SBendtrans-161.8-178.6172.800000111.4G204 H205 K234 D235 F236G204-G232 WeakPolarHBondContact O-CA 3.35Å; H205-G232 CarbonylContact O-C 3.6Å; G232-K234 PolarHBondContact O-N 3.34Å; G232-K234 VanDerWaalsContact O-N 3.1Å; G232-D235 PolarHBondContact N-OD2 2.69Å; G232-D235 PolarHBondContact O-N 3.08Å; G232-F236 VanDerWaalsContact O-CD2 3.32Å; G232-F236 WeakPolarHBondContact O-CD2 3.46Å
233G96.6Very high95.8Very high3 Ų322.9 Ų22.93%0.03112%0.119CC..Hα-helixtrans-53.1-31.1-179.300000114.8G204 H205 D237 K274G204-G233 PolarHBondContact O-N 3.16Å; H205-G233 PolarHBondContact O-N 3.45Å; H205-G233 VanDerWaalsContact O-N 3.13Å; G233-D237 PolarHBondContact O-N 2.78Å; G233-K274 PolarHBondContact O-NZ 3.46Å
234K94.9Very high95.8Very high40 Ų4020.5 Ų20.517%0.17411%0.107CC..Hα-helixtrans-63.5-40.4176.9169.8170.8155.555.40112.5H205 G232 F236 D237 D238H205-K234 VanDerWaalsContact O-CB 3.29Å; H205-K234 WeakPolarHBondContact O-CB 3.41Å; H205-K234 PolarHBondContact O-N 2.93Å; G232-K234 PolarHBondContact O-N 3.34Å; G232-K234 VanDerWaalsContact O-N 3.1Å; K234-F236 PolarHBondContact O-N 2.97Å; K234-D237 CarbonylContact O-C 3.57Å; K234-D237 WeakPolarHBondContact O-CA 3.39Å; K234-D237 WeakPolarHBondContact O-CB 3.46Å; K234-D237 PolarHBondContact O-N 3.19Å; K234-D238 WeakPolarHBondContact CE-OD2 3.19Å; K234-D238 IonicContact NZ-OD1 3.58Å; K234-D238 PolarHBondContact NZ-OD1 3.33Å; K234-D238 IonicContact NZ-OD2 3.94Å; K234-D238 PolarHBondContact NZ-OD2 3.38Å; K234-D238 PolarHBondContact O-N 3.03Å
235D95.8Very high95.8Very high30 Ų3021 Ų2116%0.1611%0.111CC..Hα-helixtrans-67.2-26.5-173.4-49.5-77.4000111.1G232 I239 L313G232-D235 PolarHBondContact N-OD2 2.69Å; G232-D235 PolarHBondContact O-N 3.08Å; D235-I239 PolarHBondContact O-N 3.38Å; D235-L313 VanDerWaalsContact C-CD1 3.48Å; D235-L313 HydrophobicContact CB-CD1 3.71Å; D235-L313 HydrophobicContact CB-CD2 4.21Å; D235-L313 WeakPolarHBondContact O-CD1 3.41Å
236F97.8Very high95.9Very high1 Ų126.1 Ų26.10%0.00413%0.133CC..Hα-helixtrans-72.8-33.3168-63.6-94.8000113.2L231 G232 K234 L240 K274 F306 C310 L313 L314 I347 I350L231-F236 HydrophobicContact CD1-CE2 4.12Å; L231-F236 HydrophobicContact CD1-CZ 4.44Å; G232-F236 VanDerWaalsContact O-CD2 3.32Å; G232-F236 WeakPolarHBondContact O-CD2 3.46Å; K234-F236 PolarHBondContact O-N 2.97Å; F236-L240 PolarHBondContact O-N 3.05Å; F236-K274 HydrophobicContact CB-CD 3.81Å; F236-F306 HydrophobicContact CB-CE2 4.23Å; F236-F306 HydrophobicContact CB-CZ 4.02Å; F236-F306 HydrophobicContact CD1-CE2 4.38Å; F236-F306 AromaticContact CD1-CZ 3.87Å; F236-F306 HydrophobicContact CD1-CZ 3.87Å; F236-F306 HydrophobicContact CG-CZ 4.37Å; F236-C310 HydrophobicContact CD1-CB 3.85Å; F236-C310 HydrophobicContact CE1-CB 3.83Å; F236-L313 HydrophobicContact CD1-CD1 4.24Å; F236-L313 HydrophobicContact CD2-CD1 4.13Å; F236-L313 HydrophobicContact CE1-CB 4.16Å; F236-L313 HydrophobicContact CE1-CD1 4.3Å; F236-L313 HydrophobicContact CE2-CB 4.44Å; F236-L313 HydrophobicContact CE2-CD1 4.18Å; F236-L313 HydrophobicContact CG-CD1 4.14Å; F236-L313 HydrophobicContact CZ-CB 3.9Å; F236-L313 HydrophobicContact CZ-CD1 4.25Å; F236-L314 HydrophobicContact CE1-CD2 3.98Å; F236-L314 HydrophobicContact CE1-CG 4.33Å; F236-L314 HydrophobicContact CZ-CD2 4.24Å; F236-I347 HydrophobicContact CD1-CD1 4.15Å; F236-I347 HydrophobicContact CD2-CD1 4.27Å; F236-I347 HydrophobicContact CE1-CD1 4.4Å; F236-I347 HydrophobicContact CG-CD1 4.1Å; F236-I350 HydrophobicContact CZ-CD1 4Å
237D97.2Very high96Very high6 Ų627.6 Ų27.63%0.03214%0.14CC..Hα-helixtrans-68.8-38.7171.9-60.6-43.1000110.9G233 K234 I239 L240 V241 E271 K274G233-D237 PolarHBondContact O-N 2.78Å; K234-D237 CarbonylContact O-C 3.57Å; K234-D237 WeakPolarHBondContact O-CA 3.39Å; K234-D237 WeakPolarHBondContact O-CB 3.46Å; K234-D237 PolarHBondContact O-N 3.19Å; D237-I239 VanDerWaalsContact C-N 3.32Å; D237-I239 PolarHBondContact O-N 2.82Å; D237-L240 WeakPolarHBondContact O-CB 3.3Å; D237-L240 PolarHBondContact O-N 2.86Å; D237-L240 VanDerWaalsContact O-N 3.12Å; D237-V241 WeakPolarHBondContact O-CG2 3.49Å; D237-V241 PolarHBondContact O-N 3.09Å; D237-E271 WeakPolarHBondContact OD1-CA 3.5Å; D237-K274 WeakPolarHBondContact OD1-CD 3.48Å; D237-K274 VanDerWaalsContact OD1-CE 3.3Å; D237-K274 WeakPolarHBondContact OD1-CE 3.34Å; D237-K274 IonicContact OD1-NZ 2.69Å; D237-K274 PolarHBondContact OD1-NZ 2.93Å; D237-K274 IonicContact OD2-NZ 3.72Å; D237-K274 PolarHBondContact OD2-NZ 3.2Å
238D95.4Very high96Very high32 Ų3225.8 Ų25.817%0.17113%0.131CC..Hα-helixtrans-61.8-39.7178.3-70.611000111K234 V241 N242 Y267K234-D238 WeakPolarHBondContact CE-OD2 3.19Å; K234-D238 IonicContact NZ-OD1 3.58Å; K234-D238 PolarHBondContact NZ-OD1 3.33Å; K234-D238 IonicContact NZ-OD2 3.94Å; K234-D238 PolarHBondContact NZ-OD2 3.38Å; K234-D238 PolarHBondContact O-N 3.03Å; D238-V241 PolarHBondContact O-N 3.26Å; D238-N242 VanDerWaalsContact O-CB 3.24Å; D238-N242 WeakPolarHBondContact O-CB 3.28Å; D238-N242 PolarHBondContact O-N 2.96Å; D238-N242 PolarHBondContact O-ND2 3.06Å; D238-N242 PolarHBondContact O-OD1 3.16Å; D238-Y267 VanDerWaalsContact OD1-CE1 3.28Å; D238-Y267 WeakPolarHBondContact OD1-CE1 3.19Å; D238-Y267 PolarHBondContact OD1-OH 3.3Å
239I97.3Very high96.1Very high39 Ų3926.7 Ų26.720%0.214%0.143CC..Hα-helixtrans-60.8-44.9172.5-71.1176.9000111.5D235 D237 N242 H243 M309 C310 L313D235-I239 PolarHBondContact O-N 3.38Å; D237-I239 VanDerWaalsContact C-N 3.32Å; D237-I239 PolarHBondContact O-N 2.82Å; I239-N242 PolarHBondContact O-N 2.97Å; I239-H243 WeakPolarHBondContact O-CB 3.42Å; I239-H243 PolarHBondContact O-N 2.97Å; I239-M309 HydrophobicContact CG2-CB 3.88Å; I239-C310 HydrophobicContact CD1-CB 4.38Å; I239-L313 HydrophobicContact CD1-CD1 3.53Å; I239-L313 HydrophobicContact CD1-CG 3.91Å; I239-L313 HydrophobicContact CG1-CD1 4.42Å
240L97.9Very high96.4Very high0 Ų032.1 Ų32.10%016%0.164CC..Hα-helixtrans-64.9-45.9177.6-69.9173.9000112.1F236 D237 N242 H243 F244 C270 K274 M277 L301 F306 M309F236-L240 PolarHBondContact O-N 3.05Å; D237-L240 WeakPolarHBondContact O-CB 3.3Å; D237-L240 PolarHBondContact O-N 2.86Å; D237-L240 VanDerWaalsContact O-N 3.12Å; L240-N242 VanDerWaalsContact C-N 3.34Å; L240-N242 PolarHBondContact O-N 3.4Å; L240-H243 WeakPolarHBondContact O-CB 3.27Å; L240-H243 PolarHBondContact O-N 3.18Å; L240-F244 HydrophobicContact CD2-CE2 4.35Å; L240-F244 WeakPolarHBondContact O-CD2 3.41Å; L240-F244 PolarHBondContact O-N 2.93Å; L240-C270 HydrophobicContact CB-CB 3.81Å; L240-C270 HydrophobicContact CD1-CB 4.33Å; L240-K274 HydrophobicContact CD1-CB 3.9Å; L240-M277 HydrophobicContact CD1-CE 4.07Å; L240-M277 HydrophobicContact CD2-CE 4.19Å; L240-L301 HydrophobicContact CD2-CD2 3.26Å; L240-F306 HydrophobicContact CD1-CD2 4.21Å; L240-F306 HydrophobicContact CD1-CE2 3.94Å; L240-F306 HydrophobicContact CD2-CD2 3.66Å; L240-F306 HydrophobicContact CD2-CE2 4.15Å; L240-F306 HydrophobicContact CG-CD2 3.97Å; L240-F306 HydrophobicContact CG-CE2 3.93Å; L240-M309 HydrophobicContact CD2-CE 4.49Å
241V96.8Very high96.8Very high0 Ų034.1 Ų34.10%017%0.17CC..Hα-helixtrans-62.6-41.8177.4170.80000110.7D237 D238 F244 C245 L263 L266 Y267 C270D237-V241 WeakPolarHBondContact O-CG2 3.49Å; D237-V241 PolarHBondContact O-N 3.09Å; D238-V241 PolarHBondContact O-N 3.26Å; V241-F244 PolarHBondContact O-N 2.77Å; V241-C245 VanDerWaalsContact O-CB 3.26Å; V241-C245 WeakPolarHBondContact O-CB 3.37Å; V241-C245 PolarHBondContact O-N 3.31Å; V241-C245 PolarHBondContact O-SG 3Å; V241-L263 HydrophobicContact CG1-CD1 3.74Å; V241-L266 HydrophobicContact CG1-CD2 4.22Å; V241-L266 HydrophobicContact CG2-CG 4.35Å; V241-Y267 HydrophobicContact CB-CE1 4.29Å; V241-Y267 HydrophobicContact CG1-CD2 4.49Å; V241-Y267 HydrophobicContact CG1-CE2 4.11Å; V241-Y267 HydrophobicContact CG2-CD1 3.62Å; V241-Y267 HydrophobicContact CG2-CD2 4.29Å; V241-Y267 HydrophobicContact CG2-CE1 3.76Å; V241-Y267 HydrophobicContact CG2-CE2 4.42Å; V241-Y267 HydrophobicContact CG2-CG 3.89Å; V241-C270 HydrophobicContact CG2-CB 3.89Å
242N96.3Very high96.8Very high64 Ų6437 Ų3734%0.34218%0.181SC..Hα-helixtrans-59.6-47.4174.7-69.4-24.5000111.4D238 I239 L240 C245 E246 R257D238-N242 VanDerWaalsContact O-CB 3.24Å; D238-N242 WeakPolarHBondContact O-CB 3.28Å; D238-N242 PolarHBondContact O-N 2.96Å; D238-N242 PolarHBondContact O-ND2 3.06Å; D238-N242 PolarHBondContact O-OD1 3.16Å; I239-N242 PolarHBondContact O-N 2.97Å; L240-N242 VanDerWaalsContact C-N 3.34Å; L240-N242 PolarHBondContact O-N 3.4Å; N242-C245 PolarHBondContact O-N 2.93Å; N242-E246 PolarHBondContact O-N 3.41Å; N242-R257 PolarHBondContact OD1-NH2 3.4Å
243H97.6Very high96.8Very high59 Ų5944.8 Ų44.827%0.27322%0.215SC..Hα-helixtrans-58.3-51.7177.5178.292.1000112.4I239 L240 E246 E247 M309I239-H243 WeakPolarHBondContact O-CB 3.42Å; I239-H243 PolarHBondContact O-N 2.97Å; L240-H243 WeakPolarHBondContact O-CB 3.27Å; L240-H243 PolarHBondContact O-N 3.18Å; H243-E246 WeakPolarHBondContact O-CB 3.3Å; H243-E246 PolarHBondContact O-N 2.95Å; H243-E247 PolarHBondContact O-N 3.26Å; H243-M309 HydrophobicContact CB-SD 4.15Å; H243-M309 PolarHBondContact ND1-SD 2.89Å
244F97.9Very high96.7Very high0 Ų044.8 Ų44.80%022%0.215CC..Hα-helixtrans-72.9-30.8-178.8-68-62.4000113.2L240 V241 E246 E247 F248 L266 L273 L286 L301L240-F244 HydrophobicContact CD2-CE2 4.35Å; L240-F244 WeakPolarHBondContact O-CD2 3.41Å; L240-F244 PolarHBondContact O-N 2.93Å; V241-F244 PolarHBondContact O-N 2.77Å; F244-E246 VanDerWaalsContact C-N 3.3Å; F244-E246 PolarHBondContact O-N 2.9Å; F244-E247 PolarHBondContact O-N 2.81Å; F244-F248 HydrophobicContact CB-CD2 4.45Å; F244-F248 HydrophobicContact CB-CE2 4.01Å; F244-F248 HydrophobicContact CB-CZ 4.05Å; F244-F248 HydrophobicContact CD1-CE1 4.2Å; F244-F248 HydrophobicContact CD1-CZ 4.08Å; F244-F248 HydrophobicContact CG-CZ 4.35Å; F244-F248 VanDerWaalsContact O-CB 3.32Å; F244-F248 WeakPolarHBondContact O-CB 3.48Å; F244-F248 WeakPolarHBondContact O-CD2 3.5Å; F244-F248 WeakPolarHBondContact O-CG 3.34Å; F244-F248 PolarHBondContact O-N 2.9Å; F244-L266 HydrophobicContact CB-CD1 3.97Å; F244-L266 HydrophobicContact CB-CD2 4.13Å; F244-L273 HydrophobicContact CE2-CD2 3.71Å; F244-L273 HydrophobicContact CZ-CD2 3.8Å; F244-L286 HydrophobicContact CD1-CD2 4.49Å; F244-L286 HydrophobicContact CD2-CD1 4.08Å; F244-L286 HydrophobicContact CE2-CD1 3.84Å; F244-L286 HydrophobicContact CZ-CB 4.46Å; F244-L286 HydrophobicContact CZ-CD1 4.21Å; F244-L301 HydrophobicContact CZ-CB 4.25Å; F244-L301 HydrophobicContact CZ-CD2 4.42Å
245C96.6Very high96.7Very high11 Ų1147.2 Ų47.27%0.07423%0.229CC..Hα-helixtrans-57.6-44.6167.5-76.70000111.4V241 N242 A249V241-C245 VanDerWaalsContact O-CB 3.26Å; V241-C245 WeakPolarHBondContact O-CB 3.37Å; V241-C245 PolarHBondContact O-N 3.31Å; V241-C245 PolarHBondContact O-SG 3Å; N242-C245 PolarHBondContact O-N 2.93Å; C245-A249 VanDerWaalsContact O-CB 3.31Å; C245-A249 WeakPolarHBondContact O-CB 3.46Å; C245-A249 PolarHBondContact O-N 2.85Å
246E97.3Very high96.5Very high112 Ų11245.9 Ų45.952%0.52322%0.222SC..Hα-helixtrans-67.9-42.7176.3-82.5-164.5-133.600113.1N242 H243 F244 K250N242-E246 PolarHBondContact O-N 3.41Å; H243-E246 WeakPolarHBondContact O-CB 3.3Å; H243-E246 PolarHBondContact O-N 2.95Å; F244-E246 VanDerWaalsContact C-N 3.3Å; F244-E246 PolarHBondContact O-N 2.9Å; E246-K250 WeakPolarHBondContact O-CB 3.2Å; E246-K250 VanDerWaalsContact O-CD 3.26Å; E246-K250 WeakPolarHBondContact O-CD 3.45Å; E246-K250 WeakPolarHBondContact O-CG 3.09Å; E246-K250 PolarHBondContact O-N 2.93Å; E246-K250 VanDerWaalsContact O-N 3.09Å; E246-K250 IonicContact OE2-NZ 2.8Å; E246-K250 PolarHBondContact OE2-NZ 2.81Å
247E97.2Very high96.2Very high37 Ų3751.5 Ų51.517%0.17324%0.244CC..Hα-helixtrans-60.1-48.3176-164.4-156.3150.400110.3H243 F244 A249 K250 K251 S299H243-E247 PolarHBondContact O-N 3.26Å; F244-E247 PolarHBondContact O-N 2.81Å; E247-A249 PolarHBondContact O-N 2.98Å; E247-K250 PolarHBondContact O-N 2.64Å; E247-K250 VanDerWaalsContact O-N 3.1Å; E247-K251 HydrophobicContact CG-CD 4.24Å; E247-K251 WeakPolarHBondContact O-CB 3.45Å; E247-K251 PolarHBondContact O-N 2.86Å; E247-K251 WeakPolarHBondContact OE1-CD 3.41Å; E247-K251 WeakPolarHBondContact OE1-CE 3.12Å; E247-K251 IonicContact OE1-NZ 3.64Å; E247-K251 PolarHBondContact OE1-NZ 2.97Å; E247-S299 VanDerWaalsContact CD-OG 3.28Å; E247-S299 PolarHBondContact OE1-OG 3.2Å; E247-S299 WeakPolarHBondContact OE2-CB 3.5Å; E247-S299 PolarHBondContact OE2-OG 3.01Å
248F97.4Very high95.9Very high0 Ų054.1 Ų54.10%026%0.262CS..Hα-helixtrans-72.3-31.3-174.7-58.2-16000112.7F244 K250 Y252 K253 L254 V256 L266 L286 F291 V297F244-F248 HydrophobicContact CB-CD2 4.45Å; F244-F248 HydrophobicContact CB-CE2 4.01Å; F244-F248 HydrophobicContact CB-CZ 4.05Å; F244-F248 HydrophobicContact CD1-CE1 4.2Å; F244-F248 HydrophobicContact CD1-CZ 4.08Å; F244-F248 HydrophobicContact CG-CZ 4.35Å; F244-F248 VanDerWaalsContact O-CB 3.32Å; F244-F248 WeakPolarHBondContact O-CB 3.48Å; F244-F248 WeakPolarHBondContact O-CD2 3.5Å; F244-F248 WeakPolarHBondContact O-CG 3.34Å; F244-F248 PolarHBondContact O-N 2.9Å; F248-K250 VanDerWaalsContact C-N 3.34Å; F248-Y252 HydrophobicContact CB-CD2 4.2Å; F248-Y252 AromaticContact CD1-CD2 3.69Å; F248-Y252 HydrophobicContact CD1-CD2 3.69Å; F248-Y252 AromaticContact CD1-CE2 3.83Å; F248-Y252 HydrophobicContact CD1-CE2 3.83Å; F248-Y252 HydrophobicContact CE1-CD2 4.44Å; F248-Y252 HydrophobicContact CE1-CE2 4.14Å; F248-Y252 HydrophobicContact CG-CD2 4.14Å; F248-Y252 CarbonylContact O-C 3.54Å; F248-Y252 WeakPolarHBondContact O-CA 3.38Å; F248-Y252 PolarHBondContact O-N 2.99Å; F248-K253 PolarHBondContact O-N 3.12Å; F248-L254 PolarHBondContact O-N 2.87Å; F248-V256 HydrophobicContact CB-CG2 4.43Å; F248-V256 HydrophobicContact CD2-CG2 4.32Å; F248-L266 HydrophobicContact CE2-CD1 4Å; F248-L286 HydrophobicContact CE2-CD2 4.4Å; F248-L286 HydrophobicContact CZ-CD2 3.78Å; F248-F291 HydrophobicContact CD2-CD1 4.4Å; F248-F291 AromaticContact CD2-CE1 3.71Å; F248-F291 HydrophobicContact CD2-CE1 3.71Å; F248-F291 HydrophobicContact CD2-CZ 4.32Å; F248-F291 HydrophobicContact CE2-CE1 4.05Å; F248-F291 HydrophobicContact CE2-CZ 4.38Å; F248-V297 HydrophobicContact CD1-CB 4.35Å; F248-V297 HydrophobicContact CD1-CG1 4.43Å; F248-V297 HydrophobicContact CD2-CB 4.34Å; F248-V297 HydrophobicContact CD2-CG1 4.21Å; F248-V297 HydrophobicContact CD2-CG2 4.25Å; F248-V297 HydrophobicContact CE1-CB 4.03Å; F248-V297 HydrophobicContact CE1-CG2 4.43Å; F248-V297 HydrophobicContact CE2-CB 3.99Å; F248-V297 HydrophobicContact CE2-CG1 4.35Å; F248-V297 HydrophobicContact CE2-CG2 3.62Å; F248-V297 HydrophobicContact CG-CG1 4.24Å; F248-V297 HydrophobicContact CZ-CB 3.83Å; F248-V297 HydrophobicContact CZ-CG2 3.72Å
249A96.8Very high95.7Very high48 Ų4857.4 Ų57.440%0.39728%0.275SS..Hα-helixtrans-63.8-38.316800000112.1C245 E247 K253 L254C245-A249 VanDerWaalsContact O-CB 3.31Å; C245-A249 WeakPolarHBondContact O-CB 3.46Å; C245-A249 PolarHBondContact O-N 2.85Å; E247-A249 PolarHBondContact O-N 2.98Å; A249-K253 WeakPolarHBondContact O-CA 3.42Å; A249-K253 WeakPolarHBondContact O-CD 3.44Å; A249-L254 PolarHBondContact N-O 3.26Å
250K97.3Very high95.4Very high131 Ų13157.9 Ų57.957%0.5728%0.281SS*.Hα-helixtrans-75.2-45.8179-68.4162.4-163.9169.10112.3E246 E247 F248 K253E246-K250 WeakPolarHBondContact O-CB 3.2Å; E246-K250 VanDerWaalsContact O-CD 3.26Å; E246-K250 WeakPolarHBondContact O-CD 3.45Å; E246-K250 WeakPolarHBondContact O-CG 3.09Å; E246-K250 PolarHBondContact O-N 2.93Å; E246-K250 VanDerWaalsContact O-N 3.09Å; E246-K250 IonicContact OE2-NZ 2.8Å; E246-K250 PolarHBondContact OE2-NZ 2.81Å; E247-K250 PolarHBondContact O-N 2.64Å; E247-K250 VanDerWaalsContact O-N 3.1Å; F248-K250 VanDerWaalsContact C-N 3.34Å; K250-K253 PolarHBondContact O-NZ 3.41Å
251K96.9Very high95.1Very high103 Ų10364.6 Ų64.645%0.44831%0.306SS..Hα-helixtrans-88.9-49.3-169.6-175.7177.9178.8-174.30113.7E247 S298E247-K251 HydrophobicContact CG-CD 4.24Å; E247-K251 WeakPolarHBondContact O-CB 3.45Å; E247-K251 PolarHBondContact O-N 2.86Å; E247-K251 WeakPolarHBondContact OE1-CD 3.41Å; E247-K251 WeakPolarHBondContact OE1-CE 3.12Å; E247-K251 IonicContact OE1-NZ 3.64Å; E247-K251 PolarHBondContact OE1-NZ 2.97Å; K251-S298 PolarHBondContact NZ-O 3.34Å
252Y95.6Very high94.9Very high60 Ų6064.8 Ų64.824%0.23531%0.308CS..THydrogen-bonded Turntrans-104.9-5.6-175.2-61.1-76.2000113.7F248 L254 I295 V297 S298F248-Y252 HydrophobicContact CB-CD2 4.2Å; F248-Y252 AromaticContact CD1-CD2 3.69Å; F248-Y252 HydrophobicContact CD1-CD2 3.69Å; F248-Y252 AromaticContact CD1-CE2 3.83Å; F248-Y252 HydrophobicContact CD1-CE2 3.83Å; F248-Y252 HydrophobicContact CE1-CD2 4.44Å; F248-Y252 HydrophobicContact CE1-CE2 4.14Å; F248-Y252 HydrophobicContact CG-CD2 4.14Å; F248-Y252 CarbonylContact O-C 3.54Å; F248-Y252 WeakPolarHBondContact O-CA 3.38Å; F248-Y252 PolarHBondContact O-N 2.99Å; Y252-L254 PolarHBondContact O-N 2.99Å; Y252-I295 HydrophobicContact CD1-CG2 3.88Å; Y252-I295 HydrophobicContact CG-CG2 4.45Å; Y252-V297 HydrophobicContact CD1-CG1 4.46Å; Y252-V297 HydrophobicContact CD2-CB 4.19Å; Y252-V297 HydrophobicContact CD2-CG1 3.65Å; Y252-V297 HydrophobicContact CE2-CB 3.86Å; Y252-V297 HydrophobicContact CE2-CG1 3.83Å; Y252-V297 HydrophobicContact CG-CG1 4Å; Y252-S298 PolarHBondContact OH-N 2.9Å; Y252-S298 PolarHBondContact OH-O 2.87Å; Y252-S298 VanDerWaalsContact OH-O 3.12Å
253K96.2Very high94.8Very high164 Ų16462.9 Ų62.971%0.71330%0.298SS*.  trans60.228.7-174.5-47.5-50.7-175.9-167.30113.9F248 A249 K250F248-K253 PolarHBondContact O-N 3.12Å; A249-K253 WeakPolarHBondContact O-CA 3.42Å; A249-K253 WeakPolarHBondContact O-CD 3.44Å; K250-K253 PolarHBondContact O-NZ 3.41Å
254L95.1Very high94.5Very high3 Ų360.5 Ų60.52%0.01629%0.287CS..  trans-94.4120.6-179.3-63.6175.6000111.6F248 A249 Y252 V256 F291 M292 I295 V297F248-L254 PolarHBondContact O-N 2.87Å; A249-L254 PolarHBondContact N-O 3.26Å; Y252-L254 PolarHBondContact O-N 2.99Å; L254-V256 PolarHBondContact O-N 2.67Å; L254-F291 HydrophobicContact CD1-CD1 4.03Å; L254-M292 HydrophobicContact CB-SD 4.28Å; L254-M292 HydrophobicContact CD1-CB 4.31Å; L254-M292 HydrophobicContact CD2-CB 4.1Å; L254-M292 HydrophobicContact CD2-CE 4.36Å; L254-M292 HydrophobicContact CD2-CG 3.95Å; L254-M292 HydrophobicContact CD2-SD 4.12Å; L254-I295 HydrophobicContact CD1-CG2 4.26Å; L254-I295 HydrophobicContact CD2-CD1 4.17Å; L254-V297 HydrophobicContact CD1-CG1 3.74Å
255D94Very high94.4Very high91 Ų9163.7 Ų63.749%0.48730%0.299SS..  trans-86.290.1163.9179.31000110.2R257 S258D255-R257 VanDerWaalsContact C-N 3.29Å; D255-R257 PolarHBondContact O-N 2.87Å; D255-R257 PolarHBondContact OD1-N 3.28Å; D255-S258 PolarHBondContact O-N 2.93Å; D255-S258 PolarHBondContact O-OG 3.36Å; D255-S258 PolarHBondContact OD1-N 3.4Å; D255-S258 VanDerWaalsContact OD1-N 3.11Å; D255-S258 WeakPolarHBondContact OD2-CB 3.42Å
256V92.9Very high94.3Very high2 Ų263.2 Ų63.21%0.01230%0.296CS..SBendtrans-61.9-34.5177.8-172.50000112.3F248 L254 S258 K259 A262 L263 L266 F291F248-V256 HydrophobicContact CB-CG2 4.43Å; F248-V256 HydrophobicContact CD2-CG2 4.32Å; L254-V256 PolarHBondContact O-N 2.67Å; V256-S258 VanDerWaalsContact C-N 3.29Å; V256-S258 PolarHBondContact O-N 2.96Å; V256-K259 PolarHBondContact O-N 3.13Å; V256-K259 VanDerWaalsContact O-N 3.11Å; V256-A262 HydrophobicContact CG1-CB 4.18Å; V256-L263 HydrophobicContact CG1-CB 4.31Å; V256-L263 HydrophobicContact CG1-CD1 4.35Å; V256-L266 HydrophobicContact CG1-CD2 4.03Å; V256-F291 HydrophobicContact CG1-CE1 4.23Å; V256-F291 HydrophobicContact CG1-CZ 3.7Å; V256-F291 HydrophobicContact CG2-CE1 3.65Å; V256-F291 HydrophobicContact CG2-CZ 3.96Å
257R90.7Very high94.2Very high120 Ų12060.3 Ų60.345%0.45328%0.28SS..THydrogen-bonded Turntrans-68.3-31.6-176.3-63.4-171.6-170.7-92.2-1.4111.5N242 D255 K259N242-R257 PolarHBondContact OD1-NH2 3.4Å; D255-R257 VanDerWaalsContact C-N 3.29Å; D255-R257 PolarHBondContact O-N 2.87Å; D255-R257 PolarHBondContact OD1-N 3.28Å; R257-K259 PolarHBondContact O-N 3.49Å
258S90.3Very high94.1Very high60 Ų6061 Ų6142%0.4228%0.283SS..THydrogen-bonded Turntrans-65.3-16173.577.40000114.9D255 V256D255-S258 PolarHBondContact O-N 2.93Å; D255-S258 PolarHBondContact O-OG 3.36Å; D255-S258 PolarHBondContact OD1-N 3.4Å; D255-S258 VanDerWaalsContact OD1-N 3.11Å; D255-S258 WeakPolarHBondContact OD2-CB 3.42Å; V256-S258 VanDerWaalsContact C-N 3.29Å; V256-S258 PolarHBondContact O-N 2.96Å
259K91.4Very high94.1Very high101 Ų10163.1 Ų63.144%0.43929%0.293SS..  trans-123.194-173.9-59.7-55.6176.6-176.40111.4V256 R257 R261 A262 L263 M292V256-K259 PolarHBondContact O-N 3.13Å; V256-K259 VanDerWaalsContact O-N 3.11Å; R257-K259 PolarHBondContact O-N 3.49Å; K259-R261 VanDerWaalsContact C-N 3.27Å; K259-R261 PolarHBondContact O-N 3.24Å; K259-R261 VanDerWaalsContact O-N 3.1Å; K259-A262 HydrophobicContact CB-CB 4.01Å; K259-A262 WeakPolarHBondContact O-CB 3.38Å; K259-A262 PolarHBondContact O-N 3.36Å; K259-L263 PolarHBondContact O-N 2.91Å; K259-M292 HydrophobicContact CB-SD 4.19Å; K259-M292 HydrophobicContact CG-CE 3.62Å; K259-M292 HydrophobicContact CG-CG 4.28Å; K259-M292 HydrophobicContact CG-SD 3.61Å
260P90.5Very high94.1Very high49 Ų4960.8 Ų60.832%0.31827%0.274SS..Hα-helixtrans-56.4-33.8-175.3-27.934.5000115.2V88 L263 V264V88-P260 HydrophobicContact CB-CB 4.45Å; V88-P260 HydrophobicContact CG1-CB 3.58Å; V88-P260 HydrophobicContact CG2-CB 4.12Å; P260-L263 PolarHBondContact O-N 3.34Å; P260-V264 WeakPolarHBondContact O-CB 3.43Å; P260-V264 VanDerWaalsContact O-CG2 3.26Å; P260-V264 WeakPolarHBondContact O-CG2 3.17Å; P260-V264 PolarHBondContact O-N 3.21Å
261R91.8Very high94.1Very high141 Ų14155.8 Ų55.853%0.53225%0.253SS..Hα-helixtrans-64.5-37.6174.9-64.4-176.870.3-166.6-2.9112.7V57 K259 R265V57-R261 WeakPolarHBondContact O-CG 3.49Å; V57-R261 PolarHBondContact O-NE 3.26Å; K259-R261 VanDerWaalsContact C-N 3.27Å; K259-R261 PolarHBondContact O-N 3.24Å; K259-R261 VanDerWaalsContact O-N 3.1Å; R261-R265 WeakPolarHBondContact O-CG 3.45Å; R261-R265 PolarHBondContact O-N 3.24Å
262A93.5Very high94Very high5 Ų556 Ų564%0.04125%0.254CS..Hα-helixtrans-72.6-42.5175.400000111V256 K259 V264 R265 L266 F291 M292V256-A262 HydrophobicContact CG1-CB 4.18Å; K259-A262 HydrophobicContact CB-CB 4.01Å; K259-A262 WeakPolarHBondContact O-CB 3.38Å; K259-A262 PolarHBondContact O-N 3.36Å; A262-V264 PolarHBondContact O-N 2.96Å; A262-R265 PolarHBondContact O-N 2.93Å; A262-L266 PolarHBondContact O-N 3.42Å; A262-F291 HydrophobicContact CB-CD2 4.48Å; A262-F291 HydrophobicContact CB-CE2 4.05Å; A262-F291 HydrophobicContact CB-CZ 4.12Å; A262-F291 VanDerWaalsContact O-CE2 3.29Å; A262-F291 WeakPolarHBondContact O-CE2 3.48Å; A262-M292 HydrophobicContact CB-CB 4.38Å
263L92.8Very high94.1Very high24 Ų2453.3 Ų53.313%0.12624%0.244CC..Hα-helixtrans-59-45176.1-174.561.7000112.2V241 V256 K259 P260 L266 Y267V241-L263 HydrophobicContact CG1-CD1 3.74Å; V256-L263 HydrophobicContact CG1-CB 4.31Å; V256-L263 HydrophobicContact CG1-CD1 4.35Å; K259-L263 PolarHBondContact O-N 2.91Å; P260-L263 PolarHBondContact O-N 3.34Å; L263-L266 PolarHBondContact O-N 3.21Å; L263-Y267 HydrophobicContact CD1-CD2 4.23Å; L263-Y267 HydrophobicContact CD1-CE2 3.94Å; L263-Y267 HydrophobicContact CD2-CE2 4.44Å; L263-Y267 HydrophobicContact CG-CD2 4.07Å; L263-Y267 HydrophobicContact CG-CE2 3.92Å; L263-Y267 VanDerWaalsContact O-CD2 3.3Å; L263-Y267 WeakPolarHBondContact O-CD2 3.31Å; L263-Y267 PolarHBondContact O-N 2.83Å
264V92.9Very high94.2Very high8 Ų846.2 Ų46.25%0.04821%0.213CC..Hα-helixtrans-62.9-41.5176.5170.90000111.9V56 V57 V88 P260 A262 Y267 Q268V56-V264 HydrophobicContact CB-CG1 4.46Å; V56-V264 HydrophobicContact CG1-CG1 3.86Å; V56-V264 HydrophobicContact CG2-CG1 3.96Å; V57-V264 HydrophobicContact CG2-CG1 3.98Å; V88-V264 HydrophobicContact CG2-CG2 3.98Å; P260-V264 WeakPolarHBondContact O-CB 3.43Å; P260-V264 VanDerWaalsContact O-CG2 3.26Å; P260-V264 WeakPolarHBondContact O-CG2 3.17Å; P260-V264 PolarHBondContact O-N 3.21Å; A262-V264 PolarHBondContact O-N 2.96Å; V264-Y267 PolarHBondContact O-N 3.26Å; V264-Q268 WeakPolarHBondContact O-CG 3.24Å; V264-Q268 PolarHBondContact O-N 2.94Å; V264-Q268 VanDerWaalsContact O-N 3.16Å
265R94.6Very high94.3Very high68 Ų6851.8 Ų51.826%0.25724%0.237SC..Hα-helixtrans-62.1-43.5173.9-71.2173.674.8-166.85.2111.4V57 R261 A262 Y267 Q268 E269 E289 C290 F291V57-R265 HydrophobicContact CG1-CG 3.7Å; V57-R265 HydrophobicContact CG2-CG 3.98Å; R261-R265 WeakPolarHBondContact O-CG 3.45Å; R261-R265 PolarHBondContact O-N 3.24Å; A262-R265 PolarHBondContact O-N 2.93Å; R265-Y267 PolarHBondContact O-N 3.32Å; R265-Q268 PolarHBondContact O-N 3.33Å; R265-Q268 VanDerWaalsContact O-N 3.16Å; R265-E269 PolarHBondContact O-N 2.84Å; R265-E269 VanDerWaalsContact O-N 3.08Å; R265-E289 PolarHBondContact NH1-O 2.92Å; R265-E289 PolarHBondContact NH2-O 2.67Å; R265-C290 PolarHBondContact NH1-O 2.72Å; R265-F291 HydrophobicContact CB-CE2 4.44Å
266L95.9Very high94.5Very high0 Ų051.7 Ų51.70%024%0.236CC..Hα-helixtrans-62-42.5177.6-173.156.8000111.7V241 F244 F248 V256 A262 L263 Q268 E269 C270 L286 I288 F291V241-L266 HydrophobicContact CG1-CD2 4.22Å; V241-L266 HydrophobicContact CG2-CG 4.35Å; F244-L266 HydrophobicContact CB-CD1 3.97Å; F244-L266 HydrophobicContact CB-CD2 4.13Å; F248-L266 HydrophobicContact CE2-CD1 4Å; V256-L266 HydrophobicContact CG1-CD2 4.03Å; A262-L266 PolarHBondContact O-N 3.42Å; L263-L266 PolarHBondContact O-N 3.21Å; L266-Q268 VanDerWaalsContact C-N 3.32Å; L266-Q268 PolarHBondContact O-N 2.84Å; L266-E269 PolarHBondContact O-N 2.89Å; L266-C270 WeakPolarHBondContact O-CB 3.37Å; L266-C270 PolarHBondContact O-N 3.42Å; L266-C270 PolarHBondContact O-SG 2.93Å; L266-L286 HydrophobicContact CD1-CD2 4.4Å; L266-I288 HydrophobicContact CD1-CD1 4Å; L266-F291 HydrophobicContact CB-CE2 4.1Å; L266-F291 HydrophobicContact CB-CZ 4.02Å; L266-F291 HydrophobicContact CD2-CZ 4.36Å
267Y94.7Very high94.7Very high51 Ų5151.7 Ų51.720%0.224%0.236CC..Hα-helixtrans-55.4-44.2172.4-91.7-71.2000112.7D238 V241 L263 V264 R265 C270 E271D238-Y267 VanDerWaalsContact OD1-CE1 3.28Å; D238-Y267 WeakPolarHBondContact OD1-CE1 3.19Å; D238-Y267 PolarHBondContact OD1-OH 3.3Å; V241-Y267 HydrophobicContact CB-CE1 4.29Å; V241-Y267 HydrophobicContact CG1-CD2 4.49Å; V241-Y267 HydrophobicContact CG1-CE2 4.11Å; V241-Y267 HydrophobicContact CG2-CD1 3.62Å; V241-Y267 HydrophobicContact CG2-CD2 4.29Å; V241-Y267 HydrophobicContact CG2-CE1 3.76Å; V241-Y267 HydrophobicContact CG2-CE2 4.42Å; V241-Y267 HydrophobicContact CG2-CG 3.89Å; L263-Y267 HydrophobicContact CD1-CD2 4.23Å; L263-Y267 HydrophobicContact CD1-CE2 3.94Å; L263-Y267 HydrophobicContact CD2-CE2 4.44Å; L263-Y267 HydrophobicContact CG-CD2 4.07Å; L263-Y267 HydrophobicContact CG-CE2 3.92Å; L263-Y267 VanDerWaalsContact O-CD2 3.3Å; L263-Y267 WeakPolarHBondContact O-CD2 3.31Å; L263-Y267 PolarHBondContact O-N 2.83Å; V264-Y267 PolarHBondContact O-N 3.26Å; R265-Y267 PolarHBondContact O-N 3.32Å; Y267-C270 PolarHBondContact O-N 3.5Å; Y267-E271 WeakPolarHBondContact O-CB 3.42Å; Y267-E271 PolarHBondContact O-N 2.89Å
268Q94.7Very high95Very high51 Ų5147.3 Ų47.324%0.23822%0.224CC..Hα-helixtrans-64.2-41.6178.8-69.9176-28.100112.4V56 V264 R265 L266 K272V56-Q268 VanDerWaalsContact CG1-NE2 3.27Å; V264-Q268 WeakPolarHBondContact O-CG 3.24Å; V264-Q268 PolarHBondContact O-N 2.94Å; V264-Q268 VanDerWaalsContact O-N 3.16Å; R265-Q268 PolarHBondContact O-N 3.33Å; R265-Q268 VanDerWaalsContact O-N 3.16Å; L266-Q268 VanDerWaalsContact C-N 3.32Å; L266-Q268 PolarHBondContact O-N 2.84Å; Q268-K272 WeakPolarHBondContact O-CD 3.29Å; Q268-K272 VanDerWaalsContact O-CG 3.32Å; Q268-K272 WeakPolarHBondContact O-CG 3.33Å; Q268-K272 PolarHBondContact O-N 3.18Å; Q268-K272 VanDerWaalsContact O-N 3.14Å
269E96.8Very high95.2Very high45 Ų4548.2 Ų48.221%0.2123%0.234CC..Hα-helixtrans-74.6-34.2177.9-56.2-40.3121.100112.9R265 L266 K272 L273 L286 I288R265-E269 PolarHBondContact O-N 2.84Å; R265-E269 VanDerWaalsContact O-N 3.08Å; L266-E269 PolarHBondContact O-N 2.89Å; E269-K272 PolarHBondContact O-N 2.94Å; E269-K272 IonicContact OE1-NZ 3.18Å; E269-K272 PolarHBondContact OE1-NZ 3.44Å; E269-K272 WeakPolarHBondContact OE2-CD 3.48Å; E269-K272 IonicContact OE2-NZ 2.77Å; E269-K272 PolarHBondContact OE2-NZ 2.97Å; E269-L273 VanDerWaalsContact O-CB 3.28Å; E269-L273 WeakPolarHBondContact O-CB 3.5Å; E269-L273 PolarHBondContact O-N 3.19Å; E269-L286 HydrophobicContact CB-CD1 3.96Å; E269-L286 HydrophobicContact CB-CG 4.3Å; E269-I288 HydrophobicContact CB-CD1 4.01Å; E269-I288 HydrophobicContact CB-CG1 4.46Å; E269-I288 HydrophobicContact CG-CD1 3.71Å; E269-I288 HydrophobicContact CG-CG1 3.95Å
270C97.5Very high95.4Very high0 Ų046.9 Ų46.90%023%0.232CC..Hα-helixtrans-63.8-42171.1-690000112L240 V241 L266 Y267 K272 L273 K274L240-C270 HydrophobicContact CB-CB 3.81Å; L240-C270 HydrophobicContact CD1-CB 4.33Å; V241-C270 HydrophobicContact CG2-CB 3.89Å; L266-C270 WeakPolarHBondContact O-CB 3.37Å; L266-C270 PolarHBondContact O-N 3.42Å; L266-C270 PolarHBondContact O-SG 2.93Å; Y267-C270 PolarHBondContact O-N 3.5Å; C270-K272 PolarHBondContact O-N 3.47Å; C270-L273 PolarHBondContact O-N 3.06Å; C270-K274 WeakPolarHBondContact O-CB 3.25Å; C270-K274 PolarHBondContact O-N 2.71Å
271E96.4Very high95.6Very high26 Ų2648.5 Ų48.512%0.12125%0.245CC..Hα-helixtrans-61.9-43.6176.4-165.5-154158.700111.6Q11 D237 Y267 K275Q11-E271 PolarHBondContact NE2-OE1 2.98Å; Q11-E271 PolarHBondContact NE2-OE2 2.84Å; D237-E271 WeakPolarHBondContact OD1-CA 3.5Å; Y267-E271 WeakPolarHBondContact O-CB 3.42Å; Y267-E271 PolarHBondContact O-N 2.89Å; E271-K275 WeakPolarHBondContact O-CG 3.42Å; E271-K275 PolarHBondContact O-N 2.91Å; E271-K275 VanDerWaalsContact O-N 3.16Å; E271-K275 WeakPolarHBondContact OE1-CE 3.42Å; E271-K275 IonicContact OE1-NZ 3.78Å; E271-K275 PolarHBondContact OE1-NZ 2.93Å
272K96.8Very high95.7Very high107 Ų10745 Ų4547%0.46524%0.242SC..Hα-helixtrans-61.6-48.2173.2-72.1162.9175.8175.70111.2Q268 E269 C270 K274 K275 L276Q268-K272 WeakPolarHBondContact O-CD 3.29Å; Q268-K272 VanDerWaalsContact O-CG 3.32Å; Q268-K272 WeakPolarHBondContact O-CG 3.33Å; Q268-K272 PolarHBondContact O-N 3.18Å; Q268-K272 VanDerWaalsContact O-N 3.14Å; E269-K272 PolarHBondContact O-N 2.94Å; E269-K272 IonicContact OE1-NZ 3.18Å; E269-K272 PolarHBondContact OE1-NZ 3.44Å; E269-K272 WeakPolarHBondContact OE2-CD 3.48Å; E269-K272 IonicContact OE2-NZ 2.77Å; E269-K272 PolarHBondContact OE2-NZ 2.97Å; C270-K272 PolarHBondContact O-N 3.47Å; K272-K274 PolarHBondContact O-N 3.29Å; K272-K275 WeakPolarHBondContact O-CB 3.48Å; K272-K275 PolarHBondContact O-N 2.98Å; K272-K275 VanDerWaalsContact O-N 3.14Å; K272-L276 WeakPolarHBondContact O-CG 3.37Å; K272-L276 PolarHBondContact O-N 3.06Å
273L97.8Very high95.8Very high4 Ų448.2 Ų48.22%0.02126%0.259CS..Hα-helixtrans-60.1-44.5-179.5-174.467.5000111.5F244 E269 C270 K275 L276 M277 L284 L286 L301F244-L273 HydrophobicContact CE2-CD2 3.71Å; F244-L273 HydrophobicContact CZ-CD2 3.8Å; E269-L273 VanDerWaalsContact O-CB 3.28Å; E269-L273 WeakPolarHBondContact O-CB 3.5Å; E269-L273 PolarHBondContact O-N 3.19Å; C270-L273 PolarHBondContact O-N 3.06Å; L273-K275 VanDerWaalsContact C-N 3.33Å; L273-K275 PolarHBondContact O-N 3.35Å; L273-L276 PolarHBondContact O-N 3.28Å; L273-M277 HydrophobicContact CG-CE 4.15Å; L273-M277 HydrophobicContact CG-SD 4.48Å; L273-M277 WeakPolarHBondContact O-CB 3.25Å; L273-M277 WeakPolarHBondContact O-CG 3.38Å; L273-M277 PolarHBondContact O-N 3.48Å; L273-L284 HydrophobicContact CD1-CB 3.7Å; L273-L284 HydrophobicContact CD1-CD1 4.45Å; L273-L286 HydrophobicContact CD2-CB 4.34Å; L273-L286 HydrophobicContact CD2-CD1 3.98Å; L273-L301 HydrophobicContact CD2-CB 4.08Å; L273-L301 HydrophobicContact CD2-CD2 4.3Å
274K97.7Very high96Very high15 Ų1548.1 Ų48.17%0.06526%0.258CS..Hα-helixtrans-56.8-43.4173.4-175.2-174.673.2-157.30112.4G233 F236 D237 L240 C270 K272 S278 F306 I347G233-K274 PolarHBondContact O-NZ 3.46Å; F236-K274 HydrophobicContact CB-CD 3.81Å; D237-K274 WeakPolarHBondContact OD1-CD 3.48Å; D237-K274 VanDerWaalsContact OD1-CE 3.3Å; D237-K274 WeakPolarHBondContact OD1-CE 3.34Å; D237-K274 IonicContact OD1-NZ 2.69Å; D237-K274 PolarHBondContact OD1-NZ 2.93Å; D237-K274 IonicContact OD2-NZ 3.72Å; D237-K274 PolarHBondContact OD2-NZ 3.2Å; L240-K274 HydrophobicContact CD1-CB 3.9Å; C270-K274 WeakPolarHBondContact O-CB 3.25Å; C270-K274 PolarHBondContact O-N 2.71Å; K272-K274 PolarHBondContact O-N 3.29Å; K274-S278 PolarHBondContact O-N 2.85Å; K274-S278 VanDerWaalsContact O-N 3.1Å; K274-S278 PolarHBondContact O-OG 2.86Å; K274-F306 HydrophobicContact CD-CZ 4.37Å; K274-F306 HydrophobicContact CG-CE1 4.4Å; K274-F306 HydrophobicContact CG-CZ 3.86Å; K274-I347 HydrophobicContact CD-CD1 4.41Å
275K97.1Very high96.2Very high120 Ų12051.8 Ų51.852%0.52228%0.282SS..Hα-helixtrans-66.5-43.7176.7-74170171177.50111.6E271 K272 L273 S278E271-K275 WeakPolarHBondContact O-CG 3.42Å; E271-K275 PolarHBondContact O-N 2.91Å; E271-K275 VanDerWaalsContact O-N 3.16Å; E271-K275 WeakPolarHBondContact OE1-CE 3.42Å; E271-K275 IonicContact OE1-NZ 3.78Å; E271-K275 PolarHBondContact OE1-NZ 2.93Å; K272-K275 WeakPolarHBondContact O-CB 3.48Å; K272-K275 PolarHBondContact O-N 2.98Å; K272-K275 VanDerWaalsContact O-N 3.14Å; L273-K275 VanDerWaalsContact C-N 3.33Å; L273-K275 PolarHBondContact O-N 3.35Å; K275-S278 WeakPolarHBondContact O-CB 3.5Å; K275-S278 PolarHBondContact O-N 3.33Å; K275-S278 VanDerWaalsContact O-N 3.16Å
276L97.3Very high96.3Very high88 Ų8848.8 Ų48.846%0.46127%0.271SS..Hα-helixtrans-65.1-39176.3-68.4170.7000112.5K272 L273 S278 A279 N280 L284K272-L276 WeakPolarHBondContact O-CG 3.37Å; K272-L276 PolarHBondContact O-N 3.06Å; L273-L276 PolarHBondContact O-N 3.28Å; L276-S278 VanDerWaalsContact C-N 3.25Å; L276-S278 PolarHBondContact O-N 2.99Å; L276-A279 PolarHBondContact O-N 3.01Å; L276-N280 PolarHBondContact O-N 3.39Å; L276-N280 PolarHBondContact O-ND2 3.1Å; L276-L284 HydrophobicContact CB-CD1 3.66Å
277M97.2Very high96.3Very high2 Ų253.3 Ų53.31%0.0130%0.295CS..Hα-helixtrans-66.2-24.4173-74.7-172.6-58.600112.9L240 L273 A279 N280 L284 L301 R303 F306L240-M277 HydrophobicContact CD1-CE 4.07Å; L240-M277 HydrophobicContact CD2-CE 4.19Å; L273-M277 HydrophobicContact CG-CE 4.15Å; L273-M277 HydrophobicContact CG-SD 4.48Å; L273-M277 WeakPolarHBondContact O-CB 3.25Å; L273-M277 WeakPolarHBondContact O-CG 3.38Å; L273-M277 PolarHBondContact O-N 3.48Å; M277-A279 VanDerWaalsContact C-N 3.26Å; M277-A279 PolarHBondContact O-N 3.26Å; M277-N280 CarbonylContact C-O 3.57Å; M277-N280 WeakPolarHBondContact CA-O 3.48Å; M277-L284 HydrophobicContact CB-CD1 4.37Å; M277-L284 HydrophobicContact CG-CD1 3.68Å; M277-L301 HydrophobicContact CE-CD2 4.12Å; M277-L301 HydrophobicContact SD-CB 4.44Å; M277-L301 HydrophobicContact SD-CD2 4Å; M277-L301 HydrophobicContact SD-CG 4.21Å; M277-R303 VanDerWaalsContact O-CZ 3.27Å; M277-R303 PolarHBondContact O-NE 3.44Å; M277-R303 PolarHBondContact O-NH2 3.41Å; M277-F306 HydrophobicContact CE-CB 3.68Å; M277-F306 HydrophobicContact CE-CD1 3.66Å; M277-F306 HydrophobicContact CE-CD2 3.71Å; M277-F306 HydrophobicContact CE-CE1 4.19Å; M277-F306 HydrophobicContact CE-CE2 4.22Å; M277-F306 HydrophobicContact CE-CG 3.38Å; M277-F306 HydrophobicContact CE-CZ 4.44Å; M277-F306 HydrophobicContact SD-CB 3.61Å; M277-F306 HydrophobicContact SD-CD1 4.23Å; M277-F306 HydrophobicContact SD-CG 3.97Å
278S96.4Very high96.3Very high29 Ų2951.3 Ų51.320%0.20329%0.288CS..Hα-helixtrans-69.1-26.9174.7-580000112.1K274 K275 L276 R303K274-S278 PolarHBondContact O-N 2.85Å; K274-S278 VanDerWaalsContact O-N 3.1Å; K274-S278 PolarHBondContact O-OG 2.86Å; K275-S278 WeakPolarHBondContact O-CB 3.5Å; K275-S278 PolarHBondContact O-N 3.33Å; K275-S278 VanDerWaalsContact O-N 3.16Å; L276-S278 VanDerWaalsContact C-N 3.25Å; L276-S278 PolarHBondContact O-N 2.99Å; S278-R303 PolarHBondContact O-NH2 3.37Å
279A95.9Very high96.3Very high78 Ų7856.1 Ų56.165%0.64531%0.31SS*.Hα-helixtrans-91-52.2172.600000112.2L276 M277 R303L276-A279 PolarHBondContact O-N 3.01Å; M277-A279 VanDerWaalsContact C-N 3.26Å; M277-A279 PolarHBondContact O-N 3.26Å; A279-R303 PolarHBondContact O-NH2 2.98Å
280N95.8Very high96.1Very high73 Ų7357.7 Ų57.739%0.3933%0.325SS..  trans-101.5144.3-172-51.2-82000112L276 M277 L284 R303L276-N280 PolarHBondContact O-N 3.39Å; L276-N280 PolarHBondContact O-ND2 3.1Å; M277-N280 CarbonylContact C-O 3.57Å; M277-N280 WeakPolarHBondContact CA-O 3.48Å; N280-L284 HydrophobicContact CB-CD1 4.28Å; N280-L284 HydrophobicContact CB-CD2 4.26Å; N280-R303 PolarHBondContact O-NH2 2.73Å
281S93.7Very high95.8Very high84 Ų8458 Ų5859%0.58733%0.327SS*.  trans-102.6-15.4179.351.70000114.4
282S95.2Very high95.6Very high68 Ų6857.8 Ų57.848%0.47633%0.326SS..SBendtrans-68.7173.6178.460.30000112.7L284 N302S282-L284 PolarHBondContact O-N 3.13Å; S282-N302 WeakPolarHBondContact O-CA 3.41Å; S282-N302 WeakPolarHBondContact O-CB 3.26Å
283D95.4Very high95.3Very high72 Ų7257.8 Ų57.839%0.38533%0.331SS..  trans-56.2133.8161.6-73.5-21.4000110.2K300 N302D283-K300 HydrophobicContact CB-CD 4.07Å; D283-K300 WeakPolarHBondContact OD2-CE 3.45Å; D283-K300 IonicContact OD2-NZ 2.8Å; D283-K300 PolarHBondContact OD2-NZ 3.38Å; D283-N302 WeakPolarHBondContact OD1-CB 3.34Å; D283-N302 PolarHBondContact OD1-ND2 3.02Å
284L97.2Very high95Very high22 Ų2264.6 Ų64.612%0.11537%0.367CS..EExtended strand (participates in β ladder)trans-122.6137.3173.4-70.4167.7000109L273 L276 M277 N280 S282 K300 L301L273-L284 HydrophobicContact CD1-CB 3.7Å; L273-L284 HydrophobicContact CD1-CD1 4.45Å; L276-L284 HydrophobicContact CB-CD1 3.66Å; M277-L284 HydrophobicContact CB-CD1 4.37Å; M277-L284 HydrophobicContact CG-CD1 3.68Å; N280-L284 HydrophobicContact CB-CD1 4.28Å; N280-L284 HydrophobicContact CB-CD2 4.26Å; S282-L284 PolarHBondContact O-N 3.13Å; L284-K300 CarbonylContact O-C 3.54Å; L284-K300 WeakPolarHBondContact O-CA 3.16Å; L284-K300 WeakPolarHBondContact O-CB 3.45Å; L284-L301 PolarHBondContact N-O 3.35Å; L284-L301 PolarHBondContact O-N 3.42Å
285P96.4Very high94.9Very high84 Ų8466.9 Ų66.955%0.54538%0.38SS..EExtended strand (participates in β ladder)trans-75.2148.6179.731.6-34.9000111.9S299P285-S299 WeakPolarHBondContact CA-O 3.42Å
286L96.8Very high94.8Very high6 Ų665.6 Ų65.63%0.03138%0.379CS..EExtended strand (participates in β ladder)trans-123.3106.9160.9-179.8142.6000107F244 F248 L266 E269 L273 I288 S298 S299F244-L286 HydrophobicContact CD1-CD2 4.49Å; F244-L286 HydrophobicContact CD2-CD1 4.08Å; F244-L286 HydrophobicContact CE2-CD1 3.84Å; F244-L286 HydrophobicContact CZ-CB 4.46Å; F244-L286 HydrophobicContact CZ-CD1 4.21Å; F248-L286 HydrophobicContact CE2-CD2 4.4Å; F248-L286 HydrophobicContact CZ-CD2 3.78Å; L266-L286 HydrophobicContact CD1-CD2 4.4Å; E269-L286 HydrophobicContact CB-CD1 3.96Å; E269-L286 HydrophobicContact CB-CG 4.3Å; L273-L286 HydrophobicContact CD2-CB 4.34Å; L273-L286 HydrophobicContact CD2-CD1 3.98Å; L286-I288 HydrophobicContact CD2-CD1 4.05Å; L286-I288 HydrophobicContact CD2-CG1 4.07Å; L286-S298 CarbonylContact O-C 3.05Å; L286-S298 WeakPolarHBondContact O-CA 3.28Å; L286-S299 PolarHBondContact N-O 2.81Å; L286-S299 PolarHBondContact O-N 2.86Å
287N96Very high94.8Very high94 Ų9461.5 Ų61.550%0.50336%0.357SS..EExtended strand (participates in β ladder)trans-120.7129.9-179.3-64.3-23.5000108.3V297 S298N287-V297 CarbonylContact C-O 3.41Å; N287-V297 WeakPolarHBondContact CA-O 2.95Å; N287-S298 VanDerWaalsContact OD1-CB 3.32Å; N287-S298 WeakPolarHBondContact OD1-CB 3.47Å; N287-S298 PolarHBondContact OD1-OG 3.19Å
288I95.3Very high94.7Very high9 Ų964.1 Ų64.15%0.04638%0.376CS..EExtended strand (participates in β ladder)trans-135.5110.3177.4-35.9-176.3000109.3L266 E269 L286 F291 V297L266-I288 HydrophobicContact CD1-CD1 4Å; E269-I288 HydrophobicContact CB-CD1 4.01Å; E269-I288 HydrophobicContact CB-CG1 4.46Å; E269-I288 HydrophobicContact CG-CD1 3.71Å; E269-I288 HydrophobicContact CG-CG1 3.95Å; L286-I288 HydrophobicContact CD2-CD1 4.05Å; L286-I288 HydrophobicContact CD2-CG1 4.07Å; I288-F291 HydrophobicContact CB-CB 4.21Å; I288-F291 HydrophobicContact CB-CD2 4.03Å; I288-F291 HydrophobicContact CB-CG 4.32Å; I288-F291 HydrophobicContact CD1-CD2 3.98Å; I288-F291 HydrophobicContact CD1-CE2 3.9Å; I288-F291 HydrophobicContact CG2-CB 4.26Å; I288-F291 HydrophobicContact CG2-CD2 3.74Å; I288-F291 HydrophobicContact CG2-CG 4.37Å; I288-V297 HydrophobicContact CB-CG2 3.76Å; I288-V297 HydrophobicContact CD1-CG2 4.3Å; I288-V297 HydrophobicContact CG1-CG2 3.96Å; I288-V297 PolarHBondContact N-O 3.25Å; I288-V297 PolarHBondContact O-N 2.69Å
289E94.5Very high94.7Very high152 Ų15263.7 Ų63.771%0.7137%0.373SS*.EExtended strand (participates in β ladder)trans-74.4144.3179.6-65.6168.6-175.600111.6R265 F291 D296R265-E289 PolarHBondContact NH1-O 2.92Å; R265-E289 PolarHBondContact NH2-O 2.67Å; E289-F291 PolarHBondContact O-N 2.86Å; E289-F291 VanDerWaalsContact O-N 3.14Å; E289-D296 VanDerWaalsContact CA-OD1 3.26Å; E289-D296 WeakPolarHBondContact CA-OD1 3.28Å
290C91.2Very high94.8Very high78 Ų7865.9 Ų65.953%0.52737%0.368SS..EExtended strand (participates in β ladder)trans41.251-177.6-52.50000111.7R265 D296R265-C290 PolarHBondContact NH1-O 2.72Å; C290-D296 PolarHBondContact N-OD1 3.32Å
291F92.9Very high94.8Very high7 Ų762.5 Ų62.53%0.03135%0.35CS..EExtended strand (participates in β ladder)trans-69.9-46.8-166175.2-122.3000112.2F248 L254 V256 A262 R265 L266 I288 E289 I295 V297F248-F291 HydrophobicContact CD2-CD1 4.4Å; F248-F291 AromaticContact CD2-CE1 3.71Å; F248-F291 HydrophobicContact CD2-CE1 3.71Å; F248-F291 HydrophobicContact CD2-CZ 4.32Å; F248-F291 HydrophobicContact CE2-CE1 4.05Å; F248-F291 HydrophobicContact CE2-CZ 4.38Å; L254-F291 HydrophobicContact CD1-CD1 4.03Å; V256-F291 HydrophobicContact CG1-CE1 4.23Å; V256-F291 HydrophobicContact CG1-CZ 3.7Å; V256-F291 HydrophobicContact CG2-CE1 3.65Å; V256-F291 HydrophobicContact CG2-CZ 3.96Å; A262-F291 HydrophobicContact CB-CD2 4.48Å; A262-F291 HydrophobicContact CB-CE2 4.05Å; A262-F291 HydrophobicContact CB-CZ 4.12Å; A262-F291 VanDerWaalsContact O-CE2 3.29Å; A262-F291 WeakPolarHBondContact O-CE2 3.48Å; R265-F291 HydrophobicContact CB-CE2 4.44Å; L266-F291 HydrophobicContact CB-CE2 4.1Å; L266-F291 HydrophobicContact CB-CZ 4.02Å; L266-F291 HydrophobicContact CD2-CZ 4.36Å; I288-F291 HydrophobicContact CB-CB 4.21Å; I288-F291 HydrophobicContact CB-CD2 4.03Å; I288-F291 HydrophobicContact CB-CG 4.32Å; I288-F291 HydrophobicContact CD1-CD2 3.98Å; I288-F291 HydrophobicContact CD1-CE2 3.9Å; I288-F291 HydrophobicContact CG2-CB 4.26Å; I288-F291 HydrophobicContact CG2-CD2 3.74Å; I288-F291 HydrophobicContact CG2-CG 4.37Å; E289-F291 PolarHBondContact O-N 2.86Å; E289-F291 VanDerWaalsContact O-N 3.14Å; F291-I295 PolarHBondContact N-O 2.83Å; F291-V297 HydrophobicContact CB-CG1 4.29Å; F291-V297 HydrophobicContact CB-CG2 3.83Å; F291-V297 HydrophobicContact CD1-CB 4.31Å; F291-V297 HydrophobicContact CD1-CG1 3.65Å; F291-V297 HydrophobicContact CD1-CG2 3.63Å; F291-V297 HydrophobicContact CD2-CG2 4.4Å; F291-V297 HydrophobicContact CE1-CG1 4.41Å; F291-V297 HydrophobicContact CE1-CG2 4.24Å; F291-V297 HydrophobicContact CG-CG1 4.33Å; F291-V297 HydrophobicContact CG-CG2 3.71Å
292M91.3Very high95Very high22 Ų2260.8 Ų60.811%0.10833%0.334CS..EExtended strand (participates in β ladder)trans-159.4138.1176175.2175162.600108.9L254 K259 A262 D294 I295L254-M292 HydrophobicContact CB-SD 4.28Å; L254-M292 HydrophobicContact CD1-CB 4.31Å; L254-M292 HydrophobicContact CD2-CB 4.1Å; L254-M292 HydrophobicContact CD2-CE 4.36Å; L254-M292 HydrophobicContact CD2-CG 3.95Å; L254-M292 HydrophobicContact CD2-SD 4.12Å; K259-M292 HydrophobicContact CB-SD 4.19Å; K259-M292 HydrophobicContact CG-CE 3.62Å; K259-M292 HydrophobicContact CG-CG 4.28Å; K259-M292 HydrophobicContact CG-SD 3.61Å; A262-M292 HydrophobicContact CB-CB 4.38Å; M292-D294 PolarHBondContact O-N 2.91Å; M292-I295 WeakPolarHBondContact O-CB 3.45Å; M292-I295 PolarHBondContact O-N 3.26Å; M292-I295 VanDerWaalsContact O-N 3.12Å
293N90.9Very high95.1Very high107 Ų10759.8 Ų59.857%0.57232%0.32SS*.THydrogen-bonded Turntrans52.438.4-178.6-51.1-12.8000113I295N293-I295 PolarHBondContact O-N 3.32Å
294D91.9Very high95.2Very high146 Ų14658.3 Ų58.378%0.78132%0.322SS*.THydrogen-bonded Turntrans5720.2-178.8-46.1-40.8000115M292M292-D294 PolarHBondContact O-N 2.91Å
295I93.8Very high95.1Very high63 Ų6360.6 Ų60.632%0.32333%0.333SS..EExtended strand (participates in β ladder)trans-94.8128.5173.8-68163.1000109.8Y252 L254 F291 M292 N293Y252-I295 HydrophobicContact CD1-CG2 3.88Å; Y252-I295 HydrophobicContact CG-CG2 4.45Å; L254-I295 HydrophobicContact CD1-CG2 4.26Å; L254-I295 HydrophobicContact CD2-CD1 4.17Å; F291-I295 PolarHBondContact N-O 2.83Å; M292-I295 WeakPolarHBondContact O-CB 3.45Å; M292-I295 PolarHBondContact O-N 3.26Å; M292-I295 VanDerWaalsContact O-N 3.12Å; N293-I295 PolarHBondContact O-N 3.32Å
296D95.8Very high95.2Very high94 Ų9456.7 Ų56.750%0.50331%0.308SS..EExtended strand (participates in β ladder)trans-77.5137.7167.5-55.5-35.6000110.5E289 C290E289-D296 VanDerWaalsContact CA-OD1 3.26Å; E289-D296 WeakPolarHBondContact CA-OD1 3.28Å; C290-D296 PolarHBondContact N-OD1 3.32Å
297V96.7Very high95.2Very high2 Ų258.5 Ų58.51%0.01232%0.316CS..EExtended strand (participates in β ladder)trans-112.5135.8172.8-61.60000110.6F248 Y252 L254 N287 I288 F291F248-V297 HydrophobicContact CD1-CB 4.35Å; F248-V297 HydrophobicContact CD1-CG1 4.43Å; F248-V297 HydrophobicContact CD2-CB 4.34Å; F248-V297 HydrophobicContact CD2-CG1 4.21Å; F248-V297 HydrophobicContact CD2-CG2 4.25Å; F248-V297 HydrophobicContact CE1-CB 4.03Å; F248-V297 HydrophobicContact CE1-CG2 4.43Å; F248-V297 HydrophobicContact CE2-CB 3.99Å; F248-V297 HydrophobicContact CE2-CG1 4.35Å; F248-V297 HydrophobicContact CE2-CG2 3.62Å; F248-V297 HydrophobicContact CG-CG1 4.24Å; F248-V297 HydrophobicContact CZ-CB 3.83Å; F248-V297 HydrophobicContact CZ-CG2 3.72Å; Y252-V297 HydrophobicContact CD1-CG1 4.46Å; Y252-V297 HydrophobicContact CD2-CB 4.19Å; Y252-V297 HydrophobicContact CD2-CG1 3.65Å; Y252-V297 HydrophobicContact CE2-CB 3.86Å; Y252-V297 HydrophobicContact CE2-CG1 3.83Å; Y252-V297 HydrophobicContact CG-CG1 4Å; L254-V297 HydrophobicContact CD1-CG1 3.74Å; N287-V297 CarbonylContact C-O 3.41Å; N287-V297 WeakPolarHBondContact CA-O 2.95Å; I288-V297 HydrophobicContact CB-CG2 3.76Å; I288-V297 HydrophobicContact CD1-CG2 4.3Å; I288-V297 HydrophobicContact CG1-CG2 3.96Å; I288-V297 PolarHBondContact N-O 3.25Å; I288-V297 PolarHBondContact O-N 2.69Å; F291-V297 HydrophobicContact CB-CG1 4.29Å; F291-V297 HydrophobicContact CB-CG2 3.83Å; F291-V297 HydrophobicContact CD1-CB 4.31Å; F291-V297 HydrophobicContact CD1-CG1 3.65Å; F291-V297 HydrophobicContact CD1-CG2 3.63Å; F291-V297 HydrophobicContact CD2-CG2 4.4Å; F291-V297 HydrophobicContact CE1-CG1 4.41Å; F291-V297 HydrophobicContact CE1-CG2 4.24Å; F291-V297 HydrophobicContact CG-CG1 4.33Å; F291-V297 HydrophobicContact CG-CG2 3.71Å
298S96.4Very high95.3Very high57 Ų5760.8 Ų60.840%0.39932%0.324SS..EExtended strand (participates in β ladder)trans-137.3130.5177.61780000109.8K251 Y252 L286 N287K251-S298 PolarHBondContact NZ-O 3.34Å; Y252-S298 PolarHBondContact OH-N 2.9Å; Y252-S298 PolarHBondContact OH-O 2.87Å; Y252-S298 VanDerWaalsContact OH-O 3.12Å; L286-S298 CarbonylContact O-C 3.05Å; L286-S298 WeakPolarHBondContact O-CA 3.28Å; N287-S298 VanDerWaalsContact OD1-CB 3.32Å; N287-S298 WeakPolarHBondContact OD1-CB 3.47Å; N287-S298 PolarHBondContact OD1-OG 3.19Å
299S96.8Very high95.4Very high20 Ų2063 Ų6314%0.1434%0.335CS..EExtended strand (participates in β ladder)trans-149.6-177.2174.3-165.40000110.4E247 P285 L286E247-S299 VanDerWaalsContact CD-OG 3.28Å; E247-S299 PolarHBondContact OE1-OG 3.2Å; E247-S299 WeakPolarHBondContact OE2-CB 3.5Å; E247-S299 PolarHBondContact OE2-OG 3.01Å; P285-S299 WeakPolarHBondContact CA-O 3.42Å; L286-S299 PolarHBondContact N-O 2.81Å; L286-S299 PolarHBondContact O-N 2.86Å
300K96.3Very high95.5Very high124 Ų12455.8 Ų55.854%0.53930%0.301SS..EExtended strand (participates in β ladder)trans-148.9150.8176.163.3175.2-170.6159.70111.4D283 L284D283-K300 HydrophobicContact CB-CD 4.07Å; D283-K300 WeakPolarHBondContact OD2-CE 3.45Å; D283-K300 IonicContact OD2-NZ 2.8Å; D283-K300 PolarHBondContact OD2-NZ 3.38Å; L284-K300 CarbonylContact O-C 3.54Å; L284-K300 WeakPolarHBondContact O-CA 3.16Å; L284-K300 WeakPolarHBondContact O-CB 3.45Å
301L97.2Very high95.8Very high2 Ų254.4 Ų54.41%0.0130%0.295CS..EExtended strand (participates in β ladder)trans-144.1147.8175.5-162.569.9000110.4L240 F244 L273 M277 L284 L305 F306 M309L240-L301 HydrophobicContact CD2-CD2 3.26Å; F244-L301 HydrophobicContact CZ-CB 4.25Å; F244-L301 HydrophobicContact CZ-CD2 4.42Å; L273-L301 HydrophobicContact CD2-CB 4.08Å; L273-L301 HydrophobicContact CD2-CD2 4.3Å; M277-L301 HydrophobicContact CE-CD2 4.12Å; M277-L301 HydrophobicContact SD-CB 4.44Å; M277-L301 HydrophobicContact SD-CD2 4Å; M277-L301 HydrophobicContact SD-CG 4.21Å; L284-L301 PolarHBondContact N-O 3.35Å; L284-L301 PolarHBondContact O-N 3.42Å; L301-L305 HydrophobicContact CD1-CB 4.26Å; L301-L305 HydrophobicContact CD1-CD2 3.78Å; L301-L305 HydrophobicContact CD1-CG 3.97Å; L301-F306 HydrophobicContact CD2-CB 4.05Å; L301-M309 HydrophobicContact CD1-CE 3.93Å; L301-M309 HydrophobicContact CD2-CE 3.9Å
302N96.8Very high95.9Very high48 Ų4856.8 Ų56.826%0.25732%0.322SS..  trans-114.7163.6171.959.368.6000111.3S282 D283 G304 L305 F306S282-N302 WeakPolarHBondContact O-CA 3.41Å; S282-N302 WeakPolarHBondContact O-CB 3.26Å; D283-N302 WeakPolarHBondContact OD1-CB 3.34Å; D283-N302 PolarHBondContact OD1-ND2 3.02Å; N302-G304 VanDerWaalsContact C-N 3.3Å; N302-G304 PolarHBondContact O-N 3.18Å; N302-G304 PolarHBondContact OD1-N 3.23Å; N302-L305 PolarHBondContact O-N 3.31Å; N302-L305 PolarHBondContact OD1-N 3.3Å; N302-L305 VanDerWaalsContact OD1-N 3.11Å; N302-F306 PolarHBondContact O-N 2.88Å; N302-F306 VanDerWaalsContact O-N 3.16Å
303R97.4Very high96.2Very high47 Ų4757.1 Ų57.118%0.17732%0.324CS..Hα-helixtrans-56-42-178-177.9-173-58.3166.30.5112.8M277 S278 A279 N280 F306 E307M277-R303 VanDerWaalsContact O-CZ 3.27Å; M277-R303 PolarHBondContact O-NE 3.44Å; M277-R303 PolarHBondContact O-NH2 3.41Å; S278-R303 PolarHBondContact O-NH2 3.37Å; A279-R303 PolarHBondContact O-NH2 2.98Å; N280-R303 PolarHBondContact O-NH2 2.73Å; R303-F306 WeakPolarHBondContact O-CB 3.4Å; R303-F306 PolarHBondContact O-N 3.43Å; R303-E307 VanDerWaalsContact CG-CD 3.49Å; R303-E307 HydrophobicContact CG-CG 4.1Å; R303-E307 WeakPolarHBondContact O-CB 3.43Å; R303-E307 WeakPolarHBondContact O-CG 3.16Å; R303-E307 PolarHBondContact O-N 3.26Å
304G97.1Very high96.4Very high41 Ų4152.3 Ų52.342%0.42330%0.298SS..Hα-helixtrans-61.3-49.5-175.400000112.5N302 F306 E307 E308N302-G304 VanDerWaalsContact C-N 3.3Å; N302-G304 PolarHBondContact O-N 3.18Å; N302-G304 PolarHBondContact OD1-N 3.23Å; G304-F306 VanDerWaalsContact C-N 3.33Å; G304-F306 PolarHBondContact O-N 2.91Å; G304-E307 PolarHBondContact O-N 3.07Å; G304-E308 WeakPolarHBondContact O-CB 3.23Å; G304-E308 PolarHBondContact O-N 3.36Å
305L96.7Very high96.6Very high69 Ų6948.2 Ų48.236%0.36129%0.285SS..Hα-helixtrans-67.4-33.7177.3-177.355.6000112.3L301 N302 M309L301-L305 HydrophobicContact CD1-CB 4.26Å; L301-L305 HydrophobicContact CD1-CD2 3.78Å; L301-L305 HydrophobicContact CD1-CG 3.97Å; N302-L305 PolarHBondContact O-N 3.31Å; N302-L305 PolarHBondContact OD1-N 3.3Å; N302-L305 VanDerWaalsContact OD1-N 3.11Å; L305-M309 HydrophobicContact CD1-CG 4.5Å; L305-M309 HydrophobicContact CG-CE 4.44Å; L305-M309 WeakPolarHBondContact O-CG 3.35Å; L305-M309 PolarHBondContact O-N 2.77Å
306F97.9Very high96.7Very high3 Ų348.9 Ų48.91%0.01329%0.285CS..Hα-helixtrans-63.8-46171.9166.4-114000112.5F236 L240 K274 M277 L301 N302 R303 G304 E308 M309 C310 I347F236-F306 HydrophobicContact CB-CE2 4.23Å; F236-F306 HydrophobicContact CB-CZ 4.02Å; F236-F306 HydrophobicContact CD1-CE2 4.38Å; F236-F306 AromaticContact CD1-CZ 3.87Å; F236-F306 HydrophobicContact CD1-CZ 3.87Å; F236-F306 HydrophobicContact CG-CZ 4.37Å; L240-F306 HydrophobicContact CD1-CD2 4.21Å; L240-F306 HydrophobicContact CD1-CE2 3.94Å; L240-F306 HydrophobicContact CD2-CD2 3.66Å; L240-F306 HydrophobicContact CD2-CE2 4.15Å; L240-F306 HydrophobicContact CG-CD2 3.97Å; L240-F306 HydrophobicContact CG-CE2 3.93Å; K274-F306 HydrophobicContact CD-CZ 4.37Å; K274-F306 HydrophobicContact CG-CE1 4.4Å; K274-F306 HydrophobicContact CG-CZ 3.86Å; M277-F306 HydrophobicContact CE-CB 3.68Å; M277-F306 HydrophobicContact CE-CD1 3.66Å; M277-F306 HydrophobicContact CE-CD2 3.71Å; M277-F306 HydrophobicContact CE-CE1 4.19Å; M277-F306 HydrophobicContact CE-CE2 4.22Å; M277-F306 HydrophobicContact CE-CG 3.38Å; M277-F306 HydrophobicContact CE-CZ 4.44Å; M277-F306 HydrophobicContact SD-CB 3.61Å; M277-F306 HydrophobicContact SD-CD1 4.23Å; M277-F306 HydrophobicContact SD-CG 3.97Å; L301-F306 HydrophobicContact CD2-CB 4.05Å; N302-F306 PolarHBondContact O-N 2.88Å; N302-F306 VanDerWaalsContact O-N 3.16Å; R303-F306 WeakPolarHBondContact O-CB 3.4Å; R303-F306 PolarHBondContact O-N 3.43Å; G304-F306 VanDerWaalsContact C-N 3.33Å; G304-F306 PolarHBondContact O-N 2.91Å; F306-E308 VanDerWaalsContact C-N 3.34Å; F306-M309 PolarHBondContact O-N 3.07Å; F306-C310 WeakPolarHBondContact CE2-SG 3.41Å; F306-C310 WeakPolarHBondContact O-CB 2.8Å; F306-C310 PolarHBondContact O-N 3.03Å; F306-C310 PolarHBondContact O-SG 3.04Å; F306-I347 HydrophobicContact CE1-CG2 4.48Å
307E97.1Very high96.8Very high44 Ų4444.4 Ų44.421%0.20626%0.261CS..Hα-helixtrans-68.5-32.9179-71.6175.9158.400111.7R303 G304 C310 A311 L314 A349R303-E307 VanDerWaalsContact CG-CD 3.49Å; R303-E307 HydrophobicContact CG-CG 4.1Å; R303-E307 WeakPolarHBondContact O-CB 3.43Å; R303-E307 WeakPolarHBondContact O-CG 3.16Å; R303-E307 PolarHBondContact O-N 3.26Å; G304-E307 PolarHBondContact O-N 3.07Å; E307-C310 PolarHBondContact O-N 3.12Å; E307-A311 PolarHBondContact O-N 3.11Å; E307-L314 HydrophobicContact CB-CD1 4.34Å; E307-L314 WeakPolarHBondContact O-CD1 3.43Å; E307-A349 HydrophobicContact CG-CB 3.95Å; E307-A349 WeakPolarHBondContact OE1-CB 3.17Å; E307-A349 PolarHBondContact OE1-N 3.16Å; E307-A349 VanDerWaalsContact OE1-N 3.1Å
308E97.3Very high96.7Very high141 Ų14147.1 Ų47.166%0.65927%0.274SS*.Hα-helixtrans-62-52.5169.4-175.8179.8-178.500111.8G304 F306 C310 A311G304-E308 WeakPolarHBondContact O-CB 3.23Å; G304-E308 PolarHBondContact O-N 3.36Å; F306-E308 VanDerWaalsContact C-N 3.34Å; E308-C310 PolarHBondContact O-N 2.78Å; E308-A311 VanDerWaalsContact O-CB 3.24Å; E308-A311 WeakPolarHBondContact O-CB 3.32Å; E308-A311 PolarHBondContact O-N 2.7Å; E308-A311 VanDerWaalsContact O-N 3.09Å
309M97.7Very high96.7Very high56 Ų5646.4 Ų46.428%0.27628%0.275SS..Hα-helixtrans-59.3-30.5176.3-71.3-172.1-63.100112.7I239 L240 H243 L301 L305 F306I239-M309 HydrophobicContact CG2-CB 3.88Å; L240-M309 HydrophobicContact CD2-CE 4.49Å; H243-M309 HydrophobicContact CB-SD 4.15Å; H243-M309 PolarHBondContact ND1-SD 2.89Å; L301-M309 HydrophobicContact CD1-CE 3.93Å; L301-M309 HydrophobicContact CD2-CE 3.9Å; L305-M309 HydrophobicContact CD1-CG 4.5Å; L305-M309 HydrophobicContact CG-CE 4.44Å; L305-M309 WeakPolarHBondContact O-CG 3.35Å; L305-M309 PolarHBondContact O-N 2.77Å; F306-M309 PolarHBondContact O-N 3.07Å
310C97.4Very high96.7Very high0 Ų046 Ų460%027%0.272CS..THydrogen-bonded Turntrans-88.14.2179.7-62.80000114.5F236 I239 F306 E307 E308 G312 L313 L314F236-C310 HydrophobicContact CD1-CB 3.85Å; F236-C310 HydrophobicContact CE1-CB 3.83Å; I239-C310 HydrophobicContact CD1-CB 4.38Å; F306-C310 WeakPolarHBondContact CE2-SG 3.41Å; F306-C310 WeakPolarHBondContact O-CB 2.8Å; F306-C310 PolarHBondContact O-N 3.03Å; F306-C310 PolarHBondContact O-SG 3.04Å; E307-C310 PolarHBondContact O-N 3.12Å; E308-C310 PolarHBondContact O-N 2.78Å; C310-G312 PolarHBondContact O-N 3.35Å; C310-L313 PolarHBondContact O-N 3.01Å; C310-L314 HydrophobicContact CB-CD1 4.28Å; C310-L314 HydrophobicContact CB-CG 4.26Å; C310-L314 WeakPolarHBondContact O-CG 3.35Å; C310-L314 PolarHBondContact O-N 3.39Å
311A96.3Very high96.8Very high50 Ų5040 Ų4041%0.41325%0.246SC..Hα-helixtrans-51.4-36.4-174.300000114.2E307 E308 L314 A315E307-A311 PolarHBondContact O-N 3.11Å; E308-A311 VanDerWaalsContact O-CB 3.24Å; E308-A311 WeakPolarHBondContact O-CB 3.32Å; E308-A311 PolarHBondContact O-N 2.7Å; E308-A311 VanDerWaalsContact O-N 3.09Å; A311-L314 PolarHBondContact O-N 2.91Å; A311-A315 PolarHBondContact O-N 2.89Å
312G95.8Very high96.8Very high57 Ų5745.4 Ų45.459%0.58827%0.271SS*.Hα-helixtrans-67.4-37.4176.500000114.5C310C310-G312 PolarHBondContact O-N 3.35Å
313L96.3Very high96.7Very high28 Ų2845 Ų4515%0.14727%0.272CS..Hα-helixtrans-73.7-41172.9-64.3-177.6000111L231 D235 F236 I239 C310 A315 K316L231-L313 HydrophobicContact CD1-CB 3.96Å; L231-L313 HydrophobicContact CD1-CD2 4.15Å; D235-L313 VanDerWaalsContact C-CD1 3.48Å; D235-L313 HydrophobicContact CB-CD1 3.71Å; D235-L313 HydrophobicContact CB-CD2 4.21Å; D235-L313 WeakPolarHBondContact O-CD1 3.41Å; F236-L313 HydrophobicContact CD1-CD1 4.24Å; F236-L313 HydrophobicContact CD2-CD1 4.13Å; F236-L313 HydrophobicContact CE1-CB 4.16Å; F236-L313 HydrophobicContact CE1-CD1 4.3Å; F236-L313 HydrophobicContact CE2-CB 4.44Å; F236-L313 HydrophobicContact CE2-CD1 4.18Å; F236-L313 HydrophobicContact CG-CD1 4.14Å; F236-L313 HydrophobicContact CZ-CB 3.9Å; F236-L313 HydrophobicContact CZ-CD1 4.25Å; I239-L313 HydrophobicContact CD1-CD1 3.53Å; I239-L313 HydrophobicContact CD1-CG 3.91Å; I239-L313 HydrophobicContact CG1-CD1 4.42Å; C310-L313 PolarHBondContact O-N 3.01Å; L313-A315 PolarHBondContact O-N 3.09Å; L313-K316 HydrophobicContact CD2-CD 4.29Å; L313-K316 WeakPolarHBondContact O-CB 3.42Å; L313-K316 PolarHBondContact O-N 3.29Å
314L96.6Very high96.7Very high7 Ų742.7 Ų42.74%0.03726%0.263CS..Hα-helixtrans-60.9-29.7177.9-67.8175.2000112.2F236 E307 C310 A311 V317 A349 I350 R353F236-L314 HydrophobicContact CE1-CD2 3.98Å; F236-L314 HydrophobicContact CE1-CG 4.33Å; F236-L314 HydrophobicContact CZ-CD2 4.24Å; E307-L314 HydrophobicContact CB-CD1 4.34Å; E307-L314 WeakPolarHBondContact O-CD1 3.43Å; C310-L314 HydrophobicContact CB-CD1 4.28Å; C310-L314 HydrophobicContact CB-CG 4.26Å; C310-L314 WeakPolarHBondContact O-CG 3.35Å; C310-L314 PolarHBondContact O-N 3.39Å; A311-L314 PolarHBondContact O-N 2.91Å; L314-V317 WeakPolarHBondContact O-CB 3.14Å; L314-V317 WeakPolarHBondContact O-CG2 3.2Å; L314-A349 HydrophobicContact CD1-CB 3.87Å; L314-A349 HydrophobicContact CD2-CB 3.86Å; L314-I350 HydrophobicContact CD2-CD1 3.63Å; L314-I350 HydrophobicContact CD2-CG1 4.3Å; L314-R353 WeakPolarHBondContact O-CD 3.47Å; L314-R353 PolarHBondContact O-NE 3.36Å
315A95.3Very high96.7Very high60 Ų6041.8 Ų41.850%0.49625%0.248SC..Hα-helixtrans-68.9-29.9173.700000114A311 L313 V317A311-A315 PolarHBondContact O-N 2.89Å; L313-A315 PolarHBondContact O-N 3.09Å; A315-V317 VanDerWaalsContact C-N 3.27Å; A315-V317 PolarHBondContact O-N 3.4Å
316K96.1Very high96.6Very high76 Ų7645.8 Ų45.833%0.3327%0.265SS..Hα-helixtrans-65.7-28.6178.5-71.1172.3142.4-128.70113.2D228 D230 L231 L313 E318 G319 P320D228-K316 IonicContact OD1-NZ 2.99Å; D228-K316 PolarHBondContact OD1-NZ 2.89Å; D228-K316 WeakPolarHBondContact OD2-CD 3.39Å; D228-K316 WeakPolarHBondContact OD2-CE 3.27Å; D228-K316 IonicContact OD2-NZ 3.9Å; D228-K316 PolarHBondContact OD2-NZ 3.28Å; D230-K316 PolarHBondContact O-NZ 3.47Å; L231-K316 HydrophobicContact CB-CD 4.4Å; L231-K316 HydrophobicContact CD1-CD 4.17Å; L231-K316 HydrophobicContact CD2-CB 3.83Å; L313-K316 HydrophobicContact CD2-CD 4.29Å; L313-K316 WeakPolarHBondContact O-CB 3.42Å; L313-K316 PolarHBondContact O-N 3.29Å; K316-E318 PolarHBondContact O-N 2.91Å; K316-E318 VanDerWaalsContact O-N 3.07Å; K316-G319 PolarHBondContact O-N 3.47Å; K316-P320 WeakPolarHBondContact O-CD 3.14Å
317V96.8Very high96.5Very high0 Ų048.1 Ų48.10%028%0.276CS..THydrogen-bonded Turntrans-53.7-33.2-172.9-179.70000112.9Y208 L231 L314 A315 L321 I350 R353 I354Y208-V317 VanDerWaalsContact CE1-O 3.22Å; Y208-V317 WeakPolarHBondContact CE1-O 3.45Å; Y208-V317 PolarHBondContact OH-O 2.96Å; L231-V317 HydrophobicContact CD2-CG2 4.23Å; L314-V317 WeakPolarHBondContact O-CB 3.14Å; L314-V317 WeakPolarHBondContact O-CG2 3.2Å; A315-V317 VanDerWaalsContact C-N 3.27Å; A315-V317 PolarHBondContact O-N 3.4Å; V317-L321 WeakPolarHBondContact O-CG 3.47Å; V317-I350 HydrophobicContact CG2-CD1 3.58Å; V317-R353 HydrophobicContact CG1-CB 4.35Å; V317-I354 HydrophobicContact CG1-CG1 4.12Å
318E95.9Very high96.4Very high59 Ų5947.3 Ų47.328%0.27627%0.274SS..Hα-helixtrans-81.7-18.1-175.8-68.2168-126.200113K316 L321 H322 R353K316-E318 PolarHBondContact O-N 2.91Å; K316-E318 VanDerWaalsContact O-N 3.07Å; E318-L321 PolarHBondContact O-N 3.46Å; E318-H322 PolarHBondContact O-CD2 2.9Å; E318-H322 VanDerWaalsContact O-CD2 3.26Å; E318-H322 PolarHBondContact O-N 2.67Å; E318-R353 IonicContact OE1-CZ 3.17Å; E318-R353 IonicContact OE1-NH1 3.86Å; E318-R353 PolarHBondContact OE1-NH1 3.13Å
319G96Very high96.4Very high42 Ų4249.5 Ų49.543%0.43328%0.281SS..Hα-helixtrans-61.8-58.9-176.900000113.9K316 L321 H322 S323K316-G319 PolarHBondContact O-N 3.47Å; G319-L321 VanDerWaalsContact C-N 3.25Å; G319-L321 PolarHBondContact O-N 3.36Å; G319-H322 PolarHBondContact O-N 3.04Å; G319-S323 PolarHBondContact O-N 3.46Å
320P96.7Very high96.3Very high11 Ų1149.1 Ų49.17%0.07128%0.28CS..Hα-helixtrans-59-32.2173.4-31.340.3000114.2Y208 V210 A226 D228 K316 S323 V324Y208-P320 HydrophobicContact CD1-CB 4.22Å; Y208-P320 HydrophobicContact CD1-CG 3.71Å; Y208-P320 HydrophobicContact CE1-CB 3.86Å; Y208-P320 HydrophobicContact CE1-CG 3.67Å; V210-P320 HydrophobicContact CG2-CB 3.85Å; A226-P320 HydrophobicContact CB-CB 4.06Å; D228-P320 HydrophobicContact CB-CG 4.21Å; K316-P320 WeakPolarHBondContact O-CD 3.14Å; P320-S323 PolarHBondContact O-N 2.69Å; P320-V324 PolarHBondContact O-N 3.04Å
321L97.6Very high96.2Very high0 Ų056 Ų560%031%0.31CS..Hα-helixtrans-65.2-47.3175.1-59.3178.6000111.4V201 Y208 V210 V317 E318 G319 S323 V324 M325 I354 F357 F358V201-L321 HydrophobicContact CG2-CD2 4.2Å; Y208-L321 WeakPolarHBondContact OH-CG 3.48Å; V210-L321 HydrophobicContact CG1-CD2 4.03Å; V210-L321 HydrophobicContact CG2-CD2 3.86Å; V317-L321 WeakPolarHBondContact O-CG 3.47Å; E318-L321 PolarHBondContact O-N 3.46Å; G319-L321 VanDerWaalsContact C-N 3.25Å; G319-L321 PolarHBondContact O-N 3.36Å; L321-S323 VanDerWaalsContact C-N 3.32Å; L321-S323 PolarHBondContact O-N 2.77Å; L321-V324 WeakPolarHBondContact O-CG2 3.31Å; L321-M325 WeakPolarHBondContact O-CG 3.5Å; L321-M325 PolarHBondContact O-N 2.87Å; L321-I354 HydrophobicContact CD1-CG1 4.27Å; L321-F357 HydrophobicContact CB-CD1 3.85Å; L321-F357 HydrophobicContact CB-CD2 4.13Å; L321-F357 HydrophobicContact CB-CE1 3.68Å; L321-F357 HydrophobicContact CB-CE2 3.95Å; L321-F357 HydrophobicContact CB-CG 4.09Å; L321-F357 HydrophobicContact CB-CZ 3.73Å; L321-F357 HydrophobicContact CD1-CB 3.96Å; L321-F357 HydrophobicContact CD1-CD1 3.99Å; L321-F357 HydrophobicContact CD1-CD2 4.38Å; L321-F357 HydrophobicContact CD1-CG 3.84Å; L321-F357 HydrophobicContact CG-CD1 4.45Å; L321-F358 HydrophobicContact CD2-CE2 3.79Å; L321-F358 HydrophobicContact CD2-CZ 3.93Å
322H97.4Very high96.2Very high114 Ų11457.5 Ų57.553%0.52831%0.307SS..Hα-helixtrans-57.7-45.9171.6-86.6-75.4000111.5E318 G319 V324 M325 E326 F357E318-H322 PolarHBondContact O-CD2 2.9Å; E318-H322 VanDerWaalsContact O-CD2 3.26Å; E318-H322 PolarHBondContact O-N 2.67Å; G319-H322 PolarHBondContact O-N 3.04Å; H322-V324 PolarHBondContact O-N 2.82Å; H322-M325 PolarHBondContact O-N 3.38Å; H322-E326 PolarHBondContact O-N 3.27Å; H322-F357 AromaticContact CD2-CE2 3.69Å; H322-F357 AromaticContact CE1-CE2 3.88Å; H322-F357 AromaticContact CG-CE2 3.85Å; H322-F357 AromaticContact ND1-CE2 3.97Å; H322-F357 AromaticContact NE2-CE2 3.7Å
323S95.8Very high96.1Very high39 Ų3961.5 Ų61.527%0.27331%0.311SS..Hα-helixtrans-63.3-42.3-175.4-166.90000113.1G319 P320 L321 M325 E326 Q327G319-S323 PolarHBondContact O-N 3.46Å; P320-S323 PolarHBondContact O-N 2.69Å; L321-S323 VanDerWaalsContact C-N 3.32Å; L321-S323 PolarHBondContact O-N 2.77Å; S323-M325 VanDerWaalsContact C-N 3.32Å; S323-M325 PolarHBondContact O-N 2.76Å; S323-E326 PolarHBondContact O-N 2.91Å; S323-Q327 WeakPolarHBondContact O-CB 3.25Å; S323-Q327 WeakPolarHBondContact O-CG 3.46Å; S323-Q327 PolarHBondContact O-N 3.07Å; S323-Q327 PolarHBondContact O-NE2 2.88Å; S323-Q327 PolarHBondContact OG-NE2 2.92Å
324V96Very high96.1Very high0 Ų064.1 Ų64.10%033%0.325CS..Hα-helixtrans-67.7-31.8177-63.90000113.2V210 V212 A226 P320 L321 H322 T328V210-V324 HydrophobicContact CB-CG1 4.08Å; V210-V324 HydrophobicContact CG1-CB 4.45Å; V210-V324 HydrophobicContact CG1-CG1 3.94Å; V210-V324 HydrophobicContact CG1-CG2 3.69Å; V212-V324 HydrophobicContact CG2-CB 3.67Å; V212-V324 HydrophobicContact CG2-CG1 4.41Å; V212-V324 HydrophobicContact CG2-CG2 3.68Å; A226-V324 HydrophobicContact CB-CG1 3.57Å; P320-V324 PolarHBondContact O-N 3.04Å; L321-V324 WeakPolarHBondContact O-CG2 3.31Å; H322-V324 PolarHBondContact O-N 2.82Å; V324-T328 WeakPolarHBondContact O-CB 3.43Å; V324-T328 WeakPolarHBondContact O-CG2 3.33Å; V324-T328 PolarHBondContact O-N 2.66Å; V324-T328 PolarHBondContact O-OG1 3.28Å
325M97.1Very high96.2Very high21 Ų2163.9 Ų63.910%0.10332%0.324CS..Hα-helixtrans-70.2-41.9177.4-63.3-53.1-66.300111.2L321 H322 S323 T328 K329 L330 K331 K332 I335 F357 F358L321-M325 WeakPolarHBondContact O-CG 3.5Å; L321-M325 PolarHBondContact O-N 2.87Å; H322-M325 PolarHBondContact O-N 3.38Å; S323-M325 VanDerWaalsContact C-N 3.32Å; S323-M325 PolarHBondContact O-N 2.76Å; M325-T328 PolarHBondContact O-OG1 2.71Å; M325-K329 WeakPolarHBondContact O-CA 3.47Å; M325-K329 PolarHBondContact O-N 2.79Å; M325-L330 HydrophobicContact CE-CB 4.34Å; M325-L330 WeakPolarHBondContact CE-O 3.25Å; M325-K331 WeakPolarHBondContact CE-O 3.44Å; M325-K332 HydrophobicContact CE-CG 4.45Å; M325-I335 HydrophobicContact CE-CD1 3.82Å; M325-I335 HydrophobicContact SD-CD1 3.79Å; M325-F357 HydrophobicContact CG-CE1 4.04Å; M325-F357 HydrophobicContact CG-CZ 4.07Å; M325-F358 HydrophobicContact SD-CE1 4.07Å
326E96.4Very high96.3Very high153 Ų15367.3 Ų67.372%0.71533%0.325SS*.Hα-helixtrans-63.6-46.3173.5-176.7176-157.800112H322 S323 T328 K329H322-E326 PolarHBondContact O-N 3.27Å; S323-E326 PolarHBondContact O-N 2.91Å; E326-T328 VanDerWaalsContact C-N 3.35Å; E326-T328 PolarHBondContact O-N 3.02Å; E326-K329 WeakPolarHBondContact O-CG 3.45Å; E326-K329 PolarHBondContact O-N 2.89Å
327Q94.9Very high96.3Very high52 Ų5264 Ų6424%0.24331%0.312CS..Hα-helixtrans-62-38.7179.4-73.4175.961.100112.9A224 A225 S323 N423A224-Q327 HydrophobicContact CB-CB 3.83Å; A225-Q327 PolarHBondContact O-NE2 3.09Å; A225-Q327 PolarHBondContact O-OE1 2.82Å; S323-Q327 WeakPolarHBondContact O-CB 3.25Å; S323-Q327 WeakPolarHBondContact O-CG 3.46Å; S323-Q327 PolarHBondContact O-N 3.07Å; S323-Q327 PolarHBondContact O-NE2 2.88Å; S323-Q327 PolarHBondContact OG-NE2 2.92Å; Q327-N423 PolarHBondContact OE1-ND2 2.78Å
328T96.1Very high96.4Very high28 Ų2864 Ų6417%0.17231%0.312CS..Hα-helixtrans-86.4-21.2179.8560000114.1V212 L223 A224 V324 M325 E326 L330V212-T328 HydrophobicContact CB-CG2 3.97Å; V212-T328 HydrophobicContact CG1-CG2 4.09Å; V212-T328 HydrophobicContact CG2-CG2 4.27Å; L223-T328 HydrophobicContact CB-CG2 3.88Å; A224-T328 HydrophobicContact CB-CG2 3.57Å; V324-T328 WeakPolarHBondContact O-CB 3.43Å; V324-T328 WeakPolarHBondContact O-CG2 3.33Å; V324-T328 PolarHBondContact O-N 2.66Å; V324-T328 PolarHBondContact O-OG1 3.28Å; M325-T328 PolarHBondContact O-OG1 2.71Å; E326-T328 VanDerWaalsContact C-N 3.35Å; E326-T328 PolarHBondContact O-N 3.02Å; T328-L330 PolarHBondContact O-N 2.78Å
329K95.8Very high96.5Very high186 Ų18661.3 Ų61.381%0.80930%0.299SS*.THydrogen-bonded Turntrans58.319.8-173.8-51.7-178.8-177.1-1790114M325 E326M325-K329 WeakPolarHBondContact O-CA 3.47Å; M325-K329 PolarHBondContact O-N 2.79Å; E326-K329 WeakPolarHBondContact O-CG 3.45Å; E326-K329 PolarHBondContact O-N 2.89Å
330L96.1Very high96.6Very high48 Ų4859.5 Ų59.525%0.25128%0.28SS..  trans-79.1158.8172.6-66.3172.8000110.4I197 V212 L223 M325 T328 D334I197-L330 HydrophobicContact CG1-CD1 4.37Å; I197-L330 HydrophobicContact CG2-CD1 3.95Å; V212-L330 HydrophobicContact CG1-CD1 4.05Å; L223-L330 HydrophobicContact CD1-CD1 4.14Å; M325-L330 HydrophobicContact CE-CB 4.34Å; M325-L330 WeakPolarHBondContact CE-O 3.25Å; T328-L330 PolarHBondContact O-N 2.78Å; L330-D334 HydrophobicContact CB-CB 4.47Å; L330-D334 HydrophobicContact CD2-CB 4.27Å
331K95.9Very high96.6Very high144 Ų14459 Ų5963%0.62628%0.277SS*.  trans-96.3168.7170.9-47.3-179.7-179.5176.50110.5M325 E333 D334M325-K331 WeakPolarHBondContact CE-O 3.44Å; K331-E333 WeakPolarHBondContact CB-OE2 3.15Å; K331-E333 PolarHBondContact O-N 3.4Å; K331-D334 WeakPolarHBondContact CB-OD2 3.4Å; K331-D334 PolarHBondContact N-OD2 3.27Å; K331-D334 PolarHBondContact O-N 3.37Å
332K94.9Very high96.5Very high82 Ų8259.4 Ų59.436%0.35728%0.28SS..SBendtrans-67.9-27179.2-64.9-179.6-178.2-176.80111.5M325 I335 F357 K360M325-K332 HydrophobicContact CE-CG 4.45Å; K332-I335 PolarHBondContact O-N 3.06Å; K332-F357 WeakPolarHBondContact CD-O 3.48Å; K332-F357 WeakPolarHBondContact CE-O 3.45Å; K332-F357 PolarHBondContact NZ-O 3.19Å; K332-K360 WeakPolarHBondContact O-CE 3.45Å
333E95.3Very high96.4Very high141 Ų14155.8 Ų55.866%0.65927%0.273SS*.THydrogen-bonded Turntrans-73.1-29.6179.8-56.469.4-143.800112K331 I335K331-E333 WeakPolarHBondContact CB-OE2 3.15Å; K331-E333 PolarHBondContact O-N 3.4Å; E333-I335 PolarHBondContact O-N 2.92Å
334D96Very high96.4Very high84 Ų8454.2 Ų54.245%0.44926%0.263SS..THydrogen-bonded Turntrans-70.3-16.5178.7-59.9-50.6000113L330 K331L330-D334 HydrophobicContact CB-CB 4.47Å; L330-D334 HydrophobicContact CD2-CB 4.27Å; K331-D334 WeakPolarHBondContact CB-OD2 3.4Å; K331-D334 PolarHBondContact N-OD2 3.27Å; K331-D334 PolarHBondContact O-N 3.37Å
335I97.9Very high96.5Very high2 Ų254.4 Ų54.41%0.0126%0.264CS..  trans-78.7121.2178.8-64.3166.9000109.7V199 M325 K332 E333 A337 V338 F358 K360V199-I335 HydrophobicContact CG2-CD1 3.76Å; V199-I335 HydrophobicContact CG2-CG1 4.04Å; V199-I335 HydrophobicContact CG2-CG2 3.97Å; M325-I335 HydrophobicContact CE-CD1 3.82Å; M325-I335 HydrophobicContact SD-CD1 3.79Å; K332-I335 PolarHBondContact O-N 3.06Å; E333-I335 PolarHBondContact O-N 2.92Å; I335-A337 VanDerWaalsContact CG2-O 3.28Å; I335-A337 WeakPolarHBondContact CG2-O 3.4Å; I335-V338 HydrophobicContact CG2-CG2 4.04Å; I335-F358 HydrophobicContact CD1-CD1 3.54Å; I335-F358 HydrophobicContact CD1-CE1 3.46Å; I335-F358 VanDerWaalsContact CD1-CE1 3.46Å; I335-K360 HydrophobicContact CG2-CD 4.39Å; I335-K360 WeakPolarHBondContact O-CE 3.49Å; I335-K360 PolarHBondContact O-NZ 3.37Å
336Y97.4Very high96.5Very high131 Ų13158.4 Ų58.451%0.51428%0.278SS..  trans-70.9-50.4173.9177.7-93000111.5R196 I197 V198R196-Y336 HydrophobicContact CG-CD1 3.75Å; R196-Y336 HydrophobicContact CG-CD2 4.04Å; R196-Y336 HydrophobicContact CG-CE1 4.41Å; R196-Y336 HydrophobicContact CG-CG 3.55Å; I197-Y336 VanDerWaalsContact O-CB 3.25Å; I197-Y336 WeakPolarHBondContact O-CB 3.14Å; I197-Y336 PolarHBondContact O-N 3.03Å; V198-Y336 HydrophobicContact CG2-CD1 4.43Å
337A97.3Very high96.5Very high7 Ų751.3 Ų51.36%0.05825%0.245CC..EExtended strand (participates in β ladder)trans-149.2159.5-177.600000112.7V198 V199 I335V198-A337 WeakPolarHBondContact CA-O 3.32Å; V198-A337 HydrophobicContact CG1-CB 4.36Å; V199-A337 PolarHBondContact N-O 2.84Å; I335-A337 VanDerWaalsContact CG2-O 3.28Å; I335-A337 WeakPolarHBondContact CG2-O 3.4Å
338V98.2Very high96.6Very high0 Ų050.5 Ų50.50%024%0.244CC..EExtended strand (participates in β ladder)trans-122.4110171.5-175.30000107.3V199 V201 I335 I354 F358 L362 N363V199-V338 HydrophobicContact CB-CG1 4.42Å; V199-V338 HydrophobicContact CB-CG2 4.41Å; V199-V338 CarbonylContact O-C 3.56Å; V199-V338 WeakPolarHBondContact O-CA 3.46Å; V201-V338 HydrophobicContact CG2-CG1 3.96Å; I335-V338 HydrophobicContact CG2-CG2 4.04Å; V338-I354 HydrophobicContact CG1-CG2 4.04Å; V338-F358 HydrophobicContact CB-CD2 4.33Å; V338-F358 HydrophobicContact CG1-CD2 3.9Å; V338-F358 HydrophobicContact CG1-CE2 3.85Å; V338-F358 HydrophobicContact CG2-CB 4.09Å; V338-F358 HydrophobicContact CG2-CD1 4.24Å; V338-F358 HydrophobicContact CG2-CD2 3.58Å; V338-F358 HydrophobicContact CG2-CE2 4.01Å; V338-F358 HydrophobicContact CG2-CG 3.71Å; V338-L362 HydrophobicContact CB-CD2 4Å; V338-L362 HydrophobicContact CG1-CD2 3.85Å; V338-N363 PolarHBondContact O-N 3.3Å
339E98.1Very high96.7Very high2 Ų249.8 Ų49.81%0.00924%0.241CC..EExtended strand (participates in β ladder)trans-98.1133.3178.3-56.6-80.7155.600109.3Y181 V198 V199 F200 V201 N363 T365Y181-E339 HydrophobicContact CD2-CG 4.16Å; Y181-E339 VanDerWaalsContact CE2-CD 3.47Å; Y181-E339 HydrophobicContact CE2-CG 3.77Å; Y181-E339 WeakPolarHBondContact CE2-OE1 3.35Å; V198-E339 HydrophobicContact CG1-CG 3.85Å; V199-E339 PolarHBondContact O-N 3.03Å; F200-E339 WeakPolarHBondContact CA-O 3.24Å; F200-E339 HydrophobicContact CD1-CB 3.69Å; F200-E339 HydrophobicContact CD1-CG 4.25Å; F200-E339 HydrophobicContact CE1-CB 3.78Å; F200-E339 HydrophobicContact CE1-CG 3.83Å; V201-E339 PolarHBondContact N-O 3.34Å; E339-N363 WeakPolarHBondContact CA-O 3.16Å; E339-N363 HydrophobicContact CG-CB 4.15Å; E339-N363 WeakPolarHBondContact OE1-CB 3.37Å; E339-N363 PolarHBondContact OE1-ND2 3.04Å; E339-N363 VanDerWaalsContact OE2-CB 3.31Å; E339-N363 WeakPolarHBondContact OE2-CB 3.27Å; E339-T365 VanDerWaalsContact CD-OG1 3.24Å; E339-T365 PolarHBondContact OE1-OG1 2.88Å; E339-T365 WeakPolarHBondContact OE2-CB 3.38Å; E339-T365 PolarHBondContact OE2-N 2.82Å; E339-T365 PolarHBondContact OE2-OG1 2.72Å
340I97.9Very high96.8Very high5 Ų541 Ų413%0.02620%0.203CC..EExtended strand (participates in β ladder)trans-108.3137.4179.165.4177.2000112.3V201 T345 K351 L362 N363 T364V201-I340 HydrophobicContact CB-CG2 4.32Å; V201-I340 WeakPolarHBondContact O-CA 3.35Å; I340-T345 HydrophobicContact CB-CG2 4.29Å; I340-K351 HydrophobicContact CD1-CD 4.22Å; I340-K351 HydrophobicContact CD1-CG 4.07Å; I340-L362 HydrophobicContact CD1-CB 4.33Å; I340-L362 HydrophobicContact CD1-CD1 4.3Å; I340-L362 HydrophobicContact CG2-CB 4.27Å; I340-L362 HydrophobicContact CG2-CD1 4.1Å; I340-N363 PolarHBondContact N-O 3.26Å; I340-T364 HydrophobicContact CD1-CG2 4.02Å; I340-T364 HydrophobicContact CG1-CG2 3.65Å
341V97.3Very high96.8Very high1 Ų142.8 Ų42.81%0.00621%0.209CC..EExtended strand (participates in β ladder)trans-140175.7178.7-62.50000110.6V177 V201 D202 L203 T345 L366 A371V177-V341 HydrophobicContact CG1-CG1 3.8Å; V177-V341 HydrophobicContact CG1-CG2 4.11Å; V177-V341 HydrophobicContact CG2-CG2 4.16Å; V201-V341 PolarHBondContact O-N 3.06Å; D202-V341 WeakPolarHBondContact CA-O 3.46Å; D202-V341 HydrophobicContact CB-CG2 3.66Å; L203-V341 PolarHBondContact N-O 3Å; V341-T345 WeakPolarHBondContact O-CG2 3.2Å; V341-T345 PolarHBondContact O-OG1 2.95Å; V341-L366 HydrophobicContact CG1-CB 4.45Å; V341-L366 HydrophobicContact CG1-CD1 4.38Å; V341-A371 HydrophobicContact CG1-CB 4.43Å
342G95.4Very high96.9Very high8 Ų841.8 Ų41.88%0.08221%0.206CC..SBendtrans79.6138.5-178.900000112.8D202 L203 A344 T345 A368D202-G342 VanDerWaalsContact OD1-CA 3.31Å; D202-G342 WeakPolarHBondContact OD1-CA 3.41Å; L203-G342 CarbonylContact O-C 3.54Å; G342-A344 VanDerWaalsContact C-N 3.27Å; G342-A344 PolarHBondContact O-N 3Å; G342-A344 VanDerWaalsContact O-N 3.09Å; G342-T345 PolarHBondContact O-N 3.3Å; G342-T345 PolarHBondContact O-OG1 2.93Å; G342-A368 PolarHBondContact N-O 3.16Å
343G94.6Very high97Very high37 Ų3741.4 Ų41.438%0.38120%0.203SC..G310 helixtrans-62.6-24.4-162.800000116.5L203 R346L203-G343 PolarHBondContact O-N 2.99Å; G343-R346 WeakPolarHBondContact O-CB 3.31Å; G343-R346 WeakPolarHBondContact O-CG 3.49Å
344A96.7Very high97.1Very high7 Ų734.7 Ų34.76%0.05817%0.171CC..G310 helixtrans-91.6-9.6-177.700000114.1L203 G342 R346 I347L203-A344 HydrophobicContact CB-CB 4.47Å; L203-A344 HydrophobicContact CD2-CB 3.88Å; L203-A344 HydrophobicContact CG-CB 3.84Å; L203-A344 WeakPolarHBondContact O-CB 3.31Å; L203-A344 PolarHBondContact O-N 3.08Å; G342-A344 VanDerWaalsContact C-N 3.27Å; G342-A344 PolarHBondContact O-N 3Å; G342-A344 VanDerWaalsContact O-N 3.09Å; A344-R346 PolarHBondContact O-N 3.36Å; A344-R346 VanDerWaalsContact O-N 3.08Å; A344-I347 HydrophobicContact CB-CD1 4.43Å; A344-I347 WeakPolarHBondContact O-CG1 3.21Å; A344-I347 PolarHBondContact O-N 3.08Å; A344-I347 VanDerWaalsContact O-N 3.16Å
345T97.2Very high97.2Very high3 Ų333 Ų332%0.01817%0.165CC..G310 helixtrans-64.1-9.1165.561.30000112.9L203 I340 V341 G342 I347 K351L203-T345 HydrophobicContact CB-CG2 3.61Å; I340-T345 HydrophobicContact CB-CG2 4.29Å; V341-T345 WeakPolarHBondContact O-CG2 3.2Å; V341-T345 PolarHBondContact O-OG1 2.95Å; G342-T345 PolarHBondContact O-N 3.3Å; G342-T345 PolarHBondContact O-OG1 2.93Å; T345-I347 VanDerWaalsContact C-N 3.27Å; T345-I347 PolarHBondContact O-N 2.84Å; T345-K351 WeakPolarHBondContact O-CE 3.23Å; T345-K351 WeakPolarHBondContact O-CG 3.15Å
346R96.8Very high97.1Very high106 Ų10640.5 Ų40.540%0.420%0.198SC..G310 helixtrans-68.8-20.6172.7-65.8-178.8168.1111.9-3.9113.6G343 A344 D369G343-R346 WeakPolarHBondContact O-CB 3.31Å; G343-R346 WeakPolarHBondContact O-CG 3.49Å; A344-R346 PolarHBondContact O-N 3.36Å; A344-R346 VanDerWaalsContact O-N 3.08Å; R346-D369 IonicContact CZ-OD1 2.71Å; R346-D369 IonicContact CZ-OD2 2.69Å; R346-D369 IonicContact NH1-OD1 2.61Å; R346-D369 PolarHBondContact NH1-OD1 3.1Å; R346-D369 IonicContact NH1-OD2 2.61Å; R346-D369 PolarHBondContact NH1-OD2 2.75Å; R346-D369 VanDerWaalsContact NH1-OD2 3.15Å; R346-D369 IonicContact NH2-OD1 2.64Å; R346-D369 IonicContact NH2-OD2 3.73Å; R346-D369 PolarHBondContact NH2-OD2 2.85Å
347I97.4Very high97.1Very high4 Ų434.9 Ų34.92%0.02118%0.176CC..SBendtrans-65.5126.2178.1-62.7170.9000109.9F236 K274 F306 A344 T345 A349 I350 K351F236-I347 HydrophobicContact CD1-CD1 4.15Å; F236-I347 HydrophobicContact CD2-CD1 4.27Å; F236-I347 HydrophobicContact CE1-CD1 4.4Å; F236-I347 HydrophobicContact CG-CD1 4.1Å; K274-I347 HydrophobicContact CD-CD1 4.41Å; F306-I347 HydrophobicContact CE1-CG2 4.48Å; A344-I347 HydrophobicContact CB-CD1 4.43Å; A344-I347 WeakPolarHBondContact O-CG1 3.21Å; A344-I347 PolarHBondContact O-N 3.08Å; A344-I347 VanDerWaalsContact O-N 3.16Å; T345-I347 VanDerWaalsContact C-N 3.27Å; T345-I347 PolarHBondContact O-N 2.84Å; I347-A349 PolarHBondContact O-N 3.34Å; I347-I350 HydrophobicContact CB-CB 4.37Å; I347-I350 HydrophobicContact CB-CG1 3.8Å; I347-I350 HydrophobicContact CG2-CG1 4.03Å; I347-I350 WeakPolarHBondContact O-CB 3.2Å; I347-I350 PolarHBondContact O-N 2.69Å; I347-I350 VanDerWaalsContact O-N 3.09Å; I347-K351 PolarHBondContact O-N 2.92Å
348P97.1Very high97.1Very high35 Ų3534.8 Ų34.823%0.22717%0.174CC..Hα-helixtrans-55.6-49.4-175.6-30.738.5000114.9I350 K351 E352P348-I350 PolarHBondContact O-N 2.65Å; P348-I350 VanDerWaalsContact O-N 3.15Å; P348-K351 PolarHBondContact O-N 3.35Å; P348-E352 PolarHBondContact O-N 2.78Å
349A97.3Very high97Very high13 Ų1338 Ų3811%0.10721%0.208CC..Hα-helixtrans-60.7-22.2177.400000115E307 L314 I347 R353E307-A349 HydrophobicContact CG-CB 3.95Å; E307-A349 WeakPolarHBondContact OE1-CB 3.17Å; E307-A349 PolarHBondContact OE1-N 3.16Å; E307-A349 VanDerWaalsContact OE1-N 3.1Å; L314-A349 HydrophobicContact CD1-CB 3.87Å; L314-A349 HydrophobicContact CD2-CB 3.86Å; I347-A349 PolarHBondContact O-N 3.34Å; A349-R353 PolarHBondContact O-N 2.8Å
350I97.7Very high96.8Very high0 Ų040.9 Ų40.90%022%0.221CC..Hα-helixtrans-71.4-48.6172.3-60.5-64.9000110L203 F236 L314 V317 I347 P348 R353 I354L203-I350 HydrophobicContact CD2-CD1 3.93Å; L203-I350 HydrophobicContact CD2-CG1 4.02Å; L203-I350 HydrophobicContact CD2-CG2 3.99Å; F236-I350 HydrophobicContact CZ-CD1 4Å; L314-I350 HydrophobicContact CD2-CD1 3.63Å; L314-I350 HydrophobicContact CD2-CG1 4.3Å; V317-I350 HydrophobicContact CG2-CD1 3.58Å; I347-I350 HydrophobicContact CB-CB 4.37Å; I347-I350 HydrophobicContact CB-CG1 3.8Å; I347-I350 HydrophobicContact CG2-CG1 4.03Å; I347-I350 WeakPolarHBondContact O-CB 3.2Å; I347-I350 PolarHBondContact O-N 2.69Å; I347-I350 VanDerWaalsContact O-N 3.09Å; P348-I350 PolarHBondContact O-N 2.65Å; P348-I350 VanDerWaalsContact O-N 3.15Å; I350-R353 PolarHBondContact O-N 2.87Å; I350-I354 HydrophobicContact CG2-CD1 3.62Å; I350-I354 HydrophobicContact CG2-CG1 4.48Å; I350-I354 WeakPolarHBondContact O-CD1 3.43Å; I350-I354 WeakPolarHBondContact O-CG1 3.3Å; I350-I354 PolarHBondContact O-N 3.07Å; I350-I354 VanDerWaalsContact O-N 3.11Å
351K96.9Very high96.7Very high86 Ų8648.6 Ų48.637%0.37426%0.257SS..Hα-helixtrans-60.2-49.4175.7-60.1-175.1-178.2-179.10111I340 T345 I347 P348 R353 I354 C355 L362I340-K351 HydrophobicContact CD1-CD 4.22Å; I340-K351 HydrophobicContact CD1-CG 4.07Å; T345-K351 WeakPolarHBondContact O-CE 3.23Å; T345-K351 WeakPolarHBondContact O-CG 3.15Å; I347-K351 PolarHBondContact O-N 2.92Å; P348-K351 PolarHBondContact O-N 3.35Å; K351-R353 PolarHBondContact O-N 2.99Å; K351-I354 PolarHBondContact O-N 3.25Å; K351-C355 WeakPolarHBondContact O-CB 3.37Å; K351-C355 PolarHBondContact O-N 3.37Å; K351-L362 HydrophobicContact CB-CD1 4.02Å; K351-L362 HydrophobicContact CG-CD1 4.47Å; K351-L362 WeakPolarHBondContact O-CD1 3.5Å
352E96.9Very high96.7Very high124 Ų12449.8 Ų49.858%0.57926%0.263SS*.Hα-helixtrans-9-86.7148179.4-137.5-160.600114.1P348 C355 K356P348-E352 PolarHBondContact O-N 2.78Å; E352-C355 PolarHBondContact O-N 2.95Å; E352-K356 VanDerWaalsContact O-CB 3.3Å; E352-K356 WeakPolarHBondContact O-CB 3.33Å; E352-K356 PolarHBondContact O-N 2.85Å
353R97.3Very high96.8Very high74 Ų7452 Ų5228%0.27927%0.273SS..Hα-helixtrans-68.3-37.3-169.4-69.3174.4177.6-967.7113.4L314 V317 E318 A349 I350 K351 F357L314-R353 WeakPolarHBondContact O-CD 3.47Å; L314-R353 PolarHBondContact O-NE 3.36Å; V317-R353 HydrophobicContact CG1-CB 4.35Å; E318-R353 IonicContact OE1-CZ 3.17Å; E318-R353 IonicContact OE1-NH1 3.86Å; E318-R353 PolarHBondContact OE1-NH1 3.13Å; A349-R353 PolarHBondContact O-N 2.8Å; I350-R353 PolarHBondContact O-N 2.87Å; K351-R353 PolarHBondContact O-N 2.99Å; R353-F357 WeakPolarHBondContact O-CB 3.45Å; R353-F357 PolarHBondContact O-N 2.94Å
354I97.7Very high96.9Very high0 Ų054.8 Ų54.80%028%0.283CS..Hα-helixtrans-66.7-44.9179.2-56.6160.2000110V201 V317 L321 V338 I350 K351 F357 F358 L362V201-I354 HydrophobicContact CG1-CD1 3.8Å; V201-I354 HydrophobicContact CG1-CG1 4.46Å; V201-I354 HydrophobicContact CG2-CG2 4.19Å; V317-I354 HydrophobicContact CG1-CG1 4.12Å; L321-I354 HydrophobicContact CD1-CG1 4.27Å; V338-I354 HydrophobicContact CG1-CG2 4.04Å; I350-I354 HydrophobicContact CG2-CD1 3.62Å; I350-I354 HydrophobicContact CG2-CG1 4.48Å; I350-I354 WeakPolarHBondContact O-CD1 3.43Å; I350-I354 WeakPolarHBondContact O-CG1 3.3Å; I350-I354 PolarHBondContact O-N 3.07Å; I350-I354 VanDerWaalsContact O-N 3.11Å; K351-I354 PolarHBondContact O-N 3.25Å; I354-F357 PolarHBondContact O-N 2.86Å; I354-F358 HydrophobicContact CG2-CD2 3.86Å; I354-F358 HydrophobicContact CG2-CE2 3.9Å; I354-F358 WeakPolarHBondContact O-CD2 3.45Å; I354-F358 PolarHBondContact O-N 3.33Å; I354-F358 VanDerWaalsContact O-N 3.08Å; I354-L362 HydrophobicContact CB-CD1 3.97Å; I354-L362 HydrophobicContact CB-CD2 4.26Å; I354-L362 HydrophobicContact CG2-CD1 4.19Å; I354-L362 HydrophobicContact CG2-CD2 3.7Å
355C97.1Very high96.7Very high48 Ų4858 Ų5832%0.32430%0.301SS..Hα-helixtrans-59.8-51175.6-179.90000111.1K351 E352 F357 F358 G359 K360 L362K351-C355 WeakPolarHBondContact O-CB 3.37Å; K351-C355 PolarHBondContact O-N 3.37Å; E352-C355 PolarHBondContact O-N 2.95Å; C355-F357 VanDerWaalsContact C-N 3.33Å; C355-F357 PolarHBondContact O-N 2.97Å; C355-F358 PolarHBondContact O-N 2.68Å; C355-G359 WeakPolarHBondContact O-CA 3.02Å; C355-G359 PolarHBondContact O-N 2.87Å; C355-K360 PolarHBondContact O-N 3.32Å; C355-K360 PolarHBondContact SG-O 2.82Å; C355-K360 VanDerWaalsContact SG-O 3.34Å; C355-L362 HydrophobicContact CB-CD1 4.18Å; C355-L362 HydrophobicContact CB-CD2 4.37Å; C355-L362 HydrophobicContact CB-CG 4.04Å
356K97.1Very high96.6Very high160 Ų16059.2 Ų59.270%0.69631%0.307SS*.Hα-helixtrans-62-36.2177.9-173.9176.4-176.6173.30113.1E352E352-K356 VanDerWaalsContact O-CB 3.3Å; E352-K356 WeakPolarHBondContact O-CB 3.33Å; E352-K356 PolarHBondContact O-N 2.85Å
357F97.3Very high96.5Very high12 Ų1257.5 Ų57.55%0.05331%0.307CS..Hα-helixtrans-65.8-49.5176.4177.3-87.9000111.1L321 H322 M325 K332 R353 I354 C355L321-F357 HydrophobicContact CB-CD1 3.85Å; L321-F357 HydrophobicContact CB-CD2 4.13Å; L321-F357 HydrophobicContact CB-CE1 3.68Å; L321-F357 HydrophobicContact CB-CE2 3.95Å; L321-F357 HydrophobicContact CB-CG 4.09Å; L321-F357 HydrophobicContact CB-CZ 3.73Å; L321-F357 HydrophobicContact CD1-CB 3.96Å; L321-F357 HydrophobicContact CD1-CD1 3.99Å; L321-F357 HydrophobicContact CD1-CD2 4.38Å; L321-F357 HydrophobicContact CD1-CG 3.84Å; L321-F357 HydrophobicContact CG-CD1 4.45Å; H322-F357 AromaticContact CD2-CE2 3.69Å; H322-F357 AromaticContact CE1-CE2 3.88Å; H322-F357 AromaticContact CG-CE2 3.85Å; H322-F357 AromaticContact ND1-CE2 3.97Å; H322-F357 AromaticContact NE2-CE2 3.7Å; M325-F357 HydrophobicContact CG-CE1 4.04Å; M325-F357 HydrophobicContact CG-CZ 4.07Å; K332-F357 WeakPolarHBondContact CD-O 3.48Å; K332-F357 WeakPolarHBondContact CE-O 3.45Å; K332-F357 PolarHBondContact NZ-O 3.19Å; R353-F357 WeakPolarHBondContact O-CB 3.45Å; R353-F357 PolarHBondContact O-N 2.94Å; I354-F357 PolarHBondContact O-N 2.86Å; C355-F357 VanDerWaalsContact C-N 3.33Å; C355-F357 PolarHBondContact O-N 2.97Å
358F96.9Very high96.2Very high5 Ų558.3 Ų58.32%0.02231%0.314CS..Hα-helixtrans-81.9-19.4-177.4-71.8-66.4000114.4V199 L321 M325 I335 V338 I354 C355 K360V199-F358 HydrophobicContact CB-CZ 4.4Å; V199-F358 HydrophobicContact CG1-CZ 4Å; V199-F358 HydrophobicContact CG2-CE1 4.29Å; V199-F358 HydrophobicContact CG2-CZ 4.27Å; L321-F358 HydrophobicContact CD2-CE2 3.79Å; L321-F358 HydrophobicContact CD2-CZ 3.93Å; M325-F358 HydrophobicContact SD-CE1 4.07Å; I335-F358 HydrophobicContact CD1-CD1 3.54Å; I335-F358 HydrophobicContact CD1-CE1 3.46Å; I335-F358 VanDerWaalsContact CD1-CE1 3.46Å; V338-F358 HydrophobicContact CB-CD2 4.33Å; V338-F358 HydrophobicContact CG1-CD2 3.9Å; V338-F358 HydrophobicContact CG1-CE2 3.85Å; V338-F358 HydrophobicContact CG2-CB 4.09Å; V338-F358 HydrophobicContact CG2-CD1 4.24Å; V338-F358 HydrophobicContact CG2-CD2 3.58Å; V338-F358 HydrophobicContact CG2-CE2 4.01Å; V338-F358 HydrophobicContact CG2-CG 3.71Å; I354-F358 HydrophobicContact CG2-CD2 3.86Å; I354-F358 HydrophobicContact CG2-CE2 3.9Å; I354-F358 WeakPolarHBondContact O-CD2 3.45Å; I354-F358 PolarHBondContact O-N 3.33Å; I354-F358 VanDerWaalsContact O-N 3.08Å; C355-F358 PolarHBondContact O-N 2.68Å; F358-K360 VanDerWaalsContact C-N 3.25Å; F358-K360 HydrophobicContact CB-CB 4.3Å
359G96.2Very high96.1Very high69 Ų6958.7 Ų58.771%0.71131%0.314SS*.THydrogen-bonded Turntrans67.627.7-17200000112.6C355C355-G359 WeakPolarHBondContact O-CA 3.02Å; C355-G359 PolarHBondContact O-N 2.87Å
360K95Very high96Very high62 Ų6258.8 Ų58.827%0.2731%0.312SS..SBendtrans-140.6145.2-172.4-69.9172.5-175.5-88.20109.8K332 I335 C355 F358K332-K360 WeakPolarHBondContact O-CE 3.45Å; I335-K360 HydrophobicContact CG2-CD 4.39Å; I335-K360 WeakPolarHBondContact O-CE 3.49Å; I335-K360 PolarHBondContact O-NZ 3.37Å; C355-K360 PolarHBondContact O-N 3.32Å; C355-K360 PolarHBondContact SG-O 2.82Å; C355-K360 VanDerWaalsContact SG-O 3.34Å; F358-K360 VanDerWaalsContact C-N 3.25Å; F358-K360 HydrophobicContact CB-CB 4.3Å
361E95.7Very high96Very high167 Ų16758.9 Ų58.978%0.7831%0.313SS*.PPolyproline II helixtrans-61.1151169.6-172.1168.4-164.100111.1
362L97.3Very high96Very high26 Ų2655.3 Ų55.314%0.13630%0.298CS..PPolyproline II helixtrans-99.3122.6-176-55.2-178.1000110.6V338 I340 K351 I354 C355V338-L362 HydrophobicContact CB-CD2 4Å; V338-L362 HydrophobicContact CG1-CD2 3.85Å; I340-L362 HydrophobicContact CD1-CB 4.33Å; I340-L362 HydrophobicContact CD1-CD1 4.3Å; I340-L362 HydrophobicContact CG2-CB 4.27Å; I340-L362 HydrophobicContact CG2-CD1 4.1Å; K351-L362 HydrophobicContact CB-CD1 4.02Å; K351-L362 HydrophobicContact CG-CD1 4.47Å; K351-L362 WeakPolarHBondContact O-CD1 3.5Å; I354-L362 HydrophobicContact CB-CD1 3.97Å; I354-L362 HydrophobicContact CB-CD2 4.26Å; I354-L362 HydrophobicContact CG2-CD1 4.19Å; I354-L362 HydrophobicContact CG2-CD2 3.7Å; C355-L362 HydrophobicContact CB-CD1 4.18Å; C355-L362 HydrophobicContact CB-CD2 4.37Å; C355-L362 HydrophobicContact CB-CG 4.04Å
363N96.9Very high96.1Very high54 Ų5449.4 Ų49.429%0.28927%0.271SS..BIsolated β-bridgetrans-78.3145.6177.7-73.98.8000111.5V338 E339 I340 T365V338-N363 PolarHBondContact O-N 3.3Å; E339-N363 WeakPolarHBondContact CA-O 3.16Å; E339-N363 HydrophobicContact CG-CB 4.15Å; E339-N363 WeakPolarHBondContact OE1-CB 3.37Å; E339-N363 PolarHBondContact OE1-ND2 3.04Å; E339-N363 VanDerWaalsContact OE2-CB 3.31Å; E339-N363 WeakPolarHBondContact OE2-CB 3.27Å; I340-N363 PolarHBondContact N-O 3.26Å; N363-T365 HydrophobicContact CB-CG2 4.33Å
364T95.6Very high96.1Very high96 Ų9648.9 Ų48.959%0.58927%0.269SS*.  trans-128.648.1169.649.10000110I340 L366I340-T364 HydrophobicContact CD1-CG2 4.02Å; I340-T364 HydrophobicContact CG1-CG2 3.65Å; T364-L366 PolarHBondContact O-N 2.75Å
365T93.8Very high96Very high73 Ų7348.9 Ų48.945%0.44827%0.269SS..  trans-75.5-8.8-177.3700000113.4Y181 E339 N363Y181-T365 WeakPolarHBondContact CE2-OG1 3.5Å; E339-T365 VanDerWaalsContact CD-OG1 3.24Å; E339-T365 PolarHBondContact OE1-OG1 2.88Å; E339-T365 WeakPolarHBondContact OE2-CB 3.38Å; E339-T365 PolarHBondContact OE2-N 2.82Å; E339-T365 PolarHBondContact OE2-OG1 2.72Å; N363-T365 HydrophobicContact CB-CG2 4.33Å
366L93.8Very high96.1Very high29 Ų2946.6 Ų46.615%0.15225%0.253CS..SBendtrans-108149.8173.2-58178.5000110.5V177 Y181 F200 V341 T364 A368 A371V177-L366 HydrophobicContact CG1-CD1 3.49Å; V177-L366 VanDerWaalsContact CG1-CD1 3.49Å; Y181-L366 HydrophobicContact CD2-CD1 4.48Å; Y181-L366 HydrophobicContact CD2-CD2 4.36Å; Y181-L366 HydrophobicContact CD2-CG 4.38Å; F200-L366 HydrophobicContact CE1-CD1 4.13Å; V341-L366 HydrophobicContact CG1-CB 4.45Å; V341-L366 HydrophobicContact CG1-CD1 4.38Å; T364-L366 PolarHBondContact O-N 2.75Å; L366-A368 PolarHBondContact O-N 2.82Å; L366-A368 VanDerWaalsContact O-N 3.17Å; L366-A371 HydrophobicContact CB-CB 4.15Å; L366-A371 HydrophobicContact CD1-CB 4.2Å
367N94.8Very high96.1Very high71 Ų7139 Ų3938%0.3822%0.22SC..  trans-68.1112.8164.1178.5-28.9000108.8D369 E370 A371N367-D369 PolarHBondContact O-N 2.86Å; N367-D369 VanDerWaalsContact O-N 3.11Å; N367-D369 PolarHBondContact OD1-N 2.81Å; N367-E370 HydrophobicContact CB-CB 4.06Å; N367-E370 HydrophobicContact CB-CG 4.41Å; N367-E370 VanDerWaalsContact ND2-CG 3.32Å; N367-E370 WeakPolarHBondContact ND2-CG 3.44Å; N367-E370 PolarHBondContact ND2-OE1 3.33Å; N367-E370 PolarHBondContact O-N 2.87Å; N367-E370 PolarHBondContact OD1-N 3.01Å; N367-A371 VanDerWaalsContact O-CB 3.3Å; N367-A371 WeakPolarHBondContact O-CB 3.38Å; N367-A371 PolarHBondContact O-N 2.8Å
368A92.9Very high96Very high21 Ų2138.9 Ų38.917%0.17422%0.22CC..THydrogen-bonded Turntrans-60.3-19.2-173.100000115.4G342 L366G342-A368 PolarHBondContact N-O 3.16Å; L366-A368 PolarHBondContact O-N 2.82Å; L366-A368 VanDerWaalsContact O-N 3.17Å
369D94.1Very high96Very high43 Ų4338.9 Ų38.923%0.2322%0.22CC..THydrogen-bonded Turntrans-101.8-34.5176.8-52.6-54.3000112.3Y14 R346 N367Y14-D369 WeakPolarHBondContact CD2-O 3.24Å; Y14-D369 HydrophobicContact CE1-CB 4.22Å; Y14-D369 HydrophobicContact CE2-CB 4.11Å; R346-D369 IonicContact CZ-OD1 2.71Å; R346-D369 IonicContact CZ-OD2 2.69Å; R346-D369 IonicContact NH1-OD1 2.61Å; R346-D369 PolarHBondContact NH1-OD1 3.1Å; R346-D369 IonicContact NH1-OD2 2.61Å; R346-D369 PolarHBondContact NH1-OD2 2.75Å; R346-D369 VanDerWaalsContact NH1-OD2 3.15Å; R346-D369 IonicContact NH2-OD1 2.64Å; R346-D369 IonicContact NH2-OD2 3.73Å; R346-D369 PolarHBondContact NH2-OD2 2.85Å; N367-D369 PolarHBondContact O-N 2.86Å; N367-D369 VanDerWaalsContact O-N 3.11Å; N367-D369 PolarHBondContact OD1-N 2.81Å
370E95.9Very high96Very high15 Ų1535.6 Ų35.67%0.0719%0.186CC..THydrogen-bonded Turntrans-87.4-18.1-175.6-63.9-178.6-16900114.6T25 R33 N367 V372 A373 R374T25-E370 HydrophobicContact CG2-CB 3.74Å; T25-E370 HydrophobicContact CG2-CG 3.71Å; T25-E370 PolarHBondContact OG1-OE1 3.26Å; T25-E370 PolarHBondContact OG1-OE2 2.92Å; R33-E370 WeakPolarHBondContact CD-OE1 3.33Å; R33-E370 IonicContact CZ-OE1 2.66Å; R33-E370 IonicContact NE-OE1 3.59Å; R33-E370 IonicContact NH1-OE1 2.99Å; R33-E370 PolarHBondContact NH1-OE1 3.05Å; R33-E370 IonicContact NH1-OE2 3.19Å; N367-E370 HydrophobicContact CB-CB 4.06Å; N367-E370 HydrophobicContact CB-CG 4.41Å; N367-E370 VanDerWaalsContact ND2-CG 3.32Å; N367-E370 WeakPolarHBondContact ND2-CG 3.44Å; N367-E370 PolarHBondContact ND2-OE1 3.33Å; N367-E370 PolarHBondContact O-N 2.87Å; N367-E370 PolarHBondContact OD1-N 3.01Å; E370-V372 VanDerWaalsContact C-N 3.35Å; E370-V372 PolarHBondContact O-N 2.97Å; E370-A373 PolarHBondContact O-N 2.76Å; E370-R374 HydrophobicContact CB-CG 4.42Å; E370-R374 WeakPolarHBondContact O-CB 3.11Å; E370-R374 WeakPolarHBondContact O-CG 3.31Å; E370-R374 PolarHBondContact O-N 2.89Å; E370-R374 IonicContact OE2-CZ 2.78Å; E370-R374 VanDerWaalsContact OE2-CZ 3.25Å; E370-R374 IonicContact OE2-NE 3.72Å; E370-R374 PolarHBondContact OE2-NE 2.64Å; E370-R374 IonicContact OE2-NH2 3.42Å; E370-R374 PolarHBondContact OE2-NH2 2.8Å
371A96.2Very high96Very high2 Ų232.8 Ų32.82%0.01717%0.174CC..Hα-helixtrans-59.3-39.5-16800000114V177 V341 L366 N367 G375V177-A371 HydrophobicContact CG1-CB 4.34Å; V177-A371 HydrophobicContact CG2-CB 3.99Å; V341-A371 HydrophobicContact CG1-CB 4.43Å; L366-A371 HydrophobicContact CB-CB 4.15Å; L366-A371 HydrophobicContact CD1-CB 4.2Å; N367-A371 VanDerWaalsContact O-CB 3.3Å; N367-A371 WeakPolarHBondContact O-CB 3.38Å; N367-A371 PolarHBondContact O-N 2.8Å; A371-G375 PolarHBondContact O-N 3.3Å
372V97.8Very high95.9Very high11 Ų1127.4 Ų27.47%0.06715%0.15CC..Hα-helixtrans-65-50.8179.8-177.80000110.8D7 E173 A176 V177 E370 R374 G375 C376D7-V372 HydrophobicContact CB-CB 3.99Å; D7-V372 HydrophobicContact CB-CG1 3.89Å; D7-V372 VanDerWaalsContact OD1-CG1 3.23Å; D7-V372 WeakPolarHBondContact OD1-CG1 3.44Å; E173-V372 HydrophobicContact CB-CG1 4.32Å; E173-V372 HydrophobicContact CB-CG2 4.45Å; E173-V372 HydrophobicContact CG-CG1 4.11Å; A176-V372 HydrophobicContact CB-CG1 4.18Å; A176-V372 WeakPolarHBondContact CB-O 3.39Å; V177-V372 HydrophobicContact CG2-CB 4.47Å; V177-V372 HydrophobicContact CG2-CG2 3.59Å; E370-V372 VanDerWaalsContact C-N 3.35Å; E370-V372 PolarHBondContact O-N 2.97Å; V372-R374 PolarHBondContact O-N 3.48Å; V372-G375 PolarHBondContact O-N 2.69Å; V372-C376 PolarHBondContact O-N 3.17Å; V372-C376 PolarHBondContact O-SG 3.12Å
373A98.2Very high95.7Very high0 Ų029.8 Ų29.80%016%0.163CC..Hα-helixtrans-62.9-43.9-179.700000111.4D7 Y14 A16 E370 G375 C376 A377D7-A373 HydrophobicContact CB-CB 3.82Å; Y14-A373 WeakPolarHBondContact O-CB 3.34Å; A16-A373 HydrophobicContact CB-CB 3.95Å; A16-A373 WeakPolarHBondContact CB-O 3.3Å; E370-A373 PolarHBondContact O-N 2.76Å; A373-G375 VanDerWaalsContact C-N 3.31Å; A373-G375 PolarHBondContact O-N 2.72Å; A373-C376 PolarHBondContact O-N 2.61Å; A373-A377 PolarHBondContact O-N 3.47Å
374R97.2Very high95.4Very high62 Ų6227.6 Ų27.623%0.23415%0.152CC..Hα-helixtrans-57.5-43.6173.9-72.6172171.5-84.5-2.5111.6I23 T25 E370 V372 A377 L378I23-R374 HydrophobicContact CG2-CB 4.36Å; I23-R374 HydrophobicContact CG2-CG 4.38Å; I23-R374 PolarHBondContact O-NH1 3.27Å; T25-R374 HydrophobicContact CG2-CG 4.13Å; E370-R374 HydrophobicContact CB-CG 4.42Å; E370-R374 WeakPolarHBondContact O-CB 3.11Å; E370-R374 WeakPolarHBondContact O-CG 3.31Å; E370-R374 PolarHBondContact O-N 2.89Å; E370-R374 IonicContact OE2-CZ 2.78Å; E370-R374 VanDerWaalsContact OE2-CZ 3.25Å; E370-R374 IonicContact OE2-NE 3.72Å; E370-R374 PolarHBondContact OE2-NE 2.64Å; E370-R374 IonicContact OE2-NH2 3.42Å; E370-R374 PolarHBondContact OE2-NH2 2.8Å; V372-R374 PolarHBondContact O-N 3.48Å; R374-A377 PolarHBondContact O-N 3.39Å; R374-L378 WeakPolarHBondContact O-CB 3.4Å; R374-L378 VanDerWaalsContact O-CG 3.29Å; R374-L378 WeakPolarHBondContact O-CG 3.32Å; R374-L378 PolarHBondContact O-N 3.18Å
375G97.2Very high95Very high0 Ų028.9 Ų28.90%016%0.162CC..Hα-helixtrans-60.5-45.3173.800000113.3A176 A371 V372 A373 A377 L378 Q379A176-G375 VanDerWaalsContact O-CA 3.25Å; A176-G375 WeakPolarHBondContact O-CA 3.48Å; A371-G375 PolarHBondContact O-N 3.3Å; V372-G375 PolarHBondContact O-N 2.69Å; A373-G375 VanDerWaalsContact C-N 3.31Å; A373-G375 PolarHBondContact O-N 2.72Å; G375-A377 VanDerWaalsContact C-N 3.34Å; G375-A377 PolarHBondContact O-N 3.26Å; G375-L378 PolarHBondContact O-N 3.22Å; G375-Q379 WeakPolarHBondContact O-CB 3.47Å; G375-Q379 PolarHBondContact O-N 3.04Å
376C98.3Very high94.6Very high0 Ų028.8 Ų28.80%017%0.169CC..Hα-helixtrans-61.9-41.8175.6-65.10000111.6V141 V372 A373 Q379 C380V141-C376 HydrophobicContact CB-CB 4.18Å; V141-C376 WeakPolarHBondContact CB-O 3.44Å; V141-C376 HydrophobicContact CG1-CB 3.82Å; V372-C376 PolarHBondContact O-N 3.17Å; V372-C376 PolarHBondContact O-SG 3.12Å; A373-C376 PolarHBondContact O-N 2.61Å; C376-Q379 PolarHBondContact O-N 3.17Å; C376-C380 WeakPolarHBondContact O-CB 3.45Å; C376-C380 PolarHBondContact O-N 3.25Å
377A97.2Very high94.1Very high0 Ų031.4 Ų31.40%018%0.179CC..Hα-helixtrans-69.4-37.1178.600000112.4V3 A16 I23 A373 R374 G375 C380 A381V3-A377 VanDerWaalsContact CG1-O 3.31Å; V3-A377 WeakPolarHBondContact CG1-O 3.43Å; A16-A377 HydrophobicContact CB-CB 3.69Å; I23-A377 HydrophobicContact CD1-CB 4.28Å; I23-A377 HydrophobicContact CG2-CB 3.64Å; A373-A377 PolarHBondContact O-N 3.47Å; R374-A377 PolarHBondContact O-N 3.39Å; G375-A377 VanDerWaalsContact C-N 3.34Å; G375-A377 PolarHBondContact O-N 3.26Å; A377-C380 PolarHBondContact O-N 3.34Å; A377-A381 PolarHBondContact O-N 3.15Å
378L95.8Very high93.4Very high10 Ų1038.5 Ų38.55%0.05221%0.206CC..Hα-helixtrans-60-44.9169.1-74.9164.6000111.5I23 L179 A180 I183 Y184 R374 G375 C380 A381 I382I23-L378 HydrophobicContact CG1-CD2 3.67Å; I23-L378 HydrophobicContact CG1-CG 3.96Å; L179-L378 HydrophobicContact CD2-CB 3.76Å; L179-L378 HydrophobicContact CG-CB 4.13Å; L179-L378 HydrophobicContact CG-CD1 4.39Å; A180-L378 HydrophobicContact CB-CD1 4.29Å; I183-L378 HydrophobicContact CD1-CD2 4.38Å; I183-L378 HydrophobicContact CG2-CD1 3.75Å; I183-L378 HydrophobicContact CG2-CD2 4.06Å; Y184-L378 HydrophobicContact CE2-CD1 4.08Å; R374-L378 WeakPolarHBondContact O-CB 3.4Å; R374-L378 VanDerWaalsContact O-CG 3.29Å; R374-L378 WeakPolarHBondContact O-CG 3.32Å; R374-L378 PolarHBondContact O-N 3.18Å; G375-L378 PolarHBondContact O-N 3.22Å; L378-C380 VanDerWaalsContact C-N 3.33Å; L378-C380 PolarHBondContact O-N 3.47Å; L378-A381 WeakPolarHBondContact O-CB 3.18Å; L378-A381 PolarHBondContact O-N 2.84Å; L378-I382 WeakPolarHBondContact O-CG1 3.45Å; L378-I382 PolarHBondContact O-N 3.37Å
379Q96.5Very high93.1Very high6 Ų640.4 Ų40.43%0.02822%0.216CC..Hα-helixtrans-65.4-36.1176.4178.461.594.600112.3V141 M171 L179 G375 C376 A381 I382 L383V141-Q379 HydrophobicContact CG1-CB 4.23Å; V141-Q379 HydrophobicContact CG1-CG 4.1Å; V141-Q379 HydrophobicContact CG2-CB 4.42Å; V141-Q379 HydrophobicContact CG2-CG 4.11Å; M171-Q379 HydrophobicContact CE-CB 4Å; M171-Q379 HydrophobicContact CE-CG 4.2Å; M171-Q379 HydrophobicContact SD-CB 3.56Å; M171-Q379 VanDerWaalsContact SD-CB 3.56Å; M171-Q379 HydrophobicContact SD-CG 3.8Å; L179-Q379 HydrophobicContact CD2-CB 3.92Å; G375-Q379 WeakPolarHBondContact O-CB 3.47Å; G375-Q379 PolarHBondContact O-N 3.04Å; C376-Q379 PolarHBondContact O-N 3.17Å; Q379-A381 VanDerWaalsContact C-N 3.35Å; Q379-I382 PolarHBondContact O-N 3.11Å; Q379-L383 HydrophobicContact CG-CD1 4.21Å; Q379-L383 WeakPolarHBondContact O-CG 3.44Å; Q379-L383 PolarHBondContact O-N 2.67Å; Q379-L383 VanDerWaalsContact O-N 3.14Å
380C96.2Very high92.7Very high0 Ų042.6 Ų42.60%022%0.221CC..Hα-helixtrans-65.7-38.2173.3-173.10000111.2V3 V4 V141 C376 A377 L378 L383 S384V3-C380 HydrophobicContact CG1-CB 4.06Å; V4-C380 PolarHBondContact N-SG 2.98Å; V4-C380 VanDerWaalsContact N-SG 3.41Å; V141-C380 HydrophobicContact CB-CB 4.19Å; V141-C380 HydrophobicContact CG2-CB 3.7Å; C376-C380 WeakPolarHBondContact O-CB 3.45Å; C376-C380 PolarHBondContact O-N 3.25Å; A377-C380 PolarHBondContact O-N 3.34Å; L378-C380 VanDerWaalsContact C-N 3.33Å; L378-C380 PolarHBondContact O-N 3.47Å; C380-L383 PolarHBondContact O-N 3.15Å; C380-S384 PolarHBondContact O-N 2.77Å
381A94.4Very high92.3Very high2 Ų250.4 Ų50.42%0.01726%0.257CS..Hα-helixtrans-64.2-44.7173.400000112.3V3 A377 L378 Q379 L383 S384 V389V3-A381 HydrophobicContact CG1-CB 3.9Å; V3-A381 HydrophobicContact CG2-CB 4.43Å; A377-A381 PolarHBondContact O-N 3.15Å; L378-A381 WeakPolarHBondContact O-CB 3.18Å; L378-A381 PolarHBondContact O-N 2.84Å; Q379-A381 VanDerWaalsContact C-N 3.35Å; A381-L383 PolarHBondContact O-N 3.32Å; A381-S384 WeakPolarHBondContact O-CB 3.5Å; A381-S384 PolarHBondContact O-N 3.37Å; A381-V389 HydrophobicContact CB-CG1 3.66Å
382I93.7Very high92.1Very high54 Ų5450.9 Ų50.928%0.27726%0.259SS..Hα-helixtrans-59.1-32.5175.7-68.8166.3000112L179 L378 Q379 V389 I394L179-I382 HydrophobicContact CD1-CD1 4.17Å; L179-I382 HydrophobicContact CD2-CD1 4.09Å; L378-I382 WeakPolarHBondContact O-CG1 3.45Å; L378-I382 PolarHBondContact O-N 3.37Å; Q379-I382 PolarHBondContact O-N 3.11Å; I382-V389 HydrophobicContact CB-CG2 4.3Å; I382-V389 HydrophobicContact CG1-CG2 3.67Å; I382-I394 HydrophobicContact CD1-CD1 4.18Å
383L93.2Very high91.9Very high76 Ų7653.3 Ų53.340%0.39828%0.277SS..THydrogen-bonded Turntrans-87.9-3.7178.4-65.6168.5000113.4V141 L168 R169 Q379 C380 A381V141-L383 HydrophobicContact CG2-CD1 4.32Å; L168-L383 HydrophobicContact CB-CD1 3.91Å; L168-L383 HydrophobicContact CD1-CB 3.99Å; R169-L383 HydrophobicContact CB-CD1 3.96Å; Q379-L383 HydrophobicContact CG-CD1 4.21Å; Q379-L383 WeakPolarHBondContact O-CG 3.44Å; Q379-L383 PolarHBondContact O-N 2.67Å; Q379-L383 VanDerWaalsContact O-N 3.14Å; C380-L383 PolarHBondContact O-N 3.15Å; A381-L383 PolarHBondContact O-N 3.32Å
384S89.7Confident91.8Very high8 Ų854.6 Ų54.66%0.05628%0.283CS..  trans-93.1121.2-175.3-169.10000112.1M1 C380 A381 A386 F387M1-S384 PolarHBondContact SD-OG 2.9Å; C380-S384 PolarHBondContact O-N 2.77Å; A381-S384 WeakPolarHBondContact O-CB 3.5Å; A381-S384 PolarHBondContact O-N 3.37Å; S384-A386 PolarHBondContact O-N 2.98Å; S384-A386 PolarHBondContact OG-N 3.4Å; S384-F387 PolarHBondContact O-N 3.44Å
385P87.3Confident91.8Very high124 Ų12453.9 Ų53.981%0.80529%0.286SS*.THydrogen-bonded Turntrans-66.8-10.3174.829.3-35.9000113.2
386A85.3Confident91.7Very high71 Ų7154.3 Ų54.359%0.58729%0.288SS*.THydrogen-bonded Turntrans-93.2-15.1179.900000114.1S384S384-A386 PolarHBondContact O-N 2.98Å; S384-A386 PolarHBondContact OG-N 3.4Å
387F83.3Confident91.6Very high83 Ų8354.8 Ų54.836%0.36429%0.291SS..  trans-118.1108.8-174.9-75.8-99000111.2V3 A18 S384 V389V3-F387 HydrophobicContact CB-CE2 4.3Å; V3-F387 HydrophobicContact CB-CZ 4.5Å; V3-F387 HydrophobicContact CG2-CD2 3.42Å; V3-F387 VanDerWaalsContact CG2-CD2 3.42Å; V3-F387 HydrophobicContact CG2-CE2 3.52Å; V3-F387 HydrophobicContact CG2-CG 3.97Å; V3-F387 HydrophobicContact CG2-CZ 4.13Å; A18-F387 HydrophobicContact CB-CD1 4.3Å; A18-F387 HydrophobicContact CB-CE1 3.7Å; A18-F387 HydrophobicContact CB-CZ 4.13Å; S384-F387 PolarHBondContact O-N 3.44Å; F387-V389 PolarHBondContact O-N 2.68Å
388K82Confident91.4Very high220 Ų22055 Ų5596%0.95729%0.293SS*.  trans-75.3103.8169.6-69.8-174.1177.8-177.20109.5
389V86.2Confident91.2Very high62 Ų6255.2 Ų55.238%0.37629%0.294SS..  trans-105.8165.5172.1-66.90000111.2A381 I382 F387 E391A381-V389 HydrophobicContact CB-CG1 3.66Å; I382-V389 HydrophobicContact CB-CG2 4.3Å; I382-V389 HydrophobicContact CG1-CG2 3.67Å; F387-V389 PolarHBondContact O-N 2.68Å; V389-E391 PolarHBondContact O-N 2.68Å
390R85.8Confident91Very high88 Ų8855.6 Ų55.633%0.33230%0.296SS..  trans-57.1129.9171.3-174.9-171.5-163.716715.3109.6I183 K185 Q186 F392I183-R390 HydrophobicContact CG1-CB 4.44Å; I183-R390 PolarHBondContact O-NH1 3.01Å; K185-R390 PolarHBondContact O-NH1 2.74Å; Q186-R390 VanDerWaalsContact OE1-CZ 3.29Å; R390-F392 PolarHBondContact O-N 3.33Å
391E86.6Confident90.9Very high179 Ų17956.4 Ų56.484%0.83630%0.302SS*.  trans-57.8121.7173.1-67.6-173175.300110.5V389V389-E391 PolarHBondContact O-N 2.68Å
392F92.4Very high91Very high12 Ų1256.5 Ų56.55%0.05330%0.302CS..  trans-146.8102.3-178.3-161.7-88.4000109.9L179 I183 F215 G218 L220 R390 I394L179-F392 HydrophobicContact CD1-CD1 3.34Å; L179-F392 HydrophobicContact CD1-CE1 3.63Å; L179-F392 HydrophobicContact CD1-CG 4.16Å; I183-F392 HydrophobicContact CB-CD2 4.19Å; I183-F392 HydrophobicContact CB-CE2 4.48Å; I183-F392 HydrophobicContact CB-CG 4.36Å; I183-F392 HydrophobicContact CD1-CB 3.99Å; I183-F392 HydrophobicContact CD1-CG 4.39Å; I183-F392 HydrophobicContact CG1-CB 4.17Å; I183-F392 HydrophobicContact CG1-CD2 4.08Å; I183-F392 HydrophobicContact CG1-CG 4.17Å; F215-F392 HydrophobicContact CD1-CZ 4.32Å; F215-F392 HydrophobicContact CE1-CZ 4.4Å; G218-F392 WeakPolarHBondContact O-CA 3.38Å; L220-F392 HydrophobicContact CB-CE1 3.51Å; L220-F392 HydrophobicContact CB-CZ 3.9Å; L220-F392 HydrophobicContact CD2-CE1 4.4Å; R390-F392 PolarHBondContact O-N 3.33Å; F392-I394 HydrophobicContact CD1-CG1 3.95Å; F392-I394 HydrophobicContact CE1-CG1 4.3Å
393S93.8Very high91.1Very high63 Ų6354 Ų5444%0.44129%0.289SS..EExtended strand (participates in β ladder)trans-77.6137.5-179.459.20000111.3G218 K219 L220G218-S393 PolarHBondContact O-N 3Å; G218-S393 PolarHBondContact O-OG 3.09Å; K219-S393 WeakPolarHBondContact CA-O 3.49Å; K219-S393 WeakPolarHBondContact CA-OG 3.5Å; L220-S393 PolarHBondContact N-O 3.27Å
394I96.2Very high91.2Very high26 Ų2650.4 Ų50.413%0.13327%0.27CS..EExtended strand (participates in β ladder)trans-129.7114.3-174.8-56.3158.3000108.7M171 T175 L179 L220 I382 F392M171-I394 HydrophobicContact CE-CD1 4.49Å; T175-I394 HydrophobicContact CG2-CG2 3.94Å; L179-I394 HydrophobicContact CD1-CD1 3.84Å; L179-I394 HydrophobicContact CD1-CG1 4.28Å; L179-I394 HydrophobicContact CD2-CD1 3.77Å; L179-I394 HydrophobicContact CG-CD1 4.27Å; L220-I394 HydrophobicContact CD2-CG2 4.17Å; L220-I394 WeakPolarHBondContact O-CA 3.36Å; I382-I394 HydrophobicContact CD1-CD1 4.18Å; F392-I394 HydrophobicContact CD1-CG1 3.95Å; F392-I394 HydrophobicContact CE1-CG1 4.3Å
395T96.4Very high91.3Very high48 Ų4852.7 Ų52.729%0.29428%0.279SS..EExtended strand (participates in β ladder)trans-104.7113.1170.1-54.30000109L220 K221 I222 A425L220-T395 PolarHBondContact O-N 2.84Å; K221-T395 HydrophobicContact CG-CG2 4.31Å; I222-T395 PolarHBondContact N-O 3.2Å; T395-A425 HydrophobicContact CG2-CB 3.73Å
396D96.6Very high91.5Very high9 Ų948.5 Ų48.55%0.04825%0.247CC..EExtended strand (participates in β ladder)trans-91.2-179.5176.8-149.6-30.7000109.8R169 N172 A425 A426R169-D396 IonicContact NH2-OD2 3.17Å; R169-D396 PolarHBondContact NH2-OD2 2.73Å; N172-D396 PolarHBondContact ND2-OD1 3.45Å; N172-D396 PolarHBondContact ND2-OD2 3.16Å; D396-A425 CarbonylContact O-C 3.57Å; D396-A425 WeakPolarHBondContact O-CA 3.15Å; D396-A426 PolarHBondContact N-O 3.29Å; D396-A426 VanDerWaalsContact N-O 3.12Å; D396-A426 PolarHBondContact O-N 2.82Å
397V95.8Very high91.5Very high9 Ų950.5 Ų50.56%0.05525%0.248CC..EExtended strand (participates in β ladder)trans-131.8151.6-179.5-70.90000113.6I222 N423 H424I222-V397 HydrophobicContact CB-CG1 4.12Å; I222-V397 HydrophobicContact CB-CG2 4.06Å; I222-V397 HydrophobicContact CG2-CG1 4.36Å; I222-V397 HydrophobicContact CG2-CG2 3.63Å; I222-V397 WeakPolarHBondContact O-CG1 3.4Å; V397-N423 HydrophobicContact CG1-CB 4.48Å; V397-H424 CarbonylContact C-O 3.52Å; V397-H424 WeakPolarHBondContact CA-O 3.41Å
398V93.5Very high90.8Very high6 Ų648 Ų484%0.03624%0.241CC..  trans-80.5121.4171.1-166.90000109.5Y400 I402 N423 H424 A426 V484V398-Y400 WeakPolarHBondContact CG1-O 3.49Å; V398-Y400 PolarHBondContact O-N 3.06Å; V398-I402 HydrophobicContact CG1-CD1 4.14Å; V398-N423 PolarHBondContact O-N 3.08Å; V398-H424 HydrophobicContact CG2-CB 4.34Å; V398-H424 PolarHBondContact N-O 3.13Å; V398-A426 HydrophobicContact CG2-CB 4.08Å; V398-V484 HydrophobicContact CG2-CB 4.43Å; V398-V484 HydrophobicContact CG2-CG1 4.22Å; V398-V484 HydrophobicContact CG2-CG2 4.17Å
399P90Very high89.8Confident14 Ų1441.5 Ų41.59%0.09123%0.228CC..SBendtrans-74-23.7-174.730.3-37.8000114S146 K422S146-P399 WeakPolarHBondContact O-CB 3.33Å; S146-P399 WeakPolarHBondContact O-CG 3.45Å; P399-K422 WeakPolarHBondContact O-CE 3.22Å
400Y93.4Very high88.6Confident13 Ų1343.2 Ų43.25%0.05125%0.249CC..SBendtrans-128.3141.7-175.8-59.1-62.7000110.6Y147 T149 F227 V398 Y446 E451 L452Y147-Y400 WeakPolarHBondContact O-CE2 3.44Å; Y147-Y400 PolarHBondContact O-OH 3.42Å; Y147-Y400 VanDerWaalsContact O-OH 3.07Å; T149-Y400 HydrophobicContact CG2-CE2 4.09Å; F227-Y400 AromaticContact CZ-CE1 3.8Å; F227-Y400 HydrophobicContact CZ-CE1 3.8Å; F227-Y400 AromaticContact CZ-CZ 3.86Å; F227-Y400 WeakPolarHBondContact CZ-OH 3.43Å; V398-Y400 WeakPolarHBondContact CG1-O 3.49Å; V398-Y400 PolarHBondContact O-N 3.06Å; Y400-Y446 VanDerWaalsContact CB-CD1 3.5Å; Y400-Y446 HydrophobicContact CD2-CE1 4.1Å; Y400-Y446 HydrophobicContact CG-CD1 4.25Å; Y400-Y446 HydrophobicContact CG-CE1 4.22Å; Y400-E451 WeakPolarHBondContact CE1-O 3.41Å; Y400-L452 HydrophobicContact CD1-CD1 4.4Å; Y400-L452 HydrophobicContact CD2-CD1 4.36Å; Y400-L452 HydrophobicContact CE1-CD1 4.29Å; Y400-L452 HydrophobicContact CE2-CD1 4.25Å; Y400-L452 HydrophobicContact CG-CD1 4.44Å
401S93.9Very high87.2Confident18 Ų1844.8 Ų44.813%0.12626%0.26CS..  trans-71132.8173.530.20000111.7E418 F420 Y446 N447S401-E418 WeakPolarHBondContact CB-OE1 3.24Å; S401-F420 CarbonylContact C-O 3.57Å; S401-F420 WeakPolarHBondContact CA-O 3.44Å; S401-Y446 WeakPolarHBondContact O-CA 3.26Å; S401-N447 PolarHBondContact O-N 3.37Å
402I95.8Very high85.5Confident4 Ų445.3 Ų45.32%0.02127%0.269CS..EExtended strand (participates in β ladder)trans-119.5120.9-177.4-55.6173.5000110.2V398 V419 F420 Y445 Y446 I459 V484 F490V398-I402 HydrophobicContact CG1-CD1 4.14Å; I402-V419 PolarHBondContact O-N 3.11Å; I402-F420 HydrophobicContact CB-CB 4.42Å; I402-F420 HydrophobicContact CB-CD2 4.43Å; I402-F420 PolarHBondContact N-O 3.36Å; I402-F420 PolarHBondContact O-N 3.22Å; I402-F420 VanDerWaalsContact O-N 3.12Å; I402-Y445 WeakPolarHBondContact CA-O 3.48Å; I402-Y446 HydrophobicContact CD1-CE1 4.39Å; I402-Y446 HydrophobicContact CG1-CD1 4.07Å; I402-Y446 HydrophobicContact CG1-CE1 4.01Å; I402-I459 HydrophobicContact CD1-CD1 4.11Å; I402-I459 HydrophobicContact CG1-CD1 4.04Å; I402-I459 HydrophobicContact CG2-CD1 3.82Å; I402-V484 HydrophobicContact CD1-CG2 4.27Å; I402-F490 HydrophobicContact CD1-CD2 4.45Å; I402-F490 HydrophobicContact CG2-CD2 4Å; I402-F490 HydrophobicContact CG2-CE2 4.25Å
403S95.7Very high84.2Confident2 Ų246.8 Ų46.81%0.01429%0.287CS..EExtended strand (participates in β ladder)trans-102.8166.3166.4-790000112.5C417 E418 A444 Y445 N447S403-C417 VanDerWaalsContact CA-O 3.25Å; S403-C417 WeakPolarHBondContact CA-O 3.41Å; S403-C417 WeakPolarHBondContact CB-O 3.47Å; S403-C417 PolarHBondContact OG-O 3.28Å; S403-E418 VanDerWaalsContact OG-CA 3.23Å; S403-E418 WeakPolarHBondContact OG-CA 3.19Å; S403-E418 PolarHBondContact OG-N 3.23Å; S403-A444 WeakPolarHBondContact O-CA 3.3Å; S403-Y445 VanDerWaalsContact CB-CZ 3.47Å; S403-Y445 WeakPolarHBondContact CB-OH 3.38Å; S403-Y445 PolarHBondContact N-O 3.21Å; S403-Y445 PolarHBondContact O-N 3.44Å; S403-Y445 VanDerWaalsContact O-N 3.15Å; S403-N447 WeakPolarHBondContact CB-OD1 3.44Å; S403-N447 PolarHBondContact N-OD1 3.38Å; S403-N447 VanDerWaalsContact N-OD1 3.16Å; S403-N447 VanDerWaalsContact OG-CG 3.29Å; S403-N447 PolarHBondContact OG-ND2 2.79Å; S403-N447 PolarHBondContact OG-OD1 3.41Å
404L95.1Very high83.3Confident0 Ų049.3 Ų49.30%030%0.295CS..EExtended strand (participates in β ladder)trans-116.6143.1159.9-68.8165.1000109.1W406 D416 C417 V419 L432 L442 E443 A444 V482 F490L404-W406 HydrophobicContact CB-CE3 4.28Å; L404-W406 HydrophobicContact CB-CZ3 4.12Å; L404-D416 CarbonylContact O-C 3.54Å; L404-D416 VanDerWaalsContact O-CA 3.25Å; L404-D416 WeakPolarHBondContact O-CA 3.38Å; L404-C417 PolarHBondContact N-O 3.18Å; L404-C417 PolarHBondContact O-N 2.77Å; L404-V419 HydrophobicContact CB-CG2 4.14Å; L404-V419 HydrophobicContact CD1-CG2 3.63Å; L404-V419 HydrophobicContact CG-CG2 3.7Å; L404-L432 HydrophobicContact CD1-CD1 3.63Å; L404-L442 HydrophobicContact CD1-CD1 4.47Å; L404-L442 HydrophobicContact CD2-CB 4.32Å; L404-E443 WeakPolarHBondContact CA-O 3.29Å; L404-A444 HydrophobicContact CD2-CB 3.68Å; L404-V482 HydrophobicContact CD1-CB 4.45Å; L404-V482 HydrophobicContact CD1-CG1 3.89Å; L404-V482 HydrophobicContact CD1-CG2 4.2Å; L404-F490 HydrophobicContact CD1-CZ 4.27Å; L404-F490 HydrophobicContact CD2-CE1 4.31Å; L404-F490 HydrophobicContact CD2-CZ 3.78Å; L404-F490 HydrophobicContact CG-CZ 4.32Å
405K93.3Very high82.7Confident56 Ų5649 Ų4924%0.24330%0.295CS..EExtended strand (participates in β ladder)trans-123.4152169.861.2-175.1174.7173.70110.9L414 S415 D416 E443 Y445K405-L414 HydrophobicContact CB-CD2 4.36Å; K405-L414 HydrophobicContact CD-CD2 4.31Å; K405-L414 HydrophobicContact CG-CD2 4.32Å; K405-S415 WeakPolarHBondContact CA-O 3.45Å; K405-D416 HydrophobicContact CB-CB 3.97Å; K405-E443 WeakPolarHBondContact CE-OE1 3.3Å; K405-E443 WeakPolarHBondContact CE-OE2 3.41Å; K405-E443 HydrophobicContact CG-CB 4.06Å; K405-E443 PolarHBondContact N-O 3.46Å; K405-E443 IonicContact NZ-OE1 3.96Å; K405-E443 PolarHBondContact NZ-OE1 2.8Å; K405-E443 IonicContact NZ-OE2 3.72Å; K405-E443 PolarHBondContact NZ-OE2 2.96Å; K405-E443 PolarHBondContact O-N 2.75Å; K405-E443 VanDerWaalsContact O-N 3.08Å; K405-Y445 HydrophobicContact CB-CE1 3.73Å; K405-Y445 HydrophobicContact CD-CD1 3.96Å; K405-Y445 HydrophobicContact CD-CE1 3.72Å; K405-Y445 HydrophobicContact CG-CD1 3.97Å; K405-Y445 HydrophobicContact CG-CE1 3.61Å
406W91.8Very high82.4Confident36 Ų3651.4 Ų51.414%0.13631%0.306CS..EExtended strand (participates in β ladder)trans-155.3151.9-178.258.475.6000111.5L404 S408 L414 S415 C417 F434 L442L404-W406 HydrophobicContact CB-CE3 4.28Å; L404-W406 HydrophobicContact CB-CZ3 4.12Å; W406-S408 PolarHBondContact O-N 3.13Å; W406-L414 CarbonylContact O-C 3.49Å; W406-L414 VanDerWaalsContact O-CA 3.31Å; W406-L414 WeakPolarHBondContact O-CA 3.35Å; W406-S415 PolarHBondContact N-O 3.43Å; W406-S415 PolarHBondContact O-N 2.91Å; W406-C417 HydrophobicContact CH2-CB 3.62Å; W406-C417 HydrophobicContact CZ3-CB 4.02Å; W406-F434 HydrophobicContact CD2-CD1 4.4Å; W406-F434 AromaticContact CD2-CE1 3.64Å; W406-F434 HydrophobicContact CD2-CE1 3.64Å; W406-F434 HydrophobicContact CD2-CZ 4.45Å; W406-F434 AromaticContact CE2-CE1 3.73Å; W406-F434 AromaticContact CE3-CE1 3.67Å; W406-F434 HydrophobicContact CE3-CE1 3.67Å; W406-F434 HydrophobicContact CE3-CZ 4.08Å; W406-F434 HydrophobicContact CG-CE1 4.35Å; W406-F434 AromaticContact CH2-CE1 3.88Å; W406-F434 HydrophobicContact CH2-CE1 3.88Å; W406-F434 HydrophobicContact CH2-CZ 4.49Å; W406-F434 AromaticContact CZ2-CE1 3.86Å; W406-F434 HydrophobicContact CZ2-CE1 3.86Å; W406-F434 AromaticContact CZ3-CE1 3.8Å; W406-F434 HydrophobicContact CZ3-CE1 3.8Å; W406-F434 HydrophobicContact CZ3-CZ 4.11Å; W406-L442 HydrophobicContact CB-CD2 3.84Å; W406-L442 HydrophobicContact CD2-CD2 4.32Å; W406-L442 HydrophobicContact CE3-CD2 3.91Å; W406-L442 HydrophobicContact CG-CD2 4.34Å
407N83.5Confident82.1Confident112 Ų11253.3 Ų53.360%0.59932%0.319SS*.EExtended strand (participates in β ladder)trans-69.3122.2171.9-58.6-4.3000108.7R436N407-R436 PolarHBondContact O-NH1 3.2Å; N407-R436 PolarHBondContact O-NH2 2.78Å
408S69.1Low82.1Confident32 Ų3256.8 Ų56.822%0.22434%0.335CS..  trans-75.6168.3179.4-164.70000111.9W406 A410 E411 G413 S415W406-S408 PolarHBondContact O-N 3.13Å; S408-A410 PolarHBondContact OG-N 2.85Å; S408-E411 WeakPolarHBondContact CB-O 3.45Å; S408-E411 PolarHBondContact OG-N 3.01Å; S408-G413 PolarHBondContact N-O 3.4Å; S408-S415 WeakPolarHBondContact CB-OG 3.32Å
409A62.1Low82.2Confident82 Ų8256.6 Ų56.668%0.67833%0.334SS*.SBendtrans-124.78.617000000111.9
410A60.1Low82.5Confident98 Ų9856 Ų5681%0.8133%0.33SS*.SBendtrans-129.5-5.717800000112.6S408S408-A410 PolarHBondContact OG-N 2.85Å
411E57.3Low82.5Confident122 Ų12257.7 Ų57.757%0.5734%0.342SS*.SBendtrans-136.3138175.2-61172.113700106.6S408 G413 S415S408-E411 WeakPolarHBondContact CB-O 3.45Å; S408-E411 PolarHBondContact OG-N 3.01Å; E411-G413 PolarHBondContact O-N 3.27Å; E411-S415 PolarHBondContact OE2-OG 3.02Å
412D50.8Low82.5Confident190 Ų19059.5 Ų59.5100%1.01635%0.348SS*.SBendtrans-76.674.6175.8-76.3-47.9000110.6
413G63.9Low82.4Confident43 Ų4361 Ų6144%0.44336%0.356SS..SBendtrans174.1-173.4179.800000115.7S408 E411S408-G413 PolarHBondContact N-O 3.4Å; E411-G413 PolarHBondContact O-N 3.27Å
414L75.2Confident82.4Confident116 Ų11663.1 Ų63.161%0.60737%0.366SS*.EExtended strand (participates in β ladder)trans-84.1124.9163.8-75.6117.2000109.2K405 W406K405-L414 HydrophobicContact CB-CD2 4.36Å; K405-L414 HydrophobicContact CD-CD2 4.31Å; K405-L414 HydrophobicContact CG-CD2 4.32Å; W406-L414 CarbonylContact O-C 3.49Å; W406-L414 VanDerWaalsContact O-CA 3.31Å; W406-L414 WeakPolarHBondContact O-CA 3.35Å
415S83.7Confident82.4Confident18 Ų1864.8 Ų64.813%0.12638%0.379CS..EExtended strand (participates in β ladder)trans-93.3147.9163-31.80000109K405 W406 S408 E411K405-S415 WeakPolarHBondContact CA-O 3.45Å; W406-S415 PolarHBondContact N-O 3.43Å; W406-S415 PolarHBondContact O-N 2.91Å; S408-S415 WeakPolarHBondContact CB-OG 3.32Å; E411-S415 PolarHBondContact OE2-OG 3.02Å
416D89Confident82.5Confident100 Ų10062.5 Ų62.554%0.53537%0.371SS..EExtended strand (participates in β ladder)trans-126.3167.7172.176-39.3000113.1L404 K405 Y445L404-D416 CarbonylContact O-C 3.54Å; L404-D416 VanDerWaalsContact O-CA 3.25Å; L404-D416 WeakPolarHBondContact O-CA 3.38Å; K405-D416 HydrophobicContact CB-CB 3.97Å; D416-Y445 VanDerWaalsContact CB-OH 3.23Å; D416-Y445 WeakPolarHBondContact CB-OH 3.45Å; D416-Y445 PolarHBondContact OD2-OH 3.06Å
417C92.3Very high82.6Confident48 Ų4863.4 Ų63.432%0.32438%0.381SS..EExtended strand (participates in β ladder)trans-158.2130.3176.5-179.10000111.7S403 L404 W406 V419S403-C417 VanDerWaalsContact CA-O 3.25Å; S403-C417 WeakPolarHBondContact CA-O 3.41Å; S403-C417 WeakPolarHBondContact CB-O 3.47Å; S403-C417 PolarHBondContact OG-O 3.28Å; L404-C417 PolarHBondContact N-O 3.18Å; L404-C417 PolarHBondContact O-N 2.77Å; W406-C417 HydrophobicContact CH2-CB 3.62Å; W406-C417 HydrophobicContact CZ3-CB 4.02Å; C417-V419 PolarHBondContact O-N 3.14Å
418E94.6Very high83.3Confident83 Ų8362.6 Ų62.639%0.38837%0.373SS..EExtended strand (participates in β ladder)trans-69117.2171.8-170169-105.800110.9S401 S403 P421 K430 N447S401-E418 WeakPolarHBondContact CB-OE1 3.24Å; S403-E418 VanDerWaalsContact OG-CA 3.23Å; S403-E418 WeakPolarHBondContact OG-CA 3.19Å; S403-E418 PolarHBondContact OG-N 3.23Å; E418-P421 WeakPolarHBondContact OE2-CB 3.43Å; E418-K430 PolarHBondContact O-NZ 3.3Å; E418-N447 WeakPolarHBondContact CG-ND2 3.46Å; E418-N447 PolarHBondContact OE1-ND2 3.28Å
419V95.2Very high84.6Confident1 Ų163 Ų631%0.00638%0.376CS..EExtended strand (participates in β ladder)trans-89.7-51.7-177.4-172.60000109.2I402 L404 C417 K430 L432 V482I402-V419 PolarHBondContact O-N 3.11Å; L404-V419 HydrophobicContact CB-CG2 4.14Å; L404-V419 HydrophobicContact CD1-CG2 3.63Å; L404-V419 HydrophobicContact CG-CG2 3.7Å; C417-V419 PolarHBondContact O-N 3.14Å; V419-K430 HydrophobicContact CB-CD 4.44Å; V419-K430 HydrophobicContact CG1-CB 4.09Å; V419-K430 HydrophobicContact CG1-CD 3.67Å; V419-K430 WeakPolarHBondContact O-CD 3.2Å; V419-K430 PolarHBondContact O-NZ 3.06Å; V419-L432 HydrophobicContact CG2-CD1 4.3Å; V419-V482 HydrophobicContact CG1-CG2 3.47Å; V419-V482 VanDerWaalsContact CG1-CG2 3.47Å
420F96.1Very high86.2Confident1 Ų162.5 Ų62.50%0.00436%0.358CS..EExtended strand (participates in β ladder)trans-128.5103.5-177.3-56.9-81000109S401 I402 H424 F428 V482 V484 F490S401-F420 CarbonylContact C-O 3.57Å; S401-F420 WeakPolarHBondContact CA-O 3.44Å; I402-F420 HydrophobicContact CB-CB 4.42Å; I402-F420 HydrophobicContact CB-CD2 4.43Å; I402-F420 PolarHBondContact N-O 3.36Å; I402-F420 PolarHBondContact O-N 3.22Å; I402-F420 VanDerWaalsContact O-N 3.12Å; F420-H424 HydrophobicContact CB-CB 4.41Å; F420-H424 AromaticContact CD1-ND1 4Å; F420-F428 HydrophobicContact CE1-CB 4.2Å; F420-F428 HydrophobicContact CE1-CD1 4.02Å; F420-V482 HydrophobicContact CE2-CG2 4.49Å; F420-V484 HydrophobicContact CD1-CG2 4.14Å; F420-V484 HydrophobicContact CD2-CG2 3.79Å; F420-V484 HydrophobicContact CE1-CG2 4.15Å; F420-V484 HydrophobicContact CE2-CG2 3.81Å; F420-V484 HydrophobicContact CG-CG2 3.96Å; F420-V484 HydrophobicContact CZ-CG2 4.01Å; F420-F490 HydrophobicContact CD2-CD2 4.32Å; F420-F490 HydrophobicContact CD2-CE2 4.34Å; F420-F490 AromaticContact CE2-CD2 3.98Å; F420-F490 HydrophobicContact CE2-CD2 3.98Å; F420-F490 AromaticContact CE2-CE2 3.84Å; F420-F490 HydrophobicContact CE2-CE2 3.84Å
421P94.9Very high87.9Confident49 Ų4961.9 Ų61.932%0.31834%0.344SS..  trans-63.2165.9172.822.5-32.7000112.4E418 H424E418-P421 WeakPolarHBondContact OE2-CB 3.43Å; P421-H424 HydrophobicContact CG-CB 4.11Å; P421-H424 WeakPolarHBondContact O-CB 3.2Å; P421-H424 PolarHBondContact O-N 3.4Å
422K92.8Very high89.6Confident56 Ų5657.2 Ų57.224%0.24332%0.323CS..THydrogen-bonded Turntrans-57.3140.5169.5-174.6171.8-174179.20110.5P399 H424 E451P399-K422 WeakPolarHBondContact O-CE 3.22Å; K422-H424 PolarHBondContact O-N 3.03Å; K422-E451 WeakPolarHBondContact CD-OE2 3.32Å; K422-E451 IonicContact NZ-OE2 2.67Å; K422-E451 PolarHBondContact NZ-OE2 3.21Å
423N94Very high91.6Very high35 Ų3551.2 Ų51.219%0.18729%0.293CS..THydrogen-bonded Turntrans60.215.8-171.6-56.6-42.9000115.6A224 A225 Q327 V397 V398 A425A224-N423 WeakPolarHBondContact CA-OD1 3.31Å; A225-N423 PolarHBondContact N-OD1 2.81Å; Q327-N423 PolarHBondContact OE1-ND2 2.78Å; V397-N423 HydrophobicContact CG1-CB 4.48Å; V398-N423 PolarHBondContact O-N 3.08Å; N423-A425 PolarHBondContact O-N 3.43Å
424H95.6Very high92.9Very high47 Ų4749.8 Ų49.822%0.21828%0.275CS..  trans-59.8140.9170.2-168.1-76.5000110.1V397 V398 F420 P421 K422 F428V397-H424 CarbonylContact C-O 3.52Å; V397-H424 WeakPolarHBondContact CA-O 3.41Å; V398-H424 HydrophobicContact CG2-CB 4.34Å; V398-H424 PolarHBondContact N-O 3.13Å; F420-H424 HydrophobicContact CB-CB 4.41Å; F420-H424 AromaticContact CD1-ND1 4Å; P421-H424 HydrophobicContact CG-CB 4.11Å; P421-H424 WeakPolarHBondContact O-CB 3.2Å; P421-H424 PolarHBondContact O-N 3.4Å; K422-H424 PolarHBondContact O-N 3.03Å; H424-F428 AromaticContact CE1-CD1 3.46Å; H424-F428 VanDerWaalsContact CE1-CD1 3.46Å; H424-F428 WeakPolarHBondContact CE1-CD1 3.44Å; H424-F428 AromaticContact CE1-CD2 3.93Å; H424-F428 AromaticContact CE1-CE1 3.92Å; H424-F428 AromaticContact CE1-CG 3.46Å; H424-F428 VanDerWaalsContact CE1-CG 3.46Å; H424-F428 WeakPolarHBondContact CE1-CG 3.4Å
425A95.9Very high93.6Very high35 Ų3550.2 Ų50.229%0.28927%0.269SS..EExtended strand (participates in β ladder)trans-58.9139.6177.600000111.8T395 D396 N423 F428T395-A425 HydrophobicContact CG2-CB 3.73Å; D396-A425 CarbonylContact O-C 3.57Å; D396-A425 WeakPolarHBondContact O-CA 3.15Å; N423-A425 PolarHBondContact O-N 3.43Å; A425-F428 WeakPolarHBondContact O-CB 3.48Å
426A94.4Very high93.9Very high8 Ų850.5 Ų50.57%0.06627%0.268CS..EExtended strand (participates in β ladder)trans-130.9143.5177.300000111D396 V398 V484D396-A426 PolarHBondContact N-O 3.29Å; D396-A426 VanDerWaalsContact N-O 3.12Å; D396-A426 PolarHBondContact O-N 2.82Å; V398-A426 HydrophobicContact CG2-CB 4.08Å; A426-V484 HydrophobicContact CB-CG1 4.28Å
427P95.4Very high93.8Very high55 Ų5551.1 Ų51.136%0.35727%0.265SS..SBendcis-73.8149.4-3.433-38.2000112.9V484 V486P427-V484 WeakPolarHBondContact CA-O 3.48Å; P427-V484 WeakPolarHBondContact CB-O 3.46Å; P427-V486 HydrophobicContact CB-CG1 4.36Å; P427-V486 HydrophobicContact CG-CG1 4.11Å
428F96.6Very high93.7Very high96 Ų9655.2 Ų55.242%0.42128%0.28SS..EExtended strand (participates in β ladder)trans-150.2154.4177.7-165.4-95.5000112.4F420 H424 A425 R483 V484F420-F428 HydrophobicContact CE1-CB 4.2Å; F420-F428 HydrophobicContact CE1-CD1 4.02Å; H424-F428 AromaticContact CE1-CD1 3.46Å; H424-F428 VanDerWaalsContact CE1-CD1 3.46Å; H424-F428 WeakPolarHBondContact CE1-CD1 3.44Å; H424-F428 AromaticContact CE1-CD2 3.93Å; H424-F428 AromaticContact CE1-CE1 3.92Å; H424-F428 AromaticContact CE1-CG 3.46Å; H424-F428 VanDerWaalsContact CE1-CG 3.46Å; H424-F428 WeakPolarHBondContact CE1-CG 3.4Å; A425-F428 WeakPolarHBondContact O-CB 3.48Å; F428-R483 WeakPolarHBondContact O-CA 3.31Å; F428-R483 WeakPolarHBondContact O-CG 3.46Å; F428-V484 PolarHBondContact N-O 3.13Å; F428-V484 VanDerWaalsContact N-O 3.07Å; F428-V484 PolarHBondContact O-N 3.48Å
429S96.8Very high93.6Very high41 Ų4154.5 Ų54.529%0.28728%0.282SS..EExtended strand (participates in β ladder)trans-128.9131.1177.2-58.50000111.6V482 R483S429-V482 CarbonylContact C-O 3.15Å; S429-V482 VanDerWaalsContact CA-O 3.3Å; S429-V482 WeakPolarHBondContact CA-O 3.46Å; S429-R483 WeakPolarHBondContact OG-CD 3.45Å; S429-R483 WeakPolarHBondContact OG-CG 3.48Å
430K95.4Very high93.5Very high71 Ų7155.1 Ų55.131%0.30929%0.285SS..EExtended strand (participates in β ladder)trans-113.9136.5176.5-158.1178.5-166.1172.40108.4E418 V419 L432 V482E418-K430 PolarHBondContact O-NZ 3.3Å; V419-K430 HydrophobicContact CB-CD 4.44Å; V419-K430 HydrophobicContact CG1-CB 4.09Å; V419-K430 HydrophobicContact CG1-CD 3.67Å; V419-K430 WeakPolarHBondContact O-CD 3.2Å; V419-K430 PolarHBondContact O-NZ 3.06Å; K430-L432 HydrophobicContact CD-CD2 4.33Å; K430-L432 HydrophobicContact CG-CD2 4.42Å; K430-V482 HydrophobicContact CB-CG2 4.26Å; K430-V482 PolarHBondContact N-O 3.42Å; K430-V482 WeakPolarHBondContact O-CG2 3.47Å; K430-V482 PolarHBondContact O-N 3.09Å
431V95.6Very high93.3Very high85 Ų8559.7 Ų59.752%0.51531%0.307SS..EExtended strand (participates in β ladder)trans-102.8118.7173.9-179.50000108.7K479 V480 K481V431-K479 HydrophobicContact CG1-CB 4.19Å; V431-K479 HydrophobicContact CG1-CG 4.48Å; V431-V480 WeakPolarHBondContact CA-O 3.3Å; V431-K481 HydrophobicContact CG2-CB 4.19Å; V431-K481 HydrophobicContact CG2-CG 4.05Å
432L93.9Very high93.3Very high23 Ų2357.3 Ų57.312%0.1229%0.292CS..EExtended strand (participates in β ladder)trans-98.2152.8173.5-58179.7000109.6L404 V419 K430 F434 K479 V480 V482L404-L432 HydrophobicContact CD1-CD1 3.63Å; V419-L432 HydrophobicContact CG2-CD1 4.3Å; K430-L432 HydrophobicContact CD-CD2 4.33Å; K430-L432 HydrophobicContact CG-CD2 4.42Å; L432-F434 HydrophobicContact CB-CE2 3.74Å; L432-F434 HydrophobicContact CB-CZ 3.87Å; L432-F434 HydrophobicContact CD1-CE2 4.48Å; L432-F434 HydrophobicContact CD1-CZ 4.01Å; L432-K479 WeakPolarHBondContact O-CA 3.37Å; L432-V480 PolarHBondContact N-O 2.86Å; L432-V480 PolarHBondContact O-N 3.15Å; L432-V482 HydrophobicContact CD1-CG2 4.29Å; L432-V482 HydrophobicContact CG-CG2 4.45Å
433T93.3Very high93.4Very high64 Ų6456.3 Ų56.339%0.39329%0.289SS..EExtended strand (participates in β ladder)trans-124.4120.5179.7-66.80000109Y435 K477 V478T433-Y435 HydrophobicContact CG2-CE2 3.94Å; T433-K477 HydrophobicContact CG2-CD 4.34Å; T433-K477 VanDerWaalsContact CG2-CE 3.46Å; T433-K477 HydrophobicContact CG2-CG 3.93Å; T433-V478 WeakPolarHBondContact CA-O 3.44Å
434F91Very high93.5Very high13 Ų1354.7 Ų54.76%0.05728%0.28CS..EExtended strand (participates in β ladder)trans-113.5154.5176.3-56.1-78.4000110.1W406 L432 R436 F440 L442 V478 V480W406-F434 HydrophobicContact CD2-CD1 4.4Å; W406-F434 AromaticContact CD2-CE1 3.64Å; W406-F434 HydrophobicContact CD2-CE1 3.64Å; W406-F434 HydrophobicContact CD2-CZ 4.45Å; W406-F434 AromaticContact CE2-CE1 3.73Å; W406-F434 AromaticContact CE3-CE1 3.67Å; W406-F434 HydrophobicContact CE3-CE1 3.67Å; W406-F434 HydrophobicContact CE3-CZ 4.08Å; W406-F434 HydrophobicContact CG-CE1 4.35Å; W406-F434 AromaticContact CH2-CE1 3.88Å; W406-F434 HydrophobicContact CH2-CE1 3.88Å; W406-F434 HydrophobicContact CH2-CZ 4.49Å; W406-F434 AromaticContact CZ2-CE1 3.86Å; W406-F434 HydrophobicContact CZ2-CE1 3.86Å; W406-F434 AromaticContact CZ3-CE1 3.8Å; W406-F434 HydrophobicContact CZ3-CE1 3.8Å; W406-F434 HydrophobicContact CZ3-CZ 4.11Å; L432-F434 HydrophobicContact CB-CE2 3.74Å; L432-F434 HydrophobicContact CB-CZ 3.87Å; L432-F434 HydrophobicContact CD1-CE2 4.48Å; L432-F434 HydrophobicContact CD1-CZ 4.01Å; F434-R436 HydrophobicContact CB-CG 4.15Å; F434-F440 HydrophobicContact CB-CE2 4.34Å; F434-F440 HydrophobicContact CB-CZ 4.03Å; F434-F440 HydrophobicContact CD1-CE2 4.31Å; F434-F440 AromaticContact CD2-CE2 3.94Å; F434-F440 HydrophobicContact CD2-CE2 3.94Å; F434-F440 AromaticContact CD2-CZ 3.73Å; F434-F440 HydrophobicContact CD2-CZ 3.73Å; F434-F440 HydrophobicContact CE2-CE2 4.31Å; F434-F440 HydrophobicContact CE2-CZ 4.4Å; F434-F440 AromaticContact CG-CE2 3.93Å; F434-F440 HydrophobicContact CG-CE2 3.93Å; F434-F440 AromaticContact CG-CZ 3.92Å; F434-F440 HydrophobicContact CG-CZ 3.92Å; F434-L442 HydrophobicContact CE1-CD2 4.21Å; F434-L442 HydrophobicContact CE2-CD1 4.07Å; F434-L442 HydrophobicContact CE2-CD2 4.25Å; F434-L442 HydrophobicContact CZ-CD1 4.25Å; F434-L442 HydrophobicContact CZ-CD2 3.79Å; F434-V478 PolarHBondContact N-O 3.07Å; F434-V478 PolarHBondContact O-N 3.48Å; F434-V480 HydrophobicContact CD2-CB 4.29Å; F434-V480 HydrophobicContact CD2-CG2 3.74Å; F434-V480 HydrophobicContact CE2-CB 3.96Å; F434-V480 HydrophobicContact CE2-CG2 3.83Å
435Y90.1Very high93.5Very high126 Ų12654 Ų5449%0.49428%0.275SS..EExtended strand (participates in β ladder)trans-118.8112.9172.7-65.1-83.5000108.1T433 S476 K477T433-Y435 HydrophobicContact CG2-CE2 3.94Å; Y435-S476 CarbonylContact C-O 3.58Å; Y435-S476 WeakPolarHBondContact CA-O 3.35Å; Y435-K477 HydrophobicContact CD1-CB 4.04Å; Y435-K477 HydrophobicContact CD1-CG 4.27Å; Y435-K477 HydrophobicContact CE1-CB 3.74Å; Y435-K477 HydrophobicContact CE1-CD 3.86Å; Y435-K477 HydrophobicContact CE1-CG 3.64Å; Y435-K477 WeakPolarHBondContact OH-CE 3.49Å; Y435-K477 PolarHBondContact OH-NZ 2.71Å
436R88.4Confident93.5Very high24 Ų2453.3 Ų53.39%0.09127%0.265CS..EExtended strand (participates in β ladder)trans-139.2149.3-166.8-67-66.9-177.6-173.10.4112.6N407 F434 F440 V467 S475 S476 V478N407-R436 PolarHBondContact O-NH1 3.2Å; N407-R436 PolarHBondContact O-NH2 2.78Å; F434-R436 HydrophobicContact CB-CG 4.15Å; R436-F440 HydrophobicContact CB-CD1 4.34Å; R436-F440 HydrophobicContact CG-CD1 3.68Å; R436-F440 HydrophobicContact CG-CE1 3.8Å; R436-F440 HydrophobicContact CG-CG 4.08Å; R436-F440 HydrophobicContact CG-CZ 4.26Å; R436-V467 HydrophobicContact CB-CG1 3.66Å; R436-S475 CarbonylContact O-C 3.56Å; R436-S475 WeakPolarHBondContact O-CA 3.5Å; R436-S476 PolarHBondContact N-O 3.29Å; R436-S476 PolarHBondContact O-N 3.41Å; R436-V478 HydrophobicContact CB-CG2 4.5Å
437K88.1Confident93.2Very high112 Ų11255.5 Ų55.549%0.48728%0.276SS..SBendtrans-102.4-21.1173.4-62.4-169.9-178.2-159.70113.2V468 P469 G473K437-V468 CarbonylContact O-C 3.54Å; K437-P469 HydrophobicContact CB-CB 4.28Å; K437-P469 HydrophobicContact CG-CB 4.4Å; K437-P469 VanDerWaalsContact O-CD 3.22Å; K437-P469 WeakPolarHBondContact O-CD 3Å; K437-G473 WeakPolarHBondContact CE-O 3.28Å; K437-G473 PolarHBondContact NZ-O 2.92Å
438E90.5Very high92.7Very high135 Ų13555.5 Ų55.563%0.63127%0.273SS*.SBendtrans-144.6165.4-169.569.2-162144.800110.5V467E438-V467 CarbonylContact C-O 3.52Å; E438-V467 WeakPolarHBondContact CA-O 3.26Å; E438-V467 WeakPolarHBondContact O-CB 3.3Å; E438-V467 WeakPolarHBondContact O-CG1 3.42Å
439P91.5Very high92.1Very high67 Ų6755.7 Ų55.744%0.43528%0.276SS..  trans-53.8143.5174.3-28.337.9000112.5L463 I464 V467P439-L463 HydrophobicContact CB-CD1 4.25Å; P439-I464 VanDerWaalsContact CA-O 3.31Å; P439-I464 WeakPolarHBondContact CA-O 3.45Å; P439-I464 WeakPolarHBondContact CB-O 3.28Å; P439-V467 WeakPolarHBondContact CD-O 3.24Å
440F92.5Very high91.4Very high15 Ų1563.1 Ų63.17%0.06630%0.304CS..EExtended strand (participates in β ladder)trans-143.7151.7-175.271.8-72000112.2F434 R436 L442 I464 V467 V478 V480F434-F440 HydrophobicContact CB-CE2 4.34Å; F434-F440 HydrophobicContact CB-CZ 4.03Å; F434-F440 HydrophobicContact CD1-CE2 4.31Å; F434-F440 AromaticContact CD2-CE2 3.94Å; F434-F440 HydrophobicContact CD2-CE2 3.94Å; F434-F440 AromaticContact CD2-CZ 3.73Å; F434-F440 HydrophobicContact CD2-CZ 3.73Å; F434-F440 HydrophobicContact CE2-CE2 4.31Å; F434-F440 HydrophobicContact CE2-CZ 4.4Å; F434-F440 AromaticContact CG-CE2 3.93Å; F434-F440 HydrophobicContact CG-CE2 3.93Å; F434-F440 AromaticContact CG-CZ 3.92Å; F434-F440 HydrophobicContact CG-CZ 3.92Å; R436-F440 HydrophobicContact CB-CD1 4.34Å; R436-F440 HydrophobicContact CG-CD1 3.68Å; R436-F440 HydrophobicContact CG-CE1 3.8Å; R436-F440 HydrophobicContact CG-CG 4.08Å; R436-F440 HydrophobicContact CG-CZ 4.26Å; F440-L442 HydrophobicContact CD2-CD2 4.17Å; F440-L442 HydrophobicContact CD2-CG 4.43Å; F440-L442 HydrophobicContact CE2-CD1 4.47Å; F440-L442 HydrophobicContact CE2-CD2 3.72Å; F440-L442 HydrophobicContact CE2-CG 3.95Å; F440-I464 HydrophobicContact CD1-CB 4.18Å; F440-I464 HydrophobicContact CE1-CB 3.85Å; F440-I464 HydrophobicContact CE1-CD1 4.41Å; F440-I464 HydrophobicContact CE1-CG1 4.24Å; F440-I464 HydrophobicContact CE1-CG2 4.1Å; F440-I464 HydrophobicContact CE2-CD1 4.23Å; F440-I464 HydrophobicContact CZ-CB 4.36Å; F440-I464 HydrophobicContact CZ-CD1 4.12Å; F440-I464 HydrophobicContact CZ-CG1 4.24Å; F440-I464 PolarHBondContact N-O 3.33Å; F440-I464 PolarHBondContact O-N 3.19Å; F440-V467 HydrophobicContact CD1-CG2 4.16Å; F440-V467 HydrophobicContact CE1-CG2 4.13Å; F440-V478 HydrophobicContact CE1-CG1 4.35Å; F440-V480 HydrophobicContact CZ-CG2 4.29Å
441M93.1Very high90.7Very high96 Ų9663.6 Ų63.647%0.47331%0.307SS..EExtended strand (participates in β ladder)trans-94.8138.9177.7-168.6-179.8-72.100110.9E461 F462M441-E461 HydrophobicContact CG-CB 4.46Å; M441-E461 HydrophobicContact SD-CB 4.07Å; M441-E461 HydrophobicContact SD-CG 4.06Å; M441-F462 CarbonylContact C-O 3.52Å; M441-F462 WeakPolarHBondContact CA-O 3.39Å
442L94.5Very high90.2Very high0 Ų060 Ų600%029%0.285CS..EExtended strand (participates in β ladder)trans-111.7125.7162.4-65.4-178.5000108.2L404 W406 F434 F440 F462 I464 V480L404-L442 HydrophobicContact CD1-CD1 4.47Å; L404-L442 HydrophobicContact CD2-CB 4.32Å; W406-L442 HydrophobicContact CB-CD2 3.84Å; W406-L442 HydrophobicContact CD2-CD2 4.32Å; W406-L442 HydrophobicContact CE3-CD2 3.91Å; W406-L442 HydrophobicContact CG-CD2 4.34Å; F434-L442 HydrophobicContact CE1-CD2 4.21Å; F434-L442 HydrophobicContact CE2-CD1 4.07Å; F434-L442 HydrophobicContact CE2-CD2 4.25Å; F434-L442 HydrophobicContact CZ-CD1 4.25Å; F434-L442 HydrophobicContact CZ-CD2 3.79Å; F440-L442 HydrophobicContact CD2-CD2 4.17Å; F440-L442 HydrophobicContact CD2-CG 4.43Å; F440-L442 HydrophobicContact CE2-CD1 4.47Å; F440-L442 HydrophobicContact CE2-CD2 3.72Å; F440-L442 HydrophobicContact CE2-CG 3.95Å; L442-F462 PolarHBondContact N-O 2.97Å; L442-F462 PolarHBondContact O-N 2.73Å; L442-I464 HydrophobicContact CB-CD1 4.37Å; L442-I464 HydrophobicContact CD1-CD1 3.83Å; L442-I464 HydrophobicContact CG-CD1 3.74Å; L442-V480 HydrophobicContact CD1-CG1 4.03Å
443E95.4Very high89.7Confident35 Ų3561.7 Ų61.716%0.16429%0.294CS..EExtended strand (participates in β ladder)trans-104.8126.8168.8-167.6-165.7130.700109.6L404 K405 T458 G460 E461L404-E443 WeakPolarHBondContact CA-O 3.29Å; K405-E443 WeakPolarHBondContact CE-OE1 3.3Å; K405-E443 WeakPolarHBondContact CE-OE2 3.41Å; K405-E443 HydrophobicContact CG-CB 4.06Å; K405-E443 PolarHBondContact N-O 3.46Å; K405-E443 IonicContact NZ-OE1 3.96Å; K405-E443 PolarHBondContact NZ-OE1 2.8Å; K405-E443 IonicContact NZ-OE2 3.72Å; K405-E443 PolarHBondContact NZ-OE2 2.96Å; K405-E443 PolarHBondContact O-N 2.75Å; K405-E443 VanDerWaalsContact O-N 3.08Å; E443-T458 HydrophobicContact CG-CG2 3.74Å; E443-T458 WeakPolarHBondContact OE1-CB 3.48Å; E443-T458 WeakPolarHBondContact OE1-CG2 3.47Å; E443-T458 PolarHBondContact OE1-OG1 3.31Å; E443-G460 WeakPolarHBondContact CA-O 3.39Å; E443-E461 HydrophobicContact CG-CG 4.18Å
444A96.1Very high89.4Confident0 Ų059.2 Ų59.20%028%0.278CS..EExtended strand (participates in β ladder)trans-92.1135.2173.700000110.4S403 L404 I459 G460 F462 F490S403-A444 WeakPolarHBondContact O-CA 3.3Å; L404-A444 HydrophobicContact CD2-CB 3.68Å; A444-I459 HydrophobicContact CB-CB 4.13Å; A444-I459 HydrophobicContact CB-CD1 4.45Å; A444-I459 PolarHBondContact O-N 3.39Å; A444-G460 PolarHBondContact N-O 3.33Å; A444-G460 PolarHBondContact O-N 2.66Å; A444-F462 HydrophobicContact CB-CE2 4.04Å; A444-F490 HydrophobicContact CB-CD1 3.88Å; A444-F490 HydrophobicContact CB-CE1 3.69Å; A444-F490 HydrophobicContact CB-CG 4.46Å; A444-F490 HydrophobicContact CB-CZ 4.09Å
445Y95.4Very high89.1Confident33 Ų3361.4 Ų61.413%0.12929%0.293CS..EExtended strand (participates in β ladder)trans-153.1161.8-178.166.4-78.3000112.8I402 S403 K405 D416 A457I402-Y445 WeakPolarHBondContact CA-O 3.48Å; S403-Y445 VanDerWaalsContact CB-CZ 3.47Å; S403-Y445 WeakPolarHBondContact CB-OH 3.38Å; S403-Y445 PolarHBondContact N-O 3.21Å; S403-Y445 PolarHBondContact O-N 3.44Å; S403-Y445 VanDerWaalsContact O-N 3.15Å; K405-Y445 HydrophobicContact CB-CE1 3.73Å; K405-Y445 HydrophobicContact CD-CD1 3.96Å; K405-Y445 HydrophobicContact CD-CE1 3.72Å; K405-Y445 HydrophobicContact CG-CD1 3.97Å; K405-Y445 HydrophobicContact CG-CE1 3.61Å; D416-Y445 VanDerWaalsContact CB-OH 3.23Å; D416-Y445 WeakPolarHBondContact CB-OH 3.45Å; D416-Y445 PolarHBondContact OD2-OH 3.06Å; Y445-A457 CarbonylContact C-O 3.52Å; Y445-A457 WeakPolarHBondContact CA-O 3.34Å; Y445-A457 WeakPolarHBondContact CB-O 3.47Å
446Y95.1Very high88.9Confident20 Ų2059.4 Ų59.48%0.07829%0.287CS..EExtended strand (participates in β ladder)trans-84132.9174.4-62.7-61000112.4T149 D150 Y400 S401 I402 L452 A457 I459T149-Y446 HydrophobicContact CG2-CE2 4.28Å; D150-Y446 WeakPolarHBondContact CB-OH 3.38Å; D150-Y446 PolarHBondContact N-OH 3.34Å; Y400-Y446 VanDerWaalsContact CB-CD1 3.5Å; Y400-Y446 HydrophobicContact CD2-CE1 4.1Å; Y400-Y446 HydrophobicContact CG-CD1 4.25Å; Y400-Y446 HydrophobicContact CG-CE1 4.22Å; S401-Y446 WeakPolarHBondContact O-CA 3.26Å; I402-Y446 HydrophobicContact CD1-CE1 4.39Å; I402-Y446 HydrophobicContact CG1-CD1 4.07Å; I402-Y446 HydrophobicContact CG1-CE1 4.01Å; Y446-L452 HydrophobicContact CD2-CD1 3.65Å; Y446-L452 HydrophobicContact CD2-CD2 3.68Å; Y446-L452 HydrophobicContact CD2-CG 4.33Å; Y446-L452 HydrophobicContact CE2-CD1 3.94Å; Y446-L452 HydrophobicContact CG-CD1 4.1Å; Y446-L452 HydrophobicContact CG-CD2 4.23Å; Y446-A457 WeakPolarHBondContact CD2-O 3.37Å; Y446-A457 PolarHBondContact N-O 2.64Å; Y446-I459 HydrophobicContact CD1-CD1 4.08Å; Y446-I459 HydrophobicContact CD2-CG1 4.13Å; Y446-I459 HydrophobicContact CE1-CD1 3.75Å; Y446-I459 HydrophobicContact CE1-CG1 4.19Å; Y446-I459 HydrophobicContact CE2-CD1 4.22Å; Y446-I459 HydrophobicContact CE2-CG1 3.73Å; Y446-I459 HydrophobicContact CG-CD1 4.45Å
447N87.9Confident89Confident55 Ų5559.4 Ų59.429%0.29429%0.292SS..SBendtrans-77.2-29.6-170.4-65.8-7.9000114S401 S403 E418S401-N447 PolarHBondContact O-N 3.37Å; S403-N447 WeakPolarHBondContact CB-OD1 3.44Å; S403-N447 PolarHBondContact N-OD1 3.38Å; S403-N447 VanDerWaalsContact N-OD1 3.16Å; S403-N447 VanDerWaalsContact OG-CG 3.29Å; S403-N447 PolarHBondContact OG-ND2 2.79Å; S403-N447 PolarHBondContact OG-OD1 3.41Å; E418-N447 WeakPolarHBondContact CG-ND2 3.46Å; E418-N447 PolarHBondContact OE1-ND2 3.28Å
448N85.7Confident89.3Confident55 Ų5555.6 Ų55.629%0.29428%0.278SS..  trans-119.691.5-176-167.3-1.5000112.8K450 E451 L452N448-K450 PolarHBondContact O-N 3.41Å; N448-K450 VanDerWaalsContact O-N 3.08Å; N448-K450 WeakPolarHBondContact OD1-CB 3.09Å; N448-K450 PolarHBondContact OD1-N 3.07Å; N448-E451 HydrophobicContact CB-CB 4.48Å; N448-E451 WeakPolarHBondContact ND2-CG 3.43Å; N448-E451 PolarHBondContact ND2-OE1 2.85Å; N448-E451 PolarHBondContact O-N 2.67Å; N448-E451 VanDerWaalsContact O-N 3.14Å; N448-L452 PolarHBondContact O-N 2.86Å
449M83.3Confident89.5Confident99 Ų9949.4 Ų49.449%0.48825%0.249SC..THydrogen-bonded Turntrans-58.8-15173-77.3-71.4-72.500114.5L452 A457M449-L452 HydrophobicContact SD-CD2 3.88Å; M449-A457 HydrophobicContact CG-CB 4.17Å; M449-A457 HydrophobicContact SD-CB 3.64Å; M449-A457 PolarHBondContact SD-N 3.02Å
450K82.7Confident89.7Confident197 Ų19746.2 Ų46.286%0.85723%0.229SC*.THydrogen-bonded Turntrans-83.5-22.1176.9-61-178.7178.5178.50113.6N448N448-K450 PolarHBondContact O-N 3.41Å; N448-K450 VanDerWaalsContact O-N 3.08Å; N448-K450 WeakPolarHBondContact OD1-CB 3.09Å; N448-K450 PolarHBondContact OD1-N 3.07Å
451E80.7Confident89.8Confident81 Ų8147.6 Ų47.638%0.37924%0.235SC..THydrogen-bonded Turntrans-96.6-12.4175.8-72.4177.4-128.200112.3Y400 K422 N448Y400-E451 WeakPolarHBondContact CE1-O 3.41Å; K422-E451 WeakPolarHBondContact CD-OE2 3.32Å; K422-E451 IonicContact NZ-OE2 2.67Å; K422-E451 PolarHBondContact NZ-OE2 3.21Å; N448-E451 HydrophobicContact CB-CB 4.48Å; N448-E451 WeakPolarHBondContact ND2-CG 3.43Å; N448-E451 PolarHBondContact ND2-OE1 2.85Å; N448-E451 PolarHBondContact O-N 2.67Å; N448-E451 VanDerWaalsContact O-N 3.14Å
452L85.3Confident89.9Confident11 Ų1143.5 Ų43.56%0.05822%0.215CC..  trans-92108.3-177-17772.2000110.5T149 Y400 Y446 N448 M449 Y454 K456T149-L452 HydrophobicContact CG2-CD1 3.7Å; Y400-L452 HydrophobicContact CD1-CD1 4.4Å; Y400-L452 HydrophobicContact CD2-CD1 4.36Å; Y400-L452 HydrophobicContact CE1-CD1 4.29Å; Y400-L452 HydrophobicContact CE2-CD1 4.25Å; Y400-L452 HydrophobicContact CG-CD1 4.44Å; Y446-L452 HydrophobicContact CD2-CD1 3.65Å; Y446-L452 HydrophobicContact CD2-CD2 3.68Å; Y446-L452 HydrophobicContact CD2-CG 4.33Å; Y446-L452 HydrophobicContact CE2-CD1 3.94Å; Y446-L452 HydrophobicContact CG-CD1 4.1Å; Y446-L452 HydrophobicContact CG-CD2 4.23Å; N448-L452 PolarHBondContact O-N 2.86Å; M449-L452 HydrophobicContact SD-CD2 3.88Å; L452-Y454 PolarHBondContact O-N 3.1Å; L452-K456 WeakPolarHBondContact CD2-O 3.34Å
453N83.6Confident90Very high57 Ų5746.1 Ų46.131%0.30523%0.229SC..  trans-81.350175.6-161.319.5000112.5R73 I79 S229 D230R73-N453 PolarHBondContact NH1-O 2.78Å; R73-N453 VanDerWaalsContact NH1-O 3.1Å; R73-N453 PolarHBondContact NH2-O 2.93Å; I79-N453 WeakPolarHBondContact CD1-OD1 3.23Å; S229-N453 PolarHBondContact OG-ND2 3.47Å; D230-N453 PolarHBondContact OD2-ND2 2.94Å
454Y86Confident89.9Confident13 Ų1344.5 Ų44.55%0.05122%0.221CC..SBendtrans-151135.3-172.9-169.9-85.2000110.1G72 R73 T149 L452 K456 W586G72-Y454 WeakPolarHBondContact O-CE2 3.34Å; G72-Y454 PolarHBondContact O-OH 2.8Å; R73-Y454 HydrophobicContact CG-CD2 4.2Å; R73-Y454 HydrophobicContact CG-CE2 3.67Å; T149-Y454 HydrophobicContact CG2-CD2 4.3Å; T149-Y454 HydrophobicContact CG2-CG 4.17Å; L452-Y454 PolarHBondContact O-N 3.1Å; Y454-K456 VanDerWaalsContact C-N 3.28Å; Y454-K456 WeakPolarHBondContact CD1-O 3.5Å; Y454-K456 HydrophobicContact CE1-CB 4.25Å; Y454-K456 PolarHBondContact O-N 3.05Å; Y454-K456 VanDerWaalsContact O-N 3.1Å; Y454-W586 PolarHBondContact OH-NE1 2.85Å
455P84.7Confident89.8Confident59 Ų5947.3 Ų47.338%0.38323%0.234SC..SBendtrans-73.4-4.8-16327.7-37.3000116.6D77D77-P455 HydrophobicContact CB-CG 4.23Å; D77-P455 VanDerWaalsContact OD2-CD 3.31Å; D77-P455 WeakPolarHBondContact OD2-CD 3.26Å
456K86.3Confident89.6Confident84 Ų8450.7 Ų50.737%0.36525%0.254SS..  trans-133.7134.9178.9-68.6179.1173.7177.30111.2L452 Y454L452-K456 WeakPolarHBondContact CD2-O 3.34Å; Y454-K456 VanDerWaalsContact C-N 3.28Å; Y454-K456 WeakPolarHBondContact CD1-O 3.5Å; Y454-K456 HydrophobicContact CE1-CB 4.25Å; Y454-K456 PolarHBondContact O-N 3.05Å; Y454-K456 VanDerWaalsContact O-N 3.1Å
457A91.6Very high89.2Confident23 Ų2349.9 Ų49.919%0.1925%0.252CS..  trans-70.4-34.3171.300000113Y445 Y446 M449 I459Y445-A457 CarbonylContact C-O 3.52Å; Y445-A457 WeakPolarHBondContact CA-O 3.34Å; Y445-A457 WeakPolarHBondContact CB-O 3.47Å; Y446-A457 WeakPolarHBondContact CD2-O 3.37Å; Y446-A457 PolarHBondContact N-O 2.64Å; M449-A457 HydrophobicContact CG-CB 4.17Å; M449-A457 HydrophobicContact SD-CB 3.64Å; M449-A457 PolarHBondContact SD-N 3.02Å; A457-I459 PolarHBondContact O-N 2.99Å
458T93.8Very high89.2Confident33 Ų3351.1 Ų51.120%0.20226%0.261CS..EExtended strand (participates in β ladder)trans-65.2129.6-172.7-53.50000111.9E443 Q585E443-T458 HydrophobicContact CG-CG2 3.74Å; E443-T458 WeakPolarHBondContact OE1-CB 3.48Å; E443-T458 WeakPolarHBondContact OE1-CG2 3.47Å; E443-T458 PolarHBondContact OE1-OG1 3.31Å; T458-Q585 HydrophobicContact CG2-CG 4.32Å; T458-Q585 VanDerWaalsContact O-CG 3.31Å; T458-Q585 WeakPolarHBondContact O-CG 3.44Å
459I95.1Very high89.2Confident5 Ų551.4 Ų51.43%0.02627%0.266CS..EExtended strand (participates in β ladder)trans-90.9-47.4172.6-63.5163.7000109.5D150 I402 A444 Y446 A457 F490 L584 Q585D150-I459 HydrophobicContact CB-CG1 4.43Å; D150-I459 HydrophobicContact CB-CG2 3.78Å; D150-I459 VanDerWaalsContact CG-CG2 3.44Å; D150-I459 WeakPolarHBondContact OD1-CG2 3.38Å; I402-I459 HydrophobicContact CD1-CD1 4.11Å; I402-I459 HydrophobicContact CG1-CD1 4.04Å; I402-I459 HydrophobicContact CG2-CD1 3.82Å; A444-I459 HydrophobicContact CB-CB 4.13Å; A444-I459 HydrophobicContact CB-CD1 4.45Å; A444-I459 PolarHBondContact O-N 3.39Å; Y446-I459 HydrophobicContact CD1-CD1 4.08Å; Y446-I459 HydrophobicContact CD2-CG1 4.13Å; Y446-I459 HydrophobicContact CE1-CD1 3.75Å; Y446-I459 HydrophobicContact CE1-CG1 4.19Å; Y446-I459 HydrophobicContact CE2-CD1 4.22Å; Y446-I459 HydrophobicContact CE2-CG1 3.73Å; Y446-I459 HydrophobicContact CG-CD1 4.45Å; A457-I459 PolarHBondContact O-N 2.99Å; I459-F490 HydrophobicContact CG2-CB 4.31Å; I459-L584 HydrophobicContact CG2-CD2 4.33Å; I459-Q585 PolarHBondContact O-N 3.01Å
460G94.5Very high89.1Confident0 Ų050.5 Ų50.50%026%0.257CS..EExtended strand (participates in β ladder)trans178.6160.2178.100000114.3E443 A444 K583E443-G460 WeakPolarHBondContact CA-O 3.39Å; A444-G460 PolarHBondContact N-O 3.33Å; A444-G460 PolarHBondContact O-N 2.66Å; G460-K583 CarbonylContact C-O 3.6Å; G460-K583 VanDerWaalsContact CA-O 3.23Å; G460-K583 WeakPolarHBondContact CA-O 3.49Å
461E95.2Very high88.9Confident43 Ų4347 Ų4720%0.20126%0.264CS..EExtended strand (participates in β ladder)trans-98.3138.7174.8-64.9151.3-147.400108.9M441 E443 K583M441-E461 HydrophobicContact CG-CB 4.46Å; M441-E461 HydrophobicContact SD-CB 4.07Å; M441-E461 HydrophobicContact SD-CG 4.06Å; E443-E461 HydrophobicContact CG-CG 4.18Å; E461-K583 HydrophobicContact CB-CB 4.4Å; E461-K583 PolarHBondContact N-O 3.36Å; E461-K583 PolarHBondContact O-N 3.12Å; E461-K583 IonicContact OE1-NZ 2.75Å; E461-K583 PolarHBondContact OE1-NZ 3.2Å; E461-K583 WeakPolarHBondContact OE2-CD 3.32Å; E461-K583 IonicContact OE2-NZ 2.69Å; E461-K583 PolarHBondContact OE2-NZ 2.72Å
462F95.9Very high88.7Confident11 Ų1146.8 Ų46.85%0.04827%0.272CS..EExtended strand (participates in β ladder)trans-132.4115.2178.6-57.5-90.6000109.7M441 L442 A444 F490 V492 I580 E581 L584M441-F462 CarbonylContact C-O 3.52Å; M441-F462 WeakPolarHBondContact CA-O 3.39Å; L442-F462 PolarHBondContact N-O 2.97Å; L442-F462 PolarHBondContact O-N 2.73Å; A444-F462 HydrophobicContact CB-CE2 4.04Å; F462-F490 HydrophobicContact CD2-CE1 4.37Å; F462-F490 AromaticContact CE2-CD1 3.92Å; F462-F490 HydrophobicContact CE2-CD1 3.92Å; F462-F490 AromaticContact CE2-CE1 3.62Å; F462-F490 HydrophobicContact CE2-CE1 3.62Å; F462-F490 AromaticContact CZ-CD1 3.9Å; F462-F490 HydrophobicContact CZ-CD1 3.9Å; F462-F490 AromaticContact CZ-CE1 3.91Å; F462-F490 HydrophobicContact CZ-CE1 3.91Å; F462-V492 HydrophobicContact CB-CG2 3.83Å; F462-V492 HydrophobicContact CD1-CB 4.04Å; F462-V492 HydrophobicContact CD1-CG2 3.57Å; F462-V492 HydrophobicContact CD2-CG2 3.74Å; F462-V492 HydrophobicContact CE1-CB 4.45Å; F462-V492 HydrophobicContact CE1-CG2 4.01Å; F462-V492 HydrophobicContact CE2-CG2 4.17Å; F462-V492 HydrophobicContact CG-CB 4.32Å; F462-V492 HydrophobicContact CG-CG2 3.42Å; F462-V492 VanDerWaalsContact CG-CG2 3.42Å; F462-V492 HydrophobicContact CZ-CG2 4.29Å; F462-I580 HydrophobicContact CB-CG2 4.32Å; F462-I580 HydrophobicContact CD1-CG2 4.29Å; F462-E581 CarbonylContact C-O 3.58Å; F462-E581 WeakPolarHBondContact CA-O 3.45Å; F462-L584 HydrophobicContact CE1-CD2 4.5Å; F462-L584 HydrophobicContact CZ-CD2 3.9Å
463L94.9Very high88.3Confident55 Ų5548.1 Ų48.129%0.28829%0.289SS..EExtended strand (participates in β ladder)trans-92.5118.7175.6174.462.1000109.5P439 Q465 I580 E581P439-L463 HydrophobicContact CB-CD1 4.25Å; L463-Q465 HydrophobicContact CD2-CG 4.17Å; L463-Q465 HydrophobicContact CG-CG 4.02Å; L463-I580 WeakPolarHBondContact O-CA 3.48Å; L463-E581 HydrophobicContact CB-CB 4.33Å; L463-E581 PolarHBondContact N-O 3.47Å; L463-E581 PolarHBondContact O-N 3.12Å
464I94.5Very high88.3Confident0 Ų050.4 Ų50.40%030%0.298CS..EExtended strand (participates in β ladder)trans-89.7106.2172.9-61.578.3000107.1P439 F440 L442 V467 V480 A495 L578P439-I464 VanDerWaalsContact CA-O 3.31Å; P439-I464 WeakPolarHBondContact CA-O 3.45Å; P439-I464 WeakPolarHBondContact CB-O 3.28Å; F440-I464 HydrophobicContact CD1-CB 4.18Å; F440-I464 HydrophobicContact CE1-CB 3.85Å; F440-I464 HydrophobicContact CE1-CD1 4.41Å; F440-I464 HydrophobicContact CE1-CG1 4.24Å; F440-I464 HydrophobicContact CE1-CG2 4.1Å; F440-I464 HydrophobicContact CE2-CD1 4.23Å; F440-I464 HydrophobicContact CZ-CB 4.36Å; F440-I464 HydrophobicContact CZ-CD1 4.12Å; F440-I464 HydrophobicContact CZ-CG1 4.24Å; F440-I464 PolarHBondContact N-O 3.33Å; F440-I464 PolarHBondContact O-N 3.19Å; L442-I464 HydrophobicContact CB-CD1 4.37Å; L442-I464 HydrophobicContact CD1-CD1 3.83Å; L442-I464 HydrophobicContact CG-CD1 3.74Å; I464-V467 HydrophobicContact CG2-CG2 3.84Å; I464-V480 HydrophobicContact CG1-CG2 4.42Å; I464-A495 HydrophobicContact CG1-CB 4.16Å; I464-A495 HydrophobicContact CG2-CB 3.78Å; I464-L578 HydrophobicContact CG2-CB 4.04Å; I464-L578 HydrophobicContact CG2-CD1 3.67Å
465Q92.9Very high88.3Confident59 Ų5951.7 Ų51.728%0.27631%0.308SS..  trans-83.6171.3-175.5-60.1-177.8-7.200111.9L463 V467 P579 E581L463-Q465 HydrophobicContact CD2-CG 4.17Å; L463-Q465 HydrophobicContact CG-CG 4.02Å; Q465-V467 PolarHBondContact O-N 2.72Å; Q465-P579 HydrophobicContact CB-CB 4.19Å; Q465-P579 PolarHBondContact N-O 2.82Å; Q465-E581 PolarHBondContact NE2-OE2 3.28Å
466N91.6Very high88.4Confident104 Ų10449 Ų4956%0.55629%0.291SS*.  trans54.520.3172.5-59.3-12.6000116.3V468 L578N466-V468 PolarHBondContact O-N 3.42Å; N466-L578 HydrophobicContact CB-CD2 4.4Å
467V88Confident88.7Confident4 Ų448 Ų482%0.02429%0.287CS..  trans-70.5115.1169.11790000108.8R436 E438 P439 F440 I464 Q465 V478 L578R436-V467 HydrophobicContact CB-CG1 3.66Å; E438-V467 CarbonylContact C-O 3.52Å; E438-V467 WeakPolarHBondContact CA-O 3.26Å; E438-V467 WeakPolarHBondContact O-CB 3.3Å; E438-V467 WeakPolarHBondContact O-CG1 3.42Å; P439-V467 WeakPolarHBondContact CD-O 3.24Å; F440-V467 HydrophobicContact CD1-CG2 4.16Å; F440-V467 HydrophobicContact CE1-CG2 4.13Å; I464-V467 HydrophobicContact CG2-CG2 3.84Å; Q465-V467 PolarHBondContact O-N 2.72Å; V467-V478 HydrophobicContact CG1-CG2 3.97Å; V467-V478 HydrophobicContact CG2-CG2 4.13Å; V467-L578 HydrophobicContact CG2-CD1 3.69Å
468V86.8Confident88.7Confident81 Ų8147 Ų4749%0.49128%0.278SS..  trans-112.7153.5176.3-67.70000110.4K437 N466 S476 L497K437-V468 CarbonylContact O-C 3.54Å; N466-V468 PolarHBondContact O-N 3.42Å; V468-S476 WeakPolarHBondContact O-CB 3.29Å; V468-S476 PolarHBondContact O-OG 3.33Å; V468-L497 HydrophobicContact CG2-CD1 4.11Å
469P85Confident88.7Confident60 Ų6049.9 Ų49.939%0.3929%0.288SS..  trans-69.5166.2173.233-34.7000110.3K437 E474K437-P469 HydrophobicContact CB-CB 4.28Å; K437-P469 HydrophobicContact CG-CB 4.4Å; K437-P469 VanDerWaalsContact O-CD 3.22Å; K437-P469 WeakPolarHBondContact O-CD 3Å; P469-E474 WeakPolarHBondContact CB-O 3.4Å
470R82.7Confident88.8Confident80 Ų8049.6 Ų49.630%0.30229%0.286SS..  trans-66.6162.5171-69.5176.4165.3171.9-3.1110.7S472 G473 E474 S476R470-S472 WeakPolarHBondContact CB-OG 3.46Å; R470-S472 PolarHBondContact O-N 2.86Å; R470-G473 PolarHBondContact O-N 3.25Å; R470-E474 HydrophobicContact CB-CB 4.48Å; R470-E474 PolarHBondContact N-O 3.47Å; R470-E474 IonicContact NH1-OE2 3.8Å; R470-S476 PolarHBondContact N-OG 3.05Å
471A77.6Confident88.9Confident123 Ų12353.8 Ų53.8100%1.01730%0.304SS*.THydrogen-bonded Turntrans-56.1-16.6170.400000114.2
472S76.8Confident89Confident77 Ų7751.7 Ų51.754%0.53830%0.295SS..THydrogen-bonded Turntrans-83.9-2.1171.549.90000115R470 E474R470-S472 WeakPolarHBondContact CB-OG 3.46Å; R470-S472 PolarHBondContact O-N 2.86Å; S472-E474 PolarHBondContact O-N 2.69Å; S472-E474 WeakPolarHBondContact OG-CB 3.39Å; S472-E474 WeakPolarHBondContact OG-CG 3.36Å; S472-E474 PolarHBondContact OG-OE2 3.22Å
473G77.1Confident89Confident40 Ų4055.6 Ų55.641%0.41231%0.309SS..SBendtrans74.60.8-170.300000114.6K437 R470K437-G473 WeakPolarHBondContact CE-O 3.28Å; K437-G473 PolarHBondContact NZ-O 2.92Å; R470-G473 PolarHBondContact O-N 3.25Å
474E83.4Confident89.1Confident105 Ų10553 Ų5349%0.49130%0.296SS..SBendtrans-78.2160.9176.6-64.1175.6139.200112.5P469 R470 S472 S476P469-E474 WeakPolarHBondContact CB-O 3.4Å; R470-E474 HydrophobicContact CB-CB 4.48Å; R470-E474 PolarHBondContact N-O 3.47Å; R470-E474 IonicContact NH1-OE2 3.8Å; S472-E474 PolarHBondContact O-N 2.69Å; S472-E474 WeakPolarHBondContact OG-CB 3.39Å; S472-E474 WeakPolarHBondContact OG-CG 3.36Å; S472-E474 PolarHBondContact OG-OE2 3.22Å; E474-S476 PolarHBondContact O-N 3.32Å
475S85.2Confident89.1Confident39 Ų3954.6 Ų54.627%0.27330%0.304SS..PPolyproline II helixtrans-61123.5173-59.70000112.2R436R436-S475 CarbonylContact O-C 3.56Å; R436-S475 WeakPolarHBondContact O-CA 3.5Å
476S87.9Confident89.2Confident3 Ų354.4 Ų54.42%0.02131%0.307CS..EExtended strand (participates in β ladder)trans-68.9146.4170.5-76.40000111.7Y435 R436 V468 R470 E474 V478Y435-S476 CarbonylContact C-O 3.58Å; Y435-S476 WeakPolarHBondContact CA-O 3.35Å; R436-S476 PolarHBondContact N-O 3.29Å; R436-S476 PolarHBondContact O-N 3.41Å; V468-S476 WeakPolarHBondContact O-CB 3.29Å; V468-S476 PolarHBondContact O-OG 3.33Å; R470-S476 PolarHBondContact N-OG 3.05Å; E474-S476 PolarHBondContact O-N 3.32Å; S476-V478 PolarHBondContact O-N 2.94Å
477K91.3Very high89.4Confident64 Ų6450.6 Ų50.628%0.27829%0.286SS..EExtended strand (participates in β ladder)trans-88.7106.8179.6-177.2174.4-171.4163.70109.4T433 Y435 V498T433-K477 HydrophobicContact CG2-CD 4.34Å; T433-K477 VanDerWaalsContact CG2-CE 3.46Å; T433-K477 HydrophobicContact CG2-CG 3.93Å; Y435-K477 HydrophobicContact CD1-CB 4.04Å; Y435-K477 HydrophobicContact CD1-CG 4.27Å; Y435-K477 HydrophobicContact CE1-CB 3.74Å; Y435-K477 HydrophobicContact CE1-CD 3.86Å; Y435-K477 HydrophobicContact CE1-CG 3.64Å; Y435-K477 WeakPolarHBondContact OH-CE 3.49Å; Y435-K477 PolarHBondContact OH-NZ 2.71Å; K477-V498 HydrophobicContact CB-CB 4.33Å; K477-V498 PolarHBondContact O-N 2.95Å
478V92.6Very high89.7Confident0 Ų051.6 Ų51.60%030%0.297CS..EExtended strand (participates in β ladder)trans-101.2122.5179.1-175.30000109.3T433 F434 R436 F440 V467 S476 V480 A496 L578T433-V478 WeakPolarHBondContact CA-O 3.44Å; F434-V478 PolarHBondContact N-O 3.07Å; F434-V478 PolarHBondContact O-N 3.48Å; R436-V478 HydrophobicContact CB-CG2 4.5Å; F440-V478 HydrophobicContact CE1-CG1 4.35Å; V467-V478 HydrophobicContact CG1-CG2 3.97Å; V467-V478 HydrophobicContact CG2-CG2 4.13Å; S476-V478 PolarHBondContact O-N 2.94Å; V478-V480 HydrophobicContact CG1-CG2 3.94Å; V478-A496 WeakPolarHBondContact CA-O 3.09Å; V478-L578 HydrophobicContact CG1-CD1 3.74Å; V478-L578 HydrophobicContact CG2-CD1 4.28Å
479K94.6Very high90.2Very high94 Ų9447.8 Ų47.841%0.40927%0.274SS..EExtended strand (participates in β ladder)trans-92.4129.3168.5-69.9175.6178172.90108.6V431 L432 A495 A496 V498V431-K479 HydrophobicContact CG1-CB 4.19Å; V431-K479 HydrophobicContact CG1-CG 4.48Å; L432-K479 WeakPolarHBondContact O-CA 3.37Å; K479-A495 CarbonylContact O-C 3.46Å; K479-A495 WeakPolarHBondContact O-CA 3.43Å; K479-A496 PolarHBondContact N-O 3.37Å; K479-A496 PolarHBondContact O-N 3.5Å; K479-V498 HydrophobicContact CD-CG2 3.92Å; K479-V498 HydrophobicContact CG-CG2 4.03Å
480V96.1Very high90.7Very high0 Ų045 Ų450%026%0.256CS..EExtended strand (participates in β ladder)trans-122.7124.5175.5-175.90000109V431 L432 F434 F440 L442 I464 V478 V482 V492 A495V431-V480 WeakPolarHBondContact CA-O 3.3Å; L432-V480 PolarHBondContact N-O 2.86Å; L432-V480 PolarHBondContact O-N 3.15Å; F434-V480 HydrophobicContact CD2-CB 4.29Å; F434-V480 HydrophobicContact CD2-CG2 3.74Å; F434-V480 HydrophobicContact CE2-CB 3.96Å; F434-V480 HydrophobicContact CE2-CG2 3.83Å; F440-V480 HydrophobicContact CZ-CG2 4.29Å; L442-V480 HydrophobicContact CD1-CG1 4.03Å; I464-V480 HydrophobicContact CG1-CG2 4.42Å; V478-V480 HydrophobicContact CG1-CG2 3.94Å; V480-V482 HydrophobicContact CG1-CG1 4.02Å; V480-V492 HydrophobicContact CG1-CG1 3.41Å; V480-V492 VanDerWaalsContact CG1-CG1 3.41Å; V480-A495 HydrophobicContact CG2-CB 4.1Å
481K96.6Very high91.3Very high87 Ų8742.7 Ų42.738%0.37825%0.251SS..EExtended strand (participates in β ladder)trans-101.7104.6-178.1-176-173.7174.7-175.50109.8V431 S493 S494V431-K481 HydrophobicContact CG2-CB 4.19Å; V431-K481 HydrophobicContact CG2-CG 4.05Å; K481-S493 WeakPolarHBondContact CD-OG 3.42Å; K481-S493 WeakPolarHBondContact CG-OG 3.39Å; K481-S493 PolarHBondContact O-N 3.12Å; K481-S493 PolarHBondContact O-OG 3.34Å; K481-S494 PolarHBondContact N-O 3.44Å
482V96.9Very high92.1Very high0 Ų037.6 Ų37.60%021%0.208CC..EExtended strand (participates in β ladder)trans-101.2143.3-179.8-61.80000110.8L404 V419 F420 S429 K430 L432 V480 F490 S491 V492L404-V482 HydrophobicContact CD1-CB 4.45Å; L404-V482 HydrophobicContact CD1-CG1 3.89Å; L404-V482 HydrophobicContact CD1-CG2 4.2Å; V419-V482 HydrophobicContact CG1-CG2 3.47Å; V419-V482 VanDerWaalsContact CG1-CG2 3.47Å; F420-V482 HydrophobicContact CE2-CG2 4.49Å; S429-V482 CarbonylContact C-O 3.15Å; S429-V482 VanDerWaalsContact CA-O 3.3Å; S429-V482 WeakPolarHBondContact CA-O 3.46Å; K430-V482 HydrophobicContact CB-CG2 4.26Å; K430-V482 PolarHBondContact N-O 3.42Å; K430-V482 WeakPolarHBondContact O-CG2 3.47Å; K430-V482 PolarHBondContact O-N 3.09Å; L432-V482 HydrophobicContact CD1-CG2 4.29Å; L432-V482 HydrophobicContact CG-CG2 4.45Å; V480-V482 HydrophobicContact CG1-CG1 4.02Å; V482-F490 HydrophobicContact CB-CE2 4.08Å; V482-F490 HydrophobicContact CB-CZ 3.85Å; V482-F490 HydrophobicContact CG1-CZ 4.03Å; V482-S491 CarbonylContact C-O 3.59Å; V482-S491 WeakPolarHBondContact CA-O 3.33Å; V482-V492 HydrophobicContact CG1-CG1 4.33Å; V482-V492 HydrophobicContact CG1-CG2 4.09Å
483R96.6Very high92.9Very high93 Ų9336.4 Ų36.435%0.35120%0.2SC..EExtended strand (participates in β ladder)trans-143.8134.3-166.7175.4173.2-167.1-1715.2112.1F428 S429 F490 S491F428-R483 WeakPolarHBondContact O-CA 3.31Å; F428-R483 WeakPolarHBondContact O-CG 3.46Å; S429-R483 WeakPolarHBondContact OG-CD 3.45Å; S429-R483 WeakPolarHBondContact OG-CG 3.48Å; R483-F490 CarbonylContact O-C 3.54Å; R483-F490 WeakPolarHBondContact O-CA 3.21Å; R483-S491 PolarHBondContact N-O 3.47Å; R483-S491 PolarHBondContact O-N 2.93Å; R483-S491 PolarHBondContact O-OG 2.96Å
484V96.8Very high93.7Very high1 Ų136.6 Ų36.61%0.00620%0.195CC..EExtended strand (participates in β ladder)trans-89.8123.6153.21800000107.7V398 I402 F420 A426 P427 F428 V489V398-V484 HydrophobicContact CG2-CB 4.43Å; V398-V484 HydrophobicContact CG2-CG1 4.22Å; V398-V484 HydrophobicContact CG2-CG2 4.17Å; I402-V484 HydrophobicContact CD1-CG2 4.27Å; F420-V484 HydrophobicContact CD1-CG2 4.14Å; F420-V484 HydrophobicContact CD2-CG2 3.79Å; F420-V484 HydrophobicContact CE1-CG2 4.15Å; F420-V484 HydrophobicContact CE2-CG2 3.81Å; F420-V484 HydrophobicContact CG-CG2 3.96Å; F420-V484 HydrophobicContact CZ-CG2 4.01Å; A426-V484 HydrophobicContact CB-CG1 4.28Å; P427-V484 WeakPolarHBondContact CA-O 3.48Å; P427-V484 WeakPolarHBondContact CB-O 3.46Å; F428-V484 PolarHBondContact N-O 3.13Å; F428-V484 VanDerWaalsContact N-O 3.07Å; F428-V484 PolarHBondContact O-N 3.48Å; V484-V489 WeakPolarHBondContact CA-O 3.4Å
485N95Very high94.2Very high32 Ų3231.7 Ų31.717%0.17117%0.172CC..  trans-91-172.6-172.976.612.9000112.6H487 G488 V489N485-H487 PolarHBondContact O-N 3.05Å; N485-H487 WeakPolarHBondContact OD1-CB 3.44Å; N485-H487 PolarHBondContact OD1-CD2 2.99Å; N485-H487 PolarHBondContact OD1-N 2.92Å; N485-G488 PolarHBondContact O-N 3.16Å; N485-G488 VanDerWaalsContact O-N 3.15Å; N485-G488 PolarHBondContact OD1-N 2.9Å; N485-V489 PolarHBondContact N-O 2.91Å; N485-V489 WeakPolarHBondContact ND2-CG2 3.4Å; N485-V489 WeakPolarHBondContact OD1-CG2 3.37Å; N485-V489 PolarHBondContact OD1-N 3.08Å; N485-V489 PolarHBondContact OD1-O 3.25Å
486V94.4Very high94.7Very high55 Ų5530.4 Ų30.433%0.33316%0.164SC..THydrogen-bonded Turntrans-67.1-19.4-175.6-63.70000114.5R169 P427R169-V486 WeakPolarHBondContact CG-O 3.38Å; R169-V486 PolarHBondContact NE-O 2.66Å; P427-V486 HydrophobicContact CB-CG1 4.36Å; P427-V486 HydrophobicContact CG-CG1 4.11Å
487H96.3Very high94.8Very high24 Ų2430.5 Ų30.511%0.11116%0.164CC..THydrogen-bonded Turntrans-88.4-7.8177.6-46.1-99.4000112.2R153 M157 C167 L170 N485 V489R153-H487 WeakPolarHBondContact CD-O 3.38Å; R153-H487 PolarHBondContact NH1-O 3.37Å; M157-H487 HydrophobicContact SD-CB 4.01Å; C167-H487 PolarHBondContact O-CE1 2.61Å; L170-H487 HydrophobicContact CB-CB 3.97Å; L170-H487 HydrophobicContact CD1-CB 4.4Å; L170-H487 HydrophobicContact CG-CB 4.2Å; L170-H487 PolarHBondContact N-ND1 3.12Å; N485-H487 PolarHBondContact O-N 3.05Å; N485-H487 WeakPolarHBondContact OD1-CB 3.44Å; N485-H487 PolarHBondContact OD1-CD2 2.99Å; N485-H487 PolarHBondContact OD1-N 2.92Å; H487-V489 HydrophobicContact CB-CG2 4.48Å
488G95Very high94.6Very high25 Ų2528 Ų2826%0.25815%0.154SC..SBendtrans86.38.6-173.500000114.9N485N485-G488 PolarHBondContact O-N 3.16Å; N485-G488 VanDerWaalsContact O-N 3.15Å; N485-G488 PolarHBondContact OD1-N 2.9Å
489V95.9Very high94Very high2 Ų231.2 Ų31.21%0.01217%0.169CC..  trans-95.1147.4179.1-57.90000112.7D150 R153 V484 N485 H487D150-V489 VanDerWaalsContact OD2-CA 3.24Å; D150-V489 WeakPolarHBondContact OD2-CA 3.39Å; D150-V489 VanDerWaalsContact OD2-CB 3.24Å; D150-V489 WeakPolarHBondContact OD2-CB 3.47Å; R153-V489 HydrophobicContact CB-CG1 3.47Å; R153-V489 VanDerWaalsContact CB-CG1 3.47Å; R153-V489 HydrophobicContact CG-CG1 4.36Å; V484-V489 WeakPolarHBondContact CA-O 3.4Å; N485-V489 PolarHBondContact N-O 2.91Å; N485-V489 WeakPolarHBondContact ND2-CG2 3.4Å; N485-V489 WeakPolarHBondContact OD1-CG2 3.37Å; N485-V489 PolarHBondContact OD1-N 3.08Å; N485-V489 PolarHBondContact OD1-O 3.25Å; H487-V489 HydrophobicContact CB-CG2 4.48Å
490F96.4Very high93Very high1 Ų130 Ų300%0.00417%0.169CC..EExtended strand (participates in β ladder)trans-77150.8177.9-177.7-87.7000111.7D150 R154 I402 L404 F420 A444 I459 F462 V482 R483 V492D150-F490 PolarHBondContact OD2-N 3.1Å; R154-F490 PolarHBondContact NH2-O 2.73Å; I402-F490 HydrophobicContact CD1-CD2 4.45Å; I402-F490 HydrophobicContact CG2-CD2 4Å; I402-F490 HydrophobicContact CG2-CE2 4.25Å; L404-F490 HydrophobicContact CD1-CZ 4.27Å; L404-F490 HydrophobicContact CD2-CE1 4.31Å; L404-F490 HydrophobicContact CD2-CZ 3.78Å; L404-F490 HydrophobicContact CG-CZ 4.32Å; F420-F490 HydrophobicContact CD2-CD2 4.32Å; F420-F490 HydrophobicContact CD2-CE2 4.34Å; F420-F490 AromaticContact CE2-CD2 3.98Å; F420-F490 HydrophobicContact CE2-CD2 3.98Å; F420-F490 AromaticContact CE2-CE2 3.84Å; F420-F490 HydrophobicContact CE2-CE2 3.84Å; A444-F490 HydrophobicContact CB-CD1 3.88Å; A444-F490 HydrophobicContact CB-CE1 3.69Å; A444-F490 HydrophobicContact CB-CG 4.46Å; A444-F490 HydrophobicContact CB-CZ 4.09Å; I459-F490 HydrophobicContact CG2-CB 4.31Å; F462-F490 HydrophobicContact CD2-CE1 4.37Å; F462-F490 AromaticContact CE2-CD1 3.92Å; F462-F490 HydrophobicContact CE2-CD1 3.92Å; F462-F490 AromaticContact CE2-CE1 3.62Å; F462-F490 HydrophobicContact CE2-CE1 3.62Å; F462-F490 AromaticContact CZ-CD1 3.9Å; F462-F490 HydrophobicContact CZ-CD1 3.9Å; F462-F490 AromaticContact CZ-CE1 3.91Å; F462-F490 HydrophobicContact CZ-CE1 3.91Å; V482-F490 HydrophobicContact CB-CE2 4.08Å; V482-F490 HydrophobicContact CB-CZ 3.85Å; V482-F490 HydrophobicContact CG1-CZ 4.03Å; R483-F490 CarbonylContact O-C 3.54Å; R483-F490 WeakPolarHBondContact O-CA 3.21Å; F490-V492 HydrophobicContact CE1-CG2 4.1Å
491S94.8Very high91.5Very high31 Ų3133.8 Ų33.822%0.21719%0.189CC..EExtended strand (participates in β ladder)trans-158.3144.4176.652.70000111.6V482 R483V482-S491 CarbonylContact C-O 3.59Å; V482-S491 WeakPolarHBondContact CA-O 3.33Å; R483-S491 PolarHBondContact N-O 3.47Å; R483-S491 PolarHBondContact O-N 2.93Å; R483-S491 PolarHBondContact O-OG 2.96Å
492V95.5Very high89.6Confident17 Ų1738.1 Ų38.110%0.10321%0.207CC..EExtended strand (participates in β ladder)trans-88.4106.8159.5-172.80000106.8F462 V480 V482 F490 I580F462-V492 HydrophobicContact CB-CG2 3.83Å; F462-V492 HydrophobicContact CD1-CB 4.04Å; F462-V492 HydrophobicContact CD1-CG2 3.57Å; F462-V492 HydrophobicContact CD2-CG2 3.74Å; F462-V492 HydrophobicContact CE1-CB 4.45Å; F462-V492 HydrophobicContact CE1-CG2 4.01Å; F462-V492 HydrophobicContact CE2-CG2 4.17Å; F462-V492 HydrophobicContact CG-CB 4.32Å; F462-V492 HydrophobicContact CG-CG2 3.42Å; F462-V492 VanDerWaalsContact CG-CG2 3.42Å; F462-V492 HydrophobicContact CZ-CG2 4.29Å; V480-V492 HydrophobicContact CG1-CG1 3.41Å; V480-V492 VanDerWaalsContact CG1-CG1 3.41Å; V482-V492 HydrophobicContact CG1-CG1 4.33Å; V482-V492 HydrophobicContact CG1-CG2 4.09Å; F490-V492 HydrophobicContact CE1-CG2 4.1Å; V492-I580 HydrophobicContact CB-CD1 4.32Å; V492-I580 HydrophobicContact CB-CG2 4.26Å; V492-I580 HydrophobicContact CG1-CD1 3.63Å; V492-I580 HydrophobicContact CG1-CG1 4.31Å; V492-I580 HydrophobicContact CG1-CG2 4.35Å
493S92.2Very high87.1Confident52 Ų5242.8 Ų42.836%0.36423%0.233SC..EExtended strand (participates in β ladder)trans-91.6-13.4-167.6680000114.9K481K481-S493 WeakPolarHBondContact CD-OG 3.42Å; K481-S493 WeakPolarHBondContact CG-OG 3.39Å; K481-S493 PolarHBondContact O-N 3.12Å; K481-S493 PolarHBondContact O-OG 3.34Å
494S94.6Very high84.4Confident44 Ų4444.9 Ų44.931%0.30826%0.255SS..EExtended strand (participates in β ladder)trans-175.8148.6174.115.10000109.4K481K481-S494 PolarHBondContact N-O 3.44Å
495A94.5Very high81.8Confident2 Ų254.3 Ų54.32%0.01730%0.299CS..EExtended strand (participates in β ladder)trans-133134.6168.300000107.7I464 K479 V480 L578 I580I464-A495 HydrophobicContact CG1-CB 4.16Å; I464-A495 HydrophobicContact CG2-CB 3.78Å; K479-A495 CarbonylContact O-C 3.46Å; K479-A495 WeakPolarHBondContact O-CA 3.43Å; V480-A495 HydrophobicContact CG2-CB 4.1Å; A495-L578 HydrophobicContact CB-CB 4.12Å; A495-L578 PolarHBondContact O-N 2.96Å; A495-I580 HydrophobicContact CB-CD1 3.94Å; A495-I580 HydrophobicContact CB-CG1 3.92Å
496A93.8Very high79Confident12 Ų1255.9 Ų55.910%0.09932%0.323CS..EExtended strand (participates in β ladder)trans-142.9129.9-17600000111.6V478 K479 T575 V576V478-A496 WeakPolarHBondContact CA-O 3.09Å; K479-A496 PolarHBondContact N-O 3.37Å; K479-A496 PolarHBondContact O-N 3.5Å; A496-T575 HydrophobicContact CB-CG2 4.04Å; A496-V576 CarbonylContact C-O 3.6Å; A496-V576 VanDerWaalsContact CA-O 3.32Å; A496-V576 WeakPolarHBondContact CA-O 3.26Å
497L90.3Very high75.9Confident5 Ų562.5 Ų62.53%0.02635%0.35CS..EExtended strand (participates in β ladder)trans-82.7130.1174.6-165.3152000109.4V468 E499 T575 V576 L578V468-L497 HydrophobicContact CG2-CD1 4.11Å; L497-E499 HydrophobicContact CD2-CG 3.62Å; L497-T575 WeakPolarHBondContact O-CA 3.49Å; L497-V576 PolarHBondContact N-O 3.46Å; L497-V576 PolarHBondContact O-N 3.48Å; L497-L578 HydrophobicContact CB-CD1 4.16Å; L497-L578 HydrophobicContact CB-CD2 4.08Å; L497-L578 HydrophobicContact CB-CG 4.26Å
498V86.9Confident73Confident10 Ų1070.6 Ų70.66%0.06139%0.388CS..EExtended strand (participates in β ladder)trans-100.499179.3-171.70000109.7K477 K479 T573 T575K477-V498 HydrophobicContact CB-CB 4.33Å; K477-V498 PolarHBondContact O-N 2.95Å; K479-V498 HydrophobicContact CD-CG2 3.92Å; K479-V498 HydrophobicContact CG-CG2 4.03Å; V498-T573 HydrophobicContact CG1-CG2 4.13Å; V498-T575 HydrophobicContact CG2-CG2 4Å
499E80.6Confident70.1Confident69 Ų6975.1 Ų75.132%0.32241%0.413SS..EExtended strand (participates in β ladder)trans-76.1137.3171.5-60.6-176.6138.600109.9L497 T573 K574 V576L497-E499 HydrophobicContact CD2-CG 3.62Å; E499-T573 CarbonylContact O-C 3.52Å; E499-T573 VanDerWaalsContact O-CA 3.24Å; E499-T573 WeakPolarHBondContact O-CA 3.48Å; E499-T573 WeakPolarHBondContact O-CB 3.17Å; E499-K574 HydrophobicContact CB-CB 4.26Å; E499-K574 PolarHBondContact N-O 3.38Å; E499-K574 PolarHBondContact O-N 3.39Å; E499-K574 WeakPolarHBondContact OE2-CD 3.24Å; E499-K574 IonicContact OE2-NZ 2.73Å; E499-K574 PolarHBondContact OE2-NZ 3.16Å; E499-V576 HydrophobicContact CG-CG2 4.35Å
500V73.2Confident67.1Low69 Ų6984.2 Ų84.242%0.41846%0.458SS..EExtended strand (participates in β ladder)trans-98.7111.7168.8162.60000106.8K502 V571 T573V500-K502 PolarHBondContact O-N 2.71Å; V500-V571 HydrophobicContact CB-CG1 4.37Å; V500-V571 HydrophobicContact CG1-CG1 3.6Å; V500-V571 HydrophobicContact CG2-CG1 4.22Å; V500-T573 HydrophobicContact CG2-CG2 4.35Å
501I65.9Low64.3Low78 Ų7893 Ų9340%0.450%0.499SS..PPolyproline II helixtrans-75.9116.8166.7-58175.4000105.6K572 K574I501-K572 HydrophobicContact CB-CB 4.48Å; I501-K572 WeakPolarHBondContact CB-O 3.39Å; I501-K572 PolarHBondContact N-O 3.26Å; I501-K574 HydrophobicContact CD1-CB 4.15Å; I501-K574 HydrophobicContact CG1-CB 4.43Å
502K55.4Low61.2Low178 Ų17898.5 Ų98.577%0.77453%0.531SS*.PPolyproline II helixtrans-78.3122.6157.1-69.9-173.7176.2-174.40106.1V500 V504V500-K502 PolarHBondContact O-N 2.71Å; K502-V504 PolarHBondContact O-N 3.13Å
503D45.1Very low58.2Low99 Ų99104.6 Ų104.653%0.52956%0.563SS.*PPolyproline II helixtrans-58.8135.5162.8-58.7-80.7000107.5K572D503-K572 IonicContact OD1-NZ 2.77Å; D503-K572 PolarHBondContact OD1-NZ 3.16Å
504V39.4Very low55.3Low136 Ų136111.3 Ų111.382%0.82459%0.589SS**PPolyproline II helixtrans-85.6128.1-178179.30000108.2K502 G506K502-V504 PolarHBondContact O-N 3.13Å; V504-G506 PolarHBondContact O-N 2.99Å
505E42.5Very low52.1Low200 Ų200113 Ų11394%0.93561%0.613SS**  trans-67.9113.3172.7-65.6173.9142.100109.2
506G35.3Very low49Very low65 Ų65119.7 Ų119.767%0.6765%0.653SS**  trans178116.1-179.900000113.4V504V504-G506 PolarHBondContact O-N 2.99Å
507E29.8Very low45.9Very low194 Ų194127.5 Ų127.591%0.90769%0.685SS**  trans63.796.5169-56.9-169.5163.600117.5P509E507-P509 WeakPolarHBondContact O-CD 3.48Å
508E35.4Very low42.9Very low193 Ų193135.1 Ų135.190%0.90272%0.721SS**PPolyproline II helixtrans-76.9123151.5-64.2179.7152.300109.4
509P34.6Very low40Very low121 Ų121144.1 Ų144.179%0.78676%0.762SS**PPolyproline II helixtrans-76.8134.3157.9-8.426.6000109E507E507-P509 WeakPolarHBondContact O-CD 3.48Å
510M32.1Very low37.5Very low192 Ų192148.9 Ų148.995%0.94678%0.784SS**PPolyproline II helixtrans-61.4155.4174.3-96-177.5162.900112.7
511E37.5Very low35.3Very low185 Ų185151.4 Ų151.486%0.86481%0.805SS**PPolyproline II helixtrans-54.9152-175.6-57.2175.8129.600114.5
512T30.3Very low33.5Very low147 Ų147156.4 Ų156.490%0.90282%0.824SS**  trans-148.1115.6134.8-10.70000109.2
513D33.2Very low32.2Very low145 Ų145157 Ų15778%0.77583%0.832SS**  trans-84.2121.3-179.3177.328.1000111.7
514Q30.9Very low31.3Very low194 Ų194160.8 Ų160.891%0.90785%0.846SS**  trans-179.3131.6154.5-108.115488.800111.7
515G28Very low30.8Very low79 Ų79160.1 Ų160.181%0.81484%0.842SS**  trans139.381.2162.500000115.6
516V29.8Very low30.1Very low142 Ų142158.1 Ų158.186%0.86184%0.838SS**  trans-80.5128.1172.3-171.20000110.4
517K27.4Very low29.8Very low177 Ų177162.5 Ų162.577%0.7784%0.841SS**  169.1169.3129-96.8-179.1178.6-1680115.5
518E26.6Very low29.8Very low165 Ų165161 Ų16177%0.77183%0.833SS**  trans64.8100167.7-73.5140.8-128.600115
519E27.5Very low29.4Very low198 Ų198158.1 Ų158.193%0.92583%0.825SS**  68.4139.962.9-69.8-157.7130.200115.7
520E28.5Very low29.1Very low170 Ų170161.4 Ų161.479%0.79483%0.829SS**  trans-74.6151.2-177.1-54.9-173.6136.200112
521S25.4Very low28.8Very low122 Ų122161.6 Ų161.685%0.85383%0.825SS**  trans-146.2115.1155.2-84.60000111.8
522K28.9Very low28.8Very low183 Ų183157.5 Ų157.580%0.79681%0.814SS**  trans-74.4123.5167.7-63.8161.3-175.6158.60107.9Q524K522-Q524 PolarHBondContact O-N 3.37Å
523M27.2Very low28.6Very low191 Ų191159.3 Ų159.394%0.94181%0.812SS**  trans-81.993161.4-79.7-171.2168.900109.6
524Q27.4Very low28.2Very low178 Ų178156.8 Ų156.883%0.83281%0.812SS**  trans-96.3128.7154.5-172.8169.1-10.500106.6K522K522-Q524 PolarHBondContact O-N 3.37Å
525V28.1Very low28Very low122 Ų122151 Ų15174%0.73980%0.804SS**  trans-91.5125.9-175.9179.30000109.4
526D28.3Very low27.9Very low157 Ų157154.3 Ų154.384%0.8480%0.803SS**  trans-156.3159.9153.4-106.9-39.4000110.3
527H29.4Very low27.7Very low157 Ų157154 Ų15473%0.72780%0.797SS**  trans-92162.8-169.5-110.7-103.7000114.8
528E29Very low27.6Very low162 Ų162152.2 Ų152.276%0.75779%0.791SS**  trans-19.4159.2154-60.7164.3134.400118.7
529D27.9Very low27.7Very low134 Ų134150.1 Ų150.172%0.71779%0.785SS**  cis-174.1136.3-24.4-175.610.8000107.1
530Q27.7Very low27.7Very low189 Ų189147.6 Ų147.688%0.88377%0.771SS**  trans173.2156.8147.5-99.3159.672.900113.1
531K25.3Very low27.5Very low197 Ų197147.5 Ų147.586%0.85777%0.768SS**  trans-137.2174.8-173.6-120.1177.7-177171.90107.9
532P38.4Very low27.4Very low99 Ų99146 Ų14664%0.64376%0.758SS**  cis-138.7-163.9-2.635.7-13000114.5
533Q26.3Very low27.2Very low184 Ų184144.9 Ų144.986%0.8676%0.755SS**  trans76.1149.8158.5-67.5175.8-5.400118.6
534A25.3Very low27.1Very low93 Ų93139.6 Ų139.677%0.76974%0.742SS**  cis-167.6151-23.500000111.4
535G25.8Very low27Very low71 Ų71138.9 Ų138.973%0.73274%0.739SS**  trans72.3170.8167.100000116.1
536D24.8Very low26.9Very low150 Ų150140.3 Ų140.380%0.80274%0.737SS**  cis-167.7160.5-30.1-133.7-13.9000108.1
537N26.4Very low26.7Very low135 Ų135139.8 Ų139.872%0.72273%0.731SS**  trans60.1169.9167.6-70.95000118.8
538E26.2Very low26.5Very low139 Ų139139.8 Ų139.865%0.6573%0.732SS**  -166.3-178.6-55.7-125.7-157.7127.300108.2K540E538-K540 IonicContact OE1-NZ 2.73Å; E538-K540 PolarHBondContact OE1-NZ 2.94Å
539D27.2Very low26.2Very low121 Ų121138.9 Ų138.965%0.64774%0.737SS**  trans65.3123.9170.4-68.7-24.3000118.6
540K27.4Very low26.1Very low145 Ų145137.4 Ų137.463%0.6374%0.738SS**  cis80.5106.940.7-62.6-177.2-146.81030114.4E538E538-K540 IonicContact OE1-NZ 2.73Å; E538-K540 PolarHBondContact OE1-NZ 2.94Å
541K24.9Very low26.4Very low168 Ų168134.3 Ų134.373%0.7373%0.734SS**  -178.5137.1115.4-95.4178173.5-130.90108.8E543K541-E543 IonicContact NZ-OE1 3.7Å; K541-E543 PolarHBondContact NZ-OE1 3.23Å
542S24.6Very low26.3Very low92 Ų92133.7 Ų133.764%0.64373%0.734SS**  cis79.595.114.890.50000117.4
543E23.9Very low25.7Very low159 Ų159134.7 Ų134.774%0.74373%0.734SS**  trans-173.4132.6143.2-92.8141.5-141.100104.4K541K541-E543 IonicContact NZ-OE1 3.7Å; K541-E543 PolarHBondContact NZ-OE1 3.23Å
544A24.6Very low25.6Very low79 Ų79133.1 Ų133.165%0.65374%0.736SS**  cis73.4137.645.400000111.8
545E26.2Very low25.7Very low164 Ų164136.6 Ų136.677%0.76673%0.734SS**  cis-163.3153.25.6-126.7153.3-148.700110.4
546E25.1Very low25.6Very low152 Ų152141.7 Ų141.771%0.7174%0.739SS**  trans48.9164.3138.3-72.7-173.9171.700123.5
547M24.8Very low25.6Very low145 Ų145141.8 Ų141.871%0.71474%0.735SS**  cis-148.5-177.7-3.8-133-171.7-172.300114.1
548E25Very low25.7Very low158 Ų158143.2 Ų143.274%0.73874%0.735SS**  trans-76.1177.8-171.8-49.7171.3121.400117
549T21.7Very low25.6Very low143 Ų143146 Ų14688%0.87775%0.745SS**  trans-150.7147.1130.1210000111.8
550S26.3Very low25.6Very low103 Ų103147.4 Ų147.472%0.7275%0.752SS**  trans-148.7158.5171.6-64.30000108.3
551P34.9Very low25.8Very low124 Ų124146.8 Ų146.881%0.80576%0.755SS**  -140.4-15584.727.9-2.4000111.1
552E22.8Very low26Very low184 Ų184147.1 Ų147.186%0.8676%0.76SS**  cis-144.8173.214.3-67.1-177.492.200112.6
553D24.8Very low26.4Very low120 Ų120148 Ų14864%0.64276%0.763SS**  trans-90.1151.8175.5-83.4-99.7000114.2K555D553-K555 VanDerWaalsContact OD1-CE 3.29Å; D553-K555 WeakPolarHBondContact OD1-CE 3.37Å; D553-K555 IonicContact OD1-NZ 3.75Å
554V25.8Very low26.9Very low150 Ų150146.6 Ų146.691%0.90977%0.768SS**  -146.6149.3123.6174.60000108.8
555K27.4Very low27.4Very low167 Ų167151.3 Ų151.373%0.72678%0.776SS**  trans-116.7147-173-64.9162.3-178.9151.50113.5D553D553-K555 VanDerWaalsContact OD1-CE 3.29Å; D553-K555 WeakPolarHBondContact OD1-CE 3.37Å; D553-K555 IonicContact OD1-NZ 3.75Å
556E23.2Very low27.8Very low177 Ų177147.7 Ų147.783%0.82777%0.774SS**  trans178.9155.9130.6-99.2179.3-170.200107.9
557E24.7Very low28.5Very low152 Ų152150.6 Ų150.671%0.7179%0.785SS**  cis-136.6-170.333.8-87.6-152.299.200115.9
558K27.5Very low29Very low166 Ų166153 Ų15372%0.72279%0.791SS**  trans-72.2164.1-160.6-60.7125.2-170.7151.10118.2
559K25.8Very low29.7Very low198 Ų198149.5 Ų149.586%0.86179%0.789SS**  trans-84.4151162.2-65.1176.8175.4178.60112.6
560N27.3Very low30.8Very low149 Ų149152.7 Ų152.780%0.79779%0.791SS**  trans-178.9151.7134.2-111.435.6000108.5
561D31.3Very low32.3Very low132 Ų132151.7 Ų151.771%0.70678%0.78SS**  cis-161.2139.2-20.1-152.7-11.5000108
562Q29.4Very low33.8Very low176 Ų176151.7 Ų151.782%0.82277%0.768SS**  trans-169.8141.8168.6-115.5173.365.100112
563P32.3Very low36.1Very low109 Ų109147 Ų14771%0.70875%0.751SS**PPolyproline II helixtrans-77.9157.3-172.931.6-35.8000113.5Q565P563-Q565 PolarHBondContact O-N 3.38Å
564P35.1Very low38.9Very low130 Ų130146.2 Ų146.284%0.84474%0.742SS**PPolyproline II helixtrans-66.7125.5-177.827.2-34.8000111.9A566P564-A566 PolarHBondContact O-N 2.82Å
565Q34.1Very low41.7Very low178 Ų178143 Ų14383%0.83272%0.723SS**PPolyproline II helixtrans-66.8121.4171.9-68.8-168.611.700110.4P563P563-Q565 PolarHBondContact O-N 3.38Å
566A34Very low44.6Very low88 Ų88137.6 Ų137.673%0.72770%0.704SS**PPolyproline II helixtrans-58.2138.9176.500000111.5P564 K568P564-A566 PolarHBondContact O-N 2.82Å; A566-K568 PolarHBondContact O-N 3.08Å
567K40.1Very low48Very low214 Ų214135.1 Ų135.193%0.9370%0.696SS**  trans-60.1106.5171.3-71.2-180179.1175.80108.7A569K567-A569 PolarHBondContact O-N 2.8Å
568K35.2Very low51.2Low195 Ų195128.6 Ų128.685%0.84867%0.666SS**  trans-59.3131.4178.2-69.3-179.4178.9175.30110A566A566-K568 PolarHBondContact O-N 3.08Å
569A40.7Very low54.4Low85 Ų85123.3 Ų123.370%0.70265%0.649SS**  trans-56.6145.8175.500000111.4K567 V571K567-A569 PolarHBondContact O-N 2.8Å; A569-V571 VanDerWaalsContact C-N 3.28Å; A569-V571 PolarHBondContact O-N 3.09Å
570K44.8Very low57.7Low210 Ų210116.5 Ų116.591%0.91362%0.622SS**  trans-73.581.6174.4-78.9-174.5175.6178.40110.2K572K570-K572 PolarHBondContact O-N 3.1Å
571V57.4Low60.8Low81 Ų81114.7 Ų114.749%0.49161%0.608SS.*  trans-53.4120.1173.8176.30000110.3V500 A569 T573V500-V571 HydrophobicContact CB-CG1 4.37Å; V500-V571 HydrophobicContact CG1-CG1 3.6Å; V500-V571 HydrophobicContact CG2-CG1 4.22Å; A569-V571 VanDerWaalsContact C-N 3.28Å; A569-V571 PolarHBondContact O-N 3.09Å; V571-T573 HydrophobicContact CG1-CG2 4.3Å; V571-T573 PolarHBondContact O-N 3.25Å
572K65.6Low63.7Low125 Ų125110.6 Ų110.654%0.54360%0.597SS.*  trans-70.9118.8171.9-65.9170.7-168.6150.60109I501 D503 K570I501-K572 HydrophobicContact CB-CB 4.48Å; I501-K572 WeakPolarHBondContact CB-O 3.39Å; I501-K572 PolarHBondContact N-O 3.26Å; D503-K572 IonicContact OD1-NZ 2.77Å; D503-K572 PolarHBondContact OD1-NZ 3.16Å; K570-K572 PolarHBondContact O-N 3.1Å
573T72.6Confident66.7Low84 Ų84108.2 Ų108.252%0.51558%0.584SS.*EExtended strand (participates in β ladder)trans-109128.9176.257.60000110.9V498 E499 V500 V571V498-T573 HydrophobicContact CG1-CG2 4.13Å; E499-T573 CarbonylContact O-C 3.52Å; E499-T573 VanDerWaalsContact O-CA 3.24Å; E499-T573 WeakPolarHBondContact O-CA 3.48Å; E499-T573 WeakPolarHBondContact O-CB 3.17Å; V500-T573 HydrophobicContact CG2-CG2 4.35Å; V571-T573 HydrophobicContact CG1-CG2 4.3Å; V571-T573 PolarHBondContact O-N 3.25Å
574K82.3Confident69.5Low104 Ų104104.7 Ų104.745%0.45256%0.559SS.*EExtended strand (participates in β ladder)trans-95.2140.8169.7172.2168.2163.9-104.70108.8E499 I501 V576E499-K574 HydrophobicContact CB-CB 4.26Å; E499-K574 PolarHBondContact N-O 3.38Å; E499-K574 PolarHBondContact O-N 3.39Å; E499-K574 WeakPolarHBondContact OE2-CD 3.24Å; E499-K574 IonicContact OE2-NZ 2.73Å; E499-K574 PolarHBondContact OE2-NZ 3.16Å; I501-K574 HydrophobicContact CD1-CB 4.15Å; I501-K574 HydrophobicContact CG1-CB 4.43Å; K574-V576 HydrophobicContact CG-CG2 4.49Å
575T85.3Confident72Confident83 Ų83100 Ų10051%0.50953%0.526SS..EExtended strand (participates in β ladder)trans-108136.9171.410.50000109.6A496 L497 V498A496-T575 HydrophobicContact CB-CG2 4.04Å; L497-T575 WeakPolarHBondContact O-CA 3.49Å; V498-T575 HydrophobicContact CG2-CG2 4Å
576V89.1Confident74.6Confident53 Ų5394.4 Ų94.432%0.32150%0.497SS..EExtended strand (participates in β ladder)trans-121.1117.8174.8-179.80000107.2A496 L497 E499 K574A496-V576 CarbonylContact C-O 3.6Å; A496-V576 VanDerWaalsContact CA-O 3.32Å; A496-V576 WeakPolarHBondContact CA-O 3.26Å; L497-V576 PolarHBondContact N-O 3.46Å; L497-V576 PolarHBondContact O-N 3.48Å; E499-V576 HydrophobicContact CG-CG2 4.35Å; K574-V576 HydrophobicContact CG-CG2 4.49Å
577D93.2Very high77.2Confident125 Ų12594 Ų9467%0.66848%0.48SS*.EExtended strand (participates in β ladder)trans-70.6142.1177.3-66.9-48.4000110.8
578L93.1Very high79.7Confident15 Ų1584.7 Ų84.78%0.07944%0.441CS..  trans-113.4135.1-173.5-59.9178.8000110.1I464 N466 V467 V478 A495 L497I464-L578 HydrophobicContact CG2-CB 4.04Å; I464-L578 HydrophobicContact CG2-CD1 3.67Å; N466-L578 HydrophobicContact CB-CD2 4.4Å; V467-L578 HydrophobicContact CG2-CD1 3.69Å; V478-L578 HydrophobicContact CG1-CD1 3.74Å; V478-L578 HydrophobicContact CG2-CD1 4.28Å; A495-L578 HydrophobicContact CB-CB 4.12Å; A495-L578 PolarHBondContact O-N 2.96Å; L497-L578 HydrophobicContact CB-CD1 4.16Å; L497-L578 HydrophobicContact CB-CD2 4.08Å; L497-L578 HydrophobicContact CB-CG 4.26Å
579P94.5Very high82.5Confident56 Ų5678.9 Ų78.936%0.36442%0.423SS..  trans-61.3142.7172.9-18.731000111.3Q465Q465-P579 HydrophobicContact CB-CB 4.19Å; Q465-P579 PolarHBondContact N-O 2.82Å
580I94.6Very high84.9Confident55 Ų5579.8 Ų79.828%0.28242%0.419SS..EExtended strand (participates in β ladder)trans-120.7121.4174.6-60.2154.2000107.5F462 L463 V492 A495F462-I580 HydrophobicContact CB-CG2 4.32Å; F462-I580 HydrophobicContact CD1-CG2 4.29Å; L463-I580 WeakPolarHBondContact O-CA 3.48Å; V492-I580 HydrophobicContact CB-CD1 4.32Å; V492-I580 HydrophobicContact CB-CG2 4.26Å; V492-I580 HydrophobicContact CG1-CD1 3.63Å; V492-I580 HydrophobicContact CG1-CG1 4.31Å; V492-I580 HydrophobicContact CG1-CG2 4.35Å; A495-I580 HydrophobicContact CB-CD1 3.94Å; A495-I580 HydrophobicContact CB-CG1 3.92Å
581E93.3Very high87.3Confident110 Ų11077.4 Ų77.451%0.51441%0.412SS..EExtended strand (participates in β ladder)trans-99.9122.1170.6-179.3-177.9176.300108.3F462 L463 Q465F462-E581 CarbonylContact C-O 3.58Å; F462-E581 WeakPolarHBondContact CA-O 3.45Å; L463-E581 HydrophobicContact CB-CB 4.33Å; L463-E581 PolarHBondContact N-O 3.47Å; L463-E581 PolarHBondContact O-N 3.12Å; Q465-E581 PolarHBondContact NE2-OE2 3.28Å
582G91.6Very high89.1Confident46 Ų4676 Ų7647%0.47440%0.4SS..EExtended strand (participates in β ladder)trans-117123.7-173.500000112.4
583K91.6Very high90.5Very high126 Ų12670.6 Ų70.655%0.54838%0.377SS..EExtended strand (participates in β ladder)trans-116.496.6178.2177.8178.7158.8-138.20109.4G460 E461G460-K583 CarbonylContact C-O 3.6Å; G460-K583 VanDerWaalsContact CA-O 3.23Å; G460-K583 WeakPolarHBondContact CA-O 3.49Å; E461-K583 HydrophobicContact CB-CB 4.4Å; E461-K583 PolarHBondContact N-O 3.36Å; E461-K583 PolarHBondContact O-N 3.12Å; E461-K583 IonicContact OE1-NZ 2.75Å; E461-K583 PolarHBondContact OE1-NZ 3.2Å; E461-K583 WeakPolarHBondContact OE2-CD 3.32Å; E461-K583 IonicContact OE2-NZ 2.69Å; E461-K583 PolarHBondContact OE2-NZ 2.72Å
584L91.6Very high91.7Very high36 Ų3670.8 Ų70.819%0.18838%0.375CS..EExtended strand (participates in β ladder)trans-91.7150.1-175.7-71.4153.1000111.2I459 F462 W586 Q587I459-L584 HydrophobicContact CG2-CD2 4.33Å; F462-L584 HydrophobicContact CE1-CD2 4.5Å; F462-L584 HydrophobicContact CZ-CD2 3.9Å; L584-W586 PolarHBondContact O-N 3.09Å; L584-Q587 HydrophobicContact CB-CB 4.31Å; L584-Q587 VanDerWaalsContact CD1-OE1 3.23Å
585Q86.8Confident92.4Very high32 Ų3269.2 Ų69.215%0.1537%0.374CS..SBendtrans-72.9126176.7-62.8-64.6-66.100110.6T458 I459 Q587T458-Q585 HydrophobicContact CG2-CG 4.32Å; T458-Q585 VanDerWaalsContact O-CG 3.31Å; T458-Q585 WeakPolarHBondContact O-CG 3.44Å; I459-Q585 PolarHBondContact O-N 3.01Å; Q585-Q587 PolarHBondContact O-N 2.93Å; Q585-Q587 VanDerWaalsContact O-N 3.1Å
586W88.6Confident93Very high60 Ų6066 Ų6623%0.22735%0.353CS..SBendtrans58.616.1171.3-42.7104.8000117.4A74 A98 Y454 L584A74-W586 HydrophobicContact CB-CH2 3.58Å; A74-W586 HydrophobicContact CB-CZ2 3.49Å; A74-W586 VanDerWaalsContact CB-CZ2 3.49Å; A74-W586 HydrophobicContact CB-CZ3 4.36Å; A98-W586 HydrophobicContact CB-CE3 4.35Å; Y454-W586 PolarHBondContact OH-NE1 2.85Å; L584-W586 PolarHBondContact O-N 3.09Å
587Q89.9Confident93.5Very high79 Ų7966.2 Ų66.237%0.36935%0.354SS..PPolyproline II helixtrans-72.5140.1164.6-172.9171.43.900109.6L584 Q585L584-Q587 HydrophobicContact CB-CB 4.31Å; L584-Q587 VanDerWaalsContact CD1-OE1 3.23Å; Q585-Q587 PolarHBondContact O-N 2.93Å; Q585-Q587 VanDerWaalsContact O-N 3.1Å
588L92.5Very high93.7Very high18 Ų1865.8 Ų65.89%0.09435%0.348CS..PPolyproline II helixtrans-69.3138.2176.6-65.7179.8000111.2E115 D158 L593 F596E115-L588 HydrophobicContact CB-CD1 4.1Å; E115-L588 HydrophobicContact CG-CD1 3.98Å; E115-L588 HydrophobicContact CG-CG 4.43Å; D158-L588 HydrophobicContact CB-CD1 4.26Å; D158-L588 PolarHBondContact OD2-N 2.89Å; L588-L593 HydrophobicContact CB-CB 4.33Å; L588-L593 HydrophobicContact CD1-CD1 4.26Å; L588-F596 HydrophobicContact CD1-CD2 3.68Å; L588-F596 HydrophobicContact CD1-CE2 3.68Å; L588-F596 HydrophobicContact CD2-CE2 4.16Å
589P92.8Very high93.9Very high74 Ų7467.7 Ų67.748%0.48136%0.358SS..PPolyproline II helixtrans-57.5145164.7-22.133.2000111.1E591 E592 L593P589-E591 PolarHBondContact O-N 3.02Å; P589-E592 HydrophobicContact CB-CB 4.37Å; P589-E592 WeakPolarHBondContact CD-OE2 3.33Å; P589-E592 HydrophobicContact CG-CB 4.5Å; P589-E592 PolarHBondContact O-N 2.92Å; P589-E592 VanDerWaalsContact O-N 3.08Å; P589-L593 PolarHBondContact O-N 3.44Å
590V92.9Very high94.1Very high103 Ų10365.2 Ų65.262%0.62434%0.342SS*.Hα-helixtrans-57.9-34.7-177.6-179.90000112.1N594V590-N594 WeakPolarHBondContact O-CB 3.4Å; V590-N594 PolarHBondContact O-N 3.41Å; V590-N594 PolarHBondContact O-ND2 3.26Å
591E94.6Very high94.2Very high161 Ų16164.4 Ų64.475%0.75235%0.347SS*.Hα-helixtrans-68.6-40.9177.3-61.2178.1171.400112.6P589 T595P589-E591 PolarHBondContact O-N 3.02Å; E591-T595 WeakPolarHBondContact O-CB 3.45Å; E591-T595 PolarHBondContact O-N 2.99Å; E591-T595 PolarHBondContact O-OG1 3.07Å
592E94.6Very high94.4Very high51 Ų5164.3 Ų64.324%0.23835%0.345CS..Hα-helixtrans-69-41.9175.6-173.9170.2-159.400110.5P589 T595 F596P589-E592 HydrophobicContact CB-CB 4.37Å; P589-E592 WeakPolarHBondContact CD-OE2 3.33Å; P589-E592 HydrophobicContact CG-CB 4.5Å; P589-E592 PolarHBondContact O-N 2.92Å; P589-E592 VanDerWaalsContact O-N 3.08Å; E592-T595 WeakPolarHBondContact O-CB 3.34Å; E592-T595 PolarHBondContact O-N 3.47Å; E592-F596 HydrophobicContact CG-CD1 4.4Å; E592-F596 HydrophobicContact CG-CE1 3.76Å; E592-F596 HydrophobicContact CG-CE2 3.96Å; E592-F596 HydrophobicContact CG-CZ 3.51Å; E592-F596 WeakPolarHBondContact O-CD1 3.42Å; E592-F596 WeakPolarHBondContact O-CG 3.37Å; E592-F596 PolarHBondContact O-N 3.1Å; E592-F596 WeakPolarHBondContact OE1-CZ 3.08Å
593L95.9Very high94.7Very high11 Ų1162.8 Ų62.86%0.05833%0.326CS..Hα-helixtrans-61-46.6175.1-178.459.7000112.2D158 Q161 I162 L588 P589 T595 F596 V597D158-L593 HydrophobicContact CB-CD1 4.07Å; Q161-L593 HydrophobicContact CB-CD1 4.32Å; Q161-L593 HydrophobicContact CB-CD2 4.33Å; I162-L593 HydrophobicContact CD1-CD1 4.16Å; I162-L593 HydrophobicContact CG1-CD1 3.71Å; L588-L593 HydrophobicContact CB-CB 4.33Å; L588-L593 HydrophobicContact CD1-CD1 4.26Å; P589-L593 PolarHBondContact O-N 3.44Å; L593-T595 VanDerWaalsContact C-N 3.32Å; L593-T595 PolarHBondContact O-N 3.47Å; L593-F596 PolarHBondContact O-N 3.45Å; L593-F596 VanDerWaalsContact O-N 3.12Å; L593-V597 WeakPolarHBondContact O-CG2 3.44Å; L593-V597 PolarHBondContact O-N 2.87Å
594N97.1Very high95Very high89 Ų8959.5 Ų59.548%0.47631%0.314SS..Hα-helixtrans-60.6-41.6174.6-73-19.3000111.6V590 F596 V597 E598V590-N594 WeakPolarHBondContact O-CB 3.4Å; V590-N594 PolarHBondContact O-N 3.41Å; V590-N594 PolarHBondContact O-ND2 3.26Å; N594-F596 VanDerWaalsContact C-N 3.27Å; N594-F596 PolarHBondContact O-N 3.19Å; N594-V597 PolarHBondContact O-N 3.49Å; N594-E598 PolarHBondContact O-N 2.97Å
595T97.4Very high95.3Very high70 Ų7062.5 Ų62.543%0.42933%0.328SS..Hα-helixtrans-60.6-37.6174.6-580000111.5E591 E592 L593 N599E591-T595 WeakPolarHBondContact O-CB 3.45Å; E591-T595 PolarHBondContact O-N 2.99Å; E591-T595 PolarHBondContact O-OG1 3.07Å; E592-T595 WeakPolarHBondContact O-CB 3.34Å; E592-T595 PolarHBondContact O-N 3.47Å; L593-T595 VanDerWaalsContact C-N 3.32Å; L593-T595 PolarHBondContact O-N 3.47Å; T595-N599 WeakPolarHBondContact O-CB 3.37Å; T595-N599 PolarHBondContact O-N 3.41Å; T595-N599 VanDerWaalsContact O-N 3.07Å; T595-N599 PolarHBondContact O-ND2 2.9Å
596F97.8Very high95.8Very high17 Ų1763.6 Ų63.68%0.07533%0.333CS..Hα-helixtrans-71.4-38.4176.4-67.1-2.3000112.5M94 Q116 I162 L588 E592 L593 N594 N599 E600M94-F596 HydrophobicContact CE-CZ 4.31Å; Q116-F596 HydrophobicContact CG-CB 4.1Å; Q116-F596 HydrophobicContact CG-CD1 4.23Å; Q116-F596 HydrophobicContact CG-CD2 3.46Å; Q116-F596 VanDerWaalsContact CG-CD2 3.46Å; Q116-F596 HydrophobicContact CG-CE2 3.85Å; Q116-F596 HydrophobicContact CG-CG 3.67Å; Q116-F596 HydrophobicContact CG-CZ 4.39Å; Q116-F596 VanDerWaalsContact NE2-CD1 3.3Å; I162-F596 HydrophobicContact CD1-CB 3.8Å; I162-F596 HydrophobicContact CD1-CD2 3.9Å; I162-F596 HydrophobicContact CD1-CG 4.37Å; I162-F596 HydrophobicContact CG1-CB 3.86Å; L588-F596 HydrophobicContact CD1-CD2 3.68Å; L588-F596 HydrophobicContact CD1-CE2 3.68Å; L588-F596 HydrophobicContact CD2-CE2 4.16Å; E592-F596 HydrophobicContact CG-CD1 4.4Å; E592-F596 HydrophobicContact CG-CE1 3.76Å; E592-F596 HydrophobicContact CG-CE2 3.96Å; E592-F596 HydrophobicContact CG-CZ 3.51Å; E592-F596 WeakPolarHBondContact O-CD1 3.42Å; E592-F596 WeakPolarHBondContact O-CG 3.37Å; E592-F596 PolarHBondContact O-N 3.1Å; E592-F596 WeakPolarHBondContact OE1-CZ 3.08Å; L593-F596 PolarHBondContact O-N 3.45Å; L593-F596 VanDerWaalsContact O-N 3.12Å; N594-F596 VanDerWaalsContact C-N 3.27Å; N594-F596 PolarHBondContact O-N 3.19Å; F596-N599 PolarHBondContact O-N 3.11Å; F596-E600 WeakPolarHBondContact O-CB 3.48Å; F596-E600 PolarHBondContact O-N 2.98Å
597V98.2Very high96.2Very high57 Ų5762 Ų6235%0.34533%0.329SS..Hα-helixtrans-58.9-47.8171.9173.60000111L593 N594 N599 E600 G601L593-V597 WeakPolarHBondContact O-CG2 3.44Å; L593-V597 PolarHBondContact O-N 2.87Å; N594-V597 PolarHBondContact O-N 3.49Å; V597-N599 VanDerWaalsContact C-N 3.33Å; V597-N599 PolarHBondContact O-N 3.41Å; V597-E600 PolarHBondContact O-N 3.39Å; V597-G601 PolarHBondContact O-N 3.32Å
598E98Very high96.5Very high115 Ų11563.7 Ų63.754%0.53734%0.335SS..Hα-helixtrans-61-42.1176.7-77-168.1-163.300112.6N594 G601 K602N594-E598 PolarHBondContact O-N 2.97Å; E598-G601 PolarHBondContact O-N 2.64Å; E598-K602 VanDerWaalsContact O-CG 3.29Å; E598-K602 WeakPolarHBondContact O-CG 3.31Å; E598-K602 PolarHBondContact O-N 2.74Å; E598-K602 IonicContact OE2-NZ 3.35Å; E598-K602 PolarHBondContact OE2-NZ 3.11Å
599N97.4Very high96.6Very high56 Ų5666.5 Ų66.530%0.29935%0.35SS..Hα-helixtrans-71.7-34.9-177.5-68.7-18.5000111.8T595 F596 V597 K602 M603T595-N599 WeakPolarHBondContact O-CB 3.37Å; T595-N599 PolarHBondContact O-N 3.41Å; T595-N599 VanDerWaalsContact O-N 3.07Å; T595-N599 PolarHBondContact O-ND2 2.9Å; F596-N599 PolarHBondContact O-N 3.11Å; V597-N599 VanDerWaalsContact C-N 3.33Å; V597-N599 PolarHBondContact O-N 3.41Å; N599-K602 PolarHBondContact O-N 3.14Å; N599-K602 PolarHBondContact OD1-NZ 3.21Å; N599-M603 WeakPolarHBondContact O-CE 3.49Å; N599-M603 WeakPolarHBondContact O-CG 3.36Å; N599-M603 PolarHBondContact O-N 2.67Å
600E98.3Very high96.8Very high3 Ų363.9 Ų63.91%0.01433%0.331CS..Hα-helixtrans-59.4-46167.2179.259.4-156.500111R46 T123 I162 F596 V597 K602 M603 I604R46-E600 IonicContact CZ-OE1 2.68Å; R46-E600 IonicContact CZ-OE2 2.68Å; R46-E600 VanDerWaalsContact NH1-CD 3.31Å; R46-E600 IonicContact NH1-OE1 3.7Å; R46-E600 PolarHBondContact NH1-OE1 2.82Å; R46-E600 IonicContact NH1-OE2 2.74Å; R46-E600 PolarHBondContact NH1-OE2 3.48Å; R46-E600 IonicContact NH2-OE1 3.54Å; R46-E600 PolarHBondContact NH2-OE1 3.19Å; R46-E600 IonicContact NH2-OE2 3.01Å; T123-E600 WeakPolarHBondContact CB-OE1 3.33Å; T123-E600 PolarHBondContact OG1-OE1 3.12Å; I162-E600 HydrophobicContact CG2-CB 3.75Å; I162-E600 HydrophobicContact CG2-CG 4.04Å; I162-E600 WeakPolarHBondContact O-CG 3.15Å; F596-E600 WeakPolarHBondContact O-CB 3.48Å; F596-E600 PolarHBondContact O-N 2.98Å; V597-E600 PolarHBondContact O-N 3.39Å; E600-K602 VanDerWaalsContact C-N 3.34Å; E600-K602 PolarHBondContact O-N 3.14Å; E600-M603 PolarHBondContact O-N 2.91Å; E600-I604 HydrophobicContact CG-CD1 3.93Å; E600-I604 HydrophobicContact CG-CG1 4.45Å; E600-I604 VanDerWaalsContact O-CG1 3.27Å; E600-I604 WeakPolarHBondContact O-CG1 3.37Å; E600-I604 PolarHBondContact O-N 2.61Å
601G97.8Very high96.9Very high38 Ų3864.9 Ų64.939%0.39233%0.327SS..Hα-helixtrans-57.9-41.5174.600000113.7V597 E598 M605V597-G601 PolarHBondContact O-N 3.32Å; E598-G601 PolarHBondContact O-N 2.64Å; G601-M605 PolarHBondContact O-N 3.18Å; G601-M605 VanDerWaalsContact O-N 3.08Å
602K97.8Very high96.9Very high109 Ų10960 Ų6047%0.47430%0.304SS..Hα-helixtrans-63.9-44.6175.2-66.7159.6-155.5161.10111.3E598 N599 E600 M605 Q606E598-K602 VanDerWaalsContact O-CG 3.29Å; E598-K602 WeakPolarHBondContact O-CG 3.31Å; E598-K602 PolarHBondContact O-N 2.74Å; E598-K602 IonicContact OE2-NZ 3.35Å; E598-K602 PolarHBondContact OE2-NZ 3.11Å; N599-K602 PolarHBondContact O-N 3.14Å; N599-K602 PolarHBondContact OD1-NZ 3.21Å; E600-K602 VanDerWaalsContact C-N 3.34Å; E600-K602 PolarHBondContact O-N 3.14Å; K602-M605 PolarHBondContact O-N 2.96Å; K602-Q606 PolarHBondContact O-N 3.26Å
603M98Very high97Very high14 Ų1459 Ų597%0.06930%0.298CS..Hα-helixtrans-65.5-42.4176.7-70-177.4-69.100112.5Y105 F112 M120 N599 E600 M605 Q606 D607Y105-M603 HydrophobicContact CE1-CG 4.04Å; Y105-M603 HydrophobicContact CE1-SD 4.04Å; F112-M603 HydrophobicContact CE1-CE 4.12Å; F112-M603 HydrophobicContact CE1-SD 3.84Å; F112-M603 HydrophobicContact CZ-SD 4.01Å; M120-M603 HydrophobicContact CE-CE 3.69Å; M120-M603 HydrophobicContact CE-SD 3.99Å; N599-M603 WeakPolarHBondContact O-CE 3.49Å; N599-M603 WeakPolarHBondContact O-CG 3.36Å; N599-M603 PolarHBondContact O-N 2.67Å; E600-M603 PolarHBondContact O-N 2.91Å; M603-M605 VanDerWaalsContact C-N 3.3Å; M603-M605 PolarHBondContact O-N 2.97Å; M603-Q606 PolarHBondContact O-N 3.46Å; M603-D607 PolarHBondContact O-N 3.48Å
604I97.7Very high97Very high57 Ų5761 Ų6129%0.29231%0.309SS..Hα-helixtrans-57.5-43.5174-68.7167.5000111.2T123 E600 K608T123-I604 HydrophobicContact CG2-CD1 3.63Å; T123-I604 HydrophobicContact CG2-CG1 3.81Å; E600-I604 HydrophobicContact CG-CD1 3.93Å; E600-I604 HydrophobicContact CG-CG1 4.45Å; E600-I604 VanDerWaalsContact O-CG1 3.27Å; E600-I604 WeakPolarHBondContact O-CG1 3.37Å; E600-I604 PolarHBondContact O-N 2.61Å; I604-K608 WeakPolarHBondContact O-CB 3.37Å; I604-K608 PolarHBondContact O-N 3.19Å
605M97Very high96.9Very high98 Ų9859.6 Ų59.648%0.48330%0.301SS..Hα-helixtrans-66.7-40.4178.4-172.362.3-177.400111.6G601 K602 M603 K608 L609G601-M605 PolarHBondContact O-N 3.18Å; G601-M605 VanDerWaalsContact O-N 3.08Å; K602-M605 PolarHBondContact O-N 2.96Å; M603-M605 VanDerWaalsContact C-N 3.3Å; M603-M605 PolarHBondContact O-N 2.97Å; M605-K608 PolarHBondContact O-N 3.4Å; M605-L609 HydrophobicContact CE-CD1 4.21Å; M605-L609 HydrophobicContact CE-CD2 4.12Å; M605-L609 HydrophobicContact CE-CG 4.11Å; M605-L609 HydrophobicContact CG-CD1 4.25Å; M605-L609 WeakPolarHBondContact O-CB 3.47Å; M605-L609 VanDerWaalsContact O-CG 3.31Å; M605-L609 WeakPolarHBondContact O-CG 3.43Å; M605-L609 PolarHBondContact O-N 3.09Å
606Q97Very high96.9Very high56 Ų5656.7 Ų56.726%0.26228%0.284SS..Hα-helixtrans-63.9-46175.9179.660.117.700112.1R44 M106 K602 M603 K608 L609 E610R44-Q606 VanDerWaalsContact O-CG 3.25Å; R44-Q606 WeakPolarHBondContact O-CG 3.36Å; R44-Q606 PolarHBondContact O-NE2 2.93Å; M106-Q606 HydrophobicContact CE-CG 4.25Å; M106-Q606 HydrophobicContact SD-CG 4.13Å; K602-Q606 PolarHBondContact O-N 3.26Å; M603-Q606 PolarHBondContact O-N 3.46Å; Q606-K608 VanDerWaalsContact C-N 3.27Å; Q606-K608 PolarHBondContact O-N 2.78Å; Q606-L609 PolarHBondContact O-N 3.33Å; Q606-E610 PolarHBondContact O-N 3.49Å
607D97.1Very high96.9Very high27 Ų2757.1 Ų57.114%0.14429%0.286CS..Hα-helixtrans-58.6-41.1175-64.1-32000111.5N45 R46 M603 K611N45-D607 WeakPolarHBondContact CB-OD1 3.4Å; R46-D607 WeakPolarHBondContact CG-OD1 3.38Å; R46-D607 VanDerWaalsContact CG-OD2 3.25Å; R46-D607 WeakPolarHBondContact CG-OD2 3.07Å; R46-D607 IonicContact CZ-OD2 3.72Å; R46-D607 PolarHBondContact N-OD1 2.92Å; R46-D607 IonicContact NE-OD2 2.8Å; R46-D607 PolarHBondContact NE-OD2 3.44Å; R46-D607 IonicContact NH2-OD2 2.75Å; R46-D607 PolarHBondContact NH2-OD2 2.95Å; M603-D607 PolarHBondContact O-N 3.48Å; D607-K611 WeakPolarHBondContact O-CB 3.44Å; D607-K611 PolarHBondContact O-N 3.19Å
608K95.9Very high96.8Very high113 Ų11358.2 Ų58.249%0.49129%0.29SS..Hα-helixtrans-66.3-44.3177.1179.5-179.1168.3-176.50112I604 M605 Q606 K611 E612I604-K608 WeakPolarHBondContact O-CB 3.37Å; I604-K608 PolarHBondContact O-N 3.19Å; M605-K608 PolarHBondContact O-N 3.4Å; Q606-K608 VanDerWaalsContact C-N 3.27Å; Q606-K608 PolarHBondContact O-N 2.78Å; K608-K611 PolarHBondContact O-N 2.67Å; K608-E612 WeakPolarHBondContact CE-OE1 3.32Å; K608-E612 HydrophobicContact CG-CG 4.46Å; K608-E612 IonicContact NZ-OE1 2.65Å; K608-E612 WeakPolarHBondContact O-CB 3.39Å; K608-E612 WeakPolarHBondContact O-CG 3.34Å; K608-E612 PolarHBondContact O-N 2.97Å
609L95.9Very high96.8Very high78 Ų7856.5 Ų56.541%0.40829%0.285SS..Hα-helixtrans-63.3-44178.7-75.2170.3000111.7M605 Q606 E612 R613M605-L609 HydrophobicContact CE-CD1 4.21Å; M605-L609 HydrophobicContact CE-CD2 4.12Å; M605-L609 HydrophobicContact CE-CG 4.11Å; M605-L609 HydrophobicContact CG-CD1 4.25Å; M605-L609 WeakPolarHBondContact O-CB 3.47Å; M605-L609 VanDerWaalsContact O-CG 3.31Å; M605-L609 WeakPolarHBondContact O-CG 3.43Å; M605-L609 PolarHBondContact O-N 3.09Å; Q606-L609 PolarHBondContact O-N 3.33Å; L609-E612 PolarHBondContact O-N 2.92Å; L609-R613 WeakPolarHBondContact O-CB 3.39Å; L609-R613 PolarHBondContact O-N 3.1Å
610E95.8Very high96.8Very high18 Ų1853.8 Ų53.88%0.08427%0.27CS..Hα-helixtrans-67.2-37.2175.9-179.656.5-159.100111.6R44 N45 Q606 R613 N614R44-E610 HydrophobicContact CB-CG 4.05Å; R44-E610 IonicContact NH1-OE2 2.7Å; N45-E610 HydrophobicContact CB-CB 4.12Å; N45-E610 HydrophobicContact CB-CG 4.09Å; Q606-E610 PolarHBondContact O-N 3.49Å; E610-R613 PolarHBondContact O-N 2.77Å; E610-R613 IonicContact OE1-CZ 3.65Å; E610-R613 IonicContact OE1-NE 3.35Å; E610-R613 PolarHBondContact OE1-NE 3.2Å; E610-R613 IonicContact OE1-NH2 2.73Å; E610-R613 PolarHBondContact OE1-NH2 2.94Å; E610-R613 IonicContact OE2-CZ 2.67Å; E610-R613 IonicContact OE2-NE 2.78Å; E610-R613 PolarHBondContact OE2-NE 3.49Å; E610-R613 IonicContact OE2-NH2 3.41Å; E610-N614 PolarHBondContact O-N 3.49Å; E610-N614 PolarHBondContact O-ND2 3.21Å; E610-N614 PolarHBondContact OE1-ND2 3.27Å
611K94.8Very high96.7Very high125 Ų12556.1 Ų56.154%0.54328%0.281SS..Hα-helixtrans-61.7-50.2171.2-163.9-163.2179.4-93.40111.3D607 K608 R613 N614 D615D607-K611 WeakPolarHBondContact O-CB 3.44Å; D607-K611 PolarHBondContact O-N 3.19Å; K608-K611 PolarHBondContact O-N 2.67Å; K611-R613 PolarHBondContact O-N 3.26Å; K611-N614 PolarHBondContact O-N 3.02Å; K611-N614 VanDerWaalsContact O-N 3.14Å; K611-D615 VanDerWaalsContact NZ-CG 3.26Å; K611-D615 IonicContact NZ-OD1 2.67Å; K611-D615 PolarHBondContact NZ-OD1 2.92Å; K611-D615 IonicContact NZ-OD2 2.78Å; K611-D615 PolarHBondContact NZ-OD2 3.28Å; K611-D615 WeakPolarHBondContact O-CB 3.35Å; K611-D615 VanDerWaalsContact O-CG 3.26Å; K611-D615 PolarHBondContact O-N 3.22Å
612E95.9Very high96.6Very high59 Ų5960.8 Ų60.828%0.27629%0.293SS..Hα-helixtrans-63.7-23.9179.9-74.9-175.2-17100113.2K608 L609 A616 K667K608-E612 WeakPolarHBondContact CE-OE1 3.32Å; K608-E612 HydrophobicContact CG-CG 4.46Å; K608-E612 IonicContact NZ-OE1 2.65Å; K608-E612 WeakPolarHBondContact O-CB 3.39Å; K608-E612 WeakPolarHBondContact O-CG 3.34Å; K608-E612 PolarHBondContact O-N 2.97Å; L609-E612 PolarHBondContact O-N 2.92Å; E612-A616 VanDerWaalsContact O-CB 3.3Å; E612-A616 WeakPolarHBondContact O-CB 3.44Å; E612-A616 PolarHBondContact O-N 2.97Å; E612-K667 HydrophobicContact CB-CD 4.03Å; E612-K667 IonicContact OE2-NZ 2.81Å; E612-K667 PolarHBondContact OE2-NZ 3.42Å
613R96.3Very high96.6Very high28 Ų2856.2 Ų56.211%0.10627%0.273CS..Hα-helixtrans-72.2-47.9171.1-169.7-169.375.375.77.8111.5L609 E610 K611 A616 K617 D664 Q665 K667 Y670L609-R613 WeakPolarHBondContact O-CB 3.39Å; L609-R613 PolarHBondContact O-N 3.1Å; E610-R613 PolarHBondContact O-N 2.77Å; E610-R613 IonicContact OE1-CZ 3.65Å; E610-R613 IonicContact OE1-NE 3.35Å; E610-R613 PolarHBondContact OE1-NE 3.2Å; E610-R613 IonicContact OE1-NH2 2.73Å; E610-R613 PolarHBondContact OE1-NH2 2.94Å; E610-R613 IonicContact OE2-CZ 2.67Å; E610-R613 IonicContact OE2-NE 2.78Å; E610-R613 PolarHBondContact OE2-NE 3.49Å; E610-R613 IonicContact OE2-NH2 3.41Å; K611-R613 PolarHBondContact O-N 3.26Å; R613-A616 WeakPolarHBondContact O-CB 3.45Å; R613-A616 PolarHBondContact O-N 2.98Å; R613-K617 PolarHBondContact O-N 2.89Å; R613-D664 IonicContact CZ-OD1 3.49Å; R613-D664 IonicContact NH1-OD1 2.86Å; R613-Q665 WeakPolarHBondContact CD-O 3.45Å; R613-Q665 PolarHBondContact NH1-O 3.04Å; R613-K667 HydrophobicContact CB-CB 4.33Å; R613-K667 HydrophobicContact CG-CB 4.33Å; R613-Y670 HydrophobicContact CG-CE2 4.27Å
614N95.4Very high96.5Very high55 Ų5555.6 Ų55.629%0.29427%0.27SS..Hα-helixtrans-69-43.3178.1-68.4-59.4000111.8E610 K611 A616 K617 N618E610-N614 PolarHBondContact O-N 3.49Å; E610-N614 PolarHBondContact O-ND2 3.21Å; E610-N614 PolarHBondContact OE1-ND2 3.27Å; K611-N614 PolarHBondContact O-N 3.02Å; K611-N614 VanDerWaalsContact O-N 3.14Å; N614-A616 PolarHBondContact O-N 2.85Å; N614-K617 WeakPolarHBondContact O-CB 3.31Å; N614-K617 PolarHBondContact O-N 3.24Å; N614-K617 VanDerWaalsContact O-N 3.08Å; N614-N618 PolarHBondContact O-N 3.44Å; N614-N618 PolarHBondContact O-OD1 3.18Å; N614-N618 VanDerWaalsContact O-OD1 3.05Å
615D96.1Very high96.3Very high58 Ų5857.4 Ų57.431%0.3127%0.273SS..Hα-helixtrans-53-42.7170.9-69-19.4000109.9K611 N618 N619K611-D615 VanDerWaalsContact NZ-CG 3.26Å; K611-D615 IonicContact NZ-OD1 2.67Å; K611-D615 PolarHBondContact NZ-OD1 2.92Å; K611-D615 IonicContact NZ-OD2 2.78Å; K611-D615 PolarHBondContact NZ-OD2 3.28Å; K611-D615 WeakPolarHBondContact O-CB 3.35Å; K611-D615 VanDerWaalsContact O-CG 3.26Å; K611-D615 PolarHBondContact O-N 3.22Å; D615-N618 PolarHBondContact O-N 2.85Å; D615-N619 PolarHBondContact O-N 3.3Å; D615-N619 PolarHBondContact O-ND2 3.24Å
616A97.3Very high96.2Very high9 Ų957 Ų577%0.07427%0.27CS..Hα-helixtrans-67.3-37.917700000113.7E612 R613 N614 K667 Y670 I671E612-A616 VanDerWaalsContact O-CB 3.3Å; E612-A616 WeakPolarHBondContact O-CB 3.44Å; E612-A616 PolarHBondContact O-N 2.97Å; R613-A616 WeakPolarHBondContact O-CB 3.45Å; R613-A616 PolarHBondContact O-N 2.98Å; N614-A616 PolarHBondContact O-N 2.85Å; A616-K667 HydrophobicContact CB-CG 3.94Å; A616-Y670 HydrophobicContact CB-CD2 4.46Å; A616-I671 HydrophobicContact CB-CG1 4.48Å
617K97Very high96.1Very high26 Ų2654.4 Ų54.411%0.11326%0.258CS..Hα-helixtrans-61.1-50.8172.2-173.1-179.7-178178.50111R613 N614 N619 V620 E621 L658 E663 Y670R613-K617 PolarHBondContact O-N 2.89Å; N614-K617 WeakPolarHBondContact O-CB 3.31Å; N614-K617 PolarHBondContact O-N 3.24Å; N614-K617 VanDerWaalsContact O-N 3.08Å; K617-N619 VanDerWaalsContact C-N 3.26Å; K617-N619 PolarHBondContact O-N 2.87Å; K617-V620 WeakPolarHBondContact O-CB 3.48Å; K617-V620 PolarHBondContact O-N 3.16Å; K617-E621 PolarHBondContact O-N 3.4Å; K617-L658 WeakPolarHBondContact CE-O 3.21Å; K617-L658 HydrophobicContact CG-CD2 3.85Å; K617-L658 PolarHBondContact NZ-O 2.76Å; K617-E663 PolarHBondContact NZ-O 3.21Å; K617-Y670 HydrophobicContact CB-CD1 4.19Å; K617-Y670 HydrophobicContact CB-CD2 3.99Å; K617-Y670 HydrophobicContact CB-CE1 4.03Å; K617-Y670 HydrophobicContact CB-CE2 3.81Å; K617-Y670 HydrophobicContact CB-CG 4.18Å; K617-Y670 HydrophobicContact CD-CE1 4.25Å; K617-Y670 HydrophobicContact CG-CD1 4.2Å; K617-Y670 HydrophobicContact CG-CE1 3.74Å; K617-Y670 HydrophobicContact CG-CE2 4.31Å
618N96.4Very high95.9Very high81 Ų8157 Ų5743%0.43327%0.266SS..Hα-helixtrans-59.5-36.9-178.9-61.86.8000111.8N614 D615 V620 E621 E622N614-N618 PolarHBondContact O-N 3.44Å; N614-N618 PolarHBondContact O-OD1 3.18Å; N614-N618 VanDerWaalsContact O-OD1 3.05Å; D615-N618 PolarHBondContact O-N 2.85Å; N618-V620 PolarHBondContact O-N 3.14Å; N618-E621 PolarHBondContact O-N 3.42Å; N618-E622 WeakPolarHBondContact O-CB 3.43Å; N618-E622 PolarHBondContact O-N 2.7Å
619N97.3Very high95.7Very high78 Ų7857.6 Ų57.642%0.41728%0.275SS..Hα-helixtrans-64.1-22.4174.5-78.6-67000113.9D615 K617 Y623 L674D615-N619 PolarHBondContact O-N 3.3Å; D615-N619 PolarHBondContact O-ND2 3.24Å; K617-N619 VanDerWaalsContact C-N 3.26Å; K617-N619 PolarHBondContact O-N 2.87Å; N619-Y623 WeakPolarHBondContact O-CB 3.4Å; N619-L674 HydrophobicContact CB-CD2 3.92Å; N619-L674 WeakPolarHBondContact O-CD1 3.31Å
620V97.3Very high95.6Very high0 Ų055.7 Ų55.70%026%0.263CS..Hα-helixtrans-79.4-48.4171-172.40000109.7K617 N618 Y623 V624 T654 L658 Y670 L674 L677K617-V620 WeakPolarHBondContact O-CB 3.48Å; K617-V620 PolarHBondContact O-N 3.16Å; N618-V620 PolarHBondContact O-N 3.14Å; V620-Y623 PolarHBondContact O-N 3.4Å; V620-V624 HydrophobicContact CG1-CG2 4.32Å; V620-V624 WeakPolarHBondContact O-CB 3.39Å; V620-V624 VanDerWaalsContact O-CG2 3.31Å; V620-V624 WeakPolarHBondContact O-CG2 3.47Å; V620-V624 PolarHBondContact O-N 3.02Å; V620-T654 HydrophobicContact CG1-CG2 3.9Å; V620-L658 HydrophobicContact CB-CD1 4.3Å; V620-L658 HydrophobicContact CB-CD2 4.3Å; V620-L658 HydrophobicContact CG1-CD1 4.02Å; V620-L658 HydrophobicContact CG1-CD2 4.37Å; V620-Y670 HydrophobicContact CG2-CD1 4.39Å; V620-Y670 VanDerWaalsContact CG2-O 3.28Å; V620-Y670 WeakPolarHBondContact CG2-O 3.43Å; V620-L674 HydrophobicContact CG2-CB 4.21Å; V620-L677 HydrophobicContact CG1-CD1 4.35Å
621E96.1Very high95.4Very high52 Ų5254.9 Ų54.924%0.24326%0.259CS..Hα-helixtrans-58.6-48.6-179.5-169.4170.6-157.700111.9K617 N618 Y623 V624 Y625 L658 Y659K617-E621 PolarHBondContact O-N 3.4Å; N618-E621 PolarHBondContact O-N 3.42Å; E621-Y623 PolarHBondContact O-N 2.8Å; E621-V624 PolarHBondContact O-N 3.26Å; E621-Y625 HydrophobicContact CG-CD2 4.08Å; E621-Y625 HydrophobicContact CG-CE2 3.73Å; E621-Y625 VanDerWaalsContact O-CD2 3.23Å; E621-Y625 WeakPolarHBondContact O-CD2 3.37Å; E621-Y625 PolarHBondContact O-N 2.99Å; E621-L658 HydrophobicContact CB-CD1 4.01Å; E621-Y659 PolarHBondContact OE1-OH 3.45Å
622E97Very high95Very high135 Ų13553.9 Ų53.963%0.63126%0.26SS*.Hα-helixtrans-59-45.9175-176.9176-161.200111.9N618 V624 Y625 E626N618-E622 WeakPolarHBondContact O-CB 3.43Å; N618-E622 PolarHBondContact O-N 2.7Å; E622-V624 VanDerWaalsContact C-N 3.34Å; E622-V624 PolarHBondContact O-N 3.36Å; E622-Y625 PolarHBondContact O-N 3.02Å; E622-E626 VanDerWaalsContact O-CB 3.23Å; E622-E626 WeakPolarHBondContact O-CB 3.34Å; E622-E626 PolarHBondContact O-N 3.1Å
623Y97.3Very high94.8Very high14 Ų1453 Ų536%0.05527%0.267CS..Hα-helixtrans-68-33.2179.2-172.4-105.9000112.8N619 V620 E621 M627 L674 L677 K678N619-Y623 WeakPolarHBondContact O-CB 3.4Å; V620-Y623 PolarHBondContact O-N 3.4Å; E621-Y623 PolarHBondContact O-N 2.8Å; Y623-M627 HydrophobicContact CD1-CG 4.15Å; Y623-M627 HydrophobicContact CD2-CG 3.96Å; Y623-M627 HydrophobicContact CE1-CG 3.71Å; Y623-M627 HydrophobicContact CE2-CG 3.49Å; Y623-M627 VanDerWaalsContact CE2-CG 3.49Å; Y623-M627 HydrophobicContact CE2-SD 3.81Å; Y623-M627 HydrophobicContact CG-CG 4.26Å; Y623-M627 VanDerWaalsContact O-CB 3.31Å; Y623-M627 WeakPolarHBondContact O-CB 3.29Å; Y623-M627 VanDerWaalsContact O-CG 3.29Å; Y623-M627 WeakPolarHBondContact O-CG 3.48Å; Y623-M627 PolarHBondContact O-N 2.82Å; Y623-L674 HydrophobicContact CD1-CD1 3.73Å; Y623-L674 HydrophobicContact CD2-CD1 4.49Å; Y623-L674 HydrophobicContact CG-CD1 3.66Å; Y623-L677 HydrophobicContact CD1-CB 3.96Å; Y623-L677 HydrophobicContact CD1-CD1 4.22Å; Y623-L677 HydrophobicContact CE1-CB 3.7Å; Y623-K678 HydrophobicContact CD1-CG 4.28Å; Y623-K678 HydrophobicContact CD2-CG 4.42Å; Y623-K678 HydrophobicContact CE1-CG 3.67Å; Y623-K678 HydrophobicContact CE2-CD 4.38Å; Y623-K678 HydrophobicContact CE2-CG 3.83Å; Y623-K678 VanDerWaalsContact CZ-CG 3.43Å
624V96.1Very high94.5Very high0 Ų054.2 Ų54.20%028%0.279CS..Hα-helixtrans-64.6-50174.9164.90000110.3V620 E621 E622 R628 L651 T654 E655 L677V620-V624 HydrophobicContact CG1-CG2 4.32Å; V620-V624 WeakPolarHBondContact O-CB 3.39Å; V620-V624 VanDerWaalsContact O-CG2 3.31Å; V620-V624 WeakPolarHBondContact O-CG2 3.47Å; V620-V624 PolarHBondContact O-N 3.02Å; E621-V624 PolarHBondContact O-N 3.26Å; E622-V624 VanDerWaalsContact C-N 3.34Å; E622-V624 PolarHBondContact O-N 3.36Å; V624-R628 WeakPolarHBondContact O-CB 3.09Å; V624-R628 PolarHBondContact O-N 3.49Å; V624-L651 HydrophobicContact CG1-CB 4.42Å; V624-L651 HydrophobicContact CG2-CD2 4.13Å; V624-T654 HydrophobicContact CG2-CG2 4.19Å; V624-E655 HydrophobicContact CG1-CB 4Å; V624-E655 HydrophobicContact CG1-CG 4.5Å; V624-L677 HydrophobicContact CG2-CD1 3.67Å
625Y93.9Very high94.3Very high95 Ų9551.6 Ų51.637%0.37327%0.265SS..Hα-helixtrans-66-44.6177.4-71.8-55.1000112.9E621 E622 M627 R628 D629 E655 Y659E621-Y625 HydrophobicContact CG-CD2 4.08Å; E621-Y625 HydrophobicContact CG-CE2 3.73Å; E621-Y625 VanDerWaalsContact O-CD2 3.23Å; E621-Y625 WeakPolarHBondContact O-CD2 3.37Å; E621-Y625 PolarHBondContact O-N 2.99Å; E622-Y625 PolarHBondContact O-N 3.02Å; Y625-M627 PolarHBondContact O-N 3.14Å; Y625-R628 PolarHBondContact O-N 2.87Å; Y625-D629 PolarHBondContact O-N 2.9Å; Y625-D629 VanDerWaalsContact O-N 3.11Å; Y625-E655 HydrophobicContact CE1-CG 4.48Å; Y625-E655 WeakPolarHBondContact CE1-OE1 3.32Å; Y625-E655 PolarHBondContact OH-OE1 2.67Å; Y625-Y659 PolarHBondContact OH-OH 2.81Å
626E95Very high94.1Very high89 Ų8953.1 Ų53.142%0.41627%0.27SS..Hα-helixtrans-58.8-47.2178.2-173.7-167.5-162.700111.7E622 K630E622-E626 VanDerWaalsContact O-CB 3.23Å; E622-E626 WeakPolarHBondContact O-CB 3.34Å; E622-E626 PolarHBondContact O-N 3.1Å; E626-K630 VanDerWaalsContact CD-NZ 3.31Å; E626-K630 HydrophobicContact CG-CD 4.11Å; E626-K630 WeakPolarHBondContact O-CB 3.32Å; E626-K630 VanDerWaalsContact O-CG 3.26Å; E626-K630 WeakPolarHBondContact O-CG 3.28Å; E626-K630 PolarHBondContact O-N 3.44Å; E626-K630 VanDerWaalsContact O-N 3.12Å; E626-K630 WeakPolarHBondContact OE1-CE 3.36Å; E626-K630 IonicContact OE1-NZ 2.82Å; E626-K630 PolarHBondContact OE1-NZ 2.85Å
627M94.4Very high93.8Very high2 Ų259.5 Ų59.51%0.0130%0.297CS..Hα-helixtrans-72.8-35.1-179.4-68.6-58.1-60.400112.4Y623 Y625 K630 L631 L635 F647 L651Y623-M627 HydrophobicContact CD1-CG 4.15Å; Y623-M627 HydrophobicContact CD2-CG 3.96Å; Y623-M627 HydrophobicContact CE1-CG 3.71Å; Y623-M627 HydrophobicContact CE2-CG 3.49Å; Y623-M627 VanDerWaalsContact CE2-CG 3.49Å; Y623-M627 HydrophobicContact CE2-SD 3.81Å; Y623-M627 HydrophobicContact CG-CG 4.26Å; Y623-M627 VanDerWaalsContact O-CB 3.31Å; Y623-M627 WeakPolarHBondContact O-CB 3.29Å; Y623-M627 VanDerWaalsContact O-CG 3.29Å; Y623-M627 WeakPolarHBondContact O-CG 3.48Å; Y623-M627 PolarHBondContact O-N 2.82Å; Y625-M627 PolarHBondContact O-N 3.14Å; M627-K630 PolarHBondContact O-N 3.27Å; M627-L631 WeakPolarHBondContact O-CB 3.44Å; M627-L631 WeakPolarHBondContact O-CD1 3.49Å; M627-L631 WeakPolarHBondContact O-CG 3.49Å; M627-L631 PolarHBondContact O-N 3.31Å; M627-L635 HydrophobicContact CE-CD1 3.59Å; M627-L635 HydrophobicContact SD-CD1 4.33Å; M627-F647 HydrophobicContact CE-CE1 3.94Å; M627-L651 HydrophobicContact CB-CD1 3.88Å; M627-L651 HydrophobicContact CB-CD2 4.42Å
628R92.3Very high93.5Very high83 Ų8359 Ų5931%0.31329%0.294SS..Hα-helixtrans-64.2-40.6178.7-173.4176.4-175.2-158.9-2.3112.1V624 Y625 N632 E652 E655V624-R628 WeakPolarHBondContact O-CB 3.09Å; V624-R628 PolarHBondContact O-N 3.49Å; Y625-R628 PolarHBondContact O-N 2.87Å; R628-N632 PolarHBondContact O-ND2 3.11Å; R628-E652 IonicContact CZ-OE1 3.43Å; R628-E652 IonicContact NE-OE1 3.38Å; R628-E652 PolarHBondContact NE-OE1 2.86Å; R628-E652 IonicContact NH2-OE1 2.83Å; R628-E652 PolarHBondContact NH2-OE1 3.17Å; R628-E655 IonicContact CZ-OE2 3.68Å; R628-E655 IonicContact NH1-OE1 2.64Å; R628-E655 IonicContact NH1-OE2 2.67Å; R628-E655 PolarHBondContact NH1-OE2 3.4Å
629D92.9Very high93.3Very high125 Ų12555.7 Ų55.767%0.66828%0.277SS*.Hα-helixtrans-64.5-56170.8178.374.4000110.8Y625 L631 N632 G633Y625-D629 PolarHBondContact O-N 2.9Å; Y625-D629 VanDerWaalsContact O-N 3.11Å; D629-L631 VanDerWaalsContact C-N 3.34Å; D629-L631 PolarHBondContact O-N 3.26Å; D629-N632 CarbonylContact O-C 3.6Å; D629-N632 PolarHBondContact O-N 3.16Å; D629-G633 PolarHBondContact O-N 3.45Å
630K94.1Very high93Very high38 Ų3854.9 Ų54.917%0.16527%0.273CS..Hα-helixtrans-56.2-40.4-176.6-77.8-178-175.8176.60114E626 M627 N632 G633 S634 L635 H685E626-K630 VanDerWaalsContact CD-NZ 3.31Å; E626-K630 HydrophobicContact CG-CD 4.11Å; E626-K630 WeakPolarHBondContact O-CB 3.32Å; E626-K630 VanDerWaalsContact O-CG 3.26Å; E626-K630 WeakPolarHBondContact O-CG 3.28Å; E626-K630 PolarHBondContact O-N 3.44Å; E626-K630 VanDerWaalsContact O-N 3.12Å; E626-K630 WeakPolarHBondContact OE1-CE 3.36Å; E626-K630 IonicContact OE1-NZ 2.82Å; E626-K630 PolarHBondContact OE1-NZ 2.85Å; M627-K630 PolarHBondContact O-N 3.27Å; K630-N632 PolarHBondContact O-N 3.47Å; K630-G633 CarbonylContact O-C 3.58Å; K630-G633 PolarHBondContact O-N 3.29Å; K630-S634 PolarHBondContact O-N 2.75Å; K630-L635 HydrophobicContact CB-CB 4.49Å; K630-L635 HydrophobicContact CB-CD1 3.74Å; K630-L635 HydrophobicContact CB-CG 3.89Å; K630-L635 HydrophobicContact CD-CD1 4.21Å; K630-L635 WeakPolarHBondContact O-CB 3.4Å; K630-L635 PolarHBondContact O-N 2.99Å; K630-H685 PolarHBondContact NZ-NE2 2.96Å
631L91.4Very high92.6Very high0 Ų061.1 Ų61.10%030%0.302CS..Hα-helixtrans-64.4-25.8179.2-74.8165.7000113.7M627 D629 E636 V639 F647 L651 I684M627-L631 WeakPolarHBondContact O-CB 3.44Å; M627-L631 WeakPolarHBondContact O-CD1 3.49Å; M627-L631 WeakPolarHBondContact O-CG 3.49Å; M627-L631 PolarHBondContact O-N 3.31Å; D629-L631 VanDerWaalsContact C-N 3.34Å; D629-L631 PolarHBondContact O-N 3.26Å; L631-E636 WeakPolarHBondContact O-CA 3.32Å; L631-V639 HydrophobicContact CD2-CG1 4.12Å; L631-F647 HydrophobicContact CD1-CD1 3.54Å; L631-F647 HydrophobicContact CD1-CE1 3.85Å; L631-F647 HydrophobicContact CD1-CG 4.35Å; L631-F647 HydrophobicContact CD2-CD1 4.09Å; L631-F647 HydrophobicContact CD2-CE1 4.5Å; L631-F647 HydrophobicContact CG-CD1 4.4Å; L631-L651 HydrophobicContact CD1-CD1 3.52Å; L631-I684 HydrophobicContact CD2-CD1 4.1Å
632N86.3Confident92.4Very high105 Ų10562 Ų6256%0.56132%0.318SS*.THydrogen-bonded Turntrans-97.85.7175.5-64.6-70.4000112.4R628 D629 K630R628-N632 PolarHBondContact O-ND2 3.11Å; D629-N632 CarbonylContact O-C 3.6Å; D629-N632 PolarHBondContact O-N 3.16Å; K630-N632 PolarHBondContact O-N 3.47Å
633G90.1Very high92.1Very high41 Ų4160.1 Ų60.142%0.42331%0.312SS..THydrogen-bonded Turntrans-136.2-109-178.600000112.2D629 K630 L635 E636D629-G633 PolarHBondContact O-N 3.45Å; K630-G633 CarbonylContact O-C 3.58Å; K630-G633 PolarHBondContact O-N 3.29Å; G633-L635 VanDerWaalsContact C-N 3.31Å; G633-L635 PolarHBondContact O-N 3.09Å; G633-E636 WeakPolarHBondContact O-CB 3.07Å; G633-E636 PolarHBondContact O-N 3.3Å
634S90.7Very high91.9Very high52 Ų5261.3 Ų61.336%0.36432%0.317SS..THydrogen-bonded Turntrans-62-31.9-171.753.40000114.7K630 F638K630-S634 PolarHBondContact O-N 2.75Å; S634-F638 WeakPolarHBondContact O-CE2 3.14Å
635L92Very high91.7Very high0 Ų065 Ų650%034%0.337CS..THydrogen-bonded Turntrans-89.5-8.4-179.2-61.7-177.1000114.1M627 K630 G633 K637 F638 I684 H685 Y688M627-L635 HydrophobicContact CE-CD1 3.59Å; M627-L635 HydrophobicContact SD-CD1 4.33Å; K630-L635 HydrophobicContact CB-CB 4.49Å; K630-L635 HydrophobicContact CB-CD1 3.74Å; K630-L635 HydrophobicContact CB-CG 3.89Å; K630-L635 HydrophobicContact CD-CD1 4.21Å; K630-L635 WeakPolarHBondContact O-CB 3.4Å; K630-L635 PolarHBondContact O-N 2.99Å; G633-L635 VanDerWaalsContact C-N 3.31Å; G633-L635 PolarHBondContact O-N 3.09Å; L635-K637 PolarHBondContact O-N 2.88Å; L635-F638 PolarHBondContact O-N 3.2Å; L635-I684 HydrophobicContact CB-CG2 4Å; L635-I684 HydrophobicContact CD1-CG2 4.24Å; L635-I684 HydrophobicContact CG-CG2 4.48Å; L635-H685 HydrophobicContact CD1-CB 4.48Å; L635-Y688 HydrophobicContact CD2-CD1 3.7Å; L635-Y688 HydrophobicContact CD2-CG 3.6Å
636E90.8Very high91.7Very high90 Ų9063.5 Ų63.542%0.42134%0.343SS..G310 helixtrans-52.5-39.4-171.8-163.4-158-171.600112.6L631 G633 F638 R644L631-E636 WeakPolarHBondContact O-CA 3.32Å; G633-E636 WeakPolarHBondContact O-CB 3.07Å; G633-E636 PolarHBondContact O-N 3.3Å; E636-F638 VanDerWaalsContact C-N 3.29Å; E636-F638 PolarHBondContact O-N 3.21Å; E636-R644 IonicContact OE1-NH1 2.77Å; E636-R644 PolarHBondContact OE1-NH1 3.16Å
637K90.8Very high91.8Very high143 Ų14359.4 Ų59.462%0.62232%0.324SS*.G310 helixtrans-77.8-9.7-176.3-61.2171.3-173.51680114.1L635 L756L635-K637 PolarHBondContact O-N 2.88Å; K637-L756 HydrophobicContact CB-CD1 4.22Å; K637-L756 VanDerWaalsContact O-CB 3.27Å; K637-L756 WeakPolarHBondContact O-CB 3.22Å
638F92Very high91.8Very high15 Ų1560.1 Ų60.17%0.06633%0.33CS..G310 helixtrans-107.43.9-171.1-59-80000113.4S634 L635 E636 I684 K687 Y688 A691 L756S634-F638 WeakPolarHBondContact O-CE2 3.14Å; L635-F638 PolarHBondContact O-N 3.2Å; E636-F638 VanDerWaalsContact C-N 3.29Å; E636-F638 PolarHBondContact O-N 3.21Å; F638-I684 HydrophobicContact CB-CG2 4.18Å; F638-K687 HydrophobicContact CB-CB 4.23Å; F638-K687 HydrophobicContact CD1-CB 4.19Å; F638-Y688 HydrophobicContact CD2-CD2 4.16Å; F638-Y688 HydrophobicContact CD2-CG 4.43Å; F638-Y688 AromaticContact CE2-CD2 3.61Å; F638-Y688 HydrophobicContact CE2-CD2 3.61Å; F638-Y688 HydrophobicContact CE2-CG 4.3Å; F638-Y688 HydrophobicContact CZ-CD2 4.02Å; F638-A691 HydrophobicContact CD1-CB 4.42Å; F638-A691 HydrophobicContact CE1-CB 3.4Å; F638-A691 HydrophobicContact CZ-CB 3.85Å; F638-L756 HydrophobicContact CD1-CB 3.95Å; F638-L756 HydrophobicContact CE1-CB 3.99Å; F638-L756 HydrophobicContact CE1-CD1 4.08Å; F638-L756 HydrophobicContact CE1-CD2 4.12Å; F638-L756 HydrophobicContact CE1-CG 4.28Å; F638-L756 HydrophobicContact CZ-CD1 4.28Å
639V91.7Very high91.9Very high12 Ų1260.9 Ų60.97%0.07334%0.339CS..SBendtrans-134.4145.3174.759.20000108.7L631 D643 R644 I684 T757L631-V639 HydrophobicContact CD2-CG1 4.12Å; V639-D643 HydrophobicContact CG2-CB 3.73Å; V639-R644 HydrophobicContact CB-CB 4.5Å; V639-R644 HydrophobicContact CG1-CB 3.75Å; V639-R644 HydrophobicContact CG1-CG 3.99Å; V639-R644 HydrophobicContact CG2-CB 3.99Å; V639-I684 HydrophobicContact CB-CD1 3.94Å; V639-I684 HydrophobicContact CB-CG1 4.12Å; V639-I684 HydrophobicContact CB-CG2 3.94Å; V639-I684 HydrophobicContact CG1-CG2 4.28Å; V639-I684 HydrophobicContact CG2-CD1 3.74Å; V639-I684 HydrophobicContact CG2-CG1 4.25Å; V639-T757 WeakPolarHBondContact O-CG2 3.48Å
640N91.4Very high92.1Very high61 Ų6157.5 Ų57.533%0.32632%0.319SS..  trans-79.7159.917467.173000110.4A642 D643 R644 T757N640-A642 VanDerWaalsContact C-N 3.29Å; N640-A642 PolarHBondContact O-N 3.22Å; N640-A642 PolarHBondContact OD1-N 3.25Å; N640-D643 PolarHBondContact ND2-OD2 3.22Å; N640-D643 PolarHBondContact O-N 3.23Å; N640-D643 PolarHBondContact OD1-N 2.86Å; N640-R644 VanDerWaalsContact O-CB 3.27Å; N640-R644 WeakPolarHBondContact O-CB 3.32Å; N640-R644 PolarHBondContact O-N 3.03Å; N640-T757 HydrophobicContact CB-CG2 4.46Å
641E89.3Confident92.2Very high132 Ų13255.7 Ų55.762%0.61731%0.311SS*.Hα-helixtrans-57.7-37.2-174.2-178.6170.6-158.600113.8N645E641-N645 WeakPolarHBondContact CG-ND2 3.29Å; E641-N645 VanDerWaalsContact O-CB 3.28Å; E641-N645 WeakPolarHBondContact O-CB 3.32Å; E641-N645 PolarHBondContact O-N 3.38Å; E641-N645 PolarHBondContact O-ND2 3.27Å; E641-N645 PolarHBondContact O-OD1 3.08Å
642A91.1Very high92.4Very high69 Ų6959.5 Ų59.557%0.5733%0.328SS*.Hα-helixtrans-68.7-49.7-179.800000111.8N640 R644 N645 A646N640-A642 VanDerWaalsContact C-N 3.29Å; N640-A642 PolarHBondContact O-N 3.22Å; N640-A642 PolarHBondContact OD1-N 3.25Å; A642-R644 VanDerWaalsContact C-N 3.32Å; A642-R644 PolarHBondContact O-N 3.48Å; A642-N645 PolarHBondContact O-N 3.09Å; A642-A646 VanDerWaalsContact O-CB 3.3Å; A642-A646 WeakPolarHBondContact O-CB 3.34Å; A642-A646 PolarHBondContact O-N 2.9Å
643D91.1Very high92.8Very high97 Ų9758.9 Ų58.952%0.51933%0.325SS..Hα-helixtrans-65.9-35.4177.3-70.5-24.3000111.7V639 N640 F647V639-D643 HydrophobicContact CG2-CB 3.73Å; N640-D643 PolarHBondContact ND2-OD2 3.22Å; N640-D643 PolarHBondContact O-N 3.23Å; N640-D643 PolarHBondContact OD1-N 2.86Å; D643-F647 VanDerWaalsContact O-CB 3.3Å; D643-F647 WeakPolarHBondContact O-CB 3.5Å; D643-F647 PolarHBondContact O-N 2.89Å
644R92.1Very high93.1Very high39 Ų3957.2 Ų57.215%0.14731%0.307CS..Hα-helixtrans-61.3-55174.5-175.4-174.366.7-176.1-1.5110.3E636 V639 N640 A642 A646 F647 S648E636-R644 IonicContact OE1-NH1 2.77Å; E636-R644 PolarHBondContact OE1-NH1 3.16Å; V639-R644 HydrophobicContact CB-CB 4.5Å; V639-R644 HydrophobicContact CG1-CB 3.75Å; V639-R644 HydrophobicContact CG1-CG 3.99Å; V639-R644 HydrophobicContact CG2-CB 3.99Å; N640-R644 VanDerWaalsContact O-CB 3.27Å; N640-R644 WeakPolarHBondContact O-CB 3.32Å; N640-R644 PolarHBondContact O-N 3.03Å; A642-R644 VanDerWaalsContact C-N 3.32Å; A642-R644 PolarHBondContact O-N 3.48Å; R644-A646 VanDerWaalsContact C-N 3.3Å; R644-A646 PolarHBondContact O-N 3.49Å; R644-F647 PolarHBondContact O-N 2.87Å; R644-S648 WeakPolarHBondContact O-CB 3.31Å; R644-S648 PolarHBondContact O-N 3.45Å; R644-S648 PolarHBondContact O-OG 2.86Å
645N92.8Very high93.3Very high78 Ų7856.3 Ų56.342%0.41730%0.297SS..Hα-helixtrans-65.9-36.5-175.2-62.5-3.1000110.8E641 A642 L649E641-N645 WeakPolarHBondContact CG-ND2 3.29Å; E641-N645 VanDerWaalsContact O-CB 3.28Å; E641-N645 WeakPolarHBondContact O-CB 3.32Å; E641-N645 PolarHBondContact O-N 3.38Å; E641-N645 PolarHBondContact O-ND2 3.27Å; E641-N645 PolarHBondContact O-OD1 3.08Å; A642-N645 PolarHBondContact O-N 3.09Å; N645-L649 WeakPolarHBondContact O-CB 3.09Å; N645-L649 PolarHBondContact O-N 2.68Å
646A94.4Very high93.5Very high62 Ų6259.9 Ų59.951%0.51232%0.319SS..Hα-helixtrans-66.9-38.2173.800000113.2A642 R644 K650A642-A646 VanDerWaalsContact O-CB 3.3Å; A642-A646 WeakPolarHBondContact O-CB 3.34Å; A642-A646 PolarHBondContact O-N 2.9Å; R644-A646 VanDerWaalsContact C-N 3.3Å; R644-A646 PolarHBondContact O-N 3.49Å; A646-K650 PolarHBondContact O-N 3.37Å; A646-K650 VanDerWaalsContact O-N 3.17Å
647F95.9Very high93.8Very high3 Ų358 Ų581%0.01331%0.308CS..Hα-helixtrans-75.2-40.4177-174.6-144.2000112.1M627 L631 D643 R644 L649 K650 L651 L677 I680 G681 I684M627-F647 HydrophobicContact CE-CE1 3.94Å; L631-F647 HydrophobicContact CD1-CD1 3.54Å; L631-F647 HydrophobicContact CD1-CE1 3.85Å; L631-F647 HydrophobicContact CD1-CG 4.35Å; L631-F647 HydrophobicContact CD2-CD1 4.09Å; L631-F647 HydrophobicContact CD2-CE1 4.5Å; L631-F647 HydrophobicContact CG-CD1 4.4Å; D643-F647 VanDerWaalsContact O-CB 3.3Å; D643-F647 WeakPolarHBondContact O-CB 3.5Å; D643-F647 PolarHBondContact O-N 2.89Å; R644-F647 PolarHBondContact O-N 2.87Å; F647-L649 VanDerWaalsContact C-N 3.32Å; F647-L649 PolarHBondContact O-N 3.35Å; F647-K650 PolarHBondContact O-N 2.93Å; F647-K650 VanDerWaalsContact O-N 3.11Å; F647-L651 HydrophobicContact CD1-CD1 4.47Å; F647-L651 HydrophobicContact CD2-CG 4.23Å; F647-L651 HydrophobicContact CE1-CD1 4.26Å; F647-L651 HydrophobicContact CE2-CD1 4.37Å; F647-L651 HydrophobicContact CE2-CD2 3.89Å; F647-L651 HydrophobicContact CE2-CG 4Å; F647-L651 HydrophobicContact CZ-CD1 4.2Å; F647-L651 HydrophobicContact CZ-CD2 4.03Å; F647-L651 HydrophobicContact CZ-CG 4.27Å; F647-L651 WeakPolarHBondContact O-CG 3.45Å; F647-L651 PolarHBondContact O-N 3.27Å; F647-L677 HydrophobicContact CE2-CB 4.47Å; F647-L677 HydrophobicContact CE2-CD2 4.15Å; F647-I680 HydrophobicContact CB-CG2 3.92Å; F647-I680 HydrophobicContact CD1-CG2 3.94Å; F647-I680 HydrophobicContact CD2-CB 3.87Å; F647-I680 HydrophobicContact CD2-CD1 4.12Å; F647-I680 HydrophobicContact CD2-CG2 3.6Å; F647-I680 HydrophobicContact CE1-CG2 4.38Å; F647-I680 HydrophobicContact CE2-CB 3.87Å; F647-I680 HydrophobicContact CE2-CD1 4.47Å; F647-I680 HydrophobicContact CE2-CG2 4.07Å; F647-I680 HydrophobicContact CG-CB 4.28Å; F647-I680 HydrophobicContact CG-CG2 3.54Å; F647-I680 HydrophobicContact CZ-CB 4.29Å; F647-I680 HydrophobicContact CZ-CG2 4.45Å; F647-G681 VanDerWaalsContact CE1-CA 3.44Å; F647-I684 HydrophobicContact CD1-CD1 4Å; F647-I684 HydrophobicContact CE1-CD1 4.41Å
648S94.3Very high94Very high18 Ų1851.2 Ų51.213%0.12628%0.279CS..Hα-helixtrans-56-45.8171.5-65.70000111.7R644 K650 L651 E652R644-S648 WeakPolarHBondContact O-CB 3.31Å; R644-S648 PolarHBondContact O-N 3.45Å; R644-S648 PolarHBondContact O-OG 2.86Å; S648-K650 VanDerWaalsContact C-N 3.34Å; S648-K650 PolarHBondContact O-N 3.45Å; S648-L651 WeakPolarHBondContact O-CB 3.26Å; S648-L651 PolarHBondContact O-N 2.85Å; S648-L651 VanDerWaalsContact O-N 3.12Å; S648-E652 WeakPolarHBondContact O-CG 3.17Å; S648-E652 PolarHBondContact O-N 3.19Å
649L95.4Very high94Very high98 Ų9856.4 Ų56.451%0.51330%0.298SS..Hα-helixtrans-58.7-44.7174.3-179.262.9000111.5N645 F647 L651 E652 D653N645-L649 WeakPolarHBondContact O-CB 3.09Å; N645-L649 PolarHBondContact O-N 2.68Å; F647-L649 VanDerWaalsContact C-N 3.32Å; F647-L649 PolarHBondContact O-N 3.35Å; L649-L651 VanDerWaalsContact C-N 3.28Å; L649-L651 PolarHBondContact O-N 2.93Å; L649-E652 PolarHBondContact O-N 3.42Å; L649-D653 WeakPolarHBondContact O-CB 2.83Å; L649-D653 VanDerWaalsContact O-CG 3.26Å; L649-D653 PolarHBondContact O-N 2.68Å
650K96.1Very high94.1Very high55 Ų5562.1 Ų62.124%0.23932%0.324CS..Hα-helixtrans-64.8-29.9176.9-173.5171.2-178.1178.70113.2A646 F647 S648 T654 E676 L677 I680A646-K650 PolarHBondContact O-N 3.37Å; A646-K650 VanDerWaalsContact O-N 3.17Å; F647-K650 PolarHBondContact O-N 2.93Å; F647-K650 VanDerWaalsContact O-N 3.11Å; S648-K650 VanDerWaalsContact C-N 3.34Å; S648-K650 PolarHBondContact O-N 3.45Å; K650-T654 WeakPolarHBondContact O-CB 3.42Å; K650-T654 PolarHBondContact O-N 2.86Å; K650-T654 VanDerWaalsContact O-N 3.1Å; K650-T654 PolarHBondContact O-OG1 2.93Å; K650-E676 IonicContact NZ-OE2 2.7Å; K650-E676 PolarHBondContact NZ-OE2 2.88Å; K650-L677 HydrophobicContact CD-CD2 4.2Å; K650-L677 HydrophobicContact CG-CD2 3.99Å; K650-I680 HydrophobicContact CD-CD1 4.02Å
651L96.3Very high94.1Very high0 Ų065.2 Ų65.20%034%0.341CS..Hα-helixtrans-69.3-43.9173-66.6170.9000110.6V624 M627 L631 F647 S648 L649 T654 E655 L677V624-L651 HydrophobicContact CG1-CB 4.42Å; V624-L651 HydrophobicContact CG2-CD2 4.13Å; M627-L651 HydrophobicContact CB-CD1 3.88Å; M627-L651 HydrophobicContact CB-CD2 4.42Å; L631-L651 HydrophobicContact CD1-CD1 3.52Å; F647-L651 HydrophobicContact CD1-CD1 4.47Å; F647-L651 HydrophobicContact CD2-CG 4.23Å; F647-L651 HydrophobicContact CE1-CD1 4.26Å; F647-L651 HydrophobicContact CE2-CD1 4.37Å; F647-L651 HydrophobicContact CE2-CD2 3.89Å; F647-L651 HydrophobicContact CE2-CG 4Å; F647-L651 HydrophobicContact CZ-CD1 4.2Å; F647-L651 HydrophobicContact CZ-CD2 4.03Å; F647-L651 HydrophobicContact CZ-CG 4.27Å; F647-L651 WeakPolarHBondContact O-CG 3.45Å; F647-L651 PolarHBondContact O-N 3.27Å; S648-L651 WeakPolarHBondContact O-CB 3.26Å; S648-L651 PolarHBondContact O-N 2.85Å; S648-L651 VanDerWaalsContact O-N 3.12Å; L649-L651 VanDerWaalsContact C-N 3.28Å; L649-L651 PolarHBondContact O-N 2.93Å; L651-T654 CarbonylContact O-C 3.57Å; L651-T654 PolarHBondContact O-N 3.18Å; L651-T654 VanDerWaalsContact O-N 3.12Å; L651-E655 PolarHBondContact O-N 2.94Å; L651-L677 HydrophobicContact CD2-CD1 4.01Å; L651-L677 HydrophobicContact CD2-CD2 4Å; L651-L677 HydrophobicContact CD2-CG 4.48Å
652E95.3Very high94.1Very high79 Ų7959 Ų5937%0.36931%0.312SS..Hα-helixtrans-66.8-38.6176.3-67.6179.3161.900112.5R628 S648 L649 T654 E655 T656R628-E652 IonicContact CZ-OE1 3.43Å; R628-E652 IonicContact NE-OE1 3.38Å; R628-E652 PolarHBondContact NE-OE1 2.86Å; R628-E652 IonicContact NH2-OE1 2.83Å; R628-E652 PolarHBondContact NH2-OE1 3.17Å; S648-E652 WeakPolarHBondContact O-CG 3.17Å; S648-E652 PolarHBondContact O-N 3.19Å; L649-E652 PolarHBondContact O-N 3.42Å; E652-T654 VanDerWaalsContact C-N 3.27Å; E652-T654 PolarHBondContact O-N 3.44Å; E652-E655 PolarHBondContact O-N 3.43Å; E652-T656 WeakPolarHBondContact O-CB 3.48Å; E652-T656 PolarHBondContact O-N 3.19Å; E652-T656 PolarHBondContact O-OG1 3.23Å
653D96.1Very high94.1Very high93 Ų9361.9 Ų61.950%0.49731%0.314SS..Hα-helixtrans-59.5-37.7168.9-70-27.4000111.5L649 W657L649-D653 WeakPolarHBondContact O-CB 2.83Å; L649-D653 VanDerWaalsContact O-CG 3.26Å; L649-D653 PolarHBondContact O-N 2.68Å; D653-W657 VanDerWaalsContact O-CB 3.29Å; D653-W657 WeakPolarHBondContact O-CB 3.42Å; D653-W657 PolarHBondContact O-N 2.89Å
654T96.1Very high94.1Very high5 Ų561.1 Ų61.13%0.03131%0.31CS..Hα-helixtrans-79.5-33.4-179.2-52.30000112.2V620 V624 K650 L651 E652 W657 L658 L677V620-T654 HydrophobicContact CG1-CG2 3.9Å; V624-T654 HydrophobicContact CG2-CG2 4.19Å; K650-T654 WeakPolarHBondContact O-CB 3.42Å; K650-T654 PolarHBondContact O-N 2.86Å; K650-T654 VanDerWaalsContact O-N 3.1Å; K650-T654 PolarHBondContact O-OG1 2.93Å; L651-T654 CarbonylContact O-C 3.57Å; L651-T654 PolarHBondContact O-N 3.18Å; L651-T654 VanDerWaalsContact O-N 3.12Å; E652-T654 VanDerWaalsContact C-N 3.27Å; E652-T654 PolarHBondContact O-N 3.44Å; T654-W657 HydrophobicContact CG2-CE3 4.33Å; T654-W657 PolarHBondContact O-N 2.95Å; T654-L658 WeakPolarHBondContact O-CG 3.37Å; T654-L658 PolarHBondContact O-N 2.93Å; T654-L677 HydrophobicContact CG2-CD1 4.09Å
655E94.8Very high94.2Very high34 Ų3462.4 Ų62.416%0.15932%0.317CS..Hα-helixtrans-61-48.2169.9-167.6174.5166.400110.1V624 Y625 R628 L651 E652 W657 L658 Y659V624-E655 HydrophobicContact CG1-CB 4Å; V624-E655 HydrophobicContact CG1-CG 4.5Å; Y625-E655 HydrophobicContact CE1-CG 4.48Å; Y625-E655 WeakPolarHBondContact CE1-OE1 3.32Å; Y625-E655 PolarHBondContact OH-OE1 2.67Å; R628-E655 IonicContact CZ-OE2 3.68Å; R628-E655 IonicContact NH1-OE1 2.64Å; R628-E655 IonicContact NH1-OE2 2.67Å; R628-E655 PolarHBondContact NH1-OE2 3.4Å; L651-E655 PolarHBondContact O-N 2.94Å; E652-E655 PolarHBondContact O-N 3.43Å; E655-W657 PolarHBondContact O-N 2.88Å; E655-L658 PolarHBondContact O-N 2.91Å; E655-Y659 HydrophobicContact CG-CE2 4.05Å; E655-Y659 WeakPolarHBondContact O-CD2 3.23Å
656T95.6Very high94.3Very high75 Ų7565.9 Ų65.946%0.4633%0.331SS..Hα-helixtrans-59.6-48176-53.50000110.9E652 L658 Y659 E660E652-T656 WeakPolarHBondContact O-CB 3.48Å; E652-T656 PolarHBondContact O-N 3.19Å; E652-T656 PolarHBondContact O-OG1 3.23Å; T656-L658 VanDerWaalsContact C-N 3.35Å; T656-L658 PolarHBondContact O-N 3.4Å; T656-Y659 PolarHBondContact O-N 2.8Å; T656-E660 PolarHBondContact O-N 3.07Å
657W96.5Very high94.3Very high49 Ų4966.4 Ų66.419%0.18632%0.322CS..Hα-helixtrans-58.8-40.1177176.280.6000113D653 T654 E655 Y659 E660 G662 Q665 V669 Y670 K673D653-W657 VanDerWaalsContact O-CB 3.29Å; D653-W657 WeakPolarHBondContact O-CB 3.42Å; D653-W657 PolarHBondContact O-N 2.89Å; T654-W657 HydrophobicContact CG2-CE3 4.33Å; T654-W657 PolarHBondContact O-N 2.95Å; E655-W657 PolarHBondContact O-N 2.88Å; W657-Y659 PolarHBondContact O-N 2.76Å; W657-Y659 VanDerWaalsContact O-N 3.16Å; W657-E660 CarbonylContact O-C 3.49Å; W657-E660 PolarHBondContact O-N 2.79Å; W657-E660 VanDerWaalsContact O-N 3.09Å; W657-G662 VanDerWaalsContact CE2-CA 3.4Å; W657-G662 WeakPolarHBondContact O-CA 3.39Å; W657-G662 PolarHBondContact O-N 3.03Å; W657-Q665 HydrophobicContact CH2-CG 4.33Å; W657-Q665 HydrophobicContact CZ2-CG 3.9Å; W657-V669 HydrophobicContact CH2-CG1 3.88Å; W657-V669 HydrophobicContact CZ2-CG1 3.79Å; W657-Y670 AromaticContact CH2-CD1 3.84Å; W657-Y670 HydrophobicContact CH2-CD1 3.84Å; W657-Y670 AromaticContact CH2-CE1 3.8Å; W657-Y670 HydrophobicContact CH2-CE1 3.8Å; W657-Y670 AromaticContact CZ3-CD1 3.93Å; W657-Y670 HydrophobicContact CZ3-CD1 3.93Å; W657-Y670 AromaticContact CZ3-CE1 3.95Å; W657-Y670 HydrophobicContact CZ3-CE1 3.95Å; W657-K673 HydrophobicContact CH2-CG 3.95Å; W657-K673 HydrophobicContact CZ2-CG 4.49Å; W657-K673 HydrophobicContact CZ3-CG 3.99Å
658L95.1Very high94.4Very high2 Ų271 Ų711%0.0134%0.343CS..Hα-helixtrans-61.9-21.8-179.9-79.5168.6000114.6K617 V620 E621 T654 E655 T656 E663 Y670K617-L658 WeakPolarHBondContact CE-O 3.21Å; K617-L658 HydrophobicContact CG-CD2 3.85Å; K617-L658 PolarHBondContact NZ-O 2.76Å; V620-L658 HydrophobicContact CB-CD1 4.3Å; V620-L658 HydrophobicContact CB-CD2 4.3Å; V620-L658 HydrophobicContact CG1-CD1 4.02Å; V620-L658 HydrophobicContact CG1-CD2 4.37Å; E621-L658 HydrophobicContact CB-CD1 4.01Å; T654-L658 WeakPolarHBondContact O-CG 3.37Å; T654-L658 PolarHBondContact O-N 2.93Å; E655-L658 PolarHBondContact O-N 2.91Å; T656-L658 VanDerWaalsContact C-N 3.35Å; T656-L658 PolarHBondContact O-N 3.4Å; L658-E663 WeakPolarHBondContact O-CA 3.37Å; L658-Y670 HydrophobicContact CD2-CD1 4.29Å; L658-Y670 HydrophobicContact CD2-CE1 4.08Å
659Y92.1Very high94.5Very high123 Ų12372.5 Ų72.548%0.48235%0.351SS..Hα-helixtrans-105-3.6177.3-57.8-55.9000113.8E621 Y625 E655 T656 W657E621-Y659 PolarHBondContact OE1-OH 3.45Å; Y625-Y659 PolarHBondContact OH-OH 2.81Å; E655-Y659 HydrophobicContact CG-CE2 4.05Å; E655-Y659 WeakPolarHBondContact O-CD2 3.23Å; T656-Y659 PolarHBondContact O-N 2.8Å; W657-Y659 PolarHBondContact O-N 2.76Å; W657-Y659 VanDerWaalsContact O-N 3.16Å
660E93.3Very high94.6Very high132 Ų13267.9 Ų67.962%0.61733%0.327SS*.THydrogen-bonded Turntrans-118.4-118174.9-63.4-171.415900110.4T656 W657 G662 E663T656-E660 PolarHBondContact O-N 3.07Å; W657-E660 CarbonylContact O-C 3.49Å; W657-E660 PolarHBondContact O-N 2.79Å; W657-E660 VanDerWaalsContact O-N 3.09Å; E660-G662 PolarHBondContact O-N 2.89Å; E660-E663 WeakPolarHBondContact O-CB 3.35Å; E660-E663 PolarHBondContact O-N 3.22Å
661D92.1Very high94.7Very high127 Ų12768.6 Ų68.668%0.67933%0.333SS*.THydrogen-bonded Turntrans-54-24.7-178.4-75-25.3000114.4Q665D661-Q665 WeakPolarHBondContact O-CG 3.4Å; D661-Q665 PolarHBondContact O-NE2 2.86Å
662G90.1Very high94.8Very high0 Ų072.4 Ų72.40%035%0.353CS..THydrogen-bonded Turntrans-88.6-0.2177.600000114.9W657 E660 D664 Y670W657-G662 VanDerWaalsContact CE2-CA 3.4Å; W657-G662 WeakPolarHBondContact O-CA 3.39Å; W657-G662 PolarHBondContact O-N 3.03Å; E660-G662 PolarHBondContact O-N 2.89Å; G662-D664 VanDerWaalsContact C-N 3.26Å; G662-D664 PolarHBondContact O-N 3Å; G662-Y670 VanDerWaalsContact O-CE1 3.31Å; G662-Y670 WeakPolarHBondContact O-CE1 3.32Å; G662-Y670 PolarHBondContact O-OH 3.35Å
663E90.3Very high94.8Very high131 Ų13171.2 Ų71.261%0.61235%0.347SS*.THydrogen-bonded Turntrans-56.6-46.7-179.9-172.4-175.9-159.600110.7K617 L658 E660 Y670K617-E663 PolarHBondContact NZ-O 3.21Å; L658-E663 WeakPolarHBondContact O-CA 3.37Å; E660-E663 WeakPolarHBondContact O-CB 3.35Å; E660-E663 PolarHBondContact O-N 3.22Å; E663-Y670 PolarHBondContact O-OH 2.59Å; E663-Y670 VanDerWaalsContact O-OH 3.12Å
664D90.7Very high94.9Very high81 Ų8168 Ų6843%0.43333%0.33SS..THydrogen-bonded Turntrans-128.381.3-174.4-18031.4000112.4R44 R613 G662R44-D664 IonicContact CZ-OD1 2.8Å; R44-D664 IonicContact CZ-OD2 2.67Å; R44-D664 IonicContact NH1-OD1 3.58Å; R44-D664 PolarHBondContact NH1-OD1 2.94Å; R44-D664 IonicContact NH1-OD2 3.79Å; R44-D664 IonicContact NH2-OD1 3.98Å; R44-D664 PolarHBondContact NH2-OD1 3.15Å; R44-D664 IonicContact NH2-OD2 2.81Å; R44-D664 PolarHBondContact NH2-OD2 2.79Å; R613-D664 IonicContact CZ-OD1 3.49Å; R613-D664 IonicContact NH1-OD1 2.86Å; G662-D664 VanDerWaalsContact C-N 3.26Å; G662-D664 PolarHBondContact O-N 3Å
665Q95Very high94.9Very high66 Ų6670.5 Ų70.531%0.30835%0.351SS..  trans-118.6161.6177-69.2-66.1-2300112.5R613 W657 D661 V669 Y670R613-Q665 WeakPolarHBondContact CD-O 3.45Å; R613-Q665 PolarHBondContact NH1-O 3.04Å; W657-Q665 HydrophobicContact CH2-CG 4.33Å; W657-Q665 HydrophobicContact CZ2-CG 3.9Å; D661-Q665 WeakPolarHBondContact O-CG 3.4Å; D661-Q665 PolarHBondContact O-NE2 2.86Å; Q665-V669 HydrophobicContact CB-CB 4.08Å; Q665-V669 HydrophobicContact CB-CG1 4.28Å; Q665-V669 HydrophobicContact CB-CG2 4.4Å; Q665-V669 HydrophobicContact CG-CG1 4.44Å; Q665-Y670 HydrophobicContact CB-CE1 4.09Å; Q665-Y670 HydrophobicContact CB-CE2 4.15Å; Q665-Y670 PolarHBondContact N-OH 2.92Å; Q665-Y670 VanDerWaalsContact O-CE2 3.26Å; Q665-Y670 WeakPolarHBondContact O-CE2 3.22Å
666Q94.6Very high95Very high150 Ų15072.7 Ų72.770%0.70136%0.361SS*.  trans-66.8147174.1-61.6-172.710.600110.8Q668 V669Q666-Q668 PolarHBondContact O-N 3.47Å; Q666-V669 HydrophobicContact CB-CG2 4.38Å; Q666-V669 WeakPolarHBondContact O-CB 3.49Å; Q666-V669 PolarHBondContact O-N 3.47Å
667K95.6Very high95.1Very high73 Ų7369.1 Ų69.132%0.31734%0.339SS..Hα-helixtrans-46.5-40-178-176.9-174.9176.2-167.60113.8E612 R613 A616 V669 Y670 I671E612-K667 HydrophobicContact CB-CD 4.03Å; E612-K667 IonicContact OE2-NZ 2.81Å; E612-K667 PolarHBondContact OE2-NZ 3.42Å; R613-K667 HydrophobicContact CB-CB 4.33Å; R613-K667 HydrophobicContact CG-CB 4.33Å; A616-K667 HydrophobicContact CB-CG 3.94Å; K667-V669 VanDerWaalsContact C-N 3.34Å; K667-V669 PolarHBondContact O-N 3.16Å; K667-Y670 PolarHBondContact O-N 2.8Å; K667-I671 HydrophobicContact CG-CD1 4.07Å; K667-I671 WeakPolarHBondContact O-CG1 3.16Å; K667-I671 PolarHBondContact O-N 2.89Å
668Q96.8Very high95.1Very high101 Ų10170.7 Ų70.747%0.47235%0.347SS..Hα-helixtrans-65-35.8-178.8-168.959.143.400112.7Q666 Y670 I671 D672Q666-Q668 PolarHBondContact O-N 3.47Å; Q668-Y670 VanDerWaalsContact C-N 3.32Å; Q668-Y670 PolarHBondContact O-N 3.23Å; Q668-I671 WeakPolarHBondContact O-CB 3.33Å; Q668-I671 PolarHBondContact O-N 3.2Å; Q668-I671 VanDerWaalsContact O-N 3.13Å; Q668-D672 PolarHBondContact NE2-OD1 3.42Å; Q668-D672 VanDerWaalsContact O-CG 3.23Å; Q668-D672 PolarHBondContact O-N 2.79Å
669V97.2Very high95.1Very high48 Ų4879 Ų7929%0.29138%0.383SS..Hα-helixtrans-63.3-40-179.7-1740000110.9W657 Q665 Q666 K667 D672 K673W657-V669 HydrophobicContact CH2-CG1 3.88Å; W657-V669 HydrophobicContact CZ2-CG1 3.79Å; Q665-V669 HydrophobicContact CB-CB 4.08Å; Q665-V669 HydrophobicContact CB-CG1 4.28Å; Q665-V669 HydrophobicContact CB-CG2 4.4Å; Q665-V669 HydrophobicContact CG-CG1 4.44Å; Q666-V669 HydrophobicContact CB-CG2 4.38Å; Q666-V669 WeakPolarHBondContact O-CB 3.49Å; Q666-V669 PolarHBondContact O-N 3.47Å; K667-V669 VanDerWaalsContact C-N 3.34Å; K667-V669 PolarHBondContact O-N 3.16Å; V669-D672 PolarHBondContact O-N 3.01Å; V669-K673 WeakPolarHBondContact O-CB 3.43Å; V669-K673 WeakPolarHBondContact O-CG 3.38Å; V669-K673 PolarHBondContact O-N 3.05Å
670Y97.9Very high95.2Very high1 Ų176.4 Ų76.40%0.00438%0.377CS..Hα-helixtrans-66.9-39.3174.1-59.4-55.5000112.4R613 A616 K617 V620 W657 L658 G662 E663 Q665 K667 Q668 K673 L674R613-Y670 HydrophobicContact CG-CE2 4.27Å; A616-Y670 HydrophobicContact CB-CD2 4.46Å; K617-Y670 HydrophobicContact CB-CD1 4.19Å; K617-Y670 HydrophobicContact CB-CD2 3.99Å; K617-Y670 HydrophobicContact CB-CE1 4.03Å; K617-Y670 HydrophobicContact CB-CE2 3.81Å; K617-Y670 HydrophobicContact CB-CG 4.18Å; K617-Y670 HydrophobicContact CD-CE1 4.25Å; K617-Y670 HydrophobicContact CG-CD1 4.2Å; K617-Y670 HydrophobicContact CG-CE1 3.74Å; K617-Y670 HydrophobicContact CG-CE2 4.31Å; V620-Y670 HydrophobicContact CG2-CD1 4.39Å; V620-Y670 VanDerWaalsContact CG2-O 3.28Å; V620-Y670 WeakPolarHBondContact CG2-O 3.43Å; W657-Y670 AromaticContact CH2-CD1 3.84Å; W657-Y670 HydrophobicContact CH2-CD1 3.84Å; W657-Y670 AromaticContact CH2-CE1 3.8Å; W657-Y670 HydrophobicContact CH2-CE1 3.8Å; W657-Y670 AromaticContact CZ3-CD1 3.93Å; W657-Y670 HydrophobicContact CZ3-CD1 3.93Å; W657-Y670 AromaticContact CZ3-CE1 3.95Å; W657-Y670 HydrophobicContact CZ3-CE1 3.95Å; L658-Y670 HydrophobicContact CD2-CD1 4.29Å; L658-Y670 HydrophobicContact CD2-CE1 4.08Å; G662-Y670 VanDerWaalsContact O-CE1 3.31Å; G662-Y670 WeakPolarHBondContact O-CE1 3.32Å; G662-Y670 PolarHBondContact O-OH 3.35Å; E663-Y670 PolarHBondContact O-OH 2.59Å; E663-Y670 VanDerWaalsContact O-OH 3.12Å; Q665-Y670 HydrophobicContact CB-CE1 4.09Å; Q665-Y670 HydrophobicContact CB-CE2 4.15Å; Q665-Y670 PolarHBondContact N-OH 2.92Å; Q665-Y670 VanDerWaalsContact O-CE2 3.26Å; Q665-Y670 WeakPolarHBondContact O-CE2 3.22Å; K667-Y670 PolarHBondContact O-N 2.8Å; Q668-Y670 VanDerWaalsContact C-N 3.32Å; Q668-Y670 PolarHBondContact O-N 3.23Å; Y670-K673 PolarHBondContact O-N 3.47Å; Y670-L674 WeakPolarHBondContact O-CB 3.3Å; Y670-L674 PolarHBondContact O-N 3.27Å
671I97.5Very high95.2Very high70 Ų7070.1 Ų70.136%0.35935%0.348SS..Hα-helixtrans-62.9-45.5175.5-67.7169000110.8A616 K667 Q668 L674 A675A616-I671 HydrophobicContact CB-CG1 4.48Å; K667-I671 HydrophobicContact CG-CD1 4.07Å; K667-I671 WeakPolarHBondContact O-CG1 3.16Å; K667-I671 PolarHBondContact O-N 2.89Å; Q668-I671 WeakPolarHBondContact O-CB 3.33Å; Q668-I671 PolarHBondContact O-N 3.2Å; Q668-I671 VanDerWaalsContact O-N 3.13Å; I671-L674 PolarHBondContact O-N 2.99Å; I671-A675 WeakPolarHBondContact O-CB 3.49Å; I671-A675 PolarHBondContact O-N 2.88Å
672D97.4Very high95.3Very high81 Ų8167.8 Ų67.843%0.43333%0.333SS..Hα-helixtrans-66.8-40.2179.8-64.8-20.3000111.1Q668 V669 A675 E676Q668-D672 PolarHBondContact NE2-OD1 3.42Å; Q668-D672 VanDerWaalsContact O-CG 3.23Å; Q668-D672 PolarHBondContact O-N 2.79Å; V669-D672 PolarHBondContact O-N 3.01Å; D672-A675 PolarHBondContact O-N 3.46Å; D672-E676 PolarHBondContact O-N 2.86Å
673K96.3Very high95.4Very high53 Ų5370.7 Ų70.723%0.2335%0.351CS..Hα-helixtrans-61.9-44.4172-78.4-69.3177.3-163.30112.7W657 V669 Y670 A675 E676 L677W657-K673 HydrophobicContact CH2-CG 3.95Å; W657-K673 HydrophobicContact CZ2-CG 4.49Å; W657-K673 HydrophobicContact CZ3-CG 3.99Å; V669-K673 WeakPolarHBondContact O-CB 3.43Å; V669-K673 WeakPolarHBondContact O-CG 3.38Å; V669-K673 PolarHBondContact O-N 3.05Å; Y670-K673 PolarHBondContact O-N 3.47Å; K673-A675 VanDerWaalsContact C-N 3.29Å; K673-A675 PolarHBondContact O-N 3.26Å; K673-E676 IonicContact NZ-OE1 3.76Å; K673-E676 IonicContact NZ-OE2 3.94Å; K673-E676 WeakPolarHBondContact O-CB 3.06Å; K673-E676 PolarHBondContact O-N 3.05Å; K673-L677 WeakPolarHBondContact O-CG 3.39Å; K673-L677 PolarHBondContact O-N 2.89Å
674L97.3Very high95.6Very high26 Ų2665 Ų6514%0.13633%0.325CS..Hα-helixtrans-62.5-38175.9-172.355.4000111.8N619 V620 Y623 Y670 I671 K678N619-L674 HydrophobicContact CB-CD2 3.92Å; N619-L674 WeakPolarHBondContact O-CD1 3.31Å; V620-L674 HydrophobicContact CG2-CB 4.21Å; Y623-L674 HydrophobicContact CD1-CD1 3.73Å; Y623-L674 HydrophobicContact CD2-CD1 4.49Å; Y623-L674 HydrophobicContact CG-CD1 3.66Å; Y670-L674 WeakPolarHBondContact O-CB 3.3Å; Y670-L674 PolarHBondContact O-N 3.27Å; I671-L674 PolarHBondContact O-N 2.99Å; L674-K678 HydrophobicContact CD1-CD 4.12Å; L674-K678 HydrophobicContact CD1-CG 4.39Å; L674-K678 HydrophobicContact CG-CD 4.07Å; L674-K678 WeakPolarHBondContact O-CB 3.43Å; L674-K678 WeakPolarHBondContact O-CG 3.33Å; L674-K678 PolarHBondContact O-N 2.89Å
675A97.6Very high95.6Very high57 Ų5762.8 Ų62.847%0.47131%0.312SS..Hα-helixtrans-68-40.817500000112.5I671 D672 K673 L677 K678 K679I671-A675 WeakPolarHBondContact O-CB 3.49Å; I671-A675 PolarHBondContact O-N 2.88Å; D672-A675 PolarHBondContact O-N 3.46Å; K673-A675 VanDerWaalsContact C-N 3.29Å; K673-A675 PolarHBondContact O-N 3.26Å; A675-L677 PolarHBondContact O-N 3.02Å; A675-K678 PolarHBondContact O-N 2.72Å; A675-K679 WeakPolarHBondContact O-CB 3.36Å; A675-K679 PolarHBondContact O-N 3.12Å
676E96.6Very high95.5Very high81 Ų8163 Ų6338%0.37932%0.315SS..Hα-helixtrans-57.8-44.6172.7-85.5-171.7-139.500112.4K650 D672 K673K650-E676 IonicContact NZ-OE2 2.7Å; K650-E676 PolarHBondContact NZ-OE2 2.88Å; D672-E676 PolarHBondContact O-N 2.86Å; K673-E676 IonicContact NZ-OE1 3.76Å; K673-E676 IonicContact NZ-OE2 3.94Å; K673-E676 WeakPolarHBondContact O-CB 3.06Å; K673-E676 PolarHBondContact O-N 3.05Å
677L96.9Very high95.4Very high0 Ų057.7 Ų57.70%029%0.29CS..Hα-helixtrans-71-46.2179.2-64.4179.8000111.2V620 Y623 V624 F647 K650 L651 T654 K673 A675 K679 I680 G681V620-L677 HydrophobicContact CG1-CD1 4.35Å; Y623-L677 HydrophobicContact CD1-CB 3.96Å; Y623-L677 HydrophobicContact CD1-CD1 4.22Å; Y623-L677 HydrophobicContact CE1-CB 3.7Å; V624-L677 HydrophobicContact CG2-CD1 3.67Å; F647-L677 HydrophobicContact CE2-CB 4.47Å; F647-L677 HydrophobicContact CE2-CD2 4.15Å; K650-L677 HydrophobicContact CD-CD2 4.2Å; K650-L677 HydrophobicContact CG-CD2 3.99Å; L651-L677 HydrophobicContact CD2-CD1 4.01Å; L651-L677 HydrophobicContact CD2-CD2 4Å; L651-L677 HydrophobicContact CD2-CG 4.48Å; T654-L677 HydrophobicContact CG2-CD1 4.09Å; K673-L677 WeakPolarHBondContact O-CG 3.39Å; K673-L677 PolarHBondContact O-N 2.89Å; A675-L677 PolarHBondContact O-N 3.02Å; L677-K679 PolarHBondContact O-N 2.64Å; L677-I680 PolarHBondContact O-N 2.95Å; L677-G681 PolarHBondContact O-N 3.41Å
678K96.2Very high95.2Very high81 Ų8157.1 Ų57.135%0.35229%0.286SS..Hα-helixtrans-62.3-28.9178.5-77.3178.3177174.10113Y623 L674 A675 I680 Q682Y623-K678 HydrophobicContact CD1-CG 4.28Å; Y623-K678 HydrophobicContact CD2-CG 4.42Å; Y623-K678 HydrophobicContact CE1-CG 3.67Å; Y623-K678 HydrophobicContact CE2-CD 4.38Å; Y623-K678 HydrophobicContact CE2-CG 3.83Å; Y623-K678 VanDerWaalsContact CZ-CG 3.43Å; L674-K678 HydrophobicContact CD1-CD 4.12Å; L674-K678 HydrophobicContact CD1-CG 4.39Å; L674-K678 HydrophobicContact CG-CD 4.07Å; L674-K678 WeakPolarHBondContact O-CB 3.43Å; L674-K678 WeakPolarHBondContact O-CG 3.33Å; L674-K678 PolarHBondContact O-N 2.89Å; A675-K678 PolarHBondContact O-N 2.72Å; K678-I680 PolarHBondContact O-N 3.1Å; K678-Q682 WeakPolarHBondContact O-CB 3.28Å; K678-Q682 PolarHBondContact O-N 2.82Å
679K96.1Very high94.9Very high177 Ų17756 Ų5677%0.7728%0.283SS*.Hα-helixtrans-59.5-25.4172.4-171.3176.3178.9-177.30113.6A675 L677A675-K679 WeakPolarHBondContact O-CB 3.36Å; A675-K679 PolarHBondContact O-N 3.12Å; L677-K679 PolarHBondContact O-N 2.64Å
680I94.1Very high94.7Very high69 Ų6955.3 Ų55.335%0.35428%0.277SS..Hα-helixtrans-100.1-45177.8-53.9170.9000110.6F647 K650 L677 K678 P683F647-I680 HydrophobicContact CB-CG2 3.92Å; F647-I680 HydrophobicContact CD1-CG2 3.94Å; F647-I680 HydrophobicContact CD2-CB 3.87Å; F647-I680 HydrophobicContact CD2-CD1 4.12Å; F647-I680 HydrophobicContact CD2-CG2 3.6Å; F647-I680 HydrophobicContact CE1-CG2 4.38Å; F647-I680 HydrophobicContact CE2-CB 3.87Å; F647-I680 HydrophobicContact CE2-CD1 4.47Å; F647-I680 HydrophobicContact CE2-CG2 4.07Å; F647-I680 HydrophobicContact CG-CB 4.28Å; F647-I680 HydrophobicContact CG-CG2 3.54Å; F647-I680 HydrophobicContact CZ-CB 4.29Å; F647-I680 HydrophobicContact CZ-CG2 4.45Å; K650-I680 HydrophobicContact CD-CD1 4.02Å; L677-I680 PolarHBondContact O-N 2.95Å; K678-I680 PolarHBondContact O-N 3.1Å; I680-P683 WeakPolarHBondContact O-CD 3.49Å
681G93.3Very high94.4Very high0 Ų056.2 Ų56.20%028%0.284CS..Hα-helixtrans-75.5-34.2-175.700000115.3F647 L677 I684 H685F647-G681 VanDerWaalsContact CE1-CA 3.44Å; L677-G681 PolarHBondContact O-N 3.41Å; G681-I684 PolarHBondContact O-N 2.97Å; G681-H685 PolarHBondContact O-N 2.83Å
682Q93.3Very high94.1Very high78 Ų7857.3 Ų57.336%0.36429%0.288SS..Hα-helixtrans-63.3-45.6-177.1-16870.652.300112.4K678 I684 H685 D686K678-Q682 WeakPolarHBondContact O-CB 3.28Å; K678-Q682 PolarHBondContact O-N 2.82Å; Q682-I684 PolarHBondContact O-N 3.48Å; Q682-H685 PolarHBondContact O-N 3.46Å; Q682-H685 VanDerWaalsContact O-N 3.16Å; Q682-D686 PolarHBondContact NE2-OD1 3.4Å; Q682-D686 WeakPolarHBondContact O-CB 3.17Å; Q682-D686 PolarHBondContact O-N 3.42Å
683P93.6Very high93.9Very high60 Ų6056.7 Ų56.739%0.3928%0.282SS..Hα-helixtrans-59.3-29175.2-26.536000114.9I680 K687I680-P683 WeakPolarHBondContact O-CD 3.49Å; P683-K687 WeakPolarHBondContact O-CD 3.49Å; P683-K687 VanDerWaalsContact O-CG 3.27Å; P683-K687 WeakPolarHBondContact O-CG 3.49Å; P683-K687 PolarHBondContact O-N 2.81Å
684I92.9Very high93.8Very high11 Ų1155 Ų556%0.05628%0.275CS..Hα-helixtrans-74.3-46.6175.8-56.5167.6000109.6L631 L635 F638 V639 F647 G681 Q682 D686 K687 Y688L631-I684 HydrophobicContact CD2-CD1 4.1Å; L635-I684 HydrophobicContact CB-CG2 4Å; L635-I684 HydrophobicContact CD1-CG2 4.24Å; L635-I684 HydrophobicContact CG-CG2 4.48Å; F638-I684 HydrophobicContact CB-CG2 4.18Å; V639-I684 HydrophobicContact CB-CD1 3.94Å; V639-I684 HydrophobicContact CB-CG1 4.12Å; V639-I684 HydrophobicContact CB-CG2 3.94Å; V639-I684 HydrophobicContact CG1-CG2 4.28Å; V639-I684 HydrophobicContact CG2-CD1 3.74Å; V639-I684 HydrophobicContact CG2-CG1 4.25Å; F647-I684 HydrophobicContact CD1-CD1 4Å; F647-I684 HydrophobicContact CE1-CD1 4.41Å; G681-I684 PolarHBondContact O-N 2.97Å; Q682-I684 PolarHBondContact O-N 3.48Å; I684-D686 VanDerWaalsContact C-N 3.34Å; I684-D686 PolarHBondContact O-N 2.84Å; I684-K687 PolarHBondContact O-N 3.14Å; I684-Y688 PolarHBondContact O-N 2.94Å
685H91.5Very high93.6Very high36 Ų3657.6 Ų57.617%0.16729%0.293CS..Hα-helixtrans-63.5-38.6177.3-167.6-86.9000112.4K630 L635 G681 Q682 Y688 L689K630-H685 PolarHBondContact NZ-NE2 2.96Å; L635-H685 HydrophobicContact CD1-CB 4.48Å; G681-H685 PolarHBondContact O-N 2.83Å; Q682-H685 PolarHBondContact O-N 3.46Å; Q682-H685 VanDerWaalsContact O-N 3.16Å; H685-Y688 WeakPolarHBondContact O-CB 3.43Å; H685-Y688 PolarHBondContact O-N 2.72Å; H685-L689 WeakPolarHBondContact O-CG 3.27Å; H685-L689 PolarHBondContact O-N 3.49Å
686D92Very high93.4Very high70 Ų7059.7 Ų59.737%0.37429%0.292SS..Hα-helixtrans-64.2-41.7177-70.7-9.7000111.2Q682 I684 Y688 L689 E690Q682-D686 PolarHBondContact NE2-OD1 3.4Å; Q682-D686 WeakPolarHBondContact O-CB 3.17Å; Q682-D686 PolarHBondContact O-N 3.42Å; I684-D686 VanDerWaalsContact C-N 3.34Å; I684-D686 PolarHBondContact O-N 2.84Å; D686-Y688 VanDerWaalsContact C-N 3.34Å; D686-Y688 PolarHBondContact O-N 2.85Å; D686-L689 PolarHBondContact O-N 2.85Å; D686-E690 WeakPolarHBondContact O-CB 3.45Å; D686-E690 WeakPolarHBondContact O-CG 3.37Å; D686-E690 PolarHBondContact O-N 2.85Å
687K92.5Very high93.3Very high39 Ų3956.1 Ų56.117%0.1728%0.275CS..Hα-helixtrans-61.1-40.1174.6-75.1166.9-172.6172.50112.5F638 P683 I684 A691 T757 D759F638-K687 HydrophobicContact CB-CB 4.23Å; F638-K687 HydrophobicContact CD1-CB 4.19Å; P683-K687 WeakPolarHBondContact O-CD 3.49Å; P683-K687 VanDerWaalsContact O-CG 3.27Å; P683-K687 WeakPolarHBondContact O-CG 3.49Å; P683-K687 PolarHBondContact O-N 2.81Å; I684-K687 PolarHBondContact O-N 3.14Å; K687-A691 WeakPolarHBondContact O-CB 2.97Å; K687-A691 PolarHBondContact O-N 3.27Å; K687-T757 PolarHBondContact NZ-O 3.48Å; K687-D759 WeakPolarHBondContact CE-OD1 3.39Å; K687-D759 IonicContact NZ-OD1 2.71Å
688Y92Very high93.2Very high60 Ų6056.7 Ų56.724%0.23528%0.278CS..Hα-helixtrans-63.7-52.6174.7164.1-115.3000112.1L635 F638 I684 H685 D686 E690 A691 E692L635-Y688 HydrophobicContact CD2-CD1 3.7Å; L635-Y688 HydrophobicContact CD2-CG 3.6Å; F638-Y688 HydrophobicContact CD2-CD2 4.16Å; F638-Y688 HydrophobicContact CD2-CG 4.43Å; F638-Y688 AromaticContact CE2-CD2 3.61Å; F638-Y688 HydrophobicContact CE2-CD2 3.61Å; F638-Y688 HydrophobicContact CE2-CG 4.3Å; F638-Y688 HydrophobicContact CZ-CD2 4.02Å; I684-Y688 PolarHBondContact O-N 2.94Å; H685-Y688 WeakPolarHBondContact O-CB 3.43Å; H685-Y688 PolarHBondContact O-N 2.72Å; D686-Y688 VanDerWaalsContact C-N 3.34Å; D686-Y688 PolarHBondContact O-N 2.85Å; Y688-E690 VanDerWaalsContact C-N 3.29Å; Y688-E690 PolarHBondContact O-N 3Å; Y688-A691 PolarHBondContact O-N 2.7Å; Y688-E692 HydrophobicContact CD2-CG 3.97Å; Y688-E692 HydrophobicContact CE2-CG 3.41Å; Y688-E692 VanDerWaalsContact CE2-CG 3.41Å; Y688-E692 PolarHBondContact O-N 3.12Å
689L91.5Very high93.1Very high79 Ų7959.7 Ų59.741%0.41429%0.293SS..Hα-helixtrans-57-43.8176.5-70.2176.2000111.8H685 D686 A691 E692 E693H685-L689 WeakPolarHBondContact O-CG 3.27Å; H685-L689 PolarHBondContact O-N 3.49Å; D686-L689 PolarHBondContact O-N 2.85Å; L689-A691 VanDerWaalsContact C-N 3.3Å; L689-A691 PolarHBondContact O-N 3.25Å; L689-E692 PolarHBondContact O-N 2.77Å; L689-E693 WeakPolarHBondContact O-CB 3.29Å; L689-E693 PolarHBondContact O-N 3.1Å
690E93.3Very high93Very high33 Ų3354.4 Ų54.415%0.15427%0.271CS..Hα-helixtrans-61.9-33.4174.8-93.3-74.5156.600112.7D686 Y688 R694 P760 K763 V764D686-E690 WeakPolarHBondContact O-CB 3.45Å; D686-E690 WeakPolarHBondContact O-CG 3.37Å; D686-E690 PolarHBondContact O-N 2.85Å; Y688-E690 VanDerWaalsContact C-N 3.29Å; Y688-E690 PolarHBondContact O-N 3Å; E690-R694 WeakPolarHBondContact O-CB 3.23Å; E690-R694 VanDerWaalsContact O-CZ 3.28Å; E690-R694 PolarHBondContact O-N 2.95Å; E690-R694 PolarHBondContact O-NH1 2.93Å; E690-R694 PolarHBondContact O-NH2 2.77Å; E690-R694 IonicContact OE2-CZ 2.87Å; E690-R694 IonicContact OE2-NE 2.72Å; E690-R694 IonicContact OE2-NH2 2.73Å; E690-R694 PolarHBondContact OE2-NH2 2.58Å; E690-P760 HydrophobicContact CG-CG 4.5Å; E690-K763 WeakPolarHBondContact OE1-CA 3.34Å; E690-K763 WeakPolarHBondContact OE1-CB 3.43Å; E690-K763 VanDerWaalsContact OE2-CA 3.28Å; E690-K763 WeakPolarHBondContact OE2-CA 3.34Å; E690-V764 VanDerWaalsContact CD-N 3.34Å; E690-V764 WeakPolarHBondContact OE1-CB 3.47Å; E690-V764 PolarHBondContact OE1-N 2.91Å; E690-V764 PolarHBondContact OE2-N 3.18Å
691A90.4Very high93Very high20 Ų2051.1 Ų51.117%0.16525%0.254CS..Hα-helixtrans-76.9-35.9176.100000113.6F638 K687 Y688 L689 P695F638-A691 HydrophobicContact CD1-CB 4.42Å; F638-A691 HydrophobicContact CE1-CB 3.4Å; F638-A691 HydrophobicContact CZ-CB 3.85Å; K687-A691 WeakPolarHBondContact O-CB 2.97Å; K687-A691 PolarHBondContact O-N 3.27Å; Y688-A691 PolarHBondContact O-N 2.7Å; L689-A691 VanDerWaalsContact C-N 3.3Å; L689-A691 PolarHBondContact O-N 3.25Å; A691-P695 WeakPolarHBondContact O-CD 3.31Å
692E91.3Very high93.1Very high93 Ų9351.8 Ų51.844%0.43526%0.261SS..Hα-helixtrans-70.2-39.5175.7-74.3-68134.700112.8Y688 L689 K696Y688-E692 HydrophobicContact CD2-CG 3.97Å; Y688-E692 HydrophobicContact CE2-CG 3.41Å; Y688-E692 VanDerWaalsContact CE2-CG 3.41Å; Y688-E692 PolarHBondContact O-N 3.12Å; L689-E692 PolarHBondContact O-N 2.77Å; E692-K696 VanDerWaalsContact O-CE 3.22Å; E692-K696 WeakPolarHBondContact O-CE 3.23Å
693E93.2Very high93.2Very high67 Ų6754.5 Ų54.531%0.31327%0.268SS..Hα-helixtrans-88.7-22.2-174.6-76.8-68111.900114.1L689 K696 A697 V764 K768L689-E693 WeakPolarHBondContact O-CB 3.29Å; L689-E693 PolarHBondContact O-N 3.1Å; E693-K696 PolarHBondContact O-N 2.77Å; E693-K696 WeakPolarHBondContact OE1-CD 3.41Å; E693-K696 IonicContact OE1-NZ 3.17Å; E693-K696 PolarHBondContact OE1-NZ 2.83Å; E693-A697 PolarHBondContact O-N 3.27Å; E693-V764 HydrophobicContact CB-CG1 4.23Å; E693-V764 HydrophobicContact CB-CG2 3.7Å; E693-K768 IonicContact OE2-NZ 3.27Å
694R93.9Very high93.2Very high18 Ų1852.8 Ų52.87%0.06826%0.255CS..Hα-helixtrans-65-42.2-178.2-172-172.1-55.595.720.6114.1E690 K696 A697 F698 V762 V764 I767E690-R694 WeakPolarHBondContact O-CB 3.23Å; E690-R694 VanDerWaalsContact O-CZ 3.28Å; E690-R694 PolarHBondContact O-N 2.95Å; E690-R694 PolarHBondContact O-NH1 2.93Å; E690-R694 PolarHBondContact O-NH2 2.77Å; E690-R694 IonicContact OE2-CZ 2.87Å; E690-R694 IonicContact OE2-NE 2.72Å; E690-R694 IonicContact OE2-NH2 2.73Å; E690-R694 PolarHBondContact OE2-NH2 2.58Å; R694-K696 VanDerWaalsContact C-N 3.32Å; R694-K696 PolarHBondContact O-N 3.04Å; R694-A697 PolarHBondContact O-N 3.32Å; R694-F698 HydrophobicContact CG-CD2 3.76Å; R694-F698 HydrophobicContact CG-CE2 3.73Å; R694-F698 PolarHBondContact O-N 3.24Å; R694-V762 PolarHBondContact NE-O 3.4Å; R694-V764 HydrophobicContact CB-CG2 4.03Å; R694-I767 HydrophobicContact CG-CD1 3.51Å
695P92.9Very high93.2Very high80 Ų8052.3 Ų52.352%0.51925%0.253SS..Hα-helixtrans-56.3-46.4174.5-26.435.5000112A691 A697 F698 E699A691-P695 WeakPolarHBondContact O-CD 3.31Å; P695-A697 VanDerWaalsContact C-N 3.35Å; P695-A697 PolarHBondContact O-N 2.97Å; P695-F698 PolarHBondContact O-N 3.47Å; P695-E699 WeakPolarHBondContact O-CB 3.19Å; P695-E699 PolarHBondContact O-N 2.88Å
696K94.4Very high93.3Very high102 Ų10256.1 Ų56.144%0.44327%0.271SS..Hα-helixtrans-62.9-40178.9-51.7171.9-161.3162.70111.8E692 E693 R694 E699 E700E692-K696 VanDerWaalsContact O-CE 3.22Å; E692-K696 WeakPolarHBondContact O-CE 3.23Å; E693-K696 PolarHBondContact O-N 2.77Å; E693-K696 WeakPolarHBondContact OE1-CD 3.41Å; E693-K696 IonicContact OE1-NZ 3.17Å; E693-K696 PolarHBondContact OE1-NZ 2.83Å; R694-K696 VanDerWaalsContact C-N 3.32Å; R694-K696 PolarHBondContact O-N 3.04Å; K696-E699 PolarHBondContact O-N 3.04Å; K696-E700 PolarHBondContact O-N 2.66Å; K696-E700 VanDerWaalsContact O-N 3.15Å
697A94.1Very high93.4Very high5 Ų556.3 Ų56.34%0.04127%0.27CS..Hα-helixtrans-67.1-39.1175.800000112.5E693 R694 P695 L701 V764 I767 K768E693-A697 PolarHBondContact O-N 3.27Å; R694-A697 PolarHBondContact O-N 3.32Å; P695-A697 VanDerWaalsContact C-N 3.35Å; P695-A697 PolarHBondContact O-N 2.97Å; A697-L701 PolarHBondContact O-N 2.99Å; A697-V764 HydrophobicContact CB-CG1 4.31Å; A697-I767 HydrophobicContact CB-CB 4.12Å; A697-I767 HydrophobicContact CB-CD1 4.28Å; A697-I767 HydrophobicContact CB-CG2 3.91Å; A697-I767 WeakPolarHBondContact O-CG2 3.22Å; A697-K768 HydrophobicContact CB-CG 4.39Å
698F95Very high93.5Very high12 Ų1254.5 Ų54.55%0.05326%0.262CS..Hα-helixtrans-70-36.8174.2-87.3-46.8000112.7R694 P695 L701 G702 W743 M744 K747 M748 V762 I767R694-F698 HydrophobicContact CG-CD2 3.76Å; R694-F698 HydrophobicContact CG-CE2 3.73Å; R694-F698 PolarHBondContact O-N 3.24Å; P695-F698 PolarHBondContact O-N 3.47Å; F698-L701 HydrophobicContact CD1-CD2 4.5Å; F698-L701 PolarHBondContact O-N 3.33Å; F698-G702 PolarHBondContact O-N 3.23Å; F698-W743 HydrophobicContact CE1-CZ3 4.35Å; F698-M744 HydrophobicContact CB-CE 4.14Å; F698-M744 HydrophobicContact CD1-CE 4.32Å; F698-M744 HydrophobicContact CD1-CG 3.86Å; F698-M744 HydrophobicContact CE1-CG 4.08Å; F698-M744 WeakPolarHBondContact O-CE 3.49Å; F698-K747 HydrophobicContact CZ-CB 4.14Å; F698-M748 HydrophobicContact CD2-CG 4.46Å; F698-M748 HydrophobicContact CE2-CB 4.06Å; F698-M748 HydrophobicContact CE2-CG 4.28Å; F698-M748 HydrophobicContact CZ-CB 4.03Å; F698-V762 HydrophobicContact CE2-CG1 4.24Å; F698-V762 HydrophobicContact CZ-CG1 3.76Å; F698-I767 HydrophobicContact CD1-CD1 3.82Å; F698-I767 HydrophobicContact CD1-CG1 4.25Å; F698-I767 HydrophobicContact CD1-CG2 4.06Å; F698-I767 HydrophobicContact CD2-CD1 3.87Å; F698-I767 HydrophobicContact CE1-CD1 3.71Å; F698-I767 HydrophobicContact CE1-CG1 3.96Å; F698-I767 HydrophobicContact CE1-CG2 4.48Å; F698-I767 HydrophobicContact CE2-CD1 3.76Å; F698-I767 HydrophobicContact CG-CD1 3.9Å; F698-I767 HydrophobicContact CZ-CD1 3.69Å; F698-I767 HydrophobicContact CZ-CG1 4.25Å
699E94.2Very high93.4Very high145 Ų14554 Ų5468%0.67826%0.262SS*.Hα-helixtrans-60.7-47.1175.8-175.3177.4-172.800111.2P695 K696 L701 G702 R703P695-E699 WeakPolarHBondContact O-CB 3.19Å; P695-E699 PolarHBondContact O-N 2.88Å; K696-E699 PolarHBondContact O-N 3.04Å; E699-L701 PolarHBondContact O-N 3.49Å; E699-G702 PolarHBondContact O-N 3.28Å; E699-R703 WeakPolarHBondContact O-CB 3.45Å; E699-R703 PolarHBondContact O-N 2.92Å
700E93.9Very high93.5Very high65 Ų6556.5 Ų56.530%0.30427%0.27SS..Hα-helixtrans-64.3-39.4175.8174.356.3-162.700112.6K696 R703 Q704 T771K696-E700 PolarHBondContact O-N 2.66Å; K696-E700 VanDerWaalsContact O-N 3.15Å; E700-R703 PolarHBondContact O-N 2.95Å; E700-R703 IonicContact OE1-CZ 2.77Å; E700-R703 IonicContact OE1-NE 3.21Å; E700-R703 IonicContact OE1-NH2 2.66Å; E700-R703 PolarHBondContact OE1-NH2 3.11Å; E700-R703 IonicContact OE2-CZ 3.83Å; E700-R703 IonicContact OE2-NE 2.61Å; E700-R703 PolarHBondContact OE2-NE 3.37Å; E700-R703 IonicContact OE2-NH2 2.72Å; E700-R703 PolarHBondContact OE2-NH2 2.75Å; E700-Q704 PolarHBondContact O-N 3.49Å; E700-Q704 VanDerWaalsContact O-N 3.09Å; E700-Q704 PolarHBondContact OE1-NE2 3.25Å; E700-T771 HydrophobicContact CG-CG2 4.35Å
701L94.8Very high93.3Very high0 Ų055.8 Ų55.80%027%0.267CS..Hα-helixtrans-61.6-47172.8178.158.2000111.2A697 F698 E699 R703 Q704 I705 W743 M744 I767 L774A697-L701 PolarHBondContact O-N 2.99Å; F698-L701 HydrophobicContact CD1-CD2 4.5Å; F698-L701 PolarHBondContact O-N 3.33Å; E699-L701 PolarHBondContact O-N 3.49Å; L701-R703 VanDerWaalsContact C-N 3.34Å; L701-R703 PolarHBondContact O-N 3.29Å; L701-Q704 PolarHBondContact O-N 2.9Å; L701-I705 HydrophobicContact CD1-CD1 4Å; L701-I705 HydrophobicContact CD1-CG1 4.3Å; L701-I705 HydrophobicContact CG-CD1 3.85Å; L701-I705 VanDerWaalsContact O-CG1 3.31Å; L701-I705 WeakPolarHBondContact O-CG1 3.18Å; L701-I705 PolarHBondContact O-N 3.06Å; L701-W743 HydrophobicContact CD2-CE3 4.13Å; L701-W743 HydrophobicContact CD2-CZ3 3.81Å; L701-M744 HydrophobicContact CB-SD 4.36Å; L701-M744 HydrophobicContact CD2-CB 4.08Å; L701-M744 HydrophobicContact CD2-CG 4.26Å; L701-M744 HydrophobicContact CD2-SD 4.16Å; L701-M744 HydrophobicContact CG-SD 4.01Å; L701-I767 HydrophobicContact CB-CG2 4.18Å; L701-I767 HydrophobicContact CD2-CG2 4.01Å; L701-L774 HydrophobicContact CD1-CD2 4.17Å
702G94.3Very high93.2Very high14 Ų1455 Ų5514%0.14426%0.26CS..Hα-helixtrans-61.3-40.2177.300000112.7F698 E699 I705 Q706F698-G702 PolarHBondContact O-N 3.23Å; E699-G702 PolarHBondContact O-N 3.28Å; G702-I705 PolarHBondContact O-N 3.43Å; G702-Q706 WeakPolarHBondContact O-CB 3.42Å; G702-Q706 WeakPolarHBondContact O-CG 3.44Å; G702-Q706 PolarHBondContact O-N 2.85Å
703R95.3Very high93.1Very high135 Ų13555.8 Ų55.851%0.50926%0.264SS..Hα-helixtrans-61.7-43175.6-168.2-175.269.881.25.3111.8E699 E700 L701 M707E699-R703 WeakPolarHBondContact O-CB 3.45Å; E699-R703 PolarHBondContact O-N 2.92Å; E700-R703 PolarHBondContact O-N 2.95Å; E700-R703 IonicContact OE1-CZ 2.77Å; E700-R703 IonicContact OE1-NE 3.21Å; E700-R703 IonicContact OE1-NH2 2.66Å; E700-R703 PolarHBondContact OE1-NH2 3.11Å; E700-R703 IonicContact OE2-CZ 3.83Å; E700-R703 IonicContact OE2-NE 2.61Å; E700-R703 PolarHBondContact OE2-NE 3.37Å; E700-R703 IonicContact OE2-NH2 2.72Å; E700-R703 PolarHBondContact OE2-NH2 2.75Å; L701-R703 VanDerWaalsContact C-N 3.34Å; L701-R703 PolarHBondContact O-N 3.29Å; R703-M707 WeakPolarHBondContact O-CB 3.45Å; R703-M707 PolarHBondContact O-N 3.39Å
704Q93.1Very high92.9Very high24 Ų2454.1 Ų54.111%0.11226%0.26CS..Hα-helixtrans-70.5-40.4176-67.3-161.424.800112.5E700 L701 Q706 M707 Y708 T771E700-Q704 PolarHBondContact O-N 3.49Å; E700-Q704 VanDerWaalsContact O-N 3.09Å; E700-Q704 PolarHBondContact OE1-NE2 3.25Å; L701-Q704 PolarHBondContact O-N 2.9Å; Q704-Q706 PolarHBondContact O-N 3.47Å; Q704-M707 WeakPolarHBondContact O-CB 3.41Å; Q704-M707 PolarHBondContact O-N 3.31Å; Q704-Y708 HydrophobicContact CB-CE2 4.29Å; Q704-Y708 WeakPolarHBondContact O-CD2 3.16Å; Q704-Y708 PolarHBondContact O-N 2.91Å; Q704-T771 HydrophobicContact CG-CG2 4.26Å
705I94.2Very high92.6Very high2 Ų255.2 Ų55.21%0.0126%0.264CS..Hα-helixtrans-55.8-52172.2-72.2167.3000110.2L701 G702 M707 Y708 M709 V737 A740 M741 M744 L774L701-I705 HydrophobicContact CD1-CD1 4Å; L701-I705 HydrophobicContact CD1-CG1 4.3Å; L701-I705 HydrophobicContact CG-CD1 3.85Å; L701-I705 VanDerWaalsContact O-CG1 3.31Å; L701-I705 WeakPolarHBondContact O-CG1 3.18Å; L701-I705 PolarHBondContact O-N 3.06Å; G702-I705 PolarHBondContact O-N 3.43Å; I705-M707 VanDerWaalsContact C-N 3.3Å; I705-M707 PolarHBondContact O-N 2.86Å; I705-Y708 PolarHBondContact O-N 3.41Å; I705-M709 HydrophobicContact CG2-CG 4.42Å; I705-M709 HydrophobicContact CG2-SD 4.22Å; I705-M709 WeakPolarHBondContact O-CG 3.45Å; I705-M709 PolarHBondContact O-N 2.93Å; I705-V737 HydrophobicContact CG2-CG1 4.04Å; I705-A740 HydrophobicContact CD1-CB 4.05Å; I705-A740 HydrophobicContact CG1-CB 4.18Å; I705-M741 HydrophobicContact CD1-CB 4.48Å; I705-M741 HydrophobicContact CG2-CB 4.09Å; I705-M741 HydrophobicContact CG2-CE 3.62Å; I705-M744 HydrophobicContact CD1-CB 4.39Å; I705-M744 HydrophobicContact CD1-SD 3.9Å; I705-L774 HydrophobicContact CD1-CD2 4.49Å; I705-L774 HydrophobicContact CG1-CD2 3.48Å; I705-L774 VanDerWaalsContact CG1-CD2 3.48Å
706Q93.6Very high92.3Very high116 Ų11657.6 Ų57.654%0.54227%0.266SS..Hα-helixtrans-61.3-35.1178-74.1-179.8100113.2G702 Q704 K710G702-Q706 WeakPolarHBondContact O-CB 3.42Å; G702-Q706 WeakPolarHBondContact O-CG 3.44Å; G702-Q706 PolarHBondContact O-N 2.85Å; Q704-Q706 PolarHBondContact O-N 3.47Å; Q706-K710 WeakPolarHBondContact O-CG 3.04Å; Q706-K710 PolarHBondContact O-N 3.37Å; Q706-K710 VanDerWaalsContact O-N 3.11Å
707M94.1Very high92Very high74 Ų7456.4 Ų56.437%0.36528%0.276SS..Hα-helixtrans-62.5-49.7175.3-171.7-172.279.400111.1R703 Q704 I705 K710 I711R703-M707 WeakPolarHBondContact O-CB 3.45Å; R703-M707 PolarHBondContact O-N 3.39Å; Q704-M707 WeakPolarHBondContact O-CB 3.41Å; Q704-M707 PolarHBondContact O-N 3.31Å; I705-M707 VanDerWaalsContact C-N 3.3Å; I705-M707 PolarHBondContact O-N 2.86Å; M707-K710 PolarHBondContact O-N 3.4Å; M707-I711 HydrophobicContact CG-CD1 4.45Å; M707-I711 WeakPolarHBondContact O-CG1 3.49Å; M707-I711 PolarHBondContact O-N 3.23Å
708Y93.2Very high91.5Very high0 Ų063 Ų630%030%0.304CS..Hα-helixtrans-70-35.7179.2-62.3-58.2000112.6Q704 I705 K710 I711 V712 V737 L774 Y775 C778 V782Q704-Y708 HydrophobicContact CB-CE2 4.29Å; Q704-Y708 WeakPolarHBondContact O-CD2 3.16Å; Q704-Y708 PolarHBondContact O-N 2.91Å; I705-Y708 PolarHBondContact O-N 3.41Å; Y708-K710 PolarHBondContact O-N 3.35Å; Y708-I711 HydrophobicContact CD1-CD1 4.41Å; Y708-I711 PolarHBondContact O-N 3Å; Y708-V712 WeakPolarHBondContact O-CG2 3.15Å; Y708-V712 PolarHBondContact O-N 2.91Å; Y708-V737 VanDerWaalsContact CB-CG2 3.42Å; Y708-V737 HydrophobicContact CD2-CG2 4.4Å; Y708-V737 HydrophobicContact CG-CG2 4.23Å; Y708-L774 HydrophobicContact CD2-CD2 4.22Å; Y708-L774 HydrophobicContact CD2-CG 4.11Å; Y708-L774 HydrophobicContact CE2-CD2 4.4Å; Y708-L774 HydrophobicContact CE2-CG 4.09Å; Y708-Y775 VanDerWaalsContact OH-CD2 3.31Å; Y708-Y775 WeakPolarHBondContact OH-CD2 3.27Å; Y708-C778 HydrophobicContact CD1-CB 3.76Å; Y708-C778 HydrophobicContact CD2-CB 3.96Å; Y708-C778 HydrophobicContact CE1-CB 3.74Å; Y708-C778 HydrophobicContact CE2-CB 3.94Å; Y708-C778 HydrophobicContact CG-CB 3.9Å; Y708-V782 HydrophobicContact CD1-CG1 4.31Å; Y708-V782 HydrophobicContact CD1-CG2 3.91Å; Y708-V782 HydrophobicContact CE1-CG2 3.72Å
709M91.6Very high91Very high49 Ų4965.7 Ų65.724%0.24132%0.318CS..Hα-helixtrans-55.9-49.5172.1-74-173.77700111.6I705 I711 V712 E713 V737 M741I705-M709 HydrophobicContact CG2-CG 4.42Å; I705-M709 HydrophobicContact CG2-SD 4.22Å; I705-M709 WeakPolarHBondContact O-CG 3.45Å; I705-M709 PolarHBondContact O-N 2.93Å; M709-I711 VanDerWaalsContact C-N 3.26Å; M709-I711 PolarHBondContact O-N 3.5Å; M709-V712 CarbonylContact O-C 3.32Å; M709-V712 PolarHBondContact O-N 3.46Å; M709-V712 VanDerWaalsContact O-N 3.11Å; M709-E713 WeakPolarHBondContact O-CG 3.39Å; M709-E713 PolarHBondContact O-N 3.5Å; M709-V737 HydrophobicContact CG-CG1 3.42Å; M709-V737 VanDerWaalsContact CG-CG1 3.42Å; M709-M741 HydrophobicContact CE-CE 4.3Å; M709-M741 HydrophobicContact SD-CE 3.34Å; M709-M741 WeakPolarHBondContact SD-CE 3.37Å
710K92Very high90.2Very high132 Ų13266.2 Ų66.257%0.57432%0.321SS*.Hα-helixtrans-61.5-33179.4-75.4177.3178.2-179.30113.1Q706 M707 Y708 S714Q706-K710 WeakPolarHBondContact O-CG 3.04Å; Q706-K710 PolarHBondContact O-N 3.37Å; Q706-K710 VanDerWaalsContact O-N 3.11Å; M707-K710 PolarHBondContact O-N 3.4Å; Y708-K710 PolarHBondContact O-N 3.35Å; K710-S714 WeakPolarHBondContact O-CB 3.36Å; K710-S714 PolarHBondContact O-N 3.42Å; K710-S714 PolarHBondContact O-OG 2.88Å
711I89.2Confident89.5Confident19 Ų1968.8 Ų68.810%0.09733%0.333CS..Hα-helixtrans-70.2-42.6175.2-64.2165000110.6M707 Y708 M709 E713 S714 Y715 Y722 V782M707-I711 HydrophobicContact CG-CD1 4.45Å; M707-I711 WeakPolarHBondContact O-CG1 3.49Å; M707-I711 PolarHBondContact O-N 3.23Å; Y708-I711 HydrophobicContact CD1-CD1 4.41Å; Y708-I711 PolarHBondContact O-N 3Å; M709-I711 VanDerWaalsContact C-N 3.26Å; M709-I711 PolarHBondContact O-N 3.5Å; I711-E713 VanDerWaalsContact C-N 3.33Å; I711-E713 PolarHBondContact O-N 3.09Å; I711-S714 PolarHBondContact O-N 3.27Å; I711-Y715 WeakPolarHBondContact O-CB 3.33Å; I711-Y715 PolarHBondContact O-N 3.46Å; I711-Y722 HydrophobicContact CB-CE1 4.43Å; I711-Y722 HydrophobicContact CG1-CE1 4.17Å; I711-Y722 HydrophobicContact CG2-CD1 3.56Å; I711-Y722 HydrophobicContact CG2-CD2 4.48Å; I711-Y722 HydrophobicContact CG2-CE1 3.52Å; I711-Y722 HydrophobicContact CG2-CE2 4.46Å; I711-Y722 HydrophobicContact CG2-CG 4.05Å; I711-V782 HydrophobicContact CB-CG1 4.42Å; I711-V782 HydrophobicContact CD1-CB 4.1Å; I711-V782 HydrophobicContact CD1-CG1 4.42Å; I711-V782 HydrophobicContact CD1-CG2 4Å; I711-V782 HydrophobicContact CG2-CB 3.94Å; I711-V782 HydrophobicContact CG2-CG1 3.75Å
712V88.7Confident88.9Confident3 Ų370.5 Ų70.52%0.01834%0.339CS..Hα-helixtrans-64-37.4174.1171.50000111.6Y708 M709 K716 V730 V733 D734Y708-V712 WeakPolarHBondContact O-CG2 3.15Å; Y708-V712 PolarHBondContact O-N 2.91Å; M709-V712 CarbonylContact O-C 3.32Å; M709-V712 PolarHBondContact O-N 3.46Å; M709-V712 VanDerWaalsContact O-N 3.11Å; V712-K716 HydrophobicContact CG1-CD 4.02Å; V712-K716 VanDerWaalsContact CG1-CE 3.47Å; V712-K716 WeakPolarHBondContact O-CB 3.41Å; V712-K716 WeakPolarHBondContact O-CD 3.45Å; V712-K716 VanDerWaalsContact O-CG 3.26Å; V712-K716 WeakPolarHBondContact O-CG 3.41Å; V712-K716 PolarHBondContact O-N 3.27Å; V712-V730 HydrophobicContact CG2-CG1 4.19Å; V712-V733 HydrophobicContact CG2-CB 4.47Å; V712-V733 HydrophobicContact CG2-CG1 3.82Å; V712-D734 HydrophobicContact CG1-CB 3.88Å; V712-D734 HydrophobicContact CG2-CB 4.32Å
713E88.7Confident88.3Confident110 Ų11073.3 Ų73.351%0.51435%0.351SS..Hα-helixtrans-66.7-44173.6-73171.617400111.8M709 I711 Y715 K716 A717M709-E713 WeakPolarHBondContact O-CG 3.39Å; M709-E713 PolarHBondContact O-N 3.5Å; I711-E713 VanDerWaalsContact C-N 3.33Å; I711-E713 PolarHBondContact O-N 3.09Å; E713-Y715 VanDerWaalsContact C-N 3.34Å; E713-Y715 PolarHBondContact O-N 3.43Å; E713-K716 PolarHBondContact O-N 2.83Å; E713-A717 WeakPolarHBondContact O-CB 3.37Å; E713-A717 PolarHBondContact O-N 3.49Å
714S88.9Confident87.6Confident32 Ų3269.5 Ų69.522%0.22434%0.339CS..Hα-helixtrans-62-41.2175.1-58.40000111.6K710 I711 A717 K718 D719K710-S714 WeakPolarHBondContact O-CB 3.36Å; K710-S714 PolarHBondContact O-N 3.42Å; K710-S714 PolarHBondContact O-OG 2.88Å; I711-S714 PolarHBondContact O-N 3.27Å; S714-A717 CarbonylContact O-C 3.59Å; S714-A717 PolarHBondContact O-N 3.34Å; S714-K718 PolarHBondContact O-N 3.18Å; S714-K718 VanDerWaalsContact O-N 3.17Å; S714-D719 WeakPolarHBondContact O-CB 3.46Å; S714-D719 PolarHBondContact O-N 2.87Å
715Y88.2Confident87.2Confident40 Ų4068.9 Ų68.916%0.15734%0.336CS..Hα-helixtrans-58.3-50.9171.6-178.7-98.8000112.1I711 E713 A717 K718 Y722 L725 E727 V730I711-Y715 WeakPolarHBondContact O-CB 3.33Å; I711-Y715 PolarHBondContact O-N 3.46Å; E713-Y715 VanDerWaalsContact C-N 3.34Å; E713-Y715 PolarHBondContact O-N 3.43Å; Y715-A717 PolarHBondContact O-N 2.82Å; Y715-K718 PolarHBondContact O-N 2.87Å; Y715-Y722 WeakPolarHBondContact CD2-O 3.31Å; Y715-L725 HydrophobicContact CD2-CB 4.1Å; Y715-L725 HydrophobicContact CE2-CB 3.84Å; Y715-L725 VanDerWaalsContact CE2-O 3.23Å; Y715-L725 WeakPolarHBondContact CE2-O 3.46Å; Y715-L725 PolarHBondContact OH-O 3.42Å; Y715-E727 WeakPolarHBondContact OH-CA 3.42Å; Y715-E727 PolarHBondContact OH-N 3.45Å; Y715-V730 HydrophobicContact CD1-CB 4.14Å; Y715-V730 HydrophobicContact CD1-CG1 3.57Å; Y715-V730 HydrophobicContact CD1-CG2 4.36Å; Y715-V730 HydrophobicContact CD2-CG2 4.09Å; Y715-V730 HydrophobicContact CE1-CB 4.06Å; Y715-V730 HydrophobicContact CE1-CG1 3.99Å; Y715-V730 HydrophobicContact CE1-CG2 4.31Å; Y715-V730 HydrophobicContact CE2-CG2 4.06Å; Y715-V730 HydrophobicContact CG-CB 4.45Å; Y715-V730 HydrophobicContact CG-CG1 3.85Å; Y715-V730 HydrophobicContact CG-CG2 4.24Å
716K86.6Confident86.9Confident130 Ų13072.6 Ų72.657%0.56536%0.357SS*.Hα-helixtrans-62.6-26.5177.6-71.6166.3-178.5172.50112.7V712 E713 K718 D734V712-K716 HydrophobicContact CG1-CD 4.02Å; V712-K716 VanDerWaalsContact CG1-CE 3.47Å; V712-K716 WeakPolarHBondContact O-CB 3.41Å; V712-K716 WeakPolarHBondContact O-CD 3.45Å; V712-K716 VanDerWaalsContact O-CG 3.26Å; V712-K716 WeakPolarHBondContact O-CG 3.41Å; V712-K716 PolarHBondContact O-N 3.27Å; E713-K716 PolarHBondContact O-N 2.83Å; K716-K718 VanDerWaalsContact C-N 3.33Å; K716-D734 IonicContact NZ-OD1 3.25Å; K716-D734 IonicContact NZ-OD2 3.57Å; K716-D734 PolarHBondContact NZ-OD2 3.46Å
717A88.3Confident86.4Confident78 Ų7873.8 Ų73.865%0.64536%0.362SS*.THydrogen-bonded Turntrans-83.4-2.7173.500000114.3E713 S714 Y715 D719E713-A717 WeakPolarHBondContact O-CB 3.37Å; E713-A717 PolarHBondContact O-N 3.49Å; S714-A717 CarbonylContact O-C 3.59Å; S714-A717 PolarHBondContact O-N 3.34Å; Y715-A717 PolarHBondContact O-N 2.82Å; A717-D719 VanDerWaalsContact C-N 3.31Å
718K84.5Confident86Confident144 Ų14476.8 Ų76.863%0.62638%0.379SS*.THydrogen-bonded Turntrans57.839.7-172.7-56.8-173.1152.8-730113.5S714 Y715 K716 E720 D723S714-K718 PolarHBondContact O-N 3.18Å; S714-K718 VanDerWaalsContact O-N 3.17Å; Y715-K718 PolarHBondContact O-N 2.87Å; K716-K718 VanDerWaalsContact C-N 3.33Å; K718-E720 PolarHBondContact O-N 3.15Å; K718-D723 WeakPolarHBondContact CG-OD1 3.47Å; K718-D723 IonicContact NZ-OD1 2.75Å; K718-D723 PolarHBondContact NZ-OD1 2.73Å; K718-D723 IonicContact NZ-OD2 2.65Å
719D83.1Confident85.7Confident67 Ų6779.7 Ų79.736%0.35839%0.393SS..  trans-55.8126.9166.6-172.4-42.6000109.1S714 A717 Q721 Y722 D723S714-D719 WeakPolarHBondContact O-CB 3.46Å; S714-D719 PolarHBondContact O-N 2.87Å; A717-D719 VanDerWaalsContact C-N 3.31Å; D719-Q721 PolarHBondContact O-N 2.92Å; D719-Q721 WeakPolarHBondContact OD1-CB 3.44Å; D719-Q721 PolarHBondContact OD1-N 3.47Å; D719-Y722 HydrophobicContact CB-CD2 4.36Å; D719-Y722 PolarHBondContact O-N 3.31Å; D719-D723 PolarHBondContact O-N 2.75Å
720E77.6Confident85.4Confident157 Ų15777.7 Ų77.773%0.73438%0.383SS*.THydrogen-bonded Turntrans-51.7-32.3179.7-78-164.9-163.800112.3K718 Y722 K786K718-E720 PolarHBondContact O-N 3.15Å; E720-Y722 PolarHBondContact O-N 3.21Å; E720-K786 WeakPolarHBondContact O-CE 3.5Å; E720-K786 PolarHBondContact O-NZ 3.45Å
721Q78.8Confident85.3Confident118 Ų11875.2 Ų75.255%0.55138%0.379SS*.THydrogen-bonded Turntrans-65.3-22-178.3-176.2170.2-13.600113.1D719 H724D719-Q721 PolarHBondContact O-N 2.92Å; D719-Q721 WeakPolarHBondContact OD1-CB 3.44Å; D719-Q721 PolarHBondContact OD1-N 3.47Å; Q721-H724 PolarHBondContact O-CE1 3.03Å
722Y82.7Confident85.2Confident36 Ų3682.3 Ų82.314%0.14140%0.404CS..THydrogen-bonded Turntrans-131-18.5-170-56.5-75.5000116I711 Y715 D719 E720 H724 L725I711-Y722 HydrophobicContact CB-CE1 4.43Å; I711-Y722 HydrophobicContact CG1-CE1 4.17Å; I711-Y722 HydrophobicContact CG2-CD1 3.56Å; I711-Y722 HydrophobicContact CG2-CD2 4.48Å; I711-Y722 HydrophobicContact CG2-CE1 3.52Å; I711-Y722 HydrophobicContact CG2-CE2 4.46Å; I711-Y722 HydrophobicContact CG2-CG 4.05Å; Y715-Y722 WeakPolarHBondContact CD2-O 3.31Å; D719-Y722 HydrophobicContact CB-CD2 4.36Å; D719-Y722 PolarHBondContact O-N 3.31Å; E720-Y722 PolarHBondContact O-N 3.21Å; Y722-H724 PolarHBondContact O-N 3.26Å; Y722-L725 HydrophobicContact CD1-CD1 4.13Å; Y722-L725 WeakPolarHBondContact O-CB 3.45Å; Y722-L725 WeakPolarHBondContact O-CG 3.36Å; Y722-L725 PolarHBondContact O-N 3.43Å
723D81.4Confident85.3Confident73 Ų7382.3 Ų82.339%0.3940%0.404SS..THydrogen-bonded Turntrans-55.1-12.8-177.2-172.270.7000114.7K718 D719K718-D723 WeakPolarHBondContact CG-OD1 3.47Å; K718-D723 IonicContact NZ-OD1 2.75Å; K718-D723 PolarHBondContact NZ-OD1 2.73Å; K718-D723 IonicContact NZ-OD2 2.65Å; D719-D723 PolarHBondContact O-N 2.75Å
724H81.6Confident85.4Confident56 Ų5679 Ų7926%0.25939%0.39SS..THydrogen-bonded Turntrans-83.4-4.2173.671.7-83.5000115.6Q721 Y722 K784 K786Q721-H724 PolarHBondContact O-CE1 3.03Å; Y722-H724 PolarHBondContact O-N 3.26Å; H724-K784 PolarHBondContact NE2-O 3.14Å; H724-K786 HydrophobicContact CB-CG 4.33Å; H724-K786 WeakPolarHBondContact ND1-CG 3.44Å
725L84.9Confident85.5Confident10 Ų1082.6 Ų82.65%0.05240%0.403CS..SBendtrans-77.1149.1179.4-63.7178.6000111.9Y715 Y722 V730 V781 K784Y715-L725 HydrophobicContact CD2-CB 4.1Å; Y715-L725 HydrophobicContact CE2-CB 3.84Å; Y715-L725 VanDerWaalsContact CE2-O 3.23Å; Y715-L725 WeakPolarHBondContact CE2-O 3.46Å; Y715-L725 PolarHBondContact OH-O 3.42Å; Y722-L725 HydrophobicContact CD1-CD1 4.13Å; Y722-L725 WeakPolarHBondContact O-CB 3.45Å; Y722-L725 WeakPolarHBondContact O-CG 3.36Å; Y722-L725 PolarHBondContact O-N 3.43Å; L725-V730 HydrophobicContact CB-CG2 3.51Å; L725-V730 HydrophobicContact CD1-CG2 4.01Å; L725-V730 HydrophobicContact CG-CG2 4.42Å; L725-V781 WeakPolarHBondContact CD2-O 3.27Å; L725-K784 HydrophobicContact CD2-CB 3.85Å
726D86.7Confident85.6Confident81 Ų8182.6 Ų82.643%0.43341%0.405SS..  trans-68.3131.5-179.9177.7-85.2000111.8L728 E729 V730D726-L728 VanDerWaalsContact C-N 3.32Å; D726-L728 PolarHBondContact O-N 3.39Å; D726-L728 WeakPolarHBondContact OD1-CA 3.36Å; D726-L728 WeakPolarHBondContact OD1-CB 3.19Å; D726-L728 PolarHBondContact OD1-N 2.92Å; D726-E729 HydrophobicContact CB-CB 4.12Å; D726-E729 HydrophobicContact CB-CG 4.09Å; D726-E729 PolarHBondContact O-N 3.41Å; D726-E729 PolarHBondContact OD1-N 3.06Å; D726-V730 WeakPolarHBondContact O-CG2 3.31Å; D726-V730 PolarHBondContact O-N 3.4Å
727E84.6Confident85.9Confident140 Ų14076.4 Ų76.465%0.65438%0.378SS*.Hα-helixtrans-63.6-34.9-173.7-171.9177.2-173.200112.7Y715 T731Y715-E727 WeakPolarHBondContact OH-CA 3.42Å; Y715-E727 PolarHBondContact OH-N 3.45Å; E727-T731 WeakPolarHBondContact O-CB 3.33Å; E727-T731 PolarHBondContact O-N 3.22Å; E727-T731 PolarHBondContact O-OG1 2.99Å
728L84.8Confident86.1Confident138 Ų13876.4 Ų76.472%0.72337%0.367SS*.Hα-helixtrans-75.2-38.9178.6-58.6174.6000111D726 R732D726-L728 VanDerWaalsContact C-N 3.32Å; D726-L728 PolarHBondContact O-N 3.39Å; D726-L728 WeakPolarHBondContact OD1-CA 3.36Å; D726-L728 WeakPolarHBondContact OD1-CB 3.19Å; D726-L728 PolarHBondContact OD1-N 2.92Å; L728-R732 WeakPolarHBondContact O-CB 3.22Å; L728-R732 PolarHBondContact O-N 3.34Å
729E86.6Confident86.5Confident61 Ų6173.8 Ų73.829%0.28536%0.357SS..Hα-helixtrans-67.4-41.9173.8-66.8-172.4133.200112.4D726 R732 V733 V781 K784D726-E729 HydrophobicContact CB-CB 4.12Å; D726-E729 HydrophobicContact CB-CG 4.09Å; D726-E729 PolarHBondContact O-N 3.41Å; D726-E729 PolarHBondContact OD1-N 3.06Å; E729-R732 WeakPolarHBondContact O-CB 3.35Å; E729-R732 PolarHBondContact O-N 2.99Å; E729-V733 WeakPolarHBondContact O-CG2 3.08Å; E729-V733 PolarHBondContact O-N 2.97Å; E729-V781 HydrophobicContact CB-CG1 3.7Å; E729-V781 HydrophobicContact CB-CG2 4.2Å; E729-K784 IonicContact OE1-NZ 2.67Å; E729-K784 PolarHBondContact OE1-NZ 3.28Å; E729-K784 IonicContact OE2-NZ 3.96Å; E729-K784 PolarHBondContact OE2-NZ 3.42Å
730V86.6Confident87Confident6 Ų670.7 Ų70.74%0.03634%0.341CS..Hα-helixtrans-68.5-37.6175.8178.90000111.1V712 Y715 L725 D726 R732 V733 D734V712-V730 HydrophobicContact CG2-CG1 4.19Å; Y715-V730 HydrophobicContact CD1-CB 4.14Å; Y715-V730 HydrophobicContact CD1-CG1 3.57Å; Y715-V730 HydrophobicContact CD1-CG2 4.36Å; Y715-V730 HydrophobicContact CD2-CG2 4.09Å; Y715-V730 HydrophobicContact CE1-CB 4.06Å; Y715-V730 HydrophobicContact CE1-CG1 3.99Å; Y715-V730 HydrophobicContact CE1-CG2 4.31Å; Y715-V730 HydrophobicContact CE2-CG2 4.06Å; Y715-V730 HydrophobicContact CG-CB 4.45Å; Y715-V730 HydrophobicContact CG-CG1 3.85Å; Y715-V730 HydrophobicContact CG-CG2 4.24Å; L725-V730 HydrophobicContact CB-CG2 3.51Å; L725-V730 HydrophobicContact CD1-CG2 4.01Å; L725-V730 HydrophobicContact CG-CG2 4.42Å; D726-V730 WeakPolarHBondContact O-CG2 3.31Å; D726-V730 PolarHBondContact O-N 3.4Å; V730-R732 VanDerWaalsContact C-N 3.28Å; V730-R732 PolarHBondContact O-N 3.31Å; V730-V733 WeakPolarHBondContact O-CB 3.37Å; V730-V733 PolarHBondContact O-N 2.99Å; V730-D734 PolarHBondContact O-N 2.95Å
731T88.6Confident87.7Confident80 Ų8066 Ų6649%0.49132%0.319SS..Hα-helixtrans-60.8-38.4171.2-61.80000111.4E727 D734 Q735E727-T731 WeakPolarHBondContact O-CB 3.33Å; E727-T731 PolarHBondContact O-N 3.22Å; E727-T731 PolarHBondContact O-OG1 2.99Å; T731-D734 PolarHBondContact O-N 2.72Å; T731-Q735 PolarHBondContact O-N 2.91Å
732R88.6Confident88.4Confident168 Ų16862.9 Ų62.963%0.63431%0.314SS*.Hα-helixtrans-67.2-38.5173.3-177.7-180176.4-176.2-1.5112.5L728 E729 V730 Q735 Q736L728-R732 WeakPolarHBondContact O-CB 3.22Å; L728-R732 PolarHBondContact O-N 3.34Å; E729-R732 WeakPolarHBondContact O-CB 3.35Å; E729-R732 PolarHBondContact O-N 2.99Å; V730-R732 VanDerWaalsContact C-N 3.28Å; V730-R732 PolarHBondContact O-N 3.31Å; R732-Q735 PolarHBondContact O-N 3.21Å; R732-Q736 WeakPolarHBondContact O-CG 3.39Å; R732-Q736 PolarHBondContact O-N 3.34Å
733V89.2Confident89Confident3 Ų364.4 Ų64.42%0.01832%0.32CS..Hα-helixtrans-61.5-48.5172.6169.60000110.2V712 E729 V730 Q735 Q736 V737 C778 V781 V782V712-V733 HydrophobicContact CG2-CB 4.47Å; V712-V733 HydrophobicContact CG2-CG1 3.82Å; E729-V733 WeakPolarHBondContact O-CG2 3.08Å; E729-V733 PolarHBondContact O-N 2.97Å; V730-V733 WeakPolarHBondContact O-CB 3.37Å; V730-V733 PolarHBondContact O-N 2.99Å; V733-Q735 VanDerWaalsContact C-N 3.33Å; V733-Q735 PolarHBondContact O-N 3.31Å; V733-Q736 PolarHBondContact O-N 2.79Å; V733-V737 HydrophobicContact CG1-CG2 4.1Å; V733-V737 WeakPolarHBondContact O-CB 3.49Å; V733-V737 WeakPolarHBondContact O-CG2 3.34Å; V733-V737 PolarHBondContact O-N 3.03Å; V733-C778 HydrophobicContact CG1-CB 4.12Å; V733-C778 HydrophobicContact CG2-CB 4.35Å; V733-V781 HydrophobicContact CG2-CB 3.73Å; V733-V781 HydrophobicContact CG2-CG1 3.78Å; V733-V781 HydrophobicContact CG2-CG2 4.06Å; V733-V782 HydrophobicContact CG1-CG1 4.19Å; V733-V782 HydrophobicContact CG2-CG1 4.49Å
734D90.4Very high89.6Confident41 Ų4162.1 Ų62.122%0.21931%0.307CS..Hα-helixtrans-55.6-47.6176.1-165.122.9000110.9V712 K716 V730 T731 Q736 V737 N738V712-D734 HydrophobicContact CG1-CB 3.88Å; V712-D734 HydrophobicContact CG2-CB 4.32Å; K716-D734 IonicContact NZ-OD1 3.25Å; K716-D734 IonicContact NZ-OD2 3.57Å; K716-D734 PolarHBondContact NZ-OD2 3.46Å; V730-D734 PolarHBondContact O-N 2.95Å; T731-D734 PolarHBondContact O-N 2.72Å; D734-Q736 PolarHBondContact O-N 2.71Å; D734-V737 PolarHBondContact O-N 3.12Å; D734-N738 WeakPolarHBondContact O-CB 3.38Å; D734-N738 PolarHBondContact O-N 2.93Å; D734-N738 PolarHBondContact O-ND2 3Å; D734-N738 PolarHBondContact OD1-ND2 3.36Å
735Q91.3Very high90.1Very high107 Ų10762.7 Ų62.750%0.531%0.312SS..Hα-helixtrans-57.8-50.7174.8-177.1-178.7-13.300112.3T731 R732 V733 V737 N738 E739T731-Q735 PolarHBondContact O-N 2.91Å; R732-Q735 PolarHBondContact O-N 3.21Å; V733-Q735 VanDerWaalsContact C-N 3.33Å; V733-Q735 PolarHBondContact O-N 3.31Å; Q735-V737 VanDerWaalsContact C-N 3.32Å; Q735-V737 PolarHBondContact O-N 3.11Å; Q735-N738 PolarHBondContact O-N 3.17Å; Q735-E739 HydrophobicContact CG-CG 4.43Å; Q735-E739 VanDerWaalsContact CG-OE1 3.32Å; Q735-E739 WeakPolarHBondContact CG-OE1 3.26Å; Q735-E739 PolarHBondContact NE2-OE1 3.12Å; Q735-E739 WeakPolarHBondContact O-CB 3.16Å; Q735-E739 WeakPolarHBondContact O-CG 3.32Å; Q735-E739 PolarHBondContact O-N 3.04Å
736Q90.6Very high90.5Very high40 Ų4065.6 Ų65.619%0.18733%0.331CS..Hα-helixtrans-64.2-35-178.8-70.9-62.3-83.800113R732 V733 D734 E739 A740R732-Q736 WeakPolarHBondContact O-CG 3.39Å; R732-Q736 PolarHBondContact O-N 3.34Å; V733-Q736 PolarHBondContact O-N 2.79Å; D734-Q736 PolarHBondContact O-N 2.71Å; Q736-E739 PolarHBondContact NE2-OE2 3.17Å; Q736-A740 VanDerWaalsContact O-CB 3.31Å; Q736-A740 WeakPolarHBondContact O-CB 3.34Å; Q736-A740 PolarHBondContact O-N 2.91Å
737V92.8Very high90.8Very high1 Ų163.8 Ų63.81%0.00632%0.319CS..Hα-helixtrans-69.5-42.8176.4172.30000111I705 Y708 M709 V733 D734 Q735 A740 M741 L774I705-V737 HydrophobicContact CG2-CG1 4.04Å; Y708-V737 VanDerWaalsContact CB-CG2 3.42Å; Y708-V737 HydrophobicContact CD2-CG2 4.4Å; Y708-V737 HydrophobicContact CG-CG2 4.23Å; M709-V737 HydrophobicContact CG-CG1 3.42Å; M709-V737 VanDerWaalsContact CG-CG1 3.42Å; V733-V737 HydrophobicContact CG1-CG2 4.1Å; V733-V737 WeakPolarHBondContact O-CB 3.49Å; V733-V737 WeakPolarHBondContact O-CG2 3.34Å; V733-V737 PolarHBondContact O-N 3.03Å; D734-V737 PolarHBondContact O-N 3.12Å; Q735-V737 VanDerWaalsContact C-N 3.32Å; Q735-V737 PolarHBondContact O-N 3.11Å; V737-A740 PolarHBondContact O-N 3.33Å; V737-M741 WeakPolarHBondContact O-CB 3.3Å; V737-M741 PolarHBondContact O-N 3.43Å; V737-L774 HydrophobicContact CG2-CD1 4.11Å
738N92.7Very high91.1Very high77 Ų7760 Ų6041%0.41230%0.302SS..Hα-helixtrans-67.5-39.2174.8-75.9-71.7000112.2D734 Q735 M741 A742D734-N738 WeakPolarHBondContact O-CB 3.38Å; D734-N738 PolarHBondContact O-N 2.93Å; D734-N738 PolarHBondContact O-ND2 3Å; D734-N738 PolarHBondContact OD1-ND2 3.36Å; Q735-N738 PolarHBondContact O-N 3.17Å; N738-M741 PolarHBondContact O-N 3.11Å; N738-A742 VanDerWaalsContact O-CB 3.31Å; N738-A742 WeakPolarHBondContact O-CB 3.4Å; N738-A742 PolarHBondContact O-N 3.43Å
739E93.2Very high91.3Very high90 Ų9058.3 Ų58.342%0.42129%0.294SS..Hα-helixtrans-61.8-43.7172.5-77.1175.4-16600111.9Q735 Q736 A742 W743Q735-E739 HydrophobicContact CG-CG 4.43Å; Q735-E739 VanDerWaalsContact CG-OE1 3.32Å; Q735-E739 WeakPolarHBondContact CG-OE1 3.26Å; Q735-E739 PolarHBondContact NE2-OE1 3.12Å; Q735-E739 WeakPolarHBondContact O-CB 3.16Å; Q735-E739 WeakPolarHBondContact O-CG 3.32Å; Q735-E739 PolarHBondContact O-N 3.04Å; Q736-E739 PolarHBondContact NE2-OE2 3.17Å; E739-A742 PolarHBondContact O-N 2.97Å; E739-W743 WeakPolarHBondContact O-CB 3.18Å; E739-W743 PolarHBondContact O-N 2.8Å
740A92.6Very high91.5Very high1 Ų159.3 Ų59.31%0.00830%0.298CS..Hα-helixtrans-65.9-39.4176.100000112.4I705 Q736 V737 W743 M744 L774I705-A740 HydrophobicContact CD1-CB 4.05Å; I705-A740 HydrophobicContact CG1-CB 4.18Å; Q736-A740 VanDerWaalsContact O-CB 3.31Å; Q736-A740 WeakPolarHBondContact O-CB 3.34Å; Q736-A740 PolarHBondContact O-N 2.91Å; V737-A740 PolarHBondContact O-N 3.33Å; A740-W743 PolarHBondContact O-N 2.78Å; A740-M744 VanDerWaalsContact O-CB 3.27Å; A740-M744 WeakPolarHBondContact O-CB 3.47Å; A740-M744 PolarHBondContact O-N 2.71Å; A740-L774 HydrophobicContact CB-CD1 3.94Å; A740-L774 HydrophobicContact CB-CD2 4.03Å; A740-L774 HydrophobicContact CB-CG 4.44Å
741M93.7Very high91.7Very high58 Ų5859.8 Ų59.829%0.28630%0.3SS..Hα-helixtrans-64.8-45.4173.3-179.1176.6-72.700111.9I705 M709 V737 N738 W743 M744 N745I705-M741 HydrophobicContact CD1-CB 4.48Å; I705-M741 HydrophobicContact CG2-CB 4.09Å; I705-M741 HydrophobicContact CG2-CE 3.62Å; M709-M741 HydrophobicContact CE-CE 4.3Å; M709-M741 HydrophobicContact SD-CE 3.34Å; M709-M741 WeakPolarHBondContact SD-CE 3.37Å; V737-M741 WeakPolarHBondContact O-CB 3.3Å; V737-M741 PolarHBondContact O-N 3.43Å; N738-M741 PolarHBondContact O-N 3.11Å; M741-W743 VanDerWaalsContact C-N 3.33Å; M741-W743 PolarHBondContact O-N 2.68Å; M741-M744 PolarHBondContact O-N 3.27Å; M741-N745 WeakPolarHBondContact CG-ND2 3.32Å; M741-N745 WeakPolarHBondContact O-CB 3.45Å; M741-N745 PolarHBondContact O-N 2.72Å; M741-N745 PolarHBondContact O-ND2 3.06Å
742A93.6Very high91.6Very high54 Ų5461.8 Ų61.845%0.44631%0.308SS..Hα-helixtrans-61.5-42.1177.500000111.4N738 E739 T746N738-A742 VanDerWaalsContact O-CB 3.31Å; N738-A742 WeakPolarHBondContact O-CB 3.4Å; N738-A742 PolarHBondContact O-N 3.43Å; E739-A742 PolarHBondContact O-N 2.97Å; A742-T746 VanDerWaalsContact O-CB 3.22Å; A742-T746 WeakPolarHBondContact O-CB 3.37Å; A742-T746 PolarHBondContact O-N 3.17Å; A742-T746 PolarHBondContact O-OG1 3.23Å
743W95.4Very high91.5Very high67 Ų6758.6 Ų58.625%0.25431%0.311SS..Hα-helixtrans-62.3-48.6173.5-178.293.2000112F698 L701 E739 A740 M741 T746 K747 V762 I767 K770F698-W743 HydrophobicContact CE1-CZ3 4.35Å; L701-W743 HydrophobicContact CD2-CE3 4.13Å; L701-W743 HydrophobicContact CD2-CZ3 3.81Å; E739-W743 WeakPolarHBondContact O-CB 3.18Å; E739-W743 PolarHBondContact O-N 2.8Å; A740-W743 PolarHBondContact O-N 2.78Å; M741-W743 VanDerWaalsContact C-N 3.33Å; M741-W743 PolarHBondContact O-N 2.68Å; W743-T746 PolarHBondContact O-N 2.67Å; W743-K747 HydrophobicContact CD2-CG 4.11Å; W743-K747 HydrophobicContact CH2-CG 4.4Å; W743-K747 HydrophobicContact CZ2-CG 3.95Å; W743-K747 WeakPolarHBondContact O-CB 3.21Å; W743-K747 PolarHBondContact O-N 2.75Å; W743-V762 HydrophobicContact CH2-CG2 3.84Å; W743-V762 HydrophobicContact CZ2-CG2 4.01Å; W743-I767 HydrophobicContact CH2-CG1 4.1Å; W743-I767 HydrophobicContact CZ3-CG1 4.4Å; W743-K770 HydrophobicContact CD2-CD 4.25Å; W743-K770 HydrophobicContact CD2-CG 4.13Å; W743-K770 HydrophobicContact CE3-CB 4.32Å; W743-K770 HydrophobicContact CE3-CD 4.45Å; W743-K770 HydrophobicContact CE3-CG 3.83Å; W743-K770 HydrophobicContact CH2-CB 4.01Å; W743-K770 HydrophobicContact CH2-CG 4.35Å; W743-K770 HydrophobicContact CZ2-CB 4.5Å; W743-K770 HydrophobicContact CZ3-CB 3.91Å; W743-K770 HydrophobicContact CZ3-CG 3.96Å
744M93.3Very high91.4Very high25 Ų2561.8 Ų61.812%0.12333%0.326CS..Hα-helixtrans-58.8-51.9179.5174.6173.9170.900111.2F698 L701 I705 A740 M741 T746 K747 M748F698-M744 HydrophobicContact CB-CE 4.14Å; F698-M744 HydrophobicContact CD1-CE 4.32Å; F698-M744 HydrophobicContact CD1-CG 3.86Å; F698-M744 HydrophobicContact CE1-CG 4.08Å; F698-M744 WeakPolarHBondContact O-CE 3.49Å; L701-M744 HydrophobicContact CB-SD 4.36Å; L701-M744 HydrophobicContact CD2-CB 4.08Å; L701-M744 HydrophobicContact CD2-CG 4.26Å; L701-M744 HydrophobicContact CD2-SD 4.16Å; L701-M744 HydrophobicContact CG-SD 4.01Å; I705-M744 HydrophobicContact CD1-CB 4.39Å; I705-M744 HydrophobicContact CD1-SD 3.9Å; A740-M744 VanDerWaalsContact O-CB 3.27Å; A740-M744 WeakPolarHBondContact O-CB 3.47Å; A740-M744 PolarHBondContact O-N 2.71Å; M741-M744 PolarHBondContact O-N 3.27Å; M744-T746 VanDerWaalsContact C-N 3.34Å; M744-T746 PolarHBondContact O-N 2.94Å; M744-K747 PolarHBondContact O-N 2.88Å; M744-M748 WeakPolarHBondContact O-CB 3.42Å; M744-M748 PolarHBondContact O-N 3.02Å
745N92.5Very high91.2Very high68 Ų6864.4 Ų64.436%0.36434%0.34SS..Hα-helixtrans-62.3-41.1178.6-71.5-23.8000111.7M741 N749M741-N745 WeakPolarHBondContact CG-ND2 3.32Å; M741-N745 WeakPolarHBondContact O-CB 3.45Å; M741-N745 PolarHBondContact O-N 2.72Å; M741-N745 PolarHBondContact O-ND2 3.06Å; N745-N749 VanDerWaalsContact O-CB 3.26Å; N745-N749 WeakPolarHBondContact O-CB 3.46Å; N745-N749 PolarHBondContact O-N 2.7Å; N745-N749 PolarHBondContact O-ND2 3.12Å
746T93.8Very high91Very high72 Ų7263 Ų6344%0.44234%0.335SS..Hα-helixtrans-62.2-50.2176.7-61.30000111.5A742 W743 M744 N749 Q750A742-T746 VanDerWaalsContact O-CB 3.22Å; A742-T746 WeakPolarHBondContact O-CB 3.37Å; A742-T746 PolarHBondContact O-N 3.17Å; A742-T746 PolarHBondContact O-OG1 3.23Å; W743-T746 PolarHBondContact O-N 2.67Å; M744-T746 VanDerWaalsContact C-N 3.34Å; M744-T746 PolarHBondContact O-N 2.94Å; T746-N749 PolarHBondContact O-N 2.91Å; T746-Q750 WeakPolarHBondContact O-CB 3.26Å; T746-Q750 VanDerWaalsContact O-CG 3.25Å; T746-Q750 WeakPolarHBondContact O-CG 3.47Å; T746-Q750 PolarHBondContact O-N 2.69Å
747K92.6Very high90.7Very high43 Ų4362.5 Ų62.519%0.18734%0.335CS..Hα-helixtrans-68.4-39.1-179.2-77.3-58.8-155.91680112.7F698 W743 M744 Q751 V761 V762F698-K747 HydrophobicContact CZ-CB 4.14Å; W743-K747 HydrophobicContact CD2-CG 4.11Å; W743-K747 HydrophobicContact CH2-CG 4.4Å; W743-K747 HydrophobicContact CZ2-CG 3.95Å; W743-K747 WeakPolarHBondContact O-CB 3.21Å; W743-K747 PolarHBondContact O-N 2.75Å; M744-K747 PolarHBondContact O-N 2.88Å; K747-Q751 VanDerWaalsContact O-CB 3.23Å; K747-Q751 WeakPolarHBondContact O-CB 3.37Å; K747-Q751 PolarHBondContact O-N 3.24Å; K747-V761 PolarHBondContact NZ-O 3Å; K747-V762 HydrophobicContact CB-CB 4.39Å; K747-V762 HydrophobicContact CB-CG1 4.06Å; K747-V762 HydrophobicContact CD-CB 4.08Å; K747-V762 HydrophobicContact CG-CB 4.36Å
748M90.4Very high90.4Very high60 Ų6065.7 Ų65.730%0.29635%0.354SS..Hα-helixtrans-64.9-44.2175.9-171.3172.868.300111.2F698 M744 Q751 N752F698-M748 HydrophobicContact CD2-CG 4.46Å; F698-M748 HydrophobicContact CE2-CB 4.06Å; F698-M748 HydrophobicContact CE2-CG 4.28Å; F698-M748 HydrophobicContact CZ-CB 4.03Å; M744-M748 WeakPolarHBondContact O-CB 3.42Å; M744-M748 PolarHBondContact O-N 3.02Å; M748-Q751 PolarHBondContact O-N 2.89Å; M748-N752 WeakPolarHBondContact O-CB 3.26Å; M748-N752 PolarHBondContact O-N 2.82Å; M748-N752 PolarHBondContact O-ND2 2.76Å; M748-N752 PolarHBondContact O-OD1 3.11Å
749N89.9Confident90.1Very high103 Ų10366.8 Ų66.855%0.55136%0.36SS*.Hα-helixtrans-63.7-45.3176-73.4-22.4000112.4N745 T746 Q751 N752 S753N745-N749 VanDerWaalsContact O-CB 3.26Å; N745-N749 WeakPolarHBondContact O-CB 3.46Å; N745-N749 PolarHBondContact O-N 2.7Å; N745-N749 PolarHBondContact O-ND2 3.12Å; T746-N749 PolarHBondContact O-N 2.91Å; N749-Q751 VanDerWaalsContact C-N 3.33Å; N749-Q751 PolarHBondContact O-N 2.88Å; N749-N752 PolarHBondContact O-N 3.42Å; N749-S753 PolarHBondContact O-N 2.88Å; N749-S753 VanDerWaalsContact O-N 3.14Å; N749-S753 PolarHBondContact O-OG 3.3Å
750Q90.3Very high89.8Confident82 Ų8263.6 Ų63.638%0.38335%0.347SS..Hα-helixtrans-60-43.2175.2-72171.7-5.400111.7T746 S753 Q754 V761T746-Q750 WeakPolarHBondContact O-CB 3.26Å; T746-Q750 VanDerWaalsContact O-CG 3.25Å; T746-Q750 WeakPolarHBondContact O-CG 3.47Å; T746-Q750 PolarHBondContact O-N 2.69Å; Q750-S753 PolarHBondContact O-N 2.97Å; Q750-S753 PolarHBondContact O-OG 3.44Å; Q750-Q754 PolarHBondContact O-N 3.37Å; Q750-V761 HydrophobicContact CB-CB 4.39Å; Q750-V761 HydrophobicContact CB-CG1 3.84Å
751Q89.8Confident89.6Confident15 Ų1565.5 Ų65.57%0.0736%0.359CS..Hα-helixtrans-67.6-34.5177.8-177.558.572.300113K747 M748 N749 S753 Q754 P760K747-Q751 VanDerWaalsContact O-CB 3.23Å; K747-Q751 WeakPolarHBondContact O-CB 3.37Å; K747-Q751 PolarHBondContact O-N 3.24Å; M748-Q751 PolarHBondContact O-N 2.89Å; N749-Q751 VanDerWaalsContact C-N 3.33Å; N749-Q751 PolarHBondContact O-N 2.88Å; Q751-S753 VanDerWaalsContact C-N 3.27Å; Q751-S753 PolarHBondContact O-N 2.96Å; Q751-Q754 WeakPolarHBondContact O-CB 3.36Å; Q751-Q754 PolarHBondContact O-N 3.2Å; Q751-P760 VanDerWaalsContact OE1-CA 3.26Å
752N87.8Confident89.5Confident123 Ų12362.7 Ų62.766%0.65835%0.345SS*.Hα-helixtrans-70.9-23.1176.1-69.9-11.7000112.5M748 N749M748-N752 WeakPolarHBondContact O-CB 3.26Å; M748-N752 PolarHBondContact O-N 2.82Å; M748-N752 PolarHBondContact O-ND2 2.76Å; M748-N752 PolarHBondContact O-OD1 3.11Å; N749-N752 PolarHBondContact O-N 3.42Å
753S86Confident89.5Confident100 Ų10065.1 Ų65.170%0.69935%0.345SS*.THydrogen-bonded Turntrans-84.8-7.2170.661.20000114.6N749 Q750 Q751N749-S753 PolarHBondContact O-N 2.88Å; N749-S753 VanDerWaalsContact O-N 3.14Å; N749-S753 PolarHBondContact O-OG 3.3Å; Q750-S753 PolarHBondContact O-N 2.97Å; Q750-S753 PolarHBondContact O-OG 3.44Å; Q751-S753 VanDerWaalsContact C-N 3.27Å; Q751-S753 PolarHBondContact O-N 2.96Å
754Q87.3Confident89.4Confident70 Ų7062.7 Ų62.733%0.32734%0.338SS..SBendtrans-90.3137.4-176.7-173.675.8-27.100110.9Q750 Q751 V758 D759 V761Q750-Q754 PolarHBondContact O-N 3.37Å; Q751-Q754 WeakPolarHBondContact O-CB 3.36Å; Q751-Q754 PolarHBondContact O-N 3.2Å; Q754-V758 HydrophobicContact CG-CG2 3.82Å; Q754-D759 PolarHBondContact NE2-O 3.33Å; Q754-V761 HydrophobicContact CB-CG2 3.87Å; Q754-V761 HydrophobicContact CG-CG2 3.87Å
755N85.4Confident89.4Confident97 Ų9763.9 Ų63.952%0.51936%0.357SS..  trans-71.1141.6175.2-172.4-62.6000110.9T757 V758N755-T757 PolarHBondContact O-N 2.84Å; N755-T757 WeakPolarHBondContact OD1-CB 3.35Å; N755-T757 WeakPolarHBondContact OD1-CG2 3.4Å; N755-T757 PolarHBondContact OD1-N 2.98Å; N755-T757 PolarHBondContact OD1-OG1 2.87Å; N755-V758 HydrophobicContact CB-CG2 4.24Å; N755-V758 WeakPolarHBondContact O-CG2 3.36Å; N755-V758 PolarHBondContact O-N 2.82Å
756L86.7Confident89.4Confident76 Ų7664.8 Ų64.840%0.39836%0.359SS..THydrogen-bonded Turntrans-65.6-18.3-177.8-62.8179.9000114.3K637 F638K637-L756 HydrophobicContact CB-CD1 4.22Å; K637-L756 VanDerWaalsContact O-CB 3.27Å; K637-L756 WeakPolarHBondContact O-CB 3.22Å; F638-L756 HydrophobicContact CD1-CB 3.95Å; F638-L756 HydrophobicContact CE1-CB 3.99Å; F638-L756 HydrophobicContact CE1-CD1 4.08Å; F638-L756 HydrophobicContact CE1-CD2 4.12Å; F638-L756 HydrophobicContact CE1-CG 4.28Å; F638-L756 HydrophobicContact CZ-CD1 4.28Å
757T85.1Confident89.4Confident31 Ų3161.3 Ų61.319%0.1934%0.338CS..THydrogen-bonded Turntrans-80.3-13.8179.463.40000114.2V639 N640 K687 N755V639-T757 WeakPolarHBondContact O-CG2 3.48Å; N640-T757 HydrophobicContact CB-CG2 4.46Å; K687-T757 PolarHBondContact NZ-O 3.48Å; N755-T757 PolarHBondContact O-N 2.84Å; N755-T757 WeakPolarHBondContact OD1-CB 3.35Å; N755-T757 WeakPolarHBondContact OD1-CG2 3.4Å; N755-T757 PolarHBondContact OD1-N 2.98Å; N755-T757 PolarHBondContact OD1-OG1 2.87Å
758V86.7Confident89.5Confident67 Ų6763.9 Ų63.941%0.40635%0.349SS..SBendtrans-107.9164.9178-66.70000111.4Q754 N755Q754-V758 HydrophobicContact CG-CG2 3.82Å; N755-V758 HydrophobicContact CB-CG2 4.24Å; N755-V758 WeakPolarHBondContact O-CG2 3.36Å; N755-V758 PolarHBondContact O-N 2.82Å
759D85.6Confident89.7Confident100 Ų10063.7 Ų63.754%0.53536%0.357SS..  trans-62.4144.1-176.6-74.119.1000111.9K687 Q754K687-D759 WeakPolarHBondContact CE-OD1 3.39Å; K687-D759 IonicContact NZ-OD1 2.71Å; Q754-D759 PolarHBondContact NE2-O 3.33Å
760P87.6Confident89.9Confident24 Ų2460.8 Ų60.816%0.15634%0.339CS..  trans-71.6148.7-17529.4-36.1000112.8E690 Q751 V762 K763E690-P760 HydrophobicContact CG-CG 4.5Å; Q751-P760 VanDerWaalsContact OE1-CA 3.26Å; P760-V762 PolarHBondContact O-N 3.39Å; P760-K763 HydrophobicContact CG-CG 4.14Å
761V89.1Confident90Very high40 Ų4057.5 Ų57.524%0.24233%0.325CS..SBendtrans-75.5-16.5-179.2-169.80000112K747 Q750 Q754K747-V761 PolarHBondContact NZ-O 3Å; Q750-V761 HydrophobicContact CB-CB 4.39Å; Q750-V761 HydrophobicContact CB-CG1 3.84Å; Q754-V761 HydrophobicContact CB-CG2 3.87Å; Q754-V761 HydrophobicContact CG-CG2 3.87Å
762V91.1Very high90.2Very high0 Ų064.3 Ų64.30%035%0.354CS..SBendtrans-151.4133.216964.80000109.7R694 F698 W743 K747 P760 E766 I767R694-V762 PolarHBondContact NE-O 3.4Å; F698-V762 HydrophobicContact CE2-CG1 4.24Å; F698-V762 HydrophobicContact CZ-CG1 3.76Å; W743-V762 HydrophobicContact CH2-CG2 3.84Å; W743-V762 HydrophobicContact CZ2-CG2 4.01Å; K747-V762 HydrophobicContact CB-CB 4.39Å; K747-V762 HydrophobicContact CB-CG1 4.06Å; K747-V762 HydrophobicContact CD-CB 4.08Å; K747-V762 HydrophobicContact CG-CB 4.36Å; P760-V762 PolarHBondContact O-N 3.39Å; V762-E766 HydrophobicContact CG2-CB 3.69Å; V762-E766 HydrophobicContact CG2-CG 4.44Å; V762-I767 HydrophobicContact CG1-CD1 4.12Å; V762-I767 HydrophobicContact CG1-CG1 4.31Å; V762-I767 HydrophobicContact CG2-CG1 3.87Å
763K93.3Very high90.5Very high105 Ų10562.9 Ų62.946%0.45734%0.344SS..  trans-85.4153.4177.6-66.3-168.7179.6-168.80112.1E690 P760 G765 E766 I767E690-K763 WeakPolarHBondContact OE1-CA 3.34Å; E690-K763 WeakPolarHBondContact OE1-CB 3.43Å; E690-K763 VanDerWaalsContact OE2-CA 3.28Å; E690-K763 WeakPolarHBondContact OE2-CA 3.34Å; P760-K763 HydrophobicContact CG-CG 4.14Å; K763-G765 PolarHBondContact O-N 3.46Å; K763-G765 VanDerWaalsContact O-N 3.15Å; K763-E766 HydrophobicContact CB-CG 4.47Å; K763-E766 PolarHBondContact N-OE1 3.28Å; K763-E766 WeakPolarHBondContact O-CB 3.38Å; K763-E766 PolarHBondContact O-N 3.33Å; K763-I767 PolarHBondContact O-N 2.74Å
764V92.8Very high90.9Very high15 Ų1558.4 Ų58.49%0.09131%0.312CS..Hα-helixtrans-53.6-35.5175169.20000111.5E690 E693 R694 A697 K768E690-V764 VanDerWaalsContact CD-N 3.34Å; E690-V764 WeakPolarHBondContact OE1-CB 3.47Å; E690-V764 PolarHBondContact OE1-N 2.91Å; E690-V764 PolarHBondContact OE2-N 3.18Å; E693-V764 HydrophobicContact CB-CG1 4.23Å; E693-V764 HydrophobicContact CB-CG2 3.7Å; R694-V764 HydrophobicContact CB-CG2 4.03Å; A697-V764 HydrophobicContact CB-CG1 4.31Å; V764-K768 HydrophobicContact CG1-CD 3.76Å; V764-K768 VanDerWaalsContact CG1-CE 3.48Å; V764-K768 HydrophobicContact CG1-CG 4.45Å; V764-K768 VanDerWaalsContact CG1-NZ 3.35Å; V764-K768 WeakPolarHBondContact O-CB 3.26Å; V764-K768 WeakPolarHBondContact O-CG 3.44Å; V764-K768 PolarHBondContact O-N 3.29Å
765G93Very high91.1Very high51 Ų5160.6 Ų60.653%0.52632%0.318SS..Hα-helixtrans-64-37.7174.600000114.3K763 A769K763-G765 PolarHBondContact O-N 3.46Å; K763-G765 VanDerWaalsContact O-N 3.15Å; G765-A769 WeakPolarHBondContact O-CB 3.2Å; G765-A769 PolarHBondContact O-N 3.2Å
766E93.2Very high91.4Very high86 Ų8659.2 Ų59.240%0.40232%0.32SS..Hα-helixtrans-69.8-41.7177.5-66.3170.5-102.300111.3V762 K763 A769 K770V762-E766 HydrophobicContact CG2-CB 3.69Å; V762-E766 HydrophobicContact CG2-CG 4.44Å; K763-E766 HydrophobicContact CB-CG 4.47Å; K763-E766 PolarHBondContact N-OE1 3.28Å; K763-E766 WeakPolarHBondContact O-CB 3.38Å; K763-E766 PolarHBondContact O-N 3.33Å; E766-A769 WeakPolarHBondContact O-CB 3.42Å; E766-A769 PolarHBondContact O-N 2.7Å; E766-K770 PolarHBondContact O-N 3.38Å
767I93.8Very high91.6Very high0 Ų057.2 Ų57.20%031%0.312CS..Hα-helixtrans-63.8-48.8176.2-57.3168000109.8R694 A697 F698 L701 W743 V762 K763 A769 K770 T771R694-I767 HydrophobicContact CG-CD1 3.51Å; A697-I767 HydrophobicContact CB-CB 4.12Å; A697-I767 HydrophobicContact CB-CD1 4.28Å; A697-I767 HydrophobicContact CB-CG2 3.91Å; A697-I767 WeakPolarHBondContact O-CG2 3.22Å; F698-I767 HydrophobicContact CD1-CD1 3.82Å; F698-I767 HydrophobicContact CD1-CG1 4.25Å; F698-I767 HydrophobicContact CD1-CG2 4.06Å; F698-I767 HydrophobicContact CD2-CD1 3.87Å; F698-I767 HydrophobicContact CE1-CD1 3.71Å; F698-I767 HydrophobicContact CE1-CG1 3.96Å; F698-I767 HydrophobicContact CE1-CG2 4.48Å; F698-I767 HydrophobicContact CE2-CD1 3.76Å; F698-I767 HydrophobicContact CG-CD1 3.9Å; F698-I767 HydrophobicContact CZ-CD1 3.69Å; F698-I767 HydrophobicContact CZ-CG1 4.25Å; L701-I767 HydrophobicContact CB-CG2 4.18Å; L701-I767 HydrophobicContact CD2-CG2 4.01Å; W743-I767 HydrophobicContact CH2-CG1 4.1Å; W743-I767 HydrophobicContact CZ3-CG1 4.4Å; V762-I767 HydrophobicContact CG1-CD1 4.12Å; V762-I767 HydrophobicContact CG1-CG1 4.31Å; V762-I767 HydrophobicContact CG2-CG1 3.87Å; K763-I767 PolarHBondContact O-N 2.74Å; I767-A769 PolarHBondContact O-N 2.93Å; I767-K770 PolarHBondContact O-N 2.93Å; I767-T771 PolarHBondContact O-N 3.07Å; I767-T771 PolarHBondContact O-OG1 2.85Å; I767-T771 VanDerWaalsContact O-OG1 3.07Å
768K94.4Very high91.8Very high97 Ų9755.8 Ų55.842%0.42230%0.303SS..Hα-helixtrans-62.4-24.9176.7-71.4174.1-178.7169.20112.4E693 A697 V764 K772E693-K768 IonicContact OE2-NZ 3.27Å; A697-K768 HydrophobicContact CB-CG 4.39Å; V764-K768 HydrophobicContact CG1-CD 3.76Å; V764-K768 VanDerWaalsContact CG1-CE 3.48Å; V764-K768 HydrophobicContact CG1-CG 4.45Å; V764-K768 VanDerWaalsContact CG1-NZ 3.35Å; V764-K768 WeakPolarHBondContact O-CB 3.26Å; V764-K768 WeakPolarHBondContact O-CG 3.44Å; V764-K768 PolarHBondContact O-N 3.29Å; K768-K772 WeakPolarHBondContact O-CG 3.47Å; K768-K772 PolarHBondContact O-N 3.24Å
769A95.2Very high92Very high56 Ų5654 Ų5446%0.46329%0.292SS..Hα-helixtrans-74.1-46.1168.800000112.1G765 E766 I767 T771 K772 E773G765-A769 WeakPolarHBondContact O-CB 3.2Å; G765-A769 PolarHBondContact O-N 3.2Å; E766-A769 WeakPolarHBondContact O-CB 3.42Å; E766-A769 PolarHBondContact O-N 2.7Å; I767-A769 PolarHBondContact O-N 2.93Å; A769-T771 VanDerWaalsContact C-N 3.33Å; A769-T771 PolarHBondContact O-N 3.29Å; A769-K772 WeakPolarHBondContact O-CB 3.25Å; A769-K772 PolarHBondContact O-N 3.25Å; A769-K772 VanDerWaalsContact O-N 3.1Å; A769-E773 PolarHBondContact O-N 3.06Å
770K93.3Very high92.2Very high42 Ų4252.9 Ų52.918%0.18329%0.29CS..Hα-helixtrans-62-37.2177.8-162.176.1-153.2167.20112.5W743 E766 I767 E773 L774W743-K770 HydrophobicContact CD2-CD 4.25Å; W743-K770 HydrophobicContact CD2-CG 4.13Å; W743-K770 HydrophobicContact CE3-CB 4.32Å; W743-K770 HydrophobicContact CE3-CD 4.45Å; W743-K770 HydrophobicContact CE3-CG 3.83Å; W743-K770 HydrophobicContact CH2-CB 4.01Å; W743-K770 HydrophobicContact CH2-CG 4.35Å; W743-K770 HydrophobicContact CZ2-CB 4.5Å; W743-K770 HydrophobicContact CZ3-CB 3.91Å; W743-K770 HydrophobicContact CZ3-CG 3.96Å; E766-K770 PolarHBondContact O-N 3.38Å; I767-K770 PolarHBondContact O-N 2.93Å; K770-E773 WeakPolarHBondContact CD-OE2 3.23Å; K770-E773 WeakPolarHBondContact CE-OE2 3.05Å; K770-E773 IonicContact NZ-OE1 2.59Å; K770-E773 PolarHBondContact NZ-OE1 3.33Å; K770-E773 IonicContact NZ-OE2 3.51Å; K770-E773 PolarHBondContact NZ-OE2 3.02Å; K770-E773 WeakPolarHBondContact O-CB 3.38Å; K770-E773 PolarHBondContact O-N 3.22Å; K770-L774 WeakPolarHBondContact O-CB 3.4Å; K770-L774 PolarHBondContact O-N 3.22Å
771T93.4Very high92.1Very high13 Ų1352.5 Ų52.58%0.0829%0.287CS..Hα-helixtrans-61.7-42.6172.6-47.40000111.7E700 Q704 I767 A769 Y775E700-T771 HydrophobicContact CG-CG2 4.35Å; Q704-T771 HydrophobicContact CG-CG2 4.26Å; I767-T771 PolarHBondContact O-N 3.07Å; I767-T771 PolarHBondContact O-OG1 2.85Å; I767-T771 VanDerWaalsContact O-OG1 3.07Å; A769-T771 VanDerWaalsContact C-N 3.33Å; A769-T771 PolarHBondContact O-N 3.29Å; T771-Y775 WeakPolarHBondContact O-CB 3.13Å; T771-Y775 PolarHBondContact O-N 2.88Å
772K94.3Very high92Very high158 Ų15851.2 Ų51.269%0.68728%0.279SS*.Hα-helixtrans-67-37.3176.4-73.4175.7179.1-176.50112.5K768 A769 A776K768-K772 WeakPolarHBondContact O-CG 3.47Å; K768-K772 PolarHBondContact O-N 3.24Å; A769-K772 WeakPolarHBondContact O-CB 3.25Å; A769-K772 PolarHBondContact O-N 3.25Å; A769-K772 VanDerWaalsContact O-N 3.1Å; K772-A776 VanDerWaalsContact O-CB 3.29Å; K772-A776 WeakPolarHBondContact O-CB 3.4Å; K772-A776 PolarHBondContact O-N 3.18Å
773E93.9Very high91.8Very high93 Ų9355.3 Ų55.344%0.43530%0.304SS..Hα-helixtrans-61.7-51.2175.1-167.9-167.4146.200110.9A769 K770 Y775 A776 S777A769-E773 PolarHBondContact O-N 3.06Å; K770-E773 WeakPolarHBondContact CD-OE2 3.23Å; K770-E773 WeakPolarHBondContact CE-OE2 3.05Å; K770-E773 IonicContact NZ-OE1 2.59Å; K770-E773 PolarHBondContact NZ-OE1 3.33Å; K770-E773 IonicContact NZ-OE2 3.51Å; K770-E773 PolarHBondContact NZ-OE2 3.02Å; K770-E773 WeakPolarHBondContact O-CB 3.38Å; K770-E773 PolarHBondContact O-N 3.22Å; E773-Y775 VanDerWaalsContact C-N 3.35Å; E773-Y775 PolarHBondContact O-N 3.39Å; E773-A776 PolarHBondContact O-N 3.22Å; E773-S777 PolarHBondContact O-N 2.99Å; E773-S777 PolarHBondContact O-OG 3.47Å
774L93.3Very high91.4Very high5 Ų554.3 Ų54.33%0.02630%0.3CS..Hα-helixtrans-60.8-41.6176.9-178.667.1000112.2L701 I705 Y708 V737 A740 K770 S777 C778L701-L774 HydrophobicContact CD1-CD2 4.17Å; I705-L774 HydrophobicContact CD1-CD2 4.49Å; I705-L774 HydrophobicContact CG1-CD2 3.48Å; I705-L774 VanDerWaalsContact CG1-CD2 3.48Å; Y708-L774 HydrophobicContact CD2-CD2 4.22Å; Y708-L774 HydrophobicContact CD2-CG 4.11Å; Y708-L774 HydrophobicContact CE2-CD2 4.4Å; Y708-L774 HydrophobicContact CE2-CG 4.09Å; V737-L774 HydrophobicContact CG2-CD1 4.11Å; A740-L774 HydrophobicContact CB-CD1 3.94Å; A740-L774 HydrophobicContact CB-CD2 4.03Å; A740-L774 HydrophobicContact CB-CG 4.44Å; K770-L774 WeakPolarHBondContact O-CB 3.4Å; K770-L774 PolarHBondContact O-N 3.22Å; L774-S777 PolarHBondContact O-N 3.42Å; L774-S777 PolarHBondContact O-OG 2.86Å; L774-S777 VanDerWaalsContact O-OG 3.09Å; L774-C778 VanDerWaalsContact O-CB 3.3Å; L774-C778 WeakPolarHBondContact O-CB 3.34Å; L774-C778 PolarHBondContact O-N 3.32Å
775Y92.8Very high90.7Very high116 Ų11659.2 Ų59.246%0.45533%0.332SS..Hα-helixtrans-61.3-46.6174.4-176.7-91.5000111.6Y708 T771 E773 S777 N779Y708-Y775 VanDerWaalsContact OH-CD2 3.31Å; Y708-Y775 WeakPolarHBondContact OH-CD2 3.27Å; T771-Y775 WeakPolarHBondContact O-CB 3.13Å; T771-Y775 PolarHBondContact O-N 2.88Å; E773-Y775 VanDerWaalsContact C-N 3.35Å; E773-Y775 PolarHBondContact O-N 3.39Å; Y775-S777 PolarHBondContact O-N 2.94Å; Y775-N779 HydrophobicContact CD1-CB 4.37Å; Y775-N779 HydrophobicContact CD2-CB 4.09Å; Y775-N779 HydrophobicContact CE1-CB 4.18Å; Y775-N779 HydrophobicContact CE2-CB 3.86Å; Y775-N779 WeakPolarHBondContact CE2-OD1 3.45Å; Y775-N779 HydrophobicContact CG-CB 4.32Å; Y775-N779 WeakPolarHBondContact O-CB 3.37Å; Y775-N779 PolarHBondContact O-N 2.97Å; Y775-N779 PolarHBondContact OH-ND2 3.16Å
776A92.1Very high89.9Confident68 Ų6862 Ų6256%0.56233%0.33SS*.Hα-helixtrans-67.3-32.2-179.600000113.3K772 E773 P780K772-A776 VanDerWaalsContact O-CB 3.29Å; K772-A776 WeakPolarHBondContact O-CB 3.4Å; K772-A776 PolarHBondContact O-N 3.18Å; E773-A776 PolarHBondContact O-N 3.22Å; A776-P780 WeakPolarHBondContact O-CD 3.46Å; A776-P780 WeakPolarHBondContact O-CG 3.42Å
777S88.9Confident88.5Confident35 Ų3562.6 Ų62.625%0.24534%0.341CS..Hα-helixtrans-79.3-39.5176.861.30000113.3E773 L774 Y775E773-S777 PolarHBondContact O-N 2.99Å; E773-S777 PolarHBondContact O-OG 3.47Å; L774-S777 PolarHBondContact O-N 3.42Å; L774-S777 PolarHBondContact O-OG 2.86Å; L774-S777 VanDerWaalsContact O-OG 3.09Å; Y775-S777 PolarHBondContact O-N 2.94Å
778C90.6Very high86.7Confident0 Ų072.5 Ų72.50%038%0.384CS..Hα-helixtrans-97.5-40.1-169.6-62.30000113.9Y708 V733 L774 V781 V782Y708-C778 HydrophobicContact CD1-CB 3.76Å; Y708-C778 HydrophobicContact CD2-CB 3.96Å; Y708-C778 HydrophobicContact CE1-CB 3.74Å; Y708-C778 HydrophobicContact CE2-CB 3.94Å; Y708-C778 HydrophobicContact CG-CB 3.9Å; V733-C778 HydrophobicContact CG1-CB 4.12Å; V733-C778 HydrophobicContact CG2-CB 4.35Å; L774-C778 VanDerWaalsContact O-CB 3.3Å; L774-C778 WeakPolarHBondContact O-CB 3.34Å; L774-C778 PolarHBondContact O-N 3.32Å; C778-V781 PolarHBondContact O-N 3.35Å; C778-V781 VanDerWaalsContact O-N 3.14Å; C778-V782 PolarHBondContact O-N 3.2Å
779N90.8Very high84.4Confident31 Ų3174.6 Ų74.617%0.16641%0.405CS..Hα-helixtrans-58.5-42.4-174.9-162.683.4000113.7Y775 V781 V782 T783Y775-N779 HydrophobicContact CD1-CB 4.37Å; Y775-N779 HydrophobicContact CD2-CB 4.09Å; Y775-N779 HydrophobicContact CE1-CB 4.18Å; Y775-N779 HydrophobicContact CE2-CB 3.86Å; Y775-N779 WeakPolarHBondContact CE2-OD1 3.45Å; Y775-N779 HydrophobicContact CG-CB 4.32Å; Y775-N779 WeakPolarHBondContact O-CB 3.37Å; Y775-N779 PolarHBondContact O-N 2.97Å; Y775-N779 PolarHBondContact OH-ND2 3.16Å; N779-V781 PolarHBondContact O-N 3.14Å; N779-V782 PolarHBondContact O-N 2.8Å; N779-T783 WeakPolarHBondContact O-CB 3.27Å; N779-T783 WeakPolarHBondContact O-CG2 3.3Å; N779-T783 PolarHBondContact O-N 3.38Å; N779-T783 PolarHBondContact O-OG1 2.83Å
780P90.1Very high81.9Confident75 Ų7580.5 Ų80.549%0.48742%0.423SS..Hα-helixtrans-67.6-15179.9-21.134.7000115A776 K784A776-P780 WeakPolarHBondContact O-CD 3.46Å; A776-P780 WeakPolarHBondContact O-CG 3.42Å; P780-K784 WeakPolarHBondContact O-CG 3.28Å
781V85.7Confident79.5Confident16 Ų1684.3 Ų84.310%0.09745%0.452CS..Hα-helixtrans-87.4-56.5173.4176.50000109.7L725 E729 V733 C778 N779 T783 K784L725-V781 WeakPolarHBondContact CD2-O 3.27Å; E729-V781 HydrophobicContact CB-CG1 3.7Å; E729-V781 HydrophobicContact CB-CG2 4.2Å; V733-V781 HydrophobicContact CG2-CB 3.73Å; V733-V781 HydrophobicContact CG2-CG1 3.78Å; V733-V781 HydrophobicContact CG2-CG2 4.06Å; C778-V781 PolarHBondContact O-N 3.35Å; C778-V781 VanDerWaalsContact O-N 3.14Å; N779-V781 PolarHBondContact O-N 3.14Å; V781-T783 PolarHBondContact O-N 2.83Å; V781-T783 VanDerWaalsContact O-N 3.14Å; V781-K784 WeakPolarHBondContact O-CG 3.46Å; V781-K784 PolarHBondContact O-N 3.4Å
782V85.6Confident77.4Confident13 Ų1389.7 Ų89.78%0.07949%0.487CS..Hα-helixtrans-70.3-12.8-172-59.20000114.7Y708 I711 V733 C778 N779Y708-V782 HydrophobicContact CD1-CG1 4.31Å; Y708-V782 HydrophobicContact CD1-CG2 3.91Å; Y708-V782 HydrophobicContact CE1-CG2 3.72Å; I711-V782 HydrophobicContact CB-CG1 4.42Å; I711-V782 HydrophobicContact CD1-CB 4.1Å; I711-V782 HydrophobicContact CD1-CG1 4.42Å; I711-V782 HydrophobicContact CD1-CG2 4Å; I711-V782 HydrophobicContact CG2-CB 3.94Å; I711-V782 HydrophobicContact CG2-CG1 3.75Å; V733-V782 HydrophobicContact CG1-CG1 4.19Å; V733-V782 HydrophobicContact CG2-CG1 4.49Å; C778-V782 PolarHBondContact O-N 3.2Å; N779-V782 PolarHBondContact O-N 2.8Å
783T87.5Confident74.7Confident87 Ų8792.1 Ų92.153%0.53450%0.498SS..THydrogen-bonded Turntrans-98.95.4177.1580000114.2N779 V781N779-T783 WeakPolarHBondContact O-CB 3.27Å; N779-T783 WeakPolarHBondContact O-CG2 3.3Å; N779-T783 PolarHBondContact O-N 3.38Å; N779-T783 PolarHBondContact O-OG1 2.83Å; V781-T783 PolarHBondContact O-N 2.83Å; V781-T783 VanDerWaalsContact O-N 3.14Å
784K84.3Confident71.9Confident84 Ų8495.9 Ų95.937%0.36552%0.515SS..PPolyproline II helixtrans-63.8131.3177.1-70.5-177.2-179.6-173.10111.1H724 L725 E729 P780 V781H724-K784 PolarHBondContact NE2-O 3.14Å; L725-K784 HydrophobicContact CD2-CB 3.85Å; E729-K784 IonicContact OE1-NZ 2.67Å; E729-K784 PolarHBondContact OE1-NZ 3.28Å; E729-K784 IonicContact OE2-NZ 3.96Å; E729-K784 PolarHBondContact OE2-NZ 3.42Å; P780-K784 WeakPolarHBondContact O-CG 3.28Å; V781-K784 WeakPolarHBondContact O-CG 3.46Å; V781-K784 PolarHBondContact O-N 3.4Å
785P79.1Confident69.2Low117 Ų117104.2 Ų104.276%0.7655%0.554SS**PPolyproline II helixtrans-74.7156179.931.4-35.8000112.4
786K75.8Confident66.4Low110 Ų110106.8 Ų106.848%0.47857%0.568SS.*PPolyproline II helixtrans-57.7138.8173.4-73.6-177.3176.5-168.80112.2E720 H724E720-K786 WeakPolarHBondContact O-CE 3.5Å; E720-K786 PolarHBondContact O-NZ 3.45Å; H724-K786 HydrophobicContact CB-CG 4.33Å; H724-K786 WeakPolarHBondContact ND1-CG 3.44Å
787P64.9Low63.3Low99 Ų99109.3 Ų109.364%0.64358%0.576SS**PPolyproline II helixtrans-57.2143.2163.7-22.433.7000111.5
788K54.3Low60.6Low208 Ų208115 Ų11590%0.90460%0.599SS**PPolyproline II helixtrans-85.7141.5170.3-68.7-177.5178.4-179.90109.8
789V48Very low57.7Low141 Ų141121.8 Ų121.886%0.85564%0.635SS**  trans-105.9134177.6-176.90000109.4
790E41.1Very low54.9Low180 Ų180123.7 Ų123.784%0.84166%0.662SS**  trans-114.7146.6174-65.5-168.2160.400111.3
791P42.5Very low52.5Low122 Ų122125.8 Ų125.879%0.79268%0.676SS**  trans-86.5155.2-174.734.2-35.6000114.1
792P50.1Low49.9Very low126 Ų126130.9 Ų130.982%0.81871%0.706SS**  trans-88169.3-167.535.8-38.4000115.5
793K38.2Very low47.4Very low209 Ų209137.7 Ų137.791%0.90974%0.743SS**  trans-139.7162.2166.7-101-175.5176.3-179.30112.6
794E35.1Very low45Very low172 Ų172137.3 Ų137.380%0.80476%0.756SS**  trans-97.4161.3-158-57.9171.286.300116.2K796E794-K796 IonicContact OE1-NZ 3.6Å
795E36.9Very low43.2Very low180 Ų180142.6 Ų142.684%0.84178%0.782SS**  trans-86.6156.7165.3-56.1179.7121.200113.5
796K33.3Very low41.5Very low170 Ų170141 Ų14174%0.73978%0.779SS**  trans169.2137.7149.9-90.6140.5-159.3153.70107.7E794E794-K796 IonicContact OE1-NZ 3.6Å
797T27.4Very low39.6Very low121 Ų121144 Ų14474%0.74280%0.795SS**  cis-159.9-176.7-3.46.10000107.1
798E31Very low39.5Very low154 Ų154144.6 Ų144.672%0.7280%0.798SS**  cis-158.3179.215.7-140-177.784.200113
799N30.5Very low38.5Very low142 Ų142143.1 Ų143.176%0.75980%0.795SS**  trans-4.2139.8155.4-61.1-29.7000120.3
800G30.9Very low37.8Very low71 Ų71141.6 Ų141.673%0.73279%0.79SS**  cis148.6171.40.500000111.5
801P41.3Very low37.3Very low120 Ų120141.8 Ų141.878%0.77979%0.791SS**  cis-134.5173.32.342.1-25000116.7
802V30.7Very low37.7Very low122 Ų122141.7 Ų141.774%0.73979%0.791SS**SBendtrans7992.5163.8-1620000119.6
803N32.9Very low36.7Very low157 Ų157139.7 Ų139.784%0.8479%0.792SS**  trans77.751140.2-57.48.8000122.9
804G37.2Very low36.2Very low79 Ų79136.9 Ų136.981%0.81479%0.787SS**  52.7138129.100000124.4
805Q45.6Very low36.7Very low194 Ų194134.3 Ų134.391%0.90779%0.786SS**  trans-152.3157177-72.4-174.5-39.200114.6
806A44.9Very low36.5Very low85 Ų85131.9 Ų131.970%0.70278%0.779SS**  trans75.8173.9142.100000123.4
807E35.6Very low36.2Very low173 Ų173133.3 Ų133.381%0.80879%0.785SS**  trans-142.4-162.9-173.8-47.1101.1102.100110.3
808P62.2Low36.4Very low110 Ų110132.6 Ų132.671%0.71478%0.78SS**  cis-143.1-162.5-5.745.7-24.5000116.8
809E32.9Very low36.1Very low178 Ų178134.1 Ų134.183%0.83279%0.785SS**  trans52.6120.3151.1-73-174.7145.200125.9
810S33.6Very low36.7Very low109 Ų109132 Ų13276%0.76278%0.779SS**  87.2128.8128.476.70000126.8
811Q30.3Very low36.5Very low184 Ų184134.2 Ų134.286%0.8678%0.778SS**  trans53.9173.7143.5-77.3-162.921.400123.3
812P51.9Low35.8Very low120 Ų120136 Ų13678%0.77978%0.776SS**  cis-136.9-180-41.338.7-21.6000115.5
813G27.7Very low35.7Very low83 Ų83138.3 Ų138.386%0.85678%0.779SS**  trans157.9150.9160.400000119.8
814N28.6Very low35.4Very low150 Ų150139 Ų13980%0.80278%0.777SS**  trans-163.3150176.6-172.215.5000111.5D816N814-D816 PolarHBondContact OD1-N 3.42Å
815P46.1Very low34.9Very low119 Ų119141.9 Ų141.977%0.77378%0.779SS**  -157.7131.1109.837.3-16.4000120.2
816D32Very low34.2Very low129 Ų129137.3 Ų137.369%0.6977%0.774SS**  trans35134.1134.6-158.58000125.1N814 T818N814-D816 PolarHBondContact OD1-N 3.42Å; D816-T818 PolarHBondContact OD1-N 2.77Å
817K28.1Very low33.4Very low199 Ų199141.7 Ų141.787%0.86578%0.78SS**  trans-163.3109.3137.2-113.7173.1-175.3176.70115.5
818T30Very low33.1Very low107 Ų107140.1 Ų140.166%0.65678%0.777SS**  trans-16.8155.8150.1570000119.3D816D816-T818 PolarHBondContact OD1-N 2.77Å
819K26Very low31.5Very low186 Ų186144.1 Ų144.181%0.80978%0.783SS**  cis-178.3-165.60.6-118.3178.8177.5178.10108.2
820P42.6Very low31.3Very low97 Ų97143.6 Ų143.663%0.6379%0.785SS**  cis-138.2-179.1-25.732-9.6000116.6
821T25.9Very low31.6Very low117 Ų117144.3 Ų144.372%0.71879%0.787SS**  trans63.5151.1145.438.50000122.1
822Q27.8Very low31.7Very low157 Ų157144.9 Ų144.973%0.73479%0.79SS**  cis-167.8164.9-18.1-142.8170.9-6.700112.2
823Q27.3Very low30.6Very low172 Ų172147.5 Ų147.580%0.80479%0.794SS**  trans76.2164.5149.9-96.1173.5-20.700123.2
824E28.3Very low30.9Very low171 Ų171150.6 Ų150.680%0.79979%0.791SS**  trans-118.2160.8-164.1-52.4153.6103.500112.3
825T26.6Very low31Very low140 Ų140151 Ų15186%0.85979%0.791SS**  168.1154.7118.833.60000115.5
826A29.4Very low30.5Very low97 Ų97156.5 Ų156.580%0.80281%0.814SS**  trans80.3159.715100000122
827E29.2Very low30.4Very low178 Ų178157.9 Ų157.983%0.83282%0.821SS**  trans101.7140.8176.1-64.2-144.5137.600117.9
828N29.6Very low30.6Very low139 Ų139155.7 Ų155.774%0.74382%0.818SS**  cis-156.2176.6-28-144.6-30.3000110.6
829K29.1Very low30.6Very low195 Ų195158.4 Ų158.485%0.84883%0.827SS**PPolyproline II helixtrans-84.3159.6-177.3-79.9-171.1173.6-170.80115.3
830L28.7Very low30.9Very low167 Ų167156.8 Ų156.887%0.87483%0.828SS**PPolyproline II helixtrans-101.9159.5165.1-77.4166.5000111.7
831P39.2Very low30.1Very low123 Ų123160.6 Ų160.680%0.79984%0.841SS**PPolyproline II helixtrans-91.2163.9-174.336.7-36.5000115.1
832E32.1Very low30.4Very low197 Ų197163.5 Ų163.592%0.92185%0.849SS**PPolyproline II helixtrans-86.8171.2173.9-69.3161.2124.200112.5
833M28.5Very low30.6Very low175 Ų175163.9 Ų163.986%0.86286%0.857SS**  trans-146.2120.2170.2-170.917975.900109.4
834D34.6Very low30.8Very low148 Ų148163.3 Ų163.379%0.79186%0.861SS**  trans-72.1161.3-179.2-57.7-70.2000113.6
835I30.5Very low31.1Very low158 Ų158162.7 Ų162.781%0.8187%0.866SS**  trans-163.9151.4137.1-97.9149.2000108.3
836D35.4Very low31.5Very low235 Ų235164.7 Ų164.7100%1.25787%0.867SS**  trans-56.40-172-52.2-85.7000116.7

Retrieved 836 of 836 residues in 735.5 ms (Link to these results)