A0A087XMX9_POEFO Loading...

Lanosterol 14-alpha demethylase

AlphaFold DB , UniProt , Accession A0A087XMX9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 497 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1K42.7Very low44.6Very low228 Ų228125.1 Ų125.199%0.99162%0.62SS**  0-34.40-77.2-176.7175.8178.90113.1
2M35.4Very low45.1Very low146 Ų146127.2 Ų127.272%0.71962%0.623SS**Hα-helixtrans-75.1-28.3177.1-121.9169.474.300115.5F6M2-F6 PolarHBondContact O-N 2.71Å
3S43.3Very low45.4Very low93 Ų93126.6 Ų126.665%0.6562%0.623SS**Hα-helixtrans-75.8-29.7-179.168.20000113.8Y7S3-Y7 PolarHBondContact O-N 3.18Å; S3-Y7 VanDerWaalsContact O-N 3.15Å
4T43.2Very low45.8Very low86 Ų86125.6 Ų125.653%0.52862%0.621SS.*Hα-helixtrans-73.3-34.6179.5-29.30000111.6Q8T4-Q8 WeakPolarHBondContact O-CB 3.17Å; T4-Q8 WeakPolarHBondContact O-CG 3.35Å; T4-Q8 PolarHBondContact O-N 3.04Å; T4-Q8 VanDerWaalsContact O-N 3.11Å
5Q42.3Very low46.1Very low130 Ų130120.1 Ų120.161%0.60761%0.609SS**Hα-helixtrans-70.7-37.9174.6-83.3179.7-33.700112.5Q8 M9Q5-Q8 PolarHBondContact O-N 2.77Å; Q5-M9 WeakPolarHBondContact O-CB 3.26Å; Q5-M9 PolarHBondContact O-N 2.89Å
6F45.4Very low46.3Very low143 Ų143118.9 Ų118.963%0.62760%0.604SS**Hα-helixtrans-65.9-40.2174.4-100-85.1000112.5M2 M9 S10M2-F6 PolarHBondContact O-N 2.71Å; F6-M9 PolarHBondContact O-N 2.71Å; F6-S10 WeakPolarHBondContact O-CB 2.8Å; F6-S10 PolarHBondContact O-N 2.57Å; F6-S10 PolarHBondContact O-OG 3.45Å
7Y46.9Very low46.8Very low166 Ų166116.2 Ų116.265%0.65160%0.595SS**Hα-helixtrans-66.9-37.2177.4-162-95.1000112.3S3 S10 T11S3-Y7 PolarHBondContact O-N 3.18Å; S3-Y7 VanDerWaalsContact O-N 3.15Å; Y7-S10 WeakPolarHBondContact CA-OG 3.47Å; Y7-S10 PolarHBondContact O-OG 3.14Å; Y7-T11 HydrophobicContact CD1-CG2 4.35Å; Y7-T11 HydrophobicContact CE1-CG2 4.13Å; Y7-T11 WeakPolarHBondContact O-CB 3.26Å; Y7-T11 WeakPolarHBondContact O-CG2 3.35Å; Y7-T11 PolarHBondContact O-N 3.04Å; Y7-T11 PolarHBondContact O-OG1 3.43Å
8Q46.5Very low47.1Very low126 Ų126117.9 Ų117.959%0.58960%0.603SS**Hα-helixtrans-71.2-36.9173.7-77.6179.1-28.700112.4T4 Q5 T11 K12T4-Q8 WeakPolarHBondContact O-CB 3.17Å; T4-Q8 WeakPolarHBondContact O-CG 3.35Å; T4-Q8 PolarHBondContact O-N 3.04Å; T4-Q8 VanDerWaalsContact O-N 3.11Å; Q5-Q8 PolarHBondContact O-N 2.77Å; Q8-T11 WeakPolarHBondContact CA-OG1 3.34Å; Q8-T11 PolarHBondContact O-OG1 2.8Å; Q8-K12 VanDerWaalsContact O-CB 3.24Å; Q8-K12 WeakPolarHBondContact O-CB 3.37Å; Q8-K12 PolarHBondContact O-N 3.1Å
9M44.7Very low47.3Very low137 Ų137115.1 Ų115.168%0.67561%0.605SS**Hα-helixtrans-67.2-41.2173.1-109.3177.975.900112Q5 F6 K12 L13Q5-M9 WeakPolarHBondContact O-CB 3.26Å; Q5-M9 PolarHBondContact O-N 2.89Å; F6-M9 PolarHBondContact O-N 2.71Å; M9-K12 PolarHBondContact O-N 2.98Å; M9-L13 VanDerWaalsContact O-CB 3.3Å; M9-L13 WeakPolarHBondContact O-CB 3.38Å; M9-L13 PolarHBondContact O-N 3.39Å
10S48.1Very low47.5Very low52 Ų52118.6 Ų118.636%0.36462%0.615SS.*Hα-helixtrans-69.4-38.3179.662.60000112.5F6 Y7 L14F6-S10 WeakPolarHBondContact O-CB 2.8Å; F6-S10 PolarHBondContact O-N 2.57Å; F6-S10 PolarHBondContact O-OG 3.45Å; Y7-S10 WeakPolarHBondContact CA-OG 3.47Å; Y7-S10 PolarHBondContact O-OG 3.14Å; S10-L14 VanDerWaalsContact O-CB 3.29Å; S10-L14 WeakPolarHBondContact O-CB 3.39Å; S10-L14 WeakPolarHBondContact O-CD1 3.33Å; S10-L14 WeakPolarHBondContact O-CG 3.38Å; S10-L14 PolarHBondContact O-N 2.89Å
11T51.8Low47.7Very low69 Ų69115 Ų11542%0.42360%0.596SS.*Hα-helixtrans-70.4-35.3175.442.10000112.2Y7 Q8 G15Y7-T11 HydrophobicContact CD1-CG2 4.35Å; Y7-T11 HydrophobicContact CE1-CG2 4.13Å; Y7-T11 WeakPolarHBondContact O-CB 3.26Å; Y7-T11 WeakPolarHBondContact O-CG2 3.35Å; Y7-T11 PolarHBondContact O-N 3.04Å; Y7-T11 PolarHBondContact O-OG1 3.43Å; Q8-T11 WeakPolarHBondContact CA-OG1 3.34Å; Q8-T11 PolarHBondContact O-OG1 2.8Å; T11-G15 PolarHBondContact O-N 3.28Å
12K50.5Low48.1Very low150 Ų150110.9 Ų110.965%0.65259%0.585SS**Hα-helixtrans-70.9-40.3174.3-154.3175.6-171.7-176.10112Q8 M9 G15 D16Q8-K12 VanDerWaalsContact O-CB 3.24Å; Q8-K12 WeakPolarHBondContact O-CB 3.37Å; Q8-K12 PolarHBondContact O-N 3.1Å; M9-K12 PolarHBondContact O-N 2.98Å; K12-G15 PolarHBondContact O-N 2.71Å; K12-D16 WeakPolarHBondContact O-CB 3.15Å; K12-D16 VanDerWaalsContact O-CG 3.31Å; K12-D16 PolarHBondContact O-N 2.82Å
13L49.1Very low49Very low120 Ų120113 Ų11363%0.62859%0.593SS**Hα-helixtrans-64.4-43.5173.8-153.685.2000111.2M9 T17M9-L13 VanDerWaalsContact O-CB 3.3Å; M9-L13 WeakPolarHBondContact O-CB 3.38Å; M9-L13 PolarHBondContact O-N 3.39Å; L13-T17 VanDerWaalsContact O-CB 3.28Å; L13-T17 WeakPolarHBondContact O-CB 3.33Å; L13-T17 PolarHBondContact O-N 2.95Å; L13-T17 PolarHBondContact O-OG1 3.46Å
14L51.9Low49.8Very low113 Ų113113.1 Ų113.159%0.59259%0.587SS**Hα-helixtrans-64.5-40.3174.6-81.2161.3000112.1S10 T17 M18S10-L14 VanDerWaalsContact O-CB 3.29Å; S10-L14 WeakPolarHBondContact O-CB 3.39Å; S10-L14 WeakPolarHBondContact O-CD1 3.33Å; S10-L14 WeakPolarHBondContact O-CG 3.38Å; S10-L14 PolarHBondContact O-N 2.89Å; L14-T17 PolarHBondContact O-N 3.02Å; L14-M18 WeakPolarHBondContact O-CB 3.28Å; L14-M18 WeakPolarHBondContact O-CG 3.34Å; L14-M18 PolarHBondContact O-N 2.83Å
15G49.2Very low51Low42 Ų42115.8 Ų115.843%0.43360%0.597SS.*Hα-helixtrans-65.2-44.4175.700000113.1T11 K12 T17 M18 G19T11-G15 PolarHBondContact O-N 3.28Å; K12-G15 PolarHBondContact O-N 2.71Å; G15-T17 VanDerWaalsContact C-N 3.34Å; G15-M18 PolarHBondContact O-N 3.11Å; G15-G19 PolarHBondContact O-N 2.91Å
16D50.3Low52Low101 Ų101113.7 Ų113.754%0.5459%0.593SS.*Hα-helixtrans-71.3-30178.2-73.5-18.7000112.2K12 K20K12-D16 WeakPolarHBondContact O-CB 3.15Å; K12-D16 VanDerWaalsContact O-CG 3.31Å; K12-D16 PolarHBondContact O-N 2.82Å; D16-K20 PolarHBondContact O-N 2.97Å
17T54.3Low53.1Low73 Ų73109.3 Ų109.345%0.44858%0.58SS.*Hα-helixtrans-76.4-40.9175.3-46.50000110.9L13 L14 G15 K20 M21L13-T17 VanDerWaalsContact O-CB 3.28Å; L13-T17 WeakPolarHBondContact O-CB 3.33Å; L13-T17 PolarHBondContact O-N 2.95Å; L13-T17 PolarHBondContact O-OG1 3.46Å; L14-T17 PolarHBondContact O-N 3.02Å; G15-T17 VanDerWaalsContact C-N 3.34Å; T17-K20 PolarHBondContact O-N 3.03Å; T17-M21 HydrophobicContact CG2-SD 4.13Å; T17-M21 WeakPolarHBondContact O-CB 3.45Å; T17-M21 WeakPolarHBondContact O-CG 3.44Å; T17-M21 PolarHBondContact O-N 2.95Å
18M51.6Low54.2Low148 Ų148105.7 Ų105.773%0.72957%0.572SS**Hα-helixtrans-68.4-34.6174.6-78.9-164.4126.400112.7L14 G15 K20 M21L14-M18 WeakPolarHBondContact O-CB 3.28Å; L14-M18 WeakPolarHBondContact O-CG 3.34Å; L14-M18 PolarHBondContact O-N 2.83Å; G15-M18 PolarHBondContact O-N 3.11Å; M18-K20 VanDerWaalsContact C-N 3.27Å; M18-K20 PolarHBondContact O-N 3.18Å; M18-M21 PolarHBondContact O-N 2.89Å
19G50.7Low55.4Low63 Ų63103.6 Ų103.665%0.64957%0.567SS**Hα-helixtrans-66.4-25.1175.600000114.1G15G15-G19 PolarHBondContact O-N 2.91Å
20K51.5Low56.7Low185 Ų185102.9 Ų102.980%0.80457%0.565SS**Hα-helixtrans-96.2-7.1177.1-72.9-177.51781790114.4D16 T17 M18D16-K20 PolarHBondContact O-N 2.97Å; T17-K20 PolarHBondContact O-N 3.03Å; M18-K20 VanDerWaalsContact C-N 3.27Å; M18-K20 PolarHBondContact O-N 3.18Å
21M51.5Low57.9Low43 Ų43102.4 Ų102.421%0.21256%0.564CS.*  trans-92.59.6-175-84.8-175.679.500114.5T17 M18 E23 S27 L28 A31T17-M21 HydrophobicContact CG2-SD 4.13Å; T17-M21 WeakPolarHBondContact O-CB 3.45Å; T17-M21 WeakPolarHBondContact O-CG 3.44Å; T17-M21 PolarHBondContact O-N 2.95Å; M18-M21 PolarHBondContact O-N 2.89Å; M21-E23 PolarHBondContact O-N 3.15Å; M21-S27 WeakPolarHBondContact CE-O 3.49Å; M21-L28 WeakPolarHBondContact O-CD1 3.45Å; M21-A31 HydrophobicContact CE-CB 3.27Å; M21-A31 HydrophobicContact SD-CB 4.17Å
22N51.6Low58.8Low142 Ų142101.7 Ų101.776%0.75957%0.565SS**THydrogen-bonded Turntrans-88.36.8-171.7-142.222000115.2
23E54.6Low59.9Low190 Ų19097 Ų9789%0.88855%0.552SS**THydrogen-bonded Turntrans-117.71.9-175.5-70.3-164.6168.700115.7M21M21-E23 PolarHBondContact O-N 3.15Å
24N61Low61.4Low97 Ų9797 Ų9752%0.51955%0.552SS.*  trans-147.2114.9174.7-130.7-23.7000112.8T26 S27 L28N24-T26 PolarHBondContact O-N 3.39Å; N24-T26 VanDerWaalsContact O-N 3.15Å; N24-T26 PolarHBondContact OD1-OG1 3.35Å; N24-S27 WeakPolarHBondContact O-CB 3.47Å; N24-S27 PolarHBondContact O-N 2.95Å; N24-L28 PolarHBondContact O-N 3.19Å
25L66.5Low62.8Low142 Ų14298.1 Ų98.174%0.74355%0.552SS**Hα-helixtrans-54.5-33.6179.2-173.867.4000111.7L28 V29L25-L28 PolarHBondContact O-N 3.26Å; L25-V29 WeakPolarHBondContact O-CB 3.36Å; L25-V29 WeakPolarHBondContact O-CG2 3.49Å; L25-V29 PolarHBondContact O-N 3.2Å
26T65.2Low64Low86 Ų86100.3 Ų100.353%0.52856%0.557SS.*Hα-helixtrans-63.1-42.6175.441.30000112.9N24 V29 L30N24-T26 PolarHBondContact O-N 3.39Å; N24-T26 VanDerWaalsContact O-N 3.15Å; N24-T26 PolarHBondContact OD1-OG1 3.35Å; T26-V29 PolarHBondContact O-N 2.62Å; T26-L30 WeakPolarHBondContact O-CB 3.2Å; T26-L30 WeakPolarHBondContact O-CG 3.15Å; T26-L30 PolarHBondContact O-N 3.07Å
27S67.6Low65.4Low51 Ų51101.3 Ų101.336%0.35756%0.562SS.*Hα-helixtrans-65.2-41.7177.3-51.10000111.4M21 N24 L30 A31M21-S27 WeakPolarHBondContact CE-O 3.49Å; N24-S27 WeakPolarHBondContact O-CB 3.47Å; N24-S27 PolarHBondContact O-N 2.95Å; S27-L30 PolarHBondContact O-N 3.04Å; S27-A31 PolarHBondContact O-N 3.44Å
28L70Confident66.4Low90 Ų90101.3 Ų101.347%0.47156%0.562SS.*Hα-helixtrans-67.1-42.1179.8-142.5119.9000111.4M21 N24 L25 A31 A32M21-L28 WeakPolarHBondContact O-CD1 3.45Å; N24-L28 PolarHBondContact O-N 3.19Å; L25-L28 PolarHBondContact O-N 3.26Å; L28-A31 PolarHBondContact O-N 3.33Å; L28-A32 VanDerWaalsContact O-CB 3.29Å; L28-A32 WeakPolarHBondContact O-CB 3.3Å; L28-A32 PolarHBondContact O-N 2.92Å
29V71.6Confident67.5Low82 Ų8299.2 Ų99.250%0.49755%0.553SS.*Hα-helixtrans-63.9-42.6173.8170.90000111.2L25 T26 S33L25-V29 WeakPolarHBondContact O-CB 3.36Å; L25-V29 WeakPolarHBondContact O-CG2 3.49Å; L25-V29 PolarHBondContact O-N 3.2Å; T26-V29 PolarHBondContact O-N 2.62Å; V29-S33 VanDerWaalsContact O-CB 3.24Å; V29-S33 WeakPolarHBondContact O-CB 3.24Å; V29-S33 PolarHBondContact O-N 3.23Å; V29-S33 PolarHBondContact O-OG 3.44Å
30L72.6Confident68.6Low122 Ų12298.2 Ų98.264%0.63954%0.542SS*.Hα-helixtrans-63.5-44.7177.6-85.7161.1000112.2T26 S27 S33 L34T26-L30 WeakPolarHBondContact O-CB 3.2Å; T26-L30 WeakPolarHBondContact O-CG 3.15Å; T26-L30 PolarHBondContact O-N 3.07Å; S27-L30 PolarHBondContact O-N 3.04Å; L30-S33 PolarHBondContact O-N 2.87Å; L30-L34 WeakPolarHBondContact O-CB 3.41Å; L30-L34 PolarHBondContact O-N 2.83Å
31A73.1Confident69.6Low41 Ų4196.3 Ų96.334%0.33953%0.531SS..Hα-helixtrans-69.3-40.6178.600000112.5M21 S27 L28 S33 L34 F35M21-A31 HydrophobicContact CE-CB 3.27Å; M21-A31 HydrophobicContact SD-CB 4.17Å; S27-A31 PolarHBondContact O-N 3.44Å; L28-A31 PolarHBondContact O-N 3.33Å; A31-S33 VanDerWaalsContact C-N 3.32Å; A31-S33 PolarHBondContact O-N 3.34Å; A31-L34 PolarHBondContact O-N 3.22Å; A31-F35 VanDerWaalsContact O-CB 3.32Å; A31-F35 WeakPolarHBondContact O-CB 3.49Å; A31-F35 PolarHBondContact O-N 3.17Å
32A71.4Confident70.5Confident54 Ų5497.7 Ų97.745%0.44654%0.542SS..Hα-helixtrans-63.2-40174.200000111.5L28 F35 T36L28-A32 VanDerWaalsContact O-CB 3.29Å; L28-A32 WeakPolarHBondContact O-CB 3.3Å; L28-A32 PolarHBondContact O-N 2.92Å; A32-F35 PolarHBondContact O-N 3.49Å; A32-T36 WeakPolarHBondContact O-CB 3.35Å; A32-T36 WeakPolarHBondContact O-CG2 3.5Å; A32-T36 PolarHBondContact O-N 2.7Å; A32-T36 PolarHBondContact O-OG1 2.87Å
33S72.6Confident71Confident53 Ų5393.5 Ų93.537%0.37152%0.524SS..Hα-helixtrans-64.7-44174.6-58.10000111.6V29 L30 A31 T36 L37V29-S33 VanDerWaalsContact O-CB 3.24Å; V29-S33 WeakPolarHBondContact O-CB 3.24Å; V29-S33 PolarHBondContact O-N 3.23Å; V29-S33 PolarHBondContact O-OG 3.44Å; L30-S33 PolarHBondContact O-N 2.87Å; A31-S33 VanDerWaalsContact C-N 3.32Å; A31-S33 PolarHBondContact O-N 3.34Å; S33-T36 WeakPolarHBondContact CA-OG1 3.38Å; S33-T36 PolarHBondContact O-OG1 3.34Å; S33-L37 VanDerWaalsContact O-CB 3.27Å; S33-L37 WeakPolarHBondContact O-CB 3.42Å; S33-L37 WeakPolarHBondContact O-CD1 3.41Å; S33-L37 WeakPolarHBondContact O-CG 3.3Å; S33-L37 PolarHBondContact O-N 2.85Å
34L80.2Confident71.4Confident119 Ų11991.2 Ų91.262%0.62351%0.511SS*.Hα-helixtrans-64-44.3177.4-161.576000111L30 A31 L37 T38L30-L34 WeakPolarHBondContact O-CB 3.41Å; L30-L34 PolarHBondContact O-N 2.83Å; A31-L34 PolarHBondContact O-N 3.22Å; L34-L37 PolarHBondContact O-N 3.43Å; L34-T38 PolarHBondContact O-N 3.01Å; L34-T38 PolarHBondContact O-OG1 3.22Å
35F81.7Confident71.4Confident136 Ų13695.2 Ų95.260%0.59652%0.519SS*.Hα-helixtrans-63-47.2179-170.6-98.9000111.8A31 A32 T38 L39A31-F35 VanDerWaalsContact O-CB 3.32Å; A31-F35 WeakPolarHBondContact O-CB 3.49Å; A31-F35 PolarHBondContact O-N 3.17Å; A32-F35 PolarHBondContact O-N 3.49Å; F35-T38 VanDerWaalsContact CA-OG1 3.26Å; F35-T38 WeakPolarHBondContact CA-OG1 3.12Å; F35-T38 PolarHBondContact O-N 3.21Å; F35-T38 PolarHBondContact O-OG1 2.84Å; F35-L39 WeakPolarHBondContact O-CB 3.38Å; F35-L39 PolarHBondContact O-N 2.9Å
36T75Confident70.7Confident88 Ų8895.1 Ų95.154%0.5452%0.518SS..Hα-helixtrans-64.4-38.6176.548.40000112.4A32 S33 L39 G40A32-T36 WeakPolarHBondContact O-CB 3.35Å; A32-T36 WeakPolarHBondContact O-CG2 3.5Å; A32-T36 PolarHBondContact O-N 2.7Å; A32-T36 PolarHBondContact O-OG1 2.87Å; S33-T36 WeakPolarHBondContact CA-OG1 3.38Å; S33-T36 PolarHBondContact O-OG1 3.34Å; T36-L39 PolarHBondContact O-N 3Å; T36-G40 PolarHBondContact O-N 3.28Å
37L78.2Confident70Confident123 Ų12397.3 Ų97.364%0.64453%0.526SS*.Hα-helixtrans-65.9-41.7173.7-74.6168.9000111.9S33 L34 G40 Y41S33-L37 VanDerWaalsContact O-CB 3.27Å; S33-L37 WeakPolarHBondContact O-CB 3.42Å; S33-L37 WeakPolarHBondContact O-CD1 3.41Å; S33-L37 WeakPolarHBondContact O-CG 3.3Å; S33-L37 PolarHBondContact O-N 2.85Å; L34-L37 PolarHBondContact O-N 3.43Å; L37-G40 PolarHBondContact O-N 2.91Å; L37-Y41 VanDerWaalsContact O-CB 3.3Å; L37-Y41 WeakPolarHBondContact O-CB 3.38Å; L37-Y41 PolarHBondContact O-N 3.08Å
38T77.1Confident69.2Low72 Ų72100.7 Ų100.744%0.44253%0.534SS..Hα-helixtrans-66.5-40.8174.539.90000112.2L34 F35 Y41 V42L34-T38 PolarHBondContact O-N 3.01Å; L34-T38 PolarHBondContact O-OG1 3.22Å; F35-T38 VanDerWaalsContact CA-OG1 3.26Å; F35-T38 WeakPolarHBondContact CA-OG1 3.12Å; F35-T38 PolarHBondContact O-N 3.21Å; F35-T38 PolarHBondContact O-OG1 2.84Å; T38-Y41 PolarHBondContact O-N 3.22Å; T38-V42 WeakPolarHBondContact O-CB 3.42Å; T38-V42 VanDerWaalsContact O-CG2 3.27Å; T38-V42 WeakPolarHBondContact O-CG2 3.23Å; T38-V42 PolarHBondContact O-N 3.37Å
39L74.6Confident68.2Low105 Ų105104.6 Ų104.655%0.5555%0.55SS.*Hα-helixtrans-66.7-40.2177.1-162.675.6000110.6F35 T36 S43F35-L39 WeakPolarHBondContact O-CB 3.38Å; F35-L39 PolarHBondContact O-N 2.9Å; T36-L39 PolarHBondContact O-N 3Å; L39-S43 WeakPolarHBondContact O-CB 3.19Å; L39-S43 PolarHBondContact O-N 3.4Å
40G72.3Confident67Low41 Ų41106.4 Ų106.442%0.42357%0.566SS.*Hα-helixtrans-63.9-40172.500000112.7T36 L37 K44T36-G40 PolarHBondContact O-N 3.28Å; L37-G40 PolarHBondContact O-N 2.91Å; G40-K44 WeakPolarHBondContact O-CB 3.2Å; G40-K44 PolarHBondContact O-N 3.39Å
41Y73.8Confident66.2Low145 Ų145105 Ų10557%0.56956%0.556SS**Hα-helixtrans-66-47.5175.4178.5-98000112L37 T38 K44 R45L37-Y41 VanDerWaalsContact O-CB 3.3Å; L37-Y41 WeakPolarHBondContact O-CB 3.38Å; L37-Y41 PolarHBondContact O-N 3.08Å; T38-Y41 PolarHBondContact O-N 3.22Å; Y41-K44 PolarHBondContact O-N 3.41Å; Y41-R45 WeakPolarHBondContact O-CB 3.42Å; Y41-R45 PolarHBondContact O-N 2.91Å
42V70.6Confident65.6Low73 Ų73107.6 Ų107.644%0.44257%0.565SS.*Hα-helixtrans-66.1-44.2178.2171.80000110.7T38 K44 R45 L46T38-V42 WeakPolarHBondContact O-CB 3.42Å; T38-V42 VanDerWaalsContact O-CG2 3.27Å; T38-V42 WeakPolarHBondContact O-CG2 3.23Å; T38-V42 PolarHBondContact O-N 3.37Å; V42-K44 PolarHBondContact O-N 3.03Å; V42-R45 CarbonylContact O-C 3.59Å; V42-R45 WeakPolarHBondContact O-CB 3.25Å; V42-R45 PolarHBondContact O-N 2.92Å; V42-R45 VanDerWaalsContact O-N 3.09Å; V42-L46 HydrophobicContact CG1-CD1 3.69Å; V42-L46 HydrophobicContact CG1-CG 4.29Å; V42-L46 WeakPolarHBondContact O-CB 3.43Å; V42-L46 VanDerWaalsContact O-CG 3.29Å; V42-L46 WeakPolarHBondContact O-CG 3.42Å; V42-L46 PolarHBondContact O-N 3.37Å
43S62.2Low65.1Low53 Ų53114.6 Ų114.637%0.37159%0.585SS.*Hα-helixtrans-61.6-43.2175.6-171.90000111.3L39 R45 L46 L47L39-S43 WeakPolarHBondContact O-CB 3.19Å; L39-S43 PolarHBondContact O-N 3.4Å; S43-R45 VanDerWaalsContact C-N 3.28Å; S43-R45 PolarHBondContact O-N 2.89Å; S43-L46 PolarHBondContact O-N 2.72Å; S43-L47 WeakPolarHBondContact O-CB 3.11Å; S43-L47 WeakPolarHBondContact O-CG 3.48Å; S43-L47 PolarHBondContact O-N 2.63Å; S43-L47 WeakPolarHBondContact OG-CD1 3.5Å
44K61.8Low65.1Low142 Ų142119.3 Ų119.362%0.61761%0.606SS**Hα-helixtrans-63.3-31.8173.1-174.1175.3-179178.60112.9G40 Y41 V42 K48G40-K44 WeakPolarHBondContact O-CB 3.2Å; G40-K44 PolarHBondContact O-N 3.39Å; Y41-K44 PolarHBondContact O-N 3.41Å; V42-K44 PolarHBondContact O-N 3.03Å; K44-K48 PolarHBondContact O-N 3.5Å
45R61.2Low65.2Low181 Ų181114.6 Ų114.668%0.68358%0.584SS**Hα-helixtrans-75.2-32176.3-138.8-175.4-178.4-174.21112.4Y41 V42 S43Y41-R45 WeakPolarHBondContact O-CB 3.42Å; Y41-R45 PolarHBondContact O-N 2.91Å; V42-R45 CarbonylContact O-C 3.59Å; V42-R45 WeakPolarHBondContact O-CB 3.25Å; V42-R45 PolarHBondContact O-N 2.92Å; V42-R45 VanDerWaalsContact O-N 3.09Å; S43-R45 VanDerWaalsContact C-N 3.28Å; S43-R45 PolarHBondContact O-N 2.89Å
46L51.8Low65.8Low141 Ų141114.4 Ų114.474%0.73858%0.583SS**Hα-helixtrans-84.3-33.3178.3-69.1169.9000112.9V42 S43 K48V42-L46 HydrophobicContact CG1-CD1 3.69Å; V42-L46 HydrophobicContact CG1-CG 4.29Å; V42-L46 WeakPolarHBondContact O-CB 3.43Å; V42-L46 VanDerWaalsContact O-CG 3.29Å; V42-L46 WeakPolarHBondContact O-CG 3.42Å; V42-L46 PolarHBondContact O-N 3.37Å; S43-L46 PolarHBondContact O-N 2.72Å; L46-K48 VanDerWaalsContact C-N 3.25Å
47L50.3Low66.8Low131 Ų131113.8 Ų113.869%0.68657%0.572SS**SBendtrans-85.16.7173.9-71.7166.2000112.8S43 E49S43-L47 WeakPolarHBondContact O-CB 3.11Å; S43-L47 WeakPolarHBondContact O-CG 3.48Å; S43-L47 PolarHBondContact O-N 2.63Å; S43-L47 WeakPolarHBondContact OG-CD1 3.5Å; L47-E49 PolarHBondContact O-N 2.94Å
48K50.7Low67.7Low122 Ų122108.4 Ų108.453%0.5354%0.544SS..  trans-6693.2168.9-157.5-179.7-167.4-153.10105.9K44 L46 S50 E51K44-K48 PolarHBondContact O-N 3.5Å; L46-K48 VanDerWaalsContact C-N 3.25Å; K48-S50 PolarHBondContact O-N 3.01Å; K48-E51 WeakPolarHBondContact CE-OE1 3.46Å; K48-E51 WeakPolarHBondContact CE-OE2 3.4Å; K48-E51 IonicContact NZ-OE1 2.76Å; K48-E51 PolarHBondContact NZ-OE1 2.62Å; K48-E51 IonicContact NZ-OE2 3.61Å; K48-E51 PolarHBondContact NZ-OE2 2.99Å
49E49.1Very low68.7Low173 Ų173106.6 Ų106.681%0.80853%0.533SS*.  trans-40.9136.4168.6-102.2177.3162.100108.1L47 E51L47-E49 PolarHBondContact O-N 2.94Å; E49-E51 VanDerWaalsContact C-N 3.31Å; E49-E51 PolarHBondContact O-N 3.19Å
50S46.8Very low69.8Low119 Ų119106.9 Ų106.983%0.83253%0.528SS*.  trans-37.393173.4162.80000110.5K48 D52K48-S50 PolarHBondContact O-N 3.01Å; S50-D52 PolarHBondContact O-N 3.31Å; S50-D52 VanDerWaalsContact O-N 3.09Å
51E55.8Low71Confident92 Ų92105.6 Ų105.643%0.4351%0.511SS..  trans-57.3119.6168.9-82.2177.4163.500105.6K48 E49 K53 Y57K48-E51 WeakPolarHBondContact CE-OE1 3.46Å; K48-E51 WeakPolarHBondContact CE-OE2 3.4Å; K48-E51 IonicContact NZ-OE1 2.76Å; K48-E51 PolarHBondContact NZ-OE1 2.62Å; K48-E51 IonicContact NZ-OE2 3.61Å; K48-E51 PolarHBondContact NZ-OE2 2.99Å; E49-E51 VanDerWaalsContact C-N 3.31Å; E49-E51 PolarHBondContact O-N 3.19Å; E51-K53 PolarHBondContact O-N 3.43Å; E51-Y57 WeakPolarHBondContact CA-OH 3.46Å; E51-Y57 HydrophobicContact CB-CE2 4.14Å; E51-Y57 WeakPolarHBondContact CB-OH 3.34Å; E51-Y57 HydrophobicContact CG-CE2 4.19Å
52D59.6Low72Confident96 Ų96103 Ų10351%0.51351%0.512SS..  trans-55.7113.7175.1-175.3-3.4000107.3S50 D54 A55 Y57S50-D52 PolarHBondContact O-N 3.31Å; S50-D52 VanDerWaalsContact O-N 3.09Å; D52-D54 PolarHBondContact O-N 3.46Å; D52-D54 VanDerWaalsContact O-N 3.07Å; D52-D54 PolarHBondContact OD1-N 3.39Å; D52-A55 HydrophobicContact CB-CB 3.97Å; D52-A55 WeakPolarHBondContact O-CB 3.29Å; D52-A55 PolarHBondContact O-N 2.9Å; D52-Y57 PolarHBondContact N-OH 3.05Å
53K61.1Low73.2Confident201 Ų201101.6 Ų101.687%0.87451%0.506SS*.THydrogen-bonded Turntrans-63-18.4-172.7-74.9-176.4177.7177.50112.1E51E51-K53 PolarHBondContact O-N 3.43Å
54D73.5Confident74.6Confident153 Ų153104.8 Ų104.882%0.81853%0.528SS*.THydrogen-bonded Turntrans-95.1-8.4-179.9-61.7-31.6000112.9D52D52-D54 PolarHBondContact O-N 3.46Å; D52-D54 VanDerWaalsContact O-N 3.07Å; D52-D54 PolarHBondContact OD1-N 3.39Å
55A81.4Confident76Confident20 Ų20101.9 Ų101.917%0.16552%0.518CS..  trans-79.3126.3-179.800000112.1D52 Y57D52-A55 HydrophobicContact CB-CB 3.97Å; D52-A55 WeakPolarHBondContact O-CB 3.29Å; D52-A55 PolarHBondContact O-N 2.9Å; A55-Y57 HydrophobicContact CB-CE1 4.36Å; A55-Y57 HydrophobicContact CB-CE2 4.33Å; A55-Y57 PolarHBondContact O-N 3.24Å
56K94.3Very high77.2Confident131 Ų13198.8 Ų98.857%0.5752%0.521SS*.  trans-83.7102.8175-167.7-178.2178.1-177.50109.9Y390 T391K56-Y390 HydrophobicContact CD-CD1 4.13Å; K56-Y390 HydrophobicContact CD-CE1 4.01Å; K56-Y390 HydrophobicContact CG-CD1 3.83Å; K56-Y390 HydrophobicContact CG-CE1 3.96Å; K56-Y390 CarbonylContact O-C 3.58Å; K56-Y390 WeakPolarHBondContact O-CA 3.31Å; K56-T391 PolarHBondContact O-N 2.84Å
57Y95.9Very high79Confident76 Ų7698.7 Ų98.730%0.29852%0.515SS..PPolyproline II helixtrans-78.3152.5177.3-61.9-69.9000112.6E51 D52 A55 Y390 T391 P393E51-Y57 WeakPolarHBondContact CA-OH 3.46Å; E51-Y57 HydrophobicContact CB-CE2 4.14Å; E51-Y57 WeakPolarHBondContact CB-OH 3.34Å; E51-Y57 HydrophobicContact CG-CE2 4.19Å; D52-Y57 PolarHBondContact N-OH 3.05Å; A55-Y57 HydrophobicContact CB-CE1 4.36Å; A55-Y57 HydrophobicContact CB-CE2 4.33Å; A55-Y57 PolarHBondContact O-N 3.24Å; Y57-Y390 VanDerWaalsContact C-CD1 3.47Å; Y57-Y390 WeakPolarHBondContact O-CD1 3.29Å; Y57-Y390 WeakPolarHBondContact O-CE1 3.48Å; Y57-T391 WeakPolarHBondContact CD1-O 3.38Å; Y57-P393 HydrophobicContact CD1-CG 4.43Å; Y57-P393 HydrophobicContact CE1-CB 4.36Å; Y57-P393 HydrophobicContact CE1-CG 4.36Å
58P97.5Very high80.8Confident10 Ų1095 Ų957%0.06550%0.496CS..PPolyproline II helixtrans-54145.2172.4-26.434.2000112.1Y60 V92 T103 Y390 T391 I392P58-Y60 PolarHBondContact O-N 2.97Å; P58-V92 HydrophobicContact CB-CG1 4.07Å; P58-V92 HydrophobicContact CG-CG1 4.01Å; P58-T103 HydrophobicContact CB-CG2 4.43Å; P58-T103 HydrophobicContact CG-CG2 4.06Å; P58-Y390 HydrophobicContact CG-CG 4.41Å; P58-T391 WeakPolarHBondContact CD-O 3.34Å; P58-I392 HydrophobicContact CG-CG1 4.2Å
59P97.8Very high82.9Confident33 Ų3389.6 Ų89.621%0.21447%0.474CS..PPolyproline II helixtrans-55.3128.3172.423.1-33.4000110.5Y89 V92 F93 S94P59-Y89 HydrophobicContact CB-CD1 3.82Å; P59-Y89 HydrophobicContact CB-CG 4.48Å; P59-Y89 HydrophobicContact CG-CD1 4.4Å; P59-V92 VanDerWaalsContact CD-O 3.27Å; P59-V92 WeakPolarHBondContact CD-O 3.32Å; P59-V92 WeakPolarHBondContact CG-O 3.2Å; P59-F93 HydrophobicContact CG-CB 4.11Å; P59-F93 WeakPolarHBondContact O-CA 3.44Å; P59-S94 PolarHBondContact O-N 3.31Å
60Y97.9Very high85Confident111 Ų11182.8 Ų82.844%0.43544%0.443SS..BIsolated β-bridgetrans-99.9125.3-178-174.3-85.2000110.9P58 P62 S94 T96 T101P58-Y60 PolarHBondContact O-N 2.97Å; Y60-P62 VanDerWaalsContact O-CD 3.28Å; Y60-P62 WeakPolarHBondContact O-CD 3.47Å; Y60-S94 CarbonylContact C-O 3.46Å; Y60-S94 VanDerWaalsContact CA-O 3.31Å; Y60-S94 WeakPolarHBondContact CA-O 3.5Å; Y60-T96 WeakPolarHBondContact OH-CB 3.45Å; Y60-T96 PolarHBondContact OH-OG1 2.85Å; Y60-T101 HydrophobicContact CE2-CG2 4.16Å
61I97.8Very high87.1Confident14 Ų1478.1 Ų78.17%0.07241%0.412CS..  trans-77.8111.1179.9-49.3-179.6000109.1H70 F81 A85 Y89 F93 S94 F95I61-H70 PolarHBondContact O-NE2 2.93Å; I61-H70 VanDerWaalsContact O-NE2 3.16Å; I61-F81 HydrophobicContact CD1-CE1 4.3Å; I61-F81 HydrophobicContact CD1-CZ 4.17Å; I61-A85 HydrophobicContact CD1-CB 3.7Å; I61-Y89 HydrophobicContact CB-CE2 4.44Å; I61-Y89 HydrophobicContact CD1-CD2 4.12Å; I61-Y89 HydrophobicContact CD1-CE2 4.12Å; I61-Y89 HydrophobicContact CG1-CD2 3.93Å; I61-Y89 HydrophobicContact CG1-CE2 3.75Å; I61-Y89 HydrophobicContact CG2-CE2 4.18Å; I61-F93 HydrophobicContact CD1-CD2 3.73Å; I61-F93 HydrophobicContact CD1-CE2 4.12Å; I61-F93 HydrophobicContact CD1-CG 4.44Å; I61-F93 HydrophobicContact CG1-CD2 4.42Å; I61-S94 PolarHBondContact N-O 2.9Å; I61-F95 HydrophobicContact CB-CB 3.96Å; I61-F95 HydrophobicContact CD1-CB 4.23Å; I61-F95 HydrophobicContact CD1-CD1 4.28Å; I61-F95 HydrophobicContact CG1-CB 4.24Å
62P95.6Very high88.8Confident91 Ų9179.2 Ų79.259%0.59142%0.419SS*.  trans-65.4144-177.428.5-34.6000111Y60 H70Y60-P62 VanDerWaalsContact O-CD 3.28Å; Y60-P62 WeakPolarHBondContact O-CD 3.47Å; P62-H70 PolarHBondContact O-CE1 3.25Å; P62-H70 PolarHBondContact O-NE2 2.89Å; P62-H70 VanDerWaalsContact O-NE2 3.08Å
63S94.3Very high90.4Very high44 Ų4477 Ų7731%0.30841%0.414SS..  trans-126.4140.2170176.10000109.6I65 G69S63-I65 VanDerWaalsContact C-N 3.29Å; S63-I65 PolarHBondContact OG-N 3.35Å; S63-I65 VanDerWaalsContact OG-N 3.15Å; S63-G69 VanDerWaalsContact OG-C 3.32Å; S63-G69 WeakPolarHBondContact OG-CA 3.17Å; S63-G69 PolarHBondContact OG-O 3.25Å
64S92Very high91.9Very high119 Ų11968.5 Ų68.583%0.83238%0.377SS*.SBendtrans-79.2-10.3173.954.50000113.3P66S64-P66 WeakPolarHBondContact O-CD 3.2Å
65I91.4Very high92.6Very high81 Ų8163 Ų6342%0.41536%0.356SS..SBendtrans-106.5104-178-50.8178.3000109.1S63 L68 G69S63-I65 VanDerWaalsContact C-N 3.29Å; S63-I65 PolarHBondContact OG-N 3.35Å; S63-I65 VanDerWaalsContact OG-N 3.15Å; I65-L68 HydrophobicContact CG2-CB 3.79Å; I65-L68 HydrophobicContact CG2-CD2 4.25Å; I65-G69 WeakPolarHBondContact O-CA 3.25Å; I65-G69 PolarHBondContact O-N 2.84Å
66P86.9Confident93Very high116 Ų11670.1 Ų70.175%0.75338%0.384SS*.THydrogen-bonded Turntrans-57.6150.6176.8-22.733.6000111.6S64 L68S64-P66 WeakPolarHBondContact O-CD 3.2Å; P66-L68 PolarHBondContact O-N 3.26Å
67F88.6Confident92.9Very high140 Ų14065.3 Ų65.361%0.61437%0.366SS*.THydrogen-bonded Turntrans63.1-60.3-178.2178.6-95.7000114.9G69 V98 G99F67-G69 VanDerWaalsContact C-N 3.25Å; F67-G69 PolarHBondContact O-N 3.08Å; F67-V98 HydrophobicContact CE1-CG1 3.63Å; F67-V98 HydrophobicContact CZ-CG1 3.64Å; F67-V98 CarbonylContact O-C 3.55Å; F67-V98 WeakPolarHBondContact O-CA 3.36Å; F67-V98 PolarHBondContact O-N 3.32Å; F67-V98 VanDerWaalsContact O-N 3.15Å; F67-G99 PolarHBondContact O-N 2.99Å
68L88.4Confident92.8Very high54 Ų5461.8 Ų61.828%0.28335%0.353SS..THydrogen-bonded Turntrans-62-36.9-179.7-170.363.4000111.5I65 P66 H70 A71 I72 M97 V98I65-L68 HydrophobicContact CG2-CB 3.79Å; I65-L68 HydrophobicContact CG2-CD2 4.25Å; P66-L68 PolarHBondContact O-N 3.26Å; L68-H70 PolarHBondContact O-N 3.43Å; L68-A71 HydrophobicContact CD1-CB 3.65Å; L68-A71 HydrophobicContact CG-CB 4.05Å; L68-A71 WeakPolarHBondContact O-CB 3.37Å; L68-A71 PolarHBondContact O-N 2.94Å; L68-I72 HydrophobicContact CD2-CD1 3.73Å; L68-I72 HydrophobicContact CD2-CG1 3.95Å; L68-M97 WeakPolarHBondContact O-CA 3.47Å; L68-V98 HydrophobicContact CD1-CG2 4.38Å; L68-V98 PolarHBondContact O-N 3.45Å
69G94.3Very high92.7Very high7 Ų761.5 Ų61.57%0.07235%0.351CS..BIsolated β-bridgetrans61.6-120177.700000111.2S63 I65 F67 T96S63-G69 VanDerWaalsContact OG-C 3.32Å; S63-G69 WeakPolarHBondContact OG-CA 3.17Å; S63-G69 PolarHBondContact OG-O 3.25Å; I65-G69 WeakPolarHBondContact O-CA 3.25Å; I65-G69 PolarHBondContact O-N 2.84Å; F67-G69 VanDerWaalsContact C-N 3.25Å; F67-G69 PolarHBondContact O-N 3.08Å; G69-T96 CarbonylContact C-O 3.26Å; G69-T96 WeakPolarHBondContact CA-O 3.42Å
70H95Very high92.7Very high30 Ų3065.3 Ų65.314%0.13937%0.366CS..THydrogen-bonded Turntrans-103.514.6-179.3-65.6-79.4000113.7I61 P62 L68 I72 A73 F74 F81 F95 T96I61-H70 PolarHBondContact O-NE2 2.93Å; I61-H70 VanDerWaalsContact O-NE2 3.16Å; P62-H70 PolarHBondContact O-CE1 3.25Å; P62-H70 PolarHBondContact O-NE2 2.89Å; P62-H70 VanDerWaalsContact O-NE2 3.08Å; L68-H70 PolarHBondContact O-N 3.43Å; H70-I72 VanDerWaalsContact C-N 3.28Å; H70-I72 PolarHBondContact O-N 3.39Å; H70-I72 VanDerWaalsContact O-N 3.16Å; H70-A73 PolarHBondContact O-N 3.45Å; H70-F74 VanDerWaalsContact O-CB 3.32Å; H70-F74 WeakPolarHBondContact O-CB 3.24Å; H70-F74 PolarHBondContact O-N 3.44Å; H70-F81 HydrophobicContact CB-CE2 3.79Å; H70-F81 HydrophobicContact CB-CZ 3.77Å; H70-F81 AromaticContact CG-CE2 3.83Å; H70-F81 AromaticContact CG-CZ 3.79Å; H70-F81 AromaticContact ND1-CE2 3.74Å; H70-F95 HydrophobicContact CB-CD2 4.08Å; H70-T96 PolarHBondContact N-O 3.48Å
71A90.5Very high92.7Very high22 Ų2261.4 Ų61.418%0.18235%0.351CS..Hα-helixtrans-55.9-37.2-172.500000114.1L68 G75 M97 V98L68-A71 HydrophobicContact CD1-CB 3.65Å; L68-A71 HydrophobicContact CG-CB 4.05Å; L68-A71 WeakPolarHBondContact O-CB 3.37Å; L68-A71 PolarHBondContact O-N 2.94Å; A71-G75 PolarHBondContact O-N 3.09Å; A71-M97 HydrophobicContact CB-CB 4.21Å; A71-M97 HydrophobicContact CB-CG 4.4Å; A71-V98 HydrophobicContact CB-CG2 3.82Å
72I90.6Very high92.7Very high114 Ų11460.8 Ų60.859%0.58535%0.348SS*.Hα-helixtrans-70.5-49.5177.9-61.1173.8000111L68 H70 F74 G75 K76L68-I72 HydrophobicContact CD2-CD1 3.73Å; L68-I72 HydrophobicContact CD2-CG1 3.95Å; H70-I72 VanDerWaalsContact C-N 3.28Å; H70-I72 PolarHBondContact O-N 3.39Å; H70-I72 VanDerWaalsContact O-N 3.16Å; I72-F74 VanDerWaalsContact C-N 3.35Å; I72-F74 PolarHBondContact O-N 3.33Å; I72-G75 PolarHBondContact O-N 3.34Å; I72-K76 WeakPolarHBondContact O-CB 3.07Å; I72-K76 PolarHBondContact O-N 2.99Å
73A93.3Very high92.8Very high49 Ų4957.8 Ų57.841%0.40533%0.326SS..Hα-helixtrans-62.1-45.5-17900000111H70 K76 S77 F81H70-A73 PolarHBondContact O-N 3.45Å; A73-K76 PolarHBondContact O-N 3.4Å; A73-S77 PolarHBondContact O-N 3.46Å; A73-F81 HydrophobicContact CB-CD2 4.1Å; A73-F81 HydrophobicContact CB-CE2 4.36Å
74F93.1Very high92.9Very high24 Ų2459.8 Ų59.811%0.10533%0.333CS..Hα-helixtrans-64.3-45.3175.6-173.7-90.3000112H70 I72 K76 P78 F81 L82 F95 M97 Y104 M375H70-F74 VanDerWaalsContact O-CB 3.32Å; H70-F74 WeakPolarHBondContact O-CB 3.24Å; H70-F74 PolarHBondContact O-N 3.44Å; I72-F74 VanDerWaalsContact C-N 3.35Å; I72-F74 PolarHBondContact O-N 3.33Å; F74-K76 VanDerWaalsContact C-N 3.31Å; F74-K76 PolarHBondContact O-N 2.86Å; F74-P78 HydrophobicContact CD1-CB 4.28Å; F74-P78 HydrophobicContact CD2-CB 4.31Å; F74-P78 HydrophobicContact CE1-CB 3.97Å; F74-P78 HydrophobicContact CE2-CB 4Å; F74-P78 HydrophobicContact CG-CB 4.43Å; F74-P78 HydrophobicContact CZ-CB 3.8Å; F74-P78 WeakPolarHBondContact O-CA 3.36Å; F74-P78 WeakPolarHBondContact O-CB 3.38Å; F74-P78 WeakPolarHBondContact O-CD 3.38Å; F74-F81 AromaticContact CD2-CD1 3.76Å; F74-F81 HydrophobicContact CD2-CD1 3.76Å; F74-F81 HydrophobicContact CD2-CE1 4.27Å; F74-F81 HydrophobicContact CD2-CG 4.29Å; F74-L82 HydrophobicContact CE2-CD1 4.08Å; F74-L82 HydrophobicContact CE2-CD2 4.12Å; F74-L82 HydrophobicContact CE2-CG 3.99Å; F74-F95 HydrophobicContact CD2-CE2 4.06Å; F74-F95 AromaticContact CD2-CZ 3.79Å; F74-F95 HydrophobicContact CD2-CZ 3.79Å; F74-F95 HydrophobicContact CE2-CZ 4.03Å; F74-F95 HydrophobicContact CG-CE2 4.42Å; F74-M97 HydrophobicContact CB-SD 3.61Å; F74-M97 HydrophobicContact CD1-CE 4Å; F74-M97 HydrophobicContact CD1-SD 3.47Å; F74-M97 WeakPolarHBondContact CD1-SD 3.15Å; F74-M97 HydrophobicContact CD2-SD 4.26Å; F74-M97 HydrophobicContact CE1-CE 4.19Å; F74-M97 HydrophobicContact CE1-SD 4.24Å; F74-M97 HydrophobicContact CG-CE 4.23Å; F74-M97 HydrophobicContact CG-SD 3.49Å; F74-M97 WeakPolarHBondContact CG-SD 3.37Å; F74-Y104 HydrophobicContact CE2-CE2 4.39Å; F74-Y104 WeakPolarHBondContact CZ-OH 3.4Å; F74-M375 HydrophobicContact CE1-CE 4.33Å; F74-M375 HydrophobicContact CZ-CE 4.4Å
75G88.3Confident93.2Very high37 Ų3754.4 Ų54.438%0.38130%0.296SS..Hα-helixtrans-65.9-30.9179.400000113.9A71 I72A71-G75 PolarHBondContact O-N 3.09Å; I72-G75 PolarHBondContact O-N 3.34Å
76K89.9Confident93.5Very high170 Ų17053 Ų5374%0.73929%0.286SS*.Hα-helixtrans-75.8-43.7-180-173.3178.5179.4-176.30113I72 A73 F74 Y478I72-K76 WeakPolarHBondContact O-CB 3.07Å; I72-K76 PolarHBondContact O-N 2.99Å; A73-K76 PolarHBondContact O-N 3.4Å; F74-K76 VanDerWaalsContact C-N 3.31Å; F74-K76 PolarHBondContact O-N 2.86Å; K76-Y478 WeakPolarHBondContact O-CD2 3.49Å
77S91.8Very high94Very high29 Ų2953 Ų5320%0.20328%0.275CS..  trans-148.774-177.4-164.70000109.7A73 I79 E80 F81A73-S77 PolarHBondContact O-N 3.46Å; S77-I79 VanDerWaalsContact C-N 3.28Å; S77-I79 PolarHBondContact O-N 2.95Å; S77-E80 WeakPolarHBondContact CB-OE2 3.15Å; S77-E80 PolarHBondContact O-N 3.35Å; S77-E80 WeakPolarHBondContact OG-CB 3.36Å; S77-E80 PolarHBondContact OG-OE2 2.98Å; S77-F81 WeakPolarHBondContact O-CB 3.3Å; S77-F81 PolarHBondContact O-N 3.07Å
78P94.9Very high94.4Very high2 Ų253.7 Ų53.71%0.01328%0.278CS..Hα-helixtrans-63.9-36-170.119.4-28.7000112.2F74 L82 M375 Y478F74-P78 HydrophobicContact CD1-CB 4.28Å; F74-P78 HydrophobicContact CD2-CB 4.31Å; F74-P78 HydrophobicContact CE1-CB 3.97Å; F74-P78 HydrophobicContact CE2-CB 4Å; F74-P78 HydrophobicContact CG-CB 4.43Å; F74-P78 HydrophobicContact CZ-CB 3.8Å; F74-P78 WeakPolarHBondContact O-CA 3.36Å; F74-P78 WeakPolarHBondContact O-CB 3.38Å; F74-P78 WeakPolarHBondContact O-CD 3.38Å; P78-L82 WeakPolarHBondContact O-CB 3.45Å; P78-L82 WeakPolarHBondContact O-CG 3.28Å; P78-L82 PolarHBondContact O-N 3.47Å; P78-L82 VanDerWaalsContact O-N 3.07Å; P78-M375 HydrophobicContact CB-CE 3.52Å; P78-M375 HydrophobicContact CB-SD 4.19Å; P78-M375 HydrophobicContact CG-CE 3.44Å; P78-M375 VanDerWaalsContact CG-CE 3.44Å; P78-M375 HydrophobicContact CG-SD 4.35Å; P78-Y478 HydrophobicContact CG-CD1 3.64Å; P78-Y478 HydrophobicContact CG-CE1 3.94Å; P78-Y478 HydrophobicContact CG-CG 4.12Å
79I95.4Very high94.8Very high5 Ų553.7 Ų53.73%0.02628%0.275CS..Hα-helixtrans-69.7-49.9-178.7-53.6-53.1000110.7S77 F81 L82 E83 T403 V404 Y478S77-I79 VanDerWaalsContact C-N 3.28Å; S77-I79 PolarHBondContact O-N 2.95Å; I79-F81 VanDerWaalsContact C-N 3.28Å; I79-F81 PolarHBondContact O-N 2.88Å; I79-L82 PolarHBondContact O-N 3.38Å; I79-L82 VanDerWaalsContact O-N 3.14Å; I79-E83 HydrophobicContact CG2-CG 4.37Å; I79-E83 WeakPolarHBondContact O-CG 3.43Å; I79-E83 PolarHBondContact O-N 3.19Å; I79-T403 HydrophobicContact CD1-CG2 3.88Å; I79-T403 HydrophobicContact CG1-CG2 4.48Å; I79-V404 HydrophobicContact CD1-CG2 4.5Å; I79-Y478 HydrophobicContact CG1-CE1 4.24Å
80E96.4Very high95Very high112 Ų11254.4 Ų54.452%0.52328%0.282SS..Hα-helixtrans-61.7-40.4179.1-172.7-174172.800110.9S77 L82 E83 N84S77-E80 WeakPolarHBondContact CB-OE2 3.15Å; S77-E80 PolarHBondContact O-N 3.35Å; S77-E80 WeakPolarHBondContact OG-CB 3.36Å; S77-E80 PolarHBondContact OG-OE2 2.98Å; E80-L82 VanDerWaalsContact C-N 3.33Å; E80-L82 PolarHBondContact O-N 3.33Å; E80-E83 PolarHBondContact O-N 3.15Å; E80-N84 VanDerWaalsContact O-CB 3.3Å; E80-N84 WeakPolarHBondContact O-CB 3.4Å; E80-N84 PolarHBondContact O-N 3.35Å; E80-N84 PolarHBondContact O-ND2 3.15Å
81F97.6Very high95.1Very high30 Ų3055.3 Ų55.313%0.13229%0.291CS..Hα-helixtrans-56.6-47.1173.2-178.8-85.7000111.7I61 H70 A73 F74 S77 I79 A85 F95I61-F81 HydrophobicContact CD1-CE1 4.3Å; I61-F81 HydrophobicContact CD1-CZ 4.17Å; H70-F81 HydrophobicContact CB-CE2 3.79Å; H70-F81 HydrophobicContact CB-CZ 3.77Å; H70-F81 AromaticContact CG-CE2 3.83Å; H70-F81 AromaticContact CG-CZ 3.79Å; H70-F81 AromaticContact ND1-CE2 3.74Å; A73-F81 HydrophobicContact CB-CD2 4.1Å; A73-F81 HydrophobicContact CB-CE2 4.36Å; F74-F81 AromaticContact CD2-CD1 3.76Å; F74-F81 HydrophobicContact CD2-CD1 3.76Å; F74-F81 HydrophobicContact CD2-CE1 4.27Å; F74-F81 HydrophobicContact CD2-CG 4.29Å; S77-F81 WeakPolarHBondContact O-CB 3.3Å; S77-F81 PolarHBondContact O-N 3.07Å; I79-F81 VanDerWaalsContact C-N 3.28Å; I79-F81 PolarHBondContact O-N 2.88Å; F81-A85 VanDerWaalsContact O-CB 3.25Å; F81-A85 WeakPolarHBondContact O-CB 3.17Å; F81-A85 PolarHBondContact O-N 3.08Å; F81-F95 HydrophobicContact CD1-CZ 4.38Å; F81-F95 HydrophobicContact CE1-CD1 4.03Å; F81-F95 HydrophobicContact CE1-CD2 4.08Å; F81-F95 AromaticContact CE1-CE1 3.81Å; F81-F95 HydrophobicContact CE1-CE1 3.81Å; F81-F95 AromaticContact CE1-CE2 3.83Å; F81-F95 HydrophobicContact CE1-CE2 3.83Å; F81-F95 HydrophobicContact CE1-CG 4.16Å; F81-F95 AromaticContact CE1-CZ 3.71Å; F81-F95 HydrophobicContact CE1-CZ 3.71Å; F81-F95 HydrophobicContact CZ-CD2 4.11Å; F81-F95 HydrophobicContact CZ-CE2 4.23Å; F81-F95 HydrophobicContact CZ-CG 4.25Å
82L98.1Very high95.5Very high0 Ų054.3 Ų54.30%028%0.282CS..Hα-helixtrans-71.2-38.5-179.1-69.6173.9000112.9F74 P78 I79 E80 A85 Y86 F93 F95 Y104 L106 V404F74-L82 HydrophobicContact CE2-CD1 4.08Å; F74-L82 HydrophobicContact CE2-CD2 4.12Å; F74-L82 HydrophobicContact CE2-CG 3.99Å; P78-L82 WeakPolarHBondContact O-CB 3.45Å; P78-L82 WeakPolarHBondContact O-CG 3.28Å; P78-L82 PolarHBondContact O-N 3.47Å; P78-L82 VanDerWaalsContact O-N 3.07Å; I79-L82 PolarHBondContact O-N 3.38Å; I79-L82 VanDerWaalsContact O-N 3.14Å; E80-L82 VanDerWaalsContact C-N 3.33Å; E80-L82 PolarHBondContact O-N 3.33Å; L82-A85 PolarHBondContact O-N 2.89Å; L82-Y86 WeakPolarHBondContact O-CB 3.34Å; L82-Y86 PolarHBondContact O-N 3.4Å; L82-F93 HydrophobicContact CD2-CE2 4Å; L82-F93 HydrophobicContact CD2-CZ 3.84Å; L82-F95 HydrophobicContact CD2-CE1 4.36Å; L82-Y104 HydrophobicContact CD1-CD1 3.98Å; L82-Y104 HydrophobicContact CD1-CE1 3.53Å; L82-Y104 HydrophobicContact CD2-CD1 3.57Å; L82-Y104 HydrophobicContact CD2-CD2 3.93Å; L82-Y104 HydrophobicContact CD2-CE1 3.71Å; L82-Y104 HydrophobicContact CD2-CE2 4.05Å; L82-Y104 HydrophobicContact CD2-CG 3.67Å; L82-Y104 HydrophobicContact CG-CD1 4.44Å; L82-Y104 HydrophobicContact CG-CE1 4.28Å; L82-L106 HydrophobicContact CB-CD1 4.32Å; L82-V404 HydrophobicContact CB-CG2 3.82Å; L82-V404 HydrophobicContact CD1-CG2 3.93Å
83E97.3Very high95.9Very high28 Ų2848.9 Ų48.913%0.13125%0.254CS..Hα-helixtrans-64.3-45.9175.1-72.6-172.4174.400110.9I79 E80 A85 Y86 E87 V404 R407 R415I79-E83 HydrophobicContact CG2-CG 4.37Å; I79-E83 WeakPolarHBondContact O-CG 3.43Å; I79-E83 PolarHBondContact O-N 3.19Å; E80-E83 PolarHBondContact O-N 3.15Å; E83-A85 VanDerWaalsContact C-N 3.32Å; E83-A85 PolarHBondContact O-N 3.48Å; E83-Y86 WeakPolarHBondContact O-CB 3.47Å; E83-Y86 PolarHBondContact O-N 2.87Å; E83-E87 WeakPolarHBondContact O-CG 3.09Å; E83-E87 PolarHBondContact O-N 2.98Å; E83-V404 HydrophobicContact CG-CG1 4.48Å; E83-R407 WeakPolarHBondContact OE1-CD 3.29Å; E83-R407 IonicContact OE1-NE 3.52Å; E83-R415 IonicContact OE1-CZ 3.01Å; E83-R415 IonicContact OE1-NH1 3.73Å; E83-R415 PolarHBondContact OE1-NH1 2.8Å; E83-R415 IonicContact OE1-NH2 3Å; E83-R415 IonicContact OE2-CZ 2.73Å; E83-R415 IonicContact OE2-NH1 2.73Å; E83-R415 PolarHBondContact OE2-NH1 2.84Å; E83-R415 IonicContact OE2-NH2 3.6Å; E83-R415 PolarHBondContact OE2-NH2 2.85Å
84N97.8Very high96.1Very high87 Ų8746.6 Ų46.647%0.46524%0.236SC..Hα-helixtrans-63.6-38.6176.1-69.8-21.3000112E80 K88E80-N84 VanDerWaalsContact O-CB 3.3Å; E80-N84 WeakPolarHBondContact O-CB 3.4Å; E80-N84 PolarHBondContact O-N 3.35Å; E80-N84 PolarHBondContact O-ND2 3.15Å; N84-K88 WeakPolarHBondContact O-CB 3.42Å; N84-K88 PolarHBondContact O-N 3.32Å
85A98.1Very high96.4Very high5 Ų545.5 Ų45.54%0.04123%0.231CC..Hα-helixtrans-66.8-39.4175.100000111.8I61 F81 L82 E83 K88 Y89 F93I61-A85 HydrophobicContact CD1-CB 3.7Å; F81-A85 VanDerWaalsContact O-CB 3.25Å; F81-A85 WeakPolarHBondContact O-CB 3.17Å; F81-A85 PolarHBondContact O-N 3.08Å; L82-A85 PolarHBondContact O-N 2.89Å; E83-A85 VanDerWaalsContact C-N 3.32Å; E83-A85 PolarHBondContact O-N 3.48Å; A85-K88 PolarHBondContact O-N 2.75Å; A85-Y89 HydrophobicContact CB-CD2 4.44Å; A85-Y89 WeakPolarHBondContact O-CA 3.48Å; A85-Y89 WeakPolarHBondContact O-CB 3.41Å; A85-Y89 WeakPolarHBondContact O-CD2 3.33Å; A85-Y89 PolarHBondContact O-N 3.44Å; A85-F93 HydrophobicContact CB-CD1 4.28Å; A85-F93 HydrophobicContact CB-CD2 4.1Å; A85-F93 HydrophobicContact CB-CE1 3.75Å; A85-F93 HydrophobicContact CB-CE2 3.55Å; A85-F93 HydrophobicContact CB-CG 4.43Å; A85-F93 HydrophobicContact CB-CZ 3.36Å
86Y97.6Very high96.7Very high52 Ų5244.7 Ų44.720%0.20422%0.218CC..Hα-helixtrans-61.1-48.3174.8179.6-95.6000111.8L82 E83 K88 G90 P91 L106 L408 D410L82-Y86 WeakPolarHBondContact O-CB 3.34Å; L82-Y86 PolarHBondContact O-N 3.4Å; E83-Y86 WeakPolarHBondContact O-CB 3.47Å; E83-Y86 PolarHBondContact O-N 2.87Å; Y86-K88 PolarHBondContact O-N 3.36Å; Y86-G90 WeakPolarHBondContact O-CA 3.25Å; Y86-G90 PolarHBondContact O-N 2.84Å; Y86-P91 HydrophobicContact CE2-CB 4.02Å; Y86-L106 HydrophobicContact CD2-CB 3.78Å; Y86-L106 HydrophobicContact CD2-CD1 4.13Å; Y86-L106 HydrophobicContact CE2-CB 4.25Å; Y86-L106 HydrophobicContact CG-CD1 4.43Å; Y86-L408 HydrophobicContact CD1-CD2 3.88Å; Y86-L408 HydrophobicContact CD2-CD2 4.24Å; Y86-L408 HydrophobicContact CE1-CD2 3.74Å; Y86-L408 HydrophobicContact CE2-CD2 4.08Å; Y86-L408 HydrophobicContact CG-CD2 4.13Å; Y86-D410 PolarHBondContact OH-OD2 2.81Å; Y86-D410 VanDerWaalsContact OH-OD2 3.05Å
87E96.4Very high96.9Very high115 Ų11537.2 Ų37.254%0.53719%0.186SC..Hα-helixtrans-61.5-33.2179.5-71.4-179.7-178.900112.3E83 R409E83-E87 WeakPolarHBondContact O-CG 3.09Å; E83-E87 PolarHBondContact O-N 2.98Å; E87-R409 IonicContact OE1-CZ 3.05Å; E87-R409 IonicContact OE1-NE 2.79Å; E87-R409 PolarHBondContact OE1-NE 2.8Å; E87-R409 IonicContact OE1-NH2 3.23Å
88K97.7Very high96.8Very high155 Ų15537.2 Ų37.267%0.67419%0.185SC*.Hα-helixtrans-91.6-37.4-176.9-174.6172178.8-174.30114.8N84 A85 Y86N84-K88 WeakPolarHBondContact O-CB 3.42Å; N84-K88 PolarHBondContact O-N 3.32Å; A85-K88 PolarHBondContact O-N 2.75Å; Y86-K88 PolarHBondContact O-N 3.36Å
89Y97.6Very high96.5Very high55 Ų5538.3 Ų38.322%0.21620%0.197CC..Hα-helixtrans-116.8-5.8-170.1-59.7-78000113.2P59 I61 A85P59-Y89 HydrophobicContact CB-CD1 3.82Å; P59-Y89 HydrophobicContact CB-CG 4.48Å; P59-Y89 HydrophobicContact CG-CD1 4.4Å; I61-Y89 HydrophobicContact CB-CE2 4.44Å; I61-Y89 HydrophobicContact CD1-CD2 4.12Å; I61-Y89 HydrophobicContact CD1-CE2 4.12Å; I61-Y89 HydrophobicContact CG1-CD2 3.93Å; I61-Y89 HydrophobicContact CG1-CE2 3.75Å; I61-Y89 HydrophobicContact CG2-CE2 4.18Å; A85-Y89 HydrophobicContact CB-CD2 4.44Å; A85-Y89 WeakPolarHBondContact O-CA 3.48Å; A85-Y89 WeakPolarHBondContact O-CB 3.41Å; A85-Y89 WeakPolarHBondContact O-CD2 3.33Å; A85-Y89 PolarHBondContact O-N 3.44Å
90G97.2Very high96.3Very high22 Ų2243.3 Ų43.323%0.22722%0.218CC..  trans82.2-162.1179.800000113.7Y86 V92 F93Y86-G90 WeakPolarHBondContact O-CA 3.25Å; Y86-G90 PolarHBondContact O-N 2.84Å; G90-V92 VanDerWaalsContact C-N 3.32Å; G90-V92 PolarHBondContact O-N 3.03Å; G90-F93 WeakPolarHBondContact O-CD1 3.28Å
91P97.5Very high96.4Very high49 Ų4939.5 Ų39.532%0.31820%0.203SC..SBendtrans-75.2-14.6-168.829.5-36.6000114.9Y86 L106 A110Y86-P91 HydrophobicContact CE2-CB 4.02Å; P91-L106 WeakPolarHBondContact CB-O 3.43Å; P91-L106 PolarHBondContact O-N 3.13Å; P91-A110 HydrophobicContact CB-CB 4.06Å
92V98.6Very high96.4Very high0 Ų038.2 Ų38.20%020%0.197CC..EExtended strand (participates in β ladder)trans-133.5117.2-178.3-175.70000109.4P58 P59 G90 T103 Y104 L105 A110 A387 A388 Y390P58-V92 HydrophobicContact CB-CG1 4.07Å; P58-V92 HydrophobicContact CG-CG1 4.01Å; P59-V92 VanDerWaalsContact CD-O 3.27Å; P59-V92 WeakPolarHBondContact CD-O 3.32Å; P59-V92 WeakPolarHBondContact CG-O 3.2Å; G90-V92 VanDerWaalsContact C-N 3.32Å; G90-V92 PolarHBondContact O-N 3.03Å; V92-T103 HydrophobicContact CG1-CG2 4.14Å; V92-Y104 WeakPolarHBondContact CA-O 3.08Å; V92-L105 HydrophobicContact CB-CD2 4.49Å; V92-L105 HydrophobicContact CG1-CD2 3.96Å; V92-L105 HydrophobicContact CG2-CD2 3.89Å; V92-A110 HydrophobicContact CG2-CB 3.86Å; V92-A387 HydrophobicContact CG2-CB 4.23Å; V92-A388 HydrophobicContact CB-CB 4.49Å; V92-A388 HydrophobicContact CG2-CB 3.69Å; V92-Y390 HydrophobicContact CB-CD2 3.99Å; V92-Y390 HydrophobicContact CB-CE2 4.41Å; V92-Y390 HydrophobicContact CG1-CD2 4.17Å
93F98.7Very high96.4Very high0 Ų038.2 Ų38.20%020%0.197CC..EExtended strand (participates in β ladder)trans-150.7159.4178.655.8-97.6000111.5P59 I61 L82 A85 G90 F95 T103 Y104 L106P59-F93 HydrophobicContact CG-CB 4.11Å; P59-F93 WeakPolarHBondContact O-CA 3.44Å; I61-F93 HydrophobicContact CD1-CD2 3.73Å; I61-F93 HydrophobicContact CD1-CE2 4.12Å; I61-F93 HydrophobicContact CD1-CG 4.44Å; I61-F93 HydrophobicContact CG1-CD2 4.42Å; L82-F93 HydrophobicContact CD2-CE2 4Å; L82-F93 HydrophobicContact CD2-CZ 3.84Å; A85-F93 HydrophobicContact CB-CD1 4.28Å; A85-F93 HydrophobicContact CB-CD2 4.1Å; A85-F93 HydrophobicContact CB-CE1 3.75Å; A85-F93 HydrophobicContact CB-CE2 3.55Å; A85-F93 HydrophobicContact CB-CG 4.43Å; A85-F93 HydrophobicContact CB-CZ 3.36Å; G90-F93 WeakPolarHBondContact O-CD1 3.28Å; F93-F95 HydrophobicContact CD2-CD1 4.07Å; F93-F95 HydrophobicContact CD2-CE1 4.41Å; F93-F95 HydrophobicContact CE2-CD1 4.04Å; F93-F95 AromaticContact CE2-CE1 3.95Å; F93-F95 HydrophobicContact CE2-CE1 3.95Å; F93-T103 CarbonylContact O-C 3.58Å; F93-T103 VanDerWaalsContact O-CA 3.3Å; F93-T103 WeakPolarHBondContact O-CA 3.33Å; F93-Y104 HydrophobicContact CE2-CG 4.43Å; F93-Y104 PolarHBondContact N-O 2.85Å; F93-Y104 PolarHBondContact O-N 3.3Å; F93-L106 HydrophobicContact CE1-CD1 3.62Å; F93-L106 HydrophobicContact CE1-CG 4.3Å; F93-L106 HydrophobicContact CZ-CD1 3.72Å; F93-L106 HydrophobicContact CZ-CG 4.47Å
94S98.7Very high96.5Very high2 Ų237 Ų371%0.01419%0.191CC..EExtended strand (participates in β ladder)trans-121.7149.6179.9-58.90000112.7P59 Y60 I61 F102 T103P59-S94 PolarHBondContact O-N 3.31Å; Y60-S94 CarbonylContact C-O 3.46Å; Y60-S94 VanDerWaalsContact CA-O 3.31Å; Y60-S94 WeakPolarHBondContact CA-O 3.5Å; I61-S94 PolarHBondContact N-O 2.9Å; S94-F102 CarbonylContact C-O 3.39Å; S94-F102 WeakPolarHBondContact CA-O 3.42Å; S94-F102 WeakPolarHBondContact CB-O 3.48Å; S94-T103 PolarHBondContact OG-OG1 3.47Å
95F98Very high96.5Very high0 Ų032.9 Ų32.90%017%0.169CC..EExtended strand (participates in β ladder)trans-155.6161.9172.564.3-86000110.9I61 H70 F74 F81 L82 F93 M97 F102 Y104I61-F95 HydrophobicContact CB-CB 3.96Å; I61-F95 HydrophobicContact CD1-CB 4.23Å; I61-F95 HydrophobicContact CD1-CD1 4.28Å; I61-F95 HydrophobicContact CG1-CB 4.24Å; H70-F95 HydrophobicContact CB-CD2 4.08Å; F74-F95 HydrophobicContact CD2-CE2 4.06Å; F74-F95 AromaticContact CD2-CZ 3.79Å; F74-F95 HydrophobicContact CD2-CZ 3.79Å; F74-F95 HydrophobicContact CE2-CZ 4.03Å; F74-F95 HydrophobicContact CG-CE2 4.42Å; F81-F95 HydrophobicContact CD1-CZ 4.38Å; F81-F95 HydrophobicContact CE1-CD1 4.03Å; F81-F95 HydrophobicContact CE1-CD2 4.08Å; F81-F95 AromaticContact CE1-CE1 3.81Å; F81-F95 HydrophobicContact CE1-CE1 3.81Å; F81-F95 AromaticContact CE1-CE2 3.83Å; F81-F95 HydrophobicContact CE1-CE2 3.83Å; F81-F95 HydrophobicContact CE1-CG 4.16Å; F81-F95 AromaticContact CE1-CZ 3.71Å; F81-F95 HydrophobicContact CE1-CZ 3.71Å; F81-F95 HydrophobicContact CZ-CD2 4.11Å; F81-F95 HydrophobicContact CZ-CE2 4.23Å; F81-F95 HydrophobicContact CZ-CG 4.25Å; L82-F95 HydrophobicContact CD2-CE1 4.36Å; F93-F95 HydrophobicContact CD2-CD1 4.07Å; F93-F95 HydrophobicContact CD2-CE1 4.41Å; F93-F95 HydrophobicContact CE2-CD1 4.04Å; F93-F95 AromaticContact CE2-CE1 3.95Å; F93-F95 HydrophobicContact CE2-CE1 3.95Å; F95-M97 HydrophobicContact CD2-CG 3.88Å; F95-M97 HydrophobicContact CD2-SD 4.5Å; F95-M97 HydrophobicContact CE2-CE 3.61Å; F95-M97 HydrophobicContact CE2-CG 3.59Å; F95-M97 HydrophobicContact CE2-SD 3.63Å; F95-M97 HydrophobicContact CZ-CE 4Å; F95-M97 HydrophobicContact CZ-SD 4.44Å; F95-F102 HydrophobicContact CE1-CB 4.38Å; F95-F102 HydrophobicContact CZ-CB 4.37Å; F95-F102 PolarHBondContact N-O 3.41Å; F95-F102 PolarHBondContact O-N 2.91Å; F95-Y104 HydrophobicContact CD1-CD2 4.5Å; F95-Y104 AromaticContact CE1-CD2 3.45Å; F95-Y104 HydrophobicContact CE1-CD2 3.45Å; F95-Y104 VanDerWaalsContact CE1-CD2 3.45Å; F95-Y104 AromaticContact CE1-CE2 3.67Å; F95-Y104 HydrophobicContact CE1-CE2 3.67Å; F95-Y104 HydrophobicContact CE1-CG 4.46Å; F95-Y104 AromaticContact CZ-CD2 3.94Å; F95-Y104 HydrophobicContact CZ-CD2 3.94Å; F95-Y104 AromaticContact CZ-CE2 3.63Å; F95-Y104 HydrophobicContact CZ-CE2 3.63Å
96T96.3Very high96.5Very high20 Ų2032.7 Ų32.712%0.12317%0.168CC..EExtended strand (participates in β ladder)trans-97.4139.2178-730000112.2Y60 G69 H70 K100Y60-T96 WeakPolarHBondContact OH-CB 3.45Å; Y60-T96 PolarHBondContact OH-OG1 2.85Å; G69-T96 CarbonylContact C-O 3.26Å; G69-T96 WeakPolarHBondContact CA-O 3.42Å; H70-T96 PolarHBondContact N-O 3.48Å; T96-K100 VanDerWaalsContact CA-O 3.24Å; T96-K100 WeakPolarHBondContact CA-O 3.18Å
97M92.7Very high96.4Very high14 Ų1430.7 Ų30.77%0.06916%0.163CC..EExtended strand (participates in β ladder)trans-134.8129.2162.2-62-174.4-74.600109.1L68 A71 F74 F95 G99 K100 F102L68-M97 WeakPolarHBondContact O-CA 3.47Å; A71-M97 HydrophobicContact CB-CB 4.21Å; A71-M97 HydrophobicContact CB-CG 4.4Å; F74-M97 HydrophobicContact CB-SD 3.61Å; F74-M97 HydrophobicContact CD1-CE 4Å; F74-M97 HydrophobicContact CD1-SD 3.47Å; F74-M97 WeakPolarHBondContact CD1-SD 3.15Å; F74-M97 HydrophobicContact CD2-SD 4.26Å; F74-M97 HydrophobicContact CE1-CE 4.19Å; F74-M97 HydrophobicContact CE1-SD 4.24Å; F74-M97 HydrophobicContact CG-CE 4.23Å; F74-M97 HydrophobicContact CG-SD 3.49Å; F74-M97 WeakPolarHBondContact CG-SD 3.37Å; F95-M97 HydrophobicContact CD2-CG 3.88Å; F95-M97 HydrophobicContact CD2-SD 4.5Å; F95-M97 HydrophobicContact CE2-CE 3.61Å; F95-M97 HydrophobicContact CE2-CG 3.59Å; F95-M97 HydrophobicContact CE2-SD 3.63Å; F95-M97 HydrophobicContact CZ-CE 4Å; F95-M97 HydrophobicContact CZ-SD 4.44Å; M97-G99 VanDerWaalsContact C-N 3.28Å; M97-G99 PolarHBondContact O-N 2.66Å; M97-G99 VanDerWaalsContact O-N 3.16Å; M97-K100 PolarHBondContact N-O 3.48Å; M97-K100 PolarHBondContact O-N 2.93Å; M97-F102 HydrophobicContact CB-CD2 4.03Å; M97-F102 HydrophobicContact CB-CE2 3.7Å; M97-F102 HydrophobicContact CE-CD1 3.89Å; M97-F102 HydrophobicContact CE-CD2 3.6Å; M97-F102 HydrophobicContact CE-CE1 3.96Å; M97-F102 HydrophobicContact CE-CE2 3.7Å; M97-F102 HydrophobicContact CE-CG 3.71Å; M97-F102 HydrophobicContact CE-CZ 3.87Å; M97-F102 HydrophobicContact CG-CD2 4.31Å; M97-F102 HydrophobicContact CG-CE2 4.4Å
98V89.5Confident96.3Very high28 Ų2826 Ų2617%0.1714%0.143CC..THydrogen-bonded Turntrans4649.7174.2-155.90000113.4F67 L68 A71 K100 W236 L237F67-V98 HydrophobicContact CE1-CG1 3.63Å; F67-V98 HydrophobicContact CZ-CG1 3.64Å; F67-V98 CarbonylContact O-C 3.55Å; F67-V98 WeakPolarHBondContact O-CA 3.36Å; F67-V98 PolarHBondContact O-N 3.32Å; F67-V98 VanDerWaalsContact O-N 3.15Å; L68-V98 HydrophobicContact CD1-CG2 4.38Å; L68-V98 PolarHBondContact O-N 3.45Å; A71-V98 HydrophobicContact CB-CG2 3.82Å; V98-K100 VanDerWaalsContact C-N 3.27Å; V98-K100 PolarHBondContact O-N 3.47Å; V98-W236 HydrophobicContact CG2-CZ3 4.42Å; V98-L237 HydrophobicContact CB-CD2 3.64Å; V98-L237 HydrophobicContact CG1-CD1 4.08Å; V98-L237 HydrophobicContact CG1-CD2 3.41Å; V98-L237 VanDerWaalsContact CG1-CD2 3.41Å; V98-L237 HydrophobicContact CG1-CG 4.32Å; V98-L237 HydrophobicContact CG2-CD1 4.22Å; V98-L237 HydrophobicContact CG2-CD2 3.94Å
99G88.6Confident96.2Very high26 Ų2625.5 Ų25.527%0.26815%0.148SC..THydrogen-bonded Turntrans78-0.3175.300000115.8F67 M97F67-G99 PolarHBondContact O-N 2.99Å; M97-G99 VanDerWaalsContact C-N 3.28Å; M97-G99 PolarHBondContact O-N 2.66Å; M97-G99 VanDerWaalsContact O-N 3.16Å
100K92.2Very high96.1Very high109 Ų10923.2 Ų23.247%0.47414%0.14SC..EExtended strand (participates in β ladder)trans-109.7147.5176.9-62.2-66.9-176.9175.70111.1T96 M97 V98 F102T96-K100 VanDerWaalsContact CA-O 3.24Å; T96-K100 WeakPolarHBondContact CA-O 3.18Å; M97-K100 PolarHBondContact N-O 3.48Å; M97-K100 PolarHBondContact O-N 2.93Å; V98-K100 VanDerWaalsContact C-N 3.27Å; V98-K100 PolarHBondContact O-N 3.47Å; K100-F102 HydrophobicContact CB-CE2 3.76Å; K100-F102 HydrophobicContact CB-CZ 4.26Å
101T97.4Very high96.1Very high32 Ų3222.1 Ų22.120%0.19613%0.129CC..EExtended strand (participates in β ladder)trans-96.9124.1174.3-55.10000109.6Y60 H396 Q397Y60-T101 HydrophobicContact CE2-CG2 4.16Å; T101-H396 VanDerWaalsContact CG2-CE1 3.4Å; T101-H396 WeakPolarHBondContact CG2-CE1 3.44Å; T101-H396 WeakPolarHBondContact CG2-NE2 3.49Å; T101-Q397 PolarHBondContact O-N 3.23Å
102F98.1Very high96Very high3 Ų321.9 Ų21.91%0.01313%0.126CC..EExtended strand (participates in β ladder)trans-102.2140.4175.5-66.4-97.1000108.6S94 F95 M97 K100 Y104 W236 M378 Q397S94-F102 CarbonylContact C-O 3.39Å; S94-F102 WeakPolarHBondContact CA-O 3.42Å; S94-F102 WeakPolarHBondContact CB-O 3.48Å; F95-F102 HydrophobicContact CE1-CB 4.38Å; F95-F102 HydrophobicContact CZ-CB 4.37Å; F95-F102 PolarHBondContact N-O 3.41Å; F95-F102 PolarHBondContact O-N 2.91Å; M97-F102 HydrophobicContact CB-CD2 4.03Å; M97-F102 HydrophobicContact CB-CE2 3.7Å; M97-F102 HydrophobicContact CE-CD1 3.89Å; M97-F102 HydrophobicContact CE-CD2 3.6Å; M97-F102 HydrophobicContact CE-CE1 3.96Å; M97-F102 HydrophobicContact CE-CE2 3.7Å; M97-F102 HydrophobicContact CE-CG 3.71Å; M97-F102 HydrophobicContact CE-CZ 3.87Å; M97-F102 HydrophobicContact CG-CD2 4.31Å; M97-F102 HydrophobicContact CG-CE2 4.4Å; K100-F102 HydrophobicContact CB-CE2 3.76Å; K100-F102 HydrophobicContact CB-CZ 4.26Å; F102-Y104 HydrophobicContact CB-CD2 4.47Å; F102-Y104 HydrophobicContact CB-CE2 4.32Å; F102-W236 HydrophobicContact CE1-CZ2 4.36Å; F102-W236 HydrophobicContact CE2-CH2 4.27Å; F102-W236 AromaticContact CZ-CH2 3.61Å; F102-W236 HydrophobicContact CZ-CH2 3.61Å; F102-W236 AromaticContact CZ-CZ2 3.63Å; F102-W236 HydrophobicContact CZ-CZ2 3.63Å; F102-M378 HydrophobicContact CE1-SD 4.26Å; F102-Q397 CarbonylContact C-O 3.46Å; F102-Q397 VanDerWaalsContact CA-O 3.27Å; F102-Q397 WeakPolarHBondContact CA-O 3.45Å; F102-Q397 HydrophobicContact CD1-CB 3.89Å; F102-Q397 HydrophobicContact CE1-CB 3.99Å
103T98.7Very high95.9Very high0 Ų023.3 Ų23.30%013%0.134CC..EExtended strand (participates in β ladder)trans-125.4112.2172.2-57.30000108.7P58 V92 F93 S94 I392 H396 Q397 V398 C399P58-T103 HydrophobicContact CB-CG2 4.43Å; P58-T103 HydrophobicContact CG-CG2 4.06Å; V92-T103 HydrophobicContact CG1-CG2 4.14Å; F93-T103 CarbonylContact O-C 3.58Å; F93-T103 VanDerWaalsContact O-CA 3.3Å; F93-T103 WeakPolarHBondContact O-CA 3.33Å; S94-T103 PolarHBondContact OG-OG1 3.47Å; T103-I392 HydrophobicContact CG2-CD1 3.92Å; T103-I392 HydrophobicContact CG2-CG1 4.12Å; T103-I392 HydrophobicContact CG2-CG2 4.39Å; T103-H396 PolarHBondContact OG1-ND1 3.08Å; T103-Q397 PolarHBondContact N-O 3.01Å; T103-V398 CarbonylContact O-C 3.56Å; T103-V398 WeakPolarHBondContact O-CA 3.47Å; T103-C399 PolarHBondContact O-N 3.28Å
104Y98.6Very high95.9Very high3 Ų323.6 Ų23.61%0.01214%0.136CC..EExtended strand (participates in β ladder)trans-88.8141.4179.8-89.3-101.9000111F74 L82 V92 F93 F95 F102 L106 T376 C399F74-Y104 HydrophobicContact CE2-CE2 4.39Å; F74-Y104 WeakPolarHBondContact CZ-OH 3.4Å; L82-Y104 HydrophobicContact CD1-CD1 3.98Å; L82-Y104 HydrophobicContact CD1-CE1 3.53Å; L82-Y104 HydrophobicContact CD2-CD1 3.57Å; L82-Y104 HydrophobicContact CD2-CD2 3.93Å; L82-Y104 HydrophobicContact CD2-CE1 3.71Å; L82-Y104 HydrophobicContact CD2-CE2 4.05Å; L82-Y104 HydrophobicContact CD2-CG 3.67Å; L82-Y104 HydrophobicContact CG-CD1 4.44Å; L82-Y104 HydrophobicContact CG-CE1 4.28Å; V92-Y104 WeakPolarHBondContact CA-O 3.08Å; F93-Y104 HydrophobicContact CE2-CG 4.43Å; F93-Y104 PolarHBondContact N-O 2.85Å; F93-Y104 PolarHBondContact O-N 3.3Å; F95-Y104 HydrophobicContact CD1-CD2 4.5Å; F95-Y104 AromaticContact CE1-CD2 3.45Å; F95-Y104 HydrophobicContact CE1-CD2 3.45Å; F95-Y104 VanDerWaalsContact CE1-CD2 3.45Å; F95-Y104 AromaticContact CE1-CE2 3.67Å; F95-Y104 HydrophobicContact CE1-CE2 3.67Å; F95-Y104 HydrophobicContact CE1-CG 4.46Å; F95-Y104 AromaticContact CZ-CD2 3.94Å; F95-Y104 HydrophobicContact CZ-CD2 3.94Å; F95-Y104 AromaticContact CZ-CE2 3.63Å; F95-Y104 HydrophobicContact CZ-CE2 3.63Å; F102-Y104 HydrophobicContact CB-CD2 4.47Å; F102-Y104 HydrophobicContact CB-CE2 4.32Å; Y104-L106 HydrophobicContact CD1-CD2 4Å; Y104-T376 HydrophobicContact CE1-CG2 4.18Å; Y104-T376 WeakPolarHBondContact OH-CG2 3.5Å; Y104-T376 PolarHBondContact OH-OG1 3.42Å; Y104-C399 CarbonylContact C-O 3.51Å; Y104-C399 WeakPolarHBondContact CA-O 3.26Å; Y104-C399 HydrophobicContact CD1-CB 3.72Å; Y104-C399 HydrophobicContact CD2-CB 3.7Å; Y104-C399 HydrophobicContact CE1-CB 3.61Å; Y104-C399 HydrophobicContact CE2-CB 3.61Å; Y104-C399 HydrophobicContact CG-CB 3.79Å
105L98.4Very high95.8Very high0 Ų023.8 Ų23.80%014%0.136CC..EExtended strand (participates in β ladder)trans-116.9102.4173.8-53.2178.4000107.2V92 A110 L113 M114 A387 I392 V398 C399 V400V92-L105 HydrophobicContact CB-CD2 4.49Å; V92-L105 HydrophobicContact CG1-CD2 3.96Å; V92-L105 HydrophobicContact CG2-CD2 3.89Å; L105-A110 HydrophobicContact CB-CB 4.05Å; L105-L113 HydrophobicContact CD1-CB 4.07Å; L105-L113 HydrophobicContact CD1-CD2 4.03Å; L105-L113 HydrophobicContact CD1-CG 4.33Å; L105-M114 HydrophobicContact CD1-CB 4.26Å; L105-A387 HydrophobicContact CD2-CB 3.98Å; L105-I392 HydrophobicContact CD2-CD1 4.02Å; L105-V398 HydrophobicContact CD1-CG1 3.46Å; L105-V398 VanDerWaalsContact CD1-CG1 3.46Å; L105-V398 HydrophobicContact CG-CG1 3.84Å; L105-C399 PolarHBondContact N-O 2.93Å; L105-V400 HydrophobicContact CB-CG2 4.03Å
106L98Very high95.7Very high1 Ų128.2 Ų28.21%0.00516%0.16CC..  trans-111.3140.6-176.5-59.1-176.1000110.6L82 Y86 P91 F93 Y104 A110 V404L82-L106 HydrophobicContact CB-CD1 4.32Å; Y86-L106 HydrophobicContact CD2-CB 3.78Å; Y86-L106 HydrophobicContact CD2-CD1 4.13Å; Y86-L106 HydrophobicContact CE2-CB 4.25Å; Y86-L106 HydrophobicContact CG-CD1 4.43Å; P91-L106 WeakPolarHBondContact CB-O 3.43Å; P91-L106 PolarHBondContact O-N 3.13Å; F93-L106 HydrophobicContact CE1-CD1 3.62Å; F93-L106 HydrophobicContact CE1-CG 4.3Å; F93-L106 HydrophobicContact CZ-CD1 3.72Å; F93-L106 HydrophobicContact CZ-CG 4.47Å; Y104-L106 HydrophobicContact CD1-CD2 4Å; L106-A110 WeakPolarHBondContact O-CB 3.17Å; L106-V404 HydrophobicContact CD1-CG1 4.07Å; L106-V404 HydrophobicContact CD2-CB 4.14Å; L106-V404 HydrophobicContact CD2-CG1 4.11Å
107G95.9Very high95.7Very high10 Ų1028.2 Ų28.210%0.10316%0.16CC..SBendtrans88.8162.2-171.700000112.6A111 N405G107-A111 WeakPolarHBondContact O-CB 3.29Å; G107-A111 PolarHBondContact O-N 2.69Å; G107-N405 PolarHBondContact N-OD1 3.43Å; G107-N405 PolarHBondContact O-ND2 2.84Å
108S93.9Very high95.9Very high18 Ų1833 Ų3313%0.12618%0.181CC..Hα-helixtrans-62-46.6-173.3-176.30000111.9A111 T112 F431S108-A111 PolarHBondContact O-N 3.37Å; S108-T112 PolarHBondContact O-N 3.19Å; S108-T112 VanDerWaalsContact O-N 3.1Å; S108-T112 PolarHBondContact O-OG1 2.78Å; S108-F431 PolarHBondContact OG-N 3.34Å; S108-F431 VanDerWaalsContact OG-N 3.1Å
109D95.1Very high96.2Very high144 Ų14432 Ų3277%0.7718%0.175SC*.Hα-helixtrans-64.6-47.8-176.4-68.8-9000112.4T112D109-T112 VanDerWaalsContact O-CB 3.22Å; D109-T112 WeakPolarHBondContact O-CB 3.4Å; D109-T112 PolarHBondContact O-N 3.3Å; D109-T112 PolarHBondContact O-OG1 2.91Å
110A96.5Very high96.6Very high6 Ų635.9 Ų35.95%0.0519%0.186CC..Hα-helixtrans-66.5-42.7178.400000111.7P91 V92 L105 L106 T112 L113P91-A110 HydrophobicContact CB-CB 4.06Å; V92-A110 HydrophobicContact CG2-CB 3.86Å; L105-A110 HydrophobicContact CB-CB 4.05Å; L106-A110 WeakPolarHBondContact O-CB 3.17Å; A110-T112 PolarHBondContact O-N 3.18Å; A110-L113 PolarHBondContact O-N 2.8Å
111A96.8Very high96.9Very high0 Ų032.9 Ų32.90%018%0.175CC..Hα-helixtrans-65.4-21.1-179.300000113.3G107 S108 L113 M114 F115 V400G107-A111 WeakPolarHBondContact O-CB 3.29Å; G107-A111 PolarHBondContact O-N 2.69Å; S108-A111 PolarHBondContact O-N 3.37Å; A111-L113 PolarHBondContact O-N 3.08Å; A111-M114 PolarHBondContact O-N 2.79Å; A111-M114 VanDerWaalsContact O-N 3.09Å; A111-F115 HydrophobicContact CB-CD2 4.21Å; A111-F115 HydrophobicContact CB-CE2 3.92Å; A111-F115 VanDerWaalsContact O-CD2 3.31Å; A111-F115 WeakPolarHBondContact O-CD2 3.26Å; A111-F115 PolarHBondContact O-N 2.87Å; A111-V400 HydrophobicContact CB-CG1 3.99Å; A111-V400 HydrophobicContact CB-CG2 3.81Å
112T95.6Very high96.9Very high43 Ų4331.4 Ų31.426%0.26417%0.166SC..Hα-helixtrans-51.8-38175.4-64.80000112.2S108 D109 A110 M114 F115 N116 F431S108-T112 PolarHBondContact O-N 3.19Å; S108-T112 VanDerWaalsContact O-N 3.1Å; S108-T112 PolarHBondContact O-OG1 2.78Å; D109-T112 VanDerWaalsContact O-CB 3.22Å; D109-T112 WeakPolarHBondContact O-CB 3.4Å; D109-T112 PolarHBondContact O-N 3.3Å; D109-T112 PolarHBondContact O-OG1 2.91Å; A110-T112 PolarHBondContact O-N 3.18Å; T112-M114 PolarHBondContact O-N 3.07Å; T112-F115 PolarHBondContact O-N 3.22Å; T112-N116 VanDerWaalsContact CG2-ND2 3.26Å; T112-N116 WeakPolarHBondContact CG2-ND2 3.15Å; T112-N116 WeakPolarHBondContact O-CB 3.38Å; T112-N116 PolarHBondContact O-N 3.49Å; T112-F431 HydrophobicContact CG2-CE2 4.03Å; T112-F431 VanDerWaalsContact OG1-CD2 3.28Å; T112-F431 WeakPolarHBondContact OG1-CD2 3.5Å; T112-F431 VanDerWaalsContact OG1-CE2 3.31Å; T112-F431 WeakPolarHBondContact OG1-CE2 3.35Å
113L97Very high97Very high31 Ų3131.5 Ų31.516%0.16217%0.166CC..Hα-helixtrans-54.7-53.3177.1172.364.3000111.1L105 A110 A111 F115 S117 L122 Q385 A387 I392L105-L113 HydrophobicContact CD1-CB 4.07Å; L105-L113 HydrophobicContact CD1-CD2 4.03Å; L105-L113 HydrophobicContact CD1-CG 4.33Å; A110-L113 PolarHBondContact O-N 2.8Å; A111-L113 PolarHBondContact O-N 3.08Å; L113-F115 PolarHBondContact O-N 3.47Å; L113-S117 VanDerWaalsContact O-CB 3.24Å; L113-S117 WeakPolarHBondContact O-CB 3.26Å; L113-S117 PolarHBondContact O-N 3.13Å; L113-S117 PolarHBondContact O-OG 2.99Å; L113-L122 HydrophobicContact CG-CD1 4.18Å; L113-Q385 HydrophobicContact CD1-CB 4.31Å; L113-Q385 HydrophobicContact CD2-CB 3.89Å; L113-A387 HydrophobicContact CB-CB 4.37Å; L113-A387 HydrophobicContact CD2-CB 3.69Å; L113-I392 HydrophobicContact CD2-CD1 3.91Å
114M97.5Very high96.9Very high6 Ų631.5 Ų31.53%0.0317%0.166CC..Hα-helixtrans-65.9-39.4-177178179.8-69.900112.7L105 A111 T112 S117 L122 M377 R379 V398 V400L105-M114 HydrophobicContact CD1-CB 4.26Å; A111-M114 PolarHBondContact O-N 2.79Å; A111-M114 VanDerWaalsContact O-N 3.09Å; T112-M114 PolarHBondContact O-N 3.07Å; M114-S117 PolarHBondContact O-OG 3.04Å; M114-L122 HydrophobicContact CB-CD1 4.45Å; M114-M377 HydrophobicContact SD-CB 4.15Å; M114-R379 HydrophobicContact CE-CB 4.48Å; M114-R379 HydrophobicContact CE-CG 4.18Å; M114-R379 HydrophobicContact CG-CG 4.17Å; M114-R379 HydrophobicContact SD-CG 4.35Å; M114-V398 VanDerWaalsContact CE-C 3.44Å; M114-V398 HydrophobicContact CE-CB 4.34Å; M114-V398 HydrophobicContact CE-CG1 4.04Å; M114-V398 WeakPolarHBondContact CE-O 3.34Å; M114-V400 HydrophobicContact CB-CG2 3.85Å; M114-V400 HydrophobicContact CE-CB 4.33Å; M114-V400 HydrophobicContact CE-CG2 3.93Å; M114-V400 HydrophobicContact CG-CG2 4.29Å; M114-V400 HydrophobicContact SD-CB 3.85Å; M114-V400 HydrophobicContact SD-CG2 3.61Å
115F96Very high96.8Very high6 Ų632.1 Ų32.13%0.02617%0.169CC..Hα-helixtrans-78.6-25.1-174.9-65.9-54.1000113.4A111 T112 L113 M377 V400 F431 I434 A438 G439A111-F115 HydrophobicContact CB-CD2 4.21Å; A111-F115 HydrophobicContact CB-CE2 3.92Å; A111-F115 VanDerWaalsContact O-CD2 3.31Å; A111-F115 WeakPolarHBondContact O-CD2 3.26Å; A111-F115 PolarHBondContact O-N 2.87Å; T112-F115 PolarHBondContact O-N 3.22Å; L113-F115 PolarHBondContact O-N 3.47Å; F115-M377 HydrophobicContact CE1-CE 3.81Å; F115-M377 HydrophobicContact CE1-SD 3.94Å; F115-M377 HydrophobicContact CZ-CE 3.59Å; F115-M377 HydrophobicContact CZ-SD 4.33Å; F115-V400 HydrophobicContact CE2-CG1 3.96Å; F115-V400 HydrophobicContact CE2-CG2 4.49Å; F115-V400 HydrophobicContact CZ-CB 4.35Å; F115-V400 HydrophobicContact CZ-CG1 3.84Å; F115-F431 HydrophobicContact CB-CD1 4.5Å; F115-F431 HydrophobicContact CB-CE1 3.97Å; F115-F431 HydrophobicContact CB-CZ 4.06Å; F115-F431 HydrophobicContact CD2-CB 4.37Å; F115-F431 AromaticContact CD2-CD1 3.76Å; F115-F431 HydrophobicContact CD2-CD1 3.76Å; F115-F431 HydrophobicContact CD2-CE1 4.1Å; F115-F431 AromaticContact CD2-CG 3.97Å; F115-F431 HydrophobicContact CD2-CG 3.97Å; F115-F431 HydrophobicContact CE2-CB 4.48Å; F115-F431 HydrophobicContact CE2-CD1 4.4Å; F115-F431 HydrophobicContact CG-CD1 4.36Å; F115-F431 HydrophobicContact CG-CE1 4.29Å; F115-I434 HydrophobicContact CE2-CD1 3.6Å; F115-I434 HydrophobicContact CE2-CG2 4.3Å; F115-I434 HydrophobicContact CZ-CD1 3.6Å; F115-A438 HydrophobicContact CB-CB 3.97Å; F115-A438 HydrophobicContact CD1-CB 3.76Å; F115-A438 HydrophobicContact CD2-CB 4.4Å; F115-A438 HydrophobicContact CE1-CB 4.39Å; F115-A438 HydrophobicContact CG-CB 3.78Å; F115-G439 WeakPolarHBondContact O-CA 3.45Å
116N96.1Very high96.7Very high93 Ų9335.4 Ų35.450%0.49719%0.187SC..Hα-helixtrans-94.8-19.1177.9-68.7-11.1000113.4T112 R440T112-N116 VanDerWaalsContact CG2-ND2 3.26Å; T112-N116 WeakPolarHBondContact CG2-ND2 3.15Å; T112-N116 WeakPolarHBondContact O-CB 3.38Å; T112-N116 PolarHBondContact O-N 3.49Å; N116-R440 PolarHBondContact O-NH1 2.92Å
117S96.5Very high96.5Very high19 Ų1935.7 Ų35.713%0.13319%0.189CC..SBendtrans-58149-177.961.30000112.5L113 M114 L122 R440L113-S117 VanDerWaalsContact O-CB 3.24Å; L113-S117 WeakPolarHBondContact O-CB 3.26Å; L113-S117 PolarHBondContact O-N 3.13Å; L113-S117 PolarHBondContact O-OG 2.99Å; M114-S117 PolarHBondContact O-OG 3.04Å; S117-L122 WeakPolarHBondContact OG-CB 3.37Å; S117-R440 PolarHBondContact O-NH1 3.09Å
118K96.9Very high96.5Very high116 Ų11636.8 Ų36.850%0.50419%0.19SC..  trans-77.8159.5166.7-48.7-179.7175.6172.50109.8E120 D121 L122K118-E120 WeakPolarHBondContact CB-OE2 3.39Å; K118-E120 PolarHBondContact O-N 3.28Å; K118-D121 PolarHBondContact O-N 3.03Å; K118-L122 PolarHBondContact O-N 2.94Å; K118-L122 VanDerWaalsContact O-N 3.09Å
119N97.1Very high96.5Very high6 Ų637.7 Ų37.73%0.03220%0.196CC..THydrogen-bonded Turntrans-78.3-14.7-175.7-167.576.1000112.4D121 N123 A124 E125 N146 H441N119-D121 VanDerWaalsContact C-N 3.29Å; N119-N123 PolarHBondContact ND2-ND2 3.18Å; N119-N123 VanDerWaalsContact O-CA 3.26Å; N119-N123 WeakPolarHBondContact O-CA 3.49Å; N119-N123 WeakPolarHBondContact O-CB 3.31Å; N119-N123 PolarHBondContact O-ND2 3.12Å; N119-A124 PolarHBondContact OD1-N 3.44Å; N119-E125 VanDerWaalsContact ND2-CD 3.35Å; N119-E125 PolarHBondContact ND2-OE1 3.33Å; N119-E125 PolarHBondContact ND2-OE2 3.29Å; N119-N146 HydrophobicContact CB-CB 4.15Å; N119-N146 WeakPolarHBondContact ND2-CB 3.38Å; N119-H441 PolarHBondContact OD1-NE2 3.23Å
120E96.9Very high96.2Very high108 Ų10834.3 Ų34.351%0.50518%0.175SC..THydrogen-bonded Turntrans-71.2-27.4171.1-58.672.8-154.100111.7K118 R382K118-E120 WeakPolarHBondContact CB-OE2 3.39Å; K118-E120 PolarHBondContact O-N 3.28Å; E120-R382 VanDerWaalsContact O-CB 3.31Å; E120-R382 WeakPolarHBondContact O-CB 3.4Å
121D97.7Very high95.9Very high46 Ų4634.6 Ų34.625%0.24618%0.175CC..THydrogen-bonded Turntrans-93.1-54.2-179.6-64.3-51.5000111.9K118 N119 R382 T383K118-D121 PolarHBondContact O-N 3.03Å; N119-D121 VanDerWaalsContact C-N 3.29Å; D121-R382 PolarHBondContact O-N 3.49Å; D121-T383 WeakPolarHBondContact CA-OG1 3.39Å; D121-T383 WeakPolarHBondContact CB-OG1 3.18Å; D121-T383 PolarHBondContact OD1-OG1 3.07Å
122L98.4Very high95.8Very high1 Ų135.1 Ų35.11%0.00518%0.178CC..EExtended strand (participates in β ladder)trans-116.796.3176.2-70-172.4000108.8L113 M114 S117 K118 R379 M380 A381 Q385 V398L113-L122 HydrophobicContact CG-CD1 4.18Å; M114-L122 HydrophobicContact CB-CD1 4.45Å; S117-L122 WeakPolarHBondContact OG-CB 3.37Å; K118-L122 PolarHBondContact O-N 2.94Å; K118-L122 VanDerWaalsContact O-N 3.09Å; L122-R379 HydrophobicContact CB-CB 3.74Å; L122-R379 HydrophobicContact CB-CG 4.03Å; L122-R379 WeakPolarHBondContact O-CD 3.27Å; L122-M380 CarbonylContact C-O 3.47Å; L122-M380 WeakPolarHBondContact CA-O 3.42Å; L122-A381 HydrophobicContact CD2-CB 3.93Å; L122-Q385 HydrophobicContact CD2-CG 3.78Å; L122-Q385 HydrophobicContact CG-CG 4.1Å; L122-V398 HydrophobicContact CD1-CG1 4.39Å; L122-V398 HydrophobicContact CD2-CB 4.17Å; L122-V398 HydrophobicContact CD2-CG2 3.77Å
123N98.5Very high95.8Very high4 Ų434.1 Ų34.12%0.02117%0.172CC..EExtended strand (participates in β ladder)trans-90.6131-167.2-172.1-89.5000112.9N119 E125 D126 R379 M380 R382N119-N123 PolarHBondContact ND2-ND2 3.18Å; N119-N123 VanDerWaalsContact O-CA 3.26Å; N119-N123 WeakPolarHBondContact O-CA 3.49Å; N119-N123 WeakPolarHBondContact O-CB 3.31Å; N119-N123 PolarHBondContact O-ND2 3.12Å; N123-E125 VanDerWaalsContact CG-OE2 3.23Å; N123-E125 PolarHBondContact ND2-OE2 3Å; N123-E125 PolarHBondContact OD1-N 3.13Å; N123-E125 VanDerWaalsContact OD1-N 3.09Å; N123-E125 PolarHBondContact OD1-OE2 3.48Å; N123-E125 VanDerWaalsContact OD1-OE2 3.12Å; N123-D126 HydrophobicContact CB-CB 4.46Å; N123-D126 WeakPolarHBondContact OD1-CB 3.46Å; N123-D126 PolarHBondContact OD1-N 2.69Å; N123-D126 PolarHBondContact OD1-OD1 2.95Å; N123-D126 PolarHBondContact OD1-OD2 3.02Å; N123-R379 CarbonylContact O-C 3.48Å; N123-R379 VanDerWaalsContact O-CA 3.31Å; N123-R379 WeakPolarHBondContact O-CA 3.13Å; N123-M380 PolarHBondContact N-O 2.91Å; N123-M380 PolarHBondContact O-N 2.84Å; N123-R382 HydrophobicContact CB-CG 4.06Å; N123-R382 VanDerWaalsContact CG-CZ 3.48Å
124A97.7Very high95.7Very high0 Ų034 Ų340%017%0.174CC..SBendtrans-84.3-39.5178.700000112.9N119 D126 V127 Y128 Y142 H441N119-A124 PolarHBondContact OD1-N 3.44Å; A124-D126 VanDerWaalsContact C-N 3.31Å; A124-D126 PolarHBondContact O-N 3.41Å; A124-V127 PolarHBondContact O-N 2.73Å; A124-V127 VanDerWaalsContact O-N 3.12Å; A124-Y128 HydrophobicContact CB-CD2 4.14Å; A124-Y128 HydrophobicContact CB-CE2 4.36Å; A124-Y128 VanDerWaalsContact O-CD2 3.27Å; A124-Y128 WeakPolarHBondContact O-CD2 3.17Å; A124-Y128 PolarHBondContact O-N 3.18Å; A124-Y128 VanDerWaalsContact O-N 3.09Å; A124-Y142 HydrophobicContact CB-CD1 4.24Å; A124-Y142 HydrophobicContact CB-CE1 3.86Å; A124-H441 VanDerWaalsContact CB-CE1 3.45Å; A124-H441 WeakPolarHBondContact CB-CE1 3.37Å
125E96.8Very high95.5Very high17 Ų1733.7 Ų33.78%0.07917%0.172CC..Hα-helixtrans-65.1-35.6-171.3-57.675.4-154.100111.6N119 N123 V127 Y128 S129 Y142 N146 H441N119-E125 VanDerWaalsContact ND2-CD 3.35Å; N119-E125 PolarHBondContact ND2-OE1 3.33Å; N119-E125 PolarHBondContact ND2-OE2 3.29Å; N123-E125 VanDerWaalsContact CG-OE2 3.23Å; N123-E125 PolarHBondContact ND2-OE2 3Å; N123-E125 PolarHBondContact OD1-N 3.13Å; N123-E125 VanDerWaalsContact OD1-N 3.09Å; N123-E125 PolarHBondContact OD1-OE2 3.48Å; N123-E125 VanDerWaalsContact OD1-OE2 3.12Å; E125-V127 PolarHBondContact O-N 2.96Å; E125-V127 VanDerWaalsContact O-N 3.15Å; E125-Y128 PolarHBondContact O-N 2.95Å; E125-S129 WeakPolarHBondContact O-CB 3.39Å; E125-S129 PolarHBondContact O-N 2.95Å; E125-S129 PolarHBondContact O-OG 2.81Å; E125-Y142 HydrophobicContact CG-CD1 4.11Å; E125-N146 PolarHBondContact OE1-ND2 3.45Å; E125-N146 VanDerWaalsContact OE1-ND2 3.09Å; E125-H441 IonicContact OE1-CE1 3.48Å
126D96.1Very high95.5Very high69 Ų6934.7 Ų34.737%0.36918%0.177SC..Hα-helixtrans-59.2-24.9175.9-74.6-12.8000113.7N123 A124 M380 R382N123-D126 HydrophobicContact CB-CB 4.46Å; N123-D126 WeakPolarHBondContact OD1-CB 3.46Å; N123-D126 PolarHBondContact OD1-N 2.69Å; N123-D126 PolarHBondContact OD1-OD1 2.95Å; N123-D126 PolarHBondContact OD1-OD2 3.02Å; A124-D126 VanDerWaalsContact C-N 3.31Å; A124-D126 PolarHBondContact O-N 3.41Å; D126-M380 HydrophobicContact CB-CB 3.56Å; D126-M380 HydrophobicContact CB-CG 4.05Å; D126-R382 IonicContact OD1-CZ 2.71Å; D126-R382 IonicContact OD1-NE 3.8Å; D126-R382 IonicContact OD1-NH2 3.83Å; D126-R382 PolarHBondContact OD1-NH2 3.08Å; D126-R382 IonicContact OD2-CZ 2.71Å; D126-R382 IonicContact OD2-NE 3.68Å; D126-R382 PolarHBondContact OD2-NE 3.05Å; D126-R382 IonicContact OD2-NH2 2.67Å; D126-R382 PolarHBondContact OD2-NH2 2.79Å; D126-R382 VanDerWaalsContact OD2-NH2 3.17Å
127V94.1Very high95.5Very high7 Ų730.5 Ų30.54%0.04216%0.155CC..Hα-helixtrans-97-43.8178.9-175.60000111A124 E125 M378 M380A124-V127 PolarHBondContact O-N 2.73Å; A124-V127 VanDerWaalsContact O-N 3.12Å; E125-V127 PolarHBondContact O-N 2.96Å; E125-V127 VanDerWaalsContact O-N 3.15Å; V127-M378 HydrophobicContact CG1-CB 3.9Å; V127-M378 HydrophobicContact CG1-CE 4.3Å; V127-M378 HydrophobicContact CG1-SD 4.32Å; V127-M380 HydrophobicContact CG2-CB 4.12Å
128Y94.9Very high95.5Very high33 Ų3336.8 Ų36.813%0.12918%0.18CC..Hα-helixtrans-95.7-28.8-166.5-61.6-52.7000115.2A124 E125 K130 L131 T132 Y142 M378A124-Y128 HydrophobicContact CB-CD2 4.14Å; A124-Y128 HydrophobicContact CB-CE2 4.36Å; A124-Y128 VanDerWaalsContact O-CD2 3.27Å; A124-Y128 WeakPolarHBondContact O-CD2 3.17Å; A124-Y128 PolarHBondContact O-N 3.18Å; A124-Y128 VanDerWaalsContact O-N 3.09Å; E125-Y128 PolarHBondContact O-N 2.95Å; Y128-K130 VanDerWaalsContact C-N 3.26Å; Y128-K130 PolarHBondContact O-N 3.39Å; Y128-K130 VanDerWaalsContact O-N 3.15Å; Y128-L131 PolarHBondContact O-N 2.95Å; Y128-T132 PolarHBondContact O-N 3.11Å; Y128-T132 PolarHBondContact O-OG1 3.06Å; Y128-Y142 HydrophobicContact CD2-CD1 4.44Å; Y128-Y142 HydrophobicContact CD2-CD2 4.42Å; Y128-Y142 HydrophobicContact CD2-CE1 4.04Å; Y128-Y142 HydrophobicContact CD2-CE2 4Å; Y128-Y142 AromaticContact CD2-CZ 3.8Å; Y128-Y142 HydrophobicContact CG-CD2 4.33Å; Y128-Y142 HydrophobicContact CG-CE2 4.16Å; Y128-M378 HydrophobicContact CE1-CE 3.91Å; Y128-M378 PolarHBondContact OH-N 3.45Å; Y128-M378 PolarHBondContact OH-O 3.16Å
129S94.3Very high95.5Very high37 Ų3732.2 Ų32.226%0.25917%0.166SC..Hα-helixtrans-50.8-44.6-174.956.50000112.9E125 L131 T132 T133 Y142E125-S129 WeakPolarHBondContact O-CB 3.39Å; E125-S129 PolarHBondContact O-N 2.95Å; E125-S129 PolarHBondContact O-OG 2.81Å; S129-L131 PolarHBondContact O-N 3.08Å; S129-T132 PolarHBondContact O-N 3.36Å; S129-T133 WeakPolarHBondContact O-CB 3.45Å; S129-T133 PolarHBondContact O-N 3.47Å; S129-T133 PolarHBondContact O-OG1 3.38Å; S129-T133 VanDerWaalsContact O-OG1 3.04Å; S129-Y142 WeakPolarHBondContact CB-O 3.19Å
130K89.8Confident95.6Very high73 Ų7332.1 Ų32.132%0.31717%0.165SC..Hα-helixtrans-57.4-34179.4-170.8-175.3172.8-163.10113.4Y128 P134 W236 L237 L238 T240Y128-K130 VanDerWaalsContact C-N 3.26Å; Y128-K130 PolarHBondContact O-N 3.39Å; Y128-K130 VanDerWaalsContact O-N 3.15Å; K130-P134 WeakPolarHBondContact O-CD 3.28Å; K130-W236 PolarHBondContact NZ-O 3.38Å; K130-L237 PolarHBondContact NZ-O 3.45Å; K130-L238 WeakPolarHBondContact CE-O 3.36Å; K130-L238 PolarHBondContact NZ-O 3.46Å; K130-T240 HydrophobicContact CG-CG2 4.05Å
131L89.4Confident95.6Very high11 Ų1127.6 Ų27.66%0.05815%0.146CC..Hα-helixtrans-86.7-45.3178.6-76174.3000111.8Y128 S129 A235 W236 M481Y128-L131 PolarHBondContact O-N 2.95Å; S129-L131 PolarHBondContact O-N 3.08Å; L131-A235 HydrophobicContact CD2-CB 3.6Å; L131-W236 HydrophobicContact CD1-CB 4.23Å; L131-W236 HydrophobicContact CD1-CG 4.38Å; L131-W236 HydrophobicContact CD2-CB 4.03Å; L131-W236 HydrophobicContact CG-CB 4.44Å; L131-M481 HydrophobicContact CD1-SD 4.38Å
132T94.4Very high95.6Very high11 Ų1127.7 Ų27.77%0.06714%0.144CC..Hα-helixtrans-87.7-35.7-168.155.60000113.6Y128 S129 V135 F136 Y142 F231Y128-T132 PolarHBondContact O-N 3.11Å; Y128-T132 PolarHBondContact O-OG1 3.06Å; S129-T132 PolarHBondContact O-N 3.36Å; T132-V135 PolarHBondContact O-N 3.01Å; T132-F136 HydrophobicContact CG2-CD2 4.37Å; T132-F136 HydrophobicContact CG2-CE2 3.73Å; T132-F136 HydrophobicContact CG2-CZ 4.26Å; T132-F136 PolarHBondContact O-N 3.47Å; T132-Y142 HydrophobicContact CG2-CD2 3.94Å; T132-Y142 HydrophobicContact CG2-CE2 4.34Å; T132-Y142 WeakPolarHBondContact OG1-CD2 3.37Å; T132-F231 HydrophobicContact CG2-CE1 4.01Å
133T95.8Very high95.5Very high22 Ų2230.7 Ų30.714%0.13516%0.16CC..Hα-helixtrans-60.2-42.7-177.3-60.90000112.4S129 V135 G137 K138 D143S129-T133 WeakPolarHBondContact O-CB 3.45Å; S129-T133 PolarHBondContact O-N 3.47Å; S129-T133 PolarHBondContact O-OG1 3.38Å; S129-T133 VanDerWaalsContact O-OG1 3.04Å; T133-V135 PolarHBondContact O-N 3.33Å; T133-G137 CarbonylContact O-C 3.57Å; T133-G137 WeakPolarHBondContact O-CA 3.1Å; T133-G137 PolarHBondContact O-N 3.06Å; T133-K138 HydrophobicContact CG2-CG 4.34Å; T133-D143 HydrophobicContact CG2-CB 4.01Å; T133-D143 WeakPolarHBondContact CG2-OD1 3.06Å; T133-D143 PolarHBondContact OG1-OD1 3.47Å
134P94.4Very high95.5Very high29 Ų2931.5 Ų31.519%0.18817%0.165CC..Hα-helixtrans-67.1-15.4175.9-22.335.6000114.6K130 T240K130-P134 WeakPolarHBondContact O-CD 3.28Å; P134-T240 HydrophobicContact CG-CG2 4.26Å
135V94.4Very high95.5Very high0 Ų035.8 Ų35.80%019%0.192CC..Hα-helixtrans-96.1-53.3-180179.50000110.7T132 T133 L227 F231 R250 H254 L307T132-V135 PolarHBondContact O-N 3.01Å; T133-V135 PolarHBondContact O-N 3.33Å; V135-L227 HydrophobicContact CG1-CB 4.33Å; V135-L227 HydrophobicContact CG1-CD2 4.24Å; V135-F231 HydrophobicContact CB-CE1 4.46Å; V135-F231 HydrophobicContact CB-CE2 4.31Å; V135-F231 HydrophobicContact CB-CZ 3.91Å; V135-F231 HydrophobicContact CG1-CE2 3.75Å; V135-F231 HydrophobicContact CG1-CZ 3.78Å; V135-F231 HydrophobicContact CG2-CE1 4.07Å; V135-F231 HydrophobicContact CG2-CE2 4.17Å; V135-F231 HydrophobicContact CG2-CZ 3.88Å; V135-R250 HydrophobicContact CG2-CG 4.23Å; V135-H254 PolarHBondContact O-CE1 3.24Å; V135-H254 PolarHBondContact O-ND1 2.93Å; V135-L307 HydrophobicContact CG1-CD1 3.48Å; V135-L307 VanDerWaalsContact CG1-CD1 3.48Å
136F95.9Very high95.5Very high27 Ų2735.4 Ų35.412%0.11819%0.191CC..Hα-helixtrans-81.5-27.9-177.6-54.2-27.3000112.5T132 V140 A141 F231 H254 G300 I303 L307T132-F136 HydrophobicContact CG2-CD2 4.37Å; T132-F136 HydrophobicContact CG2-CE2 3.73Å; T132-F136 HydrophobicContact CG2-CZ 4.26Å; T132-F136 PolarHBondContact O-N 3.47Å; F136-V140 HydrophobicContact CB-CG2 3.88Å; F136-A141 HydrophobicContact CD2-CB 3.88Å; F136-A141 HydrophobicContact CE2-CB 4.37Å; F136-F231 HydrophobicContact CE1-CE2 4.46Å; F136-F231 AromaticContact CE1-CZ 3.92Å; F136-F231 HydrophobicContact CE1-CZ 3.92Å; F136-F231 AromaticContact CZ-CZ 3.95Å; F136-F231 HydrophobicContact CZ-CZ 3.95Å; F136-H254 VanDerWaalsContact C-CE1 3.47Å; F136-H254 PolarHBondContact O-CE1 3.44Å; F136-G300 WeakPolarHBondContact O-CA 3.37Å; F136-I303 HydrophobicContact CD1-CG2 4.16Å; F136-L307 HydrophobicContact CD1-CD1 4.21Å; F136-L307 HydrophobicContact CE1-CB 4.3Å; F136-L307 HydrophobicContact CE1-CD1 3.8Å
137G95.9Very high95.6Very high4 Ų435.7 Ų35.74%0.04120%0.197CC..  trans102.4175-176.300000112.8T133 V140 H254T133-G137 CarbonylContact O-C 3.57Å; T133-G137 WeakPolarHBondContact O-CA 3.1Å; T133-G137 PolarHBondContact O-N 3.06Å; G137-V140 WeakPolarHBondContact O-CG2 3.3Å; G137-H254 WeakPolarHBondContact CA-CE1 3.28Å; G137-H254 PolarHBondContact N-CE1 2.7Å; G137-H254 VanDerWaalsContact N-CE1 3.31Å
138K96.6Very high95.8Very high151 Ų15138 Ų3866%0.65721%0.208SC*.THydrogen-bonded Turntrans-75.1159.1177.9-66.8-173.7176.7-175.90111.5T133 V140 D143T133-K138 HydrophobicContact CG2-CG 4.34Å; K138-V140 PolarHBondContact O-N 2.82Å; K138-D143 WeakPolarHBondContact CA-OD2 3.17Å; K138-D143 WeakPolarHBondContact CB-OD2 3.44Å
139G97.3Very high96Very high20 Ų2037.7 Ų37.721%0.20621%0.208CC..THydrogen-bonded Turntrans76.13.9174.500000114.8D143 V144 Q152G139-D143 PolarHBondContact N-OD2 3.49Å; G139-V144 VanDerWaalsContact O-CG1 3.32Å; G139-V144 WeakPolarHBondContact O-CG1 3.4Å; G139-Q152 PolarHBondContact O-NE2 2.84Å
140V97.9Very high96.1Very high4 Ų439.1 Ų39.12%0.02421%0.212CC..SBendtrans-133156.1-177.5-60.40000112.6F136 G137 K138 Y142 D143 E297 M301F136-V140 HydrophobicContact CB-CG2 3.88Å; G137-V140 WeakPolarHBondContact O-CG2 3.3Å; K138-V140 PolarHBondContact O-N 2.82Å; V140-Y142 PolarHBondContact O-N 3.44Å; V140-D143 WeakPolarHBondContact O-CB 3.46Å; V140-D143 PolarHBondContact O-N 2.93Å; V140-D143 VanDerWaalsContact O-N 3.11Å; V140-E297 HydrophobicContact CG1-CB 4.21Å; V140-E297 HydrophobicContact CG1-CG 4.41Å; V140-E297 WeakPolarHBondContact CG1-O 3.48Å; V140-M301 HydrophobicContact CB-CG 4.38Å; V140-M301 HydrophobicContact CG1-CG 3.83Å
141A96.9Very high96.5Very high13 Ų1336.9 Ų36.911%0.10720%0.203CC..G310 helixtrans54.6-118.317400000113.1F136 D143 V144 F149F136-A141 HydrophobicContact CD2-CB 3.88Å; F136-A141 HydrophobicContact CE2-CB 4.37Å; A141-D143 VanDerWaalsContact C-N 3.31Å; A141-D143 PolarHBondContact O-N 3.41Å; A141-V144 WeakPolarHBondContact O-CG2 3.2Å; A141-F149 HydrophobicContact CB-CE2 4.14Å
142Y97.5Very high96.9Very high48 Ų4836.5 Ų36.519%0.18820%0.2CC..G310 helixtrans-86.33.1-175.8-58.4-63.7000113.9A124 E125 Y128 S129 T132 V140 F149A124-Y142 HydrophobicContact CB-CD1 4.24Å; A124-Y142 HydrophobicContact CB-CE1 3.86Å; E125-Y142 HydrophobicContact CG-CD1 4.11Å; Y128-Y142 HydrophobicContact CD2-CD1 4.44Å; Y128-Y142 HydrophobicContact CD2-CD2 4.42Å; Y128-Y142 HydrophobicContact CD2-CE1 4.04Å; Y128-Y142 HydrophobicContact CD2-CE2 4Å; Y128-Y142 AromaticContact CD2-CZ 3.8Å; Y128-Y142 HydrophobicContact CG-CD2 4.33Å; Y128-Y142 HydrophobicContact CG-CE2 4.16Å; S129-Y142 WeakPolarHBondContact CB-O 3.19Å; T132-Y142 HydrophobicContact CG2-CD2 3.94Å; T132-Y142 HydrophobicContact CG2-CE2 4.34Å; T132-Y142 WeakPolarHBondContact OG1-CD2 3.37Å; V140-Y142 PolarHBondContact O-N 3.44Å; Y142-F149 HydrophobicContact CD1-CE1 4.41Å; Y142-F149 AromaticContact CE1-CE1 3.93Å; Y142-F149 HydrophobicContact CE1-CE1 3.93Å
143D97.9Very high97Very high65 Ų6537 Ų3735%0.34820%0.202SC..G310 helixtrans-81.4-18.2172.6-166.660.1000112.9T133 K138 G139 V140 A141T133-D143 HydrophobicContact CG2-CB 4.01Å; T133-D143 WeakPolarHBondContact CG2-OD1 3.06Å; T133-D143 PolarHBondContact OG1-OD1 3.47Å; K138-D143 WeakPolarHBondContact CA-OD2 3.17Å; K138-D143 WeakPolarHBondContact CB-OD2 3.44Å; G139-D143 PolarHBondContact N-OD2 3.49Å; V140-D143 WeakPolarHBondContact O-CB 3.46Å; V140-D143 PolarHBondContact O-N 2.93Å; V140-D143 VanDerWaalsContact O-N 3.11Å; A141-D143 VanDerWaalsContact C-N 3.31Å; A141-D143 PolarHBondContact O-N 3.41Å
144V98Very high97Very high20 Ų2043 Ų4312%0.12123%0.226CC..SBendtrans-111.2159.7-175.6-65.10000111.8G139 A141 I148 F149G139-V144 VanDerWaalsContact O-CG1 3.32Å; G139-V144 WeakPolarHBondContact O-CG1 3.4Å; A141-V144 WeakPolarHBondContact O-CG2 3.2Å; V144-I148 HydrophobicContact CB-CB 4.12Å; V144-I148 HydrophobicContact CB-CG2 4.05Å; V144-I148 HydrophobicContact CG1-CG2 4.38Å; V144-I148 HydrophobicContact CG2-CB 4.05Å; V144-I148 HydrophobicContact CG2-CG2 3.93Å; V144-F149 HydrophobicContact CG2-CB 4.07Å
145P97.5Very high97Very high90 Ų9042.3 Ų42.358%0.58422%0.221SC*.  trans-56146171.4-25.435.3000112.2P147 I148 F149P145-P147 VanDerWaalsContact C-CD 3.44Å; P145-P147 VanDerWaalsContact C-N 3.34Å; P145-P147 VanDerWaalsContact O-N 3.16Å; P145-I148 WeakPolarHBondContact O-CB 3.28Å; P145-I148 PolarHBondContact O-N 2.99Å; P145-F149 PolarHBondContact O-N 3.45Å; P145-F149 VanDerWaalsContact O-N 3.16Å
146N97.6Very high97Very high9 Ų943.3 Ų43.35%0.04823%0.226CC..Hα-helixtrans-51.8-40.7-175.7-165.9-101.8000114.9N119 E125 I148 F149 L150 H441N119-N146 HydrophobicContact CB-CB 4.15Å; N119-N146 WeakPolarHBondContact ND2-CB 3.38Å; E125-N146 PolarHBondContact OE1-ND2 3.45Å; E125-N146 VanDerWaalsContact OE1-ND2 3.09Å; N146-I148 VanDerWaalsContact C-N 3.31Å; N146-I148 PolarHBondContact O-N 3.01Å; N146-F149 PolarHBondContact O-N 2.91Å; N146-L150 WeakPolarHBondContact O-CG 3.44Å; N146-L150 PolarHBondContact O-N 2.99Å; N146-H441 PolarHBondContact ND2-CE1 3.49Å; N146-H441 PolarHBondContact ND2-NE2 3.31Å
147P97.9Very high96.9Very high76 Ų7648.3 Ų48.349%0.49425%0.248SC..Hα-helixtrans-57.9-39.7175.8-26.736.7000113.9P145 L150 E151P145-P147 VanDerWaalsContact C-CD 3.44Å; P145-P147 VanDerWaalsContact C-N 3.34Å; P145-P147 VanDerWaalsContact O-N 3.16Å; P147-L150 PolarHBondContact O-N 3.27Å; P147-E151 PolarHBondContact O-N 2.64Å
148I98Very high96.6Very high55 Ų5551.9 Ų51.928%0.28227%0.268SS..Hα-helixtrans-68.2-42.8176.8-57.3-58.6000110.1V144 P145 N146 L150 E151 Q152 Y287V144-I148 HydrophobicContact CB-CB 4.12Å; V144-I148 HydrophobicContact CB-CG2 4.05Å; V144-I148 HydrophobicContact CG1-CG2 4.38Å; V144-I148 HydrophobicContact CG2-CB 4.05Å; V144-I148 HydrophobicContact CG2-CG2 3.93Å; P145-I148 WeakPolarHBondContact O-CB 3.28Å; P145-I148 PolarHBondContact O-N 2.99Å; N146-I148 VanDerWaalsContact C-N 3.31Å; N146-I148 PolarHBondContact O-N 3.01Å; I148-L150 VanDerWaalsContact C-N 3.3Å; I148-L150 PolarHBondContact O-N 3.26Å; I148-E151 WeakPolarHBondContact O-CB 3.44Å; I148-E151 PolarHBondContact O-N 3.33Å; I148-E151 VanDerWaalsContact O-N 3.12Å; I148-Q152 PolarHBondContact O-N 2.95Å; I148-Y287 HydrophobicContact CG2-CE1 3.83Å
149F98.1Very high96.1Very high26 Ų2644.7 Ų44.711%0.11424%0.237CC..Hα-helixtrans-62.4-36.7175.4-179.7-142.6000112.4A141 Y142 V144 P145 N146 E151 Q152 K153A141-F149 HydrophobicContact CB-CE2 4.14Å; Y142-F149 HydrophobicContact CD1-CE1 4.41Å; Y142-F149 AromaticContact CE1-CE1 3.93Å; Y142-F149 HydrophobicContact CE1-CE1 3.93Å; V144-F149 HydrophobicContact CG2-CB 4.07Å; P145-F149 PolarHBondContact O-N 3.45Å; P145-F149 VanDerWaalsContact O-N 3.16Å; N146-F149 PolarHBondContact O-N 2.91Å; F149-E151 VanDerWaalsContact C-N 3.29Å; F149-E151 PolarHBondContact O-N 3.38Å; F149-Q152 HydrophobicContact CD2-CB 4.41Å; F149-Q152 WeakPolarHBondContact O-CB 3.25Å; F149-Q152 PolarHBondContact O-N 2.82Å; F149-K153 HydrophobicContact CD1-CD 4.27Å; F149-K153 HydrophobicContact CD2-CD 4.39Å; F149-K153 HydrophobicContact CD2-CG 4.01Å; F149-K153 HydrophobicContact CE1-CD 3.86Å; F149-K153 HydrophobicContact CE1-CG 4.43Å; F149-K153 HydrophobicContact CE2-CD 3.97Å; F149-K153 HydrophobicContact CE2-CG 3.63Å; F149-K153 HydrophobicContact CZ-CD 3.7Å; F149-K153 HydrophobicContact CZ-CG 3.88Å; F149-K153 WeakPolarHBondContact O-CG 3.38Å; F149-K153 PolarHBondContact O-N 2.85Å
150L97.4Very high95.9Very high67 Ų6744.5 Ų44.535%0.35123%0.231SC..Hα-helixtrans-63.9-34.6174.5-69.8177.2000112.3N146 P147 I148 K154N146-L150 WeakPolarHBondContact O-CG 3.44Å; N146-L150 PolarHBondContact O-N 2.99Å; P147-L150 PolarHBondContact O-N 3.27Å; I148-L150 VanDerWaalsContact C-N 3.3Å; I148-L150 PolarHBondContact O-N 3.26Å; L150-K154 WeakPolarHBondContact O-CB 3.5Å; L150-K154 PolarHBondContact O-N 3.36Å
151E97.9Very high95.6Very high27 Ų2746.9 Ų46.913%0.12624%0.244CC..Hα-helixtrans-66.5-46.2172.2-69-178.1-144.600111.4P147 I148 F149 K153 K154 M155 Y287 K288P147-E151 PolarHBondContact O-N 2.64Å; I148-E151 WeakPolarHBondContact O-CB 3.44Å; I148-E151 PolarHBondContact O-N 3.33Å; I148-E151 VanDerWaalsContact O-N 3.12Å; F149-E151 VanDerWaalsContact C-N 3.29Å; F149-E151 PolarHBondContact O-N 3.38Å; E151-K153 VanDerWaalsContact C-N 3.33Å; E151-K153 PolarHBondContact O-N 3.2Å; E151-K154 WeakPolarHBondContact O-CA 3.4Å; E151-K154 WeakPolarHBondContact O-CB 3.48Å; E151-K154 PolarHBondContact O-N 3.28Å; E151-M155 WeakPolarHBondContact O-CG 3.41Å; E151-M155 PolarHBondContact O-N 2.74Å; E151-Y287 HydrophobicContact CB-CD1 3.98Å; E151-Y287 HydrophobicContact CB-CE1 4.28Å; E151-K288 HydrophobicContact CG-CD 4.46Å; E151-K288 HydrophobicContact CG-CG 4.49Å; E151-K288 WeakPolarHBondContact OE1-CD 3.37Å; E151-K288 IonicContact OE1-NZ 2.76Å; E151-K288 WeakPolarHBondContact OE2-CG 3.46Å; E151-K288 PolarHBondContact OE2-N 3.02Å
152Q97.6Very high95.4Very high2 Ų251 Ų511%0.00926%0.263CS..Hα-helixtrans-57.2-44.3173.7-68.4174.3-3.800112G139 I148 F149 K154 M155 L156 Y287 M301G139-Q152 PolarHBondContact O-NE2 2.84Å; I148-Q152 PolarHBondContact O-N 2.95Å; F149-Q152 HydrophobicContact CD2-CB 4.41Å; F149-Q152 WeakPolarHBondContact O-CB 3.25Å; F149-Q152 PolarHBondContact O-N 2.82Å; Q152-K154 VanDerWaalsContact C-N 3.3Å; Q152-K154 PolarHBondContact O-N 3.17Å; Q152-M155 PolarHBondContact O-N 3.21Å; Q152-L156 WeakPolarHBondContact O-CG 3.34Å; Q152-L156 PolarHBondContact O-N 3.32Å; Q152-Y287 HydrophobicContact CG-CE1 4.16Å; Q152-Y287 PolarHBondContact NE2-OH 3.41Å; Q152-M301 HydrophobicContact CB-CE 3.83Å; Q152-M301 HydrophobicContact CB-SD 4.22Å; Q152-M301 HydrophobicContact CG-CE 4.26Å; Q152-M301 HydrophobicContact CG-SD 4.03Å; Q152-M301 WeakPolarHBondContact O-CE 3.34Å
153K96.4Very high95.1Very high23 Ų2351.3 Ų51.310%0.128%0.276CS..Hα-helixtrans-61.4-38174.8-74.5-178.568.7166.40112.1F149 E151 K157 R440 R442 I444F149-K153 HydrophobicContact CD1-CD 4.27Å; F149-K153 HydrophobicContact CD2-CD 4.39Å; F149-K153 HydrophobicContact CD2-CG 4.01Å; F149-K153 HydrophobicContact CE1-CD 3.86Å; F149-K153 HydrophobicContact CE1-CG 4.43Å; F149-K153 HydrophobicContact CE2-CD 3.97Å; F149-K153 HydrophobicContact CE2-CG 3.63Å; F149-K153 HydrophobicContact CZ-CD 3.7Å; F149-K153 HydrophobicContact CZ-CG 3.88Å; F149-K153 WeakPolarHBondContact O-CG 3.38Å; F149-K153 PolarHBondContact O-N 2.85Å; E151-K153 VanDerWaalsContact C-N 3.33Å; E151-K153 PolarHBondContact O-N 3.2Å; K153-K157 VanDerWaalsContact O-CB 3.29Å; K153-K157 WeakPolarHBondContact O-CB 3.5Å; K153-K157 PolarHBondContact O-N 3.44Å; K153-R440 PolarHBondContact NZ-O 3.2Å; K153-R442 PolarHBondContact NZ-O 2.8Å; K153-I444 HydrophobicContact CB-CG2 4.4Å
154K95.8Very high94.8Very high146 Ų14648.7 Ų48.764%0.63526%0.262SS*.Hα-helixtrans-65-44.2176.7-173.7-176.7175.2-170.80110.8L150 E151 Q152 K157 T158L150-K154 WeakPolarHBondContact O-CB 3.5Å; L150-K154 PolarHBondContact O-N 3.36Å; E151-K154 WeakPolarHBondContact O-CA 3.4Å; E151-K154 WeakPolarHBondContact O-CB 3.48Å; E151-K154 PolarHBondContact O-N 3.28Å; Q152-K154 VanDerWaalsContact C-N 3.3Å; Q152-K154 PolarHBondContact O-N 3.17Å; K154-K157 PolarHBondContact O-N 2.8Å; K154-T158 PolarHBondContact O-N 3.48Å; K154-T158 VanDerWaalsContact O-N 3.09Å
155M95.2Very high94.6Very high16 Ų1648 Ų488%0.07926%0.257CS..Hα-helixtrans-62.6-42176.6-62.3163.1178.400112.1E151 Q152 K157 T158 L282 A285 T286 Y287 L293 M301E151-M155 WeakPolarHBondContact O-CG 3.41Å; E151-M155 PolarHBondContact O-N 2.74Å; Q152-M155 PolarHBondContact O-N 3.21Å; M155-K157 VanDerWaalsContact C-N 3.31Å; M155-K157 PolarHBondContact O-N 3.47Å; M155-T158 PolarHBondContact O-N 3.46Å; M155-T158 PolarHBondContact O-OG1 3.05Å; M155-L282 HydrophobicContact CB-CD2 4.32Å; M155-A285 HydrophobicContact CB-CB 4.3Å; M155-A285 HydrophobicContact CE-CB 4.41Å; M155-A285 HydrophobicContact CG-CB 3.92Å; M155-A285 HydrophobicContact SD-CB 3.99Å; M155-T286 VanDerWaalsContact CE-C 3.46Å; M155-T286 VanDerWaalsContact CE-O 3.25Å; M155-T286 WeakPolarHBondContact CE-O 3.31Å; M155-Y287 HydrophobicContact CE-CD1 3.68Å; M155-Y287 HydrophobicContact CE-CD2 4.44Å; M155-Y287 HydrophobicContact CE-CE1 4Å; M155-Y287 HydrophobicContact CE-CG 3.93Å; M155-L293 HydrophobicContact SD-CD1 3.92Å; M155-L293 HydrophobicContact SD-CD2 4.02Å; M155-L293 HydrophobicContact SD-CG 4.16Å; M155-M301 HydrophobicContact CB-CE 4.46Å
156L94.3Very high94.5Very high20 Ų2047.4 Ų47.411%0.10525%0.245CC..Hα-helixtrans-64.3-40.1174.1-71.1168.7000111.4Q152 T158 G159 L160 L282 M301 L305 I444Q152-L156 WeakPolarHBondContact O-CG 3.34Å; Q152-L156 PolarHBondContact O-N 3.32Å; L156-T158 VanDerWaalsContact C-N 3.31Å; L156-T158 PolarHBondContact O-N 3.47Å; L156-G159 PolarHBondContact O-N 3.24Å; L156-L160 WeakPolarHBondContact O-CG 3.36Å; L156-L160 PolarHBondContact O-N 3.02Å; L156-L282 HydrophobicContact CD2-CD1 4.32Å; L156-L282 HydrophobicContact CD2-CD2 4.13Å; L156-M301 HydrophobicContact CD1-CE 3.94Å; L156-M301 HydrophobicContact CD2-CE 3.94Å; L156-M301 HydrophobicContact CG-CE 3.56Å; L156-L305 HydrophobicContact CD2-CD1 4.44Å; L156-L305 HydrophobicContact CD2-CD2 4.09Å; L156-I444 HydrophobicContact CB-CD1 3.51Å; L156-I444 HydrophobicContact CD1-CD1 4.14Å; L156-I444 HydrophobicContact CG-CD1 4.49Å
157K93.4Very high94.3Very high133 Ų13351.7 Ų51.758%0.57827%0.265SS*.Hα-helixtrans-65.7-30.3-179.3-169.8179.4179.2-175.80112.9K153 K154 M155 G159 L160K153-K157 VanDerWaalsContact O-CB 3.29Å; K153-K157 WeakPolarHBondContact O-CB 3.5Å; K153-K157 PolarHBondContact O-N 3.44Å; K154-K157 PolarHBondContact O-N 2.8Å; M155-K157 VanDerWaalsContact C-N 3.31Å; M155-K157 PolarHBondContact O-N 3.47Å; K157-G159 VanDerWaalsContact C-N 3.25Å; K157-G159 PolarHBondContact O-N 3.25Å; K157-L160 PolarHBondContact O-N 3.39Å
158T90Very high94.2Very high78 Ų7848.6 Ų48.648%0.47924%0.244SC..Hα-helixtrans-63.6-33.3178.647.70000112.2K154 M155 L156 L160 N161 T281K154-T158 PolarHBondContact O-N 3.48Å; K154-T158 VanDerWaalsContact O-N 3.09Å; M155-T158 PolarHBondContact O-N 3.46Å; M155-T158 PolarHBondContact O-OG1 3.05Å; L156-T158 VanDerWaalsContact C-N 3.31Å; L156-T158 PolarHBondContact O-N 3.47Å; T158-L160 VanDerWaalsContact C-N 3.33Å; T158-N161 PolarHBondContact O-ND2 3.29Å; T158-T281 WeakPolarHBondContact OG1-CG2 3.38Å
159G86.4Confident94.2Very high0 Ų046 Ų460%023%0.231CC..THydrogen-bonded Turntrans-82.4-5.9172.400000114.5L156 K157 N161 H164L156-G159 PolarHBondContact O-N 3.24Å; K157-G159 VanDerWaalsContact C-N 3.25Å; K157-G159 PolarHBondContact O-N 3.25Å; G159-N161 PolarHBondContact O-N 3.48Å; G159-H164 PolarHBondContact O-ND1 3.08Å
160L91.6Very high94.1Very high17 Ų1749.8 Ų49.89%0.08925%0.247CC..SBendtrans-9865.3175.2-62.6177.2000110.5L156 K157 T158 F165 L207 I278 I444 F448L156-L160 WeakPolarHBondContact O-CG 3.36Å; L156-L160 PolarHBondContact O-N 3.02Å; K157-L160 PolarHBondContact O-N 3.39Å; T158-L160 VanDerWaalsContact C-N 3.33Å; L160-F165 VanDerWaalsContact C-CZ 3.48Å; L160-F165 HydrophobicContact CB-CE1 4.45Å; L160-F165 HydrophobicContact CB-CZ 4.06Å; L160-F165 HydrophobicContact CD2-CE1 4.39Å; L160-L207 HydrophobicContact CD2-CD2 3.87Å; L160-I278 HydrophobicContact CD2-CD1 4.33Å; L160-I444 HydrophobicContact CD1-CD1 4.4Å; L160-I444 HydrophobicContact CD1-CG1 4.28Å; L160-F448 HydrophobicContact CD2-CB 4.18Å; L160-F448 HydrophobicContact CD2-CG 4.48Å
161N91.3Very high94.1Very high54 Ų5449.3 Ų49.329%0.28924%0.244SC..SBendtrans-122.8168.5-173.972.158.8000112.3T158 G159 A163 H164 F165T158-N161 PolarHBondContact O-ND2 3.29Å; G159-N161 PolarHBondContact O-N 3.48Å; N161-A163 VanDerWaalsContact C-N 3.31Å; N161-A163 PolarHBondContact O-N 2.86Å; N161-A163 WeakPolarHBondContact OD1-CA 3.41Å; N161-A163 VanDerWaalsContact OD1-CB 3.32Å; N161-A163 WeakPolarHBondContact OD1-CB 3.47Å; N161-A163 PolarHBondContact OD1-N 3Å; N161-H164 PolarHBondContact ND2-CE1 3.45Å; N161-H164 PolarHBondContact ND2-ND1 3.49Å; N161-H164 PolarHBondContact O-N 3.06Å; N161-H164 PolarHBondContact OD1-N 3.41Å; N161-H164 VanDerWaalsContact OD1-N 3.13Å; N161-F165 WeakPolarHBondContact O-CD2 3.45Å; N161-F165 WeakPolarHBondContact O-CG 3.29Å; N161-F165 PolarHBondContact O-N 3.31Å
162I93.4Very high94.1Very high98 Ų9848 Ų4850%0.50324%0.238SC..Hα-helixtrans-61.3-36.3-175.8-68.3169.2000112.6F165 K166 F351I162-F165 PolarHBondContact O-N 3.01Å; I162-K166 WeakPolarHBondContact O-CG 3.22Å; I162-K166 PolarHBondContact O-N 2.87Å; I162-F351 HydrophobicContact CB-CE1 4.45Å; I162-F351 HydrophobicContact CG1-CE1 4.27Å; I162-F351 HydrophobicContact CG1-CZ 4.23Å; I162-F351 HydrophobicContact CG2-CD1 4.22Å; I162-F351 HydrophobicContact CG2-CE1 3.67Å; I162-F351 HydrophobicContact CG2-CZ 4.31Å
163A90.9Very high94.1Very high56 Ų5649.3 Ų49.346%0.46324%0.244SC..Hα-helixtrans-62.3-48-179.900000110.6N161 F165 K166N161-A163 VanDerWaalsContact C-N 3.31Å; N161-A163 PolarHBondContact O-N 2.86Å; N161-A163 WeakPolarHBondContact OD1-CA 3.41Å; N161-A163 VanDerWaalsContact OD1-CB 3.32Å; N161-A163 WeakPolarHBondContact OD1-CB 3.47Å; N161-A163 PolarHBondContact OD1-N 3Å; A163-F165 PolarHBondContact O-N 3.18Å; A163-K166 PolarHBondContact O-N 3.09Å
164H91.5Very high94.2Very high10 Ų1051.9 Ų51.95%0.04627%0.266CS..Hα-helixtrans-65.9-37.9174.2-61.2149.6000112.5G159 N161 K166 E167 H168 D276G159-H164 PolarHBondContact O-ND1 3.08Å; N161-H164 PolarHBondContact ND2-CE1 3.45Å; N161-H164 PolarHBondContact ND2-ND1 3.49Å; N161-H164 PolarHBondContact O-N 3.06Å; N161-H164 PolarHBondContact OD1-N 3.41Å; N161-H164 VanDerWaalsContact OD1-N 3.13Å; H164-K166 VanDerWaalsContact C-N 3.27Å; H164-K166 PolarHBondContact O-N 3.28Å; H164-E167 PolarHBondContact O-N 3.39Å; H164-E167 VanDerWaalsContact O-N 3.1Å; H164-H168 PolarHBondContact O-CD2 3.35Å; H164-H168 PolarHBondContact O-N 2.87Å; H164-D276 IonicContact CD2-OD2 3.9Å; H164-D276 PolarHBondContact NE2-O 3.07Å; H164-D276 IonicContact NE2-OD1 3.44Å; H164-D276 PolarHBondContact NE2-OD1 3.33Å; H164-D276 VanDerWaalsContact NE2-OD1 3.14Å; H164-D276 IonicContact NE2-OD2 2.83Å
165F95.1Very high94.3Very high4 Ų446.5 Ų46.52%0.01824%0.242CC..Hα-helixtrans-61.6-33.6178.6-62.9-31.8000113.3L160 N161 I162 A163 E167 H168 V169 F351 N447 F448 V451L160-F165 VanDerWaalsContact C-CZ 3.48Å; L160-F165 HydrophobicContact CB-CE1 4.45Å; L160-F165 HydrophobicContact CB-CZ 4.06Å; L160-F165 HydrophobicContact CD2-CE1 4.39Å; N161-F165 WeakPolarHBondContact O-CD2 3.45Å; N161-F165 WeakPolarHBondContact O-CG 3.29Å; N161-F165 PolarHBondContact O-N 3.31Å; I162-F165 PolarHBondContact O-N 3.01Å; A163-F165 PolarHBondContact O-N 3.18Å; F165-E167 VanDerWaalsContact C-N 3.32Å; F165-E167 PolarHBondContact O-N 2.93Å; F165-H168 AromaticContact CD1-ND1 3.65Å; F165-H168 PolarHBondContact O-N 3.4Å; F165-V169 WeakPolarHBondContact O-CG2 3.48Å; F165-V169 PolarHBondContact O-N 3.31Å; F165-V169 VanDerWaalsContact O-N 3.15Å; F165-F351 HydrophobicContact CB-CD2 3.68Å; F165-F351 HydrophobicContact CB-CE2 3.44Å; F165-F351 VanDerWaalsContact CB-CE2 3.44Å; F165-F351 HydrophobicContact CB-CZ 4.14Å; F165-F351 HydrophobicContact CD2-CE2 4.06Å; F165-F351 HydrophobicContact CD2-CZ 4.26Å; F165-F351 HydrophobicContact CG-CE2 4.13Å; F165-N447 HydrophobicContact CE2-CB 3.66Å; F165-N447 HydrophobicContact CZ-CB 3.82Å; F165-F448 HydrophobicContact CE1-CB 3.9Å; F165-F448 HydrophobicContact CE1-CD2 4.16Å; F165-F448 HydrophobicContact CZ-CB 4.35Å; F165-V451 HydrophobicContact CB-CG2 4.17Å; F165-V451 HydrophobicContact CD1-CG2 4.4Å; F165-V451 HydrophobicContact CD2-CG2 4.46Å; F165-V451 HydrophobicContact CG-CG2 4.11Å
166K95.1Very high94.4Very high78 Ų7845.7 Ų45.734%0.33924%0.239SC..Hα-helixtrans-59.6-41.8173.2-73.6-176172.2-152.30112.5I162 A163 H164 F351 D352I162-K166 WeakPolarHBondContact O-CG 3.22Å; I162-K166 PolarHBondContact O-N 2.87Å; A163-K166 PolarHBondContact O-N 3.09Å; H164-K166 VanDerWaalsContact C-N 3.27Å; H164-K166 PolarHBondContact O-N 3.28Å; K166-F351 HydrophobicContact CB-CB 4.45Å; K166-F351 HydrophobicContact CG-CB 3.79Å; K166-F351 HydrophobicContact CG-CD1 4.1Å; K166-F351 HydrophobicContact CG-CG 4.07Å; K166-D352 IonicContact NZ-OD2 2.71Å; K166-D352 PolarHBondContact NZ-OD2 2.88Å
167E93.2Very high94.6Very high99 Ų9947.1 Ų47.146%0.46325%0.248SC..Hα-helixtrans-74.8-34.6175.9-65-52.6120.900112.3H164 F165 V169 K170 L171H164-E167 PolarHBondContact O-N 3.39Å; H164-E167 VanDerWaalsContact O-N 3.1Å; F165-E167 VanDerWaalsContact C-N 3.32Å; F165-E167 PolarHBondContact O-N 2.93Å; E167-V169 VanDerWaalsContact C-N 3.32Å; E167-V169 PolarHBondContact O-N 3.21Å; E167-K170 PolarHBondContact O-N 3.44Å; E167-K170 IonicContact OE1-NZ 2.72Å; E167-K170 PolarHBondContact OE1-NZ 3.21Å; E167-K170 IonicContact OE2-NZ 3.27Å; E167-K170 PolarHBondContact OE2-NZ 3.24Å; E167-L171 WeakPolarHBondContact O-CG 3.36Å; E167-L171 PolarHBondContact O-N 3.41Å
168H95.7Very high94.8Very high11 Ų1145.6 Ų45.65%0.05124%0.243CC..Hα-helixtrans-59.8-40.2177.7-65.5174.2000112.4H164 F165 K170 L171 I172 C206 F448 V451H164-H168 PolarHBondContact O-CD2 3.35Å; H164-H168 PolarHBondContact O-N 2.87Å; F165-H168 AromaticContact CD1-ND1 3.65Å; F165-H168 PolarHBondContact O-N 3.4Å; H168-K170 VanDerWaalsContact C-N 3.31Å; H168-K170 PolarHBondContact O-N 2.86Å; H168-L171 PolarHBondContact O-N 3.07Å; H168-I172 HydrophobicContact CB-CD1 4.08Å; H168-I172 WeakPolarHBondContact O-CB 3.49Å; H168-I172 VanDerWaalsContact O-CD1 3.28Å; H168-I172 WeakPolarHBondContact O-CD1 3.42Å; H168-I172 WeakPolarHBondContact O-CG1 3.46Å; H168-I172 PolarHBondContact O-N 3.04Å; H168-C206 HydrophobicContact CB-CB 4.38Å; H168-C206 VanDerWaalsContact CG-SG 3.57Å; H168-C206 PolarHBondContact NE2-O 3.39Å; H168-F448 AromaticContact ND1-CD2 3.78Å; H168-F448 AromaticContact ND1-CE2 3.75Å; H168-V451 HydrophobicContact CB-CG1 4.36Å
169V98.1Very high95.2Very high1 Ų142.8 Ų42.81%0.00622%0.224CC..Hα-helixtrans-55.2-48.1178.4175.80000111.1F165 E167 L171 I172 E173 L349 F351 L354 V451 T455F165-V169 WeakPolarHBondContact O-CG2 3.48Å; F165-V169 PolarHBondContact O-N 3.31Å; F165-V169 VanDerWaalsContact O-N 3.15Å; E167-V169 VanDerWaalsContact C-N 3.32Å; E167-V169 PolarHBondContact O-N 3.21Å; V169-L171 PolarHBondContact O-N 3.43Å; V169-I172 PolarHBondContact O-N 2.99Å; V169-E173 WeakPolarHBondContact O-CB 3.4Å; V169-E173 PolarHBondContact O-N 2.91Å; V169-L349 HydrophobicContact CG1-CB 3.71Å; V169-L349 WeakPolarHBondContact CG1-O 3.33Å; V169-F351 HydrophobicContact CG2-CB 4.05Å; V169-F351 HydrophobicContact CG2-CD2 4.28Å; V169-L354 HydrophobicContact CG1-CD1 4.4Å; V169-L354 HydrophobicContact CG2-CD1 3.52Å; V169-L354 HydrophobicContact CG2-CG 4.46Å; V169-V451 HydrophobicContact CG2-CG1 3.96Å; V169-T455 HydrophobicContact CG1-CG2 4.14Å
170K96.4Very high95.7Very high105 Ų10542.9 Ų42.946%0.45722%0.224SC..Hα-helixtrans-62.2-43.6179.5-57.4172.2-171.3162.10111.9E167 H168 S174E167-K170 PolarHBondContact O-N 3.44Å; E167-K170 IonicContact OE1-NZ 2.72Å; E167-K170 PolarHBondContact OE1-NZ 3.21Å; E167-K170 IonicContact OE2-NZ 3.27Å; E167-K170 PolarHBondContact OE2-NZ 3.24Å; H168-K170 VanDerWaalsContact C-N 3.31Å; H168-K170 PolarHBondContact O-N 2.86Å; K170-S174 WeakPolarHBondContact O-CB 3.16Å; K170-S174 PolarHBondContact O-N 2.73Å; K170-S174 VanDerWaalsContact O-N 3.08Å
171L95.8Very high95.9Very high57 Ų5749.4 Ų49.430%0.29825%0.247SC..Hα-helixtrans-65.1-46.2179-66.6173.9000111.4E167 H168 V169 S174 E175E167-L171 WeakPolarHBondContact O-CG 3.36Å; E167-L171 PolarHBondContact O-N 3.41Å; H168-L171 PolarHBondContact O-N 3.07Å; V169-L171 PolarHBondContact O-N 3.43Å; L171-S174 PolarHBondContact O-N 3.28Å; L171-E175 WeakPolarHBondContact O-CB 3.49Å; L171-E175 WeakPolarHBondContact O-CG 3.4Å; L171-E175 PolarHBondContact O-N 2.68Å
172I98.4Very high96.2Very high0 Ų053.5 Ų53.50%026%0.259CS..Hα-helixtrans-65.5-44.9-179.1-65.5156.1000110.6H168 V169 T176 T202 V451 Q452 T455 I456H168-I172 HydrophobicContact CB-CD1 4.08Å; H168-I172 WeakPolarHBondContact O-CB 3.49Å; H168-I172 VanDerWaalsContact O-CD1 3.28Å; H168-I172 WeakPolarHBondContact O-CD1 3.42Å; H168-I172 WeakPolarHBondContact O-CG1 3.46Å; H168-I172 PolarHBondContact O-N 3.04Å; V169-I172 PolarHBondContact O-N 2.99Å; I172-T176 VanDerWaalsContact O-CB 3.29Å; I172-T176 WeakPolarHBondContact O-CB 3.4Å; I172-T176 PolarHBondContact O-N 3.37Å; I172-T176 PolarHBondContact O-OG1 3.27Å; I172-T202 HydrophobicContact CB-CG2 4.39Å; I172-T202 HydrophobicContact CG1-CG2 4.37Å; I172-T202 HydrophobicContact CG2-CG2 4.07Å; I172-V451 HydrophobicContact CD1-CG1 4.16Å; I172-Q452 HydrophobicContact CD1-CB 4.24Å; I172-Q452 HydrophobicContact CD1-CG 4.41Å; I172-T455 HydrophobicContact CB-CG2 3.81Å; I172-T455 HydrophobicContact CG2-CG2 3.63Å; I172-I456 HydrophobicContact CG2-CD1 4.36Å; I172-I456 HydrophobicContact CG2-CG1 3.6Å
173E98.6Very high96.4Very high29 Ų2949.4 Ų49.414%0.13624%0.237CC..Hα-helixtrans-59.5-49177.6179.9174.5-128.700110.8V169 T176 V177 L349 T455V169-E173 WeakPolarHBondContact O-CB 3.4Å; V169-E173 PolarHBondContact O-N 2.91Å; E173-T176 PolarHBondContact O-N 3.44Å; E173-V177 WeakPolarHBondContact O-CG2 3.44Å; E173-V177 PolarHBondContact O-N 3.12Å; E173-L349 HydrophobicContact CG-CD1 4.46Å; E173-L349 WeakPolarHBondContact OE1-CG 3.42Å; E173-L349 PolarHBondContact OE1-N 3.32Å; E173-L349 VanDerWaalsContact OE1-N 3.11Å; E173-L349 PolarHBondContact OE2-N 2.93Å; E173-L349 VanDerWaalsContact OE2-N 3.08Å; E173-T455 HydrophobicContact CB-CG2 4.03Å
174S97.9Very high96.7Very high78 Ų7848.1 Ų48.155%0.54523%0.23SC..Hα-helixtrans-59.1-49.6179.3-177.10000112.6K170 L171 T176 V177 E178K170-S174 WeakPolarHBondContact O-CB 3.16Å; K170-S174 PolarHBondContact O-N 2.73Å; K170-S174 VanDerWaalsContact O-N 3.08Å; L171-S174 PolarHBondContact O-N 3.28Å; S174-T176 VanDerWaalsContact C-N 3.3Å; S174-T176 PolarHBondContact O-N 2.97Å; S174-V177 PolarHBondContact O-N 3.08Å; S174-E178 WeakPolarHBondContact O-CB 3.43Å; S174-E178 PolarHBondContact O-N 2.99Å
175E97.4Very high96.9Very high32 Ų3252.7 Ų52.715%0.1526%0.255CS..Hα-helixtrans-62.3-38.5177.3-68.2-86.6-163.600111.5L171 Y179 L198 T202 S205 R213L171-E175 WeakPolarHBondContact O-CB 3.49Å; L171-E175 WeakPolarHBondContact O-CG 3.4Å; L171-E175 PolarHBondContact O-N 2.68Å; E175-Y179 WeakPolarHBondContact O-CB 3.48Å; E175-Y179 PolarHBondContact O-N 3.44Å; E175-L198 HydrophobicContact CB-CD1 4.2Å; E175-T202 HydrophobicContact CB-CG2 3.75Å; E175-T202 HydrophobicContact CG-CG2 4.4Å; E175-S205 PolarHBondContact OE1-OG 2.97Å; E175-R213 VanDerWaalsContact CD-NH2 3.34Å; E175-R213 IonicContact OE1-CZ 3.66Å; E175-R213 VanDerWaalsContact OE1-CZ 3.32Å; E175-R213 IonicContact OE1-NE 2.75Å; E175-R213 PolarHBondContact OE1-NE 2.96Å; E175-R213 IonicContact OE1-NH2 3.44Å; E175-R213 PolarHBondContact OE1-NH2 3.05Å; E175-R213 VanDerWaalsContact OE1-NH2 3.08Å; E175-R213 IonicContact OE2-CZ 3.6Å; E175-R213 IonicContact OE2-NE 2.84Å; E175-R213 IonicContact OE2-NH2 3.66Å; E175-R213 PolarHBondContact OE2-NH2 3.3Å
176T98.6Very high97.1Very high0 Ų056.5 Ų56.50%028%0.281CS..Hα-helixtrans-65.8-47.9178.3-56.10000110.8I172 E173 S174 F180 L198 I456 T459 L460I172-T176 VanDerWaalsContact O-CB 3.29Å; I172-T176 WeakPolarHBondContact O-CB 3.4Å; I172-T176 PolarHBondContact O-N 3.37Å; I172-T176 PolarHBondContact O-OG1 3.27Å; E173-T176 PolarHBondContact O-N 3.44Å; S174-T176 VanDerWaalsContact C-N 3.3Å; S174-T176 PolarHBondContact O-N 2.97Å; T176-F180 HydrophobicContact CG2-CD2 3.96Å; T176-F180 HydrophobicContact CG2-CE2 4.35Å; T176-F180 WeakPolarHBondContact O-CB 3.38Å; T176-F180 WeakPolarHBondContact O-CD2 3.48Å; T176-F180 PolarHBondContact O-N 3.05Å; T176-L198 HydrophobicContact CG2-CD2 3.84Å; T176-I456 HydrophobicContact CG2-CG2 4.43Å; T176-T459 HydrophobicContact CG2-CG2 3.7Å; T176-L460 HydrophobicContact CG2-CD2 4.32Å; T176-L460 HydrophobicContact CG2-CG 4.37Å
177V98.2Very high97.2Very high50 Ų5054 Ų5430%0.30328%0.278SS..Hα-helixtrans-60.1-49.5177170.60000110.5E173 S174 Y179 F180 R181 T459E173-V177 WeakPolarHBondContact O-CG2 3.44Å; E173-V177 PolarHBondContact O-N 3.12Å; S174-V177 PolarHBondContact O-N 3.08Å; V177-Y179 PolarHBondContact O-N 3.18Å; V177-F180 PolarHBondContact O-N 2.72Å; V177-R181 WeakPolarHBondContact O-CG 3.29Å; V177-R181 PolarHBondContact O-N 3.14Å; V177-T459 HydrophobicContact CG2-CG2 3.65Å
178E97.5Very high97.5Very high101 Ų10153.3 Ų53.347%0.47227%0.274SS..Hα-helixtrans-59.7-49.8-178.9-17161.3-129.600111.4S174 F180 R181S174-E178 WeakPolarHBondContact O-CB 3.43Å; S174-E178 PolarHBondContact O-N 2.99Å; E178-F180 VanDerWaalsContact C-N 3.34Å; E178-F180 PolarHBondContact O-N 3.24Å; E178-R181 WeakPolarHBondContact O-CB 3.39Å; E178-R181 PolarHBondContact O-N 3.07Å; E178-R181 IonicContact OE1-CZ 3.45Å; E178-R181 IonicContact OE1-NH1 3.1Å; E178-R181 PolarHBondContact OE1-NH1 2.78Å; E178-R181 VanDerWaalsContact OE1-NH1 3.07Å; E178-R181 IonicContact OE2-CZ 3.44Å; E178-R181 IonicContact OE2-NE 2.98Å; E178-R181 IonicContact OE2-NH1 2.8Å; E178-R181 PolarHBondContact OE2-NH1 3.17Å; E178-R181 IonicContact OE2-NH2 3.59Å
179Y97.3Very high97.6Very high19 Ų1959.4 Ų59.48%0.07530%0.297CS..Hα-helixtrans-60.1-44.1-178.9-177.9-88.1000112E175 V177 R181 R182 A194 E197 L198 L201E175-Y179 WeakPolarHBondContact O-CB 3.48Å; E175-Y179 PolarHBondContact O-N 3.44Å; V177-Y179 PolarHBondContact O-N 3.18Å; Y179-R181 VanDerWaalsContact C-N 3.31Å; Y179-R181 PolarHBondContact O-N 2.86Å; Y179-R182 VanDerWaalsContact CE2-CZ 3.47Å; Y179-R182 VanDerWaalsContact O-CD 3.23Å; Y179-R182 WeakPolarHBondContact O-CD 3.19Å; Y179-R182 WeakPolarHBondContact O-CG 3.25Å; Y179-R182 PolarHBondContact OH-NH2 3.21Å; Y179-A194 HydrophobicContact CE1-CB 4.05Å; Y179-A194 WeakPolarHBondContact CE1-O 3.13Å; Y179-A194 VanDerWaalsContact CZ-O 3.28Å; Y179-A194 WeakPolarHBondContact OH-CA 3.48Å; Y179-A194 PolarHBondContact OH-O 3.14Å; Y179-E197 HydrophobicContact CE2-CB 3.7Å; Y179-E197 WeakPolarHBondContact CE2-OE2 3.13Å; Y179-E197 WeakPolarHBondContact OH-CB 3.42Å; Y179-E197 PolarHBondContact OH-OE2 3.26Å; Y179-L198 HydrophobicContact CD1-CB 4.15Å; Y179-L198 HydrophobicContact CD2-CB 4.43Å; Y179-L198 HydrophobicContact CE1-CB 4.28Å; Y179-L198 HydrophobicContact CG-CB 4.22Å; Y179-L198 HydrophobicContact CG-CD1 4.2Å; Y179-L201 HydrophobicContact CD2-CD1 4.24Å
180F97.8Very high97.6Very high1 Ų160.8 Ų60.80%0.00430%0.304CS..Hα-helixtrans-81.7-1-176.6-82.8-84.1000114.5T176 V177 E178 R182 W183 L198 L460 L463 Y464T176-F180 HydrophobicContact CG2-CD2 3.96Å; T176-F180 HydrophobicContact CG2-CE2 4.35Å; T176-F180 WeakPolarHBondContact O-CB 3.38Å; T176-F180 WeakPolarHBondContact O-CD2 3.48Å; T176-F180 PolarHBondContact O-N 3.05Å; V177-F180 PolarHBondContact O-N 2.72Å; E178-F180 VanDerWaalsContact C-N 3.34Å; E178-F180 PolarHBondContact O-N 3.24Å; F180-R182 PolarHBondContact O-N 2.83Å; F180-W183 HydrophobicContact CD1-CB 4.35Å; F180-W183 AromaticContact CD1-CD2 3.51Å; F180-W183 HydrophobicContact CD1-CD2 3.51Å; F180-W183 AromaticContact CD1-CE2 3.83Å; F180-W183 AromaticContact CD1-CE3 3.85Å; F180-W183 HydrophobicContact CD1-CE3 3.85Å; F180-W183 AromaticContact CD1-CG 3.73Å; F180-W183 HydrophobicContact CD1-CG 3.73Å; F180-W183 HydrophobicContact CD1-CZ2 4.45Å; F180-W183 HydrophobicContact CD1-CZ3 4.45Å; F180-W183 AromaticContact CE1-CD2 3.55Å; F180-W183 HydrophobicContact CE1-CD2 3.55Å; F180-W183 AromaticContact CE1-CE2 3.46Å; F180-W183 VanDerWaalsContact CE1-CE2 3.46Å; F180-W183 AromaticContact CE1-CE3 3.73Å; F180-W183 HydrophobicContact CE1-CE3 3.73Å; F180-W183 HydrophobicContact CE1-CG 4.21Å; F180-W183 AromaticContact CE1-CH2 3.86Å; F180-W183 HydrophobicContact CE1-CH2 3.86Å; F180-W183 AromaticContact CE1-CZ2 3.65Å; F180-W183 HydrophobicContact CE1-CZ2 3.65Å; F180-W183 AromaticContact CE1-CZ3 3.88Å; F180-W183 HydrophobicContact CE1-CZ3 3.88Å; F180-W183 AromaticContact CE1-NE1 3.98Å; F180-W183 HydrophobicContact CZ-CZ2 4.44Å; F180-W183 WeakPolarHBondContact O-CB 3.2Å; F180-W183 PolarHBondContact O-N 2.96Å; F180-L198 HydrophobicContact CD2-CD2 4.22Å; F180-L198 HydrophobicContact CE2-CD2 3.68Å; F180-L460 HydrophobicContact CD1-CD2 3.9Å; F180-L460 HydrophobicContact CD2-CD2 3.6Å; F180-L460 HydrophobicContact CE1-CD2 3.85Å; F180-L460 HydrophobicContact CE2-CD1 4.3Å; F180-L460 HydrophobicContact CE2-CD2 3.57Å; F180-L460 HydrophobicContact CE2-CG 4.37Å; F180-L460 HydrophobicContact CG-CD2 3.78Å; F180-L460 HydrophobicContact CZ-CD1 4.19Å; F180-L460 HydrophobicContact CZ-CD2 3.7Å; F180-L463 HydrophobicContact CB-CD1 4.23Å; F180-Y464 HydrophobicContact CB-CE2 4.1Å; F180-Y464 HydrophobicContact CD1-CE2 4.03Å; F180-Y464 HydrophobicContact CG-CE2 4.39Å; F180-Y464 PolarHBondContact O-OH 3.11Å
181R96.4Very high97.7Very high154 Ų15455.8 Ų55.858%0.58128%0.283SS*.G310 helixtrans-58.3-36.1167.3-75.4176.4-177.31647.4112.1V177 E178 Y179 W183 G184V177-R181 WeakPolarHBondContact O-CG 3.29Å; V177-R181 PolarHBondContact O-N 3.14Å; E178-R181 WeakPolarHBondContact O-CB 3.39Å; E178-R181 PolarHBondContact O-N 3.07Å; E178-R181 IonicContact OE1-CZ 3.45Å; E178-R181 IonicContact OE1-NH1 3.1Å; E178-R181 PolarHBondContact OE1-NH1 2.78Å; E178-R181 VanDerWaalsContact OE1-NH1 3.07Å; E178-R181 IonicContact OE2-CZ 3.44Å; E178-R181 IonicContact OE2-NE 2.98Å; E178-R181 IonicContact OE2-NH1 2.8Å; E178-R181 PolarHBondContact OE2-NH1 3.17Å; E178-R181 IonicContact OE2-NH2 3.59Å; Y179-R181 VanDerWaalsContact C-N 3.31Å; Y179-R181 PolarHBondContact O-N 2.86Å; R181-W183 PolarHBondContact O-N 2.81Å; R181-W183 VanDerWaalsContact O-N 3.15Å; R181-G184 PolarHBondContact O-N 3.45Å; R181-G184 VanDerWaalsContact O-N 3.14Å
182R96.2Very high97.8Very high141 Ų14154.9 Ų54.953%0.53228%0.276SS..G310 helixtrans-66.7-13.1-179.880.9-160.9-170.6149.722.5113.9Y179 F180 E197Y179-R182 VanDerWaalsContact CE2-CZ 3.47Å; Y179-R182 VanDerWaalsContact O-CD 3.23Å; Y179-R182 WeakPolarHBondContact O-CD 3.19Å; Y179-R182 WeakPolarHBondContact O-CG 3.25Å; Y179-R182 PolarHBondContact OH-NH2 3.21Å; F180-R182 PolarHBondContact O-N 2.83Å; R182-E197 IonicContact CZ-OE2 3.7Å; R182-E197 VanDerWaalsContact CZ-OE2 3.27Å; R182-E197 IonicContact NH1-OE2 2.93Å; R182-E197 PolarHBondContact NH1-OE2 2.62Å; R182-E197 IonicContact NH2-OE2 3.65Å; R182-E197 PolarHBondContact NH2-OE2 3.35Å
183W97.4Very high97.7Very high11 Ų1160.3 Ų60.34%0.04230%0.302CS..G310 helixtrans-80.7-15.8176-8037000112.3F180 R181 R189 L191 A194 F466 I490 Y492F180-W183 HydrophobicContact CD1-CB 4.35Å; F180-W183 AromaticContact CD1-CD2 3.51Å; F180-W183 HydrophobicContact CD1-CD2 3.51Å; F180-W183 AromaticContact CD1-CE2 3.83Å; F180-W183 AromaticContact CD1-CE3 3.85Å; F180-W183 HydrophobicContact CD1-CE3 3.85Å; F180-W183 AromaticContact CD1-CG 3.73Å; F180-W183 HydrophobicContact CD1-CG 3.73Å; F180-W183 HydrophobicContact CD1-CZ2 4.45Å; F180-W183 HydrophobicContact CD1-CZ3 4.45Å; F180-W183 AromaticContact CE1-CD2 3.55Å; F180-W183 HydrophobicContact CE1-CD2 3.55Å; F180-W183 AromaticContact CE1-CE2 3.46Å; F180-W183 VanDerWaalsContact CE1-CE2 3.46Å; F180-W183 AromaticContact CE1-CE3 3.73Å; F180-W183 HydrophobicContact CE1-CE3 3.73Å; F180-W183 HydrophobicContact CE1-CG 4.21Å; F180-W183 AromaticContact CE1-CH2 3.86Å; F180-W183 HydrophobicContact CE1-CH2 3.86Å; F180-W183 AromaticContact CE1-CZ2 3.65Å; F180-W183 HydrophobicContact CE1-CZ2 3.65Å; F180-W183 AromaticContact CE1-CZ3 3.88Å; F180-W183 HydrophobicContact CE1-CZ3 3.88Å; F180-W183 AromaticContact CE1-NE1 3.98Å; F180-W183 HydrophobicContact CZ-CZ2 4.44Å; F180-W183 WeakPolarHBondContact O-CB 3.2Å; F180-W183 PolarHBondContact O-N 2.96Å; R181-W183 PolarHBondContact O-N 2.81Å; R181-W183 VanDerWaalsContact O-N 3.15Å; W183-R189 HydrophobicContact CD2-CB 4.49Å; W183-R189 HydrophobicContact CD2-CG 4.37Å; W183-R189 HydrophobicContact CH2-CB 3.81Å; W183-R189 HydrophobicContact CZ2-CB 3.62Å; W183-R189 HydrophobicContact CZ2-CG 4.32Å; W183-R189 HydrophobicContact CZ3-CB 4.32Å; W183-L191 HydrophobicContact CH2-CD1 3.96Å; W183-A194 HydrophobicContact CH2-CB 4.44Å; W183-A194 HydrophobicContact CZ2-CB 3.48Å; W183-A194 VanDerWaalsContact CZ2-CB 3.48Å; W183-F466 HydrophobicContact CZ3-CE1 4.16Å; W183-I490 HydrophobicContact CH2-CG2 4.22Å; W183-I490 HydrophobicContact CZ3-CG2 4.31Å; W183-Y492 HydrophobicContact CB-CE2 3.73Å; W183-Y492 HydrophobicContact CD2-CD1 4.43Å; W183-Y492 AromaticContact CD2-CE1 4Å; W183-Y492 HydrophobicContact CD2-CE1 4Å; W183-Y492 HydrophobicContact CD2-CE2 4.36Å; W183-Y492 AromaticContact CD2-CZ 3.96Å; W183-Y492 AromaticContact CE3-CD1 3.37Å; W183-Y492 HydrophobicContact CE3-CD1 3.37Å; W183-Y492 AromaticContact CE3-CD2 3.81Å; W183-Y492 HydrophobicContact CE3-CD2 3.81Å; W183-Y492 AromaticContact CE3-CE1 3.34Å; W183-Y492 HydrophobicContact CE3-CE1 3.34Å; W183-Y492 AromaticContact CE3-CE2 3.79Å; W183-Y492 HydrophobicContact CE3-CE2 3.79Å; W183-Y492 AromaticContact CE3-CG 3.61Å; W183-Y492 HydrophobicContact CE3-CG 3.61Å; W183-Y492 AromaticContact CE3-CZ 3.56Å; W183-Y492 HydrophobicContact CG-CE2 4.41Å; W183-Y492 HydrophobicContact CH2-CD1 4.46Å; W183-Y492 AromaticContact CZ3-CD1 3.39Å; W183-Y492 HydrophobicContact CZ3-CD1 3.39Å; W183-Y492 HydrophobicContact CZ3-CD2 4.46Å; W183-Y492 AromaticContact CZ3-CE1 3.71Å; W183-Y492 HydrophobicContact CZ3-CE1 3.71Å; W183-Y492 AromaticContact CZ3-CG 3.81Å; W183-Y492 HydrophobicContact CZ3-CG 3.81Å; W183-Y492 VanDerWaalsContact O-CE2 3.26Å; W183-Y492 WeakPolarHBondContact O-CE2 3.33Å; W183-Y492 VanDerWaalsContact O-CZ 3.31Å; W183-Y492 PolarHBondContact O-OH 3.45Å
184G97.2Very high97.6Very high30 Ų3059.1 Ų59.131%0.30930%0.297SS..  trans66.7-141.9178.800000112.9R181 Y464 R494R181-G184 PolarHBondContact O-N 3.45Å; R181-G184 VanDerWaalsContact O-N 3.14Å; G184-Y464 PolarHBondContact O-OH 2.85Å; G184-R494 PolarHBondContact O-NH2 2.9Å
185D97.6Very high97.7Very high106 Ų10655.4 Ų55.457%0.56727%0.271SS*.SBendtrans-100.6-26.9-173.4-68.3-23.1000114.3K493 R494D185-K493 CarbonylContact O-C 3.43Å; D185-K493 WeakPolarHBondContact O-CA 3.44Å; D185-R494 HydrophobicContact CB-CB 4.49Å; D185-R494 PolarHBondContact O-N 2.75Å; D185-R494 IonicContact OD1-CZ 3.44Å; D185-R494 IonicContact OD1-NE 2.77Å; D185-R494 PolarHBondContact OD1-NE 2.72Å; D185-R494 IonicContact OD1-NH2 3.13Å; D185-R494 PolarHBondContact OD1-NH2 3.47Å
186S98.3Very high97.5Very high83 Ų8355 Ų5558%0.5827%0.271SS*.EExtended strand (participates in β ladder)trans-163.216117560.80000110.7Y492S186-Y492 CarbonylContact C-O 3.59Å; S186-Y492 WeakPolarHBondContact CA-O 3.34Å; S186-Y492 WeakPolarHBondContact CB-O 3.47Å
187G98.3Very high97.3Very high25 Ų2559.1 Ų59.126%0.25829%0.291SS..EExtended strand (participates in β ladder)trans164.3-170.1174.300000113.3R491 Y492G187-R491 WeakPolarHBondContact O-CA 3.46Å; G187-Y492 PolarHBondContact N-O 3.15Å; G187-Y492 WeakPolarHBondContact O-CD1 3.48Å; G187-Y492 WeakPolarHBondContact O-CE1 3.17Å; G187-Y492 PolarHBondContact O-N 3.4Å
188E98.6Very high97.2Very high85 Ų8556.8 Ų56.840%0.39728%0.276SS..EExtended strand (participates in β ladder)trans-125.9123.5173.1-63.6-174.8177.300108.6V469 I489 I490 R491E188-V469 HydrophobicContact CG-CG2 4.06Å; E188-I489 HydrophobicContact CB-CG2 3.93Å; E188-I490 WeakPolarHBondContact CA-O 3.45Å; E188-R491 HydrophobicContact CG-CB 4.04Å; E188-R491 HydrophobicContact CG-CG 4.18Å; E188-R491 IonicContact OE1-CZ 3.8Å; E188-R491 VanDerWaalsContact OE1-CZ 3.27Å; E188-R491 IonicContact OE1-NE 3.62Å; E188-R491 PolarHBondContact OE1-NE 3.29Å; E188-R491 IonicContact OE1-NH2 3.27Å; E188-R491 PolarHBondContact OE1-NH2 3.43Å
189R98.3Very high97.1Very high140 Ų14052 Ų5253%0.52825%0.254SS..EExtended strand (participates in β ladder)trans-144157.1-174.3-67-67.2-175-1492110.7W183 L191 I489 I490 Y492W183-R189 HydrophobicContact CD2-CB 4.49Å; W183-R189 HydrophobicContact CD2-CG 4.37Å; W183-R189 HydrophobicContact CH2-CB 3.81Å; W183-R189 HydrophobicContact CZ2-CB 3.62Å; W183-R189 HydrophobicContact CZ2-CG 4.32Å; W183-R189 HydrophobicContact CZ3-CB 4.32Å; R189-L191 PolarHBondContact O-N 2.87Å; R189-I489 WeakPolarHBondContact O-CA 3.21Å; R189-I490 PolarHBondContact N-O 3.21Å; R189-I490 VanDerWaalsContact N-O 3.11Å; R189-I490 PolarHBondContact O-N 3.38Å; R189-Y492 HydrophobicContact CB-CE1 4.19Å; R189-Y492 HydrophobicContact CG-CE1 3.73Å
190N98.5Very high96.9Very high30 Ų3052 Ų5216%0.1626%0.256CS..EExtended strand (participates in β ladder)trans-70.7107.4172.4-172.1-36.6000110F192 E193 A194 P488 I489N190-F192 PolarHBondContact OD1-N 3.21Å; N190-F192 VanDerWaalsContact OD1-N 3.08Å; N190-E193 HydrophobicContact CB-CB 4.1Å; N190-E193 HydrophobicContact CB-CG 4.3Å; N190-E193 WeakPolarHBondContact CB-OE2 3.3Å; N190-E193 VanDerWaalsContact CG-CD 3.42Å; N190-E193 WeakPolarHBondContact ND2-CG 3.43Å; N190-E193 PolarHBondContact ND2-OE1 3.09Å; N190-E193 PolarHBondContact ND2-OE2 2.83Å; N190-E193 PolarHBondContact OD1-N 2.97Å; N190-A194 VanDerWaalsContact O-CB 3.3Å; N190-A194 WeakPolarHBondContact O-CB 3.4Å; N190-A194 PolarHBondContact O-N 3.15Å; N190-P488 CarbonylContact C-O 3.54Å; N190-P488 WeakPolarHBondContact CA-O 3.44Å; N190-P488 WeakPolarHBondContact OD1-CG 3.29Å; N190-I489 HydrophobicContact CB-CD1 3.83Å
191L98.4Very high96.7Very high0 Ų053.7 Ų53.70%026%0.264CS..Hα-helixtrans-71.8-36.6-178-177.461.8000111.9W183 R189 A194 L195 F322 W457 P488 I490W183-L191 HydrophobicContact CH2-CD1 3.96Å; R189-L191 PolarHBondContact O-N 2.87Å; L191-A194 PolarHBondContact O-N 3.46Å; L191-L195 HydrophobicContact CD1-CD1 3.79Å; L191-L195 HydrophobicContact CD1-CG 3.99Å; L191-L195 HydrophobicContact CD2-CD1 4.21Å; L191-L195 HydrophobicContact CG-CD1 3.65Å; L191-L195 HydrophobicContact CG-CG 4.26Å; L191-L195 WeakPolarHBondContact O-CB 3.39Å; L191-L195 VanDerWaalsContact O-CG 3.28Å; L191-L195 WeakPolarHBondContact O-CG 3.26Å; L191-L195 PolarHBondContact O-N 3.37Å; L191-F322 HydrophobicContact CB-CE2 4.47Å; L191-F322 HydrophobicContact CB-CZ 4.47Å; L191-F322 HydrophobicContact CD2-CE2 4.39Å; L191-W457 HydrophobicContact CD2-CH2 4.17Å; L191-W457 HydrophobicContact CD2-CZ2 4.24Å; L191-P488 PolarHBondContact N-O 2.85Å; L191-I490 HydrophobicContact CB-CB 4.18Å; L191-I490 HydrophobicContact CB-CG2 3.73Å; L191-I490 HydrophobicContact CD1-CG2 4.32Å; L191-I490 HydrophobicContact CD2-CB 4.48Å; L191-I490 HydrophobicContact CD2-CD1 3.66Å; L191-I490 HydrophobicContact CD2-CG2 4.23Å; L191-I490 HydrophobicContact CG-CG2 4.29Å
192F97.8Very high96.7Very high38 Ų3846.3 Ų46.317%0.16724%0.236CC..Hα-helixtrans-67.7-48.4-178.1174.8-119.8000111.4N190 A194 L195 S196 T315 A318 T484 P485 P488N190-F192 PolarHBondContact OD1-N 3.21Å; N190-F192 VanDerWaalsContact OD1-N 3.08Å; F192-A194 VanDerWaalsContact C-N 3.26Å; F192-A194 PolarHBondContact O-N 3Å; F192-L195 PolarHBondContact O-N 3.02Å; F192-S196 WeakPolarHBondContact O-CB 3.34Å; F192-S196 PolarHBondContact O-N 3.07Å; F192-S196 PolarHBondContact O-OG 3.36Å; F192-S196 VanDerWaalsContact O-OG 3.13Å; F192-T315 HydrophobicContact CD2-CG2 4.4Å; F192-T315 HydrophobicContact CE2-CG2 3.48Å; F192-T315 VanDerWaalsContact CE2-CG2 3.48Å; F192-T315 HydrophobicContact CZ-CG2 3.94Å; F192-A318 HydrophobicContact CB-CB 4.03Å; F192-A318 HydrophobicContact CD2-CB 3.95Å; F192-A318 HydrophobicContact CG-CB 4.45Å; F192-T484 HydrophobicContact CE1-CG2 3.78Å; F192-T484 HydrophobicContact CE2-CG2 4.29Å; F192-T484 HydrophobicContact CZ-CG2 3.54Å; F192-P485 HydrophobicContact CB-CG 4.09Å; F192-P485 HydrophobicContact CG-CG 4.26Å; F192-P488 HydrophobicContact CB-CB 3.84Å; F192-P488 HydrophobicContact CB-CG 3.59Å
193E95.6Very high96.5Very high114 Ų11439.6 Ų39.653%0.53321%0.211SC..Hα-helixtrans-57.1-43.6173.8-75.8169.8-17100110.8N190 L195 S196 E197N190-E193 HydrophobicContact CB-CB 4.1Å; N190-E193 HydrophobicContact CB-CG 4.3Å; N190-E193 WeakPolarHBondContact CB-OE2 3.3Å; N190-E193 VanDerWaalsContact CG-CD 3.42Å; N190-E193 WeakPolarHBondContact ND2-CG 3.43Å; N190-E193 PolarHBondContact ND2-OE1 3.09Å; N190-E193 PolarHBondContact ND2-OE2 2.83Å; N190-E193 PolarHBondContact OD1-N 2.97Å; E193-L195 PolarHBondContact O-N 2.77Å; E193-S196 PolarHBondContact O-N 3.32Å; E193-E197 WeakPolarHBondContact O-CG 3.36Å; E193-E197 PolarHBondContact O-N 3.23Å
194A97.3Very high96.3Very high3 Ų339.1 Ų39.13%0.02521%0.209CC..Hα-helixtrans-64.2-43.4-179.400000113.2Y179 W183 N190 L191 F192 E197 L198Y179-A194 HydrophobicContact CE1-CB 4.05Å; Y179-A194 WeakPolarHBondContact CE1-O 3.13Å; Y179-A194 VanDerWaalsContact CZ-O 3.28Å; Y179-A194 WeakPolarHBondContact OH-CA 3.48Å; Y179-A194 PolarHBondContact OH-O 3.14Å; W183-A194 HydrophobicContact CH2-CB 4.44Å; W183-A194 HydrophobicContact CZ2-CB 3.48Å; W183-A194 VanDerWaalsContact CZ2-CB 3.48Å; N190-A194 VanDerWaalsContact O-CB 3.3Å; N190-A194 WeakPolarHBondContact O-CB 3.4Å; N190-A194 PolarHBondContact O-N 3.15Å; L191-A194 PolarHBondContact O-N 3.46Å; F192-A194 VanDerWaalsContact C-N 3.26Å; F192-A194 PolarHBondContact O-N 3Å; A194-E197 PolarHBondContact O-N 3.35Å; A194-L198 WeakPolarHBondContact O-CB 3.12Å; A194-L198 PolarHBondContact O-N 3.12Å
195L98.1Very high96Very high0 Ų038.3 Ų38.30%020%0.199CC..Hα-helixtrans-70.8-34176.9-71.6168.6000111.9L191 F192 E193 L198 I199 A318 I456 W457 L460L191-L195 HydrophobicContact CD1-CD1 3.79Å; L191-L195 HydrophobicContact CD1-CG 3.99Å; L191-L195 HydrophobicContact CD2-CD1 4.21Å; L191-L195 HydrophobicContact CG-CD1 3.65Å; L191-L195 HydrophobicContact CG-CG 4.26Å; L191-L195 WeakPolarHBondContact O-CB 3.39Å; L191-L195 VanDerWaalsContact O-CG 3.28Å; L191-L195 WeakPolarHBondContact O-CG 3.26Å; L191-L195 PolarHBondContact O-N 3.37Å; F192-L195 PolarHBondContact O-N 3.02Å; E193-L195 PolarHBondContact O-N 2.77Å; L195-L198 PolarHBondContact O-N 3.29Å; L195-I199 HydrophobicContact CB-CD1 4.35Å; L195-I199 WeakPolarHBondContact O-CB 3.27Å; L195-I199 WeakPolarHBondContact O-CD1 3.45Å; L195-I199 WeakPolarHBondContact O-CG1 3.11Å; L195-I199 PolarHBondContact O-N 3.05Å; L195-A318 HydrophobicContact CD1-CB 4.08Å; L195-I456 HydrophobicContact CD2-CG2 3.88Å; L195-W457 HydrophobicContact CD1-CZ2 4.34Å; L195-L460 HydrophobicContact CD2-CD1 4.17Å
196S94.6Very high95.8Very high24 Ų2433.5 Ų33.517%0.16817%0.173CC..Hα-helixtrans-61.4-50.6171.4-68.40000110.8F192 E193 L198 I199 I200 Q310F192-S196 WeakPolarHBondContact O-CB 3.34Å; F192-S196 PolarHBondContact O-N 3.07Å; F192-S196 PolarHBondContact O-OG 3.36Å; F192-S196 VanDerWaalsContact O-OG 3.13Å; E193-S196 PolarHBondContact O-N 3.32Å; S196-L198 PolarHBondContact O-N 3.17Å; S196-I199 PolarHBondContact O-N 2.92Å; S196-I200 PolarHBondContact O-N 3.35Å; S196-Q310 PolarHBondContact O-NE2 3.49Å
197E93.7Very high95.4Very high87 Ų8729.6 Ų29.641%0.40715%0.146SC..Hα-helixtrans-60.9-41.4176.3-73.3175-161.600112.7Y179 R182 E193 A194 I200 L201Y179-E197 HydrophobicContact CE2-CB 3.7Å; Y179-E197 WeakPolarHBondContact CE2-OE2 3.13Å; Y179-E197 WeakPolarHBondContact OH-CB 3.42Å; Y179-E197 PolarHBondContact OH-OE2 3.26Å; R182-E197 IonicContact CZ-OE2 3.7Å; R182-E197 VanDerWaalsContact CZ-OE2 3.27Å; R182-E197 IonicContact NH1-OE2 2.93Å; R182-E197 PolarHBondContact NH1-OE2 2.62Å; R182-E197 IonicContact NH2-OE2 3.65Å; R182-E197 PolarHBondContact NH2-OE2 3.35Å; E193-E197 WeakPolarHBondContact O-CG 3.36Å; E193-E197 PolarHBondContact O-N 3.23Å; A194-E197 PolarHBondContact O-N 3.35Å; E197-I200 WeakPolarHBondContact O-CG2 3.23Å; E197-L201 WeakPolarHBondContact O-CG 3.34Å
198L96.2Very high94.9Very high0 Ų028.4 Ų28.40%013%0.134CC..Hα-helixtrans-66.8-42.6177.2172.661.8000112.1E175 T176 Y179 F180 A194 L195 S196 I200 L201 T202 I456E175-L198 HydrophobicContact CB-CD1 4.2Å; T176-L198 HydrophobicContact CG2-CD2 3.84Å; Y179-L198 HydrophobicContact CD1-CB 4.15Å; Y179-L198 HydrophobicContact CD2-CB 4.43Å; Y179-L198 HydrophobicContact CE1-CB 4.28Å; Y179-L198 HydrophobicContact CG-CB 4.22Å; Y179-L198 HydrophobicContact CG-CD1 4.2Å; F180-L198 HydrophobicContact CD2-CD2 4.22Å; F180-L198 HydrophobicContact CE2-CD2 3.68Å; A194-L198 WeakPolarHBondContact O-CB 3.12Å; A194-L198 PolarHBondContact O-N 3.12Å; L195-L198 PolarHBondContact O-N 3.29Å; S196-L198 PolarHBondContact O-N 3.17Å; L198-I200 VanDerWaalsContact C-N 3.28Å; L198-I200 PolarHBondContact O-N 3.31Å; L198-L201 WeakPolarHBondContact O-CB 3.46Å; L198-L201 PolarHBondContact O-N 3.39Å; L198-T202 HydrophobicContact CD1-CG2 3.7Å; L198-T202 HydrophobicContact CG-CG2 4.09Å; L198-T202 WeakPolarHBondContact O-CG2 3.07Å; L198-T202 PolarHBondContact O-N 2.84Å; L198-T202 PolarHBondContact O-OG1 3.47Å; L198-I456 HydrophobicContact CD2-CD1 4.26Å; L198-I456 HydrophobicContact CD2-CG1 4.21Å; L198-I456 HydrophobicContact CD2-CG2 4.06Å
199I96.3Very high94.2Very high0 Ų024.7 Ų24.70%012%0.118CC..Hα-helixtrans-69.7-29.4-173-72.6166.1000111.2L195 S196 L201 T202 A203 I456L195-I199 HydrophobicContact CB-CD1 4.35Å; L195-I199 WeakPolarHBondContact O-CB 3.27Å; L195-I199 WeakPolarHBondContact O-CD1 3.45Å; L195-I199 WeakPolarHBondContact O-CG1 3.11Å; L195-I199 PolarHBondContact O-N 3.05Å; S196-I199 PolarHBondContact O-N 2.92Å; I199-L201 VanDerWaalsContact C-N 3.3Å; I199-L201 PolarHBondContact O-N 2.82Å; I199-T202 WeakPolarHBondContact CA-OG1 3.44Å; I199-T202 PolarHBondContact O-N 3.3Å; I199-T202 PolarHBondContact O-OG1 3.41Å; I199-A203 WeakPolarHBondContact O-CB 3.43Å; I199-A203 PolarHBondContact O-N 2.99Å; I199-I456 HydrophobicContact CD1-CD1 4.16Å; I199-I456 HydrophobicContact CG1-CD1 3.62Å
200I92.7Very high93.5Very high21 Ų2125.7 Ų25.711%0.10813%0.126CC..Hα-helixtrans-68.8-36.7176.3-170.8171.2000110.2S196 E197 L198 S204 L216 Y224 L306S196-I200 PolarHBondContact O-N 3.35Å; E197-I200 WeakPolarHBondContact O-CG2 3.23Å; L198-I200 VanDerWaalsContact C-N 3.28Å; L198-I200 PolarHBondContact O-N 3.31Å; I200-S204 WeakPolarHBondContact O-CB 3.32Å; I200-S204 PolarHBondContact O-N 3.15Å; I200-L216 HydrophobicContact CG1-CD1 4.4Å; I200-Y224 HydrophobicContact CD1-CD2 3.75Å; I200-Y224 HydrophobicContact CD1-CE2 4.46Å; I200-Y224 HydrophobicContact CD1-CG 4.1Å; I200-L306 HydrophobicContact CD1-CD2 4.46Å; I200-L306 HydrophobicContact CG1-CD1 4.29Å; I200-L306 HydrophobicContact CG1-CD2 4.14Å
201L93.5Very high92.9Very high35 Ų3526.9 Ų26.918%0.18313%0.131CC..Hα-helixtrans-67-53.3175-56.6176.7000110.5Y179 E197 L198 I199 A203 S204 S205 L216Y179-L201 HydrophobicContact CD2-CD1 4.24Å; E197-L201 WeakPolarHBondContact O-CG 3.34Å; L198-L201 WeakPolarHBondContact O-CB 3.46Å; L198-L201 PolarHBondContact O-N 3.39Å; I199-L201 VanDerWaalsContact C-N 3.3Å; I199-L201 PolarHBondContact O-N 2.82Å; L201-A203 PolarHBondContact O-N 3.23Å; L201-S204 PolarHBondContact O-N 3Å; L201-S205 WeakPolarHBondContact O-CB 3.13Å; L201-S205 PolarHBondContact O-N 3.41Å; L201-S205 PolarHBondContact O-OG 3.17Å; L201-S205 VanDerWaalsContact O-OG 3.05Å; L201-L216 HydrophobicContact CD2-CB 4.45Å; L201-L216 HydrophobicContact CD2-CD1 4.41Å
202T95.5Very high92.4Very high0 Ų027.1 Ų27.10%013%0.132CC..Hα-helixtrans-64.2-42.4-178.159.50000112.4I172 E175 L198 I199 S204 S205 C206 Q452I172-T202 HydrophobicContact CB-CG2 4.39Å; I172-T202 HydrophobicContact CG1-CG2 4.37Å; I172-T202 HydrophobicContact CG2-CG2 4.07Å; E175-T202 HydrophobicContact CB-CG2 3.75Å; E175-T202 HydrophobicContact CG-CG2 4.4Å; L198-T202 HydrophobicContact CD1-CG2 3.7Å; L198-T202 HydrophobicContact CG-CG2 4.09Å; L198-T202 WeakPolarHBondContact O-CG2 3.07Å; L198-T202 PolarHBondContact O-N 2.84Å; L198-T202 PolarHBondContact O-OG1 3.47Å; I199-T202 WeakPolarHBondContact CA-OG1 3.44Å; I199-T202 PolarHBondContact O-N 3.3Å; I199-T202 PolarHBondContact O-OG1 3.41Å; T202-S204 VanDerWaalsContact C-N 3.35Å; T202-S204 PolarHBondContact O-N 3.34Å; T202-S205 PolarHBondContact O-N 2.67Å; T202-C206 WeakPolarHBondContact O-CB 3.45Å; T202-C206 PolarHBondContact O-N 2.9Å; T202-C206 PolarHBondContact O-SG 2.87Å; T202-Q452 PolarHBondContact OG1-NE2 2.81Å
203A93.6Very high91.9Very high0 Ų027.9 Ų27.90%013%0.134CC..Hα-helixtrans-63.7-41.6177.200000111I199 L201 C206 L207 L306I199-A203 WeakPolarHBondContact O-CB 3.43Å; I199-A203 PolarHBondContact O-N 2.99Å; L201-A203 PolarHBondContact O-N 3.23Å; A203-C206 PolarHBondContact O-N 3.47Å; A203-L207 HydrophobicContact CB-CD1 4.42Å; A203-L207 WeakPolarHBondContact O-CA 3.32Å; A203-L207 WeakPolarHBondContact O-CB 3.46Å; A203-L207 VanDerWaalsContact O-CG 3.27Å; A203-L207 WeakPolarHBondContact O-CG 3.44Å; A203-L207 PolarHBondContact O-N 3.35Å; A203-L306 HydrophobicContact CB-CD1 3.67Å
204S92.2Very high91.6Very high0 Ų026.9 Ų26.90%014%0.14CC..Hα-helixtrans-67.7-43.7176.2-172.30000112.3I200 L201 T202 C206 L207 H208 G209 L216I200-S204 WeakPolarHBondContact O-CB 3.32Å; I200-S204 PolarHBondContact O-N 3.15Å; L201-S204 PolarHBondContact O-N 3Å; T202-S204 VanDerWaalsContact C-N 3.35Å; T202-S204 PolarHBondContact O-N 3.34Å; S204-C206 VanDerWaalsContact C-N 3.25Å; S204-C206 PolarHBondContact O-N 2.95Å; S204-L207 PolarHBondContact O-N 2.88Å; S204-H208 WeakPolarHBondContact O-CA 3.42Å; S204-H208 WeakPolarHBondContact O-CB 3.44Å; S204-H208 PolarHBondContact O-N 3.49Å; S204-H208 PolarHBondContact OG-ND1 3.46Å; S204-G209 PolarHBondContact O-N 3.26Å; S204-L216 VanDerWaalsContact OG-CD1 3.3Å; S204-L216 WeakPolarHBondContact OG-CD1 3.47Å
205S91.4Very high91.1Very high13 Ų1330.1 Ų30.19%0.09116%0.155CC..Hα-helixtrans-55.3-41.1175.7-66.70000112.2E175 L201 T202 R213E175-S205 PolarHBondContact OE1-OG 2.97Å; L201-S205 WeakPolarHBondContact O-CB 3.13Å; L201-S205 PolarHBondContact O-N 3.41Å; L201-S205 PolarHBondContact O-OG 3.17Å; L201-S205 VanDerWaalsContact O-OG 3.05Å; T202-S205 PolarHBondContact O-N 2.67Å; S205-R213 WeakPolarHBondContact OG-CD 3.37Å; S205-R213 WeakPolarHBondContact OG-CG 3.48Å; S205-R213 PolarHBondContact OG-NE 3.23Å
206C92.1Very high90.4Very high5 Ų531.2 Ų31.23%0.03416%0.16CC..Hα-helixtrans-83.8-41-179.3-63.50000113.7H168 T202 A203 S204 F448H168-C206 HydrophobicContact CB-CB 4.38Å; H168-C206 VanDerWaalsContact CG-SG 3.57Å; H168-C206 PolarHBondContact NE2-O 3.39Å; T202-C206 WeakPolarHBondContact O-CB 3.45Å; T202-C206 PolarHBondContact O-N 2.9Å; T202-C206 PolarHBondContact O-SG 2.87Å; A203-C206 PolarHBondContact O-N 3.47Å; S204-C206 VanDerWaalsContact C-N 3.25Å; S204-C206 PolarHBondContact O-N 2.95Å; C206-F448 HydrophobicContact CB-CE2 3.68Å; C206-F448 HydrophobicContact CB-CZ 4.09Å
207L90.1Very high89.9Confident2 Ų234 Ų341%0.0117%0.174CC..Hα-helixtrans-103.9-16.5-165.7-55.8178.4000114.1L160 A203 S204 I278 L305 F448L160-L207 HydrophobicContact CD2-CD2 3.87Å; A203-L207 HydrophobicContact CB-CD1 4.42Å; A203-L207 WeakPolarHBondContact O-CA 3.32Å; A203-L207 WeakPolarHBondContact O-CB 3.46Å; A203-L207 VanDerWaalsContact O-CG 3.27Å; A203-L207 WeakPolarHBondContact O-CG 3.44Å; A203-L207 PolarHBondContact O-N 3.35Å; S204-L207 PolarHBondContact O-N 2.88Å; L207-I278 HydrophobicContact CD2-CG1 4.45Å; L207-I278 VanDerWaalsContact O-CB 3.23Å; L207-I278 WeakPolarHBondContact O-CB 3.05Å; L207-I278 VanDerWaalsContact O-CG2 3.24Å; L207-I278 WeakPolarHBondContact O-CG2 3.36Å; L207-L305 HydrophobicContact CB-CD2 3.73Å; L207-L305 HydrophobicContact CB-CG 4.09Å; L207-L305 HydrophobicContact CD1-CD1 4.18Å; L207-L305 HydrophobicContact CD1-CD2 4.3Å; L207-L305 HydrophobicContact CD1-CG 3.82Å; L207-L305 HydrophobicContact CD2-CD2 4.38Å; L207-L305 HydrophobicContact CG-CD2 4.35Å; L207-L305 HydrophobicContact CG-CG 4.41Å; L207-F448 HydrophobicContact CD1-CD1 4.22Å; L207-F448 HydrophobicContact CD1-CE1 3.69Å; L207-F448 HydrophobicContact CD1-CE2 4.43Å; L207-F448 HydrophobicContact CD1-CZ 3.81Å; L207-F448 HydrophobicContact CD2-CD2 3.96Å; L207-F448 HydrophobicContact CD2-CE1 4.38Å; L207-F448 HydrophobicContact CD2-CE2 3.77Å; L207-F448 HydrophobicContact CD2-CG 4.34Å; L207-F448 HydrophobicContact CD2-CZ 3.99Å; L207-F448 HydrophobicContact CG-CE1 4.22Å; L207-F448 HydrophobicContact CG-CE2 4.07Å; L207-F448 HydrophobicContact CG-CZ 3.82Å
208H88.9Confident89.2Confident0 Ų038.4 Ų38.40%019%0.194CC..THydrogen-bonded Turntrans-115.4-18.6-179.8-64.3171.9000113.6S204 I212 F261 L302 L306S204-H208 WeakPolarHBondContact O-CA 3.42Å; S204-H208 WeakPolarHBondContact O-CB 3.44Å; S204-H208 PolarHBondContact O-N 3.49Å; S204-H208 PolarHBondContact OG-ND1 3.46Å; H208-I212 HydrophobicContact CB-CB 3.69Å; H208-I212 HydrophobicContact CB-CD1 3.85Å; H208-I212 HydrophobicContact CB-CG1 4.32Å; H208-I212 HydrophobicContact CB-CG2 3.66Å; H208-F261 AromaticContact CE1-CZ 3.92Å; H208-L302 PolarHBondContact NE2-O 2.6Å; H208-L306 VanDerWaalsContact CE1-CB 3.46Å; H208-L306 WeakPolarHBondContact CE1-CB 3.42Å
209G83.4Confident88.6Confident6 Ų645.6 Ų45.66%0.06223%0.228CC..  trans88.2170-176.200000113.2S204 E211 I212 R213S204-G209 PolarHBondContact O-N 3.26Å; G209-E211 VanDerWaalsContact C-N 3.31Å; G209-E211 PolarHBondContact O-N 3.32Å; G209-I212 PolarHBondContact O-N 2.75Å; G209-R213 WeakPolarHBondContact O-CB 3.47Å; G209-R213 PolarHBondContact O-N 3.16Å; G209-R213 VanDerWaalsContact O-N 3.08Å
210K84Confident88.1Confident162 Ų16246.3 Ų46.370%0.70423%0.232SC*.Hα-helixtrans-65.3-33.2-170.4-68.2-178.9-178.7175.60112.7S214K210-S214 VanDerWaalsContact O-CB 3.28Å; K210-S214 WeakPolarHBondContact O-CB 3.43Å; K210-S214 PolarHBondContact O-N 2.87Å; K210-S214 PolarHBondContact O-OG 2.87Å
211E86.4Confident87.7Confident55 Ų5547.1 Ų47.126%0.25724%0.242SC..Hα-helixtrans-63.6-51-178.6-60.295.6135.200111.1G209 S214 M215 V264 R268G209-E211 VanDerWaalsContact C-N 3.31Å; G209-E211 PolarHBondContact O-N 3.32Å; E211-S214 PolarHBondContact O-N 2.71Å; E211-S214 PolarHBondContact O-OG 3.48Å; E211-M215 WeakPolarHBondContact O-CG 3.23Å; E211-M215 PolarHBondContact O-N 2.76Å; E211-V264 HydrophobicContact CB-CG1 3.94Å; E211-R268 IonicContact OE1-CZ 2.62Å; E211-R268 IonicContact OE1-NE 3.32Å; E211-R268 PolarHBondContact OE1-NE 3.47Å; E211-R268 IonicContact OE1-NH2 3.78Å; E211-R268 PolarHBondContact OE1-NH2 3.44Å; E211-R268 IonicContact OE2-NH2 2.78Å; E211-R268 PolarHBondContact OE2-NH2 3.15Å; E211-R268 VanDerWaalsContact OE2-NH2 3.13Å
212I86.2Confident87.5Confident4 Ų450.1 Ų50.12%0.02126%0.255CS..Hα-helixtrans-68.2-43.4178.5-68172.1000110.2H208 G209 S214 M215 L216 F261 V264 L302H208-I212 HydrophobicContact CB-CB 3.69Å; H208-I212 HydrophobicContact CB-CD1 3.85Å; H208-I212 HydrophobicContact CB-CG1 4.32Å; H208-I212 HydrophobicContact CB-CG2 3.66Å; G209-I212 PolarHBondContact O-N 2.75Å; I212-S214 VanDerWaalsContact C-N 3.26Å; I212-S214 PolarHBondContact O-N 3.36Å; I212-M215 WeakPolarHBondContact O-CB 3.48Å; I212-M215 PolarHBondContact O-N 3.1Å; I212-L216 PolarHBondContact O-N 2.85Å; I212-F261 HydrophobicContact CD1-CD1 3.69Å; I212-F261 HydrophobicContact CD1-CE1 3.73Å; I212-F261 HydrophobicContact CG1-CD1 4.12Å; I212-F261 HydrophobicContact CG1-CE1 4.11Å; I212-F261 HydrophobicContact CG2-CD1 4.46Å; I212-F261 HydrophobicContact CG2-CE1 3.66Å; I212-F261 HydrophobicContact CG2-CZ 4.49Å; I212-V264 HydrophobicContact CD1-CG1 4.4Å; I212-V264 HydrophobicContact CG1-CB 4.34Å; I212-V264 HydrophobicContact CG1-CG1 4.04Å; I212-V264 HydrophobicContact CG1-CG2 4.07Å; I212-L302 HydrophobicContact CD1-CD1 4.13Å
213R89.1Confident87.3Confident54 Ų5451 Ų5120%0.20426%0.26CS..Hα-helixtrans-55.9-40.5176.2169.862.6-177.384.80.5112.6E175 S205 G209 M215 L216E175-R213 VanDerWaalsContact CD-NH2 3.34Å; E175-R213 IonicContact OE1-CZ 3.66Å; E175-R213 VanDerWaalsContact OE1-CZ 3.32Å; E175-R213 IonicContact OE1-NE 2.75Å; E175-R213 PolarHBondContact OE1-NE 2.96Å; E175-R213 IonicContact OE1-NH2 3.44Å; E175-R213 PolarHBondContact OE1-NH2 3.05Å; E175-R213 VanDerWaalsContact OE1-NH2 3.08Å; E175-R213 IonicContact OE2-CZ 3.6Å; E175-R213 IonicContact OE2-NE 2.84Å; E175-R213 IonicContact OE2-NH2 3.66Å; E175-R213 PolarHBondContact OE2-NH2 3.3Å; S205-R213 WeakPolarHBondContact OG-CD 3.37Å; S205-R213 WeakPolarHBondContact OG-CG 3.48Å; S205-R213 PolarHBondContact OG-NE 3.23Å; G209-R213 WeakPolarHBondContact O-CB 3.47Å; G209-R213 PolarHBondContact O-N 3.16Å; G209-R213 VanDerWaalsContact O-N 3.08Å; R213-M215 PolarHBondContact O-N 3.27Å; R213-L216 WeakPolarHBondContact O-CB 3.49Å; R213-L216 PolarHBondContact O-N 3.2Å; R213-L216 VanDerWaalsContact O-N 3.13Å
214S87.8Confident87Confident94 Ų9451.3 Ų51.366%0.65726%0.261SS*.Hα-helixtrans-66.1-22.2179.274.30000113.2K210 E211 I212K210-S214 VanDerWaalsContact O-CB 3.28Å; K210-S214 WeakPolarHBondContact O-CB 3.43Å; K210-S214 PolarHBondContact O-N 2.87Å; K210-S214 PolarHBondContact O-OG 2.87Å; E211-S214 PolarHBondContact O-N 2.71Å; E211-S214 PolarHBondContact O-OG 3.48Å; I212-S214 VanDerWaalsContact C-N 3.26Å; I212-S214 PolarHBondContact O-N 3.36Å
215M86.3Confident86.7Confident71 Ų7155 Ų5535%0.3528%0.284SS..Hα-helixtrans-88.1-11.3176.6-61.2179.170.700112.8E211 I212 R213 N217 V220 I260 V264E211-M215 WeakPolarHBondContact O-CG 3.23Å; E211-M215 PolarHBondContact O-N 2.76Å; I212-M215 WeakPolarHBondContact O-CB 3.48Å; I212-M215 PolarHBondContact O-N 3.1Å; R213-M215 PolarHBondContact O-N 3.27Å; M215-N217 PolarHBondContact O-N 3.05Å; M215-V220 VanDerWaalsContact O-CG2 3.25Å; M215-V220 WeakPolarHBondContact O-CG2 3.38Å; M215-I260 HydrophobicContact CE-CB 4.31Å; M215-I260 HydrophobicContact CE-CG1 4.16Å; M215-I260 HydrophobicContact CE-CG2 3.5Å; M215-I260 VanDerWaalsContact CE-CG2 3.5Å; M215-I260 HydrophobicContact SD-CG2 3.81Å; M215-V264 HydrophobicContact SD-CG2 3.91Å
216L84.4Confident86.7Confident22 Ų2255.8 Ų55.812%0.11529%0.287CS..  trans-70.394.7175.2-71.2-173.7000110.8I200 L201 S204 I212 R213 V220 Y224I200-L216 HydrophobicContact CG1-CD1 4.4Å; L201-L216 HydrophobicContact CD2-CB 4.45Å; L201-L216 HydrophobicContact CD2-CD1 4.41Å; S204-L216 VanDerWaalsContact OG-CD1 3.3Å; S204-L216 WeakPolarHBondContact OG-CD1 3.47Å; I212-L216 PolarHBondContact O-N 2.85Å; R213-L216 WeakPolarHBondContact O-CB 3.49Å; R213-L216 PolarHBondContact O-N 3.2Å; R213-L216 VanDerWaalsContact O-N 3.13Å; L216-V220 HydrophobicContact CD2-CB 4.18Å; L216-V220 HydrophobicContact CD2-CG1 3.57Å; L216-Y224 HydrophobicContact CD2-CD2 4.39Å; L216-Y224 HydrophobicContact CD2-CE2 3.78Å
217N84.1Confident86.7Confident84 Ų8455.6 Ų55.645%0.44929%0.285SS..SBendtrans-115.7-177.216863.624.3000110M215 Q219 V220 A221M215-N217 PolarHBondContact O-N 3.05Å; N217-Q219 PolarHBondContact O-N 2.79Å; N217-Q219 WeakPolarHBondContact OD1-CA 3.48Å; N217-Q219 WeakPolarHBondContact OD1-CB 3.42Å; N217-Q219 PolarHBondContact OD1-N 3.17Å; N217-V220 PolarHBondContact O-N 3.44Å; N217-V220 VanDerWaalsContact O-N 3.12Å; N217-V220 PolarHBondContact OD1-N 3.48Å; N217-V220 VanDerWaalsContact OD1-N 3.08Å; N217-A221 PolarHBondContact O-N 3.28Å
218E79.4Confident86.5Confident179 Ų17957.3 Ų57.384%0.83629%0.294SS*.Hα-helixtrans-54.4-35.8179.1-66.4177.5-177.900113.1A221 Q222E218-A221 PolarHBondContact O-N 3.24Å; E218-Q222 PolarHBondContact O-N 2.84Å
219Q84.2Confident86.3Confident150 Ų15058.8 Ų58.870%0.70131%0.31SS*.Hα-helixtrans-66.2-47.1178.6-61.3179-15.900111N217 A221 Q222 L223N217-Q219 PolarHBondContact O-N 2.79Å; N217-Q219 WeakPolarHBondContact OD1-CA 3.48Å; N217-Q219 WeakPolarHBondContact OD1-CB 3.42Å; N217-Q219 PolarHBondContact OD1-N 3.17Å; Q219-A221 VanDerWaalsContact C-N 3.35Å; Q219-Q222 WeakPolarHBondContact O-CB 3.38Å; Q219-Q222 PolarHBondContact O-N 2.89Å; Q219-L223 WeakPolarHBondContact O-CG 3.47Å; Q219-L223 PolarHBondContact O-N 3.49Å; Q219-L223 VanDerWaalsContact O-N 3.09Å
220V85.3Confident86.4Confident15 Ų1558.5 Ų58.59%0.09131%0.307CS..Hα-helixtrans-69.1-35.1179.3-175.50000111.4M215 L216 N217 Q222 L223 Y224 I260M215-V220 VanDerWaalsContact O-CG2 3.25Å; M215-V220 WeakPolarHBondContact O-CG2 3.38Å; L216-V220 HydrophobicContact CD2-CB 4.18Å; L216-V220 HydrophobicContact CD2-CG1 3.57Å; N217-V220 PolarHBondContact O-N 3.44Å; N217-V220 VanDerWaalsContact O-N 3.12Å; N217-V220 PolarHBondContact OD1-N 3.48Å; N217-V220 VanDerWaalsContact OD1-N 3.08Å; V220-Q222 VanDerWaalsContact C-N 3.31Å; V220-Q222 PolarHBondContact O-N 3.27Å; V220-L223 WeakPolarHBondContact O-CB 3.16Å; V220-L223 PolarHBondContact O-N 2.88Å; V220-L223 VanDerWaalsContact O-N 3.13Å; V220-Y224 HydrophobicContact CG1-CD2 4.09Å; V220-Y224 HydrophobicContact CG1-CE2 3.71Å; V220-Y224 VanDerWaalsContact O-CD2 3.25Å; V220-Y224 WeakPolarHBondContact O-CD2 3.45Å; V220-Y224 PolarHBondContact O-N 2.9Å; V220-Y224 VanDerWaalsContact O-N 3.09Å; V220-I260 HydrophobicContact CG2-CD1 3.93Å
221A84.5Confident86.4Confident38 Ų3853.2 Ų53.231%0.31428%0.284SS..Hα-helixtrans-60.3-40.1171.900000112.1N217 E218 Q219 L223 Y224 T225N217-A221 PolarHBondContact O-N 3.28Å; E218-A221 PolarHBondContact O-N 3.24Å; Q219-A221 VanDerWaalsContact C-N 3.35Å; A221-L223 VanDerWaalsContact C-N 3.34Å; A221-L223 PolarHBondContact O-N 3.01Å; A221-Y224 PolarHBondContact O-N 2.76Å; A221-T225 PolarHBondContact O-N 3.13Å; A221-T225 PolarHBondContact O-OG1 2.96Å; A221-T225 VanDerWaalsContact O-OG1 3.07Å
222Q87.6Confident86.2Confident99 Ų9952 Ų5246%0.46328%0.282SS..Hα-helixtrans-65.1-36.3173.7-173.859.456.200112.2E218 Q219 V220 Y224 T225 D226E218-Q222 PolarHBondContact O-N 2.84Å; Q219-Q222 WeakPolarHBondContact O-CB 3.38Å; Q219-Q222 PolarHBondContact O-N 2.89Å; V220-Q222 VanDerWaalsContact C-N 3.31Å; V220-Q222 PolarHBondContact O-N 3.27Å; Q222-Y224 VanDerWaalsContact C-N 3.33Å; Q222-Y224 PolarHBondContact O-N 2.83Å; Q222-T225 WeakPolarHBondContact O-CB 3.37Å; Q222-T225 PolarHBondContact O-N 3.44Å; Q222-D226 PolarHBondContact NE2-OD1 3.2Å; Q222-D226 PolarHBondContact O-N 3.18Å
223L91.9Very high85.7Confident19 Ų1956.5 Ų56.510%0.09930%0.302CS..Hα-helixtrans-62.8-39.6174.5-61.5176.9000111.7Q219 V220 A221 D226 L227 A253 E256 I257Q219-L223 WeakPolarHBondContact O-CG 3.47Å; Q219-L223 PolarHBondContact O-N 3.49Å; Q219-L223 VanDerWaalsContact O-N 3.09Å; V220-L223 WeakPolarHBondContact O-CB 3.16Å; V220-L223 PolarHBondContact O-N 2.88Å; V220-L223 VanDerWaalsContact O-N 3.13Å; A221-L223 VanDerWaalsContact C-N 3.34Å; A221-L223 PolarHBondContact O-N 3.01Å; L223-D226 PolarHBondContact O-N 3.03Å; L223-L227 PolarHBondContact O-N 3.38Å; L223-A253 HydrophobicContact CB-CB 4.14Å; L223-A253 HydrophobicContact CD2-CB 4.08Å; L223-A253 VanDerWaalsContact O-CB 3.28Å; L223-A253 WeakPolarHBondContact O-CB 3.28Å; L223-E256 HydrophobicContact CD1-CB 3.84Å; L223-E256 HydrophobicContact CD2-CB 4.27Å; L223-E256 WeakPolarHBondContact CD2-OE2 3.39Å; L223-I257 HydrophobicContact CB-CD1 3.6Å; L223-I257 HydrophobicContact CB-CG1 3.82Å; L223-I257 HydrophobicContact CD1-CG1 4.02Å
224Y87.8Confident85.2Confident6 Ų655.5 Ų55.52%0.02431%0.306CS..Hα-helixtrans-65.1-40.3173.4-76.6-65.5000112.5I200 L216 V220 A221 Q222 D226 L227 D228 I257 F261 L306 L307I200-Y224 HydrophobicContact CD1-CD2 3.75Å; I200-Y224 HydrophobicContact CD1-CE2 4.46Å; I200-Y224 HydrophobicContact CD1-CG 4.1Å; L216-Y224 HydrophobicContact CD2-CD2 4.39Å; L216-Y224 HydrophobicContact CD2-CE2 3.78Å; V220-Y224 HydrophobicContact CG1-CD2 4.09Å; V220-Y224 HydrophobicContact CG1-CE2 3.71Å; V220-Y224 VanDerWaalsContact O-CD2 3.25Å; V220-Y224 WeakPolarHBondContact O-CD2 3.45Å; V220-Y224 PolarHBondContact O-N 2.9Å; V220-Y224 VanDerWaalsContact O-N 3.09Å; A221-Y224 PolarHBondContact O-N 2.76Å; Q222-Y224 VanDerWaalsContact C-N 3.33Å; Q222-Y224 PolarHBondContact O-N 2.83Å; Y224-D226 VanDerWaalsContact C-N 3.3Å; Y224-D226 PolarHBondContact O-N 2.91Å; Y224-L227 HydrophobicContact CD1-CD1 4.17Å; Y224-L227 HydrophobicContact CE1-CD1 4.4Å; Y224-L227 WeakPolarHBondContact O-CB 3.21Å; Y224-L227 PolarHBondContact O-N 3.5Å; Y224-D228 VanDerWaalsContact O-CG 3.28Å; Y224-D228 PolarHBondContact O-N 3.13Å; Y224-I257 HydrophobicContact CD1-CD1 3.89Å; Y224-I257 HydrophobicContact CD2-CD1 4.42Å; Y224-I257 HydrophobicContact CE1-CD1 3.78Å; Y224-I257 HydrophobicContact CE1-CG2 4.5Å; Y224-I257 HydrophobicContact CE2-CD1 4.37Å; Y224-I257 HydrophobicContact CG-CD1 4.19Å; Y224-F261 WeakPolarHBondContact OH-CZ 3.23Å; Y224-L306 HydrophobicContact CD1-CD2 3.96Å; Y224-L306 HydrophobicContact CD2-CD2 4.12Å; Y224-L306 HydrophobicContact CE1-CD2 3.42Å; Y224-L306 VanDerWaalsContact CE1-CD2 3.42Å; Y224-L306 HydrophobicContact CE1-CG 4.49Å; Y224-L306 HydrophobicContact CE2-CD2 3.55Å; Y224-L306 HydrophobicContact CG-CD2 4.29Å; Y224-L306 WeakPolarHBondContact OH-CD2 3.36Å; Y224-L307 HydrophobicContact CD1-CD2 4.34Å
225T86.8Confident85Confident78 Ų7851.1 Ų51.148%0.47928%0.275SS..Hα-helixtrans-60.5-40.9174-56.80000111.6A221 Q222 D228 G229A221-T225 PolarHBondContact O-N 3.13Å; A221-T225 PolarHBondContact O-OG1 2.96Å; A221-T225 VanDerWaalsContact O-OG1 3.07Å; Q222-T225 WeakPolarHBondContact O-CB 3.37Å; Q222-T225 PolarHBondContact O-N 3.44Å; T225-D228 WeakPolarHBondContact O-CB 3.48Å; T225-D228 PolarHBondContact O-N 2.68Å; T225-G229 PolarHBondContact O-N 3.38Å
226D91.3Very high84.7Confident29 Ų2950.2 Ų50.216%0.15527%0.268CS..Hα-helixtrans-68.4-35.5176.9-79.10.3000112Q222 L223 Y224 G229 K249 R250 A253Q222-D226 PolarHBondContact NE2-OD1 3.2Å; Q222-D226 PolarHBondContact O-N 3.18Å; L223-D226 PolarHBondContact O-N 3.03Å; Y224-D226 VanDerWaalsContact C-N 3.3Å; Y224-D226 PolarHBondContact O-N 2.91Å; D226-G229 PolarHBondContact O-N 3.35Å; D226-K249 HydrophobicContact CB-CB 4.18Å; D226-R250 WeakPolarHBondContact O-CA 3.37Å; D226-A253 HydrophobicContact CB-CB 3.72Å
227L91.1Very high84.3Confident0 Ų052.8 Ų52.80%028%0.282CS..Hα-helixtrans-62.9-44.3170.1-82-178000111.7V135 L223 Y224 G229 G230 R250 A253 H254 I257 I303V135-L227 HydrophobicContact CG1-CB 4.33Å; V135-L227 HydrophobicContact CG1-CD2 4.24Å; L223-L227 PolarHBondContact O-N 3.38Å; Y224-L227 HydrophobicContact CD1-CD1 4.17Å; Y224-L227 HydrophobicContact CE1-CD1 4.4Å; Y224-L227 WeakPolarHBondContact O-CB 3.21Å; Y224-L227 PolarHBondContact O-N 3.5Å; L227-G229 PolarHBondContact O-N 2.89Å; L227-G230 WeakPolarHBondContact O-CA 3.19Å; L227-G230 PolarHBondContact O-N 3.27Å; L227-R250 HydrophobicContact CD2-CG 4.24Å; L227-A253 HydrophobicContact CD2-CB 4.36Å; L227-A253 HydrophobicContact CG-CB 4.05Å; L227-H254 HydrophobicContact CD2-CB 3.76Å; L227-I257 HydrophobicContact CD1-CD1 3.34Å; L227-I257 HydrophobicContact CG-CD1 4.05Å; L227-I303 HydrophobicContact CD1-CG2 3.94Å
228D86.7Confident84Confident38 Ų3852.1 Ų52.120%0.20328%0.277CS..Hα-helixtrans-62-32.1178.3-72.9-30.6000112.4Y224 T225 G230 F231 L307 H311Y224-D228 VanDerWaalsContact O-CG 3.28Å; Y224-D228 PolarHBondContact O-N 3.13Å; T225-D228 WeakPolarHBondContact O-CB 3.48Å; T225-D228 PolarHBondContact O-N 2.68Å; D228-G230 PolarHBondContact O-N 3.38Å; D228-F231 WeakPolarHBondContact O-CB 3.2Å; D228-F231 PolarHBondContact O-N 3.04Å; D228-L307 WeakPolarHBondContact OD1-CD2 3.32Å; D228-H311 VanDerWaalsContact CG-CE1 3.46Å; D228-H311 IonicContact OD1-CD2 3.01Å; D228-H311 IonicContact OD1-CE1 2.62Å; D228-H311 IonicContact OD1-NE2 3.71Å; D228-H311 PolarHBondContact OD1-NE2 3.41Å; D228-H311 IonicContact OD2-CE1 3.56Å; D228-H311 PolarHBondContact OD2-CE1 3.35Å; D228-H311 IonicContact OD2-NE2 3.43Å; D228-H311 PolarHBondContact OD2-NE2 2.84Å
229G84.2Confident84Confident31 Ų3145.9 Ų45.932%0.3225%0.253SS..THydrogen-bonded Turntrans-57.4-16.8170.200000114.2T225 D226 L227 F231T225-G229 PolarHBondContact O-N 3.38Å; D226-G229 PolarHBondContact O-N 3.35Å; L227-G229 PolarHBondContact O-N 2.89Å; G229-F231 VanDerWaalsContact C-N 3.27Å; G229-F231 PolarHBondContact O-N 3.02Å
230G84.8Confident83.5Confident0 Ų041.9 Ų41.90%024%0.239CC..THydrogen-bonded Turntrans-68.4-22.2170.800000114.4L227 D228 S232 A235L227-G230 WeakPolarHBondContact O-CA 3.19Å; L227-G230 PolarHBondContact O-N 3.27Å; D228-G230 PolarHBondContact O-N 3.38Å; G230-S232 VanDerWaalsContact C-N 3.34Å; G230-S232 PolarHBondContact O-N 3.12Å; G230-A235 WeakPolarHBondContact O-CB 3.3Å
231F85.3Confident83.2Confident51 Ų5150.9 Ų50.922%0.22427%0.271CS..SBendtrans-93.260.5-179.7-71.5-48.9000111.2T132 V135 F136 D228 G229 L307 M481T132-F231 HydrophobicContact CG2-CE1 4.01Å; V135-F231 HydrophobicContact CB-CE1 4.46Å; V135-F231 HydrophobicContact CB-CE2 4.31Å; V135-F231 HydrophobicContact CB-CZ 3.91Å; V135-F231 HydrophobicContact CG1-CE2 3.75Å; V135-F231 HydrophobicContact CG1-CZ 3.78Å; V135-F231 HydrophobicContact CG2-CE1 4.07Å; V135-F231 HydrophobicContact CG2-CE2 4.17Å; V135-F231 HydrophobicContact CG2-CZ 3.88Å; F136-F231 HydrophobicContact CE1-CE2 4.46Å; F136-F231 AromaticContact CE1-CZ 3.92Å; F136-F231 HydrophobicContact CE1-CZ 3.92Å; F136-F231 AromaticContact CZ-CZ 3.95Å; F136-F231 HydrophobicContact CZ-CZ 3.95Å; D228-F231 WeakPolarHBondContact O-CB 3.2Å; D228-F231 PolarHBondContact O-N 3.04Å; G229-F231 VanDerWaalsContact C-N 3.27Å; G229-F231 PolarHBondContact O-N 3.02Å; F231-L307 HydrophobicContact CE2-CD1 4.18Å; F231-M481 VanDerWaalsContact C-CE 3.4Å; F231-M481 VanDerWaalsContact CA-CE 3.47Å; F231-M481 HydrophobicContact CB-CE 3.26Å; F231-M481 HydrophobicContact CD1-CE 3.9Å; F231-M481 HydrophobicContact CG-CE 3.92Å; F231-M481 VanDerWaalsContact O-CE 3.23Å; F231-M481 WeakPolarHBondContact O-CE 3.42Å
232S80.9Confident83.2Confident30 Ų3050.6 Ų50.621%0.2127%0.265CS..SBendtrans-116.1156.4-178.762.30000112.8G230 A234 A235 W236G230-S232 VanDerWaalsContact C-N 3.34Å; G230-S232 PolarHBondContact O-N 3.12Å; S232-A234 PolarHBondContact O-N 3.37Å; S232-A235 WeakPolarHBondContact O-CB 3.19Å; S232-A235 PolarHBondContact O-N 3.22Å; S232-A235 PolarHBondContact OG-N 3.46Å; S232-W236 PolarHBondContact O-N 3.41Å; S232-W236 VanDerWaalsContact O-N 3.09Å
233H77.1Confident83Confident98 Ų9850.6 Ų50.645%0.45427%0.274SS..Hα-helixtrans-52.5-36.1168.9-69.298.5000112W236 L237 T479H233-W236 PolarHBondContact O-N 3.1Å; H233-L237 WeakPolarHBondContact O-CG 3.3Å; H233-L237 PolarHBondContact O-N 2.86Å; H233-L237 VanDerWaalsContact O-N 3.11Å; H233-T479 PolarHBondContact CE1-O 3.44Å; H233-T479 PolarHBondContact ND1-O 2.71Å
234A78.4Confident82.9Confident34 Ų3452 Ų5228%0.28128%0.281SS..Hα-helixtrans-63.4-43.7175.400000112S232 W236 L237 L238 L244S232-A234 PolarHBondContact O-N 3.37Å; A234-W236 VanDerWaalsContact C-N 3.3Å; A234-W236 PolarHBondContact O-N 3.14Å; A234-L237 PolarHBondContact O-N 3.28Å; A234-L238 HydrophobicContact CB-CD1 4.25Å; A234-L238 VanDerWaalsContact O-CB 3.25Å; A234-L238 WeakPolarHBondContact O-CB 3.23Å; A234-L238 WeakPolarHBondContact O-CG 3.37Å; A234-L238 PolarHBondContact O-N 3.48Å; A234-L244 HydrophobicContact CB-CD1 4.07Å
235A82.6Confident83Confident2 Ų256.3 Ų56.32%0.01731%0.31CS..Hα-helixtrans-64.2-34.3176.600000112.9L131 G230 S232 F247L131-A235 HydrophobicContact CD2-CB 3.6Å; G230-A235 WeakPolarHBondContact O-CB 3.3Å; S232-A235 WeakPolarHBondContact O-CB 3.19Å; S232-A235 PolarHBondContact O-N 3.22Å; S232-A235 PolarHBondContact OG-N 3.46Å; A235-F247 HydrophobicContact CB-CE1 3.72Å; A235-F247 HydrophobicContact CB-CZ 4.02Å
236W79.4Confident83.1Confident52 Ų5254.5 Ų54.520%0.19730%0.3CS..Hα-helixtrans-67.3-45.7176.9-177.362.5000111.3V98 F102 K130 L131 S232 H233 A234V98-W236 HydrophobicContact CG2-CZ3 4.42Å; F102-W236 HydrophobicContact CE1-CZ2 4.36Å; F102-W236 HydrophobicContact CE2-CH2 4.27Å; F102-W236 AromaticContact CZ-CH2 3.61Å; F102-W236 HydrophobicContact CZ-CH2 3.61Å; F102-W236 AromaticContact CZ-CZ2 3.63Å; F102-W236 HydrophobicContact CZ-CZ2 3.63Å; K130-W236 PolarHBondContact NZ-O 3.38Å; L131-W236 HydrophobicContact CD1-CB 4.23Å; L131-W236 HydrophobicContact CD1-CG 4.38Å; L131-W236 HydrophobicContact CD2-CB 4.03Å; L131-W236 HydrophobicContact CG-CB 4.44Å; S232-W236 PolarHBondContact O-N 3.41Å; S232-W236 VanDerWaalsContact O-N 3.09Å; H233-W236 PolarHBondContact O-N 3.1Å; A234-W236 VanDerWaalsContact C-N 3.3Å; A234-W236 PolarHBondContact O-N 3.14Å
237L76.4Confident83.1Confident76 Ų7653.2 Ų53.240%0.39829%0.293SS..Hα-helixtrans-83.3-45.4-173.8-66.9177.6000114V98 K130 H233 A234V98-L237 HydrophobicContact CB-CD2 3.64Å; V98-L237 HydrophobicContact CG1-CD1 4.08Å; V98-L237 HydrophobicContact CG1-CD2 3.41Å; V98-L237 VanDerWaalsContact CG1-CD2 3.41Å; V98-L237 HydrophobicContact CG1-CG 4.32Å; V98-L237 HydrophobicContact CG2-CD1 4.22Å; V98-L237 HydrophobicContact CG2-CD2 3.94Å; K130-L237 PolarHBondContact NZ-O 3.45Å; H233-L237 WeakPolarHBondContact O-CG 3.3Å; H233-L237 PolarHBondContact O-N 2.86Å; H233-L237 VanDerWaalsContact O-N 3.11Å; A234-L237 PolarHBondContact O-N 3.28Å
238L78.4Confident83.2Confident69 Ų6961.7 Ų61.736%0.36133%0.325SS..SBendtrans-86.1150.7-171-60.7173.1000111.5K130 A234 V242 L244K130-L238 WeakPolarHBondContact CE-O 3.36Å; K130-L238 PolarHBondContact NZ-O 3.46Å; A234-L238 HydrophobicContact CB-CD1 4.25Å; A234-L238 VanDerWaalsContact O-CB 3.25Å; A234-L238 WeakPolarHBondContact O-CB 3.23Å; A234-L238 WeakPolarHBondContact O-CG 3.37Å; A234-L238 PolarHBondContact O-N 3.48Å; L238-V242 HydrophobicContact CB-CG2 4.34Å; L238-L244 HydrophobicContact CD1-CD1 3.77Å
239P78.2Confident83.5Confident49 Ų4965.4 Ų65.432%0.31834%0.34SS..  trans-59.2146.5170.7-22.133.2000112W241 V242P239-W241 HydrophobicContact CB-CD2 3.9Å; P239-W241 HydrophobicContact CB-CG 4.11Å; P239-W241 HydrophobicContact CB-CZ2 3.71Å; P239-W241 HydrophobicContact CG-CH2 4.36Å; P239-W241 HydrophobicContact CG-CZ2 3.66Å; P239-W241 PolarHBondContact O-N 3.3Å; P239-V242 HydrophobicContact CB-CG2 4.35Å; P239-V242 HydrophobicContact CG-CG2 4.48Å; P239-V242 WeakPolarHBondContact O-CG2 3.48Å; P239-V242 PolarHBondContact O-N 2.93Å
240T75Confident84Confident66 Ų6664.1 Ų64.141%0.40533%0.325SS..THydrogen-bonded Turntrans-65.3-19.9-176.3500000113.9K130 P134 V242K130-T240 HydrophobicContact CG-CG2 4.05Å; P134-T240 HydrophobicContact CG-CG2 4.26Å; T240-V242 VanDerWaalsContact C-N 3.32Å
241W77.6Confident84.5Confident204 Ų20467.1 Ų67.177%0.77334%0.341SS*.THydrogen-bonded Turntrans-80.5-6.6178.152.2-104.9000114.2P239 P243P239-W241 HydrophobicContact CB-CD2 3.9Å; P239-W241 HydrophobicContact CB-CG 4.11Å; P239-W241 HydrophobicContact CB-CZ2 3.71Å; P239-W241 HydrophobicContact CG-CH2 4.36Å; P239-W241 HydrophobicContact CG-CZ2 3.66Å; P239-W241 PolarHBondContact O-N 3.3Å; W241-P243 WeakPolarHBondContact O-CD 3.3Å
242V85.5Confident85Confident32 Ų3271.7 Ų71.719%0.19436%0.357CS..SBendtrans-67.7124176.3-179.50000108.9L238 P239 T240 L244 F247L238-V242 HydrophobicContact CB-CG2 4.34Å; P239-V242 HydrophobicContact CB-CG2 4.35Å; P239-V242 HydrophobicContact CG-CG2 4.48Å; P239-V242 WeakPolarHBondContact O-CG2 3.48Å; P239-V242 PolarHBondContact O-N 2.93Å; T240-V242 VanDerWaalsContact C-N 3.32Å; V242-L244 HydrophobicContact CG1-CD2 4.17Å; V242-L244 HydrophobicContact CG1-CG 3.92Å; V242-L244 PolarHBondContact O-N 3.48Å; V242-F247 HydrophobicContact CB-CE2 4.46Å; V242-F247 WeakPolarHBondContact O-CD2 3.31Å
243P84.3Confident85.7Confident98 Ų9870.3 Ų70.364%0.63635%0.347SS*.  trans-81.152.4-170.134.2-37.9000112.9W241W241-P243 WeakPolarHBondContact O-CD 3.3Å
244L89.1Confident86.6Confident50 Ų5066.8 Ų66.826%0.26233%0.331SS..  trans-65.4144.2176.2-67.4-176.6000111A234 L238 V242 S246 F247 R248A234-L244 HydrophobicContact CB-CD1 4.07Å; L238-L244 HydrophobicContact CD1-CD1 3.77Å; V242-L244 HydrophobicContact CG1-CD2 4.17Å; V242-L244 HydrophobicContact CG1-CG 3.92Å; V242-L244 PolarHBondContact O-N 3.48Å; L244-S246 PolarHBondContact O-N 3.27Å; L244-F247 HydrophobicContact CB-CB 4.48Å; L244-F247 HydrophobicContact CB-CD1 4.32Å; L244-F247 HydrophobicContact CB-CD2 4.29Å; L244-F247 HydrophobicContact CB-CG 4.12Å; L244-F247 HydrophobicContact CD1-CE1 4.08Å; L244-F247 HydrophobicContact CD1-CE2 4.16Å; L244-F247 HydrophobicContact CD1-CZ 3.82Å; L244-F247 HydrophobicContact CG-CE2 4.46Å; L244-F247 PolarHBondContact O-N 2.81Å; L244-R248 PolarHBondContact O-N 2.77Å; L244-R248 VanDerWaalsContact O-N 3.07Å
245P89.7Confident87.4Confident95 Ų9572.8 Ų72.862%0.61735%0.346SS*.Hα-helixtrans-53.3-39.9176.9-2835.2000113.3R248 K249P245-R248 PolarHBondContact O-N 3.22Å; P245-K249 WeakPolarHBondContact O-CB 3.15Å; P245-K249 WeakPolarHBondContact O-CG 3.27Å; P245-K249 PolarHBondContact O-N 2.96Å
246S88.2Confident88Confident40 Ų4075.9 Ų75.928%0.2836%0.36SS..Hα-helixtrans-64-39.3176.853.80000112.8L244 K249 R250L244-S246 PolarHBondContact O-N 3.27Å; S246-K249 PolarHBondContact O-N 2.94Å; S246-R250 WeakPolarHBondContact O-CB 3.4Å; S246-R250 PolarHBondContact O-N 3.5Å
247F91.1Very high88.7Confident3 Ų373.4 Ų73.41%0.01335%0.351CS..Hα-helixtrans-69.1-40.7178.9-64.63.2000110.8A235 V242 L244 K249 R250 D251A235-F247 HydrophobicContact CB-CE1 3.72Å; A235-F247 HydrophobicContact CB-CZ 4.02Å; V242-F247 HydrophobicContact CB-CE2 4.46Å; V242-F247 WeakPolarHBondContact O-CD2 3.31Å; L244-F247 HydrophobicContact CB-CB 4.48Å; L244-F247 HydrophobicContact CB-CD1 4.32Å; L244-F247 HydrophobicContact CB-CD2 4.29Å; L244-F247 HydrophobicContact CB-CG 4.12Å; L244-F247 HydrophobicContact CD1-CE1 4.08Å; L244-F247 HydrophobicContact CD1-CE2 4.16Å; L244-F247 HydrophobicContact CD1-CZ 3.82Å; L244-F247 HydrophobicContact CG-CE2 4.46Å; L244-F247 PolarHBondContact O-N 2.81Å; F247-K249 PolarHBondContact O-N 3.02Å; F247-R250 PolarHBondContact O-N 3.24Å; F247-D251 WeakPolarHBondContact O-CB 3.22Å; F247-D251 PolarHBondContact O-N 3.35Å
248R93.3Very high89.6Confident178 Ų17870.4 Ų70.467%0.67234%0.335SS*.Hα-helixtrans-64.5-40.8176.5-62.8-179.381.4174.85.1111.8L244 P245 R252L244-R248 PolarHBondContact O-N 2.77Å; L244-R248 VanDerWaalsContact O-N 3.07Å; P245-R248 PolarHBondContact O-N 3.22Å; R248-R252 WeakPolarHBondContact O-CB 3.44Å; R248-R252 PolarHBondContact O-N 3.14Å
249K94.5Very high90.4Very high115 Ų11571.3 Ų71.350%0.534%0.34SS..Hα-helixtrans-62.7-49.3174-76.3-176176.2-166.50111.4D226 P245 S246 F247 D251 R252 A253D226-K249 HydrophobicContact CB-CB 4.18Å; P245-K249 WeakPolarHBondContact O-CB 3.15Å; P245-K249 WeakPolarHBondContact O-CG 3.27Å; P245-K249 PolarHBondContact O-N 2.96Å; S246-K249 PolarHBondContact O-N 2.94Å; F247-K249 PolarHBondContact O-N 3.02Å; K249-D251 PolarHBondContact O-N 3.19Å; K249-R252 WeakPolarHBondContact O-CB 3.25Å; K249-R252 PolarHBondContact O-N 3.45Å; K249-A253 WeakPolarHBondContact O-CB 3.08Å; K249-A253 PolarHBondContact O-N 3.15Å
250R94.6Very high91.1Very high5 Ų570.3 Ų70.32%0.01933%0.332CS..Hα-helixtrans-52.2-53.1173.9177.6-157.266-154.9-5111.7V135 D226 L227 S246 F247 R252 A253 H254V135-R250 HydrophobicContact CG2-CG 4.23Å; D226-R250 WeakPolarHBondContact O-CA 3.37Å; L227-R250 HydrophobicContact CD2-CG 4.24Å; S246-R250 WeakPolarHBondContact O-CB 3.4Å; S246-R250 PolarHBondContact O-N 3.5Å; F247-R250 PolarHBondContact O-N 3.24Å; R250-R252 VanDerWaalsContact C-N 3.29Å; R250-R252 PolarHBondContact O-N 3Å; R250-A253 PolarHBondContact O-N 2.99Å; R250-H254 WeakPolarHBondContact O-CB 3.33Å; R250-H254 PolarHBondContact O-N 3.43Å
251D94.1Very high92Very high62 Ų6267.3 Ų67.333%0.33231%0.313SS..Hα-helixtrans-67.4-30.9-175.6-63.7-14.8000112.5F247 K249 R255F247-D251 WeakPolarHBondContact O-CB 3.22Å; F247-D251 PolarHBondContact O-N 3.35Å; K249-D251 PolarHBondContact O-N 3.19Å; D251-R255 WeakPolarHBondContact O-CG 3.21Å; D251-R255 PolarHBondContact O-N 3.13Å; D251-R255 PolarHBondContact O-NE 3.32Å
252R95.9Very high92.9Very high147 Ų14760.3 Ų60.356%0.55529%0.288SS*.Hα-helixtrans-67.5-52.3170.9179.6-177.2173.4-165.4-8.7110.6R248 K249 R250 H254 R255 E256R248-R252 WeakPolarHBondContact O-CB 3.44Å; R248-R252 PolarHBondContact O-N 3.14Å; K249-R252 WeakPolarHBondContact O-CB 3.25Å; K249-R252 PolarHBondContact O-N 3.45Å; R250-R252 VanDerWaalsContact C-N 3.29Å; R250-R252 PolarHBondContact O-N 3Å; R252-H254 VanDerWaalsContact C-N 3.31Å; R252-H254 PolarHBondContact O-N 3.05Å; R252-R255 PolarHBondContact O-N 2.83Å; R252-R255 VanDerWaalsContact O-N 3.14Å; R252-E256 WeakPolarHBondContact CG-OE1 3.48Å; R252-E256 IonicContact CZ-OE1 3.15Å; R252-E256 IonicContact NE-OE1 3.07Å; R252-E256 PolarHBondContact NE-OE1 3.03Å; R252-E256 IonicContact NH2-OE1 3.9Å; R252-E256 PolarHBondContact NH2-OE1 2.99Å; R252-E256 PolarHBondContact O-N 3.35Å
253A95.8Very high93.3Very high1 Ų165.7 Ų65.71%0.00831%0.309CS..Hα-helixtrans-60.2-40.6-178.900000112.6L223 D226 L227 K249 R250 R255 E256 I257L223-A253 HydrophobicContact CB-CB 4.14Å; L223-A253 HydrophobicContact CD2-CB 4.08Å; L223-A253 VanDerWaalsContact O-CB 3.28Å; L223-A253 WeakPolarHBondContact O-CB 3.28Å; D226-A253 HydrophobicContact CB-CB 3.72Å; L227-A253 HydrophobicContact CD2-CB 4.36Å; L227-A253 HydrophobicContact CG-CB 4.05Å; K249-A253 WeakPolarHBondContact O-CB 3.08Å; K249-A253 PolarHBondContact O-N 3.15Å; R250-A253 PolarHBondContact O-N 2.99Å; A253-R255 VanDerWaalsContact C-N 3.33Å; A253-R255 PolarHBondContact O-N 3.43Å; A253-E256 PolarHBondContact O-N 3.25Å; A253-I257 WeakPolarHBondContact O-CB 3.37Å; A253-I257 WeakPolarHBondContact O-CG1 3.33Å; A253-I257 PolarHBondContact O-N 2.86Å
254H95.6Very high93.7Very high24 Ų2461.6 Ų61.611%0.11128%0.282CS..Hα-helixtrans-53.7-48.5173.4-178.278.9000112.3V135 F136 G137 L227 R250 R252 K258V135-H254 PolarHBondContact O-CE1 3.24Å; V135-H254 PolarHBondContact O-ND1 2.93Å; F136-H254 VanDerWaalsContact C-CE1 3.47Å; F136-H254 PolarHBondContact O-CE1 3.44Å; G137-H254 WeakPolarHBondContact CA-CE1 3.28Å; G137-H254 PolarHBondContact N-CE1 2.7Å; G137-H254 VanDerWaalsContact N-CE1 3.31Å; L227-H254 HydrophobicContact CD2-CB 3.76Å; R250-H254 WeakPolarHBondContact O-CB 3.33Å; R250-H254 PolarHBondContact O-N 3.43Å; R252-H254 VanDerWaalsContact C-N 3.31Å; R252-H254 PolarHBondContact O-N 3.05Å; H254-K258 WeakPolarHBondContact CE1-CE 3.16Å; H254-K258 WeakPolarHBondContact NE2-CD 3.49Å; H254-K258 WeakPolarHBondContact NE2-CE 3.47Å; H254-K258 PolarHBondContact NE2-NZ 2.75Å; H254-K258 WeakPolarHBondContact O-CB 3.23Å; H254-K258 WeakPolarHBondContact O-CG 3.39Å; H254-K258 PolarHBondContact O-N 3Å
255R96.4Very high93.9Very high161 Ų16159.3 Ų59.361%0.60827%0.27SS*.Hα-helixtrans-67.5-42.5179.4-72.2-178.3-69.2-172.72.7112.2D251 R252 A253 K258 N259D251-R255 WeakPolarHBondContact O-CG 3.21Å; D251-R255 PolarHBondContact O-N 3.13Å; D251-R255 PolarHBondContact O-NE 3.32Å; R252-R255 PolarHBondContact O-N 2.83Å; R252-R255 VanDerWaalsContact O-N 3.14Å; A253-R255 VanDerWaalsContact C-N 3.33Å; A253-R255 PolarHBondContact O-N 3.43Å; R255-K258 PolarHBondContact O-N 2.84Å; R255-N259 WeakPolarHBondContact O-CB 3.34Å; R255-N259 PolarHBondContact O-N 3.23Å; R255-N259 PolarHBondContact O-ND2 2.83Å
256E95.6Very high94.1Very high66 Ų6659.2 Ų59.231%0.30826%0.262SS..Hα-helixtrans-65.4-43.5180-70.4-174.6-160.900111.8L223 R252 A253 N259 I260L223-E256 HydrophobicContact CD1-CB 3.84Å; L223-E256 HydrophobicContact CD2-CB 4.27Å; L223-E256 WeakPolarHBondContact CD2-OE2 3.39Å; R252-E256 WeakPolarHBondContact CG-OE1 3.48Å; R252-E256 IonicContact CZ-OE1 3.15Å; R252-E256 IonicContact NE-OE1 3.07Å; R252-E256 PolarHBondContact NE-OE1 3.03Å; R252-E256 IonicContact NH2-OE1 3.9Å; R252-E256 PolarHBondContact NH2-OE1 2.99Å; R252-E256 PolarHBondContact O-N 3.35Å; A253-E256 PolarHBondContact O-N 3.25Å; E256-N259 PolarHBondContact O-N 3.25Å; E256-I260 PolarHBondContact O-N 2.98Å; E256-I260 VanDerWaalsContact O-N 3.13Å
257I94.3Very high94.3Very high1 Ų164.5 Ų64.51%0.00528%0.279CS..Hα-helixtrans-65.1-43.8175.8-72.1167000111.3L223 Y224 L227 A253 N259 I260 F261 I303L223-I257 HydrophobicContact CB-CD1 3.6Å; L223-I257 HydrophobicContact CB-CG1 3.82Å; L223-I257 HydrophobicContact CD1-CG1 4.02Å; Y224-I257 HydrophobicContact CD1-CD1 3.89Å; Y224-I257 HydrophobicContact CD2-CD1 4.42Å; Y224-I257 HydrophobicContact CE1-CD1 3.78Å; Y224-I257 HydrophobicContact CE1-CG2 4.5Å; Y224-I257 HydrophobicContact CE2-CD1 4.37Å; Y224-I257 HydrophobicContact CG-CD1 4.19Å; L227-I257 HydrophobicContact CD1-CD1 3.34Å; L227-I257 HydrophobicContact CG-CD1 4.05Å; A253-I257 WeakPolarHBondContact O-CB 3.37Å; A253-I257 WeakPolarHBondContact O-CG1 3.33Å; A253-I257 PolarHBondContact O-N 2.86Å; I257-N259 VanDerWaalsContact C-N 3.3Å; I257-N259 PolarHBondContact O-N 3.18Å; I257-I260 WeakPolarHBondContact O-CB 3.16Å; I257-I260 PolarHBondContact O-N 2.93Å; I257-I260 VanDerWaalsContact O-N 3.1Å; I257-F261 HydrophobicContact CG2-CD2 4.03Å; I257-F261 HydrophobicContact CG2-CE1 4.38Å; I257-F261 HydrophobicContact CG2-CE2 3.62Å; I257-F261 HydrophobicContact CG2-CZ 3.82Å; I257-F261 PolarHBondContact O-N 2.8Å; I257-I303 HydrophobicContact CG2-CD1 3.97Å; I257-I303 HydrophobicContact CG2-CG1 3.8Å
258K95.1Very high94.2Very high12 Ų1264.8 Ų64.85%0.05228%0.28CS..Hα-helixtrans-58.8-42.1175-81.9-166.1163.8178.50112.3H254 R255 I260 F261 F262 D296 A299 I303H254-K258 WeakPolarHBondContact CE1-CE 3.16Å; H254-K258 WeakPolarHBondContact NE2-CD 3.49Å; H254-K258 WeakPolarHBondContact NE2-CE 3.47Å; H254-K258 PolarHBondContact NE2-NZ 2.75Å; H254-K258 WeakPolarHBondContact O-CB 3.23Å; H254-K258 WeakPolarHBondContact O-CG 3.39Å; H254-K258 PolarHBondContact O-N 3Å; R255-K258 PolarHBondContact O-N 2.84Å; K258-I260 VanDerWaalsContact C-N 3.27Å; K258-I260 PolarHBondContact O-N 2.83Å; K258-F261 PolarHBondContact O-N 3.22Å; K258-F261 VanDerWaalsContact O-N 3.12Å; K258-F262 HydrophobicContact CB-CE1 4.47Å; K258-F262 HydrophobicContact CB-CE2 4.08Å; K258-F262 HydrophobicContact CB-CZ 3.99Å; K258-F262 HydrophobicContact CD-CZ 4.19Å; K258-F262 HydrophobicContact CG-CZ 4.48Å; K258-F262 WeakPolarHBondContact O-CD1 3.48Å; K258-F262 WeakPolarHBondContact O-CD2 3.32Å; K258-F262 WeakPolarHBondContact O-CG 3.19Å; K258-F262 PolarHBondContact O-N 3.44Å; K258-D296 WeakPolarHBondContact CD-OD1 3.19Å; K258-D296 WeakPolarHBondContact CE-OD1 3.49Å; K258-D296 IonicContact NZ-OD1 3.21Å; K258-D296 PolarHBondContact NZ-OD1 2.94Å; K258-D296 IonicContact NZ-OD2 3.46Å; K258-D296 PolarHBondContact NZ-OD2 3.49Å; K258-A299 HydrophobicContact CG-CB 4.07Å; K258-I303 HydrophobicContact CG-CD1 4.05Å
259N94.8Very high94.1Very high88 Ų8861.7 Ų61.747%0.47127%0.269SS..Hα-helixtrans-62.5-33.9176.6-71.4-23.8000112.9R255 E256 I257 K263R255-N259 WeakPolarHBondContact O-CB 3.34Å; R255-N259 PolarHBondContact O-N 3.23Å; R255-N259 PolarHBondContact O-ND2 2.83Å; E256-N259 PolarHBondContact O-N 3.25Å; I257-N259 VanDerWaalsContact C-N 3.3Å; I257-N259 PolarHBondContact O-N 3.18Å; N259-K263 WeakPolarHBondContact O-CG 3.24Å; N259-K263 PolarHBondContact O-N 3.43Å
260I92.8Very high94Very high29 Ų2963.6 Ų63.615%0.14928%0.277CS..Hα-helixtrans-63.3-50.3172-70.2167.3000109.7M215 V220 E256 I257 K258 F262 K263 V264M215-I260 HydrophobicContact CE-CB 4.31Å; M215-I260 HydrophobicContact CE-CG1 4.16Å; M215-I260 HydrophobicContact CE-CG2 3.5Å; M215-I260 VanDerWaalsContact CE-CG2 3.5Å; M215-I260 HydrophobicContact SD-CG2 3.81Å; V220-I260 HydrophobicContact CG2-CD1 3.93Å; E256-I260 PolarHBondContact O-N 2.98Å; E256-I260 VanDerWaalsContact O-N 3.13Å; I257-I260 WeakPolarHBondContact O-CB 3.16Å; I257-I260 PolarHBondContact O-N 2.93Å; I257-I260 VanDerWaalsContact O-N 3.1Å; K258-I260 VanDerWaalsContact C-N 3.27Å; K258-I260 PolarHBondContact O-N 2.83Å; I260-F262 PolarHBondContact O-N 3.29Å; I260-K263 PolarHBondContact O-N 3.34Å; I260-V264 PolarHBondContact O-N 3.14Å
261F94.3Very high93.8Very high2 Ų266 Ų661%0.00930%0.295CS..Hα-helixtrans-63.7-39.8-179.2-65.4-17000113H208 I212 Y224 I257 K258 K263 V264 I265 A299 L302 I303H208-F261 AromaticContact CE1-CZ 3.92Å; I212-F261 HydrophobicContact CD1-CD1 3.69Å; I212-F261 HydrophobicContact CD1-CE1 3.73Å; I212-F261 HydrophobicContact CG1-CD1 4.12Å; I212-F261 HydrophobicContact CG1-CE1 4.11Å; I212-F261 HydrophobicContact CG2-CD1 4.46Å; I212-F261 HydrophobicContact CG2-CE1 3.66Å; I212-F261 HydrophobicContact CG2-CZ 4.49Å; Y224-F261 WeakPolarHBondContact OH-CZ 3.23Å; I257-F261 HydrophobicContact CG2-CD2 4.03Å; I257-F261 HydrophobicContact CG2-CE1 4.38Å; I257-F261 HydrophobicContact CG2-CE2 3.62Å; I257-F261 HydrophobicContact CG2-CZ 3.82Å; I257-F261 PolarHBondContact O-N 2.8Å; K258-F261 PolarHBondContact O-N 3.22Å; K258-F261 VanDerWaalsContact O-N 3.12Å; F261-K263 VanDerWaalsContact C-N 3.33Å; F261-K263 PolarHBondContact O-N 2.92Å; F261-V264 PolarHBondContact O-N 3.41Å; F261-V264 VanDerWaalsContact O-N 3.14Å; F261-I265 HydrophobicContact CB-CD1 4.45Å; F261-I265 WeakPolarHBondContact O-CB 3.48Å; F261-I265 WeakPolarHBondContact O-CD1 3.34Å; F261-I265 VanDerWaalsContact O-CG1 3.23Å; F261-I265 WeakPolarHBondContact O-CG1 3.48Å; F261-I265 PolarHBondContact O-N 3.43Å; F261-A299 HydrophobicContact CB-CB 3.85Å; F261-A299 HydrophobicContact CD2-CB 3.99Å; F261-A299 HydrophobicContact CG-CB 4.45Å; F261-L302 HydrophobicContact CD2-CB 3.98Å; F261-L302 HydrophobicContact CD2-CD1 4.22Å; F261-L302 HydrophobicContact CE2-CB 3.62Å; F261-L302 HydrophobicContact CG-CD1 4.27Å; F261-L302 HydrophobicContact CZ-CB 4.15Å; F261-I303 HydrophobicContact CD2-CG1 4.24Å; F261-I303 HydrophobicContact CE2-CG1 3.67Å
262F95.4Very high93.1Very high57 Ų5766.1 Ų66.125%0.2531%0.31CS..Hα-helixtrans-57.7-44.5175.6-63.3-22.3000112.2K258 I260 V264 I265 E266 D295 D296 A299K258-F262 HydrophobicContact CB-CE1 4.47Å; K258-F262 HydrophobicContact CB-CE2 4.08Å; K258-F262 HydrophobicContact CB-CZ 3.99Å; K258-F262 HydrophobicContact CD-CZ 4.19Å; K258-F262 HydrophobicContact CG-CZ 4.48Å; K258-F262 WeakPolarHBondContact O-CD1 3.48Å; K258-F262 WeakPolarHBondContact O-CD2 3.32Å; K258-F262 WeakPolarHBondContact O-CG 3.19Å; K258-F262 PolarHBondContact O-N 3.44Å; I260-F262 PolarHBondContact O-N 3.29Å; F262-V264 VanDerWaalsContact C-N 3.31Å; F262-V264 PolarHBondContact O-N 2.85Å; F262-I265 PolarHBondContact O-N 3.35Å; F262-E266 VanDerWaalsContact O-CB 3.25Å; F262-E266 WeakPolarHBondContact O-CB 3.3Å; F262-E266 PolarHBondContact O-N 2.85Å; F262-D295 HydrophobicContact CD1-CB 3.94Å; F262-D295 HydrophobicContact CE1-CB 4.11Å; F262-D295 WeakPolarHBondContact CE1-O 3.44Å; F262-D296 HydrophobicContact CZ-CB 4.41Å; F262-A299 HydrophobicContact CD1-CB 4.2Å; F262-A299 HydrophobicContact CE1-CB 3.75Å
263K94.1Very high92.4Very high146 Ų14665.7 Ų65.764%0.63531%0.314SS*.Hα-helixtrans-62.4-39.4177.1-69.7174.2-176.7-179.10112.2N259 I260 F261 K267N259-K263 WeakPolarHBondContact O-CG 3.24Å; N259-K263 PolarHBondContact O-N 3.43Å; I260-K263 PolarHBondContact O-N 3.34Å; F261-K263 VanDerWaalsContact C-N 3.33Å; F261-K263 PolarHBondContact O-N 2.92Å; K263-K267 VanDerWaalsContact O-CB 3.28Å; K263-K267 WeakPolarHBondContact O-CB 3.21Å; K263-K267 PolarHBondContact O-N 3.07Å
264V92.9Very high91.6Very high12 Ų1271.4 Ų71.47%0.07335%0.349CS..Hα-helixtrans-69.6-46.5178.8177.30000111E211 I212 M215 I260 F261 F262 E266 K267 R268 L279E211-V264 HydrophobicContact CB-CG1 3.94Å; I212-V264 HydrophobicContact CD1-CG1 4.4Å; I212-V264 HydrophobicContact CG1-CB 4.34Å; I212-V264 HydrophobicContact CG1-CG1 4.04Å; I212-V264 HydrophobicContact CG1-CG2 4.07Å; M215-V264 HydrophobicContact SD-CG2 3.91Å; I260-V264 PolarHBondContact O-N 3.14Å; F261-V264 PolarHBondContact O-N 3.41Å; F261-V264 VanDerWaalsContact O-N 3.14Å; F262-V264 VanDerWaalsContact C-N 3.31Å; F262-V264 PolarHBondContact O-N 2.85Å; V264-E266 PolarHBondContact O-N 3.4Å; V264-K267 PolarHBondContact O-N 3.27Å; V264-R268 PolarHBondContact O-N 3.11Å; V264-L279 HydrophobicContact CG1-CD2 3.75Å
265I93.1Very high90.9Very high1 Ų172 Ų721%0.00536%0.359CS..Hα-helixtrans-59.7-47.4177.9-66.9160.6000110.4F261 F262 K267 R268 R269 L279 I283 D295 I298F261-I265 HydrophobicContact CB-CD1 4.45Å; F261-I265 WeakPolarHBondContact O-CB 3.48Å; F261-I265 WeakPolarHBondContact O-CD1 3.34Å; F261-I265 VanDerWaalsContact O-CG1 3.23Å; F261-I265 WeakPolarHBondContact O-CG1 3.48Å; F261-I265 PolarHBondContact O-N 3.43Å; F262-I265 PolarHBondContact O-N 3.35Å; I265-K267 PolarHBondContact O-N 3.39Å; I265-R268 PolarHBondContact O-N 2.97Å; I265-R269 PolarHBondContact O-N 2.94Å; I265-L279 HydrophobicContact CG1-CD1 3.99Å; I265-I283 HydrophobicContact CG2-CD1 4.44Å; I265-I283 HydrophobicContact CG2-CG1 4.42Å; I265-D295 HydrophobicContact CD1-CB 4.43Å; I265-I298 HydrophobicContact CD1-CB 3.93Å; I265-I298 HydrophobicContact CD1-CG2 3.63Å; I265-I298 HydrophobicContact CG1-CG2 4.16Å
266E93.8Very high90.2Very high94 Ų9470.7 Ų70.744%0.43936%0.364SS..Hα-helixtrans-61-45.7178.4-173.4-173.8-176.800111.4F262 V264 R269 K270F262-E266 VanDerWaalsContact O-CB 3.25Å; F262-E266 WeakPolarHBondContact O-CB 3.3Å; F262-E266 PolarHBondContact O-N 2.85Å; V264-E266 PolarHBondContact O-N 3.4Å; E266-R269 PolarHBondContact O-N 3.33Å; E266-K270 HydrophobicContact CG-CD 4.14Å; E266-K270 WeakPolarHBondContact O-CB 3.23Å; E266-K270 WeakPolarHBondContact O-CG 3.46Å; E266-K270 PolarHBondContact O-N 2.7Å; E266-K270 WeakPolarHBondContact OE1-CE 3.37Å; E266-K270 IonicContact OE1-NZ 3.26Å; E266-K270 PolarHBondContact OE1-NZ 3.43Å
267K92.3Very high89.7Confident150 Ų15068.5 Ų68.565%0.65235%0.354SS*.Hα-helixtrans-60.6-46.6177.5-178-178.8175-171.80111.4K263 V264 I265 K270 S271K263-K267 VanDerWaalsContact O-CB 3.28Å; K263-K267 WeakPolarHBondContact O-CB 3.21Å; K263-K267 PolarHBondContact O-N 3.07Å; V264-K267 PolarHBondContact O-N 3.27Å; I265-K267 PolarHBondContact O-N 3.39Å; K267-K270 PolarHBondContact O-N 3.38Å; K267-S271 WeakPolarHBondContact O-CB 2.99Å; K267-S271 PolarHBondContact O-N 3.37Å; K267-S271 PolarHBondContact O-OG 3.3Å
268R90.4Very high89.4Confident9 Ų968.6 Ų68.63%0.03436%0.355CS..Hα-helixtrans-60-49.8-180-174.567.675.981.9-5.4110.7E211 V264 I265 K270 S271 G272 E273 D277 I283E211-R268 IonicContact OE1-CZ 2.62Å; E211-R268 IonicContact OE1-NE 3.32Å; E211-R268 PolarHBondContact OE1-NE 3.47Å; E211-R268 IonicContact OE1-NH2 3.78Å; E211-R268 PolarHBondContact OE1-NH2 3.44Å; E211-R268 IonicContact OE2-NH2 2.78Å; E211-R268 PolarHBondContact OE2-NH2 3.15Å; E211-R268 VanDerWaalsContact OE2-NH2 3.13Å; V264-R268 PolarHBondContact O-N 3.11Å; I265-R268 PolarHBondContact O-N 2.97Å; R268-K270 VanDerWaalsContact C-N 3.32Å; R268-K270 PolarHBondContact O-N 2.7Å; R268-S271 PolarHBondContact O-N 3.41Å; R268-S271 PolarHBondContact O-OG 3.38Å; R268-G272 PolarHBondContact O-N 3.05Å; R268-E273 WeakPolarHBondContact CD-O 3.41Å; R268-D277 IonicContact CZ-OD2 2.86Å; R268-D277 IonicContact NH1-OD1 3.81Å; R268-D277 PolarHBondContact NH1-OD1 3.13Å; R268-D277 IonicContact NH1-OD2 2.71Å; R268-D277 PolarHBondContact NH1-OD2 3.13Å; R268-D277 IonicContact NH2-OD1 3.49Å; R268-D277 IonicContact NH2-OD2 3.34Å; R268-D277 PolarHBondContact NH2-OD2 3.35Å; R268-I283 HydrophobicContact CB-CD1 4.06Å; R268-I283 HydrophobicContact CG-CD1 3.87Å
269R90.7Very high89.2Confident114 Ų11468 Ų6843%0.4335%0.352SS..Hα-helixtrans-59.4-38.2177.1-74-176.8174.3159.64.5113.5I265 E266 I283 D295I265-R269 PolarHBondContact O-N 2.94Å; E266-R269 PolarHBondContact O-N 3.33Å; R269-I283 HydrophobicContact CG-CG2 4.08Å; R269-D295 IonicContact CZ-OD1 3.8Å; R269-D295 VanDerWaalsContact CZ-OD1 3.26Å; R269-D295 IonicContact NH1-OD1 3.63Å; R269-D295 PolarHBondContact NH1-OD1 3.42Å; R269-D295 IonicContact NH1-OD2 2.89Å; R269-D295 IonicContact NH2-OD1 2.81Å; R269-D295 PolarHBondContact NH2-OD1 3.06Å
270K92.8Very high89Confident154 Ų15464.8 Ų64.867%0.6733%0.334SS*.Hα-helixtrans-73.4-33.5178.8-76.9177.6173.7174.20113.5E266 K267 R268 G272E266-K270 HydrophobicContact CG-CD 4.14Å; E266-K270 WeakPolarHBondContact O-CB 3.23Å; E266-K270 WeakPolarHBondContact O-CG 3.46Å; E266-K270 PolarHBondContact O-N 2.7Å; E266-K270 WeakPolarHBondContact OE1-CE 3.37Å; E266-K270 IonicContact OE1-NZ 3.26Å; E266-K270 PolarHBondContact OE1-NZ 3.43Å; K267-K270 PolarHBondContact O-N 3.38Å; R268-K270 VanDerWaalsContact C-N 3.32Å; R268-K270 PolarHBondContact O-N 2.7Å; K270-G272 VanDerWaalsContact C-N 3.33Å
271S89.9Confident88.9Confident57 Ų5764.9 Ų64.940%0.39934%0.336SS..Hα-helixtrans-69.7-29.4-178.168.60000113.4K267 R268 E273K267-S271 WeakPolarHBondContact O-CB 2.99Å; K267-S271 PolarHBondContact O-N 3.37Å; K267-S271 PolarHBondContact O-OG 3.3Å; R268-S271 PolarHBondContact O-N 3.41Å; R268-S271 PolarHBondContact O-OG 3.38Å; S271-E273 PolarHBondContact O-N 3.16Å; S271-E273 PolarHBondContact OG-N 3.25Å
272G78.8Confident88.9Confident63 Ų6364.9 Ų64.965%0.64934%0.336SS*.  trans70.22.9-170.900000114R268 K270 T274R268-G272 PolarHBondContact O-N 3.05Å; K270-G272 VanDerWaalsContact C-N 3.33Å; G272-T274 PolarHBondContact O-N 2.86Å
273E81Confident88.7Confident138 Ų13863 Ų6365%0.64533%0.329SS*.  trans-70.7127.3174.2-66.7-180177.600109.6R268 S271R268-E273 WeakPolarHBondContact CD-O 3.41Å; S271-E273 PolarHBondContact O-N 3.16Å; S271-E273 PolarHBondContact OG-N 3.25Å
274T79.1Confident88.7Confident121 Ų12161 Ų6174%0.74233%0.325SS*.  trans-98.7128.5171.252.40000109.1G272G272-T274 PolarHBondContact O-N 2.86Å
275A81.8Confident88.8Confident37 Ų3761 Ų6131%0.30633%0.326SS..  trans-117.3145.2172.600000109.6D277 Q280A275-D277 PolarHBondContact O-N 2.85Å; A275-Q280 WeakPolarHBondContact O-CB 3.47Å; A275-Q280 WeakPolarHBondContact O-CG 3.25Å
276D82.1Confident89Confident133 Ų13365 Ų6571%0.71135%0.351SS*.SBendtrans-83.371.7173.8-161.832.1000109.2H164H164-D276 IonicContact CD2-OD2 3.9Å; H164-D276 PolarHBondContact NE2-O 3.07Å; H164-D276 IonicContact NE2-OD1 3.44Å; H164-D276 PolarHBondContact NE2-OD1 3.33Å; H164-D276 VanDerWaalsContact NE2-OD1 3.14Å; H164-D276 IonicContact NE2-OD2 2.83Å
277D85.2Confident89.1Confident21 Ų2160.9 Ų60.911%0.11233%0.331CS..SBendtrans-137.4170.5-179.968.524.2000113.1R268 A275 L279 Q280 T281R268-D277 IonicContact CZ-OD2 2.86Å; R268-D277 IonicContact NH1-OD1 3.81Å; R268-D277 PolarHBondContact NH1-OD1 3.13Å; R268-D277 IonicContact NH1-OD2 2.71Å; R268-D277 PolarHBondContact NH1-OD2 3.13Å; R268-D277 IonicContact NH2-OD1 3.49Å; R268-D277 IonicContact NH2-OD2 3.34Å; R268-D277 PolarHBondContact NH2-OD2 3.35Å; A275-D277 PolarHBondContact O-N 2.85Å; D277-L279 VanDerWaalsContact C-N 3.28Å; D277-L279 PolarHBondContact O-N 3.2Å; D277-L279 WeakPolarHBondContact OD1-CB 3.44Å; D277-L279 PolarHBondContact OD1-N 2.91Å; D277-Q280 PolarHBondContact O-N 3.19Å; D277-Q280 WeakPolarHBondContact OD1-CB 3.36Å; D277-Q280 PolarHBondContact OD1-N 3.34Å; D277-T281 PolarHBondContact O-N 2.97Å; D277-T281 PolarHBondContact O-OG1 3.49Å
278I87.3Confident89.3Confident3 Ų361.9 Ų61.92%0.01534%0.336CS..Hα-helixtrans-61.6-37.4178.7-69-82.9000111.3L160 L207 T281 L282 L302 L305L160-I278 HydrophobicContact CD2-CD1 4.33Å; L207-I278 HydrophobicContact CD2-CG1 4.45Å; L207-I278 VanDerWaalsContact O-CB 3.23Å; L207-I278 WeakPolarHBondContact O-CB 3.05Å; L207-I278 VanDerWaalsContact O-CG2 3.24Å; L207-I278 WeakPolarHBondContact O-CG2 3.36Å; I278-T281 WeakPolarHBondContact O-CB 3.22Å; I278-T281 PolarHBondContact O-N 3.26Å; I278-L282 HydrophobicContact CG2-CD1 4.12Å; I278-L282 HydrophobicContact CG2-CG 4.4Å; I278-L282 WeakPolarHBondContact O-CG 3.31Å; I278-L282 PolarHBondContact O-N 2.93Å; I278-L302 HydrophobicContact CG2-CD2 4.47Å; I278-L305 HydrophobicContact CG2-CD2 3.77Å
279L90.7Very high89.6Confident0 Ų067.3 Ų67.30%037%0.366CS..Hα-helixtrans-63.1-47.2-179174.862.8000110.5V264 I265 D277 T281 L282 I283 I298 L302V264-L279 HydrophobicContact CG1-CD2 3.75Å; I265-L279 HydrophobicContact CG1-CD1 3.99Å; D277-L279 VanDerWaalsContact C-N 3.28Å; D277-L279 PolarHBondContact O-N 3.2Å; D277-L279 WeakPolarHBondContact OD1-CB 3.44Å; D277-L279 PolarHBondContact OD1-N 2.91Å; L279-T281 VanDerWaalsContact C-N 3.34Å; L279-L282 PolarHBondContact O-N 2.96Å; L279-I283 HydrophobicContact CD1-CD1 4.09Å; L279-I283 HydrophobicContact CD1-CG1 4.39Å; L279-I283 HydrophobicContact CG-CD1 3.97Å; L279-I283 WeakPolarHBondContact O-CG1 3.37Å; L279-I283 PolarHBondContact O-N 3.21Å; L279-I298 HydrophobicContact CD1-CG2 4.26Å; L279-L302 HydrophobicContact CD1-CD1 3.97Å
280Q90.2Very high89.9Confident19 Ų1964.3 Ų64.39%0.08937%0.37CS..Hα-helixtrans-62.4-43.9175.8-167.861.345.100111A275 D277 L282 I283 D284A275-Q280 WeakPolarHBondContact O-CB 3.47Å; A275-Q280 WeakPolarHBondContact O-CG 3.25Å; D277-Q280 PolarHBondContact O-N 3.19Å; D277-Q280 WeakPolarHBondContact OD1-CB 3.36Å; D277-Q280 PolarHBondContact OD1-N 3.34Å; Q280-L282 PolarHBondContact O-N 3.36Å; Q280-I283 PolarHBondContact O-N 2.75Å; Q280-I283 VanDerWaalsContact O-N 3.11Å; Q280-D284 WeakPolarHBondContact CG-OD2 3.36Å; Q280-D284 PolarHBondContact NE2-OD1 3.4Å; Q280-D284 PolarHBondContact NE2-OD2 2.9Å; Q280-D284 WeakPolarHBondContact O-CB 2.98Å; Q280-D284 PolarHBondContact O-N 3.37Å
281T90.9Very high90.1Very high32 Ų3261.4 Ų61.420%0.19636%0.355CS..Hα-helixtrans-54.2-40.7175.3-58.60000111.9T158 D277 I278 L279 A285T158-T281 WeakPolarHBondContact OG1-CG2 3.38Å; D277-T281 PolarHBondContact O-N 2.97Å; D277-T281 PolarHBondContact O-OG1 3.49Å; I278-T281 WeakPolarHBondContact O-CB 3.22Å; I278-T281 PolarHBondContact O-N 3.26Å; L279-T281 VanDerWaalsContact C-N 3.34Å; T281-A285 WeakPolarHBondContact O-CB 3.4Å; T281-A285 PolarHBondContact O-N 3.25Å
282L93.5Very high90.4Very high1 Ų162.2 Ų62.21%0.00536%0.359CS..Hα-helixtrans-76.3-36.8177.8-67.3176.6000112.8M155 L156 I278 L279 Q280 D284 A285 L293 I298 M301 L302M155-L282 HydrophobicContact CB-CD2 4.32Å; L156-L282 HydrophobicContact CD2-CD1 4.32Å; L156-L282 HydrophobicContact CD2-CD2 4.13Å; I278-L282 HydrophobicContact CG2-CD1 4.12Å; I278-L282 HydrophobicContact CG2-CG 4.4Å; I278-L282 WeakPolarHBondContact O-CG 3.31Å; I278-L282 PolarHBondContact O-N 2.93Å; L279-L282 PolarHBondContact O-N 2.96Å; Q280-L282 PolarHBondContact O-N 3.36Å; L282-D284 VanDerWaalsContact C-N 3.27Å; L282-D284 PolarHBondContact O-N 3.14Å; L282-A285 PolarHBondContact O-N 3.43Å; L282-L293 HydrophobicContact CB-CD1 4.29Å; L282-L293 HydrophobicContact CD2-CD1 4Å; L282-L293 WeakPolarHBondContact O-CD1 3.35Å; L282-I298 HydrophobicContact CB-CG1 4.39Å; L282-I298 HydrophobicContact CB-CG2 4.12Å; L282-I298 HydrophobicContact CD1-CG2 4.31Å; L282-M301 HydrophobicContact CD1-CB 4.37Å; L282-M301 HydrophobicContact CD2-CE 3.58Å; L282-M301 HydrophobicContact CD2-SD 4.35Å; L282-L302 HydrophobicContact CD1-CD2 3.94Å; L282-L302 HydrophobicContact CD1-CG 4.23Å
283I93.3Very high91.3Very high19 Ų1959.4 Ų59.410%0.09733%0.329CS..Hα-helixtrans-61.5-39.2175.5-73.2169.6000110.9I265 R268 R269 L279 Q280 I298I265-I283 HydrophobicContact CG2-CD1 4.44Å; I265-I283 HydrophobicContact CG2-CG1 4.42Å; R268-I283 HydrophobicContact CB-CD1 4.06Å; R268-I283 HydrophobicContact CG-CD1 3.87Å; R269-I283 HydrophobicContact CG-CG2 4.08Å; L279-I283 HydrophobicContact CD1-CD1 4.09Å; L279-I283 HydrophobicContact CD1-CG1 4.39Å; L279-I283 HydrophobicContact CG-CD1 3.97Å; L279-I283 WeakPolarHBondContact O-CG1 3.37Å; L279-I283 PolarHBondContact O-N 3.21Å; Q280-I283 PolarHBondContact O-N 2.75Å; Q280-I283 VanDerWaalsContact O-N 3.11Å; I283-I298 HydrophobicContact CG1-CD1 4.16Å
284D93.2Very high92.1Very high103 Ų10356.1 Ų56.155%0.55132%0.318SS*.SBendtrans-87.9-6.7-176.9-61.1-21.6000113.1Q280 L282Q280-D284 WeakPolarHBondContact CG-OD2 3.36Å; Q280-D284 PolarHBondContact NE2-OD1 3.4Å; Q280-D284 PolarHBondContact NE2-OD2 2.9Å; Q280-D284 WeakPolarHBondContact O-CB 2.98Å; Q280-D284 PolarHBondContact O-N 3.37Å; L282-D284 VanDerWaalsContact C-N 3.27Å; L282-D284 PolarHBondContact O-N 3.14Å
285A94.8Very high93Very high13 Ų1352.6 Ų52.611%0.10730%0.295CS..  trans-73.6142.6-17800000112.7M155 T281 L282 L293M155-A285 HydrophobicContact CB-CB 4.3Å; M155-A285 HydrophobicContact CE-CB 4.41Å; M155-A285 HydrophobicContact CG-CB 3.92Å; M155-A285 HydrophobicContact SD-CB 3.99Å; T281-A285 WeakPolarHBondContact O-CB 3.4Å; T281-A285 PolarHBondContact O-N 3.25Å; L282-A285 PolarHBondContact O-N 3.43Å; A285-L293 HydrophobicContact CB-CD1 4.06Å; A285-L293 HydrophobicContact CB-CG 4.47Å; A285-L293 PolarHBondContact O-N 3.39Å
286T96.4Very high93.7Very high85 Ų8553.6 Ų53.652%0.52130%0.295SS..BIsolated β-bridgetrans-128.1142.7172.652.80000110.7M155 R291 P292M155-T286 VanDerWaalsContact CE-C 3.46Å; M155-T286 VanDerWaalsContact CE-O 3.25Å; M155-T286 WeakPolarHBondContact CE-O 3.31Å; T286-R291 WeakPolarHBondContact CA-O 3.41Å; T286-P292 HydrophobicContact CG2-CB 4.48Å
287Y97.8Very high94.5Very high7 Ų747.9 Ų47.93%0.02726%0.264CS..  trans-66.5166.4168-71-75.9000110.4I148 E151 Q152 M155 D289 G290 R291 L293 E297I148-Y287 HydrophobicContact CG2-CE1 3.83Å; E151-Y287 HydrophobicContact CB-CD1 3.98Å; E151-Y287 HydrophobicContact CB-CE1 4.28Å; Q152-Y287 HydrophobicContact CG-CE1 4.16Å; Q152-Y287 PolarHBondContact NE2-OH 3.41Å; M155-Y287 HydrophobicContact CE-CD1 3.68Å; M155-Y287 HydrophobicContact CE-CD2 4.44Å; M155-Y287 HydrophobicContact CE-CE1 4Å; M155-Y287 HydrophobicContact CE-CG 3.93Å; Y287-D289 VanDerWaalsContact CB-OD1 3.29Å; Y287-D289 WeakPolarHBondContact CB-OD1 3.23Å; Y287-D289 PolarHBondContact O-N 3.36Å; Y287-D289 VanDerWaalsContact O-N 3.17Å; Y287-G290 PolarHBondContact O-N 3.17Å; Y287-R291 HydrophobicContact CD2-CB 4.45Å; Y287-R291 WeakPolarHBondContact CD2-O 3.24Å; Y287-R291 PolarHBondContact N-O 3.17Å; Y287-L293 HydrophobicContact CD2-CD2 4.31Å; Y287-L293 HydrophobicContact CE1-CD2 4.4Å; Y287-L293 HydrophobicContact CE2-CD2 3.42Å; Y287-L293 VanDerWaalsContact CE2-CD2 3.42Å; Y287-L293 HydrophobicContact CE2-CG 4.47Å; Y287-L293 VanDerWaalsContact CZ-CD2 3.49Å; Y287-L293 WeakPolarHBondContact OH-CD2 3.4Å; Y287-E297 WeakPolarHBondContact CE2-OE1 3.25Å; Y287-E297 PolarHBondContact OH-OE1 2.76Å
288K96.1Very high95Very high171 Ų17146.9 Ų46.974%0.74326%0.259SS*.THydrogen-bonded Turntrans-60.3-25.7179.8-72.7178-168.3160.10114.4E151 G290E151-K288 HydrophobicContact CG-CD 4.46Å; E151-K288 HydrophobicContact CG-CG 4.49Å; E151-K288 WeakPolarHBondContact OE1-CD 3.37Å; E151-K288 IonicContact OE1-NZ 2.76Å; E151-K288 WeakPolarHBondContact OE2-CG 3.46Å; E151-K288 PolarHBondContact OE2-N 3.02Å; K288-G290 PolarHBondContact O-N 3.34Å
289D95.9Very high95.5Very high123 Ų12346.7 Ų46.766%0.65826%0.258SS*.THydrogen-bonded Turntrans-78.9-0.1175.565.60.4000113.2Y287 R291Y287-D289 VanDerWaalsContact CB-OD1 3.29Å; Y287-D289 WeakPolarHBondContact CB-OD1 3.23Å; Y287-D289 PolarHBondContact O-N 3.36Å; Y287-D289 VanDerWaalsContact O-N 3.17Å; D289-R291 VanDerWaalsContact C-N 3.34Å; D289-R291 WeakPolarHBondContact OD1-CB 3.12Å; D289-R291 PolarHBondContact OD1-N 2.88Å
290G96.4Very high95.8Very high51 Ų5146.8 Ų46.853%0.52626%0.258SS..SBendtrans87.3-3.5-178.600000114.2Y287 K288Y287-G290 PolarHBondContact O-N 3.17Å; K288-G290 PolarHBondContact O-N 3.34Å
291R97.4Very high96.1Very high93 Ų9346.3 Ų46.335%0.35126%0.256SS..PPolyproline II helixtrans-71.2129.9179.8-173178.963.287-15110.5T286 Y287 D289 E297T286-R291 WeakPolarHBondContact CA-O 3.41Å; Y287-R291 HydrophobicContact CD2-CB 4.45Å; Y287-R291 WeakPolarHBondContact CD2-O 3.24Å; Y287-R291 PolarHBondContact N-O 3.17Å; D289-R291 VanDerWaalsContact C-N 3.34Å; D289-R291 WeakPolarHBondContact OD1-CB 3.12Å; D289-R291 PolarHBondContact OD1-N 2.88Å; R291-E297 IonicContact CZ-OE1 2.73Å; R291-E297 IonicContact CZ-OE2 2.98Å; R291-E297 IonicContact NH1-OE1 3.17Å; R291-E297 PolarHBondContact NH1-OE1 3.43Å; R291-E297 IonicContact NH1-OE2 3.85Å; R291-E297 PolarHBondContact NH1-OE2 3.09Å; R291-E297 IonicContact NH2-OE1 3.36Å; R291-E297 PolarHBondContact NH2-OE1 3.35Å; R291-E297 IonicContact NH2-OE2 3.3Å
292P97.3Very high96.3Very high74 Ų7444.8 Ų44.848%0.48125%0.247SC..BIsolated β-bridgetrans-71.2160.5171.430.5-34.9000111.6T286T286-P292 HydrophobicContact CG2-CB 4.48Å
293L97.5Very high96.3Very high4 Ų444.7 Ų44.72%0.02125%0.247CC..PPolyproline II helixtrans-66134.4170-67.9176.4000110.6M155 L282 A285 Y287 E297 I298 M301M155-L293 HydrophobicContact SD-CD1 3.92Å; M155-L293 HydrophobicContact SD-CD2 4.02Å; M155-L293 HydrophobicContact SD-CG 4.16Å; L282-L293 HydrophobicContact CB-CD1 4.29Å; L282-L293 HydrophobicContact CD2-CD1 4Å; L282-L293 WeakPolarHBondContact O-CD1 3.35Å; A285-L293 HydrophobicContact CB-CD1 4.06Å; A285-L293 HydrophobicContact CB-CG 4.47Å; A285-L293 PolarHBondContact O-N 3.39Å; Y287-L293 HydrophobicContact CD2-CD2 4.31Å; Y287-L293 HydrophobicContact CE1-CD2 4.4Å; Y287-L293 HydrophobicContact CE2-CD2 3.42Å; Y287-L293 VanDerWaalsContact CE2-CD2 3.42Å; Y287-L293 HydrophobicContact CE2-CG 4.47Å; Y287-L293 VanDerWaalsContact CZ-CD2 3.49Å; Y287-L293 WeakPolarHBondContact OH-CD2 3.4Å; L293-E297 HydrophobicContact CD2-CB 4.15Å; L293-I298 HydrophobicContact CB-CD1 4.06Å; L293-I298 HydrophobicContact CB-CG1 3.61Å; L293-I298 HydrophobicContact CD1-CG1 4.09Å; L293-I298 HydrophobicContact CG-CG1 4.49Å; L293-M301 HydrophobicContact CD1-SD 3.96Å; L293-M301 HydrophobicContact CD2-SD 4.22Å
294T97.8Very high96.3Very high68 Ų6844.5 Ų44.542%0.41725%0.249SC..PPolyproline II helixtrans-72.8156.5168.261.70000110.5D296 E297 I298T294-D296 PolarHBondContact O-N 3.01Å; T294-E297 WeakPolarHBondContact CB-OE2 3.5Å; T294-E297 PolarHBondContact N-OE2 2.99Å; T294-E297 WeakPolarHBondContact O-CB 3.2Å; T294-E297 PolarHBondContact O-N 3.01Å; T294-E297 VanDerWaalsContact O-N 3.07Å; T294-E297 WeakPolarHBondContact OG1-CB 3.29Å; T294-E297 VanDerWaalsContact OG1-CG 3.27Å; T294-E297 WeakPolarHBondContact OG1-CG 3.37Å; T294-E297 PolarHBondContact OG1-N 2.84Å; T294-E297 PolarHBondContact OG1-OE2 2.83Å; T294-I298 WeakPolarHBondContact O-CG1 3.49Å; T294-I298 PolarHBondContact O-N 2.79Å
295D96.8Very high96.3Very high48 Ų4840.5 Ų40.526%0.25723%0.228SC..Hα-helixtrans-60.7-32.7179.5-658.6000111.8F262 I265 R269 I298 A299F262-D295 HydrophobicContact CD1-CB 3.94Å; F262-D295 HydrophobicContact CE1-CB 4.11Å; F262-D295 WeakPolarHBondContact CE1-O 3.44Å; I265-D295 HydrophobicContact CD1-CB 4.43Å; R269-D295 IonicContact CZ-OD1 3.8Å; R269-D295 VanDerWaalsContact CZ-OD1 3.26Å; R269-D295 IonicContact NH1-OD1 3.63Å; R269-D295 PolarHBondContact NH1-OD1 3.42Å; R269-D295 IonicContact NH1-OD2 2.89Å; R269-D295 IonicContact NH2-OD1 2.81Å; R269-D295 PolarHBondContact NH2-OD1 3.06Å; D295-I298 PolarHBondContact O-N 3.44Å; D295-A299 VanDerWaalsContact O-CB 3.23Å; D295-A299 WeakPolarHBondContact O-CB 3.48Å; D295-A299 PolarHBondContact O-N 3.42Å
296D97.4Very high96.1Very high57 Ų5739.9 Ų39.931%0.30522%0.223SC..Hα-helixtrans-66.9-40.7175.5-161.371.3000112.4K258 F262 T294 G300K258-D296 WeakPolarHBondContact CD-OD1 3.19Å; K258-D296 WeakPolarHBondContact CE-OD1 3.49Å; K258-D296 IonicContact NZ-OD1 3.21Å; K258-D296 PolarHBondContact NZ-OD1 2.94Å; K258-D296 IonicContact NZ-OD2 3.46Å; K258-D296 PolarHBondContact NZ-OD2 3.49Å; F262-D296 HydrophobicContact CZ-CB 4.41Å; T294-D296 PolarHBondContact O-N 3.01Å; D296-G300 PolarHBondContact O-N 3.02Å
297E98.2Very high95.7Very high13 Ų1336.3 Ų36.36%0.06120%0.2CC..Hα-helixtrans-64.6-46.9173.2-74166.3128.200110.8V140 Y287 R291 L293 T294 A299 G300 M301V140-E297 HydrophobicContact CG1-CB 4.21Å; V140-E297 HydrophobicContact CG1-CG 4.41Å; V140-E297 WeakPolarHBondContact CG1-O 3.48Å; Y287-E297 WeakPolarHBondContact CE2-OE1 3.25Å; Y287-E297 PolarHBondContact OH-OE1 2.76Å; R291-E297 IonicContact CZ-OE1 2.73Å; R291-E297 IonicContact CZ-OE2 2.98Å; R291-E297 IonicContact NH1-OE1 3.17Å; R291-E297 PolarHBondContact NH1-OE1 3.43Å; R291-E297 IonicContact NH1-OE2 3.85Å; R291-E297 PolarHBondContact NH1-OE2 3.09Å; R291-E297 IonicContact NH2-OE1 3.36Å; R291-E297 PolarHBondContact NH2-OE1 3.35Å; R291-E297 IonicContact NH2-OE2 3.3Å; L293-E297 HydrophobicContact CD2-CB 4.15Å; T294-E297 WeakPolarHBondContact CB-OE2 3.5Å; T294-E297 PolarHBondContact N-OE2 2.99Å; T294-E297 WeakPolarHBondContact O-CB 3.2Å; T294-E297 PolarHBondContact O-N 3.01Å; T294-E297 VanDerWaalsContact O-N 3.07Å; T294-E297 WeakPolarHBondContact OG1-CB 3.29Å; T294-E297 VanDerWaalsContact OG1-CG 3.27Å; T294-E297 WeakPolarHBondContact OG1-CG 3.37Å; T294-E297 PolarHBondContact OG1-N 2.84Å; T294-E297 PolarHBondContact OG1-OE2 2.83Å; E297-A299 PolarHBondContact O-N 3.37Å; E297-G300 PolarHBondContact O-N 3.11Å; E297-M301 WeakPolarHBondContact O-CB 3.46Å; E297-M301 VanDerWaalsContact O-CG 3.25Å; E297-M301 WeakPolarHBondContact O-CG 3.41Å; E297-M301 PolarHBondContact O-N 2.92Å
298I96.9Very high95.4Very high0 Ų038.8 Ų38.80%022%0.222CC..Hα-helixtrans-59.2-50.8177.5-62.8172.5000109.9I265 L279 L282 I283 L293 T294 D295 G300 M301 L302I265-I298 HydrophobicContact CD1-CB 3.93Å; I265-I298 HydrophobicContact CD1-CG2 3.63Å; I265-I298 HydrophobicContact CG1-CG2 4.16Å; L279-I298 HydrophobicContact CD1-CG2 4.26Å; L282-I298 HydrophobicContact CB-CG1 4.39Å; L282-I298 HydrophobicContact CB-CG2 4.12Å; L282-I298 HydrophobicContact CD1-CG2 4.31Å; I283-I298 HydrophobicContact CG1-CD1 4.16Å; L293-I298 HydrophobicContact CB-CD1 4.06Å; L293-I298 HydrophobicContact CB-CG1 3.61Å; L293-I298 HydrophobicContact CD1-CG1 4.09Å; L293-I298 HydrophobicContact CG-CG1 4.49Å; T294-I298 WeakPolarHBondContact O-CG1 3.49Å; T294-I298 PolarHBondContact O-N 2.79Å; D295-I298 PolarHBondContact O-N 3.44Å; I298-G300 VanDerWaalsContact C-N 3.32Å; I298-G300 PolarHBondContact O-N 3.01Å; I298-M301 PolarHBondContact O-N 3Å; I298-L302 HydrophobicContact CG2-CD1 3.98Å; I298-L302 HydrophobicContact CG2-CG 4.37Å; I298-L302 VanDerWaalsContact O-CG 3.31Å; I298-L302 WeakPolarHBondContact O-CG 3.4Å; I298-L302 PolarHBondContact O-N 3.38Å
299A96.2Very high95.1Very high0 Ų031 Ų310%019%0.191CC..Hα-helixtrans-59.4-43.4179.500000111.6K258 F261 F262 D295 E297 L302 I303K258-A299 HydrophobicContact CG-CB 4.07Å; F261-A299 HydrophobicContact CB-CB 3.85Å; F261-A299 HydrophobicContact CD2-CB 3.99Å; F261-A299 HydrophobicContact CG-CB 4.45Å; F262-A299 HydrophobicContact CD1-CB 4.2Å; F262-A299 HydrophobicContact CE1-CB 3.75Å; D295-A299 VanDerWaalsContact O-CB 3.23Å; D295-A299 WeakPolarHBondContact O-CB 3.48Å; D295-A299 PolarHBondContact O-N 3.42Å; E297-A299 PolarHBondContact O-N 3.37Å; A299-L302 PolarHBondContact O-N 3.5Å; A299-I303 WeakPolarHBondContact O-CG1 3.45Å; A299-I303 PolarHBondContact O-N 3.17Å
300G97.3Very high94.8Very high1 Ų126 Ų261%0.0116%0.163CC..Hα-helixtrans-64.8-38.917700000113.5F136 D296 E297 I298 I303 G304F136-G300 WeakPolarHBondContact O-CA 3.37Å; D296-G300 PolarHBondContact O-N 3.02Å; E297-G300 PolarHBondContact O-N 3.11Å; I298-G300 VanDerWaalsContact C-N 3.32Å; I298-G300 PolarHBondContact O-N 3.01Å; G300-I303 PolarHBondContact O-N 3.32Å; G300-G304 PolarHBondContact O-N 2.84Å
301M97Very high94.5Very high9 Ų925.6 Ų25.64%0.04415%0.148CC..Hα-helixtrans-65.2-39.3174.3-71.3174.970.500111.8V140 Q152 M155 L156 L282 L293 E297 I298 G304 L305V140-M301 HydrophobicContact CB-CG 4.38Å; V140-M301 HydrophobicContact CG1-CG 3.83Å; Q152-M301 HydrophobicContact CB-CE 3.83Å; Q152-M301 HydrophobicContact CB-SD 4.22Å; Q152-M301 HydrophobicContact CG-CE 4.26Å; Q152-M301 HydrophobicContact CG-SD 4.03Å; Q152-M301 WeakPolarHBondContact O-CE 3.34Å; M155-M301 HydrophobicContact CB-CE 4.46Å; L156-M301 HydrophobicContact CD1-CE 3.94Å; L156-M301 HydrophobicContact CD2-CE 3.94Å; L156-M301 HydrophobicContact CG-CE 3.56Å; L282-M301 HydrophobicContact CD1-CB 4.37Å; L282-M301 HydrophobicContact CD2-CE 3.58Å; L282-M301 HydrophobicContact CD2-SD 4.35Å; L293-M301 HydrophobicContact CD1-SD 3.96Å; L293-M301 HydrophobicContact CD2-SD 4.22Å; E297-M301 WeakPolarHBondContact O-CB 3.46Å; E297-M301 VanDerWaalsContact O-CG 3.25Å; E297-M301 WeakPolarHBondContact O-CG 3.41Å; E297-M301 PolarHBondContact O-N 2.92Å; I298-M301 PolarHBondContact O-N 3Å; M301-G304 PolarHBondContact O-N 3.21Å; M301-L305 VanDerWaalsContact O-CB 3.3Å; M301-L305 WeakPolarHBondContact O-CB 3.33Å; M301-L305 PolarHBondContact O-N 3.31Å
302L94.6Very high94.4Very high0 Ų023.1 Ų23.10%014%0.143CC..Hα-helixtrans-65.2-41.7175.4-68.1170.5000112.2H208 I212 F261 I278 L279 L282 I298 A299 L305 L306H208-L302 PolarHBondContact NE2-O 2.6Å; I212-L302 HydrophobicContact CD1-CD1 4.13Å; F261-L302 HydrophobicContact CD2-CB 3.98Å; F261-L302 HydrophobicContact CD2-CD1 4.22Å; F261-L302 HydrophobicContact CE2-CB 3.62Å; F261-L302 HydrophobicContact CG-CD1 4.27Å; F261-L302 HydrophobicContact CZ-CB 4.15Å; I278-L302 HydrophobicContact CG2-CD2 4.47Å; L279-L302 HydrophobicContact CD1-CD1 3.97Å; L282-L302 HydrophobicContact CD1-CD2 3.94Å; L282-L302 HydrophobicContact CD1-CG 4.23Å; I298-L302 HydrophobicContact CG2-CD1 3.98Å; I298-L302 HydrophobicContact CG2-CG 4.37Å; I298-L302 VanDerWaalsContact O-CG 3.31Å; I298-L302 WeakPolarHBondContact O-CG 3.4Å; I298-L302 PolarHBondContact O-N 3.38Å; A299-L302 PolarHBondContact O-N 3.5Å; L302-L305 PolarHBondContact O-N 3.2Å; L302-L306 PolarHBondContact O-N 2.86Å; L302-L306 VanDerWaalsContact O-N 3.17Å
303I94.6Very high94.5Very high0 Ų019.7 Ų19.70%012%0.121CC..Hα-helixtrans-58.7-50.8173.1-65.7173.9000109.7F136 L227 I257 K258 F261 A299 G300 L305 L306 L307F136-I303 HydrophobicContact CD1-CG2 4.16Å; L227-I303 HydrophobicContact CD1-CG2 3.94Å; I257-I303 HydrophobicContact CG2-CD1 3.97Å; I257-I303 HydrophobicContact CG2-CG1 3.8Å; K258-I303 HydrophobicContact CG-CD1 4.05Å; F261-I303 HydrophobicContact CD2-CG1 4.24Å; F261-I303 HydrophobicContact CE2-CG1 3.67Å; A299-I303 WeakPolarHBondContact O-CG1 3.45Å; A299-I303 PolarHBondContact O-N 3.17Å; G300-I303 PolarHBondContact O-N 3.32Å; I303-L305 VanDerWaalsContact C-N 3.3Å; I303-L305 PolarHBondContact O-N 3.29Å; I303-L306 PolarHBondContact O-N 3.17Å; I303-L307 HydrophobicContact CG2-CD1 3.82Å; I303-L307 HydrophobicContact CG2-CG 4.48Å; I303-L307 WeakPolarHBondContact O-CG 3.45Å; I303-L307 PolarHBondContact O-N 2.71Å; I303-L307 VanDerWaalsContact O-N 3.13Å
304G93.6Very high94.5Very high15 Ų1519.5 Ų19.516%0.15512%0.12CC..Hα-helixtrans-59.6-40.3-179.700000112.9G300 M301 A308G300-G304 PolarHBondContact O-N 2.84Å; M301-G304 PolarHBondContact O-N 3.21Å; G304-A308 VanDerWaalsContact O-CB 3.23Å; G304-A308 WeakPolarHBondContact O-CB 3.39Å; G304-A308 PolarHBondContact O-N 3.45Å
305L92.3Very high94.5Very high18 Ų1816.3 Ų16.39%0.09410%0.1CC..Hα-helixtrans-65.8-42.8-178.8-172.161.3000112.4L156 L207 I278 M301 L302 I303 G309L156-L305 HydrophobicContact CD2-CD1 4.44Å; L156-L305 HydrophobicContact CD2-CD2 4.09Å; L207-L305 HydrophobicContact CB-CD2 3.73Å; L207-L305 HydrophobicContact CB-CG 4.09Å; L207-L305 HydrophobicContact CD1-CD1 4.18Å; L207-L305 HydrophobicContact CD1-CD2 4.3Å; L207-L305 HydrophobicContact CD1-CG 3.82Å; L207-L305 HydrophobicContact CD2-CD2 4.38Å; L207-L305 HydrophobicContact CG-CD2 4.35Å; L207-L305 HydrophobicContact CG-CG 4.41Å; I278-L305 HydrophobicContact CG2-CD2 3.77Å; M301-L305 VanDerWaalsContact O-CB 3.3Å; M301-L305 WeakPolarHBondContact O-CB 3.33Å; M301-L305 PolarHBondContact O-N 3.31Å; L302-L305 PolarHBondContact O-N 3.2Å; I303-L305 VanDerWaalsContact C-N 3.3Å; I303-L305 PolarHBondContact O-N 3.29Å; L305-G309 PolarHBondContact O-N 2.86Å
306L90.4Very high94.6Very high1 Ų114.1 Ų14.11%0.0059%0.089CC..Hα-helixtrans-67.8-46.4177.7-174.665.7000111.8I200 A203 H208 Y224 L302 I303 A308 G309 Q310I200-L306 HydrophobicContact CD1-CD2 4.46Å; I200-L306 HydrophobicContact CG1-CD1 4.29Å; I200-L306 HydrophobicContact CG1-CD2 4.14Å; A203-L306 HydrophobicContact CB-CD1 3.67Å; H208-L306 VanDerWaalsContact CE1-CB 3.46Å; H208-L306 WeakPolarHBondContact CE1-CB 3.42Å; Y224-L306 HydrophobicContact CD1-CD2 3.96Å; Y224-L306 HydrophobicContact CD2-CD2 4.12Å; Y224-L306 HydrophobicContact CE1-CD2 3.42Å; Y224-L306 VanDerWaalsContact CE1-CD2 3.42Å; Y224-L306 HydrophobicContact CE1-CG 4.49Å; Y224-L306 HydrophobicContact CE2-CD2 3.55Å; Y224-L306 HydrophobicContact CG-CD2 4.29Å; Y224-L306 WeakPolarHBondContact OH-CD2 3.36Å; L302-L306 PolarHBondContact O-N 2.86Å; L302-L306 VanDerWaalsContact O-N 3.17Å; I303-L306 PolarHBondContact O-N 3.17Å; L306-A308 VanDerWaalsContact C-N 3.27Å; L306-A308 PolarHBondContact O-N 2.92Å; L306-G309 PolarHBondContact O-N 3.48Å; L306-Q310 WeakPolarHBondContact O-CB 3.43Å; L306-Q310 PolarHBondContact O-N 3.04Å
307L89.3Confident94.6Very high10 Ų1011.4 Ų11.45%0.0527%0.074CC..Hα-helixtrans-63-36.4179.3-68.8178.2000111.9V135 F136 Y224 D228 F231 I303V135-L307 HydrophobicContact CG1-CD1 3.48Å; V135-L307 VanDerWaalsContact CG1-CD1 3.48Å; F136-L307 HydrophobicContact CD1-CD1 4.21Å; F136-L307 HydrophobicContact CE1-CB 4.3Å; F136-L307 HydrophobicContact CE1-CD1 3.8Å; Y224-L307 HydrophobicContact CD1-CD2 4.34Å; D228-L307 WeakPolarHBondContact OD1-CD2 3.32Å; F231-L307 HydrophobicContact CE2-CD1 4.18Å; I303-L307 HydrophobicContact CG2-CD1 3.82Å; I303-L307 HydrophobicContact CG2-CG 4.48Å; I303-L307 WeakPolarHBondContact O-CG 3.45Å; I303-L307 PolarHBondContact O-N 2.71Å; I303-L307 VanDerWaalsContact O-N 3.13Å
308A90.8Very high94.7Very high58 Ų5810.8 Ų10.848%0.4797%0.071SC..Hα-helixtrans-64.8-44.617400000112.4G304 L306 T312G304-A308 VanDerWaalsContact O-CB 3.23Å; G304-A308 WeakPolarHBondContact O-CB 3.39Å; G304-A308 PolarHBondContact O-N 3.45Å; L306-A308 VanDerWaalsContact C-N 3.27Å; L306-A308 PolarHBondContact O-N 2.92Å; A308-T312 PolarHBondContact O-OG1 3.48Å
309G89.4Confident94.8Very high9 Ų911 Ų119%0.0937%0.072CC..Hα-helixtrans-74.9-25.5-179.900000114.2L305 L306 S313L305-G309 PolarHBondContact O-N 2.86Å; L306-G309 PolarHBondContact O-N 3.48Å; G309-S313 VanDerWaalsContact O-CB 3.26Å; G309-S313 WeakPolarHBondContact O-CB 3.47Å; G309-S313 PolarHBondContact O-OG 3.24Å
310Q90.3Very high94.9Very high16 Ų1611 Ų118%0.0757%0.072CC..Hα-helixtrans-77.4-63-171.9174.160.25.400113.5S196 L306 S314S196-Q310 PolarHBondContact O-NE2 3.49Å; L306-Q310 WeakPolarHBondContact O-CB 3.43Å; L306-Q310 PolarHBondContact O-N 3.04Å; Q310-S314 VanDerWaalsContact O-CB 3.31Å; Q310-S314 WeakPolarHBondContact O-CB 3.34Å; Q310-S314 PolarHBondContact O-N 3.43Å; Q310-S314 PolarHBondContact O-OG 3.27Å
311H89.4Confident95Very high44 Ų4411 Ų1120%0.2047%0.071CC..Hα-helixtrans-72.8-36.8-169.2-65-62000112.8D228 S314 T315 I482D228-H311 VanDerWaalsContact CG-CE1 3.46Å; D228-H311 IonicContact OD1-CD2 3.01Å; D228-H311 IonicContact OD1-CE1 2.62Å; D228-H311 IonicContact OD1-NE2 3.71Å; D228-H311 PolarHBondContact OD1-NE2 3.41Å; D228-H311 IonicContact OD2-CE1 3.56Å; D228-H311 PolarHBondContact OD2-CE1 3.35Å; D228-H311 IonicContact OD2-NE2 3.43Å; D228-H311 PolarHBondContact OD2-NE2 2.84Å; H311-S314 PolarHBondContact O-OG 3.5Å; H311-T315 WeakPolarHBondContact O-CG2 3.24Å; H311-T315 PolarHBondContact O-N 2.96Å; H311-T315 PolarHBondContact O-OG1 3.4Å; H311-I482 HydrophobicContact CB-CD1 3.27Å
312T96.1Very high95.1Very high41 Ų4110.5 Ų10.525%0.2527%0.069SC..Hα-helixtrans-67.2-46.7-179.559.90000110.9A308 T315 T316 P373A308-T312 PolarHBondContact O-OG1 3.48Å; T312-T315 PolarHBondContact O-OG1 3.37Å; T312-T316 VanDerWaalsContact O-CB 3.29Å; T312-T316 WeakPolarHBondContact O-CB 3.46Å; T312-T316 PolarHBondContact O-N 2.89Å; T312-T316 PolarHBondContact O-OG1 2.66Å; T312-P373 HydrophobicContact CG2-CB 4.23Å; T312-P373 HydrophobicContact CG2-CG 4.01Å
313S98.3Very high95.3Very high1 Ų111 Ų111%0.0077%0.071CC..Hα-helixtrans-71.4-38.4178.9-63.30000113G309 S317 Q452G309-S313 VanDerWaalsContact O-CB 3.26Å; G309-S313 WeakPolarHBondContact O-CB 3.47Å; G309-S313 PolarHBondContact O-OG 3.24Å; S313-S317 WeakPolarHBondContact O-CB 3.33Å; S313-S317 PolarHBondContact O-N 2.9Å; S313-S317 PolarHBondContact O-OG 2.62Å; S313-Q452 VanDerWaalsContact CB-OE1 3.26Å; S313-Q452 PolarHBondContact OG-OE1 3.32Å
314S97.4Very high95.5Very high0 Ų011 Ų110%07%0.072CC..Hα-helixtrans-68.4-45-177.454.10000113.3Q310 H311 S317 A318Q310-S314 VanDerWaalsContact O-CB 3.31Å; Q310-S314 WeakPolarHBondContact O-CB 3.34Å; Q310-S314 PolarHBondContact O-N 3.43Å; Q310-S314 PolarHBondContact O-OG 3.27Å; H311-S314 PolarHBondContact O-OG 3.5Å; S314-S317 PolarHBondContact O-N 3.02Å; S314-A318 WeakPolarHBondContact O-CB 3.47Å; S314-A318 PolarHBondContact O-N 3.34Å
315T97.8Very high95.7Very high2 Ų210.6 Ų10.61%0.0127%0.066CC..Hα-helixtrans-65.2-44.617552.10000112F192 H311 T312 S317 A318 W319 I482 T484F192-T315 HydrophobicContact CD2-CG2 4.4Å; F192-T315 HydrophobicContact CE2-CG2 3.48Å; F192-T315 VanDerWaalsContact CE2-CG2 3.48Å; F192-T315 HydrophobicContact CZ-CG2 3.94Å; H311-T315 WeakPolarHBondContact O-CG2 3.24Å; H311-T315 PolarHBondContact O-N 2.96Å; H311-T315 PolarHBondContact O-OG1 3.4Å; T312-T315 PolarHBondContact O-OG1 3.37Å; T315-S317 PolarHBondContact O-N 2.85Å; T315-A318 PolarHBondContact O-N 3.37Å; T315-W319 PolarHBondContact O-N 3.13Å; T315-I482 HydrophobicContact CG2-CG2 3.75Å; T315-T484 HydrophobicContact CG2-CG2 3.87Å
316T98.8Very high96Very high2 Ų215 Ų151%0.0129%0.087CC..Hα-helixtrans-60.4-46.1176.3-56.20000111.1T312 A318 W319 L320 L364 T367 L368 I453T312-T316 VanDerWaalsContact O-CB 3.29Å; T312-T316 WeakPolarHBondContact O-CB 3.46Å; T312-T316 PolarHBondContact O-N 2.89Å; T312-T316 PolarHBondContact O-OG1 2.66Å; T316-A318 PolarHBondContact O-N 3.21Å; T316-W319 PolarHBondContact O-N 3.38Å; T316-L320 WeakPolarHBondContact O-CB 3.47Å; T316-L320 PolarHBondContact O-N 2.99Å; T316-L364 HydrophobicContact CG2-CD1 3.5Å; T316-T367 HydrophobicContact CG2-CG2 4.01Å; T316-T367 WeakPolarHBondContact O-CG2 3.1Å; T316-L368 HydrophobicContact CG2-CD2 3.65Å; T316-L368 HydrophobicContact CG2-CG 3.9Å; T316-I453 HydrophobicContact CG2-CD1 3.94Å
317S98.9Very high96.4Very high0 Ų018.2 Ų18.20%010%0.104CC..Hα-helixtrans-62.9-42.6179-61.70000111.3S313 S314 T315 L320 G321 W457S313-S317 WeakPolarHBondContact O-CB 3.33Å; S313-S317 PolarHBondContact O-N 2.9Å; S313-S317 PolarHBondContact O-OG 2.62Å; S314-S317 PolarHBondContact O-N 3.02Å; T315-S317 PolarHBondContact O-N 2.85Å; S317-L320 PolarHBondContact O-N 3.28Å; S317-G321 PolarHBondContact O-N 2.97Å; S317-G321 VanDerWaalsContact O-N 3.08Å; S317-W457 VanDerWaalsContact O-CE2 3.27Å; S317-W457 WeakPolarHBondContact O-CZ2 3.43Å; S317-W457 PolarHBondContact O-NE1 2.88Å
318A98.8Very high96.7Very high0 Ų020.4 Ų20.40%011%0.113CC..Hα-helixtrans-62.4-46.5177.600000111.6F192 L195 S314 T315 T316 L320 G321 F322 P485F192-A318 HydrophobicContact CB-CB 4.03Å; F192-A318 HydrophobicContact CD2-CB 3.95Å; F192-A318 HydrophobicContact CG-CB 4.45Å; L195-A318 HydrophobicContact CD1-CB 4.08Å; S314-A318 WeakPolarHBondContact O-CB 3.47Å; S314-A318 PolarHBondContact O-N 3.34Å; T315-A318 PolarHBondContact O-N 3.37Å; T316-A318 PolarHBondContact O-N 3.21Å; A318-L320 PolarHBondContact O-N 3.42Å; A318-G321 PolarHBondContact O-N 2.9Å; A318-G321 VanDerWaalsContact O-N 3.15Å; A318-F322 WeakPolarHBondContact O-CD2 3.47Å; A318-F322 PolarHBondContact O-N 3.28Å; A318-F322 VanDerWaalsContact O-N 3.15Å; A318-P485 HydrophobicContact CB-CG 4.14Å
319W98.9Very high97.1Very high3 Ų320.8 Ų20.81%0.01112%0.116CC..Hα-helixtrans-61-42.6176.7-75.7121.1000112.7T315 T316 G321 F322 F323 T367 R371 F473 P474 I476 P485T315-W319 PolarHBondContact O-N 3.13Å; T316-W319 PolarHBondContact O-N 3.38Å; W319-G321 PolarHBondContact O-N 3.2Å; W319-F322 PolarHBondContact O-N 3.37Å; W319-F323 HydrophobicContact CB-CD2 4.46Å; W319-F323 HydrophobicContact CB-CE2 4.25Å; W319-F323 WeakPolarHBondContact O-CD2 3.34Å; W319-F323 PolarHBondContact O-N 3.2Å; W319-T367 HydrophobicContact CB-CG2 3.77Å; W319-R371 HydrophobicContact CB-CB 4.08Å; W319-R371 HydrophobicContact CB-CG 4.09Å; W319-R371 HydrophobicContact CD2-CB 4.2Å; W319-R371 HydrophobicContact CD2-CG 3.66Å; W319-R371 HydrophobicContact CE3-CG 4.14Å; W319-R371 HydrophobicContact CG-CB 3.68Å; W319-R371 HydrophobicContact CG-CG 3.62Å; W319-F473 HydrophobicContact CE3-CE1 4.31Å; W319-F473 HydrophobicContact CE3-CZ 4.25Å; W319-F473 AromaticContact CZ3-CE1 3.76Å; W319-F473 HydrophobicContact CZ3-CE1 3.76Å; W319-F473 HydrophobicContact CZ3-CZ 4.15Å; W319-P474 HydrophobicContact CH2-CB 4.14Å; W319-P474 WeakPolarHBondContact CH2-O 3.34Å; W319-P474 HydrophobicContact CZ3-CB 3.98Å; W319-P474 WeakPolarHBondContact CZ3-O 3.37Å; W319-I476 HydrophobicContact CH2-CG1 3.99Å; W319-I476 HydrophobicContact CZ2-CG1 3.97Å; W319-P485 HydrophobicContact CD2-CB 4.36Å; W319-P485 HydrophobicContact CE3-CB 4.37Å; W319-P485 HydrophobicContact CH2-CB 3.74Å; W319-P485 VanDerWaalsContact CZ2-CA 3.48Å; W319-P485 HydrophobicContact CZ2-CB 3.73Å; W319-P485 HydrophobicContact CZ3-CB 4.07Å
320L98.9Very high97.5Very high1 Ų120.4 Ų20.41%0.00511%0.112CC..Hα-helixtrans-56.2-42.8174.4174.756.1000110.9T316 S317 A318 F322 F323 L324 L360 C363 T367 F418 I453 W457T316-L320 WeakPolarHBondContact O-CB 3.47Å; T316-L320 PolarHBondContact O-N 2.99Å; S317-L320 PolarHBondContact O-N 3.28Å; A318-L320 PolarHBondContact O-N 3.42Å; L320-F322 PolarHBondContact O-N 2.96Å; L320-F323 PolarHBondContact O-N 2.85Å; L320-L324 HydrophobicContact CD1-CD1 3.81Å; L320-L324 HydrophobicContact CD1-CD2 4.47Å; L320-L324 HydrophobicContact CD1-CG 3.89Å; L320-L324 HydrophobicContact CG-CD1 4.02Å; L320-L324 HydrophobicContact CG-CG 4.48Å; L320-L324 WeakPolarHBondContact O-CG 3.36Å; L320-L324 PolarHBondContact O-N 3.42Å; L320-L360 HydrophobicContact CD2-CD1 4.47Å; L320-C363 HydrophobicContact CD1-CB 3.77Å; L320-T367 HydrophobicContact CB-CG2 4.08Å; L320-F418 HydrophobicContact CD1-CZ 4.48Å; L320-I453 HydrophobicContact CD2-CG2 4.24Å; L320-W457 HydrophobicContact CD2-CB 4.23Å; L320-W457 VanDerWaalsContact CD2-CD1 3.49Å; L320-W457 HydrophobicContact CD2-CD2 4.08Å; L320-W457 HydrophobicContact CD2-CG 3.63Å; L320-W457 HydrophobicContact CG-CD2 4.17Å; L320-W457 HydrophobicContact CG-CG 4.25Å
321G98.8Very high97.9Very high0 Ų019.7 Ų19.70%011%0.108CC..Hα-helixtrans-60.2-43.9176.300000114.2S317 A318 W319 L324 A325 W457S317-G321 PolarHBondContact O-N 2.97Å; S317-G321 VanDerWaalsContact O-N 3.08Å; A318-G321 PolarHBondContact O-N 2.9Å; A318-G321 VanDerWaalsContact O-N 3.15Å; W319-G321 PolarHBondContact O-N 3.2Å; G321-L324 PolarHBondContact O-N 3.42Å; G321-A325 VanDerWaalsContact O-CB 3.24Å; G321-A325 WeakPolarHBondContact O-CB 3.5Å; G321-A325 PolarHBondContact O-N 2.96Å; G321-W457 VanDerWaalsContact N-CZ2 3.3Å
322F98.9Very high98.4Very high0 Ų020.8 Ų20.80%012%0.116CC..Hα-helixtrans-68.9-36.9177.1-73.7-70.4000112.9L191 A318 W319 L320 A325 Q326 L468 F473 P474 P488 I490L191-F322 HydrophobicContact CB-CE2 4.47Å; L191-F322 HydrophobicContact CB-CZ 4.47Å; L191-F322 HydrophobicContact CD2-CE2 4.39Å; A318-F322 WeakPolarHBondContact O-CD2 3.47Å; A318-F322 PolarHBondContact O-N 3.28Å; A318-F322 VanDerWaalsContact O-N 3.15Å; W319-F322 PolarHBondContact O-N 3.37Å; L320-F322 PolarHBondContact O-N 2.96Å; F322-A325 PolarHBondContact O-N 3.14Å; F322-Q326 WeakPolarHBondContact O-CB 3.19Å; F322-Q326 PolarHBondContact O-N 3.49Å; F322-L468 HydrophobicContact CD1-CD2 3.79Å; F322-F473 HydrophobicContact CB-CD2 4.35Å; F322-F473 HydrophobicContact CB-CE2 3.89Å; F322-F473 HydrophobicContact CB-CZ 4.34Å; F322-P474 HydrophobicContact CD1-CG 3.51Å; F322-P474 HydrophobicContact CD2-CG 3.72Å; F322-P474 HydrophobicContact CE1-CG 3.53Å; F322-P474 HydrophobicContact CE2-CG 3.77Å; F322-P474 HydrophobicContact CG-CG 3.63Å; F322-P474 HydrophobicContact CZ-CG 3.69Å; F322-P488 HydrophobicContact CE2-CB 3.7Å; F322-P488 VanDerWaalsContact CZ-C 3.47Å; F322-P488 VanDerWaalsContact CZ-CA 3.49Å; F322-P488 HydrophobicContact CZ-CB 3.82Å; F322-I490 HydrophobicContact CD1-CD1 4.41Å; F322-I490 HydrophobicContact CE1-CB 4.11Å; F322-I490 HydrophobicContact CE1-CD1 4.3Å; F322-I490 HydrophobicContact CE1-CG1 4.18Å; F322-I490 HydrophobicContact CZ-CB 4.22Å
323F98.9Very high98.5Very high10 Ų1024.3 Ų24.34%0.04412%0.124CC..Hα-helixtrans-64-44.6173.9-72.8-57.8000111.8W319 L320 Q326 D327 T367 L370 R371 F418 F473W319-F323 HydrophobicContact CB-CD2 4.46Å; W319-F323 HydrophobicContact CB-CE2 4.25Å; W319-F323 WeakPolarHBondContact O-CD2 3.34Å; W319-F323 PolarHBondContact O-N 3.2Å; L320-F323 PolarHBondContact O-N 2.85Å; F323-Q326 PolarHBondContact O-N 2.85Å; F323-D327 PolarHBondContact O-N 3.08Å; F323-D327 VanDerWaalsContact O-N 3.09Å; F323-T367 HydrophobicContact CD2-CG2 4.26Å; F323-T367 HydrophobicContact CE2-CG2 4.3Å; F323-L370 HydrophobicContact CE1-CD1 4.17Å; F323-L370 HydrophobicContact CE2-CB 4.46Å; F323-L370 HydrophobicContact CZ-CB 4.02Å; F323-L370 HydrophobicContact CZ-CD1 3.96Å; F323-R371 HydrophobicContact CE2-CG 3.94Å; F323-R371 HydrophobicContact CZ-CG 4.07Å; F323-F418 HydrophobicContact CB-CD1 3.94Å; F323-F418 HydrophobicContact CB-CD2 3.76Å; F323-F418 HydrophobicContact CB-CE1 3.82Å; F323-F418 HydrophobicContact CB-CE2 3.66Å; F323-F418 HydrophobicContact CB-CG 3.91Å; F323-F418 HydrophobicContact CB-CZ 3.7Å; F323-F418 HydrophobicContact CD1-CB 3.69Å; F323-F418 HydrophobicContact CD1-CD1 4.38Å; F323-F418 AromaticContact CD1-CD2 3.43Å; F323-F418 HydrophobicContact CD1-CD2 3.43Å; F323-F418 VanDerWaalsContact CD1-CD2 3.43Å; F323-F418 HydrophobicContact CD1-CE2 4.15Å; F323-F418 AromaticContact CD1-CG 3.58Å; F323-F418 HydrophobicContact CD1-CG 3.58Å; F323-F418 AromaticContact CD2-CD2 3.45Å; F323-F418 HydrophobicContact CD2-CD2 3.45Å; F323-F418 VanDerWaalsContact CD2-CD2 3.45Å; F323-F418 AromaticContact CD2-CE2 3.39Å; F323-F418 HydrophobicContact CD2-CE2 3.39Å; F323-F418 HydrophobicContact CD2-CG 4.35Å; F323-F418 HydrophobicContact CD2-CZ 4.24Å; F323-F418 HydrophobicContact CE1-CB 3.94Å; F323-F418 AromaticContact CE1-CD2 3.78Å; F323-F418 HydrophobicContact CE1-CD2 3.78Å; F323-F418 HydrophobicContact CE1-CG 4.13Å; F323-F418 AromaticContact CE2-CD2 3.8Å; F323-F418 HydrophobicContact CE2-CD2 3.8Å; F323-F418 HydrophobicContact CE2-CE2 4.01Å; F323-F418 HydrophobicContact CG-CB 4.34Å; F323-F418 HydrophobicContact CG-CD1 4.27Å; F323-F418 AromaticContact CG-CD2 3.26Å; F323-F418 HydrophobicContact CG-CD2 3.26Å; F323-F418 HydrophobicContact CG-CE1 4.42Å; F323-F418 AromaticContact CG-CE2 3.48Å; F323-F418 HydrophobicContact CG-CE2 3.48Å; F323-F418 VanDerWaalsContact CG-CE2 3.48Å; F323-F418 AromaticContact CG-CG 3.71Å; F323-F418 HydrophobicContact CG-CG 3.71Å; F323-F418 HydrophobicContact CG-CZ 4.08Å; F323-F418 AromaticContact CZ-CD2 3.95Å; F323-F418 HydrophobicContact CZ-CD2 3.95Å; F323-F473 AromaticContact CD1-CE2 3.81Å; F323-F473 HydrophobicContact CD1-CE2 3.81Å; F323-F473 AromaticContact CD1-CZ 3.71Å; F323-F473 HydrophobicContact CD1-CZ 3.71Å; F323-F473 HydrophobicContact CE1-CE1 4.45Å; F323-F473 HydrophobicContact CE1-CE2 4.07Å; F323-F473 AromaticContact CE1-CZ 3.5Å; F323-F473 HydrophobicContact CE1-CZ 3.5Å; F323-F473 HydrophobicContact CG-CE2 4.44Å; F323-F473 HydrophobicContact CG-CZ 4.39Å; F323-F473 HydrophobicContact CZ-CZ 4.03Å
324L98.8Very high98.5Very high1 Ų124.2 Ų24.21%0.00512%0.124CC..Hα-helixtrans-68.3-32.9176-66.2175.9000112.6L320 G321 Q326 D327 L330 Q331 W457 L461L320-L324 HydrophobicContact CD1-CD1 3.81Å; L320-L324 HydrophobicContact CD1-CD2 4.47Å; L320-L324 HydrophobicContact CD1-CG 3.89Å; L320-L324 HydrophobicContact CG-CD1 4.02Å; L320-L324 HydrophobicContact CG-CG 4.48Å; L320-L324 WeakPolarHBondContact O-CG 3.36Å; L320-L324 PolarHBondContact O-N 3.42Å; G321-L324 PolarHBondContact O-N 3.42Å; L324-Q326 VanDerWaalsContact C-N 3.33Å; L324-D327 CarbonylContact O-C 3.5Å; L324-L330 HydrophobicContact CD2-CD2 4.14Å; L324-L330 HydrophobicContact CD2-CG 4.1Å; L324-Q331 HydrophobicContact CB-CB 4.37Å; L324-Q331 HydrophobicContact CB-CG 4.28Å; L324-Q331 WeakPolarHBondContact O-CB 3.41Å; L324-Q331 PolarHBondContact O-NE2 3.29Å; L324-W457 HydrophobicContact CD1-CE3 4.03Å; L324-W457 HydrophobicContact CD1-CZ3 4.32Å; L324-L461 HydrophobicContact CD1-CD2 4.34Å
325A98.7Very high98.6Very high5 Ų525.3 Ų25.34%0.04113%0.128CC..Hα-helixtrans-71.9-29176.200000112.9G321 F322 F466 L468 I490G321-A325 VanDerWaalsContact O-CB 3.24Å; G321-A325 WeakPolarHBondContact O-CB 3.5Å; G321-A325 PolarHBondContact O-N 2.96Å; F322-A325 PolarHBondContact O-N 3.14Å; A325-F466 HydrophobicContact CB-CB 4.11Å; A325-L468 HydrophobicContact CB-CD2 3.87Å; A325-L468 HydrophobicContact CB-CG 4.33Å; A325-I490 HydrophobicContact CB-CD1 3.92Å; A325-I490 HydrophobicContact CB-CG1 4.36Å
326Q98.4Very high98.6Very high112 Ų11227.7 Ų27.752%0.52315%0.148SC..Hα-helixtrans-72.7-42.4174-171.8174.433.400111.9F322 F323 L324 L468 F473F322-Q326 WeakPolarHBondContact O-CB 3.19Å; F322-Q326 PolarHBondContact O-N 3.49Å; F323-Q326 PolarHBondContact O-N 2.85Å; L324-Q326 VanDerWaalsContact C-N 3.33Å; Q326-L468 HydrophobicContact CB-CD1 3.96Å; Q326-L468 HydrophobicContact CB-CG 4.49Å; Q326-L468 HydrophobicContact CG-CD1 4.11Å; Q326-F473 HydrophobicContact CB-CD2 4.25Å; Q326-F473 HydrophobicContact CG-CD2 4.46Å
327D98.2Very high98.6Very high68 Ų6829 Ų2936%0.36415%0.154SC..  trans-105.890.8178-171.5-16.8000111.6F323 L324 A329 L330 Q331F323-D327 PolarHBondContact O-N 3.08Å; F323-D327 VanDerWaalsContact O-N 3.09Å; L324-D327 CarbonylContact O-C 3.5Å; D327-A329 PolarHBondContact O-N 3.13Å; D327-A329 PolarHBondContact OD1-N 2.88Å; D327-L330 HydrophobicContact CB-CB 3.89Å; D327-L330 PolarHBondContact O-N 3.14Å; D327-L330 PolarHBondContact OD1-N 2.92Å; D327-L330 WeakPolarHBondContact OD2-CB 3.46Å; D327-Q331 PolarHBondContact O-N 3.45Å
328K97.1Very high98.6Very high56 Ų5629 Ų2924%0.24315%0.154CC..Hα-helixtrans-62.2-39.3179.5-70.4-56.9-157.3147.70114L330 Q331 D332 E465 F466 E467K328-L330 VanDerWaalsContact C-N 3.29Å; K328-L330 PolarHBondContact O-N 3.1Å; K328-Q331 WeakPolarHBondContact O-CB 3.37Å; K328-Q331 PolarHBondContact O-N 3.22Å; K328-D332 PolarHBondContact O-N 2.71Å; K328-E465 IonicContact NZ-OE1 3.22Å; K328-E465 PolarHBondContact NZ-OE1 3.45Å; K328-F466 WeakPolarHBondContact CE-O 3.43Å; K328-F466 PolarHBondContact NZ-O 3.13Å; K328-E467 IonicContact NZ-OE1 2.68Å
329A98.3Very high98.5Very high65 Ų6530.8 Ų30.854%0.53716%0.162SC..Hα-helixtrans-64.9-39.5179.600000110.6D327 R333D327-A329 PolarHBondContact O-N 3.13Å; D327-A329 PolarHBondContact OD1-N 2.88Å; A329-R333 VanDerWaalsContact O-CG 3.25Å; A329-R333 WeakPolarHBondContact O-CG 3.46Å; A329-R333 PolarHBondContact O-N 3.49Å
330L98.7Very high98.5Very high2 Ų234.7 Ų34.71%0.0120%0.195CC..Hα-helixtrans-65.9-43173.4-178.763.5000112.2L324 D327 K328 D332 R333 C334 L359 F418 P420L324-L330 HydrophobicContact CD2-CD2 4.14Å; L324-L330 HydrophobicContact CD2-CG 4.1Å; D327-L330 HydrophobicContact CB-CB 3.89Å; D327-L330 PolarHBondContact O-N 3.14Å; D327-L330 PolarHBondContact OD1-N 2.92Å; D327-L330 WeakPolarHBondContact OD2-CB 3.46Å; K328-L330 VanDerWaalsContact C-N 3.29Å; K328-L330 PolarHBondContact O-N 3.1Å; L330-D332 VanDerWaalsContact C-N 3.34Å; L330-D332 PolarHBondContact O-N 2.85Å; L330-R333 PolarHBondContact O-N 3.08Å; L330-C334 PolarHBondContact O-N 3.17Å; L330-C334 PolarHBondContact O-SG 3.16Å; L330-C334 VanDerWaalsContact O-SG 3.39Å; L330-L359 HydrophobicContact CD1-CD1 3.9Å; L330-L359 HydrophobicContact CD1-CD2 4.21Å; L330-L359 HydrophobicContact CD1-CG 4.29Å; L330-F418 HydrophobicContact CD2-CD1 4.04Å; L330-F418 HydrophobicContact CD2-CE1 3.61Å; L330-P420 HydrophobicContact CD1-CG 4.27Å; L330-P420 HydrophobicContact CD2-CG 3.79Å
331Q98.8Very high98.5Very high0 Ų036.9 Ų36.90%021%0.208CC..Hα-helixtrans-58.3-44.8176.5-166.7-176.3141.300112.3L324 D327 K328 C334 Y335 L461 F466L324-Q331 HydrophobicContact CB-CB 4.37Å; L324-Q331 HydrophobicContact CB-CG 4.28Å; L324-Q331 WeakPolarHBondContact O-CB 3.41Å; L324-Q331 PolarHBondContact O-NE2 3.29Å; D327-Q331 PolarHBondContact O-N 3.45Å; K328-Q331 WeakPolarHBondContact O-CB 3.37Å; K328-Q331 PolarHBondContact O-N 3.22Å; Q331-C334 WeakPolarHBondContact O-CB 3.25Å; Q331-C334 PolarHBondContact O-N 3.15Å; Q331-Y335 PolarHBondContact O-N 2.86Å; Q331-L461 HydrophobicContact CG-CD2 3.67Å; Q331-F466 PolarHBondContact NE2-O 3.32Å
332D98.5Very high98.4Very high68 Ų6837.4 Ų37.436%0.36421%0.212SC..Hα-helixtrans-69-33.7178.4-73.2-28.8000112.4K328 L330 Y335 A336 R495K328-D332 PolarHBondContact O-N 2.71Å; L330-D332 VanDerWaalsContact C-N 3.34Å; L330-D332 PolarHBondContact O-N 2.85Å; D332-Y335 PolarHBondContact O-N 3.35Å; D332-A336 WeakPolarHBondContact O-CB 3.43Å; D332-A336 PolarHBondContact O-N 2.97Å; D332-R495 IonicContact OD1-CZ 3.57Å; D332-R495 IonicContact OD1-NH1 2.71Å; D332-R495 PolarHBondContact OD1-NH1 3.3Å; D332-R495 IonicContact OD1-NH2 2.86Å; D332-R495 PolarHBondContact OD1-NH2 3.33Å
333R98.6Very high98.3Very high114 Ų11438.6 Ų38.643%0.4322%0.224SC..Hα-helixtrans-65-39.9170.4-73.6168.560.2-149.5-4.5112.2A329 L330 Y335 A336 E337 L359 E421A329-R333 VanDerWaalsContact O-CG 3.25Å; A329-R333 WeakPolarHBondContact O-CG 3.46Å; A329-R333 PolarHBondContact O-N 3.49Å; L330-R333 PolarHBondContact O-N 3.08Å; R333-Y335 VanDerWaalsContact C-N 3.32Å; R333-A336 PolarHBondContact O-N 3.36Å; R333-E337 PolarHBondContact O-N 2.99Å; R333-L359 HydrophobicContact CB-CD2 3.65Å; R333-E421 IonicContact CZ-OE1 2.8Å; R333-E421 VanDerWaalsContact CZ-OE1 3.23Å; R333-E421 IonicContact NH1-OE1 2.7Å; R333-E421 PolarHBondContact NH1-OE1 3.39Å; R333-E421 IonicContact NH2-OE1 3.88Å; R333-E421 PolarHBondContact NH2-OE1 2.92Å
334C98.7Very high98.1Very high0 Ų044.5 Ų44.50%025%0.252CS..Hα-helixtrans-63.6-38.6173.5-70.80000111.5L330 Q331 E337 Q338 L461L330-C334 PolarHBondContact O-N 3.17Å; L330-C334 PolarHBondContact O-SG 3.16Å; L330-C334 VanDerWaalsContact O-SG 3.39Å; Q331-C334 WeakPolarHBondContact O-CB 3.25Å; Q331-C334 PolarHBondContact O-N 3.15Å; C334-E337 WeakPolarHBondContact O-CB 3.36Å; C334-E337 PolarHBondContact O-N 3.42Å; C334-Q338 WeakPolarHBondContact O-CG 3.48Å; C334-Q338 PolarHBondContact O-N 3.32Å; C334-L461 HydrophobicContact CB-CD1 3.75Å
335Y98.6Very high97.9Very high22 Ų2250.7 Ų50.79%0.08629%0.285CS..Hα-helixtrans-67-42.9173.6177.9-108.6000112.3Q331 D332 R333 E337 Q338 K339 L346 L461 R495Q331-Y335 PolarHBondContact O-N 2.86Å; D332-Y335 PolarHBondContact O-N 3.35Å; R333-Y335 VanDerWaalsContact C-N 3.32Å; Y335-E337 VanDerWaalsContact C-N 3.27Å; Y335-E337 PolarHBondContact O-N 2.88Å; Y335-Q338 VanDerWaalsContact O-CB 3.29Å; Y335-Q338 WeakPolarHBondContact O-CB 3.36Å; Y335-Q338 PolarHBondContact O-N 3.2Å; Y335-Q338 VanDerWaalsContact O-N 3.08Å; Y335-K339 HydrophobicContact CE1-CD 4.02Å; Y335-K339 PolarHBondContact O-N 2.86Å; Y335-K339 WeakPolarHBondContact OH-CE 3.19Å; Y335-L346 HydrophobicContact CE2-CD1 3.97Å; Y335-L461 VanDerWaalsContact CD2-O 3.3Å; Y335-L461 WeakPolarHBondContact CD2-O 3.42Å; Y335-R495 VanDerWaalsContact CD2-CD 3.43Å; Y335-R495 HydrophobicContact CE2-CG 4.46Å; Y335-R495 VanDerWaalsContact CZ-CD 3.42Å
336A98.5Very high97.8Very high52 Ų5251.8 Ų51.843%0.4329%0.29SS..Hα-helixtrans-61.3-36.7174.700000112D332 R333 Q338 K339 A340D332-A336 WeakPolarHBondContact O-CB 3.43Å; D332-A336 PolarHBondContact O-N 2.97Å; R333-A336 PolarHBondContact O-N 3.36Å; A336-Q338 VanDerWaalsContact C-N 3.31Å; A336-Q338 PolarHBondContact O-N 3.46Å; A336-K339 PolarHBondContact O-N 2.75Å; A336-A340 WeakPolarHBondContact O-CB 3.43Å; A336-A340 PolarHBondContact O-N 2.99Å
337E98.6Very high97.7Very high30 Ų3048.3 Ų48.314%0.1428%0.277CS..Hα-helixtrans-59.9-39.6172.3-179.8175.9-105.800111.9R333 C334 Y335 K339 A340 V341 L357 N358 L359 L360R333-E337 PolarHBondContact O-N 2.99Å; C334-E337 WeakPolarHBondContact O-CB 3.36Å; C334-E337 PolarHBondContact O-N 3.42Å; Y335-E337 VanDerWaalsContact C-N 3.27Å; Y335-E337 PolarHBondContact O-N 2.88Å; E337-K339 VanDerWaalsContact C-N 3.34Å; E337-K339 PolarHBondContact O-N 2.78Å; E337-A340 PolarHBondContact O-N 3.15Å; E337-V341 HydrophobicContact CG-CG2 4.17Å; E337-V341 WeakPolarHBondContact O-CB 3.44Å; E337-V341 WeakPolarHBondContact O-CG2 3.16Å; E337-V341 PolarHBondContact O-N 3Å; E337-L357 HydrophobicContact CG-CD2 3.87Å; E337-L357 WeakPolarHBondContact OE2-CA 3.27Å; E337-N358 PolarHBondContact OE1-N 3.48Å; E337-N358 VanDerWaalsContact OE1-N 3.14Å; E337-L359 WeakPolarHBondContact OE1-CB 3.4Å; E337-L359 PolarHBondContact OE1-N 3.23Å; E337-L359 WeakPolarHBondContact OE2-CB 3.35Å; E337-L359 PolarHBondContact OE2-N 2.88Å; E337-L360 PolarHBondContact OE2-N 3.36Å
338Q98.5Very high97.7Very high0 Ų050 Ų500%029%0.291CS..Hα-helixtrans-58-47.2175.2-60.4-67.1-51.900111.4C334 Y335 A336 C342 L346 S458C334-Q338 WeakPolarHBondContact O-CG 3.48Å; C334-Q338 PolarHBondContact O-N 3.32Å; Y335-Q338 VanDerWaalsContact O-CB 3.29Å; Y335-Q338 WeakPolarHBondContact O-CB 3.36Å; Y335-Q338 PolarHBondContact O-N 3.2Å; Y335-Q338 VanDerWaalsContact O-N 3.08Å; A336-Q338 VanDerWaalsContact C-N 3.31Å; A336-Q338 PolarHBondContact O-N 3.46Å; Q338-C342 WeakPolarHBondContact O-CB 3.45Å; Q338-C342 PolarHBondContact O-N 2.97Å; Q338-L346 HydrophobicContact CB-CD2 3.86Å; Q338-S458 PolarHBondContact NE2-OG 3.38Å; Q338-S458 VanDerWaalsContact OE1-CB 3.31Å; Q338-S458 PolarHBondContact OE1-OG 3.45Å
339K98.1Very high97.7Very high37 Ų3747.6 Ų47.616%0.16128%0.281CS..Hα-helixtrans-65.7-43.1178.8-71.5-177.1156.9-139.50112Y335 A336 E337 V341 G343 E344 L346Y335-K339 HydrophobicContact CE1-CD 4.02Å; Y335-K339 PolarHBondContact O-N 2.86Å; Y335-K339 WeakPolarHBondContact OH-CE 3.19Å; A336-K339 PolarHBondContact O-N 2.75Å; E337-K339 VanDerWaalsContact C-N 3.34Å; E337-K339 PolarHBondContact O-N 2.78Å; K339-V341 PolarHBondContact O-N 3.16Å; K339-G343 CarbonylContact O-C 3.5Å; K339-G343 VanDerWaalsContact O-C 3.26Å; K339-G343 VanDerWaalsContact O-CA 3.29Å; K339-G343 WeakPolarHBondContact O-CA 3.17Å; K339-G343 PolarHBondContact O-N 3.19Å; K339-E344 WeakPolarHBondContact CD-OE2 3.18Å; K339-E344 WeakPolarHBondContact CE-OE2 3.43Å; K339-E344 IonicContact NZ-OE2 3.18Å; K339-E344 PolarHBondContact NZ-OE2 2.97Å; K339-L346 HydrophobicContact CG-CD1 4.36Å; K339-L346 HydrophobicContact CG-CD2 3.87Å; K339-L346 HydrophobicContact CG-CG 4.2Å
340A98.2Very high97.5Very high86 Ų8647.2 Ų47.271%0.71127%0.27SS*.Hα-helixtrans-64.5-37.5-179.100000113A336 E337A336-A340 WeakPolarHBondContact O-CB 3.43Å; A336-A340 PolarHBondContact O-N 2.99Å; E337-A340 PolarHBondContact O-N 3.15Å
341V98.1Very high97.4Very high47 Ų4747.9 Ų47.929%0.28527%0.273SS..Hα-helixtrans-88.6-41.6-177.8173.40000112.2E337 K339 Q353 D356 L357E337-V341 HydrophobicContact CG-CG2 4.17Å; E337-V341 WeakPolarHBondContact O-CB 3.44Å; E337-V341 WeakPolarHBondContact O-CG2 3.16Å; E337-V341 PolarHBondContact O-N 3Å; K339-V341 PolarHBondContact O-N 3.16Å; V341-Q353 HydrophobicContact CG1-CB 4.23Å; V341-D356 HydrophobicContact CG1-CB 3.75Å; V341-D356 HydrophobicContact CG2-CB 4.32Å; V341-L357 HydrophobicContact CB-CD2 3.92Å; V341-L357 HydrophobicContact CG1-CD2 4.1Å; V341-L357 HydrophobicContact CG2-CD2 4.09Å
342C97.3Very high97.2Very high11 Ų1151 Ų517%0.07429%0.29CS..Hα-helixtrans-95.9-18.8-171.9-56.40000113.9Q338 P347 Q353 R462Q338-C342 WeakPolarHBondContact O-CB 3.45Å; Q338-C342 PolarHBondContact O-N 2.97Å; C342-P347 WeakPolarHBondContact O-CD 3.49Å; C342-P347 VanDerWaalsContact O-CG 3.25Å; C342-P347 WeakPolarHBondContact O-CG 3.43Å; C342-Q353 PolarHBondContact SG-OE1 3.27Å; C342-R462 PolarHBondContact SG-NH2 3Å
343G96.5Very high97Very high25 Ų2549.5 Ų49.526%0.25828%0.281SS..  trans108153.7-170.900000112.8K339 D345 L346K339-G343 CarbonylContact O-C 3.5Å; K339-G343 VanDerWaalsContact O-C 3.26Å; K339-G343 VanDerWaalsContact O-CA 3.29Å; K339-G343 WeakPolarHBondContact O-CA 3.17Å; K339-G343 PolarHBondContact O-N 3.19Å; G343-D345 VanDerWaalsContact C-N 3.26Å; G343-D345 PolarHBondContact O-N 3.35Å; G343-L346 PolarHBondContact O-N 2.84Å
344E94.9Very high96.9Very high134 Ų13444.4 Ų44.463%0.62626%0.262SS*.THydrogen-bonded Turntrans-63.1-30-178.2-79.2-62.3149.800113.6K339 L346K339-E344 WeakPolarHBondContact CD-OE2 3.18Å; K339-E344 WeakPolarHBondContact CE-OE2 3.43Å; K339-E344 IonicContact NZ-OE2 3.18Å; K339-E344 PolarHBondContact NZ-OE2 2.97Å; E344-L346 PolarHBondContact O-N 3.31Å
345D94.6Very high96.7Very high131 Ų13149.1 Ų49.170%0.70128%0.283SS*.THydrogen-bonded Turntrans-77.6-6.7176.862.5-36000113.3G343G343-D345 VanDerWaalsContact C-N 3.26Å; G343-D345 PolarHBondContact O-N 3.35Å
346L96.4Very high96.6Very high27 Ų2752.6 Ų52.614%0.14130%0.303CS..  trans48.861.3178.1-65170.1000112.4Y335 Q338 K339 G343 E344 R462Y335-L346 HydrophobicContact CE2-CD1 3.97Å; Q338-L346 HydrophobicContact CB-CD2 3.86Å; K339-L346 HydrophobicContact CG-CD1 4.36Å; K339-L346 HydrophobicContact CG-CD2 3.87Å; K339-L346 HydrophobicContact CG-CG 4.2Å; G343-L346 PolarHBondContact O-N 2.84Å; E344-L346 PolarHBondContact O-N 3.31Å; L346-R462 HydrophobicContact CD1-CG 4.17Å; L346-R462 HydrophobicContact CD2-CG 4.39Å; L346-R462 PolarHBondContact O-NH1 3.34Å
347P96.9Very high96.6Very high40 Ų4050.1 Ų50.126%0.2628%0.282SS..PPolyproline II helixtrans-63167.5-179.830.6-37000111.4C342 L349 R462C342-P347 WeakPolarHBondContact O-CD 3.49Å; C342-P347 VanDerWaalsContact O-CG 3.25Å; C342-P347 WeakPolarHBondContact O-CG 3.43Å; P347-L349 PolarHBondContact O-N 2.78Å; P347-R462 PolarHBondContact O-NH1 3.16Å
348P97.8Very high96.6Very high102 Ų10252.7 Ų52.766%0.66230%0.297SS*.SBendtrans-47138.9176.2-28.735.7000112.5
349L97.7Very high96.6Very high6 Ų653.1 Ų53.13%0.03130%0.299CS..PPolyproline II helixtrans-63.9139.4-176.9-77.3163.4000111.6V169 E173 P347 L354 T455V169-L349 HydrophobicContact CG1-CB 3.71Å; V169-L349 WeakPolarHBondContact CG1-O 3.33Å; E173-L349 HydrophobicContact CG-CD1 4.46Å; E173-L349 WeakPolarHBondContact OE1-CG 3.42Å; E173-L349 PolarHBondContact OE1-N 3.32Å; E173-L349 VanDerWaalsContact OE1-N 3.11Å; E173-L349 PolarHBondContact OE2-N 2.93Å; E173-L349 VanDerWaalsContact OE2-N 3.08Å; P347-L349 PolarHBondContact O-N 2.78Å; L349-L354 HydrophobicContact CD2-CD2 4.22Å; L349-T455 HydrophobicContact CD1-CG2 3.99Å
350D94.1Very high96.6Very high57 Ų5751.4 Ų51.431%0.30529%0.291SS..  trans-118.2152.7170.6179.564.9000112.1D352 Q353 L354D350-D352 VanDerWaalsContact C-N 3.32Å; D350-D352 PolarHBondContact O-N 3.18Å; D350-D352 WeakPolarHBondContact OD2-CB 3.32Å; D350-D352 PolarHBondContact OD2-N 2.92Å; D350-Q353 HydrophobicContact CB-CG 4.24Å; D350-Q353 VanDerWaalsContact N-OE1 3.08Å; D350-Q353 WeakPolarHBondContact O-CB 3.34Å; D350-Q353 PolarHBondContact O-N 3.02Å; D350-L354 PolarHBondContact O-N 2.88Å
351F95.9Very high96.6Very high17 Ų1750.8 Ų50.88%0.07527%0.274CS..Hα-helixtrans-61.9-35.6179.9177.1-99.2000113.6I162 F165 K166 V169 L354 V451I162-F351 HydrophobicContact CB-CE1 4.45Å; I162-F351 HydrophobicContact CG1-CE1 4.27Å; I162-F351 HydrophobicContact CG1-CZ 4.23Å; I162-F351 HydrophobicContact CG2-CD1 4.22Å; I162-F351 HydrophobicContact CG2-CE1 3.67Å; I162-F351 HydrophobicContact CG2-CZ 4.31Å; F165-F351 HydrophobicContact CB-CD2 3.68Å; F165-F351 HydrophobicContact CB-CE2 3.44Å; F165-F351 VanDerWaalsContact CB-CE2 3.44Å; F165-F351 HydrophobicContact CB-CZ 4.14Å; F165-F351 HydrophobicContact CD2-CE2 4.06Å; F165-F351 HydrophobicContact CD2-CZ 4.26Å; F165-F351 HydrophobicContact CG-CE2 4.13Å; K166-F351 HydrophobicContact CB-CB 4.45Å; K166-F351 HydrophobicContact CG-CB 3.79Å; K166-F351 HydrophobicContact CG-CD1 4.1Å; K166-F351 HydrophobicContact CG-CG 4.07Å; V169-F351 HydrophobicContact CG2-CB 4.05Å; V169-F351 HydrophobicContact CG2-CD2 4.28Å; F351-L354 PolarHBondContact O-N 3.3Å; F351-V451 HydrophobicContact CD2-CG2 4.09Å; F351-V451 HydrophobicContact CE2-CG2 3.65Å
352D94.8Very high96.6Very high64 Ų6450.8 Ų50.834%0.34227%0.269SS..Hα-helixtrans-71.3-37.5180-68.5-41.1000110.4K166 D350 L354 K355K166-D352 IonicContact NZ-OD2 2.71Å; K166-D352 PolarHBondContact NZ-OD2 2.88Å; D350-D352 VanDerWaalsContact C-N 3.32Å; D350-D352 PolarHBondContact O-N 3.18Å; D350-D352 WeakPolarHBondContact OD2-CB 3.32Å; D350-D352 PolarHBondContact OD2-N 2.92Å; D352-L354 VanDerWaalsContact C-N 3.29Å; D352-L354 PolarHBondContact O-N 3.15Å; D352-K355 WeakPolarHBondContact O-CB 3.37Å; D352-K355 PolarHBondContact O-N 3.04Å; D352-K355 VanDerWaalsContact O-N 3.12Å; D352-K355 IonicContact OD1-NZ 2.68Å; D352-K355 PolarHBondContact OD1-NZ 3.49Å
353Q95.3Very high96.7Very high37 Ų3750.2 Ų50.217%0.17327%0.265CS..Hα-helixtrans-59.4-38.9171.4-64.9173.5-21.800112.2V341 C342 D350 K355 D356 L357V341-Q353 HydrophobicContact CG1-CB 4.23Å; C342-Q353 PolarHBondContact SG-OE1 3.27Å; D350-Q353 HydrophobicContact CB-CG 4.24Å; D350-Q353 VanDerWaalsContact N-OE1 3.08Å; D350-Q353 WeakPolarHBondContact O-CB 3.34Å; D350-Q353 PolarHBondContact O-N 3.02Å; Q353-K355 PolarHBondContact O-N 3.44Å; Q353-K355 VanDerWaalsContact O-N 3.14Å; Q353-D356 PolarHBondContact O-N 3.35Å; Q353-L357 PolarHBondContact O-N 2.92Å
354L95.9Very high96.8Very high8 Ų849.1 Ų49.14%0.04225%0.253CS..Hα-helixtrans-57.8-30.1178.7-67.4-174.5000112.3V169 L349 D350 F351 D352 D356 L357 K454 T455V169-L354 HydrophobicContact CG1-CD1 4.4Å; V169-L354 HydrophobicContact CG2-CD1 3.52Å; V169-L354 HydrophobicContact CG2-CG 4.46Å; L349-L354 HydrophobicContact CD2-CD2 4.22Å; D350-L354 PolarHBondContact O-N 2.88Å; F351-L354 PolarHBondContact O-N 3.3Å; D352-L354 VanDerWaalsContact C-N 3.29Å; D352-L354 PolarHBondContact O-N 3.15Å; L354-D356 VanDerWaalsContact C-N 3.27Å; L354-D356 PolarHBondContact O-N 3.43Å; L354-L357 HydrophobicContact CD2-CD1 3.8Å; L354-K454 HydrophobicContact CD2-CB 4.28Å; L354-K454 VanDerWaalsContact O-CE 3.25Å; L354-K454 WeakPolarHBondContact O-CE 3.17Å; L354-K454 PolarHBondContact O-NZ 3.35Å; L354-T455 WeakPolarHBondContact CD1-OG1 3.28Å
355K94.3Very high97Very high99 Ų9944.8 Ų44.843%0.4323%0.232SC..Hα-helixtrans-68.3-30.2178.3-61.6170-175.5160.20112.2D352 Q353D352-K355 WeakPolarHBondContact O-CB 3.37Å; D352-K355 PolarHBondContact O-N 3.04Å; D352-K355 VanDerWaalsContact O-N 3.12Å; D352-K355 IonicContact OD1-NZ 2.68Å; D352-K355 PolarHBondContact OD1-NZ 3.49Å; Q353-K355 PolarHBondContact O-N 3.44Å; Q353-K355 VanDerWaalsContact O-N 3.14Å
356D97.1Very high97.2Very high95 Ų9538.6 Ų38.651%0.50820%0.199SC..Hα-helixtrans-88.6-10.4-175.2-63-34.5000113.1V341 Q353 L354 N358V341-D356 HydrophobicContact CG1-CB 3.75Å; V341-D356 HydrophobicContact CG2-CB 4.32Å; Q353-D356 PolarHBondContact O-N 3.35Å; L354-D356 VanDerWaalsContact C-N 3.27Å; L354-D356 PolarHBondContact O-N 3.43Å; D356-N358 PolarHBondContact O-N 2.93Å; D356-N358 PolarHBondContact O-ND2 3.11Å
357L98.1Very high97.3Very high0 Ų037.3 Ų37.30%019%0.192CC..  trans-74.569.2171.6-60.1175.1000111.3E337 V341 Q353 L354 L360 E361 K454 S458E337-L357 HydrophobicContact CG-CD2 3.87Å; E337-L357 WeakPolarHBondContact OE2-CA 3.27Å; V341-L357 HydrophobicContact CB-CD2 3.92Å; V341-L357 HydrophobicContact CG1-CD2 4.1Å; V341-L357 HydrophobicContact CG2-CD2 4.09Å; Q353-L357 PolarHBondContact O-N 2.92Å; L354-L357 HydrophobicContact CD2-CD1 3.8Å; L357-L360 HydrophobicContact CB-CB 4.26Å; L357-L360 HydrophobicContact CD1-CD2 4.31Å; L357-E361 WeakPolarHBondContact O-CB 3.35Å; L357-E361 PolarHBondContact O-N 2.85Å; L357-K454 WeakPolarHBondContact O-CE 3.34Å; L357-K454 PolarHBondContact O-NZ 3.23Å; L357-K454 VanDerWaalsContact O-NZ 3.07Å; L357-S458 VanDerWaalsContact CD1-OG 3.26Å; L357-S458 WeakPolarHBondContact CD1-OG 3.42Å
358N97.9Very high97.3Very high84 Ų8435.7 Ų35.745%0.44918%0.182SC..Hα-helixtrans-72.8-34.4-171-73.3-61.3000113.6E337 D356 R362E337-N358 PolarHBondContact OE1-N 3.48Å; E337-N358 VanDerWaalsContact OE1-N 3.14Å; D356-N358 PolarHBondContact O-N 2.93Å; D356-N358 PolarHBondContact O-ND2 3.11Å; N358-R362 VanDerWaalsContact O-CG 3.3Å; N358-R362 WeakPolarHBondContact O-CG 3.49Å; N358-R362 PolarHBondContact O-N 3.47Å; N358-R362 VanDerWaalsContact O-N 3.09Å; N358-R362 PolarHBondContact O-NE 3.07Å
359L98.6Very high97.4Very high8 Ų830.8 Ų30.84%0.04215%0.15CC..Hα-helixtrans-71.6-46.8175.5-178.361.4000110.3L330 R333 E337 E361 R362 C363 P420L330-L359 HydrophobicContact CD1-CD1 3.9Å; L330-L359 HydrophobicContact CD1-CD2 4.21Å; L330-L359 HydrophobicContact CD1-CG 4.29Å; R333-L359 HydrophobicContact CB-CD2 3.65Å; E337-L359 WeakPolarHBondContact OE1-CB 3.4Å; E337-L359 PolarHBondContact OE1-N 3.23Å; E337-L359 WeakPolarHBondContact OE2-CB 3.35Å; E337-L359 PolarHBondContact OE2-N 2.88Å; L359-E361 VanDerWaalsContact C-N 3.26Å; L359-E361 PolarHBondContact O-N 2.98Å; L359-R362 PolarHBondContact O-N 2.93Å; L359-R362 VanDerWaalsContact O-N 3.15Å; L359-C363 PolarHBondContact O-N 3.21Å; L359-C363 PolarHBondContact O-SG 3.49Å; L359-P420 HydrophobicContact CD1-CB 4.35Å
360L98.8Very high97.4Very high1 Ų130.6 Ų30.61%0.00515%0.149CC..Hα-helixtrans-59.8-39.5175-177.660.8000111.4L320 E337 L357 C363 L364 K454 W457 S458 L461L320-L360 HydrophobicContact CD2-CD1 4.47Å; E337-L360 PolarHBondContact OE2-N 3.36Å; L357-L360 HydrophobicContact CB-CB 4.26Å; L357-L360 HydrophobicContact CD1-CD2 4.31Å; L360-C363 WeakPolarHBondContact O-CB 3.13Å; L360-C363 PolarHBondContact O-N 3.29Å; L360-L364 PolarHBondContact O-N 2.87Å; L360-K454 HydrophobicContact CD2-CB 4.28Å; L360-K454 HydrophobicContact CD2-CG 4.45Å; L360-W457 HydrophobicContact CD1-CB 4.18Å; L360-S458 VanDerWaalsContact CD2-OG 3.29Å; L360-S458 WeakPolarHBondContact CD2-OG 3.49Å; L360-L461 HydrophobicContact CD1-CD1 4.25Å
361E98.3Very high97.6Very high73 Ų7329.7 Ų29.734%0.34114%0.141SC..Hα-helixtrans-59.3-46.8173.5-169.7157.9117.600112.7L357 L359 C363 L364 K365 Y450 K454L357-E361 WeakPolarHBondContact O-CB 3.35Å; L357-E361 PolarHBondContact O-N 2.85Å; L359-E361 VanDerWaalsContact C-N 3.26Å; L359-E361 PolarHBondContact O-N 2.98Å; E361-C363 VanDerWaalsContact C-N 3.32Å; E361-C363 PolarHBondContact O-N 3.48Å; E361-L364 WeakPolarHBondContact O-CB 3.21Å; E361-L364 PolarHBondContact O-N 3.36Å; E361-K365 WeakPolarHBondContact O-CB 3.47Å; E361-K365 PolarHBondContact O-N 2.92Å; E361-Y450 HydrophobicContact CG-CD1 4.28Å; E361-Y450 HydrophobicContact CG-CE1 3.96Å; E361-K454 IonicContact OE2-NZ 3.42Å; E361-K454 PolarHBondContact OE2-NZ 2.96Å
362R98.3Very high97.7Very high47 Ų4729.1 Ų29.118%0.17714%0.139CC..Hα-helixtrans-66.5-33.8177.6-74.5178-69.5165.6-4.7112.2N358 L359 L364 K365 E366 P420 Y423N358-R362 VanDerWaalsContact O-CG 3.3Å; N358-R362 WeakPolarHBondContact O-CG 3.49Å; N358-R362 PolarHBondContact O-N 3.47Å; N358-R362 VanDerWaalsContact O-N 3.09Å; N358-R362 PolarHBondContact O-NE 3.07Å; L359-R362 PolarHBondContact O-N 2.93Å; L359-R362 VanDerWaalsContact O-N 3.15Å; R362-L364 VanDerWaalsContact C-N 3.35Å; R362-K365 PolarHBondContact O-N 3.29Å; R362-E366 WeakPolarHBondContact O-CB 3.39Å; R362-E366 PolarHBondContact O-N 2.94Å; R362-P420 HydrophobicContact CB-CB 3.82Å; R362-Y423 HydrophobicContact CB-CD2 4.16Å; R362-Y423 HydrophobicContact CG-CD2 4.14Å
363C98.8Very high97.8Very high0 Ų026.5 Ų26.50%013%0.125CC..Hα-helixtrans-63.1-42.5172.1-65.20000111.2L320 L359 L360 E361 E366 T367 F418 P420L320-C363 HydrophobicContact CD1-CB 3.77Å; L359-C363 PolarHBondContact O-N 3.21Å; L359-C363 PolarHBondContact O-SG 3.49Å; L360-C363 WeakPolarHBondContact O-CB 3.13Å; L360-C363 PolarHBondContact O-N 3.29Å; E361-C363 VanDerWaalsContact C-N 3.32Å; E361-C363 PolarHBondContact O-N 3.48Å; C363-E366 PolarHBondContact O-N 2.77Å; C363-T367 WeakPolarHBondContact O-CB 3.18Å; C363-T367 PolarHBondContact O-N 2.85Å; C363-T367 PolarHBondContact O-OG1 3.33Å; C363-F418 HydrophobicContact CB-CZ 4.22Å; C363-F418 WeakPolarHBondContact O-CZ 3.33Å; C363-P420 HydrophobicContact CB-CG 4.39Å; C363-P420 VanDerWaalsContact SG-CG 3.58Å
364L98.7Very high97.7Very high2 Ų228 Ų281%0.0113%0.134CC..Hα-helixtrans-65.7-43.3174.5179.151.8000111.7T316 L360 E361 R362 E366 T367 L368 Y450 I453 K454T316-L364 HydrophobicContact CG2-CD1 3.5Å; L360-L364 PolarHBondContact O-N 2.87Å; E361-L364 WeakPolarHBondContact O-CB 3.21Å; E361-L364 PolarHBondContact O-N 3.36Å; R362-L364 VanDerWaalsContact C-N 3.35Å; L364-E366 VanDerWaalsContact C-N 3.34Å; L364-E366 PolarHBondContact O-N 2.96Å; L364-T367 WeakPolarHBondContact O-CB 3.31Å; L364-T367 PolarHBondContact O-N 2.92Å; L364-L368 HydrophobicContact CD1-CD1 4.25Å; L364-L368 HydrophobicContact CD1-CG 4.29Å; L364-L368 HydrophobicContact CG-CD1 4.34Å; L364-L368 WeakPolarHBondContact O-CG 3.28Å; L364-L368 PolarHBondContact O-N 3.25Å; L364-Y450 HydrophobicContact CB-CE1 4.4Å; L364-Y450 HydrophobicContact CD2-CD1 3.51Å; L364-Y450 HydrophobicContact CD2-CE1 3.75Å; L364-Y450 HydrophobicContact CD2-CG 4.1Å; L364-Y450 HydrophobicContact CG-CD1 4.25Å; L364-Y450 HydrophobicContact CG-CE1 3.95Å; L364-I453 HydrophobicContact CD1-CB 4.37Å; L364-I453 HydrophobicContact CD1-CD1 3.99Å; L364-I453 HydrophobicContact CD1-CG2 3.73Å; L364-I453 HydrophobicContact CD2-CB 3.92Å; L364-I453 HydrophobicContact CD2-CD1 4.43Å; L364-I453 HydrophobicContact CD2-CG2 3.9Å; L364-I453 HydrophobicContact CG-CG2 4.43Å; L364-K454 HydrophobicContact CD2-CG 4.17Å
365K98.4Very high97.7Very high43 Ų4328.9 Ų28.919%0.18714%0.138CC..Hα-helixtrans-58.4-45.4174.8-163.8-178.5175.2-177.70111.1E361 R362 T367 L368 R369 Y423 D426 Y433E361-K365 WeakPolarHBondContact O-CB 3.47Å; E361-K365 PolarHBondContact O-N 2.92Å; R362-K365 PolarHBondContact O-N 3.29Å; K365-T367 PolarHBondContact O-N 2.88Å; K365-L368 PolarHBondContact O-N 3.37Å; K365-R369 PolarHBondContact O-N 3.5Å; K365-Y423 HydrophobicContact CB-CD2 4.33Å; K365-Y423 HydrophobicContact CB-CE2 3.82Å; K365-Y423 HydrophobicContact CD-CD1 3.76Å; K365-Y423 HydrophobicContact CD-CD2 3.91Å; K365-Y423 HydrophobicContact CD-CE1 3.73Å; K365-Y423 HydrophobicContact CD-CE2 3.88Å; K365-Y423 HydrophobicContact CD-CG 3.83Å; K365-Y423 VanDerWaalsContact CE-CE1 3.5Å; K365-Y423 HydrophobicContact CG-CD2 4.34Å; K365-Y423 HydrophobicContact CG-CE1 4.05Å; K365-Y423 HydrophobicContact CG-CE2 3.83Å; K365-Y423 PolarHBondContact O-OH 3.18Å; K365-D426 IonicContact NZ-OD2 3.29Å; K365-D426 PolarHBondContact NZ-OD2 3.39Å; K365-Y433 WeakPolarHBondContact CA-OH 3.26Å; K365-Y433 HydrophobicContact CD-CE1 4.43Å; K365-Y433 HydrophobicContact CG-CE1 3.81Å; K365-Y433 HydrophobicContact CG-CE2 4.26Å; K365-Y433 VanDerWaalsContact CG-CZ 3.49Å; K365-Y433 WeakPolarHBondContact CG-OH 3.41Å; K365-Y433 PolarHBondContact O-OH 2.93Å
366E98.4Very high97.7Very high0 Ų025 Ų250%012%0.123CC..Hα-helixtrans-68.6-34.5178.1-170.166.9170.100112.4R362 C363 L364 R369 L370 F418 R419 R422 Y423R362-E366 WeakPolarHBondContact O-CB 3.39Å; R362-E366 PolarHBondContact O-N 2.94Å; C363-E366 PolarHBondContact O-N 2.77Å; L364-E366 VanDerWaalsContact C-N 3.34Å; L364-E366 PolarHBondContact O-N 2.96Å; E366-R369 VanDerWaalsContact CD-NE 3.29Å; E366-R369 WeakPolarHBondContact O-CB 3.26Å; E366-R369 PolarHBondContact O-N 2.63Å; E366-R369 IonicContact OE1-CZ 3.14Å; E366-R369 IonicContact OE1-NE 3.64Å; E366-R369 PolarHBondContact OE1-NE 3.43Å; E366-R369 IonicContact OE1-NH2 2.87Å; E366-R369 PolarHBondContact OE1-NH2 2.9Å; E366-R369 WeakPolarHBondContact OE2-CD 3.43Å; E366-R369 IonicContact OE2-CZ 3.8Å; E366-R369 IonicContact OE2-NE 3.98Å; E366-R369 PolarHBondContact OE2-NE 2.84Å; E366-R369 IonicContact OE2-NH2 2.83Å; E366-L370 HydrophobicContact CG-CD1 4.46Å; E366-L370 PolarHBondContact O-N 3.05Å; E366-F418 HydrophobicContact CB-CD2 4.14Å; E366-F418 HydrophobicContact CB-CE2 3.79Å; E366-F418 HydrophobicContact CB-CZ 4.13Å; E366-F418 HydrophobicContact CG-CD1 4.48Å; E366-F418 HydrophobicContact CG-CD2 3.54Å; E366-F418 HydrophobicContact CG-CE2 3.74Å; E366-F418 HydrophobicContact CG-CG 3.94Å; E366-F418 HydrophobicContact CG-CZ 4.3Å; E366-R419 PolarHBondContact OE1-N 3.35Å; E366-R422 IonicContact OE1-CZ 3.08Å; E366-R422 IonicContact OE1-NE 2.79Å; E366-R422 PolarHBondContact OE1-NE 3.1Å; E366-R422 IonicContact OE1-NH2 3.47Å; E366-R422 PolarHBondContact OE1-NH2 3.45Å; E366-R422 WeakPolarHBondContact OE2-CD 3.42Å; E366-R422 IonicContact OE2-NE 3.34Å; E366-R422 PolarHBondContact OE2-NE 3.24Å; E366-Y423 HydrophobicContact CB-CE2 3.97Å; E366-Y423 PolarHBondContact OE2-OH 2.57Å
367T98.9Very high97.7Very high0 Ų021.6 Ų21.60%010%0.104CC..Hα-helixtrans-62.5-48.2173.2-58.10000110.4T316 W319 L320 F323 C363 L364 K365 R369 L370 R371 F418T316-T367 HydrophobicContact CG2-CG2 4.01Å; T316-T367 WeakPolarHBondContact O-CG2 3.1Å; W319-T367 HydrophobicContact CB-CG2 3.77Å; L320-T367 HydrophobicContact CB-CG2 4.08Å; F323-T367 HydrophobicContact CD2-CG2 4.26Å; F323-T367 HydrophobicContact CE2-CG2 4.3Å; C363-T367 WeakPolarHBondContact O-CB 3.18Å; C363-T367 PolarHBondContact O-N 2.85Å; C363-T367 PolarHBondContact O-OG1 3.33Å; L364-T367 WeakPolarHBondContact O-CB 3.31Å; L364-T367 PolarHBondContact O-N 2.92Å; K365-T367 PolarHBondContact O-N 2.88Å; T367-R369 PolarHBondContact O-N 3.48Å; T367-L370 PolarHBondContact O-N 2.94Å; T367-R371 CarbonylContact O-C 3.6Å; T367-R371 WeakPolarHBondContact O-CA 3.31Å; T367-R371 PolarHBondContact O-N 3Å; T367-F418 WeakPolarHBondContact OG1-CE2 3.27Å
368L98.6Very high97.6Very high6 Ų623.4 Ų23.43%0.03111%0.113CC..Hα-helixtrans-66.2-25177.1-74.5170.6000113T316 L364 K365 P372 H406 P435 F436T316-L368 HydrophobicContact CG2-CD2 3.65Å; T316-L368 HydrophobicContact CG2-CG 3.9Å; L364-L368 HydrophobicContact CD1-CD1 4.25Å; L364-L368 HydrophobicContact CD1-CG 4.29Å; L364-L368 HydrophobicContact CG-CD1 4.34Å; L364-L368 WeakPolarHBondContact O-CG 3.28Å; L364-L368 PolarHBondContact O-N 3.25Å; K365-L368 PolarHBondContact O-N 3.37Å; L368-P372 WeakPolarHBondContact O-CA 3.43Å; L368-P372 VanDerWaalsContact O-CB 3.31Å; L368-P372 WeakPolarHBondContact O-CB 3.3Å; L368-P372 WeakPolarHBondContact O-CD 3.34Å; L368-H406 PolarHBondContact O-ND1 2.96Å; L368-P435 HydrophobicContact CB-CB 3.92Å; L368-P435 HydrophobicContact CB-CG 4.25Å; L368-P435 HydrophobicContact CD2-CB 4.39Å; L368-F436 HydrophobicContact CD1-CE2 3.63Å; L368-F436 HydrophobicContact CD1-CZ 3.76Å
369R98.1Very high97.6Very high0 Ų020 Ų200%09%0.094CC..Hα-helixtrans-68.3-50.1171.8-168.3-17266.578.3-3.1111.5K365 E366 T367 H406 W412 R415 E417 Y433K365-R369 PolarHBondContact O-N 3.5Å; E366-R369 VanDerWaalsContact CD-NE 3.29Å; E366-R369 WeakPolarHBondContact O-CB 3.26Å; E366-R369 PolarHBondContact O-N 2.63Å; E366-R369 IonicContact OE1-CZ 3.14Å; E366-R369 IonicContact OE1-NE 3.64Å; E366-R369 PolarHBondContact OE1-NE 3.43Å; E366-R369 IonicContact OE1-NH2 2.87Å; E366-R369 PolarHBondContact OE1-NH2 2.9Å; E366-R369 WeakPolarHBondContact OE2-CD 3.43Å; E366-R369 IonicContact OE2-CZ 3.8Å; E366-R369 IonicContact OE2-NE 3.98Å; E366-R369 PolarHBondContact OE2-NE 2.84Å; E366-R369 IonicContact OE2-NH2 2.83Å; T367-R369 PolarHBondContact O-N 3.48Å; R369-H406 WeakPolarHBondContact CD-O 3.32Å; R369-H406 HydrophobicContact CG-CB 3.7Å; R369-H406 VanDerWaalsContact CG-O 3.23Å; R369-H406 WeakPolarHBondContact CG-O 3.3Å; R369-H406 PolarHBondContact NH1-O 2.97Å; R369-H406 WeakPolarHBondContact O-CB 3.27Å; R369-H406 PolarHBondContact O-ND1 2.73Å; R369-W412 VanDerWaalsContact CD-CE3 3.49Å; R369-W412 HydrophobicContact CG-CH2 4.24Å; R369-W412 HydrophobicContact CG-CZ2 4.37Å; R369-W412 HydrophobicContact CG-CZ3 4.39Å; R369-R415 PolarHBondContact NH1-O 3.46Å; R369-R415 PolarHBondContact NH2-O 2.82Å; R369-E417 PolarHBondContact NH2-O 3.3Å; R369-Y433 HydrophobicContact CB-CD2 4.23Å; R369-Y433 HydrophobicContact CB-CE2 3.79Å; R369-Y433 HydrophobicContact CG-CD2 4.21Å; R369-Y433 HydrophobicContact CG-CE2 4.29Å
370L98.2Very high97.6Very high1 Ų120.9 Ų20.91%0.00510%0.098CC..Hα-helixtrans-83.8-29.4-173.9-77.2171000113.3F323 E366 T367 P372 F418F323-L370 HydrophobicContact CE1-CD1 4.17Å; F323-L370 HydrophobicContact CE2-CB 4.46Å; F323-L370 HydrophobicContact CZ-CB 4.02Å; F323-L370 HydrophobicContact CZ-CD1 3.96Å; E366-L370 HydrophobicContact CG-CD1 4.46Å; E366-L370 PolarHBondContact O-N 3.05Å; T367-L370 PolarHBondContact O-N 2.94Å; L370-P372 VanDerWaalsContact C-CD 3.49Å; L370-F418 HydrophobicContact CD1-CB 3.95Å; L370-F418 HydrophobicContact CD1-CD2 3.94Å; L370-F418 HydrophobicContact CD1-CG 4.44Å
371R98.2Very high97.6Very high39 Ų3920.9 Ų20.915%0.14710%0.099CC..SBendtrans-136.454.9-174.7-58.7-66.5-178.5-83.3-5111.4W319 F323 T367W319-R371 HydrophobicContact CB-CB 4.08Å; W319-R371 HydrophobicContact CB-CG 4.09Å; W319-R371 HydrophobicContact CD2-CB 4.2Å; W319-R371 HydrophobicContact CD2-CG 3.66Å; W319-R371 HydrophobicContact CE3-CG 4.14Å; W319-R371 HydrophobicContact CG-CB 3.68Å; W319-R371 HydrophobicContact CG-CG 3.62Å; F323-R371 HydrophobicContact CE2-CG 3.94Å; F323-R371 HydrophobicContact CZ-CG 4.07Å; T367-R371 CarbonylContact O-C 3.6Å; T367-R371 WeakPolarHBondContact O-CA 3.31Å; T367-R371 PolarHBondContact O-N 3Å
372P97.8Very high97.6Very high4 Ų423 Ų233%0.02610%0.103CC..  trans-61130.9171.926-32.8000109.5L368 L370 I374 P402 T403L368-P372 WeakPolarHBondContact O-CA 3.43Å; L368-P372 VanDerWaalsContact O-CB 3.31Å; L368-P372 WeakPolarHBondContact O-CB 3.3Å; L368-P372 WeakPolarHBondContact O-CD 3.34Å; L370-P372 VanDerWaalsContact C-CD 3.49Å; P372-I374 VanDerWaalsContact C-N 3.28Å; P372-I374 PolarHBondContact O-N 2.8Å; P372-P402 HydrophobicContact CB-CB 4.29Å; P372-P402 HydrophobicContact CG-CB 4.19Å; P372-T403 HydrophobicContact CG-CG2 3.89Å
373P96.4Very high97.6Very high9 Ų923 Ų236%0.05811%0.109CC..SBendtrans-65.2-32.5-17722.8-32.7000112.6T312 I482T312-P373 HydrophobicContact CG2-CB 4.23Å; T312-P373 HydrophobicContact CG2-CG 4.01Å; P373-I482 HydrophobicContact CB-CG2 3.92Å
374I95Very high97.5Very high69 Ų6927.2 Ų27.235%0.35414%0.136SC..  trans-96.6100.4174.9-56.2-58.2000109.2P372 M377P372-I374 VanDerWaalsContact C-N 3.28Å; P372-I374 PolarHBondContact O-N 2.8Å; I374-M377 HydrophobicContact CG2-CG 4.23Å
375M94.5Very high97.4Very high26 Ų2628.1 Ų28.113%0.12814%0.14CC..  trans-78.4-24.7-173.877.9109.5138.600114.3F74 P78 S401 P402 T403 H483F74-M375 HydrophobicContact CE1-CE 4.33Å; F74-M375 HydrophobicContact CZ-CE 4.4Å; P78-M375 HydrophobicContact CB-CE 3.52Å; P78-M375 HydrophobicContact CB-SD 4.19Å; P78-M375 HydrophobicContact CG-CE 3.44Å; P78-M375 VanDerWaalsContact CG-CE 3.44Å; P78-M375 HydrophobicContact CG-SD 4.35Å; M375-S401 VanDerWaalsContact O-CA 3.28Å; M375-S401 WeakPolarHBondContact O-CA 3.06Å; M375-S401 WeakPolarHBondContact O-CB 3.32Å; M375-S401 PolarHBondContact O-OG 3.33Å; M375-P402 WeakPolarHBondContact O-CD 3.29Å; M375-T403 VanDerWaalsContact CA-OG1 3.23Å; M375-T403 WeakPolarHBondContact CA-OG1 3.26Å; M375-T403 WeakPolarHBondContact CB-OG1 3.49Å; M375-T403 PolarHBondContact O-OG1 3.42Å; M375-H483 VanDerWaalsContact CB-CE1 3.4Å; M375-H483 WeakPolarHBondContact CB-CE1 3.05Å; M375-H483 VanDerWaalsContact CE-CE1 3.43Å; M375-H483 WeakPolarHBondContact CE-CE1 3.49Å; M375-H483 WeakPolarHBondContact CE-NE2 3.45Å; M375-H483 WeakPolarHBondContact CG-CE1 3.45Å
376T94.8Very high97.3Very high19 Ų1930.6 Ų30.612%0.11716%0.159CC..  trans-144.8136.2-178.3-71.30000110.4Y104 M378 C399 V400Y104-T376 HydrophobicContact CE1-CG2 4.18Å; Y104-T376 WeakPolarHBondContact OH-CG2 3.5Å; Y104-T376 PolarHBondContact OH-OG1 3.42Å; T376-M378 HydrophobicContact CG2-CG 3.76Å; T376-M378 HydrophobicContact CG2-SD 4.48Å; T376-C399 HydrophobicContact CG2-CB 4.11Å; T376-V400 CarbonylContact C-O 3.4Å; T376-V400 WeakPolarHBondContact CA-O 3.44Å
377M96.8Very high97.2Very high23 Ų2331 Ų3111%0.11316%0.162CC..EExtended strand (participates in β ladder)trans-110.3136.7167.5-71.7171.4-80.700109.5M114 F115 I374 C399 V400 P402 I434M114-M377 HydrophobicContact SD-CB 4.15Å; F115-M377 HydrophobicContact CE1-CE 3.81Å; F115-M377 HydrophobicContact CE1-SD 3.94Å; F115-M377 HydrophobicContact CZ-CE 3.59Å; F115-M377 HydrophobicContact CZ-SD 4.33Å; I374-M377 HydrophobicContact CG2-CG 4.23Å; M377-C399 CarbonylContact O-C 3.57Å; M377-C399 VanDerWaalsContact O-CA 3.26Å; M377-C399 WeakPolarHBondContact O-CA 3.41Å; M377-V400 HydrophobicContact CE-CG1 4.43Å; M377-V400 PolarHBondContact N-O 3.03Å; M377-V400 PolarHBondContact O-N 3.41Å; M377-P402 HydrophobicContact CE-CG 3.33Å; M377-I434 HydrophobicContact CE-CD1 4.35Å
378M97.2Very high96.9Very high37 Ų3734 Ų3418%0.18219%0.186CC..EExtended strand (participates in β ladder)trans-124.9147.5-173.8-59.1177.8-83.700112.1F102 V127 Y128 T376 V398F102-M378 HydrophobicContact CE1-SD 4.26Å; V127-M378 HydrophobicContact CG1-CB 3.9Å; V127-M378 HydrophobicContact CG1-CE 4.3Å; V127-M378 HydrophobicContact CG1-SD 4.32Å; Y128-M378 HydrophobicContact CE1-CE 3.91Å; Y128-M378 PolarHBondContact OH-N 3.45Å; Y128-M378 PolarHBondContact OH-O 3.16Å; T376-M378 HydrophobicContact CG2-CG 3.76Å; T376-M378 HydrophobicContact CG2-SD 4.48Å; M378-V398 CarbonylContact C-O 3.5Å; M378-V398 WeakPolarHBondContact CA-O 3.32Å
379R98.1Very high96.7Very high13 Ų1336.3 Ų36.35%0.04921%0.212CC..EExtended strand (participates in β ladder)trans-139.4148.9170.6-63.1-63.9-178-84-6.4110.2M114 L122 N123 Q397 V398 H441M114-R379 HydrophobicContact CE-CB 4.48Å; M114-R379 HydrophobicContact CE-CG 4.18Å; M114-R379 HydrophobicContact CG-CG 4.17Å; M114-R379 HydrophobicContact SD-CG 4.35Å; L122-R379 HydrophobicContact CB-CB 3.74Å; L122-R379 HydrophobicContact CB-CG 4.03Å; L122-R379 WeakPolarHBondContact O-CD 3.27Å; N123-R379 CarbonylContact O-C 3.48Å; N123-R379 VanDerWaalsContact O-CA 3.31Å; N123-R379 WeakPolarHBondContact O-CA 3.13Å; R379-Q397 CarbonylContact O-C 3.51Å; R379-Q397 WeakPolarHBondContact O-CA 3.37Å; R379-V398 PolarHBondContact N-O 3.38Å; R379-V398 PolarHBondContact O-N 2.84Å; R379-H441 PolarHBondContact NH2-CD2 2.86Å; R379-H441 VanDerWaalsContact NH2-CG 3.31Å
380M98.3Very high96.7Very high27 Ų2738.5 Ų38.513%0.13322%0.221CC..EExtended strand (participates in β ladder)trans-86.8127.5169-175.659.867.400109.7L122 N123 D126 V127 R382 G395 Q397L122-M380 CarbonylContact C-O 3.47Å; L122-M380 WeakPolarHBondContact CA-O 3.42Å; N123-M380 PolarHBondContact N-O 2.91Å; N123-M380 PolarHBondContact O-N 2.84Å; D126-M380 HydrophobicContact CB-CB 3.56Å; D126-M380 HydrophobicContact CB-CG 4.05Å; V127-M380 HydrophobicContact CG2-CB 4.12Å; M380-R382 PolarHBondContact O-N 3.33Å; M380-G395 VanDerWaalsContact SD-C 3.6Å; M380-Q397 HydrophobicContact CE-CG 3.76Å; M380-Q397 HydrophobicContact SD-CG 4.45Å
381A98.5Very high96.7Very high1 Ų140.3 Ų40.31%0.00823%0.232CC..EExtended strand (participates in β ladder)trans-74.2113.5170.800000110.1L122 V394 G395 H396 V398L122-A381 HydrophobicContact CD2-CB 3.93Å; A381-V394 WeakPolarHBondContact O-CA 3.49Å; A381-V394 WeakPolarHBondContact O-CG1 3.34Å; A381-G395 PolarHBondContact O-N 2.84Å; A381-H396 PolarHBondContact N-O 2.62Å; A381-V398 HydrophobicContact CB-CG2 4.14Å
382R98Very high96.7Very high118 Ų11838.5 Ų38.545%0.44523%0.225SC..SBendtrans-94.7-22.7174.8-73.1-172.3173.4-172.5-0.3112.7E120 D121 N123 D126 M380 V394E120-R382 VanDerWaalsContact O-CB 3.31Å; E120-R382 WeakPolarHBondContact O-CB 3.4Å; D121-R382 PolarHBondContact O-N 3.49Å; N123-R382 HydrophobicContact CB-CG 4.06Å; N123-R382 VanDerWaalsContact CG-CZ 3.48Å; D126-R382 IonicContact OD1-CZ 2.71Å; D126-R382 IonicContact OD1-NE 3.8Å; D126-R382 IonicContact OD1-NH2 3.83Å; D126-R382 PolarHBondContact OD1-NH2 3.08Å; D126-R382 IonicContact OD2-CZ 2.71Å; D126-R382 IonicContact OD2-NE 3.68Å; D126-R382 PolarHBondContact OD2-NE 3.05Å; D126-R382 IonicContact OD2-NH2 2.67Å; D126-R382 PolarHBondContact OD2-NH2 2.79Å; D126-R382 VanDerWaalsContact OD2-NH2 3.17Å; M380-R382 PolarHBondContact O-N 3.33Å; R382-V394 WeakPolarHBondContact O-CG2 3.3Å
383T97.4Very high96.6Very high47 Ų4739.9 Ų39.929%0.28823%0.234SC..SBendtrans-128.2153.6174.258.10000109.2D121 Q385D121-T383 WeakPolarHBondContact CA-OG1 3.39Å; D121-T383 WeakPolarHBondContact CB-OG1 3.18Å; D121-T383 PolarHBondContact OD1-OG1 3.07Å; T383-Q385 PolarHBondContact O-N 3.39Å; T383-Q385 PolarHBondContact O-NE2 3.19Å; T383-Q385 PolarHBondContact OG1-NE2 2.8Å
384P96.9Very high96.6Very high87 Ų8743.4 Ų43.457%0.56526%0.255SS*.  trans-57.4131.7173.3-2333.7000110.9T391 I392 V394P384-T391 HydrophobicContact CB-CG2 4.35Å; P384-I392 WeakPolarHBondContact CA-O 3.27Å; P384-V394 HydrophobicContact CG-CG2 4.21Å
385Q97.6Very high96.7Very high22 Ų2242 Ų4210%0.10326%0.258CS..EExtended strand (participates in β ladder)trans-116.3157.1-179.6-61.9-60.6-68.800111L113 L122 T383 T391 I392L113-Q385 HydrophobicContact CD1-CB 4.31Å; L113-Q385 HydrophobicContact CD2-CB 3.89Å; L122-Q385 HydrophobicContact CD2-CG 3.78Å; L122-Q385 HydrophobicContact CG-CG 4.1Å; T383-Q385 PolarHBondContact O-N 3.39Å; T383-Q385 PolarHBondContact O-NE2 3.19Å; T383-Q385 PolarHBondContact OG1-NE2 2.8Å; Q385-T391 CarbonylContact O-C 3.51Å; Q385-T391 WeakPolarHBondContact O-CA 3.29Å; Q385-I392 HydrophobicContact CB-CB 4.28Å; Q385-I392 PolarHBondContact N-O 2.8Å; Q385-I392 PolarHBondContact O-N 2.95Å
386T96.6Very high96.8Very high95 Ų9542.2 Ų42.258%0.58326%0.258SS*.EExtended strand (participates in β ladder)trans-121.3129.1176.7-56.20000111.1Y390T386-Y390 CarbonylContact C-O 3.57Å; T386-Y390 VanDerWaalsContact CA-O 3.25Å; T386-Y390 WeakPolarHBondContact CA-O 3.38Å
387A95.1Very high97Very high9 Ų941.9 Ų41.97%0.07426%0.255CS..EExtended strand (participates in β ladder)trans-145.3135.217300000110.9V92 L105 L113 G389 Y390 I392V92-A387 HydrophobicContact CG2-CB 4.23Å; L105-A387 HydrophobicContact CD2-CB 3.98Å; L113-A387 HydrophobicContact CB-CB 4.37Å; L113-A387 HydrophobicContact CD2-CB 3.69Å; A387-G389 PolarHBondContact O-N 2.92Å; A387-G389 VanDerWaalsContact O-N 3.13Å; A387-Y390 PolarHBondContact N-O 2.79Å; A387-Y390 WeakPolarHBondContact O-CB 3.45Å; A387-Y390 PolarHBondContact O-N 3.49Å; A387-I392 HydrophobicContact CB-CD1 4.42Å
388A93.9Very high97.1Very high61 Ų6140.8 Ų40.850%0.50425%0.25SC..THydrogen-bonded Turntrans50.136.217900000114.2V92 Y390V92-A388 HydrophobicContact CB-CB 4.49Å; V92-A388 HydrophobicContact CG2-CB 3.69Å; A388-Y390 VanDerWaalsContact C-N 3.29Å; A388-Y390 HydrophobicContact CB-CD2 4.3Å; A388-Y390 WeakPolarHBondContact O-CD2 3.35Å; A388-Y390 PolarHBondContact O-N 2.94Å
389G93.8Very high97.1Very high55 Ų5539 Ų3957%0.56724%0.241SC*.THydrogen-bonded Turntrans76.210.7-177.900000115.1A387A387-G389 PolarHBondContact O-N 2.92Å; A387-G389 VanDerWaalsContact O-N 3.13Å
390Y97.3Very high97.2Very high47 Ų4738.4 Ų38.418%0.18424%0.239CC..EExtended strand (participates in β ladder)trans-108.9145.9175-60.7-73.4000112.3K56 Y57 P58 V92 T386 A387 A388K56-Y390 HydrophobicContact CD-CD1 4.13Å; K56-Y390 HydrophobicContact CD-CE1 4.01Å; K56-Y390 HydrophobicContact CG-CD1 3.83Å; K56-Y390 HydrophobicContact CG-CE1 3.96Å; K56-Y390 CarbonylContact O-C 3.58Å; K56-Y390 WeakPolarHBondContact O-CA 3.31Å; Y57-Y390 VanDerWaalsContact C-CD1 3.47Å; Y57-Y390 WeakPolarHBondContact O-CD1 3.29Å; Y57-Y390 WeakPolarHBondContact O-CE1 3.48Å; P58-Y390 HydrophobicContact CG-CG 4.41Å; V92-Y390 HydrophobicContact CB-CD2 3.99Å; V92-Y390 HydrophobicContact CB-CE2 4.41Å; V92-Y390 HydrophobicContact CG1-CD2 4.17Å; T386-Y390 CarbonylContact C-O 3.57Å; T386-Y390 VanDerWaalsContact CA-O 3.25Å; T386-Y390 WeakPolarHBondContact CA-O 3.38Å; A387-Y390 PolarHBondContact N-O 2.79Å; A387-Y390 WeakPolarHBondContact O-CB 3.45Å; A387-Y390 PolarHBondContact O-N 3.49Å; A388-Y390 VanDerWaalsContact C-N 3.29Å; A388-Y390 HydrophobicContact CB-CD2 4.3Å; A388-Y390 WeakPolarHBondContact O-CD2 3.35Å; A388-Y390 PolarHBondContact O-N 2.94Å
391T97.8Very high97.1Very high39 Ų3937.1 Ų37.124%0.23923%0.232CC..EExtended strand (participates in β ladder)trans-95.7118.4171.7-54.70000110.2K56 Y57 P58 P384 Q385K56-T391 PolarHBondContact O-N 2.84Å; Y57-T391 WeakPolarHBondContact CD1-O 3.38Å; P58-T391 WeakPolarHBondContact CD-O 3.34Å; P384-T391 HydrophobicContact CB-CG2 4.35Å; Q385-T391 CarbonylContact O-C 3.51Å; Q385-T391 WeakPolarHBondContact O-CA 3.29Å
392I98Very high97.1Very high0 Ų037.1 Ų37.10%023%0.232CC..EExtended strand (participates in β ladder)trans-91.7117.8174.9-53.8175.5000108P58 T103 L105 L113 P384 Q385 A387 H396 V398P58-I392 HydrophobicContact CG-CG1 4.2Å; T103-I392 HydrophobicContact CG2-CD1 3.92Å; T103-I392 HydrophobicContact CG2-CG1 4.12Å; T103-I392 HydrophobicContact CG2-CG2 4.39Å; L105-I392 HydrophobicContact CD2-CD1 4.02Å; L113-I392 HydrophobicContact CD2-CD1 3.91Å; P384-I392 WeakPolarHBondContact CA-O 3.27Å; Q385-I392 HydrophobicContact CB-CB 4.28Å; Q385-I392 PolarHBondContact N-O 2.8Å; Q385-I392 PolarHBondContact O-N 2.95Å; A387-I392 HydrophobicContact CB-CD1 4.42Å; I392-H396 HydrophobicContact CG2-CB 3.84Å; I392-V398 HydrophobicContact CD1-CG1 4.48Å; I392-V398 HydrophobicContact CD1-CG2 4.46Å; I392-V398 HydrophobicContact CG2-CG2 3.88Å
393P96.3Very high97Very high34 Ų3431.7 Ų31.722%0.22121%0.212CC..PPolyproline II helixtrans-77.2163.3-177.131.9-35.3000112.5Y57 H396Y57-P393 HydrophobicContact CD1-CG 4.43Å; Y57-P393 HydrophobicContact CE1-CB 4.36Å; Y57-P393 HydrophobicContact CE1-CG 4.36Å; P393-H396 WeakPolarHBondContact CG-NE2 3.13Å; P393-H396 PolarHBondContact O-N 3.09Å
394V97.2Very high97Very high83 Ų8329.4 Ų29.450%0.50320%0.199SC..THydrogen-bonded Turntrans-58143.1173.6178.80000110.5A381 R382 P384 H396A381-V394 WeakPolarHBondContact O-CA 3.49Å; A381-V394 WeakPolarHBondContact O-CG1 3.34Å; R382-V394 WeakPolarHBondContact O-CG2 3.3Å; P384-V394 HydrophobicContact CG-CG2 4.21Å; V394-H396 VanDerWaalsContact C-N 3.33Å; V394-H396 PolarHBondContact O-N 2.81Å
395G96.2Very high97Very high39 Ų3925.3 Ų25.340%0.40217%0.172SC..THydrogen-bonded Turntrans86.8-6.2178.700000115M380 A381M380-G395 VanDerWaalsContact SD-C 3.6Å; A381-G395 PolarHBondContact O-N 2.84Å
396H98.1Very high97Very high31 Ų3124.3 Ų24.314%0.14417%0.167CC..  trans-70.5138.6168.1-81-150000110.8T101 T103 A381 I392 P393 V394 V398T101-H396 VanDerWaalsContact CG2-CE1 3.4Å; T101-H396 WeakPolarHBondContact CG2-CE1 3.44Å; T101-H396 WeakPolarHBondContact CG2-NE2 3.49Å; T103-H396 PolarHBondContact OG1-ND1 3.08Å; A381-H396 PolarHBondContact N-O 2.62Å; I392-H396 HydrophobicContact CG2-CB 3.84Å; P393-H396 WeakPolarHBondContact CG-NE2 3.13Å; P393-H396 PolarHBondContact O-N 3.09Å; V394-H396 VanDerWaalsContact C-N 3.33Å; V394-H396 PolarHBondContact O-N 2.81Å; H396-V398 PolarHBondContact O-N 2.92Å
397Q98Very high96.9Very high11 Ų1120.3 Ų20.35%0.05114%0.142CC..EExtended strand (participates in β ladder)trans-84.3105164.8-67.2-168.512.100108.6T101 F102 T103 R379 M380 C399T101-Q397 PolarHBondContact O-N 3.23Å; F102-Q397 CarbonylContact C-O 3.46Å; F102-Q397 VanDerWaalsContact CA-O 3.27Å; F102-Q397 WeakPolarHBondContact CA-O 3.45Å; F102-Q397 HydrophobicContact CD1-CB 3.89Å; F102-Q397 HydrophobicContact CE1-CB 3.99Å; T103-Q397 PolarHBondContact N-O 3.01Å; R379-Q397 CarbonylContact O-C 3.51Å; R379-Q397 WeakPolarHBondContact O-CA 3.37Å; M380-Q397 HydrophobicContact CE-CG 3.76Å; M380-Q397 HydrophobicContact SD-CG 4.45Å; Q397-C399 PolarHBondContact O-SG 3.01Å
398V98.6Very high96.9Very high0 Ų020.3 Ų20.30%014%0.14CC..EExtended strand (participates in β ladder)trans-82.2132.9179-173.80000108.8T103 L105 M114 L122 M378 R379 A381 I392 H396T103-V398 CarbonylContact O-C 3.56Å; T103-V398 WeakPolarHBondContact O-CA 3.47Å; L105-V398 HydrophobicContact CD1-CG1 3.46Å; L105-V398 VanDerWaalsContact CD1-CG1 3.46Å; L105-V398 HydrophobicContact CG-CG1 3.84Å; M114-V398 VanDerWaalsContact CE-C 3.44Å; M114-V398 HydrophobicContact CE-CB 4.34Å; M114-V398 HydrophobicContact CE-CG1 4.04Å; M114-V398 WeakPolarHBondContact CE-O 3.34Å; L122-V398 HydrophobicContact CD1-CG1 4.39Å; L122-V398 HydrophobicContact CD2-CB 4.17Å; L122-V398 HydrophobicContact CD2-CG2 3.77Å; M378-V398 CarbonylContact C-O 3.5Å; M378-V398 WeakPolarHBondContact CA-O 3.32Å; R379-V398 PolarHBondContact N-O 3.38Å; R379-V398 PolarHBondContact O-N 2.84Å; A381-V398 HydrophobicContact CB-CG2 4.14Å; I392-V398 HydrophobicContact CD1-CG1 4.48Å; I392-V398 HydrophobicContact CD1-CG2 4.46Å; I392-V398 HydrophobicContact CG2-CG2 3.88Å; H396-V398 PolarHBondContact O-N 2.92Å
399C98.5Very high96.7Very high0 Ų025 Ų250%015%0.145CC..EExtended strand (participates in β ladder)trans-129.4144-170.4-57.60000112.1T103 Y104 L105 T376 M377 Q397T103-C399 PolarHBondContact O-N 3.28Å; Y104-C399 CarbonylContact C-O 3.51Å; Y104-C399 WeakPolarHBondContact CA-O 3.26Å; Y104-C399 HydrophobicContact CD1-CB 3.72Å; Y104-C399 HydrophobicContact CD2-CB 3.7Å; Y104-C399 HydrophobicContact CE1-CB 3.61Å; Y104-C399 HydrophobicContact CE2-CB 3.61Å; Y104-C399 HydrophobicContact CG-CB 3.79Å; L105-C399 PolarHBondContact N-O 2.93Å; T376-C399 HydrophobicContact CG2-CB 4.11Å; M377-C399 CarbonylContact O-C 3.57Å; M377-C399 VanDerWaalsContact O-CA 3.26Å; M377-C399 WeakPolarHBondContact O-CA 3.41Å; Q397-C399 PolarHBondContact O-SG 3.01Å
400V98.3Very high96.4Very high0 Ų027.8 Ų27.80%015%0.147CC..EExtended strand (participates in β ladder)trans-124.9139.6164.8169.60000107.7L105 A111 M114 F115 T376 M377 I434L105-V400 HydrophobicContact CB-CG2 4.03Å; A111-V400 HydrophobicContact CB-CG1 3.99Å; A111-V400 HydrophobicContact CB-CG2 3.81Å; M114-V400 HydrophobicContact CB-CG2 3.85Å; M114-V400 HydrophobicContact CE-CB 4.33Å; M114-V400 HydrophobicContact CE-CG2 3.93Å; M114-V400 HydrophobicContact CG-CG2 4.29Å; M114-V400 HydrophobicContact SD-CB 3.85Å; M114-V400 HydrophobicContact SD-CG2 3.61Å; F115-V400 HydrophobicContact CE2-CG1 3.96Å; F115-V400 HydrophobicContact CE2-CG2 4.49Å; F115-V400 HydrophobicContact CZ-CB 4.35Å; F115-V400 HydrophobicContact CZ-CG1 3.84Å; T376-V400 CarbonylContact C-O 3.4Å; T376-V400 WeakPolarHBondContact CA-O 3.44Å; M377-V400 HydrophobicContact CE-CG1 4.43Å; M377-V400 PolarHBondContact N-O 3.03Å; M377-V400 PolarHBondContact O-N 3.41Å; V400-I434 HydrophobicContact CG1-CD1 3.73Å
401S97.9Very high96.1Very high0 Ų027.5 Ų27.50%015%0.154CC..  trans-110.8107.2173.6-177.20000111.2M375 T403 V404 N405M375-S401 VanDerWaalsContact O-CA 3.28Å; M375-S401 WeakPolarHBondContact O-CA 3.06Å; M375-S401 WeakPolarHBondContact O-CB 3.32Å; M375-S401 PolarHBondContact O-OG 3.33Å; S401-T403 VanDerWaalsContact C-N 3.26Å; S401-T403 PolarHBondContact O-N 3.09Å; S401-V404 PolarHBondContact O-N 2.73Å; S401-V404 PolarHBondContact OG-N 3.15Å; S401-N405 PolarHBondContact O-N 3.09Å; S401-N405 VanDerWaalsContact O-N 3.08Å
402P97.4Very high95.8Very high1 Ų126.5 Ų26.51%0.00615%0.146CC..Hα-helixtrans-49.1-50.8168.2-32.138.9000111.7P372 M375 M377 V404 N405 H406 I434P372-P402 HydrophobicContact CB-CB 4.29Å; P372-P402 HydrophobicContact CG-CB 4.19Å; M375-P402 WeakPolarHBondContact O-CD 3.29Å; M377-P402 HydrophobicContact CE-CG 3.33Å; P402-V404 PolarHBondContact O-N 3.12Å; P402-V404 VanDerWaalsContact O-N 3.11Å; P402-N405 PolarHBondContact O-N 3.37Å; P402-N405 VanDerWaalsContact O-N 3.13Å; P402-H406 VanDerWaalsContact O-CB 3.27Å; P402-H406 WeakPolarHBondContact O-CB 3.5Å; P402-H406 PolarHBondContact O-CD2 3.01Å; P402-H406 PolarHBondContact O-N 2.85Å; P402-H406 PolarHBondContact O-NE2 2.97Å; P402-I434 HydrophobicContact CB-CG1 4.19Å; P402-I434 HydrophobicContact CG-CD1 4.3Å; P402-I434 HydrophobicContact CG-CG1 4.33Å
403T96.7Very high95.5Very high4 Ų434 Ų343%0.02518%0.183CC..Hα-helixtrans-57.9-32.6-175.2-25.60000113.7I79 P372 M375 S401 R407I79-T403 HydrophobicContact CD1-CG2 3.88Å; I79-T403 HydrophobicContact CG1-CG2 4.48Å; P372-T403 HydrophobicContact CG-CG2 3.89Å; M375-T403 VanDerWaalsContact CA-OG1 3.23Å; M375-T403 WeakPolarHBondContact CA-OG1 3.26Å; M375-T403 WeakPolarHBondContact CB-OG1 3.49Å; M375-T403 PolarHBondContact O-OG1 3.42Å; S401-T403 VanDerWaalsContact C-N 3.26Å; S401-T403 PolarHBondContact O-N 3.09Å; T403-R407 VanDerWaalsContact O-CG 3.3Å; T403-R407 WeakPolarHBondContact O-CG 3.42Å; T403-R407 PolarHBondContact O-NE 3.02Å
404V97.4Very high95.4Very high0 Ų037.4 Ų37.40%020%0.196CC..Hα-helixtrans-79.1-51.5175.8177.50000109.8I79 L82 E83 L106 S401 P402 H406 R407 L408I79-V404 HydrophobicContact CD1-CG2 4.5Å; L82-V404 HydrophobicContact CB-CG2 3.82Å; L82-V404 HydrophobicContact CD1-CG2 3.93Å; E83-V404 HydrophobicContact CG-CG1 4.48Å; L106-V404 HydrophobicContact CD1-CG1 4.07Å; L106-V404 HydrophobicContact CD2-CB 4.14Å; L106-V404 HydrophobicContact CD2-CG1 4.11Å; S401-V404 PolarHBondContact O-N 2.73Å; S401-V404 PolarHBondContact OG-N 3.15Å; P402-V404 PolarHBondContact O-N 3.12Å; P402-V404 VanDerWaalsContact O-N 3.11Å; V404-H406 PolarHBondContact O-N 3.28Å; V404-H406 VanDerWaalsContact O-N 3.14Å; V404-R407 CarbonylContact O-C 3.54Å; V404-R407 PolarHBondContact O-N 3.11Å; V404-L408 HydrophobicContact CG1-CD2 4.09Å; V404-L408 HydrophobicContact CG1-CG 4.18Å; V404-L408 WeakPolarHBondContact O-CG 3.29Å; V404-L408 PolarHBondContact O-N 2.74Å
405N97.1Very high95.2Very high1 Ų135 Ų351%0.00518%0.178CC..Hα-helixtrans-54.2-37.6179.6-80.930.3000112.8G107 S401 P402 R407 W412 F431 A432 I434G107-N405 PolarHBondContact N-OD1 3.43Å; G107-N405 PolarHBondContact O-ND2 2.84Å; S401-N405 PolarHBondContact O-N 3.09Å; S401-N405 VanDerWaalsContact O-N 3.08Å; P402-N405 PolarHBondContact O-N 3.37Å; P402-N405 VanDerWaalsContact O-N 3.13Å; N405-R407 PolarHBondContact O-N 3.2Å; N405-W412 PolarHBondContact O-NE1 3.36Å; N405-F431 PolarHBondContact ND2-O 3.09Å; N405-A432 CarbonylContact C-O 3.51Å; N405-I434 HydrophobicContact CB-CD1 4.42Å
406H96.6Very high95.2Very high0 Ų037.4 Ų37.40%018%0.18CC..THydrogen-bonded Turntrans-72.4-8.2-178.2-67.5-174.4000114.2L368 R369 P402 V404 W412 A432 I434L368-H406 PolarHBondContact O-ND1 2.96Å; R369-H406 WeakPolarHBondContact CD-O 3.32Å; R369-H406 HydrophobicContact CG-CB 3.7Å; R369-H406 VanDerWaalsContact CG-O 3.23Å; R369-H406 WeakPolarHBondContact CG-O 3.3Å; R369-H406 PolarHBondContact NH1-O 2.97Å; R369-H406 WeakPolarHBondContact O-CB 3.27Å; R369-H406 PolarHBondContact O-ND1 2.73Å; P402-H406 VanDerWaalsContact O-CB 3.27Å; P402-H406 WeakPolarHBondContact O-CB 3.5Å; P402-H406 PolarHBondContact O-CD2 3.01Å; P402-H406 PolarHBondContact O-N 2.85Å; P402-H406 PolarHBondContact O-NE2 2.97Å; V404-H406 PolarHBondContact O-N 3.28Å; V404-H406 VanDerWaalsContact O-N 3.14Å; H406-W412 VanDerWaalsContact C-CD1 3.41Å; H406-W412 PolarHBondContact O-NE1 3.27Å; H406-A432 WeakPolarHBondContact CA-O 3.34Å; H406-A432 PolarHBondContact CD2-O 2.81Å; H406-A432 PolarHBondContact N-O 3.37Å; H406-I434 VanDerWaalsContact NE2-CG1 3.33Å; H406-I434 WeakPolarHBondContact NE2-CG1 3.24Å; H406-I434 PolarHBondContact NE2-N 3.48Å
407R95.1Very high95.2Very high12 Ų1241.5 Ų41.55%0.04520%0.199CC..THydrogen-bonded Turntrans-14119.6178.871.9177.6124.8174.7-2.7113.5E83 T403 V404 N405 R409 R415E83-R407 WeakPolarHBondContact OE1-CD 3.29Å; E83-R407 IonicContact OE1-NE 3.52Å; T403-R407 VanDerWaalsContact O-CG 3.3Å; T403-R407 WeakPolarHBondContact O-CG 3.42Å; T403-R407 PolarHBondContact O-NE 3.02Å; V404-R407 CarbonylContact O-C 3.54Å; V404-R407 PolarHBondContact O-N 3.11Å; N405-R407 PolarHBondContact O-N 3.2Å; R407-R409 PolarHBondContact O-N 3.3Å; R407-R415 HydrophobicContact CB-CB 4.23Å; R407-R415 HydrophobicContact CB-CG 4.46Å; R407-R415 WeakPolarHBondContact O-CB 3.22Å; R407-R415 WeakPolarHBondContact O-CD 3.28Å; R407-R415 PolarHBondContact O-NH1 2.89Å
408L94.1Very high95.2Very high9 Ų942.3 Ų42.35%0.04720%0.202CC..  trans-57.9138.1174.3-92173.1000109.9Y86 V404 D410 A411 W412Y86-L408 HydrophobicContact CD1-CD2 3.88Å; Y86-L408 HydrophobicContact CD2-CD2 4.24Å; Y86-L408 HydrophobicContact CE1-CD2 3.74Å; Y86-L408 HydrophobicContact CE2-CD2 4.08Å; Y86-L408 HydrophobicContact CG-CD2 4.13Å; V404-L408 HydrophobicContact CG1-CD2 4.09Å; V404-L408 HydrophobicContact CG1-CG 4.18Å; V404-L408 WeakPolarHBondContact O-CG 3.29Å; V404-L408 PolarHBondContact O-N 2.74Å; L408-D410 VanDerWaalsContact C-N 3.29Å; L408-D410 WeakPolarHBondContact CB-OD1 3.33Å; L408-D410 PolarHBondContact O-N 3.48Å; L408-A411 HydrophobicContact CB-CB 4.29Å; L408-A411 PolarHBondContact O-N 3.45Å; L408-W412 PolarHBondContact O-N 2.8Å
409R90.2Very high95.1Very high159 Ų15947.4 Ų47.460%0.622%0.222SC*.THydrogen-bonded Turntrans-65.1-32.8-171.8-68179.4-175.2-81.31.7112.9E87 R407E87-R409 IonicContact OE1-CZ 3.05Å; E87-R409 IonicContact OE1-NE 2.79Å; E87-R409 PolarHBondContact OE1-NE 2.8Å; E87-R409 IonicContact OE1-NH2 3.23Å; R407-R409 PolarHBondContact O-N 3.3Å
410D88.4Confident95Very high113 Ų11347.5 Ų47.560%0.60422%0.222SC*.THydrogen-bonded Turntrans-80.4-23-179.958.4-14.7000113.1Y86 L408Y86-D410 PolarHBondContact OH-OD2 2.81Å; Y86-D410 VanDerWaalsContact OH-OD2 3.05Å; L408-D410 VanDerWaalsContact C-N 3.29Å; L408-D410 WeakPolarHBondContact CB-OD1 3.33Å; L408-D410 PolarHBondContact O-N 3.48Å
411A89.4Confident94.8Very high42 Ų4249.6 Ų49.635%0.34723%0.232SC..THydrogen-bonded Turntrans-102.2-24.9-177.900000114.6L408 A432L408-A411 HydrophobicContact CB-CB 4.29Å; L408-A411 PolarHBondContact O-N 3.45Å; A411-A432 HydrophobicContact CB-CB 4.46Å
412W93Very high94.6Very high17 Ų1751.3 Ų51.36%0.06424%0.239CC..  trans-126.6112.4-173.2-6288.8000112.4R369 N405 H406 L408 R415 Y423 A428 A432 Y433R369-W412 VanDerWaalsContact CD-CE3 3.49Å; R369-W412 HydrophobicContact CG-CH2 4.24Å; R369-W412 HydrophobicContact CG-CZ2 4.37Å; R369-W412 HydrophobicContact CG-CZ3 4.39Å; N405-W412 PolarHBondContact O-NE1 3.36Å; H406-W412 VanDerWaalsContact C-CD1 3.41Å; H406-W412 PolarHBondContact O-NE1 3.27Å; L408-W412 PolarHBondContact O-N 2.8Å; W412-R415 HydrophobicContact CB-CB 3.96Å; W412-R415 WeakPolarHBondContact O-CB 3.31Å; W412-Y423 HydrophobicContact CH2-CE1 4.33Å; W412-Y423 HydrophobicContact CZ3-CE1 4.16Å; W412-A428 HydrophobicContact CH2-CB 4.14Å; W412-A428 HydrophobicContact CZ2-CB 4.41Å; W412-A432 HydrophobicContact CZ2-CB 4.3Å; W412-Y433 HydrophobicContact CH2-CD2 4.14Å; W412-Y433 HydrophobicContact CH2-CG 4.43Å; W412-Y433 HydrophobicContact CZ2-CD2 4.32Å
413M91.3Very high94.4Very high158 Ų15852.3 Ų52.378%0.77824%0.242SC*.THydrogen-bonded Turntrans-64.5141.9166.7-65.8-169.5-70.700110.6R415 R422M413-R415 PolarHBondContact O-N 3.29Å; M413-R422 PolarHBondContact O-NH1 2.87Å; M413-R422 PolarHBondContact O-NH2 3.09Å
414E93.6Very high94Very high106 Ų10657.4 Ų57.450%0.49527%0.269SS..THydrogen-bonded Turntrans48.647.7-178.6-61.2174.7134.600110.9M416 E417 R419 R422E414-M416 PolarHBondContact O-N 3.3Å; E414-E417 HydrophobicContact CB-CB 4.12Å; E414-E417 HydrophobicContact CB-CG 3.9Å; E414-E417 PolarHBondContact O-N 2.98Å; E414-R419 IonicContact OE2-CZ 3.88Å; E414-R419 IonicContact OE2-NH1 3.04Å; E414-R419 PolarHBondContact OE2-NH1 3.03Å; E414-R422 PolarHBondContact O-NH2 2.84Å
415R94.1Very high93.1Very high32 Ų3263.6 Ų63.612%0.12130%0.302CS..THydrogen-bonded Turntrans-55.3-24.8-164.178.1-160.7-168.181.7-4.4115.2E83 R369 R407 W412 M413E83-R415 IonicContact OE1-CZ 3.01Å; E83-R415 IonicContact OE1-NH1 3.73Å; E83-R415 PolarHBondContact OE1-NH1 2.8Å; E83-R415 IonicContact OE1-NH2 3Å; E83-R415 IonicContact OE2-CZ 2.73Å; E83-R415 IonicContact OE2-NH1 2.73Å; E83-R415 PolarHBondContact OE2-NH1 2.84Å; E83-R415 IonicContact OE2-NH2 3.6Å; E83-R415 PolarHBondContact OE2-NH2 2.85Å; R369-R415 PolarHBondContact NH1-O 3.46Å; R369-R415 PolarHBondContact NH2-O 2.82Å; R407-R415 HydrophobicContact CB-CB 4.23Å; R407-R415 HydrophobicContact CB-CG 4.46Å; R407-R415 WeakPolarHBondContact O-CB 3.22Å; R407-R415 WeakPolarHBondContact O-CD 3.28Å; R407-R415 PolarHBondContact O-NH1 2.89Å; W412-R415 HydrophobicContact CB-CB 3.96Å; W412-R415 WeakPolarHBondContact O-CB 3.31Å; M413-R415 PolarHBondContact O-N 3.29Å
416M96.1Very high91.6Very high90 Ų9068.2 Ų68.244%0.44333%0.327SS..THydrogen-bonded Turntrans-97.5-15.3-177.4-61.5-55.3-69.500113.2E414E414-M416 PolarHBondContact O-N 3.3Å
417E96.6Very high89.9Confident117 Ų11774.5 Ų74.555%0.54737%0.365SS..SBendtrans-77.1136.8-178.5-61-54.7141.400110.8R369 E414 R419 R422R369-E417 PolarHBondContact NH2-O 3.3Å; E414-E417 HydrophobicContact CB-CB 4.12Å; E414-E417 HydrophobicContact CB-CG 3.9Å; E414-E417 PolarHBondContact O-N 2.98Å; E417-R419 PolarHBondContact O-N 2.87Å; E417-R422 PolarHBondContact O-NH2 3.32Å
418F98.2Very high88.5Confident28 Ų2876 Ų7612%0.12338%0.38CS..  trans-80.996.7170.5-174.8-91.3000108.8L320 F323 L330 C363 E366 T367 L370 P420L320-F418 HydrophobicContact CD1-CZ 4.48Å; F323-F418 HydrophobicContact CB-CD1 3.94Å; F323-F418 HydrophobicContact CB-CD2 3.76Å; F323-F418 HydrophobicContact CB-CE1 3.82Å; F323-F418 HydrophobicContact CB-CE2 3.66Å; F323-F418 HydrophobicContact CB-CG 3.91Å; F323-F418 HydrophobicContact CB-CZ 3.7Å; F323-F418 HydrophobicContact CD1-CB 3.69Å; F323-F418 HydrophobicContact CD1-CD1 4.38Å; F323-F418 AromaticContact CD1-CD2 3.43Å; F323-F418 HydrophobicContact CD1-CD2 3.43Å; F323-F418 VanDerWaalsContact CD1-CD2 3.43Å; F323-F418 HydrophobicContact CD1-CE2 4.15Å; F323-F418 AromaticContact CD1-CG 3.58Å; F323-F418 HydrophobicContact CD1-CG 3.58Å; F323-F418 AromaticContact CD2-CD2 3.45Å; F323-F418 HydrophobicContact CD2-CD2 3.45Å; F323-F418 VanDerWaalsContact CD2-CD2 3.45Å; F323-F418 AromaticContact CD2-CE2 3.39Å; F323-F418 HydrophobicContact CD2-CE2 3.39Å; F323-F418 HydrophobicContact CD2-CG 4.35Å; F323-F418 HydrophobicContact CD2-CZ 4.24Å; F323-F418 HydrophobicContact CE1-CB 3.94Å; F323-F418 AromaticContact CE1-CD2 3.78Å; F323-F418 HydrophobicContact CE1-CD2 3.78Å; F323-F418 HydrophobicContact CE1-CG 4.13Å; F323-F418 AromaticContact CE2-CD2 3.8Å; F323-F418 HydrophobicContact CE2-CD2 3.8Å; F323-F418 HydrophobicContact CE2-CE2 4.01Å; F323-F418 HydrophobicContact CG-CB 4.34Å; F323-F418 HydrophobicContact CG-CD1 4.27Å; F323-F418 AromaticContact CG-CD2 3.26Å; F323-F418 HydrophobicContact CG-CD2 3.26Å; F323-F418 HydrophobicContact CG-CE1 4.42Å; F323-F418 AromaticContact CG-CE2 3.48Å; F323-F418 HydrophobicContact CG-CE2 3.48Å; F323-F418 VanDerWaalsContact CG-CE2 3.48Å; F323-F418 AromaticContact CG-CG 3.71Å; F323-F418 HydrophobicContact CG-CG 3.71Å; F323-F418 HydrophobicContact CG-CZ 4.08Å; F323-F418 AromaticContact CZ-CD2 3.95Å; F323-F418 HydrophobicContact CZ-CD2 3.95Å; L330-F418 HydrophobicContact CD2-CD1 4.04Å; L330-F418 HydrophobicContact CD2-CE1 3.61Å; C363-F418 HydrophobicContact CB-CZ 4.22Å; C363-F418 WeakPolarHBondContact O-CZ 3.33Å; E366-F418 HydrophobicContact CB-CD2 4.14Å; E366-F418 HydrophobicContact CB-CE2 3.79Å; E366-F418 HydrophobicContact CB-CZ 4.13Å; E366-F418 HydrophobicContact CG-CD1 4.48Å; E366-F418 HydrophobicContact CG-CD2 3.54Å; E366-F418 HydrophobicContact CG-CE2 3.74Å; E366-F418 HydrophobicContact CG-CG 3.94Å; E366-F418 HydrophobicContact CG-CZ 4.3Å; T367-F418 WeakPolarHBondContact OG1-CE2 3.27Å; L370-F418 HydrophobicContact CD1-CB 3.95Å; L370-F418 HydrophobicContact CD1-CD2 3.94Å; L370-F418 HydrophobicContact CD1-CG 4.44Å; F418-P420 HydrophobicContact CD1-CG 4.27Å; F418-P420 HydrophobicContact CE1-CG 3.75Å; F418-P420 HydrophobicContact CZ-CG 4.32Å
419R96.1Very high87.5Confident107 Ų10780.4 Ų80.440%0.40440%0.404SS..  trans-132.487.4-173.9-173.3-179.1166.8-164.6-4.3111.6E366 E414 E417 E421 R422E366-R419 PolarHBondContact OE1-N 3.35Å; E414-R419 IonicContact OE2-CZ 3.88Å; E414-R419 IonicContact OE2-NH1 3.04Å; E414-R419 PolarHBondContact OE2-NH1 3.03Å; E417-R419 PolarHBondContact O-N 2.87Å; R419-E421 HydrophobicContact CG-CB 4.42Å; R419-E421 PolarHBondContact O-N 3.1Å; R419-E421 VanDerWaalsContact O-N 3.12Å; R419-R422 WeakPolarHBondContact O-CB 3.36Å; R419-R422 VanDerWaalsContact O-CG 3.22Å; R419-R422 WeakPolarHBondContact O-CG 3.36Å; R419-R422 PolarHBondContact O-N 3.45Å; R419-R422 VanDerWaalsContact O-N 3.08Å
420P96.8Very high86.9Confident2 Ų280.4 Ų80.41%0.01341%0.408CS..G310 helixtrans-55.5-28.9179.4-26.735.9000114.4L330 L359 R362 C363 F418 R422 Y423L330-P420 HydrophobicContact CD1-CG 4.27Å; L330-P420 HydrophobicContact CD2-CG 3.79Å; L359-P420 HydrophobicContact CD1-CB 4.35Å; R362-P420 HydrophobicContact CB-CB 3.82Å; C363-P420 HydrophobicContact CB-CG 4.39Å; C363-P420 VanDerWaalsContact SG-CG 3.58Å; F418-P420 HydrophobicContact CD1-CG 4.27Å; F418-P420 HydrophobicContact CE1-CG 3.75Å; F418-P420 HydrophobicContact CZ-CG 4.32Å; P420-R422 PolarHBondContact O-N 2.86Å; P420-Y423 VanDerWaalsContact O-CD2 3.29Å; P420-Y423 WeakPolarHBondContact O-CD2 3.39Å; P420-Y423 PolarHBondContact O-N 2.91Å
421E94.8Very high86.9Confident44 Ų4475.6 Ų75.621%0.20638%0.382CS..G310 helixtrans-64.3-17.5179.1-68.874.4-166.100113.4R333 R419 Y423 L424R333-E421 IonicContact CZ-OE1 2.8Å; R333-E421 VanDerWaalsContact CZ-OE1 3.23Å; R333-E421 IonicContact NH1-OE1 2.7Å; R333-E421 PolarHBondContact NH1-OE1 3.39Å; R333-E421 IonicContact NH2-OE1 3.88Å; R333-E421 PolarHBondContact NH2-OE1 2.92Å; R419-E421 HydrophobicContact CG-CB 4.42Å; R419-E421 PolarHBondContact O-N 3.1Å; R419-E421 VanDerWaalsContact O-N 3.12Å; E421-Y423 PolarHBondContact O-N 3.43Å; E421-L424 HydrophobicContact CB-CD1 4.25Å; E421-L424 HydrophobicContact CG-CD1 4.39Å; E421-L424 WeakPolarHBondContact O-CB 3.41Å; E421-L424 PolarHBondContact O-N 3.36Å
422R93.5Very high87.1Confident36 Ų3673.8 Ų73.814%0.13637%0.367CS..G310 helixtrans-55.8-28.1178.873.8172.456.8-107.93.3112.8E366 M413 E414 E417 R419 P420 L424E366-R422 IonicContact OE1-CZ 3.08Å; E366-R422 IonicContact OE1-NE 2.79Å; E366-R422 PolarHBondContact OE1-NE 3.1Å; E366-R422 IonicContact OE1-NH2 3.47Å; E366-R422 PolarHBondContact OE1-NH2 3.45Å; E366-R422 WeakPolarHBondContact OE2-CD 3.42Å; E366-R422 IonicContact OE2-NE 3.34Å; E366-R422 PolarHBondContact OE2-NE 3.24Å; M413-R422 PolarHBondContact O-NH1 2.87Å; M413-R422 PolarHBondContact O-NH2 3.09Å; E414-R422 PolarHBondContact O-NH2 2.84Å; E417-R422 PolarHBondContact O-NH2 3.32Å; R419-R422 WeakPolarHBondContact O-CB 3.36Å; R419-R422 VanDerWaalsContact O-CG 3.22Å; R419-R422 WeakPolarHBondContact O-CG 3.36Å; R419-R422 PolarHBondContact O-N 3.45Å; R419-R422 VanDerWaalsContact O-N 3.08Å; P420-R422 PolarHBondContact O-N 2.86Å; R422-L424 VanDerWaalsContact C-N 3.29Å; R422-L424 PolarHBondContact O-N 3.21Å
423Y92.8Very high87.2Confident21 Ų2175.1 Ų75.18%0.08237%0.372CS..G310 helixtrans-82.4-1.5-178.1-54.9-62.8000114.2R362 K365 E366 W412 P420 E421 N425R362-Y423 HydrophobicContact CB-CD2 4.16Å; R362-Y423 HydrophobicContact CG-CD2 4.14Å; K365-Y423 HydrophobicContact CB-CD2 4.33Å; K365-Y423 HydrophobicContact CB-CE2 3.82Å; K365-Y423 HydrophobicContact CD-CD1 3.76Å; K365-Y423 HydrophobicContact CD-CD2 3.91Å; K365-Y423 HydrophobicContact CD-CE1 3.73Å; K365-Y423 HydrophobicContact CD-CE2 3.88Å; K365-Y423 HydrophobicContact CD-CG 3.83Å; K365-Y423 VanDerWaalsContact CE-CE1 3.5Å; K365-Y423 HydrophobicContact CG-CD2 4.34Å; K365-Y423 HydrophobicContact CG-CE1 4.05Å; K365-Y423 HydrophobicContact CG-CE2 3.83Å; K365-Y423 PolarHBondContact O-OH 3.18Å; E366-Y423 HydrophobicContact CB-CE2 3.97Å; E366-Y423 PolarHBondContact OE2-OH 2.57Å; W412-Y423 HydrophobicContact CH2-CE1 4.33Å; W412-Y423 HydrophobicContact CZ3-CE1 4.16Å; P420-Y423 VanDerWaalsContact O-CD2 3.29Å; P420-Y423 WeakPolarHBondContact O-CD2 3.39Å; P420-Y423 PolarHBondContact O-N 2.91Å; E421-Y423 PolarHBondContact O-N 3.43Å; Y423-N425 VanDerWaalsContact C-N 3.27Å
424L89.4Confident87.4Confident111 Ų11167.9 Ų67.958%0.58134%0.337SS*.G310 helixtrans-69.4-28.1173.2-72.2173.8000112.6E421 R422E421-L424 HydrophobicContact CB-CD1 4.25Å; E421-L424 HydrophobicContact CG-CD1 4.39Å; E421-L424 WeakPolarHBondContact O-CB 3.41Å; E421-L424 PolarHBondContact O-N 3.36Å; R422-L424 VanDerWaalsContact C-N 3.29Å; R422-L424 PolarHBondContact O-N 3.21Å
425N77.2Confident87.6Confident131 Ų13163.7 Ų63.770%0.70132%0.318SS*.G310 helixtrans-114.942-176.8-60-29.9000110.5Y423 T427Y423-N425 VanDerWaalsContact C-N 3.27Å; N425-T427 WeakPolarHBondContact O-CG2 3.35Å; N425-T427 PolarHBondContact O-N 3.03Å; N425-T427 VanDerWaalsContact O-N 3.13Å; N425-T427 PolarHBondContact O-OG1 3.26Å
426D66.6Low87.8Confident98 Ų9863.8 Ų63.852%0.52432%0.32SS..  trans-48.2114.9-164.8-155.2-5.1000113.2K365K365-D426 IonicContact NZ-OD2 3.29Å; K365-D426 PolarHBondContact NZ-OD2 3.39Å
427T60.3Low87.8Confident131 Ų13160.1 Ų60.180%0.80431%0.305SS*.  trans-137.312.8-175.838.90000112N425N425-T427 WeakPolarHBondContact O-CG2 3.35Å; N425-T427 PolarHBondContact O-N 3.03Å; N425-T427 VanDerWaalsContact O-N 3.13Å; N425-T427 PolarHBondContact O-OG1 3.26Å
428A66.1Low87.7Confident44 Ų4455.5 Ų55.536%0.36429%0.287SS..  trans-70.2134.8-174.900000112.1W412W412-A428 HydrophobicContact CH2-CB 4.14Å; W412-A428 HydrophobicContact CZ2-CB 4.41Å
429D72.9Confident87.6Confident102 Ų10256.4 Ų56.455%0.54530%0.304SS..  trans-60.5154.3174.5-72.9-39.4000112.7F431 A432D429-F431 VanDerWaalsContact C-N 3.26Å; D429-F431 PolarHBondContact O-N 3.47Å; D429-A432 HydrophobicContact CB-CB 4.05Å; D429-A432 WeakPolarHBondContact O-CB 3.4Å; D429-A432 PolarHBondContact O-N 2.81Å
430K77Confident87.5Confident159 Ų15956.5 Ų56.569%0.69131%0.305SS*.THydrogen-bonded Turntrans-47.4-38.4-170.9-172.7174.9178.7176.70115.4
431F90Very high87.5Confident11 Ų1158 Ų585%0.04831%0.311CS..THydrogen-bonded Turntrans-120.718.3178.7-54.5-59.7000113.6S108 T112 F115 N405 D429 I434 A438S108-F431 PolarHBondContact OG-N 3.34Å; S108-F431 VanDerWaalsContact OG-N 3.1Å; T112-F431 HydrophobicContact CG2-CE2 4.03Å; T112-F431 VanDerWaalsContact OG1-CD2 3.28Å; T112-F431 WeakPolarHBondContact OG1-CD2 3.5Å; T112-F431 VanDerWaalsContact OG1-CE2 3.31Å; T112-F431 WeakPolarHBondContact OG1-CE2 3.35Å; F115-F431 HydrophobicContact CB-CD1 4.5Å; F115-F431 HydrophobicContact CB-CE1 3.97Å; F115-F431 HydrophobicContact CB-CZ 4.06Å; F115-F431 HydrophobicContact CD2-CB 4.37Å; F115-F431 AromaticContact CD2-CD1 3.76Å; F115-F431 HydrophobicContact CD2-CD1 3.76Å; F115-F431 HydrophobicContact CD2-CE1 4.1Å; F115-F431 AromaticContact CD2-CG 3.97Å; F115-F431 HydrophobicContact CD2-CG 3.97Å; F115-F431 HydrophobicContact CE2-CB 4.48Å; F115-F431 HydrophobicContact CE2-CD1 4.4Å; F115-F431 HydrophobicContact CG-CD1 4.36Å; F115-F431 HydrophobicContact CG-CE1 4.29Å; N405-F431 PolarHBondContact ND2-O 3.09Å; D429-F431 VanDerWaalsContact C-N 3.26Å; D429-F431 PolarHBondContact O-N 3.47Å; F431-I434 HydrophobicContact CB-CG2 4.06Å; F431-I434 HydrophobicContact CD1-CG2 4.1Å; F431-A438 HydrophobicContact CD1-CB 4.17Å; F431-A438 HydrophobicContact CE1-CB 3.77Å
432A92.1Very high87.5Confident4 Ų461.8 Ų61.83%0.03332%0.324CS..THydrogen-bonded Turntrans-74-30.5170.200000111.9N405 H406 A411 W412 D429N405-A432 CarbonylContact C-O 3.51Å; H406-A432 WeakPolarHBondContact CA-O 3.34Å; H406-A432 PolarHBondContact CD2-O 2.81Å; H406-A432 PolarHBondContact N-O 3.37Å; A411-A432 HydrophobicContact CB-CB 4.46Å; W412-A432 HydrophobicContact CZ2-CB 4.3Å; D429-A432 HydrophobicContact CB-CB 4.05Å; D429-A432 WeakPolarHBondContact O-CB 3.4Å; D429-A432 PolarHBondContact O-N 2.81Å
433Y95.5Very high87.7Confident46 Ų4662.9 Ų62.918%0.1834%0.336CS..  trans-120.8106.7174.8-172.6-105.3000111.4K365 R369 W412 P435K365-Y433 WeakPolarHBondContact CA-OH 3.26Å; K365-Y433 HydrophobicContact CD-CE1 4.43Å; K365-Y433 HydrophobicContact CG-CE1 3.81Å; K365-Y433 HydrophobicContact CG-CE2 4.26Å; K365-Y433 VanDerWaalsContact CG-CZ 3.49Å; K365-Y433 WeakPolarHBondContact CG-OH 3.41Å; K365-Y433 PolarHBondContact O-OH 2.93Å; R369-Y433 HydrophobicContact CB-CD2 4.23Å; R369-Y433 HydrophobicContact CB-CE2 3.79Å; R369-Y433 HydrophobicContact CG-CD2 4.21Å; R369-Y433 HydrophobicContact CG-CE2 4.29Å; W412-Y433 HydrophobicContact CH2-CD2 4.14Å; W412-Y433 HydrophobicContact CH2-CG 4.43Å; W412-Y433 HydrophobicContact CZ2-CD2 4.32Å; Y433-P435 HydrophobicContact CD1-CG 4.31Å; Y433-P435 HydrophobicContact CE1-CG 3.65Å; Y433-P435 HydrophobicContact CE2-CG 4.03Å; Y433-P435 VanDerWaalsContact CZ-CG 3.5Å
434I96.6Very high87.9Confident6 Ų664.1 Ų64.13%0.03134%0.344CS..  trans-141.142.5-16953.1169.4000114.4F115 M377 V400 P402 N405 H406 F431 F436 G437F115-I434 HydrophobicContact CE2-CD1 3.6Å; F115-I434 HydrophobicContact CE2-CG2 4.3Å; F115-I434 HydrophobicContact CZ-CD1 3.6Å; M377-I434 HydrophobicContact CE-CD1 4.35Å; V400-I434 HydrophobicContact CG1-CD1 3.73Å; P402-I434 HydrophobicContact CB-CG1 4.19Å; P402-I434 HydrophobicContact CG-CD1 4.3Å; P402-I434 HydrophobicContact CG-CG1 4.33Å; N405-I434 HydrophobicContact CB-CD1 4.42Å; H406-I434 VanDerWaalsContact NE2-CG1 3.33Å; H406-I434 WeakPolarHBondContact NE2-CG1 3.24Å; H406-I434 PolarHBondContact NE2-N 3.48Å; F431-I434 HydrophobicContact CB-CG2 4.06Å; F431-I434 HydrophobicContact CD1-CG2 4.1Å; I434-F436 PolarHBondContact O-N 3.19Å; I434-G437 PolarHBondContact O-N 2.75Å; I434-G437 VanDerWaalsContact O-N 3.1Å
435P96.9Very high88.3Confident17 Ų1759.7 Ų59.711%0.1133%0.325CS..THydrogen-bonded Turntrans-63.9-25.1-177.229.3-37.8000113.5L368 Y433L368-P435 HydrophobicContact CB-CB 3.92Å; L368-P435 HydrophobicContact CB-CG 4.25Å; L368-P435 HydrophobicContact CD2-CB 4.39Å; Y433-P435 HydrophobicContact CD1-CG 4.31Å; Y433-P435 HydrophobicContact CE1-CG 3.65Å; Y433-P435 HydrophobicContact CE2-CG 4.03Å; Y433-P435 VanDerWaalsContact CZ-CG 3.5Å
436F97.5Very high89.3Confident34 Ų3455.6 Ų55.615%0.14930%0.301CS..THydrogen-bonded Turntrans-103.211.5177.5-65.4-75.7000113.2L368 I434 C443 E446 A449 Y450L368-F436 HydrophobicContact CD1-CE2 3.63Å; L368-F436 HydrophobicContact CD1-CZ 3.76Å; I434-F436 PolarHBondContact O-N 3.19Å; F436-C443 HydrophobicContact CB-CB 3.88Å; F436-C443 HydrophobicContact CD1-CB 3.92Å; F436-C443 HydrophobicContact CG-CB 4.38Å; F436-C443 WeakPolarHBondContact O-CB 3.38Å; F436-C443 PolarHBondContact O-N 3.43Å; F436-E446 HydrophobicContact CD1-CB 3.93Å; F436-E446 HydrophobicContact CD1-CG 4.21Å; F436-E446 HydrophobicContact CD2-CB 4.27Å; F436-E446 HydrophobicContact CD2-CG 3.65Å; F436-E446 HydrophobicContact CE1-CB 4.18Å; F436-E446 HydrophobicContact CE1-CG 4.31Å; F436-E446 HydrophobicContact CE2-CG 3.8Å; F436-E446 HydrophobicContact CG-CB 3.98Å; F436-E446 HydrophobicContact CG-CG 3.89Å; F436-E446 HydrophobicContact CZ-CB 4.48Å; F436-E446 HydrophobicContact CZ-CG 4.12Å; F436-A449 HydrophobicContact CE1-CB 4.26Å; F436-A449 HydrophobicContact CZ-CB 4.39Å; F436-Y450 HydrophobicContact CE2-CD2 4.49Å; F436-Y450 AromaticContact CE2-CE2 3.7Å; F436-Y450 HydrophobicContact CE2-CE2 3.7Å; F436-Y450 HydrophobicContact CZ-CD2 4.47Å; F436-Y450 HydrophobicContact CZ-CE2 4.06Å
437G96.6Very high90.7Very high13 Ų1355.8 Ų55.813%0.13430%0.302CS..  trans63.2-169.3-173.200000113.2I434I434-G437 PolarHBondContact O-N 2.75Å; I434-G437 VanDerWaalsContact O-N 3.1Å
438A95.8Very high92.5Very high21 Ų2149.9 Ų49.917%0.17427%0.266CS..  trans-148.3175.3177.700000111.5F115 F431F115-A438 HydrophobicContact CB-CB 3.97Å; F115-A438 HydrophobicContact CD1-CB 3.76Å; F115-A438 HydrophobicContact CD2-CB 4.4Å; F115-A438 HydrophobicContact CE1-CB 4.39Å; F115-A438 HydrophobicContact CG-CB 3.78Å; F431-A438 HydrophobicContact CD1-CB 4.17Å; F431-A438 HydrophobicContact CE1-CB 3.77Å
439G94.8Very high94Very high46 Ų4648.2 Ų48.247%0.47425%0.252SS..G310 helixtrans69.2-153.417800000114.2F115 H441 R442F115-G439 WeakPolarHBondContact O-CA 3.45Å; G439-H441 PolarHBondContact O-N 3.47Å; G439-R442 VanDerWaalsContact O-CB 3.29Å; G439-R442 WeakPolarHBondContact O-CB 3.17Å; G439-R442 PolarHBondContact O-N 2.83Å; G439-R442 VanDerWaalsContact O-N 3.09Å
440R93.7Very high95.3Very high110 Ų11045 Ų4542%0.41523%0.232SC..G310 helixtrans-60.1-30-174-65.8174.8176.878.38.9113.6N116 S117 K153N116-R440 PolarHBondContact O-NH1 2.92Å; S117-R440 PolarHBondContact O-NH1 3.09Å; K153-R440 PolarHBondContact NZ-O 3.2Å
441H96.4Very high96.3Very high33 Ų3337.9 Ų37.915%0.15320%0.202CC..G310 helixtrans-99.810.4-178.4-72.8-78.8000113.4N119 A124 E125 N146 R379 G439N119-H441 PolarHBondContact OD1-NE2 3.23Å; A124-H441 VanDerWaalsContact CB-CE1 3.45Å; A124-H441 WeakPolarHBondContact CB-CE1 3.37Å; E125-H441 IonicContact OE1-CE1 3.48Å; N146-H441 PolarHBondContact ND2-CE1 3.49Å; N146-H441 PolarHBondContact ND2-NE2 3.31Å; R379-H441 PolarHBondContact NH2-CD2 2.86Å; R379-H441 VanDerWaalsContact NH2-CG 3.31Å; G439-H441 PolarHBondContact O-N 3.47Å
442R96.7Very high96.7Very high124 Ų12437.3 Ų37.347%0.46820%0.2SC..  trans-52.2144.9174.2-176.6179.1173.1178.41.6111.3K153 G439 E446K153-R442 PolarHBondContact NZ-O 2.8Å; G439-R442 VanDerWaalsContact O-CB 3.29Å; G439-R442 WeakPolarHBondContact O-CB 3.17Å; G439-R442 PolarHBondContact O-N 2.83Å; G439-R442 VanDerWaalsContact O-N 3.09Å; R442-E446 IonicContact CZ-OE2 3.67Å; R442-E446 IonicContact NE-OE2 3.9Å; R442-E446 PolarHBondContact NE-OE2 3.2Å; R442-E446 IonicContact NH2-OE1 3.98Å; R442-E446 IonicContact NH2-OE2 2.63Å; R442-E446 PolarHBondContact NH2-OE2 2.73Å
443C97.8Very high97Very high59 Ų5937.4 Ų37.440%0.39920%0.2SC..  trans-58.7140.9174.9-167.10000111.6F436 G445F436-C443 HydrophobicContact CB-CB 3.88Å; F436-C443 HydrophobicContact CD1-CB 3.92Å; F436-C443 HydrophobicContact CG-CB 4.38Å; F436-C443 WeakPolarHBondContact O-CB 3.38Å; F436-C443 PolarHBondContact O-N 3.43Å; C443-G445 PolarHBondContact SG-N 3.18Å
444I96.9Very high97.2Very high47 Ų4735.4 Ų35.424%0.24119%0.192CC..SBendtrans-97.1-16.2172.560.5171.7000112.5K153 L156 L160K153-I444 HydrophobicContact CB-CG2 4.4Å; L156-I444 HydrophobicContact CB-CD1 3.51Å; L156-I444 HydrophobicContact CD1-CD1 4.14Å; L156-I444 HydrophobicContact CG-CD1 4.49Å; L160-I444 HydrophobicContact CD1-CD1 4.4Å; L160-I444 HydrophobicContact CD1-CG1 4.28Å
445G96.9Very high97.3Very high18 Ų1835.1 Ų35.119%0.18619%0.19CC..  trans-91.88.4-175.400000114.8C443 N447 F448 A449C443-G445 PolarHBondContact SG-N 3.18Å; G445-N447 PolarHBondContact O-N 3.17Å; G445-F448 PolarHBondContact O-N 3.41Å; G445-A449 WeakPolarHBondContact O-CB 3.45Å; G445-A449 PolarHBondContact O-N 3.12Å
446E97.7Very high97.4Very high44 Ų4434.3 Ų34.321%0.20619%0.185CC..Hα-helixtrans-53.4-54.4-177.7177.6171.3-177.300111.8F436 R442 F448 A449 Y450F436-E446 HydrophobicContact CD1-CB 3.93Å; F436-E446 HydrophobicContact CD1-CG 4.21Å; F436-E446 HydrophobicContact CD2-CB 4.27Å; F436-E446 HydrophobicContact CD2-CG 3.65Å; F436-E446 HydrophobicContact CE1-CB 4.18Å; F436-E446 HydrophobicContact CE1-CG 4.31Å; F436-E446 HydrophobicContact CE2-CG 3.8Å; F436-E446 HydrophobicContact CG-CB 3.98Å; F436-E446 HydrophobicContact CG-CG 3.89Å; F436-E446 HydrophobicContact CZ-CB 4.48Å; F436-E446 HydrophobicContact CZ-CG 4.12Å; R442-E446 IonicContact CZ-OE2 3.67Å; R442-E446 IonicContact NE-OE2 3.9Å; R442-E446 PolarHBondContact NE-OE2 3.2Å; R442-E446 IonicContact NH2-OE1 3.98Å; R442-E446 IonicContact NH2-OE2 2.63Å; R442-E446 PolarHBondContact NH2-OE2 2.73Å; E446-F448 VanDerWaalsContact C-N 3.31Å; E446-F448 PolarHBondContact O-N 2.82Å; E446-A449 PolarHBondContact O-N 3.36Å; E446-A449 VanDerWaalsContact O-N 3.15Å; E446-Y450 HydrophobicContact CG-CD2 4.22Å; E446-Y450 HydrophobicContact CG-CE2 4.14Å; E446-Y450 WeakPolarHBondContact O-CD2 3.42Å; E446-Y450 PolarHBondContact O-N 2.74Å
447N97.3Very high97.5Very high102 Ų10232.7 Ų32.755%0.54518%0.178SC..Hα-helixtrans-60.5-40.4179.3-65.8-14.5000112.3F165 G445 Y450 V451F165-N447 HydrophobicContact CE2-CB 3.66Å; F165-N447 HydrophobicContact CZ-CB 3.82Å; G445-N447 PolarHBondContact O-N 3.17Å; N447-Y450 PolarHBondContact O-N 2.69Å; N447-V451 WeakPolarHBondContact O-CG2 3.45Å; N447-V451 PolarHBondContact O-N 3.03Å
448F97.6Very high97.6Very high8 Ų832.1 Ų32.14%0.03517%0.172CC..Hα-helixtrans-63.7-42.7176.8175.6-98.4000111.7L160 F165 H168 C206 L207 G445 E446 Y450 V451 Q452L160-F448 HydrophobicContact CD2-CB 4.18Å; L160-F448 HydrophobicContact CD2-CG 4.48Å; F165-F448 HydrophobicContact CE1-CB 3.9Å; F165-F448 HydrophobicContact CE1-CD2 4.16Å; F165-F448 HydrophobicContact CZ-CB 4.35Å; H168-F448 AromaticContact ND1-CD2 3.78Å; H168-F448 AromaticContact ND1-CE2 3.75Å; C206-F448 HydrophobicContact CB-CE2 3.68Å; C206-F448 HydrophobicContact CB-CZ 4.09Å; L207-F448 HydrophobicContact CD1-CD1 4.22Å; L207-F448 HydrophobicContact CD1-CE1 3.69Å; L207-F448 HydrophobicContact CD1-CE2 4.43Å; L207-F448 HydrophobicContact CD1-CZ 3.81Å; L207-F448 HydrophobicContact CD2-CD2 3.96Å; L207-F448 HydrophobicContact CD2-CE1 4.38Å; L207-F448 HydrophobicContact CD2-CE2 3.77Å; L207-F448 HydrophobicContact CD2-CG 4.34Å; L207-F448 HydrophobicContact CD2-CZ 3.99Å; L207-F448 HydrophobicContact CG-CE1 4.22Å; L207-F448 HydrophobicContact CG-CE2 4.07Å; L207-F448 HydrophobicContact CG-CZ 3.82Å; G445-F448 PolarHBondContact O-N 3.41Å; E446-F448 VanDerWaalsContact C-N 3.31Å; E446-F448 PolarHBondContact O-N 2.82Å; F448-Y450 PolarHBondContact O-N 3.4Å; F448-V451 PolarHBondContact O-N 3.05Å; F448-Q452 HydrophobicContact CE1-CB 4.28Å; F448-Q452 HydrophobicContact CZ-CB 4.33Å; F448-Q452 WeakPolarHBondContact O-CB 3.46Å; F448-Q452 PolarHBondContact O-N 3.09Å
449A98.3Very high97.7Very high9 Ų931.3 Ų31.37%0.07417%0.165CC..Hα-helixtrans-61.7-42.7177.800000111.5F436 G445 E446 Q452 I453F436-A449 HydrophobicContact CE1-CB 4.26Å; F436-A449 HydrophobicContact CZ-CB 4.39Å; G445-A449 WeakPolarHBondContact O-CB 3.45Å; G445-A449 PolarHBondContact O-N 3.12Å; E446-A449 PolarHBondContact O-N 3.36Å; E446-A449 VanDerWaalsContact O-N 3.15Å; A449-Q452 PolarHBondContact O-N 3.23Å; A449-I453 WeakPolarHBondContact O-CB 3.25Å; A449-I453 WeakPolarHBondContact O-CG1 3.4Å; A449-I453 PolarHBondContact O-N 3.38Å
450Y98.6Very high97.9Very high33 Ų3329.1 Ų29.113%0.12914%0.142CC..Hα-helixtrans-62.7-44.7173.7-85-91.8000111.9E361 L364 F436 E446 N447 F448 Q452 K454E361-Y450 HydrophobicContact CG-CD1 4.28Å; E361-Y450 HydrophobicContact CG-CE1 3.96Å; L364-Y450 HydrophobicContact CB-CE1 4.4Å; L364-Y450 HydrophobicContact CD2-CD1 3.51Å; L364-Y450 HydrophobicContact CD2-CE1 3.75Å; L364-Y450 HydrophobicContact CD2-CG 4.1Å; L364-Y450 HydrophobicContact CG-CD1 4.25Å; L364-Y450 HydrophobicContact CG-CE1 3.95Å; F436-Y450 HydrophobicContact CE2-CD2 4.49Å; F436-Y450 AromaticContact CE2-CE2 3.7Å; F436-Y450 HydrophobicContact CE2-CE2 3.7Å; F436-Y450 HydrophobicContact CZ-CD2 4.47Å; F436-Y450 HydrophobicContact CZ-CE2 4.06Å; E446-Y450 HydrophobicContact CG-CD2 4.22Å; E446-Y450 HydrophobicContact CG-CE2 4.14Å; E446-Y450 WeakPolarHBondContact O-CD2 3.42Å; E446-Y450 PolarHBondContact O-N 2.74Å; N447-Y450 PolarHBondContact O-N 2.69Å; F448-Y450 PolarHBondContact O-N 3.4Å; Y450-Q452 PolarHBondContact O-N 3.37Å; Y450-K454 HydrophobicContact CD1-CD 4.28Å; Y450-K454 WeakPolarHBondContact O-CB 3.27Å; Y450-K454 WeakPolarHBondContact O-CG 3.05Å; Y450-K454 PolarHBondContact O-N 3.19Å
451V98.6Very high98.1Very high10 Ų1023.9 Ų23.96%0.06112%0.123CC..Hα-helixtrans-59.5-47.5176170.10000111F165 H168 V169 I172 F351 N447 F448 T455F165-V451 HydrophobicContact CB-CG2 4.17Å; F165-V451 HydrophobicContact CD1-CG2 4.4Å; F165-V451 HydrophobicContact CD2-CG2 4.46Å; F165-V451 HydrophobicContact CG-CG2 4.11Å; H168-V451 HydrophobicContact CB-CG1 4.36Å; V169-V451 HydrophobicContact CG2-CG1 3.96Å; I172-V451 HydrophobicContact CD1-CG1 4.16Å; F351-V451 HydrophobicContact CD2-CG2 4.09Å; F351-V451 HydrophobicContact CE2-CG2 3.65Å; N447-V451 WeakPolarHBondContact O-CG2 3.45Å; N447-V451 PolarHBondContact O-N 3.03Å; F448-V451 PolarHBondContact O-N 3.05Å; V451-T455 VanDerWaalsContact O-CB 3.26Å; V451-T455 WeakPolarHBondContact O-CB 3.46Å; V451-T455 PolarHBondContact O-N 3.12Å; V451-T455 PolarHBondContact O-OG1 2.83Å
452Q98.7Very high98.2Very high0 Ų023.5 Ų23.50%012%0.12CC..Hα-helixtrans-64-54.4-178.3-173.2178.549.200111.5I172 T202 S313 F448 A449 Y450 T455 I456I172-Q452 HydrophobicContact CD1-CB 4.24Å; I172-Q452 HydrophobicContact CD1-CG 4.41Å; T202-Q452 PolarHBondContact OG1-NE2 2.81Å; S313-Q452 VanDerWaalsContact CB-OE1 3.26Å; S313-Q452 PolarHBondContact OG-OE1 3.32Å; F448-Q452 HydrophobicContact CE1-CB 4.28Å; F448-Q452 HydrophobicContact CZ-CB 4.33Å; F448-Q452 WeakPolarHBondContact O-CB 3.46Å; F448-Q452 PolarHBondContact O-N 3.09Å; A449-Q452 PolarHBondContact O-N 3.23Å; Y450-Q452 PolarHBondContact O-N 3.37Å; Q452-T455 PolarHBondContact O-N 2.87Å; Q452-I456 HydrophobicContact CG-CD1 3.92Å; Q452-I456 VanDerWaalsContact O-CG1 3.26Å; Q452-I456 WeakPolarHBondContact O-CG1 3.29Å; Q452-I456 PolarHBondContact O-N 2.95Å
453I98.9Very high98.3Very high5 Ų519.3 Ų19.33%0.02611%0.107CC..Hα-helixtrans-69.5-41.3-174.6-59.6169.2000110.8T316 L320 L364 A449 I456 W457T316-I453 HydrophobicContact CG2-CD1 3.94Å; L320-I453 HydrophobicContact CD2-CG2 4.24Å; L364-I453 HydrophobicContact CD1-CB 4.37Å; L364-I453 HydrophobicContact CD1-CD1 3.99Å; L364-I453 HydrophobicContact CD1-CG2 3.73Å; L364-I453 HydrophobicContact CD2-CB 3.92Å; L364-I453 HydrophobicContact CD2-CD1 4.43Å; L364-I453 HydrophobicContact CD2-CG2 3.9Å; L364-I453 HydrophobicContact CG-CG2 4.43Å; A449-I453 WeakPolarHBondContact O-CB 3.25Å; A449-I453 WeakPolarHBondContact O-CG1 3.4Å; A449-I453 PolarHBondContact O-N 3.38Å; I453-I456 PolarHBondContact O-N 3.35Å; I453-W457 WeakPolarHBondContact O-CB 3.44Å; I453-W457 PolarHBondContact O-N 3.09Å
454K98.8Very high98.3Very high5 Ų516.6 Ų16.62%0.0229%0.088CC..Hα-helixtrans-65.5-42.9176.9-67.7-18082170.30111.3L354 L357 L360 E361 L364 Y450 W457 S458L354-K454 HydrophobicContact CD2-CB 4.28Å; L354-K454 VanDerWaalsContact O-CE 3.25Å; L354-K454 WeakPolarHBondContact O-CE 3.17Å; L354-K454 PolarHBondContact O-NZ 3.35Å; L357-K454 WeakPolarHBondContact O-CE 3.34Å; L357-K454 PolarHBondContact O-NZ 3.23Å; L357-K454 VanDerWaalsContact O-NZ 3.07Å; L360-K454 HydrophobicContact CD2-CB 4.28Å; L360-K454 HydrophobicContact CD2-CG 4.45Å; E361-K454 IonicContact OE2-NZ 3.42Å; E361-K454 PolarHBondContact OE2-NZ 2.96Å; L364-K454 HydrophobicContact CD2-CG 4.17Å; Y450-K454 HydrophobicContact CD1-CD 4.28Å; Y450-K454 WeakPolarHBondContact O-CB 3.27Å; Y450-K454 WeakPolarHBondContact O-CG 3.05Å; Y450-K454 PolarHBondContact O-N 3.19Å; K454-W457 PolarHBondContact O-N 3.16Å; K454-S458 WeakPolarHBondContact O-CB 3.4Å; K454-S458 PolarHBondContact O-N 3.48Å; K454-S458 PolarHBondContact O-OG 3.21Å
455T98.9Very high98.4Very high0 Ų016.2 Ų16.20%09%0.085CC..Hα-helixtrans-61-50.2176.6-52.60000111V169 I172 E173 L349 L354 V451 Q452 W457 S458 T459V169-T455 HydrophobicContact CG1-CG2 4.14Å; I172-T455 HydrophobicContact CB-CG2 3.81Å; I172-T455 HydrophobicContact CG2-CG2 3.63Å; E173-T455 HydrophobicContact CB-CG2 4.03Å; L349-T455 HydrophobicContact CD1-CG2 3.99Å; L354-T455 WeakPolarHBondContact CD1-OG1 3.28Å; V451-T455 VanDerWaalsContact O-CB 3.26Å; V451-T455 WeakPolarHBondContact O-CB 3.46Å; V451-T455 PolarHBondContact O-N 3.12Å; V451-T455 PolarHBondContact O-OG1 2.83Å; Q452-T455 PolarHBondContact O-N 2.87Å; T455-W457 PolarHBondContact O-N 3.41Å; T455-S458 PolarHBondContact O-N 2.71Å; T455-T459 PolarHBondContact O-N 2.96Å; T455-T459 PolarHBondContact O-OG1 2.92Å
456I98.9Very high98.5Very high0 Ų015.3 Ų15.30%08%0.076CC..Hα-helixtrans-56.5-51.1178.7-68.9169.4000110.6I172 T176 L195 L198 I199 Q452 I453 T459 L460I172-I456 HydrophobicContact CG2-CD1 4.36Å; I172-I456 HydrophobicContact CG2-CG1 3.6Å; T176-I456 HydrophobicContact CG2-CG2 4.43Å; L195-I456 HydrophobicContact CD2-CG2 3.88Å; L198-I456 HydrophobicContact CD2-CD1 4.26Å; L198-I456 HydrophobicContact CD2-CG1 4.21Å; L198-I456 HydrophobicContact CD2-CG2 4.06Å; I199-I456 HydrophobicContact CD1-CD1 4.16Å; I199-I456 HydrophobicContact CG1-CD1 3.62Å; Q452-I456 HydrophobicContact CG-CD1 3.92Å; Q452-I456 VanDerWaalsContact O-CG1 3.26Å; Q452-I456 WeakPolarHBondContact O-CG1 3.29Å; Q452-I456 PolarHBondContact O-N 2.95Å; I453-I456 PolarHBondContact O-N 3.35Å; I456-T459 PolarHBondContact O-N 2.92Å; I456-L460 HydrophobicContact CG2-CD1 3.86Å; I456-L460 HydrophobicContact CG2-CG 4.3Å; I456-L460 WeakPolarHBondContact O-CB 3.36Å; I456-L460 VanDerWaalsContact O-CG 3.3Å; I456-L460 WeakPolarHBondContact O-CG 3.44Å; I456-L460 PolarHBondContact O-N 2.86Å
457W98.9Very high98.5Very high0 Ų015.5 Ų15.50%08%0.077CC..Hα-helixtrans-72.8-32.5-176.6-85.797.3000114L191 L195 S317 L320 G321 L324 L360 I453 K454 T455 L460 L461 F466L191-W457 HydrophobicContact CD2-CH2 4.17Å; L191-W457 HydrophobicContact CD2-CZ2 4.24Å; L195-W457 HydrophobicContact CD1-CZ2 4.34Å; S317-W457 VanDerWaalsContact O-CE2 3.27Å; S317-W457 WeakPolarHBondContact O-CZ2 3.43Å; S317-W457 PolarHBondContact O-NE1 2.88Å; L320-W457 HydrophobicContact CD2-CB 4.23Å; L320-W457 VanDerWaalsContact CD2-CD1 3.49Å; L320-W457 HydrophobicContact CD2-CD2 4.08Å; L320-W457 HydrophobicContact CD2-CG 3.63Å; L320-W457 HydrophobicContact CG-CD2 4.17Å; L320-W457 HydrophobicContact CG-CG 4.25Å; G321-W457 VanDerWaalsContact N-CZ2 3.3Å; L324-W457 HydrophobicContact CD1-CE3 4.03Å; L324-W457 HydrophobicContact CD1-CZ3 4.32Å; L360-W457 HydrophobicContact CD1-CB 4.18Å; I453-W457 WeakPolarHBondContact O-CB 3.44Å; I453-W457 PolarHBondContact O-N 3.09Å; K454-W457 PolarHBondContact O-N 3.16Å; T455-W457 PolarHBondContact O-N 3.41Å; W457-L460 HydrophobicContact CD2-CD1 4.41Å; W457-L460 HydrophobicContact CE3-CB 4.22Å; W457-L460 HydrophobicContact CE3-CD1 4.39Å; W457-L460 HydrophobicContact CH2-CD1 4.29Å; W457-L460 HydrophobicContact CZ2-CD1 4.35Å; W457-L460 HydrophobicContact CZ3-CB 4.39Å; W457-L460 HydrophobicContact CZ3-CD1 4.35Å; W457-L460 PolarHBondContact O-N 2.79Å; W457-L461 HydrophobicContact CE3-CG 4.44Å; W457-L461 VanDerWaalsContact O-CB 3.32Å; W457-L461 WeakPolarHBondContact O-CB 3.46Å; W457-L461 WeakPolarHBondContact O-CG 3.26Å; W457-L461 PolarHBondContact O-N 3.45Å; W457-F466 HydrophobicContact CH2-CE2 4.44Å; W457-F466 HydrophobicContact CZ3-CD2 4.05Å; W457-F466 AromaticContact CZ3-CE2 3.89Å; W457-F466 HydrophobicContact CZ3-CE2 3.89Å; W457-F466 HydrophobicContact CZ3-CZ 4.47Å
458S98.9Very high98.6Very high0 Ų011.8 Ų11.80%06%0.057CC..Hα-helixtrans-59.1-48.7169.1-72.20000110.5Q338 L357 L360 K454 T455 L461 R462Q338-S458 PolarHBondContact NE2-OG 3.38Å; Q338-S458 VanDerWaalsContact OE1-CB 3.31Å; Q338-S458 PolarHBondContact OE1-OG 3.45Å; L357-S458 VanDerWaalsContact CD1-OG 3.26Å; L357-S458 WeakPolarHBondContact CD1-OG 3.42Å; L360-S458 VanDerWaalsContact CD2-OG 3.29Å; L360-S458 WeakPolarHBondContact CD2-OG 3.49Å; K454-S458 WeakPolarHBondContact O-CB 3.4Å; K454-S458 PolarHBondContact O-N 3.48Å; K454-S458 PolarHBondContact O-OG 3.21Å; T455-S458 PolarHBondContact O-N 2.71Å; S458-L461 PolarHBondContact O-N 3.17Å; S458-R462 VanDerWaalsContact O-CG 3.24Å; S458-R462 WeakPolarHBondContact O-CG 3.16Å; S458-R462 PolarHBondContact O-N 2.99Å; S458-R462 VanDerWaalsContact O-N 3.17Å
459T98.8Very high98.6Very high5 Ų512.4 Ų12.43%0.0316%0.061CC..Hα-helixtrans-61.8-45.3176.4-55.50000111.7T176 V177 T455 I456 L461 R462 L463T176-T459 HydrophobicContact CG2-CG2 3.7Å; V177-T459 HydrophobicContact CG2-CG2 3.65Å; T455-T459 PolarHBondContact O-N 2.96Å; T455-T459 PolarHBondContact O-OG1 2.92Å; I456-T459 PolarHBondContact O-N 2.92Å; T459-L461 PolarHBondContact O-N 3.17Å; T459-R462 WeakPolarHBondContact O-CB 3.47Å; T459-R462 PolarHBondContact O-N 2.87Å; T459-L463 HydrophobicContact CG2-CD1 3.97Å; T459-L463 HydrophobicContact CG2-CG 4.42Å; T459-L463 WeakPolarHBondContact O-CG 3.49Å; T459-L463 PolarHBondContact O-N 2.65Å
460L98.8Very high98.6Very high0 Ų019 Ų190%010%0.095CC..Hα-helixtrans-64.4-40.3-180-73-178.7000113.3T176 F180 L195 I456 W457 R462 L463 Y464 F466T176-L460 HydrophobicContact CG2-CD2 4.32Å; T176-L460 HydrophobicContact CG2-CG 4.37Å; F180-L460 HydrophobicContact CD1-CD2 3.9Å; F180-L460 HydrophobicContact CD2-CD2 3.6Å; F180-L460 HydrophobicContact CE1-CD2 3.85Å; F180-L460 HydrophobicContact CE2-CD1 4.3Å; F180-L460 HydrophobicContact CE2-CD2 3.57Å; F180-L460 HydrophobicContact CE2-CG 4.37Å; F180-L460 HydrophobicContact CG-CD2 3.78Å; F180-L460 HydrophobicContact CZ-CD1 4.19Å; F180-L460 HydrophobicContact CZ-CD2 3.7Å; L195-L460 HydrophobicContact CD2-CD1 4.17Å; I456-L460 HydrophobicContact CG2-CD1 3.86Å; I456-L460 HydrophobicContact CG2-CG 4.3Å; I456-L460 WeakPolarHBondContact O-CB 3.36Å; I456-L460 VanDerWaalsContact O-CG 3.3Å; I456-L460 WeakPolarHBondContact O-CG 3.44Å; I456-L460 PolarHBondContact O-N 2.86Å; W457-L460 HydrophobicContact CD2-CD1 4.41Å; W457-L460 HydrophobicContact CE3-CB 4.22Å; W457-L460 HydrophobicContact CE3-CD1 4.39Å; W457-L460 HydrophobicContact CH2-CD1 4.29Å; W457-L460 HydrophobicContact CZ2-CD1 4.35Å; W457-L460 HydrophobicContact CZ3-CB 4.39Å; W457-L460 HydrophobicContact CZ3-CD1 4.35Å; W457-L460 PolarHBondContact O-N 2.79Å; L460-R462 VanDerWaalsContact C-N 3.27Å; L460-R462 PolarHBondContact O-N 2.92Å; L460-L463 PolarHBondContact O-N 2.9Å; L460-Y464 HydrophobicContact CD2-CD2 4.39Å; L460-Y464 PolarHBondContact O-N 3.05Å; L460-F466 HydrophobicContact CB-CE2 4.03Å; L460-F466 HydrophobicContact CB-CZ 4.12Å; L460-F466 HydrophobicContact CD1-CZ 4.47Å; L460-F466 HydrophobicContact CD2-CZ 4.32Å
461L98.6Very high98.5Very high0 Ų020.3 Ų20.30%012%0.119CC..Hα-helixtrans-66.3-29.2176.1-73.7169.4000112.6L324 Q331 C334 Y335 L360 W457 S458 T459 R495L324-L461 HydrophobicContact CD1-CD2 4.34Å; Q331-L461 HydrophobicContact CG-CD2 3.67Å; C334-L461 HydrophobicContact CB-CD1 3.75Å; Y335-L461 VanDerWaalsContact CD2-O 3.3Å; Y335-L461 WeakPolarHBondContact CD2-O 3.42Å; L360-L461 HydrophobicContact CD1-CD1 4.25Å; W457-L461 HydrophobicContact CE3-CG 4.44Å; W457-L461 VanDerWaalsContact O-CB 3.32Å; W457-L461 WeakPolarHBondContact O-CB 3.46Å; W457-L461 WeakPolarHBondContact O-CG 3.26Å; W457-L461 PolarHBondContact O-N 3.45Å; S458-L461 PolarHBondContact O-N 3.17Å; T459-L461 PolarHBondContact O-N 3.17Å; L461-R495 WeakPolarHBondContact O-CD 3.5Å; L461-R495 PolarHBondContact O-NE 2.79Å
462R98.2Very high98.5Very high25 Ų2523.5 Ų23.59%0.09413%0.13CC..Hα-helixtrans-73.4-36.8172.3-66.4171.4-175.6-154.8-2.4112C342 L346 P347 S458 T459 L460C342-R462 PolarHBondContact SG-NH2 3Å; L346-R462 HydrophobicContact CD1-CG 4.17Å; L346-R462 HydrophobicContact CD2-CG 4.39Å; L346-R462 PolarHBondContact O-NH1 3.34Å; P347-R462 PolarHBondContact O-NH1 3.16Å; S458-R462 VanDerWaalsContact O-CG 3.24Å; S458-R462 WeakPolarHBondContact O-CG 3.16Å; S458-R462 PolarHBondContact O-N 2.99Å; S458-R462 VanDerWaalsContact O-N 3.17Å; T459-R462 WeakPolarHBondContact O-CB 3.47Å; T459-R462 PolarHBondContact O-N 2.87Å; L460-R462 VanDerWaalsContact C-N 3.27Å; L460-R462 PolarHBondContact O-N 2.92Å
463L98.1Very high98.4Very high36 Ų3625.5 Ų25.519%0.18814%0.139CC..Hα-helixtrans-79.2-42.9-177.8-70.4174.9000113F180 T459 L460 R494 R495F180-L463 HydrophobicContact CB-CD1 4.23Å; T459-L463 HydrophobicContact CG2-CD1 3.97Å; T459-L463 HydrophobicContact CG2-CG 4.42Å; T459-L463 WeakPolarHBondContact O-CG 3.49Å; T459-L463 PolarHBondContact O-N 2.65Å; L460-L463 PolarHBondContact O-N 2.9Å; L463-R494 WeakPolarHBondContact O-CA 3.46Å; L463-R495 PolarHBondContact O-N 2.74Å
464Y98.7Very high98.4Very high1 Ų125.3 Ų25.30%0.00414%0.138CC..EExtended strand (participates in β ladder)trans-136.6156.9-165.8-59.1-66.9000113.2F180 G184 L460 F466 Y492 K493 R494F180-Y464 HydrophobicContact CB-CE2 4.1Å; F180-Y464 HydrophobicContact CD1-CE2 4.03Å; F180-Y464 HydrophobicContact CG-CE2 4.39Å; F180-Y464 PolarHBondContact O-OH 3.11Å; G184-Y464 PolarHBondContact O-OH 2.85Å; L460-Y464 HydrophobicContact CD2-CD2 4.39Å; L460-Y464 PolarHBondContact O-N 3.05Å; Y464-F466 HydrophobicContact CD2-CZ 4.15Å; Y464-F466 HydrophobicContact CG-CZ 4.37Å; Y464-Y492 AromaticContact CD1-CD2 3.64Å; Y464-Y492 HydrophobicContact CD1-CD2 3.64Å; Y464-Y492 HydrophobicContact CD1-CE2 4.44Å; Y464-Y492 AromaticContact CE1-CD2 3.69Å; Y464-Y492 HydrophobicContact CE1-CD2 3.69Å; Y464-Y492 HydrophobicContact CE1-CE2 4.04Å; Y464-Y492 HydrophobicContact CG-CD2 4.21Å; Y464-K493 CarbonylContact C-O 3.55Å; Y464-K493 VanDerWaalsContact CA-O 3.28Å; Y464-K493 WeakPolarHBondContact CA-O 3.36Å; Y464-R494 HydrophobicContact CD1-CB 4.47Å
465E98.6Very high98.3Very high39 Ų3929 Ų2918%0.18216%0.161CC..EExtended strand (participates in β ladder)trans-106.1132.3159.1-169-164.4138.300108.4K328 Y492 K493K328-E465 IonicContact NZ-OE1 3.22Å; K328-E465 PolarHBondContact NZ-OE1 3.45Å; E465-Y492 WeakPolarHBondContact O-CA 3.2Å; E465-K493 HydrophobicContact CB-CG 4.14Å; E465-K493 VanDerWaalsContact CD-NZ 3.28Å; E465-K493 PolarHBondContact N-O 3.07Å; E465-K493 PolarHBondContact O-N 3.02Å; E465-K493 WeakPolarHBondContact OE1-CE 3.44Å; E465-K493 IonicContact OE1-NZ 2.71Å; E465-K493 PolarHBondContact OE1-NZ 3.45Å; E465-K493 WeakPolarHBondContact OE2-CE 3.49Å; E465-K493 IonicContact OE2-NZ 2.89Å; E465-K493 PolarHBondContact OE2-NZ 3.09Å; E465-K493 VanDerWaalsContact OE2-NZ 3.1Å
466F98.6Very high98.2Very high0 Ų030.6 Ų30.60%017%0.169CC..EExtended strand (participates in β ladder)trans-108.9141.1-174.9-64.2-85.3000112.4W183 A325 K328 Q331 W457 L460 Y464 I490 R491W183-F466 HydrophobicContact CZ3-CE1 4.16Å; A325-F466 HydrophobicContact CB-CB 4.11Å; K328-F466 WeakPolarHBondContact CE-O 3.43Å; K328-F466 PolarHBondContact NZ-O 3.13Å; Q331-F466 PolarHBondContact NE2-O 3.32Å; W457-F466 HydrophobicContact CH2-CE2 4.44Å; W457-F466 HydrophobicContact CZ3-CD2 4.05Å; W457-F466 AromaticContact CZ3-CE2 3.89Å; W457-F466 HydrophobicContact CZ3-CE2 3.89Å; W457-F466 HydrophobicContact CZ3-CZ 4.47Å; L460-F466 HydrophobicContact CB-CE2 4.03Å; L460-F466 HydrophobicContact CB-CZ 4.12Å; L460-F466 HydrophobicContact CD1-CZ 4.47Å; L460-F466 HydrophobicContact CD2-CZ 4.32Å; Y464-F466 HydrophobicContact CD2-CZ 4.15Å; Y464-F466 HydrophobicContact CG-CZ 4.37Å; F466-I490 HydrophobicContact CB-CD1 3.87Å; F466-I490 HydrophobicContact CB-CG1 4.34Å; F466-I490 HydrophobicContact CD1-CD1 3.85Å; F466-I490 HydrophobicContact CD1-CG1 4.24Å; F466-I490 HydrophobicContact CD1-CG2 4.06Å; F466-I490 HydrophobicContact CE1-CG2 4.44Å; F466-I490 HydrophobicContact CG-CD1 4.17Å; F466-R491 CarbonylContact C-O 3.51Å; F466-R491 WeakPolarHBondContact CA-O 3.35Å
467E98.6Very high97.9Very high48 Ų4832.7 Ų32.722%0.22418%0.18CC..EExtended strand (participates in β ladder)trans-132.5148.2-178.7-72.9173.9-16000111K328 I490 R491 K493K328-E467 IonicContact NZ-OE1 2.68Å; E467-I490 WeakPolarHBondContact O-CG1 3.17Å; E467-R491 HydrophobicContact CB-CB 4.01Å; E467-R491 HydrophobicContact CB-CG 4.37Å; E467-R491 PolarHBondContact N-O 3.31Å; E467-R491 PolarHBondContact O-N 2.88Å; E467-R491 IonicContact OE2-NH1 3.92Å; E467-K493 IonicContact OE1-NZ 2.96Å; E467-K493 PolarHBondContact OE1-NZ 2.83Å
468L98.6Very high97.4Very high23 Ų2335 Ų3512%0.1219%0.19CC..EExtended strand (participates in β ladder)trans-69.1139.9165.7-58.4-175.5000109.7F322 A325 Q326 D470 F473F322-L468 HydrophobicContact CD1-CD2 3.79Å; A325-L468 HydrophobicContact CB-CD2 3.87Å; A325-L468 HydrophobicContact CB-CG 4.33Å; Q326-L468 HydrophobicContact CB-CD1 3.96Å; Q326-L468 HydrophobicContact CB-CG 4.49Å; Q326-L468 HydrophobicContact CG-CD1 4.11Å; L468-D470 PolarHBondContact O-N 2.89Å; L468-F473 HydrophobicContact CD1-CB 4.39Å
469V98.4Very high96.5Very high22 Ų2240 Ų4013%0.13322%0.22CC..G310 helixtrans-77.2118.1171179.90000107.7E188 G471 Y472 I489 R491E188-V469 HydrophobicContact CG-CG2 4.06Å; V469-G471 PolarHBondContact O-N 2.95Å; V469-Y472 VanDerWaalsContact O-CB 3.26Å; V469-Y472 WeakPolarHBondContact O-CB 3.25Å; V469-Y472 PolarHBondContact O-N 2.97Å; V469-I489 HydrophobicContact CG2-CG2 4.12Å; V469-R491 HydrophobicContact CG2-CB 4.05Å
470D96.8Very high95.4Very high147 Ų14742.6 Ų42.679%0.78624%0.236SC*.G310 helixtrans51.931179.1-52.3-28.1000114.4L468 Y472 R491L468-D470 PolarHBondContact O-N 2.89Å; D470-Y472 PolarHBondContact O-N 2.75Å; D470-R491 IonicContact OD1-NH2 2.83Å
471G96.8Very high94.3Very high60 Ų6046.1 Ų46.162%0.61925%0.254SS*.G310 helixtrans70.79.1-177.300000114.7V469 F473V469-G471 PolarHBondContact O-N 2.95Å; G471-F473 PolarHBondContact O-N 3.36Å
472Y98.2Very high93.8Very high77 Ų7747.9 Ų47.930%0.30226%0.262SS..PPolyproline II helixtrans-71.2117.5179.2178.2-106.5000111.6V469 D470 P474 H486 N487V469-Y472 VanDerWaalsContact O-CB 3.26Å; V469-Y472 WeakPolarHBondContact O-CB 3.25Å; V469-Y472 PolarHBondContact O-N 2.97Å; D470-Y472 PolarHBondContact O-N 2.75Å; Y472-P474 HydrophobicContact CE1-CB 4.42Å; Y472-P474 HydrophobicContact CE1-CG 4.24Å; Y472-H486 PolarHBondContact OH-O 3.47Å; Y472-N487 HydrophobicContact CE1-CB 3.93Å; Y472-N487 WeakPolarHBondContact CE1-O 3.34Å
473F98.4Very high93.6Very high42 Ų4247.4 Ų47.418%0.18426%0.261CS..PPolyproline II helixtrans-97.2125.7167.3-170.8-85.6000109.7W319 F322 F323 Q326 L468 G471 T475W319-F473 HydrophobicContact CE3-CE1 4.31Å; W319-F473 HydrophobicContact CE3-CZ 4.25Å; W319-F473 AromaticContact CZ3-CE1 3.76Å; W319-F473 HydrophobicContact CZ3-CE1 3.76Å; W319-F473 HydrophobicContact CZ3-CZ 4.15Å; F322-F473 HydrophobicContact CB-CD2 4.35Å; F322-F473 HydrophobicContact CB-CE2 3.89Å; F322-F473 HydrophobicContact CB-CZ 4.34Å; F323-F473 AromaticContact CD1-CE2 3.81Å; F323-F473 HydrophobicContact CD1-CE2 3.81Å; F323-F473 AromaticContact CD1-CZ 3.71Å; F323-F473 HydrophobicContact CD1-CZ 3.71Å; F323-F473 HydrophobicContact CE1-CE1 4.45Å; F323-F473 HydrophobicContact CE1-CE2 4.07Å; F323-F473 AromaticContact CE1-CZ 3.5Å; F323-F473 HydrophobicContact CE1-CZ 3.5Å; F323-F473 HydrophobicContact CG-CE2 4.44Å; F323-F473 HydrophobicContact CG-CZ 4.39Å; F323-F473 HydrophobicContact CZ-CZ 4.03Å; Q326-F473 HydrophobicContact CB-CD2 4.25Å; Q326-F473 HydrophobicContact CG-CD2 4.46Å; L468-F473 HydrophobicContact CD1-CB 4.39Å; G471-F473 PolarHBondContact O-N 3.36Å; F473-T475 PolarHBondContact O-N 2.91Å
474P98.2Very high93.4Very high2 Ų246.6 Ų46.61%0.01326%0.258CS..PPolyproline II helixtrans-55131.5-177.4-31.838.8000114.4W319 F322 Y472 P485 H486W319-P474 HydrophobicContact CH2-CB 4.14Å; W319-P474 WeakPolarHBondContact CH2-O 3.34Å; W319-P474 HydrophobicContact CZ3-CB 3.98Å; W319-P474 WeakPolarHBondContact CZ3-O 3.37Å; F322-P474 HydrophobicContact CD1-CG 3.51Å; F322-P474 HydrophobicContact CD2-CG 3.72Å; F322-P474 HydrophobicContact CE1-CG 3.53Å; F322-P474 HydrophobicContact CE2-CG 3.77Å; F322-P474 HydrophobicContact CG-CG 3.63Å; F322-P474 HydrophobicContact CZ-CG 3.69Å; Y472-P474 HydrophobicContact CE1-CB 4.42Å; Y472-P474 HydrophobicContact CE1-CG 4.24Å; P474-P485 HydrophobicContact CB-CB 3.62Å; P474-P485 HydrophobicContact CG-CB 4.26Å; P474-H486 WeakPolarHBondContact CB-O 3.33Å
475T97.3Very high93.3Very high81 Ų8146.8 Ų46.850%0.49726%0.259SS..PPolyproline II helixtrans-76.1161.7167.555.70000110.6F473 H486F473-T475 PolarHBondContact O-N 2.91Å; T475-H486 WeakPolarHBondContact O-CB 3.43Å; T475-H486 PolarHBondContact O-N 3Å
476I96.1Very high93.2Very high35 Ų3549.8 Ų49.818%0.17927%0.273CS..EExtended strand (participates in β ladder)trans-82.2131-179.3-57.7165.8000110.2W319 Y478 H483W319-I476 HydrophobicContact CH2-CG1 3.99Å; W319-I476 HydrophobicContact CZ2-CG1 3.97Å; I476-Y478 HydrophobicContact CB-CE1 4.11Å; I476-Y478 HydrophobicContact CB-CE2 4.21Å; I476-Y478 HydrophobicContact CD1-CE1 4.49Å; I476-Y478 WeakPolarHBondContact CD1-OH 3.24Å; I476-Y478 HydrophobicContact CG2-CD1 3.8Å; I476-Y478 HydrophobicContact CG2-CE1 3.43Å; I476-Y478 VanDerWaalsContact CG2-CE1 3.43Å; I476-Y478 HydrophobicContact CG2-CE2 4.31Å; I476-Y478 HydrophobicContact CG2-CG 4.38Å; I476-H483 HydrophobicContact CG2-CB 3.67Å
477N92.5Very high93.1Very high43 Ų4353.8 Ų53.823%0.2330%0.295CS..EExtended strand (participates in β ladder)trans-89110.4168.1-176.93.8000110.3T479 T484N477-T479 WeakPolarHBondContact OD1-CB 3.45Å; N477-T479 PolarHBondContact OD1-N 3.23Å; N477-T479 PolarHBondContact OD1-OG1 2.67Å; N477-T484 WeakPolarHBondContact CB-O 3.31Å; N477-T484 PolarHBondContact N-O 3.44Å
478Y89.3Confident93.1Very high49 Ų4952 Ų5219%0.19229%0.287CS..  trans-88.80.5178.6-64.2-59.8000114.1K76 P78 I79 I476 T480 H483K76-Y478 WeakPolarHBondContact O-CD2 3.49Å; P78-Y478 HydrophobicContact CG-CD1 3.64Å; P78-Y478 HydrophobicContact CG-CE1 3.94Å; P78-Y478 HydrophobicContact CG-CG 4.12Å; I79-Y478 HydrophobicContact CG1-CE1 4.24Å; I476-Y478 HydrophobicContact CB-CE1 4.11Å; I476-Y478 HydrophobicContact CB-CE2 4.21Å; I476-Y478 HydrophobicContact CD1-CE1 4.49Å; I476-Y478 WeakPolarHBondContact CD1-OH 3.24Å; I476-Y478 HydrophobicContact CG2-CD1 3.8Å; I476-Y478 HydrophobicContact CG2-CE1 3.43Å; I476-Y478 VanDerWaalsContact CG2-CE1 3.43Å; I476-Y478 HydrophobicContact CG2-CE2 4.31Å; I476-Y478 HydrophobicContact CG2-CG 4.38Å; Y478-T480 VanDerWaalsContact C-N 3.31Å; Y478-T480 PolarHBondContact O-N 2.85Å; Y478-H483 AromaticContact CD1-CD2 3.74Å; Y478-H483 AromaticContact CD1-CE1 3.48Å; Y478-H483 VanDerWaalsContact CD1-CE1 3.48Å; Y478-H483 WeakPolarHBondContact CD1-CE1 2.95Å; Y478-H483 AromaticContact CD1-CG 3.92Å; Y478-H483 AromaticContact CD1-ND1 3.77Å; Y478-H483 AromaticContact CD1-NE2 3.47Å; Y478-H483 WeakPolarHBondContact CD1-NE2 3.36Å; Y478-H483 AromaticContact CE1-CE1 3.6Å; Y478-H483 AromaticContact CE1-ND1 3.66Å
479T79.2Confident93.1Very high106 Ų10653.2 Ų53.265%0.6529%0.293SS*.SBendtrans-72.1-26.7-175.7-48.20000112.8H233 N477H233-T479 PolarHBondContact CE1-O 3.44Å; H233-T479 PolarHBondContact ND1-O 2.71Å; N477-T479 WeakPolarHBondContact OD1-CB 3.45Å; N477-T479 PolarHBondContact OD1-N 3.23Å; N477-T479 PolarHBondContact OD1-OG1 2.67Å
480T75.8Confident93.1Very high59 Ų5952.2 Ų52.236%0.36229%0.287SS..SBendtrans-99.6153.5-179.348.50000110.7Y478 I482Y478-T480 VanDerWaalsContact C-N 3.31Å; Y478-T480 PolarHBondContact O-N 2.85Å; T480-I482 WeakPolarHBondContact CB-O 3.49Å; T480-I482 PolarHBondContact O-N 2.83Å; T480-I482 PolarHBondContact OG1-O 3.09Å
481M76.3Confident93.2Very high74 Ų7448.6 Ų48.637%0.36526%0.262SS..SBendtrans-66-23.8179-68.9-164.8-56.600113.3L131 F231L131-M481 HydrophobicContact CD1-SD 4.38Å; F231-M481 VanDerWaalsContact C-CE 3.4Å; F231-M481 VanDerWaalsContact CA-CE 3.47Å; F231-M481 HydrophobicContact CB-CE 3.26Å; F231-M481 HydrophobicContact CD1-CE 3.9Å; F231-M481 HydrophobicContact CG-CE 3.92Å; F231-M481 VanDerWaalsContact O-CE 3.23Å; F231-M481 WeakPolarHBondContact O-CE 3.42Å
482I88.1Confident93.2Very high36 Ų3646 Ų4619%0.18523%0.234CC..SBendtrans-107.8123.9168.8-61.8174.4000106.7H311 T315 P373 T480 T484H311-I482 HydrophobicContact CB-CD1 3.27Å; T315-I482 HydrophobicContact CG2-CG2 3.75Å; P373-I482 HydrophobicContact CB-CG2 3.92Å; T480-I482 WeakPolarHBondContact CB-O 3.49Å; T480-I482 PolarHBondContact O-N 2.83Å; T480-I482 PolarHBondContact OG1-O 3.09Å; I482-T484 PolarHBondContact O-N 3.28Å
483H92.4Very high93.2Very high16 Ų1646.1 Ų46.17%0.07424%0.236CC..  trans-74.2113.3-174.1-65164.8000111.9M375 I476 Y478M375-H483 VanDerWaalsContact CB-CE1 3.4Å; M375-H483 WeakPolarHBondContact CB-CE1 3.05Å; M375-H483 VanDerWaalsContact CE-CE1 3.43Å; M375-H483 WeakPolarHBondContact CE-CE1 3.49Å; M375-H483 WeakPolarHBondContact CE-NE2 3.45Å; M375-H483 WeakPolarHBondContact CG-CE1 3.45Å; I476-H483 HydrophobicContact CG2-CB 3.67Å; Y478-H483 AromaticContact CD1-CD2 3.74Å; Y478-H483 AromaticContact CD1-CE1 3.48Å; Y478-H483 VanDerWaalsContact CD1-CE1 3.48Å; Y478-H483 WeakPolarHBondContact CD1-CE1 2.95Å; Y478-H483 AromaticContact CD1-CG 3.92Å; Y478-H483 AromaticContact CD1-ND1 3.77Å; Y478-H483 AromaticContact CD1-NE2 3.47Å; Y478-H483 WeakPolarHBondContact CD1-NE2 3.36Å; Y478-H483 AromaticContact CE1-CE1 3.6Å; Y478-H483 AromaticContact CE1-ND1 3.66Å
484T94.8Very high93.2Very high19 Ų1949.5 Ų49.512%0.11725%0.248CC..EExtended strand (participates in β ladder)trans-98157.8-178.360.20000111.8F192 T315 N477 I482F192-T484 HydrophobicContact CE1-CG2 3.78Å; F192-T484 HydrophobicContact CE2-CG2 4.29Å; F192-T484 HydrophobicContact CZ-CG2 3.54Å; T315-T484 HydrophobicContact CG2-CG2 3.87Å; N477-T484 WeakPolarHBondContact CB-O 3.31Å; N477-T484 PolarHBondContact N-O 3.44Å; I482-T484 PolarHBondContact O-N 3.28Å
485P97.1Very high93Very high5 Ų550.9 Ų50.93%0.03225%0.253CS..EExtended strand (participates in β ladder)trans-71134169.228.9-34.3000111.2F192 A318 W319 P474 P488F192-P485 HydrophobicContact CB-CG 4.09Å; F192-P485 HydrophobicContact CG-CG 4.26Å; A318-P485 HydrophobicContact CB-CG 4.14Å; W319-P485 HydrophobicContact CD2-CB 4.36Å; W319-P485 HydrophobicContact CE3-CB 4.37Å; W319-P485 HydrophobicContact CH2-CB 3.74Å; W319-P485 VanDerWaalsContact CZ2-CA 3.48Å; W319-P485 HydrophobicContact CZ2-CB 3.73Å; W319-P485 HydrophobicContact CZ3-CB 4.07Å; P474-P485 HydrophobicContact CB-CB 3.62Å; P474-P485 HydrophobicContact CG-CB 4.26Å; P485-P488 HydrophobicContact CB-CB 3.99Å; P485-P488 HydrophobicContact CG-CB 3.75Å; P485-P488 HydrophobicContact CG-CG 4.3Å
486H95.4Very high92.2Very high101 Ų10156.3 Ų56.347%0.46827%0.269SS..SBendtrans-82.7138.8173.9-174.7-83.7000110.9Y472 P474 T475Y472-H486 PolarHBondContact OH-O 3.47Å; P474-H486 WeakPolarHBondContact CB-O 3.33Å; T475-H486 WeakPolarHBondContact O-CB 3.43Å; T475-H486 PolarHBondContact O-N 3Å
487N96.6Very high90.5Very high85 Ų8564.7 Ų64.746%0.45531%0.308SS..SBendtrans44.258.4-174-171.540.9000113.8Y472 I489Y472-N487 HydrophobicContact CE1-CB 3.93Å; Y472-N487 WeakPolarHBondContact CE1-O 3.34Å; N487-I489 PolarHBondContact O-N 2.76Å
488P97.7Very high90.4Very high11 Ų1165.8 Ų65.87%0.07131%0.311CS..  trans-8052.1-172.333.8-34.9000113.1N190 L191 F192 F322 P485N190-P488 CarbonylContact C-O 3.54Å; N190-P488 WeakPolarHBondContact CA-O 3.44Å; N190-P488 WeakPolarHBondContact OD1-CG 3.29Å; L191-P488 PolarHBondContact N-O 2.85Å; F192-P488 HydrophobicContact CB-CB 3.84Å; F192-P488 HydrophobicContact CB-CG 3.59Å; F322-P488 HydrophobicContact CE2-CB 3.7Å; F322-P488 VanDerWaalsContact CZ-C 3.47Å; F322-P488 VanDerWaalsContact CZ-CA 3.49Å; F322-P488 HydrophobicContact CZ-CB 3.82Å; P485-P488 HydrophobicContact CB-CB 3.99Å; P485-P488 HydrophobicContact CG-CB 3.75Å; P485-P488 HydrophobicContact CG-CG 4.3Å
489I98.6Very high90.4Very high48 Ų4866.6 Ų66.625%0.24632%0.318CS..EExtended strand (participates in β ladder)trans-82127.5171.1-52.3-56.5000109.1E188 R189 N190 V469 N487E188-I489 HydrophobicContact CB-CG2 3.93Å; R189-I489 WeakPolarHBondContact O-CA 3.21Å; N190-I489 HydrophobicContact CB-CD1 3.83Å; V469-I489 HydrophobicContact CG2-CG2 4.12Å; N487-I489 PolarHBondContact O-N 2.76Å
490I98.7Very high91.1Very high0 Ų064.4 Ų64.40%030%0.299CS..EExtended strand (participates in β ladder)trans-119.9144.8176.1-154.4165.5000110W183 E188 R189 L191 F322 A325 F466 E467W183-I490 HydrophobicContact CH2-CG2 4.22Å; W183-I490 HydrophobicContact CZ3-CG2 4.31Å; E188-I490 WeakPolarHBondContact CA-O 3.45Å; R189-I490 PolarHBondContact N-O 3.21Å; R189-I490 VanDerWaalsContact N-O 3.11Å; R189-I490 PolarHBondContact O-N 3.38Å; L191-I490 HydrophobicContact CB-CB 4.18Å; L191-I490 HydrophobicContact CB-CG2 3.73Å; L191-I490 HydrophobicContact CD1-CG2 4.32Å; L191-I490 HydrophobicContact CD2-CB 4.48Å; L191-I490 HydrophobicContact CD2-CD1 3.66Å; L191-I490 HydrophobicContact CD2-CG2 4.23Å; L191-I490 HydrophobicContact CG-CG2 4.29Å; F322-I490 HydrophobicContact CD1-CD1 4.41Å; F322-I490 HydrophobicContact CE1-CB 4.11Å; F322-I490 HydrophobicContact CE1-CD1 4.3Å; F322-I490 HydrophobicContact CE1-CG1 4.18Å; F322-I490 HydrophobicContact CZ-CB 4.22Å; A325-I490 HydrophobicContact CB-CD1 3.92Å; A325-I490 HydrophobicContact CB-CG1 4.36Å; F466-I490 HydrophobicContact CB-CD1 3.87Å; F466-I490 HydrophobicContact CB-CG1 4.34Å; F466-I490 HydrophobicContact CD1-CD1 3.85Å; F466-I490 HydrophobicContact CD1-CG1 4.24Å; F466-I490 HydrophobicContact CD1-CG2 4.06Å; F466-I490 HydrophobicContact CE1-CG2 4.44Å; F466-I490 HydrophobicContact CG-CD1 4.17Å; E467-I490 WeakPolarHBondContact O-CG1 3.17Å
491R98.8Very high92Very high71 Ų7164.8 Ų64.827%0.26830%0.296SS..EExtended strand (participates in β ladder)trans-89.9139.1170.1-177-179.9-59.9141.31.1109.4G187 E188 F466 E467 V469 D470G187-R491 WeakPolarHBondContact O-CA 3.46Å; E188-R491 HydrophobicContact CG-CB 4.04Å; E188-R491 HydrophobicContact CG-CG 4.18Å; E188-R491 IonicContact OE1-CZ 3.8Å; E188-R491 VanDerWaalsContact OE1-CZ 3.27Å; E188-R491 IonicContact OE1-NE 3.62Å; E188-R491 PolarHBondContact OE1-NE 3.29Å; E188-R491 IonicContact OE1-NH2 3.27Å; E188-R491 PolarHBondContact OE1-NH2 3.43Å; F466-R491 CarbonylContact C-O 3.51Å; F466-R491 WeakPolarHBondContact CA-O 3.35Å; E467-R491 HydrophobicContact CB-CB 4.01Å; E467-R491 HydrophobicContact CB-CG 4.37Å; E467-R491 PolarHBondContact N-O 3.31Å; E467-R491 PolarHBondContact O-N 2.88Å; E467-R491 IonicContact OE2-NH1 3.92Å; V469-R491 HydrophobicContact CG2-CB 4.05Å; D470-R491 IonicContact OD1-NH2 2.83Å
492Y98.7Very high92.9Very high5 Ų564.2 Ų64.22%0.0229%0.291CS..EExtended strand (participates in β ladder)trans-138153.1176.866-80.7000111W183 S186 G187 R189 Y464 E465W183-Y492 HydrophobicContact CB-CE2 3.73Å; W183-Y492 HydrophobicContact CD2-CD1 4.43Å; W183-Y492 AromaticContact CD2-CE1 4Å; W183-Y492 HydrophobicContact CD2-CE1 4Å; W183-Y492 HydrophobicContact CD2-CE2 4.36Å; W183-Y492 AromaticContact CD2-CZ 3.96Å; W183-Y492 AromaticContact CE3-CD1 3.37Å; W183-Y492 HydrophobicContact CE3-CD1 3.37Å; W183-Y492 AromaticContact CE3-CD2 3.81Å; W183-Y492 HydrophobicContact CE3-CD2 3.81Å; W183-Y492 AromaticContact CE3-CE1 3.34Å; W183-Y492 HydrophobicContact CE3-CE1 3.34Å; W183-Y492 AromaticContact CE3-CE2 3.79Å; W183-Y492 HydrophobicContact CE3-CE2 3.79Å; W183-Y492 AromaticContact CE3-CG 3.61Å; W183-Y492 HydrophobicContact CE3-CG 3.61Å; W183-Y492 AromaticContact CE3-CZ 3.56Å; W183-Y492 HydrophobicContact CG-CE2 4.41Å; W183-Y492 HydrophobicContact CH2-CD1 4.46Å; W183-Y492 AromaticContact CZ3-CD1 3.39Å; W183-Y492 HydrophobicContact CZ3-CD1 3.39Å; W183-Y492 HydrophobicContact CZ3-CD2 4.46Å; W183-Y492 AromaticContact CZ3-CE1 3.71Å; W183-Y492 HydrophobicContact CZ3-CE1 3.71Å; W183-Y492 AromaticContact CZ3-CG 3.81Å; W183-Y492 HydrophobicContact CZ3-CG 3.81Å; W183-Y492 VanDerWaalsContact O-CE2 3.26Å; W183-Y492 WeakPolarHBondContact O-CE2 3.33Å; W183-Y492 VanDerWaalsContact O-CZ 3.31Å; W183-Y492 PolarHBondContact O-OH 3.45Å; S186-Y492 CarbonylContact C-O 3.59Å; S186-Y492 WeakPolarHBondContact CA-O 3.34Å; S186-Y492 WeakPolarHBondContact CB-O 3.47Å; G187-Y492 PolarHBondContact N-O 3.15Å; G187-Y492 WeakPolarHBondContact O-CD1 3.48Å; G187-Y492 WeakPolarHBondContact O-CE1 3.17Å; G187-Y492 PolarHBondContact O-N 3.4Å; R189-Y492 HydrophobicContact CB-CE1 4.19Å; R189-Y492 HydrophobicContact CG-CE1 3.73Å; Y464-Y492 AromaticContact CD1-CD2 3.64Å; Y464-Y492 HydrophobicContact CD1-CD2 3.64Å; Y464-Y492 HydrophobicContact CD1-CE2 4.44Å; Y464-Y492 AromaticContact CE1-CD2 3.69Å; Y464-Y492 HydrophobicContact CE1-CD2 3.69Å; Y464-Y492 HydrophobicContact CE1-CE2 4.04Å; Y464-Y492 HydrophobicContact CG-CD2 4.21Å; E465-Y492 WeakPolarHBondContact O-CA 3.2Å
493K98.3Very high93.2Very high80 Ų8066.1 Ų66.135%0.34830%0.298SS..EExtended strand (participates in β ladder)trans-142.9144.4170.167.4-167.2-178-150.40109.6D185 Y464 E465 E467 R495D185-K493 CarbonylContact O-C 3.43Å; D185-K493 WeakPolarHBondContact O-CA 3.44Å; Y464-K493 CarbonylContact C-O 3.55Å; Y464-K493 VanDerWaalsContact CA-O 3.28Å; Y464-K493 WeakPolarHBondContact CA-O 3.36Å; E465-K493 HydrophobicContact CB-CG 4.14Å; E465-K493 VanDerWaalsContact CD-NZ 3.28Å; E465-K493 PolarHBondContact N-O 3.07Å; E465-K493 PolarHBondContact O-N 3.02Å; E465-K493 WeakPolarHBondContact OE1-CE 3.44Å; E465-K493 IonicContact OE1-NZ 2.71Å; E465-K493 PolarHBondContact OE1-NZ 3.45Å; E465-K493 WeakPolarHBondContact OE2-CE 3.49Å; E465-K493 IonicContact OE2-NZ 2.89Å; E465-K493 PolarHBondContact OE2-NZ 3.09Å; E465-K493 VanDerWaalsContact OE2-NZ 3.1Å; E467-K493 IonicContact OE1-NZ 2.96Å; E467-K493 PolarHBondContact OE1-NZ 2.83Å; K493-R495 PolarHBondContact O-N 3.39Å
494R97.4Very high93.3Very high113 Ų11369.6 Ų69.643%0.42631%0.314SS..EExtended strand (participates in β ladder)trans-60.2130.5-179.7-174.3174-67.3-93.1-10.3109.3G184 D185 L463 Y464G184-R494 PolarHBondContact O-NH2 2.9Å; D185-R494 HydrophobicContact CB-CB 4.49Å; D185-R494 PolarHBondContact O-N 2.75Å; D185-R494 IonicContact OD1-CZ 3.44Å; D185-R494 IonicContact OD1-NE 2.77Å; D185-R494 PolarHBondContact OD1-NE 2.72Å; D185-R494 IonicContact OD1-NH2 3.13Å; D185-R494 PolarHBondContact OD1-NH2 3.47Å; L463-R494 WeakPolarHBondContact O-CA 3.46Å; Y464-R494 HydrophobicContact CD1-CB 4.47Å
495R94Very high93.2Very high32 Ų3273.5 Ų73.512%0.12133%0.33CS..PPolyproline II helixtrans-73.1133.5177.8-164.1171.6-88-92.92.5108.6D332 Y335 L461 L463 K493 Q497D332-R495 IonicContact OD1-CZ 3.57Å; D332-R495 IonicContact OD1-NH1 2.71Å; D332-R495 PolarHBondContact OD1-NH1 3.3Å; D332-R495 IonicContact OD1-NH2 2.86Å; D332-R495 PolarHBondContact OD1-NH2 3.33Å; Y335-R495 VanDerWaalsContact CD2-CD 3.43Å; Y335-R495 HydrophobicContact CE2-CG 4.46Å; Y335-R495 VanDerWaalsContact CZ-CD 3.42Å; L461-R495 WeakPolarHBondContact O-CD 3.5Å; L461-R495 PolarHBondContact O-NE 2.79Å; L463-R495 PolarHBondContact O-N 2.74Å; K493-R495 PolarHBondContact O-N 3.39Å; R495-Q497 PolarHBondContact O-N 3Å
496K80.3Confident92.9Very high194 Ų19479.3 Ų79.384%0.84335%0.354SS*.PPolyproline II helixtrans-73.4123.4173.1-66.8-177.7179.5-179.50107.6
497Q60Low92.6Very high211 Ų21177.3 Ų77.399%0.98634%0.344SS*.  trans-70.40177.9-72.1-175-19.600111.4R495R495-Q497 PolarHBondContact O-N 3Å

Retrieved 497 of 497 residues in 699.2 ms (Link to these results)