A0A087XN44_POEFO Loading...

Sodium/hydrogen exchanger

AlphaFold DB , UniProt , Accession A0A087XN44, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 659 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.9	Very low	42.3	Very low	185 Å²	185	130.6 Å²	130.6	91%	0.911	61%	0.612	S	S	*	*				0	-42.5	0	-93.4	-164.8	-174.6	0	0	112.4	D3 I4 K5	M1-D3 VanDerWaalsContact C-N 3.35Å; M1-D3 PolarHBondContact O-N 2.87Å; M1-I4 PolarHBondContact O-N 3.17Å; M1-K5 PolarHBondContact O-N 3Å
2	R	35.6	Very low	43.3	Very low	178 Å²	178	131.9 Å²	131.9	67%	0.672	61%	0.614	S	S	*	*	H	α-helix	trans	-59.1	-47.2	-178.2	-146.1	173.2	-69.1	-163.4	1.1	111.1	I4 K5 V6	R2-I4 VanDerWaalsContact C-N 3.33Å; R2-I4 PolarHBondContact O-N 3.23Å; R2-K5 WeakPolarHBondContact O-CB 3.39Å; R2-K5 PolarHBondContact O-N 3.19Å; R2-K5 VanDerWaalsContact O-N 3.11Å; R2-V6 PolarHBondContact O-N 2.92Å
3	D	38.7	Very low	43.8	Very low	103 Å²	103	127.6 Å²	127.6	55%	0.551	60%	0.598	S	S	*	*	H	α-helix	trans	-60.1	-38.1	176.2	-20.8	-86.8	0	0	0	112.8	M1 V6 K7	M1-D3 VanDerWaalsContact C-N 3.35Å; M1-D3 PolarHBondContact O-N 2.87Å; D3-V6 PolarHBondContact O-N 2.86Å; D3-K7 VanDerWaalsContact O-CB 3.31Å; D3-K7 WeakPolarHBondContact O-CB 3.45Å; D3-K7 VanDerWaalsContact O-CG 3.31Å; D3-K7 WeakPolarHBondContact O-CG 3.46Å; D3-K7 PolarHBondContact O-N 3.3Å
4	I	40.3	Very low	44.4	Very low	107 Å²	107	125.1 Å²	125.1	55%	0.549	59%	0.59	S	S	.	*	H	α-helix	trans	-66.8	-39.7	177.6	-64.8	169	0	0	0	109.8	M1 R2 L8	M1-I4 PolarHBondContact O-N 3.17Å; R2-I4 VanDerWaalsContact C-N 3.33Å; R2-I4 PolarHBondContact O-N 3.23Å; I4-L8 HydrophobicContact CG2-CD1 4.27Å; I4-L8 WeakPolarHBondContact O-CB 3.32Å; I4-L8 PolarHBondContact O-N 2.66Å
5	K	39.4	Very low	44.8	Very low	163 Å²	163	123.1 Å²	123.1	71%	0.709	58%	0.583	S	S	*	*	H	α-helix	trans	-66.7	-43.3	174.5	-71.8	-171.9	174	-173.2	0	112	M1 R2 L8 F9	M1-K5 PolarHBondContact O-N 3Å; R2-K5 WeakPolarHBondContact O-CB 3.39Å; R2-K5 PolarHBondContact O-N 3.19Å; R2-K5 VanDerWaalsContact O-N 3.11Å; K5-L8 PolarHBondContact O-N 2.98Å; K5-F9 VanDerWaalsContact O-CB 3.29Å; K5-F9 WeakPolarHBondContact O-CB 3.45Å; K5-F9 PolarHBondContact O-N 2.82Å
6	V	45.4	Very low	45.8	Very low	84 Å²	84	122.8 Å²	122.8	51%	0.509	58%	0.579	S	S	.	*	H	α-helix	trans	-63.3	-44.4	176.6	176.5	0	0	0	0	111.2	R2 D3 F9 S10	R2-V6 PolarHBondContact O-N 2.92Å; D3-V6 PolarHBondContact O-N 2.86Å; V6-F9 PolarHBondContact O-N 3.32Å; V6-S10 WeakPolarHBondContact O-CB 3.42Å; V6-S10 PolarHBondContact O-N 3.4Å
7	K	43.6	Very low	45.9	Very low	154 Å²	154	121.8 Å²	121.8	67%	0.67	57%	0.573	S	S	*	*	H	α-helix	trans	-65.4	-42.7	176	-72.6	177.3	178.7	-178.9	0	112.1	D3 F9 S10 W11	D3-K7 VanDerWaalsContact O-CB 3.31Å; D3-K7 WeakPolarHBondContact O-CB 3.45Å; D3-K7 VanDerWaalsContact O-CG 3.31Å; D3-K7 WeakPolarHBondContact O-CG 3.46Å; D3-K7 PolarHBondContact O-N 3.3Å; K7-F9 VanDerWaalsContact C-N 3.34Å; K7-F9 PolarHBondContact O-N 2.79Å; K7-S10 PolarHBondContact O-N 3.17Å; K7-W11 WeakPolarHBondContact O-CB 3.39Å; K7-W11 PolarHBondContact O-N 3.27Å
8	L	42.4	Very low	46.4	Very low	122 Å²	122	119.1 Å²	119.1	64%	0.639	57%	0.565	S	S	*	*	H	α-helix	trans	-60.3	-42.4	172.6	-113.2	71.5	0	0	0	112.1	I4 K5 W11 F12	I4-L8 HydrophobicContact CG2-CD1 4.27Å; I4-L8 WeakPolarHBondContact O-CB 3.32Å; I4-L8 PolarHBondContact O-N 2.66Å; K5-L8 PolarHBondContact O-N 2.98Å; L8-W11 CarbonylContact O-C 3.49Å; L8-W11 PolarHBondContact O-N 3.3Å; L8-F12 VanDerWaalsContact O-CB 3.31Å; L8-F12 WeakPolarHBondContact O-CB 3.48Å; L8-F12 PolarHBondContact O-N 3.26Å
9	F	48.8	Very low	46.7	Very low	113 Å²	113	120.8 Å²	120.8	50%	0.496	57%	0.57	S	S	.	*	H	α-helix	trans	-69.8	-41.3	-178.3	-172.9	-93.5	0	0	0	111.9	K5 V6 K7 F12 L13 F178	K5-F9 VanDerWaalsContact O-CB 3.29Å; K5-F9 WeakPolarHBondContact O-CB 3.45Å; K5-F9 PolarHBondContact O-N 2.82Å; V6-F9 PolarHBondContact O-N 3.32Å; K7-F9 VanDerWaalsContact C-N 3.34Å; K7-F9 PolarHBondContact O-N 2.79Å; F9-F12 PolarHBondContact O-N 2.71Å; F9-L13 PolarHBondContact O-N 3.1Å; F9-F178 AromaticContact CE1-CZ 3.93Å; F9-F178 HydrophobicContact CE1-CZ 3.93Å; F9-F178 HydrophobicContact CZ-CZ 4.18Å
10	S	46.1	Very low	46.8	Very low	51 Å²	51	119.5 Å²	119.5	36%	0.357	57%	0.567	S	S	.	*	H	α-helix	trans	-60	-45.4	170.7	178.9	0	0	0	0	111.5	V6 K7 F12 L13 L14	V6-S10 WeakPolarHBondContact O-CB 3.42Å; V6-S10 PolarHBondContact O-N 3.4Å; K7-S10 PolarHBondContact O-N 3.17Å; S10-F12 VanDerWaalsContact C-N 3.33Å; S10-F12 PolarHBondContact O-N 3.26Å; S10-L13 PolarHBondContact O-N 2.88Å; S10-L14 VanDerWaalsContact O-CB 3.32Å; S10-L14 WeakPolarHBondContact O-CB 3.17Å; S10-L14 PolarHBondContact O-N 2.83Å
11	W	51.6	Low	46.8	Very low	177 Å²	177	117.5 Å²	117.5	67%	0.67	56%	0.564	S	S	*	*	H	α-helix	trans	-61.7	-38.2	172.3	-115.2	44.9	0	0	0	112.8	K7 L8 L14 L15	K7-W11 WeakPolarHBondContact O-CB 3.39Å; K7-W11 PolarHBondContact O-N 3.27Å; L8-W11 CarbonylContact O-C 3.49Å; L8-W11 PolarHBondContact O-N 3.3Å; W11-L14 PolarHBondContact O-N 2.98Å; W11-L15 HydrophobicContact CE3-CD1 4.02Å; W11-L15 WeakPolarHBondContact O-CB 3.38Å; W11-L15 WeakPolarHBondContact O-CD1 3.39Å; W11-L15 WeakPolarHBondContact O-CG 3.31Å; W11-L15 PolarHBondContact O-N 3.5Å
12	F	55.4	Low	47.4	Very low	146 Å²	146	111.9 Å²	111.9	64%	0.64	54%	0.541	S	S	*	.	H	α-helix	trans	-68.7	-39.9	178.9	-166.5	-91.4	0	0	0	111.6	L8 F9 S10 F16	L8-F12 VanDerWaalsContact O-CB 3.31Å; L8-F12 WeakPolarHBondContact O-CB 3.48Å; L8-F12 PolarHBondContact O-N 3.26Å; F9-F12 PolarHBondContact O-N 2.71Å; S10-F12 VanDerWaalsContact C-N 3.33Å; S10-F12 PolarHBondContact O-N 3.26Å; F12-F16 VanDerWaalsContact O-CB 3.27Å; F12-F16 WeakPolarHBondContact O-CB 3.41Å; F12-F16 PolarHBondContact O-N 3.41Å
13	L	49.6	Very low	47.8	Very low	76 Å²	76	106.4 Å²	106.4	40%	0.398	53%	0.53	S	S	.	.	H	α-helix	trans	-65.9	-45.6	174.2	-159.7	77	0	0	0	111	F9 S10 F16 F17	F9-L13 PolarHBondContact O-N 3.1Å; S10-L13 PolarHBondContact O-N 2.88Å; L13-F16 WeakPolarHBondContact O-CB 3.26Å; L13-F16 PolarHBondContact O-N 3.37Å; L13-F17 HydrophobicContact CD1-CE2 4.42Å; L13-F17 HydrophobicContact CG-CD2 4.28Å; L13-F17 HydrophobicContact CG-CE2 4.24Å; L13-F17 WeakPolarHBondContact O-CD2 3.36Å; L13-F17 PolarHBondContact O-N 2.8Å
14	L	51.8	Low	48.1	Very low	93 Å²	93	105.6 Å²	105.6	49%	0.487	53%	0.525	S	S	.	.	H	α-helix	trans	-59.3	-47.8	174.8	-172.6	73.3	0	0	0	111.2	S10 W11 F16 F17 V18	S10-L14 VanDerWaalsContact O-CB 3.32Å; S10-L14 WeakPolarHBondContact O-CB 3.17Å; S10-L14 PolarHBondContact O-N 2.83Å; W11-L14 PolarHBondContact O-N 2.98Å; L14-F16 VanDerWaalsContact C-N 3.31Å; L14-F16 PolarHBondContact O-N 3.41Å; L14-F17 PolarHBondContact O-N 3.19Å; L14-V18 HydrophobicContact CG-CG2 4.46Å; L14-V18 WeakPolarHBondContact O-CB 3.11Å; L14-V18 VanDerWaalsContact O-CG2 3.24Å; L14-V18 WeakPolarHBondContact O-CG2 3.4Å; L14-V18 PolarHBondContact O-N 2.74Å
15	L	50.9	Low	48.4	Very low	94 Å²	94	106.5 Å²	106.5	49%	0.492	53%	0.53	S	S	.	.	H	α-helix	trans	-64.4	-33.5	176.5	-76	166.4	0	0	0	112.2	W11 K19	W11-L15 HydrophobicContact CE3-CD1 4.02Å; W11-L15 WeakPolarHBondContact O-CB 3.38Å; W11-L15 WeakPolarHBondContact O-CD1 3.39Å; W11-L15 WeakPolarHBondContact O-CG 3.31Å; W11-L15 PolarHBondContact O-N 3.5Å; L15-K19 WeakPolarHBondContact O-CB 3.5Å; L15-K19 PolarHBondContact O-N 2.82Å
16	F	59.8	Low	48.4	Very low	118 Å²	118	105.3 Å²	105.3	52%	0.518	53%	0.53	S	S	.	.	H	α-helix	trans	-66.1	-48.2	175.4	-175.9	-100.4	0	0	0	111.5	F12 L13 L14 K19 L20	F12-F16 VanDerWaalsContact O-CB 3.27Å; F12-F16 WeakPolarHBondContact O-CB 3.41Å; F12-F16 PolarHBondContact O-N 3.41Å; L13-F16 WeakPolarHBondContact O-CB 3.26Å; L13-F16 PolarHBondContact O-N 3.37Å; L14-F16 VanDerWaalsContact C-N 3.31Å; L14-F16 PolarHBondContact O-N 3.41Å; F16-K19 PolarHBondContact O-N 3.13Å; F16-L20 HydrophobicContact CD1-CD1 3.92Å; F16-L20 HydrophobicContact CE1-CD1 3.62Å; F16-L20 HydrophobicContact CZ-CD1 4.18Å; F16-L20 PolarHBondContact O-N 3.06Å
17	F	47.5	Very low	48.2	Very low	107 Å²	107	109.2 Å²	109.2	47%	0.469	54%	0.543	S	S	.	.	H	α-helix	trans	-67.9	-40.1	175.7	-82.7	-77.5	0	0	0	113.1	L13 L14 K19 L20 C21	L13-F17 HydrophobicContact CD1-CE2 4.42Å; L13-F17 HydrophobicContact CG-CD2 4.28Å; L13-F17 HydrophobicContact CG-CE2 4.24Å; L13-F17 WeakPolarHBondContact O-CD2 3.36Å; L13-F17 PolarHBondContact O-N 2.8Å; L14-F17 PolarHBondContact O-N 3.19Å; F17-K19 VanDerWaalsContact C-N 3.33Å; F17-K19 PolarHBondContact O-N 3.39Å; F17-L20 WeakPolarHBondContact O-CB 3.33Å; F17-L20 PolarHBondContact O-N 3.43Å; F17-C21 PolarHBondContact O-N 3.49Å
18	V	55.9	Low	47.7	Very low	73 Å²	73	109.8 Å²	109.8	44%	0.442	55%	0.546	S	S	.	.	H	α-helix	trans	-63.3	-40.3	173.5	168.6	0	0	0	0	110.9	L14 C21 V22	L14-V18 HydrophobicContact CG-CG2 4.46Å; L14-V18 WeakPolarHBondContact O-CB 3.11Å; L14-V18 VanDerWaalsContact O-CG2 3.24Å; L14-V18 WeakPolarHBondContact O-CG2 3.4Å; L14-V18 PolarHBondContact O-N 2.74Å; V18-C21 PolarHBondContact O-N 2.98Å; V18-V22 HydrophobicContact CG1-CG2 4.18Å; V18-V22 WeakPolarHBondContact O-CB 3.45Å; V18-V22 VanDerWaalsContact O-CG2 3.3Å; V18-V22 WeakPolarHBondContact O-CG2 3.34Å; V18-V22 PolarHBondContact O-N 2.74Å
19	K	50.6	Low	47.3	Very low	151 Å²	151	109.1 Å²	109.1	66%	0.657	55%	0.549	S	S	*	.	H	α-helix	trans	-68.7	-35.2	178.1	-169.3	173.5	-174.5	-179.3	0	112.3	L15 F16 F17 V22 S23	L15-K19 WeakPolarHBondContact O-CB 3.5Å; L15-K19 PolarHBondContact O-N 2.82Å; F16-K19 PolarHBondContact O-N 3.13Å; F17-K19 VanDerWaalsContact C-N 3.33Å; F17-K19 PolarHBondContact O-N 3.39Å; K19-V22 PolarHBondContact O-N 2.95Å; K19-S23 WeakPolarHBondContact O-CB 3.49Å; K19-S23 PolarHBondContact O-N 3.35Å; K19-S23 PolarHBondContact O-OG 2.83Å
20	L	49.3	Very low	46.5	Very low	95 Å²	95	111.4 Å²	111.4	50%	0.497	57%	0.566	S	S	.	*	H	α-helix	trans	-58.2	-49.6	167.7	-82.3	160.7	0	0	0	111.1	F16 F17 V22 D24	F16-L20 HydrophobicContact CD1-CD1 3.92Å; F16-L20 HydrophobicContact CE1-CD1 3.62Å; F16-L20 HydrophobicContact CZ-CD1 4.18Å; F16-L20 PolarHBondContact O-N 3.06Å; F17-L20 WeakPolarHBondContact O-CB 3.33Å; F17-L20 PolarHBondContact O-N 3.43Å; L20-V22 PolarHBondContact O-N 3.15Å; L20-D24 PolarHBondContact O-N 3.32Å
21	C	46.8	Very low	45.7	Very low	77 Å²	77	114 Å²	114	52%	0.52	58%	0.584	S	S	.	*	H	α-helix	trans	-62.8	-36.4	176.3	-72	0	0	0	0	113.8	F17 V18 I25	F17-C21 PolarHBondContact O-N 3.49Å; V18-C21 PolarHBondContact O-N 2.98Å; C21-I25 WeakPolarHBondContact O-CG1 3.15Å; C21-I25 PolarHBondContact O-N 3.44Å
22	V	45.5	Very low	44.7	Very low	68 Å²	68	111.2 Å²	111.2	41%	0.412	59%	0.587	S	S	.	*	H	α-helix	trans	-78.6	-34.5	-177.5	169.8	0	0	0	0	112.4	V18 K19 L20 D24 I25 L26	V18-V22 HydrophobicContact CG1-CG2 4.18Å; V18-V22 WeakPolarHBondContact O-CB 3.45Å; V18-V22 VanDerWaalsContact O-CG2 3.3Å; V18-V22 WeakPolarHBondContact O-CG2 3.34Å; V18-V22 PolarHBondContact O-N 2.74Å; K19-V22 PolarHBondContact O-N 2.95Å; L20-V22 PolarHBondContact O-N 3.15Å; V22-D24 VanDerWaalsContact C-N 3.29Å; V22-D24 PolarHBondContact O-N 2.89Å; V22-I25 PolarHBondContact O-N 3.39Å; V22-L26 HydrophobicContact CG1-CD1 4.14Å; V22-L26 PolarHBondContact O-N 2.76Å
23	S	44.8	Very low	43.3	Very low	63 Å²	63	108.3 Å²	108.3	44%	0.441	59%	0.589	S	S	.	*	H	α-helix	trans	-59.5	-42.4	170.2	-78.8	0	0	0	0	111.4	K19 I25 L26 E27	K19-S23 WeakPolarHBondContact O-CB 3.49Å; K19-S23 PolarHBondContact O-N 3.35Å; K19-S23 PolarHBondContact O-OG 2.83Å; S23-I25 PolarHBondContact O-N 3Å; S23-L26 PolarHBondContact O-N 2.89Å; S23-E27 PolarHBondContact O-N 3.49Å; S23-E27 VanDerWaalsContact O-N 3.14Å
24	D	44.3	Very low	42.2	Very low	85 Å²	85	112.1 Å²	112.1	46%	0.455	61%	0.609	S	S	.	*	H	α-helix	trans	-63.1	-21.4	177.5	-130.2	58.3	0	0	0	113.8	L20 V22 K156	L20-D24 PolarHBondContact O-N 3.32Å; V22-D24 VanDerWaalsContact C-N 3.29Å; V22-D24 PolarHBondContact O-N 2.89Å; D24-K156 IonicContact OD2-NZ 2.81Å; D24-K156 PolarHBondContact OD2-NZ 3.18Å
25	I	46.5	Very low	40.9	Very low	126 Å²	126	118.7 Å²	118.7	65%	0.646	63%	0.629	S	S	*	*	H	α-helix	trans	-85	-31.6	174.9	-68.4	166.8	0	0	0	111.2	C21 V22 S23	C21-I25 WeakPolarHBondContact O-CG1 3.15Å; C21-I25 PolarHBondContact O-N 3.44Å; V22-I25 PolarHBondContact O-N 3.39Å; S23-I25 PolarHBondContact O-N 3Å
26	L	40.1	Very low	39.7	Very low	138 Å²	138	122.8 Å²	122.8	72%	0.723	64%	0.643	S	S	*	*	H	α-helix	trans	-84.2	-21.7	-177.4	-76.4	163.7	0	0	0	114	V22 S23 K28	V22-L26 HydrophobicContact CG1-CD1 4.14Å; V22-L26 PolarHBondContact O-N 2.76Å; S23-L26 PolarHBondContact O-N 2.89Å; L26-K28 VanDerWaalsContact C-N 3.3Å; L26-K28 PolarHBondContact O-N 3.23Å
27	E	41.2	Very low	38.1	Very low	166 Å²	166	127.4 Å²	127.4	78%	0.776	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.9	12	177.8	-69.8	-162.4	147	0	0	114.8	S23 P29	S23-E27 PolarHBondContact O-N 3.49Å; S23-E27 VanDerWaalsContact O-N 3.14Å; E27-P29 WeakPolarHBondContact O-CD 3.44Å
28	K	33.1	Very low	37.2	Very low	166 Å²	166	128.7 Å²	128.7	72%	0.722	67%	0.669	S	S	*	*			trans	-89.4	104.2	166.5	-82.7	-170.8	174.4	-177.7	0	111.5	L26 N30	L26-K28 VanDerWaalsContact C-N 3.3Å; L26-K28 PolarHBondContact O-N 3.23Å; K28-N30 PolarHBondContact O-N 2.89Å
29	P	32.9	Very low	36.1	Very low	109 Å²	109	130.9 Å²	130.9	71%	0.708	68%	0.678	S	S	*	*			trans	-65.3	129	162.6	28.1	-33.5	0	0	0	109.6	E27 S31	E27-P29 WeakPolarHBondContact O-CD 3.44Å; P29-S31 VanDerWaalsContact C-N 3.3Å; P29-S31 PolarHBondContact O-N 2.81Å
30	N	32.8	Very low	35	Very low	160 Å²	160	131.5 Å²	131.5	86%	0.856	69%	0.689	S	S	*	*			trans	-72.3	78.9	178.3	-84.3	-23.6	0	0	0	111.8	K28 V32	K28-N30 PolarHBondContact O-N 2.89Å; N30-V32 PolarHBondContact O-N 3.14Å
31	S	30.2	Very low	34	Very low	105 Å²	105	130.4 Å²	130.4	73%	0.734	70%	0.7	S	S	*	*			trans	-87.5	79.6	169	45.3	0	0	0	0	111.1	P29 A33	P29-S31 VanDerWaalsContact C-N 3.3Å; P29-S31 PolarHBondContact O-N 2.81Å; S31-A33 PolarHBondContact O-N 3.43Å
32	V	29.6	Very low	33	Very low	120 Å²	120	136.4 Å²	136.4	73%	0.727	72%	0.72	S	S	*	*			trans	-67.8	94	172.3	-179.3	0	0	0	0	109.4	N30 L34	N30-V32 PolarHBondContact O-N 3.14Å; V32-L34 PolarHBondContact O-N 2.91Å
33	A	26.5	Very low	32.1	Very low	84 Å²	84	141.5 Å²	141.5	69%	0.694	74%	0.74	S	S	*	*			trans	-74.9	85.4	178.7	0	0	0	0	0	111.1	S31 Y35	S31-A33 PolarHBondContact O-N 3.43Å; A33-Y35 PolarHBondContact O-N 2.96Å
34	L	26	Very low	31.2	Very low	157 Å²	157	146 Å²	146	82%	0.822	76%	0.759	S	S	*	*			trans	-61.7	102	170.9	-83.6	166.4	0	0	0	110.6	V32 K36	V32-L34 PolarHBondContact O-N 2.91Å; L34-K36 VanDerWaalsContact C-N 3.28Å; L34-K36 PolarHBondContact O-N 3.23Å
35	Y	24.1	Very low	30.3	Very low	231 Å²	231	147.7 Å²	147.7	91%	0.906	77%	0.772	S	S	*	*			trans	-69.9	81.9	172.1	-107.7	-87.1	0	0	0	110.7	A33 R37	A33-Y35 PolarHBondContact O-N 2.96Å; Y35-R37 PolarHBondContact O-N 3.3Å
36	K	25.3	Very low	29.3	Very low	179 Å²	179	149.4 Å²	149.4	78%	0.778	78%	0.782	S	S	*	*			trans	-81.9	97.3	173.6	-162.3	170.9	-172	175.5	0	109.8	L34 N38	L34-K36 VanDerWaalsContact C-N 3.28Å; L34-K36 PolarHBondContact O-N 3.23Å; K36-N38 PolarHBondContact O-N 3.38Å
37	R	27.2	Very low	28.5	Very low	216 Å²	216	150.8 Å²	150.8	82%	0.815	78%	0.784	S	S	*	*			trans	-67	107.7	173.8	-179.8	179.9	-179.6	160.7	0.9	109.8	Y35	Y35-R37 PolarHBondContact O-N 3.3Å
38	N	28.5	Very low	27.8	Very low	134 Å²	134	152 Å²	152	72%	0.717	79%	0.786	S	S	*	*			trans	-112.9	141.6	161.8	-85.4	19.1	0	0	0	108.4	K36	K36-N38 PolarHBondContact O-N 3.38Å
39	D	33.3	Very low	27.3	Very low	118 Å²	118	149.6 Å²	149.6	63%	0.631	78%	0.782	S	S	*	*			trans	-82.7	169.9	171.8	-59.1	-62.8	0	0	0	111.6
40	N	26.8	Very low	26.9	Very low	165 Å²	165	152 Å²	152	88%	0.882	79%	0.789	S	S	*	*			trans	81.7	112.3	175.2	-47.1	-46.9	0	0	0	117.9
41	G	27.6	Very low	26.4	Very low	71 Å²	71	150.5 Å²	150.5	73%	0.732	79%	0.785	S	S	*	*				91.7	107.3	111.8	0	0	0	0	0	119.9
42	E	26.6	Very low	27.3	Very low	203 Å²	203	150.8 Å²	150.8	95%	0.949	79%	0.785	S	S	*	*			trans	71.4	165.4	148.4	-56.4	-167.9	144.1	0	0	119.7
43	E	27.6	Very low	27	Very low	175 Å²	175	152.7 Å²	152.7	82%	0.818	79%	0.79	S	S	*	*			trans	-91.4	156.2	-168.6	-52	172.8	117	0	0	111.9
44	N	25.2	Very low	27	Very low	158 Å²	158	156 Å²	156	85%	0.845	79%	0.791	S	S	*	*				-173.3	172.3	115.7	-108.3	-77.7	0	0	0	115.4
45	V	25.9	Very low	27	Very low	121 Å²	121	153.5 Å²	153.5	73%	0.733	78%	0.779	S	S	*	*			trans	-108.6	141.7	-173.1	169.6	0	0	0	0	111.2
46	L	23.9	Very low	27	Very low	162 Å²	162	150.1 Å²	150.1	85%	0.848	77%	0.769	S	S	*	*				-174.8	153.6	127.8	-149.3	55.7	0	0	0	115.2
47	H	24.9	Very low	27	Very low	166 Å²	166	148.5 Å²	148.5	77%	0.769	76%	0.764	S	S	*	*			trans	-69.9	159.3	162.1	-71.3	-99.4	0	0	0	112.8
48	K	24.8	Very low	27	Very low	191 Å²	191	144.7 Å²	144.7	83%	0.83	76%	0.758	S	S	*	*				-177.1	165.8	96.6	-140	167	-179.3	-177.8	0	115
49	D	24.5	Very low	26.9	Very low	117 Å²	117	146 Å²	146	63%	0.626	76%	0.764	S	S	*	*			trans	-75.3	158.5	-177.9	-33.8	-97	0	0	0	114.5
50	N	24.3	Very low	26.6	Very low	159 Å²	159	149.2 Å²	149.2	85%	0.85	78%	0.775	S	S	*	*				178	153.4	111.3	-90.7	-41.2	0	0	0	114.9
51	T	22	Very low	26.5	Very low	128 Å²	128	144.1 Å²	144.1	79%	0.785	76%	0.762	S	S	*	*			trans	-113.8	-170.5	169.7	41.4	0	0	0	0	109.6
52	P	47.8	Very low	26.4	Very low	112 Å²	112	149 Å²	149	73%	0.727	77%	0.765	S	S	*	*			cis	-125.2	-171.1	-42.3	33.6	-16.1	0	0	0	111.8
53	L	24.8	Very low	26.5	Very low	160 Å²	160	146.3 Å²	146.3	84%	0.838	75%	0.751	S	S	*	*			trans	177.8	177.4	149.7	-97.1	156.8	0	0	0	110.5
54	Q	24.9	Very low	26.6	Very low	152 Å²	152	144.8 Å²	144.8	71%	0.71	74%	0.744	S	S	*	*				-158.5	152.8	-87.5	-174.6	175	3.4	0	0	112.8
55	D	25.9	Very low	26.6	Very low	105 Å²	105	142.9 Å²	142.9	56%	0.561	74%	0.738	S	S	*	*			trans	72.2	135.1	154.5	-92.7	27.5	0	0	0	125.6
56	K	26	Very low	26.7	Very low	160 Å²	160	145.1 Å²	145.1	70%	0.696	74%	0.74	S	S	*	*			trans	71	155.4	138.3	-72.9	-173.5	177.6	100.2	0	121.9
57	Q	25.3	Very low	26.9	Very low	146 Å²	146	144.7 Å²	144.7	68%	0.682	73%	0.734	S	S	*	*			cis	-170.1	155.4	-27.3	-119.2	-179.1	-34.7	0	0	112.6
58	I	27.1	Very low	27.1	Very low	136 Å²	136	143.3 Å²	143.3	70%	0.697	73%	0.732	S	S	*	*			trans	73.3	108	146.6	-63.8	165.2	0	0	0	122.8
59	L	25.9	Very low	27.2	Very low	160 Å²	160	142.6 Å²	142.6	84%	0.838	73%	0.729	S	S	*	*				44.4	135.6	122.3	-155.2	78.2	0	0	0	125.1
60	H	26.8	Very low	27.3	Very low	187 Å²	187	144.9 Å²	144.9	87%	0.866	74%	0.74	S	S	*	*			trans	-153.8	160.3	139.4	-135.5	-89.1	0	0	0	113.6
61	G	24.3	Very low	27.4	Very low	58 Å²	58	140.6 Å²	140.6	60%	0.598	73%	0.734	S	S	*	*			trans	-128.1	-172.8	174.1	0	0	0	0	0	112.7
62	Q	26.9	Very low	27.5	Very low	173 Å²	173	139.7 Å²	139.7	81%	0.808	73%	0.733	S	S	*	*			cis	-130.8	-141.3	11.3	-59.5	175.2	-9.5	0	0	110.5
63	K	28.7	Very low	26.5	Very low	146 Å²	146	140.2 Å²	140.2	64%	0.635	73%	0.734	S	S	*	*			cis	-171.7	164.2	2.3	-131	169.3	-175.2	-74	0	106.3
64	E	28.9	Very low	26.6	Very low	144 Å²	144	139.8 Å²	139.8	67%	0.673	73%	0.733	S	S	*	*			cis	-139.2	-130.5	-7.9	-159.1	121.1	-111.2	0	0	108.3
65	T	25.8	Very low	26.8	Very low	118 Å²	118	137.1 Å²	137.1	72%	0.724	73%	0.73	S	S	*	*			cis	-157.4	171.9	-1.5	-19	0	0	0	0	113.4
66	Q	27.8	Very low	26.8	Very low	168 Å²	168	141 Å²	141	79%	0.785	75%	0.745	S	S	*	*			trans	-34.2	164.4	167.9	-75.6	172.4	6.8	0	0	122.2
67	Q	28.3	Very low	27	Very low	153 Å²	153	137.8 Å²	137.8	72%	0.715	74%	0.743	S	S	*	*			cis	-175.9	155	-24.2	-144.6	172.6	6.1	0	0	112.8
68	N	27.4	Very low	27.2	Very low	136 Å²	136	137.9 Å²	137.9	73%	0.727	75%	0.748	S	S	*	*			trans	20.1	166.1	152.1	-71.6	-23.3	0	0	0	125.2
69	K	26.9	Very low	27.3	Very low	177 Å²	177	134.3 Å²	134.3	77%	0.77	75%	0.745	S	S	*	*			cis	174.7	147.2	-29.9	-166.3	179.9	-178.7	178.7	0	111.5
70	L	28.3	Very low	27.4	Very low	165 Å²	165	135.7 Å²	135.7	86%	0.864	74%	0.744	S	S	*	*			trans	92.3	134.4	149.3	-146.5	75.6	0	0	0	124
71	G	25.1	Very low	27.5	Very low	69 Å²	69	132.9 Å²	132.9	71%	0.711	74%	0.735	S	S	*	*			trans	93.1	159.2	150.9	0	0	0	0	0	119.8
72	S	25.5	Very low	27.6	Very low	109 Å²	109	138.2 Å²	138.2	76%	0.762	74%	0.742	S	S	*	*			cis	-175.8	151.4	-32	45.6	0	0	0	0	114.1
73	T	25.6	Very low	27.5	Very low	122 Å²	122	138.9 Å²	138.9	75%	0.748	74%	0.737	S	S	*	*			trans	71.5	129.4	155.3	34.6	0	0	0	0	125.5
74	N	27.4	Very low	27.5	Very low	152 Å²	152	138.7 Å²	138.7	81%	0.813	74%	0.738	S	S	*	*			trans	62.4	156	138.5	-74.4	10.2	0	0	0	122.5
75	S	28.1	Very low	27.4	Very low	95 Å²	95	137 Å²	137	66%	0.664	74%	0.743	S	S	*	*			cis	-168.6	-179.8	-2.1	42.1	0	0	0	0	113.4
76	Q	27.6	Very low	27.4	Very low	186 Å²	186	138.8 Å²	138.8	87%	0.869	75%	0.748	S	S	*	*			trans	81.7	145.4	163.3	-76.1	-179.9	-30.5	0	0	119.7
77	S	29.5	Very low	27.3	Very low	93 Å²	93	140 Å²	140	65%	0.65	75%	0.753	S	S	*	*			cis	-156.7	155.7	-15.6	-151.7	0	0	0	0	114.2
78	D	28.7	Very low	27.2	Very low	148 Å²	148	138.7 Å²	138.7	79%	0.791	76%	0.756	S	S	*	*			trans	65.8	157.5	161.6	-77.7	80.6	0	0	0	120.9
79	G	29	Very low	27.1	Very low	61 Å²	61	137.5 Å²	137.5	63%	0.629	75%	0.754	S	S	*	*			cis	165	156.9	-11.3	0	0	0	0	0	116.7
80	K	29.1	Very low	27.1	Very low	189 Å²	189	136.8 Å²	136.8	82%	0.822	75%	0.753	S	S	*	*			trans	68.7	143.9	166.8	-70	-174.4	-179.5	174.3	0	120.5
81	L	27.7	Very low	27	Very low	128 Å²	128	134.6 Å²	134.6	67%	0.67	74%	0.743	S	S	*	*			cis	-170.1	154	-23.8	-151.3	58.4	0	0	0	113.1
82	F	26.5	Very low	27	Very low	170 Å²	170	141.4 Å²	141.4	75%	0.746	75%	0.748	S	S	*	*			trans	62.8	152.6	167.5	-68.1	-79.8	0	0	0	119.9
83	R	26.2	Very low	27	Very low	188 Å²	188	140.6 Å²	140.6	71%	0.709	74%	0.743	S	S	*	*			cis	-172.9	162.5	-32.1	177.3	164.6	-172.6	170.3	9.3	111.5
84	E	28.1	Very low	27	Very low	141 Å²	141	142.1 Å²	142.1	66%	0.659	75%	0.746	S	S	*	*			trans	-23.4	163.5	165.6	-53.2	165.5	128.6	0	0	118.4
85	S	26.5	Very low	27	Very low	110 Å²	110	143.2 Å²	143.2	77%	0.769	75%	0.746	S	S	*	*			cis	-156.2	172.1	30.4	-42.7	0	0	0	0	114.7
86	N	26.4	Very low	26.8	Very low	155 Å²	155	144.6 Å²	144.6	83%	0.829	75%	0.751	S	S	*	*			trans	-79.9	161.3	168.3	-56.4	-33.8	0	0	0	112.9
87	E	25.7	Very low	26.8	Very low	193 Å²	193	144.5 Å²	144.5	90%	0.902	75%	0.75	S	S	*	*				-170.7	-176.3	115.6	-105.7	175.3	-165.2	0	0	112.5
88	T	26.1	Very low	26.5	Very low	126 Å²	126	148.6 Å²	148.6	77%	0.773	76%	0.759	S	S	*	*			trans	-127	-179.4	-152.5	53.7	0	0	0	0	116
89	T	26.1	Very low	26.3	Very low	111 Å²	111	146.9 Å²	146.9	68%	0.681	76%	0.758	S	S	*	*			trans	109.9	108.3	141.2	-23.6	0	0	0	0	119.4
90	E	26.6	Very low	26	Very low	161 Å²	161	150.4 Å²	150.4	75%	0.752	77%	0.768	S	S	*	*			trans	55.7	128.6	140	-62.8	-171.8	-164.5	0	0	127.1
91	N	25	Very low	25.7	Very low	120 Å²	120	145.9 Å²	145.9	64%	0.642	77%	0.765	S	S	*	*				44.4	125.4	126.5	-51	-35.3	0	0	0	123
92	Y	25.1	Very low	25.6	Very low	211 Å²	211	144.3 Å²	144.3	83%	0.827	77%	0.771	S	S	*	*				169.9	158.8	96.7	-110.9	-78.8	0	0	0	115.4
93	S	26.3	Very low	25.5	Very low	93 Å²	93	141.3 Å²	141.3	65%	0.65	78%	0.778	S	S	*	*			trans	61.8	126.5	150.8	54.6	0	0	0	0	123.4
94	N	25.4	Very low	25.6	Very low	153 Å²	153	137.3 Å²	137.3	82%	0.818	79%	0.785	S	S	*	*				24	149.1	122.2	-50.1	-1.7	0	0	0	119.4
95	E	26.9	Very low	25.4	Very low	176 Å²	176	140.4 Å²	140.4	82%	0.822	80%	0.796	S	S	*	*				-155.2	169.2	50.8	-77.9	-173.5	138.2	0	0	115.4
96	T	24.5	Very low	25.7	Very low	124 Å²	124	140.2 Å²	140.2	76%	0.761	79%	0.792	S	S	*	*			trans	-93.3	145.1	173.4	47.9	0	0	0	0	113.4
97	H	27.5	Very low	25.8	Very low	184 Å²	184	138.9 Å²	138.9	85%	0.852	79%	0.79	S	S	*	*			trans	-141.6	129.9	155.7	-96.2	-77.7	0	0	0	113.4
98	H	23.4	Very low	26	Very low	179 Å²	179	136 Å²	136	83%	0.829	79%	0.786	S	S	*	*			trans	-85	151	167	-74.7	-93.8	0	0	0	111.1
99	S	23.8	Very low	26.3	Very low	111 Å²	111	136 Å²	136	78%	0.776	79%	0.788	S	S	*	*				177.6	116	117.8	-78.8	0	0	0	0	115
100	T	23	Very low	26.6	Very low	135 Å²	135	135 Å²	135	83%	0.828	79%	0.791	S	S	*	*				36	118.7	126	-32.7	0	0	0	0	121.3
101	A	23.3	Very low	27	Very low	94 Å²	94	132.8 Å²	132.8	78%	0.777	79%	0.79	S	S	*	*				157.2	127.8	113.4	0	0	0	0	0	117
102	A	24.1	Very low	27.5	Very low	96 Å²	96	133.1 Å²	133.1	79%	0.793	80%	0.799	S	S	*	*			trans	53.6	93.8	140	0	0	0	0	0	123.9
103	A	25.1	Very low	27.9	Very low	107 Å²	107	129.2 Å²	129.2	88%	0.884	80%	0.797	S	S	*	*				61.1	113.3	117.9	0	0	0	0	0	123.7
104	A	28.4	Very low	28.4	Very low	104 Å²	104	130.5 Å²	130.5	86%	0.86	80%	0.803	S	S	*	*			trans	-153.7	159.1	142	0	0	0	0	0	111.8
105	K	25	Very low	28.8	Very low	205 Å²	205	132.3 Å²	132.3	89%	0.891	80%	0.804	S	S	*	*			trans	-129.5	166.1	172.2	-93.2	-174.4	177.5	179.7	0	108.1
106	P	31.4	Very low	29.3	Very low	106 Å²	106	129.8 Å²	129.8	69%	0.688	80%	0.803	S	S	*	*			cis	-134.5	168.3	7.3	42.1	-25.6	0	0	0	117
107	T	29	Very low	30.6	Very low	127 Å²	127	131.6 Å²	131.6	78%	0.779	81%	0.806	S	S	*	*			trans	36.3	109.2	146.9	57	0	0	0	0	122.6
108	T	30.5	Very low	31.4	Very low	134 Å²	134	129.4 Å²	129.4	82%	0.822	80%	0.8	S	S	*	*			trans	-143.4	141.5	133.1	-59.2	0	0	0	0	108.2
109	P	31.2	Very low	32.5	Very low	125 Å²	125	124.6 Å²	124.6	81%	0.812	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-70.6	140.2	176.6	-17.6	32.1	0	0	0	113
110	A	32.3	Very low	33.8	Very low	90 Å²	90	125 Å²	125	74%	0.744	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-88.8	152.3	172.4	0	0	0	0	0	111.6
111	P	35.9	Very low	35	Very low	114 Å²	114	126.2 Å²	126.2	74%	0.74	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-65.3	158.1	176.4	28.1	-35.5	0	0	0	112.4	T113	P111-T113 PolarHBondContact O-N 3.23Å
112	P	35.8	Very low	36.5	Very low	128 Å²	128	125.4 Å²	125.4	83%	0.831	76%	0.764	S	S	*	*	P	Polyproline II helix	trans	-64.6	127.3	-174.8	26.3	-35	0	0	0	112
113	T	33.8	Very low	38	Very low	128 Å²	128	122.6 Å²	122.6	79%	0.785	75%	0.745	S	S	*	*	P	Polyproline II helix	trans	-66.5	138.3	169.7	38	0	0	0	0	110.5	P111 K115	P111-T113 PolarHBondContact O-N 3.23Å; T113-K115 PolarHBondContact O-N 2.73Å
114	P	36.6	Very low	39.6	Very low	120 Å²	120	121.2 Å²	121.2	78%	0.779	73%	0.725	S	S	*	*	P	Polyproline II helix	trans	-62.9	135.6	170.7	27.2	-33.1	0	0	0	109.2
115	K	33.3	Very low	41	Very low	192 Å²	192	122.7 Å²	122.7	84%	0.835	71%	0.712	S	S	*	*	P	Polyproline II helix	trans	-59.6	138.7	177.3	-63.6	177.8	-178.9	178.1	0	109.3	T113 I117	T113-K115 PolarHBondContact O-N 2.73Å; K115-I117 PolarHBondContact O-N 2.75Å
116	P	38.3	Very low	42.6	Very low	123 Å²	123	115 Å²	115	80%	0.799	69%	0.687	S	S	*	*	P	Polyproline II helix	trans	-61.1	130	176.2	26	-33.6	0	0	0	109.9	L118	P116-L118 PolarHBondContact O-N 3.28Å
117	I	50	Low	44	Very low	162 Å²	162	115.5 Å²	115.5	83%	0.831	68%	0.68	S	S	*	*	P	Polyproline II helix	trans	-68.1	128.9	172.8	-59.8	171.2	0	0	0	107.2	K115	K115-I117 PolarHBondContact O-N 2.75Å
118	L	44.8	Very low	45.6	Very low	137 Å²	137	115.2 Å²	115.2	72%	0.717	67%	0.67	S	S	*	*	P	Polyproline II helix	trans	-59.5	133.7	176.3	-73.6	165.4	0	0	0	109.7	P116 V120	P116-L118 PolarHBondContact O-N 3.28Å; L118-V120 PolarHBondContact O-N 3.42Å
119	P	46.2	Very low	47.2	Very low	78 Å²	78	114.7 Å²	114.7	51%	0.506	66%	0.658	S	S	.	*	P	Polyproline II helix	trans	-66.5	130.9	-176.1	27	-33.7	0	0	0	110.3	Q121 T122	P119-Q121 PolarHBondContact O-N 2.9Å; P119-T122 HydrophobicContact CG-CG2 4.31Å; P119-T122 PolarHBondContact O-N 3.49Å; P119-T122 PolarHBondContact O-OG1 2.84Å
120	V	51.4	Low	49	Very low	121 Å²	121	115.1 Å²	115.1	73%	0.733	65%	0.649	S	S	*	*	H	α-helix	trans	-52.7	-25.1	-173	179.3	0	0	0	0	113.7	L118 T122 G123 V124	L118-V120 PolarHBondContact O-N 3.42Å; V120-T122 VanDerWaalsContact C-N 3.27Å; V120-T122 PolarHBondContact O-N 3.43Å; V120-G123 WeakPolarHBondContact O-CA 3.36Å; V120-G123 PolarHBondContact O-N 3.31Å; V120-V124 PolarHBondContact O-N 3.31Å; V120-V124 VanDerWaalsContact O-N 3.12Å
121	Q	49.3	Very low	50.6	Low	160 Å²	160	117.3 Å²	117.3	75%	0.748	64%	0.644	S	S	*	*	H	α-helix	trans	-58.7	-29	173	-73	-178.8	-24.2	0	0	114.7	P119 G123 K125	P119-Q121 PolarHBondContact O-N 2.9Å; Q121-G123 VanDerWaalsContact C-N 3.34Å; Q121-K125 PolarHBondContact O-N 2.96Å; Q121-K125 VanDerWaalsContact O-N 3.16Å
122	T	53.6	Low	52	Low	76 Å²	76	114.8 Å²	114.8	47%	0.466	63%	0.629	S	S	.	*	H	α-helix	trans	-72.1	-31.3	172.5	58.4	0	0	0	0	111.7	P119 V120 A126	P119-T122 HydrophobicContact CG-CG2 4.31Å; P119-T122 PolarHBondContact O-N 3.49Å; P119-T122 PolarHBondContact O-OG1 2.84Å; V120-T122 VanDerWaalsContact C-N 3.27Å; V120-T122 PolarHBondContact O-N 3.43Å; T122-A126 WeakPolarHBondContact O-CB 3.31Å; T122-A126 PolarHBondContact O-N 3.42Å
123	G	55.4	Low	53.4	Low	38 Å²	38	111.6 Å²	111.6	39%	0.392	61%	0.61	S	S	.	*	H	α-helix	trans	-67.3	-45.6	174.7	0	0	0	0	0	112.1	V120 Q121 A126 Q127	V120-G123 WeakPolarHBondContact O-CA 3.36Å; V120-G123 PolarHBondContact O-N 3.31Å; Q121-G123 VanDerWaalsContact C-N 3.34Å; G123-A126 PolarHBondContact O-N 2.88Å; G123-Q127 VanDerWaalsContact O-CB 3.28Å; G123-Q127 WeakPolarHBondContact O-CB 3.45Å; G123-Q127 PolarHBondContact O-N 3.15Å
124	V	59.6	Low	55.3	Low	77 Å²	77	107.3 Å²	107.3	47%	0.467	59%	0.591	S	S	.	*	H	α-helix	trans	-62.5	-46.5	177.1	-178.9	0	0	0	0	111	V120 Q127 E128	V120-V124 PolarHBondContact O-N 3.31Å; V120-V124 VanDerWaalsContact O-N 3.12Å; V124-Q127 PolarHBondContact O-N 3.08Å; V124-E128 WeakPolarHBondContact O-CG 3.48Å; V124-E128 PolarHBondContact O-N 3.38Å
125	K	57.3	Low	56.7	Low	136 Å²	136	106.3 Å²	106.3	59%	0.591	58%	0.578	S	S	*	*	H	α-helix	trans	-63.8	-45.6	177	-75.5	-168	171.4	-163.9	0	113.1	Q121 Q127 E128 E129	Q121-K125 PolarHBondContact O-N 2.96Å; Q121-K125 VanDerWaalsContact O-N 3.16Å; K125-Q127 PolarHBondContact O-N 3.32Å; K125-E128 PolarHBondContact O-N 3.22Å; K125-E129 WeakPolarHBondContact O-CB 3.24Å; K125-E129 WeakPolarHBondContact O-CG 3.47Å; K125-E129 PolarHBondContact O-N 3.07Å
126	A	59.4	Low	58.1	Low	43 Å²	43	98.3 Å²	98.3	36%	0.355	55%	0.547	S	S	.	.	H	α-helix	trans	-59.8	-37.3	175.8	0	0	0	0	0	111.5	T122 G123 E129 E130	T122-A126 WeakPolarHBondContact O-CB 3.31Å; T122-A126 PolarHBondContact O-N 3.42Å; G123-A126 PolarHBondContact O-N 2.88Å; A126-E129 PolarHBondContact O-N 3.41Å; A126-E130 WeakPolarHBondContact O-CB 3.33Å; A126-E130 VanDerWaalsContact O-CG 3.31Å; A126-E130 WeakPolarHBondContact O-CG 3.45Å; A126-E130 PolarHBondContact O-N 2.84Å
127	Q	59.5	Low	59.5	Low	116 Å²	116	97.3 Å²	97.3	54%	0.542	53%	0.534	S	S	.	.	H	α-helix	trans	-78.9	-24.6	179.5	-161	164.6	-1.5	0	0	113.4	G123 V124 K125 Q131	G123-Q127 VanDerWaalsContact O-CB 3.28Å; G123-Q127 WeakPolarHBondContact O-CB 3.45Å; G123-Q127 PolarHBondContact O-N 3.15Å; V124-Q127 PolarHBondContact O-N 3.08Å; K125-Q127 PolarHBondContact O-N 3.32Å; Q127-Q131 WeakPolarHBondContact O-CB 3.34Å; Q127-Q131 VanDerWaalsContact O-CG 3.25Å; Q127-Q131 WeakPolarHBondContact O-CG 3.24Å; Q127-Q131 PolarHBondContact O-N 3.17Å; Q127-Q131 VanDerWaalsContact O-N 3.09Å
128	E	63.6	Low	60.5	Low	122 Å²	122	95.6 Å²	95.6	57%	0.57	52%	0.52	S	S	*	.	H	α-helix	trans	-71.6	-39.3	165.7	-73.9	175.7	162.8	0	0	111.3	V124 K125 Q131 S132	V124-E128 WeakPolarHBondContact O-CG 3.48Å; V124-E128 PolarHBondContact O-N 3.38Å; K125-E128 PolarHBondContact O-N 3.22Å; E128-Q131 PolarHBondContact O-N 2.89Å; E128-S132 PolarHBondContact O-N 3.3Å; E128-S132 PolarHBondContact O-OG 3.32Å
129	E	64.8	Low	61.5	Low	123 Å²	123	92.4 Å²	92.4	58%	0.575	50%	0.501	S	S	*	.	H	α-helix	trans	-68.5	-35.7	174	-73.4	169.7	-170.3	0	0	112.6	K125 A126 S132 S133	K125-E129 WeakPolarHBondContact O-CB 3.24Å; K125-E129 WeakPolarHBondContact O-CG 3.47Å; K125-E129 PolarHBondContact O-N 3.07Å; A126-E129 PolarHBondContact O-N 3.41Å; E129-S132 WeakPolarHBondContact CA-OG 3.24Å; E129-S132 PolarHBondContact O-OG 2.84Å; E129-S132 VanDerWaalsContact O-OG 3.05Å; E129-S133 WeakPolarHBondContact O-CB 3.29Å; E129-S133 PolarHBondContact O-N 3.32Å; E129-S133 PolarHBondContact O-OG 3.33Å
130	E	67.4	Low	62.4	Low	134 Å²	134	91.7 Å²	91.7	63%	0.626	50%	0.498	S	S	*	.	H	α-helix	trans	-67.3	-39.7	170.3	-78.5	175.9	178.9	0	0	111.4	A126 G134	A126-E130 WeakPolarHBondContact O-CB 3.33Å; A126-E130 VanDerWaalsContact O-CG 3.31Å; A126-E130 WeakPolarHBondContact O-CG 3.45Å; A126-E130 PolarHBondContact O-N 2.84Å; E130-G134 PolarHBondContact O-N 2.92Å
131	Q	67.4	Low	63.3	Low	136 Å²	136	91.5 Å²	91.5	64%	0.636	49%	0.492	S	S	*	.	H	α-helix	trans	-71.1	-37.7	177.9	-79.2	179.9	38.7	0	0	113.1	Q127 E128 L135	Q127-Q131 WeakPolarHBondContact O-CB 3.34Å; Q127-Q131 VanDerWaalsContact O-CG 3.25Å; Q127-Q131 WeakPolarHBondContact O-CG 3.24Å; Q127-Q131 PolarHBondContact O-N 3.17Å; Q127-Q131 VanDerWaalsContact O-N 3.09Å; E128-Q131 PolarHBondContact O-N 2.89Å; Q131-L135 PolarHBondContact O-N 3.46Å
132	S	64.9	Low	64.3	Low	60 Å²	60	86.6 Å²	86.6	42%	0.42	47%	0.47	S	S	.	.	H	α-helix	trans	-66.1	-51.9	172	62.1	0	0	0	0	110.4	E128 E129 G134 L135 S136	E128-S132 PolarHBondContact O-N 3.3Å; E128-S132 PolarHBondContact O-OG 3.32Å; E129-S132 WeakPolarHBondContact CA-OG 3.24Å; E129-S132 PolarHBondContact O-OG 2.84Å; E129-S132 VanDerWaalsContact O-OG 3.05Å; S132-G134 VanDerWaalsContact C-N 3.27Å; S132-G134 PolarHBondContact O-N 3.47Å; S132-L135 WeakPolarHBondContact O-CA 3.3Å; S132-L135 VanDerWaalsContact O-CB 3.28Å; S132-L135 WeakPolarHBondContact O-CB 3.41Å; S132-L135 PolarHBondContact O-N 3.11Å; S132-S136 PolarHBondContact O-N 2.93Å; S132-S136 PolarHBondContact O-OG 3.45Å
133	S	65.8	Low	65	Low	61 Å²	61	83.9 Å²	83.9	43%	0.427	45%	0.454	S	S	.	.	H	α-helix	trans	-55.8	-39.9	177.4	-58.6	0	0	0	0	112.7	E129 L135 S136 I137	E129-S133 WeakPolarHBondContact O-CB 3.29Å; E129-S133 PolarHBondContact O-N 3.32Å; E129-S133 PolarHBondContact O-OG 3.33Å; S133-L135 VanDerWaalsContact C-N 3.31Å; S133-L135 PolarHBondContact O-N 2.91Å; S133-S136 PolarHBondContact O-N 2.85Å; S133-I137 WeakPolarHBondContact O-CB 3.32Å; S133-I137 WeakPolarHBondContact O-CD1 3.36Å; S133-I137 VanDerWaalsContact O-CG1 3.23Å; S133-I137 WeakPolarHBondContact O-CG1 3.14Å; S133-I137 PolarHBondContact O-N 3.42Å
134	G	71.9	Confident	65.6	Low	38 Å²	38	83.5 Å²	83.5	39%	0.392	44%	0.444	S	S	.	.	H	α-helix	trans	-63.9	-33.6	174.9	0	0	0	0	0	113.3	E130 S132 F138	E130-G134 PolarHBondContact O-N 2.92Å; S132-G134 VanDerWaalsContact C-N 3.27Å; S132-G134 PolarHBondContact O-N 3.47Å; G134-F138 WeakPolarHBondContact O-CB 3.4Å; G134-F138 PolarHBondContact O-N 2.89Å
135	L	66.9	Low	66.3	Low	99 Å²	99	81 Å²	81	52%	0.518	43%	0.434	S	S	.	.	H	α-helix	trans	-71.2	-42.8	173.7	-167.7	71.4	0	0	0	111.5	Q131 S132 S133 I137 F138 F139	Q131-L135 PolarHBondContact O-N 3.46Å; S132-L135 WeakPolarHBondContact O-CA 3.3Å; S132-L135 VanDerWaalsContact O-CB 3.28Å; S132-L135 WeakPolarHBondContact O-CB 3.41Å; S132-L135 PolarHBondContact O-N 3.11Å; S133-L135 VanDerWaalsContact C-N 3.31Å; S133-L135 PolarHBondContact O-N 2.91Å; L135-I137 VanDerWaalsContact C-N 3.34Å; L135-I137 PolarHBondContact O-N 2.57Å; L135-F138 PolarHBondContact O-N 3.42Å; L135-F139 WeakPolarHBondContact O-CB 3.25Å; L135-F139 PolarHBondContact O-N 3.23Å
136	S	61.8	Low	67.1	Low	24 Å²	24	77.7 Å²	77.7	17%	0.168	42%	0.422	C	S	.	.	H	α-helix	trans	-60.4	-43.1	175.4	-27.3	0	0	0	0	111.3	S132 S133 F139 S140 E193	S132-S136 PolarHBondContact O-N 2.93Å; S132-S136 PolarHBondContact O-OG 3.45Å; S133-S136 PolarHBondContact O-N 2.85Å; S136-F139 PolarHBondContact O-N 3.28Å; S136-S140 WeakPolarHBondContact O-CB 3.1Å; S136-S140 PolarHBondContact O-N 3.46Å; S136-S140 PolarHBondContact O-OG 2.93Å; S136-E193 VanDerWaalsContact CB-CD 3.45Å; S136-E193 WeakPolarHBondContact CB-OE1 3.16Å; S136-E193 WeakPolarHBondContact CB-OE2 3.4Å; S136-E193 PolarHBondContact OG-OE1 3.01Å
137	I	69.4	Low	67.5	Low	103 Å²	103	75.9 Å²	75.9	53%	0.528	41%	0.407	S	S	.	.	H	α-helix	trans	-65	-45.2	175.8	-69.7	163.8	0	0	0	110.7	S133 L135 F139 S140 L141	S133-I137 WeakPolarHBondContact O-CB 3.32Å; S133-I137 WeakPolarHBondContact O-CD1 3.36Å; S133-I137 VanDerWaalsContact O-CG1 3.23Å; S133-I137 WeakPolarHBondContact O-CG1 3.14Å; S133-I137 PolarHBondContact O-N 3.42Å; L135-I137 VanDerWaalsContact C-N 3.34Å; L135-I137 PolarHBondContact O-N 2.57Å; I137-F139 PolarHBondContact O-N 2.71Å; I137-S140 PolarHBondContact O-N 3.32Å; I137-L141 HydrophobicContact CG2-CD1 3.96Å; I137-L141 HydrophobicContact CG2-CG 4.44Å; I137-L141 WeakPolarHBondContact O-CB 3.31Å; I137-L141 WeakPolarHBondContact O-CG 3.48Å; I137-L141 PolarHBondContact O-N 3.49Å
138	F	70.2	Confident	68.1	Low	126 Å²	126	73.7 Å²	73.7	55%	0.553	40%	0.398	S	S	*	.	H	α-helix	trans	-59.7	-44.7	176	173.6	-96	0	0	0	112	G134 L135 L141 L142	G134-F138 WeakPolarHBondContact O-CB 3.4Å; G134-F138 PolarHBondContact O-N 2.89Å; L135-F138 PolarHBondContact O-N 3.42Å; F138-L141 PolarHBondContact O-N 2.92Å; F138-L142 WeakPolarHBondContact O-CB 3.34Å; F138-L142 PolarHBondContact O-N 3.08Å
139	F	65.6	Low	68.8	Low	69 Å²	69	72.8 Å²	72.8	30%	0.303	40%	0.396	S	S	.	.	H	α-helix	trans	-65	-42.3	176.8	-172	-104.9	0	0	0	111.8	L135 S136 I137 L141 L142 V143 M175	L135-F139 WeakPolarHBondContact O-CB 3.25Å; L135-F139 PolarHBondContact O-N 3.23Å; S136-F139 PolarHBondContact O-N 3.28Å; I137-F139 PolarHBondContact O-N 2.71Å; F139-L141 PolarHBondContact O-N 2.88Å; F139-L142 WeakPolarHBondContact O-CB 3.24Å; F139-L142 PolarHBondContact O-N 3.13Å; F139-V143 HydrophobicContact CD1-CG2 4.23Å; F139-V143 HydrophobicContact CE1-CG2 3.95Å; F139-V143 HydrophobicContact CZ-CG2 4.17Å; F139-V143 VanDerWaalsContact O-CG2 3.3Å; F139-V143 WeakPolarHBondContact O-CG2 3.45Å; F139-V143 PolarHBondContact O-N 2.76Å; F139-M175 HydrophobicContact CE1-CE 4.14Å
140	S	65.8	Low	69	Low	63 Å²	63	69.3 Å²	69.3	44%	0.441	38%	0.381	S	S	.	.	H	α-helix	trans	-59.6	-44.5	175.1	-60	0	0	0	0	112.2	S136 I137 V143 V144	S136-S140 WeakPolarHBondContact O-CB 3.1Å; S136-S140 PolarHBondContact O-N 3.46Å; S136-S140 PolarHBondContact O-OG 2.93Å; I137-S140 PolarHBondContact O-N 3.32Å; S140-V143 PolarHBondContact O-N 2.64Å; S140-V144 WeakPolarHBondContact O-CG2 3.37Å; S140-V144 PolarHBondContact O-N 3.2Å
141	L	69.4	Low	69	Low	117 Å²	117	63.1 Å²	63.1	61%	0.613	35%	0.353	S	S	*	.	H	α-helix	trans	-67.1	-37.7	176.5	-70.8	171.8	0	0	0	112.3	I137 F138 F139 V144 G145	I137-L141 HydrophobicContact CG2-CD1 3.96Å; I137-L141 HydrophobicContact CG2-CG 4.44Å; I137-L141 WeakPolarHBondContact O-CB 3.31Å; I137-L141 WeakPolarHBondContact O-CG 3.48Å; I137-L141 PolarHBondContact O-N 3.49Å; F138-L141 PolarHBondContact O-N 2.92Å; F139-L141 PolarHBondContact O-N 2.88Å; L141-V144 PolarHBondContact O-N 3.38Å; L141-G145 PolarHBondContact O-N 3.28Å
142	L	70.3	Confident	69.3	Low	57 Å²	57	62.9 Å²	62.9	30%	0.298	35%	0.351	S	S	.	.	H	α-helix	trans	-61.7	-43.6	173.9	-179.9	65.6	0	0	0	111.4	F138 F139 G145 I146	F138-L142 WeakPolarHBondContact O-CB 3.34Å; F138-L142 PolarHBondContact O-N 3.08Å; F139-L142 WeakPolarHBondContact O-CB 3.24Å; F139-L142 PolarHBondContact O-N 3.13Å; L142-G145 PolarHBondContact O-N 2.99Å; L142-I146 HydrophobicContact CD1-CD1 4.4Å; L142-I146 HydrophobicContact CG-CD1 4.1Å; L142-I146 VanDerWaalsContact O-CG1 3.3Å; L142-I146 WeakPolarHBondContact O-CG1 3.47Å; L142-I146 PolarHBondContact O-N 3.38Å
143	V	67.8	Low	69.7	Low	20 Å²	20	63.2 Å²	63.2	12%	0.121	35%	0.348	C	S	.	.	H	α-helix	trans	-61.6	-47.3	176.4	166.2	0	0	0	0	111.4	F139 S140 G145 I146 C147 M175	F139-V143 HydrophobicContact CD1-CG2 4.23Å; F139-V143 HydrophobicContact CE1-CG2 3.95Å; F139-V143 HydrophobicContact CZ-CG2 4.17Å; F139-V143 VanDerWaalsContact O-CG2 3.3Å; F139-V143 WeakPolarHBondContact O-CG2 3.45Å; F139-V143 PolarHBondContact O-N 2.76Å; S140-V143 PolarHBondContact O-N 2.64Å; V143-G145 VanDerWaalsContact C-N 3.32Å; V143-G145 PolarHBondContact O-N 3.06Å; V143-I146 PolarHBondContact O-N 2.86Å; V143-C147 PolarHBondContact O-N 3.38Å; V143-C147 PolarHBondContact O-SG 3.15Å; V143-M175 HydrophobicContact CB-CE 4.26Å; V143-M175 HydrophobicContact CB-SD 4.3Å; V143-M175 HydrophobicContact CG1-CE 3.79Å; V143-M175 HydrophobicContact CG1-SD 3.51Å; V143-M175 VanDerWaalsContact CG1-SD 3.51Å; V143-M175 HydrophobicContact CG2-CE 3.43Å; V143-M175 VanDerWaalsContact CG2-CE 3.43Å; V143-M175 HydrophobicContact CG2-SD 3.78Å
144	V	68.4	Low	69.8	Low	29 Å²	29	61.4 Å²	61.4	18%	0.176	33%	0.333	C	S	.	.	H	α-helix	trans	-62.2	-40.4	176	173.5	0	0	0	0	111	S140 L141 I146 C147 I148 M433 C437	S140-V144 WeakPolarHBondContact O-CG2 3.37Å; S140-V144 PolarHBondContact O-N 3.2Å; L141-V144 PolarHBondContact O-N 3.38Å; V144-I146 PolarHBondContact O-N 3.44Å; V144-C147 WeakPolarHBondContact O-CB 3.23Å; V144-C147 PolarHBondContact O-N 3.15Å; V144-I148 HydrophobicContact CG1-CD1 3.94Å; V144-I148 WeakPolarHBondContact O-CG1 3.4Å; V144-I148 PolarHBondContact O-N 3.26Å; V144-M433 HydrophobicContact CG1-CE 4.48Å; V144-C437 VanDerWaalsContact CG2-SG 3.53Å
145	G	74.6	Confident	69.4	Low	26 Å²	26	61 Å²	61	27%	0.268	32%	0.322	S	S	.	.	H	α-helix	trans	-59.5	-43.8	173.4	0	0	0	0	0	113.1	L141 L142 V143 C147 I148 I149	L141-G145 PolarHBondContact O-N 3.28Å; L142-G145 PolarHBondContact O-N 2.99Å; V143-G145 VanDerWaalsContact C-N 3.32Å; V143-G145 PolarHBondContact O-N 3.06Å; G145-C147 VanDerWaalsContact C-N 3.34Å; G145-C147 PolarHBondContact O-N 3.32Å; G145-I148 PolarHBondContact O-N 3.25Å; G145-I149 VanDerWaalsContact O-CG1 3.28Å; G145-I149 WeakPolarHBondContact O-CG1 3.36Å; G145-I149 PolarHBondContact O-N 3.23Å
146	I	74.3	Confident	69.6	Low	66 Å²	66	61.7 Å²	61.7	34%	0.338	32%	0.321	S	S	.	.	H	α-helix	trans	-63.9	-39.1	175.3	-67.8	163.4	0	0	0	111	L142 V143 V144 I149 L150 L171	L142-I146 HydrophobicContact CD1-CD1 4.4Å; L142-I146 HydrophobicContact CG-CD1 4.1Å; L142-I146 VanDerWaalsContact O-CG1 3.3Å; L142-I146 WeakPolarHBondContact O-CG1 3.47Å; L142-I146 PolarHBondContact O-N 3.38Å; V143-I146 PolarHBondContact O-N 2.86Å; V144-I146 PolarHBondContact O-N 3.44Å; I146-I149 PolarHBondContact O-N 3.19Å; I146-L150 PolarHBondContact O-N 2.89Å; I146-L171 HydrophobicContact CG2-CD2 4.28Å
147	C	68.3	Low	70	Confident	5 Å²	5	66.8 Å²	66.8	3%	0.034	34%	0.34	C	S	.	.	H	α-helix	trans	-61.5	-45.8	174.9	-62.8	0	0	0	0	111.8	V143 V144 G145 L150 V151 L171 T436	V143-C147 PolarHBondContact O-N 3.38Å; V143-C147 PolarHBondContact O-SG 3.15Å; V144-C147 WeakPolarHBondContact O-CB 3.23Å; V144-C147 PolarHBondContact O-N 3.15Å; G145-C147 VanDerWaalsContact C-N 3.34Å; G145-C147 PolarHBondContact O-N 3.32Å; C147-L150 PolarHBondContact O-N 3.29Å; C147-V151 PolarHBondContact O-N 3.09Å; C147-L171 HydrophobicContact CB-CD2 4.21Å; C147-T436 HydrophobicContact CB-CG2 3.93Å
148	I	71	Confident	69.5	Low	69 Å²	69	68.5 Å²	68.5	35%	0.354	34%	0.344	S	S	.	.	H	α-helix	trans	-63.9	-43.5	178	-67.2	164.8	0	0	0	111	V144 G145 L150 V151 H152 M433	V144-I148 HydrophobicContact CG1-CD1 3.94Å; V144-I148 WeakPolarHBondContact O-CG1 3.4Å; V144-I148 PolarHBondContact O-N 3.26Å; G145-I148 PolarHBondContact O-N 3.25Å; I148-L150 VanDerWaalsContact C-N 3.32Å; I148-L150 PolarHBondContact O-N 3.45Å; I148-V151 PolarHBondContact O-N 3.41Å; I148-H152 PolarHBondContact O-N 3.33Å; I148-M433 HydrophobicContact CD1-CE 4.28Å
149	I	77.9	Confident	69	Low	104 Å²	104	67.1 Å²	67.1	53%	0.533	34%	0.341	S	S	.	.	H	α-helix	trans	-60.6	-41.8	175.1	-69.8	165.7	0	0	0	110.6	G145 I146 H152 L153	G145-I149 VanDerWaalsContact O-CG1 3.28Å; G145-I149 WeakPolarHBondContact O-CG1 3.36Å; G145-I149 PolarHBondContact O-N 3.23Å; I146-I149 PolarHBondContact O-N 3.19Å; I149-H152 PolarHBondContact O-N 2.82Å; I149-L153 WeakPolarHBondContact O-CB 3.33Å; I149-L153 PolarHBondContact O-N 3.3Å
150	L	70.2	Confident	68.6	Low	49 Å²	49	67 Å²	67	26%	0.257	34%	0.342	S	S	.	.	H	α-helix	trans	-64	-42.1	176.9	-177.5	66.9	0	0	0	112.4	I146 C147 I148 H152 L153 L154 L171	I146-L150 PolarHBondContact O-N 2.89Å; C147-L150 PolarHBondContact O-N 3.29Å; I148-L150 VanDerWaalsContact C-N 3.32Å; I148-L150 PolarHBondContact O-N 3.45Å; L150-H152 VanDerWaalsContact C-N 3.35Å; L150-H152 PolarHBondContact O-N 3.07Å; L150-L153 HydrophobicContact CD1-CD2 4.34Å; L150-L153 WeakPolarHBondContact O-CB 3.32Å; L150-L153 PolarHBondContact O-N 3.09Å; L150-L153 VanDerWaalsContact O-N 3.16Å; L150-L154 WeakPolarHBondContact O-CB 3.4Å; L150-L154 PolarHBondContact O-N 2.61Å; L150-L171 HydrophobicContact CB-CD2 4.2Å; L150-L171 HydrophobicContact CD2-CB 3.61Å; L150-L171 HydrophobicContact CD2-CD1 4.18Å; L150-L171 HydrophobicContact CD2-CD2 3.68Å; L150-L171 HydrophobicContact CD2-CG 4.01Å
151	V	67.4	Low	68.3	Low	5 Å²	5	70.4 Å²	70.4	3%	0.03	35%	0.349	C	S	.	.	H	α-helix	trans	-62.9	-43.4	177.1	176.3	0	0	0	0	110.6	C147 I148 L153 L154 I155 V168 F432	C147-V151 PolarHBondContact O-N 3.09Å; I148-V151 PolarHBondContact O-N 3.41Å; V151-L153 VanDerWaalsContact C-N 3.31Å; V151-L153 PolarHBondContact O-N 2.95Å; V151-L154 WeakPolarHBondContact O-CB 3.24Å; V151-L154 PolarHBondContact O-N 3.34Å; V151-I155 HydrophobicContact CG1-CD1 4.04Å; V151-I155 WeakPolarHBondContact O-CD1 3.45Å; V151-I155 VanDerWaalsContact O-CG1 3.29Å; V151-I155 WeakPolarHBondContact O-CG1 3.09Å; V151-I155 PolarHBondContact O-N 3.05Å; V151-I155 VanDerWaalsContact O-N 3.15Å; V151-V168 HydrophobicContact CG2-CG2 3.63Å; V151-F432 HydrophobicContact CG1-CZ 4.15Å
152	H	72.8	Confident	68	Low	130 Å²	130	68.3 Å²	68.3	60%	0.602	34%	0.338	S	S	*	.	H	α-helix	trans	-58.9	-41.8	172.4	-179.4	84.4	0	0	0	112.2	I148 I149 L150 I155 K156	I148-H152 PolarHBondContact O-N 3.33Å; I149-H152 PolarHBondContact O-N 2.82Å; L150-H152 VanDerWaalsContact C-N 3.35Å; L150-H152 PolarHBondContact O-N 3.07Å; H152-I155 PolarHBondContact O-N 3.27Å; H152-K156 WeakPolarHBondContact O-CB 3.33Å; H152-K156 PolarHBondContact O-N 2.97Å
153	L	73.1	Confident	67.9	Low	67 Å²	67	65.9 Å²	65.9	35%	0.351	33%	0.326	S	S	.	.	H	α-helix	trans	-62.4	-42.7	177	-153.7	86.8	0	0	0	112	I149 L150 V151 I155 K156 F157	I149-L153 WeakPolarHBondContact O-CB 3.33Å; I149-L153 PolarHBondContact O-N 3.3Å; L150-L153 HydrophobicContact CD1-CD2 4.34Å; L150-L153 WeakPolarHBondContact O-CB 3.32Å; L150-L153 PolarHBondContact O-N 3.09Å; L150-L153 VanDerWaalsContact O-N 3.16Å; V151-L153 VanDerWaalsContact C-N 3.31Å; V151-L153 PolarHBondContact O-N 2.95Å; L153-I155 VanDerWaalsContact C-N 3.32Å; L153-I155 PolarHBondContact O-N 3.06Å; L153-K156 PolarHBondContact O-N 2.82Å; L153-F157 HydrophobicContact CD1-CE2 4.07Å; L153-F157 HydrophobicContact CD2-CD2 4.15Å; L153-F157 HydrophobicContact CD2-CE2 3.9Å; L153-F157 HydrophobicContact CG-CD2 3.78Å; L153-F157 HydrophobicContact CG-CE2 3.66Å; L153-F157 WeakPolarHBondContact O-CD2 3.48Å; L153-F157 PolarHBondContact O-N 3.34Å
154	L	67.9	Low	68.1	Low	23 Å²	23	65.9 Å²	65.9	12%	0.12	32%	0.324	C	S	.	.	H	α-helix	trans	-60.5	-42	178.8	-161.9	85	0	0	0	111.7	L150 V151 K158 L159 A167	L150-L154 WeakPolarHBondContact O-CB 3.4Å; L150-L154 PolarHBondContact O-N 2.61Å; V151-L154 WeakPolarHBondContact O-CB 3.24Å; V151-L154 PolarHBondContact O-N 3.34Å; L154-K158 PolarHBondContact O-N 2.91Å; L154-L159 HydrophobicContact CD1-CB 4.43Å; L154-L159 HydrophobicContact CD1-CD1 4.01Å; L154-A167 HydrophobicContact CD1-CB 3.83Å; L154-A167 HydrophobicContact CD2-CB 3.65Å; L154-A167 HydrophobicContact CG-CB 4.35Å
155	I	65.1	Low	68.4	Low	31 Å²	31	65 Å²	65	16%	0.159	32%	0.319	C	S	.	.	H	α-helix	trans	-65.5	-48.8	176.2	-64	161.2	0	0	0	110.1	V151 H152 L153 F157 K158 T570 Q571	V151-I155 HydrophobicContact CG1-CD1 4.04Å; V151-I155 WeakPolarHBondContact O-CD1 3.45Å; V151-I155 VanDerWaalsContact O-CG1 3.29Å; V151-I155 WeakPolarHBondContact O-CG1 3.09Å; V151-I155 PolarHBondContact O-N 3.05Å; V151-I155 VanDerWaalsContact O-N 3.15Å; H152-I155 PolarHBondContact O-N 3.27Å; L153-I155 VanDerWaalsContact C-N 3.32Å; L153-I155 PolarHBondContact O-N 3.06Å; I155-F157 VanDerWaalsContact C-N 3.32Å; I155-F157 PolarHBondContact O-N 3.39Å; I155-K158 PolarHBondContact O-N 3.01Å; I155-K158 VanDerWaalsContact O-N 3.14Å; I155-T570 HydrophobicContact CD1-CG2 3.87Å; I155-Q571 HydrophobicContact CG2-CB 3.93Å; I155-Q571 HydrophobicContact CG2-CG 4.03Å
156	K	70	Confident	68.5	Low	113 Å²	113	64.3 Å²	64.3	49%	0.491	31%	0.31	S	S	.	.	H	α-helix	trans	-58.9	-41	178.6	-175.5	-175.6	173.6	-170.6	0	112.4	D24 H152 L153 K158	D24-K156 IonicContact OD2-NZ 2.81Å; D24-K156 PolarHBondContact OD2-NZ 3.18Å; H152-K156 WeakPolarHBondContact O-CB 3.33Å; H152-K156 PolarHBondContact O-N 2.97Å; L153-K156 PolarHBondContact O-N 2.82Å; K156-K158 VanDerWaalsContact C-N 3.28Å; K156-K158 PolarHBondContact O-N 2.86Å
157	F	71.5	Confident	68.7	Low	131 Å²	131	61.4 Å²	61.4	58%	0.575	30%	0.296	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.7	1.3	179.3	-79.6	-60.3	0	0	0	115.1	L153 I155 L159	L153-F157 HydrophobicContact CD1-CE2 4.07Å; L153-F157 HydrophobicContact CD2-CD2 4.15Å; L153-F157 HydrophobicContact CD2-CE2 3.9Å; L153-F157 HydrophobicContact CG-CD2 3.78Å; L153-F157 HydrophobicContact CG-CE2 3.66Å; L153-F157 WeakPolarHBondContact O-CD2 3.48Å; L153-F157 PolarHBondContact O-N 3.34Å; I155-F157 VanDerWaalsContact C-N 3.32Å; I155-F157 PolarHBondContact O-N 3.39Å; F157-L159 VanDerWaalsContact C-N 3.3Å; F157-L159 HydrophobicContact CB-CG 4.29Å; F157-L159 PolarHBondContact O-N 3.26Å
158	K	58.6	Low	69.3	Low	139 Å²	139	61.3 Å²	61.3	60%	0.604	30%	0.295	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.9	44.7	176.6	-73.6	-167.8	173.9	-170.4	0	113.5	L154 I155 K156 H160	L154-K158 PolarHBondContact O-N 2.91Å; I155-K158 PolarHBondContact O-N 3.01Å; I155-K158 VanDerWaalsContact O-N 3.14Å; K156-K158 VanDerWaalsContact C-N 3.28Å; K156-K158 PolarHBondContact O-N 2.86Å; K158-H160 PolarHBondContact O-CD2 3.17Å; K158-H160 PolarHBondContact O-N 3.19Å
159	L	59.3	Low	69.8	Low	96 Å²	96	58.1 Å²	58.1	50%	0.503	28%	0.279	S	S	.	.			trans	-78.8	66.9	176.1	-66.3	179.8	0	0	0	111.4	L154 F157 F161 L162	L154-L159 HydrophobicContact CD1-CB 4.43Å; L154-L159 HydrophobicContact CD1-CD1 4.01Å; F157-L159 VanDerWaalsContact C-N 3.3Å; F157-L159 HydrophobicContact CB-CG 4.29Å; F157-L159 PolarHBondContact O-N 3.26Å; L159-F161 PolarHBondContact O-N 3.4Å; L159-L162 PolarHBondContact O-N 3.28Å
160	H	56.3	Low	70	Confident	66 Å²	66	55.6 Å²	55.6	31%	0.306	27%	0.27	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.9	10.6	-176.2	-67.5	-89.8	0	0	0	116.3	K158 M544 V565 N566 L567	K158-H160 PolarHBondContact O-CD2 3.17Å; K158-H160 PolarHBondContact O-N 3.19Å; H160-M544 WeakPolarHBondContact O-CE 3.45Å; H160-V565 PolarHBondContact ND1-O 3.34Å; H160-N566 PolarHBondContact CE1-OD1 3.48Å; H160-N566 VanDerWaalsContact CE1-OD1 3.31Å; H160-L567 VanDerWaalsContact O-CD1 3.24Å; H160-L567 WeakPolarHBondContact O-CD1 3.24Å
161	F	59.9	Low	70.5	Confident	135 Å²	135	54.8 Å²	54.8	59%	0.592	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-115	-10.9	-178	-162	-102.4	0	0	0	113.7	L159	L159-F161 PolarHBondContact O-N 3.4Å
162	L	63	Low	71.1	Confident	73 Å²	73	54.7 Å²	54.7	38%	0.382	27%	0.266	S	S	.	.	S	Bend	trans	-118.5	122.7	-177.7	-64.1	177.2	0	0	0	111.1	L159 V166	L159-L162 PolarHBondContact O-N 3.28Å; L162-V166 HydrophobicContact CD2-CG1 4.1Å
163	P	68.3	Low	71.6	Confident	7 Å²	7	50.6 Å²	50.6	5%	0.045	25%	0.248	C	C	.	.			trans	-60.1	149.8	167.1	-23.2	33.6	0	0	0	112.3	S165 V166 A167 A279	P163-S165 VanDerWaalsContact C-N 3.32Å; P163-S165 PolarHBondContact O-N 3.13Å; P163-V166 HydrophobicContact CB-CG2 4.18Å; P163-V166 HydrophobicContact CG-CG2 4.14Å; P163-V166 WeakPolarHBondContact O-CB 3.39Å; P163-V166 PolarHBondContact O-N 3.48Å; P163-A167 PolarHBondContact O-N 2.91Å; P163-A279 HydrophobicContact CB-CB 3.85Å; P163-A279 HydrophobicContact CG-CB 4.15Å
164	E	71.8	Confident	72	Confident	20 Å²	20	53.3 Å²	53.3	9%	0.093	26%	0.263	C	S	.	.	H	α-helix	trans	-55.6	-44.4	-179.2	-68.4	161.4	164.8	0	0	112.1	V166 A167 V168 S568 K569 T570	E164-V166 VanDerWaalsContact C-N 3.27Å; E164-V166 PolarHBondContact O-N 3.37Å; E164-A167 WeakPolarHBondContact O-CB 3.46Å; E164-A167 PolarHBondContact O-N 3.13Å; E164-A167 VanDerWaalsContact O-N 3.13Å; E164-V168 WeakPolarHBondContact O-CG2 3.25Å; E164-V168 PolarHBondContact O-N 2.87Å; E164-S568 WeakPolarHBondContact OE1-CA 3.36Å; E164-S568 WeakPolarHBondContact OE1-CB 3.36Å; E164-S568 PolarHBondContact OE1-OG 3.05Å; E164-K569 PolarHBondContact OE1-N 3.17Å; E164-K569 VanDerWaalsContact OE2-CB 3.31Å; E164-K569 WeakPolarHBondContact OE2-CB 3.45Å; E164-K569 PolarHBondContact OE2-N 3.46Å; E164-T570 PolarHBondContact OE1-N 3.19Å; E164-T570 PolarHBondContact OE1-OG1 3.47Å
165	S	74.8	Confident	72.4	Confident	9 Å²	9	54.2 Å²	54.2	6%	0.063	27%	0.266	C	S	.	.	H	α-helix	trans	-57.8	-36.2	176.3	-45.5	0	0	0	0	113.2	P163 V168 V169 V278 F439	P163-S165 VanDerWaalsContact C-N 3.32Å; P163-S165 PolarHBondContact O-N 3.13Å; S165-V168 PolarHBondContact O-N 3.16Å; S165-V169 WeakPolarHBondContact O-CB 3.49Å; S165-V169 VanDerWaalsContact O-CG2 3.29Å; S165-V169 WeakPolarHBondContact O-CG2 3.47Å; S165-V169 PolarHBondContact O-N 2.88Å; S165-V278 WeakPolarHBondContact OG-CG1 3.24Å; S165-F439 WeakPolarHBondContact OG-CE2 3.41Å
166	V	76.9	Confident	72.9	Confident	13 Å²	13	52.8 Å²	52.8	8%	0.079	26%	0.26	C	S	.	.	H	α-helix	trans	-66.4	-43.3	177.6	171.4	0	0	0	0	110.3	L162 P163 E164 S170 I536 L537	L162-V166 HydrophobicContact CD2-CG1 4.1Å; P163-V166 HydrophobicContact CB-CG2 4.18Å; P163-V166 HydrophobicContact CG-CG2 4.14Å; P163-V166 WeakPolarHBondContact O-CB 3.39Å; P163-V166 PolarHBondContact O-N 3.48Å; E164-V166 VanDerWaalsContact C-N 3.27Å; E164-V166 PolarHBondContact O-N 3.37Å; V166-S170 WeakPolarHBondContact O-CB 3.5Å; V166-S170 PolarHBondContact O-N 3.24Å; V166-S170 PolarHBondContact O-OG 2.9Å; V166-I536 HydrophobicContact CG2-CG2 3.69Å; V166-L537 HydrophobicContact CB-CD2 4.48Å; V166-L537 HydrophobicContact CG1-CD2 3.62Å; V166-L537 HydrophobicContact CG2-CD2 4.32Å
167	A	78.8	Confident	73.4	Confident	4 Å²	4	48.1 Å²	48.1	3%	0.033	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-46.8	177.1	0	0	0	0	0	111.5	L154 P163 E164 S170 L171	L154-A167 HydrophobicContact CD1-CB 3.83Å; L154-A167 HydrophobicContact CD2-CB 3.65Å; L154-A167 HydrophobicContact CG-CB 4.35Å; P163-A167 PolarHBondContact O-N 2.91Å; E164-A167 WeakPolarHBondContact O-CB 3.46Å; E164-A167 PolarHBondContact O-N 3.13Å; E164-A167 VanDerWaalsContact O-N 3.13Å; A167-S170 PolarHBondContact O-N 2.96Å; A167-S170 PolarHBondContact O-OG 3.14Å; A167-L171 PolarHBondContact O-N 2.93Å
168	V	80.6	Confident	73.7	Confident	4 Å²	4	46.5 Å²	46.5	2%	0.024	24%	0.236	C	C	.	.	H	α-helix	trans	-63.6	-45	179.6	177.6	0	0	0	0	112	V151 E164 S165 S170 L171 G172 T436 F439 A440	V151-V168 HydrophobicContact CG2-CG2 3.63Å; E164-V168 WeakPolarHBondContact O-CG2 3.25Å; E164-V168 PolarHBondContact O-N 2.87Å; S165-V168 PolarHBondContact O-N 3.16Å; V168-S170 VanDerWaalsContact C-N 3.33Å; V168-S170 PolarHBondContact O-N 3.25Å; V168-L171 PolarHBondContact O-N 3.38Å; V168-G172 PolarHBondContact O-N 3.28Å; V168-T436 HydrophobicContact CG1-CG2 4.04Å; V168-T436 WeakPolarHBondContact CG1-O 3.5Å; V168-T436 HydrophobicContact CG2-CG2 4.2Å; V168-F439 HydrophobicContact CB-CB 4.19Å; V168-F439 HydrophobicContact CG1-CB 3.71Å; V168-A440 HydrophobicContact CG1-CB 4.03Å
169	V	81.6	Confident	74.3	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.006	21%	0.211	C	C	.	.	H	α-helix	trans	-60.3	-43.2	173.7	170.7	0	0	0	0	110.7	S165 L171 G172 I173 F439 L442 L533	S165-V169 WeakPolarHBondContact O-CB 3.49Å; S165-V169 VanDerWaalsContact O-CG2 3.29Å; S165-V169 WeakPolarHBondContact O-CG2 3.47Å; S165-V169 PolarHBondContact O-N 2.88Å; V169-L171 VanDerWaalsContact C-N 3.32Å; V169-L171 PolarHBondContact O-N 3.28Å; V169-G172 PolarHBondContact O-N 2.58Å; V169-G172 VanDerWaalsContact O-N 3.17Å; V169-I173 HydrophobicContact CG1-CD1 3.94Å; V169-I173 HydrophobicContact CG1-CG1 4.45Å; V169-I173 WeakPolarHBondContact O-CG1 3.47Å; V169-I173 PolarHBondContact O-N 3.05Å; V169-F439 HydrophobicContact CG2-CB 3.93Å; V169-F439 HydrophobicContact CG2-CD1 3.83Å; V169-F439 HydrophobicContact CG2-CG 4.27Å; V169-L442 HydrophobicContact CG1-CD2 4.02Å; V169-L442 HydrophobicContact CG2-CD2 3.94Å; V169-L533 HydrophobicContact CG1-CD1 3.69Å
170	S	81.9	Confident	75.1	Confident	52 Å²	52	40.4 Å²	40.4	36%	0.364	21%	0.207	S	C	.	.	H	α-helix	trans	-62.8	-35	178.8	78.1	0	0	0	0	113.4	V166 A167 V168 I173 L174	V166-S170 WeakPolarHBondContact O-CB 3.5Å; V166-S170 PolarHBondContact O-N 3.24Å; V166-S170 PolarHBondContact O-OG 2.9Å; A167-S170 PolarHBondContact O-N 2.96Å; A167-S170 PolarHBondContact O-OG 3.14Å; V168-S170 VanDerWaalsContact C-N 3.33Å; V168-S170 PolarHBondContact O-N 3.25Å; S170-I173 PolarHBondContact O-N 3.38Å; S170-L174 WeakPolarHBondContact O-CG 3.42Å; S170-L174 PolarHBondContact O-N 3.39Å
171	L	80.3	Confident	76.1	Confident	31 Å²	31	42 Å²	42	16%	0.162	22%	0.216	C	C	.	.	H	α-helix	trans	-67.1	-43.6	172.6	177.5	65	0	0	0	111.8	I146 C147 L150 A167 V168 V169 I173 L174 M175	I146-L171 HydrophobicContact CG2-CD2 4.28Å; C147-L171 HydrophobicContact CB-CD2 4.21Å; L150-L171 HydrophobicContact CB-CD2 4.2Å; L150-L171 HydrophobicContact CD2-CB 3.61Å; L150-L171 HydrophobicContact CD2-CD1 4.18Å; L150-L171 HydrophobicContact CD2-CD2 3.68Å; L150-L171 HydrophobicContact CD2-CG 4.01Å; A167-L171 PolarHBondContact O-N 2.93Å; V168-L171 PolarHBondContact O-N 3.38Å; V169-L171 VanDerWaalsContact C-N 3.32Å; V169-L171 PolarHBondContact O-N 3.28Å; L171-I173 VanDerWaalsContact C-N 3.27Å; L171-I173 PolarHBondContact O-N 3.2Å; L171-L174 PolarHBondContact O-N 2.91Å; L171-M175 WeakPolarHBondContact O-CB 3.44Å; L171-M175 PolarHBondContact O-N 3.01Å
172	G	81	Confident	76.8	Confident	3 Å²	3	37.3 Å²	37.3	3%	0.031	20%	0.197	C	C	.	.	H	α-helix	trans	-57.4	-41.7	174.8	0	0	0	0	0	112.1	V168 V169 M175 G176 G443 L444	V168-G172 PolarHBondContact O-N 3.28Å; V169-G172 PolarHBondContact O-N 2.58Å; V169-G172 VanDerWaalsContact O-N 3.17Å; G172-M175 PolarHBondContact O-N 3.32Å; G172-G176 PolarHBondContact O-N 3.47Å; G172-G443 CarbonylContact O-C 3.59Å; G172-L444 WeakPolarHBondContact O-CA 3.34Å; G172-L444 PolarHBondContact O-N 3.14Å
173	I	83.1	Confident	77.1	Confident	44 Å²	44	36.5 Å²	36.5	23%	0.226	19%	0.191	C	C	.	.	H	α-helix	trans	-61.7	-49.6	174.7	-68.5	172	0	0	0	110.7	V169 S170 L171 M175 G176 G177 G443 I446 F447 L533	V169-I173 HydrophobicContact CG1-CD1 3.94Å; V169-I173 HydrophobicContact CG1-CG1 4.45Å; V169-I173 WeakPolarHBondContact O-CG1 3.47Å; V169-I173 PolarHBondContact O-N 3.05Å; S170-I173 PolarHBondContact O-N 3.38Å; L171-I173 VanDerWaalsContact C-N 3.27Å; L171-I173 PolarHBondContact O-N 3.2Å; I173-M175 VanDerWaalsContact C-N 3.34Å; I173-M175 PolarHBondContact O-N 3.46Å; I173-G176 PolarHBondContact O-N 3.2Å; I173-G177 PolarHBondContact O-N 3.34Å; I173-G443 WeakPolarHBondContact CA-O 3.5Å; I173-I446 HydrophobicContact CD1-CD1 3.87Å; I173-I446 HydrophobicContact CG1-CD1 3.92Å; I173-I446 HydrophobicContact CG1-CG1 4.41Å; I173-F447 HydrophobicContact CG2-CE2 3.82Å; I173-F447 WeakPolarHBondContact O-CD2 3.46Å; I173-F447 WeakPolarHBondContact O-CE2 3.39Å; I173-L533 HydrophobicContact CD1-CD1 3.92Å; I173-L533 HydrophobicContact CD1-CD2 4.48Å
174	L	82.1	Confident	77.2	Confident	125 Å²	125	44.8 Å²	44.8	65%	0.654	23%	0.227	S	C	*	.	H	α-helix	trans	-61.3	-40.9	177.8	-71.5	170.7	0	0	0	112.4	S170 L171 G177 F178	S170-L174 WeakPolarHBondContact O-CG 3.42Å; S170-L174 PolarHBondContact O-N 3.39Å; L171-L174 PolarHBondContact O-N 2.91Å; L174-G177 PolarHBondContact O-N 2.96Å; L174-F178 WeakPolarHBondContact O-CB 3.26Å; L174-F178 PolarHBondContact O-N 2.98Å
175	M	75.8	Confident	77.3	Confident	41 Å²	41	49.6 Å²	49.6	20%	0.202	25%	0.249	C	C	.	.	H	α-helix	trans	-65.9	-45.3	177.1	178.3	-176.6	153.4	0	0	111.9	F139 V143 L171 G172 I173 G177 F178 I179 L444	F139-M175 HydrophobicContact CE1-CE 4.14Å; V143-M175 HydrophobicContact CB-CE 4.26Å; V143-M175 HydrophobicContact CB-SD 4.3Å; V143-M175 HydrophobicContact CG1-CE 3.79Å; V143-M175 HydrophobicContact CG1-SD 3.51Å; V143-M175 VanDerWaalsContact CG1-SD 3.51Å; V143-M175 HydrophobicContact CG2-CE 3.43Å; V143-M175 VanDerWaalsContact CG2-CE 3.43Å; V143-M175 HydrophobicContact CG2-SD 3.78Å; L171-M175 WeakPolarHBondContact O-CB 3.44Å; L171-M175 PolarHBondContact O-N 3.01Å; G172-M175 PolarHBondContact O-N 3.32Å; I173-M175 VanDerWaalsContact C-N 3.34Å; I173-M175 PolarHBondContact O-N 3.46Å; M175-G177 VanDerWaalsContact C-N 3.34Å; M175-G177 PolarHBondContact O-N 2.79Å; M175-F178 WeakPolarHBondContact O-CB 3.46Å; M175-F178 PolarHBondContact O-N 3.27Å; M175-I179 HydrophobicContact CE-CD1 3.6Å; M175-I179 HydrophobicContact CG-CD1 3.98Å; M175-I179 WeakPolarHBondContact O-CG1 3.48Å; M175-I179 PolarHBondContact O-N 3.17Å; M175-L444 HydrophobicContact CE-CD2 4.39Å
176	G	75.7	Confident	76.7	Confident	2 Å²	2	57.3 Å²	57.3	2%	0.021	28%	0.284	C	S	.	.	H	α-helix	trans	-62.8	-39.9	176.1	0	0	0	0	0	112.6	G172 I173 F178 I179 K180 L444 F447	G172-G176 PolarHBondContact O-N 3.47Å; I173-G176 PolarHBondContact O-N 3.2Å; G176-F178 VanDerWaalsContact C-N 3.34Å; G176-F178 PolarHBondContact O-N 3.03Å; G176-I179 PolarHBondContact O-N 3.37Å; G176-K180 WeakPolarHBondContact O-CB 3.27Å; G176-K180 PolarHBondContact O-N 3.35Å; G176-L444 VanDerWaalsContact CA-CD1 3.5Å; G176-F447 VanDerWaalsContact C-CB 3.49Å; G176-F447 WeakPolarHBondContact O-CB 3.42Å
177	G	80	Confident	75.7	Confident	15 Å²	15	60.7 Å²	60.7	16%	0.155	30%	0.302	C	S	.	.	H	α-helix	trans	-61.4	-42.2	172.7	0	0	0	0	0	112.2	I173 L174 M175 K180 I181	I173-G177 PolarHBondContact O-N 3.34Å; L174-G177 PolarHBondContact O-N 2.96Å; M175-G177 VanDerWaalsContact C-N 3.34Å; M175-G177 PolarHBondContact O-N 2.79Å; G177-K180 PolarHBondContact O-N 3.47Å; G177-I181 WeakPolarHBondContact O-CD1 3.25Å; G177-I181 VanDerWaalsContact O-CG1 3.28Å; G177-I181 WeakPolarHBondContact O-CG1 3.4Å; G177-I181 PolarHBondContact O-N 3.47Å
178	F	77.1	Confident	74.6	Confident	96 Å²	96	62.2 Å²	62.2	42%	0.421	31%	0.314	S	S	.	.	H	α-helix	trans	-65.3	-42.3	176.7	-175.5	-108.8	0	0	0	112.9	F9 L174 M175 G176 I181 I182	F9-F178 AromaticContact CE1-CZ 3.93Å; F9-F178 HydrophobicContact CE1-CZ 3.93Å; F9-F178 HydrophobicContact CZ-CZ 4.18Å; L174-F178 WeakPolarHBondContact O-CB 3.26Å; L174-F178 PolarHBondContact O-N 2.98Å; M175-F178 WeakPolarHBondContact O-CB 3.46Å; M175-F178 PolarHBondContact O-N 3.27Å; G176-F178 VanDerWaalsContact C-N 3.34Å; G176-F178 PolarHBondContact O-N 3.03Å; F178-I181 PolarHBondContact O-N 3.03Å; F178-I182 HydrophobicContact CD1-CD1 3.93Å; F178-I182 HydrophobicContact CE1-CD1 3.45Å; F178-I182 VanDerWaalsContact CE1-CD1 3.45Å; F178-I182 HydrophobicContact CZ-CD1 3.79Å; F178-I182 PolarHBondContact O-N 3.46Å; F178-I182 VanDerWaalsContact O-N 3.11Å
179	I	72.9	Confident	73.2	Confident	14 Å²	14	69.2 Å²	69.2	7%	0.072	35%	0.351	C	S	.	.	H	α-helix	trans	-61.9	-44.2	175.1	-70.5	166.7	0	0	0	110.6	M175 G176 I181 I182 E183 E194 L444	M175-I179 HydrophobicContact CE-CD1 3.6Å; M175-I179 HydrophobicContact CG-CD1 3.98Å; M175-I179 WeakPolarHBondContact O-CG1 3.48Å; M175-I179 PolarHBondContact O-N 3.17Å; G176-I179 PolarHBondContact O-N 3.37Å; I179-I181 VanDerWaalsContact C-N 3.29Å; I179-I181 PolarHBondContact O-N 3.38Å; I179-I182 CarbonylContact O-C 3.23Å; I179-I182 WeakPolarHBondContact O-CA 3.31Å; I179-I182 WeakPolarHBondContact O-CB 3.35Å; I179-I182 PolarHBondContact O-N 3.2Å; I179-E183 PolarHBondContact O-N 2.74Å; I179-E194 HydrophobicContact CG2-CG 4.29Å; I179-E194 VanDerWaalsContact CG2-OE1 3.31Å; I179-E194 WeakPolarHBondContact CG2-OE1 3.26Å; I179-L444 HydrophobicContact CD1-CD1 3.92Å
180	K	74.3	Confident	72	Confident	94 Å²	94	72 Å²	72	41%	0.409	36%	0.362	S	S	.	.	H	α-helix	trans	-64	-32.1	177.7	-161.7	165.6	-161.6	148.7	0	113.3	G176 G177 I182 F184 F447	G176-K180 WeakPolarHBondContact O-CB 3.27Å; G176-K180 PolarHBondContact O-N 3.35Å; G177-K180 PolarHBondContact O-N 3.47Å; K180-I182 VanDerWaalsContact C-N 3.34Å; K180-F184 WeakPolarHBondContact O-CB 3.18Å; K180-F184 PolarHBondContact O-N 3.04Å; K180-F447 HydrophobicContact CD-CB 4.2Å; K180-F447 HydrophobicContact CD-CD1 3.88Å; K180-F447 PolarHBondContact NZ-O 3.47Å
181	I	78.8	Confident	70.4	Confident	99 Å²	99	75.8 Å²	75.8	51%	0.508	37%	0.372	S	S	.	.	H	α-helix	trans	-68.4	-33.2	171.5	-69.1	162.9	0	0	0	111.4	G177 F178 I179 Q185	G177-I181 WeakPolarHBondContact O-CD1 3.25Å; G177-I181 VanDerWaalsContact O-CG1 3.28Å; G177-I181 WeakPolarHBondContact O-CG1 3.4Å; G177-I181 PolarHBondContact O-N 3.47Å; F178-I181 PolarHBondContact O-N 3.03Å; I179-I181 VanDerWaalsContact C-N 3.29Å; I179-I181 PolarHBondContact O-N 3.38Å; I181-Q185 WeakPolarHBondContact O-CG 3.46Å; I181-Q185 PolarHBondContact O-N 3.34Å
182	I	73.4	Confident	68.8	Low	37 Å²	37	82.7 Å²	82.7	19%	0.19	40%	0.403	C	S	.	.	H	α-helix	trans	-73.3	-40.1	174.7	-71	174.2	0	0	0	111.7	F178 I179 K180 F184 Q185 L187	F178-I182 HydrophobicContact CD1-CD1 3.93Å; F178-I182 HydrophobicContact CE1-CD1 3.45Å; F178-I182 VanDerWaalsContact CE1-CD1 3.45Å; F178-I182 HydrophobicContact CZ-CD1 3.79Å; F178-I182 PolarHBondContact O-N 3.46Å; F178-I182 VanDerWaalsContact O-N 3.11Å; I179-I182 CarbonylContact O-C 3.23Å; I179-I182 WeakPolarHBondContact O-CA 3.31Å; I179-I182 WeakPolarHBondContact O-CB 3.35Å; I179-I182 PolarHBondContact O-N 3.2Å; K180-I182 VanDerWaalsContact C-N 3.34Å; I182-F184 VanDerWaalsContact C-N 3.34Å; I182-Q185 PolarHBondContact O-N 2.98Å; I182-L187 HydrophobicContact CG2-CB 4.06Å; I182-L187 PolarHBondContact O-N 2.94Å
183	E	69.6	Low	67.4	Low	56 Å²	56	86.8 Å²	86.8	26%	0.262	42%	0.421	S	S	.	.	H	α-helix	trans	-58.1	-47.5	171.9	-170.7	-170.6	-152.6	0	0	110.2	I179 Q185 E186 K191	I179-E183 PolarHBondContact O-N 2.74Å; E183-Q185 PolarHBondContact O-N 3.11Å; E183-Q185 VanDerWaalsContact O-N 3.13Å; E183-E186 PolarHBondContact O-N 2.99Å; E183-K191 IonicContact OE1-NZ 3.41Å; E183-K191 PolarHBondContact OE1-NZ 3.26Å
184	F	70.3	Confident	65.8	Low	181 Å²	181	86 Å²	86	79%	0.794	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.2	-18.7	177.7	-174.5	-97.9	0	0	0	114.4	K180 I182	K180-F184 WeakPolarHBondContact O-CB 3.18Å; K180-F184 PolarHBondContact O-N 3.04Å; I182-F184 VanDerWaalsContact C-N 3.34Å
185	Q	74.1	Confident	64.4	Low	120 Å²	120	86.1 Å²	86.1	56%	0.561	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.4	8.7	174.4	-69.6	-173.2	-0	0	0	113.7	I181 I182 E183 L187	I181-Q185 WeakPolarHBondContact O-CG 3.46Å; I181-Q185 PolarHBondContact O-N 3.34Å; I182-Q185 PolarHBondContact O-N 2.98Å; E183-Q185 PolarHBondContact O-N 3.11Å; E183-Q185 VanDerWaalsContact O-N 3.13Å; Q185-L187 HydrophobicContact CB-CD1 3.97Å; Q185-L187 HydrophobicContact CB-CG 3.85Å; Q185-L187 PolarHBondContact O-N 3.07Å
186	E	62.3	Low	63.6	Low	171 Å²	171	85.4 Å²	85.4	80%	0.799	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	53.2	22.3	-176.7	-60.2	-167.7	149.7	0	0	114.5	E183	E183-E186 PolarHBondContact O-N 2.99Å
187	L	56.7	Low	63	Low	85 Å²	85	93.9 Å²	93.9	45%	0.445	44%	0.443	S	S	.	.	S	Bend	trans	-74.6	-31.6	-172.1	-70.2	176.2	0	0	0	112.7	I182 Q185	I182-L187 HydrophobicContact CG2-CB 4.06Å; I182-L187 PolarHBondContact O-N 2.94Å; Q185-L187 HydrophobicContact CB-CD1 3.97Å; Q185-L187 HydrophobicContact CB-CG 3.85Å; Q185-L187 PolarHBondContact O-N 3.07Å
188	A	54.3	Low	62.4	Low	36 Å²	36	94.8 Å²	94.8	30%	0.298	45%	0.446	S	S	.	.			trans	-164.1	147.2	171.5	0	0	0	0	0	111.6	W190	A188-W190 PolarHBondContact O-N 3.04Å
189	N	51.5	Low	62.1	Low	150 Å²	150	95.1 Å²	95.1	80%	0.802	45%	0.452	S	S	*	.			trans	-88.7	93.4	171.6	-83.5	-18.9	0	0	0	110.2	K191	N189-K191 VanDerWaalsContact C-N 3.27Å
190	W	56.8	Low	62.2	Low	61 Å²	61	99.5 Å²	99.5	23%	0.231	47%	0.474	C	S	.	.			trans	-84.9	0.3	175	-64.1	99.6	0	0	0	113.9	A188 E192 E193 E194	A188-W190 PolarHBondContact O-N 3.04Å; W190-E192 VanDerWaalsContact C-N 3.25Å; W190-E192 PolarHBondContact O-N 3.04Å; W190-E193 WeakPolarHBondContact CZ3-OE2 3.48Å; W190-E193 PolarHBondContact O-N 3.47Å; W190-E194 HydrophobicContact CB-CG 4.14Å; W190-E194 WeakPolarHBondContact CB-OE1 3.3Å; W190-E194 PolarHBondContact O-N 2.75Å
191	K	48.3	Very low	62.3	Low	131 Å²	131	95.1 Å²	95.1	57%	0.57	46%	0.455	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.8	-25.5	-165.2	-144.8	-179.2	-163.1	87.8	0	116.5	E183 N189	E183-K191 IonicContact OE1-NZ 3.41Å; E183-K191 PolarHBondContact OE1-NZ 3.26Å; N189-K191 VanDerWaalsContact C-N 3.27Å
192	E	47.1	Very low	62.1	Low	175 Å²	175	91 Å²	91	82%	0.818	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95	-17.1	176.2	-64.5	-164	177.4	0	0	113.9	W190	W190-E192 VanDerWaalsContact C-N 3.25Å; W190-E192 PolarHBondContact O-N 3.04Å
193	E	50.2	Low	62.4	Low	89 Å²	89	93.5 Å²	93.5	42%	0.416	45%	0.446	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.7	-31.9	174.9	-64.1	-164.8	179	0	0	112.4	S136 W190 M195	S136-E193 VanDerWaalsContact CB-CD 3.45Å; S136-E193 WeakPolarHBondContact CB-OE1 3.16Å; S136-E193 WeakPolarHBondContact CB-OE2 3.4Å; S136-E193 PolarHBondContact OG-OE1 3.01Å; W190-E193 WeakPolarHBondContact CZ3-OE2 3.48Å; W190-E193 PolarHBondContact O-N 3.47Å; E193-M195 PolarHBondContact O-N 3.13Å
194	E	50.4	Low	63	Low	29 Å²	29	95.7 Å²	95.7	14%	0.136	46%	0.459	C	S	.	.	S	Bend	trans	-64.7	-25.4	177.2	-67	172.8	-140.5	0	0	113.5	I179 W190 F196 S448	I179-E194 HydrophobicContact CG2-CG 4.29Å; I179-E194 VanDerWaalsContact CG2-OE1 3.31Å; I179-E194 WeakPolarHBondContact CG2-OE1 3.26Å; W190-E194 HydrophobicContact CB-CG 4.14Å; W190-E194 WeakPolarHBondContact CB-OE1 3.3Å; W190-E194 PolarHBondContact O-N 2.75Å; E194-F196 PolarHBondContact O-N 2.91Å; E194-S448 VanDerWaalsContact CB-OG 3.27Å; E194-S448 WeakPolarHBondContact CB-OG 3.45Å; E194-S448 VanDerWaalsContact OE2-CB 3.23Å; E194-S448 WeakPolarHBondContact OE2-CB 3.26Å; E194-S448 PolarHBondContact OE2-OG 3.14Å
195	M	52.4	Low	63.7	Low	127 Å²	127	88 Å²	88	63%	0.626	43%	0.426	S	S	*	.	S	Bend	trans	-79.5	85.7	-170.2	-148.9	-178.8	75.1	0	0	111.6	E193 R197	E193-M195 PolarHBondContact O-N 3.13Å; M195-R197 PolarHBondContact O-N 3.45Å
196	F	59.4	Low	64.2	Low	26 Å²	26	82.3 Å²	82.3	11%	0.114	40%	0.4	C	S	.	.			trans	-41.2	107.1	175.9	179.4	-102.3	0	0	0	112.5	E194 P198 F201 L205 F441 L511	E194-F196 PolarHBondContact O-N 2.91Å; F196-P198 VanDerWaalsContact O-CD 3.25Å; F196-P198 WeakPolarHBondContact O-CD 3.33Å; F196-F201 HydrophobicContact CE1-CB 3.9Å; F196-F201 HydrophobicContact CZ-CB 3.69Å; F196-F201 AromaticContact CZ-CD2 3.99Å; F196-F201 HydrophobicContact CZ-CD2 3.99Å; F196-F201 HydrophobicContact CZ-CG 4.25Å; F196-L205 HydrophobicContact CE2-CD1 4.03Å; F196-L205 HydrophobicContact CZ-CD1 4.24Å; F196-F441 HydrophobicContact CD2-CB 4.08Å; F196-F441 HydrophobicContact CD2-CD1 4.16Å; F196-F441 AromaticContact CD2-CD2 3.74Å; F196-F441 HydrophobicContact CD2-CD2 3.74Å; F196-F441 HydrophobicContact CD2-CE2 4.18Å; F196-F441 AromaticContact CD2-CG 3.74Å; F196-F441 HydrophobicContact CD2-CG 3.74Å; F196-F441 HydrophobicContact CE2-CB 4.13Å; F196-F441 AromaticContact CE2-CD2 3.35Å; F196-F441 HydrophobicContact CE2-CD2 3.35Å; F196-F441 AromaticContact CE2-CE2 3.82Å; F196-F441 HydrophobicContact CE2-CE2 3.82Å; F196-F441 AromaticContact CE2-CG 3.8Å; F196-F441 HydrophobicContact CE2-CG 3.8Å; F196-F441 HydrophobicContact CZ-CD2 4.35Å; F196-L511 HydrophobicContact CD1-CD1 3.69Å; F196-L511 HydrophobicContact CE1-CD1 4.22Å
197	R	64.1	Low	65.5	Low	180 Å²	180	74.3 Å²	74.3	68%	0.679	36%	0.363	S	S	*	.			trans	-72.1	114	-177.2	-63.9	-172.6	-179.7	-142.5	-1.2	109.6	M195 N199 M200	M195-R197 PolarHBondContact O-N 3.45Å; R197-N199 PolarHBondContact O-N 3.09Å; R197-M200 HydrophobicContact CB-CG 4.26Å; R197-M200 WeakPolarHBondContact O-CB 3.32Å; R197-M200 PolarHBondContact O-N 3.46Å
198	P	65.7	Low	67.1	Low	34 Å²	34	71.8 Å²	71.8	22%	0.221	35%	0.351	C	S	.	.	H	α-helix	trans	-58.7	-29.9	-173.2	-26.9	37	0	0	0	113.5	F196 M200 F201 F202 L511 H512	F196-P198 VanDerWaalsContact O-CD 3.25Å; F196-P198 WeakPolarHBondContact O-CD 3.33Å; P198-M200 VanDerWaalsContact C-N 3.26Å; P198-M200 PolarHBondContact O-N 3.29Å; P198-F201 VanDerWaalsContact O-CB 3.3Å; P198-F201 WeakPolarHBondContact O-CB 3.24Å; P198-F201 PolarHBondContact O-N 3.21Å; P198-F202 WeakPolarHBondContact O-CD2 3.48Å; P198-F202 PolarHBondContact O-N 3.45Å; P198-L511 HydrophobicContact CB-CB 4.36Å; P198-L511 HydrophobicContact CG-CB 3.83Å; P198-H512 HydrophobicContact CB-CB 4.43Å
199	N	72.4	Confident	68.8	Low	103 Å²	103	71 Å²	71	55%	0.551	34%	0.342	S	S	*	.	H	α-helix	trans	-61.4	-32.6	176.8	-58.7	6.1	0	0	0	112.4	R197 F201 L203	R197-N199 PolarHBondContact O-N 3.09Å; N199-F201 VanDerWaalsContact C-N 3.31Å; N199-F201 PolarHBondContact O-N 3.25Å; N199-L203 WeakPolarHBondContact O-CB 3.4Å; N199-L203 WeakPolarHBondContact O-CD1 3.44Å; N199-L203 PolarHBondContact O-N 2.89Å
200	M	73.8	Confident	70.5	Confident	105 Å²	105	64 Å²	64	52%	0.517	31%	0.305	S	S	.	.	H	α-helix	trans	-67.8	-32.2	174.7	-70.2	-70.8	-77.1	0	0	111.6	R197 P198 L204 L205	R197-M200 HydrophobicContact CB-CG 4.26Å; R197-M200 WeakPolarHBondContact O-CB 3.32Å; R197-M200 PolarHBondContact O-N 3.46Å; P198-M200 VanDerWaalsContact C-N 3.26Å; P198-M200 PolarHBondContact O-N 3.29Å; M200-L204 HydrophobicContact CE-CD2 3.72Å; M200-L204 WeakPolarHBondContact O-CA 3.33Å; M200-L204 VanDerWaalsContact O-CB 3.26Å; M200-L204 WeakPolarHBondContact O-CB 3.31Å; M200-L204 PolarHBondContact O-N 3.46Å; M200-L205 PolarHBondContact O-N 3.48Å
201	F	76	Confident	72.2	Confident	3 Å²	3	61.3 Å²	61.3	1%	0.013	29%	0.294	C	S	.	.	I	π-helix	trans	-63.9	-56.6	173.2	-178	-99.6	0	0	0	111.3	F196 P198 N199 L203 L205 L206 V438 I505 A508	F196-F201 HydrophobicContact CE1-CB 3.9Å; F196-F201 HydrophobicContact CZ-CB 3.69Å; F196-F201 AromaticContact CZ-CD2 3.99Å; F196-F201 HydrophobicContact CZ-CD2 3.99Å; F196-F201 HydrophobicContact CZ-CG 4.25Å; P198-F201 VanDerWaalsContact O-CB 3.3Å; P198-F201 WeakPolarHBondContact O-CB 3.24Å; P198-F201 PolarHBondContact O-N 3.21Å; N199-F201 VanDerWaalsContact C-N 3.31Å; N199-F201 PolarHBondContact O-N 3.25Å; F201-L203 PolarHBondContact O-N 3.31Å; F201-L205 HydrophobicContact CD2-CB 4.23Å; F201-L205 HydrophobicContact CD2-CD1 4.42Å; F201-L205 PolarHBondContact O-N 2.66Å; F201-L205 VanDerWaalsContact O-N 3.1Å; F201-L206 HydrophobicContact CD1-CB 4.2Å; F201-L206 HydrophobicContact CD1-CD1 4.27Å; F201-L206 HydrophobicContact CE1-CB 3.87Å; F201-L206 HydrophobicContact CE1-CD1 3.39Å; F201-L206 HydrophobicContact CE1-CG 4.24Å; F201-L206 HydrophobicContact CZ-CB 4.1Å; F201-L206 HydrophobicContact CZ-CD1 3.86Å; F201-L206 WeakPolarHBondContact O-CB 3.31Å; F201-L206 PolarHBondContact O-N 3.43Å; F201-V438 HydrophobicContact CD2-CG2 3.86Å; F201-V438 HydrophobicContact CE2-CB 4.45Å; F201-V438 HydrophobicContact CE2-CG1 3.89Å; F201-V438 HydrophobicContact CE2-CG2 3.63Å; F201-I505 HydrophobicContact CZ-CG1 4.12Å; F201-A508 HydrophobicContact CB-CB 4.26Å; F201-A508 HydrophobicContact CD1-CB 3.28Å; F201-A508 HydrophobicContact CD2-CB 3.67Å; F201-A508 HydrophobicContact CE1-CB 3.28Å; F201-A508 HydrophobicContact CE2-CB 3.68Å; F201-A508 HydrophobicContact CG-CB 3.46Å; F201-A508 VanDerWaalsContact CG-CB 3.46Å; F201-A508 HydrophobicContact CZ-CB 3.49Å; F201-A508 VanDerWaalsContact CZ-CB 3.49Å
202	F	74.3	Confident	74.1	Confident	13 Å²	13	56.3 Å²	56.3	6%	0.057	27%	0.273	C	S	.	.	I	π-helix	trans	-71.9	-28.7	-169.9	-77.1	-72.6	0	0	0	114	P198 L206 P207 Y386 I397 A508 L509 H512	P198-F202 WeakPolarHBondContact O-CD2 3.48Å; P198-F202 PolarHBondContact O-N 3.45Å; F202-L206 HydrophobicContact CD1-CD1 4.27Å; F202-L206 HydrophobicContact CE1-CD1 4.14Å; F202-P207 WeakPolarHBondContact O-CD 3.13Å; F202-P207 WeakPolarHBondContact O-CG 3.16Å; F202-Y386 PolarHBondContact O-OH 2.79Å; F202-I397 HydrophobicContact CD1-CD1 3.75Å; F202-I397 HydrophobicContact CE1-CD1 4.05Å; F202-A508 HydrophobicContact CE2-CB 4.48Å; F202-L509 HydrophobicContact CZ-CB 4.17Å; F202-L509 HydrophobicContact CZ-CD1 3.97Å; F202-H512 HydrophobicContact CD2-CB 4.25Å; F202-H512 HydrophobicContact CE2-CB 3.66Å; F202-H512 HydrophobicContact CZ-CB 4.42Å
203	L	81.2	Confident	75.8	Confident	89 Å²	89	48.9 Å²	48.9	47%	0.466	24%	0.241	S	C	.	.	I	π-helix	trans	-94.4	-34.8	177.8	-78.2	69.5	0	0	0	113.3	N199 F201 Y383 Y386	N199-L203 WeakPolarHBondContact O-CB 3.4Å; N199-L203 WeakPolarHBondContact O-CD1 3.44Å; N199-L203 PolarHBondContact O-N 2.89Å; F201-L203 PolarHBondContact O-N 3.31Å; L203-Y383 PolarHBondContact O-OH 2.86Å; L203-Y386 WeakPolarHBondContact CD1-OH 3.41Å; L203-Y386 HydrophobicContact CG-CE1 4.2Å
204	L	82.5	Confident	77.5	Confident	101 Å²	101	44.7 Å²	44.7	53%	0.529	22%	0.221	S	C	.	.	I	π-helix	trans	-109.8	-42.6	-171.2	-170.3	66.4	0	0	0	114.2	M200 P208	M200-L204 HydrophobicContact CE-CD2 3.72Å; M200-L204 WeakPolarHBondContact O-CA 3.33Å; M200-L204 VanDerWaalsContact O-CB 3.26Å; M200-L204 WeakPolarHBondContact O-CB 3.31Å; M200-L204 PolarHBondContact O-N 3.46Å; L204-P208 WeakPolarHBondContact O-CD 3.41Å
205	L	84.2	Confident	79.3	Confident	19 Å²	19	43.8 Å²	43.8	10%	0.099	22%	0.216	C	C	.	.	I	π-helix	trans	-91.1	-40	-170.7	-59.2	176.3	0	0	0	113.5	F196 M200 F201 I209 C434 V438 F441	F196-L205 HydrophobicContact CE2-CD1 4.03Å; F196-L205 HydrophobicContact CZ-CD1 4.24Å; M200-L205 PolarHBondContact O-N 3.48Å; F201-L205 HydrophobicContact CD2-CB 4.23Å; F201-L205 HydrophobicContact CD2-CD1 4.42Å; F201-L205 PolarHBondContact O-N 2.66Å; F201-L205 VanDerWaalsContact O-N 3.1Å; L205-I209 WeakPolarHBondContact O-CD1 3.33Å; L205-I209 WeakPolarHBondContact O-CG1 3.48Å; L205-C434 WeakPolarHBondContact O-CB 3.39Å; L205-V438 HydrophobicContact CB-CG2 3.97Å; L205-V438 HydrophobicContact CD1-CG2 3.87Å; L205-V438 HydrophobicContact CG-CG2 4.48Å; L205-F441 HydrophobicContact CD1-CD2 4.35Å; L205-F441 HydrophobicContact CD1-CE2 4.11Å
206	L	84.8	Confident	80.5	Confident	1 Å²	1	39 Å²	39	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-76.6	-42.5	-176.6	178.3	154	0	0	0	113.6	F201 F202 I209 I210 I309 I397 I505	F201-L206 HydrophobicContact CD1-CB 4.2Å; F201-L206 HydrophobicContact CD1-CD1 4.27Å; F201-L206 HydrophobicContact CE1-CB 3.87Å; F201-L206 HydrophobicContact CE1-CD1 3.39Å; F201-L206 HydrophobicContact CE1-CG 4.24Å; F201-L206 HydrophobicContact CZ-CB 4.1Å; F201-L206 HydrophobicContact CZ-CD1 3.86Å; F201-L206 WeakPolarHBondContact O-CB 3.31Å; F201-L206 PolarHBondContact O-N 3.43Å; F202-L206 HydrophobicContact CD1-CD1 4.27Å; F202-L206 HydrophobicContact CE1-CD1 4.14Å; L206-I209 PolarHBondContact O-N 3.21Å; L206-I209 VanDerWaalsContact O-N 3.15Å; L206-I210 HydrophobicContact CD2-CB 4.5Å; L206-I210 HydrophobicContact CD2-CG1 3.64Å; L206-I210 HydrophobicContact CG-CG1 3.88Å; L206-I210 PolarHBondContact O-N 2.92Å; L206-I210 VanDerWaalsContact O-N 3.1Å; L206-I309 HydrophobicContact CD1-CD1 4.22Å; L206-I397 HydrophobicContact CD1-CD1 4.17Å; L206-I397 HydrophobicContact CD2-CB 4.23Å; L206-I397 HydrophobicContact CD2-CD1 3.68Å; L206-I397 HydrophobicContact CD2-CG1 3.59Å; L206-I397 HydrophobicContact CD2-CG2 3.73Å; L206-I505 HydrophobicContact CD1-CG1 4.4Å
207	P	89.8	Confident	81.1	Confident	4 Å²	4	38.2 Å²	38.2	3%	0.026	19%	0.193	C	C	.	.	H	α-helix	trans	-55.3	-42.1	-177	-30.8	39.4	0	0	0	115.6	F202 F211 Y383 Y386 I400	F202-P207 WeakPolarHBondContact O-CD 3.13Å; F202-P207 WeakPolarHBondContact O-CG 3.16Å; P207-F211 WeakPolarHBondContact O-CB 3.47Å; P207-F211 PolarHBondContact O-N 3.38Å; P207-Y383 HydrophobicContact CB-CD2 4.11Å; P207-Y383 HydrophobicContact CB-CE2 3.81Å; P207-Y383 HydrophobicContact CG-CE2 4.02Å; P207-Y386 HydrophobicContact CG-CD2 4.49Å; P207-Y386 HydrophobicContact CG-CE2 4.44Å; P207-I400 HydrophobicContact CB-CD1 3.61Å; P207-I400 HydrophobicContact CG-CD1 4.03Å
208	P	90.6	Very high	81	Confident	31 Å²	31	36 Å²	36	20%	0.201	19%	0.19	C	C	.	.	H	α-helix	trans	-66.7	-37.2	176.3	-21	34.2	0	0	0	113.8	L204 F211 E212 V430	L204-P208 WeakPolarHBondContact O-CD 3.41Å; P208-F211 PolarHBondContact O-N 3.39Å; P208-E212 PolarHBondContact O-N 2.88Å; P208-V430 HydrophobicContact CB-CG1 3.67Å; P208-V430 HydrophobicContact CG-CG1 4.1Å
209	I	88.3	Confident	80.9	Confident	21 Å²	21	35.3 Å²	35.3	11%	0.108	18%	0.183	C	C	.	.	H	α-helix	trans	-63.7	-48.6	178.9	-60	171.3	0	0	0	110.2	L205 L206 E212 S213 C434 E435	L205-I209 WeakPolarHBondContact O-CD1 3.33Å; L205-I209 WeakPolarHBondContact O-CG1 3.48Å; L206-I209 PolarHBondContact O-N 3.21Å; L206-I209 VanDerWaalsContact O-N 3.15Å; I209-E212 PolarHBondContact O-N 3Å; I209-S213 WeakPolarHBondContact O-CB 3.3Å; I209-S213 PolarHBondContact O-N 2.78Å; I209-S213 PolarHBondContact O-OG 2.76Å; I209-C434 HydrophobicContact CD1-CB 3.74Å; I209-C434 HydrophobicContact CG1-CB 3.59Å; I209-E435 HydrophobicContact CD1-CG 4.25Å; I209-E435 HydrophobicContact CG1-CG 4.39Å; I209-E435 HydrophobicContact CG2-CG 4.34Å
210	I	88.6	Confident	80.3	Confident	3 Å²	3	31.5 Å²	31.5	2%	0.015	17%	0.169	C	C	.	.	H	α-helix	trans	-69.4	-35.9	-179	-61.2	-59.9	0	0	0	111.3	L206 G214 I397 I400 L401 I505	L206-I210 HydrophobicContact CD2-CB 4.5Å; L206-I210 HydrophobicContact CD2-CG1 3.64Å; L206-I210 HydrophobicContact CG-CG1 3.88Å; L206-I210 PolarHBondContact O-N 2.92Å; L206-I210 VanDerWaalsContact O-N 3.1Å; I210-G214 PolarHBondContact O-N 3.26Å; I210-I397 HydrophobicContact CG1-CG2 4.28Å; I210-I397 HydrophobicContact CG2-CG2 4.42Å; I210-I400 HydrophobicContact CG2-CG2 4.27Å; I210-L401 HydrophobicContact CG2-CB 3.72Å; I210-L401 HydrophobicContact CG2-CD1 4.22Å; I210-L401 HydrophobicContact CG2-CG 4.39Å; I210-I505 HydrophobicContact CD1-CD1 4.36Å
211	F	91.2	Very high	79.9	Confident	4 Å²	4	30.4 Å²	30.4	2%	0.018	17%	0.165	C	C	.	.	H	α-helix	trans	-68.6	-43.7	175.1	-168.6	-94.1	0	0	0	112.5	P207 P208 S213 G214 Y215 A382 I400 G404 M407 M423 L427	P207-F211 WeakPolarHBondContact O-CB 3.47Å; P207-F211 PolarHBondContact O-N 3.38Å; P208-F211 PolarHBondContact O-N 3.39Å; F211-S213 VanDerWaalsContact C-N 3.35Å; F211-G214 PolarHBondContact O-N 2.76Å; F211-Y215 HydrophobicContact CE1-CD2 4.08Å; F211-Y215 HydrophobicContact CE1-CG 4.27Å; F211-Y215 HydrophobicContact CZ-CD2 4.17Å; F211-Y215 WeakPolarHBondContact O-CB 3.36Å; F211-Y215 PolarHBondContact O-N 3.41Å; F211-A382 HydrophobicContact CD1-CB 3.82Å; F211-A382 HydrophobicContact CD2-CB 3.81Å; F211-A382 HydrophobicContact CE1-CB 3.6Å; F211-A382 HydrophobicContact CE2-CB 3.59Å; F211-A382 HydrophobicContact CG-CB 3.92Å; F211-A382 HydrophobicContact CZ-CB 3.48Å; F211-A382 VanDerWaalsContact CZ-CB 3.48Å; F211-I400 HydrophobicContact CB-CG2 3.65Å; F211-I400 HydrophobicContact CD2-CG2 3.88Å; F211-I400 HydrophobicContact CG-CG2 4.27Å; F211-G404 VanDerWaalsContact CE2-CA 3.43Å; F211-M407 HydrophobicContact CE2-CE 4.39Å; F211-M407 HydrophobicContact CE2-SD 3.81Å; F211-M407 HydrophobicContact CZ-CB 4.39Å; F211-M407 HydrophobicContact CZ-CE 3.83Å; F211-M407 HydrophobicContact CZ-SD 3.81Å; F211-M423 HydrophobicContact CE1-CE 4Å; F211-L427 HydrophobicContact CD1-CD1 3.87Å; F211-L427 HydrophobicContact CD1-CD2 3.68Å; F211-L427 HydrophobicContact CD1-CG 4.43Å; F211-L427 HydrophobicContact CE1-CD1 3.73Å; F211-L427 HydrophobicContact CE1-CD2 4.1Å
212	E	89.1	Confident	79.6	Confident	25 Å²	25	30.7 Å²	30.7	12%	0.117	17%	0.166	C	C	.	.	H	α-helix	trans	-59.5	-48.7	174.1	-157.9	-80.9	-178.5	0	0	110.3	P208 I209 G214 Y215 S216 L427 R428 A431	P208-E212 PolarHBondContact O-N 2.88Å; I209-E212 PolarHBondContact O-N 3Å; E212-G214 VanDerWaalsContact C-N 3.28Å; E212-G214 PolarHBondContact O-N 2.87Å; E212-Y215 CarbonylContact O-C 3.6Å; E212-Y215 WeakPolarHBondContact O-CA 3.45Å; E212-Y215 PolarHBondContact O-N 3.19Å; E212-S216 WeakPolarHBondContact O-CB 3.29Å; E212-S216 PolarHBondContact O-N 3.46Å; E212-S216 PolarHBondContact O-OG 3.23Å; E212-S216 VanDerWaalsContact OE2-CB 3.3Å; E212-S216 WeakPolarHBondContact OE2-CB 3.44Å; E212-S216 PolarHBondContact OE2-OG 3.19Å; E212-L427 HydrophobicContact CB-CB 4.36Å; E212-L427 HydrophobicContact CG-CB 3.88Å; E212-R428 HydrophobicContact CG-CB 4.46Å; E212-R428 IonicContact OE1-NE 2.78Å; E212-R428 PolarHBondContact OE1-NE 3.38Å; E212-R428 IonicContact OE1-NH2 2.57Å; E212-A431 HydrophobicContact CB-CB 3.6Å; E212-A431 HydrophobicContact CG-CB 3.93Å
213	S	83.3	Confident	79.5	Confident	20 Å²	20	32.8 Å²	32.8	14%	0.14	18%	0.175	C	C	.	.	H	α-helix	trans	-58.3	-38.1	-179.2	-60.6	0	0	0	0	113.1	I209 F211 I302	I209-S213 WeakPolarHBondContact O-CB 3.3Å; I209-S213 PolarHBondContact O-N 2.78Å; I209-S213 PolarHBondContact O-OG 2.76Å; F211-S213 VanDerWaalsContact C-N 3.35Å; S213-I302 WeakPolarHBondContact O-CD1 3.33Å
214	G	86.2	Confident	79.1	Confident	0 Å²	0	33.8 Å²	33.8	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-71.7	-30.5	171.8	0	0	0	0	0	113.5	I210 F211 E212 L217 G404 I405	I210-G214 PolarHBondContact O-N 3.26Å; F211-G214 PolarHBondContact O-N 2.76Å; E212-G214 VanDerWaalsContact C-N 3.28Å; E212-G214 PolarHBondContact O-N 2.87Å; G214-L217 WeakPolarHBondContact O-CB 3.47Å; G214-G404 CarbonylContact O-C 3.57Å; G214-I405 VanDerWaalsContact O-CA 3.31Å; G214-I405 WeakPolarHBondContact O-CA 3.34Å; G214-I405 PolarHBondContact O-N 2.96Å
215	Y	87.4	Confident	78.9	Confident	10 Å²	10	30.2 Å²	30.2	4%	0.039	16%	0.159	C	C	.	.	H	α-helix	trans	-88.6	-32.9	-173.9	-166.2	-98.6	0	0	0	114	F211 E212 L217 M378 M407 S408 H412 M423 Q424 L427	F211-Y215 HydrophobicContact CE1-CD2 4.08Å; F211-Y215 HydrophobicContact CE1-CG 4.27Å; F211-Y215 HydrophobicContact CZ-CD2 4.17Å; F211-Y215 WeakPolarHBondContact O-CB 3.36Å; F211-Y215 PolarHBondContact O-N 3.41Å; E212-Y215 CarbonylContact O-C 3.6Å; E212-Y215 WeakPolarHBondContact O-CA 3.45Å; E212-Y215 PolarHBondContact O-N 3.19Å; Y215-L217 PolarHBondContact O-N 2.51Å; Y215-M378 HydrophobicContact CE2-CE 3.97Å; Y215-M407 HydrophobicContact CD2-CB 4.32Å; Y215-M407 HydrophobicContact CE2-CB 4.25Å; Y215-S408 VanDerWaalsContact O-CB 3.23Å; Y215-S408 WeakPolarHBondContact O-CB 3.33Å; Y215-S408 PolarHBondContact O-OG 2.89Å; Y215-H412 AromaticContact CE1-ND1 3.99Å; Y215-H412 AromaticContact CZ-ND1 3.59Å; Y215-H412 PolarHBondContact OH-ND1 2.91Å; Y215-M423 HydrophobicContact CE1-CG 3.96Å; Y215-Q424 HydrophobicContact CE1-CG 4.32Å; Y215-L427 HydrophobicContact CD1-CD1 3.47Å; Y215-L427 VanDerWaalsContact CD1-CD1 3.47Å; Y215-L427 HydrophobicContact CE1-CD1 3.87Å; Y215-L427 HydrophobicContact CG-CD1 3.85Å
216	S	78.7	Confident	78.7	Confident	28 Å²	28	32 Å²	32	20%	0.196	17%	0.168	C	C	.	.	S	Bend	trans	-82	3.7	177.8	64.6	0	0	0	0	113.9	E212 H218	E212-S216 WeakPolarHBondContact O-CB 3.29Å; E212-S216 PolarHBondContact O-N 3.46Å; E212-S216 PolarHBondContact O-OG 3.23Å; E212-S216 VanDerWaalsContact OE2-CB 3.3Å; E212-S216 WeakPolarHBondContact OE2-CB 3.44Å; E212-S216 PolarHBondContact OE2-OG 3.19Å; S216-H218 PolarHBondContact O-N 3.01Å; S216-H218 PolarHBondContact O-ND1 3.34Å; S216-H218 VanDerWaalsContact O-ND1 3.13Å
217	L	71	Confident	78.7	Confident	9 Å²	9	34.5 Å²	34.5	5%	0.047	19%	0.194	C	C	.	.			trans	-69	123	-174.5	-165.4	59.1	0	0	0	112.2	G214 Y215 K219 F222 F298 I302 I405	G214-L217 WeakPolarHBondContact O-CB 3.47Å; Y215-L217 PolarHBondContact O-N 2.51Å; L217-K219 PolarHBondContact O-N 3.4Å; L217-F222 HydrophobicContact CD1-CD2 3.64Å; L217-F222 HydrophobicContact CD1-CE2 3.9Å; L217-F222 HydrophobicContact CD1-CG 4.12Å; L217-F222 HydrophobicContact CD2-CD1 3.73Å; L217-F222 HydrophobicContact CD2-CD2 3.93Å; L217-F222 HydrophobicContact CD2-CE1 3.59Å; L217-F222 HydrophobicContact CD2-CE2 3.79Å; L217-F222 HydrophobicContact CD2-CG 3.9Å; L217-F222 HydrophobicContact CD2-CZ 3.63Å; L217-F222 HydrophobicContact CG-CB 4.31Å; L217-F222 HydrophobicContact CG-CD1 4.12Å; L217-F222 HydrophobicContact CG-CD2 3.86Å; L217-F222 HydrophobicContact CG-CE1 4.43Å; L217-F222 HydrophobicContact CG-CE2 4.19Å; L217-F222 HydrophobicContact CG-CG 3.82Å; L217-F222 HydrophobicContact CG-CZ 4.46Å; L217-F298 HydrophobicContact CD1-CD1 3.99Å; L217-F298 HydrophobicContact CD1-CE1 3.68Å; L217-F298 HydrophobicContact CD1-CZ 4.5Å; L217-I302 HydrophobicContact CD1-CD1 4.25Å; L217-I405 HydrophobicContact CD2-CD1 4.07Å; L217-I405 HydrophobicContact CD2-CG1 3.8Å; L217-I405 HydrophobicContact CD2-CG2 4.48Å
218	H	62.8	Low	78.6	Confident	134 Å²	134	34.9 Å²	34.9	62%	0.62	20%	0.196	S	C	*	.			trans	-72.8	91.6	-172.7	-71.4	46.9	0	0	0	112	S216 G220 F222	S216-H218 PolarHBondContact O-N 3.01Å; S216-H218 PolarHBondContact O-ND1 3.34Å; S216-H218 VanDerWaalsContact O-ND1 3.13Å; H218-G220 PolarHBondContact O-N 3Å; H218-F222 VanDerWaalsContact O-CB 3.24Å; H218-F222 WeakPolarHBondContact O-CB 3.47Å; H218-F222 PolarHBondContact O-N 3.15Å
219	K	63.3	Low	78.5	Confident	18 Å²	18	33.4 Å²	33.4	8%	0.078	19%	0.187	C	C	.	.	H	α-helix	trans	-46.5	-56	-164.2	-55.4	148.3	-163.5	158	0	113.6	L217 F222 F223 S408 E589	L217-K219 PolarHBondContact O-N 3.4Å; K219-F222 PolarHBondContact O-N 3.35Å; K219-F223 HydrophobicContact CB-CE2 4.48Å; K219-F223 VanDerWaalsContact O-CD2 3.23Å; K219-F223 WeakPolarHBondContact O-CD2 3.3Å; K219-F223 PolarHBondContact O-N 3.4Å; K219-F223 VanDerWaalsContact O-N 3.08Å; K219-S408 WeakPolarHBondContact CE-O 3.4Å; K219-S408 WeakPolarHBondContact CE-OG 3.33Å; K219-E589 IonicContact NZ-OE1 3.7Å; K219-E589 IonicContact NZ-OE2 2.75Å; K219-E589 PolarHBondContact NZ-OE2 3.01Å
220	G	60	Low	78.5	Confident	24 Å²	24	34.8 Å²	34.8	25%	0.247	20%	0.196	C	C	.	.	H	α-helix	trans	-59.6	-53.2	-170.2	0	0	0	0	0	113.8	H218 Q224	H218-G220 PolarHBondContact O-N 3Å; G220-Q224 WeakPolarHBondContact O-CG 3.45Å
221	N	64.3	Low	78.6	Confident	82 Å²	82	36.7 Å²	36.7	44%	0.439	21%	0.207	S	C	.	.	H	α-helix	trans	-73.4	-31.6	178.5	-69.6	-12.8	0	0	0	112	N225 M295	N221-N225 PolarHBondContact O-ND2 2.85Å; N221-N225 VanDerWaalsContact O-ND2 3.11Å; N221-M295 WeakPolarHBondContact O-CE 3.36Å
222	F	70.1	Confident	78.5	Confident	8 Å²	8	36.7 Å²	36.7	4%	0.035	21%	0.206	C	C	.	.	H	α-helix	trans	-61.6	-55.5	-179.5	-177.5	-101.1	0	0	0	112.2	L217 H218 K219 Q224 N225 I226 I229 M295	L217-F222 HydrophobicContact CD1-CD2 3.64Å; L217-F222 HydrophobicContact CD1-CE2 3.9Å; L217-F222 HydrophobicContact CD1-CG 4.12Å; L217-F222 HydrophobicContact CD2-CD1 3.73Å; L217-F222 HydrophobicContact CD2-CD2 3.93Å; L217-F222 HydrophobicContact CD2-CE1 3.59Å; L217-F222 HydrophobicContact CD2-CE2 3.79Å; L217-F222 HydrophobicContact CD2-CG 3.9Å; L217-F222 HydrophobicContact CD2-CZ 3.63Å; L217-F222 HydrophobicContact CG-CB 4.31Å; L217-F222 HydrophobicContact CG-CD1 4.12Å; L217-F222 HydrophobicContact CG-CD2 3.86Å; L217-F222 HydrophobicContact CG-CE1 4.43Å; L217-F222 HydrophobicContact CG-CE2 4.19Å; L217-F222 HydrophobicContact CG-CG 3.82Å; L217-F222 HydrophobicContact CG-CZ 4.46Å; H218-F222 VanDerWaalsContact O-CB 3.24Å; H218-F222 WeakPolarHBondContact O-CB 3.47Å; H218-F222 PolarHBondContact O-N 3.15Å; K219-F222 PolarHBondContact O-N 3.35Å; F222-Q224 VanDerWaalsContact C-N 3.27Å; F222-Q224 PolarHBondContact O-N 3.07Å; F222-N225 PolarHBondContact O-N 2.63Å; F222-I226 HydrophobicContact CD1-CD1 4.5Å; F222-I226 HydrophobicContact CE1-CD1 3.59Å; F222-I226 HydrophobicContact CE2-CD1 4.32Å; F222-I226 HydrophobicContact CZ-CD1 3.47Å; F222-I226 VanDerWaalsContact CZ-CD1 3.47Å; F222-I226 PolarHBondContact O-N 3.4Å; F222-I226 VanDerWaalsContact O-N 3.09Å; F222-I229 HydrophobicContact CD2-CD1 3.74Å; F222-I229 HydrophobicContact CE2-CD1 3.56Å; F222-I229 HydrophobicContact CE2-CG2 4.35Å; F222-M295 HydrophobicContact CD2-CE 4.17Å; F222-M295 VanDerWaalsContact O-CE 3.24Å; F222-M295 WeakPolarHBondContact O-CE 3.49Å
223	F	71.6	Confident	78.6	Confident	58 Å²	58	35.5 Å²	35.5	25%	0.254	20%	0.201	S	C	.	.	H	α-helix	trans	-67.9	-24.4	-176.4	-71.5	-65.3	0	0	0	113.7	K219 N225 I226 I405 H409 M604	K219-F223 HydrophobicContact CB-CE2 4.48Å; K219-F223 VanDerWaalsContact O-CD2 3.23Å; K219-F223 WeakPolarHBondContact O-CD2 3.3Å; K219-F223 PolarHBondContact O-N 3.4Å; K219-F223 VanDerWaalsContact O-N 3.08Å; F223-N225 PolarHBondContact O-N 3.15Å; F223-I226 VanDerWaalsContact O-CG2 3.27Å; F223-I226 WeakPolarHBondContact O-CG2 3.03Å; F223-I405 HydrophobicContact CZ-CG2 3.92Å; F223-H409 AromaticContact CE2-CD2 3.91Å; F223-M604 HydrophobicContact CB-CE 4.5Å
224	Q	73.7	Confident	78.9	Confident	109 Å²	109	35.6 Å²	35.6	51%	0.509	20%	0.2	S	C	.	.	H	α-helix	trans	-65.6	-34.3	174.4	-73.5	176.2	9.4	0	0	113.4	G220 F222	G220-Q224 WeakPolarHBondContact O-CG 3.45Å; F222-Q224 VanDerWaalsContact C-N 3.27Å; F222-Q224 PolarHBondContact O-N 3.07Å
225	N	77.4	Confident	79.2	Confident	27 Å²	27	39.3 Å²	39.3	14%	0.144	22%	0.219	C	C	.	.	S	Bend	trans	-116.3	16.7	-176.5	-45	-100.5	0	0	0	113	N221 F222 F223 G227 S228 I229 M295 R484	N221-N225 PolarHBondContact O-ND2 2.85Å; N221-N225 VanDerWaalsContact O-ND2 3.11Å; F222-N225 PolarHBondContact O-N 2.63Å; F223-N225 PolarHBondContact O-N 3.15Å; N225-G227 PolarHBondContact O-N 3.45Å; N225-G227 VanDerWaalsContact O-N 3.16Å; N225-S228 WeakPolarHBondContact O-CB 3.38Å; N225-S228 PolarHBondContact O-N 3.41Å; N225-I229 PolarHBondContact O-N 3.26Å; N225-M295 HydrophobicContact CB-CE 3.52Å; N225-M295 HydrophobicContact CB-SD 3.92Å; N225-R484 PolarHBondContact OD1-NE 2.89Å; N225-R484 PolarHBondContact OD1-NH2 2.93Å
226	I	81.8	Confident	79.4	Confident	57 Å²	57	38.9 Å²	38.9	29%	0.292	22%	0.218	S	C	.	.	H	α-helix	trans	-52.1	-38.1	-179.7	-173.9	53.5	0	0	0	113.1	F222 F223 S228 I229 T230	F222-I226 HydrophobicContact CD1-CD1 4.5Å; F222-I226 HydrophobicContact CE1-CD1 3.59Å; F222-I226 HydrophobicContact CE2-CD1 4.32Å; F222-I226 HydrophobicContact CZ-CD1 3.47Å; F222-I226 VanDerWaalsContact CZ-CD1 3.47Å; F222-I226 PolarHBondContact O-N 3.4Å; F222-I226 VanDerWaalsContact O-N 3.09Å; F223-I226 VanDerWaalsContact O-CG2 3.27Å; F223-I226 WeakPolarHBondContact O-CG2 3.03Å; I226-S228 VanDerWaalsContact C-N 3.29Å; I226-S228 PolarHBondContact O-N 3.38Å; I226-I229 PolarHBondContact O-N 2.97Å; I226-T230 WeakPolarHBondContact O-CB 3.41Å; I226-T230 PolarHBondContact O-N 3.04Å; I226-T230 PolarHBondContact O-OG1 3.05Å; I226-T230 VanDerWaalsContact O-OG1 3.1Å
227	G	84.4	Confident	80.1	Confident	53 Å²	53	37.6 Å²	37.6	55%	0.546	21%	0.209	S	C	.	.	H	α-helix	trans	-62.8	-32.3	176.6	0	0	0	0	0	113.7	N225 L231	N225-G227 PolarHBondContact O-N 3.45Å; N225-G227 VanDerWaalsContact O-N 3.16Å; G227-L231 WeakPolarHBondContact O-CB 3.27Å; G227-L231 PolarHBondContact O-N 3.49Å
228	S	87.1	Confident	81	Confident	11 Å²	11	38.1 Å²	38.1	8%	0.077	22%	0.215	C	C	.	.	H	α-helix	trans	-72.9	-44.3	173.6	-61.2	0	0	0	0	111.2	N225 I226 L231 F232	N225-S228 WeakPolarHBondContact O-CB 3.38Å; N225-S228 PolarHBondContact O-N 3.41Å; I226-S228 VanDerWaalsContact C-N 3.29Å; I226-S228 PolarHBondContact O-N 3.38Å; S228-L231 PolarHBondContact O-N 2.89Å; S228-F232 WeakPolarHBondContact O-CD2 3.39Å; S228-F232 PolarHBondContact O-N 3.42Å; S228-F232 VanDerWaalsContact O-N 3.13Å
229	I	88.3	Confident	82.5	Confident	0 Å²	0	34.1 Å²	34.1	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-61.8	-52.9	178.5	-72.9	-176.9	0	0	0	111.3	F222 N225 I226 L231 F232 A233 M295 L296 G299 L303	F222-I229 HydrophobicContact CD2-CD1 3.74Å; F222-I229 HydrophobicContact CE2-CD1 3.56Å; F222-I229 HydrophobicContact CE2-CG2 4.35Å; N225-I229 PolarHBondContact O-N 3.26Å; I226-I229 PolarHBondContact O-N 2.97Å; I229-L231 PolarHBondContact O-N 3.36Å; I229-F232 PolarHBondContact O-N 2.85Å; I229-F232 VanDerWaalsContact O-N 3.1Å; I229-A233 VanDerWaalsContact O-CB 3.29Å; I229-A233 WeakPolarHBondContact O-CB 3.33Å; I229-A233 PolarHBondContact O-N 3.38Å; I229-M295 HydrophobicContact CD1-CE 3.11Å; I229-M295 HydrophobicContact CD1-SD 3.82Å; I229-M295 HydrophobicContact CG1-CE 3.88Å; I229-M295 HydrophobicContact CG1-SD 4.43Å; I229-L296 HydrophobicContact CG1-CD2 4.11Å; I229-G299 VanDerWaalsContact CG2-C 3.43Å; I229-G299 VanDerWaalsContact CG2-O 3.28Å; I229-G299 WeakPolarHBondContact CG2-O 3.29Å; I229-L303 HydrophobicContact CG2-CD1 3.81Å; I229-L303 HydrophobicContact CG2-CG 4.36Å
230	T	87.9	Confident	83.9	Confident	50 Å²	50	33.3 Å²	33.3	31%	0.307	19%	0.194	S	C	.	.	H	α-helix	trans	-61.2	-31.1	-179.3	-56	0	0	0	0	111.5	I226 V234	I226-T230 WeakPolarHBondContact O-CB 3.41Å; I226-T230 PolarHBondContact O-N 3.04Å; I226-T230 PolarHBondContact O-OG1 3.05Å; I226-T230 VanDerWaalsContact O-OG1 3.1Å; T230-V234 HydrophobicContact CG2-CG2 3.82Å; T230-V234 VanDerWaalsContact O-CB 3.25Å; T230-V234 WeakPolarHBondContact O-CB 3.49Å; T230-V234 WeakPolarHBondContact O-CG2 3.41Å; T230-V234 PolarHBondContact O-N 3.2Å
231	L	91	Very high	85.4	Confident	44 Å²	44	32.3 Å²	32.3	23%	0.23	18%	0.183	C	C	.	.	I	π-helix	trans	-65.1	-50.3	172.7	-167.6	76	0	0	0	111.7	G227 S228 I229 I235 G236 L476 L480	G227-L231 WeakPolarHBondContact O-CB 3.27Å; G227-L231 PolarHBondContact O-N 3.49Å; S228-L231 PolarHBondContact O-N 2.89Å; I229-L231 PolarHBondContact O-N 3.36Å; L231-I235 HydrophobicContact CD1-CB 4.2Å; L231-I235 HydrophobicContact CD1-CG1 3.82Å; L231-I235 WeakPolarHBondContact O-CA 3.18Å; L231-I235 VanDerWaalsContact O-CB 3.29Å; L231-I235 WeakPolarHBondContact O-CB 3.12Å; L231-I235 PolarHBondContact O-N 3.22Å; L231-G236 PolarHBondContact O-N 3.4Å; L231-G236 VanDerWaalsContact O-N 3.08Å; L231-L476 HydrophobicContact CD2-CB 4.47Å; L231-L476 HydrophobicContact CD2-CD2 4.07Å; L231-L476 HydrophobicContact CG-CD2 4.2Å; L231-L480 HydrophobicContact CD2-CD1 3.94Å; L231-L480 HydrophobicContact CD2-CD2 3.72Å; L231-L480 HydrophobicContact CD2-CG 3.64Å
232	F	90.3	Very high	86.7	Confident	3 Å²	3	33.4 Å²	33.4	1%	0.013	18%	0.184	C	C	.	.	I	π-helix	trans	-65	-43	177	-67.4	-64.7	0	0	0	112.1	S228 I229 G236 T237 L296 E300 I473 L476 S477 L480 I488 M496	S228-F232 WeakPolarHBondContact O-CD2 3.39Å; S228-F232 PolarHBondContact O-N 3.42Å; S228-F232 VanDerWaalsContact O-N 3.13Å; I229-F232 PolarHBondContact O-N 2.85Å; I229-F232 VanDerWaalsContact O-N 3.1Å; F232-G236 CarbonylContact O-C 3.57Å; F232-G236 WeakPolarHBondContact O-CA 3.49Å; F232-G236 PolarHBondContact O-N 3.4Å; F232-T237 PolarHBondContact O-N 2.84Å; F232-L296 HydrophobicContact CE2-CD2 4.47Å; F232-E300 HydrophobicContact CB-CG 3.84Å; F232-I473 HydrophobicContact CD1-CD1 4.05Å; F232-I473 HydrophobicContact CE1-CD1 4.18Å; F232-L476 HydrophobicContact CD1-CB 3.93Å; F232-L476 HydrophobicContact CD1-CD1 4.11Å; F232-L476 HydrophobicContact CE1-CB 3.71Å; F232-S477 WeakPolarHBondContact CZ-OG 3.35Å; F232-L480 HydrophobicContact CD2-CD1 4.09Å; F232-L480 HydrophobicContact CE1-CD1 4.22Å; F232-L480 HydrophobicContact CE2-CD1 3.43Å; F232-L480 VanDerWaalsContact CE2-CD1 3.43Å; F232-L480 HydrophobicContact CZ-CD1 3.51Å; F232-I488 HydrophobicContact CE2-CD1 4.19Å; F232-I488 HydrophobicContact CZ-CD1 4.03Å; F232-M496 HydrophobicContact CZ-CE 4.26Å
233	A	90.2	Very high	87.9	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	19%	0.192	C	C	.	.	I	π-helix	trans	-77.6	-20.2	-174.7	0	0	0	0	0	115.4	I229 T237 L303	I229-A233 VanDerWaalsContact O-CB 3.29Å; I229-A233 WeakPolarHBondContact O-CB 3.33Å; I229-A233 PolarHBondContact O-N 3.38Å; A233-T237 WeakPolarHBondContact O-CB 3.47Å; A233-T237 WeakPolarHBondContact O-CG2 3.18Å; A233-T237 PolarHBondContact O-OG1 2.81Å; A233-L303 HydrophobicContact CB-CB 3.44Å; A233-L303 VanDerWaalsContact CB-CB 3.44Å; A233-L303 HydrophobicContact CB-CD1 4.29Å; A233-L303 HydrophobicContact CB-CG 4.47Å
234	V	90.5	Very high	88.9	Confident	22 Å²	22	32.1 Å²	32.1	13%	0.133	18%	0.18	C	C	.	.	I	π-helix	trans	-109.4	-49.1	176.6	-175.6	0	0	0	0	111.8	T230 T237 A238 V307 F340 F344	T230-V234 HydrophobicContact CG2-CG2 3.82Å; T230-V234 VanDerWaalsContact O-CB 3.25Å; T230-V234 WeakPolarHBondContact O-CB 3.49Å; T230-V234 WeakPolarHBondContact O-CG2 3.41Å; T230-V234 PolarHBondContact O-N 3.2Å; V234-T237 PolarHBondContact O-OG1 3.11Å; V234-T237 VanDerWaalsContact O-OG1 3.14Å; V234-A238 VanDerWaalsContact O-CB 3.32Å; V234-A238 WeakPolarHBondContact O-CB 3.27Å; V234-A238 PolarHBondContact O-N 3.01Å; V234-V307 HydrophobicContact CG2-CG2 4.08Å; V234-F340 HydrophobicContact CG1-CE1 4.22Å; V234-F340 HydrophobicContact CG1-CZ 4.25Å; V234-F344 HydrophobicContact CG2-CE2 3.76Å; V234-F344 HydrophobicContact CG2-CZ 3.87Å
235	I	91.7	Very high	89.8	Confident	78 Å²	78	26.9 Å²	26.9	40%	0.4	16%	0.156	S	C	.	.	I	π-helix	trans	-84.3	-40.8	-178.2	-53.5	-56.1	0	0	0	110.5	L231 T237 A238 I239 L476	L231-I235 HydrophobicContact CD1-CB 4.2Å; L231-I235 HydrophobicContact CD1-CG1 3.82Å; L231-I235 WeakPolarHBondContact O-CA 3.18Å; L231-I235 VanDerWaalsContact O-CB 3.29Å; L231-I235 WeakPolarHBondContact O-CB 3.12Å; L231-I235 PolarHBondContact O-N 3.22Å; I235-T237 VanDerWaalsContact C-N 3.34Å; I235-T237 PolarHBondContact O-N 3.23Å; I235-A238 PolarHBondContact O-N 2.68Å; I235-I239 HydrophobicContact CG2-CD1 3.83Å; I235-I239 HydrophobicContact CG2-CG1 4.42Å; I235-I239 WeakPolarHBondContact O-CB 3.45Å; I235-I239 WeakPolarHBondContact O-CG1 3.36Å; I235-I239 PolarHBondContact O-N 3.44Å; I235-L476 HydrophobicContact CG2-CD2 4.2Å
236	G	91.8	Very high	90.5	Very high	1 Å²	1	26 Å²	26	1%	0.01	15%	0.153	C	C	.	.	I	π-helix	trans	-66.8	-35	178.1	0	0	0	0	0	113.4	L231 F232 S240 N472 L476	L231-G236 PolarHBondContact O-N 3.4Å; L231-G236 VanDerWaalsContact O-N 3.08Å; F232-G236 CarbonylContact O-C 3.57Å; F232-G236 WeakPolarHBondContact O-CA 3.49Å; F232-G236 PolarHBondContact O-N 3.4Å; G236-S240 WeakPolarHBondContact O-CB 3.36Å; G236-S240 PolarHBondContact O-N 3.04Å; G236-N472 WeakPolarHBondContact O-CB 3.17Å; G236-N472 PolarHBondContact O-ND2 3.29Å; G236-L476 VanDerWaalsContact CA-CD1 3.41Å
237	T	92.3	Very high	91	Very high	1 Å²	1	23.9 Å²	23.9	1%	0.006	15%	0.145	C	C	.	.	H	α-helix	trans	-71.8	-43.9	176.8	55.9	0	0	0	0	111.5	F232 A233 V234 I235 I239 S240 A241 N304 V307	F232-T237 PolarHBondContact O-N 2.84Å; A233-T237 WeakPolarHBondContact O-CB 3.47Å; A233-T237 WeakPolarHBondContact O-CG2 3.18Å; A233-T237 PolarHBondContact O-OG1 2.81Å; V234-T237 PolarHBondContact O-OG1 3.11Å; V234-T237 VanDerWaalsContact O-OG1 3.14Å; I235-T237 VanDerWaalsContact C-N 3.34Å; I235-T237 PolarHBondContact O-N 3.23Å; T237-I239 PolarHBondContact O-N 3.15Å; T237-S240 WeakPolarHBondContact O-CB 3.34Å; T237-S240 PolarHBondContact O-N 3.49Å; T237-A241 WeakPolarHBondContact O-CB 3.42Å; T237-A241 PolarHBondContact O-N 3.48Å; T237-N304 HydrophobicContact CG2-CB 3.67Å; T237-N304 WeakPolarHBondContact CG2-OD1 3.42Å; T237-V307 WeakPolarHBondContact OG1-CG1 3.37Å
238	A	91.8	Very high	91.3	Very high	21 Å²	21	21.4 Å²	21.4	17%	0.174	12%	0.119	C	C	.	.	H	α-helix	trans	-58.5	-45.4	170.5	0	0	0	0	0	112	V234 I235 S240 A241 F242	V234-A238 VanDerWaalsContact O-CB 3.32Å; V234-A238 WeakPolarHBondContact O-CB 3.27Å; V234-A238 PolarHBondContact O-N 3.01Å; I235-A238 PolarHBondContact O-N 2.68Å; A238-S240 PolarHBondContact O-N 2.96Å; A238-A241 PolarHBondContact O-N 3.3Å; A238-F242 HydrophobicContact CB-CD2 4.44Å; A238-F242 HydrophobicContact CB-CE2 4.36Å; A238-F242 WeakPolarHBondContact O-CB 3.45Å; A238-F242 WeakPolarHBondContact O-CD2 3.44Å; A238-F242 PolarHBondContact O-N 3.34Å
239	I	93.2	Very high	91.5	Very high	50 Å²	50	23.8 Å²	23.8	26%	0.256	13%	0.127	S	C	.	.	H	α-helix	trans	-59.7	-45.9	175.5	-73.2	168.6	0	0	0	111.2	I235 T237 A241 F242 I243 I471 N472 L476	I235-I239 HydrophobicContact CG2-CD1 3.83Å; I235-I239 HydrophobicContact CG2-CG1 4.42Å; I235-I239 WeakPolarHBondContact O-CB 3.45Å; I235-I239 WeakPolarHBondContact O-CG1 3.36Å; I235-I239 PolarHBondContact O-N 3.44Å; T237-I239 PolarHBondContact O-N 3.15Å; I239-A241 PolarHBondContact O-N 3.07Å; I239-F242 PolarHBondContact O-N 3.11Å; I239-I243 HydrophobicContact CG2-CD1 3.62Å; I239-I243 WeakPolarHBondContact O-CB 3.19Å; I239-I243 WeakPolarHBondContact O-CD1 3.24Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.24Å; I239-I243 PolarHBondContact O-N 3.23Å; I239-I471 HydrophobicContact CG2-CG2 4.27Å; I239-N472 HydrophobicContact CB-CB 4.23Å; I239-N472 HydrophobicContact CG2-CB 3.94Å; I239-L476 HydrophobicContact CD1-CD1 4.47Å; I239-L476 HydrophobicContact CD1-CD2 4.42Å
240	S	92.6	Very high	91.7	Very high	1 Å²	1	30.6 Å²	30.6	1%	0.007	16%	0.157	C	C	.	.	H	α-helix	trans	-57.2	-48.1	174.4	174	0	0	0	0	111.3	G236 T237 A238 I243 V244 S273	G236-S240 WeakPolarHBondContact O-CB 3.36Å; G236-S240 PolarHBondContact O-N 3.04Å; T237-S240 WeakPolarHBondContact O-CB 3.34Å; T237-S240 PolarHBondContact O-N 3.49Å; A238-S240 PolarHBondContact O-N 2.96Å; S240-I243 PolarHBondContact O-N 3.27Å; S240-V244 WeakPolarHBondContact O-CG2 3.23Å; S240-V244 PolarHBondContact O-N 3.09Å; S240-S273 WeakPolarHBondContact CB-OG 3.16Å; S240-S273 PolarHBondContact OG-OG 2.86Å
241	A	92.4	Very high	91.8	Very high	2 Å²	2	29.9 Å²	29.9	2%	0.017	15%	0.151	C	C	.	.	H	α-helix	trans	-65.7	-40.2	-179.1	0	0	0	0	0	113	T237 A238 I239 G245 G269 S273 L311	T237-A241 WeakPolarHBondContact O-CB 3.42Å; T237-A241 PolarHBondContact O-N 3.48Å; A238-A241 PolarHBondContact O-N 3.3Å; I239-A241 PolarHBondContact O-N 3.07Å; A241-G245 PolarHBondContact O-N 3.19Å; A241-G269 WeakPolarHBondContact CA-O 3.47Å; A241-G269 WeakPolarHBondContact CB-O 3.43Å; A241-S273 WeakPolarHBondContact CA-OG 3.12Å; A241-S273 PolarHBondContact N-OG 3.14Å; A241-S273 VanDerWaalsContact N-OG 3.13Å; A241-L311 HydrophobicContact CB-CD2 3.58Å
242	F	91.9	Very high	91.6	Very high	105 Å²	105	27.9 Å²	27.9	46%	0.461	14%	0.141	S	C	.	.	H	α-helix	trans	-65.7	-37.7	175.3	-79.3	-60.1	0	0	0	112.4	A238 I239 G246 F266 F333	A238-F242 HydrophobicContact CB-CD2 4.44Å; A238-F242 HydrophobicContact CB-CE2 4.36Å; A238-F242 WeakPolarHBondContact O-CB 3.45Å; A238-F242 WeakPolarHBondContact O-CD2 3.44Å; A238-F242 PolarHBondContact O-N 3.34Å; I239-F242 PolarHBondContact O-N 3.11Å; F242-G246 VanDerWaalsContact O-CA 3.32Å; F242-G246 WeakPolarHBondContact O-CA 3.21Å; F242-G246 PolarHBondContact O-N 2.91Å; F242-F266 HydrophobicContact CD1-CD1 4.21Å; F242-F266 AromaticContact CD1-CE1 3.74Å; F242-F266 HydrophobicContact CD1-CE1 3.74Å; F242-F266 HydrophobicContact CD1-CZ 4.34Å; F242-F266 HydrophobicContact CE1-CE1 4.44Å; F242-F333 AromaticContact CZ-CE2 3.98Å; F242-F333 HydrophobicContact CZ-CE2 3.98Å
243	I	94.4	Very high	91.5	Very high	39 Å²	39	32 Å²	32	20%	0.2	16%	0.161	C	C	.	.	H	α-helix	trans	-73.8	-45.1	179.7	-68.6	166.3	0	0	0	111.4	I239 S240 G247 I471	I239-I243 HydrophobicContact CG2-CD1 3.62Å; I239-I243 WeakPolarHBondContact O-CB 3.19Å; I239-I243 WeakPolarHBondContact O-CD1 3.24Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.24Å; I239-I243 PolarHBondContact O-N 3.23Å; S240-I243 PolarHBondContact O-N 3.27Å; I243-G247 WeakPolarHBondContact O-CA 3.42Å; I243-G247 PolarHBondContact O-N 3.22Å; I243-I471 HydrophobicContact CD1-CB 3.57Å; I243-I471 HydrophobicContact CD1-CD1 4Å; I243-I471 HydrophobicContact CD1-CG1 4.38Å; I243-I471 HydrophobicContact CD1-CG2 3.4Å
244	V	93.4	Very high	91.4	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-69	-50.7	178.8	178.2	0	0	0	0	110.7	S240 G247 I248 F268 I272 L464 V465	S240-V244 WeakPolarHBondContact O-CG2 3.23Å; S240-V244 PolarHBondContact O-N 3.09Å; V244-G247 PolarHBondContact O-N 3.48Å; V244-I248 HydrophobicContact CG1-CD1 3.8Å; V244-I248 VanDerWaalsContact O-CG1 3.29Å; V244-I248 WeakPolarHBondContact O-CG1 3.46Å; V244-I248 PolarHBondContact O-N 3.16Å; V244-F268 HydrophobicContact CG1-CD1 4.38Å; V244-F268 HydrophobicContact CG1-CE1 4.44Å; V244-I272 HydrophobicContact CG1-CG2 3.85Å; V244-L464 HydrophobicContact CG2-CB 4.41Å; V244-V465 HydrophobicContact CG1-CG2 4.32Å; V244-V465 HydrophobicContact CG2-CG2 4.07Å
245	G	91.8	Very high	91.1	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-68.5	-41.2	-178.9	0	0	0	0	0	113.3	A241 Y249 S265	A241-G245 PolarHBondContact O-N 3.19Å; G245-Y249 WeakPolarHBondContact O-CB 3.5Å; G245-Y249 PolarHBondContact O-N 2.96Å; G245-S265 WeakPolarHBondContact CA-O 3.2Å; G245-S265 VanDerWaalsContact O-CB 3.29Å; G245-S265 WeakPolarHBondContact O-CB 3.49Å
246	G	91.3	Very high	90.7	Very high	9 Å²	9	40.3 Å²	40.3	9%	0.093	22%	0.216	C	C	.	.	H	α-helix	trans	-64.7	-42.3	173.4	0	0	0	0	0	111.9	F242 Y249 F250 F266	F242-G246 VanDerWaalsContact O-CA 3.32Å; F242-G246 WeakPolarHBondContact O-CA 3.21Å; F242-G246 PolarHBondContact O-N 2.91Å; G246-Y249 PolarHBondContact O-N 2.9Å; G246-F250 WeakPolarHBondContact O-CD2 3.19Å; G246-F250 PolarHBondContact O-N 3.16Å; G246-F266 VanDerWaalsContact N-CE1 3.33Å
247	G	92.4	Very high	90.3	Very high	12 Å²	12	40.9 Å²	40.9	12%	0.124	22%	0.219	C	C	.	.	H	α-helix	trans	-58.9	-49.7	175.1	0	0	0	0	0	112.6	I243 V244 Y249 F250 L251	I243-G247 WeakPolarHBondContact O-CA 3.42Å; I243-G247 PolarHBondContact O-N 3.22Å; V244-G247 PolarHBondContact O-N 3.48Å; G247-Y249 VanDerWaalsContact C-N 3.34Å; G247-Y249 PolarHBondContact O-N 3.29Å; G247-F250 PolarHBondContact O-N 2.94Å; G247-L251 WeakPolarHBondContact O-CB 3.45Å; G247-L251 VanDerWaalsContact O-CD1 3.24Å; G247-L251 WeakPolarHBondContact O-CD1 3.37Å; G247-L251 PolarHBondContact O-N 2.98Å
248	I	91.8	Very high	89.8	Confident	0 Å²	0	44.8 Å²	44.8	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-59.5	-45.2	176.9	-71	164.7	0	0	0	110.9	V244 F250 L251 G252 I257 M260 F268 F457 C461 L464	V244-I248 HydrophobicContact CG1-CD1 3.8Å; V244-I248 VanDerWaalsContact O-CG1 3.29Å; V244-I248 WeakPolarHBondContact O-CG1 3.46Å; V244-I248 PolarHBondContact O-N 3.16Å; I248-F250 PolarHBondContact O-N 2.88Å; I248-L251 PolarHBondContact O-N 3.29Å; I248-G252 PolarHBondContact O-N 2.84Å; I248-I257 HydrophobicContact CB-CD1 4.36Å; I248-I257 HydrophobicContact CG1-CD1 4.42Å; I248-I257 HydrophobicContact CG2-CD1 4.1Å; I248-M260 HydrophobicContact CG2-CB 4.49Å; I248-M260 HydrophobicContact CG2-CG 4.35Å; I248-M260 HydrophobicContact CG2-SD 4.24Å; I248-F268 HydrophobicContact CD1-CD1 3.3Å; I248-F268 HydrophobicContact CD1-CE1 3.63Å; I248-F268 HydrophobicContact CD1-CG 4.37Å; I248-F457 HydrophobicContact CG2-CE2 3.94Å; I248-F457 HydrophobicContact CG2-CZ 4.37Å; I248-C461 VanDerWaalsContact CD1-SG 3.55Å; I248-L464 HydrophobicContact CG1-CD1 3.91Å
249	Y	90.8	Very high	89.4	Confident	62 Å²	62	49.5 Å²	49.5	24%	0.243	25%	0.251	C	S	.	.	H	α-helix	trans	-60.8	-45.9	177.5	-179.6	-104.8	0	0	0	112.5	G245 G246 G247 G252 Q253 M262	G245-Y249 WeakPolarHBondContact O-CB 3.5Å; G245-Y249 PolarHBondContact O-N 2.96Å; G246-Y249 PolarHBondContact O-N 2.9Å; G247-Y249 VanDerWaalsContact C-N 3.34Å; G247-Y249 PolarHBondContact O-N 3.29Å; Y249-G252 PolarHBondContact O-N 3.02Å; Y249-Q253 HydrophobicContact CE1-CG 4.2Å; Y249-Q253 HydrophobicContact CE2-CG 4.19Å; Y249-Q253 VanDerWaalsContact O-CG 3.29Å; Y249-Q253 WeakPolarHBondContact O-CG 3.4Å; Y249-Q253 PolarHBondContact O-N 3.1Å; Y249-Q253 PolarHBondContact OH-NE2 2.87Å; Y249-M262 HydrophobicContact CD2-CB 4.04Å; Y249-M262 HydrophobicContact CE2-CB 3.9Å
250	F	91.9	Very high	88.8	Confident	143 Å²	143	47.6 Å²	47.6	63%	0.627	24%	0.241	S	C	*	.	H	α-helix	trans	-68	-40.9	178.6	-73	-57.8	0	0	0	112.9	G246 G247 I248 G252 Q253 A254	G246-F250 WeakPolarHBondContact O-CD2 3.19Å; G246-F250 PolarHBondContact O-N 3.16Å; G247-F250 PolarHBondContact O-N 2.94Å; I248-F250 PolarHBondContact O-N 2.88Å; F250-G252 VanDerWaalsContact C-N 3.33Å; F250-G252 PolarHBondContact O-N 3.48Å; F250-Q253 PolarHBondContact O-N 2.9Å; F250-A254 WeakPolarHBondContact O-CB 3.42Å; F250-A254 PolarHBondContact O-N 3.26Å
251	L	89.9	Confident	88.4	Confident	34 Å²	34	50.2 Å²	50.2	18%	0.178	26%	0.257	C	S	.	.	H	α-helix	trans	-67.3	-33.9	176.6	-88.9	68.4	0	0	0	112.1	G247 I248 A254 D255 V256 I257 W460	G247-L251 WeakPolarHBondContact O-CB 3.45Å; G247-L251 VanDerWaalsContact O-CD1 3.24Å; G247-L251 WeakPolarHBondContact O-CD1 3.37Å; G247-L251 PolarHBondContact O-N 2.98Å; I248-L251 PolarHBondContact O-N 3.29Å; L251-A254 CarbonylContact O-C 3.59Å; L251-A254 PolarHBondContact O-N 3.14Å; L251-D255 PolarHBondContact O-N 3.39Å; L251-V256 PolarHBondContact O-N 3.3Å; L251-V256 VanDerWaalsContact O-N 3.08Å; L251-I257 HydrophobicContact CB-CD1 3.66Å; L251-I257 HydrophobicContact CB-CG1 3.83Å; L251-I257 HydrophobicContact CB-CG2 4.41Å; L251-I257 HydrophobicContact CD2-CG2 4.36Å; L251-W460 HydrophobicContact CD2-CB 3.78Å; L251-W460 HydrophobicContact CD2-CD2 3.37Å; L251-W460 HydrophobicContact CD2-CE3 3.62Å; L251-W460 HydrophobicContact CD2-CG 3.45Å; L251-W460 VanDerWaalsContact CD2-CG 3.45Å; L251-W460 HydrophobicContact CD2-CZ3 4.31Å
252	G	87.9	Confident	87.9	Confident	2 Å²	2	54.5 Å²	54.5	2%	0.021	28%	0.278	C	S	.	.	H	α-helix	trans	-75.2	-19.6	174.2	0	0	0	0	0	114.4	I248 Y249 F250	I248-G252 PolarHBondContact O-N 2.84Å; Y249-G252 PolarHBondContact O-N 3.02Å; F250-G252 VanDerWaalsContact C-N 3.33Å; F250-G252 PolarHBondContact O-N 3.48Å
253	Q	88.1	Confident	87.5	Confident	91 Å²	91	50.9 Å²	50.9	43%	0.425	26%	0.264	S	S	.	.	H	α-helix	trans	-85.9	-22.9	167.7	-66.9	-75.7	24.6	0	0	112.4	Y249 F250 D255	Y249-Q253 HydrophobicContact CE1-CG 4.2Å; Y249-Q253 HydrophobicContact CE2-CG 4.19Å; Y249-Q253 VanDerWaalsContact O-CG 3.29Å; Y249-Q253 WeakPolarHBondContact O-CG 3.4Å; Y249-Q253 PolarHBondContact O-N 3.1Å; Y249-Q253 PolarHBondContact OH-NE2 2.87Å; F250-Q253 PolarHBondContact O-N 2.9Å; Q253-D255 VanDerWaalsContact C-N 3.29Å
254	A	88.1	Confident	87.1	Confident	65 Å²	65	49.5 Å²	49.5	54%	0.537	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.7	4.3	172.5	0	0	0	0	0	114	F250 L251 V256	F250-A254 WeakPolarHBondContact O-CB 3.42Å; F250-A254 PolarHBondContact O-N 3.26Å; L251-A254 CarbonylContact O-C 3.59Å; L251-A254 PolarHBondContact O-N 3.14Å; A254-V256 HydrophobicContact CB-CG2 4.02Å; A254-V256 PolarHBondContact O-N 3.45Å
255	D	83.7	Confident	86.9	Confident	144 Å²	144	49.5 Å²	49.5	77%	0.77	26%	0.257	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.1	22.8	-180	-135.6	39.7	0	0	0	114.4	L251 Q253	L251-D255 PolarHBondContact O-N 3.39Å; Q253-D255 VanDerWaalsContact C-N 3.29Å
256	V	83.1	Confident	86.8	Confident	65 Å²	65	51 Å²	51	39%	0.394	26%	0.264	S	S	.	.	S	Bend	trans	-87	-28.2	179.9	-179.5	0	0	0	0	111.9	L251 A254 S456	L251-V256 PolarHBondContact O-N 3.3Å; L251-V256 VanDerWaalsContact O-N 3.08Å; A254-V256 HydrophobicContact CB-CG2 4.02Å; A254-V256 PolarHBondContact O-N 3.45Å; V256-S456 PolarHBondContact O-OG 2.9Å
257	I	84.6	Confident	86.7	Confident	12 Å²	12	50.6 Å²	50.6	6%	0.062	26%	0.259	C	S	.	.	S	Bend	trans	-140	167.5	179.9	72.8	179.7	0	0	0	110.1	I248 L251 K259 F457 W460	I248-I257 HydrophobicContact CB-CD1 4.36Å; I248-I257 HydrophobicContact CG1-CD1 4.42Å; I248-I257 HydrophobicContact CG2-CD1 4.1Å; L251-I257 HydrophobicContact CB-CD1 3.66Å; L251-I257 HydrophobicContact CB-CG1 3.83Å; L251-I257 HydrophobicContact CB-CG2 4.41Å; L251-I257 HydrophobicContact CD2-CG2 4.36Å; I257-K259 PolarHBondContact O-N 3.45Å; I257-F457 HydrophobicContact CB-CB 4.3Å; I257-F457 HydrophobicContact CB-CD2 3.99Å; I257-F457 HydrophobicContact CD1-CD2 3.82Å; I257-F457 HydrophobicContact CD1-CE2 4.12Å; I257-F457 HydrophobicContact CG1-CD2 4.06Å; I257-W460 HydrophobicContact CG2-CB 4.1Å; I257-W460 HydrophobicContact CG2-CG 4.09Å
258	Y	81.8	Confident	86.6	Confident	83 Å²	83	50 Å²	50	33%	0.325	25%	0.253	S	S	.	.			trans	-50.8	130.2	178.2	-174.9	-85.7	0	0	0	112.9	M260 K520 L523	Y258-M260 HydrophobicContact CD1-CG 4.03Å; Y258-M260 PolarHBondContact O-N 3.09Å; Y258-K520 HydrophobicContact CE1-CG 4.36Å; Y258-L523 HydrophobicContact CD1-CD2 3.62Å; Y258-L523 HydrophobicContact CD2-CD2 4.17Å; Y258-L523 HydrophobicContact CE1-CD2 4.25Å; Y258-L523 HydrophobicContact CG-CD2 3.57Å
259	K	82.5	Confident	86.6	Confident	120 Å²	120	50 Å²	50	52%	0.522	25%	0.253	S	S	.	.			trans	-76.6	103.3	-172.6	-173.2	164.9	-169	147	0	112.6	I257	I257-K259 PolarHBondContact O-N 3.45Å
260	M	80	Confident	86.6	Confident	10 Å²	10	47.2 Å²	47.2	5%	0.049	24%	0.243	C	C	.	.			trans	-95.8	157.8	177.4	-59.1	-149.8	76.8	0	0	112.2	I248 Y258 D264 S265 F457 I524	I248-M260 HydrophobicContact CG2-CB 4.49Å; I248-M260 HydrophobicContact CG2-CG 4.35Å; I248-M260 HydrophobicContact CG2-SD 4.24Å; Y258-M260 HydrophobicContact CD1-CG 4.03Å; Y258-M260 PolarHBondContact O-N 3.09Å; M260-D264 HydrophobicContact CB-CB 4.38Å; M260-D264 HydrophobicContact CE-CB 3.5Å; M260-S265 WeakPolarHBondContact CB-OG 3.3Å; M260-F457 HydrophobicContact CG-CE2 4.16Å; M260-F457 HydrophobicContact SD-CE2 3.78Å; M260-F457 HydrophobicContact SD-CZ 3.69Å; M260-I524 HydrophobicContact CE-CD1 3.39Å; M260-I524 HydrophobicContact CE-CG1 4.06Å; M260-I524 HydrophobicContact SD-CD1 4.21Å; M260-I524 HydrophobicContact SD-CG1 4.48Å
261	T	84.5	Confident	86.5	Confident	57 Å²	57	40.4 Å²	40.4	35%	0.35	21%	0.213	S	C	.	.			trans	-71.8	163.2	169.4	83.7	0	0	0	0	110.4	T263 D264 S265	T261-T263 PolarHBondContact O-N 3.29Å; T261-T263 WeakPolarHBondContact OG1-CB 3.29Å; T261-T263 PolarHBondContact OG1-N 3.11Å; T261-D264 WeakPolarHBondContact CG2-OD2 3.34Å; T261-D264 PolarHBondContact N-OD2 3.06Å; T261-D264 PolarHBondContact O-N 3.08Å; T261-D264 PolarHBondContact OG1-N 3.02Å; T261-D264 PolarHBondContact OG1-OD1 2.74Å; T261-D264 PolarHBondContact OG1-OD2 3.34Å; T261-S265 WeakPolarHBondContact O-CB 3.44Å; T261-S265 PolarHBondContact O-N 3.27Å; T261-S265 PolarHBondContact O-OG 2.86Å
262	M	82.9	Confident	86.6	Confident	91 Å²	91	38.8 Å²	38.8	45%	0.448	21%	0.205	S	C	.	.	H	α-helix	trans	-57.2	-40.7	172.5	-169.5	175.4	179.6	0	0	110.9	Y249 F266	Y249-M262 HydrophobicContact CD2-CB 4.04Å; Y249-M262 HydrophobicContact CE2-CB 3.9Å; M262-F266 HydrophobicContact CE-CE2 3.69Å; M262-F266 HydrophobicContact CG-CD2 3.83Å; M262-F266 HydrophobicContact CG-CE2 3.6Å; M262-F266 WeakPolarHBondContact O-CD2 3.23Å; M262-F266 PolarHBondContact O-N 2.76Å
263	T	83.1	Confident	86.7	Confident	29 Å²	29	38.8 Å²	38.8	18%	0.178	20%	0.204	C	C	.	.	H	α-helix	trans	-58.9	-58.6	174.7	-46.9	0	0	0	0	112.1	T261 S265 F266 A267 A315 F319	T261-T263 PolarHBondContact O-N 3.29Å; T261-T263 WeakPolarHBondContact OG1-CB 3.29Å; T261-T263 PolarHBondContact OG1-N 3.11Å; T263-S265 PolarHBondContact O-N 3.01Å; T263-F266 PolarHBondContact O-N 3.02Å; T263-A267 WeakPolarHBondContact O-CB 3.49Å; T263-A267 PolarHBondContact O-N 2.66Å; T263-A315 WeakPolarHBondContact CG2-O 3.48Å; T263-F319 HydrophobicContact CG2-CB 3.5Å; T263-F319 HydrophobicContact CG2-CD2 4.44Å; T263-F319 HydrophobicContact CG2-CG 4.03Å; T263-F319 WeakPolarHBondContact OG1-CB 3.34Å; T263-F319 WeakPolarHBondContact OG1-CD1 3.25Å; T263-F319 WeakPolarHBondContact OG1-CG 3.41Å
264	D	85.5	Confident	86.8	Confident	10 Å²	10	34.5 Å²	34.5	5%	0.053	18%	0.184	C	C	.	.	H	α-helix	trans	-60.3	-37	-175.3	-38.3	-13.7	0	0	0	110.1	M260 T261 F268 L515 K520	M260-D264 HydrophobicContact CB-CB 4.38Å; M260-D264 HydrophobicContact CE-CB 3.5Å; T261-D264 WeakPolarHBondContact CG2-OD2 3.34Å; T261-D264 PolarHBondContact N-OD2 3.06Å; T261-D264 PolarHBondContact O-N 3.08Å; T261-D264 PolarHBondContact OG1-N 3.02Å; T261-D264 PolarHBondContact OG1-OD1 2.74Å; T261-D264 PolarHBondContact OG1-OD2 3.34Å; D264-F268 WeakPolarHBondContact O-CB 3.46Å; D264-F268 PolarHBondContact O-N 3.08Å; D264-L515 HydrophobicContact CB-CD1 4.3Å; D264-L515 HydrophobicContact CB-CD2 4.39Å; D264-K520 IonicContact OD1-NZ 3.86Å; D264-K520 WeakPolarHBondContact OD2-CD 3.45Å; D264-K520 VanDerWaalsContact OD2-CE 3.28Å; D264-K520 WeakPolarHBondContact OD2-CE 3.31Å; D264-K520 IonicContact OD2-NZ 2.75Å; D264-K520 PolarHBondContact OD2-NZ 3.1Å
265	S	89.3	Confident	86.7	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-67.1	-45.6	178.9	-51.2	0	0	0	0	112.2	G245 M260 T261 T263 F268 G269	G245-S265 WeakPolarHBondContact CA-O 3.2Å; G245-S265 VanDerWaalsContact O-CB 3.29Å; G245-S265 WeakPolarHBondContact O-CB 3.49Å; M260-S265 WeakPolarHBondContact CB-OG 3.3Å; T261-S265 WeakPolarHBondContact O-CB 3.44Å; T261-S265 PolarHBondContact O-N 3.27Å; T261-S265 PolarHBondContact O-OG 2.86Å; T263-S265 PolarHBondContact O-N 3.01Å; S265-F268 PolarHBondContact O-N 3.21Å; S265-G269 PolarHBondContact O-N 3Å
266	F	89.6	Confident	86.6	Confident	32 Å²	32	25.4 Å²	25.4	14%	0.14	13%	0.127	C	C	.	.	H	α-helix	trans	-74	-31.4	176.7	-74.3	-58.4	0	0	0	113.2	F242 G246 M262 T263 G269 S270	F242-F266 HydrophobicContact CD1-CD1 4.21Å; F242-F266 AromaticContact CD1-CE1 3.74Å; F242-F266 HydrophobicContact CD1-CE1 3.74Å; F242-F266 HydrophobicContact CD1-CZ 4.34Å; F242-F266 HydrophobicContact CE1-CE1 4.44Å; G246-F266 VanDerWaalsContact N-CE1 3.33Å; M262-F266 HydrophobicContact CE-CE2 3.69Å; M262-F266 HydrophobicContact CG-CD2 3.83Å; M262-F266 HydrophobicContact CG-CE2 3.6Å; M262-F266 WeakPolarHBondContact O-CD2 3.23Å; M262-F266 PolarHBondContact O-N 2.76Å; T263-F266 PolarHBondContact O-N 3.02Å; F266-G269 PolarHBondContact O-N 3.45Å; F266-S270 VanDerWaalsContact O-CB 3.31Å; F266-S270 WeakPolarHBondContact O-CB 3.41Å; F266-S270 PolarHBondContact O-N 3.37Å; F266-S270 PolarHBondContact O-OG 2.89Å
267	A	88.9	Confident	85.9	Confident	0 Å²	0	23 Å²	23	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-62	-45.5	169.9	0	0	0	0	0	110.8	T263 S270 L271 T312 A315 L513	T263-A267 WeakPolarHBondContact O-CB 3.49Å; T263-A267 PolarHBondContact O-N 2.66Å; A267-S270 WeakPolarHBondContact O-CB 3.44Å; A267-S270 PolarHBondContact O-N 3.03Å; A267-L271 PolarHBondContact O-N 2.75Å; A267-T312 HydrophobicContact CB-CG2 4.46Å; A267-A315 HydrophobicContact CB-CB 3.96Å; A267-L513 HydrophobicContact CB-CD1 4.37Å; A267-L513 HydrophobicContact CB-CD2 4.35Å
268	F	90.3	Very high	84.9	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-64	-44.7	173.8	-175.9	-93.7	0	0	0	112.8	V244 I248 D264 S265 S270 L271 I272 C461 I524 T527 T528 I531	V244-F268 HydrophobicContact CG1-CD1 4.38Å; V244-F268 HydrophobicContact CG1-CE1 4.44Å; I248-F268 HydrophobicContact CD1-CD1 3.3Å; I248-F268 HydrophobicContact CD1-CE1 3.63Å; I248-F268 HydrophobicContact CD1-CG 4.37Å; D264-F268 WeakPolarHBondContact O-CB 3.46Å; D264-F268 PolarHBondContact O-N 3.08Å; S265-F268 PolarHBondContact O-N 3.21Å; F268-S270 PolarHBondContact O-N 2.81Å; F268-L271 HydrophobicContact CD2-CD1 4.32Å; F268-L271 HydrophobicContact CD2-CD2 4.47Å; F268-L271 WeakPolarHBondContact O-CG 3.49Å; F268-L271 PolarHBondContact O-N 2.74Å; F268-I272 HydrophobicContact CD1-CG2 4.39Å; F268-I272 HydrophobicContact CE1-CB 4.49Å; F268-I272 HydrophobicContact CE1-CG2 4.2Å; F268-I272 WeakPolarHBondContact O-CB 3.21Å; F268-I272 VanDerWaalsContact O-CG2 3.23Å; F268-I272 WeakPolarHBondContact O-CG2 3.27Å; F268-I272 PolarHBondContact O-N 2.98Å; F268-C461 HydrophobicContact CE1-CB 4.43Å; F268-I524 HydrophobicContact CB-CD1 4.21Å; F268-I524 HydrophobicContact CD2-CB 4.22Å; F268-I524 HydrophobicContact CD2-CD1 4.09Å; F268-I524 HydrophobicContact CD2-CG1 3.65Å; F268-I524 HydrophobicContact CD2-CG2 3.88Å; F268-I524 HydrophobicContact CE2-CG1 4.19Å; F268-I524 HydrophobicContact CE2-CG2 4.26Å; F268-I524 HydrophobicContact CG-CG1 4.4Å; F268-T527 HydrophobicContact CZ-CG2 3.95Å; F268-T528 WeakPolarHBondContact CE2-OG1 3.35Å; F268-I531 HydrophobicContact CZ-CD1 4.08Å
269	G	91.8	Very high	84.2	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-58.4	-35.6	174.6	0	0	0	0	0	112.6	A241 S265 F266 S273	A241-G269 WeakPolarHBondContact CA-O 3.47Å; A241-G269 WeakPolarHBondContact CB-O 3.43Å; S265-G269 PolarHBondContact O-N 3Å; F266-G269 PolarHBondContact O-N 3.45Å; G269-S273 WeakPolarHBondContact O-CB 3.35Å; G269-S273 PolarHBondContact O-N 3.06Å; G269-S273 PolarHBondContact O-OG 2.89Å
270	S	91.5	Very high	83.5	Confident	4 Å²	4	14.1 Å²	14.1	3%	0.028	8%	0.078	C	C	.	.	H	α-helix	trans	-70.9	-53.9	176.4	-57.4	0	0	0	0	111.8	F266 A267 F268 I272 S273 S308 L311 T312	F266-S270 VanDerWaalsContact O-CB 3.31Å; F266-S270 WeakPolarHBondContact O-CB 3.41Å; F266-S270 PolarHBondContact O-N 3.37Å; F266-S270 PolarHBondContact O-OG 2.89Å; A267-S270 WeakPolarHBondContact O-CB 3.44Å; A267-S270 PolarHBondContact O-N 3.03Å; F268-S270 PolarHBondContact O-N 2.81Å; S270-I272 VanDerWaalsContact C-N 3.28Å; S270-I272 PolarHBondContact O-N 3.45Å; S270-S273 WeakPolarHBondContact O-CB 3.37Å; S270-S273 PolarHBondContact O-N 3.27Å; S270-S308 WeakPolarHBondContact O-CB 3.42Å; S270-L311 WeakPolarHBondContact OG-CD2 3.49Å; S270-L311 WeakPolarHBondContact OG-CG 3.43Å; S270-T312 WeakPolarHBondContact CB-OG1 3.31Å
271	L	90.3	Very high	83	Confident	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-62.9	-34.1	-176.8	71.1	88.4	0	0	0	112.9	A267 F268 S273 T312 P506 L509 L513 T528	A267-L271 PolarHBondContact O-N 2.75Å; F268-L271 HydrophobicContact CD2-CD1 4.32Å; F268-L271 HydrophobicContact CD2-CD2 4.47Å; F268-L271 WeakPolarHBondContact O-CG 3.49Å; F268-L271 PolarHBondContact O-N 2.74Å; L271-S273 VanDerWaalsContact C-N 3.29Å; L271-S273 PolarHBondContact O-N 3.3Å; L271-T312 HydrophobicContact CB-CG2 4.34Å; L271-T312 PolarHBondContact N-OG1 2.73Å; L271-P506 HydrophobicContact CD1-CB 4.43Å; L271-P506 WeakPolarHBondContact O-CA 3.29Å; L271-P506 WeakPolarHBondContact O-CB 3.38Å; L271-P506 WeakPolarHBondContact O-CG 3.46Å; L271-L509 HydrophobicContact CB-CB 4.24Å; L271-L509 HydrophobicContact CB-CD2 3.56Å; L271-L509 HydrophobicContact CB-CG 3.82Å; L271-L513 HydrophobicContact CD2-CD1 4.09Å; L271-L513 HydrophobicContact CD2-CD2 3.68Å; L271-L513 HydrophobicContact CD2-CG 4.5Å; L271-T528 HydrophobicContact CD1-CG2 4.25Å
272	I	91.2	Very high	81.9	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.07	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83	-3	178.3	-154	61.1	0	0	0	113.1	V244 F268 S270 V465 R502 P506 T528 I531	V244-I272 HydrophobicContact CG1-CG2 3.85Å; F268-I272 HydrophobicContact CD1-CG2 4.39Å; F268-I272 HydrophobicContact CE1-CB 4.49Å; F268-I272 HydrophobicContact CE1-CG2 4.2Å; F268-I272 WeakPolarHBondContact O-CB 3.21Å; F268-I272 VanDerWaalsContact O-CG2 3.23Å; F268-I272 WeakPolarHBondContact O-CG2 3.27Å; F268-I272 PolarHBondContact O-N 2.98Å; S270-I272 VanDerWaalsContact C-N 3.28Å; S270-I272 PolarHBondContact O-N 3.45Å; I272-V465 HydrophobicContact CG1-CG2 3.92Å; I272-V465 HydrophobicContact CG2-CG2 3.97Å; I272-R502 WeakPolarHBondContact O-CD 3.24Å; I272-R502 PolarHBondContact O-NE 3.42Å; I272-R502 PolarHBondContact O-NH1 3.42Å; I272-P506 HydrophobicContact CD1-CB 4.02Å; I272-T528 HydrophobicContact CD1-CG2 4.08Å; I272-I531 HydrophobicContact CD1-CB 4.24Å; I272-I531 HydrophobicContact CD1-CD1 4.35Å; I272-I531 HydrophobicContact CD1-CG2 3.89Å; I272-I531 HydrophobicContact CG1-CD1 4.24Å; I272-I531 HydrophobicContact CG1-CG2 4.15Å
273	S	90.9	Very high	81.1	Confident	1 Å²	1	8.4 Å²	8.4	1%	0.007	5%	0.049	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.6	-14.7	178.6	-72.8	0	0	0	0	114.5	S240 A241 G269 S270 L271 N304 R502	S240-S273 WeakPolarHBondContact CB-OG 3.16Å; S240-S273 PolarHBondContact OG-OG 2.86Å; A241-S273 WeakPolarHBondContact CA-OG 3.12Å; A241-S273 PolarHBondContact N-OG 3.14Å; A241-S273 VanDerWaalsContact N-OG 3.13Å; G269-S273 WeakPolarHBondContact O-CB 3.35Å; G269-S273 PolarHBondContact O-N 3.06Å; G269-S273 PolarHBondContact O-OG 2.89Å; S270-S273 WeakPolarHBondContact O-CB 3.37Å; S270-S273 PolarHBondContact O-N 3.27Å; L271-S273 VanDerWaalsContact C-N 3.29Å; L271-S273 PolarHBondContact O-N 3.3Å; S273-N304 PolarHBondContact O-ND2 2.86Å; S273-N304 PolarHBondContact O-OD1 3.29Å; S273-N304 VanDerWaalsContact O-OD1 3.13Å; S273-R502 PolarHBondContact O-NH1 2.84Å
274	A	88.7	Confident	80.5	Confident	1 Å²	1	7.1 Å²	7.1	1%	0.008	4%	0.041	C	C	.	.			trans	-56.3	142.3	166.4	0	0	0	0	0	112.4	N304 D305 S308 R502 P506	A274-N304 WeakPolarHBondContact CA-OD1 3.44Å; A274-D305 VanDerWaalsContact CB-OD1 3.28Å; A274-D305 WeakPolarHBondContact CB-OD1 3.46Å; A274-S308 PolarHBondContact N-OG 3.03Å; A274-R502 WeakPolarHBondContact O-CD 3.43Å; A274-R502 PolarHBondContact O-NH1 3.11Å; A274-P506 HydrophobicContact CB-CG 3.91Å
275	V	86.8	Confident	79.3	Confident	0 Å²	0	10.2 Å²	10.2	0%	0	6%	0.058	C	C	.	.			trans	-133.3	132.6	-173	172.3	0	0	0	0	109.1	S301 N304 L501	V275-S301 WeakPolarHBondContact O-CB 3.43Å; V275-S301 PolarHBondContact O-OG 3.5Å; V275-N304 WeakPolarHBondContact CG2-ND2 3.48Å; V275-N304 PolarHBondContact N-ND2 3Å; V275-L501 CarbonylContact C-O 3.56Å; V275-L501 WeakPolarHBondContact CA-O 3.48Å
276	D	80.8	Confident	77.9	Confident	19 Å²	19	10.9 Å²	10.9	10%	0.102	6%	0.063	C	C	.	.			trans	-99.3	124	-175.7	-176	-25.3	0	0	0	111	V278 F439 L501 G503	D276-V278 WeakPolarHBondContact OD1-CB 3.33Å; D276-V278 WeakPolarHBondContact OD1-CG2 3.5Å; D276-V278 PolarHBondContact OD1-N 3.44Å; D276-F439 WeakPolarHBondContact OD2-CZ 3.49Å; D276-L501 PolarHBondContact N-O 3.06Å; D276-G503 VanDerWaalsContact CB-CA 3.45Å; D276-G503 WeakPolarHBondContact OD2-CA 3.27Å
277	P	68.5	Low	76.7	Confident	15 Å²	15	10.9 Å²	10.9	10%	0.097	7%	0.065	C	C	.	.			trans	-90	-9.7	-177.9	35.6	-30	0	0	0	113.2	A279 T280 I281 F298	P277-A279 PolarHBondContact O-N 3.21Å; P277-T280 PolarHBondContact O-N 3.4Å; P277-I281 HydrophobicContact CB-CD1 3.7Å; P277-I281 HydrophobicContact CB-CG1 4.12Å; P277-I281 HydrophobicContact CG-CD1 4.46Å; P277-I281 WeakPolarHBondContact O-CB 3.32Å; P277-I281 WeakPolarHBondContact O-CG1 3.19Å; P277-I281 PolarHBondContact O-N 2.99Å; P277-F298 HydrophobicContact CG-CD2 4.44Å
278	V	65.1	Low	75.6	Confident	16 Å²	16	17.8 Å²	17.8	10%	0.097	10%	0.102	C	C	.	.	H	α-helix	trans	-55.6	-55.5	-162.8	165.3	0	0	0	0	112.6	S165 D276 A282 K569	S165-V278 WeakPolarHBondContact OG-CG1 3.24Å; D276-V278 WeakPolarHBondContact OD1-CB 3.33Å; D276-V278 WeakPolarHBondContact OD1-CG2 3.5Å; D276-V278 PolarHBondContact OD1-N 3.44Å; V278-A282 PolarHBondContact O-N 2.67Å; V278-K569 HydrophobicContact CG1-CD 4.49Å
279	A	65.6	Low	74.6	Confident	10 Å²	10	19.1 Å²	19.1	8%	0.083	11%	0.11	C	C	.	.	H	α-helix	trans	-76.1	-33.3	-179.8	0	0	0	0	0	112.2	P163 P277 A282 I283 L501	P163-A279 HydrophobicContact CB-CB 3.85Å; P163-A279 HydrophobicContact CG-CB 4.15Å; P277-A279 PolarHBondContact O-N 3.21Å; A279-A282 PolarHBondContact O-N 2.73Å; A279-I283 WeakPolarHBondContact O-CD1 3.47Å; A279-I283 WeakPolarHBondContact O-CG1 3.43Å; A279-I283 PolarHBondContact O-N 2.76Å; A279-L501 HydrophobicContact CB-CD1 3.78Å
280	T	67.6	Low	73.7	Confident	1 Å²	1	21.2 Å²	21.2	1%	0.006	12%	0.121	C	C	.	.	H	α-helix	trans	-61	-52	178.5	-70.1	0	0	0	0	111.9	P277 A282 I283 F284 V297 S499	P277-T280 PolarHBondContact O-N 3.4Å; T280-A282 VanDerWaalsContact C-N 3.33Å; T280-A282 PolarHBondContact O-N 2.87Å; T280-I283 PolarHBondContact O-N 3.28Å; T280-F284 HydrophobicContact CG2-CD1 4.15Å; T280-F284 HydrophobicContact CG2-CD2 4.04Å; T280-F284 HydrophobicContact CG2-CE1 3.67Å; T280-F284 HydrophobicContact CG2-CE2 3.57Å; T280-F284 HydrophobicContact CG2-CG 4.32Å; T280-F284 HydrophobicContact CG2-CZ 3.35Å; T280-F284 WeakPolarHBondContact O-CD1 3.25Å; T280-F284 WeakPolarHBondContact O-CG 3.49Å; T280-F284 PolarHBondContact O-N 3.24Å; T280-V297 HydrophobicContact CG2-CG1 3.95Å; T280-S499 PolarHBondContact OG1-O 3.4Å; T280-S499 VanDerWaalsContact OG1-O 3.08Å
281	I	69.9	Low	72.8	Confident	24 Å²	24	25 Å²	25	12%	0.123	15%	0.145	C	C	.	.	H	α-helix	trans	-65.3	-38.6	-179.2	-69.2	178.3	0	0	0	111.1	P277 I283 F284 N285 F298	P277-I281 HydrophobicContact CB-CD1 3.7Å; P277-I281 HydrophobicContact CB-CG1 4.12Å; P277-I281 HydrophobicContact CG-CD1 4.46Å; P277-I281 WeakPolarHBondContact O-CB 3.32Å; P277-I281 WeakPolarHBondContact O-CG1 3.19Å; P277-I281 PolarHBondContact O-N 2.99Å; I281-I283 PolarHBondContact O-N 2.94Å; I281-F284 PolarHBondContact O-N 2.84Å; I281-N285 VanDerWaalsContact CG2-ND2 3.31Å; I281-N285 WeakPolarHBondContact CG2-ND2 3.34Å; I281-N285 VanDerWaalsContact O-CB 3.23Å; I281-N285 WeakPolarHBondContact O-CB 3.1Å; I281-N285 PolarHBondContact O-N 2.99Å; I281-F298 HydrophobicContact CD1-CB 3.48Å; I281-F298 VanDerWaalsContact CD1-CB 3.48Å; I281-F298 HydrophobicContact CD1-CD2 3.18Å; I281-F298 HydrophobicContact CD1-CE2 4.03Å; I281-F298 HydrophobicContact CD1-CG 3.56Å
282	A	62	Low	72.2	Confident	12 Å²	12	26.8 Å²	26.8	10%	0.099	16%	0.156	C	C	.	.	H	α-helix	trans	-56.9	-40.5	176.4	0	0	0	0	0	111.9	V278 A279 T280 A286	V278-A282 PolarHBondContact O-N 2.67Å; A279-A282 PolarHBondContact O-N 2.73Å; T280-A282 VanDerWaalsContact C-N 3.33Å; T280-A282 PolarHBondContact O-N 2.87Å; A282-A286 WeakPolarHBondContact O-CB 3.43Å; A282-A286 PolarHBondContact O-N 3.26Å
283	I	65.6	Low	71.6	Confident	3 Å²	3	27 Å²	27	2%	0.015	16%	0.157	C	C	.	.	H	α-helix	trans	-74.8	-45.8	176.3	-60.2	163.6	0	0	0	111.4	A279 T280 I281 N285 A286 L287 T543 M544 I547 L567	A279-I283 WeakPolarHBondContact O-CD1 3.47Å; A279-I283 WeakPolarHBondContact O-CG1 3.43Å; A279-I283 PolarHBondContact O-N 2.76Å; T280-I283 PolarHBondContact O-N 3.28Å; I281-I283 PolarHBondContact O-N 2.94Å; I283-N285 VanDerWaalsContact C-N 3.35Å; I283-N285 PolarHBondContact O-N 3.22Å; I283-A286 WeakPolarHBondContact O-CA 3.31Å; I283-A286 WeakPolarHBondContact O-CB 3.46Å; I283-A286 PolarHBondContact O-N 3.5Å; I283-L287 HydrophobicContact CG2-CD1 3.76Å; I283-L287 HydrophobicContact CG2-CG 4.42Å; I283-L287 PolarHBondContact O-N 3.48Å; I283-L287 VanDerWaalsContact O-N 3.09Å; I283-T543 HydrophobicContact CB-CG2 4.43Å; I283-T543 HydrophobicContact CD1-CG2 3.83Å; I283-T543 HydrophobicContact CG2-CG2 4.19Å; I283-M544 HydrophobicContact CD1-CB 4.41Å; I283-M544 HydrophobicContact CG2-CB 4.19Å; I283-M544 HydrophobicContact CG2-CG 4.4Å; I283-I547 HydrophobicContact CG2-CD1 3.85Å; I283-L567 HydrophobicContact CB-CD2 4.4Å; I283-L567 HydrophobicContact CG1-CD2 3.92Å
284	F	70.3	Confident	71.1	Confident	1 Å²	1	28.2 Å²	28.2	0%	0.004	16%	0.164	C	C	.	.	H	α-helix	trans	-57.3	-46.6	177.5	-72.5	5	0	0	0	111.7	T280 I281 A286 L287 N288 V289 L293 N294 V297 I495 I547	T280-F284 HydrophobicContact CG2-CD1 4.15Å; T280-F284 HydrophobicContact CG2-CD2 4.04Å; T280-F284 HydrophobicContact CG2-CE1 3.67Å; T280-F284 HydrophobicContact CG2-CE2 3.57Å; T280-F284 HydrophobicContact CG2-CG 4.32Å; T280-F284 HydrophobicContact CG2-CZ 3.35Å; T280-F284 WeakPolarHBondContact O-CD1 3.25Å; T280-F284 WeakPolarHBondContact O-CG 3.49Å; T280-F284 PolarHBondContact O-N 3.24Å; I281-F284 PolarHBondContact O-N 2.84Å; F284-A286 PolarHBondContact O-N 3.45Å; F284-L287 PolarHBondContact O-N 2.82Å; F284-N288 PolarHBondContact O-N 2.92Å; F284-N288 VanDerWaalsContact O-N 3.15Å; F284-V289 HydrophobicContact CB-CB 4.06Å; F284-V289 HydrophobicContact CB-CG2 4.18Å; F284-V289 HydrophobicContact CD1-CG2 4.28Å; F284-V289 HydrophobicContact CG-CB 4.31Å; F284-V289 HydrophobicContact CG-CG1 4.38Å; F284-V289 HydrophobicContact CG-CG2 4.33Å; F284-V289 PolarHBondContact O-N 2.91Å; F284-L293 HydrophobicContact CE2-CG 4.26Å; F284-N294 HydrophobicContact CD2-CB 4.36Å; F284-V297 HydrophobicContact CE2-CB 4.2Å; F284-V297 HydrophobicContact CE2-CG1 4.48Å; F284-V297 HydrophobicContact CE2-CG2 4.05Å; F284-I495 HydrophobicContact CE1-CG2 3.56Å; F284-I495 HydrophobicContact CZ-CG2 3.45Å; F284-I495 VanDerWaalsContact CZ-CG2 3.45Å; F284-I547 HydrophobicContact CD1-CD1 3.69Å; F284-I547 HydrophobicContact CE1-CD1 3.71Å
285	N	61.5	Low	70.6	Confident	76 Å²	76	29.1 Å²	29.1	41%	0.406	17%	0.168	S	C	.	.	T	Hydrogen-bonded Turn	trans	-68.3	-10.3	174.9	-73.1	-14.1	0	0	0	113.7	I281 I283 N294 K572	I281-N285 VanDerWaalsContact CG2-ND2 3.31Å; I281-N285 WeakPolarHBondContact CG2-ND2 3.34Å; I281-N285 VanDerWaalsContact O-CB 3.23Å; I281-N285 WeakPolarHBondContact O-CB 3.1Å; I281-N285 PolarHBondContact O-N 2.99Å; I283-N285 VanDerWaalsContact C-N 3.35Å; I283-N285 PolarHBondContact O-N 3.22Å; N285-N294 PolarHBondContact OD1-ND2 3.13Å; N285-K572 PolarHBondContact O-NZ 3.41Å
286	A	59.6	Low	70.5	Confident	14 Å²	14	29.3 Å²	29.3	12%	0.116	17%	0.169	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.9	-17	175.1	0	0	0	0	0	112.5	A282 I283 F284 V565 N566 L567	A282-A286 WeakPolarHBondContact O-CB 3.43Å; A282-A286 PolarHBondContact O-N 3.26Å; I283-A286 WeakPolarHBondContact O-CA 3.31Å; I283-A286 WeakPolarHBondContact O-CB 3.46Å; I283-A286 PolarHBondContact O-N 3.5Å; F284-A286 PolarHBondContact O-N 3.45Å; A286-V565 HydrophobicContact CB-CG1 3.7Å; A286-N566 WeakPolarHBondContact CB-O 3.47Å; A286-L567 HydrophobicContact CB-CD2 3.77Å
287	L	63.8	Low	70.6	Confident	32 Å²	32	28.5 Å²	28.5	17%	0.168	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112	8.7	-179	-60.3	176.5	0	0	0	112.9	I283 F284 V289 I547 V565	I283-L287 HydrophobicContact CG2-CD1 3.76Å; I283-L287 HydrophobicContact CG2-CG 4.42Å; I283-L287 PolarHBondContact O-N 3.48Å; I283-L287 VanDerWaalsContact O-N 3.09Å; F284-L287 PolarHBondContact O-N 2.82Å; L287-V289 HydrophobicContact CB-CG2 4.18Å; L287-V289 PolarHBondContact O-N 3.14Å; L287-I547 HydrophobicContact CB-CG2 4.4Å; L287-I547 HydrophobicContact CD1-CB 3.63Å; L287-I547 HydrophobicContact CD1-CD1 4.19Å; L287-I547 HydrophobicContact CD1-CG2 3.49Å; L287-I547 VanDerWaalsContact CD1-CG2 3.49Å; L287-V565 HydrophobicContact CD2-CG1 3.95Å; L287-V565 HydrophobicContact CD2-CG2 4.29Å
288	N	65.8	Low	71.3	Confident	145 Å²	145	29.9 Å²	29.9	78%	0.775	17%	0.169	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.5	40.3	-179.3	-61.5	-38.1	0	0	0	113.6	F284	F284-N288 PolarHBondContact O-N 2.92Å; F284-N288 VanDerWaalsContact O-N 3.15Å
289	V	68.4	Low	72.1	Confident	28 Å²	28	29.1 Å²	29.1	17%	0.17	17%	0.165	C	C	.	.			trans	-61.8	148	175.8	178.2	0	0	0	0	110.2	F284 L287 L293 I547	F284-V289 HydrophobicContact CB-CB 4.06Å; F284-V289 HydrophobicContact CB-CG2 4.18Å; F284-V289 HydrophobicContact CD1-CG2 4.28Å; F284-V289 HydrophobicContact CG-CB 4.31Å; F284-V289 HydrophobicContact CG-CG1 4.38Å; F284-V289 HydrophobicContact CG-CG2 4.33Å; F284-V289 PolarHBondContact O-N 2.91Å; L287-V289 HydrophobicContact CB-CG2 4.18Å; L287-V289 PolarHBondContact O-N 3.14Å; V289-L293 HydrophobicContact CG1-CB 4.31Å; V289-L293 HydrophobicContact CG1-CD2 3.57Å; V289-L293 HydrophobicContact CG1-CG 4.09Å; V289-I547 HydrophobicContact CG2-CG2 4.29Å
290	D	73.2	Confident	73.2	Confident	43 Å²	43	28.8 Å²	28.8	23%	0.23	16%	0.161	C	C	.	.			trans	-39	119.2	177	177.3	3.2	0	0	0	112.4	V292 L293 N294 H486 M492	D290-V292 PolarHBondContact O-N 3.35Å; D290-V292 VanDerWaalsContact OD1-CB 3.31Å; D290-V292 WeakPolarHBondContact OD1-CB 3.16Å; D290-V292 WeakPolarHBondContact OD1-CG2 3.29Å; D290-V292 PolarHBondContact OD1-N 2.75Å; D290-L293 HydrophobicContact CB-CB 4.19Å; D290-L293 PolarHBondContact O-N 3.42Å; D290-N294 PolarHBondContact O-N 3.29Å; D290-H486 IonicContact OD2-CE1 2.82Å; D290-H486 PolarHBondContact OD2-CE1 3.11Å; D290-M492 HydrophobicContact CB-CE 4.01Å; D290-M492 WeakPolarHBondContact OD2-CE 3.49Å
291	P	73.4	Confident	74.1	Confident	83 Å²	83	28.7 Å²	28.7	54%	0.539	16%	0.161	S	C	.	.	H	α-helix	trans	-52.6	-29.3	176.9	-28.3	35.7	0	0	0	113.8	M295	P291-M295 WeakPolarHBondContact O-CB 3.48Å; P291-M295 PolarHBondContact O-N 3.01Å
292	V	77.2	Confident	74.8	Confident	38 Å²	38	27.9 Å²	27.9	23%	0.23	16%	0.157	C	C	.	.	H	α-helix	trans	-69.6	-43.4	176.8	-177.9	0	0	0	0	111.3	D290 L296	D290-V292 PolarHBondContact O-N 3.35Å; D290-V292 VanDerWaalsContact OD1-CB 3.31Å; D290-V292 WeakPolarHBondContact OD1-CB 3.16Å; D290-V292 WeakPolarHBondContact OD1-CG2 3.29Å; D290-V292 PolarHBondContact OD1-N 2.75Å; V292-L296 HydrophobicContact CG1-CD1 4.2Å; V292-L296 WeakPolarHBondContact O-CD1 3.48Å; V292-L296 WeakPolarHBondContact O-CG 3.27Å; V292-L296 PolarHBondContact O-N 2.78Å
293	L	79.4	Confident	76	Confident	5 Å²	5	27.9 Å²	27.9	3%	0.026	16%	0.155	C	C	.	.	H	α-helix	trans	-65.1	-43.6	175.1	170	57.3	0	0	0	111.1	F284 V289 D290 L296 V297 M492 I495 M496	F284-L293 HydrophobicContact CE2-CG 4.26Å; V289-L293 HydrophobicContact CG1-CB 4.31Å; V289-L293 HydrophobicContact CG1-CD2 3.57Å; V289-L293 HydrophobicContact CG1-CG 4.09Å; D290-L293 HydrophobicContact CB-CB 4.19Å; D290-L293 PolarHBondContact O-N 3.42Å; L293-L296 PolarHBondContact O-N 2.95Å; L293-V297 HydrophobicContact CD1-CG2 4.05Å; L293-V297 PolarHBondContact O-N 2.99Å; L293-V297 VanDerWaalsContact O-N 3.14Å; L293-M492 HydrophobicContact CD1-CB 4.42Å; L293-M492 HydrophobicContact CD2-CB 4.16Å; L293-M492 HydrophobicContact CD2-CG 3.98Å; L293-I495 HydrophobicContact CD2-CB 4.38Å; L293-I495 HydrophobicContact CD2-CD1 4.41Å; L293-I495 HydrophobicContact CD2-CG2 4.04Å; L293-M496 HydrophobicContact CD1-CG 3.28Å; L293-M496 HydrophobicContact CD1-SD 3.82Å
294	N	79.1	Confident	77.2	Confident	26 Å²	26	27.7 Å²	27.7	14%	0.139	15%	0.154	C	C	.	.	H	α-helix	trans	-59	-48.8	177.2	-166.9	20.7	0	0	0	111.8	F284 N285 D290 L296 V297 F298	F284-N294 HydrophobicContact CD2-CB 4.36Å; N285-N294 PolarHBondContact OD1-ND2 3.13Å; D290-N294 PolarHBondContact O-N 3.29Å; N294-L296 PolarHBondContact O-N 3.02Å; N294-V297 PolarHBondContact O-N 3.41Å; N294-F298 VanDerWaalsContact O-CB 3.29Å; N294-F298 WeakPolarHBondContact O-CB 3.48Å; N294-F298 PolarHBondContact O-N 3.29Å
295	M	79	Confident	78.1	Confident	20 Å²	20	28.4 Å²	28.4	10%	0.099	16%	0.158	C	C	.	.	H	α-helix	trans	-59.4	-42.1	175.7	167.4	-86.5	172.9	0	0	112.9	N221 F222 N225 I229 P291 G299	N221-M295 WeakPolarHBondContact O-CE 3.36Å; F222-M295 HydrophobicContact CD2-CE 4.17Å; F222-M295 VanDerWaalsContact O-CE 3.24Å; F222-M295 WeakPolarHBondContact O-CE 3.49Å; N225-M295 HydrophobicContact CB-CE 3.52Å; N225-M295 HydrophobicContact CB-SD 3.92Å; I229-M295 HydrophobicContact CD1-CE 3.11Å; I229-M295 HydrophobicContact CD1-SD 3.82Å; I229-M295 HydrophobicContact CG1-CE 3.88Å; I229-M295 HydrophobicContact CG1-SD 4.43Å; P291-M295 WeakPolarHBondContact O-CB 3.48Å; P291-M295 PolarHBondContact O-N 3.01Å; M295-G299 PolarHBondContact O-N 3.3Å; M295-G299 VanDerWaalsContact O-N 3.09Å
296	L	83.9	Confident	79.3	Confident	5 Å²	5	24.8 Å²	24.8	3%	0.026	14%	0.139	C	C	.	.	H	α-helix	trans	-62.9	-49.2	179.2	-73	163.6	0	0	0	111.6	I229 F232 V292 L293 N294 E300 I488	I229-L296 HydrophobicContact CG1-CD2 4.11Å; F232-L296 HydrophobicContact CE2-CD2 4.47Å; V292-L296 HydrophobicContact CG1-CD1 4.2Å; V292-L296 WeakPolarHBondContact O-CD1 3.48Å; V292-L296 WeakPolarHBondContact O-CG 3.27Å; V292-L296 PolarHBondContact O-N 2.78Å; L293-L296 PolarHBondContact O-N 2.95Å; N294-L296 PolarHBondContact O-N 3.02Å; L296-E300 WeakPolarHBondContact O-CB 3.28Å; L296-E300 PolarHBondContact O-N 3.28Å; L296-I488 HydrophobicContact CD1-CD1 4.18Å; L296-I488 HydrophobicContact CD1-CG1 4.43Å
297	V	84.5	Confident	80.8	Confident	1 Å²	1	24.2 Å²	24.2	1%	0.006	13%	0.134	C	C	.	.	H	α-helix	trans	-69.5	-38.2	-178.3	177.3	0	0	0	0	111.7	T280 F284 L293 N294 S301 M496	T280-V297 HydrophobicContact CG2-CG1 3.95Å; F284-V297 HydrophobicContact CE2-CB 4.2Å; F284-V297 HydrophobicContact CE2-CG1 4.48Å; F284-V297 HydrophobicContact CE2-CG2 4.05Å; L293-V297 HydrophobicContact CD1-CG2 4.05Å; L293-V297 PolarHBondContact O-N 2.99Å; L293-V297 VanDerWaalsContact O-N 3.14Å; N294-V297 PolarHBondContact O-N 3.41Å; V297-S301 WeakPolarHBondContact O-CB 3.13Å; V297-S301 PolarHBondContact O-N 2.86Å; V297-S301 VanDerWaalsContact O-N 3.1Å; V297-S301 PolarHBondContact O-OG 2.99Å; V297-M496 HydrophobicContact CG2-CB 4.38Å; V297-M496 HydrophobicContact CG2-CG 3.69Å; V297-M496 HydrophobicContact CG2-SD 4.35Å
298	F	81.7	Confident	82	Confident	44 Å²	44	22.7 Å²	22.7	19%	0.193	13%	0.126	C	C	.	.	H	α-helix	trans	-59	-57.4	176.4	-178.5	-140	0	0	0	111.9	L217 P277 I281 N294 S301 I302	L217-F298 HydrophobicContact CD1-CD1 3.99Å; L217-F298 HydrophobicContact CD1-CE1 3.68Å; L217-F298 HydrophobicContact CD1-CZ 4.5Å; P277-F298 HydrophobicContact CG-CD2 4.44Å; I281-F298 HydrophobicContact CD1-CB 3.48Å; I281-F298 VanDerWaalsContact CD1-CB 3.48Å; I281-F298 HydrophobicContact CD1-CD2 3.18Å; I281-F298 HydrophobicContact CD1-CE2 4.03Å; I281-F298 HydrophobicContact CD1-CG 3.56Å; N294-F298 VanDerWaalsContact O-CB 3.29Å; N294-F298 WeakPolarHBondContact O-CB 3.48Å; N294-F298 PolarHBondContact O-N 3.29Å; F298-S301 PolarHBondContact O-N 3.39Å; F298-I302 HydrophobicContact CD1-CD1 4.27Å; F298-I302 HydrophobicContact CD2-CD1 3.6Å; F298-I302 HydrophobicContact CD2-CG1 4.3Å; F298-I302 HydrophobicContact CE1-CD1 3.98Å; F298-I302 HydrophobicContact CE2-CD1 3.29Å; F298-I302 HydrophobicContact CE2-CG1 4.22Å; F298-I302 HydrophobicContact CG-CD1 4.12Å; F298-I302 HydrophobicContact CZ-CD1 3.49Å; F298-I302 VanDerWaalsContact CZ-CD1 3.49Å; F298-I302 WeakPolarHBondContact O-CG1 3.4Å; F298-I302 PolarHBondContact O-N 3.1Å; F298-I302 VanDerWaalsContact O-N 3.12Å
299	G	83.3	Confident	83	Confident	1 Å²	1	15.9 Å²	15.9	1%	0.01	9%	0.089	C	C	.	.	H	α-helix	trans	-78.8	-20.7	-176.7	0	0	0	0	0	113.8	I229 M295 L303	I229-G299 VanDerWaalsContact CG2-C 3.43Å; I229-G299 VanDerWaalsContact CG2-O 3.28Å; I229-G299 WeakPolarHBondContact CG2-O 3.29Å; M295-G299 PolarHBondContact O-N 3.3Å; M295-G299 VanDerWaalsContact O-N 3.09Å; G299-L303 PolarHBondContact O-N 2.93Å
300	E	88.1	Confident	84	Confident	2 Å²	2	14.6 Å²	14.6	1%	0.009	8%	0.082	C	C	.	.	H	α-helix	trans	-57.1	-57.8	164.2	-175.5	-138.6	133.1	0	0	109.1	F232 L296 I302 L303 N304 R469	F232-E300 HydrophobicContact CB-CG 3.84Å; L296-E300 WeakPolarHBondContact O-CB 3.28Å; L296-E300 PolarHBondContact O-N 3.28Å; E300-I302 PolarHBondContact O-N 3.44Å; E300-L303 PolarHBondContact O-N 3.08Å; E300-N304 WeakPolarHBondContact O-CA 3.31Å; E300-N304 WeakPolarHBondContact O-CB 3.39Å; E300-N304 PolarHBondContact O-N 2.71Å; E300-N304 PolarHBondContact OE1-ND2 3.03Å; E300-R469 VanDerWaalsContact CD-NH1 3.29Å; E300-R469 IonicContact OE1-CZ 3.65Å; E300-R469 IonicContact OE1-NH1 3.21Å; E300-R469 PolarHBondContact OE1-NH1 2.79Å; E300-R469 IonicContact OE1-NH2 3.91Å; E300-R469 IonicContact OE2-CZ 3.02Å; E300-R469 IonicContact OE2-NH1 2.99Å; E300-R469 PolarHBondContact OE2-NH1 3.25Å; E300-R469 VanDerWaalsContact OE2-NH1 3.12Å; E300-R469 IonicContact OE2-NH2 3.96Å; E300-R469 PolarHBondContact OE2-NH2 3.41Å
301	S	86.8	Confident	84.8	Confident	0 Å²	0	13.7 Å²	13.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-55.3	-50.1	-177	-60.6	0	0	0	0	112.3	V275 V297 F298 L303 N304 D305	V275-S301 WeakPolarHBondContact O-CB 3.43Å; V275-S301 PolarHBondContact O-OG 3.5Å; V297-S301 WeakPolarHBondContact O-CB 3.13Å; V297-S301 PolarHBondContact O-N 2.86Å; V297-S301 VanDerWaalsContact O-N 3.1Å; V297-S301 PolarHBondContact O-OG 2.99Å; F298-S301 PolarHBondContact O-N 3.39Å; S301-L303 PolarHBondContact O-N 2.84Å; S301-N304 WeakPolarHBondContact O-CB 3.47Å; S301-N304 PolarHBondContact O-N 3.31Å; S301-N304 VanDerWaalsContact O-N 3.15Å; S301-D305 PolarHBondContact O-N 3.06Å
302	I	84.8	Confident	85.4	Confident	6 Å²	6	9.8 Å²	9.8	3%	0.031	5%	0.051	C	C	.	.	H	α-helix	trans	-58.2	-47.3	-179.1	-69.9	170.3	0	0	0	112.4	S213 L217 F298 E300 L401	S213-I302 WeakPolarHBondContact O-CD1 3.33Å; L217-I302 HydrophobicContact CD1-CD1 4.25Å; F298-I302 HydrophobicContact CD1-CD1 4.27Å; F298-I302 HydrophobicContact CD2-CD1 3.6Å; F298-I302 HydrophobicContact CD2-CG1 4.3Å; F298-I302 HydrophobicContact CE1-CD1 3.98Å; F298-I302 HydrophobicContact CE2-CD1 3.29Å; F298-I302 HydrophobicContact CE2-CG1 4.22Å; F298-I302 HydrophobicContact CG-CD1 4.12Å; F298-I302 HydrophobicContact CZ-CD1 3.49Å; F298-I302 VanDerWaalsContact CZ-CD1 3.49Å; F298-I302 WeakPolarHBondContact O-CG1 3.4Å; F298-I302 PolarHBondContact O-N 3.1Å; F298-I302 VanDerWaalsContact O-N 3.12Å; E300-I302 PolarHBondContact O-N 3.44Å; I302-L401 HydrophobicContact CG2-CD1 3.45Å; I302-L401 VanDerWaalsContact CG2-CD1 3.45Å; I302-L401 HydrophobicContact CG2-CD2 4.03Å; I302-L401 HydrophobicContact CG2-CG 4.36Å; I302-L401 WeakPolarHBondContact O-CD2 3.5Å
303	L	87.6	Confident	85.7	Confident	12 Å²	12	10.3 Å²	10.3	6%	0.063	5%	0.053	C	C	.	.	H	α-helix	trans	-73.9	-33.6	177.9	-69.1	-167.4	0	0	0	111.7	I229 A233 G299 E300 S301 A306 V307 L401	I229-L303 HydrophobicContact CG2-CD1 3.81Å; I229-L303 HydrophobicContact CG2-CG 4.36Å; A233-L303 HydrophobicContact CB-CB 3.44Å; A233-L303 VanDerWaalsContact CB-CB 3.44Å; A233-L303 HydrophobicContact CB-CD1 4.29Å; A233-L303 HydrophobicContact CB-CG 4.47Å; G299-L303 PolarHBondContact O-N 2.93Å; E300-L303 PolarHBondContact O-N 3.08Å; S301-L303 PolarHBondContact O-N 2.84Å; L303-A306 PolarHBondContact O-N 2.6Å; L303-V307 WeakPolarHBondContact O-CB 3.12Å; L303-V307 VanDerWaalsContact O-CG2 3.26Å; L303-V307 WeakPolarHBondContact O-CG2 3.35Å; L303-V307 PolarHBondContact O-N 3.39Å; L303-L401 HydrophobicContact CD2-CD2 3.89Å; L303-L401 HydrophobicContact CD2-CG 4.45Å
304	N	90.4	Very high	85.9	Confident	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-61	-45.4	179.6	176.4	0.6	0	0	0	111.4	T237 S273 A274 V275 E300 S301 A306 V307 S308	T237-N304 HydrophobicContact CG2-CB 3.67Å; T237-N304 WeakPolarHBondContact CG2-OD1 3.42Å; S273-N304 PolarHBondContact O-ND2 2.86Å; S273-N304 PolarHBondContact O-OD1 3.29Å; S273-N304 VanDerWaalsContact O-OD1 3.13Å; A274-N304 WeakPolarHBondContact CA-OD1 3.44Å; V275-N304 WeakPolarHBondContact CG2-ND2 3.48Å; V275-N304 PolarHBondContact N-ND2 3Å; E300-N304 WeakPolarHBondContact O-CA 3.31Å; E300-N304 WeakPolarHBondContact O-CB 3.39Å; E300-N304 PolarHBondContact O-N 2.71Å; E300-N304 PolarHBondContact OE1-ND2 3.03Å; S301-N304 WeakPolarHBondContact O-CB 3.47Å; S301-N304 PolarHBondContact O-N 3.31Å; S301-N304 VanDerWaalsContact O-N 3.15Å; N304-A306 VanDerWaalsContact C-N 3.34Å; N304-A306 PolarHBondContact O-N 2.92Å; N304-V307 PolarHBondContact O-N 2.91Å; N304-V307 VanDerWaalsContact O-N 3.17Å; N304-S308 VanDerWaalsContact O-CB 3.28Å; N304-S308 WeakPolarHBondContact O-CB 3.19Å; N304-S308 PolarHBondContact O-N 3.42Å; N304-S308 PolarHBondContact O-OG 3.39Å; N304-S308 PolarHBondContact OD1-OG 3.16Å
305	D	88.3	Confident	86	Confident	16 Å²	16	9.6 Å²	9.6	9%	0.086	5%	0.05	C	C	.	.	H	α-helix	trans	-56.8	-47.6	179.4	-71.1	-24.4	0	0	0	111.7	A274 S301 I309 I505	A274-D305 VanDerWaalsContact CB-OD1 3.28Å; A274-D305 WeakPolarHBondContact CB-OD1 3.46Å; S301-D305 PolarHBondContact O-N 3.06Å; D305-I309 VanDerWaalsContact O-CD1 3.3Å; D305-I309 WeakPolarHBondContact O-CD1 3.21Å; D305-I309 VanDerWaalsContact O-CG1 3.27Å; D305-I309 WeakPolarHBondContact O-CG1 3.32Å; D305-I309 PolarHBondContact O-N 3.34Å; D305-I505 HydrophobicContact CB-CD1 3.93Å; D305-I505 WeakPolarHBondContact OD2-CD1 3.48Å
306	A	87.2	Confident	85.9	Confident	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-67.8	-38.6	176.8	0	0	0	0	0	112.9	L303 N304 V310 M398 L401	L303-A306 PolarHBondContact O-N 2.6Å; N304-A306 VanDerWaalsContact C-N 3.34Å; N304-A306 PolarHBondContact O-N 2.92Å; A306-V310 WeakPolarHBondContact O-CG2 3.15Å; A306-V310 PolarHBondContact O-N 3.25Å; A306-V310 VanDerWaalsContact O-N 3.09Å; A306-M398 HydrophobicContact CB-CB 4.35Å; A306-M398 HydrophobicContact CB-CE 4.13Å; A306-M398 HydrophobicContact CB-SD 3.59Å; A306-M398 VanDerWaalsContact CB-SD 3.59Å; A306-L401 HydrophobicContact CB-CD2 3.68Å
307	V	90.6	Very high	85.2	Confident	1 Å²	1	11.4 Å²	11.4	1%	0.006	7%	0.065	C	C	.	.	H	α-helix	trans	-65.6	-44.4	176.3	168	0	0	0	0	111.8	V234 T237 L303 N304 I309 V310 L311 F340 F344 M398	V234-V307 HydrophobicContact CG2-CG2 4.08Å; T237-V307 WeakPolarHBondContact OG1-CG1 3.37Å; L303-V307 WeakPolarHBondContact O-CB 3.12Å; L303-V307 VanDerWaalsContact O-CG2 3.26Å; L303-V307 WeakPolarHBondContact O-CG2 3.35Å; L303-V307 PolarHBondContact O-N 3.39Å; N304-V307 PolarHBondContact O-N 2.91Å; N304-V307 VanDerWaalsContact O-N 3.17Å; V307-I309 VanDerWaalsContact C-N 3.31Å; V307-I309 PolarHBondContact O-N 3.45Å; V307-V310 PolarHBondContact O-N 2.94Å; V307-L311 WeakPolarHBondContact O-CB 3.38Å; V307-L311 PolarHBondContact O-N 2.85Å; V307-F340 HydrophobicContact CG1-CE2 4.23Å; V307-F340 HydrophobicContact CG1-CZ 4.08Å; V307-F344 HydrophobicContact CG2-CD2 4.11Å; V307-F344 HydrophobicContact CG2-CE2 3.74Å; V307-M398 HydrophobicContact CG2-CE 3.91Å
308	S	90.1	Very high	84.2	Confident	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-64.1	-35.7	-179.7	-72.5	0	0	0	0	111.7	S270 A274 N304 T312	S270-S308 WeakPolarHBondContact O-CB 3.42Å; A274-S308 PolarHBondContact N-OG 3.03Å; N304-S308 VanDerWaalsContact O-CB 3.28Å; N304-S308 WeakPolarHBondContact O-CB 3.19Å; N304-S308 PolarHBondContact O-N 3.42Å; N304-S308 PolarHBondContact O-OG 3.39Å; N304-S308 PolarHBondContact OD1-OG 3.16Å; S308-T312 WeakPolarHBondContact O-CB 3.3Å; S308-T312 PolarHBondContact O-N 2.88Å; S308-T312 PolarHBondContact O-OG1 2.94Å
309	I	86.9	Confident	83.2	Confident	3 Å²	3	13.1 Å²	13.1	2%	0.015	7%	0.072	C	C	.	.	H	α-helix	trans	-66.7	-47.6	171.1	-63.3	157.7	0	0	0	111	L206 D305 V307 L311 T312 N313 I397 I505 L509	L206-I309 HydrophobicContact CD1-CD1 4.22Å; D305-I309 VanDerWaalsContact O-CD1 3.3Å; D305-I309 WeakPolarHBondContact O-CD1 3.21Å; D305-I309 VanDerWaalsContact O-CG1 3.27Å; D305-I309 WeakPolarHBondContact O-CG1 3.32Å; D305-I309 PolarHBondContact O-N 3.34Å; V307-I309 VanDerWaalsContact C-N 3.31Å; V307-I309 PolarHBondContact O-N 3.45Å; I309-L311 VanDerWaalsContact C-N 3.27Å; I309-L311 PolarHBondContact O-N 3.37Å; I309-T312 PolarHBondContact O-N 3.35Å; I309-N313 PolarHBondContact O-N 3.38Å; I309-N313 PolarHBondContact O-OD1 2.83Å; I309-I397 HydrophobicContact CD1-CD1 3.88Å; I309-I397 HydrophobicContact CD1-CG2 3.96Å; I309-I397 HydrophobicContact CG2-CD1 4.16Å; I309-I505 HydrophobicContact CD1-CG2 4.07Å; I309-I505 HydrophobicContact CG1-CG2 4.41Å; I309-L509 HydrophobicContact CB-CD2 4.45Å; I309-L509 HydrophobicContact CG1-CD2 3.88Å
310	V	88.6	Confident	82	Confident	1 Å²	1	17.5 Å²	17.5	1%	0.006	10%	0.103	C	C	.	.	H	α-helix	trans	-60.3	-37.4	176.9	171.4	0	0	0	0	112	A306 V307 T314 F340 M343 M398	A306-V310 WeakPolarHBondContact O-CG2 3.15Å; A306-V310 PolarHBondContact O-N 3.25Å; A306-V310 VanDerWaalsContact O-N 3.09Å; V307-V310 PolarHBondContact O-N 2.94Å; V310-T314 WeakPolarHBondContact O-CB 3.28Å; V310-T314 PolarHBondContact O-N 3.49Å; V310-T314 PolarHBondContact O-OG1 3.43Å; V310-F340 HydrophobicContact CG1-CD2 3.87Å; V310-F340 HydrophobicContact CG1-CE2 3.96Å; V310-M343 HydrophobicContact CG1-CB 3.73Å; V310-M398 HydrophobicContact CG2-CB 4.25Å
311	L	89	Confident	80.5	Confident	24 Å²	24	26.8 Å²	26.8	13%	0.126	14%	0.138	C	C	.	.	H	α-helix	trans	-71.3	-38.7	178	-165.6	67.7	0	0	0	112	A241 S270 V307 I309 T314 A315 F340	A241-L311 HydrophobicContact CB-CD2 3.58Å; S270-L311 WeakPolarHBondContact OG-CD2 3.49Å; S270-L311 WeakPolarHBondContact OG-CG 3.43Å; V307-L311 WeakPolarHBondContact O-CB 3.38Å; V307-L311 PolarHBondContact O-N 2.85Å; I309-L311 VanDerWaalsContact C-N 3.27Å; I309-L311 PolarHBondContact O-N 3.37Å; L311-T314 WeakPolarHBondContact O-CB 3.25Å; L311-T314 PolarHBondContact O-N 2.96Å; L311-A315 PolarHBondContact O-N 3.42Å; L311-F340 HydrophobicContact CB-CD2 4.47Å; L311-F340 HydrophobicContact CB-CE2 4.24Å; L311-F340 HydrophobicContact CD1-CD2 3.77Å; L311-F340 HydrophobicContact CD1-CE2 3.97Å
312	T	87.3	Confident	79	Confident	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64.4	-48.2	174	-54.5	0	0	0	0	111.1	A267 S270 L271 S308 I309 T314 A315 E316 L509 L513	A267-T312 HydrophobicContact CB-CG2 4.46Å; S270-T312 WeakPolarHBondContact CB-OG1 3.31Å; L271-T312 HydrophobicContact CB-CG2 4.34Å; L271-T312 PolarHBondContact N-OG1 2.73Å; S308-T312 WeakPolarHBondContact O-CB 3.3Å; S308-T312 PolarHBondContact O-N 2.88Å; S308-T312 PolarHBondContact O-OG1 2.94Å; I309-T312 PolarHBondContact O-N 3.35Å; T312-T314 PolarHBondContact O-N 3.32Å; T312-A315 WeakPolarHBondContact O-CB 3.3Å; T312-A315 PolarHBondContact O-N 3.47Å; T312-E316 PolarHBondContact O-N 2.99Å; T312-L509 HydrophobicContact CG2-CD1 4.26Å; T312-L509 HydrophobicContact CG2-CD2 4.09Å; T312-L509 HydrophobicContact CG2-CG 4.12Å; T312-L513 HydrophobicContact CG2-CD1 3.43Å; T312-L513 VanDerWaalsContact CG2-CD1 3.43Å
313	N	82.6	Confident	77.4	Confident	50 Å²	50	35.3 Å²	35.3	27%	0.267	19%	0.186	S	C	.	.	H	α-helix	trans	-63.6	-28.7	176.1	-66.5	20.3	0	0	0	111.9	I309 G317	I309-N313 PolarHBondContact O-N 3.38Å; I309-N313 PolarHBondContact O-OD1 2.83Å; N313-G317 PolarHBondContact O-N 3.07Å
314	T	83.9	Confident	75.4	Confident	8 Å²	8	42.2 Å²	42.2	5%	0.049	22%	0.223	C	C	.	.	H	α-helix	trans	-68.3	-43.4	171	-61.2	0	0	0	0	111.4	V310 L311 T312 F318 Y339 F340	V310-T314 WeakPolarHBondContact O-CB 3.28Å; V310-T314 PolarHBondContact O-N 3.49Å; V310-T314 PolarHBondContact O-OG1 3.43Å; L311-T314 WeakPolarHBondContact O-CB 3.25Å; L311-T314 PolarHBondContact O-N 2.96Å; T312-T314 PolarHBondContact O-N 3.32Å; T314-F318 WeakPolarHBondContact O-CB 3.31Å; T314-F318 PolarHBondContact O-N 2.85Å; T314-F318 VanDerWaalsContact O-N 3.1Å; T314-Y339 HydrophobicContact CG2-CD1 3.79Å; T314-Y339 WeakPolarHBondContact OG1-CD1 3.28Å; T314-F340 HydrophobicContact CG2-CB 4.29Å
315	A	81.6	Confident	73.5	Confident	7 Å²	7	45 Å²	45	6%	0.058	25%	0.247	C	C	.	.	H	α-helix	trans	-62.2	-45.8	177.2	0	0	0	0	0	111.9	T263 A267 L311 T312 F319	T263-A315 WeakPolarHBondContact CG2-O 3.48Å; A267-A315 HydrophobicContact CB-CB 3.96Å; L311-A315 PolarHBondContact O-N 3.42Å; T312-A315 WeakPolarHBondContact O-CB 3.3Å; T312-A315 PolarHBondContact O-N 3.47Å; A315-F319 VanDerWaalsContact O-CD2 3.25Å; A315-F319 WeakPolarHBondContact O-CD2 3.2Å; A315-F319 PolarHBondContact O-N 3.1Å
316	E	76.8	Confident	71.5	Confident	39 Å²	39	54 Å²	54	18%	0.182	29%	0.291	C	S	.	.	H	α-helix	trans	-68.9	-53.4	176	-65.4	-172	126.5	0	0	112.2	T312 F318 S320 L513 G514	T312-E316 PolarHBondContact O-N 2.99Å; E316-F318 VanDerWaalsContact C-N 3.31Å; E316-F318 PolarHBondContact O-N 2.8Å; E316-S320 WeakPolarHBondContact O-CB 3.4Å; E316-S320 PolarHBondContact O-N 3.23Å; E316-S320 PolarHBondContact O-OG 3.18Å; E316-S320 VanDerWaalsContact O-OG 3.13Å; E316-L513 HydrophobicContact CG-CD1 4.3Å; E316-L513 WeakPolarHBondContact OE1-CA 3.29Å; E316-L513 WeakPolarHBondContact OE1-CD1 3.35Å; E316-L513 WeakPolarHBondContact OE1-CG 3.49Å; E316-G514 PolarHBondContact OE1-N 3.44Å
317	G	69.4	Low	70.1	Confident	25 Å²	25	56.9 Å²	56.9	26%	0.258	31%	0.308	S	S	.	.	H	α-helix	trans	-71.3	-20.1	-169.5	0	0	0	0	0	115.5	N313	N313-G317 PolarHBondContact O-N 3.07Å
318	F	64.1	Low	69	Low	28 Å²	28	61.4 Å²	61.4	12%	0.123	34%	0.336	C	S	.	.	H	α-helix	trans	-90.1	-50.6	176.3	-174.6	-104.1	0	0	0	112.4	T314 E316 R321 T332 Q335 A336	T314-F318 WeakPolarHBondContact O-CB 3.31Å; T314-F318 PolarHBondContact O-N 2.85Å; T314-F318 VanDerWaalsContact O-N 3.1Å; E316-F318 VanDerWaalsContact C-N 3.31Å; E316-F318 PolarHBondContact O-N 2.8Å; F318-R321 WeakPolarHBondContact O-CB 3.26Å; F318-R321 PolarHBondContact O-N 3.13Å; F318-R321 VanDerWaalsContact O-N 3.17Å; F318-T332 WeakPolarHBondContact CE1-O 3.29Å; F318-T332 WeakPolarHBondContact CZ-O 3.44Å; F318-Q335 HydrophobicContact CE2-CB 3.5Å; F318-Q335 HydrophobicContact CZ-CB 3.62Å; F318-A336 HydrophobicContact CD1-CB 3.89Å; F318-A336 HydrophobicContact CE1-CB 4.12Å; F318-A336 HydrophobicContact CG-CB 4.19Å
319	F	60.1	Low	68	Low	52 Å²	52	64.3 Å²	64.3	23%	0.228	37%	0.366	C	S	.	.	H	α-helix	trans	-73	-34.1	-172.4	-74.5	-100.7	0	0	0	112.7	T263 A315 R321 S322	T263-F319 HydrophobicContact CG2-CB 3.5Å; T263-F319 HydrophobicContact CG2-CD2 4.44Å; T263-F319 HydrophobicContact CG2-CG 4.03Å; T263-F319 WeakPolarHBondContact OG1-CB 3.34Å; T263-F319 WeakPolarHBondContact OG1-CD1 3.25Å; T263-F319 WeakPolarHBondContact OG1-CG 3.41Å; A315-F319 VanDerWaalsContact O-CD2 3.25Å; A315-F319 WeakPolarHBondContact O-CD2 3.2Å; A315-F319 PolarHBondContact O-N 3.1Å; F319-R321 PolarHBondContact O-N 3.22Å; F319-S322 WeakPolarHBondContact O-CB 3.4Å; F319-S322 PolarHBondContact O-N 3.35Å
320	S	58.8	Low	67.5	Low	93 Å²	93	72.4 Å²	72.4	65%	0.65	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	-3.1	172.3	-57.5	0	0	0	0	114.2	E316	E316-S320 WeakPolarHBondContact O-CB 3.4Å; E316-S320 PolarHBondContact O-N 3.23Å; E316-S320 PolarHBondContact O-OG 3.18Å; E316-S320 VanDerWaalsContact O-OG 3.13Å
321	R	56.5	Low	67.1	Low	198 Å²	198	75.7 Å²	75.7	75%	0.747	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.1	-12.7	167.5	-84.6	-175.7	165.2	107.2	-3.6	113.7	F318 F319	F318-R321 WeakPolarHBondContact O-CB 3.26Å; F318-R321 PolarHBondContact O-N 3.13Å; F318-R321 VanDerWaalsContact O-N 3.17Å; F319-R321 PolarHBondContact O-N 3.22Å
322	S	53.6	Low	66.5	Low	39 Å²	39	75.9 Å²	75.9	27%	0.273	42%	0.416	S	S	.	.	G	3₁₀ helix	trans	-83.1	-12.7	-167.6	-164.7	0	0	0	0	114.5	F319 N324 A325	F319-S322 WeakPolarHBondContact O-CB 3.4Å; F319-S322 PolarHBondContact O-N 3.35Å; S322-N324 PolarHBondContact O-N 3.34Å; S322-A325 PolarHBondContact O-N 3.1Å
323	D	52.1	Low	66.2	Low	145 Å²	145	80.2 Å²	80.2	78%	0.775	44%	0.435	S	S	*	.	G	3₁₀ helix	trans	-61.8	-10.6	-174.7	-70	-27.8	0	0	0	115.1
324	N	46.6	Very low	66.3	Low	157 Å²	157	81.1 Å²	81.1	84%	0.84	44%	0.442	S	S	*	.	G	3₁₀ helix	trans	-111	7.9	-171.5	-71.2	-81.7	0	0	0	115.1	S322	S322-N324 PolarHBondContact O-N 3.34Å
325	A	48.5	Very low	66.2	Low	60 Å²	60	85.5 Å²	85.5	50%	0.496	46%	0.462	S	S	.	.			trans	-145.8	132.1	-179.7	0	0	0	0	0	114	S322 V327	S322-A325 PolarHBondContact O-N 3.1Å; A325-V327 HydrophobicContact CB-CG2 3.62Å; A325-V327 PolarHBondContact O-N 3.02Å
326	M	47.4	Very low	66.1	Low	205 Å²	205	86 Å²	86	100%	1.01	47%	0.466	S	S	*	.			trans	-77.4	64.7	176.5	-169.1	178.8	-177.5	0	0	110.9
327	V	57.6	Low	66.5	Low	60 Å²	60	87.9 Å²	87.9	36%	0.364	48%	0.477	S	S	.	.			trans	-90.7	138.9	-175.1	179.4	0	0	0	0	110.6	A325 D331 T332	A325-V327 HydrophobicContact CB-CG2 3.62Å; A325-V327 PolarHBondContact O-N 3.02Å; V327-D331 HydrophobicContact CG1-CB 3.61Å; V327-T332 HydrophobicContact CB-CG2 3.96Å; V327-T332 HydrophobicContact CG1-CG2 3.69Å
328	T	67.1	Low	67.3	Low	95 Å²	95	88.6 Å²	88.6	58%	0.583	48%	0.484	S	S	*	.			trans	-62.7	141.4	177.6	-14.6	0	0	0	0	111.2	W330 D331 T332	T328-W330 PolarHBondContact O-N 3.32Å; T328-D331 WeakPolarHBondContact CB-OD2 3.39Å; T328-D331 PolarHBondContact O-N 2.7Å; T328-D331 PolarHBondContact OG1-OD2 3.45Å; T328-T332 PolarHBondContact O-N 3.23Å
329	G	69.6	Low	68.3	Low	61 Å²	61	90.6 Å²	90.6	63%	0.629	49%	0.491	S	S	*	.	H	α-helix	trans	-60.2	-13.8	-177.6	0	0	0	0	0	115.9	T332	G329-T332 WeakPolarHBondContact CA-OG1 3.49Å; G329-T332 PolarHBondContact O-OG1 3.23Å
330	W	76.8	Confident	69.6	Low	174 Å²	174	89 Å²	89	66%	0.659	48%	0.484	S	S	*	.	H	α-helix	trans	-78.7	-44.8	169.9	179.7	-102	0	0	0	112.2	T328 T332 F333 V334	T328-W330 PolarHBondContact O-N 3.32Å; W330-T332 VanDerWaalsContact C-N 3.31Å; W330-T332 PolarHBondContact O-N 2.87Å; W330-F333 WeakPolarHBondContact O-CB 3.35Å; W330-F333 PolarHBondContact O-N 3.26Å; W330-V334 HydrophobicContact CD2-CG2 4.42Å; W330-V334 HydrophobicContact CZ2-CG2 4.23Å; W330-V334 WeakPolarHBondContact O-CG2 3.31Å; W330-V334 PolarHBondContact O-N 2.75Å
331	D	79.8	Confident	71.1	Confident	69 Å²	69	88.1 Å²	88.1	37%	0.369	47%	0.472	S	S	.	.	H	α-helix	trans	-70.4	-31	-177.2	-52.1	-50.1	0	0	0	111.2	V327 T328 Q335	V327-D331 HydrophobicContact CG1-CB 3.61Å; T328-D331 WeakPolarHBondContact CB-OD2 3.39Å; T328-D331 PolarHBondContact O-N 2.7Å; T328-D331 PolarHBondContact OG1-OD2 3.45Å; D331-Q335 WeakPolarHBondContact O-CB 3.48Å; D331-Q335 VanDerWaalsContact O-CG 3.24Å; D331-Q335 WeakPolarHBondContact O-CG 3.32Å; D331-Q335 PolarHBondContact O-N 3.35Å; D331-Q335 PolarHBondContact O-NE2 3.12Å
332	T	76.6	Confident	72.7	Confident	28 Å²	28	85.2 Å²	85.2	17%	0.172	47%	0.465	C	S	.	.	H	α-helix	trans	-66.5	-43.3	170.2	56	0	0	0	0	111.7	F318 V327 T328 G329 W330 Q335 A336	F318-T332 WeakPolarHBondContact CE1-O 3.29Å; F318-T332 WeakPolarHBondContact CZ-O 3.44Å; V327-T332 HydrophobicContact CB-CG2 3.96Å; V327-T332 HydrophobicContact CG1-CG2 3.69Å; T328-T332 PolarHBondContact O-N 3.23Å; G329-T332 WeakPolarHBondContact CA-OG1 3.49Å; G329-T332 PolarHBondContact O-OG1 3.23Å; W330-T332 VanDerWaalsContact C-N 3.31Å; W330-T332 PolarHBondContact O-N 2.87Å; T332-Q335 PolarHBondContact O-N 3.12Å; T332-A336 WeakPolarHBondContact O-CB 3.14Å; T332-A336 PolarHBondContact O-N 2.84Å
333	F	80.5	Confident	74.3	Confident	91 Å²	91	83.8 Å²	83.8	40%	0.399	45%	0.454	S	S	.	.	H	α-helix	trans	-62.1	-45.2	175.2	176.4	-96.2	0	0	0	112.3	F242 W330 Q335 A336 L337	F242-F333 AromaticContact CZ-CE2 3.98Å; F242-F333 HydrophobicContact CZ-CE2 3.98Å; W330-F333 WeakPolarHBondContact O-CB 3.35Å; W330-F333 PolarHBondContact O-N 3.26Å; F333-Q335 VanDerWaalsContact C-N 3.34Å; F333-Q335 PolarHBondContact O-N 2.98Å; F333-A336 PolarHBondContact O-N 2.85Å; F333-L337 HydrophobicContact CE1-CD2 4.36Å; F333-L337 WeakPolarHBondContact O-CB 3.28Å; F333-L337 PolarHBondContact O-N 3.38Å
334	V	84.5	Confident	76	Confident	69 Å²	69	77.8 Å²	77.8	42%	0.418	42%	0.421	S	S	.	.	H	α-helix	trans	-63.2	-39.2	177.6	172.1	0	0	0	0	111.5	W330 G338	W330-V334 HydrophobicContact CD2-CG2 4.42Å; W330-V334 HydrophobicContact CZ2-CG2 4.23Å; W330-V334 WeakPolarHBondContact O-CG2 3.31Å; W330-V334 PolarHBondContact O-N 2.75Å; V334-G338 PolarHBondContact O-N 3.1Å
335	Q	81.8	Confident	78.1	Confident	100 Å²	100	76.5 Å²	76.5	47%	0.467	41%	0.408	S	S	.	.	H	α-helix	trans	-69.1	-42.1	175.3	-74.4	170.5	80.3	0	0	112.8	F318 D331 T332 F333 G338 Y339	F318-Q335 HydrophobicContact CE2-CB 3.5Å; F318-Q335 HydrophobicContact CZ-CB 3.62Å; D331-Q335 WeakPolarHBondContact O-CB 3.48Å; D331-Q335 VanDerWaalsContact O-CG 3.24Å; D331-Q335 WeakPolarHBondContact O-CG 3.32Å; D331-Q335 PolarHBondContact O-N 3.35Å; D331-Q335 PolarHBondContact O-NE2 3.12Å; T332-Q335 PolarHBondContact O-N 3.12Å; F333-Q335 VanDerWaalsContact C-N 3.34Å; F333-Q335 PolarHBondContact O-N 2.98Å; Q335-G338 PolarHBondContact O-N 3.08Å; Q335-Y339 PolarHBondContact O-N 3.32Å
336	A	80.4	Confident	80.2	Confident	18 Å²	18	74.7 Å²	74.7	15%	0.149	40%	0.396	C	S	.	.	H	α-helix	trans	-62.4	-42.6	175.5	0	0	0	0	0	111.6	F318 T332 F333 Y339 F340	F318-A336 HydrophobicContact CD1-CB 3.89Å; F318-A336 HydrophobicContact CE1-CB 4.12Å; F318-A336 HydrophobicContact CG-CB 4.19Å; T332-A336 WeakPolarHBondContact O-CB 3.14Å; T332-A336 PolarHBondContact O-N 2.84Å; F333-A336 PolarHBondContact O-N 2.85Å; A336-Y339 PolarHBondContact O-N 3.1Å; A336-F340 WeakPolarHBondContact O-CB 3.48Å; A336-F340 PolarHBondContact O-N 3.39Å
337	L	85.3	Confident	82.4	Confident	79 Å²	79	65 Å²	65	41%	0.414	35%	0.348	S	S	.	.	H	α-helix	trans	-62.3	-43.4	172.6	179.3	60.5	0	0	0	111.5	F333 Y339 F340 L341	F333-L337 HydrophobicContact CE1-CD2 4.36Å; F333-L337 WeakPolarHBondContact O-CB 3.28Å; F333-L337 PolarHBondContact O-N 3.38Å; L337-Y339 VanDerWaalsContact C-N 3.34Å; L337-Y339 PolarHBondContact O-N 3.46Å; L337-F340 PolarHBondContact O-N 3.46Å; L337-L341 HydrophobicContact CD1-CD1 4.05Å; L337-L341 HydrophobicContact CD1-CG 4.14Å; L337-L341 HydrophobicContact CG-CD1 3.9Å; L337-L341 HydrophobicContact CG-CG 4.43Å; L337-L341 WeakPolarHBondContact O-CB 3.38Å; L337-L341 WeakPolarHBondContact O-CG 3.34Å; L337-L341 PolarHBondContact O-N 3.05Å
338	G	86.6	Confident	84	Confident	39 Å²	39	62.5 Å²	62.5	40%	0.402	33%	0.334	S	S	.	.	H	α-helix	trans	-61.1	-39.4	174.7	0	0	0	0	0	113.3	V334 Q335 K342	V334-G338 PolarHBondContact O-N 3.1Å; Q335-G338 PolarHBondContact O-N 3.08Å; G338-K342 WeakPolarHBondContact O-CB 3.48Å; G338-K342 PolarHBondContact O-N 2.82Å
339	Y	85.1	Confident	85.3	Confident	70 Å²	70	60.9 Å²	60.9	28%	0.275	33%	0.33	S	S	.	.	H	α-helix	trans	-67.3	-47.8	174.3	-176.8	-89.6	0	0	0	111.6	T314 Q335 A336 L337 L341 K342 M343	T314-Y339 HydrophobicContact CG2-CD1 3.79Å; T314-Y339 WeakPolarHBondContact OG1-CD1 3.28Å; Q335-Y339 PolarHBondContact O-N 3.32Å; A336-Y339 PolarHBondContact O-N 3.1Å; L337-Y339 VanDerWaalsContact C-N 3.34Å; L337-Y339 PolarHBondContact O-N 3.46Å; Y339-L341 PolarHBondContact O-N 2.88Å; Y339-K342 WeakPolarHBondContact O-CB 3.36Å; Y339-K342 PolarHBondContact O-N 2.79Å; Y339-M343 HydrophobicContact CD1-CG 3.88Å; Y339-M343 HydrophobicContact CE1-CG 3.48Å; Y339-M343 VanDerWaalsContact CE1-CG 3.48Å; Y339-M343 HydrophobicContact CE1-SD 4.27Å; Y339-M343 HydrophobicContact CE2-CG 4.28Å; Y339-M343 HydrophobicContact CE2-SD 4.34Å; Y339-M343 HydrophobicContact CG-CG 4.46Å; Y339-M343 WeakPolarHBondContact O-CG 3.37Å; Y339-M343 PolarHBondContact O-N 3.04Å
340	F	86.9	Confident	86.5	Confident	19 Å²	19	59.6 Å²	59.6	8%	0.083	31%	0.309	C	S	.	.	H	α-helix	trans	-55.4	-49.4	175.1	174.4	-96.7	0	0	0	111.6	V234 V307 V310 L311 T314 A336 L337 K342 M343 F344	V234-F340 HydrophobicContact CG1-CE1 4.22Å; V234-F340 HydrophobicContact CG1-CZ 4.25Å; V307-F340 HydrophobicContact CG1-CE2 4.23Å; V307-F340 HydrophobicContact CG1-CZ 4.08Å; V310-F340 HydrophobicContact CG1-CD2 3.87Å; V310-F340 HydrophobicContact CG1-CE2 3.96Å; L311-F340 HydrophobicContact CB-CD2 4.47Å; L311-F340 HydrophobicContact CB-CE2 4.24Å; L311-F340 HydrophobicContact CD1-CD2 3.77Å; L311-F340 HydrophobicContact CD1-CE2 3.97Å; T314-F340 HydrophobicContact CG2-CB 4.29Å; A336-F340 WeakPolarHBondContact O-CB 3.48Å; A336-F340 PolarHBondContact O-N 3.39Å; L337-F340 PolarHBondContact O-N 3.46Å; F340-K342 PolarHBondContact O-N 3.26Å; F340-M343 PolarHBondContact O-N 2.88Å; F340-F344 HydrophobicContact CZ-CD2 4.32Å; F340-F344 VanDerWaalsContact O-CB 3.26Å; F340-F344 WeakPolarHBondContact O-CB 3.3Å; F340-F344 PolarHBondContact O-N 3Å
341	L	89.5	Confident	87.4	Confident	74 Å²	74	51.3 Å²	51.3	39%	0.387	28%	0.277	S	S	.	.	H	α-helix	trans	-61.6	-41.7	178	-69.4	167.5	0	0	0	111.7	L337 Y339 F345	L337-L341 HydrophobicContact CD1-CD1 4.05Å; L337-L341 HydrophobicContact CD1-CG 4.14Å; L337-L341 HydrophobicContact CG-CD1 3.9Å; L337-L341 HydrophobicContact CG-CG 4.43Å; L337-L341 WeakPolarHBondContact O-CB 3.38Å; L337-L341 WeakPolarHBondContact O-CG 3.34Å; L337-L341 PolarHBondContact O-N 3.05Å; Y339-L341 PolarHBondContact O-N 2.88Å; L341-F345 HydrophobicContact CB-CD2 4.49Å; L341-F345 HydrophobicContact CD2-CD2 4.28Å; L341-F345 HydrophobicContact CD2-CE2 3.85Å; L341-F345 WeakPolarHBondContact O-CB 3.41Å; L341-F345 WeakPolarHBondContact O-CD2 3.31Å; L341-F345 PolarHBondContact O-N 2.9Å
342	K	89.6	Confident	88	Confident	138 Å²	138	50.2 Å²	50.2	60%	0.6	27%	0.273	S	S	*	.	H	α-helix	trans	-60.8	-46.8	174.7	-177.5	-165.8	171.2	-164.2	0	111.6	G338 Y339 F340 G346	G338-K342 WeakPolarHBondContact O-CB 3.48Å; G338-K342 PolarHBondContact O-N 2.82Å; Y339-K342 WeakPolarHBondContact O-CB 3.36Å; Y339-K342 PolarHBondContact O-N 2.79Å; F340-K342 PolarHBondContact O-N 3.26Å; K342-G346 VanDerWaalsContact O-CA 3.29Å; K342-G346 WeakPolarHBondContact O-CA 3.16Å; K342-G346 PolarHBondContact O-N 2.85Å
343	M	87.6	Confident	88.9	Confident	9 Å²	9	53.5 Å²	53.5	4%	0.044	29%	0.289	C	S	.	.	H	α-helix	trans	-66.8	-47.3	-179.5	-67.5	-62.1	-78.9	0	0	111.3	V310 Y339 F340 S347 Q393 L394	V310-M343 HydrophobicContact CG1-CB 3.73Å; Y339-M343 HydrophobicContact CD1-CG 3.88Å; Y339-M343 HydrophobicContact CE1-CG 3.48Å; Y339-M343 VanDerWaalsContact CE1-CG 3.48Å; Y339-M343 HydrophobicContact CE1-SD 4.27Å; Y339-M343 HydrophobicContact CE2-CG 4.28Å; Y339-M343 HydrophobicContact CE2-SD 4.34Å; Y339-M343 HydrophobicContact CG-CG 4.46Å; Y339-M343 WeakPolarHBondContact O-CG 3.37Å; Y339-M343 PolarHBondContact O-N 3.04Å; F340-M343 PolarHBondContact O-N 2.88Å; M343-S347 WeakPolarHBondContact O-CB 3.43Å; M343-S347 PolarHBondContact O-N 3.35Å; M343-S347 PolarHBondContact O-OG 3.38Å; M343-Q393 WeakPolarHBondContact CE-O 3.28Å; M343-L394 HydrophobicContact SD-CD2 4.1Å
344	F	88.3	Confident	89.6	Confident	19 Å²	19	49.5 Å²	49.5	8%	0.083	27%	0.272	C	S	.	.	H	α-helix	trans	-60	-58.8	179	-179.6	-86.8	0	0	0	111.7	V234 V307 F340 A348 M398	V234-F344 HydrophobicContact CG2-CE2 3.76Å; V234-F344 HydrophobicContact CG2-CZ 3.87Å; V307-F344 HydrophobicContact CG2-CD2 4.11Å; V307-F344 HydrophobicContact CG2-CE2 3.74Å; F340-F344 HydrophobicContact CZ-CD2 4.32Å; F340-F344 VanDerWaalsContact O-CB 3.26Å; F340-F344 WeakPolarHBondContact O-CB 3.3Å; F340-F344 PolarHBondContact O-N 3Å; F344-A348 VanDerWaalsContact O-CB 3.24Å; F344-A348 WeakPolarHBondContact O-CB 3.44Å; F344-A348 PolarHBondContact O-N 2.76Å; F344-M398 HydrophobicContact CD2-CE 3.49Å; F344-M398 VanDerWaalsContact CD2-CE 3.49Å; F344-M398 HydrophobicContact CE2-CE 3.32Å; F344-M398 HydrophobicContact CG-CE 4.49Å; F344-M398 HydrophobicContact CZ-CE 4.22Å
345	F	91.2	Very high	90	Very high	129 Å²	129	46.2 Å²	46.2	57%	0.566	25%	0.252	S	S	*	.	H	α-helix	trans	-72.5	-31.5	-177.7	-74	-68.5	0	0	0	112.8	L341 A349	L341-F345 HydrophobicContact CB-CD2 4.49Å; L341-F345 HydrophobicContact CD2-CD2 4.28Å; L341-F345 HydrophobicContact CD2-CE2 3.85Å; L341-F345 WeakPolarHBondContact O-CB 3.41Å; L341-F345 WeakPolarHBondContact O-CD2 3.31Å; L341-F345 PolarHBondContact O-N 2.9Å; F345-A349 WeakPolarHBondContact O-CB 3.41Å; F345-A349 PolarHBondContact O-N 3.41Å
346	G	92.8	Very high	90.5	Very high	23 Å²	23	43.1 Å²	43.1	24%	0.237	24%	0.239	C	C	.	.	H	α-helix	trans	-63.1	-52.3	174.8	0	0	0	0	0	112.2	K342 A349 L350	K342-G346 VanDerWaalsContact O-CA 3.29Å; K342-G346 WeakPolarHBondContact O-CA 3.16Å; K342-G346 PolarHBondContact O-N 2.85Å; G346-A349 PolarHBondContact O-N 2.97Å; G346-L350 WeakPolarHBondContact O-CB 3.32Å; G346-L350 PolarHBondContact O-N 2.88Å
347	S	93.1	Very high	91.1	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-63.1	-43.4	175.3	-74.2	0	0	0	0	112.5	M343 A349 L350 G351 S395	M343-S347 WeakPolarHBondContact O-CB 3.43Å; M343-S347 PolarHBondContact O-N 3.35Å; M343-S347 PolarHBondContact O-OG 3.38Å; S347-A349 PolarHBondContact O-N 3.5Å; S347-L350 PolarHBondContact O-N 2.95Å; S347-G351 PolarHBondContact O-N 3.04Å; S347-S395 WeakPolarHBondContact CB-O 3.48Å; S347-S395 WeakPolarHBondContact OG-CA 3.45Å; S347-S395 WeakPolarHBondContact OG-CB 3.35Å; S347-S395 PolarHBondContact OG-N 3.07Å; S347-S395 PolarHBondContact OG-O 3.49Å
348	A	91.6	Very high	91.4	Very high	9 Å²	9	42.5 Å²	42.5	7%	0.074	23%	0.232	C	C	.	.	H	α-helix	trans	-62.7	-41.1	179.2	0	0	0	0	0	112.3	F344 T352 F402	F344-A348 VanDerWaalsContact O-CB 3.24Å; F344-A348 WeakPolarHBondContact O-CB 3.44Å; F344-A348 PolarHBondContact O-N 2.76Å; A348-T352 WeakPolarHBondContact O-CB 3.45Å; A348-T352 PolarHBondContact O-N 3.22Å; A348-T352 PolarHBondContact O-OG1 3.49Å; A348-F402 HydrophobicContact CB-CD1 4.21Å; A348-F402 HydrophobicContact CB-CD2 3.52Å; A348-F402 HydrophobicContact CB-CE1 4.21Å; A348-F402 HydrophobicContact CB-CE2 3.51Å; A348-F402 HydrophobicContact CB-CG 3.88Å; A348-F402 HydrophobicContact CB-CZ 3.88Å
349	A	94.3	Very high	91.6	Very high	61 Å²	61	40.6 Å²	40.6	50%	0.504	21%	0.213	S	C	.	.	H	α-helix	trans	-67.5	-41.4	175.6	0	0	0	0	0	112.2	F345 G346 S347 L353	F345-A349 WeakPolarHBondContact O-CB 3.41Å; F345-A349 PolarHBondContact O-N 3.41Å; G346-A349 PolarHBondContact O-N 2.97Å; S347-A349 PolarHBondContact O-N 3.5Å; A349-L353 VanDerWaalsContact O-CB 3.26Å; A349-L353 WeakPolarHBondContact O-CB 3.22Å; A349-L353 PolarHBondContact O-N 2.92Å
350	L	95.4	Very high	91.7	Very high	34 Å²	34	39.5 Å²	39.5	18%	0.178	21%	0.212	C	C	.	.	H	α-helix	trans	-64.7	-48.8	177.5	-174.1	68.8	0	0	0	111.6	G346 S347 T352 L353 T354 L388 A389 L394	G346-L350 WeakPolarHBondContact O-CB 3.32Å; G346-L350 PolarHBondContact O-N 2.88Å; S347-L350 PolarHBondContact O-N 2.95Å; L350-T352 PolarHBondContact O-N 3.15Å; L350-L353 PolarHBondContact O-N 2.99Å; L350-T354 PolarHBondContact O-N 3.3Å; L350-T354 PolarHBondContact O-OG1 3.34Å; L350-L388 HydrophobicContact CD2-CB 4.12Å; L350-A389 VanDerWaalsContact CD2-CA 3.49Å; L350-A389 HydrophobicContact CD2-CB 3.66Å; L350-L394 HydrophobicContact CD2-CD1 4.34Å
351	G	95	Very high	91.8	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-57.9	-48.7	176.1	0	0	0	0	0	111.9	S347 L353 T354 G355 S399 A403	S347-G351 PolarHBondContact O-N 3.04Å; G351-L353 PolarHBondContact O-N 3.49Å; G351-T354 WeakPolarHBondContact CA-OG1 3.43Å; G351-T354 PolarHBondContact O-N 2.76Å; G351-T354 PolarHBondContact O-OG1 3.11Å; G351-G355 PolarHBondContact O-N 2.94Å; G351-S399 WeakPolarHBondContact CA-O 3.4Å; G351-S399 PolarHBondContact N-OG 3.33Å; G351-A403 WeakPolarHBondContact O-CA 3.26Å; G351-A403 WeakPolarHBondContact O-CB 3.29Å
352	T	92.7	Very high	91.7	Very high	45 Å²	45	38.4 Å²	38.4	28%	0.276	20%	0.204	S	C	.	.	H	α-helix	trans	-56.2	-47.8	174.3	-61.6	0	0	0	0	111.5	A348 L350 T354 G355 L356 V406	A348-T352 WeakPolarHBondContact O-CB 3.45Å; A348-T352 PolarHBondContact O-N 3.22Å; A348-T352 PolarHBondContact O-OG1 3.49Å; L350-T352 PolarHBondContact O-N 3.15Å; T352-T354 PolarHBondContact O-N 2.92Å; T352-G355 PolarHBondContact O-N 2.85Å; T352-L356 HydrophobicContact CG2-CD1 4.08Å; T352-L356 HydrophobicContact CG2-CG 4.44Å; T352-L356 WeakPolarHBondContact O-CG 3.19Å; T352-L356 PolarHBondContact O-N 2.96Å; T352-V406 HydrophobicContact CG2-CG2 4.15Å
353	L	95.3	Very high	91.5	Very high	98 Å²	98	34.1 Å²	34.1	51%	0.513	19%	0.186	S	C	.	.	H	α-helix	trans	-61.3	-44.2	178.8	179.7	61.2	0	0	0	111.7	A349 L350 G351 G355 L356 I357	A349-L353 VanDerWaalsContact O-CB 3.26Å; A349-L353 WeakPolarHBondContact O-CB 3.22Å; A349-L353 PolarHBondContact O-N 2.92Å; L350-L353 PolarHBondContact O-N 2.99Å; G351-L353 PolarHBondContact O-N 3.49Å; L353-G355 PolarHBondContact O-N 2.89Å; L353-L356 PolarHBondContact O-N 3.22Å; L353-I357 HydrophobicContact CD1-CD1 4.08Å; L353-I357 HydrophobicContact CD1-CG1 4.37Å; L353-I357 HydrophobicContact CG-CD1 3.89Å; L353-I357 WeakPolarHBondContact O-CB 3.42Å; L353-I357 VanDerWaalsContact O-CG1 3.24Å; L353-I357 WeakPolarHBondContact O-CG1 3.35Å; L353-I357 PolarHBondContact O-N 3.45Å
354	T	94.6	Very high	91.3	Very high	7 Å²	7	40.5 Å²	40.5	4%	0.043	22%	0.215	C	C	.	.	H	α-helix	trans	-65.3	-37.6	177	52.3	0	0	0	0	113.1	L350 G351 T352 I357 S358 L388	L350-T354 PolarHBondContact O-N 3.3Å; L350-T354 PolarHBondContact O-OG1 3.34Å; G351-T354 WeakPolarHBondContact CA-OG1 3.43Å; G351-T354 PolarHBondContact O-N 2.76Å; G351-T354 PolarHBondContact O-OG1 3.11Å; T352-T354 PolarHBondContact O-N 2.92Å; T354-I357 PolarHBondContact O-N 3.49Å; T354-S358 WeakPolarHBondContact O-CB 3.42Å; T354-S358 PolarHBondContact O-N 3.42Å; T354-L388 HydrophobicContact CG2-CD1 3.78Å
355	G	93	Very high	91.1	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-66	-41.4	175	0	0	0	0	0	112.4	G351 T352 L353 S358 A359 T411	G351-G355 PolarHBondContact O-N 2.94Å; T352-G355 PolarHBondContact O-N 2.85Å; L353-G355 PolarHBondContact O-N 2.89Å; G355-S358 WeakPolarHBondContact O-CB 3.1Å; G355-S358 PolarHBondContact O-N 3.33Å; G355-A359 PolarHBondContact O-N 3.46Å; G355-T411 PolarHBondContact O-OG1 3.5Å
356	L	92	Very high	90.3	Very high	35 Å²	35	42.4 Å²	42.4	18%	0.183	23%	0.226	C	C	.	.	H	α-helix	trans	-67.2	-37.3	174.4	-67.5	178.9	0	0	0	112.3	T352 L353 A359 L360 V406 Y410 F615	T352-L356 HydrophobicContact CG2-CD1 4.08Å; T352-L356 HydrophobicContact CG2-CG 4.44Å; T352-L356 WeakPolarHBondContact O-CG 3.19Å; T352-L356 PolarHBondContact O-N 2.96Å; L353-L356 PolarHBondContact O-N 3.22Å; L356-A359 PolarHBondContact O-N 3.44Å; L356-L360 WeakPolarHBondContact O-CG 3.09Å; L356-L360 PolarHBondContact O-N 2.96Å; L356-V406 HydrophobicContact CD2-CG1 3.78Å; L356-V406 HydrophobicContact CG-CG1 3.87Å; L356-Y410 HydrophobicContact CD2-CD2 3.75Å; L356-Y410 HydrophobicContact CD2-CE2 3.85Å; L356-Y410 HydrophobicContact CD2-CG 4.3Å; L356-F615 HydrophobicContact CB-CD1 4.28Å; L356-F615 HydrophobicContact CB-CE1 3.77Å; L356-F615 HydrophobicContact CB-CZ 4.2Å; L356-F615 HydrophobicContact CD1-CE1 4.39Å; L356-F615 HydrophobicContact CD1-CE2 4.38Å; L356-F615 HydrophobicContact CD1-CZ 3.97Å; L356-F615 HydrophobicContact CD2-CD1 3.87Å; L356-F615 HydrophobicContact CD2-CD2 3.9Å; L356-F615 HydrophobicContact CD2-CE1 3.84Å; L356-F615 HydrophobicContact CD2-CE2 3.88Å; L356-F615 HydrophobicContact CD2-CG 3.92Å; L356-F615 HydrophobicContact CD2-CZ 3.86Å; L356-F615 HydrophobicContact CG-CE1 4.2Å; L356-F615 HydrophobicContact CG-CZ 4.22Å
357	I	93.3	Very high	89.7	Confident	83 Å²	83	42.8 Å²	42.8	43%	0.426	22%	0.223	S	C	.	.	H	α-helix	trans	-62.7	-43.3	172.1	-72.4	165.8	0	0	0	110.5	L353 T354 A359 L360 F361 F381	L353-I357 HydrophobicContact CD1-CD1 4.08Å; L353-I357 HydrophobicContact CD1-CG1 4.37Å; L353-I357 HydrophobicContact CG-CD1 3.89Å; L353-I357 WeakPolarHBondContact O-CB 3.42Å; L353-I357 VanDerWaalsContact O-CG1 3.24Å; L353-I357 WeakPolarHBondContact O-CG1 3.35Å; L353-I357 PolarHBondContact O-N 3.45Å; T354-I357 PolarHBondContact O-N 3.49Å; I357-A359 PolarHBondContact O-N 2.98Å; I357-L360 PolarHBondContact O-N 2.76Å; I357-F361 WeakPolarHBondContact O-CB 3.33Å; I357-F361 PolarHBondContact O-N 3.47Å; I357-F381 HydrophobicContact CG2-CE1 4.29Å
358	S	92.4	Very high	88.7	Confident	0 Å²	0	45.5 Å²	45.5	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-59.4	-45.7	175.2	-177.8	0	0	0	0	111.8	T354 G355 F361 L362 F381	T354-S358 WeakPolarHBondContact O-CB 3.42Å; T354-S358 PolarHBondContact O-N 3.42Å; G355-S358 WeakPolarHBondContact O-CB 3.1Å; G355-S358 PolarHBondContact O-N 3.33Å; S358-F361 PolarHBondContact O-N 3.47Å; S358-L362 PolarHBondContact O-N 2.95Å; S358-F381 WeakPolarHBondContact OG-CB 3.41Å; S358-F381 WeakPolarHBondContact OG-CD2 3.25Å; S358-F381 VanDerWaalsContact OG-CG 3.29Å; S358-F381 WeakPolarHBondContact OG-CG 3.35Å
359	A	89.2	Confident	88	Confident	0 Å²	0	54.3 Å²	54.3	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-60	-47.8	175.6	0	0	0	0	0	111.9	G355 L356 I357 F361 K363 T411 N414 F615	G355-A359 PolarHBondContact O-N 3.46Å; L356-A359 PolarHBondContact O-N 3.44Å; I357-A359 PolarHBondContact O-N 2.98Å; A359-F361 PolarHBondContact O-N 3.23Å; A359-K363 VanDerWaalsContact O-CB 3.3Å; A359-K363 WeakPolarHBondContact O-CB 3.43Å; A359-K363 PolarHBondContact O-N 2.79Å; A359-T411 WeakPolarHBondContact CA-OG1 3.48Å; A359-T411 WeakPolarHBondContact CB-OG1 3.42Å; A359-T411 PolarHBondContact N-OG1 2.93Å; A359-N414 PolarHBondContact O-ND2 3.11Å; A359-F615 HydrophobicContact CB-CB 4.34Å; A359-F615 HydrophobicContact CB-CD1 4.45Å
360	L	87.8	Confident	87.5	Confident	47 Å²	47	54.8 Å²	54.8	25%	0.246	27%	0.266	C	S	.	.	H	α-helix	trans	-63.4	-39.8	176.4	-70.3	179	0	0	0	112.5	L356 I357 K363 H364 F614 F615	L356-L360 WeakPolarHBondContact O-CG 3.09Å; L356-L360 PolarHBondContact O-N 2.96Å; I357-L360 PolarHBondContact O-N 2.76Å; L360-K363 PolarHBondContact O-N 3.21Å; L360-H364 PolarHBondContact O-N 2.87Å; L360-H364 VanDerWaalsContact O-N 3.11Å; L360-H364 PolarHBondContact O-ND1 2.92Å; L360-F614 HydrophobicContact CD1-CE1 4.42Å; L360-F614 HydrophobicContact CD2-CD1 4.26Å; L360-F614 HydrophobicContact CD2-CE1 3.82Å; L360-F614 HydrophobicContact CD2-CZ 4.43Å; L360-F615 HydrophobicContact CD1-CD1 4.38Å; L360-F615 HydrophobicContact CD1-CE1 3.84Å; L360-F615 HydrophobicContact CD2-CD1 3.67Å; L360-F615 HydrophobicContact CD2-CE1 3.87Å; L360-F615 HydrophobicContact CG-CD1 3.7Å; L360-F615 HydrophobicContact CG-CE1 3.68Å
361	F	90.3	Very high	86.9	Confident	63 Å²	63	54.9 Å²	54.9	28%	0.276	27%	0.269	S	S	.	.	H	α-helix	trans	-60.5	-54.2	179.1	-172.4	-83.4	0	0	0	110.5	I357 S358 A359 K363 H364 F365 L367 M377 F381	I357-F361 WeakPolarHBondContact O-CB 3.33Å; I357-F361 PolarHBondContact O-N 3.47Å; S358-F361 PolarHBondContact O-N 3.47Å; A359-F361 PolarHBondContact O-N 3.23Å; F361-K363 PolarHBondContact O-N 2.83Å; F361-H364 PolarHBondContact O-N 3.29Å; F361-H364 VanDerWaalsContact O-N 3.15Å; F361-F365 AromaticContact CD1-CD2 3.87Å; F361-F365 HydrophobicContact CD1-CD2 3.87Å; F361-F365 AromaticContact CD2-CD2 3.69Å; F361-F365 HydrophobicContact CD2-CD2 3.69Å; F361-F365 AromaticContact CD2-CE2 3.67Å; F361-F365 HydrophobicContact CD2-CE2 3.67Å; F361-F365 HydrophobicContact CE1-CB 4.24Å; F361-F365 AromaticContact CE1-CD2 3.75Å; F361-F365 HydrophobicContact CE1-CD2 3.75Å; F361-F365 HydrophobicContact CE1-CE2 4.45Å; F361-F365 HydrophobicContact CE1-CG 4.17Å; F361-F365 AromaticContact CE2-CD2 3.57Å; F361-F365 HydrophobicContact CE2-CD2 3.57Å; F361-F365 AromaticContact CE2-CE2 3.43Å; F361-F365 HydrophobicContact CE2-CE2 3.43Å; F361-F365 VanDerWaalsContact CE2-CE2 3.43Å; F361-F365 HydrophobicContact CE2-CZ 4.3Å; F361-F365 AromaticContact CG-CD2 3.84Å; F361-F365 HydrophobicContact CG-CD2 3.84Å; F361-F365 HydrophobicContact CG-CE2 4.29Å; F361-F365 AromaticContact CZ-CD2 3.6Å; F361-F365 HydrophobicContact CZ-CD2 3.6Å; F361-F365 AromaticContact CZ-CE2 3.86Å; F361-F365 HydrophobicContact CZ-CE2 3.86Å; F361-F365 HydrophobicContact CZ-CG 4.16Å; F361-F365 WeakPolarHBondContact O-CD2 3.42Å; F361-F365 PolarHBondContact O-N 3.23Å; F361-L367 HydrophobicContact CE1-CD1 4.49Å; F361-M377 HydrophobicContact CD1-CE 4.37Å; F361-M377 HydrophobicContact CE1-CE 3.8Å; F361-M377 HydrophobicContact CZ-CE 4.02Å; F361-F381 HydrophobicContact CB-CE2 4.03Å; F361-F381 HydrophobicContact CB-CZ 3.83Å; F361-F381 AromaticContact CD1-CE2 3.81Å; F361-F381 HydrophobicContact CD1-CE2 3.81Å; F361-F381 HydrophobicContact CD1-CZ 4.17Å; F361-F381 HydrophobicContact CD2-CZ 4.14Å; F361-F381 HydrophobicContact CE1-CE2 4.45Å; F361-F381 AromaticContact CG-CE2 3.89Å; F361-F381 HydrophobicContact CG-CE2 3.89Å; F361-F381 AromaticContact CG-CZ 3.78Å; F361-F381 HydrophobicContact CG-CZ 3.78Å
362	L	87.5	Confident	86.6	Confident	7 Å²	7	59.9 Å²	59.9	4%	0.037	30%	0.304	C	S	.	.	H	α-helix	trans	-69.8	-19.4	-179.7	-73.1	159.8	0	0	0	113.3	S358 L367 E374 M378 T411 N414 L415	S358-L362 PolarHBondContact O-N 2.95Å; L362-L367 HydrophobicContact CD2-CD1 4.07Å; L362-E374 HydrophobicContact CD2-CG 4.12Å; L362-M378 HydrophobicContact CD1-CG 4.13Å; L362-M378 HydrophobicContact CD1-SD 3.6Å; L362-M378 VanDerWaalsContact CD1-SD 3.6Å; L362-T411 HydrophobicContact CD1-CG2 3.42Å; L362-T411 VanDerWaalsContact CD1-CG2 3.42Å; L362-N414 HydrophobicContact CB-CB 4.34Å; L362-L415 HydrophobicContact CD1-CD2 4.01Å
363	K	84.6	Confident	86.4	Confident	48 Å²	48	62.1 Å²	62.1	21%	0.209	31%	0.314	C	S	.	.	H	α-helix	trans	-73.2	-36.2	169.6	179.2	165.3	177.7	173.6	0	113.3	A359 L360 F361 P613 F614 F615 T616 R617	A359-K363 VanDerWaalsContact O-CB 3.3Å; A359-K363 WeakPolarHBondContact O-CB 3.43Å; A359-K363 PolarHBondContact O-N 2.79Å; L360-K363 PolarHBondContact O-N 3.21Å; F361-K363 PolarHBondContact O-N 2.83Å; K363-P613 PolarHBondContact NZ-O 2.91Å; K363-F614 VanDerWaalsContact NZ-C 3.33Å; K363-F614 PolarHBondContact NZ-O 3.29Å; K363-F615 WeakPolarHBondContact CD-O 3.49Å; K363-T616 WeakPolarHBondContact CE-O 3.4Å; K363-T616 PolarHBondContact NZ-O 3.14Å; K363-R617 HydrophobicContact CG-CB 4.25Å
364	H	83.3	Confident	86.1	Confident	142 Å²	142	57.6 Å²	57.6	66%	0.657	29%	0.29	S	S	*	.	H	α-helix	trans	-91.9	-35.7	-177	-68.8	88.5	0	0	0	113.4	L360 F361	L360-H364 PolarHBondContact O-N 2.87Å; L360-H364 VanDerWaalsContact O-N 3.11Å; L360-H364 PolarHBondContact O-ND1 2.92Å; F361-H364 PolarHBondContact O-N 3.29Å; F361-H364 VanDerWaalsContact O-N 3.15Å
365	F	83.5	Confident	85.9	Confident	115 Å²	115	59.2 Å²	59.2	50%	0.504	30%	0.297	S	S	.	.	S	Bend	trans	-93.7	102.2	174.9	-65.4	-78.4	0	0	0	109.6	F361 L367	F361-F365 AromaticContact CD1-CD2 3.87Å; F361-F365 HydrophobicContact CD1-CD2 3.87Å; F361-F365 AromaticContact CD2-CD2 3.69Å; F361-F365 HydrophobicContact CD2-CD2 3.69Å; F361-F365 AromaticContact CD2-CE2 3.67Å; F361-F365 HydrophobicContact CD2-CE2 3.67Å; F361-F365 HydrophobicContact CE1-CB 4.24Å; F361-F365 AromaticContact CE1-CD2 3.75Å; F361-F365 HydrophobicContact CE1-CD2 3.75Å; F361-F365 HydrophobicContact CE1-CE2 4.45Å; F361-F365 HydrophobicContact CE1-CG 4.17Å; F361-F365 AromaticContact CE2-CD2 3.57Å; F361-F365 HydrophobicContact CE2-CD2 3.57Å; F361-F365 AromaticContact CE2-CE2 3.43Å; F361-F365 HydrophobicContact CE2-CE2 3.43Å; F361-F365 VanDerWaalsContact CE2-CE2 3.43Å; F361-F365 HydrophobicContact CE2-CZ 4.3Å; F361-F365 AromaticContact CG-CD2 3.84Å; F361-F365 HydrophobicContact CG-CD2 3.84Å; F361-F365 HydrophobicContact CG-CE2 4.29Å; F361-F365 AromaticContact CZ-CD2 3.6Å; F361-F365 HydrophobicContact CZ-CD2 3.6Å; F361-F365 AromaticContact CZ-CE2 3.86Å; F361-F365 HydrophobicContact CZ-CE2 3.86Å; F361-F365 HydrophobicContact CZ-CG 4.16Å; F361-F365 WeakPolarHBondContact O-CD2 3.42Å; F361-F365 PolarHBondContact O-N 3.23Å; F365-L367 VanDerWaalsContact C-N 3.28Å; F365-L367 HydrophobicContact CB-CG 4.32Å; F365-L367 PolarHBondContact O-N 3.06Å
366	D	75.3	Confident	85.8	Confident	73 Å²	73	60.6 Å²	60.6	39%	0.39	31%	0.311	S	S	.	.			trans	-76.4	74	-175.1	-155.8	-11.8	0	0	0	112.6	R368 R617	D366-R368 PolarHBondContact O-N 3.47Å; D366-R368 IonicContact OD1-CZ 3.85Å; D366-R368 IonicContact OD1-NE 3.59Å; D366-R368 PolarHBondContact OD1-NE 2.83Å; D366-R368 IonicContact OD1-NH2 2.64Å; D366-R368 IonicContact OD2-NH2 2.71Å; D366-R617 IonicContact OD1-NH1 3.52Å; D366-R617 PolarHBondContact OD1-NH1 2.9Å; D366-R617 IonicContact OD2-CZ 2.66Å; D366-R617 IonicContact OD2-NH1 3.71Å; D366-R617 PolarHBondContact OD2-NH1 3.19Å; D366-R617 IonicContact OD2-NH2 2.76Å; D366-R617 PolarHBondContact OD2-NH2 2.91Å
367	L	80.4	Confident	85.8	Confident	31 Å²	31	60.8 Å²	60.8	16%	0.162	31%	0.311	C	S	.	.	G	3₁₀ helix	trans	-80.1	0.8	-177.6	-62.8	178.4	0	0	0	113.8	F361 L362 F365 K369 T370 L373 E374 M377	F361-L367 HydrophobicContact CE1-CD1 4.49Å; L362-L367 HydrophobicContact CD2-CD1 4.07Å; F365-L367 VanDerWaalsContact C-N 3.28Å; F365-L367 HydrophobicContact CB-CG 4.32Å; F365-L367 PolarHBondContact O-N 3.06Å; L367-K369 PolarHBondContact O-N 3.09Å; L367-T370 CarbonylContact O-C 3.59Å; L367-T370 PolarHBondContact O-N 3.37Å; L367-T370 PolarHBondContact O-OG1 3.05Å; L367-L373 HydrophobicContact CD1-CD2 3.74Å; L367-L373 HydrophobicContact CD2-CD2 3.95Å; L367-L373 HydrophobicContact CG-CD2 4.41Å; L367-E374 HydrophobicContact CB-CB 4.05Å; L367-E374 HydrophobicContact CB-CG 4.31Å; L367-M377 HydrophobicContact CD1-CG 4.04Å
368	R	71.4	Confident	85.7	Confident	58 Å²	58	56.8 Å²	56.8	22%	0.219	29%	0.291	C	S	.	.	G	3₁₀ helix	trans	-61.8	-14.7	-176.1	-65	-177.2	-61.9	158.1	7.3	114.3	D366 E374 D623	D366-R368 PolarHBondContact O-N 3.47Å; D366-R368 IonicContact OD1-CZ 3.85Å; D366-R368 IonicContact OD1-NE 3.59Å; D366-R368 PolarHBondContact OD1-NE 2.83Å; D366-R368 IonicContact OD1-NH2 2.64Å; D366-R368 IonicContact OD2-NH2 2.71Å; R368-E374 VanDerWaalsContact CG-OE1 3.29Å; R368-E374 WeakPolarHBondContact CG-OE1 3.49Å; R368-D623 IonicContact CZ-OD2 2.7Å; R368-D623 VanDerWaalsContact CZ-OD2 3.23Å; R368-D623 IonicContact NH1-OD2 2.6Å; R368-D623 PolarHBondContact NH1-OD2 3.34Å; R368-D623 IonicContact NH2-OD2 3.12Å; R368-D623 PolarHBondContact NH2-OD2 3.23Å
369	K	76.9	Confident	85.7	Confident	194 Å²	194	60.2 Å²	60.2	84%	0.843	31%	0.308	S	S	*	.	G	3₁₀ helix	trans	-80.7	-12.5	172	-65.5	-175.7	179.7	-179.3	0	113.8	L367	L367-K369 PolarHBondContact O-N 3.09Å
370	T	84.6	Confident	85.9	Confident	70 Å²	70	65 Å²	65	43%	0.429	33%	0.333	S	S	.	.			trans	-135.3	73.1	-178.4	45.6	0	0	0	0	111	L367 S372 L373 E374	L367-T370 CarbonylContact O-C 3.59Å; L367-T370 PolarHBondContact O-N 3.37Å; L367-T370 PolarHBondContact O-OG1 3.05Å; T370-S372 PolarHBondContact O-N 2.92Å; T370-L373 WeakPolarHBondContact O-CB 3.43Å; T370-L373 PolarHBondContact O-N 3.08Å; T370-E374 PolarHBondContact O-N 3.34Å; T370-E374 VanDerWaalsContact O-N 3.17Å
371	P	82.9	Confident	86.1	Confident	37 Å²	37	63.4 Å²	63.4	24%	0.24	32%	0.324	C	S	.	.	H	α-helix	trans	-50.4	-37	-174.3	-30.9	37.3	0	0	0	115.1	L373 E374 F375 I418	P371-L373 VanDerWaalsContact C-N 3.29Å; P371-L373 PolarHBondContact O-N 3.43Å; P371-E374 WeakPolarHBondContact O-CB 3.09Å; P371-E374 PolarHBondContact O-N 3Å; P371-F375 VanDerWaalsContact O-CB 3.28Å; P371-F375 WeakPolarHBondContact O-CB 3.47Å; P371-F375 PolarHBondContact O-N 2.71Å; P371-I418 HydrophobicContact CB-CG2 4.42Å
372	S	87.3	Confident	86.2	Confident	105 Å²	105	61 Å²	61	73%	0.734	32%	0.316	S	S	*	.	H	α-helix	trans	-63.4	-32.4	178.4	-39.7	0	0	0	0	113.6	T370 G376	T370-S372 PolarHBondContact O-N 2.92Å; S372-G376 PolarHBondContact O-N 2.97Å
373	L	88.1	Confident	86.4	Confident	92 Å²	92	65.5 Å²	65.5	48%	0.482	33%	0.333	S	S	.	.	H	α-helix	trans	-80.7	-41.8	177.9	-158.8	166	0	0	0	110	L367 T370 P371 F375 G376 M377	L367-L373 HydrophobicContact CD1-CD2 3.74Å; L367-L373 HydrophobicContact CD2-CD2 3.95Å; L367-L373 HydrophobicContact CG-CD2 4.41Å; T370-L373 WeakPolarHBondContact O-CB 3.43Å; T370-L373 PolarHBondContact O-N 3.08Å; P371-L373 VanDerWaalsContact C-N 3.29Å; P371-L373 PolarHBondContact O-N 3.43Å; L373-F375 VanDerWaalsContact C-N 3.35Å; L373-F375 PolarHBondContact O-N 3.46Å; L373-G376 PolarHBondContact O-N 3.49Å; L373-M377 HydrophobicContact CD2-CG 4.02Å; L373-M377 WeakPolarHBondContact O-CG 3.02Å; L373-M377 PolarHBondContact O-N 3.17Å
374	E	90.4	Very high	86.8	Confident	3 Å²	3	66.4 Å²	66.4	1%	0.014	34%	0.34	C	S	.	.	H	α-helix	trans	-55.1	-47.8	171.7	-168.5	-177.3	-141.9	0	0	111.7	L362 L367 R368 T370 P371 M377 M378 L415 S416 T419	L362-E374 HydrophobicContact CD2-CG 4.12Å; L367-E374 HydrophobicContact CB-CB 4.05Å; L367-E374 HydrophobicContact CB-CG 4.31Å; R368-E374 VanDerWaalsContact CG-OE1 3.29Å; R368-E374 WeakPolarHBondContact CG-OE1 3.49Å; T370-E374 PolarHBondContact O-N 3.34Å; T370-E374 VanDerWaalsContact O-N 3.17Å; P371-E374 WeakPolarHBondContact O-CB 3.09Å; P371-E374 PolarHBondContact O-N 3Å; E374-M377 PolarHBondContact O-N 3.37Å; E374-M378 PolarHBondContact O-N 3.28Å; E374-M378 VanDerWaalsContact O-N 3.08Å; E374-L415 HydrophobicContact CG-CD2 3.72Å; E374-L415 VanDerWaalsContact OE1-CA 3.31Å; E374-L415 WeakPolarHBondContact OE1-CA 3.4Å; E374-S416 PolarHBondContact OE1-N 3.31Å; E374-S416 WeakPolarHBondContact OE2-CB 2.98Å; E374-S416 PolarHBondContact OE2-N 2.9Å; E374-S416 PolarHBondContact OE2-OG 2.89Å; E374-T419 HydrophobicContact CB-CG2 4.36Å; E374-T419 HydrophobicContact CG-CG2 4.04Å; E374-T419 WeakPolarHBondContact OE2-CB 3.5Å; E374-T419 PolarHBondContact OE2-OG1 3.1Å
375	F	90.4	Very high	87.4	Confident	41 Å²	41	59.6 Å²	59.6	18%	0.18	31%	0.308	C	S	.	.	H	α-helix	trans	-63.1	-45.2	173.5	177.4	-100.9	0	0	0	112.6	P371 L373 M377 M378 I379 T419 L422 M423 T426	P371-F375 VanDerWaalsContact O-CB 3.28Å; P371-F375 WeakPolarHBondContact O-CB 3.47Å; P371-F375 PolarHBondContact O-N 2.71Å; L373-F375 VanDerWaalsContact C-N 3.35Å; L373-F375 PolarHBondContact O-N 3.46Å; F375-M377 VanDerWaalsContact C-N 3.31Å; F375-M377 PolarHBondContact O-N 3.03Å; F375-M378 WeakPolarHBondContact O-CB 3.41Å; F375-M378 PolarHBondContact O-N 3.06Å; F375-M378 VanDerWaalsContact O-N 3.09Å; F375-I379 HydrophobicContact CD1-CG1 4.42Å; F375-I379 HydrophobicContact CE1-CD1 4.46Å; F375-I379 HydrophobicContact CE1-CG1 3.88Å; F375-I379 HydrophobicContact CE2-CD1 4.1Å; F375-I379 HydrophobicContact CE2-CG1 4.15Å; F375-I379 HydrophobicContact CZ-CD1 3.81Å; F375-I379 HydrophobicContact CZ-CG1 3.72Å; F375-I379 PolarHBondContact O-N 3.17Å; F375-T419 HydrophobicContact CB-CG2 4.05Å; F375-L422 HydrophobicContact CB-CD2 4.12Å; F375-L422 HydrophobicContact CD1-CD2 4.36Å; F375-L422 HydrophobicContact CD2-CD2 3.85Å; F375-L422 HydrophobicContact CD2-CG 3.9Å; F375-L422 HydrophobicContact CE2-CD2 4.41Å; F375-L422 HydrophobicContact CE2-CG 4.08Å; F375-L422 HydrophobicContact CG-CD2 3.83Å; F375-L422 HydrophobicContact CG-CG 4.37Å; F375-M423 HydrophobicContact CD2-SD 3.89Å; F375-M423 HydrophobicContact CE2-SD 3.73Å; F375-T426 HydrophobicContact CE2-CG2 4.45Å; F375-T426 HydrophobicContact CZ-CG2 3.85Å
376	G	91.2	Very high	87.8	Confident	29 Å²	29	55.1 Å²	55.1	30%	0.299	29%	0.288	S	S	.	.	H	α-helix	trans	-57.4	-42.6	176.2	0	0	0	0	0	112.8	S372 L373 I379 I380	S372-G376 PolarHBondContact O-N 2.97Å; L373-G376 PolarHBondContact O-N 3.49Å; G376-I379 PolarHBondContact O-N 2.99Å; G376-I380 WeakPolarHBondContact O-CG1 3.21Å; G376-I380 PolarHBondContact O-N 3.45Å; G376-I380 VanDerWaalsContact O-N 3.11Å
377	M	90.9	Very high	88.5	Confident	38 Å²	38	53.7 Å²	53.7	19%	0.187	29%	0.291	C	S	.	.	H	α-helix	trans	-64.7	-38.2	174.2	-72.2	-56.7	-51.2	0	0	112.6	F361 L367 L373 E374 F375 I380 F381	F361-M377 HydrophobicContact CD1-CE 4.37Å; F361-M377 HydrophobicContact CE1-CE 3.8Å; F361-M377 HydrophobicContact CZ-CE 4.02Å; L367-M377 HydrophobicContact CD1-CG 4.04Å; L373-M377 HydrophobicContact CD2-CG 4.02Å; L373-M377 WeakPolarHBondContact O-CG 3.02Å; L373-M377 PolarHBondContact O-N 3.17Å; E374-M377 PolarHBondContact O-N 3.37Å; F375-M377 VanDerWaalsContact C-N 3.31Å; F375-M377 PolarHBondContact O-N 3.03Å; M377-I380 PolarHBondContact O-N 3.22Å; M377-I380 HydrophobicContact SD-CD1 4.22Å; M377-F381 HydrophobicContact CE-CD2 4.14Å; M377-F381 HydrophobicContact CE-CE2 3.55Å; M377-F381 HydrophobicContact CE-CZ 4.15Å; M377-F381 WeakPolarHBondContact O-CD2 3.18Å; M377-F381 PolarHBondContact O-N 3.3Å
378	M	91.2	Very high	89.1	Confident	0 Å²	0	55.9 Å²	55.9	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-61.5	-41.6	175.3	-80.2	-66.7	-64.2	0	0	112.6	Y215 L362 E374 F375 F381 A382 M407 T411 L415 M423	Y215-M378 HydrophobicContact CE2-CE 3.97Å; L362-M378 HydrophobicContact CD1-CG 4.13Å; L362-M378 HydrophobicContact CD1-SD 3.6Å; L362-M378 VanDerWaalsContact CD1-SD 3.6Å; E374-M378 PolarHBondContact O-N 3.28Å; E374-M378 VanDerWaalsContact O-N 3.08Å; F375-M378 WeakPolarHBondContact O-CB 3.41Å; F375-M378 PolarHBondContact O-N 3.06Å; F375-M378 VanDerWaalsContact O-N 3.09Å; M378-F381 PolarHBondContact O-N 3.33Å; M378-A382 WeakPolarHBondContact O-CB 3.42Å; M378-A382 PolarHBondContact O-N 2.89Å; M378-M407 HydrophobicContact CE-CE 3.57Å; M378-M407 HydrophobicContact SD-CE 3.81Å; M378-T411 HydrophobicContact CE-CG2 4.31Å; M378-T411 HydrophobicContact SD-CG2 3.49Å; M378-T411 WeakPolarHBondContact SD-CG2 3.38Å; M378-L415 HydrophobicContact CE-CD1 4.02Å; M378-L415 HydrophobicContact CG-CD1 4.15Å; M378-L415 HydrophobicContact CG-CD2 3.62Å; M378-L415 HydrophobicContact SD-CD1 4.11Å; M378-L415 HydrophobicContact SD-CD2 3.9Å; M378-L415 HydrophobicContact SD-CG 4.44Å; M378-M423 HydrophobicContact CB-CE 3.77Å; M378-M423 HydrophobicContact CB-SD 3.65Å; M378-M423 HydrophobicContact CE-CE 3.89Å; M378-M423 HydrophobicContact CE-CG 4.18Å; M378-M423 HydrophobicContact CE-SD 4.29Å; M378-M423 HydrophobicContact CG-SD 4.42Å
379	I	92	Very high	90.2	Very high	71 Å²	71	53.1 Å²	53.1	36%	0.364	29%	0.292	S	S	.	.	H	α-helix	trans	-66.7	-39.3	176.1	-61.8	-63.6	0	0	0	111.4	F375 G376 A382 Y383 M423	F375-I379 HydrophobicContact CD1-CG1 4.42Å; F375-I379 HydrophobicContact CE1-CD1 4.46Å; F375-I379 HydrophobicContact CE1-CG1 3.88Å; F375-I379 HydrophobicContact CE2-CD1 4.1Å; F375-I379 HydrophobicContact CE2-CG1 4.15Å; F375-I379 HydrophobicContact CZ-CD1 3.81Å; F375-I379 HydrophobicContact CZ-CG1 3.72Å; F375-I379 PolarHBondContact O-N 3.17Å; G376-I379 PolarHBondContact O-N 2.99Å; I379-A382 PolarHBondContact O-N 3.49Å; I379-Y383 PolarHBondContact O-N 3.22Å; I379-M423 HydrophobicContact CD1-CE 3.89Å; I379-M423 HydrophobicContact CD1-SD 4.12Å
380	I	93	Very high	90.7	Very high	102 Å²	102	48.3 Å²	48.3	52%	0.523	27%	0.272	S	S	.	.	H	α-helix	trans	-61.6	-47.5	173.9	-67.8	165.2	0	0	0	110.7	G376 M377 A382 Y383 L384	G376-I380 WeakPolarHBondContact O-CG1 3.21Å; G376-I380 PolarHBondContact O-N 3.45Å; G376-I380 VanDerWaalsContact O-N 3.11Å; M377-I380 PolarHBondContact O-N 3.22Å; M377-I380 HydrophobicContact SD-CD1 4.22Å; I380-A382 VanDerWaalsContact C-N 3.28Å; I380-A382 PolarHBondContact O-N 2.92Å; I380-Y383 PolarHBondContact O-N 2.9Å; I380-L384 VanDerWaalsContact O-CB 3.32Å; I380-L384 WeakPolarHBondContact O-CB 3.28Å; I380-L384 PolarHBondContact O-N 3.48Å
381	F	93.1	Very high	90.8	Very high	13 Å²	13	48.1 Å²	48.1	6%	0.057	29%	0.285	C	S	.	.	H	α-helix	trans	-67.3	-25	178.2	-80.3	-61.9	0	0	0	113.8	I357 S358 F361 M377 M378 L384 P385 M407	I357-F381 HydrophobicContact CG2-CE1 4.29Å; S358-F381 WeakPolarHBondContact OG-CB 3.41Å; S358-F381 WeakPolarHBondContact OG-CD2 3.25Å; S358-F381 VanDerWaalsContact OG-CG 3.29Å; S358-F381 WeakPolarHBondContact OG-CG 3.35Å; F361-F381 HydrophobicContact CB-CE2 4.03Å; F361-F381 HydrophobicContact CB-CZ 3.83Å; F361-F381 AromaticContact CD1-CE2 3.81Å; F361-F381 HydrophobicContact CD1-CE2 3.81Å; F361-F381 HydrophobicContact CD1-CZ 4.17Å; F361-F381 HydrophobicContact CD2-CZ 4.14Å; F361-F381 HydrophobicContact CE1-CE2 4.45Å; F361-F381 AromaticContact CG-CE2 3.89Å; F361-F381 HydrophobicContact CG-CE2 3.89Å; F361-F381 AromaticContact CG-CZ 3.78Å; F361-F381 HydrophobicContact CG-CZ 3.78Å; M377-F381 HydrophobicContact CE-CD2 4.14Å; M377-F381 HydrophobicContact CE-CE2 3.55Å; M377-F381 HydrophobicContact CE-CZ 4.15Å; M377-F381 WeakPolarHBondContact O-CD2 3.18Å; M377-F381 PolarHBondContact O-N 3.3Å; M378-F381 PolarHBondContact O-N 3.33Å; F381-L384 HydrophobicContact CD1-CD2 3.91Å; F381-L384 HydrophobicContact CE1-CD2 4.09Å; F381-P385 WeakPolarHBondContact O-CD 3.24Å; F381-M407 HydrophobicContact CB-CE 3.69Å; F381-M407 HydrophobicContact CB-SD 4.21Å
382	A	92.3	Very high	91.1	Very high	12 Å²	12	50.3 Å²	50.3	10%	0.099	30%	0.297	C	S	.	.	H	α-helix	trans	-68.7	-36.9	174.5	0	0	0	0	0	112.9	F211 M378 I379 I380 P385	F211-A382 HydrophobicContact CD1-CB 3.82Å; F211-A382 HydrophobicContact CD2-CB 3.81Å; F211-A382 HydrophobicContact CE1-CB 3.6Å; F211-A382 HydrophobicContact CE2-CB 3.59Å; F211-A382 HydrophobicContact CG-CB 3.92Å; F211-A382 HydrophobicContact CZ-CB 3.48Å; F211-A382 VanDerWaalsContact CZ-CB 3.48Å; M378-A382 WeakPolarHBondContact O-CB 3.42Å; M378-A382 PolarHBondContact O-N 2.89Å; I379-A382 PolarHBondContact O-N 3.49Å; I380-A382 VanDerWaalsContact C-N 3.28Å; I380-A382 PolarHBondContact O-N 2.92Å; A382-P385 VanDerWaalsContact O-CG 3.28Å; A382-P385 WeakPolarHBondContact O-CG 3.36Å
383	Y	91.8	Very high	91.1	Very high	102 Å²	102	53.2 Å²	53.2	40%	0.4	30%	0.299	S	S	.	.	H	α-helix	trans	-95.9	-25.8	-177.7	-160.5	-88.3	0	0	0	113.8	L203 P207 I379 I380 P385 Y386	L203-Y383 PolarHBondContact O-OH 2.86Å; P207-Y383 HydrophobicContact CB-CD2 4.11Å; P207-Y383 HydrophobicContact CB-CE2 3.81Å; P207-Y383 HydrophobicContact CG-CE2 4.02Å; I379-Y383 PolarHBondContact O-N 3.22Å; I380-Y383 PolarHBondContact O-N 2.9Å; Y383-P385 VanDerWaalsContact C-CD 3.45Å; Y383-Y386 AromaticContact CE1-CD1 3.85Å; Y383-Y386 HydrophobicContact CE1-CD1 3.85Å; Y383-Y386 HydrophobicContact CE2-CD1 4.42Å; Y383-Y386 AromaticContact CZ-CD1 3.68Å; Y383-Y386 VanDerWaalsContact O-CB 3.26Å; Y383-Y386 WeakPolarHBondContact O-CB 3.34Å; Y383-Y386 PolarHBondContact O-N 2.88Å; Y383-Y386 WeakPolarHBondContact OH-CD1 3.33Å
384	L	93.6	Very high	91.2	Very high	66 Å²	66	50.1 Å²	50.1	35%	0.346	28%	0.283	S	S	.	.	H	α-helix	trans	-45.4	-46.4	172.8	-176.1	64.5	0	0	0	115.6	I380 F381 Y386 G387 L388	I380-L384 VanDerWaalsContact O-CB 3.32Å; I380-L384 WeakPolarHBondContact O-CB 3.28Å; I380-L384 PolarHBondContact O-N 3.48Å; F381-L384 HydrophobicContact CD1-CD2 3.91Å; F381-L384 HydrophobicContact CE1-CD2 4.09Å; L384-Y386 PolarHBondContact O-N 3.37Å; L384-G387 PolarHBondContact O-N 2.91Å; L384-L388 HydrophobicContact CD1-CD1 3.89Å; L384-L388 HydrophobicContact CD1-CG 3.99Å; L384-L388 HydrophobicContact CD2-CD1 4.38Å; L384-L388 HydrophobicContact CG-CD1 3.8Å; L384-L388 HydrophobicContact CG-CG 4.29Å; L384-L388 WeakPolarHBondContact O-CG 3.13Å; L384-L388 PolarHBondContact O-N 3.07Å; L384-L388 VanDerWaalsContact O-N 3.15Å
385	P	94.8	Very high	91.2	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-55.7	-31.5	176.8	18.8	-34.5	0	0	0	114.4	F381 A382 Y383 A389 S399 I400 A403	F381-P385 WeakPolarHBondContact O-CD 3.24Å; A382-P385 VanDerWaalsContact O-CG 3.28Å; A382-P385 WeakPolarHBondContact O-CG 3.36Å; Y383-P385 VanDerWaalsContact C-CD 3.45Å; P385-A389 PolarHBondContact O-N 3.02Å; P385-S399 WeakPolarHBondContact CB-OG 3.47Å; P385-S399 VanDerWaalsContact O-CB 3.31Å; P385-S399 WeakPolarHBondContact O-CB 3.2Å; P385-S399 PolarHBondContact O-OG 3.33Å; P385-I400 HydrophobicContact CG-CG1 4.37Å; P385-A403 HydrophobicContact CB-CB 3.8Å; P385-A403 HydrophobicContact CG-CB 3.62Å
386	Y	92	Very high	91.1	Very high	20 Å²	20	48.2 Å²	48.2	8%	0.078	28%	0.275	C	S	.	.	H	α-helix	trans	-66.8	-59.4	178.4	-175.7	-103.5	0	0	0	110.8	F202 L203 P207 Y383 L384 L388 A389 E390 I397 I400	F202-Y386 PolarHBondContact O-OH 2.79Å; L203-Y386 WeakPolarHBondContact CD1-OH 3.41Å; L203-Y386 HydrophobicContact CG-CE1 4.2Å; P207-Y386 HydrophobicContact CG-CD2 4.49Å; P207-Y386 HydrophobicContact CG-CE2 4.44Å; Y383-Y386 AromaticContact CE1-CD1 3.85Å; Y383-Y386 HydrophobicContact CE1-CD1 3.85Å; Y383-Y386 HydrophobicContact CE2-CD1 4.42Å; Y383-Y386 AromaticContact CZ-CD1 3.68Å; Y383-Y386 VanDerWaalsContact O-CB 3.26Å; Y383-Y386 WeakPolarHBondContact O-CB 3.34Å; Y383-Y386 PolarHBondContact O-N 2.88Å; Y383-Y386 WeakPolarHBondContact OH-CD1 3.33Å; L384-Y386 PolarHBondContact O-N 3.37Å; Y386-L388 VanDerWaalsContact C-N 3.25Å; Y386-L388 PolarHBondContact O-N 3.19Å; Y386-A389 PolarHBondContact O-N 2.78Å; Y386-E390 HydrophobicContact CD1-CG 4.36Å; Y386-E390 HydrophobicContact CD2-CG 4.46Å; Y386-E390 HydrophobicContact CE1-CG 4.07Å; Y386-E390 HydrophobicContact CE2-CG 4.19Å; Y386-E390 WeakPolarHBondContact O-CG 3.36Å; Y386-E390 PolarHBondContact O-N 3.43Å; Y386-I397 HydrophobicContact CE2-CG1 4.21Å; Y386-I400 HydrophobicContact CD2-CD1 3.46Å; Y386-I400 VanDerWaalsContact CD2-CD1 3.46Å; Y386-I400 HydrophobicContact CD2-CG1 4.27Å; Y386-I400 HydrophobicContact CE2-CD1 4.41Å; Y386-I400 HydrophobicContact CG-CD1 3.95Å; Y386-I400 HydrophobicContact CG-CG1 4.49Å
387	G	91	Very high	91.1	Very high	43 Å²	43	47.2 Å²	47.2	44%	0.443	26%	0.263	S	S	.	.	H	α-helix	trans	-61.3	-32.7	-176.7	0	0	0	0	0	113.4	L384 G391	L384-G387 PolarHBondContact O-N 2.91Å; G387-G391 PolarHBondContact O-N 2.8Å
388	L	93.1	Very high	91	Very high	77 Å²	77	45.4 Å²	45.4	40%	0.403	25%	0.254	S	S	.	.	H	α-helix	trans	-71.7	-35.4	174.7	-68.8	178	0	0	0	113.1	L350 T354 L384 Y386 T392	L350-L388 HydrophobicContact CD2-CB 4.12Å; T354-L388 HydrophobicContact CG2-CD1 3.78Å; L384-L388 HydrophobicContact CD1-CD1 3.89Å; L384-L388 HydrophobicContact CD1-CG 3.99Å; L384-L388 HydrophobicContact CD2-CD1 4.38Å; L384-L388 HydrophobicContact CG-CD1 3.8Å; L384-L388 HydrophobicContact CG-CG 4.29Å; L384-L388 WeakPolarHBondContact O-CG 3.13Å; L384-L388 PolarHBondContact O-N 3.07Å; L384-L388 VanDerWaalsContact O-N 3.15Å; Y386-L388 VanDerWaalsContact C-N 3.25Å; Y386-L388 PolarHBondContact O-N 3.19Å; L388-T392 WeakPolarHBondContact O-CB 3.33Å; L388-T392 WeakPolarHBondContact O-CG2 3.34Å; L388-T392 PolarHBondContact O-N 3.07Å; L388-T392 PolarHBondContact O-OG1 3.08Å
389	A	92.6	Very high	91.1	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-74.9	-47.3	178	0	0	0	0	0	111.3	L350 P385 Y386 G391 T392 Q393 L394	L350-A389 VanDerWaalsContact CD2-CA 3.49Å; L350-A389 HydrophobicContact CD2-CB 3.66Å; P385-A389 PolarHBondContact O-N 3.02Å; Y386-A389 PolarHBondContact O-N 2.78Å; A389-G391 VanDerWaalsContact C-N 3.28Å; A389-G391 PolarHBondContact O-N 2.94Å; A389-T392 WeakPolarHBondContact CA-OG1 3.15Å; A389-T392 CarbonylContact O-C 3.38Å; A389-T392 WeakPolarHBondContact O-CA 3.34Å; A389-T392 PolarHBondContact O-N 2.82Å; A389-T392 PolarHBondContact O-OG1 3.22Å; A389-T392 VanDerWaalsContact O-OG1 3.07Å; A389-Q393 PolarHBondContact O-N 2.95Å; A389-L394 CarbonylContact C-O 3.59Å; A389-L394 VanDerWaalsContact C-O 3.23Å; A389-L394 HydrophobicContact CB-CB 3.91Å; A389-L394 PolarHBondContact O-N 2.92Å; A389-L394 VanDerWaalsContact O-O 3.1Å
390	E	87.8	Confident	91.2	Very high	93 Å²	93	42.1 Å²	42.1	44%	0.435	24%	0.237	S	C	.	.	H	α-helix	trans	-58.8	-42.7	176.4	-62.9	-57.3	140.7	0	0	110.7	Y386 T392 Q393 G396	Y386-E390 HydrophobicContact CD1-CG 4.36Å; Y386-E390 HydrophobicContact CD2-CG 4.46Å; Y386-E390 HydrophobicContact CE1-CG 4.07Å; Y386-E390 HydrophobicContact CE2-CG 4.19Å; Y386-E390 WeakPolarHBondContact O-CG 3.36Å; Y386-E390 PolarHBondContact O-N 3.43Å; E390-T392 PolarHBondContact O-N 2.93Å; E390-Q393 PolarHBondContact O-N 2.93Å; E390-G396 VanDerWaalsContact OE1-CA 3.32Å; E390-G396 WeakPolarHBondContact OE1-CA 3.44Å; E390-G396 PolarHBondContact OE1-N 3.43Å
391	G	87.9	Confident	91.2	Very high	67 Å²	67	37.2 Å²	37.2	69%	0.691	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	-64.8	-14.5	173.1	0	0	0	0	0	115.5	G387 A389	G387-G391 PolarHBondContact O-N 2.8Å; A389-G391 VanDerWaalsContact C-N 3.28Å; A389-G391 PolarHBondContact O-N 2.94Å
392	T	89.3	Confident	91.1	Very high	82 Å²	82	38.9 Å²	38.9	50%	0.503	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-111.7	10.6	176.1	52.2	0	0	0	0	113.5	L388 A389 E390 L394	L388-T392 WeakPolarHBondContact O-CB 3.33Å; L388-T392 WeakPolarHBondContact O-CG2 3.34Å; L388-T392 PolarHBondContact O-N 3.07Å; L388-T392 PolarHBondContact O-OG1 3.08Å; A389-T392 WeakPolarHBondContact CA-OG1 3.15Å; A389-T392 CarbonylContact O-C 3.38Å; A389-T392 WeakPolarHBondContact O-CA 3.34Å; A389-T392 PolarHBondContact O-N 2.82Å; A389-T392 PolarHBondContact O-OG1 3.22Å; A389-T392 VanDerWaalsContact O-OG1 3.07Å; E390-T392 PolarHBondContact O-N 2.93Å; T392-L394 PolarHBondContact O-N 3.43Å
393	Q	86.9	Confident	91.1	Very high	167 Å²	167	38.3 Å²	38.3	78%	0.78	21%	0.214	S	C	*	.	T	Hydrogen-bonded Turn	trans	57.9	35	-175.9	-55.3	-179.1	-5.3	0	0	113.3	M343 A389 E390	M343-Q393 WeakPolarHBondContact CE-O 3.28Å; A389-Q393 PolarHBondContact O-N 2.95Å; E390-Q393 PolarHBondContact O-N 2.93Å
394	L	89.9	Confident	91.2	Very high	27 Å²	27	33.4 Å²	33.4	14%	0.141	20%	0.195	C	C	.	.	S	Bend	trans	-109.2	161.7	170	-67.1	174.7	0	0	0	109.2	M343 L350 A389 T392 G396	M343-L394 HydrophobicContact SD-CD2 4.1Å; L350-L394 HydrophobicContact CD2-CD1 4.34Å; A389-L394 CarbonylContact C-O 3.59Å; A389-L394 VanDerWaalsContact C-O 3.23Å; A389-L394 HydrophobicContact CB-CB 3.91Å; A389-L394 PolarHBondContact O-N 2.92Å; A389-L394 VanDerWaalsContact O-O 3.1Å; T392-L394 PolarHBondContact O-N 3.43Å; L394-G396 PolarHBondContact O-N 3.39Å
395	S	89.6	Confident	90.9	Very high	4 Å²	4	31 Å²	31	3%	0.028	18%	0.183	C	C	.	.			trans	-69.8	114.9	176.8	175.7	0	0	0	0	111	S347 I397 M398 S399	S347-S395 WeakPolarHBondContact CB-O 3.48Å; S347-S395 WeakPolarHBondContact OG-CA 3.45Å; S347-S395 WeakPolarHBondContact OG-CB 3.35Å; S347-S395 PolarHBondContact OG-N 3.07Å; S347-S395 PolarHBondContact OG-O 3.49Å; S395-I397 PolarHBondContact O-N 3.13Å; S395-M398 PolarHBondContact OG-N 3.13Å; S395-S399 WeakPolarHBondContact O-CB 3.35Å; S395-S399 PolarHBondContact O-N 3.39Å
396	G	90.1	Very high	90.6	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-62.2	-34	174.6	0	0	0	0	0	112.4	E390 L394 S399 I400	E390-G396 VanDerWaalsContact OE1-CA 3.32Å; E390-G396 WeakPolarHBondContact OE1-CA 3.44Å; E390-G396 PolarHBondContact OE1-N 3.43Å; L394-G396 PolarHBondContact O-N 3.39Å; G396-S399 WeakPolarHBondContact O-CB 3.29Å; G396-S399 PolarHBondContact O-N 3.43Å; G396-I400 VanDerWaalsContact O-CG1 3.29Å; G396-I400 WeakPolarHBondContact O-CG1 3.29Å; G396-I400 PolarHBondContact O-N 3.4Å
397	I	89.6	Confident	90.6	Very high	7 Å²	7	30.9 Å²	30.9	4%	0.036	18%	0.184	C	C	.	.	H	α-helix	trans	-68.4	-46.7	-176.5	-61.3	171.2	0	0	0	111.2	F202 L206 I210 I309 Y386 S395 S399 I400 L401	F202-I397 HydrophobicContact CD1-CD1 3.75Å; F202-I397 HydrophobicContact CE1-CD1 4.05Å; L206-I397 HydrophobicContact CD1-CD1 4.17Å; L206-I397 HydrophobicContact CD2-CB 4.23Å; L206-I397 HydrophobicContact CD2-CD1 3.68Å; L206-I397 HydrophobicContact CD2-CG1 3.59Å; L206-I397 HydrophobicContact CD2-CG2 3.73Å; I210-I397 HydrophobicContact CG1-CG2 4.28Å; I210-I397 HydrophobicContact CG2-CG2 4.42Å; I309-I397 HydrophobicContact CD1-CD1 3.88Å; I309-I397 HydrophobicContact CD1-CG2 3.96Å; I309-I397 HydrophobicContact CG2-CD1 4.16Å; Y386-I397 HydrophobicContact CE2-CG1 4.21Å; S395-I397 PolarHBondContact O-N 3.13Å; I397-S399 VanDerWaalsContact C-N 3.27Å; I397-S399 PolarHBondContact O-N 2.91Å; I397-I400 PolarHBondContact O-N 2.83Å; I397-L401 PolarHBondContact O-N 2.69Å; I397-L401 VanDerWaalsContact O-N 3.11Å
398	M	89.8	Confident	90.3	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.005	17%	0.165	C	C	.	.	H	α-helix	trans	-67.9	-29.6	174.7	-173.5	57.1	122.2	0	0	112	A306 V307 V310 F344 S395 L401 F402	A306-M398 HydrophobicContact CB-CB 4.35Å; A306-M398 HydrophobicContact CB-CE 4.13Å; A306-M398 HydrophobicContact CB-SD 3.59Å; A306-M398 VanDerWaalsContact CB-SD 3.59Å; V307-M398 HydrophobicContact CG2-CE 3.91Å; V310-M398 HydrophobicContact CG2-CB 4.25Å; F344-M398 HydrophobicContact CD2-CE 3.49Å; F344-M398 VanDerWaalsContact CD2-CE 3.49Å; F344-M398 HydrophobicContact CE2-CE 3.32Å; F344-M398 HydrophobicContact CG-CE 4.49Å; F344-M398 HydrophobicContact CZ-CE 4.22Å; S395-M398 PolarHBondContact OG-N 3.13Å; M398-L401 HydrophobicContact SD-CD2 4.33Å; M398-F402 HydrophobicContact CE-CE2 3.98Å; M398-F402 HydrophobicContact CG-CD2 4.2Å; M398-F402 HydrophobicContact CG-CE2 4.35Å; M398-F402 PolarHBondContact O-N 2.78Å; M398-F402 HydrophobicContact SD-CD2 3.69Å; M398-F402 HydrophobicContact SD-CE2 3.56Å; M398-F402 VanDerWaalsContact SD-CE2 3.56Å
399	S	94.1	Very high	89.9	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-66.7	-46.8	173.3	-170.6	0	0	0	0	111.8	G351 P385 S395 G396 I397 L401 A403	G351-S399 WeakPolarHBondContact CA-O 3.4Å; G351-S399 PolarHBondContact N-OG 3.33Å; P385-S399 WeakPolarHBondContact CB-OG 3.47Å; P385-S399 VanDerWaalsContact O-CB 3.31Å; P385-S399 WeakPolarHBondContact O-CB 3.2Å; P385-S399 PolarHBondContact O-OG 3.33Å; S395-S399 WeakPolarHBondContact O-CB 3.35Å; S395-S399 PolarHBondContact O-N 3.39Å; G396-S399 WeakPolarHBondContact O-CB 3.29Å; G396-S399 PolarHBondContact O-N 3.43Å; I397-S399 VanDerWaalsContact C-N 3.27Å; I397-S399 PolarHBondContact O-N 2.91Å; S399-L401 VanDerWaalsContact C-N 3.32Å; S399-L401 PolarHBondContact O-N 2.78Å; S399-A403 VanDerWaalsContact O-CB 3.3Å; S399-A403 WeakPolarHBondContact O-CB 3.41Å; S399-A403 PolarHBondContact O-N 2.79Å
400	I	94	Very high	89.5	Confident	1 Å²	1	27.1 Å²	27.1	1%	0.005	15%	0.153	C	C	.	.	H	α-helix	trans	-55.1	-48.1	173.3	-66.6	158.1	0	0	0	110.5	P207 I210 F211 P385 Y386 G396 I397 A403 G404	P207-I400 HydrophobicContact CB-CD1 3.61Å; P207-I400 HydrophobicContact CG-CD1 4.03Å; I210-I400 HydrophobicContact CG2-CG2 4.27Å; F211-I400 HydrophobicContact CB-CG2 3.65Å; F211-I400 HydrophobicContact CD2-CG2 3.88Å; F211-I400 HydrophobicContact CG-CG2 4.27Å; P385-I400 HydrophobicContact CG-CG1 4.37Å; Y386-I400 HydrophobicContact CD2-CD1 3.46Å; Y386-I400 VanDerWaalsContact CD2-CD1 3.46Å; Y386-I400 HydrophobicContact CD2-CG1 4.27Å; Y386-I400 HydrophobicContact CE2-CD1 4.41Å; Y386-I400 HydrophobicContact CG-CD1 3.95Å; Y386-I400 HydrophobicContact CG-CG1 4.49Å; G396-I400 VanDerWaalsContact O-CG1 3.29Å; G396-I400 WeakPolarHBondContact O-CG1 3.29Å; G396-I400 PolarHBondContact O-N 3.4Å; I397-I400 PolarHBondContact O-N 2.83Å; I400-A403 WeakPolarHBondContact O-CB 3.34Å; I400-A403 PolarHBondContact O-N 2.98Å; I400-G404 PolarHBondContact O-N 2.85Å
401	L	91.1	Very high	89.5	Confident	0 Å²	0	22.7 Å²	22.7	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-61.1	-50.9	-173.8	-179.6	50.8	0	0	0	112	I210 I302 L303 A306 I397 M398 S399 A403 G404 I405	I210-L401 HydrophobicContact CG2-CB 3.72Å; I210-L401 HydrophobicContact CG2-CD1 4.22Å; I210-L401 HydrophobicContact CG2-CG 4.39Å; I302-L401 HydrophobicContact CG2-CD1 3.45Å; I302-L401 VanDerWaalsContact CG2-CD1 3.45Å; I302-L401 HydrophobicContact CG2-CD2 4.03Å; I302-L401 HydrophobicContact CG2-CG 4.36Å; I302-L401 WeakPolarHBondContact O-CD2 3.5Å; L303-L401 HydrophobicContact CD2-CD2 3.89Å; L303-L401 HydrophobicContact CD2-CG 4.45Å; A306-L401 HydrophobicContact CB-CD2 3.68Å; I397-L401 PolarHBondContact O-N 2.69Å; I397-L401 VanDerWaalsContact O-N 3.11Å; M398-L401 HydrophobicContact SD-CD2 4.33Å; S399-L401 VanDerWaalsContact C-N 3.32Å; S399-L401 PolarHBondContact O-N 2.78Å; L401-A403 VanDerWaalsContact C-N 3.32Å; L401-A403 PolarHBondContact O-N 3.19Å; L401-G404 PolarHBondContact O-N 2.71Å; L401-I405 HydrophobicContact CD1-CD1 4.1Å; L401-I405 HydrophobicContact CD1-CG1 4.43Å; L401-I405 HydrophobicContact CG-CD1 4.26Å; L401-I405 WeakPolarHBondContact O-CG1 3.37Å; L401-I405 PolarHBondContact O-N 3.44Å; L401-I405 VanDerWaalsContact O-N 3.1Å
402	F	91.3	Very high	89.4	Confident	47 Å²	47	20 Å²	20	21%	0.206	10%	0.101	C	C	.	.	H	α-helix	trans	-65.7	-34.1	176.2	-86.4	-83.4	0	0	0	112.6	A348 M398 V406	A348-F402 HydrophobicContact CB-CD1 4.21Å; A348-F402 HydrophobicContact CB-CD2 3.52Å; A348-F402 HydrophobicContact CB-CE1 4.21Å; A348-F402 HydrophobicContact CB-CE2 3.51Å; A348-F402 HydrophobicContact CB-CG 3.88Å; A348-F402 HydrophobicContact CB-CZ 3.88Å; M398-F402 HydrophobicContact CE-CE2 3.98Å; M398-F402 HydrophobicContact CG-CD2 4.2Å; M398-F402 HydrophobicContact CG-CE2 4.35Å; M398-F402 PolarHBondContact O-N 2.78Å; M398-F402 HydrophobicContact SD-CD2 3.69Å; M398-F402 HydrophobicContact SD-CE2 3.56Å; M398-F402 VanDerWaalsContact SD-CE2 3.56Å; F402-V406 WeakPolarHBondContact O-CB 3.37Å; F402-V406 VanDerWaalsContact O-CG2 3.24Å; F402-V406 WeakPolarHBondContact O-CG2 3.21Å; F402-V406 PolarHBondContact O-N 3.44Å; F402-V406 VanDerWaalsContact O-N 3.08Å
403	A	94	Very high	89	Confident	0 Å²	0	17.4 Å²	17.4	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-63.4	-43.9	172.6	0	0	0	0	0	112.1	G351 P385 S399 I400 L401 V406 M407	G351-A403 WeakPolarHBondContact O-CA 3.26Å; G351-A403 WeakPolarHBondContact O-CB 3.29Å; P385-A403 HydrophobicContact CB-CB 3.8Å; P385-A403 HydrophobicContact CG-CB 3.62Å; S399-A403 VanDerWaalsContact O-CB 3.3Å; S399-A403 WeakPolarHBondContact O-CB 3.41Å; S399-A403 PolarHBondContact O-N 2.79Å; I400-A403 WeakPolarHBondContact O-CB 3.34Å; I400-A403 PolarHBondContact O-N 2.98Å; L401-A403 VanDerWaalsContact C-N 3.32Å; L401-A403 PolarHBondContact O-N 3.19Å; A403-V406 PolarHBondContact O-N 2.99Å; A403-M407 VanDerWaalsContact O-CB 3.25Å; A403-M407 WeakPolarHBondContact O-CB 3.34Å; A403-M407 WeakPolarHBondContact O-CG 3.4Å; A403-M407 PolarHBondContact O-N 3.25Å
404	G	91.9	Very high	88.9	Confident	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-60.9	-46	177.7	0	0	0	0	0	113	F211 G214 I400 L401 V406 M407 S408	F211-G404 VanDerWaalsContact CE2-CA 3.43Å; G214-G404 CarbonylContact O-C 3.57Å; I400-G404 PolarHBondContact O-N 2.85Å; L401-G404 PolarHBondContact O-N 2.71Å; G404-V406 PolarHBondContact O-N 3.21Å; G404-M407 PolarHBondContact O-N 2.98Å; G404-S408 WeakPolarHBondContact O-CB 3.38Å; G404-S408 PolarHBondContact O-N 3.15Å
405	I	87.9	Confident	88.6	Confident	16 Å²	16	8.8 Å²	8.8	8%	0.082	4%	0.043	C	C	.	.	H	α-helix	trans	-59	-47	175.7	-64.7	169	0	0	0	110.8	G214 L217 F223 L401 S408 H409	G214-I405 VanDerWaalsContact O-CA 3.31Å; G214-I405 WeakPolarHBondContact O-CA 3.34Å; G214-I405 PolarHBondContact O-N 2.96Å; L217-I405 HydrophobicContact CD2-CD1 4.07Å; L217-I405 HydrophobicContact CD2-CG1 3.8Å; L217-I405 HydrophobicContact CD2-CG2 4.48Å; F223-I405 HydrophobicContact CZ-CG2 3.92Å; L401-I405 HydrophobicContact CD1-CD1 4.1Å; L401-I405 HydrophobicContact CD1-CG1 4.43Å; L401-I405 HydrophobicContact CG-CD1 4.26Å; L401-I405 WeakPolarHBondContact O-CG1 3.37Å; L401-I405 PolarHBondContact O-N 3.44Å; L401-I405 VanDerWaalsContact O-N 3.1Å; I405-S408 PolarHBondContact O-N 3.39Å; I405-H409 PolarHBondContact O-N 3.38Å
406	V	89.8	Confident	88.3	Confident	15 Å²	15	9 Å²	9	9%	0.091	4%	0.044	C	C	.	.	H	α-helix	trans	-71.9	-35.3	-179	171.1	0	0	0	0	111.8	T352 L356 F402 A403 G404 H409 Y410	T352-V406 HydrophobicContact CG2-CG2 4.15Å; L356-V406 HydrophobicContact CD2-CG1 3.78Å; L356-V406 HydrophobicContact CG-CG1 3.87Å; F402-V406 WeakPolarHBondContact O-CB 3.37Å; F402-V406 VanDerWaalsContact O-CG2 3.24Å; F402-V406 WeakPolarHBondContact O-CG2 3.21Å; F402-V406 PolarHBondContact O-N 3.44Å; F402-V406 VanDerWaalsContact O-N 3.08Å; A403-V406 PolarHBondContact O-N 2.99Å; G404-V406 PolarHBondContact O-N 3.21Å; V406-H409 PolarHBondContact O-N 2.95Å; V406-Y410 HydrophobicContact CG1-CD2 3.83Å; V406-Y410 HydrophobicContact CG1-CE2 4.26Å; V406-Y410 WeakPolarHBondContact O-CD2 3.45Å; V406-Y410 PolarHBondContact O-N 3.3Å
407	M	90.2	Very high	87.8	Confident	1 Å²	1	12 Å²	12	1%	0.005	6%	0.064	C	C	.	.	I	π-helix	trans	-70.1	-34.5	174.9	-73.7	174.6	66.3	0	0	112.2	F211 Y215 M378 F381 A403 G404 T411 H412	F211-M407 HydrophobicContact CE2-CE 4.39Å; F211-M407 HydrophobicContact CE2-SD 3.81Å; F211-M407 HydrophobicContact CZ-CB 4.39Å; F211-M407 HydrophobicContact CZ-CE 3.83Å; F211-M407 HydrophobicContact CZ-SD 3.81Å; Y215-M407 HydrophobicContact CD2-CB 4.32Å; Y215-M407 HydrophobicContact CE2-CB 4.25Å; M378-M407 HydrophobicContact CE-CE 3.57Å; M378-M407 HydrophobicContact SD-CE 3.81Å; F381-M407 HydrophobicContact CB-CE 3.69Å; F381-M407 HydrophobicContact CB-SD 4.21Å; A403-M407 VanDerWaalsContact O-CB 3.25Å; A403-M407 WeakPolarHBondContact O-CB 3.34Å; A403-M407 WeakPolarHBondContact O-CG 3.4Å; A403-M407 PolarHBondContact O-N 3.25Å; G404-M407 PolarHBondContact O-N 2.98Å; M407-T411 CarbonylContact O-C 3.5Å; M407-T411 WeakPolarHBondContact O-CA 3.18Å; M407-T411 VanDerWaalsContact O-CB 3.28Å; M407-T411 WeakPolarHBondContact O-CB 3.29Å; M407-T411 PolarHBondContact O-N 3.27Å; M407-H412 PolarHBondContact O-N 3.47Å
408	S	86.7	Confident	87.4	Confident	7 Å²	7	16 Å²	16	5%	0.049	8%	0.084	C	C	.	.	I	π-helix	trans	-68.6	-38.3	171.2	-175.5	0	0	0	0	112.1	Y215 K219 G404 I405 H412	Y215-S408 VanDerWaalsContact O-CB 3.23Å; Y215-S408 WeakPolarHBondContact O-CB 3.33Å; Y215-S408 PolarHBondContact O-OG 2.89Å; K219-S408 WeakPolarHBondContact CE-O 3.4Å; K219-S408 WeakPolarHBondContact CE-OG 3.33Å; G404-S408 WeakPolarHBondContact O-CB 3.38Å; G404-S408 PolarHBondContact O-N 3.15Å; I405-S408 PolarHBondContact O-N 3.39Å; S408-H412 WeakPolarHBondContact O-CB 3.4Å
409	H	83	Confident	87.2	Confident	19 Å²	19	16 Å²	16	9%	0.088	8%	0.084	C	C	.	.	I	π-helix	trans	-73.5	-42.5	179.7	-166.9	-94	0	0	0	113.9	F223 I405 V406 H413 D607	F223-H409 AromaticContact CE2-CD2 3.91Å; I405-H409 PolarHBondContact O-N 3.38Å; V406-H409 PolarHBondContact O-N 2.95Å; H409-H413 PolarHBondContact O-CE1 2.98Å; H409-H413 PolarHBondContact O-ND1 3.25Å; H409-D607 IonicContact CE1-OD1 2.58Å; H409-D607 IonicContact CE1-OD2 3.49Å; H409-D607 PolarHBondContact CE1-OD2 3.37Å; H409-D607 IonicContact ND1-OD2 3.51Å; H409-D607 IonicContact NE2-OD2 2.93Å
410	Y	85.1	Confident	86.8	Confident	16 Å²	16	17.7 Å²	17.7	6%	0.063	9%	0.092	C	C	.	.	I	π-helix	trans	-111.4	-51.7	-174.5	-58.1	-78.8	0	0	0	113.2	L356 V406 H412 H413 D607 L611 F615 T616	L356-Y410 HydrophobicContact CD2-CD2 3.75Å; L356-Y410 HydrophobicContact CD2-CE2 3.85Å; L356-Y410 HydrophobicContact CD2-CG 4.3Å; V406-Y410 HydrophobicContact CG1-CD2 3.83Å; V406-Y410 HydrophobicContact CG1-CE2 4.26Å; V406-Y410 WeakPolarHBondContact O-CD2 3.45Å; V406-Y410 PolarHBondContact O-N 3.3Å; Y410-H412 PolarHBondContact O-N 2.96Å; Y410-H413 PolarHBondContact O-N 3.43Å; Y410-D607 WeakPolarHBondContact CE1-OD1 3.4Å; Y410-D607 PolarHBondContact OH-OD1 3.45Å; Y410-L611 HydrophobicContact CE1-CB 4.15Å; Y410-F615 HydrophobicContact CD1-CB 3.65Å; Y410-F615 HydrophobicContact CD1-CD2 4.41Å; Y410-F615 HydrophobicContact CD1-CG 4.35Å; Y410-F615 HydrophobicContact CE1-CB 4.35Å; Y410-F615 HydrophobicContact CE1-CD2 4.33Å; Y410-F615 HydrophobicContact CG-CB 4.02Å; Y410-T616 HydrophobicContact CD1-CG2 4.49Å
411	T	87.8	Confident	86.3	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	11%	0.107	C	C	.	.	I	π-helix	trans	-66.6	-38	-173.5	-48.2	0	0	0	0	112.8	G355 A359 L362 M378 M407 H413 N414	G355-T411 PolarHBondContact O-OG1 3.5Å; A359-T411 WeakPolarHBondContact CA-OG1 3.48Å; A359-T411 WeakPolarHBondContact CB-OG1 3.42Å; A359-T411 PolarHBondContact N-OG1 2.93Å; L362-T411 HydrophobicContact CD1-CG2 3.42Å; L362-T411 VanDerWaalsContact CD1-CG2 3.42Å; M378-T411 HydrophobicContact CE-CG2 4.31Å; M378-T411 HydrophobicContact SD-CG2 3.49Å; M378-T411 WeakPolarHBondContact SD-CG2 3.38Å; M407-T411 CarbonylContact O-C 3.5Å; M407-T411 WeakPolarHBondContact O-CA 3.18Å; M407-T411 VanDerWaalsContact O-CB 3.28Å; M407-T411 WeakPolarHBondContact O-CB 3.29Å; M407-T411 PolarHBondContact O-N 3.27Å; T411-H413 VanDerWaalsContact C-N 3.26Å; T411-H413 PolarHBondContact O-N 3.45Å; T411-N414 WeakPolarHBondContact O-CB 3.14Å; T411-N414 PolarHBondContact O-N 3.05Å
412	H	85	Confident	86.1	Confident	9 Å²	9	23.8 Å²	23.8	4%	0.042	12%	0.124	C	C	.	.	G	3₁₀ helix	trans	-53.8	-42.2	-178.9	-169.5	74.3	0	0	0	112.5	Y215 M407 S408 Y410 N414 L415 Q420 Q424	Y215-H412 AromaticContact CE1-ND1 3.99Å; Y215-H412 AromaticContact CZ-ND1 3.59Å; Y215-H412 PolarHBondContact OH-ND1 2.91Å; M407-H412 PolarHBondContact O-N 3.47Å; S408-H412 WeakPolarHBondContact O-CB 3.4Å; Y410-H412 PolarHBondContact O-N 2.96Å; H412-N414 PolarHBondContact O-N 2.82Å; H412-L415 WeakPolarHBondContact O-CB 3.36Å; H412-L415 PolarHBondContact O-N 3.39Å; H412-Q420 PolarHBondContact O-NE2 3.37Å; H412-Q424 PolarHBondContact CE1-NE2 3.38Å; H412-Q424 PolarHBondContact NE2-NE2 2.81Å
413	H	82.1	Confident	85.9	Confident	29 Å²	29	21.5 Å²	21.5	13%	0.134	11%	0.114	C	C	.	.	G	3₁₀ helix	trans	-72.9	-9.4	-179.8	-52.1	103.2	0	0	0	114	H409 Y410 T411 Q593 T616	H409-H413 PolarHBondContact O-CE1 2.98Å; H409-H413 PolarHBondContact O-ND1 3.25Å; Y410-H413 PolarHBondContact O-N 3.43Å; T411-H413 VanDerWaalsContact C-N 3.26Å; T411-H413 PolarHBondContact O-N 3.45Å; H413-Q593 PolarHBondContact NE2-NE2 3.31Å; H413-T616 HydrophobicContact CB-CG2 3.98Å
414	N	83.9	Confident	85.5	Confident	6 Å²	6	23.9 Å²	23.9	3%	0.032	13%	0.125	C	C	.	.	G	3₁₀ helix	trans	-90.8	-15.9	173.2	-69.2	-25.9	0	0	0	113.4	A359 L362 T411 H412 F615 T616 R617	A359-N414 PolarHBondContact O-ND2 3.11Å; L362-N414 HydrophobicContact CB-CB 4.34Å; T411-N414 WeakPolarHBondContact O-CB 3.14Å; T411-N414 PolarHBondContact O-N 3.05Å; H412-N414 PolarHBondContact O-N 2.82Å; N414-F615 PolarHBondContact ND2-O 3.2Å; N414-T616 VanDerWaalsContact OD1-CA 3.25Å; N414-T616 WeakPolarHBondContact OD1-CA 3.24Å; N414-R617 PolarHBondContact OD1-N 3.37Å
415	L	83.6	Confident	85.3	Confident	6 Å²	6	25.4 Å²	25.4	3%	0.031	13%	0.132	C	C	.	.	S	Bend	trans	-75.2	156.5	-177.1	-61.6	172.8	0	0	0	112.3	L362 E374 M378 H412 T419 Q420	L362-L415 HydrophobicContact CD1-CD2 4.01Å; E374-L415 HydrophobicContact CG-CD2 3.72Å; E374-L415 VanDerWaalsContact OE1-CA 3.31Å; E374-L415 WeakPolarHBondContact OE1-CA 3.4Å; M378-L415 HydrophobicContact CE-CD1 4.02Å; M378-L415 HydrophobicContact CG-CD1 4.15Å; M378-L415 HydrophobicContact CG-CD2 3.62Å; M378-L415 HydrophobicContact SD-CD1 4.11Å; M378-L415 HydrophobicContact SD-CD2 3.9Å; M378-L415 HydrophobicContact SD-CG 4.44Å; H412-L415 WeakPolarHBondContact O-CB 3.36Å; H412-L415 PolarHBondContact O-N 3.39Å; L415-T419 HydrophobicContact CD1-CG2 4.34Å; L415-T419 HydrophobicContact CD2-CG2 4.09Å; L415-Q420 HydrophobicContact CB-CG 3.77Å; L415-Q420 HydrophobicContact CD1-CG 4.46Å
416	S	82.9	Confident	85.4	Confident	9 Å²	9	26.8 Å²	26.8	6%	0.063	14%	0.141	C	C	.	.			trans	-64.6	148.3	163.5	70.1	0	0	0	0	111.4	E374 I418 T419 Q420	E374-S416 PolarHBondContact OE1-N 3.31Å; E374-S416 WeakPolarHBondContact OE2-CB 2.98Å; E374-S416 PolarHBondContact OE2-N 2.9Å; E374-S416 PolarHBondContact OE2-OG 2.89Å; S416-I418 PolarHBondContact O-N 3.3Å; S416-T419 CarbonylContact O-C 3.45Å; S416-T419 PolarHBondContact O-N 2.83Å; S416-T419 PolarHBondContact OG-N 2.99Å; S416-T419 PolarHBondContact OG-OG1 3.5Å; S416-T419 VanDerWaalsContact OG-OG1 3.07Å; S416-Q420 WeakPolarHBondContact O-CG 3.44Å; S416-Q420 PolarHBondContact O-N 3.06Å
417	P	79.5	Confident	85.4	Confident	64 Å²	64	26.7 Å²	26.7	42%	0.416	14%	0.14	S	C	.	.	H	α-helix	trans	-57.5	-33.4	180	-27.8	35.9	0	0	0	114.1	Q420 I421	P417-Q420 PolarHBondContact O-N 3.15Å; P417-I421 WeakPolarHBondContact O-CG1 3.3Å; P417-I421 PolarHBondContact O-N 3.31Å; P417-I421 VanDerWaalsContact O-N 3.15Å
418	I	81.3	Confident	85.1	Confident	90 Å²	90	30.1 Å²	30.1	46%	0.462	15%	0.153	S	C	.	.	H	α-helix	trans	-62.6	-46.9	175	-59.9	174.1	0	0	0	109.9	P371 S416 L422	P371-I418 HydrophobicContact CB-CG2 4.42Å; S416-I418 PolarHBondContact O-N 3.3Å; I418-L422 VanDerWaalsContact O-CB 3.3Å; I418-L422 WeakPolarHBondContact O-CB 3.3Å; I418-L422 PolarHBondContact O-N 3.45Å
419	T	86.5	Confident	85	Confident	0 Å²	0	33 Å²	33	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-71	-30.4	177.3	-56.8	0	0	0	0	112.6	E374 F375 L415 S416 M423	E374-T419 HydrophobicContact CB-CG2 4.36Å; E374-T419 HydrophobicContact CG-CG2 4.04Å; E374-T419 WeakPolarHBondContact OE2-CB 3.5Å; E374-T419 PolarHBondContact OE2-OG1 3.1Å; F375-T419 HydrophobicContact CB-CG2 4.05Å; L415-T419 HydrophobicContact CD1-CG2 4.34Å; L415-T419 HydrophobicContact CD2-CG2 4.09Å; S416-T419 CarbonylContact O-C 3.45Å; S416-T419 PolarHBondContact O-N 2.83Å; S416-T419 PolarHBondContact OG-N 2.99Å; S416-T419 PolarHBondContact OG-OG1 3.5Å; S416-T419 VanDerWaalsContact OG-OG1 3.07Å; T419-M423 WeakPolarHBondContact O-CB 3.41Å; T419-M423 PolarHBondContact O-N 3.13Å
420	Q	85	Confident	85.3	Confident	36 Å²	36	34.9 Å²	34.9	17%	0.168	18%	0.183	C	C	.	.	H	α-helix	trans	-59.5	-52	173.2	-72.3	174.6	-21.3	0	0	111.4	H412 L415 S416 P417 M423 Q424	H412-Q420 PolarHBondContact O-NE2 3.37Å; L415-Q420 HydrophobicContact CB-CG 3.77Å; L415-Q420 HydrophobicContact CD1-CG 4.46Å; S416-Q420 WeakPolarHBondContact O-CG 3.44Å; S416-Q420 PolarHBondContact O-N 3.06Å; P417-Q420 PolarHBondContact O-N 3.15Å; Q420-M423 PolarHBondContact O-N 2.95Å; Q420-Q424 WeakPolarHBondContact O-CG 3.47Å; Q420-Q424 PolarHBondContact O-N 3.38Å; Q420-Q424 VanDerWaalsContact O-N 3.14Å
421	I	83.1	Confident	85.4	Confident	60 Å²	60	34.3 Å²	34.3	31%	0.308	18%	0.182	S	C	.	.	H	α-helix	trans	-64.3	-47.9	178.6	-62.7	167.5	0	0	0	110.1	P417 M423 Q424 Q425	P417-I421 WeakPolarHBondContact O-CG1 3.3Å; P417-I421 PolarHBondContact O-N 3.31Å; P417-I421 VanDerWaalsContact O-N 3.15Å; I421-M423 PolarHBondContact O-N 3.4Å; I421-Q424 PolarHBondContact O-N 2.91Å; I421-Q425 HydrophobicContact CG2-CG 4.28Å; I421-Q425 WeakPolarHBondContact O-CG 3.49Å; I421-Q425 PolarHBondContact O-N 3.32Å
422	L	87.1	Confident	85.1	Confident	69 Å²	69	36.6 Å²	36.6	36%	0.361	19%	0.192	S	C	.	.	H	α-helix	trans	-57.1	-46.7	178.2	179.9	62.6	0	0	0	111.8	F375 I418 Q424 Q425 T426	F375-L422 HydrophobicContact CB-CD2 4.12Å; F375-L422 HydrophobicContact CD1-CD2 4.36Å; F375-L422 HydrophobicContact CD2-CD2 3.85Å; F375-L422 HydrophobicContact CD2-CG 3.9Å; F375-L422 HydrophobicContact CE2-CD2 4.41Å; F375-L422 HydrophobicContact CE2-CG 4.08Å; F375-L422 HydrophobicContact CG-CD2 3.83Å; F375-L422 HydrophobicContact CG-CG 4.37Å; I418-L422 VanDerWaalsContact O-CB 3.3Å; I418-L422 WeakPolarHBondContact O-CB 3.3Å; I418-L422 PolarHBondContact O-N 3.45Å; L422-Q424 PolarHBondContact O-N 2.97Å; L422-Q425 PolarHBondContact O-N 3.43Å; L422-T426 WeakPolarHBondContact O-CB 3.39Å; L422-T426 PolarHBondContact O-N 3.03Å; L422-T426 PolarHBondContact O-OG1 3.25Å; L422-T426 VanDerWaalsContact O-OG1 3.1Å
423	M	88.3	Confident	85	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-62	-46.8	-179.6	-167.5	72.8	-177.3	0	0	111.7	F211 Y215 F375 M378 I379 T419 Q420 I421 L427	F211-M423 HydrophobicContact CE1-CE 4Å; Y215-M423 HydrophobicContact CE1-CG 3.96Å; F375-M423 HydrophobicContact CD2-SD 3.89Å; F375-M423 HydrophobicContact CE2-SD 3.73Å; M378-M423 HydrophobicContact CB-CE 3.77Å; M378-M423 HydrophobicContact CB-SD 3.65Å; M378-M423 HydrophobicContact CE-CE 3.89Å; M378-M423 HydrophobicContact CE-CG 4.18Å; M378-M423 HydrophobicContact CE-SD 4.29Å; M378-M423 HydrophobicContact CG-SD 4.42Å; I379-M423 HydrophobicContact CD1-CE 3.89Å; I379-M423 HydrophobicContact CD1-SD 4.12Å; T419-M423 WeakPolarHBondContact O-CB 3.41Å; T419-M423 PolarHBondContact O-N 3.13Å; Q420-M423 PolarHBondContact O-N 2.95Å; I421-M423 PolarHBondContact O-N 3.4Å; M423-L427 HydrophobicContact CE-CD1 3.78Å; M423-L427 HydrophobicContact CE-CD2 3.99Å; M423-L427 HydrophobicContact CE-CG 3.94Å; M423-L427 HydrophobicContact CG-CD1 3.94Å; M423-L427 HydrophobicContact CG-CG 4.32Å; M423-L427 VanDerWaalsContact O-CB 3.26Å; M423-L427 WeakPolarHBondContact O-CB 3.42Å; M423-L427 WeakPolarHBondContact O-CG 3.41Å; M423-L427 PolarHBondContact O-N 3.26Å; M423-L427 HydrophobicContact SD-CD1 4.47Å; M423-L427 HydrophobicContact SD-CG 4.43Å
424	Q	85.5	Confident	85.1	Confident	49 Å²	49	39.1 Å²	39.1	23%	0.229	21%	0.206	C	C	.	.	H	α-helix	trans	-60.8	-47.7	177.8	-70.7	-178.1	9.2	0	0	111.7	Y215 H412 Q420 I421 L422 R428	Y215-Q424 HydrophobicContact CE1-CG 4.32Å; H412-Q424 PolarHBondContact CE1-NE2 3.38Å; H412-Q424 PolarHBondContact NE2-NE2 2.81Å; Q420-Q424 WeakPolarHBondContact O-CG 3.47Å; Q420-Q424 PolarHBondContact O-N 3.38Å; Q420-Q424 VanDerWaalsContact O-N 3.14Å; I421-Q424 PolarHBondContact O-N 2.91Å; L422-Q424 PolarHBondContact O-N 2.97Å; Q424-R428 VanDerWaalsContact O-CB 3.27Å; Q424-R428 WeakPolarHBondContact O-CB 3.34Å; Q424-R428 PolarHBondContact O-N 3.25Å; Q424-R428 VanDerWaalsContact O-N 3.08Å
425	Q	86.7	Confident	85	Confident	33 Å²	33	40.2 Å²	40.2	15%	0.154	21%	0.211	C	C	.	.	H	α-helix	trans	-71	-40.6	-176.3	-62.5	-64.7	-4.6	0	0	112.3	I421 L422 T429 M573	I421-Q425 HydrophobicContact CG2-CG 4.28Å; I421-Q425 WeakPolarHBondContact O-CG 3.49Å; I421-Q425 PolarHBondContact O-N 3.32Å; L422-Q425 PolarHBondContact O-N 3.43Å; Q425-T429 WeakPolarHBondContact O-CB 3.34Å; Q425-T429 PolarHBondContact O-N 3.11Å; Q425-T429 PolarHBondContact O-OG1 2.91Å; Q425-M573 VanDerWaalsContact OE1-CE 3.26Å
426	T	89.6	Confident	84.9	Confident	44 Å²	44	40.2 Å²	40.2	27%	0.27	21%	0.211	S	C	.	.	H	α-helix	trans	-68.9	-44.8	177.4	-57.8	0	0	0	0	111.7	F375 L422 R428 T429 V430	F375-T426 HydrophobicContact CE2-CG2 4.45Å; F375-T426 HydrophobicContact CZ-CG2 3.85Å; L422-T426 WeakPolarHBondContact O-CB 3.39Å; L422-T426 PolarHBondContact O-N 3.03Å; L422-T426 PolarHBondContact O-OG1 3.25Å; L422-T426 VanDerWaalsContact O-OG1 3.1Å; T426-R428 PolarHBondContact O-N 2.95Å; T426-T429 PolarHBondContact O-N 3.38Å; T426-V430 HydrophobicContact CG2-CG2 4.21Å; T426-V430 WeakPolarHBondContact O-CG2 3.29Å; T426-V430 PolarHBondContact O-N 2.97Å
427	L	90.3	Very high	84.7	Confident	14 Å²	14	40.7 Å²	40.7	7%	0.073	21%	0.214	C	C	.	.	H	α-helix	trans	-57.8	-48.5	175.8	-74.7	176.3	0	0	0	111.4	F211 E212 Y215 M423 T429 V430 A431	F211-L427 HydrophobicContact CD1-CD1 3.87Å; F211-L427 HydrophobicContact CD1-CD2 3.68Å; F211-L427 HydrophobicContact CD1-CG 4.43Å; F211-L427 HydrophobicContact CE1-CD1 3.73Å; F211-L427 HydrophobicContact CE1-CD2 4.1Å; E212-L427 HydrophobicContact CB-CB 4.36Å; E212-L427 HydrophobicContact CG-CB 3.88Å; Y215-L427 HydrophobicContact CD1-CD1 3.47Å; Y215-L427 VanDerWaalsContact CD1-CD1 3.47Å; Y215-L427 HydrophobicContact CE1-CD1 3.87Å; Y215-L427 HydrophobicContact CG-CD1 3.85Å; M423-L427 HydrophobicContact CE-CD1 3.78Å; M423-L427 HydrophobicContact CE-CD2 3.99Å; M423-L427 HydrophobicContact CE-CG 3.94Å; M423-L427 HydrophobicContact CG-CD1 3.94Å; M423-L427 HydrophobicContact CG-CG 4.32Å; M423-L427 VanDerWaalsContact O-CB 3.26Å; M423-L427 WeakPolarHBondContact O-CB 3.42Å; M423-L427 WeakPolarHBondContact O-CG 3.41Å; M423-L427 PolarHBondContact O-N 3.26Å; M423-L427 HydrophobicContact SD-CD1 4.47Å; M423-L427 HydrophobicContact SD-CG 4.43Å; L427-T429 VanDerWaalsContact C-N 3.33Å; L427-T429 PolarHBondContact O-N 3.22Å; L427-V430 PolarHBondContact O-N 3.37Å; L427-A431 VanDerWaalsContact O-CB 3.31Å; L427-A431 WeakPolarHBondContact O-CB 3.25Å; L427-A431 PolarHBondContact O-N 2.98Å
428	R	84.2	Confident	84.8	Confident	73 Å²	73	38.3 Å²	38.3	28%	0.275	20%	0.198	S	C	.	.	H	α-helix	trans	-59.9	-41.9	178.5	-171	169.1	-63.1	147	3	112.8	E212 Q424 T426 F432 M573	E212-R428 HydrophobicContact CG-CB 4.46Å; E212-R428 IonicContact OE1-NE 2.78Å; E212-R428 PolarHBondContact OE1-NE 3.38Å; E212-R428 IonicContact OE1-NH2 2.57Å; Q424-R428 VanDerWaalsContact O-CB 3.27Å; Q424-R428 WeakPolarHBondContact O-CB 3.34Å; Q424-R428 PolarHBondContact O-N 3.25Å; Q424-R428 VanDerWaalsContact O-N 3.08Å; T426-R428 PolarHBondContact O-N 2.95Å; R428-F432 WeakPolarHBondContact O-CB 3.43Å; R428-F432 PolarHBondContact O-N 3.43Å; R428-M573 HydrophobicContact CG-CE 4.12Å; R428-M573 HydrophobicContact CG-SD 4.1Å
429	T	85.1	Confident	84.8	Confident	66 Å²	66	34.5 Å²	34.5	41%	0.405	18%	0.179	S	C	.	.	H	α-helix	trans	-65.8	-45.5	177.8	-55.6	0	0	0	0	111.4	Q425 T426 L427 F432 M433	Q425-T429 WeakPolarHBondContact O-CB 3.34Å; Q425-T429 PolarHBondContact O-N 3.11Å; Q425-T429 PolarHBondContact O-OG1 2.91Å; T426-T429 PolarHBondContact O-N 3.38Å; L427-T429 VanDerWaalsContact C-N 3.33Å; L427-T429 PolarHBondContact O-N 3.22Å; T429-F432 PolarHBondContact O-N 3.42Å; T429-M433 HydrophobicContact CG2-SD 4.48Å; T429-M433 WeakPolarHBondContact O-CG 3.47Å; T429-M433 PolarHBondContact O-N 2.96Å
430	V	88.5	Confident	84.5	Confident	59 Å²	59	35 Å²	35	36%	0.358	18%	0.183	S	C	.	.	H	α-helix	trans	-65.9	-46	178.4	175.5	0	0	0	0	111	P208 T426 L427 F432 M433 C434	P208-V430 HydrophobicContact CB-CG1 3.67Å; P208-V430 HydrophobicContact CG-CG1 4.1Å; T426-V430 HydrophobicContact CG2-CG2 4.21Å; T426-V430 WeakPolarHBondContact O-CG2 3.29Å; T426-V430 PolarHBondContact O-N 2.97Å; L427-V430 PolarHBondContact O-N 3.37Å; V430-F432 PolarHBondContact O-N 3.17Å; V430-M433 PolarHBondContact O-N 3.21Å; V430-C434 WeakPolarHBondContact O-CB 3.22Å; V430-C434 PolarHBondContact O-N 3.43Å; V430-C434 PolarHBondContact O-SG 3.39Å
431	A	86.9	Confident	84.1	Confident	4 Å²	4	36.2 Å²	36.2	3%	0.033	19%	0.187	C	C	.	.	H	α-helix	trans	-60.2	-44.6	176.5	0	0	0	0	0	112	E212 L427 M433 C434 E435	E212-A431 HydrophobicContact CB-CB 3.6Å; E212-A431 HydrophobicContact CG-CB 3.93Å; L427-A431 VanDerWaalsContact O-CB 3.31Å; L427-A431 WeakPolarHBondContact O-CB 3.25Å; L427-A431 PolarHBondContact O-N 2.98Å; A431-M433 PolarHBondContact O-N 2.9Å; A431-C434 PolarHBondContact O-N 3.35Å; A431-E435 WeakPolarHBondContact O-CB 3.32Å; A431-E435 PolarHBondContact O-N 2.87Å
432	F	82.4	Confident	84.1	Confident	49 Å²	49	33.3 Å²	33.3	22%	0.215	17%	0.173	C	C	.	.	H	α-helix	trans	-61.2	-40.6	174.8	171.6	-99.9	0	0	0	112.9	V151 R428 T429 V430 T436	V151-F432 HydrophobicContact CG1-CZ 4.15Å; R428-F432 WeakPolarHBondContact O-CB 3.43Å; R428-F432 PolarHBondContact O-N 3.43Å; T429-F432 PolarHBondContact O-N 3.42Å; V430-F432 PolarHBondContact O-N 3.17Å; F432-T436 VanDerWaalsContact O-CB 3.31Å; F432-T436 WeakPolarHBondContact O-CB 3.24Å; F432-T436 PolarHBondContact O-N 2.99Å; F432-T436 PolarHBondContact O-OG1 2.85Å
433	M	82.1	Confident	83.8	Confident	77 Å²	77	30 Å²	30	38%	0.379	16%	0.155	S	C	.	.	H	α-helix	trans	-64.8	-43.4	173.4	-73	-178.5	71.4	0	0	111.4	V144 I148 T429 V430 A431 T436 C437	V144-M433 HydrophobicContact CG1-CE 4.48Å; I148-M433 HydrophobicContact CD1-CE 4.28Å; T429-M433 HydrophobicContact CG2-SD 4.48Å; T429-M433 WeakPolarHBondContact O-CG 3.47Å; T429-M433 PolarHBondContact O-N 2.96Å; V430-M433 PolarHBondContact O-N 3.21Å; A431-M433 PolarHBondContact O-N 2.9Å; M433-T436 PolarHBondContact O-N 3.49Å; M433-C437 WeakPolarHBondContact O-CB 3.46Å; M433-C437 PolarHBondContact O-N 3.43Å; M433-C437 PolarHBondContact O-SG 3.37Å
434	C	85.6	Confident	83.3	Confident	13 Å²	13	30.8 Å²	30.8	9%	0.088	16%	0.159	C	C	.	.	H	α-helix	trans	-63.5	-47.1	176.3	-68.4	0	0	0	0	112.2	L205 I209 V430 A431 T436 C437 V438	L205-C434 WeakPolarHBondContact O-CB 3.39Å; I209-C434 HydrophobicContact CD1-CB 3.74Å; I209-C434 HydrophobicContact CG1-CB 3.59Å; V430-C434 WeakPolarHBondContact O-CB 3.22Å; V430-C434 PolarHBondContact O-N 3.43Å; V430-C434 PolarHBondContact O-SG 3.39Å; A431-C434 PolarHBondContact O-N 3.35Å; C434-T436 VanDerWaalsContact C-N 3.32Å; C434-T436 PolarHBondContact O-N 3.04Å; C434-C437 PolarHBondContact O-N 2.91Å; C434-V438 VanDerWaalsContact O-CB 3.29Å; C434-V438 WeakPolarHBondContact O-CB 3.37Å; C434-V438 WeakPolarHBondContact O-CG2 3.34Å; C434-V438 PolarHBondContact O-N 2.94Å
435	E	80.8	Confident	82.9	Confident	30 Å²	30	28.7 Å²	28.7	14%	0.14	15%	0.15	C	C	.	.	H	α-helix	trans	-52.4	-49.9	171.4	-79.5	-178	-158.2	0	0	110.3	I209 A431 V438 F439 K569	I209-E435 HydrophobicContact CD1-CG 4.25Å; I209-E435 HydrophobicContact CG1-CG 4.39Å; I209-E435 HydrophobicContact CG2-CG 4.34Å; A431-E435 WeakPolarHBondContact O-CB 3.32Å; A431-E435 PolarHBondContact O-N 2.87Å; E435-V438 PolarHBondContact O-N 2.94Å; E435-F439 HydrophobicContact CB-CD2 4.48Å; E435-F439 HydrophobicContact CB-CE2 4.36Å; E435-F439 WeakPolarHBondContact O-CD2 3.45Å; E435-F439 PolarHBondContact O-N 3.45Å; E435-K569 IonicContact OE1-NZ 3.23Å; E435-K569 PolarHBondContact OE1-NZ 2.9Å; E435-K569 IonicContact OE2-NZ 3.91Å; E435-K569 PolarHBondContact OE2-NZ 3.23Å
436	T	80.5	Confident	82.6	Confident	6 Å²	6	29 Å²	29	4%	0.037	15%	0.152	C	C	.	.	H	α-helix	trans	-62.2	-47.7	-178.4	-60.1	0	0	0	0	112	C147 V168 F432 M433 C434 V438 F439 A440	C147-T436 HydrophobicContact CB-CG2 3.93Å; V168-T436 HydrophobicContact CG1-CG2 4.04Å; V168-T436 WeakPolarHBondContact CG1-O 3.5Å; V168-T436 HydrophobicContact CG2-CG2 4.2Å; F432-T436 VanDerWaalsContact O-CB 3.31Å; F432-T436 WeakPolarHBondContact O-CB 3.24Å; F432-T436 PolarHBondContact O-N 2.99Å; F432-T436 PolarHBondContact O-OG1 2.85Å; M433-T436 PolarHBondContact O-N 3.49Å; C434-T436 VanDerWaalsContact C-N 3.32Å; C434-T436 PolarHBondContact O-N 3.04Å; T436-V438 VanDerWaalsContact C-N 3.31Å; T436-V438 PolarHBondContact O-N 3.24Å; T436-F439 PolarHBondContact O-N 2.91Å; T436-A440 WeakPolarHBondContact O-CB 3.39Å; T436-A440 PolarHBondContact O-N 3.5Å
437	C	80.2	Confident	81.9	Confident	19 Å²	19	30.1 Å²	30.1	13%	0.128	15%	0.154	C	C	.	.	H	α-helix	trans	-57.5	-45.9	174.8	-69.3	0	0	0	0	111.3	V144 M433 C434 A440 F441	V144-C437 VanDerWaalsContact CG2-SG 3.53Å; M433-C437 WeakPolarHBondContact O-CB 3.46Å; M433-C437 PolarHBondContact O-N 3.43Å; M433-C437 PolarHBondContact O-SG 3.37Å; C434-C437 PolarHBondContact O-N 2.91Å; C437-A440 PolarHBondContact O-N 3.32Å; C437-F441 HydrophobicContact CB-CD2 4.39Å; C437-F441 HydrophobicContact CB-CE2 4Å; C437-F441 WeakPolarHBondContact O-CD2 3.29Å; C437-F441 VanDerWaalsContact O-CG 3.3Å; C437-F441 WeakPolarHBondContact O-CG 3.38Å; C437-F441 PolarHBondContact O-N 3.23Å
438	V	81.7	Confident	80.8	Confident	14 Å²	14	31 Å²	31	9%	0.085	16%	0.161	C	C	.	.	H	α-helix	trans	-64	-43	-178.3	164.3	0	0	0	0	112	F201 L205 C434 E435 T436 L442 A504	F201-V438 HydrophobicContact CD2-CG2 3.86Å; F201-V438 HydrophobicContact CE2-CB 4.45Å; F201-V438 HydrophobicContact CE2-CG1 3.89Å; F201-V438 HydrophobicContact CE2-CG2 3.63Å; L205-V438 HydrophobicContact CB-CG2 3.97Å; L205-V438 HydrophobicContact CD1-CG2 3.87Å; L205-V438 HydrophobicContact CG-CG2 4.48Å; C434-V438 VanDerWaalsContact O-CB 3.29Å; C434-V438 WeakPolarHBondContact O-CB 3.37Å; C434-V438 WeakPolarHBondContact O-CG2 3.34Å; C434-V438 PolarHBondContact O-N 2.94Å; E435-V438 PolarHBondContact O-N 2.94Å; T436-V438 VanDerWaalsContact C-N 3.31Å; T436-V438 PolarHBondContact O-N 3.24Å; V438-L442 PolarHBondContact O-N 3.41Å; V438-A504 HydrophobicContact CG1-CB 3.22Å
439	F	80.8	Confident	80	Confident	10 Å²	10	29.7 Å²	29.7	4%	0.044	16%	0.157	C	C	.	.	H	α-helix	trans	-66.8	-37.2	173.5	-75	-57.9	0	0	0	112.7	S165 V168 V169 D276 E435 T436 L442 G443 I536	S165-F439 WeakPolarHBondContact OG-CE2 3.41Å; V168-F439 HydrophobicContact CB-CB 4.19Å; V168-F439 HydrophobicContact CG1-CB 3.71Å; V169-F439 HydrophobicContact CG2-CB 3.93Å; V169-F439 HydrophobicContact CG2-CD1 3.83Å; V169-F439 HydrophobicContact CG2-CG 4.27Å; D276-F439 WeakPolarHBondContact OD2-CZ 3.49Å; E435-F439 HydrophobicContact CB-CD2 4.48Å; E435-F439 HydrophobicContact CB-CE2 4.36Å; E435-F439 WeakPolarHBondContact O-CD2 3.45Å; E435-F439 PolarHBondContact O-N 3.45Å; T436-F439 PolarHBondContact O-N 2.91Å; F439-L442 PolarHBondContact O-N 2.9Å; F439-G443 PolarHBondContact O-N 2.8Å; F439-G443 VanDerWaalsContact O-N 3.13Å; F439-I536 HydrophobicContact CD1-CD1 4.43Å; F439-I536 HydrophobicContact CE1-CD1 3.91Å
440	A	79.2	Confident	79.2	Confident	10 Å²	10	30.1 Å²	30.1	8%	0.083	16%	0.161	C	C	.	.	H	α-helix	trans	-65.7	-43.7	176.4	0	0	0	0	0	111.6	V168 T436 C437 L442 G443 L444	V168-A440 HydrophobicContact CG1-CB 4.03Å; T436-A440 WeakPolarHBondContact O-CB 3.39Å; T436-A440 PolarHBondContact O-N 3.5Å; C437-A440 PolarHBondContact O-N 3.32Å; A440-L442 VanDerWaalsContact C-N 3.35Å; A440-L442 PolarHBondContact O-N 2.86Å; A440-G443 PolarHBondContact O-N 3.48Å; A440-L444 PolarHBondContact O-N 2.87Å
441	F	78.1	Confident	78.4	Confident	61 Å²	61	29 Å²	29	27%	0.268	15%	0.152	S	C	.	.	H	α-helix	trans	-63.6	-37.7	174.5	-66.3	-48.6	0	0	0	112.4	F196 L205 C437 G443 L444 S445	F196-F441 HydrophobicContact CD2-CB 4.08Å; F196-F441 HydrophobicContact CD2-CD1 4.16Å; F196-F441 AromaticContact CD2-CD2 3.74Å; F196-F441 HydrophobicContact CD2-CD2 3.74Å; F196-F441 HydrophobicContact CD2-CE2 4.18Å; F196-F441 AromaticContact CD2-CG 3.74Å; F196-F441 HydrophobicContact CD2-CG 3.74Å; F196-F441 HydrophobicContact CE2-CB 4.13Å; F196-F441 AromaticContact CE2-CD2 3.35Å; F196-F441 HydrophobicContact CE2-CD2 3.35Å; F196-F441 AromaticContact CE2-CE2 3.82Å; F196-F441 HydrophobicContact CE2-CE2 3.82Å; F196-F441 AromaticContact CE2-CG 3.8Å; F196-F441 HydrophobicContact CE2-CG 3.8Å; F196-F441 HydrophobicContact CZ-CD2 4.35Å; L205-F441 HydrophobicContact CD1-CD2 4.35Å; L205-F441 HydrophobicContact CD1-CE2 4.11Å; C437-F441 HydrophobicContact CB-CD2 4.39Å; C437-F441 HydrophobicContact CB-CE2 4Å; C437-F441 WeakPolarHBondContact O-CD2 3.29Å; C437-F441 VanDerWaalsContact O-CG 3.3Å; C437-F441 WeakPolarHBondContact O-CG 3.38Å; C437-F441 PolarHBondContact O-N 3.23Å; F441-G443 VanDerWaalsContact C-N 3.33Å; F441-G443 PolarHBondContact O-N 3.27Å; F441-L444 HydrophobicContact CD1-CD2 4.4Å; F441-L444 PolarHBondContact O-N 3.47Å; F441-S445 WeakPolarHBondContact O-CB 3.45Å; F441-S445 PolarHBondContact O-N 3.39Å; F441-S445 PolarHBondContact O-OG 2.93Å
442	L	81.7	Confident	77.7	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-60.3	-41.9	173.9	-176.3	132.4	0	0	0	111.8	V169 V438 F439 A440 A504 Y507 V532	V169-L442 HydrophobicContact CG1-CD2 4.02Å; V169-L442 HydrophobicContact CG2-CD2 3.94Å; V438-L442 PolarHBondContact O-N 3.41Å; F439-L442 PolarHBondContact O-N 2.9Å; A440-L442 VanDerWaalsContact C-N 3.35Å; A440-L442 PolarHBondContact O-N 2.86Å; L442-A504 HydrophobicContact CD1-CB 3.94Å; L442-Y507 HydrophobicContact CB-CD1 4.22Å; L442-Y507 HydrophobicContact CD1-CD1 3.8Å; L442-Y507 HydrophobicContact CD1-CG 3.89Å; L442-Y507 HydrophobicContact CG-CD1 4.22Å; L442-V532 HydrophobicContact CD1-CB 4.25Å; L442-V532 HydrophobicContact CD1-CG1 3.5Å; L442-V532 VanDerWaalsContact CD1-CG1 3.5Å; L442-V532 HydrophobicContact CD2-CG1 4.06Å; L442-V532 HydrophobicContact CG-CG1 4.44Å
443	G	80.9	Confident	77	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-66.9	-43.2	174.6	0	0	0	0	0	113.7	G172 I173 F439 A440 F441 S445 I446	G172-G443 CarbonylContact O-C 3.59Å; I173-G443 WeakPolarHBondContact CA-O 3.5Å; F439-G443 PolarHBondContact O-N 2.8Å; F439-G443 VanDerWaalsContact O-N 3.13Å; A440-G443 PolarHBondContact O-N 3.48Å; F441-G443 VanDerWaalsContact C-N 3.33Å; F441-G443 PolarHBondContact O-N 3.27Å; G443-S445 VanDerWaalsContact C-N 3.26Å; G443-S445 PolarHBondContact O-N 3.48Å; G443-I446 WeakPolarHBondContact O-CG1 3.38Å; G443-I446 PolarHBondContact O-N 3.48Å
444	L	77.9	Confident	77	Confident	16 Å²	16	36.7 Å²	36.7	8%	0.084	19%	0.188	C	C	.	.	H	α-helix	trans	-59.8	-37.7	176.5	173.7	59.6	0	0	0	112.1	G172 M175 G176 I179 A440 F441 I446 F447 S448	G172-L444 WeakPolarHBondContact O-CA 3.34Å; G172-L444 PolarHBondContact O-N 3.14Å; M175-L444 HydrophobicContact CE-CD2 4.39Å; G176-L444 VanDerWaalsContact CA-CD1 3.5Å; I179-L444 HydrophobicContact CD1-CD1 3.92Å; A440-L444 PolarHBondContact O-N 2.87Å; F441-L444 HydrophobicContact CD1-CD2 4.4Å; F441-L444 PolarHBondContact O-N 3.47Å; L444-I446 PolarHBondContact O-N 3.5Å; L444-I446 VanDerWaalsContact O-N 3.11Å; L444-F447 PolarHBondContact O-N 3.34Å; L444-F447 VanDerWaalsContact O-N 3.13Å; L444-S448 PolarHBondContact O-N 3.42Å
445	S	77.8	Confident	76.9	Confident	5 Å²	5	41.8 Å²	41.8	4%	0.035	21%	0.213	C	C	.	.	H	α-helix	trans	-62.7	-20	-175.3	-62.2	0	0	0	0	114.2	F441 G443 F447 F449 H451 Y507	F441-S445 WeakPolarHBondContact O-CB 3.45Å; F441-S445 PolarHBondContact O-N 3.39Å; F441-S445 PolarHBondContact O-OG 2.93Å; G443-S445 VanDerWaalsContact C-N 3.26Å; G443-S445 PolarHBondContact O-N 3.48Å; S445-F447 PolarHBondContact O-N 3.02Å; S445-F449 PolarHBondContact O-N 2.9Å; S445-H451 PolarHBondContact O-NE2 2.89Å; S445-Y507 WeakPolarHBondContact CB-OH 3.46Å; S445-Y507 PolarHBondContact OG-OH 2.89Å
446	I	80.7	Confident	77.3	Confident	38 Å²	38	42.5 Å²	42.5	20%	0.195	22%	0.221	C	C	.	.	H	α-helix	trans	-67.8	-17.6	177.7	-51.1	-158.6	0	0	0	112.6	I173 G443 L444 H451 I529 L533	I173-I446 HydrophobicContact CD1-CD1 3.87Å; I173-I446 HydrophobicContact CG1-CD1 3.92Å; I173-I446 HydrophobicContact CG1-CG1 4.41Å; G443-I446 WeakPolarHBondContact O-CG1 3.38Å; G443-I446 PolarHBondContact O-N 3.48Å; L444-I446 PolarHBondContact O-N 3.5Å; L444-I446 VanDerWaalsContact O-N 3.11Å; I446-H451 PolarHBondContact O-NE2 2.85Å; I446-H451 VanDerWaalsContact O-NE2 3.16Å; I446-I529 HydrophobicContact CD1-CG2 3.82Å; I446-I529 HydrophobicContact CG1-CG2 3.72Å; I446-L533 HydrophobicContact CD1-CD1 4.49Å; I446-L533 HydrophobicContact CD1-CD2 3.84Å
447	F	74.6	Confident	77.6	Confident	69 Å²	69	42.3 Å²	42.3	30%	0.303	22%	0.219	S	C	.	.	H	α-helix	trans	-112.5	-28.8	179.1	-74	-74.2	0	0	0	114.2	I173 G176 K180 L444 S445	I173-F447 HydrophobicContact CG2-CE2 3.82Å; I173-F447 WeakPolarHBondContact O-CD2 3.46Å; I173-F447 WeakPolarHBondContact O-CE2 3.39Å; G176-F447 VanDerWaalsContact C-CB 3.49Å; G176-F447 WeakPolarHBondContact O-CB 3.42Å; K180-F447 HydrophobicContact CD-CB 4.2Å; K180-F447 HydrophobicContact CD-CD1 3.88Å; K180-F447 PolarHBondContact NZ-O 3.47Å; L444-F447 PolarHBondContact O-N 3.34Å; L444-F447 VanDerWaalsContact O-N 3.13Å; S445-F447 PolarHBondContact O-N 3.02Å
448	S	67.1	Low	78.1	Confident	33 Å²	33	42 Å²	42	23%	0.231	22%	0.217	C	C	.	.	H	α-helix	trans	-81.8	-36.2	-177.7	-165.8	0	0	0	0	113.5	E194 L444	E194-S448 VanDerWaalsContact CB-OG 3.27Å; E194-S448 WeakPolarHBondContact CB-OG 3.45Å; E194-S448 VanDerWaalsContact OE2-CB 3.23Å; E194-S448 WeakPolarHBondContact OE2-CB 3.26Å; E194-S448 PolarHBondContact OE2-OG 3.14Å; L444-S448 PolarHBondContact O-N 3.42Å
449	F	66.8	Low	78.5	Confident	45 Å²	45	46 Å²	46	20%	0.197	24%	0.237	C	C	.	.	S	Bend	trans	-75.7	141.4	-177.1	-83.7	-92.3	0	0	0	113	S445 H451 Y507 L511	S445-F449 PolarHBondContact O-N 2.9Å; F449-H451 PolarHBondContact O-CD2 3.37Å; F449-H451 PolarHBondContact O-N 3.49Å; F449-Y507 WeakPolarHBondContact CE2-OH 3.38Å; F449-L511 HydrophobicContact CE1-CD2 3.73Å; F449-L511 HydrophobicContact CE2-CD2 4.35Å; F449-L511 HydrophobicContact CZ-CD1 4.22Å; F449-L511 HydrophobicContact CZ-CD2 3.55Å
450	P	68.4	Low	79.1	Confident	74 Å²	74	50.4 Å²	50.4	48%	0.481	25%	0.253	S	S	.	.			trans	-70.5	111.3	165.9	28.9	-32.6	0	0	0	109.5	Q522	P450-Q522 HydrophobicContact CG-CG 4.34Å
451	H	71.7	Confident	79.6	Confident	36 Å²	36	49.9 Å²	49.9	17%	0.167	25%	0.249	C	C	.	.			trans	-99.1	116.7	-172.9	-68.6	-52.7	0	0	0	113	S445 I446 F449 F453 T526	S445-H451 PolarHBondContact O-NE2 2.89Å; I446-H451 PolarHBondContact O-NE2 2.85Å; I446-H451 VanDerWaalsContact O-NE2 3.16Å; F449-H451 PolarHBondContact O-CD2 3.37Å; F449-H451 PolarHBondContact O-N 3.49Å; H451-F453 HydrophobicContact CB-CD2 3.84Å; H451-F453 HydrophobicContact CB-CE1 4.15Å; H451-F453 HydrophobicContact CB-CE2 3.29Å; H451-F453 HydrophobicContact CB-CG 4.48Å; H451-F453 HydrophobicContact CB-CZ 3.47Å; H451-F453 VanDerWaalsContact CB-CZ 3.47Å; H451-F453 AromaticContact CD2-CZ 3.97Å; H451-F453 AromaticContact CG-CZ 3.84Å; H451-T526 HydrophobicContact CB-CG2 3.87Å; H451-T526 PolarHBondContact ND1-OG1 3.08Å
452	N	71.8	Confident	80.3	Confident	69 Å²	69	48.3 Å²	48.3	37%	0.369	24%	0.243	S	C	.	.			trans	-92.9	98.9	170.9	-60.4	-24.4	0	0	0	108.6	E454 Q522	N452-E454 PolarHBondContact O-N 3.31Å; N452-Q522 PolarHBondContact ND2-OE1 3.42Å
453	F	69.3	Low	80.9	Confident	127 Å²	127	51.6 Å²	51.6	56%	0.557	26%	0.263	S	S	*	.			trans	-87.9	79.5	-171.3	-71.2	-74.6	0	0	0	113.6	H451 I455 T526 I530	H451-F453 HydrophobicContact CB-CD2 3.84Å; H451-F453 HydrophobicContact CB-CE1 4.15Å; H451-F453 HydrophobicContact CB-CE2 3.29Å; H451-F453 HydrophobicContact CB-CG 4.48Å; H451-F453 HydrophobicContact CB-CZ 3.47Å; H451-F453 VanDerWaalsContact CB-CZ 3.47Å; H451-F453 AromaticContact CD2-CZ 3.97Å; H451-F453 AromaticContact CG-CZ 3.84Å; F453-I455 PolarHBondContact O-N 3.07Å; F453-I455 VanDerWaalsContact O-N 3.08Å; F453-T526 HydrophobicContact CD1-CG2 3.79Å; F453-T526 HydrophobicContact CE1-CG2 3.71Å; F453-T526 HydrophobicContact CZ-CG2 4.39Å; F453-I530 HydrophobicContact CD1-CD1 4Å; F453-I530 HydrophobicContact CE1-CD1 3.95Å
454	E	80.5	Confident	81.5	Confident	96 Å²	96	52.3 Å²	52.3	45%	0.449	27%	0.267	S	S	.	.			trans	-76.9	89	168.5	-75.1	-61.2	159.9	0	0	111.5	N452 S456 F457 V458 L523	N452-E454 PolarHBondContact O-N 3.31Å; E454-S456 VanDerWaalsContact C-N 3.26Å; E454-S456 PolarHBondContact O-N 3.13Å; E454-F457 HydrophobicContact CB-CB 3.81Å; E454-F457 WeakPolarHBondContact O-CB 3.24Å; E454-F457 PolarHBondContact O-N 2.76Å; E454-V458 WeakPolarHBondContact O-CG2 3.36Å; E454-V458 PolarHBondContact O-N 2.65Å; E454-L523 HydrophobicContact CB-CD1 3.8Å; E454-L523 HydrophobicContact CG-CD1 4.04Å
455	I	85.4	Confident	82.2	Confident	120 Å²	120	51.8 Å²	51.8	62%	0.615	26%	0.264	S	S	*	.	H	α-helix	trans	-56.8	-37.9	-174.3	-61.3	173.3	0	0	0	112	F453 V458 I459	F453-I455 PolarHBondContact O-N 3.07Å; F453-I455 VanDerWaalsContact O-N 3.08Å; I455-V458 PolarHBondContact O-N 2.87Å; I455-I459 HydrophobicContact CG2-CD1 3.73Å; I455-I459 HydrophobicContact CG2-CG1 4.41Å; I455-I459 WeakPolarHBondContact O-CG1 3.41Å; I455-I459 PolarHBondContact O-N 3.46Å; I455-I459 VanDerWaalsContact O-N 3.08Å
456	S	87.3	Confident	82.9	Confident	45 Å²	45	54.1 Å²	54.1	32%	0.315	28%	0.276	S	S	.	.	H	α-helix	trans	-61.2	-49	175.9	-172.3	0	0	0	0	111.5	V256 E454 V458 I459 W460	V256-S456 PolarHBondContact O-OG 2.9Å; E454-S456 VanDerWaalsContact C-N 3.26Å; E454-S456 PolarHBondContact O-N 3.13Å; S456-V458 PolarHBondContact O-N 2.99Å; S456-I459 PolarHBondContact O-N 2.91Å; S456-W460 VanDerWaalsContact O-CD1 3.26Å; S456-W460 PolarHBondContact O-N 3.47Å
457	F	87.6	Confident	83.5	Confident	1 Å²	1	56.1 Å²	56.1	0%	0.004	29%	0.287	C	S	.	.	H	α-helix	trans	-60	-46.1	179.4	-174.1	-89.6	0	0	0	111.1	I248 I257 M260 E454 C461 L523 T527	I248-F457 HydrophobicContact CG2-CE2 3.94Å; I248-F457 HydrophobicContact CG2-CZ 4.37Å; I257-F457 HydrophobicContact CB-CB 4.3Å; I257-F457 HydrophobicContact CB-CD2 3.99Å; I257-F457 HydrophobicContact CD1-CD2 3.82Å; I257-F457 HydrophobicContact CD1-CE2 4.12Å; I257-F457 HydrophobicContact CG1-CD2 4.06Å; M260-F457 HydrophobicContact CG-CE2 4.16Å; M260-F457 HydrophobicContact SD-CE2 3.78Å; M260-F457 HydrophobicContact SD-CZ 3.69Å; E454-F457 HydrophobicContact CB-CB 3.81Å; E454-F457 WeakPolarHBondContact O-CB 3.24Å; E454-F457 PolarHBondContact O-N 2.76Å; F457-C461 VanDerWaalsContact O-CB 3.29Å; F457-C461 WeakPolarHBondContact O-CB 3.31Å; F457-C461 PolarHBondContact O-N 3.27Å; F457-C461 PolarHBondContact O-SG 3.02Å; F457-L523 HydrophobicContact CD1-CD1 4.06Å; F457-L523 HydrophobicContact CD1-CG 4.33Å; F457-L523 HydrophobicContact CE1-CD1 4.5Å; F457-L523 HydrophobicContact CE1-CG 4.31Å; F457-L523 HydrophobicContact CG-CD1 4.42Å; F457-T527 HydrophobicContact CD1-CG2 3.86Å; F457-T527 WeakPolarHBondContact CD1-OG1 3.26Å; F457-T527 HydrophobicContact CE1-CG2 3.78Å; F457-T527 WeakPolarHBondContact CE1-OG1 3.16Å
458	V	90.1	Very high	84.3	Confident	14 Å²	14	52.9 Å²	52.9	9%	0.085	27%	0.273	C	S	.	.	H	α-helix	trans	-61.4	-47.7	179.4	176.4	0	0	0	0	112.2	E454 I455 S456 C461 I462 T527 I530	E454-V458 WeakPolarHBondContact O-CG2 3.36Å; E454-V458 PolarHBondContact O-N 2.65Å; I455-V458 PolarHBondContact O-N 2.87Å; S456-V458 PolarHBondContact O-N 2.99Å; V458-C461 PolarHBondContact O-N 2.88Å; V458-I462 HydrophobicContact CG1-CD1 4.11Å; V458-I462 WeakPolarHBondContact O-CG1 3.44Å; V458-I462 PolarHBondContact O-N 3.38Å; V458-T527 HydrophobicContact CG2-CG2 4.18Å; V458-I530 HydrophobicContact CG1-CB 4.15Å; V458-I530 HydrophobicContact CG1-CD1 4.04Å; V458-I530 HydrophobicContact CG1-CG2 3.66Å; V458-I530 HydrophobicContact CG2-CD1 3.82Å
459	I	91.4	Very high	85.5	Confident	96 Å²	96	51.6 Å²	51.6	49%	0.492	26%	0.263	S	S	.	.	H	α-helix	trans	-63.9	-46.7	-178.8	-68.8	169.8	0	0	0	110.8	I455 S456 C461 I462 V463	I455-I459 HydrophobicContact CG2-CD1 3.73Å; I455-I459 HydrophobicContact CG2-CG1 4.41Å; I455-I459 WeakPolarHBondContact O-CG1 3.41Å; I455-I459 PolarHBondContact O-N 3.46Å; I455-I459 VanDerWaalsContact O-N 3.08Å; S456-I459 PolarHBondContact O-N 2.91Å; I459-C461 PolarHBondContact O-N 3.46Å; I459-I462 PolarHBondContact O-N 2.99Å; I459-V463 WeakPolarHBondContact O-CG2 3.34Å; I459-V463 PolarHBondContact O-N 3.47Å
460	W	92.1	Very high	86.6	Confident	103 Å²	103	50.4 Å²	50.4	39%	0.39	26%	0.261	S	S	.	.	H	α-helix	trans	-64.6	-37.9	177.8	-80.1	114.3	0	0	0	112.7	L251 I257 S456 V463 L464	L251-W460 HydrophobicContact CD2-CB 3.78Å; L251-W460 HydrophobicContact CD2-CD2 3.37Å; L251-W460 HydrophobicContact CD2-CE3 3.62Å; L251-W460 HydrophobicContact CD2-CG 3.45Å; L251-W460 VanDerWaalsContact CD2-CG 3.45Å; L251-W460 HydrophobicContact CD2-CZ3 4.31Å; I257-W460 HydrophobicContact CG2-CB 4.1Å; I257-W460 HydrophobicContact CG2-CG 4.09Å; S456-W460 VanDerWaalsContact O-CD1 3.26Å; S456-W460 PolarHBondContact O-N 3.47Å; W460-V463 PolarHBondContact O-N 3.02Å; W460-L464 WeakPolarHBondContact O-CB 3.45Å; W460-L464 VanDerWaalsContact O-CG 3.29Å; W460-L464 WeakPolarHBondContact O-CG 3.21Å; W460-L464 PolarHBondContact O-N 3.17Å
461	C	91.7	Very high	87.8	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-63.6	-39.7	174	-72.8	0	0	0	0	112.4	I248 F268 F457 V458 I459 L464 V465 T527 I531	I248-C461 VanDerWaalsContact CD1-SG 3.55Å; F268-C461 HydrophobicContact CE1-CB 4.43Å; F457-C461 VanDerWaalsContact O-CB 3.29Å; F457-C461 WeakPolarHBondContact O-CB 3.31Å; F457-C461 PolarHBondContact O-N 3.27Å; F457-C461 PolarHBondContact O-SG 3.02Å; V458-C461 PolarHBondContact O-N 2.88Å; I459-C461 PolarHBondContact O-N 3.46Å; C461-L464 PolarHBondContact O-N 3.16Å; C461-V465 VanDerWaalsContact O-CB 3.31Å; C461-V465 WeakPolarHBondContact O-CB 3.23Å; C461-V465 WeakPolarHBondContact O-CG2 3.49Å; C461-V465 PolarHBondContact O-N 2.76Å; C461-T527 HydrophobicContact CB-CG2 4.05Å; C461-I531 HydrophobicContact CB-CD1 3.85Å
462	I	92.3	Very high	88.7	Confident	28 Å²	28	48.7 Å²	48.7	14%	0.144	25%	0.249	C	C	.	.	H	α-helix	trans	-61.7	-45.7	173.7	-68.9	167.4	0	0	0	110.9	V458 I459 V465 L466 I531 F534	V458-I462 HydrophobicContact CG1-CD1 4.11Å; V458-I462 WeakPolarHBondContact O-CG1 3.44Å; V458-I462 PolarHBondContact O-N 3.38Å; I459-I462 PolarHBondContact O-N 2.99Å; I462-V465 PolarHBondContact O-N 3.17Å; I462-L466 HydrophobicContact CG2-CD1 4.17Å; I462-L466 WeakPolarHBondContact O-CG 3.42Å; I462-L466 PolarHBondContact O-N 3.36Å; I462-I531 HydrophobicContact CG1-CG1 3.87Å; I462-F534 HydrophobicContact CD1-CD1 4.37Å; I462-F534 HydrophobicContact CD1-CG 4.28Å; I462-F534 HydrophobicContact CG1-CD1 4.47Å; I462-F534 HydrophobicContact CG2-CD1 3.95Å; I462-F534 HydrophobicContact CG2-CE1 3.62Å; I462-F534 HydrophobicContact CG2-CZ 4.2Å
463	V	93.5	Very high	89.6	Confident	68 Å²	68	45.5 Å²	45.5	41%	0.412	23%	0.231	S	C	.	.	H	α-helix	trans	-61.7	-46.3	177.4	172.5	0	0	0	0	111.3	I459 W460 V465 L466 L467	I459-V463 WeakPolarHBondContact O-CG2 3.34Å; I459-V463 PolarHBondContact O-N 3.47Å; W460-V463 PolarHBondContact O-N 3.02Å; V463-V465 PolarHBondContact O-N 3.09Å; V463-L466 PolarHBondContact O-N 3.19Å; V463-L467 VanDerWaalsContact O-CB 3.25Å; V463-L467 WeakPolarHBondContact O-CB 3.28Å; V463-L467 PolarHBondContact O-N 3.38Å
464	L	93.5	Very high	90.7	Very high	16 Å²	16	43.1 Å²	43.1	8%	0.084	22%	0.221	C	C	.	.	H	α-helix	trans	-64.5	-37.5	178.1	-73.1	171.3	0	0	0	112.4	V244 I248 W460 C461 L467 G468	V244-L464 HydrophobicContact CG2-CB 4.41Å; I248-L464 HydrophobicContact CG1-CD1 3.91Å; W460-L464 WeakPolarHBondContact O-CB 3.45Å; W460-L464 VanDerWaalsContact O-CG 3.29Å; W460-L464 WeakPolarHBondContact O-CG 3.21Å; W460-L464 PolarHBondContact O-N 3.17Å; C461-L464 PolarHBondContact O-N 3.16Å; L464-L467 PolarHBondContact O-N 3.4Å; L464-G468 PolarHBondContact O-N 3.25Å
465	V	92.5	Very high	91.2	Very high	5 Å²	5	41.9 Å²	41.9	3%	0.03	22%	0.221	C	C	.	.	H	α-helix	trans	-66	-42	176.8	163.8	0	0	0	0	111.7	V244 I272 C461 I462 V463 R469 R502 I531	V244-V465 HydrophobicContact CG1-CG2 4.32Å; V244-V465 HydrophobicContact CG2-CG2 4.07Å; I272-V465 HydrophobicContact CG1-CG2 3.92Å; I272-V465 HydrophobicContact CG2-CG2 3.97Å; C461-V465 VanDerWaalsContact O-CB 3.31Å; C461-V465 WeakPolarHBondContact O-CB 3.23Å; C461-V465 WeakPolarHBondContact O-CG2 3.49Å; C461-V465 PolarHBondContact O-N 2.76Å; I462-V465 PolarHBondContact O-N 3.17Å; V463-V465 PolarHBondContact O-N 3.09Å; V465-R469 WeakPolarHBondContact O-CB 3.27Å; V465-R469 PolarHBondContact O-N 2.88Å; V465-R469 VanDerWaalsContact O-N 3.13Å; V465-R502 HydrophobicContact CG1-CG 4.48Å; V465-I531 HydrophobicContact CG1-CG2 4.37Å; V465-I531 HydrophobicContact CG2-CD1 4.49Å
466	L	92.4	Very high	91.3	Very high	53 Å²	53	36.7 Å²	36.7	28%	0.277	20%	0.195	S	C	.	.	H	α-helix	trans	-68.9	-38.1	175.1	-69.7	172.5	0	0	0	112.3	I462 V463 R469 A470 W497 L539	I462-L466 HydrophobicContact CG2-CD1 4.17Å; I462-L466 WeakPolarHBondContact O-CG 3.42Å; I462-L466 PolarHBondContact O-N 3.36Å; V463-L466 PolarHBondContact O-N 3.19Å; L466-R469 PolarHBondContact O-N 3.32Å; L466-A470 PolarHBondContact O-N 3.45Å; L466-W497 PolarHBondContact O-NE1 3.45Å; L466-L539 HydrophobicContact CD2-CD1 4.11Å
467	L	93.6	Very high	91.4	Very high	81 Å²	81	34.6 Å²	34.6	42%	0.424	18%	0.18	S	C	.	.	H	α-helix	trans	-70.6	-43.1	178.1	-177.5	61.5	0	0	0	112.1	V463 L464 R469 A470 I471	V463-L467 VanDerWaalsContact O-CB 3.25Å; V463-L467 WeakPolarHBondContact O-CB 3.28Å; V463-L467 PolarHBondContact O-N 3.38Å; L464-L467 PolarHBondContact O-N 3.4Å; L467-R469 VanDerWaalsContact C-N 3.29Å; L467-R469 PolarHBondContact O-N 3.18Å; L467-A470 WeakPolarHBondContact O-CB 3.3Å; L467-A470 PolarHBondContact O-N 3.23Å; L467-I471 HydrophobicContact CD1-CD1 3.79Å; L467-I471 HydrophobicContact CD1-CG1 4.23Å; L467-I471 HydrophobicContact CG-CD1 3.82Å; L467-I471 WeakPolarHBondContact O-CG1 3.3Å; L467-I471 PolarHBondContact O-N 2.97Å
468	G	91.8	Very high	91.3	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-60.2	-38.7	173	0	0	0	0	0	112	L464 N472	L464-G468 PolarHBondContact O-N 3.25Å; G468-N472 WeakPolarHBondContact O-CB 3.36Å; G468-N472 PolarHBondContact O-N 3.43Å
469	R	91.3	Very high	91.2	Very high	6 Å²	6	46 Å²	46	2%	0.023	23%	0.232	C	C	.	.	H	α-helix	trans	-66.8	-32.7	172	-169.1	66.3	-176.3	170	5.9	112.8	E300 V465 L466 L467 N472 I473 M496 W497	E300-R469 VanDerWaalsContact CD-NH1 3.29Å; E300-R469 IonicContact OE1-CZ 3.65Å; E300-R469 IonicContact OE1-NH1 3.21Å; E300-R469 PolarHBondContact OE1-NH1 2.79Å; E300-R469 IonicContact OE1-NH2 3.91Å; E300-R469 IonicContact OE2-CZ 3.02Å; E300-R469 IonicContact OE2-NH1 2.99Å; E300-R469 PolarHBondContact OE2-NH1 3.25Å; E300-R469 VanDerWaalsContact OE2-NH1 3.12Å; E300-R469 IonicContact OE2-NH2 3.96Å; E300-R469 PolarHBondContact OE2-NH2 3.41Å; V465-R469 WeakPolarHBondContact O-CB 3.27Å; V465-R469 PolarHBondContact O-N 2.88Å; V465-R469 VanDerWaalsContact O-N 3.13Å; L466-R469 PolarHBondContact O-N 3.32Å; L467-R469 VanDerWaalsContact C-N 3.29Å; L467-R469 PolarHBondContact O-N 3.18Å; R469-N472 WeakPolarHBondContact CA-OD1 3.49Å; R469-N472 PolarHBondContact O-OD1 3.48Å; R469-I473 WeakPolarHBondContact O-CB 3.35Å; R469-I473 WeakPolarHBondContact O-CG1 3.31Å; R469-I473 PolarHBondContact O-N 3.27Å; R469-M496 PolarHBondContact NE-O 2.76Å; R469-M496 PolarHBondContact NH2-O 3.29Å; R469-W497 VanDerWaalsContact C-CD1 3.45Å; R469-W497 WeakPolarHBondContact CG-O 3.45Å
470	A	91.8	Very high	90.9	Very high	20 Å²	20	42.2 Å²	42.2	17%	0.165	21%	0.213	C	C	.	.	H	α-helix	trans	-70.8	-47.8	175.4	0	0	0	0	0	111.1	L466 L467 N472 I473 F474 W497	L466-A470 PolarHBondContact O-N 3.45Å; L467-A470 WeakPolarHBondContact O-CB 3.3Å; L467-A470 PolarHBondContact O-N 3.23Å; A470-N472 VanDerWaalsContact C-N 3.3Å; A470-N472 PolarHBondContact O-N 2.9Å; A470-I473 PolarHBondContact O-N 3.2Å; A470-F474 HydrophobicContact CB-CD2 4.15Å; A470-F474 HydrophobicContact CB-CE2 4.17Å; A470-F474 VanDerWaalsContact O-CD2 3.25Å; A470-F474 WeakPolarHBondContact O-CD2 3.44Å; A470-F474 PolarHBondContact O-N 2.91Å; A470-F474 VanDerWaalsContact O-N 3.07Å; A470-W497 VanDerWaalsContact CA-CD1 3.47Å
471	I	92.4	Very high	90.7	Very high	72 Å²	72	38.7 Å²	38.7	37%	0.369	20%	0.202	S	C	.	.	H	α-helix	trans	-73.8	-19.8	-176.7	-61.3	169.5	0	0	0	111.9	I239 I243 L467 P475	I239-I471 HydrophobicContact CG2-CG2 4.27Å; I243-I471 HydrophobicContact CD1-CB 3.57Å; I243-I471 HydrophobicContact CD1-CD1 4Å; I243-I471 HydrophobicContact CD1-CG1 4.38Å; I243-I471 HydrophobicContact CD1-CG2 3.4Å; L467-I471 HydrophobicContact CD1-CD1 3.79Å; L467-I471 HydrophobicContact CD1-CG1 4.23Å; L467-I471 HydrophobicContact CG-CD1 3.82Å; L467-I471 WeakPolarHBondContact O-CG1 3.3Å; L467-I471 PolarHBondContact O-N 2.97Å; I471-P475 WeakPolarHBondContact O-CD 3.46Å; I471-P475 WeakPolarHBondContact O-CG 3.47Å
472	N	90.9	Very high	90.2	Very high	3 Å²	3	46.8 Å²	46.8	2%	0.016	24%	0.237	C	C	.	.	H	α-helix	trans	-82.7	-46.5	168.2	83.2	-5.1	0	0	0	113.2	G236 I239 G468 R469 A470 L476	G236-N472 WeakPolarHBondContact O-CB 3.17Å; G236-N472 PolarHBondContact O-ND2 3.29Å; I239-N472 HydrophobicContact CB-CB 4.23Å; I239-N472 HydrophobicContact CG2-CB 3.94Å; G468-N472 WeakPolarHBondContact O-CB 3.36Å; G468-N472 PolarHBondContact O-N 3.43Å; R469-N472 WeakPolarHBondContact CA-OD1 3.49Å; R469-N472 PolarHBondContact O-OD1 3.48Å; A470-N472 VanDerWaalsContact C-N 3.3Å; A470-N472 PolarHBondContact O-N 2.9Å; N472-L476 VanDerWaalsContact O-CB 3.31Å; N472-L476 WeakPolarHBondContact O-CB 3.24Å; N472-L476 WeakPolarHBondContact O-CD1 3.27Å; N472-L476 VanDerWaalsContact O-CG 3.26Å; N472-L476 WeakPolarHBondContact O-CG 3.33Å
473	I	90.4	Very high	89.5	Confident	1 Å²	1	53 Å²	53	1%	0.005	26%	0.264	C	S	.	.	H	α-helix	trans	-71	-53.3	-176.1	-67.5	-51.5	0	0	0	113	F232 R469 A470 S477 M493 M496	F232-I473 HydrophobicContact CD1-CD1 4.05Å; F232-I473 HydrophobicContact CE1-CD1 4.18Å; R469-I473 WeakPolarHBondContact O-CB 3.35Å; R469-I473 WeakPolarHBondContact O-CG1 3.31Å; R469-I473 PolarHBondContact O-N 3.27Å; A470-I473 PolarHBondContact O-N 3.2Å; I473-S477 WeakPolarHBondContact O-CB 3.41Å; I473-S477 PolarHBondContact O-N 3.17Å; I473-S477 PolarHBondContact O-OG 3.26Å; I473-M493 HydrophobicContact CG2-CB 4.33Å; I473-M496 HydrophobicContact CD1-CB 4.43Å; I473-M496 HydrophobicContact CG1-CB 4.5Å; I473-M496 HydrophobicContact CG2-CB 4.06Å; I473-M496 HydrophobicContact CG2-CE 4.05Å
474	F	91.9	Very high	88.6	Confident	77 Å²	77	51 Å²	51	34%	0.338	25%	0.249	S	C	.	.	H	α-helix	trans	-66	-47.7	-169.8	-65	-68.6	0	0	0	113.3	A470 F478 M493 F494 W497	A470-F474 HydrophobicContact CB-CD2 4.15Å; A470-F474 HydrophobicContact CB-CE2 4.17Å; A470-F474 VanDerWaalsContact O-CD2 3.25Å; A470-F474 WeakPolarHBondContact O-CD2 3.44Å; A470-F474 PolarHBondContact O-N 2.91Å; A470-F474 VanDerWaalsContact O-N 3.07Å; F474-F478 WeakPolarHBondContact O-CB 3.37Å; F474-F478 PolarHBondContact O-N 3.03Å; F474-M493 HydrophobicContact CD1-CB 3.77Å; F474-M493 HydrophobicContact CD1-SD 4.13Å; F474-M493 HydrophobicContact CE1-CB 3.7Å; F474-F494 HydrophobicContact CZ-CD2 4.48Å; F474-W497 HydrophobicContact CE2-CB 4.36Å; F474-W497 HydrophobicContact CE2-CG 4.21Å; F474-W497 HydrophobicContact CZ-CB 4.24Å; F474-W497 HydrophobicContact CZ-CG 4.44Å
475	P	91.1	Very high	87.2	Confident	71 Å²	71	58.2 Å²	58.2	46%	0.461	29%	0.288	S	S	.	.	H	α-helix	trans	-68.7	-40.1	180	-21.6	36.5	0	0	0	113.5	I471 F478 L479	I471-P475 WeakPolarHBondContact O-CD 3.46Å; I471-P475 WeakPolarHBondContact O-CG 3.47Å; P475-F478 PolarHBondContact O-N 3.46Å; P475-L479 WeakPolarHBondContact O-CB 3.38Å; P475-L479 PolarHBondContact O-N 3.38Å
476	L	88.4	Confident	86.2	Confident	11 Å²	11	62.8 Å²	62.8	6%	0.058	31%	0.308	C	S	.	.	H	α-helix	trans	-68.9	-37.6	177.2	-65.4	179.3	0	0	0	111.7	L231 F232 I235 G236 I239 N472 L479 L480	L231-L476 HydrophobicContact CD2-CB 4.47Å; L231-L476 HydrophobicContact CD2-CD2 4.07Å; L231-L476 HydrophobicContact CG-CD2 4.2Å; F232-L476 HydrophobicContact CD1-CB 3.93Å; F232-L476 HydrophobicContact CD1-CD1 4.11Å; F232-L476 HydrophobicContact CE1-CB 3.71Å; I235-L476 HydrophobicContact CG2-CD2 4.2Å; G236-L476 VanDerWaalsContact CA-CD1 3.41Å; I239-L476 HydrophobicContact CD1-CD1 4.47Å; I239-L476 HydrophobicContact CD1-CD2 4.42Å; N472-L476 VanDerWaalsContact O-CB 3.31Å; N472-L476 WeakPolarHBondContact O-CB 3.24Å; N472-L476 WeakPolarHBondContact O-CD1 3.27Å; N472-L476 VanDerWaalsContact O-CG 3.26Å; N472-L476 WeakPolarHBondContact O-CG 3.33Å; L476-L479 PolarHBondContact O-N 3.36Å; L476-L480 WeakPolarHBondContact O-CB 3.28Å; L476-L480 WeakPolarHBondContact O-CG 3.31Å; L476-L480 PolarHBondContact O-N 3.38Å
477	S	88.3	Confident	85.5	Confident	0 Å²	0	66.4 Å²	66.4	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-65.2	-38.6	174	-57.7	0	0	0	0	112	F232 I473 N481 M493 M496	F232-S477 WeakPolarHBondContact CZ-OG 3.35Å; I473-S477 WeakPolarHBondContact O-CB 3.41Å; I473-S477 PolarHBondContact O-N 3.17Å; I473-S477 PolarHBondContact O-OG 3.26Å; S477-N481 WeakPolarHBondContact O-CB 3.44Å; S477-N481 VanDerWaalsContact O-CG 3.23Å; S477-N481 PolarHBondContact O-N 2.87Å; S477-M493 VanDerWaalsContact CB-SD 3.55Å; S477-M496 WeakPolarHBondContact OG-CE 3.29Å
478	F	87.1	Confident	84.9	Confident	164 Å²	164	62.7 Å²	62.7	72%	0.719	30%	0.303	S	S	*	.	H	α-helix	trans	-64.1	-43.7	174.1	-177.1	-95.6	0	0	0	111.9	F474 P475 N481	F474-F478 WeakPolarHBondContact O-CB 3.37Å; F474-F478 PolarHBondContact O-N 3.03Å; P475-F478 PolarHBondContact O-N 3.46Å; F478-N481 PolarHBondContact O-N 2.81Å
479	L	87.5	Confident	84.5	Confident	90 Å²	90	65.6 Å²	65.6	47%	0.471	32%	0.32	S	S	.	.	H	α-helix	trans	-63.5	-45.8	176	-177.3	62.9	0	0	0	112	P475 L476 N481 F482 F483	P475-L479 WeakPolarHBondContact O-CB 3.38Å; P475-L479 PolarHBondContact O-N 3.38Å; L476-L479 PolarHBondContact O-N 3.36Å; L479-N481 VanDerWaalsContact C-N 3.3Å; L479-N481 PolarHBondContact O-N 3.2Å; L479-F482 WeakPolarHBondContact O-CB 3.41Å; L479-F482 PolarHBondContact O-N 3.08Å; L479-F483 HydrophobicContact CD1-CE2 4.24Å; L479-F483 WeakPolarHBondContact O-CD2 3.04Å
480	L	85.3	Confident	84.1	Confident	18 Å²	18	70 Å²	70	9%	0.094	35%	0.35	C	S	.	.	H	α-helix	trans	-62.9	-34.8	177.5	-76.8	168.7	0	0	0	112.7	L231 F232 L476 F482 F483 R484	L231-L480 HydrophobicContact CD2-CD1 3.94Å; L231-L480 HydrophobicContact CD2-CD2 3.72Å; L231-L480 HydrophobicContact CD2-CG 3.64Å; F232-L480 HydrophobicContact CD2-CD1 4.09Å; F232-L480 HydrophobicContact CE1-CD1 4.22Å; F232-L480 HydrophobicContact CE2-CD1 3.43Å; F232-L480 VanDerWaalsContact CE2-CD1 3.43Å; F232-L480 HydrophobicContact CZ-CD1 3.51Å; L476-L480 WeakPolarHBondContact O-CB 3.28Å; L476-L480 WeakPolarHBondContact O-CG 3.31Å; L476-L480 PolarHBondContact O-N 3.38Å; L480-F482 PolarHBondContact O-N 2.93Å; L480-F482 VanDerWaalsContact O-N 3.11Å; L480-F483 PolarHBondContact O-N 3.41Å; L480-R484 WeakPolarHBondContact O-CB 3.28Å; L480-R484 PolarHBondContact O-N 3.02Å
481	N	86.4	Confident	83.6	Confident	28 Å²	28	73 Å²	73	15%	0.15	36%	0.359	C	S	.	.	H	α-helix	trans	-64.9	-9.8	176.9	-82.5	-7.3	0	0	0	114.7	S477 F478 L479 K487 I488 M493	S477-N481 WeakPolarHBondContact O-CB 3.44Å; S477-N481 VanDerWaalsContact O-CG 3.23Å; S477-N481 PolarHBondContact O-N 2.87Å; F478-N481 PolarHBondContact O-N 2.81Å; L479-N481 VanDerWaalsContact C-N 3.3Å; L479-N481 PolarHBondContact O-N 3.2Å; N481-K487 WeakPolarHBondContact O-CE 3.37Å; N481-K487 WeakPolarHBondContact OD1-CA 3.26Å; N481-I488 PolarHBondContact ND2-O 3.03Å; N481-I488 PolarHBondContact OD1-N 3.41Å; N481-M493 VanDerWaalsContact ND2-CE 3.27Å; N481-M493 WeakPolarHBondContact ND2-CE 3.49Å
482	F	82.2	Confident	83.1	Confident	170 Å²	170	71.3 Å²	71.3	75%	0.746	35%	0.35	S	S	*	.	H	α-helix	trans	-82.4	-32	169.7	-169.8	-96.1	0	0	0	112.8	L479 L480	L479-F482 WeakPolarHBondContact O-CB 3.41Å; L479-F482 PolarHBondContact O-N 3.08Å; L480-F482 PolarHBondContact O-N 2.93Å; L480-F482 VanDerWaalsContact O-N 3.11Å
483	F	78.2	Confident	82.9	Confident	159 Å²	159	72 Å²	72	70%	0.697	35%	0.353	S	S	*	.	H	α-helix	trans	-103.7	2.3	-172.6	-66.1	-78.6	0	0	0	114.4	L479 L480	L479-F483 HydrophobicContact CD1-CE2 4.24Å; L479-F483 WeakPolarHBondContact O-CD2 3.04Å; L480-F483 PolarHBondContact O-N 3.41Å
484	R	73.1	Confident	82.8	Confident	26 Å²	26	75.7 Å²	75.7	10%	0.098	37%	0.369	C	S	.	.			trans	-127.8	130.2	-169.3	-165.6	-179.9	-173.1	-166.8	3.8	112.2	N225 L480 H486 K487	N225-R484 PolarHBondContact OD1-NE 2.89Å; N225-R484 PolarHBondContact OD1-NH2 2.93Å; L480-R484 WeakPolarHBondContact O-CB 3.28Å; L480-R484 PolarHBondContact O-N 3.02Å; R484-H486 VanDerWaalsContact CD-O 3.27Å; R484-H486 WeakPolarHBondContact CD-O 3.32Å; R484-H486 WeakPolarHBondContact CG-O 3.4Å; R484-H486 PolarHBondContact NE-O 3.36Å; R484-K487 WeakPolarHBondContact O-CG 3.47Å
485	D	63.8	Low	82.4	Confident	168 Å²	168	72.8 Å²	72.8	90%	0.898	36%	0.357	S	S	*	.	S	Bend	trans	-65.9	-47.8	178.6	-53.8	-69.9	0	0	0	111.8	K487	D485-K487 PolarHBondContact O-N 3.32Å
486	H	72.8	Confident	82.1	Confident	100 Å²	100	69.5 Å²	69.5	46%	0.463	34%	0.336	S	S	.	.	S	Bend	trans	-85.5	94.3	173.4	-164.8	-90.1	0	0	0	111.1	D290 R484	D290-H486 IonicContact OD2-CE1 2.82Å; D290-H486 PolarHBondContact OD2-CE1 3.11Å; R484-H486 VanDerWaalsContact CD-O 3.27Å; R484-H486 WeakPolarHBondContact CD-O 3.32Å; R484-H486 WeakPolarHBondContact CG-O 3.4Å; R484-H486 PolarHBondContact NE-O 3.36Å
487	K	77.7	Confident	82.1	Confident	129 Å²	129	71.9 Å²	71.9	56%	0.561	34%	0.344	S	S	*	.	P	Polyproline II helix	trans	-75.6	136.2	-173.8	-65.5	179	-178.5	180	0	112.6	N481 R484 D485 T489	N481-K487 WeakPolarHBondContact O-CE 3.37Å; N481-K487 WeakPolarHBondContact OD1-CA 3.26Å; R484-K487 WeakPolarHBondContact O-CG 3.47Å; D485-K487 PolarHBondContact O-N 3.32Å; K487-T489 PolarHBondContact O-N 3.48Å
488	I	80.6	Confident	82	Confident	4 Å²	4	73.9 Å²	73.9	2%	0.021	35%	0.353	C	S	.	.	P	Polyproline II helix	trans	-69.7	117.7	171.8	-54.8	176.9	0	0	0	107.9	F232 L296 N481 M492 M493 M496	F232-I488 HydrophobicContact CE2-CD1 4.19Å; F232-I488 HydrophobicContact CZ-CD1 4.03Å; L296-I488 HydrophobicContact CD1-CD1 4.18Å; L296-I488 HydrophobicContact CD1-CG1 4.43Å; N481-I488 PolarHBondContact ND2-O 3.03Å; N481-I488 PolarHBondContact OD1-N 3.41Å; I488-M492 HydrophobicContact CG2-CB 3.8Å; I488-M493 HydrophobicContact CB-CE 4.45Å; I488-M493 HydrophobicContact CG2-CE 4.42Å; I488-M493 HydrophobicContact CG2-CG 3.73Å; I488-M493 VanDerWaalsContact O-CE 3.26Å; I488-M493 WeakPolarHBondContact O-CE 3.26Å; I488-M496 HydrophobicContact CD1-CE 4.21Å; I488-M496 HydrophobicContact CG2-CE 3.65Å
489	T	83.3	Confident	81.7	Confident	60 Å²	60	66.1 Å²	66.1	37%	0.368	32%	0.319	S	S	.	.	P	Polyproline II helix	trans	-72.9	155.3	178.2	69.2	0	0	0	0	111.5	K487 K491 M492 M493	K487-T489 PolarHBondContact O-N 3.48Å; T489-K491 PolarHBondContact O-N 2.97Å; T489-K491 VanDerWaalsContact O-N 3.17Å; T489-M492 HydrophobicContact CG2-CE 4.5Å; T489-M492 HydrophobicContact CG2-SD 3.9Å; T489-M492 PolarHBondContact N-SD 2.64Å; T489-M492 VanDerWaalsContact N-SD 3.37Å; T489-M492 WeakPolarHBondContact O-CA 3.48Å; T489-M492 WeakPolarHBondContact O-CB 3.44Å; T489-M492 PolarHBondContact O-N 3.34Å; T489-M492 VanDerWaalsContact OG1-CG 3.25Å; T489-M492 WeakPolarHBondContact OG1-CG 3.4Å; T489-M492 PolarHBondContact OG1-N 3.37Å; T489-M492 PolarHBondContact OG1-SD 3.2Å; T489-M492 VanDerWaalsContact OG1-SD 3.34Å; T489-M493 WeakPolarHBondContact O-CG 3.45Å; T489-M493 PolarHBondContact O-N 3.1Å
490	P	83.1	Confident	81.3	Confident	99 Å²	99	62 Å²	62	64%	0.643	30%	0.299	S	S	*	.	H	α-helix	trans	-56.6	-30.4	174	-27.2	36.2	0	0	0	113.7	M493 F494	P490-M493 PolarHBondContact O-N 3.25Å; P490-F494 PolarHBondContact O-N 3.44Å
491	K	82.1	Confident	81.3	Confident	83 Å²	83	61.4 Å²	61.4	36%	0.361	30%	0.295	S	S	.	.	H	α-helix	trans	-63.6	-46.7	172	-65.4	-164.5	-175.5	-166.7	0	111.3	T489 M493 F494 I495 M550 E553	T489-K491 PolarHBondContact O-N 2.97Å; T489-K491 VanDerWaalsContact O-N 3.17Å; K491-M493 VanDerWaalsContact C-N 3.34Å; K491-M493 PolarHBondContact O-N 3.04Å; K491-F494 PolarHBondContact O-N 3.02Å; K491-I495 WeakPolarHBondContact O-CG1 3.28Å; K491-I495 PolarHBondContact O-N 3.13Å; K491-M550 HydrophobicContact CB-CE 3.7Å; K491-M550 HydrophobicContact CD-CE 4.43Å; K491-M550 HydrophobicContact CG-CE 4.14Å; K491-E553 IonicContact NZ-OE1 3.38Å; K491-E553 PolarHBondContact NZ-OE1 3.3Å; K491-E553 IonicContact NZ-OE2 3.65Å; K491-E553 PolarHBondContact NZ-OE2 3.07Å
492	M	80.8	Confident	81.3	Confident	37 Å²	37	60.1 Å²	60.1	18%	0.182	29%	0.288	C	S	.	.	H	α-helix	trans	-61.4	-40	174.5	-65.9	157.6	166.9	0	0	111.8	D290 L293 I488 T489 F494 I495 M496	D290-M492 HydrophobicContact CB-CE 4.01Å; D290-M492 WeakPolarHBondContact OD2-CE 3.49Å; L293-M492 HydrophobicContact CD1-CB 4.42Å; L293-M492 HydrophobicContact CD2-CB 4.16Å; L293-M492 HydrophobicContact CD2-CG 3.98Å; I488-M492 HydrophobicContact CG2-CB 3.8Å; T489-M492 HydrophobicContact CG2-CE 4.5Å; T489-M492 HydrophobicContact CG2-SD 3.9Å; T489-M492 PolarHBondContact N-SD 2.64Å; T489-M492 VanDerWaalsContact N-SD 3.37Å; T489-M492 WeakPolarHBondContact O-CA 3.48Å; T489-M492 WeakPolarHBondContact O-CB 3.44Å; T489-M492 PolarHBondContact O-N 3.34Å; T489-M492 VanDerWaalsContact OG1-CG 3.25Å; T489-M492 WeakPolarHBondContact OG1-CG 3.4Å; T489-M492 PolarHBondContact OG1-N 3.37Å; T489-M492 PolarHBondContact OG1-SD 3.2Å; T489-M492 VanDerWaalsContact OG1-SD 3.34Å; M492-F494 PolarHBondContact O-N 2.98Å; M492-I495 PolarHBondContact O-N 3.47Å; M492-M496 WeakPolarHBondContact O-CG 3.44Å; M492-M496 PolarHBondContact O-N 3.48Å
493	M	87.6	Confident	81.2	Confident	17 Å²	17	52.1 Å²	52.1	8%	0.084	25%	0.254	C	S	.	.	H	α-helix	trans	-60.8	-43.8	175	-59.2	-179.6	-161.1	0	0	112.2	I473 F474 S477 N481 I488 T489 P490 K491 I495 M496 W497	I473-M493 HydrophobicContact CG2-CB 4.33Å; F474-M493 HydrophobicContact CD1-CB 3.77Å; F474-M493 HydrophobicContact CD1-SD 4.13Å; F474-M493 HydrophobicContact CE1-CB 3.7Å; S477-M493 VanDerWaalsContact CB-SD 3.55Å; N481-M493 VanDerWaalsContact ND2-CE 3.27Å; N481-M493 WeakPolarHBondContact ND2-CE 3.49Å; I488-M493 HydrophobicContact CB-CE 4.45Å; I488-M493 HydrophobicContact CG2-CE 4.42Å; I488-M493 HydrophobicContact CG2-CG 3.73Å; I488-M493 VanDerWaalsContact O-CE 3.26Å; I488-M493 WeakPolarHBondContact O-CE 3.26Å; T489-M493 WeakPolarHBondContact O-CG 3.45Å; T489-M493 PolarHBondContact O-N 3.1Å; P490-M493 PolarHBondContact O-N 3.25Å; K491-M493 VanDerWaalsContact C-N 3.34Å; K491-M493 PolarHBondContact O-N 3.04Å; M493-I495 VanDerWaalsContact C-N 3.33Å; M493-I495 PolarHBondContact O-N 3.41Å; M493-M496 HydrophobicContact CG-CE 4.44Å; M493-M496 PolarHBondContact O-N 3.07Å; M493-W497 WeakPolarHBondContact O-CB 3.34Å; M493-W497 PolarHBondContact O-N 3.48Å
494	F	87.1	Confident	81	Confident	78 Å²	78	44.8 Å²	44.8	34%	0.342	22%	0.223	S	C	.	.	H	α-helix	trans	-63.8	-38.6	176.7	-170.2	-94	0	0	0	112.1	F474 P490 K491 M492 W497 F498 L546 M550	F474-F494 HydrophobicContact CZ-CD2 4.48Å; P490-F494 PolarHBondContact O-N 3.44Å; K491-F494 PolarHBondContact O-N 3.02Å; M492-F494 PolarHBondContact O-N 2.98Å; F494-W497 AromaticContact CD2-CE3 3.99Å; F494-W497 HydrophobicContact CD2-CE3 3.99Å; F494-W497 HydrophobicContact CD2-CZ3 4.33Å; F494-W497 AromaticContact CE2-CE3 3.68Å; F494-W497 HydrophobicContact CE2-CE3 3.68Å; F494-W497 AromaticContact CE2-CZ3 3.56Å; F494-W497 HydrophobicContact CE2-CZ3 3.56Å; F494-W497 HydrophobicContact CZ-CE3 4.05Å; F494-W497 AromaticContact CZ-CZ3 3.75Å; F494-W497 HydrophobicContact CZ-CZ3 3.75Å; F494-W497 PolarHBondContact O-N 3.34Å; F494-F498 WeakPolarHBondContact O-CB 3.35Å; F494-F498 PolarHBondContact O-N 2.89Å; F494-L546 HydrophobicContact CD1-CD2 4.4Å; F494-L546 HydrophobicContact CE1-CD1 4.04Å; F494-L546 HydrophobicContact CE1-CD2 3.92Å; F494-M550 HydrophobicContact CD1-SD 4.25Å
495	I	83.6	Confident	81.4	Confident	17 Å²	17	44.6 Å²	44.6	9%	0.087	22%	0.224	C	C	.	.	H	α-helix	trans	-63.1	-49.3	173.7	-67.7	165.8	0	0	0	110.6	F284 L293 K491 M492 M493 W497 F498 S499 M550	F284-I495 HydrophobicContact CE1-CG2 3.56Å; F284-I495 HydrophobicContact CZ-CG2 3.45Å; F284-I495 VanDerWaalsContact CZ-CG2 3.45Å; L293-I495 HydrophobicContact CD2-CB 4.38Å; L293-I495 HydrophobicContact CD2-CD1 4.41Å; L293-I495 HydrophobicContact CD2-CG2 4.04Å; K491-I495 WeakPolarHBondContact O-CG1 3.28Å; K491-I495 PolarHBondContact O-N 3.13Å; M492-I495 PolarHBondContact O-N 3.47Å; M493-I495 VanDerWaalsContact C-N 3.33Å; M493-I495 PolarHBondContact O-N 3.41Å; I495-W497 PolarHBondContact O-N 3.11Å; I495-F498 PolarHBondContact O-N 3.46Å; I495-S499 WeakPolarHBondContact O-CB 3.5Å; I495-S499 PolarHBondContact O-N 3.4Å; I495-S499 PolarHBondContact O-OG 2.9Å; I495-S499 VanDerWaalsContact O-OG 3.1Å; I495-M550 HydrophobicContact CD1-CE 3.85Å; I495-M550 HydrophobicContact CD1-SD 4.1Å; I495-M550 HydrophobicContact CG1-CE 3.8Å; I495-M550 HydrophobicContact CG1-SD 3.76Å
496	M	85.3	Confident	82.5	Confident	2 Å²	2	36.7 Å²	36.7	1%	0.01	18%	0.181	C	C	.	.	H	α-helix	trans	-61.4	-30.3	177.1	-67	-170.1	-60.2	0	0	113.7	F232 L293 V297 R469 I473 S477 I488 M492 M493	F232-M496 HydrophobicContact CZ-CE 4.26Å; L293-M496 HydrophobicContact CD1-CG 3.28Å; L293-M496 HydrophobicContact CD1-SD 3.82Å; V297-M496 HydrophobicContact CG2-CB 4.38Å; V297-M496 HydrophobicContact CG2-CG 3.69Å; V297-M496 HydrophobicContact CG2-SD 4.35Å; R469-M496 PolarHBondContact NE-O 2.76Å; R469-M496 PolarHBondContact NH2-O 3.29Å; I473-M496 HydrophobicContact CD1-CB 4.43Å; I473-M496 HydrophobicContact CG1-CB 4.5Å; I473-M496 HydrophobicContact CG2-CB 4.06Å; I473-M496 HydrophobicContact CG2-CE 4.05Å; S477-M496 WeakPolarHBondContact OG-CE 3.29Å; I488-M496 HydrophobicContact CD1-CE 4.21Å; I488-M496 HydrophobicContact CG2-CE 3.65Å; M492-M496 WeakPolarHBondContact O-CG 3.44Å; M492-M496 PolarHBondContact O-N 3.48Å; M493-M496 HydrophobicContact CG-CE 4.44Å; M493-M496 PolarHBondContact O-N 3.07Å
497	W	88.9	Confident	82.9	Confident	61 Å²	61	32.1 Å²	32.1	23%	0.231	16%	0.16	C	C	.	.	H	α-helix	trans	-69.2	-55.1	173.1	172.9	69	0	0	0	111.1	L466 R469 A470 F474 M493 F494 I495 S499 G500	L466-W497 PolarHBondContact O-NE1 3.45Å; R469-W497 VanDerWaalsContact C-CD1 3.45Å; R469-W497 WeakPolarHBondContact CG-O 3.45Å; A470-W497 VanDerWaalsContact CA-CD1 3.47Å; F474-W497 HydrophobicContact CE2-CB 4.36Å; F474-W497 HydrophobicContact CE2-CG 4.21Å; F474-W497 HydrophobicContact CZ-CB 4.24Å; F474-W497 HydrophobicContact CZ-CG 4.44Å; M493-W497 WeakPolarHBondContact O-CB 3.34Å; M493-W497 PolarHBondContact O-N 3.48Å; F494-W497 AromaticContact CD2-CE3 3.99Å; F494-W497 HydrophobicContact CD2-CE3 3.99Å; F494-W497 HydrophobicContact CD2-CZ3 4.33Å; F494-W497 AromaticContact CE2-CE3 3.68Å; F494-W497 HydrophobicContact CE2-CE3 3.68Å; F494-W497 AromaticContact CE2-CZ3 3.56Å; F494-W497 HydrophobicContact CE2-CZ3 3.56Å; F494-W497 HydrophobicContact CZ-CE3 4.05Å; F494-W497 AromaticContact CZ-CZ3 3.75Å; F494-W497 HydrophobicContact CZ-CZ3 3.75Å; F494-W497 PolarHBondContact O-N 3.34Å; I495-W497 PolarHBondContact O-N 3.11Å; W497-S499 PolarHBondContact O-N 2.89Å; W497-G500 PolarHBondContact O-N 3.31Å
498	F	86.5	Confident	82.9	Confident	41 Å²	41	26.1 Å²	26.1	18%	0.18	13%	0.134	C	C	.	.	H	α-helix	trans	-67	-34.6	-176.5	-168.4	-87.5	0	0	0	113	F494 I495 G500 L539 L546	F494-F498 WeakPolarHBondContact O-CB 3.35Å; F494-F498 PolarHBondContact O-N 2.89Å; I495-F498 PolarHBondContact O-N 3.46Å; F498-G500 PolarHBondContact O-N 2.99Å; F498-L539 HydrophobicContact CD2-CD2 4.26Å; F498-L539 HydrophobicContact CE1-CB 4.32Å; F498-L539 HydrophobicContact CE1-CD2 4.38Å; F498-L539 WeakPolarHBondContact CE1-O 3.31Å; F498-L539 HydrophobicContact CE2-CD2 3.78Å; F498-L539 HydrophobicContact CZ-CD2 3.86Å; F498-L546 HydrophobicContact CB-CD2 3.81Å; F498-L546 HydrophobicContact CD1-CD2 3.39Å; F498-L546 HydrophobicContact CD2-CD2 3.73Å; F498-L546 HydrophobicContact CE1-CB 4.48Å; F498-L546 HydrophobicContact CE1-CD2 3.8Å; F498-L546 HydrophobicContact CE2-CD2 4.11Å; F498-L546 HydrophobicContact CG-CD2 3.34Å; F498-L546 HydrophobicContact CZ-CD2 4.14Å
499	S	80.1	Confident	82.8	Confident	1 Å²	1	26 Å²	26	1%	0.007	13%	0.134	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.9	9.9	-179.9	82.3	0	0	0	0	114.2	T280 I495 W497 L501	T280-S499 PolarHBondContact OG1-O 3.4Å; T280-S499 VanDerWaalsContact OG1-O 3.08Å; I495-S499 WeakPolarHBondContact O-CB 3.5Å; I495-S499 PolarHBondContact O-N 3.4Å; I495-S499 PolarHBondContact O-OG 2.9Å; I495-S499 VanDerWaalsContact O-OG 3.1Å; W497-S499 PolarHBondContact O-N 2.89Å; S499-L501 PolarHBondContact O-N 3.28Å
500	G	79.7	Confident	82.8	Confident	5 Å²	5	23.2 Å²	23.2	5%	0.052	12%	0.116	C	C	.	.			trans	-77.8	59.8	177.6	0	0	0	0	0	113	W497 F498	W497-G500 PolarHBondContact O-N 3.31Å; F498-G500 PolarHBondContact O-N 2.99Å
501	L	84.3	Confident	82.3	Confident	4 Å²	4	19.4 Å²	19.4	2%	0.021	9%	0.091	C	C	.	.			trans	-65.9	144.7	-178.6	-48.3	-177.6	0	0	0	110.6	V275 D276 A279 S499 L539	V275-L501 CarbonylContact C-O 3.56Å; V275-L501 WeakPolarHBondContact CA-O 3.48Å; D276-L501 PolarHBondContact N-O 3.06Å; A279-L501 HydrophobicContact CB-CD1 3.78Å; S499-L501 PolarHBondContact O-N 3.28Å; L501-L539 HydrophobicContact CD2-CB 3.56Å
502	R	87.4	Confident	81.9	Confident	1 Å²	1	19.7 Å²	19.7	0%	0.004	9%	0.093	C	C	.	.			trans	-96.7	124.3	173	-54.4	-56.2	-178	173.8	4.3	108.6	I272 S273 A274 V465 I531 V532 T535	I272-R502 WeakPolarHBondContact O-CD 3.24Å; I272-R502 PolarHBondContact O-NE 3.42Å; I272-R502 PolarHBondContact O-NH1 3.42Å; S273-R502 PolarHBondContact O-NH1 2.84Å; A274-R502 WeakPolarHBondContact O-CD 3.43Å; A274-R502 PolarHBondContact O-NH1 3.11Å; V465-R502 HydrophobicContact CG1-CG 4.48Å; R502-I531 HydrophobicContact CG-CG2 4.08Å; R502-V532 HydrophobicContact CB-CG2 3.99Å; R502-V532 WeakPolarHBondContact O-CG1 3.31Å; R502-T535 WeakPolarHBondContact CB-OG1 3.4Å; R502-T535 HydrophobicContact CG-CG2 4.15Å; R502-T535 PolarHBondContact N-OG1 3.46Å
503	G	79.1	Confident	81.4	Confident	3 Å²	3	18 Å²	18	3%	0.031	9%	0.085	C	C	.	.			trans	-90.3	-166.3	-179.9	0	0	0	0	0	113.7	D276 P506 V532	D276-G503 VanDerWaalsContact CB-CA 3.45Å; D276-G503 WeakPolarHBondContact OD2-CA 3.27Å; G503-P506 WeakPolarHBondContact O-CD 3.32Å; G503-V532 WeakPolarHBondContact O-CG2 3.49Å
504	A	74.6	Confident	80.1	Confident	5 Å²	5	20 Å²	20	4%	0.041	11%	0.11	C	C	.	.	H	α-helix	trans	-83.2	-10.4	-179.4	0	0	0	0	0	114.9	V438 L442 Y507 A508	V438-A504 HydrophobicContact CG1-CB 3.22Å; L442-A504 HydrophobicContact CD1-CB 3.94Å; A504-Y507 WeakPolarHBondContact O-CB 3.19Å; A504-Y507 PolarHBondContact O-N 3.29Å; A504-A508 PolarHBondContact O-N 3.17Å
505	I	81.8	Confident	78.9	Confident	22 Å²	22	17 Å²	17	11%	0.113	10%	0.097	C	C	.	.	H	α-helix	trans	-61.7	-48.9	173.7	-69.6	167.4	0	0	0	111.7	F201 L206 I210 D305 I309 Y507 A508 L509	F201-I505 HydrophobicContact CZ-CG1 4.12Å; L206-I505 HydrophobicContact CD1-CG1 4.4Å; I210-I505 HydrophobicContact CD1-CD1 4.36Å; D305-I505 HydrophobicContact CB-CD1 3.93Å; D305-I505 WeakPolarHBondContact OD2-CD1 3.48Å; I309-I505 HydrophobicContact CD1-CG2 4.07Å; I309-I505 HydrophobicContact CG1-CG2 4.41Å; I505-Y507 PolarHBondContact O-N 2.9Å; I505-A508 PolarHBondContact O-N 2.9Å; I505-L509 WeakPolarHBondContact O-CB 3.08Å; I505-L509 PolarHBondContact O-N 3.39Å
506	P	85.7	Confident	77.4	Confident	1 Å²	1	24.4 Å²	24.4	1%	0.006	13%	0.132	C	C	.	.	H	α-helix	trans	-46	-47.3	166.3	-28.8	27.5	0	0	0	113.5	L271 I272 A274 G503 L509 S510 T528 V532	L271-P506 HydrophobicContact CD1-CB 4.43Å; L271-P506 WeakPolarHBondContact O-CA 3.29Å; L271-P506 WeakPolarHBondContact O-CB 3.38Å; L271-P506 WeakPolarHBondContact O-CG 3.46Å; I272-P506 HydrophobicContact CD1-CB 4.02Å; A274-P506 HydrophobicContact CB-CG 3.91Å; G503-P506 WeakPolarHBondContact O-CD 3.32Å; P506-L509 PolarHBondContact O-N 2.92Å; P506-S510 WeakPolarHBondContact O-CB 3.4Å; P506-S510 PolarHBondContact O-N 2.88Å; P506-T528 HydrophobicContact CB-CG2 3.9Å; P506-V532 HydrophobicContact CB-CG2 4.4Å
507	Y	81.8	Confident	76.6	Confident	5 Å²	5	27.6 Å²	27.6	2%	0.02	15%	0.152	C	C	.	.	H	α-helix	trans	-63.2	-52.4	-177.3	170.6	-122.8	0	0	0	112.3	L442 S445 F449 A504 I505 L509 S510 L511 I529	L442-Y507 HydrophobicContact CB-CD1 4.22Å; L442-Y507 HydrophobicContact CD1-CD1 3.8Å; L442-Y507 HydrophobicContact CD1-CG 3.89Å; L442-Y507 HydrophobicContact CG-CD1 4.22Å; S445-Y507 WeakPolarHBondContact CB-OH 3.46Å; S445-Y507 PolarHBondContact OG-OH 2.89Å; F449-Y507 WeakPolarHBondContact CE2-OH 3.38Å; A504-Y507 WeakPolarHBondContact O-CB 3.19Å; A504-Y507 PolarHBondContact O-N 3.29Å; I505-Y507 PolarHBondContact O-N 2.9Å; Y507-L509 VanDerWaalsContact C-N 3.28Å; Y507-L509 PolarHBondContact O-N 2.85Å; Y507-S510 WeakPolarHBondContact O-CB 3.42Å; Y507-S510 PolarHBondContact O-N 3.3Å; Y507-S510 VanDerWaalsContact O-N 3.09Å; Y507-S510 PolarHBondContact O-OG 3.28Å; Y507-L511 HydrophobicContact CE1-CD1 4.2Å; Y507-L511 HydrophobicContact CE2-CD1 4.11Å; Y507-L511 HydrophobicContact CE2-CD2 3.89Å; Y507-L511 HydrophobicContact CE2-CG 3.91Å; Y507-L511 PolarHBondContact O-N 3.24Å; Y507-I529 HydrophobicContact CD2-CD1 4.16Å; Y507-I529 HydrophobicContact CD2-CG1 3.56Å; Y507-I529 HydrophobicContact CE2-CD1 3.6Å; Y507-I529 HydrophobicContact CE2-CG1 3.55Å; Y507-I529 HydrophobicContact CG-CG1 4.34Å
508	A	78	Confident	75.6	Confident	2 Å²	2	29.1 Å²	29.1	2%	0.017	16%	0.164	C	C	.	.	H	α-helix	trans	-65	-33.7	-179.2	0	0	0	0	0	112.7	F201 F202 A504 I505 S510 L511 H512	F201-A508 HydrophobicContact CB-CB 4.26Å; F201-A508 HydrophobicContact CD1-CB 3.28Å; F201-A508 HydrophobicContact CD2-CB 3.67Å; F201-A508 HydrophobicContact CE1-CB 3.28Å; F201-A508 HydrophobicContact CE2-CB 3.68Å; F201-A508 HydrophobicContact CG-CB 3.46Å; F201-A508 VanDerWaalsContact CG-CB 3.46Å; F201-A508 HydrophobicContact CZ-CB 3.49Å; F201-A508 VanDerWaalsContact CZ-CB 3.49Å; F202-A508 HydrophobicContact CE2-CB 4.48Å; A504-A508 PolarHBondContact O-N 3.17Å; I505-A508 PolarHBondContact O-N 2.9Å; A508-S510 VanDerWaalsContact C-N 3.34Å; A508-L511 PolarHBondContact O-N 3.42Å; A508-H512 PolarHBondContact O-N 2.95Å
509	L	78.2	Confident	74.8	Confident	3 Å²	3	32.6 Å²	32.6	2%	0.016	18%	0.181	C	C	.	.	H	α-helix	trans	-66.1	-36.2	173.1	-171	55.9	0	0	0	111.9	F202 L271 I309 T312 I505 P506 Y507 L511 H512 L513	F202-L509 HydrophobicContact CZ-CB 4.17Å; F202-L509 HydrophobicContact CZ-CD1 3.97Å; L271-L509 HydrophobicContact CB-CB 4.24Å; L271-L509 HydrophobicContact CB-CD2 3.56Å; L271-L509 HydrophobicContact CB-CG 3.82Å; I309-L509 HydrophobicContact CB-CD2 4.45Å; I309-L509 HydrophobicContact CG1-CD2 3.88Å; T312-L509 HydrophobicContact CG2-CD1 4.26Å; T312-L509 HydrophobicContact CG2-CD2 4.09Å; T312-L509 HydrophobicContact CG2-CG 4.12Å; I505-L509 WeakPolarHBondContact O-CB 3.08Å; I505-L509 PolarHBondContact O-N 3.39Å; P506-L509 PolarHBondContact O-N 2.92Å; Y507-L509 VanDerWaalsContact C-N 3.28Å; Y507-L509 PolarHBondContact O-N 2.85Å; L509-L511 PolarHBondContact O-N 2.88Å; L509-H512 PolarHBondContact O-N 2.93Å; L509-L513 PolarHBondContact O-N 3.42Å; L509-L513 VanDerWaalsContact O-N 3.11Å
510	S	82.4	Confident	74.6	Confident	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-63.6	-22.6	173.1	84	0	0	0	0	114.2	P506 Y507 A508	P506-S510 WeakPolarHBondContact O-CB 3.4Å; P506-S510 PolarHBondContact O-N 2.88Å; Y507-S510 WeakPolarHBondContact O-CB 3.42Å; Y507-S510 PolarHBondContact O-N 3.3Å; Y507-S510 VanDerWaalsContact O-N 3.09Å; Y507-S510 PolarHBondContact O-OG 3.28Å; A508-S510 VanDerWaalsContact C-N 3.34Å
511	L	73.9	Confident	74.5	Confident	20 Å²	20	38.3 Å²	38.3	11%	0.105	20%	0.201	C	C	.	.	H	α-helix	trans	-85.8	-28.8	174.1	-61.4	-178.6	0	0	0	113.7	F196 P198 F449 Y507 A508 L509	F196-L511 HydrophobicContact CD1-CD1 3.69Å; F196-L511 HydrophobicContact CE1-CD1 4.22Å; P198-L511 HydrophobicContact CB-CB 4.36Å; P198-L511 HydrophobicContact CG-CB 3.83Å; F449-L511 HydrophobicContact CE1-CD2 3.73Å; F449-L511 HydrophobicContact CE2-CD2 4.35Å; F449-L511 HydrophobicContact CZ-CD1 4.22Å; F449-L511 HydrophobicContact CZ-CD2 3.55Å; Y507-L511 HydrophobicContact CE1-CD1 4.2Å; Y507-L511 HydrophobicContact CE2-CD1 4.11Å; Y507-L511 HydrophobicContact CE2-CD2 3.89Å; Y507-L511 HydrophobicContact CE2-CG 3.91Å; Y507-L511 PolarHBondContact O-N 3.24Å; A508-L511 PolarHBondContact O-N 3.42Å; L509-L511 PolarHBondContact O-N 2.88Å
512	H	73.1	Confident	74.3	Confident	88 Å²	88	40.1 Å²	40.1	41%	0.407	21%	0.21	S	C	.	.	H	α-helix	trans	-79.1	-25.6	178	-170.3	76.5	0	0	0	112.2	P198 F202 A508 L509 G514	P198-H512 HydrophobicContact CB-CB 4.43Å; F202-H512 HydrophobicContact CD2-CB 4.25Å; F202-H512 HydrophobicContact CE2-CB 3.66Å; F202-H512 HydrophobicContact CZ-CB 4.42Å; A508-H512 PolarHBondContact O-N 2.95Å; L509-H512 PolarHBondContact O-N 2.93Å; H512-G514 PolarHBondContact O-N 2.85Å
513	L	70.5	Confident	74.1	Confident	1 Å²	1	40.4 Å²	40.4	1%	0.005	21%	0.211	C	C	.	.			trans	-49.8	121.1	179.9	-137.6	69.5	0	0	0	112.1	A267 L271 T312 E316 L509 L515 R521 I524	A267-L513 HydrophobicContact CB-CD1 4.37Å; A267-L513 HydrophobicContact CB-CD2 4.35Å; L271-L513 HydrophobicContact CD2-CD1 4.09Å; L271-L513 HydrophobicContact CD2-CD2 3.68Å; L271-L513 HydrophobicContact CD2-CG 4.5Å; T312-L513 HydrophobicContact CG2-CD1 3.43Å; T312-L513 VanDerWaalsContact CG2-CD1 3.43Å; E316-L513 HydrophobicContact CG-CD1 4.3Å; E316-L513 WeakPolarHBondContact OE1-CA 3.29Å; E316-L513 WeakPolarHBondContact OE1-CD1 3.35Å; E316-L513 WeakPolarHBondContact OE1-CG 3.49Å; L509-L513 PolarHBondContact O-N 3.42Å; L509-L513 VanDerWaalsContact O-N 3.11Å; L513-L515 HydrophobicContact CB-CG 4.39Å; L513-L515 HydrophobicContact CD2-CD1 3.77Å; L513-L515 HydrophobicContact CD2-CG 3.99Å; L513-L515 HydrophobicContact CG-CD1 4.42Å; L513-L515 HydrophobicContact CG-CG 4.09Å; L513-L515 PolarHBondContact O-N 2.81Å; L513-R521 WeakPolarHBondContact O-CD 3.11Å; L513-I524 HydrophobicContact CD2-CD1 4.33Å; L513-I524 HydrophobicContact CD2-CG2 4.38Å
514	G	60.5	Low	74.4	Confident	59 Å²	59	40.2 Å²	40.2	61%	0.608	21%	0.21	S	C	*	.			trans	-77.6	29.8	-167.7	0	0	0	0	0	114.9	E316 H512 E516	E316-G514 PolarHBondContact OE1-N 3.44Å; H512-G514 PolarHBondContact O-N 2.85Å; G514-E516 PolarHBondContact O-N 2.68Å
515	L	60.7	Low	74.9	Confident	16 Å²	16	40.2 Å²	40.2	8%	0.084	21%	0.21	C	C	.	.	P	Polyproline II helix	trans	-75.9	120	-167.1	-60.4	-173.2	0	0	0	113.4	D264 L513 K520 I524	D264-L515 HydrophobicContact CB-CD1 4.3Å; D264-L515 HydrophobicContact CB-CD2 4.39Å; L513-L515 HydrophobicContact CB-CG 4.39Å; L513-L515 HydrophobicContact CD2-CD1 3.77Å; L513-L515 HydrophobicContact CD2-CG 3.99Å; L513-L515 HydrophobicContact CG-CD1 4.42Å; L513-L515 HydrophobicContact CG-CG 4.09Å; L513-L515 PolarHBondContact O-N 2.81Å; L515-K520 HydrophobicContact CB-CB 4.43Å; L515-K520 HydrophobicContact CD1-CB 4.38Å; L515-I524 HydrophobicContact CD1-CD1 3.47Å; L515-I524 VanDerWaalsContact CD1-CD1 3.47Å
516	E	53.8	Low	75.1	Confident	173 Å²	173	39.4 Å²	39.4	81%	0.808	21%	0.206	S	C	*	.	S	Bend	trans	-96.1	143.4	159.9	-60	-167.1	160.3	0	0	110.7	G514 K520	G514-E516 PolarHBondContact O-N 2.68Å; E516-K520 PolarHBondContact O-NZ 2.84Å
517	P	68.3	Low	75.3	Confident	68 Å²	68	39.4 Å²	39.4	44%	0.442	21%	0.206	S	C	.	.	S	Bend	cis	-76.3	165.6	-10.5	34	-36.6	0	0	0	112.9	E519 K520	P517-E519 PolarHBondContact O-N 3.33Å; P517-K520 WeakPolarHBondContact O-CB 3.48Å; P517-K520 PolarHBondContact O-N 2.98Å
518	I	67.8	Low	75.6	Confident	94 Å²	94	39.1 Å²	39.1	48%	0.482	21%	0.205	S	C	.	.	H	α-helix	trans	-56.3	-27.6	-173.1	-163.9	163.8	0	0	0	114.9	K520 R521 Q522	I518-K520 VanDerWaalsContact C-N 3.32Å; I518-K520 PolarHBondContact O-N 3.18Å; I518-R521 PolarHBondContact O-N 3.26Å; I518-R521 VanDerWaalsContact O-N 3.17Å; I518-Q522 PolarHBondContact O-N 2.99Å
519	E	70	Confident	76.1	Confident	114 Å²	114	39.3 Å²	39.3	53%	0.533	21%	0.206	S	C	.	.	H	α-helix	trans	-61	-37.4	177.6	-64.2	171	-177.3	0	0	112.4	P517 R521 Q522 L523	P517-E519 PolarHBondContact O-N 3.33Å; E519-R521 VanDerWaalsContact C-N 3.35Å; E519-R521 PolarHBondContact O-N 2.72Å; E519-Q522 PolarHBondContact O-N 2.87Å; E519-L523 PolarHBondContact O-N 3.33Å
520	K	76.1	Confident	76.7	Confident	28 Å²	28	41.3 Å²	41.3	12%	0.122	22%	0.216	C	C	.	.	H	α-helix	trans	-62.2	-43.1	174.5	-68.2	-177.8	179.6	175.4	0	111.3	Y258 D264 L515 E516 P517 I518 Q522 L523 I524	Y258-K520 HydrophobicContact CE1-CG 4.36Å; D264-K520 IonicContact OD1-NZ 3.86Å; D264-K520 WeakPolarHBondContact OD2-CD 3.45Å; D264-K520 VanDerWaalsContact OD2-CE 3.28Å; D264-K520 WeakPolarHBondContact OD2-CE 3.31Å; D264-K520 IonicContact OD2-NZ 2.75Å; D264-K520 PolarHBondContact OD2-NZ 3.1Å; L515-K520 HydrophobicContact CB-CB 4.43Å; L515-K520 HydrophobicContact CD1-CB 4.38Å; E516-K520 PolarHBondContact O-NZ 2.84Å; P517-K520 WeakPolarHBondContact O-CB 3.48Å; P517-K520 PolarHBondContact O-N 2.98Å; I518-K520 VanDerWaalsContact C-N 3.32Å; I518-K520 PolarHBondContact O-N 3.18Å; K520-Q522 VanDerWaalsContact C-N 3.34Å; K520-L523 PolarHBondContact O-N 3.43Å; K520-I524 WeakPolarHBondContact O-CB 3.38Å; K520-I524 PolarHBondContact O-N 2.97Å
521	R	76.3	Confident	77	Confident	97 Å²	97	41.4 Å²	41.4	37%	0.366	22%	0.216	S	C	.	.	H	α-helix	trans	-66.5	-37.1	179.1	-166.2	175	68.2	-145.2	3.3	111.1	L513 I518 E519 G525	L513-R521 WeakPolarHBondContact O-CD 3.11Å; I518-R521 PolarHBondContact O-N 3.26Å; I518-R521 VanDerWaalsContact O-N 3.17Å; E519-R521 VanDerWaalsContact C-N 3.35Å; E519-R521 PolarHBondContact O-N 2.72Å; R521-G525 PolarHBondContact O-N 3.07Å
522	Q	79.9	Confident	77.8	Confident	43 Å²	43	40.4 Å²	40.4	20%	0.201	21%	0.211	C	C	.	.	H	α-helix	trans	-63.7	-45.6	171.8	-70.1	168.5	-11.6	0	0	112	P450 N452 I518 E519 K520 T526	P450-Q522 HydrophobicContact CG-CG 4.34Å; N452-Q522 PolarHBondContact ND2-OE1 3.42Å; I518-Q522 PolarHBondContact O-N 2.99Å; E519-Q522 PolarHBondContact O-N 2.87Å; K520-Q522 VanDerWaalsContact C-N 3.34Å; Q522-T526 WeakPolarHBondContact O-CB 3.34Å; Q522-T526 PolarHBondContact O-N 3.41Å; Q522-T526 PolarHBondContact O-OG1 3.46Å
523	L	83.9	Confident	78.4	Confident	6 Å²	6	38 Å²	38	3%	0.031	20%	0.201	C	C	.	.	H	α-helix	trans	-61.7	-48	176.4	174.4	62.1	0	0	0	112	Y258 E454 F457 E519 K520 T527	Y258-L523 HydrophobicContact CD1-CD2 3.62Å; Y258-L523 HydrophobicContact CD2-CD2 4.17Å; Y258-L523 HydrophobicContact CE1-CD2 4.25Å; Y258-L523 HydrophobicContact CG-CD2 3.57Å; E454-L523 HydrophobicContact CB-CD1 3.8Å; E454-L523 HydrophobicContact CG-CD1 4.04Å; F457-L523 HydrophobicContact CD1-CD1 4.06Å; F457-L523 HydrophobicContact CD1-CG 4.33Å; F457-L523 HydrophobicContact CE1-CD1 4.5Å; F457-L523 HydrophobicContact CE1-CG 4.31Å; F457-L523 HydrophobicContact CG-CD1 4.42Å; E519-L523 PolarHBondContact O-N 3.33Å; K520-L523 PolarHBondContact O-N 3.43Å; L523-T527 VanDerWaalsContact O-CB 3.32Å; L523-T527 WeakPolarHBondContact O-CB 3.2Å; L523-T527 PolarHBondContact O-N 3.49Å; L523-T527 PolarHBondContact O-OG1 3.18Å
524	I	85	Confident	79.3	Confident	0 Å²	0	40.7 Å²	40.7	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-64.5	-46	178.6	-87.1	174.2	0	0	0	111.8	M260 F268 L513 L515 K520 T527 T528	M260-I524 HydrophobicContact CE-CD1 3.39Å; M260-I524 HydrophobicContact CE-CG1 4.06Å; M260-I524 HydrophobicContact SD-CD1 4.21Å; M260-I524 HydrophobicContact SD-CG1 4.48Å; F268-I524 HydrophobicContact CB-CD1 4.21Å; F268-I524 HydrophobicContact CD2-CB 4.22Å; F268-I524 HydrophobicContact CD2-CD1 4.09Å; F268-I524 HydrophobicContact CD2-CG1 3.65Å; F268-I524 HydrophobicContact CD2-CG2 3.88Å; F268-I524 HydrophobicContact CE2-CG1 4.19Å; F268-I524 HydrophobicContact CE2-CG2 4.26Å; F268-I524 HydrophobicContact CG-CG1 4.4Å; L513-I524 HydrophobicContact CD2-CD1 4.33Å; L513-I524 HydrophobicContact CD2-CG2 4.38Å; L515-I524 HydrophobicContact CD1-CD1 3.47Å; L515-I524 VanDerWaalsContact CD1-CD1 3.47Å; K520-I524 WeakPolarHBondContact O-CB 3.38Å; K520-I524 PolarHBondContact O-N 2.97Å; I524-T527 PolarHBondContact O-N 3.03Å; I524-T528 WeakPolarHBondContact O-CB 3.31Å; I524-T528 PolarHBondContact O-N 2.92Å; I524-T528 PolarHBondContact O-OG1 3.41Å
525	G	84.6	Confident	80.7	Confident	5 Å²	5	38.1 Å²	38.1	5%	0.052	19%	0.185	C	C	.	.	H	α-helix	trans	-62.1	-47.2	177.8	0	0	0	0	0	111.7	R521 T527 T528 I529	R521-G525 PolarHBondContact O-N 3.07Å; G525-T527 PolarHBondContact O-N 3.06Å; G525-T528 PolarHBondContact O-N 3.07Å; G525-I529 VanDerWaalsContact O-CG1 3.31Å; G525-I529 WeakPolarHBondContact O-CG1 3.38Å; G525-I529 PolarHBondContact O-N 2.95Å
526	T	86.7	Confident	81.7	Confident	4 Å²	4	37.8 Å²	37.8	3%	0.025	18%	0.183	C	C	.	.	H	α-helix	trans	-59.3	-46.6	176.4	-57.1	0	0	0	0	111.5	H451 F453 Q522 I529 I530	H451-T526 HydrophobicContact CB-CG2 3.87Å; H451-T526 PolarHBondContact ND1-OG1 3.08Å; F453-T526 HydrophobicContact CD1-CG2 3.79Å; F453-T526 HydrophobicContact CE1-CG2 3.71Å; F453-T526 HydrophobicContact CZ-CG2 4.39Å; Q522-T526 WeakPolarHBondContact O-CB 3.34Å; Q522-T526 PolarHBondContact O-N 3.41Å; Q522-T526 PolarHBondContact O-OG1 3.46Å; T526-I529 PolarHBondContact O-N 3.2Å; T526-I530 HydrophobicContact CG2-CD1 4.01Å; T526-I530 WeakPolarHBondContact O-CD1 3.29Å; T526-I530 VanDerWaalsContact O-CG1 3.28Å; T526-I530 WeakPolarHBondContact O-CG1 3.26Å; T526-I530 PolarHBondContact O-N 2.69Å; T526-I530 VanDerWaalsContact O-N 3.08Å
527	T	89.2	Confident	83	Confident	1 Å²	1	32.8 Å²	32.8	1%	0.006	16%	0.162	C	C	.	.	H	α-helix	trans	-65.4	-41.5	179.1	-56.2	0	0	0	0	111.7	F268 F457 V458 C461 L523 I524 G525 I530 I531	F268-T527 HydrophobicContact CZ-CG2 3.95Å; F457-T527 HydrophobicContact CD1-CG2 3.86Å; F457-T527 WeakPolarHBondContact CD1-OG1 3.26Å; F457-T527 HydrophobicContact CE1-CG2 3.78Å; F457-T527 WeakPolarHBondContact CE1-OG1 3.16Å; V458-T527 HydrophobicContact CG2-CG2 4.18Å; C461-T527 HydrophobicContact CB-CG2 4.05Å; L523-T527 VanDerWaalsContact O-CB 3.32Å; L523-T527 WeakPolarHBondContact O-CB 3.2Å; L523-T527 PolarHBondContact O-N 3.49Å; L523-T527 PolarHBondContact O-OG1 3.18Å; I524-T527 PolarHBondContact O-N 3.03Å; G525-T527 PolarHBondContact O-N 3.06Å; T527-I530 PolarHBondContact O-N 3.21Å; T527-I531 HydrophobicContact CG2-CD1 3.78Å; T527-I531 HydrophobicContact CG2-CG1 4.41Å; T527-I531 WeakPolarHBondContact O-CG1 3.32Å; T527-I531 PolarHBondContact O-N 2.94Å
528	T	89.9	Confident	83.8	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-61.5	-46.7	176.5	-54	0	0	0	0	111.4	F268 L271 I272 P506 I524 G525 I530 I531 V532	F268-T528 WeakPolarHBondContact CE2-OG1 3.35Å; L271-T528 HydrophobicContact CD1-CG2 4.25Å; I272-T528 HydrophobicContact CD1-CG2 4.08Å; P506-T528 HydrophobicContact CB-CG2 3.9Å; I524-T528 WeakPolarHBondContact O-CB 3.31Å; I524-T528 PolarHBondContact O-N 2.92Å; I524-T528 PolarHBondContact O-OG1 3.41Å; G525-T528 PolarHBondContact O-N 3.07Å; T528-I530 VanDerWaalsContact C-N 3.32Å; T528-I530 PolarHBondContact O-N 3.28Å; T528-I531 PolarHBondContact O-N 3.24Å; T528-V532 HydrophobicContact CG2-CG2 4.24Å; T528-V532 WeakPolarHBondContact O-CB 3.49Å; T528-V532 VanDerWaalsContact O-CG2 3.27Å; T528-V532 WeakPolarHBondContact O-CG2 3.5Å; T528-V532 PolarHBondContact O-N 3.15Å
529	I	87.9	Confident	84.6	Confident	5 Å²	5	32.6 Å²	32.6	3%	0.026	15%	0.152	C	C	.	.	H	α-helix	trans	-54.4	-47.5	174.5	-73.5	167.4	0	0	0	110.8	I446 Y507 G525 T526 V532 L533	I446-I529 HydrophobicContact CD1-CG2 3.82Å; I446-I529 HydrophobicContact CG1-CG2 3.72Å; Y507-I529 HydrophobicContact CD2-CD1 4.16Å; Y507-I529 HydrophobicContact CD2-CG1 3.56Å; Y507-I529 HydrophobicContact CE2-CD1 3.6Å; Y507-I529 HydrophobicContact CE2-CG1 3.55Å; Y507-I529 HydrophobicContact CG-CG1 4.34Å; G525-I529 VanDerWaalsContact O-CG1 3.31Å; G525-I529 WeakPolarHBondContact O-CG1 3.38Å; G525-I529 PolarHBondContact O-N 2.95Å; T526-I529 PolarHBondContact O-N 3.2Å; I529-V532 PolarHBondContact O-N 2.93Å; I529-L533 VanDerWaalsContact O-CB 3.29Å; I529-L533 WeakPolarHBondContact O-CB 3.49Å; I529-L533 PolarHBondContact O-N 2.91Å
530	I	89.6	Confident	85	Confident	46 Å²	46	27.2 Å²	27.2	24%	0.236	13%	0.127	C	C	.	.	H	α-helix	trans	-66.5	-41.7	-178.5	-61	159.4	0	0	0	111.5	F453 V458 T526 T527 T528 F534	F453-I530 HydrophobicContact CD1-CD1 4Å; F453-I530 HydrophobicContact CE1-CD1 3.95Å; V458-I530 HydrophobicContact CG1-CB 4.15Å; V458-I530 HydrophobicContact CG1-CD1 4.04Å; V458-I530 HydrophobicContact CG1-CG2 3.66Å; V458-I530 HydrophobicContact CG2-CD1 3.82Å; T526-I530 HydrophobicContact CG2-CD1 4.01Å; T526-I530 WeakPolarHBondContact O-CD1 3.29Å; T526-I530 VanDerWaalsContact O-CG1 3.28Å; T526-I530 WeakPolarHBondContact O-CG1 3.26Å; T526-I530 PolarHBondContact O-N 2.69Å; T526-I530 VanDerWaalsContact O-N 3.08Å; T527-I530 PolarHBondContact O-N 3.21Å; T528-I530 VanDerWaalsContact C-N 3.32Å; T528-I530 PolarHBondContact O-N 3.28Å; I530-F534 WeakPolarHBondContact O-CB 3.39Å; I530-F534 PolarHBondContact O-N 2.72Å
531	I	90.4	Very high	85.1	Confident	1 Å²	1	26.7 Å²	26.7	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-66	-42.7	178.1	-66.4	165.4	0	0	0	111.2	F268 I272 C461 I462 V465 R502 T527 T528 F534 T535	F268-I531 HydrophobicContact CZ-CD1 4.08Å; I272-I531 HydrophobicContact CD1-CB 4.24Å; I272-I531 HydrophobicContact CD1-CD1 4.35Å; I272-I531 HydrophobicContact CD1-CG2 3.89Å; I272-I531 HydrophobicContact CG1-CD1 4.24Å; I272-I531 HydrophobicContact CG1-CG2 4.15Å; C461-I531 HydrophobicContact CB-CD1 3.85Å; I462-I531 HydrophobicContact CG1-CG1 3.87Å; V465-I531 HydrophobicContact CG1-CG2 4.37Å; V465-I531 HydrophobicContact CG2-CD1 4.49Å; R502-I531 HydrophobicContact CG-CG2 4.08Å; T527-I531 HydrophobicContact CG2-CD1 3.78Å; T527-I531 HydrophobicContact CG2-CG1 4.41Å; T527-I531 WeakPolarHBondContact O-CG1 3.32Å; T527-I531 PolarHBondContact O-N 2.94Å; T528-I531 PolarHBondContact O-N 3.24Å; I531-F534 PolarHBondContact O-N 3.41Å; I531-T535 WeakPolarHBondContact O-CG2 3.47Å; I531-T535 PolarHBondContact O-N 2.77Å; I531-T535 PolarHBondContact O-OG1 3.4Å
532	V	89.3	Confident	85.2	Confident	0 Å²	0	23 Å²	23	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-63.5	-49.7	177	170.2	0	0	0	0	110.2	L442 R502 G503 P506 T528 I529 F534 T535 I536	L442-V532 HydrophobicContact CD1-CB 4.25Å; L442-V532 HydrophobicContact CD1-CG1 3.5Å; L442-V532 VanDerWaalsContact CD1-CG1 3.5Å; L442-V532 HydrophobicContact CD2-CG1 4.06Å; L442-V532 HydrophobicContact CG-CG1 4.44Å; R502-V532 HydrophobicContact CB-CG2 3.99Å; R502-V532 WeakPolarHBondContact O-CG1 3.31Å; G503-V532 WeakPolarHBondContact O-CG2 3.49Å; P506-V532 HydrophobicContact CB-CG2 4.4Å; T528-V532 HydrophobicContact CG2-CG2 4.24Å; T528-V532 WeakPolarHBondContact O-CB 3.49Å; T528-V532 VanDerWaalsContact O-CG2 3.27Å; T528-V532 WeakPolarHBondContact O-CG2 3.5Å; T528-V532 PolarHBondContact O-N 3.15Å; I529-V532 PolarHBondContact O-N 2.93Å; V532-F534 PolarHBondContact O-N 3.08Å; V532-T535 PolarHBondContact O-N 2.9Å; V532-T535 PolarHBondContact O-OG1 2.71Å; V532-I536 HydrophobicContact CG1-CD1 3.61Å; V532-I536 HydrophobicContact CG1-CG1 4.41Å; V532-I536 WeakPolarHBondContact O-CB 3.41Å; V532-I536 WeakPolarHBondContact O-CG1 3.29Å; V532-I536 PolarHBondContact O-N 2.87Å
533	L	86.8	Confident	85.1	Confident	38 Å²	38	21 Å²	21	20%	0.199	11%	0.112	C	C	.	.	H	α-helix	trans	-60.9	-43.8	176.2	-171.8	70.6	0	0	0	112.1	V169 I173 I446 I529 L537	V169-L533 HydrophobicContact CG1-CD1 3.69Å; I173-L533 HydrophobicContact CD1-CD1 3.92Å; I173-L533 HydrophobicContact CD1-CD2 4.48Å; I446-L533 HydrophobicContact CD1-CD1 4.49Å; I446-L533 HydrophobicContact CD1-CD2 3.84Å; I529-L533 VanDerWaalsContact O-CB 3.29Å; I529-L533 WeakPolarHBondContact O-CB 3.49Å; I529-L533 PolarHBondContact O-N 2.91Å; L533-L537 HydrophobicContact CD1-CD1 3.75Å; L533-L537 HydrophobicContact CD1-CG 3.96Å; L533-L537 HydrophobicContact CD2-CD1 4.41Å; L533-L537 HydrophobicContact CG-CD1 3.79Å; L533-L537 HydrophobicContact CG-CG 4.21Å; L533-L537 VanDerWaalsContact O-CB 3.3Å; L533-L537 WeakPolarHBondContact O-CB 3.42Å; L533-L537 VanDerWaalsContact O-CG 3.28Å; L533-L537 WeakPolarHBondContact O-CG 3.48Å; L533-L537 PolarHBondContact O-N 3.31Å
534	F	89.1	Confident	84.6	Confident	57 Å²	57	22 Å²	22	25%	0.25	12%	0.117	C	C	.	.	H	α-helix	trans	-60.1	-49.4	177.7	173.2	-100.9	0	0	0	111.5	I462 I530 I531 V532 F538	I462-F534 HydrophobicContact CD1-CD1 4.37Å; I462-F534 HydrophobicContact CD1-CG 4.28Å; I462-F534 HydrophobicContact CG1-CD1 4.47Å; I462-F534 HydrophobicContact CG2-CD1 3.95Å; I462-F534 HydrophobicContact CG2-CE1 3.62Å; I462-F534 HydrophobicContact CG2-CZ 4.2Å; I530-F534 WeakPolarHBondContact O-CB 3.39Å; I530-F534 PolarHBondContact O-N 2.72Å; I531-F534 PolarHBondContact O-N 3.41Å; V532-F534 PolarHBondContact O-N 3.08Å; F534-F538 HydrophobicContact CD2-CB 4.37Å; F534-F538 AromaticContact CD2-CD2 3.48Å; F534-F538 HydrophobicContact CD2-CD2 3.48Å; F534-F538 VanDerWaalsContact CD2-CD2 3.48Å; F534-F538 AromaticContact CD2-CE2 3.94Å; F534-F538 HydrophobicContact CD2-CE2 3.94Å; F534-F538 HydrophobicContact CD2-CG 4.03Å; F534-F538 HydrophobicContact CE2-CB 4.15Å; F534-F538 AromaticContact CE2-CD2 3.86Å; F534-F538 HydrophobicContact CE2-CD2 3.86Å; F534-F538 HydrophobicContact CE2-CE2 4.39Å; F534-F538 AromaticContact CE2-CG 3.94Å; F534-F538 HydrophobicContact CE2-CG 3.94Å; F534-F538 HydrophobicContact CG-CD2 4.3Å; F534-F538 WeakPolarHBondContact O-CB 3.32Å; F534-F538 WeakPolarHBondContact O-CD2 3.35Å; F534-F538 PolarHBondContact O-N 2.93Å
535	T	88.6	Confident	84.3	Confident	4 Å²	4	24.6 Å²	24.6	3%	0.025	13%	0.134	C	C	.	.	I	π-helix	trans	-69.7	-41.8	-179.3	57.3	0	0	0	0	112.2	R502 I531 V532 L539 G540	R502-T535 WeakPolarHBondContact CB-OG1 3.4Å; R502-T535 HydrophobicContact CG-CG2 4.15Å; R502-T535 PolarHBondContact N-OG1 3.46Å; I531-T535 WeakPolarHBondContact O-CG2 3.47Å; I531-T535 PolarHBondContact O-N 2.77Å; I531-T535 PolarHBondContact O-OG1 3.4Å; V532-T535 PolarHBondContact O-N 2.9Å; V532-T535 PolarHBondContact O-OG1 2.71Å; T535-L539 HydrophobicContact CG2-CD1 3.78Å; T535-L539 HydrophobicContact CG2-CG 4.48Å; T535-L539 CarbonylContact O-C 3.55Å; T535-L539 WeakPolarHBondContact O-CA 3.47Å; T535-L539 VanDerWaalsContact O-CB 3.29Å; T535-L539 WeakPolarHBondContact O-CB 3.38Å; T535-L539 PolarHBondContact O-N 3.09Å; T535-G540 PolarHBondContact O-N 3.45Å
536	I	82.2	Confident	83.9	Confident	9 Å²	9	26 Å²	26	5%	0.046	14%	0.14	C	C	.	.	I	π-helix	trans	-62.6	-45	176.7	-71.9	175.7	0	0	0	111.8	V166 F439 V532 G540	V166-I536 HydrophobicContact CG2-CG2 3.69Å; F439-I536 HydrophobicContact CD1-CD1 4.43Å; F439-I536 HydrophobicContact CE1-CD1 3.91Å; V532-I536 HydrophobicContact CG1-CD1 3.61Å; V532-I536 HydrophobicContact CG1-CG1 4.41Å; V532-I536 WeakPolarHBondContact O-CB 3.41Å; V532-I536 WeakPolarHBondContact O-CG1 3.29Å; V532-I536 PolarHBondContact O-N 2.87Å; I536-G540 VanDerWaalsContact O-CA 3.31Å; I536-G540 WeakPolarHBondContact O-CA 3.32Å; I536-G540 PolarHBondContact O-N 2.78Å
537	L	82.4	Confident	83.3	Confident	69 Å²	69	26.3 Å²	26.3	36%	0.361	14%	0.141	S	C	.	.	I	π-helix	trans	-76.1	-54.7	-179.2	-64.3	-175.4	0	0	0	112.7	V166 L533 G541	V166-L537 HydrophobicContact CB-CD2 4.48Å; V166-L537 HydrophobicContact CG1-CD2 3.62Å; V166-L537 HydrophobicContact CG2-CD2 4.32Å; L533-L537 HydrophobicContact CD1-CD1 3.75Å; L533-L537 HydrophobicContact CD1-CG 3.96Å; L533-L537 HydrophobicContact CD2-CD1 4.41Å; L533-L537 HydrophobicContact CG-CD1 3.79Å; L533-L537 HydrophobicContact CG-CG 4.21Å; L533-L537 VanDerWaalsContact O-CB 3.3Å; L533-L537 WeakPolarHBondContact O-CB 3.42Å; L533-L537 VanDerWaalsContact O-CG 3.28Å; L533-L537 WeakPolarHBondContact O-CG 3.48Å; L533-L537 PolarHBondContact O-N 3.31Å; L537-G541 WeakPolarHBondContact O-CA 3.5Å; L537-G541 PolarHBondContact O-N 3Å; L537-G541 VanDerWaalsContact O-N 3.14Å
538	F	84.9	Confident	82.5	Confident	138 Å²	138	33.7 Å²	33.7	61%	0.605	17%	0.169	S	C	*	.	I	π-helix	trans	-83.1	-46.1	-170.9	-68.4	-95.4	0	0	0	112.9	F534 G542	F534-F538 HydrophobicContact CD2-CB 4.37Å; F534-F538 AromaticContact CD2-CD2 3.48Å; F534-F538 HydrophobicContact CD2-CD2 3.48Å; F534-F538 VanDerWaalsContact CD2-CD2 3.48Å; F534-F538 AromaticContact CD2-CE2 3.94Å; F534-F538 HydrophobicContact CD2-CE2 3.94Å; F534-F538 HydrophobicContact CD2-CG 4.03Å; F534-F538 HydrophobicContact CE2-CB 4.15Å; F534-F538 AromaticContact CE2-CD2 3.86Å; F534-F538 HydrophobicContact CE2-CD2 3.86Å; F534-F538 HydrophobicContact CE2-CE2 4.39Å; F534-F538 AromaticContact CE2-CG 3.94Å; F534-F538 HydrophobicContact CE2-CG 3.94Å; F534-F538 HydrophobicContact CG-CD2 4.3Å; F534-F538 WeakPolarHBondContact O-CB 3.32Å; F534-F538 WeakPolarHBondContact O-CD2 3.35Å; F534-F538 PolarHBondContact O-N 2.93Å; F538-G542 WeakPolarHBondContact O-CA 3.45Å; F538-G542 PolarHBondContact O-N 3.24Å
539	L	83.5	Confident	81.8	Confident	19 Å²	19	39.2 Å²	39.2	10%	0.099	20%	0.197	C	C	.	.	I	π-helix	trans	-79.4	-43.9	177.6	-53.6	-178.5	0	0	0	110.7	L466 F498 L501 T535 G542 T543	L466-L539 HydrophobicContact CD2-CD1 4.11Å; F498-L539 HydrophobicContact CD2-CD2 4.26Å; F498-L539 HydrophobicContact CE1-CB 4.32Å; F498-L539 HydrophobicContact CE1-CD2 4.38Å; F498-L539 WeakPolarHBondContact CE1-O 3.31Å; F498-L539 HydrophobicContact CE2-CD2 3.78Å; F498-L539 HydrophobicContact CZ-CD2 3.86Å; L501-L539 HydrophobicContact CD2-CB 3.56Å; T535-L539 HydrophobicContact CG2-CD1 3.78Å; T535-L539 HydrophobicContact CG2-CG 4.48Å; T535-L539 CarbonylContact O-C 3.55Å; T535-L539 WeakPolarHBondContact O-CA 3.47Å; T535-L539 VanDerWaalsContact O-CB 3.29Å; T535-L539 WeakPolarHBondContact O-CB 3.38Å; T535-L539 PolarHBondContact O-N 3.09Å; L539-G542 CarbonylContact O-C 3.59Å; L539-G542 PolarHBondContact O-N 3.23Å; L539-T543 WeakPolarHBondContact O-CB 3.45Å; L539-T543 PolarHBondContact O-N 2.95Å; L539-T543 PolarHBondContact O-OG1 3.3Å
540	G	78.8	Confident	80.9	Confident	1 Å²	1	40.4 Å²	40.4	1%	0.01	20%	0.203	C	C	.	.	I	π-helix	trans	-61.3	-52.8	177.6	0	0	0	0	0	112.1	T535 I536 G542 T543	T535-G540 PolarHBondContact O-N 3.45Å; I536-G540 VanDerWaalsContact O-CA 3.31Å; I536-G540 WeakPolarHBondContact O-CA 3.32Å; I536-G540 PolarHBondContact O-N 2.78Å; G540-G542 VanDerWaalsContact C-N 3.33Å; G540-G542 PolarHBondContact O-N 3.15Å; G540-T543 PolarHBondContact O-N 2.62Å
541	G	77.3	Confident	79.7	Confident	17 Å²	17	41.8 Å²	41.8	18%	0.175	21%	0.211	C	C	.	.	H	α-helix	trans	-63.2	-35.5	172.9	0	0	0	0	0	113.5	L537 T543 P545	L537-G541 WeakPolarHBondContact O-CA 3.5Å; L537-G541 PolarHBondContact O-N 3Å; L537-G541 VanDerWaalsContact O-N 3.14Å; G541-T543 VanDerWaalsContact C-N 3.33Å; G541-T543 PolarHBondContact O-N 3.05Å; G541-P545 VanDerWaalsContact O-CD 3.24Å; G541-P545 WeakPolarHBondContact O-CD 3.49Å
542	G	79.6	Confident	78	Confident	19 Å²	19	46.3 Å²	46.3	20%	0.196	23%	0.234	C	C	.	.	H	α-helix	trans	-72.6	-17.8	177.1	0	0	0	0	0	115.1	F538 L539 G540 P545 L546	F538-G542 WeakPolarHBondContact O-CA 3.45Å; F538-G542 PolarHBondContact O-N 3.24Å; L539-G542 CarbonylContact O-C 3.59Å; L539-G542 PolarHBondContact O-N 3.23Å; G540-G542 VanDerWaalsContact C-N 3.33Å; G540-G542 PolarHBondContact O-N 3.15Å; G542-P545 VanDerWaalsContact O-CD 3.3Å; G542-P545 WeakPolarHBondContact O-CD 3.2Å; G542-P545 WeakPolarHBondContact O-CG 3.46Å; G542-L546 VanDerWaalsContact O-CB 3.26Å; G542-L546 WeakPolarHBondContact O-CB 3.04Å; G542-L546 PolarHBondContact O-N 3.25Å
543	T	77.8	Confident	76.2	Confident	2 Å²	2	52.4 Å²	52.4	1%	0.012	26%	0.263	C	S	.	.	H	α-helix	trans	-69	-39	-174.2	-69.5	0	0	0	0	111.8	I283 L539 G540 G541 L546 I547	I283-T543 HydrophobicContact CB-CG2 4.43Å; I283-T543 HydrophobicContact CD1-CG2 3.83Å; I283-T543 HydrophobicContact CG2-CG2 4.19Å; L539-T543 WeakPolarHBondContact O-CB 3.45Å; L539-T543 PolarHBondContact O-N 2.95Å; L539-T543 PolarHBondContact O-OG1 3.3Å; G540-T543 PolarHBondContact O-N 2.62Å; G541-T543 VanDerWaalsContact C-N 3.33Å; G541-T543 PolarHBondContact O-N 3.05Å; T543-L546 PolarHBondContact O-N 3.22Å; T543-I547 HydrophobicContact CG2-CD1 3.54Å; T543-I547 HydrophobicContact CG2-CG1 4.29Å; T543-I547 VanDerWaalsContact O-CG1 3.32Å; T543-I547 WeakPolarHBondContact O-CG1 3.19Å; T543-I547 PolarHBondContact O-N 3.23Å
544	M	73	Confident	74.4	Confident	28 Å²	28	54.9 Å²	54.9	14%	0.138	27%	0.273	C	S	.	.	H	α-helix	trans	-63.6	-51.3	177.5	-166.2	-151.6	-158.3	0	0	113.3	H160 I283 R548 V565 L567	H160-M544 WeakPolarHBondContact O-CE 3.45Å; I283-M544 HydrophobicContact CD1-CB 4.41Å; I283-M544 HydrophobicContact CG2-CB 4.19Å; I283-M544 HydrophobicContact CG2-CG 4.4Å; M544-R548 WeakPolarHBondContact O-CB 3.42Å; M544-R548 PolarHBondContact O-N 3.14Å; M544-R548 VanDerWaalsContact O-N 3.15Å; M544-V565 HydrophobicContact CE-CB 4.44Å; M544-V565 HydrophobicContact CE-CG1 3.67Å; M544-L567 HydrophobicContact CE-CD1 4.02Å; M544-L567 HydrophobicContact CE-CD2 4.13Å; M544-L567 HydrophobicContact CE-CG 4.09Å; M544-L567 HydrophobicContact SD-CD1 4Å
545	P	78.4	Confident	72.2	Confident	53 Å²	53	54.7 Å²	54.7	34%	0.344	28%	0.279	S	S	.	.	H	α-helix	trans	-66.9	-34.7	175.1	24.7	-32.6	0	0	0	112.8	G541 G542 R548 I549	G541-P545 VanDerWaalsContact O-CD 3.24Å; G541-P545 WeakPolarHBondContact O-CD 3.49Å; G542-P545 VanDerWaalsContact O-CD 3.3Å; G542-P545 WeakPolarHBondContact O-CD 3.2Å; G542-P545 WeakPolarHBondContact O-CG 3.46Å; P545-R548 PolarHBondContact O-N 3.35Å; P545-I549 VanDerWaalsContact O-CG1 3.31Å; P545-I549 WeakPolarHBondContact O-CG1 3.3Å; P545-I549 PolarHBondContact O-N 3.16Å
546	L	77.4	Confident	70.2	Confident	36 Å²	36	63.1 Å²	63.1	19%	0.188	32%	0.318	C	S	.	.	H	α-helix	trans	-60.7	-54.6	177	174.9	64.1	0	0	0	111.8	F494 F498 G542 T543 R548 I549 M550	F494-L546 HydrophobicContact CD1-CD2 4.4Å; F494-L546 HydrophobicContact CE1-CD1 4.04Å; F494-L546 HydrophobicContact CE1-CD2 3.92Å; F498-L546 HydrophobicContact CB-CD2 3.81Å; F498-L546 HydrophobicContact CD1-CD2 3.39Å; F498-L546 HydrophobicContact CD2-CD2 3.73Å; F498-L546 HydrophobicContact CE1-CB 4.48Å; F498-L546 HydrophobicContact CE1-CD2 3.8Å; F498-L546 HydrophobicContact CE2-CD2 4.11Å; F498-L546 HydrophobicContact CG-CD2 3.34Å; F498-L546 HydrophobicContact CZ-CD2 4.14Å; G542-L546 VanDerWaalsContact O-CB 3.26Å; G542-L546 WeakPolarHBondContact O-CB 3.04Å; G542-L546 PolarHBondContact O-N 3.25Å; T543-L546 PolarHBondContact O-N 3.22Å; L546-R548 PolarHBondContact O-N 3.38Å; L546-I549 WeakPolarHBondContact O-CB 3.25Å; L546-I549 PolarHBondContact O-N 3.44Å; L546-M550 HydrophobicContact CD1-CG 4.44Å; L546-M550 HydrophobicContact CD1-SD 4.16Å; L546-M550 HydrophobicContact CG-SD 4.17Å; L546-M550 WeakPolarHBondContact O-CG 3.4Å; L546-M550 PolarHBondContact O-N 3.33Å; L546-M550 VanDerWaalsContact O-N 3.08Å
547	I	72.7	Confident	68.4	Low	9 Å²	9	66.7 Å²	66.7	5%	0.046	34%	0.344	C	S	.	.	H	α-helix	trans	-62.6	-37	-179.2	-60.4	162.4	0	0	0	109.6	I283 F284 L287 V289 T543 I549 M550 D551	I283-I547 HydrophobicContact CG2-CD1 3.85Å; F284-I547 HydrophobicContact CD1-CD1 3.69Å; F284-I547 HydrophobicContact CE1-CD1 3.71Å; L287-I547 HydrophobicContact CB-CG2 4.4Å; L287-I547 HydrophobicContact CD1-CB 3.63Å; L287-I547 HydrophobicContact CD1-CD1 4.19Å; L287-I547 HydrophobicContact CD1-CG2 3.49Å; L287-I547 VanDerWaalsContact CD1-CG2 3.49Å; V289-I547 HydrophobicContact CG2-CG2 4.29Å; T543-I547 HydrophobicContact CG2-CD1 3.54Å; T543-I547 HydrophobicContact CG2-CG1 4.29Å; T543-I547 VanDerWaalsContact O-CG1 3.32Å; T543-I547 WeakPolarHBondContact O-CG1 3.19Å; T543-I547 PolarHBondContact O-N 3.23Å; I547-I549 VanDerWaalsContact C-N 3.31Å; I547-I549 PolarHBondContact O-N 3.33Å; I547-M550 CarbonylContact O-C 3.45Å; I547-M550 PolarHBondContact O-N 3.29Å; I547-M550 VanDerWaalsContact O-N 3.13Å; I547-D551 VanDerWaalsContact O-CB 3.26Å; I547-D551 WeakPolarHBondContact O-CB 3.42Å; I547-D551 PolarHBondContact O-N 2.71Å
548	R	72.6	Confident	66.4	Low	157 Å²	157	72.1 Å²	72.1	59%	0.592	36%	0.36	S	S	*	.	H	α-helix	trans	-62.3	-34.3	175.3	-172.5	173.1	177.9	-179.8	-3.4	113.3	M544 P545 L546 I552	M544-R548 WeakPolarHBondContact O-CB 3.42Å; M544-R548 PolarHBondContact O-N 3.14Å; M544-R548 VanDerWaalsContact O-N 3.15Å; P545-R548 PolarHBondContact O-N 3.35Å; L546-R548 PolarHBondContact O-N 3.38Å; R548-I552 HydrophobicContact CG-CD1 4.29Å; R548-I552 WeakPolarHBondContact O-CB 3.27Å; R548-I552 WeakPolarHBondContact O-CD1 3.31Å; R548-I552 WeakPolarHBondContact O-CG1 3.23Å; R548-I552 PolarHBondContact O-N 3.05Å
549	I	75.8	Confident	64.2	Low	115 Å²	115	77.1 Å²	77.1	59%	0.59	37%	0.374	S	S	*	.	H	α-helix	trans	-67.8	-42.1	172.8	-69.4	161.1	0	0	0	110.5	P545 L546 I547 I552	P545-I549 VanDerWaalsContact O-CG1 3.31Å; P545-I549 WeakPolarHBondContact O-CG1 3.3Å; P545-I549 PolarHBondContact O-N 3.16Å; L546-I549 WeakPolarHBondContact O-CB 3.25Å; L546-I549 PolarHBondContact O-N 3.44Å; I547-I549 VanDerWaalsContact C-N 3.31Å; I547-I549 PolarHBondContact O-N 3.33Å; I549-I552 PolarHBondContact O-N 2.92Å
550	M	69.1	Low	62.1	Low	31 Å²	31	85.5 Å²	85.5	15%	0.153	41%	0.41	C	S	.	.	H	α-helix	trans	-69.8	-36.4	178.8	-62.5	179.2	69.1	0	0	112.8	K491 F494 I495 L546 I547 E553	K491-M550 HydrophobicContact CB-CE 3.7Å; K491-M550 HydrophobicContact CD-CE 4.43Å; K491-M550 HydrophobicContact CG-CE 4.14Å; F494-M550 HydrophobicContact CD1-SD 4.25Å; I495-M550 HydrophobicContact CD1-CE 3.85Å; I495-M550 HydrophobicContact CD1-SD 4.1Å; I495-M550 HydrophobicContact CG1-CE 3.8Å; I495-M550 HydrophobicContact CG1-SD 3.76Å; L546-M550 HydrophobicContact CD1-CG 4.44Å; L546-M550 HydrophobicContact CD1-SD 4.16Å; L546-M550 HydrophobicContact CG-SD 4.17Å; L546-M550 WeakPolarHBondContact O-CG 3.4Å; L546-M550 PolarHBondContact O-N 3.33Å; L546-M550 VanDerWaalsContact O-N 3.08Å; I547-M550 CarbonylContact O-C 3.45Å; I547-M550 PolarHBondContact O-N 3.29Å; I547-M550 VanDerWaalsContact O-N 3.13Å; M550-E553 VanDerWaalsContact O-CB 3.31Å; M550-E553 WeakPolarHBondContact O-CB 3.48Å; M550-E553 PolarHBondContact O-N 3.49Å
551	D	65.1	Low	59.9	Low	74 Å²	74	92.4 Å²	92.4	40%	0.396	45%	0.447	S	S	.	.	H	α-helix	trans	-72.5	-34.5	175.2	174.3	53.2	0	0	0	112	I547 E553 E554 S555	I547-D551 VanDerWaalsContact O-CB 3.26Å; I547-D551 WeakPolarHBondContact O-CB 3.42Å; I547-D551 PolarHBondContact O-N 2.71Å; D551-E553 PolarHBondContact O-N 3.03Å; D551-E553 VanDerWaalsContact O-N 3.15Å; D551-E554 CarbonylContact O-C 3.51Å; D551-E554 PolarHBondContact O-N 2.75Å; D551-S555 WeakPolarHBondContact O-CB 3.41Å; D551-S555 PolarHBondContact O-N 2.64Å
552	I	54.5	Low	58	Low	96 Å²	96	100.9 Å²	100.9	49%	0.492	48%	0.479	S	S	.	.	H	α-helix	trans	-54.3	-36.5	171.8	-81	163.3	0	0	0	111.3	R548 I549 S555	R548-I552 HydrophobicContact CG-CD1 4.29Å; R548-I552 WeakPolarHBondContact O-CB 3.27Å; R548-I552 WeakPolarHBondContact O-CD1 3.31Å; R548-I552 WeakPolarHBondContact O-CG1 3.23Å; R548-I552 PolarHBondContact O-N 3.05Å; I549-I552 PolarHBondContact O-N 2.92Å; I552-S555 WeakPolarHBondContact CA-OG 3.46Å; I552-S555 PolarHBondContact O-OG 2.89Å
553	E	51.6	Low	56.3	Low	128 Å²	128	108.8 Å²	108.8	60%	0.598	51%	0.508	S	S	*	.	H	α-helix	trans	-67.1	-33.6	175.8	-146.3	-167.8	143.7	0	0	113.3	K491 M550 D551	K491-E553 IonicContact NZ-OE1 3.38Å; K491-E553 PolarHBondContact NZ-OE1 3.3Å; K491-E553 IonicContact NZ-OE2 3.65Å; K491-E553 PolarHBondContact NZ-OE2 3.07Å; M550-E553 VanDerWaalsContact O-CB 3.31Å; M550-E553 WeakPolarHBondContact O-CB 3.48Å; M550-E553 PolarHBondContact O-N 3.49Å; D551-E553 PolarHBondContact O-N 3.03Å; D551-E553 VanDerWaalsContact O-N 3.15Å
554	E	47.7	Very low	54.7	Low	91 Å²	91	115.3 Å²	115.3	43%	0.425	54%	0.542	S	S	.	.	H	α-helix	trans	-88.2	-25	176.4	-169.6	162.8	177.5	0	0	112.7	D551 Q556 S557 R558	D551-E554 CarbonylContact O-C 3.51Å; D551-E554 PolarHBondContact O-N 2.75Å; E554-Q556 PolarHBondContact O-N 3.02Å; E554-S557 WeakPolarHBondContact O-CA 3.39Å; E554-S557 WeakPolarHBondContact O-CB 3.42Å; E554-S557 PolarHBondContact O-N 3.06Å; E554-S557 PolarHBondContact O-OG 3.05Å; E554-R558 PolarHBondContact O-N 2.88Å; E554-R558 IonicContact OE1-CZ 3.26Å; E554-R558 IonicContact OE1-NE 3.32Å; E554-R558 PolarHBondContact OE1-NE 2.98Å; E554-R558 IonicContact OE1-NH2 2.71Å; E554-R558 PolarHBondContact OE1-NH2 2.6Å
555	S	43.3	Very low	53.6	Low	52 Å²	52	116.1 Å²	116.1	36%	0.364	55%	0.549	S	S	.	.	H	α-helix	trans	-63.4	-21.4	179.7	78.5	0	0	0	0	114	D551 I552 S557	D551-S555 WeakPolarHBondContact O-CB 3.41Å; D551-S555 PolarHBondContact O-N 2.64Å; I552-S555 WeakPolarHBondContact CA-OG 3.46Å; I552-S555 PolarHBondContact O-OG 2.89Å; S555-S557 PolarHBondContact O-N 3.34Å
556	Q	46.2	Very low	52.4	Low	181 Å²	181	115.7 Å²	115.7	85%	0.846	54%	0.544	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.2	-26.1	167.1	-71	-88.9	-19.4	0	0	112	E554	E554-Q556 PolarHBondContact O-N 3.02Å
557	S	44.3	Very low	51.2	Low	84 Å²	84	114.6 Å²	114.6	59%	0.587	54%	0.538	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.5	-29.6	-177	75.4	0	0	0	0	114.8	E554 S555	E554-S557 WeakPolarHBondContact O-CA 3.39Å; E554-S557 WeakPolarHBondContact O-CB 3.42Å; E554-S557 PolarHBondContact O-N 3.06Å; E554-S557 PolarHBondContact O-OG 3.05Å; S555-S557 PolarHBondContact O-N 3.34Å
558	R	40.3	Very low	50.1	Low	184 Å²	184	114.8 Å²	114.8	69%	0.694	54%	0.54	S	S	*	.			trans	-128.4	85.9	-175	-60.4	-168	-141.8	-158.5	11.5	113	E554	E554-R558 PolarHBondContact O-N 2.88Å; E554-R558 IonicContact OE1-CZ 3.26Å; E554-R558 IonicContact OE1-NE 3.32Å; E554-R558 PolarHBondContact OE1-NE 2.98Å; E554-R558 IonicContact OE1-NH2 2.71Å; E554-R558 PolarHBondContact OE1-NH2 2.6Å
559	R	39	Very low	49.4	Very low	242 Å²	242	110.6 Å²	110.6	91%	0.913	53%	0.526	S	S	*	.			trans	-101.6	81.2	-177.6	-165.9	178.8	-175	-175.3	2.1	113.1
560	K	38.8	Very low	48.3	Very low	195 Å²	195	107.3 Å²	107.3	85%	0.848	51%	0.512	S	S	*	.			trans	-154.9	149.7	164	-113.5	173.2	-176.1	-179.7	0	112.4
561	N	34.6	Very low	47.6	Very low	146 Å²	146	108.5 Å²	108.5	78%	0.781	52%	0.517	S	S	*	.			trans	57.9	68.8	171.3	-62.8	3.7	0	0	0	117.5	K563	N561-K563 PolarHBondContact O-N 2.94Å
562	K	36.7	Very low	47.1	Very low	196 Å²	196	107.8 Å²	107.8	85%	0.852	51%	0.51	S	S	*	.			trans	-75.2	102.1	160.8	-175.6	-172.6	176.9	-164.8	0	110.1
563	K	43.8	Very low	46.9	Very low	184 Å²	184	105.3 Å²	105.3	80%	0.8	50%	0.497	S	S	*	.			trans	-86.6	162.4	159.4	-71.4	-173.8	176.9	-176.9	0	109.5	N561	N561-K563 PolarHBondContact O-N 2.94Å
564	D	43.2	Very low	46.9	Very low	139 Å²	139	101 Å²	101	74%	0.743	49%	0.487	S	S	*	.			trans	-73.4	141.3	178.8	-70.1	-45	0	0	0	112.8	N566	D564-N566 PolarHBondContact O-N 2.98Å
565	V	51.4	Low	46.8	Very low	46 Å²	46	101 Å²	101	28%	0.279	49%	0.49	S	S	.	.			trans	-88.6	91	-168.6	-179.6	0	0	0	0	110.1	H160 A286 L287 M544 L567	H160-V565 PolarHBondContact ND1-O 3.34Å; A286-V565 HydrophobicContact CB-CG1 3.7Å; L287-V565 HydrophobicContact CD2-CG1 3.95Å; L287-V565 HydrophobicContact CD2-CG2 4.29Å; M544-V565 HydrophobicContact CE-CB 4.44Å; M544-V565 HydrophobicContact CE-CG1 3.67Å; V565-L567 HydrophobicContact CG1-CD2 4.36Å
566	N	52.3	Low	46.9	Very low	43 Å²	43	101.2 Å²	101.2	23%	0.23	49%	0.489	C	S	.	.			trans	-87.5	118.9	177.5	-62.7	-15.9	0	0	0	110.5	H160 A286 D564 K572	H160-N566 PolarHBondContact CE1-OD1 3.48Å; H160-N566 VanDerWaalsContact CE1-OD1 3.31Å; A286-N566 WeakPolarHBondContact CB-O 3.47Å; D564-N566 PolarHBondContact O-N 2.98Å; N566-K572 WeakPolarHBondContact O-CE 3.44Å; N566-K572 PolarHBondContact O-NZ 2.94Å
567	L	52.3	Low	46.7	Very low	13 Å²	13	96 Å²	96	7%	0.068	47%	0.467	C	S	.	.			trans	-91	-11.9	-179.1	-68.4	-169.2	0	0	0	115.1	H160 I283 A286 M544 V565	H160-L567 VanDerWaalsContact O-CD1 3.24Å; H160-L567 WeakPolarHBondContact O-CD1 3.24Å; I283-L567 HydrophobicContact CB-CD2 4.4Å; I283-L567 HydrophobicContact CG1-CD2 3.92Å; A286-L567 HydrophobicContact CB-CD2 3.77Å; M544-L567 HydrophobicContact CE-CD1 4.02Å; M544-L567 HydrophobicContact CE-CD2 4.13Å; M544-L567 HydrophobicContact CE-CG 4.09Å; M544-L567 HydrophobicContact SD-CD1 4Å; V565-L567 HydrophobicContact CG1-CD2 4.36Å
568	S	50.1	Low	46.4	Very low	13 Å²	13	97 Å²	97	9%	0.091	47%	0.465	C	S	.	.			trans	-76.1	129.6	-177.1	168.1	0	0	0	0	111.9	E164 T570 Q571 K572	E164-S568 WeakPolarHBondContact OE1-CA 3.36Å; E164-S568 WeakPolarHBondContact OE1-CB 3.36Å; E164-S568 PolarHBondContact OE1-OG 3.05Å; S568-T570 PolarHBondContact OG-N 2.86Å; S568-Q571 WeakPolarHBondContact OG-CB 3.23Å; S568-Q571 PolarHBondContact OG-N 3.37Å; S568-K572 PolarHBondContact O-N 3.45Å
569	K	56.7	Low	46.7	Very low	69 Å²	69	94.1 Å²	94.1	30%	0.3	47%	0.468	S	S	.	.	H	α-helix	trans	-63.2	-48.8	166.3	-74.2	178.8	164.6	-177.3	0	108.9	E164 V278 E435 Q571 K572 M573	E164-K569 PolarHBondContact OE1-N 3.17Å; E164-K569 VanDerWaalsContact OE2-CB 3.31Å; E164-K569 WeakPolarHBondContact OE2-CB 3.45Å; E164-K569 PolarHBondContact OE2-N 3.46Å; V278-K569 HydrophobicContact CG1-CD 4.49Å; E435-K569 IonicContact OE1-NZ 3.23Å; E435-K569 PolarHBondContact OE1-NZ 2.9Å; E435-K569 IonicContact OE2-NZ 3.91Å; E435-K569 PolarHBondContact OE2-NZ 3.23Å; K569-Q571 PolarHBondContact O-N 3.24Å; K569-K572 PolarHBondContact O-N 2.9Å; K569-M573 WeakPolarHBondContact O-CB 3.28Å; K569-M573 PolarHBondContact O-N 3.34Å
570	T	54.1	Low	46.8	Very low	47 Å²	47	90.6 Å²	90.6	29%	0.288	46%	0.462	S	S	.	.	H	α-helix	trans	-63.5	-38.1	-174.1	-49.6	0	0	0	0	112.7	I155 E164 S568 M573 G574	I155-T570 HydrophobicContact CD1-CG2 3.87Å; E164-T570 PolarHBondContact OE1-N 3.19Å; E164-T570 PolarHBondContact OE1-OG1 3.47Å; S568-T570 PolarHBondContact OG-N 2.86Å; T570-M573 WeakPolarHBondContact O-CB 3.4Å; T570-M573 PolarHBondContact O-N 2.89Å; T570-G574 PolarHBondContact O-N 2.97Å; T570-G574 VanDerWaalsContact O-N 3.13Å
571	Q	53.5	Low	46.7	Very low	55 Å²	55	86.1 Å²	86.1	26%	0.257	44%	0.444	S	S	.	.	H	α-helix	trans	-70.5	-40.3	176.8	-165.4	177.1	12.5	0	0	111.8	I155 S568 K569 M573 G574 N575	I155-Q571 HydrophobicContact CG2-CB 3.93Å; I155-Q571 HydrophobicContact CG2-CG 4.03Å; S568-Q571 WeakPolarHBondContact OG-CB 3.23Å; S568-Q571 PolarHBondContact OG-N 3.37Å; K569-Q571 PolarHBondContact O-N 3.24Å; Q571-M573 VanDerWaalsContact C-N 3.3Å; Q571-M573 PolarHBondContact O-N 3.23Å; Q571-G574 PolarHBondContact O-N 3.27Å; Q571-N575 PolarHBondContact O-N 2.91Å; Q571-N575 PolarHBondContact O-OD1 3.3Å; Q571-N575 VanDerWaalsContact O-OD1 3.08Å
572	K	55.6	Low	46.8	Very low	59 Å²	59	80.8 Å²	80.8	26%	0.257	42%	0.416	S	S	.	.	H	α-helix	trans	-62.8	-38.5	171.9	-75.9	-178.2	-178.7	168.5	0	111.6	N285 N566 S568 K569 G574 N575 T576	N285-K572 PolarHBondContact O-NZ 3.41Å; N566-K572 WeakPolarHBondContact O-CE 3.44Å; N566-K572 PolarHBondContact O-NZ 2.94Å; S568-K572 PolarHBondContact O-N 3.45Å; K569-K572 PolarHBondContact O-N 2.9Å; K572-G574 VanDerWaalsContact C-N 3.31Å; K572-G574 PolarHBondContact O-N 3.49Å; K572-N575 CarbonylContact O-C 3.5Å; K572-N575 PolarHBondContact O-N 3.44Å; K572-T576 WeakPolarHBondContact O-CG2 3.43Å; K572-T576 PolarHBondContact O-N 3.45Å; K572-T576 PolarHBondContact O-OG1 3.44Å
573	M	50.2	Low	46.9	Very low	45 Å²	45	74.2 Å²	74.2	22%	0.222	39%	0.394	C	S	.	.	H	α-helix	trans	-57.2	-43	174.9	-177.1	174.6	171.4	0	0	111.7	Q425 R428 K569 T570 Q571 T576 I577	Q425-M573 VanDerWaalsContact OE1-CE 3.26Å; R428-M573 HydrophobicContact CG-CE 4.12Å; R428-M573 HydrophobicContact CG-SD 4.1Å; K569-M573 WeakPolarHBondContact O-CB 3.28Å; K569-M573 PolarHBondContact O-N 3.34Å; T570-M573 WeakPolarHBondContact O-CB 3.4Å; T570-M573 PolarHBondContact O-N 2.89Å; Q571-M573 VanDerWaalsContact C-N 3.3Å; Q571-M573 PolarHBondContact O-N 3.23Å; M573-T576 WeakPolarHBondContact CA-OG1 3.47Å; M573-T576 PolarHBondContact O-N 3.49Å; M573-T576 PolarHBondContact O-OG1 3.34Å; M573-I577 HydrophobicContact CE-CD1 4.23Å; M573-I577 HydrophobicContact CG-CD1 3.93Å; M573-I577 WeakPolarHBondContact O-CD1 3.05Å; M573-I577 VanDerWaalsContact O-CG1 3.25Å; M573-I577 WeakPolarHBondContact O-CG1 3.16Å; M573-I577 PolarHBondContact O-N 2.88Å; M573-I577 VanDerWaalsContact O-N 3.13Å
574	G	51.3	Low	46.4	Very low	38 Å²	38	70.1 Å²	70.1	39%	0.392	38%	0.378	S	S	.	.	H	α-helix	trans	-57.4	-54	171.4	0	0	0	0	0	112.7	T570 Q571 K572 T576 I577 D578	T570-G574 PolarHBondContact O-N 2.97Å; T570-G574 VanDerWaalsContact O-N 3.13Å; Q571-G574 PolarHBondContact O-N 3.27Å; K572-G574 VanDerWaalsContact C-N 3.31Å; K572-G574 PolarHBondContact O-N 3.49Å; G574-T576 PolarHBondContact O-N 2.92Å; G574-T576 VanDerWaalsContact O-N 3.16Å; G574-I577 WeakPolarHBondContact O-CB 3.41Å; G574-I577 PolarHBondContact O-N 3.31Å; G574-D578 PolarHBondContact O-N 3.19Å
575	N	45.5	Very low	46.1	Very low	90 Å²	90	67.6 Å²	67.6	48%	0.481	36%	0.364	S	S	.	.	H	α-helix	trans	-62	-19.5	177.3	-75.7	71	0	0	0	114.8	Q571 K572	Q571-N575 PolarHBondContact O-N 2.91Å; Q571-N575 PolarHBondContact O-OD1 3.3Å; Q571-N575 VanDerWaalsContact O-OD1 3.08Å; K572-N575 CarbonylContact O-C 3.5Å; K572-N575 PolarHBondContact O-N 3.44Å
576	T	44.3	Very low	45.7	Very low	56 Å²	56	68.5 Å²	68.5	34%	0.344	37%	0.37	S	S	.	.	H	α-helix	trans	-91	-9.9	171.8	53.9	0	0	0	0	113.6	K572 M573 G574 L582	K572-T576 WeakPolarHBondContact O-CG2 3.43Å; K572-T576 PolarHBondContact O-N 3.45Å; K572-T576 PolarHBondContact O-OG1 3.44Å; M573-T576 WeakPolarHBondContact CA-OG1 3.47Å; M573-T576 PolarHBondContact O-N 3.49Å; M573-T576 PolarHBondContact O-OG1 3.34Å; G574-T576 PolarHBondContact O-N 2.92Å; G574-T576 VanDerWaalsContact O-N 3.16Å; T576-L582 WeakPolarHBondContact O-CG 3.34Å
577	I	42.2	Very low	45	Very low	73 Å²	73	71.4 Å²	71.4	37%	0.374	38%	0.382	S	S	.	.	H	α-helix	trans	-90.9	-17.3	175.1	-72.8	164.9	0	0	0	111	M573 G574 T579 L582	M573-I577 HydrophobicContact CE-CD1 4.23Å; M573-I577 HydrophobicContact CG-CD1 3.93Å; M573-I577 WeakPolarHBondContact O-CD1 3.05Å; M573-I577 VanDerWaalsContact O-CG1 3.25Å; M573-I577 WeakPolarHBondContact O-CG1 3.16Å; M573-I577 PolarHBondContact O-N 2.88Å; M573-I577 VanDerWaalsContact O-N 3.13Å; G574-I577 WeakPolarHBondContact O-CB 3.41Å; G574-I577 PolarHBondContact O-N 3.31Å; I577-T579 PolarHBondContact O-N 2.97Å; I577-L582 HydrophobicContact CG1-CD1 4.28Å
578	D	39.3	Very low	44.3	Very low	103 Å²	103	76.9 Å²	76.9	55%	0.551	41%	0.407	S	S	*	.	S	Bend	trans	-50.3	122.7	165.8	-71	-39.2	0	0	0	109.9	G574 E580 H581	G574-D578 PolarHBondContact O-N 3.19Å; D578-E580 VanDerWaalsContact C-N 3.26Å; D578-E580 PolarHBondContact O-N 3.45Å; D578-H581 PolarHBondContact O-N 3.46Å
579	T	45.9	Very low	44	Very low	125 Å²	125	79.8 Å²	79.8	77%	0.767	42%	0.419	S	S	*	.	H	α-helix	trans	-68.4	-16.2	-140.7	-30.8	0	0	0	0	116	I577 S583	I577-T579 PolarHBondContact O-N 2.97Å; T579-S583 PolarHBondContact O-OG 2.9Å
580	E	40.8	Very low	43.3	Very low	167 Å²	167	81.4 Å²	81.4	78%	0.78	42%	0.424	S	S	*	.	H	α-helix	trans	-72.4	-43.3	178.9	-68.1	178.4	123.8	0	0	111.9	D578 L582 S583 E584	D578-E580 VanDerWaalsContact C-N 3.26Å; D578-E580 PolarHBondContact O-N 3.45Å; E580-L582 PolarHBondContact O-N 2.85Å; E580-S583 PolarHBondContact O-N 3.08Å; E580-S583 PolarHBondContact O-OG 3.37Å; E580-E584 WeakPolarHBondContact O-CB 3.35Å; E580-E584 PolarHBondContact O-N 3Å
581	H	37.2	Very low	42.6	Very low	101 Å²	101	84.6 Å²	84.6	47%	0.468	44%	0.436	S	S	.	.	H	α-helix	trans	-72.4	-23.9	-172.6	-82.5	-36.3	0	0	0	114.4	D578 E584 L585	D578-H581 PolarHBondContact O-N 3.46Å; H581-E584 IonicContact CE1-OE2 3.26Å; H581-E584 PolarHBondContact CE1-OE2 3.19Å; H581-E584 VanDerWaalsContact CE1-OE2 3.26Å; H581-E584 IonicContact CG-OE2 2.78Å; H581-E584 IonicContact ND1-OE2 2.75Å; H581-E584 PolarHBondContact ND1-OE2 2.86Å; H581-L585 WeakPolarHBondContact O-CB 3.48Å; H581-L585 WeakPolarHBondContact O-CG 3.39Å; H581-L585 PolarHBondContact O-N 3.06Å
582	L	36.4	Very low	42.3	Very low	35 Å²	35	84.1 Å²	84.1	18%	0.183	44%	0.441	C	S	.	.	H	α-helix	trans	-71.4	-39.7	173.1	-86.6	169.2	0	0	0	112	T576 I577 E580 T586	T576-L582 WeakPolarHBondContact O-CG 3.34Å; I577-L582 HydrophobicContact CG1-CD1 4.28Å; E580-L582 PolarHBondContact O-N 2.85Å; L582-T586 PolarHBondContact O-N 2.94Å; L582-T586 PolarHBondContact O-OG1 2.79Å
583	S	37.9	Very low	41.7	Very low	58 Å²	58	84.4 Å²	84.4	41%	0.406	44%	0.443	S	S	.	.	H	α-helix	trans	-63.8	-46.7	169.3	26.6	0	0	0	0	111.3	T579 E580 L585 T586 E587	T579-S583 PolarHBondContact O-OG 2.9Å; E580-S583 PolarHBondContact O-N 3.08Å; E580-S583 PolarHBondContact O-OG 3.37Å; S583-L585 PolarHBondContact O-N 3.45Å; S583-T586 PolarHBondContact O-N 3.03Å; S583-T586 VanDerWaalsContact O-N 3.07Å; S583-T586 PolarHBondContact O-OG1 3.29Å; S583-E587 PolarHBondContact O-N 3.27Å
584	E	35	Very low	41.5	Very low	97 Å²	97	87.1 Å²	87.1	45%	0.453	46%	0.458	S	S	.	.	H	α-helix	trans	-61.6	-42.4	-178.2	-157.4	171.6	-134.9	0	0	111.8	E580 H581 T586 E587 E588	E580-E584 WeakPolarHBondContact O-CB 3.35Å; E580-E584 PolarHBondContact O-N 3Å; H581-E584 IonicContact CE1-OE2 3.26Å; H581-E584 PolarHBondContact CE1-OE2 3.19Å; H581-E584 VanDerWaalsContact CE1-OE2 3.26Å; H581-E584 IonicContact CG-OE2 2.78Å; H581-E584 IonicContact ND1-OE2 2.75Å; H581-E584 PolarHBondContact ND1-OE2 2.86Å; E584-T586 VanDerWaalsContact C-N 3.33Å; E584-T586 PolarHBondContact O-N 2.67Å; E584-E587 PolarHBondContact O-N 3.03Å; E584-E588 WeakPolarHBondContact O-CB 3.29Å; E584-E588 WeakPolarHBondContact O-CG 3.35Å; E584-E588 PolarHBondContact O-N 3.23Å
585	L	36.3	Very low	41.1	Very low	87 Å²	87	93.2 Å²	93.2	46%	0.455	47%	0.47	S	S	.	.	H	α-helix	trans	-59.9	-39.5	172.2	-85.4	162.8	0	0	0	113	H581 S583 E589	H581-L585 WeakPolarHBondContact O-CB 3.48Å; H581-L585 WeakPolarHBondContact O-CG 3.39Å; H581-L585 PolarHBondContact O-N 3.06Å; S583-L585 PolarHBondContact O-N 3.45Å; L585-E589 PolarHBondContact O-N 2.93Å; L585-E589 VanDerWaalsContact O-N 3.09Å
586	T	42.3	Very low	41.2	Very low	65 Å²	65	92.3 Å²	92.3	40%	0.399	46%	0.463	S	S	.	.	H	α-helix	trans	-73.2	-30.9	176.4	56	0	0	0	0	113.5	L582 S583 E584 Y590	L582-T586 PolarHBondContact O-N 2.94Å; L582-T586 PolarHBondContact O-OG1 2.79Å; S583-T586 PolarHBondContact O-N 3.03Å; S583-T586 VanDerWaalsContact O-N 3.07Å; S583-T586 PolarHBondContact O-OG1 3.29Å; E584-T586 VanDerWaalsContact C-N 3.33Å; E584-T586 PolarHBondContact O-N 2.67Å; T586-Y590 VanDerWaalsContact O-CB 3.24Å; T586-Y590 WeakPolarHBondContact O-CB 3.42Å; T586-Y590 PolarHBondContact O-N 2.91Å
587	E	37.3	Very low	41.4	Very low	104 Å²	104	97.5 Å²	97.5	49%	0.486	48%	0.476	S	S	.	.	H	α-helix	trans	-81.1	-36.1	176.4	-68.6	-170.4	149	0	0	111.3	S583 E584 Y590 E591 R628	S583-E587 PolarHBondContact O-N 3.27Å; E584-E587 PolarHBondContact O-N 3.03Å; E587-Y590 PolarHBondContact O-N 3.27Å; E587-E591 WeakPolarHBondContact O-CG 3.45Å; E587-E591 PolarHBondContact O-N 3.4Å; E587-R628 IonicContact OE1-NH2 3.42Å; E587-R628 PolarHBondContact OE1-NH2 2.88Å
588	E	38.3	Very low	41.6	Very low	128 Å²	128	102.8 Å²	102.8	60%	0.598	50%	0.5	S	S	*	.	H	α-helix	trans	-65.9	-46.1	172.8	-77	-161.2	147.3	0	0	113.1	E584 Y590 A592	E584-E588 WeakPolarHBondContact O-CB 3.29Å; E584-E588 WeakPolarHBondContact O-CG 3.35Å; E584-E588 PolarHBondContact O-N 3.23Å; E588-Y590 PolarHBondContact O-N 3.21Å; E588-A592 WeakPolarHBondContact O-CB 3.34Å; E588-A592 PolarHBondContact O-N 2.72Å
589	E	43.3	Very low	42	Very low	73 Å²	73	103.5 Å²	103.5	34%	0.341	50%	0.504	S	S	.	.	H	α-helix	trans	-60.5	-34	174.5	-81.5	-149.1	139	0	0	111.5	K219 L585 Q593	K219-E589 IonicContact NZ-OE1 3.7Å; K219-E589 IonicContact NZ-OE2 2.75Å; K219-E589 PolarHBondContact NZ-OE2 3.01Å; L585-E589 PolarHBondContact O-N 2.93Å; L585-E589 VanDerWaalsContact O-N 3.09Å; E589-Q593 PolarHBondContact O-N 3.22Å
590	Y	43	Very low	42.5	Very low	103 Å²	103	99.2 Å²	99.2	40%	0.404	48%	0.476	S	S	.	.	H	α-helix	trans	-78.1	-44.7	-177.3	-165.4	-98.2	0	0	0	112.5	T586 E587 E588 Q593 I594	T586-Y590 VanDerWaalsContact O-CB 3.24Å; T586-Y590 WeakPolarHBondContact O-CB 3.42Å; T586-Y590 PolarHBondContact O-N 2.91Å; E587-Y590 PolarHBondContact O-N 3.27Å; E588-Y590 PolarHBondContact O-N 3.21Å; Y590-Q593 PolarHBondContact O-N 2.88Å; Y590-I594 HydrophobicContact CD1-CD1 4.14Å; Y590-I594 HydrophobicContact CE1-CD1 4Å; Y590-I594 PolarHBondContact O-N 3.11Å
591	E	39.2	Very low	43.2	Very low	114 Å²	114	98.6 Å²	98.6	53%	0.533	47%	0.47	S	S	.	.	H	α-helix	trans	-66.6	-38.5	172.6	-69.8	-143.2	159	0	0	111.6	E587 Q593 I594 Y595	E587-E591 WeakPolarHBondContact O-CG 3.45Å; E587-E591 PolarHBondContact O-N 3.4Å; E591-Q593 VanDerWaalsContact C-N 3.3Å; E591-Q593 PolarHBondContact O-N 2.88Å; E591-I594 WeakPolarHBondContact O-CA 3.38Å; E591-I594 PolarHBondContact O-N 3.19Å; E591-Y595 HydrophobicContact CB-CD2 4.38Å; E591-Y595 WeakPolarHBondContact O-CD2 3.46Å; E591-Y595 PolarHBondContact O-N 3.05Å
592	A	46.6	Very low	44.7	Very low	45 Å²	45	96.7 Å²	96.7	37%	0.372	48%	0.478	S	S	.	.	H	α-helix	trans	-59.1	-39.6	174.7	0	0	0	0	0	112.2	E588 I594 Y595 Q596	E588-A592 WeakPolarHBondContact O-CB 3.34Å; E588-A592 PolarHBondContact O-N 2.72Å; A592-I594 VanDerWaalsContact C-N 3.3Å; A592-I594 PolarHBondContact O-N 3.07Å; A592-Y595 PolarHBondContact O-N 3.19Å; A592-Q596 VanDerWaalsContact O-CB 3.25Å; A592-Q596 WeakPolarHBondContact O-CB 3.49Å; A592-Q596 WeakPolarHBondContact O-CG 3.35Å; A592-Q596 PolarHBondContact O-N 3.35Å
593	Q	44.4	Very low	45.9	Very low	65 Å²	65	101 Å²	101	30%	0.304	50%	0.495	S	S	.	.	H	α-helix	trans	-64.7	-31.1	173.1	-85.9	-173.9	-3.9	0	0	113.4	H413 E589 Y590 E591	H413-Q593 PolarHBondContact NE2-NE2 3.31Å; E589-Q593 PolarHBondContact O-N 3.22Å; Y590-Q593 PolarHBondContact O-N 2.88Å; E591-Q593 VanDerWaalsContact C-N 3.3Å; E591-Q593 PolarHBondContact O-N 2.88Å
594	I	45.1	Very low	47.1	Very low	102 Å²	102	100.5 Å²	100.5	52%	0.523	49%	0.487	S	S	.	.	H	α-helix	trans	-75	-46.4	176.6	-67.5	171.5	0	0	0	110.6	Y590 E591 A592	Y590-I594 HydrophobicContact CD1-CD1 4.14Å; Y590-I594 HydrophobicContact CE1-CD1 4Å; Y590-I594 PolarHBondContact O-N 3.11Å; E591-I594 WeakPolarHBondContact O-CA 3.38Å; E591-I594 PolarHBondContact O-N 3.19Å; A592-I594 VanDerWaalsContact C-N 3.3Å; A592-I594 PolarHBondContact O-N 3.07Å
595	Y	43.2	Very low	48.5	Very low	166 Å²	166	102.1 Å²	102.1	65%	0.651	49%	0.489	S	S	*	.	H	α-helix	trans	-76.2	-35.6	-177.6	-78	-73.6	0	0	0	114.1	E591 A592 R597	E591-Y595 HydrophobicContact CB-CD2 4.38Å; E591-Y595 WeakPolarHBondContact O-CD2 3.46Å; E591-Y595 PolarHBondContact O-N 3.05Å; A592-Y595 PolarHBondContact O-N 3.19Å; Y595-R597 PolarHBondContact O-N 3.26Å
596	Q	47	Very low	49.9	Very low	72 Å²	72	101.9 Å²	101.9	34%	0.336	49%	0.488	S	S	.	.	G	3₁₀ helix	trans	-61.1	-20	179.8	-83.8	-166.5	-12.8	0	0	113.9	A592 Q598 D599 L600	A592-Q596 VanDerWaalsContact O-CB 3.25Å; A592-Q596 WeakPolarHBondContact O-CB 3.49Å; A592-Q596 WeakPolarHBondContact O-CG 3.35Å; A592-Q596 PolarHBondContact O-N 3.35Å; Q596-Q598 PolarHBondContact O-N 3.05Å; Q596-D599 PolarHBondContact O-N 3.19Å; Q596-L600 HydrophobicContact CB-CD2 4.35Å; Q596-L600 WeakPolarHBondContact O-CG 3.35Å
597	R	48.9	Very low	51.2	Low	164 Å²	164	99.4 Å²	99.4	62%	0.619	47%	0.472	S	S	*	.	G	3₁₀ helix	trans	-55.7	-15.7	-177.2	-94.8	-176.3	157.7	172.9	-2	115.8	Y595 L600 A608	Y595-R597 PolarHBondContact O-N 3.26Å; R597-L600 HydrophobicContact CG-CD1 4.49Å; R597-A608 PolarHBondContact NH2-O 3.05Å
598	Q	45.2	Very low	52.4	Low	185 Å²	185	95.1 Å²	95.1	86%	0.864	46%	0.455	S	S	*	.	G	3₁₀ helix	trans	-83	-18.8	-176.6	-65.6	-171.2	-12.2	0	0	115.2	Q596	Q596-Q598 PolarHBondContact O-N 3.05Å
599	D	49.4	Very low	53.6	Low	118 Å²	118	93.9 Å²	93.9	63%	0.631	45%	0.447	S	S	*	.	S	Bend	trans	-133.6	22.8	-176.1	-154	4.5	0	0	0	114.4	Q596 K601	Q596-D599 PolarHBondContact O-N 3.19Å; D599-K601 PolarHBondContact O-N 2.9Å; D599-K601 VanDerWaalsContact OD1-CE 3.32Å; D599-K601 WeakPolarHBondContact OD1-CE 3.49Å; D599-K601 IonicContact OD1-NZ 3.45Å; D599-K601 PolarHBondContact OD1-NZ 3.25Å; D599-K601 IonicContact OD2-NZ 3.95Å
600	L	54.8	Low	54.6	Low	35 Å²	35	96.6 Å²	96.6	18%	0.183	46%	0.455	C	S	.	.			trans	-71.1	125.7	177.3	-60.4	179	0	0	0	111.9	Q596 R597 M604 W605 A608	Q596-L600 HydrophobicContact CB-CD2 4.35Å; Q596-L600 WeakPolarHBondContact O-CG 3.35Å; R597-L600 HydrophobicContact CG-CD1 4.49Å; L600-M604 HydrophobicContact CB-CB 4.39Å; L600-M604 HydrophobicContact CD2-CB 4.1Å; L600-M604 HydrophobicContact CD2-CE 4.05Å; L600-W605 HydrophobicContact CB-CB 4.37Å; L600-A608 HydrophobicContact CD1-CB 3.56Å
601	K	57.2	Low	55.9	Low	154 Å²	154	94 Å²	94	67%	0.67	45%	0.448	S	S	*	.			trans	-117.8	152.2	177	-68.8	165.2	-171.3	132.6	0	111	D599	D599-K601 PolarHBondContact O-N 2.9Å; D599-K601 VanDerWaalsContact OD1-CE 3.32Å; D599-K601 WeakPolarHBondContact OD1-CE 3.49Å; D599-K601 IonicContact OD1-NZ 3.45Å; D599-K601 PolarHBondContact OD1-NZ 3.25Å; D599-K601 IonicContact OD2-NZ 3.95Å
602	G	67.9	Low	57.3	Low	60 Å²	60	90 Å²	90	62%	0.619	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.4	-134.5	174.9	0	0	0	0	0	114.2	M604 W605 L606	G602-M604 VanDerWaalsContact C-N 3.31Å; G602-M604 PolarHBondContact O-N 2.88Å; G602-W605 WeakPolarHBondContact O-CB 3.44Å; G602-W605 PolarHBondContact O-N 2.67Å; G602-W605 VanDerWaalsContact O-N 3.15Å; G602-L606 PolarHBondContact O-N 2.94Å
603	F	61.8	Low	57.9	Low	127 Å²	127	90 Å²	90	56%	0.557	43%	0.426	S	S	*	.	H	α-helix	trans	-55.9	-41.3	-175.1	178.5	-99.2	0	0	0	113.1	W605 L606 D607 L611	F603-W605 PolarHBondContact O-N 2.88Å; F603-L606 PolarHBondContact O-N 3.33Å; F603-L606 VanDerWaalsContact O-N 3.07Å; F603-D607 HydrophobicContact CE1-CB 4.3Å; F603-D607 WeakPolarHBondContact O-CB 3.43Å; F603-D607 PolarHBondContact O-N 2.6Å; F603-L611 HydrophobicContact CE2-CD1 4.07Å; F603-L611 HydrophobicContact CZ-CD1 4.03Å
604	M	61.9	Low	59.2	Low	46 Å²	46	92.6 Å²	92.6	23%	0.227	44%	0.437	C	S	.	.	H	α-helix	trans	-62.5	-28.9	-178.5	-59.6	177.7	77.2	0	0	112.8	F223 L600 G602 A608	F223-M604 HydrophobicContact CB-CE 4.5Å; L600-M604 HydrophobicContact CB-CB 4.39Å; L600-M604 HydrophobicContact CD2-CB 4.1Å; L600-M604 HydrophobicContact CD2-CE 4.05Å; G602-M604 VanDerWaalsContact C-N 3.31Å; G602-M604 PolarHBondContact O-N 2.88Å; M604-A608 WeakPolarHBondContact O-CB 3.46Å; M604-A608 PolarHBondContact O-N 2.99Å
605	W	65.1	Low	60.4	Low	132 Å²	132	88.8 Å²	88.8	50%	0.5	42%	0.417	S	S	.	.	H	α-helix	trans	-72.1	-43.3	173.2	177.7	94.2	0	0	0	112	L600 G602 F603 D607 K609 Y610	L600-W605 HydrophobicContact CB-CB 4.37Å; G602-W605 WeakPolarHBondContact O-CB 3.44Å; G602-W605 PolarHBondContact O-N 2.67Å; G602-W605 VanDerWaalsContact O-N 3.15Å; F603-W605 PolarHBondContact O-N 2.88Å; W605-D607 VanDerWaalsContact C-N 3.32Å; W605-K609 HydrophobicContact CD2-CD 4.47Å; W605-K609 HydrophobicContact CH2-CD 3.81Å; W605-K609 HydrophobicContact CZ2-CD 3.57Å; W605-K609 HydrophobicContact CZ3-CD 4.32Å; W605-K609 WeakPolarHBondContact O-CB 3.37Å; W605-K609 PolarHBondContact O-N 3.04Å; W605-K609 VanDerWaalsContact O-N 3.11Å; W605-Y610 HydrophobicContact CH2-CE2 4.45Å; W605-Y610 HydrophobicContact CZ3-CE2 4.26Å
606	L	65.4	Low	61.3	Low	81 Å²	81	81.5 Å²	81.5	42%	0.424	39%	0.389	S	S	.	.	H	α-helix	trans	-64.9	-40.6	178.2	-178.1	148.7	0	0	0	110.6	G602 F603 Y610 L611	G602-L606 PolarHBondContact O-N 2.94Å; F603-L606 PolarHBondContact O-N 3.33Å; F603-L606 VanDerWaalsContact O-N 3.07Å; L606-Y610 HydrophobicContact CG-CD2 4.49Å; L606-Y610 WeakPolarHBondContact O-CB 3.47Å; L606-Y610 PolarHBondContact O-N 3.24Å; L606-L611 HydrophobicContact CD2-CD1 3.82Å; L606-L611 HydrophobicContact CD2-CD2 4.46Å; L606-L611 HydrophobicContact CD2-CG 3.91Å; L606-L611 PolarHBondContact O-N 3.31Å
607	D	69.7	Low	61.7	Low	13 Å²	13	81.6 Å²	81.6	7%	0.07	39%	0.387	C	S	.	.	I	π-helix	trans	-62.3	-62.1	173.1	173.3	23.8	0	0	0	111.9	H409 Y410 F603 W605 K609 Y610 L611 N612	H409-D607 IonicContact CE1-OD1 2.58Å; H409-D607 IonicContact CE1-OD2 3.49Å; H409-D607 PolarHBondContact CE1-OD2 3.37Å; H409-D607 IonicContact ND1-OD2 3.51Å; H409-D607 IonicContact NE2-OD2 2.93Å; Y410-D607 WeakPolarHBondContact CE1-OD1 3.4Å; Y410-D607 PolarHBondContact OH-OD1 3.45Å; F603-D607 HydrophobicContact CE1-CB 4.3Å; F603-D607 WeakPolarHBondContact O-CB 3.43Å; F603-D607 PolarHBondContact O-N 2.6Å; W605-D607 VanDerWaalsContact C-N 3.32Å; D607-K609 PolarHBondContact O-N 2.88Å; D607-Y610 PolarHBondContact O-N 3.01Å; D607-Y610 VanDerWaalsContact O-N 3.16Å; D607-L611 HydrophobicContact CB-CB 4.43Å; D607-L611 HydrophobicContact CB-CD1 4.23Å; D607-L611 PolarHBondContact O-N 2.98Å; D607-N612 WeakPolarHBondContact O-CB 3.42Å; D607-N612 PolarHBondContact O-N 3.13Å; D607-N612 WeakPolarHBondContact OD1-CB 3.49Å; D607-N612 PolarHBondContact OD1-N 2.68Å; D607-N612 VanDerWaalsContact OD1-N 3.11Å
608	A	63.5	Low	61.9	Low	15 Å²	15	84 Å²	84	12%	0.124	40%	0.396	C	S	.	.	I	π-helix	trans	-60.4	-16.7	-176.5	0	0	0	0	0	114.8	R597 L600 M604	R597-A608 PolarHBondContact NH2-O 3.05Å; L600-A608 HydrophobicContact CD1-CB 3.56Å; M604-A608 WeakPolarHBondContact O-CB 3.46Å; M604-A608 PolarHBondContact O-N 2.99Å
609	K	63.2	Low	62.2	Low	102 Å²	102	77.9 Å²	77.9	44%	0.443	37%	0.369	S	S	.	.	I	π-helix	trans	-100.5	-33.9	177.3	-171.2	176.5	176	-164.2	0	114.3	W605 D607 P613	W605-K609 HydrophobicContact CD2-CD 4.47Å; W605-K609 HydrophobicContact CH2-CD 3.81Å; W605-K609 HydrophobicContact CZ2-CD 3.57Å; W605-K609 HydrophobicContact CZ3-CD 4.32Å; W605-K609 WeakPolarHBondContact O-CB 3.37Å; W605-K609 PolarHBondContact O-N 3.04Å; W605-K609 VanDerWaalsContact O-N 3.11Å; D607-K609 PolarHBondContact O-N 2.88Å; K609-P613 WeakPolarHBondContact O-CG 3.38Å
610	Y	64	Low	62.1	Low	130 Å²	130	75.7 Å²	75.7	51%	0.51	36%	0.36	S	S	.	.	I	π-helix	trans	-125.1	-54.1	-174	-61.5	-81.2	0	0	0	113.8	W605 L606 D607 F614	W605-Y610 HydrophobicContact CH2-CE2 4.45Å; W605-Y610 HydrophobicContact CZ3-CE2 4.26Å; L606-Y610 HydrophobicContact CG-CD2 4.49Å; L606-Y610 WeakPolarHBondContact O-CB 3.47Å; L606-Y610 PolarHBondContact O-N 3.24Å; D607-Y610 PolarHBondContact O-N 3.01Å; D607-Y610 VanDerWaalsContact O-N 3.16Å; Y610-F614 WeakPolarHBondContact O-CB 3.2Å; Y610-F614 PolarHBondContact O-N 2.95Å
611	L	69.6	Low	61.6	Low	48 Å²	48	82.2 Å²	82.2	25%	0.251	39%	0.389	S	S	.	.	I	π-helix	trans	-70.9	-53.4	-174.8	-53.7	172.6	0	0	0	111	Y410 F603 L606 D607 F614 F615	Y410-L611 HydrophobicContact CE1-CB 4.15Å; F603-L611 HydrophobicContact CE2-CD1 4.07Å; F603-L611 HydrophobicContact CZ-CD1 4.03Å; L606-L611 HydrophobicContact CD2-CD1 3.82Å; L606-L611 HydrophobicContact CD2-CD2 4.46Å; L606-L611 HydrophobicContact CD2-CG 3.91Å; L606-L611 PolarHBondContact O-N 3.31Å; D607-L611 HydrophobicContact CB-CB 4.43Å; D607-L611 HydrophobicContact CB-CD1 4.23Å; D607-L611 PolarHBondContact O-N 2.98Å; L611-F614 CarbonylContact O-C 3.54Å; L611-F614 WeakPolarHBondContact O-CA 3.38Å; L611-F614 WeakPolarHBondContact O-CB 3.41Å; L611-F614 PolarHBondContact O-N 2.92Å; L611-F615 HydrophobicContact CB-CD2 4.15Å; L611-F615 HydrophobicContact CB-CE2 4.39Å; L611-F615 HydrophobicContact CD2-CE2 4.11Å; L611-F615 VanDerWaalsContact O-CD2 3.27Å; L611-F615 WeakPolarHBondContact O-CD2 3.42Å; L611-F615 PolarHBondContact O-N 3.32Å
612	N	68.7	Low	61	Low	30 Å²	30	82.1 Å²	82.1	16%	0.16	39%	0.391	C	S	.	.	H	α-helix	trans	-50.9	-59.2	178.6	-169.1	-28.9	0	0	0	111.9	D607 F614 F615 T616	D607-N612 WeakPolarHBondContact O-CB 3.42Å; D607-N612 PolarHBondContact O-N 3.13Å; D607-N612 WeakPolarHBondContact OD1-CB 3.49Å; D607-N612 PolarHBondContact OD1-N 2.68Å; D607-N612 VanDerWaalsContact OD1-N 3.11Å; N612-F614 PolarHBondContact O-N 3.44Å; N612-F614 VanDerWaalsContact O-N 3.1Å; N612-F615 PolarHBondContact O-N 2.9Å; N612-T616 WeakPolarHBondContact O-CA 3.31Å; N612-T616 WeakPolarHBondContact O-CB 3.41Å; N612-T616 PolarHBondContact O-N 3.34Å; N612-T616 PolarHBondContact O-OG1 3.09Å; N612-T616 WeakPolarHBondContact OD1-CG2 3.25Å; N612-T616 PolarHBondContact OD1-OG1 2.79Å
613	P	59.9	Low	60.3	Low	44 Å²	44	81.4 Å²	81.4	29%	0.286	37%	0.373	S	S	.	.	H	α-helix	trans	-65.6	-15.3	178.4	26.9	-35.3	0	0	0	115.3	K363 K609	K363-P613 PolarHBondContact NZ-O 2.91Å; K609-P613 WeakPolarHBondContact O-CG 3.38Å
614	F	71.1	Confident	60	Low	120 Å²	120	78.6 Å²	78.6	53%	0.526	36%	0.364	S	S	.	.	H	α-helix	trans	-83.9	-40.7	173.3	-176.8	-95.8	0	0	0	112.4	L360 K363 Y610 L611 N612	L360-F614 HydrophobicContact CD1-CE1 4.42Å; L360-F614 HydrophobicContact CD2-CD1 4.26Å; L360-F614 HydrophobicContact CD2-CE1 3.82Å; L360-F614 HydrophobicContact CD2-CZ 4.43Å; K363-F614 VanDerWaalsContact NZ-C 3.33Å; K363-F614 PolarHBondContact NZ-O 3.29Å; Y610-F614 WeakPolarHBondContact O-CB 3.2Å; Y610-F614 PolarHBondContact O-N 2.95Å; L611-F614 CarbonylContact O-C 3.54Å; L611-F614 WeakPolarHBondContact O-CA 3.38Å; L611-F614 WeakPolarHBondContact O-CB 3.41Å; L611-F614 PolarHBondContact O-N 2.92Å; N612-F614 PolarHBondContact O-N 3.44Å; N612-F614 VanDerWaalsContact O-N 3.1Å
615	F	71	Confident	59.6	Low	22 Å²	22	81.9 Å²	81.9	10%	0.096	38%	0.382	C	S	.	.	H	α-helix	trans	-91.7	-34.9	-178.5	-70	-71.3	0	0	0	113.9	L356 A359 L360 K363 Y410 N414 L611 N612	L356-F615 HydrophobicContact CB-CD1 4.28Å; L356-F615 HydrophobicContact CB-CE1 3.77Å; L356-F615 HydrophobicContact CB-CZ 4.2Å; L356-F615 HydrophobicContact CD1-CE1 4.39Å; L356-F615 HydrophobicContact CD1-CE2 4.38Å; L356-F615 HydrophobicContact CD1-CZ 3.97Å; L356-F615 HydrophobicContact CD2-CD1 3.87Å; L356-F615 HydrophobicContact CD2-CD2 3.9Å; L356-F615 HydrophobicContact CD2-CE1 3.84Å; L356-F615 HydrophobicContact CD2-CE2 3.88Å; L356-F615 HydrophobicContact CD2-CG 3.92Å; L356-F615 HydrophobicContact CD2-CZ 3.86Å; L356-F615 HydrophobicContact CG-CE1 4.2Å; L356-F615 HydrophobicContact CG-CZ 4.22Å; A359-F615 HydrophobicContact CB-CB 4.34Å; A359-F615 HydrophobicContact CB-CD1 4.45Å; L360-F615 HydrophobicContact CD1-CD1 4.38Å; L360-F615 HydrophobicContact CD1-CE1 3.84Å; L360-F615 HydrophobicContact CD2-CD1 3.67Å; L360-F615 HydrophobicContact CD2-CE1 3.87Å; L360-F615 HydrophobicContact CG-CD1 3.7Å; L360-F615 HydrophobicContact CG-CE1 3.68Å; K363-F615 WeakPolarHBondContact CD-O 3.49Å; Y410-F615 HydrophobicContact CD1-CB 3.65Å; Y410-F615 HydrophobicContact CD1-CD2 4.41Å; Y410-F615 HydrophobicContact CD1-CG 4.35Å; Y410-F615 HydrophobicContact CE1-CB 4.35Å; Y410-F615 HydrophobicContact CE1-CD2 4.33Å; Y410-F615 HydrophobicContact CG-CB 4.02Å; N414-F615 PolarHBondContact ND2-O 3.2Å; L611-F615 HydrophobicContact CB-CD2 4.15Å; L611-F615 HydrophobicContact CB-CE2 4.39Å; L611-F615 HydrophobicContact CD2-CE2 4.11Å; L611-F615 VanDerWaalsContact O-CD2 3.27Å; L611-F615 WeakPolarHBondContact O-CD2 3.42Å; L611-F615 PolarHBondContact O-N 3.32Å; N612-F615 PolarHBondContact O-N 2.9Å
616	T	61.4	Low	59.4	Low	13 Å²	13	81 Å²	81	8%	0.08	38%	0.383	C	S	.	.	S	Bend	trans	-87	148.1	171.7	73.8	0	0	0	0	111.1	K363 Y410 H413 N414 N612	K363-T616 WeakPolarHBondContact CE-O 3.4Å; K363-T616 PolarHBondContact NZ-O 3.14Å; Y410-T616 HydrophobicContact CD1-CG2 4.49Å; H413-T616 HydrophobicContact CB-CG2 3.98Å; N414-T616 VanDerWaalsContact OD1-CA 3.25Å; N414-T616 WeakPolarHBondContact OD1-CA 3.24Å; N612-T616 WeakPolarHBondContact O-CA 3.31Å; N612-T616 WeakPolarHBondContact O-CB 3.41Å; N612-T616 PolarHBondContact O-N 3.34Å; N612-T616 PolarHBondContact O-OG1 3.09Å; N612-T616 WeakPolarHBondContact OD1-CG2 3.25Å; N612-T616 PolarHBondContact OD1-OG1 2.79Å
617	R	57	Low	59	Low	74 Å²	74	78.3 Å²	78.3	28%	0.279	38%	0.375	S	S	.	.			trans	-83.9	134.3	170.5	-170.8	167.6	173.9	176.9	-8.5	108.1	K363 D366 N414 L619	K363-R617 HydrophobicContact CG-CB 4.25Å; D366-R617 IonicContact OD1-NH1 3.52Å; D366-R617 PolarHBondContact OD1-NH1 2.9Å; D366-R617 IonicContact OD2-CZ 2.66Å; D366-R617 IonicContact OD2-NH1 3.71Å; D366-R617 PolarHBondContact OD2-NH1 3.19Å; D366-R617 IonicContact OD2-NH2 2.76Å; D366-R617 PolarHBondContact OD2-NH2 2.91Å; N414-R617 PolarHBondContact OD1-N 3.37Å; R617-L619 PolarHBondContact O-N 3.06Å; R617-L619 VanDerWaalsContact O-N 3.09Å
618	R	53.2	Low	58.6	Low	215 Å²	215	85 Å²	85	81%	0.811	40%	0.399	S	S	*	.			trans	-64	113.9	167.2	-69.3	-174.6	-177.6	-174.7	1	107.5	T620	R618-T620 PolarHBondContact O-N 3.22Å
619	L	50	Low	58.8	Low	57 Å²	57	88.6 Å²	88.6	30%	0.298	42%	0.415	S	S	.	.			trans	-66.7	119.6	165.2	-77.6	85.1	0	0	0	107.8	R617 L624	R617-L619 PolarHBondContact O-N 3.06Å; R617-L619 VanDerWaalsContact O-N 3.09Å; L619-L624 HydrophobicContact CB-CD1 4.42Å; L619-L624 HydrophobicContact CB-CG 4.28Å; L619-L624 HydrophobicContact CD2-CD2 3.65Å; L619-L624 HydrophobicContact CD2-CG 3.96Å
620	T	48.7	Very low	58.9	Low	71 Å²	71	88.8 Å²	88.8	44%	0.436	42%	0.417	S	S	.	.			trans	-62.2	144.8	164.8	-7.8	0	0	0	0	108.4	R618 E622 D623 L624	R618-T620 PolarHBondContact O-N 3.22Å; T620-E622 PolarHBondContact O-N 3.4Å; T620-E622 VanDerWaalsContact O-N 3.14Å; T620-D623 WeakPolarHBondContact CB-OD1 3.38Å; T620-D623 WeakPolarHBondContact O-CB 3.43Å; T620-D623 PolarHBondContact O-N 3.32Å; T620-D623 PolarHBondContact OG1-OD1 3.45Å; T620-L624 PolarHBondContact O-N 3.03Å
621	Q	43.2	Very low	58.8	Low	173 Å²	173	88 Å²	88	81%	0.808	42%	0.419	S	S	*	.	H	α-helix	trans	-58.5	-27	173.1	-85.6	-171.5	-34.8	0	0	111.8	L624 L625	Q621-L624 PolarHBondContact O-N 3.01Å; Q621-L625 WeakPolarHBondContact O-CB 3.39Å; Q621-L625 PolarHBondContact O-N 3.36Å
622	E	45.2	Very low	58.8	Low	151 Å²	151	92.4 Å²	92.4	71%	0.706	44%	0.437	S	S	*	.	H	α-helix	trans	-63.4	-45	172.8	-60.1	177.5	149.8	0	0	112.3	T620 L624 L625 H626	T620-E622 PolarHBondContact O-N 3.4Å; T620-E622 VanDerWaalsContact O-N 3.14Å; E622-L624 VanDerWaalsContact C-N 3.31Å; E622-L624 PolarHBondContact O-N 2.65Å; E622-L625 PolarHBondContact O-N 3.1Å; E622-H626 VanDerWaalsContact O-CB 3.24Å; E622-H626 WeakPolarHBondContact O-CB 3.29Å; E622-H626 PolarHBondContact O-N 3.3Å
623	D	53.6	Low	59.1	Low	46 Å²	46	95 Å²	95	25%	0.246	45%	0.454	C	S	.	.	H	α-helix	trans	-56.7	-45.3	174.4	-69.5	46	0	0	0	111.2	R368 T620 H626 G627	R368-D623 IonicContact CZ-OD2 2.7Å; R368-D623 VanDerWaalsContact CZ-OD2 3.23Å; R368-D623 IonicContact NH1-OD2 2.6Å; R368-D623 PolarHBondContact NH1-OD2 3.34Å; R368-D623 IonicContact NH2-OD2 3.12Å; R368-D623 PolarHBondContact NH2-OD2 3.23Å; T620-D623 WeakPolarHBondContact CB-OD1 3.38Å; T620-D623 WeakPolarHBondContact O-CB 3.43Å; T620-D623 PolarHBondContact O-N 3.32Å; T620-D623 PolarHBondContact OG1-OD1 3.45Å; D623-H626 PolarHBondContact O-N 3.17Å; D623-G627 PolarHBondContact O-N 3.37Å
624	L	54.9	Low	59.5	Low	68 Å²	68	98 Å²	98	36%	0.356	47%	0.467	S	S	.	.	H	α-helix	trans	-66	-44.6	179.1	-74.9	168.6	0	0	0	111.9	L619 T620 Q621 E622 H626 G627 R628	L619-L624 HydrophobicContact CB-CD1 4.42Å; L619-L624 HydrophobicContact CB-CG 4.28Å; L619-L624 HydrophobicContact CD2-CD2 3.65Å; L619-L624 HydrophobicContact CD2-CG 3.96Å; T620-L624 PolarHBondContact O-N 3.03Å; Q621-L624 PolarHBondContact O-N 3.01Å; E622-L624 VanDerWaalsContact C-N 3.31Å; E622-L624 PolarHBondContact O-N 2.65Å; L624-H626 VanDerWaalsContact C-N 3.32Å; L624-H626 PolarHBondContact O-N 3.01Å; L624-G627 PolarHBondContact O-N 3.47Å; L624-R628 VanDerWaalsContact O-CB 3.31Å; L624-R628 WeakPolarHBondContact O-CB 3.22Å; L624-R628 PolarHBondContact O-N 3.49Å
625	L	53.2	Low	59.7	Low	115 Å²	115	95.3 Å²	95.3	60%	0.602	46%	0.461	S	S	*	.	H	α-helix	trans	-62.7	-41.9	176.6	-164.5	110	0	0	0	110.8	Q621 E622 R628 I629	Q621-L625 WeakPolarHBondContact O-CB 3.39Å; Q621-L625 PolarHBondContact O-N 3.36Å; E622-L625 PolarHBondContact O-N 3.1Å; L625-R628 PolarHBondContact O-N 3.42Å; L625-I629 HydrophobicContact CD2-CD1 3.81Å; L625-I629 HydrophobicContact CG-CD1 4.24Å; L625-I629 WeakPolarHBondContact O-CB 3.38Å; L625-I629 VanDerWaalsContact O-CG1 3.24Å; L625-I629 WeakPolarHBondContact O-CG1 3.36Å; L625-I629 PolarHBondContact O-N 3.39Å
626	H	60.7	Low	59.9	Low	114 Å²	114	98.8 Å²	98.8	53%	0.528	48%	0.48	S	S	.	.	H	α-helix	trans	-69.2	-36.5	179.9	-155.1	-51.2	0	0	0	112.4	E622 D623 L624 Q630	E622-H626 VanDerWaalsContact O-CB 3.24Å; E622-H626 WeakPolarHBondContact O-CB 3.29Å; E622-H626 PolarHBondContact O-N 3.3Å; D623-H626 PolarHBondContact O-N 3.17Å; L624-H626 VanDerWaalsContact C-N 3.32Å; L624-H626 PolarHBondContact O-N 3.01Å; H626-Q630 WeakPolarHBondContact O-CB 3.44Å; H626-Q630 WeakPolarHBondContact O-CG 3.46Å; H626-Q630 PolarHBondContact O-N 2.75Å
627	G	57.7	Low	60.6	Low	24 Å²	24	103.3 Å²	103.3	25%	0.247	50%	0.499	C	S	.	.	H	α-helix	trans	-67	-44.1	171.3	0	0	0	0	0	112.5	D623 L624 I629 Q630 M631	D623-G627 PolarHBondContact O-N 3.37Å; L624-G627 PolarHBondContact O-N 3.47Å; G627-I629 VanDerWaalsContact C-N 3.31Å; G627-I629 PolarHBondContact O-N 2.8Å; G627-Q630 PolarHBondContact O-N 3.13Å; G627-M631 WeakPolarHBondContact O-CB 3.14Å; G627-M631 PolarHBondContact O-N 3.07Å
628	R	60.7	Low	61.3	Low	153 Å²	153	107 Å²	107	58%	0.577	51%	0.512	S	S	*	.	H	α-helix	trans	-62.7	-35.9	175.2	-175.1	177.7	-84.3	-178.5	-7.6	112.1	E587 L624 L625 K632	E587-R628 IonicContact OE1-NH2 3.42Å; E587-R628 PolarHBondContact OE1-NH2 2.88Å; L624-R628 VanDerWaalsContact O-CB 3.31Å; L624-R628 WeakPolarHBondContact O-CB 3.22Å; L624-R628 PolarHBondContact O-N 3.49Å; L625-R628 PolarHBondContact O-N 3.42Å; R628-K632 WeakPolarHBondContact O-CB 3.47Å; R628-K632 WeakPolarHBondContact O-CG 3.49Å; R628-K632 PolarHBondContact O-N 2.9Å; R628-K632 VanDerWaalsContact O-N 3.15Å
629	I	67.4	Low	62.3	Low	91 Å²	91	104.2 Å²	104.2	47%	0.467	50%	0.503	S	S	.	.	H	α-helix	trans	-65.5	-53.2	171.1	-72	164.2	0	0	0	110.3	L625 G627 M631 K632 T633	L625-I629 HydrophobicContact CD2-CD1 3.81Å; L625-I629 HydrophobicContact CG-CD1 4.24Å; L625-I629 WeakPolarHBondContact O-CB 3.38Å; L625-I629 VanDerWaalsContact O-CG1 3.24Å; L625-I629 WeakPolarHBondContact O-CG1 3.36Å; L625-I629 PolarHBondContact O-N 3.39Å; G627-I629 VanDerWaalsContact C-N 3.31Å; G627-I629 PolarHBondContact O-N 2.8Å; I629-M631 VanDerWaalsContact C-N 3.31Å; I629-M631 PolarHBondContact O-N 3.5Å; I629-K632 PolarHBondContact O-N 3.38Å; I629-T633 PolarHBondContact O-N 2.93Å; I629-T633 PolarHBondContact O-OG1 2.88Å; I629-T633 VanDerWaalsContact O-OG1 3.11Å
630	Q	66.8	Low	63.5	Low	105 Å²	105	107 Å²	107	49%	0.491	52%	0.515	S	S	.	.	H	α-helix	trans	-57.4	-42.3	-179.8	-79.5	177.5	-23.1	0	0	112.8	H626 G627 T633 L634	H626-Q630 WeakPolarHBondContact O-CB 3.44Å; H626-Q630 WeakPolarHBondContact O-CG 3.46Å; H626-Q630 PolarHBondContact O-N 2.75Å; G627-Q630 PolarHBondContact O-N 3.13Å; Q630-T633 PolarHBondContact O-N 3.46Å; Q630-L634 WeakPolarHBondContact O-CG 3.25Å; Q630-L634 PolarHBondContact O-N 3.26Å
631	M	61.6	Low	64.7	Low	113 Å²	113	108.3 Å²	108.3	56%	0.557	52%	0.516	S	S	*	.	H	α-helix	trans	-65.9	-43.5	178.1	-163.4	166	-175.1	0	0	111.3	G627 I629 T633 L634 T635	G627-M631 WeakPolarHBondContact O-CB 3.14Å; G627-M631 PolarHBondContact O-N 3.07Å; I629-M631 VanDerWaalsContact C-N 3.31Å; I629-M631 PolarHBondContact O-N 3.5Å; M631-T633 PolarHBondContact O-N 2.96Å; M631-L634 PolarHBondContact O-N 3.17Å; M631-T635 PolarHBondContact O-N 2.84Å; M631-T635 PolarHBondContact O-OG1 3.26Å; M631-T635 VanDerWaalsContact O-OG1 3.07Å
632	K	69.1	Low	66	Low	141 Å²	141	104.2 Å²	104.2	61%	0.613	50%	0.502	S	S	*	.	H	α-helix	trans	-61.8	-40.1	172	-78.5	-169.2	172.5	-166	0	113	R628 I629 T635 N636	R628-K632 WeakPolarHBondContact O-CB 3.47Å; R628-K632 WeakPolarHBondContact O-CG 3.49Å; R628-K632 PolarHBondContact O-N 2.9Å; R628-K632 VanDerWaalsContact O-N 3.15Å; I629-K632 PolarHBondContact O-N 3.38Å; K632-T635 PolarHBondContact O-N 3.22Å; K632-N636 WeakPolarHBondContact O-CB 3.28Å; K632-N636 VanDerWaalsContact O-CG 3.26Å; K632-N636 PolarHBondContact O-N 3.33Å; K632-N636 PolarHBondContact O-OD1 2.86Å
633	T	73.9	Confident	66.9	Low	85 Å²	85	107.9 Å²	107.9	52%	0.521	51%	0.51	S	S	.	.	H	α-helix	trans	-64.6	-40.4	176.1	-57.7	0	0	0	0	111.6	I629 Q630 M631 K637	I629-T633 PolarHBondContact O-N 2.93Å; I629-T633 PolarHBondContact O-OG1 2.88Å; I629-T633 VanDerWaalsContact O-OG1 3.11Å; Q630-T633 PolarHBondContact O-N 3.46Å; M631-T633 PolarHBondContact O-N 2.96Å; T633-K637 VanDerWaalsContact O-CB 3.24Å; T633-K637 WeakPolarHBondContact O-CB 3.47Å; T633-K637 PolarHBondContact O-N 3.27Å
634	L	70.2	Confident	67	Low	106 Å²	106	113 Å²	113	56%	0.555	53%	0.532	S	S	*	.	H	α-helix	trans	-65.3	-45	174.3	-77.3	164.4	0	0	0	111.9	Q630 M631 K637 W638	Q630-L634 WeakPolarHBondContact O-CG 3.25Å; Q630-L634 PolarHBondContact O-N 3.26Å; M631-L634 PolarHBondContact O-N 3.17Å; L634-K637 PolarHBondContact O-N 3.02Å; L634-W638 WeakPolarHBondContact O-CB 3.46Å; L634-W638 PolarHBondContact O-N 3.17Å
635	T	73.6	Confident	66.6	Low	65 Å²	65	111 Å²	111	40%	0.399	53%	0.529	S	S	.	.	H	α-helix	trans	-61.6	-46.4	175.5	-59.9	0	0	0	0	111.5	M631 K632 W638 Y639	M631-T635 PolarHBondContact O-N 2.84Å; M631-T635 PolarHBondContact O-OG1 3.26Å; M631-T635 VanDerWaalsContact O-OG1 3.07Å; K632-T635 PolarHBondContact O-N 3.22Å; T635-W638 PolarHBondContact O-N 3.31Å; T635-Y639 HydrophobicContact CG2-CD2 3.9Å; T635-Y639 HydrophobicContact CG2-CE2 4.05Å; T635-Y639 WeakPolarHBondContact O-CD2 3.41Å; T635-Y639 PolarHBondContact O-N 3.03Å
636	N	75.4	Confident	66.4	Low	94 Å²	94	112.8 Å²	112.8	50%	0.503	55%	0.547	S	S	.	.	H	α-helix	trans	-62.2	-46.9	177.7	-74.9	13.9	0	0	0	111.6	K632 W638 Y639 E640	K632-N636 WeakPolarHBondContact O-CB 3.28Å; K632-N636 VanDerWaalsContact O-CG 3.26Å; K632-N636 PolarHBondContact O-N 3.33Å; K632-N636 PolarHBondContact O-OD1 2.86Å; N636-W638 VanDerWaalsContact C-N 3.29Å; N636-W638 PolarHBondContact O-N 2.92Å; N636-Y639 CarbonylContact O-C 3.56Å; N636-Y639 WeakPolarHBondContact O-CA 3.47Å; N636-Y639 WeakPolarHBondContact O-CB 3.34Å; N636-Y639 PolarHBondContact O-N 3.16Å; N636-Y639 VanDerWaalsContact O-N 3.1Å; N636-E640 WeakPolarHBondContact O-CG 3.39Å; N636-E640 PolarHBondContact O-N 2.63Å
637	K	75.8	Confident	65.7	Low	108 Å²	108	112.7 Å²	112.7	47%	0.47	56%	0.559	S	S	.	*	H	α-helix	trans	-62.5	-36.2	178.1	-170.8	171.8	-171	-69.9	0	112.1	T633 L634 E640 E641	T633-K637 VanDerWaalsContact O-CB 3.24Å; T633-K637 WeakPolarHBondContact O-CB 3.47Å; T633-K637 PolarHBondContact O-N 3.27Å; L634-K637 PolarHBondContact O-N 3.02Å; K637-E640 PolarHBondContact O-N 3Å; K637-E641 IonicContact NZ-OE1 2.95Å; K637-E641 PolarHBondContact NZ-OE1 2.88Å; K637-E641 WeakPolarHBondContact O-CB 3.18Å; K637-E641 VanDerWaalsContact O-CG 3.3Å; K637-E641 WeakPolarHBondContact O-CG 3.42Å; K637-E641 PolarHBondContact O-N 2.88Å
638	W	73.2	Confident	65	Low	151 Å²	151	115 Å²	115	57%	0.572	58%	0.583	S	S	*	*	H	α-helix	trans	-68.9	-38.9	172.7	-174.6	81.3	0	0	0	112.2	L634 T635 N636 E640 E641 V642	L634-W638 WeakPolarHBondContact O-CB 3.46Å; L634-W638 PolarHBondContact O-N 3.17Å; T635-W638 PolarHBondContact O-N 3.31Å; N636-W638 VanDerWaalsContact C-N 3.29Å; N636-W638 PolarHBondContact O-N 2.92Å; W638-E640 VanDerWaalsContact C-N 3.33Å; W638-E640 PolarHBondContact O-N 3.3Å; W638-E641 PolarHBondContact O-N 3.06Å; W638-V642 HydrophobicContact CD2-CG2 3.88Å; W638-V642 HydrophobicContact CE3-CG2 4.2Å; W638-V642 HydrophobicContact CG-CG2 4.44Å; W638-V642 HydrophobicContact CH2-CG2 4.09Å; W638-V642 HydrophobicContact CZ2-CG2 3.73Å; W638-V642 HydrophobicContact CZ3-CG2 4.3Å; W638-V642 VanDerWaalsContact O-CB 3.29Å; W638-V642 WeakPolarHBondContact O-CB 3.28Å; W638-V642 VanDerWaalsContact O-CG2 3.24Å; W638-V642 WeakPolarHBondContact O-CG2 3.16Å; W638-V642 PolarHBondContact O-N 2.88Å
639	Y	73.8	Confident	64.2	Low	158 Å²	158	112.3 Å²	112.3	62%	0.62	59%	0.588	S	S	*	*	H	α-helix	trans	-62.9	-37.7	171.4	-99.8	-84.2	0	0	0	112.4	T635 N636 R643	T635-Y639 HydrophobicContact CG2-CD2 3.9Å; T635-Y639 HydrophobicContact CG2-CE2 4.05Å; T635-Y639 WeakPolarHBondContact O-CD2 3.41Å; T635-Y639 PolarHBondContact O-N 3.03Å; N636-Y639 CarbonylContact O-C 3.56Å; N636-Y639 WeakPolarHBondContact O-CA 3.47Å; N636-Y639 WeakPolarHBondContact O-CB 3.34Å; N636-Y639 PolarHBondContact O-N 3.16Å; N636-Y639 VanDerWaalsContact O-N 3.1Å; Y639-R643 WeakPolarHBondContact O-CB 3.41Å; Y639-R643 PolarHBondContact O-N 3.12Å
640	E	74.9	Confident	63.3	Low	114 Å²	114	116.8 Å²	116.8	53%	0.533	61%	0.607	S	S	.	*	H	α-helix	trans	-66.3	-48.4	173.9	-72.5	163.3	-178.9	0	0	111	N636 K637 W638 V642 R643 Q644	N636-E640 WeakPolarHBondContact O-CG 3.39Å; N636-E640 PolarHBondContact O-N 2.63Å; K637-E640 PolarHBondContact O-N 3Å; W638-E640 VanDerWaalsContact C-N 3.33Å; W638-E640 PolarHBondContact O-N 3.3Å; E640-V642 PolarHBondContact O-N 3.46Å; E640-R643 CarbonylContact O-C 3.57Å; E640-R643 PolarHBondContact O-N 2.97Å; E640-Q644 WeakPolarHBondContact O-CB 3.5Å; E640-Q644 WeakPolarHBondContact O-CG 3.48Å; E640-Q644 PolarHBondContact O-N 3.48Å
641	E	73.2	Confident	62.1	Low	100 Å²	100	119.3 Å²	119.3	47%	0.467	62%	0.623	S	S	.	*	H	α-helix	trans	-63.9	-35.5	176.8	-74.7	170.9	-177.7	0	0	113.3	K637 W638 Q644	K637-E641 IonicContact NZ-OE1 2.95Å; K637-E641 PolarHBondContact NZ-OE1 2.88Å; K637-E641 WeakPolarHBondContact O-CB 3.18Å; K637-E641 VanDerWaalsContact O-CG 3.3Å; K637-E641 WeakPolarHBondContact O-CG 3.42Å; K637-E641 PolarHBondContact O-N 2.88Å; W638-E641 PolarHBondContact O-N 3.06Å; E641-Q644 CarbonylContact O-C 3.54Å
642	V	70.5	Confident	61.2	Low	86 Å²	86	122.1 Å²	122.1	52%	0.521	64%	0.641	S	S	.	*	H	α-helix	trans	-75.2	-28.7	175.1	169.3	0	0	0	0	111.9	W638 E640	W638-V642 HydrophobicContact CD2-CG2 3.88Å; W638-V642 HydrophobicContact CE3-CG2 4.2Å; W638-V642 HydrophobicContact CG-CG2 4.44Å; W638-V642 HydrophobicContact CH2-CG2 4.09Å; W638-V642 HydrophobicContact CZ2-CG2 3.73Å; W638-V642 HydrophobicContact CZ3-CG2 4.3Å; W638-V642 VanDerWaalsContact O-CB 3.29Å; W638-V642 WeakPolarHBondContact O-CB 3.28Å; W638-V642 VanDerWaalsContact O-CG2 3.24Å; W638-V642 WeakPolarHBondContact O-CG2 3.16Å; W638-V642 PolarHBondContact O-N 2.88Å; E640-V642 PolarHBondContact O-N 3.46Å
643	R	65.4	Low	59.9	Low	229 Å²	229	123.9 Å²	123.9	86%	0.864	65%	0.651	S	S	*	*	H	α-helix	trans	-77.1	-33.3	172.9	-172.2	171.9	-179.4	169	-2.2	111.7	Y639 E640 G645	Y639-R643 WeakPolarHBondContact O-CB 3.41Å; Y639-R643 PolarHBondContact O-N 3.12Å; E640-R643 CarbonylContact O-C 3.57Å; E640-R643 PolarHBondContact O-N 2.97Å; R643-G645 PolarHBondContact O-N 3.39Å; R643-G645 VanDerWaalsContact O-N 3.13Å
644	Q	54.6	Low	58.2	Low	152 Å²	152	127.2 Å²	127.2	71%	0.71	67%	0.666	S	S	*	*	S	Bend	trans	-84	56.5	170.8	-67.6	-179.3	-12.4	0	0	111.2	E640 E641	E640-Q644 WeakPolarHBondContact O-CB 3.5Å; E640-Q644 WeakPolarHBondContact O-CG 3.48Å; E640-Q644 PolarHBondContact O-N 3.48Å; E641-Q644 CarbonylContact O-C 3.54Å
645	G	47	Very low	56.8	Low	28 Å²	28	131.9 Å²	131.9	29%	0.289	69%	0.685	S	S	.	*			trans	-61.4	169.7	173.9	0	0	0	0	0	112.8	R643 S647 G648	R643-G645 PolarHBondContact O-N 3.39Å; R643-G645 VanDerWaalsContact O-N 3.13Å; G645-S647 PolarHBondContact O-N 3.31Å; G645-G648 PolarHBondContact O-N 3.44Å
646	P	48.4	Very low	55.2	Low	151 Å²	151	132.9 Å²	132.9	98%	0.981	70%	0.7	S	S	*	*	S	Bend	trans	-66.3	16.1	-171.6	-22.7	35.5	0	0	0	117.5
647	S	47.1	Very low	53.4	Low	113 Å²	113	137.1 Å²	137.1	79%	0.79	72%	0.717	S	S	*	*			trans	-129.9	58.7	173.2	60.2	0	0	0	0	108.6	G645	G645-S647 PolarHBondContact O-N 3.31Å
648	G	41.7	Very low	51.8	Low	73 Å²	73	140.2 Å²	140.2	75%	0.753	74%	0.737	S	S	*	*			trans	-115.7	54.8	-179.7	0	0	0	0	0	111.4	G645	G645-G648 PolarHBondContact O-N 3.44Å
649	S	45.3	Very low	49.9	Very low	96 Å²	96	144.6 Å²	144.6	67%	0.671	77%	0.771	S	S	*	*	S	Bend	trans	-154.1	136.3	173.5	58.5	0	0	0	0	107.4
650	E	47.3	Very low	48.8	Very low	184 Å²	184	143.9 Å²	143.9	86%	0.86	78%	0.778	S	S	*	*	S	Bend	trans	82.6	145	-157.9	-55.1	168.5	-172.9	0	0	111.5
651	D	42.4	Very low	47.4	Very low	158 Å²	158	145.5 Å²	145.5	85%	0.845	79%	0.791	S	S	*	*			trans	83	21.1	-177.9	-55.3	-5.3	0	0	0	119.9
652	D	41.8	Very low	45.9	Very low	173 Å²	173	148 Å²	148	93%	0.925	81%	0.809	S	S	*	*	S	Bend	trans	-92.6	3.7	169.8	-97	-20.7	0	0	0	114.4
653	E	41.6	Very low	44.5	Very low	177 Å²	177	151.6 Å²	151.6	83%	0.827	83%	0.826	S	S	*	*	S	Bend	trans	-100.4	-17.5	-174.5	-67.3	-163.9	139.8	0	0	115.7
654	D	40	Very low	43.2	Very low	156 Å²	156	146.8 Å²	146.8	83%	0.834	82%	0.824	S	S	*	*	G	3₁₀ helix	trans	-88.2	-13.2	-170.4	-89.2	0.6	0	0	0	115.4	A656	D654-A656 PolarHBondContact O-N 3.35Å
655	E	40.3	Very low	42.4	Very low	203 Å²	203	146.5 Å²	146.5	95%	0.949	83%	0.831	S	S	*	*	G	3₁₀ helix	trans	-85.8	24.2	180	-150.7	173.3	-142.8	0	0	113.5
656	A	38.8	Very low	42.1	Very low	87 Å²	87	154.9 Å²	154.9	72%	0.719	87%	0.87	S	S	*	*	G	3₁₀ helix	trans	-110.4	-7.9	-175.8	0	0	0	0	0	115.7	D654	D654-A656 PolarHBondContact O-N 3.35Å
657	E	37.9	Very low	41.6	Very low	182 Å²	182	155.2 Å²	155.2	85%	0.85	86%	0.862	S	S	*	*	S	Bend	trans	-112.6	21.6	-172.8	-145.3	177.9	-141.6	0	0	114.8
658	L	42.5	Very low	41.2	Very low	173 Å²	173	158.8 Å²	158.8	91%	0.906	87%	0.868	S	S	*	*			trans	-132.4	38.9	176.8	-76.9	178.4	0	0	0	114.9
659	L	34.4	Very low	41.1	Very low	243 Å²	243	166.5 Å²	166.5	100%	1.272	88%	0.878	S	S	*	*			trans	-136.2	0	164.7	-75.5	179	0	0	0	111.8

Retrieved 659 of 659 residues in 344.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).